GeneModel BLAST Result against human

BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001096-TA|BGIBMGA001096-PA|IPR006210|EGF,
IPR006209|EGF-like, IPR013111|EGF, extracellular, IPR001258|NHL
repeat, IPR006530|YD repeat, IPR011044|Quinoprotein amine
dehydrogenase, beta chain-like, IPR009072|Histone-fold,
IPR013032|EGF-like region, IPR001209|Ribosomal protein S14,
IPR000742|EGF-like, type 3
         (2969 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AB040888-1|BAA95979.2| 2450|Homo sapiens KIAA1455 protein protein.   1257   0.0  
Z85995-1|CAI42721.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog...  1199   0.0  
Z83823-1|CAI42742.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog...  1199   0.0  
Z81008-1|CAI42710.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog...  1199   0.0  
AL031075-1|CAI43065.1| 2725|Homo sapiens odz, odd Oz/ten-m homol...  1199   0.0  
AL023878-1|CAI42975.1| 2725|Homo sapiens odz, odd Oz/ten-m homol...  1199   0.0  
AL022718-3|CAI42154.1| 2725|Homo sapiens odz, odd Oz/ten-m homol...  1199   0.0  
AF100772-1|AAF04723.1| 2725|Homo sapiens tenascin-M1 protein.        1195   0.0  
AB032953-1|BAA86441.2| 2144|Homo sapiens KIAA1127 protein protein.   1115   0.0  
AB037723-1|BAA92540.3| 2016|Homo sapiens KIAA1302 protein protein.    924   0.0  
BX640737-1|CAE45850.1| 1399|Homo sapiens hypothetical protein pr...   433   e-120
X71923-1|CAA50739.1|  750|Homo sapiens tenascin-X precursor prot...   245   2e-63
U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein.            245   2e-63
AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein.         245   2e-63
AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein.         245   2e-63
AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein.        245   2e-63
AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein.         245   2e-63
AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein.         245   2e-63
AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB...   245   2e-63
X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein.              230   7e-59
AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachio...   230   7e-59
AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein pro...   230   7e-59
X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein.      229   9e-59
M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein.          229   9e-59
AK001336-1|BAA91633.1| 1045|Homo sapiens protein ( Homo sapiens ...   195   2e-48
AK001748-1|BAA91879.1|  964|Homo sapiens protein ( Homo sapiens ...   191   4e-47
BX537983-1|CAD97943.1| 1071|Homo sapiens hypothetical protein pr...   188   2e-46
M24630-1|AAA52703.1| 1625|Homo sapiens hexabrachion protein.          180   5e-44
AK056531-1|BAB71206.1|  730|Homo sapiens protein ( Homo sapiens ...   177   4e-43
AK027473-1|BAB55138.1|  625|Homo sapiens protein ( Homo sapiens ...   171   2e-41
AK027618-1|BAB55237.1|  849|Homo sapiens protein ( Homo sapiens ...   157   8e-37
Z94057-1|CAI21650.1| 1358|Homo sapiens tenascin R (restrictin, j...   137   5e-31
Z94055-1|CAI19943.1| 1358|Homo sapiens tenascin R (restrictin, j...   137   5e-31
Z67996-1|CAA91947.1| 1358|Homo sapiens tenascin-R (restrictin) p...   137   5e-31
X98085-1|CAA66709.1| 1358|Homo sapiens tenascin-R protein.            137   5e-31
BC129830-1|AAI29831.1| 1257|Homo sapiens TNR protein protein.         137   5e-31
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop...   134   6e-30
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop...   134   6e-30
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop...   134   6e-30
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.      134   6e-30
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.             134   6e-30
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.        130   6e-29
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.      129   1e-28
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.            122   2e-26
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag...   121   3e-26
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.              121   3e-26
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag...   121   3e-26
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd...   121   3e-26
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd...   121   3e-26
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd...   121   3e-26
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd...   121   3e-26
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.             121   3e-26
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.             121   3e-26
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J...   121   3e-26
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.            121   3e-26
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.       121   5e-26
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.                120   6e-26
AY358892-1|AAQ89251.1|  723|Homo sapiens DLL1 protein.                120   6e-26
AL078605-2|CAB89569.1|  723|Homo sapiens delta-like 1 (Drosophil...   120   6e-26
AF222310-1|AAG09716.1|  723|Homo sapiens Delta1 protein.              120   6e-26
AF196571-1|AAF05834.1|  723|Homo sapiens Delta-like-1 protein pr...   120   6e-26
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.              120   6e-26
AF003522-1|AAB61286.1|  723|Homo sapiens Delta protein.               120   6e-26
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.             120   6e-26
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.             120   8e-26
BC020198-1|AAH20198.1|  567|Homo sapiens MEGF10 protein protein.      119   1e-25
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178...   119   1e-25
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.                118   3e-25
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.                118   3e-25
D86566-1|BAA13116.1|  955|Homo sapiens notch related protein pro...   118   3e-25
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop...   118   3e-25
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop...   118   3e-25
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop...   118   3e-25
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso...   118   3e-25
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso...   118   3e-25
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop...   118   3e-25
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl...   118   4e-25
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl...   118   4e-25
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va...   118   4e-25
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant...   116   1e-24
AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar t...   114   5e-24
AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar t...   114   5e-24
BC063815-1|AAH63815.1|  647|Homo sapiens NOTCH4 protein protein.      113   1e-23
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.                  111   4e-23
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.             111   4e-23
AB023961-1|BAB20317.1|  502|Homo sapiens notch4 protein.              110   6e-23
BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein.      110   9e-23
BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein.      110   9e-23
BC018037-1|AAH18037.1|  379|Homo sapiens WNT inhibitory factor 1...   110   9e-23
AY358344-1|AAQ88710.1|  379|Homo sapiens WIF-1 protein.               110   9e-23
AL834326-1|CAD38994.1|  626|Homo sapiens hypothetical protein pr...   110   9e-23
AF122922-1|AAD25402.1|  379|Homo sapiens Wnt inhibitory factor-1...   110   9e-23
AB058677-1|BAB47410.1|  969|Homo sapiens MEGF11 protein (KIAA178...   110   9e-23
Z99715-2|CAI19286.1| 1299|Homo sapiens tenascin N protein.            108   3e-22
Z99297-1|CAI19966.1| 1299|Homo sapiens tenascin N protein.            108   3e-22
AL049689-1|CAB41260.1| 1294|Homo sapiens hypothetical protein pr...   108   3e-22
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr...   107   5e-22
BC106950-1|AAI06951.1|  685|Homo sapiens delta-like 4 (Drosophil...   105   3e-21
BC035009-1|AAH35009.1|  737|Homo sapiens delta/notch-like EGF re...   105   3e-21
BC024766-1|AAH24766.2|  454|Homo sapiens DNER protein protein.        105   3e-21
AY358894-1|AAQ89253.1|  685|Homo sapiens DLL4 protein.                105   3e-21
AY358891-1|AAQ89250.1|  737|Homo sapiens QPRR262 protein.             105   3e-21
AF442487-1|AAM21557.1|  737|Homo sapiens delta-notch-like EGF re...   105   3e-21
AF279305-1|AAF81912.1|  653|Homo sapiens delta 4 protein.             105   3e-21
AF253468-1|AAF76427.1|  685|Homo sapiens notch ligand DLL4 protein.   105   3e-21
AB043894-1|BAB18581.1|  685|Homo sapiens Delta-4 protein.             105   3e-21
AB036931-1|BAB16085.1|  685|Homo sapiens notch ligand delta-2 pr...   105   3e-21
BC036788-1|AAH36788.2|  494|Homo sapiens integrin, beta-like 1 (...   103   7e-21
AL355807-1|CAI14550.1|  494|Homo sapiens integrin, beta-like 1 (...   103   7e-21
AL160153-1|CAH73400.1|  494|Homo sapiens integrin, beta-like 1 (...   103   7e-21
AL139800-1|CAH71455.1|  494|Homo sapiens integrin, beta-like 1 (...   103   7e-21
AF072752-1|AAD17666.1|  494|Homo sapiens ten integrin EGF-like r...   103   7e-21
AE014302-1|AAN16024.1|  494|Homo sapiens ITGBL1 protein.              103   7e-21
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.    103   1e-20
D86864-1|BAA24070.1|  830|Homo sapiens acetyl LDL receptor protein.   103   1e-20
D63483-1|BAA09770.1|  830|Homo sapiens KIAA0149 protein.              103   1e-20
BC039735-1|AAH39735.1|  830|Homo sapiens scavenger receptor clas...   103   1e-20
AB052948-1|BAC02694.1|  569|Homo sapiens SREC-3 protein.              103   1e-20
AB052946-1|BAC02692.1|  830|Homo sapiens SREC protein.                103   1e-20
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai...   100   9e-20
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai...   100   9e-20
AB052949-1|BAC02695.1|  337|Homo sapiens SREC-4 protein.              100   9e-20
AB052947-1|BAC02693.1|  342|Homo sapiens SREC-2 protein.              100   9e-20
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.               100   9e-20
AB008375-1|BAA22994.1|  403|Homo sapiens osteoblast specific cys...    99   1e-19
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph...    97   1e-18
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph...    97   1e-18
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph...    97   1e-18
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph...    97   1e-18
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.                97   1e-18
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs...    96   1e-18
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso...    96   1e-18
AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso...    96   1e-18
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso...    96   1e-18
AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso...    96   1e-18
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.                 96   1e-18
AB208923-1|BAD92160.1|  441|Homo sapiens crumbs homolog 1 isofor...    96   1e-18
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.       96   2e-18
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p...    93   1e-17
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso...    93   1e-17
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso...    93   1e-17
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso...    93   1e-17
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso...    93   1e-17
AB052950-1|BAC02696.1|  744|Homo sapiens SREC-5 protein.               93   1e-17
AK123000-1|BAC85516.1| 1176|Homo sapiens  3 (HIVEP3).  protein.        92   2e-17
AK075065-1|BAC11381.1|  269|Homo sapiens protein ( Homo sapiens ...    91   6e-17
AB052951-1|BAC53753.1|  866|Homo sapiens SRECRP-1 protein.             91   7e-17
BC110320-1|AAI10321.1|  383|Homo sapiens EGF-like-domain, multip...    90   1e-16
BC084572-1|AAH84572.1|  343|Homo sapiens NOTCH2NL protein protein.     90   1e-16
AY358126-1|AAQ88493.1|  383|Homo sapiens PSGC2903 protein.             90   1e-16
AL359813-9|CAI23224.1|  383|Homo sapiens EGF-like-domain, multip...    90   1e-16
AF522196-1|AAN45861.1|  870|Homo sapiens scavenger receptor type...    90   1e-16
AB024433-1|BAD93345.1|  866|Homo sapiens NSR1 protein.                 90   1e-16
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ...    90   1e-16
BX537434-1|CAD97676.1|  236|Homo sapiens hypothetical protein pr...    89   2e-16
BC090943-1|AAH90943.1|  249|Homo sapiens NOTCH2NL protein protein.     89   2e-16
BC010154-1|AAH10154.3|  236|Homo sapiens Notch homolog 2 (Drosop...    89   2e-16
AL592307-2|CAH73994.1|  230|Homo sapiens Notch homolog 2 (Drosop...    89   2e-16
AL592307-1|CAH73993.1|  236|Homo sapiens Notch homolog 2 (Drosop...    89   2e-16
BC065219-1|AAH65219.2|  236|Homo sapiens Notch homolog 2 (Drosop...    89   3e-16
BC019835-1|AAH19835.1|  236|Homo sapiens Notch homolog 2 N-termi...    89   3e-16
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein.     88   4e-16
U77493-1|AAB19224.1|  263|Homo sapiens Notch2 protein.                 88   5e-16
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein.                 88   5e-16
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for...    88   5e-16
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein.     88   5e-16
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein.           88   5e-16
AF160476-1|AAF82398.1|  897|Homo sapiens CD44-like precursor FEL...    88   5e-16
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein.               88   5e-16
AC008273-1|AAF19247.2|  291|Homo sapiens unknown protein.              87   7e-16
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p...    87   1e-15
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f...    87   1e-15
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f...    87   1e-15
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f...    87   1e-15
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ...    87   1e-15
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.       87   1e-15
AK098809-1|BAC05419.1|  320|Homo sapiens protein ( Homo sapiens ...    83   1e-14
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein...    83   1e-14
Z12172-1|CAA78163.1|  383|Homo sapiens putative homeotic protein...    82   3e-14
D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein.       81   5e-14
DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein.                 81   5e-14
AL080120-1|CAB45719.1|  184|Homo sapiens hypothetical protein pr...    81   5e-14
AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein.           81   5e-14
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein...    81   5e-14
AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein.               81   5e-14
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro...    81   8e-14
AL359813-8|CAI23223.1|  377|Homo sapiens EGF-like-domain, multip...    81   8e-14
DQ126100-1|AAZ38943.1|  212|Homo sapiens brevideltin protein.          80   1e-13
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p...    79   2e-13
DQ138965-1|AAZ66768.1|  203|Homo sapiens truncated brevideltinin...    79   2e-13
DQ017081-1|AAY40461.1|  315|Homo sapiens secredeltin protein.          79   2e-13
BC014015-1|AAH14015.1|  383|Homo sapiens delta-like 1 homolog (D...    79   2e-13
BC013197-1|AAH13197.1|  383|Homo sapiens delta-like 1 homolog (D...    79   2e-13
BC007741-1|AAH07741.1|  383|Homo sapiens delta-like 1 homolog (D...    79   2e-13
AF187072-1|AAF08273.1|  515|Homo sapiens N-acetylglucosamine-1-p...    79   2e-13
X53587-1|CAA37656.1| 1822|Homo sapiens integrin beta 4 protein p...    79   3e-13
X52186-1|CAA36433.1| 1805|Homo sapiens integrin beta 4 subunit p...    79   3e-13
X51841-1|CAA36134.1| 1752|Homo sapiens protein ( Human mRNA for ...    79   3e-13
U66541-3|AAC51632.1| 1752|Homo sapiens beta4-integrin protein.         79   3e-13
U66541-2|AAC51634.1| 1805|Homo sapiens beta4-integrin protein.         79   3e-13
U66541-1|AAC51633.1| 1822|Homo sapiens beta4-integrin protein.         79   3e-13
U15981-1|AAA75365.1|  310|Homo sapiens dlk protein.                    79   3e-13
U15979-1|AAA75364.1|  382|Homo sapiens dlk protein.                    79   3e-13
BC126411-1|AAI26412.1| 1752|Homo sapiens integrin, beta 4 protein.     79   3e-13
BC118916-1|AAI18917.1| 1752|Homo sapiens ITGB4 protein protein.        79   3e-13
BC109238-1|AAI09239.1|  644|Homo sapiens ITGB4 protein protein.        79   3e-13
AF011375-1|AAB65421.1|  964|Homo sapiens integrin variant beta4E...    79   3e-13
AB208913-1|BAD92150.1| 1515|Homo sapiens integrin beta 4 isoform...    79   3e-13
AJ251004-1|CAB61345.1| 1873|Homo sapiens integrin beta 4 protein.      78   4e-13
S80335-1|AAB21332.1|  798|Homo sapiens integrin beta 7 subunit p...    77   1e-12
S49378-1|AAB23688.1|  798|Homo sapiens integrin beta 7 subunit p...    77   1e-12
M68892-1|AAA59184.1|  798|Homo sapiens integrin beta-7 subunit p...    77   1e-12
M62880-1|AAA59185.1|  798|Homo sapiens integrin beta-7 subunit p...    77   1e-12
L23823-1|AAA36118.1|  798|Homo sapiens integrin beta 7 subunit p...    77   1e-12
BC015916-1|AAH15916.1|  798|Homo sapiens ITGB7 protein protein.        77   1e-12
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec...    77   1e-12
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.            77   1e-12
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein...    77   1e-12
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re...    77   1e-12
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein...    77   1e-12
BX538049-1|CAD97988.1| 1323|Homo sapiens hypothetical protein pr...    76   2e-12
BC000218-1|AAH00218.1|  618|Homo sapiens delta-like 3 (Drosophil...    75   3e-12
AF241373-1|AAF62542.1|  618|Homo sapiens DLL3 protein precursor ...    75   3e-12
BX537918-1|CAD97901.1| 1441|Homo sapiens hypothetical protein pr...    75   5e-12
AY916667-1|AAX12481.1| 1497|Homo sapiens CCP module-containing p...    75   5e-12
AL158158-6|CAI14071.1| 1497|Homo sapiens sushi, von Willebrand f...    75   5e-12
AK075302-1|BAC11535.1|  587|Homo sapiens protein ( Homo sapiens ...    75   5e-12
AK075235-1|BAC11489.1| 1497|Homo sapiens protein ( Homo sapiens ...    75   5e-12
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro...    75   5e-12
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro...    75   5e-12
AB052957-1|BAC15607.1|  803|Homo sapiens soluble form FELE-1 pro...    75   5e-12
AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso...    74   7e-12
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso...    74   7e-12
AL137007-1|CAC10575.2|  199|Homo sapiens novel EGF-like domain c...    74   7e-12
AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso...    74   7e-12
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt...    74   7e-12
AK074121-1|BAB84947.1|  491|Homo sapiens FLJ00193 protein protein.     73   2e-11
AF009227-1|AAC51756.1|  768|Homo sapiens gamma-heregulin protein.      73   2e-11
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.                72   3e-11
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein.     72   3e-11
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.       72   3e-11
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.                72   3e-11
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.              71   6e-11
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.              71   6e-11
AF075240-1|AAD19336.1|  850|Homo sapiens SLIT1 protein protein.        71   6e-11
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.          71   6e-11
AL359813-7|CAI23222.1|  134|Homo sapiens EGF-like-domain, multip...    71   8e-11
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.                  69   2e-10
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro...    69   2e-10
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac...    69   2e-10
AC019127-1|AAY24260.1|  697|Homo sapiens unknown protein.              69   2e-10
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro...    69   2e-10
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.          69   3e-10
AB177801-1|BAD16737.1|  195|Homo sapiens fibrillin 1 protein.          69   3e-10
U95204-1|AAB71380.1|  784|Homo sapiens platelet membrane glycopr...    69   3e-10
M57494-1|AAA52600.1|  761|Homo sapiens platelet glycoprotein III...    69   3e-10
M35999-1|AAA35927.1|  788|Homo sapiens protein ( Human platelet ...    69   3e-10
M32686-1|AAA67537.1|  762|Homo sapiens glycoprotein IIIa protein.      69   3e-10
M20311-1|AAA60122.1|  788|Homo sapiens glycoprotein IIIa protein.      69   3e-10
J02703-1|AAA52589.1|  788|Homo sapiens ITGB3 protein.                  69   3e-10
BC127667-1|AAI27668.1|  788|Homo sapiens integrin, beta 3 (plate...    69   3e-10
BC127666-1|AAI27667.1|  788|Homo sapiens integrin, beta 3 (plate...    69   3e-10
M73780-1|AAA36034.1|  769|Homo sapiens integrin beta-8 subunit p...    68   5e-10
AC004130-1|AAQ96845.1|  769|Homo sapiens unknown protein.              68   5e-10
M35198-1|AAA36122.2|  788|Homo sapiens integrin beta-subunit pro...    67   8e-10
BC121178-1|AAI21179.1|  788|Homo sapiens integrin, beta 6 protein.     67   8e-10
AC080166-2|AAY24053.1|  449|Homo sapiens unknown protein.              67   8e-10
X53002-1|CAA37188.1|  799|Homo sapiens protein ( Human mRNA for ...    66   1e-09
M35011-1|AAA52707.1|  796|Homo sapiens ITGB5 protein.                  66   1e-09
J05633-1|AAA59183.1|  799|Homo sapiens ITGB5 protein.                  66   1e-09
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph...    66   1e-09
BC006541-1|AAH06541.1|  799|Homo sapiens integrin, beta 5 protein.     66   1e-09
AF193046-1|AAG22474.1|  277|Homo sapiens unknown protein.              66   1e-09
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.                66   1e-09
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula...    66   1e-09
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital...    66   1e-09
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.       66   1e-09
AB126077-1|BAD20204.1|  187|Homo sapiens keratin associated prot...    66   2e-09
AB011541-1|BAA32469.2| 2785|Homo sapiens MEGF8 protein.                66   2e-09
U77914-1|AAC50909.1|  263|Homo sapiens soluble protein Jagged pr...    66   2e-09
AL137311-1|CAB70690.1|  252|Homo sapiens hypothetical protein pr...    66   2e-09
AJ006692-1|CAA07188.1|  194|Homo sapiens ultra high sulfer kerat...    66   2e-09
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.          66   2e-09
AB126070-1|BAD20197.1|  278|Homo sapiens keratin associated prot...    66   2e-09
DQ309460-1|ABC26875.1|  231|Homo sapiens delta-like 1 protein.         65   4e-09
AY360461-1|AAQ62965.1|  187|Homo sapiens UHS KERB-like protein p...    65   4e-09
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ...    64   7e-09
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ...    64   7e-09
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ...    64   7e-09
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.          64   7e-09
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.          64   7e-09
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.          64   7e-09
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.           64   7e-09
U57523-1|AAB06946.1|  446|Homo sapiens protein ( Human nel homol...    63   1e-08
D83017-1|BAA11680.1|  810|Homo sapiens nel-related protein protein.    62   2e-08
BC096102-1|AAH96102.1|  810|Homo sapiens NEL-like 1 (chicken) pr...    62   2e-08
BC096101-1|AAH96101.1|  810|Homo sapiens NEL-like 1 (chicken) pr...    62   2e-08
BC069674-1|AAH69674.1|  810|Homo sapiens nel-like 1, precursor p...    62   2e-08
AF283412-1|AAL38110.1|  172|Homo sapiens candidate tumor suppres...    62   3e-08
AC092156-1|AAY15024.1|  330|Homo sapiens unknown protein.              62   3e-08
X07979-1|CAA30790.1|  798|Homo sapiens protein ( Human mRNA for ...    62   4e-08
BX537407-1|CAD97649.1|  823|Homo sapiens hypothetical protein pr...    62   4e-08
BC020057-1|AAH20057.1|  798|Homo sapiens integrin, beta 1 (fibro...    62   4e-08
AL365203-2|CAI14426.1|  798|Homo sapiens integrin, beta 1 (fibro...    62   4e-08
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact...    60   9e-08
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact...    60   9e-08
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact...    60   9e-08
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami...    60   9e-08
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re...    60   9e-08
Y00057-1|CAA68266.1|  761|Homo sapiens protein ( Human mRNA for ...    60   2e-07
X64072-1|CAA45427.1|  769|Homo sapiens integrin beta-2 subunit p...    60   2e-07
M15395-1|AAA59490.1|  769|Homo sapiens LYAM1 protein.                  60   2e-07
BC021077-1|AAH21077.1|  758|Homo sapiens ITGB2 protein protein.        60   2e-07
BC005861-1|AAH05861.1|  769|Homo sapiens ITGB2 protein protein.        60   2e-07
AL163300-3|CAB90553.1|  769|Homo sapiens cell surface adhesion g...    60   2e-07
AK222505-1|BAD96225.1|  769|Homo sapiens integrin beta chain, be...    60   2e-07
AB208840-1|BAD92077.1|  830|Homo sapiens fibrillin 1 variant pro...    59   2e-07
Z26653-1|CAA81394.1| 3110|Homo sapiens laminin M chain (merosin)...    58   4e-07
U66796-1|AAB18388.1| 3110|Homo sapiens laminin alpha 2 chain pro...    58   4e-07
AL669984-2|CAI16682.1| 3122|Homo sapiens laminin, alpha 2 (meros...    58   4e-07
AL590613-1|CAH70771.1| 3122|Homo sapiens laminin, alpha 2 (meros...    58   4e-07
AL583853-1|CAH70492.1| 3122|Homo sapiens laminin, alpha 2 (meros...    58   4e-07
AL513527-1|CAI15185.1| 3122|Homo sapiens laminin, alpha 2 (meros...    58   4e-07
AL445439-1|CAH72952.1| 3122|Homo sapiens laminin, alpha 2 (meros...    58   4e-07
AL356124-1|CAI22470.1| 3122|Homo sapiens laminin, alpha 2 (meros...    58   4e-07
AY280362-1|AAP35084.1| 2386|Homo sapiens EGF domain-containing p...    58   5e-07
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein.       58   6e-07
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven...    58   6e-07
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein.           58   6e-07
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel...    58   6e-07
AL450324-2|CAI13283.1|  186|Homo sapiens protein ( Human DNA seq...    57   1e-06
BC027939-1|AAH27939.1|  600|Homo sapiens SNED1 protein protein.        56   1e-06
X62009-1|CAB56757.1|  754|Homo sapiens fibrillin 5 protein.            56   2e-06
X58531-1|CAA41418.1| 2628|Homo sapiens laminin A chain protein.        56   2e-06
AL359052-1|CAB94388.1|  112|Homo sapiens ITGBL1, integrin beta-l...    56   2e-06
AK126775-1|BAC86684.1|  952|Homo sapiens protein ( Homo sapiens ...    56   2e-06
M61951-1|AAA59486.1| 1786|Homo sapiens laminin B1 protein.             55   3e-06
M61916-1|AAA59482.1| 1786|Homo sapiens laminin B1 protein.             55   3e-06
M55370-1|AAA59485.1| 1786|Homo sapiens laminin B1 protein.             55   3e-06
D89629-1|BAB46925.1|  815|Homo sapiens cerebral protein-12 protein.    55   3e-06
D83018-1|BAA11681.1|  816|Homo sapiens nel-related protein 2 pro...    55   3e-06
BX640729-1|CAE45845.1|  674|Homo sapiens hypothetical protein pr...    55   3e-06
BC139923-1|AAI39924.1|  467|Homo sapiens Unknown (protein for MG...    55   3e-06
BC139916-1|AAI39917.1|  467|Homo sapiens Unknown (protein for MG...    55   3e-06
BC133013-1|AAI33014.1|  594|Homo sapiens EGF-like-domain, multip...    55   3e-06
BC133011-1|AAI33012.1|  594|Homo sapiens EGF-like-domain, multip...    55   3e-06
BC113455-1|AAI13456.1| 1786|Homo sapiens laminin, beta 1 protein.      55   3e-06
BC047716-1|AAH47716.1|  467|Homo sapiens ATRNL1 protein protein.       55   3e-06
BC026018-1|AAH26018.2| 1083|Homo sapiens LAMB1 protein protein.        55   3e-06
BC020544-1|AAH20544.1|  816|Homo sapiens NELL2 protein protein.        55   3e-06
AY442317-1|AAR14297.1| 1379|Homo sapiens attractin-like protein ...    55   3e-06
AY358133-1|AAQ88500.1|  594|Homo sapiens TDKS9424 protein.             55   3e-06
AL589916-3|CAM13294.1|  594|Homo sapiens EGF-like-domain, multip...    55   3e-06
AL589916-2|CAI12363.2|  619|Homo sapiens EGF-like-domain, multip...    55   3e-06
AL512304-1|CAH74015.2| 1379|Homo sapiens attractin-like 1 protein.     55   3e-06
AL392087-1|CAI40794.2| 1379|Homo sapiens attractin-like 1 protein.     55   3e-06
AL365217-4|CAM23289.1|  594|Homo sapiens EGF-like-domain, multip...    55   3e-06
AL365217-3|CAI16606.1|  619|Homo sapiens EGF-like-domain, multip...    55   3e-06
AL359813-6|CAI23221.1|  288|Homo sapiens EGF-like-domain, multip...    55   3e-06
AL357059-1|CAH70625.2| 1379|Homo sapiens attractin-like 1 protein.     55   3e-06
AL356100-1|CAI40417.2| 1379|Homo sapiens attractin-like 1 protein.     55   3e-06
AL355530-2|CAI13482.1|  476|Homo sapiens attractin-like 1 protein.     55   3e-06
AL355530-1|CAI13483.2| 1379|Homo sapiens attractin-like 1 protein.     55   3e-06
AL136322-1|CAI16644.1|  674|Homo sapiens crumbs homolog 1 (Droso...    55   3e-06
AL132767-2|CAM28320.1|  594|Homo sapiens EGF-like-domain, multip...    55   3e-06
AL132767-1|CAI22904.1|  619|Homo sapiens EGF-like-domain, multip...    55   3e-06
AL109612-2|CAM27006.1|  594|Homo sapiens EGF-like-domain, multip...    55   3e-06
AL109612-1|CAI18881.1|  619|Homo sapiens EGF-like-domain, multip...    55   3e-06
AK127277-1|BAC86914.1| 1233|Homo sapiens protein ( Homo sapiens ...    55   3e-06
AJ628247-1|CAF31639.1|  221|Homo sapiens keratin associated prot...    55   3e-06
AB126074-1|BAD20201.1|  221|Homo sapiens keratin associated prot...    55   3e-06
BC008761-1|AAH08761.2|  743|Homo sapiens LTBP3 protein protein.        55   5e-06
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.     55   5e-06
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro...    55   5e-06
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein.        54   6e-06
BC025311-1|AAH25311.1|  700|Homo sapiens hedgehog interacting pr...    54   6e-06
AY358747-1|AAQ89107.1|  700|Homo sapiens HIP protein.                  54   6e-06
AY358373-1|AAQ88739.1|  455|Homo sapiens LHPE306 protein.              54   6e-06
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g...    54   6e-06
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g...    54   6e-06
AY009951-1|AAG34731.1|  700|Homo sapiens hedgehog-interacting pr...    54   6e-06
AY009317-1|AAG35411.1|  700|Homo sapiens hedgehog-interacting pr...    54   6e-06
AK024645-1|BAB14945.1|  130|Homo sapiens protein ( Homo sapiens ...    54   6e-06
AF326471-1|AAK18182.1|  700|Homo sapiens hedgehog-interacting pr...    54   6e-06
AC008178-1|AAY24266.1|  773|Homo sapiens unknown protein.              54   6e-06
BC078143-1|AAH78143.1|  446|Homo sapiens secretory protein LOC34...    54   8e-06
BC045172-1|AAH45172.2|  749|Homo sapiens LAMB4 protein protein.        54   8e-06
AF028816-1|AAC95123.1| 1761|Homo sapiens laminin beta-4 chain pr...    54   8e-06
BC141808-1|AAI41809.1|  446|Homo sapiens LOC348174 protein protein.    54   1e-05
BC039068-1|AAH39068.1|  301|Homo sapiens MGC34761 protein protein.     54   1e-05
AK074773-1|BAC11199.1|  446|Homo sapiens protein ( Homo sapiens ...    54   1e-05
AF521893-1|AAP80866.1|  446|Homo sapiens unnamed secretory prote...    54   1e-05
BC096103-1|AAH96103.1|  763|Homo sapiens NELL1 protein protein.        53   1e-05
BC096100-1|AAH96100.1|  763|Homo sapiens NELL1 protein protein.        53   1e-05
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ...    53   2e-05
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine...    52   2e-05
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en...    52   2e-05
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var...    52   2e-05
BC035975-1|AAH35975.1|  611|Homo sapiens UMOD protein protein.         52   4e-05
AF448856-1|AAP41924.1|  303|Homo sapiens hypothetical protein pr...    52   4e-05
AY597812-1|AAT09005.1|  238|Homo sapiens UHS KerB-like protein.        51   6e-05
AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven...    51   6e-05
AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven...    51   6e-05
AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven...    51   6e-05
AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ...    51   6e-05
AB126072-1|BAD20199.1|  238|Homo sapiens keratin associated prot...    51   6e-05
AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein.                 51   6e-05
BC101705-1|AAI01706.1| 1272|Homo sapiens attractin protein.            51   7e-05
AL353193-3|CAH70472.1| 1429|Homo sapiens attractin protein.            51   7e-05
AL353193-2|CAH70471.1| 1272|Homo sapiens attractin protein.            51   7e-05
AL132773-2|CAI22616.1| 1429|Homo sapiens attractin protein.            51   7e-05
AL132773-1|CAI22614.1| 1272|Homo sapiens attractin protein.            51   7e-05
AL109805-3|CAI21878.1| 1429|Homo sapiens attractin protein.            51   7e-05
AL109805-2|CAI21876.1| 1272|Homo sapiens attractin protein.            51   7e-05
AF218915-1|AAF72881.1| 1429|Homo sapiens membrane attractin prec...    51   7e-05
AF218910-1|AAF72882.1| 1272|Homo sapiens secreted attractin prec...    51   7e-05
AL138836-3|CAC22313.2|  602|Homo sapiens multiple EGF-like-domai...    50   1e-04
Z75190-1|CAA99509.1|  699|Homo sapiens apolipoprotein E receptor...    50   1e-04
AL606760-3|CAI18909.1|  700|Homo sapiens low density lipoprotein...    50   1e-04
AL355483-3|CAI22782.1|  700|Homo sapiens low density lipoprotein...    50   1e-04
AL355357-1|CAI16435.1|   95|Homo sapiens protein ( Human DNA seq...    50   1e-04
X84900-1|CAA59325.1| 1806|Homo sapiens alpha 3B chain of laminin...    50   2e-04
X63755-1|CAA45283.1|  169|Homo sapiens high-sulpher keratin prot...    50   2e-04
BC053656-1|AAH53656.1|  470|Homo sapiens EDIL3 protein protein.        50   2e-04
BC009326-1|AAH09326.2|  595|Homo sapiens SCARF2 protein protein.       50   2e-04
AY327116-1|AAQ72571.1| 3277|Homo sapiens laminin alpha 3 splice ...    50   2e-04
AY327115-1|AAQ72570.1| 3333|Homo sapiens laminin alpha 3 splice ...    50   2e-04
AF428259-1|AAP97299.1|  303|Homo sapiens hypothetical protein pr...    50   2e-04
AF195420-1|AAF28318.1|  442|Homo sapiens ODZ3 protein.                 50   2e-04
AB107369-1|BAD13428.1| 3333|Homo sapiens laminin alpha 3b chain ...    50   2e-04
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ...    49   2e-04
BC077719-1|AAH77719.1|  219|Homo sapiens VWCE protein protein.         49   2e-04
BC052564-1|AAH52564.1|  219|Homo sapiens VWCE protein protein.         49   2e-04
BC042143-1|AAH42143.1|  237|Homo sapiens VWCE protein protein.         49   2e-04
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im...    49   2e-04
AL583807-2|CAH69983.1| 1587|Homo sapiens laminin, gamma 3 protein.     49   2e-04
AL583807-1|CAH69984.2| 1619|Homo sapiens laminin, gamma 3 protein.     49   2e-04
AL355872-3|CAI39529.1| 1587|Homo sapiens laminin, gamma 3 protein.     49   2e-04
AL355872-2|CAI39530.2| 1619|Homo sapiens laminin, gamma 3 protein.     49   2e-04
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i...    49   2e-04
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en...    49   2e-04
AK056571-1|BAB71219.1|  955|Homo sapiens protein ( Homo sapiens ...    49   2e-04
AF106861-1|AAD03057.1| 1272|Homo sapiens attractin-2 protein.          49   2e-04
AB208887-1|BAD92124.1| 1379|Homo sapiens laminin, gamma 3 precur...    49   3e-04
X85108-1|CAA59429.1| 1331|Homo sapiens alpha3b subunit of lamini...    48   4e-04
BC119643-1|AAI19644.1|  370|Homo sapiens keratin associated prot...    48   4e-04
AL354836-5|CAC22310.1| 3690|Homo sapiens laminin, alpha 5 protein.     48   4e-04
AF443072-1|AAM12527.1| 3695|Homo sapiens laminin alpha5 chain pr...    48   4e-04
AB126076-1|BAD20203.1|  165|Homo sapiens keratin associated prot...    48   4e-04
AB076354-1|BAD01541.1|  370|Homo sapiens keratin associated prot...    48   4e-04
AB067494-1|BAB67800.1| 1737|Homo sapiens KIAA1907 protein protein.     48   4e-04
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F...    48   5e-04
X55293-1|CAA39005.1|  169|Homo sapiens ultra high-sulphur kerati...    48   5e-04
M59303-1|AAA36499.1|  320|Homo sapiens protein Z protein.              48   5e-04
M55671-1|AAA36501.1|  422|Homo sapiens protein Z protein.              48   5e-04
M55670-1|AAA36500.1|  400|Homo sapiens protein Z protein.              48   5e-04
BC101744-1|AAI01745.2|  169|Homo sapiens keratin associated prot...    48   5e-04
BC074907-1|AAH74907.1|  400|Homo sapiens protein Z, vitamin K-de...    48   5e-04
BC074906-1|AAH74906.1|  400|Homo sapiens protein Z, vitamin K-de...    48   5e-04
BC069531-1|AAH69531.1|  169|Homo sapiens keratin associated prot...    48   5e-04
AL137002-16|CAI41389.1|  422|Homo sapiens protein Z, vitamin K-d...    48   5e-04
AL137002-15|CAI41388.1|  400|Homo sapiens protein Z, vitamin K-d...    48   5e-04
AJ006693-1|CAA07189.1|  169|Homo sapiens ultra high sulfer kerat...    48   5e-04
AF440358-1|AAL27631.1|  400|Homo sapiens protein Z, vitamin K-de...    48   5e-04
AB126078-1|BAD20205.1|  169|Homo sapiens keratin associated prot...    48   5e-04
AB126073-1|BAD20200.1|  288|Homo sapiens keratin associated prot...    48   5e-04
AB033749-2|BAA85764.1|  422|Homo sapiens protein Z spliced varia...    48   5e-04
AB033749-1|BAA85763.1|  400|Homo sapiens protein Z protein.            48   5e-04
U70312-1|AAC02648.1|  480|Homo sapiens integrin binding protein ...    48   7e-04
BC030828-1|AAH30828.1|  480|Homo sapiens EGF-like repeats and di...    48   7e-04
AY358363-1|AAQ88729.1|  420|Homo sapiens CRELD1 protein.               48   7e-04
AF452623-1|AAM75206.1|  420|Homo sapiens cysteine-rich with EGF-...    48   7e-04
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.       47   0.001
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt...    47   0.001
BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro...    47   0.001
AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro...    47   0.001
X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA ...    47   0.001
U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein ...    47   0.001
U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate prote...    47   0.001
J02814-1|AAA36437.1|  688|Homo sapiens protein ( Human chondroit...    47   0.001
D32039-1|BAA06801.1|  655|Homo sapiens proteoglycan PG-M(V3) pro...    47   0.001
BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein pr...    47   0.001
AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate pro...    47   0.001
S77512-1|AAB34682.2| 1798|Homo sapiens laminin beta 2 chain prot...    46   0.002
BC132765-1|AAI32766.1|  832|Homo sapiens ADAM metallopeptidase d...    46   0.002
BC132763-1|AAI32764.1|  832|Homo sapiens ADAM metallopeptidase d...    46   0.002
AJ005580-1|CAC20565.1|  832|Homo sapiens Adam23 protein protein.       46   0.002
AC010731-1|AAY14948.1|  179|Homo sapiens unknown protein.              46   0.002
AB076353-1|BAD01540.1|  365|Homo sapiens keratin associated prot...    46   0.002
AB076351-1|BAD01538.1|  401|Homo sapiens keratin associated prot...    46   0.002
AB009672-1|BAA32351.1|  832|Homo sapiens MDC3 protein.                 46   0.002
Z68155-1|CAA92279.1| 1798|Homo sapiens laminin beta 2 chain prot...    46   0.002
X62008-1|CAB56534.1|  517|Homo sapiens fibrillin 15 protein.           46   0.002
M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein.       46   0.002
J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein.                  46   0.002
CR457380-1|CAG33661.1|  422|Homo sapiens CRELD1 protein.               46   0.002
BC050675-1|AAH50675.1|  353|Homo sapiens cysteine-rich with EGF-...    46   0.002
BC008720-1|AAH08720.1|  422|Homo sapiens cysteine-rich with EGF-...    46   0.002
AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein.       46   0.002
AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (forme...    46   0.002

>AB040888-1|BAA95979.2| 2450|Homo sapiens KIAA1455 protein protein.
          Length = 2450

 Score = 1257 bits (3115), Expect = 0.0
 Identities = 654/1847 (35%), Positives = 1026/1847 (55%), Gaps = 63/1847 (3%)

Query: 760  QITLGEKLSKEIPPYSYWNMQFYQSQSSYVNFDYLIPRGASIGVYARRNALPTHTQYNFL 819
            ++ +G +  +EIPP  +W  Q +  Q  ++ F+  + + A IGVY R+   P+HTQY+F+
Sbjct: 138  ELDIGRRAIQEIPPGIFWRSQLFIDQPQFLKFNISLQKDALIGVYGRKGLPPSHTQYDFV 197

Query: 820  EVLTGFK--ARTTRASYPSVK-----KEVT-------HYMEQGPWFLSLYNDDGDPQEIS 865
            E+L G +  AR  R+   + +     + V+        Y++ G W L+ YND  + +++S
Sbjct: 198  ELLDGSRLIAREQRSLLETERAGRQARSVSLHEAGFIQYLDSGIWHLAFYNDGKNAEQVS 257

Query: 866  FVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            F  +V E +   CP  C G GEC+ G C C PGF G DCS++ CPVLCS  G+Y  G C 
Sbjct: 258  FNTIVIESVV-ECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCL 316

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C  GWKG EC +   +C  P C G G C+ G C+C  GYKG+ C E DC  P CS HG C
Sbjct: 317  CFSGWKGTECDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVC 376

Query: 986  IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCS 1045
            I G C C  GW G++C  +      C   CSGHGT+  ++ +C+C   W+G DCS E+CS
Sbjct: 377  IHGECHCSPGWGGSNCEIL---KTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICS 433

Query: 1046 LECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEG 1105
            ++CG HG C+G +C C  GW+G  C+ R C  RCAEHG CK+G C C  GWNG HCT+EG
Sbjct: 434  VDCGSHGVCMGGTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEG 493

Query: 1106 CPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECC 1165
            CP  C  +G+C +D +G W C C  GW G  C    E +C DS+DN+ DGL+DC DP+CC
Sbjct: 494  CPGLCNSNGRCTLDQNG-WHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDCMDPDCC 552

Query: 1166 QSPACKSSQLCVSSPKPTDILLRK-QPPAITA--SFFERMKFLIDEGSLQNYAKQETFNE 1222
               +C++   C   P P DI+ +  Q P+  A  SF++R+ FLI   S      +  FN+
Sbjct: 553  LQSSCQNQPYCRGLPDPQDIISQSLQSPSQQAAKSFYDRISFLIGSDSTHVIPGESPFNK 612

Query: 1223 SRSAVIRGRVITTLGSGLVGVRVS-TSTPLEGFTLTREDGWFDLLVNGGGAVTLHFGRSP 1281
            S ++VIRG+V+T  G+ L+GV VS    P  G+T+TR+DG FDL+ NGG ++TL F RSP
Sbjct: 613  SLASVIRGQVLTADGTPLIGVNVSFFHYPEYGYTITRQDGMFDLVANGGASLTLVFERSP 672

Query: 1282 FKRSTQVVFVPWNXXXXXXXXXMTTADEKTGMGPPQACLAHDYDMMKPVVLATWKHGFQG 1341
            F      V++PWN         M T   K       +C    +    P+++++    F  
Sbjct: 673  FLTQYHTVWIPWN-----VFYVMDTLVMKKEENDIPSCDLSGFVRPNPIIVSSPLSTFFR 727

Query: 1342 ACPDKSAILAESQVVQESLQIPGTGLNLVYHSSRAAGYLSTIQLQLTPEIVPPTLALIHL 1401
            + P+ S I+ E+QV+ E   IPGT L L Y SSRAAGY S +++ +T  I+P  L  +HL
Sbjct: 728  SSPEDSPIIPETQVLHEETTIPGTDLKLSYLSSRAAGYKSVLKITMTQSIIPFNLMKVHL 787

Query: 1402 RITIEGILFEKTFEADPIIKFTYSWNRLNVYRQRVYGVTTALVKVGYQYTDCKDI-IWNV 1460
             + + G LF+K F A P + +T+ W++ + Y Q+VYG++ A+V VGY+Y  C D+ +W  
Sbjct: 788  MVAVVGRLFQKWFPASPNLAYTFIWDKTDAYNQKVYGLSEAVVSVGYEYESCLDLTLWEK 847

Query: 1461 QTTKLSGHDMSISDVGGWNLDIHHRYNFHEGILQKGDGTNIYLKHKPRLIITTMGDGRQR 1520
            +T  L G+++  S++GGW LD HH  +   GIL KG+G N ++  +P ++ + MG+GR+R
Sbjct: 848  RTAILQGYELDASNMGGWTLDKHHVLDVQNGILYKGNGENQFISQQPPVVSSIMGNGRRR 907

Query: 1521 KLECGSECIGPATKQRXXXXXXXXXXXDGSIFVGDFNLVRKINTDGTVRTLVKLNATRVS 1580
             + C S C G A   +           DGS++VGDFN VR+I   G V ++++L ++  +
Sbjct: 908  SISCPS-CNGQADGNKLLAPVALACGIDGSLYVGDFNYVRRIFPSGNVTSVLEL-SSNPA 965

Query: 1581 YRYHMALSPLDGTLYISDPESHQIIKVHNTEDFSDPEHNWETVVGSGERCLPGDEAHCGD 1640
            +RY++A  P+ G LY+SD  + +I +  +     D   N E V G+GE+CLP DEA CGD
Sbjct: 966  HRYYLATDPVTGDLYVSDTNTRRIYRPKSLTGAKDLTKNAEVVAGTGEQCLPFDEARCGD 1025

Query: 1641 GALARDAKLAYPKGVAVSVDNVVYFADGTNIRMVDRDGIITTVIGNHMHRAHWKPIPCEG 1700
            G  A +A L  PKG+AV  + ++YF DGT IR VD++GII+T++G++      +P+ C+ 
Sbjct: 1026 GGKAVEATLMSPKGMAVDKNGLIYFVDGTMIRKVDQNGIISTLLGSN-DLTSARPLTCDT 1084

Query: 1701 TLSVEEVHLRWPTELAINPLDNSLHIIDDHMILQMAPDGRVKVIAGRPLHCPAPVSGYDM 1760
            ++ + +V L WPT+LAINP+DNS++++D++++LQ+  + +V++ AGRP+HC  P   Y +
Sbjct: 1085 SMHISQVRLEWPTDLAINPMDNSIYVLDNNVVLQITENRQVRIAAGRPMHCQVPGVEYPV 1144

Query: 1761 -ELATYATLVMPQSIAFGAAGDLYVAESDSQRINRVRLITTDGKISLYAGAESKCNCL-E 1818
             + A   TL    +IA   +G LY+ E+D ++INR+R +TTDG+ISL AG  S+C+C  +
Sbjct: 1145 GKHAVQTTLESATAIAVSYSGVLYITETDEKKINRIRQVTTDGEISLVAGIPSECDCKND 1204

Query: 1819 RGCDCFEADHFLASNSKFNTISAVVVSPDGIVHIADQANYRIRSVMASIPDASGTREYEI 1878
              CDC+++    A ++K +  S++  SPDG ++IAD  N RIR+V  + P  +    YE+
Sbjct: 1205 ANCDCYQSGDGYAKDAKLSAPSSLAASPDGTLYIADLGNIRIRAVSKNKPLLNSMNFYEV 1264

Query: 1879 YSPDTQEIYIFNRFGQHVMTKNILTGEDNYVFTYTVNTRNGKLSTVTDAAGNKVFLLRDY 1938
             SP  QE+YIF+  G H  T +++TG+  Y F+Y   + +  ++ VTD+ GN + + RD 
Sbjct: 1265 ASPTDQELYIFDINGTHQYTVSLVTGDYLYNFSY---SNDNDITAVTDSNGNTLRIRRDP 1321

Query: 1939 SSLVNSIENTKGQKCRLKMSRMKMLQELRTPDNFNVTFDYHRTTGLLKSKYDSTGRSYIY 1998
            + +   + +   Q   L +     L+ +       V F YH  +GLL +K D TG +  +
Sbjct: 1322 NRMPVRVVSPDNQVIWLTIGTNGCLKSMTAQGLELVLFTYHGNSGLLATKSDETGWTTFF 1381

Query: 1999 NYDECGRLTSAVTPTGRIINLTFDLGLKGAIVRVSENNRKPVSILIKGSSVNTKIGEAEK 2058
            +YD  GRLT+   PTG + NL  D+     +   S +  + VSI    SS+++     + 
Sbjct: 1382 DYDSEGRLTNVTFPTGVVTNLHGDMDKAITVDIESSSREEDVSITSNLSSIDSFYTMVQD 1441

Query: 2059 KXXXXXXXXXXXXMPWGHVISTDTVPYTILAEIDPILGESYPVPAKQGTEVGGDLA-NRF 2117
            +            +    +I    +      E   + G + P  AK+   + G+   N  
Sbjct: 1442 QLRNSYQIGYDGSL---RIIYASGLDSHYQTEPHVLAGTANPTVAKRNMTLPGENGQNLV 1498

Query: 2118 EWRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVAVFMDDKYELLNVT 2177
            EWR+   R   ++GK    V   GRKLRVNG NLL++++DR T T  ++ D +  LL + 
Sbjct: 1499 EWRF---RKEQAQGK----VNVFGRKLRVNGRNLLSVDFDRTTKTEKIYDDHRKFLLRIA 1551

Query: 2178 YDRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRAGRLHEIRYGDGSS 2237
            YD +  P  W P S + + V + Y    ++     G  +E   +D  GR+    + DG +
Sbjct: 1552 YDTSGHPTLWLPSSKLMA-VNVTYSSTGQIASIQRGTTSEKVDYDGQGRIVSRVFADGKT 1610

Query: 2238 LAYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTFALMTSLGYFKYQY 2297
             +Y++ +   S+ L + + R   Y+ +YD    L  +T P    HT   + S+GY++  Y
Sbjct: 1611 WSYTYLE--KSMVLLLHSQR--QYIFEYDMWDRLSAITMPSVARHTMQTIRSIGYYRNIY 1666

Query: 2298 FSPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAGASAIRYVYHDNTH 2357
              P +       YN++G +L   F   S ++L+ Y    +L  +L  ++ + + Y +   
Sbjct: 1667 NPPESNASIITDYNEEGLLLQTAFLGTSRRVLFKYRRQTRLSEILYDSTRVSFTYDETAG 1726

Query: 2358 LVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQYDGNARLSTIDVNI 2417
            ++K V +    +     Y+   G L D ++   S+ G+ NA F Y YD + R++++   I
Sbjct: 1727 VLKTVNLQSDGFICTIRYR-QIGPLIDRQIFRFSEDGMVNARFDYSYDNSFRVTSMQGVI 1785

Query: 2418 NSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTITDYDDHGRIKTFL 2477
            N   +P    +++   G +E      +     N+ +   T+   +T   +D HGRIK   
Sbjct: 1786 NETPLPIDLYQFDDISGKVEQFGKFGVIYYDINQII--STAVMTYT-KHFDAHGRIKEIQ 1842

Query: 2478 INIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHLMEVVGSEDDL-KY 2534
              I    ++ + ++YD   R+  +++ IG  A + + +Y Y  DG L  V  +E  + +Y
Sbjct: 1843 YEIFRSLMYWITIQYDNMGRVTKREIKIGPFANTTKYAYEYDVDGQLQTVYLNEKIMWRY 1902

Query: 2535 NYDENGNVIGIIEHGEKRY--LGYDIGDRVVQYGDVEFSSYDGRGFV 2579
            NYD NGN+  +      R   L YD+ DR+ + GDV++   D  GF+
Sbjct: 1903 NYDLNGNLHLLNPSNSARLTPLRYDLRDRITRLGDVQY-RLDEDGFL 1948



 Score =  171 bits (417), Expect = 2e-41
 Identities = 121/387 (31%), Positives = 194/387 (50%), Gaps = 19/387 (4%)

Query: 2580 GDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNTNLIYLENRLYDPVVGQWMTPSW 2639
            G ++K+I+ + +G+I  DSN  F + + FHGG++D  T LI+   R YD + G+W TP  
Sbjct: 2061 GLMLKQIQYTAYGEIYFDSNIDFQLVIGFHGGLYDPLTKLIHFGERDYDILAGRWTTPDI 2120

Query: 2640 EHLATKLSLPTDIFIYRFKNNDPINKQQNVP-YMTSLNSWLQLYGYDL-NKMMGSKYIND 2697
            E        P    +Y F+NN+P +K  +V  Y+T +NSWL  +G+ L N + G      
Sbjct: 2121 EIWKRIGKDPAPFNLYMFRNNNPASKIHDVKDYITDVNSWLVTFGFHLHNAIPGFPVPKF 2180

Query: 2698 MIFQPMTSVTAAQLAPDFGVMSGLQC-IIEKVNDKLSDIEFVPTPLLKMEPITRNLLPRV 2756
             + +P   +  +Q   D   + G+Q  +  +    LS  +     + +            
Sbjct: 2181 DLTEPSYELVKSQQWDDIPPIFGVQQQVARQAKAFLSLGKMAEVQVSRRRAGGAQSWLWF 2240

Query: 2757 SYKRGVFGEGVLISRVDGRAFISVADGANSVVEDVI--TTVFNNSYFLD-VHFSIHDQDV 2813
            +  + + G+GV+++   GR   +V + AN   ED I    V NN+++L+ +HF+I  +D 
Sbjct: 2241 ATVKSLIGKGVMLAVSQGRVQTNVLNIAN---EDCIKVAAVLNNAFYLENLHFTIEGKDT 2297

Query: 2814 FYFVKDNSLKIRDDMEELRRLSGK--------FNVSQDETNDQGLEVRVHAVGKGSAQAV 2865
             YF+K  + +   D+  LR  SG+          VSQ  T   G   R   V        
Sbjct: 2298 HYFIKTTTPE--SDLGTLRLTSGRKALENGINVTVSQSTTVVNGRTRRFADVEMQFGALA 2355

Query: 2866 IVLRYGVDPAQERIKLLKHAHKRAATRAWEREKALVAAGWEGRGSWTEEEKEELISHGIV 2925
            + +RYG+   +E+ ++L+ A +RA  RAW RE+  V  G EG   WTE EK +L+S G V
Sbjct: 2356 LHVRYGMTLDEEKARILEQARQRALARAWAREQQRVRDGEEGARLWTEGEKRQLLSAGKV 2415

Query: 2926 DGWAARDVHSISKYPQLADDPANIVFV 2952
             G+    V S+ +YP+LAD   NI F+
Sbjct: 2416 QGYDGYYVLSVEQYPELADSANNIQFL 2442


>Z85995-1|CAI42721.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
            1(Drosophila) protein.
          Length = 2725

 Score = 1199 bits (2969), Expect = 0.0
 Identities = 632/1861 (33%), Positives = 1006/1861 (54%), Gaps = 84/1861 (4%)

Query: 760  QITLGEKLSKEIPPYSYWNMQFYQSQSSYVNFDYLIPRGASIGVYARRNALPTHTQYNFL 819
            ++ +G ++ + IPP  +W  Q       Y+ F+  + + + +G+Y RRN  PTHTQ++F+
Sbjct: 401  EVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFV 460

Query: 820  EVLTGFKA--RTTRAS-----------YPSVKKE-VTHYMEQGPWFLSLYNDDGDPQEIS 865
            +++ G +   + ++ S             S+++     YM+QGPW+L+ YND G   E  
Sbjct: 461  KLMDGKQLVKQDSKGSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYND-GKKMEQV 519

Query: 866  FVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            FV   A E+  +C   C+G GEC+ GHC C PGF G DC++  CPVLC   GEY  G C 
Sbjct: 520  FVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCV 579

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C  GWKG EC +  ++C  P C GHG C+ G C CV GYKG+ C E DC  P CS HG C
Sbjct: 580  CRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGIC 639

Query: 986  IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCS 1045
            ++G C C  GW G +C T       C   CSGHGTF +D   CSC  KW+G DCS E+C+
Sbjct: 640  VKGECHCSTGWGGVNCET---PLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCT 696

Query: 1046 LECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL-- 1103
            +ECG HG C    C C  GW G  C  R C + C EHGQCK+G C C  GW G HCT+  
Sbjct: 697  MECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAH 756

Query: 1104 ------EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLV 1157
                  +GCP  C G+G+C +D +G W C C  GW G  C  + E +C D+ DND DGL 
Sbjct: 757  YLDAVRDGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLT 815

Query: 1158 DCEDPECCQSPACKSSQLCVSSPKPTDILLRKQ---PPAITASFFERMKFLIDEGSLQNY 1214
            DC DP+CCQ   C  S LC  SP P D++ + Q       +  F++R+KFLI + S    
Sbjct: 816  DCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVI 875

Query: 1215 AKQETFNESRSAVIRGRVITTLGSGLVGVRVSTSTPLE-GFTLTREDGWFDLLVNGGGAV 1273
              + +F+  R+ VIRG+V+   G+ LVGV VS     + GFT++R+DG FDL+  GG +V
Sbjct: 876  PPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISV 935

Query: 1274 TLHFGRSPFKRSTQVVFVPWNXXXXXXXXXMTTADEKTGMGPPQACLAHDYDMMKPVVLA 1333
             L F RSPF    + +++PWN         M        +  P +C   ++    P+VL 
Sbjct: 936  ILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRV-----VSDPPSCDISNFISPNPIVLP 990

Query: 1334 TWKHGFQGACPDKSAILAESQVVQESLQIPGTGLNLVYHSSRAAGYLSTIQLQLTPEIVP 1393
            +    F G+CP++  I+ E QVVQE + IP + + L Y SSR  GY + +++ LT   +P
Sbjct: 991  SPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIP 1050

Query: 1394 PTLALIHLRITIEGILFEKTFEADPIIKFTYSWNRLNVYRQRVYGVTTALVKVGYQYTDC 1453
              +  +HL + +EG L +K F A   + +T++WN+ ++Y Q+V+G+  ALV VGY+Y  C
Sbjct: 1051 VGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETC 1110

Query: 1454 KD-IIWNVQTTKLSGHDMSISDVGGWNLDIHHRYNFHEGILQKGDGTNIYLKHKPRLIIT 1512
             D I+W  +T  L G +M  S++GGW+L+ HH  N   GI+ KG+G N+++  +P +I T
Sbjct: 1111 PDFILWEQRTVVLQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVIST 1170

Query: 1513 TMGDGRQRKLECGSECIGPATKQRXXXXXXXXXXXDGSIFVGDFNLVRKINTDGTVRTLV 1572
             MG+G QR + C + C GPA   +           DGS++VGDFN VR+I   G   +++
Sbjct: 1171 IMGNGHQRSVAC-TNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSIL 1229

Query: 1573 KLNATRVSYRYHMALSPLDGTLYISDPESHQIIKVHNTEDFSDPEHNWETVVGSGERCLP 1632
            +L +T  +++Y++A+ P+  +LY+SD  + ++ K+ +  +  D   N+E V G+G++CLP
Sbjct: 1230 EL-STSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLP 1288

Query: 1633 GDEAHCGDGALARDAKLAYPKGVAVSVDNVVYFADGTNIRMVDRDGIITTVIGNHMHRAH 1692
             D++HCGDG  A +A L  P+G+ V     +YF DGT IR +D + +ITTVIG++     
Sbjct: 1289 FDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSN-GLTS 1347

Query: 1693 WKPIPCEGTLSVEEVHLRWPTELAINPLDNSLHIIDDHMILQMAPDGRVKVIAGRPLHCP 1752
             +P+ C+  + + +V L WPT+LA+NP+DNSL+++D++++LQ++ + RV++IAGRP+HC 
Sbjct: 1348 TQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQ 1407

Query: 1753 APVSGYDM--ELATYATLVMPQSIAFGAAGDLYVAESDSQRINRVRLITTDGKISLYAGA 1810
             P   + +  ++A ++TL   ++I+   +G L++AE+D +++NR++ +TT+G+I + AGA
Sbjct: 1408 VPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGA 1467

Query: 1811 ESKCNC-LERGCDCFEADHFLASNSKFNTISAVVVSPDGIVHIADQANYRIRSVMASIPD 1869
             + C+C ++  CDCF  D   A ++K    S++ VSPDG +++AD  N RIR++  +   
Sbjct: 1468 PTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAH 1527

Query: 1870 ASGTREYEIYSPDTQEIYIFNRFGQHVMTKNILTGEDNYVFTYTVNTRNGKLSTVTDAAG 1929
             +    YEI SP  QE+Y F   G H+ T N++T +  YV+ +T N+  G L  +T + G
Sbjct: 1528 LNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRD--YVYNFTYNS-EGDLGAITSSNG 1584

Query: 1930 NKVFLLRDYSSLVNSIENTKGQKCRLKMSRMKMLQELRTPDNFNVTFDYHRTTGLLKSKY 1989
            N V + RD   +   +    GQ   L +S   +L+ +           Y   TGLL +K 
Sbjct: 1585 NSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKS 1644

Query: 1990 DSTGRSYIYNYDECGRLTSAVTPTGRIINLTFDLGLKGAIVRVSENNRKPVSILIKGSSV 2049
            +  G + +Y YD  G LT+A  PTG + +   DL  K   V +  +NR+ V +    ++ 
Sbjct: 1645 NENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLE-KLTKVELDTSNRENVLMSTNLTAT 1703

Query: 2050 NT----KIGEAEKKXXXXXXXXXXXXMPWGHVISTDTVPYTILAEIDPILGE-SYPVPAK 2104
            +T    K    +                 G  I   + P+ +   ++P LG+ +  +P +
Sbjct: 1704 STIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGE 1763

Query: 2105 QGTEVGGDLANRFEWRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVA 2164
                     AN  EWR   +R   +KG     V+   R+LR +  NLL++++D  T T  
Sbjct: 1764 HN-------ANLIEWR---QRKEQNKGN----VSAFERRLRAHNRNLLSIDFDHITRTGK 1809

Query: 2165 VFMDDKYELLNVTYDRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRA 2224
            ++ D +   L + YD+T RP+ W P S  ++EV + Y     +T    G  NE   +D++
Sbjct: 1810 IYDDHRKFTLRILYDQTGRPILWSPVSR-YNEVNITYSPSGLVTFIQRGTWNEKMEYDQS 1868

Query: 2225 GRLHEIRYGDGSSLAYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTF 2284
            G++    + DG   +Y++ +   S+ L + + R   Y+ +YD    L ++T P    H+ 
Sbjct: 1869 GKIISRTWADGKIWSYTYLE--KSVMLLLHSQR--RYIFEYDQPDCLLSVTMPSMVRHSL 1924

Query: 2285 ALMTSLGYFKYQYFSPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAG 2344
              M S+GY++  Y  P +   +   Y+ DG +L  +      ++LY Y    +L  VL  
Sbjct: 1925 QTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYD 1984

Query: 2345 ASAIRYVYHDNTHLVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQY 2404
             + +   Y +++ ++K + +    +     Y+    ++     +F S+ GL NA F Y Y
Sbjct: 1985 TTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRF-SEEGLVNARFDYSY 2043

Query: 2405 DGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTI 2464
            + N R++++   IN   +P    +Y    G  E      +     N+ +     K     
Sbjct: 2044 N-NFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKH---T 2099

Query: 2465 TDYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHL 2522
              +  +G++      I     + + ++YD   R+    + +G  A   R  Y Y  DG L
Sbjct: 2100 KIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYDADGQL 2159

Query: 2523 MEV-VGSEDDLKYNYDENGNVIGIIEHGEKRY---LGYDIGDRVVQYGDVEFSSYDGRGF 2578
              V V  +   +Y+YD NGN I ++ HG+      L YD+ DR+ + G++++   D  GF
Sbjct: 2160 QTVSVNDKTQWRYSYDLNGN-INLLSHGKSARLTPLRYDLRDRITRLGEIQY-KMDEDGF 2217

Query: 2579 V 2579
            +
Sbjct: 2218 L 2218



 Score =  182 bits (444), Expect = 1e-44
 Identities = 164/593 (27%), Positives = 281/593 (47%), Gaps = 56/593 (9%)

Query: 2396 NNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQ 2455
            N   + Y+YD + +L T+ VN    +  Q R  Y+ N G++  +S  +  R T  R  ++
Sbjct: 2145 NITRYFYEYDADGQLQTVSVN----DKTQWRYSYDLN-GNINLLSHGKSARLTPLRYDLR 2199

Query: 2456 DTSKQFFTIT-DYDDHGRIKT-----FLINI-----KAFDV---FRLELEYDARNRIKTK 2501
            D   +   I    D+ G ++      F  N      KA++    + ++  YD   R    
Sbjct: 2200 DRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVAS 2259

Query: 2502 KLMIGDTA---FSERISYNYDGHLMEVVGSEDDLKYNYDENGNVIGI-IEHGEKRYLGYD 2557
            K  +G      +++  +     HL     SE    Y YD  G++I + +  GE+ Y+  D
Sbjct: 2260 KSSLGQHLQFFYADLTNPIRVTHLYNHTSSEITSLY-YDLQGHLIAMELSSGEEYYVACD 2318

Query: 2558 IGDRVVQYGDVEFSSYDGRGFVGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNT 2617
                 +      FSS       G ++KEI  +P+G I  D+ P F V + FHGG++D+ T
Sbjct: 2319 NTGTPLAV----FSSR------GQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLT 2368

Query: 2618 NLIYLENRLYDPVVGQWMTPSWEHLATKLS-LPTDIFIYRFKNNDPINKQQNV-PYMTSL 2675
             L++L  R YD V G+W TP+  H+  +L+ LP    +Y F+NN P+ K Q+V  Y T +
Sbjct: 2369 KLVHLGQRDYDVVAGRWTTPN-HHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDI 2427

Query: 2676 NSWLQLYGYDLNKMMGS----KYIN-DMIFQPMTSVTAAQLAPDFGVMSGLQCIIEKVND 2730
             SWL+L+G+ L+ ++      +  N ++ ++ +   T  Q       + G+QC ++K   
Sbjct: 2428 RSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLR 2487

Query: 2731 KLSDIEFVP-TPLLK-MEPITRNLLPRVSYKRGVFGEGVLISRVDGRAFISVADGANSVV 2788
                ++ +P TP       +     PR +    VFG+G+  +  DG     +   AN   
Sbjct: 2488 NFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDS 2547

Query: 2789 EDVITTVFNNSYFLD-VHFSIHDQDVFYFVKDNSLKIRDDMEELRRLSGK--------FN 2839
               +  + NN+++L+ +HF+I  +D  YF+K  SL+  +D+  +    G+          
Sbjct: 2548 RR-LAAILNNAHYLENLHFTIEGRDTHYFIKLGSLE--EDLVLIGNTGGRRILENGVNVT 2604

Query: 2840 VSQDETNDQGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAWEREKA 2899
            VSQ  +   G   R   +          +RYG    +E+  +L+ A +RA  +AW +E+ 
Sbjct: 2605 VSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQR 2664

Query: 2900 LVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
             +  G EG  +WTE EK++L+S G V G+    V S+ +Y +L+D   NI F+
Sbjct: 2665 RLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFM 2717


>Z83823-1|CAI42742.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
            1(Drosophila) protein.
          Length = 2725

 Score = 1199 bits (2969), Expect = 0.0
 Identities = 632/1861 (33%), Positives = 1006/1861 (54%), Gaps = 84/1861 (4%)

Query: 760  QITLGEKLSKEIPPYSYWNMQFYQSQSSYVNFDYLIPRGASIGVYARRNALPTHTQYNFL 819
            ++ +G ++ + IPP  +W  Q       Y+ F+  + + + +G+Y RRN  PTHTQ++F+
Sbjct: 401  EVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFV 460

Query: 820  EVLTGFKA--RTTRAS-----------YPSVKKE-VTHYMEQGPWFLSLYNDDGDPQEIS 865
            +++ G +   + ++ S             S+++     YM+QGPW+L+ YND G   E  
Sbjct: 461  KLMDGKQLVKQDSKGSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYND-GKKMEQV 519

Query: 866  FVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            FV   A E+  +C   C+G GEC+ GHC C PGF G DC++  CPVLC   GEY  G C 
Sbjct: 520  FVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCV 579

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C  GWKG EC +  ++C  P C GHG C+ G C CV GYKG+ C E DC  P CS HG C
Sbjct: 580  CRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGIC 639

Query: 986  IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCS 1045
            ++G C C  GW G +C T       C   CSGHGTF +D   CSC  KW+G DCS E+C+
Sbjct: 640  VKGECHCSTGWGGVNCET---PLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCT 696

Query: 1046 LECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL-- 1103
            +ECG HG C    C C  GW G  C  R C + C EHGQCK+G C C  GW G HCT+  
Sbjct: 697  MECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAH 756

Query: 1104 ------EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLV 1157
                  +GCP  C G+G+C +D +G W C C  GW G  C  + E +C D+ DND DGL 
Sbjct: 757  YLDAVRDGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLT 815

Query: 1158 DCEDPECCQSPACKSSQLCVSSPKPTDILLRKQ---PPAITASFFERMKFLIDEGSLQNY 1214
            DC DP+CCQ   C  S LC  SP P D++ + Q       +  F++R+KFLI + S    
Sbjct: 816  DCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVI 875

Query: 1215 AKQETFNESRSAVIRGRVITTLGSGLVGVRVSTSTPLE-GFTLTREDGWFDLLVNGGGAV 1273
              + +F+  R+ VIRG+V+   G+ LVGV VS     + GFT++R+DG FDL+  GG +V
Sbjct: 876  PPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISV 935

Query: 1274 TLHFGRSPFKRSTQVVFVPWNXXXXXXXXXMTTADEKTGMGPPQACLAHDYDMMKPVVLA 1333
             L F RSPF    + +++PWN         M        +  P +C   ++    P+VL 
Sbjct: 936  ILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRV-----VSDPPSCDISNFISPNPIVLP 990

Query: 1334 TWKHGFQGACPDKSAILAESQVVQESLQIPGTGLNLVYHSSRAAGYLSTIQLQLTPEIVP 1393
            +    F G+CP++  I+ E QVVQE + IP + + L Y SSR  GY + +++ LT   +P
Sbjct: 991  SPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIP 1050

Query: 1394 PTLALIHLRITIEGILFEKTFEADPIIKFTYSWNRLNVYRQRVYGVTTALVKVGYQYTDC 1453
              +  +HL + +EG L +K F A   + +T++WN+ ++Y Q+V+G+  ALV VGY+Y  C
Sbjct: 1051 VGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETC 1110

Query: 1454 KD-IIWNVQTTKLSGHDMSISDVGGWNLDIHHRYNFHEGILQKGDGTNIYLKHKPRLIIT 1512
             D I+W  +T  L G +M  S++GGW+L+ HH  N   GI+ KG+G N+++  +P +I T
Sbjct: 1111 PDFILWEQRTVVLQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVIST 1170

Query: 1513 TMGDGRQRKLECGSECIGPATKQRXXXXXXXXXXXDGSIFVGDFNLVRKINTDGTVRTLV 1572
             MG+G QR + C + C GPA   +           DGS++VGDFN VR+I   G   +++
Sbjct: 1171 IMGNGHQRSVAC-TNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSIL 1229

Query: 1573 KLNATRVSYRYHMALSPLDGTLYISDPESHQIIKVHNTEDFSDPEHNWETVVGSGERCLP 1632
            +L +T  +++Y++A+ P+  +LY+SD  + ++ K+ +  +  D   N+E V G+G++CLP
Sbjct: 1230 EL-STSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLP 1288

Query: 1633 GDEAHCGDGALARDAKLAYPKGVAVSVDNVVYFADGTNIRMVDRDGIITTVIGNHMHRAH 1692
             D++HCGDG  A +A L  P+G+ V     +YF DGT IR +D + +ITTVIG++     
Sbjct: 1289 FDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSN-GLTS 1347

Query: 1693 WKPIPCEGTLSVEEVHLRWPTELAINPLDNSLHIIDDHMILQMAPDGRVKVIAGRPLHCP 1752
             +P+ C+  + + +V L WPT+LA+NP+DNSL+++D++++LQ++ + RV++IAGRP+HC 
Sbjct: 1348 TQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQ 1407

Query: 1753 APVSGYDM--ELATYATLVMPQSIAFGAAGDLYVAESDSQRINRVRLITTDGKISLYAGA 1810
             P   + +  ++A ++TL   ++I+   +G L++AE+D +++NR++ +TT+G+I + AGA
Sbjct: 1408 VPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGA 1467

Query: 1811 ESKCNC-LERGCDCFEADHFLASNSKFNTISAVVVSPDGIVHIADQANYRIRSVMASIPD 1869
             + C+C ++  CDCF  D   A ++K    S++ VSPDG +++AD  N RIR++  +   
Sbjct: 1468 PTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAH 1527

Query: 1870 ASGTREYEIYSPDTQEIYIFNRFGQHVMTKNILTGEDNYVFTYTVNTRNGKLSTVTDAAG 1929
             +    YEI SP  QE+Y F   G H+ T N++T +  YV+ +T N+  G L  +T + G
Sbjct: 1528 LNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRD--YVYNFTYNS-EGDLGAITSSNG 1584

Query: 1930 NKVFLLRDYSSLVNSIENTKGQKCRLKMSRMKMLQELRTPDNFNVTFDYHRTTGLLKSKY 1989
            N V + RD   +   +    GQ   L +S   +L+ +           Y   TGLL +K 
Sbjct: 1585 NSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKS 1644

Query: 1990 DSTGRSYIYNYDECGRLTSAVTPTGRIINLTFDLGLKGAIVRVSENNRKPVSILIKGSSV 2049
            +  G + +Y YD  G LT+A  PTG + +   DL  K   V +  +NR+ V +    ++ 
Sbjct: 1645 NENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLE-KLTKVELDTSNRENVLMSTNLTAT 1703

Query: 2050 NT----KIGEAEKKXXXXXXXXXXXXMPWGHVISTDTVPYTILAEIDPILGE-SYPVPAK 2104
            +T    K    +                 G  I   + P+ +   ++P LG+ +  +P +
Sbjct: 1704 STIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGE 1763

Query: 2105 QGTEVGGDLANRFEWRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVA 2164
                     AN  EWR   +R   +KG     V+   R+LR +  NLL++++D  T T  
Sbjct: 1764 HN-------ANLIEWR---QRKEQNKGN----VSAFERRLRAHNRNLLSIDFDHITRTGK 1809

Query: 2165 VFMDDKYELLNVTYDRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRA 2224
            ++ D +   L + YD+T RP+ W P S  ++EV + Y     +T    G  NE   +D++
Sbjct: 1810 IYDDHRKFTLRILYDQTGRPILWSPVSR-YNEVNITYSPSGLVTFIQRGTWNEKMEYDQS 1868

Query: 2225 GRLHEIRYGDGSSLAYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTF 2284
            G++    + DG   +Y++ +   S+ L + + R   Y+ +YD    L ++T P    H+ 
Sbjct: 1869 GKIISRTWADGKIWSYTYLE--KSVMLLLHSQR--RYIFEYDQPDCLLSVTMPSMVRHSL 1924

Query: 2285 ALMTSLGYFKYQYFSPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAG 2344
              M S+GY++  Y  P +   +   Y+ DG +L  +      ++LY Y    +L  VL  
Sbjct: 1925 QTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYD 1984

Query: 2345 ASAIRYVYHDNTHLVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQY 2404
             + +   Y +++ ++K + +    +     Y+    ++     +F S+ GL NA F Y Y
Sbjct: 1985 TTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRF-SEEGLVNARFDYSY 2043

Query: 2405 DGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTI 2464
            + N R++++   IN   +P    +Y    G  E      +     N+ +     K     
Sbjct: 2044 N-NFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKH---T 2099

Query: 2465 TDYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHL 2522
              +  +G++      I     + + ++YD   R+    + +G  A   R  Y Y  DG L
Sbjct: 2100 KIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYDADGQL 2159

Query: 2523 MEV-VGSEDDLKYNYDENGNVIGIIEHGEKRY---LGYDIGDRVVQYGDVEFSSYDGRGF 2578
              V V  +   +Y+YD NGN I ++ HG+      L YD+ DR+ + G++++   D  GF
Sbjct: 2160 QTVSVNDKTQWRYSYDLNGN-INLLSHGKSARLTPLRYDLRDRITRLGEIQY-KMDEDGF 2217

Query: 2579 V 2579
            +
Sbjct: 2218 L 2218



 Score =  182 bits (444), Expect = 1e-44
 Identities = 164/593 (27%), Positives = 281/593 (47%), Gaps = 56/593 (9%)

Query: 2396 NNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQ 2455
            N   + Y+YD + +L T+ VN    +  Q R  Y+ N G++  +S  +  R T  R  ++
Sbjct: 2145 NITRYFYEYDADGQLQTVSVN----DKTQWRYSYDLN-GNINLLSHGKSARLTPLRYDLR 2199

Query: 2456 DTSKQFFTIT-DYDDHGRIKT-----FLINI-----KAFDV---FRLELEYDARNRIKTK 2501
            D   +   I    D+ G ++      F  N      KA++    + ++  YD   R    
Sbjct: 2200 DRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVAS 2259

Query: 2502 KLMIGDTA---FSERISYNYDGHLMEVVGSEDDLKYNYDENGNVIGI-IEHGEKRYLGYD 2557
            K  +G      +++  +     HL     SE    Y YD  G++I + +  GE+ Y+  D
Sbjct: 2260 KSSLGQHLQFFYADLTNPIRVTHLYNHTSSEITSLY-YDLQGHLIAMELSSGEEYYVACD 2318

Query: 2558 IGDRVVQYGDVEFSSYDGRGFVGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNT 2617
                 +      FSS       G ++KEI  +P+G I  D+ P F V + FHGG++D+ T
Sbjct: 2319 NTGTPLAV----FSSR------GQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLT 2368

Query: 2618 NLIYLENRLYDPVVGQWMTPSWEHLATKLS-LPTDIFIYRFKNNDPINKQQNV-PYMTSL 2675
             L++L  R YD V G+W TP+  H+  +L+ LP    +Y F+NN P+ K Q+V  Y T +
Sbjct: 2369 KLVHLGQRDYDVVAGRWTTPN-HHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDI 2427

Query: 2676 NSWLQLYGYDLNKMMGS----KYIN-DMIFQPMTSVTAAQLAPDFGVMSGLQCIIEKVND 2730
             SWL+L+G+ L+ ++      +  N ++ ++ +   T  Q       + G+QC ++K   
Sbjct: 2428 RSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLR 2487

Query: 2731 KLSDIEFVP-TPLLK-MEPITRNLLPRVSYKRGVFGEGVLISRVDGRAFISVADGANSVV 2788
                ++ +P TP       +     PR +    VFG+G+  +  DG     +   AN   
Sbjct: 2488 NFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDS 2547

Query: 2789 EDVITTVFNNSYFLD-VHFSIHDQDVFYFVKDNSLKIRDDMEELRRLSGK--------FN 2839
               +  + NN+++L+ +HF+I  +D  YF+K  SL+  +D+  +    G+          
Sbjct: 2548 RR-LAAILNNAHYLENLHFTIEGRDTHYFIKLGSLE--EDLVLIGNTGGRRILENGVNVT 2604

Query: 2840 VSQDETNDQGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAWEREKA 2899
            VSQ  +   G   R   +          +RYG    +E+  +L+ A +RA  +AW +E+ 
Sbjct: 2605 VSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQR 2664

Query: 2900 LVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
             +  G EG  +WTE EK++L+S G V G+    V S+ +Y +L+D   NI F+
Sbjct: 2665 RLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFM 2717


>Z81008-1|CAI42710.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
            1(Drosophila) protein.
          Length = 2725

 Score = 1199 bits (2969), Expect = 0.0
 Identities = 632/1861 (33%), Positives = 1006/1861 (54%), Gaps = 84/1861 (4%)

Query: 760  QITLGEKLSKEIPPYSYWNMQFYQSQSSYVNFDYLIPRGASIGVYARRNALPTHTQYNFL 819
            ++ +G ++ + IPP  +W  Q       Y+ F+  + + + +G+Y RRN  PTHTQ++F+
Sbjct: 401  EVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFV 460

Query: 820  EVLTGFKA--RTTRAS-----------YPSVKKE-VTHYMEQGPWFLSLYNDDGDPQEIS 865
            +++ G +   + ++ S             S+++     YM+QGPW+L+ YND G   E  
Sbjct: 461  KLMDGKQLVKQDSKGSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYND-GKKMEQV 519

Query: 866  FVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            FV   A E+  +C   C+G GEC+ GHC C PGF G DC++  CPVLC   GEY  G C 
Sbjct: 520  FVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCV 579

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C  GWKG EC +  ++C  P C GHG C+ G C CV GYKG+ C E DC  P CS HG C
Sbjct: 580  CRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGIC 639

Query: 986  IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCS 1045
            ++G C C  GW G +C T       C   CSGHGTF +D   CSC  KW+G DCS E+C+
Sbjct: 640  VKGECHCSTGWGGVNCET---PLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCT 696

Query: 1046 LECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL-- 1103
            +ECG HG C    C C  GW G  C  R C + C EHGQCK+G C C  GW G HCT+  
Sbjct: 697  MECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAH 756

Query: 1104 ------EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLV 1157
                  +GCP  C G+G+C +D +G W C C  GW G  C  + E +C D+ DND DGL 
Sbjct: 757  YLDAVRDGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLT 815

Query: 1158 DCEDPECCQSPACKSSQLCVSSPKPTDILLRKQ---PPAITASFFERMKFLIDEGSLQNY 1214
            DC DP+CCQ   C  S LC  SP P D++ + Q       +  F++R+KFLI + S    
Sbjct: 816  DCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVI 875

Query: 1215 AKQETFNESRSAVIRGRVITTLGSGLVGVRVSTSTPLE-GFTLTREDGWFDLLVNGGGAV 1273
              + +F+  R+ VIRG+V+   G+ LVGV VS     + GFT++R+DG FDL+  GG +V
Sbjct: 876  PPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISV 935

Query: 1274 TLHFGRSPFKRSTQVVFVPWNXXXXXXXXXMTTADEKTGMGPPQACLAHDYDMMKPVVLA 1333
             L F RSPF    + +++PWN         M        +  P +C   ++    P+VL 
Sbjct: 936  ILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRV-----VSDPPSCDISNFISPNPIVLP 990

Query: 1334 TWKHGFQGACPDKSAILAESQVVQESLQIPGTGLNLVYHSSRAAGYLSTIQLQLTPEIVP 1393
            +    F G+CP++  I+ E QVVQE + IP + + L Y SSR  GY + +++ LT   +P
Sbjct: 991  SPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIP 1050

Query: 1394 PTLALIHLRITIEGILFEKTFEADPIIKFTYSWNRLNVYRQRVYGVTTALVKVGYQYTDC 1453
              +  +HL + +EG L +K F A   + +T++WN+ ++Y Q+V+G+  ALV VGY+Y  C
Sbjct: 1051 VGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETC 1110

Query: 1454 KD-IIWNVQTTKLSGHDMSISDVGGWNLDIHHRYNFHEGILQKGDGTNIYLKHKPRLIIT 1512
             D I+W  +T  L G +M  S++GGW+L+ HH  N   GI+ KG+G N+++  +P +I T
Sbjct: 1111 PDFILWEQRTVVLQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVIST 1170

Query: 1513 TMGDGRQRKLECGSECIGPATKQRXXXXXXXXXXXDGSIFVGDFNLVRKINTDGTVRTLV 1572
             MG+G QR + C + C GPA   +           DGS++VGDFN VR+I   G   +++
Sbjct: 1171 IMGNGHQRSVAC-TNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSIL 1229

Query: 1573 KLNATRVSYRYHMALSPLDGTLYISDPESHQIIKVHNTEDFSDPEHNWETVVGSGERCLP 1632
            +L +T  +++Y++A+ P+  +LY+SD  + ++ K+ +  +  D   N+E V G+G++CLP
Sbjct: 1230 EL-STSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLP 1288

Query: 1633 GDEAHCGDGALARDAKLAYPKGVAVSVDNVVYFADGTNIRMVDRDGIITTVIGNHMHRAH 1692
             D++HCGDG  A +A L  P+G+ V     +YF DGT IR +D + +ITTVIG++     
Sbjct: 1289 FDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSN-GLTS 1347

Query: 1693 WKPIPCEGTLSVEEVHLRWPTELAINPLDNSLHIIDDHMILQMAPDGRVKVIAGRPLHCP 1752
             +P+ C+  + + +V L WPT+LA+NP+DNSL+++D++++LQ++ + RV++IAGRP+HC 
Sbjct: 1348 TQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQ 1407

Query: 1753 APVSGYDM--ELATYATLVMPQSIAFGAAGDLYVAESDSQRINRVRLITTDGKISLYAGA 1810
             P   + +  ++A ++TL   ++I+   +G L++AE+D +++NR++ +TT+G+I + AGA
Sbjct: 1408 VPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGA 1467

Query: 1811 ESKCNC-LERGCDCFEADHFLASNSKFNTISAVVVSPDGIVHIADQANYRIRSVMASIPD 1869
             + C+C ++  CDCF  D   A ++K    S++ VSPDG +++AD  N RIR++  +   
Sbjct: 1468 PTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAH 1527

Query: 1870 ASGTREYEIYSPDTQEIYIFNRFGQHVMTKNILTGEDNYVFTYTVNTRNGKLSTVTDAAG 1929
             +    YEI SP  QE+Y F   G H+ T N++T +  YV+ +T N+  G L  +T + G
Sbjct: 1528 LNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRD--YVYNFTYNS-EGDLGAITSSNG 1584

Query: 1930 NKVFLLRDYSSLVNSIENTKGQKCRLKMSRMKMLQELRTPDNFNVTFDYHRTTGLLKSKY 1989
            N V + RD   +   +    GQ   L +S   +L+ +           Y   TGLL +K 
Sbjct: 1585 NSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKS 1644

Query: 1990 DSTGRSYIYNYDECGRLTSAVTPTGRIINLTFDLGLKGAIVRVSENNRKPVSILIKGSSV 2049
            +  G + +Y YD  G LT+A  PTG + +   DL  K   V +  +NR+ V +    ++ 
Sbjct: 1645 NENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLE-KLTKVELDTSNRENVLMSTNLTAT 1703

Query: 2050 NT----KIGEAEKKXXXXXXXXXXXXMPWGHVISTDTVPYTILAEIDPILGE-SYPVPAK 2104
            +T    K    +                 G  I   + P+ +   ++P LG+ +  +P +
Sbjct: 1704 STIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGE 1763

Query: 2105 QGTEVGGDLANRFEWRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVA 2164
                     AN  EWR   +R   +KG     V+   R+LR +  NLL++++D  T T  
Sbjct: 1764 HN-------ANLIEWR---QRKEQNKGN----VSAFERRLRAHNRNLLSIDFDHITRTGK 1809

Query: 2165 VFMDDKYELLNVTYDRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRA 2224
            ++ D +   L + YD+T RP+ W P S  ++EV + Y     +T    G  NE   +D++
Sbjct: 1810 IYDDHRKFTLRILYDQTGRPILWSPVSR-YNEVNITYSPSGLVTFIQRGTWNEKMEYDQS 1868

Query: 2225 GRLHEIRYGDGSSLAYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTF 2284
            G++    + DG   +Y++ +   S+ L + + R   Y+ +YD    L ++T P    H+ 
Sbjct: 1869 GKIISRTWADGKIWSYTYLE--KSVMLLLHSQR--RYIFEYDQPDCLLSVTMPSMVRHSL 1924

Query: 2285 ALMTSLGYFKYQYFSPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAG 2344
              M S+GY++  Y  P +   +   Y+ DG +L  +      ++LY Y    +L  VL  
Sbjct: 1925 QTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYD 1984

Query: 2345 ASAIRYVYHDNTHLVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQY 2404
             + +   Y +++ ++K + +    +     Y+    ++     +F S+ GL NA F Y Y
Sbjct: 1985 TTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRF-SEEGLVNARFDYSY 2043

Query: 2405 DGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTI 2464
            + N R++++   IN   +P    +Y    G  E      +     N+ +     K     
Sbjct: 2044 N-NFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKH---T 2099

Query: 2465 TDYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHL 2522
              +  +G++      I     + + ++YD   R+    + +G  A   R  Y Y  DG L
Sbjct: 2100 KIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYDADGQL 2159

Query: 2523 MEV-VGSEDDLKYNYDENGNVIGIIEHGEKRY---LGYDIGDRVVQYGDVEFSSYDGRGF 2578
              V V  +   +Y+YD NGN I ++ HG+      L YD+ DR+ + G++++   D  GF
Sbjct: 2160 QTVSVNDKTQWRYSYDLNGN-INLLSHGKSARLTPLRYDLRDRITRLGEIQY-KMDEDGF 2217

Query: 2579 V 2579
            +
Sbjct: 2218 L 2218



 Score =  182 bits (444), Expect = 1e-44
 Identities = 164/593 (27%), Positives = 281/593 (47%), Gaps = 56/593 (9%)

Query: 2396 NNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQ 2455
            N   + Y+YD + +L T+ VN    +  Q R  Y+ N G++  +S  +  R T  R  ++
Sbjct: 2145 NITRYFYEYDADGQLQTVSVN----DKTQWRYSYDLN-GNINLLSHGKSARLTPLRYDLR 2199

Query: 2456 DTSKQFFTIT-DYDDHGRIKT-----FLINI-----KAFDV---FRLELEYDARNRIKTK 2501
            D   +   I    D+ G ++      F  N      KA++    + ++  YD   R    
Sbjct: 2200 DRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVAS 2259

Query: 2502 KLMIGDTA---FSERISYNYDGHLMEVVGSEDDLKYNYDENGNVIGI-IEHGEKRYLGYD 2557
            K  +G      +++  +     HL     SE    Y YD  G++I + +  GE+ Y+  D
Sbjct: 2260 KSSLGQHLQFFYADLTNPIRVTHLYNHTSSEITSLY-YDLQGHLIAMELSSGEEYYVACD 2318

Query: 2558 IGDRVVQYGDVEFSSYDGRGFVGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNT 2617
                 +      FSS       G ++KEI  +P+G I  D+ P F V + FHGG++D+ T
Sbjct: 2319 NTGTPLAV----FSSR------GQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLT 2368

Query: 2618 NLIYLENRLYDPVVGQWMTPSWEHLATKLS-LPTDIFIYRFKNNDPINKQQNV-PYMTSL 2675
             L++L  R YD V G+W TP+  H+  +L+ LP    +Y F+NN P+ K Q+V  Y T +
Sbjct: 2369 KLVHLGQRDYDVVAGRWTTPN-HHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDI 2427

Query: 2676 NSWLQLYGYDLNKMMGS----KYIN-DMIFQPMTSVTAAQLAPDFGVMSGLQCIIEKVND 2730
             SWL+L+G+ L+ ++      +  N ++ ++ +   T  Q       + G+QC ++K   
Sbjct: 2428 RSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLR 2487

Query: 2731 KLSDIEFVP-TPLLK-MEPITRNLLPRVSYKRGVFGEGVLISRVDGRAFISVADGANSVV 2788
                ++ +P TP       +     PR +    VFG+G+  +  DG     +   AN   
Sbjct: 2488 NFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDS 2547

Query: 2789 EDVITTVFNNSYFLD-VHFSIHDQDVFYFVKDNSLKIRDDMEELRRLSGK--------FN 2839
               +  + NN+++L+ +HF+I  +D  YF+K  SL+  +D+  +    G+          
Sbjct: 2548 RR-LAAILNNAHYLENLHFTIEGRDTHYFIKLGSLE--EDLVLIGNTGGRRILENGVNVT 2604

Query: 2840 VSQDETNDQGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAWEREKA 2899
            VSQ  +   G   R   +          +RYG    +E+  +L+ A +RA  +AW +E+ 
Sbjct: 2605 VSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQR 2664

Query: 2900 LVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
             +  G EG  +WTE EK++L+S G V G+    V S+ +Y +L+D   NI F+
Sbjct: 2665 RLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFM 2717


>AL031075-1|CAI43065.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
            1(Drosophila) protein.
          Length = 2725

 Score = 1199 bits (2969), Expect = 0.0
 Identities = 632/1861 (33%), Positives = 1006/1861 (54%), Gaps = 84/1861 (4%)

Query: 760  QITLGEKLSKEIPPYSYWNMQFYQSQSSYVNFDYLIPRGASIGVYARRNALPTHTQYNFL 819
            ++ +G ++ + IPP  +W  Q       Y+ F+  + + + +G+Y RRN  PTHTQ++F+
Sbjct: 401  EVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFV 460

Query: 820  EVLTGFKA--RTTRAS-----------YPSVKKE-VTHYMEQGPWFLSLYNDDGDPQEIS 865
            +++ G +   + ++ S             S+++     YM+QGPW+L+ YND G   E  
Sbjct: 461  KLMDGKQLVKQDSKGSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYND-GKKMEQV 519

Query: 866  FVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            FV   A E+  +C   C+G GEC+ GHC C PGF G DC++  CPVLC   GEY  G C 
Sbjct: 520  FVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCV 579

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C  GWKG EC +  ++C  P C GHG C+ G C CV GYKG+ C E DC  P CS HG C
Sbjct: 580  CRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGIC 639

Query: 986  IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCS 1045
            ++G C C  GW G +C T       C   CSGHGTF +D   CSC  KW+G DCS E+C+
Sbjct: 640  VKGECHCSTGWGGVNCET---PLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCT 696

Query: 1046 LECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL-- 1103
            +ECG HG C    C C  GW G  C  R C + C EHGQCK+G C C  GW G HCT+  
Sbjct: 697  MECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAH 756

Query: 1104 ------EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLV 1157
                  +GCP  C G+G+C +D +G W C C  GW G  C  + E +C D+ DND DGL 
Sbjct: 757  YLDAVRDGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLT 815

Query: 1158 DCEDPECCQSPACKSSQLCVSSPKPTDILLRKQ---PPAITASFFERMKFLIDEGSLQNY 1214
            DC DP+CCQ   C  S LC  SP P D++ + Q       +  F++R+KFLI + S    
Sbjct: 816  DCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVI 875

Query: 1215 AKQETFNESRSAVIRGRVITTLGSGLVGVRVSTSTPLE-GFTLTREDGWFDLLVNGGGAV 1273
              + +F+  R+ VIRG+V+   G+ LVGV VS     + GFT++R+DG FDL+  GG +V
Sbjct: 876  PPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISV 935

Query: 1274 TLHFGRSPFKRSTQVVFVPWNXXXXXXXXXMTTADEKTGMGPPQACLAHDYDMMKPVVLA 1333
             L F RSPF    + +++PWN         M        +  P +C   ++    P+VL 
Sbjct: 936  ILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRV-----VSDPPSCDISNFISPNPIVLP 990

Query: 1334 TWKHGFQGACPDKSAILAESQVVQESLQIPGTGLNLVYHSSRAAGYLSTIQLQLTPEIVP 1393
            +    F G+CP++  I+ E QVVQE + IP + + L Y SSR  GY + +++ LT   +P
Sbjct: 991  SPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIP 1050

Query: 1394 PTLALIHLRITIEGILFEKTFEADPIIKFTYSWNRLNVYRQRVYGVTTALVKVGYQYTDC 1453
              +  +HL + +EG L +K F A   + +T++WN+ ++Y Q+V+G+  ALV VGY+Y  C
Sbjct: 1051 VGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETC 1110

Query: 1454 KD-IIWNVQTTKLSGHDMSISDVGGWNLDIHHRYNFHEGILQKGDGTNIYLKHKPRLIIT 1512
             D I+W  +T  L G +M  S++GGW+L+ HH  N   GI+ KG+G N+++  +P +I T
Sbjct: 1111 PDFILWEQRTVVLQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVIST 1170

Query: 1513 TMGDGRQRKLECGSECIGPATKQRXXXXXXXXXXXDGSIFVGDFNLVRKINTDGTVRTLV 1572
             MG+G QR + C + C GPA   +           DGS++VGDFN VR+I   G   +++
Sbjct: 1171 IMGNGHQRSVAC-TNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSIL 1229

Query: 1573 KLNATRVSYRYHMALSPLDGTLYISDPESHQIIKVHNTEDFSDPEHNWETVVGSGERCLP 1632
            +L +T  +++Y++A+ P+  +LY+SD  + ++ K+ +  +  D   N+E V G+G++CLP
Sbjct: 1230 EL-STSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLP 1288

Query: 1633 GDEAHCGDGALARDAKLAYPKGVAVSVDNVVYFADGTNIRMVDRDGIITTVIGNHMHRAH 1692
             D++HCGDG  A +A L  P+G+ V     +YF DGT IR +D + +ITTVIG++     
Sbjct: 1289 FDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSN-GLTS 1347

Query: 1693 WKPIPCEGTLSVEEVHLRWPTELAINPLDNSLHIIDDHMILQMAPDGRVKVIAGRPLHCP 1752
             +P+ C+  + + +V L WPT+LA+NP+DNSL+++D++++LQ++ + RV++IAGRP+HC 
Sbjct: 1348 TQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQ 1407

Query: 1753 APVSGYDM--ELATYATLVMPQSIAFGAAGDLYVAESDSQRINRVRLITTDGKISLYAGA 1810
             P   + +  ++A ++TL   ++I+   +G L++AE+D +++NR++ +TT+G+I + AGA
Sbjct: 1408 VPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGA 1467

Query: 1811 ESKCNC-LERGCDCFEADHFLASNSKFNTISAVVVSPDGIVHIADQANYRIRSVMASIPD 1869
             + C+C ++  CDCF  D   A ++K    S++ VSPDG +++AD  N RIR++  +   
Sbjct: 1468 PTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAH 1527

Query: 1870 ASGTREYEIYSPDTQEIYIFNRFGQHVMTKNILTGEDNYVFTYTVNTRNGKLSTVTDAAG 1929
             +    YEI SP  QE+Y F   G H+ T N++T +  YV+ +T N+  G L  +T + G
Sbjct: 1528 LNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRD--YVYNFTYNS-EGDLGAITSSNG 1584

Query: 1930 NKVFLLRDYSSLVNSIENTKGQKCRLKMSRMKMLQELRTPDNFNVTFDYHRTTGLLKSKY 1989
            N V + RD   +   +    GQ   L +S   +L+ +           Y   TGLL +K 
Sbjct: 1585 NSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKS 1644

Query: 1990 DSTGRSYIYNYDECGRLTSAVTPTGRIINLTFDLGLKGAIVRVSENNRKPVSILIKGSSV 2049
            +  G + +Y YD  G LT+A  PTG + +   DL  K   V +  +NR+ V +    ++ 
Sbjct: 1645 NENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLE-KLTKVELDTSNRENVLMSTNLTAT 1703

Query: 2050 NT----KIGEAEKKXXXXXXXXXXXXMPWGHVISTDTVPYTILAEIDPILGE-SYPVPAK 2104
            +T    K    +                 G  I   + P+ +   ++P LG+ +  +P +
Sbjct: 1704 STIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGE 1763

Query: 2105 QGTEVGGDLANRFEWRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVA 2164
                     AN  EWR   +R   +KG     V+   R+LR +  NLL++++D  T T  
Sbjct: 1764 HN-------ANLIEWR---QRKEQNKGN----VSAFERRLRAHNRNLLSIDFDHITRTGK 1809

Query: 2165 VFMDDKYELLNVTYDRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRA 2224
            ++ D +   L + YD+T RP+ W P S  ++EV + Y     +T    G  NE   +D++
Sbjct: 1810 IYDDHRKFTLRILYDQTGRPILWSPVSR-YNEVNITYSPSGLVTFIQRGTWNEKMEYDQS 1868

Query: 2225 GRLHEIRYGDGSSLAYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTF 2284
            G++    + DG   +Y++ +   S+ L + + R   Y+ +YD    L ++T P    H+ 
Sbjct: 1869 GKIISRTWADGKIWSYTYLE--KSVMLLLHSQR--RYIFEYDQPDCLLSVTMPSMVRHSL 1924

Query: 2285 ALMTSLGYFKYQYFSPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAG 2344
              M S+GY++  Y  P +   +   Y+ DG +L  +      ++LY Y    +L  VL  
Sbjct: 1925 QTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYD 1984

Query: 2345 ASAIRYVYHDNTHLVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQY 2404
             + +   Y +++ ++K + +    +     Y+    ++     +F S+ GL NA F Y Y
Sbjct: 1985 TTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRF-SEEGLVNARFDYSY 2043

Query: 2405 DGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTI 2464
            + N R++++   IN   +P    +Y    G  E      +     N+ +     K     
Sbjct: 2044 N-NFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKH---T 2099

Query: 2465 TDYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHL 2522
              +  +G++      I     + + ++YD   R+    + +G  A   R  Y Y  DG L
Sbjct: 2100 KIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYDADGQL 2159

Query: 2523 MEV-VGSEDDLKYNYDENGNVIGIIEHGEKRY---LGYDIGDRVVQYGDVEFSSYDGRGF 2578
              V V  +   +Y+YD NGN I ++ HG+      L YD+ DR+ + G++++   D  GF
Sbjct: 2160 QTVSVNDKTQWRYSYDLNGN-INLLSHGKSARLTPLRYDLRDRITRLGEIQY-KMDEDGF 2217

Query: 2579 V 2579
            +
Sbjct: 2218 L 2218



 Score =  182 bits (444), Expect = 1e-44
 Identities = 164/593 (27%), Positives = 281/593 (47%), Gaps = 56/593 (9%)

Query: 2396 NNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQ 2455
            N   + Y+YD + +L T+ VN    +  Q R  Y+ N G++  +S  +  R T  R  ++
Sbjct: 2145 NITRYFYEYDADGQLQTVSVN----DKTQWRYSYDLN-GNINLLSHGKSARLTPLRYDLR 2199

Query: 2456 DTSKQFFTIT-DYDDHGRIKT-----FLINI-----KAFDV---FRLELEYDARNRIKTK 2501
            D   +   I    D+ G ++      F  N      KA++    + ++  YD   R    
Sbjct: 2200 DRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVAS 2259

Query: 2502 KLMIGDTA---FSERISYNYDGHLMEVVGSEDDLKYNYDENGNVIGI-IEHGEKRYLGYD 2557
            K  +G      +++  +     HL     SE    Y YD  G++I + +  GE+ Y+  D
Sbjct: 2260 KSSLGQHLQFFYADLTNPIRVTHLYNHTSSEITSLY-YDLQGHLIAMELSSGEEYYVACD 2318

Query: 2558 IGDRVVQYGDVEFSSYDGRGFVGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNT 2617
                 +      FSS       G ++KEI  +P+G I  D+ P F V + FHGG++D+ T
Sbjct: 2319 NTGTPLAV----FSSR------GQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLT 2368

Query: 2618 NLIYLENRLYDPVVGQWMTPSWEHLATKLS-LPTDIFIYRFKNNDPINKQQNV-PYMTSL 2675
             L++L  R YD V G+W TP+  H+  +L+ LP    +Y F+NN P+ K Q+V  Y T +
Sbjct: 2369 KLVHLGQRDYDVVAGRWTTPN-HHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDI 2427

Query: 2676 NSWLQLYGYDLNKMMGS----KYIN-DMIFQPMTSVTAAQLAPDFGVMSGLQCIIEKVND 2730
             SWL+L+G+ L+ ++      +  N ++ ++ +   T  Q       + G+QC ++K   
Sbjct: 2428 RSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLR 2487

Query: 2731 KLSDIEFVP-TPLLK-MEPITRNLLPRVSYKRGVFGEGVLISRVDGRAFISVADGANSVV 2788
                ++ +P TP       +     PR +    VFG+G+  +  DG     +   AN   
Sbjct: 2488 NFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDS 2547

Query: 2789 EDVITTVFNNSYFLD-VHFSIHDQDVFYFVKDNSLKIRDDMEELRRLSGK--------FN 2839
               +  + NN+++L+ +HF+I  +D  YF+K  SL+  +D+  +    G+          
Sbjct: 2548 RR-LAAILNNAHYLENLHFTIEGRDTHYFIKLGSLE--EDLVLIGNTGGRRILENGVNVT 2604

Query: 2840 VSQDETNDQGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAWEREKA 2899
            VSQ  +   G   R   +          +RYG    +E+  +L+ A +RA  +AW +E+ 
Sbjct: 2605 VSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQR 2664

Query: 2900 LVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
             +  G EG  +WTE EK++L+S G V G+    V S+ +Y +L+D   NI F+
Sbjct: 2665 RLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFM 2717


>AL023878-1|CAI42975.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
            1(Drosophila) protein.
          Length = 2725

 Score = 1199 bits (2969), Expect = 0.0
 Identities = 632/1861 (33%), Positives = 1006/1861 (54%), Gaps = 84/1861 (4%)

Query: 760  QITLGEKLSKEIPPYSYWNMQFYQSQSSYVNFDYLIPRGASIGVYARRNALPTHTQYNFL 819
            ++ +G ++ + IPP  +W  Q       Y+ F+  + + + +G+Y RRN  PTHTQ++F+
Sbjct: 401  EVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFV 460

Query: 820  EVLTGFKA--RTTRAS-----------YPSVKKE-VTHYMEQGPWFLSLYNDDGDPQEIS 865
            +++ G +   + ++ S             S+++     YM+QGPW+L+ YND G   E  
Sbjct: 461  KLMDGKQLVKQDSKGSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYND-GKKMEQV 519

Query: 866  FVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            FV   A E+  +C   C+G GEC+ GHC C PGF G DC++  CPVLC   GEY  G C 
Sbjct: 520  FVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCV 579

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C  GWKG EC +  ++C  P C GHG C+ G C CV GYKG+ C E DC  P CS HG C
Sbjct: 580  CRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGIC 639

Query: 986  IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCS 1045
            ++G C C  GW G +C T       C   CSGHGTF +D   CSC  KW+G DCS E+C+
Sbjct: 640  VKGECHCSTGWGGVNCET---PLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCT 696

Query: 1046 LECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL-- 1103
            +ECG HG C    C C  GW G  C  R C + C EHGQCK+G C C  GW G HCT+  
Sbjct: 697  MECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAH 756

Query: 1104 ------EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLV 1157
                  +GCP  C G+G+C +D +G W C C  GW G  C  + E +C D+ DND DGL 
Sbjct: 757  YLDAVRDGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLT 815

Query: 1158 DCEDPECCQSPACKSSQLCVSSPKPTDILLRKQ---PPAITASFFERMKFLIDEGSLQNY 1214
            DC DP+CCQ   C  S LC  SP P D++ + Q       +  F++R+KFLI + S    
Sbjct: 816  DCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVI 875

Query: 1215 AKQETFNESRSAVIRGRVITTLGSGLVGVRVSTSTPLE-GFTLTREDGWFDLLVNGGGAV 1273
              + +F+  R+ VIRG+V+   G+ LVGV VS     + GFT++R+DG FDL+  GG +V
Sbjct: 876  PPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISV 935

Query: 1274 TLHFGRSPFKRSTQVVFVPWNXXXXXXXXXMTTADEKTGMGPPQACLAHDYDMMKPVVLA 1333
             L F RSPF    + +++PWN         M        +  P +C   ++    P+VL 
Sbjct: 936  ILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRV-----VSDPPSCDISNFISPNPIVLP 990

Query: 1334 TWKHGFQGACPDKSAILAESQVVQESLQIPGTGLNLVYHSSRAAGYLSTIQLQLTPEIVP 1393
            +    F G+CP++  I+ E QVVQE + IP + + L Y SSR  GY + +++ LT   +P
Sbjct: 991  SPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIP 1050

Query: 1394 PTLALIHLRITIEGILFEKTFEADPIIKFTYSWNRLNVYRQRVYGVTTALVKVGYQYTDC 1453
              +  +HL + +EG L +K F A   + +T++WN+ ++Y Q+V+G+  ALV VGY+Y  C
Sbjct: 1051 VGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETC 1110

Query: 1454 KD-IIWNVQTTKLSGHDMSISDVGGWNLDIHHRYNFHEGILQKGDGTNIYLKHKPRLIIT 1512
             D I+W  +T  L G +M  S++GGW+L+ HH  N   GI+ KG+G N+++  +P +I T
Sbjct: 1111 PDFILWEQRTVVLQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVIST 1170

Query: 1513 TMGDGRQRKLECGSECIGPATKQRXXXXXXXXXXXDGSIFVGDFNLVRKINTDGTVRTLV 1572
             MG+G QR + C + C GPA   +           DGS++VGDFN VR+I   G   +++
Sbjct: 1171 IMGNGHQRSVAC-TNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSIL 1229

Query: 1573 KLNATRVSYRYHMALSPLDGTLYISDPESHQIIKVHNTEDFSDPEHNWETVVGSGERCLP 1632
            +L +T  +++Y++A+ P+  +LY+SD  + ++ K+ +  +  D   N+E V G+G++CLP
Sbjct: 1230 EL-STSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLP 1288

Query: 1633 GDEAHCGDGALARDAKLAYPKGVAVSVDNVVYFADGTNIRMVDRDGIITTVIGNHMHRAH 1692
             D++HCGDG  A +A L  P+G+ V     +YF DGT IR +D + +ITTVIG++     
Sbjct: 1289 FDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSN-GLTS 1347

Query: 1693 WKPIPCEGTLSVEEVHLRWPTELAINPLDNSLHIIDDHMILQMAPDGRVKVIAGRPLHCP 1752
             +P+ C+  + + +V L WPT+LA+NP+DNSL+++D++++LQ++ + RV++IAGRP+HC 
Sbjct: 1348 TQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQ 1407

Query: 1753 APVSGYDM--ELATYATLVMPQSIAFGAAGDLYVAESDSQRINRVRLITTDGKISLYAGA 1810
             P   + +  ++A ++TL   ++I+   +G L++AE+D +++NR++ +TT+G+I + AGA
Sbjct: 1408 VPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGA 1467

Query: 1811 ESKCNC-LERGCDCFEADHFLASNSKFNTISAVVVSPDGIVHIADQANYRIRSVMASIPD 1869
             + C+C ++  CDCF  D   A ++K    S++ VSPDG +++AD  N RIR++  +   
Sbjct: 1468 PTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAH 1527

Query: 1870 ASGTREYEIYSPDTQEIYIFNRFGQHVMTKNILTGEDNYVFTYTVNTRNGKLSTVTDAAG 1929
             +    YEI SP  QE+Y F   G H+ T N++T +  YV+ +T N+  G L  +T + G
Sbjct: 1528 LNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRD--YVYNFTYNS-EGDLGAITSSNG 1584

Query: 1930 NKVFLLRDYSSLVNSIENTKGQKCRLKMSRMKMLQELRTPDNFNVTFDYHRTTGLLKSKY 1989
            N V + RD   +   +    GQ   L +S   +L+ +           Y   TGLL +K 
Sbjct: 1585 NSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKS 1644

Query: 1990 DSTGRSYIYNYDECGRLTSAVTPTGRIINLTFDLGLKGAIVRVSENNRKPVSILIKGSSV 2049
            +  G + +Y YD  G LT+A  PTG + +   DL  K   V +  +NR+ V +    ++ 
Sbjct: 1645 NENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLE-KLTKVELDTSNRENVLMSTNLTAT 1703

Query: 2050 NT----KIGEAEKKXXXXXXXXXXXXMPWGHVISTDTVPYTILAEIDPILGE-SYPVPAK 2104
            +T    K    +                 G  I   + P+ +   ++P LG+ +  +P +
Sbjct: 1704 STIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGE 1763

Query: 2105 QGTEVGGDLANRFEWRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVA 2164
                     AN  EWR   +R   +KG     V+   R+LR +  NLL++++D  T T  
Sbjct: 1764 HN-------ANLIEWR---QRKEQNKGN----VSAFERRLRAHNRNLLSIDFDHITRTGK 1809

Query: 2165 VFMDDKYELLNVTYDRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRA 2224
            ++ D +   L + YD+T RP+ W P S  ++EV + Y     +T    G  NE   +D++
Sbjct: 1810 IYDDHRKFTLRILYDQTGRPILWSPVSR-YNEVNITYSPSGLVTFIQRGTWNEKMEYDQS 1868

Query: 2225 GRLHEIRYGDGSSLAYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTF 2284
            G++    + DG   +Y++ +   S+ L + + R   Y+ +YD    L ++T P    H+ 
Sbjct: 1869 GKIISRTWADGKIWSYTYLE--KSVMLLLHSQR--RYIFEYDQPDCLLSVTMPSMVRHSL 1924

Query: 2285 ALMTSLGYFKYQYFSPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAG 2344
              M S+GY++  Y  P +   +   Y+ DG +L  +      ++LY Y    +L  VL  
Sbjct: 1925 QTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYD 1984

Query: 2345 ASAIRYVYHDNTHLVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQY 2404
             + +   Y +++ ++K + +    +     Y+    ++     +F S+ GL NA F Y Y
Sbjct: 1985 TTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRF-SEEGLVNARFDYSY 2043

Query: 2405 DGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTI 2464
            + N R++++   IN   +P    +Y    G  E      +     N+ +     K     
Sbjct: 2044 N-NFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKH---T 2099

Query: 2465 TDYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHL 2522
              +  +G++      I     + + ++YD   R+    + +G  A   R  Y Y  DG L
Sbjct: 2100 KIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYDADGQL 2159

Query: 2523 MEV-VGSEDDLKYNYDENGNVIGIIEHGEKRY---LGYDIGDRVVQYGDVEFSSYDGRGF 2578
              V V  +   +Y+YD NGN I ++ HG+      L YD+ DR+ + G++++   D  GF
Sbjct: 2160 QTVSVNDKTQWRYSYDLNGN-INLLSHGKSARLTPLRYDLRDRITRLGEIQY-KMDEDGF 2217

Query: 2579 V 2579
            +
Sbjct: 2218 L 2218



 Score =  182 bits (444), Expect = 1e-44
 Identities = 164/593 (27%), Positives = 281/593 (47%), Gaps = 56/593 (9%)

Query: 2396 NNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQ 2455
            N   + Y+YD + +L T+ VN    +  Q R  Y+ N G++  +S  +  R T  R  ++
Sbjct: 2145 NITRYFYEYDADGQLQTVSVN----DKTQWRYSYDLN-GNINLLSHGKSARLTPLRYDLR 2199

Query: 2456 DTSKQFFTIT-DYDDHGRIKT-----FLINI-----KAFDV---FRLELEYDARNRIKTK 2501
            D   +   I    D+ G ++      F  N      KA++    + ++  YD   R    
Sbjct: 2200 DRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVAS 2259

Query: 2502 KLMIGDTA---FSERISYNYDGHLMEVVGSEDDLKYNYDENGNVIGI-IEHGEKRYLGYD 2557
            K  +G      +++  +     HL     SE    Y YD  G++I + +  GE+ Y+  D
Sbjct: 2260 KSSLGQHLQFFYADLTNPIRVTHLYNHTSSEITSLY-YDLQGHLIAMELSSGEEYYVACD 2318

Query: 2558 IGDRVVQYGDVEFSSYDGRGFVGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNT 2617
                 +      FSS       G ++KEI  +P+G I  D+ P F V + FHGG++D+ T
Sbjct: 2319 NTGTPLAV----FSSR------GQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLT 2368

Query: 2618 NLIYLENRLYDPVVGQWMTPSWEHLATKLS-LPTDIFIYRFKNNDPINKQQNV-PYMTSL 2675
             L++L  R YD V G+W TP+  H+  +L+ LP    +Y F+NN P+ K Q+V  Y T +
Sbjct: 2369 KLVHLGQRDYDVVAGRWTTPN-HHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDI 2427

Query: 2676 NSWLQLYGYDLNKMMGS----KYIN-DMIFQPMTSVTAAQLAPDFGVMSGLQCIIEKVND 2730
             SWL+L+G+ L+ ++      +  N ++ ++ +   T  Q       + G+QC ++K   
Sbjct: 2428 RSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLR 2487

Query: 2731 KLSDIEFVP-TPLLK-MEPITRNLLPRVSYKRGVFGEGVLISRVDGRAFISVADGANSVV 2788
                ++ +P TP       +     PR +    VFG+G+  +  DG     +   AN   
Sbjct: 2488 NFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDS 2547

Query: 2789 EDVITTVFNNSYFLD-VHFSIHDQDVFYFVKDNSLKIRDDMEELRRLSGK--------FN 2839
               +  + NN+++L+ +HF+I  +D  YF+K  SL+  +D+  +    G+          
Sbjct: 2548 RR-LAAILNNAHYLENLHFTIEGRDTHYFIKLGSLE--EDLVLIGNTGGRRILENGVNVT 2604

Query: 2840 VSQDETNDQGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAWEREKA 2899
            VSQ  +   G   R   +          +RYG    +E+  +L+ A +RA  +AW +E+ 
Sbjct: 2605 VSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQR 2664

Query: 2900 LVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
             +  G EG  +WTE EK++L+S G V G+    V S+ +Y +L+D   NI F+
Sbjct: 2665 RLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFM 2717


>AL022718-3|CAI42154.1| 2725|Homo sapiens odz, odd Oz/ten-m homolog
            1(Drosophila) protein.
          Length = 2725

 Score = 1199 bits (2969), Expect = 0.0
 Identities = 632/1861 (33%), Positives = 1006/1861 (54%), Gaps = 84/1861 (4%)

Query: 760  QITLGEKLSKEIPPYSYWNMQFYQSQSSYVNFDYLIPRGASIGVYARRNALPTHTQYNFL 819
            ++ +G ++ + IPP  +W  Q       Y+ F+  + + + +G+Y RRN  PTHTQ++F+
Sbjct: 401  EVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFV 460

Query: 820  EVLTGFKA--RTTRAS-----------YPSVKKE-VTHYMEQGPWFLSLYNDDGDPQEIS 865
            +++ G +   + ++ S             S+++     YM+QGPW+L+ YND G   E  
Sbjct: 461  KLMDGKQLVKQDSKGSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYND-GKKMEQV 519

Query: 866  FVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            FV   A E+  +C   C+G GEC+ GHC C PGF G DC++  CPVLC   GEY  G C 
Sbjct: 520  FVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCV 579

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C  GWKG EC +  ++C  P C GHG C+ G C CV GYKG+ C E DC  P CS HG C
Sbjct: 580  CRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGIC 639

Query: 986  IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCS 1045
            ++G C C  GW G +C T       C   CSGHGTF +D   CSC  KW+G DCS E+C+
Sbjct: 640  VKGECHCSTGWGGVNCET---PLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCT 696

Query: 1046 LECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL-- 1103
            +ECG HG C    C C  GW G  C  R C + C EHGQCK+G C C  GW G HCT+  
Sbjct: 697  MECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAH 756

Query: 1104 ------EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLV 1157
                  +GCP  C G+G+C +D +G W C C  GW G  C  + E +C D+ DND DGL 
Sbjct: 757  YLDAVRDGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLT 815

Query: 1158 DCEDPECCQSPACKSSQLCVSSPKPTDILLRKQ---PPAITASFFERMKFLIDEGSLQNY 1214
            DC DP+CCQ   C  S LC  SP P D++ + Q       +  F++R+KFLI + S    
Sbjct: 816  DCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVI 875

Query: 1215 AKQETFNESRSAVIRGRVITTLGSGLVGVRVSTSTPLE-GFTLTREDGWFDLLVNGGGAV 1273
              + +F+  R+ VIRG+V+   G+ LVGV VS     + GFT++R+DG FDL+  GG +V
Sbjct: 876  PPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISV 935

Query: 1274 TLHFGRSPFKRSTQVVFVPWNXXXXXXXXXMTTADEKTGMGPPQACLAHDYDMMKPVVLA 1333
             L F RSPF    + +++PWN         M        +  P +C   ++    P+VL 
Sbjct: 936  ILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRV-----VSDPPSCDISNFISPNPIVLP 990

Query: 1334 TWKHGFQGACPDKSAILAESQVVQESLQIPGTGLNLVYHSSRAAGYLSTIQLQLTPEIVP 1393
            +    F G+CP++  I+ E QVVQE + IP + + L Y SSR  GY + +++ LT   +P
Sbjct: 991  SPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIP 1050

Query: 1394 PTLALIHLRITIEGILFEKTFEADPIIKFTYSWNRLNVYRQRVYGVTTALVKVGYQYTDC 1453
              +  +HL + +EG L +K F A   + +T++WN+ ++Y Q+V+G+  ALV VGY+Y  C
Sbjct: 1051 VGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETC 1110

Query: 1454 KD-IIWNVQTTKLSGHDMSISDVGGWNLDIHHRYNFHEGILQKGDGTNIYLKHKPRLIIT 1512
             D I+W  +T  L G +M  S++GGW+L+ HH  N   GI+ KG+G N+++  +P +I T
Sbjct: 1111 PDFILWEQRTVVLQGFEMDASNLGGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVIST 1170

Query: 1513 TMGDGRQRKLECGSECIGPATKQRXXXXXXXXXXXDGSIFVGDFNLVRKINTDGTVRTLV 1572
             MG+G QR + C + C GPA   +           DGS++VGDFN VR+I   G   +++
Sbjct: 1171 IMGNGHQRSVAC-TNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSIL 1229

Query: 1573 KLNATRVSYRYHMALSPLDGTLYISDPESHQIIKVHNTEDFSDPEHNWETVVGSGERCLP 1632
            +L +T  +++Y++A+ P+  +LY+SD  + ++ K+ +  +  D   N+E V G+G++CLP
Sbjct: 1230 EL-STSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLP 1288

Query: 1633 GDEAHCGDGALARDAKLAYPKGVAVSVDNVVYFADGTNIRMVDRDGIITTVIGNHMHRAH 1692
             D++HCGDG  A +A L  P+G+ V     +YF DGT IR +D + +ITTVIG++     
Sbjct: 1289 FDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSN-GLTS 1347

Query: 1693 WKPIPCEGTLSVEEVHLRWPTELAINPLDNSLHIIDDHMILQMAPDGRVKVIAGRPLHCP 1752
             +P+ C+  + + +V L WPT+LA+NP+DNSL+++D++++LQ++ + RV++IAGRP+HC 
Sbjct: 1348 TQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQ 1407

Query: 1753 APVSGYDM--ELATYATLVMPQSIAFGAAGDLYVAESDSQRINRVRLITTDGKISLYAGA 1810
             P   + +  ++A ++TL   ++I+   +G L++AE+D +++NR++ +TT+G+I + AGA
Sbjct: 1408 VPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGA 1467

Query: 1811 ESKCNC-LERGCDCFEADHFLASNSKFNTISAVVVSPDGIVHIADQANYRIRSVMASIPD 1869
             + C+C ++  CDCF  D   A ++K    S++ VSPDG +++AD  N RIR++  +   
Sbjct: 1468 PTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAH 1527

Query: 1870 ASGTREYEIYSPDTQEIYIFNRFGQHVMTKNILTGEDNYVFTYTVNTRNGKLSTVTDAAG 1929
             +    YEI SP  QE+Y F   G H+ T N++T +  YV+ +T N+  G L  +T + G
Sbjct: 1528 LNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRD--YVYNFTYNS-EGDLGAITSSNG 1584

Query: 1930 NKVFLLRDYSSLVNSIENTKGQKCRLKMSRMKMLQELRTPDNFNVTFDYHRTTGLLKSKY 1989
            N V + RD   +   +    GQ   L +S   +L+ +           Y   TGLL +K 
Sbjct: 1585 NSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKS 1644

Query: 1990 DSTGRSYIYNYDECGRLTSAVTPTGRIINLTFDLGLKGAIVRVSENNRKPVSILIKGSSV 2049
            +  G + +Y YD  G LT+A  PTG + +   DL  K   V +  +NR+ V +    ++ 
Sbjct: 1645 NENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLE-KLTKVELDTSNRENVLMSTNLTAT 1703

Query: 2050 NT----KIGEAEKKXXXXXXXXXXXXMPWGHVISTDTVPYTILAEIDPILGE-SYPVPAK 2104
            +T    K    +                 G  I   + P+ +   ++P LG+ +  +P +
Sbjct: 1704 STIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGE 1763

Query: 2105 QGTEVGGDLANRFEWRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVA 2164
                     AN  EWR   +R   +KG     V+   R+LR +  NLL++++D  T T  
Sbjct: 1764 HN-------ANLIEWR---QRKEQNKGN----VSAFERRLRAHNRNLLSIDFDHITRTGK 1809

Query: 2165 VFMDDKYELLNVTYDRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRA 2224
            ++ D +   L + YD+T RP+ W P S  ++EV + Y     +T    G  NE   +D++
Sbjct: 1810 IYDDHRKFTLRILYDQTGRPILWSPVSR-YNEVNITYSPSGLVTFIQRGTWNEKMEYDQS 1868

Query: 2225 GRLHEIRYGDGSSLAYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTF 2284
            G++    + DG   +Y++ +   S+ L + + R   Y+ +YD    L ++T P    H+ 
Sbjct: 1869 GKIISRTWADGKIWSYTYLE--KSVMLLLHSQR--RYIFEYDQPDCLLSVTMPSMVRHSL 1924

Query: 2285 ALMTSLGYFKYQYFSPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAG 2344
              M S+GY++  Y  P +   +   Y+ DG +L  +      ++LY Y    +L  VL  
Sbjct: 1925 QTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYD 1984

Query: 2345 ASAIRYVYHDNTHLVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQY 2404
             + +   Y +++ ++K + +    +     Y+    ++     +F S+ GL NA F Y Y
Sbjct: 1985 TTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRF-SEEGLVNARFDYSY 2043

Query: 2405 DGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTI 2464
            + N R++++   IN   +P    +Y    G  E      +     N+ +     K     
Sbjct: 2044 N-NFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKH---T 2099

Query: 2465 TDYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHL 2522
              +  +G++      I     + + ++YD   R+    + +G  A   R  Y Y  DG L
Sbjct: 2100 KIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDANITRYFYEYDADGQL 2159

Query: 2523 MEV-VGSEDDLKYNYDENGNVIGIIEHGEKRY---LGYDIGDRVVQYGDVEFSSYDGRGF 2578
              V V  +   +Y+YD NGN I ++ HG+      L YD+ DR+ + G++++   D  GF
Sbjct: 2160 QTVSVNDKTQWRYSYDLNGN-INLLSHGKSARLTPLRYDLRDRITRLGEIQY-KMDEDGF 2217

Query: 2579 V 2579
            +
Sbjct: 2218 L 2218



 Score =  182 bits (444), Expect = 1e-44
 Identities = 164/593 (27%), Positives = 281/593 (47%), Gaps = 56/593 (9%)

Query: 2396 NNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQ 2455
            N   + Y+YD + +L T+ VN    +  Q R  Y+ N G++  +S  +  R T  R  ++
Sbjct: 2145 NITRYFYEYDADGQLQTVSVN----DKTQWRYSYDLN-GNINLLSHGKSARLTPLRYDLR 2199

Query: 2456 DTSKQFFTIT-DYDDHGRIKT-----FLINI-----KAFDV---FRLELEYDARNRIKTK 2501
            D   +   I    D+ G ++      F  N      KA++    + ++  YD   R    
Sbjct: 2200 DRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVAS 2259

Query: 2502 KLMIGDTA---FSERISYNYDGHLMEVVGSEDDLKYNYDENGNVIGI-IEHGEKRYLGYD 2557
            K  +G      +++  +     HL     SE    Y YD  G++I + +  GE+ Y+  D
Sbjct: 2260 KSSLGQHLQFFYADLTNPIRVTHLYNHTSSEITSLY-YDLQGHLIAMELSSGEEYYVACD 2318

Query: 2558 IGDRVVQYGDVEFSSYDGRGFVGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNT 2617
                 +      FSS       G ++KEI  +P+G I  D+ P F V + FHGG++D+ T
Sbjct: 2319 NTGTPLAV----FSSR------GQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLT 2368

Query: 2618 NLIYLENRLYDPVVGQWMTPSWEHLATKLS-LPTDIFIYRFKNNDPINKQQNV-PYMTSL 2675
             L++L  R YD V G+W TP+  H+  +L+ LP    +Y F+NN P+ K Q+V  Y T +
Sbjct: 2369 KLVHLGQRDYDVVAGRWTTPN-HHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDI 2427

Query: 2676 NSWLQLYGYDLNKMMGS----KYIN-DMIFQPMTSVTAAQLAPDFGVMSGLQCIIEKVND 2730
             SWL+L+G+ L+ ++      +  N ++ ++ +   T  Q       + G+QC ++K   
Sbjct: 2428 RSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLR 2487

Query: 2731 KLSDIEFVP-TPLLK-MEPITRNLLPRVSYKRGVFGEGVLISRVDGRAFISVADGANSVV 2788
                ++ +P TP       +     PR +    VFG+G+  +  DG     +   AN   
Sbjct: 2488 NFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDS 2547

Query: 2789 EDVITTVFNNSYFLD-VHFSIHDQDVFYFVKDNSLKIRDDMEELRRLSGK--------FN 2839
               +  + NN+++L+ +HF+I  +D  YF+K  SL+  +D+  +    G+          
Sbjct: 2548 RR-LAAILNNAHYLENLHFTIEGRDTHYFIKLGSLE--EDLVLIGNTGGRRILENGVNVT 2604

Query: 2840 VSQDETNDQGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAWEREKA 2899
            VSQ  +   G   R   +          +RYG    +E+  +L+ A +RA  +AW +E+ 
Sbjct: 2605 VSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQR 2664

Query: 2900 LVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
             +  G EG  +WTE EK++L+S G V G+    V S+ +Y +L+D   NI F+
Sbjct: 2665 RLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFM 2717


>AF100772-1|AAF04723.1| 2725|Homo sapiens tenascin-M1 protein.
          Length = 2725

 Score = 1195 bits (2960), Expect = 0.0
 Identities = 631/1861 (33%), Positives = 1005/1861 (54%), Gaps = 84/1861 (4%)

Query: 760  QITLGEKLSKEIPPYSYWNMQFYQSQSSYVNFDYLIPRGASIGVYARRNALPTHTQYNFL 819
            ++ +G ++ + IPP  +W  Q       Y+ F+  + + + +G+Y RRN  PTHTQ++F+
Sbjct: 401  EVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFV 460

Query: 820  EVLTGFKA--RTTRAS-----------YPSVKKE-VTHYMEQGPWFLSLYNDDGDPQEIS 865
            +++ G +   + ++ S             S+++     YM+QGPW+L+ YND G   E  
Sbjct: 461  KLMDGKQLVKQDSKGSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYND-GKKMEQV 519

Query: 866  FVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            FV   A E+  +C   C+G GEC+ GHC C PGF G DC++  CPVLC   GEY  G C 
Sbjct: 520  FVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCV 579

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C  GWKG EC +  ++C  P C GHG C+ G C CV GYKG+ C E DC  P CS HG C
Sbjct: 580  CRHGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGIC 639

Query: 986  IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCS 1045
            ++G C C  GW G +C T       C   CSGHGTF +D   CSC  KW+G DCS E+C+
Sbjct: 640  VKGECHCSTGWGGVNCET---PLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCT 696

Query: 1046 LECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL-- 1103
            +ECG HG C    C C  GW G  C  R C + C EHGQCK+G C C  GW G HCT+  
Sbjct: 697  MECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAH 756

Query: 1104 ------EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLV 1157
                  +GCP  C G+G+C +D +G W C C  GW G  C  + E +C D+ DND DGL 
Sbjct: 757  YLDAVRDGCPGLCFGNGRCTLDQNG-WHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLT 815

Query: 1158 DCEDPECCQSPACKSSQLCVSSPKPTDILLRKQ---PPAITASFFERMKFLIDEGSLQNY 1214
            DC DP+CCQ   C  S LC  SP P D++ + Q       +  F++R+KFLI + S    
Sbjct: 816  DCVDPDCCQQSNCYISPLCQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVI 875

Query: 1215 AKQETFNESRSAVIRGRVITTLGSGLVGVRVSTSTPLE-GFTLTREDGWFDLLVNGGGAV 1273
              + +F+  R+ VIRG+V+   G+ LVGV VS     + GFT++R+DG FDL+  GG +V
Sbjct: 876  PPEVSFDSRRACVIRGQVVAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISV 935

Query: 1274 TLHFGRSPFKRSTQVVFVPWNXXXXXXXXXMTTADEKTGMGPPQACLAHDYDMMKPVVLA 1333
             L F RSPF    + +++PWN         M        +  P +C   ++    P+VL 
Sbjct: 936  ILIFDRSPFLPEKRTLWLPWNQFIVVEKVTMQRV-----VSDPPSCDISNFISPNPIVLP 990

Query: 1334 TWKHGFQGACPDKSAILAESQVVQESLQIPGTGLNLVYHSSRAAGYLSTIQLQLTPEIVP 1393
            +    F G+CP++  I+ E QVVQE + IP + + L Y SSR  GY + +++ LT   +P
Sbjct: 991  SPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIP 1050

Query: 1394 PTLALIHLRITIEGILFEKTFEADPIIKFTYSWNRLNVYRQRVYGVTTALVKVGYQYTDC 1453
              +  +HL + +EG L +K F A   + +T++WN+ ++Y Q+V+G+  ALV VGY+Y  C
Sbjct: 1051 VGMIKVHLTVAVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETC 1110

Query: 1454 KD-IIWNVQTTKLSGHDMSISDVGGWNLDIHHRYNFHEGILQKGDGTNIYLKHKPRLIIT 1512
             D I+W  +T  L G +M  S++G W+L+ HH  N   GI+ KG+G N+++  +P +I T
Sbjct: 1111 PDFILWEQRTVVLQGFEMDASNLGDWSLNKHHILNPQSGIIHKGNGENMFISQQPPVIST 1170

Query: 1513 TMGDGRQRKLECGSECIGPATKQRXXXXXXXXXXXDGSIFVGDFNLVRKINTDGTVRTLV 1572
             MG+G QR + C + C GPA   +           DGS++VGDFN VR+I   G   +++
Sbjct: 1171 IMGNGHQRSVAC-TNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSIL 1229

Query: 1573 KLNATRVSYRYHMALSPLDGTLYISDPESHQIIKVHNTEDFSDPEHNWETVVGSGERCLP 1632
            +L +T  +++Y++A+ P+  +LY+SD  + ++ K+ +  +  D   N+E V G+G++CLP
Sbjct: 1230 EL-STSPAHKYYLAMDPVSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLP 1288

Query: 1633 GDEAHCGDGALARDAKLAYPKGVAVSVDNVVYFADGTNIRMVDRDGIITTVIGNHMHRAH 1692
             D++HCGDG  A +A L  P+G+ V     +YF DGT IR +D + +ITTVIG++     
Sbjct: 1289 FDQSHCGDGGRASEASLNSPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSN-GLTS 1347

Query: 1693 WKPIPCEGTLSVEEVHLRWPTELAINPLDNSLHIIDDHMILQMAPDGRVKVIAGRPLHCP 1752
             +P+ C+  + + +V L WPT+LA+NP+DNSL+++D++++LQ++ + RV++IAGRP+HC 
Sbjct: 1348 TQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQ 1407

Query: 1753 APVSGYDM--ELATYATLVMPQSIAFGAAGDLYVAESDSQRINRVRLITTDGKISLYAGA 1810
             P   + +  ++A ++TL   ++I+   +G L++AE+D +++NR++ +TT+G+I + AGA
Sbjct: 1408 VPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGA 1467

Query: 1811 ESKCNC-LERGCDCFEADHFLASNSKFNTISAVVVSPDGIVHIADQANYRIRSVMASIPD 1869
             + C+C ++  CDCF  D   A ++K    S++ VSPDG +++AD  N RIR++  +   
Sbjct: 1468 PTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAH 1527

Query: 1870 ASGTREYEIYSPDTQEIYIFNRFGQHVMTKNILTGEDNYVFTYTVNTRNGKLSTVTDAAG 1929
             +    YEI SP  QE+Y F   G H+ T N++T +  YV+ +T N+  G L  +T + G
Sbjct: 1528 LNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRD--YVYNFTYNS-EGDLGAITSSNG 1584

Query: 1930 NKVFLLRDYSSLVNSIENTKGQKCRLKMSRMKMLQELRTPDNFNVTFDYHRTTGLLKSKY 1989
            N V + RD   +   +    GQ   L +S   +L+ +           Y   TGLL +K 
Sbjct: 1585 NSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNPALMTYPGNTGLLATKS 1644

Query: 1990 DSTGRSYIYNYDECGRLTSAVTPTGRIINLTFDLGLKGAIVRVSENNRKPVSILIKGSSV 2049
            +  G + +Y YD  G LT+A  PTG + +   DL  K   V +  +NR+ V +    ++ 
Sbjct: 1645 NENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLE-KLTKVELDTSNRENVLMSTNLTAT 1703

Query: 2050 NT----KIGEAEKKXXXXXXXXXXXXMPWGHVISTDTVPYTILAEIDPILGE-SYPVPAK 2104
            +T    K    +                 G  I   + P+ +   ++P LG+ +  +P +
Sbjct: 1704 STIYILKQENTQSTYRVNPDGSLRVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGE 1763

Query: 2105 QGTEVGGDLANRFEWRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVA 2164
                     AN  EWR   +R   +KG     V+   R+LR +  NLL++++D  T T  
Sbjct: 1764 HN-------ANLIEWR---QRKEQNKGN----VSAFERRLRAHNRNLLSIDFDHITRTGK 1809

Query: 2165 VFMDDKYELLNVTYDRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRA 2224
            ++ D +   L + YD+T RP+ W P S  ++EV + Y     +T    G  NE   +D++
Sbjct: 1810 IYDDHRKFTLRILYDQTGRPILWSPVSR-YNEVNITYSPSGLVTFIQRGTWNEKMEYDQS 1868

Query: 2225 GRLHEIRYGDGSSLAYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTF 2284
            G++    + DG   +Y++ +   S+ L + + R   Y+ +YD S  L ++T P    H+ 
Sbjct: 1869 GKIISRTWADGKIWSYTYLE--KSVMLLLHSQR--RYIFEYDQSDCLLSVTMPSMVRHSL 1924

Query: 2285 ALMTSLGYFKYQYFSPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAG 2344
              M S+GY++  Y  P +   +   Y+ DG +L  +      ++LY Y    +L  VL  
Sbjct: 1925 QTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEVLYD 1984

Query: 2345 ASAIRYVYHDNTHLVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQY 2404
             + +   Y +++ ++K + +    +     Y+    ++     +F S+ GL NA F Y Y
Sbjct: 1985 TTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRF-SEEGLVNARFDYSY 2043

Query: 2405 DGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTI 2464
            + N R++++   IN   +P    +Y    G  E      +     N+ +     K     
Sbjct: 2044 N-NFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKH---T 2099

Query: 2465 TDYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHL 2522
              +  +G++      I     + + ++YD   R     + +G  A   R  Y Y  DG L
Sbjct: 2100 KIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRHGNMCIRVGVDANITRYFYEYDADGQL 2159

Query: 2523 MEV-VGSEDDLKYNYDENGNVIGIIEHGEKRY---LGYDIGDRVVQYGDVEFSSYDGRGF 2578
              V V  +   +Y+YD NG+ I ++ HG+      L YD+ DR+ + G++++   D  GF
Sbjct: 2160 QTVSVNDKTQWRYSYDLNGD-INLLSHGKSARLTPLRYDLRDRITRLGEIQY-KMDEDGF 2217

Query: 2579 V 2579
            +
Sbjct: 2218 L 2218



 Score =  179 bits (436), Expect = 1e-43
 Identities = 165/593 (27%), Positives = 279/593 (47%), Gaps = 56/593 (9%)

Query: 2396 NNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQ 2455
            N   + Y+YD + +L T+ VN    +  Q R  Y+ N G +  +S  +  R T  R  ++
Sbjct: 2145 NITRYFYEYDADGQLQTVSVN----DKTQWRYSYDLN-GDINLLSHGKSARLTPLRYDLR 2199

Query: 2456 DTSKQFFTIT-DYDDHGRIKT-----FLINI-----KAFDV---FRLELEYDARNRIKTK 2501
            D   +   I    D+ G ++      F  N      KA++    + ++  YD   R    
Sbjct: 2200 DRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVAS 2259

Query: 2502 KLMIGD-TAFSERISYN--YDGHLMEVVGSEDDLKYNYDENGNVIGI-IEHGEKRYLGYD 2557
            K  +G    F    + N     HL     SE    Y YD  G++I + +  GE+ Y+  D
Sbjct: 2260 KSSLGQHLQFFVDATANPIRVTHLYNHTSSEITSLY-YDLQGHLIAMELSSGEEYYVACD 2318

Query: 2558 IGDRVVQYGDVEFSSYDGRGFVGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNT 2617
                 +      FSS       G ++KEI  +P+G I  D+ P F V + FHGG++D+ T
Sbjct: 2319 NTGTPLAV----FSSR------GQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLT 2368

Query: 2618 NLIYLENRLYDPVVGQWMTPSWEHLATKLSL-PTDIFIYRFKNNDPINKQQNVP-YMTSL 2675
             L++L  R YD V G+W T ++ H+  +L+L P    +Y F+NN P+ K Q+V  Y T +
Sbjct: 2369 KLVHLGQRDYDVVAGRWTT-AYHHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDI 2427

Query: 2676 NSWLQLYGYDLNKMMGS----KYIN-DMIFQPMTSVTAAQLAPDFGVMSGLQCIIEKVND 2730
             SWL+L+G+ L+ ++      +  N ++ ++ +   T  Q       + G+QC ++K   
Sbjct: 2428 RSWLELFGFQLHNVLPGFPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLR 2487

Query: 2731 KLSDIEFVP-TPLLKM-EPITRNLLPRVSYKRGVFGEGVLISRVDGRAFISVADGANSVV 2788
                ++ +P TP       +     PR +    VFG+G+  +  DG     +   AN   
Sbjct: 2488 NFISLDQLPMTPRYNDGRCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDS 2547

Query: 2789 EDVITTVFNNSYFLD-VHFSIHDQDVFYFVKDNSLKIRDDMEELRRLSGK--------FN 2839
               +  + NN+++L+ +HF+I  +D  YF+K  SL+  +D+  +    G+          
Sbjct: 2548 RR-LAAILNNAHYLENLHFTIEGRDTHYFIKLGSLE--EDLVLIGNTGGRRILENGVNVT 2604

Query: 2840 VSQDETNDQGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAWEREKA 2899
            VSQ  +   G   R   +          +RYG    +E+  +L+ A +RA  +AW +E+ 
Sbjct: 2605 VSQMTSLLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQR 2664

Query: 2900 LVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
             +  G EG  +WTE EK++L+S G V G+    V S+ +Y +L+D   NI F+
Sbjct: 2665 RLQEGEEGIRAWTEGEKQQLLSTGRVQGYDGYFVLSVEQYLELSDSANNIHFM 2717


>AB032953-1|BAA86441.2| 2144|Homo sapiens KIAA1127 protein protein.
          Length = 2144

 Score = 1115 bits (2761), Expect = 0.0
 Identities = 599/1674 (35%), Positives = 929/1674 (55%), Gaps = 72/1674 (4%)

Query: 934  ECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCK 993
            EC +  ++C  P C GHG C++G C C  GYKG+ C E+DC  PTCS HG C+ G C+C 
Sbjct: 2    ECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCS 61

Query: 994  KGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGR 1053
             GW G +C   +   +QC   CSGHGT+  DT  CSC   W G DCS EVCS++CG HG 
Sbjct: 62   PGWGGLNC---ELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGV 118

Query: 1054 CVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL---------E 1104
            C+G +C C  GW+G  C  R+C  RC EHG CK+G C C  GWNG HCT+         +
Sbjct: 119  CIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIGRQTAGTETD 178

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
            GCP  C G+G+C +  +  W+C C  GW GP C    E  C D++DN+ DGLVDC DP+C
Sbjct: 179  GCPDLCNGNGRCTLGQNS-WQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDC 237

Query: 1165 CQSPACKSSQLCVSSPKPTDILLRKQP--PAITASFFERMKFLIDEGSLQNYAKQETFNE 1222
            C   AC++S LC  S  P DI+ + Q   PA+  SF++R+K L  + S      +  FN 
Sbjct: 238  CLQSACQNSLLCRGSRDPLDIIQQGQTDWPAV-KSFYDRIKLLAGKDSTHIIPGENPFNS 296

Query: 1223 SRSAVIRGRVITTLGSGLVGVRVS-TSTPLEGFTLTREDGWFDLLVNGGGAVTLHFGRSP 1281
            S  ++IRG+V+TT G+ LVGV VS    P  G+T+TR+DG FDL+ NGG ++TLHF R+P
Sbjct: 297  SLVSLIRGQVVTTDGTPLVGVNVSFVKYPKYGYTITRQDGTFDLIANGGASLTLHFERAP 356

Query: 1282 FKRSTQVVFVPWNXXXXXXXXXMTTADEKTGMGPPQACLAHDYDMMKPVVLATWKHGFQG 1341
            F    + V++PWN         M T   KT      +C    +    P+++++    F  
Sbjct: 357  FMSQERTVWLPWN-----SFYAMDTLVMKTEENSIPSCDLSGFVRPDPIIISSPLSTFFS 411

Query: 1342 ACPDKSAILAESQVVQESLQIPGTGLNLVYHSSRAAGYLSTIQLQLTPEIVPPTLALIHL 1401
            A P ++ I+ E+QV+ E +++PG+ + L Y SSR AGY S +++ +T   VP  L  +HL
Sbjct: 412  AAPGQNPIVPETQVLHEEIELPGSNVKLRYLSSRTAGYKSLLKITMTQSTVPLNLIRVHL 471

Query: 1402 RITIEGILFEKTFEADPIIKFTYSWNRLNVYRQRVYGVTTALVKVGYQYTDCKD-IIWNV 1460
             + +EG LF+K+F+A P + +T+ W++ + Y QRVYG++ A+V VG++Y  C   I+W  
Sbjct: 472  MVAVEGHLFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAVVSVGFEYETCPSLILWEK 531

Query: 1461 QTTKLSGHDMSISDVGGWNLDIHHRYNFHEGILQKGDGTNIYLKHKPRLIITTMGDGRQR 1520
            +T  L G ++  S++GGW+LD HH  N   GIL KG G N +L  +P +I + MG+GR+R
Sbjct: 532  RTALLQGFELDPSNLGGWSLDKHHILNVKSGILHKGTGENQFLTQQPAIITSIMGNGRRR 591

Query: 1521 KLECGSECIGPATKQRXXXXXXXXXXXDGSIFVGDFNLVRKINTDGTVRTLVKL------ 1574
             + C S C G A   +           DGS++VGDFN +R+I     V ++++L      
Sbjct: 592  SISCPS-CNGLAEGNKLLAPVALAVGIDGSLYVGDFNYIRRIFPSRNVTSILELRNKEFK 650

Query: 1575 NATRVSYRYHMALSPLDGTLYISDPESHQIIKVHNTEDFSDPEHNWETVVGSGERCLPGD 1634
            ++   +++Y++A+ P+ G+LY+SD  S +I +V +     D   N E V G+GE+CLP D
Sbjct: 651  HSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYRVKSLSGTKDLAGNSEVVAGTGEQCLPFD 710

Query: 1635 EAHCGDGALARDAKLAYPKGVAVSVDNVVYFADGTNIRMVDRDGIITTVIGNHMHRAHWK 1694
            EA CGDG  A DA L  P+G+AV  + ++YF D T IR VD++GII+T++G++   A  +
Sbjct: 711  EARCGDGGKAIDATLMSPRGIAVDKNGLMYFVDATMIRKVDQNGIISTLLGSNDLTA-VR 769

Query: 1695 PIPCEGTLSVEEVHLRWPTELAINPLDNSLHIIDDHMILQMAPDGRVKVIAGRPLHCPAP 1754
            P+ C+ ++ V +V L WPT+LA+NP+DNSL+++++++IL++  + +V +IAGRP+HC  P
Sbjct: 770  PLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVLENNVILRITENHQVSIIAGRPMHCQVP 829

Query: 1755 VSGYDM-ELATYATLVMPQSIAFGAAGDLYVAESDSQRINRVRLITTDGKISLYAGAESK 1813
               Y + +LA ++ L    +IA    G LY+ E+D ++INR+R +TT+G+I L AGA S 
Sbjct: 830  GIDYSLSKLAIHSALESASAIAISHTGVLYITETDEKKINRLRQVTTNGEICLLAGAASD 889

Query: 1814 CNCL-ERGCDCFEADHFLASNSKFNTISAVVVSPDGIVHIADQANYRIRSVMASIPDASG 1872
            C+C  +  C+C+  D   A+++  N+ S++ V+PDG ++IAD  N RIR+V  + P  + 
Sbjct: 890  CDCKNDVNCNCYSGDDAYATDAILNSPSSLAVAPDGTIYIADLGNIRIRAVSKNKPVLNA 949

Query: 1873 TREYEIYSPDTQEIYIFNRFGQHVMTKNILTGEDNYVFTYTVNTRNGKLSTVTDAAGNKV 1932
              +YE  SP  QE+Y+FN  G H  T +++TGE  Y++ +T +T N  ++ + D  GN +
Sbjct: 950  FNQYEAASPGEQELYVFNADGIHQYTVSLVTGE--YLYNFTYSTDN-DVTELIDNNGNSL 1006

Query: 1933 FLLRDYSSLVNSIENTKGQKCRLKMSRMKMLQELRTPDNFNVTFDYHRTTGLLKSKYDST 1992
             + RD S +   +     Q   L +     L+ + T +       Y   TGLL +K D T
Sbjct: 1007 KIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKVVSTQNLELGLMTYDGNTGLLATKSDET 1066

Query: 1993 GRSYIYNYDECGRLTSAVTPTGRIINLTFDLGLKGAIVRVSENNR-KPVSILIKGSSVN- 2050
            G +  Y+YD  GRLT+   PTG + +L  ++  K   + +  +NR   V+++   SSV  
Sbjct: 1067 GWTTFYDYDHEGRLTNVTRPTGVVTSLHREME-KSITIDIENSNRDDDVTVITNLSSVEA 1125

Query: 2051 --TKIGEAEKKXXXXXXXXXXXXM-PWGHVISTDTVPYTILAEIDPILGE-SYPVPAKQG 2106
              T + +  +             M   G  IS  + P+ +   I P +G  +  +P + G
Sbjct: 1126 SYTVVQDQVRNSYQLCNNGTLRVMYANGMGISFHSEPHVLAGTITPTIGRCNISLPMENG 1185

Query: 2107 TEVGGDLANRFEWRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVAVF 2166
                    N  EWR    R    KGK    V   GRKLRV+G NLL+++YDR+  T  ++
Sbjct: 1186 -------LNSIEWRL---RKEQIKGK----VTIFGRKLRVHGRNLLSIDYDRNIRTEKIY 1231

Query: 2167 MDDKYELLNVTYDRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRAGR 2226
             D +   L + YD+  RP  W P SG+ + V + Y    RL     G ++E    D+ GR
Sbjct: 1232 DDHRKFTLRIIYDQVGRPFLWLPSSGL-AAVNVSYFFNGRLAGLQRGAMSERTDIDKQGR 1290

Query: 2227 LHEIRYGDGSSLAYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTFAL 2286
            +    + DG   +YS+ D   S+ L + + R   Y+ +YD S  L  +T P    H+ + 
Sbjct: 1291 IVSRMFADGKVWSYSYLD--KSMVLLLQSQR--QYIFEYDSSDRLLAVTMPSVARHSMST 1346

Query: 2287 MTSLGYFKYQYFSPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAGAS 2346
             TS+GY +  Y  P +       Y+DDG IL   F     ++ Y Y    KL  ++  ++
Sbjct: 1347 HTSIGYIRNIYNPPESNASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEIVYDST 1406

Query: 2347 AIRYVYHDNTHLVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQY-D 2405
            A+ + Y + T ++K V +    +     Y+   G L D ++   S+ G+ NA F Y Y D
Sbjct: 1407 AVTFGYDETTGVLKMVNLQSGGFSCTIRYR-KIGPLVDKQIYRFSEEGMVNARFDYTYHD 1465

Query: 2406 GNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTIT 2465
             + R+++I   I+   +P    +Y++  G +E      +     N+ +   T+       
Sbjct: 1466 NSFRIASIKPVISETPLPVDLYRYDEISGKVEHFGKFGVIYYDINQII---TTAVMTLSK 1522

Query: 2466 DYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHLM 2523
             +D HGRIK     +    ++ + ++YD+  R+  ++L +G  A + + +Y+Y  DG L 
Sbjct: 1523 HFDTHGRIKEVQYEMFRSLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQ 1582

Query: 2524 EV-VGSEDDLKYNYDENGNVIGIIEHGEKRY--LGYDIGDRVVQYGDVEFSSYD 2574
             V V      +Y+YD NGN+  +      R   L YD+ DR+ + GDV++   D
Sbjct: 1583 SVAVNDRPTWRYSYDLNGNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYKIDD 1636



 Score =  170 bits (414), Expect = 6e-41
 Identities = 159/633 (25%), Positives = 283/633 (44%), Gaps = 56/633 (8%)

Query: 2357 HLVKNVEISDPDYDLKQDYKYHAGILKDAK---MKFNSKSG--LNNAHFKYQYDGNARLS 2411
            H   +  I +  Y++ +   Y   +  D+    +K   K G   N   + Y YDG+ +L 
Sbjct: 1523 HFDTHGRIKEVQYEMFRSLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQLQ 1582

Query: 2412 TIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTIT-DYDDH 2470
            ++ VN    + P  R  Y+ N G+L  ++     R    R  ++D   +   +    DD 
Sbjct: 1583 SVAVN----DRPTWRYSYDLN-GNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYKIDDD 1637

Query: 2471 GRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNYDG---HLMEVVG 2527
            G    +L   +  D+F    EY+++  + T+     + A    + Y YDG          
Sbjct: 1638 G----YLCQ-RGSDIF----EYNSKGLL-TRAY---NKASGWSVQYRYDGVGRRASYKTN 1684

Query: 2528 SEDDLKYNYDENGN---VIGIIEHGEKRY--LGYDIGDRVVQY----GDVEFSSYDGRG- 2577
                L+Y Y +  N   +  +  H       L YD+   +       G+  + + D  G 
Sbjct: 1685 LGHHLQYFYSDLHNPTRITHVYNHSNSEITSLYYDLQGHLFAMESSSGEEYYVASDNTGT 1744

Query: 2578 ------FVGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNTNLIYLENRLYDPVV 2631
                    G ++K+++ + +G+I  DSNP F + + FHGG++D  T L++   R YD + 
Sbjct: 1745 PLAVFSINGPMIKQLQYTAYGEIYYDSNPDFQMVIGFHGGLYDPLTKLVHFTQRDYDVLA 1804

Query: 2632 GQWMTPSWEHLATKLSLPTDIFIYRFKNNDPINKQQNVP-YMTSLNSWLQLYGYDLNKMM 2690
            G+W +P +         P    +Y FK+N+P++ + ++  Y+T + SWL ++G+ L+ ++
Sbjct: 1805 GRWTSPDYTMWKNVGKEPAPFNLYMFKSNNPLSSELDLKNYVTDVKSWLVMFGFQLSNII 1864

Query: 2691 GSKYINDMIF-QPMTSVTAAQLAPDFGVMSGLQCIIEKVNDKLSDIEFVPTPLLKMEPIT 2749
                   M F  P   ++ +Q + +  +++G+Q   E+ N     +E           I 
Sbjct: 1865 PGFPRAKMYFVPPPYELSESQASENGQLITGVQQTTERHNQAFMALEGQVITKKLHASIR 1924

Query: 2750 RNLLPRVSYKRGVFGEGVLISRVDGRAFISVADGANSVVEDVITTVFNNSYFLD-VHFSI 2808
                   +    + G+G++ +  +GR    V+  A+     V  +V NN+Y+LD +H+SI
Sbjct: 1925 EKAGHWFATTTPIIGKGIMFAIKEGRVTTGVSSIASEDSRKV-ASVLNNAYYLDKMHYSI 1983

Query: 2809 HDQDVFYFVK----DNSLKIRDDMEELRRLSGKFN--VSQDETNDQGLEVRVHAVGKGSA 2862
              +D  YFVK    D  L         + L    N  VSQ      G   R   +    +
Sbjct: 1984 EGKDTHYFVKIGSADGDLVTLGTTIGRKVLESGVNVTVSQPTLLVNGRTRRFTNIEFQYS 2043

Query: 2863 QAVIVLRYGVDP---AQERIKLLKHAHKRAATRAWEREKALVAAGWEGRGSWTEEEKEEL 2919
              ++ +RYG+ P    +E+ ++L  A +RA   AW +E+     G EG   WTE EK++L
Sbjct: 2044 TLLLSIRYGLTPDTLDEEKARVLDQARQRALGTAWAKEQQKARDGREGSRLWTEGEKQQL 2103

Query: 2920 ISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
            +S G V G+    V  + +YP+LAD  +NI F+
Sbjct: 2104 LSTGRVQGYEGYYVLPVEQYPELADSSSNIQFL 2136



 Score =  146 bits (353), Expect = 1e-33
 Identities = 79/218 (36%), Positives = 106/218 (48%), Gaps = 28/218 (12%)

Query: 882  CSGKGECLMGHCQCQPGFGGDDCSKSVC-PVLCSQRGEYINGECQCNPGWKGKECSLRHD 940
            C G G C+ G+C C  G+ G+ C +  C    CS  G  +NGEC C+PGW G  C L   
Sbjct: 15   CGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARV 74

Query: 941  ECEVPD-CNGHGHCV--NGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            +C  PD C+GHG  +   G CSC   + G  C  ++     C  HG CI G C C++GW 
Sbjct: 75   QC--PDQCSGHGTYLPDTGLCSCDPNWMGPDC-SVEVCSVDCGTHGVCIGGACRCEEGWT 131

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS---------KEVCSLEC 1048
            GA C     D   C P C  HGT       C C   W+GE C+          + C   C
Sbjct: 132  GAAC-----DQRVCHPRCIEHGT--CKDGKCECREGWNGEHCTIGRQTAGTETDGCPDLC 184

Query: 1049 GPHGRC-VGES---CSCAAGWSGEFCSVRLCDARCAEH 1082
              +GRC +G++   C C  GW G  C+V + +  CA++
Sbjct: 185  NGNGRCTLGQNSWQCVCQTGWRGPGCNVAM-ETSCADN 221



 Score =  111 bits (267), Expect = 4e-23
 Identities = 64/167 (38%), Positives = 77/167 (46%), Gaps = 20/167 (11%)

Query: 878  CPNGCSGKGECL--MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            CP+ CSG G  L   G C C P + G DCS  VC V C   G  I G C+C  GW G  C
Sbjct: 76   CPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAAC 135

Query: 936  SLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFC--------GEID-CPHPTCSGHGFCI 986
              R   C  P C  HG C +GKC C  G+ G+ C         E D CP   C+G+G C 
Sbjct: 136  DQR--VCH-PRCIEHGTCKDGKCECREGWNGEHCTIGRQTAGTETDGCP-DLCNGNGRCT 191

Query: 987  EG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTC 1028
             G     CVC+ GW+G  C    + +     D  G G  D +D   C
Sbjct: 192  LGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCC 238



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 4/35 (11%)

Query: 875 THNCPNGCSGKGECLMG----HCQCQPGFGGDDCS 905
           T  CP+ C+G G C +G     C CQ G+ G  C+
Sbjct: 177 TDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCN 211


>AB037723-1|BAA92540.3| 2016|Homo sapiens KIAA1302 protein protein.
          Length = 2016

 Score =  924 bits (2286), Expect = 0.0
 Identities = 507/1543 (32%), Positives = 827/1543 (53%), Gaps = 69/1543 (4%)

Query: 1070 CSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL---------EGCPRSCAGHGQCRVDN 1120
            C  R C  RCAEHG C++G C C  GWNG HCT+         EGCP  C G+G+C +D 
Sbjct: 2    CDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDL 61

Query: 1121 DGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSP 1180
            +G W C C  GW G  C T  E  C DS+DND DGLVDC DP+CC  P C  + LC+ SP
Sbjct: 62   NG-WHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSP 120

Query: 1181 KPTDILLRKQPPAITA---SFFERMKFLIDEGSLQNYAKQETFNESRSAVIRGRVITTLG 1237
             P DI+   Q P       SF++R+KFL+   S      +  F+   + VIRG+V+T+ G
Sbjct: 121  NPLDIIQETQVPVSQQNLHSFYDRIKFLVGRDSTHIIPGENPFDGGHACVIRGQVMTSDG 180

Query: 1238 SGLVGVRVS-TSTPLEGFTLTREDGWFDLLVNGGGAVTLHFGRSPFKRSTQVVFVPWNXX 1296
            + LVGV +S  + PL G+T++R+DG FDL+ NGG ++ L F R+PF      +++PW+  
Sbjct: 181  TPLVGVNISFVNNPLFGYTISRQDGSFDLVTNGGISIILRFERAPFITQEHTLWLPWDRF 240

Query: 1297 XXXXXXXMTTADEKTGMGPPQACLAHDYDMMKPVVLATWKHGFQGACPDKSAILAESQVV 1356
                   M   + +       +C   ++    PVV  +    F  +C +K  I+ E Q +
Sbjct: 241  FVMETIIMRHEENEI-----PSCDLSNFARPNPVVSPSPLTSFASSCAEKGPIVPEIQAL 295

Query: 1357 QESLQIPGTGLNLVYHSSRAAGYLSTIQLQLTPEIVPPTLALIHLRITIEGILFEKTFEA 1416
            QE + I G  + L Y SSR  GY S +++ LT   +P  L  +HL + +EG LF K F A
Sbjct: 296  QEEISISGCKMRLSYLSSRTPGYKSVLRISLTHPTIPFNLMKVHLMVAVEGRLFRKWFAA 355

Query: 1417 DPIIKFTYSWNRLNVYRQRVYGVTTALVKVGYQYTDCKD-IIWNVQTTKLSGHDMSISDV 1475
             P + + + W++ +VY Q+V+G++ A V VGY+Y  C D I+W  +TT L G+++  S +
Sbjct: 356  APDLSYYFIWDKTDVYNQKVFGLSEAFVSVGYEYESCPDLILWEKRTTVLQGYEIDASKL 415

Query: 1476 GGWNLDIHHRYNFHEGILQKGDGTNIYLKHKPRLIITTMGDGRQRKLECGSECIGPATKQ 1535
            GGW+LD HH  N   GIL KG+G N ++  +P +I + MG+GR+R + C S C G A   
Sbjct: 416  GGWSLDKHHALNIQSGILHKGNGENQFVSQQPPVIGSIMGNGRRRSISCPS-CNGLADGN 474

Query: 1536 RXXXXXXXXXXXDGSIFVGDFNLVRKINTDGTVRTLVKL------NATRVSYRYHMALSP 1589
            +           DGS++VGDFN +R+I   G V  +++L      ++   +++Y++A  P
Sbjct: 475  KLLAPVALTCGSDGSLYVGDFNYIRRIFPSGNVTNILELRNKDFRHSHSPAHKYYLATDP 534

Query: 1590 LDGTLYISDPESHQIIKVHNTEDFSDPEHNWETVVGSGERCLPGDEAHCGDGALARDAKL 1649
            + G +++SD  S ++ K+ +T    D   N E V G+G++CLP D+  CGDG  A +A L
Sbjct: 535  MSGAVFLSDSNSRRVFKIKSTVVVKDLVKNSEVVAGTGDQCLPFDDTRCGDGGKATEATL 594

Query: 1650 AYPKGVAVSVDNVVYFADGTNIRMVDRDGIITTVIGNHMHRAHWKPIPCEGTLSVEEVHL 1709
              P+G+ V    ++YF DGT IR +D++GII+T++G++      +P+ C+  + + +VHL
Sbjct: 595  TNPRGITVDKFGLIYFVDGTMIRRIDQNGIISTLLGSN-DLTSARPLSCDSVMDISQVHL 653

Query: 1710 RWPTELAINPLDNSLHIIDDHMILQMAPDGRVKVIAGRPLHCPAPVSGYDM--ELATYAT 1767
             WPT+LAINP+DNSL+++D++++LQ++ + +V+++AGRP+HC  P   + +  ++A +AT
Sbjct: 654  EWPTDLAINPMDNSLYVLDNNVVLQISENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHAT 713

Query: 1768 LVMPQSIAFGAAGDLYVAESDSQRINRVRLITTDGKISLYAGAESKCNCL-ERGCDCFEA 1826
            L    ++A    G LY+AE+D ++INR+R +TT G+ISL AGA S C+C  +  CDCF  
Sbjct: 714  LESATALAVSHNGVLYIAETDEKKINRIRQVTTSGEISLVAGAPSGCDCKNDANCDCFSG 773

Query: 1827 DHFLASNSKFNTISAVVVSPDGIVHIADQANYRIRSVMASIPDASGTREYEIYSPDTQEI 1886
            D   A ++K NT S++ V  DG +++AD  N RIR +  + P  +    YE+ SP  QE+
Sbjct: 774  DDGYAKDAKLNTPSSLAVCADGELYVADLGNIRIRFIRKNKPFLNTQNMYELSSPIDQEL 833

Query: 1887 YIFNRFGQHVMTKNILTGEDNYVFTYTVNTRNGKLSTVTDAAGNKVFLLRDYSSLVNSIE 1946
            Y+F+  G+H+ T+++ TG+  Y FTY   T +G ++ +TD  GN V + RD + +   + 
Sbjct: 834  YLFDTTGKHLYTQSLPTGDYLYNFTY---TGDGDITLITDNNGNMVNVRRDSTGMPLWLV 890

Query: 1947 NTKGQKCRLKMSRMKMLQELRTPDNFNVTFDYHRTTGLLKSKYDSTGRSYIYNYDECGRL 2006
               GQ   + M     L+ + T  +      YH  +GLL +K +  G +  Y YD  GRL
Sbjct: 891  VPDGQVYWVTMGTNSALKSVTTQGHELAMMTYHGNSGLLATKSNENGWTTFYEYDSFGRL 950

Query: 2007 TSAVTPTGRIINLTFDLGLKGAIVRVSENNRKPVSIL----IKGSSVNTKIGEAEKKXXX 2062
            T+   PTG++ +   D       V+V  +++  V+I       G+       +       
Sbjct: 951  TNVTFPTGQVSSFRSDTD-SSVHVQVETSSKDDVTITTNLSASGAFYTLLQDQVRNSYYI 1009

Query: 2063 XXXXXXXXXMPWGHVISTDTVPYTILAEIDPILGE-SYPVPAKQGTEVGGDLANRFEWRY 2121
                     +  G  ++  T P+ +   ++P +G+ +  +P   G        N  EWR 
Sbjct: 1010 GADGSLRLLLANGMEVALQTEPHLLAGTVNPTVGKRNVTLPIDNG-------LNLVEWR- 1061

Query: 2122 FLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVAVFMDDKYELLNVTYDRT 2181
              +R   ++G+    V   GR+LRV+  NLL+L++DR T T  ++ D +   L + YD+ 
Sbjct: 1062 --QRKEQARGQ----VTVFGRRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFTLRILYDQA 1115

Query: 2182 ARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRAGRLHEIRYGDGSSLAYS 2241
             RP  W P S + + V + Y     +     G ++E   +D+AGR+    + DG + +Y+
Sbjct: 1116 GRPSLWSPSSRL-NGVNVTYSPGGYIAGIQRGIMSERMEYDQAGRITSRIFADGKTWSYT 1174

Query: 2242 FRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTFALMTSLGYFKYQYFSPM 2301
            + +   S+ L + + R   Y+ ++D +  L ++T P     T   + S+GY++  Y  P 
Sbjct: 1175 YLE--KSMVLLLHSQR--QYIFEFDKNDRLSSVTMPNVARQTLETIRSVGYYRNIYQPPE 1230

Query: 2302 NRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAGASAIRYVYHDNTHLVKN 2361
                    + +DGH+L   +     +++Y Y    KL   L   + + + Y +   ++K 
Sbjct: 1231 GNASVIQDFTEDGHLLHTFYLGTGRRVIYKYGKLSKLAETLYDTTKVSFTYDETAGMLKT 1290

Query: 2362 VEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQYDGNARLSTIDVNINSKE 2421
            + + +  +     Y+   G L D ++   ++ G+ NA F Y YD + R++++   IN   
Sbjct: 1291 INLQNEGFTCTIRYR-QIGPLIDRQIFRFTEEGMVNARFDYNYDNSFRVTSMQAVINETP 1349

Query: 2422 MPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTITDYDDHGRIKTFLINIK 2481
            +P    +Y+   G  E      +     N+ +   T+        +D +GR+K     I 
Sbjct: 1350 LPIDLYRYDDVSGKTEQFGKFGVIYYDINQII---TTAVMTHTKHFDAYGRMKEVQYEIF 1406

Query: 2482 AFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHLMEVVGSEDDL-KYNYDE 2538
               ++ + ++YD   R+  K+L +G  A + R SY Y  DG L  V  ++  L +Y+YD 
Sbjct: 1407 RSLMYWMTVQYDNMGRVVKKELKVGPYANTTRYSYEYDADGQLQTVSINDKPLWRYSYDL 1466

Query: 2539 NGNVIGIIEHGEKRY--LGYDIGDRVVQYGDVEFSSYDGRGFV 2579
            NGN+  +      R   L YDI DR+ + GDV++   D  GF+
Sbjct: 1467 NGNLHLLSPGNSARLTPLRYDIRDRITRLGDVQY-KMDEDGFL 1508



 Score =  177 bits (430), Expect = 7e-43
 Identities = 158/598 (26%), Positives = 280/598 (46%), Gaps = 65/598 (10%)

Query: 2396 NNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQ 2455
            N   + Y+YD + +L T+ +N    + P  R  Y+ N G+L  +S     R T  R  ++
Sbjct: 1435 NTTRYSYEYDADGQLQTVSIN----DKPLWRYSYDLN-GNLHLLSPGNSARLTPLRYDIR 1489

Query: 2456 DTSKQFFTIT-DYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERI 2514
            D   +   +    D+ G ++      +  D+F    EY++   +    +   + A S  +
Sbjct: 1490 DRITRLGDVQYKMDEDGFLRQ-----RGGDIF----EYNSAGLL----IKAYNRAGSWSV 1536

Query: 2515 SYNYDGHLMEVVGSEDD----LKYNYDENGN---VIGIIEHGEKRY--LGYDIGDRV--- 2562
             Y YDG L   V S+      L++ Y +  N   V  +  H       L YD+   +   
Sbjct: 1537 RYRYDG-LGRRVSSKSSHSHHLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAM 1595

Query: 2563 -VQYGDVEFSSYDGRGF-------VGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFD 2614
             +  GD  + + D  G         G ++K+I  + +G+I  D+NP+F + + +HGG++D
Sbjct: 1596 ELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDTNPNFQIIIGYHGGLYD 1655

Query: 2615 YNTNLIYLENRLYDPVVGQWMTPS---WEHLATKLSLPTDIFIYRFKNNDPINKQQNVP- 2670
              T L+++  R YD + G+W +P    W+HL++   +P +  +Y FKNN+PI+  Q++  
Sbjct: 1656 PLTKLVHMGRRDYDVLAGRWTSPDHELWKHLSSSNVMPFN--LYMFKNNNPISNSQDIKC 1713

Query: 2671 YMTSLNSWLQLYGYDLNKMMGSKYINDM-IFQPMTSVTAAQLA----PDFGVMSGLQCII 2725
            +MT +NSWL  +G+ L+ ++      DM   +P   +   Q+      +   + G+QC +
Sbjct: 1714 FMTDVNSWLLTFGFQLHNVIPGYPKPDMDAMEPSYELIHTQMKTQEWDNSKSILGVQCEV 1773

Query: 2726 EKVNDKLSDIE----FVPTPLLKMEPITRNLLPRVSYKRGVFGEGVLISRVDGRAFISVA 2781
            +K       +E       + +   +   +    + +    VFG+GV  +  DGR    + 
Sbjct: 1774 QKQLKAFVTLERFDQLYGSTITSCQQAPKT--KKFASSGSVFGKGVKFALKDGRVTTDII 1831

Query: 2782 DGANSVVEDVITTVFNNSYFLD-VHFSIHDQDVFYFVK----DNSLKIRDDMEELRRLSG 2836
              AN     V   + N++++L+ +HF+I   D  YFVK    +  L I       R L  
Sbjct: 1832 SVANEDGRRV-AAILNHAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLSGGRRTLEN 1890

Query: 2837 KFNVSQDETND--QGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAW 2894
              NV+  + N    G   R   +        +  RYG    +E+ ++L+ A +RA  +AW
Sbjct: 1891 GVNVTVSQINTVLNGRTRRYTDIQLQYGALCLNTRYGTTLDEEKARVLELARQRAVRQAW 1950

Query: 2895 EREKALVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
             RE+  +  G EG  +WTE EK++++S G V G+    V S+ +YP+L+D   NI F+
Sbjct: 1951 AREQQRLREGEEGLRAWTEGEKQQVLSTGRVQGYDGFFVISVEQYPELSDSANNIHFM 2008



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 8/87 (9%)

Query: 969  CGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGT---MDKDALQCLPD-CSGHG--TFD 1022
            C +  C HP C+ HG C +G C C  GW G  C     +D+   +  P  C+G+G  T D
Sbjct: 2    CDQRAC-HPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLD 60

Query: 1023 VDTQTCSCHAKWSGEDCSKEVCSLECG 1049
            ++   C C   W G  C   +    CG
Sbjct: 61   LNGWHCVCQLGWRGAGCDTSM-ETACG 86



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 10/76 (13%)

Query: 904 CSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPD------CNGHGHC---V 954
           C +  C   C++ G   +G+C+C+PGW G+ C++ H    V        CNG+G C   +
Sbjct: 2   CDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDL 61

Query: 955 NG-KCSCVRGYKGKFC 969
           NG  C C  G++G  C
Sbjct: 62  NGWHCVCQLGWRGAGC 77



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 35/98 (35%), Positives = 46/98 (46%), Gaps = 15/98 (15%)

Query: 945  PDCNGHGHCVNGKCSCVRGYKGKFCG---------EIDCPHPTCSGHGFC---IEGT-CV 991
            P C  HG C +GKC C  G+ G+ C          +  CP   C+G+G C   + G  CV
Sbjct: 9    PRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPG-LCNGNGRCTLDLNGWHCV 67

Query: 992  CKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTC 1028
            C+ GW+GA C T  + A     D  G G  D +D   C
Sbjct: 68   CQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCC 105



 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 17/98 (17%)

Query: 878 CPNGCSGKGECLMGHCQCQPGFGGDDCS---------KSVCPVLCSQRGEY---ING-EC 924
           C   C+  G C  G C+C PG+ G+ C+         K  CP LC+  G     +NG  C
Sbjct: 7   CHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHC 66

Query: 925 QCNPGWKGKECSLRHDEC--EVPDCNGHG--HCVNGKC 958
            C  GW+G  C    +    +  D +G G   C++  C
Sbjct: 67  VCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDC 104


>BX640737-1|CAE45850.1| 1399|Homo sapiens hypothetical protein
            protein.
          Length = 1399

 Score =  433 bits (1066), Expect = e-120
 Identities = 267/919 (29%), Positives = 472/919 (51%), Gaps = 42/919 (4%)

Query: 1674 VDRDGIITTVIGNHMHRAHWKPIPCEGTLSVEEVHLRWPTELAINPLDNSLHIIDDHMIL 1733
            +D++GII+T++G++      +P+ C+  + + +VHL WPT+LAINP+DNSL+++D++++L
Sbjct: 2    IDQNGIISTLLGSN-DLTSARPLSCDSVMDISQVHLEWPTDLAINPMDNSLYVLDNNVVL 60

Query: 1734 QMAPDGRVKVIAGRPLHCPAPVSGYDM--ELATYATLVMPQSIAFGAAGDLYVAESDSQR 1791
            Q++ + +V+++AGRP+HC  P   + +  ++A +ATL    ++A    G LY+AE+D ++
Sbjct: 61   QISENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHATLESAIALAVSHNGVLYIAETDEKK 120

Query: 1792 INRVRLITTDGKISLYAGAESKCNCL-ERGCDCFEADHFLASNSKFNTISAVVVSPDGIV 1850
            INR+R +TT G+ISL AGA S C+C  +  CDCF  D   A ++K NT S++ V  DG +
Sbjct: 121  INRIRQVTTSGEISLVAGAPSGCDCKNDANCDCFSGDDGYAKDAKLNTPSSLAVCADGEL 180

Query: 1851 HIADQANYRIRSVMASIPDASGTREYEIYSPDTQEIYIFNRFGQHVMTKNILTGEDNYVF 1910
            ++AD  N RIR +  + P  +    YE+ SP  QE+Y+F+  G+H+ T+++ TG+  Y F
Sbjct: 181  YVADLGNIRIRFIRKNKPFLNTQNMYELSSPIDQELYLFDTTGKHLYTQSLPTGDYLYNF 240

Query: 1911 TYTVNTRNGKLSTVTDAAGNKVFLLRDYSSLVNSIENTKGQKCRLKMSRMKMLQELRTPD 1970
            TY   T +G ++ +TD  GN V + RD + +   +    GQ   + M     L+ + T  
Sbjct: 241  TY---TGDGDITLITDNNGNMVNVRRDSTGMPLWLVVPDGQVYWVTMGTNSALKSVTTQG 297

Query: 1971 NFNVTFDYHRTTGLLKSKYDSTGRSYIYNYDECGRLTSAVTPTGRIINLTFDLGLKGAIV 2030
            +      YH  +GLL +K +  G +  Y YD  GRLT+   PTG++ +   D       V
Sbjct: 298  HELAMMTYHGNSGLLATKSNENGWTTFYEYDSFGRLTNVTFPTGQVSSFRSDTD-SSVHV 356

Query: 2031 RVSENNRKPVSIL----IKGSSVNTKIGEAEKKXXXXXXXXXXXXMPWGHVISTDTVPYT 2086
            +V  +++  V+I       G+       +                +  G  ++  T P+ 
Sbjct: 357  QVETSSKDDVTITTNLSASGAFYTLLQDQVRNSYYIGADGSLRLLLANGMEVALQTEPHL 416

Query: 2087 ILAEIDPILGE-SYPVPAKQGTEVGGDLANRFEWRYFLRRLMSSKGKSSKAVAQIGRKLR 2145
            +   ++P +G+ +  +P   G        N  EWR   +R   ++G+    V   GR+LR
Sbjct: 417  LAGTVNPTVGKRNVTLPIDNG-------LNLVEWR---QRKEQARGQ----VTVFGRRLR 462

Query: 2146 VNGENLLTLEYDRDTSTVAVFMDDKYELLNVTYDRTARPVKWGPRSGIFSEVELEYDRFN 2205
            V+  NLL+L++DR T T  ++ D +   L + YD+  RP  W P S + + V + Y    
Sbjct: 463  VHNRNLLSLDFDRVTRTEKIYDDHRKFTLRILYDQAGRPSLWSPSSRL-NGVNVTYSPGG 521

Query: 2206 RLTRWSWGDLNETYGFDRAGRLHEIRYGDGSSLAYSFRDMFTSLPLKVTTPRGSDYLLDY 2265
             +     G ++E   +D+AGR+    + DG + +Y++ +   S+ L + + R   Y+ ++
Sbjct: 522  YIAGIQRGIMSERMEYDQAGRITSRIFADGKTWSYTYLE--KSMVLLLHSQR--QYIFEF 577

Query: 2266 DDSGALQNLTTPRGHIHTFALMTSLGYFKYQYFSPMNRHPYEIFYNDDGHILSKIFPHQS 2325
            D +  L ++T P     T   + S+GY++  Y  P         + +DGH+L   +    
Sbjct: 578  DKNDRLSSVTMPNVARQTLETIRSVGYYRNIYQPPEGNASVIQDFTEDGHLLHTFYLGTG 637

Query: 2326 GKILYVYDGTGKLETVLAGASAIRYVYHDNTHLVKNVEISDPDYDLKQDYKYHAGILKDA 2385
             +++Y Y    KL   L   + + + Y +   ++K + + +  +     Y+   G L D 
Sbjct: 638  RRVIYKYGKLSKLAETLYDTTKVSFTYDETAGMLKTINLQNEGFTCTIRYR-QIGPLIDR 696

Query: 2386 KMKFNSKSGLNNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIY 2445
            ++   ++ G+ NA F Y YD + R++++   IN   +P    +Y+   G  E      + 
Sbjct: 697  QIFRFTEEGMVNARFDYNYDNSFRVTSMQAVINETPLPIDLYRYDDVSGKTEQFGKFGVI 756

Query: 2446 RNTFNRTVMQDTSKQFFTITDYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMI 2505
                N+ +   T+        +D +GR+K     I    ++ + ++YD   R+  K+L +
Sbjct: 757  YYDINQII---TTAVMTHTKHFDAYGRMKEVQYEIFRSLMYWMTVQYDNMGRVVKKELKV 813

Query: 2506 GDTAFSERISYNY--DGHLMEVVGSEDDL-KYNYDENGNVIGIIEHGEKRY--LGYDIGD 2560
            G  A + R SY Y  DG L  V  ++  L +Y+YD NGN+  +      R   L YDI D
Sbjct: 814  GPYANTTRYSYEYDADGQLQTVSINDKPLWRYSYDLNGNLHLLSPGNSARLTPLRYDIRD 873

Query: 2561 RVVQYGDVEFSSYDGRGFV 2579
            R+ + GDV++   D  GF+
Sbjct: 874  RITRLGDVQY-KMDEDGFL 891



 Score =  175 bits (425), Expect = 3e-42
 Identities = 157/598 (26%), Positives = 280/598 (46%), Gaps = 65/598 (10%)

Query: 2396 NNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQ 2455
            N   + Y+YD + +L T+ +N    + P  R  Y+ N G+L  +S     R T  R  ++
Sbjct: 818  NTTRYSYEYDADGQLQTVSIN----DKPLWRYSYDLN-GNLHLLSPGNSARLTPLRYDIR 872

Query: 2456 DTSKQFFTIT-DYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERI 2514
            D   +   +    D+ G ++      +  D+F    EY++   +    +   + A S  +
Sbjct: 873  DRITRLGDVQYKMDEDGFLRQ-----RGGDIF----EYNSAGLL----IKAYNRAGSWSV 919

Query: 2515 SYNYDGHLMEVVGSEDD----LKYNYDENGN---VIGIIEHGEKRY--LGYDIGDRV--- 2562
             Y YDG L   V S+      L++ Y +  N   V  +  H       L YD+   +   
Sbjct: 920  RYRYDG-LGRRVSSKSSHSHHLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAM 978

Query: 2563 -VQYGDVEFSSYDGRGF-------VGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFD 2614
             +  GD  + + D  G         G ++K+I  + +G+I  D++P+F + + +HGG++D
Sbjct: 979  ELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDTDPNFQIIIGYHGGLYD 1038

Query: 2615 YNTNLIYLENRLYDPVVGQWMTPS---WEHLATKLSLPTDIFIYRFKNNDPINKQQNVP- 2670
              T L+++  R YD + G+W +P    W+HL++   +P +  +Y FKNN+PI+  Q++  
Sbjct: 1039 PLTKLVHMGRRDYDVLAGRWTSPDHELWKHLSSSNVMPFN--LYMFKNNNPISNSQDIKC 1096

Query: 2671 YMTSLNSWLQLYGYDLNKMMGSKYINDM-IFQPMTSVTAAQLA----PDFGVMSGLQCII 2725
            +MT +NSWL  +G+ L+ ++      DM   +P   +   Q+      +   + G+QC +
Sbjct: 1097 FMTDVNSWLLTFGFQLHNVIPGYPKPDMDAMEPSYELIHTQMKTQEWDNSKSILGVQCEV 1156

Query: 2726 EKVNDKLSDIE----FVPTPLLKMEPITRNLLPRVSYKRGVFGEGVLISRVDGRAFISVA 2781
            +K       +E       + +   +   +    + +    VFG+GV  +  DGR    + 
Sbjct: 1157 QKQLKAFVTLERFDQLYGSTITSCQQAPKT--KKFASSGSVFGKGVKFALKDGRVTTDII 1214

Query: 2782 DGANSVVEDVITTVFNNSYFLD-VHFSIHDQDVFYFVK----DNSLKIRDDMEELRRLSG 2836
              AN     V   + N++++L+ +HF+I   D  YFVK    +  L I       R L  
Sbjct: 1215 SVANEDGRRV-AAILNHAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLSGGRRTLEN 1273

Query: 2837 KFNVSQDETND--QGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAW 2894
              NV+  + N    G   R   +        +  RYG    +E+ ++L+ A +RA  +AW
Sbjct: 1274 GVNVTVSQINTVLNGRTRRYTDIQLQYGALCLNTRYGTTLDEEKARVLELARQRAVRQAW 1333

Query: 2895 EREKALVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
             RE+  +  G EG  +WTE EK++++S G V G+    V S+ +YP+L+D   NI F+
Sbjct: 1334 AREQQRLREGEEGLRAWTEGEKQQVLSTGRVQGYDGFFVISVEQYPELSDSANNIHFM 1391



 Score = 41.5 bits (93), Expect = 0.045
 Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 8/87 (9%)

Query: 1591 DGTLYISDPESHQIIKVHNTEDFSDPEHNWETVVGSGERCLPGDEAHC----GDGALARD 1646
            +G LYI++ +  +I ++       +       V G+   C   ++A+C    GD   A+D
Sbjct: 108  NGVLYIAETDEKKINRIRQVTTSGEIS----LVAGAPSGCDCKNDANCDCFSGDDGYAKD 163

Query: 1647 AKLAYPKGVAVSVDNVVYFADGTNIRM 1673
            AKL  P  +AV  D  +Y AD  NIR+
Sbjct: 164  AKLNTPSSLAVCADGELYVADLGNIRI 190



 Score = 39.9 bits (89), Expect = 0.14
 Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 17/162 (10%)

Query: 1649 LAYPKGVAVS-VDNVVYFADGTNIRMVDRDGIITTVIGNHMHRAHWKPIPCEGTLSVEEV 1707
            L +P  +A++ +DN +Y  D   +  +  +  +  V G  MH     P      LS   +
Sbjct: 36   LEWPTDLAINPMDNSLYVLDNNVVLQISENHQVRIVAGRPMHCQ--VPGIDHFLLSKVAI 93

Query: 1708 HLRWPTELAINPLDNSLHIIDD------HMILQMAPDGRVKVIAGRPLHCPAP------- 1754
            H    + +A+    N +  I +      + I Q+   G + ++AG P  C          
Sbjct: 94   HATLESAIALAVSHNGVLYIAETDEKKINRIRQVTTSGEISLVAGAPSGCDCKNDANCDC 153

Query: 1755 VSGYDMELATYATLVMPQSIAFGAAGDLYVAESDSQRINRVR 1796
             SG D   A  A L  P S+A  A G+LYVA+  + RI  +R
Sbjct: 154  FSG-DDGYAKDAKLNTPSSLAVCADGELYVADLGNIRIRFIR 194


>X71923-1|CAA50739.1|  750|Homo sapiens tenascin-X precursor protein.
          Length = 750

 Score =  245 bits (600), Expect = 2e-63
 Identities = 109/263 (41%), Positives = 142/263 (53%), Gaps = 16/263 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C+ +G C  G C C PG+ G DC    CP  C  RG   NG C CN G+ G++C 
Sbjct: 406  SCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCG 465

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C   DC G G C +G+C C  GY G+ CG   CP   C G G C++G CVC  G+
Sbjct: 466  VR--SCP-GDCRGRGRCESGRCMCWPGYTGRDCGTRACPGD-CRGRGRCVDGRCVCNPGF 521

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG+      +C  DC GHG    +   C C A +SGEDCS   C   C   G+C+ 
Sbjct: 522  TGEDCGSR-----RCPGDCRGHGL--CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 574

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SGE C VR C   C++HG C++G C+C  G+    C++  CP +C G G+C
Sbjct: 575  GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 634

Query: 1117 RVDNDGRWECKCFDGWDGPDCTT 1139
                +GR  C C  G+ GP C T
Sbjct: 635  ---EEGR--CLCDPGYTGPTCAT 652



 Score =  238 bits (582), Expect = 3e-61
 Identities = 119/308 (38%), Positives = 154/308 (50%), Gaps = 24/308 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP GCS +G C  G C C PG+ GDDC    CP  CSQRG   NG C CNPG+ G++C 
Sbjct: 251  SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 310

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C +G+C C  GY G+ CG   CP   C   G C++G CVC  G+
Sbjct: 311  VR--SCP-RGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD-CGEGGRCVDGRCVCWPGY 366

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC T       C  DC G G  + D + C C   +SG+DC    C  +C   GRC  
Sbjct: 367  TGEDCSTRT-----CPRDCRGRGRCE-DGE-CICDTGYSGDDCGVRSCPGDCNQRGRCED 419

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C  R C   C   G+C+NG C+C +G++G  C +  CP  C G G+C
Sbjct: 420  GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 479

Query: 1117 RVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                 GR  C C+ G+ G DC T   + C      D  G   C D  C  +P   + + C
Sbjct: 480  ---ESGR--CMCWPGYTGRDCGT---RAC----PGDCRGRGRCVDGRCVCNPGF-TGEDC 526

Query: 1177 VSSPKPTD 1184
             S   P D
Sbjct: 527  GSRRCPGD 534



 Score =  237 bits (581), Expect = 3e-61
 Identities = 108/263 (41%), Positives = 135/263 (51%), Gaps = 16/263 (6%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T +CP  C   G C+ G C C PG+ G+DCS   CP  C  RG   +GEC C+ G+ G +
Sbjct: 342  TRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDD 401

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C +R   C   DCN  G C +G+C C  GY G  CG   CP   C G G C  G CVC  
Sbjct: 402  CGVR--SCP-GDCNQRGRCEDGRCVCWPGYTGTDCGSRACPR-DCRGRGRCENGVCVCNA 457

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCG        C  DC G G    ++  C C   ++G DC    C  +C   GRC
Sbjct: 458  GYSGEDCGVR-----SCPGDCRGRGR--CESGRCMCWPGYTGRDCGTRACPGDCRGRGRC 510

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
            V   C C  G++GE C  R C   C  HG C++G C+C +G++G  C+   CP  C G G
Sbjct: 511  VDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRG 570

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
            QC    DGR  C C DG+ G DC
Sbjct: 571  QCL---DGR--CVCEDGYSGEDC 588



 Score =  237 bits (579), Expect = 6e-61
 Identities = 109/261 (41%), Positives = 137/261 (52%), Gaps = 16/261 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C+ G C C+ GF G DCS+  CP  CSQRG    G C C+PG+ G +C 
Sbjct: 220  SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG 279

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C NG+C C  GY G+ CG   CP   CS  G C +G CVC  G+
Sbjct: 280  MR--SCP-RGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRG-CSQRGRCKDGRCVCDPGY 335

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCGT       C  DC G G   VD + C C   ++GEDCS   C  +C   GRC  
Sbjct: 336  TGEDCGTRS-----CPWDC-GEGGRCVDGR-CVCWPGYTGEDCSTRTCPRDCRGRGRCED 388

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SG+ C VR C   C + G+C++G C+C  G+ G  C    CPR C G G+C
Sbjct: 389  GECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC 448

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
                     C C  G+ G DC
Sbjct: 449  E-----NGVCVCNAGYSGEDC 464



 Score =  235 bits (576), Expect = 1e-60
 Identities = 120/310 (38%), Positives = 152/310 (49%), Gaps = 24/310 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C  G C C  G+ GDDC    CP  C+QRG   +G C C PG+ G +
Sbjct: 373  TRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTD 432

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C  R   C   DC G G C NG C C  GY G+ CG   CP   C G G C  G C+C  
Sbjct: 433  CGSR--ACP-RDCRGRGRCENGVCVCNAGYSGEDCGVRSCP-GDCRGRGRCESGRCMCWP 488

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCGT       C  DC G G   VD + C C+  ++GEDC    C  +C  HG C
Sbjct: 489  GYTGRDCGTR-----ACPGDCRGRGRC-VDGR-CVCNPGFTGEDCGSRRCPGDCRGHGLC 541

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
                C C AG+SGE CS R C   C   GQC +G C+C  G++G  C +  CP  C+ HG
Sbjct: 542  EDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHG 601

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQ 1174
             C+   DG   C C++G+   DC+    + C     ++  G   CE+  C   P   +  
Sbjct: 602  VCQ---DG--VCICWEGYVSEDCSI---RTC----PSNCHGRGRCEEGRCLCDPG-YTGP 648

Query: 1175 LCVSSPKPTD 1184
             C +   P D
Sbjct: 649  TCATRMCPAD 658



 Score =  231 bits (564), Expect = 4e-59
 Identities = 113/293 (38%), Positives = 138/293 (47%), Gaps = 28/293 (9%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C  G C C PG+ G DC    CP  C  RG  ++G C CNPG+ G++C 
Sbjct: 468  SCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG 527

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
             R   C   DC GHG C +G C C  GY G+ C    CP   C G G C++G CVC+ G+
Sbjct: 528  SRR--CP-GDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGY 583

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG       QC  DCS HG        C C   +  EDCS   C   C   GRC  
Sbjct: 584  SGEDCGVR-----QCPNDCSQHGV--CQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEE 636

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE-----GCPRSCA 1111
              C C  G++G  C+ R+C A C   G+C  G CLC  G+ G  C  E      CP  C 
Sbjct: 637  GRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCG 696

Query: 1112 GHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                CR       +C C +G+ GPDC     Q C      D  G  +C D  C
Sbjct: 697  PRELCRAG-----QCVCVEGFRGPDCAI---QTC----PGDCRGRGECHDGSC 737



 Score =  223 bits (545), Expect = 8e-57
 Identities = 103/260 (39%), Positives = 129/260 (49%), Gaps = 16/260 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C G+G C  G C C  G+ G+DC    CP  C  RG   +G C C PG+ G++C  
Sbjct: 438  CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 497

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC G G CV+G+C C  G+ G+ CG   CP   C GHG C +G CVC  G+ 
Sbjct: 498  R--ACP-GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGD-CRGHGLCEDGVCVCDAGYS 553

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC T       C   C G G   +D + C C   +SGEDC    C  +C  HG C   
Sbjct: 554  GEDCSTRS-----CPGGCRGRGQC-LDGR-CVCEDGYSGEDCGVRQCPNDCSQHGVCQDG 606

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+  E CS+R C + C   G+C+ G CLC  G+ G  C    CP  C G G+C 
Sbjct: 607  VCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC- 665

Query: 1118 VDNDGRWECKCFDGWDGPDC 1137
                 +  C C  G+ G DC
Sbjct: 666  ----VQGVCLCHVGYGGEDC 681



 Score =  218 bits (532), Expect = 3e-55
 Identities = 103/278 (37%), Positives = 133/278 (47%), Gaps = 16/278 (5%)

Query: 860  DPQEISFVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEY 919
            DP +           + +CP+ C+ +G C+ G C C PG+ G  C    CP  C  RG  
Sbjct: 172  DPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRC 231

Query: 920  INGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTC 979
            + G C C  G+ G +CS R   C    C+  G C  G+C C  GY G  CG   CP   C
Sbjct: 232  VQGVCVCRAGFSGPDCSQR--SCP-RGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPR-GC 287

Query: 980  SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
            S  G C  G CVC  G+ G DCG        C   CS  G        C C   ++GEDC
Sbjct: 288  SQRGRCENGRCVCNPGYTGEDCGVR-----SCPRGCSQRGR--CKDGRCVCDPGYTGEDC 340

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR 1099
                C  +CG  GRCV   C C  G++GE CS R C   C   G+C++G C+C +G++G 
Sbjct: 341  GTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGD 400

Query: 1100 HCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +  CP  C   G+C    DGR  C C+ G+ G DC
Sbjct: 401  DCGVRSCPGDCNQRGRC---EDGR--CVCWPGYTGTDC 433



 Score =  215 bits (524), Expect = 3e-54
 Identities = 99/268 (36%), Positives = 132/268 (49%), Gaps = 21/268 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C+ G C C PGF G+DC    CP  C   G   +G C C+ G+ G++
Sbjct: 497  TRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGED 556

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            CS R   C    C G G C++G+C C  GY G+ CG   CP+  CS HG C +G C+C +
Sbjct: 557  CSTR--SCP-GGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWE 612

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+   DC         C  +C G G    +   C C   ++G  C+  +C  +C   GRC
Sbjct: 613  GYVSEDCSIRT-----CPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 665

Query: 1055 VGESCSCAAGWSGEFCS-----VRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS 1109
            V   C C  G+ GE C         C   C     C+ G C+CV G+ G  C ++ CP  
Sbjct: 666  VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD 725

Query: 1110 CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C G G+C   +DG   C C DG+ G DC
Sbjct: 726  CRGRGEC---HDG--SCVCKDGYAGEDC 748



 Score =  190 bits (462), Expect = 9e-47
 Identities = 108/307 (35%), Positives = 134/307 (43%), Gaps = 39/307 (12%)

Query: 893  CQCQPGFGGDDCS---------------KSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C C+PG+GG  CS                  CP  C+ +G  + G C C PG+ G  C  
Sbjct: 159  CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG- 217

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C   DC G G CV G C C  G+ G  C +  CP   CS  G C  G CVC  G+ 
Sbjct: 218  -WPSCP-GDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPR-GCSQRGRCEGGRCVCDPGYT 274

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DCG        C   CS  G    +   C C+  ++GEDC    C   C   GRC   
Sbjct: 275  GDDCGMR-----SCPRGCSQRGR--CENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDG 327

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++GE C  R C   C E G+C +G C+C  G+ G  C+   CPR C G G+C 
Sbjct: 328  RCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRC- 386

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
               DG  EC C  G+ G DC     + C    D ++ G   CED  C   P    +  C 
Sbjct: 387  --EDG--ECICDTGYSGDDCGV---RSCPG--DCNQRG--RCEDGRCVCWPGYTGTD-CG 434

Query: 1178 SSPKPTD 1184
            S   P D
Sbjct: 435  SRACPRD 441



 Score =  188 bits (459), Expect = 2e-46
 Identities = 104/295 (35%), Positives = 132/295 (44%), Gaps = 36/295 (12%)

Query: 885  KGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRG--EYINGECQCNPGWKGKECSLRHDEC 942
            K +C  G C      G  +  ++    LCS  G  +     C C PGW G  CS   D  
Sbjct: 118  KEQCTGGCCPASAQAGTGEQGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTD-A 176

Query: 943  EVP-------------DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGT 989
            E+P             DCN  G CV G+C C  GY G  CG   CP   C G G C++G 
Sbjct: 177  EIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCP-GDCQGRGRCVQGV 235

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECG 1049
            CVC+ G+ G DC         C   CS  G    +   C C   ++G+DC    C   C 
Sbjct: 236  CVCRAGFSGPDCSQR-----SCPRGCSQRGR--CEGGRCVCDPGYTGDDCGMRSCPRGCS 288

Query: 1050 PHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS 1109
              GRC    C C  G++GE C VR C   C++ G+CK+G C+C  G+ G  C    CP  
Sbjct: 289  QRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD 348

Query: 1110 CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
            C   G+C    DGR  C C+ G+ G DC+T   + C      D  G   CED EC
Sbjct: 349  CGEGGRC---VDGR--CVCWPGYTGEDCST---RTC----PRDCRGRGRCEDGEC 391



 Score =  130 bits (314), Expect = 7e-29
 Identities = 67/169 (39%), Positives = 84/169 (49%), Gaps = 16/169 (9%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPN CS  G C  G C C  G+  +DCS   CP  C  RG    G C C+PG+ G  C+ 
Sbjct: 593  CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 652

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSG----HGFCIEGTCVCK 993
            R   C   DC G G CV G C C  GY G+ CG+ + P   C G       C  G CVC 
Sbjct: 653  RM--CPA-DCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCV 709

Query: 994  KGWKGADCGTMDKDALQCLP-DCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
            +G++G DC      A+Q  P DC G G  +    +C C   ++GEDC +
Sbjct: 710  EGFRGPDC------AIQTCPGDCRGRG--ECHDGSCVCKDGYAGEDCGE 750



 Score =  120 bits (288), Expect = 1e-25
 Identities = 52/142 (36%), Positives = 72/142 (50%), Gaps = 4/142 (2%)

Query: 864  ISFVALVAEEMT-HNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYING 922
            I +   V+E+ +   CP+ C G+G C  G C C PG+ G  C+  +CP  C  RG  + G
Sbjct: 609  ICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQG 668

Query: 923  ECQCNPGWKGKECSLRHDECEV--PDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCS 980
             C C+ G+ G++C             C     C  G+C CV G++G  C    CP   C 
Sbjct: 669  VCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD-CR 727

Query: 981  GHGFCIEGTCVCKKGWKGADCG 1002
            G G C +G+CVCK G+ G DCG
Sbjct: 728  GRGECHDGSCVCKDGYAGEDCG 749



 Score =  113 bits (273), Expect = 7e-24
 Identities = 71/206 (34%), Positives = 92/206 (44%), Gaps = 20/206 (9%)

Query: 979  CSGHG-FCIEG-TCVCKKGWKGADCG--TMDKDALQCLPDCSGHGTFDVDTQ------TC 1028
            CS HG F +   TC C+ GW G  C   T  +      P  SG    D + Q       C
Sbjct: 146  CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 205

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C   ++G  C    C  +C   GRCV   C C AG+SG  CS R C   C++ G+C+ G
Sbjct: 206  VCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGG 265

Query: 1089 TCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
             C+C  G+ G  C +  CPR C+  G+C    +GR  C C  G+ G DC           
Sbjct: 266  RCVCDPGYTGDDCGMRSCPRGCSQRGRC---ENGR--CVCNPGYTGEDCGVRSCPRGCSQ 320

Query: 1149 RDNDKDGLVDCEDP----ECCQSPAC 1170
            R   KDG   C DP    E C + +C
Sbjct: 321  RGRCKDGRCVC-DPGYTGEDCGTRSC 345



 Score = 91.5 bits (217), Expect = 4e-17
 Identities = 41/102 (40%), Positives = 55/102 (53%), Gaps = 8/102 (7%)

Query: 875 THNCPNGCSGKGECLMGHCQCQPGFGGDDCSK-----SVCPVLCSQRGEYINGECQCNPG 929
           T  CP  C G+G C+ G C C  G+GG+DC +     S CP  C  R     G+C C  G
Sbjct: 652 TRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEG 711

Query: 930 WKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGE 971
           ++G +C+++   C   DC G G C +G C C  GY G+ CGE
Sbjct: 712 FRGPDCAIQ--TCP-GDCRGRGECHDGSCVCKDGYAGEDCGE 750


>U89337-3|AAB47488.1| 4289|Homo sapiens tenascin X protein.
          Length = 4289

 Score =  245 bits (600), Expect = 2e-63
 Identities = 109/263 (41%), Positives = 142/263 (53%), Gaps = 16/263 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C+ +G C  G C C PG+ G DC    CP  C  RG   NG C CN G+ G++C 
Sbjct: 403  SCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCG 462

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C   DC G G C +G+C C  GY G+ CG   CP   C G G C++G CVC  G+
Sbjct: 463  VR--SCP-GDCRGRGRCESGRCMCWPGYTGRDCGTRACPGD-CRGRGRCVDGRCVCNPGF 518

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG+      +C  DC GHG    +   C C A +SGEDCS   C   C   G+C+ 
Sbjct: 519  TGEDCGSR-----RCPGDCRGHGL--CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SGE C VR C   C++HG C++G C+C  G+    C++  CP +C G G+C
Sbjct: 572  GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 631

Query: 1117 RVDNDGRWECKCFDGWDGPDCTT 1139
                +GR  C C  G+ GP C T
Sbjct: 632  ---EEGR--CLCDPGYTGPTCAT 649



 Score =  238 bits (582), Expect = 3e-61
 Identities = 119/308 (38%), Positives = 154/308 (50%), Gaps = 24/308 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP GCS +G C  G C C PG+ GDDC    CP  CSQRG   NG C CNPG+ G++C 
Sbjct: 248  SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C +G+C C  GY G+ CG   CP   C   G C++G CVC  G+
Sbjct: 308  VR--SCP-RGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD-CGEGGRCVDGRCVCWPGY 363

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC T       C  DC G G  + D + C C   +SG+DC    C  +C   GRC  
Sbjct: 364  TGEDCSTRT-----CPRDCRGRGRCE-DGE-CICDTGYSGDDCGVRSCPGDCNQRGRCED 416

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C  R C   C   G+C+NG C+C +G++G  C +  CP  C G G+C
Sbjct: 417  GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476

Query: 1117 RVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                 GR  C C+ G+ G DC T   + C      D  G   C D  C  +P   + + C
Sbjct: 477  ---ESGR--CMCWPGYTGRDCGT---RAC----PGDCRGRGRCVDGRCVCNPGF-TGEDC 523

Query: 1177 VSSPKPTD 1184
             S   P D
Sbjct: 524  GSRRCPGD 531



 Score =  237 bits (581), Expect = 3e-61
 Identities = 108/263 (41%), Positives = 135/263 (51%), Gaps = 16/263 (6%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T +CP  C   G C+ G C C PG+ G+DCS   CP  C  RG   +GEC C+ G+ G +
Sbjct: 339  TRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDD 398

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C +R   C   DCN  G C +G+C C  GY G  CG   CP   C G G C  G CVC  
Sbjct: 399  CGVR--SCP-GDCNQRGRCEDGRCVCWPGYTGTDCGSRACPR-DCRGRGRCENGVCVCNA 454

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCG        C  DC G G    ++  C C   ++G DC    C  +C   GRC
Sbjct: 455  GYSGEDCGVR-----SCPGDCRGRGR--CESGRCMCWPGYTGRDCGTRACPGDCRGRGRC 507

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
            V   C C  G++GE C  R C   C  HG C++G C+C +G++G  C+   CP  C G G
Sbjct: 508  VDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRG 567

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
            QC    DGR  C C DG+ G DC
Sbjct: 568  QCL---DGR--CVCEDGYSGEDC 585



 Score =  237 bits (579), Expect = 6e-61
 Identities = 109/261 (41%), Positives = 137/261 (52%), Gaps = 16/261 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C+ G C C+ GF G DCS+  CP  CSQRG    G C C+PG+ G +C 
Sbjct: 217  SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG 276

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C NG+C C  GY G+ CG   CP   CS  G C +G CVC  G+
Sbjct: 277  MR--SCP-RGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRG-CSQRGRCKDGRCVCDPGY 332

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCGT       C  DC G G   VD + C C   ++GEDCS   C  +C   GRC  
Sbjct: 333  TGEDCGTRS-----CPWDC-GEGGRCVDGR-CVCWPGYTGEDCSTRTCPRDCRGRGRCED 385

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SG+ C VR C   C + G+C++G C+C  G+ G  C    CPR C G G+C
Sbjct: 386  GECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC 445

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
                     C C  G+ G DC
Sbjct: 446  E-----NGVCVCNAGYSGEDC 461



 Score =  235 bits (576), Expect = 1e-60
 Identities = 120/310 (38%), Positives = 152/310 (49%), Gaps = 24/310 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C  G C C  G+ GDDC    CP  C+QRG   +G C C PG+ G +
Sbjct: 370  TRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTD 429

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C  R   C   DC G G C NG C C  GY G+ CG   CP   C G G C  G C+C  
Sbjct: 430  CGSR--ACP-RDCRGRGRCENGVCVCNAGYSGEDCGVRSCP-GDCRGRGRCESGRCMCWP 485

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCGT       C  DC G G   VD + C C+  ++GEDC    C  +C  HG C
Sbjct: 486  GYTGRDCGTR-----ACPGDCRGRGRC-VDGR-CVCNPGFTGEDCGSRRCPGDCRGHGLC 538

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
                C C AG+SGE CS R C   C   GQC +G C+C  G++G  C +  CP  C+ HG
Sbjct: 539  EDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHG 598

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQ 1174
             C+   DG   C C++G+   DC+    + C     ++  G   CE+  C   P   +  
Sbjct: 599  VCQ---DG--VCICWEGYVSEDCSI---RTC----PSNCHGRGRCEEGRCLCDPG-YTGP 645

Query: 1175 LCVSSPKPTD 1184
             C +   P D
Sbjct: 646  TCATRMCPAD 655



 Score =  231 bits (564), Expect = 4e-59
 Identities = 113/293 (38%), Positives = 138/293 (47%), Gaps = 28/293 (9%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C  G C C PG+ G DC    CP  C  RG  ++G C CNPG+ G++C 
Sbjct: 465  SCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG 524

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
             R   C   DC GHG C +G C C  GY G+ C    CP   C G G C++G CVC+ G+
Sbjct: 525  SRR--CP-GDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGY 580

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG       QC  DCS HG        C C   +  EDCS   C   C   GRC  
Sbjct: 581  SGEDCGVR-----QCPNDCSQHGV--CQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEE 633

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE-----GCPRSCA 1111
              C C  G++G  C+ R+C A C   G+C  G CLC  G+ G  C  E      CP  C 
Sbjct: 634  GRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCG 693

Query: 1112 GHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                CR       +C C +G+ GPDC     Q C      D  G  +C D  C
Sbjct: 694  PRELCRAG-----QCVCVEGFRGPDCAI---QTC----PGDCRGRGECHDGSC 734



 Score =  223 bits (545), Expect = 8e-57
 Identities = 103/260 (39%), Positives = 129/260 (49%), Gaps = 16/260 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C G+G C  G C C  G+ G+DC    CP  C  RG   +G C C PG+ G++C  
Sbjct: 435  CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC G G CV+G+C C  G+ G+ CG   CP   C GHG C +G CVC  G+ 
Sbjct: 495  R--ACP-GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGD-CRGHGLCEDGVCVCDAGYS 550

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC T       C   C G G   +D + C C   +SGEDC    C  +C  HG C   
Sbjct: 551  GEDCSTRS-----CPGGCRGRGQC-LDGR-CVCEDGYSGEDCGVRQCPNDCSQHGVCQDG 603

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+  E CS+R C + C   G+C+ G CLC  G+ G  C    CP  C G G+C 
Sbjct: 604  VCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC- 662

Query: 1118 VDNDGRWECKCFDGWDGPDC 1137
                 +  C C  G+ G DC
Sbjct: 663  ----VQGVCLCHVGYGGEDC 678



 Score =  218 bits (532), Expect = 3e-55
 Identities = 103/278 (37%), Positives = 133/278 (47%), Gaps = 16/278 (5%)

Query: 860  DPQEISFVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEY 919
            DP +           + +CP+ C+ +G C+ G C C PG+ G  C    CP  C  RG  
Sbjct: 169  DPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRC 228

Query: 920  INGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTC 979
            + G C C  G+ G +CS R   C    C+  G C  G+C C  GY G  CG   CP   C
Sbjct: 229  VQGVCVCRAGFSGPDCSQR--SCP-RGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPR-GC 284

Query: 980  SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
            S  G C  G CVC  G+ G DCG        C   CS  G        C C   ++GEDC
Sbjct: 285  SQRGRCENGRCVCNPGYTGEDCGVR-----SCPRGCSQRGR--CKDGRCVCDPGYTGEDC 337

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR 1099
                C  +CG  GRCV   C C  G++GE CS R C   C   G+C++G C+C +G++G 
Sbjct: 338  GTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGD 397

Query: 1100 HCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +  CP  C   G+C    DGR  C C+ G+ G DC
Sbjct: 398  DCGVRSCPGDCNQRGRC---EDGR--CVCWPGYTGTDC 430



 Score =  215 bits (524), Expect = 3e-54
 Identities = 99/268 (36%), Positives = 132/268 (49%), Gaps = 21/268 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C+ G C C PGF G+DC    CP  C   G   +G C C+ G+ G++
Sbjct: 494  TRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGED 553

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            CS R   C    C G G C++G+C C  GY G+ CG   CP+  CS HG C +G C+C +
Sbjct: 554  CSTR--SCP-GGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWE 609

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+   DC         C  +C G G    +   C C   ++G  C+  +C  +C   GRC
Sbjct: 610  GYVSEDCSIRT-----CPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662

Query: 1055 VGESCSCAAGWSGEFCS-----VRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS 1109
            V   C C  G+ GE C         C   C     C+ G C+CV G+ G  C ++ CP  
Sbjct: 663  VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD 722

Query: 1110 CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C G G+C   +DG   C C DG+ G DC
Sbjct: 723  CRGRGEC---HDG--SCVCKDGYAGEDC 745



 Score =  190 bits (462), Expect = 9e-47
 Identities = 108/307 (35%), Positives = 134/307 (43%), Gaps = 39/307 (12%)

Query: 893  CQCQPGFGGDDCS---------------KSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C C+PG+GG  CS                  CP  C+ +G  + G C C PG+ G  C  
Sbjct: 156  CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG- 214

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C   DC G G CV G C C  G+ G  C +  CP   CS  G C  G CVC  G+ 
Sbjct: 215  -WPSCP-GDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPR-GCSQRGRCEGGRCVCDPGYT 271

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DCG        C   CS  G    +   C C+  ++GEDC    C   C   GRC   
Sbjct: 272  GDDCGMR-----SCPRGCSQRGR--CENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDG 324

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++GE C  R C   C E G+C +G C+C  G+ G  C+   CPR C G G+C 
Sbjct: 325  RCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRC- 383

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
               DG  EC C  G+ G DC     + C    D ++ G   CED  C   P    +  C 
Sbjct: 384  --EDG--ECICDTGYSGDDCGV---RSCPG--DCNQRG--RCEDGRCVCWPGYTGTD-CG 431

Query: 1178 SSPKPTD 1184
            S   P D
Sbjct: 432  SRACPRD 438



 Score =  188 bits (459), Expect = 2e-46
 Identities = 88/246 (35%), Positives = 117/246 (47%), Gaps = 16/246 (6%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            +  CP  C G G C  G C C  G+ G+DCS   CP  C  RG+ ++G C C  G+ G++
Sbjct: 525  SRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGED 584

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C +R  +C   DC+ HG C +G C C  GY  + C    CP   C G G C EG C+C  
Sbjct: 585  CGVR--QCP-NDCSQHGVCQDGVCICWEGYVSEDCSIRTCPS-NCHGRGRCEEGRCLCDP 640

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE-----VCSLECG 1049
            G+ G  C T       C  DC G G        C CH  + GEDC +E      C   CG
Sbjct: 641  GYTGPTCATR-----MCPADCRGRGR--CVQGVCLCHVGYGGEDCGQEEPPASACPGGCG 693

Query: 1050 PHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS 1109
            P   C    C C  G+ G  C+++ C   C   G+C +G+C+C  G+ G  C     P S
Sbjct: 694  PRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEARVPSS 753

Query: 1110 CAGHGQ 1115
             + + Q
Sbjct: 754  ASAYDQ 759



 Score =  113 bits (273), Expect = 7e-24
 Identities = 71/206 (34%), Positives = 92/206 (44%), Gaps = 20/206 (9%)

Query: 979  CSGHG-FCIEG-TCVCKKGWKGADCG--TMDKDALQCLPDCSGHGTFDVDTQ------TC 1028
            CS HG F +   TC C+ GW G  C   T  +      P  SG    D + Q       C
Sbjct: 143  CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C   ++G  C    C  +C   GRCV   C C AG+SG  CS R C   C++ G+C+ G
Sbjct: 203  VCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGG 262

Query: 1089 TCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
             C+C  G+ G  C +  CPR C+  G+C    +GR  C C  G+ G DC           
Sbjct: 263  RCVCDPGYTGDDCGMRSCPRGCSQRGRC---ENGR--CVCNPGYTGEDCGVRSCPRGCSQ 317

Query: 1149 RDNDKDGLVDCEDP----ECCQSPAC 1170
            R   KDG   C DP    E C + +C
Sbjct: 318  RGRCKDGRCVC-DPGYTGEDCGTRSC 342


>AL772248-1|CAI18078.1| 4222|Homo sapiens tenascin XB protein.
          Length = 4222

 Score =  245 bits (600), Expect = 2e-63
 Identities = 109/263 (41%), Positives = 142/263 (53%), Gaps = 16/263 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C+ +G C  G C C PG+ G DC    CP  C  RG   NG C CN G+ G++C 
Sbjct: 403  SCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCG 462

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C   DC G G C +G+C C  GY G+ CG   CP   C G G C++G CVC  G+
Sbjct: 463  VR--SCP-GDCRGRGRCESGRCMCWPGYTGRDCGTRACPGD-CRGRGRCVDGRCVCNPGF 518

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG+      +C  DC GHG    +   C C A +SGEDCS   C   C   G+C+ 
Sbjct: 519  TGEDCGSR-----RCPGDCRGHGL--CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SGE C VR C   C++HG C++G C+C  G+    C++  CP +C G G+C
Sbjct: 572  GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 631

Query: 1117 RVDNDGRWECKCFDGWDGPDCTT 1139
                +GR  C C  G+ GP C T
Sbjct: 632  ---EEGR--CLCDPGYTGPTCAT 649



 Score =  238 bits (582), Expect = 3e-61
 Identities = 119/308 (38%), Positives = 154/308 (50%), Gaps = 24/308 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP GCS +G C  G C C PG+ GDDC    CP  CSQRG   NG C CNPG+ G++C 
Sbjct: 248  SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C +G+C C  GY G+ CG   CP   C   G C++G CVC  G+
Sbjct: 308  VR--SCP-RGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD-CGEGGRCVDGRCVCWPGY 363

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC T       C  DC G G  + D + C C   +SG+DC    C  +C   GRC  
Sbjct: 364  TGEDCSTRT-----CPRDCRGRGRCE-DGE-CICDTGYSGDDCGVRSCPGDCNQRGRCED 416

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C  R C   C   G+C+NG C+C +G++G  C +  CP  C G G+C
Sbjct: 417  GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476

Query: 1117 RVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                 GR  C C+ G+ G DC T   + C      D  G   C D  C  +P   + + C
Sbjct: 477  ---ESGR--CMCWPGYTGRDCGT---RAC----PGDCRGRGRCVDGRCVCNPGF-TGEDC 523

Query: 1177 VSSPKPTD 1184
             S   P D
Sbjct: 524  GSRRCPGD 531



 Score =  237 bits (581), Expect = 3e-61
 Identities = 108/263 (41%), Positives = 135/263 (51%), Gaps = 16/263 (6%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T +CP  C   G C+ G C C PG+ G+DCS   CP  C  RG   +GEC C+ G+ G +
Sbjct: 339  TRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDD 398

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C +R   C   DCN  G C +G+C C  GY G  CG   CP   C G G C  G CVC  
Sbjct: 399  CGVR--SCP-GDCNQRGRCEDGRCVCWPGYTGTDCGSRACPR-DCRGRGRCENGVCVCNA 454

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCG        C  DC G G    ++  C C   ++G DC    C  +C   GRC
Sbjct: 455  GYSGEDCGVR-----SCPGDCRGRGR--CESGRCMCWPGYTGRDCGTRACPGDCRGRGRC 507

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
            V   C C  G++GE C  R C   C  HG C++G C+C +G++G  C+   CP  C G G
Sbjct: 508  VDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRG 567

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
            QC    DGR  C C DG+ G DC
Sbjct: 568  QCL---DGR--CVCEDGYSGEDC 585



 Score =  237 bits (579), Expect = 6e-61
 Identities = 109/261 (41%), Positives = 137/261 (52%), Gaps = 16/261 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C+ G C C+ GF G DCS+  CP  CSQRG    G C C+PG+ G +C 
Sbjct: 217  SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG 276

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C NG+C C  GY G+ CG   CP   CS  G C +G CVC  G+
Sbjct: 277  MR--SCP-RGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRG-CSQRGRCKDGRCVCDPGY 332

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCGT       C  DC G G   VD + C C   ++GEDCS   C  +C   GRC  
Sbjct: 333  TGEDCGTRS-----CPWDC-GEGGRCVDGR-CVCWPGYTGEDCSTRTCPRDCRGRGRCED 385

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SG+ C VR C   C + G+C++G C+C  G+ G  C    CPR C G G+C
Sbjct: 386  GECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC 445

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
                     C C  G+ G DC
Sbjct: 446  E-----NGVCVCNAGYSGEDC 461



 Score =  235 bits (576), Expect = 1e-60
 Identities = 120/310 (38%), Positives = 152/310 (49%), Gaps = 24/310 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C  G C C  G+ GDDC    CP  C+QRG   +G C C PG+ G +
Sbjct: 370  TRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTD 429

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C  R   C   DC G G C NG C C  GY G+ CG   CP   C G G C  G C+C  
Sbjct: 430  CGSR--ACP-RDCRGRGRCENGVCVCNAGYSGEDCGVRSCP-GDCRGRGRCESGRCMCWP 485

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCGT       C  DC G G   VD + C C+  ++GEDC    C  +C  HG C
Sbjct: 486  GYTGRDCGTR-----ACPGDCRGRGRC-VDGR-CVCNPGFTGEDCGSRRCPGDCRGHGLC 538

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
                C C AG+SGE CS R C   C   GQC +G C+C  G++G  C +  CP  C+ HG
Sbjct: 539  EDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHG 598

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQ 1174
             C+   DG   C C++G+   DC+    + C     ++  G   CE+  C   P   +  
Sbjct: 599  VCQ---DG--VCICWEGYVSEDCSI---RTC----PSNCHGRGRCEEGRCLCDPG-YTGP 645

Query: 1175 LCVSSPKPTD 1184
             C +   P D
Sbjct: 646  TCATRMCPAD 655



 Score =  231 bits (564), Expect = 4e-59
 Identities = 113/293 (38%), Positives = 138/293 (47%), Gaps = 28/293 (9%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C  G C C PG+ G DC    CP  C  RG  ++G C CNPG+ G++C 
Sbjct: 465  SCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG 524

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
             R   C   DC GHG C +G C C  GY G+ C    CP   C G G C++G CVC+ G+
Sbjct: 525  SRR--CP-GDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGY 580

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG       QC  DCS HG        C C   +  EDCS   C   C   GRC  
Sbjct: 581  SGEDCGVR-----QCPNDCSQHGV--CQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEE 633

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE-----GCPRSCA 1111
              C C  G++G  C+ R+C A C   G+C  G CLC  G+ G  C  E      CP  C 
Sbjct: 634  GRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCG 693

Query: 1112 GHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                CR       +C C +G+ GPDC     Q C      D  G  +C D  C
Sbjct: 694  PRELCRAG-----QCVCVEGFRGPDCAI---QTC----PGDCRGRGECHDGSC 734



 Score =  223 bits (545), Expect = 8e-57
 Identities = 103/260 (39%), Positives = 129/260 (49%), Gaps = 16/260 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C G+G C  G C C  G+ G+DC    CP  C  RG   +G C C PG+ G++C  
Sbjct: 435  CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC G G CV+G+C C  G+ G+ CG   CP   C GHG C +G CVC  G+ 
Sbjct: 495  R--ACP-GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGD-CRGHGLCEDGVCVCDAGYS 550

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC T       C   C G G   +D + C C   +SGEDC    C  +C  HG C   
Sbjct: 551  GEDCSTRS-----CPGGCRGRGQC-LDGR-CVCEDGYSGEDCGVRQCPNDCSQHGVCQDG 603

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+  E CS+R C + C   G+C+ G CLC  G+ G  C    CP  C G G+C 
Sbjct: 604  VCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC- 662

Query: 1118 VDNDGRWECKCFDGWDGPDC 1137
                 +  C C  G+ G DC
Sbjct: 663  ----VQGVCLCHVGYGGEDC 678



 Score =  218 bits (532), Expect = 3e-55
 Identities = 103/278 (37%), Positives = 133/278 (47%), Gaps = 16/278 (5%)

Query: 860  DPQEISFVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEY 919
            DP +           + +CP+ C+ +G C+ G C C PG+ G  C    CP  C  RG  
Sbjct: 169  DPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRC 228

Query: 920  INGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTC 979
            + G C C  G+ G +CS R   C    C+  G C  G+C C  GY G  CG   CP   C
Sbjct: 229  VQGVCVCRAGFSGPDCSQR--SCP-RGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPR-GC 284

Query: 980  SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
            S  G C  G CVC  G+ G DCG        C   CS  G        C C   ++GEDC
Sbjct: 285  SQRGRCENGRCVCNPGYTGEDCGVR-----SCPRGCSQRGR--CKDGRCVCDPGYTGEDC 337

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR 1099
                C  +CG  GRCV   C C  G++GE CS R C   C   G+C++G C+C +G++G 
Sbjct: 338  GTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGD 397

Query: 1100 HCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +  CP  C   G+C    DGR  C C+ G+ G DC
Sbjct: 398  DCGVRSCPGDCNQRGRC---EDGR--CVCWPGYTGTDC 430



 Score =  215 bits (524), Expect = 3e-54
 Identities = 99/268 (36%), Positives = 132/268 (49%), Gaps = 21/268 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C+ G C C PGF G+DC    CP  C   G   +G C C+ G+ G++
Sbjct: 494  TRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGED 553

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            CS R   C    C G G C++G+C C  GY G+ CG   CP+  CS HG C +G C+C +
Sbjct: 554  CSTR--SCP-GGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWE 609

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+   DC         C  +C G G    +   C C   ++G  C+  +C  +C   GRC
Sbjct: 610  GYVSEDCSIRT-----CPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662

Query: 1055 VGESCSCAAGWSGEFCS-----VRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS 1109
            V   C C  G+ GE C         C   C     C+ G C+CV G+ G  C ++ CP  
Sbjct: 663  VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD 722

Query: 1110 CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C G G+C   +DG   C C DG+ G DC
Sbjct: 723  CRGRGEC---HDG--SCVCKDGYAGEDC 745



 Score =  190 bits (462), Expect = 9e-47
 Identities = 108/307 (35%), Positives = 134/307 (43%), Gaps = 39/307 (12%)

Query: 893  CQCQPGFGGDDCS---------------KSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C C+PG+GG  CS                  CP  C+ +G  + G C C PG+ G  C  
Sbjct: 156  CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG- 214

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C   DC G G CV G C C  G+ G  C +  CP   CS  G C  G CVC  G+ 
Sbjct: 215  -WPSCP-GDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPR-GCSQRGRCEGGRCVCDPGYT 271

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DCG        C   CS  G    +   C C+  ++GEDC    C   C   GRC   
Sbjct: 272  GDDCGMR-----SCPRGCSQRGR--CENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDG 324

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++GE C  R C   C E G+C +G C+C  G+ G  C+   CPR C G G+C 
Sbjct: 325  RCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRC- 383

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
               DG  EC C  G+ G DC     + C    D ++ G   CED  C   P    +  C 
Sbjct: 384  --EDG--ECICDTGYSGDDCGV---RSCPG--DCNQRG--RCEDGRCVCWPGYTGTD-CG 431

Query: 1178 SSPKPTD 1184
            S   P D
Sbjct: 432  SRACPRD 438



 Score =  136 bits (328), Expect = 2e-30
 Identities = 70/175 (40%), Positives = 89/175 (50%), Gaps = 16/175 (9%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPN CS  G C  G C C  G+  +DCS   CP  C  RG    G C C+PG+ G  C+ 
Sbjct: 590  CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 649

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSG----HGFCIEGTCVCK 993
            R   C   DC G G CV G C C  GY G+ CG+ + P   C G       C  G CVC 
Sbjct: 650  RM--CPA-DCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCV 706

Query: 994  KGWKGADCGTMDKDALQCLP-DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE 1047
            +G++G DC      A+Q  P DC G G  +    +C C   ++GEDC +EV ++E
Sbjct: 707  EGFRGPDC------AIQTCPGDCRGRG--ECHDGSCVCKDGYAGEDCGEEVPTIE 753



 Score =  120 bits (288), Expect = 1e-25
 Identities = 52/142 (36%), Positives = 72/142 (50%), Gaps = 4/142 (2%)

Query: 864  ISFVALVAEEMT-HNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYING 922
            I +   V+E+ +   CP+ C G+G C  G C C PG+ G  C+  +CP  C  RG  + G
Sbjct: 606  ICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQG 665

Query: 923  ECQCNPGWKGKECSLRHDECEV--PDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCS 980
             C C+ G+ G++C             C     C  G+C CV G++G  C    CP   C 
Sbjct: 666  VCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD-CR 724

Query: 981  GHGFCIEGTCVCKKGWKGADCG 1002
            G G C +G+CVCK G+ G DCG
Sbjct: 725  GRGECHDGSCVCKDGYAGEDCG 746



 Score =  113 bits (273), Expect = 7e-24
 Identities = 71/206 (34%), Positives = 92/206 (44%), Gaps = 20/206 (9%)

Query: 979  CSGHG-FCIEG-TCVCKKGWKGADCG--TMDKDALQCLPDCSGHGTFDVDTQ------TC 1028
            CS HG F +   TC C+ GW G  C   T  +      P  SG    D + Q       C
Sbjct: 143  CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C   ++G  C    C  +C   GRCV   C C AG+SG  CS R C   C++ G+C+ G
Sbjct: 203  VCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGG 262

Query: 1089 TCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
             C+C  G+ G  C +  CPR C+  G+C    +GR  C C  G+ G DC           
Sbjct: 263  RCVCDPGYTGDDCGMRSCPRGCSQRGRC---ENGR--CVCNPGYTGEDCGVRSCPRGCSQ 317

Query: 1149 RDNDKDGLVDCEDP----ECCQSPAC 1170
            R   KDG   C DP    E C + +C
Sbjct: 318  RGRCKDGRCVC-DPGYTGEDCGTRSC 342



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 51/148 (34%), Positives = 70/148 (47%), Gaps = 12/148 (8%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSK-----SVCPVLCSQRGEYINGECQCNPG 929
            T  CP  C G+G C+ G C C  G+GG+DC +     S CP  C  R     G+C C  G
Sbjct: 649  TRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEG 708

Query: 930  WKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGT 989
            ++G +C+++   C   DC G G C +G C C  GY G+ CGE     PT  G    +   
Sbjct: 709  FRGPDCAIQ--TCP-GDCRGRGECHDGSCVCKDGYAGEDCGE---EVPTIEGMRMHLLEE 762

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSG 1017
               +  W  A  G +D   +Q +P   G
Sbjct: 763  TTVRTEWTPAP-GPVDAYEIQFIPTTEG 789


>AL662884-1|CAI18332.1| 4222|Homo sapiens tenascin XB protein.
          Length = 4222

 Score =  245 bits (600), Expect = 2e-63
 Identities = 109/263 (41%), Positives = 142/263 (53%), Gaps = 16/263 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C+ +G C  G C C PG+ G DC    CP  C  RG   NG C CN G+ G++C 
Sbjct: 403  SCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCG 462

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C   DC G G C +G+C C  GY G+ CG   CP   C G G C++G CVC  G+
Sbjct: 463  VR--SCP-GDCRGRGRCESGRCMCWPGYTGRDCGTRACPGD-CRGRGRCVDGRCVCNPGF 518

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG+      +C  DC GHG    +   C C A +SGEDCS   C   C   G+C+ 
Sbjct: 519  TGEDCGSR-----RCPGDCRGHGL--CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SGE C VR C   C++HG C++G C+C  G+    C++  CP +C G G+C
Sbjct: 572  GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 631

Query: 1117 RVDNDGRWECKCFDGWDGPDCTT 1139
                +GR  C C  G+ GP C T
Sbjct: 632  ---EEGR--CLCDPGYTGPTCAT 649



 Score =  238 bits (582), Expect = 3e-61
 Identities = 119/308 (38%), Positives = 154/308 (50%), Gaps = 24/308 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP GCS +G C  G C C PG+ GDDC    CP  CSQRG   NG C CNPG+ G++C 
Sbjct: 248  SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C +G+C C  GY G+ CG   CP   C   G C++G CVC  G+
Sbjct: 308  VR--SCP-RGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD-CGEGGRCVDGRCVCWPGY 363

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC T       C  DC G G  + D + C C   +SG+DC    C  +C   GRC  
Sbjct: 364  TGEDCSTRT-----CPRDCRGRGRCE-DGE-CICDTGYSGDDCGVRSCPGDCNQRGRCED 416

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C  R C   C   G+C+NG C+C +G++G  C +  CP  C G G+C
Sbjct: 417  GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476

Query: 1117 RVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                 GR  C C+ G+ G DC T   + C      D  G   C D  C  +P   + + C
Sbjct: 477  ---ESGR--CMCWPGYTGRDCGT---RAC----PGDCRGRGRCVDGRCVCNPGF-TGEDC 523

Query: 1177 VSSPKPTD 1184
             S   P D
Sbjct: 524  GSRRCPGD 531



 Score =  237 bits (581), Expect = 3e-61
 Identities = 108/263 (41%), Positives = 135/263 (51%), Gaps = 16/263 (6%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T +CP  C   G C+ G C C PG+ G+DCS   CP  C  RG   +GEC C+ G+ G +
Sbjct: 339  TRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDD 398

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C +R   C   DCN  G C +G+C C  GY G  CG   CP   C G G C  G CVC  
Sbjct: 399  CGVR--SCP-GDCNQRGRCEDGRCVCWPGYTGTDCGSRACPR-DCRGRGRCENGVCVCNA 454

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCG        C  DC G G    ++  C C   ++G DC    C  +C   GRC
Sbjct: 455  GYSGEDCGVR-----SCPGDCRGRGR--CESGRCMCWPGYTGRDCGTRACPGDCRGRGRC 507

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
            V   C C  G++GE C  R C   C  HG C++G C+C +G++G  C+   CP  C G G
Sbjct: 508  VDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRG 567

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
            QC    DGR  C C DG+ G DC
Sbjct: 568  QCL---DGR--CVCEDGYSGEDC 585



 Score =  237 bits (579), Expect = 6e-61
 Identities = 109/261 (41%), Positives = 137/261 (52%), Gaps = 16/261 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C+ G C C+ GF G DCS+  CP  CSQRG    G C C+PG+ G +C 
Sbjct: 217  SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG 276

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C NG+C C  GY G+ CG   CP   CS  G C +G CVC  G+
Sbjct: 277  MR--SCP-RGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRG-CSQRGRCKDGRCVCDPGY 332

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCGT       C  DC G G   VD + C C   ++GEDCS   C  +C   GRC  
Sbjct: 333  TGEDCGTRS-----CPWDC-GEGGRCVDGR-CVCWPGYTGEDCSTRTCPRDCRGRGRCED 385

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SG+ C VR C   C + G+C++G C+C  G+ G  C    CPR C G G+C
Sbjct: 386  GECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC 445

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
                     C C  G+ G DC
Sbjct: 446  E-----NGVCVCNAGYSGEDC 461



 Score =  235 bits (576), Expect = 1e-60
 Identities = 120/310 (38%), Positives = 152/310 (49%), Gaps = 24/310 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C  G C C  G+ GDDC    CP  C+QRG   +G C C PG+ G +
Sbjct: 370  TRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTD 429

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C  R   C   DC G G C NG C C  GY G+ CG   CP   C G G C  G C+C  
Sbjct: 430  CGSR--ACP-RDCRGRGRCENGVCVCNAGYSGEDCGVRSCP-GDCRGRGRCESGRCMCWP 485

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCGT       C  DC G G   VD + C C+  ++GEDC    C  +C  HG C
Sbjct: 486  GYTGRDCGTR-----ACPGDCRGRGRC-VDGR-CVCNPGFTGEDCGSRRCPGDCRGHGLC 538

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
                C C AG+SGE CS R C   C   GQC +G C+C  G++G  C +  CP  C+ HG
Sbjct: 539  EDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHG 598

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQ 1174
             C+   DG   C C++G+   DC+    + C     ++  G   CE+  C   P   +  
Sbjct: 599  VCQ---DG--VCICWEGYVSEDCSI---RTC----PSNCHGRGRCEEGRCLCDPG-YTGP 645

Query: 1175 LCVSSPKPTD 1184
             C +   P D
Sbjct: 646  TCATRMCPAD 655



 Score =  231 bits (564), Expect = 4e-59
 Identities = 113/293 (38%), Positives = 138/293 (47%), Gaps = 28/293 (9%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C  G C C PG+ G DC    CP  C  RG  ++G C CNPG+ G++C 
Sbjct: 465  SCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG 524

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
             R   C   DC GHG C +G C C  GY G+ C    CP   C G G C++G CVC+ G+
Sbjct: 525  SRR--CP-GDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGY 580

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG       QC  DCS HG        C C   +  EDCS   C   C   GRC  
Sbjct: 581  SGEDCGVR-----QCPNDCSQHGV--CQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEE 633

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE-----GCPRSCA 1111
              C C  G++G  C+ R+C A C   G+C  G CLC  G+ G  C  E      CP  C 
Sbjct: 634  GRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCG 693

Query: 1112 GHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                CR       +C C +G+ GPDC     Q C      D  G  +C D  C
Sbjct: 694  PRELCRAG-----QCVCVEGFRGPDCAI---QTC----PGDCRGRGECHDGSC 734



 Score =  223 bits (545), Expect = 8e-57
 Identities = 103/260 (39%), Positives = 129/260 (49%), Gaps = 16/260 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C G+G C  G C C  G+ G+DC    CP  C  RG   +G C C PG+ G++C  
Sbjct: 435  CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC G G CV+G+C C  G+ G+ CG   CP   C GHG C +G CVC  G+ 
Sbjct: 495  R--ACP-GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGD-CRGHGLCEDGVCVCDAGYS 550

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC T       C   C G G   +D + C C   +SGEDC    C  +C  HG C   
Sbjct: 551  GEDCSTRS-----CPGGCRGRGQC-LDGR-CVCEDGYSGEDCGVRQCPNDCSQHGVCQDG 603

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+  E CS+R C + C   G+C+ G CLC  G+ G  C    CP  C G G+C 
Sbjct: 604  VCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC- 662

Query: 1118 VDNDGRWECKCFDGWDGPDC 1137
                 +  C C  G+ G DC
Sbjct: 663  ----VQGVCLCHVGYGGEDC 678



 Score =  218 bits (532), Expect = 3e-55
 Identities = 103/278 (37%), Positives = 133/278 (47%), Gaps = 16/278 (5%)

Query: 860  DPQEISFVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEY 919
            DP +           + +CP+ C+ +G C+ G C C PG+ G  C    CP  C  RG  
Sbjct: 169  DPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRC 228

Query: 920  INGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTC 979
            + G C C  G+ G +CS R   C    C+  G C  G+C C  GY G  CG   CP   C
Sbjct: 229  VQGVCVCRAGFSGPDCSQR--SCP-RGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPR-GC 284

Query: 980  SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
            S  G C  G CVC  G+ G DCG        C   CS  G        C C   ++GEDC
Sbjct: 285  SQRGRCENGRCVCNPGYTGEDCGVR-----SCPRGCSQRGR--CKDGRCVCDPGYTGEDC 337

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR 1099
                C  +CG  GRCV   C C  G++GE CS R C   C   G+C++G C+C +G++G 
Sbjct: 338  GTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGD 397

Query: 1100 HCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +  CP  C   G+C    DGR  C C+ G+ G DC
Sbjct: 398  DCGVRSCPGDCNQRGRC---EDGR--CVCWPGYTGTDC 430



 Score =  215 bits (524), Expect = 3e-54
 Identities = 99/268 (36%), Positives = 132/268 (49%), Gaps = 21/268 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C+ G C C PGF G+DC    CP  C   G   +G C C+ G+ G++
Sbjct: 494  TRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGED 553

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            CS R   C    C G G C++G+C C  GY G+ CG   CP+  CS HG C +G C+C +
Sbjct: 554  CSTR--SCP-GGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWE 609

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+   DC         C  +C G G    +   C C   ++G  C+  +C  +C   GRC
Sbjct: 610  GYVSEDCSIRT-----CPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662

Query: 1055 VGESCSCAAGWSGEFCS-----VRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS 1109
            V   C C  G+ GE C         C   C     C+ G C+CV G+ G  C ++ CP  
Sbjct: 663  VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD 722

Query: 1110 CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C G G+C   +DG   C C DG+ G DC
Sbjct: 723  CRGRGEC---HDG--SCVCKDGYAGEDC 745



 Score =  190 bits (462), Expect = 9e-47
 Identities = 108/307 (35%), Positives = 134/307 (43%), Gaps = 39/307 (12%)

Query: 893  CQCQPGFGGDDCS---------------KSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C C+PG+GG  CS                  CP  C+ +G  + G C C PG+ G  C  
Sbjct: 156  CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG- 214

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C   DC G G CV G C C  G+ G  C +  CP   CS  G C  G CVC  G+ 
Sbjct: 215  -WPSCP-GDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPR-GCSQRGRCEGGRCVCDPGYT 271

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DCG        C   CS  G    +   C C+  ++GEDC    C   C   GRC   
Sbjct: 272  GDDCGMR-----SCPRGCSQRGR--CENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDG 324

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++GE C  R C   C E G+C +G C+C  G+ G  C+   CPR C G G+C 
Sbjct: 325  RCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRC- 383

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
               DG  EC C  G+ G DC     + C    D ++ G   CED  C   P    +  C 
Sbjct: 384  --EDG--ECICDTGYSGDDCGV---RSCPG--DCNQRG--RCEDGRCVCWPGYTGTD-CG 431

Query: 1178 SSPKPTD 1184
            S   P D
Sbjct: 432  SRACPRD 438



 Score =  136 bits (328), Expect = 2e-30
 Identities = 70/175 (40%), Positives = 89/175 (50%), Gaps = 16/175 (9%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPN CS  G C  G C C  G+  +DCS   CP  C  RG    G C C+PG+ G  C+ 
Sbjct: 590  CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 649

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSG----HGFCIEGTCVCK 993
            R   C   DC G G CV G C C  GY G+ CG+ + P   C G       C  G CVC 
Sbjct: 650  RM--CPA-DCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCV 706

Query: 994  KGWKGADCGTMDKDALQCLP-DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE 1047
            +G++G DC      A+Q  P DC G G  +    +C C   ++GEDC +EV ++E
Sbjct: 707  EGFRGPDC------AIQTCPGDCRGRG--ECHDGSCVCKDGYAGEDCGEEVPTIE 753



 Score =  120 bits (288), Expect = 1e-25
 Identities = 52/142 (36%), Positives = 72/142 (50%), Gaps = 4/142 (2%)

Query: 864  ISFVALVAEEMT-HNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYING 922
            I +   V+E+ +   CP+ C G+G C  G C C PG+ G  C+  +CP  C  RG  + G
Sbjct: 606  ICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQG 665

Query: 923  ECQCNPGWKGKECSLRHDECEV--PDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCS 980
             C C+ G+ G++C             C     C  G+C CV G++G  C    CP   C 
Sbjct: 666  VCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD-CR 724

Query: 981  GHGFCIEGTCVCKKGWKGADCG 1002
            G G C +G+CVCK G+ G DCG
Sbjct: 725  GRGECHDGSCVCKDGYAGEDCG 746



 Score =  113 bits (273), Expect = 7e-24
 Identities = 71/206 (34%), Positives = 92/206 (44%), Gaps = 20/206 (9%)

Query: 979  CSGHG-FCIEG-TCVCKKGWKGADCG--TMDKDALQCLPDCSGHGTFDVDTQ------TC 1028
            CS HG F +   TC C+ GW G  C   T  +      P  SG    D + Q       C
Sbjct: 143  CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C   ++G  C    C  +C   GRCV   C C AG+SG  CS R C   C++ G+C+ G
Sbjct: 203  VCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGG 262

Query: 1089 TCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
             C+C  G+ G  C +  CPR C+  G+C    +GR  C C  G+ G DC           
Sbjct: 263  RCVCDPGYTGDDCGMRSCPRGCSQRGRC---ENGR--CVCNPGYTGEDCGVRSCPRGCSQ 317

Query: 1149 RDNDKDGLVDCEDP----ECCQSPAC 1170
            R   KDG   C DP    E C + +C
Sbjct: 318  RGRCKDGRCVC-DPGYTGEDCGTRSC 342



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 51/148 (34%), Positives = 70/148 (47%), Gaps = 12/148 (8%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSK-----SVCPVLCSQRGEYINGECQCNPG 929
            T  CP  C G+G C+ G C C  G+GG+DC +     S CP  C  R     G+C C  G
Sbjct: 649  TRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEG 708

Query: 930  WKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGT 989
            ++G +C+++   C   DC G G C +G C C  GY G+ CGE     PT  G    +   
Sbjct: 709  FRGPDCAIQ--TCP-GDCRGRGECHDGSCVCKDGYAGEDCGE---EVPTIEGMRMHLLEE 762

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSG 1017
               +  W  A  G +D   +Q +P   G
Sbjct: 763  TTVRTEWTPAP-GPVDAYEIQFIPTTEG 789


>AL662849-16|CAI17471.1| 4222|Homo sapiens tenascin XB protein.
          Length = 4222

 Score =  245 bits (600), Expect = 2e-63
 Identities = 109/263 (41%), Positives = 142/263 (53%), Gaps = 16/263 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C+ +G C  G C C PG+ G DC    CP  C  RG   NG C CN G+ G++C 
Sbjct: 403  SCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCG 462

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C   DC G G C +G+C C  GY G+ CG   CP   C G G C++G CVC  G+
Sbjct: 463  VR--SCP-GDCRGRGRCESGRCMCWPGYTGRDCGTRACPGD-CRGRGRCVDGRCVCNPGF 518

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG+      +C  DC GHG    +   C C A +SGEDCS   C   C   G+C+ 
Sbjct: 519  TGEDCGSR-----RCPGDCRGHGL--CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SGE C VR C   C++HG C++G C+C  G+    C++  CP +C G G+C
Sbjct: 572  GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 631

Query: 1117 RVDNDGRWECKCFDGWDGPDCTT 1139
                +GR  C C  G+ GP C T
Sbjct: 632  ---EEGR--CLCDPGYTGPTCAT 649



 Score =  238 bits (582), Expect = 3e-61
 Identities = 119/308 (38%), Positives = 154/308 (50%), Gaps = 24/308 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP GCS +G C  G C C PG+ GDDC    CP  CSQRG   NG C CNPG+ G++C 
Sbjct: 248  SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYAGEDCG 307

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C +G+C C  GY G+ CG   CP   C   G C++G CVC  G+
Sbjct: 308  VR--SCP-RGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD-CGEGGRCVDGRCVCWPGY 363

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC T       C  DC G G  + D + C C   +SG+DC    C  +C   GRC  
Sbjct: 364  TGEDCSTRT-----CPRDCRGRGRCE-DGE-CICDTGYSGDDCGVRSCPGDCNQRGRCED 416

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C  R C   C   G+C+NG C+C +G++G  C +  CP  C G G+C
Sbjct: 417  GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476

Query: 1117 RVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                 GR  C C+ G+ G DC T   + C      D  G   C D  C  +P   + + C
Sbjct: 477  ---ESGR--CMCWPGYTGRDCGT---RAC----PGDCRGRGRCVDGRCVCNPGF-TGEDC 523

Query: 1177 VSSPKPTD 1184
             S   P D
Sbjct: 524  GSRRCPGD 531



 Score =  237 bits (581), Expect = 3e-61
 Identities = 108/263 (41%), Positives = 135/263 (51%), Gaps = 16/263 (6%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T +CP  C   G C+ G C C PG+ G+DCS   CP  C  RG   +GEC C+ G+ G +
Sbjct: 339  TRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDD 398

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C +R   C   DCN  G C +G+C C  GY G  CG   CP   C G G C  G CVC  
Sbjct: 399  CGVR--SCP-GDCNQRGRCEDGRCVCWPGYTGTDCGSRACPR-DCRGRGRCENGVCVCNA 454

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCG        C  DC G G    ++  C C   ++G DC    C  +C   GRC
Sbjct: 455  GYSGEDCGVR-----SCPGDCRGRGR--CESGRCMCWPGYTGRDCGTRACPGDCRGRGRC 507

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
            V   C C  G++GE C  R C   C  HG C++G C+C +G++G  C+   CP  C G G
Sbjct: 508  VDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRG 567

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
            QC    DGR  C C DG+ G DC
Sbjct: 568  QCL---DGR--CVCEDGYSGEDC 585



 Score =  237 bits (579), Expect = 6e-61
 Identities = 109/261 (41%), Positives = 137/261 (52%), Gaps = 16/261 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C+ G C C+ GF G DCS+  CP  CSQRG    G C C+PG+ G +C 
Sbjct: 217  SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG 276

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C NG+C C  GY G+ CG   CP   CS  G C +G CVC  G+
Sbjct: 277  MR--SCP-RGCSQRGRCENGRCVCNPGYAGEDCGVRSCPRG-CSQRGRCKDGRCVCDPGY 332

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCGT       C  DC G G   VD + C C   ++GEDCS   C  +C   GRC  
Sbjct: 333  TGEDCGTRS-----CPWDC-GEGGRCVDGR-CVCWPGYTGEDCSTRTCPRDCRGRGRCED 385

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SG+ C VR C   C + G+C++G C+C  G+ G  C    CPR C G G+C
Sbjct: 386  GECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC 445

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
                     C C  G+ G DC
Sbjct: 446  E-----NGVCVCNAGYSGEDC 461



 Score =  235 bits (576), Expect = 1e-60
 Identities = 120/310 (38%), Positives = 152/310 (49%), Gaps = 24/310 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C  G C C  G+ GDDC    CP  C+QRG   +G C C PG+ G +
Sbjct: 370  TRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTD 429

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C  R   C   DC G G C NG C C  GY G+ CG   CP   C G G C  G C+C  
Sbjct: 430  CGSR--ACP-RDCRGRGRCENGVCVCNAGYSGEDCGVRSCP-GDCRGRGRCESGRCMCWP 485

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCGT       C  DC G G   VD + C C+  ++GEDC    C  +C  HG C
Sbjct: 486  GYTGRDCGTR-----ACPGDCRGRGRC-VDGR-CVCNPGFTGEDCGSRRCPGDCRGHGLC 538

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
                C C AG+SGE CS R C   C   GQC +G C+C  G++G  C +  CP  C+ HG
Sbjct: 539  EDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHG 598

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQ 1174
             C+   DG   C C++G+   DC+    + C     ++  G   CE+  C   P   +  
Sbjct: 599  VCQ---DG--VCICWEGYVSEDCSI---RTC----PSNCHGRGRCEEGRCLCDPG-YTGP 645

Query: 1175 LCVSSPKPTD 1184
             C +   P D
Sbjct: 646  TCATRMCPAD 655



 Score =  231 bits (564), Expect = 4e-59
 Identities = 113/293 (38%), Positives = 138/293 (47%), Gaps = 28/293 (9%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C  G C C PG+ G DC    CP  C  RG  ++G C CNPG+ G++C 
Sbjct: 465  SCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG 524

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
             R   C   DC GHG C +G C C  GY G+ C    CP   C G G C++G CVC+ G+
Sbjct: 525  SRR--CP-GDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGY 580

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG       QC  DCS HG        C C   +  EDCS   C   C   GRC  
Sbjct: 581  SGEDCGVR-----QCPNDCSQHGV--CQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEE 633

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE-----GCPRSCA 1111
              C C  G++G  C+ R+C A C   G+C  G CLC  G+ G  C  E      CP  C 
Sbjct: 634  GRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCG 693

Query: 1112 GHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                CR       +C C +G+ GPDC     Q C      D  G  +C D  C
Sbjct: 694  PRELCRAG-----QCVCVEGFRGPDCAI---QTC----PGDCRGRGECHDGSC 734



 Score =  223 bits (545), Expect = 8e-57
 Identities = 103/260 (39%), Positives = 129/260 (49%), Gaps = 16/260 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C G+G C  G C C  G+ G+DC    CP  C  RG   +G C C PG+ G++C  
Sbjct: 435  CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC G G CV+G+C C  G+ G+ CG   CP   C GHG C +G CVC  G+ 
Sbjct: 495  R--ACP-GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGD-CRGHGLCEDGVCVCDAGYS 550

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC T       C   C G G   +D + C C   +SGEDC    C  +C  HG C   
Sbjct: 551  GEDCSTRS-----CPGGCRGRGQC-LDGR-CVCEDGYSGEDCGVRQCPNDCSQHGVCQDG 603

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+  E CS+R C + C   G+C+ G CLC  G+ G  C    CP  C G G+C 
Sbjct: 604  VCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC- 662

Query: 1118 VDNDGRWECKCFDGWDGPDC 1137
                 +  C C  G+ G DC
Sbjct: 663  ----VQGVCLCHVGYGGEDC 678



 Score =  218 bits (532), Expect = 3e-55
 Identities = 103/278 (37%), Positives = 133/278 (47%), Gaps = 16/278 (5%)

Query: 860  DPQEISFVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEY 919
            DP +           + +CP+ C+ +G C+ G C C PG+ G  C    CP  C  RG  
Sbjct: 169  DPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRC 228

Query: 920  INGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTC 979
            + G C C  G+ G +CS R   C    C+  G C  G+C C  GY G  CG   CP   C
Sbjct: 229  VQGVCVCRAGFSGPDCSQR--SCP-RGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPR-GC 284

Query: 980  SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
            S  G C  G CVC  G+ G DCG        C   CS  G        C C   ++GEDC
Sbjct: 285  SQRGRCENGRCVCNPGYAGEDCGVR-----SCPRGCSQRGR--CKDGRCVCDPGYTGEDC 337

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR 1099
                C  +CG  GRCV   C C  G++GE CS R C   C   G+C++G C+C +G++G 
Sbjct: 338  GTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGD 397

Query: 1100 HCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +  CP  C   G+C    DGR  C C+ G+ G DC
Sbjct: 398  DCGVRSCPGDCNQRGRC---EDGR--CVCWPGYTGTDC 430



 Score =  215 bits (524), Expect = 3e-54
 Identities = 99/268 (36%), Positives = 132/268 (49%), Gaps = 21/268 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C+ G C C PGF G+DC    CP  C   G   +G C C+ G+ G++
Sbjct: 494  TRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGED 553

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            CS R   C    C G G C++G+C C  GY G+ CG   CP+  CS HG C +G C+C +
Sbjct: 554  CSTR--SCP-GGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWE 609

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+   DC         C  +C G G    +   C C   ++G  C+  +C  +C   GRC
Sbjct: 610  GYVSEDCSIRT-----CPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662

Query: 1055 VGESCSCAAGWSGEFCS-----VRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS 1109
            V   C C  G+ GE C         C   C     C+ G C+CV G+ G  C ++ CP  
Sbjct: 663  VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD 722

Query: 1110 CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C G G+C   +DG   C C DG+ G DC
Sbjct: 723  CRGRGEC---HDG--SCVCKDGYAGEDC 745



 Score =  190 bits (462), Expect = 9e-47
 Identities = 108/307 (35%), Positives = 134/307 (43%), Gaps = 39/307 (12%)

Query: 893  CQCQPGFGGDDCS---------------KSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C C+PG+GG  CS                  CP  C+ +G  + G C C PG+ G  C  
Sbjct: 156  CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG- 214

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C   DC G G CV G C C  G+ G  C +  CP   CS  G C  G CVC  G+ 
Sbjct: 215  -WPSCP-GDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPR-GCSQRGRCEGGRCVCDPGYT 271

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DCG        C   CS  G    +   C C+  ++GEDC    C   C   GRC   
Sbjct: 272  GDDCGMR-----SCPRGCSQRGR--CENGRCVCNPGYAGEDCGVRSCPRGCSQRGRCKDG 324

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++GE C  R C   C E G+C +G C+C  G+ G  C+   CPR C G G+C 
Sbjct: 325  RCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRC- 383

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
               DG  EC C  G+ G DC     + C    D ++ G   CED  C   P    +  C 
Sbjct: 384  --EDG--ECICDTGYSGDDCGV---RSCPG--DCNQRG--RCEDGRCVCWPGYTGTD-CG 431

Query: 1178 SSPKPTD 1184
            S   P D
Sbjct: 432  SRACPRD 438



 Score =  136 bits (328), Expect = 2e-30
 Identities = 70/175 (40%), Positives = 89/175 (50%), Gaps = 16/175 (9%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPN CS  G C  G C C  G+  +DCS   CP  C  RG    G C C+PG+ G  C+ 
Sbjct: 590  CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 649

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSG----HGFCIEGTCVCK 993
            R   C   DC G G CV G C C  GY G+ CG+ + P   C G       C  G CVC 
Sbjct: 650  RM--CPA-DCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCV 706

Query: 994  KGWKGADCGTMDKDALQCLP-DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE 1047
            +G++G DC      A+Q  P DC G G  +    +C C   ++GEDC +EV ++E
Sbjct: 707  EGFRGPDC------AIQTCPGDCRGRG--ECHDGSCVCKDGYAGEDCGEEVPTIE 753



 Score =  120 bits (288), Expect = 1e-25
 Identities = 52/142 (36%), Positives = 72/142 (50%), Gaps = 4/142 (2%)

Query: 864  ISFVALVAEEMT-HNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYING 922
            I +   V+E+ +   CP+ C G+G C  G C C PG+ G  C+  +CP  C  RG  + G
Sbjct: 606  ICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQG 665

Query: 923  ECQCNPGWKGKECSLRHDECEV--PDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCS 980
             C C+ G+ G++C             C     C  G+C CV G++G  C    CP   C 
Sbjct: 666  VCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD-CR 724

Query: 981  GHGFCIEGTCVCKKGWKGADCG 1002
            G G C +G+CVCK G+ G DCG
Sbjct: 725  GRGECHDGSCVCKDGYAGEDCG 746



 Score =  113 bits (272), Expect = 9e-24
 Identities = 71/206 (34%), Positives = 92/206 (44%), Gaps = 20/206 (9%)

Query: 979  CSGHG-FCIEG-TCVCKKGWKGADCG--TMDKDALQCLPDCSGHGTFDVDTQ------TC 1028
            CS HG F +   TC C+ GW G  C   T  +      P  SG    D + Q       C
Sbjct: 143  CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C   ++G  C    C  +C   GRCV   C C AG+SG  CS R C   C++ G+C+ G
Sbjct: 203  VCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGG 262

Query: 1089 TCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
             C+C  G+ G  C +  CPR C+  G+C    +GR  C C  G+ G DC           
Sbjct: 263  RCVCDPGYTGDDCGMRSCPRGCSQRGRC---ENGR--CVCNPGYAGEDCGVRSCPRGCSQ 317

Query: 1149 RDNDKDGLVDCEDP----ECCQSPAC 1170
            R   KDG   C DP    E C + +C
Sbjct: 318  RGRCKDGRCVC-DPGYTGEDCGTRSC 342



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 51/148 (34%), Positives = 70/148 (47%), Gaps = 12/148 (8%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSK-----SVCPVLCSQRGEYINGECQCNPG 929
            T  CP  C G+G C+ G C C  G+GG+DC +     S CP  C  R     G+C C  G
Sbjct: 649  TRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEG 708

Query: 930  WKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGT 989
            ++G +C+++   C   DC G G C +G C C  GY G+ CGE     PT  G    +   
Sbjct: 709  FRGPDCAIQ--TCP-GDCRGRGECHDGSCVCKDGYAGEDCGE---EVPTIEGMRMHLLEE 762

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSG 1017
               +  W  A  G +D   +Q +P   G
Sbjct: 763  TTVRTEWTPAP-GPVDAYEIQFIPTTEG 789


>AL662828-1|CAI17414.1| 4222|Homo sapiens tenascin XB protein.
          Length = 4222

 Score =  245 bits (600), Expect = 2e-63
 Identities = 109/263 (41%), Positives = 142/263 (53%), Gaps = 16/263 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C+ +G C  G C C PG+ G DC    CP  C  RG   NG C CN G+ G++C 
Sbjct: 403  SCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCG 462

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C   DC G G C +G+C C  GY G+ CG   CP   C G G C++G CVC  G+
Sbjct: 463  VR--SCP-GDCRGRGRCESGRCMCWPGYTGRDCGTRACPGD-CRGRGRCVDGRCVCNPGF 518

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG+      +C  DC GHG    +   C C A +SGEDCS   C   C   G+C+ 
Sbjct: 519  TGEDCGSR-----RCPGDCRGHGL--CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SGE C VR C   C++HG C++G C+C  G+    C++  CP +C G G+C
Sbjct: 572  GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 631

Query: 1117 RVDNDGRWECKCFDGWDGPDCTT 1139
                +GR  C C  G+ GP C T
Sbjct: 632  ---EEGR--CLCDPGYTGPTCAT 649



 Score =  238 bits (582), Expect = 3e-61
 Identities = 119/308 (38%), Positives = 154/308 (50%), Gaps = 24/308 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP GCS +G C  G C C PG+ GDDC    CP  CSQRG   NG C CNPG+ G++C 
Sbjct: 248  SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYAGEDCG 307

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C +G+C C  GY G+ CG   CP   C   G C++G CVC  G+
Sbjct: 308  VR--SCP-RGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD-CGEGGRCVDGRCVCWPGY 363

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC T       C  DC G G  + D + C C   +SG+DC    C  +C   GRC  
Sbjct: 364  TGEDCSTRT-----CPRDCRGRGRCE-DGE-CICDTGYSGDDCGVRSCPGDCNQRGRCED 416

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C  R C   C   G+C+NG C+C +G++G  C +  CP  C G G+C
Sbjct: 417  GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476

Query: 1117 RVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                 GR  C C+ G+ G DC T   + C      D  G   C D  C  +P   + + C
Sbjct: 477  ---ESGR--CMCWPGYTGRDCGT---RAC----PGDCRGRGRCVDGRCVCNPGF-TGEDC 523

Query: 1177 VSSPKPTD 1184
             S   P D
Sbjct: 524  GSRRCPGD 531



 Score =  237 bits (581), Expect = 3e-61
 Identities = 108/263 (41%), Positives = 135/263 (51%), Gaps = 16/263 (6%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T +CP  C   G C+ G C C PG+ G+DCS   CP  C  RG   +GEC C+ G+ G +
Sbjct: 339  TRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDD 398

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C +R   C   DCN  G C +G+C C  GY G  CG   CP   C G G C  G CVC  
Sbjct: 399  CGVR--SCP-GDCNQRGRCEDGRCVCWPGYTGTDCGSRACPR-DCRGRGRCENGVCVCNA 454

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCG        C  DC G G    ++  C C   ++G DC    C  +C   GRC
Sbjct: 455  GYSGEDCGVR-----SCPGDCRGRGR--CESGRCMCWPGYTGRDCGTRACPGDCRGRGRC 507

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
            V   C C  G++GE C  R C   C  HG C++G C+C +G++G  C+   CP  C G G
Sbjct: 508  VDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRG 567

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
            QC    DGR  C C DG+ G DC
Sbjct: 568  QCL---DGR--CVCEDGYSGEDC 585



 Score =  237 bits (579), Expect = 6e-61
 Identities = 109/261 (41%), Positives = 137/261 (52%), Gaps = 16/261 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C+ G C C+ GF G DCS+  CP  CSQRG    G C C+PG+ G +C 
Sbjct: 217  SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG 276

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C NG+C C  GY G+ CG   CP   CS  G C +G CVC  G+
Sbjct: 277  MR--SCP-RGCSQRGRCENGRCVCNPGYAGEDCGVRSCPRG-CSQRGRCKDGRCVCDPGY 332

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCGT       C  DC G G   VD + C C   ++GEDCS   C  +C   GRC  
Sbjct: 333  TGEDCGTRS-----CPWDC-GEGGRCVDGR-CVCWPGYTGEDCSTRTCPRDCRGRGRCED 385

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SG+ C VR C   C + G+C++G C+C  G+ G  C    CPR C G G+C
Sbjct: 386  GECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC 445

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
                     C C  G+ G DC
Sbjct: 446  E-----NGVCVCNAGYSGEDC 461



 Score =  235 bits (576), Expect = 1e-60
 Identities = 120/310 (38%), Positives = 152/310 (49%), Gaps = 24/310 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C  G C C  G+ GDDC    CP  C+QRG   +G C C PG+ G +
Sbjct: 370  TRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTD 429

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C  R   C   DC G G C NG C C  GY G+ CG   CP   C G G C  G C+C  
Sbjct: 430  CGSR--ACP-RDCRGRGRCENGVCVCNAGYSGEDCGVRSCP-GDCRGRGRCESGRCMCWP 485

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCGT       C  DC G G   VD + C C+  ++GEDC    C  +C  HG C
Sbjct: 486  GYTGRDCGTR-----ACPGDCRGRGRC-VDGR-CVCNPGFTGEDCGSRRCPGDCRGHGLC 538

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
                C C AG+SGE CS R C   C   GQC +G C+C  G++G  C +  CP  C+ HG
Sbjct: 539  EDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHG 598

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQ 1174
             C+   DG   C C++G+   DC+    + C     ++  G   CE+  C   P   +  
Sbjct: 599  VCQ---DG--VCICWEGYVSEDCSI---RTC----PSNCHGRGRCEEGRCLCDPG-YTGP 645

Query: 1175 LCVSSPKPTD 1184
             C +   P D
Sbjct: 646  TCATRMCPAD 655



 Score =  231 bits (564), Expect = 4e-59
 Identities = 113/293 (38%), Positives = 138/293 (47%), Gaps = 28/293 (9%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C  G C C PG+ G DC    CP  C  RG  ++G C CNPG+ G++C 
Sbjct: 465  SCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG 524

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
             R   C   DC GHG C +G C C  GY G+ C    CP   C G G C++G CVC+ G+
Sbjct: 525  SRR--CP-GDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGY 580

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG       QC  DCS HG        C C   +  EDCS   C   C   GRC  
Sbjct: 581  SGEDCGVR-----QCPNDCSQHGV--CQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEE 633

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE-----GCPRSCA 1111
              C C  G++G  C+ R+C A C   G+C  G CLC  G+ G  C  E      CP  C 
Sbjct: 634  GRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCG 693

Query: 1112 GHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                CR       +C C +G+ GPDC     Q C      D  G  +C D  C
Sbjct: 694  PRELCRAG-----QCVCVEGFRGPDCAI---QTC----PGDCRGRGECHDGSC 734



 Score =  223 bits (545), Expect = 8e-57
 Identities = 103/260 (39%), Positives = 129/260 (49%), Gaps = 16/260 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C G+G C  G C C  G+ G+DC    CP  C  RG   +G C C PG+ G++C  
Sbjct: 435  CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC G G CV+G+C C  G+ G+ CG   CP   C GHG C +G CVC  G+ 
Sbjct: 495  R--ACP-GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGD-CRGHGLCEDGVCVCDAGYS 550

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC T       C   C G G   +D + C C   +SGEDC    C  +C  HG C   
Sbjct: 551  GEDCSTRS-----CPGGCRGRGQC-LDGR-CVCEDGYSGEDCGVRQCPNDCSQHGVCQDG 603

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+  E CS+R C + C   G+C+ G CLC  G+ G  C    CP  C G G+C 
Sbjct: 604  VCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC- 662

Query: 1118 VDNDGRWECKCFDGWDGPDC 1137
                 +  C C  G+ G DC
Sbjct: 663  ----VQGVCLCHVGYGGEDC 678



 Score =  218 bits (532), Expect = 3e-55
 Identities = 103/278 (37%), Positives = 133/278 (47%), Gaps = 16/278 (5%)

Query: 860  DPQEISFVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEY 919
            DP +           + +CP+ C+ +G C+ G C C PG+ G  C    CP  C  RG  
Sbjct: 169  DPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRC 228

Query: 920  INGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTC 979
            + G C C  G+ G +CS R   C    C+  G C  G+C C  GY G  CG   CP   C
Sbjct: 229  VQGVCVCRAGFSGPDCSQR--SCP-RGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPR-GC 284

Query: 980  SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
            S  G C  G CVC  G+ G DCG        C   CS  G        C C   ++GEDC
Sbjct: 285  SQRGRCENGRCVCNPGYAGEDCGVR-----SCPRGCSQRGR--CKDGRCVCDPGYTGEDC 337

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR 1099
                C  +CG  GRCV   C C  G++GE CS R C   C   G+C++G C+C +G++G 
Sbjct: 338  GTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGD 397

Query: 1100 HCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +  CP  C   G+C    DGR  C C+ G+ G DC
Sbjct: 398  DCGVRSCPGDCNQRGRC---EDGR--CVCWPGYTGTDC 430



 Score =  215 bits (524), Expect = 3e-54
 Identities = 99/268 (36%), Positives = 132/268 (49%), Gaps = 21/268 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C+ G C C PGF G+DC    CP  C   G   +G C C+ G+ G++
Sbjct: 494  TRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGED 553

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            CS R   C    C G G C++G+C C  GY G+ CG   CP+  CS HG C +G C+C +
Sbjct: 554  CSTR--SCP-GGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWE 609

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+   DC         C  +C G G    +   C C   ++G  C+  +C  +C   GRC
Sbjct: 610  GYVSEDCSIRT-----CPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662

Query: 1055 VGESCSCAAGWSGEFCS-----VRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS 1109
            V   C C  G+ GE C         C   C     C+ G C+CV G+ G  C ++ CP  
Sbjct: 663  VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD 722

Query: 1110 CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C G G+C   +DG   C C DG+ G DC
Sbjct: 723  CRGRGEC---HDG--SCVCKDGYAGEDC 745



 Score =  190 bits (462), Expect = 9e-47
 Identities = 108/307 (35%), Positives = 134/307 (43%), Gaps = 39/307 (12%)

Query: 893  CQCQPGFGGDDCS---------------KSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C C+PG+GG  CS                  CP  C+ +G  + G C C PG+ G  C  
Sbjct: 156  CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG- 214

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C   DC G G CV G C C  G+ G  C +  CP   CS  G C  G CVC  G+ 
Sbjct: 215  -WPSCP-GDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPR-GCSQRGRCEGGRCVCDPGYT 271

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DCG        C   CS  G    +   C C+  ++GEDC    C   C   GRC   
Sbjct: 272  GDDCGMR-----SCPRGCSQRGR--CENGRCVCNPGYAGEDCGVRSCPRGCSQRGRCKDG 324

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++GE C  R C   C E G+C +G C+C  G+ G  C+   CPR C G G+C 
Sbjct: 325  RCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRC- 383

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
               DG  EC C  G+ G DC     + C    D ++ G   CED  C   P    +  C 
Sbjct: 384  --EDG--ECICDTGYSGDDCGV---RSCPG--DCNQRG--RCEDGRCVCWPGYTGTD-CG 431

Query: 1178 SSPKPTD 1184
            S   P D
Sbjct: 432  SRACPRD 438



 Score =  136 bits (328), Expect = 2e-30
 Identities = 70/175 (40%), Positives = 89/175 (50%), Gaps = 16/175 (9%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPN CS  G C  G C C  G+  +DCS   CP  C  RG    G C C+PG+ G  C+ 
Sbjct: 590  CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 649

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSG----HGFCIEGTCVCK 993
            R   C   DC G G CV G C C  GY G+ CG+ + P   C G       C  G CVC 
Sbjct: 650  RM--CPA-DCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCV 706

Query: 994  KGWKGADCGTMDKDALQCLP-DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE 1047
            +G++G DC      A+Q  P DC G G  +    +C C   ++GEDC +EV ++E
Sbjct: 707  EGFRGPDC------AIQTCPGDCRGRG--ECHDGSCVCKDGYAGEDCGEEVPTIE 753



 Score =  120 bits (288), Expect = 1e-25
 Identities = 52/142 (36%), Positives = 72/142 (50%), Gaps = 4/142 (2%)

Query: 864  ISFVALVAEEMT-HNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYING 922
            I +   V+E+ +   CP+ C G+G C  G C C PG+ G  C+  +CP  C  RG  + G
Sbjct: 606  ICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQG 665

Query: 923  ECQCNPGWKGKECSLRHDECEV--PDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCS 980
             C C+ G+ G++C             C     C  G+C CV G++G  C    CP   C 
Sbjct: 666  VCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD-CR 724

Query: 981  GHGFCIEGTCVCKKGWKGADCG 1002
            G G C +G+CVCK G+ G DCG
Sbjct: 725  GRGECHDGSCVCKDGYAGEDCG 746



 Score =  113 bits (272), Expect = 9e-24
 Identities = 71/206 (34%), Positives = 92/206 (44%), Gaps = 20/206 (9%)

Query: 979  CSGHG-FCIEG-TCVCKKGWKGADCG--TMDKDALQCLPDCSGHGTFDVDTQ------TC 1028
            CS HG F +   TC C+ GW G  C   T  +      P  SG    D + Q       C
Sbjct: 143  CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C   ++G  C    C  +C   GRCV   C C AG+SG  CS R C   C++ G+C+ G
Sbjct: 203  VCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGG 262

Query: 1089 TCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
             C+C  G+ G  C +  CPR C+  G+C    +GR  C C  G+ G DC           
Sbjct: 263  RCVCDPGYTGDDCGMRSCPRGCSQRGRC---ENGR--CVCNPGYAGEDCGVRSCPRGCSQ 317

Query: 1149 RDNDKDGLVDCEDP----ECCQSPAC 1170
            R   KDG   C DP    E C + +C
Sbjct: 318  RGRCKDGRCVC-DPGYTGEDCGTRSC 342



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 51/148 (34%), Positives = 70/148 (47%), Gaps = 12/148 (8%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSK-----SVCPVLCSQRGEYINGECQCNPG 929
            T  CP  C G+G C+ G C C  G+GG+DC +     S CP  C  R     G+C C  G
Sbjct: 649  TRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEG 708

Query: 930  WKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGT 989
            ++G +C+++   C   DC G G C +G C C  GY G+ CGE     PT  G    +   
Sbjct: 709  FRGPDCAIQ--TCP-GDCRGRGECHDGSCVCKDGYAGEDCGE---EVPTIEGMRMHLLEE 762

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSG 1017
               +  W  A  G +D   +Q +P   G
Sbjct: 763  TTVRTEWTPAP-GPVDAYEIQFIPTTEG 789


>AL645922-1|CAI41718.1| 4222|Homo sapiens tenascin XB protein.
          Length = 4222

 Score =  245 bits (600), Expect = 2e-63
 Identities = 109/263 (41%), Positives = 142/263 (53%), Gaps = 16/263 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C+ +G C  G C C PG+ G DC    CP  C  RG   NG C CN G+ G++C 
Sbjct: 403  SCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCG 462

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C   DC G G C +G+C C  GY G+ CG   CP   C G G C++G CVC  G+
Sbjct: 463  VR--SCP-GDCRGRGRCESGRCMCWPGYTGRDCGTRACPGD-CRGRGRCVDGRCVCNPGF 518

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG+      +C  DC GHG    +   C C A +SGEDCS   C   C   G+C+ 
Sbjct: 519  TGEDCGSR-----RCPGDCRGHGL--CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SGE C VR C   C++HG C++G C+C  G+    C++  CP +C G G+C
Sbjct: 572  GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 631

Query: 1117 RVDNDGRWECKCFDGWDGPDCTT 1139
                +GR  C C  G+ GP C T
Sbjct: 632  ---EEGR--CLCDPGYTGPTCAT 649



 Score =  238 bits (582), Expect = 3e-61
 Identities = 119/308 (38%), Positives = 154/308 (50%), Gaps = 24/308 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP GCS +G C  G C C PG+ GDDC    CP  CSQRG   NG C CNPG+ G++C 
Sbjct: 248  SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C +G+C C  GY G+ CG   CP   C   G C++G CVC  G+
Sbjct: 308  VR--SCP-RGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD-CGEGGRCVDGRCVCWPGY 363

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC T       C  DC G G  + D + C C   +SG+DC    C  +C   GRC  
Sbjct: 364  TGEDCSTRT-----CPRDCRGRGRCE-DGE-CICDTGYSGDDCGVRSCPGDCNQRGRCED 416

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C  R C   C   G+C+NG C+C +G++G  C +  CP  C G G+C
Sbjct: 417  GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476

Query: 1117 RVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                 GR  C C+ G+ G DC T   + C      D  G   C D  C  +P   + + C
Sbjct: 477  ---ESGR--CMCWPGYTGRDCGT---RAC----PGDCRGRGRCVDGRCVCNPGF-TGEDC 523

Query: 1177 VSSPKPTD 1184
             S   P D
Sbjct: 524  GSRRCPGD 531



 Score =  237 bits (581), Expect = 3e-61
 Identities = 108/263 (41%), Positives = 135/263 (51%), Gaps = 16/263 (6%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T +CP  C   G C+ G C C PG+ G+DCS   CP  C  RG   +GEC C+ G+ G +
Sbjct: 339  TRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDD 398

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C +R   C   DCN  G C +G+C C  GY G  CG   CP   C G G C  G CVC  
Sbjct: 399  CGVR--SCP-GDCNQRGRCEDGRCVCWPGYTGTDCGSRACPR-DCRGRGRCENGVCVCNA 454

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCG        C  DC G G    ++  C C   ++G DC    C  +C   GRC
Sbjct: 455  GYSGEDCGVR-----SCPGDCRGRGR--CESGRCMCWPGYTGRDCGTRACPGDCRGRGRC 507

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
            V   C C  G++GE C  R C   C  HG C++G C+C +G++G  C+   CP  C G G
Sbjct: 508  VDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRG 567

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
            QC    DGR  C C DG+ G DC
Sbjct: 568  QCL---DGR--CVCEDGYSGEDC 585



 Score =  237 bits (579), Expect = 6e-61
 Identities = 109/261 (41%), Positives = 137/261 (52%), Gaps = 16/261 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C+ G C C+ GF G DCS+  CP  CSQRG    G C C+PG+ G +C 
Sbjct: 217  SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG 276

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C NG+C C  GY G+ CG   CP   CS  G C +G CVC  G+
Sbjct: 277  MR--SCP-RGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRG-CSQRGRCKDGRCVCDPGY 332

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCGT       C  DC G G   VD + C C   ++GEDCS   C  +C   GRC  
Sbjct: 333  TGEDCGTRS-----CPWDC-GEGGRCVDGR-CVCWPGYTGEDCSTRTCPRDCRGRGRCED 385

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SG+ C VR C   C + G+C++G C+C  G+ G  C    CPR C G G+C
Sbjct: 386  GECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC 445

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
                     C C  G+ G DC
Sbjct: 446  E-----NGVCVCNAGYSGEDC 461



 Score =  235 bits (576), Expect = 1e-60
 Identities = 120/310 (38%), Positives = 152/310 (49%), Gaps = 24/310 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C  G C C  G+ GDDC    CP  C+QRG   +G C C PG+ G +
Sbjct: 370  TRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTD 429

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C  R   C   DC G G C NG C C  GY G+ CG   CP   C G G C  G C+C  
Sbjct: 430  CGSR--ACP-RDCRGRGRCENGVCVCNAGYSGEDCGVRSCP-GDCRGRGRCESGRCMCWP 485

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCGT       C  DC G G   VD + C C+  ++GEDC    C  +C  HG C
Sbjct: 486  GYTGRDCGTR-----ACPGDCRGRGRC-VDGR-CVCNPGFTGEDCGSRRCPGDCRGHGLC 538

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
                C C AG+SGE CS R C   C   GQC +G C+C  G++G  C +  CP  C+ HG
Sbjct: 539  EDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHG 598

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQ 1174
             C+   DG   C C++G+   DC+    + C     ++  G   CE+  C   P   +  
Sbjct: 599  VCQ---DG--VCICWEGYVSEDCSI---RTC----PSNCHGRGRCEEGRCLCDPG-YTGP 645

Query: 1175 LCVSSPKPTD 1184
             C +   P D
Sbjct: 646  TCATRMCPAD 655



 Score =  231 bits (564), Expect = 4e-59
 Identities = 113/293 (38%), Positives = 138/293 (47%), Gaps = 28/293 (9%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C  G C C PG+ G DC    CP  C  RG  ++G C CNPG+ G++C 
Sbjct: 465  SCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG 524

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
             R   C   DC GHG C +G C C  GY G+ C    CP   C G G C++G CVC+ G+
Sbjct: 525  SRR--CP-GDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGY 580

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG       QC  DCS HG        C C   +  EDCS   C   C   GRC  
Sbjct: 581  SGEDCGVR-----QCPNDCSQHGV--CQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEE 633

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE-----GCPRSCA 1111
              C C  G++G  C+ R+C A C   G+C  G CLC  G+ G  C  E      CP  C 
Sbjct: 634  GRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCG 693

Query: 1112 GHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                CR       +C C +G+ GPDC     Q C      D  G  +C D  C
Sbjct: 694  PRELCRAG-----QCVCVEGFRGPDCAI---QTC----PGDCRGRGECHDGSC 734



 Score =  223 bits (545), Expect = 8e-57
 Identities = 103/260 (39%), Positives = 129/260 (49%), Gaps = 16/260 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C G+G C  G C C  G+ G+DC    CP  C  RG   +G C C PG+ G++C  
Sbjct: 435  CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC G G CV+G+C C  G+ G+ CG   CP   C GHG C +G CVC  G+ 
Sbjct: 495  R--ACP-GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGD-CRGHGLCEDGVCVCDAGYS 550

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC T       C   C G G   +D + C C   +SGEDC    C  +C  HG C   
Sbjct: 551  GEDCSTRS-----CPGGCRGRGQC-LDGR-CVCEDGYSGEDCGVRQCPNDCSQHGVCQDG 603

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+  E CS+R C + C   G+C+ G CLC  G+ G  C    CP  C G G+C 
Sbjct: 604  VCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC- 662

Query: 1118 VDNDGRWECKCFDGWDGPDC 1137
                 +  C C  G+ G DC
Sbjct: 663  ----VQGVCLCHVGYGGEDC 678



 Score =  218 bits (532), Expect = 3e-55
 Identities = 103/278 (37%), Positives = 133/278 (47%), Gaps = 16/278 (5%)

Query: 860  DPQEISFVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEY 919
            DP +           + +CP+ C+ +G C+ G C C PG+ G  C    CP  C  RG  
Sbjct: 169  DPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRC 228

Query: 920  INGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTC 979
            + G C C  G+ G +CS R   C    C+  G C  G+C C  GY G  CG   CP   C
Sbjct: 229  VQGVCVCRAGFSGPDCSQR--SCP-RGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPR-GC 284

Query: 980  SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
            S  G C  G CVC  G+ G DCG        C   CS  G        C C   ++GEDC
Sbjct: 285  SQRGRCENGRCVCNPGYTGEDCGVR-----SCPRGCSQRGR--CKDGRCVCDPGYTGEDC 337

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR 1099
                C  +CG  GRCV   C C  G++GE CS R C   C   G+C++G C+C +G++G 
Sbjct: 338  GTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGD 397

Query: 1100 HCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +  CP  C   G+C    DGR  C C+ G+ G DC
Sbjct: 398  DCGVRSCPGDCNQRGRC---EDGR--CVCWPGYTGTDC 430



 Score =  215 bits (524), Expect = 3e-54
 Identities = 99/268 (36%), Positives = 132/268 (49%), Gaps = 21/268 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C+ G C C PGF G+DC    CP  C   G   +G C C+ G+ G++
Sbjct: 494  TRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGED 553

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            CS R   C    C G G C++G+C C  GY G+ CG   CP+  CS HG C +G C+C +
Sbjct: 554  CSTR--SCP-GGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWE 609

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+   DC         C  +C G G    +   C C   ++G  C+  +C  +C   GRC
Sbjct: 610  GYVSEDCSIRT-----CPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662

Query: 1055 VGESCSCAAGWSGEFCS-----VRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS 1109
            V   C C  G+ GE C         C   C     C+ G C+CV G+ G  C ++ CP  
Sbjct: 663  VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD 722

Query: 1110 CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C G G+C   +DG   C C DG+ G DC
Sbjct: 723  CRGRGEC---HDG--SCVCKDGYAGEDC 745



 Score =  190 bits (462), Expect = 9e-47
 Identities = 108/307 (35%), Positives = 134/307 (43%), Gaps = 39/307 (12%)

Query: 893  CQCQPGFGGDDCS---------------KSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C C+PG+GG  CS                  CP  C+ +G  + G C C PG+ G  C  
Sbjct: 156  CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG- 214

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C   DC G G CV G C C  G+ G  C +  CP   CS  G C  G CVC  G+ 
Sbjct: 215  -WPSCP-GDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPR-GCSQRGRCEGGRCVCDPGYT 271

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DCG        C   CS  G    +   C C+  ++GEDC    C   C   GRC   
Sbjct: 272  GDDCGMR-----SCPRGCSQRGR--CENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDG 324

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++GE C  R C   C E G+C +G C+C  G+ G  C+   CPR C G G+C 
Sbjct: 325  RCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRC- 383

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
               DG  EC C  G+ G DC     + C    D ++ G   CED  C   P    +  C 
Sbjct: 384  --EDG--ECICDTGYSGDDCGV---RSCPG--DCNQRG--RCEDGRCVCWPGYTGTD-CG 431

Query: 1178 SSPKPTD 1184
            S   P D
Sbjct: 432  SRACPRD 438



 Score =  136 bits (328), Expect = 2e-30
 Identities = 70/175 (40%), Positives = 89/175 (50%), Gaps = 16/175 (9%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPN CS  G C  G C C  G+  +DCS   CP  C  RG    G C C+PG+ G  C+ 
Sbjct: 590  CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 649

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSG----HGFCIEGTCVCK 993
            R   C   DC G G CV G C C  GY G+ CG+ + P   C G       C  G CVC 
Sbjct: 650  RM--CPA-DCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCV 706

Query: 994  KGWKGADCGTMDKDALQCLP-DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE 1047
            +G++G DC      A+Q  P DC G G  +    +C C   ++GEDC +EV ++E
Sbjct: 707  EGFRGPDC------AIQTCPGDCRGRG--ECHDGSCVCKDGYAGEDCGEEVPTIE 753



 Score =  120 bits (288), Expect = 1e-25
 Identities = 52/142 (36%), Positives = 72/142 (50%), Gaps = 4/142 (2%)

Query: 864  ISFVALVAEEMT-HNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYING 922
            I +   V+E+ +   CP+ C G+G C  G C C PG+ G  C+  +CP  C  RG  + G
Sbjct: 606  ICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQG 665

Query: 923  ECQCNPGWKGKECSLRHDECEV--PDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCS 980
             C C+ G+ G++C             C     C  G+C CV G++G  C    CP   C 
Sbjct: 666  VCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD-CR 724

Query: 981  GHGFCIEGTCVCKKGWKGADCG 1002
            G G C +G+CVCK G+ G DCG
Sbjct: 725  GRGECHDGSCVCKDGYAGEDCG 746



 Score =  113 bits (273), Expect = 7e-24
 Identities = 71/206 (34%), Positives = 92/206 (44%), Gaps = 20/206 (9%)

Query: 979  CSGHG-FCIEG-TCVCKKGWKGADCG--TMDKDALQCLPDCSGHGTFDVDTQ------TC 1028
            CS HG F +   TC C+ GW G  C   T  +      P  SG    D + Q       C
Sbjct: 143  CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 202

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C   ++G  C    C  +C   GRCV   C C AG+SG  CS R C   C++ G+C+ G
Sbjct: 203  VCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGG 262

Query: 1089 TCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
             C+C  G+ G  C +  CPR C+  G+C    +GR  C C  G+ G DC           
Sbjct: 263  RCVCDPGYTGDDCGMRSCPRGCSQRGRC---ENGR--CVCNPGYTGEDCGVRSCPRGCSQ 317

Query: 1149 RDNDKDGLVDCEDP----ECCQSPAC 1170
            R   KDG   C DP    E C + +C
Sbjct: 318  RGRCKDGRCVC-DPGYTGEDCGTRSC 342



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 51/148 (34%), Positives = 70/148 (47%), Gaps = 12/148 (8%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSK-----SVCPVLCSQRGEYINGECQCNPG 929
            T  CP  C G+G C+ G C C  G+GG+DC +     S CP  C  R     G+C C  G
Sbjct: 649  TRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEG 708

Query: 930  WKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGT 989
            ++G +C+++   C   DC G G C +G C C  GY G+ CGE     PT  G    +   
Sbjct: 709  FRGPDCAIQ--TCP-GDCRGRGECHDGSCVCKDGYAGEDCGE---EVPTIEGMRMHLLEE 762

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSG 1017
               +  W  A  G +D   +Q +P   G
Sbjct: 763  TTVRTEWTPAP-GPVDAYEIQFIPTTEG 789


>AL049547-2|CAB89296.1| 4288|Homo sapiens dJ34F7.1.1 (tenascin XB
            (isoform 1)) protein.
          Length = 4288

 Score =  245 bits (600), Expect = 2e-63
 Identities = 109/263 (41%), Positives = 142/263 (53%), Gaps = 16/263 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C+ +G C  G C C PG+ G DC    CP  C  RG   NG C CN G+ G++C 
Sbjct: 402  SCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCG 461

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C   DC G G C +G+C C  GY G+ CG   CP   C G G C++G CVC  G+
Sbjct: 462  VR--SCP-GDCRGRGRCESGRCMCWPGYTGRDCGTRACPGD-CRGRGRCVDGRCVCNPGF 517

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG+      +C  DC GHG    +   C C A +SGEDCS   C   C   G+C+ 
Sbjct: 518  TGEDCGSR-----RCPGDCRGHGL--CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 570

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SGE C VR C   C++HG C++G C+C  G+    C++  CP +C G G+C
Sbjct: 571  GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 630

Query: 1117 RVDNDGRWECKCFDGWDGPDCTT 1139
                +GR  C C  G+ GP C T
Sbjct: 631  ---EEGR--CLCDPGYTGPTCAT 648



 Score =  238 bits (582), Expect = 3e-61
 Identities = 119/308 (38%), Positives = 154/308 (50%), Gaps = 24/308 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP GCS +G C  G C C PG+ GDDC    CP  CSQRG   NG C CNPG+ G++C 
Sbjct: 247  SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYAGEDCG 306

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C +G+C C  GY G+ CG   CP   C   G C++G CVC  G+
Sbjct: 307  VR--SCP-RGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD-CGEGGRCVDGRCVCWPGY 362

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC T       C  DC G G  + D + C C   +SG+DC    C  +C   GRC  
Sbjct: 363  TGEDCSTRT-----CPRDCRGRGRCE-DGE-CICDTGYSGDDCGVRSCPGDCNQRGRCED 415

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C  R C   C   G+C+NG C+C +G++G  C +  CP  C G G+C
Sbjct: 416  GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 475

Query: 1117 RVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                 GR  C C+ G+ G DC T   + C      D  G   C D  C  +P   + + C
Sbjct: 476  ---ESGR--CMCWPGYTGRDCGT---RAC----PGDCRGRGRCVDGRCVCNPGF-TGEDC 522

Query: 1177 VSSPKPTD 1184
             S   P D
Sbjct: 523  GSRRCPGD 530



 Score =  237 bits (581), Expect = 3e-61
 Identities = 108/263 (41%), Positives = 135/263 (51%), Gaps = 16/263 (6%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T +CP  C   G C+ G C C PG+ G+DCS   CP  C  RG   +GEC C+ G+ G +
Sbjct: 338  TRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDD 397

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C +R   C   DCN  G C +G+C C  GY G  CG   CP   C G G C  G CVC  
Sbjct: 398  CGVR--SCP-GDCNQRGRCEDGRCVCWPGYTGTDCGSRACPR-DCRGRGRCENGVCVCNA 453

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCG        C  DC G G    ++  C C   ++G DC    C  +C   GRC
Sbjct: 454  GYSGEDCGVR-----SCPGDCRGRGR--CESGRCMCWPGYTGRDCGTRACPGDCRGRGRC 506

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
            V   C C  G++GE C  R C   C  HG C++G C+C +G++G  C+   CP  C G G
Sbjct: 507  VDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRG 566

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
            QC    DGR  C C DG+ G DC
Sbjct: 567  QCL---DGR--CVCEDGYSGEDC 584



 Score =  237 bits (579), Expect = 6e-61
 Identities = 109/261 (41%), Positives = 137/261 (52%), Gaps = 16/261 (6%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C+ G C C+ GF G DCS+  CP  CSQRG    G C C+PG+ G +C 
Sbjct: 216  SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG 275

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
            +R   C    C+  G C NG+C C  GY G+ CG   CP   CS  G C +G CVC  G+
Sbjct: 276  MR--SCP-RGCSQRGRCENGRCVCNPGYAGEDCGVRSCPRG-CSQRGRCKDGRCVCDPGY 331

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCGT       C  DC G G   VD + C C   ++GEDCS   C  +C   GRC  
Sbjct: 332  TGEDCGTRS-----CPWDC-GEGGRCVDGR-CVCWPGYTGEDCSTRTCPRDCRGRGRCED 384

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+SG+ C VR C   C + G+C++G C+C  G+ G  C    CPR C G G+C
Sbjct: 385  GECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC 444

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
                     C C  G+ G DC
Sbjct: 445  E-----NGVCVCNAGYSGEDC 460



 Score =  235 bits (576), Expect = 1e-60
 Identities = 120/310 (38%), Positives = 152/310 (49%), Gaps = 24/310 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C  G C C  G+ GDDC    CP  C+QRG   +G C C PG+ G +
Sbjct: 369  TRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTD 428

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C  R   C   DC G G C NG C C  GY G+ CG   CP   C G G C  G C+C  
Sbjct: 429  CGSR--ACP-RDCRGRGRCENGVCVCNAGYSGEDCGVRSCP-GDCRGRGRCESGRCMCWP 484

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+ G DCGT       C  DC G G   VD + C C+  ++GEDC    C  +C  HG C
Sbjct: 485  GYTGRDCGTR-----ACPGDCRGRGRC-VDGR-CVCNPGFTGEDCGSRRCPGDCRGHGLC 537

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
                C C AG+SGE CS R C   C   GQC +G C+C  G++G  C +  CP  C+ HG
Sbjct: 538  EDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHG 597

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQ 1174
             C+   DG   C C++G+   DC+    + C     ++  G   CE+  C   P   +  
Sbjct: 598  VCQ---DG--VCICWEGYVSEDCSI---RTC----PSNCHGRGRCEEGRCLCDPG-YTGP 644

Query: 1175 LCVSSPKPTD 1184
             C +   P D
Sbjct: 645  TCATRMCPAD 654



 Score =  231 bits (564), Expect = 4e-59
 Identities = 113/293 (38%), Positives = 138/293 (47%), Gaps = 28/293 (9%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CP  C G+G C  G C C PG+ G DC    CP  C  RG  ++G C CNPG+ G++C 
Sbjct: 464  SCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCG 523

Query: 937  LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
             R   C   DC GHG C +G C C  GY G+ C    CP   C G G C++G CVC+ G+
Sbjct: 524  SRR--CP-GDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCEDGY 579

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DCG       QC  DCS HG        C C   +  EDCS   C   C   GRC  
Sbjct: 580  SGEDCGVR-----QCPNDCSQHGV--CQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEE 632

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE-----GCPRSCA 1111
              C C  G++G  C+ R+C A C   G+C  G CLC  G+ G  C  E      CP  C 
Sbjct: 633  GRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCG 692

Query: 1112 GHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                CR       +C C +G+ GPDC     Q C      D  G  +C D  C
Sbjct: 693  PRELCRAG-----QCVCVEGFRGPDCAI---QTC----PGDCRGRGECHDGSC 733



 Score =  223 bits (545), Expect = 8e-57
 Identities = 103/260 (39%), Positives = 129/260 (49%), Gaps = 16/260 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C G+G C  G C C  G+ G+DC    CP  C  RG   +G C C PG+ G++C  
Sbjct: 434  CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 493

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC G G CV+G+C C  G+ G+ CG   CP   C GHG C +G CVC  G+ 
Sbjct: 494  R--ACP-GDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGD-CRGHGLCEDGVCVCDAGYS 549

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC T       C   C G G   +D + C C   +SGEDC    C  +C  HG C   
Sbjct: 550  GEDCSTRS-----CPGGCRGRGQC-LDGR-CVCEDGYSGEDCGVRQCPNDCSQHGVCQDG 602

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+  E CS+R C + C   G+C+ G CLC  G+ G  C    CP  C G G+C 
Sbjct: 603  VCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC- 661

Query: 1118 VDNDGRWECKCFDGWDGPDC 1137
                 +  C C  G+ G DC
Sbjct: 662  ----VQGVCLCHVGYGGEDC 677



 Score =  218 bits (532), Expect = 3e-55
 Identities = 103/278 (37%), Positives = 133/278 (47%), Gaps = 16/278 (5%)

Query: 860  DPQEISFVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEY 919
            DP +           + +CP+ C+ +G C+ G C C PG+ G  C    CP  C  RG  
Sbjct: 168  DPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRC 227

Query: 920  INGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTC 979
            + G C C  G+ G +CS R   C    C+  G C  G+C C  GY G  CG   CP   C
Sbjct: 228  VQGVCVCRAGFSGPDCSQR--SCP-RGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPR-GC 283

Query: 980  SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
            S  G C  G CVC  G+ G DCG        C   CS  G        C C   ++GEDC
Sbjct: 284  SQRGRCENGRCVCNPGYAGEDCGVR-----SCPRGCSQRGR--CKDGRCVCDPGYTGEDC 336

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR 1099
                C  +CG  GRCV   C C  G++GE CS R C   C   G+C++G C+C +G++G 
Sbjct: 337  GTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGD 396

Query: 1100 HCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +  CP  C   G+C    DGR  C C+ G+ G DC
Sbjct: 397  DCGVRSCPGDCNQRGRC---EDGR--CVCWPGYTGTDC 429



 Score =  215 bits (524), Expect = 3e-54
 Identities = 99/268 (36%), Positives = 132/268 (49%), Gaps = 21/268 (7%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            T  CP  C G+G C+ G C C PGF G+DC    CP  C   G   +G C C+ G+ G++
Sbjct: 493  TRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGED 552

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            CS R   C    C G G C++G+C C  GY G+ CG   CP+  CS HG C +G C+C +
Sbjct: 553  CSTR--SCP-GGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPND-CSQHGVCQDGVCICWE 608

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC 1054
            G+   DC         C  +C G G    +   C C   ++G  C+  +C  +C   GRC
Sbjct: 609  GYVSEDCSIRT-----CPSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 661

Query: 1055 VGESCSCAAGWSGEFCS-----VRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS 1109
            V   C C  G+ GE C         C   C     C+ G C+CV G+ G  C ++ CP  
Sbjct: 662  VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD 721

Query: 1110 CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C G G+C   +DG   C C DG+ G DC
Sbjct: 722  CRGRGEC---HDG--SCVCKDGYAGEDC 744



 Score =  190 bits (462), Expect = 9e-47
 Identities = 108/307 (35%), Positives = 134/307 (43%), Gaps = 39/307 (12%)

Query: 893  CQCQPGFGGDDCS---------------KSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C C+PG+GG  CS                  CP  C+ +G  + G C C PG+ G  C  
Sbjct: 155  CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCG- 213

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C   DC G G CV G C C  G+ G  C +  CP   CS  G C  G CVC  G+ 
Sbjct: 214  -WPSCP-GDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPR-GCSQRGRCEGGRCVCDPGYT 270

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DCG        C   CS  G    +   C C+  ++GEDC    C   C   GRC   
Sbjct: 271  GDDCGMR-----SCPRGCSQRGR--CENGRCVCNPGYAGEDCGVRSCPRGCSQRGRCKDG 323

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++GE C  R C   C E G+C +G C+C  G+ G  C+   CPR C G G+C 
Sbjct: 324  RCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRC- 382

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
               DG  EC C  G+ G DC     + C    D ++ G   CED  C   P    +  C 
Sbjct: 383  --EDG--ECICDTGYSGDDCGV---RSCPG--DCNQRG--RCEDGRCVCWPGYTGTD-CG 430

Query: 1178 SSPKPTD 1184
            S   P D
Sbjct: 431  SRACPRD 437



 Score =  188 bits (459), Expect = 2e-46
 Identities = 88/246 (35%), Positives = 117/246 (47%), Gaps = 16/246 (6%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            +  CP  C G G C  G C C  G+ G+DCS   CP  C  RG+ ++G C C  G+ G++
Sbjct: 524  SRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGED 583

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKK 994
            C +R  +C   DC+ HG C +G C C  GY  + C    CP   C G G C EG C+C  
Sbjct: 584  CGVR--QCP-NDCSQHGVCQDGVCICWEGYVSEDCSIRTCPS-NCHGRGRCEEGRCLCDP 639

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE-----VCSLECG 1049
            G+ G  C T       C  DC G G        C CH  + GEDC +E      C   CG
Sbjct: 640  GYTGPTCATR-----MCPADCRGRGR--CVQGVCLCHVGYGGEDCGQEEPPASACPGGCG 692

Query: 1050 PHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS 1109
            P   C    C C  G+ G  C+++ C   C   G+C +G+C+C  G+ G  C     P S
Sbjct: 693  PRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEARVPSS 752

Query: 1110 CAGHGQ 1115
             + + Q
Sbjct: 753  ASAYDQ 758



 Score =  113 bits (272), Expect = 9e-24
 Identities = 71/206 (34%), Positives = 92/206 (44%), Gaps = 20/206 (9%)

Query: 979  CSGHG-FCIEG-TCVCKKGWKGADCG--TMDKDALQCLPDCSGHGTFDVDTQ------TC 1028
            CS HG F +   TC C+ GW G  C   T  +      P  SG    D + Q       C
Sbjct: 142  CSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRC 201

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C   ++G  C    C  +C   GRCV   C C AG+SG  CS R C   C++ G+C+ G
Sbjct: 202  VCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGG 261

Query: 1089 TCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
             C+C  G+ G  C +  CPR C+  G+C    +GR  C C  G+ G DC           
Sbjct: 262  RCVCDPGYTGDDCGMRSCPRGCSQRGRC---ENGR--CVCNPGYAGEDCGVRSCPRGCSQ 316

Query: 1149 RDNDKDGLVDCEDP----ECCQSPAC 1170
            R   KDG   C DP    E C + +C
Sbjct: 317  RGRCKDGRCVC-DPGYTGEDCGTRSC 341


>X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein.
          Length = 2199

 Score =  230 bits (562), Expect = 7e-59
 Identities = 103/261 (39%), Positives = 139/261 (53%), Gaps = 18/261 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP+ C  +G C  G C C  GF G DCS+  CP  C  RG  ++G C+C+ G+ G +C  
Sbjct: 345  CPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCG- 403

Query: 938  RHDECEVPD-CNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
               E + P+ C+GHG CVNG+C C  GY G+ C ++ CP+  C   G C+EG CVC++G+
Sbjct: 404  ---ELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPND-CHSRGRCVEGKCVCEQGF 459

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
            KG DC  M      C  DC  HG        C C   ++GEDC    C  +C   G CV 
Sbjct: 460  KGYDCSDMS-----CPNDCHQHGR--CVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD 512

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C+   C   C   G+C NG C+C  G+ G+ C  + CP  C G G+C
Sbjct: 513  GQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRC 572

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
             VD     +C C +G+ G DC
Sbjct: 573  -VDG----QCICHEGFTGLDC 588



 Score =  228 bits (557), Expect = 3e-58
 Identities = 114/287 (39%), Positives = 144/287 (50%), Gaps = 23/287 (8%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C N C  +G C+   C C  GF G+DCS+ +CP  C  RG  ING C C  G+ G++C  
Sbjct: 283  CLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCG- 341

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C    C+  G C  G+C C  G+ G  C E  CP   C   G C++G C C  G+ 
Sbjct: 342  -KPTCPHA-CHTQGRCEEGQCVCDEGFAGVDCSEKRCP-ADCHNRGRCVDGRCECDDGFT 398

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            GADCG      L+C   CSGHG   V+ Q C C   ++GEDCS+  C  +C   GRCV  
Sbjct: 399  GADCGE-----LKCPNGCSGHGRC-VNGQ-CVCDEGYTGEDCSQLRCPNDCHSRGRCVEG 451

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+ G  CS   C   C +HG+C NG C+C  G+ G  C    CPR C+  G C 
Sbjct: 452  KCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLC- 510

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
            VD     +C C DG+ GPDC  L       S  ND  G   C + +C
Sbjct: 511  VDG----QCVCEDGFTGPDCAEL-------SCPNDCHGQGRCVNGQC 546



 Score =  224 bits (547), Expect = 4e-57
 Identities = 104/262 (39%), Positives = 140/262 (53%), Gaps = 18/262 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C  +G C+ G C+C  GF G DC +  CP  CS  G  +NG+C C+ G+ G++CS 
Sbjct: 376  CPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS- 434

Query: 938  RHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
               +   P DC+  G CV GKC C +G+KG  C ++ CP+  C  HG C+ G CVC  G+
Sbjct: 435  ---QLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMCVCDDGY 490

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC    +D  QC  DCS  G   VD Q C C   ++G DC++  C  +C   GRCV 
Sbjct: 491  TGEDC----RDR-QCPRDCSNRGLC-VDGQ-CVCEDGFTGPDCAELSCPNDCHGQGRCVN 543

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+ G+ C  + C + C   G+C +G C+C  G+ G  C    CP  C   GQC
Sbjct: 544  GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC 603

Query: 1117 RVDNDGRWECKCFDGWDGPDCT 1138
                 GR  C C +G+ G DC+
Sbjct: 604  ---VSGR--CICNEGYSGEDCS 620



 Score =  215 bits (525), Expect = 2e-54
 Identities = 96/231 (41%), Positives = 126/231 (54%), Gaps = 11/231 (4%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPNGCSG G C+ G C C  G+ G+DCS+  CP  C  RG  + G+C C  G+KG +CS 
Sbjct: 407  CPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS- 465

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
              D     DC+ HG CVNG C C  GY G+ C +  CP   CS  G C++G CVC+ G+ 
Sbjct: 466  --DMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRD-CSNRGLCVDGQCVCEDGFT 522

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC       L C  DC G G   V+ Q C CH  + G+DC ++ C  +C   GRCV  
Sbjct: 523  GPDCAE-----LSCPNDCHGQGRC-VNGQ-CVCHEGFMGKDCKEQRCPSDCHGQGRCVDG 575

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPR 1108
             C C  G++G  C    C + C   GQC +G C+C  G++G  C+    P+
Sbjct: 576  QCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPK 626



 Score =  210 bits (512), Expect = 8e-53
 Identities = 105/283 (37%), Positives = 140/283 (49%), Gaps = 16/283 (5%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C  +G C+ G C C  GF G+DCS+  CP  C+ +G+ +NG C C  G+   +CS 
Sbjct: 190  CPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGY-AADCS- 247

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
              + C VP    HG CV+G C C  G+ G  C +  C +  C   G C+E  CVC +G+ 
Sbjct: 248  -REICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVCDEGFT 305

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC       L C  DC   G       TC C   ++GEDC K  C   C   GRC   
Sbjct: 306  GEDC-----SELICPNDCFDRGR--CINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEG 358

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++G  CS + C A C   G+C +G C C  G+ G  C    CP  C+GHG+C 
Sbjct: 359  QCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC- 417

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCE 1160
            V+     +C C +G+ G DC+ L+      SR    +G   CE
Sbjct: 418  VNG----QCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCE 456



 Score =  180 bits (439), Expect = 5e-44
 Identities = 98/278 (35%), Positives = 138/278 (49%), Gaps = 24/278 (8%)

Query: 887  ECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQC--NPGWKGKECSLRHDECE 943
            +C  G  C  QP  G  D         CS RG +    C C   PGWKG  CS    EC 
Sbjct: 139  QCTAGAGCCLQPATGRLDTRP-----FCSGRGNFSTEGCGCVCEPGWKGPNCS--EPECP 191

Query: 944  VPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGT 1003
              +C+  G C++G+C C  G+ G+ C ++ CP   C+  G C+ G C+C +G+  ADC  
Sbjct: 192  -GNCHLRGRCIDGQCICDDGFTGEDCSQLACPSD-CNDQGKCVNGVCICFEGY-AADCSR 248

Query: 1004 MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
                 +  +P    HGT  VD   C CH  ++G+DC+K +C   C   GRCV   C C  
Sbjct: 249  ----EICPVPCSEEHGTC-VDG-LCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDE 302

Query: 1064 GWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            G++GE CS  +C   C + G+C NGTC C  G+ G  C    CP +C   G+C    +G 
Sbjct: 303  GFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRC---EEG- 358

Query: 1124 WECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
             +C C +G+ G DC+  +      +R    DG  +C+D
Sbjct: 359  -QCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDD 395



 Score =  149 bits (361), Expect = 2e-34
 Identities = 68/166 (40%), Positives = 91/166 (54%), Gaps = 13/166 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CPN C   G C+ G C C  G+ G+DC    CP  CS RG  ++G+C C  G+ G +C+
Sbjct: 468  SCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCA 527

Query: 937  LRHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKG 995
                E   P DC+G G CVNG+C C  G+ GK C E  CP   C G G C++G C+C +G
Sbjct: 528  ----ELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCP-SDCHGQGRCVDGQCICHEG 582

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
            + G DCG        C  DC+  G     +  C C+  +SGEDCS+
Sbjct: 583  FTGLDCGQH-----SCPSDCNNLG--QCVSGRCICNEGYSGEDCSE 621



 Score =  103 bits (248), Expect = 7e-21
 Identities = 42/99 (42%), Positives = 58/99 (58%), Gaps = 3/99 (3%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
           +CPN C G+G C+ G C C  GF G DC +  CP  C  +G  ++G+C C+ G+ G +C 
Sbjct: 530 SCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 589

Query: 937 LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP 975
            +H  C   DCN  G CV+G+C C  GY G+ C E+  P
Sbjct: 590 -QH-SCP-SDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 625



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 14/31 (45%), Positives = 22/31 (70%)

Query: 876 HNCPNGCSGKGECLMGHCQCQPGFGGDDCSK 906
           H+CP+ C+  G+C+ G C C  G+ G+DCS+
Sbjct: 591 HSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 621


>AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachion)
            protein.
          Length = 2201

 Score =  230 bits (562), Expect = 7e-59
 Identities = 103/261 (39%), Positives = 139/261 (53%), Gaps = 18/261 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP+ C  +G C  G C C  GF G DCS+  CP  C  RG  ++G C+C+ G+ G +C  
Sbjct: 346  CPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCG- 404

Query: 938  RHDECEVPD-CNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
               E + P+ C+GHG CVNG+C C  GY G+ C ++ CP+  C   G C+EG CVC++G+
Sbjct: 405  ---ELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPND-CHSRGRCVEGKCVCEQGF 460

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
            KG DC  M      C  DC  HG        C C   ++GEDC    C  +C   G CV 
Sbjct: 461  KGYDCSDMS-----CPNDCHQHGR--CVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD 513

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C+   C   C   G+C NG C+C  G+ G+ C  + CP  C G G+C
Sbjct: 514  GQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRC 573

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
             VD     +C C +G+ G DC
Sbjct: 574  -VDG----QCICHEGFTGLDC 589



 Score =  228 bits (557), Expect = 3e-58
 Identities = 114/287 (39%), Positives = 144/287 (50%), Gaps = 23/287 (8%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C N C  +G C+   C C  GF G+DCS+ +CP  C  RG  ING C C  G+ G++C  
Sbjct: 284  CLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCG- 342

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C    C+  G C  G+C C  G+ G  C E  CP   C   G C++G C C  G+ 
Sbjct: 343  -KPTCPHA-CHTQGRCEEGQCVCDEGFAGVDCSEKRCP-ADCHNRGRCVDGRCECDDGFT 399

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            GADCG      L+C   CSGHG   V+ Q C C   ++GEDCS+  C  +C   GRCV  
Sbjct: 400  GADCGE-----LKCPNGCSGHGRC-VNGQ-CVCDEGYTGEDCSQLRCPNDCHSRGRCVEG 452

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+ G  CS   C   C +HG+C NG C+C  G+ G  C    CPR C+  G C 
Sbjct: 453  KCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLC- 511

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
            VD     +C C DG+ GPDC  L       S  ND  G   C + +C
Sbjct: 512  VDG----QCVCEDGFTGPDCAEL-------SCPNDCHGQGRCVNGQC 547



 Score =  224 bits (547), Expect = 4e-57
 Identities = 104/262 (39%), Positives = 140/262 (53%), Gaps = 18/262 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C  +G C+ G C+C  GF G DC +  CP  CS  G  +NG+C C+ G+ G++CS 
Sbjct: 377  CPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS- 435

Query: 938  RHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
               +   P DC+  G CV GKC C +G+KG  C ++ CP+  C  HG C+ G CVC  G+
Sbjct: 436  ---QLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMCVCDDGY 491

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC    +D  QC  DCS  G   VD Q C C   ++G DC++  C  +C   GRCV 
Sbjct: 492  TGEDC----RDR-QCPRDCSNRGLC-VDGQ-CVCEDGFTGPDCAELSCPNDCHGQGRCVN 544

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+ G+ C  + C + C   G+C +G C+C  G+ G  C    CP  C   GQC
Sbjct: 545  GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC 604

Query: 1117 RVDNDGRWECKCFDGWDGPDCT 1138
                 GR  C C +G+ G DC+
Sbjct: 605  ---VSGR--CICNEGYSGEDCS 621



 Score =  216 bits (528), Expect = 9e-55
 Identities = 106/283 (37%), Positives = 141/283 (49%), Gaps = 15/283 (5%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C  +G C+ G C C  GF G+DCS+  CP  C+ +G+ +NG C C  G+ G +CS 
Sbjct: 190  CPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCS- 248

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
              + C VP    HG CV+G C C  G+ G  C +  C +  C   G C+E  CVC +G+ 
Sbjct: 249  -REICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVCDEGFT 306

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC       L C  DC   G       TC C   ++GEDC K  C   C   GRC   
Sbjct: 307  GEDC-----SELICPNDCFDRGR--CINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEG 359

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++G  CS + C A C   G+C +G C C  G+ G  C    CP  C+GHG+C 
Sbjct: 360  QCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC- 418

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCE 1160
            V+     +C C +G+ G DC+ L+      SR    +G   CE
Sbjct: 419  VNG----QCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCE 457



 Score =  215 bits (525), Expect = 2e-54
 Identities = 96/231 (41%), Positives = 126/231 (54%), Gaps = 11/231 (4%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPNGCSG G C+ G C C  G+ G+DCS+  CP  C  RG  + G+C C  G+KG +CS 
Sbjct: 408  CPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS- 466

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
              D     DC+ HG CVNG C C  GY G+ C +  CP   CS  G C++G CVC+ G+ 
Sbjct: 467  --DMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRD-CSNRGLCVDGQCVCEDGFT 523

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC       L C  DC G G   V+ Q C CH  + G+DC ++ C  +C   GRCV  
Sbjct: 524  GPDCAE-----LSCPNDCHGQGRC-VNGQ-CVCHEGFMGKDCKEQRCPSDCHGQGRCVDG 576

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPR 1108
             C C  G++G  C    C + C   GQC +G C+C  G++G  C+    P+
Sbjct: 577  QCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPK 627



 Score =  187 bits (455), Expect = 6e-46
 Identities = 99/278 (35%), Positives = 139/278 (50%), Gaps = 23/278 (8%)

Query: 887  ECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQC--NPGWKGKECSLRHDECE 943
            +C  G  C  QP  G  D         CS RG +    C C   PGWKG  CS    EC 
Sbjct: 139  QCTAGAGCCLQPATGRLDTRP-----FCSGRGNFSTEGCGCVCEPGWKGPNCS--EPECP 191

Query: 944  VPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGT 1003
              +C+  G C++G+C C  G+ G+ C ++ CP   C+  G C+ G C+C +G+ GADC  
Sbjct: 192  -GNCHLRGRCIDGQCICDDGFTGEDCSQLACPSD-CNDQGKCVNGVCICFEGYAGADCSR 249

Query: 1004 MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
                 +  +P    HGT  VD   C CH  ++G+DC+K +C   C   GRCV   C C  
Sbjct: 250  ----EICPVPCSEEHGTC-VDG-LCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDE 303

Query: 1064 GWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            G++GE CS  +C   C + G+C NGTC C  G+ G  C    CP +C   G+C    +G 
Sbjct: 304  GFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRC---EEG- 359

Query: 1124 WECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
             +C C +G+ G DC+  +      +R    DG  +C+D
Sbjct: 360  -QCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDD 396



 Score =  149 bits (361), Expect = 2e-34
 Identities = 68/166 (40%), Positives = 91/166 (54%), Gaps = 13/166 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CPN C   G C+ G C C  G+ G+DC    CP  CS RG  ++G+C C  G+ G +C+
Sbjct: 469  SCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCA 528

Query: 937  LRHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKG 995
                E   P DC+G G CVNG+C C  G+ GK C E  CP   C G G C++G C+C +G
Sbjct: 529  ----ELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCP-SDCHGQGRCVDGQCICHEG 583

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
            + G DCG        C  DC+  G     +  C C+  +SGEDCS+
Sbjct: 584  FTGLDCGQH-----SCPSDCNNLG--QCVSGRCICNEGYSGEDCSE 622



 Score =  103 bits (248), Expect = 7e-21
 Identities = 42/99 (42%), Positives = 58/99 (58%), Gaps = 3/99 (3%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
           +CPN C G+G C+ G C C  GF G DC +  CP  C  +G  ++G+C C+ G+ G +C 
Sbjct: 531 SCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 590

Query: 937 LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP 975
            +H  C   DCN  G CV+G+C C  GY G+ C E+  P
Sbjct: 591 -QH-SCP-SDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 14/31 (45%), Positives = 22/31 (70%)

Query: 876 HNCPNGCSGKGECLMGHCQCQPGFGGDDCSK 906
           H+CP+ C+  G+C+ G C C  G+ G+DCS+
Sbjct: 592 HSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 622


>AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein protein.
          Length = 2233

 Score =  230 bits (562), Expect = 7e-59
 Identities = 103/261 (39%), Positives = 139/261 (53%), Gaps = 18/261 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP+ C  +G C  G C C  GF G DCS+  CP  C  RG  ++G C+C+ G+ G +C  
Sbjct: 378  CPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCG- 436

Query: 938  RHDECEVPD-CNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
               E + P+ C+GHG CVNG+C C  GY G+ C ++ CP+  C   G C+EG CVC++G+
Sbjct: 437  ---ELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPND-CHSRGRCVEGKCVCEQGF 492

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
            KG DC  M      C  DC  HG        C C   ++GEDC    C  +C   G CV 
Sbjct: 493  KGYDCSDMS-----CPNDCHQHGR--CVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD 545

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C+   C   C   G+C NG C+C  G+ G+ C  + CP  C G G+C
Sbjct: 546  GQCVCEDGFTGPDCAELSCPNDCHGRGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRC 605

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
             VD     +C C +G+ G DC
Sbjct: 606  -VDG----QCICHEGFTGLDC 621



 Score =  228 bits (557), Expect = 3e-58
 Identities = 114/287 (39%), Positives = 144/287 (50%), Gaps = 23/287 (8%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C N C  +G C+   C C  GF G+DCS+ +CP  C  RG  ING C C  G+ G++C  
Sbjct: 316  CLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCG- 374

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C    C+  G C  G+C C  G+ G  C E  CP   C   G C++G C C  G+ 
Sbjct: 375  -KPTCPHA-CHTQGRCEEGQCVCDEGFAGVDCSEKRCP-ADCHNRGRCVDGRCECDDGFT 431

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            GADCG      L+C   CSGHG   V+ Q C C   ++GEDCS+  C  +C   GRCV  
Sbjct: 432  GADCGE-----LKCPNGCSGHGRC-VNGQ-CVCDEGYTGEDCSQLRCPNDCHSRGRCVEG 484

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+ G  CS   C   C +HG+C NG C+C  G+ G  C    CPR C+  G C 
Sbjct: 485  KCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLC- 543

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
            VD     +C C DG+ GPDC  L       S  ND  G   C + +C
Sbjct: 544  VDG----QCVCEDGFTGPDCAEL-------SCPNDCHGRGRCVNGQC 579



 Score =  224 bits (547), Expect = 4e-57
 Identities = 104/262 (39%), Positives = 140/262 (53%), Gaps = 18/262 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C  +G C+ G C+C  GF G DC +  CP  CS  G  +NG+C C+ G+ G++CS 
Sbjct: 409  CPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS- 467

Query: 938  RHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
               +   P DC+  G CV GKC C +G+KG  C ++ CP+  C  HG C+ G CVC  G+
Sbjct: 468  ---QLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMCVCDDGY 523

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC    +D  QC  DCS  G   VD Q C C   ++G DC++  C  +C   GRCV 
Sbjct: 524  TGEDC----RDR-QCPRDCSNRGLC-VDGQ-CVCEDGFTGPDCAELSCPNDCHGRGRCVN 576

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+ G+ C  + C + C   G+C +G C+C  G+ G  C    CP  C   GQC
Sbjct: 577  GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC 636

Query: 1117 RVDNDGRWECKCFDGWDGPDCT 1138
                 GR  C C +G+ G DC+
Sbjct: 637  ---VSGR--CICNEGYSGEDCS 653



 Score =  216 bits (528), Expect = 9e-55
 Identities = 106/283 (37%), Positives = 141/283 (49%), Gaps = 15/283 (5%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C  +G C+ G C C  GF G+DCS+  CP  C+ +G+ +NG C C  G+ G +CS 
Sbjct: 222  CPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCS- 280

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
              + C VP    HG CV+G C C  G+ G  C +  C +  C   G C+E  CVC +G+ 
Sbjct: 281  -REICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVCDEGFT 338

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC       L C  DC   G       TC C   ++GEDC K  C   C   GRC   
Sbjct: 339  GEDC-----SELICPNDCFDRGR--CINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEG 391

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++G  CS + C A C   G+C +G C C  G+ G  C    CP  C+GHG+C 
Sbjct: 392  QCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC- 450

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCE 1160
            V+     +C C +G+ G DC+ L+      SR    +G   CE
Sbjct: 451  VNG----QCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCE 489



 Score =  215 bits (525), Expect = 2e-54
 Identities = 96/231 (41%), Positives = 126/231 (54%), Gaps = 11/231 (4%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPNGCSG G C+ G C C  G+ G+DCS+  CP  C  RG  + G+C C  G+KG +CS 
Sbjct: 440  CPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS- 498

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
              D     DC+ HG CVNG C C  GY G+ C +  CP   CS  G C++G CVC+ G+ 
Sbjct: 499  --DMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRD-CSNRGLCVDGQCVCEDGFT 555

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC       L C  DC G G   V+ Q C CH  + G+DC ++ C  +C   GRCV  
Sbjct: 556  GPDCAE-----LSCPNDCHGRGRC-VNGQ-CVCHEGFMGKDCKEQRCPSDCHGQGRCVDG 608

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPR 1108
             C C  G++G  C    C + C   GQC +G C+C  G++G  C+    P+
Sbjct: 609  QCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPK 659



 Score =  187 bits (455), Expect = 6e-46
 Identities = 99/278 (35%), Positives = 139/278 (50%), Gaps = 23/278 (8%)

Query: 887  ECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQC--NPGWKGKECSLRHDECE 943
            +C  G  C  QP  G  D         CS RG +    C C   PGWKG  CS    EC 
Sbjct: 171  QCTAGAGCCLQPATGRLDTRP-----FCSGRGNFSTEGCGCVCEPGWKGPNCS--EPECP 223

Query: 944  VPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGT 1003
              +C+  G C++G+C C  G+ G+ C ++ CP   C+  G C+ G C+C +G+ GADC  
Sbjct: 224  -GNCHLRGRCIDGQCICDDGFTGEDCSQLACPSD-CNDQGKCVNGVCICFEGYAGADCSR 281

Query: 1004 MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
                 +  +P    HGT  VD   C CH  ++G+DC+K +C   C   GRCV   C C  
Sbjct: 282  ----EICPVPCSEEHGTC-VDG-LCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDE 335

Query: 1064 GWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            G++GE CS  +C   C + G+C NGTC C  G+ G  C    CP +C   G+C    +G 
Sbjct: 336  GFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRC---EEG- 391

Query: 1124 WECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
             +C C +G+ G DC+  +      +R    DG  +C+D
Sbjct: 392  -QCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDD 428



 Score =  149 bits (361), Expect = 2e-34
 Identities = 68/166 (40%), Positives = 91/166 (54%), Gaps = 13/166 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CPN C   G C+ G C C  G+ G+DC    CP  CS RG  ++G+C C  G+ G +C+
Sbjct: 501  SCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCA 560

Query: 937  LRHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKG 995
                E   P DC+G G CVNG+C C  G+ GK C E  CP   C G G C++G C+C +G
Sbjct: 561  ----ELSCPNDCHGRGRCVNGQCVCHEGFMGKDCKEQRCP-SDCHGQGRCVDGQCICHEG 615

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
            + G DCG        C  DC+  G     +  C C+  +SGEDCS+
Sbjct: 616  FTGLDCGQH-----SCPSDCNNLG--QCVSGRCICNEGYSGEDCSE 654



 Score =  104 bits (249), Expect = 6e-21
 Identities = 42/99 (42%), Positives = 58/99 (58%), Gaps = 3/99 (3%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
           +CPN C G+G C+ G C C  GF G DC +  CP  C  +G  ++G+C C+ G+ G +C 
Sbjct: 563 SCPNDCHGRGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 622

Query: 937 LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP 975
            +H  C   DCN  G CV+G+C C  GY G+ C E+  P
Sbjct: 623 -QH-SCP-SDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 658



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 14/31 (45%), Positives = 22/31 (70%)

Query: 876 HNCPNGCSGKGECLMGHCQCQPGFGGDDCSK 906
           H+CP+ C+  G+C+ G C C  G+ G+DCS+
Sbjct: 624 HSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 654


>X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein.
          Length = 2201

 Score =  229 bits (561), Expect = 9e-59
 Identities = 103/261 (39%), Positives = 139/261 (53%), Gaps = 18/261 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP+ C  +G C  G C C  GF G DCS+  CP  C  RG  ++G C+C+ G+ G +C  
Sbjct: 346  CPHACHTQGRCEEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCG- 404

Query: 938  RHDECEVPD-CNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
               E + P+ C+GHG CVNG+C C  GY G+ C ++ CP+  C   G C+EG CVC++G+
Sbjct: 405  ---ELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPND-CHSRGRCVEGKCVCEQGF 460

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
            KG DC  M      C  DC  HG        C C   ++GEDC    C  +C   G CV 
Sbjct: 461  KGYDCSDMS-----CPNDCHQHGR--CVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD 513

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C+   C   C   G+C NG C+C  G+ G+ C  + CP  C G G+C
Sbjct: 514  GQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRC 573

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
             VD     +C C +G+ G DC
Sbjct: 574  -VDG----QCICHEGFTGLDC 589



 Score =  228 bits (557), Expect = 3e-58
 Identities = 114/287 (39%), Positives = 144/287 (50%), Gaps = 23/287 (8%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C N C  +G C+   C C  GF G+DCS+ +CP  C  RG  ING C C  G+ G++C  
Sbjct: 284  CLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCG- 342

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C    C+  G C  G+C C  G+ G  C E  CP   C   G C++G C C  G+ 
Sbjct: 343  -KPTCPHA-CHTQGRCEEGQCVCDEGFAGLDCSEKRCP-ADCHNRGRCVDGRCECDDGFT 399

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            GADCG      L+C   CSGHG   V+ Q C C   ++GEDCS+  C  +C   GRCV  
Sbjct: 400  GADCGE-----LKCPNGCSGHGRC-VNGQ-CVCDEGYTGEDCSQLRCPNDCHSRGRCVEG 452

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+ G  CS   C   C +HG+C NG C+C  G+ G  C    CPR C+  G C 
Sbjct: 453  KCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLC- 511

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
            VD     +C C DG+ GPDC  L       S  ND  G   C + +C
Sbjct: 512  VDG----QCVCEDGFTGPDCAEL-------SCPNDCHGQGRCVNGQC 547



 Score =  224 bits (547), Expect = 4e-57
 Identities = 104/262 (39%), Positives = 140/262 (53%), Gaps = 18/262 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C  +G C+ G C+C  GF G DC +  CP  CS  G  +NG+C C+ G+ G++CS 
Sbjct: 377  CPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS- 435

Query: 938  RHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
               +   P DC+  G CV GKC C +G+KG  C ++ CP+  C  HG C+ G CVC  G+
Sbjct: 436  ---QLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMCVCDDGY 491

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC    +D  QC  DCS  G   VD Q C C   ++G DC++  C  +C   GRCV 
Sbjct: 492  TGEDC----RDR-QCPRDCSNRGLC-VDGQ-CVCEDGFTGPDCAELSCPNDCHGQGRCVN 544

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+ G+ C  + C + C   G+C +G C+C  G+ G  C    CP  C   GQC
Sbjct: 545  GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC 604

Query: 1117 RVDNDGRWECKCFDGWDGPDCT 1138
                 GR  C C +G+ G DC+
Sbjct: 605  ---VSGR--CICNEGYSGEDCS 621



 Score =  216 bits (527), Expect = 1e-54
 Identities = 106/283 (37%), Positives = 141/283 (49%), Gaps = 15/283 (5%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C  +G C+ G C C  GF G+DCS+  CP  C+ +G+ +NG C C  G+ G +CS 
Sbjct: 190  CPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCS- 248

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
              + C VP    HG CV+G C C  G+ G  C +  C +  C   G C+E  CVC +G+ 
Sbjct: 249  -REICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVCDEGFT 306

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC       L C  DC   G       TC C   ++GEDC K  C   C   GRC   
Sbjct: 307  GEDC-----SELICPNDCFDRGR--CINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEG 359

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++G  CS + C A C   G+C +G C C  G+ G  C    CP  C+GHG+C 
Sbjct: 360  QCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC- 418

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCE 1160
            V+     +C C +G+ G DC+ L+      SR    +G   CE
Sbjct: 419  VNG----QCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCE 457



 Score =  215 bits (525), Expect = 2e-54
 Identities = 96/231 (41%), Positives = 126/231 (54%), Gaps = 11/231 (4%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPNGCSG G C+ G C C  G+ G+DCS+  CP  C  RG  + G+C C  G+KG +CS 
Sbjct: 408  CPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS- 466

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
              D     DC+ HG CVNG C C  GY G+ C +  CP   CS  G C++G CVC+ G+ 
Sbjct: 467  --DMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRD-CSNRGLCVDGQCVCEDGFT 523

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC       L C  DC G G   V+ Q C CH  + G+DC ++ C  +C   GRCV  
Sbjct: 524  GPDCAE-----LSCPNDCHGQGRC-VNGQ-CVCHEGFMGKDCKEQRCPSDCHGQGRCVDG 576

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPR 1108
             C C  G++G  C    C + C   GQC +G C+C  G++G  C+    P+
Sbjct: 577  QCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPK 627



 Score =  186 bits (454), Expect = 8e-46
 Identities = 99/278 (35%), Positives = 139/278 (50%), Gaps = 23/278 (8%)

Query: 887  ECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQC--NPGWKGKECSLRHDECE 943
            +C  G  C  QP  G  D         CS RG +    C C   PGWKG  CS    EC 
Sbjct: 139  QCTAGAGCCLQPATGRLDTRP-----FCSGRGNFSTEGCGCVCEPGWKGPNCS--EPECP 191

Query: 944  VPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGT 1003
              +C+  G C++G+C C  G+ G+ C ++ CP   C+  G C+ G C+C +G+ GADC  
Sbjct: 192  -GNCHLRGRCIDGQCICDDGFTGEDCSQLACPSD-CNDQGKCVNGVCICFEGYAGADCSR 249

Query: 1004 MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
                 +  +P    HGT  VD   C CH  ++G+DC+K +C   C   GRCV   C C  
Sbjct: 250  ----EICPVPCSEEHGTC-VDG-LCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDE 303

Query: 1064 GWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            G++GE CS  +C   C + G+C NGTC C  G+ G  C    CP +C   G+C    +G 
Sbjct: 304  GFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRC---EEG- 359

Query: 1124 WECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
             +C C +G+ G DC+  +      +R    DG  +C+D
Sbjct: 360  -QCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDD 396



 Score =  149 bits (361), Expect = 2e-34
 Identities = 68/166 (40%), Positives = 91/166 (54%), Gaps = 13/166 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CPN C   G C+ G C C  G+ G+DC    CP  CS RG  ++G+C C  G+ G +C+
Sbjct: 469  SCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCA 528

Query: 937  LRHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKG 995
                E   P DC+G G CVNG+C C  G+ GK C E  CP   C G G C++G C+C +G
Sbjct: 529  ----ELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCP-SDCHGQGRCVDGQCICHEG 583

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
            + G DCG        C  DC+  G     +  C C+  +SGEDCS+
Sbjct: 584  FTGLDCGQH-----SCPSDCNNLG--QCVSGRCICNEGYSGEDCSE 622



 Score =  103 bits (248), Expect = 7e-21
 Identities = 42/99 (42%), Positives = 58/99 (58%), Gaps = 3/99 (3%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
           +CPN C G+G C+ G C C  GF G DC +  CP  C  +G  ++G+C C+ G+ G +C 
Sbjct: 531 SCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 590

Query: 937 LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP 975
            +H  C   DCN  G CV+G+C C  GY G+ C E+  P
Sbjct: 591 -QH-SCP-SDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 14/31 (45%), Positives = 22/31 (70%)

Query: 876 HNCPNGCSGKGECLMGHCQCQPGFGGDDCSK 906
           H+CP+ C+  G+C+ G C C  G+ G+DCS+
Sbjct: 592 HSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 622


>M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein.
          Length = 2203

 Score =  229 bits (561), Expect = 9e-59
 Identities = 103/261 (39%), Positives = 139/261 (53%), Gaps = 18/261 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP+ C  +G C  G C C  GF G DCS+  CP  C  RG  ++G C+C+ G+ G +C  
Sbjct: 346  CPHACHTQGRCEEGQCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCG- 404

Query: 938  RHDECEVPD-CNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
               E + P+ C+GHG CVNG+C C  GY G+ C ++ CP+  C   G C+EG CVC++G+
Sbjct: 405  ---ELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPND-CHSRGRCVEGKCVCEQGF 460

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
            KG DC  M      C  DC  HG        C C   ++GEDC    C  +C   G CV 
Sbjct: 461  KGYDCSDMS-----CPNDCHQHGR--CVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD 513

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G++G  C+   C   C   G+C NG C+C  G+ G+ C  + CP  C G G+C
Sbjct: 514  GQCVCEDGFTGPDCAELSCPNDCHGRGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRC 573

Query: 1117 RVDNDGRWECKCFDGWDGPDC 1137
             VD     +C C +G+ G DC
Sbjct: 574  -VDG----QCICHEGFTGLDC 589



 Score =  228 bits (557), Expect = 3e-58
 Identities = 114/287 (39%), Positives = 144/287 (50%), Gaps = 23/287 (8%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C N C  +G C+   C C  GF G+DCS+ +CP  C  RG  ING C C  G+ G++C  
Sbjct: 284  CLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCG- 342

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C    C+  G C  G+C C  G+ G  C E  CP   C   G C++G C C  G+ 
Sbjct: 343  -KPTCPHA-CHTQGRCEEGQCVCDEGFAGLDCSEKRCP-ADCHNRGRCVDGRCECDDGFT 399

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            GADCG      L+C   CSGHG   V+ Q C C   ++GEDCS+  C  +C   GRCV  
Sbjct: 400  GADCGE-----LKCPNGCSGHGRC-VNGQ-CVCDEGYTGEDCSQLRCPNDCHSRGRCVEG 452

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G+ G  CS   C   C +HG+C NG C+C  G+ G  C    CPR C+  G C 
Sbjct: 453  KCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLC- 511

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
            VD     +C C DG+ GPDC  L       S  ND  G   C + +C
Sbjct: 512  VDG----QCVCEDGFTGPDCAEL-------SCPNDCHGRGRCVNGQC 547



 Score =  224 bits (547), Expect = 4e-57
 Identities = 104/262 (39%), Positives = 140/262 (53%), Gaps = 18/262 (6%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C  +G C+ G C+C  GF G DC +  CP  CS  G  +NG+C C+ G+ G++CS 
Sbjct: 377  CPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS- 435

Query: 938  RHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGW 996
               +   P DC+  G CV GKC C +G+KG  C ++ CP+  C  HG C+ G CVC  G+
Sbjct: 436  ---QLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMCVCDDGY 491

Query: 997  KGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG 1056
             G DC    +D  QC  DCS  G   VD Q C C   ++G DC++  C  +C   GRCV 
Sbjct: 492  TGEDC----RDR-QCPRDCSNRGLC-VDGQ-CVCEDGFTGPDCAELSCPNDCHGRGRCVN 544

Query: 1057 ESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQC 1116
              C C  G+ G+ C  + C + C   G+C +G C+C  G+ G  C    CP  C   GQC
Sbjct: 545  GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC 604

Query: 1117 RVDNDGRWECKCFDGWDGPDCT 1138
                 GR  C C +G+ G DC+
Sbjct: 605  ---VSGR--CICNEGYSGEDCS 621



 Score =  216 bits (527), Expect = 1e-54
 Identities = 106/283 (37%), Positives = 141/283 (49%), Gaps = 15/283 (5%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP  C  +G C+ G C C  GF G+DCS+  CP  C+ +G+ +NG C C  G+ G +CS 
Sbjct: 190  CPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCS- 248

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
              + C VP    HG CV+G C C  G+ G  C +  C +  C   G C+E  CVC +G+ 
Sbjct: 249  -REICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVCDEGFT 306

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC       L C  DC   G       TC C   ++GEDC K  C   C   GRC   
Sbjct: 307  GEDC-----SELICPNDCFDRGR--CINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEG 359

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C C  G++G  CS + C A C   G+C +G C C  G+ G  C    CP  C+GHG+C 
Sbjct: 360  QCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC- 418

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCE 1160
            V+     +C C +G+ G DC+ L+      SR    +G   CE
Sbjct: 419  VNG----QCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCE 457



 Score =  215 bits (525), Expect = 2e-54
 Identities = 96/231 (41%), Positives = 126/231 (54%), Gaps = 11/231 (4%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPNGCSG G C+ G C C  G+ G+DCS+  CP  C  RG  + G+C C  G+KG +CS 
Sbjct: 408  CPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS- 466

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
              D     DC+ HG CVNG C C  GY G+ C +  CP   CS  G C++G CVC+ G+ 
Sbjct: 467  --DMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRD-CSNRGLCVDGQCVCEDGFT 523

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC       L C  DC G G   V+ Q C CH  + G+DC ++ C  +C   GRCV  
Sbjct: 524  GPDCAE-----LSCPNDCHGRGRC-VNGQ-CVCHEGFMGKDCKEQRCPSDCHGQGRCVDG 576

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPR 1108
             C C  G++G  C    C + C   GQC +G C+C  G++G  C+    P+
Sbjct: 577  QCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPK 627



 Score =  186 bits (454), Expect = 8e-46
 Identities = 99/278 (35%), Positives = 139/278 (50%), Gaps = 23/278 (8%)

Query: 887  ECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQC--NPGWKGKECSLRHDECE 943
            +C  G  C  QP  G  D         CS RG +    C C   PGWKG  CS    EC 
Sbjct: 139  QCTAGAGCCLQPATGRLDTRP-----FCSGRGNFSTEGCGCVCEPGWKGPNCS--EPECP 191

Query: 944  VPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGT 1003
              +C+  G C++G+C C  G+ G+ C ++ CP   C+  G C+ G C+C +G+ GADC  
Sbjct: 192  -GNCHLRGRCIDGQCICDDGFTGEDCSQLACPSD-CNDQGKCVNGVCICFEGYAGADCSR 249

Query: 1004 MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
                 +  +P    HGT  VD   C CH  ++G+DC+K +C   C   GRCV   C C  
Sbjct: 250  ----EICPVPCSEEHGTC-VDG-LCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDE 303

Query: 1064 GWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            G++GE CS  +C   C + G+C NGTC C  G+ G  C    CP +C   G+C    +G 
Sbjct: 304  GFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRC---EEG- 359

Query: 1124 WECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
             +C C +G+ G DC+  +      +R    DG  +C+D
Sbjct: 360  -QCVCDEGFAGLDCSEKRCPADCHNRGRCVDGRCECDD 396



 Score =  149 bits (361), Expect = 2e-34
 Identities = 68/166 (40%), Positives = 91/166 (54%), Gaps = 13/166 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CPN C   G C+ G C C  G+ G+DC    CP  CS RG  ++G+C C  G+ G +C+
Sbjct: 469  SCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCA 528

Query: 937  LRHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKG 995
                E   P DC+G G CVNG+C C  G+ GK C E  CP   C G G C++G C+C +G
Sbjct: 529  ----ELSCPNDCHGRGRCVNGQCVCHEGFMGKDCKEQRCP-SDCHGQGRCVDGQCICHEG 583

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
            + G DCG        C  DC+  G     +  C C+  +SGEDCS+
Sbjct: 584  FTGLDCGQH-----SCPSDCNNLG--QCVSGRCICNEGYSGEDCSE 622



 Score =  104 bits (249), Expect = 6e-21
 Identities = 42/99 (42%), Positives = 58/99 (58%), Gaps = 3/99 (3%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
           +CPN C G+G C+ G C C  GF G DC +  CP  C  +G  ++G+C C+ G+ G +C 
Sbjct: 531 SCPNDCHGRGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 590

Query: 937 LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP 975
            +H  C   DCN  G CV+G+C C  GY G+ C E+  P
Sbjct: 591 -QH-SCP-SDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 14/31 (45%), Positives = 22/31 (70%)

Query: 876 HNCPNGCSGKGECLMGHCQCQPGFGGDDCSK 906
           H+CP+ C+  G+C+ G C C  G+ G+DCS+
Sbjct: 592 HSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 622


>AK001336-1|BAA91633.1| 1045|Homo sapiens protein ( Homo sapiens cDNA
            FLJ10474 fis, clone NT2RP2000067. ).
          Length = 1045

 Score =  195 bits (476), Expect = 2e-48
 Identities = 136/492 (27%), Positives = 239/492 (48%), Gaps = 23/492 (4%)

Query: 2094 ILGESYPVPAKQGTEVGGDLA-NRFEWRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLL 2152
            + G + P  AK+   + G+   N  EWR+   R   ++GK    V   GRKLRVNG NLL
Sbjct: 69   LAGTANPTVAKRNMTLPGENGQNLVEWRF---RKEQAQGK----VNVFGRKLRVNGRNLL 121

Query: 2153 TLEYDRDTSTVAVFMDDKYELLNVTYDRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSW 2212
            ++++DR T T  ++ D +  LL + YD +  P  W P S + + V + Y    ++     
Sbjct: 122  SVDFDRTTKTEKIYDDHRKFLLRIAYDTSGHPTLWLPSSKLMA-VNVTYSSTGQIASIQR 180

Query: 2213 GDLNETYGFDRAGRLHEIRYGDGSSLAYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQ 2272
            G  +E   +D  GR+    + DG + +Y++ +   S+ L + + R   Y+ +YD    L 
Sbjct: 181  GTTSEKVDYDGQGRIVSRVFADGKTWSYTYLE--KSMVLLLHSQR--QYIFEYDMWDRLS 236

Query: 2273 NLTTPRGHIHTFALMTSLGYFKYQYFSPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVY 2332
             +T P    HT   + S+GY++  Y  P +       YN++G +L   F   S ++L+ Y
Sbjct: 237  AITMPSVARHTMQTIRSIGYYRNIYNPPESNASIITDYNEEGLLLQTAFLGTSRRVLFKY 296

Query: 2333 DGTGKLETVLAGASAIRYVYHDNTHLVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSK 2392
                +L  +L  ++ + + Y +   ++K V +    +     Y+   G L D ++   S+
Sbjct: 297  RRQTRLSEILYDSTRVSFTYDETAGVLKTVNLQSDGFICTIRYR-QIGPLIDRQIFRFSE 355

Query: 2393 SGLNNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRT 2452
             G+ NA F Y YD + R++++   IN   +P    +++   G +E      +     N+ 
Sbjct: 356  DGMVNARFDYSYDNSFRVTSMQGVINETPLPIDLYQFDDISGKVEQFGKFGVIYYDINQI 415

Query: 2453 VMQDTSKQFFTITDYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSE 2512
            +   T+   +T   +D HGRIK     I    ++ + ++YD   R+  +++ IG  A + 
Sbjct: 416  I--STAVMTYT-KHFDAHGRIKEIQYEIFRSLMYWITIQYDNMGRVTKREIKIGPFANTT 472

Query: 2513 RISYNY--DGHLMEVVGSEDDL-KYNYDENGNVIGIIEHGEKRY--LGYDIGDRVVQYGD 2567
            + +Y Y  DG L  V  +E  + +YNYD NGN+  +      R   L YD+ DR+ + GD
Sbjct: 473  KYAYEYDVDGQLQTVYLNEKIMWRYNYDLNGNLHLLNPSNSARLTPLRYDLRDRITRLGD 532

Query: 2568 VEFSSYDGRGFV 2579
            V++   D  GF+
Sbjct: 533  VQY-RLDEDGFL 543



 Score =  171 bits (417), Expect = 2e-41
 Identities = 121/387 (31%), Positives = 194/387 (50%), Gaps = 19/387 (4%)

Query: 2580 GDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNTNLIYLENRLYDPVVGQWMTPSW 2639
            G ++K+I+ + +G+I  DSN  F + + FHGG++D  T LI+   R YD + G+W TP  
Sbjct: 656  GLMLKQIQYTAYGEIYFDSNIDFQLVIGFHGGLYDPLTKLIHFGERDYDILAGRWTTPDI 715

Query: 2640 EHLATKLSLPTDIFIYRFKNNDPINKQQNVP-YMTSLNSWLQLYGYDL-NKMMGSKYIND 2697
            E        P    +Y F+NN+P +K  +V  Y+T +NSWL  +G+ L N + G      
Sbjct: 716  EIWKRIGKDPAPFNLYMFRNNNPASKIHDVKDYITDVNSWLVTFGFHLHNAIPGFPVPKF 775

Query: 2698 MIFQPMTSVTAAQLAPDFGVMSGLQC-IIEKVNDKLSDIEFVPTPLLKMEPITRNLLPRV 2756
             + +P   +  +Q   D   + G+Q  +  +    LS  +     + +            
Sbjct: 776  DLTEPSYELVKSQQWDDIPPIFGVQQQVARQAKAFLSLGKMAEVQVSRRRAGGAQSWLWF 835

Query: 2757 SYKRGVFGEGVLISRVDGRAFISVADGANSVVEDVI--TTVFNNSYFLD-VHFSIHDQDV 2813
            +  + + G+GV+++   GR   +V + AN   ED I    V NN+++L+ +HF+I  +D 
Sbjct: 836  ATVKSLIGKGVMLAVSQGRVQTNVLNIAN---EDCIKVAAVLNNAFYLENLHFTIEGKDT 892

Query: 2814 FYFVKDNSLKIRDDMEELRRLSGK--------FNVSQDETNDQGLEVRVHAVGKGSAQAV 2865
             YF+K  + +   D+  LR  SG+          VSQ  T   G   R   V        
Sbjct: 893  HYFIKTTTPE--SDLGTLRLTSGRKALENGINVTVSQSTTVVNGRTRRFADVEMQFGALA 950

Query: 2866 IVLRYGVDPAQERIKLLKHAHKRAATRAWEREKALVAAGWEGRGSWTEEEKEELISHGIV 2925
            + +RYG+   +E+ ++L+ A +RA  RAW RE+  V  G EG   WTE EK +L+S G V
Sbjct: 951  LHVRYGMTLDEEKARILEQARQRALARAWAREQQRVRDGEEGARLWTEGEKRQLLSAGKV 1010

Query: 2926 DGWAARDVHSISKYPQLADDPANIVFV 2952
             G+    V S+ +YP+LAD   NI F+
Sbjct: 1011 QGYDGYYVLSVEQYPELADSANNIQFL 1037


>AK001748-1|BAA91879.1|  964|Homo sapiens protein ( Homo sapiens cDNA
            FLJ10886 fis, clone NT2RP4001966. ).
          Length = 964

 Score =  191 bits (465), Expect = 4e-47
 Identities = 131/470 (27%), Positives = 229/470 (48%), Gaps = 22/470 (4%)

Query: 2115 NRFEWRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVAVFMDDKYELL 2174
            N  EWR+   R   ++GK    V   GRKLRVNG NLL++++DR T T  ++ D +  LL
Sbjct: 10   NLVEWRF---RKEQAQGK----VNVFGRKLRVNGRNLLSVDFDRTTKTEKIYDDHRKFLL 62

Query: 2175 NVTYDRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRAGRLHEIRYGD 2234
             + YD +  P  W P S + + V + Y    ++     G  +E   +D  GR+    + D
Sbjct: 63   RIAYDTSGHPTLWLPSSKLMA-VNVTYSSTGQIASIQRGTTSEKVDYDGQGRIVSRVFAD 121

Query: 2235 GSSLAYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTFALMTSLGYFK 2294
            G + +Y++ +   S+ L + + R   Y+ +YD    L  +T P    HT   + S+GY++
Sbjct: 122  GKTWSYTYLE--KSMVLLLHSQR--QYIFEYDMWDRLSAITMPSVARHTMQTIRSIGYYR 177

Query: 2295 YQYFSPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAGASAIRYVYHD 2354
              Y  P +       YN++G +L   F   S ++L+ Y    +L  +L  ++ + + Y +
Sbjct: 178  NIYNPPESNASIITDYNEEGLLLQTAFLGTSRRVLFKYRRQTRLSEILYDSTRVSFTYDE 237

Query: 2355 NTHLVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQYDGNARLSTID 2414
               ++K V +    +     Y+   G L D ++   S+ G+ NA F Y YD + R++++ 
Sbjct: 238  TAGVLKTVNLQSDGFICTIRYR-QIGPLIDRQIFRFSEDGMVNARFDYSYDNSFRVTSMQ 296

Query: 2415 VNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTITDYDDHGRIK 2474
              IN   +P    +++   G +E      +     N+ +   T+   +T   +D HGRIK
Sbjct: 297  GVINETPLPIDLYQFDDISGKVEQFGKFGVIYYDINQII--STAVMTYT-KHFDAHGRIK 353

Query: 2475 TFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHLMEVVGSEDDL 2532
                 I    ++ + ++YD   R+  +++ IG  A + + +Y Y  DG L  V  +E  +
Sbjct: 354  EIQYEIFRSLMYWITIQYDNMGRVTKREIKIGPFANTTKYAYEYDVDGQLQTVYLNEKIM 413

Query: 2533 -KYNYDENGNVIGIIEHGEKRY--LGYDIGDRVVQYGDVEFSSYDGRGFV 2579
             +YNYD NGN+  +      R   L YD+ DR+ + GDV++   D  GF+
Sbjct: 414  WRYNYDLNGNLHLLNPSNSARLTPLRYDLRDRITRLGDVQY-RLDEDGFL 462



 Score =  171 bits (417), Expect = 2e-41
 Identities = 121/387 (31%), Positives = 194/387 (50%), Gaps = 19/387 (4%)

Query: 2580 GDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNTNLIYLENRLYDPVVGQWMTPSW 2639
            G ++K+I+ + +G+I  DSN  F + + FHGG++D  T LI+   R YD + G+W TP  
Sbjct: 575  GLMLKQIQYTAYGEIYFDSNIDFQLVIGFHGGLYDPLTKLIHFGERDYDILAGRWTTPDI 634

Query: 2640 EHLATKLSLPTDIFIYRFKNNDPINKQQNVP-YMTSLNSWLQLYGYDL-NKMMGSKYIND 2697
            E        P    +Y F+NN+P +K  +V  Y+T +NSWL  +G+ L N + G      
Sbjct: 635  EIWKRIGKDPAPFNLYMFRNNNPASKIHDVKDYITDVNSWLVTFGFHLHNAIPGFPVPKF 694

Query: 2698 MIFQPMTSVTAAQLAPDFGVMSGLQC-IIEKVNDKLSDIEFVPTPLLKMEPITRNLLPRV 2756
             + +P   +  +Q   D   + G+Q  +  +    LS  +     + +            
Sbjct: 695  DLTEPSYELVKSQQWDDIPPIFGVQQQVARQAKAFLSLGKMAEVQVSRRRAGGAQSWLWF 754

Query: 2757 SYKRGVFGEGVLISRVDGRAFISVADGANSVVEDVI--TTVFNNSYFLD-VHFSIHDQDV 2813
            +  + + G+GV+++   GR   +V + AN   ED I    V NN+++L+ +HF+I  +D 
Sbjct: 755  ATVKSLIGKGVMLAVSQGRVQTNVLNIAN---EDCIKVAAVLNNAFYLENLHFTIEGKDT 811

Query: 2814 FYFVKDNSLKIRDDMEELRRLSGK--------FNVSQDETNDQGLEVRVHAVGKGSAQAV 2865
             YF+K  + +   D+  LR  SG+          VSQ  T   G   R   V        
Sbjct: 812  HYFIKTTTPE--SDLGTLRLTSGRKALENGINVTVSQSTTVVNGRTRRFADVEMQFGALA 869

Query: 2866 IVLRYGVDPAQERIKLLKHAHKRAATRAWEREKALVAAGWEGRGSWTEEEKEELISHGIV 2925
            + +RYG+   +E+ ++L+ A +RA  RAW RE+  V  G EG   WTE EK +L+S G V
Sbjct: 870  LHVRYGMTLDEEKARILEQARQRALARAWAREQQRVRDGEEGARLWTEGEKRQLLSAGKV 929

Query: 2926 DGWAARDVHSISKYPQLADDPANIVFV 2952
             G+    V S+ +YP+LAD   NI F+
Sbjct: 930  QGYDGYYVLSVEQYPELADSANNIQFL 956


>BX537983-1|CAD97943.1| 1071|Homo sapiens hypothetical protein
            protein.
          Length = 1071

 Score =  188 bits (459), Expect = 2e-46
 Identities = 144/586 (24%), Positives = 265/586 (45%), Gaps = 35/586 (5%)

Query: 2004 GRLTSAVTPTGRIINLTFDLGLKGAIVRVSENNRKPVSILIK----GSSVNTKIGEAEKK 2059
            GRLT+   PTG++ +   D       V+V  +++  V+I       G+       +    
Sbjct: 3    GRLTNVTFPTGQVSSFRSDTD-SSVHVQVETSSKDDVTITTNLSASGAFYTLLQDQVRNS 61

Query: 2060 XXXXXXXXXXXXMPWGHVISTDTVPYTILAEIDPILGE-SYPVPAKQGTEVGGDLANRFE 2118
                        +  G  ++  T P+ +   ++P +G+ +  +P   G        N  E
Sbjct: 62   YYIGADGSLRLLLANGMEVALQTEPHLLAGTVNPTVGKRNVTLPIDNGL-------NLVE 114

Query: 2119 WRYFLRRLMSSKGKSSKAVAQIGRKLRVNGENLLTLEYDRDTSTVAVFMDDKYELLNVTY 2178
            WR   +R   ++G+    V   GR+LRV+  NLL+L +DR T T  ++ D +   L + Y
Sbjct: 115  WR---QRKEQARGQ----VTVFGRRLRVHNRNLLSLGFDRVTRTEKIYDDHRKFTLRILY 167

Query: 2179 DRTARPVKWGPRSGIFSEVELEYDRFNRLTRWSWGDLNETYGFDRAGRLHEIRYGDGSSL 2238
            D+  RP  W P S + + V + Y     +     G ++E   +D+AGR+    + DG + 
Sbjct: 168  DQAGRPSLWSPSSRL-NGVNVTYSPGGYIAGIQRGIMSERMEYDQAGRITSRIFADGKTW 226

Query: 2239 AYSFRDMFTSLPLKVTTPRGSDYLLDYDDSGALQNLTTPRGHIHTFALMTSLGYFKYQYF 2298
            +Y++ +   S+ L + + R   Y+ ++D +  L ++T P     T   + S+GY++  Y 
Sbjct: 227  SYTYLE--KSMVLLLHSQR--QYIFEFDKNDRLSSVTMPNVARQTLETIRSVGYYRNIYQ 282

Query: 2299 SPMNRHPYEIFYNDDGHILSKIFPHQSGKILYVYDGTGKLETVLAGASAIRYVYHDNTHL 2358
             P         + +DGH+L   +     +++Y Y    KL       + + + Y +   +
Sbjct: 283  PPEGNASVIQDFTEDGHLLHTFYLGTGRRVIYKYGKLSKLAETFYDTTKVSFTYDETAGM 342

Query: 2359 VKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQYDGNARLSTIDVNIN 2418
            +K + + +  +     Y+   G L D ++   ++ G+ NA F Y YD + R++++   IN
Sbjct: 343  LKTINLQNEGFTCTIRYR-QIGPLIDRQIFRFTEEGMVNARFDYNYDNSFRVTSMQAVIN 401

Query: 2419 SKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTITDYDDHGRIKTFLI 2478
               +P    +Y+   G  E      +     N+ +   T+        +D +GR+K    
Sbjct: 402  ETPLPIDLYRYDDVSGKTEQFGKFGVIYYDINQII---TTAVMTHTKHFDAYGRMKEVQY 458

Query: 2479 NIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHLMEVVGSEDDL-KYN 2535
             I    ++ + ++YD   R+  K+L +G  A + R SY Y  DG L  V  ++  L +Y+
Sbjct: 459  EIFRSLMYWMTVQYDNMGRVVKKELKVGPYANTTRYSYEYDADGQLQTVSINDKPLWRYS 518

Query: 2536 YDENGNVIGIIEHGEKRY--LGYDIGDRVVQYGDVEFSSYDGRGFV 2579
            YD NGN+  +      R   L YDI DR+ + GDV++   D  GF+
Sbjct: 519  YDLNGNLHLLSPGNSARLTPLRYDIRDRITRLGDVQY-KMDEDGFL 563



 Score =  177 bits (430), Expect = 7e-43
 Identities = 158/598 (26%), Positives = 280/598 (46%), Gaps = 65/598 (10%)

Query: 2396 NNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQ 2455
            N   + Y+YD + +L T+ +N    + P  R  Y+ N G+L  +S     R T  R  ++
Sbjct: 490  NTTRYSYEYDADGQLQTVSIN----DKPLWRYSYDLN-GNLHLLSPGNSARLTPLRYDIR 544

Query: 2456 DTSKQFFTIT-DYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERI 2514
            D   +   +    D+ G ++      +  D+F    EY++   +    +   + A S  +
Sbjct: 545  DRITRLGDVQYKMDEDGFLRQ-----RGGDIF----EYNSAGLL----IKAYNRAGSWSV 591

Query: 2515 SYNYDGHLMEVVGSEDD----LKYNYDENGN---VIGIIEHGEKRY--LGYDIGDRV--- 2562
             Y YDG L   V S+      L++ Y +  N   V  +  H       L YD+   +   
Sbjct: 592  RYRYDG-LGRRVSSKSSHSHHLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAM 650

Query: 2563 -VQYGDVEFSSYDGRGF-------VGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFD 2614
             +  GD  + + D  G         G ++K+I  + +G+I  D+NP+F + + +HGG++D
Sbjct: 651  ELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDTNPNFQIIIGYHGGLYD 710

Query: 2615 YNTNLIYLENRLYDPVVGQWMTPS---WEHLATKLSLPTDIFIYRFKNNDPINKQQNVP- 2670
              T L+++  R YD + G+W +P    W+HL++   +P +  +Y FKNN+PI+  Q++  
Sbjct: 711  PLTKLVHMGRRDYDVLAGRWTSPDHELWKHLSSSNVMPFN--LYMFKNNNPISNSQDIKC 768

Query: 2671 YMTSLNSWLQLYGYDLNKMMGSKYINDM-IFQPMTSVTAAQLA----PDFGVMSGLQCII 2725
            +MT +NSWL  +G+ L+ ++      DM   +P   +   Q+      +   + G+QC +
Sbjct: 769  FMTDVNSWLLTFGFQLHNVIPGYPKPDMDAMEPSYELIHTQMKTQEWDNSKSILGVQCEV 828

Query: 2726 EKVNDKLSDIE----FVPTPLLKMEPITRNLLPRVSYKRGVFGEGVLISRVDGRAFISVA 2781
            +K       +E       + +   +   +    + +    VFG+GV  +  DGR    + 
Sbjct: 829  QKQLKAFVTLERFDQLYGSTITSCQQAPKT--KKFASSGSVFGKGVKFALKDGRVTTDII 886

Query: 2782 DGANSVVEDVITTVFNNSYFLD-VHFSIHDQDVFYFVK----DNSLKIRDDMEELRRLSG 2836
              AN     V   + N++++L+ +HF+I   D  YFVK    +  L I       R L  
Sbjct: 887  SVANEDGRRV-AAILNHAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLSGGRRTLEN 945

Query: 2837 KFNVSQDETND--QGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAW 2894
              NV+  + N    G   R   +        +  RYG    +E+ ++L+ A +RA  +AW
Sbjct: 946  GVNVTVSQINTVLNGRTRRYTDIQLQYGALCLNTRYGTTLDEEKARVLELARQRAVRQAW 1005

Query: 2895 EREKALVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
             RE+  +  G EG  +WTE EK++++S G V G+    V S+ +YP+L+D   NI F+
Sbjct: 1006 AREQQRLREGEEGLRAWTEGEKQQVLSTGRVQGYDGFFVISVEQYPELSDSANNIHFM 1063


>M24630-1|AAA52703.1| 1625|Homo sapiens hexabrachion protein.
          Length = 1625

 Score =  180 bits (439), Expect = 5e-44
 Identities = 82/194 (42%), Positives = 107/194 (55%), Gaps = 11/194 (5%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CPN C  +G C+ G C C+ GF G DCS   CP  C Q G  +NG C C+ G+ G++C  
Sbjct: 9    CPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDC-- 66

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R  +C   DC+  G CV+G+C C  G+ G  C E+ CP+  C G G C+ G CVC +G+ 
Sbjct: 67   RDRQCP-RDCSNRGLCVDGQCVCEDGFTGPDCAELSCPN-DCHGRGRCVNGQCVCHEGFM 124

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G DC        +C  DC G G   VD Q C CH  ++G DC +  C  +C   G+CV  
Sbjct: 125  GKDCKEQ-----RCPSDCHGQGRC-VDGQ-CICHEGFTGLDCGQHSCPSDCNNLGQCVSG 177

Query: 1058 SCSCAAGWSGEFCS 1071
             C C  G+SGE CS
Sbjct: 178  RCICNEGYSGEDCS 191



 Score =  180 bits (437), Expect = 9e-44
 Identities = 83/208 (39%), Positives = 111/208 (53%), Gaps = 11/208 (5%)

Query: 901  GDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSC 960
            G+DCS+  CP  C  RG  + G+C C  G+KG +CS   D     DC+ HG CVNG C C
Sbjct: 1    GEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS---DMSCPNDCHQHGRCVNGMCVC 57

Query: 961  VRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGT 1020
              GY G+ C +  CP   CS  G C++G CVC+ G+ G DC       L C  DC G G 
Sbjct: 58   DDGYTGEDCRDRQCPRD-CSNRGLCVDGQCVCEDGFTGPDCAE-----LSCPNDCHGRGR 111

Query: 1021 FDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCA 1080
              V+ Q C CH  + G+DC ++ C  +C   GRCV   C C  G++G  C    C + C 
Sbjct: 112  C-VNGQ-CVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCN 169

Query: 1081 EHGQCKNGTCLCVSGWNGRHCTLEGCPR 1108
              GQC +G C+C  G++G  C+    P+
Sbjct: 170  NLGQCVSGRCICNEGYSGEDCSEVSPPK 197



 Score =  163 bits (396), Expect = 9e-39
 Identities = 81/208 (38%), Positives = 109/208 (52%), Gaps = 18/208 (8%)

Query: 932  GKECSLRHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTC 990
            G++CS    +   P DC+  G CV GKC C +G+KG  C ++ CP+  C  HG C+ G C
Sbjct: 1    GEDCS----QLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMC 55

Query: 991  VCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP 1050
            VC  G+ G DC    +D  QC  DCS  G   VD Q C C   ++G DC++  C  +C  
Sbjct: 56   VCDDGYTGEDC----RDR-QCPRDCSNRGLC-VDGQ-CVCEDGFTGPDCAELSCPNDCHG 108

Query: 1051 HGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSC 1110
             GRCV   C C  G+ G+ C  + C + C   G+C +G C+C  G+ G  C    CP  C
Sbjct: 109  RGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDC 168

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
               GQC     GR  C C +G+ G DC+
Sbjct: 169  NNLGQC---VSGR--CICNEGYSGEDCS 191



 Score =  149 bits (361), Expect = 2e-34
 Identities = 68/166 (40%), Positives = 91/166 (54%), Gaps = 13/166 (7%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +CPN C   G C+ G C C  G+ G+DC    CP  CS RG  ++G+C C  G+ G +C+
Sbjct: 39   SCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCA 98

Query: 937  LRHDECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKG 995
                E   P DC+G G CVNG+C C  G+ GK C E  CP   C G G C++G C+C +G
Sbjct: 99   ----ELSCPNDCHGRGRCVNGQCVCHEGFMGKDCKEQRCP-SDCHGQGRCVDGQCICHEG 153

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
            + G DCG        C  DC+  G     +  C C+  +SGEDCS+
Sbjct: 154  FTGLDCGQH-----SCPSDCNNLG--QCVSGRCICNEGYSGEDCSE 192



 Score =  109 bits (261), Expect = 2e-22
 Identities = 59/160 (36%), Positives = 77/160 (48%), Gaps = 14/160 (8%)

Query: 1005 DKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAG 1064
            D   L+C  DC   G   V+ + C C   + G DCS   C  +C  HGRCV   C C  G
Sbjct: 3    DCSQLRCPNDCHSRGRC-VEGK-CVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDG 60

Query: 1065 WSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRW 1124
            ++GE C  R C   C+  G C +G C+C  G+ G  C    CP  C G G+C V+     
Sbjct: 61   YTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGRGRC-VNG---- 115

Query: 1125 ECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
            +C C +G+ G DC   KEQ C     +D  G   C D +C
Sbjct: 116  QCVCHEGFMGKDC---KEQRC----PSDCHGQGRCVDGQC 148



 Score =  104 bits (249), Expect = 6e-21
 Identities = 52/129 (40%), Positives = 64/129 (49%), Gaps = 12/129 (9%)

Query: 1036 GEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSG 1095
            GEDCS+  C  +C   GRCV   C C  G+ G  CS   C   C +HG+C NG C+C  G
Sbjct: 1    GEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDG 60

Query: 1096 WNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG 1155
            + G  C    CPR C+  G C VD     +C C DG+ GPDC  L       S  ND  G
Sbjct: 61   YTGEDCRDRQCPRDCSNRGLC-VDG----QCVCEDGFTGPDCAEL-------SCPNDCHG 108

Query: 1156 LVDCEDPEC 1164
               C + +C
Sbjct: 109  RGRCVNGQC 117



 Score =  104 bits (249), Expect = 6e-21
 Identities = 42/99 (42%), Positives = 58/99 (58%), Gaps = 3/99 (3%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
           +CPN C G+G C+ G C C  GF G DC +  CP  C  +G  ++G+C C+ G+ G +C 
Sbjct: 101 SCPNDCHGRGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 160

Query: 937 LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP 975
            +H  C   DCN  G CV+G+C C  GY G+ C E+  P
Sbjct: 161 -QH-SCP-SDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 196



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 14/31 (45%), Positives = 22/31 (70%)

Query: 876 HNCPNGCSGKGECLMGHCQCQPGFGGDDCSK 906
           H+CP+ C+  G+C+ G C C  G+ G+DCS+
Sbjct: 162 HSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 192


>AK056531-1|BAB71206.1|  730|Homo sapiens protein ( Homo sapiens cDNA
            FLJ31969 fis, clone NT2RP7008013, highly similar to Mus
            musculus mRNA for Ten-m4. ).
          Length = 730

 Score =  177 bits (432), Expect = 4e-43
 Identities = 163/598 (27%), Positives = 279/598 (46%), Gaps = 65/598 (10%)

Query: 2396 NNAHFKYQYDGNARLSTIDVNINSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQ 2455
            N   + Y+YD + +L T+ +N    + P  R  Y+ N G+L  +S     R T  R  ++
Sbjct: 149  NTTRYSYEYDADGQLQTVSIN----DKPLWRYSYDLN-GNLHLLSPGNSARLTPLRYDIR 203

Query: 2456 DTSKQFFTIT-DYDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERI 2514
            D   +   +    D+ G ++      +  D+F    EY++   +    +   + A S  +
Sbjct: 204  DRITRLGDVQYKMDEDGFLRQ-----RGGDIF----EYNSAGLL----IKAYNRAGSWSV 250

Query: 2515 SYNYDGHLMEVVGSEDD----LKYNYDENGN---VIGIIEHGEKRY--LGYDIGDRV--- 2562
             Y YDG L   V S+      L++ Y +  N   V  +  H       L YD+   +   
Sbjct: 251  RYRYDG-LGRRVSSKSSHSHHLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAM 309

Query: 2563 -VQYGDVEFSSYDGRGF-------VGDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFD 2614
             +  GD  + + D  G         G ++K+I  + +G+I  D+NP+F + + +HGG++D
Sbjct: 310  ELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDTNPNFQIIIGYHGGLYD 369

Query: 2615 YNTNLIYLENRLYDPVVGQWMTPS---WEHLATKLSLPTDIFIYRFKNNDPINKQQNVP- 2670
              T L+++  R YD + G+W +P    W+HL++   +P ++  Y FKNN+PI+  Q++  
Sbjct: 370  PLTKLVHMGRRDYDVLAGRWTSPDHELWKHLSSSNVMPFNL--YMFKNNNPISNSQDIKC 427

Query: 2671 YMTSLNSWLQLYGYDLNKMMGSKYINDM-IFQPMTSVTAAQLAPDFGVMS----GLQCII 2725
            +MT +NSWL  +G+ L+ ++      DM   +P   +   Q+       S    G+QC +
Sbjct: 428  FMTDVNSWLLTFGFQLHNVIPGYPKPDMDAMEPSYELIHTQMKTQEWDNSKSILGVQCEV 487

Query: 2726 EKVNDKLSDIEFVPTPLLKMEPITRNL----LPRVSYKRGVFGEGVLISRVDGRAFISVA 2781
            +K       +E      L    IT  L      + +    VFG+GV  +  DGR    + 
Sbjct: 488  QKQLKAFVTLERFDQ--LYGSTITSCLQAPKTKKFASSGSVFGKGVKFALKDGRVTTDII 545

Query: 2782 DGANSVVEDVITTVFNNSYFLD-VHFSIHDQDVFYFVK----DNSLKIRDDMEELRRLSG 2836
              AN     V   + N++++L+ +HF+I   D  YFVK    +  L I       R L  
Sbjct: 546  SVANEDGRRV-AAILNHAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLSGGRRTLEN 604

Query: 2837 KFNVSQDETND--QGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAW 2894
              NV+  + N    G   R   +        +  RYG    +E+ ++L+ A +RA  +AW
Sbjct: 605  GVNVTVSQINTVLSGRTRRYTDIQLQYGALCLNTRYGTTLDEEKARVLELARQRAVRQAW 664

Query: 2895 EREKALVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
             RE+  +  G EG  +WTE EK++++S G V G+    V S+ +YP+L+D   NI F+
Sbjct: 665  AREQQRLREGEEGLRAWTEGEKQQVLSTGRVQGYDGFFVISVEQYPELSDSANNIHFM 722



 Score = 83.8 bits (198), Expect = 8e-15
 Identities = 61/227 (26%), Positives = 108/227 (47%), Gaps = 10/227 (4%)

Query: 2358 LVKNVEISDPDYDLKQDYKYHAGILKDAKMKFNSKSGLNNAHFKYQYDGNARLSTIDVNI 2417
            ++K + + +  +     Y+   G L D ++   ++ G+ NA F Y YD + R++++   I
Sbjct: 1    MLKTINLQNEGFTCTIRYR-QIGPLIDRQIFRFTEEGMVNARFDYNYDNSFRVTSMQAVI 59

Query: 2418 NSKEMPQLRLKYNQNLGSLEAVSDLRIYRNTFNRTVMQDTSKQFFTITDYDDHGRIKTFL 2477
            N   +P    +Y+   G  E      +     N+ +   T+        +D +GR+K   
Sbjct: 60   NETPLPIDLYRYDDVSGKTEQFGKFGVIYYDINQII---TTAVMTHTKHFDAYGRMKEVQ 116

Query: 2478 INIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHLMEVVGSEDDL-KY 2534
              I    ++ + ++YD   R+  K+L +G  A + R SY Y  DG L  V  ++  L +Y
Sbjct: 117  YEIFRSLMYWMTVQYDNMGRVVKKELKVGPYANTTRYSYEYDADGQLQTVSINDKPLWRY 176

Query: 2535 NYDENGNVIGIIEHGEKRY--LGYDIGDRVVQYGDVEFSSYDGRGFV 2579
            +YD NGN+  +      R   L YDI DR+ + GDV++   D  GF+
Sbjct: 177  SYDLNGNLHLLSPGNSARLTPLRYDIRDRITRLGDVQY-KMDEDGFL 222


>AK027473-1|BAB55138.1|  625|Homo sapiens protein ( Homo sapiens cDNA
            FLJ14567 fis, clone NT2RM4000386, highly similar to Mus
            musculus ODZ3 (Odz3) mRNA. ).
          Length = 625

 Score =  171 bits (417), Expect = 2e-41
 Identities = 121/387 (31%), Positives = 194/387 (50%), Gaps = 19/387 (4%)

Query: 2580 GDIVKEIKRSPFGKIIKDSNPSFYVPVDFHGGIFDYNTNLIYLENRLYDPVVGQWMTPSW 2639
            G ++K+I+ + +G+I  DSN  F + + FHGG++D  T LI+   R YD + G+W TP  
Sbjct: 236  GLMLKQIQYTAYGEIYFDSNIDFQLVIGFHGGLYDPLTKLIHFGERDYDILAGRWTTPDI 295

Query: 2640 EHLATKLSLPTDIFIYRFKNNDPINKQQNVP-YMTSLNSWLQLYGYDL-NKMMGSKYIND 2697
            E        P    +Y F+NN+P +K  +V  Y+T +NSWL  +G+ L N + G      
Sbjct: 296  EIWKRIGKDPAPFNLYMFRNNNPASKIHDVKDYITDVNSWLVTFGFHLHNAIPGFPVPKF 355

Query: 2698 MIFQPMTSVTAAQLAPDFGVMSGLQC-IIEKVNDKLSDIEFVPTPLLKMEPITRNLLPRV 2756
             + +P   +  +Q   D   + G+Q  +  +    LS  +     + +            
Sbjct: 356  DLTEPSYELVKSQQWDDIPPIFGVQQQVARQAKAFLSLGKMAEVQVSRRRAGGAQSWLWF 415

Query: 2757 SYKRGVFGEGVLISRVDGRAFISVADGANSVVEDVI--TTVFNNSYFLD-VHFSIHDQDV 2813
            +  + + G+GV+++   GR   +V + AN   ED I    V NN+++L+ +HF+I  +D 
Sbjct: 416  ATVKSLIGKGVMLAVSQGRVQTNVLNIAN---EDCIKVAAVLNNAFYLENLHFTIEGKDT 472

Query: 2814 FYFVKDNSLKIRDDMEELRRLSGK--------FNVSQDETNDQGLEVRVHAVGKGSAQAV 2865
             YF+K  + +   D+  LR  SG+          VSQ  T   G   R   V        
Sbjct: 473  HYFIKTTTPE--SDLGTLRLTSGRKALENGINVTVSQSTTVVNGRTRRFADVEMQFGALA 530

Query: 2866 IVLRYGVDPAQERIKLLKHAHKRAATRAWEREKALVAAGWEGRGSWTEEEKEELISHGIV 2925
            + +RYG+   +E+ ++L+ A +RA  RAW RE+  V  G EG   WTE EK +L+S G V
Sbjct: 531  LHVRYGMTLDEEKARILEQARQRALARAWAREQQRVRDGEEGARLWTEGEKRQLLSAGKV 590

Query: 2926 DGWAARDVHSISKYPQLADDPANIVFV 2952
             G+    V S+ +YP+LAD   NI F+
Sbjct: 591  QGYDGYYVLSVEQYPELADSANNIQFL 617



 Score = 62.5 bits (145), Expect = 2e-08
 Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 6/118 (5%)

Query: 2467 YDDHGRIKTFLINIKAFDVFRLELEYDARNRIKTKKLMIGDTAFSERISYNY--DGHLME 2524
            +D HGRIK     I    ++ + ++YD   R+  +++ IG  A + + +Y Y  DG L  
Sbjct: 7    FDAHGRIKEIQYEIFRSLMYWITIQYDNMGRVTKREIKIGPFANTTKYAYEYDVDGQLQT 66

Query: 2525 VVGSEDDL-KYNYDENGNVIGIIEHGEKRY--LGYDIGDRVVQYGDVEFSSYDGRGFV 2579
            V  +E  + +YNYD NGN+  +      R   L YD+ DR+ + GDV++   D  GF+
Sbjct: 67   VYLNEKIMWRYNYDLNGNLHLLNPSNSARLTPLRYDLRDRITRLGDVQY-RLDEDGFL 123


>AK027618-1|BAB55237.1|  849|Homo sapiens protein ( Homo sapiens cDNA
            FLJ14712 fis, clone NT2RP3000825, weakly similar to
            NEUROGENIC LOCUS NOTCH 3 PROTEIN. ).
          Length = 849

 Score =  157 bits (380), Expect = 8e-37
 Identities = 88/266 (33%), Positives = 118/266 (44%), Gaps = 20/266 (7%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYINGE-CQCNPGWKGKEC 935
            C   C    EC+  + C+C+PG+ G +C  ++C   C   G+ I    CQC PG  G  C
Sbjct: 557  CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATC 616

Query: 936  SLRHDECEVPDCNGHGHCVNGK-CSCVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCK 993
               H  C  P C   G C+ G  C+C  G+ G  C  + C +  C   G C+    C CK
Sbjct: 617  DEEH--CN-PPCQHGGICLAGNLCTCPYGFVGPRCETMVC-NRHCENGGQCLTPDICQCK 672

Query: 994  KGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGR 1053
             GW G  C T    AL C P C   G+ +    TC C   + GE C    C   C   G 
Sbjct: 673  PGWYGPTCST----AL-CDPVCLNGGSCN-KPNTCLCPNGFFGEHCQNAFCHPPCKNGGH 726

Query: 1054 CVGES-CSCAAGWSGEFCSVRLCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRSCA 1111
            C+  + C C  G++G  C   +CD  C   G+C    TC C SGW+G+ C    C + C 
Sbjct: 727  CMRNNVCVCREGYTGRRCQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCK 786

Query: 1112 GHGQCRVDNDGRWECKCFDGWDGPDC 1137
              G+C   +     C C   W+G  C
Sbjct: 787  NGGECIAPS----ICHCPSSWEGVRC 808



 Score =  147 bits (355), Expect = 8e-34
 Identities = 85/266 (31%), Positives = 113/266 (42%), Gaps = 20/266 (7%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYINGE-CQCNPGWKGKEC 935
            C   C   G+C+  + CQC PG GG  C +  C   C   G  + G  C C  G+ G  C
Sbjct: 589  CDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGICLAGNLCTCPYGFVGPRC 648

Query: 936  SLRHDECEVPDCNGHGHCVNGK-CSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCK 993
                  C    C   G C+    C C  G+ G  C    C  P C   G C +  TC+C 
Sbjct: 649  ETM--VCN-RHCENGGQCLTPDICQCKPGWYGPTCSTALCD-PVCLNGGSCNKPNTCLCP 704

Query: 994  KGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGR 1053
             G+ G  C    ++A  C P C  +G   +    C C   ++G  C K +C   C   G+
Sbjct: 705  NGFFGEHC----QNAF-CHPPCK-NGGHCMRNNVCVCREGYTGRRCQKSICDPTCMNGGK 758

Query: 1054 CVGES-CSCAAGWSGEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLEGCPRSCA 1111
            CVG S CSC +GWSG+ C+  +C  +C   G+C     C C S W G  C +  C   C 
Sbjct: 759  CVGPSTCSCPSGWSGKRCNTPICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCL 818

Query: 1112 GHGQCRVDNDGRWECKCFDGWDGPDC 1137
              G+C   N     C C   + G  C
Sbjct: 819  YGGRCIFPN----VCSCRTEYSGVKC 840



 Score =  141 bits (341), Expect = 4e-32
 Identities = 86/275 (31%), Positives = 111/275 (40%), Gaps = 26/275 (9%)

Query: 907  SVCPVLCSQRGEYINGE-CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK-CSCVRGY 964
            ++C   C +  E +    C+C PG+ G  C      C+ PDC  HG C+    C C+ G+
Sbjct: 555  TICKYPCGKSRECVAPNICKCKPGYIGSNCQTAL--CD-PDCKNHGKCIKPNICQCLPGH 611

Query: 965  KGKFCGEIDCPHPTCSGHGFCIEGT-CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDV 1023
             G  C E  C +P C   G C+ G  C C  G+ G  C TM      C   C   G   +
Sbjct: 612  GGATCDEEHC-NPPCQHGGICLAGNLCTCPYGFVGPRCETM-----VCNRHCENGGQC-L 664

Query: 1024 DTQTCSCHAKWSGEDCSKEVCSLECGPHGRC-VGESCSCAAGWSGEFCSVRLCDARCAEH 1082
                C C   W G  CS  +C   C   G C    +C C  G+ GE C    C   C   
Sbjct: 665  TPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNG 724

Query: 1083 GQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLK 1141
            G C +N  C+C  G+ GR C    C  +C   G+C     G   C C  GW G  C T  
Sbjct: 725  GHCMRNNVCVCREGYTGRRCQKSICDPTCMNGGKCV----GPSTCSCPSGWSGKRCNT-- 778

Query: 1142 EQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
              IC       K+G  +C  P  C  P+      C
Sbjct: 779  -PIC---LQKCKNG-GECIAPSICHCPSSWEGVRC 808



 Score =  123 bits (297), Expect = 9e-27
 Identities = 68/202 (33%), Positives = 92/202 (45%), Gaps = 15/202 (7%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            C   C   G+CL    CQC+PG+ G  CS ++C  +C   G       C C  G+ G+ C
Sbjct: 653  CNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHC 712

Query: 936  SLRHDECEVPDCNGHGHCV-NGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCK 993
              ++  C  P C   GHC+ N  C C  GY G+ C +  C  PTC   G C+   TC C 
Sbjct: 713  --QNAFCH-PPCKNGGHCMRNNVCVCREGYTGRRCQKSICD-PTCMNGGKCVGPSTCSCP 768

Query: 994  KGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGR 1053
             GW G  C T       CL  C   G   +    C C + W G  C   +C+ +C   GR
Sbjct: 769  SGWSGKRCNTP-----ICLQKCKNGGEC-IAPSICHCPSSWEGVRCQIPICNPKCLYGGR 822

Query: 1054 CVGES-CSCAAGWSGEFCSVRL 1074
            C+  + CSC   +SG  C  ++
Sbjct: 823  CIFPNVCSCRTEYSGVKCEKKI 844



 Score = 88.6 bits (210), Expect = 3e-16
 Identities = 74/272 (27%), Positives = 102/272 (37%), Gaps = 24/272 (8%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYK--GKFCGEIDCPHP 977
            C C PG+ G  C +    C+   C G G  ++G     C C    K   +F  +      
Sbjct: 463  CVCLPGFHGSLCEVDISGCQSNPC-GLGSYISGFHSYSCDCPPELKVETQFVNKFTTQTV 521

Query: 978  --TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWS 1035
              T S      E      +G K     T       C   C G     V    C C   + 
Sbjct: 522  VLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPC-GKSRECVAPNICKCKPGYI 580

Query: 1036 GEDCSKEVCSLECGPHGRCVGES-CSCAAGWSGEFCSVRLCDARCAEHGQCKNGT-CLCV 1093
            G +C   +C  +C  HG+C+  + C C  G  G  C    C+  C   G C  G  C C 
Sbjct: 581  GSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGICLAGNLCTCP 640

Query: 1094 SGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT-LKEQICDDSRDND 1152
             G+ G  C    C R C   GQC   +     C+C  GW GP C+T L + +C +    +
Sbjct: 641  YGFVGPRCETMVCNRHCENGGQCLTPD----ICQCKPGWYGPTCSTALCDPVCLNGGSCN 696

Query: 1153 KDGLVDCED---PECCQS----PACKSSQLCV 1177
            K     C +    E CQ+    P CK+   C+
Sbjct: 697  KPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCM 728



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 16/30 (53%), Positives = 18/30 (60%)

Query: 878 CPNGCSGKGECLMGHCQCQPGFGGDDCSKS 907
           CPN CSG G+C+   C C P F   DCS S
Sbjct: 149 CPNLCSGNGQCMEWGCACSPSFSSYDCSDS 178



 Score = 39.9 bits (89), Expect = 0.14
 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 909 CPVLCSQRGEYINGECQCNPGWKGKECSLRHDEC-EVPDCNGHGHCVNGKCSCV 961
           CP LCS  G+ +   C C+P +   +CS  +D+  E+ +    G C   K +C+
Sbjct: 149 CPNLCSGNGQCMEWGCACSPSFSSYDCSDSYDKAPEITELGNAGFCDVQKYNCM 202



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 4/77 (5%)

Query: 972  IDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCH 1031
            + CP+  CSG+G C+E  C C   +   DC     D    + +    G  DV    C   
Sbjct: 147  LKCPN-LCSGNGQCMEWGCACSPSFSSYDCSD-SYDKAPEITELGNAGFCDVQKYNCMM- 203

Query: 1032 AKWSGEDCSKEVCSLEC 1048
             +  G+   KE+ S++C
Sbjct: 204  VRVFGKG-FKELPSIKC 219


>Z94057-1|CAI21650.1| 1358|Homo sapiens tenascin R (restrictin,
            janusin) protein.
          Length = 1358

 Score =  137 bits (332), Expect = 5e-31
 Identities = 58/127 (45%), Positives = 76/127 (59%), Gaps = 4/127 (3%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP GCS +G C+ G C C   + GDDCS+  CP  CS RG  ++GEC C   + G++C  
Sbjct: 204  CPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDC-- 261

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC+G G C NG C C  GY G+ CG+  C +  CSG G C EG CVC++G++
Sbjct: 262  RELRCP-GDCSGKGRCANGTCLCEEGYVGEDCGQRQCLN-ACSGRGQCEEGLCVCEEGYQ 319

Query: 998  GADCGTM 1004
            G DC  +
Sbjct: 320  GPDCSAV 326



 Score =  131 bits (317), Expect = 3e-29
 Identities = 68/174 (39%), Positives = 91/174 (52%), Gaps = 17/174 (9%)

Query: 970  GEID-CPHPTCSGHG-FCIEGT-CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ 1026
            G++D  PH  CSGHG F  E   C+C +GW G +C         C   CS  G   VD Q
Sbjct: 167  GQLDYIPH--CSGHGNFSFESCGCICNEGWFGKNCSEP-----YCPLGCSSRGVC-VDGQ 218

Query: 1027 TCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCK 1086
             C C +++SG+DCS+  C  +C   G CV   C C   ++GE C    C   C+  G+C 
Sbjct: 219  -CICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCA 277

Query: 1087 NGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
            NGTCLC  G+ G  C    C  +C+G GQC    +G   C C +G+ GPDC+ +
Sbjct: 278  NGTCLCEEGYVGEDCGQRQCLNACSGRGQCE---EGL--CVCEEGYQGPDCSAV 326



 Score =  131 bits (317), Expect = 3e-29
 Identities = 62/166 (37%), Positives = 84/166 (50%), Gaps = 10/166 (6%)

Query: 944  VPDCNGHGHCVNGKCSCV--RGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADC 1001
            +P C+GHG+     C C+   G+ GK C E  CP   CS  G C++G C+C   + G DC
Sbjct: 172  IPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLG-CSSRGVCVDGQCICDSEYSGDDC 230

Query: 1002 GTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSC 1061
                   L+C  DCS  G   VD + C C   ++GEDC +  C  +C   GRC   +C C
Sbjct: 231  SE-----LRCPTDCSSRGLC-VDGE-CVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLC 283

Query: 1062 AAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCP 1107
              G+ GE C  R C   C+  GQC+ G C+C  G+ G  C+    P
Sbjct: 284  EEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPP 329



 Score =  130 bits (313), Expect = 1e-28
 Identities = 65/162 (40%), Positives = 86/162 (53%), Gaps = 15/162 (9%)

Query: 882  CSGKGECLMGHCQC--QPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH 939
            CSG G      C C    G+ G +CS+  CP+ CS RG  ++G+C C+  + G +CS   
Sbjct: 175  CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCS--- 231

Query: 940  DECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKG 998
             E   P DC+  G CV+G+C C   Y G+ C E+ CP   CSG G C  GTC+C++G+ G
Sbjct: 232  -ELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCP-GDCSGKGRCANGTCLCEEGYVG 289

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS 1040
             DCG       QCL  CSG G    +   C C   + G DCS
Sbjct: 290  EDCGQR-----QCLNACSGRG--QCEEGLCVCEEGYQGPDCS 324



 Score =  118 bits (284), Expect = 3e-25
 Identities = 56/164 (34%), Positives = 78/164 (47%), Gaps = 7/164 (4%)

Query: 1009 LQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE 1068
            L  +P CSGHG F  ++  C C+  W G++CS+  C L C   G CV   C C + +SG+
Sbjct: 169  LDYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGD 228

Query: 1069 FCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKC 1128
             CS   C   C+  G C +G C+C   + G  C    CP  C+G G+C         C C
Sbjct: 229  DCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRC-----ANGTCLC 283

Query: 1129 FDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKS 1172
             +G+ G DC   +       R   ++GL  CE  E  Q P C +
Sbjct: 284  EEGYVGEDCGQRQCLNACSGRGQCEEGLCVCE--EGYQGPDCSA 325



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 1/33 (3%)

Query: 878 CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP 910
           C N CSG+G+C  G C C+ G+ G DCS +V P
Sbjct: 297 CLNACSGRGQCEEGLCVCEEGYQGPDCS-AVAP 328


>Z94055-1|CAI19943.1| 1358|Homo sapiens tenascin R (restrictin,
            janusin) protein.
          Length = 1358

 Score =  137 bits (332), Expect = 5e-31
 Identities = 58/127 (45%), Positives = 76/127 (59%), Gaps = 4/127 (3%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP GCS +G C+ G C C   + GDDCS+  CP  CS RG  ++GEC C   + G++C  
Sbjct: 204  CPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDC-- 261

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC+G G C NG C C  GY G+ CG+  C +  CSG G C EG CVC++G++
Sbjct: 262  RELRCP-GDCSGKGRCANGTCLCEEGYVGEDCGQRQCLN-ACSGRGQCEEGLCVCEEGYQ 319

Query: 998  GADCGTM 1004
            G DC  +
Sbjct: 320  GPDCSAV 326



 Score =  131 bits (317), Expect = 3e-29
 Identities = 68/174 (39%), Positives = 91/174 (52%), Gaps = 17/174 (9%)

Query: 970  GEID-CPHPTCSGHG-FCIEGT-CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ 1026
            G++D  PH  CSGHG F  E   C+C +GW G +C         C   CS  G   VD Q
Sbjct: 167  GQLDYIPH--CSGHGNFSFESCGCICNEGWFGKNCSEP-----YCPLGCSSRGVC-VDGQ 218

Query: 1027 TCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCK 1086
             C C +++SG+DCS+  C  +C   G CV   C C   ++GE C    C   C+  G+C 
Sbjct: 219  -CICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCA 277

Query: 1087 NGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
            NGTCLC  G+ G  C    C  +C+G GQC    +G   C C +G+ GPDC+ +
Sbjct: 278  NGTCLCEEGYVGEDCGQRQCLNACSGRGQCE---EGL--CVCEEGYQGPDCSAV 326



 Score =  131 bits (317), Expect = 3e-29
 Identities = 62/166 (37%), Positives = 84/166 (50%), Gaps = 10/166 (6%)

Query: 944  VPDCNGHGHCVNGKCSCV--RGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADC 1001
            +P C+GHG+     C C+   G+ GK C E  CP   CS  G C++G C+C   + G DC
Sbjct: 172  IPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLG-CSSRGVCVDGQCICDSEYSGDDC 230

Query: 1002 GTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSC 1061
                   L+C  DCS  G   VD + C C   ++GEDC +  C  +C   GRC   +C C
Sbjct: 231  SE-----LRCPTDCSSRGLC-VDGE-CVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLC 283

Query: 1062 AAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCP 1107
              G+ GE C  R C   C+  GQC+ G C+C  G+ G  C+    P
Sbjct: 284  EEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPP 329



 Score =  130 bits (313), Expect = 1e-28
 Identities = 65/162 (40%), Positives = 86/162 (53%), Gaps = 15/162 (9%)

Query: 882  CSGKGECLMGHCQC--QPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH 939
            CSG G      C C    G+ G +CS+  CP+ CS RG  ++G+C C+  + G +CS   
Sbjct: 175  CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCS--- 231

Query: 940  DECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKG 998
             E   P DC+  G CV+G+C C   Y G+ C E+ CP   CSG G C  GTC+C++G+ G
Sbjct: 232  -ELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCP-GDCSGKGRCANGTCLCEEGYVG 289

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS 1040
             DCG       QCL  CSG G    +   C C   + G DCS
Sbjct: 290  EDCGQR-----QCLNACSGRG--QCEEGLCVCEEGYQGPDCS 324



 Score =  118 bits (284), Expect = 3e-25
 Identities = 56/164 (34%), Positives = 78/164 (47%), Gaps = 7/164 (4%)

Query: 1009 LQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE 1068
            L  +P CSGHG F  ++  C C+  W G++CS+  C L C   G CV   C C + +SG+
Sbjct: 169  LDYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGD 228

Query: 1069 FCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKC 1128
             CS   C   C+  G C +G C+C   + G  C    CP  C+G G+C         C C
Sbjct: 229  DCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRC-----ANGTCLC 283

Query: 1129 FDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKS 1172
             +G+ G DC   +       R   ++GL  CE  E  Q P C +
Sbjct: 284  EEGYVGEDCGQRQCLNACSGRGQCEEGLCVCE--EGYQGPDCSA 325



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 1/33 (3%)

Query: 878 CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP 910
           C N CSG+G+C  G C C+ G+ G DCS +V P
Sbjct: 297 CLNACSGRGQCEEGLCVCEEGYQGPDCS-AVAP 328


>Z67996-1|CAA91947.1| 1358|Homo sapiens tenascin-R (restrictin)
            protein.
          Length = 1358

 Score =  137 bits (332), Expect = 5e-31
 Identities = 58/127 (45%), Positives = 76/127 (59%), Gaps = 4/127 (3%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP GCS +G C+ G C C   + GDDCS+  CP  CS RG  ++GEC C   + G++C  
Sbjct: 204  CPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDC-- 261

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC+G G C NG C C  GY G+ CG+  C +  CSG G C EG CVC++G++
Sbjct: 262  RELRCP-GDCSGKGRCANGTCLCEEGYVGEDCGQRQCLN-ACSGRGQCEEGLCVCEEGYQ 319

Query: 998  GADCGTM 1004
            G DC  +
Sbjct: 320  GPDCSAV 326



 Score =  131 bits (317), Expect = 3e-29
 Identities = 68/174 (39%), Positives = 91/174 (52%), Gaps = 17/174 (9%)

Query: 970  GEID-CPHPTCSGHG-FCIEGT-CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ 1026
            G++D  PH  CSGHG F  E   C+C +GW G +C         C   CS  G   VD Q
Sbjct: 167  GQLDYIPH--CSGHGNFSFESCGCICNEGWFGKNCSEP-----YCPLGCSSRGVC-VDGQ 218

Query: 1027 TCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCK 1086
             C C +++SG+DCS+  C  +C   G CV   C C   ++GE C    C   C+  G+C 
Sbjct: 219  -CICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCA 277

Query: 1087 NGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
            NGTCLC  G+ G  C    C  +C+G GQC    +G   C C +G+ GPDC+ +
Sbjct: 278  NGTCLCEEGYVGEDCGQRQCLNACSGRGQCE---EGL--CVCEEGYQGPDCSAV 326



 Score =  131 bits (317), Expect = 3e-29
 Identities = 62/166 (37%), Positives = 84/166 (50%), Gaps = 10/166 (6%)

Query: 944  VPDCNGHGHCVNGKCSCV--RGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADC 1001
            +P C+GHG+     C C+   G+ GK C E  CP   CS  G C++G C+C   + G DC
Sbjct: 172  IPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLG-CSSRGVCVDGQCICDSEYSGDDC 230

Query: 1002 GTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSC 1061
                   L+C  DCS  G   VD + C C   ++GEDC +  C  +C   GRC   +C C
Sbjct: 231  SE-----LRCPTDCSSRGLC-VDGE-CVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLC 283

Query: 1062 AAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCP 1107
              G+ GE C  R C   C+  GQC+ G C+C  G+ G  C+    P
Sbjct: 284  EEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPP 329



 Score =  130 bits (313), Expect = 1e-28
 Identities = 65/162 (40%), Positives = 86/162 (53%), Gaps = 15/162 (9%)

Query: 882  CSGKGECLMGHCQC--QPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH 939
            CSG G      C C    G+ G +CS+  CP+ CS RG  ++G+C C+  + G +CS   
Sbjct: 175  CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCS--- 231

Query: 940  DECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKG 998
             E   P DC+  G CV+G+C C   Y G+ C E+ CP   CSG G C  GTC+C++G+ G
Sbjct: 232  -ELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCP-GDCSGKGRCANGTCLCEEGYVG 289

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS 1040
             DCG       QCL  CSG G    +   C C   + G DCS
Sbjct: 290  EDCGQR-----QCLNACSGRG--QCEEGLCVCEEGYQGPDCS 324



 Score =  118 bits (284), Expect = 3e-25
 Identities = 56/164 (34%), Positives = 78/164 (47%), Gaps = 7/164 (4%)

Query: 1009 LQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE 1068
            L  +P CSGHG F  ++  C C+  W G++CS+  C L C   G CV   C C + +SG+
Sbjct: 169  LDYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGD 228

Query: 1069 FCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKC 1128
             CS   C   C+  G C +G C+C   + G  C    CP  C+G G+C         C C
Sbjct: 229  DCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRC-----ANGTCLC 283

Query: 1129 FDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKS 1172
             +G+ G DC   +       R   ++GL  CE  E  Q P C +
Sbjct: 284  EEGYVGEDCGQRQCLNACSGRGQCEEGLCVCE--EGYQGPDCSA 325



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 1/33 (3%)

Query: 878 CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP 910
           C N CSG+G+C  G C C+ G+ G DCS +V P
Sbjct: 297 CLNACSGRGQCEEGLCVCEEGYQGPDCS-AVAP 328


>X98085-1|CAA66709.1| 1358|Homo sapiens tenascin-R protein.
          Length = 1358

 Score =  137 bits (332), Expect = 5e-31
 Identities = 58/127 (45%), Positives = 76/127 (59%), Gaps = 4/127 (3%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP GCS +G C+ G C C   + GDDCS+  CP  CS RG  ++GEC C   + G++C  
Sbjct: 204  CPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDC-- 261

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC+G G C NG C C  GY G+ CG+  C +  CSG G C EG CVC++G++
Sbjct: 262  RELRCP-GDCSGKGRCANGTCLCEEGYVGEDCGQRQCLN-ACSGRGQCEEGLCVCEEGYQ 319

Query: 998  GADCGTM 1004
            G DC  +
Sbjct: 320  GPDCSAV 326



 Score =  131 bits (317), Expect = 3e-29
 Identities = 68/174 (39%), Positives = 91/174 (52%), Gaps = 17/174 (9%)

Query: 970  GEID-CPHPTCSGHG-FCIEGT-CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ 1026
            G++D  PH  CSGHG F  E   C+C +GW G +C         C   CS  G   VD Q
Sbjct: 167  GQLDYIPH--CSGHGNFSFESCGCICNEGWFGKNCSEP-----YCPLGCSSRGVC-VDGQ 218

Query: 1027 TCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCK 1086
             C C +++SG+DCS+  C  +C   G CV   C C   ++GE C    C   C+  G+C 
Sbjct: 219  -CICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCA 277

Query: 1087 NGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
            NGTCLC  G+ G  C    C  +C+G GQC    +G   C C +G+ GPDC+ +
Sbjct: 278  NGTCLCEEGYVGEDCGQRQCLNACSGRGQCE---EGL--CVCEEGYQGPDCSAV 326



 Score =  131 bits (317), Expect = 3e-29
 Identities = 62/166 (37%), Positives = 84/166 (50%), Gaps = 10/166 (6%)

Query: 944  VPDCNGHGHCVNGKCSCV--RGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADC 1001
            +P C+GHG+     C C+   G+ GK C E  CP   CS  G C++G C+C   + G DC
Sbjct: 172  IPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLG-CSSRGVCVDGQCICDSEYSGDDC 230

Query: 1002 GTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSC 1061
                   L+C  DCS  G   VD + C C   ++GEDC +  C  +C   GRC   +C C
Sbjct: 231  SE-----LRCPTDCSSRGLC-VDGE-CVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLC 283

Query: 1062 AAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCP 1107
              G+ GE C  R C   C+  GQC+ G C+C  G+ G  C+    P
Sbjct: 284  EEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPP 329



 Score =  130 bits (313), Expect = 1e-28
 Identities = 65/162 (40%), Positives = 86/162 (53%), Gaps = 15/162 (9%)

Query: 882  CSGKGECLMGHCQC--QPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH 939
            CSG G      C C    G+ G +CS+  CP+ CS RG  ++G+C C+  + G +CS   
Sbjct: 175  CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCS--- 231

Query: 940  DECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKG 998
             E   P DC+  G CV+G+C C   Y G+ C E+ CP   CSG G C  GTC+C++G+ G
Sbjct: 232  -ELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCP-GDCSGKGRCANGTCLCEEGYVG 289

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS 1040
             DCG       QCL  CSG G    +   C C   + G DCS
Sbjct: 290  EDCGQR-----QCLNACSGRG--QCEEGLCVCEEGYQGPDCS 324



 Score =  118 bits (284), Expect = 3e-25
 Identities = 56/164 (34%), Positives = 78/164 (47%), Gaps = 7/164 (4%)

Query: 1009 LQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE 1068
            L  +P CSGHG F  ++  C C+  W G++CS+  C L C   G CV   C C + +SG+
Sbjct: 169  LDYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGD 228

Query: 1069 FCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKC 1128
             CS   C   C+  G C +G C+C   + G  C    CP  C+G G+C         C C
Sbjct: 229  DCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRC-----ANGTCLC 283

Query: 1129 FDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKS 1172
             +G+ G DC   +       R   ++GL  CE  E  Q P C +
Sbjct: 284  EEGYVGEDCGQRQCLNACSGRGQCEEGLCVCE--EGYQGPDCSA 325



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 1/33 (3%)

Query: 878 CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP 910
           C N CSG+G+C  G C C+ G+ G DCS +V P
Sbjct: 297 CLNACSGRGQCEEGLCVCEEGYQGPDCS-AVAP 328


>BC129830-1|AAI29831.1| 1257|Homo sapiens TNR protein protein.
          Length = 1257

 Score =  137 bits (332), Expect = 5e-31
 Identities = 58/127 (45%), Positives = 76/127 (59%), Gaps = 4/127 (3%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP GCS +G C+ G C C   + GDDCS+  CP  CS RG  ++GEC C   + G++C  
Sbjct: 103  CPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDC-- 160

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
            R   C   DC+G G C NG C C  GY G+ CG+  C +  CSG G C EG CVC++G++
Sbjct: 161  RELRCP-GDCSGKGRCANGTCLCEEGYVGEDCGQRQCLN-ACSGRGQCEEGLCVCEEGYQ 218

Query: 998  GADCGTM 1004
            G DC  +
Sbjct: 219  GPDCSAV 225



 Score =  131 bits (317), Expect = 3e-29
 Identities = 68/174 (39%), Positives = 91/174 (52%), Gaps = 17/174 (9%)

Query: 970  GEID-CPHPTCSGHG-FCIEGT-CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ 1026
            G++D  PH  CSGHG F  E   C+C +GW G +C         C   CS  G   VD Q
Sbjct: 66   GQLDYIPH--CSGHGNFSFESCGCICNEGWFGKNCSEP-----YCPLGCSSRGVC-VDGQ 117

Query: 1027 TCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCK 1086
             C C +++SG+DCS+  C  +C   G CV   C C   ++GE C    C   C+  G+C 
Sbjct: 118  -CICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCA 176

Query: 1087 NGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
            NGTCLC  G+ G  C    C  +C+G GQC    +G   C C +G+ GPDC+ +
Sbjct: 177  NGTCLCEEGYVGEDCGQRQCLNACSGRGQCE---EGL--CVCEEGYQGPDCSAV 225



 Score =  131 bits (317), Expect = 3e-29
 Identities = 62/166 (37%), Positives = 84/166 (50%), Gaps = 10/166 (6%)

Query: 944  VPDCNGHGHCVNGKCSCV--RGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADC 1001
            +P C+GHG+     C C+   G+ GK C E  CP   CS  G C++G C+C   + G DC
Sbjct: 71   IPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLG-CSSRGVCVDGQCICDSEYSGDDC 129

Query: 1002 GTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSC 1061
                   L+C  DCS  G   VD + C C   ++GEDC +  C  +C   GRC   +C C
Sbjct: 130  SE-----LRCPTDCSSRGLC-VDGE-CVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLC 182

Query: 1062 AAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCP 1107
              G+ GE C  R C   C+  GQC+ G C+C  G+ G  C+    P
Sbjct: 183  EEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPP 228



 Score =  130 bits (313), Expect = 1e-28
 Identities = 65/162 (40%), Positives = 86/162 (53%), Gaps = 15/162 (9%)

Query: 882  CSGKGECLMGHCQC--QPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH 939
            CSG G      C C    G+ G +CS+  CP+ CS RG  ++G+C C+  + G +CS   
Sbjct: 74   CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCS--- 130

Query: 940  DECEVP-DCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKG 998
             E   P DC+  G CV+G+C C   Y G+ C E+ CP   CSG G C  GTC+C++G+ G
Sbjct: 131  -ELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCP-GDCSGKGRCANGTCLCEEGYVG 188

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS 1040
             DCG       QCL  CSG G    +   C C   + G DCS
Sbjct: 189  EDCGQR-----QCLNACSGRG--QCEEGLCVCEEGYQGPDCS 223



 Score =  118 bits (284), Expect = 3e-25
 Identities = 56/164 (34%), Positives = 78/164 (47%), Gaps = 7/164 (4%)

Query: 1009 LQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE 1068
            L  +P CSGHG F  ++  C C+  W G++CS+  C L C   G CV   C C + +SG+
Sbjct: 68   LDYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGD 127

Query: 1069 FCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKC 1128
             CS   C   C+  G C +G C+C   + G  C    CP  C+G G+C         C C
Sbjct: 128  DCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRC-----ANGTCLC 182

Query: 1129 FDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKS 1172
             +G+ G DC   +       R   ++GL  CE  E  Q P C +
Sbjct: 183  EEGYVGEDCGQRQCLNACSGRGQCEEGLCVCE--EGYQGPDCSA 224



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 1/33 (3%)

Query: 878 CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP 910
           C N CSG+G+C  G C C+ G+ G DCS +V P
Sbjct: 196 CLNACSGRGQCEEGLCVCEEGYQGPDCS-AVAP 227


>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
            protein.
          Length = 2471

 Score =  134 bits (323), Expect = 6e-30
 Identities = 94/301 (31%), Positives = 131/301 (43%), Gaps = 47/301 (15%)

Query: 880  NGCSGKGEC---LMGH-CQCQPGFGGDDCSKSVCP---------VLCSQRGEYINGECQC 926
            N C  +G C   + G+ C C   + G +C   + P          +C +   + +  C C
Sbjct: 802  NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLC 861

Query: 927  NPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGE--IDCPHPTCS 980
             PGW+G+ C++  DEC    C  HG C N +    C C  G+ G  C E   DC    C 
Sbjct: 862  APGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQ 921

Query: 981  GHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD--VDTQTCSCHAK 1033
              G C++G    +C+C  G+ G  C T   D  +CL + C   GT    V++ TC C A 
Sbjct: 922  NGGSCMDGVNTFSCLCLPGFTGDKCQT---DMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978

Query: 1034 WSGEDCSKEV--CS-LECGPHGRCV----GESCSCAAGWSGEFC--SVRLCDAR-CAEHG 1083
            + G  C   +  C+   C   G CV      SC C  G++G FC   +  C +  C   G
Sbjct: 979  FDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEG 1038

Query: 1084 QCKNG----TCLCVSGWNGRHC-TLEG-CPRS-CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
             C +G     C C  G+ G++C TL   C RS C   G C V      +C C  GW G  
Sbjct: 1039 TCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC-VQKKAESQCLCPSGWAGAY 1097

Query: 1137 C 1137
            C
Sbjct: 1098 C 1098



 Score =  124 bits (298), Expect = 6e-27
 Identities = 95/322 (29%), Positives = 132/322 (40%), Gaps = 45/322 (13%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
            ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 149  LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 208

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGE--IDCPHPT 978
            C  G+ G+ C   +  C    C   G C        +C+C+ G++G  C     DCP+  
Sbjct: 209  CPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR 268

Query: 979  CSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDT--QTCSCH 1031
            C   G C++G     C C   W G  C T D D     P+ C   GT         C C 
Sbjct: 269  CQNGGVCVDGVNTYNCRCPPQWTGQFC-TEDVDECLLQPNACQNGGTCANRNGGYGCVCV 327

Query: 1032 AKWSGEDCSKEV--CSL-ECGPHGRCVGE----SCSCAAGWSGEFCSV-RLCDAR-CAEH 1082
              WSG+DCS+ +  C+   C P   C+      SC C  G +G  C +   C +  C + 
Sbjct: 328  NGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKG 387

Query: 1083 GQCK----NG--TCLCVSGWNGRHCT--LEGCPRS----CAGHGQCRVDNDGRWECKCFD 1130
              C     NG   C C  G+ G  CT  ++ C  +    C   G+C V+ DG + C+C  
Sbjct: 388  ALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKC-VNTDGAFHCECLK 446

Query: 1131 GWDGPDCTTLKEQICDDSRDND 1152
            G+ GP C     +   D   ND
Sbjct: 447  GYAGPRCEMDINECHSDPCQND 468



 Score =  119 bits (287), Expect = 1e-25
 Identities = 94/329 (28%), Positives = 135/329 (41%), Gaps = 48/329 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVL---CSQRGEYING----ECQCNPGWKGKECSLRHDECEVP 945
            C+C PGF G DC + +   L   C   G  ++G     C C PG+ G +C    +EC   
Sbjct: 897  CECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSE 956

Query: 946  DCNGHGHC---VNG-KCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEG----TCVCKKG 995
             C   G C   VN   C C  G+ G  C     +C   +C   G C++G    +C+C  G
Sbjct: 957  PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGP 1050
            + G+ C   + +     P C   GT    + T  CSC   ++G++C   V  CS   C  
Sbjct: 1017 FTGSFC-LHEINECSSHP-CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKN 1074

Query: 1051 HGRCV---GES-CSCAAGWSGEFCSVR--LCDAR-----------CAEHGQCKNG----T 1089
             G CV    ES C C +GW+G +C V    CD             C   G C N      
Sbjct: 1075 KGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY 1134

Query: 1090 CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDD 1147
            C C  G+ G +C   L+ C  +   HG    D  G + C+C  G+ G +C    ++ C +
Sbjct: 1135 CQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDE-CQN 1193

Query: 1148 SRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                +    +D  +   C  P      LC
Sbjct: 1194 QPCQNGGTCIDLVNHFKCSCPPGTRGLLC 1222



 Score =  117 bits (281), Expect = 7e-25
 Identities = 86/296 (29%), Positives = 127/296 (42%), Gaps = 41/296 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNP 928
            N C   G+C+      HC+C  G+ G  C   +  C     Q      + I G  C C P
Sbjct: 425  NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP 484

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EI-DCPHPTCSGH 982
            G+KG  C L  +EC+   C  +G CV+     +C C  G+ G  C  +I DC    C   
Sbjct: 485  GFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNG 544

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSG 1036
              CI+      C C  G+ G  C   +++   C PD   HG     +D+ TC C+  + G
Sbjct: 545  AKCIDHPNGYECQCATGFTGVLC---EENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMG 601

Query: 1037 EDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDARCAEHGQCKN 1087
              CS ++  C S  C   GRC+    G  C+C  G SG  C +    C +    HG C +
Sbjct: 602  AICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMD 661

Query: 1088 G----TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G    +C+C  G+ G+ C   ++ C  +    G   ++    + C C +G   P C
Sbjct: 662  GINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSC 717



 Score =  111 bits (266), Expect = 5e-23
 Identities = 92/339 (27%), Positives = 137/339 (40%), Gaps = 48/339 (14%)

Query: 893  CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
            C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 131  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 190

Query: 947  -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEG-----TCVCKK 994
             C   G C+N     +C C +G+ G++C    + C    C   G C +       C C  
Sbjct: 191  HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 250

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV--CSLE---CG 1049
            G++G+ C     D         G     V+T  C C  +W+G+ C+++V  C L+   C 
Sbjct: 251  GFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310

Query: 1050 PHGRCV----GESCSCAAGWSGEFCSVRLCD---ARCAEHGQC----KNGTCLCVSGWNG 1098
              G C     G  C C  GWSG+ CS  + D   A C     C     + +C+C  G  G
Sbjct: 311  NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370

Query: 1099 RHCTLEGCPRSCAGHGQCRVDN---DGRWECKCFDGWDGPDCTTLKEQICDDSRDN---- 1151
              C L+    S   H     D    +G++ C C  G+ G DCT   ++ C  +  N    
Sbjct: 371  LLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDE-CAMANSNPCEH 429

Query: 1152 -----DKDGLVDCEDPECCQSPACKSS-QLCVSSPKPTD 1184
                 + DG   CE  +    P C+     C S P   D
Sbjct: 430  AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468



 Score =  107 bits (257), Expect = 6e-22
 Identities = 95/340 (27%), Positives = 129/340 (37%), Gaps = 47/340 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVLCSQ--RGEYING----ECQCNPG 929
            N C     C+ G     C C  G     C   V   L +    G    G    +C C+ G
Sbjct: 689  NPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAG 748

Query: 930  WKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCG-EID-CPHPTCSGHG 983
            W G  C +  +EC    C   G C   VNG +C+C +G+KG  C   ID C    C   G
Sbjct: 749  WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQG 808

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF----DVDTQTCSCHAKW 1034
             C +     TC C   + G +C T+      C P+ C          + ++ TC C   W
Sbjct: 809  TCFDDISGYTCHCVLPYTGKNCQTV---LAPCSPNPCENAAVCKESPNFESYTCLCAPGW 865

Query: 1035 SGEDCS---KEVCSLECGPHGRCVGES----CSCAAGWSGEFCSVRLCDA---RCAEHGQ 1084
             G+ C+    E  S  C  HG C        C C  G+SG  C   + D     C   G 
Sbjct: 866  QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGS 925

Query: 1085 CKNG----TCLCVSGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C +G    +CLC+ G+ G  C     E     C   G C  D    + CKC  G+DG  C
Sbjct: 926  CMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCS-DYVNSYTCKCQAGFDGVHC 984

Query: 1138 TTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
                 + C +S   +    VD  +   C  P   +   C+
Sbjct: 985  ENNINE-CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCL 1023



 Score =  105 bits (252), Expect = 2e-21
 Identities = 97/341 (28%), Positives = 135/341 (39%), Gaps = 62/341 (18%)

Query: 882  CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGW 930
            C   G C+      +CQC  G+ G  C + +  C     Q G    ++I G  C+C PG+
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179

Query: 931  KGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDCPH-PTCSGHG 983
            +G  C    DEC+   C   G C+    + KCSC  G +G  C E   DC   P C   G
Sbjct: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGG 1239

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD----VDTQTCSCHAKW 1034
             C++     +C C  G+ G  C   + D  +CL + CS  G+ D     +   C C + +
Sbjct: 1240 QCMDRIGGYSCRCLPGFAGERC---EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296

Query: 1035 SGEDCSK--EVC-SLECGPHGRCV-------GESCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            +G  C    +VC  + C   G C        G  C C  G+SG  C       +C +  Q
Sbjct: 1297 TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQ 1356

Query: 1085 C----KNGTCLCVSGWNGRHCTLEGCPRS-CAGHGQCRVDND-GRWECKC---FDG---- 1131
            C        C C S    R C   GC  S C   G C        + C+C   F G    
Sbjct: 1357 CVHTASGPRCFCPS---PRDCE-SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412

Query: 1132 -WDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACK 1171
             +  P  T     +     D  +DG+ D    E C S AC+
Sbjct: 1413 LYTAPPSTPPATCLSQYCADKARDGVCD----EACNSHACQ 1449



 Score =  101 bits (243), Expect = 3e-20
 Identities = 74/262 (28%), Positives = 104/262 (39%), Gaps = 33/262 (12%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKK 994
            C   G CV      G C C  G+ G++C   D C    C   G C+      + TC C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECG 1049
            G+ G DC             C   GT  +   DT  C+C   ++G++C   + C S  C 
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 1050 PHGRCVGE----SCSCAAGWSGEFC--SVRLCD--ARCAEHGQCKN--GT--CLCVSGWN 1097
                C       SC C  G++G+ C   V  CD    C   G C N  G+  C C  G+ 
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214

Query: 1098 GRHCT---LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKD 1154
            G++C    +   P  C   G CR   D  +EC C  G++G  C    +  C + R  +  
Sbjct: 215  GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDD-CPNHRCQNGG 273

Query: 1155 GLVDCEDPECCQSPACKSSQLC 1176
              VD  +   C+ P   + Q C
Sbjct: 274  VCVDGVNTYNCRCPPQWTGQFC 295



 Score = 98.7 bits (235), Expect = 3e-19
 Identities = 92/353 (26%), Positives = 135/353 (38%), Gaps = 58/353 (16%)

Query: 882  CSGKGECLM-----GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNP 928
            C  +G C+      G+C+C  GF G      D C K+ C     C  +       C+C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 929  GWKGKEC--SLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCS 980
            G+ G++C  S  H       C   G C        +C+C  G+ GK C   D C    C+
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 981  GHGFCI----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHA 1032
                C     + +C C  G+ G  C T   D  +C +P    HG   ++   +  C C  
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCPQ 211

Query: 1033 KWSGEDCSK---EVCSLECGPHGRC--VGE---SCSCAAGWSGEFCSVRLCDA---RCAE 1081
             ++G+ C           C   G C   G+    C+C  G+ G  C   + D    RC  
Sbjct: 212  GFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQN 271

Query: 1082 HGQCKNG----TCLCVSGWNGRHCT--LEGC---PRSCAGHGQCRVDNDGRWECKCFDGW 1132
             G C +G     C C   W G+ CT  ++ C   P +C   G C  + +G + C C +GW
Sbjct: 272  GGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC-ANRNGGYGCVCVNGW 330

Query: 1133 DGPDCTTLKEQIC-----DDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSP 1180
             G DC+   +          S   D+     C  PE      C     C+S+P
Sbjct: 331  SGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383



 Score = 97.1 bits (231), Expect = 9e-19
 Identities = 88/309 (28%), Positives = 125/309 (40%), Gaps = 53/309 (17%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 71   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 129

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 130  ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVD---TQ 1026
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT       T 
Sbjct: 189  P-GHCQHGGTCLNLPGSYQCQCPQGFTGQYC---DSLYVPCAPSPCVNGGTCRQTGDFTF 244

Query: 1027 TCSCHAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLC-- 1075
             C+C   + G  C + +  C +  C   G CV      +C C   W+G+FC+  V  C  
Sbjct: 245  ECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLL 304

Query: 1076 -DARCAEHGQC--KNG--TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKC 1128
                C   G C  +NG   C+CV+GW+G  C+  ++ C  +    G   +D    + C C
Sbjct: 305  QPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMC 364

Query: 1129 FDGWDGPDC 1137
             +G  G  C
Sbjct: 365  PEGKAGLLC 373



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 88/314 (28%), Positives = 125/314 (39%), Gaps = 61/314 (19%)

Query: 878  CPNGCSG-KGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C  G +G K +  M  C  +P   G  CS            +Y+N   C+C  G+ G  C
Sbjct: 937  CLPGFTGDKCQTDMNECLSEPCKNGGTCS------------DYVNSYTCKCQAGFDGVHC 984

Query: 936  SLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI-DCPHPTCSGHGFCIEG- 988
                +EC    C   G CV+G     C C  G+ G FC  EI +C    C   G C++G 
Sbjct: 985  ENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF---DVDTQTCSCHAKWSGEDCSKE 1042
                C C  G+ G +C T+    L     C   GT      ++Q C C + W+G  C   
Sbjct: 1045 GTYRCSCPLGYTGKNCQTLVN--LCSRSPCKNKGTCVQKKAESQ-CLCPSGWAGAYCDVP 1101

Query: 1043 VCSLE-------------CGPHGRCVGES----CSCAAGWSGEFCSVRL--CDARCAEHG 1083
              S +             C   G C+       C C  G++G +C  +L  C +   +HG
Sbjct: 1102 NVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHG 1161

Query: 1084 -QCKN----GTCLCVSGWNGRHCTLE--GCP-RSCAGHGQCRVDNDGRWECKCFDGWDGP 1135
              C +      C CV G+ G +C  E   C  + C   G C +D    ++C C  G  G 
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC-IDLVNHFKCSCPPGTRGL 1220

Query: 1136 DCTTLKEQICDDSR 1149
             C   +E I D +R
Sbjct: 1221 LC---EENIDDCAR 1231



 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 80/322 (24%), Positives = 112/322 (34%), Gaps = 60/322 (18%)

Query: 869  LVAEEMTHNCPNG--CSGKGECL--MG--HCQCQPGFGGDDCSKSVCPVL---CSQRGEY 919
            L+ EE   +C  G  C   G+C+  +G   C+C PGF G+ C   +   L   CS  G  
Sbjct: 1220 LLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSL 1279

Query: 920  ----INGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK-------CSCVRGYKG 966
                +  +  C C   + G+ C    D C    C   G C           C C  G+ G
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSG 1339

Query: 967  ----KFCGEI------DCPHPTCSGHGFC-----IEGTCVCKKGWKGADCGTMDKD---A 1008
                  CG++       C H       FC      E  C       G  C    +    +
Sbjct: 1340 ARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYS 1399

Query: 1009 LQCLPDCSGHG----TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG-RCVGESCSCAA 1063
             QC P  SG      T    T   +C +++  +     VC   C  H  +  G  CS   
Sbjct: 1400 CQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTM 1459

Query: 1064 GWSGEFCSVRL-C----DARCAEHGQCKNGTCLCVS---GWNGRHCTLEGCPRSCAGHGQ 1115
                  CS  L C    + +C E   C    CL  +     N + C  +   + CA H +
Sbjct: 1460 ENPWANCSSPLPCWDYINNQCDE--LCNTVECLFDNFECQGNSKTCKYD---KYCADHFK 1514

Query: 1116 CRVDNDGRWECKCFDGWDGPDC 1137
                + G    +C  GWDG DC
Sbjct: 1515 DNHCDQGCNSEEC--GWDGLDC 1534


>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
            protein.
          Length = 2471

 Score =  134 bits (323), Expect = 6e-30
 Identities = 94/301 (31%), Positives = 131/301 (43%), Gaps = 47/301 (15%)

Query: 880  NGCSGKGEC---LMGH-CQCQPGFGGDDCSKSVCP---------VLCSQRGEYINGECQC 926
            N C  +G C   + G+ C C   + G +C   + P          +C +   + +  C C
Sbjct: 802  NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLC 861

Query: 927  NPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGE--IDCPHPTCS 980
             PGW+G+ C++  DEC    C  HG C N +    C C  G+ G  C E   DC    C 
Sbjct: 862  APGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQ 921

Query: 981  GHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD--VDTQTCSCHAK 1033
              G C++G    +C+C  G+ G  C T   D  +CL + C   GT    V++ TC C A 
Sbjct: 922  NGGSCMDGVNTFSCLCLPGFTGDKCQT---DMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978

Query: 1034 WSGEDCSKEV--CS-LECGPHGRCV----GESCSCAAGWSGEFC--SVRLCDAR-CAEHG 1083
            + G  C   +  C+   C   G CV      SC C  G++G FC   +  C +  C   G
Sbjct: 979  FDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEG 1038

Query: 1084 QCKNG----TCLCVSGWNGRHC-TLEG-CPRS-CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
             C +G     C C  G+ G++C TL   C RS C   G C V      +C C  GW G  
Sbjct: 1039 TCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC-VQKKAESQCLCPSGWAGAY 1097

Query: 1137 C 1137
            C
Sbjct: 1098 C 1098



 Score =  124 bits (298), Expect = 6e-27
 Identities = 95/322 (29%), Positives = 132/322 (40%), Gaps = 45/322 (13%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
            ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 149  LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 208

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGE--IDCPHPT 978
            C  G+ G+ C   +  C    C   G C        +C+C+ G++G  C     DCP+  
Sbjct: 209  CPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR 268

Query: 979  CSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDT--QTCSCH 1031
            C   G C++G     C C   W G  C T D D     P+ C   GT         C C 
Sbjct: 269  CQNGGVCVDGVNTYNCRCPPQWTGQFC-TEDVDECLLQPNACQNGGTCANRNGGYGCVCV 327

Query: 1032 AKWSGEDCSKEV--CSL-ECGPHGRCVGE----SCSCAAGWSGEFCSV-RLCDAR-CAEH 1082
              WSG+DCS+ +  C+   C P   C+      SC C  G +G  C +   C +  C + 
Sbjct: 328  NGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKG 387

Query: 1083 GQCK----NG--TCLCVSGWNGRHCT--LEGCPRS----CAGHGQCRVDNDGRWECKCFD 1130
              C     NG   C C  G+ G  CT  ++ C  +    C   G+C V+ DG + C+C  
Sbjct: 388  ALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKC-VNTDGAFHCECLK 446

Query: 1131 GWDGPDCTTLKEQICDDSRDND 1152
            G+ GP C     +   D   ND
Sbjct: 447  GYAGPRCEMDINECHSDPCQND 468



 Score =  119 bits (287), Expect = 1e-25
 Identities = 94/329 (28%), Positives = 135/329 (41%), Gaps = 48/329 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVL---CSQRGEYING----ECQCNPGWKGKECSLRHDECEVP 945
            C+C PGF G DC + +   L   C   G  ++G     C C PG+ G +C    +EC   
Sbjct: 897  CECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSE 956

Query: 946  DCNGHGHC---VNG-KCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEG----TCVCKKG 995
             C   G C   VN   C C  G+ G  C     +C   +C   G C++G    +C+C  G
Sbjct: 957  PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGP 1050
            + G+ C   + +     P C   GT    + T  CSC   ++G++C   V  CS   C  
Sbjct: 1017 FTGSFC-LHEINECSSHP-CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKN 1074

Query: 1051 HGRCV---GES-CSCAAGWSGEFCSVR--LCDAR-----------CAEHGQCKNG----T 1089
             G CV    ES C C +GW+G +C V    CD             C   G C N      
Sbjct: 1075 KGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY 1134

Query: 1090 CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDD 1147
            C C  G+ G +C   L+ C  +   HG    D  G + C+C  G+ G +C    ++ C +
Sbjct: 1135 CQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDE-CQN 1193

Query: 1148 SRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                +    +D  +   C  P      LC
Sbjct: 1194 QPCQNGGTCIDLVNHFKCSCPPGTRGLLC 1222



 Score =  117 bits (281), Expect = 7e-25
 Identities = 86/296 (29%), Positives = 127/296 (42%), Gaps = 41/296 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNP 928
            N C   G+C+      HC+C  G+ G  C   +  C     Q      + I G  C C P
Sbjct: 425  NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP 484

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EI-DCPHPTCSGH 982
            G+KG  C L  +EC+   C  +G CV+     +C C  G+ G  C  +I DC    C   
Sbjct: 485  GFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNG 544

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSG 1036
              CI+      C C  G+ G  C   +++   C PD   HG     +D+ TC C+  + G
Sbjct: 545  AKCIDHPNGYECQCATGFTGVLC---EENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMG 601

Query: 1037 EDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDARCAEHGQCKN 1087
              CS ++  C S  C   GRC+    G  C+C  G SG  C +    C +    HG C +
Sbjct: 602  AICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMD 661

Query: 1088 G----TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G    +C+C  G+ G+ C   ++ C  +    G   ++    + C C +G   P C
Sbjct: 662  GINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSC 717



 Score =  111 bits (266), Expect = 5e-23
 Identities = 92/339 (27%), Positives = 137/339 (40%), Gaps = 48/339 (14%)

Query: 893  CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
            C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 131  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 190

Query: 947  -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEG-----TCVCKK 994
             C   G C+N     +C C +G+ G++C    + C    C   G C +       C C  
Sbjct: 191  HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 250

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV--CSLE---CG 1049
            G++G+ C     D         G     V+T  C C  +W+G+ C+++V  C L+   C 
Sbjct: 251  GFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310

Query: 1050 PHGRCV----GESCSCAAGWSGEFCSVRLCD---ARCAEHGQC----KNGTCLCVSGWNG 1098
              G C     G  C C  GWSG+ CS  + D   A C     C     + +C+C  G  G
Sbjct: 311  NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370

Query: 1099 RHCTLEGCPRSCAGHGQCRVDN---DGRWECKCFDGWDGPDCTTLKEQICDDSRDN---- 1151
              C L+    S   H     D    +G++ C C  G+ G DCT   ++ C  +  N    
Sbjct: 371  LLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDE-CAMANSNPCEH 429

Query: 1152 -----DKDGLVDCEDPECCQSPACKSS-QLCVSSPKPTD 1184
                 + DG   CE  +    P C+     C S P   D
Sbjct: 430  AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468



 Score =  107 bits (257), Expect = 6e-22
 Identities = 95/340 (27%), Positives = 129/340 (37%), Gaps = 47/340 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVLCSQ--RGEYING----ECQCNPG 929
            N C     C+ G     C C  G     C   V   L +    G    G    +C C+ G
Sbjct: 689  NPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAG 748

Query: 930  WKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCG-EID-CPHPTCSGHG 983
            W G  C +  +EC    C   G C   VNG +C+C +G+KG  C   ID C    C   G
Sbjct: 749  WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQG 808

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF----DVDTQTCSCHAKW 1034
             C +     TC C   + G +C T+      C P+ C          + ++ TC C   W
Sbjct: 809  TCFDDISGYTCHCVLPYTGKNCQTV---LAPCSPNPCENAAVCKESPNFESYTCLCAPGW 865

Query: 1035 SGEDCS---KEVCSLECGPHGRCVGES----CSCAAGWSGEFCSVRLCDA---RCAEHGQ 1084
             G+ C+    E  S  C  HG C        C C  G+SG  C   + D     C   G 
Sbjct: 866  QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGS 925

Query: 1085 CKNG----TCLCVSGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C +G    +CLC+ G+ G  C     E     C   G C  D    + CKC  G+DG  C
Sbjct: 926  CMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCS-DYVNSYTCKCQAGFDGVHC 984

Query: 1138 TTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
                 + C +S   +    VD  +   C  P   +   C+
Sbjct: 985  ENNINE-CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCL 1023



 Score =  105 bits (252), Expect = 2e-21
 Identities = 97/341 (28%), Positives = 135/341 (39%), Gaps = 62/341 (18%)

Query: 882  CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGW 930
            C   G C+      +CQC  G+ G  C + +  C     Q G    ++I G  C+C PG+
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179

Query: 931  KGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDCPH-PTCSGHG 983
            +G  C    DEC+   C   G C+    + KCSC  G +G  C E   DC   P C   G
Sbjct: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGG 1239

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD----VDTQTCSCHAKW 1034
             C++     +C C  G+ G  C   + D  +CL + CS  G+ D     +   C C + +
Sbjct: 1240 QCMDRIGGYSCRCLPGFAGERC---EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296

Query: 1035 SGEDCSK--EVC-SLECGPHGRCV-------GESCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            +G  C    +VC  + C   G C        G  C C  G+SG  C       +C +  Q
Sbjct: 1297 TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQ 1356

Query: 1085 C----KNGTCLCVSGWNGRHCTLEGCPRS-CAGHGQCRVDND-GRWECKC---FDG---- 1131
            C        C C S    R C   GC  S C   G C        + C+C   F G    
Sbjct: 1357 CVHTASGPRCFCPS---PRDCE-SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412

Query: 1132 -WDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACK 1171
             +  P  T     +     D  +DG+ D    E C S AC+
Sbjct: 1413 LYTAPPSTPPATCLSQYCADKARDGVCD----EACNSHACQ 1449



 Score =  101 bits (243), Expect = 3e-20
 Identities = 74/262 (28%), Positives = 104/262 (39%), Gaps = 33/262 (12%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKK 994
            C   G CV      G C C  G+ G++C   D C    C   G C+      + TC C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECG 1049
            G+ G DC             C   GT  +   DT  C+C   ++G++C   + C S  C 
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 1050 PHGRCVGE----SCSCAAGWSGEFC--SVRLCD--ARCAEHGQCKN--GT--CLCVSGWN 1097
                C       SC C  G++G+ C   V  CD    C   G C N  G+  C C  G+ 
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214

Query: 1098 GRHCT---LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKD 1154
            G++C    +   P  C   G CR   D  +EC C  G++G  C    +  C + R  +  
Sbjct: 215  GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDD-CPNHRCQNGG 273

Query: 1155 GLVDCEDPECCQSPACKSSQLC 1176
              VD  +   C+ P   + Q C
Sbjct: 274  VCVDGVNTYNCRCPPQWTGQFC 295



 Score = 98.7 bits (235), Expect = 3e-19
 Identities = 92/353 (26%), Positives = 135/353 (38%), Gaps = 58/353 (16%)

Query: 882  CSGKGECLM-----GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNP 928
            C  +G C+      G+C+C  GF G      D C K+ C     C  +       C+C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 929  GWKGKEC--SLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCS 980
            G+ G++C  S  H       C   G C        +C+C  G+ GK C   D C    C+
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 981  GHGFCI----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHA 1032
                C     + +C C  G+ G  C T   D  +C +P    HG   ++   +  C C  
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCPQ 211

Query: 1033 KWSGEDCSK---EVCSLECGPHGRC--VGE---SCSCAAGWSGEFCSVRLCDA---RCAE 1081
             ++G+ C           C   G C   G+    C+C  G+ G  C   + D    RC  
Sbjct: 212  GFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQN 271

Query: 1082 HGQCKNG----TCLCVSGWNGRHCT--LEGC---PRSCAGHGQCRVDNDGRWECKCFDGW 1132
             G C +G     C C   W G+ CT  ++ C   P +C   G C  + +G + C C +GW
Sbjct: 272  GGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC-ANRNGGYGCVCVNGW 330

Query: 1133 DGPDCTTLKEQIC-----DDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSP 1180
             G DC+   +          S   D+     C  PE      C     C+S+P
Sbjct: 331  SGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383



 Score = 97.1 bits (231), Expect = 9e-19
 Identities = 88/309 (28%), Positives = 125/309 (40%), Gaps = 53/309 (17%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 71   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 129

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 130  ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVD---TQ 1026
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT       T 
Sbjct: 189  P-GHCQHGGTCLNLPGSYQCQCPQGFTGQYC---DSLYVPCAPSPCVNGGTCRQTGDFTF 244

Query: 1027 TCSCHAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLC-- 1075
             C+C   + G  C + +  C +  C   G CV      +C C   W+G+FC+  V  C  
Sbjct: 245  ECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLL 304

Query: 1076 -DARCAEHGQC--KNG--TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKC 1128
                C   G C  +NG   C+CV+GW+G  C+  ++ C  +    G   +D    + C C
Sbjct: 305  QPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMC 364

Query: 1129 FDGWDGPDC 1137
             +G  G  C
Sbjct: 365  PEGKAGLLC 373



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 88/314 (28%), Positives = 125/314 (39%), Gaps = 61/314 (19%)

Query: 878  CPNGCSG-KGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C  G +G K +  M  C  +P   G  CS            +Y+N   C+C  G+ G  C
Sbjct: 937  CLPGFTGDKCQTDMNECLSEPCKNGGTCS------------DYVNSYTCKCQAGFDGVHC 984

Query: 936  SLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI-DCPHPTCSGHGFCIEG- 988
                +EC    C   G CV+G     C C  G+ G FC  EI +C    C   G C++G 
Sbjct: 985  ENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF---DVDTQTCSCHAKWSGEDCSKE 1042
                C C  G+ G +C T+    L     C   GT      ++Q C C + W+G  C   
Sbjct: 1045 GTYRCSCPLGYTGKNCQTLVN--LCSRSPCKNKGTCVQKKAESQ-CLCPSGWAGAYCDVP 1101

Query: 1043 VCSLE-------------CGPHGRCVGES----CSCAAGWSGEFCSVRL--CDARCAEHG 1083
              S +             C   G C+       C C  G++G +C  +L  C +   +HG
Sbjct: 1102 NVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHG 1161

Query: 1084 -QCKN----GTCLCVSGWNGRHCTLE--GCP-RSCAGHGQCRVDNDGRWECKCFDGWDGP 1135
              C +      C CV G+ G +C  E   C  + C   G C +D    ++C C  G  G 
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC-IDLVNHFKCSCPPGTRGL 1220

Query: 1136 DCTTLKEQICDDSR 1149
             C   +E I D +R
Sbjct: 1221 LC---EENIDDCAR 1231



 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 80/322 (24%), Positives = 112/322 (34%), Gaps = 60/322 (18%)

Query: 869  LVAEEMTHNCPNG--CSGKGECL--MG--HCQCQPGFGGDDCSKSVCPVL---CSQRGEY 919
            L+ EE   +C  G  C   G+C+  +G   C+C PGF G+ C   +   L   CS  G  
Sbjct: 1220 LLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSL 1279

Query: 920  ----INGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK-------CSCVRGYKG 966
                +  +  C C   + G+ C    D C    C   G C           C C  G+ G
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSG 1339

Query: 967  ----KFCGEI------DCPHPTCSGHGFC-----IEGTCVCKKGWKGADCGTMDKD---A 1008
                  CG++       C H       FC      E  C       G  C    +    +
Sbjct: 1340 ARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYS 1399

Query: 1009 LQCLPDCSGHG----TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG-RCVGESCSCAA 1063
             QC P  SG      T    T   +C +++  +     VC   C  H  +  G  CS   
Sbjct: 1400 CQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTM 1459

Query: 1064 GWSGEFCSVRL-C----DARCAEHGQCKNGTCLCVS---GWNGRHCTLEGCPRSCAGHGQ 1115
                  CS  L C    + +C E   C    CL  +     N + C  +   + CA H +
Sbjct: 1460 ENPWANCSSPLPCWDYINNQCDE--LCNTVECLFDNFECQGNSKTCKYD---KYCADHFK 1514

Query: 1116 CRVDNDGRWECKCFDGWDGPDC 1137
                + G    +C  GWDG DC
Sbjct: 1515 DNHCDQGCNSEEC--GWDGLDC 1534


>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
            protein.
          Length = 2471

 Score =  134 bits (323), Expect = 6e-30
 Identities = 94/301 (31%), Positives = 131/301 (43%), Gaps = 47/301 (15%)

Query: 880  NGCSGKGEC---LMGH-CQCQPGFGGDDCSKSVCP---------VLCSQRGEYINGECQC 926
            N C  +G C   + G+ C C   + G +C   + P          +C +   + +  C C
Sbjct: 802  NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLC 861

Query: 927  NPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGE--IDCPHPTCS 980
             PGW+G+ C++  DEC    C  HG C N +    C C  G+ G  C E   DC    C 
Sbjct: 862  APGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQ 921

Query: 981  GHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD--VDTQTCSCHAK 1033
              G C++G    +C+C  G+ G  C T   D  +CL + C   GT    V++ TC C A 
Sbjct: 922  NGGSCMDGVNTFSCLCLPGFTGDKCQT---DMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978

Query: 1034 WSGEDCSKEV--CS-LECGPHGRCV----GESCSCAAGWSGEFC--SVRLCDAR-CAEHG 1083
            + G  C   +  C+   C   G CV      SC C  G++G FC   +  C +  C   G
Sbjct: 979  FDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEG 1038

Query: 1084 QCKNG----TCLCVSGWNGRHC-TLEG-CPRS-CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
             C +G     C C  G+ G++C TL   C RS C   G C V      +C C  GW G  
Sbjct: 1039 TCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC-VQKKAESQCLCPSGWAGAY 1097

Query: 1137 C 1137
            C
Sbjct: 1098 C 1098



 Score =  124 bits (298), Expect = 6e-27
 Identities = 95/322 (29%), Positives = 132/322 (40%), Gaps = 45/322 (13%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
            ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 149  LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 208

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGE--IDCPHPT 978
            C  G+ G+ C   +  C    C   G C        +C+C+ G++G  C     DCP+  
Sbjct: 209  CPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR 268

Query: 979  CSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDT--QTCSCH 1031
            C   G C++G     C C   W G  C T D D     P+ C   GT         C C 
Sbjct: 269  CQNGGVCVDGVNTYNCRCPPQWTGQFC-TEDVDECLLQPNACQNGGTCANRNGGYGCVCV 327

Query: 1032 AKWSGEDCSKEV--CSL-ECGPHGRCVGE----SCSCAAGWSGEFCSV-RLCDAR-CAEH 1082
              WSG+DCS+ +  C+   C P   C+      SC C  G +G  C +   C +  C + 
Sbjct: 328  NGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKG 387

Query: 1083 GQCK----NG--TCLCVSGWNGRHCT--LEGCPRS----CAGHGQCRVDNDGRWECKCFD 1130
              C     NG   C C  G+ G  CT  ++ C  +    C   G+C V+ DG + C+C  
Sbjct: 388  ALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKC-VNTDGAFHCECLK 446

Query: 1131 GWDGPDCTTLKEQICDDSRDND 1152
            G+ GP C     +   D   ND
Sbjct: 447  GYAGPRCEMDINECHSDPCQND 468



 Score =  119 bits (287), Expect = 1e-25
 Identities = 94/329 (28%), Positives = 135/329 (41%), Gaps = 48/329 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVL---CSQRGEYING----ECQCNPGWKGKECSLRHDECEVP 945
            C+C PGF G DC + +   L   C   G  ++G     C C PG+ G +C    +EC   
Sbjct: 897  CECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSE 956

Query: 946  DCNGHGHC---VNG-KCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEG----TCVCKKG 995
             C   G C   VN   C C  G+ G  C     +C   +C   G C++G    +C+C  G
Sbjct: 957  PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGP 1050
            + G+ C   + +     P C   GT    + T  CSC   ++G++C   V  CS   C  
Sbjct: 1017 FTGSFC-LHEINECSSHP-CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKN 1074

Query: 1051 HGRCV---GES-CSCAAGWSGEFCSVR--LCDAR-----------CAEHGQCKNG----T 1089
             G CV    ES C C +GW+G +C V    CD             C   G C N      
Sbjct: 1075 KGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY 1134

Query: 1090 CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDD 1147
            C C  G+ G +C   L+ C  +   HG    D  G + C+C  G+ G +C    ++ C +
Sbjct: 1135 CQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDE-CQN 1193

Query: 1148 SRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                +    +D  +   C  P      LC
Sbjct: 1194 QPCQNGGTCIDLVNHFKCSCPPGTRGLLC 1222



 Score =  117 bits (281), Expect = 7e-25
 Identities = 86/296 (29%), Positives = 127/296 (42%), Gaps = 41/296 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNP 928
            N C   G+C+      HC+C  G+ G  C   +  C     Q      + I G  C C P
Sbjct: 425  NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP 484

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EI-DCPHPTCSGH 982
            G+KG  C L  +EC+   C  +G CV+     +C C  G+ G  C  +I DC    C   
Sbjct: 485  GFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNG 544

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSG 1036
              CI+      C C  G+ G  C   +++   C PD   HG     +D+ TC C+  + G
Sbjct: 545  AKCIDHPNGYECQCATGFTGVLC---EENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMG 601

Query: 1037 EDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDARCAEHGQCKN 1087
              CS ++  C S  C   GRC+    G  C+C  G SG  C +    C +    HG C +
Sbjct: 602  AICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMD 661

Query: 1088 G----TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G    +C+C  G+ G+ C   ++ C  +    G   ++    + C C +G   P C
Sbjct: 662  GINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSC 717



 Score =  111 bits (266), Expect = 5e-23
 Identities = 92/339 (27%), Positives = 137/339 (40%), Gaps = 48/339 (14%)

Query: 893  CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
            C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 131  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 190

Query: 947  -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEG-----TCVCKK 994
             C   G C+N     +C C +G+ G++C    + C    C   G C +       C C  
Sbjct: 191  HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 250

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV--CSLE---CG 1049
            G++G+ C     D         G     V+T  C C  +W+G+ C+++V  C L+   C 
Sbjct: 251  GFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310

Query: 1050 PHGRCV----GESCSCAAGWSGEFCSVRLCD---ARCAEHGQC----KNGTCLCVSGWNG 1098
              G C     G  C C  GWSG+ CS  + D   A C     C     + +C+C  G  G
Sbjct: 311  NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370

Query: 1099 RHCTLEGCPRSCAGHGQCRVDN---DGRWECKCFDGWDGPDCTTLKEQICDDSRDN---- 1151
              C L+    S   H     D    +G++ C C  G+ G DCT   ++ C  +  N    
Sbjct: 371  LLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDE-CAMANSNPCEH 429

Query: 1152 -----DKDGLVDCEDPECCQSPACKSS-QLCVSSPKPTD 1184
                 + DG   CE  +    P C+     C S P   D
Sbjct: 430  AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468



 Score =  107 bits (257), Expect = 6e-22
 Identities = 95/340 (27%), Positives = 129/340 (37%), Gaps = 47/340 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVLCSQ--RGEYING----ECQCNPG 929
            N C     C+ G     C C  G     C   V   L +    G    G    +C C+ G
Sbjct: 689  NPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAG 748

Query: 930  WKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCG-EID-CPHPTCSGHG 983
            W G  C +  +EC    C   G C   VNG +C+C +G+KG  C   ID C    C   G
Sbjct: 749  WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQG 808

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF----DVDTQTCSCHAKW 1034
             C +     TC C   + G +C T+      C P+ C          + ++ TC C   W
Sbjct: 809  TCFDDISGYTCHCVLPYTGKNCQTV---LAPCSPNPCENAAVCKESPNFESYTCLCAPGW 865

Query: 1035 SGEDCS---KEVCSLECGPHGRCVGES----CSCAAGWSGEFCSVRLCDA---RCAEHGQ 1084
             G+ C+    E  S  C  HG C        C C  G+SG  C   + D     C   G 
Sbjct: 866  QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGS 925

Query: 1085 CKNG----TCLCVSGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C +G    +CLC+ G+ G  C     E     C   G C  D    + CKC  G+DG  C
Sbjct: 926  CMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCS-DYVNSYTCKCQAGFDGVHC 984

Query: 1138 TTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
                 + C +S   +    VD  +   C  P   +   C+
Sbjct: 985  ENNINE-CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCL 1023



 Score =  105 bits (252), Expect = 2e-21
 Identities = 97/341 (28%), Positives = 135/341 (39%), Gaps = 62/341 (18%)

Query: 882  CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGW 930
            C   G C+      +CQC  G+ G  C + +  C     Q G    ++I G  C+C PG+
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179

Query: 931  KGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDCPH-PTCSGHG 983
            +G  C    DEC+   C   G C+    + KCSC  G +G  C E   DC   P C   G
Sbjct: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGG 1239

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD----VDTQTCSCHAKW 1034
             C++     +C C  G+ G  C   + D  +CL + CS  G+ D     +   C C + +
Sbjct: 1240 QCMDRIGGYSCRCLPGFAGERC---EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296

Query: 1035 SGEDCSK--EVC-SLECGPHGRCV-------GESCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            +G  C    +VC  + C   G C        G  C C  G+SG  C       +C +  Q
Sbjct: 1297 TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQ 1356

Query: 1085 C----KNGTCLCVSGWNGRHCTLEGCPRS-CAGHGQCRVDND-GRWECKC---FDG---- 1131
            C        C C S    R C   GC  S C   G C        + C+C   F G    
Sbjct: 1357 CVHTASGPRCFCPS---PRDCE-SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412

Query: 1132 -WDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACK 1171
             +  P  T     +     D  +DG+ D    E C S AC+
Sbjct: 1413 LYTAPPSTPPATCLSQYCADKARDGVCD----EACNSHACQ 1449



 Score =  101 bits (243), Expect = 3e-20
 Identities = 74/262 (28%), Positives = 104/262 (39%), Gaps = 33/262 (12%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKK 994
            C   G CV      G C C  G+ G++C   D C    C   G C+      + TC C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECG 1049
            G+ G DC             C   GT  +   DT  C+C   ++G++C   + C S  C 
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 1050 PHGRCVGE----SCSCAAGWSGEFC--SVRLCD--ARCAEHGQCKN--GT--CLCVSGWN 1097
                C       SC C  G++G+ C   V  CD    C   G C N  G+  C C  G+ 
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214

Query: 1098 GRHCT---LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKD 1154
            G++C    +   P  C   G CR   D  +EC C  G++G  C    +  C + R  +  
Sbjct: 215  GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDD-CPNHRCQNGG 273

Query: 1155 GLVDCEDPECCQSPACKSSQLC 1176
              VD  +   C+ P   + Q C
Sbjct: 274  VCVDGVNTYNCRCPPQWTGQFC 295



 Score = 98.7 bits (235), Expect = 3e-19
 Identities = 92/353 (26%), Positives = 135/353 (38%), Gaps = 58/353 (16%)

Query: 882  CSGKGECLM-----GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNP 928
            C  +G C+      G+C+C  GF G      D C K+ C     C  +       C+C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 929  GWKGKEC--SLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCS 980
            G+ G++C  S  H       C   G C        +C+C  G+ GK C   D C    C+
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 981  GHGFCI----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHA 1032
                C     + +C C  G+ G  C T   D  +C +P    HG   ++   +  C C  
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCPQ 211

Query: 1033 KWSGEDCSK---EVCSLECGPHGRC--VGE---SCSCAAGWSGEFCSVRLCDA---RCAE 1081
             ++G+ C           C   G C   G+    C+C  G+ G  C   + D    RC  
Sbjct: 212  GFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQN 271

Query: 1082 HGQCKNG----TCLCVSGWNGRHCT--LEGC---PRSCAGHGQCRVDNDGRWECKCFDGW 1132
             G C +G     C C   W G+ CT  ++ C   P +C   G C  + +G + C C +GW
Sbjct: 272  GGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC-ANRNGGYGCVCVNGW 330

Query: 1133 DGPDCTTLKEQIC-----DDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSP 1180
             G DC+   +          S   D+     C  PE      C     C+S+P
Sbjct: 331  SGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383



 Score = 97.1 bits (231), Expect = 9e-19
 Identities = 88/309 (28%), Positives = 125/309 (40%), Gaps = 53/309 (17%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 71   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 129

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 130  ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVD---TQ 1026
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT       T 
Sbjct: 189  P-GHCQHGGTCLNLPGSYQCQCPQGFTGQYC---DSLYVPCAPSPCVNGGTCRQTGDFTF 244

Query: 1027 TCSCHAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLC-- 1075
             C+C   + G  C + +  C +  C   G CV      +C C   W+G+FC+  V  C  
Sbjct: 245  ECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLL 304

Query: 1076 -DARCAEHGQC--KNG--TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKC 1128
                C   G C  +NG   C+CV+GW+G  C+  ++ C  +    G   +D    + C C
Sbjct: 305  QPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMC 364

Query: 1129 FDGWDGPDC 1137
             +G  G  C
Sbjct: 365  PEGKAGLLC 373



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 88/314 (28%), Positives = 125/314 (39%), Gaps = 61/314 (19%)

Query: 878  CPNGCSG-KGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C  G +G K +  M  C  +P   G  CS            +Y+N   C+C  G+ G  C
Sbjct: 937  CLPGFTGDKCQTDMNECLSEPCKNGGTCS------------DYVNSYTCKCQAGFDGVHC 984

Query: 936  SLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI-DCPHPTCSGHGFCIEG- 988
                +EC    C   G CV+G     C C  G+ G FC  EI +C    C   G C++G 
Sbjct: 985  ENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF---DVDTQTCSCHAKWSGEDCSKE 1042
                C C  G+ G +C T+    L     C   GT      ++Q C C + W+G  C   
Sbjct: 1045 GTYRCSCPLGYTGKNCQTLVN--LCSRSPCKNKGTCVQKKAESQ-CLCPSGWAGAYCDVP 1101

Query: 1043 VCSLE-------------CGPHGRCVGES----CSCAAGWSGEFCSVRL--CDARCAEHG 1083
              S +             C   G C+       C C  G++G +C  +L  C +   +HG
Sbjct: 1102 NVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHG 1161

Query: 1084 -QCKN----GTCLCVSGWNGRHCTLE--GCP-RSCAGHGQCRVDNDGRWECKCFDGWDGP 1135
              C +      C CV G+ G +C  E   C  + C   G C +D    ++C C  G  G 
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC-IDLVNHFKCSCPPGTRGL 1220

Query: 1136 DCTTLKEQICDDSR 1149
             C   +E I D +R
Sbjct: 1221 LC---EENIDDCAR 1231



 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 80/322 (24%), Positives = 112/322 (34%), Gaps = 60/322 (18%)

Query: 869  LVAEEMTHNCPNG--CSGKGECL--MG--HCQCQPGFGGDDCSKSVCPVL---CSQRGEY 919
            L+ EE   +C  G  C   G+C+  +G   C+C PGF G+ C   +   L   CS  G  
Sbjct: 1220 LLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSL 1279

Query: 920  ----INGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK-------CSCVRGYKG 966
                +  +  C C   + G+ C    D C    C   G C           C C  G+ G
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSG 1339

Query: 967  ----KFCGEI------DCPHPTCSGHGFC-----IEGTCVCKKGWKGADCGTMDKD---A 1008
                  CG++       C H       FC      E  C       G  C    +    +
Sbjct: 1340 ARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYS 1399

Query: 1009 LQCLPDCSGHG----TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG-RCVGESCSCAA 1063
             QC P  SG      T    T   +C +++  +     VC   C  H  +  G  CS   
Sbjct: 1400 CQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTM 1459

Query: 1064 GWSGEFCSVRL-C----DARCAEHGQCKNGTCLCVS---GWNGRHCTLEGCPRSCAGHGQ 1115
                  CS  L C    + +C E   C    CL  +     N + C  +   + CA H +
Sbjct: 1460 ENPWANCSSPLPCWDYINNQCDE--LCNTVECLFDNFECQGNSKTCKYD---KYCADHFK 1514

Query: 1116 CRVDNDGRWECKCFDGWDGPDC 1137
                + G    +C  GWDG DC
Sbjct: 1515 DNHCDQGCNSEEC--GWDGLDC 1534


>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
          Length = 2471

 Score =  134 bits (323), Expect = 6e-30
 Identities = 94/301 (31%), Positives = 131/301 (43%), Gaps = 47/301 (15%)

Query: 880  NGCSGKGEC---LMGH-CQCQPGFGGDDCSKSVCP---------VLCSQRGEYINGECQC 926
            N C  +G C   + G+ C C   + G +C   + P          +C +   + +  C C
Sbjct: 802  NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLC 861

Query: 927  NPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGE--IDCPHPTCS 980
             PGW+G+ C++  DEC    C  HG C N +    C C  G+ G  C E   DC    C 
Sbjct: 862  APGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQ 921

Query: 981  GHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD--VDTQTCSCHAK 1033
              G C++G    +C+C  G+ G  C T   D  +CL + C   GT    V++ TC C A 
Sbjct: 922  NGGSCMDGVNTFSCLCLPGFTGDKCQT---DMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978

Query: 1034 WSGEDCSKEV--CS-LECGPHGRCV----GESCSCAAGWSGEFC--SVRLCDAR-CAEHG 1083
            + G  C   +  C+   C   G CV      SC C  G++G FC   +  C +  C   G
Sbjct: 979  FDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEG 1038

Query: 1084 QCKNG----TCLCVSGWNGRHC-TLEG-CPRS-CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
             C +G     C C  G+ G++C TL   C RS C   G C V      +C C  GW G  
Sbjct: 1039 TCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC-VQKKAESQCLCPSGWAGAY 1097

Query: 1137 C 1137
            C
Sbjct: 1098 C 1098



 Score =  123 bits (297), Expect = 9e-27
 Identities = 95/322 (29%), Positives = 132/322 (40%), Gaps = 45/322 (13%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
            ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 149  LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 208

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGE--IDCPHPT 978
            C  G+ G+ C   +  C    C   G C        +C+C+ G++G  C     DCP+  
Sbjct: 209  CLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR 268

Query: 979  CSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDT--QTCSCH 1031
            C   G C++G     C C   W G  C T D D     P+ C   GT         C C 
Sbjct: 269  CQNGGVCVDGVNTYNCRCPPQWTGQFC-TEDVDECLLQPNACQNGGTCANRNGGYGCVCV 327

Query: 1032 AKWSGEDCSKEV--CSL-ECGPHGRCVGE----SCSCAAGWSGEFCSV-RLCDAR-CAEH 1082
              WSG+DCS+ +  C+   C P   C+      SC C  G +G  C +   C +  C + 
Sbjct: 328  NGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKG 387

Query: 1083 GQCK----NG--TCLCVSGWNGRHCT--LEGCPRS----CAGHGQCRVDNDGRWECKCFD 1130
              C     NG   C C  G+ G  CT  ++ C  +    C   G+C V+ DG + C+C  
Sbjct: 388  ALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKC-VNTDGAFHCECLK 446

Query: 1131 GWDGPDCTTLKEQICDDSRDND 1152
            G+ GP C     +   D   ND
Sbjct: 447  GYAGPRCEMDINECHSDPCQND 468



 Score =  119 bits (287), Expect = 1e-25
 Identities = 94/329 (28%), Positives = 135/329 (41%), Gaps = 48/329 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVL---CSQRGEYING----ECQCNPGWKGKECSLRHDECEVP 945
            C+C PGF G DC + +   L   C   G  ++G     C C PG+ G +C    +EC   
Sbjct: 897  CECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSE 956

Query: 946  DCNGHGHC---VNG-KCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEG----TCVCKKG 995
             C   G C   VN   C C  G+ G  C     +C   +C   G C++G    +C+C  G
Sbjct: 957  PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGP 1050
            + G+ C   + +     P C   GT    + T  CSC   ++G++C   V  CS   C  
Sbjct: 1017 FTGSFC-LHEINECSSHP-CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKN 1074

Query: 1051 HGRCV---GES-CSCAAGWSGEFCSVR--LCDAR-----------CAEHGQCKNG----T 1089
             G CV    ES C C +GW+G +C V    CD             C   G C N      
Sbjct: 1075 KGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY 1134

Query: 1090 CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDD 1147
            C C  G+ G +C   L+ C  +   HG    D  G + C+C  G+ G +C    ++ C +
Sbjct: 1135 CQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDE-CQN 1193

Query: 1148 SRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                +    +D  +   C  P      LC
Sbjct: 1194 QPCQNGGTCIDLVNHFKCSCPPGTRGLLC 1222



 Score =  117 bits (281), Expect = 7e-25
 Identities = 86/296 (29%), Positives = 127/296 (42%), Gaps = 41/296 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNP 928
            N C   G+C+      HC+C  G+ G  C   +  C     Q      + I G  C C P
Sbjct: 425  NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP 484

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EI-DCPHPTCSGH 982
            G+KG  C L  +EC+   C  +G CV+     +C C  G+ G  C  +I DC    C   
Sbjct: 485  GFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNG 544

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSG 1036
              CI+      C C  G+ G  C   +++   C PD   HG     +D+ TC C+  + G
Sbjct: 545  AKCIDHPNGYECQCATGFTGVLC---EENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMG 601

Query: 1037 EDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDARCAEHGQCKN 1087
              CS ++  C S  C   GRC+    G  C+C  G SG  C +    C +    HG C +
Sbjct: 602  AICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMD 661

Query: 1088 G----TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G    +C+C  G+ G+ C   ++ C  +    G   ++    + C C +G   P C
Sbjct: 662  GINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSC 717



 Score =  112 bits (269), Expect = 2e-23
 Identities = 92/339 (27%), Positives = 138/339 (40%), Gaps = 48/339 (14%)

Query: 893  CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
            C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 131  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 190

Query: 947  -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEG-----TCVCKK 994
             C   G C+N     +C C++G+ G++C    + C    C   G C +       C C  
Sbjct: 191  HCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 250

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV--CSLE---CG 1049
            G++G+ C     D         G     V+T  C C  +W+G+ C+++V  C L+   C 
Sbjct: 251  GFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310

Query: 1050 PHGRCV----GESCSCAAGWSGEFCSVRLCD---ARCAEHGQC----KNGTCLCVSGWNG 1098
              G C     G  C C  GWSG+ CS  + D   A C     C     + +C+C  G  G
Sbjct: 311  NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370

Query: 1099 RHCTLEGCPRSCAGHGQCRVDN---DGRWECKCFDGWDGPDCTTLKEQICDDSRDN---- 1151
              C L+    S   H     D    +G++ C C  G+ G DCT   ++ C  +  N    
Sbjct: 371  LLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDE-CAMANSNPCEH 429

Query: 1152 -----DKDGLVDCEDPECCQSPACKSS-QLCVSSPKPTD 1184
                 + DG   CE  +    P C+     C S P   D
Sbjct: 430  AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468



 Score =  107 bits (257), Expect = 6e-22
 Identities = 95/340 (27%), Positives = 129/340 (37%), Gaps = 47/340 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVLCSQ--RGEYING----ECQCNPG 929
            N C     C+ G     C C  G     C   V   L +    G    G    +C C+ G
Sbjct: 689  NPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAG 748

Query: 930  WKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCG-EID-CPHPTCSGHG 983
            W G  C +  +EC    C   G C   VNG +C+C +G+KG  C   ID C    C   G
Sbjct: 749  WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQG 808

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF----DVDTQTCSCHAKW 1034
             C +     TC C   + G +C T+      C P+ C          + ++ TC C   W
Sbjct: 809  TCFDDISGYTCHCVLPYTGKNCQTV---LAPCSPNPCENAAVCKESPNFESYTCLCAPGW 865

Query: 1035 SGEDCS---KEVCSLECGPHGRCVGES----CSCAAGWSGEFCSVRLCDA---RCAEHGQ 1084
             G+ C+    E  S  C  HG C        C C  G+SG  C   + D     C   G 
Sbjct: 866  QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGS 925

Query: 1085 CKNG----TCLCVSGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C +G    +CLC+ G+ G  C     E     C   G C  D    + CKC  G+DG  C
Sbjct: 926  CMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCS-DYVNSYTCKCQAGFDGVHC 984

Query: 1138 TTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
                 + C +S   +    VD  +   C  P   +   C+
Sbjct: 985  ENNINE-CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCL 1023



 Score =  105 bits (252), Expect = 2e-21
 Identities = 97/341 (28%), Positives = 135/341 (39%), Gaps = 62/341 (18%)

Query: 882  CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGW 930
            C   G C+      +CQC  G+ G  C + +  C     Q G    ++I G  C+C PG+
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179

Query: 931  KGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDCPH-PTCSGHG 983
            +G  C    DEC+   C   G C+    + KCSC  G +G  C E   DC   P C   G
Sbjct: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGG 1239

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD----VDTQTCSCHAKW 1034
             C++     +C C  G+ G  C   + D  +CL + CS  G+ D     +   C C + +
Sbjct: 1240 QCMDRIGGYSCRCLPGFAGERC---EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296

Query: 1035 SGEDCSK--EVC-SLECGPHGRCV-------GESCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            +G  C    +VC  + C   G C        G  C C  G+SG  C       +C +  Q
Sbjct: 1297 TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQ 1356

Query: 1085 C----KNGTCLCVSGWNGRHCTLEGCPRS-CAGHGQCRVDND-GRWECKC---FDG---- 1131
            C        C C S    R C   GC  S C   G C        + C+C   F G    
Sbjct: 1357 CVHTASGPRCFCPS---PRDCE-SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412

Query: 1132 -WDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACK 1171
             +  P  T     +     D  +DG+ D    E C S AC+
Sbjct: 1413 LYTAPPSTPPATCLSQYCADKARDGVCD----EACNSHACQ 1449



 Score =  103 bits (246), Expect = 1e-20
 Identities = 74/262 (28%), Positives = 105/262 (40%), Gaps = 33/262 (12%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKK 994
            C   G CV      G C C  G+ G++C   D C    C   G C+      + TC C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECG 1049
            G+ G DC             C   GT  +   DT  C+C   ++G++C   + C S  C 
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 1050 PHGRCVGE----SCSCAAGWSGEFC--SVRLCD--ARCAEHGQCKN--GT--CLCVSGWN 1097
                C       SC C  G++G+ C   V  CD    C   G C N  G+  C C+ G+ 
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFT 214

Query: 1098 GRHCT---LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKD 1154
            G++C    +   P  C   G CR   D  +EC C  G++G  C    +  C + R  +  
Sbjct: 215  GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDD-CPNHRCQNGG 273

Query: 1155 GLVDCEDPECCQSPACKSSQLC 1176
              VD  +   C+ P   + Q C
Sbjct: 274  VCVDGVNTYNCRCPPQWTGQFC 295



 Score = 98.3 bits (234), Expect = 4e-19
 Identities = 92/353 (26%), Positives = 135/353 (38%), Gaps = 58/353 (16%)

Query: 882  CSGKGECLM-----GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNP 928
            C  +G C+      G+C+C  GF G      D C K+ C     C  +       C+C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 929  GWKGKEC--SLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCS 980
            G+ G++C  S  H       C   G C        +C+C  G+ GK C   D C    C+
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 981  GHGFCI----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHA 1032
                C     + +C C  G+ G  C T   D  +C +P    HG   ++   +  C C  
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCLQ 211

Query: 1033 KWSGEDCSK---EVCSLECGPHGRC--VGE---SCSCAAGWSGEFCSVRLCDA---RCAE 1081
             ++G+ C           C   G C   G+    C+C  G+ G  C   + D    RC  
Sbjct: 212  GFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQN 271

Query: 1082 HGQCKNG----TCLCVSGWNGRHCT--LEGC---PRSCAGHGQCRVDNDGRWECKCFDGW 1132
             G C +G     C C   W G+ CT  ++ C   P +C   G C  + +G + C C +GW
Sbjct: 272  GGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC-ANRNGGYGCVCVNGW 330

Query: 1133 DGPDCTTLKEQIC-----DDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSP 1180
             G DC+   +          S   D+     C  PE      C     C+S+P
Sbjct: 331  SGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383



 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 88/309 (28%), Positives = 125/309 (40%), Gaps = 53/309 (17%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 71   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 129

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 130  ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVD---TQ 1026
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT       T 
Sbjct: 189  P-GHCQHGGTCLNLPGSYQCQCLQGFTGQYC---DSLYVPCAPSPCVNGGTCRQTGDFTF 244

Query: 1027 TCSCHAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLC-- 1075
             C+C   + G  C + +  C +  C   G CV      +C C   W+G+FC+  V  C  
Sbjct: 245  ECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLL 304

Query: 1076 -DARCAEHGQC--KNG--TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKC 1128
                C   G C  +NG   C+CV+GW+G  C+  ++ C  +    G   +D    + C C
Sbjct: 305  QPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMC 364

Query: 1129 FDGWDGPDC 1137
             +G  G  C
Sbjct: 365  PEGKAGLLC 373



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 88/314 (28%), Positives = 125/314 (39%), Gaps = 61/314 (19%)

Query: 878  CPNGCSG-KGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C  G +G K +  M  C  +P   G  CS            +Y+N   C+C  G+ G  C
Sbjct: 937  CLPGFTGDKCQTDMNECLSEPCKNGGTCS------------DYVNSYTCKCQAGFDGVHC 984

Query: 936  SLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI-DCPHPTCSGHGFCIEG- 988
                +EC    C   G CV+G     C C  G+ G FC  EI +C    C   G C++G 
Sbjct: 985  ENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF---DVDTQTCSCHAKWSGEDCSKE 1042
                C C  G+ G +C T+    L     C   GT      ++Q C C + W+G  C   
Sbjct: 1045 GTYRCSCPLGYTGKNCQTLVN--LCSRSPCKNKGTCVQKKAESQ-CLCPSGWAGAYCDVP 1101

Query: 1043 VCSLE-------------CGPHGRCVGES----CSCAAGWSGEFCSVRL--CDARCAEHG 1083
              S +             C   G C+       C C  G++G +C  +L  C +   +HG
Sbjct: 1102 NVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHG 1161

Query: 1084 -QCKN----GTCLCVSGWNGRHCTLE--GCP-RSCAGHGQCRVDNDGRWECKCFDGWDGP 1135
              C +      C CV G+ G +C  E   C  + C   G C +D    ++C C  G  G 
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC-IDLVNHFKCSCPPGTRGL 1220

Query: 1136 DCTTLKEQICDDSR 1149
             C   +E I D +R
Sbjct: 1221 LC---EENIDDCAR 1231



 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 80/322 (24%), Positives = 112/322 (34%), Gaps = 60/322 (18%)

Query: 869  LVAEEMTHNCPNG--CSGKGECL--MG--HCQCQPGFGGDDCSKSVCPVL---CSQRGEY 919
            L+ EE   +C  G  C   G+C+  +G   C+C PGF G+ C   +   L   CS  G  
Sbjct: 1220 LLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSL 1279

Query: 920  ----INGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK-------CSCVRGYKG 966
                +  +  C C   + G+ C    D C    C   G C           C C  G+ G
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSG 1339

Query: 967  ----KFCGEI------DCPHPTCSGHGFC-----IEGTCVCKKGWKGADCGTMDKD---A 1008
                  CG++       C H       FC      E  C       G  C    +    +
Sbjct: 1340 ARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYS 1399

Query: 1009 LQCLPDCSGHG----TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG-RCVGESCSCAA 1063
             QC P  SG      T    T   +C +++  +     VC   C  H  +  G  CS   
Sbjct: 1400 CQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTM 1459

Query: 1064 GWSGEFCSVRL-C----DARCAEHGQCKNGTCLCVS---GWNGRHCTLEGCPRSCAGHGQ 1115
                  CS  L C    + +C E   C    CL  +     N + C  +   + CA H +
Sbjct: 1460 ENPWANCSSPLPCWDYINNQCDE--LCNTVECLFDNFECQGNSKTCKYD---KYCADHFK 1514

Query: 1116 CRVDNDGRWECKCFDGWDGPDC 1137
                + G    +C  GWDG DC
Sbjct: 1515 DNHCDQGCNSEEC--GWDGLDC 1534


>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
          Length = 2471

 Score =  134 bits (323), Expect = 6e-30
 Identities = 94/301 (31%), Positives = 131/301 (43%), Gaps = 47/301 (15%)

Query: 880  NGCSGKGEC---LMGH-CQCQPGFGGDDCSKSVCP---------VLCSQRGEYINGECQC 926
            N C  +G C   + G+ C C   + G +C   + P          +C +   + +  C C
Sbjct: 802  NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLC 861

Query: 927  NPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGE--IDCPHPTCS 980
             PGW+G+ C++  DEC    C  HG C N +    C C  G+ G  C E   DC    C 
Sbjct: 862  APGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQ 921

Query: 981  GHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD--VDTQTCSCHAK 1033
              G C++G    +C+C  G+ G  C T   D  +CL + C   GT    V++ TC C A 
Sbjct: 922  NGGSCMDGVNTFSCLCLPGFTGDKCQT---DMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978

Query: 1034 WSGEDCSKEV--CS-LECGPHGRCV----GESCSCAAGWSGEFC--SVRLCDAR-CAEHG 1083
            + G  C   +  C+   C   G CV      SC C  G++G FC   +  C +  C   G
Sbjct: 979  FDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEG 1038

Query: 1084 QCKNG----TCLCVSGWNGRHC-TLEG-CPRS-CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
             C +G     C C  G+ G++C TL   C RS C   G C V      +C C  GW G  
Sbjct: 1039 TCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC-VQKKAESQCLCPSGWAGAY 1097

Query: 1137 C 1137
            C
Sbjct: 1098 C 1098



 Score =  124 bits (298), Expect = 6e-27
 Identities = 95/322 (29%), Positives = 132/322 (40%), Gaps = 45/322 (13%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
            ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 149  LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 208

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGE--IDCPHPT 978
            C  G+ G+ C   +  C    C   G C        +C+C+ G++G  C     DCP+  
Sbjct: 209  CPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR 268

Query: 979  CSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDT--QTCSCH 1031
            C   G C++G     C C   W G  C T D D     P+ C   GT         C C 
Sbjct: 269  CQNGGVCVDGVNTYNCRCPPQWTGQFC-TEDVDECLLQPNACQNGGTCANRNGGYGCVCV 327

Query: 1032 AKWSGEDCSKEV--CSL-ECGPHGRCVGE----SCSCAAGWSGEFCSV-RLCDAR-CAEH 1082
              WSG+DCS+ +  C+   C P   C+      SC C  G +G  C +   C +  C + 
Sbjct: 328  NGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKG 387

Query: 1083 GQCK----NG--TCLCVSGWNGRHCT--LEGCPRS----CAGHGQCRVDNDGRWECKCFD 1130
              C     NG   C C  G+ G  CT  ++ C  +    C   G+C V+ DG + C+C  
Sbjct: 388  ALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKC-VNTDGAFHCECLK 446

Query: 1131 GWDGPDCTTLKEQICDDSRDND 1152
            G+ GP C     +   D   ND
Sbjct: 447  GYAGPRCEMDINECHSDPCQND 468



 Score =  119 bits (287), Expect = 1e-25
 Identities = 94/329 (28%), Positives = 135/329 (41%), Gaps = 48/329 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVL---CSQRGEYING----ECQCNPGWKGKECSLRHDECEVP 945
            C+C PGF G DC + +   L   C   G  ++G     C C PG+ G +C    +EC   
Sbjct: 897  CECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSE 956

Query: 946  DCNGHGHC---VNG-KCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEG----TCVCKKG 995
             C   G C   VN   C C  G+ G  C     +C   +C   G C++G    +C+C  G
Sbjct: 957  PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGP 1050
            + G+ C   + +     P C   GT    + T  CSC   ++G++C   V  CS   C  
Sbjct: 1017 FTGSFC-LHEINECSSHP-CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKN 1074

Query: 1051 HGRCV---GES-CSCAAGWSGEFCSVR--LCDAR-----------CAEHGQCKNG----T 1089
             G CV    ES C C +GW+G +C V    CD             C   G C N      
Sbjct: 1075 KGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY 1134

Query: 1090 CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDD 1147
            C C  G+ G +C   L+ C  +   HG    D  G + C+C  G+ G +C    ++ C +
Sbjct: 1135 CQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDE-CQN 1193

Query: 1148 SRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
                +    +D  +   C  P      LC
Sbjct: 1194 QPCQNGGTCIDLVNHFKCSCPPGTRGLLC 1222



 Score =  117 bits (281), Expect = 7e-25
 Identities = 86/296 (29%), Positives = 127/296 (42%), Gaps = 41/296 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNP 928
            N C   G+C+      HC+C  G+ G  C   +  C     Q      + I G  C C P
Sbjct: 425  NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP 484

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EI-DCPHPTCSGH 982
            G+KG  C L  +EC+   C  +G CV+     +C C  G+ G  C  +I DC    C   
Sbjct: 485  GFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNG 544

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSG 1036
              CI+      C C  G+ G  C   +++   C PD   HG     +D+ TC C+  + G
Sbjct: 545  AKCIDHPNGYECQCATGFTGVLC---EENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMG 601

Query: 1037 EDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDARCAEHGQCKN 1087
              CS ++  C S  C   GRC+    G  C+C  G SG  C +    C +    HG C +
Sbjct: 602  AICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMD 661

Query: 1088 G----TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G    +C+C  G+ G+ C   ++ C  +    G   ++    + C C +G   P C
Sbjct: 662  GINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSC 717



 Score =  111 bits (266), Expect = 5e-23
 Identities = 92/339 (27%), Positives = 137/339 (40%), Gaps = 48/339 (14%)

Query: 893  CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
            C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 131  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 190

Query: 947  -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEG-----TCVCKK 994
             C   G C+N     +C C +G+ G++C    + C    C   G C +       C C  
Sbjct: 191  HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 250

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV--CSLE---CG 1049
            G++G+ C     D         G     V+T  C C  +W+G+ C+++V  C L+   C 
Sbjct: 251  GFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310

Query: 1050 PHGRCV----GESCSCAAGWSGEFCSVRLCD---ARCAEHGQC----KNGTCLCVSGWNG 1098
              G C     G  C C  GWSG+ CS  + D   A C     C     + +C+C  G  G
Sbjct: 311  NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370

Query: 1099 RHCTLEGCPRSCAGHGQCRVDN---DGRWECKCFDGWDGPDCTTLKEQICDDSRDN---- 1151
              C L+    S   H     D    +G++ C C  G+ G DCT   ++ C  +  N    
Sbjct: 371  LLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDE-CAMANSNPCEH 429

Query: 1152 -----DKDGLVDCEDPECCQSPACKSS-QLCVSSPKPTD 1184
                 + DG   CE  +    P C+     C S P   D
Sbjct: 430  AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468



 Score =  107 bits (257), Expect = 6e-22
 Identities = 95/340 (27%), Positives = 129/340 (37%), Gaps = 47/340 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVLCSQ--RGEYING----ECQCNPG 929
            N C     C+ G     C C  G     C   V   L +    G    G    +C C+ G
Sbjct: 689  NPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAG 748

Query: 930  WKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCG-EID-CPHPTCSGHG 983
            W G  C +  +EC    C   G C   VNG +C+C +G+KG  C   ID C    C   G
Sbjct: 749  WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQG 808

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF----DVDTQTCSCHAKW 1034
             C +     TC C   + G +C T+      C P+ C          + ++ TC C   W
Sbjct: 809  TCFDDISGYTCHCVLPYTGKNCQTV---LAPCSPNPCENAAVCKESPNFESYTCLCAPGW 865

Query: 1035 SGEDCS---KEVCSLECGPHGRCVGES----CSCAAGWSGEFCSVRLCDA---RCAEHGQ 1084
             G+ C+    E  S  C  HG C        C C  G+SG  C   + D     C   G 
Sbjct: 866  QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGS 925

Query: 1085 CKNG----TCLCVSGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C +G    +CLC+ G+ G  C     E     C   G C  D    + CKC  G+DG  C
Sbjct: 926  CMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCS-DYVNSYTCKCQAGFDGVHC 984

Query: 1138 TTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
                 + C +S   +    VD  +   C  P   +   C+
Sbjct: 985  ENNINE-CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCL 1023



 Score =  105 bits (252), Expect = 2e-21
 Identities = 97/341 (28%), Positives = 135/341 (39%), Gaps = 62/341 (18%)

Query: 882  CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGW 930
            C   G C+      +CQC  G+ G  C + +  C     Q G    ++I G  C+C PG+
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179

Query: 931  KGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDCPH-PTCSGHG 983
            +G  C    DEC+   C   G C+    + KCSC  G +G  C E   DC   P C   G
Sbjct: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGG 1239

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD----VDTQTCSCHAKW 1034
             C++     +C C  G+ G  C   + D  +CL + CS  G+ D     +   C C + +
Sbjct: 1240 QCMDRIGGYSCRCLPGFAGERC---EGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296

Query: 1035 SGEDCSK--EVC-SLECGPHGRCV-------GESCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            +G  C    +VC  + C   G C        G  C C  G+SG  C       +C +  Q
Sbjct: 1297 TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQ 1356

Query: 1085 C----KNGTCLCVSGWNGRHCTLEGCPRS-CAGHGQCRVDND-GRWECKC---FDG---- 1131
            C        C C S    R C   GC  S C   G C        + C+C   F G    
Sbjct: 1357 CVHTASGPRCFCPS---PRDCE-SGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCE 1412

Query: 1132 -WDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACK 1171
             +  P  T     +     D  +DG+ D    E C S AC+
Sbjct: 1413 LYTAPPSTPPATCLSQYCADKARDGVCD----EACNSHACQ 1449



 Score =  101 bits (243), Expect = 3e-20
 Identities = 74/262 (28%), Positives = 104/262 (39%), Gaps = 33/262 (12%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKK 994
            C   G CV      G C C  G+ G++C   D C    C   G C+      + TC C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECG 1049
            G+ G DC             C   GT  +   DT  C+C   ++G++C   + C S  C 
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 1050 PHGRCVGE----SCSCAAGWSGEFC--SVRLCD--ARCAEHGQCKN--GT--CLCVSGWN 1097
                C       SC C  G++G+ C   V  CD    C   G C N  G+  C C  G+ 
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214

Query: 1098 GRHCT---LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKD 1154
            G++C    +   P  C   G CR   D  +EC C  G++G  C    +  C + R  +  
Sbjct: 215  GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDD-CPNHRCQNGG 273

Query: 1155 GLVDCEDPECCQSPACKSSQLC 1176
              VD  +   C+ P   + Q C
Sbjct: 274  VCVDGVNTYNCRCPPQWTGQFC 295



 Score = 98.7 bits (235), Expect = 3e-19
 Identities = 92/353 (26%), Positives = 135/353 (38%), Gaps = 58/353 (16%)

Query: 882  CSGKGECLM-----GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNP 928
            C  +G C+      G+C+C  GF G      D C K+ C     C  +       C+C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 929  GWKGKEC--SLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCS 980
            G+ G++C  S  H       C   G C        +C+C  G+ GK C   D C    C+
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 981  GHGFCI----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHA 1032
                C     + +C C  G+ G  C T   D  +C +P    HG   ++   +  C C  
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCPQ 211

Query: 1033 KWSGEDCSK---EVCSLECGPHGRC--VGE---SCSCAAGWSGEFCSVRLCDA---RCAE 1081
             ++G+ C           C   G C   G+    C+C  G+ G  C   + D    RC  
Sbjct: 212  GFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQN 271

Query: 1082 HGQCKNG----TCLCVSGWNGRHCT--LEGC---PRSCAGHGQCRVDNDGRWECKCFDGW 1132
             G C +G     C C   W G+ CT  ++ C   P +C   G C  + +G + C C +GW
Sbjct: 272  GGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC-ANRNGGYGCVCVNGW 330

Query: 1133 DGPDCTTLKEQIC-----DDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSP 1180
             G DC+   +          S   D+     C  PE      C     C+S+P
Sbjct: 331  SGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383



 Score = 97.1 bits (231), Expect = 9e-19
 Identities = 88/309 (28%), Positives = 125/309 (40%), Gaps = 53/309 (17%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 71   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 129

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 130  ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVD---TQ 1026
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT       T 
Sbjct: 189  P-GHCQHGGTCLNLPGSYQCQCPQGFTGQYC---DSLYVPCAPSPCVNGGTCRQTGDFTF 244

Query: 1027 TCSCHAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLC-- 1075
             C+C   + G  C + +  C +  C   G CV      +C C   W+G+FC+  V  C  
Sbjct: 245  ECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLL 304

Query: 1076 -DARCAEHGQC--KNG--TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKC 1128
                C   G C  +NG   C+CV+GW+G  C+  ++ C  +    G   +D    + C C
Sbjct: 305  QPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMC 364

Query: 1129 FDGWDGPDC 1137
             +G  G  C
Sbjct: 365  PEGKAGLLC 373



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 88/314 (28%), Positives = 125/314 (39%), Gaps = 61/314 (19%)

Query: 878  CPNGCSG-KGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C  G +G K +  M  C  +P   G  CS            +Y+N   C+C  G+ G  C
Sbjct: 937  CLPGFTGDKCQTDMNECLSEPCKNGGTCS------------DYVNSYTCKCQAGFDGVHC 984

Query: 936  SLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI-DCPHPTCSGHGFCIEG- 988
                +EC    C   G CV+G     C C  G+ G FC  EI +C    C   G C++G 
Sbjct: 985  ENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGL 1044

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF---DVDTQTCSCHAKWSGEDCSKE 1042
                C C  G+ G +C T+    L     C   GT      ++Q C C + W+G  C   
Sbjct: 1045 GTYRCSCPLGYTGKNCQTLVN--LCSRSPCKNKGTCVQKKAESQ-CLCPSGWAGAYCDVP 1101

Query: 1043 VCSLE-------------CGPHGRCVGES----CSCAAGWSGEFCSVRL--CDARCAEHG 1083
              S +             C   G C+       C C  G++G +C  +L  C +   +HG
Sbjct: 1102 NVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHG 1161

Query: 1084 -QCKN----GTCLCVSGWNGRHCTLE--GCP-RSCAGHGQCRVDNDGRWECKCFDGWDGP 1135
              C +      C CV G+ G +C  E   C  + C   G C +D    ++C C  G  G 
Sbjct: 1162 ATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC-IDLVNHFKCSCPPGTRGL 1220

Query: 1136 DCTTLKEQICDDSR 1149
             C   +E I D +R
Sbjct: 1221 LC---EENIDDCAR 1231



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 81/322 (25%), Positives = 112/322 (34%), Gaps = 60/322 (18%)

Query: 869  LVAEEMTHNCPNG--CSGKGECL--MG--HCQCQPGFGGDDCSKSVCPVL---CSQRGEY 919
            L+ EE   +C  G  C   G+C+  +G   C+C PGF G+ C   +   L   CS  G  
Sbjct: 1220 LLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSL 1279

Query: 920  ----INGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK-------CSCVRGYKG 966
                +  +  C C   + G+ C    D C    C   G C           C C  G+ G
Sbjct: 1280 DCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSG 1339

Query: 967  ----KFCGEI------DCPHPTCSGHGFC-----IEGTCVCKKGWKGADCGTMDKD---A 1008
                  CG++       C H       FC      E  C       G  C    +    +
Sbjct: 1340 ARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYS 1399

Query: 1009 LQCLPDCSGHG----TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG-RCVGESCSCAA 1063
             QC P  SG      T    T   +C +++  +     VC   C  H  +  G  CS   
Sbjct: 1400 CQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTM 1459

Query: 1064 GWSGEFCSVRL-C----DARCAEHGQCKNGTCLCVS---GWNGRHCTLEGCPRSCAGHGQ 1115
                  CS  L C    + +C E   C    CL  +     N + C  +   + CA H +
Sbjct: 1460 ENPWANCSSPLPCWDYINNQCDE--LCNTVECLFDNFECQGNSKTCKYD---KYCADHFK 1514

Query: 1116 CRVDNDGRWECKCFDGWDGPDC 1137
                N G    +C  GWDG DC
Sbjct: 1515 DNHCNQGCNSEEC--GWDGLDC 1534


>AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.
          Length = 1200

 Score =  130 bits (315), Expect = 6e-29
 Identities = 98/307 (31%), Positives = 134/307 (43%), Gaps = 37/307 (12%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS--QRGEYINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C ++VC   C+    G  + GEC+C+ GW+G+ C    DEC   P C
Sbjct: 227  GNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC----DECVPYPGC 282

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCIEG-----TCVCKKGWKG 998
              HG CV   +C+C   + G  C  +++ C  H  C+  G CI        C C  G+ G
Sbjct: 283  -VHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSG 341

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCS---KEVCSLECGPHGRC 1054
             +C   +  A    P  +G    +V +   C C + WSG  C+    E  S  C   G C
Sbjct: 342  RNCEKAE-HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTC 400

Query: 1055 V----GESCSCAAGWSGEFC--SVRLCDARCAEHGQCK---NG-TCLCVSGWNGRHCTLE 1104
            V    G  C C   W G  C   V  C  +C   G CK   NG  C+C  G+ GRHC LE
Sbjct: 401  VDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELE 460

Query: 1105 --GCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
               C  S C   G C    DG + C C  G+ GP C  +   +C+ S   +     + E 
Sbjct: 461  RDKCASSPCHSGGLCEDLADG-FHCHCPQGFSGPLC-EVDVDLCEPSPCRNGARCYNLEG 518

Query: 1162 PECCQSP 1168
               C  P
Sbjct: 519  DYYCACP 525



 Score =  118 bits (284), Expect = 3e-25
 Identities = 98/298 (32%), Positives = 123/298 (41%), Gaps = 54/298 (18%)

Query: 879  PNGCSGKGEC--LMG--HCQCQPGFGGDDCS--KSVCPVLCSQRGEYING-ECQCNPGWK 931
            P+ C     C  L G  +C C   FGG +CS  +  CP         I+G      PG  
Sbjct: 504  PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCP---GGACRVIDGCGSDAGPGMP 560

Query: 932  GKECSLRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGKFCGEI--DCPHPTCSGHGF 984
            G   S          C  HG CV     N  C C  G+ G +C E   DC    C   G 
Sbjct: 561  GTAAS--------GVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 612

Query: 985  CIEGT----CVCKKGWKGADCGTMDKDALQCLPD-CSGHGT-FD-VDTQTCSCHAKWSGE 1037
            CI+      C C  GW+G  C T   D   CLPD C   G  +D V+   C+C   W G+
Sbjct: 613  CIDEVDAFRCFCPSGWEGELCDTNPND---CLPDPCHSRGRCYDLVNDFYCACDDGWKGK 669

Query: 1038 DC-SKEV-C-SLECGPHGRCV--GES--CSCAAGWSGEFCSVRLCDA----RCAEHGQCK 1086
             C S+E  C +  C   G C   G++  C+C  GW G  C+V    +     C   G C 
Sbjct: 670  TCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCV 729

Query: 1087 NG----TCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                  +C+C  GW GR CT     C P  C   G C VD    + C+C  G+ GPDC
Sbjct: 730  GSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGIC-VDGVNWFRCECAPGFAGPDC 786



 Score =  109 bits (263), Expect = 1e-22
 Identities = 89/304 (29%), Positives = 116/304 (38%), Gaps = 47/304 (15%)

Query: 878  CPNGCSGKG------ECLMGHCQCQPGFGGD---DCSKSVCPVLCSQRGEYI-----NGE 923
            CP+   GK        C  G C+   G G D       +    +C   G  +     N  
Sbjct: 524  CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 583

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C C+ G+ G  C    D+C    C   G C++     +C C  G++G+ C     DC   
Sbjct: 584  CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 643

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC-LPDCSGHGT-FDV-DTQTCSC 1030
             C   G C +      C C  GWKG  C + +    QC    CS  GT +D  DT  C+C
Sbjct: 644  PCHSRGRCYDLVNDFYCACDDGWKGKTCHSRE---FQCDAYTCSNGGTCYDSGDTFRCAC 700

Query: 1031 HAKWSGEDCS--KEVCSLE--CGPHGRCVGE----SCSCAAGWSGEFCSVRLCDAR---C 1079
               W G  C+  K    L   C   G CVG     SC C  GW G  C+    D     C
Sbjct: 701  PPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPC 760

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
               G C +G     C C  G+ G  C   ++ C  S   +G   VD    + C C  G  
Sbjct: 761  YNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRA 820

Query: 1134 GPDC 1137
            GP C
Sbjct: 821  GPRC 824



 Score =  106 bits (254), Expect = 1e-21
 Identities = 98/330 (29%), Positives = 126/330 (38%), Gaps = 72/330 (21%)

Query: 876  HNCPNGCSGKGEC---LMGH-CQCQPGFGG-------DDCSKSVCPV--LCSQRGEYING 922
            ++C   C   G C   + G+ C C  GFGG       D C+ S C    LC    +  + 
Sbjct: 425  NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLADGFH- 483

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCG--EIDCPH 976
             C C  G+ G  C +  D CE   C     C N +    C+C   + GK C      CP 
Sbjct: 484  -CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPG 542

Query: 977  PTC-------------------SG----HGFCIEG-----TCVCKKGWKGADCGTMDKDA 1008
              C                   SG    HG C+       +C+C  G+ G  C     D 
Sbjct: 543  GACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDC 602

Query: 1009 LQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGPHGRC---VGES-C 1059
            L     C   GT   +VD   C C + W GE C      C  + C   GRC   V +  C
Sbjct: 603  LG--QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYC 660

Query: 1060 SCAAGWSGEFCSVR--LCDA-RCAEHGQCKNG----TCLCVSGWNGRHCTL---EGC-PR 1108
            +C  GW G+ C  R   CDA  C+  G C +      C C  GW G  C +     C P 
Sbjct: 661  ACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPN 720

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             C   G C V +   + C C DGW+G  CT
Sbjct: 721  PCVNGGTC-VGSGASFSCICRDGWEGRTCT 749



 Score = 93.5 bits (222), Expect = 1e-17
 Identities = 95/335 (28%), Positives = 134/335 (40%), Gaps = 42/335 (12%)

Query: 876  HNCPNGCSG-KGECLMGHCQCQPGFGGDDCSKS--VCPVL-CSQRG---EYING-ECQCN 927
            H C NG +    E     C C  G+ G +C K+   C    C+  G   E  +G EC C 
Sbjct: 315  HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP 374

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EIDCPHPTCSGH 982
             GW G  C+L  DEC    C   G CV+     +C C   + G  C  +++     C   
Sbjct: 375  SGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHG 434

Query: 983  GFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDV-DTQTCSCHAKWSGE 1037
            G C   + G  CVC +G+ G  C  +++D     P  SG    D+ D   C C   +SG 
Sbjct: 435  GTCKDLVNGYQCVCPRGFGGRHC-ELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGP 493

Query: 1038 DCSKEVCSLE---CGPHGRCV---GE-SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTC 1090
             C  +V   E   C    RC    G+  C+C   + G+ CSV            C  G C
Sbjct: 494  LCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSV--------PREPCPGGAC 545

Query: 1091 LCVSG-WNGRHCTLEGCPRS--CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDD 1147
              + G  +     + G   S  C  HG+C     G + C C  G+ G  C    E I D 
Sbjct: 546  RVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC---HENIDDC 602

Query: 1148 SRDNDKDG--LVDCEDPECCQSPACKSSQLCVSSP 1180
                 ++G   +D  D   C  P+    +LC ++P
Sbjct: 603  LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNP 637



 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 86/284 (30%), Positives = 118/284 (41%), Gaps = 49/284 (17%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRG---EYING-ECQCNPGW 930
            C NG +   E     C C  G+ G+ C  +   C P  C  RG   + +N   C C+ GW
Sbjct: 607  CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 666

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG---EIDC-PHPTCSGH 982
            KGK C  R  +C+   C+  G C +     +C+C  G+KG  C       C P+P C   
Sbjct: 667  KGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP-CVNG 725

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSGE 1037
            G C+      +C+C+ GW+G  C T + +    LP  +G    D V+   C C   ++G 
Sbjct: 726  GTCVGSGASFSCICRDGWEGRTC-THNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGP 784

Query: 1038 DCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFCSV-----RLCDARCA--EHG 1083
            DC     E  S  C     CV    G  CSC  G +G  C       R C +R     HG
Sbjct: 785  DCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHG 844

Query: 1084 -----QCKNGTCL-----CVSGWNG-RHCTLEGCPRSCAGHGQC 1116
                  C +  CL     C   W G + C L G P + +   QC
Sbjct: 845  SSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALS--AQC 886



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 52/185 (28%), Positives = 70/185 (37%), Gaps = 17/185 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH T D      +C   W G++C + VC   C   HG C V   C C+ GW 
Sbjct: 211  CRPRNDFFGHYTCD-QYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQ 269

Query: 1067 GEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G FC   +    C  HG C +   C C + W G  C  +    G    C   G C     
Sbjct: 270  GRFCDECVPYPGCV-HGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEP 328

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACK-SSQL 1175
             ++ C C DG+ G +C   +     +   N     +     +C  P     P C      
Sbjct: 329  DQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDE 388

Query: 1176 CVSSP 1180
            C S+P
Sbjct: 389  CASNP 393


>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
          Length = 1235

 Score =  129 bits (312), Expect = 1e-28
 Identities = 93/301 (30%), Positives = 130/301 (43%), Gaps = 47/301 (15%)

Query: 880  NGCSGKGEC---LMGH-CQCQPGFGGDDCSKSVCP---------VLCSQRGEYINGECQC 926
            N C  +G C   + G+ C C   + G +C   + P          +C +   + +  C C
Sbjct: 802  NPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLC 861

Query: 927  NPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGE--IDCPHPTCS 980
             PGW+G+ C++  DEC    C  HG C N +    C C  G+ G  C E   DC    C 
Sbjct: 862  APGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQ 921

Query: 981  GHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD--VDTQTCSCHAK 1033
              G C++G    +C+C  G+ G    T   D  +CL + C   GT    V++ TC C A 
Sbjct: 922  NGGSCMDGVNTFSCLCLPGFTGDKYQT---DMNECLSEPCKNGGTCSDYVNSYTCKCQAG 978

Query: 1034 WSGEDCSKEV--CS-LECGPHGRCV----GESCSCAAGWSGEFC--SVRLCDAR-CAEHG 1083
            + G  C   +  C+   C   G CV      SC C  G++G FC   +  C +  C   G
Sbjct: 979  FDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEG 1038

Query: 1084 QCKNG----TCLCVSGWNGRHC-TLEG-CPRS-CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
             C +G     C C  G+ G++C TL   C RS C   G C V      +C C  GW G  
Sbjct: 1039 TCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC-VQKKAESQCLCPSGWAGAY 1097

Query: 1137 C 1137
            C
Sbjct: 1098 C 1098



 Score =  124 bits (298), Expect = 6e-27
 Identities = 95/322 (29%), Positives = 132/322 (40%), Gaps = 45/322 (13%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
            ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 149  LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 208

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGE--IDCPHPT 978
            C  G+ G+ C   +  C    C   G C        +C+C+ G++G  C     DCP+  
Sbjct: 209  CPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR 268

Query: 979  CSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDT--QTCSCH 1031
            C   G C++G     C C   W G  C T D D     P+ C   GT         C C 
Sbjct: 269  CQNGGVCVDGVNTYNCRCPPQWTGQFC-TEDVDECLLQPNACQNGGTCANRNGGYGCVCV 327

Query: 1032 AKWSGEDCSKEV--CSL-ECGPHGRCVGE----SCSCAAGWSGEFCSV-RLCDAR-CAEH 1082
              WSG+DCS+ +  C+   C P   C+      SC C  G +G  C +   C +  C + 
Sbjct: 328  NGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKG 387

Query: 1083 GQCK----NG--TCLCVSGWNGRHCT--LEGCPRS----CAGHGQCRVDNDGRWECKCFD 1130
              C     NG   C C  G+ G  CT  ++ C  +    C   G+C V+ DG + C+C  
Sbjct: 388  ALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKC-VNTDGAFHCECLK 446

Query: 1131 GWDGPDCTTLKEQICDDSRDND 1152
            G+ GP C     +   D   ND
Sbjct: 447  GYAGPRCEMDINECHSDPCQND 468



 Score =  117 bits (281), Expect = 7e-25
 Identities = 86/296 (29%), Positives = 127/296 (42%), Gaps = 41/296 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNP 928
            N C   G+C+      HC+C  G+ G  C   +  C     Q      + I G  C C P
Sbjct: 425  NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP 484

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EI-DCPHPTCSGH 982
            G+KG  C L  +EC+   C  +G CV+     +C C  G+ G  C  +I DC    C   
Sbjct: 485  GFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNG 544

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSG 1036
              CI+      C C  G+ G  C   +++   C PD   HG     +D+ TC C+  + G
Sbjct: 545  AKCIDHPNGYECQCATGFTGVLC---EENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMG 601

Query: 1037 EDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDARCAEHGQCKN 1087
              CS ++  C S  C   GRC+    G  C+C  G SG  C +    C +    HG C +
Sbjct: 602  AICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMD 661

Query: 1088 G----TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G    +C+C  G+ G+ C   ++ C  +    G   ++    + C C +G   P C
Sbjct: 662  GINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSC 717



 Score =  113 bits (272), Expect = 9e-24
 Identities = 87/290 (30%), Positives = 122/290 (42%), Gaps = 47/290 (16%)

Query: 893  CQCQPGFGGDDCSKSVCPVL---CSQRGEYING----ECQCNPGWKGKECSLRHDECEVP 945
            C+C PGF G DC + +   L   C   G  ++G     C C PG+ G +     +EC   
Sbjct: 897  CECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQTDMNECLSE 956

Query: 946  DCNGHGHC---VNG-KCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEG----TCVCKKG 995
             C   G C   VN   C C  G+ G  C     +C   +C   G C++G    +C+C  G
Sbjct: 957  PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVG 1016

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGP 1050
            + G+ C   + +     P C   GT    + T  CSC   ++G++C   V  CS   C  
Sbjct: 1017 FTGSFC-LHEINECSSHP-CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKN 1074

Query: 1051 HGRCV---GES-CSCAAGWSGEFCSVR--LCDAR-----------CAEHGQCKNGT---- 1089
             G CV    ES C C +GW+G +C V    CD             C   G C N      
Sbjct: 1075 KGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHY 1134

Query: 1090 CLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C C  G+ G +C   L+ C  +   HG    D  G + C+C  G+ G +C
Sbjct: 1135 CQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNC 1184



 Score =  111 bits (266), Expect = 5e-23
 Identities = 92/339 (27%), Positives = 137/339 (40%), Gaps = 48/339 (14%)

Query: 893  CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
            C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 131  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 190

Query: 947  -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEG-----TCVCKK 994
             C   G C+N     +C C +G+ G++C    + C    C   G C +       C C  
Sbjct: 191  HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLP 250

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV--CSLE---CG 1049
            G++G+ C     D         G     V+T  C C  +W+G+ C+++V  C L+   C 
Sbjct: 251  GFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310

Query: 1050 PHGRCV----GESCSCAAGWSGEFCSVRLCD---ARCAEHGQC----KNGTCLCVSGWNG 1098
              G C     G  C C  GWSG+ CS  + D   A C     C     + +C+C  G  G
Sbjct: 311  NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370

Query: 1099 RHCTLEGCPRSCAGHGQCRVDN---DGRWECKCFDGWDGPDCTTLKEQICDDSRDN---- 1151
              C L+    S   H     D    +G++ C C  G+ G DCT   ++ C  +  N    
Sbjct: 371  LLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDE-CAMANSNPCEH 429

Query: 1152 -----DKDGLVDCEDPECCQSPACKSS-QLCVSSPKPTD 1184
                 + DG   CE  +    P C+     C S P   D
Sbjct: 430  AGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND 468



 Score =  104 bits (249), Expect = 6e-21
 Identities = 95/340 (27%), Positives = 132/340 (38%), Gaps = 47/340 (13%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVLCSQ--RGEYING----ECQCNPG 929
            N C     C+ G     C C  G     C   V   L +    G    G    +C C+ G
Sbjct: 689  NPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAG 748

Query: 930  WKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCG-EID-CPHPTCSGHG 983
            W G  C +  +EC    C   G C   VNG +C+C +G+KG  C   ID C    C   G
Sbjct: 749  WVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQG 808

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF----DVDTQTCSCHAKW 1034
             C +     TC C   + G +C T+      C P+ C          + ++ TC C   W
Sbjct: 809  TCFDDISGYTCHCVLPYTGKNCQTV---LAPCSPNPCENAAVCKESPNFESYTCLCAPGW 865

Query: 1035 SGEDCS---KEVCSLECGPHGRCVGES----CSCAAGWSGEFCSVRLCDA---RCAEHGQ 1084
             G+ C+    E  S  C  HG C        C C  G+SG  C   + D     C   G 
Sbjct: 866  QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGS 925

Query: 1085 CKNG----TCLCVSGWNG-RHCT-LEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C +G    +CLC+ G+ G ++ T +  C    C   G C  D    + CKC  G+DG  C
Sbjct: 926  CMDGVNTFSCLCLPGFTGDKYQTDMNECLSEPCKNGGTCS-DYVNSYTCKCQAGFDGVHC 984

Query: 1138 TTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCV 1177
                 + C +S   +    VD  +   C  P   +   C+
Sbjct: 985  ENNINE-CTESSCFNGGTCVDGINSFSCLCPVGFTGSFCL 1023



 Score =  104 bits (249), Expect = 6e-21
 Identities = 99/358 (27%), Positives = 148/358 (41%), Gaps = 49/358 (13%)

Query: 863  EISFVALVAEEMTHNC-PNGCSGKGEC---LMGH-CQCQPGFGGDDCSKSVCPVL---CS 914
            +  +V +  E   + C  N C   G C   + G+ C C+ GF G +C  ++       C 
Sbjct: 746  DAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCL 805

Query: 915  QRG---EYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK------CSCVRGY 964
             +G   + I+G  C C   + GK C      C    C     C          C C  G+
Sbjct: 806  NQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGW 865

Query: 965  KGKFCG-EID-CPHPTCSGHGFC--IEGT--CVCKKGWKGADCGTMDKDALQCLPD-CSG 1017
            +G+ C  +ID C    C  HG C   +G+  C C  G+ G DC   ++D   CL + C  
Sbjct: 866  QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDC---EEDIDDCLANPCQN 922

Query: 1018 HGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGPHGRCV----GESCSCAAGWSGE 1068
             G+    V+T +C C   ++G+    ++  C  E C   G C       +C C AG+ G 
Sbjct: 923  GGSCMDGVNTFSCLCLPGFTGDKYQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGV 982

Query: 1069 FC--SVRLC-DARCAEHGQCKNG----TCLCVSGWNGRHCTLE--GCP-RSCAGHGQCRV 1118
             C  ++  C ++ C   G C +G    +CLC  G+ G  C  E   C    C   G C V
Sbjct: 983  HCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTC-V 1041

Query: 1119 DNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
            D  G + C C  G+ G +C TL   +C  S   +K   V  +    C  P+  +   C
Sbjct: 1042 DGLGTYRCSCPLGYTGKNCQTL-VNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098



 Score =  101 bits (243), Expect = 3e-20
 Identities = 74/262 (28%), Positives = 104/262 (39%), Gaps = 33/262 (12%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKK 994
            C   G CV      G C C  G+ G++C   D C    C   G C+      + TC C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECG 1049
            G+ G DC             C   GT  +   DT  C+C   ++G++C   + C S  C 
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 1050 PHGRCVGE----SCSCAAGWSGEFC--SVRLCD--ARCAEHGQCKN--GT--CLCVSGWN 1097
                C       SC C  G++G+ C   V  CD    C   G C N  G+  C C  G+ 
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214

Query: 1098 GRHCT---LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKD 1154
            G++C    +   P  C   G CR   D  +EC C  G++G  C    +  C + R  +  
Sbjct: 215  GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDD-CPNHRCQNGG 273

Query: 1155 GLVDCEDPECCQSPACKSSQLC 1176
              VD  +   C+ P   + Q C
Sbjct: 274  VCVDGVNTYNCRCPPQWTGQFC 295



 Score = 98.7 bits (235), Expect = 3e-19
 Identities = 92/353 (26%), Positives = 135/353 (38%), Gaps = 58/353 (16%)

Query: 882  CSGKGECLM-----GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNP 928
            C  +G C+      G+C+C  GF G      D C K+ C     C  +       C+C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 929  GWKGKEC--SLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCS 980
            G+ G++C  S  H       C   G C        +C+C  G+ GK C   D C    C+
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 981  GHGFCI----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHA 1032
                C     + +C C  G+ G  C T   D  +C +P    HG   ++   +  C C  
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCPQ 211

Query: 1033 KWSGEDCSK---EVCSLECGPHGRC--VGE---SCSCAAGWSGEFCSVRLCDA---RCAE 1081
             ++G+ C           C   G C   G+    C+C  G+ G  C   + D    RC  
Sbjct: 212  GFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQN 271

Query: 1082 HGQCKNG----TCLCVSGWNGRHCT--LEGC---PRSCAGHGQCRVDNDGRWECKCFDGW 1132
             G C +G     C C   W G+ CT  ++ C   P +C   G C  + +G + C C +GW
Sbjct: 272  GGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC-ANRNGGYGCVCVNGW 330

Query: 1133 DGPDCTTLKEQIC-----DDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSP 1180
             G DC+   +          S   D+     C  PE      C     C+S+P
Sbjct: 331  SGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383



 Score = 97.1 bits (231), Expect = 9e-19
 Identities = 88/309 (28%), Positives = 125/309 (40%), Gaps = 53/309 (17%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 71   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 129

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 130  ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVD---TQ 1026
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT       T 
Sbjct: 189  P-GHCQHGGTCLNLPGSYQCQCPQGFTGQYC---DSLYVPCAPSPCVNGGTCRQTGDFTF 244

Query: 1027 TCSCHAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLC-- 1075
             C+C   + G  C + +  C +  C   G CV      +C C   W+G+FC+  V  C  
Sbjct: 245  ECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLL 304

Query: 1076 -DARCAEHGQC--KNG--TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKC 1128
                C   G C  +NG   C+CV+GW+G  C+  ++ C  +    G   +D    + C C
Sbjct: 305  QPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMC 364

Query: 1129 FDGWDGPDC 1137
             +G  G  C
Sbjct: 365  PEGKAGLLC 373



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 15/100 (15%)

Query: 882  CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGW 930
            C   G C+      +CQC  G+ G  C + +  C     Q G    ++I G  C+C PG+
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179

Query: 931  KGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKG 966
            +G  C    DEC+   C   G C+    + KCSC  G +G
Sbjct: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRG 1219


>AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.
          Length = 1238

 Score =  122 bits (294), Expect = 2e-26
 Identities = 95/315 (30%), Positives = 132/315 (41%), Gaps = 37/315 (11%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS--QRGEYINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C ++VC   C+    G  + GEC+C+ GW+G+ C    DEC   P C
Sbjct: 227  GNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC----DECVPYPGC 282

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCIEG-----TCVCKKGWKG 998
              HG CV   +C+C   + G  C  +++ C  H  C+  G CI        C C  G+ G
Sbjct: 283  -VHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSG 341

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCS---KEVCSLECGPHGRC 1054
             +C   +  A    P  +G    +V +   C C + WSG  C+    E  S  C   G C
Sbjct: 342  RNCEKAE-HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTC 400

Query: 1055 V----GESCSCAAGWSGEFC--SVRLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC-- 1101
            V    G  C C   W G  C   V  C+ + C     CKN      C C+ GW G +C  
Sbjct: 401  VDQVDGFECICPEQWVGATCQLDVNDCEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHI 460

Query: 1102 TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
             +  C   C   G C+ D    ++C C  G+ G  C  L+   C  S  +      D  D
Sbjct: 461  NVNDCRGQCQHGGTCK-DLVNGYQCVCPRGFGGRHC-ELERDKCASSPCHSGGLCEDLAD 518

Query: 1162 PECCQSPACKSSQLC 1176
               C  P   S  LC
Sbjct: 519  GFHCHCPQGFSGPLC 533



 Score =  109 bits (263), Expect = 1e-22
 Identities = 89/304 (29%), Positives = 116/304 (38%), Gaps = 47/304 (15%)

Query: 878  CPNGCSGKG------ECLMGHCQCQPGFGGD---DCSKSVCPVLCSQRGEYI-----NGE 923
            CP+   GK        C  G C+   G G D       +    +C   G  +     N  
Sbjct: 562  CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C C+ G+ G  C    D+C    C   G C++     +C C  G++G+ C     DC   
Sbjct: 622  CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC-LPDCSGHGT-FDV-DTQTCSC 1030
             C   G C +      C C  GWKG  C + +    QC    CS  GT +D  DT  C+C
Sbjct: 682  PCHSRGRCYDLVNDFYCACDDGWKGKTCHSRE---FQCDAYTCSNGGTCYDSGDTFRCAC 738

Query: 1031 HAKWSGEDC--SKEVCSL--ECGPHGRCVGE----SCSCAAGWSGEFCSVRLCDAR---C 1079
               W G  C  +K    L   C   G CVG     SC C  GW G  C+    D     C
Sbjct: 739  PPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPC 798

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
               G C +G     C C  G+ G  C   ++ C  S   +G   VD    + C C  G  
Sbjct: 799  YNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRA 858

Query: 1134 GPDC 1137
            GP C
Sbjct: 859  GPRC 862



 Score =  106 bits (254), Expect = 1e-21
 Identities = 98/330 (29%), Positives = 126/330 (38%), Gaps = 72/330 (21%)

Query: 876  HNCPNGCSGKGEC---LMGH-CQCQPGFGG-------DDCSKSVCPV--LCSQRGEYING 922
            ++C   C   G C   + G+ C C  GFGG       D C+ S C    LC    +  + 
Sbjct: 463  NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLADGFH- 521

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCG--EIDCPH 976
             C C  G+ G  C +  D CE   C     C N +    C+C   + GK C      CP 
Sbjct: 522  -CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPG 580

Query: 977  PTC-------------------SG----HGFCIEG-----TCVCKKGWKGADCGTMDKDA 1008
              C                   SG    HG C+       +C+C  G+ G  C     D 
Sbjct: 581  GACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDC 640

Query: 1009 LQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGPHGRC---VGES-C 1059
            L     C   GT   +VD   C C + W GE C      C  + C   GRC   V +  C
Sbjct: 641  LG--QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYC 698

Query: 1060 SCAAGWSGEFCSVR--LCDA-RCAEHGQCKNG----TCLCVSGWNGRHCTL---EGC-PR 1108
            +C  GW G+ C  R   CDA  C+  G C +      C C  GW G  C +     C P 
Sbjct: 699  ACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPN 758

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             C   G C V +   + C C DGW+G  CT
Sbjct: 759  PCVNGGTC-VGSGASFSCICRDGWEGRTCT 787



 Score =   99 bits (238), Expect = 1e-19
 Identities = 89/326 (27%), Positives = 124/326 (38%), Gaps = 60/326 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRG---EYING-ECQCNPGWK 931
            C N  S K      +C C PG+ G +C  +V  C   C   G   + +NG +C C  G+ 
Sbjct: 432  CLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFG 491

Query: 932  GKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGEID---CPHPTCSGHGF 984
            G+ C L  D+C    C+  G C    +G  C C +G+ G  C E+D   C    C     
Sbjct: 492  GRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLC-EVDVDLCEPSPCRNGAR 550

Query: 985  C--IEGT--CVCKKGWKGADCGT---------------MDKDALQCLPD------CSGHG 1019
            C  +EG   C C   + G +C                    DA   +P       C  HG
Sbjct: 551  CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHG 610

Query: 1020 ---TFDVDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVGE----SCSCAAGWSGEF 1069
               +      +C C + ++G  C + +  C    C   G C+ E     C C +GW GE 
Sbjct: 611  RCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGEL 670

Query: 1070 CSVRLCDAR---CAEHGQC----KNGTCLCVSGWNGRHCTLEG--CPR-SCAGHGQCRVD 1119
            C     D     C   G+C     +  C C  GW G+ C      C   +C+  G C  D
Sbjct: 671  CDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTC-YD 729

Query: 1120 NDGRWECKCFDGWDGPDCTTLKEQIC 1145
            +   + C C  GW G  C   K   C
Sbjct: 730  SGDTFRCACPPGWKGSTCAVAKNSSC 755



 Score = 96.3 bits (229), Expect = 1e-18
 Identities = 105/367 (28%), Positives = 137/367 (37%), Gaps = 68/367 (18%)

Query: 876  HNCPNGCSG-KGECLMGHCQCQPGFGGDDCSKS--VCPVL-CSQRG---EYING-ECQCN 927
            H C NG +    E     C C  G+ G +C K+   C    C+  G   E  +G EC C 
Sbjct: 315  HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP 374

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSG 981
             GW G  C+L  DEC    C   G CV+     +C C   + G  C     DC    C  
Sbjct: 375  SGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCEGKPCLN 434

Query: 982  HGFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWS 1035
               C   I G  C C  GWKG +C     D   C   C   GT    V+   C C   + 
Sbjct: 435  AFSCKNLIGGYYCDCIPGWKGINCHINVND---CRGQCQHGGTCKDLVNGYQCVCPRGFG 491

Query: 1036 GEDCSKE---VCSLECGPHGRCV----GESCSCAAGWSGEFC--SVRLCD-ARCAEHGQC 1085
            G  C  E     S  C   G C     G  C C  G+SG  C   V LC+ + C    +C
Sbjct: 492  GRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARC 551

Query: 1086 KN--GT--CLCVSGWNGRHCTL--EGCPRS------------------------CAGHGQ 1115
             N  G   C C   + G++C++  E CP                          C  HG+
Sbjct: 552  YNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGR 611

Query: 1116 CRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG--LVDCEDPECCQSPACKSS 1173
            C     G + C C  G+ G  C    E I D      ++G   +D  D   C  P+    
Sbjct: 612  CVSQPGGNFSCICDSGFTGTYC---HENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEG 668

Query: 1174 QLCVSSP 1180
            +LC ++P
Sbjct: 669  ELCDTNP 675



 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 86/284 (30%), Positives = 118/284 (41%), Gaps = 49/284 (17%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRG---EYING-ECQCNPGW 930
            C NG +   E     C C  G+ G+ C  +   C P  C  RG   + +N   C C+ GW
Sbjct: 645  CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 704

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG---EIDC-PHPTCSGH 982
            KGK C  R  +C+   C+  G C +     +C+C  G+KG  C       C P+P C   
Sbjct: 705  KGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP-CVNG 763

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSGE 1037
            G C+      +C+C+ GW+G  C T + +    LP  +G    D V+   C C   ++G 
Sbjct: 764  GTCVGSGASFSCICRDGWEGRTC-THNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGP 822

Query: 1038 DCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFCSV-----RLCDARCA--EHG 1083
            DC     E  S  C     CV    G  CSC  G +G  C       R C +R     HG
Sbjct: 823  DCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHG 882

Query: 1084 -----QCKNGTCL-----CVSGWNG-RHCTLEGCPRSCAGHGQC 1116
                  C +  CL     C   W G + C L G P + +   QC
Sbjct: 883  SSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALS--AQC 924



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 52/185 (28%), Positives = 70/185 (37%), Gaps = 17/185 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH T D      +C   W G++C + VC   C   HG C V   C C+ GW 
Sbjct: 211  CRPRNDFFGHYTCD-QYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQ 269

Query: 1067 GEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G FC   +    C  HG C +   C C + W G  C  +    G    C   G C     
Sbjct: 270  GRFCDECVPYPGCV-HGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEP 328

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACK-SSQL 1175
             ++ C C DG+ G +C   +     +   N     +     +C  P     P C      
Sbjct: 329  DQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDE 388

Query: 1176 CVSSP 1180
            C S+P
Sbjct: 389  CASNP 393


>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
            protein.
          Length = 1214

 Score =  121 bits (292), Expect = 3e-26
 Identities = 101/333 (30%), Positives = 129/333 (38%), Gaps = 68/333 (20%)

Query: 870  VAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE--- 923
            + E  ++ C NG   + E     C C  GF G+ C   +  C P  C    +  N     
Sbjct: 475  IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDY 534

Query: 924  -CQCNPGWKGKECS-----LRHDECEVPD----------------------CNGHGHCVN 955
             C+C   ++GK CS      R   CEV D                      C  HG C +
Sbjct: 535  FCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 594

Query: 956  ---GK--CSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTM 1004
               GK  C C +G+ G +C E   DC    C   G CI+G     C+C  GW+GA C T 
Sbjct: 595  QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN 654

Query: 1005 DKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGEDC---SKEVCSLECGPHGRCVGE-- 1057
              D  Q    C   GT    V+   C C   W G+ C     +     C   G C  E  
Sbjct: 655  INDCSQ--NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD 712

Query: 1058 --SCSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNG---TCLCVSGWNGRHC---TLE 1104
               C C  GW G  C++    +     C   G C  NG   TC+C  GW G  C   T +
Sbjct: 713  AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND 772

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              P  C   G C VD D  + C+C  G+ GPDC
Sbjct: 773  CSPHPCYNSGTC-VDGDNWYRCECAPGFAGPDC 804



 Score =  120 bits (290), Expect = 6e-26
 Identities = 89/293 (30%), Positives = 118/293 (40%), Gaps = 37/293 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GCS K G C L G C+CQ G+ G  C K +    C         +C C   W G+ C
Sbjct: 221  CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLC 280

Query: 936  SLRHDECEV-PDCNGHGHCVNG-----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
                + C     C   G C N      +CSC  GY G  C   E  C    C   G C E
Sbjct: 281  DKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKE 340

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS 1040
             +    C C  GW G  C T   D   C P +CS  GT    V+   C C  +W+G+ C 
Sbjct: 341  TSLGFECECSPGWTGPTCSTNIDD---CSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ 397

Query: 1041 KEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL--CDARCAEHGQCK---NG 1088
             +    E  P               C C  GW G+ C + +  C  +C     C+   NG
Sbjct: 398  LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG 457

Query: 1089 -TCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+C  G+ G HC   ++ C  + C   G C+ +   R++C C  G+ G  C
Sbjct: 458  YRCICPPGYAGDHCERDIDECASNPCLNGGHCQ-NEINRFQCLCPTGFSGNLC 509



 Score =  115 bits (277), Expect = 2e-24
 Identities = 86/270 (31%), Positives = 114/270 (42%), Gaps = 36/270 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + G  C+K  C       G Y    NG   C  GW G EC+     C       HG
Sbjct: 174  CDDYYYGFGCNK-FCRPRDDFFGHYACDQNGNKTCMEGWMGPECN--RAICRQGCSPKHG 230

Query: 952  HC-VNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL 1009
             C + G C C  G++G +C +   PHP C  HG C E   C+C+  W G  C   DKD  
Sbjct: 231  SCKLPGDCRCQYGWQGLYCDKC-IPHPGCV-HGICNEPWQCLCETNWGGQLC---DKDLN 285

Query: 1010 QC--LPDCSGHGTFD---VDTQTCSCHAKWSGEDC--SKEVC-SLECGPHGRC----VGE 1057
             C     C   GT      D   CSC   +SG +C  ++  C S  C   G C    +G 
Sbjct: 286  YCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGF 345

Query: 1058 SCSCAAGWSGEFCSVRLCDA---RCAEHGQCK---NG-TCLCVSGWNGRHCTLEG--C-P 1107
             C C+ GW+G  CS  + D     C+  G C+   NG  C+C   W G+ C L+   C  
Sbjct: 346  ECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 405

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            + C     C+ +    + C C  GW G +C
Sbjct: 406  KPCVNAKSCK-NLIASYYCDCLPGWMGQNC 434



 Score =  113 bits (273), Expect = 7e-24
 Identities = 85/291 (29%), Positives = 108/291 (37%), Gaps = 36/291 (12%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C CN G+ G  C    ++CE   C   G C++G    KC C  G++G +C     DC   
Sbjct: 602  CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN 661

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGT-FDV-DTQTCSCH 1031
             C   G C +      C CK GWKG  C + D    +    C+  GT +D  D   C C 
Sbjct: 662  PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA--TCNNGGTCYDEGDAFKCMCP 719

Query: 1032 AKWSGEDC----SKEVCSLECGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CA 1080
              W G  C    +       C   G CV  GES  C C  GW G  C+    D     C 
Sbjct: 720  GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCY 779

Query: 1081 EHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
              G C +G     C C  G+ G  C   +  C  S    G   VD    + C C  G  G
Sbjct: 780  NSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSG 839

Query: 1135 PDCTTLKEQICDDSRDNDKDGLV---DCEDPECCQSPACKSSQLCVSSPKP 1182
              C  +  + C        DG     DC   +C       S   C   P+P
Sbjct: 840  AKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWC--GPRP 888



 Score =  104 bits (250), Expect = 4e-21
 Identities = 81/278 (29%), Positives = 120/278 (43%), Gaps = 40/278 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS-QRGE-YINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C++++C   CS + G   + G+C+C  GW+G  C    D+C   P C
Sbjct: 203  GNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYC----DKCIPHPGC 258

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCI-----EGTCVCKKGWKG 998
              HG C    +C C   + G+ C  +++ C  H  C   G C      +  C C +G+ G
Sbjct: 259  -VHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG 317

Query: 999  ADCGTMDKDALQCLPD-CSGHGTFDVDTQ--TCSCHAKWSGEDCSKEV--CS-LECGPHG 1052
             +C   +     CL D C   G+    +    C C   W+G  CS  +  CS   C   G
Sbjct: 318  PNCEIAEH---ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 374

Query: 1053 RCV----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC 1101
             C     G  C C   W+G+ C +    C+A+ C     CKN      C C+ GW G++C
Sbjct: 375  TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 434

Query: 1102 --TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
               +  C   C     CR D    + C C  G+ G  C
Sbjct: 435  DININDCLGQCQNDASCR-DLVNGYRCICPPGYAGDHC 471



 Score =  104 bits (249), Expect = 6e-21
 Identities = 80/263 (30%), Positives = 107/263 (40%), Gaps = 38/263 (14%)

Query: 875  THN-CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGEY----INGEC 924
            TH  C NG  CS  G      C C  G+ G +C  +    L   C  RG      +  EC
Sbjct: 289  THQPCLNGGTCSNTGPDKY-QCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC 347

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPT 978
            +C+PGW G  CS   D+C   +C+  G C   VNG KC C   + GK C     +C    
Sbjct: 348  ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP 407

Query: 979  CSGHGFC----IEGTCVCKKGWKGADCGTMDKDAL-QCLPDCSGHGTFDVDTQTCSCHAK 1033
            C     C        C C  GW G +C     D L QC  D S      V+   C C   
Sbjct: 408  CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDL--VNGYRCICPPG 465

Query: 1034 WSGEDCSKEV---CSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHG 1083
            ++G+ C +++    S  C   G C  E     C C  G+SG  C + +  C+   C    
Sbjct: 466  YAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGA 525

Query: 1084 QCKNGT----CLCVSGWNGRHCT 1102
            QC N      C C   + G++C+
Sbjct: 526  QCYNRASDYFCKCPEDYEGKNCS 548



 Score =  101 bits (242), Expect = 4e-20
 Identities = 93/295 (31%), Positives = 116/295 (39%), Gaps = 48/295 (16%)

Query: 866  FVALVAEEMTHNCP-NGCSGKGECLMG----HCQCQPGFGG-------DDCSKSVCPVLC 913
            F      E  ++C  N C   G C+ G     C C  G+ G       +DCS++ C    
Sbjct: 608  FTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGG 667

Query: 914  SQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC 969
            + R    +  C C  GWKGK C  R  +C+   CN  G C +     KC C  G++G  C
Sbjct: 668  TCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTC 727

Query: 970  G---EIDC-PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLP-DCSGHGT 1020
                   C P+P C   G C+      TCVCK+GW+G  C     D   C P  C   GT
Sbjct: 728  NIARNSSCLPNP-CHNGGTCVVNGESFTCVCKEGWEGPICAQNTND---CSPHPCYNSGT 783

Query: 1021 -FDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFC- 1070
              D D    C C   ++G DC     E  S  C     CV    G  C C  G SG  C 
Sbjct: 784  CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 843

Query: 1071 --SVRLC--DARCAEHGQCKNGTCLCVSGWNGR-HCTLEGC-PRSC---AGHGQC 1116
              S R C         G   +  C      NGR  C+   C PR C    GH +C
Sbjct: 844  EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSEC 898



 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 16/177 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH   D +    +C   W G +C++ +C   C P HG C +   C C  GW 
Sbjct: 187  CRPRDDFFGHYACDQNGNK-TCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQ 245

Query: 1067 GEFCSVRLCDARCAEHGQCKNG-TCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G +C   +    C  HG C     CLC + W G+ C  +    G  + C   G C     
Sbjct: 246  GLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGP 304

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDD---SRDNDKDGLV--DCEDPECCQSPACKSS 1173
             +++C C +G+ GP+C   +     D   +R + K+  +  +CE       P C ++
Sbjct: 305  DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTN 361


>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
          Length = 1218

 Score =  121 bits (292), Expect = 3e-26
 Identities = 101/333 (30%), Positives = 129/333 (38%), Gaps = 68/333 (20%)

Query: 870  VAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE--- 923
            + E  ++ C NG   + E     C C  GF G+ C   +  C P  C    +  N     
Sbjct: 488  IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDY 547

Query: 924  -CQCNPGWKGKECS-----LRHDECEVPD----------------------CNGHGHCVN 955
             C+C   ++GK CS      R   CEV D                      C  HG C +
Sbjct: 548  FCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607

Query: 956  ---GK--CSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTM 1004
               GK  C C +G+ G +C E   DC    C   G CI+G     C+C  GW+GA C T 
Sbjct: 608  QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN 667

Query: 1005 DKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGEDC---SKEVCSLECGPHGRCVGE-- 1057
              D  Q    C   GT    V+   C C   W G+ C     +     C   G C  E  
Sbjct: 668  INDCSQ--NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD 725

Query: 1058 --SCSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNG---TCLCVSGWNGRHC---TLE 1104
               C C  GW G  C++    +     C   G C  NG   TC+C  GW G  C   T +
Sbjct: 726  AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND 785

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              P  C   G C VD D  + C+C  G+ GPDC
Sbjct: 786  CSPHPCYNSGTC-VDGDNWYRCECAPGFAGPDC 817



 Score =  120 bits (290), Expect = 6e-26
 Identities = 89/293 (30%), Positives = 118/293 (40%), Gaps = 37/293 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GCS K G C L G C+CQ G+ G  C K +    C         +C C   W G+ C
Sbjct: 234  CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLC 293

Query: 936  SLRHDECEV-PDCNGHGHCVNG-----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
                + C     C   G C N      +CSC  GY G  C   E  C    C   G C E
Sbjct: 294  DKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKE 353

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS 1040
             +    C C  GW G  C T   D   C P +CS  GT    V+   C C  +W+G+ C 
Sbjct: 354  TSLGFECECSPGWTGPTCSTNIDD---CSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ 410

Query: 1041 KEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL--CDARCAEHGQCK---NG 1088
             +    E  P               C C  GW G+ C + +  C  +C     C+   NG
Sbjct: 411  LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG 470

Query: 1089 -TCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+C  G+ G HC   ++ C  + C   G C+ +   R++C C  G+ G  C
Sbjct: 471  YRCICPPGYAGDHCERDIDECASNPCLNGGHCQ-NEINRFQCLCPTGFSGNLC 522



 Score =  115 bits (277), Expect = 2e-24
 Identities = 86/270 (31%), Positives = 114/270 (42%), Gaps = 36/270 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + G  C+K  C       G Y    NG   C  GW G EC+     C       HG
Sbjct: 187  CDDYYYGFGCNK-FCRPRDDFFGHYACDQNGNKTCMEGWMGPECN--RAICRQGCSPKHG 243

Query: 952  HC-VNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL 1009
             C + G C C  G++G +C +   PHP C  HG C E   C+C+  W G  C   DKD  
Sbjct: 244  SCKLPGDCRCQYGWQGLYCDKC-IPHPGCV-HGICNEPWQCLCETNWGGQLC---DKDLN 298

Query: 1010 QC--LPDCSGHGTFD---VDTQTCSCHAKWSGEDC--SKEVC-SLECGPHGRC----VGE 1057
             C     C   GT      D   CSC   +SG +C  ++  C S  C   G C    +G 
Sbjct: 299  YCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGF 358

Query: 1058 SCSCAAGWSGEFCSVRLCDA---RCAEHGQCK---NG-TCLCVSGWNGRHCTLEG--C-P 1107
             C C+ GW+G  CS  + D     C+  G C+   NG  C+C   W G+ C L+   C  
Sbjct: 359  ECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            + C     C+ +    + C C  GW G +C
Sbjct: 419  KPCVNAKSCK-NLIASYYCDCLPGWMGQNC 447



 Score =  113 bits (273), Expect = 7e-24
 Identities = 85/291 (29%), Positives = 108/291 (37%), Gaps = 36/291 (12%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C CN G+ G  C    ++CE   C   G C++G    KC C  G++G +C     DC   
Sbjct: 615  CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN 674

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGT-FDV-DTQTCSCH 1031
             C   G C +      C CK GWKG  C + D    +    C+  GT +D  D   C C 
Sbjct: 675  PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA--TCNNGGTCYDEGDAFKCMCP 732

Query: 1032 AKWSGEDC----SKEVCSLECGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CA 1080
              W G  C    +       C   G CV  GES  C C  GW G  C+    D     C 
Sbjct: 733  GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCY 792

Query: 1081 EHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
              G C +G     C C  G+ G  C   +  C  S    G   VD    + C C  G  G
Sbjct: 793  NSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSG 852

Query: 1135 PDCTTLKEQICDDSRDNDKDGLV---DCEDPECCQSPACKSSQLCVSSPKP 1182
              C  +  + C        DG     DC   +C       S   C   P+P
Sbjct: 853  AKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWC--GPRP 901



 Score =  104 bits (250), Expect = 4e-21
 Identities = 81/278 (29%), Positives = 120/278 (43%), Gaps = 40/278 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS-QRGE-YINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C++++C   CS + G   + G+C+C  GW+G  C    D+C   P C
Sbjct: 216  GNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYC----DKCIPHPGC 271

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCI-----EGTCVCKKGWKG 998
              HG C    +C C   + G+ C  +++ C  H  C   G C      +  C C +G+ G
Sbjct: 272  -VHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG 330

Query: 999  ADCGTMDKDALQCLPD-CSGHGTFDVDTQ--TCSCHAKWSGEDCSKEV--CS-LECGPHG 1052
             +C   +     CL D C   G+    +    C C   W+G  CS  +  CS   C   G
Sbjct: 331  PNCEIAEH---ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387

Query: 1053 RCV----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC 1101
             C     G  C C   W+G+ C +    C+A+ C     CKN      C C+ GW G++C
Sbjct: 388  TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447

Query: 1102 --TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
               +  C   C     CR D    + C C  G+ G  C
Sbjct: 448  DININDCLGQCQNDASCR-DLVNGYRCICPPGYAGDHC 484



 Score =  104 bits (249), Expect = 6e-21
 Identities = 80/263 (30%), Positives = 107/263 (40%), Gaps = 38/263 (14%)

Query: 875  THN-CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGEY----INGEC 924
            TH  C NG  CS  G      C C  G+ G +C  +    L   C  RG      +  EC
Sbjct: 302  THQPCLNGGTCSNTGPDKY-QCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC 360

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPT 978
            +C+PGW G  CS   D+C   +C+  G C   VNG KC C   + GK C     +C    
Sbjct: 361  ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP 420

Query: 979  CSGHGFC----IEGTCVCKKGWKGADCGTMDKDAL-QCLPDCSGHGTFDVDTQTCSCHAK 1033
            C     C        C C  GW G +C     D L QC  D S      V+   C C   
Sbjct: 421  CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDL--VNGYRCICPPG 478

Query: 1034 WSGEDCSKEV---CSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHG 1083
            ++G+ C +++    S  C   G C  E     C C  G+SG  C + +  C+   C    
Sbjct: 479  YAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGA 538

Query: 1084 QCKNGT----CLCVSGWNGRHCT 1102
            QC N      C C   + G++C+
Sbjct: 539  QCYNRASDYFCKCPEDYEGKNCS 561



 Score =  101 bits (242), Expect = 4e-20
 Identities = 93/295 (31%), Positives = 116/295 (39%), Gaps = 48/295 (16%)

Query: 866  FVALVAEEMTHNCP-NGCSGKGECLMG----HCQCQPGFGG-------DDCSKSVCPVLC 913
            F      E  ++C  N C   G C+ G     C C  G+ G       +DCS++ C    
Sbjct: 621  FTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGG 680

Query: 914  SQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC 969
            + R    +  C C  GWKGK C  R  +C+   CN  G C +     KC C  G++G  C
Sbjct: 681  TCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTC 740

Query: 970  G---EIDC-PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLP-DCSGHGT 1020
                   C P+P C   G C+      TCVCK+GW+G  C     D   C P  C   GT
Sbjct: 741  NIARNSSCLPNP-CHNGGTCVVNGESFTCVCKEGWEGPICAQNTND---CSPHPCYNSGT 796

Query: 1021 -FDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFC- 1070
              D D    C C   ++G DC     E  S  C     CV    G  C C  G SG  C 
Sbjct: 797  CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856

Query: 1071 --SVRLC--DARCAEHGQCKNGTCLCVSGWNGR-HCTLEGC-PRSC---AGHGQC 1116
              S R C         G   +  C      NGR  C+   C PR C    GH +C
Sbjct: 857  EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSEC 911



 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 16/177 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH   D +    +C   W G +C++ +C   C P HG C +   C C  GW 
Sbjct: 200  CRPRDDFFGHYACDQNGNK-TCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQ 258

Query: 1067 GEFCSVRLCDARCAEHGQCKNG-TCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G +C   +    C  HG C     CLC + W G+ C  +    G  + C   G C     
Sbjct: 259  GLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGP 317

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDD---SRDNDKDGLV--DCEDPECCQSPACKSS 1173
             +++C C +G+ GP+C   +     D   +R + K+  +  +CE       P C ++
Sbjct: 318  DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTN 374


>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged 1
            protein.
          Length = 1218

 Score =  121 bits (292), Expect = 3e-26
 Identities = 101/333 (30%), Positives = 129/333 (38%), Gaps = 68/333 (20%)

Query: 870  VAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE--- 923
            + E  ++ C NG   + E     C C  GF G+ C   +  C P  C    +  N     
Sbjct: 488  IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDY 547

Query: 924  -CQCNPGWKGKECS-----LRHDECEVPD----------------------CNGHGHCVN 955
             C+C   ++GK CS      R   CEV D                      C  HG C +
Sbjct: 548  FCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607

Query: 956  ---GK--CSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTM 1004
               GK  C C +G+ G +C E   DC    C   G CI+G     C+C  GW+GA C T 
Sbjct: 608  QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN 667

Query: 1005 DKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGEDC---SKEVCSLECGPHGRCVGE-- 1057
              D  Q    C   GT    V+   C C   W G+ C     +     C   G C  E  
Sbjct: 668  INDCSQ--NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD 725

Query: 1058 --SCSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNG---TCLCVSGWNGRHC---TLE 1104
               C C  GW G  C++    +     C   G C  NG   TC+C  GW G  C   T +
Sbjct: 726  AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND 785

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              P  C   G C VD D  + C+C  G+ GPDC
Sbjct: 786  CSPHPCYNSGTC-VDGDNWYRCECAPGFAGPDC 817



 Score =  120 bits (290), Expect = 6e-26
 Identities = 89/293 (30%), Positives = 118/293 (40%), Gaps = 37/293 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GCS K G C L G C+CQ G+ G  C K +    C         +C C   W G+ C
Sbjct: 234  CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLC 293

Query: 936  SLRHDECEV-PDCNGHGHCVNG-----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
                + C     C   G C N      +CSC  GY G  C   E  C    C   G C E
Sbjct: 294  DKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKE 353

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS 1040
             +    C C  GW G  C T   D   C P +CS  GT    V+   C C  +W+G+ C 
Sbjct: 354  TSLGFECECSPGWTGPTCSTNIDD---CSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ 410

Query: 1041 KEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL--CDARCAEHGQCK---NG 1088
             +    E  P               C C  GW G+ C + +  C  +C     C+   NG
Sbjct: 411  LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG 470

Query: 1089 -TCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+C  G+ G HC   ++ C  + C   G C+ +   R++C C  G+ G  C
Sbjct: 471  YRCICPPGYAGDHCERDIDECASNPCLNGGHCQ-NEINRFQCLCPTGFSGNLC 522



 Score =  115 bits (277), Expect = 2e-24
 Identities = 86/270 (31%), Positives = 114/270 (42%), Gaps = 36/270 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + G  C+K  C       G Y    NG   C  GW G EC+     C       HG
Sbjct: 187  CDDYYYGFGCNK-FCRPRDDFFGHYACDQNGNKTCMEGWMGPECN--RAICRQGCSPKHG 243

Query: 952  HC-VNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL 1009
             C + G C C  G++G +C +   PHP C  HG C E   C+C+  W G  C   DKD  
Sbjct: 244  SCKLPGDCRCQYGWQGLYCDKC-IPHPGCV-HGICNEPWQCLCETNWGGQLC---DKDLN 298

Query: 1010 QC--LPDCSGHGTFD---VDTQTCSCHAKWSGEDC--SKEVC-SLECGPHGRC----VGE 1057
             C     C   GT      D   CSC   +SG +C  ++  C S  C   G C    +G 
Sbjct: 299  YCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGF 358

Query: 1058 SCSCAAGWSGEFCSVRLCDA---RCAEHGQCK---NG-TCLCVSGWNGRHCTLEG--C-P 1107
             C C+ GW+G  CS  + D     C+  G C+   NG  C+C   W G+ C L+   C  
Sbjct: 359  ECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            + C     C+ +    + C C  GW G +C
Sbjct: 419  KPCVNAKSCK-NLIASYYCDCLPGWMGQNC 447



 Score =  113 bits (273), Expect = 7e-24
 Identities = 85/291 (29%), Positives = 108/291 (37%), Gaps = 36/291 (12%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C CN G+ G  C    ++CE   C   G C++G    KC C  G++G +C     DC   
Sbjct: 615  CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN 674

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGT-FDV-DTQTCSCH 1031
             C   G C +      C CK GWKG  C + D    +    C+  GT +D  D   C C 
Sbjct: 675  PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA--TCNNGGTCYDEGDAFKCMCP 732

Query: 1032 AKWSGEDC----SKEVCSLECGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CA 1080
              W G  C    +       C   G CV  GES  C C  GW G  C+    D     C 
Sbjct: 733  GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCY 792

Query: 1081 EHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
              G C +G     C C  G+ G  C   +  C  S    G   VD    + C C  G  G
Sbjct: 793  NSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSG 852

Query: 1135 PDCTTLKEQICDDSRDNDKDGLV---DCEDPECCQSPACKSSQLCVSSPKP 1182
              C  +  + C        DG     DC   +C       S   C   P+P
Sbjct: 853  AKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWC--GPRP 901



 Score =  104 bits (250), Expect = 4e-21
 Identities = 81/278 (29%), Positives = 120/278 (43%), Gaps = 40/278 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS-QRGE-YINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C++++C   CS + G   + G+C+C  GW+G  C    D+C   P C
Sbjct: 216  GNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYC----DKCIPHPGC 271

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCI-----EGTCVCKKGWKG 998
              HG C    +C C   + G+ C  +++ C  H  C   G C      +  C C +G+ G
Sbjct: 272  -VHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG 330

Query: 999  ADCGTMDKDALQCLPD-CSGHGTFDVDTQ--TCSCHAKWSGEDCSKEV--CS-LECGPHG 1052
             +C   +     CL D C   G+    +    C C   W+G  CS  +  CS   C   G
Sbjct: 331  PNCEIAEH---ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387

Query: 1053 RCV----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC 1101
             C     G  C C   W+G+ C +    C+A+ C     CKN      C C+ GW G++C
Sbjct: 388  TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447

Query: 1102 --TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
               +  C   C     CR D    + C C  G+ G  C
Sbjct: 448  DININDCLGQCQNDASCR-DLVNGYRCICPPGYAGDHC 484



 Score =  104 bits (249), Expect = 6e-21
 Identities = 80/263 (30%), Positives = 107/263 (40%), Gaps = 38/263 (14%)

Query: 875  THN-CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGEY----INGEC 924
            TH  C NG  CS  G      C C  G+ G +C  +    L   C  RG      +  EC
Sbjct: 302  THQPCLNGGTCSNTGPDKY-QCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC 360

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPT 978
            +C+PGW G  CS   D+C   +C+  G C   VNG KC C   + GK C     +C    
Sbjct: 361  ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP 420

Query: 979  CSGHGFC----IEGTCVCKKGWKGADCGTMDKDAL-QCLPDCSGHGTFDVDTQTCSCHAK 1033
            C     C        C C  GW G +C     D L QC  D S      V+   C C   
Sbjct: 421  CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDL--VNGYRCICPPG 478

Query: 1034 WSGEDCSKEV---CSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHG 1083
            ++G+ C +++    S  C   G C  E     C C  G+SG  C + +  C+   C    
Sbjct: 479  YAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGA 538

Query: 1084 QCKNGT----CLCVSGWNGRHCT 1102
            QC N      C C   + G++C+
Sbjct: 539  QCYNRASDYFCKCPEDYEGKNCS 561



 Score =  101 bits (242), Expect = 4e-20
 Identities = 93/295 (31%), Positives = 116/295 (39%), Gaps = 48/295 (16%)

Query: 866  FVALVAEEMTHNCP-NGCSGKGECLMG----HCQCQPGFGG-------DDCSKSVCPVLC 913
            F      E  ++C  N C   G C+ G     C C  G+ G       +DCS++ C    
Sbjct: 621  FTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGG 680

Query: 914  SQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC 969
            + R    +  C C  GWKGK C  R  +C+   CN  G C +     KC C  G++G  C
Sbjct: 681  TCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTC 740

Query: 970  G---EIDC-PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLP-DCSGHGT 1020
                   C P+P C   G C+      TCVCK+GW+G  C     D   C P  C   GT
Sbjct: 741  NIARNSSCLPNP-CHNGGTCVVNGESFTCVCKEGWEGPICAQNTND---CSPHPCYNSGT 796

Query: 1021 -FDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFC- 1070
              D D    C C   ++G DC     E  S  C     CV    G  C C  G SG  C 
Sbjct: 797  CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856

Query: 1071 --SVRLC--DARCAEHGQCKNGTCLCVSGWNGR-HCTLEGC-PRSC---AGHGQC 1116
              S R C         G   +  C      NGR  C+   C PR C    GH +C
Sbjct: 857  EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSEC 911



 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 16/177 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH   D +    +C   W G +C++ +C   C P HG C +   C C  GW 
Sbjct: 200  CRPRDDFFGHYACDQNGNK-TCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQ 258

Query: 1067 GEFCSVRLCDARCAEHGQCKNG-TCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G +C   +    C  HG C     CLC + W G+ C  +    G  + C   G C     
Sbjct: 259  GLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGP 317

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDD---SRDNDKDGLV--DCEDPECCQSPACKSS 1173
             +++C C +G+ GP+C   +     D   +R + K+  +  +CE       P C ++
Sbjct: 318  DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTN 374


>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille syndrome)
            protein.
          Length = 1218

 Score =  121 bits (292), Expect = 3e-26
 Identities = 101/333 (30%), Positives = 129/333 (38%), Gaps = 68/333 (20%)

Query: 870  VAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE--- 923
            + E  ++ C NG   + E     C C  GF G+ C   +  C P  C    +  N     
Sbjct: 488  IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDY 547

Query: 924  -CQCNPGWKGKECS-----LRHDECEVPD----------------------CNGHGHCVN 955
             C+C   ++GK CS      R   CEV D                      C  HG C +
Sbjct: 548  FCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607

Query: 956  ---GK--CSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTM 1004
               GK  C C +G+ G +C E   DC    C   G CI+G     C+C  GW+GA C T 
Sbjct: 608  QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN 667

Query: 1005 DKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGEDC---SKEVCSLECGPHGRCVGE-- 1057
              D  Q    C   GT    V+   C C   W G+ C     +     C   G C  E  
Sbjct: 668  INDCSQ--NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD 725

Query: 1058 --SCSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNG---TCLCVSGWNGRHC---TLE 1104
               C C  GW G  C++    +     C   G C  NG   TC+C  GW G  C   T +
Sbjct: 726  AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND 785

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              P  C   G C VD D  + C+C  G+ GPDC
Sbjct: 786  CSPHPCYNSGTC-VDGDNWYRCECAPGFAGPDC 817



 Score =  120 bits (290), Expect = 6e-26
 Identities = 89/293 (30%), Positives = 118/293 (40%), Gaps = 37/293 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GCS K G C L G C+CQ G+ G  C K +    C         +C C   W G+ C
Sbjct: 234  CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLC 293

Query: 936  SLRHDECEV-PDCNGHGHCVNG-----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
                + C     C   G C N      +CSC  GY G  C   E  C    C   G C E
Sbjct: 294  DKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKE 353

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS 1040
             +    C C  GW G  C T   D   C P +CS  GT    V+   C C  +W+G+ C 
Sbjct: 354  TSLGFECECSPGWTGPTCSTNIDD---CSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ 410

Query: 1041 KEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL--CDARCAEHGQCK---NG 1088
             +    E  P               C C  GW G+ C + +  C  +C     C+   NG
Sbjct: 411  LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG 470

Query: 1089 -TCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+C  G+ G HC   ++ C  + C   G C+ +   R++C C  G+ G  C
Sbjct: 471  YRCICPPGYAGDHCERDIDECASNPCLNGGHCQ-NEINRFQCLCPTGFSGNLC 522



 Score =  115 bits (277), Expect = 2e-24
 Identities = 86/270 (31%), Positives = 114/270 (42%), Gaps = 36/270 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + G  C+K  C       G Y    NG   C  GW G EC+     C       HG
Sbjct: 187  CDDYYYGFGCNK-FCRPRDDFFGHYACDQNGNKTCMEGWMGPECN--RAICRQGCSPKHG 243

Query: 952  HC-VNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL 1009
             C + G C C  G++G +C +   PHP C  HG C E   C+C+  W G  C   DKD  
Sbjct: 244  SCKLPGDCRCQYGWQGLYCDKC-IPHPGCV-HGICNEPWQCLCETNWGGQLC---DKDLN 298

Query: 1010 QC--LPDCSGHGTFD---VDTQTCSCHAKWSGEDC--SKEVC-SLECGPHGRC----VGE 1057
             C     C   GT      D   CSC   +SG +C  ++  C S  C   G C    +G 
Sbjct: 299  YCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGF 358

Query: 1058 SCSCAAGWSGEFCSVRLCDA---RCAEHGQCK---NG-TCLCVSGWNGRHCTLEG--C-P 1107
             C C+ GW+G  CS  + D     C+  G C+   NG  C+C   W G+ C L+   C  
Sbjct: 359  ECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            + C     C+ +    + C C  GW G +C
Sbjct: 419  KPCVNAKSCK-NLIASYYCDCLPGWMGQNC 447



 Score =  113 bits (273), Expect = 7e-24
 Identities = 85/291 (29%), Positives = 108/291 (37%), Gaps = 36/291 (12%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C CN G+ G  C    ++CE   C   G C++G    KC C  G++G +C     DC   
Sbjct: 615  CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN 674

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGT-FDV-DTQTCSCH 1031
             C   G C +      C CK GWKG  C + D    +    C+  GT +D  D   C C 
Sbjct: 675  PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA--TCNNGGTCYDEGDAFKCMCP 732

Query: 1032 AKWSGEDC----SKEVCSLECGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CA 1080
              W G  C    +       C   G CV  GES  C C  GW G  C+    D     C 
Sbjct: 733  GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCY 792

Query: 1081 EHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
              G C +G     C C  G+ G  C   +  C  S    G   VD    + C C  G  G
Sbjct: 793  NSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSG 852

Query: 1135 PDCTTLKEQICDDSRDNDKDGLV---DCEDPECCQSPACKSSQLCVSSPKP 1182
              C  +  + C        DG     DC   +C       S   C   P+P
Sbjct: 853  AKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWC--GPRP 901



 Score =  104 bits (250), Expect = 4e-21
 Identities = 81/278 (29%), Positives = 120/278 (43%), Gaps = 40/278 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS-QRGE-YINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C++++C   CS + G   + G+C+C  GW+G  C    D+C   P C
Sbjct: 216  GNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYC----DKCIPHPGC 271

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCI-----EGTCVCKKGWKG 998
              HG C    +C C   + G+ C  +++ C  H  C   G C      +  C C +G+ G
Sbjct: 272  -VHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG 330

Query: 999  ADCGTMDKDALQCLPD-CSGHGTFDVDTQ--TCSCHAKWSGEDCSKEV--CS-LECGPHG 1052
             +C   +     CL D C   G+    +    C C   W+G  CS  +  CS   C   G
Sbjct: 331  PNCEIAEH---ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387

Query: 1053 RCV----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC 1101
             C     G  C C   W+G+ C +    C+A+ C     CKN      C C+ GW G++C
Sbjct: 388  TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447

Query: 1102 --TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
               +  C   C     CR D    + C C  G+ G  C
Sbjct: 448  DININDCLGQCQNDASCR-DLVNGYRCICPPGYAGDHC 484



 Score =  104 bits (249), Expect = 6e-21
 Identities = 80/263 (30%), Positives = 107/263 (40%), Gaps = 38/263 (14%)

Query: 875  THN-CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGEY----INGEC 924
            TH  C NG  CS  G      C C  G+ G +C  +    L   C  RG      +  EC
Sbjct: 302  THQPCLNGGTCSNTGPDKY-QCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC 360

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPT 978
            +C+PGW G  CS   D+C   +C+  G C   VNG KC C   + GK C     +C    
Sbjct: 361  ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP 420

Query: 979  CSGHGFC----IEGTCVCKKGWKGADCGTMDKDAL-QCLPDCSGHGTFDVDTQTCSCHAK 1033
            C     C        C C  GW G +C     D L QC  D S      V+   C C   
Sbjct: 421  CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDL--VNGYRCICPPG 478

Query: 1034 WSGEDCSKEV---CSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHG 1083
            ++G+ C +++    S  C   G C  E     C C  G+SG  C + +  C+   C    
Sbjct: 479  YAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGA 538

Query: 1084 QCKNGT----CLCVSGWNGRHCT 1102
            QC N      C C   + G++C+
Sbjct: 539  QCYNRASDYFCKCPEDYEGKNCS 561



 Score =  101 bits (242), Expect = 4e-20
 Identities = 93/295 (31%), Positives = 116/295 (39%), Gaps = 48/295 (16%)

Query: 866  FVALVAEEMTHNCP-NGCSGKGECLMG----HCQCQPGFGG-------DDCSKSVCPVLC 913
            F      E  ++C  N C   G C+ G     C C  G+ G       +DCS++ C    
Sbjct: 621  FTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGG 680

Query: 914  SQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC 969
            + R    +  C C  GWKGK C  R  +C+   CN  G C +     KC C  G++G  C
Sbjct: 681  TCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTC 740

Query: 970  G---EIDC-PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLP-DCSGHGT 1020
                   C P+P C   G C+      TCVCK+GW+G  C     D   C P  C   GT
Sbjct: 741  NIARNSSCLPNP-CHNGGTCVVNGESFTCVCKEGWEGPICAQNTND---CSPHPCYNSGT 796

Query: 1021 -FDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFC- 1070
              D D    C C   ++G DC     E  S  C     CV    G  C C  G SG  C 
Sbjct: 797  CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856

Query: 1071 --SVRLC--DARCAEHGQCKNGTCLCVSGWNGR-HCTLEGC-PRSC---AGHGQC 1116
              S R C         G   +  C      NGR  C+   C PR C    GH +C
Sbjct: 857  EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSEC 911



 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 16/177 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH   D +    +C   W G +C++ +C   C P HG C +   C C  GW 
Sbjct: 200  CRPRDDFFGHYACDQNGNK-TCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQ 258

Query: 1067 GEFCSVRLCDARCAEHGQCKNG-TCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G +C   +    C  HG C     CLC + W G+ C  +    G  + C   G C     
Sbjct: 259  GLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGP 317

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDD---SRDNDKDGLV--DCEDPECCQSPACKSS 1173
             +++C C +G+ GP+C   +     D   +R + K+  +  +CE       P C ++
Sbjct: 318  DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTN 374


>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille syndrome)
            protein.
          Length = 1218

 Score =  121 bits (292), Expect = 3e-26
 Identities = 101/333 (30%), Positives = 129/333 (38%), Gaps = 68/333 (20%)

Query: 870  VAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE--- 923
            + E  ++ C NG   + E     C C  GF G+ C   +  C P  C    +  N     
Sbjct: 488  IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDY 547

Query: 924  -CQCNPGWKGKECS-----LRHDECEVPD----------------------CNGHGHCVN 955
             C+C   ++GK CS      R   CEV D                      C  HG C +
Sbjct: 548  FCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607

Query: 956  ---GK--CSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTM 1004
               GK  C C +G+ G +C E   DC    C   G CI+G     C+C  GW+GA C T 
Sbjct: 608  QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN 667

Query: 1005 DKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGEDC---SKEVCSLECGPHGRCVGE-- 1057
              D  Q    C   GT    V+   C C   W G+ C     +     C   G C  E  
Sbjct: 668  INDCSQ--NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD 725

Query: 1058 --SCSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNG---TCLCVSGWNGRHC---TLE 1104
               C C  GW G  C++    +     C   G C  NG   TC+C  GW G  C   T +
Sbjct: 726  AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND 785

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              P  C   G C VD D  + C+C  G+ GPDC
Sbjct: 786  CSPHPCYNSGTC-VDGDNWYRCECAPGFAGPDC 817



 Score =  120 bits (290), Expect = 6e-26
 Identities = 89/293 (30%), Positives = 118/293 (40%), Gaps = 37/293 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GCS K G C L G C+CQ G+ G  C K +    C         +C C   W G+ C
Sbjct: 234  CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLC 293

Query: 936  SLRHDECEV-PDCNGHGHCVNG-----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
                + C     C   G C N      +CSC  GY G  C   E  C    C   G C E
Sbjct: 294  DKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKE 353

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS 1040
             +    C C  GW G  C T   D   C P +CS  GT    V+   C C  +W+G+ C 
Sbjct: 354  TSLGFECECSPGWTGPTCSTNIDD---CSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ 410

Query: 1041 KEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL--CDARCAEHGQCK---NG 1088
             +    E  P               C C  GW G+ C + +  C  +C     C+   NG
Sbjct: 411  LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG 470

Query: 1089 -TCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+C  G+ G HC   ++ C  + C   G C+ +   R++C C  G+ G  C
Sbjct: 471  YRCICPPGYAGDHCERDIDECASNPCLNGGHCQ-NEINRFQCLCPTGFSGNLC 522



 Score =  115 bits (277), Expect = 2e-24
 Identities = 86/270 (31%), Positives = 114/270 (42%), Gaps = 36/270 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + G  C+K  C       G Y    NG   C  GW G EC+     C       HG
Sbjct: 187  CDDYYYGFGCNK-FCRPRDDFFGHYACDQNGNKTCMEGWMGPECN--RAICRQGCSPKHG 243

Query: 952  HC-VNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL 1009
             C + G C C  G++G +C +   PHP C  HG C E   C+C+  W G  C   DKD  
Sbjct: 244  SCKLPGDCRCQYGWQGLYCDKC-IPHPGCV-HGICNEPWQCLCETNWGGQLC---DKDLN 298

Query: 1010 QC--LPDCSGHGTFD---VDTQTCSCHAKWSGEDC--SKEVC-SLECGPHGRC----VGE 1057
             C     C   GT      D   CSC   +SG +C  ++  C S  C   G C    +G 
Sbjct: 299  YCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGF 358

Query: 1058 SCSCAAGWSGEFCSVRLCDA---RCAEHGQCK---NG-TCLCVSGWNGRHCTLEG--C-P 1107
             C C+ GW+G  CS  + D     C+  G C+   NG  C+C   W G+ C L+   C  
Sbjct: 359  ECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            + C     C+ +    + C C  GW G +C
Sbjct: 419  KPCVNAKSCK-NLIASYYCDCLPGWMGQNC 447



 Score =  113 bits (273), Expect = 7e-24
 Identities = 85/291 (29%), Positives = 108/291 (37%), Gaps = 36/291 (12%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C CN G+ G  C    ++CE   C   G C++G    KC C  G++G +C     DC   
Sbjct: 615  CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN 674

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGT-FDV-DTQTCSCH 1031
             C   G C +      C CK GWKG  C + D    +    C+  GT +D  D   C C 
Sbjct: 675  PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA--TCNNGGTCYDEGDAFKCMCP 732

Query: 1032 AKWSGEDC----SKEVCSLECGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CA 1080
              W G  C    +       C   G CV  GES  C C  GW G  C+    D     C 
Sbjct: 733  GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCY 792

Query: 1081 EHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
              G C +G     C C  G+ G  C   +  C  S    G   VD    + C C  G  G
Sbjct: 793  NSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSG 852

Query: 1135 PDCTTLKEQICDDSRDNDKDGLV---DCEDPECCQSPACKSSQLCVSSPKP 1182
              C  +  + C        DG     DC   +C       S   C   P+P
Sbjct: 853  AKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWC--GPRP 901



 Score =  104 bits (250), Expect = 4e-21
 Identities = 81/278 (29%), Positives = 120/278 (43%), Gaps = 40/278 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS-QRGE-YINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C++++C   CS + G   + G+C+C  GW+G  C    D+C   P C
Sbjct: 216  GNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYC----DKCIPHPGC 271

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCI-----EGTCVCKKGWKG 998
              HG C    +C C   + G+ C  +++ C  H  C   G C      +  C C +G+ G
Sbjct: 272  -VHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG 330

Query: 999  ADCGTMDKDALQCLPD-CSGHGTFDVDTQ--TCSCHAKWSGEDCSKEV--CS-LECGPHG 1052
             +C   +     CL D C   G+    +    C C   W+G  CS  +  CS   C   G
Sbjct: 331  PNCEIAEH---ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387

Query: 1053 RCV----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC 1101
             C     G  C C   W+G+ C +    C+A+ C     CKN      C C+ GW G++C
Sbjct: 388  TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447

Query: 1102 --TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
               +  C   C     CR D    + C C  G+ G  C
Sbjct: 448  DININDCLGQCQNDASCR-DLVNGYRCICPPGYAGDHC 484



 Score =  104 bits (249), Expect = 6e-21
 Identities = 80/263 (30%), Positives = 107/263 (40%), Gaps = 38/263 (14%)

Query: 875  THN-CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGEY----INGEC 924
            TH  C NG  CS  G      C C  G+ G +C  +    L   C  RG      +  EC
Sbjct: 302  THQPCLNGGTCSNTGPDKY-QCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC 360

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPT 978
            +C+PGW G  CS   D+C   +C+  G C   VNG KC C   + GK C     +C    
Sbjct: 361  ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP 420

Query: 979  CSGHGFC----IEGTCVCKKGWKGADCGTMDKDAL-QCLPDCSGHGTFDVDTQTCSCHAK 1033
            C     C        C C  GW G +C     D L QC  D S      V+   C C   
Sbjct: 421  CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDL--VNGYRCICPPG 478

Query: 1034 WSGEDCSKEV---CSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHG 1083
            ++G+ C +++    S  C   G C  E     C C  G+SG  C + +  C+   C    
Sbjct: 479  YAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGA 538

Query: 1084 QCKNGT----CLCVSGWNGRHCT 1102
            QC N      C C   + G++C+
Sbjct: 539  QCYNRASDYFCKCPEDYEGKNCS 561



 Score =  101 bits (242), Expect = 4e-20
 Identities = 93/295 (31%), Positives = 116/295 (39%), Gaps = 48/295 (16%)

Query: 866  FVALVAEEMTHNCP-NGCSGKGECLMG----HCQCQPGFGG-------DDCSKSVCPVLC 913
            F      E  ++C  N C   G C+ G     C C  G+ G       +DCS++ C    
Sbjct: 621  FTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGG 680

Query: 914  SQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC 969
            + R    +  C C  GWKGK C  R  +C+   CN  G C +     KC C  G++G  C
Sbjct: 681  TCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTC 740

Query: 970  G---EIDC-PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLP-DCSGHGT 1020
                   C P+P C   G C+      TCVCK+GW+G  C     D   C P  C   GT
Sbjct: 741  NIARNSSCLPNP-CHNGGTCVVNGESFTCVCKEGWEGPICAQNTND---CSPHPCYNSGT 796

Query: 1021 -FDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFC- 1070
              D D    C C   ++G DC     E  S  C     CV    G  C C  G SG  C 
Sbjct: 797  CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856

Query: 1071 --SVRLC--DARCAEHGQCKNGTCLCVSGWNGR-HCTLEGC-PRSC---AGHGQC 1116
              S R C         G   +  C      NGR  C+   C PR C    GH +C
Sbjct: 857  EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSEC 911



 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 16/177 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH   D +    +C   W G +C++ +C   C P HG C +   C C  GW 
Sbjct: 200  CRPRDDFFGHYACDQNGNK-TCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQ 258

Query: 1067 GEFCSVRLCDARCAEHGQCKNG-TCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G +C   +    C  HG C     CLC + W G+ C  +    G  + C   G C     
Sbjct: 259  GLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGP 317

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDD---SRDNDKDGLV--DCEDPECCQSPACKSS 1173
             +++C C +G+ GP+C   +     D   +R + K+  +  +CE       P C ++
Sbjct: 318  DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTN 374


>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille syndrome)
            protein.
          Length = 1218

 Score =  121 bits (292), Expect = 3e-26
 Identities = 101/333 (30%), Positives = 129/333 (38%), Gaps = 68/333 (20%)

Query: 870  VAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE--- 923
            + E  ++ C NG   + E     C C  GF G+ C   +  C P  C    +  N     
Sbjct: 488  IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDY 547

Query: 924  -CQCNPGWKGKECS-----LRHDECEVPD----------------------CNGHGHCVN 955
             C+C   ++GK CS      R   CEV D                      C  HG C +
Sbjct: 548  FCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607

Query: 956  ---GK--CSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTM 1004
               GK  C C +G+ G +C E   DC    C   G CI+G     C+C  GW+GA C T 
Sbjct: 608  QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN 667

Query: 1005 DKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGEDC---SKEVCSLECGPHGRCVGE-- 1057
              D  Q    C   GT    V+   C C   W G+ C     +     C   G C  E  
Sbjct: 668  INDCSQ--NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD 725

Query: 1058 --SCSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNG---TCLCVSGWNGRHC---TLE 1104
               C C  GW G  C++    +     C   G C  NG   TC+C  GW G  C   T +
Sbjct: 726  AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND 785

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              P  C   G C VD D  + C+C  G+ GPDC
Sbjct: 786  CSPHPCYNSGTC-VDGDNWYRCECAPGFAGPDC 817



 Score =  120 bits (290), Expect = 6e-26
 Identities = 89/293 (30%), Positives = 118/293 (40%), Gaps = 37/293 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GCS K G C L G C+CQ G+ G  C K +    C         +C C   W G+ C
Sbjct: 234  CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLC 293

Query: 936  SLRHDECEV-PDCNGHGHCVNG-----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
                + C     C   G C N      +CSC  GY G  C   E  C    C   G C E
Sbjct: 294  DKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKE 353

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS 1040
             +    C C  GW G  C T   D   C P +CS  GT    V+   C C  +W+G+ C 
Sbjct: 354  TSLGFECECSPGWTGPTCSTNIDD---CSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ 410

Query: 1041 KEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL--CDARCAEHGQCK---NG 1088
             +    E  P               C C  GW G+ C + +  C  +C     C+   NG
Sbjct: 411  LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG 470

Query: 1089 -TCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+C  G+ G HC   ++ C  + C   G C+ +   R++C C  G+ G  C
Sbjct: 471  YRCICPPGYAGDHCERDIDECASNPCLNGGHCQ-NEINRFQCLCPTGFSGNLC 522



 Score =  115 bits (277), Expect = 2e-24
 Identities = 86/270 (31%), Positives = 114/270 (42%), Gaps = 36/270 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + G  C+K  C       G Y    NG   C  GW G EC+     C       HG
Sbjct: 187  CDDYYYGFGCNK-FCRPRDDFFGHYACDQNGNKTCMEGWMGPECN--RAICRQGCSPKHG 243

Query: 952  HC-VNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL 1009
             C + G C C  G++G +C +   PHP C  HG C E   C+C+  W G  C   DKD  
Sbjct: 244  SCKLPGDCRCQYGWQGLYCDKC-IPHPGCV-HGICNEPWQCLCETNWGGQLC---DKDLN 298

Query: 1010 QC--LPDCSGHGTFD---VDTQTCSCHAKWSGEDC--SKEVC-SLECGPHGRC----VGE 1057
             C     C   GT      D   CSC   +SG +C  ++  C S  C   G C    +G 
Sbjct: 299  YCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGF 358

Query: 1058 SCSCAAGWSGEFCSVRLCDA---RCAEHGQCK---NG-TCLCVSGWNGRHCTLEG--C-P 1107
             C C+ GW+G  CS  + D     C+  G C+   NG  C+C   W G+ C L+   C  
Sbjct: 359  ECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            + C     C+ +    + C C  GW G +C
Sbjct: 419  KPCVNAKSCK-NLIASYYCDCLPGWMGQNC 447



 Score =  115 bits (276), Expect = 3e-24
 Identities = 85/291 (29%), Positives = 109/291 (37%), Gaps = 36/291 (12%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C CN G+ G  C    ++CE   C   G C++G    KC C  G++G +C     DC   
Sbjct: 615  CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN 674

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGT-FDV-DTQTCSCH 1031
             C   G C +      C CK GWKG  C + D    +    C+  GT +D  D   C C 
Sbjct: 675  PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA--TCNNGGTCYDEGDAFKCMCP 732

Query: 1032 AKWSGEDC----SKEVCSLECGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CA 1080
              W G  C    +       C   G CV  GES  C C  GW G  C+    D     C 
Sbjct: 733  GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCY 792

Query: 1081 EHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
              G C +G     C C  G+ G  C   +  C  S    G   VD    + C C  G  G
Sbjct: 793  NSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSG 852

Query: 1135 PDCTTLKEQICDDSRDNDKDGLV---DCEDPECCQSPACKSSQLCVSSPKP 1182
              C  +  + C       +DG     DC   +C       S   C   P+P
Sbjct: 853  AKCQEVSGRPCITMGSVIRDGAKWDDDCNTCQCLNGRIACSKVWC--GPRP 901



 Score =  104 bits (250), Expect = 4e-21
 Identities = 81/278 (29%), Positives = 120/278 (43%), Gaps = 40/278 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS-QRGE-YINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C++++C   CS + G   + G+C+C  GW+G  C    D+C   P C
Sbjct: 216  GNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYC----DKCIPHPGC 271

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCI-----EGTCVCKKGWKG 998
              HG C    +C C   + G+ C  +++ C  H  C   G C      +  C C +G+ G
Sbjct: 272  -VHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG 330

Query: 999  ADCGTMDKDALQCLPD-CSGHGTFDVDTQ--TCSCHAKWSGEDCSKEV--CS-LECGPHG 1052
             +C   +     CL D C   G+    +    C C   W+G  CS  +  CS   C   G
Sbjct: 331  PNCEIAEH---ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387

Query: 1053 RCV----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC 1101
             C     G  C C   W+G+ C +    C+A+ C     CKN      C C+ GW G++C
Sbjct: 388  TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447

Query: 1102 --TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
               +  C   C     CR D    + C C  G+ G  C
Sbjct: 448  DININDCLGQCQNDASCR-DLVNGYRCICPPGYAGDHC 484



 Score =  104 bits (249), Expect = 6e-21
 Identities = 80/263 (30%), Positives = 107/263 (40%), Gaps = 38/263 (14%)

Query: 875  THN-CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGEY----INGEC 924
            TH  C NG  CS  G      C C  G+ G +C  +    L   C  RG      +  EC
Sbjct: 302  THQPCLNGGTCSNTGPDKY-QCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC 360

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPT 978
            +C+PGW G  CS   D+C   +C+  G C   VNG KC C   + GK C     +C    
Sbjct: 361  ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP 420

Query: 979  CSGHGFC----IEGTCVCKKGWKGADCGTMDKDAL-QCLPDCSGHGTFDVDTQTCSCHAK 1033
            C     C        C C  GW G +C     D L QC  D S      V+   C C   
Sbjct: 421  CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDL--VNGYRCICPPG 478

Query: 1034 WSGEDCSKEV---CSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHG 1083
            ++G+ C +++    S  C   G C  E     C C  G+SG  C + +  C+   C    
Sbjct: 479  YAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGA 538

Query: 1084 QCKNGT----CLCVSGWNGRHCT 1102
            QC N      C C   + G++C+
Sbjct: 539  QCYNRASDYFCKCPEDYEGKNCS 561



 Score =  102 bits (244), Expect = 2e-20
 Identities = 94/299 (31%), Positives = 120/299 (40%), Gaps = 56/299 (18%)

Query: 866  FVALVAEEMTHNCP-NGCSGKGECLMG----HCQCQPGFGG-------DDCSKSVCPVLC 913
            F      E  ++C  N C   G C+ G     C C  G+ G       +DCS++ C    
Sbjct: 621  FTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGG 680

Query: 914  SQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC 969
            + R    +  C C  GWKGK C  R  +C+   CN  G C +     KC C  G++G  C
Sbjct: 681  TCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTC 740

Query: 970  G---EIDC-PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLP-DCSGHGT 1020
                   C P+P C   G C+      TCVCK+GW+G  C     D   C P  C   GT
Sbjct: 741  NIARNSSCLPNP-CHNGGTCVVNGESFTCVCKEGWEGPICAQNTND---CSPHPCYNSGT 796

Query: 1021 -FDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFCS 1071
              D D    C C   ++G DC     E  S  C     CV    G  C C  G SG  C 
Sbjct: 797  CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856

Query: 1072 VRLCDARCAEHGQ-CKNG--------TCLCVSGWNGR-HCTLEGC-PRSC---AGHGQC 1116
              +    C   G   ++G        TC C+   NGR  C+   C PR C    GH +C
Sbjct: 857  -EVSGRPCITMGSVIRDGAKWDDDCNTCQCL---NGRIACSKVWCGPRPCLLHKGHSEC 911



 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 16/177 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH   D +    +C   W G +C++ +C   C P HG C +   C C  GW 
Sbjct: 200  CRPRDDFFGHYACDQNGNK-TCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQ 258

Query: 1067 GEFCSVRLCDARCAEHGQCKNG-TCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G +C   +    C  HG C     CLC + W G+ C  +    G  + C   G C     
Sbjct: 259  GLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGP 317

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDD---SRDNDKDGLV--DCEDPECCQSPACKSS 1173
             +++C C +G+ GP+C   +     D   +R + K+  +  +CE       P C ++
Sbjct: 318  DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTN 374


>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille syndrome)
            protein.
          Length = 1218

 Score =  121 bits (292), Expect = 3e-26
 Identities = 101/333 (30%), Positives = 129/333 (38%), Gaps = 68/333 (20%)

Query: 870  VAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE--- 923
            + E  ++ C NG   + E     C C  GF G+ C   +  C P  C    +  N     
Sbjct: 488  IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDY 547

Query: 924  -CQCNPGWKGKECS-----LRHDECEVPD----------------------CNGHGHCVN 955
             C+C   ++GK CS      R   CEV D                      C  HG C +
Sbjct: 548  FCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607

Query: 956  ---GK--CSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTM 1004
               GK  C C +G+ G +C E   DC    C   G CI+G     C+C  GW+GA C T 
Sbjct: 608  QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN 667

Query: 1005 DKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGEDC---SKEVCSLECGPHGRCVGE-- 1057
              D  Q    C   GT    V+   C C   W G+ C     +     C   G C  E  
Sbjct: 668  INDCSQ--NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD 725

Query: 1058 --SCSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNG---TCLCVSGWNGRHC---TLE 1104
               C C  GW G  C++    +     C   G C  NG   TC+C  GW G  C   T +
Sbjct: 726  AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND 785

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              P  C   G C VD D  + C+C  G+ GPDC
Sbjct: 786  CSPHPCYNSGTC-VDGDNWYRCECAPGFAGPDC 817



 Score =  120 bits (290), Expect = 6e-26
 Identities = 89/293 (30%), Positives = 118/293 (40%), Gaps = 37/293 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GCS K G C L G C+CQ G+ G  C K +    C         +C C   W G+ C
Sbjct: 234  CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLC 293

Query: 936  SLRHDECEV-PDCNGHGHCVNG-----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
                + C     C   G C N      +CSC  GY G  C   E  C    C   G C E
Sbjct: 294  DKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKE 353

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS 1040
             +    C C  GW G  C T   D   C P +CS  GT    V+   C C  +W+G+ C 
Sbjct: 354  TSLGFECECSPGWTGPTCSTNIDD---CSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ 410

Query: 1041 KEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL--CDARCAEHGQCK---NG 1088
             +    E  P               C C  GW G+ C + +  C  +C     C+   NG
Sbjct: 411  LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG 470

Query: 1089 -TCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+C  G+ G HC   ++ C  + C   G C+ +   R++C C  G+ G  C
Sbjct: 471  YRCICPPGYAGDHCERDIDECASNPCLNGGHCQ-NEINRFQCLCPTGFSGNLC 522



 Score =  115 bits (277), Expect = 2e-24
 Identities = 86/270 (31%), Positives = 114/270 (42%), Gaps = 36/270 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + G  C+K  C       G Y    NG   C  GW G EC+     C       HG
Sbjct: 187  CDDYYYGFGCNK-FCRPRDDFFGHYACDQNGNKTCMEGWMGPECN--RAICRQGCSPKHG 243

Query: 952  HC-VNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL 1009
             C + G C C  G++G +C +   PHP C  HG C E   C+C+  W G  C   DKD  
Sbjct: 244  SCKLPGDCRCQYGWQGLYCDKC-IPHPGCV-HGICNEPWQCLCETNWGGQLC---DKDLN 298

Query: 1010 QC--LPDCSGHGTFD---VDTQTCSCHAKWSGEDC--SKEVC-SLECGPHGRC----VGE 1057
             C     C   GT      D   CSC   +SG +C  ++  C S  C   G C    +G 
Sbjct: 299  YCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGF 358

Query: 1058 SCSCAAGWSGEFCSVRLCDA---RCAEHGQCK---NG-TCLCVSGWNGRHCTLEG--C-P 1107
             C C+ GW+G  CS  + D     C+  G C+   NG  C+C   W G+ C L+   C  
Sbjct: 359  ECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            + C     C+ +    + C C  GW G +C
Sbjct: 419  KPCVNAKSCK-NLIASYYCDCLPGWMGQNC 447



 Score =  113 bits (273), Expect = 7e-24
 Identities = 85/291 (29%), Positives = 108/291 (37%), Gaps = 36/291 (12%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C CN G+ G  C    ++CE   C   G C++G    KC C  G++G +C     DC   
Sbjct: 615  CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN 674

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGT-FDV-DTQTCSCH 1031
             C   G C +      C CK GWKG  C + D    +    C+  GT +D  D   C C 
Sbjct: 675  PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA--TCNNGGTCYDEGDAFKCMCP 732

Query: 1032 AKWSGEDC----SKEVCSLECGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CA 1080
              W G  C    +       C   G CV  GES  C C  GW G  C+    D     C 
Sbjct: 733  GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCY 792

Query: 1081 EHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
              G C +G     C C  G+ G  C   +  C  S    G   VD    + C C  G  G
Sbjct: 793  NSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSG 852

Query: 1135 PDCTTLKEQICDDSRDNDKDGLV---DCEDPECCQSPACKSSQLCVSSPKP 1182
              C  +  + C        DG     DC   +C       S   C   P+P
Sbjct: 853  AKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWC--GPRP 901



 Score =  104 bits (250), Expect = 4e-21
 Identities = 81/278 (29%), Positives = 120/278 (43%), Gaps = 40/278 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS-QRGE-YINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C++++C   CS + G   + G+C+C  GW+G  C    D+C   P C
Sbjct: 216  GNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYC----DKCIPHPGC 271

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCI-----EGTCVCKKGWKG 998
              HG C    +C C   + G+ C  +++ C  H  C   G C      +  C C +G+ G
Sbjct: 272  -VHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG 330

Query: 999  ADCGTMDKDALQCLPD-CSGHGTFDVDTQ--TCSCHAKWSGEDCSKEV--CS-LECGPHG 1052
             +C   +     CL D C   G+    +    C C   W+G  CS  +  CS   C   G
Sbjct: 331  PNCEIAEH---ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387

Query: 1053 RCV----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC 1101
             C     G  C C   W+G+ C +    C+A+ C     CKN      C C+ GW G++C
Sbjct: 388  TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447

Query: 1102 --TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
               +  C   C     CR D    + C C  G+ G  C
Sbjct: 448  DININDCLGQCQNDASCR-DLVNGYRCICPPGYAGDHC 484



 Score =  104 bits (249), Expect = 6e-21
 Identities = 80/263 (30%), Positives = 107/263 (40%), Gaps = 38/263 (14%)

Query: 875  THN-CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGEY----INGEC 924
            TH  C NG  CS  G      C C  G+ G +C  +    L   C  RG      +  EC
Sbjct: 302  THQPCLNGGTCSNTGPDKY-QCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC 360

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPT 978
            +C+PGW G  CS   D+C   +C+  G C   VNG KC C   + GK C     +C    
Sbjct: 361  ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP 420

Query: 979  CSGHGFC----IEGTCVCKKGWKGADCGTMDKDAL-QCLPDCSGHGTFDVDTQTCSCHAK 1033
            C     C        C C  GW G +C     D L QC  D S      V+   C C   
Sbjct: 421  CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDL--VNGYRCICPPG 478

Query: 1034 WSGEDCSKEV---CSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHG 1083
            ++G+ C +++    S  C   G C  E     C C  G+SG  C + +  C+   C    
Sbjct: 479  YAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGA 538

Query: 1084 QCKNGT----CLCVSGWNGRHCT 1102
            QC N      C C   + G++C+
Sbjct: 539  QCYNRASDYFCKCPEDYEGKNCS 561



 Score =  101 bits (242), Expect = 4e-20
 Identities = 93/295 (31%), Positives = 116/295 (39%), Gaps = 48/295 (16%)

Query: 866  FVALVAEEMTHNCP-NGCSGKGECLMG----HCQCQPGFGG-------DDCSKSVCPVLC 913
            F      E  ++C  N C   G C+ G     C C  G+ G       +DCS++ C    
Sbjct: 621  FTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGG 680

Query: 914  SQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC 969
            + R    +  C C  GWKGK C  R  +C+   CN  G C +     KC C  G++G  C
Sbjct: 681  TCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTC 740

Query: 970  G---EIDC-PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLP-DCSGHGT 1020
                   C P+P C   G C+      TCVCK+GW+G  C     D   C P  C   GT
Sbjct: 741  NIARNSSCLPNP-CHNGGTCVVNGESFTCVCKEGWEGPICAQNTND---CSPHPCYNSGT 796

Query: 1021 -FDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFC- 1070
              D D    C C   ++G DC     E  S  C     CV    G  C C  G SG  C 
Sbjct: 797  CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856

Query: 1071 --SVRLC--DARCAEHGQCKNGTCLCVSGWNGR-HCTLEGC-PRSC---AGHGQC 1116
              S R C         G   +  C      NGR  C+   C PR C    GH +C
Sbjct: 857  EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSEC 911



 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 16/177 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH   D +    +C   W G +C++ +C   C P HG C +   C C  GW 
Sbjct: 200  CRPRDDFFGHYACDQNGNK-TCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQ 258

Query: 1067 GEFCSVRLCDARCAEHGQCKNG-TCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G +C   +    C  HG C     CLC + W G+ C  +    G  + C   G C     
Sbjct: 259  GLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGP 317

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDD---SRDNDKDGLV--DCEDPECCQSPACKSS 1173
             +++C C +G+ GP+C   +     D   +R + K+  +  +CE       P C ++
Sbjct: 318  DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTN 374


>AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.
          Length = 1238

 Score =  121 bits (292), Expect = 3e-26
 Identities = 94/315 (29%), Positives = 132/315 (41%), Gaps = 37/315 (11%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS--QRGEYINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C ++VC   C+    G  + GEC+C+ GW+G+ C    DEC   P C
Sbjct: 227  GNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC----DECVPYPGC 282

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCIEG-----TCVCKKGWKG 998
              HG CV   +C+C   + G  C  +++ C  H  C+  G CI        C C  G+ G
Sbjct: 283  -VHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSG 341

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCS---KEVCSLECGPHGRC 1054
             +C   +  A    P  +G    +V +   C C + WSG  C+    E  S  C   G C
Sbjct: 342  RNCEKAE-HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTC 400

Query: 1055 V----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC-- 1101
            V    G  C C   W G  C +    C+ + C     CKN      C C+ GW G +C  
Sbjct: 401  VDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHI 460

Query: 1102 TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
             +  C   C   G C+ D    ++C C  G+ G  C  L+   C  S  +      D  D
Sbjct: 461  NVNDCRGQCQHGGTCK-DLVNGYQCVCPRGFGGRHC-ELERDECASSPCHSGGLCEDLAD 518

Query: 1162 PECCQSPACKSSQLC 1176
               C  P   S  LC
Sbjct: 519  GFHCHCPQGFSGPLC 533



 Score =  109 bits (263), Expect = 1e-22
 Identities = 89/304 (29%), Positives = 116/304 (38%), Gaps = 47/304 (15%)

Query: 878  CPNGCSGKG------ECLMGHCQCQPGFGGD---DCSKSVCPVLCSQRGEYI-----NGE 923
            CP+   GK        C  G C+   G G D       +    +C   G  +     N  
Sbjct: 562  CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C C+ G+ G  C    D+C    C   G C++     +C C  G++G+ C     DC   
Sbjct: 622  CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC-LPDCSGHGT-FDV-DTQTCSC 1030
             C   G C +      C C  GWKG  C + +    QC    CS  GT +D  DT  C+C
Sbjct: 682  PCHSRGRCYDLVNDFYCACDDGWKGKTCHSRE---FQCDAYTCSNGGTCYDSGDTFRCAC 738

Query: 1031 HAKWSGEDC--SKEVCSL--ECGPHGRCVGE----SCSCAAGWSGEFCSVRLCDAR---C 1079
               W G  C  +K    L   C   G CVG     SC C  GW G  C+    D     C
Sbjct: 739  PPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPC 798

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
               G C +G     C C  G+ G  C   ++ C  S   +G   VD    + C C  G  
Sbjct: 799  YNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRA 858

Query: 1134 GPDC 1137
            GP C
Sbjct: 859  GPRC 862



 Score =  107 bits (257), Expect = 6e-22
 Identities = 98/330 (29%), Positives = 127/330 (38%), Gaps = 72/330 (21%)

Query: 876  HNCPNGCSGKGEC---LMGH-CQCQPGFGG-------DDCSKSVCPV--LCSQRGEYING 922
            ++C   C   G C   + G+ C C  GFGG       D+C+ S C    LC    +  + 
Sbjct: 463  NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFH- 521

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCG--EIDCPH 976
             C C  G+ G  C +  D CE   C     C N +    C+C   + GK C      CP 
Sbjct: 522  -CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPG 580

Query: 977  PTC-------------------SG----HGFCIEG-----TCVCKKGWKGADCGTMDKDA 1008
              C                   SG    HG C+       +C+C  G+ G  C     D 
Sbjct: 581  GACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDC 640

Query: 1009 LQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGPHGRC---VGES-C 1059
            L     C   GT   +VD   C C + W GE C      C  + C   GRC   V +  C
Sbjct: 641  LG--QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYC 698

Query: 1060 SCAAGWSGEFCSVR--LCDA-RCAEHGQCKNG----TCLCVSGWNGRHCTL---EGC-PR 1108
            +C  GW G+ C  R   CDA  C+  G C +      C C  GW G  C +     C P 
Sbjct: 699  ACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPN 758

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             C   G C V +   + C C DGW+G  CT
Sbjct: 759  PCVNGGTC-VGSGASFSCICRDGWEGRTCT 787



 Score =  101 bits (242), Expect = 4e-20
 Identities = 90/326 (27%), Positives = 124/326 (38%), Gaps = 60/326 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRG---EYING-ECQCNPGWK 931
            C N  S K      +C C PG+ G +C  +V  C   C   G   + +NG +C C  G+ 
Sbjct: 432  CLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFG 491

Query: 932  GKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGEID---CPHPTCSGHGF 984
            G+ C L  DEC    C+  G C    +G  C C +G+ G  C E+D   C    C     
Sbjct: 492  GRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLC-EVDVDLCEPSPCRNGAR 550

Query: 985  C--IEGT--CVCKKGWKGADCGT---------------MDKDALQCLPD------CSGHG 1019
            C  +EG   C C   + G +C                    DA   +P       C  HG
Sbjct: 551  CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHG 610

Query: 1020 ---TFDVDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVGE----SCSCAAGWSGEF 1069
               +      +C C + ++G  C + +  C    C   G C+ E     C C +GW GE 
Sbjct: 611  RCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGEL 670

Query: 1070 CSVRLCDAR---CAEHGQC----KNGTCLCVSGWNGRHCTLEG--CPR-SCAGHGQCRVD 1119
            C     D     C   G+C     +  C C  GW G+ C      C   +C+  G C  D
Sbjct: 671  CDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTC-YD 729

Query: 1120 NDGRWECKCFDGWDGPDCTTLKEQIC 1145
            +   + C C  GW G  C   K   C
Sbjct: 730  SGDTFRCACPPGWKGSTCAVAKNSSC 755



 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 104/367 (28%), Positives = 137/367 (37%), Gaps = 68/367 (18%)

Query: 876  HNCPNGCSG-KGECLMGHCQCQPGFGGDDCSKS--VCPVL-CSQRG---EYING-ECQCN 927
            H C NG +    E     C C  G+ G +C K+   C    C+  G   E  +G EC C 
Sbjct: 315  HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP 374

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSG 981
             GW G  C+L  DEC    C   G CV+     +C C   + G  C     +C    C  
Sbjct: 375  SGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLN 434

Query: 982  HGFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWS 1035
               C   I G  C C  GWKG +C     D   C   C   GT    V+   C C   + 
Sbjct: 435  AFSCKNLIGGYYCDCIPGWKGINCHINVND---CRGQCQHGGTCKDLVNGYQCVCPRGFG 491

Query: 1036 GEDCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFC--SVRLCD-ARCAEHGQC 1085
            G  C     E  S  C   G C     G  C C  G+SG  C   V LC+ + C    +C
Sbjct: 492  GRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARC 551

Query: 1086 KN--GT--CLCVSGWNGRHCTL--EGCPRS------------------------CAGHGQ 1115
             N  G   C C   + G++C++  E CP                          C  HG+
Sbjct: 552  YNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGR 611

Query: 1116 CRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG--LVDCEDPECCQSPACKSS 1173
            C     G + C C  G+ G  C    E I D      ++G   +D  D   C  P+    
Sbjct: 612  CVSQPGGNFSCICDSGFTGTYC---HENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEG 668

Query: 1174 QLCVSSP 1180
            +LC ++P
Sbjct: 669  ELCDTNP 675



 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 86/284 (30%), Positives = 118/284 (41%), Gaps = 49/284 (17%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRG---EYING-ECQCNPGW 930
            C NG +   E     C C  G+ G+ C  +   C P  C  RG   + +N   C C+ GW
Sbjct: 645  CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 704

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG---EIDC-PHPTCSGH 982
            KGK C  R  +C+   C+  G C +     +C+C  G+KG  C       C P+P C   
Sbjct: 705  KGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP-CVNG 763

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSGE 1037
            G C+      +C+C+ GW+G  C T + +    LP  +G    D V+   C C   ++G 
Sbjct: 764  GTCVGSGASFSCICRDGWEGRTC-THNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGP 822

Query: 1038 DCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFCSV-----RLCDARCA--EHG 1083
            DC     E  S  C     CV    G  CSC  G +G  C       R C +R     HG
Sbjct: 823  DCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHG 882

Query: 1084 -----QCKNGTCL-----CVSGWNG-RHCTLEGCPRSCAGHGQC 1116
                  C +  CL     C   W G + C L G P + +   QC
Sbjct: 883  SSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALS--AQC 924



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 52/185 (28%), Positives = 70/185 (37%), Gaps = 17/185 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH T D      +C   W G++C + VC   C   HG C V   C C+ GW 
Sbjct: 211  CRPRNDFFGHYTCD-QYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQ 269

Query: 1067 GEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G FC   +    C  HG C +   C C + W G  C  +    G    C   G C     
Sbjct: 270  GRFCDECVPYPGCV-HGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEP 328

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACK-SSQL 1175
             ++ C C DG+ G +C   +     +   N     +     +C  P     P C      
Sbjct: 329  DQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDE 388

Query: 1176 CVSSP 1180
            C S+P
Sbjct: 389  CASNP 393


>AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.
          Length = 1238

 Score =  121 bits (292), Expect = 3e-26
 Identities = 94/315 (29%), Positives = 132/315 (41%), Gaps = 37/315 (11%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS--QRGEYINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C ++VC   C+    G  + GEC+C+ GW+G+ C    DEC   P C
Sbjct: 227  GNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC----DECVPYPGC 282

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCIEG-----TCVCKKGWKG 998
              HG CV   +C+C   + G  C  +++ C  H  C+  G CI        C C  G+ G
Sbjct: 283  -VHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSG 341

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCS---KEVCSLECGPHGRC 1054
             +C   +  A    P  +G    +V +   C C + WSG  C+    E  S  C   G C
Sbjct: 342  RNCEKAE-HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTC 400

Query: 1055 V----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC-- 1101
            V    G  C C   W G  C +    C+ + C     CKN      C C+ GW G +C  
Sbjct: 401  VDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHI 460

Query: 1102 TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
             +  C   C   G C+ D    ++C C  G+ G  C  L+   C  S  +      D  D
Sbjct: 461  NVNDCRGQCQHGGTCK-DLVNGYQCVCPRGFGGRHC-ELERDKCASSPCHSGGLCEDLAD 518

Query: 1162 PECCQSPACKSSQLC 1176
               C  P   S  LC
Sbjct: 519  GFHCHCPQGFSGPLC 533



 Score =  109 bits (263), Expect = 1e-22
 Identities = 89/304 (29%), Positives = 116/304 (38%), Gaps = 47/304 (15%)

Query: 878  CPNGCSGKG------ECLMGHCQCQPGFGGD---DCSKSVCPVLCSQRGEYI-----NGE 923
            CP+   GK        C  G C+   G G D       +    +C   G  +     N  
Sbjct: 562  CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C C+ G+ G  C    D+C    C   G C++     +C C  G++G+ C     DC   
Sbjct: 622  CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC-LPDCSGHGT-FDV-DTQTCSC 1030
             C   G C +      C C  GWKG  C + +    QC    CS  GT +D  DT  C+C
Sbjct: 682  PCHSRGRCYDLVNDFYCACDDGWKGKTCHSRE---FQCDAYTCSNGGTCYDSGDTFRCAC 738

Query: 1031 HAKWSGEDC--SKEVCSL--ECGPHGRCVGE----SCSCAAGWSGEFCSVRLCDAR---C 1079
               W G  C  +K    L   C   G CVG     SC C  GW G  C+    D     C
Sbjct: 739  PPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPC 798

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
               G C +G     C C  G+ G  C   ++ C  S   +G   VD    + C C  G  
Sbjct: 799  YNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRA 858

Query: 1134 GPDC 1137
            GP C
Sbjct: 859  GPRC 862



 Score =  106 bits (254), Expect = 1e-21
 Identities = 98/330 (29%), Positives = 126/330 (38%), Gaps = 72/330 (21%)

Query: 876  HNCPNGCSGKGEC---LMGH-CQCQPGFGG-------DDCSKSVCPV--LCSQRGEYING 922
            ++C   C   G C   + G+ C C  GFGG       D C+ S C    LC    +  + 
Sbjct: 463  NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLADGFH- 521

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCG--EIDCPH 976
             C C  G+ G  C +  D CE   C     C N +    C+C   + GK C      CP 
Sbjct: 522  -CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPG 580

Query: 977  PTC-------------------SG----HGFCIEG-----TCVCKKGWKGADCGTMDKDA 1008
              C                   SG    HG C+       +C+C  G+ G  C     D 
Sbjct: 581  GACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDC 640

Query: 1009 LQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGPHGRC---VGES-C 1059
            L     C   GT   +VD   C C + W GE C      C  + C   GRC   V +  C
Sbjct: 641  LG--QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYC 698

Query: 1060 SCAAGWSGEFCSVR--LCDA-RCAEHGQCKNG----TCLCVSGWNGRHCTL---EGC-PR 1108
            +C  GW G+ C  R   CDA  C+  G C +      C C  GW G  C +     C P 
Sbjct: 699  ACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPN 758

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             C   G C V +   + C C DGW+G  CT
Sbjct: 759  PCVNGGTC-VGSGASFSCICRDGWEGRTCT 787



 Score =   99 bits (238), Expect = 1e-19
 Identities = 89/326 (27%), Positives = 124/326 (38%), Gaps = 60/326 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRG---EYING-ECQCNPGWK 931
            C N  S K      +C C PG+ G +C  +V  C   C   G   + +NG +C C  G+ 
Sbjct: 432  CLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFG 491

Query: 932  GKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGEID---CPHPTCSGHGF 984
            G+ C L  D+C    C+  G C    +G  C C +G+ G  C E+D   C    C     
Sbjct: 492  GRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLC-EVDVDLCEPSPCRNGAR 550

Query: 985  C--IEGT--CVCKKGWKGADCGT---------------MDKDALQCLPD------CSGHG 1019
            C  +EG   C C   + G +C                    DA   +P       C  HG
Sbjct: 551  CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHG 610

Query: 1020 ---TFDVDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVGE----SCSCAAGWSGEF 1069
               +      +C C + ++G  C + +  C    C   G C+ E     C C +GW GE 
Sbjct: 611  RCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGEL 670

Query: 1070 CSVRLCDAR---CAEHGQC----KNGTCLCVSGWNGRHCTLEG--CPR-SCAGHGQCRVD 1119
            C     D     C   G+C     +  C C  GW G+ C      C   +C+  G C  D
Sbjct: 671  CDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTC-YD 729

Query: 1120 NDGRWECKCFDGWDGPDCTTLKEQIC 1145
            +   + C C  GW G  C   K   C
Sbjct: 730  SGDTFRCACPPGWKGSTCAVAKNSSC 755



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 104/367 (28%), Positives = 137/367 (37%), Gaps = 68/367 (18%)

Query: 876  HNCPNGCSG-KGECLMGHCQCQPGFGGDDCSKS--VCPVL-CSQRG---EYING-ECQCN 927
            H C NG +    E     C C  G+ G +C K+   C    C+  G   E  +G EC C 
Sbjct: 315  HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP 374

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSG 981
             GW G  C+L  DEC    C   G CV+     +C C   + G  C     +C    C  
Sbjct: 375  SGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLN 434

Query: 982  HGFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWS 1035
               C   I G  C C  GWKG +C     D   C   C   GT    V+   C C   + 
Sbjct: 435  AFSCKNLIGGYYCDCIPGWKGINCHINVND---CRGQCQHGGTCKDLVNGYQCVCPRGFG 491

Query: 1036 GEDCSKE---VCSLECGPHGRCV----GESCSCAAGWSGEFC--SVRLCD-ARCAEHGQC 1085
            G  C  E     S  C   G C     G  C C  G+SG  C   V LC+ + C    +C
Sbjct: 492  GRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARC 551

Query: 1086 KN--GT--CLCVSGWNGRHCTL--EGCPRS------------------------CAGHGQ 1115
             N  G   C C   + G++C++  E CP                          C  HG+
Sbjct: 552  YNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGR 611

Query: 1116 CRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG--LVDCEDPECCQSPACKSS 1173
            C     G + C C  G+ G  C    E I D      ++G   +D  D   C  P+    
Sbjct: 612  CVSQPGGNFSCICDSGFTGTYC---HENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEG 668

Query: 1174 QLCVSSP 1180
            +LC ++P
Sbjct: 669  ELCDTNP 675



 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 86/284 (30%), Positives = 118/284 (41%), Gaps = 49/284 (17%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRG---EYING-ECQCNPGW 930
            C NG +   E     C C  G+ G+ C  +   C P  C  RG   + +N   C C+ GW
Sbjct: 645  CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 704

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG---EIDC-PHPTCSGH 982
            KGK C  R  +C+   C+  G C +     +C+C  G+KG  C       C P+P C   
Sbjct: 705  KGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP-CVNG 763

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSGE 1037
            G C+      +C+C+ GW+G  C T + +    LP  +G    D V+   C C   ++G 
Sbjct: 764  GTCVGSGASFSCICRDGWEGRTC-THNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGP 822

Query: 1038 DCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFCSV-----RLCDARCA--EHG 1083
            DC     E  S  C     CV    G  CSC  G +G  C       R C +R     HG
Sbjct: 823  DCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHG 882

Query: 1084 -----QCKNGTCL-----CVSGWNG-RHCTLEGCPRSCAGHGQC 1116
                  C +  CL     C   W G + C L G P + +   QC
Sbjct: 883  SSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALS--AQC 924



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 52/185 (28%), Positives = 70/185 (37%), Gaps = 17/185 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH T D      +C   W G++C + VC   C   HG C V   C C+ GW 
Sbjct: 211  CRPRNDFFGHYTCD-QYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQ 269

Query: 1067 GEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G FC   +    C  HG C +   C C + W G  C  +    G    C   G C     
Sbjct: 270  GRFCDECVPYPGCV-HGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEP 328

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACK-SSQL 1175
             ++ C C DG+ G +C   +     +   N     +     +C  P     P C      
Sbjct: 329  DQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDE 388

Query: 1176 CVSSP 1180
            C S+P
Sbjct: 389  CASNP 393


>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein Jagged
            1 protein.
          Length = 1218

 Score =  121 bits (292), Expect = 3e-26
 Identities = 101/333 (30%), Positives = 129/333 (38%), Gaps = 68/333 (20%)

Query: 870  VAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE--- 923
            + E  ++ C NG   + E     C C  GF G+ C   +  C P  C    +  N     
Sbjct: 488  IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDY 547

Query: 924  -CQCNPGWKGKECS-----LRHDECEVPD----------------------CNGHGHCVN 955
             C+C   ++GK CS      R   CEV D                      C  HG C +
Sbjct: 548  FCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607

Query: 956  ---GK--CSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTM 1004
               GK  C C +G+ G +C E   DC    C   G CI+G     C+C  GW+GA C T 
Sbjct: 608  QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN 667

Query: 1005 DKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGEDC---SKEVCSLECGPHGRCVGE-- 1057
              D  Q    C   GT    V+   C C   W G+ C     +     C   G C  E  
Sbjct: 668  INDCSQ--NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD 725

Query: 1058 --SCSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNG---TCLCVSGWNGRHC---TLE 1104
               C C  GW G  C++    +     C   G C  NG   TC+C  GW G  C   T +
Sbjct: 726  AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND 785

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              P  C   G C VD D  + C+C  G+ GPDC
Sbjct: 786  CSPHPCYNSGTC-VDGDNWYRCECAPGFAGPDC 817



 Score =  120 bits (290), Expect = 6e-26
 Identities = 89/293 (30%), Positives = 118/293 (40%), Gaps = 37/293 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GCS K G C L G C+CQ G+ G  C K +    C         +C C   W G+ C
Sbjct: 234  CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLC 293

Query: 936  SLRHDECEV-PDCNGHGHCVNG-----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
                + C     C   G C N      +CSC  GY G  C   E  C    C   G C E
Sbjct: 294  DKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKE 353

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS 1040
             +    C C  GW G  C T   D   C P +CS  GT    V+   C C  +W+G+ C 
Sbjct: 354  TSLGFECECSPGWTGPTCSTNIDD---CSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ 410

Query: 1041 KEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL--CDARCAEHGQCK---NG 1088
             +    E  P               C C  GW G+ C + +  C  +C     C+   NG
Sbjct: 411  LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG 470

Query: 1089 -TCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+C  G+ G HC   ++ C  + C   G C+ +   R++C C  G+ G  C
Sbjct: 471  YRCICPPGYAGDHCERDIDECASNPCLNGGHCQ-NEINRFQCLCPTGFSGNLC 522



 Score =  115 bits (277), Expect = 2e-24
 Identities = 86/270 (31%), Positives = 114/270 (42%), Gaps = 36/270 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + G  C+K  C       G Y    NG   C  GW G EC+     C       HG
Sbjct: 187  CDDYYYGFGCNK-FCRPRDDFFGHYACDQNGNKTCMEGWMGPECN--RAICRQGCSPKHG 243

Query: 952  HC-VNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL 1009
             C + G C C  G++G +C +   PHP C  HG C E   C+C+  W G  C   DKD  
Sbjct: 244  SCKLPGDCRCQYGWQGLYCDKC-IPHPGCV-HGICNEPWQCLCETNWGGQLC---DKDLN 298

Query: 1010 QC--LPDCSGHGTFD---VDTQTCSCHAKWSGEDC--SKEVC-SLECGPHGRC----VGE 1057
             C     C   GT      D   CSC   +SG +C  ++  C S  C   G C    +G 
Sbjct: 299  YCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGF 358

Query: 1058 SCSCAAGWSGEFCSVRLCDA---RCAEHGQCK---NG-TCLCVSGWNGRHCTLEG--C-P 1107
             C C+ GW+G  CS  + D     C+  G C+   NG  C+C   W G+ C L+   C  
Sbjct: 359  ECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            + C     C+ +    + C C  GW G +C
Sbjct: 419  KPCVNAKSCK-NLIASYYCDCLPGWMGQNC 447



 Score =  113 bits (273), Expect = 7e-24
 Identities = 85/291 (29%), Positives = 108/291 (37%), Gaps = 36/291 (12%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C CN G+ G  C    ++CE   C   G C++G    KC C  G++G +C     DC   
Sbjct: 615  CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN 674

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGT-FDV-DTQTCSCH 1031
             C   G C +      C CK GWKG  C + D    +    C+  GT +D  D   C C 
Sbjct: 675  PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA--TCNNGGTCYDEGDAFKCMCP 732

Query: 1032 AKWSGEDC----SKEVCSLECGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CA 1080
              W G  C    +       C   G CV  GES  C C  GW G  C+    D     C 
Sbjct: 733  GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCY 792

Query: 1081 EHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
              G C +G     C C  G+ G  C   +  C  S    G   VD    + C C  G  G
Sbjct: 793  NSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSG 852

Query: 1135 PDCTTLKEQICDDSRDNDKDGLV---DCEDPECCQSPACKSSQLCVSSPKP 1182
              C  +  + C        DG     DC   +C       S   C   P+P
Sbjct: 853  AKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWC--GPRP 901



 Score =  104 bits (250), Expect = 4e-21
 Identities = 81/278 (29%), Positives = 120/278 (43%), Gaps = 40/278 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS-QRGE-YINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C++++C   CS + G   + G+C+C  GW+G  C    D+C   P C
Sbjct: 216  GNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYC----DKCIPHPGC 271

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCI-----EGTCVCKKGWKG 998
              HG C    +C C   + G+ C  +++ C  H  C   G C      +  C C +G+ G
Sbjct: 272  -VHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG 330

Query: 999  ADCGTMDKDALQCLPD-CSGHGTFDVDTQ--TCSCHAKWSGEDCSKEV--CS-LECGPHG 1052
             +C   +     CL D C   G+    +    C C   W+G  CS  +  CS   C   G
Sbjct: 331  PNCEIAEH---ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387

Query: 1053 RCV----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC 1101
             C     G  C C   W+G+ C +    C+A+ C     CKN      C C+ GW G++C
Sbjct: 388  TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447

Query: 1102 --TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
               +  C   C     CR D    + C C  G+ G  C
Sbjct: 448  DININDCLGQCQNDASCR-DLVNGYRCICPPGYAGDHC 484



 Score =  104 bits (249), Expect = 6e-21
 Identities = 80/263 (30%), Positives = 107/263 (40%), Gaps = 38/263 (14%)

Query: 875  THN-CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGEY----INGEC 924
            TH  C NG  CS  G      C C  G+ G +C  +    L   C  RG      +  EC
Sbjct: 302  THQPCLNGGTCSNTGPDKY-QCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC 360

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPT 978
            +C+PGW G  CS   D+C   +C+  G C   VNG KC C   + GK C     +C    
Sbjct: 361  ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP 420

Query: 979  CSGHGFC----IEGTCVCKKGWKGADCGTMDKDAL-QCLPDCSGHGTFDVDTQTCSCHAK 1033
            C     C        C C  GW G +C     D L QC  D S      V+   C C   
Sbjct: 421  CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDL--VNGYRCICPPG 478

Query: 1034 WSGEDCSKEV---CSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHG 1083
            ++G+ C +++    S  C   G C  E     C C  G+SG  C + +  C+   C    
Sbjct: 479  YAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGA 538

Query: 1084 QCKNGT----CLCVSGWNGRHCT 1102
            QC N      C C   + G++C+
Sbjct: 539  QCYNRASDYFCKCPEDYEGKNCS 561



 Score =  101 bits (242), Expect = 4e-20
 Identities = 93/295 (31%), Positives = 116/295 (39%), Gaps = 48/295 (16%)

Query: 866  FVALVAEEMTHNCP-NGCSGKGECLMG----HCQCQPGFGG-------DDCSKSVCPVLC 913
            F      E  ++C  N C   G C+ G     C C  G+ G       +DCS++ C    
Sbjct: 621  FTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGG 680

Query: 914  SQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC 969
            + R    +  C C  GWKGK C  R  +C+   CN  G C +     KC C  G++G  C
Sbjct: 681  TCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTC 740

Query: 970  G---EIDC-PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLP-DCSGHGT 1020
                   C P+P C   G C+      TCVCK+GW+G  C     D   C P  C   GT
Sbjct: 741  NIARNSSCLPNP-CHNGGTCVVNGESFTCVCKEGWEGPICAQNTND---CSPHPCYNSGT 796

Query: 1021 -FDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFC- 1070
              D D    C C   ++G DC     E  S  C     CV    G  C C  G SG  C 
Sbjct: 797  CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856

Query: 1071 --SVRLC--DARCAEHGQCKNGTCLCVSGWNGR-HCTLEGC-PRSC---AGHGQC 1116
              S R C         G   +  C      NGR  C+   C PR C    GH +C
Sbjct: 857  EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSEC 911



 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 16/177 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH   D +    +C   W G +C++ +C   C P HG C +   C C  GW 
Sbjct: 200  CRPRDDFFGHYACDQNGNK-TCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQ 258

Query: 1067 GEFCSVRLCDARCAEHGQCKNG-TCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G +C   +    C  HG C     CLC + W G+ C  +    G  + C   G C     
Sbjct: 259  GLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGP 317

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDD---SRDNDKDGLV--DCEDPECCQSPACKSS 1173
             +++C C +G+ GP+C   +     D   +R + K+  +  +CE       P C ++
Sbjct: 318  DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTN 374


>AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.
          Length = 1238

 Score =  121 bits (292), Expect = 3e-26
 Identities = 94/315 (29%), Positives = 132/315 (41%), Gaps = 37/315 (11%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS--QRGEYINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C ++VC   C+    G  + GEC+C+ GW+G+ C    DEC   P C
Sbjct: 227  GNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC----DECVPYPGC 282

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCIEG-----TCVCKKGWKG 998
              HG CV   +C+C   + G  C  +++ C  H  C+  G CI        C C  G+ G
Sbjct: 283  -VHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSG 341

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCS---KEVCSLECGPHGRC 1054
             +C   +  A    P  +G    +V +   C C + WSG  C+    E  S  C   G C
Sbjct: 342  RNCEKAE-HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTC 400

Query: 1055 V----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC-- 1101
            V    G  C C   W G  C +    C+ + C     CKN      C C+ GW G +C  
Sbjct: 401  VDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHI 460

Query: 1102 TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
             +  C   C   G C+ D    ++C C  G+ G  C  L+   C  S  +      D  D
Sbjct: 461  NVNDCRGQCQHGGTCK-DLVNGYQCVCPRGFGGRHC-ELERDKCASSPCHSGGLCEDLAD 518

Query: 1162 PECCQSPACKSSQLC 1176
               C  P   S  LC
Sbjct: 519  GFHCHCPQGFSGPLC 533



 Score =  109 bits (263), Expect = 1e-22
 Identities = 89/304 (29%), Positives = 116/304 (38%), Gaps = 47/304 (15%)

Query: 878  CPNGCSGKG------ECLMGHCQCQPGFGGD---DCSKSVCPVLCSQRGEYI-----NGE 923
            CP+   GK        C  G C+   G G D       +    +C   G  +     N  
Sbjct: 562  CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C C+ G+ G  C    D+C    C   G C++     +C C  G++G+ C     DC   
Sbjct: 622  CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC-LPDCSGHGT-FDV-DTQTCSC 1030
             C   G C +      C C  GWKG  C + +    QC    CS  GT +D  DT  C+C
Sbjct: 682  PCHSRGRCYDLVNDFYCACDDGWKGKTCHSRE---FQCDAYTCSNGGTCYDSGDTFRCAC 738

Query: 1031 HAKWSGEDC--SKEVCSL--ECGPHGRCVGE----SCSCAAGWSGEFCSVRLCDAR---C 1079
               W G  C  +K    L   C   G CVG     SC C  GW G  C+    D     C
Sbjct: 739  PPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPC 798

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
               G C +G     C C  G+ G  C   ++ C  S   +G   VD    + C C  G  
Sbjct: 799  YNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRA 858

Query: 1134 GPDC 1137
            GP C
Sbjct: 859  GPRC 862



 Score =  106 bits (254), Expect = 1e-21
 Identities = 98/330 (29%), Positives = 126/330 (38%), Gaps = 72/330 (21%)

Query: 876  HNCPNGCSGKGEC---LMGH-CQCQPGFGG-------DDCSKSVCPV--LCSQRGEYING 922
            ++C   C   G C   + G+ C C  GFGG       D C+ S C    LC    +  + 
Sbjct: 463  NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCHSGGLCEDLADGFH- 521

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCG--EIDCPH 976
             C C  G+ G  C +  D CE   C     C N +    C+C   + GK C      CP 
Sbjct: 522  -CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPG 580

Query: 977  PTC-------------------SG----HGFCIEG-----TCVCKKGWKGADCGTMDKDA 1008
              C                   SG    HG C+       +C+C  G+ G  C     D 
Sbjct: 581  GACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDC 640

Query: 1009 LQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGPHGRC---VGES-C 1059
            L     C   GT   +VD   C C + W GE C      C  + C   GRC   V +  C
Sbjct: 641  LG--QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYC 698

Query: 1060 SCAAGWSGEFCSVR--LCDA-RCAEHGQCKNG----TCLCVSGWNGRHCTL---EGC-PR 1108
            +C  GW G+ C  R   CDA  C+  G C +      C C  GW G  C +     C P 
Sbjct: 699  ACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPN 758

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             C   G C V +   + C C DGW+G  CT
Sbjct: 759  PCVNGGTC-VGSGASFSCICRDGWEGRTCT 787



 Score =   99 bits (238), Expect = 1e-19
 Identities = 89/326 (27%), Positives = 124/326 (38%), Gaps = 60/326 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRG---EYING-ECQCNPGWK 931
            C N  S K      +C C PG+ G +C  +V  C   C   G   + +NG +C C  G+ 
Sbjct: 432  CLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFG 491

Query: 932  GKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGEID---CPHPTCSGHGF 984
            G+ C L  D+C    C+  G C    +G  C C +G+ G  C E+D   C    C     
Sbjct: 492  GRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLC-EVDVDLCEPSPCRNGAR 550

Query: 985  C--IEGT--CVCKKGWKGADCGT---------------MDKDALQCLPD------CSGHG 1019
            C  +EG   C C   + G +C                    DA   +P       C  HG
Sbjct: 551  CYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHG 610

Query: 1020 ---TFDVDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVGE----SCSCAAGWSGEF 1069
               +      +C C + ++G  C + +  C    C   G C+ E     C C +GW GE 
Sbjct: 611  RCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGEL 670

Query: 1070 CSVRLCDAR---CAEHGQC----KNGTCLCVSGWNGRHCTLEG--CPR-SCAGHGQCRVD 1119
            C     D     C   G+C     +  C C  GW G+ C      C   +C+  G C  D
Sbjct: 671  CDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTC-YD 729

Query: 1120 NDGRWECKCFDGWDGPDCTTLKEQIC 1145
            +   + C C  GW G  C   K   C
Sbjct: 730  SGDTFRCACPPGWKGSTCAVAKNSSC 755



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 104/367 (28%), Positives = 137/367 (37%), Gaps = 68/367 (18%)

Query: 876  HNCPNGCSG-KGECLMGHCQCQPGFGGDDCSKS--VCPVL-CSQRG---EYING-ECQCN 927
            H C NG +    E     C C  G+ G +C K+   C    C+  G   E  +G EC C 
Sbjct: 315  HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP 374

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSG 981
             GW G  C+L  DEC    C   G CV+     +C C   + G  C     +C    C  
Sbjct: 375  SGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLN 434

Query: 982  HGFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWS 1035
               C   I G  C C  GWKG +C     D   C   C   GT    V+   C C   + 
Sbjct: 435  AFSCKNLIGGYYCDCIPGWKGINCHINVND---CRGQCQHGGTCKDLVNGYQCVCPRGFG 491

Query: 1036 GEDCSKE---VCSLECGPHGRCV----GESCSCAAGWSGEFC--SVRLCD-ARCAEHGQC 1085
            G  C  E     S  C   G C     G  C C  G+SG  C   V LC+ + C    +C
Sbjct: 492  GRHCELERDKCASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARC 551

Query: 1086 KN--GT--CLCVSGWNGRHCTL--EGCPRS------------------------CAGHGQ 1115
             N  G   C C   + G++C++  E CP                          C  HG+
Sbjct: 552  YNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGR 611

Query: 1116 CRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG--LVDCEDPECCQSPACKSS 1173
            C     G + C C  G+ G  C    E I D      ++G   +D  D   C  P+    
Sbjct: 612  CVSQPGGNFSCICDSGFTGTYC---HENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEG 668

Query: 1174 QLCVSSP 1180
            +LC ++P
Sbjct: 669  ELCDTNP 675



 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 86/284 (30%), Positives = 118/284 (41%), Gaps = 49/284 (17%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRG---EYING-ECQCNPGW 930
            C NG +   E     C C  G+ G+ C  +   C P  C  RG   + +N   C C+ GW
Sbjct: 645  CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 704

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG---EIDC-PHPTCSGH 982
            KGK C  R  +C+   C+  G C +     +C+C  G+KG  C       C P+P C   
Sbjct: 705  KGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP-CVNG 763

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSGE 1037
            G C+      +C+C+ GW+G  C T + +    LP  +G    D V+   C C   ++G 
Sbjct: 764  GTCVGSGASFSCICRDGWEGRTC-THNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGP 822

Query: 1038 DCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFCSV-----RLCDARCA--EHG 1083
            DC     E  S  C     CV    G  CSC  G +G  C       R C +R     HG
Sbjct: 823  DCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHG 882

Query: 1084 -----QCKNGTCL-----CVSGWNG-RHCTLEGCPRSCAGHGQC 1116
                  C +  CL     C   W G + C L G P + +   QC
Sbjct: 883  SSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALS--AQC 924



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 52/185 (28%), Positives = 70/185 (37%), Gaps = 17/185 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH T D      +C   W G++C + VC   C   HG C V   C C+ GW 
Sbjct: 211  CRPRNDFFGHYTCD-QYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQ 269

Query: 1067 GEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G FC   +    C  HG C +   C C + W G  C  +    G    C   G C     
Sbjct: 270  GRFCDECVPYPGCV-HGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEP 328

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACK-SSQL 1175
             ++ C C DG+ G +C   +     +   N     +     +C  P     P C      
Sbjct: 329  DQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDE 388

Query: 1176 CVSSP 1180
            C S+P
Sbjct: 389  CASNP 393


>Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.
          Length = 1223

 Score =  121 bits (291), Expect = 5e-26
 Identities = 94/316 (29%), Positives = 132/316 (41%), Gaps = 38/316 (12%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS--QRGEYINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C ++VC   C+    G  + GEC+C+ GW+G+ C    DEC   P C
Sbjct: 211  GNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC----DECVPYPGC 266

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCIEG-----TCVCKKGWKG 998
              HG CV   +C+C   + G  C  +++ C  H  C+  G CI        C C  G+ G
Sbjct: 267  -VHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSG 325

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCSK----EVCSLECGPHGR 1053
             +C   +  A    P  +G    +V +   C C + WSG  C+     E  S  C   G 
Sbjct: 326  RNCEKAE-HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCASADIDECASNPCAAGGT 384

Query: 1054 CV----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC- 1101
            CV    G  C C   W G  C +    C+ + C     CKN      C C+ GW G +C 
Sbjct: 385  CVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCH 444

Query: 1102 -TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCE 1160
              +  C   C   G C+ D    ++C C  G+ G  C  L+   C  S  +      D  
Sbjct: 445  INVNDCRGQCQHGGTCK-DLVNGYQCVCPRGFGGRHC-ELERDECASSPCHSGGLCEDLA 502

Query: 1161 DPECCQSPACKSSQLC 1176
            D   C  P   S  LC
Sbjct: 503  DGFHCHCPQGFSGPLC 518



 Score =  118 bits (284), Expect = 3e-25
 Identities = 98/298 (32%), Positives = 123/298 (41%), Gaps = 54/298 (18%)

Query: 879  PNGCSGKGEC--LMG--HCQCQPGFGGDDCS--KSVCPVLCSQRGEYING-ECQCNPGWK 931
            P+ C     C  L G  +C C   FGG +CS  +  CP         I+G      PG  
Sbjct: 527  PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCP---GGACRVIDGCGSDAGPGMP 583

Query: 932  GKECSLRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGKFCGEI--DCPHPTCSGHGF 984
            G   S          C  HG CV     N  C C  G+ G +C E   DC    C   G 
Sbjct: 584  GTAAS--------GVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 635

Query: 985  CIEGT----CVCKKGWKGADCGTMDKDALQCLPD-CSGHGT-FD-VDTQTCSCHAKWSGE 1037
            CI+      C C  GW+G  C T   D   CLPD C   G  +D V+   C+C   W G+
Sbjct: 636  CIDEVDAFRCFCPSGWEGELCDTNPND---CLPDPCHSRGRCYDLVNDFYCACDDGWKGK 692

Query: 1038 DC-SKEV-C-SLECGPHGRCV--GES--CSCAAGWSGEFCSVRLCDA----RCAEHGQCK 1086
             C S+E  C +  C   G C   G++  C+C  GW G  C+V    +     C   G C 
Sbjct: 693  TCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCV 752

Query: 1087 NG----TCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                  +C+C  GW GR CT     C P  C   G C VD    + C+C  G+ GPDC
Sbjct: 753  GSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGIC-VDGVNWFRCECAPGFAGPDC 809



 Score =  117 bits (282), Expect = 6e-25
 Identities = 100/334 (29%), Positives = 133/334 (39%), Gaps = 48/334 (14%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRG---EYING-ECQCNPGWK 931
            C N  S K      +C C PG+ G +C  +V  C   C   G   + +NG +C C  G+ 
Sbjct: 417  CLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFG 476

Query: 932  GKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGEID---CPHPTCSGHGF 984
            G+ C L  DEC    C+  G C    +G  C C +G+ G  C E+D   C    C     
Sbjct: 477  GRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLC-EVDVDLCEPSPCRNGAR 535

Query: 985  C--IEGT--CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS 1040
            C  +EG   C C   + G +C    +        C G     +D   C   A   G    
Sbjct: 536  CYNLEGDYYCACPDDFGGKNCSVPRE-------PCPGGACRVID--GCGSDA---GPGMP 583

Query: 1041 KEVCSLECGPHGRCVGE-----SCSCAAGWSGEFCSVRLCDA---RCAEHGQCKNGT--- 1089
                S  CGPHGRCV +     SC C +G++G +C   + D     C   G C +     
Sbjct: 584  GTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAF 643

Query: 1090 -CLCVSGWNGRHCTL--EGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQIC 1145
             C C SGW G  C      C P  C   G+C  D    + C C DGW G  C + +E  C
Sbjct: 644  RCFCPSGWEGELCDTNPNDCLPDPCHSRGRC-YDLVNDFYCACDDGWKGKTCHS-REFQC 701

Query: 1146 DDSRDNDKDGLVDCEDP-ECCQSPACKSSQLCVS 1178
            D    ++     D  D   C   P  K S   V+
Sbjct: 702  DAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVA 735



 Score =  109 bits (263), Expect = 1e-22
 Identities = 89/304 (29%), Positives = 116/304 (38%), Gaps = 47/304 (15%)

Query: 878  CPNGCSGKG------ECLMGHCQCQPGFGGD---DCSKSVCPVLCSQRGEYI-----NGE 923
            CP+   GK        C  G C+   G G D       +    +C   G  +     N  
Sbjct: 547  CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 606

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C C+ G+ G  C    D+C    C   G C++     +C C  G++G+ C     DC   
Sbjct: 607  CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 666

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC-LPDCSGHGT-FDV-DTQTCSC 1030
             C   G C +      C C  GWKG  C + +    QC    CS  GT +D  DT  C+C
Sbjct: 667  PCHSRGRCYDLVNDFYCACDDGWKGKTCHSRE---FQCDAYTCSNGGTCYDSGDTFRCAC 723

Query: 1031 HAKWSGEDCS--KEVCSLE--CGPHGRCVGE----SCSCAAGWSGEFCSVRLCDAR---C 1079
               W G  C+  K    L   C   G CVG     SC C  GW G  C+    D     C
Sbjct: 724  PPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPC 783

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
               G C +G     C C  G+ G  C   ++ C  S   +G   VD    + C C  G  
Sbjct: 784  YNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRA 843

Query: 1134 GPDC 1137
            GP C
Sbjct: 844  GPRC 847



 Score =  107 bits (257), Expect = 6e-22
 Identities = 98/330 (29%), Positives = 127/330 (38%), Gaps = 72/330 (21%)

Query: 876  HNCPNGCSGKGEC---LMGH-CQCQPGFGG-------DDCSKSVCPV--LCSQRGEYING 922
            ++C   C   G C   + G+ C C  GFGG       D+C+ S C    LC    +  + 
Sbjct: 448  NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFH- 506

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCG--EIDCPH 976
             C C  G+ G  C +  D CE   C     C N +    C+C   + GK C      CP 
Sbjct: 507  -CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPG 565

Query: 977  PTC-------------------SG----HGFCIEG-----TCVCKKGWKGADCGTMDKDA 1008
              C                   SG    HG C+       +C+C  G+ G  C     D 
Sbjct: 566  GACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDC 625

Query: 1009 LQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--CSLE-CGPHGRC---VGES-C 1059
            L     C   GT   +VD   C C + W GE C      C  + C   GRC   V +  C
Sbjct: 626  LG--QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYC 683

Query: 1060 SCAAGWSGEFCSVR--LCDA-RCAEHGQCKNG----TCLCVSGWNGRHCTL---EGC-PR 1108
            +C  GW G+ C  R   CDA  C+  G C +      C C  GW G  C +     C P 
Sbjct: 684  ACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPN 743

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             C   G C V +   + C C DGW+G  CT
Sbjct: 744  PCVNGGTC-VGSGASFSCICRDGWEGRTCT 772



 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 86/284 (30%), Positives = 118/284 (41%), Gaps = 49/284 (17%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRG---EYING-ECQCNPGW 930
            C NG +   E     C C  G+ G+ C  +   C P  C  RG   + +N   C C+ GW
Sbjct: 630  CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 689

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG---EIDC-PHPTCSGH 982
            KGK C  R  +C+   C+  G C +     +C+C  G+KG  C       C P+P C   
Sbjct: 690  KGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP-CVNG 748

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSGE 1037
            G C+      +C+C+ GW+G  C T + +    LP  +G    D V+   C C   ++G 
Sbjct: 749  GTCVGSGASFSCICRDGWEGRTC-THNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGP 807

Query: 1038 DCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFCSV-----RLCDARCA--EHG 1083
            DC     E  S  C     CV    G  CSC  G +G  C       R C +R     HG
Sbjct: 808  DCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHG 867

Query: 1084 -----QCKNGTCL-----CVSGWNG-RHCTLEGCPRSCAGHGQC 1116
                  C +  CL     C   W G + C L G P + +   QC
Sbjct: 868  SSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALS--AQC 909



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 97/345 (28%), Positives = 135/345 (39%), Gaps = 49/345 (14%)

Query: 872  EEMTHNCP-NGCSGKGECL---MG-HCQCQPGFGGDDCSKSVCPVL----CSQRG---EY 919
            E+  H C  N C+  G C     G  C C  G+ G  C+ +         C+  G   + 
Sbjct: 329  EKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCASADIDECASNPCAAGGTCVDQ 388

Query: 920  ING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFC--GEI 972
            ++G EC C   W G  C L  +ECE   C     C N      C C+ G+KG  C     
Sbjct: 389  VDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVN 448

Query: 973  DCPHPTCSGHGFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDV-DTQT 1027
            DC    C   G C   + G  CVC +G+ G  C  +++D     P  SG    D+ D   
Sbjct: 449  DC-RGQCQHGGTCKDLVNGYQCVCPRGFGGRHC-ELERDECASSPCHSGGLCEDLADGFH 506

Query: 1028 CSCHAKWSGEDCSKEVCSLE---CGPHGRCV---GE-SCSCAAGWSGEFCSVRLCDARCA 1080
            C C   +SG  C  +V   E   C    RC    G+  C+C   + G+ CSV        
Sbjct: 507  CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSV-------- 558

Query: 1081 EHGQCKNGTCLCVSG-WNGRHCTLEGCPRS--CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C  G C  + G  +     + G   S  C  HG+C     G + C C  G+ G  C
Sbjct: 559  PREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC 618

Query: 1138 TTLKEQICDDSRDNDKDG--LVDCEDPECCQSPACKSSQLCVSSP 1180
                E I D      ++G   +D  D   C  P+    +LC ++P
Sbjct: 619  ---HENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNP 660



 Score = 77.8 bits (183), Expect = 6e-13
 Identities = 53/186 (28%), Positives = 73/186 (39%), Gaps = 18/186 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH T D      +C   W G++C + VC   C   HG C V   C C+ GW 
Sbjct: 195  CRPRNDFFGHYTCD-QYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQ 253

Query: 1067 GEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G FC   +    C  HG C +   C C + W G  C  +    G    C   G C     
Sbjct: 254  GRFCDECVPYPGCV-HGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEP 312

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACKSSQL- 1175
             ++ C C DG+ G +C   +     +   N     +     +C  P     P C S+ + 
Sbjct: 313  DQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCASADID 372

Query: 1176 -CVSSP 1180
             C S+P
Sbjct: 373  ECASNP 378


>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
          Length = 2321

 Score =  120 bits (290), Expect = 6e-26
 Identities = 91/284 (32%), Positives = 116/284 (40%), Gaps = 44/284 (15%)

Query: 893  CQCQPGFGG-------DDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKECSLRHDECEV 944
            C+C  G  G       DDC+ + C     + G  IN  +C C PG+ G  C++  +EC  
Sbjct: 606  CRCPSGTTGVNCEVNIDDCASNPCTFGVCRDG--INRYDCVCQPGFTGPLCNVEINECAS 663

Query: 945  PDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIEG----TCVCKK 994
              C   G CV+G    +C C  G     C      C H  CS HG C +      CVC+ 
Sbjct: 664  SPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCS-HGICYDAPGGFRCVCEP 722

Query: 995  GWKGADCG-TMDKDALQCLPDCSGHGTFDVDTQ--TCSCHAKWSGEDCS-KEVCSLE-CG 1049
            GW G  C  ++ +DA +  P C   GT   D     C+C     G  C     C+   C 
Sbjct: 723  GWSGPRCSQSLARDACESQP-CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCE 781

Query: 1050 PHGRCVGES-----CSCAAGWSGEFC--SVRLC--DARCAEHGQCKN----GTCLCVSGW 1096
              GRC         CSC  GW G  C   V  C   A C  HG C N     +C C  G+
Sbjct: 782  HGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY 841

Query: 1097 NGRHC--TLEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             G  C   +  C P  C   G C+ D  G + C C  G+ GP C
Sbjct: 842  TGPSCDQDINDCDPNPCLNGGSCQ-DGVGSFSCSCLPGFAGPRC 884



 Score =  116 bits (279), Expect = 1e-24
 Identities = 100/356 (28%), Positives = 136/356 (38%), Gaps = 52/356 (14%)

Query: 872  EEMTHNCPNG-CSGKGECL--MGH--CQCQPGFGG-------DDCSKSVCPV--LCSQRG 917
            E   + C +G C  +  CL  +G   C C  GF G       D+C  S C    +C  R 
Sbjct: 429  ETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDR- 487

Query: 918  EYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-E 971
              +NG  C C  G+ G  C L  DEC    C     CV+     +C C  G++G  C   
Sbjct: 488  --VNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRN 545

Query: 972  IDCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQ 1026
            +D   P    HG C++G    +C C  G+ G  C +   D  +  P   G    D VD  
Sbjct: 546  VDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCES-QVDECRSQPCRHGGKCLDLVDKY 604

Query: 1027 TCSCHAKWSGEDCSKEV--CSLECGPHGRCVG----ESCSCAAGWSGEFCSVRL---CDA 1077
             C C +  +G +C   +  C+      G C        C C  G++G  C+V +     +
Sbjct: 605  LCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASS 664

Query: 1078 RCAEHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDG 1131
             C E G C +G     CLC  G     C      C      HG C  D  G + C C  G
Sbjct: 665  PCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC-YDAPGGFRCVCEPG 723

Query: 1132 WDGPDCT------TLKEQICDDSRDNDKDGL-VDCEDPECCQSPACKSSQLCVSSP 1180
            W GP C+        + Q C        DG+   C  P   Q   C+    C  +P
Sbjct: 724  WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP 779



 Score =  113 bits (273), Expect = 7e-24
 Identities = 96/317 (30%), Positives = 129/317 (40%), Gaps = 58/317 (18%)

Query: 872  EEMTHNCPNGCSGKGECLMG--------HCQCQPGFGGDDCS------KSVCP--VLCS- 914
            E+  H+ P  C+G+G C            C+C  GF G DCS       S C     CS 
Sbjct: 79   EDPCHSGP--CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSV 136

Query: 915  -QRGEYINGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVNG----KCSCVRGYKGKF 968
               G ++   C C PG++G+ C    DEC V + C   G C+N     +C C  GY G  
Sbjct: 137  GPDGRFL---CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPL 193

Query: 969  CGE--IDCPHPTCSGHGFCIEG-----TCVCKKGWKGADC--GTMDKDALQCLPDCSGHG 1019
            C    + C    C   G C +       C C  G++G +C     D    +CL    G  
Sbjct: 194  CENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLN--GGTC 251

Query: 1020 TFDVDTQTCSCHAKWSGEDCSKEV--CSLE---CGPHGRCV----GESCSCAAGWSGEFC 1070
               V+T  C C  +W+G+ C+++V  C L+   C   G C     G SC C  GW+GE C
Sbjct: 252  VDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESC 311

Query: 1071 SVRLCD---ARCAEHGQCKNGT----CLCVSGWNGRHCTLEGCPRSCAGHGQCRVDN--- 1120
            S  + D   A C     C +      C C  G  G  C L+    S   H     D    
Sbjct: 312  SQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPV 371

Query: 1121 DGRWECKCFDGWDGPDC 1137
            +GR  C C  G+ G  C
Sbjct: 372  NGRAICTCPPGFTGGAC 388



 Score =  106 bits (255), Expect = 1e-21
 Identities = 89/290 (30%), Positives = 121/290 (41%), Gaps = 46/290 (15%)

Query: 893  CQCQPGFGGDDCSKSV--CPV--LCSQRGEYING----ECQCNPGWKGKECSLRHDECEV 944
            C C PG+ G  C   V  C V   C   G  +N      CQC  G+ G  C      C  
Sbjct: 144  CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAP 203

Query: 945  PDCNGHGHC-----VNGKCSCVRGYKGKFCGEI---DCPHPTCSGHGFCIEGT----CVC 992
              C   G C     +   C+C+ G++G+ C E+   DCP   C   G C++G     C C
Sbjct: 204  SPCRNGGTCRQSGDLTYDCACLPGFEGQNC-EVNVDDCPGHRCLNGGTCVDGVNTYNCQC 262

Query: 993  KKGWKGADCGTMDKDALQCLPD-CSGHGT-FD-VDTQTCSCHAKWSGEDCSKEV--CSLE 1047
               W G  C T D D  Q  P+ C   GT F+ +   +C C   W+GE CS+ +  C+  
Sbjct: 263  PPEWTGQFC-TEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATA 321

Query: 1048 CGPHG-----RCVGESCSCAAGWSGEFCSVR-LCDAR-CAEHGQCK----NGT--CLCVS 1094
               HG     R     C+C  G +G  C +   C +  C E   C     NG   C C  
Sbjct: 322  VCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPP 381

Query: 1095 GWNGRHCT--LEGCP---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            G+ G  C   ++ C      C   G+C V+  G + C+C  G+ GP C T
Sbjct: 382  GFTGGACDQDVDECSIGANPCEHLGRC-VNTQGSFLCQCGRGYTGPRCET 430



 Score =  103 bits (248), Expect = 7e-21
 Identities = 89/297 (29%), Positives = 113/297 (38%), Gaps = 42/297 (14%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYING----ECQCNPGWK 931
            C NG     +     C+C  GF G  C ++V  C       G  ++G     C C PG+ 
Sbjct: 516  CRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYT 575

Query: 932  GKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFCGEI---DCPHPTCSGHGF 984
            G  C  + DEC    C   G C++      C C  G  G  C E+   DC    C+  G 
Sbjct: 576  GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNC-EVNIDDCASNPCT-FGV 633

Query: 985  CIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CSCHAKWSGE 1037
            C +G     CVC+ G+ G  C     +  +C     G G   VD +    C C       
Sbjct: 634  CRDGINRYDCVCQPGFTGPLCNV---EINECASSPCGEGGSCVDGENGFRCLCPPGSLPP 690

Query: 1038 DC--SKEVCSLECGPHGRCV----GESCSCAAGWSGEFCSVRL----CDAR-CAEHGQCK 1086
             C      C+ E   HG C     G  C C  GWSG  CS  L    C+++ C   G C 
Sbjct: 691  LCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCS 750

Query: 1087 NG----TCLCVSGWNGRHC-TLEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            +      C C  G  GR C  L  C P  C   G+C         C C  GW GP C
Sbjct: 751  SDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRC 807



 Score =  103 bits (246), Expect = 1e-20
 Identities = 86/310 (27%), Positives = 119/310 (38%), Gaps = 46/310 (14%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG--------KCSCVRGYKGKFCGEID-C 974
            C C PGW G+ C L  D C    C G G C +          C C RG++G  C   D C
Sbjct: 65   CLCPPGWVGERCQL-EDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPC 123

Query: 975  PHPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ--- 1026
                C+    C  G      C C  G++G  C + D D  +    C  HG   ++T    
Sbjct: 124  LSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-DVDECRVGEPCR-HGGTCLNTPGSF 181

Query: 1027 TCSCHAKWSGEDCSKEV--CS-LECGPHGRC-----VGESCSCAAGWSGEFCSVRLCDA- 1077
             C C A ++G  C      C+   C   G C     +   C+C  G+ G+ C V + D  
Sbjct: 182  RCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCP 241

Query: 1078 --RCAEHGQCKNG----TCLCVSGWNGRHCT--LEGC---PRSCAGHGQCRVDNDGRWEC 1126
              RC   G C +G     C C   W G+ CT  ++ C   P +C   G C  +  G   C
Sbjct: 242  GHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTC-FNTLGGHSC 300

Query: 1127 KCFDGWDGPDCT----TLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSPK 1181
             C +GW G  C+         +C   +  +D+     C  P       C     CVS+P 
Sbjct: 301  VCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPC 360

Query: 1182 PTDILLRKQP 1191
              D +    P
Sbjct: 361  HEDAICDTNP 370



 Score = 97.5 bits (232), Expect = 6e-19
 Identities = 92/313 (29%), Positives = 116/313 (37%), Gaps = 49/313 (15%)

Query: 879  PNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVLCSQRG------EYINGECQCNP 928
            PN C   G C  G     C C PGF G  C++ V   L +  G         +  C C P
Sbjct: 855  PNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPP 914

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPHPTCSGH 982
            G+ G  C     +C    C   G CV+G     C C  GY G  C  E D C    C   
Sbjct: 915  GYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHG 974

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
            G C        C C + + G  C T+  D     P C   G        C C   WSG  
Sbjct: 975  GVCSAAHPGFRCTCLESFTGPQCQTL-VDWCSRQP-CQNGGRCVQTGAYCLCPPGWSGRL 1032

Query: 1039 CS------KEVCS-----LE--CGPHGRCVGES----CSCAAGWSGEFC--SVRLCDARC 1079
            C       +E  +     LE  C   G+CV E     C C  G +G  C   V  C A+ 
Sbjct: 1033 CDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQP 1092

Query: 1080 AEHGQCKNG-----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
             +HG    G      C C+ G+NG +C   ++ C      HG   +D   R+ C C  G 
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGT 1152

Query: 1133 DGPDCTTLKEQIC 1145
             G  C  + E  C
Sbjct: 1153 LGVLC-EINEDDC 1164



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 89/305 (29%), Positives = 125/305 (40%), Gaps = 53/305 (17%)

Query: 882  CSGKGECLM-----GHCQCQPGFGGDDCS-KSVC-PVLCSQRG----EYING----ECQC 926
            C+  G C         C C PG+ G+ C  +  C    C+ RG      + G     C+C
Sbjct: 49   CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108

Query: 927  NPGWKGKECSLRHDECEVPDCNGHGHCVNGK-----CSCVRGYKGKFC-GEID-C-PHPT 978
              G++G +CSL  D C    C     C  G      CSC  GY+G+ C  ++D C     
Sbjct: 109  PRGFRGPDCSL-PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 167

Query: 979  CSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVD---TQTCSC 1030
            C   G C+   G+  C C  G+ G  C   +  A+ C P  C   GT       T  C+C
Sbjct: 168  CRHGGTCLNTPGSFRCQCPAGYTGPLC---ENPAVPCAPSPCRNGGTCRQSGDLTYDCAC 224

Query: 1031 HAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR--- 1078
               + G++C   V  C    C   G CV      +C C   W+G+FC+  V  C  +   
Sbjct: 225  LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNA 284

Query: 1079 CAEHGQCKN----GTCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
            C   G C N     +C+CV+GW G  C+  ++ C  +   HG    D    + C C  G 
Sbjct: 285  CHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGK 344

Query: 1133 DGPDC 1137
             G  C
Sbjct: 345  TGLLC 349



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 88/303 (29%), Positives = 118/303 (38%), Gaps = 51/303 (16%)

Query: 882  CSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---------CSQRGEYINGECQCNP 928
            C   G CL       CQC  G+ G  C     P           C Q G+ +  +C C P
Sbjct: 168  CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGD-LTYDCACLP 226

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP-HP-TCS 980
            G++G+ C +  D+C    C   G CV+G     C C   + G+FC E +D C   P  C 
Sbjct: 227  GFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACH 286

Query: 981  GHGFCIE----GTCVCKKGWKGADCGTMDKDALQ--CLPDCSGHGTFDVDTQTCSCHAKW 1034
              G C       +CVC  GW G  C     D     C    + H    V +  C+C    
Sbjct: 287  NGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDR--VASFYCACPMGK 344

Query: 1035 SGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFC--SVRLCD--ARCAEH 1082
            +G  C   + C S  C     C      G + C+C  G++G  C   V  C   A   EH
Sbjct: 345  TGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEH 404

Query: 1083 -GQCKN--GT--CLCVSGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
             G+C N  G+  C C  G+ G  C     E     C     C +D  G++ C C  G+ G
Sbjct: 405  LGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATC-LDRIGQFTCICMAGFTG 463

Query: 1135 PDC 1137
              C
Sbjct: 464  TYC 466



 Score = 83.0 bits (196), Expect = 1e-14
 Identities = 102/361 (28%), Positives = 131/361 (36%), Gaps = 77/361 (21%)

Query: 882  CSGKGECL----MGHCQCQPGFGGDDCSKSVCPVL---CSQRGE---YINGE-CQCNPGW 930
            C   G+C+      +C C  G  G  C + V P L   C   G    Y+ G  C+C PG+
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY 1114

Query: 931  KGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFC--GEIDC-------PHP 977
             G  C    DEC    C   G C++      CSC  G  G  C   E DC         P
Sbjct: 1115 NGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1174

Query: 978  TCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDTQ-----T 1027
             C  +G C++      C C  G+ G  C   + D  +C    C    T D          
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGYTGLRC---EADINECRSGACHAAHTRDCLQDPGGGFR 1231

Query: 1028 CSCHAKWSGEDCSKEVCSLE---CGPHGRC---------VGESCSCAAGWSGEFCS--VR 1073
            C CHA +SG  C   +   E   C   G+C         +  +C CA  + G  C    R
Sbjct: 1232 CLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVAR 1291

Query: 1074 LC-DARCAEHGQC----KNGTCLCVSGWNGRHC-TLEGCP-----RSCAG----H-GQCR 1117
             C + +C     C    +   C C  G +G  C +  G P      SCA     H G CR
Sbjct: 1292 SCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCR 1351

Query: 1118 -VDNDGRWECKCFDGWDGPDC-------TTLKEQICDDSRDNDKDGLVDCEDPECCQSPA 1169
                   + C C  GW GP C          +E  C  +    K G   C D E C SP 
Sbjct: 1352 PAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRC-DRE-CNSPG 1409

Query: 1170 C 1170
            C
Sbjct: 1410 C 1410



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 28/214 (13%)

Query: 987  EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ------TCSCHAKWSGEDCS 1040
            E  C+C  GW G  C    +D     P C+G G             +C C   + G DCS
Sbjct: 62   EAACLCPPGWVGERCQL--EDPCHSGP-CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCS 118

Query: 1041 -KEVC-SLECGPHGRC-VGES----CSCAAGWSGEFCSVRLCDAR----CAEHGQCKN-- 1087
              + C S  C    RC VG      CSC  G+ G  C   + + R    C   G C N  
Sbjct: 119  LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTP 178

Query: 1088 GT--CLCVSGWNGRHC---TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
            G+  C C +G+ G  C    +   P  C   G CR   D  ++C C  G++G +C    +
Sbjct: 179  GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVD 238

Query: 1143 QICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
              C   R  +    VD  +   CQ P   + Q C
Sbjct: 239  D-CPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 271



 Score = 73.3 bits (172), Expect = 1e-11
 Identities = 86/329 (26%), Positives = 119/329 (36%), Gaps = 71/329 (21%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN----GECQCNPGW 930
            C +G + +G      C+C PG+ GD+C   V  C    C   G  I+      C C PG 
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGT 1152

Query: 931  KGKECSLRHDEC-------EVPDCNGHGHCVN----GKCSCVRGYKGKFC-GEI-DCPHP 977
             G  C +  D+C         P C  +G CV+     +C+C  GY G  C  +I +C   
Sbjct: 1153 LGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSG 1212

Query: 978  TC-SGH-GFCIEG-----TCVCKKGWKGADCGTM--------DKDALQCLPDCSGHGTFD 1022
             C + H   C++       C+C  G+ G  C T+         +   QC P     G   
Sbjct: 1213 ACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGL- 1271

Query: 1023 VDTQTCSCHAKWSGEDCSKEVCS---LECGPHGRCV----GESCSCAAGWSGEFC----- 1070
              T TC C   + G  C +   S   L+C     C     G  C+C  G SG  C     
Sbjct: 1272 --TFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPG 1329

Query: 1071 ------SVRLCDARCAEHGQCKNG------TCLCVSGWNGRHCTLEGCPRSCAGHGQC-- 1116
                  +     A C   G C+         C C  GW G  C         +   +C  
Sbjct: 1330 SPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPR 1389

Query: 1117 ----RVDNDGRWECKCFD---GWDGPDCT 1138
                    D R + +C     GWDG DC+
Sbjct: 1390 AACQAKRGDQRCDRECNSPGCGWDGGDCS 1418



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 37/109 (33%), Positives = 48/109 (44%), Gaps = 15/109 (13%)

Query: 1079 CAEHGQC-----KNGTCLCVSGWNGRHCTLEGCPRS--CAGHGQCR---VDNDGRWECKC 1128
            CA  G+C     +   CLC  GW G  C LE    S  CAG G C+   V    R+ C+C
Sbjct: 49   CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108

Query: 1129 FDGWDGPDCT----TLKEQICDDSRDN-DKDGLVDCEDPECCQSPACKS 1172
              G+ GPDC+     L       +R +   DG   C  P   Q  +C+S
Sbjct: 109  PRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS 157



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 58/245 (23%), Positives = 81/245 (33%), Gaps = 31/245 (12%)

Query: 884  GKGECLMGHCQCQPGFGGDDCSKSV-------CPVLCSQRGEYINGECQCNPGWKGKEC- 935
            G G  L   C C   F G  C +         CPV    +       C C PG  G  C 
Sbjct: 1266 GPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCR 1325

Query: 936  -------SLRHDECEVPDCNGHGHCVNG------KCSCVRGYKGKFCGEIDCPHPTCSGH 982
                      +  C    C   G C         +C+C +G+ G  C E     P  S  
Sbjct: 1326 SFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRC-EAPAAAPEVSEE 1384

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
              C    C  K+G +  D    + ++  C  D  G  +  V      C A       +  
Sbjct: 1385 PRCPRAACQAKRGDQRCD---RECNSPGCGWD-GGDCSLSVGDPWRQCEALQCWRLFNNS 1440

Query: 1043 VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH---GQCKNGTCLCVSGWNGR 1099
             C   C     C+ ++  C AG     C+  + +  CA+H   G+C  G      GW+G 
Sbjct: 1441 RCDPACSSPA-CLYDNFDCHAGGRERTCNP-VYEKYCADHFADGRCDQGCNTEECGWDGL 1498

Query: 1100 HCTLE 1104
             C  E
Sbjct: 1499 DCASE 1503



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 78/327 (23%), Positives = 106/327 (32%), Gaps = 69/327 (21%)

Query: 882  CSGKGEC--LMG--HCQCQPGFGG-------DDCSKSVCPVLCSQRGEYING---ECQCN 927
            C   G C  L+G   C C PG+ G       ++C    C    ++      G    C C+
Sbjct: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCH 1235

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHC---------VNGKCSCVRGYKGKFCGEI--DCPH 976
             G+ G  C      CE   C   G C         +   C C + + G  C  +   C  
Sbjct: 1236 AGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRE 1295

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKD----------ALQCLPDCSGHGTFD 1022
              C     C +      C C  G  G  C +              A  CL   S      
Sbjct: 1296 LQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPL 1355

Query: 1023 VDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESC--------------SCAAGWSGE 1068
                 C+C   W+G  C     + E     RC   +C              S   GW G 
Sbjct: 1356 APFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGG 1415

Query: 1069 FCSVRLCDA-RCAEHGQC----KNGTC--LCVSG---WNGRHCTLEGCPRSC-AGHGQCR 1117
             CS+ + D  R  E  QC     N  C   C S    ++   C   G  R+C   + +  
Sbjct: 1416 DCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYC 1475

Query: 1118 VDN--DGRWECKCFD---GWDGPDCTT 1139
             D+  DGR +  C     GWDG DC +
Sbjct: 1476 ADHFADGRCDQGCNTEECGWDGLDCAS 1502



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 41/162 (25%), Positives = 52/162 (32%), Gaps = 23/162 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C C  G+ G  C         S+        CQ   G   + C     EC  P C   G 
Sbjct: 1361 CACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRG--DQRCDR---ECNSPGCGWDG- 1414

Query: 953  CVNGKCSCVRGYKGKFCGEIDCPH--------PTCSGHGFCIEGTCVCKKGWKGADCGTM 1004
               G CS   G   + C  + C          P CS    C+     C  G +   C  +
Sbjct: 1415 ---GDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPA-CLYDNFDCHAGGRERTCNPV 1470

Query: 1005 DKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSL 1046
             +    C  D    G  D    T  C   W G DC+ EV +L
Sbjct: 1471 YEK--YCA-DHFADGRCDQGCNTEECG--WDGLDCASEVPAL 1507


>AY358892-1|AAQ89251.1|  723|Homo sapiens DLL1 protein.
          Length = 723

 Score =  120 bits (290), Expect = 6e-26
 Identities = 87/281 (30%), Positives = 129/281 (45%), Gaps = 42/281 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCSQRGEYIN--GECQCNPGWKGKECSLRHDEC-EVPDC 947
            G   C PG+ G  C++ +C   C ++  + +  GEC+C  GW+G+ C    DEC   P C
Sbjct: 208  GEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYC----DECIRYPGC 263

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCGE---IDCPHPTCSGHGFCI---EG--TCVCKKGWKG 998
              HG C    +C+C  G+ G FC +       H  C     C    +G  TC C+ G+ G
Sbjct: 264  L-HGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG 322

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVD-TQTCSCHAKWSGEDCSKEVCSLECGP---HGRC 1054
            A C  +  D     P  +G    D++ + +C+C   + G+ C     +   GP    GRC
Sbjct: 323  ATC-ELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRC 381

Query: 1055 V-----GESCSCAAGWSG-------EFCSVRLCD--ARCAEHGQCKNGTCLCVSGWNGRH 1100
                  G SC C  G+SG       ++CS   C   A+C + G      C C +G++GRH
Sbjct: 382  SDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAY--LCRCQAGFSGRH 439

Query: 1101 C--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
            C   ++ C  S CA  G CR D    + C C  G+ G +C+
Sbjct: 440  CDDNVDDCASSPCANGGTCR-DGVNDFSCTCPPGYTGRNCS 479



 Score =  109 bits (261), Expect = 2e-22
 Identities = 85/301 (28%), Positives = 129/301 (42%), Gaps = 37/301 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GC  + G C   G C+C+ G+ G  C + +    C         +C C  GW G  C
Sbjct: 226  CLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFC 285

Query: 936  SLRHDEC-EVPDCNGHGHCVN-GK----CSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
            +   + C     C     C N G+    CSC  GY G  C  G  +C    C   G C +
Sbjct: 286  NQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTD 345

Query: 988  ----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ----TCSCHAKWSGEDC 1039
                 +C C  G+ G  C   +  A+ C      +G    D+     +C C   +SG +C
Sbjct: 346  LENSYSCTCPPGFYGKIC---ELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNC 402

Query: 1040 SKEV--CSLE-CGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CAEHGQCKNG- 1088
             K++  CS   C    +CV  G++  C C AG+SG  C   + D     CA  G C++G 
Sbjct: 403  EKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGV 462

Query: 1089 ---TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQ 1143
               +C C  G+ GR+C+  +  C  +   +G    +   R+ C+C  G+ GP+C  L  +
Sbjct: 463  NDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPE 522

Query: 1144 I 1144
            +
Sbjct: 523  L 523



 Score =  103 bits (246), Expect = 1e-20
 Identities = 75/248 (30%), Positives = 110/248 (44%), Gaps = 34/248 (13%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCN-GHGHCVN-GKCSCVRGYKGKFCG 970
            C +RGE +     CNPGWKG  C+   +   +P C+  HG C   G+C C  G++G++C 
Sbjct: 204  CGERGEKV-----CNPGWKGPYCT---EPICLPGCDEQHGFCDKPGECKCRVGWQGRYCD 255

Query: 971  EIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ--- 1026
            E    +P C  HG C +   C C++GW G  C   D +       C    T     Q   
Sbjct: 256  EC-IRYPGCL-HGTCQQPWQCNCQEGWGGLFC-NQDLNYCTHHKPCKNGATCTNTGQGSY 312

Query: 1027 TCSCHAKWSGEDCSKEVCSLE---CGPHGRCV----GESCSCAAGWSGEFC--SVRLC-D 1076
            TCSC   ++G  C   +   +   C   G C       SC+C  G+ G+ C  S   C D
Sbjct: 313  TCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCAD 372

Query: 1077 ARCAEHGQCKNG-----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCF 1129
              C   G+C +      +C C  G++G +C   ++ C  S   +G   VD    + C+C 
Sbjct: 373  GPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQ 432

Query: 1130 DGWDGPDC 1137
             G+ G  C
Sbjct: 433  AGFSGRHC 440


>AL078605-2|CAB89569.1|  723|Homo sapiens delta-like 1 (Drosophila)
            protein.
          Length = 723

 Score =  120 bits (290), Expect = 6e-26
 Identities = 87/281 (30%), Positives = 129/281 (45%), Gaps = 42/281 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCSQRGEYIN--GECQCNPGWKGKECSLRHDEC-EVPDC 947
            G   C PG+ G  C++ +C   C ++  + +  GEC+C  GW+G+ C    DEC   P C
Sbjct: 208  GEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYC----DECIRYPGC 263

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCGE---IDCPHPTCSGHGFCI---EG--TCVCKKGWKG 998
              HG C    +C+C  G+ G FC +       H  C     C    +G  TC C+ G+ G
Sbjct: 264  L-HGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG 322

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVD-TQTCSCHAKWSGEDCSKEVCSLECGP---HGRC 1054
            A C  +  D     P  +G    D++ + +C+C   + G+ C     +   GP    GRC
Sbjct: 323  ATC-ELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRC 381

Query: 1055 V-----GESCSCAAGWSG-------EFCSVRLCD--ARCAEHGQCKNGTCLCVSGWNGRH 1100
                  G SC C  G+SG       ++CS   C   A+C + G      C C +G++GRH
Sbjct: 382  SDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAY--LCRCQAGFSGRH 439

Query: 1101 C--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
            C   ++ C  S CA  G CR D    + C C  G+ G +C+
Sbjct: 440  CDDNVDDCASSPCANGGTCR-DGVNDFSCTCPPGYTGRNCS 479



 Score =  109 bits (261), Expect = 2e-22
 Identities = 85/301 (28%), Positives = 129/301 (42%), Gaps = 37/301 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GC  + G C   G C+C+ G+ G  C + +    C         +C C  GW G  C
Sbjct: 226  CLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFC 285

Query: 936  SLRHDEC-EVPDCNGHGHCVN-GK----CSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
            +   + C     C     C N G+    CSC  GY G  C  G  +C    C   G C +
Sbjct: 286  NQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTD 345

Query: 988  ----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ----TCSCHAKWSGEDC 1039
                 +C C  G+ G  C   +  A+ C      +G    D+     +C C   +SG +C
Sbjct: 346  LENSYSCTCPPGFYGKIC---ELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNC 402

Query: 1040 SKEV--CSLE-CGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CAEHGQCKNG- 1088
             K++  CS   C    +CV  G++  C C AG+SG  C   + D     CA  G C++G 
Sbjct: 403  EKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGV 462

Query: 1089 ---TCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQ 1143
               +C C  G+ GR+C+  +  C  +   +G    +   R+ C+C  G+ GP+C  L  +
Sbjct: 463  NDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPE 522

Query: 1144 I 1144
            +
Sbjct: 523  L 523



 Score =  103 bits (246), Expect = 1e-20
 Identities = 75/248 (30%), Positives = 110/248 (44%), Gaps = 34/248 (13%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCN-GHGHCVN-GKCSCVRGYKGKFCG 970
            C +RGE +     CNPGWKG  C+   +   +P C+  HG C   G+C C  G++G++C 
Sbjct: 204  CGERGEKV-----CNPGWKGPYCT---EPICLPGCDEQHGFCDKPGECKCRVGWQGRYCD 255

Query: 971  EIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ--- 1026
            E    +P C  HG C +   C C++GW G  C   D +       C    T     Q   
Sbjct: 256  EC-IRYPGCL-HGTCQQPWQCNCQEGWGGLFC-NQDLNYCTHHKPCKNGATCTNTGQGSY 312

Query: 1027 TCSCHAKWSGEDCSKEVCSLE---CGPHGRCV----GESCSCAAGWSGEFC--SVRLC-D 1076
            TCSC   ++G  C   +   +   C   G C       SC+C  G+ G+ C  S   C D
Sbjct: 313  TCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCAD 372

Query: 1077 ARCAEHGQCKNG-----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCF 1129
              C   G+C +      +C C  G++G +C   ++ C  S   +G   VD    + C+C 
Sbjct: 373  GPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQ 432

Query: 1130 DGWDGPDC 1137
             G+ G  C
Sbjct: 433  AGFSGRHC 440


>AF222310-1|AAG09716.1|  723|Homo sapiens Delta1 protein.
          Length = 723

 Score =  120 bits (290), Expect = 6e-26
 Identities = 87/281 (30%), Positives = 129/281 (45%), Gaps = 42/281 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCSQRGEYIN--GECQCNPGWKGKECSLRHDEC-EVPDC 947
            G   C PG+ G  C++ +C   C ++  + +  GEC+C  GW+G+ C    DEC   P C
Sbjct: 208  GEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYC----DECIRYPGC 263

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCGE---IDCPHPTCSGHGFCI---EG--TCVCKKGWKG 998
              HG C    +C+C  G+ G FC +       H  C     C    +G  TC C+ G+ G
Sbjct: 264  L-HGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG 322

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVD-TQTCSCHAKWSGEDCSKEVCSLECGP---HGRC 1054
            A C  +  D     P  +G    D++ + +C+C   + G+ C     +   GP    GRC
Sbjct: 323  ATC-ELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRC 381

Query: 1055 V-----GESCSCAAGWSG-------EFCSVRLCD--ARCAEHGQCKNGTCLCVSGWNGRH 1100
                  G SC C  G+SG       ++CS   C   A+C + G      C C +G++GRH
Sbjct: 382  SDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAY--LCRCQAGFSGRH 439

Query: 1101 C--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
            C   ++ C  S CA  G CR D    + C C  G+ G +C+
Sbjct: 440  CDDNVDDCASSPCANGGTCR-DGVNDFSCTCPPGYTGRNCS 479



 Score =  106 bits (255), Expect = 1e-21
 Identities = 86/302 (28%), Positives = 128/302 (42%), Gaps = 39/302 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GC  + G C   G C+C+ G+ G  C + +    C         +C C  GW G  C
Sbjct: 226  CLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFC 285

Query: 936  SLRHDEC-EVPDCNGHGHCVN-GK----CSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
            +   + C     C     C N G+    CSC  GY G  C  G  +C    C   G C +
Sbjct: 286  NQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTD 345

Query: 988  ----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ----TCSCHAKWSGEDC 1039
                 +C C  G+ G  C   +  A+ C      +G    D+     +C C   +SG +C
Sbjct: 346  LENSYSCTCPPGFYGKIC---ELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNC 402

Query: 1040 SKEV--CSLE-CGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CAEHGQCKNG- 1088
             K++  CS   C    +CV  G++  C C AG+SG  C   + D     CA  G C++G 
Sbjct: 403  EKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGV 462

Query: 1089 ---TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
               +C C  G+ GR+C+  +  C  + C     C     G + C+C  G+ GP+C  L  
Sbjct: 463  NDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHG-YVCECARGYGGPNCQFLLP 521

Query: 1143 QI 1144
            ++
Sbjct: 522  EL 523



 Score =  103 bits (246), Expect = 1e-20
 Identities = 75/248 (30%), Positives = 110/248 (44%), Gaps = 34/248 (13%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCN-GHGHCVN-GKCSCVRGYKGKFCG 970
            C +RGE +     CNPGWKG  C+   +   +P C+  HG C   G+C C  G++G++C 
Sbjct: 204  CGERGEKV-----CNPGWKGPYCT---EPICLPGCDEQHGFCDKPGECKCRVGWQGRYCD 255

Query: 971  EIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ--- 1026
            E    +P C  HG C +   C C++GW G  C   D +       C    T     Q   
Sbjct: 256  EC-IRYPGCL-HGTCQQPWQCNCQEGWGGLFC-NQDLNYCTHHKPCKNGATCTNTGQGSY 312

Query: 1027 TCSCHAKWSGEDCSKEVCSLE---CGPHGRCV----GESCSCAAGWSGEFC--SVRLC-D 1076
            TCSC   ++G  C   +   +   C   G C       SC+C  G+ G+ C  S   C D
Sbjct: 313  TCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCAD 372

Query: 1077 ARCAEHGQCKNG-----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCF 1129
              C   G+C +      +C C  G++G +C   ++ C  S   +G   VD    + C+C 
Sbjct: 373  GPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQ 432

Query: 1130 DGWDGPDC 1137
             G+ G  C
Sbjct: 433  AGFSGRHC 440



 Score = 83.0 bits (196), Expect = 1e-14
 Identities = 71/232 (30%), Positives = 94/232 (40%), Gaps = 36/232 (15%)

Query: 875  THN--CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE---- 923
            TH+  C NG  C+  G+     C C+PG+ G  C   +  C P  C   G   + E    
Sbjct: 293  THHKPCKNGATCTNTGQGSYT-CSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYS 351

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG-----KCSCVRGYKGKFCGE-ID-CPH 976
            C C PG+ GK C L    C    C   G C +       C C  GY G  C + ID C  
Sbjct: 352  CTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSS 411

Query: 977  PTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTCS 1029
              CS    C++      C C+ G+ G  C   D +   C    C+  GT    V+  +C+
Sbjct: 412  SPCSNGAKCVDLGDAYLCRCQAGFSGRHC---DDNVDDCASSPCANGGTCRDGVNDFSCT 468

Query: 1030 CHAKWSGEDCSKEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL 1074
            C   ++G +CS  V   E  P       H R  G  C CA G+ G  C   L
Sbjct: 469  CPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVCECARGYGGPNCQFLL 520


>AF196571-1|AAF05834.1|  723|Homo sapiens Delta-like-1 protein
            protein.
          Length = 723

 Score =  120 bits (290), Expect = 6e-26
 Identities = 87/281 (30%), Positives = 129/281 (45%), Gaps = 42/281 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCSQRGEYIN--GECQCNPGWKGKECSLRHDEC-EVPDC 947
            G   C PG+ G  C++ +C   C ++  + +  GEC+C  GW+G+ C    DEC   P C
Sbjct: 208  GEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYC----DECIRYPGC 263

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCGE---IDCPHPTCSGHGFCI---EG--TCVCKKGWKG 998
              HG C    +C+C  G+ G FC +       H  C     C    +G  TC C+ G+ G
Sbjct: 264  L-HGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG 322

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVD-TQTCSCHAKWSGEDCSKEVCSLECGP---HGRC 1054
            A C  +  D     P  +G    D++ + +C+C   + G+ C     +   GP    GRC
Sbjct: 323  ATC-ELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRC 381

Query: 1055 V-----GESCSCAAGWSG-------EFCSVRLCD--ARCAEHGQCKNGTCLCVSGWNGRH 1100
                  G SC C  G+SG       ++CS   C   A+C + G      C C +G++GRH
Sbjct: 382  SDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAY--LCRCQAGFSGRH 439

Query: 1101 C--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
            C   ++ C  S CA  G CR D    + C C  G+ G +C+
Sbjct: 440  CDDNVDDCASSPCANGGTCR-DGVNDFSCTCPPGYTGRNCS 479



 Score =  104 bits (249), Expect = 6e-21
 Identities = 85/302 (28%), Positives = 127/302 (42%), Gaps = 39/302 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GC  + G C   G C+C+ G+ G  C + +    C         +C C  GW G  C
Sbjct: 226  CLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFC 285

Query: 936  SLRHDEC-EVPDCNGHGHCVN-GK----CSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
            +   + C     C     C N G+    CSC  GY G  C  G  +C    C   G C +
Sbjct: 286  NQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTD 345

Query: 988  ----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ----TCSCHAKWSGEDC 1039
                 +C C  G+ G  C   +  A+ C      +G    D+     +C C   +SG +C
Sbjct: 346  LENSYSCTCPPGFYGKIC---ELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNC 402

Query: 1040 SKEV--CSLE-CGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CAEHGQCKNG- 1088
             K++  CS   C    +CV  G++  C C AG+SG  C   + D     CA  G C++G 
Sbjct: 403  EKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGV 462

Query: 1089 ---TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
               +C C  G+ GR+C+  +  C  + C     C     G + C+C   + GP+C  L  
Sbjct: 463  NDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHQRGHG-YVCECARSYGGPNCQFLLP 521

Query: 1143 QI 1144
            ++
Sbjct: 522  EL 523



 Score =  103 bits (246), Expect = 1e-20
 Identities = 75/248 (30%), Positives = 110/248 (44%), Gaps = 34/248 (13%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCN-GHGHCVN-GKCSCVRGYKGKFCG 970
            C +RGE +     CNPGWKG  C+   +   +P C+  HG C   G+C C  G++G++C 
Sbjct: 204  CGERGEKV-----CNPGWKGPYCT---EPICLPGCDEQHGFCDKPGECKCRVGWQGRYCD 255

Query: 971  EIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ--- 1026
            E    +P C  HG C +   C C++GW G  C   D +       C    T     Q   
Sbjct: 256  EC-IRYPGCL-HGTCQQPWQCNCQEGWGGLFC-NQDLNYCTHHKPCKNGATCTNTGQGSY 312

Query: 1027 TCSCHAKWSGEDCSKEVCSLE---CGPHGRCV----GESCSCAAGWSGEFC--SVRLC-D 1076
            TCSC   ++G  C   +   +   C   G C       SC+C  G+ G+ C  S   C D
Sbjct: 313  TCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCAD 372

Query: 1077 ARCAEHGQCKNG-----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCF 1129
              C   G+C +      +C C  G++G +C   ++ C  S   +G   VD    + C+C 
Sbjct: 373  GPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQ 432

Query: 1130 DGWDGPDC 1137
             G+ G  C
Sbjct: 433  AGFSGRHC 440



 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 70/232 (30%), Positives = 93/232 (40%), Gaps = 36/232 (15%)

Query: 875  THN--CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE---- 923
            TH+  C NG  C+  G+     C C+PG+ G  C   +  C P  C   G   + E    
Sbjct: 293  THHKPCKNGATCTNTGQGSYT-CSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYS 351

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG-----KCSCVRGYKGKFCGE-ID-CPH 976
            C C PG+ GK C L    C    C   G C +       C C  GY G  C + ID C  
Sbjct: 352  CTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSS 411

Query: 977  PTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTCS 1029
              CS    C++      C C+ G+ G  C   D +   C    C+  GT    V+  +C+
Sbjct: 412  SPCSNGAKCVDLGDAYLCRCQAGFSGRHC---DDNVDDCASSPCANGGTCRDGVNDFSCT 468

Query: 1030 CHAKWSGEDCSKEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL 1074
            C   ++G +CS  V   E  P       H R  G  C CA  + G  C   L
Sbjct: 469  CPPGYTGRNCSAPVSRCEHAPCHNGATCHQRGHGYVCECARSYGGPNCQFLL 520


>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
          Length = 2321

 Score =  120 bits (290), Expect = 6e-26
 Identities = 91/284 (32%), Positives = 116/284 (40%), Gaps = 44/284 (15%)

Query: 893  CQCQPGFGG-------DDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKECSLRHDECEV 944
            C+C  G  G       DDC+ + C     + G  IN  +C C PG+ G  C++  +EC  
Sbjct: 606  CRCPSGTTGVNCEVNIDDCASNPCTFGVCRDG--INRYDCVCQPGFTGPLCNVEINECAS 663

Query: 945  PDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIEG----TCVCKK 994
              C   G CV+G    +C C  G     C      C H  CS HG C +      CVC+ 
Sbjct: 664  SPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCS-HGICYDAPGGFRCVCEP 722

Query: 995  GWKGADCG-TMDKDALQCLPDCSGHGTFDVDTQ--TCSCHAKWSGEDCS-KEVCSLE-CG 1049
            GW G  C  ++ +DA +  P C   GT   D     C+C     G  C     C+   C 
Sbjct: 723  GWSGPRCSQSLARDACESQP-CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCE 781

Query: 1050 PHGRCVGES-----CSCAAGWSGEFC--SVRLC--DARCAEHGQCKN----GTCLCVSGW 1096
              GRC         CSC  GW G  C   V  C   A C  HG C N     +C C  G+
Sbjct: 782  HGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY 841

Query: 1097 NGRHC--TLEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             G  C   +  C P  C   G C+ D  G + C C  G+ GP C
Sbjct: 842  TGPSCDQDINDCDPNPCLNGGSCQ-DGVGSFSCSCLPGFAGPRC 884



 Score =  116 bits (279), Expect = 1e-24
 Identities = 100/356 (28%), Positives = 136/356 (38%), Gaps = 52/356 (14%)

Query: 872  EEMTHNCPNG-CSGKGECL--MGH--CQCQPGFGG-------DDCSKSVCPV--LCSQRG 917
            E   + C +G C  +  CL  +G   C C  GF G       D+C  S C    +C  R 
Sbjct: 429  ETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDR- 487

Query: 918  EYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-E 971
              +NG  C C  G+ G  C L  DEC    C     CV+     +C C  G++G  C   
Sbjct: 488  --VNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRN 545

Query: 972  IDCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQ 1026
            +D   P    HG C++G    +C C  G+ G  C +   D  +  P   G    D VD  
Sbjct: 546  VDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCES-QVDECRSQPCRHGGKCLDLVDKY 604

Query: 1027 TCSCHAKWSGEDCSKEV--CSLECGPHGRCVG----ESCSCAAGWSGEFCSVRL---CDA 1077
             C C +  +G +C   +  C+      G C        C C  G++G  C+V +     +
Sbjct: 605  LCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASS 664

Query: 1078 RCAEHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDG 1131
             C E G C +G     CLC  G     C      C      HG C  D  G + C C  G
Sbjct: 665  PCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC-YDAPGGFRCVCEPG 723

Query: 1132 WDGPDCT------TLKEQICDDSRDNDKDGL-VDCEDPECCQSPACKSSQLCVSSP 1180
            W GP C+        + Q C        DG+   C  P   Q   C+    C  +P
Sbjct: 724  WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP 779



 Score =  113 bits (273), Expect = 7e-24
 Identities = 96/317 (30%), Positives = 129/317 (40%), Gaps = 58/317 (18%)

Query: 872  EEMTHNCPNGCSGKGECLMG--------HCQCQPGFGGDDCS------KSVCP--VLCS- 914
            E+  H+ P  C+G+G C            C+C  GF G DCS       S C     CS 
Sbjct: 79   EDPCHSGP--CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSV 136

Query: 915  -QRGEYINGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVNG----KCSCVRGYKGKF 968
               G ++   C C PG++G+ C    DEC V + C   G C+N     +C C  GY G  
Sbjct: 137  GPDGRFL---CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPL 193

Query: 969  CGE--IDCPHPTCSGHGFCIEG-----TCVCKKGWKGADC--GTMDKDALQCLPDCSGHG 1019
            C    + C    C   G C +       C C  G++G +C     D    +CL    G  
Sbjct: 194  CENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLN--GGTC 251

Query: 1020 TFDVDTQTCSCHAKWSGEDCSKEV--CSLE---CGPHGRCV----GESCSCAAGWSGEFC 1070
               V+T  C C  +W+G+ C+++V  C L+   C   G C     G SC C  GW+GE C
Sbjct: 252  VDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESC 311

Query: 1071 SVRLCD---ARCAEHGQCKNGT----CLCVSGWNGRHCTLEGCPRSCAGHGQCRVDN--- 1120
            S  + D   A C     C +      C C  G  G  C L+    S   H     D    
Sbjct: 312  SQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPV 371

Query: 1121 DGRWECKCFDGWDGPDC 1137
            +GR  C C  G+ G  C
Sbjct: 372  NGRAICTCPPGFTGGAC 388



 Score =  106 bits (255), Expect = 1e-21
 Identities = 89/290 (30%), Positives = 121/290 (41%), Gaps = 46/290 (15%)

Query: 893  CQCQPGFGGDDCSKSV--CPV--LCSQRGEYING----ECQCNPGWKGKECSLRHDECEV 944
            C C PG+ G  C   V  C V   C   G  +N      CQC  G+ G  C      C  
Sbjct: 144  CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAP 203

Query: 945  PDCNGHGHC-----VNGKCSCVRGYKGKFCGEI---DCPHPTCSGHGFCIEGT----CVC 992
              C   G C     +   C+C+ G++G+ C E+   DCP   C   G C++G     C C
Sbjct: 204  SPCRNGGTCRQSGDLTYDCACLPGFEGQNC-EVNVDDCPGHRCLNGGTCVDGVNTYNCQC 262

Query: 993  KKGWKGADCGTMDKDALQCLPD-CSGHGT-FD-VDTQTCSCHAKWSGEDCSKEV--CSLE 1047
               W G  C T D D  Q  P+ C   GT F+ +   +C C   W+GE CS+ +  C+  
Sbjct: 263  PPEWTGQFC-TEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATA 321

Query: 1048 CGPHG-----RCVGESCSCAAGWSGEFCSVR-LCDAR-CAEHGQCK----NGT--CLCVS 1094
               HG     R     C+C  G +G  C +   C +  C E   C     NG   C C  
Sbjct: 322  VCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPP 381

Query: 1095 GWNGRHCT--LEGCP---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            G+ G  C   ++ C      C   G+C V+  G + C+C  G+ GP C T
Sbjct: 382  GFTGGACDQDVDECSIGANPCEHLGRC-VNTQGSFLCQCGRGYTGPRCET 430



 Score =  103 bits (248), Expect = 7e-21
 Identities = 89/297 (29%), Positives = 113/297 (38%), Gaps = 42/297 (14%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYING----ECQCNPGWK 931
            C NG     +     C+C  GF G  C ++V  C       G  ++G     C C PG+ 
Sbjct: 516  CRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYT 575

Query: 932  GKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFCGEI---DCPHPTCSGHGF 984
            G  C  + DEC    C   G C++      C C  G  G  C E+   DC    C+  G 
Sbjct: 576  GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNC-EVNIDDCASNPCT-FGV 633

Query: 985  CIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CSCHAKWSGE 1037
            C +G     CVC+ G+ G  C     +  +C     G G   VD +    C C       
Sbjct: 634  CRDGINRYDCVCQPGFTGPLCNV---EINECASSPCGEGGSCVDGENGFRCLCPPGSLPP 690

Query: 1038 DC--SKEVCSLECGPHGRCV----GESCSCAAGWSGEFCSVRL----CDAR-CAEHGQCK 1086
             C      C+ E   HG C     G  C C  GWSG  CS  L    C+++ C   G C 
Sbjct: 691  LCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCS 750

Query: 1087 NG----TCLCVSGWNGRHC-TLEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            +      C C  G  GR C  L  C P  C   G+C         C C  GW GP C
Sbjct: 751  SDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRC 807



 Score =  103 bits (246), Expect = 1e-20
 Identities = 86/310 (27%), Positives = 119/310 (38%), Gaps = 46/310 (14%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG--------KCSCVRGYKGKFCGEID-C 974
            C C PGW G+ C L  D C    C G G C +          C C RG++G  C   D C
Sbjct: 65   CLCPPGWVGERCQL-EDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPC 123

Query: 975  PHPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ--- 1026
                C+    C  G      C C  G++G  C + D D  +    C  HG   ++T    
Sbjct: 124  LSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-DVDECRVGEPCR-HGGTCLNTPGSF 181

Query: 1027 TCSCHAKWSGEDCSKEV--CS-LECGPHGRC-----VGESCSCAAGWSGEFCSVRLCDA- 1077
             C C A ++G  C      C+   C   G C     +   C+C  G+ G+ C V + D  
Sbjct: 182  RCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCP 241

Query: 1078 --RCAEHGQCKNG----TCLCVSGWNGRHCT--LEGC---PRSCAGHGQCRVDNDGRWEC 1126
              RC   G C +G     C C   W G+ CT  ++ C   P +C   G C  +  G   C
Sbjct: 242  GHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTC-FNTLGGHSC 300

Query: 1127 KCFDGWDGPDCT----TLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSPK 1181
             C +GW G  C+         +C   +  +D+     C  P       C     CVS+P 
Sbjct: 301  VCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPC 360

Query: 1182 PTDILLRKQP 1191
              D +    P
Sbjct: 361  HEDAICDTNP 370



 Score = 97.5 bits (232), Expect = 6e-19
 Identities = 92/313 (29%), Positives = 116/313 (37%), Gaps = 49/313 (15%)

Query: 879  PNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVLCSQRG------EYINGECQCNP 928
            PN C   G C  G     C C PGF G  C++ V   L +  G         +  C C P
Sbjct: 855  PNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPP 914

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPHPTCSGH 982
            G+ G  C     +C    C   G CV+G     C C  GY G  C  E D C    C   
Sbjct: 915  GYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHG 974

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
            G C        C C + + G  C T+  D     P C   G        C C   WSG  
Sbjct: 975  GVCSAAHPGFRCTCLESFTGPQCQTL-VDWCSRQP-CQNGGRCVQTGAYCLCPPGWSGRL 1032

Query: 1039 CS------KEVCS-----LE--CGPHGRCVGES----CSCAAGWSGEFC--SVRLCDARC 1079
            C       +E  +     LE  C   G+CV E     C C  G +G  C   V  C A+ 
Sbjct: 1033 CDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQP 1092

Query: 1080 AEHGQCKNG-----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
             +HG    G      C C+ G+NG +C   ++ C      HG   +D   R+ C C  G 
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGT 1152

Query: 1133 DGPDCTTLKEQIC 1145
             G  C  + E  C
Sbjct: 1153 LGVLC-EINEDDC 1164



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 89/305 (29%), Positives = 125/305 (40%), Gaps = 53/305 (17%)

Query: 882  CSGKGECLM-----GHCQCQPGFGGDDCS-KSVC-PVLCSQRG----EYING----ECQC 926
            C+  G C         C C PG+ G+ C  +  C    C+ RG      + G     C+C
Sbjct: 49   CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108

Query: 927  NPGWKGKECSLRHDECEVPDCNGHGHCVNGK-----CSCVRGYKGKFC-GEID-C-PHPT 978
              G++G +CSL  D C    C     C  G      CSC  GY+G+ C  ++D C     
Sbjct: 109  PRGFRGPDCSL-PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 167

Query: 979  CSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVD---TQTCSC 1030
            C   G C+   G+  C C  G+ G  C   +  A+ C P  C   GT       T  C+C
Sbjct: 168  CRHGGTCLNTPGSFRCQCPAGYTGPLC---ENPAVPCAPSPCRNGGTCRQSGDLTYDCAC 224

Query: 1031 HAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR--- 1078
               + G++C   V  C    C   G CV      +C C   W+G+FC+  V  C  +   
Sbjct: 225  LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNA 284

Query: 1079 CAEHGQCKN----GTCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
            C   G C N     +C+CV+GW G  C+  ++ C  +   HG    D    + C C  G 
Sbjct: 285  CHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGK 344

Query: 1133 DGPDC 1137
             G  C
Sbjct: 345  TGLLC 349



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 88/303 (29%), Positives = 118/303 (38%), Gaps = 51/303 (16%)

Query: 882  CSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---------CSQRGEYINGECQCNP 928
            C   G CL       CQC  G+ G  C     P           C Q G+ +  +C C P
Sbjct: 168  CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGD-LTYDCACLP 226

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP-HP-TCS 980
            G++G+ C +  D+C    C   G CV+G     C C   + G+FC E +D C   P  C 
Sbjct: 227  GFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACH 286

Query: 981  GHGFCIE----GTCVCKKGWKGADCGTMDKDALQ--CLPDCSGHGTFDVDTQTCSCHAKW 1034
              G C       +CVC  GW G  C     D     C    + H    V +  C+C    
Sbjct: 287  NGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDR--VASFYCACPMGK 344

Query: 1035 SGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFC--SVRLCD--ARCAEH 1082
            +G  C   + C S  C     C      G + C+C  G++G  C   V  C   A   EH
Sbjct: 345  TGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEH 404

Query: 1083 -GQCKN--GT--CLCVSGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
             G+C N  G+  C C  G+ G  C     E     C     C +D  G++ C C  G+ G
Sbjct: 405  LGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATC-LDRIGQFTCICMAGFTG 463

Query: 1135 PDC 1137
              C
Sbjct: 464  TYC 466



 Score = 83.0 bits (196), Expect = 1e-14
 Identities = 102/361 (28%), Positives = 131/361 (36%), Gaps = 77/361 (21%)

Query: 882  CSGKGECL----MGHCQCQPGFGGDDCSKSVCPVL---CSQRGE---YINGE-CQCNPGW 930
            C   G+C+      +C C  G  G  C + V P L   C   G    Y+ G  C+C PG+
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY 1114

Query: 931  KGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFC--GEIDC-------PHP 977
             G  C    DEC    C   G C++      CSC  G  G  C   E DC         P
Sbjct: 1115 NGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1174

Query: 978  TCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDTQ-----T 1027
             C  +G C++      C C  G+ G  C   + D  +C    C    T D          
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGYTGLRC---EADINECRSGACHAAHTRDCLQDPGGGFR 1231

Query: 1028 CSCHAKWSGEDCSKEVCSLE---CGPHGRC---------VGESCSCAAGWSGEFCS--VR 1073
            C CHA +SG  C   +   E   C   G+C         +  +C CA  + G  C    R
Sbjct: 1232 CLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVAR 1291

Query: 1074 LC-DARCAEHGQC----KNGTCLCVSGWNGRHC-TLEGCP-----RSCAG----H-GQCR 1117
             C + +C     C    +   C C  G +G  C +  G P      SCA     H G CR
Sbjct: 1292 SCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCR 1351

Query: 1118 -VDNDGRWECKCFDGWDGPDC-------TTLKEQICDDSRDNDKDGLVDCEDPECCQSPA 1169
                   + C C  GW GP C          +E  C  +    K G   C D E C SP 
Sbjct: 1352 PAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRC-DRE-CNSPG 1409

Query: 1170 C 1170
            C
Sbjct: 1410 C 1410



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 28/214 (13%)

Query: 987  EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ------TCSCHAKWSGEDCS 1040
            E  C+C  GW G  C    +D     P C+G G             +C C   + G DCS
Sbjct: 62   EAACLCPPGWVGERCQL--EDPCHSGP-CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCS 118

Query: 1041 -KEVC-SLECGPHGRC-VGES----CSCAAGWSGEFCSVRLCDAR----CAEHGQCKN-- 1087
              + C S  C    RC VG      CSC  G+ G  C   + + R    C   G C N  
Sbjct: 119  LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTP 178

Query: 1088 GT--CLCVSGWNGRHC---TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
            G+  C C +G+ G  C    +   P  C   G CR   D  ++C C  G++G +C    +
Sbjct: 179  GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVD 238

Query: 1143 QICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
              C   R  +    VD  +   CQ P   + Q C
Sbjct: 239  D-CPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 271



 Score = 73.3 bits (172), Expect = 1e-11
 Identities = 86/329 (26%), Positives = 119/329 (36%), Gaps = 71/329 (21%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN----GECQCNPGW 930
            C +G + +G      C+C PG+ GD+C   V  C    C   G  I+      C C PG 
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGT 1152

Query: 931  KGKECSLRHDEC-------EVPDCNGHGHCVN----GKCSCVRGYKGKFC-GEI-DCPHP 977
             G  C +  D+C         P C  +G CV+     +C+C  GY G  C  +I +C   
Sbjct: 1153 LGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSG 1212

Query: 978  TC-SGH-GFCIEG-----TCVCKKGWKGADCGTM--------DKDALQCLPDCSGHGTFD 1022
             C + H   C++       C+C  G+ G  C T+         +   QC P     G   
Sbjct: 1213 ACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGL- 1271

Query: 1023 VDTQTCSCHAKWSGEDCSKEVCS---LECGPHGRCV----GESCSCAAGWSGEFC----- 1070
              T TC C   + G  C +   S   L+C     C     G  C+C  G SG  C     
Sbjct: 1272 --TFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPG 1329

Query: 1071 ------SVRLCDARCAEHGQCKNG------TCLCVSGWNGRHCTLEGCPRSCAGHGQC-- 1116
                  +     A C   G C+         C C  GW G  C         +   +C  
Sbjct: 1330 SPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPR 1389

Query: 1117 ----RVDNDGRWECKCFD---GWDGPDCT 1138
                    D R + +C     GWDG DC+
Sbjct: 1390 AACQAKRGDQRCDRECNSPGCGWDGGDCS 1418



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 37/109 (33%), Positives = 48/109 (44%), Gaps = 15/109 (13%)

Query: 1079 CAEHGQC-----KNGTCLCVSGWNGRHCTLEGCPRS--CAGHGQCR---VDNDGRWECKC 1128
            CA  G+C     +   CLC  GW G  C LE    S  CAG G C+   V    R+ C+C
Sbjct: 49   CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108

Query: 1129 FDGWDGPDCT----TLKEQICDDSRDN-DKDGLVDCEDPECCQSPACKS 1172
              G+ GPDC+     L       +R +   DG   C  P   Q  +C+S
Sbjct: 109  PRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS 157



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 58/245 (23%), Positives = 81/245 (33%), Gaps = 31/245 (12%)

Query: 884  GKGECLMGHCQCQPGFGGDDCSKSV-------CPVLCSQRGEYINGECQCNPGWKGKEC- 935
            G G  L   C C   F G  C +         CPV    +       C C PG  G  C 
Sbjct: 1266 GPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCR 1325

Query: 936  -------SLRHDECEVPDCNGHGHCVNG------KCSCVRGYKGKFCGEIDCPHPTCSGH 982
                      +  C    C   G C         +C+C +G+ G  C E     P  S  
Sbjct: 1326 SFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRC-EAPAAAPEVSEE 1384

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
              C    C  K+G +  D    + ++  C  D  G  +  V      C A       +  
Sbjct: 1385 PRCPRAACQAKRGDQRCD---RECNSPGCGWD-GGDCSLSVGDPWRQCEALQCWRLFNNS 1440

Query: 1043 VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH---GQCKNGTCLCVSGWNGR 1099
             C   C     C+ ++  C AG     C+  + +  CA+H   G+C  G      GW+G 
Sbjct: 1441 RCDPACSSPA-CLYDNFDCHAGGRERTCNP-VYEKYCADHFADGRCDQGCNTEECGWDGL 1498

Query: 1100 HCTLE 1104
             C  E
Sbjct: 1499 DCASE 1503



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 78/327 (23%), Positives = 106/327 (32%), Gaps = 69/327 (21%)

Query: 882  CSGKGEC--LMG--HCQCQPGFGG-------DDCSKSVCPVLCSQRGEYING---ECQCN 927
            C   G C  L+G   C C PG+ G       ++C    C    ++      G    C C+
Sbjct: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCH 1235

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHC---------VNGKCSCVRGYKGKFCGEI--DCPH 976
             G+ G  C      CE   C   G C         +   C C + + G  C  +   C  
Sbjct: 1236 AGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRE 1295

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKD----------ALQCLPDCSGHGTFD 1022
              C     C +      C C  G  G  C +              A  CL   S      
Sbjct: 1296 LQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPL 1355

Query: 1023 VDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESC--------------SCAAGWSGE 1068
                 C+C   W+G  C     + E     RC   +C              S   GW G 
Sbjct: 1356 APFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGG 1415

Query: 1069 FCSVRLCDA-RCAEHGQC----KNGTC--LCVSG---WNGRHCTLEGCPRSC-AGHGQCR 1117
             CS+ + D  R  E  QC     N  C   C S    ++   C   G  R+C   + +  
Sbjct: 1416 DCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYC 1475

Query: 1118 VDN--DGRWECKCFD---GWDGPDCTT 1139
             D+  DGR +  C     GWDG DC +
Sbjct: 1476 ADHFADGRCDQGCNTEECGWDGLDCAS 1502



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 41/162 (25%), Positives = 52/162 (32%), Gaps = 23/162 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C C  G+ G  C         S+        CQ   G   + C     EC  P C   G 
Sbjct: 1361 CACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRG--DQRCDR---ECNSPGCGWDG- 1414

Query: 953  CVNGKCSCVRGYKGKFCGEIDCPH--------PTCSGHGFCIEGTCVCKKGWKGADCGTM 1004
               G CS   G   + C  + C          P CS    C+     C  G +   C  +
Sbjct: 1415 ---GDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPA-CLYDNFDCHAGGRERTCNPV 1470

Query: 1005 DKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSL 1046
             +    C  D    G  D    T  C   W G DC+ EV +L
Sbjct: 1471 YEK--YCA-DHFADGRCDQGCNTEECG--WDGLDCASEVPAL 1507


>AF003522-1|AAB61286.1|  723|Homo sapiens Delta protein.
          Length = 723

 Score =  120 bits (290), Expect = 6e-26
 Identities = 87/281 (30%), Positives = 129/281 (45%), Gaps = 42/281 (14%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCSQRGEYIN--GECQCNPGWKGKECSLRHDEC-EVPDC 947
            G   C PG+ G  C++ +C   C ++  + +  GEC+C  GW+G+ C    DEC   P C
Sbjct: 208  GEKVCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYC----DECIRYPGC 263

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCGE---IDCPHPTCSGHGFCI---EG--TCVCKKGWKG 998
              HG C    +C+C  G+ G FC +       H  C     C    +G  TC C+ G+ G
Sbjct: 264  L-HGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG 322

Query: 999  ADCGTMDKDALQCLPDCSGHGTFDVD-TQTCSCHAKWSGEDCSKEVCSLECGP---HGRC 1054
            A C  +  D     P  +G    D++ + +C+C   + G+ C     +   GP    GRC
Sbjct: 323  ATC-ELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRC 381

Query: 1055 V-----GESCSCAAGWSG-------EFCSVRLCD--ARCAEHGQCKNGTCLCVSGWNGRH 1100
                  G SC C  G+SG       ++CS   C   A+C + G      C C +G++GRH
Sbjct: 382  SDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAY--LCRCQAGFSGRH 439

Query: 1101 C--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
            C   ++ C  S CA  G CR D    + C C  G+ G +C+
Sbjct: 440  CDDNVDDCASSPCANGGTCR-DGVNDFSCTCPPGYTGRNCS 479



 Score =  106 bits (255), Expect = 1e-21
 Identities = 86/302 (28%), Positives = 128/302 (42%), Gaps = 39/302 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GC  + G C   G C+C+ G+ G  C + +    C         +C C  GW G  C
Sbjct: 226  CLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFC 285

Query: 936  SLRHDEC-EVPDCNGHGHCVN-GK----CSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
            +   + C     C     C N G+    CSC  GY G  C  G  +C    C   G C +
Sbjct: 286  NQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTD 345

Query: 988  ----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ----TCSCHAKWSGEDC 1039
                 +C C  G+ G  C   +  A+ C      +G    D+     +C C   +SG +C
Sbjct: 346  LENSYSCTCPPGFYGKIC---ELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNC 402

Query: 1040 SKEV--CSLE-CGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CAEHGQCKNG- 1088
             K++  CS   C    +CV  G++  C C AG+SG  C   + D     CA  G C++G 
Sbjct: 403  EKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGV 462

Query: 1089 ---TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
               +C C  G+ GR+C+  +  C  + C     C     G + C+C  G+ GP+C  L  
Sbjct: 463  NDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHG-YVCECARGYGGPNCQFLLP 521

Query: 1143 QI 1144
            ++
Sbjct: 522  EL 523



 Score =  103 bits (246), Expect = 1e-20
 Identities = 75/248 (30%), Positives = 110/248 (44%), Gaps = 34/248 (13%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCN-GHGHCVN-GKCSCVRGYKGKFCG 970
            C +RGE +     CNPGWKG  C+   +   +P C+  HG C   G+C C  G++G++C 
Sbjct: 204  CGERGEKV-----CNPGWKGPYCT---EPICLPGCDEQHGFCDKPGECKCRVGWQGRYCD 255

Query: 971  EIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ--- 1026
            E    +P C  HG C +   C C++GW G  C   D +       C    T     Q   
Sbjct: 256  EC-IRYPGCL-HGTCQQPWQCNCQEGWGGLFC-NQDLNYCTHHKPCKNGATCTNTGQGSY 312

Query: 1027 TCSCHAKWSGEDCSKEVCSLE---CGPHGRCV----GESCSCAAGWSGEFC--SVRLC-D 1076
            TCSC   ++G  C   +   +   C   G C       SC+C  G+ G+ C  S   C D
Sbjct: 313  TCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCAD 372

Query: 1077 ARCAEHGQCKNG-----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCF 1129
              C   G+C +      +C C  G++G +C   ++ C  S   +G   VD    + C+C 
Sbjct: 373  GPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQ 432

Query: 1130 DGWDGPDC 1137
             G+ G  C
Sbjct: 433  AGFSGRHC 440



 Score = 83.0 bits (196), Expect = 1e-14
 Identities = 71/232 (30%), Positives = 94/232 (40%), Gaps = 36/232 (15%)

Query: 875  THN--CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE---- 923
            TH+  C NG  C+  G+     C C+PG+ G  C   +  C P  C   G   + E    
Sbjct: 293  THHKPCKNGATCTNTGQGSYT-CSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYS 351

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG-----KCSCVRGYKGKFCGE-ID-CPH 976
            C C PG+ GK C L    C    C   G C +       C C  GY G  C + ID C  
Sbjct: 352  CTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSS 411

Query: 977  PTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTCS 1029
              CS    C++      C C+ G+ G  C   D +   C    C+  GT    V+  +C+
Sbjct: 412  SPCSNGAKCVDLGDAYLCRCQAGFSGRHC---DDNVDDCASSPCANGGTCRDGVNDFSCT 468

Query: 1030 CHAKWSGEDCSKEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL 1074
            C   ++G +CS  V   E  P       H R  G  C CA G+ G  C   L
Sbjct: 469  CPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHGYVCECARGYGGPNCQFLL 520


>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
          Length = 2281

 Score =  120 bits (290), Expect = 6e-26
 Identities = 91/284 (32%), Positives = 116/284 (40%), Gaps = 44/284 (15%)

Query: 893  CQCQPGFGG-------DDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKECSLRHDECEV 944
            C+C  G  G       DDC+ + C     + G  IN  +C C PG+ G  C++  +EC  
Sbjct: 566  CRCPSGTTGVNCEVNIDDCASNPCTFGVCRDG--INRYDCVCQPGFTGPLCNVEINECAS 623

Query: 945  PDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIEG----TCVCKK 994
              C   G CV+G    +C C  G     C      C H  CS HG C +      CVC+ 
Sbjct: 624  SPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCS-HGICYDAPGGFRCVCEP 682

Query: 995  GWKGADCG-TMDKDALQCLPDCSGHGTFDVDTQ--TCSCHAKWSGEDCS-KEVCSLE-CG 1049
            GW G  C  ++ +DA +  P C   GT   D     C+C     G  C     C+   C 
Sbjct: 683  GWSGPRCSQSLARDACESQP-CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCE 741

Query: 1050 PHGRCVGES-----CSCAAGWSGEFC--SVRLC--DARCAEHGQCKN----GTCLCVSGW 1096
              GRC         CSC  GW G  C   V  C   A C  HG C N     +C C  G+
Sbjct: 742  HGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY 801

Query: 1097 NGRHC--TLEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             G  C   +  C P  C   G C+ D  G + C C  G+ GP C
Sbjct: 802  TGPSCDQDINDCDPNPCLNGGSCQ-DGVGSFSCSCLPGFAGPRC 844



 Score =  116 bits (279), Expect = 1e-24
 Identities = 100/356 (28%), Positives = 136/356 (38%), Gaps = 52/356 (14%)

Query: 872  EEMTHNCPNG-CSGKGECL--MGH--CQCQPGFGG-------DDCSKSVCPV--LCSQRG 917
            E   + C +G C  +  CL  +G   C C  GF G       D+C  S C    +C  R 
Sbjct: 389  ETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDR- 447

Query: 918  EYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-E 971
              +NG  C C  G+ G  C L  DEC    C     CV+     +C C  G++G  C   
Sbjct: 448  --VNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRN 505

Query: 972  IDCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQ 1026
            +D   P    HG C++G    +C C  G+ G  C +   D  +  P   G    D VD  
Sbjct: 506  VDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCES-QVDECRSQPCRHGGKCLDLVDKY 564

Query: 1027 TCSCHAKWSGEDCSKEV--CSLECGPHGRCVG----ESCSCAAGWSGEFCSVRL---CDA 1077
             C C +  +G +C   +  C+      G C        C C  G++G  C+V +     +
Sbjct: 565  LCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASS 624

Query: 1078 RCAEHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDG 1131
             C E G C +G     CLC  G     C      C      HG C  D  G + C C  G
Sbjct: 625  PCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC-YDAPGGFRCVCEPG 683

Query: 1132 WDGPDCT------TLKEQICDDSRDNDKDGL-VDCEDPECCQSPACKSSQLCVSSP 1180
            W GP C+        + Q C        DG+   C  P   Q   C+    C  +P
Sbjct: 684  WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP 739



 Score =  113 bits (273), Expect = 7e-24
 Identities = 96/317 (30%), Positives = 129/317 (40%), Gaps = 58/317 (18%)

Query: 872  EEMTHNCPNGCSGKGECLMG--------HCQCQPGFGGDDCS------KSVCP--VLCS- 914
            E+  H+ P  C+G+G C            C+C  GF G DCS       S C     CS 
Sbjct: 39   EDPCHSGP--CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSV 96

Query: 915  -QRGEYINGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVNG----KCSCVRGYKGKF 968
               G ++   C C PG++G+ C    DEC V + C   G C+N     +C C  GY G  
Sbjct: 97   GPDGRFL---CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPL 153

Query: 969  CGE--IDCPHPTCSGHGFCIEG-----TCVCKKGWKGADC--GTMDKDALQCLPDCSGHG 1019
            C    + C    C   G C +       C C  G++G +C     D    +CL    G  
Sbjct: 154  CENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLN--GGTC 211

Query: 1020 TFDVDTQTCSCHAKWSGEDCSKEV--CSLE---CGPHGRCV----GESCSCAAGWSGEFC 1070
               V+T  C C  +W+G+ C+++V  C L+   C   G C     G SC C  GW+GE C
Sbjct: 212  VDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESC 271

Query: 1071 SVRLCD---ARCAEHGQCKNGT----CLCVSGWNGRHCTLEGCPRSCAGHGQCRVDN--- 1120
            S  + D   A C     C +      C C  G  G  C L+    S   H     D    
Sbjct: 272  SQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPV 331

Query: 1121 DGRWECKCFDGWDGPDC 1137
            +GR  C C  G+ G  C
Sbjct: 332  NGRAICTCPPGFTGGAC 348



 Score =  106 bits (255), Expect = 1e-21
 Identities = 89/290 (30%), Positives = 121/290 (41%), Gaps = 46/290 (15%)

Query: 893  CQCQPGFGGDDCSKSV--CPV--LCSQRGEYING----ECQCNPGWKGKECSLRHDECEV 944
            C C PG+ G  C   V  C V   C   G  +N      CQC  G+ G  C      C  
Sbjct: 104  CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAP 163

Query: 945  PDCNGHGHC-----VNGKCSCVRGYKGKFCGEI---DCPHPTCSGHGFCIEGT----CVC 992
              C   G C     +   C+C+ G++G+ C E+   DCP   C   G C++G     C C
Sbjct: 164  SPCRNGGTCRQSGDLTYDCACLPGFEGQNC-EVNVDDCPGHRCLNGGTCVDGVNTYNCQC 222

Query: 993  KKGWKGADCGTMDKDALQCLPD-CSGHGT-FD-VDTQTCSCHAKWSGEDCSKEV--CSLE 1047
               W G  C T D D  Q  P+ C   GT F+ +   +C C   W+GE CS+ +  C+  
Sbjct: 223  PPEWTGQFC-TEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATA 281

Query: 1048 CGPHG-----RCVGESCSCAAGWSGEFCSVR-LCDAR-CAEHGQCK----NGT--CLCVS 1094
               HG     R     C+C  G +G  C +   C +  C E   C     NG   C C  
Sbjct: 282  VCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPP 341

Query: 1095 GWNGRHCT--LEGCP---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            G+ G  C   ++ C      C   G+C V+  G + C+C  G+ GP C T
Sbjct: 342  GFTGGACDQDVDECSIGANPCEHLGRC-VNTQGSFLCQCGRGYTGPRCET 390



 Score =  103 bits (248), Expect = 7e-21
 Identities = 89/297 (29%), Positives = 113/297 (38%), Gaps = 42/297 (14%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYING----ECQCNPGWK 931
            C NG     +     C+C  GF G  C ++V  C       G  ++G     C C PG+ 
Sbjct: 476  CRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYT 535

Query: 932  GKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFCGEI---DCPHPTCSGHGF 984
            G  C  + DEC    C   G C++      C C  G  G  C E+   DC    C+  G 
Sbjct: 536  GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNC-EVNIDDCASNPCT-FGV 593

Query: 985  CIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CSCHAKWSGE 1037
            C +G     CVC+ G+ G  C     +  +C     G G   VD +    C C       
Sbjct: 594  CRDGINRYDCVCQPGFTGPLCNV---EINECASSPCGEGGSCVDGENGFRCLCPPGSLPP 650

Query: 1038 DC--SKEVCSLECGPHGRCV----GESCSCAAGWSGEFCSVRL----CDAR-CAEHGQCK 1086
             C      C+ E   HG C     G  C C  GWSG  CS  L    C+++ C   G C 
Sbjct: 651  LCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCS 710

Query: 1087 NG----TCLCVSGWNGRHC-TLEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            +      C C  G  GR C  L  C P  C   G+C         C C  GW GP C
Sbjct: 711  SDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRC 767



 Score =  103 bits (246), Expect = 1e-20
 Identities = 86/310 (27%), Positives = 119/310 (38%), Gaps = 46/310 (14%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG--------KCSCVRGYKGKFCGEID-C 974
            C C PGW G+ C L  D C    C G G C +          C C RG++G  C   D C
Sbjct: 25   CLCPPGWVGERCQL-EDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPC 83

Query: 975  PHPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ--- 1026
                C+    C  G      C C  G++G  C + D D  +    C  HG   ++T    
Sbjct: 84   LSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-DVDECRVGEPCR-HGGTCLNTPGSF 141

Query: 1027 TCSCHAKWSGEDCSKEV--CS-LECGPHGRC-----VGESCSCAAGWSGEFCSVRLCDA- 1077
             C C A ++G  C      C+   C   G C     +   C+C  G+ G+ C V + D  
Sbjct: 142  RCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCP 201

Query: 1078 --RCAEHGQCKNG----TCLCVSGWNGRHCT--LEGC---PRSCAGHGQCRVDNDGRWEC 1126
              RC   G C +G     C C   W G+ CT  ++ C   P +C   G C  +  G   C
Sbjct: 202  GHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTC-FNTLGGHSC 260

Query: 1127 KCFDGWDGPDCT----TLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSPK 1181
             C +GW G  C+         +C   +  +D+     C  P       C     CVS+P 
Sbjct: 261  VCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPC 320

Query: 1182 PTDILLRKQP 1191
              D +    P
Sbjct: 321  HEDAICDTNP 330



 Score = 97.5 bits (232), Expect = 6e-19
 Identities = 92/313 (29%), Positives = 116/313 (37%), Gaps = 49/313 (15%)

Query: 879  PNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVLCSQRG------EYINGECQCNP 928
            PN C   G C  G     C C PGF G  C++ V   L +  G         +  C C P
Sbjct: 815  PNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPP 874

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPHPTCSGH 982
            G+ G  C     +C    C   G CV+G     C C  GY G  C  E D C    C   
Sbjct: 875  GYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHG 934

Query: 983  GFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
            G C        C C + + G  C T+  D     P C   G        C C   WSG  
Sbjct: 935  GVCSAAHPGFRCTCLESFTGPQCQTL-VDWCSRQP-CQNGGRCVQTGAYCLCPPGWSGRL 992

Query: 1039 CS------KEVCS-----LE--CGPHGRCVGES----CSCAAGWSGEFC--SVRLCDARC 1079
            C       +E  +     LE  C   G+CV E     C C  G +G  C   V  C A+ 
Sbjct: 993  CDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQP 1052

Query: 1080 AEHGQCKNG-----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
             +HG    G      C C+ G+NG +C   ++ C      HG   +D   R+ C C  G 
Sbjct: 1053 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGT 1112

Query: 1133 DGPDCTTLKEQIC 1145
             G  C  + E  C
Sbjct: 1113 LGVLC-EINEDDC 1124



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 89/305 (29%), Positives = 125/305 (40%), Gaps = 53/305 (17%)

Query: 882  CSGKGECLM-----GHCQCQPGFGGDDCS-KSVC-PVLCSQRG----EYING----ECQC 926
            C+  G C         C C PG+ G+ C  +  C    C+ RG      + G     C+C
Sbjct: 9    CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 68

Query: 927  NPGWKGKECSLRHDECEVPDCNGHGHCVNGK-----CSCVRGYKGKFC-GEID-C-PHPT 978
              G++G +CSL  D C    C     C  G      CSC  GY+G+ C  ++D C     
Sbjct: 69   PRGFRGPDCSL-PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 127

Query: 979  CSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVD---TQTCSC 1030
            C   G C+   G+  C C  G+ G  C   +  A+ C P  C   GT       T  C+C
Sbjct: 128  CRHGGTCLNTPGSFRCQCPAGYTGPLC---ENPAVPCAPSPCRNGGTCRQSGDLTYDCAC 184

Query: 1031 HAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR--- 1078
               + G++C   V  C    C   G CV      +C C   W+G+FC+  V  C  +   
Sbjct: 185  LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNA 244

Query: 1079 CAEHGQCKN----GTCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
            C   G C N     +C+CV+GW G  C+  ++ C  +   HG    D    + C C  G 
Sbjct: 245  CHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGK 304

Query: 1133 DGPDC 1137
             G  C
Sbjct: 305  TGLLC 309



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 88/303 (29%), Positives = 118/303 (38%), Gaps = 51/303 (16%)

Query: 882  CSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---------CSQRGEYINGECQCNP 928
            C   G CL       CQC  G+ G  C     P           C Q G+ +  +C C P
Sbjct: 128  CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGD-LTYDCACLP 186

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP-HP-TCS 980
            G++G+ C +  D+C    C   G CV+G     C C   + G+FC E +D C   P  C 
Sbjct: 187  GFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACH 246

Query: 981  GHGFCIE----GTCVCKKGWKGADCGTMDKDALQ--CLPDCSGHGTFDVDTQTCSCHAKW 1034
              G C       +CVC  GW G  C     D     C    + H    V +  C+C    
Sbjct: 247  NGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDR--VASFYCACPMGK 304

Query: 1035 SGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFC--SVRLCD--ARCAEH 1082
            +G  C   + C S  C     C      G + C+C  G++G  C   V  C   A   EH
Sbjct: 305  TGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEH 364

Query: 1083 -GQCKN--GT--CLCVSGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
             G+C N  G+  C C  G+ G  C     E     C     C +D  G++ C C  G+ G
Sbjct: 365  LGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATC-LDRIGQFTCICMAGFTG 423

Query: 1135 PDC 1137
              C
Sbjct: 424  TYC 426



 Score = 83.0 bits (196), Expect = 1e-14
 Identities = 102/361 (28%), Positives = 131/361 (36%), Gaps = 77/361 (21%)

Query: 882  CSGKGECL----MGHCQCQPGFGGDDCSKSVCPVL---CSQRGE---YINGE-CQCNPGW 930
            C   G+C+      +C C  G  G  C + V P L   C   G    Y+ G  C+C PG+
Sbjct: 1015 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY 1074

Query: 931  KGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFC--GEIDC-------PHP 977
             G  C    DEC    C   G C++      CSC  G  G  C   E DC         P
Sbjct: 1075 NGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1134

Query: 978  TCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDTQ-----T 1027
             C  +G C++      C C  G+ G  C   + D  +C    C    T D          
Sbjct: 1135 RCLHNGTCVDLVGGFRCTCPPGYTGLRC---EADINECRSGACHAAHTRDCLQDPGGGFR 1191

Query: 1028 CSCHAKWSGEDCSKEVCSLE---CGPHGRC---------VGESCSCAAGWSGEFCS--VR 1073
            C CHA +SG  C   +   E   C   G+C         +  +C CA  + G  C    R
Sbjct: 1192 CLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVAR 1251

Query: 1074 LC-DARCAEHGQC----KNGTCLCVSGWNGRHC-TLEGCP-----RSCAG----H-GQCR 1117
             C + +C     C    +   C C  G +G  C +  G P      SCA     H G CR
Sbjct: 1252 SCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCR 1311

Query: 1118 -VDNDGRWECKCFDGWDGPDC-------TTLKEQICDDSRDNDKDGLVDCEDPECCQSPA 1169
                   + C C  GW GP C          +E  C  +    K G   C D E C SP 
Sbjct: 1312 PAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRC-DRE-CNSPG 1369

Query: 1170 C 1170
            C
Sbjct: 1370 C 1370



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 28/214 (13%)

Query: 987  EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ------TCSCHAKWSGEDCS 1040
            E  C+C  GW G  C    +D     P C+G G             +C C   + G DCS
Sbjct: 22   EAACLCPPGWVGERCQL--EDPCHSGP-CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCS 78

Query: 1041 -KEVC-SLECGPHGRC-VGES----CSCAAGWSGEFCSVRLCDAR----CAEHGQCKN-- 1087
              + C S  C    RC VG      CSC  G+ G  C   + + R    C   G C N  
Sbjct: 79   LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTP 138

Query: 1088 GT--CLCVSGWNGRHC---TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
            G+  C C +G+ G  C    +   P  C   G CR   D  ++C C  G++G +C    +
Sbjct: 139  GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVD 198

Query: 1143 QICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
              C   R  +    VD  +   CQ P   + Q C
Sbjct: 199  D-CPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 231



 Score = 73.3 bits (172), Expect = 1e-11
 Identities = 86/329 (26%), Positives = 119/329 (36%), Gaps = 71/329 (21%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN----GECQCNPGW 930
            C +G + +G      C+C PG+ GD+C   V  C    C   G  I+      C C PG 
Sbjct: 1053 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGT 1112

Query: 931  KGKECSLRHDEC-------EVPDCNGHGHCVN----GKCSCVRGYKGKFC-GEI-DCPHP 977
             G  C +  D+C         P C  +G CV+     +C+C  GY G  C  +I +C   
Sbjct: 1113 LGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSG 1172

Query: 978  TC-SGH-GFCIEG-----TCVCKKGWKGADCGTM--------DKDALQCLPDCSGHGTFD 1022
             C + H   C++       C+C  G+ G  C T+         +   QC P     G   
Sbjct: 1173 ACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGL- 1231

Query: 1023 VDTQTCSCHAKWSGEDCSKEVCS---LECGPHGRCV----GESCSCAAGWSGEFC----- 1070
              T TC C   + G  C +   S   L+C     C     G  C+C  G SG  C     
Sbjct: 1232 --TFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPG 1289

Query: 1071 ------SVRLCDARCAEHGQCKNG------TCLCVSGWNGRHCTLEGCPRSCAGHGQC-- 1116
                  +     A C   G C+         C C  GW G  C         +   +C  
Sbjct: 1290 SPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPR 1349

Query: 1117 ----RVDNDGRWECKCFD---GWDGPDCT 1138
                    D R + +C     GWDG DC+
Sbjct: 1350 AACQAKRGDQRCDRECNSPGCGWDGGDCS 1378



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 37/109 (33%), Positives = 48/109 (44%), Gaps = 15/109 (13%)

Query: 1079 CAEHGQC-----KNGTCLCVSGWNGRHCTLEGCPRS--CAGHGQCR---VDNDGRWECKC 1128
            CA  G+C     +   CLC  GW G  C LE    S  CAG G C+   V    R+ C+C
Sbjct: 9    CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 68

Query: 1129 FDGWDGPDCT----TLKEQICDDSRDN-DKDGLVDCEDPECCQSPACKS 1172
              G+ GPDC+     L       +R +   DG   C  P   Q  +C+S
Sbjct: 69   PRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS 117



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 58/245 (23%), Positives = 81/245 (33%), Gaps = 31/245 (12%)

Query: 884  GKGECLMGHCQCQPGFGGDDCSKSV-------CPVLCSQRGEYINGECQCNPGWKGKEC- 935
            G G  L   C C   F G  C +         CPV    +       C C PG  G  C 
Sbjct: 1226 GPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCR 1285

Query: 936  -------SLRHDECEVPDCNGHGHCVNG------KCSCVRGYKGKFCGEIDCPHPTCSGH 982
                      +  C    C   G C         +C+C +G+ G  C E     P  S  
Sbjct: 1286 SFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRC-EAPAAAPEVSEE 1344

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
              C    C  K+G +  D    + ++  C  D  G  +  V      C A       +  
Sbjct: 1345 PRCPRAACQAKRGDQRCD---RECNSPGCGWD-GGDCSLSVGDPWRQCEALQCWRLFNNS 1400

Query: 1043 VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH---GQCKNGTCLCVSGWNGR 1099
             C   C     C+ ++  C AG     C+  + +  CA+H   G+C  G      GW+G 
Sbjct: 1401 RCDPACSSPA-CLYDNFDCHAGGRERTCNP-VYEKYCADHFADGRCDQGCNTEECGWDGL 1458

Query: 1100 HCTLE 1104
             C  E
Sbjct: 1459 DCASE 1463



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 78/327 (23%), Positives = 106/327 (32%), Gaps = 69/327 (21%)

Query: 882  CSGKGEC--LMG--HCQCQPGFGG-------DDCSKSVCPVLCSQRGEYING---ECQCN 927
            C   G C  L+G   C C PG+ G       ++C    C    ++      G    C C+
Sbjct: 1136 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCH 1195

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHC---------VNGKCSCVRGYKGKFCGEI--DCPH 976
             G+ G  C      CE   C   G C         +   C C + + G  C  +   C  
Sbjct: 1196 AGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRE 1255

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKD----------ALQCLPDCSGHGTFD 1022
              C     C +      C C  G  G  C +              A  CL   S      
Sbjct: 1256 LQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPL 1315

Query: 1023 VDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESC--------------SCAAGWSGE 1068
                 C+C   W+G  C     + E     RC   +C              S   GW G 
Sbjct: 1316 APFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGG 1375

Query: 1069 FCSVRLCDA-RCAEHGQC----KNGTC--LCVSG---WNGRHCTLEGCPRSC-AGHGQCR 1117
             CS+ + D  R  E  QC     N  C   C S    ++   C   G  R+C   + +  
Sbjct: 1376 DCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYC 1435

Query: 1118 VDN--DGRWECKCFD---GWDGPDCTT 1139
             D+  DGR +  C     GWDG DC +
Sbjct: 1436 ADHFADGRCDQGCNTEECGWDGLDCAS 1462



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 41/162 (25%), Positives = 52/162 (32%), Gaps = 23/162 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C C  G+ G  C         S+        CQ   G   + C     EC  P C   G 
Sbjct: 1321 CACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRG--DQRCDR---ECNSPGCGWDG- 1374

Query: 953  CVNGKCSCVRGYKGKFCGEIDCPH--------PTCSGHGFCIEGTCVCKKGWKGADCGTM 1004
               G CS   G   + C  + C          P CS    C+     C  G +   C  +
Sbjct: 1375 ---GDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPA-CLYDNFDCHAGGRERTCNPV 1430

Query: 1005 DKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSL 1046
             +    C  D    G  D    T  C   W G DC+ EV +L
Sbjct: 1431 YEK--YCA-DHFADGRCDQGCNTEECG--WDGLDCASEVPAL 1467


>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
          Length = 1218

 Score =  120 bits (289), Expect = 8e-26
 Identities = 89/293 (30%), Positives = 118/293 (40%), Gaps = 37/293 (12%)

Query: 878  CPNGCSGK-GEC-LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKEC 935
            C  GCS K G C L G C+CQ G+ G  C K +    C         +C C   W G+ C
Sbjct: 234  CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLC 293

Query: 936  SLRHDECEV-PDCNGHGHCVNG-----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE 987
                + C     C   G C N      +CSC  GY G  C   E  C    C   G C E
Sbjct: 294  DKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKE 353

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS 1040
             +    C C  GW G  C T   D   C P +CS  GT    V+   C C  +W+G+ C 
Sbjct: 354  TSLGFECECSPGWTGPTCSTNIDD---CSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQ 410

Query: 1041 KEVCSLECGP-------HGRCVGESCSCAAGWSGEFCSVRL--CDARCAEHGQCK---NG 1088
             +    E  P               C C  GW G+ C + +  C  +C     C+   NG
Sbjct: 411  LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNG 470

Query: 1089 -TCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+C  G+ G HC   ++ C  + C   G C+ +   R++C C  G+ G  C
Sbjct: 471  YRCICPPGYAGDHCERDIDECASNPCLDGGHCQ-NEINRFQCLCPTGFSGNLC 522



 Score =  119 bits (287), Expect = 1e-25
 Identities = 100/333 (30%), Positives = 129/333 (38%), Gaps = 68/333 (20%)

Query: 870  VAEEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYINGE--- 923
            + E  ++ C +G   + E     C C  GF G+ C   +  C P  C    +  N     
Sbjct: 488  IDECASNPCLDGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDY 547

Query: 924  -CQCNPGWKGKECS-----LRHDECEVPD----------------------CNGHGHCVN 955
             C+C   ++GK CS      R   CEV D                      C  HG C +
Sbjct: 548  FCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKS 607

Query: 956  ---GK--CSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTM 1004
               GK  C C +G+ G +C E   DC    C   G CI+G     C+C  GW+GA C T 
Sbjct: 608  QSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN 667

Query: 1005 DKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGEDC---SKEVCSLECGPHGRCVGE-- 1057
              D  Q    C   GT    V+   C C   W G+ C     +     C   G C  E  
Sbjct: 668  INDCSQ--NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD 725

Query: 1058 --SCSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNG---TCLCVSGWNGRHC---TLE 1104
               C C  GW G  C++    +     C   G C  NG   TC+C  GW G  C   T +
Sbjct: 726  AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND 785

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              P  C   G C VD D  + C+C  G+ GPDC
Sbjct: 786  CSPHPCYNSGTC-VDGDNWYRCECAPGFAGPDC 817



 Score =  116 bits (280), Expect = 1e-24
 Identities = 86/270 (31%), Positives = 115/270 (42%), Gaps = 36/270 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + G  C+K  C       G Y    NG   C  GW G+EC+     C       HG
Sbjct: 187  CDDYYYGFGCNK-FCRPRDDFFGHYACDQNGNKTCMEGWMGRECN--RAICRQGCSPKHG 243

Query: 952  HC-VNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL 1009
             C + G C C  G++G +C +   PHP C  HG C E   C+C+  W G  C   DKD  
Sbjct: 244  SCKLPGDCRCQYGWQGLYCDKC-IPHPGCV-HGICNEPWQCLCETNWGGQLC---DKDLN 298

Query: 1010 QC--LPDCSGHGTFD---VDTQTCSCHAKWSGEDC--SKEVC-SLECGPHGRC----VGE 1057
             C     C   GT      D   CSC   +SG +C  ++  C S  C   G C    +G 
Sbjct: 299  YCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGF 358

Query: 1058 SCSCAAGWSGEFCSVRLCDA---RCAEHGQCK---NG-TCLCVSGWNGRHCTLEG--C-P 1107
             C C+ GW+G  CS  + D     C+  G C+   NG  C+C   W G+ C L+   C  
Sbjct: 359  ECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            + C     C+ +    + C C  GW G +C
Sbjct: 419  KPCVNAKSCK-NLIASYYCDCLPGWMGQNC 447



 Score =  113 bits (273), Expect = 7e-24
 Identities = 85/291 (29%), Positives = 108/291 (37%), Gaps = 36/291 (12%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C CN G+ G  C    ++CE   C   G C++G    KC C  G++G +C     DC   
Sbjct: 615  CDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN 674

Query: 978  TCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGT-FDV-DTQTCSCH 1031
             C   G C +      C CK GWKG  C + D    +    C+  GT +D  D   C C 
Sbjct: 675  PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA--TCNNGGTCYDEGDAFKCMCP 732

Query: 1032 AKWSGEDC----SKEVCSLECGPHGRCV--GES--CSCAAGWSGEFCSVRLCDAR---CA 1080
              W G  C    +       C   G CV  GES  C C  GW G  C+    D     C 
Sbjct: 733  GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCY 792

Query: 1081 EHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
              G C +G     C C  G+ G  C   +  C  S    G   VD    + C C  G  G
Sbjct: 793  NSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSG 852

Query: 1135 PDCTTLKEQICDDSRDNDKDGLV---DCEDPECCQSPACKSSQLCVSSPKP 1182
              C  +  + C        DG     DC   +C       S   C   P+P
Sbjct: 853  AKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWC--GPRP 901



 Score =  107 bits (257), Expect = 6e-22
 Identities = 79/287 (27%), Positives = 120/287 (41%), Gaps = 40/287 (13%)

Query: 893  CQCQPGFGGDDCSKSV--C----PVL----CSQRGEYINGECQCNPGWKGKECSLRHDEC 942
            C C+  +GG  C K +  C    P L    CS  G     +C C  G+ G  C +    C
Sbjct: 282  CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPD-KYQCSCPEGYSGPNCEIAEHAC 340

Query: 943  EVPDCNGHGHC----VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFC---IEG-TCVC 992
                C+  G C    +  +C C  G+ G  C     DC    CS  G C   + G  CVC
Sbjct: 341  LSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVC 400

Query: 993  KKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSGEDCSKEV--CSLECG 1049
               W G  C  +D +  +  P  +     + + +  C C   W G++C   +  C  +C 
Sbjct: 401  PPQWTGKTC-QLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQ 459

Query: 1050 PHGRCV----GESCSCAAGWSGEFCS--VRLCDAR-CAEHGQCKNGT----CLCVSGWNG 1098
                C     G  C C  G++G+ C   +  C +  C + G C+N      CLC +G++G
Sbjct: 460  NDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLDGGHCQNEINRFQCLCPTGFSG 519

Query: 1099 RHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
              C L+   C P  C    QC  +    + CKC + ++G +C+ LK+
Sbjct: 520  NLCQLDIDYCEPNPCQNGAQC-YNRASDYFCKCPEDYEGKNCSHLKD 565



 Score =  105 bits (251), Expect = 3e-21
 Identities = 90/317 (28%), Positives = 132/317 (41%), Gaps = 50/317 (15%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCS-QRGE-YINGECQCNPGWKGKECSLRHDEC-EVPDC 947
            G+  C  G+ G +C++++C   CS + G   + G+C+C  GW+G  C    D+C   P C
Sbjct: 216  GNKTCMEGWMGRECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYC----DKCIPHPGC 271

Query: 948  NGHGHCVN-GKCSCVRGYKGKFCG-EID-C-PHPTCSGHGFCI-----EGTCVCKKGWKG 998
              HG C    +C C   + G+ C  +++ C  H  C   G C      +  C C +G+ G
Sbjct: 272  -VHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSG 330

Query: 999  ADCGTMDKDALQCLPD-CSGHGTFDVDTQ--TCSCHAKWSGEDCSKEV--CS-LECGPHG 1052
             +C   +     CL D C   G+    +    C C   W+G  CS  +  CS   C   G
Sbjct: 331  PNCEIAEH---ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387

Query: 1053 RCV----GESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKN----GTCLCVSGWNGRHC 1101
             C     G  C C   W+G+ C +    C+A+ C     CKN      C C+ GW G++C
Sbjct: 388  TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNC 447

Query: 1102 --TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDC 1159
               +  C   C     CR D    + C C  G+ G  C           RD D+     C
Sbjct: 448  DININDCLGQCQNDASCR-DLVNGYRCICPPGYAGDHC----------ERDIDECASNPC 496

Query: 1160 EDPECCQSPACKSSQLC 1176
             D   CQ+   +   LC
Sbjct: 497  LDGGHCQNEINRFQCLC 513



 Score =  104 bits (250), Expect = 4e-21
 Identities = 80/263 (30%), Positives = 107/263 (40%), Gaps = 38/263 (14%)

Query: 875  THN-CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGEY----INGEC 924
            TH  C NG  CS  G      C C  G+ G +C  +    L   C  RG      +  EC
Sbjct: 302  THQPCLNGGTCSNTGPDKY-QCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFEC 360

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPT 978
            +C+PGW G  CS   D+C   +C+  G C   VNG KC C   + GK C     +C    
Sbjct: 361  ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP 420

Query: 979  CSGHGFC----IEGTCVCKKGWKGADCGTMDKDAL-QCLPDCSGHGTFDVDTQTCSCHAK 1033
            C     C        C C  GW G +C     D L QC  D S      V+   C C   
Sbjct: 421  CVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDL--VNGYRCICPPG 478

Query: 1034 WSGEDCSKEV---CSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHG 1083
            ++G+ C +++    S  C   G C  E     C C  G+SG  C + +  C+   C    
Sbjct: 479  YAGDHCERDIDECASNPCLDGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGA 538

Query: 1084 QCKNGT----CLCVSGWNGRHCT 1102
            QC N      C C   + G++C+
Sbjct: 539  QCYNRASDYFCKCPEDYEGKNCS 561



 Score =  101 bits (242), Expect = 4e-20
 Identities = 93/295 (31%), Positives = 116/295 (39%), Gaps = 48/295 (16%)

Query: 866  FVALVAEEMTHNCP-NGCSGKGECLMG----HCQCQPGFGG-------DDCSKSVCPVLC 913
            F      E  ++C  N C   G C+ G     C C  G+ G       +DCS++ C    
Sbjct: 621  FTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGG 680

Query: 914  SQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC 969
            + R    +  C C  GWKGK C  R  +C+   CN  G C +     KC C  G++G  C
Sbjct: 681  TCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTC 740

Query: 970  G---EIDC-PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLP-DCSGHGT 1020
                   C P+P C   G C+      TCVCK+GW+G  C     D   C P  C   GT
Sbjct: 741  NIARNSSCLPNP-CHNGGTCVVNGESFTCVCKEGWEGPICAQNTND---CSPHPCYNSGT 796

Query: 1021 -FDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPHGRCV----GESCSCAAGWSGEFC- 1070
              D D    C C   ++G DC     E  S  C     CV    G  C C  G SG  C 
Sbjct: 797  CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856

Query: 1071 --SVRLC--DARCAEHGQCKNGTCLCVSGWNGR-HCTLEGC-PRSC---AGHGQC 1116
              S R C         G   +  C      NGR  C+   C PR C    GH +C
Sbjct: 857  EVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSEC 911



 Score = 83.0 bits (196), Expect = 1e-14
 Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 16/177 (9%)

Query: 1011 CLP--DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP-HGRC-VGESCSCAAGWS 1066
            C P  D  GH   D +    +C   W G +C++ +C   C P HG C +   C C  GW 
Sbjct: 200  CRPRDDFFGHYACDQNGNK-TCMEGWMGRECNRAICRQGCSPKHGSCKLPGDCRCQYGWQ 258

Query: 1067 GEFCSVRLCDARCAEHGQCKNG-TCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDND 1121
            G +C   +    C  HG C     CLC + W G+ C  +    G  + C   G C     
Sbjct: 259  GLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGP 317

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDD---SRDNDKDGLV--DCEDPECCQSPACKSS 1173
             +++C C +G+ GP+C   +     D   +R + K+  +  +CE       P C ++
Sbjct: 318  DKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTN 374


>BC020198-1|AAH20198.1|  567|Homo sapiens MEGF10 protein protein.
          Length = 567

 Score =  119 bits (287), Expect = 1e-25
 Identities = 100/337 (29%), Positives = 138/337 (40%), Gaps = 77/337 (22%)

Query: 877  NCPNGCSGKGECLMGH-CQCQPGFGGDDCSKSV--------CPVLCS-QRGEYIN---GE 923
            +C + C   G C+  + CQC+PG+GG +CS +         C   C  + G   N   G 
Sbjct: 108  HCADKCV-HGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGA 166

Query: 924  CQCNPGWKGKECSLRHDECEVP-DCNGHGHCVNG--------KCSCVRGYKGKFCGEIDC 974
            C C  G++G  C  R ++     DC+    C NG        +C C  GY G FC ++ C
Sbjct: 167  CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDL-C 225

Query: 975  P----------HPTCSGHGFC--IEGTCVCKKGWKGADCGTMDKDAL---QCLPDCSGH- 1018
            P             C   G C  + G C C  GW G  CG    +      C  +C  H 
Sbjct: 226  PPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHN 285

Query: 1019 -GTFDVDTQTCSCHAKWSGEDCSKE--------VCS--LECGPHGRC--VGESCSCAAGW 1065
             GT D  T  C C   ++GE C  E        +C+   +C   G+C  V  +C C AG+
Sbjct: 286  GGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGF 345

Query: 1066 SGEFCSVRL---------CDARCAEH----GQC--KNGTCLCVSGWNGRHCTL------- 1103
            +GE C  RL         CD RC  H      C   +G C C  GW+G +C         
Sbjct: 346  AGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFY 405

Query: 1104 -EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
             E C + C+       D+    +C C  G+ G DC+T
Sbjct: 406  GEACQQICSCQNGADCDS-VTGKCTCAPGFKGIDCST 441



 Score =  104 bits (249), Expect = 6e-21
 Identities = 101/334 (30%), Positives = 125/334 (37%), Gaps = 83/334 (24%)

Query: 878  CPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSVCPV-----LCSQRGEYING-------- 922
            CP  C   G C  + G C C  G+ G  C +  CP       CSQ  +  NG        
Sbjct: 238  CP--CQNGGVCHHVTGECSCPSGWMGTVCGQP-CPEGRFGKNCSQECQCHNGGTCDAATG 294

Query: 923  ECQCNPGWKGKECSLRHDEC----------EVPDCNGHGHC--VNGKCSCVRGYKGKFCG 970
            +C C+PG+ G+ C    DEC          E   C   G C  V+G C C  G+ G+ C 
Sbjct: 295  QCHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCE 351

Query: 971  EIDCPH--------PTCSGH----GFC--IEGTCVCKKGWKGADCGTMDKDALQ---CLP 1013
               CP           C  H      C  + G C CK GW G  C            C  
Sbjct: 352  ARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQ 411

Query: 1014 DCSGHGTFDVDTQT--CSCHAKWSGEDCSKEV--------CSLECGPHGRCVGE----SC 1059
             CS     D D+ T  C+C   + G DCS           CS  CG     V      SC
Sbjct: 412  ICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSC 471

Query: 1060 SCAAGWSGEFCSVRL--------CD--ARCAEHGQCK--NGTCLCVSGWNGRHCTL---E 1104
            +C AGW G  CS+R         C+   +C   G C   +GTC C  GW G  C L   +
Sbjct: 472  TCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQD 531

Query: 1105 GC-PRSCAGHGQC-RVD--NDGRWECKCFDGWDG 1134
            G    +CA    C   D  +     C+C  GW G
Sbjct: 532  GTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSG 565



 Score =   99 bits (238), Expect = 1e-19
 Identities = 80/262 (30%), Positives = 107/262 (40%), Gaps = 57/262 (21%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP-----VLCSQRGEY---------- 919
            T  C NG  GK   + G C C+ GF G+ C   +CP     + C +R             
Sbjct: 323  TCQCVNG--GKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHP 380

Query: 920  INGECQCNPGWKGKECS------LRHDECE-VPDCNGHGHC--VNGKCSCVRGYKGKFCG 970
            ++GEC C PGW G  C+         + C+ +  C     C  V GKC+C  G+KG  C 
Sbjct: 381  MSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCS 440

Query: 971  EIDCPHPT----------CSGHGFC--IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGH 1018
               CP  T          C     C  ++G+C CK GW G DC      +++C     G 
Sbjct: 441  T-PCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC------SIRCPSGTWGF 493

Query: 1019 GTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCS--CAAGWSGEFCSVRLCD 1076
            G       TC C    +G  C+    +  C P  R  GE C   C  G  G  C+ R CD
Sbjct: 494  GC----NLTCQC---LNGGACNTLDGTCTCAPGWR--GEKCELPCQDGTYGLNCAER-CD 543

Query: 1077 ARCAEHGQCKNGTCLCVSGWNG 1098
               A+      G C C+ GW+G
Sbjct: 544  CSHADGCHPTTGHCRCLPGWSG 565



 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 86/310 (27%), Positives = 120/310 (38%), Gaps = 72/310 (23%)

Query: 894  QCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL-----RHD-ECEVP-D 946
            +C+ G  G+DC +  C        +++ GEC+C PG+ G  C       +H  +CE    
Sbjct: 181  RCEQGTYGNDCHQR-CQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCP 239

Query: 947  CNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHPT----------CSGHGFC--IEGTCVC 992
            C   G C  V G+CSC  G+ G  CG+  CP             C   G C    G C C
Sbjct: 240  CQNGGVCHHVTGECSCPSGWMGTVCGQ-PCPEGRFGKNCSQECQCHNGGTCDAATGQCHC 298

Query: 993  KKGWKGADC---------GTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV 1043
              G+ G  C         G +  +  QC+   +G   + V +  C C A ++GE C   +
Sbjct: 299  SPGYTGERCQDECPVGTYGVLCAETCQCV---NGGKCYHV-SGACLCEAGFAGERCEARL 354

Query: 1044 C-----SLECGPHGRCVGES----------CSCAAGWSG----EFCSVRLCDARCAEHGQ 1084
            C      ++C     C  E+          C+C  GWSG    E CS       C +   
Sbjct: 355  CPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICS 414

Query: 1085 CKNGT--------CLCVSGWNGRHCTLEGCPRSCAG---HGQCRVDNDG-----RWECKC 1128
            C+NG         C C  G+ G  C+   CP    G     +C   ND         C C
Sbjct: 415  CQNGADCDSVTGKCTCAPGFKGIDCSTP-CPLGTYGINCSSRCGCKNDAVCSPVDGSCTC 473

Query: 1129 FDGWDGPDCT 1138
              GW G DC+
Sbjct: 474  KAGWHGVDCS 483


>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
            protein.
          Length = 1140

 Score =  119 bits (287), Expect = 1e-25
 Identities = 100/337 (29%), Positives = 138/337 (40%), Gaps = 77/337 (22%)

Query: 877  NCPNGCSGKGECLMGH-CQCQPGFGGDDCSKSV--------CPVLCS-QRGEYIN---GE 923
            +C + C   G C+  + CQC+PG+GG +CS +         C   C  + G   N   G 
Sbjct: 108  HCADKCV-HGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGA 166

Query: 924  CQCNPGWKGKECSLRHDECEVP-DCNGHGHCVNG--------KCSCVRGYKGKFCGEIDC 974
            C C  G++G  C  R ++     DC+    C NG        +C C  GY G FC ++ C
Sbjct: 167  CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDL-C 225

Query: 975  P----------HPTCSGHGFC--IEGTCVCKKGWKGADCGTMDKDAL---QCLPDCSGH- 1018
            P             C   G C  + G C C  GW G  CG    +      C  +C  H 
Sbjct: 226  PPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHN 285

Query: 1019 -GTFDVDTQTCSCHAKWSGEDCSKE--------VCS--LECGPHGRC--VGESCSCAAGW 1065
             GT D  T  C C   ++GE C  E        +C+   +C   G+C  V  +C C AG+
Sbjct: 286  GGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGF 345

Query: 1066 SGEFCSVRL---------CDARCAEH----GQC--KNGTCLCVSGWNGRHCTL------- 1103
            +GE C  RL         CD RC  H      C   +G C C  GW+G +C         
Sbjct: 346  AGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFY 405

Query: 1104 -EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
             E C + C+       D+    +C C  G+ G DC+T
Sbjct: 406  GEACQQICSCQNGADCDS-VTGKCTCAPGFKGIDCST 441



 Score =  108 bits (259), Expect = 3e-22
 Identities = 102/333 (30%), Positives = 133/333 (39%), Gaps = 72/333 (21%)

Query: 873  EMTHNCPNGCSGKGECLMG----HCQ--CQPGFGGDDCSKSVCPVLCSQRGEYINGECQC 926
            E TH+C +  SG+  C  G    +C   C PGF G+ C + +C        + + G+C C
Sbjct: 373  ENTHSC-HPMSGECACKPGWSGLYCNETCSPGFYGEACQQ-ICSCQNGADCDSVTGKCTC 430

Query: 927  NPGWKGKECSLRHD------ECEVP-DCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHP 977
             PG+KG +CS           C     C     C  V+G C+C  G+ G  C  I CP  
Sbjct: 431  APGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCS-IRCPSG 489

Query: 978  T----------CSGHGFC--IEGTCVCKKGWKGADCGTMDKDA---LQCLP--DCSGHGT 1020
            T          C   G C  ++GTC C  GW+G  C    +D    L C    DCS    
Sbjct: 490  TWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADG 549

Query: 1021 FDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGR--CV---GESCS-------CAAGWSGE 1068
                T  C C   WSG  C         GP+    C    G SCS       CA G+ G 
Sbjct: 550  CHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGT 609

Query: 1069 FCSVRLCDA-----RCAE--------HGQCKN--GTCLCVSGWNGRHCTLEGCPRSCAGH 1113
             C  R+C       RC++         G C +  G C C+ G+ G  C  E CP    G 
Sbjct: 610  TCQ-RICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCN-EVCPSGRFGK 667

Query: 1114 ---GQCRVDNDGRWE-----CKCFDGWDGPDCT 1138
               G C   N+G        C+C+ GW G DC+
Sbjct: 668  NCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCS 700



 Score =  107 bits (257), Expect = 6e-22
 Identities = 105/350 (30%), Positives = 131/350 (37%), Gaps = 89/350 (25%)

Query: 878  CPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSVCPV-----LCSQRGEYING-------- 922
            CP  C   G C  + G C C  G+ G  C +  CP       CSQ  +  NG        
Sbjct: 238  CP--CQNGGVCHHVTGECSCPSGWMGTVCGQP-CPEGRFGKNCSQECQCHNGGTCDAATG 294

Query: 923  ECQCNPGWKGKECSLRHDEC----------EVPDCNGHGHC--VNGKCSCVRGYKGKFCG 970
            +C C+PG+ G+ C    DEC          E   C   G C  V+G C C  G+ G+ C 
Sbjct: 295  QCHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCE 351

Query: 971  EIDCPH--------PTCSGH----GFC--IEGTCVCKKGWKGADCGTMDKDALQ---CLP 1013
               CP           C  H      C  + G C CK GW G  C            C  
Sbjct: 352  ARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQ 411

Query: 1014 DCSGHGTFDVDTQT--CSCHAKWSGEDCSKEV--------CSLECGPHGRCVGE----SC 1059
             CS     D D+ T  C+C   + G DCS           CS  CG     V      SC
Sbjct: 412  ICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSC 471

Query: 1060 SCAAGWSGEFCSVRL--------CD--ARCAEHGQCK--NGTCLCVSGWNGRHCTL---E 1104
            +C AGW G  CS+R         C+   +C   G C   +GTC C  GW G  C L   +
Sbjct: 472  TCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQD 531

Query: 1105 GC-PRSCAGHGQCRVDNDG----RWECKCFDGWDGPDCTTLKEQICDDSR 1149
            G    +CA    C    DG       C+C  GW G  C    + +C + R
Sbjct: 532  GTYGLNCAERCDCS-HADGCHPTTGHCRCLPGWSGVHC----DSVCAEGR 576



 Score =  107 bits (256), Expect = 8e-22
 Identities = 97/335 (28%), Positives = 131/335 (39%), Gaps = 81/335 (24%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP-----VLCSQRGEYIN--------GEC 924
            C NG  G  +   G C C PG+ G+ C +  CP     VLC++  + +N        G C
Sbjct: 283  CHNG--GTCDAATGQCHCSPGYTGERC-QDECPVGTYGVLCAETCQCVNGGKCYHVSGAC 339

Query: 925  QCNPGWKGKECSLR-----------HDECEVPDCNGHG-HCVNGKCSCVRGYKGKFCGEI 972
             C  G+ G+ C  R              C     N H  H ++G+C+C  G+ G +C E 
Sbjct: 340  LCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNET 399

Query: 973  DCPH---------PTCSGHGFC--IEGTCVCKKGWKGADCGT---MDKDALQCLP--DCS 1016
              P           +C     C  + G C C  G+KG DC T   +    + C     C 
Sbjct: 400  CSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCK 459

Query: 1017 GHGTFDVDTQTCSCHAKWSGEDCSKEV--------CSL--ECGPHGRC--VGESCSCAAG 1064
                      +C+C A W G DCS           C+L  +C   G C  +  +C+CA G
Sbjct: 460  NDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPG 519

Query: 1065 WSGEFCSVRLCDA----RCAEHGQCKN--------GTCLCVSGWNGRHC---TLEG---- 1105
            W GE C +   D      CAE   C +        G C C+ GW+G HC     EG    
Sbjct: 520  WRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGP 579

Query: 1106 -C--PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C  P  C     C  D DG   C+C  G+ G  C
Sbjct: 580  NCSLPCYCKNGASCSPD-DG--ICECAPGFRGTTC 611



 Score =  103 bits (246), Expect = 1e-20
 Identities = 94/335 (28%), Positives = 132/335 (39%), Gaps = 74/335 (22%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCS----KSVCPVLCSQRGEYIN-------- 921
            +T  C NG  G    L G C C PG+ G+ C          + C++R +  +        
Sbjct: 497  LTCQCLNG--GACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTT 554

Query: 922  GECQCNPGWKGKEC-SLRHDECEVPDCNGHGHCVNGK--------CSCVRGYKGKFCGEI 972
            G C+C PGW G  C S+  +    P+C+   +C NG         C C  G++G  C  I
Sbjct: 555  GHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRI 614

Query: 973  DCP----H------PTC---SGHGFCIEGTCVCKKGWKGADCGTM---DKDALQC--LPD 1014
              P    H      P C   SG    I G C C  G+ GA C  +    +    C  +  
Sbjct: 615  CSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICT 674

Query: 1015 CSGHGTFDVDTQTCSCHAKWSGEDCSK------------EVCSLECGPHGRCVGESCSCA 1062
            C+ +GT +   ++C C+  W G DCS+              C+   G         C C 
Sbjct: 675  CTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCT 734

Query: 1063 AGWSGEFCSVR----LCDARCAEHGQCKNGT--------CLCVSGWNGRHCTLEGCPRSC 1110
             GW+G +C+ R         CA   QC+NG         C C +G+ GRHC  + CP   
Sbjct: 735  PGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCE-QKCPSGT 793

Query: 1111 AGHG---QCRVDNDGRWE-----CKCFDGWDGPDC 1137
             G+G    C   N+   +     C C  GW G  C
Sbjct: 794  YGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARC 828



 Score = 92.7 bits (220), Expect = 2e-17
 Identities = 94/336 (27%), Positives = 126/336 (37%), Gaps = 80/336 (23%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP-----VLCSQRG--------EYINGE 923
            +C NG     + + G C C PGF G DCS + CP     + CS R           ++G 
Sbjct: 414  SCQNGADC--DSVTGKCTCAPGFKGIDCS-TPCPLGTYGINCSSRCGCKNDAVCSPVDGS 470

Query: 924  CQCNPGWKGKECSLRHDE------CEVP-DCNGHGHC--VNGKCSCVRGYKGKFCGEIDC 974
            C C  GW G +CS+R         C +   C   G C  ++G C+C  G++G+ C E+ C
Sbjct: 471  CTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKC-ELPC 529

Query: 975  PHPT----------CSGHGFC--IEGTCVCKKGWKGADCGTMDKDAL---QC-LPD-CSG 1017
               T          CS    C    G C C  GW G  C ++  +      C LP  C  
Sbjct: 530  QDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKN 589

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSK--------EVCSLEC-------GPHGRCVGESCSCA 1062
              +   D   C C   + G  C +          CS  C       GP     G  C C 
Sbjct: 590  GASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITG-LCDCL 648

Query: 1063 AGWSGEFCSVRLCDAR----------CAEHGQCK--NGTCLCVSGWNGRHCTLEGCPRSC 1110
             G++G  C+      R          C  +G C   + +C C  GW G  C+ + CP + 
Sbjct: 649  PGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCS-QPCPPAH 707

Query: 1111 AGHG---QCRVDNDG-----RWECKCFDGWDGPDCT 1138
             G      C   N         ECKC  GW G  CT
Sbjct: 708  WGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCT 743



 Score = 91.9 bits (218), Expect = 3e-17
 Identities = 82/293 (27%), Positives = 112/293 (38%), Gaps = 73/293 (24%)

Query: 882  CSGKGEC--LMGHCQCQPGFGGDDCSKSVC-----------PVLCSQRGEYI--NGECQC 926
            CS    C    GHC+C PG+ G  C  SVC           P  C         +G C+C
Sbjct: 544  CSHADGCHPTTGHCRCLPGWSGVHCD-SVCAEGRWGPNCSLPCYCKNGASCSPDDGICEC 602

Query: 927  NPGWKGKECS------LRHDECE--VPDC---NGHGHCVNGKCSCVRGYKGKFCGEIDCP 975
             PG++G  C            C    P C   +G  H + G C C+ G+ G  C E+ CP
Sbjct: 603  APGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEV-CP 661

Query: 976  HP----------TCSGHGFC--IEGTCVCKKGWKGADCGTMDKDAL---QCLPDCSGH-G 1019
                        TC+ +G C  I+ +C C  GW G+DC      A     C+  C+ H G
Sbjct: 662  SGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNG 721

Query: 1020 TF-DVDTQTCSCHAKWSGEDCSKEV--------CSL--ECGPHGRC--VGESCSCAAGWS 1066
             F       C C   W+G  C++          C+L  +C     C  +   C+C  G+ 
Sbjct: 722  AFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFM 781

Query: 1067 GEFCSVR------------LCDARCAEHGQCKN--GTCLCVSGWNGRHCTLEG 1105
            G  C  +            +CD  C  +  C +  GTC C  GW G  C   G
Sbjct: 782  GRHCEQKCPSGTYGYGCRQICD--CLNNSTCDHITGTCYCSPGWKGARCDQAG 832



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 63/221 (28%), Positives = 81/221 (36%), Gaps = 43/221 (19%)

Query: 862  QEISFVALVAEEMTHNCPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSVCP--------- 910
            Q I          +  CP      G C  + G C C PGF G  C++ VCP         
Sbjct: 612  QRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNE-VCPSGRFGKNCA 670

Query: 911  --VLCSQRGEY--INGECQCNPGWKGKECSLRHDECE-----VPDCNGHG----HCVNGK 957
                C+  G    I+  CQC PGW G +CS            +  CN H        +G+
Sbjct: 671  GICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE 730

Query: 958  CSCVRGYKGKFCGEI--------DCPHPT-CSGHGFC--IEGTCVCKKGWKGADC----- 1001
            C C  G+ G +C +         DC     C     C  I G C C+ G+ G  C     
Sbjct: 731  CKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCP 790

Query: 1002 -GTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
             GT      Q + DC  + T D  T TC C   W G  C +
Sbjct: 791  SGTYGYGCRQ-ICDCLNNSTCDHITGTCYCSPGWKGARCDQ 830


>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
          Length = 2003

 Score =  118 bits (284), Expect = 3e-25
 Identities = 100/345 (28%), Positives = 139/345 (40%), Gaps = 45/345 (13%)

Query: 874  MTHNCPNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---CSQRGEYIN----G 922
            M    P+ C   G CL      +C C PG+ G  C       L   C      ++     
Sbjct: 438  MAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATF 497

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGE-ID-CPH 976
             C C PG +G+ C +  +EC    C  H  C   +NG +C C+ G+ G  C E ID C  
Sbjct: 498  HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 557

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CS 1029
              C+  G C +      C C  G++G  C T   +  +CL D    G   +D      C 
Sbjct: 558  SPCANGGQCQDQPGAFHCKCLPGFEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCL 614

Query: 1030 CHAKWSGEDCSKEVCSLE-CGPHGRCVGE----SCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            C + ++G+ C   +C+   C P   C  +    +C C  G  G  C+    +  C  HG 
Sbjct: 615  CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGH 671

Query: 1085 CKNGTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC---- 1137
            C+  +C+C  GW G  C  E  GC    CA  G C     G + C C  G+ GP C    
Sbjct: 672  CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEM 730

Query: 1138 TTLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACK-SSQLCVSSP 1180
            T      C +    N   G   C  P     P C+ S+  CVS+P
Sbjct: 731  TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 775



 Score =  114 bits (275), Expect = 4e-24
 Identities = 100/349 (28%), Positives = 136/349 (38%), Gaps = 51/349 (14%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C----PVLCSQRGEYING----E 923
            ++H C NG + +       C C   + G DCS+ V  C    P  C   G   N      
Sbjct: 281  VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID-CPHPT 978
            C C  GW G  C    D+C    C     C++      C C  G  G  C   D C    
Sbjct: 341  CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 400

Query: 979  CSGHGFC----IEGT--CVCKKGWKGADCGTMDKDALQCL-----PDCSGHGTFDVDTQ- 1026
            C G   C    + G+  C+C+ G+ G  C    +D  +CL     P    HG   ++T  
Sbjct: 401  CHGDAQCSTNPLTGSTLCLCQPGYSGPTC---HQDLDECLMAQQGPSPCEHGGSCLNTPG 457

Query: 1027 --TCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--- 1074
               C C   ++G  C     E  S  C P   C+       C C  G  G+ C V     
Sbjct: 458  SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517

Query: 1075 CDARCAEHGQCK---NG-TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECK 1127
              A C  H  C    NG  C+C+ G++G  C   ++ C  S CA  GQC+ D  G + CK
Sbjct: 518  ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ-DQPGAFHCK 576

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
            C  G++GP C T  ++   D        L D      C  P+  + QLC
Sbjct: 577  CLPGFEGPRCQTEVDECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLC 624



 Score =  105 bits (253), Expect = 2e-21
 Identities = 91/292 (31%), Positives = 120/292 (41%), Gaps = 51/292 (17%)

Query: 893  CQCQPGFGGDDCSKSV---CPV-LCSQRGE-YING----ECQCNPGWKGKECSLRHDECE 943
            C C PGF G+ C   +   CP   CS+RG  +I      +C C PGW G++C LR D C 
Sbjct: 103  CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCS 161

Query: 944  VPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDC---PHPTCSG---HGFCIEGTCV 991
               C   G C+      +C C  G++G  C     +C   P P   G   H       C+
Sbjct: 162  ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 221

Query: 992  CKKGWKGADCGTMDKDALQCLP-DCSGHGTF------DVDTQTCSCHAKWSGEDC--SKE 1042
            C  G +G  C   +  A  C P  CS  GT       D     C C   + G DC  + +
Sbjct: 222  CPVGQEGPRC---ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278

Query: 1043 VC-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR----CAEHGQCKNGT-- 1089
             C S +C   G C       +C C   W+G  CS  V  C+ +    C   G C+N    
Sbjct: 279  NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338

Query: 1090 --CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+CVSGW G  C   L+ C  +    G   +D  G + C C  G  G  C
Sbjct: 339  FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 96/357 (26%), Positives = 138/357 (38%), Gaps = 55/357 (15%)

Query: 870  VAEEMTHNCPNG-CSGKGEC---LMG-HCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN 921
            + E  T+ C +  C    +C   L G  C C PGF G  C + +  C    C+  G+  +
Sbjct: 509  LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD 568

Query: 922  G----ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCGEID 973
                  C+C PG++G  C    DEC    C     C++  G   C C  G+ G+ C    
Sbjct: 569  QPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL 628

Query: 974  CPHPTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            C    C     C +      C+C  G  G  C   + D   C      HG       +C 
Sbjct: 629  CAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPE-DNCTC-----HHG--HCQRSSCV 678

Query: 1030 CHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-C 1079
            C   W+G +C  E+  C S  C   G C     G +C+C  G++G  CS  +  C +  C
Sbjct: 679  CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC 738

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGW 1132
               G C        C C     G  C  + + C  + C   G C V+  G + C C  G+
Sbjct: 739  LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC-VNRPGTFSCLCAMGF 797

Query: 1133 DGPDCTTLKEQICDDSRDNDKDGLVDC-EDPEC-CQS----PACKS-SQLCVSSPKP 1182
             GP C       C DS   ++    D  + P C C +     +C++   LC   P P
Sbjct: 798  QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCP 854



 Score = 89.0 bits (211), Expect = 2e-16
 Identities = 81/295 (27%), Positives = 115/295 (38%), Gaps = 54/295 (18%)

Query: 892  HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGE----------CQCNPGWKGKECSLRHDE 941
            +C C  G+ G  CS+ +    C   G  +NG           C C P   G +C    D 
Sbjct: 714  NCTCPTGYTGPTCSEEM--TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDY 770

Query: 942  CEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI--DCPHPTCSGHGFCIEG----TC 990
            C    C   G CVN      C C  G++G  C G++   C    C     C +      C
Sbjct: 771  CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 830

Query: 991  VCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE-- 1047
            +C  G+ G  C T MD  A +  P  + H      +  C C   W+G  C+  + S +  
Sbjct: 831  LCPTGYTGGSCQTLMDLCAQKPCPR-NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKA 889

Query: 1048 -----------CGPHGRCV--GES--CSCAAGWSGEFCS--VRLCDARCAEHG-----QC 1085
                       C   G CV  G S  C C  G+ G  C   V  C++R  ++G     Q 
Sbjct: 890  ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 949

Query: 1086 KNGTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G++C+  L+ C  + C  HG C     G + C C  G+ G  C
Sbjct: 950  SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC-TPKPGGFHCACPPGFVGLRC 1003



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 87/310 (28%), Positives = 112/310 (36%), Gaps = 55/310 (17%)

Query: 878  CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYINGE-----CQCNP 928
            C NG  C   G      C C PGF G  C   V  C     Q G     +     CQC P
Sbjct: 901  CHNGGLCVDSGPSYF--CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP 958

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC-GEID-C---P-HP- 977
            G+ G+ CS   D C+   C+ HG C        C+C  G+ G  C G++D C   P HP 
Sbjct: 959  GYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1018

Query: 978  -TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-----CSCH 1031
             T + H       C C  G  G  C  ++ D     P C   GT +    +     C C 
Sbjct: 1019 GTAACHSLANAFYCQCLPGHTGQWC-EVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCP 1076

Query: 1032 AKWSGEDCSKEVCSL---ECGPHGRCVGE-------SCSCAAGWSGEFCSVRLCDARCAE 1081
              + G  CS    S     C   G C+          C+C +G+ G  C        C  
Sbjct: 1077 KGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGP 1136

Query: 1082 HGQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRV---------DNDGRWECKCF-- 1129
               C  NG+C   +G  G       CP S  G  +C+            DG  +  C   
Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRC-SCPHSSPG-PRCQKPGAKGCEGRSGDGACDAGCSGP 1194

Query: 1130 -DGWDGPDCT 1138
               WDG DC+
Sbjct: 1195 GGNWDGGDCS 1204



 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 84/308 (27%), Positives = 116/308 (37%), Gaps = 62/308 (20%)

Query: 922  GECQCNPGWKGKECSLRHDECEVPD-CNGHGHCV------------------NGKCSCVR 962
            G CQC PG+ G+ C    D C+    C   G C                   +  C+C+ 
Sbjct: 49   GTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 107

Query: 963  GYKGKFCG---EIDCPHPTCSGHGFC-IEGT----CVCKKGWKGADCGTMDKDALQCLPD 1014
            G+ G+ C    E  CP   CS  G C I+ +    C C  GW G  C    +D     P 
Sbjct: 108  GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL--RDFCSANPC 165

Query: 1015 CSGHGTFDVDTQT-CSCHAKWSGEDCSKEV--CSLECGP-------HGRCVGESCSCAAG 1064
             +G        Q  C C   + G  C ++V  C  + GP       H       C C  G
Sbjct: 166  VNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225

Query: 1065 WSGEFCSVRL--CDAR-CAEHGQC-----KNGT---CLCVSGWNGRHCTL--EGC-PRSC 1110
              G  C +R   C  R C+  G C     K+ T   CLC  G+ G  C +  + C    C
Sbjct: 226  QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
               G C+ D    + C C + W G DC+       +D  + +  G   C +   CQ+ A 
Sbjct: 286  QNGGTCQ-DGLDTYTCLCPETWTGWDCS-------EDVDECETQGPPHCRNGGTCQNSAG 337

Query: 1171 KSSQLCVS 1178
                +CVS
Sbjct: 338  SFHCVCVS 345



 Score = 77.4 bits (182), Expect = 7e-13
 Identities = 81/302 (26%), Positives = 110/302 (36%), Gaps = 59/302 (19%)

Query: 893  CQCQPGFGG-------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKECSLRHDECE 943
            C C  G+ G       D C++  CP    C Q G   +  C C  GW G  C+L    C+
Sbjct: 830  CLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFH--CLCLQGWTGPLCNLPLSSCQ 887

Query: 944  VPD----------CNGHGHCVNGK----CSCVRGYKGKFCGEI--DCPHPTCSGHGFCIE 987
                         C+  G CV+      C C  G++G  C +    C    C     C+ 
Sbjct: 888  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMA 947

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT--CSCHAKWSGEDCSK 1041
                  C C  G+ G +C + + DA Q  P C  HGT         C+C   + G  C  
Sbjct: 948  QPSGYLCQCAPGYDGQNC-SKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEG 1005

Query: 1042 EV--C-SLECGPHGRCVGES------CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT- 1089
            +V  C    C P G     S      C C  G +G++C V +  C ++   HG     T 
Sbjct: 1006 DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATA 1065

Query: 1090 -------CLCVSGWNGRHCT--LEGCP-RSCAGHGQCRVDNDGRW--ECKCFDGWDGPDC 1137
                   C C  G+ G  C+     C    C   G C       +   C C  G+ GPDC
Sbjct: 1066 GSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDC 1125

Query: 1138 TT 1139
             T
Sbjct: 1126 LT 1127



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 86/311 (27%), Positives = 110/311 (35%), Gaps = 56/311 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ------------ 925
            CP G S         C C  G  G  C     P  C  RG    G CQ            
Sbjct: 205  CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP--CPPRGCSNGGTCQLMPEKDSTFHLC 262

Query: 926  -CNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP--- 975
             C PG+ G +C +  D C    C   G C +G     C C   + G  C E +D C    
Sbjct: 263  LCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQG 322

Query: 976  HPTCSGHGFCIEGT----CVCKKGWKGADC--GTMDKDALQCLPDCSGHGTFD-VDTQTC 1028
             P C   G C        CVC  GW G  C     D  A  C P   G    D V + +C
Sbjct: 323  PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAP---GSTCIDRVGSFSC 379

Query: 1029 SCHAKWSGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFCSVRLCDARCA 1080
             C    +G  C  +++C S  C    +C      G + C C  G+SG  C   L +   A
Sbjct: 380  LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 439

Query: 1081 EHG--QCKNG----------TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWEC 1126
            + G   C++G           CLC  G+ G  C  +   C       G   +D    + C
Sbjct: 440  QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499

Query: 1127 KCFDGWDGPDC 1137
             C  G +G  C
Sbjct: 500  LCPPGLEGQLC 510



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 102/384 (26%), Positives = 137/384 (35%), Gaps = 74/384 (19%)

Query: 871  AEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--C-PVLCSQRGEYING 922
            +EEMT  C +G C   G C       +C C P   G  C  S   C    C   G  +N 
Sbjct: 727  SEEMTA-CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785

Query: 923  ----ECQCNPGWKGKECSLR-HDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID 973
                 C C  G++G  C  +    C    C     C +     +C C  GY G  C  + 
Sbjct: 786  PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLM 845

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCG----TMDKDALQCLPDCSG---HGT 1020
              C    C  +  C++      C+C +GW G  C     +  K AL    D S    +G 
Sbjct: 846  DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905

Query: 1021 FDVDTQT---CSCHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFC 1070
              VD+     C C   + G  C   V  C S  C     C+    G  C CA G+ G+ C
Sbjct: 906  LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 965

Query: 1071 SVRL--CDAR-CAEHGQC--KNGT--CLCVSGWNGRHCT--LEGC---PRSCAGHGQCRV 1118
            S  L  C ++ C  HG C  K G   C C  G+ G  C   ++ C   P    G   C  
Sbjct: 966  SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACH- 1024

Query: 1119 DNDGRWECKCFDGWDGPDCTTLKEQI----------CDDSRDNDKDGLVDC----EDPEC 1164
                 + C+C  G  G  C    +            C+ +  +    +  C    E P C
Sbjct: 1025 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084

Query: 1165 ------CQSPACKSSQLCVSSPKP 1182
                  C    C    LC+ SPKP
Sbjct: 1085 SHRAPSCGFHHCHHGGLCLPSPKP 1108



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 84/299 (28%), Positives = 108/299 (36%), Gaps = 58/299 (19%)

Query: 892  HCQCQPGFGG-------DDCSKSVC-PVLCSQRGEYING-ECQCNPGWKGKECSLRHDEC 942
            HC C PGF G       D+C    C P   +      N   CQC PG  G+ C +  D C
Sbjct: 991  HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPC 1050

Query: 943  EVPDCNGHGHC-------VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEGT---- 989
                C   G C       +   C C +G++G  C      C    C   G C+       
Sbjct: 1051 HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGF 1110

Query: 990  ---CVCKKGWKGADCGTMDKDALQCLPD--CSGHGTFDVDTQT------CSCHAKWSGED 1038
               C C  G+ G DC T       C P   C  +G+    T        CSC     G  
Sbjct: 1111 PPRCACLSGYGGPDCLTPPAPK-GCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPR 1169

Query: 1039 CSK---EVCSLECGPHGRCVGESCSCAAG-WSGEFCSVRLCDA--RCAEHGQC----KNG 1088
            C K   + C    G  G C    CS   G W G  CS+ + D    C  H +C    ++G
Sbjct: 1170 CQKPGAKGCEGRSGD-GAC-DAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDG 1227

Query: 1089 TCLCVSGWNGRHCTLEG--C--PRSCA-GHGQCRVDN--DGRWECKCFD---GWDGPDC 1137
             C      +   C  +G  C  P +C   + Q   D+  +G  E  C     GWDG DC
Sbjct: 1228 QCH--PQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDC 1284



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 70/263 (26%), Positives = 89/263 (33%), Gaps = 56/263 (21%)

Query: 892  HCQCQPGFGGDDCSKSVCPV---------LC-SQRGEYINGECQCNPGWKGKECSLRHDE 941
            +CQC PG  G  C   + P           C +  G  +   C C  G++G  CS R   
Sbjct: 1031 YCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS 1090

Query: 942  CEVPDCNGHGHCVNG-------KCSCVRGYKGKFC----GEIDCPHPT-CSGHGFCIEGT 989
            C    C+  G C+         +C+C+ GY G  C        C  P+ C  +G C E T
Sbjct: 1091 CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETT 1150

Query: 990  --------CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHA-KWSGEDCS 1040
                    C C     G  C    K   +     SG G  D     CS     W G DCS
Sbjct: 1151 GLGGPGFRCSCPHSSPGPRC---QKPGAKGCEGRSGDGACDAG---CSGPGGNWDGGDCS 1204

Query: 1041 KEVCS--LECGPHGRC--VGESCSCAAGWSGEFC--------SVRLC----DARCAEH-- 1082
              V      C  H RC  +     C      E C        +   C    D  C +H  
Sbjct: 1205 LGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFH 1264

Query: 1083 -GQCKNGTCLCVSGWNGRHCTLE 1104
             G C+ G      GW+G  C  E
Sbjct: 1265 NGHCEKGCNTAECGWDGGDCRPE 1287



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 44/165 (26%), Positives = 56/165 (33%), Gaps = 31/165 (18%)

Query: 874  MTHNCPNGCSGKGECLM-GHCQCQPGFGGD----DCSKSVCPVLCSQRG----EYINGEC 924
            +T   P GC     CL  G C    G GG      C  S     C + G    E  +G+ 
Sbjct: 1126 LTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDG 1185

Query: 925  QCNPGWKGKECSLRHDECE--VPD----CNGHGHCV----NGKCSCVRGYKGKFCGEIDC 974
             C+ G  G   +    +C   VPD    C  H  C     +G+C      +       DC
Sbjct: 1186 ACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDC 1245

Query: 975  PHPT---------CSGH---GFCIEGTCVCKKGWKGADCGTMDKD 1007
              P          C  H   G C +G    + GW G DC   D D
Sbjct: 1246 ETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGD 1290


>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
          Length = 1999

 Score =  118 bits (284), Expect = 3e-25
 Identities = 100/345 (28%), Positives = 139/345 (40%), Gaps = 45/345 (13%)

Query: 874  MTHNCPNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---CSQRGEYIN----G 922
            M    P+ C   G CL      +C C PG+ G  C       L   C      ++     
Sbjct: 437  MAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATF 496

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGE-ID-CPH 976
             C C PG +G+ C +  +EC    C  H  C   +NG +C C+ G+ G  C E ID C  
Sbjct: 497  HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 556

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CS 1029
              C+  G C +      C C  G++G  C T   +  +CL D    G   +D      C 
Sbjct: 557  SPCANGGQCQDQPGAFHCKCLPGFEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCL 613

Query: 1030 CHAKWSGEDCSKEVCSLE-CGPHGRCVGE----SCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            C + ++G+ C   +C+   C P   C  +    +C C  G  G  C+    +  C  HG 
Sbjct: 614  CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGH 670

Query: 1085 CKNGTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC---- 1137
            C+  +C+C  GW G  C  E  GC    CA  G C     G + C C  G+ GP C    
Sbjct: 671  CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEM 729

Query: 1138 TTLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACK-SSQLCVSSP 1180
            T      C +    N   G   C  P     P C+ S+  CVS+P
Sbjct: 730  TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 774



 Score =  114 bits (275), Expect = 4e-24
 Identities = 100/349 (28%), Positives = 136/349 (38%), Gaps = 51/349 (14%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C----PVLCSQRGEYING----E 923
            ++H C NG + +       C C   + G DCS+ V  C    P  C   G   N      
Sbjct: 280  VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFH 339

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID-CPHPT 978
            C C  GW G  C    D+C    C     C++      C C  G  G  C   D C    
Sbjct: 340  CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 399

Query: 979  CSGHGFC----IEGT--CVCKKGWKGADCGTMDKDALQCL-----PDCSGHGTFDVDTQ- 1026
            C G   C    + G+  C+C+ G+ G  C    +D  +CL     P    HG   ++T  
Sbjct: 400  CHGDAQCSTNPLTGSTLCLCQPGYSGPTC---HQDLDECLMAQQGPSPCEHGGSCLNTPG 456

Query: 1027 --TCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--- 1074
               C C   ++G  C     E  S  C P   C+       C C  G  G+ C V     
Sbjct: 457  SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 516

Query: 1075 CDARCAEHGQCK---NG-TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECK 1127
              A C  H  C    NG  C+C+ G++G  C   ++ C  S CA  GQC+ D  G + CK
Sbjct: 517  ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ-DQPGAFHCK 575

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
            C  G++GP C T  ++   D        L D      C  P+  + QLC
Sbjct: 576  CLPGFEGPRCQTEVDECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLC 623



 Score =  104 bits (250), Expect = 4e-21
 Identities = 91/292 (31%), Positives = 120/292 (41%), Gaps = 51/292 (17%)

Query: 893  CQCQPGFGGDDCSKSV---CPV-LCSQRGE-YING----ECQCNPGWKGKECSLRHDECE 943
            C C PGF G+ C   +   CP   CS+RG  +I      +C C PGW G++C LR D C 
Sbjct: 102  CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCS 160

Query: 944  VPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDC---PHPTCSG---HGFCIEGTCV 991
               C   G C+      +C C  G++G  C     +C   P P   G   H       C+
Sbjct: 161  ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 220

Query: 992  CKKGWKGADCGTMDKDALQCLP-DCSGHGTF------DVDTQTCSCHAKWSGEDC--SKE 1042
            C  G +G  C   +  A  C P  CS  GT       D     C C   + G  C  + +
Sbjct: 221  CPVGQEGPRC---ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPD 277

Query: 1043 VC-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR----CAEHGQCKNGT-- 1089
             C S +C   G C       +C C   W+G  CS  V  C+A+    C   G C+N    
Sbjct: 278  NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGS 337

Query: 1090 --CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+CVSGW G  C   L+ C  +    G   +D  G + C C  G  G  C
Sbjct: 338  FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 389



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 96/357 (26%), Positives = 138/357 (38%), Gaps = 55/357 (15%)

Query: 870  VAEEMTHNCPNG-CSGKGEC---LMG-HCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN 921
            + E  T+ C +  C    +C   L G  C C PGF G  C + +  C    C+  G+  +
Sbjct: 508  LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD 567

Query: 922  G----ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCGEID 973
                  C+C PG++G  C    DEC    C     C++  G   C C  G+ G+ C    
Sbjct: 568  QPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL 627

Query: 974  CPHPTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            C    C     C +      C+C  G  G  C   + D   C      HG       +C 
Sbjct: 628  CAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPE-DNCTC-----HHG--HCQRSSCV 677

Query: 1030 CHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-C 1079
            C   W+G +C  E+  C S  C   G C     G +C+C  G++G  CS  +  C +  C
Sbjct: 678  CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC 737

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGW 1132
               G C        C C     G  C  + + C  + C   G C V+  G + C C  G+
Sbjct: 738  LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC-VNRPGTFSCLCAMGF 796

Query: 1133 DGPDCTTLKEQICDDSRDNDKDGLVDC-EDPEC-CQS----PACKS-SQLCVSSPKP 1182
             GP C       C DS   ++    D  + P C C +     +C++   LC   P P
Sbjct: 797  QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCP 853



 Score = 89.0 bits (211), Expect = 2e-16
 Identities = 81/295 (27%), Positives = 115/295 (38%), Gaps = 54/295 (18%)

Query: 892  HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGE----------CQCNPGWKGKECSLRHDE 941
            +C C  G+ G  CS+ +    C   G  +NG           C C P   G +C    D 
Sbjct: 713  NCTCPTGYTGPTCSEEM--TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDY 769

Query: 942  CEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI--DCPHPTCSGHGFCIEG----TC 990
            C    C   G CVN      C C  G++G  C G++   C    C     C +      C
Sbjct: 770  CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 829

Query: 991  VCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE-- 1047
            +C  G+ G  C T MD  A +  P  + H      +  C C   W+G  C+  + S +  
Sbjct: 830  LCPTGYTGGSCQTLMDLCAQKPCPR-NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKA 888

Query: 1048 -----------CGPHGRCV--GES--CSCAAGWSGEFCS--VRLCDARCAEHG-----QC 1085
                       C   G CV  G S  C C  G+ G  C   V  C++R  ++G     Q 
Sbjct: 889  ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 948

Query: 1086 KNGTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G++C+  L+ C  + C  HG C     G + C C  G+ G  C
Sbjct: 949  SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC-TPKPGGFHCACPPGFVGLRC 1002



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 87/310 (28%), Positives = 112/310 (36%), Gaps = 55/310 (17%)

Query: 878  CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYINGE-----CQCNP 928
            C NG  C   G      C C PGF G  C   V  C     Q G     +     CQC P
Sbjct: 900  CHNGGLCVDSGPSYF--CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP 957

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC-GEID-C---P-HP- 977
            G+ G+ CS   D C+   C+ HG C        C+C  G+ G  C G++D C   P HP 
Sbjct: 958  GYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1017

Query: 978  -TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-----CSCH 1031
             T + H       C C  G  G  C  ++ D     P C   GT +    +     C C 
Sbjct: 1018 GTAACHSLANAFYCQCLPGHTGQWC-EVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCP 1075

Query: 1032 AKWSGEDCSKEVCSL---ECGPHGRCVGE-------SCSCAAGWSGEFCSVRLCDARCAE 1081
              + G  CS    S     C   G C+          C+C +G+ G  C        C  
Sbjct: 1076 KGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGP 1135

Query: 1082 HGQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRV---------DNDGRWECKCF-- 1129
               C  NG+C   +G  G       CP S  G  +C+            DG  +  C   
Sbjct: 1136 PSPCLYNGSCSETTGLGGPGFRC-SCPHSSPG-PRCQKPGAKGCEGRSGDGACDAGCSGP 1193

Query: 1130 -DGWDGPDCT 1138
               WDG DC+
Sbjct: 1194 GGNWDGGDCS 1203



 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 84/308 (27%), Positives = 116/308 (37%), Gaps = 62/308 (20%)

Query: 922  GECQCNPGWKGKECSLRHDECEVPD-CNGHGHCV------------------NGKCSCVR 962
            G CQC PG+ G+ C    D C+    C   G C                   +  C+C+ 
Sbjct: 48   GTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 106

Query: 963  GYKGKFCG---EIDCPHPTCSGHGFC-IEGT----CVCKKGWKGADCGTMDKDALQCLPD 1014
            G+ G+ C    E  CP   CS  G C I+ +    C C  GW G  C    +D     P 
Sbjct: 107  GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL--RDFCSANPC 164

Query: 1015 CSGHGTFDVDTQT-CSCHAKWSGEDCSKEV--CSLECGP-------HGRCVGESCSCAAG 1064
             +G        Q  C C   + G  C ++V  C  + GP       H       C C  G
Sbjct: 165  VNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 224

Query: 1065 WSGEFCSVRL--CDAR-CAEHGQC-----KNGT---CLCVSGWNGRHCTL--EGC-PRSC 1110
              G  C +R   C  R C+  G C     K+ T   CLC  G+ G  C +  + C    C
Sbjct: 225  QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQC 284

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
               G C+ D    + C C + W G DC+       +D  + +  G   C +   CQ+ A 
Sbjct: 285  QNGGTCQ-DGLDTYTCLCPETWTGWDCS-------EDVDECEAQGPPHCRNGGTCQNSAG 336

Query: 1171 KSSQLCVS 1178
                +CVS
Sbjct: 337  SFHCVCVS 344



 Score = 77.4 bits (182), Expect = 7e-13
 Identities = 81/302 (26%), Positives = 110/302 (36%), Gaps = 59/302 (19%)

Query: 893  CQCQPGFGG-------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKECSLRHDECE 943
            C C  G+ G       D C++  CP    C Q G   +  C C  GW G  C+L    C+
Sbjct: 829  CLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFH--CLCLQGWTGPLCNLPLSSCQ 886

Query: 944  VPD----------CNGHGHCVNGK----CSCVRGYKGKFCGEI--DCPHPTCSGHGFCIE 987
                         C+  G CV+      C C  G++G  C +    C    C     C+ 
Sbjct: 887  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMA 946

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT--CSCHAKWSGEDCSK 1041
                  C C  G+ G +C + + DA Q  P C  HGT         C+C   + G  C  
Sbjct: 947  QPSGYLCQCAPGYDGQNC-SKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEG 1004

Query: 1042 EV--C-SLECGPHGRCVGES------CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT- 1089
            +V  C    C P G     S      C C  G +G++C V +  C ++   HG     T 
Sbjct: 1005 DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATA 1064

Query: 1090 -------CLCVSGWNGRHCT--LEGCP-RSCAGHGQCRVDNDGRW--ECKCFDGWDGPDC 1137
                   C C  G+ G  C+     C    C   G C       +   C C  G+ GPDC
Sbjct: 1065 GSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDC 1124

Query: 1138 TT 1139
             T
Sbjct: 1125 LT 1126



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 102/384 (26%), Positives = 137/384 (35%), Gaps = 74/384 (19%)

Query: 871  AEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--C-PVLCSQRGEYING 922
            +EEMT  C +G C   G C       +C C P   G  C  S   C    C   G  +N 
Sbjct: 726  SEEMTA-CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 784

Query: 923  ----ECQCNPGWKGKECSLR-HDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID 973
                 C C  G++G  C  +    C    C     C +     +C C  GY G  C  + 
Sbjct: 785  PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLM 844

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCG----TMDKDALQCLPDCSG---HGT 1020
              C    C  +  C++      C+C +GW G  C     +  K AL    D S    +G 
Sbjct: 845  DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 904

Query: 1021 FDVDTQT---CSCHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFC 1070
              VD+     C C   + G  C   V  C S  C     C+    G  C CA G+ G+ C
Sbjct: 905  LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 964

Query: 1071 SVRL--CDAR-CAEHGQC--KNGT--CLCVSGWNGRHCT--LEGC---PRSCAGHGQCRV 1118
            S  L  C ++ C  HG C  K G   C C  G+ G  C   ++ C   P    G   C  
Sbjct: 965  SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACH- 1023

Query: 1119 DNDGRWECKCFDGWDGPDCTTLKEQI----------CDDSRDNDKDGLVDC----EDPEC 1164
                 + C+C  G  G  C    +            C+ +  +    +  C    E P C
Sbjct: 1024 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1083

Query: 1165 ------CQSPACKSSQLCVSSPKP 1182
                  C    C    LC+ SPKP
Sbjct: 1084 SHRAPSCGFHHCHHGGLCLPSPKP 1107



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 84/299 (28%), Positives = 108/299 (36%), Gaps = 58/299 (19%)

Query: 892  HCQCQPGFGG-------DDCSKSVC-PVLCSQRGEYING-ECQCNPGWKGKECSLRHDEC 942
            HC C PGF G       D+C    C P   +      N   CQC PG  G+ C +  D C
Sbjct: 990  HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPC 1049

Query: 943  EVPDCNGHGHC-------VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEGT---- 989
                C   G C       +   C C +G++G  C      C    C   G C+       
Sbjct: 1050 HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGF 1109

Query: 990  ---CVCKKGWKGADCGTMDKDALQCLPD--CSGHGTFDVDTQT------CSCHAKWSGED 1038
               C C  G+ G DC T       C P   C  +G+    T        CSC     G  
Sbjct: 1110 PPRCACLSGYGGPDCLTPPAPK-GCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPR 1168

Query: 1039 CSK---EVCSLECGPHGRCVGESCSCAAG-WSGEFCSVRLCDA--RCAEHGQC----KNG 1088
            C K   + C    G  G C    CS   G W G  CS+ + D    C  H +C    ++G
Sbjct: 1169 CQKPGAKGCEGRSGD-GAC-DAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDG 1226

Query: 1089 TCLCVSGWNGRHCTLEG--C--PRSCA-GHGQCRVDN--DGRWECKCFD---GWDGPDC 1137
             C      +   C  +G  C  P +C   + Q   D+  +G  E  C     GWDG DC
Sbjct: 1227 QCH--PQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDC 1283



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 70/263 (26%), Positives = 89/263 (33%), Gaps = 56/263 (21%)

Query: 892  HCQCQPGFGGDDCSKSVCPV---------LC-SQRGEYINGECQCNPGWKGKECSLRHDE 941
            +CQC PG  G  C   + P           C +  G  +   C C  G++G  CS R   
Sbjct: 1030 YCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS 1089

Query: 942  CEVPDCNGHGHCVNG-------KCSCVRGYKGKFC----GEIDCPHPT-CSGHGFCIEGT 989
            C    C+  G C+         +C+C+ GY G  C        C  P+ C  +G C E T
Sbjct: 1090 CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETT 1149

Query: 990  --------CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHA-KWSGEDCS 1040
                    C C     G  C    K   +     SG G  D     CS     W G DCS
Sbjct: 1150 GLGGPGFRCSCPHSSPGPRC---QKPGAKGCEGRSGDGACDAG---CSGPGGNWDGGDCS 1203

Query: 1041 KEVCS--LECGPHGRC--VGESCSCAAGWSGEFC--------SVRLC----DARCAEH-- 1082
              V      C  H RC  +     C      E C        +   C    D  C +H  
Sbjct: 1204 LGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFH 1263

Query: 1083 -GQCKNGTCLCVSGWNGRHCTLE 1104
             G C+ G      GW+G  C  E
Sbjct: 1264 NGHCEKGCNTAECGWDGGDCRPE 1286



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 44/165 (26%), Positives = 56/165 (33%), Gaps = 31/165 (18%)

Query: 874  MTHNCPNGCSGKGECLM-GHCQCQPGFGGD----DCSKSVCPVLCSQRG----EYINGEC 924
            +T   P GC     CL  G C    G GG      C  S     C + G    E  +G+ 
Sbjct: 1125 LTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDG 1184

Query: 925  QCNPGWKGKECSLRHDECE--VPD----CNGHGHCV----NGKCSCVRGYKGKFCGEIDC 974
             C+ G  G   +    +C   VPD    C  H  C     +G+C      +       DC
Sbjct: 1185 ACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDC 1244

Query: 975  PHPT---------CSGH---GFCIEGTCVCKKGWKGADCGTMDKD 1007
              P          C  H   G C +G    + GW G DC   D D
Sbjct: 1245 ETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGD 1289


>D86566-1|BAA13116.1|  955|Homo sapiens notch related protein protein.
          Length = 955

 Score =  118 bits (284), Expect = 3e-25
 Identities = 100/345 (28%), Positives = 139/345 (40%), Gaps = 45/345 (13%)

Query: 874  MTHNCPNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---CSQRGEYIN----G 922
            M    P+ C   G CL      +C C PG+ G  C       L   C      ++     
Sbjct: 438  MAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATF 497

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGE-ID-CPH 976
             C C PG +G+ C +  +EC    C  H  C   +NG +C C+ G+ G  C E ID C  
Sbjct: 498  HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 557

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CS 1029
              C+  G C +      C C  G++G  C T   +  +CL D    G   +D      C 
Sbjct: 558  SPCANGGQCQDQPGAFHCKCLPGFEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCL 614

Query: 1030 CHAKWSGEDCSKEVCSLE-CGPHGRCVGE----SCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            C + ++G+ C   +C+   C P   C  +    +C C  G  G  C+    +  C  HG 
Sbjct: 615  CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGH 671

Query: 1085 CKNGTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC---- 1137
            C+  +C+C  GW G  C  E  GC    CA  G C     G + C C  G+ GP C    
Sbjct: 672  CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEM 730

Query: 1138 TTLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACK-SSQLCVSSP 1180
            T      C +    N   G   C  P     P C+ S+  CVS+P
Sbjct: 731  TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 775



 Score =  114 bits (275), Expect = 4e-24
 Identities = 100/349 (28%), Positives = 136/349 (38%), Gaps = 51/349 (14%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C----PVLCSQRGEYING----E 923
            ++H C NG + +       C C   + G DCS+ V  C    P  C   G   N      
Sbjct: 281  VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID-CPHPT 978
            C C  GW G  C    D+C    C     C++      C C  G  G  C   D C    
Sbjct: 341  CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 400

Query: 979  CSGHGFC----IEGT--CVCKKGWKGADCGTMDKDALQCL-----PDCSGHGTFDVDTQ- 1026
            C G   C    + G+  C+C+ G+ G  C    +D  +CL     P    HG   ++T  
Sbjct: 401  CHGDAQCSTNPLTGSTLCLCQPGYSGPTC---HQDLDECLMAQQGPSPCEHGGSCLNTPG 457

Query: 1027 --TCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--- 1074
               C C   ++G  C     E  S  C P   C+       C C  G  G+ C V     
Sbjct: 458  SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517

Query: 1075 CDARCAEHGQCK---NG-TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECK 1127
              A C  H  C    NG  C+C+ G++G  C   ++ C  S CA  GQC+ D  G + CK
Sbjct: 518  ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ-DQPGAFHCK 576

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
            C  G++GP C T  ++   D        L D      C  P+  + QLC
Sbjct: 577  CLPGFEGPRCQTEVDECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLC 624



 Score =  105 bits (253), Expect = 2e-21
 Identities = 91/292 (31%), Positives = 120/292 (41%), Gaps = 51/292 (17%)

Query: 893  CQCQPGFGGDDCSKSV---CPV-LCSQRGE-YING----ECQCNPGWKGKECSLRHDECE 943
            C C PGF G+ C   +   CP   CS+RG  +I      +C C PGW G++C LR D C 
Sbjct: 103  CTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCS 161

Query: 944  VPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDC---PHPTCSG---HGFCIEGTCV 991
               C   G C+      +C C  G++G  C     +C   P P   G   H       C+
Sbjct: 162  ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 221

Query: 992  CKKGWKGADCGTMDKDALQCLP-DCSGHGTF------DVDTQTCSCHAKWSGEDC--SKE 1042
            C  G +G  C   +  A  C P  CS  GT       D     C C   + G DC  + +
Sbjct: 222  CPVGQEGPRC---ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278

Query: 1043 VC-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR----CAEHGQCKNGT-- 1089
             C S +C   G C       +C C   W+G  CS  V  C+ +    C   G C+N    
Sbjct: 279  NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338

Query: 1090 --CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+CVSGW G  C   L+ C  +    G   +D  G + C C  G  G  C
Sbjct: 339  FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390



 Score = 97.5 bits (232), Expect = 6e-19
 Identities = 92/338 (27%), Positives = 130/338 (38%), Gaps = 53/338 (15%)

Query: 870  VAEEMTHNCPNG-CSGKGEC---LMG-HCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN 921
            + E  T+ C +  C    +C   L G  C C PGF G  C + +  C    C+  G+  +
Sbjct: 509  LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD 568

Query: 922  G----ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCGEID 973
                  C+C PG++G  C    DEC    C     C++  G   C C  G+ G+ C    
Sbjct: 569  QPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL 628

Query: 974  CPHPTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            C    C     C +      C+C  G  G  C   + D   C      HG       +C 
Sbjct: 629  CAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPE-DNCTC-----HHG--HCQRSSCV 678

Query: 1030 CHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-C 1079
            C   W+G +C  E+  C S  C   G C     G +C+C  G++G  CS  +  C +  C
Sbjct: 679  CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC 738

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGW 1132
               G C        C C     G  C  + + C  + C   G C V+  G + C C  G+
Sbjct: 739  LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC-VNRPGTFSCLCAMGF 797

Query: 1133 DGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
             GP C       C DS   ++     C+D    Q P C
Sbjct: 798  QGPRCEGKLRPSCADSPCRNR---ATCQDSP--QGPRC 830



 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 84/308 (27%), Positives = 116/308 (37%), Gaps = 62/308 (20%)

Query: 922  GECQCNPGWKGKECSLRHDECEVPD-CNGHGHCV------------------NGKCSCVR 962
            G CQC PG+ G+ C    D C+    C   G C                   +  C+C+ 
Sbjct: 49   GTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 107

Query: 963  GYKGKFCG---EIDCPHPTCSGHGFC-IEGT----CVCKKGWKGADCGTMDKDALQCLPD 1014
            G+ G+ C    E  CP   CS  G C I+ +    C C  GW G  C    +D     P 
Sbjct: 108  GFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL--RDFCSANPC 165

Query: 1015 CSGHGTFDVDTQT-CSCHAKWSGEDCSKEV--CSLECGP-------HGRCVGESCSCAAG 1064
             +G        Q  C C   + G  C ++V  C  + GP       H       C C  G
Sbjct: 166  VNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225

Query: 1065 WSGEFCSVRL--CDAR-CAEHGQC-----KNGT---CLCVSGWNGRHCTL--EGC-PRSC 1110
              G  C +R   C  R C+  G C     K+ T   CLC  G+ G  C +  + C    C
Sbjct: 226  QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
               G C+ D    + C C + W G DC+       +D  + +  G   C +   CQ+ A 
Sbjct: 286  QNGGTCQ-DGLDTYTCLCPETWTGWDCS-------EDVDECETQGPPHCRNGGTCQNSAG 337

Query: 1171 KSSQLCVS 1178
                +CVS
Sbjct: 338  SFHCVCVS 345



 Score = 77.8 bits (183), Expect = 6e-13
 Identities = 84/303 (27%), Positives = 105/303 (34%), Gaps = 50/303 (16%)

Query: 879  PNGCSGKGECL----MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            PN C  K  C       +C C  G  G  C+       C   G      C C+ GW G E
Sbjct: 631  PNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGHCQRSSCVCDVGWTGPE 687

Query: 935  CSLRHDECEVPDCNGHGHCV---NG-KCSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEG 988
            C      C    C   G C    +G  C+C  GY G  C E    C    C   G C   
Sbjct: 688  CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPS 747

Query: 989  T----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKE 1042
                 C C     G  C T   D     P C   GT      T +C C   + G  C  +
Sbjct: 748  PGGYYCTCPPSHTGPQCQT-STDYCVSAP-CFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 805

Query: 1043 V---CS-LECGPHGRCV----GESCSCAAGWSGEFCS--VRLCDAR-CAEHGQC-KNGT- 1089
            +   C+   C     C     G  C C  G++G  C   + LC  R C  +  C + G  
Sbjct: 806  LRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQRPCPRNSHCLQTGPS 865

Query: 1090 --CLCVSGWNGRHCT--LEGCPRS-----------CAGHGQCRVDNDGRWECKCFDGWDG 1134
              CLC+ GW G  C   L  C ++           C   G C VD+   + C C  G+ G
Sbjct: 866  FHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLC-VDSGPSYFCHCPPGFQG 924

Query: 1135 PDC 1137
              C
Sbjct: 925  SLC 927



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 86/311 (27%), Positives = 110/311 (35%), Gaps = 56/311 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ------------ 925
            CP G S         C C  G  G  C     P  C  RG    G CQ            
Sbjct: 205  CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP--CPPRGCSNGGTCQLMPEKDSTFHLC 262

Query: 926  -CNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP--- 975
             C PG+ G +C +  D C    C   G C +G     C C   + G  C E +D C    
Sbjct: 263  LCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQG 322

Query: 976  HPTCSGHGFCIEGT----CVCKKGWKGADC--GTMDKDALQCLPDCSGHGTFD-VDTQTC 1028
             P C   G C        CVC  GW G  C     D  A  C P   G    D V + +C
Sbjct: 323  PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAP---GSTCIDRVGSFSC 379

Query: 1029 SCHAKWSGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFCSVRLCDARCA 1080
             C    +G  C  +++C S  C    +C      G + C C  G+SG  C   L +   A
Sbjct: 380  LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 439

Query: 1081 EHG--QCKNG----------TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWEC 1126
            + G   C++G           CLC  G+ G  C  +   C       G   +D    + C
Sbjct: 440  QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499

Query: 1127 KCFDGWDGPDC 1137
             C  G +G  C
Sbjct: 500  LCPPGLEGQLC 510



 Score = 66.1 bits (154), Expect = 2e-09
 Identities = 67/242 (27%), Positives = 92/242 (38%), Gaps = 51/242 (21%)

Query: 892  HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGE----------CQCNPGWKGKECSLRHDE 941
            +C C  G+ G  CS+ +    C   G  +NG           C C P   G +C    D 
Sbjct: 714  NCTCPTGYTGPTCSEEM--TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDY 770

Query: 942  CEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI--DCPHPTCSGHGFCIEG----TC 990
            C    C   G CVN      C C  G++G  C G++   C    C     C +      C
Sbjct: 771  CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 830

Query: 991  VCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE-- 1047
            +C  G+ G  C T MD  A +  P  + H      +  C C   W+G  C+  + S +  
Sbjct: 831  LCPTGYTGGSCQTLMDLCAQRPCPR-NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKA 889

Query: 1048 -----------CGPHGRCV--GES--CSCAAGWSGEFCS--VRLCDARCAEHGQCKNG-T 1089
                       C   G CV  G S  C C  G+ G  C   V  C++R      C+NG T
Sbjct: 890  ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESR-----PCQNGAT 944

Query: 1090 CL 1091
            C+
Sbjct: 945  CM 946


>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
            protein.
          Length = 2003

 Score =  118 bits (284), Expect = 3e-25
 Identities = 100/345 (28%), Positives = 139/345 (40%), Gaps = 45/345 (13%)

Query: 874  MTHNCPNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---CSQRGEYIN----G 922
            M    P+ C   G CL      +C C PG+ G  C       L   C      ++     
Sbjct: 438  MAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATF 497

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGE-ID-CPH 976
             C C PG +G+ C +  +EC    C  H  C   +NG +C C+ G+ G  C E ID C  
Sbjct: 498  HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 557

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CS 1029
              C+  G C +      C C  G++G  C T   +  +CL D    G   +D      C 
Sbjct: 558  SPCANGGQCQDQPGAFHCKCLPGFEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCL 614

Query: 1030 CHAKWSGEDCSKEVCSLE-CGPHGRCVGE----SCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            C + ++G+ C   +C+   C P   C  +    +C C  G  G  C+    +  C  HG 
Sbjct: 615  CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGH 671

Query: 1085 CKNGTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC---- 1137
            C+  +C+C  GW G  C  E  GC    CA  G C     G + C C  G+ GP C    
Sbjct: 672  CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEM 730

Query: 1138 TTLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACK-SSQLCVSSP 1180
            T      C +    N   G   C  P     P C+ S+  CVS+P
Sbjct: 731  TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 775



 Score =  114 bits (275), Expect = 4e-24
 Identities = 100/349 (28%), Positives = 136/349 (38%), Gaps = 51/349 (14%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C----PVLCSQRGEYING----E 923
            ++H C NG + +       C C   + G DCS+ V  C    P  C   G   N      
Sbjct: 281  VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID-CPHPT 978
            C C  GW G  C    D+C    C     C++      C C  G  G  C   D C    
Sbjct: 341  CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 400

Query: 979  CSGHGFC----IEGT--CVCKKGWKGADCGTMDKDALQCL-----PDCSGHGTFDVDTQ- 1026
            C G   C    + G+  C+C+ G+ G  C    +D  +CL     P    HG   ++T  
Sbjct: 401  CHGDAQCSTNPLTGSTLCLCQPGYSGPTC---HQDLDECLMAQQGPSPCEHGGSCLNTPG 457

Query: 1027 --TCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--- 1074
               C C   ++G  C     E  S  C P   C+       C C  G  G+ C V     
Sbjct: 458  SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517

Query: 1075 CDARCAEHGQCK---NG-TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECK 1127
              A C  H  C    NG  C+C+ G++G  C   ++ C  S CA  GQC+ D  G + CK
Sbjct: 518  ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ-DQPGAFHCK 576

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
            C  G++GP C T  ++   D        L D      C  P+  + QLC
Sbjct: 577  CLPGFEGPRCQTEVDECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLC 624



 Score =  105 bits (253), Expect = 2e-21
 Identities = 91/292 (31%), Positives = 120/292 (41%), Gaps = 51/292 (17%)

Query: 893  CQCQPGFGGDDCSKSV---CPV-LCSQRGE-YING----ECQCNPGWKGKECSLRHDECE 943
            C C PGF G+ C   +   CP   CS+RG  +I      +C C PGW G++C LR D C 
Sbjct: 103  CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCS 161

Query: 944  VPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDC---PHPTCSG---HGFCIEGTCV 991
               C   G C+      +C C  G++G  C     +C   P P   G   H       C+
Sbjct: 162  ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 221

Query: 992  CKKGWKGADCGTMDKDALQCLP-DCSGHGTF------DVDTQTCSCHAKWSGEDC--SKE 1042
            C  G +G  C   +  A  C P  CS  GT       D     C C   + G DC  + +
Sbjct: 222  CPVGQEGPRC---ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278

Query: 1043 VC-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR----CAEHGQCKNGT-- 1089
             C S +C   G C       +C C   W+G  CS  V  C+ +    C   G C+N    
Sbjct: 279  NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338

Query: 1090 --CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+CVSGW G  C   L+ C  +    G   +D  G + C C  G  G  C
Sbjct: 339  FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 96/357 (26%), Positives = 138/357 (38%), Gaps = 55/357 (15%)

Query: 870  VAEEMTHNCPNG-CSGKGEC---LMG-HCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN 921
            + E  T+ C +  C    +C   L G  C C PGF G  C + +  C    C+  G+  +
Sbjct: 509  LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD 568

Query: 922  G----ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCGEID 973
                  C+C PG++G  C    DEC    C     C++  G   C C  G+ G+ C    
Sbjct: 569  QPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL 628

Query: 974  CPHPTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            C    C     C +      C+C  G  G  C   + D   C      HG       +C 
Sbjct: 629  CAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPE-DNCTC-----HHG--HCQRSSCV 678

Query: 1030 CHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-C 1079
            C   W+G +C  E+  C S  C   G C     G +C+C  G++G  CS  +  C +  C
Sbjct: 679  CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC 738

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGW 1132
               G C        C C     G  C  + + C  + C   G C V+  G + C C  G+
Sbjct: 739  LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC-VNRPGTFSCLCAMGF 797

Query: 1133 DGPDCTTLKEQICDDSRDNDKDGLVDC-EDPEC-CQS----PACKS-SQLCVSSPKP 1182
             GP C       C DS   ++    D  + P C C +     +C++   LC   P P
Sbjct: 798  QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCP 854



 Score = 89.0 bits (211), Expect = 2e-16
 Identities = 81/295 (27%), Positives = 115/295 (38%), Gaps = 54/295 (18%)

Query: 892  HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGE----------CQCNPGWKGKECSLRHDE 941
            +C C  G+ G  CS+ +    C   G  +NG           C C P   G +C    D 
Sbjct: 714  NCTCPTGYTGPTCSEEM--TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDY 770

Query: 942  CEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI--DCPHPTCSGHGFCIEG----TC 990
            C    C   G CVN      C C  G++G  C G++   C    C     C +      C
Sbjct: 771  CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 830

Query: 991  VCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE-- 1047
            +C  G+ G  C T MD  A +  P  + H      +  C C   W+G  C+  + S +  
Sbjct: 831  LCPTGYTGGSCQTLMDLCAQKPCPR-NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKA 889

Query: 1048 -----------CGPHGRCV--GES--CSCAAGWSGEFCS--VRLCDARCAEHG-----QC 1085
                       C   G CV  G S  C C  G+ G  C   V  C++R  ++G     Q 
Sbjct: 890  ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 949

Query: 1086 KNGTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G++C+  L+ C  + C  HG C     G + C C  G+ G  C
Sbjct: 950  SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC-TPKPGGFHCACPPGFVGLRC 1003



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 87/310 (28%), Positives = 112/310 (36%), Gaps = 55/310 (17%)

Query: 878  CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYINGE-----CQCNP 928
            C NG  C   G      C C PGF G  C   V  C     Q G     +     CQC P
Sbjct: 901  CHNGGLCVDSGPSYF--CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP 958

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC-GEID-C---P-HP- 977
            G+ G+ CS   D C+   C+ HG C        C+C  G+ G  C G++D C   P HP 
Sbjct: 959  GYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1018

Query: 978  -TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-----CSCH 1031
             T + H       C C  G  G  C  ++ D     P C   GT +    +     C C 
Sbjct: 1019 GTAACHSLANAFYCQCLPGHTGQWC-EVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCP 1076

Query: 1032 AKWSGEDCSKEVCSL---ECGPHGRCVGE-------SCSCAAGWSGEFCSVRLCDARCAE 1081
              + G  CS    S     C   G C+          C+C +G+ G  C        C  
Sbjct: 1077 KGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGP 1136

Query: 1082 HGQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRV---------DNDGRWECKCF-- 1129
               C  NG+C   +G  G       CP S  G  +C+            DG  +  C   
Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRC-SCPHSSPG-PRCQKPGAKGCEGRSGDGACDAGCSGP 1194

Query: 1130 -DGWDGPDCT 1138
               WDG DC+
Sbjct: 1195 GGNWDGGDCS 1204



 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 84/308 (27%), Positives = 116/308 (37%), Gaps = 62/308 (20%)

Query: 922  GECQCNPGWKGKECSLRHDECEVPD-CNGHGHCV------------------NGKCSCVR 962
            G CQC PG+ G+ C    D C+    C   G C                   +  C+C+ 
Sbjct: 49   GTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 107

Query: 963  GYKGKFCG---EIDCPHPTCSGHGFC-IEGT----CVCKKGWKGADCGTMDKDALQCLPD 1014
            G+ G+ C    E  CP   CS  G C I+ +    C C  GW G  C    +D     P 
Sbjct: 108  GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL--RDFCSANPC 165

Query: 1015 CSGHGTFDVDTQT-CSCHAKWSGEDCSKEV--CSLECGP-------HGRCVGESCSCAAG 1064
             +G        Q  C C   + G  C ++V  C  + GP       H       C C  G
Sbjct: 166  VNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225

Query: 1065 WSGEFCSVRL--CDAR-CAEHGQC-----KNGT---CLCVSGWNGRHCTL--EGC-PRSC 1110
              G  C +R   C  R C+  G C     K+ T   CLC  G+ G  C +  + C    C
Sbjct: 226  QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
               G C+ D    + C C + W G DC+       +D  + +  G   C +   CQ+ A 
Sbjct: 286  QNGGTCQ-DGLDTYTCLCPETWTGWDCS-------EDVDECETQGPPHCRNGGTCQNSAG 337

Query: 1171 KSSQLCVS 1178
                +CVS
Sbjct: 338  SFHCVCVS 345



 Score = 77.4 bits (182), Expect = 7e-13
 Identities = 81/302 (26%), Positives = 110/302 (36%), Gaps = 59/302 (19%)

Query: 893  CQCQPGFGG-------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKECSLRHDECE 943
            C C  G+ G       D C++  CP    C Q G   +  C C  GW G  C+L    C+
Sbjct: 830  CLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFH--CLCLQGWTGPLCNLPLSSCQ 887

Query: 944  VPD----------CNGHGHCVNGK----CSCVRGYKGKFCGEI--DCPHPTCSGHGFCIE 987
                         C+  G CV+      C C  G++G  C +    C    C     C+ 
Sbjct: 888  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMA 947

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT--CSCHAKWSGEDCSK 1041
                  C C  G+ G +C + + DA Q  P C  HGT         C+C   + G  C  
Sbjct: 948  QPSGYLCQCAPGYDGQNC-SKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEG 1005

Query: 1042 EV--C-SLECGPHGRCVGES------CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT- 1089
            +V  C    C P G     S      C C  G +G++C V +  C ++   HG     T 
Sbjct: 1006 DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATA 1065

Query: 1090 -------CLCVSGWNGRHCT--LEGCP-RSCAGHGQCRVDNDGRW--ECKCFDGWDGPDC 1137
                   C C  G+ G  C+     C    C   G C       +   C C  G+ GPDC
Sbjct: 1066 GSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDC 1125

Query: 1138 TT 1139
             T
Sbjct: 1126 LT 1127



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 86/311 (27%), Positives = 110/311 (35%), Gaps = 56/311 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ------------ 925
            CP G S         C C  G  G  C     P  C  RG    G CQ            
Sbjct: 205  CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP--CPPRGCSNGGTCQLMPEKDSTFHLC 262

Query: 926  -CNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP--- 975
             C PG+ G +C +  D C    C   G C +G     C C   + G  C E +D C    
Sbjct: 263  LCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQG 322

Query: 976  HPTCSGHGFCIEGT----CVCKKGWKGADC--GTMDKDALQCLPDCSGHGTFD-VDTQTC 1028
             P C   G C        CVC  GW G  C     D  A  C P   G    D V + +C
Sbjct: 323  PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAP---GSTCIDRVGSFSC 379

Query: 1029 SCHAKWSGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFCSVRLCDARCA 1080
             C    +G  C  +++C S  C    +C      G + C C  G+SG  C   L +   A
Sbjct: 380  LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 439

Query: 1081 EHG--QCKNG----------TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWEC 1126
            + G   C++G           CLC  G+ G  C  +   C       G   +D    + C
Sbjct: 440  QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499

Query: 1127 KCFDGWDGPDC 1137
             C  G +G  C
Sbjct: 500  LCPPGLEGQLC 510



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 102/384 (26%), Positives = 137/384 (35%), Gaps = 74/384 (19%)

Query: 871  AEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--C-PVLCSQRGEYING 922
            +EEMT  C +G C   G C       +C C P   G  C  S   C    C   G  +N 
Sbjct: 727  SEEMTA-CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785

Query: 923  ----ECQCNPGWKGKECSLR-HDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID 973
                 C C  G++G  C  +    C    C     C +     +C C  GY G  C  + 
Sbjct: 786  PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLM 845

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCG----TMDKDALQCLPDCSG---HGT 1020
              C    C  +  C++      C+C +GW G  C     +  K AL    D S    +G 
Sbjct: 846  DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905

Query: 1021 FDVDTQT---CSCHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFC 1070
              VD+     C C   + G  C   V  C S  C     C+    G  C CA G+ G+ C
Sbjct: 906  LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 965

Query: 1071 SVRL--CDAR-CAEHGQC--KNGT--CLCVSGWNGRHCT--LEGC---PRSCAGHGQCRV 1118
            S  L  C ++ C  HG C  K G   C C  G+ G  C   ++ C   P    G   C  
Sbjct: 966  SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACH- 1024

Query: 1119 DNDGRWECKCFDGWDGPDCTTLKEQI----------CDDSRDNDKDGLVDC----EDPEC 1164
                 + C+C  G  G  C    +            C+ +  +    +  C    E P C
Sbjct: 1025 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084

Query: 1165 ------CQSPACKSSQLCVSSPKP 1182
                  C    C    LC+ SPKP
Sbjct: 1085 SHRAPSCGFHHCHHGGLCLPSPKP 1108



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 84/299 (28%), Positives = 108/299 (36%), Gaps = 58/299 (19%)

Query: 892  HCQCQPGFGG-------DDCSKSVC-PVLCSQRGEYING-ECQCNPGWKGKECSLRHDEC 942
            HC C PGF G       D+C    C P   +      N   CQC PG  G+ C +  D C
Sbjct: 991  HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPC 1050

Query: 943  EVPDCNGHGHC-------VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEGT---- 989
                C   G C       +   C C +G++G  C      C    C   G C+       
Sbjct: 1051 HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGF 1110

Query: 990  ---CVCKKGWKGADCGTMDKDALQCLPD--CSGHGTFDVDTQT------CSCHAKWSGED 1038
               C C  G+ G DC T       C P   C  +G+    T        CSC     G  
Sbjct: 1111 PPRCACLSGYGGPDCLTPPAPK-GCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPR 1169

Query: 1039 CSK---EVCSLECGPHGRCVGESCSCAAG-WSGEFCSVRLCDA--RCAEHGQC----KNG 1088
            C K   + C    G  G C    CS   G W G  CS+ + D    C  H +C    ++G
Sbjct: 1170 CQKPGAKGCEGRSGD-GAC-DAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDG 1227

Query: 1089 TCLCVSGWNGRHCTLEG--C--PRSCA-GHGQCRVDN--DGRWECKCFD---GWDGPDC 1137
             C      +   C  +G  C  P +C   + Q   D+  +G  E  C     GWDG DC
Sbjct: 1228 QCH--PQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDC 1284



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 70/263 (26%), Positives = 89/263 (33%), Gaps = 56/263 (21%)

Query: 892  HCQCQPGFGGDDCSKSVCPV---------LC-SQRGEYINGECQCNPGWKGKECSLRHDE 941
            +CQC PG  G  C   + P           C +  G  +   C C  G++G  CS R   
Sbjct: 1031 YCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS 1090

Query: 942  CEVPDCNGHGHCVNG-------KCSCVRGYKGKFC----GEIDCPHPT-CSGHGFCIEGT 989
            C    C+  G C+         +C+C+ GY G  C        C  P+ C  +G C E T
Sbjct: 1091 CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETT 1150

Query: 990  --------CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHA-KWSGEDCS 1040
                    C C     G  C    K   +     SG G  D     CS     W G DCS
Sbjct: 1151 GLGGPGFRCSCPHSSPGPRC---QKPGAKGCEGRSGDGACDAG---CSGPGGNWDGGDCS 1204

Query: 1041 KEVCS--LECGPHGRC--VGESCSCAAGWSGEFC--------SVRLC----DARCAEH-- 1082
              V      C  H RC  +     C      E C        +   C    D  C +H  
Sbjct: 1205 LGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFH 1264

Query: 1083 -GQCKNGTCLCVSGWNGRHCTLE 1104
             G C+ G      GW+G  C  E
Sbjct: 1265 NGHCEKGCNTAECGWDGGDCRPE 1287



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 44/165 (26%), Positives = 56/165 (33%), Gaps = 31/165 (18%)

Query: 874  MTHNCPNGCSGKGECLM-GHCQCQPGFGGD----DCSKSVCPVLCSQRG----EYINGEC 924
            +T   P GC     CL  G C    G GG      C  S     C + G    E  +G+ 
Sbjct: 1126 LTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDG 1185

Query: 925  QCNPGWKGKECSLRHDECE--VPD----CNGHGHCV----NGKCSCVRGYKGKFCGEIDC 974
             C+ G  G   +    +C   VPD    C  H  C     +G+C      +       DC
Sbjct: 1186 ACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDC 1245

Query: 975  PHPT---------CSGH---GFCIEGTCVCKKGWKGADCGTMDKD 1007
              P          C  H   G C +G    + GW G DC   D D
Sbjct: 1246 ETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGD 1290


>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
            protein.
          Length = 2003

 Score =  118 bits (284), Expect = 3e-25
 Identities = 100/345 (28%), Positives = 139/345 (40%), Gaps = 45/345 (13%)

Query: 874  MTHNCPNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---CSQRGEYIN----G 922
            M    P+ C   G CL      +C C PG+ G  C       L   C      ++     
Sbjct: 438  MAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATF 497

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGE-ID-CPH 976
             C C PG +G+ C +  +EC    C  H  C   +NG +C C+ G+ G  C E ID C  
Sbjct: 498  HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 557

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CS 1029
              C+  G C +      C C  G++G  C T   +  +CL D    G   +D      C 
Sbjct: 558  SPCANGGQCQDQPGAFHCKCLPGFEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCL 614

Query: 1030 CHAKWSGEDCSKEVCSLE-CGPHGRCVGE----SCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            C + ++G+ C   +C+   C P   C  +    +C C  G  G  C+    +  C  HG 
Sbjct: 615  CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGH 671

Query: 1085 CKNGTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC---- 1137
            C+  +C+C  GW G  C  E  GC    CA  G C     G + C C  G+ GP C    
Sbjct: 672  CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEM 730

Query: 1138 TTLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACK-SSQLCVSSP 1180
            T      C +    N   G   C  P     P C+ S+  CVS+P
Sbjct: 731  TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 775



 Score =  114 bits (275), Expect = 4e-24
 Identities = 100/349 (28%), Positives = 136/349 (38%), Gaps = 51/349 (14%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C----PVLCSQRGEYING----E 923
            ++H C NG + +       C C   + G DCS+ V  C    P  C   G   N      
Sbjct: 281  VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID-CPHPT 978
            C C  GW G  C    D+C    C     C++      C C  G  G  C   D C    
Sbjct: 341  CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 400

Query: 979  CSGHGFC----IEGT--CVCKKGWKGADCGTMDKDALQCL-----PDCSGHGTFDVDTQ- 1026
            C G   C    + G+  C+C+ G+ G  C    +D  +CL     P    HG   ++T  
Sbjct: 401  CHGDAQCSTNPLTGSTLCLCQPGYSGPTC---HQDLDECLMAQQGPSPCEHGGSCLNTPG 457

Query: 1027 --TCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--- 1074
               C C   ++G  C     E  S  C P   C+       C C  G  G+ C V     
Sbjct: 458  SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517

Query: 1075 CDARCAEHGQCK---NG-TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECK 1127
              A C  H  C    NG  C+C+ G++G  C   ++ C  S CA  GQC+ D  G + CK
Sbjct: 518  ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ-DQPGAFHCK 576

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
            C  G++GP C T  ++   D        L D      C  P+  + QLC
Sbjct: 577  CLPGFEGPRCQTEVDECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLC 624



 Score =  105 bits (253), Expect = 2e-21
 Identities = 91/292 (31%), Positives = 120/292 (41%), Gaps = 51/292 (17%)

Query: 893  CQCQPGFGGDDCSKSV---CPV-LCSQRGE-YING----ECQCNPGWKGKECSLRHDECE 943
            C C PGF G+ C   +   CP   CS+RG  +I      +C C PGW G++C LR D C 
Sbjct: 103  CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCS 161

Query: 944  VPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDC---PHPTCSG---HGFCIEGTCV 991
               C   G C+      +C C  G++G  C     +C   P P   G   H       C+
Sbjct: 162  ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 221

Query: 992  CKKGWKGADCGTMDKDALQCLP-DCSGHGTF------DVDTQTCSCHAKWSGEDC--SKE 1042
            C  G +G  C   +  A  C P  CS  GT       D     C C   + G DC  + +
Sbjct: 222  CPVGQEGPRC---ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278

Query: 1043 VC-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR----CAEHGQCKNGT-- 1089
             C S +C   G C       +C C   W+G  CS  V  C+ +    C   G C+N    
Sbjct: 279  NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338

Query: 1090 --CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+CVSGW G  C   L+ C  +    G   +D  G + C C  G  G  C
Sbjct: 339  FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 96/357 (26%), Positives = 138/357 (38%), Gaps = 55/357 (15%)

Query: 870  VAEEMTHNCPNG-CSGKGEC---LMG-HCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN 921
            + E  T+ C +  C    +C   L G  C C PGF G  C + +  C    C+  G+  +
Sbjct: 509  LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD 568

Query: 922  G----ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCGEID 973
                  C+C PG++G  C    DEC    C     C++  G   C C  G+ G+ C    
Sbjct: 569  QPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL 628

Query: 974  CPHPTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            C    C     C +      C+C  G  G  C   + D   C      HG       +C 
Sbjct: 629  CAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPE-DNCTC-----HHG--HCQRSSCV 678

Query: 1030 CHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-C 1079
            C   W+G +C  E+  C S  C   G C     G +C+C  G++G  CS  +  C +  C
Sbjct: 679  CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC 738

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGW 1132
               G C        C C     G  C  + + C  + C   G C V+  G + C C  G+
Sbjct: 739  LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC-VNRPGTFSCLCAMGF 797

Query: 1133 DGPDCTTLKEQICDDSRDNDKDGLVDC-EDPEC-CQS----PACKS-SQLCVSSPKP 1182
             GP C       C DS   ++    D  + P C C +     +C++   LC   P P
Sbjct: 798  QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCP 854



 Score = 89.0 bits (211), Expect = 2e-16
 Identities = 81/295 (27%), Positives = 115/295 (38%), Gaps = 54/295 (18%)

Query: 892  HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGE----------CQCNPGWKGKECSLRHDE 941
            +C C  G+ G  CS+ +    C   G  +NG           C C P   G +C    D 
Sbjct: 714  NCTCPTGYTGPTCSEEM--TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDY 770

Query: 942  CEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI--DCPHPTCSGHGFCIEG----TC 990
            C    C   G CVN      C C  G++G  C G++   C    C     C +      C
Sbjct: 771  CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 830

Query: 991  VCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE-- 1047
            +C  G+ G  C T MD  A +  P  + H      +  C C   W+G  C+  + S +  
Sbjct: 831  LCPTGYTGGSCQTLMDLCAQKPCPR-NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKA 889

Query: 1048 -----------CGPHGRCV--GES--CSCAAGWSGEFCS--VRLCDARCAEHG-----QC 1085
                       C   G CV  G S  C C  G+ G  C   V  C++R  ++G     Q 
Sbjct: 890  ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 949

Query: 1086 KNGTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G++C+  L+ C  + C  HG C     G + C C  G+ G  C
Sbjct: 950  SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC-TPKPGGFHCACPPGFVGLRC 1003



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 87/310 (28%), Positives = 112/310 (36%), Gaps = 55/310 (17%)

Query: 878  CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYINGE-----CQCNP 928
            C NG  C   G      C C PGF G  C   V  C     Q G     +     CQC P
Sbjct: 901  CHNGGLCVDSGPSYF--CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP 958

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC-GEID-C---P-HP- 977
            G+ G+ CS   D C+   C+ HG C        C+C  G+ G  C G++D C   P HP 
Sbjct: 959  GYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1018

Query: 978  -TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-----CSCH 1031
             T + H       C C  G  G  C  ++ D     P C   GT +    +     C C 
Sbjct: 1019 GTAACHSLANAFYCQCLPGHTGQWC-EVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCP 1076

Query: 1032 AKWSGEDCSKEVCSL---ECGPHGRCVGE-------SCSCAAGWSGEFCSVRLCDARCAE 1081
              + G  CS    S     C   G C+          C+C +G+ G  C        C  
Sbjct: 1077 KGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGP 1136

Query: 1082 HGQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRV---------DNDGRWECKCF-- 1129
               C  NG+C   +G  G       CP S  G  +C+            DG  +  C   
Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRC-SCPHSSPG-PRCQKPGAKGCEGRSGDGACDAGCSGP 1194

Query: 1130 -DGWDGPDCT 1138
               WDG DC+
Sbjct: 1195 GGNWDGGDCS 1204



 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 84/308 (27%), Positives = 116/308 (37%), Gaps = 62/308 (20%)

Query: 922  GECQCNPGWKGKECSLRHDECEVPD-CNGHGHCV------------------NGKCSCVR 962
            G CQC PG+ G+ C    D C+    C   G C                   +  C+C+ 
Sbjct: 49   GTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 107

Query: 963  GYKGKFCG---EIDCPHPTCSGHGFC-IEGT----CVCKKGWKGADCGTMDKDALQCLPD 1014
            G+ G+ C    E  CP   CS  G C I+ +    C C  GW G  C    +D     P 
Sbjct: 108  GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL--RDFCSANPC 165

Query: 1015 CSGHGTFDVDTQT-CSCHAKWSGEDCSKEV--CSLECGP-------HGRCVGESCSCAAG 1064
             +G        Q  C C   + G  C ++V  C  + GP       H       C C  G
Sbjct: 166  VNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225

Query: 1065 WSGEFCSVRL--CDAR-CAEHGQC-----KNGT---CLCVSGWNGRHCTL--EGC-PRSC 1110
              G  C +R   C  R C+  G C     K+ T   CLC  G+ G  C +  + C    C
Sbjct: 226  QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
               G C+ D    + C C + W G DC+       +D  + +  G   C +   CQ+ A 
Sbjct: 286  QNGGTCQ-DGLDTYTCLCPETWTGWDCS-------EDVDECETQGPPHCRNGGTCQNSAG 337

Query: 1171 KSSQLCVS 1178
                +CVS
Sbjct: 338  SFHCVCVS 345



 Score = 77.4 bits (182), Expect = 7e-13
 Identities = 81/302 (26%), Positives = 110/302 (36%), Gaps = 59/302 (19%)

Query: 893  CQCQPGFGG-------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKECSLRHDECE 943
            C C  G+ G       D C++  CP    C Q G   +  C C  GW G  C+L    C+
Sbjct: 830  CLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFH--CLCLQGWTGPLCNLPLSSCQ 887

Query: 944  VPD----------CNGHGHCVNGK----CSCVRGYKGKFCGEI--DCPHPTCSGHGFCIE 987
                         C+  G CV+      C C  G++G  C +    C    C     C+ 
Sbjct: 888  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMA 947

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT--CSCHAKWSGEDCSK 1041
                  C C  G+ G +C + + DA Q  P C  HGT         C+C   + G  C  
Sbjct: 948  QPSGYLCQCAPGYDGQNC-SKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEG 1005

Query: 1042 EV--C-SLECGPHGRCVGES------CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT- 1089
            +V  C    C P G     S      C C  G +G++C V +  C ++   HG     T 
Sbjct: 1006 DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATA 1065

Query: 1090 -------CLCVSGWNGRHCT--LEGCP-RSCAGHGQCRVDNDGRW--ECKCFDGWDGPDC 1137
                   C C  G+ G  C+     C    C   G C       +   C C  G+ GPDC
Sbjct: 1066 GSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDC 1125

Query: 1138 TT 1139
             T
Sbjct: 1126 LT 1127



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 86/311 (27%), Positives = 110/311 (35%), Gaps = 56/311 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ------------ 925
            CP G S         C C  G  G  C     P  C  RG    G CQ            
Sbjct: 205  CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP--CPPRGCSNGGTCQLMPEKDSTFHLC 262

Query: 926  -CNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP--- 975
             C PG+ G +C +  D C    C   G C +G     C C   + G  C E +D C    
Sbjct: 263  LCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQG 322

Query: 976  HPTCSGHGFCIEGT----CVCKKGWKGADC--GTMDKDALQCLPDCSGHGTFD-VDTQTC 1028
             P C   G C        CVC  GW G  C     D  A  C P   G    D V + +C
Sbjct: 323  PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAP---GSTCIDRVGSFSC 379

Query: 1029 SCHAKWSGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFCSVRLCDARCA 1080
             C    +G  C  +++C S  C    +C      G + C C  G+SG  C   L +   A
Sbjct: 380  LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 439

Query: 1081 EHG--QCKNG----------TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWEC 1126
            + G   C++G           CLC  G+ G  C  +   C       G   +D    + C
Sbjct: 440  QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499

Query: 1127 KCFDGWDGPDC 1137
             C  G +G  C
Sbjct: 500  LCPPGLEGQLC 510



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 102/384 (26%), Positives = 137/384 (35%), Gaps = 74/384 (19%)

Query: 871  AEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--C-PVLCSQRGEYING 922
            +EEMT  C +G C   G C       +C C P   G  C  S   C    C   G  +N 
Sbjct: 727  SEEMTA-CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785

Query: 923  ----ECQCNPGWKGKECSLR-HDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID 973
                 C C  G++G  C  +    C    C     C +     +C C  GY G  C  + 
Sbjct: 786  PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLM 845

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCG----TMDKDALQCLPDCSG---HGT 1020
              C    C  +  C++      C+C +GW G  C     +  K AL    D S    +G 
Sbjct: 846  DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905

Query: 1021 FDVDTQT---CSCHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFC 1070
              VD+     C C   + G  C   V  C S  C     C+    G  C CA G+ G+ C
Sbjct: 906  LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 965

Query: 1071 SVRL--CDAR-CAEHGQC--KNGT--CLCVSGWNGRHCT--LEGC---PRSCAGHGQCRV 1118
            S  L  C ++ C  HG C  K G   C C  G+ G  C   ++ C   P    G   C  
Sbjct: 966  SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACH- 1024

Query: 1119 DNDGRWECKCFDGWDGPDCTTLKEQI----------CDDSRDNDKDGLVDC----EDPEC 1164
                 + C+C  G  G  C    +            C+ +  +    +  C    E P C
Sbjct: 1025 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084

Query: 1165 ------CQSPACKSSQLCVSSPKP 1182
                  C    C    LC+ SPKP
Sbjct: 1085 SHRAPSCGFHHCHHGGLCLPSPKP 1108



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 84/299 (28%), Positives = 108/299 (36%), Gaps = 58/299 (19%)

Query: 892  HCQCQPGFGG-------DDCSKSVC-PVLCSQRGEYING-ECQCNPGWKGKECSLRHDEC 942
            HC C PGF G       D+C    C P   +      N   CQC PG  G+ C +  D C
Sbjct: 991  HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPC 1050

Query: 943  EVPDCNGHGHC-------VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEGT---- 989
                C   G C       +   C C +G++G  C      C    C   G C+       
Sbjct: 1051 HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGF 1110

Query: 990  ---CVCKKGWKGADCGTMDKDALQCLPD--CSGHGTFDVDTQT------CSCHAKWSGED 1038
               C C  G+ G DC T       C P   C  +G+    T        CSC     G  
Sbjct: 1111 PPRCACLSGYGGPDCLTPPAPK-GCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPR 1169

Query: 1039 CSK---EVCSLECGPHGRCVGESCSCAAG-WSGEFCSVRLCDA--RCAEHGQC----KNG 1088
            C K   + C    G  G C    CS   G W G  CS+ + D    C  H +C    ++G
Sbjct: 1170 CQKPGAKGCEGRSGD-GAC-DAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDG 1227

Query: 1089 TCLCVSGWNGRHCTLEG--C--PRSCA-GHGQCRVDN--DGRWECKCFD---GWDGPDC 1137
             C      +   C  +G  C  P +C   + Q   D+  +G  E  C     GWDG DC
Sbjct: 1228 QCH--PQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDC 1284



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 70/263 (26%), Positives = 89/263 (33%), Gaps = 56/263 (21%)

Query: 892  HCQCQPGFGGDDCSKSVCPV---------LC-SQRGEYINGECQCNPGWKGKECSLRHDE 941
            +CQC PG  G  C   + P           C +  G  +   C C  G++G  CS R   
Sbjct: 1031 YCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS 1090

Query: 942  CEVPDCNGHGHCVNG-------KCSCVRGYKGKFC----GEIDCPHPT-CSGHGFCIEGT 989
            C    C+  G C+         +C+C+ GY G  C        C  P+ C  +G C E T
Sbjct: 1091 CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETT 1150

Query: 990  --------CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHA-KWSGEDCS 1040
                    C C     G  C    K   +     SG G  D     CS     W G DCS
Sbjct: 1151 GLGGPGFRCSCPHSSPGPRC---QKPGAKGCEGRSGDGACDAG---CSGPGGNWDGGDCS 1204

Query: 1041 KEVCS--LECGPHGRC--VGESCSCAAGWSGEFC--------SVRLC----DARCAEH-- 1082
              V      C  H RC  +     C      E C        +   C    D  C +H  
Sbjct: 1205 LGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFH 1264

Query: 1083 -GQCKNGTCLCVSGWNGRHCTLE 1104
             G C+ G      GW+G  C  E
Sbjct: 1265 NGHCEKGCNTAECGWDGGDCRPE 1287



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 44/165 (26%), Positives = 56/165 (33%), Gaps = 31/165 (18%)

Query: 874  MTHNCPNGCSGKGECLM-GHCQCQPGFGGD----DCSKSVCPVLCSQRG----EYINGEC 924
            +T   P GC     CL  G C    G GG      C  S     C + G    E  +G+ 
Sbjct: 1126 LTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDG 1185

Query: 925  QCNPGWKGKECSLRHDECE--VPD----CNGHGHCV----NGKCSCVRGYKGKFCGEIDC 974
             C+ G  G   +    +C   VPD    C  H  C     +G+C      +       DC
Sbjct: 1186 ACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDC 1245

Query: 975  PHPT---------CSGH---GFCIEGTCVCKKGWKGADCGTMDKD 1007
              P          C  H   G C +G    + GW G DC   D D
Sbjct: 1246 ETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGD 1290


>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
            protein.
          Length = 2003

 Score =  118 bits (284), Expect = 3e-25
 Identities = 100/345 (28%), Positives = 139/345 (40%), Gaps = 45/345 (13%)

Query: 874  MTHNCPNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---CSQRGEYIN----G 922
            M    P+ C   G CL      +C C PG+ G  C       L   C      ++     
Sbjct: 438  MAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATF 497

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGE-ID-CPH 976
             C C PG +G+ C +  +EC    C  H  C   +NG +C C+ G+ G  C E ID C  
Sbjct: 498  HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 557

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CS 1029
              C+  G C +      C C  G++G  C T   +  +CL D    G   +D      C 
Sbjct: 558  SPCANGGQCQDQPGAFHCKCLPGFEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCL 614

Query: 1030 CHAKWSGEDCSKEVCSLE-CGPHGRCVGE----SCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            C + ++G+ C   +C+   C P   C  +    +C C  G  G  C+    +  C  HG 
Sbjct: 615  CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGH 671

Query: 1085 CKNGTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC---- 1137
            C+  +C+C  GW G  C  E  GC    CA  G C     G + C C  G+ GP C    
Sbjct: 672  CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEM 730

Query: 1138 TTLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACK-SSQLCVSSP 1180
            T      C +    N   G   C  P     P C+ S+  CVS+P
Sbjct: 731  TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 775



 Score =  114 bits (275), Expect = 4e-24
 Identities = 100/349 (28%), Positives = 136/349 (38%), Gaps = 51/349 (14%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C----PVLCSQRGEYING----E 923
            ++H C NG + +       C C   + G DCS+ V  C    P  C   G   N      
Sbjct: 281  VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID-CPHPT 978
            C C  GW G  C    D+C    C     C++      C C  G  G  C   D C    
Sbjct: 341  CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 400

Query: 979  CSGHGFC----IEGT--CVCKKGWKGADCGTMDKDALQCL-----PDCSGHGTFDVDTQ- 1026
            C G   C    + G+  C+C+ G+ G  C    +D  +CL     P    HG   ++T  
Sbjct: 401  CHGDAQCSTNPLTGSTLCLCQPGYSGPTC---HQDLDECLMAQQGPSPCEHGGSCLNTPG 457

Query: 1027 --TCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--- 1074
               C C   ++G  C     E  S  C P   C+       C C  G  G+ C V     
Sbjct: 458  SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517

Query: 1075 CDARCAEHGQCK---NG-TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECK 1127
              A C  H  C    NG  C+C+ G++G  C   ++ C  S CA  GQC+ D  G + CK
Sbjct: 518  ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ-DQPGAFHCK 576

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
            C  G++GP C T  ++   D        L D      C  P+  + QLC
Sbjct: 577  CLPGFEGPRCQTEVDECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLC 624



 Score =  105 bits (253), Expect = 2e-21
 Identities = 91/292 (31%), Positives = 120/292 (41%), Gaps = 51/292 (17%)

Query: 893  CQCQPGFGGDDCSKSV---CPV-LCSQRGE-YING----ECQCNPGWKGKECSLRHDECE 943
            C C PGF G+ C   +   CP   CS+RG  +I      +C C PGW G++C LR D C 
Sbjct: 103  CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCS 161

Query: 944  VPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDC---PHPTCSG---HGFCIEGTCV 991
               C   G C+      +C C  G++G  C     +C   P P   G   H       C+
Sbjct: 162  ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 221

Query: 992  CKKGWKGADCGTMDKDALQCLP-DCSGHGTF------DVDTQTCSCHAKWSGEDC--SKE 1042
            C  G +G  C   +  A  C P  CS  GT       D     C C   + G DC  + +
Sbjct: 222  CPVGQEGPRC---ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278

Query: 1043 VC-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR----CAEHGQCKNGT-- 1089
             C S +C   G C       +C C   W+G  CS  V  C+ +    C   G C+N    
Sbjct: 279  NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338

Query: 1090 --CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+CVSGW G  C   L+ C  +    G   +D  G + C C  G  G  C
Sbjct: 339  FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 91/344 (26%), Positives = 129/344 (37%), Gaps = 48/344 (13%)

Query: 870  VAEEMTHNCPNG-CSGKGEC---LMG-HCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN 921
            + E  T+ C +  C    +C   L G  C C PGF G  C + +  C    C+  G+  +
Sbjct: 509  LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD 568

Query: 922  G----ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCGEID 973
                  C+C PG++G  C    DEC    C     C++  G   C C  G+ G+ C    
Sbjct: 569  QPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL 628

Query: 974  CPHPTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            C    C     C +      C+C  G  G  C   + D   C      HG       +C 
Sbjct: 629  CAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPE-DNCTC-----HHG--HCQRSSCV 678

Query: 1030 CHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-C 1079
            C   W+G +C  E+  C S  C   G C     G +C+C  G++G  CS  +  C +  C
Sbjct: 679  CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC 738

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGW 1132
               G C        C C     G  C  + + C  + C   G C V+  G + C C  G+
Sbjct: 739  LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC-VNRPGTFSCLCAMGF 797

Query: 1133 DGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
             GP C       C DS   ++    D      C  P   +   C
Sbjct: 798  QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGSC 841



 Score = 85.4 bits (202), Expect = 3e-15
 Identities = 80/295 (27%), Positives = 114/295 (38%), Gaps = 54/295 (18%)

Query: 892  HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGE----------CQCNPGWKGKECSLRHDE 941
            +C C  G+ G  CS+ +    C   G  +NG           C C P   G +C    D 
Sbjct: 714  NCTCPTGYTGPTCSEEM--TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDY 770

Query: 942  CEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI--DCPHPTCSGHGFCIEG----TC 990
            C    C   G CVN      C C  G++G  C G++   C    C     C +      C
Sbjct: 771  CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 830

Query: 991  VCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE-- 1047
            +C   + G  C T MD  A +  P  + H      +  C C   W+G  C+  + S +  
Sbjct: 831  LCPTVYTGGSCQTLMDLCAQKPCPR-NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKA 889

Query: 1048 -----------CGPHGRCV--GES--CSCAAGWSGEFCS--VRLCDARCAEHG-----QC 1085
                       C   G CV  G S  C C  G+ G  C   V  C++R  ++G     Q 
Sbjct: 890  ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 949

Query: 1086 KNGTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G++C+  L+ C  + C  HG C     G + C C  G+ G  C
Sbjct: 950  SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC-TPKPGGFHCACPPGFVGLRC 1003



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 87/310 (28%), Positives = 112/310 (36%), Gaps = 55/310 (17%)

Query: 878  CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYINGE-----CQCNP 928
            C NG  C   G      C C PGF G  C   V  C     Q G     +     CQC P
Sbjct: 901  CHNGGLCVDSGPSYF--CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP 958

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC-GEID-C---P-HP- 977
            G+ G+ CS   D C+   C+ HG C        C+C  G+ G  C G++D C   P HP 
Sbjct: 959  GYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1018

Query: 978  -TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-----CSCH 1031
             T + H       C C  G  G  C  ++ D     P C   GT +    +     C C 
Sbjct: 1019 GTAACHSLANAFYCQCLPGHTGQWC-EVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCP 1076

Query: 1032 AKWSGEDCSKEVCSL---ECGPHGRCVGE-------SCSCAAGWSGEFCSVRLCDARCAE 1081
              + G  CS    S     C   G C+          C+C +G+ G  C        C  
Sbjct: 1077 KGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGP 1136

Query: 1082 HGQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRV---------DNDGRWECKCF-- 1129
               C  NG+C   +G  G       CP S  G  +C+            DG  +  C   
Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRC-SCPHSSPG-PRCQKPGAKGCEGRSGDGACDAGCSGP 1194

Query: 1130 -DGWDGPDCT 1138
               WDG DC+
Sbjct: 1195 GGNWDGGDCS 1204



 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 84/308 (27%), Positives = 116/308 (37%), Gaps = 62/308 (20%)

Query: 922  GECQCNPGWKGKECSLRHDECEVPD-CNGHGHCV------------------NGKCSCVR 962
            G CQC PG+ G+ C    D C+    C   G C                   +  C+C+ 
Sbjct: 49   GTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 107

Query: 963  GYKGKFCG---EIDCPHPTCSGHGFC-IEGT----CVCKKGWKGADCGTMDKDALQCLPD 1014
            G+ G+ C    E  CP   CS  G C I+ +    C C  GW G  C    +D     P 
Sbjct: 108  GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL--RDFCSANPC 165

Query: 1015 CSGHGTFDVDTQT-CSCHAKWSGEDCSKEV--CSLECGP-------HGRCVGESCSCAAG 1064
             +G        Q  C C   + G  C ++V  C  + GP       H       C C  G
Sbjct: 166  VNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225

Query: 1065 WSGEFCSVRL--CDAR-CAEHGQC-----KNGT---CLCVSGWNGRHCTL--EGC-PRSC 1110
              G  C +R   C  R C+  G C     K+ T   CLC  G+ G  C +  + C    C
Sbjct: 226  QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
               G C+ D    + C C + W G DC+       +D  + +  G   C +   CQ+ A 
Sbjct: 286  QNGGTCQ-DGLDTYTCLCPETWTGWDCS-------EDVDECETQGPPHCRNGGTCQNSAG 337

Query: 1171 KSSQLCVS 1178
                +CVS
Sbjct: 338  SFHCVCVS 345



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 86/311 (27%), Positives = 110/311 (35%), Gaps = 56/311 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ------------ 925
            CP G S         C C  G  G  C     P  C  RG    G CQ            
Sbjct: 205  CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP--CPPRGCSNGGTCQLMPEKDSTFHLC 262

Query: 926  -CNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP--- 975
             C PG+ G +C +  D C    C   G C +G     C C   + G  C E +D C    
Sbjct: 263  LCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQG 322

Query: 976  HPTCSGHGFCIEGT----CVCKKGWKGADC--GTMDKDALQCLPDCSGHGTFD-VDTQTC 1028
             P C   G C        CVC  GW G  C     D  A  C P   G    D V + +C
Sbjct: 323  PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAP---GSTCIDRVGSFSC 379

Query: 1029 SCHAKWSGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFCSVRLCDARCA 1080
             C    +G  C  +++C S  C    +C      G + C C  G+SG  C   L +   A
Sbjct: 380  LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 439

Query: 1081 EHG--QCKNG----------TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWEC 1126
            + G   C++G           CLC  G+ G  C  +   C       G   +D    + C
Sbjct: 440  QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499

Query: 1127 KCFDGWDGPDC 1137
             C  G +G  C
Sbjct: 500  LCPPGLEGQLC 510



 Score = 75.8 bits (178), Expect = 2e-12
 Identities = 77/286 (26%), Positives = 105/286 (36%), Gaps = 52/286 (18%)

Query: 902  DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPD----------CNG 949
            D C++  CP    C Q G   +  C C  GW G  C+L    C+             C+ 
Sbjct: 846  DLCAQKPCPRNSHCLQTGPSFH--CLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHN 903

Query: 950  HGHCVNGK----CSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEGT----CVCKKGWKGA 999
             G CV+      C C  G++G  C +    C    C     C+       C C  G+ G 
Sbjct: 904  GGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQ 963

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQT--CSCHAKWSGEDCSKEV--C-SLECGPHGRC 1054
            +C + + DA Q  P C  HGT         C+C   + G  C  +V  C    C P G  
Sbjct: 964  NC-SKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA 1021

Query: 1055 VGES------CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT--------CLCVSGWNG 1098
               S      C C  G +G++C V +  C ++   HG     T        C C  G+ G
Sbjct: 1022 ACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEG 1081

Query: 1099 RHCT--LEGCP-RSCAGHGQCRVDNDGRW--ECKCFDGWDGPDCTT 1139
              C+     C    C   G C       +   C C  G+ GPDC T
Sbjct: 1082 PTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLT 1127



 Score = 73.3 bits (172), Expect = 1e-11
 Identities = 101/384 (26%), Positives = 136/384 (35%), Gaps = 74/384 (19%)

Query: 871  AEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--C-PVLCSQRGEYING 922
            +EEMT  C +G C   G C       +C C P   G  C  S   C    C   G  +N 
Sbjct: 727  SEEMTA-CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785

Query: 923  ----ECQCNPGWKGKECSLR-HDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID 973
                 C C  G++G  C  +    C    C     C +     +C C   Y G  C  + 
Sbjct: 786  PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGSCQTLM 845

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCG----TMDKDALQCLPDCSG---HGT 1020
              C    C  +  C++      C+C +GW G  C     +  K AL    D S    +G 
Sbjct: 846  DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905

Query: 1021 FDVDTQT---CSCHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFC 1070
              VD+     C C   + G  C   V  C S  C     C+    G  C CA G+ G+ C
Sbjct: 906  LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 965

Query: 1071 SVRL--CDAR-CAEHGQC--KNGT--CLCVSGWNGRHCT--LEGC---PRSCAGHGQCRV 1118
            S  L  C ++ C  HG C  K G   C C  G+ G  C   ++ C   P    G   C  
Sbjct: 966  SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACH- 1024

Query: 1119 DNDGRWECKCFDGWDGPDCTTLKEQI----------CDDSRDNDKDGLVDC----EDPEC 1164
                 + C+C  G  G  C    +            C+ +  +    +  C    E P C
Sbjct: 1025 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084

Query: 1165 ------CQSPACKSSQLCVSSPKP 1182
                  C    C    LC+ SPKP
Sbjct: 1085 SHRAPSCGFHHCHHGGLCLPSPKP 1108



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 84/299 (28%), Positives = 108/299 (36%), Gaps = 58/299 (19%)

Query: 892  HCQCQPGFGG-------DDCSKSVC-PVLCSQRGEYING-ECQCNPGWKGKECSLRHDEC 942
            HC C PGF G       D+C    C P   +      N   CQC PG  G+ C +  D C
Sbjct: 991  HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPC 1050

Query: 943  EVPDCNGHGHC-------VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEGT---- 989
                C   G C       +   C C +G++G  C      C    C   G C+       
Sbjct: 1051 HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGF 1110

Query: 990  ---CVCKKGWKGADCGTMDKDALQCLPD--CSGHGTFDVDTQT------CSCHAKWSGED 1038
               C C  G+ G DC T       C P   C  +G+    T        CSC     G  
Sbjct: 1111 PPRCACLSGYGGPDCLTPPAPK-GCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPR 1169

Query: 1039 CSK---EVCSLECGPHGRCVGESCSCAAG-WSGEFCSVRLCDA--RCAEHGQC----KNG 1088
            C K   + C    G  G C    CS   G W G  CS+ + D    C  H +C    ++G
Sbjct: 1170 CQKPGAKGCEGRSGD-GAC-DAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDG 1227

Query: 1089 TCLCVSGWNGRHCTLEG--C--PRSCA-GHGQCRVDN--DGRWECKCFD---GWDGPDC 1137
             C      +   C  +G  C  P +C   + Q   D+  +G  E  C     GWDG DC
Sbjct: 1228 QCH--PQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDC 1284



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 70/263 (26%), Positives = 89/263 (33%), Gaps = 56/263 (21%)

Query: 892  HCQCQPGFGGDDCSKSVCPV---------LC-SQRGEYINGECQCNPGWKGKECSLRHDE 941
            +CQC PG  G  C   + P           C +  G  +   C C  G++G  CS R   
Sbjct: 1031 YCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS 1090

Query: 942  CEVPDCNGHGHCVNG-------KCSCVRGYKGKFC----GEIDCPHPT-CSGHGFCIEGT 989
            C    C+  G C+         +C+C+ GY G  C        C  P+ C  +G C E T
Sbjct: 1091 CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETT 1150

Query: 990  --------CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHA-KWSGEDCS 1040
                    C C     G  C    K   +     SG G  D     CS     W G DCS
Sbjct: 1151 GLGGPGFRCSCPHSSPGPRC---QKPGAKGCEGRSGDGACDAG---CSGPGGNWDGGDCS 1204

Query: 1041 KEVCS--LECGPHGRC--VGESCSCAAGWSGEFC--------SVRLC----DARCAEH-- 1082
              V      C  H RC  +     C      E C        +   C    D  C +H  
Sbjct: 1205 LGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFH 1264

Query: 1083 -GQCKNGTCLCVSGWNGRHCTLE 1104
             G C+ G      GW+G  C  E
Sbjct: 1265 NGHCEKGCNTAECGWDGGDCRPE 1287



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 44/165 (26%), Positives = 56/165 (33%), Gaps = 31/165 (18%)

Query: 874  MTHNCPNGCSGKGECLM-GHCQCQPGFGGD----DCSKSVCPVLCSQRG----EYINGEC 924
            +T   P GC     CL  G C    G GG      C  S     C + G    E  +G+ 
Sbjct: 1126 LTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDG 1185

Query: 925  QCNPGWKGKECSLRHDECE--VPD----CNGHGHCV----NGKCSCVRGYKGKFCGEIDC 974
             C+ G  G   +    +C   VPD    C  H  C     +G+C      +       DC
Sbjct: 1186 ACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDC 1245

Query: 975  PHPT---------CSGH---GFCIEGTCVCKKGWKGADCGTMDKD 1007
              P          C  H   G C +G    + GW G DC   D D
Sbjct: 1246 ETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGD 1290


>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
            (Drosophila) protein.
          Length = 2003

 Score =  118 bits (284), Expect = 3e-25
 Identities = 100/345 (28%), Positives = 139/345 (40%), Gaps = 45/345 (13%)

Query: 874  MTHNCPNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---CSQRGEYIN----G 922
            M    P+ C   G CL      +C C PG+ G  C       L   C      ++     
Sbjct: 438  MAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATF 497

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGE-ID-CPH 976
             C C PG +G+ C +  +EC    C  H  C   +NG +C C+ G+ G  C E ID C  
Sbjct: 498  HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 557

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CS 1029
              C+  G C +      C C  G++G  C T   +  +CL D    G   +D      C 
Sbjct: 558  SPCANGGQCQDQPGAFHCKCLPGFEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCL 614

Query: 1030 CHAKWSGEDCSKEVCSLE-CGPHGRCVGE----SCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            C + ++G+ C   +C+   C P   C  +    +C C  G  G  C+    +  C  HG 
Sbjct: 615  CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGH 671

Query: 1085 CKNGTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC---- 1137
            C+  +C+C  GW G  C  E  GC    CA  G C     G + C C  G+ GP C    
Sbjct: 672  CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEM 730

Query: 1138 TTLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACK-SSQLCVSSP 1180
            T      C +    N   G   C  P     P C+ S+  CVS+P
Sbjct: 731  TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 775



 Score =  114 bits (275), Expect = 4e-24
 Identities = 100/349 (28%), Positives = 136/349 (38%), Gaps = 51/349 (14%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C----PVLCSQRGEYING----E 923
            ++H C NG + +       C C   + G DCS+ V  C    P  C   G   N      
Sbjct: 281  VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID-CPHPT 978
            C C  GW G  C    D+C    C     C++      C C  G  G  C   D C    
Sbjct: 341  CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 400

Query: 979  CSGHGFC----IEGT--CVCKKGWKGADCGTMDKDALQCL-----PDCSGHGTFDVDTQ- 1026
            C G   C    + G+  C+C+ G+ G  C    +D  +CL     P    HG   ++T  
Sbjct: 401  CHGDAQCSTNPLTGSTLCLCQPGYSGPTC---HQDLDECLMAQQGPSPCEHGGSCLNTPG 457

Query: 1027 --TCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--- 1074
               C C   ++G  C     E  S  C P   C+       C C  G  G+ C V     
Sbjct: 458  SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517

Query: 1075 CDARCAEHGQCK---NG-TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECK 1127
              A C  H  C    NG  C+C+ G++G  C   ++ C  S CA  GQC+ D  G + CK
Sbjct: 518  ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ-DQPGAFHCK 576

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
            C  G++GP C T  ++   D        L D      C  P+  + QLC
Sbjct: 577  CLPGFEGPRCQTEVDECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLC 624



 Score =  105 bits (253), Expect = 2e-21
 Identities = 91/292 (31%), Positives = 120/292 (41%), Gaps = 51/292 (17%)

Query: 893  CQCQPGFGGDDCSKSV---CPV-LCSQRGE-YING----ECQCNPGWKGKECSLRHDECE 943
            C C PGF G+ C   +   CP   CS+RG  +I      +C C PGW G++C LR D C 
Sbjct: 103  CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCS 161

Query: 944  VPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDC---PHPTCSG---HGFCIEGTCV 991
               C   G C+      +C C  G++G  C     +C   P P   G   H       C+
Sbjct: 162  ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 221

Query: 992  CKKGWKGADCGTMDKDALQCLP-DCSGHGTF------DVDTQTCSCHAKWSGEDC--SKE 1042
            C  G +G  C   +  A  C P  CS  GT       D     C C   + G DC  + +
Sbjct: 222  CPVGQEGPRC---ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278

Query: 1043 VC-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR----CAEHGQCKNGT-- 1089
             C S +C   G C       +C C   W+G  CS  V  C+ +    C   G C+N    
Sbjct: 279  NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338

Query: 1090 --CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+CVSGW G  C   L+ C  +    G   +D  G + C C  G  G  C
Sbjct: 339  FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 91/344 (26%), Positives = 129/344 (37%), Gaps = 48/344 (13%)

Query: 870  VAEEMTHNCPNG-CSGKGEC---LMG-HCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN 921
            + E  T+ C +  C    +C   L G  C C PGF G  C + +  C    C+  G+  +
Sbjct: 509  LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD 568

Query: 922  G----ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCGEID 973
                  C+C PG++G  C    DEC    C     C++  G   C C  G+ G+ C    
Sbjct: 569  QPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL 628

Query: 974  CPHPTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            C    C     C +      C+C  G  G  C   + D   C      HG       +C 
Sbjct: 629  CAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPE-DNCTC-----HHG--HCQRSSCV 678

Query: 1030 CHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-C 1079
            C   W+G +C  E+  C S  C   G C     G +C+C  G++G  CS  +  C +  C
Sbjct: 679  CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC 738

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGW 1132
               G C        C C     G  C  + + C  + C   G C V+  G + C C  G+
Sbjct: 739  LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC-VNRPGTFSCLCAMGF 797

Query: 1133 DGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
             GP C       C DS   ++    D      C  P   +   C
Sbjct: 798  QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGSC 841



 Score = 85.4 bits (202), Expect = 3e-15
 Identities = 80/295 (27%), Positives = 114/295 (38%), Gaps = 54/295 (18%)

Query: 892  HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGE----------CQCNPGWKGKECSLRHDE 941
            +C C  G+ G  CS+ +    C   G  +NG           C C P   G +C    D 
Sbjct: 714  NCTCPTGYTGPTCSEEM--TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDY 770

Query: 942  CEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI--DCPHPTCSGHGFCIEG----TC 990
            C    C   G CVN      C C  G++G  C G++   C    C     C +      C
Sbjct: 771  CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 830

Query: 991  VCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE-- 1047
            +C   + G  C T MD  A +  P  + H      +  C C   W+G  C+  + S +  
Sbjct: 831  LCPTVYTGGSCQTLMDLCAQKPCPR-NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKA 889

Query: 1048 -----------CGPHGRCV--GES--CSCAAGWSGEFCS--VRLCDARCAEHG-----QC 1085
                       C   G CV  G S  C C  G+ G  C   V  C++R  ++G     Q 
Sbjct: 890  ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 949

Query: 1086 KNGTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G++C+  L+ C  + C  HG C     G + C C  G+ G  C
Sbjct: 950  SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC-TPKPGGFHCACPPGFVGLRC 1003



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 87/310 (28%), Positives = 112/310 (36%), Gaps = 55/310 (17%)

Query: 878  CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYINGE-----CQCNP 928
            C NG  C   G      C C PGF G  C   V  C     Q G     +     CQC P
Sbjct: 901  CHNGGLCVDSGPSYF--CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP 958

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC-GEID-C---P-HP- 977
            G+ G+ CS   D C+   C+ HG C        C+C  G+ G  C G++D C   P HP 
Sbjct: 959  GYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1018

Query: 978  -TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-----CSCH 1031
             T + H       C C  G  G  C  ++ D     P C   GT +    +     C C 
Sbjct: 1019 GTAACHSLANAFYCQCLPGHTGQWC-EVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCP 1076

Query: 1032 AKWSGEDCSKEVCSL---ECGPHGRCVGE-------SCSCAAGWSGEFCSVRLCDARCAE 1081
              + G  CS    S     C   G C+          C+C +G+ G  C        C  
Sbjct: 1077 KGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGP 1136

Query: 1082 HGQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRV---------DNDGRWECKCF-- 1129
               C  NG+C   +G  G       CP S  G  +C+            DG  +  C   
Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRC-SCPHSSPG-PRCQKPGAKGCEGRSGDGACDAGCSGP 1194

Query: 1130 -DGWDGPDCT 1138
               WDG DC+
Sbjct: 1195 GGNWDGGDCS 1204



 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 84/308 (27%), Positives = 116/308 (37%), Gaps = 62/308 (20%)

Query: 922  GECQCNPGWKGKECSLRHDECEVPD-CNGHGHCV------------------NGKCSCVR 962
            G CQC PG+ G+ C    D C+    C   G C                   +  C+C+ 
Sbjct: 49   GTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 107

Query: 963  GYKGKFCG---EIDCPHPTCSGHGFC-IEGT----CVCKKGWKGADCGTMDKDALQCLPD 1014
            G+ G+ C    E  CP   CS  G C I+ +    C C  GW G  C    +D     P 
Sbjct: 108  GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL--RDFCSANPC 165

Query: 1015 CSGHGTFDVDTQT-CSCHAKWSGEDCSKEV--CSLECGP-------HGRCVGESCSCAAG 1064
             +G        Q  C C   + G  C ++V  C  + GP       H       C C  G
Sbjct: 166  VNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225

Query: 1065 WSGEFCSVRL--CDAR-CAEHGQC-----KNGT---CLCVSGWNGRHCTL--EGC-PRSC 1110
              G  C +R   C  R C+  G C     K+ T   CLC  G+ G  C +  + C    C
Sbjct: 226  QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
               G C+ D    + C C + W G DC+       +D  + +  G   C +   CQ+ A 
Sbjct: 286  QNGGTCQ-DGLDTYTCLCPETWTGWDCS-------EDVDECETQGPPHCRNGGTCQNSAG 337

Query: 1171 KSSQLCVS 1178
                +CVS
Sbjct: 338  SFHCVCVS 345



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 86/311 (27%), Positives = 110/311 (35%), Gaps = 56/311 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ------------ 925
            CP G S         C C  G  G  C     P  C  RG    G CQ            
Sbjct: 205  CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP--CPPRGCSNGGTCQLMPEKDSTFHLC 262

Query: 926  -CNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP--- 975
             C PG+ G +C +  D C    C   G C +G     C C   + G  C E +D C    
Sbjct: 263  LCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQG 322

Query: 976  HPTCSGHGFCIEGT----CVCKKGWKGADC--GTMDKDALQCLPDCSGHGTFD-VDTQTC 1028
             P C   G C        CVC  GW G  C     D  A  C P   G    D V + +C
Sbjct: 323  PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAP---GSTCIDRVGSFSC 379

Query: 1029 SCHAKWSGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFCSVRLCDARCA 1080
             C    +G  C  +++C S  C    +C      G + C C  G+SG  C   L +   A
Sbjct: 380  LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 439

Query: 1081 EHG--QCKNG----------TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWEC 1126
            + G   C++G           CLC  G+ G  C  +   C       G   +D    + C
Sbjct: 440  QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499

Query: 1127 KCFDGWDGPDC 1137
             C  G +G  C
Sbjct: 500  LCPPGLEGQLC 510



 Score = 75.8 bits (178), Expect = 2e-12
 Identities = 77/286 (26%), Positives = 105/286 (36%), Gaps = 52/286 (18%)

Query: 902  DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPD----------CNG 949
            D C++  CP    C Q G   +  C C  GW G  C+L    C+             C+ 
Sbjct: 846  DLCAQKPCPRNSHCLQTGPSFH--CLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHN 903

Query: 950  HGHCVNGK----CSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEGT----CVCKKGWKGA 999
             G CV+      C C  G++G  C +    C    C     C+       C C  G+ G 
Sbjct: 904  GGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQ 963

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQT--CSCHAKWSGEDCSKEV--C-SLECGPHGRC 1054
            +C + + DA Q  P C  HGT         C+C   + G  C  +V  C    C P G  
Sbjct: 964  NC-SKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA 1021

Query: 1055 VGES------CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT--------CLCVSGWNG 1098
               S      C C  G +G++C V +  C ++   HG     T        C C  G+ G
Sbjct: 1022 ACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEG 1081

Query: 1099 RHCT--LEGCP-RSCAGHGQCRVDNDGRW--ECKCFDGWDGPDCTT 1139
              C+     C    C   G C       +   C C  G+ GPDC T
Sbjct: 1082 PTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLT 1127



 Score = 73.3 bits (172), Expect = 1e-11
 Identities = 101/384 (26%), Positives = 136/384 (35%), Gaps = 74/384 (19%)

Query: 871  AEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--C-PVLCSQRGEYING 922
            +EEMT  C +G C   G C       +C C P   G  C  S   C    C   G  +N 
Sbjct: 727  SEEMTA-CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785

Query: 923  ----ECQCNPGWKGKECSLR-HDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID 973
                 C C  G++G  C  +    C    C     C +     +C C   Y G  C  + 
Sbjct: 786  PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGSCQTLM 845

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCG----TMDKDALQCLPDCSG---HGT 1020
              C    C  +  C++      C+C +GW G  C     +  K AL    D S    +G 
Sbjct: 846  DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905

Query: 1021 FDVDTQT---CSCHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFC 1070
              VD+     C C   + G  C   V  C S  C     C+    G  C CA G+ G+ C
Sbjct: 906  LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 965

Query: 1071 SVRL--CDAR-CAEHGQC--KNGT--CLCVSGWNGRHCT--LEGC---PRSCAGHGQCRV 1118
            S  L  C ++ C  HG C  K G   C C  G+ G  C   ++ C   P    G   C  
Sbjct: 966  SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACH- 1024

Query: 1119 DNDGRWECKCFDGWDGPDCTTLKEQI----------CDDSRDNDKDGLVDC----EDPEC 1164
                 + C+C  G  G  C    +            C+ +  +    +  C    E P C
Sbjct: 1025 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084

Query: 1165 ------CQSPACKSSQLCVSSPKP 1182
                  C    C    LC+ SPKP
Sbjct: 1085 SHRAPSCGFHHCHHGGLCLPSPKP 1108



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 84/299 (28%), Positives = 108/299 (36%), Gaps = 58/299 (19%)

Query: 892  HCQCQPGFGG-------DDCSKSVC-PVLCSQRGEYING-ECQCNPGWKGKECSLRHDEC 942
            HC C PGF G       D+C    C P   +      N   CQC PG  G+ C +  D C
Sbjct: 991  HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPC 1050

Query: 943  EVPDCNGHGHC-------VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEGT---- 989
                C   G C       +   C C +G++G  C      C    C   G C+       
Sbjct: 1051 HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGF 1110

Query: 990  ---CVCKKGWKGADCGTMDKDALQCLPD--CSGHGTFDVDTQT------CSCHAKWSGED 1038
               C C  G+ G DC T       C P   C  +G+    T        CSC     G  
Sbjct: 1111 PPRCACLSGYGGPDCLTPPAPK-GCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPR 1169

Query: 1039 CSK---EVCSLECGPHGRCVGESCSCAAG-WSGEFCSVRLCDA--RCAEHGQC----KNG 1088
            C K   + C    G  G C    CS   G W G  CS+ + D    C  H +C    ++G
Sbjct: 1170 CQKPGAKGCEGRSGD-GAC-DAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDG 1227

Query: 1089 TCLCVSGWNGRHCTLEG--C--PRSCA-GHGQCRVDN--DGRWECKCFD---GWDGPDC 1137
             C      +   C  +G  C  P +C   + Q   D+  +G  E  C     GWDG DC
Sbjct: 1228 QCH--PQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDC 1284



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 70/263 (26%), Positives = 89/263 (33%), Gaps = 56/263 (21%)

Query: 892  HCQCQPGFGGDDCSKSVCPV---------LC-SQRGEYINGECQCNPGWKGKECSLRHDE 941
            +CQC PG  G  C   + P           C +  G  +   C C  G++G  CS R   
Sbjct: 1031 YCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS 1090

Query: 942  CEVPDCNGHGHCVNG-------KCSCVRGYKGKFC----GEIDCPHPT-CSGHGFCIEGT 989
            C    C+  G C+         +C+C+ GY G  C        C  P+ C  +G C E T
Sbjct: 1091 CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETT 1150

Query: 990  --------CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHA-KWSGEDCS 1040
                    C C     G  C    K   +     SG G  D     CS     W G DCS
Sbjct: 1151 GLGGPGFRCSCPHSSPGPRC---QKPGAKGCEGRSGDGACDAG---CSGPGGNWDGGDCS 1204

Query: 1041 KEVCS--LECGPHGRC--VGESCSCAAGWSGEFC--------SVRLC----DARCAEH-- 1082
              V      C  H RC  +     C      E C        +   C    D  C +H  
Sbjct: 1205 LGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFH 1264

Query: 1083 -GQCKNGTCLCVSGWNGRHCTLE 1104
             G C+ G      GW+G  C  E
Sbjct: 1265 NGHCEKGCNTAECGWDGGDCRPE 1287



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 44/165 (26%), Positives = 56/165 (33%), Gaps = 31/165 (18%)

Query: 874  MTHNCPNGCSGKGECLM-GHCQCQPGFGGD----DCSKSVCPVLCSQRG----EYINGEC 924
            +T   P GC     CL  G C    G GG      C  S     C + G    E  +G+ 
Sbjct: 1126 LTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDG 1185

Query: 925  QCNPGWKGKECSLRHDECE--VPD----CNGHGHCV----NGKCSCVRGYKGKFCGEIDC 974
             C+ G  G   +    +C   VPD    C  H  C     +G+C      +       DC
Sbjct: 1186 ACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDC 1245

Query: 975  PHPT---------CSGH---GFCIEGTCVCKKGWKGADCGTMDKD 1007
              P          C  H   G C +G    + GW G DC   D D
Sbjct: 1246 ETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGD 1290


>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
            (Drosophila) protein.
          Length = 2003

 Score =  118 bits (284), Expect = 3e-25
 Identities = 100/345 (28%), Positives = 139/345 (40%), Gaps = 45/345 (13%)

Query: 874  MTHNCPNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---CSQRGEYIN----G 922
            M    P+ C   G CL      +C C PG+ G  C       L   C      ++     
Sbjct: 438  MAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATF 497

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGE-ID-CPH 976
             C C PG +G+ C +  +EC    C  H  C   +NG +C C+ G+ G  C E ID C  
Sbjct: 498  HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 557

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CS 1029
              C+  G C +      C C  G++G  C T   +  +CL D    G   +D      C 
Sbjct: 558  SPCANGGQCQDQPGAFHCKCLPGFEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCL 614

Query: 1030 CHAKWSGEDCSKEVCSLE-CGPHGRCVGE----SCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            C + ++G+ C   +C+   C P   C  +    +C C  G  G  C+    +  C  HG 
Sbjct: 615  CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGH 671

Query: 1085 CKNGTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC---- 1137
            C+  +C+C  GW G  C  E  GC    CA  G C     G + C C  G+ GP C    
Sbjct: 672  CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEM 730

Query: 1138 TTLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACK-SSQLCVSSP 1180
            T      C +    N   G   C  P     P C+ S+  CVS+P
Sbjct: 731  TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 775



 Score =  114 bits (275), Expect = 4e-24
 Identities = 100/349 (28%), Positives = 136/349 (38%), Gaps = 51/349 (14%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C----PVLCSQRGEYING----E 923
            ++H C NG + +       C C   + G DCS+ V  C    P  C   G   N      
Sbjct: 281  VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID-CPHPT 978
            C C  GW G  C    D+C    C     C++      C C  G  G  C   D C    
Sbjct: 341  CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 400

Query: 979  CSGHGFC----IEGT--CVCKKGWKGADCGTMDKDALQCL-----PDCSGHGTFDVDTQ- 1026
            C G   C    + G+  C+C+ G+ G  C    +D  +CL     P    HG   ++T  
Sbjct: 401  CHGDAQCSTNPLTGSTLCLCQPGYSGPTC---HQDLDECLMAQQGPSPCEHGGSCLNTPG 457

Query: 1027 --TCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--- 1074
               C C   ++G  C     E  S  C P   C+       C C  G  G+ C V     
Sbjct: 458  SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517

Query: 1075 CDARCAEHGQCK---NG-TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECK 1127
              A C  H  C    NG  C+C+ G++G  C   ++ C  S CA  GQC+ D  G + CK
Sbjct: 518  ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ-DQPGAFHCK 576

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
            C  G++GP C T  ++   D        L D      C  P+  + QLC
Sbjct: 577  CLPGFEGPRCQTEVDECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLC 624



 Score =  105 bits (253), Expect = 2e-21
 Identities = 91/292 (31%), Positives = 120/292 (41%), Gaps = 51/292 (17%)

Query: 893  CQCQPGFGGDDCSKSV---CPV-LCSQRGE-YING----ECQCNPGWKGKECSLRHDECE 943
            C C PGF G+ C   +   CP   CS+RG  +I      +C C PGW G++C LR D C 
Sbjct: 103  CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCS 161

Query: 944  VPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDC---PHPTCSG---HGFCIEGTCV 991
               C   G C+      +C C  G++G  C     +C   P P   G   H       C+
Sbjct: 162  ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 221

Query: 992  CKKGWKGADCGTMDKDALQCLP-DCSGHGTF------DVDTQTCSCHAKWSGEDC--SKE 1042
            C  G +G  C   +  A  C P  CS  GT       D     C C   + G DC  + +
Sbjct: 222  CPVGQEGPRC---ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278

Query: 1043 VC-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR----CAEHGQCKNGT-- 1089
             C S +C   G C       +C C   W+G  CS  V  C+ +    C   G C+N    
Sbjct: 279  NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338

Query: 1090 --CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+CVSGW G  C   L+ C  +    G   +D  G + C C  G  G  C
Sbjct: 339  FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 96/357 (26%), Positives = 138/357 (38%), Gaps = 55/357 (15%)

Query: 870  VAEEMTHNCPNG-CSGKGEC---LMG-HCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN 921
            + E  T+ C +  C    +C   L G  C C PGF G  C + +  C    C+  G+  +
Sbjct: 509  LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD 568

Query: 922  G----ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCGEID 973
                  C+C PG++G  C    DEC    C     C++  G   C C  G+ G+ C    
Sbjct: 569  QPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL 628

Query: 974  CPHPTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            C    C     C +      C+C  G  G  C   + D   C      HG       +C 
Sbjct: 629  CAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPE-DNCTC-----HHG--HCQRSSCV 678

Query: 1030 CHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-C 1079
            C   W+G +C  E+  C S  C   G C     G +C+C  G++G  CS  +  C +  C
Sbjct: 679  CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC 738

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGW 1132
               G C        C C     G  C  + + C  + C   G C V+  G + C C  G+
Sbjct: 739  LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC-VNRPGTFSCLCAMGF 797

Query: 1133 DGPDCTTLKEQICDDSRDNDKDGLVDC-EDPEC-CQS----PACKS-SQLCVSSPKP 1182
             GP C       C DS   ++    D  + P C C +     +C++   LC   P P
Sbjct: 798  QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCP 854



 Score = 89.0 bits (211), Expect = 2e-16
 Identities = 81/295 (27%), Positives = 115/295 (38%), Gaps = 54/295 (18%)

Query: 892  HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGE----------CQCNPGWKGKECSLRHDE 941
            +C C  G+ G  CS+ +    C   G  +NG           C C P   G +C    D 
Sbjct: 714  NCTCPTGYTGPTCSEEM--TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDY 770

Query: 942  CEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI--DCPHPTCSGHGFCIEG----TC 990
            C    C   G CVN      C C  G++G  C G++   C    C     C +      C
Sbjct: 771  CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 830

Query: 991  VCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE-- 1047
            +C  G+ G  C T MD  A +  P  + H      +  C C   W+G  C+  + S +  
Sbjct: 831  LCPTGYTGGSCQTLMDLCAQKPCPR-NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKA 889

Query: 1048 -----------CGPHGRCV--GES--CSCAAGWSGEFCS--VRLCDARCAEHG-----QC 1085
                       C   G CV  G S  C C  G+ G  C   V  C++R  ++G     Q 
Sbjct: 890  ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 949

Query: 1086 KNGTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G++C+  L+ C  + C  HG C     G + C C  G+ G  C
Sbjct: 950  SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC-TPKPGGFHCACPPGFVGLRC 1003



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 87/310 (28%), Positives = 112/310 (36%), Gaps = 55/310 (17%)

Query: 878  CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYINGE-----CQCNP 928
            C NG  C   G      C C PGF G  C   V  C     Q G     +     CQC P
Sbjct: 901  CHNGGLCVDSGPSYF--CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP 958

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC-GEID-C---P-HP- 977
            G+ G+ CS   D C+   C+ HG C        C+C  G+ G  C G++D C   P HP 
Sbjct: 959  GYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1018

Query: 978  -TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-----CSCH 1031
             T + H       C C  G  G  C  ++ D     P C   GT +    +     C C 
Sbjct: 1019 GTAACHSLANAFYCQCLPGHTGQWC-EVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCP 1076

Query: 1032 AKWSGEDCSKEVCSL---ECGPHGRCVGE-------SCSCAAGWSGEFCSVRLCDARCAE 1081
              + G  CS    S     C   G C+          C+C +G+ G  C        C  
Sbjct: 1077 KGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGP 1136

Query: 1082 HGQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRV---------DNDGRWECKCF-- 1129
               C  NG+C   +G  G       CP S  G  +C+            DG  +  C   
Sbjct: 1137 PSPCLYNGSCSETTGLGGPGFRC-SCPHSSPG-PRCQKPGAKGCEGRSGDGACDAGCSGP 1194

Query: 1130 -DGWDGPDCT 1138
               WDG DC+
Sbjct: 1195 GGNWDGGDCS 1204



 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 84/308 (27%), Positives = 116/308 (37%), Gaps = 62/308 (20%)

Query: 922  GECQCNPGWKGKECSLRHDECEVPD-CNGHGHCV------------------NGKCSCVR 962
            G CQC PG+ G+ C    D C+    C   G C                   +  C+C+ 
Sbjct: 49   GTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 107

Query: 963  GYKGKFCG---EIDCPHPTCSGHGFC-IEGT----CVCKKGWKGADCGTMDKDALQCLPD 1014
            G+ G+ C    E  CP   CS  G C I+ +    C C  GW G  C    +D     P 
Sbjct: 108  GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL--RDFCSANPC 165

Query: 1015 CSGHGTFDVDTQT-CSCHAKWSGEDCSKEV--CSLECGP-------HGRCVGESCSCAAG 1064
             +G        Q  C C   + G  C ++V  C  + GP       H       C C  G
Sbjct: 166  VNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225

Query: 1065 WSGEFCSVRL--CDAR-CAEHGQC-----KNGT---CLCVSGWNGRHCTL--EGC-PRSC 1110
              G  C +R   C  R C+  G C     K+ T   CLC  G+ G  C +  + C    C
Sbjct: 226  QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
               G C+ D    + C C + W G DC+       +D  + +  G   C +   CQ+ A 
Sbjct: 286  QNGGTCQ-DGLDTYTCLCPETWTGWDCS-------EDVDECETQGPPHCRNGGTCQNSAG 337

Query: 1171 KSSQLCVS 1178
                +CVS
Sbjct: 338  SFHCVCVS 345



 Score = 77.4 bits (182), Expect = 7e-13
 Identities = 81/302 (26%), Positives = 110/302 (36%), Gaps = 59/302 (19%)

Query: 893  CQCQPGFGG-------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKECSLRHDECE 943
            C C  G+ G       D C++  CP    C Q G   +  C C  GW G  C+L    C+
Sbjct: 830  CLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFH--CLCLQGWTGPLCNLPLSSCQ 887

Query: 944  VPD----------CNGHGHCVNGK----CSCVRGYKGKFCGEI--DCPHPTCSGHGFCIE 987
                         C+  G CV+      C C  G++G  C +    C    C     C+ 
Sbjct: 888  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMA 947

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT--CSCHAKWSGEDCSK 1041
                  C C  G+ G +C + + DA Q  P C  HGT         C+C   + G  C  
Sbjct: 948  QPSGYLCQCAPGYDGQNC-SKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEG 1005

Query: 1042 EV--C-SLECGPHGRCVGES------CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT- 1089
            +V  C    C P G     S      C C  G +G++C V +  C ++   HG     T 
Sbjct: 1006 DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATA 1065

Query: 1090 -------CLCVSGWNGRHCT--LEGCP-RSCAGHGQCRVDNDGRW--ECKCFDGWDGPDC 1137
                   C C  G+ G  C+     C    C   G C       +   C C  G+ GPDC
Sbjct: 1066 GSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDC 1125

Query: 1138 TT 1139
             T
Sbjct: 1126 LT 1127



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 86/311 (27%), Positives = 110/311 (35%), Gaps = 56/311 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ------------ 925
            CP G S         C C  G  G  C     P  C  RG    G CQ            
Sbjct: 205  CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP--CPPRGCSNGGTCQLMPEKDSTFHLC 262

Query: 926  -CNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP--- 975
             C PG+ G +C +  D C    C   G C +G     C C   + G  C E +D C    
Sbjct: 263  LCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQG 322

Query: 976  HPTCSGHGFCIEGT----CVCKKGWKGADC--GTMDKDALQCLPDCSGHGTFD-VDTQTC 1028
             P C   G C        CVC  GW G  C     D  A  C P   G    D V + +C
Sbjct: 323  PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAP---GSTCIDRVGSFSC 379

Query: 1029 SCHAKWSGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFCSVRLCDARCA 1080
             C    +G  C  +++C S  C    +C      G + C C  G+SG  C   L +   A
Sbjct: 380  LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 439

Query: 1081 EHG--QCKNG----------TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWEC 1126
            + G   C++G           CLC  G+ G  C  +   C       G   +D    + C
Sbjct: 440  QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499

Query: 1127 KCFDGWDGPDC 1137
             C  G +G  C
Sbjct: 500  LCPPGLEGQLC 510



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 102/384 (26%), Positives = 137/384 (35%), Gaps = 74/384 (19%)

Query: 871  AEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--C-PVLCSQRGEYING 922
            +EEMT  C +G C   G C       +C C P   G  C  S   C    C   G  +N 
Sbjct: 727  SEEMTA-CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785

Query: 923  ----ECQCNPGWKGKECSLR-HDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID 973
                 C C  G++G  C  +    C    C     C +     +C C  GY G  C  + 
Sbjct: 786  PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLM 845

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCG----TMDKDALQCLPDCSG---HGT 1020
              C    C  +  C++      C+C +GW G  C     +  K AL    D S    +G 
Sbjct: 846  DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905

Query: 1021 FDVDTQT---CSCHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFC 1070
              VD+     C C   + G  C   V  C S  C     C+    G  C CA G+ G+ C
Sbjct: 906  LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 965

Query: 1071 SVRL--CDAR-CAEHGQC--KNGT--CLCVSGWNGRHCT--LEGC---PRSCAGHGQCRV 1118
            S  L  C ++ C  HG C  K G   C C  G+ G  C   ++ C   P    G   C  
Sbjct: 966  SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACH- 1024

Query: 1119 DNDGRWECKCFDGWDGPDCTTLKEQI----------CDDSRDNDKDGLVDC----EDPEC 1164
                 + C+C  G  G  C    +            C+ +  +    +  C    E P C
Sbjct: 1025 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084

Query: 1165 ------CQSPACKSSQLCVSSPKP 1182
                  C    C    LC+ SPKP
Sbjct: 1085 SHRAPSCGFHHCHHGGLCLPSPKP 1108



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 84/299 (28%), Positives = 108/299 (36%), Gaps = 58/299 (19%)

Query: 892  HCQCQPGFGG-------DDCSKSVC-PVLCSQRGEYING-ECQCNPGWKGKECSLRHDEC 942
            HC C PGF G       D+C    C P   +      N   CQC PG  G+ C +  D C
Sbjct: 991  HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPC 1050

Query: 943  EVPDCNGHGHC-------VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEGT---- 989
                C   G C       +   C C +G++G  C      C    C   G C+       
Sbjct: 1051 HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGF 1110

Query: 990  ---CVCKKGWKGADCGTMDKDALQCLPD--CSGHGTFDVDTQT------CSCHAKWSGED 1038
               C C  G+ G DC T       C P   C  +G+    T        CSC     G  
Sbjct: 1111 PPRCACLSGYGGPDCLTPPAPK-GCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPR 1169

Query: 1039 CSK---EVCSLECGPHGRCVGESCSCAAG-WSGEFCSVRLCDA--RCAEHGQC----KNG 1088
            C K   + C    G  G C    CS   G W G  CS+ + D    C  H +C    ++G
Sbjct: 1170 CQKPGAKGCEGRSGD-GAC-DAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDG 1227

Query: 1089 TCLCVSGWNGRHCTLEG--C--PRSCA-GHGQCRVDN--DGRWECKCFD---GWDGPDC 1137
             C      +   C  +G  C  P +C   + Q   D+  +G  E  C     GWDG DC
Sbjct: 1228 QCH--PQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDC 1284



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 70/263 (26%), Positives = 89/263 (33%), Gaps = 56/263 (21%)

Query: 892  HCQCQPGFGGDDCSKSVCPV---------LC-SQRGEYINGECQCNPGWKGKECSLRHDE 941
            +CQC PG  G  C   + P           C +  G  +   C C  G++G  CS R   
Sbjct: 1031 YCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS 1090

Query: 942  CEVPDCNGHGHCVNG-------KCSCVRGYKGKFC----GEIDCPHPT-CSGHGFCIEGT 989
            C    C+  G C+         +C+C+ GY G  C        C  P+ C  +G C E T
Sbjct: 1091 CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETT 1150

Query: 990  --------CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHA-KWSGEDCS 1040
                    C C     G  C    K   +     SG G  D     CS     W G DCS
Sbjct: 1151 GLGGPGFRCSCPHSSPGPRC---QKPGAKGCEGRSGDGACDAG---CSGPGGNWDGGDCS 1204

Query: 1041 KEVCS--LECGPHGRC--VGESCSCAAGWSGEFC--------SVRLC----DARCAEH-- 1082
              V      C  H RC  +     C      E C        +   C    D  C +H  
Sbjct: 1205 LGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFH 1264

Query: 1083 -GQCKNGTCLCVSGWNGRHCTLE 1104
             G C+ G      GW+G  C  E
Sbjct: 1265 NGHCEKGCNTAECGWDGGDCRPE 1287



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 44/165 (26%), Positives = 56/165 (33%), Gaps = 31/165 (18%)

Query: 874  MTHNCPNGCSGKGECLM-GHCQCQPGFGGD----DCSKSVCPVLCSQRG----EYINGEC 924
            +T   P GC     CL  G C    G GG      C  S     C + G    E  +G+ 
Sbjct: 1126 LTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDG 1185

Query: 925  QCNPGWKGKECSLRHDECE--VPD----CNGHGHCV----NGKCSCVRGYKGKFCGEIDC 974
             C+ G  G   +    +C   VPD    C  H  C     +G+C      +       DC
Sbjct: 1186 ACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDC 1245

Query: 975  PHPT---------CSGH---GFCIEGTCVCKKGWKGADCGTMDKD 1007
              P          C  H   G C +G    + GW G DC   D D
Sbjct: 1246 ETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGD 1290


>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosophila)
            protein.
          Length = 2005

 Score =  118 bits (284), Expect = 3e-25
 Identities = 100/345 (28%), Positives = 139/345 (40%), Gaps = 45/345 (13%)

Query: 874  MTHNCPNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---CSQRGEYIN----G 922
            M    P+ C   G CL      +C C PG+ G  C       L   C      ++     
Sbjct: 440  MAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATF 499

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFCGE-ID-CPH 976
             C C PG +G+ C +  +EC    C  H  C   +NG +C C+ G+ G  C E ID C  
Sbjct: 500  HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 559

Query: 977  PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CS 1029
              C+  G C +      C C  G++G  C T   +  +CL D    G   +D      C 
Sbjct: 560  SPCANGGQCQDQPGAFHCKCLPGFEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCL 616

Query: 1030 CHAKWSGEDCSKEVCSLE-CGPHGRCVGE----SCSCAAGWSGEFCSVRLCDARCAEHGQ 1084
            C + ++G+ C   +C+   C P   C  +    +C C  G  G  C+    +  C  HG 
Sbjct: 617  CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGH 673

Query: 1085 CKNGTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC---- 1137
            C+  +C+C  GW G  C  E  GC    CA  G C     G + C C  G+ GP C    
Sbjct: 674  CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG-YNCTCPTGYTGPTCSEEM 732

Query: 1138 TTLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACK-SSQLCVSSP 1180
            T      C +    N   G   C  P     P C+ S+  CVS+P
Sbjct: 733  TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 777



 Score =  114 bits (275), Expect = 4e-24
 Identities = 100/349 (28%), Positives = 136/349 (38%), Gaps = 51/349 (14%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C----PVLCSQRGEYING----E 923
            ++H C NG + +       C C   + G DCS+ V  C    P  C   G   N      
Sbjct: 283  VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFH 342

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID-CPHPT 978
            C C  GW G  C    D+C    C     C++      C C  G  G  C   D C    
Sbjct: 343  CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 402

Query: 979  CSGHGFC----IEGT--CVCKKGWKGADCGTMDKDALQCL-----PDCSGHGTFDVDTQ- 1026
            C G   C    + G+  C+C+ G+ G  C    +D  +CL     P    HG   ++T  
Sbjct: 403  CHGDAQCSTNPLTGSTLCLCQPGYSGPTC---HQDLDECLMAQQGPSPCEHGGSCLNTPG 459

Query: 1027 --TCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--- 1074
               C C   ++G  C     E  S  C P   C+       C C  G  G+ C V     
Sbjct: 460  SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 519

Query: 1075 CDARCAEHGQCK---NG-TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECK 1127
              A C  H  C    NG  C+C+ G++G  C   ++ C  S CA  GQC+ D  G + CK
Sbjct: 520  ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ-DQPGAFHCK 578

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
            C  G++GP C T  ++   D        L D      C  P+  + QLC
Sbjct: 579  CLPGFEGPRCQTEVDECLSDPCPVGASCL-DLPGAFFCLCPSGFTGQLC 626



 Score =  107 bits (257), Expect = 6e-22
 Identities = 92/292 (31%), Positives = 121/292 (41%), Gaps = 51/292 (17%)

Query: 893  CQCQPGFGGDDCSKSV---CPV-LCSQRGE-YING----ECQCNPGWKGKECSLRHDECE 943
            C C PGF G+ C   +   CP   CS+RG  +I      +C C PGW G++C LR D C 
Sbjct: 105  CTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCS 163

Query: 944  VPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDC---PHPTCSG---HGFCIEGTCV 991
               C   G C+      +C C  G++G  C     +C   P P   G   H       C+
Sbjct: 164  ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 223

Query: 992  CKKGWKGADCGTMDKDALQCLP-DCSGHGTF------DVDTQTCSCHAKWSGEDC--SKE 1042
            C  G +G  C   +  A  C P  CS  GT       D     C C   + G DC  + +
Sbjct: 224  CPVGQEGPRC---ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 280

Query: 1043 VC-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR----CAEHGQCKNGT-- 1089
             C S +C   G C       +C C   W+G  CS  V  C+A+    C   G C+N    
Sbjct: 281  NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGS 340

Query: 1090 --CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+CVSGW G  C   L+ C  +    G   +D  G + C C  G  G  C
Sbjct: 341  FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 392



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 96/357 (26%), Positives = 138/357 (38%), Gaps = 55/357 (15%)

Query: 870  VAEEMTHNCPNG-CSGKGEC---LMG-HCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN 921
            + E  T+ C +  C    +C   L G  C C PGF G  C + +  C    C+  G+  +
Sbjct: 511  LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD 570

Query: 922  G----ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCGEID 973
                  C+C PG++G  C    DEC    C     C++  G   C C  G+ G+ C    
Sbjct: 571  QPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL 630

Query: 974  CPHPTCSGHGFCIE----GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            C    C     C +      C+C  G  G  C   + D   C      HG       +C 
Sbjct: 631  CAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPE-DNCTC-----HHG--HCQRSSCV 680

Query: 1030 CHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-C 1079
            C   W+G +C  E+  C S  C   G C     G +C+C  G++G  CS  +  C +  C
Sbjct: 681  CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC 740

Query: 1080 AEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGW 1132
               G C        C C     G  C  + + C  + C   G C V+  G + C C  G+
Sbjct: 741  LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC-VNRPGTFSCLCAMGF 799

Query: 1133 DGPDCTTLKEQICDDSRDNDKDGLVDC-EDPEC-CQS----PACKS-SQLCVSSPKP 1182
             GP C       C DS   ++    D  + P C C +     +C++   LC   P P
Sbjct: 800  QGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCP 856



 Score = 89.0 bits (211), Expect = 2e-16
 Identities = 81/295 (27%), Positives = 115/295 (38%), Gaps = 54/295 (18%)

Query: 892  HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGE----------CQCNPGWKGKECSLRHDE 941
            +C C  G+ G  CS+ +    C   G  +NG           C C P   G +C    D 
Sbjct: 716  NCTCPTGYTGPTCSEEM--TACHS-GPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDY 772

Query: 942  CEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI--DCPHPTCSGHGFCIEG----TC 990
            C    C   G CVN      C C  G++G  C G++   C    C     C +      C
Sbjct: 773  CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 832

Query: 991  VCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE-- 1047
            +C  G+ G  C T MD  A +  P  + H      +  C C   W+G  C+  + S +  
Sbjct: 833  LCPTGYTGGSCQTLMDLCAQKPCPR-NSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKA 891

Query: 1048 -----------CGPHGRCV--GES--CSCAAGWSGEFCS--VRLCDARCAEHG-----QC 1085
                       C   G CV  G S  C C  G+ G  C   V  C++R  ++G     Q 
Sbjct: 892  ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 951

Query: 1086 KNGTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G++C+  L+ C  + C  HG C     G + C C  G+ G  C
Sbjct: 952  SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC-TPKPGGFHCACPPGFVGLRC 1005



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 87/310 (28%), Positives = 112/310 (36%), Gaps = 55/310 (17%)

Query: 878  CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYINGE-----CQCNP 928
            C NG  C   G      C C PGF G  C   V  C     Q G     +     CQC P
Sbjct: 903  CHNGGLCVDSGPSYF--CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP 960

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC-GEID-C---P-HP- 977
            G+ G+ CS   D C+   C+ HG C        C+C  G+ G  C G++D C   P HP 
Sbjct: 961  GYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1020

Query: 978  -TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-----CSCH 1031
             T + H       C C  G  G  C  ++ D     P C   GT +    +     C C 
Sbjct: 1021 GTAACHSLANAFYCQCLPGHTGQWC-EVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCP 1078

Query: 1032 AKWSGEDCSKEVCSL---ECGPHGRCVGE-------SCSCAAGWSGEFCSVRLCDARCAE 1081
              + G  CS    S     C   G C+          C+C +G+ G  C        C  
Sbjct: 1079 KGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGP 1138

Query: 1082 HGQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRV---------DNDGRWECKCF-- 1129
               C  NG+C   +G  G       CP S  G  +C+            DG  +  C   
Sbjct: 1139 PSPCLYNGSCSETTGLGGPGFRC-SCPHSSPG-PRCQKPGAKGCEGRSGDGACDAGCSGP 1196

Query: 1130 -DGWDGPDCT 1138
               WDG DC+
Sbjct: 1197 GGNWDGGDCS 1206



 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 84/308 (27%), Positives = 116/308 (37%), Gaps = 62/308 (20%)

Query: 922  GECQCNPGWKGKECSLRHDECEVPD-CNGHGHCV------------------NGKCSCVR 962
            G CQC PG+ G+ C    D C+    C   G C                   +  C+C+ 
Sbjct: 51   GTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 109

Query: 963  GYKGKFCG---EIDCPHPTCSGHGFC-IEGT----CVCKKGWKGADCGTMDKDALQCLPD 1014
            G+ G+ C    E  CP   CS  G C I+ +    C C  GW G  C    +D     P 
Sbjct: 110  GFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL--RDFCSANPC 167

Query: 1015 CSGHGTFDVDTQT-CSCHAKWSGEDCSKEV--CSLECGP-------HGRCVGESCSCAAG 1064
             +G        Q  C C   + G  C ++V  C  + GP       H       C C  G
Sbjct: 168  VNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 227

Query: 1065 WSGEFCSVRL--CDAR-CAEHGQC-----KNGT---CLCVSGWNGRHCTL--EGC-PRSC 1110
              G  C +R   C  R C+  G C     K+ T   CLC  G+ G  C +  + C    C
Sbjct: 228  QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 287

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
               G C+ D    + C C + W G DC+       +D  + +  G   C +   CQ+ A 
Sbjct: 288  QNGGTCQ-DGLDTYTCLCPETWTGWDCS-------EDVDECEAQGPPHCRNGGTCQNSAG 339

Query: 1171 KSSQLCVS 1178
                +CVS
Sbjct: 340  SFHCVCVS 347



 Score = 77.4 bits (182), Expect = 7e-13
 Identities = 81/302 (26%), Positives = 110/302 (36%), Gaps = 59/302 (19%)

Query: 893  CQCQPGFGG-------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKECSLRHDECE 943
            C C  G+ G       D C++  CP    C Q G   +  C C  GW G  C+L    C+
Sbjct: 832  CLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFH--CLCLQGWTGPLCNLPLSSCQ 889

Query: 944  VPD----------CNGHGHCVNGK----CSCVRGYKGKFCGEI--DCPHPTCSGHGFCIE 987
                         C+  G CV+      C C  G++G  C +    C    C     C+ 
Sbjct: 890  KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMA 949

Query: 988  GT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT--CSCHAKWSGEDCSK 1041
                  C C  G+ G +C + + DA Q  P C  HGT         C+C   + G  C  
Sbjct: 950  QPSGYLCQCAPGYDGQNC-SKELDACQSQP-CHNHGTCTPKPGGFHCACPPGFVGLRCEG 1007

Query: 1042 EV--C-SLECGPHGRCVGES------CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT- 1089
            +V  C    C P G     S      C C  G +G++C V +  C ++   HG     T 
Sbjct: 1008 DVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATA 1067

Query: 1090 -------CLCVSGWNGRHCT--LEGCP-RSCAGHGQCRVDNDGRW--ECKCFDGWDGPDC 1137
                   C C  G+ G  C+     C    C   G C       +   C C  G+ GPDC
Sbjct: 1068 GSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDC 1127

Query: 1138 TT 1139
             T
Sbjct: 1128 LT 1129



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 86/311 (27%), Positives = 110/311 (35%), Gaps = 56/311 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ------------ 925
            CP G S         C C  G  G  C     P  C  RG    G CQ            
Sbjct: 207  CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP--CPPRGCSNGGTCQLMPEKDSTFHLC 264

Query: 926  -CNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP--- 975
             C PG+ G +C +  D C    C   G C +G     C C   + G  C E +D C    
Sbjct: 265  LCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQG 324

Query: 976  HPTCSGHGFCIEGT----CVCKKGWKGADC--GTMDKDALQCLPDCSGHGTFD-VDTQTC 1028
             P C   G C        CVC  GW G  C     D  A  C P   G    D V + +C
Sbjct: 325  PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAP---GSTCIDRVGSFSC 381

Query: 1029 SCHAKWSGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFCSVRLCDARCA 1080
             C    +G  C  +++C S  C    +C      G + C C  G+SG  C   L +   A
Sbjct: 382  LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 441

Query: 1081 EHG--QCKNG----------TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWEC 1126
            + G   C++G           CLC  G+ G  C  +   C       G   +D    + C
Sbjct: 442  QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 501

Query: 1127 KCFDGWDGPDC 1137
             C  G +G  C
Sbjct: 502  LCPPGLEGQLC 512



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 102/384 (26%), Positives = 137/384 (35%), Gaps = 74/384 (19%)

Query: 871  AEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--C-PVLCSQRGEYING 922
            +EEMT  C +G C   G C       +C C P   G  C  S   C    C   G  +N 
Sbjct: 729  SEEMTA-CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 787

Query: 923  ----ECQCNPGWKGKECSLR-HDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID 973
                 C C  G++G  C  +    C    C     C +     +C C  GY G  C  + 
Sbjct: 788  PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLM 847

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCG----TMDKDALQCLPDCSG---HGT 1020
              C    C  +  C++      C+C +GW G  C     +  K AL    D S    +G 
Sbjct: 848  DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 907

Query: 1021 FDVDTQT---CSCHAKWSGEDCSKEV--C-SLECGPHGRCV----GESCSCAAGWSGEFC 1070
              VD+     C C   + G  C   V  C S  C     C+    G  C CA G+ G+ C
Sbjct: 908  LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 967

Query: 1071 SVRL--CDAR-CAEHGQC--KNGT--CLCVSGWNGRHCT--LEGC---PRSCAGHGQCRV 1118
            S  L  C ++ C  HG C  K G   C C  G+ G  C   ++ C   P    G   C  
Sbjct: 968  SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACH- 1026

Query: 1119 DNDGRWECKCFDGWDGPDCTTLKEQI----------CDDSRDNDKDGLVDC----EDPEC 1164
                 + C+C  G  G  C    +            C+ +  +    +  C    E P C
Sbjct: 1027 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1086

Query: 1165 ------CQSPACKSSQLCVSSPKP 1182
                  C    C    LC+ SPKP
Sbjct: 1087 SHRAPSCGFHHCHHGGLCLPSPKP 1110



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 84/299 (28%), Positives = 108/299 (36%), Gaps = 58/299 (19%)

Query: 892  HCQCQPGFGG-------DDCSKSVC-PVLCSQRGEYING-ECQCNPGWKGKECSLRHDEC 942
            HC C PGF G       D+C    C P   +      N   CQC PG  G+ C +  D C
Sbjct: 993  HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPC 1052

Query: 943  EVPDCNGHGHC-------VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEGT---- 989
                C   G C       +   C C +G++G  C      C    C   G C+       
Sbjct: 1053 HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGF 1112

Query: 990  ---CVCKKGWKGADCGTMDKDALQCLPD--CSGHGTFDVDTQT------CSCHAKWSGED 1038
               C C  G+ G DC T       C P   C  +G+    T        CSC     G  
Sbjct: 1113 PPRCACLSGYGGPDCLTPPAPK-GCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPR 1171

Query: 1039 CSK---EVCSLECGPHGRCVGESCSCAAG-WSGEFCSVRLCDA--RCAEHGQC----KNG 1088
            C K   + C    G  G C    CS   G W G  CS+ + D    C  H +C    ++G
Sbjct: 1172 CQKPGAKGCEGRSGD-GAC-DAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDG 1229

Query: 1089 TCLCVSGWNGRHCTLEG--C--PRSCA-GHGQCRVDN--DGRWECKCFD---GWDGPDC 1137
             C      +   C  +G  C  P +C   + Q   D+  +G  E  C     GWDG DC
Sbjct: 1230 QCH--PQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDC 1286



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 70/263 (26%), Positives = 89/263 (33%), Gaps = 56/263 (21%)

Query: 892  HCQCQPGFGGDDCSKSVCPV---------LC-SQRGEYINGECQCNPGWKGKECSLRHDE 941
            +CQC PG  G  C   + P           C +  G  +   C C  G++G  CS R   
Sbjct: 1033 YCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS 1092

Query: 942  CEVPDCNGHGHCVNG-------KCSCVRGYKGKFC----GEIDCPHPT-CSGHGFCIEGT 989
            C    C+  G C+         +C+C+ GY G  C        C  P+ C  +G C E T
Sbjct: 1093 CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETT 1152

Query: 990  --------CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHA-KWSGEDCS 1040
                    C C     G  C    K   +     SG G  D     CS     W G DCS
Sbjct: 1153 GLGGPGFRCSCPHSSPGPRC---QKPGAKGCEGRSGDGACDAG---CSGPGGNWDGGDCS 1206

Query: 1041 KEVCS--LECGPHGRC--VGESCSCAAGWSGEFC--------SVRLC----DARCAEH-- 1082
              V      C  H RC  +     C      E C        +   C    D  C +H  
Sbjct: 1207 LGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFH 1266

Query: 1083 -GQCKNGTCLCVSGWNGRHCTLE 1104
             G C+ G      GW+G  C  E
Sbjct: 1267 NGHCEKGCNTAECGWDGGDCRPE 1289



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 44/165 (26%), Positives = 56/165 (33%), Gaps = 31/165 (18%)

Query: 874  MTHNCPNGCSGKGECLM-GHCQCQPGFGGD----DCSKSVCPVLCSQRG----EYINGEC 924
            +T   P GC     CL  G C    G GG      C  S     C + G    E  +G+ 
Sbjct: 1128 LTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDG 1187

Query: 925  QCNPGWKGKECSLRHDECE--VPD----CNGHGHCV----NGKCSCVRGYKGKFCGEIDC 974
             C+ G  G   +    +C   VPD    C  H  C     +G+C      +       DC
Sbjct: 1188 ACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDC 1247

Query: 975  PHPT---------CSGH---GFCIEGTCVCKKGWKGADCGTMDKD 1007
              P          C  H   G C +G    + GW G DC   D D
Sbjct: 1248 ETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGD 1292


>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
            translocation-associated (Drosophila) protein.
          Length = 2555

 Score =  118 bits (283), Expect = 4e-25
 Identities = 89/305 (29%), Positives = 128/305 (41%), Gaps = 40/305 (13%)

Query: 888  CLMGHCQCQPGFGGDDCSKSVCPV-LCSQRGEYING-ECQCNPGWKGKECSLRHDECEVP 945
            CL G          DDC+ S C    C  +   I+G EC C PG+ G  C++  DEC   
Sbjct: 629  CLKGTTGPNCEINLDDCASSPCDSGTCLDK---IDGYECACEPGYTGSMCNINIDECAGN 685

Query: 946  DCNGHGHC---VNG-KCSCVRGYKGKFC-GEI-DCPHPTCSGHGFCIEG----TCVCKKG 995
             C+  G C   +NG  C C  GY    C  E+ +C    C  HG C +      C C  G
Sbjct: 686  PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV-HGACRDSLNGYKCDCDPG 744

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPH 1051
            W G +C  ++ +  +  P  +G    D+ +   C+C   +SG +C     E  S  C   
Sbjct: 745  WSGTNC-DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQ 803

Query: 1052 GRCV----GESCSCAAGWSGEFCSVRL---CDARCAEHGQCKNG------TCLCVSGWNG 1098
            G C+    G  C+C   ++G  C V L     + C   G+C+        +C+C +GW G
Sbjct: 804  GTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQG 863

Query: 1099 RHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGL 1156
            + C ++   C  S   HG    +  G + C C  G+ G +C    E   DD R N     
Sbjct: 864  QTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNC----ETDIDDCRPNPCHNG 919

Query: 1157 VDCED 1161
              C D
Sbjct: 920  GSCTD 924



 Score =  111 bits (268), Expect = 3e-23
 Identities = 83/296 (28%), Positives = 123/296 (41%), Gaps = 42/296 (14%)

Query: 880  NGCSGKGECL--MGH--CQCQPGFGG-------DDCSKSVCPVLCSQRGEYINGECQCNP 928
            N C     CL  +G   C C PG+ G       D+C+ S C        +    +C+C  
Sbjct: 459  NPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPT 518

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EIDCPHPTCSGHG 983
            G+ G  C    DEC    C     C++G     C C  GY G  C  +ID   P    +G
Sbjct: 519  GFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG 578

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CSCHAKWSG 1036
             C +G    TC+C+ G+ G  C T   +  +C      HG    D      C C    +G
Sbjct: 579  SCKDGVATFTCLCRPGYTGHHCET---NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTG 635

Query: 1037 EDC--SKEVCSLECGPHGRCV----GESCSCAAGWSGEFCSVRLCDAR---CAEHGQCKN 1087
             +C  + + C+      G C+    G  C+C  G++G  C++ + +     C   G C++
Sbjct: 636  PNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCED 695

Query: 1088 G----TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G    TC C  G++   C  E   C  +   HG CR D+   ++C C  GW G +C
Sbjct: 696  GINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACR-DSLNGYKCDCDPGWSGTNC 750



 Score =  110 bits (264), Expect = 9e-23
 Identities = 100/346 (28%), Positives = 148/346 (42%), Gaps = 68/346 (19%)

Query: 878  CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGEYING----ECQCNP 928
            C NG  C   G+ +   C C PGF G +C +++  CP   C   G  ++G     C+C P
Sbjct: 227  CQNGGTCRPTGD-VTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPP 285

Query: 929  GWKGKECSLRHDECEV-PD-CNGHGHCVNG----KCSCVRGYKGKFCGEI--DCPHPTCS 980
             W G+ C+   DEC++ P+ C   G C N      C CV G+ G+ C E   DC    C 
Sbjct: 286  EWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACF 345

Query: 981  GHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-CSCHAKWS 1035
                C +      C C  G  G  C   D        + S   T  V+ +  C+C + ++
Sbjct: 346  HGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYT 405

Query: 1036 GEDCSKEV--CSLECGP--H-GRCVGE----SCSCAAGWSGEFCSVRL-------C--DA 1077
            G  CS++V  CSL   P  H G+C+       C C  G++G  C + +       C  DA
Sbjct: 406  GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDA 465

Query: 1078 RCAEHGQCKNGTCLCVSGWNGRHCTL--EGCPRS-CAGHGQCRVDNDGRWECKCFDGWDG 1134
             C +  Q     C+C+ G+ G HC +  + C  S C  +G+C +D    ++C+C  G+ G
Sbjct: 466  TCLD--QIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRC-LDKINEFQCECPTGFTG 522

Query: 1135 PDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSP 1180
              C              D D        EC  +P CK+   C+  P
Sbjct: 523  HLC------------QYDVD--------ECASTP-CKNGAKCLDGP 547



 Score =  107 bits (256), Expect = 8e-22
 Identities = 84/299 (28%), Positives = 117/299 (39%), Gaps = 44/299 (14%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSV--C---PVLCSQRGEYING-ECQCNPG 929
            N C   G C  G     C+C  G+    C   V  C   P +     + +NG +C C+PG
Sbjct: 685  NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 744

Query: 930  WKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPTCSGHG 983
            W G  C + ++ECE   C   G C    +G  C+C  G+ G  C     +C    C   G
Sbjct: 745  WSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQG 804

Query: 984  FCIEGT----CVCKKGWKGADCGTMDKDALQCLPD-CSGHG----TFDVDTQTCSCHAKW 1034
             CI+      C C   + GA C  +      C P  C   G    + D ++ +C C   W
Sbjct: 805  TCIDDVAGYKCNCLLPYTGATCEVV---LAPCAPSPCRNGGECRQSEDYESFSCVCPTGW 861

Query: 1035 SGEDCSKEV--CSLECGPHGRCV-----GESCSCAAGWSGEFCSVRLCDAR---CAEHGQ 1084
             G+ C  ++  C L    HG        G  C C AG+SG  C   + D R   C   G 
Sbjct: 862  QGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGS 921

Query: 1085 CKNGT----CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C +G     C C+ G+ G  C   +  C      +G    D    + C C  G+ G  C
Sbjct: 922  CTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHC 980



 Score =  105 bits (252), Expect = 2e-21
 Identities = 85/321 (26%), Positives = 122/321 (38%), Gaps = 54/321 (16%)

Query: 879  PNGCSGKGECLMGH------CQCQPGFGGDDCSKSV--CPVLCSQRG---EYING--ECQ 925
            P+ C   GEC          C C  G+ G  C   +  C +   + G   +  +G   C 
Sbjct: 835  PSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCH 894

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEI--DCPHPTC 979
            C  G+ G+ C    D+C    C+  G C +G     C C+ G++G FC E   +C    C
Sbjct: 895  CQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPC 954

Query: 980  SGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAK 1033
                 C +     TC C  G+ G  C     D  +    C   GT    +++ TC C   
Sbjct: 955  RNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTE--SSCFNGGTCVDGINSFTCLCPPG 1012

Query: 1034 WSGEDCSKEVCSLECGP--HG-----RCVGESCSCAAGWSGEFCS--VRLCDAR-CAEHG 1083
            ++G  C  +V   +  P  HG      C    C+C  G++G  C   V  CD+  C   G
Sbjct: 1013 FTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 1072

Query: 1084 QC----KNGTCLCVSGWNGRHCTLEGCPRSCAG------------HGQCRVDNDGRWECK 1127
            +C        C C SGW G +C +       A             HG   VD      C+
Sbjct: 1073 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCR 1132

Query: 1128 CFDGWDGPDCTTLKEQICDDS 1148
            C  G+ G  C  L ++ C  S
Sbjct: 1133 CQAGYTGSYCEDLVDE-CSPS 1152



 Score =  103 bits (248), Expect = 7e-21
 Identities = 88/311 (28%), Positives = 127/311 (40%), Gaps = 46/311 (14%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPV-LCSQRGEYING----ECQCNPGW 930
            C NG + K       C C+ GF G +C  ++  C    C  +G  I+     +C C   +
Sbjct: 762  CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY 821

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNGK------CSCVRGYKGKFCGEID---CPHPTCSG 981
             G  C +    C    C   G C   +      C C  G++G+ C E+D   C    C  
Sbjct: 822  TGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTC-EVDINECVLSPCR- 879

Query: 982  HGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPD-CSGHG--TFDVDTQTCSCHAK 1033
            HG   + T     C C+ G+ G +C T   D   C P+ C   G  T  ++T  C C   
Sbjct: 880  HGASCQNTHGGYRCHCQAGYSGRNCET---DIDDCRPNPCHNGGSCTDGINTAFCDCLPG 936

Query: 1034 WSGEDCSKEV--CSLE-CGPHGRCV----GESCSCAAGWSGEFCSVRLCD---ARCAEHG 1083
            + G  C +++  C+ + C     C       +C+C AG+SG  C     D   + C   G
Sbjct: 937  FRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG 996

Query: 1084 QCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +G    TCLC  G+ G +C   +  C      HG    D  G + C C  G+ GP+C
Sbjct: 997  TCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNC 1056

Query: 1138 TTLKEQICDDS 1148
              L    CD S
Sbjct: 1057 QNLVHW-CDSS 1066



 Score =  103 bits (248), Expect = 7e-21
 Identities = 99/340 (29%), Positives = 135/340 (39%), Gaps = 60/340 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKECSLRHDECEV 944
            HC+CQ G+ G  C   V  C     Q G    +Y+ G  C+C  G+ G  CS   DEC  
Sbjct: 1130 HCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLS 1189

Query: 945  PDCNGHGHCVN----GKCSCVRGYKGKFCGEI---DC--------PHPTCSGHGFCIEG- 988
              C   G C++     KCSC RG +G  C EI   DC          P C  +G C++  
Sbjct: 1190 HPCQNGGTCLDLPNTYKCSCPRGTQGVHC-EINVDDCNPPVDPVSRSPKCFNNGTCVDQV 1248

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD----VDTQTCSCHAKWSGEDCS 1040
               +C C  G+ G  C   + D  +CL + C   GT +    V+   C C A  +G  C 
Sbjct: 1249 GGYSCTCPPGFVGERC---EGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE 1305

Query: 1041 KEV--C-SLECGPHGRCV-------GESCSCAAGWSGEFC--SVRLCDA-RCAEHGQCKN 1087
              +  C    C   G C        G  C C AG+ G  C    R C + RC   G C +
Sbjct: 1306 SVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCIS 1365

Query: 1088 G----TCLCVSGWNGRHCTLEG---C--PRSCAGHGQCRVDNDGR-WECKCFDGWDGPDC 1137
            G    TCLC+  + G  C       C     C   G C   ++   + C C   ++G  C
Sbjct: 1366 GPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425

Query: 1138 TTLKEQICDDSRDNDKDGLVD--CEDPECCQSPACKSSQL 1175
              L       +  +    L++  CE PEC +    K   L
Sbjct: 1426 HILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSL 1465



 Score =  102 bits (245), Expect = 2e-20
 Identities = 86/295 (29%), Positives = 119/295 (40%), Gaps = 44/295 (14%)

Query: 882  CSGKGECLMGH----CQCQPGFGGDDCSKSV--C-PVLC---SQRGEYINGECQCNPGWK 931
            C    +CL G     C C  G+ G  C   +  C P  C   S +       C C PG+ 
Sbjct: 537  CKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYT 596

Query: 932  GKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEI---DCPHPTCSGHGF 984
            G  C    +EC    C   G C +      C C++G  G  C EI   DC    C   G 
Sbjct: 597  GHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC-EINLDDCASSPCDS-GT 654

Query: 985  C---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGED 1038
            C   I+G  C C+ G+ G+ C  ++ D     P C   GT +  ++  TC C   +    
Sbjct: 655  CLDKIDGYECACEPGYTGSMC-NINIDECAGNP-CHNGGTCEDGINGFTCRCPEGYHDPT 712

Query: 1039 CSKEVCSLECGP--HGRC----VGESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKNGT 1089
            C  EV      P  HG C     G  C C  GWSG  C +    C++  C   G CK+ T
Sbjct: 713  CLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMT 772

Query: 1090 ----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G +C   +  C  + C   G C +D+   ++C C   + G  C
Sbjct: 773  SGYVCTCREGFSGPNCQTNINECASNPCLNQGTC-IDDVAGYKCNCLLPYTGATC 826



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 94/358 (26%), Positives = 141/358 (39%), Gaps = 47/358 (13%)

Query: 874  MTHNCPNGCSGKGECLMGH-CQCQPGFGGDDCSKS--VCPVLCSQRGEYINGE----CQC 926
            +T+ C NG +     L  + C+C PG+ G  C ++       C+  G+ +  E    C C
Sbjct: 107  LTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHC 166

Query: 927  NPGWKGKECSLRHDEC-EVPD-CNGHGHCVNG----KCSCVRGYKGKFCGE--IDCPHPT 978
             P + G  C    +EC + P  C   G C N     +C C   + G  C    + C    
Sbjct: 167  PPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSP 226

Query: 979  CSGHGFC-----IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAK 1033
            C   G C     +   C C  G+ G +C     D         G     V+T  C C  +
Sbjct: 227  CQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPE 286

Query: 1034 WSGEDCSKEV--CSL---ECGPHGRC----VGESCSCAAGWSGEFCSVRLCD---ARCAE 1081
            W+G+ C+++V  C L    C   G C     G +C C  GW+GE CS  + D   A C  
Sbjct: 287  WTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFH 346

Query: 1082 HGQCKNGT----CLCVSGWNGRHCTL-EGC-PRSCAGHGQCRVDN-DGRWECKCFDGWDG 1134
               C +      C C  G  G  C L + C    C     C  +  +G+  C C  G+ G
Sbjct: 347  GATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTG 406

Query: 1135 PDCT------TLKEQICDDS-RDNDKDGLVDCEDPECCQSPACK-SSQLCVSSPKPTD 1184
            P C+      +L    C+ + +  +  G  +C+  +    P C+     CVS+P   D
Sbjct: 407  PACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQND 464



 Score = 94.7 bits (225), Expect = 5e-18
 Identities = 82/308 (26%), Positives = 116/308 (37%), Gaps = 51/308 (16%)

Query: 879  PNGCSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRGEYING-----ECQCN 927
            PN C   G C  G     C C PGF G  C + +  C     + G           C C 
Sbjct: 913  PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP 972

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE--IDCPHPTCSG 981
             G+ G  C     +C    C   G CV+G     C C  G+ G +C     +C    C  
Sbjct: 973  AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLH 1032

Query: 982  HGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSG 1036
             G C +G     C C +G+ G +C  +        P  +G   +   TQ  C C + W+G
Sbjct: 1033 GGTCQDGCGSYRCTCPQGYTGPNCQNL-VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTG 1091

Query: 1037 EDCSKEVCSLE-------------CGPHGRCVG----ESCSCAAGWSGEFCS--VRLCD- 1076
              C     S E             C   G CV       C C AG++G +C   V  C  
Sbjct: 1092 LYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSP 1151

Query: 1077 ARCAEHGQCKN----GTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCF 1129
            + C     C +     +C CV+G++G +C+  ++ C    C   G C +D    ++C C 
Sbjct: 1152 SPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC-LDLPNTYKCSCP 1210

Query: 1130 DGWDGPDC 1137
             G  G  C
Sbjct: 1211 RGTQGVHC 1218



 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 100/370 (27%), Positives = 146/370 (39%), Gaps = 84/370 (22%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGE----YINGECQCNPGW 930
            C +G + +  C    C C  G+ G +C   V  C    C   G+    +    C+C  GW
Sbjct: 1030 CLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW 1089

Query: 931  KGKECSLRHDECEVPD----------CNGHGHCVNG----KCSCVRGYKGKFCGEI--DC 974
             G  C +    CEV            C   G CV+      C C  GY G +C ++  +C
Sbjct: 1090 TGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDEC 1149

Query: 975  PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGT-FDV-DTQT 1027
                C     C +     +C C  G+ G +C    ++  +CL   C   GT  D+ +T  
Sbjct: 1150 SPSPCQNGATCTDYLGGYSCKCVAGYHGVNCS---EEIDECLSHPCQNGGTCLDLPNTYK 1206

Query: 1028 CSC-------HAKWSGEDCSKEVC----SLECGPHGRCV----GESCSCAAGWSGEFCSV 1072
            CSC       H + + +DC+  V     S +C  +G CV    G SC+C  G+ GE C  
Sbjct: 1207 CSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEG 1266

Query: 1073 RL-------CDARCAEH--GQCKNGTCLCVSGWNGRHC--TLEGCP-RSCAGHGQCRV-D 1119
             +       CDAR  ++   +  +  C C +G  GR C   + GC  + C   G C V  
Sbjct: 1267 DVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVAS 1326

Query: 1120 NDGR-WECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCVS 1178
            N  R + CKC  G++G  C                       D   C S  C +   C+S
Sbjct: 1327 NTARGFICKCPAGFEGATCEN---------------------DARTCGSLRCLNGGTCIS 1365

Query: 1179 SPK-PTDILL 1187
             P+ PT + L
Sbjct: 1366 GPRSPTCLCL 1375



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 81/317 (25%), Positives = 111/317 (35%), Gaps = 59/317 (18%)

Query: 866  FVALVAEEMTHNC-PNGCSGKG--ECLMG----HCQCQPGFGGDDCSKSV--C---PV-- 911
            FV    E   + C  N C  +G   C+      HC+C+ G  G  C   +  C   P   
Sbjct: 1259 FVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN 1318

Query: 912  --LCSQRGEYINGE-CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGY 964
               C+       G  C+C  G++G  C      C    C   G C++G     C C+  +
Sbjct: 1319 GGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPF 1378

Query: 965  KGKFCGEIDCPHPTCSGHGFCIEGTC--VCKKGWKGADCGTMDKDALQCLPDCS--GHGT 1020
             G  C +     P   G+    +GTC    +  +    C       L  + D S  G   
Sbjct: 1379 TGPEC-QFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAG 1437

Query: 1021 FDVDTQTC--SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCD-- 1076
             D+       +C      ED   +VCSL+C  H          A GW G  CS+   D  
Sbjct: 1438 RDIPPPLIEEACELPECQEDAGNKVCSLQCNNH----------ACGWDGGDCSLNFNDPW 1487

Query: 1077 ARCAEHGQCKN--GTCLCVSGWNGRHCTLEG--CPRSCAGHGQCR--VD-------NDGR 1123
              C +  QC        C S  N   C  +G  C R+    GQC    D       +DG 
Sbjct: 1488 KNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRA---EGQCNPLYDQYCKDHFSDGH 1544

Query: 1124 WECKCFDG---WDGPDC 1137
             +  C      WDG DC
Sbjct: 1545 CDQGCNSAECEWDGLDC 1561



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 33/118 (27%), Positives = 50/118 (42%), Gaps = 16/118 (13%)

Query: 1079 CAEHGQCK--NGT--CLCVSGWNGRHCTLEG-CPRS-CAGHGQCRV-DNDG--RWECKCF 1129
            C   G+C+  NGT  C+C   + G  C     C  + C   G C V D  G   + C C 
Sbjct: 31   CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90

Query: 1130 DGWDGPDCTTLKEQIC--DDSRDNDKDGLVDCEDPECCQSP-----ACKSSQLCVSSP 1180
             G+ GP C T  +  C  +  R+     L+   + +C   P     +C+ +  C S+P
Sbjct: 91   LGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNP 148



 Score = 34.3 bits (75), Expect = 6.8
 Identities = 25/95 (26%), Positives = 34/95 (35%), Gaps = 14/95 (14%)

Query: 1057 ESCSCAAGWSGEFCS-VRLC-DARCAEHGQC----KNGT----CLCVSGWNGRHCTL--- 1103
            E+C C   + G  C     C    C   G C    + G     C C  G++G  C     
Sbjct: 44   EACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLD 103

Query: 1104 EGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C    C   G C +     ++C+C  GW G  C
Sbjct: 104  NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSC 138


>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
            translocation-associated (Drosophila) protein.
          Length = 2555

 Score =  118 bits (283), Expect = 4e-25
 Identities = 89/305 (29%), Positives = 128/305 (41%), Gaps = 40/305 (13%)

Query: 888  CLMGHCQCQPGFGGDDCSKSVCPV-LCSQRGEYING-ECQCNPGWKGKECSLRHDECEVP 945
            CL G          DDC+ S C    C  +   I+G EC C PG+ G  C++  DEC   
Sbjct: 629  CLKGTTGPNCEINLDDCASSPCDSGTCLDK---IDGYECACEPGYTGSMCNINIDECAGN 685

Query: 946  DCNGHGHC---VNG-KCSCVRGYKGKFC-GEI-DCPHPTCSGHGFCIEG----TCVCKKG 995
             C+  G C   +NG  C C  GY    C  E+ +C    C  HG C +      C C  G
Sbjct: 686  PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV-HGACRDSLNGYKCDCDPG 744

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPH 1051
            W G +C  ++ +  +  P  +G    D+ +   C+C   +SG +C     E  S  C   
Sbjct: 745  WSGTNC-DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQ 803

Query: 1052 GRCV----GESCSCAAGWSGEFCSVRL---CDARCAEHGQCKNG------TCLCVSGWNG 1098
            G C+    G  C+C   ++G  C V L     + C   G+C+        +C+C +GW G
Sbjct: 804  GTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQG 863

Query: 1099 RHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGL 1156
            + C ++   C  S   HG    +  G + C C  G+ G +C    E   DD R N     
Sbjct: 864  QTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNC----ETDIDDCRPNPCHNG 919

Query: 1157 VDCED 1161
              C D
Sbjct: 920  GSCTD 924



 Score =  111 bits (268), Expect = 3e-23
 Identities = 83/296 (28%), Positives = 123/296 (41%), Gaps = 42/296 (14%)

Query: 880  NGCSGKGECL--MGH--CQCQPGFGG-------DDCSKSVCPVLCSQRGEYINGECQCNP 928
            N C     CL  +G   C C PG+ G       D+C+ S C        +    +C+C  
Sbjct: 459  NPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPT 518

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EIDCPHPTCSGHG 983
            G+ G  C    DEC    C     C++G     C C  GY G  C  +ID   P    +G
Sbjct: 519  GFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG 578

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CSCHAKWSG 1036
             C +G    TC+C+ G+ G  C T   +  +C      HG    D      C C    +G
Sbjct: 579  SCKDGVATFTCLCRPGYTGHHCET---NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTG 635

Query: 1037 EDC--SKEVCSLECGPHGRCV----GESCSCAAGWSGEFCSVRLCDAR---CAEHGQCKN 1087
             +C  + + C+      G C+    G  C+C  G++G  C++ + +     C   G C++
Sbjct: 636  PNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCED 695

Query: 1088 G----TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G    TC C  G++   C  E   C  +   HG CR D+   ++C C  GW G +C
Sbjct: 696  GINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACR-DSLNGYKCDCDPGWSGTNC 750



 Score =  110 bits (264), Expect = 9e-23
 Identities = 100/346 (28%), Positives = 148/346 (42%), Gaps = 68/346 (19%)

Query: 878  CPNG--CSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGEYING----ECQCNP 928
            C NG  C   G+ +   C C PGF G +C +++  CP   C   G  ++G     C+C P
Sbjct: 227  CQNGGTCRPTGD-VTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPP 285

Query: 929  GWKGKECSLRHDECEV-PD-CNGHGHCVNG----KCSCVRGYKGKFCGEI--DCPHPTCS 980
             W G+ C+   DEC++ P+ C   G C N      C CV G+ G+ C E   DC    C 
Sbjct: 286  EWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACF 345

Query: 981  GHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-CSCHAKWS 1035
                C +      C C  G  G  C   D        + S   T  V+ +  C+C + ++
Sbjct: 346  HGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYT 405

Query: 1036 GEDCSKEV--CSLECGP--H-GRCVGE----SCSCAAGWSGEFCSVRL-------C--DA 1077
            G  CS++V  CSL   P  H G+C+       C C  G++G  C + +       C  DA
Sbjct: 406  GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDA 465

Query: 1078 RCAEHGQCKNGTCLCVSGWNGRHCTL--EGCPRS-CAGHGQCRVDNDGRWECKCFDGWDG 1134
             C +  Q     C+C+ G+ G HC +  + C  S C  +G+C +D    ++C+C  G+ G
Sbjct: 466  TCLD--QIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRC-LDKINEFQCECPTGFTG 522

Query: 1135 PDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSP 1180
              C              D D        EC  +P CK+   C+  P
Sbjct: 523  HLC------------QYDVD--------ECASTP-CKNGAKCLDGP 547



 Score =  107 bits (256), Expect = 8e-22
 Identities = 84/299 (28%), Positives = 117/299 (39%), Gaps = 44/299 (14%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSV--C---PVLCSQRGEYING-ECQCNPG 929
            N C   G C  G     C+C  G+    C   V  C   P +     + +NG +C C+PG
Sbjct: 685  NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 744

Query: 930  WKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPTCSGHG 983
            W G  C + ++ECE   C   G C    +G  C+C  G+ G  C     +C    C   G
Sbjct: 745  WSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQG 804

Query: 984  FCIEGT----CVCKKGWKGADCGTMDKDALQCLPD-CSGHG----TFDVDTQTCSCHAKW 1034
             CI+      C C   + GA C  +      C P  C   G    + D ++ +C C   W
Sbjct: 805  TCIDDVAGYKCNCLLPYTGATCEVV---LAPCAPSPCRNGGECRQSEDYESFSCVCPTGW 861

Query: 1035 SGEDCSKEV--CSLECGPHGRCV-----GESCSCAAGWSGEFCSVRLCDAR---CAEHGQ 1084
             G+ C  ++  C L    HG        G  C C AG+SG  C   + D R   C   G 
Sbjct: 862  QGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGS 921

Query: 1085 CKNGT----CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C +G     C C+ G+ G  C   +  C      +G    D    + C C  G+ G  C
Sbjct: 922  CTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHC 980



 Score =  105 bits (252), Expect = 2e-21
 Identities = 85/321 (26%), Positives = 122/321 (38%), Gaps = 54/321 (16%)

Query: 879  PNGCSGKGECLMGH------CQCQPGFGGDDCSKSV--CPVLCSQRG---EYING--ECQ 925
            P+ C   GEC          C C  G+ G  C   +  C +   + G   +  +G   C 
Sbjct: 835  PSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCH 894

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEI--DCPHPTC 979
            C  G+ G+ C    D+C    C+  G C +G     C C+ G++G FC E   +C    C
Sbjct: 895  CQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPC 954

Query: 980  SGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAK 1033
                 C +     TC C  G+ G  C     D  +    C   GT    +++ TC C   
Sbjct: 955  RNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTE--SSCFNGGTCVDGINSFTCLCPPG 1012

Query: 1034 WSGEDCSKEVCSLECGP--HG-----RCVGESCSCAAGWSGEFCS--VRLCDAR-CAEHG 1083
            ++G  C  +V   +  P  HG      C    C+C  G++G  C   V  CD+  C   G
Sbjct: 1013 FTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 1072

Query: 1084 QC----KNGTCLCVSGWNGRHCTLEGCPRSCAG------------HGQCRVDNDGRWECK 1127
            +C        C C SGW G +C +       A             HG   VD      C+
Sbjct: 1073 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCR 1132

Query: 1128 CFDGWDGPDCTTLKEQICDDS 1148
            C  G+ G  C  L ++ C  S
Sbjct: 1133 CQAGYTGSYCEDLVDE-CSPS 1152



 Score =  103 bits (248), Expect = 7e-21
 Identities = 88/311 (28%), Positives = 127/311 (40%), Gaps = 46/311 (14%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPV-LCSQRGEYING----ECQCNPGW 930
            C NG + K       C C+ GF G +C  ++  C    C  +G  I+     +C C   +
Sbjct: 762  CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY 821

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNGK------CSCVRGYKGKFCGEID---CPHPTCSG 981
             G  C +    C    C   G C   +      C C  G++G+ C E+D   C    C  
Sbjct: 822  TGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTC-EVDINECVLSPCR- 879

Query: 982  HGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPD-CSGHG--TFDVDTQTCSCHAK 1033
            HG   + T     C C+ G+ G +C T   D   C P+ C   G  T  ++T  C C   
Sbjct: 880  HGASCQNTHGGYRCHCQAGYSGRNCET---DIDDCRPNPCHNGGSCTDGINTAFCDCLPG 936

Query: 1034 WSGEDCSKEV--CSLE-CGPHGRCV----GESCSCAAGWSGEFCSVRLCD---ARCAEHG 1083
            + G  C +++  C+ + C     C       +C+C AG+SG  C     D   + C   G
Sbjct: 937  FRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG 996

Query: 1084 QCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +G    TCLC  G+ G +C   +  C      HG    D  G + C C  G+ GP+C
Sbjct: 997  TCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNC 1056

Query: 1138 TTLKEQICDDS 1148
              L    CD S
Sbjct: 1057 QNLVHW-CDSS 1066



 Score =  103 bits (248), Expect = 7e-21
 Identities = 99/340 (29%), Positives = 135/340 (39%), Gaps = 60/340 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKECSLRHDECEV 944
            HC+CQ G+ G  C   V  C     Q G    +Y+ G  C+C  G+ G  CS   DEC  
Sbjct: 1130 HCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLS 1189

Query: 945  PDCNGHGHCVN----GKCSCVRGYKGKFCGEI---DC--------PHPTCSGHGFCIEG- 988
              C   G C++     KCSC RG +G  C EI   DC          P C  +G C++  
Sbjct: 1190 HPCQNGGTCLDLPNTYKCSCPRGTQGVHC-EINVDDCNPPVDPVSRSPKCFNNGTCVDQV 1248

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD----VDTQTCSCHAKWSGEDCS 1040
               +C C  G+ G  C   + D  +CL + C   GT +    V+   C C A  +G  C 
Sbjct: 1249 GGYSCTCPPGFVGERC---EGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE 1305

Query: 1041 KEV--C-SLECGPHGRCV-------GESCSCAAGWSGEFC--SVRLCDA-RCAEHGQCKN 1087
              +  C    C   G C        G  C C AG+ G  C    R C + RC   G C +
Sbjct: 1306 SVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCIS 1365

Query: 1088 G----TCLCVSGWNGRHCTLEG---C--PRSCAGHGQCRVDNDGR-WECKCFDGWDGPDC 1137
            G    TCLC+  + G  C       C     C   G C   ++   + C C   ++G  C
Sbjct: 1366 GPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425

Query: 1138 TTLKEQICDDSRDNDKDGLVD--CEDPECCQSPACKSSQL 1175
              L       +  +    L++  CE PEC +    K   L
Sbjct: 1426 HILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSL 1465



 Score =  102 bits (245), Expect = 2e-20
 Identities = 86/295 (29%), Positives = 119/295 (40%), Gaps = 44/295 (14%)

Query: 882  CSGKGECLMGH----CQCQPGFGGDDCSKSV--C-PVLC---SQRGEYINGECQCNPGWK 931
            C    +CL G     C C  G+ G  C   +  C P  C   S +       C C PG+ 
Sbjct: 537  CKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYT 596

Query: 932  GKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEI---DCPHPTCSGHGF 984
            G  C    +EC    C   G C +      C C++G  G  C EI   DC    C   G 
Sbjct: 597  GHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC-EINLDDCASSPCDS-GT 654

Query: 985  C---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGED 1038
            C   I+G  C C+ G+ G+ C  ++ D     P C   GT +  ++  TC C   +    
Sbjct: 655  CLDKIDGYECACEPGYTGSMC-NINIDECAGNP-CHNGGTCEDGINGFTCRCPEGYHDPT 712

Query: 1039 CSKEVCSLECGP--HGRC----VGESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKNGT 1089
            C  EV      P  HG C     G  C C  GWSG  C +    C++  C   G CK+ T
Sbjct: 713  CLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMT 772

Query: 1090 ----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G +C   +  C  + C   G C +D+   ++C C   + G  C
Sbjct: 773  SGYVCTCREGFSGPNCQTNINECASNPCLNQGTC-IDDVAGYKCNCLLPYTGATC 826



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 94/358 (26%), Positives = 141/358 (39%), Gaps = 47/358 (13%)

Query: 874  MTHNCPNGCSGKGECLMGH-CQCQPGFGGDDCSKS--VCPVLCSQRGEYINGE----CQC 926
            +T+ C NG +     L  + C+C PG+ G  C ++       C+  G+ +  E    C C
Sbjct: 107  LTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHC 166

Query: 927  NPGWKGKECSLRHDEC-EVPD-CNGHGHCVNG----KCSCVRGYKGKFCGE--IDCPHPT 978
             P + G  C    +EC + P  C   G C N     +C C   + G  C    + C    
Sbjct: 167  PPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSP 226

Query: 979  CSGHGFC-----IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAK 1033
            C   G C     +   C C  G+ G +C     D         G     V+T  C C  +
Sbjct: 227  CQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPE 286

Query: 1034 WSGEDCSKEV--CSL---ECGPHGRC----VGESCSCAAGWSGEFCSVRLCD---ARCAE 1081
            W+G+ C+++V  C L    C   G C     G +C C  GW+GE CS  + D   A C  
Sbjct: 287  WTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFH 346

Query: 1082 HGQCKNGT----CLCVSGWNGRHCTL-EGC-PRSCAGHGQCRVDN-DGRWECKCFDGWDG 1134
               C +      C C  G  G  C L + C    C     C  +  +G+  C C  G+ G
Sbjct: 347  GATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTG 406

Query: 1135 PDCT------TLKEQICDDS-RDNDKDGLVDCEDPECCQSPACK-SSQLCVSSPKPTD 1184
            P C+      +L    C+ + +  +  G  +C+  +    P C+     CVS+P   D
Sbjct: 407  PACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQND 464



 Score = 94.7 bits (225), Expect = 5e-18
 Identities = 82/308 (26%), Positives = 116/308 (37%), Gaps = 51/308 (16%)

Query: 879  PNGCSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRGEYING-----ECQCN 927
            PN C   G C  G     C C PGF G  C + +  C     + G           C C 
Sbjct: 913  PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP 972

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE--IDCPHPTCSG 981
             G+ G  C     +C    C   G CV+G     C C  G+ G +C     +C    C  
Sbjct: 973  AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLH 1032

Query: 982  HGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSG 1036
             G C +G     C C +G+ G +C  +        P  +G   +   TQ  C C + W+G
Sbjct: 1033 GGTCQDGCGSYRCTCPQGYTGPNCQNL-VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTG 1091

Query: 1037 EDCSKEVCSLE-------------CGPHGRCVG----ESCSCAAGWSGEFCS--VRLCD- 1076
              C     S E             C   G CV       C C AG++G +C   V  C  
Sbjct: 1092 LYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSP 1151

Query: 1077 ARCAEHGQCKN----GTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCF 1129
            + C     C +     +C CV+G++G +C+  ++ C    C   G C +D    ++C C 
Sbjct: 1152 SPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC-LDLPNTYKCSCP 1210

Query: 1130 DGWDGPDC 1137
             G  G  C
Sbjct: 1211 RGTQGVHC 1218



 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 100/370 (27%), Positives = 146/370 (39%), Gaps = 84/370 (22%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGE----YINGECQCNPGW 930
            C +G + +  C    C C  G+ G +C   V  C    C   G+    +    C+C  GW
Sbjct: 1030 CLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW 1089

Query: 931  KGKECSLRHDECEVPD----------CNGHGHCVNG----KCSCVRGYKGKFCGEI--DC 974
             G  C +    CEV            C   G CV+      C C  GY G +C ++  +C
Sbjct: 1090 TGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDEC 1149

Query: 975  PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGT-FDV-DTQT 1027
                C     C +     +C C  G+ G +C    ++  +CL   C   GT  D+ +T  
Sbjct: 1150 SPSPCQNGATCTDYLGGYSCKCVAGYHGVNCS---EEIDECLSHPCQNGGTCLDLPNTYK 1206

Query: 1028 CSC-------HAKWSGEDCSKEVC----SLECGPHGRCV----GESCSCAAGWSGEFCSV 1072
            CSC       H + + +DC+  V     S +C  +G CV    G SC+C  G+ GE C  
Sbjct: 1207 CSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEG 1266

Query: 1073 RL-------CDARCAEH--GQCKNGTCLCVSGWNGRHC--TLEGCP-RSCAGHGQCRV-D 1119
             +       CDAR  ++   +  +  C C +G  GR C   + GC  + C   G C V  
Sbjct: 1267 DVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVAS 1326

Query: 1120 NDGR-WECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCVS 1178
            N  R + CKC  G++G  C                       D   C S  C +   C+S
Sbjct: 1327 NTARGFICKCPAGFEGATCEN---------------------DARTCGSLRCLNGGTCIS 1365

Query: 1179 SPK-PTDILL 1187
             P+ PT + L
Sbjct: 1366 GPRSPTCLCL 1375



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 81/317 (25%), Positives = 111/317 (35%), Gaps = 59/317 (18%)

Query: 866  FVALVAEEMTHNC-PNGCSGKG--ECLMG----HCQCQPGFGGDDCSKSV--C---PV-- 911
            FV    E   + C  N C  +G   C+      HC+C+ G  G  C   +  C   P   
Sbjct: 1259 FVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN 1318

Query: 912  --LCSQRGEYINGE-CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGY 964
               C+       G  C+C  G++G  C      C    C   G C++G     C C+  +
Sbjct: 1319 GGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPF 1378

Query: 965  KGKFCGEIDCPHPTCSGHGFCIEGTC--VCKKGWKGADCGTMDKDALQCLPDCS--GHGT 1020
             G  C +     P   G+    +GTC    +  +    C       L  + D S  G   
Sbjct: 1379 TGPEC-QFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAG 1437

Query: 1021 FDVDTQTC--SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCD-- 1076
             D+       +C      ED   +VCSL+C  H          A GW G  CS+   D  
Sbjct: 1438 RDIPPPLIEEACELPECQEDAGNKVCSLQCNNH----------ACGWDGGDCSLNFNDPW 1487

Query: 1077 ARCAEHGQCKN--GTCLCVSGWNGRHCTLEG--CPRSCAGHGQCR--VD-------NDGR 1123
              C +  QC        C S  N   C  +G  C R+    GQC    D       +DG 
Sbjct: 1488 KNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRA---EGQCNPLYDQYCKDHFSDGH 1544

Query: 1124 WECKCFDG---WDGPDC 1137
             +  C      WDG DC
Sbjct: 1545 CDQGCNSAECEWDGLDC 1561



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 33/118 (27%), Positives = 50/118 (42%), Gaps = 16/118 (13%)

Query: 1079 CAEHGQCK--NGT--CLCVSGWNGRHCTLEG-CPRS-CAGHGQCRV-DNDG--RWECKCF 1129
            C   G+C+  NGT  C+C   + G  C     C  + C   G C V D  G   + C C 
Sbjct: 31   CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90

Query: 1130 DGWDGPDCTTLKEQIC--DDSRDNDKDGLVDCEDPECCQSP-----ACKSSQLCVSSP 1180
             G+ GP C T  +  C  +  R+     L+   + +C   P     +C+ +  C S+P
Sbjct: 91   LGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNP 148



 Score = 34.3 bits (75), Expect = 6.8
 Identities = 25/95 (26%), Positives = 34/95 (35%), Gaps = 14/95 (14%)

Query: 1057 ESCSCAAGWSGEFCS-VRLC-DARCAEHGQC----KNGT----CLCVSGWNGRHCTL--- 1103
            E+C C   + G  C     C    C   G C    + G     C C  G++G  C     
Sbjct: 44   EACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLD 103

Query: 1104 EGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C    C   G C +     ++C+C  GW G  C
Sbjct: 104  NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSC 138


>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein variant
            protein.
          Length = 2067

 Score =  118 bits (283), Expect = 4e-25
 Identities = 89/305 (29%), Positives = 128/305 (41%), Gaps = 40/305 (13%)

Query: 888  CLMGHCQCQPGFGGDDCSKSVCPV-LCSQRGEYING-ECQCNPGWKGKECSLRHDECEVP 945
            CL G          DDC+ S C    C  +   I+G EC C PG+ G  C++  DEC   
Sbjct: 141  CLKGTTGPNCEINLDDCASSPCDSGTCLDK---IDGYECACEPGYTGSMCNINIDECAGN 197

Query: 946  DCNGHGHC---VNG-KCSCVRGYKGKFC-GEI-DCPHPTCSGHGFCIEG----TCVCKKG 995
             C+  G C   +NG  C C  GY    C  E+ +C    C  HG C +      C C  G
Sbjct: 198  PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV-HGACRDSLNGYKCDCDPG 256

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDT-QTCSCHAKWSGEDCS---KEVCSLECGPH 1051
            W G +C  ++ +  +  P  +G    D+ +   C+C   +SG +C     E  S  C   
Sbjct: 257  WSGTNC-DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQ 315

Query: 1052 GRCV----GESCSCAAGWSGEFCSVRL---CDARCAEHGQCKNG------TCLCVSGWNG 1098
            G C+    G  C+C   ++G  C V L     + C   G+C+        +C+C +GW G
Sbjct: 316  GTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQG 375

Query: 1099 RHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGL 1156
            + C ++   C  S   HG    +  G + C C  G+ G +C    E   DD R N     
Sbjct: 376  QTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNC----ETDIDDCRPNPCHNG 431

Query: 1157 VDCED 1161
              C D
Sbjct: 432  GSCTD 436



 Score =  107 bits (256), Expect = 8e-22
 Identities = 84/299 (28%), Positives = 117/299 (39%), Gaps = 44/299 (14%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSV--C---PVLCSQRGEYING-ECQCNPG 929
            N C   G C  G     C+C  G+    C   V  C   P +     + +NG +C C+PG
Sbjct: 197  NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 256

Query: 930  WKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPTCSGHG 983
            W G  C + ++ECE   C   G C    +G  C+C  G+ G  C     +C    C   G
Sbjct: 257  WSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQG 316

Query: 984  FCIEGT----CVCKKGWKGADCGTMDKDALQCLPD-CSGHG----TFDVDTQTCSCHAKW 1034
             CI+      C C   + GA C  +      C P  C   G    + D ++ +C C   W
Sbjct: 317  TCIDDVAGYKCNCLLPYTGATCEVV---LAPCAPSPCRNGGECRQSEDYESFSCVCPTGW 373

Query: 1035 SGEDCSKEV--CSLECGPHGRCV-----GESCSCAAGWSGEFCSVRLCDAR---CAEHGQ 1084
             G+ C  ++  C L    HG        G  C C AG+SG  C   + D R   C   G 
Sbjct: 374  QGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGS 433

Query: 1085 CKNGT----CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C +G     C C+ G+ G  C   +  C      +G    D    + C C  G+ G  C
Sbjct: 434  CTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHC 492



 Score =  105 bits (252), Expect = 2e-21
 Identities = 85/321 (26%), Positives = 122/321 (38%), Gaps = 54/321 (16%)

Query: 879  PNGCSGKGECLMGH------CQCQPGFGGDDCSKSV--CPVLCSQRG---EYING--ECQ 925
            P+ C   GEC          C C  G+ G  C   +  C +   + G   +  +G   C 
Sbjct: 347  PSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCH 406

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEI--DCPHPTC 979
            C  G+ G+ C    D+C    C+  G C +G     C C+ G++G FC E   +C    C
Sbjct: 407  CQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPC 466

Query: 980  SGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAK 1033
                 C +     TC C  G+ G  C     D  +    C   GT    +++ TC C   
Sbjct: 467  RNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTE--SSCFNGGTCVDGINSFTCLCPPG 524

Query: 1034 WSGEDCSKEVCSLECGP--HG-----RCVGESCSCAAGWSGEFCS--VRLCDAR-CAEHG 1083
            ++G  C  +V   +  P  HG      C    C+C  G++G  C   V  CD+  C   G
Sbjct: 525  FTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 584

Query: 1084 QC----KNGTCLCVSGWNGRHCTLEGCPRSCAG------------HGQCRVDNDGRWECK 1127
            +C        C C SGW G +C +       A             HG   VD      C+
Sbjct: 585  KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCR 644

Query: 1128 CFDGWDGPDCTTLKEQICDDS 1148
            C  G+ G  C  L ++ C  S
Sbjct: 645  CQAGYTGSYCEDLVDE-CSPS 664



 Score =  105 bits (251), Expect = 3e-21
 Identities = 73/263 (27%), Positives = 111/263 (42%), Gaps = 31/263 (11%)

Query: 902  DDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----K 957
            D+C+ S C        +    +C+C  G+ G  C    DEC    C     C++G     
Sbjct: 4    DECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYT 63

Query: 958  CSCVRGYKGKFCG-EIDCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCL 1012
            C C  GY G  C  +ID   P    +G C +G    TC+C+ G+ G  C T   +  +C 
Sbjct: 64   CVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCET---NINECS 120

Query: 1013 PDCSGHGTFDVDTQT---CSCHAKWSGEDC--SKEVCSLECGPHGRCV----GESCSCAA 1063
                 HG    D      C C    +G +C  + + C+      G C+    G  C+C  
Sbjct: 121  SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEP 180

Query: 1064 GWSGEFCSVRLCDAR---CAEHGQCKNG----TCLCVSGWNGRHCTLE--GCPRSCAGHG 1114
            G++G  C++ + +     C   G C++G    TC C  G++   C  E   C  +   HG
Sbjct: 181  GYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHG 240

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
             CR D+   ++C C  GW G +C
Sbjct: 241  ACR-DSLNGYKCDCDPGWSGTNC 262



 Score =  103 bits (248), Expect = 7e-21
 Identities = 88/311 (28%), Positives = 127/311 (40%), Gaps = 46/311 (14%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPV-LCSQRGEYING----ECQCNPGW 930
            C NG + K       C C+ GF G +C  ++  C    C  +G  I+     +C C   +
Sbjct: 274  CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY 333

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNGK------CSCVRGYKGKFCGEID---CPHPTCSG 981
             G  C +    C    C   G C   +      C C  G++G+ C E+D   C    C  
Sbjct: 334  TGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTC-EVDINECVLSPCR- 391

Query: 982  HGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPD-CSGHG--TFDVDTQTCSCHAK 1033
            HG   + T     C C+ G+ G +C T   D   C P+ C   G  T  ++T  C C   
Sbjct: 392  HGASCQNTHGGYRCHCQAGYSGRNCET---DIDDCRPNPCHNGGSCTDGINTAFCDCLPG 448

Query: 1034 WSGEDCSKEV--CSLE-CGPHGRCV----GESCSCAAGWSGEFCSVRLCD---ARCAEHG 1083
            + G  C +++  C+ + C     C       +C+C AG+SG  C     D   + C   G
Sbjct: 449  FRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGG 508

Query: 1084 QCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +G    TCLC  G+ G +C   +  C      HG    D  G + C C  G+ GP+C
Sbjct: 509  TCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNC 568

Query: 1138 TTLKEQICDDS 1148
              L    CD S
Sbjct: 569  QNLVHW-CDSS 578



 Score =  103 bits (248), Expect = 7e-21
 Identities = 99/340 (29%), Positives = 135/340 (39%), Gaps = 60/340 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKECSLRHDECEV 944
            HC+CQ G+ G  C   V  C     Q G    +Y+ G  C+C  G+ G  CS   DEC  
Sbjct: 642  HCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLS 701

Query: 945  PDCNGHGHCVN----GKCSCVRGYKGKFCGEI---DC--------PHPTCSGHGFCIEG- 988
              C   G C++     KCSC RG +G  C EI   DC          P C  +G C++  
Sbjct: 702  HPCQNGGTCLDLPNTYKCSCPRGTQGVHC-EINVDDCNPPVDPVSRSPKCFNNGTCVDQV 760

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD----VDTQTCSCHAKWSGEDCS 1040
               +C C  G+ G  C   + D  +CL + C   GT +    V+   C C A  +G  C 
Sbjct: 761  GGYSCTCPPGFVGERC---EGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE 817

Query: 1041 KEV--C-SLECGPHGRCV-------GESCSCAAGWSGEFC--SVRLCDA-RCAEHGQCKN 1087
              +  C    C   G C        G  C C AG+ G  C    R C + RC   G C +
Sbjct: 818  SVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCIS 877

Query: 1088 G----TCLCVSGWNGRHCTLEG---C--PRSCAGHGQCRVDNDGR-WECKCFDGWDGPDC 1137
            G    TCLC+  + G  C       C     C   G C   ++   + C C   ++G  C
Sbjct: 878  GPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 937

Query: 1138 TTLKEQICDDSRDNDKDGLVD--CEDPECCQSPACKSSQL 1175
              L       +  +    L++  CE PEC +    K   L
Sbjct: 938  HILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSL 977



 Score =  102 bits (245), Expect = 2e-20
 Identities = 86/295 (29%), Positives = 119/295 (40%), Gaps = 44/295 (14%)

Query: 882  CSGKGECLMGH----CQCQPGFGGDDCSKSV--C-PVLC---SQRGEYINGECQCNPGWK 931
            C    +CL G     C C  G+ G  C   +  C P  C   S +       C C PG+ 
Sbjct: 49   CKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYT 108

Query: 932  GKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEI---DCPHPTCSGHGF 984
            G  C    +EC    C   G C +      C C++G  G  C EI   DC    C   G 
Sbjct: 109  GHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC-EINLDDCASSPCDS-GT 166

Query: 985  C---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGED 1038
            C   I+G  C C+ G+ G+ C  ++ D     P C   GT +  ++  TC C   +    
Sbjct: 167  CLDKIDGYECACEPGYTGSMC-NINIDECAGNP-CHNGGTCEDGINGFTCRCPEGYHDPT 224

Query: 1039 CSKEVCSLECGP--HGRC----VGESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKNGT 1089
            C  EV      P  HG C     G  C C  GWSG  C +    C++  C   G CK+ T
Sbjct: 225  CLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMT 284

Query: 1090 ----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G +C   +  C  + C   G C +D+   ++C C   + G  C
Sbjct: 285  SGYVCTCREGFSGPNCQTNINECASNPCLNQGTC-IDDVAGYKCNCLLPYTGATC 338



 Score = 94.7 bits (225), Expect = 5e-18
 Identities = 82/308 (26%), Positives = 116/308 (37%), Gaps = 51/308 (16%)

Query: 879  PNGCSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRGEYING-----ECQCN 927
            PN C   G C  G     C C PGF G  C + +  C     + G           C C 
Sbjct: 425  PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP 484

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE--IDCPHPTCSG 981
             G+ G  C     +C    C   G CV+G     C C  G+ G +C     +C    C  
Sbjct: 485  AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLH 544

Query: 982  HGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSG 1036
             G C +G     C C +G+ G +C  +        P  +G   +   TQ  C C + W+G
Sbjct: 545  GGTCQDGCGSYRCTCPQGYTGPNCQNL-VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTG 603

Query: 1037 EDCSKEVCSLE-------------CGPHGRCVG----ESCSCAAGWSGEFCS--VRLCD- 1076
              C     S E             C   G CV       C C AG++G +C   V  C  
Sbjct: 604  LYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSP 663

Query: 1077 ARCAEHGQCKN----GTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCF 1129
            + C     C +     +C CV+G++G +C+  ++ C    C   G C +D    ++C C 
Sbjct: 664  SPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC-LDLPNTYKCSCP 722

Query: 1130 DGWDGPDC 1137
             G  G  C
Sbjct: 723  RGTQGVHC 730



 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 100/370 (27%), Positives = 146/370 (39%), Gaps = 84/370 (22%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGE----YINGECQCNPGW 930
            C +G + +  C    C C  G+ G +C   V  C    C   G+    +    C+C  GW
Sbjct: 542  CLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW 601

Query: 931  KGKECSLRHDECEVPD----------CNGHGHCVNG----KCSCVRGYKGKFCGEI--DC 974
             G  C +    CEV            C   G CV+      C C  GY G +C ++  +C
Sbjct: 602  TGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDEC 661

Query: 975  PHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGT-FDV-DTQT 1027
                C     C +     +C C  G+ G +C    ++  +CL   C   GT  D+ +T  
Sbjct: 662  SPSPCQNGATCTDYLGGYSCKCVAGYHGVNCS---EEIDECLSHPCQNGGTCLDLPNTYK 718

Query: 1028 CSC-------HAKWSGEDCSKEVC----SLECGPHGRCV----GESCSCAAGWSGEFCSV 1072
            CSC       H + + +DC+  V     S +C  +G CV    G SC+C  G+ GE C  
Sbjct: 719  CSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEG 778

Query: 1073 RL-------CDARCAEH--GQCKNGTCLCVSGWNGRHC--TLEGCP-RSCAGHGQCRV-D 1119
             +       CDAR  ++   +  +  C C +G  GR C   + GC  + C   G C V  
Sbjct: 779  DVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVAS 838

Query: 1120 NDGR-WECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCVS 1178
            N  R + CKC  G++G  C                       D   C S  C +   C+S
Sbjct: 839  NTARGFICKCPAGFEGATCEN---------------------DARTCGSLRCLNGGTCIS 877

Query: 1179 SPK-PTDILL 1187
             P+ PT + L
Sbjct: 878  GPRSPTCLCL 887



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 81/317 (25%), Positives = 111/317 (35%), Gaps = 59/317 (18%)

Query: 866  FVALVAEEMTHNC-PNGCSGKG--ECLMG----HCQCQPGFGGDDCSKSV--C---PV-- 911
            FV    E   + C  N C  +G   C+      HC+C+ G  G  C   +  C   P   
Sbjct: 771  FVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN 830

Query: 912  --LCSQRGEYINGE-CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGY 964
               C+       G  C+C  G++G  C      C    C   G C++G     C C+  +
Sbjct: 831  GGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPF 890

Query: 965  KGKFCGEIDCPHPTCSGHGFCIEGTC--VCKKGWKGADCGTMDKDALQCLPDCS--GHGT 1020
             G  C +     P   G+    +GTC    +  +    C       L  + D S  G   
Sbjct: 891  TGPEC-QFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAG 949

Query: 1021 FDVDTQTC--SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCD-- 1076
             D+       +C      ED   +VCSL+C  H          A GW G  CS+   D  
Sbjct: 950  RDIPPPLIEEACELPECQEDAGNKVCSLQCNNH----------ACGWDGGDCSLNFNDPW 999

Query: 1077 ARCAEHGQCKN--GTCLCVSGWNGRHCTLEG--CPRSCAGHGQCR--VD-------NDGR 1123
              C +  QC        C S  N   C  +G  C R+    GQC    D       +DG 
Sbjct: 1000 KNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRA---EGQCNPLYDQYCKDHFSDGH 1056

Query: 1124 WECKCFDG---WDGPDC 1137
             +  C      WDG DC
Sbjct: 1057 CDQGCNSAECEWDGLDC 1073


>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
            protein.
          Length = 1289

 Score =  116 bits (279), Expect = 1e-24
 Identities = 100/356 (28%), Positives = 136/356 (38%), Gaps = 52/356 (14%)

Query: 872  EEMTHNCPNG-CSGKGECL--MGH--CQCQPGFGG-------DDCSKSVCPV--LCSQRG 917
            E   + C +G C  +  CL  +G   C C  GF G       D+C  S C    +C  R 
Sbjct: 432  ETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDR- 490

Query: 918  EYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-E 971
              +NG  C C  G+ G  C L  DEC    C     CV+     +C C  G++G  C   
Sbjct: 491  --VNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRN 548

Query: 972  IDCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQ 1026
            +D   P    HG C++G    +C C  G+ G  C +   D  +  P   G    D VD  
Sbjct: 549  VDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCES-QVDECRSQPCRHGGKCLDLVDKY 607

Query: 1027 TCSCHAKWSGEDCSKEV--CSLECGPHGRCVG----ESCSCAAGWSGEFCSVRL---CDA 1077
             C C +  +G +C   +  C+      G C        C C  G++G  C+V +     +
Sbjct: 608  LCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASS 667

Query: 1078 RCAEHGQCKNG----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDG 1131
             C E G C +G     CLC  G     C      C      HG C  D  G + C C  G
Sbjct: 668  PCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC-YDAPGGFRCVCEPG 726

Query: 1132 WDGPDCT------TLKEQICDDSRDNDKDGL-VDCEDPECCQSPACKSSQLCVSSP 1180
            W GP C+        + Q C        DG+   C  P   Q   C+    C  +P
Sbjct: 727  WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP 782



 Score =  113 bits (273), Expect = 7e-24
 Identities = 96/317 (30%), Positives = 129/317 (40%), Gaps = 58/317 (18%)

Query: 872  EEMTHNCPNGCSGKGECLMG--------HCQCQPGFGGDDCS------KSVCP--VLCS- 914
            E+  H+ P  C+G+G C            C+C  GF G DCS       S C     CS 
Sbjct: 82   EDPCHSGP--CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSV 139

Query: 915  -QRGEYINGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVNG----KCSCVRGYKGKF 968
               G ++   C C PG++G+ C    DEC V + C   G C+N     +C C  GY G  
Sbjct: 140  GPDGRFL---CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPL 196

Query: 969  CGE--IDCPHPTCSGHGFCIEG-----TCVCKKGWKGADC--GTMDKDALQCLPDCSGHG 1019
            C    + C    C   G C +       C C  G++G +C     D    +CL    G  
Sbjct: 197  CENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLN--GGTC 254

Query: 1020 TFDVDTQTCSCHAKWSGEDCSKEV--CSLE---CGPHGRCV----GESCSCAAGWSGEFC 1070
               V+T  C C  +W+G+ C+++V  C L+   C   G C     G SC C  GW+GE C
Sbjct: 255  VDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESC 314

Query: 1071 SVRLCD---ARCAEHGQCKNGT----CLCVSGWNGRHCTLEGCPRSCAGHGQCRVDN--- 1120
            S  + D   A C     C +      C C  G  G  C L+    S   H     D    
Sbjct: 315  SQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPV 374

Query: 1121 DGRWECKCFDGWDGPDC 1137
            +GR  C C  G+ G  C
Sbjct: 375  NGRAICTCPPGFTGGAC 391



 Score =  106 bits (255), Expect = 1e-21
 Identities = 89/290 (30%), Positives = 121/290 (41%), Gaps = 46/290 (15%)

Query: 893  CQCQPGFGGDDCSKSV--CPV--LCSQRGEYING----ECQCNPGWKGKECSLRHDECEV 944
            C C PG+ G  C   V  C V   C   G  +N      CQC  G+ G  C      C  
Sbjct: 147  CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAP 206

Query: 945  PDCNGHGHC-----VNGKCSCVRGYKGKFCGEI---DCPHPTCSGHGFCIEGT----CVC 992
              C   G C     +   C+C+ G++G+ C E+   DCP   C   G C++G     C C
Sbjct: 207  SPCRNGGTCRQSGDLTYDCACLPGFEGQNC-EVNVDDCPGHRCLNGGTCVDGVNTYNCQC 265

Query: 993  KKGWKGADCGTMDKDALQCLPD-CSGHGT-FD-VDTQTCSCHAKWSGEDCSKEV--CSLE 1047
               W G  C T D D  Q  P+ C   GT F+ +   +C C   W+GE CS+ +  C+  
Sbjct: 266  PPEWTGQFC-TEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATA 324

Query: 1048 CGPHG-----RCVGESCSCAAGWSGEFCSVR-LCDAR-CAEHGQCK----NGT--CLCVS 1094
               HG     R     C+C  G +G  C +   C +  C E   C     NG   C C  
Sbjct: 325  VCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPP 384

Query: 1095 GWNGRHCT--LEGCP---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            G+ G  C   ++ C      C   G+C V+  G + C+C  G+ GP C T
Sbjct: 385  GFTGGACDQDVDECSIGANPCEHLGRC-VNTQGSFLCQCGRGYTGPRCET 433



 Score =  103 bits (246), Expect = 1e-20
 Identities = 86/310 (27%), Positives = 119/310 (38%), Gaps = 46/310 (14%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG--------KCSCVRGYKGKFCGEID-C 974
            C C PGW G+ C L  D C    C G G C +          C C RG++G  C   D C
Sbjct: 68   CLCPPGWVGERCQL-EDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPC 126

Query: 975  PHPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ--- 1026
                C+    C  G      C C  G++G  C + D D  +    C  HG   ++T    
Sbjct: 127  LSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-DVDECRVGEPCR-HGGTCLNTPGSF 184

Query: 1027 TCSCHAKWSGEDCSKEV--CS-LECGPHGRC-----VGESCSCAAGWSGEFCSVRLCDA- 1077
             C C A ++G  C      C+   C   G C     +   C+C  G+ G+ C V + D  
Sbjct: 185  RCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCP 244

Query: 1078 --RCAEHGQCKNG----TCLCVSGWNGRHCT--LEGC---PRSCAGHGQCRVDNDGRWEC 1126
              RC   G C +G     C C   W G+ CT  ++ C   P +C   G C  +  G   C
Sbjct: 245  GHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTC-FNTLGGHSC 303

Query: 1127 KCFDGWDGPDCT----TLKEQIC-DDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSPK 1181
             C +GW G  C+         +C   +  +D+     C  P       C     CVS+P 
Sbjct: 304  VCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPC 363

Query: 1182 PTDILLRKQP 1191
              D +    P
Sbjct: 364  HEDAICDTNP 373



 Score =  101 bits (241), Expect = 5e-20
 Identities = 82/279 (29%), Positives = 112/279 (40%), Gaps = 49/279 (17%)

Query: 893  CQCQPGFGG-------DDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKECSLRHDECEV 944
            C+C  G  G       DDC+ + C     + G  IN  +C C PG+ G  C++  +EC  
Sbjct: 609  CRCPSGTTGVNCEVNIDDCASNPCTFGVCRDG--INRYDCVCQPGFTGPLCNVEINECAS 666

Query: 945  PDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIEG----TCVCKK 994
              C   G CV+G    +C C  G     C      C H  CS HG C +      CVC+ 
Sbjct: 667  SPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCS-HGICYDAPGGFRCVCEP 725

Query: 995  GWKGADCG-TMDKDALQCLPDCSGHGTFDVDTQ--TCSCHAKWSGEDCS-KEVCSLE-CG 1049
            GW G  C  ++ +DA +  P C   GT   D     C+C     G  C     C+   C 
Sbjct: 726  GWSGPRCSQSLARDACESQP-CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCE 784

Query: 1050 PHGRCVGES-----CSCAAGWSGEFCSVRLCDARCAEHGQCKNG----TCLCVSGWNGRH 1100
              GRC         CSC  GW             C   G C++G    +C C+ G+ G  
Sbjct: 785  HGGRCESAPGQLPVCSCPQGWQDP----------CLNGGSCQDGVGSFSCSCLPGFAGPR 834

Query: 1101 CT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C   ++ C  +  G G C  D+   + C C  G+ G  C
Sbjct: 835  CARDVDECLSNPCGPGTC-TDHVASFTCTCPPGYGGFHC 872



 Score = 98.3 bits (234), Expect = 4e-19
 Identities = 87/295 (29%), Positives = 111/295 (37%), Gaps = 42/295 (14%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVLCSQRGEYING----ECQCNPGWK 931
            C NG     +     C+C  GF G  C ++V  C       G  ++G     C C PG+ 
Sbjct: 519  CRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYT 578

Query: 932  GKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFCGEI---DCPHPTCSGHGF 984
            G  C  + DEC    C   G C++      C C  G  G  C E+   DC    C+  G 
Sbjct: 579  GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNC-EVNIDDCASNPCT-FGV 636

Query: 985  CIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CSCHAKWSGE 1037
            C +G     CVC+ G+ G  C     +  +C     G G   VD +    C C       
Sbjct: 637  CRDGINRYDCVCQPGFTGPLCNV---EINECASSPCGEGGSCVDGENGFRCLCPPGSLPP 693

Query: 1038 DC--SKEVCSLECGPHGRCV----GESCSCAAGWSGEFCSVRL----CDAR-CAEHGQCK 1086
             C      C+ E   HG C     G  C C  GWSG  CS  L    C+++ C   G C 
Sbjct: 694  LCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCS 753

Query: 1087 NG----TCLCVSGWNGRHC-TLEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGP 1135
            +      C C  G  GR C  L  C P  C   G+C         C C  GW  P
Sbjct: 754  SDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQDP 808



 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 93/319 (29%), Positives = 118/319 (36%), Gaps = 53/319 (16%)

Query: 877  NCPNG----CSGKGECLMG----HCQCQPGFGGDDCSKSVCPVLCSQRG------EYING 922
            +CP G    C   G C  G     C C PGF G  C++ V   L +  G         + 
Sbjct: 800  SCPQGWQDPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASF 859

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPH 976
             C C PG+ G  C     +C    C   G CV+G     C C  GY G  C  E D C  
Sbjct: 860  TCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLS 919

Query: 977  PTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHA 1032
              C   G C        C C + + G  C T+  D     P C   G        C C  
Sbjct: 920  RPCLHGGVCSAAHPGFRCTCLESFTGPQCQTL-VDWCSRQP-CQNGGRCVQTGAYCLCPP 977

Query: 1033 KWSGEDCS------KEVCS-----LE--CGPHGRCVGES----CSCAAGWSGEFC--SVR 1073
             WSG  C       +E  +     LE  C   G+CV E     C C  G +G  C   V 
Sbjct: 978  GWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVD 1037

Query: 1074 LCDARCAEHGQCKNG-----TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWEC 1126
             C A+  +HG    G      C C+ G+NG +C   ++ C      HG   +D   R+ C
Sbjct: 1038 PCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLC 1097

Query: 1127 KCFDGWDGPDCTTLKEQIC 1145
             C  G  G  C  + E  C
Sbjct: 1098 SCPPGTLGVLC-EINEDDC 1115



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 89/305 (29%), Positives = 125/305 (40%), Gaps = 53/305 (17%)

Query: 882  CSGKGECLM-----GHCQCQPGFGGDDCS-KSVC-PVLCSQRG----EYING----ECQC 926
            C+  G C         C C PG+ G+ C  +  C    C+ RG      + G     C+C
Sbjct: 52   CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 111

Query: 927  NPGWKGKECSLRHDECEVPDCNGHGHCVNGK-----CSCVRGYKGKFC-GEID-C-PHPT 978
              G++G +CSL  D C    C     C  G      CSC  GY+G+ C  ++D C     
Sbjct: 112  PRGFRGPDCSL-PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 170

Query: 979  CSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVD---TQTCSC 1030
            C   G C+   G+  C C  G+ G  C   +  A+ C P  C   GT       T  C+C
Sbjct: 171  CRHGGTCLNTPGSFRCQCPAGYTGPLC---ENPAVPCAPSPCRNGGTCRQSGDLTYDCAC 227

Query: 1031 HAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR--- 1078
               + G++C   V  C    C   G CV      +C C   W+G+FC+  V  C  +   
Sbjct: 228  LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNA 287

Query: 1079 CAEHGQCKN----GTCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
            C   G C N     +C+CV+GW G  C+  ++ C  +   HG    D    + C C  G 
Sbjct: 288  CHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGK 347

Query: 1133 DGPDC 1137
             G  C
Sbjct: 348  TGLLC 352



 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 85/321 (26%), Positives = 116/321 (36%), Gaps = 63/321 (19%)

Query: 879  PNGCSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---CSQRG----EYINGECQCN 927
            P+ C   G C+ G     C C+PG+ G  C     P L   C   G     +    C C 
Sbjct: 881  PSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCL 940

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVN--GKCSCVRGYKGKFCGEIDCP---------- 975
              + G +C    D C    C   G CV     C C  G+ G+ C     P          
Sbjct: 941  ESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGV 1000

Query: 976  --HPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD--VDTQ 1026
                 C   G C++      CVC +G  G+ C   +++   CL   C   GT    +   
Sbjct: 1001 RLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHC---EQEVDPCLAQPCQHGGTCRGYMGGY 1057

Query: 1027 TCSCHAKWSGEDCSKEV---CSLECGPHGRCVG----ESCSCAAGWSGEFCSVRLCDA-- 1077
             C C   ++G++C  +V    S  C   G C+       CSC  G  G  C +   D   
Sbjct: 1058 MCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGP 1117

Query: 1078 --------RCAEHGQCKNGT----CLCVSGWNGRHCT--LEGCPRSCAGHG----QCRVD 1119
                    RC  +G C +      C C  G+ G  C   +  C RS A H      C  D
Sbjct: 1118 GPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINEC-RSGACHAAHTRDCLQD 1176

Query: 1120 NDGRWECKCFDGWDGPDCTTL 1140
              G + C C  G+ GP C T+
Sbjct: 1177 PGGGFRCLCHAGFSGPRCQTV 1197



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 88/303 (29%), Positives = 118/303 (38%), Gaps = 51/303 (16%)

Query: 882  CSGKGECLMG----HCQCQPGFGGDDCSKSVCPVL---------CSQRGEYINGECQCNP 928
            C   G CL       CQC  G+ G  C     P           C Q G+ +  +C C P
Sbjct: 171  CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGD-LTYDCACLP 229

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP-HP-TCS 980
            G++G+ C +  D+C    C   G CV+G     C C   + G+FC E +D C   P  C 
Sbjct: 230  GFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACH 289

Query: 981  GHGFCIE----GTCVCKKGWKGADCGTMDKDALQ--CLPDCSGHGTFDVDTQTCSCHAKW 1034
              G C       +CVC  GW G  C     D     C    + H    V +  C+C    
Sbjct: 290  NGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDR--VASFYCACPMGK 347

Query: 1035 SGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFC--SVRLCD--ARCAEH 1082
            +G  C   + C S  C     C      G + C+C  G++G  C   V  C   A   EH
Sbjct: 348  TGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEH 407

Query: 1083 -GQCKN--GT--CLCVSGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
             G+C N  G+  C C  G+ G  C     E     C     C +D  G++ C C  G+ G
Sbjct: 408  LGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATC-LDRIGQFTCICMAGFTG 466

Query: 1135 PDC 1137
              C
Sbjct: 467  TYC 469



 Score = 79.0 bits (186), Expect = 2e-13
 Identities = 87/292 (29%), Positives = 113/292 (38%), Gaps = 58/292 (19%)

Query: 882  CSGKGECL----MGHCQCQPGFGGDDCSKSVCPVL---CSQRGE---YINGE-CQCNPGW 930
            C   G+C+      +C C  G  G  C + V P L   C   G    Y+ G  C+C PG+
Sbjct: 1006 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY 1065

Query: 931  KGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFC--GEIDC-PHPTCSGHG 983
             G  C    DEC    C   G C++      CSC  G  G  C   E DC P P      
Sbjct: 1066 NGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1125

Query: 984  FCI-EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
             C+  GTCV   G     C       L+C  D +       + ++ +CHA  +  DC ++
Sbjct: 1126 RCLHNGTCVDLVGGFRCTC-PPGYTGLRCEADIN-------ECRSGACHAAHT-RDCLQD 1176

Query: 1043 VCSLECGPHGRCVGESCSCAAGWSGEFCSVRL--CDARCAEH-GQCKNG---------TC 1090
                   P G   G  C C AG+SG  C   L  C+++  +H GQC+           TC
Sbjct: 1177 -------PGG---GFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTC 1226

Query: 1091 LCVSGWNGRHCTLEGCPRSCAGHGQCRV-----DNDGRWECKCFDGWDGPDC 1137
             C   + G  C  E   RSC    QC V            C C  G  GP C
Sbjct: 1227 HCAQPFWGPRC--ERVARSCR-ELQCPVGVPCQQTPRGPRCACPPGLSGPSC 1275



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 62/214 (28%), Positives = 84/214 (39%), Gaps = 28/214 (13%)

Query: 987  EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ------TCSCHAKWSGEDCS 1040
            E  C+C  GW G  C    +D     P C+G G             +C C   + G DCS
Sbjct: 65   EAACLCPPGWVGERCQL--EDPCHSGP-CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCS 121

Query: 1041 -KEVC-SLECGPHGRC-VGES----CSCAAGWSGEFCSVRLCDAR----CAEHGQCKN-- 1087
              + C S  C    RC VG      CSC  G+ G  C   + + R    C   G C N  
Sbjct: 122  LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTP 181

Query: 1088 GT--CLCVSGWNGRHC---TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
            G+  C C +G+ G  C    +   P  C   G CR   D  ++C C  G++G +C    +
Sbjct: 182  GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVD 241

Query: 1143 QICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
              C   R  +    VD  +   CQ P   + Q C
Sbjct: 242  D-CPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 274



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 37/109 (33%), Positives = 48/109 (44%), Gaps = 15/109 (13%)

Query: 1079 CAEHGQC-----KNGTCLCVSGWNGRHCTLEGCPRS--CAGHGQCR---VDNDGRWECKC 1128
            CA  G+C     +   CLC  GW G  C LE    S  CAG G C+   V    R+ C+C
Sbjct: 52   CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 111

Query: 1129 FDGWDGPDCT----TLKEQICDDSRDN-DKDGLVDCEDPECCQSPACKS 1172
              G+ GPDC+     L       +R +   DG   C  P   Q  +C+S
Sbjct: 112  PRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS 160


>AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar to
            mouse Jedi soluble isoform 736 protein protein.
          Length = 1037

 Score =  114 bits (274), Expect = 5e-24
 Identities = 96/333 (28%), Positives = 122/333 (36%), Gaps = 80/333 (24%)

Query: 882  CSGKGECLM--GHCQCQPGFGGDDCSKSVCP---------VLCSQRGEY------INGEC 924
            C+    C    G C C+ GF GD C+  +CP           C+   E+      +NGEC
Sbjct: 321  CAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGEC 380

Query: 925  QCNPGWKGKECSLR-HDECEVPDCNGHGHCV--------NGKCSCVRGYKGKFCGEIDCP 975
             C PGW G  C+     +   P C  H  C+        +G C C  GY G  C  + CP
Sbjct: 381  SCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL-CP 439

Query: 976  HPT----CSGHGFC--------IEGTCVCKKGWKGADCGTMDKD---ALQCLP--DCSGH 1018
              T    CS    C        I+G CVCK+GW+  +C            C     C+  
Sbjct: 440  PDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHE 499

Query: 1019 GTFDVDTQTCSCHAKWSGEDCS--------KEVCS--LECGPHGRC--VGESCSCAAGWS 1066
                  T  C+C   W G  C          E C+   +C     C  V   C C AGW 
Sbjct: 500  AVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWM 559

Query: 1067 GEFCSVRL--------CD--ARCAEHGQC--KNGTCLCVSGWNGRHCTL--------EGC 1106
            G  C +          C     C   G C  +NG C+C  G+ G  C          + C
Sbjct: 560  GARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRC 619

Query: 1107 -PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             P  CA H  C   N     C C  GW GPDC+
Sbjct: 620  VPCKCANHSFCHPSNG---TCYCLAGWTGPDCS 649



 Score =  100 bits (239), Expect = 9e-20
 Identities = 80/267 (29%), Positives = 110/267 (41%), Gaps = 59/267 (22%)

Query: 891  GHCQ--CQPGFGGDDCSKSV-CP--VLCSQRGEYINGECQCNPGWKGKECSLRHDECEVP 945
            G+C   C PG  G  C+ S  C    +CS +     G C C PGW G  C L   + +  
Sbjct: 475  GNCSVPCPPGTWGFSCNASCQCAHEAVCSPQ----TGACTCTPGWHGAHCQLPCPKGQFG 530

Query: 946  -------DCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHP----------TCSGHGFCI 986
                   DC+    C  V+G+C C  G+ G  C  + CP            TC   G C+
Sbjct: 531  EGCASRCDCDHSDGCDPVHGRCQCQAGWMGARC-HLSCPEGLWGVNCSNTCTCKNGGTCL 589

Query: 987  --EGTCVCKKGWKGADCGTM---DKDALQCLP-DCSGHGTFDVDTQTCSCHAKWSGEDCS 1040
               G CVC  G++G  C       +   +C+P  C+ H        TC C A W+G DCS
Sbjct: 590  PENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCS 649

Query: 1041 K--------EVCSLECGPH--GRCVGE--SCSCAAGWSG----EFCSVRLCDARCAEHGQ 1084
            +        E C+  C  H  G C  +  SC C  GW+G    E C +    A C++  Q
Sbjct: 650  QPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQ 709

Query: 1085 C--------KNGTCLCVSGWNGRHCTL 1103
            C        + G C+C  G +G  C +
Sbjct: 710  CGPGEKCHPETGACVCPPGHSGAPCRI 736



 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 97/339 (28%), Positives = 129/339 (38%), Gaps = 82/339 (24%)

Query: 878  CPNGCSGKGECLM-GHCQCQPGFGGDDCSKSVCPVL----------CSQRG--EYINGEC 924
            C   C   G C+    CQC PG+ GDDCS    P +          C      +  +G C
Sbjct: 105  CAQECV-HGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVC 163

Query: 925  QC-------------NPGWKGKECSLRHDECEVPDCNGH-GHC------VNGKC--SCVR 962
             C              PG+ G  C  R  +C    C+   G C          C  SC +
Sbjct: 164  SCPSGLQPPNCLQPCTPGYYGPACQFRC-QCHGAPCDPQTGACFCPAERTGPSCDVSCSQ 222

Query: 963  GYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDALQ---CLPDCSGH 1018
            G  G FC      H   +G  F   +G+C C  GW G  C     +      C  +C  H
Sbjct: 223  GTSGFFCPST---HSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCH 279

Query: 1019 --GTFDVDTQTCSCHAKWSGEDCSKEV--------CS--LECGPHGRC--VGESCSCAAG 1064
              G  D  T  C C   ++G+ C +E         C+   +C P  RC     +C C  G
Sbjct: 280  NGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHG 339

Query: 1065 WSGEFCSVRLC---------DARCA---EHG-QCK--NGTCLCVSGWNGRHCTLEGCPRS 1109
            ++G+ C+ RLC          A C    EH   C   NG C C+ GW G HC  E CP+ 
Sbjct: 340  FTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCN-ESCPQD 398

Query: 1110 CAGHG---QCRVDNDGRWE-----CKCFDGWDGPDCTTL 1140
              G G    C   + G  +     C+C  G+ GP C +L
Sbjct: 399  THGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL 437



 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 15/90 (16%)

Query: 1030 CHAKWSGEDCSKEVCSLECGPHGRCVGES-CSCAAGWSGEFCSVRL--------CD--AR 1078
            CH  +        +C+ EC  HGRCV  + C C  GW G+ CS           CD    
Sbjct: 91   CHGFYESRGFCVPLCAQEC-VHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCS 149

Query: 1079 CAEHGQC--KNGTCLCVSGWNGRHCTLEGC 1106
            C  +  C  K+G C C SG    +C L+ C
Sbjct: 150  CGNNSSCDPKSGVCSCPSGLQPPNC-LQPC 178



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 18/90 (20%)

Query: 1061 CAAGW--SGEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLE--------GC--P 1107
            C  G+  S  FC V LC   C  HG+C     C CV GW G  C+ E         C  P
Sbjct: 90   CCHGFYESRGFC-VPLCAQECV-HGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKP 147

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             SC  +  C   +     C C  G   P+C
Sbjct: 148  CSCGNNSSC---DPKSGVCSCPSGLQPPNC 174


>AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar to
            mouse Jedi soluble isoform 736 protein protein.
          Length = 1037

 Score =  114 bits (274), Expect = 5e-24
 Identities = 96/333 (28%), Positives = 122/333 (36%), Gaps = 80/333 (24%)

Query: 882  CSGKGECLM--GHCQCQPGFGGDDCSKSVCP---------VLCSQRGEY------INGEC 924
            C+    C    G C C+ GF GD C+  +CP           C+   E+      +NGEC
Sbjct: 321  CAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGEC 380

Query: 925  QCNPGWKGKECSLR-HDECEVPDCNGHGHCV--------NGKCSCVRGYKGKFCGEIDCP 975
             C PGW G  C+     +   P C  H  C+        +G C C  GY G  C  + CP
Sbjct: 381  SCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL-CP 439

Query: 976  HPT----CSGHGFC--------IEGTCVCKKGWKGADCGTMDKD---ALQCLP--DCSGH 1018
              T    CS    C        I+G CVCK+GW+  +C            C     C+  
Sbjct: 440  PDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHE 499

Query: 1019 GTFDVDTQTCSCHAKWSGEDCS--------KEVCS--LECGPHGRC--VGESCSCAAGWS 1066
                  T  C+C   W G  C          E C+   +C     C  V   C C AGW 
Sbjct: 500  AVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWM 559

Query: 1067 GEFCSVRL--------CD--ARCAEHGQC--KNGTCLCVSGWNGRHCTL--------EGC 1106
            G  C +          C     C   G C  +NG C+C  G+ G  C          + C
Sbjct: 560  GARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRC 619

Query: 1107 -PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             P  CA H  C   N     C C  GW GPDC+
Sbjct: 620  VPCKCANHSFCHPSNG---TCYCLAGWTGPDCS 649



 Score =  100 bits (239), Expect = 9e-20
 Identities = 80/267 (29%), Positives = 110/267 (41%), Gaps = 59/267 (22%)

Query: 891  GHCQ--CQPGFGGDDCSKSV-CP--VLCSQRGEYINGECQCNPGWKGKECSLRHDECEVP 945
            G+C   C PG  G  C+ S  C    +CS +     G C C PGW G  C L   + +  
Sbjct: 475  GNCSVPCPPGTWGFSCNASCQCAHEAVCSPQ----TGACTCTPGWHGAHCQLPCPKGQFG 530

Query: 946  -------DCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHP----------TCSGHGFCI 986
                   DC+    C  V+G+C C  G+ G  C  + CP            TC   G C+
Sbjct: 531  EGCASRCDCDHSDGCDPVHGRCQCQAGWMGARC-HLSCPEGLWGVNCSNTCTCKNGGTCL 589

Query: 987  --EGTCVCKKGWKGADCGTM---DKDALQCLP-DCSGHGTFDVDTQTCSCHAKWSGEDCS 1040
               G CVC  G++G  C       +   +C+P  C+ H        TC C A W+G DCS
Sbjct: 590  PENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCS 649

Query: 1041 K--------EVCSLECGPH--GRCVGE--SCSCAAGWSG----EFCSVRLCDARCAEHGQ 1084
            +        E C+  C  H  G C  +  SC C  GW+G    E C +    A C++  Q
Sbjct: 650  QPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQ 709

Query: 1085 C--------KNGTCLCVSGWNGRHCTL 1103
            C        + G C+C  G +G  C +
Sbjct: 710  CGPGEKCHPETGACVCPPGHSGAPCRI 736



 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 97/339 (28%), Positives = 129/339 (38%), Gaps = 82/339 (24%)

Query: 878  CPNGCSGKGECLM-GHCQCQPGFGGDDCSKSVCPVL----------CSQRG--EYINGEC 924
            C   C   G C+    CQC PG+ GDDCS    P +          C      +  +G C
Sbjct: 105  CAQECV-HGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVC 163

Query: 925  QC-------------NPGWKGKECSLRHDECEVPDCNGH-GHC------VNGKC--SCVR 962
             C              PG+ G  C  R  +C    C+   G C          C  SC +
Sbjct: 164  SCPSGLQPPNCLQPCTPGYYGPACQFRC-QCHGAPCDPQTGACFCPAERTGPSCDVSCSQ 222

Query: 963  GYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDALQ---CLPDCSGH 1018
            G  G FC      H   +G  F   +G+C C  GW G  C     +      C  +C  H
Sbjct: 223  GTSGFFCPST---HSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCH 279

Query: 1019 --GTFDVDTQTCSCHAKWSGEDCSKEV--------CS--LECGPHGRC--VGESCSCAAG 1064
              G  D  T  C C   ++G+ C +E         C+   +C P  RC     +C C  G
Sbjct: 280  NGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHG 339

Query: 1065 WSGEFCSVRLC---------DARCA---EHG-QCK--NGTCLCVSGWNGRHCTLEGCPRS 1109
            ++G+ C+ RLC          A C    EH   C   NG C C+ GW G HC  E CP+ 
Sbjct: 340  FTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCN-ESCPQD 398

Query: 1110 CAGHG---QCRVDNDGRWE-----CKCFDGWDGPDCTTL 1140
              G G    C   + G  +     C+C  G+ GP C +L
Sbjct: 399  THGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL 437



 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 15/90 (16%)

Query: 1030 CHAKWSGEDCSKEVCSLECGPHGRCVGES-CSCAAGWSGEFCSVRL--------CD--AR 1078
            CH  +        +C+ EC  HGRCV  + C C  GW G+ CS           CD    
Sbjct: 91   CHGFYESRGFCVPLCAQEC-VHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCS 149

Query: 1079 CAEHGQC--KNGTCLCVSGWNGRHCTLEGC 1106
            C  +  C  K+G C C SG    +C L+ C
Sbjct: 150  CGNNSSCDPKSGVCSCPSGLQPPNC-LQPC 178



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 18/90 (20%)

Query: 1061 CAAGW--SGEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLE--------GC--P 1107
            C  G+  S  FC V LC   C  HG+C     C CV GW G  C+ E         C  P
Sbjct: 90   CCHGFYESRGFC-VPLCAQECV-HGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKP 147

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             SC  +  C   +     C C  G   P+C
Sbjct: 148  CSCGNNSSC---DPKSGVCSCPSGLQPPNC 174


>BC063815-1|AAH63815.1|  647|Homo sapiens NOTCH4 protein protein.
          Length = 647

 Score =  113 bits (271), Expect = 1e-23
 Identities = 93/320 (29%), Positives = 127/320 (39%), Gaps = 50/320 (15%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C----PVLCSQRGEYING----E 923
            ++H C NG + +       C C   + G DCS+ V  C    P  C   G   N      
Sbjct: 281  VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID-CPHPT 978
            C C  GW G  C    D+C    C     C++      C C  G  G  C   D C    
Sbjct: 341  CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 400

Query: 979  CSGHGFC----IEGT--CVCKKGWKGADCGTMDKDALQCL-----PDCSGHGTFDVDTQ- 1026
            C G   C    + G+  C+C+ G+ G  C    +D  +CL     P    HG   ++T  
Sbjct: 401  CHGDAQCSTNPLTGSTLCLCQPGYSGPTC---HQDLDECLMAQQGPSPCEHGGSCLNTPG 457

Query: 1027 --TCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL--- 1074
               C C   ++G  C     E  S  C P   C+       C C  G  G+ C V     
Sbjct: 458  SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC 517

Query: 1075 CDARCAEHGQCK---NG-TCLCVSGWNGRHCT--LEGCPRS-CAGHGQCRVDNDGRWECK 1127
              A C  H  C    NG  C+C+ G++G  C   ++ C  S CA  GQC+ D  G + CK
Sbjct: 518  ASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ-DQPGAFHCK 576

Query: 1128 CFDGWDGPDCTTLKEQICDD 1147
            C  G++GP C T  ++   D
Sbjct: 577  CLPGFEGPRCQTEVDECLSD 596



 Score =  105 bits (253), Expect = 2e-21
 Identities = 91/292 (31%), Positives = 120/292 (41%), Gaps = 51/292 (17%)

Query: 893  CQCQPGFGGDDCSKSV---CPV-LCSQRGE-YING----ECQCNPGWKGKECSLRHDECE 943
            C C PGF G+ C   +   CP   CS+RG  +I      +C C PGW G++C LR D C 
Sbjct: 103  CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCS 161

Query: 944  VPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDC---PHPTCSG---HGFCIEGTCV 991
               C   G C+      +C C  G++G  C     +C   P P   G   H       C+
Sbjct: 162  ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 221

Query: 992  CKKGWKGADCGTMDKDALQCLP-DCSGHGTF------DVDTQTCSCHAKWSGEDC--SKE 1042
            C  G +G  C   +  A  C P  CS  GT       D     C C   + G DC  + +
Sbjct: 222  CPVGQEGPRC---ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278

Query: 1043 VC-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR----CAEHGQCKNGT-- 1089
             C S +C   G C       +C C   W+G  CS  V  C+ +    C   G C+N    
Sbjct: 279  NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338

Query: 1090 --CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+CVSGW G  C   L+ C  +    G   +D  G + C C  G  G  C
Sbjct: 339  FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390



 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 84/308 (27%), Positives = 116/308 (37%), Gaps = 62/308 (20%)

Query: 922  GECQCNPGWKGKECSLRHDECEVPD-CNGHGHCV------------------NGKCSCVR 962
            G CQC PG+ G+ C    D C+    C   G C                   +  C+C+ 
Sbjct: 49   GTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 107

Query: 963  GYKGKFCG---EIDCPHPTCSGHGFC-IEGT----CVCKKGWKGADCGTMDKDALQCLPD 1014
            G+ G+ C    E  CP   CS  G C I+ +    C C  GW G  C    +D     P 
Sbjct: 108  GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL--RDFCSANPC 165

Query: 1015 CSGHGTFDVDTQT-CSCHAKWSGEDCSKEV--CSLECGP-------HGRCVGESCSCAAG 1064
             +G        Q  C C   + G  C ++V  C  + GP       H       C C  G
Sbjct: 166  VNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225

Query: 1065 WSGEFCSVRL--CDAR-CAEHGQC-----KNGT---CLCVSGWNGRHCTL--EGC-PRSC 1110
              G  C +R   C  R C+  G C     K+ T   CLC  G+ G  C +  + C    C
Sbjct: 226  QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
               G C+ D    + C C + W G DC+       +D  + +  G   C +   CQ+ A 
Sbjct: 286  QNGGTCQ-DGLDTYTCLCPETWTGWDCS-------EDVDECETQGPPHCRNGGTCQNSAG 337

Query: 1171 KSSQLCVS 1178
                +CVS
Sbjct: 338  SFHCVCVS 345



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 86/311 (27%), Positives = 110/311 (35%), Gaps = 56/311 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ------------ 925
            CP G S         C C  G  G  C     P  C  RG    G CQ            
Sbjct: 205  CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP--CPPRGCSNGGTCQLMPEKDSTFHLC 262

Query: 926  -CNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP--- 975
             C PG+ G +C +  D C    C   G C +G     C C   + G  C E +D C    
Sbjct: 263  LCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQG 322

Query: 976  HPTCSGHGFCIEGT----CVCKKGWKGADC--GTMDKDALQCLPDCSGHGTFD-VDTQTC 1028
             P C   G C        CVC  GW G  C     D  A  C P   G    D V + +C
Sbjct: 323  PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAP---GSTCIDRVGSFSC 379

Query: 1029 SCHAKWSGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFCSVRLCDARCA 1080
             C    +G  C  +++C S  C    +C      G + C C  G+SG  C   L +   A
Sbjct: 380  LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 439

Query: 1081 EHG--QCKNG----------TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWEC 1126
            + G   C++G           CLC  G+ G  C  +   C       G   +D    + C
Sbjct: 440  QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 499

Query: 1127 KCFDGWDGPDC 1137
             C  G +G  C
Sbjct: 500  LCPPGLEGQLC 510



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 16/113 (14%)

Query: 870 VAEEMTHNCPNG-CSGKGEC---LMG-HCQCQPGFGGDDCSKSV--CPVL-CSQRGEYIN 921
           + E  T+ C +  C    +C   L G  C C PGF G  C + +  C    C+  G+  +
Sbjct: 509 LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD 568

Query: 922 G----ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKG 966
                 C+C PG++G  C    DEC    C     C++  G   C C  G+ G
Sbjct: 569 QPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTG 621


>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
          Length = 2444

 Score =  111 bits (267), Expect = 4e-23
 Identities = 93/345 (26%), Positives = 139/345 (40%), Gaps = 48/345 (13%)

Query: 880  NGCSGKGECL--MGH--CQCQPGFGG-------DDCSKSVCPVLCSQRGEYINGECQCNP 928
            N C     CL  +G   C C PG+ G       D+C+ S C        +    +C+C  
Sbjct: 459  NPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPT 518

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EIDCPHPTCSGHG 983
            G+ G  C    DEC    C     C++G     C C  GY G  C  +ID   P    +G
Sbjct: 519  GFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG 578

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF-DVD-TQTCSCHAKWSGE 1037
             C +G    TC+C+ G+ G  C T   +       C   GT  D D    C C    +G 
Sbjct: 579  SCKDGVATFTCLCRPGYTGHHCETNINECSS--QPCRLRGTCQDPDNAYLCFCLKGTTGP 636

Query: 1038 DC--SKEVCSLECGPHGRCV----GESCSCAAGWSGEFCSVRLCDAR---CAEHGQCKNG 1088
            +C  + + C+      G C+    G  C+C  G++G  C+  + +     C   G C++G
Sbjct: 637  NCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNSNIDECAGNPCHNGGTCEDG 696

Query: 1089 ----TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
                TC C  G++   C  E   C  +   HG CR D+   ++C C  GW G +C  +  
Sbjct: 697  INGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACR-DSLNGYKCDCDPGWSGTNC-DINN 754

Query: 1143 QICDDS------RDNDKDGLVDCEDPECCQSPACKSS-QLCVSSP 1180
              C+ +         D    + C   E    P C+++   C S+P
Sbjct: 755  NECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNP 799



 Score =  106 bits (255), Expect = 1e-21
 Identities = 88/306 (28%), Positives = 126/306 (41%), Gaps = 41/306 (13%)

Query: 888  CLMGHCQCQPGFGGDDCSKSVCPV-LCSQRGEYING-ECQCNPGWKGKECSLRHDECEVP 945
            CL G          DDC+ S C    C  +   I+G EC C PG+ G  C+   DEC   
Sbjct: 629  CLKGTTGPNCEINLDDCASSPCDSGTCLDK---IDGYECACEPGYTGSMCNSNIDECAGN 685

Query: 946  DCNGHGHC---VNG-KCSCVRGYKGKFC-GEI-DCPHPTCSGHGFCIEG----TCVCKKG 995
             C+  G C   +NG  C C  GY    C  E+ +C    C  HG C +      C C  G
Sbjct: 686  PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV-HGACRDSLNGYKCDCDPG 744

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCS---KEVCSLECGPH 1051
            W G +C  ++ +  +  P  +G    D+ +   C+C   +SG +C     E  S  C   
Sbjct: 745  WSGTNC-DINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLNK 803

Query: 1052 GRCV----GESCSCAAGWSGEFCSVRL---CDARCAEHGQCKNG------TCLC-VSGWN 1097
            G C+    G  C+C   ++G  C V L     + C   G+C+        +C+C  +G  
Sbjct: 804  GTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGAK 863

Query: 1098 GRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG 1155
            G+ C ++   C  S   HG    +  G + C C  G+ G +C    E   DD R N    
Sbjct: 864  GQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNC----ETDIDDCRPNPCHN 919

Query: 1156 LVDCED 1161
               C D
Sbjct: 920  GGSCTD 925



 Score =  103 bits (248), Expect = 7e-21
 Identities = 99/340 (29%), Positives = 135/340 (39%), Gaps = 60/340 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKECSLRHDECEV 944
            HC+CQ G+ G  C   V  C     Q G    +Y+ G  C+C  G+ G  CS   DEC  
Sbjct: 1131 HCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLS 1190

Query: 945  PDCNGHGHCVN----GKCSCVRGYKGKFCGEI---DC--------PHPTCSGHGFCIEG- 988
              C   G C++     KCSC RG +G  C EI   DC          P C  +G C++  
Sbjct: 1191 HPCQNGGTCLDLPNTYKCSCPRGTQGVHC-EINVDDCNPPVDPVSRSPKCFNNGTCVDQV 1249

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD----VDTQTCSCHAKWSGEDCS 1040
               +C C  G+ G  C   + D  +CL + C   GT +    V+   C C A  +G  C 
Sbjct: 1250 GGYSCTCPPGFVGERC---EGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE 1306

Query: 1041 KEV--C-SLECGPHGRCV-------GESCSCAAGWSGEFC--SVRLCDA-RCAEHGQCKN 1087
              +  C    C   G C        G  C C AG+ G  C    R C + RC   G C +
Sbjct: 1307 SVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCIS 1366

Query: 1088 G----TCLCVSGWNGRHCTLEG---C--PRSCAGHGQCRVDNDGR-WECKCFDGWDGPDC 1137
            G    TCLC+  + G  C       C     C   G C   ++   + C C   ++G  C
Sbjct: 1367 GPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1426

Query: 1138 TTLKEQICDDSRDNDKDGLVD--CEDPECCQSPACKSSQL 1175
              L       +  +    L++  CE PEC +    K   L
Sbjct: 1427 HILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSL 1466



 Score =  102 bits (244), Expect = 2e-20
 Identities = 86/295 (29%), Positives = 119/295 (40%), Gaps = 44/295 (14%)

Query: 882  CSGKGECLMGH----CQCQPGFGGDDCSKSV--C-PVLC---SQRGEYINGECQCNPGWK 931
            C    +CL G     C C  G+ G  C   +  C P  C   S +       C C PG+ 
Sbjct: 537  CKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYT 596

Query: 932  GKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEI---DCPHPTCSGHGF 984
            G  C    +EC    C   G C +      C C++G  G  C EI   DC    C   G 
Sbjct: 597  GHHCETNINECSSQPCRLRGTCQDPDNAYLCFCLKGTTGPNC-EINLDDCASSPCDS-GT 654

Query: 985  C---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGED 1038
            C   I+G  C C+ G+ G+ C + + D     P C   GT +  ++  TC C   +    
Sbjct: 655  CLDKIDGYECACEPGYTGSMCNS-NIDECAGNP-CHNGGTCEDGINGFTCRCPEGYHDPT 712

Query: 1039 CSKEVCSLECGP--HGRC----VGESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKNGT 1089
            C  EV      P  HG C     G  C C  GWSG  C +    C++  C   G CK+ T
Sbjct: 713  CLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMT 772

Query: 1090 ----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G +C   +  C  + C   G C +D+   ++C C   + G  C
Sbjct: 773  SGIVCTCREGFSGPNCQTNINECASNPCLNKGTC-IDDVAGYKCNCLLPYTGATC 826



 Score = 99.5 bits (237), Expect = 2e-19
 Identities = 91/313 (29%), Positives = 129/313 (41%), Gaps = 49/313 (15%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGEYING----ECQCNPGW 930
            C NG + K       C C+ GF G +C  ++       C  +G  I+     +C C   +
Sbjct: 762  CVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPY 821

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNGK------CSC-VRGYKGKFCGEID---CPHPTCS 980
             G  C +    C    C   G C   +      C C   G KG+ C E+D   C    C 
Sbjct: 822  TGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTC-EVDINECVLSPCR 880

Query: 981  GHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPD-CSGHG--TFDVDTQTCSCHA 1032
             HG   + T     C C+ G+ G +C T   D   C P+ C   G  T  ++T  C C  
Sbjct: 881  -HGASCQNTHGXYRCHCQAGYSGRNCET---DIDDCRPNPCHNGGSCTDGINTAFCDCLP 936

Query: 1033 KWSGEDCSKEV--CSLECGPHGR----CVGE-SCSCAAGWSGEFCSVRLCD---ARCAEH 1082
             + G  C +++  C+ +   +G     CV   +C+C AG+SG  C     D   + C   
Sbjct: 937  GFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG 996

Query: 1083 GQCKNG----TCLCVSGWNGRHC--TLEGCP-RSCAGHGQCRVDNDGRWECKCFDGWDGP 1135
            G C +G    TCLC  G+ G +C   +  C  R C   G C+ D  G   C C  G+ GP
Sbjct: 997  GTCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQ-DGRGLHRCTCPQGYTGP 1055

Query: 1136 DCTTLKEQICDDS 1148
            +C  L    CD S
Sbjct: 1056 NCQNLVHW-CDSS 1067



 Score = 98.7 bits (235), Expect = 3e-19
 Identities = 93/342 (27%), Positives = 136/342 (39%), Gaps = 48/342 (14%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV---------LCSQRGEYINGECQCNP 928
            C +G +   E     C C+    G +C +   P           C   G+ +  EC C P
Sbjct: 189  CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGD-VTHECACLP 247

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP--HPTCS 980
            G+ G+ C    D+C   +C   G CV+G     C C   + G++C E +D C      C 
Sbjct: 248  GFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEWTGQYCTEDVDECQLMPNACQ 307

Query: 981  GHGFC--IEG--TCVCKKGWKGADCGTMDKD--ALQCLPDCSGHGTFDVDTQTCSCHAKW 1034
              G C    G   CVC  GW G DC     D  +  C    + H    V +  C C    
Sbjct: 308  NGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDR--VASFYCECPHGR 365

Query: 1035 SGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFCS--VRLCD--ARCAEH 1082
            +G  C   + C S  C     C      G++ C+C +G++G  CS  V  C   A   EH
Sbjct: 366  TGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEH 425

Query: 1083 -GQCKN--GT--CLCVSGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
             G+C N  G+  C C+ G+ G  C +   E     C     C +D  G ++C C  G++G
Sbjct: 426  AGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATC-LDQIGEFQCMCMPGYEG 484

Query: 1135 PDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
              C    ++ C  S        +D  +   C+ P   +  LC
Sbjct: 485  VHCEVNTDE-CASSPCLHNGRCLDKINEFQCECPTGFTGHLC 525



 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 83/300 (27%), Positives = 117/300 (39%), Gaps = 45/300 (15%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSV--C---PVLCSQRGEYING-ECQCNPG 929
            N C   G C  G     C+C  G+    C   V  C   P +     + +NG +C C+PG
Sbjct: 685  NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 744

Query: 930  WKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPTCSGHG 983
            W G  C + ++ECE   C   G C    +G  C+C  G+ G  C     +C    C   G
Sbjct: 745  WSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLNKG 804

Query: 984  FCIEGT----CVCKKGWKGADCGTMDKDALQCLPD-CSGHG----TFDVDTQTCSC-HAK 1033
             CI+      C C   + GA C  +      C P  C   G    + D ++ +C C  A 
Sbjct: 805  TCIDDVAGYKCNCLLPYTGATCEVV---LAPCAPSPCRNGGECRQSEDYESFSCVCPTAG 861

Query: 1034 WSGEDCSKEV--CSLECGPHGRCVGES-----CSCAAGWSGEFCSVRLCDAR---CAEHG 1083
              G+ C  ++  C L    HG     +     C C AG+SG  C   + D R   C   G
Sbjct: 862  AKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGG 921

Query: 1084 QCKNGT----CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +G     C C+ G+ G  C   +  C      +G    D    + C C  G+ G  C
Sbjct: 922  SCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHC 981



 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 77/285 (27%), Positives = 109/285 (38%), Gaps = 41/285 (14%)

Query: 902  DDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK---- 957
            ++C  S C    S +  +    C C  G+ G+ C    D+C    C+  G C +G     
Sbjct: 872  NECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF 931

Query: 958  CSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQC 1011
            C C+ G++G FC E   +C    C     C +     TC C  G+ G  C     D  + 
Sbjct: 932  CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTES 991

Query: 1012 LPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCA 1062
               C   GT    +++ TC C   ++G  C   V  C S  C   G C        C+C 
Sbjct: 992  --SCFNGGTCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCP 1049

Query: 1063 AGWSGEFCS--VRLCDAR-CAEHGQC----KNGTCLCVSGWNGRHCTLEGCPRSCAG--- 1112
             G++G  C   V  CD+  C   G+C        C C SGW G +C +       A    
Sbjct: 1050 QGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQ 1109

Query: 1113 ---------HGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
                     HG   VD      C+C  G+ G  C  L ++ C  S
Sbjct: 1110 GVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDE-CSPS 1153



 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 82/308 (26%), Positives = 117/308 (37%), Gaps = 51/308 (16%)

Query: 879  PNGCSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRGEYING-----ECQCN 927
            PN C   G C  G     C C PGF G  C + +  C     + G           C C 
Sbjct: 914  PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP 973

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEI--DCPHPTCSG 981
             G+ G  C     +C    C   G CV+G     C C  G+ G +C  +  +C    C  
Sbjct: 974  AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLL 1033

Query: 982  HGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSG 1036
             G C +G     C C +G+ G +C  +        P  +G   +   TQ  C C + W+G
Sbjct: 1034 GGTCQDGRGLHRCTCPQGYTGPNCQNL-VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTG 1092

Query: 1037 EDCSKEVCSLE-------------CGPHGRCVG----ESCSCAAGWSGEFCS--VRLCD- 1076
              C     S E             C   G CV       C C AG++G +C   V  C  
Sbjct: 1093 LYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSP 1152

Query: 1077 ARCAEHGQCKN----GTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCF 1129
            + C     C +     +C CV+G++G +C+  ++ C    C   G C +D    ++C C 
Sbjct: 1153 SPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC-LDLPNTYKCSCP 1211

Query: 1130 DGWDGPDC 1137
             G  G  C
Sbjct: 1212 RGTQGVHC 1219



 Score = 94.7 bits (225), Expect = 5e-18
 Identities = 94/358 (26%), Positives = 141/358 (39%), Gaps = 47/358 (13%)

Query: 874  MTHNCPNGCSGKGECLMGH-CQCQPGFGGDDCSKS--VCPVLCSQRGEYINGE----CQC 926
            +T+ C NG +     L  + C+C PG+ G  C ++       C+  G+ +  E    C C
Sbjct: 107  LTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHC 166

Query: 927  NPGWKGKECSLRHDEC-EVPD-CNGHGHCVNG----KCSCVRGYKGKFCGE--IDCPHPT 978
             P + G  C    +EC + P  C   G C N     +C C   + G  C    + C    
Sbjct: 167  PPSFHGPTCRQDVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSP 226

Query: 979  CSGHGFC-----IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAK 1033
            C   G C     +   C C  G+ G +C     D         G     V+T  C C  +
Sbjct: 227  CQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPE 286

Query: 1034 WSGEDCSKEV--CSL---ECGPHGRC----VGESCSCAAGWSGEFCSVRLCD---ARCAE 1081
            W+G+ C+++V  C L    C   G C     G +C C  GW+GE CS  + D   A C  
Sbjct: 287  WTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFH 346

Query: 1082 HGQCKNGT----CLCVSGWNGRHCTL-EGC-PRSCAGHGQCRVDN-DGRWECKCFDGWDG 1134
               C +      C C  G  G  C L + C    C     C  +  +G+  C C  G+ G
Sbjct: 347  GATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTG 406

Query: 1135 PDCT------TLKEQICDDS-RDNDKDGLVDCEDPECCQSPACK-SSQLCVSSPKPTD 1184
            P C+      +L    C+ + +  +  G  +C+  +    P C+     CVS+P   D
Sbjct: 407  PACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQND 464



 Score = 93.9 bits (223), Expect = 8e-18
 Identities = 94/317 (29%), Positives = 123/317 (38%), Gaps = 63/317 (19%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSV--CPVL-CSQRGEYING----ECQCNPG 929
            C NG +   +C+  + C C  GF G  C  +   C    C   G  ++G     C C PG
Sbjct: 955  CRNGANCT-DCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG 1013

Query: 930  WKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID--CPHPTCSGHG 983
            + G  C    +EC+   C   G C +G    +C+C +GY G  C  +   C    C   G
Sbjct: 1014 FTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 1073

Query: 984  FC----IEGTCVCKKGWKGADCG--------TMDKDALQCLPDCSGHGTFDVD---TQTC 1028
             C     +  C C  GW G  C            +  +     C  HG   VD   T  C
Sbjct: 1074 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQ-HGGLCVDAGNTHHC 1132

Query: 1029 SCHAKWSGEDCSKEV--CS-LECGPHGRCV----GESCSCAAGWSGEFCSVRLCDARCAE 1081
             C A ++G  C   V  CS   C     C     G SC C AG+ G  CS  + +  C  
Sbjct: 1133 RCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDE--CLS 1190

Query: 1082 HGQCKN-GTCL---------CVSGWNGRHC--TLEGC-----PRS----CAGHGQCRVDN 1120
            H  C+N GTCL         C  G  G HC   ++ C     P S    C  +G C VD 
Sbjct: 1191 H-PCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC-VDQ 1248

Query: 1121 DGRWECKCFDGWDGPDC 1137
             G + C C  G+ G  C
Sbjct: 1249 VGGYSCTCPPGFVGERC 1265



 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 103/387 (26%), Positives = 150/387 (38%), Gaps = 89/387 (22%)

Query: 866  FVALVAEEMTHNCPNG-CSGKGECLMGH----CQCQPGFGGDDCSKSV--CPVL-CSQRG 917
            F     + + + C +  C   G C  G     C C  G+ G +C   V  C    C   G
Sbjct: 1014 FTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 1073

Query: 918  E----YINGECQCNPGWKGKECSLRHDECEVPD----------CNGHGHCVNG----KCS 959
            +    +    C+C  GW G  C +    CEV            C   G CV+      C 
Sbjct: 1074 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCR 1133

Query: 960  CVRGYKGKFCGEI--DCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLP 1013
            C  GY G +C ++  +C    C     C +     +C C  G+ G +C    ++  +CL 
Sbjct: 1134 CQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCS---EEIDECLS 1190

Query: 1014 D-CSGHGT-FDV-DTQTCSC-------HAKWSGEDCSKEVC----SLECGPHGRCV---- 1055
              C   GT  D+ +T  CSC       H + + +DC+  V     S +C  +G CV    
Sbjct: 1191 HPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVG 1250

Query: 1056 GESCSCAAGWSGEFCSVRL-------CDARCAEH--GQCKNGTCLCVSGWNGRHC--TLE 1104
            G SC+C  G+ GE C   +       CDAR  ++   +  +  C C +G  GR C   + 
Sbjct: 1251 GYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVIN 1310

Query: 1105 GCP-RSCAGHGQCRV-DNDGR-WECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
            GC  + C   G C V  N  R + CKC  G++G  C                       D
Sbjct: 1311 GCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN---------------------D 1349

Query: 1162 PECCQSPACKSSQLCVSSPK-PTDILL 1187
               C S  C +   C+S P+ PT + L
Sbjct: 1350 ARTCGSLRCLNGGTCISGPRSPTCLCL 1376



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 81/317 (25%), Positives = 111/317 (35%), Gaps = 59/317 (18%)

Query: 866  FVALVAEEMTHNC-PNGCSGKG--ECLMG----HCQCQPGFGGDDCSKSV--C---PV-- 911
            FV    E   + C  N C  +G   C+      HC+C+ G  G  C   +  C   P   
Sbjct: 1260 FVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN 1319

Query: 912  --LCSQRGEYINGE-CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGY 964
               C+       G  C+C  G++G  C      C    C   G C++G     C C+  +
Sbjct: 1320 GGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPF 1379

Query: 965  KGKFCGEIDCPHPTCSGHGFCIEGTC--VCKKGWKGADCGTMDKDALQCLPDCS--GHGT 1020
             G  C +     P   G+    +GTC    +  +    C       L  + D S  G   
Sbjct: 1380 TGPEC-QFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAG 1438

Query: 1021 FDVDTQTC--SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCD-- 1076
             D+       +C      ED   +VCSL+C  H          A GW G  CS+   D  
Sbjct: 1439 RDIPPPLIEEACELPECQEDAGNKVCSLQCNNH----------ACGWDGGDCSLNFNDPW 1488

Query: 1077 ARCAEHGQCKN--GTCLCVSGWNGRHCTLEG--CPRSCAGHGQCR--VD-------NDGR 1123
              C +  QC        C S  N   C  +G  C R+    GQC    D       +DG 
Sbjct: 1489 KNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRA---EGQCNPLYDQYCKDHFSDGH 1545

Query: 1124 WECKCFDG---WDGPDC 1137
             +  C      WDG DC
Sbjct: 1546 CDQGCNSAECEWDGLDC 1562



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 33/118 (27%), Positives = 50/118 (42%), Gaps = 16/118 (13%)

Query: 1079 CAEHGQCK--NGT--CLCVSGWNGRHCTLEG-CPRS-CAGHGQCRV-DNDG--RWECKCF 1129
            C   G+C+  NGT  C+C   + G  C     C  + C   G C V D  G   + C C 
Sbjct: 31   CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90

Query: 1130 DGWDGPDCTTLKEQIC--DDSRDNDKDGLVDCEDPECCQSP-----ACKSSQLCVSSP 1180
             G+ GP C T  +  C  +  R+     L+   + +C   P     +C+ +  C S+P
Sbjct: 91   LGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNP 148



 Score = 34.3 bits (75), Expect = 6.8
 Identities = 25/95 (26%), Positives = 34/95 (35%), Gaps = 14/95 (14%)

Query: 1057 ESCSCAAGWSGEFCS-VRLC-DARCAEHGQC----KNGT----CLCVSGWNGRHCTL--- 1103
            E+C C   + G  C     C    C   G C    + G     C C  G++G  C     
Sbjct: 44   EACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLD 103

Query: 1104 EGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C    C   G C +     ++C+C  GW G  C
Sbjct: 104  NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSC 138


>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
          Length = 2556

 Score =  111 bits (267), Expect = 4e-23
 Identities = 93/345 (26%), Positives = 139/345 (40%), Gaps = 48/345 (13%)

Query: 880  NGCSGKGECL--MGH--CQCQPGFGG-------DDCSKSVCPVLCSQRGEYINGECQCNP 928
            N C     CL  +G   C C PG+ G       D+C+ S C        +    +C+C  
Sbjct: 459  NPCQNDATCLDQIGEFQCMCMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPT 518

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EIDCPHPTCSGHG 983
            G+ G  C    DEC    C     C++G     C C  GY G  C  +ID   P    +G
Sbjct: 519  GFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG 578

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF-DVD-TQTCSCHAKWSGE 1037
             C +G    TC+C+ G+ G  C T   +       C   GT  D D    C C    +G 
Sbjct: 579  SCKDGVATFTCLCRPGYTGHHCETNINECSS--QPCRLRGTCQDPDNAYLCFCLKGTTGP 636

Query: 1038 DC--SKEVCSLECGPHGRCV----GESCSCAAGWSGEFCSVRLCDAR---CAEHGQCKNG 1088
            +C  + + C+      G C+    G  C+C  G++G  C+  + +     C   G C++G
Sbjct: 637  NCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNSNIDECAGNPCHNGGTCEDG 696

Query: 1089 ----TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
                TC C  G++   C  E   C  +   HG CR D+   ++C C  GW G +C  +  
Sbjct: 697  INGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACR-DSLNGYKCDCDPGWSGTNC-DINN 754

Query: 1143 QICDDS------RDNDKDGLVDCEDPECCQSPACKSS-QLCVSSP 1180
              C+ +         D    + C   E    P C+++   C S+P
Sbjct: 755  NECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNP 799



 Score =  106 bits (255), Expect = 1e-21
 Identities = 88/306 (28%), Positives = 126/306 (41%), Gaps = 41/306 (13%)

Query: 888  CLMGHCQCQPGFGGDDCSKSVCPV-LCSQRGEYING-ECQCNPGWKGKECSLRHDECEVP 945
            CL G          DDC+ S C    C  +   I+G EC C PG+ G  C+   DEC   
Sbjct: 629  CLKGTTGPNCEINLDDCASSPCDSGTCLDK---IDGYECACEPGYTGSMCNSNIDECAGN 685

Query: 946  DCNGHGHC---VNG-KCSCVRGYKGKFC-GEI-DCPHPTCSGHGFCIEG----TCVCKKG 995
             C+  G C   +NG  C C  GY    C  E+ +C    C  HG C +      C C  G
Sbjct: 686  PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV-HGACRDSLNGYKCDCDPG 744

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCS---KEVCSLECGPH 1051
            W G +C  ++ +  +  P  +G    D+ +   C+C   +SG +C     E  S  C   
Sbjct: 745  WSGTNC-DINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLNK 803

Query: 1052 GRCV----GESCSCAAGWSGEFCSVRL---CDARCAEHGQCKNG------TCLC-VSGWN 1097
            G C+    G  C+C   ++G  C V L     + C   G+C+        +C+C  +G  
Sbjct: 804  GTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGAK 863

Query: 1098 GRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG 1155
            G+ C ++   C  S   HG    +  G + C C  G+ G +C    E   DD R N    
Sbjct: 864  GQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNC----ETDIDDCRPNPCHN 919

Query: 1156 LVDCED 1161
               C D
Sbjct: 920  GGSCTD 925



 Score =  103 bits (248), Expect = 7e-21
 Identities = 99/340 (29%), Positives = 135/340 (39%), Gaps = 60/340 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKECSLRHDECEV 944
            HC+CQ G+ G  C   V  C     Q G    +Y+ G  C+C  G+ G  CS   DEC  
Sbjct: 1131 HCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLS 1190

Query: 945  PDCNGHGHCVN----GKCSCVRGYKGKFCGEI---DC--------PHPTCSGHGFCIEG- 988
              C   G C++     KCSC RG +G  C EI   DC          P C  +G C++  
Sbjct: 1191 HPCQNGGTCLDLPNTYKCSCPRGTQGVHC-EINVDDCNPPVDPVSRSPKCFNNGTCVDQV 1249

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFD----VDTQTCSCHAKWSGEDCS 1040
               +C C  G+ G  C   + D  +CL + C   GT +    V+   C C A  +G  C 
Sbjct: 1250 GGYSCTCPPGFVGERC---EGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE 1306

Query: 1041 KEV--C-SLECGPHGRCV-------GESCSCAAGWSGEFC--SVRLCDA-RCAEHGQCKN 1087
              +  C    C   G C        G  C C AG+ G  C    R C + RC   G C +
Sbjct: 1307 SVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCIS 1366

Query: 1088 G----TCLCVSGWNGRHCTLEG---C--PRSCAGHGQCRVDNDGR-WECKCFDGWDGPDC 1137
            G    TCLC+  + G  C       C     C   G C   ++   + C C   ++G  C
Sbjct: 1367 GPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1426

Query: 1138 TTLKEQICDDSRDNDKDGLVD--CEDPECCQSPACKSSQL 1175
              L       +  +    L++  CE PEC +    K   L
Sbjct: 1427 HILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSL 1466



 Score =  102 bits (244), Expect = 2e-20
 Identities = 86/295 (29%), Positives = 119/295 (40%), Gaps = 44/295 (14%)

Query: 882  CSGKGECLMGH----CQCQPGFGGDDCSKSV--C-PVLC---SQRGEYINGECQCNPGWK 931
            C    +CL G     C C  G+ G  C   +  C P  C   S +       C C PG+ 
Sbjct: 537  CKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYT 596

Query: 932  GKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEI---DCPHPTCSGHGF 984
            G  C    +EC    C   G C +      C C++G  G  C EI   DC    C   G 
Sbjct: 597  GHHCETNINECSSQPCRLRGTCQDPDNAYLCFCLKGTTGPNC-EINLDDCASSPCDS-GT 654

Query: 985  C---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTCSCHAKWSGED 1038
            C   I+G  C C+ G+ G+ C + + D     P C   GT +  ++  TC C   +    
Sbjct: 655  CLDKIDGYECACEPGYTGSMCNS-NIDECAGNP-CHNGGTCEDGINGFTCRCPEGYHDPT 712

Query: 1039 CSKEVCSLECGP--HGRC----VGESCSCAAGWSGEFCSV--RLCDAR-CAEHGQCKNGT 1089
            C  EV      P  HG C     G  C C  GWSG  C +    C++  C   G CK+ T
Sbjct: 713  CLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMT 772

Query: 1090 ----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                C C  G++G +C   +  C  + C   G C +D+   ++C C   + G  C
Sbjct: 773  SGIVCTCREGFSGPNCQTNINECASNPCLNKGTC-IDDVAGYKCNCLLPYTGATC 826



 Score = 99.5 bits (237), Expect = 2e-19
 Identities = 91/313 (29%), Positives = 129/313 (41%), Gaps = 49/313 (15%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGEYING----ECQCNPGW 930
            C NG + K       C C+ GF G +C  ++       C  +G  I+     +C C   +
Sbjct: 762  CVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLNKGTCIDDVAGYKCNCLLPY 821

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNGK------CSC-VRGYKGKFCGEID---CPHPTCS 980
             G  C +    C    C   G C   +      C C   G KG+ C E+D   C    C 
Sbjct: 822  TGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTAGAKGQTC-EVDINECVLSPCR 880

Query: 981  GHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPD-CSGHG--TFDVDTQTCSCHA 1032
             HG   + T     C C+ G+ G +C T   D   C P+ C   G  T  ++T  C C  
Sbjct: 881  -HGASCQNTHGXYRCHCQAGYSGRNCET---DIDDCRPNPCHNGGSCTDGINTAFCDCLP 936

Query: 1033 KWSGEDCSKEV--CSLECGPHGR----CVGE-SCSCAAGWSGEFCSVRLCD---ARCAEH 1082
             + G  C +++  C+ +   +G     CV   +C+C AG+SG  C     D   + C   
Sbjct: 937  GFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNG 996

Query: 1083 GQCKNG----TCLCVSGWNGRHC--TLEGCP-RSCAGHGQCRVDNDGRWECKCFDGWDGP 1135
            G C +G    TCLC  G+ G +C   +  C  R C   G C+ D  G   C C  G+ GP
Sbjct: 997  GTCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQ-DGRGLHRCTCPQGYTGP 1055

Query: 1136 DCTTLKEQICDDS 1148
            +C  L    CD S
Sbjct: 1056 NCQNLVHW-CDSS 1067



 Score = 98.7 bits (235), Expect = 3e-19
 Identities = 93/342 (27%), Positives = 136/342 (39%), Gaps = 48/342 (14%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV---------LCSQRGEYINGECQCNP 928
            C +G +   E     C C+    G +C +   P           C   G+ +  EC C P
Sbjct: 189  CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGD-VTHECACLP 247

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CP--HPTCS 980
            G+ G+ C    D+C   +C   G CV+G     C C   + G++C E +D C      C 
Sbjct: 248  GFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPEWTGQYCTEDVDECQLMPNACQ 307

Query: 981  GHGFC--IEG--TCVCKKGWKGADCGTMDKD--ALQCLPDCSGHGTFDVDTQTCSCHAKW 1034
              G C    G   CVC  GW G DC     D  +  C    + H    V +  C C    
Sbjct: 308  NGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDR--VASFYCECPHGR 365

Query: 1035 SGEDCS-KEVC-SLECGPHGRC-----VGES-CSCAAGWSGEFCS--VRLCD--ARCAEH 1082
            +G  C   + C S  C     C      G++ C+C +G++G  CS  V  C   A   EH
Sbjct: 366  TGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEH 425

Query: 1083 -GQCKN--GT--CLCVSGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
             G+C N  G+  C C+ G+ G  C +   E     C     C +D  G ++C C  G++G
Sbjct: 426  AGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATC-LDQIGEFQCMCMPGYEG 484

Query: 1135 PDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLC 1176
              C    ++ C  S        +D  +   C+ P   +  LC
Sbjct: 485  VHCEVNTDE-CASSPCLHNGRCLDKINEFQCECPTGFTGHLC 525



 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 83/300 (27%), Positives = 117/300 (39%), Gaps = 45/300 (15%)

Query: 880  NGCSGKGECLMG----HCQCQPGFGGDDCSKSV--C---PVLCSQRGEYING-ECQCNPG 929
            N C   G C  G     C+C  G+    C   V  C   P +     + +NG +C C+PG
Sbjct: 685  NPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPG 744

Query: 930  WKGKECSLRHDECEVPDCNGHGHC---VNG-KCSCVRGYKGKFC--GEIDCPHPTCSGHG 983
            W G  C + ++ECE   C   G C    +G  C+C  G+ G  C     +C    C   G
Sbjct: 745  WSGTNCDINNNECESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNINECASNPCLNKG 804

Query: 984  FCIEGT----CVCKKGWKGADCGTMDKDALQCLPD-CSGHG----TFDVDTQTCSC-HAK 1033
             CI+      C C   + GA C  +      C P  C   G    + D ++ +C C  A 
Sbjct: 805  TCIDDVAGYKCNCLLPYTGATCEVV---LAPCAPSPCRNGGECRQSEDYESFSCVCPTAG 861

Query: 1034 WSGEDCSKEV--CSLECGPHGRCVGES-----CSCAAGWSGEFCSVRLCDAR---CAEHG 1083
              G+ C  ++  C L    HG     +     C C AG+SG  C   + D R   C   G
Sbjct: 862  AKGQTCEVDINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGG 921

Query: 1084 QCKNGT----CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C +G     C C+ G+ G  C   +  C      +G    D    + C C  G+ G  C
Sbjct: 922  SCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHC 981



 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 77/285 (27%), Positives = 109/285 (38%), Gaps = 41/285 (14%)

Query: 902  DDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK---- 957
            ++C  S C    S +  +    C C  G+ G+ C    D+C    C+  G C +G     
Sbjct: 872  NECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF 931

Query: 958  CSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQC 1011
            C C+ G++G FC E   +C    C     C +     TC C  G+ G  C     D  + 
Sbjct: 932  CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTES 991

Query: 1012 LPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVG----ESCSCA 1062
               C   GT    +++ TC C   ++G  C   V  C S  C   G C        C+C 
Sbjct: 992  --SCFNGGTCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCP 1049

Query: 1063 AGWSGEFCS--VRLCDAR-CAEHGQC----KNGTCLCVSGWNGRHCTLEGCPRSCAG--- 1112
             G++G  C   V  CD+  C   G+C        C C SGW G +C +       A    
Sbjct: 1050 QGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQ 1109

Query: 1113 ---------HGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
                     HG   VD      C+C  G+ G  C  L ++ C  S
Sbjct: 1110 GVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDE-CSPS 1153



 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 82/308 (26%), Positives = 117/308 (37%), Gaps = 51/308 (16%)

Query: 879  PNGCSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRGEYING-----ECQCN 927
            PN C   G C  G     C C PGF G  C + +  C     + G           C C 
Sbjct: 914  PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCP 973

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEI--DCPHPTCSG 981
             G+ G  C     +C    C   G CV+G     C C  G+ G +C  +  +C    C  
Sbjct: 974  AGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHVVNECDSRPCLL 1033

Query: 982  HGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSG 1036
             G C +G     C C +G+ G +C  +        P  +G   +   TQ  C C + W+G
Sbjct: 1034 GGTCQDGRGLHRCTCPQGYTGPNCQNL-VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTG 1092

Query: 1037 EDCSKEVCSLE-------------CGPHGRCVG----ESCSCAAGWSGEFCS--VRLCD- 1076
              C     S E             C   G CV       C C AG++G +C   V  C  
Sbjct: 1093 LYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSP 1152

Query: 1077 ARCAEHGQCKN----GTCLCVSGWNGRHCT--LEGC-PRSCAGHGQCRVDNDGRWECKCF 1129
            + C     C +     +C CV+G++G +C+  ++ C    C   G C +D    ++C C 
Sbjct: 1153 SPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC-LDLPNTYKCSCP 1211

Query: 1130 DGWDGPDC 1137
             G  G  C
Sbjct: 1212 RGTQGVHC 1219



 Score = 94.7 bits (225), Expect = 5e-18
 Identities = 94/358 (26%), Positives = 141/358 (39%), Gaps = 47/358 (13%)

Query: 874  MTHNCPNGCSGKGECLMGH-CQCQPGFGGDDCSKS--VCPVLCSQRGEYINGE----CQC 926
            +T+ C NG +     L  + C+C PG+ G  C ++       C+  G+ +  E    C C
Sbjct: 107  LTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHC 166

Query: 927  NPGWKGKECSLRHDEC-EVPD-CNGHGHCVNG----KCSCVRGYKGKFCGE--IDCPHPT 978
             P + G  C    +EC + P  C   G C N     +C C   + G  C    + C    
Sbjct: 167  PPSFHGPTCRQDVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSP 226

Query: 979  CSGHGFC-----IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAK 1033
            C   G C     +   C C  G+ G +C     D         G     V+T  C C  +
Sbjct: 227  CQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCPCPPE 286

Query: 1034 WSGEDCSKEV--CSL---ECGPHGRC----VGESCSCAAGWSGEFCSVRLCD---ARCAE 1081
            W+G+ C+++V  C L    C   G C     G +C C  GW+GE CS  + D   A C  
Sbjct: 287  WTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFH 346

Query: 1082 HGQCKNGT----CLCVSGWNGRHCTL-EGC-PRSCAGHGQCRVDN-DGRWECKCFDGWDG 1134
               C +      C C  G  G  C L + C    C     C  +  +G+  C C  G+ G
Sbjct: 347  GATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTG 406

Query: 1135 PDCT------TLKEQICDDS-RDNDKDGLVDCEDPECCQSPACK-SSQLCVSSPKPTD 1184
            P C+      +L    C+ + +  +  G  +C+  +    P C+     CVS+P   D
Sbjct: 407  PACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQND 464



 Score = 93.9 bits (223), Expect = 8e-18
 Identities = 94/317 (29%), Positives = 123/317 (38%), Gaps = 63/317 (19%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSV--CPVL-CSQRGEYING----ECQCNPG 929
            C NG +   +C+  + C C  GF G  C  +   C    C   G  ++G     C C PG
Sbjct: 955  CRNGANCT-DCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG 1013

Query: 930  WKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID--CPHPTCSGHG 983
            + G  C    +EC+   C   G C +G    +C+C +GY G  C  +   C    C   G
Sbjct: 1014 FTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 1073

Query: 984  FC----IEGTCVCKKGWKGADCG--------TMDKDALQCLPDCSGHGTFDVD---TQTC 1028
             C     +  C C  GW G  C            +  +     C  HG   VD   T  C
Sbjct: 1074 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQ-HGGLCVDAGNTHHC 1132

Query: 1029 SCHAKWSGEDCSKEV--CS-LECGPHGRCV----GESCSCAAGWSGEFCSVRLCDARCAE 1081
             C A ++G  C   V  CS   C     C     G SC C AG+ G  CS  + +  C  
Sbjct: 1133 RCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDE--CLS 1190

Query: 1082 HGQCKN-GTCL---------CVSGWNGRHC--TLEGC-----PRS----CAGHGQCRVDN 1120
            H  C+N GTCL         C  G  G HC   ++ C     P S    C  +G C VD 
Sbjct: 1191 H-PCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTC-VDQ 1248

Query: 1121 DGRWECKCFDGWDGPDC 1137
             G + C C  G+ G  C
Sbjct: 1249 VGGYSCTCPPGFVGERC 1265



 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 103/387 (26%), Positives = 150/387 (38%), Gaps = 89/387 (22%)

Query: 866  FVALVAEEMTHNCPNG-CSGKGECLMGH----CQCQPGFGGDDCSKSV--CPVL-CSQRG 917
            F     + + + C +  C   G C  G     C C  G+ G +C   V  C    C   G
Sbjct: 1014 FTGSYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 1073

Query: 918  E----YINGECQCNPGWKGKECSLRHDECEVPD----------CNGHGHCVNG----KCS 959
            +    +    C+C  GW G  C +    CEV            C   G CV+      C 
Sbjct: 1074 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCR 1133

Query: 960  CVRGYKGKFCGEI--DCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLP 1013
            C  GY G +C ++  +C    C     C +     +C C  G+ G +C    ++  +CL 
Sbjct: 1134 CQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCS---EEIDECLS 1190

Query: 1014 D-CSGHGT-FDV-DTQTCSC-------HAKWSGEDCSKEVC----SLECGPHGRCV---- 1055
              C   GT  D+ +T  CSC       H + + +DC+  V     S +C  +G CV    
Sbjct: 1191 HPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVG 1250

Query: 1056 GESCSCAAGWSGEFCSVRL-------CDARCAEH--GQCKNGTCLCVSGWNGRHC--TLE 1104
            G SC+C  G+ GE C   +       CDAR  ++   +  +  C C +G  GR C   + 
Sbjct: 1251 GYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVIN 1310

Query: 1105 GCP-RSCAGHGQCRV-DNDGR-WECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
            GC  + C   G C V  N  R + CKC  G++G  C                       D
Sbjct: 1311 GCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN---------------------D 1349

Query: 1162 PECCQSPACKSSQLCVSSPK-PTDILL 1187
               C S  C +   C+S P+ PT + L
Sbjct: 1350 ARTCGSLRCLNGGTCISGPRSPTCLCL 1376



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 81/317 (25%), Positives = 111/317 (35%), Gaps = 59/317 (18%)

Query: 866  FVALVAEEMTHNC-PNGCSGKG--ECLMG----HCQCQPGFGGDDCSKSV--C---PV-- 911
            FV    E   + C  N C  +G   C+      HC+C+ G  G  C   +  C   P   
Sbjct: 1260 FVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN 1319

Query: 912  --LCSQRGEYINGE-CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGY 964
               C+       G  C+C  G++G  C      C    C   G C++G     C C+  +
Sbjct: 1320 GGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPF 1379

Query: 965  KGKFCGEIDCPHPTCSGHGFCIEGTC--VCKKGWKGADCGTMDKDALQCLPDCS--GHGT 1020
             G  C +     P   G+    +GTC    +  +    C       L  + D S  G   
Sbjct: 1380 TGPEC-QFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAG 1438

Query: 1021 FDVDTQTC--SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCD-- 1076
             D+       +C      ED   +VCSL+C  H          A GW G  CS+   D  
Sbjct: 1439 RDIPPPLIEEACELPECQEDAGNKVCSLQCNNH----------ACGWDGGDCSLNFNDPW 1488

Query: 1077 ARCAEHGQCKN--GTCLCVSGWNGRHCTLEG--CPRSCAGHGQCR--VD-------NDGR 1123
              C +  QC        C S  N   C  +G  C R+    GQC    D       +DG 
Sbjct: 1489 KNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRA---EGQCNPLYDQYCKDHFSDGH 1545

Query: 1124 WECKCFDG---WDGPDC 1137
             +  C      WDG DC
Sbjct: 1546 CDQGCNSAECEWDGLDC 1562



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 33/118 (27%), Positives = 50/118 (42%), Gaps = 16/118 (13%)

Query: 1079 CAEHGQCK--NGT--CLCVSGWNGRHCTLEG-CPRS-CAGHGQCRV-DNDG--RWECKCF 1129
            C   G+C+  NGT  C+C   + G  C     C  + C   G C V D  G   + C C 
Sbjct: 31   CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90

Query: 1130 DGWDGPDCTTLKEQIC--DDSRDNDKDGLVDCEDPECCQSP-----ACKSSQLCVSSP 1180
             G+ GP C T  +  C  +  R+     L+   + +C   P     +C+ +  C S+P
Sbjct: 91   LGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNP 148



 Score = 34.3 bits (75), Expect = 6.8
 Identities = 25/95 (26%), Positives = 34/95 (35%), Gaps = 14/95 (14%)

Query: 1057 ESCSCAAGWSGEFCS-VRLC-DARCAEHGQC----KNGT----CLCVSGWNGRHCTL--- 1103
            E+C C   + G  C     C    C   G C    + G     C C  G++G  C     
Sbjct: 44   EACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLD 103

Query: 1104 EGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C    C   G C +     ++C+C  GW G  C
Sbjct: 104  NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSC 138


>AB023961-1|BAB20317.1|  502|Homo sapiens notch4 protein.
          Length = 502

 Score =  110 bits (265), Expect = 6e-23
 Identities = 95/309 (30%), Positives = 126/309 (40%), Gaps = 53/309 (17%)

Query: 879  PNGCSGKGECLMG-----HCQCQPGFGGDDCS-KSVCPVL-CSQRG----EYINGECQCN 927
            P+ CS +G C +       C C PG+ G+ C  +  C    C   G     Y   +C C 
Sbjct: 123  PSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCP 182

Query: 928  PGWKGKECSLRHDEC--EVPDCNGHGHCVNG----KCSCVRGYKGKFCGEI---DCPHPT 978
            PG++G  C    +EC  +   C     C N     +C C  G +G  C E+    CP   
Sbjct: 183  PGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRC-ELRAGPCPPRG 241

Query: 979  CSGHGFCI-----EGT---CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD--VDTQTC 1028
            CS  G C      + T   C+C  G+ G  C     + +     C   GT    +DT TC
Sbjct: 242  CSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVS--HQCQNGGTCQDGLDTYTC 299

Query: 1029 SCHAKWSGEDCSKEV--CSLECGPH----GRCVGES----CSCAAGWSGEFCSVRLCD-- 1076
             C   W+G DCS++V  C  +  PH    G C   +    C C +GW G  C   L D  
Sbjct: 300  LCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCI 359

Query: 1077 -ARCAEHGQC----KNGTCLCVSGWNGRHCTLEG-C-PRSCAGHGQCRVDN-DGRWECKC 1128
             A CA    C     + +CLC  G  G  C LE  C  + C G  QC  +   G   C C
Sbjct: 360  AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLC 419

Query: 1129 FDGWDGPDC 1137
              G+ GP C
Sbjct: 420  QPGYSGPTC 428



 Score =  105 bits (253), Expect = 2e-21
 Identities = 87/311 (27%), Positives = 120/311 (38%), Gaps = 54/311 (17%)

Query: 880  NGCSGKGECLMGH----CQCQPGFGGDDCSKSV---------CPVLCSQRGEYINGECQC 926
            N C   G CL  +    C C PGF G  C + V         CP   S      + +C C
Sbjct: 162  NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 221

Query: 927  NPGWKGKECSLRHDECEVPDCNGHGHC--------VNGKCSCVRGYKGKFC--GEIDCPH 976
              G +G  C LR   C    C+  G C            C C  G+ G  C     +C  
Sbjct: 222  PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVS 281

Query: 977  PTCSGHGFCIEG----TCVCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVDTQT--CS 1029
              C   G C +G    TC+C + W G DC   +D+   Q  P C   GT      +  C 
Sbjct: 282  HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCV 341

Query: 1030 CHAKWSGEDCSKEV--C-SLECGPHGRCVGE----SCSCAAGWSGEFCSVR-LC------ 1075
            C + W G  C + +  C +  C P   C+      SC C  G +G  C +  +C      
Sbjct: 342  CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCH 401

Query: 1076 -DARCAEHGQCKNGTCLCVSGWNGRHC--TLEGC------PRSCAGHGQCRVDNDGRWEC 1126
             DA+C+ +    +  CLC  G++G  C   L+ C      P  C   G C ++  G + C
Sbjct: 402  GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC-LNTPGSFNC 460

Query: 1127 KCFDGWDGPDC 1137
             C  G+ G  C
Sbjct: 461  LCPPGYTGSRC 471



 Score =  104 bits (250), Expect = 4e-21
 Identities = 91/292 (31%), Positives = 120/292 (41%), Gaps = 51/292 (17%)

Query: 893  CQCQPGFGGDDCSKSV---C-PVLCSQRGE-YING----ECQCNPGWKGKECSLRHDECE 943
            C C PGF G+ C   +   C P  CS+RG  +I      +C C PGW G++C LR D C 
Sbjct: 102  CTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCS 160

Query: 944  VPDCNGHGHCV----NGKCSCVRGYKGKFCGE--IDC---PHPTCSG---HGFCIEGTCV 991
               C   G C+      +C C  G++G  C     +C   P P   G   H       C+
Sbjct: 161  ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCL 220

Query: 992  CKKGWKGADCGTMDKDALQCLP-DCSGHGTF------DVDTQTCSCHAKWSGEDC--SKE 1042
            C  G +G  C   +  A  C P  CS  GT       D     C C   + G  C  + +
Sbjct: 221  CPVGQEGPRC---ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPD 277

Query: 1043 VC-SLECGPHGRCVG----ESCSCAAGWSGEFCS--VRLCDAR----CAEHGQCKNGT-- 1089
             C S +C   G C       +C C   W+G  CS  V  C+A+    C   G C+N    
Sbjct: 278  NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPPHCRNGGTCQNSAGS 337

Query: 1090 --CLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C+CVSGW G  C   L+ C  +    G   +D  G + C C  G  G  C
Sbjct: 338  FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 389



 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 84/308 (27%), Positives = 116/308 (37%), Gaps = 62/308 (20%)

Query: 922  GECQCNPGWKGKECSLRHDECEVPD-CNGHGHCV------------------NGKCSCVR 962
            G CQC PG+ G+ C    D C+    C   G C                   +  C+C+ 
Sbjct: 48   GTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 106

Query: 963  GYKGKFCG---EIDCPHPTCSGHGFC-IEGT----CVCKKGWKGADCGTMDKDALQCLPD 1014
            G+ G+ C    E  CP   CS  G C I+ +    C C  GW G  C    +D     P 
Sbjct: 107  GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL--RDFCSANPC 164

Query: 1015 CSGHGTFDVDTQT-CSCHAKWSGEDCSKEV--CSLECGP-------HGRCVGESCSCAAG 1064
             +G        Q  C C   + G  C ++V  C  + GP       H       C C  G
Sbjct: 165  VNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 224

Query: 1065 WSGEFCSVRL--CDAR-CAEHGQC-----KNGT---CLCVSGWNGRHCTL--EGC-PRSC 1110
              G  C +R   C  R C+  G C     K+ T   CLC  G+ G  C +  + C    C
Sbjct: 225  QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVNPDNCVSHQC 284

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
               G C+ D    + C C + W G DC+       +D  + +  G   C +   CQ+ A 
Sbjct: 285  QNGGTCQ-DGLDTYTCLCPETWTGWDCS-------EDVDECEAQGPPHCRNGGTCQNSAG 336

Query: 1171 KSSQLCVS 1178
                +CVS
Sbjct: 337  SFHCVCVS 344



 Score = 70.9 bits (166), Expect = 6e-11
 Identities = 84/302 (27%), Positives = 104/302 (34%), Gaps = 56/302 (18%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ------------ 925
            CP G S         C C  G  G  C     P  C  RG    G CQ            
Sbjct: 204  CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP--CPPRGCSNGGTCQLMPEKDSTFHLC 261

Query: 926  -CNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CPH-- 976
             C PG+ G  C +  D C    C   G C +G     C C   + G  C E +D C    
Sbjct: 262  LCPPGFIGPGCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQG 321

Query: 977  -PTCSGHGFCIEGT----CVCKKGWKGADCGTMDKD--ALQCLPDCSGHGTFD-VDTQTC 1028
             P C   G C        CVC  GW G  C     D  A  C P   G    D V + +C
Sbjct: 322  PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAP---GSTCIDRVGSFSC 378

Query: 1029 SCHAKWSGEDCSKE-VC-SLECGPHGRC-----VGES-CSCAAGWSGEFCSVRLCDARCA 1080
             C    +G  C  E +C S  C    +C      G + C C  G+SG  C   L +   A
Sbjct: 379  LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMA 438

Query: 1081 EHG--QCKNG----------TCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWEC 1126
            + G   C++G           CLC  G+ G  C  +   C       G   +D    + C
Sbjct: 439  QQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC 498

Query: 1127 KC 1128
             C
Sbjct: 499  LC 500



 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 51/182 (28%), Positives = 70/182 (38%), Gaps = 33/182 (18%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGG-------DDCSKSVCPVLCSQRGEYINGECQCNPG 929
            +C NG + +      HC C  G+GG       DDC  + C    +      +  C C PG
Sbjct: 324  HCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 383

Query: 930  WKGKECSLRHDECEVPDCNGHGHC----VNGK--CSCVRGYKGKFCGE--IDC------P 975
              G  C L  D C    C+G   C    + G   C C  GY G  C +   +C      P
Sbjct: 384  RTGLLCHL-EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP 442

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD---TQTC 1028
             P C   G C+       C+C  G+ G+ C   + D  +CL      G+  +D   T  C
Sbjct: 443  SP-CEHGGSCLNTPGSFNCLCPPGYTGSRC---EADHNECLSQPCHPGSTCLDLLATFHC 498

Query: 1029 SC 1030
             C
Sbjct: 499  LC 500


>BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein.
          Length = 1044

 Score =  110 bits (264), Expect = 9e-23
 Identities = 96/340 (28%), Positives = 129/340 (37%), Gaps = 77/340 (22%)

Query: 872  EEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP-----VLCSQRGEYIN----- 921
            +  + +CP    G+ + + G C C  G+ GD C +  CP       CSQR +  N     
Sbjct: 269  QNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEE-CPFGSFGFQCSQRCDCHNGGQCS 327

Query: 922  ---GECQCNPGWKGKEC-------SLRHDECEVP-DCNGHG----HCVNGKCSCVRGYKG 966
               G C+C PG+KG  C        L    C +P  C+       H V G C+C  G+ G
Sbjct: 328  PTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSG 387

Query: 967  KFCGEI--------DCPHP-TCSGHGFC--IEGTCVCKKGWKGADC------GTMDKDAL 1009
              C E          C  P TC     C  I G C C  G+ G  C      GT   +  
Sbjct: 388  HHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNC- 446

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS------------KEVCSLECGPHGRCVGE 1057
              +  C+  GT      +C+C   W G DC+             E C+   G     +  
Sbjct: 447  SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDG 506

Query: 1058 SCSCAAGWSGEFCSVRLCDA----RCAEHGQCKN--------GTCLCVSGWNGRHCTLEG 1105
            SCSC  GW G+ C +   D      C+EH  C +        G C C++GW G  C    
Sbjct: 507  SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCD-ST 565

Query: 1106 CPRSCAGHG---QCRVDNDGR-----WECKCFDGWDGPDC 1137
            CP    G      C  +N G        C+C  G+ GP C
Sbjct: 566  CPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLC 605



 Score =  109 bits (262), Expect = 1e-22
 Identities = 102/338 (30%), Positives = 135/338 (39%), Gaps = 82/338 (24%)

Query: 878  CPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCS-QRG---EYINGE 923
            CP        C  + G C CQPG+ G  C++S         C + C+ Q G     I G 
Sbjct: 362  CPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG 421

Query: 924  CQCNPGWKGKECSLR------HDECE-VPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDC 974
            C C PG+ G+ C++          C  +  CN  G C  V+G C+C  G++G  C  + C
Sbjct: 422  CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDC-TLPC 480

Query: 975  PHPT----------CSGHGFC--IEGTCVCKKGWKGADCGTMDKDA---LQCLP--DCSG 1017
            P  T          C+    C  I+G+C C  GW G  C     D    L C    DCS 
Sbjct: 481  PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSH 540

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSKEV--------CSLECGPH--GRCVGE--SCSCAAGW 1065
                D  T  C C A W+G  C            CS+ C     G C  E  SC CA G+
Sbjct: 541  ADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGF 600

Query: 1066 SGEFCSVRLCDARCAEHGQCK---------------NGTCLCVSGWNGRHCTL------- 1103
             G  C  R+C      HG  +               +G C C+ G++G  C         
Sbjct: 601  RGPLCQ-RICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYF 659

Query: 1104 -EGCPR--SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             + C +  SCA +G C    DG   C+CF GW G DC+
Sbjct: 660  GQDCAQLCSCANNGTCS-PIDG--SCQCFPGWIGKDCS 694



 Score =  105 bits (251), Expect = 3e-21
 Identities = 99/323 (30%), Positives = 123/323 (38%), Gaps = 76/323 (23%)

Query: 886  GECLMG------HCQ--CQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS- 936
            GECL        +C+  C PG  G  C    CP        +I GEC C PGW G  C+ 
Sbjct: 202  GECLCAPGYTGVYCEELCPPGSHGAHCELR-CPCQNGGTCHHITGECACPPGWTGAVCAQ 260

Query: 937  -----LRHDECEVPDCNGH--GHC--VNGKCSCVRGYKGKFCGEIDCPHPT--------- 978
                      C   DC  H  G C  V G+C C  GY G  C E +CP  +         
Sbjct: 261  PCPPGTFGQNCS-QDCPCHHGGQCDHVTGQCHCTAGYMGDRCQE-ECPFGSFGFQCSQRC 318

Query: 979  -CSGHGFC--IEGTCVCKKGWKGADC-GTMDKDALQ---C-LP-DCSGHGTFDVD--TQT 1027
             C   G C    G C C+ G+KG  C   +  + L    C LP  C    T      T  
Sbjct: 319  DCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA 378

Query: 1028 CSCHAKWSGEDCSK--------EVCSLEC----GPHGRCVGESCSCAAGWSGEFCSVRL- 1074
            C+C   WSG  C++        + C L C    G     +   C+CA G+ GE C+V   
Sbjct: 379  CTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCA 438

Query: 1075 -------CDARCA--EHGQCK--NGTCLCVSGWNGRHCTLE--------GCPRSC-AGHG 1114
                   C + C+    G C   +G+C C  GW G  CTL          C  SC   +G
Sbjct: 439  AGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 498

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
                  DG   C C  GW G  C
Sbjct: 499  AACSPIDG--SCSCTPGWLGDTC 519



 Score =  104 bits (250), Expect = 4e-21
 Identities = 99/323 (30%), Positives = 124/323 (38%), Gaps = 78/323 (24%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSV--------CPVLCS-QRGEYIN---GEC 924
            C   C   G C+    C C+PG+GG DCS           C   C  Q G   N   G C
Sbjct: 103  CTEECV-HGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGAC 161

Query: 925  QCNPGWKGKECSL-----RHDE-CEVPDCNGHGHCVN---GKCSCVRGYKGKFCGEIDCP 975
             C  G++G  C        H + C++P    HG   +   G+C C  GY G +C E+ CP
Sbjct: 162  VCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEEL-CP 220

Query: 976  HPT----------CSGHGFC--IEGTCVCKKGWKGADC------GTMDKDALQCLPDCSG 1017
              +          C   G C  I G C C  GW GA C      GT  ++  Q  P C  
Sbjct: 221  PGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCP-CHH 279

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSKEV--------CSLECGPH--GRC--VGESCSCAAGW 1065
             G  D  T  C C A + G+ C +E         CS  C  H  G+C     +C C  G+
Sbjct: 280  GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQCSPTTGACECEPGY 339

Query: 1066 SGEFCSVRLC-----DARCAEHGQCK----------NGTCLCVSGWNGRHCTLEGCPRSC 1110
             G  C  RLC        C     C            G C C  GW+G HC  E CP   
Sbjct: 340  KGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCN-ESCPVGY 398

Query: 1111 AGHGQCRVDNDGRWECKCFDGWD 1133
             G G C++       C C +G D
Sbjct: 399  YGDG-CQL------PCTCQNGAD 414



 Score =  100 bits (240), Expect = 7e-20
 Identities = 98/334 (29%), Positives = 127/334 (38%), Gaps = 84/334 (25%)

Query: 882  CSGKGEC--LMGHCQCQPGFGGDDCSKSVCP-----VLCSQRGEY--------INGECQC 926
            C+    C  + G C C PG+ GD C    CP     + CS+  +         + G C C
Sbjct: 495  CANGAACSPIDGSCSCTPGWLGDTCELP-CPDGTFGLNCSEHCDCSHADGCDPVTGHCCC 553

Query: 927  NPGWKGKECSLR------HDECEVP-DCNGHGHCV--NGKCSCVRGYKGKFCGEIDCPHP 977
              GW G  C            C V   C   G C   +G C C  G++G  C  I CP P
Sbjct: 554  LAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRI-CP-P 611

Query: 978  TCSGHG------FC---------IEGTCVCKKGWKGADC------GTMDKDALQCLPDCS 1016
               GHG       C         I G C C  G+ GA C      G   +D  Q L  C+
Sbjct: 612  GFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQ-LCSCA 670

Query: 1017 GHGTFDVDTQTCSCHAKWSGEDCSKE--------VCSLECGPHG--RCVGE--SCSCAAG 1064
             +GT      +C C   W G+DCS+          C   C  H    C  E  +C C  G
Sbjct: 671  NNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPG 730

Query: 1065 WSGEFCSVRLCDAR-----CAEHGQCKNGT--------CLCVSGWNGRHCTLEGCPRSCA 1111
            W+G FC+ R C A      C    QC+NG         C C +G+ G+HC  + C     
Sbjct: 731  WTGLFCTQR-CPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCE-QRCAPGTF 788

Query: 1112 GHG---QCRVDNDGRWE-----CKCFDGWDGPDC 1137
            G+G    C   N+   +     C C  G+ G  C
Sbjct: 789  GYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRC 822



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 96/340 (28%), Positives = 129/340 (37%), Gaps = 88/340 (25%)

Query: 879  PNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCSQRG----EYINGEC 924
            P  C    +C  + G C C PGF G+ C+ S         C  +CS         ++G C
Sbjct: 406  PCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 465

Query: 925  QCNPGWKGKECSLRHDE------C-EVPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDCP 975
             C  GW+G +C+L          C E   C     C  ++G CSC  G+ G  C E+ CP
Sbjct: 466  TCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC-ELPCP 524

Query: 976  HPT----CSGHGFC--------IEGTCVCKKGWKGADCGTM---DKDALQCLPDCS--GH 1018
              T    CS H  C        + G C C  GW G  C +     +    C   CS    
Sbjct: 525  DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENG 584

Query: 1019 GTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG------RCVGES---------CSCAA 1063
            G+   +  +C C   + G  C + +C      HG       CV  S         C C  
Sbjct: 585  GSCSPEDGSCECAPGFRGPLCQR-ICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLP 643

Query: 1064 GWSGEFCS------------VRLCDARCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPR- 1108
            G+SG  C+             +LC   CA +G C   +G+C C  GW G+ C+ + CP  
Sbjct: 644  GFSGALCNQVCAGGYFGQDCAQLCS--CANNGTCSPIDGSCQCFPGWIGKDCS-QACPPG 700

Query: 1109 ----------SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                      SC     C  + DG   C C  GW G  CT
Sbjct: 701  FWGPACFHACSCHNGASCSAE-DGA--CHCTPGWTGLFCT 737



 Score = 70.9 bits (166), Expect = 6e-11
 Identities = 63/210 (30%), Positives = 80/210 (38%), Gaps = 41/210 (19%)

Query: 878  CPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCS--QRGEY--INGE 923
            CP        C  + G C+C PGF G  C++          C  LCS    G    I+G 
Sbjct: 622  CPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGS 681

Query: 924  CQCNPGWKGKECS------LRHDEC-EVPDCNGHGHC--VNGKCSCVRGYKGKFCGE--- 971
            CQC PGW GK+CS           C     C+    C   +G C C  G+ G FC +   
Sbjct: 682  CQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCP 741

Query: 972  -----IDCPHP-TCSGHGFC--IEGTCVCKKGWKGADC------GTMDKDALQCLPDCSG 1017
                  DC     C     C  I G C C+ G+ G  C      GT      Q L +C  
Sbjct: 742  AAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQ-LCECMN 800

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSKEVCSLE 1047
            + T D  T TC C   + G  C +    +E
Sbjct: 801  NSTCDHVTGTCYCSPGFKGIRCDQAALMME 830



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 55/162 (33%), Positives = 66/162 (40%), Gaps = 37/162 (22%)

Query: 1011 CLPDCSG---HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPH--GRC----------V 1055
            C+P C+    HG   V   TC C   W G DCS    S   GPH   RC          +
Sbjct: 99   CIPLCTEECVHGRC-VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPI 157

Query: 1056 GESCSCAAGWSG----EFCSV----RLCDARC-AEHG-QC--KNGTCLCVSGWNGRHCTL 1103
              +C CAAG+ G    E C+     + C   C   HG  C  + G CLC  G+ G +C  
Sbjct: 158  TGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCE- 216

Query: 1104 EGCPRSCAG-HGQ--CRVDNDG-----RWECKCFDGWDGPDC 1137
            E CP    G H +  C   N G       EC C  GW G  C
Sbjct: 217  ELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVC 258



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 8/50 (16%)

Query: 1092 CVSGW--NGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            C  G+  NG  C +  C   C  HG+C V  D    C C  GW GPDC++
Sbjct: 88   CCPGYYENGDFC-IPLCTEECV-HGRC-VSPD---TCHCEPGWGGPDCSS 131


>BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein.
          Length = 1044

 Score =  110 bits (264), Expect = 9e-23
 Identities = 96/340 (28%), Positives = 129/340 (37%), Gaps = 77/340 (22%)

Query: 872  EEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP-----VLCSQRGEYIN----- 921
            +  + +CP    G+ + + G C C  G+ GD C +  CP       CSQR +  N     
Sbjct: 269  QNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEE-CPFGSFGFQCSQRCDCHNGGQCS 327

Query: 922  ---GECQCNPGWKGKEC-------SLRHDECEVP-DCNGHG----HCVNGKCSCVRGYKG 966
               G C+C PG+KG  C        L    C +P  C+       H V G C+C  G+ G
Sbjct: 328  PTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSG 387

Query: 967  KFCGEI--------DCPHP-TCSGHGFC--IEGTCVCKKGWKGADC------GTMDKDAL 1009
              C E          C  P TC     C  I G C C  G+ G  C      GT   +  
Sbjct: 388  HHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNC- 446

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS------------KEVCSLECGPHGRCVGE 1057
              +  C+  GT      +C+C   W G DC+             E C+   G     +  
Sbjct: 447  SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDG 506

Query: 1058 SCSCAAGWSGEFCSVRLCDA----RCAEHGQCKN--------GTCLCVSGWNGRHCTLEG 1105
            SCSC  GW G+ C +   D      C+EH  C +        G C C++GW G  C    
Sbjct: 507  SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCD-ST 565

Query: 1106 CPRSCAGHG---QCRVDNDGR-----WECKCFDGWDGPDC 1137
            CP    G      C  +N G        C+C  G+ GP C
Sbjct: 566  CPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLC 605



 Score =  109 bits (262), Expect = 1e-22
 Identities = 102/338 (30%), Positives = 135/338 (39%), Gaps = 82/338 (24%)

Query: 878  CPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCS-QRG---EYINGE 923
            CP        C  + G C CQPG+ G  C++S         C + C+ Q G     I G 
Sbjct: 362  CPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG 421

Query: 924  CQCNPGWKGKECSLR------HDECE-VPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDC 974
            C C PG+ G+ C++          C  +  CN  G C  V+G C+C  G++G  C  + C
Sbjct: 422  CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDC-TLPC 480

Query: 975  PHPT----------CSGHGFC--IEGTCVCKKGWKGADCGTMDKDA---LQCLP--DCSG 1017
            P  T          C+    C  I+G+C C  GW G  C     D    L C    DCS 
Sbjct: 481  PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSH 540

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSKEV--------CSLECGPH--GRCVGE--SCSCAAGW 1065
                D  T  C C A W+G  C            CS+ C     G C  E  SC CA G+
Sbjct: 541  ADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGF 600

Query: 1066 SGEFCSVRLCDARCAEHGQCK---------------NGTCLCVSGWNGRHCTL------- 1103
             G  C  R+C      HG  +               +G C C+ G++G  C         
Sbjct: 601  RGPLCQ-RICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYF 659

Query: 1104 -EGCPR--SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             + C +  SCA +G C    DG   C+CF GW G DC+
Sbjct: 660  GQDCAQLCSCANNGTCS-PIDG--SCQCFPGWIGKDCS 694



 Score =  105 bits (251), Expect = 3e-21
 Identities = 99/323 (30%), Positives = 123/323 (38%), Gaps = 76/323 (23%)

Query: 886  GECLMG------HCQ--CQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS- 936
            GECL        +C+  C PG  G  C    CP        +I GEC C PGW G  C+ 
Sbjct: 202  GECLCAPGYTGVYCEELCPPGSHGAHCELR-CPCQNGGTCHHITGECACPPGWTGAVCAQ 260

Query: 937  -----LRHDECEVPDCNGH--GHC--VNGKCSCVRGYKGKFCGEIDCPHPT--------- 978
                      C   DC  H  G C  V G+C C  GY G  C E +CP  +         
Sbjct: 261  PCPPGTFGQNCS-QDCPCHHGGQCDHVTGQCHCTAGYMGDRCQE-ECPFGSFGFQCSQRC 318

Query: 979  -CSGHGFC--IEGTCVCKKGWKGADC-GTMDKDALQ---C-LP-DCSGHGTFDVD--TQT 1027
             C   G C    G C C+ G+KG  C   +  + L    C LP  C    T      T  
Sbjct: 319  DCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA 378

Query: 1028 CSCHAKWSGEDCSK--------EVCSLEC----GPHGRCVGESCSCAAGWSGEFCSVRL- 1074
            C+C   WSG  C++        + C L C    G     +   C+CA G+ GE C+V   
Sbjct: 379  CTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCA 438

Query: 1075 -------CDARCA--EHGQCK--NGTCLCVSGWNGRHCTLE--------GCPRSC-AGHG 1114
                   C + C+    G C   +G+C C  GW G  CTL          C  SC   +G
Sbjct: 439  AGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 498

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
                  DG   C C  GW G  C
Sbjct: 499  AACSPIDG--SCSCTPGWLGDTC 519



 Score =  104 bits (250), Expect = 4e-21
 Identities = 99/323 (30%), Positives = 124/323 (38%), Gaps = 78/323 (24%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSV--------CPVLCS-QRGEYIN---GEC 924
            C   C   G C+    C C+PG+GG DCS           C   C  Q G   N   G C
Sbjct: 103  CTEECV-HGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGAC 161

Query: 925  QCNPGWKGKECSL-----RHDE-CEVPDCNGHGHCVN---GKCSCVRGYKGKFCGEIDCP 975
             C  G++G  C        H + C++P    HG   +   G+C C  GY G +C E+ CP
Sbjct: 162  VCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEEL-CP 220

Query: 976  HPT----------CSGHGFC--IEGTCVCKKGWKGADC------GTMDKDALQCLPDCSG 1017
              +          C   G C  I G C C  GW GA C      GT  ++  Q  P C  
Sbjct: 221  PGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCP-CHH 279

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSKEV--------CSLECGPH--GRC--VGESCSCAAGW 1065
             G  D  T  C C A + G+ C +E         CS  C  H  G+C     +C C  G+
Sbjct: 280  GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQCSPTTGACECEPGY 339

Query: 1066 SGEFCSVRLC-----DARCAEHGQCK----------NGTCLCVSGWNGRHCTLEGCPRSC 1110
             G  C  RLC        C     C            G C C  GW+G HC  E CP   
Sbjct: 340  KGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCN-ESCPVGY 398

Query: 1111 AGHGQCRVDNDGRWECKCFDGWD 1133
             G G C++       C C +G D
Sbjct: 399  YGDG-CQL------PCTCQNGAD 414



 Score =  100 bits (240), Expect = 7e-20
 Identities = 98/334 (29%), Positives = 127/334 (38%), Gaps = 84/334 (25%)

Query: 882  CSGKGEC--LMGHCQCQPGFGGDDCSKSVCP-----VLCSQRGEY--------INGECQC 926
            C+    C  + G C C PG+ GD C    CP     + CS+  +         + G C C
Sbjct: 495  CANGAACSPIDGSCSCTPGWLGDTCELP-CPDGTFGLNCSEHCDCSHADGCDPVTGHCCC 553

Query: 927  NPGWKGKECSLR------HDECEVP-DCNGHGHCV--NGKCSCVRGYKGKFCGEIDCPHP 977
              GW G  C            C V   C   G C   +G C C  G++G  C  I CP P
Sbjct: 554  LAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRI-CP-P 611

Query: 978  TCSGHG------FC---------IEGTCVCKKGWKGADC------GTMDKDALQCLPDCS 1016
               GHG       C         I G C C  G+ GA C      G   +D  Q L  C+
Sbjct: 612  GFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQ-LCSCA 670

Query: 1017 GHGTFDVDTQTCSCHAKWSGEDCSKE--------VCSLECGPHG--RCVGE--SCSCAAG 1064
             +GT      +C C   W G+DCS+          C   C  H    C  E  +C C  G
Sbjct: 671  NNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPG 730

Query: 1065 WSGEFCSVRLCDAR-----CAEHGQCKNGT--------CLCVSGWNGRHCTLEGCPRSCA 1111
            W+G FC+ R C A      C    QC+NG         C C +G+ G+HC  + C     
Sbjct: 731  WTGLFCTQR-CPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCE-QRCAPGTF 788

Query: 1112 GHG---QCRVDNDGRWE-----CKCFDGWDGPDC 1137
            G+G    C   N+   +     C C  G+ G  C
Sbjct: 789  GYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRC 822



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 96/340 (28%), Positives = 129/340 (37%), Gaps = 88/340 (25%)

Query: 879  PNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCSQRG----EYINGEC 924
            P  C    +C  + G C C PGF G+ C+ S         C  +CS         ++G C
Sbjct: 406  PCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 465

Query: 925  QCNPGWKGKECSLRHDE------C-EVPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDCP 975
             C  GW+G +C+L          C E   C     C  ++G CSC  G+ G  C E+ CP
Sbjct: 466  TCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC-ELPCP 524

Query: 976  HPT----CSGHGFC--------IEGTCVCKKGWKGADCGTM---DKDALQCLPDCS--GH 1018
              T    CS H  C        + G C C  GW G  C +     +    C   CS    
Sbjct: 525  DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENG 584

Query: 1019 GTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG------RCVGES---------CSCAA 1063
            G+   +  +C C   + G  C + +C      HG       CV  S         C C  
Sbjct: 585  GSCSPEDGSCECAPGFRGPLCQR-ICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLP 643

Query: 1064 GWSGEFCS------------VRLCDARCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPR- 1108
            G+SG  C+             +LC   CA +G C   +G+C C  GW G+ C+ + CP  
Sbjct: 644  GFSGALCNQVCAGGYFGQDCAQLCS--CANNGTCSPIDGSCQCFPGWIGKDCS-QACPPG 700

Query: 1109 ----------SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                      SC     C  + DG   C C  GW G  CT
Sbjct: 701  FWGPACFHACSCHNGASCSAE-DGA--CHCTPGWTGLFCT 737



 Score = 70.9 bits (166), Expect = 6e-11
 Identities = 63/210 (30%), Positives = 80/210 (38%), Gaps = 41/210 (19%)

Query: 878  CPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCS--QRGEY--INGE 923
            CP        C  + G C+C PGF G  C++          C  LCS    G    I+G 
Sbjct: 622  CPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGS 681

Query: 924  CQCNPGWKGKECS------LRHDEC-EVPDCNGHGHC--VNGKCSCVRGYKGKFCGE--- 971
            CQC PGW GK+CS           C     C+    C   +G C C  G+ G FC +   
Sbjct: 682  CQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCP 741

Query: 972  -----IDCPHP-TCSGHGFC--IEGTCVCKKGWKGADC------GTMDKDALQCLPDCSG 1017
                  DC     C     C  I G C C+ G+ G  C      GT      Q L +C  
Sbjct: 742  AAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQ-LCECMN 800

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSKEVCSLE 1047
            + T D  T TC C   + G  C +    +E
Sbjct: 801  NSTCDHVTGTCYCSPGFKGIRCDQAALMME 830



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 55/162 (33%), Positives = 66/162 (40%), Gaps = 37/162 (22%)

Query: 1011 CLPDCSG---HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPH--GRC----------V 1055
            C+P C+    HG   V   TC C   W G DCS    S   GPH   RC          +
Sbjct: 99   CIPLCTEECVHGRC-VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPI 157

Query: 1056 GESCSCAAGWSG----EFCSV----RLCDARC-AEHG-QC--KNGTCLCVSGWNGRHCTL 1103
              +C CAAG+ G    E C+     + C   C   HG  C  + G CLC  G+ G +C  
Sbjct: 158  TGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCE- 216

Query: 1104 EGCPRSCAG-HGQ--CRVDNDG-----RWECKCFDGWDGPDC 1137
            E CP    G H +  C   N G       EC C  GW G  C
Sbjct: 217  ELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVC 258



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 8/50 (16%)

Query: 1092 CVSGW--NGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            C  G+  NG  C +  C   C  HG+C V  D    C C  GW GPDC++
Sbjct: 88   CCPGYYENGDFC-IPLCTEECV-HGRC-VSPD---TCHCEPGWGGPDCSS 131


>BC018037-1|AAH18037.1|  379|Homo sapiens WNT inhibitory factor 1
            protein.
          Length = 379

 Score =  110 bits (264), Expect = 9e-23
 Identities = 56/166 (33%), Positives = 75/166 (45%), Gaps = 12/166 (7%)

Query: 941  ECEVPD-CNGHGHCVNGK-CSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWK 997
            + E P  C   G C   + C C  G+ G  C +  C  P C   G C+  G C+C  G+ 
Sbjct: 179  QAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCT-PRCMNGGLCVTPGFCICPPGFY 237

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G +C     D   C   C   GT     + C C     GE C    C   C   G+C+G+
Sbjct: 238  GVNC-----DKANCSTTCFNGGTCFYPGK-CICPPGLEGEQCEISKCPQPCRNGGKCIGK 291

Query: 1058 S-CSCAAGWSGEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHC 1101
            S C C+ G+ G+ CS  +C+  C  HG C +   C C  GW+GRHC
Sbjct: 292  SKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337



 Score =  102 bits (245), Expect = 2e-20
 Identities = 58/167 (34%), Positives = 71/167 (42%), Gaps = 12/167 (7%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            CP GC   G C     C+C  GF G  C K++C   C   G  +  G C C PG+ G  C
Sbjct: 182  CPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNC 241

Query: 936  SLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKK 994
               +  C     NG      GKC C  G +G+ C    CP P C   G CI +  C C K
Sbjct: 242  DKAN--CSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQP-CRNGGKCIGKSKCKCSK 298

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
            G++G  C         C P C  HGT   +   C C   W G  C+K
Sbjct: 299  GYQGDLCSKP-----VCEPGCGAHGTCH-EPNKCQCQEGWHGRHCNK 339



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 58/174 (33%), Positives = 72/174 (41%), Gaps = 14/174 (8%)

Query: 967  KFCGEIDCPHPTCSGHGFCIEGT-CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDT 1025
            K C + +CP   C   GFC E   C C  G+ G  C    + AL C P C  +G   V  
Sbjct: 175  KTCQQAECPGG-CRNGGFCNERRICECPDGFHGPHC----EKAL-CTPRCM-NGGLCVTP 227

Query: 1026 QTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES-CSCAAGWSGEFCSVRLCDARCAEHGQ 1084
              C C   + G +C K  CS  C   G C     C C  G  GE C +  C   C   G+
Sbjct: 228  GFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGK 287

Query: 1085 C-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C     C C  G+ G  C+   C   C  HG C   N    +C+C +GW G  C
Sbjct: 288  CIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPN----KCQCQEGWHGRHC 337



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 57/175 (32%), Positives = 74/175 (42%), Gaps = 16/175 (9%)

Query: 904  CSKSVCPVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVN-GKCSC 960
            C ++ CP  C + G + N    C+C  G+ G  C      C  P C   G CV  G C C
Sbjct: 177  CQQAECPGGC-RNGGFCNERRICECPDGFHGPHCEKAL--C-TPRCMNGGLCVTPGFCIC 232

Query: 961  VRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHG 1019
              G+ G  C + +C   TC   G C   G C+C  G +G  C     +  +C   C   G
Sbjct: 233  PPGFYGVNCDKANCS-TTCFNGGTCFYPGKCICPPGLEGEQC-----EISKCPQPCRNGG 286

Query: 1020 TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC-VGESCSCAAGWSGEFCSVR 1073
               +    C C   + G+ CSK VC   CG HG C     C C  GW G  C+ R
Sbjct: 287  KC-IGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340



 Score = 79.8 bits (188), Expect = 1e-13
 Identities = 41/131 (31%), Positives = 57/131 (43%), Gaps = 7/131 (5%)

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES-CSCAAGWSGE 1068
            +C   C  +G F  + + C C   + G  C K +C+  C   G CV    C C  G+ G 
Sbjct: 181  ECPGGCR-NGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGV 239

Query: 1069 FCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECK 1127
             C    C   C   G C   G C+C  G  G  C +  CP+ C   G+C     G+ +CK
Sbjct: 240  NCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKC----IGKSKCK 295

Query: 1128 CFDGWDGPDCT 1138
            C  G+ G  C+
Sbjct: 296  CSKGYQGDLCS 306



 Score = 62.1 bits (144), Expect = 3e-08
 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 878 CPNGCSGKGECL-MGHCQCQPGFGGDDCSKSVCPVLCSQRGE-YINGECQCNPGWKGKEC 935
           CP  C   G+C+    C+C  G+ GD CSK VC   C   G  +   +CQC  GW G+ C
Sbjct: 278 CPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337

Query: 936 SLRHD 940
           + R++
Sbjct: 338 NKRYE 342


>AY358344-1|AAQ88710.1|  379|Homo sapiens WIF-1 protein.
          Length = 379

 Score =  110 bits (264), Expect = 9e-23
 Identities = 56/166 (33%), Positives = 75/166 (45%), Gaps = 12/166 (7%)

Query: 941  ECEVPD-CNGHGHCVNGK-CSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWK 997
            + E P  C   G C   + C C  G+ G  C +  C  P C   G C+  G C+C  G+ 
Sbjct: 179  QAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCT-PRCMNGGLCVTPGFCICPPGFY 237

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G +C     D   C   C   GT     + C C     GE C    C   C   G+C+G+
Sbjct: 238  GVNC-----DKANCSTTCFNGGTCFYPGK-CICPPGLEGEQCEISKCPQPCRNGGKCIGK 291

Query: 1058 S-CSCAAGWSGEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHC 1101
            S C C+ G+ G+ CS  +C+  C  HG C +   C C  GW+GRHC
Sbjct: 292  SKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337



 Score =  102 bits (245), Expect = 2e-20
 Identities = 58/167 (34%), Positives = 71/167 (42%), Gaps = 12/167 (7%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            CP GC   G C     C+C  GF G  C K++C   C   G  +  G C C PG+ G  C
Sbjct: 182  CPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNC 241

Query: 936  SLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKK 994
               +  C     NG      GKC C  G +G+ C    CP P C   G CI +  C C K
Sbjct: 242  DKAN--CSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQP-CRNGGKCIGKSKCKCSK 298

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
            G++G  C         C P C  HGT   +   C C   W G  C+K
Sbjct: 299  GYQGDLCSKP-----VCEPGCGAHGTCH-EPNKCQCQEGWHGRHCNK 339



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 58/174 (33%), Positives = 72/174 (41%), Gaps = 14/174 (8%)

Query: 967  KFCGEIDCPHPTCSGHGFCIEGT-CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDT 1025
            K C + +CP   C   GFC E   C C  G+ G  C    + AL C P C  +G   V  
Sbjct: 175  KTCQQAECPGG-CRNGGFCNERRICECPDGFHGPHC----EKAL-CTPRCM-NGGLCVTP 227

Query: 1026 QTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES-CSCAAGWSGEFCSVRLCDARCAEHGQ 1084
              C C   + G +C K  CS  C   G C     C C  G  GE C +  C   C   G+
Sbjct: 228  GFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGK 287

Query: 1085 C-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C     C C  G+ G  C+   C   C  HG C   N    +C+C +GW G  C
Sbjct: 288  CIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPN----KCQCQEGWHGRHC 337



 Score = 95.1 bits (226), Expect = 3e-18
 Identities = 57/175 (32%), Positives = 74/175 (42%), Gaps = 16/175 (9%)

Query: 904  CSKSVCPVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVN-GKCSC 960
            C ++ CP  C + G + N    C+C  G+ G  C      C  P C   G CV  G C C
Sbjct: 177  CQQAECPGGC-RNGGFCNERRICECPDGFHGPHCEKAL--C-TPRCMNGGLCVTPGFCIC 232

Query: 961  VRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHG 1019
              G+ G  C + +C   TC   G C   G C+C  G +G  C     +  +C   C   G
Sbjct: 233  PPGFYGVNCDKANCS-TTCFNGGTCFYPGKCICPPGLEGEQC-----EISKCPQPCRNGG 286

Query: 1020 TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC-VGESCSCAAGWSGEFCSVR 1073
               +    C C   + G+ CSK VC   CG HG C     C C  GW G  C+ R
Sbjct: 287  KC-IGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340



 Score = 79.8 bits (188), Expect = 1e-13
 Identities = 41/131 (31%), Positives = 57/131 (43%), Gaps = 7/131 (5%)

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES-CSCAAGWSGE 1068
            +C   C  +G F  + + C C   + G  C K +C+  C   G CV    C C  G+ G 
Sbjct: 181  ECPGGCR-NGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGV 239

Query: 1069 FCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECK 1127
             C    C   C   G C   G C+C  G  G  C +  CP+ C   G+C     G+ +CK
Sbjct: 240  NCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKC----IGKSKCK 295

Query: 1128 CFDGWDGPDCT 1138
            C  G+ G  C+
Sbjct: 296  CSKGYQGDLCS 306



 Score = 62.1 bits (144), Expect = 3e-08
 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 878 CPNGCSGKGECL-MGHCQCQPGFGGDDCSKSVCPVLCSQRGE-YINGECQCNPGWKGKEC 935
           CP  C   G+C+    C+C  G+ GD CSK VC   C   G  +   +CQC  GW G+ C
Sbjct: 278 CPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337

Query: 936 SLRHD 940
           + R++
Sbjct: 338 NKRYE 342


>AL834326-1|CAD38994.1|  626|Homo sapiens hypothetical protein
            protein.
          Length = 626

 Score =  110 bits (264), Expect = 9e-23
 Identities = 96/340 (28%), Positives = 129/340 (37%), Gaps = 77/340 (22%)

Query: 872  EEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP-----VLCSQRGEYIN----- 921
            +  + +CP    G+ + + G C C  G+ GD C +  CP       CSQR +  N     
Sbjct: 20   QNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEE-CPFGSFGFQCSQRCDCHNGGQCS 78

Query: 922  ---GECQCNPGWKGKEC-------SLRHDECEVP-DCNGHG----HCVNGKCSCVRGYKG 966
               G C+C PG+KG  C        L    C +P  C+       H V G C+C  G+ G
Sbjct: 79   PTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSG 138

Query: 967  KFCGEI--------DCPHP-TCSGHGFC--IEGTCVCKKGWKGADC------GTMDKDAL 1009
              C E          C  P TC     C  I G C C  G+ G  C      GT   +  
Sbjct: 139  HHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNC- 197

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS------------KEVCSLECGPHGRCVGE 1057
              +  C+  GT      +C+C   W G DC+             E C+   G     +  
Sbjct: 198  SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDG 257

Query: 1058 SCSCAAGWSGEFCSVRLCDA----RCAEHGQCKN--------GTCLCVSGWNGRHCTLEG 1105
            SCSC  GW G+ C +   D      C+EH  C +        G C C++GW G  C    
Sbjct: 258  SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCD-ST 316

Query: 1106 CPRSCAGHG---QCRVDNDGR-----WECKCFDGWDGPDC 1137
            CP    G      C  +N G        C+C  G+ GP C
Sbjct: 317  CPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLC 356



 Score =  109 bits (262), Expect = 1e-22
 Identities = 102/338 (30%), Positives = 135/338 (39%), Gaps = 82/338 (24%)

Query: 878  CPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCS-QRG---EYINGE 923
            CP        C  + G C CQPG+ G  C++S         C + C+ Q G     I G 
Sbjct: 113  CPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG 172

Query: 924  CQCNPGWKGKECSLR------HDECE-VPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDC 974
            C C PG+ G+ C++          C  +  CN  G C  V+G C+C  G++G  C  + C
Sbjct: 173  CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDC-TLPC 231

Query: 975  PHPT----------CSGHGFC--IEGTCVCKKGWKGADCGTMDKDA---LQCLP--DCSG 1017
            P  T          C+    C  I+G+C C  GW G  C     D    L C    DCS 
Sbjct: 232  PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSH 291

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSKEV--------CSLECGPH--GRCVGE--SCSCAAGW 1065
                D  T  C C A W+G  C            CS+ C     G C  E  SC CA G+
Sbjct: 292  ADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGF 351

Query: 1066 SGEFCSVRLCDARCAEHGQCK---------------NGTCLCVSGWNGRHCTL------- 1103
             G  C  R+C      HG  +               +G C C+ G++G  C         
Sbjct: 352  RGPLCQ-RICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYF 410

Query: 1104 -EGCPR--SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             + C +  SCA +G C    DG   C+CF GW G DC+
Sbjct: 411  GQDCAQLCSCANNGTCS-PIDG--SCQCFPGWIGKDCS 445



 Score = 99.1 bits (236), Expect = 2e-19
 Identities = 97/346 (28%), Positives = 131/346 (37%), Gaps = 88/346 (25%)

Query: 879  PNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCSQRG----EYINGEC 924
            P  C    +C  + G C C PGF G+ C+ S         C  +CS         ++G C
Sbjct: 157  PCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 216

Query: 925  QCNPGWKGKECSLRHDE------C-EVPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDCP 975
             C  GW+G +C+L          C E   C     C  ++G CSC  G+ G  C E+ CP
Sbjct: 217  TCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC-ELPCP 275

Query: 976  HPT----CSGHGFC--------IEGTCVCKKGWKGADCGTM---DKDALQCLPDCS--GH 1018
              T    CS H  C        + G C C  GW G  C +     +    C   CS    
Sbjct: 276  DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENG 335

Query: 1019 GTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG------RCVGES---------CSCAA 1063
            G+   +  +C C   + G  C + +C      HG       CV  S         C C  
Sbjct: 336  GSCSPEDGSCECAPGFRGPLCQR-ICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLP 394

Query: 1064 GWSGEFCS------------VRLCDARCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPR- 1108
            G+SG  C+             +LC   CA +G C   +G+C C  GW G+ C+ + CP  
Sbjct: 395  GFSGALCNQVCAGGYFGQDCAQLCS--CANNGTCSPIDGSCQCFPGWIGKDCS-QACPPG 451

Query: 1109 ----------SCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQI 1144
                      SC     C  + DG   C C  GW G  CT  K  +
Sbjct: 452  FWGPACFHACSCHNGASCSAE-DGA--CHCTPGWTGLFCTQRKPHL 494



 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 38/115 (33%), Positives = 47/115 (40%), Gaps = 23/115 (20%)

Query: 878 CPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCS--QRGEY--INGE 923
           CP        C  + G C+C PGF G  C++          C  LCS    G    I+G 
Sbjct: 373 CPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGS 432

Query: 924 CQCNPGWKGKECS------LRHDEC-EVPDCNGHGHC--VNGKCSCVRGYKGKFC 969
           CQC PGW GK+CS           C     C+    C   +G C C  G+ G FC
Sbjct: 433 CQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFC 487


>AF122922-1|AAD25402.1|  379|Homo sapiens Wnt inhibitory factor-1
            protein.
          Length = 379

 Score =  110 bits (264), Expect = 9e-23
 Identities = 56/166 (33%), Positives = 75/166 (45%), Gaps = 12/166 (7%)

Query: 941  ECEVPD-CNGHGHCVNGK-CSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-GTCVCKKGWK 997
            + E P  C   G C   + C C  G+ G  C +  C  P C   G C+  G C+C  G+ 
Sbjct: 179  QAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCT-PRCMNGGLCVTPGFCICPPGFY 237

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            G +C     D   C   C   GT     + C C     GE C    C   C   G+C+G+
Sbjct: 238  GVNC-----DKANCSTTCFNGGTCFYPGK-CICPPGLEGEQCEISKCPQPCRNGGKCIGK 291

Query: 1058 S-CSCAAGWSGEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHC 1101
            S C C+ G+ G+ CS  +C+  C  HG C +   C C  GW+GRHC
Sbjct: 292  SKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337



 Score =  102 bits (245), Expect = 2e-20
 Identities = 58/167 (34%), Positives = 71/167 (42%), Gaps = 12/167 (7%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            CP GC   G C     C+C  GF G  C K++C   C   G  +  G C C PG+ G  C
Sbjct: 182  CPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNC 241

Query: 936  SLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKK 994
               +  C     NG      GKC C  G +G+ C    CP P C   G CI +  C C K
Sbjct: 242  DKAN--CSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQP-CRNGGKCIGKSKCKCSK 298

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
            G++G  C         C P C  HGT   +   C C   W G  C+K
Sbjct: 299  GYQGDLCSKP-----VCEPGCGAHGTCH-EPNKCQCQEGWHGRHCNK 339



 Score = 97.1 bits (231), Expect = 9e-19
 Identities = 58/174 (33%), Positives = 72/174 (41%), Gaps = 14/174 (8%)

Query: 967  KFCGEIDCPHPTCSGHGFCIEGT-CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDT 1025
            K C + +CP   C   GFC E   C C  G+ G  C    + AL C P C  +G   V  
Sbjct: 175  KTCLQAECPGG-CRNGGFCNERRICECPDGFHGPHC----EKAL-CTPRCM-NGGLCVTP 227

Query: 1026 QTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES-CSCAAGWSGEFCSVRLCDARCAEHGQ 1084
              C C   + G +C K  CS  C   G C     C C  G  GE C +  C   C   G+
Sbjct: 228  GFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGK 287

Query: 1085 C-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C     C C  G+ G  C+   C   C  HG C   N    +C+C +GW G  C
Sbjct: 288  CIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPN----KCQCQEGWHGRHC 337



 Score = 94.3 bits (224), Expect = 6e-18
 Identities = 57/175 (32%), Positives = 74/175 (42%), Gaps = 16/175 (9%)

Query: 904  CSKSVCPVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVN-GKCSC 960
            C ++ CP  C + G + N    C+C  G+ G  C      C  P C   G CV  G C C
Sbjct: 177  CLQAECPGGC-RNGGFCNERRICECPDGFHGPHCEKAL--C-TPRCMNGGLCVTPGFCIC 232

Query: 961  VRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHG 1019
              G+ G  C + +C   TC   G C   G C+C  G +G  C     +  +C   C   G
Sbjct: 233  PPGFYGVNCDKANCS-TTCFNGGTCFYPGKCICPPGLEGEQC-----EISKCPQPCRNGG 286

Query: 1020 TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRC-VGESCSCAAGWSGEFCSVR 1073
               +    C C   + G+ CSK VC   CG HG C     C C  GW G  C+ R
Sbjct: 287  KC-IGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340



 Score = 79.8 bits (188), Expect = 1e-13
 Identities = 43/134 (32%), Positives = 59/134 (44%), Gaps = 10/134 (7%)

Query: 1011 CLP-DCSG---HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES-CSCAAGW 1065
            CL  +C G   +G F  + + C C   + G  C K +C+  C   G CV    C C  G+
Sbjct: 177  CLQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGF 236

Query: 1066 SGEFCSVRLCDARCAEHGQC-KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRW 1124
             G  C    C   C   G C   G C+C  G  G  C +  CP+ C   G+C     G+ 
Sbjct: 237  YGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKC----IGKS 292

Query: 1125 ECKCFDGWDGPDCT 1138
            +CKC  G+ G  C+
Sbjct: 293  KCKCSKGYQGDLCS 306



 Score = 62.1 bits (144), Expect = 3e-08
 Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 878 CPNGCSGKGECL-MGHCQCQPGFGGDDCSKSVCPVLCSQRGE-YINGECQCNPGWKGKEC 935
           CP  C   G+C+    C+C  G+ GD CSK VC   C   G  +   +CQC  GW G+ C
Sbjct: 278 CPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337

Query: 936 SLRHD 940
           + R++
Sbjct: 338 NKRYE 342


>AB058677-1|BAB47410.1|  969|Homo sapiens MEGF11 protein (KIAA1781)
            protein.
          Length = 969

 Score =  110 bits (264), Expect = 9e-23
 Identities = 96/340 (28%), Positives = 129/340 (37%), Gaps = 77/340 (22%)

Query: 872  EEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP-----VLCSQRGEYIN----- 921
            +  + +CP    G+ + + G C C  G+ GD C +  CP       CSQR +  N     
Sbjct: 194  QNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEE-CPFGSFGFQCSQRCDCHNGGQCS 252

Query: 922  ---GECQCNPGWKGKEC-------SLRHDECEVP-DCNGHG----HCVNGKCSCVRGYKG 966
               G C+C PG+KG  C        L    C +P  C+       H V G C+C  G+ G
Sbjct: 253  PTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSG 312

Query: 967  KFCGEI--------DCPHP-TCSGHGFC--IEGTCVCKKGWKGADC------GTMDKDAL 1009
              C E          C  P TC     C  I G C C  G+ G  C      GT   +  
Sbjct: 313  HHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNC- 371

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS------------KEVCSLECGPHGRCVGE 1057
              +  C+  GT      +C+C   W G DC+             E C+   G     +  
Sbjct: 372  SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDG 431

Query: 1058 SCSCAAGWSGEFCSVRLCDA----RCAEHGQCKN--------GTCLCVSGWNGRHCTLEG 1105
            SCSC  GW G+ C +   D      C+EH  C +        G C C++GW G  C    
Sbjct: 432  SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCD-ST 490

Query: 1106 CPRSCAGHG---QCRVDNDGR-----WECKCFDGWDGPDC 1137
            CP    G      C  +N G        C+C  G+ GP C
Sbjct: 491  CPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLC 530



 Score =  109 bits (262), Expect = 1e-22
 Identities = 102/338 (30%), Positives = 135/338 (39%), Gaps = 82/338 (24%)

Query: 878  CPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCS-QRG---EYINGE 923
            CP        C  + G C CQPG+ G  C++S         C + C+ Q G     I G 
Sbjct: 287  CPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG 346

Query: 924  CQCNPGWKGKECSLR------HDECE-VPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDC 974
            C C PG+ G+ C++          C  +  CN  G C  V+G C+C  G++G  C  + C
Sbjct: 347  CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDC-TLPC 405

Query: 975  PHPT----------CSGHGFC--IEGTCVCKKGWKGADCGTMDKDA---LQCLP--DCSG 1017
            P  T          C+    C  I+G+C C  GW G  C     D    L C    DCS 
Sbjct: 406  PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSH 465

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSKEV--------CSLECGPH--GRCVGE--SCSCAAGW 1065
                D  T  C C A W+G  C            CS+ C     G C  E  SC CA G+
Sbjct: 466  ADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGF 525

Query: 1066 SGEFCSVRLCDARCAEHGQCK---------------NGTCLCVSGWNGRHCTL------- 1103
             G  C  R+C      HG  +               +G C C+ G++G  C         
Sbjct: 526  RGPLCQ-RICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYF 584

Query: 1104 -EGCPR--SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             + C +  SCA +G C    DG   C+CF GW G DC+
Sbjct: 585  GQDCAQLCSCANNGTCS-PIDG--SCQCFPGWIGKDCS 619



 Score =  105 bits (251), Expect = 3e-21
 Identities = 99/323 (30%), Positives = 123/323 (38%), Gaps = 76/323 (23%)

Query: 886  GECLMG------HCQ--CQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS- 936
            GECL        +C+  C PG  G  C    CP        +I GEC C PGW G  C+ 
Sbjct: 127  GECLCAPGYTGVYCEELCPPGSHGAHCELR-CPCQNGGTCHHITGECACPPGWTGAVCAQ 185

Query: 937  -----LRHDECEVPDCNGH--GHC--VNGKCSCVRGYKGKFCGEIDCPHPT--------- 978
                      C   DC  H  G C  V G+C C  GY G  C E +CP  +         
Sbjct: 186  PCPPGTFGQNCS-QDCPCHHGGQCDHVTGQCHCTAGYMGDRCQE-ECPFGSFGFQCSQRC 243

Query: 979  -CSGHGFC--IEGTCVCKKGWKGADC-GTMDKDALQ---C-LP-DCSGHGTFDVD--TQT 1027
             C   G C    G C C+ G+KG  C   +  + L    C LP  C    T      T  
Sbjct: 244  DCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA 303

Query: 1028 CSCHAKWSGEDCSK--------EVCSLEC----GPHGRCVGESCSCAAGWSGEFCSVRL- 1074
            C+C   WSG  C++        + C L C    G     +   C+CA G+ GE C+V   
Sbjct: 304  CTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCA 363

Query: 1075 -------CDARCA--EHGQCK--NGTCLCVSGWNGRHCTLE--------GCPRSC-AGHG 1114
                   C + C+    G C   +G+C C  GW G  CTL          C  SC   +G
Sbjct: 364  AGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 423

Query: 1115 QCRVDNDGRWECKCFDGWDGPDC 1137
                  DG   C C  GW G  C
Sbjct: 424  AACSPIDG--SCSCTPGWLGDTC 444



 Score =  104 bits (250), Expect = 4e-21
 Identities = 99/323 (30%), Positives = 124/323 (38%), Gaps = 78/323 (24%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSV--------CPVLCS-QRGEYIN---GEC 924
            C   C   G C+    C C+PG+GG DCS           C   C  Q G   N   G C
Sbjct: 28   CTEECV-HGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGAC 86

Query: 925  QCNPGWKGKECSL-----RHDE-CEVPDCNGHGHCVN---GKCSCVRGYKGKFCGEIDCP 975
             C  G++G  C        H + C++P    HG   +   G+C C  GY G +C E+ CP
Sbjct: 87   VCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEEL-CP 145

Query: 976  HPT----------CSGHGFC--IEGTCVCKKGWKGADC------GTMDKDALQCLPDCSG 1017
              +          C   G C  I G C C  GW GA C      GT  ++  Q  P C  
Sbjct: 146  PGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCP-CHH 204

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSKEV--------CSLECGPH--GRC--VGESCSCAAGW 1065
             G  D  T  C C A + G+ C +E         CS  C  H  G+C     +C C  G+
Sbjct: 205  GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQRCDCHNGGQCSPTTGACECEPGY 264

Query: 1066 SGEFCSVRLC-----DARCAEHGQCK----------NGTCLCVSGWNGRHCTLEGCPRSC 1110
             G  C  RLC        C     C            G C C  GW+G HC  E CP   
Sbjct: 265  KGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCN-ESCPVGY 323

Query: 1111 AGHGQCRVDNDGRWECKCFDGWD 1133
             G G C++       C C +G D
Sbjct: 324  YGDG-CQL------PCTCQNGAD 339



 Score =  100 bits (240), Expect = 7e-20
 Identities = 98/334 (29%), Positives = 127/334 (38%), Gaps = 84/334 (25%)

Query: 882  CSGKGEC--LMGHCQCQPGFGGDDCSKSVCP-----VLCSQRGEY--------INGECQC 926
            C+    C  + G C C PG+ GD C    CP     + CS+  +         + G C C
Sbjct: 420  CANGAACSPIDGSCSCTPGWLGDTCELP-CPDGTFGLNCSEHCDCSHADGCDPVTGHCCC 478

Query: 927  NPGWKGKECSLR------HDECEVP-DCNGHGHCV--NGKCSCVRGYKGKFCGEIDCPHP 977
              GW G  C            C V   C   G C   +G C C  G++G  C  I CP P
Sbjct: 479  LAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRI-CP-P 536

Query: 978  TCSGHG------FC---------IEGTCVCKKGWKGADC------GTMDKDALQCLPDCS 1016
               GHG       C         I G C C  G+ GA C      G   +D  Q L  C+
Sbjct: 537  GFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQ-LCSCA 595

Query: 1017 GHGTFDVDTQTCSCHAKWSGEDCSKE--------VCSLECGPHG--RCVGE--SCSCAAG 1064
             +GT      +C C   W G+DCS+          C   C  H    C  E  +C C  G
Sbjct: 596  NNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPG 655

Query: 1065 WSGEFCSVRLCDAR-----CAEHGQCKNGT--------CLCVSGWNGRHCTLEGCPRSCA 1111
            W+G FC+ R C A      C    QC+NG         C C +G+ G+HC  + C     
Sbjct: 656  WTGLFCTQR-CPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCE-QRCAPGTF 713

Query: 1112 GHG---QCRVDNDGRWE-----CKCFDGWDGPDC 1137
            G+G    C   N+   +     C C  G+ G  C
Sbjct: 714  GYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRC 747



 Score = 97.9 bits (233), Expect = 5e-19
 Identities = 96/340 (28%), Positives = 129/340 (37%), Gaps = 88/340 (25%)

Query: 879  PNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCSQRG----EYINGEC 924
            P  C    +C  + G C C PGF G+ C+ S         C  +CS         ++G C
Sbjct: 331  PCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 390

Query: 925  QCNPGWKGKECSLRHDE------C-EVPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDCP 975
             C  GW+G +C+L          C E   C     C  ++G CSC  G+ G  C E+ CP
Sbjct: 391  TCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC-ELPCP 449

Query: 976  HPT----CSGHGFC--------IEGTCVCKKGWKGADCGTM---DKDALQCLPDCS--GH 1018
              T    CS H  C        + G C C  GW G  C +     +    C   CS    
Sbjct: 450  DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENG 509

Query: 1019 GTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG------RCVGES---------CSCAA 1063
            G+   +  +C C   + G  C + +C      HG       CV  S         C C  
Sbjct: 510  GSCSPEDGSCECAPGFRGPLCQR-ICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLP 568

Query: 1064 GWSGEFCS------------VRLCDARCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPR- 1108
            G+SG  C+             +LC   CA +G C   +G+C C  GW G+ C+ + CP  
Sbjct: 569  GFSGALCNQVCAGGYFGQDCAQLCS--CANNGTCSPIDGSCQCFPGWIGKDCS-QACPPG 625

Query: 1109 ----------SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                      SC     C  + DG   C C  GW G  CT
Sbjct: 626  FWGPACFHACSCHNGASCSAE-DGA--CHCTPGWTGLFCT 662



 Score = 70.9 bits (166), Expect = 6e-11
 Identities = 63/210 (30%), Positives = 80/210 (38%), Gaps = 41/210 (19%)

Query: 878  CPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSV--------CPVLCS--QRGEY--INGE 923
            CP        C  + G C+C PGF G  C++          C  LCS    G    I+G 
Sbjct: 547  CPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGS 606

Query: 924  CQCNPGWKGKECS------LRHDEC-EVPDCNGHGHC--VNGKCSCVRGYKGKFCGE--- 971
            CQC PGW GK+CS           C     C+    C   +G C C  G+ G FC +   
Sbjct: 607  CQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCP 666

Query: 972  -----IDCPHP-TCSGHGFC--IEGTCVCKKGWKGADC------GTMDKDALQCLPDCSG 1017
                  DC     C     C  I G C C+ G+ G  C      GT      Q L +C  
Sbjct: 667  AAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQ-LCECMN 725

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSKEVCSLE 1047
            + T D  T TC C   + G  C +    +E
Sbjct: 726  NSTCDHVTGTCYCSPGFKGIRCDQAALMME 755



 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 54/159 (33%), Positives = 64/159 (40%), Gaps = 35/159 (22%)

Query: 1011 CLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPH--GRC----------VGES 1058
            C  +C  HG   V   TC C   W G DCS    S   GPH   RC          +  +
Sbjct: 28   CTEECV-HGRC-VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGA 85

Query: 1059 CSCAAGWSG----EFCSV----RLCDARC-AEHG-QC--KNGTCLCVSGWNGRHCTLEGC 1106
            C CAAG+ G    E C+     + C   C   HG  C  + G CLC  G+ G +C  E C
Sbjct: 86   CVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCE-ELC 144

Query: 1107 PRSCAG-HGQ--CRVDNDG-----RWECKCFDGWDGPDC 1137
            P    G H +  C   N G       EC C  GW G  C
Sbjct: 145  PPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVC 183



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 11/76 (14%)

Query: 1074 LCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRS-----CAGHGQCR---VDNDGRW 1124
            LC   C  HG+C +  TC C  GW G  C+  GC        C+   QC+   + N    
Sbjct: 27   LCTEECV-HGRCVSPDTCHCEPGWGGPDCS-SGCDSDHWGPHCSNRCQCQNGALCNPITG 84

Query: 1125 ECKCFDGWDGPDCTTL 1140
             C C  G+ G  C  L
Sbjct: 85   ACVCAAGFRGWRCEEL 100


>Z99715-2|CAI19286.1| 1299|Homo sapiens tenascin N protein.
          Length = 1299

 Score =  108 bits (260), Expect = 3e-22
 Identities = 46/123 (37%), Positives = 59/123 (47%), Gaps = 5/123 (4%)

Query: 1015 CSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL 1074
            CSGHGTF ++T +C C     G  C +  C   C  HGRCV   C C   + G  C    
Sbjct: 142  CSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPA 201

Query: 1075 CDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
            C   C+ HG+C  G C C   +    C+ + CP  C+GHG C        EC C +G+ G
Sbjct: 202  CPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTG-----ECYCEEGFTG 256

Query: 1135 PDC 1137
             DC
Sbjct: 257  LDC 259



 Score =  106 bits (254), Expect = 1e-21
 Identities = 47/122 (38%), Positives = 63/122 (51%), Gaps = 6/122 (4%)

Query: 882  CSGKGECLMG--HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH 939
            CSG G   +    C C+ G  G  C +  CP  CS  G  ++G C C+  + G +C   +
Sbjct: 142  CSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCG--Y 199

Query: 940  DECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGA 999
              C   +C+GHG CV G C C   +  + C E  CP   CSGHGFC  G C C++G+ G 
Sbjct: 200  PACP-ENCSGHGECVRGVCQCHEDFMSEDCSEKRCP-GDCSGHGFCDTGECYCEEGFTGL 257

Query: 1000 DC 1001
            DC
Sbjct: 258  DC 259



 Score =  101 bits (242), Expect = 4e-20
 Identities = 49/127 (38%), Positives = 66/127 (51%), Gaps = 10/127 (7%)

Query: 947  CNGHGHCVNGKCSC--VRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTM 1004
            C+GHG      CSC    G +G  C  + CP   CSGHG C++G C+C + + GADCG  
Sbjct: 142  CSGHGTFSLETCSCHCEEGREGPACERLACPG-ACSGHGRCVDGRCLCHEPYVGADCGYP 200

Query: 1005 DKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAG 1064
                  C  +CSGHG  +     C CH  +  EDCS++ C  +C  HG C    C C  G
Sbjct: 201  -----ACPENCSGHG--ECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEG 253

Query: 1065 WSGEFCS 1071
            ++G  C+
Sbjct: 254  FTGLDCA 260



 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 39/98 (39%), Positives = 51/98 (52%), Gaps = 3/98 (3%)

Query: 878 CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
           CP  CSG G C+ G C C   + G DC    CP  CS  GE + G CQC+  +  ++CS 
Sbjct: 171 CPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCS- 229

Query: 938 RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP 975
               C   DC+GHG C  G+C C  G+ G  C ++  P
Sbjct: 230 -EKRCP-GDCSGHGFCDTGECYCEEGFTGLDCAQVVTP 265



 Score = 94.3 bits (224), Expect = 6e-18
 Identities = 50/134 (37%), Positives = 64/134 (47%), Gaps = 15/134 (11%)

Query: 913  CSQRGEYI--NGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVNGKCSCVRGYKGKFC 969
            CS  G +      C C  G +G  C    +    P  C+GHG CV+G+C C   Y G  C
Sbjct: 142  CSGHGTFSLETCSCHCEEGREGPAC----ERLACPGACSGHGRCVDGRCLCHEPYVGADC 197

Query: 970  GEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            G   CP   CSGHG C+ G C C + +   DC        +C  DCSGHG    DT  C 
Sbjct: 198  GYPACPE-NCSGHGECVRGVCQCHEDFMSEDCSEK-----RCPGDCSGHGF--CDTGECY 249

Query: 1030 CHAKWSGEDCSKEV 1043
            C   ++G DC++ V
Sbjct: 250  CEEGFTGLDCAQVV 263



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 44/134 (32%), Positives = 60/134 (44%), Gaps = 16/134 (11%)

Query: 1035 SGEDCSKEVCSLE--CGPHGRCVGESCS--CAAGWSGEFCSVRLCDARCAEHGQCKNGTC 1090
            S + C + V  L   C  HG    E+CS  C  G  G  C    C   C+ HG+C +G C
Sbjct: 127  SAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRC 186

Query: 1091 LCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRD 1150
            LC   + G  C    CP +C+GHG+C      R  C+C + +   DC+   E+ C     
Sbjct: 187  LCHEPYVGADCGYPACPENCSGHGEC-----VRGVCQCHEDFMSEDCS---EKRC----P 234

Query: 1151 NDKDGLVDCEDPEC 1164
             D  G   C+  EC
Sbjct: 235  GDCSGHGFCDTGEC 248


>Z99297-1|CAI19966.1| 1299|Homo sapiens tenascin N protein.
          Length = 1299

 Score =  108 bits (260), Expect = 3e-22
 Identities = 46/123 (37%), Positives = 59/123 (47%), Gaps = 5/123 (4%)

Query: 1015 CSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL 1074
            CSGHGTF ++T +C C     G  C +  C   C  HGRCV   C C   + G  C    
Sbjct: 142  CSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPA 201

Query: 1075 CDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
            C   C+ HG+C  G C C   +    C+ + CP  C+GHG C        EC C +G+ G
Sbjct: 202  CPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTG-----ECYCEEGFTG 256

Query: 1135 PDC 1137
             DC
Sbjct: 257  LDC 259



 Score =  106 bits (254), Expect = 1e-21
 Identities = 47/122 (38%), Positives = 63/122 (51%), Gaps = 6/122 (4%)

Query: 882  CSGKGECLMG--HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH 939
            CSG G   +    C C+ G  G  C +  CP  CS  G  ++G C C+  + G +C   +
Sbjct: 142  CSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCG--Y 199

Query: 940  DECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGA 999
              C   +C+GHG CV G C C   +  + C E  CP   CSGHGFC  G C C++G+ G 
Sbjct: 200  PACP-ENCSGHGECVRGVCQCHEDFMSEDCSEKRCP-GDCSGHGFCDTGECYCEEGFTGL 257

Query: 1000 DC 1001
            DC
Sbjct: 258  DC 259



 Score =  101 bits (242), Expect = 4e-20
 Identities = 49/127 (38%), Positives = 66/127 (51%), Gaps = 10/127 (7%)

Query: 947  CNGHGHCVNGKCSC--VRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTM 1004
            C+GHG      CSC    G +G  C  + CP   CSGHG C++G C+C + + GADCG  
Sbjct: 142  CSGHGTFSLETCSCHCEEGREGPACERLACPG-ACSGHGRCVDGRCLCHEPYVGADCGYP 200

Query: 1005 DKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAG 1064
                  C  +CSGHG  +     C CH  +  EDCS++ C  +C  HG C    C C  G
Sbjct: 201  -----ACPENCSGHG--ECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEG 253

Query: 1065 WSGEFCS 1071
            ++G  C+
Sbjct: 254  FTGLDCA 260



 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 39/98 (39%), Positives = 51/98 (52%), Gaps = 3/98 (3%)

Query: 878 CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
           CP  CSG G C+ G C C   + G DC    CP  CS  GE + G CQC+  +  ++CS 
Sbjct: 171 CPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCS- 229

Query: 938 RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP 975
               C   DC+GHG C  G+C C  G+ G  C ++  P
Sbjct: 230 -EKRCP-GDCSGHGFCDTGECYCEEGFTGLDCAQVVTP 265



 Score = 94.3 bits (224), Expect = 6e-18
 Identities = 50/134 (37%), Positives = 64/134 (47%), Gaps = 15/134 (11%)

Query: 913  CSQRGEYI--NGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVNGKCSCVRGYKGKFC 969
            CS  G +      C C  G +G  C    +    P  C+GHG CV+G+C C   Y G  C
Sbjct: 142  CSGHGTFSLETCSCHCEEGREGPAC----ERLACPGACSGHGRCVDGRCLCHEPYVGADC 197

Query: 970  GEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            G   CP   CSGHG C+ G C C + +   DC        +C  DCSGHG    DT  C 
Sbjct: 198  GYPACPE-NCSGHGECVRGVCQCHEDFMSEDCSEK-----RCPGDCSGHGF--CDTGECY 249

Query: 1030 CHAKWSGEDCSKEV 1043
            C   ++G DC++ V
Sbjct: 250  CEEGFTGLDCAQVV 263



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 44/134 (32%), Positives = 60/134 (44%), Gaps = 16/134 (11%)

Query: 1035 SGEDCSKEVCSLE--CGPHGRCVGESCS--CAAGWSGEFCSVRLCDARCAEHGQCKNGTC 1090
            S + C + V  L   C  HG    E+CS  C  G  G  C    C   C+ HG+C +G C
Sbjct: 127  SAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRC 186

Query: 1091 LCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRD 1150
            LC   + G  C    CP +C+GHG+C      R  C+C + +   DC+   E+ C     
Sbjct: 187  LCHEPYVGADCGYPACPENCSGHGEC-----VRGVCQCHEDFMSEDCS---EKRC----P 234

Query: 1151 NDKDGLVDCEDPEC 1164
             D  G   C+  EC
Sbjct: 235  GDCSGHGFCDTGEC 248


>AL049689-1|CAB41260.1| 1294|Homo sapiens hypothetical protein
            protein.
          Length = 1294

 Score =  108 bits (260), Expect = 3e-22
 Identities = 46/123 (37%), Positives = 59/123 (47%), Gaps = 5/123 (4%)

Query: 1015 CSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL 1074
            CSGHGTF ++T +C C     G  C +  C   C  HGRCV   C C   + G  C    
Sbjct: 137  CSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPA 196

Query: 1075 CDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
            C   C+ HG+C  G C C   +    C+ + CP  C+GHG C        EC C +G+ G
Sbjct: 197  CPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTG-----ECYCEEGFTG 251

Query: 1135 PDC 1137
             DC
Sbjct: 252  LDC 254



 Score =  106 bits (254), Expect = 1e-21
 Identities = 47/122 (38%), Positives = 63/122 (51%), Gaps = 6/122 (4%)

Query: 882  CSGKGECLMG--HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH 939
            CSG G   +    C C+ G  G  C +  CP  CS  G  ++G C C+  + G +C   +
Sbjct: 137  CSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCG--Y 194

Query: 940  DECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGA 999
              C   +C+GHG CV G C C   +  + C E  CP   CSGHGFC  G C C++G+ G 
Sbjct: 195  PACP-ENCSGHGECVRGVCQCHEDFMSEDCSEKRCP-GDCSGHGFCDTGECYCEEGFTGL 252

Query: 1000 DC 1001
            DC
Sbjct: 253  DC 254



 Score =  101 bits (242), Expect = 4e-20
 Identities = 49/127 (38%), Positives = 66/127 (51%), Gaps = 10/127 (7%)

Query: 947  CNGHGHCVNGKCSC--VRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTM 1004
            C+GHG      CSC    G +G  C  + CP   CSGHG C++G C+C + + GADCG  
Sbjct: 137  CSGHGTFSLETCSCHCEEGREGPACERLACPG-ACSGHGRCVDGRCLCHEPYVGADCGYP 195

Query: 1005 DKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAG 1064
                  C  +CSGHG  +     C CH  +  EDCS++ C  +C  HG C    C C  G
Sbjct: 196  -----ACPENCSGHG--ECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEG 248

Query: 1065 WSGEFCS 1071
            ++G  C+
Sbjct: 249  FTGLDCA 255



 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 39/98 (39%), Positives = 51/98 (52%), Gaps = 3/98 (3%)

Query: 878 CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
           CP  CSG G C+ G C C   + G DC    CP  CS  GE + G CQC+  +  ++CS 
Sbjct: 166 CPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCS- 224

Query: 938 RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP 975
               C   DC+GHG C  G+C C  G+ G  C ++  P
Sbjct: 225 -EKRCP-GDCSGHGFCDTGECYCEEGFTGLDCAQVVTP 260



 Score = 94.3 bits (224), Expect = 6e-18
 Identities = 50/134 (37%), Positives = 64/134 (47%), Gaps = 15/134 (11%)

Query: 913  CSQRGEYI--NGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVNGKCSCVRGYKGKFC 969
            CS  G +      C C  G +G  C    +    P  C+GHG CV+G+C C   Y G  C
Sbjct: 137  CSGHGTFSLETCSCHCEEGREGPAC----ERLACPGACSGHGRCVDGRCLCHEPYVGADC 192

Query: 970  GEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            G   CP   CSGHG C+ G C C + +   DC        +C  DCSGHG    DT  C 
Sbjct: 193  GYPACPE-NCSGHGECVRGVCQCHEDFMSEDCSEK-----RCPGDCSGHGF--CDTGECY 244

Query: 1030 CHAKWSGEDCSKEV 1043
            C   ++G DC++ V
Sbjct: 245  CEEGFTGLDCAQVV 258



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 44/134 (32%), Positives = 60/134 (44%), Gaps = 16/134 (11%)

Query: 1035 SGEDCSKEVCSLE--CGPHGRCVGESCS--CAAGWSGEFCSVRLCDARCAEHGQCKNGTC 1090
            S + C + V  L   C  HG    E+CS  C  G  G  C    C   C+ HG+C +G C
Sbjct: 122  SAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRC 181

Query: 1091 LCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRD 1150
            LC   + G  C    CP +C+GHG+C      R  C+C + +   DC+   E+ C     
Sbjct: 182  LCHEPYVGADCGYPACPENCSGHGEC-----VRGVCQCHEDFMSEDCS---EKRC----P 229

Query: 1151 NDKDGLVDCEDPEC 1164
             D  G   C+  EC
Sbjct: 230  GDCSGHGFCDTGEC 243


>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
            protein.
          Length = 1640

 Score =  107 bits (258), Expect = 5e-22
 Identities = 101/336 (30%), Positives = 128/336 (38%), Gaps = 83/336 (24%)

Query: 878  CPNGCSGKGECLMGHC--QCQPGFGGDDCSKSVCPV---------LCSQRG---EYINGE 923
            CP G +   + + G C  +C  GF G+DC +  CPV          CS  G     + G+
Sbjct: 776  CPVGVAC--DSVSGECGKRCPAGFQGEDCGQE-CPVGTFGVNCSSSCSCGGAPCHGVTGQ 832

Query: 924  CQCNPGWKGKECSLRHDE------CE--VPDCNGHGHC--VNGKCSCVRGYKGKFCGEID 973
            C+C PG  G++C     E      C+   P C     C    G C C+ G+ G  C ++ 
Sbjct: 833  CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV- 891

Query: 974  CPH----PTCS--------GHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCS----- 1016
            CP     P+C         GH     G C C  GW G  C     D     PDCS     
Sbjct: 892  CPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRAC-DTGHWGPDCSHPCNC 950

Query: 1017 --GHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP---------HGRC---VGESCSCA 1062
              GHG+ D  +  C C A + G  C ++      GP         HG     V  +C+C 
Sbjct: 951  SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCP 1010

Query: 1063 AGWSGEFCSVRLCDA-----------RCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPRS 1109
            AGW G FC    C A            C     C   NG+CLC +G  G  C  E CP  
Sbjct: 1011 AGWRGTFCE-HACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA-ETCPAH 1068

Query: 1110 CAGHG---QCRVDNDG-----RWECKCFDGWDGPDC 1137
              GH     C   N         +C C  GW GP C
Sbjct: 1069 TYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSC 1104



 Score = 89.8 bits (213), Expect = 1e-16
 Identities = 108/377 (28%), Positives = 136/377 (36%), Gaps = 96/377 (25%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP-----------VLCSQRG--EYINGE 923
            +C NG  G  + + G C+C PG  G +C    CP             C+ RG    + G 
Sbjct: 644  SCQNG--GTCDSVTGACRCPPGVSGTNCEDG-CPKGYYGKHCRKKCNCANRGRCHRLYGA 700

Query: 924  CQCNPGWKGKECSLRHDECEV-PDCNGHGHCV----------NGKCSCVRGYKGKFCG-- 970
            C C+PG  G+ C L        P C+    CV          +G CSC  G++G+ C   
Sbjct: 701  CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAE 760

Query: 971  -EIDCPHPTCSGHGFC--------IEGTC--VCKKGWKGADCG---TMDKDALQCLPDCS 1016
             E+    P C     C        + G C   C  G++G DCG    +    + C   CS
Sbjct: 761  CELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS 820

Query: 1017 -GHGTFDVDTQTCSCHAKWSGEDCS------------KEVC-----SLECGPH-GRC--- 1054
             G       T  C C    +GEDC             +E+C     +  C P  G C   
Sbjct: 821  CGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCL 880

Query: 1055 ---VGESCS--CAAGWSGEFCSVRLCDARCAEHGQC--KNGTCLCVSGWNGRHCTL---- 1103
               VG  C   C AGW G  C  R C   CA  G C    G C C  GW G  C      
Sbjct: 881  PGFVGSRCQDVCPAGWYGPSCQTR-CS--CANDGHCHPATGHCSCAPGWTGFSCQRACDT 937

Query: 1104 ----EGCPRSC---AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDK-DG 1155
                  C   C   AGHG C   +     C C  G+ GP C    EQ C         + 
Sbjct: 938  GHWGPDCSHPCNCSAGHGSCDAISG---LCLCEAGYVGPRC----EQQCPQGHFGPGCEQ 990

Query: 1156 LVDCEDPECCQ--SPAC 1170
            L  C+    C   S AC
Sbjct: 991  LCQCQHGAACDHVSGAC 1007



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 99/345 (28%), Positives = 120/345 (34%), Gaps = 83/345 (24%)

Query: 869  LVAEEMTHNCPNGCSGKGEC--LMGHCQCQPGFGGDDCSKSVCP----VLCSQRGEYING 922
            L  +   H+C   C   G C  + GHC C  G+ G  C K   P      C   G  +NG
Sbjct: 1112 LYGDNCRHSCL--CQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNG 1169

Query: 923  --------ECQCNPGWKGKECS---LRH-------DECEVPDCNGHGHCVNGKCSCVRGY 964
                     C C  GW G +C    LR          C  P      H V G C C  G+
Sbjct: 1170 GLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHH-VTGACRCPPGF 1228

Query: 965  KGKFCGEI--------DCPHPT-CSGHG-FC--IEGTCVCKKGWKGADC------GTMDK 1006
             G  C +         DC     C G    C    GTC C  G+ G  C      G    
Sbjct: 1229 TGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGP 1288

Query: 1007 DALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS------------KEVCSLECGPHGRC 1054
               Q L  C   G+ D  T  C C   + G DC+              VC   CG    C
Sbjct: 1289 GCEQ-LCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCG--CGQGAAC 1345

Query: 1055 --VGESCSCAAGWSGEFCSVRL--------CDARCA--EHGQC--KNGTCLCVSGWNGRH 1100
              V  +C C  G +G  C            C+  C+    G C   NG+C C  GW GRH
Sbjct: 1346 DPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRH 1405

Query: 1101 CTLEGCP---RSCAGHGQCRVDNDGRWE-----CKCFDGWDGPDC 1137
            C L  CP      A H +C   N+   E     C+C  G+ G  C
Sbjct: 1406 CEL-ACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQAC 1449



 Score = 87.0 bits (206), Expect = 9e-16
 Identities = 85/300 (28%), Positives = 109/300 (36%), Gaps = 66/300 (22%)

Query: 891  GHCQCQPGFGGDDCSKSV--------CPVLCSQRGEY-----INGECQCNPGWKGKECSL 937
            G C+C PGF G  C ++         C  +C   GE        G C C  G+ G  C  
Sbjct: 1220 GACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQ 1279

Query: 938  RHDE------CE-VPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPH----PTCS---- 980
            R         CE +  C   G C    G C C  G+ G  C  + CP     P C+    
Sbjct: 1280 RCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCN-LTCPQGRFGPNCTHVCG 1338

Query: 981  -GHGFC---IEGTCVCKKGWKGADCGT---MDKDALQCLPDCS--GHGTFDVDTQTCSCH 1031
             G G     + GTC+C  G  G  C      ++  + C   CS    G       +CSC 
Sbjct: 1339 CGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCG 1398

Query: 1032 AKWSGEDCSKE--------VCSLECGPHGRCVGE----SCSCAAGWSGEFCSVRL----- 1074
              W+G  C            C LEC  H     E    +C C  G+ G+ C         
Sbjct: 1399 LGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFH 1458

Query: 1075 ---CDARC-AEHGQ-CK--NGTCLCVSGWNGRHCTLEGCPRSCAGHG-QCRVDNDGRWEC 1126
               C   C  +HG  C   +G CLC +G++G  C   GC     G G   R D DG   C
Sbjct: 1459 GAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCE-RGCEPGSFGEGCHQRCDCDGGAPC 1517



 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 93/318 (29%), Positives = 118/318 (37%), Gaps = 65/318 (20%)

Query: 883  SGKGECLMGH----CQ--CQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            +G   C  G+    CQ  C PG  G  C + +C  L     +   G C+C  G+ G +C+
Sbjct: 1263 TGTCSCAAGYHGPSCQQRCPPGRYGPGCEQ-LCGCLNGGSCDAATGACRCPTGFLGTDCN 1321

Query: 937  LRHDECEV-PDCN-----GHGHC---VNGKCSCVRGYKGKFCGE--------IDCPHP-T 978
            L   +    P+C      G G     V G C C  G  G  C          + C H  +
Sbjct: 1322 LTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCS 1381

Query: 979  CSGHGFC--IEGTCVCKKGWKGADCGTM---DKDALQCLPDCSGHG--TFDVDTQTCSCH 1031
            C   G C    G+C C  GW G  C       +    C  +CS H   T +  T TC C 
Sbjct: 1382 CRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCG 1441

Query: 1032 AKWSGEDCSKEV--------CSLECG-PHGR-C--VGESCSCAAGWSGEFCSVRL----- 1074
              + G+ C            C   C   HG  C  +   C C AG+ G FC         
Sbjct: 1442 PGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSF 1501

Query: 1075 ---CDARCAEHG--QCK--NGTCLCVSGWNGRHCTLEGCPR-----SCAGHGQCR--VDN 1120
               C  RC   G   C    G CLC  G +G  C L+ C R     SC  H  C    D 
Sbjct: 1502 GEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLD-CRRGQFGPSCTLHCDCGGGADC 1560

Query: 1121 DG-RWECKCFDGWDGPDC 1137
            D    +C C DG+ GP C
Sbjct: 1561 DPVSGQCHCVDGYMGPTC 1578



 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 88/306 (28%), Positives = 115/306 (37%), Gaps = 57/306 (18%)

Query: 901  GDDCSKSVCPVLCSQRGEYING--ECQCNPGWKGKECS------LRHDECEVP-DCNGHG 951
            G DCS + C   C   G  + G   C C  GW G  C+           C     C   G
Sbjct: 592  GHDCSLT-CDD-CRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGG 649

Query: 952  HC--VNGKCSCVRGYKGKFCGEIDCPHP----------TCSGHGFC--IEGTCVCKKGWK 997
             C  V G C C  G  G  C E  CP             C+  G C  + G C+C  G  
Sbjct: 650  TCDSVTGACRCPPGVSGTNC-EDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLY 708

Query: 998  GADCG-TMDKDAL--QCLPDC---SGH-GTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP 1050
            G  C  T    A    C  +C     H  + D    +CSC A + GE C  E C  E G 
Sbjct: 709  GRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAE-C--ELGY 765

Query: 1051 HGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSC 1110
             G    ++C+C  G + +  S   C  RC    Q ++    C  G  G +C+   C  SC
Sbjct: 766  FGPGCWQACTCPVGVACDSVSGE-CGKRCPAGFQGEDCGQECPVGTFGVNCS-SSC--SC 821

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
             G   C   +    +C+C  G  G DC    E  C + R       + C+  E C  PAC
Sbjct: 822  GG-APC---HGVTGQCRCPPGRTGEDC----EADCPEGRWG-----LGCQ--EIC--PAC 864

Query: 1171 KSSQLC 1176
            + +  C
Sbjct: 865  QHAARC 870



 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 36/103 (34%), Positives = 46/103 (44%), Gaps = 14/103 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP G  G   C  G   C+PG  G+ C +  C        + + G C C PG  G  C+L
Sbjct: 1483 CPAGFHGHF-CERG---CEPGSFGEGCHQR-CDCDGGAPCDPVTGLCLCPPGRSGATCNL 1537

Query: 938  --RHDE----CEVP-DCNGHGHC--VNGKCSCVRGYKGKFCGE 971
              R  +    C +  DC G   C  V+G+C CV GY G  C E
Sbjct: 1538 DCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCRE 1580



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 55/182 (30%), Positives = 63/182 (34%), Gaps = 44/182 (24%)

Query: 991  VCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSG----EDCSKEV--- 1043
            VC     G DC      +L C  DC   GT  +    C C   W+G    E C  +    
Sbjct: 585  VCLDDSFGHDC------SLTC-DDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGK 637

Query: 1044 -CSLECGPH--GRC--VGESCSCAAGWSGEFCS--------VRLC--DARCAEHGQCKN- 1087
             CS  C     G C  V  +C C  G SG  C          + C     CA  G+C   
Sbjct: 638  NCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL 697

Query: 1088 -GTCLCVSGWNGRHCTL--------EGCPRSC---AGHGQCRVDNDGRWECKCFDGWDGP 1135
             G CLC  G  GR C L         GC   C     H Q     DG   C C  G+ G 
Sbjct: 698  YGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDG--SCSCKAGFRGE 755

Query: 1136 DC 1137
             C
Sbjct: 756  RC 757



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 79/319 (24%), Positives = 116/319 (36%), Gaps = 65/319 (20%)

Query: 888  CLMGHCQCQPGFGGDDCSKSVCPV-LCSQRGEYINGE---CQCNPGWKGKECSLRHDECE 943
            C  G  Q QP   G  C  + C   LC   G  + G    C C PG++G  C    DEC 
Sbjct: 185  CCRGWMQ-QPDEEG--CLSAECSAGLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECR 241

Query: 944  VPDCNGHGHCVNGK----CSCVRGYK----GKFCGEID-CPHPTCSGHGFCIEGT----- 989
              +      CVN      C C  G++     + C  I+ C          C++ T     
Sbjct: 242  THNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHR 301

Query: 990  CVCKKGWKGADCGTMDKDALQCL---PDCSGHGTFDVDTQTCSCHAKW----SGEDCSK- 1041
            C C+ G++  + G        C      C            C CH  +     G+ C   
Sbjct: 302  CQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDV 361

Query: 1042 EVCS---LECGPHGRCVGE----SCSCAAGW----SGEFC---SVRLCDARCAEHGQCKN 1087
            + C+    +C  HG C+       C C AG+     G  C    + + ++  A +G C +
Sbjct: 362  DECAAGLAQCA-HG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH 419

Query: 1088 G--------TCLCVSGW----NGRHC-TLEGCPRSCAGHGQCRVDNDGRWECKCFDGW-- 1132
            G         C C  G+    + R C  ++ C  S      C  +N G +EC C+ G+  
Sbjct: 420  GCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVC-TNNPGGYECGCYAGYRL 478

Query: 1133 --DGPDCTTLKEQICDDSR 1149
              DG  C  + E  C  SR
Sbjct: 479  SADGCGCEDVDE--CASSR 495


>BC106950-1|AAI06951.1|  685|Homo sapiens delta-like 4 (Drosophila)
            protein.
          Length = 685

 Score =  105 bits (251), Expect = 3e-21
 Identities = 89/313 (28%), Positives = 128/313 (40%), Gaps = 43/313 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + GD+CS+ +C       G Y+   +G   C PGW G+ C  +   C       +G
Sbjct: 175  CSDNYYGDNCSR-LCKKRNDHFGHYVCQPDGNLSCLPGWTGEYC--QQPICLSGCHEQNG 231

Query: 952  HCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFC-IEGTCVCKKGWKGADCGTMDKDAL 1009
            +C    +C C  G++G+ C E   PH  C  HG C     C C +GW G  C   D+D  
Sbjct: 232  YCSKPAECLCRPGWQGRLCNEC-IPHNGCR-HGTCSTPWQCTCDEGWGGLFC---DQDLN 286

Query: 1010 QCL--PDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSLECGP---HGRCV----GE 1057
             C     C    T     Q   TC+C   ++G DC  E+   +  P    G C     G 
Sbjct: 287  YCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGY 346

Query: 1058 SCSCAAGWSGEFC---SVRLCDARCAEHGQCK------NGTCLCVSGWNGRHC--TLEGC 1106
             C C  G+ G  C   ++   D+ C   G C+      N  C C   + G +C   ++ C
Sbjct: 347  HCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRC 406

Query: 1107 PRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG--LVDCEDPE 1163
              + CA  GQC      R  C+C  G+ G  C   +  + D +R+    G    D E+  
Sbjct: 407  TSNPCANGGQCLNRGPSRM-CRCRPGFTGTYC---ELHVSDCARNPCAHGGTCHDLENGL 462

Query: 1164 CCQSPACKSSQLC 1176
             C  PA  S + C
Sbjct: 463  MCTCPAGFSGRRC 475



 Score =  103 bits (248), Expect = 7e-21
 Identities = 77/277 (27%), Positives = 113/277 (40%), Gaps = 35/277 (12%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCSQRGEYIN--GECQCNPGWKGKECSLRHDECEVPDCN 948
            G+  C PG+ G+ C + +C   C ++  Y +   EC C PGW+G+ C    +EC   +  
Sbjct: 204  GNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLC----NECIPHNGC 259

Query: 949  GHGHC-VNGKCSCVRGYKGKFCGE--IDCPHPT-CSGHGFCIEG-----TCVCKKGWKGA 999
             HG C    +C+C  G+ G FC +    C H + C     C        TC C+ G+ G 
Sbjct: 260  RHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGV 319

Query: 1000 DCGTMDKDALQCLPDCSGHGTFD-VDTQTCSC-------HAKWSGEDCSKEVC--SLECG 1049
            DC  ++       P  +G    D  D   C C       H + S   C+   C     C 
Sbjct: 320  DC-ELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCR 378

Query: 1050 PHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCKN----GTCLCVSGWNGRHCT 1102
               +    +C C   ++G  C  ++  C +  CA  GQC N      C C  G+ G +C 
Sbjct: 379  ERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCE 438

Query: 1103 L--EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L    C R+   HG    D +    C C  G+ G  C
Sbjct: 439  LHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRC 475



 Score = 84.2 bits (199), Expect = 6e-15
 Identities = 82/287 (28%), Positives = 118/287 (41%), Gaps = 55/287 (19%)

Query: 880  NGCSGKGECLMG-HCQCQPGFGGDDCSK--------SVCP--VLCSQRGEYINGECQCNP 928
            NGC   G C     C C  G+GG  C +        S C     CS  G+  +  C C P
Sbjct: 257  NGCR-HGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQR-SYTCTCRP 314

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEIDCPHPTCS-GHG 983
            G+ G +C L   EC+   C   G C + +    C C  GY G     + C H T S    
Sbjct: 315  GYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYG-----LHCEHSTLSCADS 369

Query: 984  FCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV 1043
             C  G   C++  +GA+       A +C P+ +G    +     C+ +   +G  C    
Sbjct: 370  PCFNGGS-CRERNQGANY------ACECPPNFTG-SNCEKKVDRCTSNPCANGGQC---- 417

Query: 1044 CSLECGPHGRCVGESCSCAAGWSGEFCSVRLCD-AR--CAEHGQC---KNG-TCLCVSGW 1096
              L  GP        C C  G++G +C + + D AR  CA  G C   +NG  C C +G+
Sbjct: 418  --LNRGP-----SRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGF 470

Query: 1097 NGRHC----TLEGCPRS-CAGHGQCRVD-NDGRWECKCFDGWDGPDC 1137
            +GR C    +++ C  S C     C  D +   + C C  G+ G  C
Sbjct: 471  SGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 56/186 (30%), Positives = 71/186 (38%), Gaps = 25/186 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C---PVL----CSQRGEYINGECQCNP 928
            C NG S K +    HC C PG+ G  C  S   C   P      C +R +  N  C+C P
Sbjct: 333  CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPP 392

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFC--GEIDCPHPTCSGH 982
             + G  C  + D C    C   G C+N      C C  G+ G +C     DC    C+  
Sbjct: 393  NFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHG 452

Query: 983  GFC--IEG--TCVCKKGWKGADCGTMDK-DALQCLPDCSGHGT----FDVDTQTCSCHAK 1033
            G C  +E    C C  G+ G  C      DA    P C    T       DT  C+C   
Sbjct: 453  GTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP-CFNRATCYTDLSTDTFVCNCPYG 511

Query: 1034 WSGEDC 1039
            + G  C
Sbjct: 512  FVGSRC 517


>BC035009-1|AAH35009.1|  737|Homo sapiens delta/notch-like EGF repeat
            containing protein.
          Length = 737

 Score =  105 bits (251), Expect = 3e-21
 Identities = 86/301 (28%), Positives = 117/301 (38%), Gaps = 48/301 (15%)

Query: 882  CSGKGECLMG------HCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGE---C 924
            CSGKG+C          C C+  + G      D C +  C     C    E  +G    C
Sbjct: 319  CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTC 378

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CPHPT 978
             C PG+ G+ C  + D C +  C     C++      C C  GY G  C E +D C    
Sbjct: 379  VCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDLCASSP 438

Query: 979  CSGHGFC-IEG---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF-DVDTQ-TCSCHA 1032
            C  +G C ++G   TC C  G+ G  C  +       L  C+ HGT   V T   C C  
Sbjct: 439  CQNNGTCYVDGVHFTCNCSPGFTGPTCAQLID--FCALSPCA-HGTCRSVGTSYKCLCDP 495

Query: 1033 KWSGEDCSKEV--C-SLECGPHGRC----VGESCSCAAGWSGEFCSV---RLCDARCAEH 1082
             + G  C +E   C S  C     C     G  C C A + G  C +      +  C   
Sbjct: 496  GYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNG 555

Query: 1083 GQCK----NGTCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPD 1136
              C     NGTC+C  G+ G  C ++   C  +   HG   +D    + C C  GW G +
Sbjct: 556  ATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGAN 615

Query: 1137 C 1137
            C
Sbjct: 616  C 616



 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 69/223 (30%), Positives = 94/223 (42%), Gaps = 29/223 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGE-YING---ECQCNPGW 930
            C NG +         CQC  G+ G  C + V  C    C   G  Y++G    C C+PG+
Sbjct: 401  CRNGATCISSLSGFTCQCPEGYFGSACEEKVDLCASSPCQNNGTCYVDGVHFTCNCSPGF 460

Query: 931  KGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGF 984
             G  C+   D C +  C  HG C     + KC C  GY G +C E   +C    C     
Sbjct: 461  TGPTCAQLIDFCALSPC-AHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAAT 519

Query: 985  C---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD--TQTCSCHAKWSGED 1038
            C   + G  CVC   +KG  C  + KD    +  C    T D D    TC C   ++GE+
Sbjct: 520  CRDLVNGYECVCLAEYKGTHC-ELYKDPCANV-SCLNGATCDSDGLNGTCICAPGFTGEE 577

Query: 1039 CSKEVCSLECGP--HG-RCV----GESCSCAAGWSGEFCSVRL 1074
            C  ++   +  P  HG  C+    G +C C  GW G  C + L
Sbjct: 578  CDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHL 620



 Score = 89.8 bits (213), Expect = 1e-16
 Identities = 74/245 (30%), Positives = 110/245 (44%), Gaps = 38/245 (15%)

Query: 893  CQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKECSLRHDECEVP 945
            C C PG+ G+ C   +  C +   + G      ++G  CQC  G+ G  C  + D C   
Sbjct: 378  CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDLCASS 437

Query: 946  DCNGHGHC----VNGKCSCVRGYKGKFCGE-ID-CPHPTCSGHGFCIE-GT---CVCKKG 995
             C  +G C    V+  C+C  G+ G  C + ID C    C+ HG C   GT   C+C  G
Sbjct: 438  PCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCA-HGTCRSVGTSYKCLCDPG 496

Query: 996  WKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS--KEVCS-LECG 1049
            + G  C   +++  +CL   C    T    V+   C C A++ G  C   K+ C+ + C 
Sbjct: 497  YHGLYC---EEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCL 553

Query: 1050 PHGRCVGE----SCSCAAGWSGEFCSVRL--CDARCAEHG-QC---KNG-TCLCVSGWNG 1098
                C  +    +C CA G++GE C + +  CD+    HG  C    NG  C C  GW G
Sbjct: 554  NGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVG 613

Query: 1099 RHCTL 1103
             +C +
Sbjct: 614  ANCEI 618



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 26/152 (17%)

Query: 1014 DCSGHGTFDVD----TQTCSCHAKWSGEDCSK-EVCSLE-CGPHGRCVGES--------- 1058
            +CSG G         T +C+C  ++ G  C + + C  + C  +  C+  +         
Sbjct: 318  ECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFT 377

Query: 1059 CSCAAGWSGEFCSVRL--CDAR-CAEHGQCKNG----TCLCVSGWNGRHCT--LEGCPRS 1109
            C C  G++GE C  ++  C    C     C +     TC C  G+ G  C   ++ C  S
Sbjct: 378  CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDLCASS 437

Query: 1110 -CAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
             C  +G C VD    + C C  G+ GP C  L
Sbjct: 438  PCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQL 468



 Score = 41.5 bits (93), Expect = 0.045
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 7/68 (10%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPV-LCSQRGEYI---NG-ECQCNPG 929
           +C NG +   + L G C C PGF G++C   +  C    C   G  +   NG  C C  G
Sbjct: 551 SCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHG 610

Query: 930 WKGKECSL 937
           W G  C +
Sbjct: 611 WVGANCEI 618



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 5/54 (9%)

Query: 1089 TCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDGRWE---CKCFDGWDGPDC 1137
            +C C +G +G +C L  + C  +   HG C   +    +   C C +G++GP+C
Sbjct: 79   SCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 12/89 (13%)

Query: 891 GHCQCQPGFGGDDCSK--SVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCN 948
           G C  QP   G  C+      P   +  GE     C C  G  G  C L  D C    C+
Sbjct: 46  GPCAAQPCRNGGVCTSRPEPDPQHPAPAGEP-GYSCTCPAGISGANCQLVADPCASNPCH 104

Query: 949 GHGHCVNGK--------CSCVRGYKGKFC 969
            HG+C +          C C  GY+G  C
Sbjct: 105 -HGNCSSSSSSSSDGYLCICNEGYEGPNC 132



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 10/56 (17%)

Query: 1056 GESCSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT--------CLCVSGWNGRHC 1101
            G SC+C AG SG  C +    C +    HG C + +        C+C  G+ G +C
Sbjct: 77   GYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132


>BC024766-1|AAH24766.2|  454|Homo sapiens DNER protein protein.
          Length = 454

 Score =  105 bits (251), Expect = 3e-21
 Identities = 86/301 (28%), Positives = 117/301 (38%), Gaps = 48/301 (15%)

Query: 882  CSGKGECLMG------HCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGE---C 924
            CSGKG+C          C C+  + G      D C +  C     C    E  +G    C
Sbjct: 36   CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTC 95

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CPHPT 978
             C PG+ G+ C  + D C +  C     C++      C C  GY G  C E +D C    
Sbjct: 96   VCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSP 155

Query: 979  CSGHGFC-IEG---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF-DVDTQ-TCSCHA 1032
            C  +G C ++G   TC C  G+ G  C  +       L  C+ HGT   V T   C C  
Sbjct: 156  CQNNGTCYVDGVHFTCNCSPGFTGPTCAQLID--FCALSPCA-HGTCRSVGTSYKCLCDP 212

Query: 1033 KWSGEDCSKEV--C-SLECGPHGRC----VGESCSCAAGWSGEFCSV---RLCDARCAEH 1082
             + G  C +E   C S  C     C     G  C C A + G  C +      +  C   
Sbjct: 213  GYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNG 272

Query: 1083 GQCK----NGTCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPD 1136
              C     NGTC+C  G+ G  C ++   C  +   HG   +D    + C C  GW G +
Sbjct: 273  ATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGAN 332

Query: 1137 C 1137
            C
Sbjct: 333  C 333



 Score = 93.1 bits (221), Expect = 1e-17
 Identities = 69/223 (30%), Positives = 94/223 (42%), Gaps = 29/223 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGE-YING---ECQCNPGW 930
            C NG +         CQC  G+ G  C + V P     C   G  Y++G    C C+PG+
Sbjct: 118  CRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGF 177

Query: 931  KGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGF 984
             G  C+   D C +  C  HG C     + KC C  GY G +C E   +C    C     
Sbjct: 178  TGPTCAQLIDFCALSPC-AHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAAT 236

Query: 985  C---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD--TQTCSCHAKWSGED 1038
            C   + G  CVC   +KG  C  + KD    +  C    T D D    TC C   ++GE+
Sbjct: 237  CRDLVNGYECVCLAEYKGTHC-ELYKDPCANV-SCLNGATCDSDGLNGTCICAPGFTGEE 294

Query: 1039 CSKEVCSLECGP--HG-RCV----GESCSCAAGWSGEFCSVRL 1074
            C  ++   +  P  HG  C+    G +C C  GW G  C + L
Sbjct: 295  CDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHL 337



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 74/245 (30%), Positives = 110/245 (44%), Gaps = 38/245 (15%)

Query: 893  CQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKECSLRHDECEVP 945
            C C PG+ G+ C   +  C +   + G      ++G  CQC  G+ G  C  + D C   
Sbjct: 95   CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 154

Query: 946  DCNGHGHC----VNGKCSCVRGYKGKFCGE-ID-CPHPTCSGHGFCIE-GT---CVCKKG 995
             C  +G C    V+  C+C  G+ G  C + ID C    C+ HG C   GT   C+C  G
Sbjct: 155  PCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCA-HGTCRSVGTSYKCLCDPG 213

Query: 996  WKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS--KEVCS-LECG 1049
            + G  C   +++  +CL   C    T    V+   C C A++ G  C   K+ C+ + C 
Sbjct: 214  YHGLYC---EEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCL 270

Query: 1050 PHGRCVGE----SCSCAAGWSGEFCSVRL--CDARCAEHG-QC---KNG-TCLCVSGWNG 1098
                C  +    +C CA G++GE C + +  CD+    HG  C    NG  C C  GW G
Sbjct: 271  NGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVG 330

Query: 1099 RHCTL 1103
             +C +
Sbjct: 331  ANCEI 335



 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 26/152 (17%)

Query: 1014 DCSGHGTFDVD----TQTCSCHAKWSGEDCSK-EVCSLE-CGPHGRCVGES--------- 1058
            +CSG G         T +C+C  ++ G  C + + C  + C  +  C+  +         
Sbjct: 35   ECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFT 94

Query: 1059 CSCAAGWSGEFCSVRL--CDAR-CAEHGQCKNG----TCLCVSGWNGRHCT--LEGCPRS 1109
            C C  G++GE C  ++  C    C     C +     TC C  G+ G  C   ++ C  S
Sbjct: 95   CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 154

Query: 1110 -CAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
             C  +G C VD    + C C  G+ GP C  L
Sbjct: 155  PCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQL 185



 Score = 41.5 bits (93), Expect = 0.045
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 7/68 (10%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPV-LCSQRGEYI---NG-ECQCNPG 929
           +C NG +   + L G C C PGF G++C   +  C    C   G  +   NG  C C  G
Sbjct: 268 SCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHG 327

Query: 930 WKGKECSL 937
           W G  C +
Sbjct: 328 WVGANCEI 335


>AY358894-1|AAQ89253.1|  685|Homo sapiens DLL4 protein.
          Length = 685

 Score =  105 bits (251), Expect = 3e-21
 Identities = 89/313 (28%), Positives = 128/313 (40%), Gaps = 43/313 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + GD+CS+ +C       G Y+   +G   C PGW G+ C  +   C       +G
Sbjct: 175  CSDNYYGDNCSR-LCKKRNDHFGHYVCQPDGNLSCLPGWTGEYC--QQPICLSGCHEQNG 231

Query: 952  HCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFC-IEGTCVCKKGWKGADCGTMDKDAL 1009
            +C    +C C  G++G+ C E   PH  C  HG C     C C +GW G  C   D+D  
Sbjct: 232  YCSKPAECLCRPGWQGRLCNEC-IPHNGCR-HGTCSTPWQCTCDEGWGGLFC---DQDLN 286

Query: 1010 QCL--PDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSLECGP---HGRCV----GE 1057
             C     C    T     Q   TC+C   ++G DC  E+   +  P    G C     G 
Sbjct: 287  YCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGY 346

Query: 1058 SCSCAAGWSGEFC---SVRLCDARCAEHGQCK------NGTCLCVSGWNGRHC--TLEGC 1106
             C C  G+ G  C   ++   D+ C   G C+      N  C C   + G +C   ++ C
Sbjct: 347  HCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRC 406

Query: 1107 PRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG--LVDCEDPE 1163
              + CA  GQC      R  C+C  G+ G  C   +  + D +R+    G    D E+  
Sbjct: 407  TSNPCANGGQCLNRGPSRM-CRCRPGFTGTYC---ELHVSDCARNPCAHGGTCHDLENGL 462

Query: 1164 CCQSPACKSSQLC 1176
             C  PA  S + C
Sbjct: 463  MCTCPAGFSGRRC 475



 Score =  103 bits (248), Expect = 7e-21
 Identities = 77/277 (27%), Positives = 113/277 (40%), Gaps = 35/277 (12%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCSQRGEYIN--GECQCNPGWKGKECSLRHDECEVPDCN 948
            G+  C PG+ G+ C + +C   C ++  Y +   EC C PGW+G+ C    +EC   +  
Sbjct: 204  GNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLC----NECIPHNGC 259

Query: 949  GHGHC-VNGKCSCVRGYKGKFCGE--IDCPHPT-CSGHGFCIEG-----TCVCKKGWKGA 999
             HG C    +C+C  G+ G FC +    C H + C     C        TC C+ G+ G 
Sbjct: 260  RHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGV 319

Query: 1000 DCGTMDKDALQCLPDCSGHGTFD-VDTQTCSC-------HAKWSGEDCSKEVC--SLECG 1049
            DC  ++       P  +G    D  D   C C       H + S   C+   C     C 
Sbjct: 320  DC-ELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCR 378

Query: 1050 PHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCKN----GTCLCVSGWNGRHCT 1102
               +    +C C   ++G  C  ++  C +  CA  GQC N      C C  G+ G +C 
Sbjct: 379  ERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCE 438

Query: 1103 L--EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L    C R+   HG    D +    C C  G+ G  C
Sbjct: 439  LHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRC 475



 Score = 84.2 bits (199), Expect = 6e-15
 Identities = 82/287 (28%), Positives = 118/287 (41%), Gaps = 55/287 (19%)

Query: 880  NGCSGKGECLMG-HCQCQPGFGGDDCSK--------SVCP--VLCSQRGEYINGECQCNP 928
            NGC   G C     C C  G+GG  C +        S C     CS  G+  +  C C P
Sbjct: 257  NGCR-HGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQR-SYTCTCRP 314

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEIDCPHPTCS-GHG 983
            G+ G +C L   EC+   C   G C + +    C C  GY G     + C H T S    
Sbjct: 315  GYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYG-----LHCEHSTLSCADS 369

Query: 984  FCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV 1043
             C  G   C++  +GA+       A +C P+ +G    +     C+ +   +G  C    
Sbjct: 370  PCFNGGS-CRERNQGANY------ACECPPNFTG-SNCEKKVDRCTSNPCANGGQC---- 417

Query: 1044 CSLECGPHGRCVGESCSCAAGWSGEFCSVRLCD-AR--CAEHGQC---KNG-TCLCVSGW 1096
              L  GP        C C  G++G +C + + D AR  CA  G C   +NG  C C +G+
Sbjct: 418  --LNRGP-----SRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGF 470

Query: 1097 NGRHC----TLEGCPRS-CAGHGQCRVD-NDGRWECKCFDGWDGPDC 1137
            +GR C    +++ C  S C     C  D +   + C C  G+ G  C
Sbjct: 471  SGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 56/186 (30%), Positives = 71/186 (38%), Gaps = 25/186 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C---PVL----CSQRGEYINGECQCNP 928
            C NG S K +    HC C PG+ G  C  S   C   P      C +R +  N  C+C P
Sbjct: 333  CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPP 392

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFC--GEIDCPHPTCSGH 982
             + G  C  + D C    C   G C+N      C C  G+ G +C     DC    C+  
Sbjct: 393  NFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHG 452

Query: 983  GFC--IEG--TCVCKKGWKGADCGTMDK-DALQCLPDCSGHGT----FDVDTQTCSCHAK 1033
            G C  +E    C C  G+ G  C      DA    P C    T       DT  C+C   
Sbjct: 453  GTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP-CFNRATCYTDLSTDTFVCNCPYG 511

Query: 1034 WSGEDC 1039
            + G  C
Sbjct: 512  FVGSRC 517


>AY358891-1|AAQ89250.1|  737|Homo sapiens QPRR262 protein.
          Length = 737

 Score =  105 bits (251), Expect = 3e-21
 Identities = 86/301 (28%), Positives = 117/301 (38%), Gaps = 48/301 (15%)

Query: 882  CSGKGECLMG------HCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGE---C 924
            CSGKG+C          C C+  + G      D C +  C     C    E  +G    C
Sbjct: 319  CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTC 378

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CPHPT 978
             C PG+ G+ C  + D C +  C     C++      C C  GY G  C E +D C    
Sbjct: 379  VCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSP 438

Query: 979  CSGHGFC-IEG---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF-DVDTQ-TCSCHA 1032
            C  +G C ++G   TC C  G+ G  C  +       L  C+ HGT   V T   C C  
Sbjct: 439  CQNNGTCYVDGVHFTCNCSPGFTGPTCAQLID--FCALSPCA-HGTCRSVGTSYKCLCDP 495

Query: 1033 KWSGEDCSKEV--C-SLECGPHGRC----VGESCSCAAGWSGEFCSV---RLCDARCAEH 1082
             + G  C +E   C S  C     C     G  C C A + G  C +      +  C   
Sbjct: 496  GYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNG 555

Query: 1083 GQCK----NGTCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPD 1136
              C     NGTC+C  G+ G  C ++   C  +   HG   +D    + C C  GW G +
Sbjct: 556  ATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGAN 615

Query: 1137 C 1137
            C
Sbjct: 616  C 616



 Score = 93.1 bits (221), Expect = 1e-17
 Identities = 69/223 (30%), Positives = 94/223 (42%), Gaps = 29/223 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGE-YING---ECQCNPGW 930
            C NG +         CQC  G+ G  C + V P     C   G  Y++G    C C+PG+
Sbjct: 401  CRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGF 460

Query: 931  KGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGF 984
             G  C+   D C +  C  HG C     + KC C  GY G +C E   +C    C     
Sbjct: 461  TGPTCAQLIDFCALSPC-AHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAAT 519

Query: 985  C---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD--TQTCSCHAKWSGED 1038
            C   + G  CVC   +KG  C  + KD    +  C    T D D    TC C   ++GE+
Sbjct: 520  CRDLVNGYECVCLAEYKGTHC-ELYKDPCANV-SCLNGATCDSDGLNGTCICAPGFTGEE 577

Query: 1039 CSKEVCSLECGP--HG-RCV----GESCSCAAGWSGEFCSVRL 1074
            C  ++   +  P  HG  C+    G +C C  GW G  C + L
Sbjct: 578  CDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHL 620



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 74/245 (30%), Positives = 110/245 (44%), Gaps = 38/245 (15%)

Query: 893  CQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKECSLRHDECEVP 945
            C C PG+ G+ C   +  C +   + G      ++G  CQC  G+ G  C  + D C   
Sbjct: 378  CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437

Query: 946  DCNGHGHC----VNGKCSCVRGYKGKFCGE-ID-CPHPTCSGHGFCIE-GT---CVCKKG 995
             C  +G C    V+  C+C  G+ G  C + ID C    C+ HG C   GT   C+C  G
Sbjct: 438  PCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCA-HGTCRSVGTSYKCLCDPG 496

Query: 996  WKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS--KEVCS-LECG 1049
            + G  C   +++  +CL   C    T    V+   C C A++ G  C   K+ C+ + C 
Sbjct: 497  YHGLYC---EEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCL 553

Query: 1050 PHGRCVGE----SCSCAAGWSGEFCSVRL--CDARCAEHG-QC---KNG-TCLCVSGWNG 1098
                C  +    +C CA G++GE C + +  CD+    HG  C    NG  C C  GW G
Sbjct: 554  NGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVG 613

Query: 1099 RHCTL 1103
             +C +
Sbjct: 614  ANCEI 618



 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 26/152 (17%)

Query: 1014 DCSGHGTFDVD----TQTCSCHAKWSGEDCSK-EVCSLE-CGPHGRCVGES--------- 1058
            +CSG G         T +C+C  ++ G  C + + C  + C  +  C+  +         
Sbjct: 318  ECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFT 377

Query: 1059 CSCAAGWSGEFCSVRL--CDAR-CAEHGQCKNG----TCLCVSGWNGRHCT--LEGCPRS 1109
            C C  G++GE C  ++  C    C     C +     TC C  G+ G  C   ++ C  S
Sbjct: 378  CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437

Query: 1110 -CAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
             C  +G C VD    + C C  G+ GP C  L
Sbjct: 438  PCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQL 468



 Score = 41.5 bits (93), Expect = 0.045
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 7/68 (10%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPV-LCSQRGEYI---NG-ECQCNPG 929
           +C NG +   + L G C C PGF G++C   +  C    C   G  +   NG  C C  G
Sbjct: 551 SCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHG 610

Query: 930 WKGKECSL 937
           W G  C +
Sbjct: 611 WVGANCEI 618



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 5/54 (9%)

Query: 1089 TCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDGRWE---CKCFDGWDGPDC 1137
            +C C +G +G +C L  + C  +   HG C   +    +   C C +G++GP+C
Sbjct: 79   SCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 12/89 (13%)

Query: 891 GHCQCQPGFGGDDCSK--SVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCN 948
           G C  QP   G  C+      P   +  GE     C C  G  G  C L  D C    C+
Sbjct: 46  GPCAAQPCRNGGVCTSRPEPDPQHPAPAGEP-GYSCTCPAGISGANCQLVADPCASNPCH 104

Query: 949 GHGHCVNGK--------CSCVRGYKGKFC 969
            HG+C +          C C  GY+G  C
Sbjct: 105 -HGNCSSSSSSSSDGYLCICNEGYEGPNC 132



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 10/56 (17%)

Query: 1056 GESCSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT--------CLCVSGWNGRHC 1101
            G SC+C AG SG  C +    C +    HG C + +        C+C  G+ G +C
Sbjct: 77   GYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132


>AF442487-1|AAM21557.1|  737|Homo sapiens delta-notch-like EGF
            repeat-containing transmembrane protein protein.
          Length = 737

 Score =  105 bits (251), Expect = 3e-21
 Identities = 86/301 (28%), Positives = 117/301 (38%), Gaps = 48/301 (15%)

Query: 882  CSGKGECLMG------HCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGE---C 924
            CSGKG+C          C C+  + G      D C +  C     C    E  +G    C
Sbjct: 319  CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTC 378

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CPHPT 978
             C PG+ G+ C  + D C +  C     C++      C C  GY G  C E +D C    
Sbjct: 379  VCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSP 438

Query: 979  CSGHGFC-IEG---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF-DVDTQ-TCSCHA 1032
            C  +G C ++G   TC C  G+ G  C  +       L  C+ HGT   V T   C C  
Sbjct: 439  CQNNGTCYVDGVHFTCNCSPGFTGPTCAQLID--FCALSPCA-HGTCRSVGTSYKCLCDP 495

Query: 1033 KWSGEDCSKEV--C-SLECGPHGRC----VGESCSCAAGWSGEFCSV---RLCDARCAEH 1082
             + G  C +E   C S  C     C     G  C C A + G  C +      +  C   
Sbjct: 496  GYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNG 555

Query: 1083 GQCK----NGTCLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPD 1136
              C     NGTC+C  G+ G  C ++   C  +   HG   +D    + C C  GW G +
Sbjct: 556  ATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGAN 615

Query: 1137 C 1137
            C
Sbjct: 616  C 616



 Score = 93.1 bits (221), Expect = 1e-17
 Identities = 69/223 (30%), Positives = 94/223 (42%), Gaps = 29/223 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVL---CSQRGE-YING---ECQCNPGW 930
            C NG +         CQC  G+ G  C + V P     C   G  Y++G    C C+PG+
Sbjct: 401  CRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGF 460

Query: 931  KGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEI--DCPHPTCSGHGF 984
             G  C+   D C +  C  HG C     + KC C  GY G +C E   +C    C     
Sbjct: 461  TGPTCAQLIDFCALSPC-AHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAAT 519

Query: 985  C---IEG-TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD--TQTCSCHAKWSGED 1038
            C   + G  CVC   +KG  C  + KD    +  C    T D D    TC C   ++GE+
Sbjct: 520  CRDLVNGYECVCLAEYKGTHC-ELYKDPCANV-SCLNGATCDSDGLNGTCICAPGFTGEE 577

Query: 1039 CSKEVCSLECGP--HG-RCV----GESCSCAAGWSGEFCSVRL 1074
            C  ++   +  P  HG  C+    G +C C  GW G  C + L
Sbjct: 578  CDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHL 620



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 74/245 (30%), Positives = 110/245 (44%), Gaps = 38/245 (15%)

Query: 893  CQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKECSLRHDECEVP 945
            C C PG+ G+ C   +  C +   + G      ++G  CQC  G+ G  C  + D C   
Sbjct: 378  CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437

Query: 946  DCNGHGHC----VNGKCSCVRGYKGKFCGE-ID-CPHPTCSGHGFCIE-GT---CVCKKG 995
             C  +G C    V+  C+C  G+ G  C + ID C    C+ HG C   GT   C+C  G
Sbjct: 438  PCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCA-HGTCRSVGTSYKCLCDPG 496

Query: 996  WKGADCGTMDKDALQCLP-DCSGHGTFD--VDTQTCSCHAKWSGEDCS--KEVCS-LECG 1049
            + G  C   +++  +CL   C    T    V+   C C A++ G  C   K+ C+ + C 
Sbjct: 497  YHGLYC---EEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCL 553

Query: 1050 PHGRCVGE----SCSCAAGWSGEFCSVRL--CDARCAEHG-QC---KNG-TCLCVSGWNG 1098
                C  +    +C CA G++GE C + +  CD+    HG  C    NG  C C  GW G
Sbjct: 554  NGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVG 613

Query: 1099 RHCTL 1103
             +C +
Sbjct: 614  ANCEI 618



 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 26/152 (17%)

Query: 1014 DCSGHGTFDVD----TQTCSCHAKWSGEDCSK-EVCSLE-CGPHGRCVGES--------- 1058
            +CSG G         T +C+C  ++ G  C + + C  + C  +  C+  +         
Sbjct: 318  ECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFT 377

Query: 1059 CSCAAGWSGEFCSVRL--CDAR-CAEHGQCKNG----TCLCVSGWNGRHCT--LEGCPRS 1109
            C C  G++GE C  ++  C    C     C +     TC C  G+ G  C   ++ C  S
Sbjct: 378  CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437

Query: 1110 -CAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
             C  +G C VD    + C C  G+ GP C  L
Sbjct: 438  PCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQL 468



 Score = 41.5 bits (93), Expect = 0.045
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 7/68 (10%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPV-LCSQRGEYI---NG-ECQCNPG 929
           +C NG +   + L G C C PGF G++C   +  C    C   G  +   NG  C C  G
Sbjct: 551 SCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHG 610

Query: 930 WKGKECSL 937
           W G  C +
Sbjct: 611 WVGANCEI 618



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 5/54 (9%)

Query: 1089 TCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDGRWE---CKCFDGWDGPDC 1137
            +C C +G +G +C L  + C  +   HG C   +    +   C C +G++GP+C
Sbjct: 79   SCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132



 Score = 35.1 bits (77), Expect = 3.9
 Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 12/89 (13%)

Query: 891 GHCQCQPGFGGDDCSK--SVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCN 948
           G C  QP   G  C+      P   +  GE     C C  G  G  C L  D C    C+
Sbjct: 46  GPCAAQPCRNGGVCTSRPEPDPQHPAPAGEP-GYSCTCPAGISGANCQLVADPCASNPCH 104

Query: 949 GHGHCVNGK--------CSCVRGYKGKFC 969
            HG+C +          C C  GY+G  C
Sbjct: 105 -HGNCSSSSSSSSDGYLCICNEGYEGPNC 132



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 10/56 (17%)

Query: 1056 GESCSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT--------CLCVSGWNGRHC 1101
            G SC+C AG SG  C +    C +    HG C + +        C+C  G+ G +C
Sbjct: 77   GYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132


>AF279305-1|AAF81912.1|  653|Homo sapiens delta 4 protein.
          Length = 653

 Score =  105 bits (251), Expect = 3e-21
 Identities = 89/313 (28%), Positives = 128/313 (40%), Gaps = 43/313 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + GD+CS+ +C       G Y+   +G   C PGW G+ C  +   C       +G
Sbjct: 143  CSDNYYGDNCSR-LCKKRNDHFGHYVCQPDGNLSCLPGWTGEYC--QQPICLSGCHEQNG 199

Query: 952  HCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFC-IEGTCVCKKGWKGADCGTMDKDAL 1009
            +C    +C C  G++G+ C E   PH  C  HG C     C C +GW G  C   D+D  
Sbjct: 200  YCSKPAECLCRPGWQGRLCNEC-IPHNGCR-HGTCSTPWQCTCDEGWGGLFC---DQDLN 254

Query: 1010 QCL--PDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSLECGP---HGRCV----GE 1057
             C     C    T     Q   TC+C   ++G DC  E+   +  P    G C     G 
Sbjct: 255  YCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGY 314

Query: 1058 SCSCAAGWSGEFC---SVRLCDARCAEHGQCK------NGTCLCVSGWNGRHC--TLEGC 1106
             C C  G+ G  C   ++   D+ C   G C+      N  C C   + G +C   ++ C
Sbjct: 315  HCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRC 374

Query: 1107 PRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG--LVDCEDPE 1163
              + CA  GQC      R  C+C  G+ G  C   +  + D +R+    G    D E+  
Sbjct: 375  TSNPCANGGQCLNRGPSRM-CRCRPGFTGTYC---ELHVSDCARNPCAHGGTCHDLENGL 430

Query: 1164 CCQSPACKSSQLC 1176
             C  PA  S + C
Sbjct: 431  MCTCPAGFSGRRC 443



 Score =  103 bits (248), Expect = 7e-21
 Identities = 77/277 (27%), Positives = 113/277 (40%), Gaps = 35/277 (12%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCSQRGEYIN--GECQCNPGWKGKECSLRHDECEVPDCN 948
            G+  C PG+ G+ C + +C   C ++  Y +   EC C PGW+G+ C    +EC   +  
Sbjct: 172  GNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLC----NECIPHNGC 227

Query: 949  GHGHC-VNGKCSCVRGYKGKFCGE--IDCPHPT-CSGHGFCIEG-----TCVCKKGWKGA 999
             HG C    +C+C  G+ G FC +    C H + C     C        TC C+ G+ G 
Sbjct: 228  RHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGV 287

Query: 1000 DCGTMDKDALQCLPDCSGHGTFD-VDTQTCSC-------HAKWSGEDCSKEVC--SLECG 1049
            DC  ++       P  +G    D  D   C C       H + S   C+   C     C 
Sbjct: 288  DC-ELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCR 346

Query: 1050 PHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCKN----GTCLCVSGWNGRHCT 1102
               +    +C C   ++G  C  ++  C +  CA  GQC N      C C  G+ G +C 
Sbjct: 347  ERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCE 406

Query: 1103 L--EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L    C R+   HG    D +    C C  G+ G  C
Sbjct: 407  LHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRC 443



 Score = 84.2 bits (199), Expect = 6e-15
 Identities = 82/287 (28%), Positives = 118/287 (41%), Gaps = 55/287 (19%)

Query: 880  NGCSGKGECLMG-HCQCQPGFGGDDCSK--------SVCP--VLCSQRGEYINGECQCNP 928
            NGC   G C     C C  G+GG  C +        S C     CS  G+  +  C C P
Sbjct: 225  NGCR-HGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQR-SYTCTCRP 282

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEIDCPHPTCS-GHG 983
            G+ G +C L   EC+   C   G C + +    C C  GY G     + C H T S    
Sbjct: 283  GYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYG-----LHCEHSTLSCADS 337

Query: 984  FCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV 1043
             C  G   C++  +GA+       A +C P+ +G    +     C+ +   +G  C    
Sbjct: 338  PCFNGGS-CRERNQGANY------ACECPPNFTG-SNCEKKVDRCTSNPCANGGQC---- 385

Query: 1044 CSLECGPHGRCVGESCSCAAGWSGEFCSVRLCD-AR--CAEHGQC---KNG-TCLCVSGW 1096
              L  GP        C C  G++G +C + + D AR  CA  G C   +NG  C C +G+
Sbjct: 386  --LNRGP-----SRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGF 438

Query: 1097 NGRHC----TLEGCPRS-CAGHGQCRVD-NDGRWECKCFDGWDGPDC 1137
            +GR C    +++ C  S C     C  D +   + C C  G+ G  C
Sbjct: 439  SGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 485



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 56/186 (30%), Positives = 71/186 (38%), Gaps = 25/186 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C---PVL----CSQRGEYINGECQCNP 928
            C NG S K +    HC C PG+ G  C  S   C   P      C +R +  N  C+C P
Sbjct: 301  CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPP 360

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFC--GEIDCPHPTCSGH 982
             + G  C  + D C    C   G C+N      C C  G+ G +C     DC    C+  
Sbjct: 361  NFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHG 420

Query: 983  GFC--IEG--TCVCKKGWKGADCGTMDK-DALQCLPDCSGHGT----FDVDTQTCSCHAK 1033
            G C  +E    C C  G+ G  C      DA    P C    T       DT  C+C   
Sbjct: 421  GTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP-CFNRATCYTDLSTDTFVCNCPYG 479

Query: 1034 WSGEDC 1039
            + G  C
Sbjct: 480  FVGSRC 485


>AF253468-1|AAF76427.1|  685|Homo sapiens notch ligand DLL4 protein.
          Length = 685

 Score =  105 bits (251), Expect = 3e-21
 Identities = 89/313 (28%), Positives = 128/313 (40%), Gaps = 43/313 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + GD+CS+ +C       G Y+   +G   C PGW G+ C  +   C       +G
Sbjct: 175  CSDNYYGDNCSR-LCKKRNDHFGHYVCQPDGNLSCLPGWTGEYC--QQPICLSGCHEQNG 231

Query: 952  HCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFC-IEGTCVCKKGWKGADCGTMDKDAL 1009
            +C    +C C  G++G+ C E   PH  C  HG C     C C +GW G  C   D+D  
Sbjct: 232  YCSKPAECLCRPGWQGRLCNEC-IPHNGCR-HGTCSTPWQCTCDEGWGGLFC---DQDLN 286

Query: 1010 QCL--PDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSLECGP---HGRCV----GE 1057
             C     C    T     Q   TC+C   ++G DC  E+   +  P    G C     G 
Sbjct: 287  YCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGY 346

Query: 1058 SCSCAAGWSGEFC---SVRLCDARCAEHGQCK------NGTCLCVSGWNGRHC--TLEGC 1106
             C C  G+ G  C   ++   D+ C   G C+      N  C C   + G +C   ++ C
Sbjct: 347  HCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRC 406

Query: 1107 PRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG--LVDCEDPE 1163
              + CA  GQC      R  C+C  G+ G  C   +  + D +R+    G    D E+  
Sbjct: 407  TSNPCANGGQCLNRGPSRM-CRCRPGFTGTYC---ELHVSDCARNPCAHGGTCHDLENGL 462

Query: 1164 CCQSPACKSSQLC 1176
             C  PA  S + C
Sbjct: 463  MCTCPAGFSGRRC 475



 Score =  103 bits (248), Expect = 7e-21
 Identities = 77/277 (27%), Positives = 113/277 (40%), Gaps = 35/277 (12%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCSQRGEYIN--GECQCNPGWKGKECSLRHDECEVPDCN 948
            G+  C PG+ G+ C + +C   C ++  Y +   EC C PGW+G+ C    +EC   +  
Sbjct: 204  GNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLC----NECIPHNGC 259

Query: 949  GHGHC-VNGKCSCVRGYKGKFCGE--IDCPHPT-CSGHGFCIEG-----TCVCKKGWKGA 999
             HG C    +C+C  G+ G FC +    C H + C     C        TC C+ G+ G 
Sbjct: 260  RHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGV 319

Query: 1000 DCGTMDKDALQCLPDCSGHGTFD-VDTQTCSC-------HAKWSGEDCSKEVC--SLECG 1049
            DC  ++       P  +G    D  D   C C       H + S   C+   C     C 
Sbjct: 320  DC-ELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCR 378

Query: 1050 PHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCKN----GTCLCVSGWNGRHCT 1102
               +    +C C   ++G  C  ++  C +  CA  GQC N      C C  G+ G +C 
Sbjct: 379  ERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCE 438

Query: 1103 L--EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L    C R+   HG    D +    C C  G+ G  C
Sbjct: 439  LHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRC 475



 Score = 84.2 bits (199), Expect = 6e-15
 Identities = 82/287 (28%), Positives = 118/287 (41%), Gaps = 55/287 (19%)

Query: 880  NGCSGKGECLMG-HCQCQPGFGGDDCSK--------SVCP--VLCSQRGEYINGECQCNP 928
            NGC   G C     C C  G+GG  C +        S C     CS  G+  +  C C P
Sbjct: 257  NGCR-HGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQR-SYTCTCRP 314

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEIDCPHPTCS-GHG 983
            G+ G +C L   EC+   C   G C + +    C C  GY G     + C H T S    
Sbjct: 315  GYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYG-----LHCEHSTLSCADS 369

Query: 984  FCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV 1043
             C  G   C++  +GA+       A +C P+ +G    +     C+ +   +G  C    
Sbjct: 370  PCFNGGS-CRERNQGANY------ACECPPNFTG-SNCEKKVDRCTSNPCANGGQC---- 417

Query: 1044 CSLECGPHGRCVGESCSCAAGWSGEFCSVRLCD-AR--CAEHGQC---KNG-TCLCVSGW 1096
              L  GP        C C  G++G +C + + D AR  CA  G C   +NG  C C +G+
Sbjct: 418  --LNRGP-----SRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGF 470

Query: 1097 NGRHC----TLEGCPRS-CAGHGQCRVD-NDGRWECKCFDGWDGPDC 1137
            +GR C    +++ C  S C     C  D +   + C C  G+ G  C
Sbjct: 471  SGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 56/186 (30%), Positives = 71/186 (38%), Gaps = 25/186 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C---PVL----CSQRGEYINGECQCNP 928
            C NG S K +    HC C PG+ G  C  S   C   P      C +R +  N  C+C P
Sbjct: 333  CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPP 392

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFC--GEIDCPHPTCSGH 982
             + G  C  + D C    C   G C+N      C C  G+ G +C     DC    C+  
Sbjct: 393  NFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHG 452

Query: 983  GFC--IEG--TCVCKKGWKGADCGTMDK-DALQCLPDCSGHGT----FDVDTQTCSCHAK 1033
            G C  +E    C C  G+ G  C      DA    P C    T       DT  C+C   
Sbjct: 453  GTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP-CFNRATCYTDLSTDTFVCNCPYG 511

Query: 1034 WSGEDC 1039
            + G  C
Sbjct: 512  FVGSRC 517


>AB043894-1|BAB18581.1|  685|Homo sapiens Delta-4 protein.
          Length = 685

 Score =  105 bits (251), Expect = 3e-21
 Identities = 89/313 (28%), Positives = 128/313 (40%), Gaps = 43/313 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + GD+CS+ +C       G Y+   +G   C PGW G+ C  +   C       +G
Sbjct: 175  CSDNYYGDNCSR-LCKKRNDHFGHYVCQPDGNLSCLPGWTGEYC--QQPICLSGCHEQNG 231

Query: 952  HCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFC-IEGTCVCKKGWKGADCGTMDKDAL 1009
            +C    +C C  G++G+ C E   PH  C  HG C     C C +GW G  C   D+D  
Sbjct: 232  YCSKPAECLCRPGWQGRLCNEC-IPHNGCR-HGTCSTPWQCTCDEGWGGLFC---DQDLN 286

Query: 1010 QCL--PDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSLECGP---HGRCV----GE 1057
             C     C    T     Q   TC+C   ++G DC  E+   +  P    G C     G 
Sbjct: 287  YCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGY 346

Query: 1058 SCSCAAGWSGEFC---SVRLCDARCAEHGQCK------NGTCLCVSGWNGRHC--TLEGC 1106
             C C  G+ G  C   ++   D+ C   G C+      N  C C   + G +C   ++ C
Sbjct: 347  HCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRC 406

Query: 1107 PRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG--LVDCEDPE 1163
              + CA  GQC      R  C+C  G+ G  C   +  + D +R+    G    D E+  
Sbjct: 407  TSNPCANGGQCLNRGPSRM-CRCRPGFTGTYC---ELHVSDCARNPCAHGGTCHDLENGL 462

Query: 1164 CCQSPACKSSQLC 1176
             C  PA  S + C
Sbjct: 463  MCTCPAGFSGRRC 475



 Score =  103 bits (248), Expect = 7e-21
 Identities = 77/277 (27%), Positives = 113/277 (40%), Gaps = 35/277 (12%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCSQRGEYIN--GECQCNPGWKGKECSLRHDECEVPDCN 948
            G+  C PG+ G+ C + +C   C ++  Y +   EC C PGW+G+ C    +EC   +  
Sbjct: 204  GNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLC----NECIPHNGC 259

Query: 949  GHGHC-VNGKCSCVRGYKGKFCGE--IDCPHPT-CSGHGFCIEG-----TCVCKKGWKGA 999
             HG C    +C+C  G+ G FC +    C H + C     C        TC C+ G+ G 
Sbjct: 260  RHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGV 319

Query: 1000 DCGTMDKDALQCLPDCSGHGTFD-VDTQTCSC-------HAKWSGEDCSKEVC--SLECG 1049
            DC  ++       P  +G    D  D   C C       H + S   C+   C     C 
Sbjct: 320  DC-ELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCR 378

Query: 1050 PHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCKN----GTCLCVSGWNGRHCT 1102
               +    +C C   ++G  C  ++  C +  CA  GQC N      C C  G+ G +C 
Sbjct: 379  ERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCE 438

Query: 1103 L--EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L    C R+   HG    D +    C C  G+ G  C
Sbjct: 439  LHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRC 475



 Score = 84.2 bits (199), Expect = 6e-15
 Identities = 82/287 (28%), Positives = 118/287 (41%), Gaps = 55/287 (19%)

Query: 880  NGCSGKGECLMG-HCQCQPGFGGDDCSK--------SVCP--VLCSQRGEYINGECQCNP 928
            NGC   G C     C C  G+GG  C +        S C     CS  G+  +  C C P
Sbjct: 257  NGCR-HGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQR-SYTCTCRP 314

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEIDCPHPTCS-GHG 983
            G+ G +C L   EC+   C   G C + +    C C  GY G     + C H T S    
Sbjct: 315  GYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYG-----LHCEHSTLSCADS 369

Query: 984  FCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV 1043
             C  G   C++  +GA+       A +C P+ +G    +     C+ +   +G  C    
Sbjct: 370  PCFNGGS-CRERNQGANY------ACECPPNFTG-SNCEKKVDRCTSNPCANGGQC---- 417

Query: 1044 CSLECGPHGRCVGESCSCAAGWSGEFCSVRLCD-AR--CAEHGQC---KNG-TCLCVSGW 1096
              L  GP        C C  G++G +C + + D AR  CA  G C   +NG  C C +G+
Sbjct: 418  --LNRGP-----SRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGF 470

Query: 1097 NGRHC----TLEGCPRS-CAGHGQCRVD-NDGRWECKCFDGWDGPDC 1137
            +GR C    +++ C  S C     C  D +   + C C  G+ G  C
Sbjct: 471  SGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 56/186 (30%), Positives = 71/186 (38%), Gaps = 25/186 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C---PVL----CSQRGEYINGECQCNP 928
            C NG S K +    HC C PG+ G  C  S   C   P      C +R +  N  C+C P
Sbjct: 333  CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPP 392

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFC--GEIDCPHPTCSGH 982
             + G  C  + D C    C   G C+N      C C  G+ G +C     DC    C+  
Sbjct: 393  NFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHG 452

Query: 983  GFC--IEG--TCVCKKGWKGADCGTMDK-DALQCLPDCSGHGT----FDVDTQTCSCHAK 1033
            G C  +E    C C  G+ G  C      DA    P C    T       DT  C+C   
Sbjct: 453  GTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP-CFNRATCYTDLSTDTFVCNCPYG 511

Query: 1034 WSGEDC 1039
            + G  C
Sbjct: 512  FVGSRC 517


>AB036931-1|BAB16085.1|  685|Homo sapiens notch ligand delta-2
            protein.
          Length = 685

 Score =  105 bits (251), Expect = 3e-21
 Identities = 89/313 (28%), Positives = 128/313 (40%), Gaps = 43/313 (13%)

Query: 895  CQPGFGGDDCSKSVCPVLCSQRGEYI---NGECQCNPGWKGKECSLRHDECEVPDCNGHG 951
            C   + GD+CS+ +C       G Y+   +G   C PGW G+ C  +   C       +G
Sbjct: 175  CSDNYYGDNCSR-LCKKRNDHFGHYVCQPDGNLSCLPGWTGEYC--QQPICLSGCHEQNG 231

Query: 952  HCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFC-IEGTCVCKKGWKGADCGTMDKDAL 1009
            +C    +C C  G++G+ C E   PH  C  HG C     C C +GW G  C   D+D  
Sbjct: 232  YCSKPAECLCRPGWQGRLCNEC-IPHNGCR-HGTCSTPWQCTCDEGWGGLFC---DQDLN 286

Query: 1010 QCL--PDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSLECGP---HGRCV----GE 1057
             C     C    T     Q   TC+C   ++G DC  E+   +  P    G C     G 
Sbjct: 287  YCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGY 346

Query: 1058 SCSCAAGWSGEFC---SVRLCDARCAEHGQCK------NGTCLCVSGWNGRHC--TLEGC 1106
             C C  G+ G  C   ++   D+ C   G C+      N  C C   + G +C   ++ C
Sbjct: 347  HCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRC 406

Query: 1107 PRS-CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDG--LVDCEDPE 1163
              + CA  GQC      R  C+C  G+ G  C   +  + D +R+    G    D E+  
Sbjct: 407  TSNPCANGGQCLNRGPSRM-CRCRPGFTGTYC---ELHVSDCARNPCAHGGTCHDLENGL 462

Query: 1164 CCQSPACKSSQLC 1176
             C  PA  S + C
Sbjct: 463  MCTCPAGFSGRRC 475



 Score =  103 bits (248), Expect = 7e-21
 Identities = 77/277 (27%), Positives = 113/277 (40%), Gaps = 35/277 (12%)

Query: 891  GHCQCQPGFGGDDCSKSVCPVLCSQRGEYIN--GECQCNPGWKGKECSLRHDECEVPDCN 948
            G+  C PG+ G+ C + +C   C ++  Y +   EC C PGW+G+ C    +EC   +  
Sbjct: 204  GNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLC----NECIPHNGC 259

Query: 949  GHGHC-VNGKCSCVRGYKGKFCGE--IDCPHPT-CSGHGFCIEG-----TCVCKKGWKGA 999
             HG C    +C+C  G+ G FC +    C H + C     C        TC C+ G+ G 
Sbjct: 260  RHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGV 319

Query: 1000 DCGTMDKDALQCLPDCSGHGTFD-VDTQTCSC-------HAKWSGEDCSKEVC--SLECG 1049
            DC  ++       P  +G    D  D   C C       H + S   C+   C     C 
Sbjct: 320  DC-ELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCR 378

Query: 1050 PHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCKN----GTCLCVSGWNGRHCT 1102
               +    +C C   ++G  C  ++  C +  CA  GQC N      C C  G+ G +C 
Sbjct: 379  ERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCE 438

Query: 1103 L--EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L    C R+   HG    D +    C C  G+ G  C
Sbjct: 439  LHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRC 475



 Score = 84.2 bits (199), Expect = 6e-15
 Identities = 82/287 (28%), Positives = 118/287 (41%), Gaps = 55/287 (19%)

Query: 880  NGCSGKGECLMG-HCQCQPGFGGDDCSK--------SVCP--VLCSQRGEYINGECQCNP 928
            NGC   G C     C C  G+GG  C +        S C     CS  G+  +  C C P
Sbjct: 257  NGCR-HGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQR-SYTCTCRP 314

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFCGEIDCPHPTCS-GHG 983
            G+ G +C L   EC+   C   G C + +    C C  GY G     + C H T S    
Sbjct: 315  GYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYG-----LHCEHSTLSCADS 369

Query: 984  FCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV 1043
             C  G   C++  +GA+       A +C P+ +G    +     C+ +   +G  C    
Sbjct: 370  PCFNGGS-CRERNQGANY------ACECPPNFTG-SNCEKKVDRCTSNPCANGGQC---- 417

Query: 1044 CSLECGPHGRCVGESCSCAAGWSGEFCSVRLCD-AR--CAEHGQC---KNG-TCLCVSGW 1096
              L  GP        C C  G++G +C + + D AR  CA  G C   +NG  C C +G+
Sbjct: 418  --LNRGP-----SRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGF 470

Query: 1097 NGRHC----TLEGCPRS-CAGHGQCRVD-NDGRWECKCFDGWDGPDC 1137
            +GR C    +++ C  S C     C  D +   + C C  G+ G  C
Sbjct: 471  SGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 56/186 (30%), Positives = 71/186 (38%), Gaps = 25/186 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C---PVL----CSQRGEYINGECQCNP 928
            C NG S K +    HC C PG+ G  C  S   C   P      C +R +  N  C+C P
Sbjct: 333  CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPP 392

Query: 929  GWKGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFC--GEIDCPHPTCSGH 982
             + G  C  + D C    C   G C+N      C C  G+ G +C     DC    C+  
Sbjct: 393  NFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHG 452

Query: 983  GFC--IEG--TCVCKKGWKGADCGTMDK-DALQCLPDCSGHGT----FDVDTQTCSCHAK 1033
            G C  +E    C C  G+ G  C      DA    P C    T       DT  C+C   
Sbjct: 453  GTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP-CFNRATCYTDLSTDTFVCNCPYG 511

Query: 1034 WSGEDC 1039
            + G  C
Sbjct: 512  FVGSRC 517


>BC036788-1|AAH36788.2|  494|Homo sapiens integrin, beta-like 1 (with
            EGF-like repeat domains) protein.
          Length = 494

 Score =  103 bits (248), Expect = 7e-21
 Identities = 99/334 (29%), Positives = 125/334 (37%), Gaps = 54/334 (16%)

Query: 882  CSGKGECLMGHCQC---QPG-FGGD--DCSKSVCPVL----CSQRGEYINGECQCNPGWK 931
            C G+G C  G C C   +PG F G   +C + VC       C+  G+   G+C+C+ GW 
Sbjct: 63   CHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGWY 122

Query: 932  GKECSL----------RHDECEVPD---CNGHGHCVNGKCSCVRG-----YKGKFC--GE 971
            G  C             +  C+      C+  G C  G+C C          GKFC   +
Sbjct: 123  GDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDD 182

Query: 972  IDC----PHPTCSGHGFCIEGTCVCKKGWKGADCG-TMDKDALQCLPDC-SGHGTFDVDT 1025
             +C        C GHG C  G C CK GW G  C    D    +    C S  G    + 
Sbjct: 183  RECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNR 242

Query: 1026 QTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQC 1085
             TC C     GE    +V     G  G   G++C C           R  D  C+ HGQC
Sbjct: 243  GTCVC-----GECTCHDVD--PTGDWGDIHGDTCECDER-DCRAVYDRYSDDFCSGHGQC 294

Query: 1086 KNGTCLCVSGWNGRHC--------TLEGCPRSCAGHGQCRVDNDGRWEC-KCFDGWDGPD 1136
              G C C +GW G+ C        + E   R C G         G+ EC KC     G  
Sbjct: 295  NCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDR 354

Query: 1137 CTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
                K   CDD R  D DG+V C     C    C
Sbjct: 355  RVYGKTCECDDRRCEDLDGVV-CGGHGTCSCGRC 387



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 81/257 (31%), Positives = 106/257 (41%), Gaps = 62/257 (24%)

Query: 879  PNG--CSGKGECLMGHCQCQP----GFGGD------DCSKSVCPVL--------CSQRGE 918
            P+G  CS +G C+ G C C      G  GD      +C +  C  +        CS  G+
Sbjct: 234  PDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQ 293

Query: 919  YINGECQCNPGWKGKEC------SLRHDE----CEVPD---CNGHGHCVNGKCSCV---- 961
               G C C  GW GK+C      +L  +E    C+      C+G G C  GKC+C     
Sbjct: 294  CNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGD 353

Query: 962  RGYKGKFCGEID--CPH---PTCSGHGFCIEGTCVCKKGWKGADCG-----TMDKDALQC 1011
            R   GK C   D  C       C GHG C  G CVC++GW G  C       M ++  + 
Sbjct: 354  RRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQHPRKCNMTEEQSKN 413

Query: 1012 LPD------CSGHGTFDVDTQTCSCHAKW--SGE--DCSKEVCS----LECGPHGRCVGE 1057
            L +      CSG G+       CS   +W  SGE  DC    C     L C  +G C   
Sbjct: 414  LCESADGILCSGKGSCHCGKCICSAE-EWYISGEFCDCDDRDCDKHDGLICTGNGICSCG 472

Query: 1058 SCSCAAGWSGEFCSVRL 1074
            +C C  GW+G  C + L
Sbjct: 473  NCECWDGWNGNACEIWL 489


>AL355807-1|CAI14550.1|  494|Homo sapiens integrin, beta-like 1 (with
            EGF-like repeat domains) protein.
          Length = 494

 Score =  103 bits (248), Expect = 7e-21
 Identities = 99/334 (29%), Positives = 125/334 (37%), Gaps = 54/334 (16%)

Query: 882  CSGKGECLMGHCQC---QPG-FGGD--DCSKSVCPVL----CSQRGEYINGECQCNPGWK 931
            C G+G C  G C C   +PG F G   +C + VC       C+  G+   G+C+C+ GW 
Sbjct: 63   CHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGWY 122

Query: 932  GKECSL----------RHDECEVPD---CNGHGHCVNGKCSCVRG-----YKGKFC--GE 971
            G  C             +  C+      C+  G C  G+C C          GKFC   +
Sbjct: 123  GDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDD 182

Query: 972  IDC----PHPTCSGHGFCIEGTCVCKKGWKGADCG-TMDKDALQCLPDC-SGHGTFDVDT 1025
             +C        C GHG C  G C CK GW G  C    D    +    C S  G    + 
Sbjct: 183  RECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNR 242

Query: 1026 QTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQC 1085
             TC C     GE    +V     G  G   G++C C           R  D  C+ HGQC
Sbjct: 243  GTCVC-----GECTCHDVD--PTGDWGDIHGDTCECDER-DCRAVYDRYSDDFCSGHGQC 294

Query: 1086 KNGTCLCVSGWNGRHC--------TLEGCPRSCAGHGQCRVDNDGRWEC-KCFDGWDGPD 1136
              G C C +GW G+ C        + E   R C G         G+ EC KC     G  
Sbjct: 295  NCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDR 354

Query: 1137 CTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
                K   CDD R  D DG+V C     C    C
Sbjct: 355  RVYGKTCECDDRRCEDLDGVV-CGGHGTCSCGRC 387



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 81/257 (31%), Positives = 106/257 (41%), Gaps = 62/257 (24%)

Query: 879  PNG--CSGKGECLMGHCQCQP----GFGGD------DCSKSVCPVL--------CSQRGE 918
            P+G  CS +G C+ G C C      G  GD      +C +  C  +        CS  G+
Sbjct: 234  PDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQ 293

Query: 919  YINGECQCNPGWKGKEC------SLRHDE----CEVPD---CNGHGHCVNGKCSCV---- 961
               G C C  GW GK+C      +L  +E    C+      C+G G C  GKC+C     
Sbjct: 294  CNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGD 353

Query: 962  RGYKGKFCGEID--CPH---PTCSGHGFCIEGTCVCKKGWKGADCG-----TMDKDALQC 1011
            R   GK C   D  C       C GHG C  G CVC++GW G  C       M ++  + 
Sbjct: 354  RRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQHPRKCNMTEEQSKN 413

Query: 1012 LPD------CSGHGTFDVDTQTCSCHAKW--SGE--DCSKEVCS----LECGPHGRCVGE 1057
            L +      CSG G+       CS   +W  SGE  DC    C     L C  +G C   
Sbjct: 414  LCESADGILCSGKGSCHCGKCICSAE-EWYISGEFCDCDDRDCDKHDGLICTGNGICSCG 472

Query: 1058 SCSCAAGWSGEFCSVRL 1074
            +C C  GW+G  C + L
Sbjct: 473  NCECWDGWNGNACEIWL 489


>AL160153-1|CAH73400.1|  494|Homo sapiens integrin, beta-like 1 (with
            EGF-like repeat domains) protein.
          Length = 494

 Score =  103 bits (248), Expect = 7e-21
 Identities = 99/334 (29%), Positives = 125/334 (37%), Gaps = 54/334 (16%)

Query: 882  CSGKGECLMGHCQC---QPG-FGGD--DCSKSVCPVL----CSQRGEYINGECQCNPGWK 931
            C G+G C  G C C   +PG F G   +C + VC       C+  G+   G+C+C+ GW 
Sbjct: 63   CHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGWY 122

Query: 932  GKECSL----------RHDECEVPD---CNGHGHCVNGKCSCVRG-----YKGKFC--GE 971
            G  C             +  C+      C+  G C  G+C C          GKFC   +
Sbjct: 123  GDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDD 182

Query: 972  IDC----PHPTCSGHGFCIEGTCVCKKGWKGADCG-TMDKDALQCLPDC-SGHGTFDVDT 1025
             +C        C GHG C  G C CK GW G  C    D    +    C S  G    + 
Sbjct: 183  RECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNR 242

Query: 1026 QTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQC 1085
             TC C     GE    +V     G  G   G++C C           R  D  C+ HGQC
Sbjct: 243  GTCVC-----GECTCHDVD--PTGDWGDIHGDTCECDER-DCRAVYDRYSDDFCSGHGQC 294

Query: 1086 KNGTCLCVSGWNGRHC--------TLEGCPRSCAGHGQCRVDNDGRWEC-KCFDGWDGPD 1136
              G C C +GW G+ C        + E   R C G         G+ EC KC     G  
Sbjct: 295  NCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDR 354

Query: 1137 CTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
                K   CDD R  D DG+V C     C    C
Sbjct: 355  RVYGKTCECDDRRCEDLDGVV-CGGHGTCSCGRC 387



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 81/257 (31%), Positives = 106/257 (41%), Gaps = 62/257 (24%)

Query: 879  PNG--CSGKGECLMGHCQCQP----GFGGD------DCSKSVCPVL--------CSQRGE 918
            P+G  CS +G C+ G C C      G  GD      +C +  C  +        CS  G+
Sbjct: 234  PDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQ 293

Query: 919  YINGECQCNPGWKGKEC------SLRHDE----CEVPD---CNGHGHCVNGKCSCV---- 961
               G C C  GW GK+C      +L  +E    C+      C+G G C  GKC+C     
Sbjct: 294  CNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGD 353

Query: 962  RGYKGKFCGEID--CPH---PTCSGHGFCIEGTCVCKKGWKGADCG-----TMDKDALQC 1011
            R   GK C   D  C       C GHG C  G CVC++GW G  C       M ++  + 
Sbjct: 354  RRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQHPRKCNMTEEQSKN 413

Query: 1012 LPD------CSGHGTFDVDTQTCSCHAKW--SGE--DCSKEVCS----LECGPHGRCVGE 1057
            L +      CSG G+       CS   +W  SGE  DC    C     L C  +G C   
Sbjct: 414  LCESADGILCSGKGSCHCGKCICSAE-EWYISGEFCDCDDRDCDKHDGLICTGNGICSCG 472

Query: 1058 SCSCAAGWSGEFCSVRL 1074
            +C C  GW+G  C + L
Sbjct: 473  NCECWDGWNGNACEIWL 489


>AL139800-1|CAH71455.1|  494|Homo sapiens integrin, beta-like 1 (with
            EGF-like repeat domains) protein.
          Length = 494

 Score =  103 bits (248), Expect = 7e-21
 Identities = 99/334 (29%), Positives = 125/334 (37%), Gaps = 54/334 (16%)

Query: 882  CSGKGECLMGHCQC---QPG-FGGD--DCSKSVCPVL----CSQRGEYINGECQCNPGWK 931
            C G+G C  G C C   +PG F G   +C + VC       C+  G+   G+C+C+ GW 
Sbjct: 63   CHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGWY 122

Query: 932  GKECSL----------RHDECEVPD---CNGHGHCVNGKCSCVRG-----YKGKFC--GE 971
            G  C             +  C+      C+  G C  G+C C          GKFC   +
Sbjct: 123  GDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDD 182

Query: 972  IDC----PHPTCSGHGFCIEGTCVCKKGWKGADCG-TMDKDALQCLPDC-SGHGTFDVDT 1025
             +C        C GHG C  G C CK GW G  C    D    +    C S  G    + 
Sbjct: 183  RECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNR 242

Query: 1026 QTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQC 1085
             TC C     GE    +V     G  G   G++C C           R  D  C+ HGQC
Sbjct: 243  GTCVC-----GECTCHDVD--PTGDWGDIHGDTCECDER-DCRAVYDRYSDDFCSGHGQC 294

Query: 1086 KNGTCLCVSGWNGRHC--------TLEGCPRSCAGHGQCRVDNDGRWEC-KCFDGWDGPD 1136
              G C C +GW G+ C        + E   R C G         G+ EC KC     G  
Sbjct: 295  NCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDR 354

Query: 1137 CTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
                K   CDD R  D DG+V C     C    C
Sbjct: 355  RVYGKTCECDDRRCEDLDGVV-CGGHGTCSCGRC 387



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 81/257 (31%), Positives = 106/257 (41%), Gaps = 62/257 (24%)

Query: 879  PNG--CSGKGECLMGHCQCQP----GFGGD------DCSKSVCPVL--------CSQRGE 918
            P+G  CS +G C+ G C C      G  GD      +C +  C  +        CS  G+
Sbjct: 234  PDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQ 293

Query: 919  YINGECQCNPGWKGKEC------SLRHDE----CEVPD---CNGHGHCVNGKCSCV---- 961
               G C C  GW GK+C      +L  +E    C+      C+G G C  GKC+C     
Sbjct: 294  CNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGD 353

Query: 962  RGYKGKFCGEID--CPH---PTCSGHGFCIEGTCVCKKGWKGADCG-----TMDKDALQC 1011
            R   GK C   D  C       C GHG C  G CVC++GW G  C       M ++  + 
Sbjct: 354  RRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQHPRKCNMTEEQSKN 413

Query: 1012 LPD------CSGHGTFDVDTQTCSCHAKW--SGE--DCSKEVCS----LECGPHGRCVGE 1057
            L +      CSG G+       CS   +W  SGE  DC    C     L C  +G C   
Sbjct: 414  LCESADGILCSGKGSCHCGKCICSAE-EWYISGEFCDCDDRDCDKHDGLICTGNGICSCG 472

Query: 1058 SCSCAAGWSGEFCSVRL 1074
            +C C  GW+G  C + L
Sbjct: 473  NCECWDGWNGNACEIWL 489


>AF072752-1|AAD17666.1|  494|Homo sapiens ten integrin EGF-like repeat
            domains protein precursor protein.
          Length = 494

 Score =  103 bits (248), Expect = 7e-21
 Identities = 99/334 (29%), Positives = 125/334 (37%), Gaps = 54/334 (16%)

Query: 882  CSGKGECLMGHCQC---QPG-FGGD--DCSKSVCPVL----CSQRGEYINGECQCNPGWK 931
            C G+G C  G C C   +PG F G   +C + VC       C+  G+   G+C+C+ GW 
Sbjct: 63   CHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGWY 122

Query: 932  GKECSL----------RHDECEVPD---CNGHGHCVNGKCSCVRG-----YKGKFC--GE 971
            G  C             +  C+      C+  G C  G+C C          GKFC   +
Sbjct: 123  GDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDD 182

Query: 972  IDC----PHPTCSGHGFCIEGTCVCKKGWKGADCG-TMDKDALQCLPDC-SGHGTFDVDT 1025
             +C        C GHG C  G C CK GW G  C    D    +    C S  G    + 
Sbjct: 183  RECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNR 242

Query: 1026 QTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQC 1085
             TC C     GE    +V     G  G   G++C C           R  D  C+ HGQC
Sbjct: 243  GTCVC-----GECTCHDVD--PTGDWGDIHGDTCECDER-DCRAVYDRYSDDFCSGHGQC 294

Query: 1086 KNGTCLCVSGWNGRHC--------TLEGCPRSCAGHGQCRVDNDGRWEC-KCFDGWDGPD 1136
              G C C +GW G+ C        + E   R C G         G+ EC KC     G  
Sbjct: 295  NCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDR 354

Query: 1137 CTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
                K   CDD R  D DG+V C     C    C
Sbjct: 355  RVYGKTCECDDRRCEDLDGVV-CGGHGTCSCGRC 387



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 81/257 (31%), Positives = 106/257 (41%), Gaps = 62/257 (24%)

Query: 879  PNG--CSGKGECLMGHCQCQP----GFGGD------DCSKSVCPVL--------CSQRGE 918
            P+G  CS +G C+ G C C      G  GD      +C +  C  +        CS  G+
Sbjct: 234  PDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQ 293

Query: 919  YINGECQCNPGWKGKEC------SLRHDE----CEVPD---CNGHGHCVNGKCSCV---- 961
               G C C  GW GK+C      +L  +E    C+      C+G G C  GKC+C     
Sbjct: 294  CNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGD 353

Query: 962  RGYKGKFCGEID--CPH---PTCSGHGFCIEGTCVCKKGWKGADCG-----TMDKDALQC 1011
            R   GK C   D  C       C GHG C  G CVC++GW G  C       M ++  + 
Sbjct: 354  RRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQHPRKCNMTEEQSKN 413

Query: 1012 LPD------CSGHGTFDVDTQTCSCHAKW--SGE--DCSKEVCS----LECGPHGRCVGE 1057
            L +      CSG G+       CS   +W  SGE  DC    C     L C  +G C   
Sbjct: 414  LCESADGILCSGKGSCHCGKCICSAE-EWYISGEFCDCDDRDCDKHDGLICTGNGICSCG 472

Query: 1058 SCSCAAGWSGEFCSVRL 1074
            +C C  GW+G  C + L
Sbjct: 473  NCECWDGWNGNACEIWL 489


>AE014302-1|AAN16024.1|  494|Homo sapiens ITGBL1 protein.
          Length = 494

 Score =  103 bits (248), Expect = 7e-21
 Identities = 99/334 (29%), Positives = 125/334 (37%), Gaps = 54/334 (16%)

Query: 882  CSGKGECLMGHCQC---QPG-FGGD--DCSKSVCPVL----CSQRGEYINGECQCNPGWK 931
            C G+G C  G C C   +PG F G   +C + VC       C+  G+   G+C+C+ GW 
Sbjct: 63   CHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGWY 122

Query: 932  GKECSL----------RHDECEVPD---CNGHGHCVNGKCSCVRG-----YKGKFC--GE 971
            G  C             +  C+      C+  G C  G+C C          GKFC   +
Sbjct: 123  GDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDD 182

Query: 972  IDC----PHPTCSGHGFCIEGTCVCKKGWKGADCG-TMDKDALQCLPDC-SGHGTFDVDT 1025
             +C        C GHG C  G C CK GW G  C    D    +    C S  G    + 
Sbjct: 183  RECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNR 242

Query: 1026 QTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQC 1085
             TC C     GE    +V     G  G   G++C C           R  D  C+ HGQC
Sbjct: 243  GTCVC-----GECTCHDVD--PTGDWGDIHGDTCECDER-DCRAVYDRYSDDFCSGHGQC 294

Query: 1086 KNGTCLCVSGWNGRHC--------TLEGCPRSCAGHGQCRVDNDGRWEC-KCFDGWDGPD 1136
              G C C +GW G+ C        + E   R C G         G+ EC KC     G  
Sbjct: 295  NCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDR 354

Query: 1137 CTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
                K   CDD R  D DG+V C     C    C
Sbjct: 355  RVYGKTCECDDRRCEDLDGVV-CGGHGTCSCGRC 387



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 81/257 (31%), Positives = 106/257 (41%), Gaps = 62/257 (24%)

Query: 879  PNG--CSGKGECLMGHCQCQP----GFGGD------DCSKSVCPVL--------CSQRGE 918
            P+G  CS +G C+ G C C      G  GD      +C +  C  +        CS  G+
Sbjct: 234  PDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQ 293

Query: 919  YINGECQCNPGWKGKEC------SLRHDE----CEVPD---CNGHGHCVNGKCSCV---- 961
               G C C  GW GK+C      +L  +E    C+      C+G G C  GKC+C     
Sbjct: 294  CNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGD 353

Query: 962  RGYKGKFCGEID--CPH---PTCSGHGFCIEGTCVCKKGWKGADCG-----TMDKDALQC 1011
            R   GK C   D  C       C GHG C  G CVC++GW G  C       M ++  + 
Sbjct: 354  RRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQHPRKCNMTEEQSKN 413

Query: 1012 LPD------CSGHGTFDVDTQTCSCHAKW--SGE--DCSKEVCS----LECGPHGRCVGE 1057
            L +      CSG G+       CS   +W  SGE  DC    C     L C  +G C   
Sbjct: 414  LCESADGILCSGKGSCHCGKCICSAE-EWYISGEFCDCDDRDCDKHDGLICTGNGICSCG 472

Query: 1058 SCSCAAGWSGEFCSVRL 1074
            +C C  GW+G  C + L
Sbjct: 473  NCECWDGWNGNACEIWL 489


>AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.
          Length = 1282

 Score =  103 bits (247), Expect = 1e-20
 Identities = 92/346 (26%), Positives = 127/346 (36%), Gaps = 50/346 (14%)

Query: 882  CSGKGECLMG----HCQCQPGFGGDDC--SKSVCPVLCSQRG---EYINGE--CQCNPGW 930
            C   G C  G     CQC  GFGG  C  ++S C     Q G   +  NG   C C  G+
Sbjct: 189  CQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 248

Query: 931  KGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEIDCPHP------TCS 980
             G  C +  D+C    C   G CV    N  C C   +KG  C   D P P       C 
Sbjct: 249  TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCH 308

Query: 981  GHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSG 1036
              G C++      C C +G+ G DC     D  +C    +G      +T  C C   + G
Sbjct: 309  NGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECR---NGGRCLGANTTLCQCPLGFFG 365

Query: 1037 EDCSKEVCSLECGPHGRCV--------GES--CSCAAGWSGEFCSVRLCDA-RCAEHGQC 1085
              C  E+ ++ C  + +C         G S  C C    +        CD+  C   G C
Sbjct: 366  LLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSC 425

Query: 1086 ----KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCR-----VDNDGRWECKCFDGWDGPD 1136
                 + TC C  G++G+HC  +  P  C+  G CR      +  G + C C   + G  
Sbjct: 426  DAHDDSYTCECPRGFHGKHCE-KARPHLCSS-GPCRNGGTCKEAGGEYHCSCPYRFTGRH 483

Query: 1137 CTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSPKP 1182
            C   K   C     ++            C  P   S + C  +P P
Sbjct: 484  CEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSP 529



 Score = 89.8 bits (213), Expect = 1e-16
 Identities = 86/295 (29%), Positives = 114/295 (38%), Gaps = 41/295 (13%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHP 977
            C C  G+ G+ C L  +EC    C   G C +G    +C C  G+ G  C   +  C   
Sbjct: 166  CSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTK 225

Query: 978  TCSGHGFC-IE---GTCVCKKGWKGADCGTMDKDALQCLPD-C-SGHGTFD-VDTQTCSC 1030
             C   G C +E     CVC+ G+ GA C  MD D   C PD C +G    D V   TC C
Sbjct: 226  ECQHGGQCQVENGSAVCVCQAGYTGAAC-EMDVD--DCSPDPCLNGGSCVDLVGNYTCLC 282

Query: 1031 HAKWSGEDCS------KEVC-SLECGPHGRCV----GESCSCAAGWSGEFCSVRL-CDAR 1078
               + G  C        + C S  C   G CV    G  C C  G+ G  C  R+  D  
Sbjct: 283  AEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE 342

Query: 1079 CAEHGQC--KNGT-CLCVSGWNGRHCTLEGCPRSCAGHGQCR-----VDNDGRWECKCFD 1130
            C   G+C   N T C C  G+ G  C  E     C  + QC      +++ G + C C  
Sbjct: 343  CRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHT 402

Query: 1131 GWDGPDC--TTLKEQICDDSRDND-KDGLVDCEDPECCQSPACKSSQ--LCVSSP 1180
              +      +      C +    D  D    CE P       C+ ++  LC S P
Sbjct: 403  DHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGP 457



 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 78/295 (26%), Positives = 104/295 (35%), Gaps = 35/295 (11%)

Query: 876  HNCPNG-CSGKGECLMG----HCQCQPGFGGDDCS----KSVCPVLCSQRG---EYING- 922
            H C +G C   G C       HC C   F G  C      S     C   G    YI   
Sbjct: 451  HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKY 510

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFC-GEIDCPHP 977
            +C C PG+ G+ C +    C    C   G C +      C C  GY G+ C  E+DC  P
Sbjct: 511  KCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPP 570

Query: 978  TCSGHG-FCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSG 1036
                H      GT +        D G     A   +  C  HG +    Q          
Sbjct: 571  EEVKHATLRFNGTRLGAVALYACDRG-YSLSAPSRIRVCQPHGVWSEPPQCLEI------ 623

Query: 1037 EDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDAR---CAEHGQCKN----GT 1089
            ++C  + C        R  G  C C+ G+ G  C +   + R   C   G C+N      
Sbjct: 624  DECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYV 683

Query: 1090 CLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
            C C +G+ G HC  E   C  S   HG       G + C C + + G  C T+ +
Sbjct: 684  CRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSD 738



 Score = 76.2 bits (179), Expect = 2e-12
 Identities = 53/177 (29%), Positives = 73/177 (41%), Gaps = 23/177 (12%)

Query: 879  PNGC-SGKGECL-MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            P+G  S   +CL +  C+ QP   G  C   V   LC            C+ G++G  C 
Sbjct: 610  PHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCL-----------CSTGYEGAHCE 658

Query: 937  LRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFC-GEID-CPHPTCSGHGFCIEG-- 988
            L  DEC    C   G C N  G   C C  G+ G  C  E+D C    C   G C  G  
Sbjct: 659  LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 718

Query: 989  --TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV 1043
               CVC + + G  C T+            G+      + +C+C   ++GEDC+KE+
Sbjct: 719  AYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 775



 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 52/170 (30%), Positives = 66/170 (38%), Gaps = 21/170 (12%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNGK-CSCVRGYKGKFCG--EIDCPHP 977
            CQ +  W      L  DEC    C   G C   V G  C C  GY+G  C     +C   
Sbjct: 608  CQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAH 667

Query: 978  TCSGHGFC--IEGT--CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD--TQTCSCH 1031
             C   G C  + G   C C  G+ G  C T + DA    P C   G  +       C C 
Sbjct: 668  PCRNGGSCRNLPGAYVCRCPAGFVGVHCET-EVDACDSSP-CQHGGRCESGGGAYLCVCP 725

Query: 1032 AKWSGEDCS--KEVC-SLECGPHGRCVGE----SCSCAAGWSGEFCSVRL 1074
              + G  C    + C S  CG  G C+      SC+C  G++GE C+  L
Sbjct: 726  ESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 775



 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 61/236 (25%), Positives = 87/236 (36%), Gaps = 22/236 (9%)

Query: 924  CQCNPGWKGKECS-LRHDECEVPDCNGHGHC--VNGK--CSCVRGYKGKFC--GEID-CP 975
            C+C  G+ GK C   R   C    C   G C    G+  CSC   + G+ C  G+ D C 
Sbjct: 434  CECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCA 493

Query: 976  HPTCSGHGFCI----EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-CSC 1030
               C   G C     +  C C  G+ G  C        +  P  +G    D DT   C C
Sbjct: 494  SGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRS-PCVNGGTCEDRDTDFFCHC 552

Query: 1031 HAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTC 1090
             A + G  C  EV   +CGP    V  +     G      ++  CD   +     +   C
Sbjct: 553  QAGYMGRRCQAEV---DCGPPEE-VKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVC 608

Query: 1091 LCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQ 1143
                 W+     LE   C  + C   G C+ D    + C C  G++G  C   +++
Sbjct: 609  QPHGVWSEPPQCLEIDECRSQPCLHGGSCQ-DRVAGYLCLCSTGYEGAHCELERDE 663



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 13/94 (13%)

Query: 1064 GWSGEFCSVRLCDARCAEHGQCKNG--------TCLCVSGWNGRHCTL---EGCPRSCAG 1112
            G  G   SV L    C   G+C +         TC C+SG+ GR C L   E   + C  
Sbjct: 132  GGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQN 191

Query: 1113 HGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICD 1146
             G C       + C+C  G+ GP C T +   CD
Sbjct: 192  GGTC-THGINSFRCQCPAGFGGPTCETAQSP-CD 223



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 5/51 (9%)

Query: 865 SFVALVAEEMTHNC-PNGCSGKGECLMGH----CQCQPGFGGDDCSKSVCP 910
           SF     E ++  C  + C G+G CL  +    C C+ G+ G+DC+K + P
Sbjct: 727 SFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 777


>D86864-1|BAA24070.1|  830|Homo sapiens acetyl LDL receptor protein.
          Length = 830

 Score =  103 bits (246), Expect = 1e-20
 Identities = 93/302 (30%), Positives = 123/302 (40%), Gaps = 66/302 (21%)

Query: 879  PNGCSGKGECLM-GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGEC----------QCN 927
            P+ C     C+  G C+C+PGF G  CS S CP      G+Y   +C          QC 
Sbjct: 60   PDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCP------GQYWGPDCRESCPCHPHGQCE 112

Query: 928  PGWKGKECSLRH--DECEVP-DCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHPTCSGH 982
            P     +C        CE P  C  HG C    G C C  G+    C    C   T +  
Sbjct: 113  PATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
                 G CVCK GW G  C      + +C  +C G    + D+  C+C   W G +C ++
Sbjct: 172  CEQATGACVCKPGWWGRRC------SFRC--NCHG-SPCEQDSGRCACRPGWWGPECQQQ 222

Query: 1043 VCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDA-----RCAEH-GQCKN------- 1087
             C  EC   GRC   S  C+C  G+ G  C +  C A     +CA   G+CK+       
Sbjct: 223  -C--EC-VRGRCSAASGECTCPPGFRGARCELP-CPAGSHGVQCAHSCGRCKHNEPCSPD 277

Query: 1088 -GTC-LCVSGWNGRHCTL--------EGCPRSC--AGHGQCRVDNDGRWECKCFDGWDGP 1135
             G+C  C  GWNG  C          E C + C    HG+    + G  + +C  GW GP
Sbjct: 278  TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQ-RCDPGWLGP 336

Query: 1136 DC 1137
             C
Sbjct: 337  RC 338



 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 86/294 (29%), Positives = 113/294 (38%), Gaps = 63/294 (21%)

Query: 879  PNGCSGKGEC--LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            P  C   G C    G C C+PG+    C +       + R E   G C C PGW G+ CS
Sbjct: 132  PCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191

Query: 937  LRHDECEVPDCNGHGH-CV--NGKCSCVRGYKGKFC-GEIDCPHPTCSGHGFCIEGTCVC 992
             R        CN HG  C   +G+C+C  G+ G  C  + +C    CS       G C C
Sbjct: 192  FR--------CNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCS----AASGECTC 239

Query: 993  KKGWKGADCG---TMDKDALQCLPD---CSGHGTFDVDTQTC-SCHAKWSGEDCSK---- 1041
              G++GA C          +QC      C  +     DT +C SC   W+G  C +    
Sbjct: 240  PPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLP 299

Query: 1042 ----EVCSLECGPHGRCVGESCS--------CAAGWSGEFCSVRL--------CDARC-- 1079
                E C  +C PH R  GE+C         C  GW G  C            C + C  
Sbjct: 300  GTFGESCEQQC-PHCR-HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPT 357

Query: 1080 AEHGQCK--NGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDG 1131
               G C    G C+C +G+ G  C    CP    G+  C V       C+C +G
Sbjct: 358  CVQGSCDTVTGDCVCSAGYWGPSCN-ASCPAGFHGN-NCSV------PCECPEG 403



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 78/257 (30%), Positives = 101/257 (39%), Gaps = 49/257 (19%)

Query: 921  NGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPT 978
            + E QC  GW+ K+       CE PD C     CV  G C C  G+ G  C         
Sbjct: 36   SAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSS------R 89

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
            C G            + W G DC    +++  C P    HG  +  T  C C A   G  
Sbjct: 90   CPG------------QYW-GPDC----RESCPCHP----HGQCEPATGACQCQADRWGAR 128

Query: 1039 CSKEVCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDARCAEHGQCK--NGTCLCVS 1094
            C +  C+  CGPHGRC   +  C C  GW    C  R C    A   +C+   G C+C  
Sbjct: 129  C-EFPCA--CGPHGRCDPATGVCHCEPGWWSSTCR-RPCQCNTAA-ARCEQATGACVCKP 183

Query: 1095 GWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKD 1154
            GW GR C+       C  HG     + GR  C C  GW GP+C    +Q C+  R     
Sbjct: 184  GWWGRRCSFR-----CNCHGSPCEQDSGR--CACRPGWWGPEC----QQQCECVRGRCSA 232

Query: 1155 GLVDCEDPECCQSPACK 1171
               +C  P   +   C+
Sbjct: 233  ASGECTCPPGFRGARCE 249



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 3/58 (5%)

Query: 872 EEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPG 929
           E+    CP    G  + + G C C  G+ G  C+ S CP      G   +  C+C  G
Sbjct: 349 EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNAS-CP--AGFHGNNCSVPCECPEG 403


>D63483-1|BAA09770.1|  830|Homo sapiens KIAA0149 protein.
          Length = 830

 Score =  103 bits (246), Expect = 1e-20
 Identities = 93/302 (30%), Positives = 123/302 (40%), Gaps = 66/302 (21%)

Query: 879  PNGCSGKGECLM-GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGEC----------QCN 927
            P+ C     C+  G C+C+PGF G  CS S CP      G+Y   +C          QC 
Sbjct: 60   PDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCP------GQYWGPDCRESCPCHPHGQCE 112

Query: 928  PGWKGKECSLRH--DECEVP-DCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHPTCSGH 982
            P     +C        CE P  C  HG C    G C C  G+    C    C   T +  
Sbjct: 113  PATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
                 G CVCK GW G  C      + +C  +C G    + D+  C+C   W G +C ++
Sbjct: 172  CEQATGACVCKPGWWGRRC------SFRC--NCHG-SPCEQDSGRCACRPGWWGPECQQQ 222

Query: 1043 VCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDA-----RCAEH-GQCKN------- 1087
             C  EC   GRC   S  C+C  G+ G  C +  C A     +CA   G+CK+       
Sbjct: 223  -C--EC-VRGRCSAASGECTCPPGFRGARCELP-CPAGSHGVQCAHSCGRCKHNEPCSPD 277

Query: 1088 -GTC-LCVSGWNGRHCTL--------EGCPRSC--AGHGQCRVDNDGRWECKCFDGWDGP 1135
             G+C  C  GWNG  C          E C + C    HG+    + G  + +C  GW GP
Sbjct: 278  TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQ-RCDPGWLGP 336

Query: 1136 DC 1137
             C
Sbjct: 337  RC 338



 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 86/294 (29%), Positives = 113/294 (38%), Gaps = 63/294 (21%)

Query: 879  PNGCSGKGEC--LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            P  C   G C    G C C+PG+    C +       + R E   G C C PGW G+ CS
Sbjct: 132  PCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191

Query: 937  LRHDECEVPDCNGHGH-CV--NGKCSCVRGYKGKFC-GEIDCPHPTCSGHGFCIEGTCVC 992
             R        CN HG  C   +G+C+C  G+ G  C  + +C    CS       G C C
Sbjct: 192  FR--------CNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCS----AASGECTC 239

Query: 993  KKGWKGADCG---TMDKDALQCLPD---CSGHGTFDVDTQTC-SCHAKWSGEDCSK---- 1041
              G++GA C          +QC      C  +     DT +C SC   W+G  C +    
Sbjct: 240  PPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLP 299

Query: 1042 ----EVCSLECGPHGRCVGESCS--------CAAGWSGEFCSVRL--------CDARC-- 1079
                E C  +C PH R  GE+C         C  GW G  C            C + C  
Sbjct: 300  GTFGESCEQQC-PHCR-HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPT 357

Query: 1080 AEHGQCK--NGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDG 1131
               G C    G C+C +G+ G  C    CP    G+  C V       C+C +G
Sbjct: 358  CVQGSCDTVTGDCVCSAGYWGPSCN-ASCPAGFHGN-NCSV------PCECPEG 403



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 78/257 (30%), Positives = 101/257 (39%), Gaps = 49/257 (19%)

Query: 921  NGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPT 978
            + E QC  GW+ K+       CE PD C     CV  G C C  G+ G  C         
Sbjct: 36   SAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSS------R 89

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
            C G            + W G DC    +++  C P    HG  +  T  C C A   G  
Sbjct: 90   CPG------------QYW-GPDC----RESCPCHP----HGQCEPATGACQCQADRWGAR 128

Query: 1039 CSKEVCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDARCAEHGQCK--NGTCLCVS 1094
            C +  C+  CGPHGRC   +  C C  GW    C  R C    A   +C+   G C+C  
Sbjct: 129  C-EFPCA--CGPHGRCDPATGVCHCEPGWWSSTCR-RPCQCNTAA-ARCEQATGACVCKP 183

Query: 1095 GWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKD 1154
            GW GR C+       C  HG     + GR  C C  GW GP+C    +Q C+  R     
Sbjct: 184  GWWGRRCSFR-----CNCHGSPCEQDSGR--CACRPGWWGPEC----QQQCECVRGRCSA 232

Query: 1155 GLVDCEDPECCQSPACK 1171
               +C  P   +   C+
Sbjct: 233  ASGECTCPPGFRGARCE 249



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 3/58 (5%)

Query: 872 EEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPG 929
           E+    CP    G  + + G C C  G+ G  C+ S CP      G   +  C+C  G
Sbjct: 349 EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNAS-CP--AGFHGNNCSVPCECPEG 403


>BC039735-1|AAH39735.1|  830|Homo sapiens scavenger receptor class F,
            member 1 protein.
          Length = 830

 Score =  103 bits (246), Expect = 1e-20
 Identities = 93/302 (30%), Positives = 123/302 (40%), Gaps = 66/302 (21%)

Query: 879  PNGCSGKGECLM-GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGEC----------QCN 927
            P+ C     C+  G C+C+PGF G  CS S CP      G+Y   +C          QC 
Sbjct: 60   PDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCP------GQYWGPDCRESCPCHPHGQCE 112

Query: 928  PGWKGKECSLRH--DECEVP-DCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHPTCSGH 982
            P     +C        CE P  C  HG C    G C C  G+    C    C   T +  
Sbjct: 113  PATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
                 G CVCK GW G  C      + +C  +C G    + D+  C+C   W G +C ++
Sbjct: 172  CEQATGACVCKPGWWGRRC------SFRC--NCHG-SPCEQDSGRCACRPGWWGPECQQQ 222

Query: 1043 VCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDA-----RCAEH-GQCKN------- 1087
             C  EC   GRC   S  C+C  G+ G  C +  C A     +CA   G+CK+       
Sbjct: 223  -C--EC-VRGRCSAASGECTCPPGFRGARCELP-CPAGSHGVQCAHSCGRCKHNEPCSPD 277

Query: 1088 -GTC-LCVSGWNGRHCTL--------EGCPRSC--AGHGQCRVDNDGRWECKCFDGWDGP 1135
             G+C  C  GWNG  C          E C + C    HG+    + G  + +C  GW GP
Sbjct: 278  TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQ-RCDPGWLGP 336

Query: 1136 DC 1137
             C
Sbjct: 337  RC 338



 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 86/294 (29%), Positives = 113/294 (38%), Gaps = 63/294 (21%)

Query: 879  PNGCSGKGEC--LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            P  C   G C    G C C+PG+    C +       + R E   G C C PGW G+ CS
Sbjct: 132  PCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191

Query: 937  LRHDECEVPDCNGHGH-CV--NGKCSCVRGYKGKFC-GEIDCPHPTCSGHGFCIEGTCVC 992
             R        CN HG  C   +G+C+C  G+ G  C  + +C    CS       G C C
Sbjct: 192  FR--------CNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCS----AASGECTC 239

Query: 993  KKGWKGADCG---TMDKDALQCLPD---CSGHGTFDVDTQTC-SCHAKWSGEDCSK---- 1041
              G++GA C          +QC      C  +     DT +C SC   W+G  C +    
Sbjct: 240  PPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLP 299

Query: 1042 ----EVCSLECGPHGRCVGESCS--------CAAGWSGEFCSVRL--------CDARC-- 1079
                E C  +C PH R  GE+C         C  GW G  C            C + C  
Sbjct: 300  GTFGESCEQQC-PHCR-HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPT 357

Query: 1080 AEHGQCK--NGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDG 1131
               G C    G C+C +G+ G  C    CP    G+  C V       C+C +G
Sbjct: 358  CVQGSCDTVTGDCVCSAGYWGPSCN-ASCPAGFHGN-NCSV------PCECPEG 403



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 78/257 (30%), Positives = 101/257 (39%), Gaps = 49/257 (19%)

Query: 921  NGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPT 978
            + E QC  GW+ K+       CE PD C     CV  G C C  G+ G  C         
Sbjct: 36   SAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSS------R 89

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
            C G            + W G DC    +++  C P    HG  +  T  C C A   G  
Sbjct: 90   CPG------------QYW-GPDC----RESCPCHP----HGQCEPATGACQCQADRWGAR 128

Query: 1039 CSKEVCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDARCAEHGQCK--NGTCLCVS 1094
            C +  C+  CGPHGRC   +  C C  GW    C  R C    A   +C+   G C+C  
Sbjct: 129  C-EFPCA--CGPHGRCDPATGVCHCEPGWWSSTCR-RPCQCNTAA-ARCEQATGACVCKP 183

Query: 1095 GWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKD 1154
            GW GR C+       C  HG     + GR  C C  GW GP+C    +Q C+  R     
Sbjct: 184  GWWGRRCSFR-----CNCHGSPCEQDSGR--CACRPGWWGPEC----QQQCECVRGRCSA 232

Query: 1155 GLVDCEDPECCQSPACK 1171
               +C  P   +   C+
Sbjct: 233  ASGECTCPPGFRGARCE 249



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 3/58 (5%)

Query: 872 EEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPG 929
           E+    CP    G  + + G C C  G+ G  C+ S CP      G   +  C+C  G
Sbjct: 349 EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNAS-CP--AGFHGNNCSVPCECPEG 403


>AB052948-1|BAC02694.1|  569|Homo sapiens SREC-3 protein.
          Length = 569

 Score =  103 bits (246), Expect = 1e-20
 Identities = 93/302 (30%), Positives = 123/302 (40%), Gaps = 66/302 (21%)

Query: 879  PNGCSGKGECLM-GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGEC----------QCN 927
            P+ C     C+  G C+C+PGF G  CS S CP      G+Y   +C          QC 
Sbjct: 60   PDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCP------GQYWGPDCRESCPCHPHGQCE 112

Query: 928  PGWKGKECSLRH--DECEVP-DCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHPTCSGH 982
            P     +C        CE P  C  HG C    G C C  G+    C    C   T +  
Sbjct: 113  PATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
                 G CVCK GW G  C      + +C  +C G    + D+  C+C   W G +C ++
Sbjct: 172  CEQATGACVCKPGWWGRRC------SFRC--NCHG-SPCEQDSGRCACRPGWWGPECQQQ 222

Query: 1043 VCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDA-----RCAEH-GQCKN------- 1087
             C  EC   GRC   S  C+C  G+ G  C +  C A     +CA   G+CK+       
Sbjct: 223  -C--EC-VRGRCSAASGECTCPPGFRGARCELP-CPAGSHGVQCAHSCGRCKHNEPCSPD 277

Query: 1088 -GTC-LCVSGWNGRHCTL--------EGCPRSC--AGHGQCRVDNDGRWECKCFDGWDGP 1135
             G+C  C  GWNG  C          E C + C    HG+    + G  + +C  GW GP
Sbjct: 278  TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQ-RCDPGWLGP 336

Query: 1136 DC 1137
             C
Sbjct: 337  RC 338



 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 86/294 (29%), Positives = 113/294 (38%), Gaps = 63/294 (21%)

Query: 879  PNGCSGKGEC--LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            P  C   G C    G C C+PG+    C +       + R E   G C C PGW G+ CS
Sbjct: 132  PCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191

Query: 937  LRHDECEVPDCNGHGH-CV--NGKCSCVRGYKGKFC-GEIDCPHPTCSGHGFCIEGTCVC 992
             R        CN HG  C   +G+C+C  G+ G  C  + +C    CS       G C C
Sbjct: 192  FR--------CNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCS----AASGECTC 239

Query: 993  KKGWKGADCG---TMDKDALQCLPD---CSGHGTFDVDTQTC-SCHAKWSGEDCSK---- 1041
              G++GA C          +QC      C  +     DT +C SC   W+G  C +    
Sbjct: 240  PPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLP 299

Query: 1042 ----EVCSLECGPHGRCVGESCS--------CAAGWSGEFCSVRL--------CDARC-- 1079
                E C  +C PH R  GE+C         C  GW G  C            C + C  
Sbjct: 300  GTFGESCEQQC-PHCR-HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPT 357

Query: 1080 AEHGQCK--NGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDG 1131
               G C    G C+C +G+ G  C    CP    G+  C V       C+C +G
Sbjct: 358  CVQGSCDTVTGDCVCSAGYWGPSCN-ASCPAGFHGN-NCSV------PCECPEG 403



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 78/257 (30%), Positives = 101/257 (39%), Gaps = 49/257 (19%)

Query: 921  NGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPT 978
            + E QC  GW+ K+       CE PD C     CV  G C C  G+ G  C         
Sbjct: 36   SAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSS------R 89

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
            C G            + W G DC    +++  C P    HG  +  T  C C A   G  
Sbjct: 90   CPG------------QYW-GPDC----RESCPCHP----HGQCEPATGACQCQADRWGAR 128

Query: 1039 CSKEVCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDARCAEHGQCK--NGTCLCVS 1094
            C +  C+  CGPHGRC   +  C C  GW    C  R C    A   +C+   G C+C  
Sbjct: 129  C-EFPCA--CGPHGRCDPATGVCHCEPGWWSSTCR-RPCQCNTAA-ARCEQATGACVCKP 183

Query: 1095 GWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKD 1154
            GW GR C+       C  HG     + GR  C C  GW GP+C    +Q C+  R     
Sbjct: 184  GWWGRRCSFR-----CNCHGSPCEQDSGR--CACRPGWWGPEC----QQQCECVRGRCSA 232

Query: 1155 GLVDCEDPECCQSPACK 1171
               +C  P   +   C+
Sbjct: 233  ASGECTCPPGFRGARCE 249



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 3/58 (5%)

Query: 872 EEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPG 929
           E+    CP    G  + + G C C  G+ G  C+ S CP      G   +  C+C  G
Sbjct: 349 EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNAS-CP--AGFHGNNCSVPCECPEG 403


>AB052946-1|BAC02692.1|  830|Homo sapiens SREC protein.
          Length = 830

 Score =  103 bits (246), Expect = 1e-20
 Identities = 93/302 (30%), Positives = 123/302 (40%), Gaps = 66/302 (21%)

Query: 879  PNGCSGKGECLM-GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGEC----------QCN 927
            P+ C     C+  G C+C+PGF G  CS S CP      G+Y   +C          QC 
Sbjct: 60   PDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCP------GQYWGPDCRESCPCHPHGQCE 112

Query: 928  PGWKGKECSLRH--DECEVP-DCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHPTCSGH 982
            P     +C        CE P  C  HG C    G C C  G+    C    C   T +  
Sbjct: 113  PATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
                 G CVCK GW G  C      + +C  +C G    + D+  C+C   W G +C ++
Sbjct: 172  CEQATGACVCKPGWWGRRC------SFRC--NCHG-SPCEQDSGRCACRPGWWGPECQQQ 222

Query: 1043 VCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDA-----RCAEH-GQCKN------- 1087
             C  EC   GRC   S  C+C  G+ G  C +  C A     +CA   G+CK+       
Sbjct: 223  -C--EC-VRGRCSAASGECTCPPGFRGARCELP-CPAGSHGVQCAHSCGRCKHNEPCSPD 277

Query: 1088 -GTC-LCVSGWNGRHCTL--------EGCPRSC--AGHGQCRVDNDGRWECKCFDGWDGP 1135
             G+C  C  GWNG  C          E C + C    HG+    + G  + +C  GW GP
Sbjct: 278  TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQ-RCDPGWLGP 336

Query: 1136 DC 1137
             C
Sbjct: 337  RC 338



 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 86/294 (29%), Positives = 113/294 (38%), Gaps = 63/294 (21%)

Query: 879  PNGCSGKGEC--LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            P  C   G C    G C C+PG+    C +       + R E   G C C PGW G+ CS
Sbjct: 132  PCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191

Query: 937  LRHDECEVPDCNGHGH-CV--NGKCSCVRGYKGKFC-GEIDCPHPTCSGHGFCIEGTCVC 992
             R        CN HG  C   +G+C+C  G+ G  C  + +C    CS       G C C
Sbjct: 192  FR--------CNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCS----AASGECTC 239

Query: 993  KKGWKGADCG---TMDKDALQCLPD---CSGHGTFDVDTQTC-SCHAKWSGEDCSK---- 1041
              G++GA C          +QC      C  +     DT +C SC   W+G  C +    
Sbjct: 240  PPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLP 299

Query: 1042 ----EVCSLECGPHGRCVGESCS--------CAAGWSGEFCSVRL--------CDARC-- 1079
                E C  +C PH R  GE+C         C  GW G  C            C + C  
Sbjct: 300  GTFGESCEQQC-PHCR-HGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPT 357

Query: 1080 AEHGQCK--NGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDG 1131
               G C    G C+C +G+ G  C    CP    G+  C V       C+C +G
Sbjct: 358  CVQGSCDTVTGDCVCSAGYWGPSCN-ASCPAGFHGN-NCSV------PCECPEG 403



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 78/257 (30%), Positives = 101/257 (39%), Gaps = 49/257 (19%)

Query: 921  NGECQCNPGWKGKECSLRHDECEVPD-CNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPT 978
            + E QC  GW+ K+       CE PD C     CV  G C C  G+ G  C         
Sbjct: 36   SAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSS------R 89

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
            C G            + W G DC    +++  C P    HG  +  T  C C A   G  
Sbjct: 90   CPG------------QYW-GPDC----RESCPCHP----HGQCEPATGACQCQADRWGAR 128

Query: 1039 CSKEVCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDARCAEHGQCK--NGTCLCVS 1094
            C +  C+  CGPHGRC   +  C C  GW    C  R C    A   +C+   G C+C  
Sbjct: 129  C-EFPCA--CGPHGRCDPATGVCHCEPGWWSSTCR-RPCQCNTAA-ARCEQATGACVCKP 183

Query: 1095 GWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKD 1154
            GW GR C+       C  HG     + GR  C C  GW GP+C    +Q C+  R     
Sbjct: 184  GWWGRRCSFR-----CNCHGSPCEQDSGR--CACRPGWWGPEC----QQQCECVRGRCSA 232

Query: 1155 GLVDCEDPECCQSPACK 1171
               +C  P   +   C+
Sbjct: 233  ASGECTCPPGFRGARCE 249



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 3/58 (5%)

Query: 872 EEMTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPG 929
           E+    CP    G  + + G C C  G+ G  C+ S CP      G   +  C+C  G
Sbjct: 349 EDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNAS-CP--AGFHGNNCSVPCECPEG 403


>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains 6
            protein.
          Length = 1229

 Score =  100 bits (239), Expect = 9e-20
 Identities = 98/335 (29%), Positives = 127/335 (37%), Gaps = 81/335 (24%)

Query: 878  CPNGCSGKGECLMGHC--QCQPGFGGDDCSKSVCPV---------LCSQRG---EYINGE 923
            CP G +   + + G C  +C  GF G+DC +  CPV          CS  G     + G+
Sbjct: 596  CPVGVAC--DSVSGECGKRCPAGFQGEDCGQE-CPVGTFGVNCSSSCSCGGAPCHGVTGQ 652

Query: 924  CQCNPGWKGKECSLRHDE------CE--VPDCNGHGHC--VNGKCSCVRGYKGKFCGEID 973
            C+C PG  G++C     E      C+   P C     C    G C C+ G+ G  C ++ 
Sbjct: 653  CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV- 711

Query: 974  CPH----PTCS--------GHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCS----- 1016
            CP     P+C         GH     G C C  GW G  C     D     PDCS     
Sbjct: 712  CPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRAC-DTGHWGPDCSHPCNC 770

Query: 1017 --GHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP---------HGRC---VGESCSCA 1062
              GHG+ D  +  C C A + G  C ++      GP         HG     V  +C+C 
Sbjct: 771  SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCP 830

Query: 1063 AGWSGEFCSVRLCDA-----------RCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPR- 1108
            AGW G FC    C A            C     C   NG+CLC +G  G  C  +  PR 
Sbjct: 831  AGWRGTFCE-HACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRD 889

Query: 1109 ---SCAGHGQC---RVDNDGRWECKCFDGWDGPDC 1137
                C   G C    + +     C C  GW G  C
Sbjct: 890  VRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKC 924



 Score = 89.0 bits (211), Expect = 2e-16
 Identities = 99/341 (29%), Positives = 125/341 (36%), Gaps = 89/341 (26%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP-----------VLCSQRG--EYINGE 923
            +C NG  G  + + G C+C PG  G +C    CP             C+ RG    + G 
Sbjct: 464  SCQNG--GTCDSVTGACRCPPGVSGTNCEDG-CPKGYYGKHCRKKCNCANRGRCHRLYGA 520

Query: 924  CQCNPGWKGKECSLRHDECEV-PDCNGHGHCV----------NGKCSCVRGYKGKFCG-- 970
            C C+PG  G+ C L        P C+    CV          +G CSC  G++G+ C   
Sbjct: 521  CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAE 580

Query: 971  -EIDCPHPTCSGHGFC--------IEGTC--VCKKGWKGADCG---TMDKDALQCLPDCS 1016
             E+    P C     C        + G C   C  G++G DCG    +    + C   CS
Sbjct: 581  CELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS 640

Query: 1017 -GHGTFDVDTQTCSCHAKWSGEDCS------------KEVC-----SLECGPH-GRC--- 1054
             G       T  C C    +GEDC             +E+C     +  C P  G C   
Sbjct: 641  CGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCL 700

Query: 1055 ---VGESCS--CAAGWSGEFCSVRLCDARCAEHGQC--KNGTCLCVSGWNGRHCTL---- 1103
               VG  C   C AGW G  C  R C   CA  G C    G C C  GW G  C      
Sbjct: 701  PGFVGSRCQDVCPAGWYGPSCQTR-CS--CANDGHCHPATGHCSCAPGWTGFSCQRACDT 757

Query: 1104 ----EGCPRSC---AGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                  C   C   AGHG C   +     C C  G+ GP C
Sbjct: 758  GHWGPDCSHPCNCSAGHGSCDAISG---LCLCEAGYVGPRC 795



 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 87/309 (28%), Positives = 112/309 (36%), Gaps = 68/309 (22%)

Query: 881  GCSGKGEC--LMGHCQCQPGFGGDDCSK--------SVCPVLCS----QRGEYINGECQC 926
            GC   G C    G C C  G+ GD C            C   CS        ++ G C+C
Sbjct: 899  GCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRC 958

Query: 927  NPGWKGKECSL-----RHDE-CE-VPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPH- 976
             PG+ G  C       R+   CE +  C   G C    G C C  G+ G  C  + CP  
Sbjct: 959  PPGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCN-LTCPQG 1017

Query: 977  ---PTCS-----GHGFC---IEGTCVCKKGWKGADCGT---MDKDALQCLPDCS--GHGT 1020
               P C+     G G     + GTC+C  G  G  C      ++  + C   CS    G 
Sbjct: 1018 RFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGL 1077

Query: 1021 FDVDTQTCSCHAKWSGEDCSKE--------VCSLECGPHGRCVGE----SCSCAAGWSGE 1068
                  +CSC   W+G  C            C LEC  H     E    +C C  G+ G+
Sbjct: 1078 CHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQ 1137

Query: 1069 FCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKC 1128
             C  R   A C  +  C+ G         G  CTL  C   C G   C   +    +C C
Sbjct: 1138 ACEHRRSGATC--NLDCRRGQF-------GPSCTLH-C--DCGGGADC---DPVSGQCHC 1182

Query: 1129 FDGWDGPDC 1137
             DG+ GP C
Sbjct: 1183 VDGYMGPTC 1191



 Score = 86.6 bits (205), Expect = 1e-15
 Identities = 91/320 (28%), Positives = 117/320 (36%), Gaps = 69/320 (21%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP G  G       H  C  GF G DC +S C        + +NG C C  G +G  C+ 
Sbjct: 829  CPAGWRGT---FCEHA-CPAGFFGLDC-RSACNCTAGAACDAVNGSCLCPAGRRGPRCAE 883

Query: 938  RHDECEV-PDCNGHGHCVNG--------KCSCVRGYKGKFC---------GEIDCPHPTC 979
            +    +V   C   G C+NG        +C C  G+ G  C         GE      +C
Sbjct: 884  KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSC 943

Query: 980  SGHGFC--IEGTCVCKKGWKGADC------GTMDKDALQCLPDCSGHGTFDVDTQTCSCH 1031
                 C  + G C C  G+ G+ C      G       Q L  C   G+ D  T  C C 
Sbjct: 944  PPGAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCEQ-LCGCLNGGSCDAATGACRCP 1002

Query: 1032 AKWSGEDCS------------KEVCSLECGPHGRC--VGESCSCAAGWSGEFCSVRL--- 1074
              + G DC+              VC   CG    C  V  +C C  G +G  C       
Sbjct: 1003 TGFLGTDCNLTCPQGRFGPNCTHVCG--CGQGAACDPVTGTCLCPPGRAGVRCERGCPQN 1060

Query: 1075 -----CDARCA--EHGQC--KNGTCLCVSGWNGRHCTLEGCP---RSCAGHGQCRVDNDG 1122
                 C+  C+    G C   NG+C C  GW GRHC L  CP      A H +C   N+ 
Sbjct: 1061 RFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCEL-ACPPGRYGAACHLECSCHNNS 1119

Query: 1123 RWE-----CKCFDGWDGPDC 1137
              E     C+C  G+ G  C
Sbjct: 1120 TCEPATGTCRCGPGFYGQAC 1139



 Score = 70.5 bits (165), Expect = 8e-11
 Identities = 95/337 (28%), Positives = 123/337 (36%), Gaps = 80/337 (23%)

Query: 866  FVALVAEEMTHNCP---NGCSGKGECLMG--HCQCQPGFGGDDCSKSV--------CPVL 912
            FV L  +   H+C    + C   G CL+G   C C  G+ G  C+++         C   
Sbjct: 404  FVCL-DDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFS 462

Query: 913  CS-QRG---EYINGECQCNPGWKGKECS------LRHDECEVP-DCNGHGHC--VNGKCS 959
            CS Q G   + + G C+C PG  G  C            C    +C   G C  + G C 
Sbjct: 463  CSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACL 522

Query: 960  CVRGYKGKFCGEIDCPH----PTCSGHGFCIE----------GTCVCKKGWKGADCGTMD 1005
            C  G  G+FC  + CP     P CS    C++          G+C CK G++G  C    
Sbjct: 523  CDPGLYGRFC-HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQA-- 579

Query: 1006 KDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCS--CAA 1063
                +C     G G +    Q C+C    + +  S E C   C P G   GE C   C  
Sbjct: 580  ----ECELGYFGPGCW----QACTCPVGVACDSVSGE-CGKRC-PAG-FQGEDCGQECPV 628

Query: 1064 GWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE--------GCPRSC-AGHG 1114
            G  G  CS          HG    G C C  G  G  C  +        GC   C A   
Sbjct: 629  GTFGVNCSSSCSCGGAPCHGV--TGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQH 686

Query: 1115 QCRVDND-GRWEC-------KCFD----GWDGPDCTT 1139
              R D + G   C       +C D    GW GP C T
Sbjct: 687  AARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQT 723



 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 52/189 (27%), Positives = 66/189 (34%), Gaps = 45/189 (23%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--------CPVLCSQRGEYI----NG 922
            TH C  G     + + G C C PG  G  C +          C   CS R   +    NG
Sbjct: 1024 THVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNG 1083

Query: 923  ECQCNPGWKGKECSLR----------HDECEVPDCNGHGHC--VNGKCSCVRGYKGKFCG 970
             C C  GW G+ C L           H EC    C+ +  C    G C C  G+ G+ C 
Sbjct: 1084 SCSCGLGWTGRHCELACPPGRYGAACHLEC---SCHNNSTCEPATGTCRCGPGFYGQAC- 1139

Query: 971  EIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSC 1030
            E      TC+           C++G  G  C       L C  DC G    D  +  C C
Sbjct: 1140 EHRRSGATCN---------LDCRRGQFGPSC------TLHC--DCGGGADCDPVSGQCHC 1182

Query: 1031 HAKWSGEDC 1039
               + G  C
Sbjct: 1183 VDGYMGPTC 1191



 Score = 47.6 bits (108), Expect = 7e-04
 Identities = 41/128 (32%), Positives = 51/128 (39%), Gaps = 30/128 (23%)

Query: 873  EMTHNCPNG--C-SGKGECLMG------HCQ--CQPGFGGDDCSKSVCPVLCSQRGEYIN 921
            E T +C NG  C +  G C  G      HC+  C PG  G  C    C    +   E   
Sbjct: 1067 EHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLE-CSCHNNSTCEPAT 1125

Query: 922  GECQCNPGWKGKECSLRHD--ECEVP--------------DCNGHGHC--VNGKCSCVRG 963
            G C+C PG+ G+ C  R     C +               DC G   C  V+G+C CV G
Sbjct: 1126 GTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDG 1185

Query: 964  YKGKFCGE 971
            Y G  C E
Sbjct: 1186 YMGPTCRE 1193



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 69/256 (26%), Positives = 95/256 (37%), Gaps = 45/256 (17%)

Query: 893  CQCQPGF----GGDDC-SKSVCP---VLCSQRGEYING--ECQCNPGWK----GKECSLR 938
            CQC+PGF     G  C  +S C      C  R + + G   C+C+ G++    GK C   
Sbjct: 122  CQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-D 180

Query: 939  HDECE--VPDCNGHGHCVNG----KCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVC 992
             DEC   +  C  HG C+N     KC C  GY      E+      C      I  +C  
Sbjct: 181  VDECAAGLAQC-AHG-CLNTQGSFKCVCHAGY------ELGADGRQCYRIEMEIVNSCEA 232

Query: 993  KKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG 1052
              G     C       L C   C      D D +TC      +   C ++VC+   G   
Sbjct: 233  NNGGCSHGCSHTSAGPL-C--TCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPG--- 286

Query: 1053 RCVGESCSCAAGW--SGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHC----TLEGC 1106
               G  C C AG+  S + C     D   +  G C++  C  ++G     C     L   
Sbjct: 287  ---GYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHED 342

Query: 1107 PRSCAGHGQCRVDNDG 1122
             R C+   +  VD DG
Sbjct: 343  RRGCSPLEEPMVDLDG 358



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 58/252 (23%), Positives = 91/252 (36%), Gaps = 42/252 (16%)

Query: 924  CQCNPGWK----GKECSLRHDECEVPDCNGHGHCVN-----GKCSCVRGYKGKFCGEIDC 974
            C+C PG++     + C L  + C + +     HCV       +C C  G++ +  G    
Sbjct: 80   CECKPGFRLHTDSRTC-LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 138

Query: 975  PHPTCSG-HGFCIE--------GTCVCKKGWKGADCGTMDKDALQC---LPDCSGHGTFD 1022
                C+  +G C+           C C  G++ A  G   +D  +C   L  C+ HG  +
Sbjct: 139  RRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCA-HGCLN 197

Query: 1023 VDTQ-TCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE 1081
                  C CHA +      ++   +E      C   +  C+ G S       LC      
Sbjct: 198  TQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGP-LCTCPRGY 256

Query: 1082 HGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGW----DGPDC 1137
                   TC+ V       C    C + C        +N G +EC C+ G+    DG  C
Sbjct: 257  ELDTDQRTCIDVDDCADSPC----CQQVCT-------NNPGGYECGCYAGYRLSADGCGC 305

Query: 1138 TTLKEQICDDSR 1149
              + E  C  SR
Sbjct: 306  EDVDE--CASSR 315


>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains 6
            protein.
          Length = 1229

 Score =  100 bits (239), Expect = 9e-20
 Identities = 98/335 (29%), Positives = 127/335 (37%), Gaps = 81/335 (24%)

Query: 878  CPNGCSGKGECLMGHC--QCQPGFGGDDCSKSVCPV---------LCSQRG---EYINGE 923
            CP G +   + + G C  +C  GF G+DC +  CPV          CS  G     + G+
Sbjct: 596  CPVGVAC--DSVSGECGKRCPAGFQGEDCGQE-CPVGTFGVNCSSSCSCGGAPCHGVTGQ 652

Query: 924  CQCNPGWKGKECSLRHDE------CE--VPDCNGHGHC--VNGKCSCVRGYKGKFCGEID 973
            C+C PG  G++C     E      C+   P C     C    G C C+ G+ G  C ++ 
Sbjct: 653  CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV- 711

Query: 974  CPH----PTCS--------GHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCS----- 1016
            CP     P+C         GH     G C C  GW G  C     D     PDCS     
Sbjct: 712  CPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRAC-DTGHWGPDCSHPCNC 770

Query: 1017 --GHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP---------HGRC---VGESCSCA 1062
              GHG+ D  +  C C A + G  C ++      GP         HG     V  +C+C 
Sbjct: 771  SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCP 830

Query: 1063 AGWSGEFCSVRLCDA-----------RCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPR- 1108
            AGW G FC    C A            C     C   NG+CLC +G  G  C  +  PR 
Sbjct: 831  AGWRGTFCE-HACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRD 889

Query: 1109 ---SCAGHGQC---RVDNDGRWECKCFDGWDGPDC 1137
                C   G C    + +     C C  GW G  C
Sbjct: 890  VRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKC 924



 Score = 89.0 bits (211), Expect = 2e-16
 Identities = 99/341 (29%), Positives = 125/341 (36%), Gaps = 89/341 (26%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP-----------VLCSQRG--EYINGE 923
            +C NG  G  + + G C+C PG  G +C    CP             C+ RG    + G 
Sbjct: 464  SCQNG--GTCDSVTGACRCPPGVSGTNCEDG-CPKGYYGKHCRKKCNCANRGRCHRLYGA 520

Query: 924  CQCNPGWKGKECSLRHDECEV-PDCNGHGHCV----------NGKCSCVRGYKGKFCG-- 970
            C C+PG  G+ C L        P C+    CV          +G CSC  G++G+ C   
Sbjct: 521  CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAE 580

Query: 971  -EIDCPHPTCSGHGFC--------IEGTC--VCKKGWKGADCG---TMDKDALQCLPDCS 1016
             E+    P C     C        + G C   C  G++G DCG    +    + C   CS
Sbjct: 581  CELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS 640

Query: 1017 -GHGTFDVDTQTCSCHAKWSGEDCS------------KEVC-----SLECGPH-GRC--- 1054
             G       T  C C    +GEDC             +E+C     +  C P  G C   
Sbjct: 641  CGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCL 700

Query: 1055 ---VGESCS--CAAGWSGEFCSVRLCDARCAEHGQC--KNGTCLCVSGWNGRHCTL---- 1103
               VG  C   C AGW G  C  R C   CA  G C    G C C  GW G  C      
Sbjct: 701  PGFVGSRCQDVCPAGWYGPSCQTR-CS--CANDGHCHPATGHCSCAPGWTGFSCQRACDT 757

Query: 1104 ----EGCPRSC---AGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                  C   C   AGHG C   +     C C  G+ GP C
Sbjct: 758  GHWGPDCSHPCNCSAGHGSCDAISG---LCLCEAGYVGPRC 795



 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 87/309 (28%), Positives = 112/309 (36%), Gaps = 68/309 (22%)

Query: 881  GCSGKGEC--LMGHCQCQPGFGGDDCSK--------SVCPVLCS----QRGEYINGECQC 926
            GC   G C    G C C  G+ GD C            C   CS        ++ G C+C
Sbjct: 899  GCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRC 958

Query: 927  NPGWKGKECSL-----RHDE-CE-VPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPH- 976
             PG+ G  C       R+   CE +  C   G C    G C C  G+ G  C  + CP  
Sbjct: 959  PPGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCN-LTCPQG 1017

Query: 977  ---PTCS-----GHGFC---IEGTCVCKKGWKGADCGT---MDKDALQCLPDCS--GHGT 1020
               P C+     G G     + GTC+C  G  G  C      ++  + C   CS    G 
Sbjct: 1018 RFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGL 1077

Query: 1021 FDVDTQTCSCHAKWSGEDCSKE--------VCSLECGPHGRCVGE----SCSCAAGWSGE 1068
                  +CSC   W+G  C            C LEC  H     E    +C C  G+ G+
Sbjct: 1078 CHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQ 1137

Query: 1069 FCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKC 1128
             C  R   A C  +  C+ G         G  CTL  C   C G   C   +    +C C
Sbjct: 1138 ACEHRRSGATC--NLDCRRGQF-------GPSCTLH-C--DCGGGADC---DPVSGQCHC 1182

Query: 1129 FDGWDGPDC 1137
             DG+ GP C
Sbjct: 1183 VDGYMGPTC 1191



 Score = 86.6 bits (205), Expect = 1e-15
 Identities = 91/320 (28%), Positives = 117/320 (36%), Gaps = 69/320 (21%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP G  G       H  C  GF G DC +S C        + +NG C C  G +G  C+ 
Sbjct: 829  CPAGWRGT---FCEHA-CPAGFFGLDC-RSACNCTAGAACDAVNGSCLCPAGRRGPRCAE 883

Query: 938  RHDECEV-PDCNGHGHCVNG--------KCSCVRGYKGKFC---------GEIDCPHPTC 979
            +    +V   C   G C+NG        +C C  G+ G  C         GE      +C
Sbjct: 884  KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSC 943

Query: 980  SGHGFC--IEGTCVCKKGWKGADC------GTMDKDALQCLPDCSGHGTFDVDTQTCSCH 1031
                 C  + G C C  G+ G+ C      G       Q L  C   G+ D  T  C C 
Sbjct: 944  PPGAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCEQ-LCGCLNGGSCDAATGACRCP 1002

Query: 1032 AKWSGEDCS------------KEVCSLECGPHGRC--VGESCSCAAGWSGEFCSVRL--- 1074
              + G DC+              VC   CG    C  V  +C C  G +G  C       
Sbjct: 1003 TGFLGTDCNLTCPQGRFGPNCTHVCG--CGQGAACDPVTGTCLCPPGRAGVRCERGCPQN 1060

Query: 1075 -----CDARCA--EHGQC--KNGTCLCVSGWNGRHCTLEGCP---RSCAGHGQCRVDNDG 1122
                 C+  C+    G C   NG+C C  GW GRHC L  CP      A H +C   N+ 
Sbjct: 1061 RFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCEL-ACPPGRYGAACHLECSCHNNS 1119

Query: 1123 RWE-----CKCFDGWDGPDC 1137
              E     C+C  G+ G  C
Sbjct: 1120 TCEPATGTCRCGPGFYGQAC 1139



 Score = 70.5 bits (165), Expect = 8e-11
 Identities = 95/337 (28%), Positives = 123/337 (36%), Gaps = 80/337 (23%)

Query: 866  FVALVAEEMTHNCP---NGCSGKGECLMG--HCQCQPGFGGDDCSKSV--------CPVL 912
            FV L  +   H+C    + C   G CL+G   C C  G+ G  C+++         C   
Sbjct: 404  FVCL-DDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFS 462

Query: 913  CS-QRG---EYINGECQCNPGWKGKECS------LRHDECEVP-DCNGHGHC--VNGKCS 959
            CS Q G   + + G C+C PG  G  C            C    +C   G C  + G C 
Sbjct: 463  CSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACL 522

Query: 960  CVRGYKGKFCGEIDCPH----PTCSGHGFCIE----------GTCVCKKGWKGADCGTMD 1005
            C  G  G+FC  + CP     P CS    C++          G+C CK G++G  C    
Sbjct: 523  CDPGLYGRFC-HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQA-- 579

Query: 1006 KDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCS--CAA 1063
                +C     G G +    Q C+C    + +  S E C   C P G   GE C   C  
Sbjct: 580  ----ECELGYFGPGCW----QACTCPVGVACDSVSGE-CGKRC-PAG-FQGEDCGQECPV 628

Query: 1064 GWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE--------GCPRSC-AGHG 1114
            G  G  CS          HG    G C C  G  G  C  +        GC   C A   
Sbjct: 629  GTFGVNCSSSCSCGGAPCHGV--TGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQH 686

Query: 1115 QCRVDND-GRWEC-------KCFD----GWDGPDCTT 1139
              R D + G   C       +C D    GW GP C T
Sbjct: 687  AARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQT 723



 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 52/189 (27%), Positives = 66/189 (34%), Gaps = 45/189 (23%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--------CPVLCSQRGEYI----NG 922
            TH C  G     + + G C C PG  G  C +          C   CS R   +    NG
Sbjct: 1024 THVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNG 1083

Query: 923  ECQCNPGWKGKECSLR----------HDECEVPDCNGHGHC--VNGKCSCVRGYKGKFCG 970
             C C  GW G+ C L           H EC    C+ +  C    G C C  G+ G+ C 
Sbjct: 1084 SCSCGLGWTGRHCELACPPGRYGAACHLEC---SCHNNSTCEPATGTCRCGPGFYGQAC- 1139

Query: 971  EIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSC 1030
            E      TC+           C++G  G  C       L C  DC G    D  +  C C
Sbjct: 1140 EHRRSGATCN---------LDCRRGQFGPSC------TLHC--DCGGGADCDPVSGQCHC 1182

Query: 1031 HAKWSGEDC 1039
               + G  C
Sbjct: 1183 VDGYMGPTC 1191



 Score = 47.6 bits (108), Expect = 7e-04
 Identities = 41/128 (32%), Positives = 51/128 (39%), Gaps = 30/128 (23%)

Query: 873  EMTHNCPNG--C-SGKGECLMG------HCQ--CQPGFGGDDCSKSVCPVLCSQRGEYIN 921
            E T +C NG  C +  G C  G      HC+  C PG  G  C    C    +   E   
Sbjct: 1067 EHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLE-CSCHNNSTCEPAT 1125

Query: 922  GECQCNPGWKGKECSLRHD--ECEVP--------------DCNGHGHC--VNGKCSCVRG 963
            G C+C PG+ G+ C  R     C +               DC G   C  V+G+C CV G
Sbjct: 1126 GTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDG 1185

Query: 964  YKGKFCGE 971
            Y G  C E
Sbjct: 1186 YMGPTCRE 1193



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 69/256 (26%), Positives = 95/256 (37%), Gaps = 45/256 (17%)

Query: 893  CQCQPGF----GGDDC-SKSVCP---VLCSQRGEYING--ECQCNPGWK----GKECSLR 938
            CQC+PGF     G  C  +S C      C  R + + G   C+C+ G++    GK C   
Sbjct: 122  CQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-D 180

Query: 939  HDECE--VPDCNGHGHCVNG----KCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVC 992
             DEC   +  C  HG C+N     KC C  GY      E+      C      I  +C  
Sbjct: 181  VDECAAGLAQC-AHG-CLNTQGSFKCVCHAGY------ELGADGRQCYRIEMEIVNSCEA 232

Query: 993  KKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG 1052
              G     C       L C   C      D D +TC      +   C ++VC+   G   
Sbjct: 233  NNGGCSHGCSHTSAGPL-C--TCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPG--- 286

Query: 1053 RCVGESCSCAAGW--SGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHC----TLEGC 1106
               G  C C AG+  S + C     D   +  G C++  C  ++G     C     L   
Sbjct: 287  ---GYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHED 342

Query: 1107 PRSCAGHGQCRVDNDG 1122
             R C+   +  VD DG
Sbjct: 343  RRGCSPLEEPMVDLDG 358



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 58/252 (23%), Positives = 91/252 (36%), Gaps = 42/252 (16%)

Query: 924  CQCNPGWK----GKECSLRHDECEVPDCNGHGHCVN-----GKCSCVRGYKGKFCGEIDC 974
            C+C PG++     + C L  + C + +     HCV       +C C  G++ +  G    
Sbjct: 80   CECKPGFRLHTDSRTC-LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 138

Query: 975  PHPTCSG-HGFCIE--------GTCVCKKGWKGADCGTMDKDALQC---LPDCSGHGTFD 1022
                C+  +G C+           C C  G++ A  G   +D  +C   L  C+ HG  +
Sbjct: 139  RRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCA-HGCLN 197

Query: 1023 VDTQ-TCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE 1081
                  C CHA +      ++   +E      C   +  C+ G S       LC      
Sbjct: 198  TQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGP-LCTCPRGY 256

Query: 1082 HGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGW----DGPDC 1137
                   TC+ V       C    C + C        +N G +EC C+ G+    DG  C
Sbjct: 257  ELDTDQRTCIDVDDCADSPC----CQQVCT-------NNPGGYECGCYAGYRLSADGCGC 305

Query: 1138 TTLKEQICDDSR 1149
              + E  C  SR
Sbjct: 306  EDVDE--CASSR 315


>AB052949-1|BAC02695.1|  337|Homo sapiens SREC-4 protein.
          Length = 337

 Score =  100 bits (239), Expect = 9e-20
 Identities = 92/300 (30%), Positives = 122/300 (40%), Gaps = 66/300 (22%)

Query: 879  PNGCSGKGECLM-GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGEC----------QCN 927
            P+ C     C+  G C+C+PGF G  CS S CP      G+Y   +C          QC 
Sbjct: 60   PDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCP------GQYWGPDCRESCPCHPHGQCE 112

Query: 928  PGWKGKECSLRH--DECEVP-DCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHPTCSGH 982
            P     +C        CE P  C  HG C    G C C  G+    C    C   T +  
Sbjct: 113  PATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
                 G CVCK GW G  C      + +C  +C G    + D+  C+C   W G +C ++
Sbjct: 172  CEQATGACVCKPGWWGRRC------SFRC--NCHG-SPCEQDSGRCACRPGWWGPECQQQ 222

Query: 1043 VCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDA-----RCAEH-GQCKN------- 1087
             C  EC   GRC   S  C+C  G+ G  C +  C A     +CA   G+CK+       
Sbjct: 223  -C--EC-VRGRCSAASGECTCPPGFRGARCELP-CPAGSHGVQCAHSCGRCKHNEPCSPD 277

Query: 1088 -GTC-LCVSGWNGRHCTL--------EGCPRSC--AGHGQCRVDNDGRWECKCFDGWDGP 1135
             G+C  C  GWNG  C          E C + C    HG+    + G  + +C  GW GP
Sbjct: 278  TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQ-RCDPGWLGP 336



 Score = 91.9 bits (218), Expect = 3e-17
 Identities = 70/234 (29%), Positives = 94/234 (40%), Gaps = 37/234 (15%)

Query: 955  NGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-------GTCVCKKGWKGADCGTM--- 1004
            + +  C  G++ K   + +C  P C G   C +       G C CK G+ GA C +    
Sbjct: 36   SAELQCCAGWRQK---DQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPG 92

Query: 1005 ---DKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES--C 1059
                 D  +  P C  HG  +  T  C C A   G  C    C+  CGPHGRC   +  C
Sbjct: 93   QYWGPDCRESCP-CHPHGQCEPATGACQCQADRWGARCEFP-CA--CGPHGRCDPATGVC 148

Query: 1060 SCAAGWSGEFCSVRLCDARCAEHGQCKN--GTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C  GW    C  R C    A   +C+   G C+C  GW GR C+       C  HG   
Sbjct: 149  HCEPGWWSSTCR-RPCQCNTAA-ARCEQATGACVCKPGWWGRRCSFR-----CNCHGSPC 201

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACK 1171
              + GR  C C  GW GP+C    +Q C+  R        +C  P   +   C+
Sbjct: 202  EQDSGR--CACRPGWWGPEC----QQQCECVRGRCSAASGECTCPPGFRGARCE 249


>AB052947-1|BAC02693.1|  342|Homo sapiens SREC-2 protein.
          Length = 342

 Score =  100 bits (239), Expect = 9e-20
 Identities = 92/300 (30%), Positives = 122/300 (40%), Gaps = 66/300 (22%)

Query: 879  PNGCSGKGECLM-GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGEC----------QCN 927
            P+ C     C+  G C+C+PGF G  CS S CP      G+Y   +C          QC 
Sbjct: 60   PDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCP------GQYWGPDCRESCPCHPHGQCE 112

Query: 928  PGWKGKECSLRH--DECEVP-DCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHPTCSGH 982
            P     +C        CE P  C  HG C    G C C  G+    C    C   T +  
Sbjct: 113  PATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
                 G CVCK GW G  C      + +C  +C G    + D+  C+C   W G +C ++
Sbjct: 172  CEQATGACVCKPGWWGRRC------SFRC--NCHG-SPCEQDSGRCACRPGWWGPECQQQ 222

Query: 1043 VCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDA-----RCAEH-GQCKN------- 1087
             C  EC   GRC   S  C+C  G+ G  C +  C A     +CA   G+CK+       
Sbjct: 223  -C--EC-VRGRCSAASGECTCPPGFRGARCELP-CPAGSHGVQCAHSCGRCKHNEPCSPD 277

Query: 1088 -GTC-LCVSGWNGRHCTL--------EGCPRSC--AGHGQCRVDNDGRWECKCFDGWDGP 1135
             G+C  C  GWNG  C          E C + C    HG+    + G  + +C  GW GP
Sbjct: 278  TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQ-RCDPGWLGP 336



 Score = 91.9 bits (218), Expect = 3e-17
 Identities = 70/234 (29%), Positives = 94/234 (40%), Gaps = 37/234 (15%)

Query: 955  NGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-------GTCVCKKGWKGADCGTM--- 1004
            + +  C  G++ K   + +C  P C G   C +       G C CK G+ GA C +    
Sbjct: 36   SAELQCCAGWRQK---DQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPG 92

Query: 1005 ---DKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES--C 1059
                 D  +  P C  HG  +  T  C C A   G  C    C+  CGPHGRC   +  C
Sbjct: 93   QYWGPDCRESCP-CHPHGQCEPATGACQCQADRWGARCEFP-CA--CGPHGRCDPATGVC 148

Query: 1060 SCAAGWSGEFCSVRLCDARCAEHGQCKN--GTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C  GW    C  R C    A   +C+   G C+C  GW GR C+       C  HG   
Sbjct: 149  HCEPGWWSSTCR-RPCQCNTAA-ARCEQATGACVCKPGWWGRRCSFR-----CNCHGSPC 201

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACK 1171
              + GR  C C  GW GP+C    +Q C+  R        +C  P   +   C+
Sbjct: 202  EQDSGR--CACRPGWWGPEC----QQQCECVRGRCSAASGECTCPPGFRGARCE 249


>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
          Length = 1246

 Score =  100 bits (239), Expect = 9e-20
 Identities = 98/335 (29%), Positives = 127/335 (37%), Gaps = 81/335 (24%)

Query: 878  CPNGCSGKGECLMGHC--QCQPGFGGDDCSKSVCPV---------LCSQRG---EYINGE 923
            CP G +   + + G C  +C  GF G+DC +  CPV          CS  G     + G+
Sbjct: 613  CPVGVAC--DSVSGECGKRCPAGFQGEDCGQE-CPVGTFGVNCSSSCSCGGAPCHGVTGQ 669

Query: 924  CQCNPGWKGKECSLRHDE------CE--VPDCNGHGHC--VNGKCSCVRGYKGKFCGEID 973
            C+C PG  G++C     E      C+   P C     C    G C C+ G+ G  C ++ 
Sbjct: 670  CRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV- 728

Query: 974  CPH----PTCS--------GHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCS----- 1016
            CP     P+C         GH     G C C  GW G  C     D     PDCS     
Sbjct: 729  CPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRAC-DTGHWGPDCSHPCNC 787

Query: 1017 --GHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP---------HGRC---VGESCSCA 1062
              GHG+ D  +  C C A + G  C ++      GP         HG     V  +C+C 
Sbjct: 788  SAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQLCQCQHGAACDHVSGACTCP 847

Query: 1063 AGWSGEFCSVRLCDA-----------RCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPR- 1108
            AGW G FC    C A            C     C   NG+CLC +G  G  C  +  PR 
Sbjct: 848  AGWRGTFCE-HACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCLPRD 906

Query: 1109 ---SCAGHGQC---RVDNDGRWECKCFDGWDGPDC 1137
                C   G C    + +     C C  GW G  C
Sbjct: 907  VRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKC 941



 Score = 89.8 bits (213), Expect = 1e-16
 Identities = 108/377 (28%), Positives = 136/377 (36%), Gaps = 96/377 (25%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCP-----------VLCSQRG--EYINGE 923
            +C NG  G  + + G C+C PG  G +C    CP             C+ RG    + G 
Sbjct: 481  SCQNG--GTCDSVTGACRCPPGVSGTNCEDG-CPKGYYGKHCRKKCNCANRGRCHRLYGA 537

Query: 924  CQCNPGWKGKECSLRHDECEV-PDCNGHGHCV----------NGKCSCVRGYKGKFCG-- 970
            C C+PG  G+ C L        P C+    CV          +G CSC  G++G+ C   
Sbjct: 538  CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAE 597

Query: 971  -EIDCPHPTCSGHGFC--------IEGTC--VCKKGWKGADCG---TMDKDALQCLPDCS 1016
             E+    P C     C        + G C   C  G++G DCG    +    + C   CS
Sbjct: 598  CELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS 657

Query: 1017 -GHGTFDVDTQTCSCHAKWSGEDCS------------KEVC-----SLECGPH-GRC--- 1054
             G       T  C C    +GEDC             +E+C     +  C P  G C   
Sbjct: 658  CGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCL 717

Query: 1055 ---VGESCS--CAAGWSGEFCSVRLCDARCAEHGQC--KNGTCLCVSGWNGRHCTL---- 1103
               VG  C   C AGW G  C  R C   CA  G C    G C C  GW G  C      
Sbjct: 718  PGFVGSRCQDVCPAGWYGPSCQTR-CS--CANDGHCHPATGHCSCAPGWTGFSCQRACDT 774

Query: 1104 ----EGCPRSC---AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDK-DG 1155
                  C   C   AGHG C   +     C C  G+ GP C    EQ C         + 
Sbjct: 775  GHWGPDCSHPCNCSAGHGSCDAISG---LCLCEAGYVGPRC----EQQCPQGHFGPGCEQ 827

Query: 1156 LVDCEDPECCQ--SPAC 1170
            L  C+    C   S AC
Sbjct: 828  LCQCQHGAACDHVSGAC 844



 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 87/309 (28%), Positives = 112/309 (36%), Gaps = 68/309 (22%)

Query: 881  GCSGKGEC--LMGHCQCQPGFGGDDCSK--------SVCPVLCS----QRGEYINGECQC 926
            GC   G C    G C C  G+ GD C            C   CS        ++ G C+C
Sbjct: 916  GCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPAAACHHVTGACRC 975

Query: 927  NPGWKGKECSL-----RHDE-CE-VPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPH- 976
             PG+ G  C       R+   CE +  C   G C    G C C  G+ G  C  + CP  
Sbjct: 976  PPGFTGSGCEQGCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCN-LTCPQG 1034

Query: 977  ---PTCS-----GHGFC---IEGTCVCKKGWKGADCGT---MDKDALQCLPDCS--GHGT 1020
               P C+     G G     + GTC+C  G  G  C      ++  + C   CS    G 
Sbjct: 1035 RFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGL 1094

Query: 1021 FDVDTQTCSCHAKWSGEDCSKE--------VCSLECGPHGRCVGE----SCSCAAGWSGE 1068
                  +CSC   W+G  C            C LEC  H     E    +C C  G+ G+
Sbjct: 1095 CHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQ 1154

Query: 1069 FCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKC 1128
             C  R   A C  +  C+ G         G  CTL  C   C G   C   +    +C C
Sbjct: 1155 ACEHRRSGATC--NLDCRRGQF-------GPSCTLH-C--DCGGGADC---DPVSGQCHC 1199

Query: 1129 FDGWDGPDC 1137
             DG+ GP C
Sbjct: 1200 VDGYMGPTC 1208



 Score = 86.6 bits (205), Expect = 1e-15
 Identities = 91/320 (28%), Positives = 117/320 (36%), Gaps = 69/320 (21%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            CP G  G       H  C  GF G DC +S C        + +NG C C  G +G  C+ 
Sbjct: 846  CPAGWRGT---FCEHA-CPAGFFGLDC-RSACNCTAGAACDAVNGSCLCPAGRRGPRCAE 900

Query: 938  RHDECEV-PDCNGHGHCVNG--------KCSCVRGYKGKFC---------GEIDCPHPTC 979
            +    +V   C   G C+NG        +C C  G+ G  C         GE      +C
Sbjct: 901  KCLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSC 960

Query: 980  SGHGFC--IEGTCVCKKGWKGADC------GTMDKDALQCLPDCSGHGTFDVDTQTCSCH 1031
                 C  + G C C  G+ G+ C      G       Q L  C   G+ D  T  C C 
Sbjct: 961  PPAAACHHVTGACRCPPGFTGSGCEQGCPPGRYGPGCEQ-LCGCLNGGSCDAATGACRCP 1019

Query: 1032 AKWSGEDCS------------KEVCSLECGPHGRC--VGESCSCAAGWSGEFCSVRL--- 1074
              + G DC+              VC   CG    C  V  +C C  G +G  C       
Sbjct: 1020 TGFLGTDCNLTCPQGRFGPNCTHVCG--CGQGAACDPVTGTCLCPPGRAGVRCERGCPQN 1077

Query: 1075 -----CDARCA--EHGQC--KNGTCLCVSGWNGRHCTLEGCP---RSCAGHGQCRVDNDG 1122
                 C+  C+    G C   NG+C C  GW GRHC L  CP      A H +C   N+ 
Sbjct: 1078 RFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCEL-ACPPGRYGAACHLECSCHNNS 1136

Query: 1123 RWE-----CKCFDGWDGPDC 1137
              E     C+C  G+ G  C
Sbjct: 1137 TCEPATGTCRCGPGFYGQAC 1156



 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 88/306 (28%), Positives = 115/306 (37%), Gaps = 57/306 (18%)

Query: 901  GDDCSKSVCPVLCSQRGEYING--ECQCNPGWKGKECS------LRHDECEVP-DCNGHG 951
            G DCS + C   C   G  + G   C C  GW G  C+           C     C   G
Sbjct: 429  GHDCSLT-CDD-CRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGG 486

Query: 952  HC--VNGKCSCVRGYKGKFCGEIDCPHP----------TCSGHGFC--IEGTCVCKKGWK 997
             C  V G C C  G  G  C E  CP             C+  G C  + G C+C  G  
Sbjct: 487  TCDSVTGACRCPPGVSGTNC-EDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLY 545

Query: 998  GADCG-TMDKDAL--QCLPDC---SGH-GTFDVDTQTCSCHAKWSGEDCSKEVCSLECGP 1050
            G  C  T    A    C  +C     H  + D    +CSC A + GE C  E C  E G 
Sbjct: 546  GRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAE-C--ELGY 602

Query: 1051 HGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSC 1110
             G    ++C+C  G + +  S   C  RC    Q ++    C  G  G +C+   C  SC
Sbjct: 603  FGPGCWQACTCPVGVACDSVSGE-CGKRCPAGFQGEDCGQECPVGTFGVNCS-SSC--SC 658

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
             G   C   +    +C+C  G  G DC    E  C + R       + C+  E C  PAC
Sbjct: 659  GG-APC---HGVTGQCRCPPGRTGEDC----EADCPEGRWG-----LGCQ--EIC--PAC 701

Query: 1171 KSSQLC 1176
            + +  C
Sbjct: 702  QHAARC 707



 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 52/189 (27%), Positives = 66/189 (34%), Gaps = 45/189 (23%)

Query: 875  THNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--------CPVLCSQRGEYI----NG 922
            TH C  G     + + G C C PG  G  C +          C   CS R   +    NG
Sbjct: 1041 THVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNG 1100

Query: 923  ECQCNPGWKGKECSLR----------HDECEVPDCNGHGHC--VNGKCSCVRGYKGKFCG 970
             C C  GW G+ C L           H EC    C+ +  C    G C C  G+ G+ C 
Sbjct: 1101 SCSCGLGWTGRHCELACPPGRYGAACHLEC---SCHNNSTCEPATGTCRCGPGFYGQAC- 1156

Query: 971  EIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSC 1030
            E      TC+           C++G  G  C       L C  DC G    D  +  C C
Sbjct: 1157 EHRRSGATCN---------LDCRRGQFGPSC------TLHC--DCGGGADCDPVSGQCHC 1199

Query: 1031 HAKWSGEDC 1039
               + G  C
Sbjct: 1200 VDGYMGPTC 1208



 Score = 47.6 bits (108), Expect = 7e-04
 Identities = 41/128 (32%), Positives = 51/128 (39%), Gaps = 30/128 (23%)

Query: 873  EMTHNCPNG--C-SGKGECLMG------HCQ--CQPGFGGDDCSKSVCPVLCSQRGEYIN 921
            E T +C NG  C +  G C  G      HC+  C PG  G  C    C    +   E   
Sbjct: 1084 EHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLE-CSCHNNSTCEPAT 1142

Query: 922  GECQCNPGWKGKECSLRHD--ECEVP--------------DCNGHGHC--VNGKCSCVRG 963
            G C+C PG+ G+ C  R     C +               DC G   C  V+G+C CV G
Sbjct: 1143 GTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDG 1202

Query: 964  YKGKFCGE 971
            Y G  C E
Sbjct: 1203 YMGPTCRE 1210



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 69/256 (26%), Positives = 95/256 (37%), Gaps = 45/256 (17%)

Query: 893  CQCQPGF----GGDDC-SKSVCP---VLCSQRGEYING--ECQCNPGWK----GKECSLR 938
            CQC+PGF     G  C  +S C      C  R + + G   C+C+ G++    GK C   
Sbjct: 139  CQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-D 197

Query: 939  HDECE--VPDCNGHGHCVNG----KCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVC 992
             DEC   +  C  HG C+N     KC C  GY      E+      C      I  +C  
Sbjct: 198  VDECAAGLAQC-AHG-CLNTQGSFKCVCHAGY------ELGADGRQCYRIEMEIVNSCEA 249

Query: 993  KKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHG 1052
              G     C       L C   C      D D +TC      +   C ++VC+   G   
Sbjct: 250  NNGGCSHGCSHTSAGPL-C--TCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPG--- 303

Query: 1053 RCVGESCSCAAGW--SGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHC----TLEGC 1106
               G  C C AG+  S + C     D   +  G C++  C  ++G     C     L   
Sbjct: 304  ---GYECGCYAGYRLSADGCGCEDVDECASSRGGCEH-HCTNLAGSFQCSCEAGYRLHED 359

Query: 1107 PRSCAGHGQCRVDNDG 1122
             R C+   +  VD DG
Sbjct: 360  RRGCSPLEEPMVDLDG 375



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 55/182 (30%), Positives = 63/182 (34%), Gaps = 44/182 (24%)

Query: 991  VCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSG----EDCSKEV--- 1043
            VC     G DC      +L C  DC   GT  +    C C   W+G    E C  +    
Sbjct: 422  VCLDDSFGHDC------SLTC-DDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGK 474

Query: 1044 -CSLECGPH--GRC--VGESCSCAAGWSGEFCS--------VRLC--DARCAEHGQCKN- 1087
             CS  C     G C  V  +C C  G SG  C          + C     CA  G+C   
Sbjct: 475  NCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL 534

Query: 1088 -GTCLCVSGWNGRHCTL--------EGCPRSC---AGHGQCRVDNDGRWECKCFDGWDGP 1135
             G CLC  G  GR C L         GC   C     H Q     DG   C C  G+ G 
Sbjct: 535  YGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDG--SCSCKAGFRGE 592

Query: 1136 DC 1137
             C
Sbjct: 593  RC 594



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 58/252 (23%), Positives = 91/252 (36%), Gaps = 42/252 (16%)

Query: 924  CQCNPGWK----GKECSLRHDECEVPDCNGHGHCVN-----GKCSCVRGYKGKFCGEIDC 974
            C+C PG++     + C L  + C + +     HCV       +C C  G++ +  G    
Sbjct: 97   CECKPGFRLHTDSRTC-LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 155

Query: 975  PHPTCSG-HGFCIE--------GTCVCKKGWKGADCGTMDKDALQC---LPDCSGHGTFD 1022
                C+  +G C+           C C  G++ A  G   +D  +C   L  C+ HG  +
Sbjct: 156  RRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCA-HGCLN 214

Query: 1023 VDTQ-TCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE 1081
                  C CHA +      ++   +E      C   +  C+ G S       LC      
Sbjct: 215  TQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGP-LCTCPRGY 273

Query: 1082 HGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGW----DGPDC 1137
                   TC+ V       C    C + C        +N G +EC C+ G+    DG  C
Sbjct: 274  ELDTDQRTCIDVDDCADSPC----CQQVCT-------NNPGGYECGCYAGYRLSADGCGC 322

Query: 1138 TTLKEQICDDSR 1149
              + E  C  SR
Sbjct: 323  EDVDE--CASSR 332


>AB008375-1|BAA22994.1|  403|Homo sapiens osteoblast specific
            cysteine-rich protein protein.
          Length = 403

 Score =   99 bits (238), Expect = 1e-19
 Identities = 94/299 (31%), Positives = 114/299 (38%), Gaps = 82/299 (27%)

Query: 882  CSGKGECLMGHCQCQPGFGGDDC----------SKSVCP----VLCSQRGEYINGECQCN 927
            C G G+C  G+C C+ G+ GD C          SK  C      +CS RG  + GEC C+
Sbjct: 103  CGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCH 162

Query: 928  P-----GW---KGKECSLRHDECE-VPD------CNGHGHCVNGKCSCVRGYKGKFC--- 969
                   W    G  C     +C  V D      C+GHG C  G+C C  G+ GK C   
Sbjct: 163  DVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYGKKCEHP 222

Query: 970  ---------------GEIDCPHPTCSGHGFCIEGTCVC-KKGWKGADCGTMDKDALQCLP 1013
                           G  D P   CSG G C  G C C   G +     T + D  +C  
Sbjct: 223  QSCTLSAEESIRKCQGSSDLP---CSGRGKCECGKCTCYPPGDRRVYGKTCECDDRRCED 279

Query: 1014 ----DCSGHGTFDVDTQTCSCHAKWSGEDC------------SKEVC----SLECGPHGR 1053
                 C GHGT       C C   W G+ C            SK +C     + C   G 
Sbjct: 280  LDGVVCGGHGT--CSCGRCVCERGWFGKLCQHPRKCNMTEEQSKNLCESADGILCSGKGS 337

Query: 1054 CVGESCSCAA-GW--SGEFCSV--RLCDAR----CAEHGQCKNGTCLCVSGWNGRHCTL 1103
            C    C C+A  W  SGEFC    R CD      C  +G C  G C C  GWNG  C +
Sbjct: 338  CHCGKCICSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEI 396



 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 83/284 (29%), Positives = 103/284 (36%), Gaps = 44/284 (15%)

Query: 922  GECQCNPGWKGKECSL----------RHDECEVPD---CNGHGHCVNGKCSCVRG----- 963
            G+C+C+ GW G  C             +  C+      C+  G C  G+C C        
Sbjct: 22   GKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICSNSGTCHCGRCKCDNSDGSGL 81

Query: 964  YKGKFC--GEIDC----PHPTCSGHGFCIEGTCVCKKGWKGADCG-TMDKDALQCLPDC- 1015
              GKFC   + +C        C GHG C  G C CK GW G  C    D    +    C 
Sbjct: 82   VYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCT 141

Query: 1016 SGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLC 1075
            S  G    +  TC C     GE    +V     G  G   G++C C           R  
Sbjct: 142  SPDGKICSNRGTCVC-----GECTCHDVD--PTGDWGDIHGDTCECDER-DCRAVYDRYS 193

Query: 1076 DARCAEHGQCKNGTCLCVSGWNGRHC--------TLEGCPRSCAGHGQCRVDNDGRWEC- 1126
            D  C+ HGQC  G C C +GW G+ C        + E   R C G         G+ EC 
Sbjct: 194  DDFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECG 253

Query: 1127 KCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPAC 1170
            KC     G      K   CDD R  D DG+V C     C    C
Sbjct: 254  KCTCYPPGDRRVYGKTCECDDRRCEDLDGVV-CGGHGTCSCGRC 296



 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 81/257 (31%), Positives = 106/257 (41%), Gaps = 62/257 (24%)

Query: 879  PNG--CSGKGECLMGHCQCQP----GFGGD------DCSKSVCPVL--------CSQRGE 918
            P+G  CS +G C+ G C C      G  GD      +C +  C  +        CS  G+
Sbjct: 143  PDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQ 202

Query: 919  YINGECQCNPGWKGKEC------SLRHDE----CEVPD---CNGHGHCVNGKCSCV---- 961
               G C C  GW GK+C      +L  +E    C+      C+G G C  GKC+C     
Sbjct: 203  CNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGD 262

Query: 962  RGYKGKFCGEID--CPH---PTCSGHGFCIEGTCVCKKGWKGADCG-----TMDKDALQC 1011
            R   GK C   D  C       C GHG C  G CVC++GW G  C       M ++  + 
Sbjct: 263  RRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQHPRKCNMTEEQSKN 322

Query: 1012 LPD------CSGHGTFDVDTQTCSCHAKW--SGE--DCSKEVCS----LECGPHGRCVGE 1057
            L +      CSG G+       CS   +W  SGE  DC    C     L C  +G C   
Sbjct: 323  LCESADGILCSGKGSCHCGKCICSAE-EWYISGEFCDCDDRDCDKHDGLICTGNGICSCG 381

Query: 1058 SCSCAAGWSGEFCSVRL 1074
            +C C  GW+G  C + L
Sbjct: 382  NCECWDGWNGNACEIWL 398



 Score = 85.0 bits (201), Expect = 4e-15
 Identities = 100/371 (26%), Positives = 132/371 (35%), Gaps = 96/371 (25%)

Query: 890  MGHCQCQPGFGGDDC------------SKSVC----PVLCSQRGEYINGECQCNPG---- 929
            +G C+C  G+ GD C            S  +C     ++CS  G    G C+C+      
Sbjct: 21   VGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICSNSGTCHCGRCKCDNSDGSG 80

Query: 930  -WKGKECSLRHDEC---EVPD-CNGHGHCVNGKCSCVRGYKGKFC----------GEIDC 974
               GK C     EC   E  + C GHG C  G C C  G+ G  C           +  C
Sbjct: 81   LVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRC 140

Query: 975  PHP---TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQC-------LPD------CSGH 1018
              P    CS  G C+ G C C       D G +  D  +C       + D      CSGH
Sbjct: 141  TSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGH 200

Query: 1019 GTFDVDTQTCSCHAKWSGEDCS-KEVCSLE---------------CGPHGRCVGESCSC- 1061
            G    +   C C A W G+ C   + C+L                C   G+C    C+C 
Sbjct: 201  G--QCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCY 258

Query: 1062 ------AAGWSGEFCSVRLCD----ARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSC- 1110
                    G + E C  R C+      C  HG C  G C+C  GW G+ C     PR C 
Sbjct: 259  PPGDRRVYGKTCE-CDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQ---HPRKCN 314

Query: 1111 ----AGHGQCRVDN----DGRWECKCFDGWDGPDCTTLKEQICD-DSRDNDK-DGLVDCE 1160
                     C   +     G+  C C       +   +  + CD D RD DK DGL+ C 
Sbjct: 315  MTEEQSKNLCESADGILCSGKGSCHCGKCICSAEEWYISGEFCDCDDRDCDKHDGLI-CT 373

Query: 1161 DPECCQSPACK 1171
                C    C+
Sbjct: 374  GNGICSCGNCE 384


>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
            protein.
          Length = 1534

 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 74/239 (30%), Positives = 103/239 (43%), Gaps = 38/239 (15%)

Query: 940  DECEVPDCNGHGHCVNG-----KCSCVRGYKGKFCG-EID-CPHPTCSGHGFCI--EG-- 988
            D C    C   G C N      +C+C  GYKG+ C   +D C    C   G C   EG  
Sbjct: 927  DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK--EV 1043
               TC C  G++G  CG    D +       G     V   TC C  ++ G+ C +  ++
Sbjct: 987  APFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDL 1046

Query: 1044 CSLECGP---HGRCVGES----CSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG----T 1089
            CS +  P     +CVG      C C  G++G+ CS     C D RC    QC +     +
Sbjct: 1047 CSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106

Query: 1090 CLCVSGWNGRHCTLEG---CPRS-CAG----HGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
            CLC  G++G+ C +      P+S C G    +G   VD   R  C+C  G+ GP+C  L
Sbjct: 1107 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1165



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 58/196 (29%), Positives = 78/196 (39%), Gaps = 28/196 (14%)

Query: 1011 CLPD-CSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSLECGP---HGRC---VGE--- 1057
            CL   C   GT   D      C+C + + G DC   + S   GP    G C    GE   
Sbjct: 929  CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 988

Query: 1058 -SCSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG----TCLCVSGWNGRHCT--LEGCP 1107
             +CSC  G+ G  C V    C D  CA  G C +G    TC C   + G+ C   ++ C 
Sbjct: 989  FTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS 1048

Query: 1108 ---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                 C    QC    DG   C+C  G+ G +C+  ++  C D R  +    +D  +   
Sbjct: 1049 PDLNPCQHEAQCVGTPDGP-RCECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNSYS 1106

Query: 1165 CQSPACKSSQLCVSSP 1180
            C      S QLC   P
Sbjct: 1107 CLCAEGYSGQLCEIPP 1122



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 40/125 (32%), Positives = 45/125 (36%), Gaps = 18/125 (14%)

Query: 894  QCQPGF--GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD-ECEVPDCNGH 950
            Q +PG   G + C K  C     Q        C C  GW G  C    D  C    C  H
Sbjct: 1330 QMKPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKC-VH 1388

Query: 951  GHCV-----NGKCSCVRGYKGKFCGEIDCPHPTCSG----HGFC-IEGT----CVCKKGW 996
            G CV     +  C C  GY G  C +       C G    HG C   GT    CVC  G+
Sbjct: 1389 GQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGF 1448

Query: 997  KGADC 1001
             G  C
Sbjct: 1449 SGELC 1453



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 39/128 (30%), Positives = 46/128 (35%), Gaps = 15/128 (11%)

Query: 1037 EDCSKEVCSLE-CGPHGRCVGESCSCAAGWSGEFCSVRL---CDARCAEHGQC-----KN 1087
            E C K  C    C P+    G  C C AGW G  C       C      HGQC      +
Sbjct: 1340 EPCRKLYCLHGICQPNAT-PGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALS 1398

Query: 1088 GTCLCVSGWNGRHCTLEGC-PRSCAG----HGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
             +C C  G++G  C   G     C G    HG C+        C C  G+ G  C    E
Sbjct: 1399 YSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESE 1458

Query: 1143 QICDDSRD 1150
               D  RD
Sbjct: 1459 CRGDPVRD 1466



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 17/126 (13%)

Query: 1074 LC-DARCAEHGQCKNGT-----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDN--DG 1122
            LC  + C   G C N       C C SG+ GR C  +L+ C    C   G C      D 
Sbjct: 928  LCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDA 987

Query: 1123 RWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACKS-SQLC 1176
             + C C  G++GP C    +   D +  N     D  G   C+ P   +  AC+    LC
Sbjct: 988  PFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLC 1047

Query: 1177 VSSPKP 1182
                 P
Sbjct: 1048 SPDLNP 1053



 Score = 35.5 bits (78), Expect = 2.9
 Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 15/120 (12%)

Query: 876  HNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ---------- 925
            H C +G     + L   CQCQ G+ G  C+++       +  + ++G CQ          
Sbjct: 1384 HKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCV 1443

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C+PG+ G+ C  +  EC             G   C      +    ++C   +C G G C
Sbjct: 1444 CDPGFSGELCE-QESECRGDPVRDFHQVQRGYAIC---QTTRPLSWVEC-RGSCPGQGCC 1498


>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
            protein.
          Length = 1461

 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 74/239 (30%), Positives = 103/239 (43%), Gaps = 38/239 (15%)

Query: 940  DECEVPDCNGHGHCVNG-----KCSCVRGYKGKFCG-EID-CPHPTCSGHGFCI--EG-- 988
            D C    C   G C N      +C+C  GYKG+ C   +D C    C   G C   EG  
Sbjct: 927  DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK--EV 1043
               TC C  G++G  CG    D +       G     V   TC C  ++ G+ C +  ++
Sbjct: 987  APFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDL 1046

Query: 1044 CSLECGP---HGRCVGES----CSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG----T 1089
            CS +  P     +CVG      C C  G++G+ CS     C D RC    QC +     +
Sbjct: 1047 CSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106

Query: 1090 CLCVSGWNGRHCTLEG---CPRS-CAG----HGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
            CLC  G++G+ C +      P+S C G    +G   VD   R  C+C  G+ GP+C  L
Sbjct: 1107 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1165



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 58/196 (29%), Positives = 78/196 (39%), Gaps = 28/196 (14%)

Query: 1011 CLPD-CSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSLECGP---HGRC---VGE--- 1057
            CL   C   GT   D      C+C + + G DC   + S   GP    G C    GE   
Sbjct: 929  CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 988

Query: 1058 -SCSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG----TCLCVSGWNGRHCT--LEGCP 1107
             +CSC  G+ G  C V    C D  CA  G C +G    TC C   + G+ C   ++ C 
Sbjct: 989  FTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS 1048

Query: 1108 ---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                 C    QC    DG   C+C  G+ G +C+  ++  C D R  +    +D  +   
Sbjct: 1049 PDLNPCQHEAQCVGTPDGP-RCECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNSYS 1106

Query: 1165 CQSPACKSSQLCVSSP 1180
            C      S QLC   P
Sbjct: 1107 CLCAEGYSGQLCEIPP 1122



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 17/126 (13%)

Query: 1074 LC-DARCAEHGQCKNGT-----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDN--DG 1122
            LC  + C   G C N       C C SG+ GR C  +L+ C    C   G C      D 
Sbjct: 928  LCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDA 987

Query: 1123 RWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACKS-SQLC 1176
             + C C  G++GP C    +   D +  N     D  G   C+ P   +  AC+    LC
Sbjct: 988  PFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLC 1047

Query: 1177 VSSPKP 1182
                 P
Sbjct: 1048 SPDLNP 1053



 Score = 41.5 bits (93), Expect = 0.045
 Identities = 30/96 (31%), Positives = 34/96 (35%), Gaps = 9/96 (9%)

Query: 894  QCQPGF--GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD-ECEVPDCNGH 950
            Q +PG   G + C K  C     Q        C C  GW G  C    D  C    C  H
Sbjct: 1330 QMKPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCV-H 1388

Query: 951  GHCV-----NGKCSCVRGYKGKFCGEIDCPHPTCSG 981
            G CV     +  C C  GY G  C +      T SG
Sbjct: 1389 GQCVPLDALSYSCQCQDGYSGALCNQSPSAGGTLSG 1424



 Score = 39.5 bits (88), Expect = 0.18
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 10/65 (15%)

Query: 1082 HGQCK-NGT----CLCVSGWNGRHCTLEGCPRSCAGH----GQCRVDNDGRWECKCFDGW 1132
            HG C+ N T    C C +GW G HC  +     C GH    GQC   +   + C+C DG+
Sbjct: 1349 HGICQPNATPGPMCHCEAGWVGLHCD-QPADGPCHGHKCVHGQCVPLDALSYSCQCQDGY 1407

Query: 1133 DGPDC 1137
             G  C
Sbjct: 1408 SGALC 1412



 Score = 35.5 bits (78), Expect = 2.9
 Identities = 24/74 (32%), Positives = 29/74 (39%), Gaps = 10/74 (13%)

Query: 1037 EDCSKEVCSLE-CGPHGRCVGESCSCAAGWSGEFCSVRL---CDARCAEHGQC-----KN 1087
            E C K  C    C P+    G  C C AGW G  C       C      HGQC      +
Sbjct: 1340 EPCRKLYCLHGICQPNAT-PGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALS 1398

Query: 1088 GTCLCVSGWNGRHC 1101
             +C C  G++G  C
Sbjct: 1399 YSCQCQDGYSGALC 1412


>AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
            protein.
          Length = 1461

 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 74/239 (30%), Positives = 103/239 (43%), Gaps = 38/239 (15%)

Query: 940  DECEVPDCNGHGHCVNG-----KCSCVRGYKGKFCG-EID-CPHPTCSGHGFCI--EG-- 988
            D C    C   G C N      +C+C  GYKG+ C   +D C    C   G C   EG  
Sbjct: 927  DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK--EV 1043
               TC C  G++G  CG    D +       G     V   TC C  ++ G+ C +  ++
Sbjct: 987  APFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDL 1046

Query: 1044 CSLECGP---HGRCVGES----CSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG----T 1089
            CS +  P     +CVG      C C  G++G+ CS     C D RC    QC +     +
Sbjct: 1047 CSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106

Query: 1090 CLCVSGWNGRHCTLEG---CPRS-CAG----HGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
            CLC  G++G+ C +      P+S C G    +G   VD   R  C+C  G+ GP+C  L
Sbjct: 1107 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1165



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 58/196 (29%), Positives = 78/196 (39%), Gaps = 28/196 (14%)

Query: 1011 CLPD-CSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSLECGP---HGRC---VGE--- 1057
            CL   C   GT   D      C+C + + G DC   + S   GP    G C    GE   
Sbjct: 929  CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 988

Query: 1058 -SCSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG----TCLCVSGWNGRHCT--LEGCP 1107
             +CSC  G+ G  C V    C D  CA  G C +G    TC C   + G+ C   ++ C 
Sbjct: 989  FTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS 1048

Query: 1108 ---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                 C    QC    DG   C+C  G+ G +C+  ++  C D R  +    +D  +   
Sbjct: 1049 PDLNPCQHEAQCVGTPDGP-RCECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNSYS 1106

Query: 1165 CQSPACKSSQLCVSSP 1180
            C      S QLC   P
Sbjct: 1107 CLCAEGYSGQLCEIPP 1122



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 17/126 (13%)

Query: 1074 LC-DARCAEHGQCKNGT-----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDN--DG 1122
            LC  + C   G C N       C C SG+ GR C  +L+ C    C   G C      D 
Sbjct: 928  LCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDA 987

Query: 1123 RWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACKS-SQLC 1176
             + C C  G++GP C    +   D +  N     D  G   C+ P   +  AC+    LC
Sbjct: 988  PFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLC 1047

Query: 1177 VSSPKP 1182
                 P
Sbjct: 1048 SPDLNP 1053



 Score = 41.5 bits (93), Expect = 0.045
 Identities = 30/96 (31%), Positives = 34/96 (35%), Gaps = 9/96 (9%)

Query: 894  QCQPGF--GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD-ECEVPDCNGH 950
            Q +PG   G + C K  C     Q        C C  GW G  C    D  C    C  H
Sbjct: 1330 QMKPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCV-H 1388

Query: 951  GHCV-----NGKCSCVRGYKGKFCGEIDCPHPTCSG 981
            G CV     +  C C  GY G  C +      T SG
Sbjct: 1389 GQCVPLDALSYSCQCQDGYSGALCNQSPSAGGTLSG 1424



 Score = 39.5 bits (88), Expect = 0.18
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 10/65 (15%)

Query: 1082 HGQCK-NGT----CLCVSGWNGRHCTLEGCPRSCAGH----GQCRVDNDGRWECKCFDGW 1132
            HG C+ N T    C C +GW G HC  +     C GH    GQC   +   + C+C DG+
Sbjct: 1349 HGICQPNATPGPMCHCEAGWVGLHCD-QPADGPCHGHKCVHGQCVPLDALSYSCQCQDGY 1407

Query: 1133 DGPDC 1137
             G  C
Sbjct: 1408 SGALC 1412



 Score = 35.5 bits (78), Expect = 2.9
 Identities = 24/74 (32%), Positives = 29/74 (39%), Gaps = 10/74 (13%)

Query: 1037 EDCSKEVCSLE-CGPHGRCVGESCSCAAGWSGEFCSVRL---CDARCAEHGQC-----KN 1087
            E C K  C    C P+    G  C C AGW G  C       C      HGQC      +
Sbjct: 1340 EPCRKLYCLHGICQPNAT-PGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALS 1398

Query: 1088 GTCLCVSGWNGRHC 1101
             +C C  G++G  C
Sbjct: 1399 YSCQCQDGYSGALC 1412


>AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
            protein.
          Length = 1534

 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 74/239 (30%), Positives = 103/239 (43%), Gaps = 38/239 (15%)

Query: 940  DECEVPDCNGHGHCVNG-----KCSCVRGYKGKFCG-EID-CPHPTCSGHGFCI--EG-- 988
            D C    C   G C N      +C+C  GYKG+ C   +D C    C   G C   EG  
Sbjct: 927  DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK--EV 1043
               TC C  G++G  CG    D +       G     V   TC C  ++ G+ C +  ++
Sbjct: 987  APFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDL 1046

Query: 1044 CSLECGP---HGRCVGES----CSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG----T 1089
            CS +  P     +CVG      C C  G++G+ CS     C D RC    QC +     +
Sbjct: 1047 CSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106

Query: 1090 CLCVSGWNGRHCTLEG---CPRS-CAG----HGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
            CLC  G++G+ C +      P+S C G    +G   VD   R  C+C  G+ GP+C  L
Sbjct: 1107 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1165



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 58/196 (29%), Positives = 78/196 (39%), Gaps = 28/196 (14%)

Query: 1011 CLPD-CSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSLECGP---HGRC---VGE--- 1057
            CL   C   GT   D      C+C + + G DC   + S   GP    G C    GE   
Sbjct: 929  CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 988

Query: 1058 -SCSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG----TCLCVSGWNGRHCT--LEGCP 1107
             +CSC  G+ G  C V    C D  CA  G C +G    TC C   + G+ C   ++ C 
Sbjct: 989  FTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS 1048

Query: 1108 ---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                 C    QC    DG   C+C  G+ G +C+  ++  C D R  +    +D  +   
Sbjct: 1049 PDLNPCQHEAQCVGTPDGP-RCECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNSYS 1106

Query: 1165 CQSPACKSSQLCVSSP 1180
            C      S QLC   P
Sbjct: 1107 CLCAEGYSGQLCEIPP 1122



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 40/125 (32%), Positives = 45/125 (36%), Gaps = 18/125 (14%)

Query: 894  QCQPGF--GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD-ECEVPDCNGH 950
            Q +PG   G + C K  C     Q        C C  GW G  C    D  C    C  H
Sbjct: 1330 QMKPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKC-VH 1388

Query: 951  GHCV-----NGKCSCVRGYKGKFCGEIDCPHPTCSG----HGFC-IEGT----CVCKKGW 996
            G CV     +  C C  GY G  C +       C G    HG C   GT    CVC  G+
Sbjct: 1389 GQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGF 1448

Query: 997  KGADC 1001
             G  C
Sbjct: 1449 SGELC 1453



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 39/128 (30%), Positives = 46/128 (35%), Gaps = 15/128 (11%)

Query: 1037 EDCSKEVCSLE-CGPHGRCVGESCSCAAGWSGEFCSVRL---CDARCAEHGQC-----KN 1087
            E C K  C    C P+    G  C C AGW G  C       C      HGQC      +
Sbjct: 1340 EPCRKLYCLHGICQPNAT-PGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALS 1398

Query: 1088 GTCLCVSGWNGRHCTLEGC-PRSCAG----HGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
             +C C  G++G  C   G     C G    HG C+        C C  G+ G  C    E
Sbjct: 1399 YSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESE 1458

Query: 1143 QICDDSRD 1150
               D  RD
Sbjct: 1459 CRGDPVRD 1466



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 17/126 (13%)

Query: 1074 LC-DARCAEHGQCKNGT-----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDN--DG 1122
            LC  + C   G C N       C C SG+ GR C  +L+ C    C   G C      D 
Sbjct: 928  LCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDA 987

Query: 1123 RWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACKS-SQLC 1176
             + C C  G++GP C    +   D +  N     D  G   C+ P   +  AC+    LC
Sbjct: 988  PFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLC 1047

Query: 1177 VSSPKP 1182
                 P
Sbjct: 1048 SPDLNP 1053



 Score = 35.5 bits (78), Expect = 2.9
 Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 15/120 (12%)

Query: 876  HNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ---------- 925
            H C +G     + L   CQCQ G+ G  C+++       +  + ++G CQ          
Sbjct: 1384 HKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCV 1443

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C+PG+ G+ C  +  EC             G   C      +    ++C   +C G G C
Sbjct: 1444 CDPGFSGELCE-QESECRGDPVRDFHQVQRGYAIC---QTTRPLSWVEC-RGSCPGQGCC 1498


>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
          Length = 1618

 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 74/239 (30%), Positives = 103/239 (43%), Gaps = 38/239 (15%)

Query: 940  DECEVPDCNGHGHCVNG-----KCSCVRGYKGKFCG-EID-CPHPTCSGHGFCI--EG-- 988
            D C    C   G C N      +C+C  GYKG+ C   +D C    C   G C   EG  
Sbjct: 1011 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 1070

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK--EV 1043
               TC C  G++G  CG    D +       G     V   TC C  ++ G+ C +  ++
Sbjct: 1071 APFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDL 1130

Query: 1044 CSLECGP---HGRCVGES----CSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG----T 1089
            CS +  P     +CVG      C C  G++G+ CS     C D RC    QC +     +
Sbjct: 1131 CSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1190

Query: 1090 CLCVSGWNGRHCTLEG---CPRS-CAG----HGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
            CLC  G++G+ C +      P+S C G    +G   VD   R  C+C  G+ GP+C  L
Sbjct: 1191 CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1249



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 58/196 (29%), Positives = 78/196 (39%), Gaps = 28/196 (14%)

Query: 1011 CLPD-CSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSLECGP---HGRC---VGE--- 1057
            CL   C   GT   D      C+C + + G DC   + S   GP    G C    GE   
Sbjct: 1013 CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 1072

Query: 1058 -SCSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG----TCLCVSGWNGRHCT--LEGCP 1107
             +CSC  G+ G  C V    C D  CA  G C +G    TC C   + G+ C   ++ C 
Sbjct: 1073 FTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS 1132

Query: 1108 ---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                 C    QC    DG   C+C  G+ G +C+  ++  C D R  +    +D  +   
Sbjct: 1133 PDLNPCQHEAQCVGTPDGP-RCECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNSYS 1190

Query: 1165 CQSPACKSSQLCVSSP 1180
            C      S QLC   P
Sbjct: 1191 CLCAEGYSGQLCEIPP 1206



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 40/125 (32%), Positives = 45/125 (36%), Gaps = 18/125 (14%)

Query: 894  QCQPGF--GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD-ECEVPDCNGH 950
            Q +PG   G + C K  C     Q        C C  GW G  C    D  C    C  H
Sbjct: 1414 QMKPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKC-VH 1472

Query: 951  GHCV-----NGKCSCVRGYKGKFCGEIDCPHPTCSG----HGFC-IEGT----CVCKKGW 996
            G CV     +  C C  GY G  C +       C G    HG C   GT    CVC  G+
Sbjct: 1473 GQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGF 1532

Query: 997  KGADC 1001
             G  C
Sbjct: 1533 SGELC 1537



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 39/128 (30%), Positives = 46/128 (35%), Gaps = 15/128 (11%)

Query: 1037 EDCSKEVCSLE-CGPHGRCVGESCSCAAGWSGEFCSVRL---CDARCAEHGQC-----KN 1087
            E C K  C    C P+    G  C C AGW G  C       C      HGQC      +
Sbjct: 1424 EPCRKLYCLHGICQPNAT-PGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALS 1482

Query: 1088 GTCLCVSGWNGRHCTLEGC-PRSCAG----HGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
             +C C  G++G  C   G     C G    HG C+        C C  G+ G  C    E
Sbjct: 1483 YSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESE 1542

Query: 1143 QICDDSRD 1150
               D  RD
Sbjct: 1543 CRGDPVRD 1550



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 17/126 (13%)

Query: 1074 LC-DARCAEHGQCKNGT-----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDN--DG 1122
            LC  + C   G C N       C C SG+ GR C  +L+ C    C   G C      D 
Sbjct: 1012 LCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDA 1071

Query: 1123 RWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACKS-SQLC 1176
             + C C  G++GP C    +   D +  N     D  G   C+ P   +  AC+    LC
Sbjct: 1072 PFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLC 1131

Query: 1177 VSSPKP 1182
                 P
Sbjct: 1132 SPDLNP 1137



 Score = 35.5 bits (78), Expect = 2.9
 Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 15/120 (12%)

Query: 876  HNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ---------- 925
            H C +G     + L   CQCQ G+ G  C+++       +  + ++G CQ          
Sbjct: 1468 HKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCV 1527

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C+PG+ G+ C  +  EC             G   C      +    ++C   +C G G C
Sbjct: 1528 CDPGFSGELCE-QESECRGDPVRDFHQVQRGYAIC---QTTRPLSWVEC-RGSCPGQGCC 1582


>AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precursor
            protein.
          Length = 1406

 Score = 96.3 bits (229), Expect = 1e-18
 Identities = 85/307 (27%), Positives = 122/307 (39%), Gaps = 48/307 (15%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGG--DDCSKSVCPVL---CSQRGEYIN--GE--- 923
            ++++C N  + K       C C         DC     P     C      +N  GE   
Sbjct: 35   LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94

Query: 924  -CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEID---CP 975
             C+C PG+ G  C      C    C   G C    +   C C  GY G+FC EID   C 
Sbjct: 95   LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-EIDHDECA 153

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTC 1028
               C     C +G    +C C  G++G  C   D +  +C  D C    T   ++   TC
Sbjct: 154  SSPCQNGAVCQDGIDGYSCFCVPGYQGRHC---DLEVDECASDPCKNEATCLNEIGRYTC 210

Query: 1029 SCHAKWSGEDCSKEV--C-SLECGPHGRC---VGE-SCSCAAGWSGEFCSVRL--CDAR- 1078
             C   +SG +C  E+  C S  C     C   +G   C CA G+ G+ C +    C ++ 
Sbjct: 211  ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQP 270

Query: 1079 CAEHGQCKNG----TCLCV-SGWNGRHC--TLEGC-PRSCAGHGQCRVDNDGRWECKCFD 1130
            C   G C +G    +C C  SG+ G HC   +  C  + C  +  C  D+   + C C+ 
Sbjct: 271  CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCE-DSVDNYTCHCWP 329

Query: 1131 GWDGPDC 1137
            G+ G  C
Sbjct: 330  GYTGAQC 336



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 84/304 (27%), Positives = 124/304 (40%), Gaps = 51/304 (16%)

Query: 870  VAEEMTHNC-PNGCSGKGEC----LMGHCQCQPGFGG-------DDCSKSVCP--VLCSQ 915
            + E    +C  N C   G C    +   C C  G+ G       D+C+ S C    +C Q
Sbjct: 106  ICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-Q 164

Query: 916  RGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCG 970
             G  I+G  C C PG++G+ C L  DEC    C     C+N  G+  C C   Y G  C 
Sbjct: 165  DG--IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 222

Query: 971  -EID-CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD 1024
             EID C    C     C +      C C  G+ G  C  ++ D  +C      HG   VD
Sbjct: 223  LEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHC-ELNTD--ECASQPCLHGGLCVD 279

Query: 1025 TQ---TCSCHAK-WSGEDCS--KEVC-SLECGPHGRCVGE----SCSCAAGWSGEFCSVR 1073
             +   +C+C    ++G  C     +C S  C  +  C       +C C  G++G  C + 
Sbjct: 280  GENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEID 339

Query: 1074 LCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
            L +  C  +    NG C+ +S    ++  + G P S + H     +  G + C C  G+ 
Sbjct: 340  LNE--CNSNPCQSNGECVELSS-EKQYGRITGLPSSFSYH-----EASG-YVCICQPGFT 390

Query: 1134 GPDC 1137
            G  C
Sbjct: 391  GIHC 394



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 55/183 (30%), Positives = 75/183 (40%), Gaps = 27/183 (14%)

Query: 919  YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID- 973
            Y +  C C  GW GK C L  DEC    C  HG+C +      C+C  GY G  C E+D 
Sbjct: 1158 YSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCTCEPGYTGVNC-EVDI 1215

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC------LPDCSGHGTF 1021
              C    C+    CI  T    C+C   + G  C      +  C      L   +G    
Sbjct: 1216 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 1022 DVDTQ-TCSCHAKWSGEDCSKEV--CSLE-CGPHGRCVG----ESCSCAAGWSGEFCSVR 1073
            +  T+  C C   ++GE C K++  C+ + C   G C        C C   ++GE C V 
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335

Query: 1074 LCD 1076
            L D
Sbjct: 1336 LAD 1338



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 67/254 (26%), Positives = 96/254 (37%), Gaps = 63/254 (24%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGEYINGE----CQCN-PG 929
            C NG + +       C C PGF GD C  +   C    C   G  ++GE    C C   G
Sbjct: 233  CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292

Query: 930  WKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEID---CPHPTCSGH 982
            + G  C      C    C+ +  C     N  C C  GY G  C EID   C    C  +
Sbjct: 293  FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQC-EIDLNECNSNPCQSN 351

Query: 983  GFCIEGT------------------------CVCKKGWKGADCGTMDKDALQCLPD-CSG 1017
            G C+E +                        C+C+ G+ G  C   ++D  +C  + C  
Sbjct: 352  GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC---EEDVNECSSNPCQN 408

Query: 1018 HGTFD--VDTQTCSC------HAKWSGEDCSKEV--CS-LECGPHGRCV--------GES 1058
             GT +      TC C         + G DCS  +  C+  +C  +G C+        G S
Sbjct: 409  GGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFS 468

Query: 1059 CSCAAGWSGEFCSV 1072
            C C +G++G  C +
Sbjct: 469  CLCPSGYTGSLCEI 482



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 1059 CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT----CLCVSGWNGRHCT--LEGCPRSC 1110
            CSC  GWSG+ C + +  C +    HG C +      C C  G+ G +C   ++ C    
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ 1222

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC--TTLKEQICDDSRDN 1151
              +G   + +   + C CF  + G  C  + L   +C + + N
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 8/73 (10%)

Query: 1072 VRLCDAR-CAEHGQCKN----GTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDGRW 1124
            + +C++  C   G C++      C C  GW+G+HC L  + C  +   HG C  D    +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS-DRVAAY 1198

Query: 1125 ECKCFDGWDGPDC 1137
             C C  G+ G +C
Sbjct: 1199 HCTCEPGYTGVNC 1211



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 24/134 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKEC-------SL 937
            HC C+PG+ G +C   +  C       G     + NG  C C   + GK C       ++
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258

Query: 938  RHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPHPTCSGHGFCIE---- 987
              +E     C   G+C       KC C  G+ G++C  +ID C    C   G C +    
Sbjct: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318

Query: 988  GTCVCKKGWKGADC 1001
              C+C   + G  C
Sbjct: 1319 FQCLCDVAFAGERC 1332


>AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precursor
            protein.
          Length = 1376

 Score = 96.3 bits (229), Expect = 1e-18
 Identities = 85/307 (27%), Positives = 122/307 (39%), Gaps = 48/307 (15%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGG--DDCSKSVCPVL---CSQRGEYIN--GE--- 923
            ++++C N  + K       C C         DC     P     C      +N  GE   
Sbjct: 35   LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94

Query: 924  -CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEID---CP 975
             C+C PG+ G  C      C    C   G C    +   C C  GY G+FC EID   C 
Sbjct: 95   LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-EIDHDECA 153

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTC 1028
               C     C +G    +C C  G++G  C   D +  +C  D C    T   ++   TC
Sbjct: 154  SSPCQNGAVCQDGIDGYSCFCVPGYQGRHC---DLEVDECASDPCKNEATCLNEIGRYTC 210

Query: 1029 SCHAKWSGEDCSKEV--C-SLECGPHGRC---VGE-SCSCAAGWSGEFCSVRL--CDAR- 1078
             C   +SG +C  E+  C S  C     C   +G   C CA G+ G+ C +    C ++ 
Sbjct: 211  ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQP 270

Query: 1079 CAEHGQCKNG----TCLCV-SGWNGRHC--TLEGC-PRSCAGHGQCRVDNDGRWECKCFD 1130
            C   G C +G    +C C  SG+ G HC   +  C  + C  +  C  D+   + C C+ 
Sbjct: 271  CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCE-DSVDNYTCHCWP 329

Query: 1131 GWDGPDC 1137
            G+ G  C
Sbjct: 330  GYTGAQC 336



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 84/304 (27%), Positives = 124/304 (40%), Gaps = 51/304 (16%)

Query: 870  VAEEMTHNC-PNGCSGKGEC----LMGHCQCQPGFGG-------DDCSKSVCP--VLCSQ 915
            + E    +C  N C   G C    +   C C  G+ G       D+C+ S C    +C Q
Sbjct: 106  ICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-Q 164

Query: 916  RGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCG 970
             G  I+G  C C PG++G+ C L  DEC    C     C+N  G+  C C   Y G  C 
Sbjct: 165  DG--IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 222

Query: 971  -EID-CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD 1024
             EID C    C     C +      C C  G+ G  C  ++ D  +C      HG   VD
Sbjct: 223  LEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHC-ELNTD--ECASQPCLHGGLCVD 279

Query: 1025 TQ---TCSCHAK-WSGEDCS--KEVC-SLECGPHGRCVGE----SCSCAAGWSGEFCSVR 1073
             +   +C+C    ++G  C     +C S  C  +  C       +C C  G++G  C + 
Sbjct: 280  GENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEID 339

Query: 1074 LCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
            L +  C  +    NG C+ +S    ++  + G P S + H     +  G + C C  G+ 
Sbjct: 340  LNE--CNSNPCQSNGECVELSS-EKQYGRITGLPSSFSYH-----EASG-YVCICQPGFT 390

Query: 1134 GPDC 1137
            G  C
Sbjct: 391  GIHC 394



 Score = 70.5 bits (165), Expect = 8e-11
 Identities = 61/234 (26%), Positives = 89/234 (38%), Gaps = 40/234 (17%)

Query: 850  WFLSLYNDDGDPQEISFVALVAEEMTHNC-------PNGCSGKGEC----LMGHCQCQPG 898
            +F +++     PQE  F+ +    +   C        N C   G C       HC C  G
Sbjct: 1109 YFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLG 1168

Query: 899  FGGDDCSKSV--C---PVLCSQRGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            + G  C  ++  C   P +     + +    C C PG+ G  C +  D C+   C     
Sbjct: 1169 WSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT 1228

Query: 953  CV---NG-KCSCVRGYKGKFCGEIDCPHP---------TCSGHGFCIEGT----CVCKKG 995
            C+   NG  C C   + GKFC +   P           TC   G C E      C+C+ G
Sbjct: 1229 CISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPG 1288

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CSCHAKWSGEDCSKEVCSL 1046
            + G  C   +KD  +C  D   +G    D      C C   ++GE C  +V SL
Sbjct: 1289 FTGEWC---EKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDVSSL 1339



 Score = 65.7 bits (153), Expect = 2e-09
 Identities = 53/179 (29%), Positives = 73/179 (40%), Gaps = 27/179 (15%)

Query: 919  YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID- 973
            Y +  C C  GW GK C L  DEC    C  HG+C +      C+C  GY G  C E+D 
Sbjct: 1158 YSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCTCEPGYTGVNC-EVDI 1215

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC------LPDCSGHGTF 1021
              C    C+    CI  T    C+C   + G  C      +  C      L   +G    
Sbjct: 1216 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 1022 DVDTQ-TCSCHAKWSGEDCSKEV--CSLE-CGPHGRCVG----ESCSCAAGWSGEFCSV 1072
            +  T+  C C   ++GE C K++  C+ + C   G C        C C   ++GE C V
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 67/254 (26%), Positives = 96/254 (37%), Gaps = 63/254 (24%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGEYINGE----CQCN-PG 929
            C NG + +       C C PGF GD C  +   C    C   G  ++GE    C C   G
Sbjct: 233  CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292

Query: 930  WKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEID---CPHPTCSGH 982
            + G  C      C    C+ +  C     N  C C  GY G  C EID   C    C  +
Sbjct: 293  FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQC-EIDLNECNSNPCQSN 351

Query: 983  GFCIEGT------------------------CVCKKGWKGADCGTMDKDALQCLPD-CSG 1017
            G C+E +                        C+C+ G+ G  C   ++D  +C  + C  
Sbjct: 352  GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC---EEDVNECSSNPCQN 408

Query: 1018 HGTFD--VDTQTCSC------HAKWSGEDCSKEV--CS-LECGPHGRCV--------GES 1058
             GT +      TC C         + G DCS  +  C+  +C  +G C+        G S
Sbjct: 409  GGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFS 468

Query: 1059 CSCAAGWSGEFCSV 1072
            C C +G++G  C +
Sbjct: 469  CLCPSGYTGSLCEI 482



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 1059 CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRSC 1110
            CSC  GWSG+ C + +  C +    HG C +      C C  G+ G +C   ++ C    
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ 1222

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC--TTLKEQICDDSRDN 1151
              +G   + +   + C CF  + G  C  + L   +C + + N
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265


>AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1
            (Drosophila) protein.
          Length = 1406

 Score = 96.3 bits (229), Expect = 1e-18
 Identities = 85/307 (27%), Positives = 122/307 (39%), Gaps = 48/307 (15%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGG--DDCSKSVCPVL---CSQRGEYIN--GE--- 923
            ++++C N  + K       C C         DC     P     C      +N  GE   
Sbjct: 35   LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94

Query: 924  -CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEID---CP 975
             C+C PG+ G  C      C    C   G C    +   C C  GY G+FC EID   C 
Sbjct: 95   LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-EIDHDECA 153

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTC 1028
               C     C +G    +C C  G++G  C   D +  +C  D C    T   ++   TC
Sbjct: 154  SSPCQNGAVCQDGIDGYSCFCVPGYQGRHC---DLEVDECASDPCKNEATCLNEIGRYTC 210

Query: 1029 SCHAKWSGEDCSKEV--C-SLECGPHGRC---VGE-SCSCAAGWSGEFCSVRL--CDAR- 1078
             C   +SG +C  E+  C S  C     C   +G   C CA G+ G+ C +    C ++ 
Sbjct: 211  ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQP 270

Query: 1079 CAEHGQCKNG----TCLCV-SGWNGRHC--TLEGC-PRSCAGHGQCRVDNDGRWECKCFD 1130
            C   G C +G    +C C  SG+ G HC   +  C  + C  +  C  D+   + C C+ 
Sbjct: 271  CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCE-DSVDNYTCHCWP 329

Query: 1131 GWDGPDC 1137
            G+ G  C
Sbjct: 330  GYTGAQC 336



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 84/304 (27%), Positives = 124/304 (40%), Gaps = 51/304 (16%)

Query: 870  VAEEMTHNC-PNGCSGKGEC----LMGHCQCQPGFGG-------DDCSKSVCP--VLCSQ 915
            + E    +C  N C   G C    +   C C  G+ G       D+C+ S C    +C Q
Sbjct: 106  ICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-Q 164

Query: 916  RGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCG 970
             G  I+G  C C PG++G+ C L  DEC    C     C+N  G+  C C   Y G  C 
Sbjct: 165  DG--IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 222

Query: 971  -EID-CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD 1024
             EID C    C     C +      C C  G+ G  C  ++ D  +C      HG   VD
Sbjct: 223  LEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHC-ELNTD--ECASQPCLHGGLCVD 279

Query: 1025 TQ---TCSCHAK-WSGEDCS--KEVC-SLECGPHGRCVGE----SCSCAAGWSGEFCSVR 1073
             +   +C+C    ++G  C     +C S  C  +  C       +C C  G++G  C + 
Sbjct: 280  GENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEID 339

Query: 1074 LCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
            L +  C  +    NG C+ +S    ++  + G P S + H     +  G + C C  G+ 
Sbjct: 340  LNE--CNSNPCQSNGECVELSS-EKQYGRITGLPSSFSYH-----EASG-YVCICQPGFT 390

Query: 1134 GPDC 1137
            G  C
Sbjct: 391  GIHC 394



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 55/183 (30%), Positives = 75/183 (40%), Gaps = 27/183 (14%)

Query: 919  YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID- 973
            Y +  C C  GW GK C L  DEC    C  HG+C +      C+C  GY G  C E+D 
Sbjct: 1158 YSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCTCEPGYTGVNC-EVDI 1215

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC------LPDCSGHGTF 1021
              C    C+    CI  T    C+C   + G  C      +  C      L   +G    
Sbjct: 1216 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 1022 DVDTQ-TCSCHAKWSGEDCSKEV--CSLE-CGPHGRCVG----ESCSCAAGWSGEFCSVR 1073
            +  T+  C C   ++GE C K++  C+ + C   G C        C C   ++GE C V 
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335

Query: 1074 LCD 1076
            L D
Sbjct: 1336 LAD 1338



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 67/254 (26%), Positives = 96/254 (37%), Gaps = 63/254 (24%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGEYINGE----CQCN-PG 929
            C NG + +       C C PGF GD C  +   C    C   G  ++GE    C C   G
Sbjct: 233  CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292

Query: 930  WKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEID---CPHPTCSGH 982
            + G  C      C    C+ +  C     N  C C  GY G  C EID   C    C  +
Sbjct: 293  FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQC-EIDLNECNSNPCQSN 351

Query: 983  GFCIEGT------------------------CVCKKGWKGADCGTMDKDALQCLPD-CSG 1017
            G C+E +                        C+C+ G+ G  C   ++D  +C  + C  
Sbjct: 352  GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC---EEDVNECSSNPCQN 408

Query: 1018 HGTFD--VDTQTCSC------HAKWSGEDCSKEV--CS-LECGPHGRCV--------GES 1058
             GT +      TC C         + G DCS  +  C+  +C  +G C+        G S
Sbjct: 409  GGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFS 468

Query: 1059 CSCAAGWSGEFCSV 1072
            C C +G++G  C +
Sbjct: 469  CLCPSGYTGSLCEI 482



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 1059 CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT----CLCVSGWNGRHCT--LEGCPRSC 1110
            CSC  GWSG+ C + +  C +    HG C +      C C  G+ G +C   ++ C    
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ 1222

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC--TTLKEQICDDSRDN 1151
              +G   + +   + C CF  + G  C  + L   +C + + N
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 8/73 (10%)

Query: 1072 VRLCDAR-CAEHGQCKN----GTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDGRW 1124
            + +C++  C   G C++      C C  GW+G+HC L  + C  +   HG C  D    +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS-DRVAAY 1198

Query: 1125 ECKCFDGWDGPDC 1137
             C C  G+ G +C
Sbjct: 1199 HCTCEPGYTGVNC 1211



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 24/134 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKEC-------SL 937
            HC C+PG+ G +C   +  C       G     + NG  C C   + GK C       ++
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258

Query: 938  RHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPHPTCSGHGFCIE---- 987
              +E     C   G+C       KC C  G+ G++C  +ID C    C   G C +    
Sbjct: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318

Query: 988  GTCVCKKGWKGADC 1001
              C+C   + G  C
Sbjct: 1319 FQCLCDVAFAGERC 1332


>AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1
            (Drosophila) protein.
          Length = 1406

 Score = 96.3 bits (229), Expect = 1e-18
 Identities = 85/307 (27%), Positives = 122/307 (39%), Gaps = 48/307 (15%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGG--DDCSKSVCPVL---CSQRGEYIN--GE--- 923
            ++++C N  + K       C C         DC     P     C      +N  GE   
Sbjct: 35   LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94

Query: 924  -CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEID---CP 975
             C+C PG+ G  C      C    C   G C    +   C C  GY G+FC EID   C 
Sbjct: 95   LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-EIDHDECA 153

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTC 1028
               C     C +G    +C C  G++G  C   D +  +C  D C    T   ++   TC
Sbjct: 154  SSPCQNGAVCQDGIDGYSCFCVPGYQGRHC---DLEVDECASDPCKNEATCLNEIGRYTC 210

Query: 1029 SCHAKWSGEDCSKEV--C-SLECGPHGRC---VGE-SCSCAAGWSGEFCSVRL--CDAR- 1078
             C   +SG +C  E+  C S  C     C   +G   C CA G+ G+ C +    C ++ 
Sbjct: 211  ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQP 270

Query: 1079 CAEHGQCKNG----TCLCV-SGWNGRHC--TLEGC-PRSCAGHGQCRVDNDGRWECKCFD 1130
            C   G C +G    +C C  SG+ G HC   +  C  + C  +  C  D+   + C C+ 
Sbjct: 271  CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCE-DSVDNYTCHCWP 329

Query: 1131 GWDGPDC 1137
            G+ G  C
Sbjct: 330  GYTGAQC 336



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 84/304 (27%), Positives = 124/304 (40%), Gaps = 51/304 (16%)

Query: 870  VAEEMTHNC-PNGCSGKGEC----LMGHCQCQPGFGG-------DDCSKSVCP--VLCSQ 915
            + E    +C  N C   G C    +   C C  G+ G       D+C+ S C    +C Q
Sbjct: 106  ICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-Q 164

Query: 916  RGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCG 970
             G  I+G  C C PG++G+ C L  DEC    C     C+N  G+  C C   Y G  C 
Sbjct: 165  DG--IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 222

Query: 971  -EID-CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD 1024
             EID C    C     C +      C C  G+ G  C  ++ D  +C      HG   VD
Sbjct: 223  LEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHC-ELNTD--ECASQPCLHGGLCVD 279

Query: 1025 TQ---TCSCHAK-WSGEDCS--KEVC-SLECGPHGRCVGE----SCSCAAGWSGEFCSVR 1073
             +   +C+C    ++G  C     +C S  C  +  C       +C C  G++G  C + 
Sbjct: 280  GENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEID 339

Query: 1074 LCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
            L +  C  +    NG C+ +S    ++  + G P S + H     +  G + C C  G+ 
Sbjct: 340  LNE--CNSNPCQSNGECVELSS-EKQYGRITGLPSSFSYH-----EASG-YVCICQPGFT 390

Query: 1134 GPDC 1137
            G  C
Sbjct: 391  GIHC 394



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 55/183 (30%), Positives = 75/183 (40%), Gaps = 27/183 (14%)

Query: 919  YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID- 973
            Y +  C C  GW GK C L  DEC    C  HG+C +      C+C  GY G  C E+D 
Sbjct: 1158 YSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCTCEPGYTGVNC-EVDI 1215

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC------LPDCSGHGTF 1021
              C    C+    CI  T    C+C   + G  C      +  C      L   +G    
Sbjct: 1216 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 1022 DVDTQ-TCSCHAKWSGEDCSKEV--CSLE-CGPHGRCVG----ESCSCAAGWSGEFCSVR 1073
            +  T+  C C   ++GE C K++  C+ + C   G C        C C   ++GE C V 
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335

Query: 1074 LCD 1076
            L D
Sbjct: 1336 LAD 1338



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 67/254 (26%), Positives = 96/254 (37%), Gaps = 63/254 (24%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGEYINGE----CQCN-PG 929
            C NG + +       C C PGF GD C  +   C    C   G  ++GE    C C   G
Sbjct: 233  CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292

Query: 930  WKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEID---CPHPTCSGH 982
            + G  C      C    C+ +  C     N  C C  GY G  C EID   C    C  +
Sbjct: 293  FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQC-EIDLNECNSNPCQSN 351

Query: 983  GFCIEGT------------------------CVCKKGWKGADCGTMDKDALQCLPD-CSG 1017
            G C+E +                        C+C+ G+ G  C   ++D  +C  + C  
Sbjct: 352  GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC---EEDVNECSSNPCQN 408

Query: 1018 HGTFD--VDTQTCSC------HAKWSGEDCSKEV--CS-LECGPHGRCV--------GES 1058
             GT +      TC C         + G DCS  +  C+  +C  +G C+        G S
Sbjct: 409  GGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFS 468

Query: 1059 CSCAAGWSGEFCSV 1072
            C C +G++G  C +
Sbjct: 469  CLCPSGYTGSLCEI 482



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 1059 CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT----CLCVSGWNGRHCT--LEGCPRSC 1110
            CSC  GWSG+ C + +  C +    HG C +      C C  G+ G +C   ++ C    
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ 1222

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC--TTLKEQICDDSRDN 1151
              +G   + +   + C CF  + G  C  + L   +C + + N
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 8/73 (10%)

Query: 1072 VRLCDAR-CAEHGQCKN----GTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDGRW 1124
            + +C++  C   G C++      C C  GW+G+HC L  + C  +   HG C  D    +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS-DRVAAY 1198

Query: 1125 ECKCFDGWDGPDC 1137
             C C  G+ G +C
Sbjct: 1199 HCTCEPGYTGVNC 1211



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 24/134 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKEC-------SL 937
            HC C+PG+ G +C   +  C       G     + NG  C C   + GK C       ++
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258

Query: 938  RHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPHPTCSGHGFCIE---- 987
              +E     C   G+C       KC C  G+ G++C  +ID C    C   G C +    
Sbjct: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318

Query: 988  GTCVCKKGWKGADC 1001
              C+C   + G  C
Sbjct: 1319 FQCLCDVAFAGERC 1332


>AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1
            (Drosophila) protein.
          Length = 1406

 Score = 96.3 bits (229), Expect = 1e-18
 Identities = 85/307 (27%), Positives = 122/307 (39%), Gaps = 48/307 (15%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGG--DDCSKSVCPVL---CSQRGEYIN--GE--- 923
            ++++C N  + K       C C         DC     P     C      +N  GE   
Sbjct: 35   LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94

Query: 924  -CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEID---CP 975
             C+C PG+ G  C      C    C   G C    +   C C  GY G+FC EID   C 
Sbjct: 95   LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-EIDHDECA 153

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTC 1028
               C     C +G    +C C  G++G  C   D +  +C  D C    T   ++   TC
Sbjct: 154  SSPCQNGAVCQDGIDGYSCFCVPGYQGRHC---DLEVDECASDPCKNEATCLNEIGRYTC 210

Query: 1029 SCHAKWSGEDCSKEV--C-SLECGPHGRC---VGE-SCSCAAGWSGEFCSVRL--CDAR- 1078
             C   +SG +C  E+  C S  C     C   +G   C CA G+ G+ C +    C ++ 
Sbjct: 211  ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQP 270

Query: 1079 CAEHGQCKNG----TCLCV-SGWNGRHC--TLEGC-PRSCAGHGQCRVDNDGRWECKCFD 1130
            C   G C +G    +C C  SG+ G HC   +  C  + C  +  C  D+   + C C+ 
Sbjct: 271  CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCE-DSVDNYTCHCWP 329

Query: 1131 GWDGPDC 1137
            G+ G  C
Sbjct: 330  GYTGAQC 336



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 84/304 (27%), Positives = 124/304 (40%), Gaps = 51/304 (16%)

Query: 870  VAEEMTHNC-PNGCSGKGEC----LMGHCQCQPGFGG-------DDCSKSVCP--VLCSQ 915
            + E    +C  N C   G C    +   C C  G+ G       D+C+ S C    +C Q
Sbjct: 106  ICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-Q 164

Query: 916  RGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCG 970
             G  I+G  C C PG++G+ C L  DEC    C     C+N  G+  C C   Y G  C 
Sbjct: 165  DG--IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 222

Query: 971  -EID-CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD 1024
             EID C    C     C +      C C  G+ G  C  ++ D  +C      HG   VD
Sbjct: 223  LEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHC-ELNTD--ECASQPCLHGGLCVD 279

Query: 1025 TQ---TCSCHAK-WSGEDCS--KEVC-SLECGPHGRCVGE----SCSCAAGWSGEFCSVR 1073
             +   +C+C    ++G  C     +C S  C  +  C       +C C  G++G  C + 
Sbjct: 280  GENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEID 339

Query: 1074 LCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
            L +  C  +    NG C+ +S    ++  + G P S + H     +  G + C C  G+ 
Sbjct: 340  LNE--CNSNPCQSNGECVELSS-EKQYGRITGLPSSFSYH-----EASG-YVCICQPGFT 390

Query: 1134 GPDC 1137
            G  C
Sbjct: 391  GIHC 394



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 55/183 (30%), Positives = 75/183 (40%), Gaps = 27/183 (14%)

Query: 919  YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID- 973
            Y +  C C  GW GK C L  DEC    C  HG+C +      C+C  GY G  C E+D 
Sbjct: 1158 YSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCTCEPGYTGVNC-EVDI 1215

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC------LPDCSGHGTF 1021
              C    C+    CI  T    C+C   + G  C      +  C      L   +G    
Sbjct: 1216 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 1022 DVDTQ-TCSCHAKWSGEDCSKEV--CSLE-CGPHGRCVG----ESCSCAAGWSGEFCSVR 1073
            +  T+  C C   ++GE C K++  C+ + C   G C        C C   ++GE C V 
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1335

Query: 1074 LCD 1076
            L D
Sbjct: 1336 LAD 1338



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 67/254 (26%), Positives = 96/254 (37%), Gaps = 63/254 (24%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGEYINGE----CQCN-PG 929
            C NG + +       C C PGF GD C  +   C    C   G  ++GE    C C   G
Sbjct: 233  CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292

Query: 930  WKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEID---CPHPTCSGH 982
            + G  C      C    C+ +  C     N  C C  GY G  C EID   C    C  +
Sbjct: 293  FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQC-EIDLNECNSNPCQSN 351

Query: 983  GFCIEGT------------------------CVCKKGWKGADCGTMDKDALQCLPD-CSG 1017
            G C+E +                        C+C+ G+ G  C   ++D  +C  + C  
Sbjct: 352  GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC---EEDVNECSSNPCQN 408

Query: 1018 HGTFD--VDTQTCSC------HAKWSGEDCSKEV--CS-LECGPHGRCV--------GES 1058
             GT +      TC C         + G DCS  +  C+  +C  +G C+        G S
Sbjct: 409  GGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFS 468

Query: 1059 CSCAAGWSGEFCSV 1072
            C C +G++G  C +
Sbjct: 469  CLCPSGYTGSLCEI 482



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 1059 CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT----CLCVSGWNGRHCT--LEGCPRSC 1110
            CSC  GWSG+ C + +  C +    HG C +      C C  G+ G +C   ++ C    
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ 1222

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC--TTLKEQICDDSRDN 1151
              +G   + +   + C CF  + G  C  + L   +C + + N
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 8/73 (10%)

Query: 1072 VRLCDAR-CAEHGQCKN----GTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDGRW 1124
            + +C++  C   G C++      C C  GW+G+HC L  + C  +   HG C  D    +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS-DRVAAY 1198

Query: 1125 ECKCFDGWDGPDC 1137
             C C  G+ G +C
Sbjct: 1199 HCTCEPGYTGVNC 1211



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 24/134 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKEC-------SL 937
            HC C+PG+ G +C   +  C       G     + NG  C C   + GK C       ++
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258

Query: 938  RHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPHPTCSGHGFCIE---- 987
              +E     C   G+C       KC C  G+ G++C  +ID C    C   G C +    
Sbjct: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318

Query: 988  GTCVCKKGWKGADC 1001
              C+C   + G  C
Sbjct: 1319 FQCLCDVAFAGERC 1332


>AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.
          Length = 1376

 Score = 96.3 bits (229), Expect = 1e-18
 Identities = 85/307 (27%), Positives = 122/307 (39%), Gaps = 48/307 (15%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGG--DDCSKSVCPVL---CSQRGEYIN--GE--- 923
            ++++C N  + K       C C         DC     P     C      +N  GE   
Sbjct: 35   LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94

Query: 924  -CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEID---CP 975
             C+C PG+ G  C      C    C   G C    +   C C  GY G+FC EID   C 
Sbjct: 95   LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-EIDHDECA 153

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTC 1028
               C     C +G    +C C  G++G  C   D +  +C  D C    T   ++   TC
Sbjct: 154  SSPCQNGAVCQDGIDGYSCFCVPGYQGRHC---DLEVDECASDPCKNEATCLNEIGRYTC 210

Query: 1029 SCHAKWSGEDCSKEV--C-SLECGPHGRC---VGE-SCSCAAGWSGEFCSVRL--CDAR- 1078
             C   +SG +C  E+  C S  C     C   +G   C CA G+ G+ C +    C ++ 
Sbjct: 211  ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQP 270

Query: 1079 CAEHGQCKNG----TCLCV-SGWNGRHC--TLEGC-PRSCAGHGQCRVDNDGRWECKCFD 1130
            C   G C +G    +C C  SG+ G HC   +  C  + C  +  C  D+   + C C+ 
Sbjct: 271  CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCE-DSVDNYTCHCWP 329

Query: 1131 GWDGPDC 1137
            G+ G  C
Sbjct: 330  GYTGAQC 336



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 84/304 (27%), Positives = 124/304 (40%), Gaps = 51/304 (16%)

Query: 870  VAEEMTHNC-PNGCSGKGEC----LMGHCQCQPGFGG-------DDCSKSVCP--VLCSQ 915
            + E    +C  N C   G C    +   C C  G+ G       D+C+ S C    +C Q
Sbjct: 106  ICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-Q 164

Query: 916  RGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCG 970
             G  I+G  C C PG++G+ C L  DEC    C     C+N  G+  C C   Y G  C 
Sbjct: 165  DG--IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 222

Query: 971  -EID-CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD 1024
             EID C    C     C +      C C  G+ G  C  ++ D  +C      HG   VD
Sbjct: 223  LEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHC-ELNTD--ECASQPCLHGGLCVD 279

Query: 1025 TQ---TCSCHAK-WSGEDCS--KEVC-SLECGPHGRCVGE----SCSCAAGWSGEFCSVR 1073
             +   +C+C    ++G  C     +C S  C  +  C       +C C  G++G  C + 
Sbjct: 280  GENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEID 339

Query: 1074 LCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD 1133
            L +  C  +    NG C+ +S    ++  + G P S + H     +  G + C C  G+ 
Sbjct: 340  LNE--CNSNPCQSNGECVELSS-EKQYGRITGLPSSFSYH-----EASG-YVCICQPGFT 390

Query: 1134 GPDC 1137
            G  C
Sbjct: 391  GIHC 394



 Score = 70.5 bits (165), Expect = 8e-11
 Identities = 61/234 (26%), Positives = 89/234 (38%), Gaps = 40/234 (17%)

Query: 850  WFLSLYNDDGDPQEISFVALVAEEMTHNC-------PNGCSGKGEC----LMGHCQCQPG 898
            +F +++     PQE  F+ +    +   C        N C   G C       HC C  G
Sbjct: 1109 YFENVHGFINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLG 1168

Query: 899  FGGDDCSKSV--C---PVLCSQRGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            + G  C  ++  C   P +     + +    C C PG+ G  C +  D C+   C     
Sbjct: 1169 WSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGAT 1228

Query: 953  CV---NG-KCSCVRGYKGKFCGEIDCPHP---------TCSGHGFCIEGT----CVCKKG 995
            C+   NG  C C   + GKFC +   P           TC   G C E      C+C+ G
Sbjct: 1229 CISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPG 1288

Query: 996  WKGADCGTMDKDALQCLPDCSGHGTFDVDTQT---CSCHAKWSGEDCSKEVCSL 1046
            + G  C   +KD  +C  D   +G    D      C C   ++GE C  +V SL
Sbjct: 1289 FTGEWC---EKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDVSSL 1339



 Score = 65.7 bits (153), Expect = 2e-09
 Identities = 53/179 (29%), Positives = 73/179 (40%), Gaps = 27/179 (15%)

Query: 919  YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID- 973
            Y +  C C  GW GK C L  DEC    C  HG+C +      C+C  GY G  C E+D 
Sbjct: 1158 YSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCTCEPGYTGVNC-EVDI 1215

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC------LPDCSGHGTF 1021
              C    C+    CI  T    C+C   + G  C      +  C      L   +G    
Sbjct: 1216 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1275

Query: 1022 DVDTQ-TCSCHAKWSGEDCSKEV--CSLE-CGPHGRCVG----ESCSCAAGWSGEFCSV 1072
            +  T+  C C   ++GE C K++  C+ + C   G C        C C   ++GE C V
Sbjct: 1276 EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 67/254 (26%), Positives = 96/254 (37%), Gaps = 63/254 (24%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--CPVL-CSQRGEYINGE----CQCN-PG 929
            C NG + +       C C PGF GD C  +   C    C   G  ++GE    C C   G
Sbjct: 233  CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSG 292

Query: 930  WKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEID---CPHPTCSGH 982
            + G  C      C    C+ +  C     N  C C  GY G  C EID   C    C  +
Sbjct: 293  FTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQC-EIDLNECNSNPCQSN 351

Query: 983  GFCIEGT------------------------CVCKKGWKGADCGTMDKDALQCLPD-CSG 1017
            G C+E +                        C+C+ G+ G  C   ++D  +C  + C  
Sbjct: 352  GECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC---EEDVNECSSNPCQN 408

Query: 1018 HGTFD--VDTQTCSC------HAKWSGEDCSKEV--CS-LECGPHGRCV--------GES 1058
             GT +      TC C         + G DCS  +  C+  +C  +G C+        G S
Sbjct: 409  GGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFS 468

Query: 1059 CSCAAGWSGEFCSV 1072
            C C +G++G  C +
Sbjct: 469  CLCPSGYTGSLCEI 482



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 1059 CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT----CLCVSGWNGRHC--TLEGCPRSC 1110
            CSC  GWSG+ C + +  C +    HG C +      C C  G+ G +C   ++ C    
Sbjct: 1163 CSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ 1222

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC--TTLKEQICDDSRDN 1151
              +G   + +   + C CF  + G  C  + L   +C + + N
Sbjct: 1223 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1265


>AB208923-1|BAD92160.1|  441|Homo sapiens crumbs homolog 1 isoform II
            precursor variant protein.
          Length = 441

 Score = 96.3 bits (229), Expect = 1e-18
 Identities = 85/307 (27%), Positives = 122/307 (39%), Gaps = 48/307 (15%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGG--DDCSKSVCPVL---CSQRGEYIN--GE--- 923
            ++++C N  + K       C C         DC     P     C      +N  GE   
Sbjct: 60   LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 119

Query: 924  -CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEID---CP 975
             C+C PG+ G  C      C    C   G C    +   C C  GY G+FC EID   C 
Sbjct: 120  LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-EIDHDECA 178

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTC 1028
               C     C +G    +C C  G++G  C   D +  +C  D C    T   ++   TC
Sbjct: 179  SSPCQNGAVCQDGIDGYSCFCVPGYQGRHC---DLEVDECASDPCKNEATCLNEIGRYTC 235

Query: 1029 SCHAKWSGEDCSKEV--C-SLECGPHGRC---VGE-SCSCAAGWSGEFCSVRL--CDAR- 1078
             C   +SG +C  E+  C S  C     C   +G   C CA G+ G+ C +    C ++ 
Sbjct: 236  ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQP 295

Query: 1079 CAEHGQCKNG----TCLCV-SGWNGRHC--TLEGC-PRSCAGHGQCRVDNDGRWECKCFD 1130
            C   G C +G    +C C  SG+ G HC   +  C  + C  +  C  D+   + C C+ 
Sbjct: 296  CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCE-DSVDNYTCHCWP 354

Query: 1131 GWDGPDC 1137
            G+ G  C
Sbjct: 355  GYTGAQC 361



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 78/280 (27%), Positives = 115/280 (41%), Gaps = 45/280 (16%)

Query: 870  VAEEMTHNC-PNGCSGKGEC----LMGHCQCQPGFGG-------DDCSKSVCP--VLCSQ 915
            + E    +C  N C   G C    +   C C  G+ G       D+C+ S C    +C Q
Sbjct: 131  ICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-Q 189

Query: 916  RGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFCG 970
             G  I+G  C C PG++G+ C L  DEC    C     C+N  G+  C C   Y G  C 
Sbjct: 190  DG--IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCE 247

Query: 971  -EID-CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD 1024
             EID C    C     C +      C C  G+ G  C  ++ D  +C      HG   VD
Sbjct: 248  LEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHC-ELNTD--ECASQPCLHGGLCVD 304

Query: 1025 TQ---TCSCHAK-WSGEDCS--KEVC-SLECGPHGRCVGE----SCSCAAGWSGEFCSVR 1073
             +   +C+C    ++G  C     +C S  C  +  C       +C C  G++G  C + 
Sbjct: 305  GENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEID 364

Query: 1074 LCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGH 1113
            L +  C  +    NG C+ +S    ++  + G P S + H
Sbjct: 365  LNE--CNSNPCQSNGECVELSS-EKQYGRITGLPSSFSYH 401


>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
          Length = 1534

 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 74/240 (30%), Positives = 103/240 (42%), Gaps = 40/240 (16%)

Query: 940  DECEVPDCNGHGHCVNG-----KCSCVRGYKGKFCGEID---CPHPTCSGHGFCI--EG- 988
            D C    C   G C N      +C+C  GYKG+ C E+    C    C   G C   EG 
Sbjct: 927  DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDC-EVSLNSCSSGPCENGGTCHAQEGE 985

Query: 989  ----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK--E 1042
                TC C  G++G  CG    D +       G     V   TC C  ++ G+ C +  +
Sbjct: 986  DAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVD 1045

Query: 1043 VCSLECGP---HGRCVGES----CSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG---- 1088
            +CS +  P     +CVG      C C  G++G+ CS     C D RC    QC +     
Sbjct: 1046 LCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSY 1105

Query: 1089 TCLCVSGWNGRHCTLEG---CPRS-CAG----HGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
            +CLC  G++G+ C +      P+S C G    +G   VD   R  C+C  G+ GP+C  L
Sbjct: 1106 SCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKL 1165



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 58/196 (29%), Positives = 78/196 (39%), Gaps = 28/196 (14%)

Query: 1011 CLPD-CSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSLECGP---HGRC---VGE--- 1057
            CL   C   GT   D      C+C + + G DC   + S   GP    G C    GE   
Sbjct: 929  CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLNSCSSGPCENGGTCHAQEGEDAP 988

Query: 1058 -SCSCAAGWSGEFCSVRL--C-DARCAEHGQCKNG----TCLCVSGWNGRHCT--LEGCP 1107
             +CSC  G+ G  C V    C D  CA  G C +G    TC C   + G+ C   ++ C 
Sbjct: 989  FTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCS 1048

Query: 1108 ---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                 C    QC    DG   C+C  G+ G +C+  ++  C D R  +    +D  +   
Sbjct: 1049 PDLNPCQHEAQCVGTPDGP-RCECMPGYAGDNCSENQDD-CRDHRCQNGAQCMDEVNSYS 1106

Query: 1165 CQSPACKSSQLCVSSP 1180
            C      S QLC   P
Sbjct: 1107 CLCAEGYSGQLCEIPP 1122



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 40/125 (32%), Positives = 45/125 (36%), Gaps = 18/125 (14%)

Query: 894  QCQPGF--GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD-ECEVPDCNGH 950
            Q +PG   G + C K  C     Q        C C  GW G  C    D  C    C  H
Sbjct: 1330 QMKPGVVPGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKC-VH 1388

Query: 951  GHCV-----NGKCSCVRGYKGKFCGEIDCPHPTCSG----HGFC-IEGT----CVCKKGW 996
            G CV     +  C C  GY G  C +       C G    HG C   GT    CVC  G+
Sbjct: 1389 GQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGF 1448

Query: 997  KGADC 1001
             G  C
Sbjct: 1449 SGELC 1453



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 39/128 (30%), Positives = 46/128 (35%), Gaps = 15/128 (11%)

Query: 1037 EDCSKEVCSLE-CGPHGRCVGESCSCAAGWSGEFCSVRL---CDARCAEHGQC-----KN 1087
            E C K  C    C P+    G  C C AGW G  C       C      HGQC      +
Sbjct: 1340 EPCRKLYCLHGICQPNAT-PGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALS 1398

Query: 1088 GTCLCVSGWNGRHCTLEGC-PRSCAG----HGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
             +C C  G++G  C   G     C G    HG C+        C C  G+ G  C    E
Sbjct: 1399 YSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESE 1458

Query: 1143 QICDDSRD 1150
               D  RD
Sbjct: 1459 CRGDPVRD 1466



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 36/126 (28%), Positives = 47/126 (37%), Gaps = 17/126 (13%)

Query: 1074 LC-DARCAEHGQCKNGT-----CLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDN--DG 1122
            LC  + C   G C N       C C SG+ GR C  +L  C    C   G C      D 
Sbjct: 928  LCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLNSCSSGPCENGGTCHAQEGEDA 987

Query: 1123 RWECKCFDGWDGPDCTTLKEQICDDSRDN-----DKDGLVDCEDPECCQSPACKS-SQLC 1176
             + C C  G++GP C    +   D +  N     D  G   C+ P   +  AC+    LC
Sbjct: 988  PFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLC 1047

Query: 1177 VSSPKP 1182
                 P
Sbjct: 1048 SPDLNP 1053



 Score = 35.5 bits (78), Expect = 2.9
 Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 15/120 (12%)

Query: 876  HNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ---------- 925
            H C +G     + L   CQCQ G+ G  C+++       +  + ++G CQ          
Sbjct: 1384 HKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCV 1443

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
            C+PG+ G+ C  +  EC             G   C      +    ++C   +C G G C
Sbjct: 1444 CDPGFSGELCE-QESECRGDPVRDFHQVQRGYAIC---QTTRPLSWVEC-RGSCPGQGCC 1498


>AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2
            precursor protein.
          Length = 1285

 Score = 93.1 bits (221), Expect = 1e-17
 Identities = 80/288 (27%), Positives = 113/288 (39%), Gaps = 37/288 (12%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV---CPVLCSQRGEYING----ECQCNPGW 930
            C +G + +       C C  G+ G  C   V       C   G  ++G     C C PG+
Sbjct: 117  CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY 176

Query: 931  KGKECSLRHDECEVPDCNGHGHC---VNG-KCSCV-RGYKGKFCGE--IDCPHPTCSGHG 983
             G  C L  DEC+   C   G C   VNG +C C   GY+G  C    ++C    C  + 
Sbjct: 177  GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNA 236

Query: 984  FCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
             C+EG     C+C  G+ G  C  +D+D  +C      HG   +     S  A + G   
Sbjct: 237  SCLEGLGSFRCLCWPGYSGELC-EVDED--ECASSPCQHGGRCLQR---SDPALYGGVQA 290

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCK---NG-TCLC 1092
            +               G  C C  G+ G  C V +  C +R C   G C+   NG  C C
Sbjct: 291  AFPGAF----SFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHC 346

Query: 1093 VSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
              G+ G  C   ++ C      HG    D    + C+C + W G DC+
Sbjct: 347  PDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCS 394



 Score = 91.9 bits (218), Expect = 3e-17
 Identities = 83/293 (28%), Positives = 115/293 (39%), Gaps = 40/293 (13%)

Query: 875  THNCPNG--CSGKGECLMG-HCQCQPGFGG-------DDCSKSVCPVLCSQRGEYINGEC 924
            T  C +G  C  +G    G  C C PGF G       D+C+   C    + R      EC
Sbjct: 73   TQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYEC 132

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EID-CPHPT 978
             C  G+ G  C +  DEC    C   G C++G    +C C  GY G  C  ++D C    
Sbjct: 133  HCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP 192

Query: 979  CSGHGFC---IEG-TCVCK-KGWKGADCGTMDKDALQCLPDCSGHGTFDVD---TQTCSC 1030
            C+  G C   + G  C C   G++G  C   +++ L+C      H    ++   +  C C
Sbjct: 193  CAHGGTCHDLVNGFRCDCAGTGYEGTHC---EREVLECASAPCEHNASCLEGLGSFRCLC 249

Query: 1031 HAKWSGEDC---SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKN 1087
               +SGE C     E  S  C   GRC+  S     G       V+              
Sbjct: 250  WPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYG------GVQAAFPGAFSFRHAAG 303

Query: 1088 GTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C C  G+ G  C +E   C  R C   G C+ D    ++C C DG+ GP C
Sbjct: 304  FLCHCPPGFEGADCGVEVDECASRPCLNGGHCQ-DLPNGFQCHCPDGYAGPTC 355



 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 80/301 (26%), Positives = 114/301 (37%), Gaps = 56/301 (18%)

Query: 864  ISFVALVAEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVL-CSQ 915
            + +  +  E     C +  C   G CL G     C C PG+GG  C   +  C    C+ 
Sbjct: 136  LGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH 195

Query: 916  RG---EYING-ECQC-NPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKG 966
             G   + +NG  C C   G++G  C     EC    C  +  C+ G    +C C  GY G
Sbjct: 196  GGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSG 255

Query: 967  KFC--GEIDCPHPTCSGHGFCIEGT-------------------------CVCKKGWKGA 999
            + C   E +C    C   G C++ +                         C C  G++GA
Sbjct: 256  ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCSKEV--C-SLECGPHGRC- 1054
            DCG ++ D     P  +G    D+     C C   ++G  C ++V  C S  C   G C 
Sbjct: 316  DCG-VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCS 374

Query: 1055 ---VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCA 1111
                G  C C   W G  CSV+L    C  H      TC+ +   +G H  +  CP    
Sbjct: 375  DTVAGYICRCPETWGGRDCSVQL--TGCQGHTCPLAATCIPIFE-SGVHSYVCHCPPGTH 431

Query: 1112 G 1112
            G
Sbjct: 432  G 432



 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 47/170 (27%), Positives = 66/170 (38%), Gaps = 17/170 (10%)

Query: 900  GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG 956
            G   C+ S C    + R  +    C C PGW+G  C    D C    C   G C    +G
Sbjct: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPC-ARGRCHTHPDG 1114

Query: 957  K--CSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPD 1014
            +  C C  G+ G  C  +  P   CS +  C++G+  C+ G   A+C         CL  
Sbjct: 1115 RFECRCPPGFGGPRC-RLPVPSKECSLNVTCLDGS-PCEGGSPAANC--------SCLEG 1164

Query: 1015 CSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAG 1064
             +G     V T  C  +   +G  C       EC  + R  G+ C  A G
Sbjct: 1165 LAGQ-RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKG 1213



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 6/65 (9%)

Query: 1079 CAEHGQCKN----GTCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
            C   G C++      C C  GW G  C   ++ C  +    G+C    DGR+EC+C  G+
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124

Query: 1133 DGPDC 1137
             GP C
Sbjct: 1125 GGPRC 1129



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 38/129 (29%), Positives = 49/129 (37%), Gaps = 20/129 (15%)

Query: 893  CQCQPGFGGDDCSKSV--CPVLCSQRGE---YING--ECQCNPGWKGKECSL--RHDECE 943
            C C PG+ G  C   V  C      RG    + +G  EC+C PG+ G  C L     EC 
Sbjct: 1080 CACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECS 1139

Query: 944  V-PDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE----GTCVC 992
            +   C     C  G     CSC+ G  G+ C    + C    C   G C        C+C
Sbjct: 1140 LNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECIC 1199

Query: 993  KKGWKGADC 1001
               + G  C
Sbjct: 1200 NARFSGQFC 1208



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 15/94 (15%)

Query: 893 CQCQPGFGGDDCSKSVCPVL---CSQRG---EYINGE-CQCNPGWKGKECSLRHDECEVP 945
           C C  G+ G  C + V   L   C   G   + + G  C+C   W G++CS++   C+  
Sbjct: 344 CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403

Query: 946 DCNGHGHCV--------NGKCSCVRGYKGKFCGE 971
            C     C+        +  C C  G  G FCG+
Sbjct: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 23/92 (25%), Positives = 35/92 (38%), Gaps = 12/92 (13%)

Query: 1058 SCSCAAGWSGEFCSVRL--CDARCAEHGQCKNG-----TCLCVSGWNGRHCTLEGCPRSC 1110
            +C+C  GW G  C   +  C +     G+C         C C  G+ G  C L    + C
Sbjct: 1079 ACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKEC 1138

Query: 1111 AGHGQCRVDN--DG---RWECKCFDGWDGPDC 1137
            + +  C   +  +G      C C +G  G  C
Sbjct: 1139 SLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC 1170


>AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2
            (Drosophila) protein.
          Length = 1285

 Score = 93.1 bits (221), Expect = 1e-17
 Identities = 80/288 (27%), Positives = 113/288 (39%), Gaps = 37/288 (12%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV---CPVLCSQRGEYING----ECQCNPGW 930
            C +G + +       C C  G+ G  C   V       C   G  ++G     C C PG+
Sbjct: 117  CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY 176

Query: 931  KGKECSLRHDECEVPDCNGHGHC---VNG-KCSCV-RGYKGKFCGE--IDCPHPTCSGHG 983
             G  C L  DEC+   C   G C   VNG +C C   GY+G  C    ++C    C  + 
Sbjct: 177  GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNA 236

Query: 984  FCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
             C+EG     C+C  G+ G  C  +D+D  +C      HG   +     S  A + G   
Sbjct: 237  SCLEGLGSFRCLCWPGYSGELC-EVDED--ECASSPCQHGGRCLQR---SDPALYGGVQA 290

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCK---NG-TCLC 1092
            +               G  C C  G+ G  C V +  C +R C   G C+   NG  C C
Sbjct: 291  AFPGAF----SFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHC 346

Query: 1093 VSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
              G+ G  C   ++ C      HG    D    + C+C + W G DC+
Sbjct: 347  PDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCS 394



 Score = 91.9 bits (218), Expect = 3e-17
 Identities = 83/293 (28%), Positives = 115/293 (39%), Gaps = 40/293 (13%)

Query: 875  THNCPNG--CSGKGECLMG-HCQCQPGFGG-------DDCSKSVCPVLCSQRGEYINGEC 924
            T  C +G  C  +G    G  C C PGF G       D+C+   C    + R      EC
Sbjct: 73   TQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYEC 132

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EID-CPHPT 978
             C  G+ G  C +  DEC    C   G C++G    +C C  GY G  C  ++D C    
Sbjct: 133  HCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP 192

Query: 979  CSGHGFC---IEG-TCVCK-KGWKGADCGTMDKDALQCLPDCSGHGTFDVD---TQTCSC 1030
            C+  G C   + G  C C   G++G  C   +++ L+C      H    ++   +  C C
Sbjct: 193  CAHGGTCHDLVNGFRCDCAGTGYEGTHC---EREVLECASAPCEHNASCLEGLGSFRCLC 249

Query: 1031 HAKWSGEDC---SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKN 1087
               +SGE C     E  S  C   GRC+  S     G       V+              
Sbjct: 250  WPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYG------GVQAAFPGAFSFRHAAG 303

Query: 1088 GTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C C  G+ G  C +E   C  R C   G C+ D    ++C C DG+ GP C
Sbjct: 304  FLCHCPPGFEGADCGVEVDECASRPCLNGGHCQ-DLPNGFQCHCPDGYAGPTC 355



 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 80/301 (26%), Positives = 114/301 (37%), Gaps = 56/301 (18%)

Query: 864  ISFVALVAEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVL-CSQ 915
            + +  +  E     C +  C   G CL G     C C PG+GG  C   +  C    C+ 
Sbjct: 136  LGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH 195

Query: 916  RG---EYING-ECQC-NPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKG 966
             G   + +NG  C C   G++G  C     EC    C  +  C+ G    +C C  GY G
Sbjct: 196  GGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSG 255

Query: 967  KFC--GEIDCPHPTCSGHGFCIEGT-------------------------CVCKKGWKGA 999
            + C   E +C    C   G C++ +                         C C  G++GA
Sbjct: 256  ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCSKEV--C-SLECGPHGRC- 1054
            DCG ++ D     P  +G    D+     C C   ++G  C ++V  C S  C   G C 
Sbjct: 316  DCG-VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCS 374

Query: 1055 ---VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCA 1111
                G  C C   W G  CSV+L    C  H      TC+ +   +G H  +  CP    
Sbjct: 375  DTVAGYICRCPETWGGRDCSVQL--TGCQGHTCPLAATCIPIFE-SGVHSYVCHCPPGTH 431

Query: 1112 G 1112
            G
Sbjct: 432  G 432



 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 47/170 (27%), Positives = 66/170 (38%), Gaps = 17/170 (10%)

Query: 900  GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG 956
            G   C+ S C    + R  +    C C PGW+G  C    D C    C   G C    +G
Sbjct: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPC-ARGRCHTHPDG 1114

Query: 957  K--CSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPD 1014
            +  C C  G+ G  C  +  P   CS +  C++G+  C+ G   A+C         CL  
Sbjct: 1115 RFECRCPPGFGGPRC-RLPVPSKECSLNVTCLDGS-PCEGGSPAANC--------SCLEG 1164

Query: 1015 CSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAG 1064
             +G     V T  C  +   +G  C       EC  + R  G+ C  A G
Sbjct: 1165 LAGQ-RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKG 1213



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 6/65 (9%)

Query: 1079 CAEHGQCKN----GTCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
            C   G C++      C C  GW G  C   ++ C  +    G+C    DGR+EC+C  G+
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124

Query: 1133 DGPDC 1137
             GP C
Sbjct: 1125 GGPRC 1129



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 38/129 (29%), Positives = 49/129 (37%), Gaps = 20/129 (15%)

Query: 893  CQCQPGFGGDDCSKSV--CPVLCSQRGE---YING--ECQCNPGWKGKECSL--RHDECE 943
            C C PG+ G  C   V  C      RG    + +G  EC+C PG+ G  C L     EC 
Sbjct: 1080 CACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECS 1139

Query: 944  V-PDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE----GTCVC 992
            +   C     C  G     CSC+ G  G+ C    + C    C   G C        C+C
Sbjct: 1140 LNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECIC 1199

Query: 993  KKGWKGADC 1001
               + G  C
Sbjct: 1200 NARFSGQFC 1208



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 15/94 (15%)

Query: 893 CQCQPGFGGDDCSKSVCPVL---CSQRG---EYINGE-CQCNPGWKGKECSLRHDECEVP 945
           C C  G+ G  C + V   L   C   G   + + G  C+C   W G++CS++   C+  
Sbjct: 344 CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403

Query: 946 DCNGHGHCV--------NGKCSCVRGYKGKFCGE 971
            C     C+        +  C C  G  G FCG+
Sbjct: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 23/92 (25%), Positives = 35/92 (38%), Gaps = 12/92 (13%)

Query: 1058 SCSCAAGWSGEFCSVRL--CDARCAEHGQCKNG-----TCLCVSGWNGRHCTLEGCPRSC 1110
            +C+C  GW G  C   +  C +     G+C         C C  G+ G  C L    + C
Sbjct: 1079 ACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKEC 1138

Query: 1111 AGHGQCRVDN--DG---RWECKCFDGWDGPDC 1137
            + +  C   +  +G      C C +G  G  C
Sbjct: 1139 SLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC 1170


>AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2
            (Drosophila) protein.
          Length = 1176

 Score = 93.1 bits (221), Expect = 1e-17
 Identities = 80/288 (27%), Positives = 113/288 (39%), Gaps = 37/288 (12%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV---CPVLCSQRGEYING----ECQCNPGW 930
            C +G + +       C C  G+ G  C   V       C   G  ++G     C C PG+
Sbjct: 117  CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY 176

Query: 931  KGKECSLRHDECEVPDCNGHGHC---VNG-KCSCV-RGYKGKFCGE--IDCPHPTCSGHG 983
             G  C L  DEC+   C   G C   VNG +C C   GY+G  C    ++C    C  + 
Sbjct: 177  GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNA 236

Query: 984  FCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
             C+EG     C+C  G+ G  C  +D+D  +C      HG   +     S  A + G   
Sbjct: 237  SCLEGLGSFRCLCWPGYSGELC-EVDED--ECASSPCQHGGRCLQR---SDPALYGGVQA 290

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCK---NG-TCLC 1092
            +               G  C C  G+ G  C V +  C +R C   G C+   NG  C C
Sbjct: 291  AFPGAF----SFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHC 346

Query: 1093 VSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
              G+ G  C   ++ C      HG    D    + C+C + W G DC+
Sbjct: 347  PDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCS 394



 Score = 91.9 bits (218), Expect = 3e-17
 Identities = 83/293 (28%), Positives = 115/293 (39%), Gaps = 40/293 (13%)

Query: 875  THNCPNG--CSGKGECLMG-HCQCQPGFGG-------DDCSKSVCPVLCSQRGEYINGEC 924
            T  C +G  C  +G    G  C C PGF G       D+C+   C    + R      EC
Sbjct: 73   TQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYEC 132

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EID-CPHPT 978
             C  G+ G  C +  DEC    C   G C++G    +C C  GY G  C  ++D C    
Sbjct: 133  HCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP 192

Query: 979  CSGHGFC---IEG-TCVCK-KGWKGADCGTMDKDALQCLPDCSGHGTFDVD---TQTCSC 1030
            C+  G C   + G  C C   G++G  C   +++ L+C      H    ++   +  C C
Sbjct: 193  CAHGGTCHDLVNGFRCDCAGTGYEGTHC---EREVLECASAPCEHNASCLEGLGSFRCLC 249

Query: 1031 HAKWSGEDC---SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKN 1087
               +SGE C     E  S  C   GRC+  S     G       V+              
Sbjct: 250  WPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYG------GVQAAFPGAFSFRHAAG 303

Query: 1088 GTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C C  G+ G  C +E   C  R C   G C+ D    ++C C DG+ GP C
Sbjct: 304  FLCHCPPGFEGADCGVEVDECASRPCLNGGHCQ-DLPNGFQCHCPDGYAGPTC 355



 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 80/301 (26%), Positives = 114/301 (37%), Gaps = 56/301 (18%)

Query: 864  ISFVALVAEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVL-CSQ 915
            + +  +  E     C +  C   G CL G     C C PG+GG  C   +  C    C+ 
Sbjct: 136  LGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH 195

Query: 916  RG---EYING-ECQC-NPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKG 966
             G   + +NG  C C   G++G  C     EC    C  +  C+ G    +C C  GY G
Sbjct: 196  GGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSG 255

Query: 967  KFC--GEIDCPHPTCSGHGFCIEGT-------------------------CVCKKGWKGA 999
            + C   E +C    C   G C++ +                         C C  G++GA
Sbjct: 256  ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCSKEV--C-SLECGPHGRC- 1054
            DCG ++ D     P  +G    D+     C C   ++G  C ++V  C S  C   G C 
Sbjct: 316  DCG-VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCS 374

Query: 1055 ---VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCA 1111
                G  C C   W G  CSV+L    C  H      TC+ +   +G H  +  CP    
Sbjct: 375  DTVAGYICRCPETWGGRDCSVQL--TGCQGHTCPLAATCIPIFE-SGVHSYVCHCPPGTH 431

Query: 1112 G 1112
            G
Sbjct: 432  G 432



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 6/65 (9%)

Query: 1079 CAEHGQCKN----GTCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
            C   G C++      C C  GW G  C   ++ C  +    G+C    DGR+EC+C  G+
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124

Query: 1133 DGPDC 1137
             GP C
Sbjct: 1125 GGPRC 1129



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 15/94 (15%)

Query: 893 CQCQPGFGGDDCSKSVCPVL---CSQRG---EYINGE-CQCNPGWKGKECSLRHDECEVP 945
           C C  G+ G  C + V   L   C   G   + + G  C+C   W G++CS++   C+  
Sbjct: 344 CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403

Query: 946 DCNGHGHCV--------NGKCSCVRGYKGKFCGE 971
            C     C+        +  C C  G  G FCG+
Sbjct: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437



 Score = 39.1 bits (87), Expect = 0.24
 Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 6/75 (8%)

Query: 900  GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG 956
            G   C+ S C    + R  +    C C PGW+G  C    D C    C   G C    +G
Sbjct: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPC-ARGRCHTHPDG 1114

Query: 957  K--CSCVRGYKGKFC 969
            +  C C  G+ G  C
Sbjct: 1115 RFECRCPPGFGGPRC 1129


>AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2
            (Drosophila) protein.
          Length = 1285

 Score = 93.1 bits (221), Expect = 1e-17
 Identities = 80/288 (27%), Positives = 113/288 (39%), Gaps = 37/288 (12%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV---CPVLCSQRGEYING----ECQCNPGW 930
            C +G + +       C C  G+ G  C   V       C   G  ++G     C C PG+
Sbjct: 117  CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY 176

Query: 931  KGKECSLRHDECEVPDCNGHGHC---VNG-KCSCV-RGYKGKFCGE--IDCPHPTCSGHG 983
             G  C L  DEC+   C   G C   VNG +C C   GY+G  C    ++C    C  + 
Sbjct: 177  GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNA 236

Query: 984  FCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
             C+EG     C+C  G+ G  C  +D+D  +C      HG   +     S  A + G   
Sbjct: 237  SCLEGLGSFRCLCWPGYSGELC-EVDED--ECASSPCQHGGRCLQR---SDPALYGGVQA 290

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCK---NG-TCLC 1092
            +               G  C C  G+ G  C V +  C +R C   G C+   NG  C C
Sbjct: 291  AFPGAF----SFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHC 346

Query: 1093 VSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
              G+ G  C   ++ C      HG    D    + C+C + W G DC+
Sbjct: 347  PDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCS 394



 Score = 91.9 bits (218), Expect = 3e-17
 Identities = 83/293 (28%), Positives = 115/293 (39%), Gaps = 40/293 (13%)

Query: 875  THNCPNG--CSGKGECLMG-HCQCQPGFGG-------DDCSKSVCPVLCSQRGEYINGEC 924
            T  C +G  C  +G    G  C C PGF G       D+C+   C    + R      EC
Sbjct: 73   TQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYEC 132

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EID-CPHPT 978
             C  G+ G  C +  DEC    C   G C++G    +C C  GY G  C  ++D C    
Sbjct: 133  HCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP 192

Query: 979  CSGHGFC---IEG-TCVCK-KGWKGADCGTMDKDALQCLPDCSGHGTFDVD---TQTCSC 1030
            C+  G C   + G  C C   G++G  C   +++ L+C      H    ++   +  C C
Sbjct: 193  CAHGGTCHDLVNGFRCDCAGTGYEGTHC---EREVLECASAPCEHNASCLEGLGSFRCLC 249

Query: 1031 HAKWSGEDC---SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKN 1087
               +SGE C     E  S  C   GRC+  S     G       V+              
Sbjct: 250  WPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYG------GVQAAFPGAFSFRHAAG 303

Query: 1088 GTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C C  G+ G  C +E   C  R C   G C+ D    ++C C DG+ GP C
Sbjct: 304  FLCHCPPGFEGADCGVEVDECASRPCLNGGHCQ-DLPNGFQCHCPDGYAGPTC 355



 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 80/301 (26%), Positives = 114/301 (37%), Gaps = 56/301 (18%)

Query: 864  ISFVALVAEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVL-CSQ 915
            + +  +  E     C +  C   G CL G     C C PG+GG  C   +  C    C+ 
Sbjct: 136  LGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH 195

Query: 916  RG---EYING-ECQC-NPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKG 966
             G   + +NG  C C   G++G  C     EC    C  +  C+ G    +C C  GY G
Sbjct: 196  GGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSG 255

Query: 967  KFC--GEIDCPHPTCSGHGFCIEGT-------------------------CVCKKGWKGA 999
            + C   E +C    C   G C++ +                         C C  G++GA
Sbjct: 256  ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCSKEV--C-SLECGPHGRC- 1054
            DCG ++ D     P  +G    D+     C C   ++G  C ++V  C S  C   G C 
Sbjct: 316  DCG-VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCS 374

Query: 1055 ---VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCA 1111
                G  C C   W G  CSV+L    C  H      TC+ +   +G H  +  CP    
Sbjct: 375  DTVAGYICRCPETWGGRDCSVQL--TGCQGHTCPLAATCIPIFE-SGVHSYVCHCPPGTH 431

Query: 1112 G 1112
            G
Sbjct: 432  G 432



 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 47/170 (27%), Positives = 66/170 (38%), Gaps = 17/170 (10%)

Query: 900  GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG 956
            G   C+ S C    + R  +    C C PGW+G  C    D C    C   G C    +G
Sbjct: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPC-ARGRCHTHPDG 1114

Query: 957  K--CSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPD 1014
            +  C C  G+ G  C  +  P   CS +  C++G+  C+ G   A+C         CL  
Sbjct: 1115 RFECRCPPGFGGPRC-RLPVPSKECSLNVTCLDGS-PCEGGSPAANC--------SCLEG 1164

Query: 1015 CSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAG 1064
             +G     V T  C  +   +G  C       EC  + R  G+ C  A G
Sbjct: 1165 LAGQ-RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKG 1213



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 6/65 (9%)

Query: 1079 CAEHGQCKN----GTCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
            C   G C++      C C  GW G  C   ++ C  +    G+C    DGR+EC+C  G+
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124

Query: 1133 DGPDC 1137
             GP C
Sbjct: 1125 GGPRC 1129



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 38/129 (29%), Positives = 49/129 (37%), Gaps = 20/129 (15%)

Query: 893  CQCQPGFGGDDCSKSV--CPVLCSQRGE---YING--ECQCNPGWKGKECSL--RHDECE 943
            C C PG+ G  C   V  C      RG    + +G  EC+C PG+ G  C L     EC 
Sbjct: 1080 CACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECS 1139

Query: 944  V-PDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIE----GTCVC 992
            +   C     C  G     CSC+ G  G+ C    + C    C   G C        C+C
Sbjct: 1140 LNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECIC 1199

Query: 993  KKGWKGADC 1001
               + G  C
Sbjct: 1200 NARFSGQFC 1208



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 15/94 (15%)

Query: 893 CQCQPGFGGDDCSKSVCPVL---CSQRG---EYINGE-CQCNPGWKGKECSLRHDECEVP 945
           C C  G+ G  C + V   L   C   G   + + G  C+C   W G++CS++   C+  
Sbjct: 344 CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403

Query: 946 DCNGHGHCV--------NGKCSCVRGYKGKFCGE 971
            C     C+        +  C C  G  G FCG+
Sbjct: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437



 Score = 35.9 bits (79), Expect = 2.2
 Identities = 23/92 (25%), Positives = 35/92 (38%), Gaps = 12/92 (13%)

Query: 1058 SCSCAAGWSGEFCSVRL--CDARCAEHGQCKNG-----TCLCVSGWNGRHCTLEGCPRSC 1110
            +C+C  GW G  C   +  C +     G+C         C C  G+ G  C L    + C
Sbjct: 1079 ACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKEC 1138

Query: 1111 AGHGQCRVDN--DG---RWECKCFDGWDGPDC 1137
            + +  C   +  +G      C C +G  G  C
Sbjct: 1139 SLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC 1170


>AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2
            (Drosophila) protein.
          Length = 1176

 Score = 93.1 bits (221), Expect = 1e-17
 Identities = 80/288 (27%), Positives = 113/288 (39%), Gaps = 37/288 (12%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV---CPVLCSQRGEYING----ECQCNPGW 930
            C +G + +       C C  G+ G  C   V       C   G  ++G     C C PG+
Sbjct: 117  CHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGY 176

Query: 931  KGKECSLRHDECEVPDCNGHGHC---VNG-KCSCV-RGYKGKFCGE--IDCPHPTCSGHG 983
             G  C L  DEC+   C   G C   VNG +C C   GY+G  C    ++C    C  + 
Sbjct: 177  GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNA 236

Query: 984  FCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
             C+EG     C+C  G+ G  C  +D+D  +C      HG   +     S  A + G   
Sbjct: 237  SCLEGLGSFRCLCWPGYSGELC-EVDED--ECASSPCQHGGRCLQR---SDPALYGGVQA 290

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCK---NG-TCLC 1092
            +               G  C C  G+ G  C V +  C +R C   G C+   NG  C C
Sbjct: 291  AFPGAF----SFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHC 346

Query: 1093 VSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
              G+ G  C   ++ C      HG    D    + C+C + W G DC+
Sbjct: 347  PDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCS 394



 Score = 91.9 bits (218), Expect = 3e-17
 Identities = 83/293 (28%), Positives = 115/293 (39%), Gaps = 40/293 (13%)

Query: 875  THNCPNG--CSGKGECLMG-HCQCQPGFGG-------DDCSKSVCPVLCSQRGEYINGEC 924
            T  C +G  C  +G    G  C C PGF G       D+C+   C    + R      EC
Sbjct: 73   TQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYEC 132

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCG-EID-CPHPT 978
             C  G+ G  C +  DEC    C   G C++G    +C C  GY G  C  ++D C    
Sbjct: 133  HCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP 192

Query: 979  CSGHGFC---IEG-TCVCK-KGWKGADCGTMDKDALQCLPDCSGHGTFDVD---TQTCSC 1030
            C+  G C   + G  C C   G++G  C   +++ L+C      H    ++   +  C C
Sbjct: 193  CAHGGTCHDLVNGFRCDCAGTGYEGTHC---EREVLECASAPCEHNASCLEGLGSFRCLC 249

Query: 1031 HAKWSGEDC---SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKN 1087
               +SGE C     E  S  C   GRC+  S     G       V+              
Sbjct: 250  WPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYG------GVQAAFPGAFSFRHAAG 303

Query: 1088 GTCLCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C C  G+ G  C +E   C  R C   G C+ D    ++C C DG+ GP C
Sbjct: 304  FLCHCPPGFEGADCGVEVDECASRPCLNGGHCQ-DLPNGFQCHCPDGYAGPTC 355



 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 80/301 (26%), Positives = 114/301 (37%), Gaps = 56/301 (18%)

Query: 864  ISFVALVAEEMTHNCPNG-CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVL-CSQ 915
            + +  +  E     C +  C   G CL G     C C PG+GG  C   +  C    C+ 
Sbjct: 136  LGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH 195

Query: 916  RG---EYING-ECQC-NPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKG 966
             G   + +NG  C C   G++G  C     EC    C  +  C+ G    +C C  GY G
Sbjct: 196  GGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSG 255

Query: 967  KFC--GEIDCPHPTCSGHGFCIEGT-------------------------CVCKKGWKGA 999
            + C   E +C    C   G C++ +                         C C  G++GA
Sbjct: 256  ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCSKEV--C-SLECGPHGRC- 1054
            DCG ++ D     P  +G    D+     C C   ++G  C ++V  C S  C   G C 
Sbjct: 316  DCG-VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCS 374

Query: 1055 ---VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCA 1111
                G  C C   W G  CSV+L    C  H      TC+ +   +G H  +  CP    
Sbjct: 375  DTVAGYICRCPETWGGRDCSVQL--TGCQGHTCPLAATCIPIFE-SGVHSYVCHCPPGTH 431

Query: 1112 G 1112
            G
Sbjct: 432  G 432



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 6/65 (9%)

Query: 1079 CAEHGQCKN----GTCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
            C   G C++      C C  GW G  C   ++ C  +    G+C    DGR+EC+C  G+
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124

Query: 1133 DGPDC 1137
             GP C
Sbjct: 1125 GGPRC 1129



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 15/94 (15%)

Query: 893 CQCQPGFGGDDCSKSVCPVL---CSQRG---EYINGE-CQCNPGWKGKECSLRHDECEVP 945
           C C  G+ G  C + V   L   C   G   + + G  C+C   W G++CS++   C+  
Sbjct: 344 CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403

Query: 946 DCNGHGHCV--------NGKCSCVRGYKGKFCGE 971
            C     C+        +  C C  G  G FCG+
Sbjct: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437



 Score = 39.1 bits (87), Expect = 0.24
 Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 6/75 (8%)

Query: 900  GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG 956
            G   C+ S C    + R  +    C C PGW+G  C    D C    C   G C    +G
Sbjct: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPC-ARGRCHTHPDG 1114

Query: 957  K--CSCVRGYKGKFC 969
            +  C C  G+ G  C
Sbjct: 1115 RFECRCPPGFGGPRC 1129


>AB052950-1|BAC02696.1|  744|Homo sapiens SREC-5 protein.
          Length = 744

 Score = 93.1 bits (221), Expect = 1e-17
 Identities = 81/256 (31%), Positives = 106/256 (41%), Gaps = 55/256 (21%)

Query: 879  PNGCSGKGECLM-GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGEC----------QCN 927
            P+ C     C+  G C+C+PGF G  CS S CP      G+Y   +C          QC 
Sbjct: 60   PDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCP------GQYWGPDCRESCPCHPHGQCE 112

Query: 928  PGWKGKECSLRH--DECEVP-DCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHPTCSGH 982
            P     +C        CE P  C  HG C    G C C  G+    C    C   T +  
Sbjct: 113  PATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
                 G CVCK GW G  C      + +C  +C G    + D+  C+C   W G +C ++
Sbjct: 172  CEQATGACVCKPGWWGRRC------SFRC--NCHG-SPCEQDSGRCACRPGWWGPECQQQ 222

Query: 1043 VCSLECGPHGRCVGES--CSCAAGWSGEFCSVRLCDA-----RCAEH-GQCKN------- 1087
             C  EC   GRC   S  C+C  G+ G  C +  C A     +CA   G+CK+       
Sbjct: 223  -C--EC-VRGRCSAASGECTCPPGFRGARCELP-CPAGSHGVQCAHSCGRCKHNEPCSPD 277

Query: 1088 -GTC-LCVSGWNGRHC 1101
             G+C  C  GWNG  C
Sbjct: 278  TGSCESCEPGWNGTQC 293



 Score = 91.9 bits (218), Expect = 3e-17
 Identities = 70/234 (29%), Positives = 94/234 (40%), Gaps = 37/234 (15%)

Query: 955  NGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIE-------GTCVCKKGWKGADCGTM--- 1004
            + +  C  G++ K   + +C  P C G   C +       G C CK G+ GA C +    
Sbjct: 36   SAELQCCAGWRQK---DQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPG 92

Query: 1005 ---DKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES--C 1059
                 D  +  P C  HG  +  T  C C A   G  C    C+  CGPHGRC   +  C
Sbjct: 93   QYWGPDCRESCP-CHPHGQCEPATGACQCQADRWGARCEFP-CA--CGPHGRCDPATGVC 148

Query: 1060 SCAAGWSGEFCSVRLCDARCAEHGQCKN--GTCLCVSGWNGRHCTLEGCPRSCAGHGQCR 1117
             C  GW    C  R C    A   +C+   G C+C  GW GR C+       C  HG   
Sbjct: 149  HCEPGWWSSTCR-RPCQCNTAA-ARCEQATGACVCKPGWWGRRCSFR-----CNCHGSPC 201

Query: 1118 VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACK 1171
              + GR  C C  GW GP+C    +Q C+  R        +C  P   +   C+
Sbjct: 202  EQDSGR--CACRPGWWGPEC----QQQCECVRGRCSAASGECTCPPGFRGARCE 249



 Score = 88.6 bits (210), Expect = 3e-16
 Identities = 83/275 (30%), Positives = 110/275 (40%), Gaps = 52/275 (18%)

Query: 894  QCQPGFGGDD--CSKSVC--PVLCSQRGEYIN-GECQCNPGWKGKECSLR------HDEC 942
            QC  G+   D  C+  +C  P  C +    +  G C+C PG+ G  CS R        +C
Sbjct: 40   QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99

Query: 943  -EVPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFC--IEGTCVCKKGWK 997
             E   C+ HG C    G C C     G  C E  C    C  HG C    G C C+ GW 
Sbjct: 100  RESCPCHPHGQCEPATGACQCQADRWGARC-EFPC---ACGPHGRCDPATGVCHCEPGWW 155

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGR-CVG 1056
             + C    +   QC    +     +  T  C C   W G  CS       C  HG  C  
Sbjct: 156  SSTC----RRPCQCN---TAAARCEQATGACVCKPGWWGRRCS-----FRCNCHGSPCEQ 203

Query: 1057 ES--CSCAAGWSGEFCSVRLCDARCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPRSCAG 1112
            +S  C+C  GW G  C  + C+  C   G+C   +G C C  G+ G  C L  CP    G
Sbjct: 204  DSGRCACRPGWWGPECQQQ-CE--CVR-GRCSAASGECTCPPGFRGARCELP-CPAGSHG 258

Query: 1113 ----H--GQCRVD---NDGRWECK-CFDGWDGPDC 1137
                H  G+C+ +   +     C+ C  GW+G  C
Sbjct: 259  VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQC 293



 Score = 86.6 bits (205), Expect = 1e-15
 Identities = 64/207 (30%), Positives = 84/207 (40%), Gaps = 35/207 (16%)

Query: 879  PNGCSGKGEC--LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            P  C   G C    G C C+PG+    C +       + R E   G C C PGW G+ CS
Sbjct: 132  PCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191

Query: 937  LRHDECEVPDCNGHGH-CV--NGKCSCVRGYKGKFC-GEIDCPHPTCSGHGFCIEGTCVC 992
             R        CN HG  C   +G+C+C  G+ G  C  + +C    CS       G C C
Sbjct: 192  FR--------CNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCS----AASGECTC 239

Query: 993  KKGWKGADCG---TMDKDALQCLPD---CSGHGTFDVDTQTC-SCHAKWSGEDCSK---- 1041
              G++GA C          +QC      C  +     DT +C SC   W+G  C +    
Sbjct: 240  PPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLP 299

Query: 1042 ----EVCSLECGPHGRCVGESCSCAAG 1064
                E C  +C PH R  GE+C    G
Sbjct: 300  GTFGESCEQQC-PHCR-HGEACEPDTG 324


>AK123000-1|BAC85516.1| 1176|Homo sapiens  3 (HIVEP3).  protein.
          Length = 1176

 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 84/287 (29%), Positives = 110/287 (38%), Gaps = 55/287 (19%)

Query: 904  CSKSVCP--VLCSQRGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN----G 956
            C+   C    LC  +G   NG  C C PG++G  C L  DEC    C+    C N     
Sbjct: 71   CATQPCHHGALCVPQGPDPNGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRY 130

Query: 957  KCSCVRGYKGKFC-GEID-CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQ 1010
            +C C  GY G  C  E+D C    C     C++G     CVC  G+ G  C  +D D  Q
Sbjct: 131  ECHCPLGYAGVTCETEVDECASAPCLHGASCLDGVGSFRCVCAPGYGGTRC-QLDLDECQ 189

Query: 1011 CLPDCSGHGTFD-VDTQTCSCHAK-WSGEDCSKEV---CSLECGPHGRCV----GESCSC 1061
              P   G    D V+   C C    + G  C +EV    S  C  +  C+       C C
Sbjct: 190  SQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLC 249

Query: 1062 AAGWSGEFCSV---RLCDARCAEHGQCKNGT-------------------------CLCV 1093
              G+SGE C V       + C   G+C   +                         C C 
Sbjct: 250  WPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCP 309

Query: 1094 SGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             G+ G  C +E   C  R C   G C+ D    ++C C DG+ GP C
Sbjct: 310  PGFEGADCGVEVDECASRPCLNGGHCQ-DLPNGFQCHCPDGYAGPTC 355



 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 79/288 (27%), Positives = 112/288 (38%), Gaps = 37/288 (12%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSV---CPVLCSQRGEYING----ECQCNPGW 930
            C +G + +       C C  G+ G  C   V       C      ++G     C C PG+
Sbjct: 117  CHHGATCRNLADRYECHCPLGYAGVTCETEVDECASAPCLHGASCLDGVGSFRCVCAPGY 176

Query: 931  KGKECSLRHDECEVPDCNGHGHC---VNG-KCSCV-RGYKGKFCGE--IDCPHPTCSGHG 983
             G  C L  DEC+   C   G C   VNG +C C   GY+G  C    ++C    C  + 
Sbjct: 177  GGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNA 236

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC 1039
             C+EG     C+C  G+ G  C  +D+D  +C      HG   +     S  A + G   
Sbjct: 237  SCLEGLGSFRCLCWPGYSGELC-EVDED--ECASSPCQHGGRCLQR---SDPALYGG--- 287

Query: 1040 SKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL--CDAR-CAEHGQCK---NG-TCLC 1092
              +             G  C C  G+ G  C V +  C +R C   G C+   NG  C C
Sbjct: 288  -VQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHC 346

Query: 1093 VSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
              G+ G  C   ++ C      HG    D    + C+C + W G DC+
Sbjct: 347  PDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCS 394



 Score = 73.3 bits (172), Expect = 1e-11
 Identities = 66/237 (27%), Positives = 90/237 (37%), Gaps = 29/237 (12%)

Query: 893  CQCQ-PGFGGDDCSKSVCPVL---CSQRGEYING----ECQCNPGWKGKECSLRHDECEV 944
            C C   G+ G  C + V       C      + G     C C PG+ G+ C +  DEC  
Sbjct: 208  CDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECAS 267

Query: 945  PDCNGHGHCV-NGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGT 1003
              C   G C+     +   G +  F G     H      GF     C C  G++GADCG 
Sbjct: 268  SPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAA----GF----LCHCPPGFEGADCG- 318

Query: 1004 MDKDALQCLPDCSGHGTFDVDTQ-TCSCHAKWSGEDCSKEV--C-SLECGPHGRC----V 1055
            ++ D     P  +G    D+     C C   ++G  C ++V  C S  C   G C     
Sbjct: 319  VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVA 378

Query: 1056 GESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAG 1112
            G  C C   W G  CSV+L    C  H      TC+ +   +G H  +  CP    G
Sbjct: 379  GYICRCPETWGGRDCSVQL--TGCQGHTCPLAATCIPIFE-SGVHSYVCHCPPGTHG 432



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 6/65 (9%)

Query: 1079 CAEHGQCKN----GTCLCVSGWNGRHCT--LEGCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
            C   G C++      C C  GW G  C   ++ C  +    G+C    DGR+EC+C  G+
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPPGF 1124

Query: 1133 DGPDC 1137
             GP C
Sbjct: 1125 GGPRC 1129



 Score = 41.5 bits (93), Expect = 0.045
 Identities = 34/100 (34%), Positives = 39/100 (39%), Gaps = 9/100 (9%)

Query: 1048 CGPHGRCVG-ESCSCAAG-WSGEFCSVRLCD--ARCAEHGQCKNG-TCLCVSGWNGRHCT 1102
            C P   C   ES     G      C+ + C   A C   G   NG  C CV G+ G  C 
Sbjct: 47   CAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPNGFRCYCVPGFQGPRCE 106

Query: 1103 L---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            L   E   R C     CR   D R+EC C  G+ G  C T
Sbjct: 107  LDIDECASRPCHHGATCRNLAD-RYECHCPLGYAGVTCET 145



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 15/94 (15%)

Query: 893 CQCQPGFGGDDCSKSVCPVL---CSQRG---EYINGE-CQCNPGWKGKECSLRHDECEVP 945
           C C  G+ G  C + V   L   C   G   + + G  C+C   W G++CS++   C+  
Sbjct: 344 CHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGH 403

Query: 946 DCNGHGHCV--------NGKCSCVRGYKGKFCGE 971
            C     C+        +  C C  G  G FCG+
Sbjct: 404 TCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQ 437



 Score = 39.1 bits (87), Expect = 0.24
 Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 6/75 (8%)

Query: 900  GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNG 956
            G   C+ S C    + R  +    C C PGW+G  C    D C    C   G C    +G
Sbjct: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPC-ARGRCHTHPDG 1114

Query: 957  K--CSCVRGYKGKFC 969
            +  C C  G+ G  C
Sbjct: 1115 RFECRCPPGFGGPRC 1129


>AK075065-1|BAC11381.1|  269|Homo sapiens protein ( Homo sapiens cDNA
            FLJ90584 fis, clone PLACE1000740, highly similar to
            Neurogenic locus notch homolog protein 2 precursor. ).
          Length = 269

 Score = 91.1 bits (216), Expect = 6e-17
 Identities = 63/214 (29%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKK 994
            C   G CV      G C C  G+ G++C   D C    C   G C+      + TC C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFSGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECG 1049
            G+ G DC             C   GT  +   DT  C+C   ++G++C   + C S  C 
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 1050 PHGRCVGE----SCSCAAGWSGEFCS--VRLCD--ARCAEHGQCKN--GT--CLCVSGWN 1097
                C       SC C  G++G+ C   V  CD    C   G C N  G+  C C+ G+ 
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFT 214

Query: 1098 GRHCT---LEGCPRSCAGHGQCRVDNDGRWECKC 1128
            G++C    +   P  C   G CR   D  +EC C
Sbjct: 215  GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNC 248



 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 49/188 (26%), Positives = 78/188 (41%), Gaps = 27/188 (14%)

Query: 979  CSGHGFCIE-----GTCVCKKGWKGADCGTMDK-DALQCLPDCSGHGTFDVDTQTCSCHA 1032
            C   G C+      G C C +G+ G  C   D  +  +C    +      +   TC C +
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFSGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 1033 KWSGEDC---SKEVC--SLECGPHGRCVGES-----CSCAAGWSGEFCS-VRLCDAR-CA 1080
             ++GEDC   +   C  S  C   G C   S     C+C  G++G+ C     C +  CA
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 1081 EHGQC----KNGTCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
                C       +C C++G+ G+ C  +      P  C   G C ++  G ++C+C  G+
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTC-LNLPGSYQCQCLQGF 213

Query: 1133 DGPDCTTL 1140
             G  C +L
Sbjct: 214  TGQYCDSL 221



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 50/171 (29%), Positives = 67/171 (39%), Gaps = 32/171 (18%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 71   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 129

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 130  ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 188

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGT 1020
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT
Sbjct: 189  P-GHCQHGGTCLNLPGSYQCQCLQGFTGQYC---DSLYVPCAPSPCVNGGT 235



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 53/207 (25%), Positives = 81/207 (39%), Gaps = 34/207 (16%)

Query: 882  CSGKGECLM-----GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNP 928
            C  +G C+      G+C+C  GF G      D C K+ C     C  +       C+C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFSGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 929  GWKGKEC--SLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCS 980
            G+ G++C  S  H       C   G C        +C+C  G+ GK C   D C    C+
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154

Query: 981  GHGFCI----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHA 1032
                C     + +C C  G+ G  C T   D  +C +P    HG   ++   +  C C  
Sbjct: 155  NGSTCTTVANQFSCKCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCLQ 211

Query: 1033 KWSGEDCSKEVCSLECGPHGRCVGESC 1059
             ++G+ C  +   + C P     G +C
Sbjct: 212  GFTGQYC--DSLYVPCAPSPCVNGGTC 236



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 8/88 (9%)

Query: 874 MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
           ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 149 LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 208

Query: 926 CNPGWKGKECSLRHDECEVPDCNGHGHC 953
           C  G+ G+ C   +  C    C   G C
Sbjct: 209 CLQGFTGQYCDSLYVPCAPSPCVNGGTC 236



 Score = 41.9 bits (94), Expect = 0.034
 Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 16/118 (13%)

Query: 1079 CAEHGQC---KNGT--CLCVSGWNGRHCT-LEGCPRS-CAGHGQCRVDND-GRWECKCFD 1130
            C   G C    NGT  C C  G++G +C   + C ++ C   G C      G+  C+C  
Sbjct: 35   CVNEGMCVTYHNGTGYCKCPEGFSGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94

Query: 1131 GWDGPDCTTLKEQICDDSRDNDKDG---LVDCEDPEC-CQ----SPACKSSQLCVSSP 1180
            G+ G DC       C  SR     G   ++  +  EC CQ       C+ +  C+S P
Sbjct: 95   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 152


>AB052951-1|BAC53753.1|  866|Homo sapiens SRECRP-1 protein.
          Length = 866

 Score = 90.6 bits (215), Expect = 7e-17
 Identities = 83/273 (30%), Positives = 108/273 (39%), Gaps = 61/273 (22%)

Query: 882  CSGKGECLM-GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD 940
            CS    C+  G C+C+ G+ G +C  + CP                   W G +C     
Sbjct: 86   CSENEVCVRPGECRCRHGYFGANCD-TKCP----------------RQFW-GPDCK---- 123

Query: 941  ECEVPDCNGHGHC--VNGKCSCVRGYKGKFCGE-IDCPHPTCSGHGFCIEGTCVCKKGWK 997
              E+  C+ HG C  V G+C+C     G  C     C H TC        G C C+ GW 
Sbjct: 124  --ELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPR----SGACRCESGWW 177

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            GA C      A  C   CS     D  T  C CHA W G  C+ + C+    P  +  G 
Sbjct: 178  GAQC------ASACY--CSATSRCDPQTGACLCHAGWWGRSCNNQ-CACNSSPCEQQSGR 228

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPRSCAG--- 1112
             C C     G  C  R C  +C   G+C   +GTC C  G+ G++C  E CP    G   
Sbjct: 229  -CQCRERTFGARCD-RYC--QCF-RGRCHPVDGTCACEPGYRGKYCR-EPCPAGFYGLGC 282

Query: 1113 ---HGQCRVDN-----DGRWECKCFDGWDGPDC 1137
                GQC+        +GR    C  GW+G  C
Sbjct: 283  RRRCGQCKGQQPCTVAEGRC-LTCEPGWNGTKC 314



 Score = 86.2 bits (204), Expect = 2e-15
 Identities = 74/272 (27%), Positives = 104/272 (38%), Gaps = 48/272 (17%)

Query: 878  CPNGCSGK-GEC--LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            C + C  + G C    G C+C+ G+ G  C+ S C    + R +   G C C+ GW G+ 
Sbjct: 152  CEHACQCQHGTCHPRSGACRCESGWWGAQCA-SACYCSATSRCDPQTGACLCHAGWWGRS 210

Query: 935  CSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGE-IDCPHPTCSGHGFCIEGTCVCK 993
            C+     C    C       +G+C C     G  C     C    C      ++GTC C+
Sbjct: 211  CN-NQCACNSSPCEQQ----SGRCQCRERTFGARCDRYCQCFRGRCHP----VDGTCACE 261

Query: 994  KGWKGADC------GTMDKDALQCLPDCSGHGTFDVDTQTC-SCHAKWSGEDCSK----- 1041
             G++G  C      G       +    C G     V    C +C   W+G  C +     
Sbjct: 262  PGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATG 321

Query: 1042 ---EVCSLECGP----H--GRCVGESCSCAAGWSGEFCSVRL--------CDARCAE--H 1082
               E CS  C P    H      G+   C AGW G+ C  +         C   CA+   
Sbjct: 322  FYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGS 381

Query: 1083 GQC--KNGTCLCVSGWNGRHCTLEGCPRSCAG 1112
            G C  ++G CLC  G +G HC +  CP    G
Sbjct: 382  GHCDFQSGRCLCSPGVHGPHCNVT-CPPGLHG 412



 Score = 84.6 bits (200), Expect = 5e-15
 Identities = 66/213 (30%), Positives = 89/213 (41%), Gaps = 25/213 (11%)

Query: 959  SCVRGYK--GKFCGEIDCP-HPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL---QC 1011
            +C  G++  G  CG   C  + TCS +  C+  G C C+ G+ GA+C T          C
Sbjct: 63   TCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDC 122

Query: 1012 --LPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES--CSCAAGWSG 1067
              L  C  HG  +  T  C+CHA+  G  C +  C  +C  HG C   S  C C +GW G
Sbjct: 123  KELCSCHPHGQCEDVTGQCTCHARRWGARC-EHAC--QC-QHGTCHPRSGACRCESGWWG 178

Query: 1068 EFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECK 1127
              C+   C          + G CLC +GW GR C        CA +        GR  C+
Sbjct: 179  AQCA-SACYCSATSRCDPQTGACLCHAGWWGRSCN-----NQCACNSSPCEQQSGR--CQ 230

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCE 1160
            C +   G  C    +  C   R +  DG   CE
Sbjct: 231  CRERTFGARCDRYCQ--CFRGRCHPVDGTCACE 261



 Score = 84.6 bits (200), Expect = 5e-15
 Identities = 77/253 (30%), Positives = 98/253 (38%), Gaps = 47/253 (18%)

Query: 882  CSGKGEC--LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH 939
            CS    C    G C C  G+ G  C+   C    S   E  +G CQC     G  C  R+
Sbjct: 187  CSATSRCDPQTGACLCHAGWWGRSCNNQ-C-ACNSSPCEQQSGRCQCRERTFGARCD-RY 243

Query: 940  DECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPH-----------PTCSGHGFC--I 986
             +C      G  H V+G C+C  GY+GK+C E  CP              C G   C   
Sbjct: 244  CQC----FRGRCHPVDGTCACEPGYRGKYCRE-PCPAGFYGLGCRRRCGQCKGQQPCTVA 298

Query: 987  EGTCV-CKKGWKGADC------GTMDKDALQCLPDC-SGHGTFDVDTQTCSCHAKWSGED 1038
            EG C+ C+ GW G  C      G   +      P C  GH    V  +   C+A W G+ 
Sbjct: 299  EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358

Query: 1039 CSK--------EVCSLECGP--HGRCVGES--CSCAAGWSGEFCSVR----LCDARCAEH 1082
            C          E C+  C     G C  +S  C C+ G  G  C+V     L  A CA+ 
Sbjct: 359  CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQA 418

Query: 1083 GQCKNGTCLCVSG 1095
              C   TC  V+G
Sbjct: 419  CSCHEDTCDPVTG 431



 Score = 64.9 bits (151), Expect = 4e-09
 Identities = 47/151 (31%), Positives = 61/151 (40%), Gaps = 26/151 (17%)

Query: 1018 HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDA 1077
            HG F  +  T  C  ++ G DC KE+CS  C PHG+C   +  C        C  R   A
Sbjct: 102  HGYFGANCDT-KCPRQFWGPDC-KELCS--CHPHGQCEDVTGQCT-------CHARRWGA 150

Query: 1078 RCAEHGQCKNGTC-------LCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFD 1130
            RC    QC++GTC        C SGW G  C    C   C+   +C         C C  
Sbjct: 151  RCEHACQCQHGTCHPRSGACRCESGWWGAQCA-SAC--YCSATSRCDPQTGA---CLCHA 204

Query: 1131 GWDGPDCTTLKEQICDDSRDNDKDGLVDCED 1161
            GW G  C    +  C+ S    + G   C +
Sbjct: 205  GWWGRSCN--NQCACNSSPCEQQSGRCQCRE 233


>BC110320-1|AAI10321.1|  383|Homo sapiens EGF-like-domain, multiple 9
            protein.
          Length = 383

 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 76/245 (31%), Positives = 103/245 (42%), Gaps = 39/245 (15%)

Query: 888  CLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDEC-EVPD 946
            C++G    QP    DDCS S C +         +G C+C+PGW+G  C    + C  +P 
Sbjct: 15   CILG-APGQP-VRADDCS-SHCDLAHGCCAP--DGSCRCDPGWEGLHC----ERCVRMPG 65

Query: 947  CNGHGHCVNG-KCSCVRGYKGKFCGE---IDCPHPTCSGHGFCI-----EGTCVCKKGWK 997
            C  HG C    +C C  G+ GKFC +   I      C   G C+     E  CVC  G+ 
Sbjct: 66   CQ-HGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFH 124

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQ-----TCSCHAKWSGEDCSKEV--CSLE-CG 1049
            G DC        Q    C   G    D       TC C   + G  C   V  C +  C 
Sbjct: 125  GRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCA 184

Query: 1050 PHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHGQCKNGT----CLCVSGWNG 1098
                C+      SC C  G++G FC++ L  C +R C    +C++      CLC SG+ G
Sbjct: 185  NGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGG 244

Query: 1099 RHCTL 1103
            + C L
Sbjct: 245  KTCEL 249



 Score = 87.4 bits (207), Expect = 7e-16
 Identities = 66/212 (31%), Positives = 97/212 (45%), Gaps = 34/212 (16%)

Query: 953  CVNGKCS-CVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDALQ 1010
            C++  C  C+ G  G+     DC       HG C  +G+C C  GW+G  C    +    
Sbjct: 7    CLHLVCLLCILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVR---- 62

Query: 1011 CLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE--VCSLE--CGPHGRCV----GE-SCSC 1061
             +P C  HGT     Q C CH+ W+G+ C K+  +C+ +  C   G+C+    GE  C C
Sbjct: 63   -MPGCQ-HGTCHQPWQ-CICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC 119

Query: 1062 AAGWSGEFCSVRL--CD---ARCAEHGQCK-------NGTCLCVSGWNGRHC--TLEGC- 1106
              G+ G  C  +   C+   + C   GQC+       N TC C+ G+ G  C   ++ C 
Sbjct: 120  LPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCL 179

Query: 1107 PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             R CA    C +D   R+ C C +G+ G  CT
Sbjct: 180  MRPCANGATC-LDGINRFSCLCPEGFAGRFCT 210



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 43/135 (31%), Positives = 59/135 (43%), Gaps = 10/135 (7%)

Query: 1036 GEDCSKEVCSLECG-PHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQCKNG-TCLC 1092
            G+    + CS  C   HG C  + SC C  GW G  C   +    C +HG C     C+C
Sbjct: 21   GQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGC-QHGTCHQPWQCIC 79

Query: 1093 VSGWNGRHCTLEG--CPRS--CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
             SGW G+ C  +   C     C   GQC  D  G + C C  G+ G DC   K   C+ +
Sbjct: 80   HSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCER-KAGPCEQA 138

Query: 1149 RDNDKDGLVDCEDPE 1163
                ++G   C+D +
Sbjct: 139  GSPCRNG-GQCQDDQ 152



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 58/225 (25%), Positives = 86/225 (38%), Gaps = 28/225 (12%)

Query: 877  NCPNGCSGKGECLM--GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            +C + C     C    G C+C PG+ G  C + V    C     +   +C C+ GW GK 
Sbjct: 28   DCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWAGKF 87

Query: 935  CSLRHDECEVPD-CNGHGHCV---NGK--CSCVRGYKGKFC----GEIDCPHPTC----- 979
            C      C     C   G C+    G+  C C+ G+ G+ C    G  +     C     
Sbjct: 88   CDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQ 147

Query: 980  --SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSG 1036
                 GF +  TC C  G+ GA C     D L   P  +G    D ++  +C C   ++G
Sbjct: 148  CQDDQGFALNFTCRCLVGFVGARCEVNVDDCLM-RPCANGATCLDGINRFSCLCPEGFAG 206

Query: 1037 -------EDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL 1074
                   +DC+   C        R     C C +G+ G+ C + L
Sbjct: 207  RFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVL 251


>BC084572-1|AAH84572.1|  343|Homo sapiens NOTCH2NL protein protein.
          Length = 343

 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 63/214 (29%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKK 994
            C   G CV      G C C  G+ G++C   D C    C   G C+      + TC C  
Sbjct: 103  CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 162

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECG 1049
            G+ G DC             C   GT  +   DT  C+C   ++G++C   + C S  C 
Sbjct: 163  GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 222

Query: 1050 PHGRCVGE----SCSCAAGWSGEFCS--VRLCD--ARCAEHGQCKN--GT--CLCVSGWN 1097
                C       SC C  G++G+ C   V  CD    C   G C N  G+  C C+ G+ 
Sbjct: 223  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFT 282

Query: 1098 GRHCT---LEGCPRSCAGHGQCRVDNDGRWECKC 1128
            G++C    +   P  C   G CR   D  +EC C
Sbjct: 283  GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNC 316



 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 49/188 (26%), Positives = 78/188 (41%), Gaps = 27/188 (14%)

Query: 979  CSGHGFCIE-----GTCVCKKGWKGADCGTMDK-DALQCLPDCSGHGTFDVDTQTCSCHA 1032
            C   G C+      G C C +G+ G  C   D  +  +C    +      +   TC C +
Sbjct: 103  CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 162

Query: 1033 KWSGEDC---SKEVC--SLECGPHGRCVGES-----CSCAAGWSGEFCS-VRLCDAR-CA 1080
             ++GEDC   +   C  S  C   G C   S     C+C  G++G+ C     C +  CA
Sbjct: 163  GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 222

Query: 1081 EHGQC----KNGTCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
                C       +C C++G+ G+ C  +      P  C   G C ++  G ++C+C  G+
Sbjct: 223  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTC-LNLPGSYQCQCLQGF 281

Query: 1133 DGPDCTTL 1140
             G  C +L
Sbjct: 282  TGQYCDSL 289



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 50/171 (29%), Positives = 67/171 (39%), Gaps = 32/171 (18%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 139  NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 197

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 198  ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 256

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGT 1020
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT
Sbjct: 257  P-GHCQHGGTCLNLPGSYQCQCLQGFTGQYC---DSLYVPCAPSPCVNGGT 303



 Score = 53.6 bits (123), Expect = 1e-05
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 13/106 (12%)

Query: 893 CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
           C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 199 CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 258

Query: 947 -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFC 985
            C   G C+N     +C C++G+ G++C    + C    C   G C
Sbjct: 259 HCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTC 304



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 53/207 (25%), Positives = 81/207 (39%), Gaps = 34/207 (16%)

Query: 882  CSGKGECLM-----GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNP 928
            C  +G C+      G+C+C  GF G      D C K+ C     C  +       C+C  
Sbjct: 103  CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 162

Query: 929  GWKGKEC--SLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCS 980
            G+ G++C  S  H       C   G C        +C+C  G+ GK C   D C    C+
Sbjct: 163  GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 222

Query: 981  GHGFCI----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHA 1032
                C     + +C C  G+ G  C T   D  +C +P    HG   ++   +  C C  
Sbjct: 223  NGSTCTTVANQFSCKCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCLQ 279

Query: 1033 KWSGEDCSKEVCSLECGPHGRCVGESC 1059
             ++G+ C  +   + C P     G +C
Sbjct: 280  GFTGQYC--DSLYVPCAPSPCVNGGTC 304



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 8/88 (9%)

Query: 874 MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
           ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 217 LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 276

Query: 926 CNPGWKGKECSLRHDECEVPDCNGHGHC 953
           C  G+ G+ C   +  C    C   G C
Sbjct: 277 CLQGFTGQYCDSLYVPCAPSPCVNGGTC 304



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 34/118 (28%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 1079 CAEHGQC---KNGT--CLCVSGWNGRHCT-LEGCPRS-CAGHGQCRVDND-GRWECKCFD 1130
            C   G C    NGT  C C  G+ G +C   + C ++ C   G C      G+  C+C  
Sbjct: 103  CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 162

Query: 1131 GWDGPDCTTLKEQICDDSRDNDKDG---LVDCEDPEC-CQ----SPACKSSQLCVSSP 1180
            G+ G DC       C  SR     G   ++  +  EC CQ       C+ +  C+S P
Sbjct: 163  GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 220


>AY358126-1|AAQ88493.1|  383|Homo sapiens PSGC2903 protein.
          Length = 383

 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 76/245 (31%), Positives = 103/245 (42%), Gaps = 39/245 (15%)

Query: 888  CLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDEC-EVPD 946
            C++G    QP    DDCS S C +         +G C+C+PGW+G  C    + C  +P 
Sbjct: 15   CILG-APGQP-VRADDCS-SHCDLAHGCCAP--DGSCRCDPGWEGLHC----ERCVRMPG 65

Query: 947  CNGHGHCVNG-KCSCVRGYKGKFCGE---IDCPHPTCSGHGFCI-----EGTCVCKKGWK 997
            C  HG C    +C C  G+ GKFC +   I      C   G C+     E  CVC  G+ 
Sbjct: 66   CQ-HGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFH 124

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQ-----TCSCHAKWSGEDCSKEV--CSLE-CG 1049
            G DC        Q    C   G    D       TC C   + G  C   V  C +  C 
Sbjct: 125  GRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCA 184

Query: 1050 PHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHGQCKNGT----CLCVSGWNG 1098
                C+      SC C  G++G FC++ L  C +R C    +C++      CLC SG+ G
Sbjct: 185  NGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGG 244

Query: 1099 RHCTL 1103
            + C L
Sbjct: 245  KTCEL 249



 Score = 87.4 bits (207), Expect = 7e-16
 Identities = 66/212 (31%), Positives = 97/212 (45%), Gaps = 34/212 (16%)

Query: 953  CVNGKCS-CVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDALQ 1010
            C++  C  C+ G  G+     DC       HG C  +G+C C  GW+G  C    +    
Sbjct: 7    CLHLVCLLCILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVR---- 62

Query: 1011 CLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE--VCSLE--CGPHGRCV----GE-SCSC 1061
             +P C  HGT     Q C CH+ W+G+ C K+  +C+ +  C   G+C+    GE  C C
Sbjct: 63   -MPGCQ-HGTCHQPWQ-CICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC 119

Query: 1062 AAGWSGEFCSVRL--CD---ARCAEHGQCK-------NGTCLCVSGWNGRHC--TLEGC- 1106
              G+ G  C  +   C+   + C   GQC+       N TC C+ G+ G  C   ++ C 
Sbjct: 120  LPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCL 179

Query: 1107 PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             R CA    C +D   R+ C C +G+ G  CT
Sbjct: 180  MRPCANGATC-LDGINRFSCLCPEGFAGRFCT 210



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 43/135 (31%), Positives = 59/135 (43%), Gaps = 10/135 (7%)

Query: 1036 GEDCSKEVCSLECG-PHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQCKNG-TCLC 1092
            G+    + CS  C   HG C  + SC C  GW G  C   +    C +HG C     C+C
Sbjct: 21   GQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGC-QHGTCHQPWQCIC 79

Query: 1093 VSGWNGRHCTLEG--CPRS--CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
             SGW G+ C  +   C     C   GQC  D  G + C C  G+ G DC   K   C+ +
Sbjct: 80   HSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCER-KAGPCEQA 138

Query: 1149 RDNDKDGLVDCEDPE 1163
                ++G   C+D +
Sbjct: 139  GSPCRNG-GQCQDDQ 152



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 58/225 (25%), Positives = 86/225 (38%), Gaps = 28/225 (12%)

Query: 877  NCPNGCSGKGECLM--GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            +C + C     C    G C+C PG+ G  C + V    C     +   +C C+ GW GK 
Sbjct: 28   DCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWAGKF 87

Query: 935  CSLRHDECEVPD-CNGHGHCV---NGK--CSCVRGYKGKFC----GEIDCPHPTC----- 979
            C      C     C   G C+    G+  C C+ G+ G+ C    G  +     C     
Sbjct: 88   CDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQ 147

Query: 980  --SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSG 1036
                 GF +  TC C  G+ GA C     D L   P  +G    D ++  +C C   ++G
Sbjct: 148  CQDDQGFALNFTCRCLVGFVGARCEVNVDDCLM-RPCANGATCLDGINRFSCLCPEGFAG 206

Query: 1037 -------EDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL 1074
                   +DC+   C        R     C C +G+ G+ C + L
Sbjct: 207  RFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVL 251


>AL359813-9|CAI23224.1|  383|Homo sapiens EGF-like-domain, multiple 9
            protein.
          Length = 383

 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 76/245 (31%), Positives = 103/245 (42%), Gaps = 39/245 (15%)

Query: 888  CLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDEC-EVPD 946
            C++G    QP    DDCS S C +         +G C+C+PGW+G  C    + C  +P 
Sbjct: 15   CILG-APGQP-VRADDCS-SHCDLAHGCCAP--DGSCRCDPGWEGLHC----ERCVRMPG 65

Query: 947  CNGHGHCVNG-KCSCVRGYKGKFCGE---IDCPHPTCSGHGFCI-----EGTCVCKKGWK 997
            C  HG C    +C C  G+ GKFC +   I      C   G C+     E  CVC  G+ 
Sbjct: 66   CQ-HGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFH 124

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQ-----TCSCHAKWSGEDCSKEV--CSLE-CG 1049
            G DC        Q    C   G    D       TC C   + G  C   V  C +  C 
Sbjct: 125  GRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCA 184

Query: 1050 PHGRCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHGQCKNGT----CLCVSGWNG 1098
                C+      SC C  G++G FC++ L  C +R C    +C++      CLC SG+ G
Sbjct: 185  NGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGG 244

Query: 1099 RHCTL 1103
            + C L
Sbjct: 245  KTCEL 249



 Score = 87.4 bits (207), Expect = 7e-16
 Identities = 66/212 (31%), Positives = 97/212 (45%), Gaps = 34/212 (16%)

Query: 953  CVNGKCS-CVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDALQ 1010
            C++  C  C+ G  G+     DC       HG C  +G+C C  GW+G  C    +    
Sbjct: 7    CLHLVCLLCILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVR---- 62

Query: 1011 CLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE--VCSLE--CGPHGRCV----GE-SCSC 1061
             +P C  HGT     Q C CH+ W+G+ C K+  +C+ +  C   G+C+    GE  C C
Sbjct: 63   -MPGCQ-HGTCHQPWQ-CICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC 119

Query: 1062 AAGWSGEFCSVRL--CD---ARCAEHGQCK-------NGTCLCVSGWNGRHC--TLEGC- 1106
              G+ G  C  +   C+   + C   GQC+       N TC C+ G+ G  C   ++ C 
Sbjct: 120  LPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCL 179

Query: 1107 PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             R CA    C +D   R+ C C +G+ G  CT
Sbjct: 180  MRPCANGATC-LDGINRFSCLCPEGFAGRFCT 210



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 43/135 (31%), Positives = 59/135 (43%), Gaps = 10/135 (7%)

Query: 1036 GEDCSKEVCSLECG-PHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQCKNG-TCLC 1092
            G+    + CS  C   HG C  + SC C  GW G  C   +    C +HG C     C+C
Sbjct: 21   GQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGC-QHGTCHQPWQCIC 79

Query: 1093 VSGWNGRHCTLEG--CPRS--CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
             SGW G+ C  +   C     C   GQC  D  G + C C  G+ G DC   K   C+ +
Sbjct: 80   HSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCER-KAGPCEQA 138

Query: 1149 RDNDKDGLVDCEDPE 1163
                ++G   C+D +
Sbjct: 139  GSPCRNG-GQCQDDQ 152



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 58/225 (25%), Positives = 86/225 (38%), Gaps = 28/225 (12%)

Query: 877  NCPNGCSGKGECLM--GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            +C + C     C    G C+C PG+ G  C + V    C     +   +C C+ GW GK 
Sbjct: 28   DCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWAGKF 87

Query: 935  CSLRHDECEVPD-CNGHGHCV---NGK--CSCVRGYKGKFC----GEIDCPHPTC----- 979
            C      C     C   G C+    G+  C C+ G+ G+ C    G  +     C     
Sbjct: 88   CDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQ 147

Query: 980  --SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSG 1036
                 GF +  TC C  G+ GA C     D L   P  +G    D ++  +C C   ++G
Sbjct: 148  CQDDQGFALNFTCRCLVGFVGARCEVNVDDCLM-RPCANGATCLDGINRFSCLCPEGFAG 206

Query: 1037 -------EDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL 1074
                   +DC+   C        R     C C +G+ G+ C + L
Sbjct: 207  RFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVL 251


>AF522196-1|AAN45861.1|  870|Homo sapiens scavenger receptor type F
            protein.
          Length = 870

 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 83/273 (30%), Positives = 108/273 (39%), Gaps = 61/273 (22%)

Query: 882  CSGKGECLM-GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD 940
            CS    C+  G C+C+ G+ G +C  + CP                   W G +C     
Sbjct: 86   CSENEVCVRPGECRCRHGYFGANCD-TKCP----------------RQFW-GPDCK---- 123

Query: 941  ECEVPDCNGHGHC--VNGKCSCVRGYKGKFCGE-IDCPHPTCSGHGFCIEGTCVCKKGWK 997
              E+  C+ HG C  V G+C+C     G  C     C H TC        G C C+ GW 
Sbjct: 124  --ELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPR----SGACRCEPGWW 177

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            GA C      A  C   CS     D  T  C CHA W G  C+ + C+    P  +  G 
Sbjct: 178  GAQC------ASACY--CSATSRCDPQTGACLCHAGWWGRSCNNQ-CACNSSPCEQQSGR 228

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPRSCAG--- 1112
             C C     G  C  R C  +C   G+C   +GTC C  G+ G++C  E CP    G   
Sbjct: 229  -CQCRERTFGARCD-RYC--QCF-RGRCHPVDGTCACEPGYRGKYCR-EPCPAGFYGLGC 282

Query: 1113 ---HGQCRVDN-----DGRWECKCFDGWDGPDC 1137
                GQC+        +GR    C  GW+G  C
Sbjct: 283  RRRCGQCKGQQPCTVAEGRC-LTCEPGWNGTKC 314



 Score = 84.6 bits (200), Expect = 5e-15
 Identities = 77/253 (30%), Positives = 98/253 (38%), Gaps = 47/253 (18%)

Query: 882  CSGKGEC--LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH 939
            CS    C    G C C  G+ G  C+   C    S   E  +G CQC     G  C  R+
Sbjct: 187  CSATSRCDPQTGACLCHAGWWGRSCNNQ-C-ACNSSPCEQQSGRCQCRERTFGARCD-RY 243

Query: 940  DECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPH-----------PTCSGHGFC--I 986
             +C      G  H V+G C+C  GY+GK+C E  CP              C G   C   
Sbjct: 244  CQC----FRGRCHPVDGTCACEPGYRGKYCRE-PCPAGFYGLGCRRRCGQCKGQQPCTVA 298

Query: 987  EGTCV-CKKGWKGADC------GTMDKDALQCLPDC-SGHGTFDVDTQTCSCHAKWSGED 1038
            EG C+ C+ GW G  C      G   +      P C  GH    V  +   C+A W G+ 
Sbjct: 299  EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358

Query: 1039 CSK--------EVCSLECGP--HGRCVGES--CSCAAGWSGEFCSVR----LCDARCAEH 1082
            C          E C+  C     G C  +S  C C+ G  G  C+V     L  A CA+ 
Sbjct: 359  CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQA 418

Query: 1083 GQCKNGTCLCVSG 1095
              C   TC  V+G
Sbjct: 419  CSCHEDTCDPVTG 431



 Score = 83.8 bits (198), Expect = 8e-15
 Identities = 66/213 (30%), Positives = 88/213 (41%), Gaps = 25/213 (11%)

Query: 959  SCVRGYK--GKFCGEIDCP-HPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL---QC 1011
            +C  G++  G  CG   C  + TCS +  C+  G C C+ G+ GA+C T          C
Sbjct: 63   TCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDC 122

Query: 1012 --LPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES--CSCAAGWSG 1067
              L  C  HG  +  T  C+CHA+  G  C +  C  +C  HG C   S  C C  GW G
Sbjct: 123  KELCSCHPHGQCEDVTGQCTCHARRWGARC-EHAC--QC-QHGTCHPRSGACRCEPGWWG 178

Query: 1068 EFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECK 1127
              C+   C          + G CLC +GW GR C        CA +        GR  C+
Sbjct: 179  AQCA-SACYCSATSRCDPQTGACLCHAGWWGRSCN-----NQCACNSSPCEQQSGR--CQ 230

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCE 1160
            C +   G  C    +  C   R +  DG   CE
Sbjct: 231  CRERTFGARCDRYCQ--CFRGRCHPVDGTCACE 261



 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 76/290 (26%), Positives = 105/290 (36%), Gaps = 64/290 (22%)

Query: 882  CSGKGEC--LMGHCQCQPGFGGDDCSKSV-CPV-LCSQRGEYINGECQCNPGWKGKECS- 936
            C   G+C  + G C C     G  C  +  C    C  R    +G C+C PGW G +C+ 
Sbjct: 128  CHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPR----SGACRCEPGWWGAQCAS 183

Query: 937  ----LRHDEC--EVPDCNGH----GHCVNGKCSCVRGYKGKFCGEIDCPHPT----CSGH 982
                     C  +   C  H    G   N +C+C      +  G   C   T    C  +
Sbjct: 184  ACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRY 243

Query: 983  GFC-------IEGTCVCKKGWKGADC------GTMDKDALQCLPDCSGHGTFDVDTQTC- 1028
              C       ++GTC C+ G++G  C      G       +    C G     V    C 
Sbjct: 244  CQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCL 303

Query: 1029 SCHAKWSGEDCSK--------EVCSLECGP----H--GRCVGESCSCAAGWSGEFCSVRL 1074
            +C   W+G  C +        E CS  C P    H      G+   C AGW G+ C  + 
Sbjct: 304  TCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKC 363

Query: 1075 --------CDARCAE--HGQC--KNGTCLCVSGWNGRHCTLEGCPRSCAG 1112
                    C   CA+   G C  ++G CLC  G +G HC +  CP    G
Sbjct: 364  SNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVT-CPPGLHG 412


>AB024433-1|BAD93345.1|  866|Homo sapiens NSR1 protein.
          Length = 866

 Score = 90.2 bits (214), Expect = 1e-16
 Identities = 83/273 (30%), Positives = 108/273 (39%), Gaps = 61/273 (22%)

Query: 882  CSGKGECLM-GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD 940
            CS    C+  G C+C+ G+ G +C  + CP                   W G +C     
Sbjct: 86   CSENEVCVRPGECRCRHGYFGANCD-TKCP----------------RQFW-GPDCK---- 123

Query: 941  ECEVPDCNGHGHC--VNGKCSCVRGYKGKFCGE-IDCPHPTCSGHGFCIEGTCVCKKGWK 997
              E+  C+ HG C  V G+C+C     G  C     C H TC        G C C+ GW 
Sbjct: 124  --ELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPR----SGACRCEPGWW 177

Query: 998  GADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE 1057
            GA C      A  C   CS     D  T  C CHA W G  C+ + C+    P  +  G 
Sbjct: 178  GAQC------ASACY--CSATSRCDPQTGACLCHAGWWGRSCNNQ-CACNSSPCEQQSGR 228

Query: 1058 SCSCAAGWSGEFCSVRLCDARCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPRSCAG--- 1112
             C C     G  C  R C  +C   G+C   +GTC C  G+ G++C  E CP    G   
Sbjct: 229  -CQCRERTFGARCD-RYC--QCF-RGRCHPVDGTCACEPGYRGKYCR-EPCPAGFYGLGC 282

Query: 1113 ---HGQCRVDN-----DGRWECKCFDGWDGPDC 1137
                GQC+        +GR    C  GW+G  C
Sbjct: 283  RRRCGQCKGQQPCTVAEGRC-LTCEPGWNGTKC 314



 Score = 84.6 bits (200), Expect = 5e-15
 Identities = 77/253 (30%), Positives = 98/253 (38%), Gaps = 47/253 (18%)

Query: 882  CSGKGEC--LMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH 939
            CS    C    G C C  G+ G  C+   C    S   E  +G CQC     G  C  R+
Sbjct: 187  CSATSRCDPQTGACLCHAGWWGRSCNNQ-C-ACNSSPCEQQSGRCQCRERTFGARCD-RY 243

Query: 940  DECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPH-----------PTCSGHGFC--I 986
             +C      G  H V+G C+C  GY+GK+C E  CP              C G   C   
Sbjct: 244  CQC----FRGRCHPVDGTCACEPGYRGKYCRE-PCPAGFYGLGCRRRCGQCKGQQPCTVA 298

Query: 987  EGTCV-CKKGWKGADC------GTMDKDALQCLPDC-SGHGTFDVDTQTCSCHAKWSGED 1038
            EG C+ C+ GW G  C      G   +      P C  GH    V  +   C+A W G+ 
Sbjct: 299  EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358

Query: 1039 CSK--------EVCSLECGP--HGRCVGES--CSCAAGWSGEFCSVR----LCDARCAEH 1082
            C          E C+  C     G C  +S  C C+ G  G  C+V     L  A CA+ 
Sbjct: 359  CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQA 418

Query: 1083 GQCKNGTCLCVSG 1095
              C   TC  V+G
Sbjct: 419  CSCHEDTCDPVTG 431



 Score = 83.8 bits (198), Expect = 8e-15
 Identities = 66/213 (30%), Positives = 88/213 (41%), Gaps = 25/213 (11%)

Query: 959  SCVRGYK--GKFCGEIDCP-HPTCSGHGFCIE-GTCVCKKGWKGADCGTMDKDAL---QC 1011
            +C  G++  G  CG   C  + TCS +  C+  G C C+ G+ GA+C T          C
Sbjct: 63   TCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDC 122

Query: 1012 --LPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES--CSCAAGWSG 1067
              L  C  HG  +  T  C+CHA+  G  C +  C  +C  HG C   S  C C  GW G
Sbjct: 123  KELCSCHPHGQCEDVTGQCTCHARRWGARC-EHAC--QC-QHGTCHPRSGACRCEPGWWG 178

Query: 1068 EFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECK 1127
              C+   C          + G CLC +GW GR C        CA +        GR  C+
Sbjct: 179  AQCA-SACYCSATSRCDPQTGACLCHAGWWGRSCN-----NQCACNSSPCEQQSGR--CQ 230

Query: 1128 CFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCE 1160
            C +   G  C    +  C   R +  DG   CE
Sbjct: 231  CRERTFGARCDRYCQ--CFRGRCHPVDGTCACE 261



 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 76/290 (26%), Positives = 105/290 (36%), Gaps = 64/290 (22%)

Query: 882  CSGKGEC--LMGHCQCQPGFGGDDCSKSV-CPV-LCSQRGEYINGECQCNPGWKGKECS- 936
            C   G+C  + G C C     G  C  +  C    C  R    +G C+C PGW G +C+ 
Sbjct: 128  CHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPR----SGACRCEPGWWGAQCAS 183

Query: 937  ----LRHDEC--EVPDCNGH----GHCVNGKCSCVRGYKGKFCGEIDCPHPT----CSGH 982
                     C  +   C  H    G   N +C+C      +  G   C   T    C  +
Sbjct: 184  ACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRY 243

Query: 983  GFC-------IEGTCVCKKGWKGADC------GTMDKDALQCLPDCSGHGTFDVDTQTC- 1028
              C       ++GTC C+ G++G  C      G       +    C G     V    C 
Sbjct: 244  CQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCL 303

Query: 1029 SCHAKWSGEDCSK--------EVCSLECGP----H--GRCVGESCSCAAGWSGEFCSVRL 1074
            +C   W+G  C +        E CS  C P    H      G+   C AGW G+ C  + 
Sbjct: 304  TCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKC 363

Query: 1075 --------CDARCAE--HGQC--KNGTCLCVSGWNGRHCTLEGCPRSCAG 1112
                    C   CA+   G C  ++G CLC  G +G HC +  CP    G
Sbjct: 364  SNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVT-CPPGLHG 412


>AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequence
            DNA binding protein-1 protein.
          Length = 1008

 Score = 89.8 bits (213), Expect = 1e-16
 Identities = 79/295 (26%), Positives = 105/295 (35%), Gaps = 35/295 (11%)

Query: 876  HNCPNG-CSGKGECLMG----HCQCQPGFGGDDCS----KSVCPVLCSQRG---EYING- 922
            H C +G C   G C       HC C   F G  C      S     C   G    YI   
Sbjct: 197  HLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKY 256

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGK----CSCVRGYKGKFC-GEIDCPHP 977
            +C C PG+ G+ C +    C    C   G C +      C C  GY G+ C  E+DC  P
Sbjct: 257  KCDCPPGFSGRYCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPP 316

Query: 978  TCSGHG-FCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSG 1036
                H      GT +        D G     A   +  C  HG +    Q          
Sbjct: 317  EEVKHATLRFNGTRLGAAALYACDRG-YSLSAPSRIRVCQPHGVWSEPPQCLEI------ 369

Query: 1037 EDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDAR---CAEHGQCKN----GT 1089
            ++C  + C        R  G  C C+ G+ G  C +   + R   C   G C+N      
Sbjct: 370  DECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYV 429

Query: 1090 CLCVSGWNGRHCTLE--GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
            C C +G+ G HC  E   C  S   HG       G + C C +G+ G  C T+ +
Sbjct: 430  CRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPEGFFGYHCETVSD 484



 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 54/177 (30%), Positives = 74/177 (41%), Gaps = 23/177 (12%)

Query: 879  PNGC-SGKGECL-MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            P+G  S   +CL +  C+ QP   G  C   V   LC            C+ G++G  C 
Sbjct: 356  PHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCL-----------CSTGYEGAHCE 404

Query: 937  LRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGKFC-GEID-CPHPTCSGHGFCIEG-- 988
            L  DEC    C   G C N  G   C C  G+ G  C  E+D C    C   G C  G  
Sbjct: 405  LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 464

Query: 989  --TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEV 1043
               CVC +G+ G  C T+            G+      + +C+C   ++GEDC+KE+
Sbjct: 465  AYLCVCPEGFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 521



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 55/196 (28%), Positives = 77/196 (39%), Gaps = 24/196 (12%)

Query: 973  DCPHPTCSGHGFCIE----GTCVCKKGWKGADCGTMDK---DALQCLPDCSGHGTFDVDT 1025
            DC    C   G C++     TC+C + +KG  C T D    DA    P  +G    D D 
Sbjct: 5    DCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQ 64

Query: 1026 -QTCSCHAKWSGEDCSKEVCS-LECGPHGRCVGES---CSCAAGWSGEFCSVRLCDARCA 1080
               C C   + G DC + V    EC   GRC+G +   C C  G+ G  C   +    C 
Sbjct: 65   GYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCN 124

Query: 1081 EHGQCKNG----------TCLCVSGWNGRHCTLEGCPRS-CAGHGQCRVDNDGRWECKCF 1129
             + QC +G           C+C +  N  H     C    C   G C   +D  + C+C 
Sbjct: 125  MNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCNSDPCFNGGSCDAHDDS-YTCECP 183

Query: 1130 DGWDGPDCTTLKEQIC 1145
             G+ G  C   +  +C
Sbjct: 184  RGFHGKHCEKARPHLC 199



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 68/277 (24%), Positives = 99/277 (35%), Gaps = 39/277 (14%)

Query: 940  DECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEIDCPHP------TCSGHGFCIEG- 988
            D+C    C   G CV    N  C C   +KG  C   D P P       C   G C++  
Sbjct: 4    DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDAD 63

Query: 989  ---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCS 1045
                C C +G+ G DC     D  +C    +G      +T  C C   + G  C  E+ +
Sbjct: 64   QGYVCECPEGFMGLDCRERVPDDCECR---NGGRCLGANTTLCQCPLGFFGLLCEFEITA 120

Query: 1046 LECGPHGRCV--------GES--CSCAAGWSGEFCSVRLCDA-RCAEHGQC----KNGTC 1090
            + C  + +C         G S  C C    +        C++  C   G C     + TC
Sbjct: 121  MPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCNSDPCFNGGSCDAHDDSYTC 180

Query: 1091 LCVSGWNGRHCTLEGCPRSCAGHGQCR-----VDNDGRWECKCFDGWDGPDCTTLKEQIC 1145
             C  G++G+HC  +  P  C+  G CR      +  G + C C   + G  C   K   C
Sbjct: 181  ECPRGFHGKHCE-KARPHLCSS-GPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSC 238

Query: 1146 DDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSPKP 1182
                 ++            C  P   S + C  +P P
Sbjct: 239  ASGPCHNGGTCFHYIGKYKCDCPPGFSGRYCEIAPSP 275



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 80/285 (28%), Positives = 105/285 (36%), Gaps = 59/285 (20%)

Query: 882  CSGKGECL---MGH-CQCQPGFGGDDCSKSV-CPVLCSQRGEYINGE---CQCNPGWKGK 933
            C   G C+    G+ C+C  GF G DC + V     C   G  +      CQC  G+ G 
Sbjct: 53   CHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGL 112

Query: 934  ECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCK 993
             C     E     CN +  C +G      GY  +  G   C   T       +   C   
Sbjct: 113  LCEF---EITAMPCNMNTQCPDG------GYCMEHGGSYLCVCHTDHNASHSLPSPCNSD 163

Query: 994  KGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK---EVCSL-ECG 1049
              + G  C   D                  D+ TC C   + G+ C K    +CS   C 
Sbjct: 164  PCFNGGSCDAHD------------------DSYTCECPRGFHGKHCEKARPHLCSSGPCR 205

Query: 1050 PHGRCV---GE-SCSCAAGWSGEFCSVRLCDARCAEHGQCKN-GTCL---------CVSG 1095
              G C    GE  CSC   ++G  C +   D+ CA  G C N GTC          C  G
Sbjct: 206  NGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDS-CAS-GPCHNGGTCFHYIGKYKCDCPPG 263

Query: 1096 WNGRHCTL--EGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            ++GR+C +    C RS C   G C  D D  + C C  G+ G  C
Sbjct: 264  FSGRYCEIAPSPCFRSPCVNGGTCE-DRDTDFFCHCQAGYMGRRC 307



 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 52/170 (30%), Positives = 66/170 (38%), Gaps = 21/170 (12%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNGK-CSCVRGYKGKFCG--EIDCPHP 977
            CQ +  W      L  DEC    C   G C   V G  C C  GY+G  C     +C   
Sbjct: 354  CQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAH 413

Query: 978  TCSGHGFC--IEGT--CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVD--TQTCSCH 1031
             C   G C  + G   C C  G+ G  C T + DA    P C   G  +       C C 
Sbjct: 414  PCRNGGSCRNLPGAYVCRCPAGFVGVHCET-EVDACDSSP-CQHGGRCESGGGAYLCVCP 471

Query: 1032 AKWSGEDCS--KEVC-SLECGPHGRCVGE----SCSCAAGWSGEFCSVRL 1074
              + G  C    + C S  CG  G C+      SC+C  G++GE C+  L
Sbjct: 472  EGFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 521



 Score = 58.4 bits (135), Expect = 4e-07
 Identities = 61/236 (25%), Positives = 87/236 (36%), Gaps = 22/236 (9%)

Query: 924  CQCNPGWKGKECS-LRHDECEVPDCNGHGHC--VNGK--CSCVRGYKGKFC--GEID-CP 975
            C+C  G+ GK C   R   C    C   G C    G+  CSC   + G+ C  G+ D C 
Sbjct: 180  CECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCA 239

Query: 976  HPTCSGHGFCI----EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-CSC 1030
               C   G C     +  C C  G+ G  C        +  P  +G    D DT   C C
Sbjct: 240  SGPCHNGGTCFHYIGKYKCDCPPGFSGRYCEIAPSPCFRS-PCVNGGTCEDRDTDFFCHC 298

Query: 1031 HAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTC 1090
             A + G  C  EV   +CGP    V  +     G      ++  CD   +     +   C
Sbjct: 299  QAGYMGRRCQAEV---DCGPPEE-VKHATLRFNGTRLGAAALYACDRGYSLSAPSRIRVC 354

Query: 1091 LCVSGWNGRHCTLE--GC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQ 1143
                 W+     LE   C  + C   G C+ D    + C C  G++G  C   +++
Sbjct: 355  QPHGVWSEPPQCLEIDECRSQPCLHGGSCQ-DRVAGYLCLCSTGYEGAHCELERDE 409



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 64/257 (24%), Positives = 86/257 (33%), Gaps = 34/257 (13%)

Query: 882  CSGKGECLMGH---CQCQPGFGGDDCSKSVCPVLCSQRGEYINGE-CQCNPGWKGKECSL 937
            C   G CL  +   CQC  GF G  C   +  + C+   +  +G  C  + G     C  
Sbjct: 89   CRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHT 148

Query: 938  RHDE-------CEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEID---CPHPTCSGHG 983
             H+        C    C   G C     +  C C RG+ GK C +     C    C   G
Sbjct: 149  DHNASHSLPSPCNSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGG 208

Query: 984  FCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSGED 1038
             C E      C C   + G  C     D+    P  +G   F  +    C C   +SG  
Sbjct: 209  TCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRY 268

Query: 1039 C--SKEVC-SLECGPHGRCVGES----CSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCL 1091
            C  +   C    C   G C        C C AG+ G  C     +  C    + K+ T L
Sbjct: 269  CEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQ---AEVDCGPPEEVKHAT-L 324

Query: 1092 CVSGWNGRHCTLEGCPR 1108
              +G       L  C R
Sbjct: 325  RFNGTRLGAAALYACDR 341



 Score = 34.3 bits (75), Expect = 6.8
 Identities = 13/33 (39%), Positives = 20/33 (60%), Gaps = 4/33 (12%)

Query: 882 CSGKGECLMGH----CQCQPGFGGDDCSKSVCP 910
           C G+G CL  +    C C+ G+ G+DC+K + P
Sbjct: 491 CGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 523


>BX537434-1|CAD97676.1|  236|Homo sapiens hypothetical protein
            protein.
          Length = 236

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 60/204 (29%), Positives = 83/204 (40%), Gaps = 27/204 (13%)

Query: 952  HCVNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKKGWKGADCGTM 1004
            H   G C C  G+ G++C   D C    C   G C+      + TC C  G+ G DC   
Sbjct: 6    HNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYS 65

Query: 1005 DKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECGPHGRCVGE-- 1057
                      C   GT  +   DT  C+C   ++G++C   + C S  C     C     
Sbjct: 66   TSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN 125

Query: 1058 --SCSCAAGWSGEFCS--VRLCD--ARCAEHGQCKN--GT--CLCVSGWNGRHCT---LE 1104
              SC C  G++G+ C   V  CD    C   G C N  G+  C C+ G+ G++C    + 
Sbjct: 126  QFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVP 185

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKC 1128
              P  C   G CR   D  +EC C
Sbjct: 186  CAPSPCVNGGTCRQTGDFTFECNC 209



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 22/174 (12%)

Query: 988  GTCVCKKGWKGADCGTMDK-DALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC---SKEV 1043
            G C C +G+ G  C   D  +  +C    +      +   TC C + ++GEDC   +   
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1044 C--SLECGPHGRCVGES-----CSCAAGWSGEFCS-VRLCDAR-CAEHGQC----KNGTC 1090
            C  S  C   G C   S     C+C  G++G+ C     C +  CA    C       +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 1091 LCVSGWNGRHCTLE----GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
             C++G+ G+ C  +      P  C   G C ++  G ++C+C  G+ G  C +L
Sbjct: 130  KCLTGFTGQKCETDVNECDIPGHCQHGGTC-LNLPGSYQCQCLQGFTGQYCDSL 182



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 50/171 (29%), Positives = 67/171 (39%), Gaps = 32/171 (18%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 32   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 90

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 91   ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 149

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGT 1020
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT
Sbjct: 150  P-GHCQHGGTCLNLPGSYQCQCLQGFTGQYC---DSLYVPCAPSPCVNGGT 196



 Score = 53.6 bits (123), Expect = 1e-05
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 13/106 (12%)

Query: 893 CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
           C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 92  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 151

Query: 947 -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFC 985
            C   G C+N     +C C++G+ G++C    + C    C   G C
Sbjct: 152 HCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 50/193 (25%), Positives = 76/193 (39%), Gaps = 29/193 (15%)

Query: 891  GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKEC--SLRHD 940
            G+C+C  GF G      D C K+ C     C  +       C+C  G+ G++C  S  H 
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 941  ECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI----EGTC 990
                  C   G C        +C+C  G+ GK C   D C    C+    C     + +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 991  VCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSL 1046
             C  G+ G  C T   D  +C +P    HG   ++   +  C C   ++G+ C  +   +
Sbjct: 130  KCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYC--DSLYV 184

Query: 1047 ECGPHGRCVGESC 1059
             C P     G +C
Sbjct: 185  PCAPSPCVNGGTC 197



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 8/88 (9%)

Query: 874 MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
           ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 110 LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 169

Query: 926 CNPGWKGKECSLRHDECEVPDCNGHGHC 953
           C  G+ G+ C   +  C    C   G C
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 11/104 (10%)

Query: 1088 GTCLCVSGWNGRHCT-LEGCPRS-CAGHGQCRVDND-GRWECKCFDGWDGPDCTTLKEQI 1144
            G C C  G+ G +C   + C ++ C   G C      G+  C+C  G+ G DC       
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1145 CDDSRDNDKDG---LVDCEDPEC-CQ----SPACKSSQLCVSSP 1180
            C  SR     G   ++  +  EC CQ       C+ +  C+S P
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 113


>BC090943-1|AAH90943.1|  249|Homo sapiens NOTCH2NL protein protein.
          Length = 249

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 63/214 (29%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKK 994
            C   G CV      G C C  G+ G++C   D C    C   G C+      + TC C  
Sbjct: 9    CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 68

Query: 995  GWKGADCGTMDKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECG 1049
            G+ G DC             C   GT  +   DT  C+C   ++G++C   + C S  C 
Sbjct: 69   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 128

Query: 1050 PHGRCVGE----SCSCAAGWSGEFCS--VRLCD--ARCAEHGQCKN--GT--CLCVSGWN 1097
                C       SC C  G++G+ C   V  CD    C   G C N  G+  C C+ G+ 
Sbjct: 129  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQCLQGFT 188

Query: 1098 GRHCT---LEGCPRSCAGHGQCRVDNDGRWECKC 1128
            G++C    +   P  C   G CR   D  +EC C
Sbjct: 189  GQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNC 222



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 49/188 (26%), Positives = 78/188 (41%), Gaps = 27/188 (14%)

Query: 979  CSGHGFCIE-----GTCVCKKGWKGADCGTMDK-DALQCLPDCSGHGTFDVDTQTCSCHA 1032
            C   G C+      G C C +G+ G  C   D  +  +C    +      +   TC C +
Sbjct: 9    CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 68

Query: 1033 KWSGEDC---SKEVC--SLECGPHGRCVGES-----CSCAAGWSGEFCS-VRLCDAR-CA 1080
             ++GEDC   +   C  S  C   G C   S     C+C  G++G+ C     C +  CA
Sbjct: 69   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 128

Query: 1081 EHGQC----KNGTCLCVSGWNGRHCTLE----GCPRSCAGHGQCRVDNDGRWECKCFDGW 1132
                C       +C C++G+ G+ C  +      P  C   G C ++  G ++C+C  G+
Sbjct: 129  NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGIC-LNLPGSYQCQCLQGF 187

Query: 1133 DGPDCTTL 1140
             G  C +L
Sbjct: 188  TGQYCDSL 195



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 50/171 (29%), Positives = 67/171 (39%), Gaps = 32/171 (18%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 45   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 103

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 104  ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 162

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGT 1020
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT
Sbjct: 163  P-GHCQHGGICLNLPGSYQCQCLQGFTGQYC---DSLYVPCAPSPCVNGGT 209



 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 53/207 (25%), Positives = 81/207 (39%), Gaps = 34/207 (16%)

Query: 882  CSGKGECLM-----GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNP 928
            C  +G C+      G+C+C  GF G      D C K+ C     C  +       C+C  
Sbjct: 9    CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 68

Query: 929  GWKGKEC--SLRHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCS 980
            G+ G++C  S  H       C   G C        +C+C  G+ GK C   D C    C+
Sbjct: 69   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 128

Query: 981  GHGFCI----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHA 1032
                C     + +C C  G+ G  C T   D  +C +P    HG   ++   +  C C  
Sbjct: 129  NGSTCTTVANQFSCKCLTGFTGQKCET---DVNECDIPGHCQHGGICLNLPGSYQCQCLQ 185

Query: 1033 KWSGEDCSKEVCSLECGPHGRCVGESC 1059
             ++G+ C  +   + C P     G +C
Sbjct: 186  GFTGQYC--DSLYVPCAPSPCVNGGTC 210



 Score = 41.5 bits (93), Expect = 0.045
 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 8/88 (9%)

Query: 874 MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
           ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 123 LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQ 182

Query: 926 CNPGWKGKECSLRHDECEVPDCNGHGHC 953
           C  G+ G+ C   +  C    C   G C
Sbjct: 183 CLQGFTGQYCDSLYVPCAPSPCVNGGTC 210



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 34/118 (28%), Positives = 48/118 (40%), Gaps = 16/118 (13%)

Query: 1079 CAEHGQC---KNGT--CLCVSGWNGRHCT-LEGCPRS-CAGHGQCRVDND-GRWECKCFD 1130
            C   G C    NGT  C C  G+ G +C   + C ++ C   G C      G+  C+C  
Sbjct: 9    CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 68

Query: 1131 GWDGPDCTTLKEQICDDSRDNDKDG---LVDCEDPEC-CQ----SPACKSSQLCVSSP 1180
            G+ G DC       C  SR     G   ++  +  EC CQ       C+ +  C+S P
Sbjct: 69   GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 126


>BC010154-1|AAH10154.3|  236|Homo sapiens Notch homolog 2 (Drosophila)
            N-terminal like protein.
          Length = 236

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 60/204 (29%), Positives = 83/204 (40%), Gaps = 27/204 (13%)

Query: 952  HCVNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKKGWKGADCGTM 1004
            H   G C C  G+ G++C   D C    C   G C+      + TC C  G+ G DC   
Sbjct: 6    HNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYS 65

Query: 1005 DKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECGPHGRCVGE-- 1057
                      C   GT  +   DT  C+C   ++G++C   + C S  C     C     
Sbjct: 66   TSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN 125

Query: 1058 --SCSCAAGWSGEFCS--VRLCD--ARCAEHGQCKN--GT--CLCVSGWNGRHCT---LE 1104
              SC C  G++G+ C   V  CD    C   G C N  G+  C C+ G+ G++C    + 
Sbjct: 126  QFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVP 185

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKC 1128
              P  C   G CR   D  +EC C
Sbjct: 186  CAPSPCVNGGTCRQTGDFTFECNC 209



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 22/174 (12%)

Query: 988  GTCVCKKGWKGADCGTMDK-DALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC---SKEV 1043
            G C C +G+ G  C   D  +  +C    +      +   TC C + ++GEDC   +   
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1044 C--SLECGPHGRCVGES-----CSCAAGWSGEFCS-VRLCDAR-CAEHGQC----KNGTC 1090
            C  S  C   G C   S     C+C  G++G+ C     C +  CA    C       +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 1091 LCVSGWNGRHCTLE----GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
             C++G+ G+ C  +      P  C   G C ++  G ++C+C  G+ G  C +L
Sbjct: 130  KCLTGFTGQKCETDVNECDIPGHCQHGGTC-LNLPGSYQCQCLQGFTGQYCDSL 182



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 50/171 (29%), Positives = 67/171 (39%), Gaps = 32/171 (18%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 32   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 90

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 91   ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 149

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGT 1020
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT
Sbjct: 150  P-GHCQHGGTCLNLPGSYQCQCLQGFTGQYC---DSLYVPCAPSPCVNGGT 196



 Score = 53.6 bits (123), Expect = 1e-05
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 13/106 (12%)

Query: 893 CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
           C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 92  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 151

Query: 947 -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFC 985
            C   G C+N     +C C++G+ G++C    + C    C   G C
Sbjct: 152 HCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 50/193 (25%), Positives = 76/193 (39%), Gaps = 29/193 (15%)

Query: 891  GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKEC--SLRHD 940
            G+C+C  GF G      D C K+ C     C  +       C+C  G+ G++C  S  H 
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 941  ECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI----EGTC 990
                  C   G C        +C+C  G+ GK C   D C    C+    C     + +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 991  VCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSL 1046
             C  G+ G  C T   D  +C +P    HG   ++   +  C C   ++G+ C  +   +
Sbjct: 130  KCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYC--DSLYV 184

Query: 1047 ECGPHGRCVGESC 1059
             C P     G +C
Sbjct: 185  PCAPSPCVNGGTC 197



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 8/88 (9%)

Query: 874 MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
           ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 110 LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 169

Query: 926 CNPGWKGKECSLRHDECEVPDCNGHGHC 953
           C  G+ G+ C   +  C    C   G C
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 11/104 (10%)

Query: 1088 GTCLCVSGWNGRHCT-LEGCPRS-CAGHGQCRVDND-GRWECKCFDGWDGPDCTTLKEQI 1144
            G C C  G+ G +C   + C ++ C   G C      G+  C+C  G+ G DC       
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1145 CDDSRDNDKDG---LVDCEDPEC-CQ----SPACKSSQLCVSSP 1180
            C  SR     G   ++  +  EC CQ       C+ +  C+S P
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 113


>AL592307-2|CAH73994.1|  230|Homo sapiens Notch homolog 2 (Drosophila)
            N-terminal like protein.
          Length = 230

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 60/204 (29%), Positives = 83/204 (40%), Gaps = 27/204 (13%)

Query: 952  HCVNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKKGWKGADCGTM 1004
            H   G C C  G+ G++C   D C    C   G C+      + TC C  G+ G DC   
Sbjct: 6    HNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYS 65

Query: 1005 DKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECGPHGRCVGE-- 1057
                      C   GT  +   DT  C+C   ++G++C   + C S  C     C     
Sbjct: 66   TSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN 125

Query: 1058 --SCSCAAGWSGEFCS--VRLCD--ARCAEHGQCKN--GT--CLCVSGWNGRHCT---LE 1104
              SC C  G++G+ C   V  CD    C   G C N  G+  C C+ G+ G++C    + 
Sbjct: 126  QFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVP 185

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKC 1128
              P  C   G CR   D  +EC C
Sbjct: 186  CAPSPCVNGGTCRQTGDFTFECNC 209



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 22/174 (12%)

Query: 988  GTCVCKKGWKGADCGTMDK-DALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC---SKEV 1043
            G C C +G+ G  C   D  +  +C    +      +   TC C + ++GEDC   +   
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1044 C--SLECGPHGRCVGES-----CSCAAGWSGEFCS-VRLCDAR-CAEHGQC----KNGTC 1090
            C  S  C   G C   S     C+C  G++G+ C     C +  CA    C       +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 1091 LCVSGWNGRHCTLE----GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
             C++G+ G+ C  +      P  C   G C ++  G ++C+C  G+ G  C +L
Sbjct: 130  KCLTGFTGQKCETDVNECDIPGHCQHGGTC-LNLPGSYQCQCLQGFTGQYCDSL 182



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 50/171 (29%), Positives = 67/171 (39%), Gaps = 32/171 (18%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 32   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 90

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 91   ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 149

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGT 1020
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT
Sbjct: 150  P-GHCQHGGTCLNLPGSYQCQCLQGFTGQYC---DSLYVPCAPSPCVNGGT 196



 Score = 53.6 bits (123), Expect = 1e-05
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 13/106 (12%)

Query: 893 CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
           C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 92  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 151

Query: 947 -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFC 985
            C   G C+N     +C C++G+ G++C    + C    C   G C
Sbjct: 152 HCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 50/193 (25%), Positives = 76/193 (39%), Gaps = 29/193 (15%)

Query: 891  GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKEC--SLRHD 940
            G+C+C  GF G      D C K+ C     C  +       C+C  G+ G++C  S  H 
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 941  ECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI----EGTC 990
                  C   G C        +C+C  G+ GK C   D C    C+    C     + +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 991  VCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSL 1046
             C  G+ G  C T   D  +C +P    HG   ++   +  C C   ++G+ C  +   +
Sbjct: 130  KCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYC--DSLYV 184

Query: 1047 ECGPHGRCVGESC 1059
             C P     G +C
Sbjct: 185  PCAPSPCVNGGTC 197



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 8/88 (9%)

Query: 874 MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
           ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 110 LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 169

Query: 926 CNPGWKGKECSLRHDECEVPDCNGHGHC 953
           C  G+ G+ C   +  C    C   G C
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 11/104 (10%)

Query: 1088 GTCLCVSGWNGRHCT-LEGCPRS-CAGHGQCRVDND-GRWECKCFDGWDGPDCTTLKEQI 1144
            G C C  G+ G +C   + C ++ C   G C      G+  C+C  G+ G DC       
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1145 CDDSRDNDKDG---LVDCEDPEC-CQ----SPACKSSQLCVSSP 1180
            C  SR     G   ++  +  EC CQ       C+ +  C+S P
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 113


>AL592307-1|CAH73993.1|  236|Homo sapiens Notch homolog 2 (Drosophila)
            N-terminal like protein.
          Length = 236

 Score = 89.4 bits (212), Expect = 2e-16
 Identities = 60/204 (29%), Positives = 83/204 (40%), Gaps = 27/204 (13%)

Query: 952  HCVNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKKGWKGADCGTM 1004
            H   G C C  G+ G++C   D C    C   G C+      + TC C  G+ G DC   
Sbjct: 6    HNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYS 65

Query: 1005 DKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECGPHGRCVGE-- 1057
                      C   GT  +   DT  C+C   ++G++C   + C S  C     C     
Sbjct: 66   TSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN 125

Query: 1058 --SCSCAAGWSGEFCS--VRLCD--ARCAEHGQCKN--GT--CLCVSGWNGRHCT---LE 1104
              SC C  G++G+ C   V  CD    C   G C N  G+  C C+ G+ G++C    + 
Sbjct: 126  QFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVP 185

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKC 1128
              P  C   G CR   D  +EC C
Sbjct: 186  CAPSPCVNGGTCRQTGDFTFECNC 209



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 22/174 (12%)

Query: 988  GTCVCKKGWKGADCGTMDK-DALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC---SKEV 1043
            G C C +G+ G  C   D  +  +C    +      +   TC C + ++GEDC   +   
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1044 C--SLECGPHGRCVGES-----CSCAAGWSGEFCS-VRLCDAR-CAEHGQC----KNGTC 1090
            C  S  C   G C   S     C+C  G++G+ C     C +  CA    C       +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 1091 LCVSGWNGRHCTLE----GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
             C++G+ G+ C  +      P  C   G C ++  G ++C+C  G+ G  C +L
Sbjct: 130  KCLTGFTGQKCETDVNECDIPGHCQHGGTC-LNLPGSYQCQCLQGFTGQYCDSL 182



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 50/171 (29%), Positives = 67/171 (39%), Gaps = 32/171 (18%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 32   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 90

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 91   ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 149

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGT 1020
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT
Sbjct: 150  P-GHCQHGGTCLNLPGSYQCQCLQGFTGQYC---DSLYVPCAPSPCVNGGT 196



 Score = 53.6 bits (123), Expect = 1e-05
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 13/106 (12%)

Query: 893 CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
           C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 92  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 151

Query: 947 -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFC 985
            C   G C+N     +C C++G+ G++C    + C    C   G C
Sbjct: 152 HCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 51.6 bits (118), Expect = 4e-05
 Identities = 50/193 (25%), Positives = 76/193 (39%), Gaps = 29/193 (15%)

Query: 891  GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKEC--SLRHD 940
            G+C+C  GF G      D C K+ C     C  +       C+C  G+ G++C  S  H 
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 941  ECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI----EGTC 990
                  C   G C        +C+C  G+ GK C   D C    C+    C     + +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 991  VCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSL 1046
             C  G+ G  C T   D  +C +P    HG   ++   +  C C   ++G+ C  +   +
Sbjct: 130  KCLTGFTGQKCET---DVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYC--DSLYV 184

Query: 1047 ECGPHGRCVGESC 1059
             C P     G +C
Sbjct: 185  PCAPSPCVNGGTC 197



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 8/88 (9%)

Query: 874 MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
           ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 110 LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQ 169

Query: 926 CNPGWKGKECSLRHDECEVPDCNGHGHC 953
           C  G+ G+ C   +  C    C   G C
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 11/104 (10%)

Query: 1088 GTCLCVSGWNGRHCT-LEGCPRS-CAGHGQCRVDND-GRWECKCFDGWDGPDCTTLKEQI 1144
            G C C  G+ G +C   + C ++ C   G C      G+  C+C  G+ G DC       
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1145 CDDSRDNDKDG---LVDCEDPEC-CQ----SPACKSSQLCVSSP 1180
            C  SR     G   ++  +  EC CQ       C+ +  C+S P
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 113


>BC065219-1|AAH65219.2|  236|Homo sapiens Notch homolog 2 (Drosophila)
            N-terminal like protein.
          Length = 236

 Score = 88.6 bits (210), Expect = 3e-16
 Identities = 60/204 (29%), Positives = 83/204 (40%), Gaps = 27/204 (13%)

Query: 952  HCVNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKKGWKGADCGTM 1004
            H   G C C  G+ G++C   D C    C   G C+      + TC C  G+ G DC   
Sbjct: 6    HNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYS 65

Query: 1005 DKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECGPHGRCVGE-- 1057
                      C   GT  +   DT  C+C   ++G++C   + C S  C     C     
Sbjct: 66   TSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN 125

Query: 1058 --SCSCAAGWSGEFCS--VRLCD--ARCAEHGQCKN--GT--CLCVSGWNGRHCT---LE 1104
              SC C  G++G+ C   V  CD    C   G C N  G+  C C+ G+ G++C    + 
Sbjct: 126  QFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQCLQGFTGQYCDSLYVP 185

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKC 1128
              P  C   G CR   D  +EC C
Sbjct: 186  CAPSPCVNGGTCRQTGDFTFECNC 209



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 22/174 (12%)

Query: 988  GTCVCKKGWKGADCGTMDK-DALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC---SKEV 1043
            G C C +G+ G  C   D  +  +C    +      +   TC C + ++GEDC   +   
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1044 C--SLECGPHGRCVGES-----CSCAAGWSGEFCS-VRLCDAR-CAEHGQC----KNGTC 1090
            C  S  C   G C   S     C+C  G++G+ C     C +  CA    C       +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 1091 LCVSGWNGRHCTLE----GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
             C++G+ G+ C  +      P  C   G C ++  G ++C+C  G+ G  C +L
Sbjct: 130  KCLTGFTGQKCETDVNECDIPGHCQHGGIC-LNLPGSYQCQCLQGFTGQYCDSL 182



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 50/171 (29%), Positives = 67/171 (39%), Gaps = 32/171 (18%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 32   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 90

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 91   ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 149

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGT 1020
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT
Sbjct: 150  P-GHCQHGGICLNLPGSYQCQCLQGFTGQYC---DSLYVPCAPSPCVNGGT 196



 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 13/106 (12%)

Query: 893 CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
           C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 92  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 151

Query: 947 -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFC 985
            C   G C+N     +C C++G+ G++C    + C    C   G C
Sbjct: 152 HCQHGGICLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 50/193 (25%), Positives = 76/193 (39%), Gaps = 29/193 (15%)

Query: 891  GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKEC--SLRHD 940
            G+C+C  GF G      D C K+ C     C  +       C+C  G+ G++C  S  H 
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 941  ECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI----EGTC 990
                  C   G C        +C+C  G+ GK C   D C    C+    C     + +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 991  VCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSL 1046
             C  G+ G  C T   D  +C +P    HG   ++   +  C C   ++G+ C  +   +
Sbjct: 130  KCLTGFTGQKCET---DVNECDIPGHCQHGGICLNLPGSYQCQCLQGFTGQYC--DSLYV 184

Query: 1047 ECGPHGRCVGESC 1059
             C P     G +C
Sbjct: 185  PCAPSPCVNGGTC 197



 Score = 41.5 bits (93), Expect = 0.045
 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 8/88 (9%)

Query: 874 MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
           ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 110 LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQ 169

Query: 926 CNPGWKGKECSLRHDECEVPDCNGHGHC 953
           C  G+ G+ C   +  C    C   G C
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 11/104 (10%)

Query: 1088 GTCLCVSGWNGRHCT-LEGCPRS-CAGHGQCRVDND-GRWECKCFDGWDGPDCTTLKEQI 1144
            G C C  G+ G +C   + C ++ C   G C      G+  C+C  G+ G DC       
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1145 CDDSRDNDKDG---LVDCEDPEC-CQ----SPACKSSQLCVSSP 1180
            C  SR     G   ++  +  EC CQ       C+ +  C+S P
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 113


>BC019835-1|AAH19835.1|  236|Homo sapiens Notch homolog 2 N-terminal
            like protein protein.
          Length = 236

 Score = 88.6 bits (210), Expect = 3e-16
 Identities = 60/204 (29%), Positives = 83/204 (40%), Gaps = 27/204 (13%)

Query: 952  HCVNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI------EGTCVCKKGWKGADCGTM 1004
            H   G C C  G+ G++C   D C    C   G C+      + TC C  G+ G DC   
Sbjct: 6    HNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYS 65

Query: 1005 DKDALQCLPDCSGHGTFDV---DTQTCSCHAKWSGEDCS-KEVC-SLECGPHGRCVGE-- 1057
                      C   GT  +   DT  C+C   ++G++C   + C S  C     C     
Sbjct: 66   TSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN 125

Query: 1058 --SCSCAAGWSGEFCS--VRLCD--ARCAEHGQCKN--GT--CLCVSGWNGRHCT---LE 1104
              SC C  G++G+ C   V  CD    C   G C N  G+  C C+ G+ G++C    + 
Sbjct: 126  QFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQCLQGFTGQYCDSLYVP 185

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKC 1128
              P  C   G CR   D  +EC C
Sbjct: 186  CAPSPCVNGGTCRQTGDFTFECNC 209



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 22/174 (12%)

Query: 988  GTCVCKKGWKGADCGTMDK-DALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDC---SKEV 1043
            G C C +G+ G  C   D  +  +C    +      +   TC C + ++GEDC   +   
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1044 C--SLECGPHGRCVGES-----CSCAAGWSGEFCS-VRLCDAR-CAEHGQC----KNGTC 1090
            C  S  C   G C   S     C+C  G++G+ C     C +  CA    C       +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 1091 LCVSGWNGRHCTLE----GCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
             C++G+ G+ C  +      P  C   G C ++  G ++C+C  G+ G  C +L
Sbjct: 130  KCLTGFTGQKCETDVNECDIPGHCQHGGIC-LNLPGSYQCQCLQGFTGQYCDSL 182



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 50/171 (29%), Positives = 67/171 (39%), Gaps = 32/171 (18%)

Query: 876  HNCPNGCSGKGECLMGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYING----------- 922
            + C NG +   + ++G   C+C  GF G+DC  S     C      +NG           
Sbjct: 32   NRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP-CFVSRPCLNGGTCHMLSRDTY 90

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFC----GEIDC 974
            EC C  G+ GKEC    D C    C     C        C C+ G+ G+ C     E D 
Sbjct: 91   ECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDI 149

Query: 975  PHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQCLPD-CSGHGT 1020
            P   C   G C+   G+  C C +G+ G  C   D   + C P  C   GT
Sbjct: 150  P-GHCQHGGICLNLPGSYQCQCLQGFTGQYC---DSLYVPCAPSPCVNGGT 196



 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 13/106 (12%)

Query: 893 CQCQPGFGGDDCS-KSVC---PVLCSQRGEYINGE--CQCNPGWKGKECSLRHDECEVPD 946
           C CQ GF G +C     C   P         +  +  C+C  G+ G++C    +EC++P 
Sbjct: 92  CTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPG 151

Query: 947 -CNGHGHCVN----GKCSCVRGYKGKFCGE--IDCPHPTCSGHGFC 985
            C   G C+N     +C C++G+ G++C    + C    C   G C
Sbjct: 152 HCQHGGICLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 50/193 (25%), Positives = 76/193 (39%), Gaps = 29/193 (15%)

Query: 891  GHCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGECQCNPGWKGKEC--SLRHD 940
            G+C+C  GF G      D C K+ C     C  +       C+C  G+ G++C  S  H 
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 941  ECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEID-CPHPTCSGHGFCI----EGTC 990
                  C   G C        +C+C  G+ GK C   D C    C+    C     + +C
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSC 129

Query: 991  VCKKGWKGADCGTMDKDALQC-LPDCSGHGTFDVD---TQTCSCHAKWSGEDCSKEVCSL 1046
             C  G+ G  C T   D  +C +P    HG   ++   +  C C   ++G+ C  +   +
Sbjct: 130  KCLTGFTGQKCET---DVNECDIPGHCQHGGICLNLPGSYQCQCLQGFTGQYC--DSLYV 184

Query: 1047 ECGPHGRCVGESC 1059
             C P     G +C
Sbjct: 185  PCAPSPCVNGGTC 197



 Score = 41.5 bits (93), Expect = 0.045
 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 8/88 (9%)

Query: 874 MTHNCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV--C--PVLCSQRGEYIN----GECQ 925
           ++H C NG +         C+C  GF G  C   V  C  P  C   G  +N     +CQ
Sbjct: 110 LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQ 169

Query: 926 CNPGWKGKECSLRHDECEVPDCNGHGHC 953
           C  G+ G+ C   +  C    C   G C
Sbjct: 170 CLQGFTGQYCDSLYVPCAPSPCVNGGTC 197



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 11/104 (10%)

Query: 1088 GTCLCVSGWNGRHCT-LEGCPRS-CAGHGQCRVDND-GRWECKCFDGWDGPDCTTLKEQI 1144
            G C C  G+ G +C   + C ++ C   G C      G+  C+C  G+ G DC       
Sbjct: 10   GYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP 69

Query: 1145 CDDSRDNDKDG---LVDCEDPEC-CQ----SPACKSSQLCVSSP 1180
            C  SR     G   ++  +  EC CQ       C+ +  C+S P
Sbjct: 70   CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 113


>AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein.
          Length = 1736

 Score = 88.2 bits (209), Expect = 4e-16
 Identities = 73/250 (29%), Positives = 104/250 (41%), Gaps = 45/250 (18%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN-----GKCSCVRGYKGK 967
            C +R   +    +C  G+ G++C       + P CN  G C++     G+C C  G+ G 
Sbjct: 1122 CRERCSLVIQIPRCCKGYFGRDCQACPGGPDAP-CNNRGVCLDQYSATGECKCNTGFNGT 1180

Query: 968  FC-----GEI--DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDC 1015
             C     G    DC    CS HG C +G      C+C+ GW G  C T       C P C
Sbjct: 1181 ACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGTSCDTQAVLPAVCTPPC 1240

Query: 1016 SGHGTFDVDTQTCSCHAKWSGE--DCS-KEVCSLE---CGPHGRCVGE----SCSCAAGW 1065
            S H T   +  TC C+  + G+   C+  + C  +   C    RC  +    SCSC  G+
Sbjct: 1241 SAHATCK-ENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGY 1299

Query: 1066 SGE--FCS-VRLC----DARCAEHGQCK-----NGTCLCVSGW--NGRHCTLEGCP--RS 1109
             G+   C+ +  C    +  C EH  CK        C C S +  +G +C  E  P  R 
Sbjct: 1300 KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRC 1359

Query: 1110 CAGHGQCRVD 1119
               +GQC  D
Sbjct: 1360 LQDNGQCHAD 1369



 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 61/222 (27%), Positives = 89/222 (40%), Gaps = 39/222 (17%)

Query: 960  CVRGYKGKFCGEIDC-PHPTCSGHGFCIE-----GTCVCKKGWKGADC-----GTMDKDA 1008
            C +GY G+ C      P   C+  G C++     G C C  G+ G  C     G    D 
Sbjct: 1135 CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDC 1194

Query: 1009 LQCLPDCSGHGTFD---VDTQTCSCHAKWSGEDCSKE-----VCSLECGPHGRCV-GESC 1059
            L C   CS HG  D     +  C C   W+G  C  +     VC+  C  H  C    +C
Sbjct: 1195 LPC--GCSDHGQCDDGITGSGQCLCETGWTGTSCDTQAVLPAVCTPPCSAHATCKENNTC 1252

Query: 1060 SCAAGWSGE--FCSV-RLC---DARCAEHGQC-KNGT---CLCVSGW--NGRHCT----- 1102
             C   + G+   C+V   C   +  CA+  +C + GT   C C  G+  +G  CT     
Sbjct: 1253 ECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPC 1312

Query: 1103 LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQI 1144
             +G    C  H  C++   G+ +C+C   + G       EQ+
Sbjct: 1313 ADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQL 1354



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 64/225 (28%), Positives = 87/225 (38%), Gaps = 42/225 (18%)

Query: 878  CPNG----CSGKGECL-----MGHCQCQPGFGGDDC--------SKSVCPVLCSQRGEYI 920
            CP G    C+ +G CL      G C+C  GF G  C             P  CS  G+  
Sbjct: 1147 CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCD 1206

Query: 921  -----NGECQCNPGWKGKECSLRHDECEV--PDCNGHGHC-VNGKCSCVRGYKGK--FCG 970
                 +G+C C  GW G  C  +     V  P C+ H  C  N  C C   Y+G    C 
Sbjct: 1207 DGITGSGQCLCETGWTGTSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCT 1266

Query: 971  EID-CPHPT--CSGHGFCIE-GT---CVCKKGWK--GADCGTMDKDALQCLPDCSGHGTF 1021
             +D C      C+    C + GT   C C+KG+K  G  C  +D  A      C  H T 
Sbjct: 1267 VVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATC 1326

Query: 1022 DV---DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
             +       C C + + G+  +   C  E  P  RC+ ++  C A
Sbjct: 1327 KMTGPGKHKCECKSHYVGDGLN---CEPEQLPIDRCLQDNGQCHA 1368



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 57/211 (27%), Positives = 80/211 (37%), Gaps = 47/211 (22%)

Query: 877  NCPNGCSGKGECL-----MGHCQCQPGFGGDDCSKSV-------CPVLCS------QRGE 918
            N  N C G G CL      G C+C  GF G  C           C   CS       +G 
Sbjct: 536  NAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGP 595

Query: 919  YINGECQCNPGWKGKEC--SLRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGK--FC 969
              +G C C+ GW+G  C  +   D C    C+   +C+        C C  G++G    C
Sbjct: 596  LGDGSCDCDVGWRGVHCDNATTEDNCN-GTCHTSANCLTNSDGTASCKCAAGFQGNGTIC 654

Query: 970  GEI---DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF 1021
              I   +  +  CS    C   T     C CK G+ G   G +  +   CL +  G    
Sbjct: 655  TAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD--GIVCLEINPCLENHGGCDKN 712

Query: 1022 DVDTQT------CSCHAKWSGEDCSKEVCSL 1046
               TQT      C+C   ++G+    +VC+L
Sbjct: 713  AECTQTGPNQAACNCLPAYTGDG---KVCTL 740



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 17/93 (18%)

Query: 1059 CSCAAGWSGEFCSVRL-------CDARCA-EHGQCK-----NGTCLCVSGWNGRHC---- 1101
            C C  G+SG  C           CD  C+  HG+C      +G+C C  GW G HC    
Sbjct: 557  CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 616

Query: 1102 TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
            T + C  +C     C  ++DG   CKC  G+ G
Sbjct: 617  TEDNCNGTCHTSANCLTNSDGTASCKCAAGFQG 649



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 59/211 (27%), Positives = 80/211 (37%), Gaps = 54/211 (25%)

Query: 960  CVRGYKGKFCGEIDCP---HPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQC 1011
            C  G+ G  C    CP      C G+G C++G      C C +G+ G  C T        
Sbjct: 521  CCAGFFGPQCQP--CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET-------- 570

Query: 1012 LPDCSGHGTFDVDT-QTCSC-HAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEF 1069
               C+  G + +   Q CSC H +     C++       GP G     SC C  GW G  
Sbjct: 571  ---CT-EGKYGIHCDQACSCVHGR-----CNQ-------GPLG---DGSCDCDVGWRGVH 611

Query: 1070 CSVRL----CDARCAEHGQC---KNGT--CLCVSGW--NGRHCT-LEGCPRS---CAGHG 1114
            C        C+  C     C    +GT  C C +G+  NG  CT +  C  S   C+   
Sbjct: 612  CDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKA 671

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQIC 1145
             C+    GR  C C  G+ G     L+   C
Sbjct: 672  DCKRTTPGRRVCTCKAGYTGDGIVCLEINPC 702



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 47/153 (30%), Positives = 61/153 (39%), Gaps = 33/153 (21%)

Query: 1014 DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVC--------SLECGPHGRC--VGESCSCAA 1063
            D SG     V+T +C    +WS     K+ C        +LE G   RC  V +   C  
Sbjct: 1082 DASGECGSCVNTPSCP---RWSKPKGVKQKCLYNLPFKRNLE-GCRERCSLVIQIPRCCK 1137

Query: 1064 GWSGEFCSVRLC----DARCAEHGQCKN-----GTCLCVSGWNGRHCTL--------EGC 1106
            G+ G  C    C    DA C   G C +     G C C +G+NG  C +        +  
Sbjct: 1138 GYFGRDCQA--CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCL 1195

Query: 1107 PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            P  C+ HGQC     G  +C C  GW G  C T
Sbjct: 1196 PCGCSDHGQCDDGITGSGQCLCETGWTGTSCDT 1228



 Score = 48.4 bits (110), Expect = 4e-04
 Identities = 50/173 (28%), Positives = 68/173 (39%), Gaps = 33/173 (19%)

Query: 929  GWKGKECSLRHDECE--VPDCNGHGHCV--NGKCSCV--RGYKGK--FCGEID-CPHPT- 978
            G  G+ C  +   C   V  C+ H  C   NG  SC+   GY+G    C E+D C   T 
Sbjct: 2    GSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTP 61

Query: 979  --CSGHGFCIEG-----TCVCKKGW--KGADCGTMDKDALQCLPDCSGHGT---FDVDTQ 1026
              CS +  CI+      TCVC++GW   G DC  ++   L     C  + +         
Sbjct: 62   GGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQN 121

Query: 1027 TCSCHA--KWSGEDCSKEVCSLE----CGPHGRCVGE-----SCSCAAGWSGE 1068
             C C    + +G DC      LE    C P   C        SC C  G+ G+
Sbjct: 122  ECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGD 174



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 16/125 (12%)

Query: 1061 CAAGWSGEFCSVRLCDAR--CAEHGQCK---NGT--CLCVSGWNGRHCTL--EG-----C 1106
            C AG+ G  C     +A+  C  +G C    NGT  C C  G++G  C    EG     C
Sbjct: 521  CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 580

Query: 1107 PRSCAG-HGQCRVDNDGRWECKCFDGWDGPDC-TTLKEQICDDSRDNDKDGLVDCEDPEC 1164
             ++C+  HG+C     G   C C  GW G  C     E  C+ +     + L + +    
Sbjct: 581  DQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTAS 640

Query: 1165 CQSPA 1169
            C+  A
Sbjct: 641  CKCAA 645



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 45/171 (26%), Positives = 62/171 (36%), Gaps = 34/171 (19%)

Query: 979  CSGHGFC--IEGT--CVCKKGWKGAD--CGTMDKDALQCLPDCSGHGTF---DVDTQTCS 1029
            C  H  C    GT  C+CK G++G    C  MD         CS +         T TC 
Sbjct: 22   CHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCV 81

Query: 1030 CHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGT 1089
            C   W+G          +C     C+  S    AG   +       +A C   G  +N  
Sbjct: 82   CQQGWTGN-------GRDCSEINNCLLPS----AGGCHD-------NASCLYVGPGQN-E 122

Query: 1090 CLCVSGW--NGRHCT-LEGCPRS---CAGHGQCRVDNDGRWECKCFDGWDG 1134
            C C  G+  NG  C  +  C      C     C+  + G W C C +G++G
Sbjct: 123  CECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 173



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 13/75 (17%)

Query: 1079 CAEHGQCK--NGT--CLCVSGW--NGRHCT-LEGC----PRSCAGHGQCRVDNDGRWECK 1127
            C  H  C+  NGT  C+C +G+  +G  C+ ++ C    P  C+ + +C     G   C 
Sbjct: 22   CHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCV 81

Query: 1128 CFDGW--DGPDCTTL 1140
            C  GW  +G DC+ +
Sbjct: 82   CQQGWTGNGRDCSEI 96


>U77493-1|AAB19224.1|  263|Homo sapiens Notch2 protein.
          Length = 263

 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 73/259 (28%), Positives = 102/259 (39%), Gaps = 43/259 (16%)

Query: 919  YING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI 972
            Y+N   C+C  G+ G  C    +EC    C   G CV+G     C C  G+ G FC  EI
Sbjct: 1    YVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI 60

Query: 973  -DCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF--DVDT 1025
             +C    C   G C++G     C C  G+ G +C T+    L     C   GT      +
Sbjct: 61   NECSSHPCLNDGTCVDGLGTYRCSCPLGYTGKNCQTLVN--LCSRSPCKNKGTCVQKKAS 118

Query: 1026 QTCSCHAKWSGEDCSKEVCSLE-------------CGPHGRCVGES----CSCAAGWSGE 1068
              C C + W G  C     S +             C   G C+       C C  G++G 
Sbjct: 119  PQCLCPSGWVGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPVGYTGS 178

Query: 1069 FCSVRL--CDARCAEHG-QCKN----GTCLCVSGWNGRHCTLE--GCP-RSCAGHGQCRV 1118
            +C  +L  C +   +HG  C +      C CV G+ G +C  E   C  + C   G C +
Sbjct: 179  YCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC-I 237

Query: 1119 DNDGRWECKCFDGWDGPDC 1137
            D    ++C C  G  G  C
Sbjct: 238  DLVNHFKCSCPPGTRGLLC 256



 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 34/105 (32%), Positives = 48/105 (45%), Gaps = 15/105 (14%)

Query: 882 CSGKGECLMG----HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGW 930
           C   G C+      +CQC  G+ G  C + +  C     Q G    ++I G  C+C PG+
Sbjct: 154 CQHSGVCINAGNTHYCQCPVGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 213

Query: 931 KGKECSLRHDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGE 971
           +G  C    DEC+   C   G C+    + KCSC  G +G  C E
Sbjct: 214 QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEE 258



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 40/122 (32%), Positives = 56/122 (45%), Gaps = 14/122 (11%)

Query: 1058 SCSCAAGWSGEFC--SVRLC-DARCAEHGQCKNG----TCLCVSGWNGRHCTLE--GCP- 1107
            +C C AG+ G  C  ++  C ++ C   G C +G    +CLC  G+ G  C  E   C  
Sbjct: 6    TCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSS 65

Query: 1108 RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCE-DPEC-C 1165
              C   G C VD  G + C C  G+ G +C TL   +C  S   +K   V  +  P+C C
Sbjct: 66   HPCLNDGTC-VDGLGTYRCSCPLGYTGKNCQTL-VNLCSRSPCKNKGTCVQKKASPQCLC 123

Query: 1166 QS 1167
             S
Sbjct: 124  PS 125



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 12/91 (13%)

Query: 864 ISFVALVAEEMTHNCP-NGCSGKGEC---LMGH-CQCQPGFGGDDCSKSV--CPVLCSQR 916
           + +     EE    C  N C     C   + G+ C+C PG+ G +C   V  C     Q 
Sbjct: 173 VGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQN 232

Query: 917 G----EYING-ECQCNPGWKGKECSLRHDEC 942
           G    + +N  +C C PG +G  C    D+C
Sbjct: 233 GGTCIDLVNHFKCSCPPGTRGLLCEENIDDC 263


>AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein.
          Length = 2551

 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 73/250 (29%), Positives = 104/250 (41%), Gaps = 45/250 (18%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN-----GKCSCVRGYKGK 967
            C +R   +    +C  G+ G++C       + P CN  G C++     G+C C  G+ G 
Sbjct: 1937 CRERCSLVIQIPRCCKGYFGRDCQACPGGPDAP-CNNRGVCLDQYSATGECKCNTGFNGT 1995

Query: 968  FC-----GEI--DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDC 1015
             C     G    DC    CS HG C +G      C+C+ GW G  C T       C P C
Sbjct: 1996 ACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPC 2055

Query: 1016 SGHGTFDVDTQTCSCHAKWSGE--DCS-KEVCSLE---CGPHGRCVGE----SCSCAAGW 1065
            S H T   +  TC C+  + G+   C+  + C  +   C    RC  +    SCSC  G+
Sbjct: 2056 SAHATCK-ENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGY 2114

Query: 1066 SGE--FCS-VRLC----DARCAEHGQCK-----NGTCLCVSGW--NGRHCTLEGCP--RS 1109
             G+   C+ +  C    +  C EH  CK        C C S +  +G +C  E  P  R 
Sbjct: 2115 KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRC 2174

Query: 1110 CAGHGQCRVD 1119
               +GQC  D
Sbjct: 2175 LQDNGQCHAD 2184



 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 61/222 (27%), Positives = 89/222 (40%), Gaps = 39/222 (17%)

Query: 960  CVRGYKGKFCGEIDC-PHPTCSGHGFCIE-----GTCVCKKGWKGADC-----GTMDKDA 1008
            C +GY G+ C      P   C+  G C++     G C C  G+ G  C     G    D 
Sbjct: 1950 CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDC 2009

Query: 1009 LQCLPDCSGHGTFD---VDTQTCSCHAKWSGEDCSKE-----VCSLECGPHGRCV-GESC 1059
            L C   CS HG  D     +  C C   W+G  C  +     VC+  C  H  C    +C
Sbjct: 2010 LPC--GCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTC 2067

Query: 1060 SCAAGWSGE--FCSV-RLC---DARCAEHGQC-KNGT---CLCVSGW--NGRHCT----- 1102
             C   + G+   C+V   C   +  CA+  +C + GT   C C  G+  +G  CT     
Sbjct: 2068 ECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPC 2127

Query: 1103 LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQI 1144
             +G    C  H  C++   G+ +C+C   + G       EQ+
Sbjct: 2128 ADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQL 2169



 Score = 72.5 bits (170), Expect = 2e-11
 Identities = 69/228 (30%), Positives = 103/228 (45%), Gaps = 54/228 (23%)

Query: 960  CVRGYKGKFCGEIDCP---HPTCSGHGFCIE-----GTCVCKKGWKGAD---CGTMDKDA 1008
            C +G+ G  C +  CP      CSG+G C +     GTC+C++G++G+    C   +K  
Sbjct: 728  CCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785

Query: 1009 LQCLPDC-SGHGTFD--VDTQ----TCSCHAKWSGEDCSKEVCSLECGP-------HGRC 1054
             +C   C   HGT +  +D+     T +C    +G  C K+  +  CGP       H  C
Sbjct: 786  PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA--CGPYVQFCHIHATC 843

Query: 1055 V----GESCSCAAGWSGE--FCS-----VRLCDARCAEHGQC-KNG----TCLCVSGW-- 1096
                   SC C AG+ G+   CS       L    C+ + +C K G    TC+C  GW  
Sbjct: 844  EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTG 903

Query: 1097 NGRHCT-LEGC--PRS--CAGHGQCRVDNDGRWECKCFDGW--DGPDC 1137
            NGR C+ +  C  P +  C  +  C     G+ EC+C  G+  +G DC
Sbjct: 904  NGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDC 951



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 64/225 (28%), Positives = 87/225 (38%), Gaps = 42/225 (18%)

Query: 878  CPNG----CSGKGECL-----MGHCQCQPGFGGDDC--------SKSVCPVLCSQRGEYI 920
            CP G    C+ +G CL      G C+C  GF G  C             P  CS  G+  
Sbjct: 1962 CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCD 2021

Query: 921  -----NGECQCNPGWKGKECSLRHDECEV--PDCNGHGHC-VNGKCSCVRGYKGK--FCG 970
                 +G+C C  GW G  C  +     V  P C+ H  C  N  C C   Y+G    C 
Sbjct: 2022 DGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCT 2081

Query: 971  EID-CPHPT--CSGHGFCIE-GT---CVCKKGWK--GADCGTMDKDALQCLPDCSGHGTF 1021
             +D C      C+    C + GT   C C+KG+K  G  C  +D  A      C  H T 
Sbjct: 2082 VVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATC 2141

Query: 1022 DV---DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
             +       C C + + G+  +   C  E  P  RC+ ++  C A
Sbjct: 2142 KMTGPGKHKCECKSHYVGDGLN---CEPEQLPIDRCLQDNGQCHA 2183



 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 82/299 (27%), Positives = 116/299 (38%), Gaps = 67/299 (22%)

Query: 880  NGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV----LCSQRGEYI-----NGECQCNPGW 930
            +GC+      +   +C  GF G DC++  CP      CS  G+       NG C C  G+
Sbjct: 713  SGCARYCNATVKIPKCCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGF 770

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTC 990
            +G +C      C  P  N +G   N KC CV G        ID         G C+ GTC
Sbjct: 771  QGSQCQF----CSDP--NKYGPRCNKKCLCVHGTCNN---RID-------SDGACLTGTC 814

Query: 991  VCKKGWKGADCGTMDKDALQCLPD---CSGHGTFDVD--TQTCSCHAKWSGED--CSK-E 1042
              + G  G  C   DK    C P    C  H T +    T +C C A + G+   CS+ +
Sbjct: 815  --RDGSAGRLC---DKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMD 869

Query: 1043 VCSL----ECGPHGRCVG-----ESCSCAAGWSGEF--CS-VRLC----DARCAEHGQCK 1086
             C+      C  +  C+       +C C  GW+G    CS +  C       C ++  C 
Sbjct: 870  PCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCL 929

Query: 1087 -----NGTCLCVSGW--NGRHCT-LEGCPRS---CAGHGQCRVDNDGRWECKCFDGWDG 1134
                    C C  G+  NG  C  +  C      C     C+  + G W C C +G++G
Sbjct: 930  YVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988



 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 55/246 (22%)

Query: 878  CPNG----CSGKGECLMGH-----CQCQPGFGGDDCSKSV--------CPVLCS------ 914
            CP G    C+G+G C  G      C CQ GFGG  C            C  +C+      
Sbjct: 112  CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVC 171

Query: 915  QRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG-------KCSCVRGYK-- 965
              G   +G C+C   + G +C     EC    C  +  C          +C C+  Y+  
Sbjct: 172  NSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGD 231

Query: 966  GKFCGEID-CPHPTCSGHGFCI-----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGH 1018
            GK+C  I+ C    C  H  C        +C C++G++G     +  D  Q    +C   
Sbjct: 232  GKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTK 291

Query: 1019 GT---FDVDTQT-CSCHAKWS----GEDCS-KEVCSLE--CGPHGRCV----GES-CSCA 1062
             T   +D   Q+ C C   +     G  CS  ++C  +  C  +  C     G + C C 
Sbjct: 292  STVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQ 351

Query: 1063 AGWSGE 1068
             G+ G+
Sbjct: 352  KGYVGD 357



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 57/211 (27%), Positives = 80/211 (37%), Gaps = 47/211 (22%)

Query: 877  NCPNGCSGKGECL-----MGHCQCQPGFGGDDCSKSV-------CPVLCS------QRGE 918
            N  N C G G CL      G C+C  GF G  C           C   CS       +G 
Sbjct: 1351 NAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGP 1410

Query: 919  YINGECQCNPGWKGKEC--SLRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGK--FC 969
              +G C C+ GW+G  C  +   D C    C+   +C+        C C  G++G    C
Sbjct: 1411 LGDGSCDCDVGWRGVHCDNATTEDNCN-GTCHTSANCLTNSDGTASCKCAAGFQGNGTIC 1469

Query: 970  GEI---DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF 1021
              I   +  +  CS    C   T     C CK G+ G   G +  +   CL +  G    
Sbjct: 1470 TAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD--GIVCLEINPCLENHGGCDKN 1527

Query: 1022 DVDTQT------CSCHAKWSGEDCSKEVCSL 1046
               TQT      C+C   ++G+    +VC+L
Sbjct: 1528 AECTQTGPNQAACNCLPAYTGDG---KVCTL 1555



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 17/93 (18%)

Query: 1059 CSCAAGWSGEFCSVRL-------CDARCA-EHGQCK-----NGTCLCVSGWNGRHC---- 1101
            C C  G+SG  C           CD  C+  HG+C      +G+C C  GW G HC    
Sbjct: 1372 CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 1431

Query: 1102 TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
            T + C  +C     C  ++DG   CKC  G+ G
Sbjct: 1432 TEDNCNGTCHTSANCLTNSDGTASCKCAAGFQG 1464



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 51/158 (32%), Positives = 62/158 (39%), Gaps = 19/158 (12%)

Query: 989  TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLEC 1048
            +C    G K  D  TM       + DC    TF+V T + S         C K+     C
Sbjct: 45   SCALNLGVKCPDGYTMITSGSVGVRDC--RYTFEVRTYSLSLPG--CRHICRKDYLQPRC 100

Query: 1049 GPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHC------T 1102
             P GR  G  C    G +G  C+ R     CAE G   NGTC C  G+ G  C       
Sbjct: 101  CP-GRW-GPDCIECPGGAGSPCNGR---GSCAE-GMEGNGTCSCQEGFGGTACETCADDN 154

Query: 1103 LEG--CPRSC-AGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L G  C   C   HG C    DG   C+C+  + GP C
Sbjct: 155  LFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKC 192



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 59/211 (27%), Positives = 80/211 (37%), Gaps = 54/211 (25%)

Query: 960  CVRGYKGKFCGEIDCP---HPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQC 1011
            C  G+ G  C    CP      C G+G C++G      C C +G+ G  C T        
Sbjct: 1336 CCAGFFGPQCQP--CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET-------- 1385

Query: 1012 LPDCSGHGTFDVDT-QTCSC-HAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEF 1069
               C+  G + +   Q CSC H +     C++       GP G     SC C  GW G  
Sbjct: 1386 ---CT-EGKYGIHCDQACSCVHGR-----CNQ-------GPLG---DGSCDCDVGWRGVH 1426

Query: 1070 CSVRL----CDARCAEHGQC---KNGT--CLCVSGW--NGRHCT-LEGCPRS---CAGHG 1114
            C        C+  C     C    +GT  C C +G+  NG  CT +  C  S   C+   
Sbjct: 1427 CDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKA 1486

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQIC 1145
             C+    GR  C C  G+ G     L+   C
Sbjct: 1487 DCKRTTPGRRVCTCKAGYTGDGIVCLEINPC 1517



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 48/153 (31%), Positives = 62/153 (40%), Gaps = 33/153 (21%)

Query: 1014 DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVC--------SLECGPHGRC--VGESCSCAA 1063
            D SG     V+T +C    +WS     K+ C        +LE G   RC  V +   C  
Sbjct: 1897 DASGECGSCVNTPSCP---RWSKPKGVKQKCLYNLPFKRNLE-GCRERCSLVIQIPRCCK 1952

Query: 1064 GWSGEFCSVRLC----DARCAEHGQCKN-----GTCLCVSGWNGRHCTL--------EGC 1106
            G+ G  C    C    DA C   G C +     G C C +G+NG  C +        +  
Sbjct: 1953 GYFGRDCQA--CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCL 2010

Query: 1107 PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            P  C+ HGQC     G  +C C  GW GP C T
Sbjct: 2011 PCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT 2043



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 41/135 (30%), Positives = 55/135 (40%), Gaps = 21/135 (15%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV-------CP--VLCSQRGEYING-ECQC 926
           NC +G    G    G C+C   + G  C K +       CP    CS   E  N  EC+C
Sbjct: 165 NCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKC 224

Query: 927 NPGWK--GKECSLRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGKFCGEIDCPHPTC 979
            P ++  GK C    + C    C+ H HC         C+C  GY+G   G++  P   C
Sbjct: 225 LPNYRGDGKYCD-PINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGD--GQVCLPVDPC 281

Query: 980 S-GHGFCIEGTCVCK 993
               G C   + VCK
Sbjct: 282 QINFGNCPTKSTVCK 296



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 16/125 (12%)

Query: 1061 CAAGWSGEFCSVRLCDAR--CAEHGQCK---NGT--CLCVSGWNGRHCTL--EG-----C 1106
            C AG+ G  C     +A+  C  +G C    NGT  C C  G++G  C    EG     C
Sbjct: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 1395

Query: 1107 PRSCAG-HGQCRVDNDGRWECKCFDGWDGPDC-TTLKEQICDDSRDNDKDGLVDCEDPEC 1164
             ++C+  HG+C     G   C C  GW G  C     E  C+ +     + L + +    
Sbjct: 1396 DQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTAS 1455

Query: 1165 CQSPA 1169
            C+  A
Sbjct: 1456 CKCAA 1460



 Score = 37.9 bits (84), Expect = 0.55
 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 10/85 (11%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDG 1122
            +SG F S++   + CA +         C  G+ G  C     G    C+G+GQC     G
Sbjct: 704  YSGRFGSLK---SGCARYCNATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGG 760

Query: 1123 RWECKCFDGWDGPDCTTLKEQICDD 1147
               C C +G+ G  C     Q C D
Sbjct: 761  NGTCICEEGFQGSQC-----QFCSD 780


>AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for
            endocytosis precursor protein.
          Length = 1416

 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 73/250 (29%), Positives = 104/250 (41%), Gaps = 45/250 (18%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN-----GKCSCVRGYKGK 967
            C +R   +    +C  G+ G++C       + P CN  G C++     G+C C  G+ G 
Sbjct: 802  CRERCSLVIQIPRCCKGYFGRDCQACPGGPDAP-CNNRGVCLDQYSATGECKCNTGFNGT 860

Query: 968  FC-----GEI--DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDC 1015
             C     G    DC    CS HG C +G      C+C+ GW G  C T       C P C
Sbjct: 861  ACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPC 920

Query: 1016 SGHGTFDVDTQTCSCHAKWSGE--DCS-KEVCSLE---CGPHGRCVGE----SCSCAAGW 1065
            S H T   +  TC C+  + G+   C+  + C  +   C    RC  +    SCSC  G+
Sbjct: 921  SAHATCK-ENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGY 979

Query: 1066 SGE--FCS-VRLC----DARCAEHGQCK-----NGTCLCVSGW--NGRHCTLEGCP--RS 1109
             G+   C+ +  C    +  C EH  CK        C C S +  +G +C  E  P  R 
Sbjct: 980  KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRC 1039

Query: 1110 CAGHGQCRVD 1119
               +GQC  D
Sbjct: 1040 LQDNGQCHAD 1049



 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 61/222 (27%), Positives = 89/222 (40%), Gaps = 39/222 (17%)

Query: 960  CVRGYKGKFCGEIDC-PHPTCSGHGFCIE-----GTCVCKKGWKGADC-----GTMDKDA 1008
            C +GY G+ C      P   C+  G C++     G C C  G+ G  C     G    D 
Sbjct: 815  CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDC 874

Query: 1009 LQCLPDCSGHGTFD---VDTQTCSCHAKWSGEDCSKE-----VCSLECGPHGRCV-GESC 1059
            L C   CS HG  D     +  C C   W+G  C  +     VC+  C  H  C    +C
Sbjct: 875  LPC--GCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTC 932

Query: 1060 SCAAGWSGE--FCSV-RLC---DARCAEHGQC-KNGT---CLCVSGW--NGRHCT----- 1102
             C   + G+   C+V   C   +  CA+  +C + GT   C C  G+  +G  CT     
Sbjct: 933  ECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPC 992

Query: 1103 LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQI 1144
             +G    C  H  C++   G+ +C+C   + G       EQ+
Sbjct: 993  ADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQL 1034



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 64/225 (28%), Positives = 87/225 (38%), Gaps = 42/225 (18%)

Query: 878  CPNG----CSGKGECL-----MGHCQCQPGFGGDDC--------SKSVCPVLCSQRGEYI 920
            CP G    C+ +G CL      G C+C  GF G  C             P  CS  G+  
Sbjct: 827  CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCD 886

Query: 921  -----NGECQCNPGWKGKECSLRHDECEV--PDCNGHGHC-VNGKCSCVRGYKGK--FCG 970
                 +G+C C  GW G  C  +     V  P C+ H  C  N  C C   Y+G    C 
Sbjct: 887  DGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCT 946

Query: 971  EID-CPHPT--CSGHGFCIE-GT---CVCKKGWK--GADCGTMDKDALQCLPDCSGHGTF 1021
             +D C      C+    C + GT   C C+KG+K  G  C  +D  A      C  H T 
Sbjct: 947  VVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATC 1006

Query: 1022 DV---DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
             +       C C + + G+  +   C  E  P  RC+ ++  C A
Sbjct: 1007 KMTGPGKHKCECKSHYVGDGLN---CEPEQLPIDRCLQDNGQCHA 1048



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 57/211 (27%), Positives = 80/211 (37%), Gaps = 47/211 (22%)

Query: 877  NCPNGCSGKGECL-----MGHCQCQPGFGGDDCSKSV-------CPVLCS------QRGE 918
            N  N C G G CL      G C+C  GF G  C           C   CS       +G 
Sbjct: 216  NAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGP 275

Query: 919  YINGECQCNPGWKGKEC--SLRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGK--FC 969
              +G C C+ GW+G  C  +   D C    C+   +C+        C C  G++G    C
Sbjct: 276  LGDGSCDCDVGWRGVHCDNATTEDNCN-GTCHTSANCLTNSDGTASCKCAAGFQGNGTIC 334

Query: 970  GEI---DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF 1021
              I   +  +  CS    C   T     C CK G+ G   G +  +   CL +  G    
Sbjct: 335  TAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD--GIVCLEINPCLENHGGCDKN 392

Query: 1022 DVDTQT------CSCHAKWSGEDCSKEVCSL 1046
               TQT      C+C   ++G+    +VC+L
Sbjct: 393  AECTQTGPNQAACNCLPAYTGDG---KVCTL 420



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 17/93 (18%)

Query: 1059 CSCAAGWSGEFCSVRL-------CDARCA-EHGQCK-----NGTCLCVSGWNGRHC---- 1101
            C C  G+SG  C           CD  C+  HG+C      +G+C C  GW G HC    
Sbjct: 237  CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 296

Query: 1102 TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
            T + C  +C     C  ++DG   CKC  G+ G
Sbjct: 297  TEDNCNGTCHTSANCLTNSDGTASCKCAAGFQG 329



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 59/211 (27%), Positives = 80/211 (37%), Gaps = 54/211 (25%)

Query: 960  CVRGYKGKFCGEIDCP---HPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQC 1011
            C  G+ G  C    CP      C G+G C++G      C C +G+ G  C T        
Sbjct: 201  CCAGFFGPQCQP--CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET-------- 250

Query: 1012 LPDCSGHGTFDVDT-QTCSC-HAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEF 1069
               C+  G + +   Q CSC H +     C++       GP G     SC C  GW G  
Sbjct: 251  ---CT-EGKYGIHCDQACSCVHGR-----CNQ-------GPLG---DGSCDCDVGWRGVH 291

Query: 1070 CSVRL----CDARCAEHGQC---KNGT--CLCVSGW--NGRHCT-LEGCPRS---CAGHG 1114
            C        C+  C     C    +GT  C C +G+  NG  CT +  C  S   C+   
Sbjct: 292  CDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKA 351

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQIC 1145
             C+    GR  C C  G+ G     L+   C
Sbjct: 352  DCKRTTPGRRVCTCKAGYTGDGIVCLEINPC 382



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 48/153 (31%), Positives = 62/153 (40%), Gaps = 33/153 (21%)

Query: 1014 DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVC--------SLECGPHGRC--VGESCSCAA 1063
            D SG     V+T +C    +WS     K+ C        +LE G   RC  V +   C  
Sbjct: 762  DASGECGSCVNTPSCP---RWSKPKGVKQKCLYNLPFKRNLE-GCRERCSLVIQIPRCCK 817

Query: 1064 GWSGEFCSVRLC----DARCAEHGQCKN-----GTCLCVSGWNGRHCTL--------EGC 1106
            G+ G  C    C    DA C   G C +     G C C +G+NG  C +        +  
Sbjct: 818  GYFGRDCQA--CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCL 875

Query: 1107 PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            P  C+ HGQC     G  +C C  GW GP C T
Sbjct: 876  PCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT 908



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 16/125 (12%)

Query: 1061 CAAGWSGEFCSVRLCDAR--CAEHGQCK---NGT--CLCVSGWNGRHCTL--EG-----C 1106
            C AG+ G  C     +A+  C  +G C    NGT  C C  G++G  C    EG     C
Sbjct: 201  CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 260

Query: 1107 PRSCAG-HGQCRVDNDGRWECKCFDGWDGPDC-TTLKEQICDDSRDNDKDGLVDCEDPEC 1164
             ++C+  HG+C     G   C C  GW G  C     E  C+ +     + L + +    
Sbjct: 261  DQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTAS 320

Query: 1165 CQSPA 1169
            C+  A
Sbjct: 321  CKCAA 325


>AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein.
          Length = 1192

 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 73/250 (29%), Positives = 104/250 (41%), Gaps = 45/250 (18%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN-----GKCSCVRGYKGK 967
            C +R   +    +C  G+ G++C       + P CN  G C++     G+C C  G+ G 
Sbjct: 578  CRERCSLVIQIPRCCKGYFGRDCQACPGGPDAP-CNNRGVCLDQYSATGECKCNTGFNGT 636

Query: 968  FC-----GEI--DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDC 1015
             C     G    DC    CS HG C +G      C+C+ GW G  C T       C P C
Sbjct: 637  ACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPC 696

Query: 1016 SGHGTFDVDTQTCSCHAKWSGE--DCS-KEVCSLE---CGPHGRCVGE----SCSCAAGW 1065
            S H T   +  TC C+  + G+   C+  + C  +   C    RC  +    SCSC  G+
Sbjct: 697  SAHATCK-ENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGY 755

Query: 1066 SGE--FCS-VRLC----DARCAEHGQCK-----NGTCLCVSGW--NGRHCTLEGCP--RS 1109
             G+   C+ +  C    +  C EH  CK        C C S +  +G +C  E  P  R 
Sbjct: 756  KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRC 815

Query: 1110 CAGHGQCRVD 1119
               +GQC  D
Sbjct: 816  LQDNGQCHAD 825



 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 61/222 (27%), Positives = 89/222 (40%), Gaps = 39/222 (17%)

Query: 960  CVRGYKGKFCGEIDC-PHPTCSGHGFCIE-----GTCVCKKGWKGADC-----GTMDKDA 1008
            C +GY G+ C      P   C+  G C++     G C C  G+ G  C     G    D 
Sbjct: 591  CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDC 650

Query: 1009 LQCLPDCSGHGTFD---VDTQTCSCHAKWSGEDCSKE-----VCSLECGPHGRCV-GESC 1059
            L C   CS HG  D     +  C C   W+G  C  +     VC+  C  H  C    +C
Sbjct: 651  LPC--GCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTC 708

Query: 1060 SCAAGWSGE--FCSV-RLC---DARCAEHGQC-KNGT---CLCVSGW--NGRHCT----- 1102
             C   + G+   C+V   C   +  CA+  +C + GT   C C  G+  +G  CT     
Sbjct: 709  ECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPC 768

Query: 1103 LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQI 1144
             +G    C  H  C++   G+ +C+C   + G       EQ+
Sbjct: 769  ADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQL 810



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 64/225 (28%), Positives = 87/225 (38%), Gaps = 42/225 (18%)

Query: 878  CPNG----CSGKGECL-----MGHCQCQPGFGGDDC--------SKSVCPVLCSQRGEYI 920
            CP G    C+ +G CL      G C+C  GF G  C             P  CS  G+  
Sbjct: 603  CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCD 662

Query: 921  -----NGECQCNPGWKGKECSLRHDECEV--PDCNGHGHC-VNGKCSCVRGYKGK--FCG 970
                 +G+C C  GW G  C  +     V  P C+ H  C  N  C C   Y+G    C 
Sbjct: 663  DGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCT 722

Query: 971  EID-CPHPT--CSGHGFCIE-GT---CVCKKGWK--GADCGTMDKDALQCLPDCSGHGTF 1021
             +D C      C+    C + GT   C C+KG+K  G  C  +D  A      C  H T 
Sbjct: 723  VVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATC 782

Query: 1022 DV---DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
             +       C C + + G+  +   C  E  P  RC+ ++  C A
Sbjct: 783  KMTGPGKHKCECKSHYVGDGLN---CEPEQLPIDRCLQDNGQCHA 824



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 17/93 (18%)

Query: 1059 CSCAAGWSGEFCSVRL-------CDARCA-EHGQCK-----NGTCLCVSGWNGRHC---- 1101
            C C  G+SG  C           CD  C+  HG+C      +G+C C  GW G HC    
Sbjct: 13   CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 72

Query: 1102 TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
            T + C  +C     C  ++DG   CKC  G+ G
Sbjct: 73   TEDNCNGTCHTSANCLTNSDGTASCKCAAGFQG 105



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 48/153 (31%), Positives = 62/153 (40%), Gaps = 33/153 (21%)

Query: 1014 DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVC--------SLECGPHGRC--VGESCSCAA 1063
            D SG     V+T +C    +WS     K+ C        +LE G   RC  V +   C  
Sbjct: 538  DASGECGSCVNTPSCP---RWSKPKGVKQKCLYNLPFKRNLE-GCRERCSLVIQIPRCCK 593

Query: 1064 GWSGEFCSVRLC----DARCAEHGQCKN-----GTCLCVSGWNGRHCTL--------EGC 1106
            G+ G  C    C    DA C   G C +     G C C +G+NG  C +        +  
Sbjct: 594  GYFGRDCQA--CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCL 651

Query: 1107 PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            P  C+ HGQC     G  +C C  GW GP C T
Sbjct: 652  PCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT 684



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 44/149 (29%), Positives = 59/149 (39%), Gaps = 28/149 (18%)

Query: 1025 TQTCSCHAKWSG---EDCSKEVCSLECGP-----HGRC----VGE-SCSCAAGWSGEFCS 1071
            T  C C   +SG   E C++    + C       HGRC    +G+ SC C  GW G  C 
Sbjct: 10   TGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCD 69

Query: 1072 VRL----CDARCAEHGQC---KNGT--CLCVSGW--NGRHCT-LEGCPRS---CAGHGQC 1116
                   C+  C     C    +GT  C C +G+  NG  CT +  C  S   C+    C
Sbjct: 70   NATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADC 129

Query: 1117 RVDNDGRWECKCFDGWDGPDCTTLKEQIC 1145
            +    GR  C C  G+ G     L+   C
Sbjct: 130  KRTTPGRRVCTCKAGYTGDGIVCLEINPC 158



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 50/192 (26%), Positives = 73/192 (38%), Gaps = 42/192 (21%)

Query: 891  GHCQCQPGFGGDDCSKSV-------CPVLCS------QRGEYINGECQCNPGWKGKEC-- 935
            G C+C  GF G  C           C   CS       +G   +G C C+ GW+G  C  
Sbjct: 11   GVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDN 70

Query: 936  SLRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGK--FCGEI---DCPHPTCSGHGFC 985
            +   D C    C+   +C+        C C  G++G    C  I   +  +  CS    C
Sbjct: 71   ATTEDNCN-GTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADC 129

Query: 986  IEGT-----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT------CSCHAKW 1034
               T     C CK G+ G   G +  +   CL +  G       TQT      C+C   +
Sbjct: 130  KRTTPGRRVCTCKAGYTGD--GIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAY 187

Query: 1035 SGEDCSKEVCSL 1046
            +G+    +VC+L
Sbjct: 188  TGDG---KVCTL 196



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 25/91 (27%), Positives = 37/91 (40%), Gaps = 9/91 (9%)

Query: 1088 GTCLCVSGWNGRHCTL--EG-----CPRSCAG-HGQCRVDNDGRWECKCFDGWDGPDC-T 1138
            G C C  G++G  C    EG     C ++C+  HG+C     G   C C  GW G  C  
Sbjct: 11   GVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDN 70

Query: 1139 TLKEQICDDSRDNDKDGLVDCEDPECCQSPA 1169
               E  C+ +     + L + +    C+  A
Sbjct: 71   ATTEDNCNGTCHTSANCLTNSDGTASCKCAA 101


>AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein.
          Length = 2551

 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 73/250 (29%), Positives = 104/250 (41%), Gaps = 45/250 (18%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN-----GKCSCVRGYKGK 967
            C +R   +    +C  G+ G++C       + P CN  G C++     G+C C  G+ G 
Sbjct: 1937 CRERCSLVIQIPRCCKGYFGRDCQACPGGPDAP-CNNRGVCLDQYSATGECKCNTGFNGT 1995

Query: 968  FC-----GEI--DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDC 1015
             C     G    DC    CS HG C +G      C+C+ GW G  C T       C P C
Sbjct: 1996 ACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPC 2055

Query: 1016 SGHGTFDVDTQTCSCHAKWSGE--DCS-KEVCSLE---CGPHGRCVGE----SCSCAAGW 1065
            S H T   +  TC C+  + G+   C+  + C  +   C    RC  +    SCSC  G+
Sbjct: 2056 SAHATCK-ENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGY 2114

Query: 1066 SGE--FCS-VRLC----DARCAEHGQCK-----NGTCLCVSGW--NGRHCTLEGCP--RS 1109
             G+   C+ +  C    +  C EH  CK        C C S +  +G +C  E  P  R 
Sbjct: 2115 KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRC 2174

Query: 1110 CAGHGQCRVD 1119
               +GQC  D
Sbjct: 2175 LQDNGQCHAD 2184



 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 61/222 (27%), Positives = 89/222 (40%), Gaps = 39/222 (17%)

Query: 960  CVRGYKGKFCGEIDC-PHPTCSGHGFCIE-----GTCVCKKGWKGADC-----GTMDKDA 1008
            C +GY G+ C      P   C+  G C++     G C C  G+ G  C     G    D 
Sbjct: 1950 CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDC 2009

Query: 1009 LQCLPDCSGHGTFD---VDTQTCSCHAKWSGEDCSKE-----VCSLECGPHGRCV-GESC 1059
            L C   CS HG  D     +  C C   W+G  C  +     VC+  C  H  C    +C
Sbjct: 2010 LPC--GCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTC 2067

Query: 1060 SCAAGWSGE--FCSV-RLC---DARCAEHGQC-KNGT---CLCVSGW--NGRHCT----- 1102
             C   + G+   C+V   C   +  CA+  +C + GT   C C  G+  +G  CT     
Sbjct: 2068 ECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPC 2127

Query: 1103 LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQI 1144
             +G    C  H  C++   G+ +C+C   + G       EQ+
Sbjct: 2128 ADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQL 2169



 Score = 72.5 bits (170), Expect = 2e-11
 Identities = 69/228 (30%), Positives = 103/228 (45%), Gaps = 54/228 (23%)

Query: 960  CVRGYKGKFCGEIDCP---HPTCSGHGFCIE-----GTCVCKKGWKGAD---CGTMDKDA 1008
            C +G+ G  C +  CP      CSG+G C +     GTC+C++G++G+    C   +K  
Sbjct: 728  CCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785

Query: 1009 LQCLPDC-SGHGTFD--VDTQ----TCSCHAKWSGEDCSKEVCSLECGP-------HGRC 1054
             +C   C   HGT +  +D+     T +C    +G  C K+  +  CGP       H  C
Sbjct: 786  PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA--CGPYVQFCHIHATC 843

Query: 1055 V----GESCSCAAGWSGE--FCS-----VRLCDARCAEHGQC-KNG----TCLCVSGW-- 1096
                   SC C AG+ G+   CS       L    C+ + +C K G    TC+C  GW  
Sbjct: 844  EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTG 903

Query: 1097 NGRHCT-LEGC--PRS--CAGHGQCRVDNDGRWECKCFDGW--DGPDC 1137
            NGR C+ +  C  P +  C  +  C     G+ EC+C  G+  +G DC
Sbjct: 904  NGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDC 951



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 64/225 (28%), Positives = 87/225 (38%), Gaps = 42/225 (18%)

Query: 878  CPNG----CSGKGECL-----MGHCQCQPGFGGDDC--------SKSVCPVLCSQRGEYI 920
            CP G    C+ +G CL      G C+C  GF G  C             P  CS  G+  
Sbjct: 1962 CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCD 2021

Query: 921  -----NGECQCNPGWKGKECSLRHDECEV--PDCNGHGHC-VNGKCSCVRGYKGK--FCG 970
                 +G+C C  GW G  C  +     V  P C+ H  C  N  C C   Y+G    C 
Sbjct: 2022 DGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCT 2081

Query: 971  EID-CPHPT--CSGHGFCIE-GT---CVCKKGWK--GADCGTMDKDALQCLPDCSGHGTF 1021
             +D C      C+    C + GT   C C+KG+K  G  C  +D  A      C  H T 
Sbjct: 2082 VVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATC 2141

Query: 1022 DV---DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
             +       C C + + G+  +   C  E  P  RC+ ++  C A
Sbjct: 2142 KMTGPGKHKCECKSHYVGDGLN---CEPEQLPIDRCLQDNGQCHA 2183



 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 82/299 (27%), Positives = 116/299 (38%), Gaps = 67/299 (22%)

Query: 880  NGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV----LCSQRGEYI-----NGECQCNPGW 930
            +GC+      +   +C  GF G DC++  CP      CS  G+       NG C C  G+
Sbjct: 713  SGCARYCNATVKIPKCCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGF 770

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTC 990
            +G +C      C  P  N +G   N KC CV G        ID         G C+ GTC
Sbjct: 771  QGSQCQF----CSDP--NKYGPRCNKKCLCVHGTCNN---RID-------SDGACLTGTC 814

Query: 991  VCKKGWKGADCGTMDKDALQCLPD---CSGHGTFDVD--TQTCSCHAKWSGED--CSK-E 1042
              + G  G  C   DK    C P    C  H T +    T +C C A + G+   CS+ +
Sbjct: 815  --RDGSAGRLC---DKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMD 869

Query: 1043 VCSL----ECGPHGRCVG-----ESCSCAAGWSGEF--CS-VRLC----DARCAEHGQCK 1086
             C+      C  +  C+       +C C  GW+G    CS +  C       C ++  C 
Sbjct: 870  PCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCL 929

Query: 1087 -----NGTCLCVSGW--NGRHCT-LEGCPRS---CAGHGQCRVDNDGRWECKCFDGWDG 1134
                    C C  G+  NG  C  +  C      C     C+  + G W C C +G++G
Sbjct: 930  YVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988



 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 55/246 (22%)

Query: 878  CPNG----CSGKGECLMGH-----CQCQPGFGGDDCSKSV--------CPVLCS------ 914
            CP G    C+G+G C  G      C CQ GFGG  C            C  +C+      
Sbjct: 112  CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVC 171

Query: 915  QRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG-------KCSCVRGYK-- 965
              G   +G C+C   + G +C     EC    C  +  C          +C C+  Y+  
Sbjct: 172  NSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGD 231

Query: 966  GKFCGEID-CPHPTCSGHGFCI-----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGH 1018
            GK+C  I+ C    C  H  C        +C C++G++G     +  D  Q    +C   
Sbjct: 232  GKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTK 291

Query: 1019 GT---FDVDTQT-CSCHAKWS----GEDCS-KEVCSLE--CGPHGRCV----GES-CSCA 1062
             T   +D   Q+ C C   +     G  CS  ++C  +  C  +  C     G + C C 
Sbjct: 292  STVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQ 351

Query: 1063 AGWSGE 1068
             G+ G+
Sbjct: 352  KGYVGD 357



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 57/211 (27%), Positives = 80/211 (37%), Gaps = 47/211 (22%)

Query: 877  NCPNGCSGKGECL-----MGHCQCQPGFGGDDCSKSV-------CPVLCS------QRGE 918
            N  N C G G CL      G C+C  GF G  C           C   CS       +G 
Sbjct: 1351 NAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGP 1410

Query: 919  YINGECQCNPGWKGKEC--SLRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGK--FC 969
              +G C C+ GW+G  C  +   D C    C+   +C+        C C  G++G    C
Sbjct: 1411 LGDGSCDCDVGWRGVHCDNATTEDNCN-GTCHTSANCLTNSDGTASCKCAAGFQGNGTIC 1469

Query: 970  GEI---DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF 1021
              I   +  +  CS    C   T     C CK G+ G   G +  +   CL +  G    
Sbjct: 1470 TAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD--GIVCLEINPCLENHGGCDKN 1527

Query: 1022 DVDTQT------CSCHAKWSGEDCSKEVCSL 1046
               TQT      C+C   ++G+    +VC+L
Sbjct: 1528 AECTQTGPNQAACNCLPAYTGDG---KVCTL 1555



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 17/93 (18%)

Query: 1059 CSCAAGWSGEFCSVRL-------CDARCA-EHGQCK-----NGTCLCVSGWNGRHC---- 1101
            C C  G+SG  C           CD  C+  HG+C      +G+C C  GW G HC    
Sbjct: 1372 CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 1431

Query: 1102 TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
            T + C  +C     C  ++DG   CKC  G+ G
Sbjct: 1432 TEDNCNGTCHTSANCLTNSDGTASCKCAAGFQG 1464



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 51/158 (32%), Positives = 62/158 (39%), Gaps = 19/158 (12%)

Query: 989  TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLEC 1048
            +C    G K  D  TM       + DC    TF+V T + S         C K+     C
Sbjct: 45   SCALNLGVKCPDGYTMITSGSVGVRDC--RYTFEVRTYSLSLPG--CRHICRKDYLQPRC 100

Query: 1049 GPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHC------T 1102
             P GR  G  C    G +G  C+ R     CAE G   NGTC C  G+ G  C       
Sbjct: 101  CP-GRW-GPDCIECPGGAGSPCNGR---GSCAE-GMEGNGTCSCQEGFGGTACETCADDN 154

Query: 1103 LEG--CPRSC-AGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L G  C   C   HG C    DG   C+C+  + GP C
Sbjct: 155  LFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKC 192



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 59/211 (27%), Positives = 80/211 (37%), Gaps = 54/211 (25%)

Query: 960  CVRGYKGKFCGEIDCP---HPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQC 1011
            C  G+ G  C    CP      C G+G C++G      C C +G+ G  C T        
Sbjct: 1336 CCAGFFGPQCQP--CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET-------- 1385

Query: 1012 LPDCSGHGTFDVDT-QTCSC-HAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEF 1069
               C+  G + +   Q CSC H +     C++       GP G     SC C  GW G  
Sbjct: 1386 ---CT-EGKYGIHCDQACSCVHGR-----CNQ-------GPLG---DGSCDCDVGWRGVH 1426

Query: 1070 CSVRL----CDARCAEHGQC---KNGT--CLCVSGW--NGRHCT-LEGCPRS---CAGHG 1114
            C        C+  C     C    +GT  C C +G+  NG  CT +  C  S   C+   
Sbjct: 1427 CDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKA 1486

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQIC 1145
             C+    GR  C C  G+ G     L+   C
Sbjct: 1487 DCKRTTPGRRVCTCKAGYTGDGIVCLEINPC 1517



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 48/153 (31%), Positives = 62/153 (40%), Gaps = 33/153 (21%)

Query: 1014 DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVC--------SLECGPHGRC--VGESCSCAA 1063
            D SG     V+T +C    +WS     K+ C        +LE G   RC  V +   C  
Sbjct: 1897 DASGECGSCVNTPSCP---RWSKPKGVKQKCLYNLPFKRNLE-GCRERCSLVIQIPRCCK 1952

Query: 1064 GWSGEFCSVRLC----DARCAEHGQCKN-----GTCLCVSGWNGRHCTL--------EGC 1106
            G+ G  C    C    DA C   G C +     G C C +G+NG  C +        +  
Sbjct: 1953 GYFGRDCQA--CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCL 2010

Query: 1107 PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            P  C+ HGQC     G  +C C  GW GP C T
Sbjct: 2011 PCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT 2043



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 41/135 (30%), Positives = 55/135 (40%), Gaps = 21/135 (15%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV-------CP--VLCSQRGEYING-ECQC 926
           NC +G    G    G C+C   + G  C K +       CP    CS   E  N  EC+C
Sbjct: 165 NCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKC 224

Query: 927 NPGWK--GKECSLRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGKFCGEIDCPHPTC 979
            P ++  GK C    + C    C+ H HC         C+C  GY+G   G++  P   C
Sbjct: 225 LPNYRGDGKYCD-PINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGD--GQVCLPVDPC 281

Query: 980 S-GHGFCIEGTCVCK 993
               G C   + VCK
Sbjct: 282 QINFGNCPTKSTVCK 296



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 16/125 (12%)

Query: 1061 CAAGWSGEFCSVRLCDAR--CAEHGQCK---NGT--CLCVSGWNGRHCTL--EG-----C 1106
            C AG+ G  C     +A+  C  +G C    NGT  C C  G++G  C    EG     C
Sbjct: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 1395

Query: 1107 PRSCAG-HGQCRVDNDGRWECKCFDGWDGPDC-TTLKEQICDDSRDNDKDGLVDCEDPEC 1164
             ++C+  HG+C     G   C C  GW G  C     E  C+ +     + L + +    
Sbjct: 1396 DQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTAS 1455

Query: 1165 CQSPA 1169
            C+  A
Sbjct: 1456 CKCAA 1460



 Score = 37.9 bits (84), Expect = 0.55
 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 10/85 (11%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDG 1122
            +SG F S++   + CA +         C  G+ G  C     G    C+G+GQC     G
Sbjct: 704  YSGRFGSLK---SGCARYCNATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGG 760

Query: 1123 RWECKCFDGWDGPDCTTLKEQICDD 1147
               C C +G+ G  C     Q C D
Sbjct: 761  NGTCICEEGFQGSQC-----QFCSD 780


>AF160476-1|AAF82398.1|  897|Homo sapiens CD44-like precursor FELL
            protein.
          Length = 897

 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 73/250 (29%), Positives = 104/250 (41%), Gaps = 45/250 (18%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN-----GKCSCVRGYKGK 967
            C +R   +    +C  G+ G++C       + P CN  G C++     G+C C  G+ G 
Sbjct: 283  CRERCSLVIQIPRCCKGYFGRDCQACPGGPDAP-CNNRGVCLDQYSATGECKCNTGFNGT 341

Query: 968  FC-----GEI--DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDC 1015
             C     G    DC    CS HG C +G      C+C+ GW G  C T       C P C
Sbjct: 342  ACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPC 401

Query: 1016 SGHGTFDVDTQTCSCHAKWSGE--DCS-KEVCSLE---CGPHGRCVGE----SCSCAAGW 1065
            S H T   +  TC C+  + G+   C+  + C  +   C    RC  +    SCSC  G+
Sbjct: 402  SAHATCK-ENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGY 460

Query: 1066 SGE--FCS-VRLC----DARCAEHGQCK-----NGTCLCVSGW--NGRHCTLEGCP--RS 1109
             G+   C+ +  C    +  C EH  CK        C C S +  +G +C  E  P  R 
Sbjct: 461  KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRC 520

Query: 1110 CAGHGQCRVD 1119
               +GQC  D
Sbjct: 521  LQDNGQCHAD 530



 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 61/222 (27%), Positives = 89/222 (40%), Gaps = 39/222 (17%)

Query: 960  CVRGYKGKFCGEIDC-PHPTCSGHGFCIE-----GTCVCKKGWKGADC-----GTMDKDA 1008
            C +GY G+ C      P   C+  G C++     G C C  G+ G  C     G    D 
Sbjct: 296  CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDC 355

Query: 1009 LQCLPDCSGHGTFD---VDTQTCSCHAKWSGEDCSKE-----VCSLECGPHGRCV-GESC 1059
            L C   CS HG  D     +  C C   W+G  C  +     VC+  C  H  C    +C
Sbjct: 356  LPC--GCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTC 413

Query: 1060 SCAAGWSGE--FCSV-RLC---DARCAEHGQC-KNGT---CLCVSGW--NGRHCT----- 1102
             C   + G+   C+V   C   +  CA+  +C + GT   C C  G+  +G  CT     
Sbjct: 414  ECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPC 473

Query: 1103 LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQI 1144
             +G    C  H  C++   G+ +C+C   + G       EQ+
Sbjct: 474  ADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQL 515



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 64/225 (28%), Positives = 87/225 (38%), Gaps = 42/225 (18%)

Query: 878  CPNG----CSGKGECL-----MGHCQCQPGFGGDDC--------SKSVCPVLCSQRGEYI 920
            CP G    C+ +G CL      G C+C  GF G  C             P  CS  G+  
Sbjct: 308  CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCD 367

Query: 921  -----NGECQCNPGWKGKECSLRHDECEV--PDCNGHGHC-VNGKCSCVRGYKGK--FCG 970
                 +G+C C  GW G  C  +     V  P C+ H  C  N  C C   Y+G    C 
Sbjct: 368  DGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCT 427

Query: 971  EID-CPHPT--CSGHGFCIE-GT---CVCKKGWK--GADCGTMDKDALQCLPDCSGHGTF 1021
             +D C      C+    C + GT   C C+KG+K  G  C  +D  A      C  H T 
Sbjct: 428  VVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATC 487

Query: 1022 DV---DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
             +       C C + + G+  +   C  E  P  RC+ ++  C A
Sbjct: 488  KMTGPGKHKCECKSHYVGDGLN---CEPEQLPIDRCLQDNGQCHA 529



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 48/153 (31%), Positives = 62/153 (40%), Gaps = 33/153 (21%)

Query: 1014 DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVC--------SLECGPHGRC--VGESCSCAA 1063
            D SG     V+T +C    +WS     K+ C        +LE G   RC  V +   C  
Sbjct: 243  DASGECGSCVNTPSCP---RWSKPKGVKQKCLYNLPFKRNLE-GCRERCSLVIQIPRCCK 298

Query: 1064 GWSGEFCSVRLC----DARCAEHGQCKN-----GTCLCVSGWNGRHCTL--------EGC 1106
            G+ G  C    C    DA C   G C +     G C C +G+NG  C +        +  
Sbjct: 299  GYFGRDCQA--CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCL 356

Query: 1107 PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            P  C+ HGQC     G  +C C  GW GP C T
Sbjct: 357  PCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT 389


>AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein.
          Length = 2551

 Score = 87.8 bits (208), Expect = 5e-16
 Identities = 73/250 (29%), Positives = 104/250 (41%), Gaps = 45/250 (18%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN-----GKCSCVRGYKGK 967
            C +R   +    +C  G+ G++C       + P CN  G C++     G+C C  G+ G 
Sbjct: 1937 CRERCSLVIQIPRCCKGYFGRDCQACPGGPDAP-CNNRGVCLDQYSATGECKCNTGFNGT 1995

Query: 968  FC-----GEI--DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDC 1015
             C     G    DC    CS HG C +G      C+C+ GW G  C T       C P C
Sbjct: 1996 ACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPC 2055

Query: 1016 SGHGTFDVDTQTCSCHAKWSGE--DCS-KEVCSLE---CGPHGRCVGE----SCSCAAGW 1065
            S H T   +  TC C+  + G+   C+  + C  +   C    RC  +    SCSC  G+
Sbjct: 2056 SAHATCK-ENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGY 2114

Query: 1066 SGE--FCS-VRLC----DARCAEHGQCK-----NGTCLCVSGW--NGRHCTLEGCP--RS 1109
             G+   C+ +  C    +  C EH  CK        C C S +  +G +C  E  P  R 
Sbjct: 2115 KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRC 2174

Query: 1110 CAGHGQCRVD 1119
               +GQC  D
Sbjct: 2175 LQDNGQCHAD 2184



 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 61/222 (27%), Positives = 89/222 (40%), Gaps = 39/222 (17%)

Query: 960  CVRGYKGKFCGEIDC-PHPTCSGHGFCIE-----GTCVCKKGWKGADC-----GTMDKDA 1008
            C +GY G+ C      P   C+  G C++     G C C  G+ G  C     G    D 
Sbjct: 1950 CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDC 2009

Query: 1009 LQCLPDCSGHGTFD---VDTQTCSCHAKWSGEDCSKE-----VCSLECGPHGRCV-GESC 1059
            L C   CS HG  D     +  C C   W+G  C  +     VC+  C  H  C    +C
Sbjct: 2010 LPC--GCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTC 2067

Query: 1060 SCAAGWSGE--FCSV-RLC---DARCAEHGQC-KNGT---CLCVSGW--NGRHCT----- 1102
             C   + G+   C+V   C   +  CA+  +C + GT   C C  G+  +G  CT     
Sbjct: 2068 ECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPC 2127

Query: 1103 LEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQI 1144
             +G    C  H  C++   G+ +C+C   + G       EQ+
Sbjct: 2128 ADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQL 2169



 Score = 72.5 bits (170), Expect = 2e-11
 Identities = 69/228 (30%), Positives = 103/228 (45%), Gaps = 54/228 (23%)

Query: 960  CVRGYKGKFCGEIDCP---HPTCSGHGFCIE-----GTCVCKKGWKGAD---CGTMDKDA 1008
            C +G+ G  C +  CP      CSG+G C +     GTC+C++G++G+    C   +K  
Sbjct: 728  CCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785

Query: 1009 LQCLPDC-SGHGTFD--VDTQ----TCSCHAKWSGEDCSKEVCSLECGP-------HGRC 1054
             +C   C   HGT +  +D+     T +C    +G  C K+  +  CGP       H  C
Sbjct: 786  PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA--CGPYVQFCHIHATC 843

Query: 1055 V----GESCSCAAGWSGE--FCS-----VRLCDARCAEHGQC-KNG----TCLCVSGW-- 1096
                   SC C AG+ G+   CS       L    C+ + +C K G    TC+C  GW  
Sbjct: 844  EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTG 903

Query: 1097 NGRHCT-LEGC--PRS--CAGHGQCRVDNDGRWECKCFDGW--DGPDC 1137
            NGR C+ +  C  P +  C  +  C     G+ EC+C  G+  +G DC
Sbjct: 904  NGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDC 951



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 64/225 (28%), Positives = 87/225 (38%), Gaps = 42/225 (18%)

Query: 878  CPNG----CSGKGECL-----MGHCQCQPGFGGDDC--------SKSVCPVLCSQRGEYI 920
            CP G    C+ +G CL      G C+C  GF G  C             P  CS  G+  
Sbjct: 1962 CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCD 2021

Query: 921  -----NGECQCNPGWKGKECSLRHDECEV--PDCNGHGHC-VNGKCSCVRGYKGK--FCG 970
                 +G+C C  GW G  C  +     V  P C+ H  C  N  C C   Y+G    C 
Sbjct: 2022 DGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCT 2081

Query: 971  EID-CPHPT--CSGHGFCIE-GT---CVCKKGWK--GADCGTMDKDALQCLPDCSGHGTF 1021
             +D C      C+    C + GT   C C+KG+K  G  C  +D  A      C  H T 
Sbjct: 2082 VVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATC 2141

Query: 1022 DV---DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAA 1063
             +       C C + + G+  +   C  E  P  RC+ ++  C A
Sbjct: 2142 KMTGPGKHKCECKSHYVGDGLN---CEPEQLPIDRCLQDNGQCHA 2183



 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 82/299 (27%), Positives = 116/299 (38%), Gaps = 67/299 (22%)

Query: 880  NGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV----LCSQRGEYI-----NGECQCNPGW 930
            +GC+      +   +C  GF G DC++  CP      CS  G+       NG C C  G+
Sbjct: 713  SGCARYCNATVKIPKCCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGF 770

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTC 990
            +G +C      C  P  N +G   N KC CV G        ID         G C+ GTC
Sbjct: 771  QGSQCQF----CSDP--NKYGPRCNKKCLCVHGTCNN---RID-------SDGACLTGTC 814

Query: 991  VCKKGWKGADCGTMDKDALQCLPD---CSGHGTFDVD--TQTCSCHAKWSGED--CSK-E 1042
              + G  G  C   DK    C P    C  H T +    T +C C A + G+   CS+ +
Sbjct: 815  --RDGSAGRLC---DKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMD 869

Query: 1043 VCSL----ECGPHGRCVG-----ESCSCAAGWSGEF--CS-VRLC----DARCAEHGQCK 1086
             C+      C  +  C+       +C C  GW+G    CS +  C       C ++  C 
Sbjct: 870  PCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCL 929

Query: 1087 -----NGTCLCVSGW--NGRHCT-LEGCPRS---CAGHGQCRVDNDGRWECKCFDGWDG 1134
                    C C  G+  NG  C  +  C      C     C+  + G W C C +G++G
Sbjct: 930  YVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988



 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 55/246 (22%)

Query: 878  CPNG----CSGKGECLMGH-----CQCQPGFGGDDCSKSV--------CPVLCS------ 914
            CP G    C+G+G C  G      C CQ GFGG  C            C  +C+      
Sbjct: 112  CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVC 171

Query: 915  QRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG-------KCSCVRGYK-- 965
              G   +G C+C   + G +C     EC    C  +  C          +C C+  Y+  
Sbjct: 172  NSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGD 231

Query: 966  GKFCGEID-CPHPTCSGHGFCI-----EGTCVCKKGWKGADCGTMDKDALQC-LPDCSGH 1018
            GK+C  I+ C    C  H  C        +C C++G++G     +  D  Q    +C   
Sbjct: 232  GKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTK 291

Query: 1019 GT---FDVDTQT-CSCHAKWS----GEDCS-KEVCSLE--CGPHGRCV----GES-CSCA 1062
             T   +D   Q+ C C   +     G  CS  ++C  +  C  +  C     G + C C 
Sbjct: 292  STVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQ 351

Query: 1063 AGWSGE 1068
             G+ G+
Sbjct: 352  KGYVGD 357



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 57/211 (27%), Positives = 80/211 (37%), Gaps = 47/211 (22%)

Query: 877  NCPNGCSGKGECL-----MGHCQCQPGFGGDDCSKSV-------CPVLCS------QRGE 918
            N  N C G G CL      G C+C  GF G  C           C   CS       +G 
Sbjct: 1351 NAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGP 1410

Query: 919  YINGECQCNPGWKGKEC--SLRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGK--FC 969
              +G C C+ GW+G  C  +   D C    C+   +C+        C C  G++G    C
Sbjct: 1411 LGDGSCDCDVGWRGVHCDNATTEDNCN-GTCHTSANCLTNSDGTASCKCAAGFQGNGTIC 1469

Query: 970  GEI---DCPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF 1021
              I   +  +  CS    C   T     C CK G+ G   G +  +   CL +  G    
Sbjct: 1470 TAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD--GIVCLEINPCLENHGGCDKN 1527

Query: 1022 DVDTQT------CSCHAKWSGEDCSKEVCSL 1046
               TQT      C+C   ++G+    +VC+L
Sbjct: 1528 AECTQTGPNQAACNCLPAYTGDG---KVCTL 1555



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 17/93 (18%)

Query: 1059 CSCAAGWSGEFCSVRL-------CDARCA-EHGQCK-----NGTCLCVSGWNGRHC---- 1101
            C C  G+SG  C           CD  C+  HG+C      +G+C C  GW G HC    
Sbjct: 1372 CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 1431

Query: 1102 TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
            T + C  +C     C  ++DG   CKC  G+ G
Sbjct: 1432 TEDNCNGTCHTSANCLTNSDGTASCKCAAGFQG 1464



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 51/158 (32%), Positives = 62/158 (39%), Gaps = 19/158 (12%)

Query: 989  TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLEC 1048
            +C    G K  D  TM       + DC    TF+V T + S         C K+     C
Sbjct: 45   SCALNLGVKCPDGYTMITSGSVGVRDC--RYTFEVRTYSLSLPG--CRHICRKDYLQPRC 100

Query: 1049 GPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHC------T 1102
             P GR  G  C    G +G  C+ R     CAE G   NGTC C  G+ G  C       
Sbjct: 101  CP-GRW-GPDCIECPGGAGSPCNGR---GSCAE-GMEGNGTCSCQEGFGGTACETCADDN 154

Query: 1103 LEG--CPRSC-AGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L G  C   C   HG C    DG   C+C+  + GP C
Sbjct: 155  LFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKC 192



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 59/211 (27%), Positives = 80/211 (37%), Gaps = 54/211 (25%)

Query: 960  CVRGYKGKFCGEIDCP---HPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQC 1011
            C  G+ G  C    CP      C G+G C++G      C C +G+ G  C T        
Sbjct: 1336 CCAGFFGPQCQP--CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET-------- 1385

Query: 1012 LPDCSGHGTFDVDT-QTCSC-HAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEF 1069
               C+  G + +   Q CSC H +     C++       GP G     SC C  GW G  
Sbjct: 1386 ---CT-EGKYGIHCDQACSCVHGR-----CNQ-------GPLG---DGSCDCDVGWRGVH 1426

Query: 1070 CSVRL----CDARCAEHGQC---KNGT--CLCVSGW--NGRHCT-LEGCPRS---CAGHG 1114
            C        C+  C     C    +GT  C C +G+  NG  CT +  C  S   C+   
Sbjct: 1427 CDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKA 1486

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQIC 1145
             C+    GR  C C  G+ G     L+   C
Sbjct: 1487 DCKRTTPGRRVCTCKAGYTGDGIVCLEINPC 1517



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 48/153 (31%), Positives = 62/153 (40%), Gaps = 33/153 (21%)

Query: 1014 DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVC--------SLECGPHGRC--VGESCSCAA 1063
            D SG     V+T +C    +WS     K+ C        +LE G   RC  V +   C  
Sbjct: 1897 DASGECGSCVNTPSCP---RWSKPKGVKQKCLYNLPFKRNLE-GCRERCSLVIQIPRCCK 1952

Query: 1064 GWSGEFCSVRLC----DARCAEHGQCKN-----GTCLCVSGWNGRHCTL--------EGC 1106
            G+ G  C    C    DA C   G C +     G C C +G+NG  C +        +  
Sbjct: 1953 GYFGRDCQA--CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCL 2010

Query: 1107 PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            P  C+ HGQC     G  +C C  GW GP C T
Sbjct: 2011 PCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT 2043



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 41/135 (30%), Positives = 55/135 (40%), Gaps = 21/135 (15%)

Query: 877 NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSV-------CP--VLCSQRGEYING-ECQC 926
           NC +G    G    G C+C   + G  C K +       CP    CS   E  N  EC+C
Sbjct: 165 NCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKC 224

Query: 927 NPGWK--GKECSLRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGKFCGEIDCPHPTC 979
            P ++  GK C    + C    C+ H HC         C+C  GY+G   G++  P   C
Sbjct: 225 LPNYRGDGKYCD-PINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGD--GQVCLPVDPC 281

Query: 980 S-GHGFCIEGTCVCK 993
               G C   + VCK
Sbjct: 282 QINFGNCPTKSTVCK 296



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 16/125 (12%)

Query: 1061 CAAGWSGEFCSVRLCDAR--CAEHGQCK---NGT--CLCVSGWNGRHCTL--EG-----C 1106
            C AG+ G  C     +A+  C  +G C    NGT  C C  G++G  C    EG     C
Sbjct: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 1395

Query: 1107 PRSCAG-HGQCRVDNDGRWECKCFDGWDGPDC-TTLKEQICDDSRDNDKDGLVDCEDPEC 1164
             ++C+  HG+C     G   C C  GW G  C     E  C+ +     + L + +    
Sbjct: 1396 DQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTAS 1455

Query: 1165 CQSPA 1169
            C+  A
Sbjct: 1456 CKCAA 1460



 Score = 37.9 bits (84), Expect = 0.55
 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 10/85 (11%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDG 1122
            +SG F S++   + CA +         C  G+ G  C     G    C+G+GQC     G
Sbjct: 704  YSGRFGSLK---SGCARYCNATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGG 760

Query: 1123 RWECKCFDGWDGPDCTTLKEQICDD 1147
               C C +G+ G  C     Q C D
Sbjct: 761  NGTCICEEGFQGSQC-----QFCSD 780


>AC008273-1|AAF19247.2|  291|Homo sapiens unknown protein.
          Length = 291

 Score = 87.4 bits (207), Expect = 7e-16
 Identities = 75/254 (29%), Positives = 106/254 (41%), Gaps = 39/254 (15%)

Query: 913  CSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCV---------NGKCSCVRG 963
            C+ +       C C   + G  C   +D C+   C  +  C+         N  C C+ G
Sbjct: 42   CTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPG 100

Query: 964  YKGKFC-GEID-CPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPDCSG 1017
            Y G+ C  +ID C    C     CI      TC C +G+ G+ C     D     P C  
Sbjct: 101  YTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEK-VDPCASSP-CQN 158

Query: 1018 HGTFDVDTQ--TCSCHAKWSGEDCSK--EVCSLECGPHGRC--VGES--CSCAAGWSGEF 1069
            +GT  VD    TC+C   ++G  C++  + C+L    HG C  VG S  C C  G+ G +
Sbjct: 159  NGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLY 218

Query: 1070 CSVRL--C-DARCAEHGQCK---NG-TCLCVSGWNGRHCTL--EGCPR-SCAGHGQCRVD 1119
            C      C  A C     C+   NG  C+C++ + G HC L  + C   SC     C  D
Sbjct: 219  CEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATC--D 276

Query: 1120 NDG-RWECKCFDGW 1132
            +DG    C C  G+
Sbjct: 277  SDGLNGTCICAPGF 290



 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 74/258 (28%), Positives = 99/258 (38%), Gaps = 46/258 (17%)

Query: 882  CSGKGECLMG------HCQCQPGFGG------DDCSKSVCP--VLCSQRGEYINGE---C 924
            CSGKG+C          C C+  + G      D C +  C     C    E  +G    C
Sbjct: 36   CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTC 95

Query: 925  QCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGE-ID-CPHPT 978
             C PG+ G+ C  + D C +  C     C++      C C  GY G  C E +D C    
Sbjct: 96   VCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSP 155

Query: 979  CSGHGFC-IEG---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF-DVDTQ-TCSCHA 1032
            C  +G C ++G   TC C  G+ G  C  +       L  C+ HGT   V T   C C  
Sbjct: 156  CQNNGTCYVDGVHFTCNCSPGFTGPTCAQLID--FCALSPCA-HGTCRSVGTSYKCLCDP 212

Query: 1033 KWSGEDCSKEV--C-SLECGPHGRC----VGESCSCAAGWSGEFCSV---RLCDARCAEH 1082
             + G  C +E   C S  C     C     G  C C A + G  C +      +  C   
Sbjct: 213  GYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNG 272

Query: 1083 GQCK----NGTCLCVSGW 1096
              C     NGTC+C  G+
Sbjct: 273  ATCDSDGLNGTCICAPGF 290



 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 26/152 (17%)

Query: 1014 DCSGHGTFDVD----TQTCSCHAKWSGEDCSK-EVCSLE-CGPHGRCVGES--------- 1058
            +CSG G         T +C+C  ++ G  C + + C  + C  +  C+  +         
Sbjct: 35   ECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFT 94

Query: 1059 CSCAAGWSGEFCSVRL--CDAR-CAEHGQCKNG----TCLCVSGWNGRHCT--LEGCPRS 1109
            C C  G++GE C  ++  C    C     C +     TC C  G+ G  C   ++ C  S
Sbjct: 95   CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 154

Query: 1110 -CAGHGQCRVDNDGRWECKCFDGWDGPDCTTL 1140
             C  +G C VD    + C C  G+ GP C  L
Sbjct: 155  PCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQL 185



 Score = 41.9 bits (94), Expect = 0.034
 Identities = 34/142 (23%), Positives = 54/142 (38%), Gaps = 19/142 (13%)

Query: 1046 LECGPHGRCVGE------SCSCAAGWSGEFCS-VRLCDAR-CAEHGQC---------KNG 1088
            LEC   G+C  +      SC+C   + G FC     C  + C  +  C          N 
Sbjct: 34   LECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNF 93

Query: 1089 TCLCVSGWNGRHC--TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICD 1146
            TC+C+ G+ G  C   ++ C      +G   + +   + C+C +G+ G  C    +    
Sbjct: 94   TCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCAS 153

Query: 1147 DSRDNDKDGLVDCEDPECCQSP 1168
                N+    VD     C  SP
Sbjct: 154  SPCQNNGTCYVDGVHFTCNCSP 175


>AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein
            protein.
          Length = 3574

 Score = 86.6 bits (205), Expect = 1e-15
 Identities = 70/233 (30%), Positives = 102/233 (43%), Gaps = 35/233 (15%)

Query: 870  VAEEMTHNCP-NGCSGKGECLM---GH-CQCQPGFGGDDCSKSV--C-PVLCSQRG--EY 919
            ++ ++ H C  N C   G C     G+ C C  G+ G  C   +  C P+ C   G  + 
Sbjct: 1189 ISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKD 1248

Query: 920  INGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI 972
            + GE  C+C  G+ G+ C    +EC    C   G CV+G    +C+CV+G+ G  C  E+
Sbjct: 1249 LVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEV 1308

Query: 973  -DCPHPTCSGHGFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVD 1024
             +C    C  +  C   + G  C C  G+ G  CG   K+  +CL   C    T     +
Sbjct: 1309 NECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCG---KNVDECLSQPCKNGATCKDGAN 1365

Query: 1025 TQTCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFC 1070
            +  C C A ++G  C     E  S  C     CV E    SC C  G+SG+ C
Sbjct: 1366 SFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 65/219 (29%), Positives = 92/219 (42%), Gaps = 32/219 (14%)

Query: 913  CSQRGE-YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGK 967
            C Q G  Y+   C C  G+ G +C    DEC    C  +G C +  G+  C C  GY G+
Sbjct: 1208 CQQLGRGYV---CLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1264

Query: 968  FCGEI--DCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF 1021
             C E   +C    C   G C++G     C C KG+ G  C T + +  Q  P C  +   
Sbjct: 1265 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET-EVNECQSNP-CLNNAVC 1322

Query: 1022 D--VDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVGES----CSCAAGWSGEFCSV 1072
            +  V    C C   + G  C K V  C S  C     C   +    C CAAG++G  C +
Sbjct: 1323 EDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCEL 1382

Query: 1073 RL--CDAR-CAEHGQC----KNGTCLCVSGWNGRHCTLE 1104
             +  C +  C     C     + +C C  G++G+ C  E
Sbjct: 1383 NINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421



 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            CSC   W G  C + +C L C   GRCV    C C  GW+G  C   +C + C   G+C 
Sbjct: 3491 CSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCV 3550

Query: 1086 KNGTCLCVSGWNGRHCT 1102
            +   C C+S W G +C+
Sbjct: 3551 RPNRCHCLSSWTGHNCS 3567



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 67/229 (29%), Positives = 89/229 (38%), Gaps = 34/229 (14%)

Query: 941  ECEVPDCNGHGHCVN-GK---CSCVRGYKGKFCG-EID-CPHPTCSGHGFCI----EGTC 990
            EC    C+  G C   G+   C C  GY G  C  +ID C    C  +G C     E  C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255

Query: 991  VCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTCSCHAKWSGEDCSKEVCSLE 1047
             C  G+ G  C   +++  +C    C   G     V    C+C   + G  C  EV   +
Sbjct: 1256 ECPSGYTGQRC---EENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1312

Query: 1048 CGP-------HGRCVGESCSCAAGWSGEFC--SVRLCDAR-CAEHGQCKNGT----CLCV 1093
              P         +  G  C C  G+ G  C  +V  C ++ C     CK+G     CLC 
Sbjct: 1313 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1372

Query: 1094 SGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            +G+ G HC L   E     C     C VD    + CKC  G+ G  C T
Sbjct: 1373 AGFTGSHCELNINECQSNPCRNQATC-VDELNSYSCKCQPGFSGKRCET 1420



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 6/113 (5%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            C  +  W+     + VC   C   G C    +CSC  GW G  C   +C   C   G+C 
Sbjct: 3459 CLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCV 3518

Query: 1086 KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                C C  GW G  C    C   C   G+C   N     C C   W G +C+
Sbjct: 3519 APYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPN----RCHCLSSWTGHNCS 3567



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%)

Query: 942  CEVPDCNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEG-TCVCKKGWKGA 999
            C  P C   G C     CSC  G+ G+ C E  C  P C   G C+    C C  GW G+
Sbjct: 3475 CRFP-CQNGGICQRPNACSCPEGWMGRLCEEPICILP-CLNGGRCVAPYQCDCPPGWTGS 3532

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
             C T       C   C   G   V    C C + W+G +CS++
Sbjct: 3533 RCHT-----AVCQSPCLNGGKC-VRPNRCHCLSSWTGHNCSRK 3569



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C   C   G C   + C C  G+ G  C + +C + C   G  +   +C C PGW G  C
Sbjct: 3475 CRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRC 3534

Query: 936  SLRHDECEVPDCNGHGHCVN-GKCSCVRGYKGKFC 969
                  C+ P  NG G CV   +C C+  + G  C
Sbjct: 3535 HTA--VCQSPCLNG-GKCVRPNRCHCLSSWTGHNC 3566



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            C   C   G C+  + C C PG+ G  C  +VC   C   G+ +    C C   W G  C
Sbjct: 3507 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3566

Query: 936  S 936
            S
Sbjct: 3567 S 3567



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            W+       +C   C   G C+    C C  GW GR C    C   C   G+C       
Sbjct: 3465 WTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAP---- 3520

Query: 1124 WECKCFDGWDGPDCTT 1139
            ++C C  GW G  C T
Sbjct: 3521 YQCDCPPGWTGSRCHT 3536



 Score = 35.5 bits (78), Expect = 2.9
 Identities = 67/261 (25%), Positives = 92/261 (35%), Gaps = 43/261 (16%)

Query: 868  ALVAEEMTHNCPNGCSGKGECL--MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            + + ++M H C   C    +C   MG C+C    G  +C   +C       G+ +  EC 
Sbjct: 268  SFIQDDMVH-CSYLCDEGKDCCDRMGSCKCGTHTGHFEC---ICEK--GYYGKGLQYECT 321

Query: 926  CNPG--WKGKECSLRHDEC-EVPDCNGH---GHCVNGKCSCVRGYK--GKFCGEIDCPHP 977
              P   +K +        C   PD N     G      C C  GY+  G+ C  + CP  
Sbjct: 322  ACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPAL 381

Query: 978  TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGE 1037
                +G+ I+ TC        A CG      ++C P   G          C  +  WSG 
Sbjct: 382  KPPENGYFIQNTC---NNHFNAACG------VRCHP---GFDLVGSSIILCLPNGLWSGL 429

Query: 1038 D--CSKEVC-SLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVS 1094
            +  C    C  L    HG     SCS         C V  CD      G  K  TC   S
Sbjct: 430  ESYCRVRTCPHLRQPKHGHI---SCSTREMLYKTTCLV-ACDEGYRLEGSDKL-TCQGNS 484

Query: 1095 GWNG-------RHCTLEGCPR 1108
             W+G       RHC+    P+
Sbjct: 485  QWDGPEPRCVERHCSTFQMPK 505


>AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand factor
            type A, EGF and pentraxin domain containing 1 protein.
          Length = 3548

 Score = 86.6 bits (205), Expect = 1e-15
 Identities = 70/233 (30%), Positives = 102/233 (43%), Gaps = 35/233 (15%)

Query: 870  VAEEMTHNCP-NGCSGKGECLM---GH-CQCQPGFGGDDCSKSV--C-PVLCSQRG--EY 919
            ++ ++ H C  N C   G C     G+ C C  G+ G  C   +  C P+ C   G  + 
Sbjct: 1166 ISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKD 1225

Query: 920  INGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI 972
            + GE  C+C  G+ G+ C    +EC    C   G CV+G    +C+CV+G+ G  C  E+
Sbjct: 1226 LVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEV 1285

Query: 973  -DCPHPTCSGHGFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVD 1024
             +C    C  +  C   + G  C C  G+ G  CG   K+  +CL   C    T     +
Sbjct: 1286 NECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCG---KNVDECLSQPCKNGATCKDGAN 1342

Query: 1025 TQTCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFC 1070
            +  C C A ++G  C     E  S  C     CV E    SC C  G+SG+ C
Sbjct: 1343 SFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1395



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 65/219 (29%), Positives = 92/219 (42%), Gaps = 32/219 (14%)

Query: 913  CSQRGE-YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGK 967
            C Q G  Y+   C C  G+ G +C    DEC    C  +G C +  G+  C C  GY G+
Sbjct: 1185 CQQLGRGYV---CLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1241

Query: 968  FCGEI--DCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF 1021
             C E   +C    C   G C++G     C C KG+ G  C T + +  Q  P C  +   
Sbjct: 1242 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET-EVNECQSNP-CLNNAVC 1299

Query: 1022 D--VDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVGES----CSCAAGWSGEFCSV 1072
            +  V    C C   + G  C K V  C S  C     C   +    C CAAG++G  C +
Sbjct: 1300 EDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCEL 1359

Query: 1073 RL--CDAR-CAEHGQC----KNGTCLCVSGWNGRHCTLE 1104
             +  C +  C     C     + +C C  G++G+ C  E
Sbjct: 1360 NINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1398



 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            CSC   W G  C + +C L C   GRCV    C C  GW+G  C   +C + C   G+C 
Sbjct: 3465 CSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCV 3524

Query: 1086 KNGTCLCVSGWNGRHCT 1102
            +   C C+S W G +C+
Sbjct: 3525 RPNRCHCLSSWTGHNCS 3541



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 67/229 (29%), Positives = 89/229 (38%), Gaps = 34/229 (14%)

Query: 941  ECEVPDCNGHGHCVN-GK---CSCVRGYKGKFCG-EID-CPHPTCSGHGFCI----EGTC 990
            EC    C+  G C   G+   C C  GY G  C  +ID C    C  +G C     E  C
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1232

Query: 991  VCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTCSCHAKWSGEDCSKEVCSLE 1047
             C  G+ G  C   +++  +C    C   G     V    C+C   + G  C  EV   +
Sbjct: 1233 ECPSGYTGQRC---EENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1289

Query: 1048 CGP-------HGRCVGESCSCAAGWSGEFC--SVRLCDAR-CAEHGQCKNGT----CLCV 1093
              P         +  G  C C  G+ G  C  +V  C ++ C     CK+G     CLC 
Sbjct: 1290 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1349

Query: 1094 SGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            +G+ G HC L   E     C     C VD    + CKC  G+ G  C T
Sbjct: 1350 AGFTGSHCELNINECQSNPCRNQATC-VDELNSYSCKCQPGFSGKRCET 1397



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 6/113 (5%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            C  +  W+     + VC   C   G C    +CSC  GW G  C   +C   C   G+C 
Sbjct: 3433 CLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCV 3492

Query: 1086 KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                C C  GW G  C    C   C   G+C   N     C C   W G +C+
Sbjct: 3493 APYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPN----RCHCLSSWTGHNCS 3541



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%)

Query: 942  CEVPDCNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEG-TCVCKKGWKGA 999
            C  P C   G C     CSC  G+ G+ C E  C  P C   G C+    C C  GW G+
Sbjct: 3449 CRFP-CQNGGICQRPNACSCPEGWMGRLCEEPICILP-CLNGGRCVAPYQCDCPPGWTGS 3506

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
             C T       C   C   G   V    C C + W+G +CS++
Sbjct: 3507 RCHT-----AVCQSPCLNGGKC-VRPNRCHCLSSWTGHNCSRK 3543



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C   C   G C   + C C  G+ G  C + +C + C   G  +   +C C PGW G  C
Sbjct: 3449 CRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRC 3508

Query: 936  SLRHDECEVPDCNGHGHCVN-GKCSCVRGYKGKFC 969
                  C+ P  NG G CV   +C C+  + G  C
Sbjct: 3509 HTA--VCQSPCLNG-GKCVRPNRCHCLSSWTGHNC 3540



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            C   C   G C+  + C C PG+ G  C  +VC   C   G+ +    C C   W G  C
Sbjct: 3481 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3540

Query: 936  S 936
            S
Sbjct: 3541 S 3541



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            W+       +C   C   G C+    C C  GW GR C    C   C   G+C       
Sbjct: 3439 WTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAP---- 3494

Query: 1124 WECKCFDGWDGPDCTT 1139
            ++C C  GW G  C T
Sbjct: 3495 YQCDCPPGWTGSRCHT 3510



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 67/261 (25%), Positives = 92/261 (35%), Gaps = 43/261 (16%)

Query: 868  ALVAEEMTHNCPNGCSGKGECL--MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            + + ++M H C   C    +C   MG C+C    G  +C   +C       G+ +  EC 
Sbjct: 245  SFIQDDMVH-CSYLCDEGKDCCDRMGSCKCGTHTGHFEC---ICEK--GYYGKGLQYECT 298

Query: 926  CNPG--WKGKECSLRHDEC-EVPDCNGH---GHCVNGKCSCVRGYK--GKFCGEIDCPHP 977
              P   +K +        C   PD N     G      C C  GY+  G+ C  + CP  
Sbjct: 299  ACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPAL 358

Query: 978  TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGE 1037
                +G+ I+ TC        A CG      ++C P   G          C  +  WSG 
Sbjct: 359  KPPENGYFIQNTC---NNHFNAACG------VRCHP---GFDLVGSSIILCLPNGLWSGS 406

Query: 1038 D--CSKEVC-SLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVS 1094
            +  C    C  L    HG     SCS         C V  CD      G  K  TC   S
Sbjct: 407  ESYCRVRTCPHLRQPKHGHI---SCSTREMLYKTTCLV-ACDEGYRLEGSDKL-TCQGNS 461

Query: 1095 GWNG-------RHCTLEGCPR 1108
             W+G       RHC+    P+
Sbjct: 462  QWDGPEPRCVERHCSTFQMPK 482


>AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand factor
            type A, EGF and pentraxin domain containing 1 protein.
          Length = 3548

 Score = 86.6 bits (205), Expect = 1e-15
 Identities = 70/233 (30%), Positives = 102/233 (43%), Gaps = 35/233 (15%)

Query: 870  VAEEMTHNCP-NGCSGKGECLM---GH-CQCQPGFGGDDCSKSV--C-PVLCSQRG--EY 919
            ++ ++ H C  N C   G C     G+ C C  G+ G  C   +  C P+ C   G  + 
Sbjct: 1166 ISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKD 1225

Query: 920  INGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI 972
            + GE  C+C  G+ G+ C    +EC    C   G CV+G    +C+CV+G+ G  C  E+
Sbjct: 1226 LVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEV 1285

Query: 973  -DCPHPTCSGHGFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVD 1024
             +C    C  +  C   + G  C C  G+ G  CG   K+  +CL   C    T     +
Sbjct: 1286 NECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCG---KNVDECLSQPCKNGATCKDGAN 1342

Query: 1025 TQTCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFC 1070
            +  C C A ++G  C     E  S  C     CV E    SC C  G+SG+ C
Sbjct: 1343 SFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1395



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 65/219 (29%), Positives = 92/219 (42%), Gaps = 32/219 (14%)

Query: 913  CSQRGE-YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGK 967
            C Q G  Y+   C C  G+ G +C    DEC    C  +G C +  G+  C C  GY G+
Sbjct: 1185 CQQLGRGYV---CLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1241

Query: 968  FCGEI--DCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF 1021
             C E   +C    C   G C++G     C C KG+ G  C T + +  Q  P C  +   
Sbjct: 1242 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET-EVNECQSNP-CLNNAVC 1299

Query: 1022 D--VDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVGES----CSCAAGWSGEFCSV 1072
            +  V    C C   + G  C K V  C S  C     C   +    C CAAG++G  C +
Sbjct: 1300 EDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCEL 1359

Query: 1073 RL--CDAR-CAEHGQC----KNGTCLCVSGWNGRHCTLE 1104
             +  C +  C     C     + +C C  G++G+ C  E
Sbjct: 1360 NINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1398



 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            CSC   W G  C + +C L C   GRCV    C C  GW+G  C   +C + C   G+C 
Sbjct: 3465 CSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCV 3524

Query: 1086 KNGTCLCVSGWNGRHCT 1102
            +   C C+S W G +C+
Sbjct: 3525 RPNRCHCLSSWTGHNCS 3541



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 67/229 (29%), Positives = 89/229 (38%), Gaps = 34/229 (14%)

Query: 941  ECEVPDCNGHGHCVN-GK---CSCVRGYKGKFCG-EID-CPHPTCSGHGFCI----EGTC 990
            EC    C+  G C   G+   C C  GY G  C  +ID C    C  +G C     E  C
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1232

Query: 991  VCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTCSCHAKWSGEDCSKEVCSLE 1047
             C  G+ G  C   +++  +C    C   G     V    C+C   + G  C  EV   +
Sbjct: 1233 ECPSGYTGQRC---EENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1289

Query: 1048 CGP-------HGRCVGESCSCAAGWSGEFC--SVRLCDAR-CAEHGQCKNGT----CLCV 1093
              P         +  G  C C  G+ G  C  +V  C ++ C     CK+G     CLC 
Sbjct: 1290 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1349

Query: 1094 SGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            +G+ G HC L   E     C     C VD    + CKC  G+ G  C T
Sbjct: 1350 AGFTGSHCELNINECQSNPCRNQATC-VDELNSYSCKCQPGFSGKRCET 1397



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 6/113 (5%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            C  +  W+     + VC   C   G C    +CSC  GW G  C   +C   C   G+C 
Sbjct: 3433 CLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCV 3492

Query: 1086 KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                C C  GW G  C    C   C   G+C   N     C C   W G +C+
Sbjct: 3493 APYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPN----RCHCLSSWTGHNCS 3541



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%)

Query: 942  CEVPDCNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEG-TCVCKKGWKGA 999
            C  P C   G C     CSC  G+ G+ C E  C  P C   G C+    C C  GW G+
Sbjct: 3449 CRFP-CQNGGICQRPNACSCPEGWMGRLCEEPICILP-CLNGGRCVAPYQCDCPPGWTGS 3506

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
             C T       C   C   G   V    C C + W+G +CS++
Sbjct: 3507 RCHT-----AVCQSPCLNGGKC-VRPNRCHCLSSWTGHNCSRK 3543



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C   C   G C   + C C  G+ G  C + +C + C   G  +   +C C PGW G  C
Sbjct: 3449 CRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRC 3508

Query: 936  SLRHDECEVPDCNGHGHCVN-GKCSCVRGYKGKFC 969
                  C+ P  NG G CV   +C C+  + G  C
Sbjct: 3509 HTA--VCQSPCLNG-GKCVRPNRCHCLSSWTGHNC 3540



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            C   C   G C+  + C C PG+ G  C  +VC   C   G+ +    C C   W G  C
Sbjct: 3481 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3540

Query: 936  S 936
            S
Sbjct: 3541 S 3541



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            W+       +C   C   G C+    C C  GW GR C    C   C   G+C       
Sbjct: 3439 WTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAP---- 3494

Query: 1124 WECKCFDGWDGPDCTT 1139
            ++C C  GW G  C T
Sbjct: 3495 YQCDCPPGWTGSRCHT 3510



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 67/261 (25%), Positives = 92/261 (35%), Gaps = 43/261 (16%)

Query: 868  ALVAEEMTHNCPNGCSGKGECL--MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            + + ++M H C   C    +C   MG C+C    G  +C   +C       G+ +  EC 
Sbjct: 245  SFIQDDMVH-CSYLCDEGKDCCDRMGSCKCGTHTGHFEC---ICEK--GYYGKGLQYECT 298

Query: 926  CNPG--WKGKECSLRHDEC-EVPDCNGH---GHCVNGKCSCVRGYK--GKFCGEIDCPHP 977
              P   +K +        C   PD N     G      C C  GY+  G+ C  + CP  
Sbjct: 299  ACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPAL 358

Query: 978  TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGE 1037
                +G+ I+ TC        A CG      ++C P   G          C  +  WSG 
Sbjct: 359  KPPENGYFIQNTC---NNHFNAACG------VRCHP---GFDLVGSSIILCLPNGLWSGS 406

Query: 1038 D--CSKEVC-SLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVS 1094
            +  C    C  L    HG     SCS         C V  CD      G  K  TC   S
Sbjct: 407  ESYCRVRTCPHLRQPKHGHI---SCSTREMLYKTTCLV-ACDEGYRLEGSDKL-TCQGNS 461

Query: 1095 GWNG-------RHCTLEGCPR 1108
             W+G       RHC+    P+
Sbjct: 462  QWDGPEPRCVERHCSTFQMPK 482


>AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand factor
            type A, EGF and pentraxin domain containing 1 protein.
          Length = 3548

 Score = 86.6 bits (205), Expect = 1e-15
 Identities = 70/233 (30%), Positives = 102/233 (43%), Gaps = 35/233 (15%)

Query: 870  VAEEMTHNCP-NGCSGKGECLM---GH-CQCQPGFGGDDCSKSV--C-PVLCSQRG--EY 919
            ++ ++ H C  N C   G C     G+ C C  G+ G  C   +  C P+ C   G  + 
Sbjct: 1166 ISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKD 1225

Query: 920  INGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI 972
            + GE  C+C  G+ G+ C    +EC    C   G CV+G    +C+CV+G+ G  C  E+
Sbjct: 1226 LVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEV 1285

Query: 973  -DCPHPTCSGHGFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVD 1024
             +C    C  +  C   + G  C C  G+ G  CG   K+  +CL   C    T     +
Sbjct: 1286 NECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCG---KNVDECLSQPCKNGATCKDGAN 1342

Query: 1025 TQTCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFC 1070
            +  C C A ++G  C     E  S  C     CV E    SC C  G+SG+ C
Sbjct: 1343 SFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1395



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 65/219 (29%), Positives = 92/219 (42%), Gaps = 32/219 (14%)

Query: 913  CSQRGE-YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGK 967
            C Q G  Y+   C C  G+ G +C    DEC    C  +G C +  G+  C C  GY G+
Sbjct: 1185 CQQLGRGYV---CLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1241

Query: 968  FCGEI--DCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF 1021
             C E   +C    C   G C++G     C C KG+ G  C T + +  Q  P C  +   
Sbjct: 1242 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET-EVNECQSNP-CLNNAVC 1299

Query: 1022 D--VDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVGES----CSCAAGWSGEFCSV 1072
            +  V    C C   + G  C K V  C S  C     C   +    C CAAG++G  C +
Sbjct: 1300 EDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCEL 1359

Query: 1073 RL--CDAR-CAEHGQC----KNGTCLCVSGWNGRHCTLE 1104
             +  C +  C     C     + +C C  G++G+ C  E
Sbjct: 1360 NINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1398



 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            CSC   W G  C + +C L C   GRCV    C C  GW+G  C   +C + C   G+C 
Sbjct: 3465 CSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCV 3524

Query: 1086 KNGTCLCVSGWNGRHCT 1102
            +   C C+S W G +C+
Sbjct: 3525 RPNRCHCLSSWTGHNCS 3541



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 67/229 (29%), Positives = 89/229 (38%), Gaps = 34/229 (14%)

Query: 941  ECEVPDCNGHGHCVN-GK---CSCVRGYKGKFCG-EID-CPHPTCSGHGFCI----EGTC 990
            EC    C+  G C   G+   C C  GY G  C  +ID C    C  +G C     E  C
Sbjct: 1173 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1232

Query: 991  VCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTCSCHAKWSGEDCSKEVCSLE 1047
             C  G+ G  C   +++  +C    C   G     V    C+C   + G  C  EV   +
Sbjct: 1233 ECPSGYTGQRC---EENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1289

Query: 1048 CGP-------HGRCVGESCSCAAGWSGEFC--SVRLCDAR-CAEHGQCKNGT----CLCV 1093
              P         +  G  C C  G+ G  C  +V  C ++ C     CK+G     CLC 
Sbjct: 1290 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1349

Query: 1094 SGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            +G+ G HC L   E     C     C VD    + CKC  G+ G  C T
Sbjct: 1350 AGFTGSHCELNINECQSNPCRNQATC-VDELNSYSCKCQPGFSGKRCET 1397



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 6/113 (5%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            C  +  W+     + VC   C   G C    +CSC  GW G  C   +C   C   G+C 
Sbjct: 3433 CLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCV 3492

Query: 1086 KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                C C  GW G  C    C   C   G+C   N     C C   W G +C+
Sbjct: 3493 APYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPN----RCHCLSSWTGHNCS 3541



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%)

Query: 942  CEVPDCNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEG-TCVCKKGWKGA 999
            C  P C   G C     CSC  G+ G+ C E  C  P C   G C+    C C  GW G+
Sbjct: 3449 CRFP-CQNGGICQRPNACSCPEGWMGRLCEEPICILP-CLNGGRCVAPYQCDCPPGWTGS 3506

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
             C T       C   C   G   V    C C + W+G +CS++
Sbjct: 3507 RCHT-----AVCQSPCLNGGKC-VRPNRCHCLSSWTGHNCSRK 3543



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C   C   G C   + C C  G+ G  C + +C + C   G  +   +C C PGW G  C
Sbjct: 3449 CRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRC 3508

Query: 936  SLRHDECEVPDCNGHGHCVN-GKCSCVRGYKGKFC 969
                  C+ P  NG G CV   +C C+  + G  C
Sbjct: 3509 HTA--VCQSPCLNG-GKCVRPNRCHCLSSWTGHNC 3540



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            C   C   G C+  + C C PG+ G  C  +VC   C   G+ +    C C   W G  C
Sbjct: 3481 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3540

Query: 936  S 936
            S
Sbjct: 3541 S 3541



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            W+       +C   C   G C+    C C  GW GR C    C   C   G+C       
Sbjct: 3439 WTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAP---- 3494

Query: 1124 WECKCFDGWDGPDCTT 1139
            ++C C  GW G  C T
Sbjct: 3495 YQCDCPPGWTGSRCHT 3510



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 67/261 (25%), Positives = 92/261 (35%), Gaps = 43/261 (16%)

Query: 868  ALVAEEMTHNCPNGCSGKGECL--MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            + + ++M H C   C    +C   MG C+C    G  +C   +C       G+ +  EC 
Sbjct: 245  SFIQDDMVH-CSYLCDEGKDCCDRMGSCKCGTHTGHFEC---ICEK--GYYGKGLQYECT 298

Query: 926  CNPG--WKGKECSLRHDEC-EVPDCNGH---GHCVNGKCSCVRGYK--GKFCGEIDCPHP 977
              P   +K +        C   PD N     G      C C  GY+  G+ C  + CP  
Sbjct: 299  ACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPAL 358

Query: 978  TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGE 1037
                +G+ I+ TC        A CG      ++C P   G          C  +  WSG 
Sbjct: 359  KPPENGYFIQNTC---NNHFNAACG------VRCHP---GFDLVGSSIILCLPNGLWSGS 406

Query: 1038 D--CSKEVC-SLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVS 1094
            +  C    C  L    HG     SCS         C V  CD      G  K  TC   S
Sbjct: 407  ESYCRVRTCPHLRQPKHGHI---SCSTREMLYKTTCLV-ACDEGYRLEGSDKL-TCQGNS 461

Query: 1095 GWNG-------RHCTLEGCPR 1108
             W+G       RHC+    P+
Sbjct: 462  QWDGPEPRCVERHCSTFQMPK 482


>AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens cDNA
            FLJ14964 fis, clone PLACE4000581, moderately similar to
            FIBROPELLIN I PRECURSOR. ).
          Length = 1316

 Score = 86.6 bits (205), Expect = 1e-15
 Identities = 70/233 (30%), Positives = 102/233 (43%), Gaps = 35/233 (15%)

Query: 870  VAEEMTHNCP-NGCSGKGECLM---GH-CQCQPGFGGDDCSKSV--C-PVLCSQRG--EY 919
            ++ ++ H C  N C   G C     G+ C C  G+ G  C   +  C P+ C   G  + 
Sbjct: 956  ISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKD 1015

Query: 920  INGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI 972
            + GE  C+C  G+ G+ C    +EC    C   G CV+G    +C+CV+G+ G  C  E+
Sbjct: 1016 LVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEV 1075

Query: 973  -DCPHPTCSGHGFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVD 1024
             +C    C  +  C   + G  C C  G+ G  CG   K+  +CL   C    T     +
Sbjct: 1076 NECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCG---KNVDECLSQPCKNGATCKDGAN 1132

Query: 1025 TQTCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFC 1070
            +  C C A ++G  C     E  S  C     CV E    SC C  G+SG+ C
Sbjct: 1133 SFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1185



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 65/219 (29%), Positives = 92/219 (42%), Gaps = 32/219 (14%)

Query: 913  CSQRGE-YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGK 967
            C Q G  Y+   C C  G+ G +C    DEC    C  +G C +  G+  C C  GY G+
Sbjct: 975  CQQLGRGYV---CLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1031

Query: 968  FCGEI--DCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF 1021
             C E   +C    C   G C++G     C C KG+ G  C T + +  Q  P C  +   
Sbjct: 1032 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET-EVNECQSNP-CLNNAVC 1089

Query: 1022 D--VDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVGES----CSCAAGWSGEFCSV 1072
            +  V    C C   + G  C K V  C S  C     C   +    C CAAG++G  C +
Sbjct: 1090 EDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCEL 1149

Query: 1073 RL--CDAR-CAEHGQC----KNGTCLCVSGWNGRHCTLE 1104
             +  C +  C     C     + +C C  G++G+ C  E
Sbjct: 1150 NINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1188



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 67/229 (29%), Positives = 89/229 (38%), Gaps = 34/229 (14%)

Query: 941  ECEVPDCNGHGHCVN-GK---CSCVRGYKGKFCG-EID-CPHPTCSGHGFCI----EGTC 990
            EC    C+  G C   G+   C C  GY G  C  +ID C    C  +G C     E  C
Sbjct: 963  ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1022

Query: 991  VCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTCSCHAKWSGEDCSKEVCSLE 1047
             C  G+ G  C   +++  +C    C   G     V    C+C   + G  C  EV   +
Sbjct: 1023 ECPSGYTGQRC---EENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1079

Query: 1048 CGP-------HGRCVGESCSCAAGWSGEFC--SVRLCDAR-CAEHGQCKNGT----CLCV 1093
              P         +  G  C C  G+ G  C  +V  C ++ C     CK+G     CLC 
Sbjct: 1080 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1139

Query: 1094 SGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            +G+ G HC L   E     C     C VD    + CKC  G+ G  C T
Sbjct: 1140 AGFTGSHCELNINECQSNPCRNQATC-VDELNSYSCKCQPGFSGKRCET 1187



 Score = 35.5 bits (78), Expect = 2.9
 Identities = 67/261 (25%), Positives = 92/261 (35%), Gaps = 43/261 (16%)

Query: 868  ALVAEEMTHNCPNGCSGKGECL--MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            + + ++M H C   C    +C   MG C+C    G  +C   +C       G+ +  EC 
Sbjct: 35   SFIQDDMVH-CSYLCDEGKDCCDRMGSCKCGTHTGHFEC---ICEK--GYYGKGLQYECT 88

Query: 926  CNPG--WKGKECSLRHDEC-EVPDCNGH---GHCVNGKCSCVRGYK--GKFCGEIDCPHP 977
              P   +K +        C   PD N     G      C C  GY+  G+ C  + CP  
Sbjct: 89   ACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPAL 148

Query: 978  TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGE 1037
                +G+ I+ TC        A CG      ++C P   G          C  +  WSG 
Sbjct: 149  KPPENGYFIQNTC---NNHFNAACG------VRCHP---GFDLVGSSIILCLPNGLWSGL 196

Query: 1038 D--CSKEVC-SLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVS 1094
            +  C    C  L    HG     SCS         C V  CD      G  K  TC   S
Sbjct: 197  ESYCRVRTCPHLRQPKHGHI---SCSTREMLYKTTCLV-ACDEGYRLEGSDKL-TCQGNS 251

Query: 1095 GWNG-------RHCTLEGCPR 1108
             W+G       RHC+    P+
Sbjct: 252  QWDGPEPRCVERHCSTFQMPK 272


>AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.
          Length = 3574

 Score = 86.6 bits (205), Expect = 1e-15
 Identities = 70/233 (30%), Positives = 102/233 (43%), Gaps = 35/233 (15%)

Query: 870  VAEEMTHNCP-NGCSGKGECLM---GH-CQCQPGFGGDDCSKSV--C-PVLCSQRG--EY 919
            ++ ++ H C  N C   G C     G+ C C  G+ G  C   +  C P+ C   G  + 
Sbjct: 1189 ISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKD 1248

Query: 920  INGE--CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEI 972
            + GE  C+C  G+ G+ C    +EC    C   G CV+G    +C+CV+G+ G  C  E+
Sbjct: 1249 LVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEV 1308

Query: 973  -DCPHPTCSGHGFC---IEG-TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVD 1024
             +C    C  +  C   + G  C C  G+ G  CG   K+  +CL   C    T     +
Sbjct: 1309 NECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCG---KNVDECLSQPCKNGATCKDGAN 1365

Query: 1025 TQTCSCHAKWSGEDCS---KEVCSLECGPHGRCVGE----SCSCAAGWSGEFC 1070
            +  C C A ++G  C     E  S  C     CV E    SC C  G+SG+ C
Sbjct: 1366 SFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418



 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 65/219 (29%), Positives = 92/219 (42%), Gaps = 32/219 (14%)

Query: 913  CSQRGE-YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GK--CSCVRGYKGK 967
            C Q G  Y+   C C  G+ G +C    DEC    C  +G C +  G+  C C  GY G+
Sbjct: 1208 CQQLGRGYV---CLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQ 1264

Query: 968  FCGEI--DCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF 1021
             C E   +C    C   G C++G     C C KG+ G  C T + +  Q  P C  +   
Sbjct: 1265 RCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET-EVNECQSNP-CLNNAVC 1322

Query: 1022 D--VDTQTCSCHAKWSGEDCSKEV--C-SLECGPHGRCVGES----CSCAAGWSGEFCSV 1072
            +  V    C C   + G  C K V  C S  C     C   +    C CAAG++G  C +
Sbjct: 1323 EDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCEL 1382

Query: 1073 RL--CDAR-CAEHGQC----KNGTCLCVSGWNGRHCTLE 1104
             +  C +  C     C     + +C C  G++G+ C  E
Sbjct: 1383 NINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421



 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            CSC   W G  C + +C L C   GRCV    C C  GW+G  C   +C + C   G+C 
Sbjct: 3491 CSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCV 3550

Query: 1086 KNGTCLCVSGWNGRHCT 1102
            +   C C+S W G +C+
Sbjct: 3551 RPNRCHCLSSWTGHNCS 3567



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 67/229 (29%), Positives = 89/229 (38%), Gaps = 34/229 (14%)

Query: 941  ECEVPDCNGHGHCVN-GK---CSCVRGYKGKFCG-EID-CPHPTCSGHGFCI----EGTC 990
            EC    C+  G C   G+   C C  GY G  C  +ID C    C  +G C     E  C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255

Query: 991  VCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTCSCHAKWSGEDCSKEVCSLE 1047
             C  G+ G  C   +++  +C    C   G     V    C+C   + G  C  EV   +
Sbjct: 1256 ECPSGYTGQRC---EENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQ 1312

Query: 1048 CGP-------HGRCVGESCSCAAGWSGEFC--SVRLCDAR-CAEHGQCKNGT----CLCV 1093
              P         +  G  C C  G+ G  C  +V  C ++ C     CK+G     CLC 
Sbjct: 1313 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCA 1372

Query: 1094 SGWNGRHCTL---EGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            +G+ G HC L   E     C     C VD    + CKC  G+ G  C T
Sbjct: 1373 AGFTGSHCELNINECQSNPCRNQATC-VDELNSYSCKCQPGFSGKRCET 1420



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 6/113 (5%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            C  +  W+     + VC   C   G C    +CSC  GW G  C   +C   C   G+C 
Sbjct: 3459 CLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCV 3518

Query: 1086 KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                C C  GW G  C    C   C   G+C   N     C C   W G +C+
Sbjct: 3519 APYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPN----RCHCLSSWTGHNCS 3567



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%)

Query: 942  CEVPDCNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEG-TCVCKKGWKGA 999
            C  P C   G C     CSC  G+ G+ C E  C  P C   G C+    C C  GW G+
Sbjct: 3475 CRFP-CQNGGICQRPNACSCPEGWMGRLCEEPICILP-CLNGGRCVAPYQCDCPPGWTGS 3532

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
             C T       C   C   G   V    C C + W+G +CS++
Sbjct: 3533 RCHT-----AVCQSPCLNGGKC-VRPNRCHCLSSWTGHNCSRK 3569



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C   C   G C   + C C  G+ G  C + +C + C   G  +   +C C PGW G  C
Sbjct: 3475 CRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRC 3534

Query: 936  SLRHDECEVPDCNGHGHCVN-GKCSCVRGYKGKFC 969
                  C+ P  NG G CV   +C C+  + G  C
Sbjct: 3535 HTA--VCQSPCLNG-GKCVRPNRCHCLSSWTGHNC 3566



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            C   C   G C+  + C C PG+ G  C  +VC   C   G+ +    C C   W G  C
Sbjct: 3507 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 3566

Query: 936  S 936
            S
Sbjct: 3567 S 3567



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            W+       +C   C   G C+    C C  GW GR C    C   C   G+C       
Sbjct: 3465 WTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAP---- 3520

Query: 1124 WECKCFDGWDGPDCTT 1139
            ++C C  GW G  C T
Sbjct: 3521 YQCDCPPGWTGSRCHT 3536



 Score = 35.5 bits (78), Expect = 2.9
 Identities = 67/261 (25%), Positives = 92/261 (35%), Gaps = 43/261 (16%)

Query: 868  ALVAEEMTHNCPNGCSGKGECL--MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQ 925
            + + ++M H C   C    +C   MG C+C    G  +C   +C       G+ +  EC 
Sbjct: 268  SFIQDDMVH-CSYLCDEGKDCCDRMGSCKCGTHTGHFEC---ICEK--GYYGKGLQYECT 321

Query: 926  CNPG--WKGKECSLRHDEC-EVPDCNGH---GHCVNGKCSCVRGYK--GKFCGEIDCPHP 977
              P   +K +        C   PD N     G      C C  GY+  G+ C  + CP  
Sbjct: 322  ACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPAL 381

Query: 978  TCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGE 1037
                +G+ I+ TC        A CG      ++C P   G          C  +  WSG 
Sbjct: 382  KPPENGYFIQNTC---NNHFNAACG------VRCHP---GFDLVGSSIILCLPNGLWSGL 429

Query: 1038 D--CSKEVC-SLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVS 1094
            +  C    C  L    HG     SCS         C V  CD      G  K  TC   S
Sbjct: 430  ESYCRVRTCPHLRQPKHGHI---SCSTREMLYKTTCLV-ACDEGYRLEGSDKL-TCQGNS 484

Query: 1095 GWNG-------RHCTLEGCPR 1108
             W+G       RHC+    P+
Sbjct: 485  QWDGPEPRCVERHCSTFQMPK 505


>AK098809-1|BAC05419.1|  320|Homo sapiens protein ( Homo sapiens cDNA
            FLJ25943 fis, clone JTH10559. ).
          Length = 320

 Score = 83.0 bits (196), Expect = 1e-14
 Identities = 73/240 (30%), Positives = 97/240 (40%), Gaps = 49/240 (20%)

Query: 945  PDCNGHGHCVNGKCSC---VRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGAD 1000
            P C+    C N   SC     G  G FC      HP  +G  F   +G+C C  GW G  
Sbjct: 4    PQCDKPCSCGNNS-SCDPKSGGTSGFFCPST---HPCQNGGVFQTPQGSCSCPPGWMGTI 59

Query: 1001 CGTMDKDALQ---CLPDCSGH--GTFDVDTQTCSCHAKWSGEDCSKEV--------CS-- 1045
            C     +      C  +C  H  G  D  T  C C   ++G+ C +E         C+  
Sbjct: 60   CSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAET 119

Query: 1046 LECGPHGRC--VGESCSCAAGWSGEFCSVRLC---------DARCA---EHG-QCK--NG 1088
             +C P  RC     +C C  G++G+ C+ RLC          A C    EH   C   NG
Sbjct: 120  CDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNG 179

Query: 1089 TCLCVSGWNGRHCTLEGCPRSCAGHG---QCRVDNDGRWE-----CKCFDGWDGPDCTTL 1140
             C C+ GW G HC  E CP+   G G    C   + G  +     C+C  G+ GP C +L
Sbjct: 180  ECSCLPGWAGLHCN-ESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL 238



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 83/258 (32%), Positives = 100/258 (38%), Gaps = 65/258 (25%)

Query: 888  CLMGH-CQCQPGFGGDDCSKSVCPVL--CSQRGEYIN--GECQCNPGWKGKECSLRHDE- 941
            C  G+   C P  GG   S   CP    C   G +    G C C PGW G  CSL   E 
Sbjct: 10   CSCGNNSSCDPKSGGT--SGFFCPSTHPCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEG 67

Query: 942  CEVPDCNGHGHCVNG--------KCSCVRGYKGKFCGEIDCP--------HPTCS----G 981
               P+C+    C NG        +C C  GY G  C E +CP          TC      
Sbjct: 68   FHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCRE-ECPVGRFGQDCAETCDCAPDA 126

Query: 982  HGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK 1041
              F   G C+C+ G+ G  C     D L C PD    G + +     SC A  +   C +
Sbjct: 127  RCFPANGACLCEHGFTGDRC----TDRL-C-PD----GFYGL-----SCQAPCT---CDR 168

Query: 1042 EVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL--------CDARC-AEHG---QCKNGT 1089
            E  SL C P     GE CSC  GW+G  C+           C   C   HG   Q  +G 
Sbjct: 169  EH-SLSCHPMN---GE-CSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGL 223

Query: 1090 CLCVSGWNGRHCTLEGCP 1107
            C C  G+ G HC    CP
Sbjct: 224  CQCAPGYTGPHCA-SLCP 240



 Score = 58.0 bits (134), Expect = 5e-07
 Identities = 38/122 (31%), Positives = 50/122 (40%), Gaps = 27/122 (22%)

Query: 882 CSGKGECLM--GHCQCQPGFGGDDCSKSVCP---------VLCSQRGEY------INGEC 924
           C+    C    G C C+ GF GD C+  +CP           C+   E+      +NGEC
Sbjct: 122 CAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGEC 181

Query: 925 QCNPGWKGKECSLR-HDECEVPDCNGHGHCV--------NGKCSCVRGYKGKFCGEIDCP 975
            C PGW G  C+     +   P C  H  C+        +G C C  GY G  C  + CP
Sbjct: 182 SCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL-CP 240

Query: 976 HP 977
            P
Sbjct: 241 PP 242


>AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein
            receptor related protein-deleted in tumor protein.
          Length = 4599

 Score = 83.0 bits (196), Expect = 1e-14
 Identities = 60/207 (28%), Positives = 80/207 (38%), Gaps = 24/207 (11%)

Query: 989  TCVCKKGWKGADCGTMDKDAL---QCLPDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKE 1042
            TCVC +G K    GT + D+L    C   C   G   ++ +    C C   +SGE C   
Sbjct: 4193 TCVCPEG-KYLINGTCNDDSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGERCEVN 4251

Query: 1043 VCSLECGPHGRCVGE-----SCSCAAGWSGEFCSVRLCDARCAEHGQC-----KNGTCLC 1092
             CS  C   G CV       +CSCA G++G  C   +C+  C   G C         C C
Sbjct: 4252 HCSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHC 4311

Query: 1093 VSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSR--- 1149
               + G  C    C   C     C + +DG  EC C   ++GP C   K   C       
Sbjct: 4312 QPEYTGDRCQYYVCHHYCVNSESCTIGDDGSXECVCPTRYEGPKCEVDKCVRCHGGHCII 4371

Query: 1150 DNDKDGLVDCEDPECCQSPACKSSQLC 1176
            + D + +  C    C       S QLC
Sbjct: 4372 NKDSEDIF-C---NCTNGKIASSCQLC 4394



 Score = 67.7 bits (158), Expect = 6e-10
 Identities = 58/189 (30%), Positives = 75/189 (39%), Gaps = 29/189 (15%)

Query: 873  EMTHNCPNGCSGKGECL---MGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYI-----NG 922
            E+ H C N C   G C+   +G   C C  GF G +C K+VC   C   G  I       
Sbjct: 4249 EVNH-CSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQP 4307

Query: 923  ECQCNPGWKGKECS--LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCS 980
             C C P + G  C   + H  C   +    G   + +C C   Y+G  C E+D     C 
Sbjct: 4308 YCHCQPEYTGDRCQYYVCHHYCVNSESCTIGDDGSXECVCPTRYEGPKC-EVD----KCV 4362

Query: 981  GHGFCIEGTCVCKKGWKGADCG-TMDKDALQC-LPD--CSGHGTFDVDTQT----CSCHA 1032
                C  G C+  K  +   C  T  K A  C L D  C   GT  +D +T    C C  
Sbjct: 4363 R---CHGGHCIINKDSEDIFCNCTNGKIASSCQLCDGYCYNGGTCQLDPETNVPVCLCST 4419

Query: 1033 KWSGEDCSK 1041
             WSG  C +
Sbjct: 4420 NWSGTQCER 4428



 Score = 66.5 bits (155), Expect = 1e-09
 Identities = 58/218 (26%), Positives = 78/218 (35%), Gaps = 33/218 (15%)

Query: 909  CPVLCSQRGEYINGE-----CQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG-----KC 958
            C + C   G  I  E     C C P + G+ C + H  C    C   G CV        C
Sbjct: 4217 CKLTCENGGRCILNEKGDLRCHCWPSYSGERCEVNH--CS-NYCQNGGTCVPSVLGRPTC 4273

Query: 959  SCVRGYKGKFCGEIDCPHPTCSGHGFCI-----EGTCVCKKGWKGADCGTMDKDALQCLP 1013
            SC  G+ G  CG+  C    C   G CI     +  C C+  + G  C            
Sbjct: 4274 SCALGFTGPNCGKTVC-EDFCQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVCHHYCVNS 4332

Query: 1014 DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES----CSCAAGWSGEF 1069
            +    G  D  +  C C  ++ G  C  + C    G H     +S    C+C  G     
Sbjct: 4333 ESCTIG--DDGSXECVCPTRYEGPKCEVDKCVRCHGGHCIINKDSEDIFCNCTNGKIASS 4390

Query: 1070 CSVRLCDARCAEHGQCKNG------TCLCVSGWNGRHC 1101
            C  +LCD  C   G C+         CLC + W+G  C
Sbjct: 4391 C--QLCDGYCYNGGTCQLDPETNVPVCLCSTNWSGTQC 4426



 Score = 40.7 bits (91), Expect = 0.078
 Identities = 76/276 (27%), Positives = 97/276 (35%), Gaps = 50/276 (18%)

Query: 882  CSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDE 941
            CS  G C+ GH  C    G +DC         +   E I+    CN    G E     D 
Sbjct: 1013 CSS-GRCIPGHWACD---GDNDCGDFSDEAQINCTKEEIHSPAGCN----GNEFQCHPDG 1064

Query: 942  CEVPDCNGHGHCVNGKCSCVRGYKGKFC-GEID-CPHPT---CSGHGFCIEGTCVCKKGW 996
              VPD      C +G+  C  G   K C G I  C H T   C   G CI    VC    
Sbjct: 1065 NCVPDL---WRC-DGEKDCEDGSDEKGCNGTIRLCDHKTKFSCWSTGRCINKAWVCDGDI 1120

Query: 997  KGADCGTMDK-DALQCLPD---CSGHGTFDVDTQTCSCHAKWSGEDCSKE--VCSLECGP 1050
               D    D  D+  C P    C+   +  +  +   C+ K    D S E  +C  EC  
Sbjct: 1121 DCEDQSDEDDCDSFLCGPPKHPCANDTSVCLQPEKL-CNGKKDCPDGSDEGYLCD-ECSL 1178

Query: 1051 HGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCK--NGTCLCVSGWNGRHCTLEGCPR 1108
            +       CS   G  G  CS       C E  Q    N TC  V  +   H     C +
Sbjct: 1179 NNGGCSNHCSVVPG-RGIVCS-------CPEGLQLNKDNKTCEIVD-YCSNHLK---CSQ 1226

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGW----DGPDCTTL 1140
             C  H           +C C++GW    DG  CT++
Sbjct: 1227 VCEQHKHTV-------KCSCYEGWKLDVDGESCTSV 1255



 Score = 39.5 bits (88), Expect = 0.18
 Identities = 72/281 (25%), Positives = 96/281 (34%), Gaps = 52/281 (18%)

Query: 909  CPVLCSQRGEYINGECQCN-PGW--KGK-ECSLRHDE--CEVPDC-NGHGHCV-NGKCSC 960
            CP    Q G +  G   C  P +   G+ +C    DE  C+   C +G   C  N KC  
Sbjct: 3352 CPEFRCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIP 3411

Query: 961  V--RGYKGKFCG----EIDCPHPTCSGHGFCIEGTCVC-KKGW---KGADCGTMDKDALQ 1010
            V  R      CG    E DCP  +CS   F  + T  C  K W   +  DC     +A  
Sbjct: 3412 VNLRCNGQDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEA-N 3470

Query: 1011 CLPDCSGHGTFDVDTQTC-----------SCHAKWSGEDCSKEVCSLE---CGPHGRCVG 1056
            C     G   F      C            C      E+C  + C+L+   C  +G CV 
Sbjct: 3471 CDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLCA-NGDCVS 3529

Query: 1057 ESCSCAAGWS-GEFCSVRLCDARCA-EHGQCKNGTCL-----------CVSGWNGRHC-- 1101
                C   +   +    R C+  C+ +  +C NG C+           C  G + + C  
Sbjct: 3530 SRFWCDGDFDCADGSDERNCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEP 3589

Query: 1102 ---TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
               T       CA  G          E  C DG D  DC T
Sbjct: 3590 ASPTCSSREYICASDGCISASLKCNGEYDCADGSDEMDCVT 3630


>Z12172-1|CAA78163.1|  383|Homo sapiens putative homeotic protein
            protein.
          Length = 383

 Score = 82.2 bits (194), Expect = 3e-14
 Identities = 54/160 (33%), Positives = 69/160 (43%), Gaps = 19/160 (11%)

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE--SCSCAAGWSG 1067
            +C P C+    F  D   C CH  W G  C + V S  C  HG C GE   C C  GW G
Sbjct: 25   ECFPACNPQNGFCEDDNVCRCHVGWQGPLCDQCVTSPGC-LHGLC-GEPGQCICTDGWDG 82

Query: 1068 EFC--SVRLC-DARCAEHGQCKN-----GTCLCVSGWNGRHCTLEGCPRSCAG----HGQ 1115
            E C   VR C  A CA +G C +       C C  G++G+ C  +  P    G    HG 
Sbjct: 83   ELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGG 142

Query: 1116 CRVDNDGR---WECKCFDGWDGPDCTTLKEQICDDSRDND 1152
              VD++GR     C C  G+ G  C  +      +  +ND
Sbjct: 143  TCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCEND 182



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 58/187 (31%), Positives = 79/187 (42%), Gaps = 33/187 (17%)

Query: 977  PTCSG-HGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKW 1034
            P C+  +GFC +   C C  GW+G  C     D     P C  HG      Q C C   W
Sbjct: 28   PACNPQNGFCEDDNVCRCHVGWQGPLC-----DQCVTSPGCL-HGLCGEPGQ-CICTDGW 80

Query: 1035 SGEDCSKEV--C-SLECGPHGRCVG-----ESCSCAAGWSGEFCSVR-----LCDARCAE 1081
             GE C ++V  C S  C  +G CV        CSCA G+SG+ C  +     +  + C  
Sbjct: 81   DGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQH 140

Query: 1082 HGQC-------KNGTCLCVSGWNGRHCTL--EGC-PRSCAGHGQCRVDNDGRWECKCFDG 1131
             G C        + +CLC  G++G  C +    C P  C   G C  D  G + C+C  G
Sbjct: 141  GGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC-TDIGGDFRCRCPAG 199

Query: 1132 WDGPDCT 1138
            +    C+
Sbjct: 200  FIDKTCS 206



 Score = 70.5 bits (165), Expect = 8e-11
 Identities = 58/205 (28%), Positives = 80/205 (39%), Gaps = 30/205 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C+C  G+ G  C + V    C        G+C C  GW G+ C      C    C  +G 
Sbjct: 43   CRCHVGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGT 102

Query: 953  CVN-----GKCSCVRGYKGKFCGEIDCP----HPTCSGHGFCIE-------GTCVCKKGW 996
            CV+      +CSC  GY GK C + D P       C   G C++        +C+C  G+
Sbjct: 103  CVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162

Query: 997  KGADCGTMDKDALQCLPD-CSGHGT-FDVDTQ-TCSCHAKWSGEDCSKEV---CSLECGP 1050
             G  C  +   A  C P+ C   G   D+     C C A +  + CS+ V    S  C  
Sbjct: 163  SGNFCEIV---ANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQN 219

Query: 1051 HGRC-----VGESCSCAAGWSGEFC 1070
             G C     V   C C   ++G  C
Sbjct: 220  GGTCLQHTQVSYECLCKPEFTGLTC 244



 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 30/179 (16%)

Query: 891  GHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYIN-----GECQCNPGWKGKECSLRHDEC 942
            G C C  G+ G+ C + V  C    C+  G  ++      EC C PG+ GK+C  +   C
Sbjct: 72   GQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPC 131

Query: 943  EV--PDCNGHGHCV-------NGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFC--IEG- 988
             +    C   G CV       +  C C  G+ G FC  +   C    C   G C  I G 
Sbjct: 132  VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGD 191

Query: 989  -TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDTQT---CSCHAKWSGEDCSKE 1042
              C C  G+    C    +    C    C   GT    TQ    C C  +++G  C K+
Sbjct: 192  FRCRCPAGFIDKTC---SRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKK 247



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 29/97 (29%), Positives = 38/97 (39%), Gaps = 12/97 (12%)

Query: 885 KGECLMGHCQCQPGFGGDDC---SKSVCPVLCSQRG--EYINGE--CQCNPGWKGKECSL 937
           +G      C C PGF G+ C   + S  P  C   G    I G+  C+C  G+  K CS 
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207

Query: 938 RHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFC 969
               C    C   G C     V+ +C C   + G  C
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244


>D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein.
          Length = 2589

 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 69/231 (29%), Positives = 101/231 (43%), Gaps = 50/231 (21%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCG--EIDCPHPTCSG-----HGFCIEG-----T 989
            C+GHG C +     G+C C  G+ G  C   E+    P C+G     HG C EG     +
Sbjct: 1359 CSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGS 1418

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDT---QTCSCHAKWSGED--CSK-EV 1043
            CVC  GW+G  C        QC   C  +     D+    TC+C A +SG    CS+ + 
Sbjct: 1419 CVCNVGWQGLRCDQKITSP-QCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDP 1477

Query: 1044 CSLE---CGPHGRCV----GE-SCSCAAGW--SGEFCS-VRLC---DARCAEHGQC---- 1085
            C+     C PH  C     G+ +C+C  G+   GE C  +  C      C  H +C    
Sbjct: 1478 CAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTG 1537

Query: 1086 -KNGTCLCVSGWNG---RHCTL-EGCPRS---CAGHGQCRVDNDGRWECKC 1128
             +  +C C  G++G   R C L + C ++   C+ +  C+   DG+  C C
Sbjct: 1538 PQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1588



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 65/222 (29%), Positives = 90/222 (40%), Gaps = 46/222 (20%)

Query: 960  CVRGYKGKFCGEIDCPHP---TCSGHGFCIE-----GTCVCKKGWKGADCGTMDKDALQC 1011
            C  G+ G  C    CP      CSGHG C +     G C C +G+ G  C   +      
Sbjct: 1339 CCPGFFGTLCEP--CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYG- 1395

Query: 1012 LPDCSG-----HGTFDVDTQ---TCSCHAKWSGEDCSKEV----CSLECGPHGRCVGES- 1058
             P+C+G     HG      Q   +C C+  W G  C +++    C  +C P+  CV +S 
Sbjct: 1396 -PNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSA 1454

Query: 1059 ----CSCAAGWSGE--FCS-VRLC---DARCAEHGQCK-----NGTCLCVSGW--NGRHC 1101
                C+CAAG+SG   FCS V  C      C+ H  C        TC C  G+  +G  C
Sbjct: 1455 GASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELC 1514

Query: 1102 -TLEGC---PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
              +  C      C  H +C      +  C C +G+ G    T
Sbjct: 1515 QEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT 1556



 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 63/207 (30%), Positives = 91/207 (43%), Gaps = 43/207 (20%)

Query: 959  SCVRGYKGKFCGEIDCP---HPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQ 1010
            +C  GY G  C E  CP      C+GHG C++G     TCVC++ ++G+ C    +D  +
Sbjct: 118  ACCPGYWGSRCHE--CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQEC-QDPNR 174

Query: 1011 CLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFC 1070
              PDC            CSC            VC+   GP G     SC C AG++G  C
Sbjct: 175  FGPDCQS---------VCSC---------VHGVCNH--GPRG---DGSCLCFAGYTGPHC 211

Query: 1071 SVRL--C-DARCAEHGQC--KNGTCLCVSGWN--GRHCTLEG-C-PRSCAGHGQCRVDND 1121
               L  C + RC ++ QC  +  +C C+ G+   G  C     C P  C+   QC V   
Sbjct: 212  DQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPK 271

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDDS 1148
            G+ +C C + + G     L +  C D+
Sbjct: 272  GQAQCHCPENYHGDGMVCLPKDPCTDN 298



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 78/266 (29%), Positives = 101/266 (37%), Gaps = 66/266 (24%)

Query: 878  CPNG----CSGKGECL-----MGHCQCQPGFGGDDCSKSV-------CPVLCS------Q 915
            CP G    CSG G+C       G C C  GF G  C           C  +C       Q
Sbjct: 1351 CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQ 1410

Query: 916  RGEYINGECQCNPGWKGKECSLRHDECEVP-DCNGHGHCVN-----GKCSCVRGYKGK-- 967
             G   +G C CN GW+G  C  +    + P  C+ + +CV        C+C  GY G   
Sbjct: 1411 EGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGI 1470

Query: 968  FCGEID-CP--HPTCSGHGFCI-----EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHG 1019
            FC E+D C   H  CS H  C      + TC C+ G+ G   G + ++   CL     HG
Sbjct: 1471 FCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGD--GELCQEINSCL---IHHG 1525

Query: 1020 TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE-FCSVRLCDAR 1078
                    C  HA              EC P G     SCSC  G+SG+   +  L D  
Sbjct: 1526 -------GCHIHA--------------ECIPTGP-QQVSCSCREGYSGDGIRTCELLDPC 1563

Query: 1079 CAEHGQCKNGTCLCVSGWNGRHCTLE 1104
               +G C        +G   R CT +
Sbjct: 1564 SKNNGGCSPYATCKSTGDGQRTCTCD 1589



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 85/313 (27%), Positives = 122/313 (38%), Gaps = 65/313 (20%)

Query: 878  CPNGCSGK-GECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            CP+G   +  + +   C+ +   GG   S S C   C  R + +   C C PG+ G  C 
Sbjct: 74   CPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKC--RKQVVQKAC-C-PGYWGSRCH 129

Query: 937  LRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGKFCGEIDCPH---PTCSG-----HG 983
                  E P CNGHG C+     NG C C   ++G  C E   P+   P C       HG
Sbjct: 130  ECPGGAETP-CNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG 188

Query: 984  FCI-----EGTCVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFDVDTQTCSCHAKWS-- 1035
             C      +G+C+C  G+ G  C   D++   C    C  +     +  +C C   ++  
Sbjct: 189  VCNHGPRGDGSCLCFAGYTGPHC---DQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQ 245

Query: 1036 GEDCSK------EVCSL--ECG--PHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH-GQ 1084
            G +C          CSL  +C   P G+     C C   + G+   V L    C ++ G 
Sbjct: 246  GSECRAPNPCWPSPCSLLAQCSVSPKGQA---QCHCPENYHGDGM-VCLPKDPCTDNLGG 301

Query: 1085 CKNGTCLCVSGWNGR-HCTLE------------GC-----PRSCAGHGQCRVDNDGRWEC 1126
            C + + LCV    G+  CT              GC     P SC     C+V  DG+  C
Sbjct: 302  CPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSC 361

Query: 1127 KCFDG--WDGPDC 1137
             C +    DG  C
Sbjct: 362  VCRESEVGDGRAC 374



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 63/211 (29%), Positives = 86/211 (40%), Gaps = 31/211 (14%)

Query: 878  CPNGCSGKGECLMGH------CQ-CQPGFGGDDCSKSVCPV--LCSQRGEYINGECQCNP 928
            C +G SG G+CL         C+ C PG  G  C    C V   C + G   +G C C+ 
Sbjct: 2004 CMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDE-GLGGSGSCFCDE 2062

Query: 929  GWKGKECSLRHDECEV--PDCNGHGHCVNG-KCSCVRGYK--GKFCGEID-CP--HPTCS 980
            GW G  C ++ +   V  P C     C  G  C C  GY+  G+ C   D C   H  CS
Sbjct: 2063 GWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCS 2122

Query: 981  GHGFCIE----GTCVCKKGWKGA--DCGTMDKDALQCLPDCSGHG---TFDVDTQTCSCH 1031
             H  C +     TC C   ++G    C   +         CS H    +  ++T+ C CH
Sbjct: 2123 EHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECH 2182

Query: 1032 AKWSGEDCSKEVCSLECGPH-GRCVGESCSC 1061
            A + G+      C  E  P   RC+G+   C
Sbjct: 2183 AGYVGDGLQ---CLEESEPPVDRCLGQPPPC 2210



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 83/272 (30%), Positives = 110/272 (40%), Gaps = 59/272 (21%)

Query: 895  CQPGFGGDDCSKSVCPV----LCSQRGEYI-----NGECQCNPGWKGKECSL-----RHD 940
            C  GF G DC++  CP      C  +G        NG C C P +KG  C +     +H 
Sbjct: 739  CCKGFFGPDCTQ--CPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHG 796

Query: 941  ECEVPDCN-GHGHCVN-----GKC---SCVRGYKGKFCGEI--DCPHPT-----CSGHGF 984
            E    DC   HG C N     G C   +C  G+ G+FC E   DC  PT     C  H  
Sbjct: 797  EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC-GPTGLAQHCHLHAR 855

Query: 985  CI--EGT--CVCKKGWK--GADCGTMDKDALQCLPDCSGHGTF---DVDTQTCSCHAKWS 1035
            C+  EG   C C  G++  G  C   +  +      CS +       + T  C+CH  WS
Sbjct: 856  CVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWS 915

Query: 1036 GED--C-SKEVCSLE----CGPHGRC----VGES-CSCAAGWSGEFCSVRLCDARCAEHG 1083
            G+   C + + C L+    C     C     G+S C+C  G++G+       D   A +G
Sbjct: 916  GDGRVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNG 975

Query: 1084 QCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
             C    TC  V G   R CT   CP    G G
Sbjct: 976  GCHGLATCRAVGG-GQRVCT---CPPGFGGDG 1003



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 62/206 (30%), Positives = 85/206 (41%), Gaps = 38/206 (18%)

Query: 948  NGHGHCVNGKC-SCVRGYKGKFCGEI-DCPHPTC---SGHGFCIEGTCVCKKGWKGADC- 1001
            + H   +  KC +C R ++     ++ D P  +C   SG  F    +  C K  +  DC 
Sbjct: 1281 HSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCC 1340

Query: 1002 ----GTMDKDALQCLPD-CSGHGTFD---VDTQTCSCHAKWSGEDCSKEVCSLECGPHG- 1052
                GT+ +     L   CSGHG      + +  C CH  + G  C  EVC L  G +G 
Sbjct: 1341 PGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTAC--EVCEL--GRYGP 1396

Query: 1053 RCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHC----TLEGCPR 1108
             C G  C CA G         LC     + G   +G+C+C  GW G  C    T   CPR
Sbjct: 1397 NCTGV-CDCAHG---------LC-----QEGLQGDGSCVCNVGWQGLRCDQKITSPQCPR 1441

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGWDG 1134
             C  +  C  D+ G   C C  G+ G
Sbjct: 1442 KCDPNANCVQDSAGASTCACAAGYSG 1467



 Score = 61.3 bits (142), Expect = 5e-08
 Identities = 66/239 (27%), Positives = 86/239 (35%), Gaps = 43/239 (17%)

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNG-----KCSCVRGYKGKFC-----GEID-- 973
            C PG  G EC         P C+  G C++G     +C C  G+ G  C     G     
Sbjct: 1978 CCPGHYGSECQACPGGPSSP-CSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPH 2036

Query: 974  CPHPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTC 1028
            C    C+ HG C EG     +C C +GW G  C    +    C P C+            
Sbjct: 2037 CQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAV-------- 2088

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C A   G  C    CSL     GR    +  C  G  G  CS     A C++ G     
Sbjct: 2089 -CRA---GNSCE---CSLGYEGDGRVCTVADLCQDGHGG--CSEH---ANCSQVGTMVTC 2136

Query: 1089 TCLC---VSGWN--GRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
            TCL      GW+   R+   +G    C+ H  C         C+C  G+ G     L+E
Sbjct: 2137 TCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEE 2195



 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 66/240 (27%), Positives = 93/240 (38%), Gaps = 49/240 (20%)

Query: 877  NCPNGCSGKGECL--------MGHCQCQPGFGGDDCSKSVCPV--LCSQRGEYINGECQ- 925
            NC +G  G G CL          H    P   G+ C +    V  LC  R     G CQ 
Sbjct: 764  NCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNR-PGSGGVCQQ 822

Query: 926  --CNPGWKGKECSLRHDECE----VPDCNGHGHCVN----GKCSCVRGYKGK--FCGEID 973
              C PG+ G+ C+    +C        C+ H  CV+     +C C+ G++G    C   +
Sbjct: 823  GTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSN 882

Query: 974  -CPHPT---CSGHGFCIEGT-----CVCKKGWKGAD--CGTMDKDALQCLPDCSGHGTFD 1022
             C HP    CS +  C+ G+     C C KGW G    C  +D+  L     C       
Sbjct: 883  PCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDVRGGCHTDALCS 942

Query: 1023 V---DTQTCSCHAKWSGE--DCSK-EVCSL-ECGPHG----RCVG---ESCSCAAGWSGE 1068
                    C+C   ++G+   CS  + C     G HG    R VG     C+C  G+ G+
Sbjct: 943  YVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGD 1002



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 50/159 (31%), Positives = 61/159 (38%), Gaps = 30/159 (18%)

Query: 992  CKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSLEC 1048
            C KG+ G DC T           C G G      Q    C C   + G  C   +CS   
Sbjct: 739  CCKGFFGPDC-TQCPGGFS--NPCYGKGNCSDGIQGNGACLCFPDYKGIAC--HICS-NP 792

Query: 1049 GPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE---- 1104
              HG    E C C  G         LCD R    G C+ GT  C  G++GR C       
Sbjct: 793  NKHGEQCQEDCGCVHG---------LCDNRPGSGGVCQQGT--CAPGFSGRFCNESMGDC 841

Query: 1105 ---GCPRSCAGHGQCRVDNDGRWECKCFDGW--DGPDCT 1138
               G  + C  H +C V  +G   C+C DG+  DG  CT
Sbjct: 842  GPTGLAQHCHLHARC-VSQEGVARCRCLDGFEGDGFSCT 879



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 61/220 (27%), Positives = 82/220 (37%), Gaps = 42/220 (19%)

Query: 885  KGECLMGH----CQCQPGFGGDDCS-KSVCPVLCSQRGEYINGECQCNPGWKGKECSL-- 937
            K  C  GH    CQ  PG     CS + VC       G   +G+C C  G+ G  C L  
Sbjct: 1975 KPSCCPGHYGSECQACPGGPSSPCSDRGVC-----MDGMSGSGQCLCRSGFAGTACELCA 2029

Query: 938  ---RHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEIDCP-----HPTCSGHGF 984
                   C+   C  HG C      +G C C  G+ G  C E+         P C+    
Sbjct: 2030 PGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC-EVQLELQPVCTPPCAPEAV 2088

Query: 985  CIEG-TCVCKKGWKGADCGTMDKDALQ-CLPDCSGHGT-FDVDTQ-TCSCHAKWSGE--D 1038
            C  G +C C  G++G        D  Q     CS H     V T  TC+C   + G+   
Sbjct: 2089 CRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWS 2148

Query: 1039 C-SKEVCS----LECGPHGRCVG-----ESCSCAAGWSGE 1068
            C ++  C+      C  H  C+        C C AG+ G+
Sbjct: 2149 CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGD 2188



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 63/237 (26%), Positives = 89/237 (37%), Gaps = 45/237 (18%)

Query: 933  KECSLRHDECEV----PDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP---HPTCSGHGFC 985
            KEC   HD   +      C  + +    +  C +G+ G  C +  CP      C G G C
Sbjct: 708  KECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKGFFGPDCTQ--CPGGFSNPCYGKGNC 765

Query: 986  IEG-----TCVCKKGWKGADC---GTMDKDALQCLPDCSG-HGTFDVDTQTCSCHAKWSG 1036
             +G      C+C   +KG  C      +K   QC  DC   HG  D        +   SG
Sbjct: 766  SDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCD--------NRPGSG 817

Query: 1037 EDCSKEVCSLECGPHGRCVGESCS-CAAGWSGEFCSVRLCDARC-AEHGQCKNGTCLCVS 1094
              C +  C+   G  GR   ES   C      + C +    ARC ++ G  +   C C+ 
Sbjct: 818  GVCQQGTCAP--GFSGRFCNESMGDCGPTGLAQHCHLH---ARCVSQEGVAR---CRCLD 869

Query: 1095 GWNGR--HCTLEG-CPR----SCAGHGQCRVDNDGRWECKCFDGW--DGPDCTTLKE 1142
            G+ G    CT    C       C+ + +C   + G   C C  GW  DG  C  + E
Sbjct: 870  GFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDE 926



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/164 (26%), Positives = 56/164 (34%), Gaps = 27/164 (16%)

Query: 876  HNCPNG----CSGKGECL-----MGHCQCQPGFGGDDCSKSV--------CPVLCS---- 914
            H CP G    C+G G CL      G C CQ  F G  C +          C  +CS    
Sbjct: 129  HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG 188

Query: 915  --QRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHC--VNGKCSCVRGYKGKFCG 970
                G   +G C C  G+ G  C      C+   C  +  C      C C+ GY  +   
Sbjct: 189  VCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQ-GS 247

Query: 971  EIDCPHPTCSGHGFCIEGTCVCKKGWKGADC-GTMDKDALQCLP 1013
            E   P+P        +    V  KG     C      D + CLP
Sbjct: 248  ECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLP 291



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 35/108 (32%), Positives = 43/108 (39%), Gaps = 21/108 (19%)

Query: 1049 GPHGRCVGESC--SCAAGWSGEFCSVRLC----DARCAEHGQCKNGT-----CLCVSGWN 1097
            G H  CV  +   SC  G  G  C    C     + C++ G C +G      CLC SG+ 
Sbjct: 1964 GCHRNCVTTTWKPSCCPGHYGSECQA--CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFA 2021

Query: 1098 GRHCTL-------EGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G  C L         C    C  HG+C     G   C C +GW GP C
Sbjct: 2022 GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC 2069



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 43/164 (26%), Positives = 63/164 (38%), Gaps = 18/164 (10%)

Query: 1019 GTFDVDTQTC-SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDA 1077
            G   V +  C   HA+   E C        C   G  + ++   +  +   F   R C  
Sbjct: 1270 GVLTVGSSRCLHSHAEALREKCVNCTRRFRC-TQGFQLQDTPRKSCVYRSGFSFSRGCSY 1328

Query: 1078 RCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS----CAGHGQCRVDNDGRWECKCFDGWD 1133
             CA+  Q  +    C  G+ G  C  E CP      C+GHGQC+    G  EC C +G+ 
Sbjct: 1329 TCAKKIQVPD----CCPGFFGTLC--EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFH 1382

Query: 1134 GPDCTTLKEQICDDSRDNDK-DGLVDCEDPECCQSPACKSSQLC 1176
            G  C     ++C+  R      G+ DC    C +      S +C
Sbjct: 1383 GTAC-----EVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVC 1421



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 40/127 (31%), Positives = 52/127 (40%), Gaps = 17/127 (13%)

Query: 1024 DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHG 1083
            DT   SC  + SG   S+  CS  C    + V + C    G   E C   L    C+ HG
Sbjct: 1308 DTPRKSCVYR-SGFSFSRG-CSYTCAKKIQ-VPDCCPGFFGTLCEPCPGGLGGV-CSGHG 1363

Query: 1084 QCKN-----GTCLCVSGWNGRHCTLEGCPR---SCAG-----HGQCRVDNDGRWECKCFD 1130
            QC++     G C C  G++G  C +    R   +C G     HG C+    G   C C  
Sbjct: 1364 QCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNV 1423

Query: 1131 GWDGPDC 1137
            GW G  C
Sbjct: 1424 GWQGLRC 1430



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 32/125 (25%), Positives = 40/125 (32%), Gaps = 11/125 (8%)

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR-HCTLEGCPRSCAGH 1113
            + + C       G   S+  C  +C +  Q     C C   W  R H    G    C GH
Sbjct: 86   ITQDCRYEVQLGGSMVSMSGCRRKCRK--QVVQKAC-CPGYWGSRCHECPGGAETPCNGH 142

Query: 1114 GQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSR--DNDKDGLVDCEDPECCQSPACK 1171
            G C    D    C C + + G  C     Q C D      D   +  C    C   P   
Sbjct: 143  GTCLDGMDRNGTCVCQENFRGSAC-----QECQDPNRFGPDCQSVCSCVHGVCNHGPRGD 197

Query: 1172 SSQLC 1176
             S LC
Sbjct: 198  GSCLC 202


>DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein.
          Length = 2570

 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 69/231 (29%), Positives = 101/231 (43%), Gaps = 50/231 (21%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCG--EIDCPHPTCSG-----HGFCIEG-----T 989
            C+GHG C +     G+C C  G+ G  C   E+    P C+G     HG C EG     +
Sbjct: 1340 CSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGS 1399

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDT---QTCSCHAKWSGED--CSK-EV 1043
            CVC  GW+G  C        QC   C  +     D+    TC+C A +SG    CS+ + 
Sbjct: 1400 CVCNVGWQGLRCDQKITSP-QCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDP 1458

Query: 1044 CSLE---CGPHGRCV----GE-SCSCAAGW--SGEFCS-VRLC---DARCAEHGQC---- 1085
            C+     C PH  C     G+ +C+C  G+   GE C  +  C      C  H +C    
Sbjct: 1459 CAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTG 1518

Query: 1086 -KNGTCLCVSGWNG---RHCTL-EGCPRS---CAGHGQCRVDNDGRWECKC 1128
             +  +C C  G++G   R C L + C ++   C+ +  C+   DG+  C C
Sbjct: 1519 PQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 65/222 (29%), Positives = 90/222 (40%), Gaps = 46/222 (20%)

Query: 960  CVRGYKGKFCGEIDCPHP---TCSGHGFCIE-----GTCVCKKGWKGADCGTMDKDALQC 1011
            C  G+ G  C    CP      CSGHG C +     G C C +G+ G  C   +      
Sbjct: 1320 CCPGFFGTLCEP--CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYG- 1376

Query: 1012 LPDCSG-----HGTFDVDTQ---TCSCHAKWSGEDCSKEV----CSLECGPHGRCVGES- 1058
             P+C+G     HG      Q   +C C+  W G  C +++    C  +C P+  CV +S 
Sbjct: 1377 -PNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSA 1435

Query: 1059 ----CSCAAGWSGE--FCS-VRLC---DARCAEHGQCK-----NGTCLCVSGW--NGRHC 1101
                C+CAAG+SG   FCS V  C      C+ H  C        TC C  G+  +G  C
Sbjct: 1436 GASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELC 1495

Query: 1102 -TLEGC---PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
              +  C      C  H +C      +  C C +G+ G    T
Sbjct: 1496 QEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT 1537



 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 63/207 (30%), Positives = 91/207 (43%), Gaps = 43/207 (20%)

Query: 959  SCVRGYKGKFCGEIDCP---HPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQ 1010
            +C  GY G  C E  CP      C+GHG C++G     TCVC++ ++G+ C    +D  +
Sbjct: 99   ACCPGYWGSRCHE--CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQEC-QDPNR 155

Query: 1011 CLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFC 1070
              PDC            CSC            VC+   GP G     SC C AG++G  C
Sbjct: 156  FGPDCQS---------VCSC---------VHGVCNH--GPRG---DGSCLCFAGYTGPHC 192

Query: 1071 SVRL--C-DARCAEHGQC--KNGTCLCVSGWN--GRHCTLEG-C-PRSCAGHGQCRVDND 1121
               L  C + RC ++ QC  +  +C C+ G+   G  C     C P  C+   QC V   
Sbjct: 193  DQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPK 252

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDDS 1148
            G+ +C C + + G     L +  C D+
Sbjct: 253  GQAQCHCPENYHGDGMVCLPKDPCTDN 279



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 78/266 (29%), Positives = 101/266 (37%), Gaps = 66/266 (24%)

Query: 878  CPNG----CSGKGECL-----MGHCQCQPGFGGDDCSKSV-------CPVLCS------Q 915
            CP G    CSG G+C       G C C  GF G  C           C  +C       Q
Sbjct: 1332 CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQ 1391

Query: 916  RGEYINGECQCNPGWKGKECSLRHDECEVP-DCNGHGHCVN-----GKCSCVRGYKGK-- 967
             G   +G C CN GW+G  C  +    + P  C+ + +CV        C+C  GY G   
Sbjct: 1392 EGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGI 1451

Query: 968  FCGEID-CP--HPTCSGHGFCI-----EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHG 1019
            FC E+D C   H  CS H  C      + TC C+ G+ G   G + ++   CL     HG
Sbjct: 1452 FCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGD--GELCQEINSCL---IHHG 1506

Query: 1020 TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE-FCSVRLCDAR 1078
                    C  HA              EC P G     SCSC  G+SG+   +  L D  
Sbjct: 1507 -------GCHIHA--------------ECIPTGP-QQVSCSCREGYSGDGIRTCELLDPC 1544

Query: 1079 CAEHGQCKNGTCLCVSGWNGRHCTLE 1104
               +G C        +G   R CT +
Sbjct: 1545 SKNNGGCSPYATCKSTGDGQRTCTCD 1570



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 85/313 (27%), Positives = 122/313 (38%), Gaps = 65/313 (20%)

Query: 878  CPNGCSGK-GECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            CP+G   +  + +   C+ +   GG   S S C   C  R + +   C C PG+ G  C 
Sbjct: 55   CPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKC--RKQVVQKAC-C-PGYWGSRCH 110

Query: 937  LRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGKFCGEIDCPH---PTCSG-----HG 983
                  E P CNGHG C+     NG C C   ++G  C E   P+   P C       HG
Sbjct: 111  ECPGGAETP-CNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG 169

Query: 984  FCI-----EGTCVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFDVDTQTCSCHAKWS-- 1035
             C      +G+C+C  G+ G  C   D++   C    C  +     +  +C C   ++  
Sbjct: 170  VCNHGPRGDGSCLCFAGYTGPHC---DQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQ 226

Query: 1036 GEDCSK------EVCSL--ECG--PHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH-GQ 1084
            G +C          CSL  +C   P G+     C C   + G+   V L    C ++ G 
Sbjct: 227  GSECRAPNPCWPSPCSLLAQCSVSPKGQA---QCHCPENYHGDGM-VCLPKDPCTDNLGG 282

Query: 1085 CKNGTCLCVSGWNGR-HCTLE------------GC-----PRSCAGHGQCRVDNDGRWEC 1126
            C + + LCV    G+  CT              GC     P SC     C+V  DG+  C
Sbjct: 283  CPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSC 342

Query: 1127 KCFDG--WDGPDC 1137
             C +    DG  C
Sbjct: 343  VCRESEVGDGRAC 355



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 63/211 (29%), Positives = 86/211 (40%), Gaps = 31/211 (14%)

Query: 878  CPNGCSGKGECLMGH------CQ-CQPGFGGDDCSKSVCPV--LCSQRGEYINGECQCNP 928
            C +G SG G+CL         C+ C PG  G  C    C V   C + G   +G C C+ 
Sbjct: 1985 CMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDE-GLGGSGSCFCDE 2043

Query: 929  GWKGKECSLRHDECEV--PDCNGHGHCVNG-KCSCVRGYK--GKFCGEID-CP--HPTCS 980
            GW G  C ++ +   V  P C     C  G  C C  GY+  G+ C   D C   H  CS
Sbjct: 2044 GWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCS 2103

Query: 981  GHGFCIE----GTCVCKKGWKGA--DCGTMDKDALQCLPDCSGHG---TFDVDTQTCSCH 1031
             H  C +     TC C   ++G    C   +         CS H    +  ++T+ C CH
Sbjct: 2104 EHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECH 2163

Query: 1032 AKWSGEDCSKEVCSLECGPH-GRCVGESCSC 1061
            A + G+      C  E  P   RC+G+   C
Sbjct: 2164 AGYVGDGLQ---CLEESEPPVDRCLGQPPPC 2191



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 83/272 (30%), Positives = 110/272 (40%), Gaps = 59/272 (21%)

Query: 895  CQPGFGGDDCSKSVCPV----LCSQRGEYI-----NGECQCNPGWKGKECSL-----RHD 940
            C  GF G DC++  CP      C  +G        NG C C P +KG  C +     +H 
Sbjct: 720  CCKGFFGPDCTQ--CPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHG 777

Query: 941  ECEVPDCN-GHGHCVN-----GKC---SCVRGYKGKFCGEI--DCPHPT-----CSGHGF 984
            E    DC   HG C N     G C   +C  G+ G+FC E   DC  PT     C  H  
Sbjct: 778  EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC-GPTGLAQHCHLHAR 836

Query: 985  CI--EGT--CVCKKGWK--GADCGTMDKDALQCLPDCSGHGTF---DVDTQTCSCHAKWS 1035
            C+  EG   C C  G++  G  C   +  +      CS +       + T  C+CH  WS
Sbjct: 837  CVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWS 896

Query: 1036 GED--C-SKEVCSLE----CGPHGRC----VGES-CSCAAGWSGEFCSVRLCDARCAEHG 1083
            G+   C + + C L+    C     C     G+S C+C  G++G+       D   A +G
Sbjct: 897  GDGRVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNG 956

Query: 1084 QCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
             C    TC  V G   R CT   CP    G G
Sbjct: 957  GCHGLATCRAVGG-GQRVCT---CPPGFGGDG 984



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 62/206 (30%), Positives = 85/206 (41%), Gaps = 38/206 (18%)

Query: 948  NGHGHCVNGKC-SCVRGYKGKFCGEI-DCPHPTC---SGHGFCIEGTCVCKKGWKGADC- 1001
            + H   +  KC +C R ++     ++ D P  +C   SG  F    +  C K  +  DC 
Sbjct: 1262 HSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCC 1321

Query: 1002 ----GTMDKDALQCLPD-CSGHGTFD---VDTQTCSCHAKWSGEDCSKEVCSLECGPHG- 1052
                GT+ +     L   CSGHG      + +  C CH  + G  C  EVC L  G +G 
Sbjct: 1322 PGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTAC--EVCEL--GRYGP 1377

Query: 1053 RCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHC----TLEGCPR 1108
             C G  C CA G         LC     + G   +G+C+C  GW G  C    T   CPR
Sbjct: 1378 NCTGV-CDCAHG---------LC-----QEGLQGDGSCVCNVGWQGLRCDQKITSPQCPR 1422

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGWDG 1134
             C  +  C  D+ G   C C  G+ G
Sbjct: 1423 KCDPNANCVQDSAGASTCACAAGYSG 1448



 Score = 61.3 bits (142), Expect = 5e-08
 Identities = 66/239 (27%), Positives = 86/239 (35%), Gaps = 43/239 (17%)

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNG-----KCSCVRGYKGKFC-----GEID-- 973
            C PG  G EC         P C+  G C++G     +C C  G+ G  C     G     
Sbjct: 1959 CCPGHYGSECQACPGGPSSP-CSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPH 2017

Query: 974  CPHPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTC 1028
            C    C+ HG C EG     +C C +GW G  C    +    C P C+            
Sbjct: 2018 CQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAV-------- 2069

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C A   G  C    CSL     GR    +  C  G  G  CS     A C++ G     
Sbjct: 2070 -CRA---GNSCE---CSLGYEGDGRVCTVADLCQDGHGG--CSEH---ANCSQVGTMVTC 2117

Query: 1089 TCLC---VSGWN--GRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
            TCL      GW+   R+   +G    C+ H  C         C+C  G+ G     L+E
Sbjct: 2118 TCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEE 2176



 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 66/240 (27%), Positives = 93/240 (38%), Gaps = 49/240 (20%)

Query: 877  NCPNGCSGKGECL--------MGHCQCQPGFGGDDCSKSVCPV--LCSQRGEYINGECQ- 925
            NC +G  G G CL          H    P   G+ C +    V  LC  R     G CQ 
Sbjct: 745  NCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNR-PGSGGVCQQ 803

Query: 926  --CNPGWKGKECSLRHDECE----VPDCNGHGHCVN----GKCSCVRGYKGK--FCGEID 973
              C PG+ G+ C+    +C        C+ H  CV+     +C C+ G++G    C   +
Sbjct: 804  GTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSN 863

Query: 974  -CPHPT---CSGHGFCIEGT-----CVCKKGWKGAD--CGTMDKDALQCLPDCSGHGTFD 1022
             C HP    CS +  C+ G+     C C KGW G    C  +D+  L     C       
Sbjct: 864  PCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDVRGGCHTDALCS 923

Query: 1023 V---DTQTCSCHAKWSGE--DCSK-EVCSL-ECGPHG----RCVG---ESCSCAAGWSGE 1068
                    C+C   ++G+   CS  + C     G HG    R VG     C+C  G+ G+
Sbjct: 924  YVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGD 983



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 50/159 (31%), Positives = 61/159 (38%), Gaps = 30/159 (18%)

Query: 992  CKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSLEC 1048
            C KG+ G DC T           C G G      Q    C C   + G  C   +CS   
Sbjct: 720  CCKGFFGPDC-TQCPGGFS--NPCYGKGNCSDGIQGNGACLCFPDYKGIAC--HICS-NP 773

Query: 1049 GPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE---- 1104
              HG    E C C  G         LCD R    G C+ GT  C  G++GR C       
Sbjct: 774  NKHGEQCQEDCGCVHG---------LCDNRPGSGGVCQQGT--CAPGFSGRFCNESMGDC 822

Query: 1105 ---GCPRSCAGHGQCRVDNDGRWECKCFDGW--DGPDCT 1138
               G  + C  H +C V  +G   C+C DG+  DG  CT
Sbjct: 823  GPTGLAQHCHLHARC-VSQEGVARCRCLDGFEGDGFSCT 860



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 61/220 (27%), Positives = 82/220 (37%), Gaps = 42/220 (19%)

Query: 885  KGECLMGH----CQCQPGFGGDDCS-KSVCPVLCSQRGEYINGECQCNPGWKGKECSL-- 937
            K  C  GH    CQ  PG     CS + VC       G   +G+C C  G+ G  C L  
Sbjct: 1956 KPSCCPGHYGSECQACPGGPSSPCSDRGVC-----MDGMSGSGQCLCRSGFAGTACELCA 2010

Query: 938  ---RHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEIDCP-----HPTCSGHGF 984
                   C+   C  HG C      +G C C  G+ G  C E+         P C+    
Sbjct: 2011 PGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC-EVQLELQPVCTPPCAPEAV 2069

Query: 985  CIEG-TCVCKKGWKGADCGTMDKDALQ-CLPDCSGHGT-FDVDTQ-TCSCHAKWSGE--D 1038
            C  G +C C  G++G        D  Q     CS H     V T  TC+C   + G+   
Sbjct: 2070 CRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWS 2129

Query: 1039 C-SKEVCS----LECGPHGRCVG-----ESCSCAAGWSGE 1068
            C ++  C+      C  H  C+        C C AG+ G+
Sbjct: 2130 CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGD 2169



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 63/237 (26%), Positives = 89/237 (37%), Gaps = 45/237 (18%)

Query: 933  KECSLRHDECEV----PDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP---HPTCSGHGFC 985
            KEC   HD   +      C  + +    +  C +G+ G  C +  CP      C G G C
Sbjct: 689  KECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKGFFGPDCTQ--CPGGFSNPCYGKGNC 746

Query: 986  IEG-----TCVCKKGWKGADC---GTMDKDALQCLPDCSG-HGTFDVDTQTCSCHAKWSG 1036
             +G      C+C   +KG  C      +K   QC  DC   HG  D        +   SG
Sbjct: 747  SDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCD--------NRPGSG 798

Query: 1037 EDCSKEVCSLECGPHGRCVGESCS-CAAGWSGEFCSVRLCDARC-AEHGQCKNGTCLCVS 1094
              C +  C+   G  GR   ES   C      + C +    ARC ++ G  +   C C+ 
Sbjct: 799  GVCQQGTCAP--GFSGRFCNESMGDCGPTGLAQHCHLH---ARCVSQEGVAR---CRCLD 850

Query: 1095 GWNGR--HCTLEG-CPR----SCAGHGQCRVDNDGRWECKCFDGW--DGPDCTTLKE 1142
            G+ G    CT    C       C+ + +C   + G   C C  GW  DG  C  + E
Sbjct: 851  GFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDE 907



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/164 (26%), Positives = 56/164 (34%), Gaps = 27/164 (16%)

Query: 876  HNCPNG----CSGKGECL-----MGHCQCQPGFGGDDCSKSV--------CPVLCS---- 914
            H CP G    C+G G CL      G C CQ  F G  C +          C  +CS    
Sbjct: 110  HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG 169

Query: 915  --QRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHC--VNGKCSCVRGYKGKFCG 970
                G   +G C C  G+ G  C      C+   C  +  C      C C+ GY  +   
Sbjct: 170  VCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQ-GS 228

Query: 971  EIDCPHPTCSGHGFCIEGTCVCKKGWKGADC-GTMDKDALQCLP 1013
            E   P+P        +    V  KG     C      D + CLP
Sbjct: 229  ECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLP 272



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 35/108 (32%), Positives = 43/108 (39%), Gaps = 21/108 (19%)

Query: 1049 GPHGRCVGESC--SCAAGWSGEFCSVRLC----DARCAEHGQCKNGT-----CLCVSGWN 1097
            G H  CV  +   SC  G  G  C    C     + C++ G C +G      CLC SG+ 
Sbjct: 1945 GCHRNCVTTTWKPSCCPGHYGSECQA--CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFA 2002

Query: 1098 GRHCTL-------EGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G  C L         C    C  HG+C     G   C C +GW GP C
Sbjct: 2003 GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC 2050



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 43/164 (26%), Positives = 63/164 (38%), Gaps = 18/164 (10%)

Query: 1019 GTFDVDTQTC-SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDA 1077
            G   V +  C   HA+   E C        C   G  + ++   +  +   F   R C  
Sbjct: 1251 GVLTVGSSRCLHSHAEALREKCVNCTRRFRC-TQGFQLQDTPRKSCVYRSGFSFSRGCSY 1309

Query: 1078 RCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS----CAGHGQCRVDNDGRWECKCFDGWD 1133
             CA+  Q  +    C  G+ G  C  E CP      C+GHGQC+    G  EC C +G+ 
Sbjct: 1310 TCAKKIQVPD----CCPGFFGTLC--EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFH 1363

Query: 1134 GPDCTTLKEQICDDSRDNDK-DGLVDCEDPECCQSPACKSSQLC 1176
            G  C     ++C+  R      G+ DC    C +      S +C
Sbjct: 1364 GTAC-----EVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVC 1402



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 40/127 (31%), Positives = 52/127 (40%), Gaps = 17/127 (13%)

Query: 1024 DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHG 1083
            DT   SC  + SG   S+  CS  C    + V + C    G   E C   L    C+ HG
Sbjct: 1289 DTPRKSCVYR-SGFSFSRG-CSYTCAKKIQ-VPDCCPGFFGTLCEPCPGGLGGV-CSGHG 1344

Query: 1084 QCKN-----GTCLCVSGWNGRHCTLEGCPR---SCAG-----HGQCRVDNDGRWECKCFD 1130
            QC++     G C C  G++G  C +    R   +C G     HG C+    G   C C  
Sbjct: 1345 QCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNV 1404

Query: 1131 GWDGPDC 1137
            GW G  C
Sbjct: 1405 GWQGLRC 1411



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 32/125 (25%), Positives = 40/125 (32%), Gaps = 11/125 (8%)

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR-HCTLEGCPRSCAGH 1113
            + + C       G   S+  C  +C +  Q     C C   W  R H    G    C GH
Sbjct: 67   ITQDCRYEVQLGGSMVSMSGCRRKCRK--QVVQKAC-CPGYWGSRCHECPGGAETPCNGH 123

Query: 1114 GQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSR--DNDKDGLVDCEDPECCQSPACK 1171
            G C    D    C C + + G  C     Q C D      D   +  C    C   P   
Sbjct: 124  GTCLDGMDRNGTCVCQENFRGSAC-----QECQDPNRFGPDCQSVCSCVHGVCNHGPRGD 178

Query: 1172 SSQLC 1176
             S LC
Sbjct: 179  GSCLC 183


>AL080120-1|CAB45719.1|  184|Homo sapiens hypothetical protein
            protein.
          Length = 184

 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 55/176 (31%), Positives = 85/176 (48%), Gaps = 6/176 (3%)

Query: 2783 GANSVVEDVITTVFNNSYFLDVHFSIHDQDVFYFVK----DNSLKIRDDMEELRRLSGKF 2838
            GAN     V   + +  Y  ++HF+I   D  YFVK    +  L I       R L    
Sbjct: 1    GANEDGRRVAAILDHAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLSGGRRTLENGV 60

Query: 2839 NVSQDETND--QGLEVRVHAVGKGSAQAVIVLRYGVDPAQERIKLLKHAHKRAATRAWER 2896
            NV+  + N    G   R   +        +  RYG    +E+ ++L+ A +RA  +AW R
Sbjct: 61   NVTVSQINTVLNGRTRRYTDIQLQYGALCLNTRYGTTLDEEKARVLELARQRAVRQAWAR 120

Query: 2897 EKALVAAGWEGRGSWTEEEKEELISHGIVDGWAARDVHSISKYPQLADDPANIVFV 2952
            E+  +  G EG  +WTE EK++++S G V G+    V S+ +YP+L+D   NI F+
Sbjct: 121  EQQRLREGEEGLRAWTEGEKQQVLSTGRVQGYDGFFVISVEQYPELSDSANNIHFM 176


>AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein.
          Length = 2570

 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 69/231 (29%), Positives = 101/231 (43%), Gaps = 50/231 (21%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCG--EIDCPHPTCSG-----HGFCIEG-----T 989
            C+GHG C +     G+C C  G+ G  C   E+    P C+G     HG C EG     +
Sbjct: 1340 CSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGS 1399

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDT---QTCSCHAKWSGED--CSK-EV 1043
            CVC  GW+G  C        QC   C  +     D+    TC+C A +SG    CS+ + 
Sbjct: 1400 CVCNVGWQGLRCDQKITSP-QCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDP 1458

Query: 1044 CSLE---CGPHGRCV----GE-SCSCAAGW--SGEFCS-VRLC---DARCAEHGQC---- 1085
            C+     C PH  C     G+ +C+C  G+   GE C  +  C      C  H +C    
Sbjct: 1459 CAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTG 1518

Query: 1086 -KNGTCLCVSGWNG---RHCTL-EGCPRS---CAGHGQCRVDNDGRWECKC 1128
             +  +C C  G++G   R C L + C ++   C+ +  C+   DG+  C C
Sbjct: 1519 PQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 65/222 (29%), Positives = 90/222 (40%), Gaps = 46/222 (20%)

Query: 960  CVRGYKGKFCGEIDCPHP---TCSGHGFCIE-----GTCVCKKGWKGADCGTMDKDALQC 1011
            C  G+ G  C    CP      CSGHG C +     G C C +G+ G  C   +      
Sbjct: 1320 CCPGFFGTLCEP--CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYG- 1376

Query: 1012 LPDCSG-----HGTFDVDTQ---TCSCHAKWSGEDCSKEV----CSLECGPHGRCVGES- 1058
             P+C+G     HG      Q   +C C+  W G  C +++    C  +C P+  CV +S 
Sbjct: 1377 -PNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSA 1435

Query: 1059 ----CSCAAGWSGE--FCS-VRLC---DARCAEHGQCK-----NGTCLCVSGW--NGRHC 1101
                C+CAAG+SG   FCS V  C      C+ H  C        TC C  G+  +G  C
Sbjct: 1436 GASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELC 1495

Query: 1102 -TLEGC---PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
              +  C      C  H +C      +  C C +G+ G    T
Sbjct: 1496 QEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT 1537



 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 63/207 (30%), Positives = 91/207 (43%), Gaps = 43/207 (20%)

Query: 959  SCVRGYKGKFCGEIDCP---HPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQ 1010
            +C  GY G  C E  CP      C+GHG C++G     TCVC++ ++G+ C    +D  +
Sbjct: 99   ACCPGYWGSRCHE--CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQEC-QDPNR 155

Query: 1011 CLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFC 1070
              PDC            CSC            VC+   GP G     SC C AG++G  C
Sbjct: 156  FGPDCQS---------VCSC---------VHGVCNH--GPRG---DGSCLCFAGYTGPHC 192

Query: 1071 SVRL--C-DARCAEHGQC--KNGTCLCVSGWN--GRHCTLEG-C-PRSCAGHGQCRVDND 1121
               L  C + RC ++ QC  +  +C C+ G+   G  C     C P  C+   QC V   
Sbjct: 193  DQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPK 252

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDDS 1148
            G+ +C C + + G     L +  C D+
Sbjct: 253  GQAQCHCPENYHGDGMVCLPKDPCTDN 279



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 78/266 (29%), Positives = 101/266 (37%), Gaps = 66/266 (24%)

Query: 878  CPNG----CSGKGECL-----MGHCQCQPGFGGDDCSKSV-------CPVLCS------Q 915
            CP G    CSG G+C       G C C  GF G  C           C  +C       Q
Sbjct: 1332 CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQ 1391

Query: 916  RGEYINGECQCNPGWKGKECSLRHDECEVP-DCNGHGHCVN-----GKCSCVRGYKGK-- 967
             G   +G C CN GW+G  C  +    + P  C+ + +CV        C+C  GY G   
Sbjct: 1392 EGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGI 1451

Query: 968  FCGEID-CP--HPTCSGHGFCI-----EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHG 1019
            FC E+D C   H  CS H  C      + TC C+ G+ G   G + ++   CL     HG
Sbjct: 1452 FCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGD--GELCQEINSCL---IHHG 1506

Query: 1020 TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE-FCSVRLCDAR 1078
                    C  HA              EC P G     SCSC  G+SG+   +  L D  
Sbjct: 1507 -------GCHIHA--------------ECIPTGP-QQVSCSCREGYSGDGIRTCELLDPC 1544

Query: 1079 CAEHGQCKNGTCLCVSGWNGRHCTLE 1104
               +G C        +G   R CT +
Sbjct: 1545 SKNNGGCSPYATCKSTGDGQRTCTCD 1570



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 85/313 (27%), Positives = 122/313 (38%), Gaps = 65/313 (20%)

Query: 878  CPNGCSGK-GECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            CP+G   +  + +   C+ +   GG   S S C   C  R + +   C C PG+ G  C 
Sbjct: 55   CPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKC--RKQVVQKAC-C-PGYWGSRCH 110

Query: 937  LRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGKFCGEIDCPH---PTCSG-----HG 983
                  E P CNGHG C+     NG C C   ++G  C E   P+   P C       HG
Sbjct: 111  ECPGGAETP-CNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG 169

Query: 984  FCI-----EGTCVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFDVDTQTCSCHAKWS-- 1035
             C      +G+C+C  G+ G  C   D++   C    C  +     +  +C C   ++  
Sbjct: 170  VCNHGPRGDGSCLCFAGYTGPHC---DQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQ 226

Query: 1036 GEDCSK------EVCSL--ECG--PHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH-GQ 1084
            G +C          CSL  +C   P G+     C C   + G+   V L    C ++ G 
Sbjct: 227  GSECRAPNPCWPSPCSLLAQCSVSPKGQA---QCHCPENYHGDGM-VCLPKDPCTDNLGG 282

Query: 1085 CKNGTCLCVSGWNGR-HCTLE------------GC-----PRSCAGHGQCRVDNDGRWEC 1126
            C + + LCV    G+  CT              GC     P SC     C+V  DG+  C
Sbjct: 283  CPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSC 342

Query: 1127 KCFDG--WDGPDC 1137
             C +    DG  C
Sbjct: 343  VCRESEVGDGRAC 355



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 63/211 (29%), Positives = 86/211 (40%), Gaps = 31/211 (14%)

Query: 878  CPNGCSGKGECLMGH------CQ-CQPGFGGDDCSKSVCPV--LCSQRGEYINGECQCNP 928
            C +G SG G+CL         C+ C PG  G  C    C V   C + G   +G C C+ 
Sbjct: 1985 CMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDE-GLGGSGSCFCDE 2043

Query: 929  GWKGKECSLRHDECEV--PDCNGHGHCVNG-KCSCVRGYK--GKFCGEID-CP--HPTCS 980
            GW G  C ++ +   V  P C     C  G  C C  GY+  G+ C   D C   H  CS
Sbjct: 2044 GWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCS 2103

Query: 981  GHGFCIE----GTCVCKKGWKGA--DCGTMDKDALQCLPDCSGHG---TFDVDTQTCSCH 1031
             H  C +     TC C   ++G    C   +         CS H    +  ++T+ C CH
Sbjct: 2104 EHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECH 2163

Query: 1032 AKWSGEDCSKEVCSLECGPH-GRCVGESCSC 1061
            A + G+      C  E  P   RC+G+   C
Sbjct: 2164 AGYVGDGLQ---CLEESEPPVDRCLGQPPPC 2191



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 83/272 (30%), Positives = 110/272 (40%), Gaps = 59/272 (21%)

Query: 895  CQPGFGGDDCSKSVCPV----LCSQRGEYI-----NGECQCNPGWKGKECSL-----RHD 940
            C  GF G DC++  CP      C  +G        NG C C P +KG  C +     +H 
Sbjct: 720  CCKGFFGPDCTQ--CPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHG 777

Query: 941  ECEVPDCN-GHGHCVN-----GKC---SCVRGYKGKFCGEI--DCPHPT-----CSGHGF 984
            E    DC   HG C N     G C   +C  G+ G+FC E   DC  PT     C  H  
Sbjct: 778  EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC-GPTGLAQHCHLHAR 836

Query: 985  CI--EGT--CVCKKGWK--GADCGTMDKDALQCLPDCSGHGTF---DVDTQTCSCHAKWS 1035
            C+  EG   C C  G++  G  C   +  +      CS +       + T  C+CH  WS
Sbjct: 837  CVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWS 896

Query: 1036 GED--C-SKEVCSLE----CGPHGRC----VGES-CSCAAGWSGEFCSVRLCDARCAEHG 1083
            G+   C + + C L+    C     C     G+S C+C  G++G+       D   A +G
Sbjct: 897  GDGRVCVAIDECELDVGGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNG 956

Query: 1084 QCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
             C    TC  V G   R CT   CP    G G
Sbjct: 957  GCHGLATCRAVGG-GQRVCT---CPPGFGGDG 984



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 62/206 (30%), Positives = 85/206 (41%), Gaps = 38/206 (18%)

Query: 948  NGHGHCVNGKC-SCVRGYKGKFCGEI-DCPHPTC---SGHGFCIEGTCVCKKGWKGADC- 1001
            + H   +  KC +C R ++     ++ D P  +C   SG  F    +  C K  +  DC 
Sbjct: 1262 HSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCC 1321

Query: 1002 ----GTMDKDALQCLPD-CSGHGTFD---VDTQTCSCHAKWSGEDCSKEVCSLECGPHG- 1052
                GT+ +     L   CSGHG      + +  C CH  + G  C  EVC L  G +G 
Sbjct: 1322 PGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTAC--EVCEL--GRYGP 1377

Query: 1053 RCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHC----TLEGCPR 1108
             C G  C CA G         LC     + G   +G+C+C  GW G  C    T   CPR
Sbjct: 1378 NCTGV-CDCAHG---------LC-----QEGLQGDGSCVCNVGWQGLRCDQKITSPQCPR 1422

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGWDG 1134
             C  +  C  D+ G   C C  G+ G
Sbjct: 1423 KCDPNANCVQDSAGASTCACAAGYSG 1448



 Score = 61.3 bits (142), Expect = 5e-08
 Identities = 66/239 (27%), Positives = 86/239 (35%), Gaps = 43/239 (17%)

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNG-----KCSCVRGYKGKFC-----GEID-- 973
            C PG  G EC         P C+  G C++G     +C C  G+ G  C     G     
Sbjct: 1959 CCPGHYGSECQACPGGPSSP-CSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPH 2017

Query: 974  CPHPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTC 1028
            C    C+ HG C EG     +C C +GW G  C    +    C P C+            
Sbjct: 2018 CQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAV-------- 2069

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C A   G  C    CSL     GR    +  C  G  G  CS     A C++ G     
Sbjct: 2070 -CRA---GNSCE---CSLGYEGDGRVCTVADLCQDGHGG--CSEH---ANCSQVGTMVTC 2117

Query: 1089 TCLC---VSGWN--GRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
            TCL      GW+   R+   +G    C+ H  C         C+C  G+ G     L+E
Sbjct: 2118 TCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEE 2176



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 50/159 (31%), Positives = 61/159 (38%), Gaps = 30/159 (18%)

Query: 992  CKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSLEC 1048
            C KG+ G DC T           C G G      Q    C C   + G  C   +CS   
Sbjct: 720  CCKGFFGPDC-TQCPGGFS--NPCYGKGNCSDGIQGNGACLCFPDYKGIAC--HICS-NP 773

Query: 1049 GPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE---- 1104
              HG    E C C  G         LCD R    G C+ GT  C  G++GR C       
Sbjct: 774  NKHGEQCQEDCGCVHG---------LCDNRPGSGGVCQQGT--CAPGFSGRFCNESMGDC 822

Query: 1105 ---GCPRSCAGHGQCRVDNDGRWECKCFDGW--DGPDCT 1138
               G  + C  H +C V  +G   C+C DG+  DG  CT
Sbjct: 823  GPTGLAQHCHLHARC-VSQEGVARCRCLDGFEGDGFSCT 860



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 61/220 (27%), Positives = 82/220 (37%), Gaps = 42/220 (19%)

Query: 885  KGECLMGH----CQCQPGFGGDDCS-KSVCPVLCSQRGEYINGECQCNPGWKGKECSL-- 937
            K  C  GH    CQ  PG     CS + VC       G   +G+C C  G+ G  C L  
Sbjct: 1956 KPSCCPGHYGSECQACPGGPSSPCSDRGVC-----MDGMSGSGQCLCRSGFAGTACELCA 2010

Query: 938  ---RHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEIDCP-----HPTCSGHGF 984
                   C+   C  HG C      +G C C  G+ G  C E+         P C+    
Sbjct: 2011 PGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC-EVQLELQPVCTPPCAPEAV 2069

Query: 985  CIEG-TCVCKKGWKGADCGTMDKDALQ-CLPDCSGHGT-FDVDTQ-TCSCHAKWSGE--D 1038
            C  G +C C  G++G        D  Q     CS H     V T  TC+C   + G+   
Sbjct: 2070 CRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWS 2129

Query: 1039 C-SKEVCS----LECGPHGRCVG-----ESCSCAAGWSGE 1068
            C ++  C+      C  H  C+        C C AG+ G+
Sbjct: 2130 CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGD 2169



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 63/237 (26%), Positives = 89/237 (37%), Gaps = 45/237 (18%)

Query: 933  KECSLRHDECEV----PDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP---HPTCSGHGFC 985
            KEC   HD   +      C  + +    +  C +G+ G  C +  CP      C G G C
Sbjct: 689  KECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKGFFGPDCTQ--CPGGFSNPCYGKGNC 746

Query: 986  IEG-----TCVCKKGWKGADC---GTMDKDALQCLPDCSG-HGTFDVDTQTCSCHAKWSG 1036
             +G      C+C   +KG  C      +K   QC  DC   HG  D        +   SG
Sbjct: 747  SDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCD--------NRPGSG 798

Query: 1037 EDCSKEVCSLECGPHGRCVGESCS-CAAGWSGEFCSVRLCDARC-AEHGQCKNGTCLCVS 1094
              C +  C+   G  GR   ES   C      + C +    ARC ++ G  +   C C+ 
Sbjct: 799  GVCQQGTCAP--GFSGRFCNESMGDCGPTGLAQHCHLH---ARCVSQEGVAR---CRCLD 850

Query: 1095 GWNGR--HCTLEG-CPR----SCAGHGQCRVDNDGRWECKCFDGW--DGPDCTTLKE 1142
            G+ G    CT    C       C+ + +C   + G   C C  GW  DG  C  + E
Sbjct: 851  GFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDE 907



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/164 (26%), Positives = 56/164 (34%), Gaps = 27/164 (16%)

Query: 876  HNCPNG----CSGKGECL-----MGHCQCQPGFGGDDCSKSV--------CPVLCS---- 914
            H CP G    C+G G CL      G C CQ  F G  C +          C  +CS    
Sbjct: 110  HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG 169

Query: 915  --QRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHC--VNGKCSCVRGYKGKFCG 970
                G   +G C C  G+ G  C      C+   C  +  C      C C+ GY  +   
Sbjct: 170  VCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQ-GS 228

Query: 971  EIDCPHPTCSGHGFCIEGTCVCKKGWKGADC-GTMDKDALQCLP 1013
            E   P+P        +    V  KG     C      D + CLP
Sbjct: 229  ECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLP 272



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 35/108 (32%), Positives = 43/108 (39%), Gaps = 21/108 (19%)

Query: 1049 GPHGRCVGESC--SCAAGWSGEFCSVRLC----DARCAEHGQCKNGT-----CLCVSGWN 1097
            G H  CV  +   SC  G  G  C    C     + C++ G C +G      CLC SG+ 
Sbjct: 1945 GCHRNCVTTTWKPSCCPGHYGSECQA--CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFA 2002

Query: 1098 GRHCTL-------EGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G  C L         C    C  HG+C     G   C C +GW GP C
Sbjct: 2003 GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC 2050



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 43/164 (26%), Positives = 63/164 (38%), Gaps = 18/164 (10%)

Query: 1019 GTFDVDTQTC-SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDA 1077
            G   V +  C   HA+   E C        C   G  + ++   +  +   F   R C  
Sbjct: 1251 GVLTVGSSRCLHSHAEALREKCVNCTRRFRC-TQGFQLQDTPRKSCVYRSGFSFSRGCSY 1309

Query: 1078 RCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS----CAGHGQCRVDNDGRWECKCFDGWD 1133
             CA+  Q  +    C  G+ G  C  E CP      C+GHGQC+    G  EC C +G+ 
Sbjct: 1310 TCAKKIQVPD----CCPGFFGTLC--EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFH 1363

Query: 1134 GPDCTTLKEQICDDSRDNDK-DGLVDCEDPECCQSPACKSSQLC 1176
            G  C     ++C+  R      G+ DC    C +      S +C
Sbjct: 1364 GTAC-----EVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVC 1402



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 40/127 (31%), Positives = 52/127 (40%), Gaps = 17/127 (13%)

Query: 1024 DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHG 1083
            DT   SC  + SG   S+  CS  C    + V + C    G   E C   L    C+ HG
Sbjct: 1289 DTPRKSCVYR-SGFSFSRG-CSYTCAKKIQ-VPDCCPGFFGTLCEPCPGGLGGV-CSGHG 1344

Query: 1084 QCKN-----GTCLCVSGWNGRHCTLEGCPR---SCAG-----HGQCRVDNDGRWECKCFD 1130
            QC++     G C C  G++G  C +    R   +C G     HG C+    G   C C  
Sbjct: 1345 QCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNV 1404

Query: 1131 GWDGPDC 1137
            GW G  C
Sbjct: 1405 GWQGLRC 1411



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 32/125 (25%), Positives = 40/125 (32%), Gaps = 11/125 (8%)

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR-HCTLEGCPRSCAGH 1113
            + + C       G   S+  C  +C +  Q     C C   W  R H    G    C GH
Sbjct: 67   ITQDCRYEVQLGGSMVSMSGCRRKCRK--QVVQKAC-CPGYWGSRCHECPGGAETPCNGH 123

Query: 1114 GQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSR--DNDKDGLVDCEDPECCQSPACK 1171
            G C    D    C C + + G  C     Q C D      D   +  C    C   P   
Sbjct: 124  GTCLDGMDRNGTCVCQENFRGSAC-----QECQDPNRFGPDCQSVCSCVHGVCNHGPRGD 178

Query: 1172 SSQLC 1176
             S LC
Sbjct: 179  GSCLC 183


>AB209707-1|BAD92944.1| 1720|Homo sapiens low density
            lipoprotein-related protein 1B variant protein.
          Length = 1720

 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 59/207 (28%), Positives = 80/207 (38%), Gaps = 24/207 (11%)

Query: 989  TCVCKKGWKGADCGTMDKDAL---QCLPDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKE 1042
            TCVC +G K    GT + D+L    C   C   G   ++ +    C C   +SGE C   
Sbjct: 1314 TCVCPEG-KYLINGTCNDDSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGERCEVN 1372

Query: 1043 VCSLECGPHGRCVGE-----SCSCAAGWSGEFCSVRLCDARCAEHGQC-----KNGTCLC 1092
             CS  C   G C+       +CSCA G++G  C   +C+  C   G C         C C
Sbjct: 1373 HCSNYCQNGGTCLPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQPYCHC 1432

Query: 1093 VSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSR--- 1149
               + G  C    C   C     C + +DG  EC C   ++GP C   K   C       
Sbjct: 1433 QPEYTGDRCQYYVCHHYCVNSESCTIGDDGSVECVCPTRYEGPKCEVDKCVRCHGGHCII 1492

Query: 1150 DNDKDGLVDCEDPECCQSPACKSSQLC 1176
            + D + +  C    C       S QLC
Sbjct: 1493 NKDSEDIF-C---NCTNGKIASSCQLC 1515



 Score = 68.1 bits (159), Expect = 5e-10
 Identities = 59/189 (31%), Positives = 75/189 (39%), Gaps = 29/189 (15%)

Query: 873  EMTHNCPNGCSGKGECL---MGH--CQCQPGFGGDDCSKSVCPVLCSQRGEYI-----NG 922
            E+ H C N C   G CL   +G   C C  GF G +C K+VC   C   G  I       
Sbjct: 1370 EVNH-CSNYCQNGGTCLPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCIVTAGNQP 1428

Query: 923  ECQCNPGWKGKECS--LRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCS 980
             C C P + G  C   + H  C   +    G   + +C C   Y+G  C E+D     C 
Sbjct: 1429 YCHCQPEYTGDRCQYYVCHHYCVNSESCTIGDDGSVECVCPTRYEGPKC-EVD----KCV 1483

Query: 981  GHGFCIEGTCVCKKGWKGADCG-TMDKDALQC-LPD--CSGHGTFDVDTQT----CSCHA 1032
                C  G C+  K  +   C  T  K A  C L D  C   GT  +D +T    C C  
Sbjct: 1484 R---CHGGHCIINKDSEDIFCNCTNGKIASSCQLCDGYCYNGGTCQLDPETNVPVCLCST 1540

Query: 1033 KWSGEDCSK 1041
             WSG  C +
Sbjct: 1541 NWSGTQCER 1549



 Score = 65.7 bits (153), Expect = 2e-09
 Identities = 59/218 (27%), Positives = 80/218 (36%), Gaps = 33/218 (15%)

Query: 909  CPVLCSQRGEYINGE-----CQCNPGWKGKECSLRHDECEVPDCNGHGHC---VNGK--C 958
            C + C   G  I  E     C C P + G+ C + H  C    C   G C   V G+  C
Sbjct: 1338 CKLTCENGGRCILNEKGDLRCHCWPSYSGERCEVNH--CS-NYCQNGGTCLPSVLGRPTC 1394

Query: 959  SCVRGYKGKFCGEIDCPHPTCSGHGFCI-----EGTCVCKKGWKGADCGTMDKDALQCLP 1013
            SC  G+ G  CG+  C    C   G CI     +  C C+  + G  C            
Sbjct: 1395 SCALGFTGPNCGKTVC-EDFCQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVCHHYCVNS 1453

Query: 1014 DCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES----CSCAAGWSGEF 1069
            +    G  D  +  C C  ++ G  C  + C    G H     +S    C+C  G     
Sbjct: 1454 ESCTIG--DDGSVECVCPTRYEGPKCEVDKCVRCHGGHCIINKDSEDIFCNCTNGKIASS 1511

Query: 1070 CSVRLCDARCAEHGQCKNG------TCLCVSGWNGRHC 1101
            C  +LCD  C   G C+         CLC + W+G  C
Sbjct: 1512 C--QLCDGYCYNGGTCQLDPETNVPVCLCSTNWSGTQC 1547



 Score = 39.5 bits (88), Expect = 0.18
 Identities = 72/281 (25%), Positives = 96/281 (34%), Gaps = 52/281 (18%)

Query: 909  CPVLCSQRGEYINGECQCN-PGW--KGK-ECSLRHDE--CEVPDC-NGHGHCV-NGKCSC 960
            CP    Q G +  G   C  P +   G+ +C    DE  C+   C +G   C  N KC  
Sbjct: 473  CPEFRCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIP 532

Query: 961  V--RGYKGKFCG----EIDCPHPTCSGHGFCIEGTCVC-KKGW---KGADCGTMDKDALQ 1010
            V  R      CG    E DCP  +CS   F  + T  C  K W   +  DC     +A  
Sbjct: 533  VNLRCNGQDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEA-N 591

Query: 1011 CLPDCSGHGTFDVDTQTC-----------SCHAKWSGEDCSKEVCSLE---CGPHGRCVG 1056
            C     G   F      C            C      E+C  + C+L+   C  +G CV 
Sbjct: 592  CDKKTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKDFLCA-NGDCVS 650

Query: 1057 ESCSCAAGWS-GEFCSVRLCDARCA-EHGQCKNGTCL-----------CVSGWNGRHC-- 1101
                C   +   +    R C+  C+ +  +C NG C+           C  G + + C  
Sbjct: 651  SRFWCDGDFDCADGSDERNCETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEP 710

Query: 1102 ---TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
               T       CA  G          E  C DG D  DC T
Sbjct: 711  ASPTCSSREYICASDGCISASLKCNGEYDCADGSDEMDCVT 751


>AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein.
          Length = 2570

 Score = 81.4 bits (192), Expect = 5e-14
 Identities = 69/231 (29%), Positives = 101/231 (43%), Gaps = 50/231 (21%)

Query: 947  CNGHGHCVN-----GKCSCVRGYKGKFCG--EIDCPHPTCSG-----HGFCIEG-----T 989
            C+GHG C +     G+C C  G+ G  C   E+    P C+G     HG C EG     +
Sbjct: 1340 CSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGS 1399

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDT---QTCSCHAKWSGED--CSK-EV 1043
            CVC  GW+G  C        QC   C  +     D+    TC+C A +SG    CS+ + 
Sbjct: 1400 CVCNVGWQGLRCDQKITSP-QCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDP 1458

Query: 1044 CSLE---CGPHGRCV----GE-SCSCAAGW--SGEFCS-VRLC---DARCAEHGQC---- 1085
            C+     C PH  C     G+ +C+C  G+   GE C  +  C      C  H +C    
Sbjct: 1459 CAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGGCHIHAECIPTG 1518

Query: 1086 -KNGTCLCVSGWNG---RHCTL-EGCPRS---CAGHGQCRVDNDGRWECKC 1128
             +  +C C  G++G   R C L + C ++   C+ +  C+   DG+  C C
Sbjct: 1519 PQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTC 1569



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 65/222 (29%), Positives = 90/222 (40%), Gaps = 46/222 (20%)

Query: 960  CVRGYKGKFCGEIDCPHP---TCSGHGFCIE-----GTCVCKKGWKGADCGTMDKDALQC 1011
            C  G+ G  C    CP      CSGHG C +     G C C +G+ G  C   +      
Sbjct: 1320 CCPGFFGTLCEP--CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYG- 1376

Query: 1012 LPDCSG-----HGTFDVDTQ---TCSCHAKWSGEDCSKEV----CSLECGPHGRCVGES- 1058
             P+C+G     HG      Q   +C C+  W G  C +++    C  +C P+  CV +S 
Sbjct: 1377 -PNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSA 1435

Query: 1059 ----CSCAAGWSGE--FCS-VRLC---DARCAEHGQCK-----NGTCLCVSGW--NGRHC 1101
                C+CAAG+SG   FCS V  C      C+ H  C        TC C  G+  +G  C
Sbjct: 1436 GASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELC 1495

Query: 1102 -TLEGC---PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
              +  C      C  H +C      +  C C +G+ G    T
Sbjct: 1496 QEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT 1537



 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 63/207 (30%), Positives = 91/207 (43%), Gaps = 43/207 (20%)

Query: 959  SCVRGYKGKFCGEIDCP---HPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQ 1010
            +C  GY G  C E  CP      C+GHG C++G     TCVC++ ++G+ C    +D  +
Sbjct: 99   ACCPGYWGSRCHE--CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQEC-QDPNR 155

Query: 1011 CLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFC 1070
              PDC            CSC            VC+   GP G     SC C AG++G  C
Sbjct: 156  FGPDCQS---------VCSC---------VHGVCNH--GPRG---DGSCLCFAGYTGPHC 192

Query: 1071 SVRL--C-DARCAEHGQC--KNGTCLCVSGWN--GRHCTLEG-C-PRSCAGHGQCRVDND 1121
               L  C + RC ++ QC  +  +C C+ G+   G  C     C P  C+   QC V   
Sbjct: 193  DQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPK 252

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDDS 1148
            G+ +C C + + G     L +  C D+
Sbjct: 253  GQAQCHCPENYHGDGMVCLPKDPCTDN 279



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 78/266 (29%), Positives = 101/266 (37%), Gaps = 66/266 (24%)

Query: 878  CPNG----CSGKGECL-----MGHCQCQPGFGGDDCSKSV-------CPVLCS------Q 915
            CP G    CSG G+C       G C C  GF G  C           C  +C       Q
Sbjct: 1332 CPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQ 1391

Query: 916  RGEYINGECQCNPGWKGKECSLRHDECEVP-DCNGHGHCVN-----GKCSCVRGYKGK-- 967
             G   +G C CN GW+G  C  +    + P  C+ + +CV        C+C  GY G   
Sbjct: 1392 EGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGI 1451

Query: 968  FCGEID-CP--HPTCSGHGFCI-----EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHG 1019
            FC E+D C   H  CS H  C      + TC C+ G+ G   G + ++   CL     HG
Sbjct: 1452 FCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGD--GELCQEINSCL---IHHG 1506

Query: 1020 TFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE-FCSVRLCDAR 1078
                    C  HA              EC P G     SCSC  G+SG+   +  L D  
Sbjct: 1507 -------GCHIHA--------------ECIPTGP-QQVSCSCREGYSGDGIRTCELLDPC 1544

Query: 1079 CAEHGQCKNGTCLCVSGWNGRHCTLE 1104
               +G C        +G   R CT +
Sbjct: 1545 SKNNGGCSPYATCKSTGDGQRTCTCD 1570



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 85/313 (27%), Positives = 122/313 (38%), Gaps = 65/313 (20%)

Query: 878  CPNGCSGK-GECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            CP+G   +  + +   C+ +   GG   S S C   C  R + +   C C PG+ G  C 
Sbjct: 55   CPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKC--RKQVVQKAC-C-PGYWGSRCH 110

Query: 937  LRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGKFCGEIDCPH---PTCSG-----HG 983
                  E P CNGHG C+     NG C C   ++G  C E   P+   P C       HG
Sbjct: 111  ECPGGAETP-CNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG 169

Query: 984  FCI-----EGTCVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFDVDTQTCSCHAKWS-- 1035
             C      +G+C+C  G+ G  C   D++   C    C  +     +  +C C   ++  
Sbjct: 170  VCNHGPRGDGSCLCFAGYTGPHC---DQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQ 226

Query: 1036 GEDCSK------EVCSL--ECG--PHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH-GQ 1084
            G +C          CSL  +C   P G+     C C   + G+   V L    C ++ G 
Sbjct: 227  GSECRAPNPCWPSPCSLLAQCSVSPKGQA---QCHCPENYHGDGM-VCLPKDPCTDNLGG 282

Query: 1085 CKNGTCLCVSGWNGR-HCTLE------------GC-----PRSCAGHGQCRVDNDGRWEC 1126
            C + + LCV    G+  CT              GC     P SC     C+V  DG+  C
Sbjct: 283  CPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSC 342

Query: 1127 KCFDG--WDGPDC 1137
             C +    DG  C
Sbjct: 343  VCRESEVGDGRAC 355



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 63/211 (29%), Positives = 86/211 (40%), Gaps = 31/211 (14%)

Query: 878  CPNGCSGKGECLMGH------CQ-CQPGFGGDDCSKSVCPV--LCSQRGEYINGECQCNP 928
            C +G SG G+CL         C+ C PG  G  C    C V   C + G   +G C C+ 
Sbjct: 1985 CMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDE-GLGGSGSCFCDE 2043

Query: 929  GWKGKECSLRHDECEV--PDCNGHGHCVNG-KCSCVRGYK--GKFCGEID-CP--HPTCS 980
            GW G  C ++ +   V  P C     C  G  C C  GY+  G+ C   D C   H  CS
Sbjct: 2044 GWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCS 2103

Query: 981  GHGFCIE----GTCVCKKGWKGA--DCGTMDKDALQCLPDCSGHG---TFDVDTQTCSCH 1031
             H  C +     TC C   ++G    C   +         CS H    +  ++T+ C CH
Sbjct: 2104 EHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECH 2163

Query: 1032 AKWSGEDCSKEVCSLECGPH-GRCVGESCSC 1061
            A + G+      C  E  P   RC+G+   C
Sbjct: 2164 AGYVGDGLQ---CLEESEPPVDRCLGQPPPC 2191



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 83/272 (30%), Positives = 110/272 (40%), Gaps = 59/272 (21%)

Query: 895  CQPGFGGDDCSKSVCPV----LCSQRGEYI-----NGECQCNPGWKGKECSL-----RHD 940
            C  GF G DC++  CP      C  +G        NG C C P +KG  C +     +H 
Sbjct: 720  CCKGFFGPDCTQ--CPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHG 777

Query: 941  ECEVPDCN-GHGHCVN-----GKC---SCVRGYKGKFCGEI--DCPHPT-----CSGHGF 984
            E    DC   HG C N     G C   +C  G+ G+FC E   DC  PT     C  H  
Sbjct: 778  EQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDC-GPTGLAQHCHLHAR 836

Query: 985  CI--EGT--CVCKKGWK--GADCGTMDKDALQCLPDCSGHGTF---DVDTQTCSCHAKWS 1035
            C+  EG   C C  G++  G  C   +  +      CS +       + T  C+CH  WS
Sbjct: 837  CVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWS 896

Query: 1036 GED--C-SKEVCSLE----CGPHGRC----VGES-CSCAAGWSGEFCSVRLCDARCAEHG 1083
            G+   C + + C L+    C     C     G+S C+C  G++G+       D   A +G
Sbjct: 897  GDGRVCVAIDECELDVRGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNG 956

Query: 1084 QCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHG 1114
             C    TC  V G   R CT   CP    G G
Sbjct: 957  GCHGLATCRAVGG-GQRVCT---CPPGFGGDG 984



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 62/206 (30%), Positives = 85/206 (41%), Gaps = 38/206 (18%)

Query: 948  NGHGHCVNGKC-SCVRGYKGKFCGEI-DCPHPTC---SGHGFCIEGTCVCKKGWKGADC- 1001
            + H   +  KC +C R ++     ++ D P  +C   SG  F    +  C K  +  DC 
Sbjct: 1262 HSHAEALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSRGCSYTCAKKIQVPDCC 1321

Query: 1002 ----GTMDKDALQCLPD-CSGHGTFD---VDTQTCSCHAKWSGEDCSKEVCSLECGPHG- 1052
                GT+ +     L   CSGHG      + +  C CH  + G  C  EVC L  G +G 
Sbjct: 1322 PGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTAC--EVCEL--GRYGP 1377

Query: 1053 RCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHC----TLEGCPR 1108
             C G  C CA G         LC     + G   +G+C+C  GW G  C    T   CPR
Sbjct: 1378 NCTGV-CDCAHG---------LC-----QEGLQGDGSCVCNVGWQGLRCDQKITSPQCPR 1422

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGWDG 1134
             C  +  C  D+ G   C C  G+ G
Sbjct: 1423 KCDPNANCVQDSAGASTCACAAGYSG 1448



 Score = 61.3 bits (142), Expect = 5e-08
 Identities = 66/239 (27%), Positives = 86/239 (35%), Gaps = 43/239 (17%)

Query: 926  CNPGWKGKECSLRHDECEVPDCNGHGHCVNG-----KCSCVRGYKGKFC-----GEID-- 973
            C PG  G EC         P C+  G C++G     +C C  G+ G  C     G     
Sbjct: 1959 CCPGHYGSECQACPGGPSSP-CSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPH 2017

Query: 974  CPHPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTC 1028
            C    C+ HG C EG     +C C +GW G  C    +    C P C+            
Sbjct: 2018 CQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAV-------- 2069

Query: 1029 SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNG 1088
             C A   G  C    CSL     GR    +  C  G  G  CS     A C++ G     
Sbjct: 2070 -CRA---GNSCE---CSLGYEGDGRVCTVADLCQDGHGG--CSEH---ANCSQVGTMVTC 2117

Query: 1089 TCLC---VSGWN--GRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
            TCL      GW+   R+   +G    C+ H  C         C+C  G+ G     L+E
Sbjct: 2118 TCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEE 2176



 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 66/240 (27%), Positives = 93/240 (38%), Gaps = 49/240 (20%)

Query: 877  NCPNGCSGKGECL--------MGHCQCQPGFGGDDCSKSVCPV--LCSQRGEYINGECQ- 925
            NC +G  G G CL          H    P   G+ C +    V  LC  R     G CQ 
Sbjct: 745  NCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCDNR-PGSGGVCQQ 803

Query: 926  --CNPGWKGKECSLRHDECE----VPDCNGHGHCVN----GKCSCVRGYKGK--FCGEID 973
              C PG+ G+ C+    +C        C+ H  CV+     +C C+ G++G    C   +
Sbjct: 804  GTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSN 863

Query: 974  -CPHPT---CSGHGFCIEGT-----CVCKKGWKGAD--CGTMDKDALQCLPDCSGHGTFD 1022
             C HP    CS +  C+ G+     C C KGW G    C  +D+  L     C       
Sbjct: 864  PCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDVRGGCHTDALCS 923

Query: 1023 V---DTQTCSCHAKWSGE--DCSK-EVCSL-ECGPHG----RCVG---ESCSCAAGWSGE 1068
                    C+C   ++G+   CS  + C     G HG    R VG     C+C  G+ G+
Sbjct: 924  YVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGD 983



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 50/159 (31%), Positives = 61/159 (38%), Gaps = 30/159 (18%)

Query: 992  CKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSLEC 1048
            C KG+ G DC T           C G G      Q    C C   + G  C   +CS   
Sbjct: 720  CCKGFFGPDC-TQCPGGFS--NPCYGKGNCSDGIQGNGACLCFPDYKGIAC--HICS-NP 773

Query: 1049 GPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLE---- 1104
              HG    E C C  G         LCD R    G C+ GT  C  G++GR C       
Sbjct: 774  NKHGEQCQEDCGCVHG---------LCDNRPGSGGVCQQGT--CAPGFSGRFCNESMGDC 822

Query: 1105 ---GCPRSCAGHGQCRVDNDGRWECKCFDGW--DGPDCT 1138
               G  + C  H +C V  +G   C+C DG+  DG  CT
Sbjct: 823  GPTGLAQHCHLHARC-VSQEGVARCRCLDGFEGDGFSCT 860



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 61/220 (27%), Positives = 82/220 (37%), Gaps = 42/220 (19%)

Query: 885  KGECLMGH----CQCQPGFGGDDCS-KSVCPVLCSQRGEYINGECQCNPGWKGKECSL-- 937
            K  C  GH    CQ  PG     CS + VC       G   +G+C C  G+ G  C L  
Sbjct: 1956 KPSCCPGHYGSECQACPGGPSSPCSDRGVC-----MDGMSGSGQCLCRSGFAGTACELCA 2010

Query: 938  ---RHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFCGEIDCP-----HPTCSGHGF 984
                   C+   C  HG C      +G C C  G+ G  C E+         P C+    
Sbjct: 2011 PGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC-EVQLELQPVCTPPCAPEAV 2069

Query: 985  CIEG-TCVCKKGWKGADCGTMDKDALQ-CLPDCSGHGT-FDVDTQ-TCSCHAKWSGE--D 1038
            C  G +C C  G++G        D  Q     CS H     V T  TC+C   + G+   
Sbjct: 2070 CRAGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWS 2129

Query: 1039 C-SKEVCS----LECGPHGRCVG-----ESCSCAAGWSGE 1068
            C ++  C+      C  H  C+        C C AG+ G+
Sbjct: 2130 CRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGD 2169



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 63/237 (26%), Positives = 89/237 (37%), Gaps = 45/237 (18%)

Query: 933  KECSLRHDECEV----PDCNGHGHCVNGKCSCVRGYKGKFCGEIDCP---HPTCSGHGFC 985
            KEC   HD   +      C  + +    +  C +G+ G  C +  CP      C G G C
Sbjct: 689  KECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKGFFGPDCTQ--CPGGFSNPCYGKGNC 746

Query: 986  IEG-----TCVCKKGWKGADC---GTMDKDALQCLPDCSG-HGTFDVDTQTCSCHAKWSG 1036
             +G      C+C   +KG  C      +K   QC  DC   HG  D        +   SG
Sbjct: 747  SDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCD--------NRPGSG 798

Query: 1037 EDCSKEVCSLECGPHGRCVGESCS-CAAGWSGEFCSVRLCDARC-AEHGQCKNGTCLCVS 1094
              C +  C+   G  GR   ES   C      + C +    ARC ++ G  +   C C+ 
Sbjct: 799  GVCQQGTCAP--GFSGRFCNESMGDCGPTGLAQHCHLH---ARCVSQEGVAR---CRCLD 850

Query: 1095 GWNGR--HCTLEG-CPR----SCAGHGQCRVDNDGRWECKCFDGW--DGPDCTTLKE 1142
            G+ G    CT    C       C+ + +C   + G   C C  GW  DG  C  + E
Sbjct: 851  GFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDE 907



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/164 (26%), Positives = 56/164 (34%), Gaps = 27/164 (16%)

Query: 876  HNCPNG----CSGKGECL-----MGHCQCQPGFGGDDCSKSV--------CPVLCS---- 914
            H CP G    C+G G CL      G C CQ  F G  C +          C  +CS    
Sbjct: 110  HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG 169

Query: 915  --QRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHC--VNGKCSCVRGYKGKFCG 970
                G   +G C C  G+ G  C      C+   C  +  C      C C+ GY  +   
Sbjct: 170  VCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQ-GS 228

Query: 971  EIDCPHPTCSGHGFCIEGTCVCKKGWKGADC-GTMDKDALQCLP 1013
            E   P+P        +    V  KG     C      D + CLP
Sbjct: 229  ECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLP 272



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 35/108 (32%), Positives = 43/108 (39%), Gaps = 21/108 (19%)

Query: 1049 GPHGRCVGESC--SCAAGWSGEFCSVRLC----DARCAEHGQCKNGT-----CLCVSGWN 1097
            G H  CV  +   SC  G  G  C    C     + C++ G C +G      CLC SG+ 
Sbjct: 1945 GCHRNCVTTTWKPSCCPGHYGSECQA--CPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFA 2002

Query: 1098 GRHCTL-------EGCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G  C L         C    C  HG+C     G   C C +GW GP C
Sbjct: 2003 GTACELCAPGAFGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRC 2050



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 43/164 (26%), Positives = 63/164 (38%), Gaps = 18/164 (10%)

Query: 1019 GTFDVDTQTC-SCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDA 1077
            G   V +  C   HA+   E C        C   G  + ++   +  +   F   R C  
Sbjct: 1251 GVLTVGSSRCLHSHAEALREKCVNCTRRFRC-TQGFQLQDTPRKSCVYRSGFSFSRGCSY 1309

Query: 1078 RCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRS----CAGHGQCRVDNDGRWECKCFDGWD 1133
             CA+  Q  +    C  G+ G  C  E CP      C+GHGQC+    G  EC C +G+ 
Sbjct: 1310 TCAKKIQVPD----CCPGFFGTLC--EPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFH 1363

Query: 1134 GPDCTTLKEQICDDSRDNDK-DGLVDCEDPECCQSPACKSSQLC 1176
            G  C     ++C+  R      G+ DC    C +      S +C
Sbjct: 1364 GTAC-----EVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVC 1402



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 40/127 (31%), Positives = 52/127 (40%), Gaps = 17/127 (13%)

Query: 1024 DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHG 1083
            DT   SC  + SG   S+  CS  C    + V + C    G   E C   L    C+ HG
Sbjct: 1289 DTPRKSCVYR-SGFSFSRG-CSYTCAKKIQ-VPDCCPGFFGTLCEPCPGGLGGV-CSGHG 1344

Query: 1084 QCKN-----GTCLCVSGWNGRHCTLEGCPR---SCAG-----HGQCRVDNDGRWECKCFD 1130
            QC++     G C C  G++G  C +    R   +C G     HG C+    G   C C  
Sbjct: 1345 QCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGVCDCAHGLCQEGLQGDGSCVCNV 1404

Query: 1131 GWDGPDC 1137
            GW G  C
Sbjct: 1405 GWQGLRC 1411



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 32/125 (25%), Positives = 40/125 (32%), Gaps = 11/125 (8%)

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR-HCTLEGCPRSCAGH 1113
            + + C       G   S+  C  +C +  Q     C C   W  R H    G    C GH
Sbjct: 67   ITQDCRYEVQLGGSMVSMSGCRRKCRK--QVVQKAC-CPGYWGSRCHECPGGAETPCNGH 123

Query: 1114 GQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSR--DNDKDGLVDCEDPECCQSPACK 1171
            G C    D    C C + + G  C     Q C D      D   +  C    C   P   
Sbjct: 124  GTCLDGMDRNGTCVCQENFRGSAC-----QECQDPNRFGPDCQSVCSCVHGVCNHGPRGD 178

Query: 1172 SSQLC 1176
             S LC
Sbjct: 179  GSCLC 183


>D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein protein.
          Length = 1095

 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 82/293 (27%), Positives = 107/293 (36%), Gaps = 51/293 (17%)

Query: 893  CQCQPGFGGDDCSKSV--CPVLCSQRGEYINGE-----CQCNPGWKGKECSLRHDECEVP 945
            C C PGF G  C   V  C     Q G     +     CQC PG+ G+ CS   D C+  
Sbjct: 8    CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ 67

Query: 946  DCNGHGHCV----NGKCSCVRGYKGKFC-GEID-C---P-HP--TCSGHGFCIEGTCVCK 993
             C+ HG C        C+C  G+ G  C G++D C   P HP  T + H       C C 
Sbjct: 68   PCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCL 127

Query: 994  KGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT-----CSCHAKWSGEDCSKEVCSL-- 1046
             G  G  C  ++ D     P C   GT +    +     C C   + G  CS    S   
Sbjct: 128  PGHTGQWC-EVEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGF 185

Query: 1047 -ECGPHGRCVGE-------SCSCAAGWSGEFCSVRLCDARCAEHGQC-KNGTCLCVSGWN 1097
              C   G C+          C+C +G+ G  C        C     C  NG+C   +G  
Sbjct: 186  HHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLG 245

Query: 1098 GRHCTLEGCPRSCAGHGQCRV---------DNDGRWECKCF---DGWDGPDCT 1138
            G       CP S  G  +C+            DG  +  C      WDG DC+
Sbjct: 246  GPGFRC-SCPHSSPG-PRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCS 296



 Score = 68.1 bits (159), Expect = 5e-10
 Identities = 95/356 (26%), Positives = 124/356 (34%), Gaps = 69/356 (19%)

Query: 892  HCQCQPGFGG-------DDCSKSVC-PVLCSQRGEYING-ECQCNPGWKGKECSLRHDEC 942
            HC C PGF G       D+C    C P   +      N   CQC PG  G+ C +  D C
Sbjct: 83   HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPC 142

Query: 943  EVPDCNGHGHC-------VNGKCSCVRGYKGKFCGE--IDCPHPTCSGHGFCIEG----- 988
                C   G C       +   C C +G++G  C      C    C   G C+       
Sbjct: 143  HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGF 202

Query: 989  --TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSL 1046
               C C  G+ G DC T         P   G G        C     ++G  CS E   L
Sbjct: 203  PPRCACLSGYGGPDCLTP--------PAPKGCG----PPSPC----LYNG-SCS-ETTGL 244

Query: 1047 ECGPHGRCVGESCSCAAGWSGEFC---SVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL 1103
              GP     G  CSC     G  C     + C+ R  + G C  G       W+G  C+L
Sbjct: 245  G-GP-----GFRCSCPHSSPGPRCQKPGAKGCEGRSGD-GACDAGCSGPGGNWDGGDCSL 297

Query: 1104 EGCP---RSCAGHGQC-RVDNDGRWECKC------FDGWD---GPDCTTLKEQICDDSRD 1150
             G P   + C  H +C  +  DG+   +C      FDG+D    P CT   +Q C D   
Sbjct: 298  -GVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFH 356

Query: 1151 NDKDGLVDCEDPEC-CQSPACKSSQLCVSSPKPTDILLRKQPPAITASFFERMKFL 1205
            N       C   EC      C+             +L+   PPA+    F   + L
Sbjct: 357  NGHCE-KGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVL 411



 Score = 62.5 bits (145), Expect = 2e-08
 Identities = 58/214 (27%), Positives = 79/214 (36%), Gaps = 34/214 (15%)

Query: 958  CSCVRGYKGKFCGEI--DCPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC 1011
            C C  G++G  C +    C    C     C+       C C  G+ G +C + + DA Q 
Sbjct: 8    CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC-SKELDACQS 66

Query: 1012 LPDCSGHGTFDVDTQT--CSCHAKWSGEDCSKEV--C-SLECGPHGRCVGES------CS 1060
             P C  HGT         C+C   + G  C  +V  C    C P G     S      C 
Sbjct: 67   QP-CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQ 125

Query: 1061 CAAGWSGEFCSVRL--CDARCAEHGQCKNGT--------CLCVSGWNGRHCT--LEGCP- 1107
            C  G +G++C V +  C ++   HG     T        C C  G+ G  C+     C  
Sbjct: 126  CLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGF 185

Query: 1108 RSCAGHGQCRVDNDGRW--ECKCFDGWDGPDCTT 1139
              C   G C       +   C C  G+ GPDC T
Sbjct: 186  HHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLT 219



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 57/216 (26%), Positives = 77/216 (35%), Gaps = 46/216 (21%)

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ--TCSCHAKWSGEDCSKEV--C- 1044
            C C  G++G+ C     +  +  P C    T         C C   + G++CSKE+  C 
Sbjct: 8    CHCPPGFQGSLCQD-HVNPCESRP-CQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQ 65

Query: 1045 SLECGPHGRCV----GESCSCAAGWSGEFCS--VRLC-DARC------AEHGQCKNGTCL 1091
            S  C  HG C     G  C+C  G+ G  C   V  C D  C      A H       C 
Sbjct: 66   SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQ 125

Query: 1092 CVSGWNGRHCTLEGCP---RSCAGHGQCRVDNDGR--WECKCFDGWDGPDCTTLKEQICD 1146
            C+ G  G+ C +E  P   + C   G C         + C C  G++GP C+        
Sbjct: 126  CLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCS-------- 177

Query: 1147 DSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSPKP 1182
                              C    C    LC+ SPKP
Sbjct: 178  -------------HRAPSCGFHHCHHGGLCLPSPKP 200



 Score = 36.3 bits (80), Expect = 1.7
 Identities = 44/165 (26%), Positives = 56/165 (33%), Gaps = 31/165 (18%)

Query: 874  MTHNCPNGCSGKGECLM-GHCQCQPGFGGD----DCSKSVCPVLCSQRG----EYINGEC 924
            +T   P GC     CL  G C    G GG      C  S     C + G    E  +G+ 
Sbjct: 218  LTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDG 277

Query: 925  QCNPGWKGKECSLRHDECE--VPD----CNGHGHCV----NGKCSCVRGYKGKFCGEIDC 974
             C+ G  G   +    +C   VPD    C  H  C     +G+C      +       DC
Sbjct: 278  ACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDC 337

Query: 975  PHPT---------CSGH---GFCIEGTCVCKKGWKGADCGTMDKD 1007
              P          C  H   G C +G    + GW G DC   D D
Sbjct: 338  ETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGD 382


>AL359813-8|CAI23223.1|  377|Homo sapiens EGF-like-domain, multiple 9
            protein.
          Length = 377

 Score = 80.6 bits (190), Expect = 8e-14
 Identities = 72/242 (29%), Positives = 99/242 (40%), Gaps = 39/242 (16%)

Query: 888  CLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDEC-EVPD 946
            C++G    QP    DDCS S C +         +G C+C+PGW+G  C    + C  +P 
Sbjct: 15   CILG-APGQP-VRADDCS-SHCDLAHGCCAP--DGSCRCDPGWEGLHC----ERCVRMPG 65

Query: 947  CNGHGHCVNG-KCSCVRGYKGKFCGEIDCPHPTCSGHGFCI-----EGTCVCKKGWKGAD 1000
            C  HG C    +C C  G+  +       P   C   G C+     E  CVC  G+ G D
Sbjct: 66   CQ-HGTCHQPWQCICHSGWADEHICTTQSP---CQNGGQCMYDGGGEYHCVCLPGFHGRD 121

Query: 1001 CGTMDKDALQCLPDCSGHGTFDVDTQ-----TCSCHAKWSGEDCSKEV--CSLE-CGPHG 1052
            C        Q    C   G    D       TC C   + G  C   V  C +  C    
Sbjct: 122  CERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGA 181

Query: 1053 RCVGE----SCSCAAGWSGEFCSVRL--CDAR-CAEHGQCKNGT----CLCVSGWNGRHC 1101
             C+      SC C  G++G FC++ L  C +R C    +C++      CLC SG+ G+ C
Sbjct: 182  TCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTC 241

Query: 1102 TL 1103
             L
Sbjct: 242  EL 243



 Score = 79.4 bits (187), Expect = 2e-13
 Identities = 64/210 (30%), Positives = 93/210 (44%), Gaps = 36/210 (17%)

Query: 953  CVNGKCS-CVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDALQ 1010
            C++  C  C+ G  G+     DC       HG C  +G+C C  GW+G  C    +    
Sbjct: 7    CLHLVCLLCILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVR---- 62

Query: 1011 CLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLE--CGPHGRCV----GE-SCSCAA 1063
             +P C  HGT     Q C CH+ W+ E     +C+ +  C   G+C+    GE  C C  
Sbjct: 63   -MPGCQ-HGTCHQPWQ-CICHSGWADE----HICTTQSPCQNGGQCMYDGGGEYHCVCLP 115

Query: 1064 GWSGEFCSVRL--CD---ARCAEHGQCK-------NGTCLCVSGWNGRHC--TLEGC-PR 1108
            G+ G  C  +   C+   + C   GQC+       N TC C+ G+ G  C   ++ C  R
Sbjct: 116  GFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMR 175

Query: 1109 SCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             CA    C +D   R+ C C +G+ G  CT
Sbjct: 176  PCANGATC-LDGINRFSCLCPEGFAGRFCT 204



 Score = 72.5 bits (170), Expect = 2e-11
 Identities = 43/132 (32%), Positives = 58/132 (43%), Gaps = 10/132 (7%)

Query: 1036 GEDCSKEVCSLECG-PHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQCKNG-TCLC 1092
            G+    + CS  C   HG C  + SC C  GW G  C   +    C +HG C     C+C
Sbjct: 21   GQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGC-QHGTCHQPWQCIC 79

Query: 1093 VSGWNGRH-CTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDN 1151
             SGW   H CT +     C   GQC  D  G + C C  G+ G DC   K   C+ +   
Sbjct: 80   HSGWADEHICTTQS---PCQNGGQCMYDGGGEYHCVCLPGFHGRDCER-KAGPCEQAGSP 135

Query: 1152 DKDGLVDCEDPE 1163
             ++G   C+D +
Sbjct: 136  CRNG-GQCQDDQ 146



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 55/224 (24%), Positives = 84/224 (37%), Gaps = 32/224 (14%)

Query: 877  NCPNGCSGKGECLM--GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
            +C + C     C    G C+C PG+ G  C + V    C     +   +C C+ GW  + 
Sbjct: 28   DCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWADEH 87

Query: 935  CSLRHDECE-----VPDCNGHGHCVNGKCSCVRGYKGKFC----GEIDCPHPTC------ 979
                   C+     + D  G  HCV     C+ G+ G+ C    G  +     C      
Sbjct: 88   ICTTQSPCQNGGQCMYDGGGEYHCV-----CLPGFHGRDCERKAGPCEQAGSPCRNGGQC 142

Query: 980  -SGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFD-VDTQTCSCHAKWSG- 1036
                GF +  TC C  G+ GA C     D L   P  +G    D ++  +C C   ++G 
Sbjct: 143  QDDQGFALNFTCRCLVGFVGARCEVNVDDCLM-RPCANGATCLDGINRFSCLCPEGFAGR 201

Query: 1037 ------EDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRL 1074
                  +DC+   C        R     C C +G+ G+ C + L
Sbjct: 202  FCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVL 245


>DQ126100-1|AAZ38943.1|  212|Homo sapiens brevideltin protein.
          Length = 212

 Score = 79.8 bits (188), Expect = 1e-13
 Identities = 60/186 (32%), Positives = 77/186 (41%), Gaps = 20/186 (10%)

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE--SCSCAAGWSG 1067
            +C P C+    F  D   C C   W G  C + V S  C  HG C GE   C C  GW G
Sbjct: 25   ECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGC-LHGLC-GEPGQCICTDGWDG 82

Query: 1068 EFC--SVRLC-DARCAEHGQC---KNG--TCLCVSGWNGRHCTLEGCPRSCAG----HGQ 1115
            E C   VR C  A CA +G C    +G   C C  G++G+ C  +  P    G    HG 
Sbjct: 83   ELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGG 142

Query: 1116 CRVDNDGR---WECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKS 1172
              VD++GR     C C  G+ G  C  +      +  +ND     D      C+ PA   
Sbjct: 143  TCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCEND-GVCTDIGGDFRCRCPAGFI 201

Query: 1173 SQLCVS 1178
             + C S
Sbjct: 202  DKTCSS 207



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 58/188 (30%), Positives = 81/188 (43%), Gaps = 33/188 (17%)

Query: 977  PTCSG-HGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKW 1034
            P C+  +GFC +   C C+ GW+G  C     D     P C  HG      Q C C   W
Sbjct: 28   PACNPQNGFCEDDNVCRCQPGWQGPLC-----DQCVTSPGCL-HGLCGEPGQ-CICTDGW 80

Query: 1035 SGEDCSKEV--C-SLECGPHGRCVG-----ESCSCAAGWSGEFCSVR-----LCDARCAE 1081
             GE C ++V  C S  C  +G CV        CSCA G+SG+ C  +     +  + C  
Sbjct: 81   DGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQH 140

Query: 1082 HGQC-------KNGTCLCVSGWNGRHCTL--EGC-PRSCAGHGQCRVDNDGRWECKCFDG 1131
             G C        + +CLC  G++G  C +    C P  C   G C  D  G + C+C  G
Sbjct: 141  GGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC-TDIGGDFRCRCPAG 199

Query: 1132 WDGPDCTT 1139
            +    C++
Sbjct: 200  FIDKTCSS 207



 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 50/167 (29%), Positives = 69/167 (41%), Gaps = 22/167 (13%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C+CQPG+ G  C + V    C        G+C C  GW G+ C      C    C  +G 
Sbjct: 43   CRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGT 102

Query: 953  CVN-----GKCSCVRGYKGKFCGEIDCP----HPTCSGHGFCIE-------GTCVCKKGW 996
            CV+      +CSC  GY GK C + D P       C   G C++        +C+C  G+
Sbjct: 103  CVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162

Query: 997  KGADCGTMDKDALQCLPD-CSGHGT-FDVDTQ-TCSCHAKWSGEDCS 1040
             G  C  +   A  C P+ C   G   D+     C C A +  + CS
Sbjct: 163  SGNFCEIV---ANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCS 206



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 39/136 (28%), Positives = 54/136 (39%), Gaps = 23/136 (16%)

Query: 891  GHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYIN-----GECQCNPGWKGKECSLRHDEC 942
            G C C  G+ G+ C + V  C    C+  G  ++      EC C PG+ GK+C  +   C
Sbjct: 72   GQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPC 131

Query: 943  EV--PDCNGHGHCV-------NGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFC--IEG- 988
             +    C   G CV       +  C C  G+ G FC  +   C    C   G C  I G 
Sbjct: 132  VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGD 191

Query: 989  -TCVCKKGWKGADCGT 1003
              C C  G+    C +
Sbjct: 192  FRCRCPAGFIDKTCSS 207


>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
            protein-4 protein.
          Length = 1587

 Score = 79.0 bits (186), Expect = 2e-13
 Identities = 100/335 (29%), Positives = 138/335 (41%), Gaps = 68/335 (20%)

Query: 902  DDCSKSVCPVLCSQRG-EYINGE--CQCNPGWKGKECSLRHDEC--EVPDCNGHGHCVNG 956
            D+C++S  P LC + G + + G   C C  G++G  C    DEC  E P C G G C N 
Sbjct: 636  DECTQS--PGLCGRGGCKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPC-GPGRCDNT 692

Query: 957  ----KCSCVRGYK----GKFCGEID-CPH--PTCSGHGFC--IEGT--CVCKKGWK---- 997
                 C+C  G++    G  C ++D C    P C+ +G C   EG+  CVC  G++    
Sbjct: 693  AGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT-YGRCENTEGSFQCVCPMGFQPNTA 751

Query: 998  GADCGTMD--KDALQCL-PDC-SGHGTFDVDTQTC-SCHAKWSGEDCSKEVCSL---ECG 1049
            G++C  +D  ++ L C   +C +  G+F    +TC S H    G     + CS     CG
Sbjct: 752  GSECEDVDECENHLACPGQECVNSPGSF--QCRTCPSGHHLHRGRCTDVDECSSGAPPCG 809

Query: 1050 PHGRCVGES----CSCAAGW------SGEFCSVRLC--DARCAEHGQCKNG----TCLCV 1093
            PHG C        CSCA G+       G    V  C     C  HG+C N      C C 
Sbjct: 810  PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 869

Query: 1094 SGW----NGRHC-TLEGCPRSCAGHGQCRVDNDGRWECKCFDGW-DGPDCTTLKEQICDD 1147
             G+     G  C  ++ C            + DG +EC C  G   GPD  +     C D
Sbjct: 870  PGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLAS-----CLD 924

Query: 1148 SRDNDKDGLVDCEDPECCQSPACKSSQLCVSSPKP 1182
              +  + G   C    C  SP    S  CV    P
Sbjct: 925  VDECRERGPALCGSQRCENSP---GSYRCVRDCDP 956



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 68/267 (25%), Positives = 99/267 (37%), Gaps = 37/267 (13%)

Query: 945  PDCNGHGHCVNGK----CSCVRGYK----GKFCGEID-C---PHPTCSGHGFCIEGT--C 990
            P   G G C++      C+C  G++    G  C ++D C   P P   G      G+  C
Sbjct: 516  PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRC 575

Query: 991  VCKKGWKG----ADCGTMDKDALQCLPDCS-GHGTFDVDTQTCSCHAKWS----GEDCSK 1041
            VC  G++     A+C  +D +  +  P C  G       +  C C A +     G  C  
Sbjct: 576  VCGPGFRAGPRAAECLDVD-ECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 634

Query: 1042 -EVCSLECGPHGR--CVGES----CSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVS 1094
             + C+   G  GR  C        C C AG+ G  C   + D    E   C  G C   +
Sbjct: 635  VDECTQSPGLCGRGGCKNLPGSFRCVCPAGFRGSACEEDV-DECAQEPPPCGPGRCDNTA 693

Query: 1095 GWNGRHCTLEGCPRSCAGHGQCR-VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDK 1153
            G    HC      RS      C+ VD   R    C  G    +     + +C      + 
Sbjct: 694  G--SFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNT 750

Query: 1154 DGLVDCEDPECCQSPACKSSQLCVSSP 1180
             G  +CED + C++      Q CV+SP
Sbjct: 751  AGS-ECEDVDECENHLACPGQECVNSP 776



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 43/134 (32%), Positives = 64/134 (47%), Gaps = 25/134 (18%)

Query: 902  DDCSKSVCPVLC-SQRGEYINGE--C--QCNPGWK-GKECSLRH-DECEV--PDCNGHGH 952
            D+C +   P LC SQR E   G   C   C+PG+  G E +    DEC+   P+  G   
Sbjct: 926  DECRERG-PALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR 984

Query: 953  CVNG----KCS--CVRGYK---GKFCGEID-CPHPT-CSGHGFC--IEGT--CVCKKGWK 997
            C N     +C+  C  GY+   G  C ++D C + + C  H  C  + G+  C+C +G++
Sbjct: 985  CENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYE 1044

Query: 998  GADCGTMDKDALQC 1011
            GA  G    D  +C
Sbjct: 1045 GARDGRHCVDVNEC 1058


>DQ138965-1|AAZ66768.1|  203|Homo sapiens truncated brevideltinin
            protein.
          Length = 203

 Score = 79.0 bits (186), Expect = 2e-13
 Identities = 54/160 (33%), Positives = 69/160 (43%), Gaps = 19/160 (11%)

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE--SCSCAAGWSG 1067
            +C P C+    F  D   C C   W G  C + V S  C  HG C GE   C C  GW G
Sbjct: 25   ECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGC-LHGLC-GEPGQCICTDGWDG 82

Query: 1068 EFC--SVRLC-DARCAEHGQC---KNG--TCLCVSGWNGRHCTLEGCPRSCAG----HGQ 1115
            E C   VR C  A CA +G C    +G   C C  G++G+ C  +  P    G    HG 
Sbjct: 83   ELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGG 142

Query: 1116 CRVDNDGR---WECKCFDGWDGPDCTTLKEQICDDSRDND 1152
              VD++GR     C C  G+ G  C  +      +  +ND
Sbjct: 143  TCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCEND 182



 Score = 72.9 bits (171), Expect = 2e-11
 Identities = 56/177 (31%), Positives = 76/177 (42%), Gaps = 33/177 (18%)

Query: 977  PTCSG-HGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKW 1034
            P C+  +GFC +   C C+ GW+G  C     D     P C  HG      Q C C   W
Sbjct: 28   PACNPQNGFCEDDNVCRCQPGWQGPLC-----DQCVTSPGCL-HGLCGEPGQ-CICTDGW 80

Query: 1035 SGEDCSKEV--C-SLECGPHGRCVG-----ESCSCAAGWSGEFCSVR-----LCDARCAE 1081
             GE C ++V  C S  C  +G CV        CSCA G+SG+ C  +     +  + C  
Sbjct: 81   DGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQH 140

Query: 1082 HGQC-------KNGTCLCVSGWNGRHCTL--EGC-PRSCAGHGQCRVDNDGRWECKC 1128
             G C        + +CLC  G++G  C +    C P  C   G C  D  G + C+C
Sbjct: 141  GGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC-TDIGGDFRCRC 196



 Score = 66.5 bits (155), Expect = 1e-09
 Identities = 44/144 (30%), Positives = 60/144 (41%), Gaps = 20/144 (13%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C+CQPG+ G  C + V    C        G+C C  GW G+ C      C    C  +G 
Sbjct: 43   CRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGT 102

Query: 953  CVN-----GKCSCVRGYKGKFCGEIDCP----HPTCSGHGFCIE-------GTCVCKKGW 996
            CV+      +CSC  GY GK C + D P       C   G C++        +C+C  G+
Sbjct: 103  CVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162

Query: 997  KGADCGTMDKDALQCLPD-CSGHG 1019
             G  C  +   A  C P+ C   G
Sbjct: 163  SGNFCEIV---ANSCTPNPCENDG 183



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 45/143 (31%), Positives = 63/143 (44%), Gaps = 23/143 (16%)

Query: 924  CQCNPGWKGKECSLRHDECEV-PDCNGHGHCVN-GKCSCVRGYKGKFCGEI--DCPHPTC 979
            C+C PGW+G  C    D+C   P C  HG C   G+C C  G+ G+ C      C    C
Sbjct: 43   CRCQPGWQGPLC----DQCVTSPGCL-HGLCGEPGQCICTDGWDGELCDRDVRACSSAPC 97

Query: 980  SGHGFCI---EGT--CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ------TC 1028
            + +G C+   +G   C C  G+ G DC   D   +     C  HG   VD +      +C
Sbjct: 98   ANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQ-HGGTCVDDEGRASHASC 156

Query: 1029 SCHAKWSGEDCSKEVCSLECGPH 1051
             C   +SG  C  E+ +  C P+
Sbjct: 157  LCPPGFSGNFC--EIVANSCTPN 177



 Score = 53.6 bits (123), Expect = 1e-05
 Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 19/116 (16%)

Query: 891 GHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYIN-----GECQCNPGWKGKECSLRHDEC 942
           G C C  G+ G+ C + V  C    C+  G  ++      EC C PG+ GK+C  +   C
Sbjct: 72  GQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPC 131

Query: 943 EV--PDCNGHGHCV-------NGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFCIE 987
            +    C   G CV       +  C C  G+ G FC  +   C    C   G C +
Sbjct: 132 VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTD 187



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 21/100 (21%)

Query: 882 CSGKGECL-----MGHCQCQPGFGGDDCSKSVCPVL-----CSQRGEYINGE-------C 924
           C+  G C+     +  C C PG+ G DC K   P +     C   G  ++ E       C
Sbjct: 97  CANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASC 156

Query: 925 QCNPGWKGKECSLRHDECEVPDCNGHGHC--VNG--KCSC 960
            C PG+ G  C +  + C    C   G C  + G  +C C
Sbjct: 157 LCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC 196


>DQ017081-1|AAY40461.1|  315|Homo sapiens secredeltin protein.
          Length = 315

 Score = 79.0 bits (186), Expect = 2e-13
 Identities = 54/160 (33%), Positives = 69/160 (43%), Gaps = 19/160 (11%)

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE--SCSCAAGWSG 1067
            +C P C+    F  D   C C   W G  C + V S  C  HG C GE   C C  GW G
Sbjct: 25   ECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGC-LHGLC-GEPGQCICTDGWDG 82

Query: 1068 EFC--SVRLC-DARCAEHGQC---KNG--TCLCVSGWNGRHCTLEGCPRSCAG----HGQ 1115
            E C   VR C  A CA +G C    +G   C C  G++G+ C  +  P    G    HG 
Sbjct: 83   ELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGG 142

Query: 1116 CRVDNDGR---WECKCFDGWDGPDCTTLKEQICDDSRDND 1152
              VD++GR     C C  G+ G  C  +      +  +ND
Sbjct: 143  TCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCEND 182



 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 59/192 (30%), Positives = 82/192 (42%), Gaps = 33/192 (17%)

Query: 977  PTCSG-HGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKW 1034
            P C+  +GFC +   C C+ GW+G  C     D     P C  HG      Q C C   W
Sbjct: 28   PACNPQNGFCEDDNVCRCQPGWQGPLC-----DQCVTSPGCL-HGLCGEPGQ-CICTDGW 80

Query: 1035 SGEDCSKEV--C-SLECGPHGRCVG-----ESCSCAAGWSGEFCSVR-----LCDARCAE 1081
             GE C ++V  C S  C  +G CV        CSCA G+SG+ C  +     +  + C  
Sbjct: 81   DGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQH 140

Query: 1082 HGQC-------KNGTCLCVSGWNGRHCTL--EGC-PRSCAGHGQCRVDNDGRWECKCFDG 1131
             G C        + +CLC  G++G  C +    C P  C   G C  D  G + C+C  G
Sbjct: 141  GGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC-TDIGGDFRCRCPAG 199

Query: 1132 WDGPDCTTLKEQ 1143
            +    C+   +Q
Sbjct: 200  FIDKTCSRPVQQ 211



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 51/170 (30%), Positives = 71/170 (41%), Gaps = 22/170 (12%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C+CQPG+ G  C + V    C        G+C C  GW G+ C      C    C  +G 
Sbjct: 43   CRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGT 102

Query: 953  CVN-----GKCSCVRGYKGKFCGEIDCP----HPTCSGHGFCIE-------GTCVCKKGW 996
            CV+      +CSC  GY GK C + D P       C   G C++        +C+C  G+
Sbjct: 103  CVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162

Query: 997  KGADCGTMDKDALQCLPD-CSGHGT-FDVDTQ-TCSCHAKWSGEDCSKEV 1043
             G  C  +   A  C P+ C   G   D+     C C A +  + CS+ V
Sbjct: 163  SGNFCEIV---ANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPV 209



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 39/134 (29%), Positives = 53/134 (39%), Gaps = 23/134 (17%)

Query: 891  GHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYIN-----GECQCNPGWKGKECSLRHDEC 942
            G C C  G+ G+ C + V  C    C+  G  ++      EC C PG+ GK+C  +   C
Sbjct: 72   GQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPC 131

Query: 943  EV--PDCNGHGHCV-------NGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFC--IEG- 988
             +    C   G CV       +  C C  G+ G FC  +   C    C   G C  I G 
Sbjct: 132  VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGD 191

Query: 989  -TCVCKKGWKGADC 1001
              C C  G+    C
Sbjct: 192  FRCRCPAGFIDKTC 205


>BC014015-1|AAH14015.1|  383|Homo sapiens delta-like 1 homolog
            (Drosophila) protein.
          Length = 383

 Score = 79.0 bits (186), Expect = 2e-13
 Identities = 54/160 (33%), Positives = 69/160 (43%), Gaps = 19/160 (11%)

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE--SCSCAAGWSG 1067
            +C P C+    F  D   C C   W G  C + V S  C  HG C GE   C C  GW G
Sbjct: 25   ECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGC-LHGLC-GEPGQCICTDGWDG 82

Query: 1068 EFC--SVRLC-DARCAEHGQC---KNG--TCLCVSGWNGRHCTLEGCPRSCAG----HGQ 1115
            E C   VR C  A CA +G C    +G   C C  G++G+ C  +  P    G    HG 
Sbjct: 83   ELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGG 142

Query: 1116 CRVDNDGR---WECKCFDGWDGPDCTTLKEQICDDSRDND 1152
              VD++GR     C C  G+ G  C  +      +  +ND
Sbjct: 143  TCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCEND 182



 Score = 76.2 bits (179), Expect = 2e-12
 Identities = 60/205 (29%), Positives = 82/205 (40%), Gaps = 30/205 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C+CQPG+ G  C + V    C        G+C C  GW G+ C      C    C  +G 
Sbjct: 43   CRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGT 102

Query: 953  CVN-----GKCSCVRGYKGKFCGEIDCP----HPTCSGHGFCIE-------GTCVCKKGW 996
            CV+      +CSC  GY GK C + D P       C   G C++        +C+C  G+
Sbjct: 103  CVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162

Query: 997  KGADCGTMDKDALQCLPD-CSGHGT-FDVDTQ-TCSCHAKWSGEDCSKEV---CSLECGP 1050
             G  C  +   A  C P+ C   G   D+     C C A +  + CS+ V    S  C  
Sbjct: 163  SGNFCEIV---ANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQN 219

Query: 1051 HGRC-----VGESCSCAAGWSGEFC 1070
             G C     V   C C   ++G  C
Sbjct: 220  GGTCLQHTQVSYECLCKPEFTGLTC 244



 Score = 74.9 bits (176), Expect = 4e-12
 Identities = 58/187 (31%), Positives = 80/187 (42%), Gaps = 33/187 (17%)

Query: 977  PTCSG-HGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKW 1034
            P C+  +GFC +   C C+ GW+G  C     D     P C  HG      Q C C   W
Sbjct: 28   PACNPQNGFCEDDNVCRCQPGWQGPLC-----DQCVTSPGCL-HGLCGEPGQ-CICTDGW 80

Query: 1035 SGEDCSKEV--C-SLECGPHGRCVG-----ESCSCAAGWSGEFCSVR-----LCDARCAE 1081
             GE C ++V  C S  C  +G CV        CSCA G+SG+ C  +     +  + C  
Sbjct: 81   DGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQH 140

Query: 1082 HGQC-------KNGTCLCVSGWNGRHCTL--EGC-PRSCAGHGQCRVDNDGRWECKCFDG 1131
             G C        + +CLC  G++G  C +    C P  C   G C  D  G + C+C  G
Sbjct: 141  GGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC-TDIGGDFRCRCPAG 199

Query: 1132 WDGPDCT 1138
            +    C+
Sbjct: 200  FIDKTCS 206



 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 30/179 (16%)

Query: 891  GHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYIN-----GECQCNPGWKGKECSLRHDEC 942
            G C C  G+ G+ C + V  C    C+  G  ++      EC C PG+ GK+C  +   C
Sbjct: 72   GQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPC 131

Query: 943  EV--PDCNGHGHCV-------NGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFC--IEG- 988
             +    C   G CV       +  C C  G+ G FC  +   C    C   G C  I G 
Sbjct: 132  VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGD 191

Query: 989  -TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDTQT---CSCHAKWSGEDCSKE 1042
              C C  G+    C    +    C    C   GT    TQ    C C  +++G  C K+
Sbjct: 192  FRCRCPAGFIDKTC---SRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKK 247



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 29/97 (29%), Positives = 38/97 (39%), Gaps = 12/97 (12%)

Query: 885 KGECLMGHCQCQPGFGGDDC---SKSVCPVLCSQRG--EYINGE--CQCNPGWKGKECSL 937
           +G      C C PGF G+ C   + S  P  C   G    I G+  C+C  G+  K CS 
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207

Query: 938 RHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFC 969
               C    C   G C     V+ +C C   + G  C
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244


>BC013197-1|AAH13197.1|  383|Homo sapiens delta-like 1 homolog
            (Drosophila) protein.
          Length = 383

 Score = 79.0 bits (186), Expect = 2e-13
 Identities = 54/160 (33%), Positives = 69/160 (43%), Gaps = 19/160 (11%)

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE--SCSCAAGWSG 1067
            +C P C+    F  D   C C   W G  C + V S  C  HG C GE   C C  GW G
Sbjct: 25   ECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGC-LHGLC-GEPGQCICTDGWDG 82

Query: 1068 EFC--SVRLC-DARCAEHGQC---KNG--TCLCVSGWNGRHCTLEGCPRSCAG----HGQ 1115
            E C   VR C  A CA +G C    +G   C C  G++G+ C  +  P    G    HG 
Sbjct: 83   ELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGG 142

Query: 1116 CRVDNDGR---WECKCFDGWDGPDCTTLKEQICDDSRDND 1152
              VD++GR     C C  G+ G  C  +      +  +ND
Sbjct: 143  TCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCEND 182



 Score = 76.2 bits (179), Expect = 2e-12
 Identities = 60/205 (29%), Positives = 82/205 (40%), Gaps = 30/205 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C+CQPG+ G  C + V    C        G+C C  GW G+ C      C    C  +G 
Sbjct: 43   CRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGT 102

Query: 953  CVN-----GKCSCVRGYKGKFCGEIDCP----HPTCSGHGFCIE-------GTCVCKKGW 996
            CV+      +CSC  GY GK C + D P       C   G C++        +C+C  G+
Sbjct: 103  CVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162

Query: 997  KGADCGTMDKDALQCLPD-CSGHGT-FDVDTQ-TCSCHAKWSGEDCSKEV---CSLECGP 1050
             G  C  +   A  C P+ C   G   D+     C C A +  + CS+ V    S  C  
Sbjct: 163  SGNFCEIV---ANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQN 219

Query: 1051 HGRC-----VGESCSCAAGWSGEFC 1070
             G C     V   C C   ++G  C
Sbjct: 220  GGTCLQHTQVSYECLCKPEFTGLTC 244



 Score = 74.9 bits (176), Expect = 4e-12
 Identities = 58/187 (31%), Positives = 80/187 (42%), Gaps = 33/187 (17%)

Query: 977  PTCSG-HGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKW 1034
            P C+  +GFC +   C C+ GW+G  C     D     P C  HG      Q C C   W
Sbjct: 28   PACNPQNGFCEDDNVCRCQPGWQGPLC-----DQCVTSPGCL-HGLCGEPGQ-CICTDGW 80

Query: 1035 SGEDCSKEV--C-SLECGPHGRCVG-----ESCSCAAGWSGEFCSVR-----LCDARCAE 1081
             GE C ++V  C S  C  +G CV        CSCA G+SG+ C  +     +  + C  
Sbjct: 81   DGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQH 140

Query: 1082 HGQC-------KNGTCLCVSGWNGRHCTL--EGC-PRSCAGHGQCRVDNDGRWECKCFDG 1131
             G C        + +CLC  G++G  C +    C P  C   G C  D  G + C+C  G
Sbjct: 141  GGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC-TDIGGDFRCRCPAG 199

Query: 1132 WDGPDCT 1138
            +    C+
Sbjct: 200  FIDKTCS 206



 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 30/179 (16%)

Query: 891  GHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYIN-----GECQCNPGWKGKECSLRHDEC 942
            G C C  G+ G+ C + V  C    C+  G  ++      EC C PG+ GK+C  +   C
Sbjct: 72   GQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPC 131

Query: 943  EV--PDCNGHGHCV-------NGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFC--IEG- 988
             +    C   G CV       +  C C  G+ G FC  +   C    C   G C  I G 
Sbjct: 132  VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGD 191

Query: 989  -TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDTQT---CSCHAKWSGEDCSKE 1042
              C C  G+    C    +    C    C   GT    TQ    C C  +++G  C K+
Sbjct: 192  FRCRCPAGFIDKTC---SRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKK 247



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 29/97 (29%), Positives = 38/97 (39%), Gaps = 12/97 (12%)

Query: 885 KGECLMGHCQCQPGFGGDDC---SKSVCPVLCSQRG--EYINGE--CQCNPGWKGKECSL 937
           +G      C C PGF G+ C   + S  P  C   G    I G+  C+C  G+  K CS 
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207

Query: 938 RHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFC 969
               C    C   G C     V+ +C C   + G  C
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244


>BC007741-1|AAH07741.1|  383|Homo sapiens delta-like 1 homolog
            (Drosophila) protein.
          Length = 383

 Score = 79.0 bits (186), Expect = 2e-13
 Identities = 54/160 (33%), Positives = 69/160 (43%), Gaps = 19/160 (11%)

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE--SCSCAAGWSG 1067
            +C P C+    F  D   C C   W G  C + V S  C  HG C GE   C C  GW G
Sbjct: 25   ECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGC-LHGLC-GEPGQCICTDGWDG 82

Query: 1068 EFC--SVRLC-DARCAEHGQC---KNG--TCLCVSGWNGRHCTLEGCPRSCAG----HGQ 1115
            E C   VR C  A CA +G C    +G   C C  G++G+ C  +  P    G    HG 
Sbjct: 83   ELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGG 142

Query: 1116 CRVDNDGR---WECKCFDGWDGPDCTTLKEQICDDSRDND 1152
              VD++GR     C C  G+ G  C  +      +  +ND
Sbjct: 143  TCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCEND 182



 Score = 76.2 bits (179), Expect = 2e-12
 Identities = 60/205 (29%), Positives = 82/205 (40%), Gaps = 30/205 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C+CQPG+ G  C + V    C        G+C C  GW G+ C      C    C  +G 
Sbjct: 43   CRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGT 102

Query: 953  CVN-----GKCSCVRGYKGKFCGEIDCP----HPTCSGHGFCIE-------GTCVCKKGW 996
            CV+      +CSC  GY GK C + D P       C   G C++        +C+C  G+
Sbjct: 103  CVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162

Query: 997  KGADCGTMDKDALQCLPD-CSGHGT-FDVDTQ-TCSCHAKWSGEDCSKEV---CSLECGP 1050
             G  C  +   A  C P+ C   G   D+     C C A +  + CS+ V    S  C  
Sbjct: 163  SGNFCEIV---ANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQN 219

Query: 1051 HGRC-----VGESCSCAAGWSGEFC 1070
             G C     V   C C   ++G  C
Sbjct: 220  GGTCLQHTQVSYECLCKPEFTGLTC 244



 Score = 74.9 bits (176), Expect = 4e-12
 Identities = 58/187 (31%), Positives = 80/187 (42%), Gaps = 33/187 (17%)

Query: 977  PTCSG-HGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKW 1034
            P C+  +GFC +   C C+ GW+G  C     D     P C  HG      Q C C   W
Sbjct: 28   PACNPQNGFCEDDNVCRCQPGWQGPLC-----DQCVTSPGCL-HGLCGEPGQ-CICTDGW 80

Query: 1035 SGEDCSKEV--C-SLECGPHGRCVG-----ESCSCAAGWSGEFCSVR-----LCDARCAE 1081
             GE C ++V  C S  C  +G CV        CSCA G+SG+ C  +     +  + C  
Sbjct: 81   DGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQH 140

Query: 1082 HGQC-------KNGTCLCVSGWNGRHCTL--EGC-PRSCAGHGQCRVDNDGRWECKCFDG 1131
             G C        + +CLC  G++G  C +    C P  C   G C  D  G + C+C  G
Sbjct: 141  GGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC-TDIGGDFRCRCPAG 199

Query: 1132 WDGPDCT 1138
            +    C+
Sbjct: 200  FIDKTCS 206



 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 30/179 (16%)

Query: 891  GHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYIN-----GECQCNPGWKGKECSLRHDEC 942
            G C C  G+ G+ C + V  C    C+  G  ++      EC C PG+ GK+C  +   C
Sbjct: 72   GQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPC 131

Query: 943  EV--PDCNGHGHCV-------NGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFC--IEG- 988
             +    C   G CV       +  C C  G+ G FC  +   C    C   G C  I G 
Sbjct: 132  VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGD 191

Query: 989  -TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDTQT---CSCHAKWSGEDCSKE 1042
              C C  G+    C    +    C    C   GT    TQ    C C  +++G  C K+
Sbjct: 192  FRCRCPAGFIDKTC---SRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKK 247



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 29/97 (29%), Positives = 38/97 (39%), Gaps = 12/97 (12%)

Query: 885 KGECLMGHCQCQPGFGGDDC---SKSVCPVLCSQRG--EYINGE--CQCNPGWKGKECSL 937
           +G      C C PGF G+ C   + S  P  C   G    I G+  C+C  G+  K CS 
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207

Query: 938 RHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFC 969
               C    C   G C     V+ +C C   + G  C
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244


>AF187072-1|AAF08273.1|  515|Homo sapiens
            N-acetylglucosamine-1-phosphodiester
            alpha-N-acetylglucosaminidase protein.
          Length = 515

 Score = 79.0 bits (186), Expect = 2e-13
 Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 5/96 (5%)

Query: 911  VLCSQRGEYINGECQCN----PGWKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGY-K 965
            VL      Y +  CQ N    P        +    C+ PDC+GHG CV+G C C   + +
Sbjct: 294  VLNGTLASYPSDHCQDNMWRCPRQVSTVVCVHEPRCQPPDCHGHGTCVDGHCQCTGHFWR 353

Query: 966  GKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADC 1001
            G  C E+DC    CS HG C E  C C  GW G++C
Sbjct: 354  GPGCDELDCGPSNCSQHGLCTETGCRCDAGWTGSNC 389



 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 44/114 (38%), Positives = 54/114 (47%), Gaps = 15/114 (13%)

Query: 952  HCVNGKCSCVRGYKGKFC-GEIDCPHPTCSGHGFCIEGTCVCKKG-WKGADCGTMDKDAL 1009
            HC +    C R      C  E  C  P C GHG C++G C C    W+G  C     D L
Sbjct: 306  HCQDNMWRCPRQVSTVVCVHEPRCQPPDCHGHGTCVDGHCQCTGHFWRGPGC-----DEL 360

Query: 1010 QCLP-DCSGHGTFDVDTQT-CSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSC 1061
             C P +CS HG   + T+T C C A W+G +CS+E C L  G HG      C C
Sbjct: 361  DCGPSNCSQHG---LCTETGCRCDAGWTGSNCSEE-CPL--GWHGPGCQRRCKC 408



 Score = 64.5 bits (150), Expect = 6e-09
 Identities = 37/102 (36%), Positives = 47/102 (46%), Gaps = 10/102 (9%)

Query: 861 PQEISFVALVAEEMTHNCPNGCSGKGECLMGHCQCQPGFG-GDDCSKSVC-PVLCSQRGE 918
           P+++S V  V E      P  C G G C+ GHCQC   F  G  C +  C P  CSQ G 
Sbjct: 315 PRQVSTVVCVHEPRCQ--PPDCHGHGTCVDGHCQCTGHFWRGPGCDELDCGPSNCSQHGL 372

Query: 919 YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKCSC 960
                C+C+ GW G  CS   +EC +     HG     +C C
Sbjct: 373 CTETGCRCDAGWTGSNCS---EECPL---GWHGPGCQRRCKC 408



 Score = 58.0 bits (134), Expect = 5e-07
 Identities = 29/84 (34%), Positives = 37/84 (44%), Gaps = 4/84 (4%)

Query: 1047 ECGPHGRCVGESCSCAAG-WSGEFCSVRLCD-ARCAEHGQCKNGTCLCVSGWNGRHCTLE 1104
            +C  HG CV   C C    W G  C    C  + C++HG C    C C +GW G +C+ E
Sbjct: 333  DCHGHGTCVDGHCQCTGHFWRGPGCDELDCGPSNCSQHGLCTETGCRCDAGWTGSNCS-E 391

Query: 1105 GCPRSCAGHGQCRVDNDGRWECKC 1128
             CP    G G C+        C C
Sbjct: 392  ECPLGWHGPG-CQRRCKCEHHCPC 414



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 27/61 (44%), Positives = 29/61 (47%), Gaps = 4/61 (6%)

Query: 1013 PDCSGHGTFDVDTQTCSCHAK-WSGEDCSKEVCS-LECGPHGRCVGESCSCAAGWSGEFC 1070
            PDC GHGT  VD   C C    W G  C +  C    C  HG C    C C AGW+G  C
Sbjct: 332  PDCHGHGTC-VDGH-CQCTGHFWRGPGCDELDCGPSNCSQHGLCTETGCRCDAGWTGSNC 389

Query: 1071 S 1071
            S
Sbjct: 390  S 390



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 7/85 (8%)

Query: 910 PVLCSQRGEYINGECQCNPG-WKGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKF 968
           P  C   G  ++G CQC    W+G  C     +C   +C+ HG C    C C  G+ G  
Sbjct: 331 PPDCHGHGTCVDGHCQCTGHFWRGPGCD--ELDCGPSNCSQHGLCTETGCRCDAGWTGSN 388

Query: 969 CGEIDCPHPTCSGHGFCIEGTCVCK 993
           C E +CP      HG   +  C C+
Sbjct: 389 CSE-ECP---LGWHGPGCQRRCKCE 409



 Score = 46.4 bits (105), Expect = 0.002
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 1079 CAEHGQCKNGTCLCVSG-WNGRHCTLEGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C  HG C +G C C    W G  C    C P +C+ HG C         C+C  GW G +
Sbjct: 334  CHGHGTCVDGHCQCTGHFWRGPGCDELDCGPSNCSQHGLCTETG-----CRCDAGWTGSN 388

Query: 1137 CT 1138
            C+
Sbjct: 389  CS 390


>X53587-1|CAA37656.1| 1822|Homo sapiens integrin beta 4 protein
            protein.
          Length = 1822

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 57/187 (30%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 577

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESC-SC 1061
             +A  C+    G  +G    +   C CH +    D   E+      P G C    SC  C
Sbjct: 578  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHP-GLCEDLRSCVQC 635

Query: 1062 AAGWSGE 1068
             A  +GE
Sbjct: 636  QAWGTGE 642



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 28/162 (17%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 572

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC 1176
            C   L    C DS     +G   CE   C C   +  +  +C
Sbjct: 573  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTIC 614



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 468  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 528  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 588  GICNGRGHCECGRCHC 603



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 585 SNGGICNGRGHCEC 598


>X52186-1|CAA36433.1| 1805|Homo sapiens integrin beta 4 subunit
            protein.
          Length = 1805

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 57/187 (30%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 577

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESC-SC 1061
             +A  C+    G  +G    +   C CH +    D   E+      P G C    SC  C
Sbjct: 578  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHP-GLCEDLRSCVQC 635

Query: 1062 AAGWSGE 1068
             A  +GE
Sbjct: 636  QAWGTGE 642



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 28/162 (17%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 572

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC 1176
            C   L    C DS     +G   CE   C C   +  +  +C
Sbjct: 573  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTIC 614



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 468  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 528  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 588  GICNGRGHCECGRCHC 603



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 585 SNGGICNGRGHCEC 598


>X51841-1|CAA36134.1| 1752|Homo sapiens protein ( Human mRNA for
            integrin beta(4)subunit. ).
          Length = 1752

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 57/187 (30%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 577

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESC-SC 1061
             +A  C+    G  +G    +   C CH +    D   E+      P G C    SC  C
Sbjct: 578  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHP-GLCEDLRSCVQC 635

Query: 1062 AAGWSGE 1068
             A  +GE
Sbjct: 636  QAWGTGE 642



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 28/162 (17%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 572

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC 1176
            C   L    C DS     +G   CE   C C   +  +  +C
Sbjct: 573  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTIC 614



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 468  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 528  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 588  GICNGRGHCECGRCHC 603



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 585 SNGGICNGRGHCEC 598


>U66541-3|AAC51632.1| 1752|Homo sapiens beta4-integrin protein.
          Length = 1752

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 57/187 (30%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 577

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESC-SC 1061
             +A  C+    G  +G    +   C CH +    D   E+      P G C    SC  C
Sbjct: 578  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHP-GLCEDLRSCVQC 635

Query: 1062 AAGWSGE 1068
             A  +GE
Sbjct: 636  QAWGTGE 642



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 28/162 (17%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 572

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC 1176
            C   L    C DS     +G   CE   C C   +  +  +C
Sbjct: 573  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTIC 614



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 468  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 528  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 588  GICNGRGHCECGRCHC 603



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 585 SNGGICNGRGHCEC 598


>U66541-2|AAC51634.1| 1805|Homo sapiens beta4-integrin protein.
          Length = 1805

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 57/187 (30%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 577

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESC-SC 1061
             +A  C+    G  +G    +   C CH +    D   E+      P G C    SC  C
Sbjct: 578  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHP-GLCEDLRSCVQC 635

Query: 1062 AAGWSGE 1068
             A  +GE
Sbjct: 636  QAWGTGE 642



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 28/162 (17%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 572

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC 1176
            C   L    C DS     +G   CE   C C   +  +  +C
Sbjct: 573  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTIC 614



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 468  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 528  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 588  GICNGRGHCECGRCHC 603



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 585 SNGGICNGRGHCEC 598


>U66541-1|AAC51633.1| 1822|Homo sapiens beta4-integrin protein.
          Length = 1822

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 57/187 (30%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 577

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESC-SC 1061
             +A  C+    G  +G    +   C CH +    D   E+      P G C    SC  C
Sbjct: 578  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHP-GLCEDLRSCVQC 635

Query: 1062 AAGWSGE 1068
             A  +GE
Sbjct: 636  QAWGTGE 642



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 28/162 (17%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 572

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC 1176
            C   L    C DS     +G   CE   C C   +  +  +C
Sbjct: 573  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTIC 614



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 468  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 528  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 588  GICNGRGHCECGRCHC 603



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 585 SNGGICNGRGHCEC 598


>U15981-1|AAA75365.1|  310|Homo sapiens dlk protein.
          Length = 310

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 53/160 (33%), Positives = 68/160 (42%), Gaps = 19/160 (11%)

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE--SCSCAAGWSG 1067
            +C P C+    F  D   C C   W G  C + V S  C  HG C GE   C C  GW G
Sbjct: 25   ECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGC-LHGLC-GEPGQCICTDGWDG 82

Query: 1068 EFC--SVRLC-DARCAEHGQCKN-----GTCLCVSGWNGRHCTLEGCPRSCAG----HGQ 1115
            E C   VR C  A CA +G C +       C C  G++G+ C  +  P    G    HG 
Sbjct: 83   ELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGG 142

Query: 1116 CRVDNDGR---WECKCFDGWDGPDCTTLKEQICDDSRDND 1152
              VD++GR     C C  G+ G  C  +      +  +ND
Sbjct: 143  TCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCEND 182



 Score = 74.9 bits (176), Expect = 4e-12
 Identities = 58/187 (31%), Positives = 80/187 (42%), Gaps = 33/187 (17%)

Query: 977  PTCSG-HGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKW 1034
            P C+  +GFC +   C C+ GW+G  C     D     P C  HG      Q C C   W
Sbjct: 28   PACNPQNGFCEDDNVCRCQPGWQGPLC-----DQCVTSPGCL-HGLCGEPGQ-CICTDGW 80

Query: 1035 SGEDCSKEV--C-SLECGPHGRCVG-----ESCSCAAGWSGEFCSVR-----LCDARCAE 1081
             GE C ++V  C S  C  +G CV        CSCA G+SG+ C  +     +  + C  
Sbjct: 81   DGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQH 140

Query: 1082 HGQC-------KNGTCLCVSGWNGRHCTL--EGC-PRSCAGHGQCRVDNDGRWECKCFDG 1131
             G C        + +CLC  G++G  C +    C P  C   G C  D  G + C+C  G
Sbjct: 141  GGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC-TDIGGDFRCRCPAG 199

Query: 1132 WDGPDCT 1138
            +    C+
Sbjct: 200  FIDKTCS 206



 Score = 73.7 bits (173), Expect = 9e-12
 Identities = 52/177 (29%), Positives = 73/177 (41%), Gaps = 22/177 (12%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C+CQPG+ G  C + V    C        G+C C  GW G+ C      C    C  +G 
Sbjct: 43   CRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGT 102

Query: 953  CVN-----GKCSCVRGYKGKFCGEIDCP----HPTCSGHGFCIE-------GTCVCKKGW 996
            CV+      +CSC  GY GK C + D P       C   G C++        +C+C  G+
Sbjct: 103  CVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162

Query: 997  KGADCGTMDKDALQCLPD-CSGHGT-FDVDTQ-TCSCHAKWSGEDCSKEVCSLECGP 1050
             G  C  +   A  C P+ C   G   D+     C C A +  + CS+ V +    P
Sbjct: 163  SGNFCEIV---ANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSP 216



 Score = 54.8 bits (126), Expect = 5e-06
 Identities = 39/134 (29%), Positives = 53/134 (39%), Gaps = 23/134 (17%)

Query: 891  GHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYIN-----GECQCNPGWKGKECSLRHDEC 942
            G C C  G+ G+ C + V  C    C+  G  ++      EC C PG+ GK+C  +   C
Sbjct: 72   GQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPC 131

Query: 943  EV--PDCNGHGHCV-------NGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFC--IEG- 988
             +    C   G CV       +  C C  G+ G FC  +   C    C   G C  I G 
Sbjct: 132  VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGD 191

Query: 989  -TCVCKKGWKGADC 1001
              C C  G+    C
Sbjct: 192  FRCRCPAGFIDKTC 205



 Score = 38.7 bits (86), Expect = 0.32
 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 7/77 (9%)

Query: 885 KGECLMGHCQCQPGFGGDDC---SKSVCPVLCSQRGEY--INGE--CQCNPGWKGKECSL 937
           +G      C C PGF G+ C   + S  P  C   G    I G+  C+C  G+  K CS 
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207

Query: 938 RHDECEVPDCNGHGHCV 954
               C    C   G C+
Sbjct: 208 PVTNCASSPCQNGGTCL 224


>U15979-1|AAA75364.1|  382|Homo sapiens dlk protein.
          Length = 382

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 53/160 (33%), Positives = 68/160 (42%), Gaps = 19/160 (11%)

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE--SCSCAAGWSG 1067
            +C P C+    F  D   C C   W G  C + V S  C  HG C GE   C C  GW G
Sbjct: 25   ECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGC-LHGLC-GEPGQCICTDGWDG 82

Query: 1068 EFC--SVRLC-DARCAEHGQCKN-----GTCLCVSGWNGRHCTLEGCPRSCAG----HGQ 1115
            E C   VR C  A CA +G C +       C C  G++G+ C  +  P    G    HG 
Sbjct: 83   ELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGG 142

Query: 1116 CRVDNDGR---WECKCFDGWDGPDCTTLKEQICDDSRDND 1152
              VD++GR     C C  G+ G  C  +      +  +ND
Sbjct: 143  TCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCEND 182



 Score = 76.2 bits (179), Expect = 2e-12
 Identities = 60/205 (29%), Positives = 82/205 (40%), Gaps = 30/205 (14%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGH 952
            C+CQPG+ G  C + V    C        G+C C  GW G+ C      C    C  +G 
Sbjct: 43   CRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGT 102

Query: 953  CVN-----GKCSCVRGYKGKFCGEIDCP----HPTCSGHGFCIE-------GTCVCKKGW 996
            CV+      +CSC  GY GK C + D P       C   G C++        +C+C  G+
Sbjct: 103  CVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGF 162

Query: 997  KGADCGTMDKDALQCLPD-CSGHGT-FDVDTQ-TCSCHAKWSGEDCSKEV---CSLECGP 1050
             G  C  +   A  C P+ C   G   D+     C C A +  + CS+ V    S  C  
Sbjct: 163  SGNFCEIV---ANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQN 219

Query: 1051 HGRC-----VGESCSCAAGWSGEFC 1070
             G C     V   C C   ++G  C
Sbjct: 220  GGTCLQHTQVSYECLCKPEFTGLTC 244



 Score = 74.9 bits (176), Expect = 4e-12
 Identities = 58/187 (31%), Positives = 80/187 (42%), Gaps = 33/187 (17%)

Query: 977  PTCSG-HGFCIE-GTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKW 1034
            P C+  +GFC +   C C+ GW+G  C     D     P C  HG      Q C C   W
Sbjct: 28   PACNPQNGFCEDDNVCRCQPGWQGPLC-----DQCVTSPGCL-HGLCGEPGQ-CICTDGW 80

Query: 1035 SGEDCSKEV--C-SLECGPHGRCVG-----ESCSCAAGWSGEFCSVR-----LCDARCAE 1081
             GE C ++V  C S  C  +G CV        CSCA G+SG+ C  +     +  + C  
Sbjct: 81   DGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPCVINGSPCQH 140

Query: 1082 HGQC-------KNGTCLCVSGWNGRHCTL--EGC-PRSCAGHGQCRVDNDGRWECKCFDG 1131
             G C        + +CLC  G++G  C +    C P  C   G C  D  G + C+C  G
Sbjct: 141  GGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVC-TDIGGDFRCRCPAG 199

Query: 1132 WDGPDCT 1138
            +    C+
Sbjct: 200  FIDKTCS 206



 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 30/179 (16%)

Query: 891  GHCQCQPGFGGDDCSKSV--C-PVLCSQRGEYIN-----GECQCNPGWKGKECSLRHDEC 942
            G C C  G+ G+ C + V  C    C+  G  ++      EC C PG+ GK+C  +   C
Sbjct: 72   GQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDGPC 131

Query: 943  EV--PDCNGHGHCV-------NGKCSCVRGYKGKFCGEI--DCPHPTCSGHGFC--IEG- 988
             +    C   G CV       +  C C  G+ G FC  +   C    C   G C  I G 
Sbjct: 132  VINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGD 191

Query: 989  -TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTFDVDTQT---CSCHAKWSGEDCSKE 1042
              C C  G+    C    +    C    C   GT    TQ    C C  +++G  C K+
Sbjct: 192  FRCRCPAGFIDKTC---SRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKK 247



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 29/97 (29%), Positives = 38/97 (39%), Gaps = 12/97 (12%)

Query: 885 KGECLMGHCQCQPGFGGDDC---SKSVCPVLCSQRG--EYINGE--CQCNPGWKGKECSL 937
           +G      C C PGF G+ C   + S  P  C   G    I G+  C+C  G+  K CS 
Sbjct: 148 EGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSR 207

Query: 938 RHDECEVPDCNGHGHC-----VNGKCSCVRGYKGKFC 969
               C    C   G C     V+ +C C   + G  C
Sbjct: 208 PVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244


>BC126411-1|AAI26412.1| 1752|Homo sapiens integrin, beta 4 protein.
          Length = 1752

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 57/187 (30%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 577

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESC-SC 1061
             +A  C+    G  +G    +   C CH +    D   E+      P G C    SC  C
Sbjct: 578  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHP-GLCEDLRSCVQC 635

Query: 1062 AAGWSGE 1068
             A  +GE
Sbjct: 636  QAWGTGE 642



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 28/162 (17%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 572

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC 1176
            C   L    C DS     +G   CE   C C   +  +  +C
Sbjct: 573  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTIC 614



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 468  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 528  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 588  GICNGRGHCECGRCHC 603



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 585 SNGGICNGRGHCEC 598


>BC118916-1|AAI18917.1| 1752|Homo sapiens ITGB4 protein protein.
          Length = 1752

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 57/187 (30%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 577

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESC-SC 1061
             +A  C+    G  +G    +   C CH +    D   E+      P G C    SC  C
Sbjct: 578  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHP-GLCEDLRSCVQC 635

Query: 1062 AAGWSGE 1068
             A  +GE
Sbjct: 636  QAWGTGE 642



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 28/162 (17%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 572

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC 1176
            C   L    C DS     +G   CE   C C   +  +  +C
Sbjct: 573  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTIC 614



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 468  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 528  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 588  GICNGRGHCECGRCHC 603



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 585 SNGGICNGRGHCEC 598


>BC109238-1|AAI09239.1|  644|Homo sapiens ITGB4 protein protein.
          Length = 644

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 57/187 (30%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 375  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 434

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 435  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 494

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESC-SC 1061
             +A  C+    G  +G    +   C CH +    D   E+      P G C    SC  C
Sbjct: 495  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHP-GLCEDLRSCVQC 552

Query: 1062 AAGWSGE 1068
             A  +GE
Sbjct: 553  QAWGTGE 559



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 429 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 488

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 489 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 520



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 28/162 (17%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 375  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 434

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 435  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 489

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC 1176
            C   L    C DS     +G   CE   C C   +  +  +C
Sbjct: 490  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTIC 531



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 385  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 444

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 445  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 504

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 505  GICNGRGHCECGRCHC 520



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 385 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 444

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 445 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 501

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 502 SNGGICNGRGHCEC 515


>AF011375-1|AAB65421.1|  964|Homo sapiens integrin variant beta4E
            protein.
          Length = 964

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 57/187 (30%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 577

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESC-SC 1061
             +A  C+    G  +G    +   C CH +    D   E+      P G C    SC  C
Sbjct: 578  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHP-GLCEDLRSCVQC 635

Query: 1062 AAGWSGE 1068
             A  +GE
Sbjct: 636  QAWGTGE 642



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 512 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 571

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 572 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 603



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 28/162 (17%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 458  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 517

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 518  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 572

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC 1176
            C   L    C DS     +G   CE   C C   +  +  +C
Sbjct: 573  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTIC 614



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 468  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 528  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 587

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 588  GICNGRGHCECGRCHC 603



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 468 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 527

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 528 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 584

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 585 SNGGICNGRGHCEC 598


>AB208913-1|BAD92150.1| 1515|Homo sapiens integrin beta 4 isoform 3
            precursor variant protein.
          Length = 1515

 Score = 78.6 bits (185), Expect = 3e-13
 Identities = 57/187 (30%), Positives = 78/187 (41%), Gaps = 23/187 (12%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 490  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 549

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 550  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 609

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESC-SC 1061
             +A  C+    G  +G    +   C CH +    D   E+      P G C    SC  C
Sbjct: 610  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSAIHP-GLCEDLRSCVQC 667

Query: 1062 AAGWSGE 1068
             A  +GE
Sbjct: 668  QAWGTGE 674



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 544 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 603

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 604 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 635



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 47/162 (29%), Positives = 69/162 (42%), Gaps = 28/162 (17%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 490  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 549

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 550  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 604

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC 1176
            C   L    C DS     +G   CE   C C   +  +  +C
Sbjct: 605  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTIC 646



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 500  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 559

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 560  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 619

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 620  GICNGRGHCECGRCHC 635



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 500 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 559

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 560 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 616

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 617 SNGGICNGRGHCEC 630


>AJ251004-1|CAB61345.1| 1873|Homo sapiens integrin beta 4 protein.
          Length = 1873

 Score = 78.2 bits (184), Expect = 4e-13
 Identities = 53/182 (29%), Positives = 74/182 (40%), Gaps = 21/182 (11%)

Query: 903  DCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHD----------ECEVPDCNGHGH 952
            +  K V    CS  G+++ G+C C+ GW G+ C+              E E   C+G G 
Sbjct: 457  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 516

Query: 953  CVNGKCSCV-RG-YKGKFC--GEIDCPHPT---CSGHGFCIEGTCVCKKGWKGADCGTMD 1005
            C  G C C   G Y+G+FC      CP  +   C+  G C  G CVC+ GW G  C    
Sbjct: 517  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPL 576

Query: 1006 KDALQCLPDCSG--HGTFDVDTQTCSCHAKWSGEDCSKEV-CSLECGPHGRCVGESCSCA 1062
             +A  C+    G  +G    +   C CH +    D   E+  S       R    +CS  
Sbjct: 577  SNA-TCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSASTRASARTYAPACSAR 635

Query: 1063 AG 1064
             G
Sbjct: 636  RG 637



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 882 CSGKGECLMGHCQC--QPGFGGDDCSKS--VCP----VLCSQRGEYINGECQCNPGWKGK 933
           CSG+GEC  GHC C  +  + G  C      CP     LC+ RG    G+C C PGW G 
Sbjct: 511 CSGRGECQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGP 570

Query: 934 --ECSLRHDECEVPD---CNGHGHCVNGKCSC 960
             +C L +  C   +   CNG GHC  G+C C
Sbjct: 571 SCDCPLSNATCIDSNGGICNGRGHCECGRCHC 602



 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 52/183 (28%), Positives = 77/183 (42%), Gaps = 29/183 (15%)

Query: 1038 DCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCS--------VRLC-----DARCAEHGQ 1084
            +  KEV S  C  +G  V   C C+ GWSG+ C+        ++ C     D  C+  G+
Sbjct: 457  ELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGE 516

Query: 1085 CKNGTCLCV--SGWNGRHCTLEG--CPRS----CAGHGQCRVDNDGRWECKCFDGWDGPD 1136
            C+ G C+C     + G+ C  +   CPR+    C   G+C +      +C C  GW GP 
Sbjct: 517  CQCGHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMG-----QCVCEPGWTGPS 571

Query: 1137 C-TTLKEQICDDSRDNDKDGLVDCEDPEC-CQSPACKSSQLC-VSSPKPTDILLRKQPPA 1193
            C   L    C DS     +G   CE   C C   +  +  +C ++    T    R   PA
Sbjct: 572  CDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTDTICEINYSASTRASARTYAPA 631

Query: 1194 ITA 1196
             +A
Sbjct: 632  CSA 634



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 39/136 (28%), Positives = 51/136 (37%), Gaps = 22/136 (16%)

Query: 979  CSGHGFCIEGTCVCKKGWKGADCGTMD---KDALQCLPD-----CSGHGTFDVDTQTCSC 1030
            CS +G  + G CVC +GW G  C        D   CL +     CSG G        C  
Sbjct: 467  CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 526

Query: 1031 HAKWSGEDCSKE------VCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAE--- 1081
              ++ G+ C  +           C   GRC    C C  GW+G  C   L +A C +   
Sbjct: 527  EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNG 586

Query: 1082 -----HGQCKNGTCLC 1092
                  G C+ G C C
Sbjct: 587  GICNGRGHCECGRCHC 602



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 44/134 (32%), Positives = 57/134 (42%), Gaps = 26/134 (19%)

Query: 882 CSGKGECLMGHCQCQPGFGGDDCSKS------VCPVL-------CSQRGEYINGECQC-- 926
           CS  G+ + G C C  G+ G  C+ S      + P L       CS RGE   G C C  
Sbjct: 467 CSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYG 526

Query: 927 NPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFCGEIDCP--HPTC-- 979
              ++G+ C   + +C       CN  G C  G+C C  G+ G  C   DCP  + TC  
Sbjct: 527 EGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSC---DCPLSNATCID 583

Query: 980 SGHGFCI-EGTCVC 992
           S  G C   G C C
Sbjct: 584 SNGGICNGRGHCEC 597


>S80335-1|AAB21332.1|  798|Homo sapiens integrin beta 7 subunit
           protein.
          Length = 798

 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 47/142 (33%), Positives = 60/142 (42%), Gaps = 17/142 (11%)

Query: 863 EISFVALVAEEMTHNC--PNG----CSGKGECLMGHCQCQPGFGGD--DCSKSVCP---- 910
           E S   L + ++   C  PNG    CSGKG C  G C C     G   +C  + C     
Sbjct: 512 ECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGRCSCSGQSSGHLCECDDASCERHEG 571

Query: 911 VLCSQRGEYINGECQCNPGWKGK--ECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYK 965
           +LC   G    G C C+    G+  ECS   D C  P+   C+GHG C   +C C+ GY 
Sbjct: 572 ILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCISPEGGLCSGHGRCKCNRCQCLDGYY 631

Query: 966 GKFCGEIDCPHPTCSGHGFCIE 987
           G  C +       C  H  C E
Sbjct: 632 GALCDQCPGCKTPCERHRDCAE 653



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 54/181 (29%), Positives = 67/181 (37%), Gaps = 29/181 (16%)

Query: 879  PNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV-----------------LCSQRGEYIN 921
            P+   G+G    G C C PG  G  C  SV  +                 LCS +G    
Sbjct: 486  PHCSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQC 545

Query: 922  GECQCNPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFC---GEID-C 974
            G C C+    G  C      CE  +   C G G C  G C C     G+ C   G++D C
Sbjct: 546  GRCSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSC 605

Query: 975  PHP---TCSGHGFCIEGTCVCKKGWKGADCGTMD--KDALQCLPDCSGHGTFDVDTQTCS 1029
              P    CSGHG C    C C  G+ GA C      K   +   DC+  G F       +
Sbjct: 606  ISPEGGLCSGHGRCKCNRCQCLDGYYGALCDQCPGCKTPCERHRDCAECGAFRTGPLATN 665

Query: 1030 C 1030
            C
Sbjct: 666  C 666



 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 32/192 (16%)

Query: 913  CSQ-RGEYINGECQCNPGWKGK--ECSLR-------HDECEVPD-----CNGHGHCVNGK 957
            CS  +G    G C C PG  G+  ECS+           C  P+     C+G GHC  G+
Sbjct: 488  CSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGR 547

Query: 958  CSCVRGYKGKF--CGEIDCPHP---TCSGHGFCIEGTCVCKKGWKGADC---GTMDKDAL 1009
            CSC     G    C +  C       C G G C  G C C     G  C   G MD    
Sbjct: 548  CSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCIS 607

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK-EVCSLECGPHGRCVGESCSCAAGWSGE 1068
                 CSGHG        C C   + G  C +   C   C  H  C      C A  +G 
Sbjct: 608  PEGGLCSGHGR--CKCNRCQCLDGYYGALCDQCPGCKTPCERHRDC----AECGAFRTGP 661

Query: 1069 FCSVRLCDARCA 1080
              +   C   CA
Sbjct: 662  LAT--NCSTACA 671



 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 35/106 (33%), Positives = 45/106 (42%), Gaps = 23/106 (21%)

Query: 1048 CGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH--------GQCKNGTCLCVSGWNGR 1099
            C   G C    CSC+   SG  C     DA C  H        G+C+ G C C +   GR
Sbjct: 537  CSGKGHCQCGRCSCSGQSSGHLCECD--DASCERHEGILCGGFGRCQCGVCHCHANRTGR 594

Query: 1100 HCTLEG----C--PRS--CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C   G    C  P    C+GHG+C+ +      C+C DG+ G  C
Sbjct: 595  ACECSGDMDSCISPEGGLCSGHGRCKCN-----RCQCLDGYYGALC 635


>S49378-1|AAB23688.1|  798|Homo sapiens integrin beta 7 subunit
           protein.
          Length = 798

 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 47/142 (33%), Positives = 60/142 (42%), Gaps = 17/142 (11%)

Query: 863 EISFVALVAEEMTHNC--PNG----CSGKGECLMGHCQCQPGFGGD--DCSKSVCP---- 910
           E S   L + ++   C  PNG    CSGKG C  G C C     G   +C  + C     
Sbjct: 512 ECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGRCSCSGQSSGHLCECDDASCERHEG 571

Query: 911 VLCSQRGEYINGECQCNPGWKGK--ECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYK 965
           +LC   G    G C C+    G+  ECS   D C  P+   C+GHG C   +C C+ GY 
Sbjct: 572 ILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCISPEGGLCSGHGRCKCNRCQCLDGYY 631

Query: 966 GKFCGEIDCPHPTCSGHGFCIE 987
           G  C +       C  H  C E
Sbjct: 632 GALCDQCPGCKTPCERHRDCAE 653



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 54/181 (29%), Positives = 67/181 (37%), Gaps = 29/181 (16%)

Query: 879  PNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV-----------------LCSQRGEYIN 921
            P+   G+G    G C C PG  G  C  SV  +                 LCS +G    
Sbjct: 486  PHCSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQC 545

Query: 922  GECQCNPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFC---GEID-C 974
            G C C+    G  C      CE  +   C G G C  G C C     G+ C   G++D C
Sbjct: 546  GRCSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSC 605

Query: 975  PHP---TCSGHGFCIEGTCVCKKGWKGADCGTMD--KDALQCLPDCSGHGTFDVDTQTCS 1029
              P    CSGHG C    C C  G+ GA C      K   +   DC+  G F       +
Sbjct: 606  ISPEGGLCSGHGRCKCNRCQCLDGYYGALCDQCPGCKTPCERHRDCAECGAFRTGPLATN 665

Query: 1030 C 1030
            C
Sbjct: 666  C 666



 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 32/192 (16%)

Query: 913  CSQ-RGEYINGECQCNPGWKGK--ECSLR-------HDECEVPD-----CNGHGHCVNGK 957
            CS  +G    G C C PG  G+  ECS+           C  P+     C+G GHC  G+
Sbjct: 488  CSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGR 547

Query: 958  CSCVRGYKGKF--CGEIDCPHP---TCSGHGFCIEGTCVCKKGWKGADC---GTMDKDAL 1009
            CSC     G    C +  C       C G G C  G C C     G  C   G MD    
Sbjct: 548  CSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCIS 607

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK-EVCSLECGPHGRCVGESCSCAAGWSGE 1068
                 CSGHG        C C   + G  C +   C   C  H  C      C A  +G 
Sbjct: 608  PEGGLCSGHGR--CKCNRCQCLDGYYGALCDQCPGCKTPCERHRDC----AECGAFRTGP 661

Query: 1069 FCSVRLCDARCA 1080
              +   C   CA
Sbjct: 662  LAT--NCSTACA 671



 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 35/106 (33%), Positives = 45/106 (42%), Gaps = 23/106 (21%)

Query: 1048 CGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH--------GQCKNGTCLCVSGWNGR 1099
            C   G C    CSC+   SG  C     DA C  H        G+C+ G C C +   GR
Sbjct: 537  CSGKGHCQCGRCSCSGQSSGHLCECD--DASCERHEGILCGGFGRCQCGVCHCHANRTGR 594

Query: 1100 HCTLEG----C--PRS--CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C   G    C  P    C+GHG+C+ +      C+C DG+ G  C
Sbjct: 595  ACECSGDMDSCISPEGGLCSGHGRCKCN-----RCQCLDGYYGALC 635


>M68892-1|AAA59184.1|  798|Homo sapiens integrin beta-7 subunit
           protein.
          Length = 798

 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 47/142 (33%), Positives = 60/142 (42%), Gaps = 17/142 (11%)

Query: 863 EISFVALVAEEMTHNC--PNG----CSGKGECLMGHCQCQPGFGGD--DCSKSVCP---- 910
           E S   L + ++   C  PNG    CSGKG C  G C C     G   +C  + C     
Sbjct: 512 ECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGRCSCSGQSSGHLCECDDASCERHEG 571

Query: 911 VLCSQRGEYINGECQCNPGWKGK--ECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYK 965
           +LC   G    G C C+    G+  ECS   D C  P+   C+GHG C   +C C+ GY 
Sbjct: 572 ILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCISPEGGLCSGHGRCKCNRCQCLDGYY 631

Query: 966 GKFCGEIDCPHPTCSGHGFCIE 987
           G  C +       C  H  C E
Sbjct: 632 GALCDQCPGCKTPCERHRDCAE 653



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 54/181 (29%), Positives = 67/181 (37%), Gaps = 29/181 (16%)

Query: 879  PNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV-----------------LCSQRGEYIN 921
            P+   G+G    G C C PG  G  C  SV  +                 LCS +G    
Sbjct: 486  PHCSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQC 545

Query: 922  GECQCNPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFC---GEID-C 974
            G C C+    G  C      CE  +   C G G C  G C C     G+ C   G++D C
Sbjct: 546  GRCSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSC 605

Query: 975  PHP---TCSGHGFCIEGTCVCKKGWKGADCGTMD--KDALQCLPDCSGHGTFDVDTQTCS 1029
              P    CSGHG C    C C  G+ GA C      K   +   DC+  G F       +
Sbjct: 606  ISPEGGLCSGHGRCKCNRCQCLDGYYGALCDQCPGCKTPCERHRDCAECGAFRTGPLATN 665

Query: 1030 C 1030
            C
Sbjct: 666  C 666



 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 32/192 (16%)

Query: 913  CSQ-RGEYINGECQCNPGWKGK--ECSLR-------HDECEVPD-----CNGHGHCVNGK 957
            CS  +G    G C C PG  G+  ECS+           C  P+     C+G GHC  G+
Sbjct: 488  CSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGR 547

Query: 958  CSCVRGYKGKF--CGEIDCPHP---TCSGHGFCIEGTCVCKKGWKGADC---GTMDKDAL 1009
            CSC     G    C +  C       C G G C  G C C     G  C   G MD    
Sbjct: 548  CSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCIS 607

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK-EVCSLECGPHGRCVGESCSCAAGWSGE 1068
                 CSGHG        C C   + G  C +   C   C  H  C      C A  +G 
Sbjct: 608  PEGGLCSGHGR--CKCNRCQCLDGYYGALCDQCPGCKTPCERHRDC----AECGAFRTGP 661

Query: 1069 FCSVRLCDARCA 1080
              +   C   CA
Sbjct: 662  LAT--NCSTACA 671



 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 35/106 (33%), Positives = 45/106 (42%), Gaps = 23/106 (21%)

Query: 1048 CGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH--------GQCKNGTCLCVSGWNGR 1099
            C   G C    CSC+   SG  C     DA C  H        G+C+ G C C +   GR
Sbjct: 537  CSGKGHCQCGRCSCSGQSSGHLCECD--DASCERHEGILCGGFGRCQCGVCHCHANRTGR 594

Query: 1100 HCTLEG----C--PRS--CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C   G    C  P    C+GHG+C+ +      C+C DG+ G  C
Sbjct: 595  ACECSGDMDSCISPEGGLCSGHGRCKCN-----RCQCLDGYYGALC 635


>M62880-1|AAA59185.1|  798|Homo sapiens integrin beta-7 subunit
           protein.
          Length = 798

 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 47/142 (33%), Positives = 60/142 (42%), Gaps = 17/142 (11%)

Query: 863 EISFVALVAEEMTHNC--PNG----CSGKGECLMGHCQCQPGFGGD--DCSKSVCP---- 910
           E S   L + ++   C  PNG    CSGKG C  G C C     G   +C  + C     
Sbjct: 512 ECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGRCSCSGQSSGHLCECDDASCERHEG 571

Query: 911 VLCSQRGEYINGECQCNPGWKGK--ECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYK 965
           +LC   G    G C C+    G+  ECS   D C  P+   C+GHG C   +C C+ GY 
Sbjct: 572 ILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCISPEGGLCSGHGRCKCNRCQCLDGYY 631

Query: 966 GKFCGEIDCPHPTCSGHGFCIE 987
           G  C +       C  H  C E
Sbjct: 632 GALCDQCPGCKTPCERHRDCAE 653



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 54/181 (29%), Positives = 67/181 (37%), Gaps = 29/181 (16%)

Query: 879  PNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV-----------------LCSQRGEYIN 921
            P+   G+G    G C C PG  G  C  SV  +                 LCS +G    
Sbjct: 486  PHCSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQC 545

Query: 922  GECQCNPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFC---GEID-C 974
            G C C+    G  C      CE  +   C G G C  G C C     G+ C   G++D C
Sbjct: 546  GRCSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSC 605

Query: 975  PHP---TCSGHGFCIEGTCVCKKGWKGADCGTMD--KDALQCLPDCSGHGTFDVDTQTCS 1029
              P    CSGHG C    C C  G+ GA C      K   +   DC+  G F       +
Sbjct: 606  ISPEGGLCSGHGRCKCNRCQCLDGYYGALCDQCPGCKTPCERHRDCAECGAFRTGPLATN 665

Query: 1030 C 1030
            C
Sbjct: 666  C 666



 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 32/192 (16%)

Query: 913  CSQ-RGEYINGECQCNPGWKGK--ECSLR-------HDECEVPD-----CNGHGHCVNGK 957
            CS  +G    G C C PG  G+  ECS+           C  P+     C+G GHC  G+
Sbjct: 488  CSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGR 547

Query: 958  CSCVRGYKGKF--CGEIDCPHP---TCSGHGFCIEGTCVCKKGWKGADC---GTMDKDAL 1009
            CSC     G    C +  C       C G G C  G C C     G  C   G MD    
Sbjct: 548  CSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCIS 607

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK-EVCSLECGPHGRCVGESCSCAAGWSGE 1068
                 CSGHG        C C   + G  C +   C   C  H  C      C A  +G 
Sbjct: 608  PEGGLCSGHGR--CKCNRCQCLDGYYGALCDQCPGCKTPCERHRDC----AECGAFRTGP 661

Query: 1069 FCSVRLCDARCA 1080
              +   C   CA
Sbjct: 662  LAT--NCSTACA 671



 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 35/106 (33%), Positives = 45/106 (42%), Gaps = 23/106 (21%)

Query: 1048 CGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH--------GQCKNGTCLCVSGWNGR 1099
            C   G C    CSC+   SG  C     DA C  H        G+C+ G C C +   GR
Sbjct: 537  CSGKGHCQCGRCSCSGQSSGHLCECD--DASCERHEGILCGGFGRCQCGVCHCHANRTGR 594

Query: 1100 HCTLEG----C--PRS--CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C   G    C  P    C+GHG+C+ +      C+C DG+ G  C
Sbjct: 595  ACECSGDMDSCISPEGGLCSGHGRCKCN-----RCQCLDGYYGALC 635


>L23823-1|AAA36118.1|  798|Homo sapiens integrin beta 7 subunit
           protein.
          Length = 798

 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 47/142 (33%), Positives = 60/142 (42%), Gaps = 17/142 (11%)

Query: 863 EISFVALVAEEMTHNC--PNG----CSGKGECLMGHCQCQPGFGGD--DCSKSVCP---- 910
           E S   L + ++   C  PNG    CSGKG C  G C C     G   +C  + C     
Sbjct: 512 ECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGRCSCSGQSSGHLCECDDASCERHEG 571

Query: 911 VLCSQRGEYINGECQCNPGWKGK--ECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYK 965
           +LC   G    G C C+    G+  ECS   D C  P+   C+GHG C   +C C+ GY 
Sbjct: 572 ILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCISPEGGLCSGHGRCKCNRCQCLDGYY 631

Query: 966 GKFCGEIDCPHPTCSGHGFCIE 987
           G  C +       C  H  C E
Sbjct: 632 GALCDQCPGCKTPCERHRDCAE 653



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 54/181 (29%), Positives = 67/181 (37%), Gaps = 29/181 (16%)

Query: 879  PNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV-----------------LCSQRGEYIN 921
            P+   G+G    G C C PG  G  C  SV  +                 LCS +G    
Sbjct: 486  PHCSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQC 545

Query: 922  GECQCNPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFC---GEID-C 974
            G C C+    G  C      CE  +   C G G C  G C C     G+ C   G++D C
Sbjct: 546  GRCSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSC 605

Query: 975  PHP---TCSGHGFCIEGTCVCKKGWKGADCGTMD--KDALQCLPDCSGHGTFDVDTQTCS 1029
              P    CSGHG C    C C  G+ GA C      K   +   DC+  G F       +
Sbjct: 606  ISPEGGLCSGHGRCKCNRCQCLDGYYGALCDQCPGCKTPCERHRDCAECGAFRTGPLATN 665

Query: 1030 C 1030
            C
Sbjct: 666  C 666



 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 32/192 (16%)

Query: 913  CSQ-RGEYINGECQCNPGWKGK--ECSLR-------HDECEVPD-----CNGHGHCVNGK 957
            CS  +G    G C C PG  G+  ECS+           C  P+     C+G GHC  G+
Sbjct: 488  CSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGR 547

Query: 958  CSCVRGYKGKF--CGEIDCPHP---TCSGHGFCIEGTCVCKKGWKGADC---GTMDKDAL 1009
            CSC     G    C +  C       C G G C  G C C     G  C   G MD    
Sbjct: 548  CSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCIS 607

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK-EVCSLECGPHGRCVGESCSCAAGWSGE 1068
                 CSGHG        C C   + G  C +   C   C  H  C      C A  +G 
Sbjct: 608  PEGGLCSGHGR--CKCNRCQCLDGYYGALCDQCPGCKTPCERHRDC----AECGAFRTGP 661

Query: 1069 FCSVRLCDARCA 1080
              +   C   CA
Sbjct: 662  LAT--NCSTACA 671



 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 35/106 (33%), Positives = 45/106 (42%), Gaps = 23/106 (21%)

Query: 1048 CGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH--------GQCKNGTCLCVSGWNGR 1099
            C   G C    CSC+   SG  C     DA C  H        G+C+ G C C +   GR
Sbjct: 537  CSGKGHCQCGRCSCSGQSSGHLCECD--DASCERHEGILCGGFGRCQCGVCHCHANRTGR 594

Query: 1100 HCTLEG----C--PRS--CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C   G    C  P    C+GHG+C+ +      C+C DG+ G  C
Sbjct: 595  ACECSGDMDSCISPEGGLCSGHGRCKCN-----RCQCLDGYYGALC 635


>BC015916-1|AAH15916.1|  798|Homo sapiens ITGB7 protein protein.
          Length = 798

 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 47/142 (33%), Positives = 60/142 (42%), Gaps = 17/142 (11%)

Query: 863 EISFVALVAEEMTHNC--PNG----CSGKGECLMGHCQCQPGFGGD--DCSKSVCP---- 910
           E S   L + ++   C  PNG    CSGKG C  G C C     G   +C  + C     
Sbjct: 512 ECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGRCSCSGQSSGHLCECDDASCERHEG 571

Query: 911 VLCSQRGEYINGECQCNPGWKGK--ECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYK 965
           +LC   G    G C C+    G+  ECS   D C  P+   C+GHG C   +C C+ GY 
Sbjct: 572 ILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCISPEGGLCSGHGRCKCNRCQCLDGYY 631

Query: 966 GKFCGEIDCPHPTCSGHGFCIE 987
           G  C +       C  H  C E
Sbjct: 632 GALCDQCPGCKTPCERHRDCAE 653



 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 54/181 (29%), Positives = 67/181 (37%), Gaps = 29/181 (16%)

Query: 879  PNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV-----------------LCSQRGEYIN 921
            P+   G+G    G C C PG  G  C  SV  +                 LCS +G    
Sbjct: 486  PHCSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQC 545

Query: 922  GECQCNPGWKGKECSLRHDECEVPD---CNGHGHCVNGKCSCVRGYKGKFC---GEID-C 974
            G C C+    G  C      CE  +   C G G C  G C C     G+ C   G++D C
Sbjct: 546  GRCSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSC 605

Query: 975  PHP---TCSGHGFCIEGTCVCKKGWKGADCGTMD--KDALQCLPDCSGHGTFDVDTQTCS 1029
              P    CSGHG C    C C  G+ GA C      K   +   DC+  G F       +
Sbjct: 606  ISPEGGLCSGHGRCKCNRCQCLDGYYGALCDQCPGCKTPCERHRDCAECGAFRTGPLATN 665

Query: 1030 C 1030
            C
Sbjct: 666  C 666



 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 57/192 (29%), Positives = 68/192 (35%), Gaps = 32/192 (16%)

Query: 913  CSQ-RGEYINGECQCNPGWKGK--ECSLR-------HDECEVPD-----CNGHGHCVNGK 957
            CS  +G    G C C PG  G+  ECS+           C  P+     C+G GHC  G+
Sbjct: 488  CSDGQGHLQCGVCSCAPGRLGRLCECSVAELSSPDLESGCRAPNGTGPLCSGKGHCQCGR 547

Query: 958  CSCVRGYKGKF--CGEIDCPHP---TCSGHGFCIEGTCVCKKGWKGADC---GTMDKDAL 1009
            CSC     G    C +  C       C G G C  G C C     G  C   G MD    
Sbjct: 548  CSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCIS 607

Query: 1010 QCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSK-EVCSLECGPHGRCVGESCSCAAGWSGE 1068
                 CSGHG        C C   + G  C +   C   C  H  C      C A  +G 
Sbjct: 608  PEGGLCSGHGR--CKCNRCQCLDGYYGALCDQCPGCKTPCERHRDC----AECGAFRTGP 661

Query: 1069 FCSVRLCDARCA 1080
              +   C   CA
Sbjct: 662  LAT--NCSTACA 671



 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 35/106 (33%), Positives = 45/106 (42%), Gaps = 23/106 (21%)

Query: 1048 CGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH--------GQCKNGTCLCVSGWNGR 1099
            C   G C    CSC+   SG  C     DA C  H        G+C+ G C C +   GR
Sbjct: 537  CSGKGHCQCGRCSCSGQSSGHLCECD--DASCERHEGILCGGFGRCQCGVCHCHANRTGR 594

Query: 1100 HCTLEG----C--PRS--CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             C   G    C  P    C+GHG+C+ +      C+C DG+ G  C
Sbjct: 595  ACECSGDMDSCISPEGGLCSGHGRCKCN-----RCQCLDGYYGALC 635


>X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related precursor
            (AA -19 to 4525) protein.
          Length = 4544

 Score = 76.6 bits (180), Expect = 1e-12
 Identities = 40/155 (25%), Positives = 65/155 (41%), Gaps = 12/155 (7%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-----SCSCAAGWSGEFCSVRLCDARCAEH 1082
            C C  +++G+ C  + C   C   G C        +C C  G++G  C+ ++C   CA +
Sbjct: 4220 CRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANN 4279

Query: 1083 GQC-----KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C         C C+ G+ G  C    C   C   G C++  DG  +C+C   ++G  C
Sbjct: 4280 STCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYFEGSRC 4339

Query: 1138 TTLKEQICDDSR--DNDKDGLVDCEDPECCQSPAC 1170
               K   C +     N + G V C   +   +P+C
Sbjct: 4340 EVNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSC 4374



 Score = 74.1 bits (174), Expect = 7e-12
 Identities = 54/206 (26%), Positives = 79/206 (38%), Gaps = 22/206 (10%)

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSL 1046
            C C+  + G  C  +D    QC   C   GT         TC C   ++G  C+++VC+ 
Sbjct: 4220 CRCQPRYTGDKC-ELD----QCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAG 4274

Query: 1047 ECGPHGRCV-----GESCSCAAGWSGEFCSVRLCDARCAEHGQCK---NGT--CLCVSGW 1096
             C  +  C         C C  G+ G+ C  R C   C   G C+   +G+  C C + +
Sbjct: 4275 YCANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYF 4334

Query: 1097 NGRHCTLEGCPRSCAGHGQCRVD-NDGRWECKCFDGWDGPDCTTLKEQICD-DSRDNDKD 1154
             G  C +  C R C   G C V+   G   C C DG   P C T      +  S   +  
Sbjct: 4335 EGSRCEVNKCSR-CL-EGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSK 4392

Query: 1155 GLVDCEDPECCQSPACKSSQLCVSSP 1180
             + +C+ P     P C+        P
Sbjct: 4393 MMPECQCPPHMTGPRCEEHVFSQQQP 4418



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 54/196 (27%), Positives = 80/196 (40%), Gaps = 33/196 (16%)

Query: 878  CPNGCSGKGECL-----MGHCQCQPGFGGDDCSKSVCPVLCSQRGE-YIN----GECQCN 927
            C   C   G C      M  C+C  GF G  C++ VC   C+      +N     +C+C 
Sbjct: 4236 CWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCL 4295

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHC---VNG--KCSCVRGYKGKFCGEIDCPHPTCSGH 982
            PG+ G  C  R  +C    C   G C    +G  +C C   ++G  C E++     CS  
Sbjct: 4296 PGFLGDRCQYR--QCS-GYCENFGTCQMAADGSRQCRCTAYFEGSRC-EVN----KCSR- 4346

Query: 983  GFCIEGTCVCKKGWKGADC----GTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWS 1035
              C+EG CV  K      C    G +    L C+  CS  G+  ++++    C C    +
Sbjct: 4347 --CLEGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMT 4404

Query: 1036 GEDCSKEVCSLECGPH 1051
            G  C + V S +   H
Sbjct: 4405 GPRCEEHVFSQQQPGH 4420



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 10/104 (9%)

Query: 1044 CSLECGPHGRCVGES-----CSCAAGWSGEFCSVRLCDARCAEHGQCKNG-----TCLCV 1093
            C+L+C   G C   +     C C   ++G+ C +  C   C   G C        TC C 
Sbjct: 4200 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 4259

Query: 1094 SGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            +G+ G  CT + C   CA +  C V+   + +C+C  G+ G  C
Sbjct: 4260 TGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRC 4303



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 9/96 (9%)

Query: 1075 CDARCAEHGQC-----KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCF 1129
            C+ +C   G C     +   C C   + G  C L+ C   C   G C     G   C+C 
Sbjct: 4200 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 4259

Query: 1130 DGWDGPDCTTLKEQICDDSRDNDKDGLVD-CEDPEC 1164
             G+ GP CT   +Q+C     N+    V+    P+C
Sbjct: 4260 TGFTGPKCT---QQVCAGYCANNSTCTVNQGNQPQC 4292



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 53/217 (24%), Positives = 71/217 (32%), Gaps = 32/217 (14%)

Query: 878  CPNGCSGKGECLMG-----HCQCQPGFGGDDCSKSVCPVLCSQRGEYING-----ECQCN 927
            C   C   G C +       C+CQP + GD C    C   C   G           C+C 
Sbjct: 4200 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 4259

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFCGEIDCPHPTCSGHG 983
             G+ G +C+     C     N     VN     +C C+ G+ G  C    C    C   G
Sbjct: 4260 TGFTGPKCT--QQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQC-SGYCENFG 4316

Query: 984  FC---IEGT--CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
             C    +G+  C C   ++G+ C        +CL           D  TC+C        
Sbjct: 4317 TCQMAADGSRQCRCTAYFEGSRCEV--NKCSRCLEGACVVNKQSGDV-TCNCTDGRVAPS 4373

Query: 1039 CSKEVCSLECGPHGRCVGES-----CSCAAGWSGEFC 1070
            C    C   C   G C   S     C C    +G  C
Sbjct: 4374 CL--TCVGHCSNGGSCTMNSKMMPECQCPPHMTGPRC 4408


>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
          Length = 2911

 Score = 76.6 bits (180), Expect = 1e-12
 Identities = 76/280 (27%), Positives = 108/280 (38%), Gaps = 47/280 (16%)

Query: 892  HCQCQPGF----GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH-DECEVPD 946
            H  C PG+    GG+ C   +C   C          C C+ G     C  +   +C V  
Sbjct: 94   HSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRC 153

Query: 947  CNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDK 1006
             NG G C +  C C +GY G +CG+  C +  C   G CI   C C  G+ G  C   ++
Sbjct: 154  MNG-GTCADDHCQCQKGYIGTYCGQPVCEN-GCQNGGRCIAQPCACVYGFTGPQC---ER 208

Query: 1007 DALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWS 1066
            D        +G     V+ Q   C  + +G  C+K +C   C   GR  G  C       
Sbjct: 209  DYR------TGPCFTQVNNQ--MCQGQLTGIVCTKTLC---CATTGRAWGHPC------- 250

Query: 1067 GEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWEC 1126
             E C  +    R       + G C  V       C  +  P  C G G C ++  G +EC
Sbjct: 251  -EMCPAQPQPCRRGFIPNIRTGACQDVD-----EC--QAIPGICQG-GNC-INTVGSFEC 300

Query: 1127 KCFDGWDGPDCTTLKEQICDDSRDNDKDGLVD--CEDPEC 1164
            +C  G    + T    Q C+D    D+  ++   CE  EC
Sbjct: 301  RCPAGHKQSETT----QKCEDI---DECSIIPGICETGEC 333



 Score = 67.7 bits (158), Expect = 6e-10
 Identities = 93/338 (27%), Positives = 140/338 (41%), Gaps = 61/338 (18%)

Query: 893  CQCQPGFGG----------DDCS--KSVCPVLCSQ-RGEYINGECQCNPGWK----GKEC 935
            C C PG+            D+C      C   C+   G Y   EC C+ G+     G+ C
Sbjct: 1224 CSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSY---ECSCSEGYALMPDGRSC 1280

Query: 936  SLRHDECEV-PD-CNGHGHCVN----GKCSCVRGYKG----KFC---GEIDCPHPTCSGH 982
            +   DECE  PD C+G G C N     +C C  G+      K C    E D     C   
Sbjct: 1281 A-DIDECENNPDICDG-GQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICM-F 1337

Query: 983  GFC--IEGT--CVCKKGW--KGADCGTMDKDALQC-LPDCSGHGT-FDVDTQ-TCSCHAK 1033
            G C   +G+  C C+ G+  K    G  D D  +    +C  H +  ++     CSC   
Sbjct: 1338 GECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREG 1397

Query: 1034 WSGED--C-SKEVCSL---ECGPHGRCVGES----CSCAAGWSGEFCSVRLCDARCAEH- 1082
            W G    C   + CS    +C  + +CV       C+C+ G++G+  +    D  CAE+ 
Sbjct: 1398 WIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVD-ECAENI 1456

Query: 1083 GQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
              C+NG CL V G     C +   P S +    C+  ++  ++  C  G    +   +  
Sbjct: 1457 NLCENGQCLNVPGAYRCECEMGFTPASDSR--SCQDIDECSFQNICVSGTCN-NLPGMFH 1513

Query: 1143 QICDDSRDNDKDGLVDCEDPECCQSPACKSSQLCVSSP 1180
             ICDD  + D+ G  +C D + C  P    + LCV++P
Sbjct: 1514 CICDDGYELDRTG-GNCTDIDECADPINCVNGLCVNTP 1550



 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 87/346 (25%), Positives = 134/346 (38%), Gaps = 65/346 (18%)

Query: 904  CSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL---RHDECEVPD--CNGHGHCVNG-- 956
            C+  VC    +Q G +    C+C  G+   +  L     DEC   D  C  +  C+N   
Sbjct: 1818 CANGVC---INQIGSF---RCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPG 1871

Query: 957  --KCSCVRGYK----GKFCGEIDCPH-PTCSGHGFCIE--GT--CVCKKGWKGADCGTMD 1005
              +C C  G+K    G      +C   P    HG C++  G+  C+C  G+K +   TM 
Sbjct: 1872 SYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMC 1931

Query: 1006 KDALQCLPDCSGHGTF--DVDTQTCSCHAKWS---GEDC-SKEVCSLECGP---HGRCVG 1056
             D  +C     G+GT    V +  C C+  +      DC   + CS   G    +GRC  
Sbjct: 1932 MDVDECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFN 1991

Query: 1057 E----SCSCAAGW----SGEFC-SVRLCDA--RCAEHGQCKN--GT--CLCVSGW--NGR 1099
            E     C C  G+     G+ C     C A       G C+N  G+  C+C  G+     
Sbjct: 1992 EIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSE 2051

Query: 1100 HC-TLEGC---PRSCAGHGQCRVDNDGRWECKCFDGW----DGPDCTTLKEQICDDSRDN 1151
            +C  +  C   P  C   G C  +  G ++C C  G+    +G  C   ++  C  + +N
Sbjct: 2052 NCIDINECDEDPNICL-FGSC-TNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFEN 2109

Query: 1152 DKDGL---VDCEDPECCQS--PACKSSQLCVSSPKPTDILLRKQPP 1192
             K  +    +    +CC S  P       C   PK  ++  +   P
Sbjct: 2110 GKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCP 2155



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 74/281 (26%), Positives = 97/281 (34%), Gaps = 37/281 (13%)

Query: 878  CPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSL 937
            C   C   G C   HCQCQ G+ G  C + VC   C   G  I   C C  G+ G +C  
Sbjct: 149  CSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIAQPCACVYGFTGPQC-- 206

Query: 938  RHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPT--CSGH--GFCIEGTCVCK 993
               +     C      VN +  C     G  C +  C   T    GH    C      C+
Sbjct: 207  -ERDYRTGPCFTQ---VNNQ-MCQGQLTGIVCTKTLCCATTGRAWGHPCEMCPAQPQPCR 261

Query: 994  KGW-KGADCGT-MDKDALQCLPD-CSGHGTFD-VDTQTCSCHAKWSGEDCSK-----EVC 1044
            +G+      G   D D  Q +P  C G    + V +  C C A     + ++     + C
Sbjct: 262  RGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDEC 321

Query: 1045 SL-----ECGPHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTC--LCVSGW 1096
            S+     E G     VG   C C  G+       R  D R    G C +G     C    
Sbjct: 322  SIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRT---GMCFSGLVNGRCAQEL 378

Query: 1097 NGRHCTLEGC--PRSCAGHG----QCRVDNDGRWECKCFDG 1131
             GR   ++ C  P  C G G     C V     +   C DG
Sbjct: 379  PGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDG 419



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 90/357 (25%), Positives = 138/357 (38%), Gaps = 63/357 (17%)

Query: 879  PNGCSGKGECLMGHCQCQPG--FGGDDCSKSVCPV--LCSQRGEYINGECQCNPGWKG-- 932
            P   S + EC MG+ Q   G     D+C+ + C      +  G Y    C+C+ G++   
Sbjct: 511  PTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYY---CKCHAGFQRTP 567

Query: 933  -KECSLRHDECEVPD--CNGHGHCVNG----KCSCVRGYKGKFCGEIDCPHPTCSGHGFC 985
             K+  +  DEC      C  +G CVN     +C C  G++    G+    H  C+    C
Sbjct: 568  TKQACIDIDECIQNGVLCK-NGRCVNSDGSFQCICNAGFELTTDGKNCVDHDECTTTNMC 626

Query: 986  IEGTC---------VCKKGWKGADCGTMDKDALQCLPD--C-SGHGTFDVDTQTCSC--- 1030
            + G C         +CK G+  A  G    D  +C     C +GH      +  C C   
Sbjct: 627  LNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPG 686

Query: 1031 -HAKWSGEDC----SKEVC--SLECG----PHGRCVGES-CSCAAGWSGEFCSVRLCDAR 1078
                  G  C     +  C   ++ G    P    V +S C CA    G     + C A+
Sbjct: 687  LAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAK 746

Query: 1079 -CAE-HGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD--- 1133
              AE HG C +G  + V G +   C L+  P  CA +G C  +  G + C C  G++   
Sbjct: 747  NSAEFHGLCSSGVGITVDGRDINECALD--PDICA-NGICE-NLRGSYRCNCNSGYEPDA 802

Query: 1134 -GPDCTTLKE-----QICDDSRDNDKDGLVDCEDPE----CCQSPACKSSQLCVSSP 1180
             G +C  + E      +CD+    +  G   C  P       ++  C+    C S+P
Sbjct: 803  SGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNP 859



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 70/277 (25%), Positives = 109/277 (39%), Gaps = 52/277 (18%)

Query: 885  KGECLMG--HCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDEC 942
            KG C +     +C+    G       C  L +  G      C+ +         ++   C
Sbjct: 894  KGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCE-RCELDTACPRGLARIKGVTC 952

Query: 943  E-VPDCNGH-GHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGAD 1000
            E V +C    G C NG+C      KG F    +CP       G  ++GT       +   
Sbjct: 953  EDVNECEVFPGVCPNGRCV---NSKGSF--HCECPE------GLTLDGTGRVCLDIRMEQ 1001

Query: 1001 CGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGES-C 1059
            C  +  D  +C+    G   F +D   C+  A W G +C       EC   G    E+ C
Sbjct: 1002 C-YLKWDEDECIHPVPGK--FRMDACCCAVGAAW-GTECE------ECPKPGTKEYETLC 1051

Query: 1060 SCAAGWSGE---------FCSVRLCDA--RCAEHGQCKN--GT--CLCVSGW----NGRH 1100
               AG++           +  +  C A      +G+C+N  G+  C C SG+      R+
Sbjct: 1052 PRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERN 1111

Query: 1101 CT-LEGC---PRSCAGHGQCRVDNDGRWECKCFDGWD 1133
            CT ++ C   P  C G G C V+  G +EC+CF+G++
Sbjct: 1112 CTDIDECRISPDLC-GSGIC-VNTPGSFECECFEGYE 1146



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 75/290 (25%), Positives = 117/290 (40%), Gaps = 61/290 (21%)

Query: 923  ECQCNPGW----KGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEIDC 974
            +C C PG+     G+ C+   DEC+ P    +GHC+N     +C C  G      G + C
Sbjct: 639  KCICKPGFVLAPNGRYCT-DVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRV-C 696

Query: 975  --PHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCS-CH 1031
               H   + +G   +G CV  + + GA    + K    C     G G      + C  C 
Sbjct: 697  VDTHMRSTCYGGIKKGVCV--RPFPGA----VTKSECCCANPDYGFG------EPCQPCP 744

Query: 1032 AKWSGEDCSKEVCSLECG--PHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGT 1089
            AK S E     +CS   G    GR + E   CA     + C+  +C+     +       
Sbjct: 745  AKNSAE--FHGLCSSGVGITVDGRDINE---CAL--DPDICANGICENLRGSY------R 791

Query: 1090 CLCVSGW----NGRHC-TLEGC--PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKE 1142
            C C SG+    +GR+C  ++ C   R    +G CR +  G + C C  G+        + 
Sbjct: 792  CNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCR-NTPGSYSCTCPPGY----VFRTET 846

Query: 1143 QICDDSRDNDKDGLVD--CEDP----ECCQSPACKSSQ---LCVSSPKPT 1183
            + C+D  + + +  V+  C +      C  SP  K S    +C+ S K T
Sbjct: 847  ETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGT 896



 Score = 39.1 bits (87), Expect = 0.24
 Identities = 72/279 (25%), Positives = 101/279 (36%), Gaps = 46/279 (16%)

Query: 893  CQCQPGFG-GDDCSKSVCPVLCSQRGEYINGE-CQCNPGWKGKECSLRHD--EC-EVPDC 947
            C   PG G GD C       LC +  E    + C    G        R D  EC E P  
Sbjct: 2127 CSKMPGEGWGDPCE------LCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGI 2180

Query: 948  NGHGHCVNG----KCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGT 1003
              +G C+N     +C C  GY   + G        CS    C  GTC    G    +C  
Sbjct: 2181 CSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIG--SFECNC 2238

Query: 1004 MDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECG-PHGRCVGESCSCA 1062
             +      + +C        D   C+ +       C     S EC  P G  + E     
Sbjct: 2239 NEGFEPGPMMNCE-------DINECAQNPLLCALRCMNTFGSYECTCPIGYALREDQKMC 2291

Query: 1063 AGWSGEFCSVRLCDARCAEHG-QCKN--GT--CLCVSGW----NGRHCTLEGCPRSCAG- 1112
                 + C+  L D  C   G  CKN  GT  C+C  G     +G  C  E   R+  G 
Sbjct: 2292 KDL--DECAEGLHD--CESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGI 2347

Query: 1113 --HGQCRVDNDGRWECKCFDGW----DGPDCTTLKEQIC 1145
              +G+C V+  G + C+C +G+     G +C   ++ +C
Sbjct: 2348 CENGRC-VNIIGSYRCECNEGFQSSSSGTECLDNRQGLC 2385



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 42/166 (25%), Positives = 64/166 (38%), Gaps = 37/166 (22%)

Query: 876  HNCPNGCSGKGECLMGH-CQCQPGF--------GGDDCSKSVCPVLCSQRGEYING---- 922
            HNC   C      L G  C+C PGF          ++C     P+LC  +G   N     
Sbjct: 2540 HNCQFLCVNT---LGGFTCKCPPGFTQHHTACIDNNECGSQ--PLLCGGKGICQNTPGSF 2594

Query: 923  ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG--------KCSCVRGYKGKF----C- 969
             C+C  G+      L  ++  V +C+G+  C +G        +C C +GY   +    C 
Sbjct: 2595 SCECQRGFSLDATGLNCED--VDECDGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCV 2652

Query: 970  GEIDCPHPTCSGHGFCIE--GT--CVCKKGWKGADCGTMDKDALQC 1011
             E +C +P   G   C    G+  C C  G+      +   D  +C
Sbjct: 2653 DENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNEC 2698


>DQ314873-1|ABC40732.1| 4544|Homo sapiens low density
            lipoprotein-related protein 1 (alpha-2-macroglobulin
            receptor) protein.
          Length = 4544

 Score = 76.6 bits (180), Expect = 1e-12
 Identities = 40/155 (25%), Positives = 65/155 (41%), Gaps = 12/155 (7%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-----SCSCAAGWSGEFCSVRLCDARCAEH 1082
            C C  +++G+ C  + C   C   G C        +C C  G++G  C+ ++C   CA +
Sbjct: 4220 CRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANN 4279

Query: 1083 GQC-----KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C         C C+ G+ G  C    C   C   G C++  DG  +C+C   ++G  C
Sbjct: 4280 STCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYFEGSRC 4339

Query: 1138 TTLKEQICDDSR--DNDKDGLVDCEDPECCQSPAC 1170
               K   C +     N + G V C   +   +P+C
Sbjct: 4340 EVNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSC 4374



 Score = 74.1 bits (174), Expect = 7e-12
 Identities = 54/206 (26%), Positives = 79/206 (38%), Gaps = 22/206 (10%)

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSL 1046
            C C+  + G  C  +D    QC   C   GT         TC C   ++G  C+++VC+ 
Sbjct: 4220 CRCQPRYTGDKC-ELD----QCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAG 4274

Query: 1047 ECGPHGRCV-----GESCSCAAGWSGEFCSVRLCDARCAEHGQCK---NGT--CLCVSGW 1096
             C  +  C         C C  G+ G+ C  R C   C   G C+   +G+  C C + +
Sbjct: 4275 YCANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYF 4334

Query: 1097 NGRHCTLEGCPRSCAGHGQCRVD-NDGRWECKCFDGWDGPDCTTLKEQICD-DSRDNDKD 1154
             G  C +  C R C   G C V+   G   C C DG   P C T      +  S   +  
Sbjct: 4335 EGSRCEVNKCSR-CL-EGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSK 4392

Query: 1155 GLVDCEDPECCQSPACKSSQLCVSSP 1180
             + +C+ P     P C+        P
Sbjct: 4393 MMPECQCPPHMTGPRCEEHVFSQQQP 4418



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 54/196 (27%), Positives = 80/196 (40%), Gaps = 33/196 (16%)

Query: 878  CPNGCSGKGECL-----MGHCQCQPGFGGDDCSKSVCPVLCSQRGE-YIN----GECQCN 927
            C   C   G C      M  C+C  GF G  C++ VC   C+      +N     +C+C 
Sbjct: 4236 CWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCL 4295

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHC---VNG--KCSCVRGYKGKFCGEIDCPHPTCSGH 982
            PG+ G  C  R  +C    C   G C    +G  +C C   ++G  C E++     CS  
Sbjct: 4296 PGFLGDRCQYR--QCS-GYCENFGTCQMAADGSRQCRCTAYFEGSRC-EVN----KCSR- 4346

Query: 983  GFCIEGTCVCKKGWKGADC----GTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWS 1035
              C+EG CV  K      C    G +    L C+  CS  G+  ++++    C C    +
Sbjct: 4347 --CLEGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMT 4404

Query: 1036 GEDCSKEVCSLECGPH 1051
            G  C + V S +   H
Sbjct: 4405 GPRCEEHVFSQQQPGH 4420



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 10/104 (9%)

Query: 1044 CSLECGPHGRCVGES-----CSCAAGWSGEFCSVRLCDARCAEHGQCKNG-----TCLCV 1093
            C+L+C   G C   +     C C   ++G+ C +  C   C   G C        TC C 
Sbjct: 4200 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 4259

Query: 1094 SGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            +G+ G  CT + C   CA +  C V+   + +C+C  G+ G  C
Sbjct: 4260 TGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRC 4303



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 9/96 (9%)

Query: 1075 CDARCAEHGQC-----KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCF 1129
            C+ +C   G C     +   C C   + G  C L+ C   C   G C     G   C+C 
Sbjct: 4200 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 4259

Query: 1130 DGWDGPDCTTLKEQICDDSRDNDKDGLVD-CEDPEC 1164
             G+ GP CT   +Q+C     N+    V+    P+C
Sbjct: 4260 TGFTGPKCT---QQVCAGYCANNSTCTVNQGNQPQC 4292



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 53/217 (24%), Positives = 71/217 (32%), Gaps = 32/217 (14%)

Query: 878  CPNGCSGKGECLMG-----HCQCQPGFGGDDCSKSVCPVLCSQRGEYING-----ECQCN 927
            C   C   G C +       C+CQP + GD C    C   C   G           C+C 
Sbjct: 4200 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 4259

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFCGEIDCPHPTCSGHG 983
             G+ G +C+     C     N     VN     +C C+ G+ G  C    C    C   G
Sbjct: 4260 TGFTGPKCT--QQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQC-SGYCENFG 4316

Query: 984  FC---IEGT--CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
             C    +G+  C C   ++G+ C        +CL           D  TC+C        
Sbjct: 4317 TCQMAADGSRQCRCTAYFEGSRCEV--NKCSRCLEGACVVNKQSGDV-TCNCTDGRVAPS 4373

Query: 1039 CSKEVCSLECGPHGRCVGES-----CSCAAGWSGEFC 1070
            C    C   C   G C   S     C C    +G  C
Sbjct: 4374 CL--TCVGHCSNGGSCTMNSKMMPECQCPPHMTGPRC 4408


>AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-related
            protein protein.
          Length = 4544

 Score = 76.6 bits (180), Expect = 1e-12
 Identities = 40/155 (25%), Positives = 65/155 (41%), Gaps = 12/155 (7%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-----SCSCAAGWSGEFCSVRLCDARCAEH 1082
            C C  +++G+ C  + C   C   G C        +C C  G++G  C+ ++C   CA +
Sbjct: 4220 CRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANN 4279

Query: 1083 GQC-----KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C         C C+ G+ G  C    C   C   G C++  DG  +C+C   ++G  C
Sbjct: 4280 STCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYFEGSRC 4339

Query: 1138 TTLKEQICDDSR--DNDKDGLVDCEDPECCQSPAC 1170
               K   C +     N + G V C   +   +P+C
Sbjct: 4340 EVNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSC 4374



 Score = 74.1 bits (174), Expect = 7e-12
 Identities = 54/206 (26%), Positives = 79/206 (38%), Gaps = 22/206 (10%)

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSL 1046
            C C+  + G  C  +D    QC   C   GT         TC C   ++G  C+++VC+ 
Sbjct: 4220 CRCQPRYTGDKC-ELD----QCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAG 4274

Query: 1047 ECGPHGRCV-----GESCSCAAGWSGEFCSVRLCDARCAEHGQCK---NGT--CLCVSGW 1096
             C  +  C         C C  G+ G+ C  R C   C   G C+   +G+  C C + +
Sbjct: 4275 YCANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYF 4334

Query: 1097 NGRHCTLEGCPRSCAGHGQCRVD-NDGRWECKCFDGWDGPDCTTLKEQICD-DSRDNDKD 1154
             G  C +  C R C   G C V+   G   C C DG   P C T      +  S   +  
Sbjct: 4335 EGSRCEVNKCSR-CL-EGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSK 4392

Query: 1155 GLVDCEDPECCQSPACKSSQLCVSSP 1180
             + +C+ P     P C+        P
Sbjct: 4393 MMPECQCPPHMTGPRCEEHVFSQQQP 4418



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 54/196 (27%), Positives = 80/196 (40%), Gaps = 33/196 (16%)

Query: 878  CPNGCSGKGECL-----MGHCQCQPGFGGDDCSKSVCPVLCSQRGE-YIN----GECQCN 927
            C   C   G C      M  C+C  GF G  C++ VC   C+      +N     +C+C 
Sbjct: 4236 CWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCL 4295

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHC---VNG--KCSCVRGYKGKFCGEIDCPHPTCSGH 982
            PG+ G  C  R  +C    C   G C    +G  +C C   ++G  C E++     CS  
Sbjct: 4296 PGFLGDRCQYR--QCS-GYCENFGTCQMAADGSRQCRCTAYFEGSRC-EVN----KCSR- 4346

Query: 983  GFCIEGTCVCKKGWKGADC----GTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWS 1035
              C+EG CV  K      C    G +    L C+  CS  G+  ++++    C C    +
Sbjct: 4347 --CLEGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMT 4404

Query: 1036 GEDCSKEVCSLECGPH 1051
            G  C + V S +   H
Sbjct: 4405 GPRCEEHVFSQQQPGH 4420



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 10/104 (9%)

Query: 1044 CSLECGPHGRCVGES-----CSCAAGWSGEFCSVRLCDARCAEHGQCKNG-----TCLCV 1093
            C+L+C   G C   +     C C   ++G+ C +  C   C   G C        TC C 
Sbjct: 4200 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 4259

Query: 1094 SGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            +G+ G  CT + C   CA +  C V+   + +C+C  G+ G  C
Sbjct: 4260 TGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRC 4303



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 9/96 (9%)

Query: 1075 CDARCAEHGQC-----KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCF 1129
            C+ +C   G C     +   C C   + G  C L+ C   C   G C     G   C+C 
Sbjct: 4200 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 4259

Query: 1130 DGWDGPDCTTLKEQICDDSRDNDKDGLVD-CEDPEC 1164
             G+ GP CT   +Q+C     N+    V+    P+C
Sbjct: 4260 TGFTGPKCT---QQVCAGYCANNSTCTVNQGNQPQC 4292



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 53/217 (24%), Positives = 71/217 (32%), Gaps = 32/217 (14%)

Query: 878  CPNGCSGKGECLMG-----HCQCQPGFGGDDCSKSVCPVLCSQRGEYING-----ECQCN 927
            C   C   G C +       C+CQP + GD C    C   C   G           C+C 
Sbjct: 4200 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 4259

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFCGEIDCPHPTCSGHG 983
             G+ G +C+     C     N     VN     +C C+ G+ G  C    C    C   G
Sbjct: 4260 TGFTGPKCT--QQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQC-SGYCENFG 4316

Query: 984  FC---IEGT--CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
             C    +G+  C C   ++G+ C        +CL           D  TC+C        
Sbjct: 4317 TCQMAADGSRQCRCTAYFEGSRCEV--NKCSRCLEGACVVNKQSGDV-TCNCTDGRVAPS 4373

Query: 1039 CSKEVCSLECGPHGRCVGES-----CSCAAGWSGEFC 1070
            C    C   C   G C   S     C C    +G  C
Sbjct: 4374 CL--TCVGHCSNGGSCTMNSKMMPECQCPPHMTGPRC 4408


>AB209498-1|BAD92735.1| 2359|Homo sapiens low density
            lipoprotein-related protein 1 variant protein.
          Length = 2359

 Score = 76.6 bits (180), Expect = 1e-12
 Identities = 40/155 (25%), Positives = 65/155 (41%), Gaps = 12/155 (7%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-----SCSCAAGWSGEFCSVRLCDARCAEH 1082
            C C  +++G+ C  + C   C   G C        +C C  G++G  C+ ++C   CA +
Sbjct: 2035 CRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANN 2094

Query: 1083 GQC-----KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
              C         C C+ G+ G  C    C   C   G C++  DG  +C+C   ++G  C
Sbjct: 2095 STCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYFEGSRC 2154

Query: 1138 TTLKEQICDDSR--DNDKDGLVDCEDPECCQSPAC 1170
               K   C +     N + G V C   +   +P+C
Sbjct: 2155 EVNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSC 2189



 Score = 74.1 bits (174), Expect = 7e-12
 Identities = 54/206 (26%), Positives = 79/206 (38%), Gaps = 22/206 (10%)

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWSGEDCSKEVCSL 1046
            C C+  + G  C  +D    QC   C   GT         TC C   ++G  C+++VC+ 
Sbjct: 2035 CRCQPRYTGDKC-ELD----QCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAG 2089

Query: 1047 ECGPHGRCV-----GESCSCAAGWSGEFCSVRLCDARCAEHGQCK---NGT--CLCVSGW 1096
             C  +  C         C C  G+ G+ C  R C   C   G C+   +G+  C C + +
Sbjct: 2090 YCANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYF 2149

Query: 1097 NGRHCTLEGCPRSCAGHGQCRVD-NDGRWECKCFDGWDGPDCTTLKEQICD-DSRDNDKD 1154
             G  C +  C R C   G C V+   G   C C DG   P C T      +  S   +  
Sbjct: 2150 EGSRCEVNKCSR-CL-EGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSK 2207

Query: 1155 GLVDCEDPECCQSPACKSSQLCVSSP 1180
             + +C+ P     P C+        P
Sbjct: 2208 MMPECQCPPHMTGPRCEEHVFSQQQP 2233



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 54/196 (27%), Positives = 80/196 (40%), Gaps = 33/196 (16%)

Query: 878  CPNGCSGKGECL-----MGHCQCQPGFGGDDCSKSVCPVLCSQRGE-YIN----GECQCN 927
            C   C   G C      M  C+C  GF G  C++ VC   C+      +N     +C+C 
Sbjct: 2051 CWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCL 2110

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHC---VNG--KCSCVRGYKGKFCGEIDCPHPTCSGH 982
            PG+ G  C  R  +C    C   G C    +G  +C C   ++G  C E++     CS  
Sbjct: 2111 PGFLGDRCQYR--QCS-GYCENFGTCQMAADGSRQCRCTAYFEGSRC-EVN----KCSR- 2161

Query: 983  GFCIEGTCVCKKGWKGADC----GTMDKDALQCLPDCSGHGTFDVDTQ---TCSCHAKWS 1035
              C+EG CV  K      C    G +    L C+  CS  G+  ++++    C C    +
Sbjct: 2162 --CLEGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMT 2219

Query: 1036 GEDCSKEVCSLECGPH 1051
            G  C + V S +   H
Sbjct: 2220 GPRCEEHVFSQQQPGH 2235



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 10/104 (9%)

Query: 1044 CSLECGPHGRCVGES-----CSCAAGWSGEFCSVRLCDARCAEHGQCKNG-----TCLCV 1093
            C+L+C   G C   +     C C   ++G+ C +  C   C   G C        TC C 
Sbjct: 2015 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 2074

Query: 1094 SGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            +G+ G  CT + C   CA +  C V+   + +C+C  G+ G  C
Sbjct: 2075 TGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRC 2118



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 9/96 (9%)

Query: 1075 CDARCAEHGQC-----KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCF 1129
            C+ +C   G C     +   C C   + G  C L+ C   C   G C     G   C+C 
Sbjct: 2015 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 2074

Query: 1130 DGWDGPDCTTLKEQICDDSRDNDKDGLVD-CEDPEC 1164
             G+ GP CT   +Q+C     N+    V+    P+C
Sbjct: 2075 TGFTGPKCT---QQVCAGYCANNSTCTVNQGNQPQC 2107



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 53/217 (24%), Positives = 71/217 (32%), Gaps = 32/217 (14%)

Query: 878  CPNGCSGKGECLMG-----HCQCQPGFGGDDCSKSVCPVLCSQRGEYING-----ECQCN 927
            C   C   G C +       C+CQP + GD C    C   C   G           C+C 
Sbjct: 2015 CNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCP 2074

Query: 928  PGWKGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYKGKFCGEIDCPHPTCSGHG 983
             G+ G +C+     C     N     VN     +C C+ G+ G  C    C    C   G
Sbjct: 2075 TGFTGPKCT--QQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQYRQC-SGYCENFG 2131

Query: 984  FC---IEGT--CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGED 1038
             C    +G+  C C   ++G+ C        +CL           D  TC+C        
Sbjct: 2132 TCQMAADGSRQCRCTAYFEGSRCEV--NKCSRCLEGACVVNKQSGDV-TCNCTDGRVAPS 2188

Query: 1039 CSKEVCSLECGPHGRCVGES-----CSCAAGWSGEFC 1070
            C    C   C   G C   S     C C    +G  C
Sbjct: 2189 CL--TCVGHCSNGGSCTMNSKMMPECQCPPHMTGPRC 2223


>BX538049-1|CAD97988.1| 1323|Homo sapiens hypothetical protein
            protein.
          Length = 1323

 Score = 75.8 bits (178), Expect = 2e-12
 Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 2/80 (2%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            CSC   W G  C + +C L C   GRCV    C C  GW+G  C   +C + C   G+C 
Sbjct: 1240 CSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCV 1299

Query: 1086 KNGTCLCVSGWNGRHCTLEG 1105
            +   C C+S W G +C+ +G
Sbjct: 1300 RPNRCHCLSSWTGHNCSGKG 1319



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 6/113 (5%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            C  +  W+     + VC   C   G C    +CSC  GW G  C   +C   C   G+C 
Sbjct: 1208 CLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCV 1267

Query: 1086 KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                C C  GW G  C    C   C   G+C   N     C C   W G +C+
Sbjct: 1268 APYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPN----RCHCLSSWTGHNCS 1316



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C   C   G C   + C C  G+ G  C + +C + C   G  +   +C C PGW G  C
Sbjct: 1224 CRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRC 1283

Query: 936  SLRHDECEVPDCNGHGHCVN-GKCSCVRGYKGKFC 969
                  C+ P  NG G CV   +C C+  + G  C
Sbjct: 1284 HTA--VCQSPCLNG-GKCVRPNRCHCLSSWTGHNC 1315



 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 10/101 (9%)

Query: 942  CEVPDCNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEG-TCVCKKGWKGA 999
            C  P C   G C     CSC  G+ G+ C E  C  P C   G C+    C C  GW G+
Sbjct: 1224 CRFP-CQNGGICQRPNACSCPEGWMGRLCEEPICILP-CLNGGRCVAPYQCDCPPGWTGS 1281

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCS 1040
             C T       C   C   G   V    C C + W+G +CS
Sbjct: 1282 RCHT-----AVCQSPCLNGGKC-VRPNRCHCLSSWTGHNCS 1316



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            C   C   G C+  + C C PG+ G  C  +VC   C   G+ +    C C   W G  C
Sbjct: 1256 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 1315

Query: 936  S 936
            S
Sbjct: 1316 S 1316



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            W+       +C   C   G C+    C C  GW GR C    C   C   G+C       
Sbjct: 1214 WTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAP---- 1269

Query: 1124 WECKCFDGWDGPDCTT 1139
            ++C C  GW G  C T
Sbjct: 1270 YQCDCPPGWTGSRCHT 1285


>BC000218-1|AAH00218.1|  618|Homo sapiens delta-like 3 (Drosophila)
            protein.
          Length = 618

 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 75/256 (29%), Positives = 102/256 (39%), Gaps = 43/256 (16%)

Query: 878  CPNGCSGK-GECLM-GHCQCQPGFGGDDCSKSVCPVLC-SQRGEYINGECQCNPGWKGKE 934
            C  GCS + G C   G C+C  G+ G  C+  V    C S RG          PG     
Sbjct: 220  CRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPG----- 274

Query: 935  CSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIEG 988
                   C+   C   G C       +C+C RG+ G  C    + C    C   G C+ G
Sbjct: 275  ----PGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGG 330

Query: 989  T-------CVCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVD-TQTCSCHAKWSGEDC 1039
                    C C  G++G++C   +D+ +LQ  P  +G    D+     C C A ++G  C
Sbjct: 331  ADPDSAYICHCPPGFQGSNCEKRVDRCSLQ--PCRNGGLCLDLGHALRCRCRAGFAGPRC 388

Query: 1040 SKEV--CS-LECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-CAEHGQC---- 1085
              ++  C+   C   G CV       CSCA G+ G  C  R   C AR CA  G+C    
Sbjct: 389  EHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHF 448

Query: 1086 KNGTCLCVSGWNGRHC 1101
                C C  G+ G  C
Sbjct: 449  SGLVCACAPGYMGARC 464



 Score = 70.9 bits (166), Expect = 6e-11
 Identities = 80/276 (28%), Positives = 114/276 (41%), Gaps = 58/276 (21%)

Query: 894  QCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVP-----DCN 948
            +C+P   G  C++     LC  R    +   +C PG +   C+   DECE P      C+
Sbjct: 177  RCEPPAVGTACTR-----LCRPR----SAPSRCGPGLR--PCAPLEDECEAPLVCRAGCS 225

Query: 949  G-HGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDK 1006
              HG C   G+C C+ G+ G  C     P  T S         C+  +G   A  G +  
Sbjct: 226  PEHGFCEQPGECRCLEGWTGPLC---TVPVSTSS---------CLSPRGPSSATTGCLVP 273

Query: 1007 DALQCLPD-CSGHGTFDVDTQT--CSCHAKWSGEDCSKEVCSLEC--GP---HGRCVGES 1058
                C  + C+  G+     ++  C+C   + G  C  EV  + C  GP    G CVG +
Sbjct: 274  GPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRC--EVSGVTCADGPCFNGGLCVGGA 331

Query: 1059 -------CSCAAGWSGEFCSVRL--CDAR-CAEHGQCKN-G---TCLCVSGWNGRHCT-- 1102
                   C C  G+ G  C  R+  C  + C   G C + G    C C +G+ G  C   
Sbjct: 332  DPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHD 391

Query: 1103 LEGCP-RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L+ C  R+CA  G C V+  G   C C  G+ G DC
Sbjct: 392  LDDCAGRACANGGTC-VEGGGAHRCSCALGFGGRDC 426



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 34/119 (28%), Positives = 45/119 (37%), Gaps = 12/119 (10%)

Query: 1067 GEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAG-HGQCRVDNDGRWE 1125
            G  C+ RLC  R A   +C  G   C    +     L  C   C+  HG C  +  G  E
Sbjct: 184  GTACT-RLCRPRSAP-SRCGPGLRPCAPLEDECEAPLV-CRAGCSPEHGFC--EQPG--E 236

Query: 1126 CKCFDGWDGPDCTT-LKEQICDDSRDNDKDGLVDC--EDPECCQSPACKSSQLCVSSPK 1181
            C+C +GW GP CT  +    C   R         C    P  C    C +   C  +P+
Sbjct: 237  CRCLEGWTGPLCTVPVSTSSCLSPR-GPSSATTGCLVPGPGPCDGNPCANGGSCSETPR 294


>AF241373-1|AAF62542.1|  618|Homo sapiens DLL3 protein precursor
            protein.
          Length = 618

 Score = 75.4 bits (177), Expect = 3e-12
 Identities = 75/256 (29%), Positives = 102/256 (39%), Gaps = 43/256 (16%)

Query: 878  CPNGCSGK-GECLM-GHCQCQPGFGGDDCSKSVCPVLC-SQRGEYINGECQCNPGWKGKE 934
            C  GCS + G C   G C+C  G+ G  C+  V    C S RG          PG     
Sbjct: 220  CRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPG----- 274

Query: 935  CSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIEG 988
                   C+   C   G C       +C+C RG+ G  C    + C    C   G C+ G
Sbjct: 275  ----PGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGG 330

Query: 989  T-------CVCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVD-TQTCSCHAKWSGEDC 1039
                    C C  G++G++C   +D+ +LQ  P  +G    D+     C C A ++G  C
Sbjct: 331  ADPDSAYICHCPPGFQGSNCEKRVDRCSLQ--PCRNGGLCLDLGHALRCRCRAGFAGPRC 388

Query: 1040 SKEV--CS-LECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-CAEHGQC---- 1085
              ++  C+   C   G CV       CSCA G+ G  C  R   C AR CA  G+C    
Sbjct: 389  EHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHF 448

Query: 1086 KNGTCLCVSGWNGRHC 1101
                C C  G+ G  C
Sbjct: 449  SGLVCACAPGYMGARC 464



 Score = 70.9 bits (166), Expect = 6e-11
 Identities = 80/276 (28%), Positives = 114/276 (41%), Gaps = 58/276 (21%)

Query: 894  QCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVP-----DCN 948
            +C+P   G  C++     LC  R    +   +C PG +   C+   DECE P      C+
Sbjct: 177  RCEPPAVGTACTR-----LCRPR----SAPSRCGPGLR--PCAPLEDECEAPLVCRAGCS 225

Query: 949  G-HGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDK 1006
              HG C   G+C C+ G+ G  C     P  T S         C+  +G   A  G +  
Sbjct: 226  PEHGFCEQPGECRCLEGWTGPLC---TVPVSTSS---------CLSPRGPSSATTGCLVP 273

Query: 1007 DALQCLPD-CSGHGTFDVDTQT--CSCHAKWSGEDCSKEVCSLEC--GP---HGRCVGES 1058
                C  + C+  G+     ++  C+C   + G  C  EV  + C  GP    G CVG +
Sbjct: 274  GPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRC--EVSGVTCADGPCFNGGLCVGGA 331

Query: 1059 -------CSCAAGWSGEFCSVRL--CDAR-CAEHGQCKN-G---TCLCVSGWNGRHCT-- 1102
                   C C  G+ G  C  R+  C  + C   G C + G    C C +G+ G  C   
Sbjct: 332  DPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHD 391

Query: 1103 LEGCP-RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L+ C  R+CA  G C V+  G   C C  G+ G DC
Sbjct: 392  LDDCAGRACANGGTC-VEGGGAHRCSCALGFGGRDC 426



 Score = 36.7 bits (81), Expect = 1.3
 Identities = 34/119 (28%), Positives = 45/119 (37%), Gaps = 12/119 (10%)

Query: 1067 GEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAG-HGQCRVDNDGRWE 1125
            G  C+ RLC  R A   +C  G   C    +     L  C   C+  HG C  +  G  E
Sbjct: 184  GTACT-RLCRPRSAP-SRCGPGLRPCAPLEDECEAPLV-CRAGCSPEHGFC--EQPG--E 236

Query: 1126 CKCFDGWDGPDCTT-LKEQICDDSRDNDKDGLVDC--EDPECCQSPACKSSQLCVSSPK 1181
            C+C +GW GP CT  +    C   R         C    P  C    C +   C  +P+
Sbjct: 237  CRCLEGWTGPLCTVPVSTSSCLSPR-GPSSATTGCLVPGPGPCDGNPCANGGSCSETPR 294


>BX537918-1|CAD97901.1| 1441|Homo sapiens hypothetical protein
            protein.
          Length = 1441

 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            CSC   W G  C + +C L C   GRCV    C C  GW+G  C   +C + C   G+C 
Sbjct: 1358 CSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCV 1417

Query: 1086 KNGTCLCVSGWNGRHCT 1102
            +   C C+S W G +C+
Sbjct: 1418 RPNRCHCLSSWTGHNCS 1434



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 6/113 (5%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            C  +  W+     + VC   C   G C    +CSC  GW G  C   +C   C   G+C 
Sbjct: 1326 CLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCV 1385

Query: 1086 KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                C C  GW G  C    C   C   G+C   N     C C   W G +C+
Sbjct: 1386 APYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPN----RCHCLSSWTGHNCS 1434



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%)

Query: 942  CEVPDCNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEG-TCVCKKGWKGA 999
            C  P C   G C     CSC  G+ G+ C E  C  P C   G C+    C C  GW G+
Sbjct: 1342 CRFP-CQNGGICQRPNACSCPEGWMGRLCEEPICILP-CLNGGRCVAPYQCDCPPGWTGS 1399

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
             C T       C   C   G   V    C C + W+G +CS++
Sbjct: 1400 RCHT-----AVCQSPCLNGGKC-VRPNRCHCLSSWTGHNCSRK 1436



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C   C   G C   + C C  G+ G  C + +C + C   G  +   +C C PGW G  C
Sbjct: 1342 CRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRC 1401

Query: 936  SLRHDECEVPDCNGHGHCVN-GKCSCVRGYKGKFC 969
                  C+ P  NG G CV   +C C+  + G  C
Sbjct: 1402 HTA--VCQSPCLNG-GKCVRPNRCHCLSSWTGHNC 1433



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            C   C   G C+  + C C PG+ G  C  +VC   C   G+ +    C C   W G  C
Sbjct: 1374 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 1433

Query: 936  S 936
            S
Sbjct: 1434 S 1434



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            W+       +C   C   G C+    C C  GW GR C    C   C   G+C       
Sbjct: 1332 WTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAP---- 1387

Query: 1124 WECKCFDGWDGPDCTT 1139
            ++C C  GW G  C T
Sbjct: 1388 YQCDCPPGWTGSRCHT 1403


>AY916667-1|AAX12481.1| 1497|Homo sapiens CCP module-containing
            protein protein.
          Length = 1497

 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            CSC   W G  C + +C L C   GRCV    C C  GW+G  C   +C + C   G+C 
Sbjct: 1414 CSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCV 1473

Query: 1086 KNGTCLCVSGWNGRHCT 1102
            +   C C+S W G +C+
Sbjct: 1474 RPNRCHCLSSWTGHNCS 1490



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 6/113 (5%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            C  +  W+     + VC   C   G C    +CSC  GW G  C   +C   C   G+C 
Sbjct: 1382 CLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCV 1441

Query: 1086 KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                C C  GW G  C    C   C   G+C   N     C C   W G +C+
Sbjct: 1442 APYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPN----RCHCLSSWTGHNCS 1490



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%)

Query: 942  CEVPDCNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEG-TCVCKKGWKGA 999
            C  P C   G C     CSC  G+ G+ C E  C  P C   G C+    C C  GW G+
Sbjct: 1398 CRFP-CQNGGICQRPNACSCPEGWMGRLCEEPICILP-CLNGGRCVAPYQCDCPPGWTGS 1455

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
             C T       C   C   G   V    C C + W+G +CS++
Sbjct: 1456 RCHT-----AVCQSPCLNGGKC-VRPNRCHCLSSWTGHNCSRK 1492



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C   C   G C   + C C  G+ G  C + +C + C   G  +   +C C PGW G  C
Sbjct: 1398 CRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRC 1457

Query: 936  SLRHDECEVPDCNGHGHCVN-GKCSCVRGYKGKFC 969
                  C+ P  NG G CV   +C C+  + G  C
Sbjct: 1458 HTA--VCQSPCLNG-GKCVRPNRCHCLSSWTGHNC 1489



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            C   C   G C+  + C C PG+ G  C  +VC   C   G+ +    C C   W G  C
Sbjct: 1430 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 1489

Query: 936  S 936
            S
Sbjct: 1490 S 1490



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            W+       +C   C   G C+    C C  GW GR C    C   C   G+C       
Sbjct: 1388 WTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAP---- 1443

Query: 1124 WECKCFDGWDGPDCTT 1139
            ++C C  GW G  C T
Sbjct: 1444 YQCDCPPGWTGSRCHT 1459


>AL158158-6|CAI14071.1| 1497|Homo sapiens sushi, von Willebrand factor
            type A, EGF and pentraxin domain containing 1 protein.
          Length = 1497

 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            CSC   W G  C + +C L C   GRCV    C C  GW+G  C   +C + C   G+C 
Sbjct: 1414 CSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCV 1473

Query: 1086 KNGTCLCVSGWNGRHCT 1102
            +   C C+S W G +C+
Sbjct: 1474 RPNRCHCLSSWTGHNCS 1490



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 6/113 (5%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            C  +  W+     + VC   C   G C    +CSC  GW G  C   +C   C   G+C 
Sbjct: 1382 CLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCV 1441

Query: 1086 KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                C C  GW G  C    C   C   G+C   N     C C   W G +C+
Sbjct: 1442 APYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPN----RCHCLSSWTGHNCS 1490



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%)

Query: 942  CEVPDCNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEG-TCVCKKGWKGA 999
            C  P C   G C     CSC  G+ G+ C E  C  P C   G C+    C C  GW G+
Sbjct: 1398 CRFP-CQNGGICQRPNACSCPEGWMGRLCEEPICILP-CLNGGRCVAPYQCDCPPGWTGS 1455

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
             C T       C   C   G   V    C C + W+G +CS++
Sbjct: 1456 RCHT-----AVCQSPCLNGGKC-VRPNRCHCLSSWTGHNCSRK 1492



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C   C   G C   + C C  G+ G  C + +C + C   G  +   +C C PGW G  C
Sbjct: 1398 CRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRC 1457

Query: 936  SLRHDECEVPDCNGHGHCVN-GKCSCVRGYKGKFC 969
                  C+ P  NG G CV   +C C+  + G  C
Sbjct: 1458 HTA--VCQSPCLNG-GKCVRPNRCHCLSSWTGHNC 1489



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            C   C   G C+  + C C PG+ G  C  +VC   C   G+ +    C C   W G  C
Sbjct: 1430 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 1489

Query: 936  S 936
            S
Sbjct: 1490 S 1490



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            W+       +C   C   G C+    C C  GW GR C    C   C   G+C       
Sbjct: 1388 WTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAP---- 1443

Query: 1124 WECKCFDGWDGPDCTT 1139
            ++C C  GW G  C T
Sbjct: 1444 YQCDCPPGWTGSRCHT 1459


>AK075302-1|BAC11535.1|  587|Homo sapiens protein ( Homo sapiens cDNA
            FLJ90821 fis, clone Y79AA1001328, highly similar to
            Delta-like protein 3 precursor. ).
          Length = 587

 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 74/256 (28%), Positives = 102/256 (39%), Gaps = 43/256 (16%)

Query: 878  CPNGCSGK-GECLM-GHCQCQPGFGGDDCSKSVCPVLC-SQRGEYINGECQCNPGWKGKE 934
            C  GCS + G C   G C+C  G+ G  C+  V    C S RG          PG     
Sbjct: 220  CRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPG----- 274

Query: 935  CSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC--GEIDCPHPTCSGHGFCIEG 988
                   C+   C   G C       +C+C RG+ G  C    + C +  C   G C+ G
Sbjct: 275  ----PGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCANGPCFNGGLCVGG 330

Query: 989  T-------CVCKKGWKGADCGT-MDKDALQCLPDCSGHGTFDVD-TQTCSCHAKWSGEDC 1039
                    C C  G++G++C   +D+ +LQ  P  +G    D+     C C A ++G  C
Sbjct: 331  ADPDSAYICHCPPGFQGSNCEKRVDRCSLQ--PCRNGGLCLDLGHALRCRCRAGFAGPRC 388

Query: 1040 SKEV--CS-LECGPHGRCV----GESCSCAAGWSGEFCSVRL--CDAR-CAEHGQC---- 1085
              ++  C+   C   G CV       CSCA G+ G  C  R   C  R CA  G+C    
Sbjct: 389  EHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAVRPCAHGGRCYAHF 448

Query: 1086 KNGTCLCVSGWNGRHC 1101
                C C  G+ G  C
Sbjct: 449  SGLVCACAPGYMGARC 464



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 80/276 (28%), Positives = 113/276 (40%), Gaps = 58/276 (21%)

Query: 894  QCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPD-CNG--- 949
            +C+P   G  C++     LC  R    +   +C PG +   C+   DECE P  C     
Sbjct: 177  RCEPPAVGTACTR-----LCRPR----SAPSRCGPGLR--PCAPLEDECEAPPVCRAGCS 225

Query: 950  --HGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDK 1006
              HG C   G+C C+ G+ G  C     P  T S         C+  +G   A  G +  
Sbjct: 226  PEHGFCEQPGECRCLEGWTGPLC---TVPVSTSS---------CLSPRGPSSATTGCLVP 273

Query: 1007 DALQCLPD-CSGHGTFDVDTQT--CSCHAKWSGEDCSKEVCSLEC--GP---HGRCVGES 1058
                C  + C+  G+     ++  C+C   + G  C  EV  + C  GP    G CVG +
Sbjct: 274  GPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRC--EVSGVTCANGPCFNGGLCVGGA 331

Query: 1059 -------CSCAAGWSGEFCSVRL--CDAR-CAEHGQCKN-G---TCLCVSGWNGRHCT-- 1102
                   C C  G+ G  C  R+  C  + C   G C + G    C C +G+ G  C   
Sbjct: 332  DPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHD 391

Query: 1103 LEGCP-RSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            L+ C  R+CA  G C V+  G   C C  G+ G DC
Sbjct: 392  LDDCAGRACANGGTC-VEGGGAHRCSCALGFGGRDC 426



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 9/80 (11%)

Query: 1106 CPRSCAG-HGQCRVDNDGRWECKCFDGWDGPDCTT-LKEQICDDSRDNDKDGLVDC--ED 1161
            C   C+  HG C  +  G  EC+C +GW GP CT  +    C   R         C    
Sbjct: 220  CRAGCSPEHGFC--EQPG--ECRCLEGWTGPLCTVPVSTSSCLSPR-GPSSATTGCLVPG 274

Query: 1162 PECCQSPACKSSQLCVSSPK 1181
            P  C    C +   C  +P+
Sbjct: 275  PGPCDGNPCANGGSCSETPR 294


>AK075235-1|BAC11489.1| 1497|Homo sapiens protein ( Homo sapiens cDNA
            FLJ90754 fis, clone PLACE4000354, weakly similar to
            COMPLEMENT RECEPTOR TYPE 1 PRECURSOR. ).
          Length = 1497

 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            CSC   W G  C + +C L C   GRCV    C C  GW+G  C   +C + C   G+C 
Sbjct: 1414 CSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCV 1473

Query: 1086 KNGTCLCVSGWNGRHCT 1102
            +   C C+S W G +C+
Sbjct: 1474 RPNRCHCLSSWTGHNCS 1490



 Score = 71.3 bits (167), Expect = 5e-11
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 6/113 (5%)

Query: 1028 CSCHAKWSGEDCSKEVCSLECGPHGRCVG-ESCSCAAGWSGEFCSVRLCDARCAEHGQC- 1085
            C  +  W+     + VC   C   G C    +CSC  GW G  C   +C   C   G+C 
Sbjct: 1382 CLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCV 1441

Query: 1086 KNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
                C C  GW G  C    C   C   G+C   N     C C   W G +C+
Sbjct: 1442 APYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPN----RCHCLSSWTGHNCS 1490



 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 10/103 (9%)

Query: 942  CEVPDCNGHGHCVN-GKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEG-TCVCKKGWKGA 999
            C  P C   G C     CSC  G+ G+ C E  C  P C   G C+    C C  GW G+
Sbjct: 1398 CRFP-CQNGGICQRPNACSCPEGWMGRLCEEPICILP-CLNGGRCVAPYQCDCPPGWTGS 1455

Query: 1000 DCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
             C T       C   C   G   V    C C + W+G +CS++
Sbjct: 1456 RCHT-----AVCQSPCLNGGKC-VRPNRCHCLSSWTGHNCSRK 1492



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYING-ECQCNPGWKGKEC 935
            C   C   G C   + C C  G+ G  C + +C + C   G  +   +C C PGW G  C
Sbjct: 1398 CRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRC 1457

Query: 936  SLRHDECEVPDCNGHGHCVN-GKCSCVRGYKGKFC 969
                  C+ P  NG G CV   +C C+  + G  C
Sbjct: 1458 HTA--VCQSPCLNG-GKCVRPNRCHCLSSWTGHNC 1489



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 878  CPNGCSGKGECLMGH-CQCQPGFGGDDCSKSVCPVLCSQRGEYIN-GECQCNPGWKGKEC 935
            C   C   G C+  + C C PG+ G  C  +VC   C   G+ +    C C   W G  C
Sbjct: 1430 CILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNC 1489

Query: 936  S 936
            S
Sbjct: 1490 S 1490



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 5/76 (6%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKN-GTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGR 1123
            W+       +C   C   G C+    C C  GW GR C    C   C   G+C       
Sbjct: 1388 WTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAP---- 1443

Query: 1124 WECKCFDGWDGPDCTT 1139
            ++C C  GW G  C T
Sbjct: 1444 YQCDCPPGWTGSRCHT 1459


>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
            factor-beta binding protein 4L protein.
          Length = 1624

 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 98/335 (29%), Positives = 136/335 (40%), Gaps = 68/335 (20%)

Query: 902  DDCSKSVCPVLCSQRG-EYINGE--CQCNPGWKGKECSLRHDEC--EVPDCNGHGHCVNG 956
            D+C++S  P LC +   + + G   C C  G++G  C    DEC  E P C G G C N 
Sbjct: 673  DECTQS--PGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPC-GPGRCDNT 729

Query: 957  ----KCSCVRGYK----GKFCGEID-CPH--PTCSGHGFC--IEGT--CVCKKGWK---- 997
                 C+C  G++    G  C ++D C    P C+ +G C   EG+  CVC  G++    
Sbjct: 730  AGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT-YGRCENTEGSFQCVCPMGFQPNAA 788

Query: 998  GADCGTMD--KDALQCL-PDC-SGHGTFDVDTQTC-SCHAKWSGEDCSKEVCSL---ECG 1049
            G++C  +D  ++ L C   +C +  G+F    + C S H    G     + CS     CG
Sbjct: 789  GSECEDVDECENHLACPGQECVNSPGSF--QCRACPSGHHLHRGRCTDVDECSSGAPPCG 846

Query: 1050 PHGRCVGES----CSCAAGW------SGEFCSVRLC--DARCAEHGQCKNG----TCLCV 1093
            PHG C        CSCA G+       G    V  C     C  HG+C N      C C 
Sbjct: 847  PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 906

Query: 1094 SGW----NGRHC-TLEGCPRSCAGHGQCRVDNDGRWECKCFDGW-DGPDCTTLKEQICDD 1147
             G+     G  C  ++ C            + DG +EC C  G   GPD  +     C D
Sbjct: 907  PGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLAS-----CLD 961

Query: 1148 SRDNDKDGLVDCEDPECCQSPACKSSQLCVSSPKP 1182
              +  + G   C    C  SP    S  CV    P
Sbjct: 962  VDECRERGPALCGSQRCENSP---GSYRCVRDCDP 993



 Score = 38.3 bits (85), Expect = 0.42
 Identities = 67/267 (25%), Positives = 100/267 (37%), Gaps = 37/267 (13%)

Query: 945  PDCNGHGHCVNGK----CSCVRGYK----GKFCGEID-C---PHPTCSGHGFCIEGT--C 990
            P   G G C++      C+C  G++    G  C ++D C   P P   G      G+  C
Sbjct: 553  PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRC 612

Query: 991  VCKKGWKG----ADCGTMDKDALQCLPDCS-GHGTFDVDTQTCSCHAKWS----GEDCSK 1041
            VC  G++     A+C  +D +  +  P C  G       +  C C A +     G  C  
Sbjct: 613  VCGPGFRAGPRAAECLDVD-ECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 671

Query: 1042 -EVCSLECGPHGRCVGES------CSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVS 1094
             + C+   G  GR   ++      C C AG+ G  C   + D    E   C  G C   +
Sbjct: 672  VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV-DECAQEPPPCGPGRCDNTA 730

Query: 1095 GWNGRHCTLEGCPRSCAGHGQCR-VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDK 1153
            G    HC      RS      C+ VD   R    C  G    +     + +C      + 
Sbjct: 731  G--SFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNA 787

Query: 1154 DGLVDCEDPECCQSPACKSSQLCVSSP 1180
             G  +CED + C++      Q CV+SP
Sbjct: 788  AGS-ECEDVDECENHLACPGQECVNSP 813



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 43/134 (32%), Positives = 64/134 (47%), Gaps = 25/134 (18%)

Query: 902  DDCSKSVCPVLC-SQRGEYINGE--C--QCNPGWK-GKECSLRH-DECEV--PDCNGHGH 952
            D+C +   P LC SQR E   G   C   C+PG+  G E +    DEC+   P+  G   
Sbjct: 963  DECRERG-PALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR 1021

Query: 953  CVNG----KCS--CVRGYK---GKFCGEID-CPHPT-CSGHGFC--IEGT--CVCKKGWK 997
            C N     +C+  C  GY+   G  C ++D C + + C  H  C  + G+  C+C +G++
Sbjct: 1022 CENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYE 1081

Query: 998  GADCGTMDKDALQC 1011
            GA  G    D  +C
Sbjct: 1082 GARDGRHCVDVNEC 1095


>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
            factor-beta binding protein 4S protein.
          Length = 1557

 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 98/335 (29%), Positives = 136/335 (40%), Gaps = 68/335 (20%)

Query: 902  DDCSKSVCPVLCSQRG-EYINGE--CQCNPGWKGKECSLRHDEC--EVPDCNGHGHCVNG 956
            D+C++S  P LC +   + + G   C C  G++G  C    DEC  E P C G G C N 
Sbjct: 606  DECTQS--PGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPC-GPGRCDNT 662

Query: 957  ----KCSCVRGYK----GKFCGEID-CPH--PTCSGHGFC--IEGT--CVCKKGWK---- 997
                 C+C  G++    G  C ++D C    P C+ +G C   EG+  CVC  G++    
Sbjct: 663  AGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT-YGRCENTEGSFQCVCPMGFQPNAA 721

Query: 998  GADCGTMD--KDALQCL-PDC-SGHGTFDVDTQTC-SCHAKWSGEDCSKEVCSL---ECG 1049
            G++C  +D  ++ L C   +C +  G+F    + C S H    G     + CS     CG
Sbjct: 722  GSECEDVDECENHLACPGQECVNSPGSF--QCRACPSGHHLHRGRCTDVDECSSGAPPCG 779

Query: 1050 PHGRCVGES----CSCAAGW------SGEFCSVRLC--DARCAEHGQCKNG----TCLCV 1093
            PHG C        CSCA G+       G    V  C     C  HG+C N      C C 
Sbjct: 780  PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 839

Query: 1094 SGW----NGRHC-TLEGCPRSCAGHGQCRVDNDGRWECKCFDGW-DGPDCTTLKEQICDD 1147
             G+     G  C  ++ C            + DG +EC C  G   GPD  +     C D
Sbjct: 840  PGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLAS-----CLD 894

Query: 1148 SRDNDKDGLVDCEDPECCQSPACKSSQLCVSSPKP 1182
              +  + G   C    C  SP    S  CV    P
Sbjct: 895  VDECRERGPALCGSQRCENSP---GSYRCVRDCDP 926



 Score = 38.3 bits (85), Expect = 0.42
 Identities = 67/267 (25%), Positives = 100/267 (37%), Gaps = 37/267 (13%)

Query: 945  PDCNGHGHCVNGK----CSCVRGYK----GKFCGEID-C---PHPTCSGHGFCIEGT--C 990
            P   G G C++      C+C  G++    G  C ++D C   P P   G      G+  C
Sbjct: 486  PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRC 545

Query: 991  VCKKGWKG----ADCGTMDKDALQCLPDCS-GHGTFDVDTQTCSCHAKWS----GEDCSK 1041
            VC  G++     A+C  +D +  +  P C  G       +  C C A +     G  C  
Sbjct: 546  VCGPGFRAGPRAAECLDVD-ECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 604

Query: 1042 -EVCSLECGPHGRCVGES------CSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVS 1094
             + C+   G  GR   ++      C C AG+ G  C   + D    E   C  G C   +
Sbjct: 605  VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDV-DECAQEPPPCGPGRCDNTA 663

Query: 1095 GWNGRHCTLEGCPRSCAGHGQCR-VDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDK 1153
            G    HC      RS      C+ VD   R    C  G    +     + +C      + 
Sbjct: 664  G--SFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNA 720

Query: 1154 DGLVDCEDPECCQSPACKSSQLCVSSP 1180
             G  +CED + C++      Q CV+SP
Sbjct: 721  AGS-ECEDVDECENHLACPGQECVNSP 746



 Score = 37.1 bits (82), Expect = 0.97
 Identities = 43/134 (32%), Positives = 64/134 (47%), Gaps = 25/134 (18%)

Query: 902  DDCSKSVCPVLC-SQRGEYINGE--C--QCNPGWK-GKECSLRH-DECEV--PDCNGHGH 952
            D+C +   P LC SQR E   G   C   C+PG+  G E +    DEC+   P+  G   
Sbjct: 896  DECRERG-PALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR 954

Query: 953  CVNG----KCS--CVRGYK---GKFCGEID-CPHPT-CSGHGFC--IEGT--CVCKKGWK 997
            C N     +C+  C  GY+   G  C ++D C + + C  H  C  + G+  C+C +G++
Sbjct: 955  CENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYE 1014

Query: 998  GADCGTMDKDALQC 1011
            GA  G    D  +C
Sbjct: 1015 GARDGRHCVDVNEC 1028


>AB052957-1|BAC15607.1|  803|Homo sapiens soluble form FELE-1 protein.
          Length = 803

 Score = 74.5 bits (175), Expect = 5e-12
 Identities = 63/207 (30%), Positives = 91/207 (43%), Gaps = 43/207 (20%)

Query: 959  SCVRGYKGKFCGEIDCP---HPTCSGHGFCIEG-----TCVCKKGWKGADCGTMDKDALQ 1010
            +C  GY G  C E  CP      C+GHG C++G     TCVC++ ++G+ C    +D  +
Sbjct: 99   ACCPGYWGSRCHE--CPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQEC-QDPNR 155

Query: 1011 CLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFC 1070
              PDC            CSC            VC+   GP G     SC C AG++G  C
Sbjct: 156  FGPDCQS---------VCSC---------VHGVCNH--GPRG---DGSCLCFAGYTGPHC 192

Query: 1071 SVRL--C-DARCAEHGQC--KNGTCLCVSGWN--GRHCTLEG-C-PRSCAGHGQCRVDND 1121
               L  C + RC ++ QC  +  +C C+ G+   G  C     C P  C+   QC V   
Sbjct: 193  DQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPK 252

Query: 1122 GRWECKCFDGWDGPDCTTLKEQICDDS 1148
            G+ +C C + + G     L +  C D+
Sbjct: 253  GQAQCHCPENYHGDGMVCLPKDPCTDN 279



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 85/313 (27%), Positives = 122/313 (38%), Gaps = 65/313 (20%)

Query: 878  CPNGCSGK-GECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECS 936
            CP+G   +  + +   C+ +   GG   S S C   C  R + +   C C PG+ G  C 
Sbjct: 55   CPSGWLRELPDQITQDCRYEVQLGGSMVSMSGCRRKC--RKQVVQKAC-C-PGYWGSRCH 110

Query: 937  LRHDECEVPDCNGHGHCV-----NGKCSCVRGYKGKFCGEIDCPH---PTCSG-----HG 983
                  E P CNGHG C+     NG C C   ++G  C E   P+   P C       HG
Sbjct: 111  ECPGGAETP-CNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG 169

Query: 984  FCI-----EGTCVCKKGWKGADCGTMDKDALQCLP-DCSGHGTFDVDTQTCSCHAKWS-- 1035
             C      +G+C+C  G+ G  C   D++   C    C  +     +  +C C   ++  
Sbjct: 170  VCNHGPRGDGSCLCFAGYTGPHC---DQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQ 226

Query: 1036 GEDCSK------EVCSL--ECG--PHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH-GQ 1084
            G +C          CSL  +C   P G+     C C   + G+   V L    C ++ G 
Sbjct: 227  GSECRAPNPCWPSPCSLLAQCSVSPKGQA---QCHCPENYHGDGM-VCLPKDPCTDNLGG 282

Query: 1085 CKNGTCLCVSGWNGR-HCTLE------------GC-----PRSCAGHGQCRVDNDGRWEC 1126
            C + + LCV    G+  CT              GC     P SC     C+V  DG+  C
Sbjct: 283  CPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFCSPFSCDRSATCQVTADGKTSC 342

Query: 1127 KCFDG--WDGPDC 1137
             C +    DG  C
Sbjct: 343  VCRESEVGDGRAC 355



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 44/164 (26%), Positives = 56/164 (34%), Gaps = 27/164 (16%)

Query: 876  HNCPNG----CSGKGECL-----MGHCQCQPGFGGDDCSKSV--------CPVLCS---- 914
            H CP G    C+G G CL      G C CQ  F G  C +          C  +CS    
Sbjct: 110  HECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQECQDPNRFGPDCQSVCSCVHG 169

Query: 915  --QRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHC--VNGKCSCVRGYKGKFCG 970
                G   +G C C  G+ G  C      C+   C  +  C      C C+ GY  +   
Sbjct: 170  VCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQ-GS 228

Query: 971  EIDCPHPTCSGHGFCIEGTCVCKKGWKGADC-GTMDKDALQCLP 1013
            E   P+P        +    V  KG     C      D + CLP
Sbjct: 229  ECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGMVCLP 272



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 32/125 (25%), Positives = 40/125 (32%), Gaps = 11/125 (8%)

Query: 1055 VGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGR-HCTLEGCPRSCAGH 1113
            + + C       G   S+  C  +C +  Q     C C   W  R H    G    C GH
Sbjct: 67   ITQDCRYEVQLGGSMVSMSGCRRKCRK--QVVQKAC-CPGYWGSRCHECPGGAETPCNGH 123

Query: 1114 GQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSR--DNDKDGLVDCEDPECCQSPACK 1171
            G C    D    C C + + G  C     Q C D      D   +  C    C   P   
Sbjct: 124  GTCLDGMDRNGTCVCQENFRGSAC-----QECQDPNRFGPDCQSVCSCVHGVCNHGPRGD 178

Query: 1172 SSQLC 1176
             S LC
Sbjct: 179  GSCLC 183


>AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1
            (Drosophila) protein.
          Length = 1294

 Score = 74.1 bits (174), Expect = 7e-12
 Identities = 77/307 (25%), Positives = 115/307 (37%), Gaps = 52/307 (16%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGG--DDCSKSVCPVL---CSQRGEYIN--GE--- 923
            ++++C N  + K       C C         DC     P     C      +N  GE   
Sbjct: 35   LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94

Query: 924  -CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEID---CP 975
             C+C PG+ G  C      C    C   G C    +   C C  GY G+FC EID   C 
Sbjct: 95   LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-EIDHDECA 153

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTC 1028
               C     C +G    +C C  G++G  C   D +  +C  D C    T   ++   TC
Sbjct: 154  SSPCQNGAVCQDGIDGYSCFCVPGYQGRHC---DLEVDECASDPCKNEATCLNEIGRYTC 210

Query: 1029 SC---HAKWSGEDCS---KEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH 1082
             C   ++ ++G  C     E  S  C  +G CV  S         ++  +    +  + H
Sbjct: 211  ICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSS------EKQYGRITGLPSSFSYH 264

Query: 1083 GQCKNGTCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKC-FDG-----WD 1133
             +     C+C  G+ G HC   +  C  + C   G C  +  G + C C FD      + 
Sbjct: 265  -EASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCE-NLPGNYTCHCPFDNLSRTFYG 322

Query: 1134 GPDCTTL 1140
            G DC+ +
Sbjct: 323  GRDCSDI 329



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 55/183 (30%), Positives = 75/183 (40%), Gaps = 27/183 (14%)

Query: 919  YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID- 973
            Y +  C C  GW GK C L  DEC    C  HG+C +      C+C  GY G  C E+D 
Sbjct: 1046 YSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCTCEPGYTGVNC-EVDI 1103

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC------LPDCSGHGTF 1021
              C    C+    CI  T    C+C   + G  C      +  C      L   +G    
Sbjct: 1104 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1163

Query: 1022 DVDTQ-TCSCHAKWSGEDCSKEV--CSLE-CGPHGRCVG----ESCSCAAGWSGEFCSVR 1073
            +  T+  C C   ++GE C K++  C+ + C   G C        C C   ++GE C V 
Sbjct: 1164 EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1223

Query: 1074 LCD 1076
            L D
Sbjct: 1224 LAD 1226



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 74/272 (27%), Positives = 109/272 (40%), Gaps = 76/272 (27%)

Query: 870  VAEEMTHNC-PNGCSGKGEC----LMGHCQCQPGFGG-------DDCSKSVCP--VLCSQ 915
            + E    +C  N C   G C    +   C C  G+ G       D+C+ S C    +C Q
Sbjct: 106  ICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-Q 164

Query: 916  RGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GKCSCV-----RGYKGK 967
             G  I+G  C C PG++G+ C L  DEC    C     C+N  G+ +C+      GY G 
Sbjct: 165  DG--IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGA 222

Query: 968  FCGEID---CPHPTCSGHGFCIE------------------------GTCVCKKGWKGAD 1000
             C EID   C    C  +G C+E                          C+C+ G+ G  
Sbjct: 223  QC-EIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIH 281

Query: 1001 CGTMDKDALQCLPD-CSGHGTFD--VDTQTCSC------HAKWSGEDCSKEV--CS-LEC 1048
            C   ++D  +C  + C   GT +      TC C         + G DCS  +  C+  +C
Sbjct: 282  C---EEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQC 338

Query: 1049 GPHGRCV--------GESCSCAAGWSGEFCSV 1072
              +G C+        G SC C +G++G  C +
Sbjct: 339  LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 370



 Score = 61.3 bits (142), Expect = 5e-08
 Identities = 58/206 (28%), Positives = 80/206 (38%), Gaps = 37/206 (17%)

Query: 965  KGKFCGEID--CPHPTCSGHGFCIE----GTCVCKKGWKGAD--CGTMDKDALQCLPDCS 1016
            K  FC + +  C   +C  +  C +      C C       D  C  M KD     P C 
Sbjct: 23   KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNM-KDPCFSNP-CQ 80

Query: 1017 GHGTFDVDTQ-----TCSCHAKWSGEDCSKEVCSL---ECGPHGRC----VGESCSCAAG 1064
            G  T  V+T       C C   +SG  C   + S     C   G C    +   C C AG
Sbjct: 81   GSATC-VNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAG 139

Query: 1065 WSGEFCSV---RLCDARCAEHGQCKNG----TCLCVSGWNGRHCTLE--GCPRS-CAGHG 1114
            ++G FC +       + C     C++G    +C CV G+ GRHC LE   C    C    
Sbjct: 140  YAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEA 199

Query: 1115 QCRVDNDGRWECKC---FDGWDGPDC 1137
             C ++  GR+ C C   + G+ G  C
Sbjct: 200  TC-LNEIGRYTCICPHNYSGYTGAQC 224



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 1059 CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT----CLCVSGWNGRHCT--LEGCPRSC 1110
            CSC  GWSG+ C + +  C +    HG C +      C C  G+ G +C   ++ C    
Sbjct: 1051 CSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ 1110

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC--TTLKEQICDDSRDN 1151
              +G   + +   + C CF  + G  C  + L   +C + + N
Sbjct: 1111 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1153



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 8/73 (10%)

Query: 1072 VRLCDAR-CAEHGQCKN----GTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDGRW 1124
            + +C++  C   G C++      C C  GW+G+HC L  + C  +   HG C  D    +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS-DRVAAY 1086

Query: 1125 ECKCFDGWDGPDC 1137
             C C  G+ G +C
Sbjct: 1087 HCTCEPGYTGVNC 1099



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 24/134 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKEC-------SL 937
            HC C+PG+ G +C   +  C       G     + NG  C C   + GK C       ++
Sbjct: 1087 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1146

Query: 938  RHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPHPTCSGHGFCIE---- 987
              +E     C   G+C       KC C  G+ G++C  +ID C    C   G C +    
Sbjct: 1147 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1206

Query: 988  GTCVCKKGWKGADC 1001
              C+C   + G  C
Sbjct: 1207 FQCLCDVAFAGERC 1220


>AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1
            (Drosophila) protein.
          Length = 1294

 Score = 74.1 bits (174), Expect = 7e-12
 Identities = 77/307 (25%), Positives = 115/307 (37%), Gaps = 52/307 (16%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGG--DDCSKSVCPVL---CSQRGEYIN--GE--- 923
            ++++C N  + K       C C         DC     P     C      +N  GE   
Sbjct: 35   LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94

Query: 924  -CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEID---CP 975
             C+C PG+ G  C      C    C   G C    +   C C  GY G+FC EID   C 
Sbjct: 95   LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-EIDHDECA 153

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTC 1028
               C     C +G    +C C  G++G  C   D +  +C  D C    T   ++   TC
Sbjct: 154  SSPCQNGAVCQDGIDGYSCFCVPGYQGRHC---DLEVDECASDPCKNEATCLNEIGRYTC 210

Query: 1029 SC---HAKWSGEDCS---KEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH 1082
             C   ++ ++G  C     E  S  C  +G CV  S         ++  +    +  + H
Sbjct: 211  ICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSS------EKQYGRITGLPSSFSYH 264

Query: 1083 GQCKNGTCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKC-FDG-----WD 1133
             +     C+C  G+ G HC   +  C  + C   G C  +  G + C C FD      + 
Sbjct: 265  -EASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCE-NLPGNYTCHCPFDNLSRTFYG 322

Query: 1134 GPDCTTL 1140
            G DC+ +
Sbjct: 323  GRDCSDI 329



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 55/183 (30%), Positives = 75/183 (40%), Gaps = 27/183 (14%)

Query: 919  YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID- 973
            Y +  C C  GW GK C L  DEC    C  HG+C +      C+C  GY G  C E+D 
Sbjct: 1046 YSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCTCEPGYTGVNC-EVDI 1103

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC------LPDCSGHGTF 1021
              C    C+    CI  T    C+C   + G  C      +  C      L   +G    
Sbjct: 1104 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1163

Query: 1022 DVDTQ-TCSCHAKWSGEDCSKEV--CSLE-CGPHGRCVG----ESCSCAAGWSGEFCSVR 1073
            +  T+  C C   ++GE C K++  C+ + C   G C        C C   ++GE C V 
Sbjct: 1164 EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1223

Query: 1074 LCD 1076
            L D
Sbjct: 1224 LAD 1226



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 74/272 (27%), Positives = 109/272 (40%), Gaps = 76/272 (27%)

Query: 870  VAEEMTHNC-PNGCSGKGEC----LMGHCQCQPGFGG-------DDCSKSVCP--VLCSQ 915
            + E    +C  N C   G C    +   C C  G+ G       D+C+ S C    +C Q
Sbjct: 106  ICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-Q 164

Query: 916  RGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GKCSCV-----RGYKGK 967
             G  I+G  C C PG++G+ C L  DEC    C     C+N  G+ +C+      GY G 
Sbjct: 165  DG--IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGA 222

Query: 968  FCGEID---CPHPTCSGHGFCIE------------------------GTCVCKKGWKGAD 1000
             C EID   C    C  +G C+E                          C+C+ G+ G  
Sbjct: 223  QC-EIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIH 281

Query: 1001 CGTMDKDALQCLPD-CSGHGTFD--VDTQTCSC------HAKWSGEDCSKEV--CS-LEC 1048
            C   ++D  +C  + C   GT +      TC C         + G DCS  +  C+  +C
Sbjct: 282  C---EEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQC 338

Query: 1049 GPHGRCV--------GESCSCAAGWSGEFCSV 1072
              +G C+        G SC C +G++G  C +
Sbjct: 339  LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 370



 Score = 61.3 bits (142), Expect = 5e-08
 Identities = 58/206 (28%), Positives = 80/206 (38%), Gaps = 37/206 (17%)

Query: 965  KGKFCGEID--CPHPTCSGHGFCIE----GTCVCKKGWKGAD--CGTMDKDALQCLPDCS 1016
            K  FC + +  C   +C  +  C +      C C       D  C  M KD     P C 
Sbjct: 23   KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNM-KDPCFSNP-CQ 80

Query: 1017 GHGTFDVDTQ-----TCSCHAKWSGEDCSKEVCSL---ECGPHGRC----VGESCSCAAG 1064
            G  T  V+T       C C   +SG  C   + S     C   G C    +   C C AG
Sbjct: 81   GSATC-VNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAG 139

Query: 1065 WSGEFCSV---RLCDARCAEHGQCKNG----TCLCVSGWNGRHCTLE--GCPRS-CAGHG 1114
            ++G FC +       + C     C++G    +C CV G+ GRHC LE   C    C    
Sbjct: 140  YAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEA 199

Query: 1115 QCRVDNDGRWECKC---FDGWDGPDC 1137
             C ++  GR+ C C   + G+ G  C
Sbjct: 200  TC-LNEIGRYTCICPHNYSGYTGAQC 224



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 1059 CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT----CLCVSGWNGRHCT--LEGCPRSC 1110
            CSC  GWSG+ C + +  C +    HG C +      C C  G+ G +C   ++ C    
Sbjct: 1051 CSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ 1110

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC--TTLKEQICDDSRDN 1151
              +G   + +   + C CF  + G  C  + L   +C + + N
Sbjct: 1111 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1153



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 8/73 (10%)

Query: 1072 VRLCDAR-CAEHGQCKN----GTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDGRW 1124
            + +C++  C   G C++      C C  GW+G+HC L  + C  +   HG C  D    +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS-DRVAAY 1086

Query: 1125 ECKCFDGWDGPDC 1137
             C C  G+ G +C
Sbjct: 1087 HCTCEPGYTGVNC 1099



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 24/134 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKEC-------SL 937
            HC C+PG+ G +C   +  C       G     + NG  C C   + GK C       ++
Sbjct: 1087 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1146

Query: 938  RHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPHPTCSGHGFCIE---- 987
              +E     C   G+C       KC C  G+ G++C  +ID C    C   G C +    
Sbjct: 1147 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1206

Query: 988  GTCVCKKGWKGADC 1001
              C+C   + G  C
Sbjct: 1207 FQCLCDVAFAGERC 1220


>AL137007-1|CAC10575.2|  199|Homo sapiens novel EGF-like domain
            containing protein protein.
          Length = 199

 Score = 74.1 bits (174), Expect = 7e-12
 Identities = 58/202 (28%), Positives = 86/202 (42%), Gaps = 33/202 (16%)

Query: 924  CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGK--CSCVRGYKGKFCGE----ID 973
            C+C  GW G+ CS   +EC+   C   G C    + G+  C C   Y G+FC +     D
Sbjct: 1    CECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD 60

Query: 974  CPHPTCSGHGFCI-----EGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTC 1028
              H  C  +  C+        C+C++ ++G +C    KD L     C  +G  D +    
Sbjct: 61   LLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCL--FLSCQDYG--DCEDMVN 116

Query: 1029 SCHAKWSGEDCSKEV--CSLE-CGPHGRCVGES----CSCAAGWSGEFC--SVRLCD-AR 1078
            +    +SG  C  E+  CS E C  +G CV  +    C+C   + G FC   V  C  + 
Sbjct: 117  NFRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISP 176

Query: 1079 CAEHGQCKNGT----CLCVSGW 1096
            C +   C   T    CLC  G+
Sbjct: 177  CLDEENCVYRTDGYNCLCAPGY 198



 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 55/203 (27%), Positives = 92/203 (45%), Gaps = 33/203 (16%)

Query: 893  CQCQPGFGGDDCSKSV--CPV-LCSQRG----EYINGE--CQCNPGWKGKECSLRHDECE 943
            C+C  G+ G +CS+ +  C    C   G      I G+  C C P + G+ C  R++ C+
Sbjct: 1    CECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD 60

Query: 944  V--PDCNGHGHCV-----NGKCSCVRGYKGKFCGEI---DCPHPTCSGHGFCIEGTCVCK 993
            +    C  +  C+     N  C C   ++GK C EI   DC   +C  +G C +     +
Sbjct: 61   LLHNPCRNNSTCLALVDANQHCICREEFEGKNC-EIDVKDCLFLSCQDYGDCEDMVNNFR 119

Query: 994  KGWKGADCGTMDKDALQCLPD-CSGHGT-FDVDTQ-TCSCHAKWSGEDCSKEV--CSLE- 1047
             G+ G+ C   + +  +C  + C  +GT  D+  +  C+C  ++ G  C  +V  C +  
Sbjct: 120  PGFSGSLC---EIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISP 176

Query: 1048 CGPHGRCV----GESCSCAAGWS 1066
            C     CV    G +C CA G++
Sbjct: 177  CLDEENCVYRTDGYNCLCAPGYT 199



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 41/166 (24%), Positives = 68/166 (40%), Gaps = 19/166 (11%)

Query: 990  CVCKKGWKGADCGTM--DKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE--VCS 1045
            C C  GW G +C     + D+  C+     H +       C C   ++G+ C +   +C 
Sbjct: 1    CECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD 60

Query: 1046 L---ECGPHGRCVG-----ESCSCAAGWSGEFCSVRLCDA---RCAEHGQCKNGTCLCVS 1094
            L    C  +  C+      + C C   + G+ C + + D     C ++G C++       
Sbjct: 61   LLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRP 120

Query: 1095 GWNGRHCTLE--GCPRS-CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            G++G  C +E   C    C  +G C VD   R+ C C   + GP C
Sbjct: 121  GFSGSLCEIEINECSSEPCKNNGTC-VDLTNRFFCNCEPEYHGPFC 165


>AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1
            (Drosophila) protein.
          Length = 1294

 Score = 74.1 bits (174), Expect = 7e-12
 Identities = 77/307 (25%), Positives = 115/307 (37%), Gaps = 52/307 (16%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGG--DDCSKSVCPVL---CSQRGEYIN--GE--- 923
            ++++C N  + K       C C         DC     P     C      +N  GE   
Sbjct: 35   LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94

Query: 924  -CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEID---CP 975
             C+C PG+ G  C      C    C   G C    +   C C  GY G+FC EID   C 
Sbjct: 95   LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-EIDHDECA 153

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTC 1028
               C     C +G    +C C  G++G  C   D +  +C  D C    T   ++   TC
Sbjct: 154  SSPCQNGAVCQDGIDGYSCFCVPGYQGRHC---DLEVDECASDPCKNEATCLNEIGRYTC 210

Query: 1029 SC---HAKWSGEDCS---KEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH 1082
             C   ++ ++G  C     E  S  C  +G CV  S         ++  +    +  + H
Sbjct: 211  ICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSS------EKQYGRITGLPSSFSYH 264

Query: 1083 GQCKNGTCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKC-FDG-----WD 1133
             +     C+C  G+ G HC   +  C  + C   G C  +  G + C C FD      + 
Sbjct: 265  -EASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCE-NLPGNYTCHCPFDNLSRTFYG 322

Query: 1134 GPDCTTL 1140
            G DC+ +
Sbjct: 323  GRDCSDI 329



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 55/183 (30%), Positives = 75/183 (40%), Gaps = 27/183 (14%)

Query: 919  YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID- 973
            Y +  C C  GW GK C L  DEC    C  HG+C +      C+C  GY G  C E+D 
Sbjct: 1046 YSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCTCEPGYTGVNC-EVDI 1103

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC------LPDCSGHGTF 1021
              C    C+    CI  T    C+C   + G  C      +  C      L   +G    
Sbjct: 1104 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1163

Query: 1022 DVDTQ-TCSCHAKWSGEDCSKEV--CSLE-CGPHGRCVG----ESCSCAAGWSGEFCSVR 1073
            +  T+  C C   ++GE C K++  C+ + C   G C        C C   ++GE C V 
Sbjct: 1164 EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1223

Query: 1074 LCD 1076
            L D
Sbjct: 1224 LAD 1226



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 74/272 (27%), Positives = 109/272 (40%), Gaps = 76/272 (27%)

Query: 870  VAEEMTHNC-PNGCSGKGEC----LMGHCQCQPGFGG-------DDCSKSVCP--VLCSQ 915
            + E    +C  N C   G C    +   C C  G+ G       D+C+ S C    +C Q
Sbjct: 106  ICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-Q 164

Query: 916  RGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GKCSCV-----RGYKGK 967
             G  I+G  C C PG++G+ C L  DEC    C     C+N  G+ +C+      GY G 
Sbjct: 165  DG--IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGA 222

Query: 968  FCGEID---CPHPTCSGHGFCIE------------------------GTCVCKKGWKGAD 1000
             C EID   C    C  +G C+E                          C+C+ G+ G  
Sbjct: 223  QC-EIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIH 281

Query: 1001 CGTMDKDALQCLPD-CSGHGTFD--VDTQTCSC------HAKWSGEDCSKEV--CS-LEC 1048
            C   ++D  +C  + C   GT +      TC C         + G DCS  +  C+  +C
Sbjct: 282  C---EEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQC 338

Query: 1049 GPHGRCV--------GESCSCAAGWSGEFCSV 1072
              +G C+        G SC C +G++G  C +
Sbjct: 339  LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 370



 Score = 61.3 bits (142), Expect = 5e-08
 Identities = 58/206 (28%), Positives = 80/206 (38%), Gaps = 37/206 (17%)

Query: 965  KGKFCGEID--CPHPTCSGHGFCIE----GTCVCKKGWKGAD--CGTMDKDALQCLPDCS 1016
            K  FC + +  C   +C  +  C +      C C       D  C  M KD     P C 
Sbjct: 23   KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNM-KDPCFSNP-CQ 80

Query: 1017 GHGTFDVDTQ-----TCSCHAKWSGEDCSKEVCSL---ECGPHGRC----VGESCSCAAG 1064
            G  T  V+T       C C   +SG  C   + S     C   G C    +   C C AG
Sbjct: 81   GSATC-VNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAG 139

Query: 1065 WSGEFCSV---RLCDARCAEHGQCKNG----TCLCVSGWNGRHCTLE--GCPRS-CAGHG 1114
            ++G FC +       + C     C++G    +C CV G+ GRHC LE   C    C    
Sbjct: 140  YAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEA 199

Query: 1115 QCRVDNDGRWECKC---FDGWDGPDC 1137
             C ++  GR+ C C   + G+ G  C
Sbjct: 200  TC-LNEIGRYTCICPHNYSGYTGAQC 224



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 1059 CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT----CLCVSGWNGRHCT--LEGCPRSC 1110
            CSC  GWSG+ C + +  C +    HG C +      C C  G+ G +C   ++ C    
Sbjct: 1051 CSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ 1110

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC--TTLKEQICDDSRDN 1151
              +G   + +   + C CF  + G  C  + L   +C + + N
Sbjct: 1111 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1153



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 8/73 (10%)

Query: 1072 VRLCDAR-CAEHGQCKN----GTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDGRW 1124
            + +C++  C   G C++      C C  GW+G+HC L  + C  +   HG C  D    +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS-DRVAAY 1086

Query: 1125 ECKCFDGWDGPDC 1137
             C C  G+ G +C
Sbjct: 1087 HCTCEPGYTGVNC 1099



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 24/134 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKEC-------SL 937
            HC C+PG+ G +C   +  C       G     + NG  C C   + GK C       ++
Sbjct: 1087 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1146

Query: 938  RHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPHPTCSGHGFCIE---- 987
              +E     C   G+C       KC C  G+ G++C  +ID C    C   G C +    
Sbjct: 1147 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1206

Query: 988  GTCVCKKGWKGADC 1001
              C+C   + G  C
Sbjct: 1207 FQCLCDVAFAGERC 1220


>AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1
            (alternative protein) protein.
          Length = 1294

 Score = 74.1 bits (174), Expect = 7e-12
 Identities = 77/307 (25%), Positives = 115/307 (37%), Gaps = 52/307 (16%)

Query: 874  MTHNCPNGCSGKGECLMGHCQCQPGFGG--DDCSKSVCPVL---CSQRGEYIN--GE--- 923
            ++++C N  + K       C C         DC     P     C      +N  GE   
Sbjct: 35   LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF 94

Query: 924  -CQCNPGWKGKECSLRHDECEVPDCNGHGHC----VNGKCSCVRGYKGKFCGEID---CP 975
             C+C PG+ G  C      C    C   G C    +   C C  GY G+FC EID   C 
Sbjct: 95   LCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC-EIDHDECA 153

Query: 976  HPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD-CSGHGTF--DVDTQTC 1028
               C     C +G    +C C  G++G  C   D +  +C  D C    T   ++   TC
Sbjct: 154  SSPCQNGAVCQDGIDGYSCFCVPGYQGRHC---DLEVDECASDPCKNEATCLNEIGRYTC 210

Query: 1029 SC---HAKWSGEDCS---KEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEH 1082
             C   ++ ++G  C     E  S  C  +G CV  S         ++  +    +  + H
Sbjct: 211  ICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSS------EKQYGRITGLPSSFSYH 264

Query: 1083 GQCKNGTCLCVSGWNGRHC--TLEGCPRS-CAGHGQCRVDNDGRWECKC-FDG-----WD 1133
             +     C+C  G+ G HC   +  C  + C   G C  +  G + C C FD      + 
Sbjct: 265  -EASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCE-NLPGNYTCHCPFDNLSRTFYG 322

Query: 1134 GPDCTTL 1140
            G DC+ +
Sbjct: 323  GRDCSDI 329



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 55/183 (30%), Positives = 75/183 (40%), Gaps = 27/183 (14%)

Query: 919  YINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEID- 973
            Y +  C C  GW GK C L  DEC    C  HG+C +      C+C  GY G  C E+D 
Sbjct: 1046 YSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCTCEPGYTGVNC-EVDI 1103

Query: 974  --CPHPTCSGHGFCIEGT----CVCKKGWKGADCGTMDKDALQC------LPDCSGHGTF 1021
              C    C+    CI  T    C+C   + G  C      +  C      L   +G    
Sbjct: 1104 DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCT 1163

Query: 1022 DVDTQ-TCSCHAKWSGEDCSKEV--CSLE-CGPHGRCVG----ESCSCAAGWSGEFCSVR 1073
            +  T+  C C   ++GE C K++  C+ + C   G C        C C   ++GE C V 
Sbjct: 1164 EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVD 1223

Query: 1074 LCD 1076
            L D
Sbjct: 1224 LAD 1226



 Score = 67.3 bits (157), Expect = 8e-10
 Identities = 74/272 (27%), Positives = 109/272 (40%), Gaps = 76/272 (27%)

Query: 870  VAEEMTHNC-PNGCSGKGEC----LMGHCQCQPGFGG-------DDCSKSVCP--VLCSQ 915
            + E    +C  N C   G C    +   C C  G+ G       D+C+ S C    +C Q
Sbjct: 106  ICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVC-Q 164

Query: 916  RGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVN--GKCSCV-----RGYKGK 967
             G  I+G  C C PG++G+ C L  DEC    C     C+N  G+ +C+      GY G 
Sbjct: 165  DG--IDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGYTGA 222

Query: 968  FCGEID---CPHPTCSGHGFCIE------------------------GTCVCKKGWKGAD 1000
             C EID   C    C  +G C+E                          C+C+ G+ G  
Sbjct: 223  QC-EIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIH 281

Query: 1001 CGTMDKDALQCLPD-CSGHGTFD--VDTQTCSC------HAKWSGEDCSKEV--CS-LEC 1048
            C   ++D  +C  + C   GT +      TC C         + G DCS  +  C+  +C
Sbjct: 282  C---EEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQC 338

Query: 1049 GPHGRCV--------GESCSCAAGWSGEFCSV 1072
              +G C+        G SC C +G++G  C +
Sbjct: 339  LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 370



 Score = 61.3 bits (142), Expect = 5e-08
 Identities = 58/206 (28%), Positives = 80/206 (38%), Gaps = 37/206 (17%)

Query: 965  KGKFCGEID--CPHPTCSGHGFCIE----GTCVCKKGWKGAD--CGTMDKDALQCLPDCS 1016
            K  FC + +  C   +C  +  C +      C C       D  C  M KD     P C 
Sbjct: 23   KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNM-KDPCFSNP-CQ 80

Query: 1017 GHGTFDVDTQ-----TCSCHAKWSGEDCSKEVCSL---ECGPHGRC----VGESCSCAAG 1064
            G  T  V+T       C C   +SG  C   + S     C   G C    +   C C AG
Sbjct: 81   GSATC-VNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAG 139

Query: 1065 WSGEFCSV---RLCDARCAEHGQCKNG----TCLCVSGWNGRHCTLE--GCPRS-CAGHG 1114
            ++G FC +       + C     C++G    +C CV G+ GRHC LE   C    C    
Sbjct: 140  YAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEA 199

Query: 1115 QCRVDNDGRWECKC---FDGWDGPDC 1137
             C ++  GR+ C C   + G+ G  C
Sbjct: 200  TC-LNEIGRYTCICPHNYSGYTGAQC 224



 Score = 54.4 bits (125), Expect = 6e-06
 Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 1059 CSCAAGWSGEFCSVRL--CDARCAEHGQCKNGT----CLCVSGWNGRHCT--LEGCPRSC 1110
            CSC  GWSG+ C + +  C +    HG C +      C C  G+ G +C   ++ C    
Sbjct: 1051 CSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ 1110

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC--TTLKEQICDDSRDN 1151
              +G   + +   + C CF  + G  C  + L   +C + + N
Sbjct: 1111 CANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTN 1153



 Score = 42.3 bits (95), Expect = 0.026
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 8/73 (10%)

Query: 1072 VRLCDAR-CAEHGQCKN----GTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDGRW 1124
            + +C++  C   G C++      C C  GW+G+HC L  + C  +   HG C  D    +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS-DRVAAY 1086

Query: 1125 ECKCFDGWDGPDC 1137
             C C  G+ G +C
Sbjct: 1087 HCTCEPGYTGVNC 1099



 Score = 40.3 bits (90), Expect = 0.10
 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 24/134 (17%)

Query: 892  HCQCQPGFGGDDCSKSV--CPVLCSQRG----EYING-ECQCNPGWKGKEC-------SL 937
            HC C+PG+ G +C   +  C       G     + NG  C C   + GK C       ++
Sbjct: 1087 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1146

Query: 938  RHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFC-GEID-CPHPTCSGHGFCIE---- 987
              +E     C   G+C       KC C  G+ G++C  +ID C    C   G C +    
Sbjct: 1147 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1206

Query: 988  GTCVCKKGWKGADC 1001
              C+C   + G  C
Sbjct: 1207 FQCLCDVAFAGERC 1220


>AK074121-1|BAB84947.1|  491|Homo sapiens FLJ00193 protein protein.
          Length = 491

 Score = 72.9 bits (171), Expect = 2e-11
 Identities = 56/185 (30%), Positives = 77/185 (41%), Gaps = 36/185 (19%)

Query: 951  GHCVNGKC--SCVRGYKGKFCGEIDCPHPTCSGHGFCI--EGTCVCKKGWKGADCGTM-- 1004
            G  +  +C  SC  G  G  C    C   TC   G C+   G CVC  G++G  C     
Sbjct: 10   GFWMGARCHLSCPEGLWGVNCSNT-C---TCKNGGTCLPENGNCVCAPGFRGPSCQRSCQ 65

Query: 1005 -DKDALQCLP-DCSGHGTFDVDTQTCSCHAKWSGEDCSK--------EVCSLECGPH--G 1052
              +   +C+P  C+ H        TC C A W+G DCS+        E C+  C  H  G
Sbjct: 66   PGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGG 125

Query: 1053 RCVGE--SCSCAAGWSG----EFCSVRLCDARCAEHGQC--------KNGTCLCVSGWNG 1098
             C  +  SC C  GW+G    E C +    A C++  QC        + G C+C  G +G
Sbjct: 126  TCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSG 185

Query: 1099 RHCTL 1103
              C +
Sbjct: 186  APCRI 190



 Score = 64.1 bits (149), Expect = 7e-09
 Identities = 64/205 (31%), Positives = 79/205 (38%), Gaps = 52/205 (25%)

Query: 877  NCPNGCSGK--GECLM--GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKG 932
            NC N C+ K  G CL   G+C C PGF G  C +S                  C PG  G
Sbjct: 29   NCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRS------------------CQPGRYG 70

Query: 933  KECSLRHDECEVPDCNGHGHC--VNGKCSCVRGYKGKFCGEIDCPHPTCSGH-GFCIEGT 989
            K C      C+   C  H  C   NG C C+ G+ G      DC  P   GH G     T
Sbjct: 71   KRCV----PCK---CANHSFCHPSNGTCYCLAGWTGP-----DCSQPCPPGHWGENCAQT 118

Query: 990  CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECG 1049
            C C     G  C   D   + C    +GH   +       C     G +CS + C  +CG
Sbjct: 119  CQCH---HGGTCHPQDGSCI-CPLGWTGHHCLE------GCPLGTFGANCS-QPC--QCG 165

Query: 1050 PHGRCVGE--SCSCAAGWSGEFCSV 1072
            P  +C  E  +C C  G SG  C +
Sbjct: 166  PGEKCHPETGACVCPPGHSGAPCRI 190



 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 37/108 (34%), Positives = 43/108 (39%), Gaps = 19/108 (17%)

Query: 1044 CSLECGPHGRCVGESC--SCAAGWSGEFCSVRLCDARCAEHGQC--KNGTCLCVSGWNGR 1099
            CS      G  +G  C  SC  G  G  CS   C   C   G C  +NG C+C  G+ G 
Sbjct: 2    CSWTLSVPGFWMGARCHLSCPEGLWGVNCS-NTCT--CKNGGTCLPENGNCVCAPGFRGP 58

Query: 1100 HCTL--------EGC-PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCT 1138
             C          + C P  CA H  C   N     C C  GW GPDC+
Sbjct: 59   SCQRSCQPGRYGKRCVPCKCANHSFCHPSNG---TCYCLAGWTGPDCS 103


>AF009227-1|AAC51756.1|  768|Homo sapiens gamma-heregulin protein.
          Length = 768

 Score = 72.5 bits (170), Expect = 2e-11
 Identities = 38/136 (27%), Positives = 70/136 (51%), Gaps = 15/136 (11%)

Query: 747 PAQSFPPDGTTFK-QITLGEKLSKEIPPYSYWNMQFYQSQSSYVNFDYLIPRGASIGVYA 805
           P+  FP D      +I +G + S++IPP ++W  Q +     ++ F+  + + A +G+Y 
Sbjct: 421 PSSFFPEDSFIDSGEIDVGRRASQKIPPGTFWRSQVFIDHPVHLKFNVSLGKAALVGIYG 480

Query: 806 RRNALPTHTQYNFLEVLTGFK------------ARTTRASYPSVKKEV--THYMEQGPWF 851
           R+   P+HTQ++F+E+L G +             R +R + P    E     Y++ G W 
Sbjct: 481 RKGLPPSHTQFDFVELLDGRRLLTQEARSLEGTPRQSRGTVPPSSHETGFIQYLDSGIWH 540

Query: 852 LSLYNDDGDPQEISFV 867
           L+ YND  + + +SF+
Sbjct: 541 LAFYNDGKESEVVSFL 556


>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
          Length = 1523

 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 69/250 (27%), Positives = 100/250 (40%), Gaps = 43/250 (17%)

Query: 861  PQEISFVALVAEEMTHNCPN-GCSGKGECLMGHCQCQPGFGGDDCSKSVCPVL------- 912
            P +I+ VA     ++  C N G   +    +  C C   + G DC+  +   +       
Sbjct: 908  PVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHG 967

Query: 913  --CSQRGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYK 965
              C     + +G  C C  G++G+ C +  D+CE  DC  +  CV+G     C C   Y 
Sbjct: 968  GTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYT 1027

Query: 966  GKFCGE-IDCPHP---TCSGHGFCI---EG-TCVCKKGWKGADCGTMDKDALQCLPDCSG 1017
            G+ C E ID   P    C     CI   +G +C C  G+ G  C T D D   C+     
Sbjct: 1028 GELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCET-DND--DCVAHKCR 1084

Query: 1018 HGTFDVDT---QTCSCHAKWSGEDC---------SKEVC-SLECGPHGRCV----GESCS 1060
            HG   VDT    TC+C   +SG  C             C   EC    +C+      +C 
Sbjct: 1085 HGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCR 1144

Query: 1061 CAAGWSGEFC 1070
            C  G++G  C
Sbjct: 1145 CPPGFAGPRC 1154



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 70/241 (29%), Positives = 94/241 (39%), Gaps = 45/241 (18%)

Query: 942  CEVPDCNGHGHCVNG-----KCSCVRGYKGKFCG-EID-CPHPTCSGHGFCI------EG 988
            C    C  +G C        +C+C   YKGK C   I+ C    C   G C       +G
Sbjct: 920  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979

Query: 989  -TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV-- 1043
             +C C  G++G  C     D      DC  + T    ++   C C   ++GE C + +  
Sbjct: 980  FSCSCPLGFEGQRCEINPDDCED--NDCENNATCVDGINNYVCICPPNYTGELCDEVIDH 1037

Query: 1044 CSLE---CGPHGRCV----GESCSCAAGWSGEFCSVRL--CDARCAEHG-QCK---NG-T 1089
            C  E   C    +C+    G SC C  G+SG+ C      C A    HG QC    NG T
Sbjct: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097

Query: 1090 CLCVSGWNGRHCT-------LEGCP---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            C C  G++G  C        L+  P     C    QC V       C+C  G+ GP C  
Sbjct: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEP-TCRCPPGFAGPRCEK 1156

Query: 1140 L 1140
            L
Sbjct: 1157 L 1157



 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 57/226 (25%), Positives = 84/226 (37%), Gaps = 37/226 (16%)

Query: 974  CPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDV----- 1023
            C    C  +G C +       C C   +KG DC       +Q    C   GT  +     
Sbjct: 920  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQ--NPCQHGGTCHLSDSHK 977

Query: 1024 DTQTCSCHAKWSGEDC--SKEVCS-LECGPHGRCV----GESCSCAAGWSGEFCS--VRL 1074
            D  +CSC   + G+ C  + + C   +C  +  CV       C C   ++GE C   +  
Sbjct: 978  DGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDH 1037

Query: 1075 CDAR---CAEHGQC----KNGTCLCVSGWNGRHCTLEG--CPRSCAGHGQCRVDNDGRWE 1125
            C      C    +C    K  +C CV G++G+ C  +   C      HG   VD    + 
Sbjct: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097

Query: 1126 CKCFDGWDGPDC------TTLKEQICDDSR-DNDKDGLVDCEDPEC 1164
            C C  G+ GP C        L+   CD     N    +V  ++P C
Sbjct: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTC 1143



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 17/98 (17%)

Query: 1024 DTQTCSCHAKWSGEDCSKEV---CSLECGPHGRCV--GES--CSCAAGWSGEFC-----S 1071
            D+  C C   W+G  C +E    C      HG+CV  G S  C CA G+ G+ C     S
Sbjct: 1349 DSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDS 1408

Query: 1072 VRLCDARCAEHGQCKNGT-----CLCVSGWNGRHCTLE 1104
               C A    HGQC         CLC  G++G HC  E
Sbjct: 1409 ANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE 1446



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 14/92 (15%)

Query: 1059 CSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNGT---CLCVSGWNGRHC-----TLEG 1105
            C C  GW+G  C     D     RC  HG+C   GT   C C  G+ G  C     +   
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRC-HHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANA 1411

Query: 1106 CPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C      HGQC + + G   C C  G+ G  C
Sbjct: 1412 CSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1443



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 31/92 (33%), Positives = 38/92 (41%), Gaps = 15/92 (16%)

Query: 924  CQCNPGWKGKECSLR-HDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEIDCPHPT 978
            C+C PGW G  C     D C    C+ HG CV    +  C C  GY G  C   +     
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRCH-HGKCVATGTSYMCKCAEGYGGDLCDNKNDSANA 1411

Query: 979  CSG----HGFCI-----EGTCVCKKGWKGADC 1001
            CS     HG C      E  C+C+ G+ G  C
Sbjct: 1412 CSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1443



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 39/115 (33%), Positives = 46/115 (40%), Gaps = 21/115 (18%)

Query: 974  CPHPTCSGHGFC--IEG---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT- 1027
            C   T   HG C  +E     C C+ GW G  C    +D   CL     HG   V T T 
Sbjct: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARD--PCLGHRCHHGKC-VATGTS 1388

Query: 1028 --CSCHAKWSGEDC-----SKEVCSLECGPHGRC----VGES-CSCAAGWSGEFC 1070
              C C   + G+ C     S   CS     HG+C     GE  C C  G+SGE C
Sbjct: 1389 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1443



 Score = 38.3 bits (85), Expect = 0.42
 Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 13/71 (18%)

Query: 876  HNCPNG-CSGKGECLMGHCQCQPGFGGDDC-----SKSVCPVLCSQRGE-YIN--GE--C 924
            H C +G C   G   M  C+C  G+GGD C     S + C       G+ +I+  GE  C
Sbjct: 1375 HRCHHGKCVATGTSYM--CKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYC 1432

Query: 925  QCNPGWKGKEC 935
             C PG+ G+ C
Sbjct: 1433 LCQPGFSGEHC 1443



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 25/139 (17%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQR---GEYI----NGECQCNPGWKGKECSLRHDE---C 942
            C+C+PG+ G  C +         R   G+ +    +  C+C  G+ G  C  ++D    C
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 1412

Query: 943  EVPDCNGHGHC-VNGK----CSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C+ HG C ++ +    C C  G+ G+ C +    +P C G    +      +KG+ 
Sbjct: 1413 SAFKCH-HGQCHISDQGEPYCLCQPGFSGEHCQQ---ENP-CLGQ--VVREVIRRQKGY- 1464

Query: 998  GADCGTMDK-DALQCLPDC 1015
             A C T  K   ++C   C
Sbjct: 1465 -ASCATASKVPIMECRGGC 1482


>AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein.
          Length = 1055

 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 68/228 (29%), Positives = 102/228 (44%), Gaps = 54/228 (23%)

Query: 960  CVRGYKGKFCGEIDCP---HPTCSGHGFCIE-----GTCVCKKGWKGAD---CGTMDKDA 1008
            C +G+ G  C +  CP      CSG+G C +     GTC+C++G++G+    C   +K  
Sbjct: 161  CCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 218

Query: 1009 LQCLPDC-SGHGTFD--VDTQ----TCSCHAKWSGEDCSKEVCSLECGP-------HGRC 1054
             +C   C   HGT +  +D+     T +C    +G  C K+  +  CGP       H  C
Sbjct: 219  PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA--CGPYVQFCHIHATC 276

Query: 1055 V----GESCSCAAGWSGE--FCS-----VRLCDARCAEHGQCKN-----GTCLCVSGW-- 1096
                   SC C AG+ G+   CS       L    C+ + +C N      TC+C  GW  
Sbjct: 277  EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECINTGTGTHTCVCQQGWTG 336

Query: 1097 NGRHCT-LEGC--PRS--CAGHGQCRVDNDGRWECKCFDGW--DGPDC 1137
            NGR C+ +  C  P +  C  +  C     G+ EC+C  G+  +G DC
Sbjct: 337  NGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDC 384



 Score = 67.7 bits (158), Expect = 6e-10
 Identities = 82/299 (27%), Positives = 116/299 (38%), Gaps = 67/299 (22%)

Query: 880  NGCSGKGECLMGHCQCQPGFGGDDCSKSVCPV----LCSQRGEYI-----NGECQCNPGW 930
            +GC+      +   +C  GF G DC++  CP      CS  G+       NG C C  G+
Sbjct: 146  SGCARYCNATVKIPKCCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGF 203

Query: 931  KGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTC 990
            +G +C      C  P  N +G   N KC CV G        ID         G C+ GTC
Sbjct: 204  QGSQCQF----CSDP--NKYGPRCNKKCLCVHGTCNN---RID-------SDGACLTGTC 247

Query: 991  VCKKGWKGADCGTMDKDALQCLPD---CSGHGTFDVD--TQTCSCHAKWSGED--CSK-E 1042
              + G  G  C   DK    C P    C  H T +    T +C C A + G+   CS+ +
Sbjct: 248  --RDGSAGRLC---DKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMD 302

Query: 1043 VCSL----ECGPHGRCVG-----ESCSCAAGWSGEF--CS-VRLC----DARCAEHGQCK 1086
             C+      C  +  C+       +C C  GW+G    CS +  C       C ++  C 
Sbjct: 303  PCTGLTPGGCSRNAECINTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCL 362

Query: 1087 -----NGTCLCVSGW--NGRHCT-LEGCPRS---CAGHGQCRVDNDGRWECKCFDGWDG 1134
                    C C  G+  NG  C  +  C      C     C+  + G W C C +G++G
Sbjct: 363  YVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 421



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 63/256 (24%), Positives = 90/256 (35%), Gaps = 47/256 (18%)

Query: 877  NCPNGCSGKGECL-----MGHCQCQPGFGGDDCSKSV-------CPVLCS------QRGE 918
            N  N C G G CL      G C+C  GF G  C           C   CS       +G 
Sbjct: 784  NAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGP 843

Query: 919  YINGECQCNPGWKGKEC--SLRHDECEVPDCNGHGHCVNGK-----CSCVRGYKGKFCGE 971
              +G C C+ GW+G  C  +   D C    C+   +C+        C C  G++G   G 
Sbjct: 844  LGDGSCDCDVGWRGVHCDNATTEDNCN-GTCHTSANCLTNSDGTASCKCAAGFQGN--GT 900

Query: 972  IDCPHPTCSGHGFCIEGTCVCKKGWKGADCG--TMDKDALQCLPDCSGHGTFDVDTQTCS 1029
            I      C        G C  K     ADC   T  +    C    +G G   ++   C 
Sbjct: 901  ICTAINACE----ISNGGCSAK-----ADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCL 951

Query: 1030 CHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDARCAEHGQCKNGT 1089
                  G  C K     + GP+      +C+C   ++G+     L +    ++G C    
Sbjct: 952  --ENHCG--CDKNAECTQTGPNQA----ACNCLPAYTGDGKVCTLINVCLTKNGGCSEFA 1003

Query: 1090 CLCVSGWNGRHCTLEG 1105
                +G   R CT +G
Sbjct: 1004 ICNHTGQVERTCTCKG 1019



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 17/93 (18%)

Query: 1059 CSCAAGWSGEFCSVRL-------CDARCA-EHGQCK-----NGTCLCVSGWNGRHC---- 1101
            C C  G+SG  C           CD  C+  HG+C      +G+C C  GW G HC    
Sbjct: 805  CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 864

Query: 1102 TLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDG 1134
            T + C  +C     C  ++DG   CKC  G+ G
Sbjct: 865  TEDNCNGTCHTSANCLTNSDGTASCKCAAGFQG 897



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 59/211 (27%), Positives = 80/211 (37%), Gaps = 54/211 (25%)

Query: 960  CVRGYKGKFCGEIDCP---HPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQC 1011
            C  G+ G  C    CP      C G+G C++G      C C +G+ G  C T        
Sbjct: 769  CCAGFFGPQCQP--CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET-------- 818

Query: 1012 LPDCSGHGTFDVDT-QTCSC-HAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEF 1069
               C+  G + +   Q CSC H +     C++       GP G     SC C  GW G  
Sbjct: 819  ---CT-EGKYGIHCDQACSCVHGR-----CNQ-------GPLG---DGSCDCDVGWRGVH 859

Query: 1070 CSVRL----CDARCAEHGQC---KNGT--CLCVSGW--NGRHCT-LEGCPRS---CAGHG 1114
            C        C+  C     C    +GT  C C +G+  NG  CT +  C  S   C+   
Sbjct: 860  CDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKA 919

Query: 1115 QCRVDNDGRWECKCFDGWDGPDCTTLKEQIC 1145
             C+    GR  C C  G+ G     L+   C
Sbjct: 920  DCKRTTPGRRVCTCKAGYTGDGIVCLEINPC 950



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 16/125 (12%)

Query: 1061 CAAGWSGEFCSVRLCDAR--CAEHGQCK---NGT--CLCVSGWNGRHCTL--EG-----C 1106
            C AG+ G  C     +A+  C  +G C    NGT  C C  G++G  C    EG     C
Sbjct: 769  CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 828

Query: 1107 PRSCAG-HGQCRVDNDGRWECKCFDGWDGPDC-TTLKEQICDDSRDNDKDGLVDCEDPEC 1164
             ++C+  HG+C     G   C C  GW G  C     E  C+ +     + L + +    
Sbjct: 829  DQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTAS 888

Query: 1165 CQSPA 1169
            C+  A
Sbjct: 889  CKCAA 893



 Score = 37.9 bits (84), Expect = 0.55
 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 10/85 (11%)

Query: 1065 WSGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTL--EGCPRSCAGHGQCRVDNDG 1122
            +SG F S++   + CA +         C  G+ G  C     G    C+G+GQC     G
Sbjct: 137  YSGRFGSLK---SGCARYCNATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGG 193

Query: 1123 RWECKCFDGWDGPDCTTLKEQICDD 1147
               C C +G+ G  C     Q C D
Sbjct: 194  NGTCICEEGFQGSQC-----QFCSD 213


>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
          Length = 1523

 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 69/250 (27%), Positives = 100/250 (40%), Gaps = 43/250 (17%)

Query: 861  PQEISFVALVAEEMTHNCPN-GCSGKGECLMGHCQCQPGFGGDDCSKSVCPVL------- 912
            P +I+ VA     ++  C N G   +    +  C C   + G DC+  +   +       
Sbjct: 908  PVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHG 967

Query: 913  --CSQRGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYK 965
              C     + +G  C C  G++G+ C +  D+CE  DC  +  CV+G     C C   Y 
Sbjct: 968  GTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYT 1027

Query: 966  GKFCGE-IDCPHP---TCSGHGFCI---EG-TCVCKKGWKGADCGTMDKDALQCLPDCSG 1017
            G+ C E ID   P    C     CI   +G +C C  G+ G  C T D D   C+     
Sbjct: 1028 GELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCET-DND--DCVAHKCR 1084

Query: 1018 HGTFDVDT---QTCSCHAKWSGEDC---------SKEVC-SLECGPHGRCV----GESCS 1060
            HG   VDT    TC+C   +SG  C             C   EC    +C+      +C 
Sbjct: 1085 HGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCR 1144

Query: 1061 CAAGWSGEFC 1070
            C  G++G  C
Sbjct: 1145 CPPGFAGPRC 1154



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 70/241 (29%), Positives = 94/241 (39%), Gaps = 45/241 (18%)

Query: 942  CEVPDCNGHGHCVNG-----KCSCVRGYKGKFCG-EID-CPHPTCSGHGFCI------EG 988
            C    C  +G C        +C+C   YKGK C   I+ C    C   G C       +G
Sbjct: 920  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979

Query: 989  -TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV-- 1043
             +C C  G++G  C     D      DC  + T    ++   C C   ++GE C + +  
Sbjct: 980  FSCSCPLGFEGQRCEINPDDCED--NDCENNATCVDGINNYVCICPPNYTGELCDEVIDH 1037

Query: 1044 CSLE---CGPHGRCV----GESCSCAAGWSGEFCSVRL--CDARCAEHG-QCK---NG-T 1089
            C  E   C    +C+    G SC C  G+SG+ C      C A    HG QC    NG T
Sbjct: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097

Query: 1090 CLCVSGWNGRHCT-------LEGCP---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            C C  G++G  C        L+  P     C    QC V       C+C  G+ GP C  
Sbjct: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEP-TCRCPPGFAGPRCEK 1156

Query: 1140 L 1140
            L
Sbjct: 1157 L 1157



 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 57/226 (25%), Positives = 84/226 (37%), Gaps = 37/226 (16%)

Query: 974  CPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDV----- 1023
            C    C  +G C +       C C   +KG DC       +Q    C   GT  +     
Sbjct: 920  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQ--NPCQHGGTCHLSDSHK 977

Query: 1024 DTQTCSCHAKWSGEDC--SKEVCS-LECGPHGRCV----GESCSCAAGWSGEFCS--VRL 1074
            D  +CSC   + G+ C  + + C   +C  +  CV       C C   ++GE C   +  
Sbjct: 978  DGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDH 1037

Query: 1075 CDAR---CAEHGQC----KNGTCLCVSGWNGRHCTLEG--CPRSCAGHGQCRVDNDGRWE 1125
            C      C    +C    K  +C CV G++G+ C  +   C      HG   VD    + 
Sbjct: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097

Query: 1126 CKCFDGWDGPDC------TTLKEQICDDSR-DNDKDGLVDCEDPEC 1164
            C C  G+ GP C        L+   CD     N    +V  ++P C
Sbjct: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTC 1143



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 17/98 (17%)

Query: 1024 DTQTCSCHAKWSGEDCSKEV---CSLECGPHGRCV--GES--CSCAAGWSGEFC-----S 1071
            D+  C C   W+G  C +E    C      HG+CV  G S  C CA G+ G+ C     S
Sbjct: 1349 DSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDS 1408

Query: 1072 VRLCDARCAEHGQCKNGT-----CLCVSGWNGRHCTLE 1104
               C A    HGQC         CLC  G++G HC  E
Sbjct: 1409 ANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE 1446



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 14/92 (15%)

Query: 1059 CSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNGT---CLCVSGWNGRHC-----TLEG 1105
            C C  GW+G  C     D     RC  HG+C   GT   C C  G+ G  C     +   
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRC-HHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANA 1411

Query: 1106 CPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C      HGQC + + G   C C  G+ G  C
Sbjct: 1412 CSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1443



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 31/92 (33%), Positives = 38/92 (41%), Gaps = 15/92 (16%)

Query: 924  CQCNPGWKGKECSLR-HDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEIDCPHPT 978
            C+C PGW G  C     D C    C+ HG CV    +  C C  GY G  C   +     
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRCH-HGKCVATGTSYMCKCAEGYGGDLCDNKNDSANA 1411

Query: 979  CSG----HGFCI-----EGTCVCKKGWKGADC 1001
            CS     HG C      E  C+C+ G+ G  C
Sbjct: 1412 CSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1443



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 39/115 (33%), Positives = 46/115 (40%), Gaps = 21/115 (18%)

Query: 974  CPHPTCSGHGFC--IEG---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT- 1027
            C   T   HG C  +E     C C+ GW G  C    +D   CL     HG   V T T 
Sbjct: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARD--PCLGHRCHHGKC-VATGTS 1388

Query: 1028 --CSCHAKWSGEDC-----SKEVCSLECGPHGRC----VGES-CSCAAGWSGEFC 1070
              C C   + G+ C     S   CS     HG+C     GE  C C  G+SGE C
Sbjct: 1389 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1443



 Score = 38.3 bits (85), Expect = 0.42
 Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 13/71 (18%)

Query: 876  HNCPNG-CSGKGECLMGHCQCQPGFGGDDC-----SKSVCPVLCSQRGE-YIN--GE--C 924
            H C +G C   G   M  C+C  G+GGD C     S + C       G+ +I+  GE  C
Sbjct: 1375 HRCHHGKCVATGTSYM--CKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYC 1432

Query: 925  QCNPGWKGKEC 935
             C PG+ G+ C
Sbjct: 1433 LCQPGFSGEHC 1443



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 25/139 (17%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQR---GEYI----NGECQCNPGWKGKECSLRHDE---C 942
            C+C+PG+ G  C +         R   G+ +    +  C+C  G+ G  C  ++D    C
Sbjct: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 1412

Query: 943  EVPDCNGHGHC-VNGK----CSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C+ HG C ++ +    C C  G+ G+ C +    +P C G    +      +KG+ 
Sbjct: 1413 SAFKCH-HGQCHISDQGEPYCLCQPGFSGEHCQQ---ENP-CLGQ--VVREVIRRQKGY- 1464

Query: 998  GADCGTMDK-DALQCLPDC 1015
             A C T  K   ++C   C
Sbjct: 1465 -ASCATASKVPIMECRGGC 1482


>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
          Length = 1559

 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 69/250 (27%), Positives = 100/250 (40%), Gaps = 43/250 (17%)

Query: 861  PQEISFVALVAEEMTHNCPN-GCSGKGECLMGHCQCQPGFGGDDCSKSVCPVL------- 912
            P +I+ VA     ++  C N G   +    +  C C   + G DC+  +   +       
Sbjct: 944  PVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHG 1003

Query: 913  --CSQRGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYK 965
              C     + +G  C C  G++G+ C +  D+CE  DC  +  CV+G     C C   Y 
Sbjct: 1004 GTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYT 1063

Query: 966  GKFCGE-IDCPHP---TCSGHGFCI---EG-TCVCKKGWKGADCGTMDKDALQCLPDCSG 1017
            G+ C E ID   P    C     CI   +G +C C  G+ G  C T D D   C+     
Sbjct: 1064 GELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCET-DND--DCVAHKCR 1120

Query: 1018 HGTFDVDT---QTCSCHAKWSGEDC---------SKEVC-SLECGPHGRCV----GESCS 1060
            HG   VDT    TC+C   +SG  C             C   EC    +C+      +C 
Sbjct: 1121 HGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCR 1180

Query: 1061 CAAGWSGEFC 1070
            C  G++G  C
Sbjct: 1181 CPPGFAGPRC 1190



 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 70/241 (29%), Positives = 94/241 (39%), Gaps = 45/241 (18%)

Query: 942  CEVPDCNGHGHCVNG-----KCSCVRGYKGKFCG-EID-CPHPTCSGHGFCI------EG 988
            C    C  +G C        +C+C   YKGK C   I+ C    C   G C       +G
Sbjct: 956  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 1015

Query: 989  -TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKWSGEDCSKEV-- 1043
             +C C  G++G  C     D      DC  + T    ++   C C   ++GE C + +  
Sbjct: 1016 FSCSCPLGFEGQRCEINPDDCED--NDCENNATCVDGINNYVCICPPNYTGELCDEVIDH 1073

Query: 1044 CSLE---CGPHGRCV----GESCSCAAGWSGEFCSVRL--CDARCAEHG-QCK---NG-T 1089
            C  E   C    +C+    G SC C  G+SG+ C      C A    HG QC    NG T
Sbjct: 1074 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1133

Query: 1090 CLCVSGWNGRHCT-------LEGCP---RSCAGHGQCRVDNDGRWECKCFDGWDGPDCTT 1139
            C C  G++G  C        L+  P     C    QC V       C+C  G+ GP C  
Sbjct: 1134 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEP-TCRCPPGFAGPRCEK 1192

Query: 1140 L 1140
            L
Sbjct: 1193 L 1193



 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 57/226 (25%), Positives = 84/226 (37%), Gaps = 37/226 (16%)

Query: 974  CPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDV----- 1023
            C    C  +G C +       C C   +KG DC       +Q    C   GT  +     
Sbjct: 956  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQ--NPCQHGGTCHLSDSHK 1013

Query: 1024 DTQTCSCHAKWSGEDC--SKEVCS-LECGPHGRCV----GESCSCAAGWSGEFCS--VRL 1074
            D  +CSC   + G+ C  + + C   +C  +  CV       C C   ++GE C   +  
Sbjct: 1014 DGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDH 1073

Query: 1075 CDAR---CAEHGQC----KNGTCLCVSGWNGRHCTLEG--CPRSCAGHGQCRVDNDGRWE 1125
            C      C    +C    K  +C CV G++G+ C  +   C      HG   VD    + 
Sbjct: 1074 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1133

Query: 1126 CKCFDGWDGPDC------TTLKEQICDDSR-DNDKDGLVDCEDPEC 1164
            C C  G+ GP C        L+   CD     N    +V  ++P C
Sbjct: 1134 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTC 1179



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 17/98 (17%)

Query: 1024 DTQTCSCHAKWSGEDCSKEV---CSLECGPHGRCV--GES--CSCAAGWSGEFC-----S 1071
            D+  C C   W+G  C +E    C      HG+CV  G S  C CA G+ G+ C     S
Sbjct: 1385 DSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDS 1444

Query: 1072 VRLCDARCAEHGQCKNGT-----CLCVSGWNGRHCTLE 1104
               C A    HGQC         CLC  G++G HC  E
Sbjct: 1445 ANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE 1482



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 14/92 (15%)

Query: 1059 CSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNGT---CLCVSGWNGRHC-----TLEG 1105
            C C  GW+G  C     D     RC  HG+C   GT   C C  G+ G  C     +   
Sbjct: 1389 CECRPGWTGPLCDQEARDPCLGHRC-HHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANA 1447

Query: 1106 CPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C      HGQC + + G   C C  G+ G  C
Sbjct: 1448 CSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1479



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 31/92 (33%), Positives = 38/92 (41%), Gaps = 15/92 (16%)

Query: 924  CQCNPGWKGKECSLR-HDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEIDCPHPT 978
            C+C PGW G  C     D C    C+ HG CV    +  C C  GY G  C   +     
Sbjct: 1389 CECRPGWTGPLCDQEARDPCLGHRCH-HGKCVATGTSYMCKCAEGYGGDLCDNKNDSANA 1447

Query: 979  CSG----HGFCI-----EGTCVCKKGWKGADC 1001
            CS     HG C      E  C+C+ G+ G  C
Sbjct: 1448 CSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1479



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 39/115 (33%), Positives = 46/115 (40%), Gaps = 21/115 (18%)

Query: 974  CPHPTCSGHGFC--IEG---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT- 1027
            C   T   HG C  +E     C C+ GW G  C    +D   CL     HG   V T T 
Sbjct: 1368 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARD--PCLGHRCHHGKC-VATGTS 1424

Query: 1028 --CSCHAKWSGEDC-----SKEVCSLECGPHGRC----VGES-CSCAAGWSGEFC 1070
              C C   + G+ C     S   CS     HG+C     GE  C C  G+SGE C
Sbjct: 1425 YMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1479



 Score = 38.3 bits (85), Expect = 0.42
 Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 13/71 (18%)

Query: 876  HNCPNG-CSGKGECLMGHCQCQPGFGGDDC-----SKSVCPVLCSQRGE-YIN--GE--C 924
            H C +G C   G   M  C+C  G+GGD C     S + C       G+ +I+  GE  C
Sbjct: 1411 HRCHHGKCVATGTSYM--CKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYC 1468

Query: 925  QCNPGWKGKEC 935
             C PG+ G+ C
Sbjct: 1469 LCQPGFSGEHC 1479



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 25/139 (17%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQR---GEYI----NGECQCNPGWKGKECSLRHDE---C 942
            C+C+PG+ G  C +         R   G+ +    +  C+C  G+ G  C  ++D    C
Sbjct: 1389 CECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 1448

Query: 943  EVPDCNGHGHC-VNGK----CSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C+ HG C ++ +    C C  G+ G+ C +    +P C G    +      +KG+ 
Sbjct: 1449 SAFKCH-HGQCHISDQGEPYCLCQPGFSGEHCQQ---ENP-CLGQ--VVREVIRRQKGY- 1500

Query: 998  GADCGTMDK-DALQCLPDC 1015
             A C T  K   ++C   C
Sbjct: 1501 -ASCATASKVPIMECRGGC 1518


>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
          Length = 3002

 Score = 70.9 bits (166), Expect = 6e-11
 Identities = 93/338 (27%), Positives = 139/338 (41%), Gaps = 69/338 (20%)

Query: 887  ECLMGHCQCQPGFGG----DDCSKS--VCPV--LCSQRGEYINGECQCNPGWKGKECSL- 937
            EC  GH Q  P        ++C  S  +CP     +  G+Y   +C CNPG+      L 
Sbjct: 1270 ECPPGH-QLSPNISACIDINECELSAHLCPNGRCVNLIGKY---QCACNPGYHSTPDRLF 1325

Query: 938  --RHDECEVPDCNGHGHCVNGK----CSCVRGYK----GKFCGEID-CP-HPTCSGHGFC 985
                DEC + +      C N +    CSC  G+      + C +ID C  +P     G C
Sbjct: 1326 CVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC 1385

Query: 986  I----EGTCVCKKGWKGADCGTMDKDALQC--LPDCSGHGTFDVDTQT--CSCHAKWSGE 1037
                 E  C+C  G+  ++      D  +C   P+    GT +    +  C C   +SG+
Sbjct: 1386 TNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGK 1445

Query: 1038 D----CSK----EVCSLECGPHGRCVGES----CSCAAGWSGEFCSVRLCDA------RC 1079
                 C+     E+ +  CG H  C   +    CSC+ GW G+       D        C
Sbjct: 1446 KGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMC 1505

Query: 1080 AEHGQCKN--GT--CLCVSGW--NGRHCT-LEGCPR--SCAGHGQCRVDNDGRWECKCFD 1130
            ++H  CKN  G+  CLC  G+  +G  CT L+ C    +  G+GQC ++  G + C+C  
Sbjct: 1506 SQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQC-LNAPGGYRCECDM 1564

Query: 1131 GW----DGPDCTTLKE----QICDDSRDNDKDGLVDCE 1160
            G+    DG  C  + E     IC     ++  GL  CE
Sbjct: 1565 GFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCE 1602



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 35/106 (33%), Positives = 46/106 (43%), Gaps = 9/106 (8%)

Query: 1036 GEDCSKEVCSLECGPHGRCVGES-CSCAAGWSGEFC---SVRLCDARCAEHGQCKNGTCL 1091
            G  C   +C   CG  G C   + C+C +G     C   S++ C+ RC   G C +  CL
Sbjct: 208  GNQCIVPICRHSCGD-GFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCL 266

Query: 1092 CVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C  G+ G HC    C   C   G+C   N     C C  G+ GP C
Sbjct: 267  CQKGYIGTHCGQPVCESGCLNGGRCVAPN----RCACTYGFTGPQC 308



 Score = 64.5 bits (150), Expect = 6e-09
 Identities = 65/240 (27%), Positives = 83/240 (34%), Gaps = 39/240 (16%)

Query: 895  CQPGF----GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH-DECEVPDCNG 949
            C PG+    GG+ C   +C   C          C C  G     C  R    C +   NG
Sbjct: 198  CCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNG 257

Query: 950  HGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDA 1008
             G C +  C C +GY G  CG+  C    C   G C+    C C  G+ G  C   D   
Sbjct: 258  -GSCSDDHCLCQKGYIGTHCGQPVC-ESGCLNGGRCVAPNRCACTYGFTGPQC-ERDYRT 314

Query: 1009 LQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE 1068
              C    S             C  + SG  C+K +C   C   GR  G  C        E
Sbjct: 315  GPCFTVISNQ----------MCQGQLSGIVCTKTLC---CATVGRAWGHPC--------E 353

Query: 1069 FCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKC 1128
             C  +    R       + G C  V       C  +  P  C G G C ++  G +ECKC
Sbjct: 354  MCPAQPHPCRRGFIPNIRTGACQDVD-----EC--QAIPGLCQG-GNC-INTVGSFECKC 404



 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 68/254 (26%), Positives = 106/254 (41%), Gaps = 50/254 (19%)

Query: 940  DECEV-PDCNGHGHCVNG----KCSCVRGYKGKFCGEI----DCPH-PTCSGHGFCIEGT 989
            DEC+  P C  +  C+N     +C C  GY+    G+     +C   P    HG CI+  
Sbjct: 1941 DECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTV 2000

Query: 990  ----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKW---SGEDC- 1039
                C+C  G+K  D  TM  D  +C  D  G+GT    + +  C C+  +      DC 
Sbjct: 2001 GSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCI 2060

Query: 1040 SKEVCSLECG---PHGRCVGE----SCSCAAGW----SGEFC-SVRLC--DARCAEHGQC 1085
              + C+   G    +G+C+       C C  G+     G  C  +  C  + R    G C
Sbjct: 2061 DVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTC 2120

Query: 1086 KN--GT--CLCVSGWN--GRHC-TLEGC---PRSCAGHGQCRVDNDGRWECKCFDGW--- 1132
            +N  G+  C+C  G++     C  ++ C   P  CA  G C  + +G ++C C +G+   
Sbjct: 2121 QNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICA-LGTCS-NTEGSFKCLCPEGFSLS 2178

Query: 1133 -DGPDCTTLKEQIC 1145
              G  C  L+   C
Sbjct: 2179 SSGRRCQDLRMSYC 2192



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 87/349 (24%), Positives = 137/349 (39%), Gaps = 68/349 (19%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQR----GEYINGE----CQCNPGWKGKECSLRHDEC-E 943
            C+C  GF  D   + +    C +     GE IN +    CQC  G++    +L   EC +
Sbjct: 605  CECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQS---TLTRTECRD 661

Query: 944  VPDC--NG----HGHCVNGK----CSCVRGYK----GKFCGEID-CPHPTCSGHGFCI-- 986
            + +C  NG    +G C+N      C C  G+     GK C ++D C       +G CI  
Sbjct: 662  IDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINE 721

Query: 987  EGT--CVCKKGWKGADCGTMDKDALQC-LPD-CSGHGTFDVD-TQTCSCH----AKWSGE 1037
            +G+  C+CK G++ A  G   KD  +C  P  C      + D +  C C         G 
Sbjct: 722  DGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGR 781

Query: 1038 DCSKEVCSLEC-GPH--GRCV---------GESCSCAAGWS-GEFCSVRLCDARCAEHGQ 1084
             C        C G +  G+C+          E C  +  ++ GE C              
Sbjct: 782  VCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQAL 841

Query: 1085 CKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD----GPDCTTL 1140
            C +G  +  +G +   C L+  P  C  +G C  +  G ++C C  G++    G +C  +
Sbjct: 842  CSSGPGMTSAGSDINECALD--PDICP-NGICE-NLRGTYKCICNSGYEVDSTGKNCVDI 897

Query: 1141 KE-----QICDDSRDNDKDGLVDCEDPE-CCQSP---ACKSSQLCVSSP 1180
             E      +CD+ +  +  G   C  P+     P    C+    C SSP
Sbjct: 898  NECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP 946



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 95/340 (27%), Positives = 134/340 (39%), Gaps = 65/340 (19%)

Query: 876  HNCPNGCSGKGEC--LMG--HCQCQPGF---GGDDC-SKSVCPV----LCSQRGEYING- 922
            + C     G G C   +G  +C+C  GF     +DC     C      LC + G+ IN  
Sbjct: 2024 NECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLC-RNGQCINTV 2082

Query: 923  ---ECQCNPGWK----GKECSLRHDECEV-PDCNGHGHCVN----GKCSCVRGY--KGKF 968
               +CQCN G++    G+ C +  +EC + P     G C N     +C C  GY  + + 
Sbjct: 2083 GSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEK 2141

Query: 969  CGEID-C-PHPTCSGHGFC--IEGT--CVCKKGWKGADCGTMDKDALQ--CLPD-----C 1015
            C +ID C   P     G C   EG+  C+C +G+  +  G   +D     C        C
Sbjct: 2142 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKC 2201

Query: 1016 SGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWS-GEFCSVRL 1074
            S   + +   Q C C  K  G     E+C  E     R +   C   +G   G   S   
Sbjct: 2202 SSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQI---CPYGSGIIVGPDDSAVD 2258

Query: 1075 CDARCAEHGQCKNGTCLCVSGWNGRHC----TLEGCPRSCAGHGQCRVDND-GRWECKCF 1129
             D  C E   CK+G C+   G     C    TL G    C    +C V N  G   CK  
Sbjct: 2259 MD-ECKEPDVCKHGQCINTDGSYRCECPFGYTLAG--NECVDTDECSVGNPCGNGTCKNV 2315

Query: 1130 DGWDGPDCTTLKEQICDDSRDNDKDGLVDCED-PECCQSP 1168
             G  G +CT      C++    +   ++ CED  EC Q+P
Sbjct: 2316 IG--GFECT------CEEG--FEPGPMMTCEDINECAQNP 2345



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 91/339 (26%), Positives = 133/339 (39%), Gaps = 76/339 (22%)

Query: 902  DDCSKSVCPVLCSQRGEYING----ECQCNPGWKGK---ECSLRHDECEVPDCNGHGHCV 954
            D+C     PV C +  E IN      C C PG++     +C+ R++  E+P+   HG C+
Sbjct: 1941 DECQNG--PV-CQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCI 1997

Query: 955  N--GK--CSCVRGYKGK----FCGEI-DCPHPTCSGHGFCIEG----TCVCKKGW---KG 998
            +  G   C C  G+K       C +I +C    C G+G C        C C  G+     
Sbjct: 1998 DTVGSFYCLCHTGFKTNDDQTMCLDINECERDAC-GNGTCRNTIGSFNCRCNHGFILSHN 2056

Query: 999  ADCGTMDKDALQCLPDC-SGHGTFDVDTQTCSCHAKW----SGEDC-SKEVCSLE---CG 1049
             DC  +D+ A      C +G     V +  C C+  +     G  C     C LE   C 
Sbjct: 2057 NDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCA 2116

Query: 1050 PHGRCV----GESCSCAAGWS--GEFC-SVRLC--DARCAEHGQCKN--GT--CLCVSGW 1096
            P G C        C C  G+S   E C  +  C  +      G C N  G+  CLC  G+
Sbjct: 2117 P-GTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGF 2175

Query: 1097 ----NGRHC---TLEGCPRSCAGHGQC---RVDNDGRWECKCF---DGWDGPD--CTTLK 1141
                +GR C    +  C     G G+C   +  N  + EC C    +GW  P   C T  
Sbjct: 2176 SLSSSGRRCQDLRMSYCYAKFEG-GKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEP 2234

Query: 1142 E----QICDDSR------DNDKDGLVDCEDPECCQSPAC 1170
            +    QIC          D+    + +C++P+ C+   C
Sbjct: 2235 DEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQC 2273



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 85/319 (26%), Positives = 132/319 (41%), Gaps = 68/319 (21%)

Query: 878  CPNG---CSGKGEC--LMG--HCQCQPGFGG--------DDCSKSVCPVLCSQRGEYING 922
            C NG   CS   +C   MG   C C+ G+ G        D+CS+++   LC   G+ +N 
Sbjct: 1498 CSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENL--NLCG-NGQCLNA 1554

Query: 923  ----ECQCNPGW----KGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYK----G 966
                 C+C+ G+     GK C    DEC +P+    G C N     +C C  GY+    G
Sbjct: 1555 PGGYRCECDMGFVPSADGKACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSG 1613

Query: 967  KFCGEI-DCPHPTCSGHGFCIEGTCVCKKGWKGADCG---TMDKDALQCLPDCSGHGTFD 1022
              C ++ +C  PT      CI G CV   G    DC     ++   + C+   SG+   D
Sbjct: 1614 GNCTDVNECLDPTT-----CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLD 1668

Query: 1023 V----DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCS-CAAGWSGEFCSVRLCDA 1077
            +    D    +C +   G   SK  C   C   G+  G  C  C A  + E+    LC  
Sbjct: 1669 IRPRGDNGDTAC-SNEIGVGVSKASC---CCSLGKAWGTPCEMCPAVNTSEY--KILCPG 1722

Query: 1078 RCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                 G+      + V   +   C  +  P  C G G+C ++  G ++C+C  G+   + 
Sbjct: 1723 -----GEGFRPNPITVILEDIDEC--QELPGLCQG-GKC-INTFGSFQCRCPTGYYLNED 1773

Query: 1138 TTLKEQICDDSRDNDKDGL 1156
            T    ++CDD  + +  G+
Sbjct: 1774 T----RVCDDVNECETPGI 1788



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 54/205 (26%), Positives = 74/205 (36%), Gaps = 20/205 (9%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYI-NGECQCNPGWKGKEC 935
            +C   C   G C   HC CQ G+ G  C + VC   C   G  +    C C  G+ G +C
Sbjct: 249  HCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQC 308

Query: 936  --SLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEID--CPHPTCSGHGFCIEGTCV 991
                R   C     N       G+ S +   K   C  +     HP C     C      
Sbjct: 309  ERDYRTGPCFTVISN---QMCQGQLSGIVCTKTLCCATVGRAWGHP-CE---MCPAQPHP 361

Query: 992  CKKGW-KGADCGT-MDKDALQCLPD-CSGHGTFD-VDTQTCSCHAKWSGEDCSKEVCSL- 1046
            C++G+      G   D D  Q +P  C G    + V +  C C A     + S++   + 
Sbjct: 362  CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 421

Query: 1047 ECGP-HGRCVGESCSCAAGWSGEFC 1070
            EC    G C G  C+     S  FC
Sbjct: 422  ECSTIPGICEGGECTNTV--SSYFC 444



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 67/233 (28%), Positives = 93/233 (39%), Gaps = 51/233 (21%)

Query: 926  CNPGW---KGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGH 982
            C  G+   KG +C    DECEV      G C NG C   RG          C  P+    
Sbjct: 1027 CGKGYSRIKGTQCE-DIDECEVFP----GVCKNGLCVNTRG-------SFKCQCPS---- 1070

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
            G  ++ T       +   C    +D    LP    H    +D   CS  A W  E+C  E
Sbjct: 1071 GMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHR---MDACCCSVGAAWGTEEC--E 1125

Query: 1043 VCSLECGPHGRCVGESCSCAAGWSGE--------FCSVRLCDA--RCAEHGQCKN--GT- 1089
             C +   P      E C    G++ +        F  +  C        HG+C+N  G+ 
Sbjct: 1126 ECPMRNTPEYE---ELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSF 1182

Query: 1090 -CLCVSGW----NGRHCT-LEGC---PRSCAGHGQCRVDNDGRWECKCFDGWD 1133
             C C SG+      R+CT ++ C   P  C G GQC V+  G +ECKC +G++
Sbjct: 1183 KCRCDSGFALDSEERNCTDIDECRISPDLC-GRGQC-VNTPGDFECKCDEGYE 1233



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 52/207 (25%), Positives = 78/207 (37%), Gaps = 35/207 (16%)

Query: 957  KCSCVRGYKGKFCGEI----DCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDA 1008
            +C C +G++    GE     +C    C+G G CI      TC C+ G++     T  +D 
Sbjct: 604  RCECNKGFQLDLRGECIDVDECEKNPCAG-GECINNQGSYTCQCRAGYQSTLTRTECRDI 662

Query: 1009 LQCLPD---CSGHGTFDVD-TQTCSC----HAKWSGEDC-SKEVCSL-ECGPHGRCVGE- 1057
             +CL +   C+     + D +  C C    H    G++C   + CS+     +G C+ E 
Sbjct: 663  DECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINED 722

Query: 1058 ---SCSCAAGW----SGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSC 1110
                C C  G+     G +C        C   G C NG C+   G     C   G     
Sbjct: 723  GSFKCICKPGFQLASDGRYCK---DINECETPGICMNGRCVNTDGSYRCEC-FPGLAVGL 778

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             G    RV  D      C+ G+    C
Sbjct: 779  DG----RVCVDTHMRSTCYGGYKRGQC 801



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 44/158 (27%), Positives = 64/158 (40%), Gaps = 26/158 (16%)

Query: 880  NGCSGKGECL-MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLR 938
            +G  GK  C  +  C+     G  +C K    V  +  G +   +C C+PGW G      
Sbjct: 1443 SGKKGKTGCTDINECE----IGAHNCGKHA--VCTNTAGSF---KCSCSPGWIGDGIKCT 1493

Query: 939  H-DECE--VPDCNGHGHCVNG----KCSCVRGYKGK--FCGEID-C-PHPTCSGHGFCIE 987
              DEC      C+ H  C N     +C C  GY G    C ++D C  +    G+G C+ 
Sbjct: 1494 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLN 1553

Query: 988  G----TCVCKKGWKGADCGTMDKDALQC-LPDCSGHGT 1020
                  C C  G+  +  G   +D  +C LP+    GT
Sbjct: 1554 APGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGT 1591



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 69/284 (24%), Positives = 110/284 (38%), Gaps = 52/284 (18%)

Query: 892  HCQCQPGFGGDDCSKSVCPVL--CSQRGEYING---------ECQCNPGWK----GKECS 936
            HC C  GF      K+ C  +  CS R   +NG         +C C PG++    G+ C 
Sbjct: 685  HCVCNAGFHVTRDGKN-CEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK 743

Query: 937  LRHDECEVPDCNGHGHCVNG----KCSC----VRGYKGKFCGEIDCPHPTCSG---HGFC 985
               +ECE P    +G CVN     +C C      G  G+ C +      TC G    G C
Sbjct: 744  -DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHM-RSTCYGGYKRGQC 801

Query: 986  IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWS-GEDCSKEVC 1044
            I+         +     T       C P C    + +      S     S G D ++   
Sbjct: 802  IKPLFGAVTKSECCCASTEYAFGEPCQP-CPAQNSAEYQALCSSGPGMTSAGSDINECAL 860

Query: 1045 SLECGPHGRCVG----ESCSCAAGW----SGEFC-SVRLC--DARCAEHGQCKNG----T 1089
              +  P+G C        C C +G+    +G+ C  +  C  ++   ++GQC+N      
Sbjct: 861  DPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFV 920

Query: 1090 CLCVSGW----NGRHC-TLEGCPRSCAGHGQCRVDNDGRWECKC 1128
            C C  G+    + + C  ++ C  S   +G C+ ++ G + C+C
Sbjct: 921  CTCPKGFIYKPDLKTCEDIDECESSPCINGVCK-NSPGSFICEC 963



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 71/282 (25%), Positives = 99/282 (35%), Gaps = 62/282 (21%)

Query: 886  GECLMG----HCQCQPGFGGD----------DCSKSV--CPVLCSQ-RGEYINGECQCNP 928
            GEC+      HC C+ G+  D          +C+++   C  +C    G Y   +C C  
Sbjct: 2547 GECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSY---QCSCPK 2603

Query: 929  GW----KGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEIDCPHPT-- 978
            G+     G+ C    DEC     N    CVN      C C  G+       ID    T  
Sbjct: 2604 GYILQEDGRSCK-DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSD 2662

Query: 979  ---CSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD--CSGHGTFD-VDTQTC 1028
               C   G C       TC C++G+     G+  +D  +C  +  C  HG  + +    C
Sbjct: 2663 INLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQ-HGCQNIIGGYRC 2721

Query: 1029 SC------HAKWS-----GEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDA 1077
            SC      H +W+      E  S  +C      H       C C AG+  E  S      
Sbjct: 2722 SCPQGYLQHYQWNQCVDENECLSAHICG-GASCHNTLGSYKCMCPAGFQYEQFS-----G 2775

Query: 1078 RCAEHGQCKNGTCLCVSGW-NGRHCTLEGCPRSC--AGHGQC 1116
             C +  +C +    C  G  N     L GCP      G G C
Sbjct: 2776 GCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHC 2817


>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
          Length = 2871

 Score = 70.9 bits (166), Expect = 6e-11
 Identities = 93/338 (27%), Positives = 139/338 (41%), Gaps = 69/338 (20%)

Query: 887  ECLMGHCQCQPGFGG----DDCSKS--VCPV--LCSQRGEYINGECQCNPGWKGKECSL- 937
            EC  GH Q  P        ++C  S  +CP     +  G+Y   +C CNPG+      L 
Sbjct: 1139 ECPPGH-QLSPNISACIDINECELSAHLCPNGRCVNLIGKY---QCACNPGYHSTPDRLF 1194

Query: 938  --RHDECEVPDCNGHGHCVNGK----CSCVRGYK----GKFCGEID-CP-HPTCSGHGFC 985
                DEC + +      C N +    CSC  G+      + C +ID C  +P     G C
Sbjct: 1195 CVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC 1254

Query: 986  I----EGTCVCKKGWKGADCGTMDKDALQC--LPDCSGHGTFDVDTQT--CSCHAKWSGE 1037
                 E  C+C  G+  ++      D  +C   P+    GT +    +  C C   +SG+
Sbjct: 1255 TNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGK 1314

Query: 1038 D----CSK----EVCSLECGPHGRCVGES----CSCAAGWSGEFCSVRLCDA------RC 1079
                 C+     E+ +  CG H  C   +    CSC+ GW G+       D        C
Sbjct: 1315 KGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMC 1374

Query: 1080 AEHGQCKN--GT--CLCVSGW--NGRHCT-LEGCPR--SCAGHGQCRVDNDGRWECKCFD 1130
            ++H  CKN  G+  CLC  G+  +G  CT L+ C    +  G+GQC ++  G + C+C  
Sbjct: 1375 SQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQC-LNAPGGYRCECDM 1433

Query: 1131 GW----DGPDCTTLKE----QICDDSRDNDKDGLVDCE 1160
            G+    DG  C  + E     IC     ++  GL  CE
Sbjct: 1434 GFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCE 1471



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 35/106 (33%), Positives = 46/106 (43%), Gaps = 9/106 (8%)

Query: 1036 GEDCSKEVCSLECGPHGRCVGES-CSCAAGWSGEFC---SVRLCDARCAEHGQCKNGTCL 1091
            G  C   +C   CG  G C   + C+C +G     C   S++ C+ RC   G C +  CL
Sbjct: 77   GNQCIVPICRHSCGD-GFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCL 135

Query: 1092 CVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C  G+ G HC    C   C   G+C   N     C C  G+ GP C
Sbjct: 136  CQKGYIGTHCGQPVCESGCLNGGRCVAPN----RCACTYGFTGPQC 177



 Score = 65.7 bits (153), Expect = 2e-09
 Identities = 65/240 (27%), Positives = 84/240 (35%), Gaps = 39/240 (16%)

Query: 895  CQPGF----GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH-DECEVPDCNG 949
            C PG+    GG+ C   +C   C          C C  G     C  R    C +   NG
Sbjct: 67   CCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNG 126

Query: 950  HGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDA 1008
             G C +  C C +GY G  CG+  C    C   G C+    C C  G+ G  C   D   
Sbjct: 127  -GSCSDDHCLCQKGYIGTHCGQPVC-ESGCLNGGRCVAPNRCACTYGFTGPQC-ERDYRT 183

Query: 1009 LQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE 1068
              C    S             C  + SG  C+K++C   C   GR  G  C        E
Sbjct: 184  GPCFTVISNQ----------MCQGQLSGIVCTKQLC---CATVGRAWGHPC--------E 222

Query: 1069 FCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKC 1128
             C  +    R       + G C  V       C  +  P  C G G C ++  G +ECKC
Sbjct: 223  MCPAQPHPCRRGFIPNIRTGACQDVD-----EC--QAIPGLCQG-GNC-INTVGSFECKC 273



 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 68/254 (26%), Positives = 106/254 (41%), Gaps = 50/254 (19%)

Query: 940  DECEV-PDCNGHGHCVNG----KCSCVRGYKGKFCGEI----DCPH-PTCSGHGFCIEGT 989
            DEC+  P C  +  C+N     +C C  GY+    G+     +C   P    HG CI+  
Sbjct: 1810 DECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTV 1869

Query: 990  ----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKW---SGEDC- 1039
                C+C  G+K  D  TM  D  +C  D  G+GT    + +  C C+  +      DC 
Sbjct: 1870 GSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCI 1929

Query: 1040 SKEVCSLECG---PHGRCVGE----SCSCAAGW----SGEFC-SVRLC--DARCAEHGQC 1085
              + C+   G    +G+C+       C C  G+     G  C  +  C  + R    G C
Sbjct: 1930 DVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTC 1989

Query: 1086 KN--GT--CLCVSGWN--GRHC-TLEGC---PRSCAGHGQCRVDNDGRWECKCFDGW--- 1132
            +N  G+  C+C  G++     C  ++ C   P  CA  G C  + +G ++C C +G+   
Sbjct: 1990 QNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICA-LGTCS-NTEGSFKCLCPEGFSLS 2047

Query: 1133 -DGPDCTTLKEQIC 1145
              G  C  L+   C
Sbjct: 2048 SSGRRCQDLRMSYC 2061



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 87/349 (24%), Positives = 137/349 (39%), Gaps = 68/349 (19%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQR----GEYINGE----CQCNPGWKGKECSLRHDEC-E 943
            C+C  GF  D   + +    C +     GE IN +    CQC  G++    +L   EC +
Sbjct: 474  CECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCRAGYQS---TLTRTECRD 530

Query: 944  VPDC--NG----HGHCVNGK----CSCVRGYK----GKFCGEID-CPHPTCSGHGFCI-- 986
            + +C  NG    +G C+N      C C  G+     GK C ++D C       +G CI  
Sbjct: 531  IDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINE 590

Query: 987  EGT--CVCKKGWKGADCGTMDKDALQC-LPD-CSGHGTFDVD-TQTCSCH----AKWSGE 1037
            +G+  C+CK G++ A  G   KD  +C  P  C      + D +  C C         G 
Sbjct: 591  DGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGR 650

Query: 1038 DCSKEVCSLEC-GPH--GRCV---------GESCSCAAGWS-GEFCSVRLCDARCAEHGQ 1084
             C        C G +  G+C+          E C  +  ++ GE C              
Sbjct: 651  VCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQAL 710

Query: 1085 CKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWD----GPDCTTL 1140
            C +G  +  +G +   C L+  P  C  +G C  +  G ++C C  G++    G +C  +
Sbjct: 711  CSSGPGMTSAGSDINECALD--PDICP-NGICE-NLRGTYKCICNSGYEVDSTGKNCVDI 766

Query: 1141 KE-----QICDDSRDNDKDGLVDCEDPE-CCQSP---ACKSSQLCVSSP 1180
             E      +CD+ +  +  G   C  P+     P    C+    C SSP
Sbjct: 767  NECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSP 815



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 95/340 (27%), Positives = 134/340 (39%), Gaps = 65/340 (19%)

Query: 876  HNCPNGCSGKGEC--LMG--HCQCQPGF---GGDDC-SKSVCPV----LCSQRGEYING- 922
            + C     G G C   +G  +C+C  GF     +DC     C      LC + G+ IN  
Sbjct: 1893 NECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLC-RNGQCINTV 1951

Query: 923  ---ECQCNPGWK----GKECSLRHDECEV-PDCNGHGHCVN----GKCSCVRGY--KGKF 968
               +CQCN G++    G+ C +  +EC + P     G C N     +C C  GY  + + 
Sbjct: 1952 GSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEK 2010

Query: 969  CGEID-C-PHPTCSGHGFC--IEGT--CVCKKGWKGADCGTMDKDALQ--CLPD-----C 1015
            C +ID C   P     G C   EG+  C+C +G+  +  G   +D     C        C
Sbjct: 2011 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKC 2070

Query: 1016 SGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWS-GEFCSVRL 1074
            S   + +   Q C C  K  G     E+C  E     R +   C   +G   G   S   
Sbjct: 2071 SSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQI---CPYGSGIIVGPDDSAVD 2127

Query: 1075 CDARCAEHGQCKNGTCLCVSGWNGRHC----TLEGCPRSCAGHGQCRVDND-GRWECKCF 1129
             D  C E   CK+G C+   G     C    TL G    C    +C V N  G   CK  
Sbjct: 2128 MD-ECKEPDVCKHGQCINTDGSYRCECPFGYTLAG--NECVDTDECSVGNPCGNGTCKNV 2184

Query: 1130 DGWDGPDCTTLKEQICDDSRDNDKDGLVDCED-PECCQSP 1168
             G  G +CT      C++    +   ++ CED  EC Q+P
Sbjct: 2185 IG--GFECT------CEEG--FEPGPMMTCEDINECAQNP 2214



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 91/339 (26%), Positives = 133/339 (39%), Gaps = 76/339 (22%)

Query: 902  DDCSKSVCPVLCSQRGEYING----ECQCNPGWKGK---ECSLRHDECEVPDCNGHGHCV 954
            D+C     PV C +  E IN      C C PG++     +C+ R++  E+P+   HG C+
Sbjct: 1810 DECQNG--PV-CQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCI 1866

Query: 955  N--GK--CSCVRGYKGK----FCGEI-DCPHPTCSGHGFCIEG----TCVCKKGW---KG 998
            +  G   C C  G+K       C +I +C    C G+G C        C C  G+     
Sbjct: 1867 DTVGSFYCLCHTGFKTNDDQTMCLDINECERDAC-GNGTCRNTIGSFNCRCNHGFILSHN 1925

Query: 999  ADCGTMDKDALQCLPDC-SGHGTFDVDTQTCSCHAKW----SGEDC-SKEVCSLE---CG 1049
             DC  +D+ A      C +G     V +  C C+  +     G  C     C LE   C 
Sbjct: 1926 NDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCA 1985

Query: 1050 PHGRCV----GESCSCAAGWS--GEFC-SVRLC--DARCAEHGQCKN--GT--CLCVSGW 1096
            P G C        C C  G+S   E C  +  C  +      G C N  G+  CLC  G+
Sbjct: 1986 P-GTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGF 2044

Query: 1097 ----NGRHC---TLEGCPRSCAGHGQC---RVDNDGRWECKCF---DGWDGPD--CTTLK 1141
                +GR C    +  C     G G+C   +  N  + EC C    +GW  P   C T  
Sbjct: 2045 SLSSSGRRCQDLRMSYCYAKFEG-GKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEP 2103

Query: 1142 E----QICDDSR------DNDKDGLVDCEDPECCQSPAC 1170
            +    QIC          D+    + +C++P+ C+   C
Sbjct: 2104 DEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQC 2142



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 85/319 (26%), Positives = 132/319 (41%), Gaps = 68/319 (21%)

Query: 878  CPNG---CSGKGEC--LMG--HCQCQPGFGG--------DDCSKSVCPVLCSQRGEYING 922
            C NG   CS   +C   MG   C C+ G+ G        D+CS+++   LC   G+ +N 
Sbjct: 1367 CSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENL--NLCG-NGQCLNA 1423

Query: 923  ----ECQCNPGW----KGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYK----G 966
                 C+C+ G+     GK C    DEC +P+    G C N     +C C  GY+    G
Sbjct: 1424 PGGYRCECDMGFVPSADGKACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSG 1482

Query: 967  KFCGEI-DCPHPTCSGHGFCIEGTCVCKKGWKGADCG---TMDKDALQCLPDCSGHGTFD 1022
              C ++ +C  PT      CI G CV   G    DC     ++   + C+   SG+   D
Sbjct: 1483 GNCTDVNECLDPTT-----CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLD 1537

Query: 1023 V----DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCS-CAAGWSGEFCSVRLCDA 1077
            +    D    +C +   G   SK  C   C   G+  G  C  C A  + E+    LC  
Sbjct: 1538 IRPRGDNGDTAC-SNEIGVGVSKASC---CCSLGKAWGTPCEMCPAVNTSEY--KILCPG 1591

Query: 1078 RCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                 G+      + V   +   C  +  P  C G G+C ++  G ++C+C  G+   + 
Sbjct: 1592 -----GEGFRPNPITVILEDIDEC--QELPGLCQG-GKC-INTFGSFQCRCPTGYYLNED 1642

Query: 1138 TTLKEQICDDSRDNDKDGL 1156
            T    ++CDD  + +  G+
Sbjct: 1643 T----RVCDDVNECETPGI 1657



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 54/205 (26%), Positives = 74/205 (36%), Gaps = 20/205 (9%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYI-NGECQCNPGWKGKEC 935
            +C   C   G C   HC CQ G+ G  C + VC   C   G  +    C C  G+ G +C
Sbjct: 118  HCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQC 177

Query: 936  --SLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEID--CPHPTCSGHGFCIEGTCV 991
                R   C     N       G+ S +   K   C  +     HP C     C      
Sbjct: 178  ERDYRTGPCFTVISN---QMCQGQLSGIVCTKQLCCATVGRAWGHP-CE---MCPAQPHP 230

Query: 992  CKKGW-KGADCGT-MDKDALQCLPD-CSGHGTFD-VDTQTCSCHAKWSGEDCSKEVCSL- 1046
            C++G+      G   D D  Q +P  C G    + V +  C C A     + S++   + 
Sbjct: 231  CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290

Query: 1047 ECGP-HGRCVGESCSCAAGWSGEFC 1070
            EC    G C G  C+     S  FC
Sbjct: 291  ECSTIPGICEGGECTNTV--SSYFC 313



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 67/233 (28%), Positives = 93/233 (39%), Gaps = 51/233 (21%)

Query: 926  CNPGW---KGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGH 982
            C  G+   KG +C    DECEV      G C NG C   RG          C  P+    
Sbjct: 896  CGKGYSRIKGTQCE-DIDECEVFP----GVCKNGLCVNTRG-------SFKCQCPS---- 939

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
            G  ++ T       +   C    +D    LP    H    +D   CS  A W  E+C  E
Sbjct: 940  GMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHR---MDACCCSVGAAWGTEEC--E 994

Query: 1043 VCSLECGPHGRCVGESCSCAAGWSGE--------FCSVRLCDA--RCAEHGQCKN--GT- 1089
             C +   P      E C    G++ +        F  +  C        HG+C+N  G+ 
Sbjct: 995  ECPMRNTPEYE---ELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSF 1051

Query: 1090 -CLCVSGW----NGRHCT-LEGC---PRSCAGHGQCRVDNDGRWECKCFDGWD 1133
             C C SG+      R+CT ++ C   P  C G GQC V+  G +ECKC +G++
Sbjct: 1052 KCRCDSGFALDSEERNCTDIDECRISPDLC-GRGQC-VNTPGDFECKCDEGYE 1102



 Score = 44.0 bits (99), Expect = 0.008
 Identities = 52/207 (25%), Positives = 78/207 (37%), Gaps = 35/207 (16%)

Query: 957  KCSCVRGYKGKFCGEI----DCPHPTCSGHGFCIEG----TCVCKKGWKGADCGTMDKDA 1008
            +C C +G++    GE     +C    C+G G CI      TC C+ G++     T  +D 
Sbjct: 473  RCECNKGFQLDLRGECIDVDECEKNPCAG-GECINNQGSYTCQCRAGYQSTLTRTECRDI 531

Query: 1009 LQCLPD---CSGHGTFDVD-TQTCSC----HAKWSGEDC-SKEVCSL-ECGPHGRCVGE- 1057
             +CL +   C+     + D +  C C    H    G++C   + CS+     +G C+ E 
Sbjct: 532  DECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINED 591

Query: 1058 ---SCSCAAGW----SGEFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSC 1110
                C C  G+     G +C        C   G C NG C+   G     C   G     
Sbjct: 592  GSFKCICKPGFQLASDGRYCK---DINECETPGICMNGRCVNTDGSYRCEC-FPGLAVGL 647

Query: 1111 AGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             G    RV  D      C+ G+    C
Sbjct: 648  DG----RVCVDTHMRSTCYGGYKRGQC 670



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 44/158 (27%), Positives = 64/158 (40%), Gaps = 26/158 (16%)

Query: 880  NGCSGKGECL-MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLR 938
            +G  GK  C  +  C+     G  +C K    V  +  G +   +C C+PGW G      
Sbjct: 1312 SGKKGKTGCTDINECE----IGAHNCGKHA--VCTNTAGSF---KCSCSPGWIGDGIKCT 1362

Query: 939  H-DECE--VPDCNGHGHCVNG----KCSCVRGYKGK--FCGEID-C-PHPTCSGHGFCIE 987
              DEC      C+ H  C N     +C C  GY G    C ++D C  +    G+G C+ 
Sbjct: 1363 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLN 1422

Query: 988  G----TCVCKKGWKGADCGTMDKDALQC-LPDCSGHGT 1020
                  C C  G+  +  G   +D  +C LP+    GT
Sbjct: 1423 APGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGT 1460



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 69/284 (24%), Positives = 110/284 (38%), Gaps = 52/284 (18%)

Query: 892  HCQCQPGFGGDDCSKSVCPVL--CSQRGEYING---------ECQCNPGWK----GKECS 936
            HC C  GF      K+ C  +  CS R   +NG         +C C PG++    G+ C 
Sbjct: 554  HCVCNAGFHVTRDGKN-CEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK 612

Query: 937  LRHDECEVPDCNGHGHCVNG----KCSC----VRGYKGKFCGEIDCPHPTCSG---HGFC 985
               +ECE P    +G CVN     +C C      G  G+ C +      TC G    G C
Sbjct: 613  -DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHM-RSTCYGGYKRGQC 670

Query: 986  IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWS-GEDCSKEVC 1044
            I+         +     T       C P C    + +      S     S G D ++   
Sbjct: 671  IKPLFGAVTKSECCCASTEYAFGEPCQP-CPAQNSAEYQALCSSGPGMTSAGSDINECAL 729

Query: 1045 SLECGPHGRCVG----ESCSCAAGW----SGEFC-SVRLC--DARCAEHGQCKNG----T 1089
              +  P+G C        C C +G+    +G+ C  +  C  ++   ++GQC+N      
Sbjct: 730  DPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFV 789

Query: 1090 CLCVSGW----NGRHC-TLEGCPRSCAGHGQCRVDNDGRWECKC 1128
            C C  G+    + + C  ++ C  S   +G C+ ++ G + C+C
Sbjct: 790  CTCPKGFIYKPDLKTCEDIDECESSPCINGVCK-NSPGSFICEC 832



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 71/282 (25%), Positives = 99/282 (35%), Gaps = 62/282 (21%)

Query: 886  GECLMG----HCQCQPGFGGD----------DCSKSV--CPVLCSQ-RGEYINGECQCNP 928
            GEC+      HC C+ G+  D          +C+++   C  +C    G Y   +C C  
Sbjct: 2416 GECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSY---QCSCPK 2472

Query: 929  GW----KGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEIDCPHPT-- 978
            G+     G+ C    DEC     N    CVN      C C  G+       ID    T  
Sbjct: 2473 GYILQEDGRSCK-DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSD 2531

Query: 979  ---CSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD--CSGHGTFD-VDTQTC 1028
               C   G C       TC C++G+     G+  +D  +C  +  C  HG  + +    C
Sbjct: 2532 INLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQ-HGCQNIIGGYRC 2590

Query: 1029 SC------HAKWS-----GEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDA 1077
            SC      H +W+      E  S  +C      H       C C AG+  E  S      
Sbjct: 2591 SCPQGYLQHYQWNQCVDENECLSAHICG-GASCHNTLGSYKCMCPAGFQYEQFS-----G 2644

Query: 1078 RCAEHGQCKNGTCLCVSGW-NGRHCTLEGCPRSC--AGHGQC 1116
             C +  +C +    C  G  N     L GCP      G G C
Sbjct: 2645 GCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHC 2686


>AF075240-1|AAD19336.1|  850|Homo sapiens SLIT1 protein protein.
          Length = 850

 Score = 70.9 bits (166), Expect = 6e-11
 Identities = 60/205 (29%), Positives = 86/205 (41%), Gaps = 29/205 (14%)

Query: 861  PQEISFVALVAEEMTHNCPN-GCSGKGECLMGHCQCQPGFGGDDCSKSVCPVL------- 912
            P +I+ VA     ++  C N G   +    +  C C   + G DC+  +   +       
Sbjct: 335  PVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHG 394

Query: 913  --CSQRGEYING-ECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYK 965
              C     + +G  C C  G++G+ C +  D+CE  DC  +  CV+G     C C   Y 
Sbjct: 395  GTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYT 454

Query: 966  GKFCGE-IDCPHP---TCSGHGFCI---EG-TCVCKKGWKGADCGTMDKDALQCLPDCSG 1017
            G+ C E ID   P    C     CI   +G +C C  G+ G  C T D D   C+     
Sbjct: 455  GELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCET-DND--DCVAHKCR 511

Query: 1018 HGTFDVDT---QTCSCHAKWSGEDC 1039
            HG   VDT    TC+C   +SG  C
Sbjct: 512  HGAQCVDTINGYTCTCPQGFSGPFC 536



 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 50/192 (26%), Positives = 73/192 (38%), Gaps = 30/192 (15%)

Query: 974  CPHPTCSGHGFCIEGT-----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDV----- 1023
            C    C  +G C +       C C   +KG DC       +Q    C   GT  +     
Sbjct: 347  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQ--NPCQHGGTCHLSDSHK 404

Query: 1024 DTQTCSCHAKWSGEDC--SKEVCS-LECGPHGRCV----GESCSCAAGWSGEFCS--VRL 1074
            D  +CSC   + G+ C  + + C   +C  +  CV       C C   ++GE C   +  
Sbjct: 405  DGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDH 464

Query: 1075 CDAR---CAEHGQC----KNGTCLCVSGWNGRHCTLEG--CPRSCAGHGQCRVDNDGRWE 1125
            C      C    +C    K  +C CV G++G+ C  +   C      HG   VD    + 
Sbjct: 465  CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 524

Query: 1126 CKCFDGWDGPDC 1137
            C C  G+ GP C
Sbjct: 525  CTCPQGFSGPFC 536



 Score = 57.6 bits (133), Expect = 6e-07
 Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 17/98 (17%)

Query: 1024 DTQTCSCHAKWSGEDCSKEV---CSLECGPHGRCV--GES--CSCAAGWSGEFC-----S 1071
            D+  C C   W+G  C +E    C      HG+CV  G S  C CA G+ G+ C     S
Sbjct: 676  DSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDS 735

Query: 1072 VRLCDARCAEHGQCKNGT-----CLCVSGWNGRHCTLE 1104
               C A    HGQC         CLC  G++G HC  E
Sbjct: 736  ANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE 773



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 48/196 (24%), Positives = 73/196 (37%), Gaps = 28/196 (14%)

Query: 1011 CLPD-CSGHGTFD---VDTQTCSCHAKWSGEDCSKEVCSL---ECGPHGRCV-------G 1056
            CL   C  +GT     V+   C+C   + G+DC+  + +     C   G C        G
Sbjct: 347  CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 406

Query: 1057 ESCSCAAGWSGEFCSVRLCDAR---CAEHGQCKNG----TCLCVSGWNGRHC--TLEGCP 1107
             SCSC  G+ G+ C +   D     C  +  C +G     C+C   + G  C   ++ C 
Sbjct: 407  FSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV 466

Query: 1108 RS---CAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDSRDNDKDGLVDCEDPEC 1164
                 C    +C +  D  + C+C  G+ G  C T  +  C   +       VD  +   
Sbjct: 467  PELNLCQHEAKC-IPLDKGFSCECVPGYSGKLCETDNDD-CVAHKCRHGAQCVDTINGYT 524

Query: 1165 CQSPACKSSQLCVSSP 1180
            C  P   S   C   P
Sbjct: 525  CTCPQGFSGPFCEHPP 540



 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 14/92 (15%)

Query: 1059 CSCAAGWSGEFCSVRLCDA----RCAEHGQC-KNGT---CLCVSGWNGRHC-----TLEG 1105
            C C  GW+G  C     D     RC  HG+C   GT   C C  G+ G  C     +   
Sbjct: 680  CECRPGWTGPLCDQEARDPCLGHRC-HHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANA 738

Query: 1106 CPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C      HGQC + + G   C C  G+ G  C
Sbjct: 739  CSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 770



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 31/92 (33%), Positives = 38/92 (41%), Gaps = 15/92 (16%)

Query: 924  CQCNPGWKGKECSLR-HDECEVPDCNGHGHCV----NGKCSCVRGYKGKFCGEIDCPHPT 978
            C+C PGW G  C     D C    C+ HG CV    +  C C  GY G  C   +     
Sbjct: 680  CECRPGWTGPLCDQEARDPCLGHRCH-HGKCVATGTSYMCKCAEGYGGDLCDNKNDSANA 738

Query: 979  CSG----HGFCI-----EGTCVCKKGWKGADC 1001
            CS     HG C      E  C+C+ G+ G  C
Sbjct: 739  CSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 770



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 39/115 (33%), Positives = 46/115 (40%), Gaps = 21/115 (18%)

Query: 974  CPHPTCSGHGFC--IEG---TCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQT- 1027
            C   T   HG C  +E     C C+ GW G  C    +D   CL     HG   V T T 
Sbjct: 659  CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARD--PCLGHRCHHGKC-VATGTS 715

Query: 1028 --CSCHAKWSGEDC-----SKEVCSLECGPHGRC----VGES-CSCAAGWSGEFC 1070
              C C   + G+ C     S   CS     HG+C     GE  C C  G+SGE C
Sbjct: 716  YMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 770



 Score = 38.3 bits (85), Expect = 0.42
 Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 13/71 (18%)

Query: 876 HNCPNG-CSGKGECLMGHCQCQPGFGGDDC-----SKSVCPVLCSQRGE-YIN--GE--C 924
           H C +G C   G   M  C+C  G+GGD C     S + C       G+ +I+  GE  C
Sbjct: 702 HRCHHGKCVATGTSYM--CKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYC 759

Query: 925 QCNPGWKGKEC 935
            C PG+ G+ C
Sbjct: 760 LCQPGFSGEHC 770



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 35/139 (25%), Positives = 59/139 (42%), Gaps = 25/139 (17%)

Query: 893  CQCQPGFGGDDCSKSVCPVLCSQR---GEYI----NGECQCNPGWKGKECSLRHDE---C 942
            C+C+PG+ G  C +         R   G+ +    +  C+C  G+ G  C  ++D    C
Sbjct: 680  CECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 739

Query: 943  EVPDCNGHGHC-VNGK----CSCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWK 997
                C+ HG C ++ +    C C  G+ G+ C +    +P C G    +      +KG+ 
Sbjct: 740  SAFKCH-HGQCHISDQGEPYCLCQPGFSGEHCQQ---ENP-CLGQ--VVREVIRRQKGY- 791

Query: 998  GADCGTMDK-DALQCLPDC 1015
             A C T  K   ++C   C
Sbjct: 792  -ASCATASKVPIMECRGGC 809


>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
          Length = 2871

 Score = 70.9 bits (166), Expect = 6e-11
 Identities = 93/338 (27%), Positives = 139/338 (41%), Gaps = 69/338 (20%)

Query: 887  ECLMGHCQCQPGFGG----DDCSKS--VCPV--LCSQRGEYINGECQCNPGWKGKECSL- 937
            EC  GH Q  P        ++C  S  +CP     +  G+Y   +C CNPG+      L 
Sbjct: 1139 ECPPGH-QLSPNISACIDINECELSAHLCPNGRCVNLIGKY---QCACNPGYHSTPDRLF 1194

Query: 938  --RHDECEVPDCNGHGHCVNGK----CSCVRGYK----GKFCGEID-CP-HPTCSGHGFC 985
                DEC + +      C N +    CSC  G+      + C +ID C  +P     G C
Sbjct: 1195 CVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC 1254

Query: 986  I----EGTCVCKKGWKGADCGTMDKDALQC--LPDCSGHGTFDVDTQT--CSCHAKWSGE 1037
                 E  C+C  G+  ++      D  +C   P+    GT +    +  C C   +SG+
Sbjct: 1255 TNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGK 1314

Query: 1038 D----CSK----EVCSLECGPHGRCVGES----CSCAAGWSGEFCSVRLCDA------RC 1079
                 C+     E+ +  CG H  C   +    CSC+ GW G+       D        C
Sbjct: 1315 KGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMC 1374

Query: 1080 AEHGQCKN--GT--CLCVSGW--NGRHCT-LEGCPR--SCAGHGQCRVDNDGRWECKCFD 1130
            ++H  CKN  G+  CLC  G+  +G  CT L+ C    +  G+GQC ++  G + C+C  
Sbjct: 1375 SQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQC-LNAPGGYRCECDM 1433

Query: 1131 GW----DGPDCTTLKE----QICDDSRDNDKDGLVDCE 1160
            G+    DG  C  + E     IC     ++  GL  CE
Sbjct: 1434 GFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCE 1471



 Score = 68.9 bits (161), Expect = 3e-10
 Identities = 35/106 (33%), Positives = 46/106 (43%), Gaps = 9/106 (8%)

Query: 1036 GEDCSKEVCSLECGPHGRCVGES-CSCAAGWSGEFC---SVRLCDARCAEHGQCKNGTCL 1091
            G  C   +C   CG  G C   + C+C +G     C   S++ C+ RC   G C +  CL
Sbjct: 77   GNQCIVPICRHSCGD-GFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDHCL 135

Query: 1092 CVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
            C  G+ G HC    C   C   G+C   N     C C  G+ GP C
Sbjct: 136  CQKGYIGTHCGQPVCESGCLNGGRCVAPN----RCACTYGFTGPQC 177



 Score = 64.5 bits (150), Expect = 6e-09
 Identities = 65/240 (27%), Positives = 83/240 (34%), Gaps = 39/240 (16%)

Query: 895  CQPGF----GGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRH-DECEVPDCNG 949
            C PG+    GG+ C   +C   C          C C  G     C  R    C +   NG
Sbjct: 67   CCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNG 126

Query: 950  HGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDA 1008
             G C +  C C +GY G  CG+  C    C   G C+    C C  G+ G  C   D   
Sbjct: 127  -GSCSDDHCLCQKGYIGTHCGQPVC-ESGCLNGGRCVAPNRCACTYGFTGPQC-ERDYRT 183

Query: 1009 LQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWSGE 1068
              C    S             C  + SG  C+K +C   C   GR  G  C        E
Sbjct: 184  GPCFTVISNQ----------MCQGQLSGIVCTKTLC---CATVGRAWGHPC--------E 222

Query: 1069 FCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKC 1128
             C  +    R       + G C  V       C  +  P  C G G C ++  G +ECKC
Sbjct: 223  MCPAQPHPCRRGFIPNIRTGACQDVD-----EC--QAIPGLCQG-GNC-INTVGSFECKC 273



 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 68/254 (26%), Positives = 106/254 (41%), Gaps = 50/254 (19%)

Query: 940  DECEV-PDCNGHGHCVNG----KCSCVRGYKGKFCGEI----DCPH-PTCSGHGFCIEGT 989
            DEC+  P C  +  C+N     +C C  GY+    G+     +C   P    HG CI+  
Sbjct: 1810 DECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTV 1869

Query: 990  ----CVCKKGWKGADCGTMDKDALQCLPDCSGHGTF--DVDTQTCSCHAKW---SGEDC- 1039
                C+C  G+K  D  TM  D  +C  D  G+GT    + +  C C+  +      DC 
Sbjct: 1870 GSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCI 1929

Query: 1040 SKEVCSLECG---PHGRCVGE----SCSCAAGW----SGEFC-SVRLC--DARCAEHGQC 1085
              + C+   G    +G+C+       C C  G+     G  C  +  C  + R    G C
Sbjct: 1930 DVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTC 1989

Query: 1086 KN--GT--CLCVSGWN--GRHC-TLEGC---PRSCAGHGQCRVDNDGRWECKCFDGW--- 1132
            +N  G+  C+C  G++     C  ++ C   P  CA  G C  + +G ++C C +G+   
Sbjct: 1990 QNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICA-LGTCS-NTEGSFKCLCPEGFSLS 2047

Query: 1133 -DGPDCTTLKEQIC 1145
              G  C  L+   C
Sbjct: 2048 SSGRRCQDLRMSYC 2061



 Score = 54.0 bits (124), Expect = 8e-06
 Identities = 93/366 (25%), Positives = 143/366 (39%), Gaps = 73/366 (19%)

Query: 878  CPNG-C-SGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQR----GEYINGE----CQCN 927
            C NG C    G C    C+C  GF  D   + +    C +     GE IN +    CQC 
Sbjct: 460  CQNGRCIPTPGSC---RCECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQCR 516

Query: 928  PGWKGKECSLRHDEC-EVPDC--NG----HGHCVNGK----CSCVRGYK----GKFCGEI 972
             G++    +L   EC ++ +C  NG    +G C+N      C C  G+     GK C ++
Sbjct: 517  AGYQS---TLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDM 573

Query: 973  D-CPHPTCSGHGFCI--EGT--CVCKKGWKGADCGTMDKDALQC-LPD-CSGHGTFDVD- 1024
            D C       +G CI  +G+  C+CK G++ A  G   KD  +C  P  C      + D 
Sbjct: 574  DECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDG 633

Query: 1025 TQTCSCH----AKWSGEDCSKEVCSLEC-GPH--GRCV---------GESCSCAAGWS-G 1067
            +  C C         G  C        C G +  G+C+          E C  +  ++ G
Sbjct: 634  SYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFG 693

Query: 1068 EFCSVRLCDARCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECK 1127
            E C              C +G  +  +G +   C L+  P  C  +G C  +  G ++C 
Sbjct: 694  EPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALD--PDICP-NGICE-NLRGTYKCI 749

Query: 1128 CFDGWD----GPDCTTLKE-----QICDDSRDNDKDGLVDCEDPE-CCQSP---ACKSSQ 1174
            C  G++    G +C  + E      +CD+ +  +  G   C  P+     P    C+   
Sbjct: 750  CNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID 809

Query: 1175 LCVSSP 1180
             C SSP
Sbjct: 810  ECESSP 815



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 91/339 (26%), Positives = 133/339 (39%), Gaps = 76/339 (22%)

Query: 902  DDCSKSVCPVLCSQRGEYING----ECQCNPGWKGK---ECSLRHDECEVPDCNGHGHCV 954
            D+C     PV C +  E IN      C C PG++     +C+ R++  E+P+   HG C+
Sbjct: 1810 DECQNG--PV-CQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCI 1866

Query: 955  N--GK--CSCVRGYKGK----FCGEI-DCPHPTCSGHGFCIEG----TCVCKKGW---KG 998
            +  G   C C  G+K       C +I +C    C G+G C        C C  G+     
Sbjct: 1867 DTVGSFYCLCHTGFKTNDDQTMCLDINECERDAC-GNGTCRNTIGSFNCRCNHGFILSHN 1925

Query: 999  ADCGTMDKDALQCLPDC-SGHGTFDVDTQTCSCHAKW----SGEDC-SKEVCSLE---CG 1049
             DC  +D+ A      C +G     V +  C C+  +     G  C     C LE   C 
Sbjct: 1926 NDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCA 1985

Query: 1050 PHGRCV----GESCSCAAGWS--GEFC-SVRLC--DARCAEHGQCKN--GT--CLCVSGW 1096
            P G C        C C  G+S   E C  +  C  +      G C N  G+  CLC  G+
Sbjct: 1986 P-GTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGF 2044

Query: 1097 ----NGRHC---TLEGCPRSCAGHGQC---RVDNDGRWECKCF---DGWDGPD--CTTLK 1141
                +GR C    +  C     G G+C   +  N  + EC C    +GW  P   C T  
Sbjct: 2045 SLSSSGRRCQDLRMSYCYAKFEG-GKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEP 2103

Query: 1142 E----QICDDSR------DNDKDGLVDCEDPECCQSPAC 1170
            +    QIC          D+    + +C++P+ C+   C
Sbjct: 2104 DEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQC 2142



 Score = 50.8 bits (116), Expect = 7e-05
 Identities = 85/319 (26%), Positives = 132/319 (41%), Gaps = 68/319 (21%)

Query: 878  CPNG---CSGKGEC--LMG--HCQCQPGFGG--------DDCSKSVCPVLCSQRGEYING 922
            C NG   CS   +C   MG   C C+ G+ G        D+CS+++   LC   G+ +N 
Sbjct: 1367 CSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENL--NLCG-NGQCLNA 1423

Query: 923  ----ECQCNPGW----KGKECSLRHDECEVPDCNGHGHCVN----GKCSCVRGYK----G 966
                 C+C+ G+     GK C    DEC +P+    G C N     +C C  GY+    G
Sbjct: 1424 PGGYRCECDMGFVPSADGKACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSG 1482

Query: 967  KFCGEI-DCPHPTCSGHGFCIEGTCVCKKGWKGADCG---TMDKDALQCLPDCSGHGTFD 1022
              C ++ +C  PT      CI G CV   G    DC     ++   + C+   SG+   D
Sbjct: 1483 GNCTDVNECLDPTT-----CISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLD 1537

Query: 1023 V----DTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCS-CAAGWSGEFCSVRLCDA 1077
            +    D    +C +   G   SK  C   C   G+  G  C  C A  + E+    LC  
Sbjct: 1538 IRPRGDNGDTAC-SNEIGVGVSKASC---CCSLGKAWGTPCEMCPAVNTSEY--KILCPG 1591

Query: 1078 RCAEHGQCKNGTCLCVSGWNGRHCTLEGCPRSCAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
                 G+      + V   +   C  +  P  C G G+C ++  G ++C+C  G+   + 
Sbjct: 1592 -----GEGFRPNPITVILEDIDEC--QELPGLCQG-GKC-INTFGSFQCRCPTGYYLNED 1642

Query: 1138 TTLKEQICDDSRDNDKDGL 1156
            T    ++CDD  + +  G+
Sbjct: 1643 T----RVCDDVNECETPGI 1657



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 92/338 (27%), Positives = 131/338 (38%), Gaps = 61/338 (18%)

Query: 876  HNCPNGCSGKGEC--LMG--HCQCQPGF---GGDDC-SKSVCPV----LCSQRGEYING- 922
            + C     G G C   +G  +C+C  GF     +DC     C      LC + G+ IN  
Sbjct: 1893 NECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLC-RNGQCINTV 1951

Query: 923  ---ECQCNPGWK----GKECSLRHDECEV-PDCNGHGHCVN----GKCSCVRGY--KGKF 968
               +CQCN G++    G+ C +  +EC + P     G C N     +C C  GY  + + 
Sbjct: 1952 GSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEK 2010

Query: 969  CGEID-C-PHPTCSGHGFC--IEGT--CVCKKGWKGADCGTMDKDALQ--CLPD-----C 1015
            C +ID C   P     G C   EG+  C+C +G+  +  G   +D     C        C
Sbjct: 2011 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKC 2070

Query: 1016 SGHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGESCSCAAGWS-GEFCSVRL 1074
            S   + +   Q C C  K  G     E+C  E     R +   C   +G   G   S   
Sbjct: 2071 SSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQI---CPYGSGIIVGPDDSAVD 2127

Query: 1075 CDARCAEHGQCKNGTCLCVSGWNGRHCTLEG--CPRSCAGHGQCRVDND-GRWECKCFDG 1131
             D  C E   CK+G C+   G     C          C    +C V N  G   CK   G
Sbjct: 2128 MD-ECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVGNPCGNGTCKNVIG 2186

Query: 1132 WDGPDCTTLKEQICDDSRDNDKDGLVDCED-PECCQSP 1168
              G +CT      C++    +   ++ CED  EC Q+P
Sbjct: 2187 --GFECT------CEEG--FEPGPMMTCEDINECAQNP 2214



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 54/205 (26%), Positives = 74/205 (36%), Gaps = 20/205 (9%)

Query: 877  NCPNGCSGKGECLMGHCQCQPGFGGDDCSKSVCPVLCSQRGEYI-NGECQCNPGWKGKEC 935
            +C   C   G C   HC CQ G+ G  C + VC   C   G  +    C C  G+ G +C
Sbjct: 118  HCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQC 177

Query: 936  --SLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEID--CPHPTCSGHGFCIEGTCV 991
                R   C     N       G+ S +   K   C  +     HP C     C      
Sbjct: 178  ERDYRTGPCFTVISN---QMCQGQLSGIVCTKTLCCATVGRAWGHP-CE---MCPAQPHP 230

Query: 992  CKKGW-KGADCGT-MDKDALQCLPD-CSGHGTFD-VDTQTCSCHAKWSGEDCSKEVCSL- 1046
            C++G+      G   D D  Q +P  C G    + V +  C C A     + S++   + 
Sbjct: 231  CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDID 290

Query: 1047 ECGP-HGRCVGESCSCAAGWSGEFC 1070
            EC    G C G  C+     S  FC
Sbjct: 291  ECSTIPGICEGGECTNTV--SSYFC 313



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 67/233 (28%), Positives = 93/233 (39%), Gaps = 51/233 (21%)

Query: 926  CNPGW---KGKECSLRHDECEVPDCNGHGHCVNGKCSCVRGYKGKFCGEIDCPHPTCSGH 982
            C  G+   KG +C    DECEV      G C NG C   RG          C  P+    
Sbjct: 896  CGKGYSRIKGTQCE-DIDECEVFP----GVCKNGLCVNTRG-------SFKCQCPS---- 939

Query: 983  GFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE 1042
            G  ++ T       +   C    +D    LP    H    +D   CS  A W  E+C  E
Sbjct: 940  GMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHR---MDACCCSVGAAWGTEEC--E 994

Query: 1043 VCSLECGPHGRCVGESCSCAAGWSGE--------FCSVRLCDA--RCAEHGQCKN--GT- 1089
             C +   P      E C    G++ +        F  +  C        HG+C+N  G+ 
Sbjct: 995  ECPMRNTPEYE---ELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSF 1051

Query: 1090 -CLCVSGW----NGRHCT-LEGC---PRSCAGHGQCRVDNDGRWECKCFDGWD 1133
             C C SG+      R+CT ++ C   P  C G GQC V+  G +ECKC +G++
Sbjct: 1052 KCRCDSGFALDSEERNCTDIDECRISPDLC-GRGQC-VNTPGDFECKCDEGYE 1102



 Score = 43.2 bits (97), Expect = 0.015
 Identities = 44/158 (27%), Positives = 64/158 (40%), Gaps = 26/158 (16%)

Query: 880  NGCSGKGECL-MGHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLR 938
            +G  GK  C  +  C+     G  +C K    V  +  G +   +C C+PGW G      
Sbjct: 1312 SGKKGKTGCTDINECE----IGAHNCGKHA--VCTNTAGSF---KCSCSPGWIGDGIKCT 1362

Query: 939  H-DECE--VPDCNGHGHCVNG----KCSCVRGYKGK--FCGEID-C-PHPTCSGHGFCIE 987
              DEC      C+ H  C N     +C C  GY G    C ++D C  +    G+G C+ 
Sbjct: 1363 DLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLN 1422

Query: 988  G----TCVCKKGWKGADCGTMDKDALQC-LPDCSGHGT 1020
                  C C  G+  +  G   +D  +C LP+    GT
Sbjct: 1423 APGGYRCECDMGFVPSADGKACEDIDECSLPNICVFGT 1460



 Score = 41.1 bits (92), Expect = 0.059
 Identities = 69/284 (24%), Positives = 110/284 (38%), Gaps = 52/284 (18%)

Query: 892  HCQCQPGFGGDDCSKSVCPVL--CSQRGEYING---------ECQCNPGWK----GKECS 936
            HC C  GF      K+ C  +  CS R   +NG         +C C PG++    G+ C 
Sbjct: 554  HCVCNAGFHVTRDGKN-CEDMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCK 612

Query: 937  LRHDECEVPDCNGHGHCVNG----KCSC----VRGYKGKFCGEIDCPHPTCSG---HGFC 985
               +ECE P    +G CVN     +C C      G  G+ C +      TC G    G C
Sbjct: 613  -DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHM-RSTCYGGYKRGQC 670

Query: 986  IEGTCVCKKGWKGADCGTMDKDALQCLPDCSGHGTFDVDTQTCSCHAKWS-GEDCSKEVC 1044
            I+         +     T       C P C    + +      S     S G D ++   
Sbjct: 671  IKPLFGAVTKSECCCASTEYAFGEPCQP-CPAQNSAEYQALCSSGPGMTSAGSDINECAL 729

Query: 1045 SLECGPHGRCVG----ESCSCAAGW----SGEFC-SVRLC--DARCAEHGQCKNG----T 1089
              +  P+G C        C C +G+    +G+ C  +  C  ++   ++GQC+N      
Sbjct: 730  DPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFV 789

Query: 1090 CLCVSGW----NGRHC-TLEGCPRSCAGHGQCRVDNDGRWECKC 1128
            C C  G+    + + C  ++ C  S   +G C+ ++ G + C+C
Sbjct: 790  CTCPKGFIYKPDLKTCEDIDECESSPCINGVCK-NSPGSFICEC 832



 Score = 40.7 bits (91), Expect = 0.078
 Identities = 71/282 (25%), Positives = 99/282 (35%), Gaps = 62/282 (21%)

Query: 886  GECLMG----HCQCQPGFGGD----------DCSKSV--CPVLCSQ-RGEYINGECQCNP 928
            GEC+      HC C+ G+  D          +C+++   C  +C    G Y   +C C  
Sbjct: 2416 GECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSY---QCSCPK 2472

Query: 929  GW----KGKECSLRHDECEVPDCNGHGHCVNG----KCSCVRGYKGKFCGEIDCPHPT-- 978
            G+     G+ C    DEC     N    CVN      C C  G+       ID    T  
Sbjct: 2473 GYILQEDGRSCK-DLDECATKQHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSD 2531

Query: 979  ---CSGHGFCIEG----TCVCKKGWKGADCGTMDKDALQCLPD--CSGHGTFD-VDTQTC 1028
               C   G C       TC C++G+     G+  +D  +C  +  C  HG  + +    C
Sbjct: 2532 INLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQ-HGCQNIIGGYRC 2590

Query: 1029 SC------HAKWS-----GEDCSKEVCSLECGPHGRCVGESCSCAAGWSGEFCSVRLCDA 1077
            SC      H +W+      E  S  +C      H       C C AG+  E  S      
Sbjct: 2591 SCPQGYLQHYQWNQCVDENECLSAHICG-GASCHNTLGSYKCMCPAGFQYEQFS-----G 2644

Query: 1078 RCAEHGQCKNGTCLCVSG-WNGRHCTLEGCPRSC--AGHGQC 1116
             C +  +C +    C  G  N     L GCP      G G C
Sbjct: 2645 GCQDINECGSAQAPCSYGSSNTEGGYLCGCPPGYFRIGQGHC 2686


>AL359813-7|CAI23222.1|  134|Homo sapiens EGF-like-domain, multiple 9
            protein.
          Length = 134

 Score = 70.5 bits (165), Expect = 8e-11
 Identities = 38/109 (34%), Positives = 48/109 (44%), Gaps = 8/109 (7%)

Query: 1036 GEDCSKEVCSLECG-PHGRCVGE-SCSCAAGWSGEFCSVRLCDARCAEHGQCKNG-TCLC 1092
            G+    + CS  C   HG C  + SC C  GW G  C   +    C +HG C     C+C
Sbjct: 21   GQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGC-QHGTCHQPWQCIC 79

Query: 1093 VSGWNGRHCTLEG--CPRS--CAGHGQCRVDNDGRWECKCFDGWDGPDC 1137
             SGW G+ C  +   C     C   GQC  D  G + C C  G+ G DC
Sbjct: 80   HSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDC 128



 Score = 60.9 bits (141), Expect = 7e-08
 Identities = 41/129 (31%), Positives = 60/129 (46%), Gaps = 18/129 (13%)

Query: 953  CVNGKCS-CVRGYKGKFCGEIDCPHPTCSGHGFCI-EGTCVCKKGWKGADCGTMDKDALQ 1010
            C++  C  C+ G  G+     DC       HG C  +G+C C  GW+G  C    +    
Sbjct: 7    CLHLVCLLCILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVR---- 62

Query: 1011 CLPDCSGHGTFDVDTQTCSCHAKWSGEDCSKE--VCSLE--CGPHGRCV----GE-SCSC 1061
             +P C  HGT     Q C CH+ W+G+ C K+  +C+ +  C   G+C+    GE  C C
Sbjct: 63   -MPGCQ-HGTCHQPWQ-CICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVC 119

Query: 1062 AAGWSGEFC 1070
              G+ G  C
Sbjct: 120  LPGFHGRDC 128



 Score = 53.2 bits (122), Expect = 1e-05
 Identities = 35/108 (32%), Positives = 47/108 (43%), Gaps = 13/108 (12%)

Query: 1011 CLPDCS-GHGTFDVDTQTCSCHAKWSGEDCSKEVCSLECGPHGRCVGE-SCSCAAGWSGE 1068
            C   C   HG    D  +C C   W G  C + V    C  HG C     C C +GW+G+
Sbjct: 29   CSSHCDLAHGCCAPDG-SCRCDPGWEGLHCERCVRMPGC-QHGTCHQPWQCICHSGWAGK 86

Query: 1069 FCSV--RLCDAR--CAEHGQCK---NGT--CLCVSGWNGRHCTLEGCP 1107
            FC     +C  +  C   GQC     G   C+C+ G++GR C  +  P
Sbjct: 87   FCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGP 134



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 877 NCPNGCSGKGECLM--GHCQCQPGFGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKE 934
           +C + C     C    G C+C PG+ G  C + V    C     +   +C C+ GW GK 
Sbjct: 28  DCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWAGKF 87

Query: 935 CSLRHDECEVPD-CNGHGHCV---NGK--CSCVRGYKGKFC 969
           C      C     C   G C+    G+  C C+ G+ G+ C
Sbjct: 88  CDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDC 128


>M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.
          Length = 1394

 Score = 69.3 bits (162), Expect = 2e-10
 Identities = 92/308 (29%), Positives = 136/308 (44%), Gaps = 66/308 (21%)

Query: 902  DDCSKSVCPVLCSQ-RGEYINGE--CQCNPGW----KGKECSLRHDECEVPDCNGHGHCV 954
            D+C++     LCSQ R E   G   C C  G+    +G  C +  DEC  PD  G GHCV
Sbjct: 590  DECTQ--VQHLCSQGRCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCV 646

Query: 955  NG----KCS-CVRGY----KGKFCGEID-CPHPTCSGHGFCIEG----TCV-CKKGWKGA 999
            N     +C  C  GY    +G+ C +ID C +P+      C+       CV C +G++G 
Sbjct: 647  NTVGAFRCEYCDSGYRMTQRGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGW 705

Query: 1000 DCGTMDKDALQCL-PDCSGHGTFD--VDTQTCSCHAKWSGEDCSKEVCSL-ECGPHGRCV 1055
            +   +D D  +CL P+   +G       +  CSCH  ++     K    + EC     CV
Sbjct: 706  NGQCLDVD--ECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCV 763

Query: 1056 -GE--------SCSCAAGW----SGEFC-SVRLCDAR--CAEHGQCKN--GT--CLCVSG 1095
             G+         C+C  G+    + + C  +  C  R  CA HGQC+N  G+  C+C  G
Sbjct: 764  NGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCA-HGQCRNTEGSFQCVCDQG 822

Query: 1096 WN----GRHC-TLEGC--PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
            +     G HC  +  C   +S    G C ++  G ++C C DG+   D  T     C D 
Sbjct: 823  YRASGLGDHCEDINECLEDKSVCQRGDC-INTAGSYDCTCPDGFQLDDNKT-----CQDI 876

Query: 1149 RDNDKDGL 1156
             + +  GL
Sbjct: 877  NECEHPGL 884



 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 74/279 (26%), Positives = 116/279 (41%), Gaps = 58/279 (20%)

Query: 940  DECEV-PDCNGHGHCVN----GKCSCVRGYK----GKFCGEID-C---PHPTCSGHGFCI 986
            +EC V PD  G GHC+N      C C  GY+     + C +ID C    H    G     
Sbjct: 548  NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 607

Query: 987  EGT--CVCKKGWKGADCGTMDKDALQCL-PDCSGHGTFDVDTQTCSCHAKWSG------- 1036
            EG+  C+C  G+  ++ GT   D  +CL PD  G G          C    SG       
Sbjct: 608  EGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG 667

Query: 1037 --EDCSKEVCSLECGPHGRCVGE--SCSCA------AGWSGEFCSVRLC-DARCAEHGQC 1085
              ED  + +    C P  +CV    S  C        GW+G+   V  C +     +G C
Sbjct: 668  RCEDIDECLNPSTC-PDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDC 726

Query: 1086 KN--GT--CLCVSGW----NGRHC-TLEGCPR-SCAGHGQCRVDNDGRWECKCFDGWDGP 1135
             N  G+  C C  G+    + +HC  ++ C + +   +GQC+ + +G + C C  G+   
Sbjct: 727  SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK-NTEGSFRCTCGQGY--- 782

Query: 1136 DCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQ 1174
              +  K+Q C+D        + +C+    C    C++++
Sbjct: 783  QLSAAKDQ-CED--------IDECQHRHLCAHGQCRNTE 812



 Score = 37.5 bits (83), Expect = 0.73
 Identities = 41/143 (28%), Positives = 54/143 (37%), Gaps = 16/143 (11%)

Query: 899  FGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKC 958
            +G + C K  CP   S  G   N   +C PG+K    +   D   + +C   G C NG+C
Sbjct: 263  WGFNKCQK--CPKKPSYHG--YNQMMECLPGYKRVNNTFCQD---INECQLQGVCPNGEC 315

Query: 959  SCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGH 1018
                G     C     P PT S    C+    V  +  KG  C  +     QC+   S H
Sbjct: 316  LNTMGSYRCTCKIGFGPDPTFSS---CVPDPPVISEE-KG-PCYRLVSSGRQCMYPLSVH 370

Query: 1019 GTFDVDTQTCSCHAKWSGEDCSK 1041
             T     Q C C    +G  C K
Sbjct: 371  LT----KQLCCCSVGKAGPHCEK 389


>BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth
            factor beta binding protein 1 protein.
          Length = 1395

 Score = 69.3 bits (162), Expect = 2e-10
 Identities = 92/308 (29%), Positives = 136/308 (44%), Gaps = 66/308 (21%)

Query: 902  DDCSKSVCPVLCSQ-RGEYINGE--CQCNPGW----KGKECSLRHDECEVPDCNGHGHCV 954
            D+C++     LCSQ R E   G   C C  G+    +G  C +  DEC  PD  G GHCV
Sbjct: 591  DECTQ--VQHLCSQGRCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCV 647

Query: 955  NG----KCS-CVRGY----KGKFCGEID-CPHPTCSGHGFCIEG----TCV-CKKGWKGA 999
            N     +C  C  GY    +G+ C +ID C +P+      C+       CV C +G++G 
Sbjct: 648  NTVGAFRCEYCDSGYRMTQRGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGW 706

Query: 1000 DCGTMDKDALQCL-PDCSGHGTFD--VDTQTCSCHAKWSGEDCSKEVCSL-ECGPHGRCV 1055
            +   +D D  +CL P+   +G       +  CSCH  ++     K    + EC     CV
Sbjct: 707  NGQCLDVD--ECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCV 764

Query: 1056 -GE--------SCSCAAGW----SGEFC-SVRLCDAR--CAEHGQCKN--GT--CLCVSG 1095
             G+         C+C  G+    + + C  +  C  R  CA HGQC+N  G+  C+C  G
Sbjct: 765  NGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCA-HGQCRNTEGSFQCVCDQG 823

Query: 1096 WN----GRHC-TLEGC--PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
            +     G HC  +  C   +S    G C ++  G ++C C DG+   D  T     C D 
Sbjct: 824  YRASGLGDHCEDINECLEDKSVCQRGDC-INTAGSYDCTCPDGFQLDDNKT-----CQDI 877

Query: 1149 RDNDKDGL 1156
             + +  GL
Sbjct: 878  NECEHPGL 885



 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 74/279 (26%), Positives = 116/279 (41%), Gaps = 58/279 (20%)

Query: 940  DECEV-PDCNGHGHCVN----GKCSCVRGYK----GKFCGEID-C---PHPTCSGHGFCI 986
            +EC V PD  G GHC+N      C C  GY+     + C +ID C    H    G     
Sbjct: 549  NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 608

Query: 987  EGT--CVCKKGWKGADCGTMDKDALQCL-PDCSGHGTFDVDTQTCSCHAKWSG------- 1036
            EG+  C+C  G+  ++ GT   D  +CL PD  G G          C    SG       
Sbjct: 609  EGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG 668

Query: 1037 --EDCSKEVCSLECGPHGRCVGE--SCSCA------AGWSGEFCSVRLC-DARCAEHGQC 1085
              ED  + +    C P  +CV    S  C        GW+G+   V  C +     +G C
Sbjct: 669  RCEDIDECLNPSTC-PDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDC 727

Query: 1086 KN--GT--CLCVSGW----NGRHC-TLEGCPR-SCAGHGQCRVDNDGRWECKCFDGWDGP 1135
             N  G+  C C  G+    + +HC  ++ C + +   +GQC+ + +G + C C  G+   
Sbjct: 728  SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK-NTEGSFRCTCGQGY--- 783

Query: 1136 DCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQ 1174
              +  K+Q C+D        + +C+    C    C++++
Sbjct: 784  QLSAAKDQ-CED--------IDECQHRHLCAHGQCRNTE 813



 Score = 34.7 bits (76), Expect = 5.1
 Identities = 42/144 (29%), Positives = 54/144 (37%), Gaps = 17/144 (11%)

Query: 899  FGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKC 958
            +G + C K  CP   S  G   N   +C PG+K    +   D   + +C   G C NG+C
Sbjct: 263  WGFNKCQK--CPKKPSYHG--YNQMMECLPGYKRVNNTFCQD---INECQLQGVCPNGEC 315

Query: 959  SCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGH 1018
                G     C     P PT S    C+    V  +  KG  C  +     QC+   S H
Sbjct: 316  LNTMGSYRCTCKIGFGPDPTFSS---CVPDPPVISEE-KG-PCYRLVSSGRQCMHPLSVH 370

Query: 1019 GTFDVDTQTCSCH-AKWSGEDCSK 1041
             T     Q C C   K  G  C K
Sbjct: 371  LT----KQLCCCSVGKAWGPHCEK 390


>AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth
            factor-beta binding protein-1S protein.
          Length = 1394

 Score = 69.3 bits (162), Expect = 2e-10
 Identities = 92/308 (29%), Positives = 136/308 (44%), Gaps = 66/308 (21%)

Query: 902  DDCSKSVCPVLCSQ-RGEYINGE--CQCNPGW----KGKECSLRHDECEVPDCNGHGHCV 954
            D+C++     LCSQ R E   G   C C  G+    +G  C +  DEC  PD  G GHCV
Sbjct: 590  DECTQ--VQHLCSQGRCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEGHCV 646

Query: 955  NG----KCS-CVRGY----KGKFCGEID-CPHPTCSGHGFCIEG----TCV-CKKGWKGA 999
            N     +C  C  GY    +G+ C +ID C +P+      C+       CV C +G++G 
Sbjct: 647  NTVGAFRCEYCDSGYRMTQRGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGW 705

Query: 1000 DCGTMDKDALQCL-PDCSGHGTFD--VDTQTCSCHAKWSGEDCSKEVCSL-ECGPHGRCV 1055
            +   +D D  +CL P+   +G       +  CSCH  ++     K    + EC     CV
Sbjct: 706  NGQCLDVD--ECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCV 763

Query: 1056 -GE--------SCSCAAGW----SGEFC-SVRLCDAR--CAEHGQCKN--GT--CLCVSG 1095
             G+         C+C  G+    + + C  +  C  R  CA HGQC+N  G+  C+C  G
Sbjct: 764  NGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCA-HGQCRNTEGSFQCVCDQG 822

Query: 1096 WN----GRHC-TLEGC--PRSCAGHGQCRVDNDGRWECKCFDGWDGPDCTTLKEQICDDS 1148
            +     G HC  +  C   +S    G C ++  G ++C C DG+   D  T     C D 
Sbjct: 823  YRASGLGDHCEDINECLEDKSVCQRGDC-INTAGSYDCTCPDGFQLDDNKT-----CQDI 876

Query: 1149 RDNDKDGL 1156
             + +  GL
Sbjct: 877  NECEHPGL 884



 Score = 56.8 bits (131), Expect = 1e-06
 Identities = 74/279 (26%), Positives = 116/279 (41%), Gaps = 58/279 (20%)

Query: 940  DECEV-PDCNGHGHCVN----GKCSCVRGYK----GKFCGEID-C---PHPTCSGHGFCI 986
            +EC V PD  G GHC+N      C C  GY+     + C +ID C    H    G     
Sbjct: 548  NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENT 607

Query: 987  EGT--CVCKKGWKGADCGTMDKDALQCL-PDCSGHGTFDVDTQTCSCHAKWSG------- 1036
            EG+  C+C  G+  ++ GT   D  +CL PD  G G          C    SG       
Sbjct: 608  EGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRG 667

Query: 1037 --EDCSKEVCSLECGPHGRCVGE--SCSCA------AGWSGEFCSVRLC-DARCAEHGQC 1085
              ED  + +    C P  +CV    S  C        GW+G+   V  C +     +G C
Sbjct: 668  RCEDIDECLNPSTC-PDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDC 726

Query: 1086 KN--GT--CLCVSGW----NGRHC-TLEGCPR-SCAGHGQCRVDNDGRWECKCFDGWDGP 1135
             N  G+  C C  G+    + +HC  ++ C + +   +GQC+ + +G + C C  G+   
Sbjct: 727  SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK-NTEGSFRCTCGQGY--- 782

Query: 1136 DCTTLKEQICDDSRDNDKDGLVDCEDPECCQSPACKSSQ 1174
              +  K+Q C+D        + +C+    C    C++++
Sbjct: 783  QLSAAKDQ-CED--------IDECQHRHLCAHGQCRNTE 812



 Score = 37.9 bits (84), Expect = 0.55
 Identities = 41/143 (28%), Positives = 54/143 (37%), Gaps = 16/143 (11%)

Query: 899  FGGDDCSKSVCPVLCSQRGEYINGECQCNPGWKGKECSLRHDECEVPDCNGHGHCVNGKC 958
            +G + C K  CP   S  G   N   +C PG+K    +   D   + +C   G C NG+C
Sbjct: 263  WGFNKCQK--CPKKPSYHG--YNQMMECLPGYKRVNNTFCQD---INECQLQGVCPNGEC 315

Query: 959  SCVRGYKGKFCGEIDCPHPTCSGHGFCIEGTCVCKKGWKGADCGTMDKDALQCLPDCSGH 1018
                G     C     P PT S    C+    V  +  KG  C  +     QC+   S H
Sbjct: 316  LNTMGSYRCTCKIGFGPDPTFSS---CVPDPPVISEE-KG-PCYRLVSSGRQCMHPLSVH 370

Query: 1019 GTFDVDTQTCSCHAKWSGEDCSK 1041
             T     Q C C    +G  C K
Sbjct: 371  LT----KQLCCCSVGKAGPHCEK 389


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.318    0.135    0.414 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 436,095,952
Number of Sequences: 224733
Number of extensions: 19706415
Number of successful extensions: 59558
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 357
Number of HSP's successfully gapped in prelim test: 628
Number of HSP's that attempted gapping in prelim test: 38106
Number of HSP's gapped (non-prelim): 8112
length of query: 2969
length of database: 73,234,838
effective HSP length: 103
effective length of query: 2866
effective length of database: 50,087,339
effective search space: 143550313574
effective search space used: 143550313574
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 74 (33.9 bits)