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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001093-TA|BGIBMGA001093-PA|IPR003698|Lipoate synthase,
IPR007197|Radical SAM, IPR006638|Elongator protein 3/MiaB/NifB
         (366 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC023635-1|AAH23635.1|  372|Homo sapiens lipoic acid synthetase ...   465   e-130
AJ224162-1|CAA11859.1|  113|Homo sapiens lipoic acid synthetase ...   152   2e-36
BC062751-1|AAH62751.1|  142|Homo sapiens Unknown (protein for MG...   136   9e-32

>BC023635-1|AAH23635.1|  372|Homo sapiens lipoic acid synthetase
           protein.
          Length = 372

 Score =  465 bits (1146), Expect = e-130
 Identities = 216/338 (63%), Positives = 260/338 (76%), Gaps = 4/338 (1%)

Query: 27  DAIREKLKEGPNLTDFISEDRP--KNWDEYQGKLKREKGESERLRLPPWLKTTIPTGSKF 84
           D  +E L+ GP+L DF+S D      WDEY+G LKR+KGE  RLRLPPWLKT IP G  +
Sbjct: 33  DKKKELLQNGPDLQDFVSGDLADRSTWDEYKGNLKRQKGE--RLRLPPWLKTEIPMGKNY 90

Query: 85  NEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRGCMFCSVKTSR 144
           N++K  LR+L L TVCEEARCPNIGECW GG++  +TATIMLMGDTCTRGC FCSVKT+R
Sbjct: 91  NKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTAR 150

Query: 145 NPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAETVKEIKKLNKDILVE 204
           NPPPLD  EP NTA AI  WG+ Y+VLTSVDRDD+PDGG+ H A+TV  +K+ N  ILVE
Sbjct: 151 NPPPLDASEPYNTAKAIAEWGLDYVVLTSVDRDDMPDGGAEHIAKTVSYLKERNPKILVE 210

Query: 205 CLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINP 264
           CL PDFR     + +VA SGLDV+AHNVETV  L   VRDPR  + Q+L+VL+ AK++ P
Sbjct: 211 CLTPDFRGDLKAIEKVALSGLDVYAHNVETVPELQSKVRDPRVNFDQSLRVLKHAKKVQP 270

Query: 265 DLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPARFQQ 324
           D+I+K+SIMLGLGE D QV  TMK LREA VDC+TLGQYMQPT++HLKV EY+TP +F+ 
Sbjct: 271 DVISKTSIMLGLGENDEQVYATMKALREADVDCLTLGQYMQPTRRHLKVEEYITPEKFKY 330

Query: 325 WEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRDRK 362
           WE  G +LGF Y ASG LVRSSY+AGEFF+  ++  RK
Sbjct: 331 WEKVGNELGFHYTASGPLVRSSYKAGEFFLKNLVAKRK 368


>AJ224162-1|CAA11859.1|  113|Homo sapiens lipoic acid synthetase
           protein.
          Length = 113

 Score =  152 bits (369), Expect = 2e-36
 Identities = 70/108 (64%), Positives = 87/108 (80%)

Query: 255 VLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVF 314
           VL+ AK++ PD+I+K+SIMLGLGE D QV  TMK LREA VDC+TLGQYMQPT++HLKV 
Sbjct: 2   VLKHAKKVQPDVISKTSIMLGLGENDEQVYATMKALREADVDCLTLGQYMQPTRRHLKVE 61

Query: 315 EYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRDRK 362
           EY+TP +F+ WE  G +LGF Y ASG LVRSSY+AGEFF+  ++  RK
Sbjct: 62  EYITPEKFKYWEKVGNELGFHYTASGPLVRSSYKAGEFFLKNLVAKRK 109


>BC062751-1|AAH62751.1|  142|Homo sapiens Unknown (protein for
           MGC:72117) protein.
          Length = 142

 Score =  136 bits (330), Expect = 9e-32
 Identities = 62/102 (60%), Positives = 76/102 (74%), Gaps = 4/102 (3%)

Query: 27  DAIREKLKEGPNLTDFISEDRP--KNWDEYQGKLKREKGESERLRLPPWLKTTIPTGSKF 84
           D  +E L+ GP+L DF+S D      WDEY+G LKR+KGE  RLRLPPWLKT IP G  +
Sbjct: 33  DKKKELLQNGPDLQDFVSGDLADRSTWDEYKGNLKRQKGE--RLRLPPWLKTEIPMGKNY 90

Query: 85  NEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIML 126
           N++K  LR+L L TVCEEARCPNIGECW GG++  +TATIM+
Sbjct: 91  NKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYATATATIMV 132


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.319    0.135    0.408 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 54,065,428
Number of Sequences: 224733
Number of extensions: 2260784
Number of successful extensions: 9341
Number of sequences better than 10.0: 3
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 9334
Number of HSP's gapped (non-prelim): 3
length of query: 366
length of database: 73,234,838
effective HSP length: 91
effective length of query: 275
effective length of database: 52,784,135
effective search space: 14515637125
effective search space used: 14515637125
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 66 (30.7 bits)

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