Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001093-TA|BGIBMGA001093-PA|IPR003698|Lipoate synthase,
IPR007197|Radical SAM, IPR006638|Elongator protein 3/MiaB/NifB
(366 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B4F49 Cluster: PREDICTED: similar to lipoic aci... 483 e-135
UniRef50_O43766 Cluster: Lipoic acid synthetase, mitochondrial p... 465 e-130
UniRef50_A5E450 Cluster: Lipoic acid synthetase, mitochondrial; ... 405 e-112
UniRef50_Q8LSZ8 Cluster: Lipoic acid synthase; n=7; cellular org... 402 e-111
UniRef50_A6QV10 Cluster: Lipoic acid synthetase, mitochondrial; ... 400 e-110
UniRef50_P32875 Cluster: Lipoic acid synthetase, mitochondrial p... 393 e-108
UniRef50_Q7RBD6 Cluster: Lipoic acid synthetase, putative; n=8; ... 365 e-100
UniRef50_Q4QDI6 Cluster: Lipoic acid synthetase, mitochondrial, ... 353 4e-96
UniRef50_Q9RWA4 Cluster: Lipoyl synthase; n=33; cellular organis... 317 3e-85
UniRef50_Q9Y9E3 Cluster: Probable lipoyl synthase; n=4; cellular... 287 2e-76
UniRef50_Q0W150 Cluster: Putative lipoate synthetase; n=1; uncul... 280 5e-74
UniRef50_Q4UK97 Cluster: Lipoyl synthase; n=131; Bacteria|Rep: L... 278 1e-73
UniRef50_Q8R9E1 Cluster: Lipoyl synthase; n=31; cellular organis... 275 1e-72
UniRef50_Q4JBV4 Cluster: Probable lipoyl synthase; n=4; cellular... 270 3e-71
UniRef50_Q028Q9 Cluster: Lipoic acid synthetase precursor; n=2; ... 268 2e-70
UniRef50_Q8ERL8 Cluster: Lipoyl synthase; n=51; Bacteria|Rep: Li... 267 4e-70
UniRef50_Q8YWC1 Cluster: Lipoyl synthase 1; n=18; Cyanobacteria|... 264 3e-69
UniRef50_A1HSS2 Cluster: Lipoic acid synthetase; n=2; Bacteria|R... 262 8e-69
UniRef50_A6DU97 Cluster: Lipoyl synthase; n=1; Lentisphaera aran... 262 1e-68
UniRef50_Q7VKB1 Cluster: Lipoyl synthase; n=9; cellular organism... 262 1e-68
UniRef50_Q9PDW0 Cluster: Lipoyl synthase; n=257; Bacteria|Rep: L... 260 5e-68
UniRef50_Q8DL83 Cluster: Lipoyl synthase 2; n=7; Bacteria|Rep: L... 252 1e-65
UniRef50_A5MZI9 Cluster: LipA2; n=1; Clostridium kluyveri DSM 55... 251 2e-65
UniRef50_Q8ZUR9 Cluster: Probable lipoyl synthase; n=4; cellular... 251 2e-65
UniRef50_Q0LDD9 Cluster: Lipoic acid synthetase; n=1; Herpetosip... 249 8e-65
UniRef50_P61199 Cluster: Lipoyl synthase; n=4; Bacteria|Rep: Lip... 244 2e-63
UniRef50_Q3ARP5 Cluster: Lipoate synthase; n=11; Bacteria|Rep: L... 243 7e-63
UniRef50_Q8F3V7 Cluster: Lipoyl synthase; n=4; Leptospira|Rep: L... 239 6e-62
UniRef50_O67368 Cluster: Lipoyl synthase; n=1; Aquifex aeolicus|... 237 2e-61
UniRef50_A6GIK5 Cluster: Lipoyl synthase; n=2; Bacteria|Rep: Lip... 237 4e-61
UniRef50_Q821K6 Cluster: Lipoyl synthase; n=4; Chlamydiaceae|Rep... 235 1e-60
UniRef50_Q9PJI2 Cluster: Lipoyl synthase; n=4; Chlamydiales|Rep:... 231 2e-59
UniRef50_Q7VBJ3 Cluster: Lipoyl synthase 2; n=37; Cyanobacteria|... 224 3e-57
UniRef50_Q7UH37 Cluster: Lipoyl synthase; n=3; Planctomycetaceae... 222 1e-56
UniRef50_P61194 Cluster: Lipoyl synthase; n=54; Bacteria|Rep: Li... 217 3e-55
UniRef50_P61196 Cluster: Lipoyl synthase; n=7; Bacteria|Rep: Lip... 212 1e-53
UniRef50_A6Q3H7 Cluster: Lipoate synthase; n=1; Nitratiruptor sp... 192 2e-47
UniRef50_Q01AS9 Cluster: Lipoic acid synthase; n=1; Ostreococcus... 163 9e-39
UniRef50_Q6P5Q6 Cluster: LIAS protein; n=5; Catarrhini|Rep: LIAS... 136 6e-31
UniRef50_A7R5C7 Cluster: Chromosome undetermined scaffold_937, w... 121 3e-26
UniRef50_Q5BXH1 Cluster: SJCHGC04147 protein; n=1; Schistosoma j... 116 7e-25
UniRef50_Q3ERB0 Cluster: Lipoic acid synthetase; n=1; Bacillus t... 50 1e-04
UniRef50_A3EVI4 Cluster: Biotin synthase; n=1; Leptospirillum sp... 44 0.008
UniRef50_A7HG97 Cluster: Biotin synthase; n=2; Anaeromyxobacter|... 41 0.044
UniRef50_Q8EAH7 Cluster: Biotin synthase family protein; n=3; Sh... 41 0.059
UniRef50_Q72L21 Cluster: Biotin synthase; n=2; Thermus thermophi... 40 0.077
UniRef50_Q4AJU3 Cluster: Integrase, catalytic region; n=3; Chlor... 40 0.077
UniRef50_Q04PJ5 Cluster: 2-methylthioadenine synthetase; n=4; Le... 40 0.14
UniRef50_Q97MI6 Cluster: Biotine synthase; n=4; Clostridiales|Re... 39 0.18
UniRef50_Q9FCC3 Cluster: Biotin synthase; n=9; Actinomycetales|R... 37 0.72
UniRef50_Q896R1 Cluster: Pyruvate formate-lyase; n=5; Clostridiu... 37 0.72
UniRef50_A7CVG2 Cluster: RNA modification enzyme, MiaB family pr... 37 0.72
UniRef50_A6DP84 Cluster: Biotin synthase; n=1; Lentisphaera aran... 37 0.72
UniRef50_A0LJA8 Cluster: Biotin synthase; n=1; Syntrophobacter f... 37 0.72
UniRef50_Q1PUX5 Cluster: Similar to biotin synthase; n=1; Candid... 37 0.95
UniRef50_A1ID94 Cluster: Biotin synthase; n=1; Candidatus Desulf... 37 0.95
UniRef50_A1VB97 Cluster: Biotin synthase; n=4; Deltaproteobacter... 36 1.3
UniRef50_O26568 Cluster: Sensory transduction histidine kinase; ... 35 2.9
UniRef50_P73127 Cluster: UPF0004 protein sll0996; n=37; Cyanobac... 35 2.9
UniRef50_A3TFV2 Cluster: Putative uncharacterized protein; n=1; ... 35 3.8
UniRef50_A5K8V8 Cluster: Kinesin motor domain containing protein... 35 3.8
UniRef50_UPI0000E488B2 Cluster: PREDICTED: similar to cell-cycle... 34 5.1
UniRef50_Q2LY09 Cluster: Biotin synthase; n=1; Syntrophus acidit... 34 5.1
UniRef50_Q1NNS2 Cluster: Biotin synthase; n=3; delta proteobacte... 34 5.1
UniRef50_Q1IV15 Cluster: Response regulator receiver protein; n=... 34 5.1
UniRef50_A1KQR7 Cluster: RhiB protein; n=1; Burkholderia rhizoxi... 34 5.1
UniRef50_A2SS95 Cluster: Radical SAM domain protein; n=1; Methan... 34 6.7
UniRef50_Q47VK0 Cluster: Chaperone surA precursor; n=2; Alteromo... 34 6.7
UniRef50_Q74CT7 Cluster: Biotin synthetase; n=7; Desulfuromonada... 33 8.9
UniRef50_A6SXU1 Cluster: MiaB-like tRNA modifying enzyme; n=19; ... 33 8.9
UniRef50_A4M7N1 Cluster: MiaB-like tRNA modifying enzyme YliG; n... 33 8.9
UniRef50_Q5C3Q8 Cluster: SJCHGC02377 protein; n=2; Schistosoma j... 33 8.9
>UniRef50_UPI00015B4F49 Cluster: PREDICTED: similar to lipoic acid
synthetase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to lipoic acid synthetase - Nasonia vitripennis
Length = 648
Score = 483 bits (1192), Expect = e-135
Identities = 224/332 (67%), Positives = 266/332 (80%), Gaps = 3/332 (0%)
Query: 31 EKLKEGPNLTDFISEDRPKNWDEYQGKLKREKGESERLRLPPWLKTTIPTGSKFNEIKQQ 90
+KL+ GP L +FIS D EY G LK KG+ RLRLPPWLKT IP G ++ IK Q
Sbjct: 311 QKLENGPQLENFISGDATAT--EYDGILKLAKGDKSRLRLPPWLKTQIPMGKNYSRIKSQ 368
Query: 91 LRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRGCMFCSVKTSRNPPPLD 150
LR L+LSTVCEEARCPNIGECW GG HG +TATIMLMGDTCTRGC FCSVKT+R PPPLD
Sbjct: 369 LRDLRLSTVCEEARCPNIGECWGGGAHGTATATIMLMGDTCTRGCRFCSVKTARAPPPLD 428
Query: 151 PEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAETVKEIKKLNKDILVECLVPDF 210
PEEP+NTA AI WG+ Y+VLTSVDRDD+ DGG+ H A TV+E+K +ILVECLVPDF
Sbjct: 429 PEEPKNTATAITEWGLDYVVLTSVDRDDVADGGASHIAATVRELKN-RSNILVECLVPDF 487
Query: 211 RAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKS 270
+ V V SGLDV+AHN+ETVERLTPFVRD RA Y+Q+L +L AK++NPDLITKS
Sbjct: 488 QGNLDSVKTVVESGLDVYAHNIETVERLTPFVRDRRARYKQSLSMLGGAKKVNPDLITKS 547
Query: 271 SIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPARFQQWEARGR 330
SIMLGLGETD +V QTMKDLR AGV+ +TLGQYMQPTK+HLKV EYVTP +F+ WE G+
Sbjct: 548 SIMLGLGETDDEVMQTMKDLRAAGVEALTLGQYMQPTKRHLKVIEYVTPEKFKYWEKVGQ 607
Query: 331 QLGFLYVASGALVRSSYRAGEFFISAVLRDRK 362
+LGFLY ASG LVRSSY+AGE+F++ +L++++
Sbjct: 608 ELGFLYTASGPLVRSSYKAGEYFLTNILKEKR 639
>UniRef50_O43766 Cluster: Lipoic acid synthetase, mitochondrial
precursor; n=41; cellular organisms|Rep: Lipoic acid
synthetase, mitochondrial precursor - Homo sapiens
(Human)
Length = 372
Score = 465 bits (1146), Expect = e-130
Identities = 216/338 (63%), Positives = 260/338 (76%), Gaps = 4/338 (1%)
Query: 27 DAIREKLKEGPNLTDFISEDRP--KNWDEYQGKLKREKGESERLRLPPWLKTTIPTGSKF 84
D +E L+ GP+L DF+S D WDEY+G LKR+KGE RLRLPPWLKT IP G +
Sbjct: 33 DKKKELLQNGPDLQDFVSGDLADRSTWDEYKGNLKRQKGE--RLRLPPWLKTEIPMGKNY 90
Query: 85 NEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRGCMFCSVKTSR 144
N++K LR+L L TVCEEARCPNIGECW GG++ +TATIMLMGDTCTRGC FCSVKT+R
Sbjct: 91 NKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCRFCSVKTAR 150
Query: 145 NPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAETVKEIKKLNKDILVE 204
NPPPLD EP NTA AI WG+ Y+VLTSVDRDD+PDGG+ H A+TV +K+ N ILVE
Sbjct: 151 NPPPLDASEPYNTAKAIAEWGLDYVVLTSVDRDDMPDGGAEHIAKTVSYLKERNPKILVE 210
Query: 205 CLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINP 264
CL PDFR + +VA SGLDV+AHNVETV L VRDPR + Q+L+VL+ AK++ P
Sbjct: 211 CLTPDFRGDLKAIEKVALSGLDVYAHNVETVPELQSKVRDPRVNFDQSLRVLKHAKKVQP 270
Query: 265 DLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPARFQQ 324
D+I+K+SIMLGLGE D QV TMK LREA VDC+TLGQYMQPT++HLKV EY+TP +F+
Sbjct: 271 DVISKTSIMLGLGENDEQVYATMKALREADVDCLTLGQYMQPTRRHLKVEEYITPEKFKY 330
Query: 325 WEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRDRK 362
WE G +LGF Y ASG LVRSSY+AGEFF+ ++ RK
Sbjct: 331 WEKVGNELGFHYTASGPLVRSSYKAGEFFLKNLVAKRK 368
>UniRef50_A5E450 Cluster: Lipoic acid synthetase, mitochondrial;
n=4; Fungi/Metazoa group|Rep: Lipoic acid synthetase,
mitochondrial - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 432
Score = 405 bits (998), Expect = e-112
Identities = 199/334 (59%), Positives = 243/334 (72%), Gaps = 5/334 (1%)
Query: 31 EKLKEGPNLTDFISEDRPKNWDEYQGKLKREKGESERLRLPPWLKTTIPTGSKFNEIKQQ 90
++L +GP+ DF+S + K+ E +L R+ + +LP WLK IP G F+ +K
Sbjct: 85 DELNKGPSFDDFVS-GKAKDMLEDPLELARKDPNA---KLPLWLKVPIPKGKSFHNVKND 140
Query: 91 LRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRGCMFCSVKTSRNPPPLD 150
+R LKLSTVCEEA+CPNIGECW GGK +TATIML+GDTCTRGC FCSVKT+R P D
Sbjct: 141 VRELKLSTVCEEAKCPNIGECW-GGKKSEATATIMLLGDTCTRGCRFCSVKTNRKPGKPD 199
Query: 151 PEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAETVKEIKKLNKDILVECLVPDF 210
P EP NTA AI+ WG+GY+VLT+VDRDDL DGG+ H ETV++IK ILVE L DF
Sbjct: 200 PMEPENTAEAISRWGLGYVVLTTVDRDDLIDGGANHLKETVQKIKFKAPQILVEVLGGDF 259
Query: 211 RAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKS 270
R V +A+SGLDV+AHN+ETVE LTP +RD RA YRQ+L VL+ AKE P LITK+
Sbjct: 260 RGDLEMVKILANSGLDVYAHNMETVEALTPHIRDRRATYRQSLAVLRTAKETKPSLITKT 319
Query: 271 SIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPARFQQWEARGR 330
S+MLG GETD Q+ QT+KDLRE G D VT GQYM+PTK+H+KV EYVTP +F W
Sbjct: 320 SLMLGFGETDDQIRQTLKDLREVGCDVVTFGQYMRPTKRHMKVVEYVTPEKFDYWRDVAL 379
Query: 331 QLGFLYVASGALVRSSYRAGEFFISAVLRDRKVN 364
++GFLYVASG LVRSSY+AGE FI VL+ RK N
Sbjct: 380 EMGFLYVASGPLVRSSYKAGEAFIENVLKKRKHN 413
>UniRef50_Q8LSZ8 Cluster: Lipoic acid synthase; n=7; cellular
organisms|Rep: Lipoic acid synthase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 394
Score = 402 bits (989), Expect = e-111
Identities = 188/339 (55%), Positives = 239/339 (70%), Gaps = 3/339 (0%)
Query: 25 KLDAIREKLKEGPNLTDFISEDRPKNWDEYQG---KLKREKGESERLRLPPWLKTTIPTG 81
K ++ ++++ +L + E K + Y G K+ G ++ P WL+ P G
Sbjct: 49 KAVSLSSEMEDSSSLKKSLMELEGKKSEPYPGGMPKMGPFTGRDPNVKKPAWLRQKAPQG 108
Query: 82 SKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRGCMFCSVK 141
+F E+K+ L L L+TVCEEA+CPNIGECW+GG G +TATIM++GDTCTRGC FC+VK
Sbjct: 109 ERFQEVKESLSRLNLNTVCEEAQCPNIGECWNGGGDGVATATIMVLGDTCTRGCRFCAVK 168
Query: 142 TSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAETVKEIKKLNKDI 201
TSRNPPP DP EP NTA AI WGV YIV+TSVDRDD+PDGGS HFA+TVK +K+ DI
Sbjct: 169 TSRNPPPPDPMEPENTAKAIASWGVDYIVITSVDRDDIPDGGSGHFAQTVKAMKRHKPDI 228
Query: 202 LVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKE 261
++ECL DFR V + SGLDVFAHNVETV+RL VRDPRAGY Q++ VL+ AK
Sbjct: 229 MIECLTSDFRGDLEAVDTLVHSGLDVFAHNVETVKRLQRLVRDPRAGYEQSMSVLKHAKI 288
Query: 262 INPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPAR 321
P +ITK+SIMLGLGETD ++++ M DLR VD +TLGQY+QPT HL V EYVTP +
Sbjct: 289 SKPGMITKTSIMLGLGETDEELKEAMADLRAIDVDILTLGQYLQPTPLHLTVKEYVTPEK 348
Query: 322 FQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRD 360
F W+ G +GF YVASG LVRSSYRAGE F+ ++++
Sbjct: 349 FDFWKTYGESIGFRYVASGPLVRSSYRAGELFVKTMVKE 387
>UniRef50_A6QV10 Cluster: Lipoic acid synthetase, mitochondrial;
n=1; Ajellomyces capsulatus NAm1|Rep: Lipoic acid
synthetase, mitochondrial - Ajellomyces capsulatus NAm1
Length = 465
Score = 400 bits (984), Expect = e-110
Identities = 187/299 (62%), Positives = 223/299 (74%)
Query: 64 ESERLRLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTAT 123
+ E RLPPWLKT IP S + IK LR L L TVCEEARCPNI +CW G A+TAT
Sbjct: 37 KKEITRLPPWLKTPIPDSSNYKRIKNDLRGLNLHTVCEEARCPNIADCWGGSSKSAATAT 96
Query: 124 IMLMGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGG 183
IMLMGDTCTRGC FCSVKTS PPPLDP EP NTA A++ WG+GY+VLT+VDRDDL DGG
Sbjct: 97 IMLMGDTCTRGCRFCSVKTSNKPPPLDPHEPDNTAEALSRWGLGYVVLTTVDRDDLADGG 156
Query: 184 SLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVR 243
+ H A+TV +IK+ +ILVECL D+ VA VA+SGLDVFAHNVETVE LTPFVR
Sbjct: 157 ARHCAKTVMKIKQKAPNILVECLTGDYAGDLDMVALVANSGLDVFAHNVETVEALTPFVR 216
Query: 244 DPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQY 303
D RA ++Q+L+VL+ AK P+LITK+S MLGLGET+AQ+ ++ LR VD VT GQY
Sbjct: 217 DRRASFQQSLRVLKAAKAAKPELITKTSFMLGLGETEAQLWDALRALRAINVDVVTFGQY 276
Query: 304 MQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRDRK 362
M+PTK+H+ V EYV P F W+ R ++GFLY ASG LVRSSY+AGE FI VL+ R+
Sbjct: 277 MRPTKRHMAVHEYVRPDVFDLWKERALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRR 335
>UniRef50_P32875 Cluster: Lipoic acid synthetase, mitochondrial
precursor; n=42; Eukaryota|Rep: Lipoic acid synthetase,
mitochondrial precursor - Saccharomyces cerevisiae
(Baker's yeast)
Length = 414
Score = 393 bits (968), Expect = e-108
Identities = 191/345 (55%), Positives = 240/345 (69%), Gaps = 2/345 (0%)
Query: 19 RYKHSNKLDAIREKLKEGPNLTDFISEDRPKNWDEYQGKLKREKGESERLRLPPWLKTTI 78
R + ++ ++ L GP+ DF+S K + K ++ E+++L P WLK I
Sbjct: 71 RKGNRKRITEFKDALNLGPSFADFVSGKASKMILDPLEKARQNTEEAKKL--PRWLKVPI 128
Query: 79 PTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRGCMFC 138
P G+ ++++K ++ L LSTVCEEARCPNIGECW G +TATIML+GDTCTRGC FC
Sbjct: 129 PKGTNYHKLKGDVKELGLSTVCEEARCPNIGECWGGKDKSKATATIMLLGDTCTRGCRFC 188
Query: 139 SVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAETVKEIKKLN 198
SVKT+R P DP EP NTA AI WG+GY+VLT+VDRDDL DGG+ H AETV++IK+
Sbjct: 189 SVKTNRTPSKPDPMEPENTAEAIKRWGLGYVVLTTVDRDDLVDGGANHLAETVRKIKQKA 248
Query: 199 KDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQM 258
+ LVE L DFR V +A GLDV+AHN+ETVE LTP VRD RA YRQ+L VL+
Sbjct: 249 PNTLVETLSGDFRGDLKMVDIMAQCGLDVYAHNLETVESLTPHVRDRRATYRQSLSVLER 308
Query: 259 AKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVT 318
AK P LITK+SIMLGLGETD Q+ QT+KDLR D VT GQYM+PTK+H+KV EYV
Sbjct: 309 AKATVPSLITKTSIMLGLGETDEQITQTLKDLRNIQCDVVTFGQYMRPTKRHMKVVEYVK 368
Query: 319 PARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRDRKV 363
P +F W+ R ++GFLY ASG LVRSSY+AGE FI VL+ R +
Sbjct: 369 PEKFDYWKERALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRNM 413
>UniRef50_Q7RBD6 Cluster: Lipoic acid synthetase, putative; n=8;
cellular organisms|Rep: Lipoic acid synthetase, putative
- Plasmodium yoelii yoelii
Length = 502
Score = 365 bits (899), Expect = e-100
Identities = 178/318 (55%), Positives = 223/318 (70%), Gaps = 7/318 (2%)
Query: 38 NLTDFISEDRPKNWDEYQGKLKREK-GESERLRLPPWLKTTIPTGSKFNEIKQQLRSLKL 96
N+ D + + +N DE K+K K G + + P W P G K+ ++K L LKL
Sbjct: 130 NIKDCYTNENAQN-DEKNKKVKIPKVGNAMPEKKPDWFHVPAPNGEKYKKLKSDLGKLKL 188
Query: 97 STVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRGCMFCSVKTSRNPPPLDPEEPRN 156
TVCEEA+CPNIGECW+ G TATIML+GDTCTRGC FCS+KTS PPP D EP N
Sbjct: 189 HTVCEEAQCPNIGECWNIG-----TATIMLLGDTCTRGCKFCSIKTSSKPPPPDINEPFN 243
Query: 157 TAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAETVKEIKKLNKDILVECLVPDFRAVRGC 216
TA AI W + YIV+TSVDRDDLPDGG+ HFA+TV+ IK IL+ECLV DF+
Sbjct: 244 TAKAICEWDINYIVITSVDRDDLPDGGADHFAKTVELIKFSKPSILIECLVSDFQGNIDS 303
Query: 217 VARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGL 276
+ R+A SGLDV+AHN+ETV+RL +VRD RA Y Q+L VL+ AKEINP+L TK+SIMLGL
Sbjct: 304 IKRLALSGLDVYAHNIETVKRLQKYVRDKRANYEQSLYVLKKAKEINPNLYTKTSIMLGL 363
Query: 277 GETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPARFQQWEARGRQLGFLY 336
GET +V QTMKD R +D +T GQY++PTK HL V EY++P F ++ G ++GF Y
Sbjct: 364 GETQDEVLQTMKDARSNDIDVITFGQYLRPTKNHLNVVEYISPQMFNYYKDVGLKMGFKY 423
Query: 337 VASGALVRSSYRAGEFFI 354
+ASG LVRSSY AGE+F+
Sbjct: 424 IASGPLVRSSYMAGEYFM 441
>UniRef50_Q4QDI6 Cluster: Lipoic acid synthetase, mitochondrial,
putative; n=7; Eukaryota|Rep: Lipoic acid synthetase,
mitochondrial, putative - Leishmania major
Length = 410
Score = 353 bits (868), Expect = 4e-96
Identities = 166/299 (55%), Positives = 212/299 (70%), Gaps = 6/299 (2%)
Query: 70 LPPWLKTTIPTGS----KFNEIKQQLRSLKLSTVCEEARCPNIGECWSGG-KHGASTATI 124
LPPW+K +P G +FN I++ +R LSTVCEEA+CPNIGECW G + G +TATI
Sbjct: 91 LPPWIKLKVPKGMTHRPRFNRIRRSMREKNLSTVCEEAKCPNIGECWGGSDEEGTATATI 150
Query: 125 MLMGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGS 184
M+MG CTRGC FCSV TSR PPPLDPEEP A A++ GV YIV+T VDRDDLPDGG+
Sbjct: 151 MVMGSHCTRGCRFCSVLTSRRPPPLDPEEPEKVAAAVHEMGVDYIVMTMVDRDDLPDGGA 210
Query: 185 LHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRD 244
H + IKK N ++++E LV DF V ++A + L V+AHN+E VER+TP VRD
Sbjct: 211 SHVCCCIHTIKKKNPELMLEALVGDFHGDLKLVEQLAVTPLSVYAHNIECVERITPRVRD 270
Query: 245 PRAGYRQTLKVLQ-MAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQY 303
RA YRQ+L+ L+ + K N +++TKSSIMLGLGE +A+V QT++DLR AGV VTLGQY
Sbjct: 271 RRASYRQSLQTLEHVTKWTNGNMLTKSSIMLGLGEEEAEVRQTLRDLRTAGVSAVTLGQY 330
Query: 304 MQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRDRK 362
+QP+ LKV Y P F+ WE +GFLY ASG +VRSSYRAGE++I +L+ R+
Sbjct: 331 LQPSHTRLKVSRYAHPKEFEMWEKEAMDMGFLYCASGPMVRSSYRAGEYYIKNILKQRQ 389
>UniRef50_Q9RWA4 Cluster: Lipoyl synthase; n=33; cellular
organisms|Rep: Lipoyl synthase - Deinococcus radiodurans
Length = 331
Score = 317 bits (779), Expect = 3e-85
Identities = 155/283 (54%), Positives = 191/283 (67%), Gaps = 5/283 (1%)
Query: 67 RLRLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIML 126
R + P WLK TIPTG F E+++ ++ +L TVCEEA CPNIGECWS G TAT ML
Sbjct: 27 REKKPEWLKVTIPTGQVFTEVRKIVKEHRLHTVCEEAMCPNIGECWSRG-----TATFML 81
Query: 127 MGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLH 186
MG CTR C FC+V T LD +EPR+ A ++ + Y+VLTSVDRDDLPDGG+ H
Sbjct: 82 MGHICTRACRFCAVDTGNPMGKLDLDEPRSVADSVRLMDLKYVVLTSVDRDDLPDGGAYH 141
Query: 187 FAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPR 246
FA+TVK IK++N VE L PDF CV V SG+D +A N+ETV RLT VRD R
Sbjct: 142 FAKTVKAIKEVNPQTRVEALTPDFGGNTACVDLVLDSGVDTYAQNLETVRRLTHPVRDIR 201
Query: 247 AGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQP 306
A Y +TL VL AK+ PD+ITK+S+MLGLGET ++ + M D R AGVD +T GQY++P
Sbjct: 202 ASYDRTLSVLAHAKQARPDVITKTSLMLGLGETREEIREAMADCRAAGVDVLTFGQYLRP 261
Query: 307 TKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRA 349
T HL V Y++PA F + G QLGFL V SG LVRSSY+A
Sbjct: 262 TMHHLPVERYISPAEFDEIREEGMQLGFLEVVSGPLVRSSYKA 304
>UniRef50_Q9Y9E3 Cluster: Probable lipoyl synthase; n=4; cellular
organisms|Rep: Probable lipoyl synthase - Aeropyrum
pernix
Length = 293
Score = 287 bits (705), Expect = 2e-76
Identities = 142/274 (51%), Positives = 192/274 (70%), Gaps = 8/274 (2%)
Query: 86 EIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRGCMFCSVKTSRN 145
++ + + L ++TVCE A CPNI CW G TAT M+MGDTCTRGC FC VK
Sbjct: 18 KVARLVAGLGVATVCEGALCPNIFTCW-----GEGTATFMIMGDTCTRGCRFCYVKKGV- 71
Query: 146 PPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAETVKEIKKLNKDILVEC 205
P PLDP EP A A++ G+ Y+ LTSVDRDDLPDGG+ HFA TV+ IK+L D +VE
Sbjct: 72 PEPLDPLEPYKVALAVDALGLDYVTLTSVDRDDLPDGGASHFAATVRAIKRLRPDTIVEA 131
Query: 206 LVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPD 265
L+PDF+ V V VA+SGL+V AHN+ETVERLTP VRD RAGYRQ+L+VL++AKE
Sbjct: 132 LIPDFQGVEEHVRLVAASGLEVLAHNIETVERLTPLVRDRRAGYRQSLRVLEIAKE--EG 189
Query: 266 LITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPARFQQW 325
++TKSSI+LGLGE ++V + M+DLR GVD + L QY +P++K L V + + + F++
Sbjct: 190 VVTKSSILLGLGEDKSEVIEAMRDLRSVGVDILVLSQYYRPSRKQLPVAKRYSLSEFREL 249
Query: 326 EARGRQLGFLYVASGALVRSSYRAGEFFISAVLR 359
+G ++GF YV + L R+S++A E +++AV R
Sbjct: 250 AEKGLRMGFAYVVAHPLARTSFKAKEAYLAAVRR 283
>UniRef50_Q0W150 Cluster: Putative lipoate synthetase; n=1;
uncultured methanogenic archaeon RC-I|Rep: Putative
lipoate synthetase - Uncultured methanogenic archaeon
RC-I
Length = 296
Score = 280 bits (686), Expect = 5e-74
Identities = 130/291 (44%), Positives = 183/291 (62%), Gaps = 5/291 (1%)
Query: 71 PPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDT 130
P WLK +P K+ +K ++ L+TVC A CPN ECW GG T M++G+T
Sbjct: 9 PDWLKVRLPRTDKYGAVKDVIKKYNLNTVCSSAMCPNAFECWDGG-----CLTFMVLGNT 63
Query: 131 CTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAET 190
CTR C FC+V PLD EP+ A A + Y+V+TSVDRDDLPD G+ H+A
Sbjct: 64 CTRACRFCTVTHGPAGEPLDSNEPQRLAAAAKELDLSYVVITSVDRDDLPDYGAGHYAAC 123
Query: 191 VKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYR 250
++ +K+ VE ++PDF + +V + DV +HN+ETVERL+P VRD RAGY
Sbjct: 124 IRAVKEQLPGARVEAIIPDFTGRLDLLEQVVDARPDVISHNIETVERLSPSVRDRRAGYY 183
Query: 251 QTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKH 310
++L VL+ K +NP ++TKSS++LG+GE D ++++ + DL+EA VD VTLGQY++P+ +
Sbjct: 184 RSLDVLRDVKRVNPHMLTKSSLLLGMGEEDIEIKEALHDLQEARVDIVTLGQYLRPSIRQ 243
Query: 311 LKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRDR 361
V YV P F + GR LGF YVA+G VR+SYRAGE ++S + R
Sbjct: 244 WPVHRYVAPGEFSELAEYGRSLGFKYVAAGPFVRTSYRAGEQYVSVIADSR 294
>UniRef50_Q4UK97 Cluster: Lipoyl synthase; n=131; Bacteria|Rep:
Lipoyl synthase - Rickettsia felis (Rickettsia azadi)
Length = 301
Score = 278 bits (682), Expect = 1e-73
Identities = 137/283 (48%), Positives = 185/283 (65%), Gaps = 7/283 (2%)
Query: 71 PPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDT 130
P W+K P +++ K +++L+L+TVCEEA CPNIGECWS KH AT+M++G
Sbjct: 8 PDWIKVKAPNSAEYYNTKDLIKNLRLNTVCEEAACPNIGECWSK-KH----ATVMILGSV 62
Query: 131 CTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAET 190
CTR C FC+VKT R P LDP EP+ A A+ + ++V+TSVDRDDL DGG+ HFAE
Sbjct: 63 CTRACRFCNVKTGR-PDLLDPHEPQRLAEAVQKLNLKHVVITSVDRDDLDDGGATHFAEC 121
Query: 191 VKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYR 250
+ EI+K + + +E L PDF G +A++ DVF HNVETV L +R P A Y
Sbjct: 122 ISEIRKSSPNTTIEILTPDFLRKEGAAEIIANAKPDVFNHNVETVPSLYKTIR-PGARYY 180
Query: 251 QTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKH 310
+L +L K+++P++ TKS +M+GLGE ++V Q M DLREA VD +T+GQY+QPTK H
Sbjct: 181 NSLSLLHNIKKLSPEIFTKSGMMVGLGEEISEVIQVMDDLREAKVDFLTIGQYLQPTKNH 240
Query: 311 LKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFF 353
+V +YVTP F+ E R GFL V++ L RSSY A E F
Sbjct: 241 AEVAKYVTPEEFKYLERIARTKGFLMVSATPLTRSSYHADEDF 283
>UniRef50_Q8R9E1 Cluster: Lipoyl synthase; n=31; cellular
organisms|Rep: Lipoyl synthase - Thermoanaerobacter
tengcongensis
Length = 284
Score = 275 bits (675), Expect = 1e-72
Identities = 138/282 (48%), Positives = 192/282 (68%), Gaps = 9/282 (3%)
Query: 68 LRLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLM 127
+R P WLK I N ++ L+++ L+TVC+ A CPN+GEC++ TAT M+M
Sbjct: 3 VRKPEWLKVRI-LSEDLNRMEAFLKNMALNTVCQSANCPNMGECFA-----RRTATFMIM 56
Query: 128 GDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHF 187
G+ CTR C FC+V+ +P PLD EEPR A A G+ ++V+TSV RDDLPDGG+ HF
Sbjct: 57 GNICTRNCRFCAVEKG-HPQPLDEEEPRRVAEAARRLGLRHVVVTSVTRDDLPDGGASHF 115
Query: 188 AETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRA 247
A+T+ E+KKL + VE LVPDF + V + DV HNVETV RL VR P+A
Sbjct: 116 AKTIYELKKL-PGVTVEVLVPDFMGNEEAIRTVVEAKPDVINHNVETVPRLYSRVR-PKA 173
Query: 248 GYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPT 307
Y ++L +L+ KE++P ++TKS IM+GLGET+ +V + MKDLR+ D +T+GQY++P+
Sbjct: 174 DYIRSLNLLKKVKELDPLILTKSGIMVGLGETEEEVIEVMKDLRDIDCDMMTIGQYLRPS 233
Query: 308 KKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRA 349
KH++V EYVTP +F+++E G +LGF +VASG LVRSSY A
Sbjct: 234 HKHIEVAEYVTPEQFKRYEEIGYKLGFKHVASGPLVRSSYHA 275
>UniRef50_Q4JBV4 Cluster: Probable lipoyl synthase; n=4; cellular
organisms|Rep: Probable lipoyl synthase - Sulfolobus
acidocaldarius
Length = 286
Score = 270 bits (663), Expect = 3e-71
Identities = 137/290 (47%), Positives = 184/290 (63%), Gaps = 10/290 (3%)
Query: 75 KTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRG 134
+ + F ++ + + +STVCEEA CPNI ECW G+ TAT M+MGD CTRG
Sbjct: 4 EVVVRINENFKKLSRIVSEKGISTVCEEALCPNIMECW-----GSGTATFMIMGDICTRG 58
Query: 135 CMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAETVKEI 194
C FC VK + P LD EEP A A+ G+ Y+V+TSVDRDDL DGG+ HF++ VK +
Sbjct: 59 CRFCYVKKGK-PVLLDHEEPIKVAEAVREMGLDYVVITSVDRDDLADGGASHFSQVVKAV 117
Query: 195 KKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLK 254
K++N D++VE L PDF + V +V SG+DVFAHNVETV LTP VRD RA Y Q+L+
Sbjct: 118 KEMNPDVIVEVLTPDFMGNKELVEKVIGSGVDVFAHNVETVRSLTPLVRDARASYEQSLR 177
Query: 255 VLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVF 314
VL AK + + KSSI+LGLGE+ +V +TMKDLR GVD + L QYM+P+ K L+V
Sbjct: 178 VLSYAKNV----VKKSSILLGLGESLEEVVETMKDLRNVGVDILVLSQYMRPSIKQLEVK 233
Query: 315 EYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRDRKVN 364
+ +++ E LGF YV + R+SYRA E ++ A+ + N
Sbjct: 234 KRYNMEEYKELEKIAYSLGFSYVVALPHARTSYRAKEAYLRAMANVKNNN 283
>UniRef50_Q028Q9 Cluster: Lipoic acid synthetase precursor; n=2;
Bacteria|Rep: Lipoic acid synthetase precursor -
Solibacter usitatus (strain Ellin6076)
Length = 308
Score = 268 bits (656), Expect = 2e-70
Identities = 141/286 (49%), Positives = 178/286 (62%), Gaps = 9/286 (3%)
Query: 67 RLRLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIML 126
R RLP W + + N +K+ LR LKL TVCEEARCPNI EC+ G AT M+
Sbjct: 17 RARLPEWARKSKTHFQSLNHLKRGLRELKLHTVCEEARCPNIHECFHRG-----AATFMI 71
Query: 127 MGDTCTRGCMFCSVKT---SRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGG 183
+GD CTRGC FCSV+ ++ LD EP N A + Y+V+TSV+RDDLPDGG
Sbjct: 72 LGDLCTRGCGFCSVRKLNPRKHDVRLDENEPANVARMAREMKLRYVVITSVNRDDLPDGG 131
Query: 184 SLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVR 243
S HFAETV+E++K + VE L PDF VARV +G VF HN+ETV RL VR
Sbjct: 132 SRHFAETVREVRKALPEARVEVLTPDFCGDLDAVARVLDAGPHVFNHNMETVPRLYARVR 191
Query: 244 DPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQY 303
P+A YRQ+L VL A+ ++ KS M+GLGE +VE ++DL EAG T+GQY
Sbjct: 192 -PQAEYRQSLDVLAFARRFAEGVLVKSGFMVGLGERADEVEALLRDLHEAGTQIATIGQY 250
Query: 304 MQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRA 349
+QPT+++L V E+V P +F+ W G LGF V SG LVRSSY A
Sbjct: 251 LQPTRRNLPVEEFVEPHQFEAWRDYGMGLGFQAVFSGPLVRSSYMA 296
>UniRef50_Q8ERL8 Cluster: Lipoyl synthase; n=51; Bacteria|Rep:
Lipoyl synthase - Oceanobacillus iheyensis
Length = 314
Score = 267 bits (654), Expect = 4e-70
Identities = 140/298 (46%), Positives = 187/298 (62%), Gaps = 6/298 (2%)
Query: 64 ESERLRLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTAT 123
+ +R P WLKT I T + +K+ +R +L+TVCEEARCPN+ ECWS K TAT
Sbjct: 4 QQTHVRKPDWLKTRINTNKSYRNLKKLMRDNRLNTVCEEARCPNLHECWSERK----TAT 59
Query: 124 IMLMGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGG 183
M++GDTCTRGC FC+VKT P LD EP A ++ G+ ++V+T+V RDDL DGG
Sbjct: 60 FMILGDTCTRGCRFCAVKTGL-PNELDWGEPERVADSVTVMGLKHVVVTAVARDDLNDGG 118
Query: 184 SLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVR 243
+ FAETV+ I++ N +E L D + + + SG D+F HN+ETV RLT VR
Sbjct: 119 AAVFAETVRAIRRKNPGCTIEILPSDMKGDYESLHTLMDSGPDIFNHNIETVRRLTKRVR 178
Query: 244 DPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQY 303
RA Y ++L++L+ KEI P+ TKSSIM+GLGE ++ Q M DL VD VTLGQY
Sbjct: 179 -ARAMYDRSLELLRRVKEIAPNTPTKSSIMVGLGEEKDEIIQAMDDLLAHNVDIVTLGQY 237
Query: 304 MQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRDR 361
+QPTKKHL+V Y P F++ + + GF + SG LVRSSY A E +A + R
Sbjct: 238 LQPTKKHLEVVRYYHPDEFEELKNIALEKGFSHCESGPLVRSSYHADEQVSNAAAQRR 295
>UniRef50_Q8YWC1 Cluster: Lipoyl synthase 1; n=18;
Cyanobacteria|Rep: Lipoyl synthase 1 - Anabaena sp.
(strain PCC 7120)
Length = 291
Score = 264 bits (646), Expect = 3e-69
Identities = 123/279 (44%), Positives = 176/279 (63%), Gaps = 6/279 (2%)
Query: 71 PPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDT 130
P WL+ P + +K+ LR L L+TVCEEA CPNIGEC+ G TAT ++MG
Sbjct: 5 PDWLRVKAPQWERVGNVKEILRDLALNTVCEEASCPNIGECFQAG-----TATFLIMGPA 59
Query: 131 CTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAET 190
CTR C +C + + P LDP EP A A+ + ++V+TSV+RDDLPDGG+ F +
Sbjct: 60 CTRACPYCDIDFEKKPKALDPTEPTRLAEAVRRMRLNHVVITSVNRDDLPDGGASQFVKC 119
Query: 191 VKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYR 250
+ E++ ++ +E L+PD + + + +V HN ET+ RL VR P+ Y
Sbjct: 120 IAEVRAVSPQTTIEVLIPDLCGNWEALRIILQASPEVLNHNTETIPRLYRRVR-PQGNYD 178
Query: 251 QTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKH 310
+TL++LQ +++I P L TKS IM+GLGET+A+V Q M+DLR D +T+GQY+QP++KH
Sbjct: 179 RTLELLQRSRQIAPWLYTKSGIMVGLGETNAEVRQVMQDLRAVDCDILTIGQYLQPSQKH 238
Query: 311 LKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRA 349
L+V ++VTP +F W+ G +LGFL V S L RSSY A
Sbjct: 239 LQVNDFVTPEQFAAWQVYGEELGFLQVVSSPLTRSSYHA 277
>UniRef50_A1HSS2 Cluster: Lipoic acid synthetase; n=2; Bacteria|Rep:
Lipoic acid synthetase - Thermosinus carboxydivorans
Nor1
Length = 294
Score = 262 bits (643), Expect = 8e-69
Identities = 139/294 (47%), Positives = 185/294 (62%), Gaps = 14/294 (4%)
Query: 67 RLRLPPWLKTTIPTGSKFNE------IKQQLRSLKLSTVCEEARCPNIGECWSGGKHGAS 120
R +P WL+ + + + +L +L TVC+ ARCPN G C+S HG
Sbjct: 3 RTTVPAWLRAMVRDAKRADNPALHALTAGRLAGYRLHTVCDGARCPNKGSCYS---HG-- 57
Query: 121 TATIMLMGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLP 180
TAT +++G+TCTR C FC+V R PP +DPEEPR A A+ G+ ++V+TSV RDDLP
Sbjct: 58 TATFLILGNTCTRSCAFCAVDHGR-PPAVDPEEPRRLAAAVAEMGLTHVVVTSVTRDDLP 116
Query: 181 DGGSLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTP 240
DGG+ FA + E++KL VE L PDFR +A V ++G +VFAHNVETV RL
Sbjct: 117 DGGAGQFAAVINELRKLPGRPRVEVLTPDFRGAPAALATVLAAGPEVFAHNVETVPRLYL 176
Query: 241 FVRDPRAGYRQTLKVL-QMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVT 299
VR P A YR+++ +L Q A+ P K+ IMLGLGE +A+V ++D+R AGV +T
Sbjct: 177 AVR-PGAEYRRSVNLLAQAARTAKPGTEIKTGIMLGLGEEEAEVMAVLEDVRAAGVTMIT 235
Query: 300 LGQYMQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFF 353
LGQY+ PT +H V YV PA F +W GRQ+GF VA+G LVRSSY AGEF+
Sbjct: 236 LGQYLAPTGRHYPVQRYVPPAEFAKWAEVGRQMGFKSVAAGPLVRSSYHAGEFY 289
>UniRef50_A6DU97 Cluster: Lipoyl synthase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Lipoyl synthase - Lentisphaera
araneosa HTCC2155
Length = 299
Score = 262 bits (642), Expect = 1e-68
Identities = 131/302 (43%), Positives = 194/302 (64%), Gaps = 9/302 (2%)
Query: 64 ESERLRLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTAT 123
E + RLP W++ + G +E+ ++LR +L+TVCEEA+CPN+ ECW TAT
Sbjct: 3 EKNQKRLPEWIRVKVNRGGNRDELNKELRGRQLNTVCEEAKCPNLAECWH-----ERTAT 57
Query: 124 IMLMGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGG 183
ML+G CTR C FC++ ++ PP DP+EP N A + Y+V+TSV RDDL D G
Sbjct: 58 FMLLGVNCTRACRFCAIGYNKPEPP-DPKEPENVADTAAKMDLEYVVITSVARDDLEDEG 116
Query: 184 SLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVR 243
S FA+T++ +++ +E L PDF + + VF HN+ET ERL+P +R
Sbjct: 117 SDQFAKTIRAVREKLPQAGIEVLTPDFNGKEDLIRMTLDAMPTVFNHNLETCERLSPPIR 176
Query: 244 DPRAGYRQTLKVLQMAKEINPD-LITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQ 302
RA Y+++L+VL+ AK + ++TKS IM+GLGETD +V Q + DL EA VD +T+GQ
Sbjct: 177 G-RAKYKRSLEVLKNAKAWSQGKVLTKSGIMVGLGETDEEVIQCIHDLYEANVDIITIGQ 235
Query: 303 YMQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRDRK 362
Y+ P++KH K+ YV P +F+ W+ +LGF VASG +VRSSY+AG+ I+A L++++
Sbjct: 236 YLPPSRKHWKLDRYVRPEQFEDWKEYAEKLGFNAVASGPMVRSSYKAGQ-LITAKLQEQQ 294
Query: 363 VN 364
+N
Sbjct: 295 LN 296
>UniRef50_Q7VKB1 Cluster: Lipoyl synthase; n=9; cellular
organisms|Rep: Lipoyl synthase - Haemophilus ducreyi
Length = 330
Score = 262 bits (641), Expect = 1e-68
Identities = 136/288 (47%), Positives = 187/288 (64%), Gaps = 9/288 (3%)
Query: 64 ESERLRLPPWLKTTIPTGS-KFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTA 122
+ E L+ P W+K +PT S K + IK +R L +VCEEA CPN+ EC++ HG TA
Sbjct: 40 DQELLKKPEWMKIKLPTNSAKIDSIKYGMRRHGLHSVCEEASCPNLHECFN---HG--TA 94
Query: 123 TIMLMGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDG 182
T M+MG CTR C FC V + P PLDP EPR A + + Y+V+TSVDRDDL D
Sbjct: 95 TFMIMGAICTRRCPFCDVAHGK-PLPLDPYEPRKVAETVQDMKLKYVVITSVDRDDLADR 153
Query: 183 GSLHFAETVKEIKKLNKDILVECLVPDFRA-VRGCVARVASSGLDVFAHNVETVERLTPF 241
G+ HFA TV+EIK LN + VE LVPDFR V VA + + DVF HN+E V RL
Sbjct: 154 GAAHFAATVREIKALNPECKVEILVPDFRGRVEQAVAILKQNPPDVFNHNLENVPRLYRE 213
Query: 242 VRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLG 301
+R P A Y+ +L++L++ K+ P++ TKS +M+GLGET+ ++ M+DLR+ GV +T+G
Sbjct: 214 IR-PGADYKWSLELLKIFKQEFPNIPTKSGLMVGLGETNEEILAVMQDLRDHGVTMLTVG 272
Query: 302 QYMQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRA 349
QY+QP++ HL+V YV PA F+ + + ++GF + A G VRSSY A
Sbjct: 273 QYLQPSRHHLRVERYVPPAEFEMFRSEAEKMGFEHAACGPFVRSSYHA 320
>UniRef50_Q9PDW0 Cluster: Lipoyl synthase; n=257; Bacteria|Rep:
Lipoyl synthase - Xylella fastidiosa
Length = 373
Score = 260 bits (636), Expect = 5e-68
Identities = 140/286 (48%), Positives = 181/286 (63%), Gaps = 12/286 (4%)
Query: 68 LRLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLM 127
LR P W++ IP+G+ +K +LR +L TVCEEA CPNI EC+S HG TAT M++
Sbjct: 49 LRKPSWIRVRIPSGNAVQSLKAKLRENRLVTVCEEAACPNIHECFS---HG--TATFMIL 103
Query: 128 GDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHF 187
G+ CTR C FC V R PP DPEEP + A + G+ Y+V+TSVDRDDL DGG+ HF
Sbjct: 104 GEVCTRRCSFCDVAHGRPKPP-DPEEPISLARTVAEMGLKYVVVTSVDRDDLRDGGAQHF 162
Query: 188 AETVKEIKKLNKDILVECLVPDFRAVRGCVAR----VASSGLDVFAHNVETVERLTPFVR 243
+ + I++ +E L PDFR +G + R +A+ DVF HNVETV L P VR
Sbjct: 163 VDCIAAIRQSAPQTRIEILTPDFRG-KGRMDRALDILAACPPDVFNHNVETVPALYPNVR 221
Query: 244 DPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQY 303
P A Y+ +L +L+ K +P + TKS IMLGLGET QV+ T++DLR VD VT+GQY
Sbjct: 222 -PGADYQWSLTLLKRFKAQHPQVPTKSGIMLGLGETLDQVQATLRDLRAHDVDMVTIGQY 280
Query: 304 MQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRA 349
+QPT H V Y TP ++ E G LGF +VASG +VRSSY A
Sbjct: 281 LQPTSHHHPVLRYWTPDEYKALEEYGMALGFSHVASGPMVRSSYHA 326
>UniRef50_Q8DL83 Cluster: Lipoyl synthase 2; n=7; Bacteria|Rep:
Lipoyl synthase 2 - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 298
Score = 252 bits (616), Expect = 1e-65
Identities = 117/279 (41%), Positives = 174/279 (62%), Gaps = 6/279 (2%)
Query: 71 PPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDT 130
P WL+ P + +K+ LR L L+TVCEEA CPNIGEC+ G TAT ++MG
Sbjct: 5 PEWLRVKAPQWQRVGSVKELLRDLNLNTVCEEASCPNIGECFYQG-----TATFLMMGPA 59
Query: 131 CTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAET 190
CTR C +C + + P PLDP EP+ A A+ + ++V+TSV+RDDL DGG+ F T
Sbjct: 60 CTRACPYCDIDFEKKPLPLDPTEPQRLAEAVVRMRLNHVVITSVNRDDLADGGASQFVAT 119
Query: 191 VKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYR 250
++ +++ + +E L+PD + ++ ++G +V HN ETV RL VR P+ Y+
Sbjct: 120 IEAVRQRSPQTTIEVLIPDLCGNWQALDQILAAGPEVLNHNTETVPRLYRRVR-PQGNYQ 178
Query: 251 QTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKH 310
++L++LQ ++ P + +KS IM+GLGET +V M+DLR+ G D +T+GQY+QP+ KH
Sbjct: 179 RSLELLQRVRDRAPWIYSKSGIMVGLGETSEEVVALMQDLRQVGCDILTIGQYLQPSPKH 238
Query: 311 LKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRA 349
L V ++ P +F++W G +GFL V S L RSSY A
Sbjct: 239 LAVQAFIPPEQFEEWRRLGESMGFLQVVSSPLTRSSYHA 277
>UniRef50_A5MZI9 Cluster: LipA2; n=1; Clostridium kluyveri DSM
555|Rep: LipA2 - Clostridium kluyveri DSM 555
Length = 287
Score = 251 bits (615), Expect = 2e-65
Identities = 124/281 (44%), Positives = 181/281 (64%), Gaps = 7/281 (2%)
Query: 71 PPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDT 130
P WLK +P +++ +R+L L TVCE A CPNIG+C+ +STAT M++G+T
Sbjct: 5 PEWLKMKVPDEKVLTKMENMVRNLSLHTVCESAVCPNIGKCFK-----SSTATFMVLGNT 59
Query: 131 CTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAET 190
CTR C FC+V +P PL+ EEP+N A A G+ + V+TSV RDDL DGG+ HF E
Sbjct: 60 CTRNCRFCAVNKG-HPEPLNIEEPKNVAIASKKLGLKHTVITSVTRDDLEDGGADHFVEI 118
Query: 191 VKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYR 250
+K ++K N +E L+PD R + ++ + D+ HNVETVE L VR P A Y
Sbjct: 119 IKRMRKENPQSTIELLIPDLRGNWKSLKKIIDAKPDILNHNVETVEILYGKVR-PTAVYS 177
Query: 251 QTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKH 310
+++++L+ K + + TKS IM+GLGET+ QV + M DL E G D +T+GQY++P+K H
Sbjct: 178 RSIELLRQVKIFDKGVYTKSGIMVGLGETEEQVMKVMDDLLEVGCDIMTIGQYLRPSKSH 237
Query: 311 LKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGE 351
+ V+EY++P +F++++ + GF +VAS VRSSYRA E
Sbjct: 238 IPVYEYISPEQFEKYKQIAIEKGFKFVASAPYVRSSYRAYE 278
>UniRef50_Q8ZUR9 Cluster: Probable lipoyl synthase; n=4; cellular
organisms|Rep: Probable lipoyl synthase - Pyrobaculum
aerophilum
Length = 290
Score = 251 bits (614), Expect = 2e-65
Identities = 135/290 (46%), Positives = 177/290 (61%), Gaps = 10/290 (3%)
Query: 70 LPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGD 129
+P W+ K +++ L + TVCE A+CPNI CW G TAT M++G+
Sbjct: 2 IPSWVSLRAGDYEKIINVRRALSRHGIYTVCEGAKCPNIFHCW-----GEGTATFMILGE 56
Query: 130 TCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAE 189
CTR C FC+V+T +D E A+ G+ Y+V+TSV RDDLPDGG+ FA
Sbjct: 57 VCTRACRFCAVRTGNPRGYVDWGEVDRLVEAVRELGLKYVVVTSVARDDLPDGGASVFAA 116
Query: 190 TVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGY 249
VK+++++ +VE LVPDF V V SSG DVFAHNVETV RLTP VRD RAGY
Sbjct: 117 VVKKLREVG--CVVEVLVPDFGGSPASVKTVVSSGPDVFAHNVETVRRLTPLVRDRRAGY 174
Query: 250 RQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQP--T 307
++L VL+ AKE L TKS +MLGLGET +V +T++DLR A VD VT+GQY++P +
Sbjct: 175 ERSLSVLKYAKEFGAPL-TKSGLMLGLGETFEEVVETLEDLRRADVDIVTIGQYIKPSGS 233
Query: 308 KKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAV 357
+HL Y TP F + + LGF VASG LVRSSY+A + A+
Sbjct: 234 PRHLNPVRYATPEEFAKIKEVAVSLGFKAVASGPLVRSSYKAYSLYREAL 283
>UniRef50_Q0LDD9 Cluster: Lipoic acid synthetase; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Lipoic acid synthetase -
Herpetosiphon aurantiacus ATCC 23779
Length = 306
Score = 249 bits (610), Expect = 8e-65
Identities = 125/285 (43%), Positives = 175/285 (61%), Gaps = 8/285 (2%)
Query: 67 RLRLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIML 126
R R P WL+ + + ++Q LR L L+TVCEEA CPNI EC+ HG TAT M+
Sbjct: 7 RQRKPEWLRKPV-LSPELRNVRQLLRDLNLNTVCEEASCPNIAECFG---HG--TATFMI 60
Query: 127 MGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLH 186
GD CTR C +C V T + P PLDP EP N A A G+ Y+V+T+V RDD+ DGG+ H
Sbjct: 61 GGDRCTRRCHYCDVTTGK-PFPLDPREPSNVAEAAARLGLKYVVVTAVARDDVKDGGARH 119
Query: 187 FAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPR 246
FA T+ I++ + VE L+PDF+ + V + V HN+ETV + VR P+
Sbjct: 120 FARTISAIRQRLPEAEVEVLIPDFKGEAEALKTVLDAEPHVLNHNIETVRSVFKSVR-PQ 178
Query: 247 AGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQP 306
Y ++L++L ++E P + TKS M+GLGET ++ QTM DL+ GV+ VT+GQY+QP
Sbjct: 179 GDYDRSLELLARSREFAPQITTKSGFMVGLGETTDEIYQTMDDLKHVGVELVTIGQYLQP 238
Query: 307 TKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGE 351
+ H+ V EY+ P R+ + G+QLGF +G +RSS+ AGE
Sbjct: 239 SLNHVAVSEYIPPERYGLYRDHGQQLGFRATFAGPFIRSSFHAGE 283
>UniRef50_P61199 Cluster: Lipoyl synthase; n=4; Bacteria|Rep: Lipoyl
synthase - Treponema denticola
Length = 290
Score = 244 bits (598), Expect = 2e-63
Identities = 121/287 (42%), Positives = 181/287 (63%), Gaps = 9/287 (3%)
Query: 69 RLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMG 128
R P WLK +PTG E+ ++ KL+T+C +CPN GECW G TAT M+ G
Sbjct: 13 RKPDWLKIKLPTGELSQEVSNTIKIHKLNTICTSGKCPNQGECWRCG-----TATFMICG 67
Query: 129 DTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFA 188
+ CTR C FC+V T P PL+P EP A ++ + ++VLTSVDRDD+ D G+ H+
Sbjct: 68 NICTRACKFCNVPTGC-PLPLNPNEPMEIAQSVEALKLKHVVLTSVDRDDIKDFGASHWV 126
Query: 189 ETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAG 248
+ ++ +K+ ++ +E L+PDF+ V+ + + +V +HN+ETV RL+P VR RA
Sbjct: 127 KVIRAVKQKTPNVTMEVLIPDFQGHEDLVSMIIEAKPEVISHNLETVRRLSPHVRS-RAT 185
Query: 249 YRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTK 308
Y +LKVL+ + L+ KS IMLGLGET A++ +TM DLR+ +T+GQY++P+
Sbjct: 186 YDTSLKVLKQIADSG--LVCKSGIMLGLGETRAEILETMDDLRKINCKVMTIGQYLRPSI 243
Query: 309 KHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFIS 355
K+++V EYV P F++++ G + GF +V SG LVRSSY A + +S
Sbjct: 244 KNIEVKEYVRPEVFEEYKQIGLEKGFSFVESGPLVRSSYHAEKHVLS 290
>UniRef50_Q3ARP5 Cluster: Lipoate synthase; n=11; Bacteria|Rep:
Lipoate synthase - Chlorobium chlorochromatii (strain
CaD3)
Length = 300
Score = 243 bits (594), Expect = 7e-63
Identities = 123/284 (43%), Positives = 171/284 (60%), Gaps = 7/284 (2%)
Query: 69 RLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMG 128
R P WLK + +G+ F +Q L L TVC A CPN+ ECWS G TAT +L+G
Sbjct: 14 RKPEWLKIKMASGASFAATRQLLNRHSLHTVCRSALCPNLQECWSRG-----TATFLLLG 68
Query: 129 DTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFA 188
+TCTR C FC+V + PP D +EP+ A AI + + VLTSV RDDLPDGG+ H+
Sbjct: 69 NTCTRSCTFCAVSKASAPPAPDSDEPQKIAEAIASMKLKHAVLTSVTRDDLPDGGANHWI 128
Query: 189 ETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAG 248
T++ I++ ++ +ECL+PDF+ + + V + DV HN+E+V L VR P+A
Sbjct: 129 ATMQAIRQRTPNVSLECLIPDFQHKKAALDSVMQATPDVLNHNIESVPSLYSTVR-PQAN 187
Query: 249 YRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTK 308
YR +L++L+ AKE L TKS +M+G+GE +VE T+ DL G D VT+GQY+QP+
Sbjct: 188 YRASLELLRYAKE-QHGLATKSGLMVGMGEERHEVEATLHDLAAHGCDMVTIGQYLQPSA 246
Query: 309 KHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEF 352
HL V YV P F+++ + G YV + VRSSY A F
Sbjct: 247 AHLPVARYVPPQEFEEYSTIAKNAGIRYVHAAPFVRSSYHAETF 290
>UniRef50_Q8F3V7 Cluster: Lipoyl synthase; n=4; Leptospira|Rep:
Lipoyl synthase - Leptospira interrogans
Length = 301
Score = 239 bits (586), Expect = 6e-62
Identities = 127/285 (44%), Positives = 173/285 (60%), Gaps = 13/285 (4%)
Query: 71 PPWLKTTI----PTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIML 126
P WLK + P + ++ L KL+TVCE A CPN+ CWS TAT ML
Sbjct: 20 PDWLKVKLAFPDPKNNPVAIVRNSLEEKKLNTVCESASCPNLNHCWS-----RKTATYML 74
Query: 127 MGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLH 186
GD CTR C +C V + + P PLDPEEP+ A + + ++V+TSV+RDDL DGG+ H
Sbjct: 75 GGDICTRRCSYCDVASGK-PFPLDPEEPKRIAESSIALDLRHVVITSVNRDDLEDGGAAH 133
Query: 187 FAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPR 246
FA+TVKEI+K D +E L+PD + + + + D+F HN+ETV+RL P V P+
Sbjct: 134 FAKTVKEIRKGLPDCKIELLIPDLKVKQEALEIIFECNPDIFNHNLETVKRLFPEVA-PQ 192
Query: 247 AGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQP 306
Y ++L VL++A +TKS ++LG+GET +V++ M+DL GV +TLGQY+QP
Sbjct: 193 KRYERSLDVLKIASA--RGFLTKSGLILGMGETLEEVKECMQDLASVGVSLLTLGQYLQP 250
Query: 307 TKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGE 351
T HL V EYV P F+ G+ +GF V SG LVRSSY A E
Sbjct: 251 TSTHLPVKEYVVPQVFKDLRIYGKSIGFKGVFSGPLVRSSYHADE 295
>UniRef50_O67368 Cluster: Lipoyl synthase; n=1; Aquifex
aeolicus|Rep: Lipoyl synthase - Aquifex aeolicus
Length = 276
Score = 237 bits (581), Expect = 2e-61
Identities = 123/274 (44%), Positives = 174/274 (63%), Gaps = 7/274 (2%)
Query: 82 SKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRGCMFCSVK 141
SK E+K+ LR +L TVCEE+RCPNI EC+ G TAT M++G+ CTR C FC+V+
Sbjct: 9 SKLYEVKKLLRKSRLYTVCEESRCPNISECF-----GNKTATFMILGNRCTRRCAFCNVE 63
Query: 142 TSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAETVKEIKKLNKDI 201
P +DPEEP A+ G+ Y+V+TSV RDDLPDGG+ HFA+ ++ +K+ +DI
Sbjct: 64 KGF-PKGVDPEEPYRLLEAVKTLGLKYVVITSVTRDDLPDGGASHFAKCIRVLKENIEDI 122
Query: 202 LVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKE 261
VE L+PDFR + + V V HNVETV RL P VR A Y+++L +L+ +KE
Sbjct: 123 KVEVLIPDFRGNKKALEVVLKEKPVVLNHNVETVPRLYPSVR-IGANYKRSLNILKWSKE 181
Query: 262 INPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPAR 321
I+ + TKS+++LG GE +V + M+DLR D + LGQY QP+ KH V +Y +
Sbjct: 182 IDKSVYTKSALILGFGERKEEVIKVMEDLRSVDCDFLVLGQYYQPSLKHHPVVKYYSEEE 241
Query: 322 FQQWEARGRQLGFLYVASGALVRSSYRAGEFFIS 355
F+++E G ++GF +V S RSSY+A E +S
Sbjct: 242 FKEFEEIGYEMGFKFVVSKPNARSSYKAFESLLS 275
>UniRef50_A6GIK5 Cluster: Lipoyl synthase; n=2; Bacteria|Rep: Lipoyl
synthase - Plesiocystis pacifica SIR-1
Length = 322
Score = 237 bits (579), Expect = 4e-61
Identities = 125/286 (43%), Positives = 175/286 (61%), Gaps = 9/286 (3%)
Query: 64 ESERLRLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTAT 123
++ R R P WL+ +P G ++E+K+++ L L TVC+ A CPNIGECW+ T
Sbjct: 21 KARRPRHPKWLRVPMPGGQAYSELKKRVNELNLHTVCQSASCPNIGECWNN-----KALT 75
Query: 124 IMLMGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGG 183
IM++G+ CTR C FC V T R P P+D EEPR A + + + V+TSVDRDDL DGG
Sbjct: 76 IMILGEICTRSCRFCDVATGR-PLPVDEEEPRRVATILAELELNHTVITSVDRDDLKDGG 134
Query: 184 SLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVR 243
+ +A T++ L + +E LVPDF+ V V ++ DVFAHN+ETV RL+ VR
Sbjct: 135 ASIWAATLEACHTLAPWMTIEVLVPDFKGQLADVDAVLAANPDVFAHNLETVPRLSREVR 194
Query: 244 DPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQY 303
+A Y ++ VL+ A+E +TK+ IMLGLGE +V + + +L + G+ +TLGQY
Sbjct: 195 -VQARYDRSYAVLRHAREAG--ALTKTGIMLGLGEELDEVREVITELGQLGLTILTLGQY 251
Query: 304 MQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRA 349
+QP+KKHL V YV P F R+ G ++ SG LVRSSY A
Sbjct: 252 LQPSKKHLPVARYVHPDEFAALAEFAREAGIAHIESGPLVRSSYHA 297
>UniRef50_Q821K6 Cluster: Lipoyl synthase; n=4; Chlamydiaceae|Rep:
Lipoyl synthase - Chlamydophila caviae
Length = 312
Score = 235 bits (575), Expect = 1e-60
Identities = 123/291 (42%), Positives = 174/291 (59%), Gaps = 7/291 (2%)
Query: 59 KREKGESERLRLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHG 118
K +G+ RLP WL+ +PTG F + ++ ++TVCEEA CPN CWS
Sbjct: 10 KPPQGKRFAERLPKWLRQVLPTGPVFAQTDTTIKRTGMATVCEEALCPNRACCWS----- 64
Query: 119 ASTATIMLMGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDD 178
TAT + +GD CTR C FC++ ++ P DPEEP+ A + + +IVLT V RDD
Sbjct: 65 RKTATYLALGDACTRRCGFCNIDFTKKPISPDPEEPQKIAESAKILQLKHIVLTMVARDD 124
Query: 179 LPDGGSLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERL 238
L DGG+ + + + + VE L DF+ + + SGL ++ HNVETVERL
Sbjct: 125 LEDGGASFLVRIIDTLHQELPESTVEVLASDFQGNIDALHTLLDSGLTIYNHNVETVERL 184
Query: 239 TPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCV 298
TP VR +A YR++L +L+ A PDL KS IM+GLGE +++V+QT+KDL + GV V
Sbjct: 185 TPVVRH-KATYRRSLFMLEQAAMYLPDLKIKSGIMVGLGEQESEVKQTLKDLADHGVKIV 243
Query: 299 TLGQYMQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRA 349
T+GQY++P++ H+ V YVTP F + G LG L+V +G VRSS+ A
Sbjct: 244 TIGQYLRPSRSHIPVKSYVTPETFDYYRTIGTSLG-LFVYAGPFVRSSFNA 293
>UniRef50_Q9PJI2 Cluster: Lipoyl synthase; n=4; Chlamydiales|Rep:
Lipoyl synthase - Chlamydia muridarum
Length = 308
Score = 231 bits (565), Expect = 2e-59
Identities = 116/293 (39%), Positives = 176/293 (60%), Gaps = 7/293 (2%)
Query: 69 RLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMG 128
R P WL+ +P G F+ +++ L TVCEEA CPN CWS +H TAT + +G
Sbjct: 17 RFPKWLRQKLPLGKVFSRTDGTIKNKGLPTVCEEASCPNRTHCWS--RH---TATYLALG 71
Query: 129 DTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFA 188
D CTR C FC + ++ P P DP+E A + G+ +IV+T V RDDL DGG+ A
Sbjct: 72 DACTRRCGFCDIDFTKKPLPPDPQEGEKIAASAKALGLKHIVITMVSRDDLEDGGADALA 131
Query: 189 ETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAG 248
+ + + +E L DF + + + + ++ HNVETVERL+P VR +A
Sbjct: 132 RIITTLHIELPEATIEVLASDFEGNIDALHHLLDARIAIYNHNVETVERLSPLVRH-KAT 190
Query: 249 YRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTK 308
YR++L +L+ A + PDL+ KS IM+GLGE +++++QT+KDL + GV VT+GQY++P++
Sbjct: 191 YRRSLMMLEQAAQYLPDLMIKSGIMVGLGEQESEIKQTLKDLADHGVKIVTIGQYLRPSR 250
Query: 309 KHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAVLRDR 361
+H+ V YV+P F + + G LG L++ +G VRSS+ A F + R+R
Sbjct: 251 RHIPVKSYVSPETFDYYRSVGEALG-LFIYAGPFVRSSFNADAVFEAMSQRER 302
>UniRef50_Q7VBJ3 Cluster: Lipoyl synthase 2; n=37;
Cyanobacteria|Rep: Lipoyl synthase 2 - Prochlorococcus
marinus
Length = 308
Score = 224 bits (547), Expect = 3e-57
Identities = 118/294 (40%), Positives = 175/294 (59%), Gaps = 21/294 (7%)
Query: 69 RLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMG 128
RLP W+K ++ T S+ +++ ++ +L+T+CEE RCPN GEC++ G TAT +L G
Sbjct: 18 RLPEWIKPSLGTASQLEKVQNLVKEYRLNTICEEGRCPNRGECYASG-----TATFLLGG 72
Query: 129 DTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFA 188
CTR C FC V+ P +DP E A A+ + Y+VLTSV RDDL D G++HF+
Sbjct: 73 SICTRSCAFCQVEKGMPPQNIDPNESIRVAKAVLKLQLKYVVLTSVARDDLDDHGAIHFS 132
Query: 189 ETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLD-------------VFAHNVETV 235
T+ I+K + +E L PDF GC+ ++ ++ + F HN+ETV
Sbjct: 133 RTIHAIRKTSPTTSIEVLTPDFWG--GCIDKIKATKIQRERLKIVLKAKPVCFNHNLETV 190
Query: 236 ERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGV 295
ERL VR A Y ++L++L+ ++EI+ ++ TKS +MLGLGE ++ QT+KDLR
Sbjct: 191 ERLQKEVRRG-ATYHRSLELLKASREIDNEIPTKSGLMLGLGERSDEIIQTLKDLRSVNC 249
Query: 296 DCVTLGQYMQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRA 349
VT+GQY++P+ H+ V +Y P F+ ++ LGF V SG LVRSSY A
Sbjct: 250 QQVTIGQYLRPSLAHIPVQKYWLPKDFEHFKRIAEGLGFKKVNSGPLVRSSYHA 303
>UniRef50_Q7UH37 Cluster: Lipoyl synthase; n=3;
Planctomycetaceae|Rep: Lipoyl synthase - Rhodopirellula
baltica
Length = 316
Score = 222 bits (542), Expect = 1e-56
Identities = 118/281 (41%), Positives = 161/281 (57%), Gaps = 6/281 (2%)
Query: 69 RLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMG 128
RLP WLK IP + + + L TVC+ A+CPN EC+S TAT M++G
Sbjct: 35 RLPRWLKRPIPKSNSNHLTDSLMEEYGLETVCDNAKCPNRMECYS-----QQTATFMVLG 89
Query: 129 DTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFA 188
+ CTR C FC+V R P +EP A A G+ ++V+TSV RDDLPDGG+ HF
Sbjct: 90 NVCTRPCGFCAVSRGRPPAAPAVDEPDRIAKAAERLGLKHVVITSVTRDDLPDGGADHFH 149
Query: 189 ETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAG 248
V +++ E L PDF + +ARV + VF HN+ETV RL VR P++
Sbjct: 150 NCVIAVRE-RTGATTEVLTPDFVHCKEALARVIEAKPTVFNHNMETVPRLYRRVRGPKSD 208
Query: 249 YRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTK 308
Y TL++++ K + ++ TKS +MLGLGE ++ + DLRE VD +TLGQY+QP +
Sbjct: 209 YAWTLEMMRQVKRYDAEVKTKSGLMLGLGEERGELLDALSDLREHDVDFLTLGQYLQPGE 268
Query: 309 KHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRA 349
K+L V YV P F + + +GF VASG VRSSY A
Sbjct: 269 KYLPVVRYVPPEEFDELADIAKSMGFKKVASGPFVRSSYHA 309
>UniRef50_P61194 Cluster: Lipoyl synthase; n=54; Bacteria|Rep:
Lipoyl synthase - Corynebacterium diphtheriae
Length = 349
Score = 217 bits (531), Expect = 3e-55
Identities = 110/287 (38%), Positives = 170/287 (59%), Gaps = 9/287 (3%)
Query: 71 PPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDT 130
P W++T + TG ++ ++K+++ L TVC+EA CPNI ECW + AT ++ G
Sbjct: 26 PRWIRTAVKTGPEYQDMKKKVSGASLHTVCQEAGCPNIHECWESRE-----ATFLIGGAN 80
Query: 131 CTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAET 190
C+R C FC + +++ P PLD +EPR A ++ + Y +T V RDDL D G+ +AE
Sbjct: 81 CSRRCDFCQINSAK-PEPLDRDEPRRVAESVREMQLNYSTITGVTRDDLEDEGAWLYAEV 139
Query: 191 VKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYR 250
V++I +LN VE L PDF + V + +VFAHN+ETV R+ +R P Y
Sbjct: 140 VRKIHELNPHTGVENLTPDFSGKPDLLQEVFEARPEVFAHNLETVPRIFKRIR-PAFRYE 198
Query: 251 QTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKH 310
++L V++ A++ L+TKS+++LG+GET ++ + DL AG D +T+ QY++P +
Sbjct: 199 RSLDVIRQARDFG--LVTKSNLILGMGETVDEIRDALVDLHSAGCDIITITQYLRPGPMY 256
Query: 311 LKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEFFISAV 357
+ +V P F R+LGF V SG LVRSSYRAG+ + A+
Sbjct: 257 HPIDRWVKPEEFIDHADFARELGFGAVMSGPLVRSSYRAGKLYAEAL 303
>UniRef50_P61196 Cluster: Lipoyl synthase; n=7; Bacteria|Rep: Lipoyl
synthase - Geobacter sulfurreducens
Length = 303
Score = 212 bits (517), Expect = 1e-53
Identities = 115/284 (40%), Positives = 163/284 (57%), Gaps = 9/284 (3%)
Query: 69 RLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMG 128
R P WL+ I + + + L L+L TVC EARCPNI EC+ + AT +++G
Sbjct: 5 RKPEWLRKKINPAAH-GAMDELLGELRLHTVCREARCPNITECFRERQ-----ATFLILG 58
Query: 129 DTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFA 188
CTR C FC+V T P P DP+EP A A+ + ++V+TS RDDLPDGG+ H+
Sbjct: 59 AECTRLCSFCNV-TKGEPLPPDPDEPARVAQAVVRLSLAHVVITSPTRDDLPDGGAGHYV 117
Query: 189 ETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAG 248
TV I ++ +VE L+PDF R +A V ++ + HNVETV RL + A
Sbjct: 118 ATVATIGRVAPATVVELLIPDFLGSRAALADVVAAAPRIIGHNVETVPRL--YAIRAGAD 175
Query: 249 YRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTK 308
Y ++L VL+ +E+ P TKS +MLGLGET+ +V M DLR ++LGQY+ P++
Sbjct: 176 YGRSLAVLRTLRELAPGCATKSGLMLGLGETEEEVLAVMADLRRVDCTYLSLGQYLAPSR 235
Query: 309 KHLKVFEYVTPARFQQWEARGRQLGFLYVASGALVRSSYRAGEF 352
H V E+V P F + + ++GF +V SG VRSSY A +
Sbjct: 236 FHHPVREFVLPETFDRLKELAEKMGFRHVESGPYVRSSYHAAGY 279
>UniRef50_A6Q3H7 Cluster: Lipoate synthase; n=1; Nitratiruptor sp.
SB155-2|Rep: Lipoate synthase - Nitratiruptor sp.
(strain SB155-2)
Length = 274
Score = 192 bits (467), Expect = 2e-47
Identities = 109/255 (42%), Positives = 152/255 (59%), Gaps = 11/255 (4%)
Query: 96 LSTVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRGCMFCSVKTSRNPPPLDPEEPR 155
L T+C A+CPNI EC+S G TAT M++G+ CTR C FC+V + P +D EP
Sbjct: 27 LHTICISAKCPNIVECFSRG-----TATFMILGNICTRRCRFCNVFHGK-PQEIDETEPT 80
Query: 156 NTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAETVKEIKKLNKDILVECLVPDFRAVRG 215
A A+ G+ Y+V+TSVDRDDL D GS F + I+K N VE L PDF+ +
Sbjct: 81 RIAKAVKEMGLSYVVITSVDRDDLSDFGSDQFYAVCQAIQKENPYTKVELLTPDFQGNKK 140
Query: 216 CVARVASSGLDVFAHNVETVERLTPFVRDPRAG-YRQTLKVLQMAKEINPDLITKSSIML 274
V +V + AHN+ETVE L F R AG Y+++L+VL+ + TKSS+M+
Sbjct: 141 AVQKVIDANPYKLAHNIETVEPL--FKRIKSAGSYKRSLEVLE--TYTTSGIKTKSSVMV 196
Query: 275 GLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPARFQQWEARGRQLGF 334
GLGET + ++ +DL +AGV +T+GQY+QP+ + KV +Y T F + ++ G
Sbjct: 197 GLGETKRDLIRSFQDLVQAGVSQLTIGQYLQPSSSNAKVQKYYTQEEFDELAHLAKECGI 256
Query: 335 LYVASGALVRSSYRA 349
+V SG LVRSSY A
Sbjct: 257 EHVISGILVRSSYYA 271
>UniRef50_Q01AS9 Cluster: Lipoic acid synthase; n=1; Ostreococcus
tauri|Rep: Lipoic acid synthase - Ostreococcus tauri
Length = 360
Score = 163 bits (395), Expect = 9e-39
Identities = 80/134 (59%), Positives = 98/134 (73%), Gaps = 1/134 (0%)
Query: 210 FRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITK 269
F+ VA +A SGLDVFAHNVETVERL VRDPRAGY Q+L VL+ AKE L+TK
Sbjct: 15 FQGDMDAVAHLARSGLDVFAHNVETVERLQKRVRDPRAGYEQSLSVLRHAKESKEGLVTK 74
Query: 270 SSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPARFQQWEARG 329
+SIMLGLGETD ++++ M+ +EAGVD TLGQY+QPT HL V E+VTP +F W+ G
Sbjct: 75 TSIMLGLGETDDEIKECMRACKEAGVDIFTLGQYLQPTSNHLPVSEFVTPEKFDYWKKFG 134
Query: 330 -RQLGFLYVASGAL 342
++GF YVASG L
Sbjct: 135 EEEIGFRYVASGPL 148
>UniRef50_Q6P5Q6 Cluster: LIAS protein; n=5; Catarrhini|Rep: LIAS
protein - Homo sapiens (Human)
Length = 142
Score = 136 bits (330), Expect = 6e-31
Identities = 62/102 (60%), Positives = 76/102 (74%), Gaps = 4/102 (3%)
Query: 27 DAIREKLKEGPNLTDFISEDRP--KNWDEYQGKLKREKGESERLRLPPWLKTTIPTGSKF 84
D +E L+ GP+L DF+S D WDEY+G LKR+KGE RLRLPPWLKT IP G +
Sbjct: 33 DKKKELLQNGPDLQDFVSGDLADRSTWDEYKGNLKRQKGE--RLRLPPWLKTEIPMGKNY 90
Query: 85 NEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIML 126
N++K LR+L L TVCEEARCPNIGECW GG++ +TATIM+
Sbjct: 91 NKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYATATATIMV 132
>UniRef50_A7R5C7 Cluster: Chromosome undetermined scaffold_937,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_937, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 241
Score = 121 bits (292), Expect = 3e-26
Identities = 57/111 (51%), Positives = 81/111 (72%), Gaps = 7/111 (6%)
Query: 26 LDAIREKLK-EGPNLTDFISEDRPKNWDEYQGKLKREKGESERLRLPPWLKTTIPTGSKF 84
L ++R +L E P+L+DF+ R + D+Y ++ +K + L P W+K +IP G+K+
Sbjct: 136 LASLRHRLAVESPSLSDFV---RLQTSDDYSVEVGTKK---KPLSKPKWMKESIPGGAKY 189
Query: 85 NEIKQQLRSLKLSTVCEEARCPNIGECWSGGKHGASTATIMLMGDTCTRGC 135
+IK++LR L L TVCEEARCPN+GECWSGG+ G +TATIM++GDTCTRGC
Sbjct: 190 TQIKKKLRQLNLHTVCEEARCPNMGECWSGGETGTATATIMILGDTCTRGC 240
>UniRef50_Q5BXH1 Cluster: SJCHGC04147 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04147 protein - Schistosoma
japonicum (Blood fluke)
Length = 169
Score = 116 bits (280), Expect = 7e-25
Identities = 63/139 (45%), Positives = 81/139 (58%), Gaps = 14/139 (10%)
Query: 4 NTIKKYKVT-KHLDFPRYKHSNKLDA------IREKLKEGPNLTDFI----SEDRPKNWD 52
N ++ Y T K DF K N + R+ + GP+ +F + P +
Sbjct: 34 NIVRSYSSTDKPTDFEETKKENIISTQQLPTNFRKSIANGPSFIEFTKLGNNNISPGDAS 93
Query: 53 EYQGKLKREKGESERLRLPPWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECW 112
QG L + + ERLRLP WLKT IP G +++QLRSLKL TVCEEARCPN+ ECW
Sbjct: 94 SSQGPLLKSE---ERLRLPEWLKTEIPCGGNVARLQKQLRSLKLHTVCEEARCPNLSECW 150
Query: 113 SGGKHGASTATIMLMGDTC 131
+GGK A+TATIM+MGDTC
Sbjct: 151 TGGKSAAATATIMIMGDTC 169
>UniRef50_Q3ERB0 Cluster: Lipoic acid synthetase; n=1; Bacillus
thuringiensis serovar israelensis ATCC 35646|Rep: Lipoic
acid synthetase - Bacillus thuringiensis serovar
israelensis ATCC 35646
Length = 117
Score = 50.0 bits (114), Expect = 1e-04
Identities = 21/38 (55%), Positives = 27/38 (71%)
Query: 287 MKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPARFQQ 324
+ DLR VD +TLGQY+QP+KKHL V +Y PA F +
Sbjct: 4 LDDLRANNVDILTLGQYLQPSKKHLPVIKYYPPAEFAE 41
>UniRef50_A3EVI4 Cluster: Biotin synthase; n=1; Leptospirillum sp.
Group II UBA|Rep: Biotin synthase - Leptospirillum sp.
Group II UBA
Length = 346
Score = 43.6 bits (98), Expect = 0.008
Identities = 44/175 (25%), Positives = 69/175 (39%), Gaps = 11/175 (6%)
Query: 131 CTRGCMFCSVKTSRNP-----PPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSL 185
C+ C FCS + P PE R TA G + + R L D +
Sbjct: 81 CSEDCHFCSQSSHHQTISPEFPLTPPETIRKTATLAKENGARRFCVATSGRG-LSDPSDV 139
Query: 186 HFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDP 245
+ I+ + D+ + R + + +GL+ HN+ET P +
Sbjct: 140 RGIS--RAIETVRNDVGIWSCATLGILSRSVLETLREAGLNRLHHNLETSREFFPNIVTT 197
Query: 246 RAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTL 300
A Y + + ++ AKE + S + GLGETDA ++ LRE VD V +
Sbjct: 198 HA-YEERIDTIRKAKE--QGISVCSGGIFGLGETDADRVGLLETLRELDVDSVPI 249
>UniRef50_A7HG97 Cluster: Biotin synthase; n=2;
Anaeromyxobacter|Rep: Biotin synthase - Anaeromyxobacter
sp. Fw109-5
Length = 368
Score = 41.1 bits (92), Expect = 0.044
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 5/118 (4%)
Query: 190 TVKE-IKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRDPRAG 248
T++E ++KL + VE + R+ ++GL + HN+ET V
Sbjct: 125 TIEEAVRKLRAETAVEPCASLGLVREPELVRLKAAGLMHYHHNLETARSFFENVCTTHT- 183
Query: 249 YRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQP 306
Y + L+ ++ AK L S +LG+GET Q + +RE G+DCV + ++ P
Sbjct: 184 YDEQLETIRAAKRQGLKLC--SGGILGMGETPEQRVELAATIRELGIDCVPM-NFLNP 238
>UniRef50_Q8EAH7 Cluster: Biotin synthase family protein; n=3;
Shewanella|Rep: Biotin synthase family protein -
Shewanella oneidensis
Length = 359
Score = 40.7 bits (91), Expect = 0.059
Identities = 43/185 (23%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Query: 124 IMLMGDTCTRGCMFCSVKTSRNPPP---LDPEEPRNTAHAINHWGVGYIVLTSVDRDDLP 180
I+ + C C +C ++T L EE N +I G+G +VL S DD
Sbjct: 64 IVEFSNHCRNHCHYCGLRTENRQVTRYRLSNEEILNAVDSIAELGLGTVVLQS--GDDFN 121
Query: 181 DGGSLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTP 240
G+ + + EIK+ + ++ + + D + + + +G D + +ET +R
Sbjct: 122 YSGN-RISTLITEIKR-HHNLAITLSLGDRKHQE--LEKWREAGADRYLLKMETFDRALF 177
Query: 241 FVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGL-GETDAQVEQTMKDLREAGVDCVT 299
P+A + + + L K + T S I++ L G TDA + + ++ L E +D +
Sbjct: 178 AQCRPKANFDERIARLNYLKSLGYQ--TGSGIIVDLPGMTDAILARDIQHLSELQLDMLA 235
Query: 300 LGQYM 304
G ++
Sbjct: 236 CGPFI 240
>UniRef50_Q72L21 Cluster: Biotin synthase; n=2; Thermus
thermophilus|Rep: Biotin synthase - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 329
Score = 40.3 bits (90), Expect = 0.077
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 215 GCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIML 274
G + ++G D + HN+ T L P + Y+ L L+ A+E L S ++L
Sbjct: 149 GMAEALKAAGFDYYNHNLNTAPSLYPRIATTHT-YQDRLWTLKRAREAGLKLC--SGVIL 205
Query: 275 GLGETDAQVEQTMKDLREAGVD 296
G+GE +V + LRE GV+
Sbjct: 206 GMGEGPKEVYEMALALRELGVE 227
>UniRef50_Q4AJU3 Cluster: Integrase, catalytic region; n=3;
Chlorobium phaeobacteroides BS1|Rep: Integrase,
catalytic region - Chlorobium phaeobacteroides BS1
Length = 517
Score = 40.3 bits (90), Expect = 0.077
Identities = 23/89 (25%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
Query: 219 RVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGE 278
R+ S G + + +ER+ R P G+R L +L++A+ P+ + ++S L E
Sbjct: 416 RIRSWGAKIGPNTARLLERIMQQRRTPEHGFRSCLGILRLARMFTPERLERAS-RKAL-E 473
Query: 279 TDAQVEQTMKDLREAGVDCVTLGQYMQPT 307
+ +++K + + G+D VTL + +P+
Sbjct: 474 QNMTTYKSIKSMLDNGLDAVTLFEEQEPS 502
>UniRef50_Q04PJ5 Cluster: 2-methylthioadenine synthetase; n=4;
Leptospira|Rep: 2-methylthioadenine synthetase -
Leptospira borgpetersenii serovar Hardjo-bovis (strain
JB197)
Length = 443
Score = 39.5 bits (88), Expect = 0.14
Identities = 46/190 (24%), Positives = 83/190 (43%), Gaps = 27/190 (14%)
Query: 121 TATIMLMGDTCTRGCMFCSVKTSRN-PPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDL 179
T + + D C R C +C + +R ++ + H + GVG IVLT V+
Sbjct: 147 TRAYLKIQDGCNRRCSYCKIPQARGLGVSRKYQDVLDQVHFLQDHGVGEIVLTGVNLGWY 206
Query: 180 PDGGSLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLT 239
DG E K K+ DIL + ++ +R ++ + + + T R T
Sbjct: 207 RDG------ENKKAFNKILADIL---KILEYSRIR--ISSIEPPDVGNELVELMTHPRFT 255
Query: 240 PFVRDP-RAGYRQTLKVL-------------QMAKEINPDLITKSSIMLGL-GETDAQVE 284
PF+ P ++G + LK + ++AKE P+L + I++G GET+
Sbjct: 256 PFLHVPLQSGNAEILKKMKRTYTPETFRKRVEIAKEKIPNLFLGTDIIVGFPGETEEMFL 315
Query: 285 QTMKDLREAG 294
++K +++ G
Sbjct: 316 DSVKMIQDLG 325
>UniRef50_Q97MI6 Cluster: Biotine synthase; n=4; Clostridiales|Rep:
Biotine synthase - Clostridium acetobutylicum
Length = 328
Score = 39.1 bits (87), Expect = 0.18
Identities = 42/199 (21%), Positives = 78/199 (39%), Gaps = 11/199 (5%)
Query: 115 GKHGASTATIMLMGDTCTRGCMFCSVKTSRNP-----PPLDPEEPRNTAHAINHWGVGYI 169
G H + I C+ C FC+ P L+ ++ A +G +
Sbjct: 53 GNHVDLCSVINAKSGNCSEDCAFCAQSAHHKANVSCYPLLNEDKILEMAKQREAYGARHC 112
Query: 170 VLTSVDRDDLPDGGSLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFA 229
+ + G F +K KK+ ++ ++ + +A+ G++ +
Sbjct: 113 DIATSGLGYT--GDEKDFQTILKAFKKMKENTNLKLCACLGTLTEKAMNSLAAVGVERYN 170
Query: 230 HNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKD 289
HN+ET + + GY + +K + AK N + S +++GLGET Q +
Sbjct: 171 HNLETAKSFYKNIVSTH-GYDERIKTINYAK--NAKMEVCSGMIVGLGETMEQRIEHALL 227
Query: 290 LREAGVDCVTLGQYMQPTK 308
LR+ VD V + + P K
Sbjct: 228 LRDLNVDAVPV-NILNPVK 245
>UniRef50_Q9FCC3 Cluster: Biotin synthase; n=9; Actinomycetales|Rep:
Biotin synthase - Streptomyces coelicolor
Length = 407
Score = 37.1 bits (82), Expect = 0.72
Identities = 45/203 (22%), Positives = 76/203 (37%), Gaps = 11/203 (5%)
Query: 124 IMLMGDTCTRGCMFCSVKTSRNPPPLD-----PEEPRNTAHAINHWGVGYIVLTSVDRDD 178
+ L C C +CS + L P++ A A G + L + R
Sbjct: 58 VNLKSGLCPEDCSYCSQRLGSKAEILKYTWLKPDQASAAAAAGVSGGAKRVCLVASGRGP 117
Query: 179 LPDGGSLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERL 238
D ++T+K IK+ N+ + V C + G R+ +G D + HN+ T E
Sbjct: 118 T-DRDVDRVSDTIKAIKEQNESVEV-CACLGLLS-DGQAERLREAGADAYNHNLNTSEST 174
Query: 239 TPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCV 298
+ Y + + A L S ++ G+GE+D + + LRE D V
Sbjct: 175 YGDITTTHT-YADRVDTVNKAHAAG--LSACSGLIAGMGESDEDLVDVVFSLRELDPDSV 231
Query: 299 TLGQYMQPTKKHLKVFEYVTPAR 321
+ + L ++TP R
Sbjct: 232 PVNFLIPMEGTPLAKEWHLTPQR 254
>UniRef50_Q896R1 Cluster: Pyruvate formate-lyase; n=5;
Clostridium|Rep: Pyruvate formate-lyase - Clostridium
tetani
Length = 310
Score = 37.1 bits (82), Expect = 0.72
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 11/110 (10%)
Query: 170 VLTSVDRDDLPDGGSLHFAETVKEIKKLNKDILVEC-LVPDFRAVRGCVARVASSGLDVF 228
+L S + G + E KEI KL KD+++ ++P+F A + +A +A +F
Sbjct: 193 ILNSSKHKEYIGGDNEIILENAKEIVKLVKDVIIRVPVIPEFNADKESIADIA-----MF 247
Query: 229 AHNVETVE--RLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGL 276
A N+ETV+ L P+ + Y+ K M EI I +ML L
Sbjct: 248 AKNLETVKEIHLLPYHKLGVNKYKCVGKEYNMKDEIG---IPSDELMLSL 294
>UniRef50_A7CVG2 Cluster: RNA modification enzyme, MiaB family
precursor; n=1; Opitutaceae bacterium TAV2|Rep: RNA
modification enzyme, MiaB family precursor - Opitutaceae
bacterium TAV2
Length = 562
Score = 37.1 bits (82), Expect = 0.72
Identities = 45/187 (24%), Positives = 75/187 (40%), Gaps = 17/187 (9%)
Query: 131 CTRGCMFCSVKTSRNPPPLDP-EEPRNTAHAINHWGV------GYIVLTSVDRDDLPDGG 183
C C FC V +R P ++ A+ G+ G IV + RD + GG
Sbjct: 254 CNMDCAFCIVPKTRGDERSRPMDDIVAECRALADRGIREITLLGQIVTSYGRRDYVHTGG 313
Query: 184 SLHFAETVKEIKKLNKDILVECLVPDFRAVR----GCVARVASSGLDVFAHNVETVERLT 239
F + ++++ + + P R V+ AR+ V +R+
Sbjct: 314 ITPFVQLIEKVHAIEGIDRIRITSPHPRGVKQDLVDAYARLPKLCEYVHLPMQSGSDRIL 373
Query: 240 PFVRDP--RAGYRQTLKVLQMAKEINPDLITKSSIMLGL-GETDAQVEQTMKDLREAGVD 296
+ P R YRQ ++ L+ A+ PD+ + I++G GETDA+ E T E D
Sbjct: 374 RAMHRPYSRDRYRQIVQSLRAAR---PDMYFSTDIIVGFPGETDAEFEDTRTLFEECNYD 430
Query: 297 CVTLGQY 303
+ +Y
Sbjct: 431 MAYIFKY 437
>UniRef50_A6DP84 Cluster: Biotin synthase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Biotin synthase - Lentisphaera
araneosa HTCC2155
Length = 368
Score = 37.1 bits (82), Expect = 0.72
Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
Query: 219 RVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGE 278
++ +GLD HN+ T E TP + Y L+ L+ +++ L S ++ G+GE
Sbjct: 158 KLKDAGLDRLNHNLNTSESHTPEIVTTHT-YEDRLETLRNSRKAG--LENCSGMIAGMGE 214
Query: 279 TDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPAR 321
+D V ++R GV + + + + F+ + P R
Sbjct: 215 SDNDVVDVALEVRRLGVPSIPVNFLVPVEGNRIFDFDQLDPIR 257
>UniRef50_A0LJA8 Cluster: Biotin synthase; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: Biotin synthase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 326
Score = 37.1 bits (82), Expect = 0.72
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 212 AVRGCVAR-----VASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDL 266
A GC+ R + +G+ F HN+ET E P + GY Q L ++ +E+ ++
Sbjct: 143 ASMGCLDRSRLQLLKEAGVSRFHHNLETAESYFPEICSTH-GYAQRLDTVRAVREVGLEV 201
Query: 267 ITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTL 300
+LGLGE+ Q + L VDC+ L
Sbjct: 202 CCGG--ILGLGESLEQRVEFAALLAREEVDCIPL 233
>UniRef50_Q1PUX5 Cluster: Similar to biotin synthase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Similar to
biotin synthase - Candidatus Kuenenia stuttgartiensis
Length = 454
Score = 36.7 bits (81), Expect = 0.95
Identities = 44/189 (23%), Positives = 86/189 (45%), Gaps = 14/189 (7%)
Query: 124 IMLMGDTCTRGCMFCSV-KTSRNPP--PLDPEEPRNTAH-AINHWGVGYIVLTSVDRDDL 179
I+ + C R C++C + + S+N + P+E N+ + A+NH G IVL S DDL
Sbjct: 166 IVEFSNYCVRNCLYCGLRRDSKNVRRYRMTPDEIVNSVYDAVNHRGYKLIVLQS--GDDL 223
Query: 180 PDGGSLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLDVFAHNVETVERLT 239
+ + +++IK+ K + + V + R G ++ +G + ET +
Sbjct: 224 SYTNEI-LSGIIRKIKEKCK-VFIFMSVGE-RTSEG-YRKMKDAGANGVLFRFETSNKAL 279
Query: 240 PFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGL-GETDAQVEQTMKDLREAGVDCV 298
P + + +L K++ + T ++GL G+T + + ++ G + V
Sbjct: 280 YHSLHPGQSFDDRIALLMEMKKMGYFIAT--GFLIGLPGQTVEDIADDIITIKSIGANMV 337
Query: 299 TLGQYMQPT 307
T G ++ PT
Sbjct: 338 TAGPFI-PT 345
>UniRef50_A1ID94 Cluster: Biotin synthase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: Biotin synthase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 334
Score = 36.7 bits (81), Expect = 0.95
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Query: 215 GCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIML 274
G +A + +G+ + HN+E+ E L V Y + ++ ++ AK + +
Sbjct: 157 GQLAMLRDAGVTRYHHNLESAESLFANVCTTHT-YEERVQTVKAAKAAGLSVCCGG--IF 213
Query: 275 GLGETDAQVEQTMKDLREAGVDCVTLGQYMQPTK 308
GLGETD QV + LR+ VD V + ++ P K
Sbjct: 214 GLGETDDQVAELAFALRDLDVDSVPV-NFLVPIK 246
>UniRef50_A1VB97 Cluster: Biotin synthase; n=4;
Deltaproteobacteria|Rep: Biotin synthase - Desulfovibrio
vulgaris subsp. vulgaris (strain DP4)
Length = 361
Score = 36.3 bits (80), Expect = 1.3
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Query: 218 ARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLG 277
A + +G + HN+ET P + A Y + ++ A+ L T S + G+G
Sbjct: 192 ACLKEAGFSSYHHNLETSRSFFPAICSTHA-YDDDIATVRAARAAG--LRTCSGGIFGMG 248
Query: 278 ETDAQVEQTMKDLREAGVDCV 298
ETDAQ + LRE VD +
Sbjct: 249 ETDAQRIELSATLRELDVDSI 269
>UniRef50_O26568 Cluster: Sensory transduction histidine kinase;
n=1; Methanothermobacter thermautotrophicus str. Delta
H|Rep: Sensory transduction histidine kinase -
Methanobacterium thermoautotrophicum
Length = 554
Score = 35.1 bits (77), Expect = 2.9
Identities = 18/60 (30%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 278 ETDAQVEQTMKDLREAGVDCVTLGQYMQPTKKHLKVFEYVTPARFQQWEARGRQLGFLYV 337
+T+A V ++ L AGV+ VT+ ++ + V Y TPAR +W + ++ F+Y+
Sbjct: 9 DTEADVSDLLEKLSSAGVE-VTVADKIERAAEADTVLIYTTPARVSRWASCDIRVPFMYL 67
>UniRef50_P73127 Cluster: UPF0004 protein sll0996; n=37;
Cyanobacteria|Rep: UPF0004 protein sll0996 -
Synechocystis sp. (strain PCC 6803)
Length = 451
Score = 35.1 bits (77), Expect = 2.9
Identities = 15/52 (28%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 253 LKVLQMAKEINPDLITKSSIMLGL-GETDAQVEQTMKDLREAGVDCVTLGQY 303
L++++ + PD + +++G GET+AQ E T+ + E G D + Y
Sbjct: 292 LQIIEKIRRYMPDAAISADVIVGFPGETEAQFENTLNLIEEVGFDLLNTAAY 343
>UniRef50_A3TFV2 Cluster: Putative uncharacterized protein; n=1;
Janibacter sp. HTCC2649|Rep: Putative uncharacterized
protein - Janibacter sp. HTCC2649
Length = 173
Score = 34.7 bits (76), Expect = 3.8
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 132 TRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLHFAET 190
T G +T P L E N H WG G+ +T V DL +GG+ HFA+T
Sbjct: 21 TEGSEMVITRTFPAPADLVFEAMTNPEHIRKWWGAGHGTMT-VCEVDLREGGAWHFAQT 78
>UniRef50_A5K8V8 Cluster: Kinesin motor domain containing protein;
n=1; Plasmodium vivax|Rep: Kinesin motor domain
containing protein - Plasmodium vivax
Length = 1489
Score = 34.7 bits (76), Expect = 3.8
Identities = 18/50 (36%), Positives = 30/50 (60%)
Query: 13 KHLDFPRYKHSNKLDAIREKLKEGPNLTDFISEDRPKNWDEYQGKLKREK 62
K+LDF + NK+D I+E+L +G T+ ++E K +DE + + EK
Sbjct: 643 KYLDFFIESYKNKIDIIKEQLNKGGAATNDVNECILKTFDELKLLTEEEK 692
>UniRef50_UPI0000E488B2 Cluster: PREDICTED: similar to cell-cycle
and apoptosis regulatory protein 1; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
cell-cycle and apoptosis regulatory protein 1 -
Strongylocentrotus purpuratus
Length = 1183
Score = 34.3 bits (75), Expect = 5.1
Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 16 DFPRYKHSNKLDAI--REKLKEGPNLTDFISEDRPKNWDEYQGKLKREKGESERLRLPPW 73
D R SNKL A+ R+K E P T F+ + P E + E+ E + + P
Sbjct: 573 DLYRKTLSNKLAAVDSRDKKTEDPTPTQFLESEEPAAVKEEE----EEEVEEQEHQTPTN 628
Query: 74 LKTTIPTGSKFNEIKQQL 91
K P K NE++Q+L
Sbjct: 629 WKELDPKNMKVNELRQEL 646
>UniRef50_Q2LY09 Cluster: Biotin synthase; n=1; Syntrophus
aciditrophicus SB|Rep: Biotin synthase - Syntrophus
aciditrophicus (strain SB)
Length = 325
Score = 34.3 bits (75), Expect = 5.1
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 219 RVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGE 278
R+ + G+ V+ HN+ET P + Y + ++ L +A++ L S + GLGE
Sbjct: 159 RLKAGGVSVYHHNLETARSFFPQICTTH-DYEEDIETLLIARKAGLRLC--SGGIFGLGE 215
Query: 279 TDAQVEQTMKDLREAGVDCVTLGQYMQP 306
+ Q + LRE VD + + ++ P
Sbjct: 216 SWEQRVEMAFTLRELDVDSIPI-NFLNP 242
>UniRef50_Q1NNS2 Cluster: Biotin synthase; n=3; delta
proteobacterium MLMS-1|Rep: Biotin synthase - delta
proteobacterium MLMS-1
Length = 318
Score = 34.3 bits (75), Expect = 5.1
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 214 RGCVARVASSGLDVFAHNVETVERLTPFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIM 273
R + R ++G+ + HN+ET ER P V + + + L + A++ ++ +
Sbjct: 143 RATLERFKAAGMSRYHHNLETSERFFPQVTTTHS-FAERLATIAAARDAGLEICAGG--I 199
Query: 274 LGLGETDAQVEQTMKDLREAGVDCVTL 300
GLGE D L E VD V L
Sbjct: 200 FGLGEDDDDRLSLAATLAELRVDSVPL 226
>UniRef50_Q1IV15 Cluster: Response regulator receiver protein; n=1;
Acidobacteria bacterium Ellin345|Rep: Response regulator
receiver protein - Acidobacteria bacterium (strain
Ellin345)
Length = 995
Score = 34.3 bits (75), Expect = 5.1
Identities = 27/113 (23%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
Query: 183 GSLHFAETVKEIKKLNKDILVECLVPDFRAVRGCVARVASSGLD---VFAHNVETVERLT 239
G ++ A+ +EI+K D+ V L D+R V+ +AR + +D ++ N + +
Sbjct: 97 GEMNAAQLAREIRKSGSDVPVLVLAYDYREVKNFIARNPVTDIDRIFLWQGNARVLVAMV 156
Query: 240 PFVRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLRE 292
++ D R T V + D I S +L + T+ + Q+ + +RE
Sbjct: 157 KYIEDKRNALHDTKTVGVPVLLVVEDNIRYYSSVLPVIYTEL-ITQSKRVIRE 208
>UniRef50_A1KQR7 Cluster: RhiB protein; n=1; Burkholderia
rhizoxina|Rep: RhiB protein - Burkholderia rhizoxina
Length = 6722
Score = 34.3 bits (75), Expect = 5.1
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 19 RYKHSNKLDAIREKLKEGPNLTDFISEDRPKNWDEYQGKLKREKG 63
RY HS+ + A+ ++LK G N D + DR +W +Y + +KG
Sbjct: 3761 RYAHSDNVQALWQRLKNGENCIDEVPADR-WDWRQYFDQTPGKKG 3804
>UniRef50_A2SS95 Cluster: Radical SAM domain protein; n=1;
Methanocorpusculum labreanum Z|Rep: Radical SAM domain
protein - Methanocorpusculum labreanum (strain ATCC
43576 / DSM 4855 / Z)
Length = 348
Score = 33.9 bits (74), Expect = 6.7
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 114 GGKHGASTATIMLMGDTCTRGCMFCSVKTSRNPPPLDPEEPRNTAHAINHWG-VGYIVL- 171
G H + I+L G TC+ C +C V T R P+E + ++ G VG ++L
Sbjct: 27 GKTHQCTPMRILLEG-TCSFDCAYCQVCTKRTGIHFTPDELAHGFLELHRQGKVGGLLLS 85
Query: 172 TSVDRDDLPDGGSLHFAETVKEIK 195
T + R D+ D G ET K I+
Sbjct: 86 TGIPRGDV-DLGMEKLTETAKIIR 108
>UniRef50_Q47VK0 Cluster: Chaperone surA precursor; n=2;
Alteromonadales|Rep: Chaperone surA precursor -
Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
(Vibriopsychroerythus)
Length = 433
Score = 33.9 bits (74), Expect = 6.7
Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 251 QTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYMQ 305
+ L++ M K IN L+++ +G+ +DAQ++QT+ ++ A D +TL Q+ Q
Sbjct: 68 KALRIQVMDKLINDSLLSQMGQRMGIQISDAQLDQTLNNM--AREDKLTLAQFRQ 120
>UniRef50_Q74CT7 Cluster: Biotin synthetase; n=7;
Desulfuromonadales|Rep: Biotin synthetase - Geobacter
sulfurreducens
Length = 329
Score = 33.5 bits (73), Expect = 8.9
Identities = 45/182 (24%), Positives = 70/182 (38%), Gaps = 14/182 (7%)
Query: 131 CTRGCMFC--SVKTSRNPP--PLDPEEPRNTAHAINHWGVGYIVLTSVDRDDLPDGGSLH 186
C C FC S + N P PL EE + TA A G G V G
Sbjct: 66 CPENCAFCAQSAHHATNAPVYPLVDEE-QITACAREAAGAGSHCFGIVTSGSAISRGE-E 123
Query: 187 FAETVKEIKKLNKDILVE--CLVPDFRAVRGCVARVASSGLDVFAHNVETVERLTPFVRD 244
+ ++++ ++ +E C + R A G + HN+ET P V
Sbjct: 124 LDRICRALRRIRRETAIEPSCSLGVIDYETALALREA--GAVTYHHNLETARSFFPNVCT 181
Query: 245 PRAGYRQTLKVLQMAKEINPDLITKSSIMLGLGETDAQVEQTMKDLREAGVDCVTLGQYM 304
Y + ++ +++AK + + GLGET Q + LRE VD + L ++
Sbjct: 182 TH-DYEEDVETVRVAKRAGLKVCCGG--IFGLGETPEQRVEMALTLRELDVDSIPL-NFL 237
Query: 305 QP 306
P
Sbjct: 238 NP 239
>UniRef50_A6SXU1 Cluster: MiaB-like tRNA modifying enzyme; n=19;
Proteobacteria|Rep: MiaB-like tRNA modifying enzyme -
Janthinobacterium sp. (strain Marseille) (Minibacterium
massiliensis)
Length = 453
Score = 33.5 bits (73), Expect = 8.9
Identities = 18/56 (32%), Positives = 34/56 (60%), Gaps = 2/56 (3%)
Query: 242 VRDPRAGYRQTLKVLQMAKEINPDLITKSSIMLGL-GETDAQVEQTMKDLREAGVD 296
++ P +G + ++ +Q + + PDL +S+ + G GETDA+ E + L+EA +D
Sbjct: 284 MKRPASG-EKNIERIQAWRAMCPDLTIRSTFIAGFPGETDAEFEYLLDFLKEAEID 338
>UniRef50_A4M7N1 Cluster: MiaB-like tRNA modifying enzyme YliG; n=2;
Thermotogaceae|Rep: MiaB-like tRNA modifying enzyme YliG
- Petrotoga mobilis SJ95
Length = 435
Score = 33.5 bits (73), Expect = 8.9
Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 1/50 (2%)
Query: 127 MGDTCTRGCMFCSVKTSR-NPPPLDPEEPRNTAHAINHWGVGYIVLTSVD 175
+GD C+R C FCS+ T + P EE + GV I+L S D
Sbjct: 146 IGDGCSRNCAFCSIPTFKGKPKSRSIEEINEEVEFLVSKGVKEIILVSQD 195
>UniRef50_Q5C3Q8 Cluster: SJCHGC02377 protein; n=2; Schistosoma
japonicum|Rep: SJCHGC02377 protein - Schistosoma
japonicum (Blood fluke)
Length = 426
Score = 33.5 bits (73), Expect = 8.9
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 72 PWLKTTIPTGSKFNEIKQQLRSLKLSTVCEEARCPNIGECWS 113
P++ IP+ SKF+ + R + LS C E++ PN E WS
Sbjct: 31 PFVTPVIPSHSKFDFLSAS-RQIHLSGYCLESKIPNFFELWS 71
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.319 0.135 0.408
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 411,746,292
Number of Sequences: 1657284
Number of extensions: 17081972
Number of successful extensions: 46145
Number of sequences better than 10.0: 72
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 45993
Number of HSP's gapped (non-prelim): 76
length of query: 366
length of database: 575,637,011
effective HSP length: 102
effective length of query: 264
effective length of database: 406,594,043
effective search space: 107340827352
effective search space used: 107340827352
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 73 (33.5 bits)
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