BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001085-TA|BGIBMGA001085-PA|IPR004729|Transient receptor potential channel, IPR002110|Ankyrin, IPR013555|Transient receptor ion channel II, IPR005821|Ion transport, IPR001086|Prephenate dehydratase (1024 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI00015B586A Cluster: PREDICTED: similar to TRPgamma c... 1227 0.0 UniRef50_Q9VJJ7 Cluster: Transient receptor potential-gamma prot... 1222 0.0 UniRef50_P48994 Cluster: Transient-receptor-potential-like prote... 809 0.0 UniRef50_P19334 Cluster: Transient receptor potential protein; n... 790 0.0 UniRef50_Q9UBN4 Cluster: Short transient receptor potential chan... 691 0.0 UniRef50_Q8I6Y9 Cluster: Trp (Transient receptor potential) chan... 664 0.0 UniRef50_Q4RRG2 Cluster: Chromosome 16 SCAF15002, whole genome s... 595 e-168 UniRef50_Q8IS32 Cluster: Transient receptor potential ion channe... 506 e-141 UniRef50_P48995 Cluster: Short transient receptor potential chan... 491 e-137 UniRef50_P34586 Cluster: Transient-receptor-potential-like prote... 449 e-124 UniRef50_Q96P03 Cluster: Transient receptor potential channel 4 ... 446 e-123 UniRef50_UPI000069F43F Cluster: Short transient receptor potenti... 445 e-123 UniRef50_Q9Y210 Cluster: Short transient receptor potential chan... 438 e-121 UniRef50_UPI0000E494DE Cluster: PREDICTED: similar to transient ... 349 3e-94 UniRef50_UPI000058480E Cluster: PREDICTED: similar to putative c... 349 3e-94 UniRef50_Q9R244 Cluster: Short transient receptor potential chan... 339 2e-91 UniRef50_Q4VDB0 Cluster: Transient receptor potential channel C2... 338 3e-91 UniRef50_A7RSZ7 Cluster: Predicted protein; n=1; Nematostella ve... 275 3e-72 UniRef50_UPI0000E4A5BA Cluster: PREDICTED: similar to transient ... 261 6e-68 UniRef50_Q179M4 Cluster: Transient receptor potential channel 4,... 256 3e-66 UniRef50_UPI0000D55FE0 Cluster: PREDICTED: similar to transient ... 251 6e-65 UniRef50_A7RJX1 Cluster: Predicted protein; n=1; Nematostella ve... 250 2e-64 UniRef50_Q4S8W5 Cluster: Chromosome 7 SCAF14703, whole genome sh... 230 1e-58 UniRef50_Q70T25 Cluster: Transient receptor potential channel 7;... 215 4e-54 UniRef50_UPI0000E4A874 Cluster: PREDICTED: hypothetical protein,... 198 8e-49 UniRef50_UPI0000E46FC6 Cluster: PREDICTED: similar to transient ... 192 3e-47 UniRef50_UPI0000E46001 Cluster: PREDICTED: similar to transient ... 190 2e-46 UniRef50_Q6L6S5 Cluster: Transient receptor potential cation cha... 178 5e-43 UniRef50_A7RH68 Cluster: Predicted protein; n=1; Nematostella ve... 152 5e-35 UniRef50_UPI0000F2E5D0 Cluster: PREDICTED: similar to capacitati... 111 9e-23 UniRef50_UPI0000E46FC8 Cluster: PREDICTED: hypothetical protein;... 104 1e-20 UniRef50_UPI0000E46CF0 Cluster: PREDICTED: hypothetical protein;... 95 7e-18 UniRef50_A7SYW3 Cluster: Predicted protein; n=1; Nematostella ve... 95 9e-18 UniRef50_UPI0000F20B7A Cluster: PREDICTED: similar to CG5284-PA,... 89 6e-16 UniRef50_Q21070 Cluster: Putative uncharacterized protein spe-41... 88 1e-15 UniRef50_A7SYK9 Cluster: Predicted protein; n=3; Nematostella ve... 84 2e-14 UniRef50_UPI0000E46FC7 Cluster: PREDICTED: similar to trpc3; n=1... 75 8e-12 UniRef50_Q9TXE9 Cluster: TRP PROTEIN=140 kDa integral RHABDOMERA... 75 1e-11 UniRef50_UPI0000E4A58D Cluster: PREDICTED: similar to transient ... 74 2e-11 UniRef50_Q7T1G6 Cluster: Ion channel NompC; n=4; Danio rerio|Rep... 71 1e-10 UniRef50_Q5C082 Cluster: SJCHGC03783 protein; n=1; Schistosoma j... 69 5e-10 UniRef50_Q5C0X3 Cluster: SJCHGC09110 protein; n=1; Schistosoma j... 62 8e-08 UniRef50_Q0Z852 Cluster: TRP-like ion channel; n=2; Chlamydomona... 60 2e-07 UniRef50_A5A3A6 Cluster: TRPC1 splice variant; n=7; Euteleostomi... 58 1e-06 UniRef50_UPI0000F1ED97 Cluster: PREDICTED: similar to putative T... 58 2e-06 UniRef50_A7RZ54 Cluster: Predicted protein; n=1; Nematostella ve... 56 7e-06 UniRef50_Q4RQP9 Cluster: Chromosome 2 SCAF15004, whole genome sh... 53 3e-05 UniRef50_O94759 Cluster: Transient receptor potential cation cha... 52 1e-04 UniRef50_A7T1N0 Cluster: Predicted protein; n=1; Nematostella ve... 50 4e-04 UniRef50_A7SD04 Cluster: Predicted protein; n=1; Nematostella ve... 50 4e-04 UniRef50_Q7Z2W7 Cluster: Transient receptor potential cation cha... 49 7e-04 UniRef50_UPI000065CCB2 Cluster: Transient receptor potential cat... 48 0.001 UniRef50_Q4A520 Cluster: Putative transient receptor potential c... 48 0.001 UniRef50_Q4SEW5 Cluster: Chromosome undetermined SCAF14611, whol... 48 0.002 UniRef50_Q7Z4N2 Cluster: Melastatin 1; n=43; Euteleostomi|Rep: M... 48 0.002 UniRef50_A7RLT7 Cluster: Predicted protein; n=1; Nematostella ve... 47 0.002 UniRef50_UPI0000F1F31D Cluster: PREDICTED: hypothetical protein;... 46 0.004 UniRef50_UPI00003BFA30 Cluster: PREDICTED: similar to no mechano... 46 0.004 UniRef50_Q7S8B0 Cluster: Predicted protein; n=1; Neurospora cras... 46 0.005 UniRef50_Q9P0L9 Cluster: Polycystic kidney disease 2-like 1 prot... 46 0.005 UniRef50_Q7S9R4 Cluster: Predicted protein; n=5; Pezizomycotina|... 44 0.028 UniRef50_Q0UIA7 Cluster: Putative uncharacterized protein; n=1; ... 43 0.037 UniRef50_Q3ALE0 Cluster: Ankyrin; n=1; Synechococcus sp. CC9605|... 43 0.049 UniRef50_A1CU15 Cluster: Cation channel family transporter, puta... 43 0.049 UniRef50_Q8NLI7 Cluster: Uncharacterized membrane proteins; n=3;... 41 0.15 UniRef50_A7SVF4 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.20 UniRef50_Q2UHE0 Cluster: Predicted protein; n=1; Aspergillus ory... 41 0.20 UniRef50_A6R3T2 Cluster: Predicted protein; n=1; Ajellomyces cap... 41 0.20 UniRef50_UPI0000D569A5 Cluster: PREDICTED: similar to CG30078-PA... 39 0.80 UniRef50_UPI0000D55731 Cluster: PREDICTED: similar to polycystic... 39 0.80 UniRef50_UPI0000E4996E Cluster: PREDICTED: similar to transient ... 38 1.1 UniRef50_A6RWT7 Cluster: Putative uncharacterized protein; n=1; ... 38 1.1 UniRef50_Q0E967 Cluster: CG34123-PD, isoform D; n=12; Coelomata|... 38 1.4 UniRef50_A0BSQ9 Cluster: Chromosome undetermined scaffold_125, w... 38 1.4 UniRef50_Q4SM12 Cluster: Chromosome 13 SCAF14555, whole genome s... 38 1.8 UniRef50_Q4RVK8 Cluster: Chromosome 15 SCAF14992, whole genome s... 38 1.8 UniRef50_Q2H0G7 Cluster: Putative uncharacterized protein; n=1; ... 38 1.8 UniRef50_Q2GZU3 Cluster: Putative uncharacterized protein; n=1; ... 38 1.8 UniRef50_A2QRW5 Cluster: Remark: TRP2; n=1; Aspergillus niger|Re... 38 1.8 UniRef50_UPI0000DB7C9A Cluster: PREDICTED: similar to trp CG5996... 37 2.4 UniRef50_A4S1E9 Cluster: Predicted protein; n=1; Ostreococcus lu... 37 3.2 UniRef50_Q9U1S7 Cluster: Putative uncharacterized protein pkd-2;... 37 3.2 UniRef50_Q9NZQ8 Cluster: MTR1; n=31; Euteleostomi|Rep: MTR1 - Ho... 37 3.2 UniRef50_A4RKC7 Cluster: Putative uncharacterized protein; n=1; ... 37 3.2 UniRef50_UPI00015B5D3F Cluster: PREDICTED: similar to CG34123-PD... 36 4.3 UniRef50_UPI00001C1FBC Cluster: PREDICTED: hypothetical protein;... 36 4.3 UniRef50_A6S4E5 Cluster: Putative uncharacterized protein; n=1; ... 36 4.3 UniRef50_Q96QT4 Cluster: Transient receptor potential cation cha... 36 4.3 UniRef50_Q9NZM6 Cluster: Polycystic kidney disease 2-like 2 prot... 36 4.3 UniRef50_Q574D7 Cluster: Ankyrin G217; n=8; Euteleostomi|Rep: An... 36 5.6 UniRef50_Q12955 Cluster: Ankyrin-3; n=78; root|Rep: Ankyrin-3 - ... 36 5.6 UniRef50_Q8DA59 Cluster: Multidrug resistance protein D; n=39; G... 36 7.5 UniRef50_A7LAU2 Cluster: Arp; n=4; Brachyspira|Rep: Arp - Trepon... 36 7.5 UniRef50_A2QGH1 Cluster: Function: ankyrins link the spectrin-ba... 36 7.5 UniRef50_A1C5N6 Cluster: Ankyrin repeat protein; n=1; Aspergillu... 36 7.5 UniRef50_Q9HCD6 Cluster: TPR repeat, ankyrin repeat and coiled-c... 35 9.9 UniRef50_Q0U645 Cluster: Putative uncharacterized protein; n=1; ... 35 9.9 >UniRef50_UPI00015B586A Cluster: PREDICTED: similar to TRPgamma cation channel; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to TRPgamma cation channel - Nasonia vitripennis Length = 1313 Score = 1227 bits (3040), Expect = 0.0 Identities = 623/957 (65%), Positives = 725/957 (75%), Gaps = 63/957 (6%) Query: 31 EPRPLDSKVKRHSIHGMTEEENVVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRAR 90 E +D KVKRHSIHGM E+ENV+RPHQEM LS +++K+LL VERGDVAG R++L + Sbjct: 131 EKPEIDKKVKRHSIHGMMEDENVIRPHQEMIRLSTDDRKFLLAVERGDVAGVRKILTENK 190 Query: 91 DTGHINVDCVDPLGRSALLMAIDXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALL 150 + IN++CVDPLGRSALLMAID + V+T+DALLHAISEEFVEAVE LL Sbjct: 191 EK--ININCVDPLGRSALLMAIDNENLEMVELLINYKVDTKDALLHAISEEFVEAVERLL 248 Query: 151 DHEERTRKPGEPNSWEALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDV 210 DHEE + GEP+SWEALPP+TATFT DITPLIL+AHRD++EI K+LLDRG+ LP PHDV Sbjct: 249 DHEEEFHRNGEPHSWEALPPDTATFTPDITPLILSAHRDNFEITKILLDRGSTLPMPHDV 308 Query: 211 RCGCDDCVRSRREDSLRHSRSRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALE 270 RCGCD+CV SR EDSLRHSRSRINAYR KDPILTAFELSWELRRLS LE Sbjct: 309 RCGCDECVTSRLEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLE 368 Query: 271 HEFKTEYQELRVQCQEFATALLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSR 330 HEFK EYQELR QCQ+FATALLDHTR+S EL++LLNH+ P P E G ERM L+R Sbjct: 369 HEFKCEYQELRRQCQDFATALLDHTRSSYELEVLLNHD----PTGPAFEHG--ERMHLNR 422 Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYI 390 LKLA+KLRQKKFVAHPNVQQLLASIWYE +PGFRRKNM+LQA E+VRIG +FP +S+AYI Sbjct: 423 LKLAVKLRQKKFVAHPNVQQLLASIWYEGLPGFRRKNMVLQALEIVRIGILFPFFSVAYI 482 Query: 391 AAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLW---DVS-HDEPL 446 APHS +G+T+RKPFIKF+CHSASYF FLF+LILASQRIE+ G +W D+S H+ Sbjct: 483 IAPHSVIGQTMRKPFIKFICHSASYFTFLFMLILASQRIESVIG--VWTGRDISEHEIEP 540 Query: 447 SRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALR 506 ++RG+ P++VEW ILAWVSGLIWSEVKQLWD+GL EYV+DMWNVIDFVTNSLYVATVALR Sbjct: 541 TKRGAAPTLVEWFILAWVSGLIWSEVKQLWDVGLEEYVNDMWNVIDFVTNSLYVATVALR 600 Query: 507 IVSHYQVRRE-MAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLG 565 +V++Y+V++E + + RE+WD WDPML+SEGLFSAANIFSSLKLVYIFSVNPHLG Sbjct: 601 VVAYYRVQKENEGSDIIVDLQREQWDTWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLG 660 Query: 566 PLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRC-TVGTALTPNGTL- 623 PLQVSLSRMV+DI+KFF L +LV+FAFSCGLNQLLWYYADMEKKRC T L PN + Sbjct: 661 PLQVSLSRMVMDIMKFFFLYVLVLFAFSCGLNQLLWYYADMEKKRCPTAMPHLPPNANIT 720 Query: 624 PDPDACVVWRR---LFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXX 680 DP+AC+VWRR LFET QTLFWA FGLVDL+SFELDGIK+FTRFWGMLMFGTY Sbjct: 721 QDPNACIVWRRFANLFETTQTLFWAVFGLVDLESFELDGIKVFTRFWGMLMFGTYSVINI 780 Query: 681 XXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYA 740 HSYQLISERAD+EWKFARSKLWISYFEEGGT PPPFN++P+PKS+ Y Sbjct: 781 VVLLNLLIAMMNHSYQLISERADIEWKFARSKLWISYFEEGGTVPPPFNIIPTPKSIWYI 840 Query: 741 WRWLQRRLCGHAR-AKREHMRTI---------RAIMRNLVRRYVTVQQRRAESGGVTEDD 790 +W+ R+LCGH+R AK+EHMRTI RAIM+NLVRRYVTV+QR+ E+ GVTEDD Sbjct: 841 TQWIYRKLCGHSRAAKKEHMRTIRASERDDRYRAIMKNLVRRYVTVEQRKTENEGVTEDD 900 Query: 791 VNEIKQDVSAFRCELVEILRNSGMNTS-TANAGAPEVMMLRAGGGGGKKNRQKERRLMKG 849 VNEIKQD+SAFRCEL+ IL+ SGM T T+ G G GGKKNRQKERRLMKG Sbjct: 901 VNEIKQDISAFRCELINILQKSGMATEHTSGTGT---------GVGGKKNRQKERRLMKG 951 Query: 850 FN-----IAP----GGSLAPVDEFMSPVSWLQHDHG--VPHYSLSTLLG--------PRL 890 + P G L PV E + + QH PH S+ L P+ Sbjct: 952 LGGLDGPLGPQPSGSGPLPPVAEATASLRDHQHQTSGHHPHDIFSSTLSGIFRPGTTPKR 1011 Query: 891 RASQSSLSDGPGAG----MSASRRKPQHKRRWGTIIDAARAARVSRLIGRSRSEDSV 943 +S + PG S R KRRWGT+I+AA+A RVSRLIGRSRS+DSV Sbjct: 1012 NPHHTSTNSVPGLASCQRQSRDSRGSSRKRRWGTLIEAAKAGRVSRLIGRSRSQDSV 1068 >UniRef50_Q9VJJ7 Cluster: Transient receptor potential-gamma protein; n=15; Coelomata|Rep: Transient receptor potential-gamma protein - Drosophila melanogaster (Fruit fly) Length = 1128 Score = 1222 bits (3027), Expect = 0.0 Identities = 627/964 (65%), Positives = 732/964 (75%), Gaps = 80/964 (8%) Query: 47 MTEEENVVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRS 106 M EEEN +RPHQE+ L+LEEKK+LL VERGD+AGTRR+LQ+A+DT +INV+CVDPLGR+ Sbjct: 1 MMEEENTIRPHQEIRQLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRT 60 Query: 107 ALLMAIDXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWE 166 ALLMAID + V+T+DALLH+ISEEFVEAVE LLDHE T +SWE Sbjct: 61 ALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWE 120 Query: 167 ALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSL 226 + +T+TFT DITPLILAAHRD+YEIIK+LLDRGA LP PHDVRCGCD+CV+SR+EDSL Sbjct: 121 SASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSL 180 Query: 227 RHSRSRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQE 286 RHSRSRINAYR KDPILTAFELSWELRRLS LEHEFK EYQELR QCQ+ Sbjct: 181 RHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQD 240 Query: 287 FATALLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHP 346 FATALLDHTRTS+EL+ILLNH+ P P+ E G ERM L+RLKLAIKLRQKKFVAH Sbjct: 241 FATALLDHTRTSHELEILLNHD----PTGPVYEHG--ERMHLNRLKLAIKLRQKKFVAHS 294 Query: 347 NVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFI 406 NVQQLLASIWYE +PGFRRKNM LQA +++RIG MFP++SLAYI AP+S++G+T+RKPFI Sbjct: 295 NVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFI 354 Query: 407 KFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSH------DEPLSRRGSMPSIVEWLI 460 KF+CHSASYF FLFLL+LASQRIET GG + S +E ++RG+ P+ +EWLI Sbjct: 355 KFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEELPTKRGAKPTFIEWLI 414 Query: 461 LAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMG 520 LAWVSGLIWSEVKQLWD+GL+EY++DMWNVIDFVTNSLYVATVALR+VS +QV++EM Sbjct: 415 LAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMIYN 474 Query: 521 LQ-WNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDIL 579 + PRE+WDAWDPML+SEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMV+DI+ Sbjct: 475 SHATDLPRERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIM 534 Query: 580 KFFVLDILVIFAFSCGLNQLLWYYADMEKKRC----TVGTALTPNGTLPDPDACVVWRR- 634 KFF L +LV+FAF GLNQLLWYYAD+EKKRC + L NGT DP+AC+VWRR Sbjct: 535 KFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGT-NDPNACIVWRRF 593 Query: 635 --LFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXX 692 LFET QTLFWA FGL+DLDSFELDGIKIFTRFWGMLMFGTY Sbjct: 594 SNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMN 653 Query: 693 HSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GH 751 HSYQLISERADVEWKFARSKLWISYFEEGGT PPPFN++P+PKS+ YA +W++R C G Sbjct: 654 HSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGS 713 Query: 752 ARAKREHMRTIR--------------AIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQD 797 + A+REH++TIR IMRNLVRRYVTV+QR+AES GVTEDDVNEIKQD Sbjct: 714 SAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNEIKQD 773 Query: 798 VSAFRCELVEILRNSGMNTSTANAGAPEVMMLRAGGGGGKKNRQKERRLMKGFNIAP--- 854 +SAFRCELVEIL+NSGM+T+ AG + GGGGGKKNRQKERRLMKGFNIAP Sbjct: 774 ISAFRCELVEILKNSGMDTN-VTAG-------QGGGGGGKKNRQKERRLMKGFNIAPPGS 825 Query: 855 GGSLAPVDEFMSPVSWLQHDHGVPHYSLSTLLGPRL--RASQSSLSDG------------ 900 GSLAPV EF + + + H + +LSTL P + QS G Sbjct: 826 TGSLAPVAEFSTSLDNYDNQHEILSSTLSTLFTPNFMHKRQQSQAGSGGGGSESPTTPTA 885 Query: 901 ----PGAGMSASRR---------KPQHKR------RWGTIIDAARAARVSRLIGRSRSED 941 GA M+AS + KP +KR RWGT+I+AA+ VS+++GRS+SED Sbjct: 886 PQGTQGAAMTASSQVTKYNKSALKPYNKRIAGHKKRWGTLIEAAKVGNVSKMLGRSKSED 945 Query: 942 SVCD 945 SVC+ Sbjct: 946 SVCN 949 >UniRef50_P48994 Cluster: Transient-receptor-potential-like protein; n=5; Endopterygota|Rep: Transient-receptor-potential-like protein - Drosophila melanogaster (Fruit fly) Length = 1124 Score = 809 bits (2001), Expect = 0.0 Identities = 404/817 (49%), Positives = 545/817 (66%), Gaps = 33/817 (4%) Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122 L LEEKK+LL VERGD+ RR+LQ+A HIN++C+DPLGR AL +AID Sbjct: 38 LLLEEKKFLLAVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVEL 97 Query: 123 XXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPL 182 GVET+DALLHAI+ EFVEAVE LL+HEE K GEP SW+ + TA F DITPL Sbjct: 98 LVVMGVETKDALLHAINAEFVEAVELLLEHEELIYKEGEPYSWQKVDINTAMFAPDITPL 157 Query: 183 ILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXX 242 +LAAH++++EI+++LLDRGA +P PHD+RCGC++CVR EDSLRHS SR+N YR Sbjct: 158 MLAAHKNNFEILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSP 217 Query: 243 XXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQ 302 DPI+TAF+LSWELR L+ E E K+EY +LR QCQ+FA LLD TRTSNEL Sbjct: 218 SLICLTSNDPIITAFQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELA 277 Query: 303 ILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPG 362 I+LN++ PQ EPG +RM L+RL AI +QKKFVAH N+QQLL+SIWY+ +PG Sbjct: 278 IILNYD----PQMSSYEPG--DRMSLTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPG 331 Query: 363 FRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLL 422 FRRK+++ + + ++ +FPLY L Y+ AP+ G+ +RKPF+KFL H++SY FLF+L Sbjct: 332 FRRKSIVDKVICIAQVAVLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFIL 391 Query: 423 ILASQRIETAPGGLLWDVS-----HDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWD 477 IL SQR + + ++ L +RG PS +E +++ +V G +W EV++++ Sbjct: 392 ILVSQRADDDFVRIFGTTRMKKELAEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFA 451 Query: 478 MGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQ-PREKWDAWDPM 536 +G++ Y+ +MWN IDF+ NSLYV+ + LR ++ Q E+A Q PREKW +DP Sbjct: 452 VGMKSYLRNMWNFIDFLRNSLYVSVMCLRAFAYIQQATEIARDPQMAYIPREKWHDFDPQ 511 Query: 537 LLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596 L++EGLF+AAN+FS+LKLV++FS+NPHLGPLQ+SL RMV+DI+KFF + LV+FAF+CGL Sbjct: 512 LIAEGLFAAANVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGL 571 Query: 597 NQLLWYYADMEKKRCTVGTALTPNGTL---PDPDACVVWRR---LFETMQTLFWAAFGLV 650 NQLLWY+A +EK +C V P G D+C+ WRR LFE+ Q+LFWA+FG+V Sbjct: 572 NQLLWYFAALEKSKCYV----LPGGEADWGSHGDSCMKWRRFGNLFESSQSLFWASFGMV 627 Query: 651 DLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFAR 710 LD FEL GIK +TRFWG+LMFG+Y +SY +I E +D EWKFAR Sbjct: 628 GLDDFELSGIKSYTRFWGLLMFGSYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFAR 687 Query: 711 SKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQR---RLCGHARAKREHMRTIRAIMR 767 +KLW+SYFE+ T PPPFNVLPS K ++ +R + R R ++E IMR Sbjct: 688 TKLWMSYFEDSATLPPPFNVLPSVKWVIRIFRKSSKTIDRQRSKKRKEQEQFSEYDNIMR 747 Query: 768 NLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVEILRNSGMNTSTANAGAPEVM 827 +LV RYV R+ E+ V+EDD+NE+K +++ R E++EI NSGM+ S+AN + Sbjct: 748 SLVWRYVAAMHRKFENNPVSEDDINEVKSEINTMRYEMLEIFENSGMDVSSANKKERQPR 807 Query: 828 MLRAGGGGGKKNRQKERRLMKGFNIAPGGSLAPVDEF 864 R + ERRLMKGF +AP + +D F Sbjct: 808 PRRI--------KVWERRLMKGFQVAPVQNGCELDAF 836 >UniRef50_P19334 Cluster: Transient receptor potential protein; n=8; Endopterygota|Rep: Transient receptor potential protein - Drosophila melanogaster (Fruit fly) Length = 1275 Score = 790 bits (1954), Expect = 0.0 Identities = 400/807 (49%), Positives = 526/807 (65%), Gaps = 27/807 (3%) Query: 59 EMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXX 118 E +LS EK ++L ERGD+ G +++L+ + T N++C DP+ RSAL+ AI+ Sbjct: 25 EEYILSDVEKNFILSCERGDLPGVKKILEEYQGTDKFNINCTDPMNRSALISAIENENFD 84 Query: 119 XXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSD 178 +E DALLHAISEE+VEAVE LL EE K G+P SWEA+ +TFT D Sbjct: 85 LMVILLEHNIEVGDALLHAISEEYVEAVEELLQWEETNHKEGQPYSWEAVDRSKSTFTVD 144 Query: 179 ITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRX 238 ITPLILAAHR++YEI+K+LLDRGA LP PHDV+CGCD+CV S+ DSLRHS+SRINAYR Sbjct: 145 ITPLILAAHRNNYEILKILLDRGATLPMPHDVKCGCDECVTSQMTDSLRHSQSRINAYRA 204 Query: 239 XXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTS 298 +DP+LTAF+LSWEL+RL A+E EF+ EY E+R Q+F T+LLDH RTS Sbjct: 205 LSASSLIALSSRDPVLTAFQLSWELKRLQAMESEFRAEYTEMRQMVQDFGTSLLDHARTS 264 Query: 299 NELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYE 358 EL+++LN P + G +R L RLKLAI+ +QK FVAHPNVQQLLA+IWY+ Sbjct: 265 MELEVMLNFNH--EPSHDIWCLG--QRQTLERLKLAIRYKQKTFVAHPNVQQLLAAIWYD 320 Query: 359 SVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMF 418 +PGFRRK Q ++V++G FP+YSL YI AP S + +RKPF+KF+ HS SY F Sbjct: 321 GLPGFRRKQASQQLMDVVKLGCSFPIYSLKYILAPDSEGAKFMRKPFVKFITHSCSYMFF 380 Query: 419 LFLLILASQRIETAPGGLL---WDVS--HDEPLSRRGSMPSIVEWLILAWVSGLIWSEVK 473 L LL AS R+ LL W ++ D RGS+P +E I+ ++ LI+ E+K Sbjct: 381 LMLLGAASLRVVQITFELLAFPWMLTMLEDWRKHERGSLPGPIELAIITYIMALIFEELK 440 Query: 474 QLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREM-AMGLQWNQPREKWDA 532 L+ GL EY+ D+WN++D+++N YV + R + V R++ G+ PRE W Sbjct: 441 SLYSDGLFEYIMDLWNIVDYISNMFYVTWILCRATAWVIVHRDLWFRGIDPYFPREHWHP 500 Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592 +DPMLLSEG F+A +FS LKLV+IFS+NPHLGPLQVSL RM++DI+KFF + LV+FAF Sbjct: 501 FDPMLLSEGAFAAGMVFSYLKLVHIFSINPHLGPLQVSLGRMIIDIIKFFFIYTLVLFAF 560 Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPN-GTLPDPD-ACVVWRR---LFETMQTLFWAAF 647 CGLNQLLWYYA++EK +C L P+ D + AC +WRR LFET Q+LFWA+F Sbjct: 561 GCGLNQLLWYYAELEKNKC---YHLHPDVADFDDQEKACTIWRRFSNLFETSQSLFWASF 617 Query: 648 GLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWK 707 GLVDL SF+L GIK FTRFW +LMFG+Y +SYQ+ISERAD EWK Sbjct: 618 GLVDLVSFDLAGIKSFTRFWALLMFGSYSVINIIVLLNMLIAMMSNSYQIISERADTEWK 677 Query: 708 FARSKLWISYFEEGGTAPPPFNVLPSPKSLLYA-WRWLQRRLCGHARAKREHMRTIR-AI 765 FARS+LW+SYFE+GGT PPPFN+ P+ K L R R R E +T+ + Sbjct: 678 FARSQLWMSYFEDGGTIPPPFNLCPNMKMLRKTLGRKRPSRTKSFMRKSMERAQTLHDKV 737 Query: 766 MRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVEILRNSGMNTSTANAGAPE 825 M+ LVRRY+T +QRR + G+TEDD+ E++QD+S+ R EL+EI N+ N P+ Sbjct: 738 MKLLVRRYITAEQRRRDDYGITEDDIIEVRQDISSLRFELLEIFTNN-------NWDVPD 790 Query: 826 VMMLRAGGGGGKKNRQKERRLMKGFNI 852 + G K + ERR++K F I Sbjct: 791 IEKKSQGVARTTKGKVMERRILKDFQI 817 >UniRef50_Q9UBN4 Cluster: Short transient receptor potential channel 4; n=97; Euteleostomi|Rep: Short transient receptor potential channel 4 - Homo sapiens (Human) Length = 977 Score = 691 bits (1708), Expect = 0.0 Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%) Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112 +VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78 Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172 + F V DALLHAI +E V AVE LL+H++ + + P L + Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136 Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232 + FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196 Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292 +N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256 Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352 D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310 Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412 AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+ Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370 Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472 ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+ Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418 Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532 KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470 Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592 W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530 Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652 + GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581 Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712 + FT F G MFGTY +SYQLI++ AD+EWKFAR+K Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641 Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762 LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701 Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816 + +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761 Query: 817 -STANA 821 +ANA Sbjct: 762 IQSANA 767 >UniRef50_Q8I6Y9 Cluster: Trp (Transient receptor potential) channel family protein 2, isoform b; n=3; Caenorhabditis|Rep: Trp (Transient receptor potential) channel family protein 2, isoform b - Caenorhabditis elegans Length = 886 Score = 664 bits (1640), Expect = 0.0 Identities = 337/723 (46%), Positives = 455/723 (62%), Gaps = 22/723 (3%) Query: 65 LEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXXXX 124 L EK++LL ERGD+ R++L T N++C+DPLGR+ALL+AI+ Sbjct: 32 LREKQFLLSCERGDIGSVRKLLAGI-STETFNINCLDPLGRNALLIAIENENIEMIELLL 90 Query: 125 XFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLIL 184 +ET DA+L+AI EE VEAVE +++H E+ K + +A FT DITP++L Sbjct: 91 DHNIETGDAILYAIGEENVEAVEIIVEHLEKMDKFDSERQGVEITEHSA-FTPDITPIVL 149 Query: 185 AAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXXX 244 AAH+D+YE IKL LD+ +P PHDVRC C +C +R EDSLR SRSRINAYR Sbjct: 150 AAHKDNYECIKLFLDKKGTVPHPHDVRCSCPECYVAREEDSLRLSRSRINAYRALTSPSL 209 Query: 245 XXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQIL 304 +DPIL AFELSWEL+RLS +E+EF+T+Y+EL +CQ+F +LD R S EL+++ Sbjct: 210 ICLSARDPILYAFELSWELKRLSFIENEFRTDYEELSQKCQKFCVHMLDQVRGSKELEVV 269 Query: 305 LNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFR 364 LNH A G PE +L+RLKLAI+L QK+FVAHPN QQLL IWYE V R Sbjct: 270 LNHTTNAWHDVTSANYGNPE--KLARLKLAIQLSQKRFVAHPNCQQLLLDIWYEGVESVR 327 Query: 365 RKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLIL 424 N + + + FPL+SL Y+ APHS++G+ +KPFIKFL HS SY FL LLI+ Sbjct: 328 CTNFIYKLIFYILGMLSFPLFSLVYLLAPHSSMGQFAKKPFIKFLSHSGSYIFFLILLIM 387 Query: 425 ASQRIETAPGGLLW-DVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREY 483 ASQR+ L DV E RG P+I+E I WV GLIW E+KQLW+ GL Y Sbjct: 388 ASQRMNVIDNILRTDDVDRKE---TRGPPPTIIECAIFLWVLGLIWVEIKQLWECGLYNY 444 Query: 484 VHDMWNVIDFVTNSLYVATVALRIVSHYQVRREM----AMGLQWNQPREKWDAWDPMLLS 539 ++WN++DF+TNSLY+ T ALR+V++ QV +E ++ + + PR WDAWDP LLS Sbjct: 445 CRNLWNILDFITNSLYLCTTALRVVAYVQVEQEALRANSVHIARHLPRRDWDAWDPTLLS 504 Query: 540 EGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQL 599 E F+ ANIFSSLKLV+IF+V+PHLGPL++SL RMV+DI+KFF++ LV+FAF+CGLNQL Sbjct: 505 ECFFATANIFSSLKLVHIFTVSPHLGPLKISLGRMVIDIVKFFMVYALVLFAFACGLNQL 564 Query: 600 LWYYADMEKKRCTVGTALTPNGTL---------PDPDACVVWRRLFETMQTLFWAAFGLV 650 LWYYA M + C + +L D ++ T +TLFWA FGLV Sbjct: 565 LWYYASMRQNECNLYEQYKNEKSLSYKYEHLKESCDDKYKSCSSIYHTAETLFWALFGLV 624 Query: 651 DLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFAR 710 DL F L + + G +FG+Y +SYQ IS++AD+EWKFAR Sbjct: 625 DLTHFRLKEDHFLSEWTGKTIFGSYCCCSIIVLLNMLIAMMSNSYQYISDQADIEWKFAR 684 Query: 711 SKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGHARAKR-EHMRTIRAIMRNL 769 S+L++ YF++ T PPPFN++PSPKS+ Y +L ++LC + ++ +++R +NL Sbjct: 685 SRLFLEYFDDTATLPPPFNIVPSPKSIYYCLHYLTKKLCNCTKLQQPSKQKSMRVESKNL 744 Query: 770 VRR 772 R Sbjct: 745 AIR 747 >UniRef50_Q4RRG2 Cluster: Chromosome 16 SCAF15002, whole genome shotgun sequence; n=6; Deuterostomia|Rep: Chromosome 16 SCAF15002, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 686 Score = 595 bits (1469), Expect = e-168 Identities = 313/704 (44%), Positives = 441/704 (62%), Gaps = 57/704 (8%) Query: 126 FGVETRDALLHAISEEFVEAVEALLDHEERTRKP-GEPNSWEAL-PPETATFTSDITPLI 183 + V DALLHAI ++ V AVE LL+H +KP GE L + FT DITP+I Sbjct: 10 YNVYVGDALLHAIRKQVVGAVELLLNH----KKPHGEKQVLSVLLDRHFSDFTPDITPII 65 Query: 184 LAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXX 243 LAAH ++YEIIKLLL RG +P+PH V C C +CV DSLRHSRSR+N Y+ Sbjct: 66 LAAHINNYEIIKLLLQRGVSIPQPHAVHCNCMECVSCSDVDSLRHSRSRLNIYKALASPS 125 Query: 244 XXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQI 303 +DP LTAF+LSWEL+ LS +E+EFK+EY EL C++FA LLD TR+S EL+I Sbjct: 126 LIALSSEDPFLTAFKLSWELKELSTVENEFKSEYGELSRMCKQFAKDLLDQTRSSKELEI 185 Query: 304 LLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPGF 363 +LN+ ++ PL + + L+RLKLAIK QK+FVA PN QQLLAS WY+ PG+ Sbjct: 186 ILNYRDDSN---PLLDENPND---LARLKLAIKYSQKEFVAQPNCQQLLASRWYDEFPGW 239 Query: 364 RRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLI 423 RR++ + + IG +FPL +AY+ +P S G +RKPFIKF+CH+ASY FLFLL Sbjct: 240 RRRHWAAKLLICIFIGLLFPLLCIAYLISPKSRYGLFIRKPFIKFICHTASYLTFLFLLF 299 Query: 424 LASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREY 483 LA+Q I + L D+ +G P+ VEW+IL WV G IW+E+KQ+WD G ++Y Sbjct: 300 LAAQHIASP----LCDL--------QGPPPTTVEWMILPWVIGFIWNEIKQMWDSGFQDY 347 Query: 484 VHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLF 543 + D WN++DF+ NSLY+AT++L+I+++ + + + R W+ W P L++E LF Sbjct: 348 IGDWWNLVDFIMNSLYIATISLKIIAYVKYSEQ--------KHRNDWEMWHPTLVAESLF 399 Query: 544 SAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYY 603 + ANIFSSL+L+ +F+VN HLGPLQ+SL RM+LDILKFF + LV+ AF+ GLNQL +YY Sbjct: 400 AIANIFSSLRLICLFTVNSHLGPLQISLGRMLLDILKFFFIYWLVLLAFANGLNQLYFYY 459 Query: 604 ADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIF 663 +C + N + LF+ ++ L+W FGL+ L+ +++ F Sbjct: 460 ETERTNKCKGIHCIQQNN---------AFSTLFDRVECLYWRIFGLISLNVTKVEREHEF 510 Query: 664 TRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGT 723 T F G MFG Y +SYQ I+ AD+EWKFAR+KLW+SYFEEGGT Sbjct: 511 TEFVGSTMFGAYNVISLVVLLNMLIAMMNNSYQHIANHADIEWKFARTKLWMSYFEEGGT 570 Query: 724 APPPFNVLPSPKSLLYAWRWLQRRLCGHARAKR------------EHMR---TIRAIMRN 768 P PFN++PSPKS+ Y + W+++ L AKR E++R + +++N Sbjct: 571 LPAPFNIIPSPKSVYYLFAWIKKHLFKRRSAKRLETFETLGRRAAENVRINHEYQKVLKN 630 Query: 769 LVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRN 811 LVRRYV R A++ +TE++ E+KQD+S+FR E++ ++++ Sbjct: 631 LVRRYVAAVIRDAKTERSLTEENFKELKQDISSFRYEVLGMMKS 674 >UniRef50_Q8IS32 Cluster: Transient receptor potential ion channel C; n=6; Coelomata|Rep: Transient receptor potential ion channel C - Limulus polyphemus (Atlantic horseshoe crab) Length = 923 Score = 506 bits (1248), Expect = e-141 Identities = 275/717 (38%), Positives = 407/717 (56%), Gaps = 26/717 (3%) Query: 56 PHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXX 115 P ++ + +E+ +L ERGD R LQ +NV+C + LGRSA+ +A+D Sbjct: 32 PLKDNQTMDPKERTFLEAAERGDKHTIIRCLQPPNP---VNVNCTNILGRSAIQIAVDNE 88 Query: 116 XXXXXXXXXXFG-VETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSW---EALPPE 171 V+ DALLHAI E + VE L++H T N W E Sbjct: 89 NVEIVELLLMQDMVKIGDALLHAIREGVYKIVEMLINHPSITAGMLS-NDWAKSRQQGEE 147 Query: 172 TATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRS 231 ++ ++ DI+P+ILAAH + +EI++LLL RGA + PH + C C C DSLR+S Sbjct: 148 SSDYSPDISPVILAAHCNQFEILQLLLSRGAMIETPHSLSCCCQKCEEGIHTDSLRYSLR 207 Query: 232 RINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATAL 291 +I+ YR DPILTAF+LSWEL L+ E+EFK Y EL QC+ ++ L Sbjct: 208 KIHTYRALASPAWISLTSDDPILTAFKLSWELEHLAMRENEFKEIYLELSNQCKCYSCDL 267 Query: 292 LDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQL 351 LD R++ E+ +LN + + + E + +++ L+RLKLA+K QK+F+AHPN QQL Sbjct: 268 LDLCRSTEEVIAVLNKQSDSDSEDDEDEENS-DKLTLARLKLALKYEQKQFIAHPNCQQL 326 Query: 352 LASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCH 411 L SIWYE +P +RR N +++ + PL +L Y+ P S +GR +R PF+KF+ H Sbjct: 327 LTSIWYEGLPVWRRWNGVMKIFMCFGLITCMPLIALYYLTFPMSKLGRVVRSPFMKFIYH 386 Query: 412 SASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSE 471 SAS+ FL LL+LAS R+E S + RG PS++EWL+ WV+G++W+E Sbjct: 387 SASFGFFLLLLVLASTRLEG---------SERSKQNIRGPPPSMIEWLVFFWVTGMVWAE 437 Query: 472 VKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWD 531 KQLW+ G++ YV WN +DF+ SL++ +LR +S + ++ E G + + R +W Sbjct: 438 CKQLWEEGIKAYVRQWWNWLDFIMLSLFLTAFSLRAMSFFLIQSEQ-YGPRILE-RARWP 495 Query: 532 AWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFA 591 DP L++EG+F+ AN+FS +++Y+F NPHLGPLQ+SL M++DI KF + LV+ + Sbjct: 496 NNDPTLIAEGVFAMANVFSFARIIYLFQTNPHLGPLQISLGCMIIDIAKFLFIFFLVLTS 555 Query: 592 FSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVD 651 F+CGLNQL WYY D + + C N T+ + + + TL W+ FG++ Sbjct: 556 FACGLNQLYWYY-DTDSEICDTKVIGGENVTVNCQRNTDAFITIDSSYTTLLWSLFGVIP 614 Query: 652 LDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARS 711 + + + FT++ G + G Y S+Q I + AD EWKFARS Sbjct: 615 IKDLKAREDQAFTKWVGQALLGAYMIMAMTVMINMLIAMMSRSFQDIEDHADREWKFARS 674 Query: 712 KLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC----GHARAKREHMRTIRA 764 KLW+ YF+EG T PPPFN++ SPKS+LY R L + LC G A +R+ R +A Sbjct: 675 KLWMGYFDEGSTLPPPFNIIISPKSILYFIRGL-KHLCVTMFGKASLRRQSTRNTKA 730 Score = 44.8 bits (101), Expect = 0.012 Identities = 20/43 (46%), Positives = 29/43 (67%) Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807 +M+ LV RY+ +++ GV EDD+ EIKQD+S+ R EL E Sbjct: 778 VMKRLVSRYIHQTKKQLRQDGVNEDDLLEIKQDISSLRYELRE 820 >UniRef50_P48995 Cluster: Short transient receptor potential channel 1; n=32; Euteleostomi|Rep: Short transient receptor potential channel 1 - Homo sapiens (Human) Length = 793 Score = 491 bits (1211), Expect = e-137 Identities = 282/768 (36%), Positives = 434/768 (56%), Gaps = 55/768 (7%) Query: 64 SLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXXX 123 +L EK +LL ++GD +++L+ +G +N++CVD LGR+A+ + I+ Sbjct: 45 TLNEKLFLLACDKGDYYMVKKILEE-NSSGDLNINCVDVLGRNAVTITIENENLDILQLL 103 Query: 124 XXFGVETRDALLHAISEEFVEAVEALLDHE-ERTRKPGEPNSWEALP-PETATFTSDITP 181 +G ++ DALL AI E V AV+ LL+H +R+ +P E + PE +T T D+ P Sbjct: 104 LDYGCQSADALLVAIDSEVVGAVDILLNHRPKRSSRPTIVKLMERIQNPEYST-TMDVAP 162 Query: 182 LILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXX 241 +ILAAHR++YEI+ +LL + LP+PH V C C C ++DSLRHSR R++ YR Sbjct: 163 VILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLAS 222 Query: 242 XXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNEL 301 +DPIL AFELS +L+ LS +E EF+ +Y+EL QC+ FA LL R S EL Sbjct: 223 PALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSREL 282 Query: 302 QILLNHEKGASPQAPLTEPG-APERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESV 360 +++LNH S PL + G ERM LSRLKLAIK QK+FV+ N QQ L ++W+ + Sbjct: 283 EVILNH---TSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQM 339 Query: 361 PGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLF 420 G+RRK + ++ +G +P+ SL Y+ AP S GR + PF+KF+ H ASYF FL Sbjct: 340 SGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLL 399 Query: 421 LLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGL 480 LL L S V +++ + G +++L++ W+ G+IWS++K+LW GL Sbjct: 400 LLNLYSL------------VYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGL 447 Query: 481 REYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSE 540 +++ + N + FV NSLY+AT AL++V+H + + A R+ WDA+ P L++E Sbjct: 448 EDFLEESRNQLSFVMNSLYLATFALKVVAHNKF-HDFA-------DRKDWDAFHPTLVAE 499 Query: 541 GLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL 600 GLF+ AN+ S L+L ++++ + LGPLQ+S+ +M+ D KF + +LV+F+F+ GL QL Sbjct: 500 GLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLY 559 Query: 601 -WYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSF--EL 657 Y E+K C G + + + T LFW F L + F Sbjct: 560 DKGYTSKEQKDCV--------GIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRF 611 Query: 658 DGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISY 717 + F G ++ GTY S+QLI+ D EWKFAR+KLW+SY Sbjct: 612 SYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSY 671 Query: 718 FEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGH---ARAKREHM------------RTI 762 F++ T PPPFN++PSPK++ Y L + +C H + KR++ Sbjct: 672 FDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENY 731 Query: 763 RAIMRNLVRRYVT-VQQRRAESGGVTEDDVNEIKQDVSAFRCELVEIL 809 + +M LV RY+T ++Q+ + T +++NE++QD+S FR E+ ++L Sbjct: 732 QKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLL 779 >UniRef50_P34586 Cluster: Transient-receptor-potential-like protein; n=3; Caenorhabditis|Rep: Transient-receptor-potential-like protein - Caenorhabditis elegans Length = 1027 Score = 449 bits (1107), Expect = e-124 Identities = 273/794 (34%), Positives = 427/794 (53%), Gaps = 56/794 (7%) Query: 62 VLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXX 121 ++S EE+++L E G+ + L D +NV+C+D +GR+AL +A+D Sbjct: 45 MISPEERRFLEAAELGNKPTLQECLDYDGDR-RLNVNCLDSMGRTALEIAVDNENMEVVE 103 Query: 122 XXXXF-GVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPE---TATFTS 177 + +ALL AI E VE L++H TR+ +AL P +A ++S Sbjct: 104 LLLQQPDIRIGNALLCAIREGVYRLVEVLVNHPNITREMLGDGWSQALDPSEAASAEYSS 163 Query: 178 DITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYR 237 DI+P+ILAA + +EI+++L+ + A + +PH C C+ C R R DSL++S RIN +R Sbjct: 164 DISPVILAAQLNQFEILQMLIRKDASIEKPHRHSCICETCDRERLNDSLQYSLKRINTFR 223 Query: 238 XXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRT 297 DPIL+AF+LSW+L+RL+ EHEFK Y +L QC++++ LL R+ Sbjct: 224 ALASPAWMSLTSPDPILSAFKLSWDLQRLAFEEHEFKETYLQLSEQCKQYSCDLLSQCRS 283 Query: 298 SNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWY 357 S E+ +LN K + + A ++ LSRLKLAIK QK FV+HP+ QQLL SIWY Sbjct: 284 SEEVIAILN--KDGNVNDDNIDVWA-SKLSLSRLKLAIKYEQKAFVSHPHCQQLLTSIWY 340 Query: 358 ESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFM 417 E +P +R + ++P++ L YI P S +GR +R PF+KF +S S+ Sbjct: 341 EGIPYRQRSGTWANFFLYAFLLFLWPIFCLMYILMPKSRLGRLVRSPFMKFFYYSVSFAT 400 Query: 418 FLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWD 477 FL LL A+ G ++ S RG + VE L+ WV G++WSE+KQLW+ Sbjct: 401 FLGLLTWATFEDYRYEKGERGGMTR---ASDRGPPATWVESLVFTWVIGMLWSEIKQLWE 457 Query: 478 MGLREYVHDMWNVIDFVTNSLYVATVALRIVSHY-QVRREMAMGLQWNQPREKWDAWDPM 536 G + Y+ WN +DF+ LY+ T+++R+ ++Y RE R W + +PM Sbjct: 458 EGFKRYMRQWWNWLDFLMICLYLCTISIRLSAYYIFTYREDPYRY---TVRTYWTSEEPM 514 Query: 537 LLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596 L++E LF+ N+FS +++Y+F NP+LGPLQ+SL M++D+ KF + +L+I +FS GL Sbjct: 515 LVAEALFAVGNVFSFARIIYLFQTNPYLGPLQISLGCMLVDVAKFCFIFVLIISSFSIGL 574 Query: 597 NQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFE 656 QL WYY D C G + V+ + ++ TL W+ F + + + Sbjct: 575 AQLYWYY-DPNTDVCLPGATCKHSSN--------VFSSIADSYLTLLWSLFSITKPEDTD 625 Query: 657 LDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWIS 716 + T++ G MF Y HS+Q+I++ AD+EWKF R+KLW++ Sbjct: 626 VVENHKITQWVGQGMFIMYHCTSIIVLLNMLIAMMSHSFQIINDHADLEWKFHRTKLWMA 685 Query: 717 YFEEGGTAPPPFNVLPSPKSLLYAW-------RWL------QR-------RLCGHARAKR 756 +F+EG + PPPFN++ +PKSL+Y RWL Q+ R G++R + Sbjct: 686 HFDEGSSLPPPFNIIVTPKSLIYVMNCLFNTVRWLLGKYTYQKNRNRATIRRPGYSRKRN 745 Query: 757 EHMR------------TIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCE 804 E + T I+ LV R++ ++ + GV EDD++EIKQD+S+ R E Sbjct: 746 EMEKSGGHDDDSLKPLTYADIITRLVARFIHQTKKDMKMDGVNEDDLHEIKQDISSLRYE 805 Query: 805 LVEILRNSGMNTST 818 L + R + +S+ Sbjct: 806 LRDDRRREIVRSSS 819 >UniRef50_Q96P03 Cluster: Transient receptor potential channel 4 zeta splice variant; n=10; Eutheria|Rep: Transient receptor potential channel 4 zeta splice variant - Homo sapiens (Human) Length = 804 Score = 446 bits (1099), Expect = e-123 Identities = 233/500 (46%), Positives = 319/500 (63%), Gaps = 46/500 (9%) Query: 339 QKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVG 398 +K+FVA PN QQLLAS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G Sbjct: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183 Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEW 458 +RKPFIKF+CH+ASY FLFLL+LASQ I+ + L+R+G P+IVEW Sbjct: 184 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSD------------LNRQGPPPTIVEW 231 Query: 459 LILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMA 518 +IL WV G IW E+KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A Sbjct: 232 MILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS---A 288 Query: 519 MGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDI 578 + PRE WD W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDI Sbjct: 289 LN-----PRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDI 343 Query: 579 LKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFET 638 LKF + LV+ AF+ GLNQL +YY + + C N + LFET Sbjct: 344 LKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNA---------FSTLFET 394 Query: 639 MQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLI 698 +Q+LFW+ FGL++L + FT F G MFGTY +SYQLI Sbjct: 395 LQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLI 454 Query: 699 SERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKRE 757 ++ AD+EWKFAR+KLW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E Sbjct: 455 ADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE 514 Query: 758 HMRTI--------------RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFR 802 TI + +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR Sbjct: 515 SFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFR 574 Query: 803 CELVEILRNSGMNT-STANA 821 E++ +LR S ++T +ANA Sbjct: 575 FEVLGLLRGSKLSTIQSANA 594 Score = 83.0 bits (196), Expect = 4e-14 Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 3/102 (2%) Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112 +VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78 Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEE 154 + F V DALLHAI +E V AVE LL+H++ Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120 >UniRef50_UPI000069F43F Cluster: Short transient receptor potential channel 6 (TrpC6).; n=1; Xenopus tropicalis|Rep: Short transient receptor potential channel 6 (TrpC6). - Xenopus tropicalis Length = 806 Score = 445 bits (1096), Expect = e-123 Identities = 277/785 (35%), Positives = 420/785 (53%), Gaps = 69/785 (8%) Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI--DXXXXXXX 120 LS +E+++L E G++ RR+++ R +NV+CVD +G++AL +A+ + Sbjct: 21 LSADEERFLDAAEYGNIPVVRRMMEECRS---LNVNCVDYMGQNALQLAVANEHLEITEL 77 Query: 121 XXXXXFGVETRDALLHAISEEFVEAVEALLDH---EERTRKPGEPNSWE-------ALPP 170 DALL AIS+ +V VEA+L H E R P+ E A Sbjct: 78 LLKKENLARVGDALLLAISKGYVRIVEAILSHPSFSEGKRLTTSPSQSEFQHDDFYAYDE 137 Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230 + F+ DITP+ILAAH YEI+ LL +GA++ PHD C C +C ++ DS HSR Sbjct: 138 DGTRFSQDITPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSEKQKHDSFSHSR 197 Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290 SRINAY+ +DP++TA ELS EL L+ +E EFK +Y++L +QC++F Sbjct: 198 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVG 257 Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350 LLD R + E++ +LN + + + G P L RLKLAIK KKFVAHPN QQ Sbjct: 258 LLDLCRNTEEVEAILNGDVDTN-GGNVELDGRPS---LCRLKLAIKYEVKKFVAHPNCQQ 313 Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410 L SIWYE++ G R++ ++ ++ + P ++ Y AP S +G+ +R PF+KF+ Sbjct: 314 QLLSIWYENLSGLRQQTTAVKFLVVLAVAMGLPFLAMVYWIAPCSKLGKIMRGPFMKFVA 373 Query: 411 HSASYFMFLFLLIL-ASQRIETAPGGLLWD-----VSHDEPLSRRGSMPSIVEWLILAWV 464 H+AS+ +FL LL++ A+ R++ G +L + E + + S +E L+ + Sbjct: 374 HAASFTIFLGLLVMNAADRLKDR-GTILTPFIPLYIKPSETIDIQIS-GIFLELLLGQCL 431 Query: 465 SGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR--------E 516 G+IWSE K++W G REY+ ++WN++DF +++ A+ R ++ + R E Sbjct: 432 IGMIWSECKEIWSQGPREYMFELWNILDFGMLAIFAASFIARFMAFWHASRAQNYVDDDE 491 Query: 517 MAMGLQ----------WNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGP 566 L + R KW DP ++SEGL++ A + S ++ YI N GP Sbjct: 492 SIKDLSSATLPPEIKYYTLARIKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGP 551 Query: 567 LQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDP 626 LQ+SL R V DI KF V+ I+V AF G+ L YY ++ Sbjct: 552 LQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYLGAKQN----------------- 594 Query: 627 DACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXX 686 DA + + E+ +TLFWA FGL ++ S ++ F G +++G Y Sbjct: 595 DA---FTTVEESFKTLFWAIFGLSEVKSVVINYGHKFIENIGYVLYGVYNVTMVIVLLNM 651 Query: 687 XXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLY----AWR 742 +S+Q I + ADVEWKFAR+KLW SYFEEG T P PFN++PSPKS +Y Sbjct: 652 LIAMINNSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSFVYIALKVKG 711 Query: 743 WLQRRLCGHARAKREHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFR 802 +L +R +++ +E + IM+ L++RYV Q ES V E ++ EIKQD+S+ R Sbjct: 712 FLNKRFPCNSKGLQEDSEMNKKIMKRLIKRYVLKAQIDKESDEVNEGELKEIKQDISSLR 771 Query: 803 CELVE 807 EL+E Sbjct: 772 YELLE 776 >UniRef50_Q9Y210 Cluster: Short transient receptor potential channel 6; n=123; Euteleostomi|Rep: Short transient receptor potential channel 6 - Homo sapiens (Human) Length = 931 Score = 438 bits (1080), Expect = e-121 Identities = 262/733 (35%), Positives = 395/733 (53%), Gaps = 68/733 (9%) Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122 LS+EE+++L E G++ R++L+ +NV+CVD +G++AL +A+ Sbjct: 95 LSIEEERFLDAAEYGNIPVVRKMLEECHS---LNVNCVDYMGQNALQLAVANEHLEITEL 151 Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDHE---ERTRKPGEPNSWE-------ALPP 170 +R DALL AIS+ +V VEA+L H E R P+ E A Sbjct: 152 LLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDE 211 Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230 + F+ D+TP+ILAAH YEI+ LL +GA++ PHD C C+DC + ++ DS HSR Sbjct: 212 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSR 271 Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290 SRINAY+ +DP++TA ELS EL L+ +E EFK +Y++L +QC++F Sbjct: 272 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVG 331 Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350 LLD R + E++ +LN + + G R LSRLKLAIK KKFVAHPN QQ Sbjct: 332 LLDLCRNTEEVEAILNGD------VETLQSGDHGRPNLSRLKLAIKYEVKKFVAHPNCQQ 385 Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410 L SIWYE++ G R++ M ++ ++ + P +L Y AP S +G+ +R PF+KF+ Sbjct: 386 QLLSIWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWFAPCSKMGKIMRGPFMKFVA 445 Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSG 466 H+AS+ +FL LL++ A+ R E P D + + + S S +E LI++WV G Sbjct: 446 HAASFTIFLGLLVMNAADRFEGTKLLPNETSTD-NAKQLFRMKTSCFSWMEMLIISWVIG 504 Query: 467 LIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR----------- 515 +IW+E K++W G +EY+ ++WN++DF +++ A+ R ++ + + Sbjct: 505 MIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTL 564 Query: 516 ----EMAMG---LQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQ 568 ++ +G +N R KWD DP ++SEGL++ A + S ++ YI N GPLQ Sbjct: 565 KDLTKVTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQ 624 Query: 569 VSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDA 628 +SL R V DI KF V+ I+V AF G+ L YY ++ Sbjct: 625 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNE------------------ 666 Query: 629 CVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXX 688 + + E+ +TLFWA FGL ++ S ++ F G +++G Y Sbjct: 667 --AFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLI 724 Query: 689 XXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAW----RWL 744 S+Q I + ADVEWKFAR+KLW SYFEEG T P PFN++PSPKSL Y +W+ Sbjct: 725 AMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLKLKKWI 784 Query: 745 QRRLCGHARAKRE 757 GH + +E Sbjct: 785 SELFQGHKKGFQE 797 Score = 45.6 bits (103), Expect = 0.007 Identities = 23/57 (40%), Positives = 33/57 (57%) Query: 751 HARAKREHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807 H + R + IM+ L++RYV Q ES V E ++ EIKQD+S+ R EL+E Sbjct: 844 HLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLE 900 >UniRef50_UPI0000E494DE Cluster: PREDICTED: similar to transient receptor potential Ca2+ channel 6A isoform 2; n=2; Deuterostomia|Rep: PREDICTED: similar to transient receptor potential Ca2+ channel 6A isoform 2 - Strongylocentrotus purpuratus Length = 1360 Score = 349 bits (857), Expect = 3e-94 Identities = 270/858 (31%), Positives = 422/858 (49%), Gaps = 124/858 (14%) Query: 58 QEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXX 117 +E +LS +E +L E GD+ +++L+ + D + C D R+AL ++ + Sbjct: 178 KEHDLLSKDELNFLQAAEIGDLPTVKQMLE-SDDLAPKLLRCTDYKDRTALEVSTENEHL 236 Query: 118 XXXXXXXXFGVETRD------ALLHAISEEFVEAVEALLDH------EERTRKPGEPNSW 165 G D +L+ AIS+ ++ +ALL+H +++ R N + Sbjct: 237 EIVEFLVQKGGRKLDIQAIQESLMLAISKGYLRITQALLNHPVHQQSKDKFRLGSLTNYY 296 Query: 166 EALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDS 225 + + F D+TPL+LAAH + +II+LLL+RG + +PH+ C C C ++ D Sbjct: 297 QR--KNNSKFAQDVTPLMLAAHCNEIDIIRLLLNRGDTIKKPHNSLCQCTYCSNKKQFDP 354 Query: 226 LRHSRSRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQ 285 L+HS + N YR DPIL+AF LS EL + +E EFK EY++L QC+ Sbjct: 355 LKHSLAGFNTYRALASPAFIALTSPDPILSAFLLSQELGTNARIEKEFKNEYRDLARQCK 414 Query: 286 EFATALLDHTRTSNELQILLN----------HEKGAS-PQAPLTEPGAPERMRLSRLKLA 334 EFA+ LLD + S E++ +LN HE+ + ++ + E G+ LSRLKLA Sbjct: 415 EFASDLLDMCQNSEEVRTILNNEANTLDESEHERATNWLKSEVGEEGSSRTPTLSRLKLA 474 Query: 335 IKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPH 394 IKLRQK+FVAH + Q LA++WY + P +R ++ + V I P ++L Y AP+ Sbjct: 475 IKLRQKQFVAHSHCQHELATLWYRNFPSWRLMSLPKKVFVNVLIVLGLPFFTLCYYLAPY 534 Query: 395 SAVGRTLRKPFIKFLCHSAS---YFMFLF--------------------LLILASQRIET 431 S +G + P +KF+ +SAS + + +F L L +R+ T Sbjct: 535 SKLGEFVSSPLVKFILYSASYFVFLLVIFIESLYAQTYQNSFHEEKEGKLTSLLRERLNT 594 Query: 432 APGGLLW---DVSHDEPLSR-RGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDM 487 L D+ + + R R + +E +IL ++ G +W E+KQLW GL+ Y+ + Sbjct: 595 TSDTCLSIFPDLEDENYVIRLRFFALTPLEIVILIFLMGFLWGEIKQLWAEGLQAYLASV 654 Query: 488 WNVIDFVTNSLYVATVALRIVSHYQVRREMAMGL------------QWNQP--------- 526 WN ID +LY+A+ L I+S R +A+ N P Sbjct: 655 WNWIDIAMLNLYLASCTLNILS--VTRASLAIDFFMTNVNAPCLYKNGNDPIANRYFYFL 712 Query: 527 ---REKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFV 583 R W DP+ +SE L++ AN+ S +L YI V+ LGPLQ+SL RM+ DIL+F V Sbjct: 713 QRERSMWHNDDPVFVSEALYALANVLSFCRLSYILPVSEFLGPLQISLGRMLGDILRFAV 772 Query: 584 LDILVIFAFSCGLNQLLWYYADME-----KKRCTVGTALTPNGTLPDPDACVVWRRLFET 638 + I+V AF C + L + Y D + + T+ AL G DP RL Sbjct: 773 VFIVVFLAFFCSMFNLYYSYEDSKFGNFGQAFLTLFWALFGLGNPSDP-------RLRHN 825 Query: 639 MQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLI 698 + T G L++ G I T +G +++ Y +S+Q I Sbjct: 826 ITT------GNATLEAGGKGGYLI-TESFGTMLYMIYYVVMGLVMLNMLIAMMSNSFQEI 878 Query: 699 SERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRL---------- 748 + DVEWKFAR++LW+SYFE+G T P PFN++PSPKS ++ ++W+ RR+ Sbjct: 879 NSEQDVEWKFARAQLWMSYFEKGATIPVPFNIIPSPKSFIHLYKWVARRVTRFRQGSPSR 938 Query: 749 ------CGHAR------AKREHMR----TIRAIMRNLVRRYVTVQQRRAESGGVTEDDVN 792 G R R +R T +I + +++RY+ QR E+ V E +++ Sbjct: 939 DNNQVPLGERRNGVFNILNRLELRREESTHESITKGIIKRYLFKLQRDKENDEVNEGELD 998 Query: 793 EIKQDVSAFRCELVEILR 810 EIK D+S+ R EL+E LR Sbjct: 999 EIKNDISSLRFELMEQLR 1016 >UniRef50_UPI000058480E Cluster: PREDICTED: similar to putative capacitative calcium channel; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to putative capacitative calcium channel - Strongylocentrotus purpuratus Length = 933 Score = 349 bits (857), Expect = 3e-94 Identities = 256/838 (30%), Positives = 402/838 (47%), Gaps = 115/838 (13%) Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122 L+ E++ +L G+ A R +++ + D + + D +AL +A + Sbjct: 20 LAEEDRSFLRVASLGNFAKVREIMENSSDPKKL-MQLTDFKDCTALEIATEAEHFEIVEY 78 Query: 123 XXX-FG-----VETRDALLHAISEEFVEAVEALLDHEERTRKP----GEPNSWEA-LPPE 171 FG + + L+ AIS+ ++ + +L+H K G + + L Sbjct: 79 LVQEFGDLMDEIHLHECLMLAISKGYLRITQVILNHPLSDVKLKGTCGRQDRFHFYLTKN 138 Query: 172 TATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRS 231 + F D+TPL+LAA + EII+LLLDRG + EPH + C C DC ++ D L S + Sbjct: 139 NSKFDRDLTPLMLAAQCNEAEIIRLLLDRGEYIQEPHAIFCSCKDCTEAKENDPLLRSLA 198 Query: 232 RINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATAL 291 ++ Y+ DPILTAF LS +L L+++E EFK EY+EL +C++FA+ L Sbjct: 199 GLHTYQALGSEAYICLTSHDPILTAFLLSEKLTELASIEKEFKNEYRELVKRCKQFASDL 258 Query: 292 LDHTRTSNELQILLNHEKGASPQAPLTE------------PGAPER---MRLSRLKLAIK 336 LD +T+ E+Q +L E + E P PE L RL+LAIK Sbjct: 259 LDMCQTTAEVQTILKQEATTQGEVFAAEGANTLRKRRGAKPILPENDSDFSLPRLELAIK 318 Query: 337 LRQKKFVAHPNVQQLLASIWYESVPGFRRK-NMLLQAAEMVRIGAMFPLYSLAYIAAPHS 395 RQK+FVAHP+ Q L+++WY+ P R+ + L++ V + A P +LAY P+ Sbjct: 319 FRQKQFVAHPHCQHHLSTLWYKGFPSKTRQWHPLIKCLATVCMIAAIPFLTLAYWICPNK 378 Query: 396 AVGRTLRKPFIKFLCHSASYFMFLFLLILAS-------------------QRIETAPGGL 436 VG +R P KF+ H+A Y FL +L L S + Sbjct: 379 -VGDFMRSPRTKFMLHAAMYVTFLLILFLESVVSKGFRNDDHQDEFIKSHMNCTYLSQAV 437 Query: 437 LWDVSHDEPLSR-RGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVT 495 H++ R R S ++ LI+ +V G++W+E+KQ++ G + Y+ +WN ID Sbjct: 438 RNQTFHEDTAPRVRPDCFSPLQILIVVFVMGMLWAEIKQIFREGYKIYLQSLWNWIDIAM 497 Query: 496 NSLYVATVALRIVSHYQVRREMA-----------------MGLQW-NQPREKWDAWDPML 537 ++ ++++++R + Y+V MA L+W R WD +DP L Sbjct: 498 LNILISSISIRAIVVYKVTNSMAYFDENVDACEDENGQATKHLRWLLADRTLWDQYDPTL 557 Query: 538 LSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLN 597 ++E L++ AN+ S +L+YI VN LGPL +SL +MV IL+FF + I+V AF C L Sbjct: 558 IAEALYAIANVLSFSRLLYILPVNEFLGPLNISLQKMVGQILRFFSVFIVVFLAFFCALT 617 Query: 598 QLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLD--SF 655 L Y +R +QTL WA FGL D S+ Sbjct: 618 NLYRNYPQESN-----------------------FRGYVNAIQTLIWALFGLSDAADVSY 654 Query: 656 ELD--------GIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWK 707 D G K T G+ ++ Y S+Q I + DVEWK Sbjct: 655 PSDAPCDQESCGQKT-TELVGVCLYMAYHLVMALVMLNMLIAMMSTSFQEIHDDEDVEWK 713 Query: 708 FARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGHARAK------------ 755 FARS+LW+SYFE G T P P N++PSPKS+ Y ++WL++ LC + K Sbjct: 714 FARSQLWMSYFERGATLPLPMNIIPSPKSIYYFFKWLKKTLCPNCGKKNITMTQQLPRRP 773 Query: 756 --REHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVEILRN 811 R+ + T ++M+ +++RY+ Q E E ++ EIK D+S+FR E++E +++ Sbjct: 774 GIRKQVSTHESLMKTVIKRYLFKLQNDKEGEEGAEGELEEIKNDISSFRFEVMERMKH 831 >UniRef50_Q9R244 Cluster: Short transient receptor potential channel 2; n=92; Euteleostomi|Rep: Short transient receptor potential channel 2 - Mus musculus (Mouse) Length = 1172 Score = 339 bits (833), Expect = 2e-91 Identities = 209/587 (35%), Positives = 302/587 (51%), Gaps = 48/587 (8%) Query: 175 FTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRIN 234 F +TPL LA +D YEI +LL+D+G + PH V C C +C +RR D L+ S SRIN Sbjct: 428 FAPGVTPLTLACQKDLYEIAQLLMDQGHTIARPHPVSCACLECSNARRYDLLKFSLSRIN 487 Query: 235 AYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDH 294 YR +D +L AF+LS ELRRL+ E EFK +Y L CQ++ LL Sbjct: 488 TYRGIASRAHLSLASEDAMLAAFQLSRELRRLARKEPEFKPQYIALESLCQDYGFELLGM 547 Query: 295 TRTSNELQILLN---HEKGASPQAPLTEPGAPERM-RLSRLKLAIKLRQKKFVAHPNVQQ 350 R +E+ +LN + P+A E + L+RL+LA+ QK+FVAHP QQ Sbjct: 548 CRNQSEVTAVLNDLGEDSETEPEAEGLGQAFEEGIPNLARLRLAVNYNQKQFVAHPICQQ 607 Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410 +L+SIW ++ G+R + + I P + Y AP S +GR L+ P +KFL Sbjct: 608 VLSSIWCGNLAGWRGSTTIWRLFVASLIFLTMPFLCIGYWLAPKSQLGRLLKIPVLKFLL 667 Query: 411 HSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEW-LILAWVSGLIW 469 HSASY FL L+ S +ET + + +G S+ E L + WV+G +W Sbjct: 668 HSASYLWFLIFLLGESLVMET------------QLSTFKGRSQSVWETSLHMIWVTGFLW 715 Query: 470 SEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSH---YQVRREMAMGLQWN-- 524 E K++W GLR Y+ D WN +D V SLY+A+ ALR++ Y R+ + Sbjct: 716 FECKEVWIEGLRSYLLDWWNFLDVVILSLYLASFALRLLLAGLAYMHCRDASDSTTCRCF 775 Query: 525 --QPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFF 582 R +W DP L+E LF+ ++ S +L YI + LG LQ+S+ +M+ D+++F Sbjct: 776 TTAERSEWRTEDPQFLAEVLFTVTSMLSFTRLAYILPAHESLGTLQISIGKMIDDMIRFM 835 Query: 583 VLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTL 642 + ++++ AF CGLN + Y + EK +G ET Q L Sbjct: 836 FILMIILTAFLCGLNNIYVPYQESEK----LG-------------------NFNETFQFL 872 Query: 643 FWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERA 702 FW FG+ + ++ + F G M+G + +S+Q I + A Sbjct: 873 FWTMFGMEEHTVVDMPQF-LVPEFVGRAMYGIFTIVMVIVLLNMLIAMITNSFQKIEDDA 931 Query: 703 DVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC 749 DVEWKFARSKL++SYF EG T P PFN+LPSPK+ Y R + R LC Sbjct: 932 DVEWKFARSKLYLSYFREGLTLPVPFNILPSPKAAFYLVRRIFRFLC 978 >UniRef50_Q4VDB0 Cluster: Transient receptor potential channel C2; n=2; Danio rerio|Rep: Transient receptor potential channel C2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1140 Score = 338 bits (832), Expect = 3e-91 Identities = 213/638 (33%), Positives = 322/638 (50%), Gaps = 54/638 (8%) Query: 129 ETRDALLHAISEEFVEAVEALLDH--EERTRKPGEPNSWEAL---PPETATFTSDITPLI 183 + +ALL A+ V+ LLD +E+ K + A+ + + F +TPL Sbjct: 86 QIHEALLVAVDTNQPRVVKRLLDRLDQEKGNKMDVRSFSMAIFDHSIDDSQFAPGVTPLT 145 Query: 184 LAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXX 243 LA +D Y+I+ +L +G ++P PH + C C +C R+ D L+ S SRIN YR Sbjct: 146 LACQKDLYDIVTMLNQKGHEIPWPHKISCACLECTNGRQYDLLKFSLSRINTYRGIASRA 205 Query: 244 XXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQI 303 +D +L+AF LS +LR+LS E EFK +Y L CQEFA LL R +E+ Sbjct: 206 YLSITAEDAMLSAFRLSRDLRKLSKKEPEFKPQYLSLEQVCQEFAVELLGMCRNQSEVTT 265 Query: 304 LLNH--EKGASPQAPLTEPGAPERM-RLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESV 360 +LN ++ + L E + L+RL+LA+ QK+FVAHP QQ+L+SIW ++ Sbjct: 266 ILNSCGDRDEDSEDELDHQTFEEGIPNLARLRLAVNYNQKQFVAHPICQQVLSSIWCGNL 325 Query: 361 PGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLF 420 G+R + I P L Y AP S +G+ L+ P IKFL HSASY FL Sbjct: 326 SGWRGSRTSWKLLVSFGIFLTMPFLCLIYWIAPKSKLGKILKIPVIKFLLHSASYMWFLI 385 Query: 421 LLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGL 480 L+ S +E V + +R+ ++ + + WV G W E K++W GL Sbjct: 386 TLLGESIAME---------VYRESFATRQHTI--LHNSFHMVWVVGFFWFECKEVWIEGL 434 Query: 481 REYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQP---------REKWD 531 R Y D WN +D + S+Y+A+ ALR+V +V LQ NQ R++W Sbjct: 435 RSYFLDWWNCLDVMVLSMYLASFALRLVIMLKVH--FLCQLQDNQDECVYFTETMRDQWH 492 Query: 532 AWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFA 591 DP +SE LF+ ++ S +L YI + LG LQ+S+ +M+ D+++F + +++ A Sbjct: 493 QEDPQFISEVLFAVTSMLSFTRLAYILPAHESLGTLQISIGKMIDDMMRFMFILVIIGTA 552 Query: 592 FSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVD 651 F CG+N + Y ++PN +L ET LFW FG+ D Sbjct: 553 FLCGINNIYVPY------------IISPN-----------LGKLNETFSFLFWTMFGMAD 589 Query: 652 LDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARS 711 ++ + G +++G Y +S+Q I + ADVEWKFARS Sbjct: 590 QTYVDMPAFAL-AELVGRILYGIYTLIIVIVLLNMLIAMITNSFQKIEDDADVEWKFARS 648 Query: 712 KLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC 749 KL++SYF EG T P PFN++PSPK++ Y R + +R+C Sbjct: 649 KLYLSYFREGLTMPVPFNIIPSPKAVFYLLRGIVKRIC 686 >UniRef50_A7RSZ7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 523 Score = 275 bits (675), Expect = 3e-72 Identities = 176/564 (31%), Positives = 285/564 (50%), Gaps = 50/564 (8%) Query: 181 PLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXX 240 PL++AA +YE++ +L+ +G QL +PH+V C C++C + D+ R S+ R++ YR Sbjct: 1 PLVVAAQLGNYEVLNMLVSKGFQLVKPHNVLCRCEEC----QADNFRESQRRLDIYRGLA 56 Query: 241 XXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNE 300 DP LTAFELS EL ++ E E++ +Y +L QC +F LLD RTS E Sbjct: 57 NPVFISMTSNDPFLTAFELSSELEVIARREDEYEKDYLQLSQQCSQFTIGLLDECRTSRE 116 Query: 301 LQILLNH--EKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYE 358 + +LN+ E G+ E A + L + AI QK+FVAHP Q L+ + Sbjct: 117 QRCILNYPGENGS------VEDYAENSLGL--VNSAISYNQKEFVAHPFCQHLVMQHIFG 168 Query: 359 SVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMF 418 + G+R + L + A ++ +FP+ ++ Y P VGR +++PF+KF+ H++S+ +F Sbjct: 169 DITGWRTNHFLYRIAYVLTQVIIFPVLAVIYFFMPFLEVGRKIKRPFVKFINHTSSFVVF 228 Query: 419 LFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDM 478 L LL ++S H + R MPS +EWLI +W+ G+ WSE KQ+W Sbjct: 229 LILLAVSS---------------HHQFEIRFRKMPSGLEWLIFSWILGVAWSECKQVWHE 273 Query: 479 GLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPML- 537 G R Y WN +D L + L + + V + L A D +L Sbjct: 274 GARRYFSSGWNWMDIGMVFLLLGAFVLWTII-FIVDFDSNAKL----------AHDVLLS 322 Query: 538 LSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLN 597 ++G+++ + S +L+Y+ ++ +LG LQ+SLSRMV I +F + +V+++FS + Sbjct: 323 TADGMYAFGVVASFFRLIYLCQISRYLGLLQLSLSRMVRVIFQFAFISCVVLWSFSVAMT 382 Query: 598 QLLWYYADMEKKRCTVGTALTPNGTLPDPDACV--VWRRLFETMQTLFWAAFGLVDLDSF 655 L Y + E + D DA + + L TM TL WA+ +V LD+ Sbjct: 383 ML--YMSSFEAYQ----LPRPVKNVTSDIDAILDKGYDNLLSTMVTLMWASLDMVGLDTL 436 Query: 656 ELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWI 715 + + +FW +F Y +SYQ + + + E+KFAR++LW Sbjct: 437 NVFKKQSLIQFWTAALFTLYHAASMVVLLNMLIAMMSNSYQQVEDNIETEYKFARTQLWT 496 Query: 716 SYFEEG-GTAPPPFNVLPSPKSLL 738 Y + T PPP N+LP+PK ++ Sbjct: 497 DYIGDAVPTLPPPLNLLPTPKYIV 520 >UniRef50_UPI0000E4A5BA Cluster: PREDICTED: similar to transient receptor protein 5; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to transient receptor protein 5 - Strongylocentrotus purpuratus Length = 1007 Score = 261 bits (640), Expect = 6e-68 Identities = 162/455 (35%), Positives = 232/455 (50%), Gaps = 32/455 (7%) Query: 67 EKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXXXXXF 126 EK +L E+GD L A D +N++ D GRSAL++AI Sbjct: 14 EKLFLAAAEKGDKKAILYALDNAPD---LNINSSDKDGRSALVIAIQNGNSDIIVVLLEH 70 Query: 127 GVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLILAA 186 G++ DALL A+ E+F+ A + + +H ++ P E AL F DITP++LAA Sbjct: 71 GIQLGDALLRAVDEQFIYAAQIICEHIKQKNIP-EFLKCRAL---NGDFHPDITPIVLAA 126 Query: 187 HRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXXXXX 246 H ++Y+IIK+LL+ GA++ +P + S ++L+HS +N YR Sbjct: 127 HHNNYDIIKILLEYGARIEDP-------EYYAFSTETNTLQHSLGMLNIYRALASQAYIS 179 Query: 247 XXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQILLN 306 DPI T FE +LR+L + EF E+ L QC++FA +L H R E +L Sbjct: 180 LTSLDPINTGFERCVKLRKLCQINPEFSVEFNTLAGQCEQFAADILGHIRNQAEQTCVLY 239 Query: 307 HEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRK 366 H+ P + ++K+AI Q+KFVAHP+ QQ L +WYE +P + Sbjct: 240 HD-------PCFYSIGESGIGPYKVKIAIHHEQRKFVAHPHCQQHLTQLWYEGLPSWYMT 292 Query: 367 NMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILAS 426 N + IG FP+ L YI P +GR +R P ++F+CH +S M +FLL+L Sbjct: 293 NWISSTLSTSAIGFGFPILCLLYIIYPWGNIGRLMRVPHVQFVCHISS--MLVFLLLLGL 350 Query: 427 QRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHD 486 Q T D + +R +P EWLIL WV GL W E+K+LW G R Y+ D Sbjct: 351 QSSFTP------KYDDDPDVDQRAEVPKPTEWLILVWVIGLTWVEIKELWYYGSR-YLKD 403 Query: 487 MWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGL 521 WN++DF T SLY A +ALRIV + R MAM L Sbjct: 404 RWNILDFFTLSLYWAAIALRIVIYR--RHGMAMEL 436 Score = 190 bits (462), Expect = 2e-46 Identities = 116/323 (35%), Positives = 172/323 (53%), Gaps = 35/323 (10%) Query: 501 ATVALRIVSHYQVRREMAMGLQWNQPRE---KWDAWDPMLLSEGLFSAANIFSSLKLVYI 557 A VA +VS + ++ A G N R W A+DP+L+SEGLF+ A + S L+ + Sbjct: 538 AAVAAPVVSGGRRGKKAAAGTATNTTRTGRANWSAYDPLLISEGLFAIAKVLSFLRPICY 597 Query: 558 FSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTAL 617 +N H+GP+Q+SL M+ DI KF ++ V FAFS G+NQL YY+ ++ + Sbjct: 598 TVMNRHVGPMQISLGNMMFDICKFLLIFCFVWFAFSLGMNQLYGYYS-----MSSLNASF 652 Query: 618 TPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKI-FTRFWGMLMFGTYX 676 T G TM TLFWA FGL +++ ++ G+ FT G++++ Y Sbjct: 653 TDRGY---------------TMSTLFWALFGLPEMNIVDIRGVDHEFTETVGLMLYAAYH 697 Query: 677 XXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKS 736 ++Y I + ++V+WKF+RSKLW+SYF G+ P PFNVLP+PKS Sbjct: 698 VIAIVVLLNVLIAMMSNTYTRIEDDSEVQWKFSRSKLWMSYFAGRGSLPAPFNVLPTPKS 757 Query: 737 LLYAWRWLQRRLCGHA---------RAKREHM-RTIRAIMRNLVRRYVTVQQRRAESGGV 786 +LY +RWL+ +L +AK E + R IM LV+RY+ +R E Sbjct: 758 MLYLFRWLRGKLGSEKHRQEIRDRNKAKMEEKEQQYREIMGKLVKRYI-FDAKRDEDENN 816 Query: 787 TEDDVNEIKQDVSAFRCELVEIL 809 E VN +KQD+S F+ E+ E L Sbjct: 817 QEQWVNRLKQDISGFKYEMFEAL 839 >UniRef50_Q179M4 Cluster: Transient receptor potential channel 4, putative; n=2; Culicidae|Rep: Transient receptor potential channel 4, putative - Aedes aegypti (Yellowfever mosquito) Length = 776 Score = 256 bits (626), Expect = 3e-66 Identities = 133/293 (45%), Positives = 182/293 (62%), Gaps = 25/293 (8%) Query: 574 MVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPD----PDAC 629 MV+DI+KFF + LV+FAF+CGLNQLLWY+AD+EK +C + G LPD DAC Sbjct: 1 MVIDIVKFFFIYSLVLFAFACGLNQLLWYFADLEKSKC-----YSLKGGLPDWDNQGDAC 55 Query: 630 VVWRR---LFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXX 686 + WRR LFE+ Q+LFWA+FG+V L+SFEL GIK +TRFWG+LMFG+Y Sbjct: 56 MKWRRFGNLFESSQSLFWASFGMVGLESFELAGIKSYTRFWGLLMFGSYCVINVIVLLNL 115 Query: 687 XXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAW----- 741 +SY +I E +D EWKFAR++LW+SYFEE T PPPFN+ P+ K ++ Sbjct: 116 LIAMMSNSYAMIDEHSDTEWKFARTRLWMSYFEESSTLPPPFNIFPNMKHVMRLCGKKKK 175 Query: 742 RWLQRRLCGHARAKREHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAF 801 R ++R + +E +MR+LV RYV+ R+ E VTEDD+NE+K ++SA Sbjct: 176 RDIKRESTIRRKEDKERAERYTNVMRSLVWRYVSAMHRKMEENAVTEDDINEVKGEISAM 235 Query: 802 RCELVEILRNSGMNTSTANAGAPEVMMLRAGGGGGKKNRQKERRLMKGFNIAP 854 R EL+EI +GM+ S A+ V+ K+ + ERRLMK F++AP Sbjct: 236 RYELLEIFEKNGMDVSAADRKEKAVL--------AKRMKIWERRLMKDFHVAP 280 >UniRef50_UPI0000D55FE0 Cluster: PREDICTED: similar to transient receptor potential cation channel, subfamily C, member 4 isoform 2; n=1; Tribolium castaneum|Rep: PREDICTED: similar to transient receptor potential cation channel, subfamily C, member 4 isoform 2 - Tribolium castaneum Length = 779 Score = 251 bits (615), Expect = 6e-65 Identities = 204/785 (25%), Positives = 348/785 (44%), Gaps = 65/785 (8%) Query: 47 MTEEENVVRPHQEMAVLSLEE--KKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLG 104 + E++ ++ P + + L+E K++ V GDVA L + N++CV+ G Sbjct: 35 LEEDDELLMPRPSILLPHLQESEKRFFELVHSGDVAAVNDFLN---ENPGFNINCVNFQG 91 Query: 105 RSALLMAIDXXXXXXXXXXXXF-GVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPN 163 S LL+A+ ++ D +LHAI + + +E LL+ + T P+ Sbjct: 92 VSGLLIAVQSRSEAMVEFLLSQPDIDIGDCVLHAIRDNQPKILELLLEKQRNTA----PS 147 Query: 164 SWEALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHD--------VR---- 211 ++ F +TPLILAA YEII++L+DRG + +PH VR Sbjct: 148 LEYVGVTHSSDFPDYVTPLILAAQCGHYEIIEMLIDRGHTISKPHSPSCRSVPKVRYGHC 207 Query: 212 CGCDDCVRSRREDSLRHSRS-RINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALE 270 C C DC D L H+ R+N Y+ +DPILT+F+LS ELR+ S L Sbjct: 208 CRCMDCKAQLERDDLLHAEHLRLNLYKSVCNPAYICHSSRDPILTSFQLSTELRQCSFLV 267 Query: 271 HEFKTEYQELRVQCQEFATALLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSR 330 EF+ Y EL + FA L+ R S E++ +L + G + P R Sbjct: 268 PEFRNSYLELANEVSNFAVELIAGCRNSGEVETILKQKAGIQNASIFMYP---------R 318 Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYI 390 L LA+ +QK FVAH +VQ ++ S+W + + K + + + + P+ + I Sbjct: 319 LVLAMDYKQKFFVAHAHVQHIVESLWRGNWYDYNLKPIPAKIIYPIFRILLLPIIVVMCI 378 Query: 391 AAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRG 450 P + P + + H A++ +FL ++ L S R + +R Sbjct: 379 FLPKHQMVAHWNIPLNRMINHVAAFLVFLVIIFLESNR--------------SKENQKRM 424 Query: 451 SMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSH 510 S +E +I+ +V WS V+ G R Y +WN ++N+ +V T + S+ Sbjct: 425 PPNSGLEPVIIIFVVANCWSVVRMCLIQGPRRYFTYLWNWHAVISNTFFVLTFVFWLASY 484 Query: 511 YQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVS 570 + L+ R+ W DP+L++EG F+ A I + KL++ +N +LGPLQ+S Sbjct: 485 VDAVNNDQVDLE----RKYWHHLDPVLIAEGTFAVAVIMTYFKLMFFCRLNYYLGPLQIS 540 Query: 571 LSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEK------KRCTVGTALTPNGTLP 624 L +M D+ K+ + I++I +F+ GL + YY M + K V + + + TL Sbjct: 541 LGKMCSDMAKYITIFIIIIISFTAGLCRFYSYYDGMVQVDSNGIKTAQVSSFIDFSTTLK 600 Query: 625 DPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXX 684 V ET + G D ++ + +FT G + F + Sbjct: 601 TFFWAVFCMAPLETGDVIIENLPG--DTENTTIINKHLFTEAVGYIAFALFEVLTVVMIL 658 Query: 685 XXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWL 744 ++Q + + DVEW F ++ ++ Y + T PPP N++P+P + W Sbjct: 659 NMLIATMSSTFQRVLDNIDVEWTFGKTDFYLEYMLQ-PTLPPPLNLIPTPSGISAFMEWF 717 Query: 745 QRRLCGHARAKREHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCE 804 Q + E A+M LV+RY R +S E+D+ +KQ+++ + Sbjct: 718 QSPKVD--PREEEKRNDYPALMSQLVQRYF----RDKDSAASPENDLEFLKQEIAEIKQA 771 Query: 805 LVEIL 809 + ++L Sbjct: 772 VNDLL 776 >UniRef50_A7RJX1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 589 Score = 250 bits (611), Expect = 2e-64 Identities = 182/618 (29%), Positives = 296/618 (47%), Gaps = 48/618 (7%) Query: 127 GVETRDALLHAISEEFVEAVEALLDHEERT-RKPGEPNSWEALPPETATFTSDITPLILA 185 G + ALL A+S++ V V+ALL +E R +S L T +TPLILA Sbjct: 11 GADVGAALLQAVSKDNVLYVKALLAYENNNDRFSRRSSSCVNLSKNTNDSNRYMTPLILA 70 Query: 186 AHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXXXX 245 +H +SY+I+KLLL +G + HD C C C R + H A Sbjct: 71 SHNNSYDIVKLLLSKGHTIDRVHDRGCLCPWCQSLGRIGTSLHRLYTYRALASPVYMSLT 130 Query: 246 XXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQILL 305 KDP+ AFEL+ EL L+ +E+EF+++Y +L QC+EFA ALLD R +E++ ++ Sbjct: 131 FLSCKDPVRQAFELNKELVELADIEYEFRSDYLQLSQQCEEFAVALLDQCRDMSEIEQMM 190 Query: 306 NHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRR 365 + LT+ G+ L L AI + +FVAHP Q +L S+ Y + + Sbjct: 191 S---VPDMDGALTKNGSKS---LGVLDYAINNKNGRFVAHPYCQMMLNSVIYGDFHTWEK 244 Query: 366 KNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILA 425 + L+ + P++++ Y P S + + L P +KF+ H+ ++ +FL LLIL+ Sbjct: 245 MGVTLKILFALLFTIFIPVWAIVYFFTPTSCLSQKLATPILKFIMHTGAFGLFLLLLILS 304 Query: 426 S-QRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYV 484 S QR ++ LL + + + LI W+ GLI E+K +W G Y+ Sbjct: 305 SIQRFISSNTFLL------------KFLFNFSDILITIWIFGLIVQELKDMWRQGKERYL 352 Query: 485 HDMWNVIDFVTNSLYVATVALRIV-SHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLF 543 WN++ L++ + L + S V +E ++ +++ +LL+ F Sbjct: 353 SQWWNLVTLAMLGLFIISGILWVAGSALSVSKEGSLA----------ESYRFILLANAFF 402 Query: 544 SAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYY 603 + + + L VN LGPLQ+SL +MV DILKF +L L+ AF L ++ Y Sbjct: 403 TIGVLLAFLHFSNAVQVNSTLGPLQLSLVKMVKDILKFLLLFFLIYLAFVVALRRVYSQY 462 Query: 604 ADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELD---GI 660 V TP+ T+ V+ + +M+ +FWA F +L+ F D Sbjct: 463 ---------VWAGKTPH-TI---SLYSVFCSVQGSMRLVFWAIFDKTELEEFNTDPSFPT 509 Query: 661 KIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEE 720 KI T+ G ++F + +S+Q +++ D WKF+R+++W+ Y + Sbjct: 510 KI-TQSTGEVLFALFNIASILVAINMLIAMMSNSFQKVADSEDFLWKFSRTRMWMEYIIK 568 Query: 721 GGTAPPPFNVLPSPKSLL 738 G P PF+VLPS S++ Sbjct: 569 GSVLPAPFSVLPSIASII 586 >UniRef50_Q4S8W5 Cluster: Chromosome 7 SCAF14703, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7 SCAF14703, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 689 Score = 230 bits (563), Expect = 1e-58 Identities = 181/619 (29%), Positives = 280/619 (45%), Gaps = 62/619 (10%) Query: 129 ETRDALLHAISEEFVEAVEALLDH--EERTRKPGEPNSWEAL---PPETATFTSDITPLI 183 + +ALL A+ V+ LLD +E+ K + +A+ + + F +TPL Sbjct: 24 QIHEALLVAVDTNQPRVVKRLLDRLDQEKGNKMDVRSFSQAIFDHSIDNSQFAPGVTPLT 83 Query: 184 LAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXX 243 LA +D Y+I+ +L +G +P PH + C C +C R+ D L+ S SRIN YR Sbjct: 84 LACQKDLYDIVTMLTQKGHIIPWPHKISCACLECRNGRQYDLLKFSLSRINTYRGIASRA 143 Query: 244 XXXXXXKDPILTAFELSWELR----------------------RLSALEHEFKT------ 275 DP+L AF LS ELR RLS + + + Sbjct: 144 YLSITSDDPMLKAFGLSRELRKLSQKEPEFKVRYRVSDFCLSNRLSCVLNRLRRPPLVQP 203 Query: 276 EYQELRVQCQEFATALLDHTRTSNELQILLNH---EKGASPQAPLTEPGAPERMRLSRLK 332 +Y L CQ++A LL R +E+ +LN E S + E G P LSRL+ Sbjct: 204 QYLSLEQLCQDYAVELLGMCRNQSEVTTILNSCGDESQDSFEGQAFEEGIPS---LSRLR 260 Query: 333 LAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAA 392 LA+ QK+FVAHP QQ+L+SIW ++ G+R + V I PL L Y A Sbjct: 261 LAVNYNQKQFVAHPICQQVLSSIWCGNLAGWRGSRTAWKLFVSVGIFLTMPLLCLIYWIA 320 Query: 393 PHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSM 452 P S G+ L+ P IKFL HSASY FL L+ S ++ ++ D+ SR+ + Sbjct: 321 PKSKAGKILKIPVIKFLLHSASYLWFLIALLGES---------IMMELYRDKFASRQQDI 371 Query: 453 PSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIV---S 509 + + WV G W E K++W GLR Y D WN +D + S+Y+A+ ALR++ Sbjct: 372 --LHSSFHMVWVVGFFWYECKEVWIEGLRSYFLDWWNCLDVMVLSMYLASFALRVLIMLK 429 Query: 510 HYQVRREMAMGLQW----NQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLG 565 Y + ++ + + RE W DP L+SE LF+ ++ S +L YI + LG Sbjct: 430 GYFLCQDHSGTEECVYFTETVRENWHQEDPQLISEVLFAVTSMLSFTRLAYILPAHESLG 489 Query: 566 PLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALT--PNGTL 623 LQ+S+ +M+ D++++ + + C L + + +GTA N Sbjct: 490 TLQISIGKMIDDMMRWEQFQL--SSSGRCWLKLIKASFFRFMFILMIIGTAFLCGINNIY 547 Query: 624 PDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXX 683 R ET LFW FG+ + D ++ + F G +++G + Sbjct: 548 VPYVISPHLGRFNETFHFLFWTMFGVANQDYVDMPQF-VLAEFVGRILYGIFTLVIVIVL 606 Query: 684 XXXXXXXXXHSYQLISERA 702 +S+Q I R+ Sbjct: 607 LNMLIAMITNSFQKIEVRS 625 >UniRef50_Q70T25 Cluster: Transient receptor potential channel 7; n=22; Euteleostomi|Rep: Transient receptor potential channel 7 - Homo sapiens (Human) Length = 807 Score = 215 bits (526), Expect = 4e-54 Identities = 137/366 (37%), Positives = 192/366 (52%), Gaps = 45/366 (12%) Query: 397 VGRTLRKPFIKFLCHSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGS 451 +GRTLR PF+KF+ H+ S+ +FL LL++ AS R E T P D + + + R + + Sbjct: 322 LGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTD--YPKQIFRVKTT 379 Query: 452 MPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVS-- 509 S E LI+ WV G+IWSE K++W+ G REYV +WN++DF S++VA+ R ++ Sbjct: 380 QFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFL 439 Query: 510 -----------HYQVRREMAMGLQ-----WNQPREKWDAWDPMLLSEGLFSAANIFSSLK 553 H Q + L + R+KW DP ++SEGL++ A + S + Sbjct: 440 KATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSR 499 Query: 554 LVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTV 613 + YI N GPLQ+SL R V DI KF V+ I+V AF G+ L YY Sbjct: 500 IAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYR--------- 550 Query: 614 GTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFG 673 G P T + E+ +TLFW+ FGL ++ S L F G +++G Sbjct: 551 GAKYNPAFTTVE-----------ESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYG 599 Query: 674 TYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPS 733 Y +SYQ I E ADVEWKFAR+KLW+SYF+EG T P PFN++PS Sbjct: 600 VYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPS 659 Query: 734 PKSLLY 739 PKS Y Sbjct: 660 PKSFYY 665 Score = 177 bits (431), Expect = 1e-42 Identities = 106/291 (36%), Positives = 163/291 (56%), Gaps = 21/291 (7%) Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122 L+ EE+++L E G++ R++L+ ++ +N +CVD +G++AL +A+ Sbjct: 40 LTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVTEL 96 Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170 R DALL AIS+ +V VEA+L+H + T P E + + A Sbjct: 97 LLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDE 156 Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230 + F+ DITP+ILAAH YEI+ +LL +GA++ PHD C C++C +R+DS HSR Sbjct: 157 DGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSR 216 Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290 SR+NAY+ +DP+LTA ELS EL RL+ +E EFK +Y++L +QC++F Sbjct: 217 SRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVG 276 Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKK 341 +LD R + E++ +LN + + P LSR+KLAIK KK Sbjct: 277 VLDLCRDTEEVEAILNGDVNFQVWSDHHRPS------LSRIKLAIKYEVKK 321 Score = 42.7 bits (96), Expect = 0.049 Identities = 20/43 (46%), Positives = 29/43 (67%) Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807 IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E Sbjct: 728 IMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLE 770 >UniRef50_UPI0000E4A874 Cluster: PREDICTED: hypothetical protein, partial; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein, partial - Strongylocentrotus purpuratus Length = 348 Score = 198 bits (482), Expect = 8e-49 Identities = 114/344 (33%), Positives = 180/344 (52%), Gaps = 18/344 (5%) Query: 175 FTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRIN 234 F D++PL+LAA ++++ IK LL+ GA++ +P + + +L +S +N Sbjct: 17 FHPDVSPLVLAAQHNNFDTIKTLLEAGARIKDPREN-------LDQSEVHTLENSVGMLN 69 Query: 235 AYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDH 294 Y+ DP T FEL ++R+L ++EF ++QEL QC++FA LLD Sbjct: 70 LYKALASQSYISLTSSDPFNTTFELCAKMRKLMRTKYEFCDQFQELADQCEQFAADLLDQ 129 Query: 295 TRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLAS 354 R S E +LNH+ P + A + +R+K AI Q+KFVAHP+ QQ L Sbjct: 130 VRDSGEQAYILNHDSYGWGN-PNSNSAAEQP---NRVKAAIHFEQRKFVAHPHCQQRLIE 185 Query: 355 IWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSAS 414 WY +PG+R + L + +G FPL S+AYI P L P++KF+CH++S Sbjct: 186 RWYAGLPGWRDMSSLRSGFLVFLMGLGFPLLSIAYIIYPRGRYRDFLSIPYVKFVCHTSS 245 Query: 415 YFMFLFLLI---LASQRIETAPGGLL---WDVSHDEPLSRRGSMPSIVEWLILAWVSGLI 468 FL LL+ +A ++ T + + + R P+I LI+AWV+G Sbjct: 246 MIYFLLLLLYQTMAENQVRTETDTMTDGNGTTTATRAIDSRSDPPTITMLLIVAWVAGQT 305 Query: 469 WSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQ 512 W + K+LW G R +V ++WN DF SL+ + +ALR++ + Q Sbjct: 306 WQKCKELWYNGARFFV-NLWNYFDFFMLSLFWSFIALRVMVYIQ 348 >UniRef50_UPI0000E46FC6 Cluster: PREDICTED: similar to transient receptor potential cation channel, subfamily C, member 5; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to transient receptor potential cation channel, subfamily C, member 5 - Strongylocentrotus purpuratus Length = 1025 Score = 192 bits (469), Expect = 3e-47 Identities = 140/459 (30%), Positives = 228/459 (49%), Gaps = 28/459 (6%) Query: 58 QEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXX 117 ++M+ + EE+ ++ V GDV+ L + T ++V+C D GR+A+ +AI Sbjct: 108 EDMSAFTHEER-FMAAVRDGDVSFVEDALDKLA-TQPLDVNCTDRNGRTAIAVAITRGNL 165 Query: 118 XXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALP--PETATF 175 V D+LL A+ +F+EAV+ +L H E G+ N E + ET + Sbjct: 166 LILKLLLKSNVAIGDSLLRAVDTQFLEAVKLILKHSESC---GD-NQMEIVNCRSETDDY 221 Query: 176 TSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINA 235 +ITP+ILA H +++EII +LL A +P P D R+ + +L+ S +N Sbjct: 222 HPEITPIILACHHNNFEIIDILLKYKALVPSPDS-----SDSERTAKH-TLQRSVGTLNI 275 Query: 236 YRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHT 295 YR DP+ F L LR +S LE+EF+ EY EL +E+A LL Sbjct: 276 YRALSSQFYISKVSDDPMGDGFLLCNRLREMSGLEYEFRAEYLELADTMEEYAADLLGQA 335 Query: 296 RTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASI 355 R S EL ++ H P+ + G + L ++ +AI QKKFVAHP+ QQLL Sbjct: 336 RDSKELNKIMTH----GPKKNKSGDGDDGAI-LQKVFMAIDYTQKKFVAHPHCQQLLIKR 390 Query: 356 WYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASY 415 ++ S+ R + Q + I +P S+ YI P V PF+KFL S Sbjct: 391 FFGSLAYTRDWPLWKQLLMSLVIMVGYPFISIVYILVPTQKVITFGDTPFVKFLMSVGSR 450 Query: 416 FMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQL 475 FL L++A+ +A G + D+PL + +P + +LILAW+ G+ W+ +K + Sbjct: 451 LTFLVFLLIAT----SASG-----TTSDDPLKQWTRIPVPLLFLILAWLIGMTWAAIKDI 501 Query: 476 WDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVR 514 + G++ +V + NV++F +L+ + L ++++ Q R Sbjct: 502 YRQGVKTFVTNGQNVLEFFILALFWPALILYLMAYLQTR 540 Score = 142 bits (345), Expect = 3e-32 Identities = 91/290 (31%), Positives = 147/290 (50%), Gaps = 20/290 (6%) Query: 535 PMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSC 594 P +L++ F+ A + + L+L+ + + +GPLQ+SL M+ DI+KF ++ I+V FAF+ Sbjct: 631 PSVLADAFFAIATVIAFLRLLSLTVSSQLVGPLQISLGGMLFDIVKFILVFIIVWFAFAL 690 Query: 595 GLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDS 654 GLNQ+ Y + + C PN D A + + +M TLFWA FGL L Sbjct: 691 GLNQIYQTYEEHTYQECMTD----PNAAC-DSGA---FSSVGLSMLTLFWALFGLESLSI 742 Query: 655 FELD-GIK-IFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712 +L+ GI FT G L+FG Y ++Y + E +D EWK+AR++ Sbjct: 743 IQLESGINHYFTEAVGTLLFGLYLMFAVVVMLNALIAMMSNTYTRVEENSDTEWKYARAQ 802 Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-------GHARAKREH-MRTIRA 764 +W+S+ + G T PPPFNV P+ + + + C + + +R+ + Sbjct: 803 MWVSFLQHGNTTPPPFNVFPAIRDWALMCKNIGSSCCFSRKDVNDNTKKRRDKGQQEYTV 862 Query: 765 IMRNLVRRYVTVQQR-RAES-GGVTEDDVNEIKQDVSAFRCELVEILRNS 812 +R LV RY+ Q A+S VT D+ I+ D++ FR E + L+ S Sbjct: 863 TVRQLVERYILDQTTLGADSEANVTRSDIMAIRNDIAVFRYETFKSLKAS 912 >UniRef50_UPI0000E46001 Cluster: PREDICTED: similar to transient receptor potential channel 6, variant delta377-431; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to transient receptor potential channel 6, variant delta377-431 - Strongylocentrotus purpuratus Length = 827 Score = 190 bits (463), Expect = 2e-46 Identities = 150/520 (28%), Positives = 239/520 (45%), Gaps = 89/520 (17%) Query: 398 GRTLRKPFIKFLCHSASYFMFLFLLILAS--------QRIETAPGGLLWDVSHDEP-LSR 448 G +R P IKF+ S Y +FL L+ + S +R + + + P + + Sbjct: 301 GNFMRSPIIKFINQSVMYLVFLLLMFMESVMESSGIFRRNDITIESIFQSSNSCRPYIDQ 360 Query: 449 RGSM----------PSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSL 498 GS SI+E+++ +V G+IW EVKQ+W G+ YV +WN ID +L Sbjct: 361 IGSYHNIKANIREASSIIEFILFIFVMGMIWQEVKQIWREGVHTYVRSIWNWIDLAMLNL 420 Query: 499 YVATVALRIVS---------HYQ--------VRREMAMGLQW---NQPREKWDAWDPMLL 538 ++++ + ++ +Q + E Q+ + R W+ DP L+ Sbjct: 421 LLSSLVIVFMTTELTNKAEQFFQTEGNCKALINNEAKAQRQFYFLSGDRRAWENNDPNLI 480 Query: 539 SEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQ 598 EGLF+ AN+ S +L +I V+ LGPLQ+SL RM+ DI++F + +V AF C + Sbjct: 481 GEGLFAMANVLSFSRLSFILPVSEFLGPLQISLGRMMGDIMRFAAMFTVVFIAFLCAMCN 540 Query: 599 LLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSF--- 655 L WYY PN + + L ++TL WA FGL D Sbjct: 541 LYWYY---------------PNES--------AFGSLLNAIRTLMWALFGLGDPSDLSCP 577 Query: 656 --ELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKL 713 + D T +G+L++ +Y S+ I+ DVEWKF+RSKL Sbjct: 578 DTDSDCGHTSTEAFGILLYSSYMGIMVIVMLNMLIAMMSSSFDAINNDEDVEWKFSRSKL 637 Query: 714 WISYFEEGGTAPPPFNVLPSPKSL----------LYAWRWLQRRLCGH--------ARAK 755 W+SYFE+G T P PFN++PSPKS+ L QR + H RA Sbjct: 638 WLSYFEKGATLPVPFNLIPSPKSIFNNIIVAGYQLIKKNSRQRNIATHRITSQSNLRRAL 697 Query: 756 REHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVEILRNSGMN 815 R ++ + +M+N+V+R++ QR ++ V E ++ EIK D+S+FR +++ +L N Sbjct: 698 RRNVTSHDDLMKNVVKRFLFKLQRSKDTDEVDEGELEEIKNDISSFRFDVLGMLGNLSSK 757 Query: 816 TST---ANAGAPEVMMLRAGGGGGKKNRQKE-RRLMKGFN 851 N+ + GG GK N + ++ G N Sbjct: 758 VDAQKPGNSNMSNGYQEQGQGGLGKTNNLDDLEKVADGIN 797 Score = 129 bits (311), Expect = 4e-28 Identities = 80/227 (35%), Positives = 124/227 (54%), Gaps = 14/227 (6%) Query: 129 ETRDALLHAISEEFVEAVEALLDH----EERTRKPGEPNSWEALPPET--ATFTSDITPL 182 E ++L+ AI++ +V + LL H E++ R E + + F D+TP+ Sbjct: 75 EIHESLMVAITKGYVNITQVLLGHPCYDEKKNRAMQTLGPHETFYDRSYRSKFDRDVTPI 134 Query: 183 ILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXX 242 ++AA + +I+++L+DRG + +PH CGC C+ + D L HS S INAYR Sbjct: 135 MMAAMYNEVDILRILMDRGDDVVKPHHPLCGCTTCLNRKEYDPLMHSLSIINAYRALCSE 194 Query: 243 XXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQ 302 +DPILTAF LS EL L E EFKTEY+EL+ +C+ +A+ LLD + + E++ Sbjct: 195 AYISLTSEDPILTAFLLSKELDGLCRTEKEFKTEYKELKQKCKMYASNLLDMCQNTEEVK 254 Query: 303 ILLNH----EKGASPQA---PLTEPGAPERMRLSRLKLAIKLRQKKF 342 +L E QA PL E ++ L RL++AI+ +QK+F Sbjct: 255 TILKQAAISETEVKEQACHNPL-ENDKEDQNALPRLEMAIEYQQKQF 300 >UniRef50_Q6L6S5 Cluster: Transient receptor potential cation channel TRPC3; n=11; Tetrapoda|Rep: Transient receptor potential cation channel TRPC3 - Bos taurus (Bovine) Length = 357 Score = 178 bits (434), Expect = 5e-43 Identities = 120/379 (31%), Positives = 188/379 (49%), Gaps = 45/379 (11%) Query: 349 QQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKF 408 QQ L +IWYE++ G R + + ++ ++ + P ++ Y AP S +G+ LR PF+KF Sbjct: 1 QQQLLTIWYENLSGLREQTVAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKVLRSPFMKF 60 Query: 409 LCHSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGSMPSIVEWLILAW 463 + H+AS+ +FL LL+ AS R E T P + + + + + R + + + E LI+ W Sbjct: 61 VAHAASFIIFLGLLVFNASDRFEGITTLPN--ITVIDYPKQIFRVKTTQFTWTEMLIMVW 118 Query: 464 VSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR-------- 515 V G++WSE K+LW G REY+ +WNV+DF S+++A R ++ Q + Sbjct: 119 VLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSY 178 Query: 516 -------EMAMGLQ---WNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLG 565 E+ + + + R+KW DP ++SEGL++ A + S ++ YI N G Sbjct: 179 VQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFG 238 Query: 566 PLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPD 625 PLQ+SL R V DI KF VL I+V AF G+ L YY + V A T Sbjct: 239 PLQISLGRTVKDIFKFMVLFIMVFLAFMIGMFILYSYYLGAK-----VNAAFT------- 286 Query: 626 PDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXX 685 + E+ +TLFW+ FGL ++ S L F G +++G Y Sbjct: 287 --------TVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLN 338 Query: 686 XXXXXXXHSYQLISERADV 704 SYQ I + +DV Sbjct: 339 MLIAMINSSYQEIEDDSDV 357 >UniRef50_A7RH68 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 571 Score = 152 bits (368), Expect = 5e-35 Identities = 122/457 (26%), Positives = 203/457 (44%), Gaps = 43/457 (9%) Query: 170 PETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRRED---SL 226 PE + ++PL+LA H + ++II+L L +G ++ EPHD DD + R + L Sbjct: 113 PEDVKPGAFVSPLMLAVHLEKFDIIELFLSKGYRVLEPHDDDDEDDDDEQLNRTNVGLEL 172 Query: 227 RHSRS---RINAYRXXXXXXXXXXX------XKDPILTAFELSWELRRLSALEHEFKTEY 277 S R+NAYR PI EL+ +L+ + EF +Y Sbjct: 173 SSELSFNLRVNAYRALASPLYISYFFIMNPDALHPIFHVLELNKKLKNQMYRDFEFNNDY 232 Query: 278 QELRVQCQEFATALLDHTRTSNELQILLN----HEKGASPQAPLTEPGAPERMRLSRLKL 333 +++ CQ FA LL+ RT++E +LL+ ++ E LS L L Sbjct: 233 KQISKDCQRFAVDLLEQCRTTDETNVLLDVYPEIQRVYEKDKKHIEGSHTAFKELSMLNL 292 Query: 334 AIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAE-------MVRIGAMFPLYS 386 AI+ + VAHP Q L I Y + F+R+ + + +R + P + Sbjct: 293 AIRNDMNELVAHPQSQLRLDKILYHGLYMFKREPRVWRYRSWYTGKLFWLRHTLLLPFLA 352 Query: 387 LAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPL 446 L YI AP + L+ P +KF H+ ++ +F L ++ S ++ Sbjct: 353 LFYIIAPDCRISNVLKTPMVKFYSHTGAFVLFAIALAVS---------------SFEDHF 397 Query: 447 SRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALR 506 + +P +++W L +V GL EVK L+ G Y+ WN+I + L++ + +LR Sbjct: 398 TDYTLIPVLIDWGTLLFVLGLFLQEVKDLYFQGAFRYIRQWWNIISLLMVVLFLISYSLR 457 Query: 507 IVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGP 566 + + Y + L+ R LL+ F+ A +FS + L V+ GP Sbjct: 458 LTA-YLSPQTSPPHLKNLAVRSS----QLSLLANSFFAFAMVFSFIHLTNFLQVSDVFGP 512 Query: 567 LQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYY 603 LQ+SL + D++KFFV ++ AF L +L +Y Sbjct: 513 LQLSLYMLFADLIKFFVFFFVLFLAFGLSLRKLYSHY 549 >UniRef50_UPI0000F2E5D0 Cluster: PREDICTED: similar to capacitative calcium entry channel 2; n=1; Monodelphis domestica|Rep: PREDICTED: similar to capacitative calcium entry channel 2 - Monodelphis domestica Length = 378 Score = 111 bits (267), Expect = 9e-23 Identities = 60/164 (36%), Positives = 93/164 (56%), Gaps = 21/164 (12%) Query: 700 ERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC---------G 750 + AD+EWKFAR+KLW+SYF+EG T PPPFN++PSPKS Y W R + Sbjct: 8 DHADIEWKFARTKLWMSYFDEGATLPPPFNIIPSPKSFWYLGHWFHRHIYPKRDSADGRK 67 Query: 751 HARAK---REHMRTI------RAIMRNLVRRYVTVQQRRAESG-GVTEDDVNEIKQDVSA 800 H K H ++ + ++RNLV+RYV R +++ G+TE++ E+KQD+S+ Sbjct: 68 HGNLKTFTERHADSLIQNQNYQEVIRNLVKRYVAAMIRSSKTNEGLTEENFKELKQDISS 127 Query: 801 FRCELVEILRNSGMNTSTANAGAPEVMML--RAGGGGGKKNRQK 842 FR E++++L N + + + E+ G GG+K + K Sbjct: 128 FRYEVLDLLGNRKPQRRSFSTSSTEISQKDDANDGSGGEKAKSK 171 >UniRef50_UPI0000E46FC8 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 314 Score = 104 bits (250), Expect = 1e-20 Identities = 60/175 (34%), Positives = 88/175 (50%), Gaps = 8/175 (4%) Query: 635 LFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHS 694 L +M +L+W+ FGL+D DS + R G L++G + + Sbjct: 5 LGRSMMSLYWSLFGLIDRDSLNIKATPDVIRGAGELLYGAFYIFAVLVLLNALIAVMSNV 64 Query: 695 YQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWR-WLQRRLCGHAR 753 + + E ADVEWKFAR+ LW+S+ + T PPPFN+LP L + W Q +C R Sbjct: 65 FNKVEENADVEWKFARTTLWMSFLNDTVTVPPPFNLLPDCSQLKQRLKLWWQ--MCRRRR 122 Query: 754 -AKREHMRTIRAIMRNLVRRYV---TVQQRRAESGGVTEDDVNEIKQDVSAFRCE 804 + E +R IMR LV R+V T Q+ A+ GG+T D+ ++ DV R E Sbjct: 123 NIQTEVLRDSLRIMRRLVERFVAERTAQEANAQ-GGITVADIRNLRNDVVGLRYE 176 >UniRef50_UPI0000E46CF0 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 545 Score = 95.5 bits (227), Expect = 7e-18 Identities = 89/355 (25%), Positives = 146/355 (41%), Gaps = 27/355 (7%) Query: 60 MAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXX 119 MA + L +K +E D+ + +L R D G ++ D D GRS AI+ Sbjct: 1 MAFVKLHRQKLFETIESLDLFLVKTLLSRPDDFG-LDWDYRDKDGRSVYAHAINIGVTQM 59 Query: 120 XXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDI 179 G+ DALL A V+ V + + E K E + E + + Sbjct: 60 VVTFLDHGIPLGDALLRAADFCLVDIVRCICTYAETLSK-NERQAIIECHCENDDYHKVM 118 Query: 180 TPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXX 239 TPL+ A H++++ I+KLLL GA L EP + E L + + YR Sbjct: 119 TPLMAAGHKNNFAIVKLLLHAGAVLKEPK----------IKQDEADLTSTAIVLMTYRAI 168 Query: 240 XXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSN 299 DP+ AF L LR L+ + E + + ++FA + S+ Sbjct: 169 ATDAYLVQAFSDPLDAAFGLGRRLRELADRWEDVSEEVLRILDRVEQFAAGFVGQANYSS 228 Query: 300 ELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYES 359 E++ +L + S + +++++ A+K QK FV HP Q +L+ +YE Sbjct: 229 EVRTILKFTESES------------KHPVAKIRAAMKANQKPFVIHPFTQSILSDSYYEE 276 Query: 360 VPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSAS 414 + G K+ + + +PL SL Y+ P + R L+ P IK + S Sbjct: 277 LQG---KSAAMSFIFTLLAIFCYPLLSLCYLIYPAKPLHRFLKIPNIKLYINGGS 328 >UniRef50_A7SYW3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1148 Score = 95.1 bits (226), Expect = 9e-18 Identities = 79/294 (26%), Positives = 134/294 (45%), Gaps = 25/294 (8%) Query: 446 LSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVAL 505 LS P+ VE++IL + G I +EV+Q + Y DMWN +D Y+ V + Sbjct: 477 LSPSSVQPTAVEYVILVFFLGRILAEVQQYQRSRSKIYFRDMWNYLDITIILCYITIVIV 536 Query: 506 RIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLG 565 RIV+ MA + P + + ++ G+ + +F L++ + +N G Sbjct: 537 RIVT-------MAK----SGPVQGNNLLAGVMYMYGINT---LFLILRVSSVLELNRTTG 582 Query: 566 PLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLP- 624 PLQ++L RM++D+ V ++VI AFS + ++ Y+A T T +G P Sbjct: 583 PLQLALMRMLVDLWVIIVQFVVVILAFSFAITKV--YFAQRSLAMGQTETNATYSGFCPL 640 Query: 625 DPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXX 684 D C L +T ++L W+ FGL DLDS + T + ++ + Sbjct: 641 DGGNC-----LRKTTESLVWSLFGLTDLDSIATNNRAASTLAY--YLYAIFLVICVVMLL 693 Query: 685 XXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLL 738 ++Y+ I +D EWK+ R+ ++ + PPP N++ P SLL Sbjct: 694 NTLVALLNNTYEDIKSNSDTEWKYVRA-MYADQYNRCHPFPPPVNLITVPLSLL 746 >UniRef50_UPI0000F20B7A Cluster: PREDICTED: similar to CG5284-PA,; n=1; Danio rerio|Rep: PREDICTED: similar to CG5284-PA, - Danio rerio Length = 734 Score = 89.0 bits (211), Expect = 6e-16 Identities = 50/143 (34%), Positives = 76/143 (53%), Gaps = 12/143 (8%) Query: 461 LAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMG 520 + WV G W E K++W GLR Y D WN +D + S+Y+A+ ALR+V +V Sbjct: 35 MVWVVGFFWFECKEVWIEGLRSYFLDWWNCLDVMVLSMYLASFALRLVIMLKV--HFLCQ 92 Query: 521 LQWNQP---------REKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSL 571 LQ NQ R++W DP +SE LF+ ++ S +L YI + LG LQ+S+ Sbjct: 93 LQDNQDECVYFTETMRDQWHQEDPQFISEVLFAVTSMLSFTRLAYILPAHESLGTLQISI 152 Query: 572 SRMVLDILKFFVLDILVIFAFSC 594 +M+ D+++ V I F+C Sbjct: 153 GKMIDDMMRGIVKRICCC-CFNC 174 >UniRef50_Q21070 Cluster: Putative uncharacterized protein spe-41; n=2; Caenorhabditis|Rep: Putative uncharacterized protein spe-41 - Caenorhabditis elegans Length = 854 Score = 87.8 bits (208), Expect = 1e-15 Identities = 116/573 (20%), Positives = 229/573 (39%), Gaps = 58/573 (10%) Query: 175 FTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR-I 233 F +TPL+LA +++ I++ L+ RG + PH + C C C +RE HS +R + Sbjct: 140 FPPHMTPLMLACILNNFSIVQCLITRGHCIQIPHFITCECKTC---KRETVTTHSSTRLV 196 Query: 234 NAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEH-EFKTEYQELRVQCQEFATALL 292 + R D ++ +L++L++ + E+ Y++L + Q F + Sbjct: 197 DVMRALSSEAYLWLATDDVFAATCAVARDLQQLASDDQLEYVETYRDLEMNVQRFLCRIS 256 Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352 D +E +++ + + P+ +TE +P RL++A+ + ++F N Q + Sbjct: 257 DQAWRVDEFNMMVAN-RNYCPER-MTEISSP------RLQMAMDSQMRQFTCSTNSQTTI 308 Query: 353 ASI----WYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKF 408 S+ WY G + K A +R + P + + P G T+ P +F Sbjct: 309 KSVFRSDWYNY--GIKPKR---DAWRFLRACILMPFLVMLHAFMP--TKGTTMCVPLARF 361 Query: 409 LCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLI 468 + H Y +FL IL T W S + + +E + A+V GL Sbjct: 362 IAHITMYLVFLIAAILR----PTIGFYFAWTDSIEVTV-------QALEIFMYAYVMGLA 410 Query: 469 WSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPRE 528 + + +G + W D +++ +L + +RE A + R Sbjct: 411 LEKGILFYRVGRDGFFAFWWRWFDAAL--IFIFLFSLIFFTGKWGKRE-AFDPS-SVDRM 466 Query: 529 KWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILV 588 W +++ LL E + A + S LK Y + +G +S+ + V + ++ + + Sbjct: 467 HWPSFEFSLLHEICLAIACVLSILKCFYYAQMMKSIGGSVISVGKCVGKTYTYILIMVAI 526 Query: 589 IFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFG 648 I +FS GLN ++ Y + + +G T D+ + + + + LFW+ FG Sbjct: 527 IVSFSVGLNIIVDPY--LNRSTMKIGDQDYTKTT----DS---YETIGTSSKNLFWSIFG 577 Query: 649 LVDLDSF---------ELDGIK-IFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLI 698 + +F +D +K ++ Y + Sbjct: 578 YLGPSTFTTVVGNTGPNMDPVKHTLNSSTFEILAAVYHGILIITVLNLMTSILVKGADEV 637 Query: 699 SERADVEWKFARSKLWISYFEEGGTAPPPFNVL 731 + ++E+KF R+ ++ + APPP N++ Sbjct: 638 LDNEEMEFKFTRAAIYSEFLSWEMAAPPPLNLI 670 >UniRef50_A7SYK9 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 125 Score = 84.2 bits (199), Expect = 2e-14 Identities = 43/124 (34%), Positives = 69/124 (55%), Gaps = 6/124 (4%) Query: 639 MQTLFWAAFGLVDLDSFELDGIKI-FTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQL 697 + +LFW+ FGL +L+SF + K T+ G +MFG + S++ Sbjct: 1 LYSLFWSVFGLTELNSFGTNDAKFTITKETGEVMFGFFQVIAVIVAVNMLIAMMTRSFES 60 Query: 698 ISERADVEWKFARSKLWISYFEEG-GTAPPPFNVLPSP----KSLLYAWRWLQRRLCGHA 752 I+E ADV+WK +R++LW+S+ ++G G PPP N++P+P + L RW+ R C Sbjct: 61 IAEHADVKWKVSRTRLWMSWIQKGSGCLPPPLNLIPNPLLIFQGLKQFCRWVIRCGCRKV 120 Query: 753 RAKR 756 RA+R Sbjct: 121 RARR 124 >UniRef50_UPI0000E46FC7 Cluster: PREDICTED: similar to trpc3; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to trpc3 - Strongylocentrotus purpuratus Length = 595 Score = 75.4 bits (177), Expect = 8e-12 Identities = 58/213 (27%), Positives = 92/213 (43%), Gaps = 8/213 (3%) Query: 67 EKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXXXXXF 126 ++++ L +GDVA + +L + G +++D D G SAL +AI Sbjct: 13 QEQFFLAASKGDVAVIKALLDGRPENG-VDMDAKDESGLSALNLAITEGYLGVMYPLLEG 71 Query: 127 GVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLILAA 186 DA+L A+ +F EAV LL E + G E++ DITP+I AA Sbjct: 72 NAHIGDAMLRAVDADFHEAVRTLLQFAEERDESGRMAIINCRC-ESSDIHPDITPMIRAA 130 Query: 187 HRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXXXXX 246 +S+ I+K+LL+ +PE + D + D L+ S + Y Sbjct: 131 QLNSFAIVKMLLEADLLIPELN------TDAFQDEAADDLQRSVGTLEIYGGLASEAYVC 184 Query: 247 XXXKDPILTAFELSWELRRLSALEHEFKTEYQE 279 DPI AF L ++R++ LE +QE Sbjct: 185 LASTDPIDRAFTLCGIMKRIAILEINTVLTFQE 217 Score = 67.7 bits (158), Expect = 2e-09 Identities = 44/185 (23%), Positives = 92/185 (49%), Gaps = 13/185 (7%) Query: 328 LSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSL 387 + ++ AI+ Q++FVAHPN QQ +++ +Y + R + L+ + + FP +S+ Sbjct: 234 IPKVTQAIQYEQRQFVAHPNTQQAVSAQFYRHLAHLRDEPPLVNFLAFIGLVVAFPFFSI 293 Query: 388 AYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLS 447 Y + + +R P++KF+ + + F L +L+ I+T+ H+ ++ Sbjct: 294 LYKLGVSTHIRHLVRTPYVKFVMQAGADFSMLIILL----NIDTS------SHLHNIIMT 343 Query: 448 RRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRI 507 R IV +++L +V GL W E+ + G+R+ + ++ D + + L + L Sbjct: 344 RN---QYIVHFILLLFVVGLSWKEMYLAYLCGIRKIMSSFEHIRDTLISILLMVYFVLTF 400 Query: 508 VSHYQ 512 +S +Q Sbjct: 401 LSMFQ 405 Score = 50.0 bits (114), Expect = 3e-04 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Query: 529 KWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILV 588 KW+ DP L+ G+F + + KL+ N +GPL +S+ MV FF+ I V Sbjct: 498 KWN--DPSLIGNGIFGIVTVLAFTKLMSFLIANDFVGPLVISVGDMVKRTSSFFIFVIAV 555 Query: 589 IFAFSCGLNQLLWYYADMEKKRCTVGTA 616 I +FS + Y+ + +RC A Sbjct: 556 IISFSSAMTFNYNIYSQGDIERCETNDA 583 >UniRef50_Q9TXE9 Cluster: TRP PROTEIN=140 kDa integral RHABDOMERAL photoreceptor protein/retina expressed gene product; n=1; Calliphora vicina|Rep: TRP PROTEIN=140 kDa integral RHABDOMERAL photoreceptor protein/retina expressed gene product - Calliphora vicina (Blue blowfly) (Calliphora erythrocephala) Length = 115 Score = 74.9 bits (176), Expect = 1e-11 Identities = 31/43 (72%), Positives = 38/43 (88%) Query: 564 LGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADM 606 LGPLQVSL RM++DI+KFF + LV+FAF CGLNQLLWYYA++ Sbjct: 1 LGPLQVSLGRMIIDIIKFFFIYTLVLFAFGCGLNQLLWYYAEL 43 Score = 58.4 bits (135), Expect = 9e-07 Identities = 28/79 (35%), Positives = 48/79 (60%), Gaps = 4/79 (5%) Query: 706 WKFARSKLWISYFEEGGTAPPPFNVLPSPKSL--LYAWRWLQRRLCGHARAKREHMRTIR 763 W +A +LW+SYFE+GGT PPPFN+ PS K + ++ + +R +++ + Sbjct: 38 WYYA--ELWMSYFEDGGTVPPPFNMFPSVKLMRKVFGKQRPKRSRSFMLKSRVKAQSLHE 95 Query: 764 AIMRNLVRRYVTVQQRRAE 782 +M+ L+RRY+T +QR + Sbjct: 96 RVMKLLIRRYITAEQRHRD 114 >UniRef50_UPI0000E4A58D Cluster: PREDICTED: similar to transient receptor potential channel 4 beta splice variant; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to transient receptor potential channel 4 beta splice variant - Strongylocentrotus purpuratus Length = 243 Score = 74.1 bits (174), Expect = 2e-11 Identities = 60/222 (27%), Positives = 102/222 (45%), Gaps = 7/222 (3%) Query: 49 EEENVVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSAL 108 EE +++P ++ LS ++ + G+VA + +++ + G IN++ + G +AL Sbjct: 4 EEAELIQPSEDSEALSGQDA-FFQAAANGEVATLKALVENRLELG-INLNGRNDSGYTAL 61 Query: 109 LMAIDXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEAL 168 +A+ V DALL A EF AV+ LL++ E+ + E + Sbjct: 62 QIAVTEGYVVIITELLRLDVLVGDALLRAAETEFEHAVKCLLEYAEQ-KPEDERDRIINC 120 Query: 169 PPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRH 228 E + F +TP++ AA +++Y I+K LLD GA++PE G + DSL Sbjct: 121 RCEGSDFHPLLTPIMRAAQKNNYSIVKRLLDAGARIPET-KYASGSGG---ATTVDSLLQ 176 Query: 229 SRSRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALE 270 S + Y DPI AF+L+ L ++S E Sbjct: 177 SVGLVEQYSAIATPAYVTQAYNDPIDKAFQLTKTLNKISYAE 218 >UniRef50_Q7T1G6 Cluster: Ion channel NompC; n=4; Danio rerio|Rep: Ion channel NompC - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1614 Score = 71.3 bits (167), Expect = 1e-10 Identities = 121/480 (25%), Positives = 184/480 (38%), Gaps = 68/480 (14%) Query: 252 PILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQILLNHEKGA 311 P+ TA LS L + E E + Q C+ A+ LL + ++ GA Sbjct: 1094 PLDTAVRLSRALTLCALREKERSVDLQAAAHHCELMASDLLSLSASAG------GQGAGA 1147 Query: 312 SPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQ 371 P A + LS L I+ RQK V+ P VQ L +W + K +LL Sbjct: 1148 GPILR-----ALDHRGLSVLDCLIEGRQKGVVSQPAVQTYLTEVWCGGLQWDSWKILLLF 1202 Query: 372 AAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIET 431 ++ PL+ L + HS T+ P +KF+ H S+ L L IL I Sbjct: 1203 CCLLL----CPPLWLLLALPLTHSF--NTI--PIVKFMSHLVSHIFLLTLFILT---IVY 1251 Query: 432 APGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVI 491 P VS PLS+ MPS E L+L W+ G++ SE L G R + W Sbjct: 1252 PP------VS---PLSQARLMPSWSECLLLIWLCGMLVSE---LTFPGERTGL--AW--- 1294 Query: 492 DFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSS 551 L + A ++ H +A+ QW P + L + A Sbjct: 1295 ---IRLLLLGFSAAALLCHL-----LAVFTQWWPPTHL----HCLFARNVLLAVAMTLGF 1342 Query: 552 LKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRC 611 ++L+ + + GP + + ++ D+ +F V+ +L AF+ L L E+ Sbjct: 1343 IQLLEFLTFHHLFGPWAIIIRDLIKDLCRFAVILMLFHTAFTLSLTALCQPLYPQEQHNT 1402 Query: 612 TVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSF-ELDGIKIFTRFWGML 670 T T+P P LF+A FGL + D ++D T + Sbjct: 1403 TTEV------TVPGP---------LNMSVLLFFALFGLTEPDKIPDVDRSPPATAVLAKM 1447 Query: 671 MFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNV 730 +FG Y +YQ I ++D EWKF R+ L + G P PFN+ Sbjct: 1448 VFGVYLVVTFIVLINLLIAMMSDTYQRIQAQSDTEWKFGRAVLIRDMSRKSG-IPSPFNL 1506 >UniRef50_Q5C082 Cluster: SJCHGC03783 protein; n=1; Schistosoma japonicum|Rep: SJCHGC03783 protein - Schistosoma japonicum (Blood fluke) Length = 329 Score = 69.3 bits (162), Expect = 5e-10 Identities = 31/77 (40%), Positives = 48/77 (62%) Query: 530 WDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVI 589 W DP +S+ LF+ N+ S ++ Y+ LGPLQ+SL+RMV DI++F L +++ Sbjct: 231 WAPDDPEYISDCLFALGNVLSFSRISYLMPAWELLGPLQISLARMVSDIIRFMALFTVMV 290 Query: 590 FAFSCGLNQLLWYYADM 606 AF GL L WY+A++ Sbjct: 291 IAFVVGLTNLYWYFANI 307 Score = 68.5 bits (160), Expect = 9e-10 Identities = 41/128 (32%), Positives = 71/128 (55%), Gaps = 7/128 (5%) Query: 397 VGRTLRKPFIKFLCHSASYFMFLFLLILASQRIET---APGGLLWDVSHDEPLSRRGSMP 453 V LR P KFL H SY FL L+ +A+ R++ + W+V + E LS Sbjct: 45 VTEILRCPVTKFLGHMVSYLTFLMLITVATFRLDRTTISDDEDNWEVRYTEILSYDFRTS 104 Query: 454 SIV----EWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVS 509 ++V + ++L W+ G + E KQ++ GLR + +N +D+V+ +LY+A+ +LRI+ Sbjct: 105 NVVMTKIQIILLFWILGQLCMECKQVYHYGLRYFFRSYYNFMDWVSIALYLASYSLRIIV 164 Query: 510 HYQVRREM 517 ++V+ M Sbjct: 165 DFKVQASM 172 >UniRef50_Q5C0X3 Cluster: SJCHGC09110 protein; n=1; Schistosoma japonicum|Rep: SJCHGC09110 protein - Schistosoma japonicum (Blood fluke) Length = 188 Score = 62.1 bits (144), Expect = 8e-08 Identities = 52/190 (27%), Positives = 80/190 (42%), Gaps = 27/190 (14%) Query: 534 DPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFS 593 DP ++S+ +F+ AN+ S ++ + P + S +RM+ DI +F VL +LV+FAF Sbjct: 9 DPEIVSDVMFAVANVVSFARIKIMGE--PFY---KYSFTRMLTDITRFMVLYLLVLFAFM 63 Query: 594 CGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLD 653 GL+ L WYY K T T A ++ L T+ +LFW+ F V + Sbjct: 64 VGLHNLYWYYGLQTFKIYDEATNTTQTQV-----ATEMFEGLRHTLYSLFWSMFSQVSIS 118 Query: 654 SFEL-----------DGI------KIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQ 696 + DG+ GM++F Y HS++ Sbjct: 119 KLPIRKPDQAEHKYTDGMIDSDSPTTIVDSVGMVLFAVYHGIIIIVLVNMLIAMMSHSFE 178 Query: 697 LISERADVEW 706 I E DVEW Sbjct: 179 SIQEDCDVEW 188 >UniRef50_Q0Z852 Cluster: TRP-like ion channel; n=2; Chlamydomonas reinhardtii|Rep: TRP-like ion channel - Chlamydomonas reinhardtii Length = 901 Score = 60.5 bits (140), Expect = 2e-07 Identities = 65/274 (23%), Positives = 122/274 (44%), Gaps = 33/274 (12%) Query: 460 ILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAM 519 + W + ++ EV++ + G EY+ WNV+D T+AL + HY + R +A+ Sbjct: 540 LAVWCAAILVDEVQEYVEEGRAEYMSSGWNVMD--------VTMALSYILHY-ILRIIAV 590 Query: 520 GLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPL-QVSLSRMVLDI 578 + D + +L+ L +AA + + ++V +F ++ +GPL Q+ ++ D+ Sbjct: 591 RVT--------DNLNILLVVNDLLAAAALMAWFRMVSVFELSSAIGPLIQMMKQMLIKDV 642 Query: 579 LKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCT-VGTALTPNGTLPDPDACVVWRRLFE 637 +F +L ++++ FS G+ + L+ A +E+ T T T G D L Sbjct: 643 TRFALLVLVILLGFSVGM-EALFQEACIERDPTTNECTKYTSWGYDWQKDG------LVG 695 Query: 638 TMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQL 697 M L + A G + FE R G++ + + +Y Sbjct: 696 GMTFLQYIALGNANPVDFEQ------KRVTGVIFYLIFAIVTAILLLNLFIAMLADTYTR 749 Query: 698 ISERADVEWKFARSKLWISYFEEGGTAPPPFNVL 731 +S +A VE+++ ++KL SY PPFN+L Sbjct: 750 VSTQAMVEFRYRKAKLMASYSRRDFVC-PPFNLL 782 >UniRef50_A5A3A6 Cluster: TRPC1 splice variant; n=7; Euteleostomi|Rep: TRPC1 splice variant - Homo sapiens (Human) Length = 129 Score = 58.0 bits (134), Expect = 1e-06 Identities = 43/138 (31%), Positives = 69/138 (50%), Gaps = 11/138 (7%) Query: 476 WDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDP 535 W GL +++ + N + FV NSLY+AT AL++V+H + + A W W Sbjct: 1 WYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKF-HDFADRKDW-----LWYEGLE 54 Query: 536 MLLSEGLFSAANIFSSLKL-VYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSC 594 L E + + +SL L + V H ++S+ +M+ D KF + +LV+F+F+ Sbjct: 55 DFLEESRNQLSFVMNSLYLATFALKVVAH---NKISMGQMLQDFGKFLGMFLLVLFSFTI 111 Query: 595 GLNQLL-WYYADMEKKRC 611 GL QL Y E+K C Sbjct: 112 GLTQLYDKGYTSKEQKDC 129 Score = 43.2 bits (97), Expect = 0.037 Identities = 17/39 (43%), Positives = 28/39 (71%) Query: 475 LWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513 LW GL +++ + N + FV NSLY+AT AL++V+H ++ Sbjct: 48 LWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKI 86 >UniRef50_UPI0000F1ED97 Cluster: PREDICTED: similar to putative TRP cation channel; n=2; Danio rerio|Rep: PREDICTED: similar to putative TRP cation channel - Danio rerio Length = 1378 Score = 57.6 bits (133), Expect = 2e-06 Identities = 75/284 (26%), Positives = 123/284 (43%), Gaps = 57/284 (20%) Query: 322 APERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYE--SVPGFRRKNMLLQAA-EMVRI 378 +P R + L LA++ K F+AH VQ LL IW SV K +L ++ Sbjct: 663 SPSWGRSTCLWLALEAHDKSFIAHSGVQALLTQIWCGELSVDNPHWKVLLCMIFFPLIYT 722 Query: 379 GAM-FPLYSLAYIAAPHSAVGRT---LRKPFIKFLCHSASYFMFLFLLILASQRIETAPG 434 G + F L P + R L+ P +KF + ASYF FL+L + Sbjct: 723 GFLTFRSKLLKAFGNPLNCSSRLMSFLKSPQVKFYWNIASYFGFLWLFAVV--------- 773 Query: 435 GLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWD----MGLRE----YVHD 486 L+ D + PS E L+ W++ L+ E++QL+ G R Y+ D Sbjct: 774 -LMIDFQ---------TSPSWRELLLYVWLTSLVCEEIRQLYHDFDGSGFRRKAKMYIKD 823 Query: 487 MWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAA 546 +WN++D ++ L++A + R+ + V + + + Sbjct: 824 LWNILDVLSIVLFIAGLICRLQASDTV----------------------FYIGKVILCID 861 Query: 547 NIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKF-FVLDILVI 589 I L+L+ IFS++ LGP + + RM+LD+ F F+L I V+ Sbjct: 862 FIIFCLRLMAIFSISRTLGPKIIIVRRMMLDLFFFMFLLSIWVV 905 >UniRef50_A7RZ54 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 769 Score = 55.6 bits (128), Expect = 7e-06 Identities = 59/225 (26%), Positives = 99/225 (44%), Gaps = 37/225 (16%) Query: 451 SMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSH 510 S PS L + G I +EV+Q + Y DMWN +D Y+ V +RIV+ Sbjct: 392 SSPSRSSTSFLFFFLGRILAEVQQYQRSRSKIYFRDMWNYLDMAIILCYITIVIVRIVT- 450 Query: 511 YQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVS 570 MA + P + + ++ L+ +F L+L + +N GPLQ++ Sbjct: 451 ------MAK----SGPVQGNNLLAGVMY---LYGINTLFLILRLSSVLELNRTTGPLQLA 497 Query: 571 LSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPD--- 627 L RM++D+ V ++VI AFS + ++ Y+A + +T +G P Sbjct: 498 LMRMLVDLWVIIVQFVVVILAFSFAITKI--YFAQRDLALGHAQANVTYSGFCPFDGGTD 555 Query: 628 ----------ACV--------VWRRLFETMQTLFWAAFGLVDLDS 654 C+ +++ L +T ++L W+ FGL DLDS Sbjct: 556 FLELFLLYFLCCITIFLFDFLIYQSLEKTAESLVWSLFGLTDLDS 600 >UniRef50_Q4RQP9 Cluster: Chromosome 2 SCAF15004, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 2 SCAF15004, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1224 Score = 53.2 bits (122), Expect = 3e-05 Identities = 104/436 (23%), Positives = 174/436 (39%), Gaps = 83/436 (19%) Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPL-YSLAY 389 L+LA++ + FVA VQ LL IW + +L MV +FPL Y+ Sbjct: 638 LQLALEANDQDFVAQSGVQALLTKIWCGELSVDNPVWRVLLC--MV----VFPLIYTGFL 691 Query: 390 IAAPHSAVGRTLRK----------PFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWD 439 I GR RK P +KF + SYF FLFL + L+ D Sbjct: 692 IFRSGLTSGREFRKAMWLRCLYSCPQVKFYWNIVSYFAFLFLFAVV----------LMVD 741 Query: 440 VSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMG--------LREYVHDMWNVI 491 +PS E L+ W+ L++ EV+QL+D R Y+ D+WN++ Sbjct: 742 FQ---------LVPSKWELLLYVWLLTLVFEEVRQLFDYRPDLEIWKKARLYISDVWNIL 792 Query: 492 DFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSS 551 D ++ L++ ++LR + R + L + + W + + + Sbjct: 793 DSLSIVLFITGLSLRCHAVLPRVRLLTSILCF-----RLTTW-LFYPGKVILCITFVVFC 846 Query: 552 LKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRC 611 L+L+ IF+++ LGP + + RM+ D+ F L + + A+ +L D + + Sbjct: 847 LRLMAIFTISRTLGPKIIIVRRMMTDMFFFMFLLSIWVVAYGVAKQGIL---IDNDDR-- 901 Query: 612 TVGTALTPNGTLPDPDACVVWRRLFETMQT-LFWAAFGLVDLDSFELDG----------- 659 A G L +P +R +F T + +AAF D+D+ ++G Sbjct: 902 ---PAWILRGVLYEP-----YRIIFGDFPTNIDYAAF---DIDACSVNGTNRLKPKCPVL 950 Query: 660 ----IKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWI 715 + F + ++M Y ++Q + + D WKF R +L I Sbjct: 951 NEHQMPAFPEWLTIIMLCIYLLFANILLLNLLIAIFNFTFQEVQDNTDKIWKFQRYQL-I 1009 Query: 716 SYFEEGGTAPPPFNVL 731 + APPP VL Sbjct: 1010 KEYHSRPPAPPPLIVL 1025 >UniRef50_O94759 Cluster: Transient receptor potential cation channel subfamily M member 2; n=29; Tetrapoda|Rep: Transient receptor potential cation channel subfamily M member 2 - Homo sapiens (Human) Length = 1503 Score = 51.6 bits (118), Expect = 1e-04 Identities = 69/280 (24%), Positives = 117/280 (41%), Gaps = 61/280 (21%) Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVP---GFRRKNMLLQAAEMVRIGAM-FPLYS 386 L+LA++ + KFV+H +Q L +W+ + G R + + A ++ G + F Sbjct: 718 LQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKR 777 Query: 387 LAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPL 446 L + P + P + F + SYF FL L L+ D +P Sbjct: 778 LQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYV----------LMVDF---QP- 823 Query: 447 SRRGSMPSIVEWLILAWVSGLIWSEVKQLW----DMGLRE----YVHDMWNVIDFVTNSL 498 +PS E I W+ L+ E++QL+ + GL + Y D WN +D L Sbjct: 824 -----VPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILL 878 Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVY 556 +VA + R++ P L G + S I L+L++ Sbjct: 879 FVAGLTCRLI--------------------------PATLYPGRVILSLDFILFCLRLMH 912 Query: 557 IFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596 IF+++ LGP + + RM+ D+ FF L +L ++ S G+ Sbjct: 913 IFTISKTLGPKIIIVKRMMKDV--FFFLFLLAVWVVSFGV 950 >UniRef50_A7T1N0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1551 Score = 49.6 bits (113), Expect = 4e-04 Identities = 73/361 (20%), Positives = 134/361 (37%), Gaps = 68/361 (18%) Query: 404 PFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAW 463 PF KF+ + Y F+FL +L++ +P G + E ++ W Sbjct: 837 PFSKFVGNVVGYLAFIFLYAYV----------VLFNFPRFDPAKTLGGIHP-TEIVLYFW 885 Query: 464 VSGLIWSEVKQLWDMG-------LREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRRE 516 V ++ E++QL + Y D WN +D + ++++ + LR ++ ++ Sbjct: 886 VFTILIEEIRQLAAKPPKYIKDKVSVYFSDTWNFVDIFSLTVFIIAIILRFFTNSRI--- 942 Query: 517 MAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVL 576 S + S IF ++ + IFSVN LGP V + +M+ Sbjct: 943 -------------------FTASRIILSLDIIFFIVRSLQIFSVNRLLGPKLVMIQKMMQ 983 Query: 577 DILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLF 636 D+ +F ++ + A+ L+ +++ + + T W + Sbjct: 984 DLAQFIIILAVFTIAYGIALHAVMFPSPGIYARNNT-------------------WVTIT 1024 Query: 637 ETMQTLFWAAFGLVDLDSFELDGIKIF------TRFWGMLMFGTYXXXXXXXXXXXXXXX 690 +Q +W +G + LD + + K F R+ L+ Y Sbjct: 1025 SVVQYPYWQMYGELFLDEIQGEKPKEFGEVDPDGRWLSPLLLAIYMVFTNILLLNLLIAI 1084 Query: 691 XXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLCG 750 ++++ + E +D WKF R L Y APP VL + W W R CG Sbjct: 1085 FNYTFERVQEDSDKVWKFQRYDLVQEYHSRPVFAPP--LVLLGHILIFIRWVWRMCR-CG 1141 Query: 751 H 751 H Sbjct: 1142 H 1142 >UniRef50_A7SD04 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1108 Score = 49.6 bits (113), Expect = 4e-04 Identities = 54/279 (19%), Positives = 113/279 (40%), Gaps = 28/279 (10%) Query: 480 LREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLS 539 LR+Y+ D WN++D +T YV + LR+++ W R K + ++ Sbjct: 649 LRKYLSDRWNILDLLTLLSYVIILILRVIT-------------WAS-RAKVSQNRLLAVA 694 Query: 540 EGLFSAANIFSSLKLV-YIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQ 598 L+ + +L++ ++ G +Q++L +++ ++ F + AFS + + Sbjct: 695 GYLYGLNAMLLTLRVFGHMMESKKSTGAIQIALFQIIGAVVAIFGQFLAATVAFSLAITK 754 Query: 599 LLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELD 658 + M + ++ +G P W ++ L W+ GL D S LD Sbjct: 755 IY-----MVEVSYATPSSNASHGFCSKPGLNCWWG----AVRHLSWSLLGLADTSS--LD 803 Query: 659 GIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYF 718 F+ +++G + ++YQ + + + EW + ++ + I + Sbjct: 804 SSDGFSEGLAKVLYGLFLIMGVVMLMNMMIALLSNTYQQVEDNSFYEWSYKKA-ITIRTY 862 Query: 719 EEGGTAPPPFNVLPSPKSLL-YAWRWLQRRLCGHARAKR 756 P PFN++ L+ Y W+ ++R C KR Sbjct: 863 SGYHPVPVPFNIVSLFVLLVGYLWKSCRQRCCYAVYEKR 901 >UniRef50_Q7Z2W7 Cluster: Transient receptor potential cation channel subfamily M member 8; n=26; Tetrapoda|Rep: Transient receptor potential cation channel subfamily M member 8 - Homo sapiens (Human) Length = 1104 Score = 48.8 bits (111), Expect = 7e-04 Identities = 56/270 (20%), Positives = 113/270 (41%), Gaps = 37/270 (13%) Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYI 390 L+LA++ + F+A P VQ L+ WY + + ++ ++ PL ++ Sbjct: 657 LELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFII------PLVGCGFV 710 Query: 391 AAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRG 450 + V + + + ++ + +F + ++ + LL D Sbjct: 711 SFRKKPVDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFH--------- 761 Query: 451 SMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSH 510 S+P E ++ + V L EV+Q + G+ Y D+WNV+D + ++A + R+ H Sbjct: 762 SVPHPPELVLYSLVFVLFCDEVRQWYVNGVN-YFTDLWNVMDTLGLFYFIAGIVFRL--H 818 Query: 511 YQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVS 570 + + G +F I +L+L++IF+V+ +LGP + Sbjct: 819 SSNKSSLYSG-------------------RVIFCLDYIIFTLRLIHIFTVSRNLGPKIIM 859 Query: 571 LSRMVLDILKFFVLDILVIFAFSCGLNQLL 600 L RM++D+ F L + + AF +L Sbjct: 860 LQRMLIDVFFFLFLFAVWMVAFGVARQGIL 889 >UniRef50_UPI000065CCB2 Cluster: Transient receptor potential cation channel subfamily M member 4 (Long transient receptor potential channel 4) (hTRPM4) (Melastatin-4) (Calcium-activated non-selective cation channel 1).; n=1; Takifugu rubripes|Rep: Transient receptor potential cation channel subfamily M member 4 (Long transient receptor potential channel 4) (hTRPM4) (Melastatin-4) (Calcium-activated non-selective cation channel 1). - Takifugu rubripes Length = 615 Score = 48.4 bits (110), Expect = 0.001 Identities = 67/336 (19%), Positives = 125/336 (37%), Gaps = 62/336 (18%) Query: 404 PFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAW 463 P FL + YF+FL L LL D P S P++ E+++ W Sbjct: 202 PVTSFLGNVLMYFLFLLLFAYV----------LLVDFKPPPP-----SGPAVSEYVLYFW 246 Query: 464 VSGLIWSEVKQ-------LWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRRE 516 V ++ E+++ W R Y+ D+WN D + +L++ ++ R+ + Sbjct: 247 VFTIVCEEIRETLFVGMMTWRQRFRVYIQDVWNKCDLIAIALFIIGLSCRMFT------- 299 Query: 517 MAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVL 576 W+ + + +L+L++IF+++ LGP + + +M+ Sbjct: 300 ------WSYE-----------FGRNILCVDYMVFTLRLIHIFAIHKQLGPKIIIVGKMMK 342 Query: 577 DILKFFVLDILVIFAFSCGL-NQLLWYYADMEKKRCTVGTALTPN----GTLPDPDACVV 631 D+ FF L L ++ + G+ NQ L Y D R P G +P + V Sbjct: 343 DV--FFFLFFLGVWLMAYGVANQALLYSYDPRLDRIFRRVFYRPYLHIFGQIPVEEMDVG 400 Query: 632 WRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFW-GMLMFGTYXXXXXXXXXXXXXXX 690 E + + G + +++ W +++ Y Sbjct: 401 KAWDMECTENVTMIQNG--------SEPCRVYYSNWLVVILLVVYLLVTNILLINLLIAM 452 Query: 691 XXHSYQLISERADVEWKFARSKLWISYFEEGGTAPP 726 H++ + +D+ WKF R L + Y APP Sbjct: 453 FSHTFTEVQANSDIYWKFQRYNLIVQYHSRPSLAPP 488 >UniRef50_Q4A520 Cluster: Putative transient receptor potential channel; n=3; Deuterostomia|Rep: Putative transient receptor potential channel - Xenopus laevis (African clawed frog) Length = 1521 Score = 48.4 bits (110), Expect = 0.001 Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 20/142 (14%) Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYI 390 L I+ QK VAHP VQ+ L +WY ++ K +LL + A P++ + + Sbjct: 1082 LDCLIECEQKDVVAHPAVQKYLTEVWYGNLDWTTWKLVLLFFTFL----ACPPVWLVFSL 1137 Query: 391 AAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRG 450 H R + P +KF+ + AS+ +FL++L I P P+ Sbjct: 1138 PLKH----RFNKIPIMKFMSYLASH---IFLIVLFILTIVYPPLS---------PIYEGH 1181 Query: 451 SMPSIVEWLILAWVSGLIWSEV 472 +P EWL+LAW+SG++ SE+ Sbjct: 1182 MVPCWNEWLLLAWLSGMLVSEL 1203 Score = 44.8 bits (101), Expect = 0.012 Identities = 45/192 (23%), Positives = 74/192 (38%), Gaps = 13/192 (6%) Query: 542 LFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLW 601 L A S ++ + + + GP + + ++ D+ +F V+ L AF+ L+ + Sbjct: 1251 LLGMAMTLSFVQFLEFLTFHHLFGPWAIIIRDLIKDLTRFAVILALFHVAFTMQLSAVYQ 1310 Query: 602 --YYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSF-ELD 658 Y D + + + DP V LF++ FGLV+ L+ Sbjct: 1311 PVYPDDTATQSLNETETVHSESNIQDPIDITV---------LLFFSLFGLVEPGCLPSLN 1361 Query: 659 GIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYF 718 FT +FG Y +YQ I ++D EWKF R+ L Sbjct: 1362 RTPQFTFVIVRFVFGVYLIVTLIVLINLLIAMMSDTYQRIQAQSDTEWKFGRATLIRDMT 1421 Query: 719 EEGGTAPPPFNV 730 + GT P PFN+ Sbjct: 1422 RKPGT-PSPFNL 1432 >UniRef50_Q4SEW5 Cluster: Chromosome undetermined SCAF14611, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14611, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1342 Score = 47.6 bits (108), Expect = 0.002 Identities = 36/155 (23%), Positives = 74/155 (47%), Gaps = 30/155 (19%) Query: 453 PSIVEWLILAWVSGLIWSEVKQLW-------DMGLREYVHDMWNVIDFVTNSLYVATVAL 505 PS+ EW ++A++ L +V+Q+ + ++ D WN+ D V S+++ + L Sbjct: 898 PSLQEWTVIAYIITLGLEKVRQILMSEPGKLKQKINVWLEDYWNITDLVAISVFLLGLLL 957 Query: 506 RIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLG 565 R+ + E +MG ++ IF ++++ IF VN +LG Sbjct: 958 RL------QNEPSMGY-----------------GRVIYCVDIIFWYIRVLDIFGVNKYLG 994 Query: 566 PLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL 600 P + + +M++D+L F V+ ++V+ +F +L Sbjct: 995 PYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAIL 1029 >UniRef50_Q7Z4N2 Cluster: Melastatin 1; n=43; Euteleostomi|Rep: Melastatin 1 - Homo sapiens (Human) Length = 1533 Score = 47.6 bits (108), Expect = 0.002 Identities = 35/162 (21%), Positives = 75/162 (46%), Gaps = 30/162 (18%) Query: 446 LSRRGSMPSIVEWLILAWVSGLIWSEVKQLW-------DMGLREYVHDMWNVIDFVTNSL 498 L R PS+ EW++++++ L +++++ ++ ++ + WN+ D V S Sbjct: 780 LVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAIST 839 Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIF 558 ++ LR+ NQP M ++ IF ++++ IF Sbjct: 840 FMIGAILRLQ---------------NQPY--------MGYGRVIYCVDIIFWYIRVLDIF 876 Query: 559 SVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL 600 VN +LGP + + +M++D+L F V+ ++V+ +F +L Sbjct: 877 GVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAIL 918 >UniRef50_A7RLT7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1161 Score = 47.2 bits (107), Expect = 0.002 Identities = 41/147 (27%), Positives = 73/147 (49%), Gaps = 18/147 (12%) Query: 452 MPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHY 511 +PSI EW+++ +V L EV+Q+ V ++WN F +S + + V Sbjct: 795 VPSIEEWVLIGFVFSLCAEEVRQV-------RVINVWN-FSFFESSDWASNVWNLCDGFA 846 Query: 512 QVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSL 571 V +A+GL+ N + + ++S + ++L+ IFSV+ LGP V + Sbjct: 847 MVLFFLAVGLRLNP--------GTLRIGHLVYSLDIMLWIIRLLDIFSVSKDLGPYVVMI 898 Query: 572 SRMVLDILKFFVLDILVIFAFSCGLNQ 598 RM +D++ F V I+V+F + G+ Q Sbjct: 899 GRMTIDMMYFLV--IMVVFLLAYGVAQ 923 >UniRef50_UPI0000F1F31D Cluster: PREDICTED: hypothetical protein; n=2; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 415 Score = 46.4 bits (105), Expect = 0.004 Identities = 52/215 (24%), Positives = 90/215 (41%), Gaps = 49/215 (22%) Query: 404 PFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAW 463 P F+ + YF+FLFL LL D P P++ E+++ W Sbjct: 67 PVTSFIGNLLMYFLFLFLYAYV----------LLVDFKPPPP-----DGPAVSEYVLYFW 111 Query: 464 VSGLIWSEVKQLWDMGLRE-------YVHDMWNVIDFVTNSLYVATVALRIVSHYQVRRE 516 V L+ E+++ G ++ Y DMWN D + SL++ + R+ S Sbjct: 112 VFTLVCEEIREASIAGNKKFPQMLFVYAQDMWNKFDVLAISLFITGLCCRMFS------- 164 Query: 517 MAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVL 576 W+ + G+ + +L+L++IF+++ LGP + L +M+ Sbjct: 165 ------WS-----------FNMGRGILCVDYMVFTLRLIHIFAIHRQLGPKIIILGKMIK 207 Query: 577 DILKFFVLDILVIFAFSCGL-NQLLWYYADMEKKR 610 D FF L L+++ + G+ NQ L Y D R Sbjct: 208 D--AFFFLFFLLVWLSAYGVANQALLYQYDPSPAR 240 >UniRef50_UPI00003BFA30 Cluster: PREDICTED: similar to no mechanoreceptor potential C CG11020-PB, isoform B; n=1; Apis mellifera|Rep: PREDICTED: similar to no mechanoreceptor potential C CG11020-PB, isoform B - Apis mellifera Length = 268 Score = 46.4 bits (105), Expect = 0.004 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 2/102 (1%) Query: 639 MQTLFWAAFGLVDLDSFELDGIKI-FTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQL 697 ++ LF+A FG + F+++ + +T+ L FG Y +YQ Sbjct: 34 VELLFFAIFGQTTHEQFKVEITQPEWTKVLFKLTFGIYMLVSVVVLINLLIAMMSDTYQR 93 Query: 698 ISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLY 739 I ++D+EWK+ SKL + TAP P N+L + + L+ Sbjct: 94 IQAQSDIEWKYGLSKL-VRNMHRTNTAPSPLNLLTTWMTYLF 134 >UniRef50_Q7S8B0 Cluster: Predicted protein; n=1; Neurospora crassa|Rep: Predicted protein - Neurospora crassa Length = 1114 Score = 46.0 bits (104), Expect = 0.005 Identities = 67/287 (23%), Positives = 112/287 (39%), Gaps = 37/287 (12%) Query: 323 PERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIW------YESVPGFRRKNML---LQAA 373 P MR S L++AI+ K F++HP V Q L +IW Y + R+ + L +A Sbjct: 227 PAAMRTSTLEVAIRASAKHFLSHPLVVQQLEAIWNGAISFYSAADQLHRRTSIATDLSSA 286 Query: 374 EMVRIGAMFPLYSLAYIAAPHSAVGRTL---RKPFIKFLCHSASYFMFLFLLILASQR-I 429 + R + + G+ L R+ + AS F L + +R + Sbjct: 287 QSRRQSTVRTPLLGSQQGKEDRLRGQPLPLGRRSVTLYDPRQASVFKLSRLRVPRYRRFL 346 Query: 430 ETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWN 489 T G+L + L+ R S + +E + W +G + EV + G Y+ WN Sbjct: 347 STCSLGVLLCL-FMAVLNERSSTITTLELIFWFWSAGFMLDEVIGFNEHGFSLYIMSFWN 405 Query: 490 VIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIF 549 + D L + +RI + + DP L++ + Sbjct: 406 IFDLGILLLLIIYYCMRIYGVFLL--------------------DPHKLNDNAYDVLAAI 445 Query: 550 SSLKLVYIFSVNPH---LGPLQVSLSRMVLDILKFFVLDILVIFAFS 593 + L L IFS+ H L ++ M +D++ FVL I+V FS Sbjct: 446 AILLLPRIFSILDHYQYFSQLLIAFRLMAVDLVAVFVLVIVVCCGFS 492 >UniRef50_Q9P0L9 Cluster: Polycystic kidney disease 2-like 1 protein; n=31; Bilateria|Rep: Polycystic kidney disease 2-like 1 protein - Homo sapiens (Human) Length = 805 Score = 46.0 bits (104), Expect = 0.005 Identities = 47/201 (23%), Positives = 85/201 (42%), Gaps = 10/201 (4%) Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLL--WDVSHDEPLSRRGSMPSIV 456 R R FI F ++A+ +F L ++ A GG + W + + + + + Sbjct: 296 RGTRVVFIDFSVYNANINLFCVLRLVVEF---PATGGAIPSWQIRTVKLIRYVSNWDFFI 352 Query: 457 ---EWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513 E + ++ + E+ +L LR Y+ +WN++D V L + V I +V Sbjct: 353 VGCEVIFCVFIFYYVVEEILELHIHRLR-YLSSIWNILDLVVILLSIVAVGFHIFRTLEV 411 Query: 514 RREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSS-LKLVYIFSVNPHLGPLQVSLS 572 R M LQ ++ +A N+F + +K+ S N + L +L+ Sbjct: 412 NRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLA 471 Query: 573 RMVLDILKFFVLDILVIFAFS 593 R DIL F V+ +V FA++ Sbjct: 472 RCAKDILGFAVMFFIVFFAYA 492 >UniRef50_Q7S9R4 Cluster: Predicted protein; n=5; Pezizomycotina|Rep: Predicted protein - Neurospora crassa Length = 703 Score = 43.6 bits (98), Expect = 0.028 Identities = 35/137 (25%), Positives = 58/137 (42%), Gaps = 18/137 (13%) Query: 456 VEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR 515 +E + W++ + E+ + D G Y D+WN+ D ++ + LRI+ Sbjct: 308 LEIFLYLWLAAFSYDELSEWIDAGSIFYAADIWNIFDMAIMAIGFTFMVLRII------- 360 Query: 516 EMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMV 575 GL+ Q E D +L E L + S I S++P+ G L L M Sbjct: 361 ----GLE-TQNAELIDLAFDVLALEALLMVPRVCS------ILSLSPYWGTLIPCLKEMA 409 Query: 576 LDILKFFVLDILVIFAF 592 D +KF VL +++ F Sbjct: 410 KDFIKFMVLVVIIYLGF 426 >UniRef50_Q0UIA7 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 1133 Score = 43.2 bits (97), Expect = 0.037 Identities = 63/284 (22%), Positives = 114/284 (40%), Gaps = 29/284 (10%) Query: 322 APERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIW------YESVPGFRRK-----NMLL 370 AP R+S L++AI+ + KK +AHP V + L +IW + + RK Sbjct: 210 APRSARISALEIAIRAQAKKLLAHPLVVRQLEAIWAGTIVFHSAADNLHRKPDSSHRRSP 269 Query: 371 QAAEMVRIGAMFPLYSLAYIAAPHSA-VGRTLRKPFIKFLCHSASYFMFLFLLILASQRI 429 ++E + G + H A LR+ + H AS F L + + + Sbjct: 270 HSSEDISPGRGPSRRTPPSKQDDHQAPTAALLRRTVTLYDPHEASLFKLSRLRVPRYRNL 329 Query: 430 -ETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMW 488 T G++ + L+ + + +E L W +G + E+ + G Y+ +W Sbjct: 330 FSTLSFGIMLGL-FLAVLTEKSDDITALEVLFWFWSAGYMLDEIVGFSEQGFGLYIMSVW 388 Query: 489 NVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANI 548 N D + L +++Y +R + +QPR A+D +L S + + Sbjct: 389 NAFDL--------GILLMFMAYYILRLYGILMPDVDQPRVAAMAYD-VLGSTAVLLFPRL 439 Query: 549 FSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592 FS+L FS L ++ M +D++ VL ++ F Sbjct: 440 FSALDHYRYFS------QLLIAFKMMAMDLVAILVLIVISCSGF 477 >UniRef50_Q3ALE0 Cluster: Ankyrin; n=1; Synechococcus sp. CC9605|Rep: Ankyrin - Synechococcus sp. (strain CC9605) Length = 483 Score = 42.7 bits (96), Expect = 0.049 Identities = 27/74 (36%), Positives = 38/74 (51%) Query: 131 RDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLILAAHRDS 190 RD L I E V A D E + ++ E + P TF+ TPLI+AA + Sbjct: 305 RDQCLSLIEEHKVMAATEKGDAELVKQLIASGHTVETVYPHVNTFSDGHTPLIVAARDNH 364 Query: 191 YEIIKLLLDRGAQL 204 +I+KLLLD GA++ Sbjct: 365 LDIVKLLLDAGAEV 378 >UniRef50_A1CU15 Cluster: Cation channel family transporter, putative; n=6; Eurotiomycetidae|Rep: Cation channel family transporter, putative - Aspergillus clavatus Length = 1107 Score = 42.7 bits (96), Expect = 0.049 Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 5/169 (2%) Query: 327 RLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYS 386 R+S L++AI+ + K+F+AHP V Q L +IW ++ + L ++ R A Y Sbjct: 238 RISCLEVAIRTQAKRFLAHPVVVQQLEAIWAGTIVFHSAADSLHRSPVAARRDARL-TYG 296 Query: 387 LAYIAAPHSAV--GRTLRKPFIKFLCHSASYFMFLFLLI-LASQRIETAPGGLLWDVSHD 443 A A P + G R+ + AS F L + Q + T +L + Sbjct: 297 SASHAFPEAVPLNGSPPRRSVTLYDPRDASLFKLSRLRVPRYRQFLSTLSFAVLLGLFLA 356 Query: 444 EPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVID 492 RR + S +E + W +G + E+ + G Y+ WN+ D Sbjct: 357 VLQQRRVEI-STLEVIFWFWSAGFMLDEIVGFNEQGFSLYLMSFWNLFD 404 >UniRef50_Q8NLI7 Cluster: Uncharacterized membrane proteins; n=3; Corynebacterium|Rep: Uncharacterized membrane proteins - Corynebacterium glutamicum (Brevibacterium flavum) Length = 240 Score = 41.1 bits (92), Expect = 0.15 Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 9/119 (7%) Query: 761 TIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVEILRNSGMNTSTAN 820 TI + + YV+V +R + + E+ +D +A EL EIL + G++ TAN Sbjct: 65 TIAGAVSMALGEYVSVSSQRDTERVLIAKEAKELAEDPTAEHVELSEILHSYGISPETAN 124 Query: 821 AGAPEVMMLRAGGGG-----GKKNRQKERRLMKGFNIAPG---GSLAP-VDEFMSPVSW 870 A E+ A G G N Q L F+ A G+L P V F++P W Sbjct: 125 QAATEIGQGDALGAHLQLELGIDNEQLTSPLAAAFSSAVAFLLGALLPMVSVFIAPAGW 183 >UniRef50_A7SVF4 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 989 Score = 40.7 bits (91), Expect = 0.20 Identities = 31/130 (23%), Positives = 61/130 (46%), Gaps = 13/130 (10%) Query: 467 LIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVR------REMAMG 520 L + +K+++ M + EY WN++ V L ++ V L I+ + RE Sbjct: 789 LAYKNIKKIYRMKM-EYFKQTWNIVQLVVICLTLSAVVLFILRMLDTQKTIKKLRENPFV 847 Query: 521 LQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILK 580 Q +W + ++ +F S+L+L+Y+ S N H+ L S+SR +L Sbjct: 848 FVSFQYATQWAELNTYIVGIVIF-----LSTLRLLYLISFNRHISMLYNSISRS-FSLLA 901 Query: 581 FFVLDILVIF 590 F ++++++F Sbjct: 902 QFAVEVIIVF 911 >UniRef50_Q2UHE0 Cluster: Predicted protein; n=1; Aspergillus oryzae|Rep: Predicted protein - Aspergillus oryzae Length = 1049 Score = 40.7 bits (91), Expect = 0.20 Identities = 50/210 (23%), Positives = 83/210 (39%), Gaps = 13/210 (6%) Query: 310 GASPQAPLTEPGA-----PERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFR 364 G S Q P P A P R+S L++AI+ + K+F++HP V Q L +IW ++ Sbjct: 207 GGSQQPPGWTPTAGNKRLPGVARISCLEVAIRAQAKRFLSHPLVVQQLEAIWAGTIVFHS 266 Query: 365 RKNMLLQAAEMVRIGAMFPLYSLAYIA-APHSAVGR------TLRKPFIKFLCHSASYFM 417 + L ++ V A P Y A P+ G+ LR+ + AS F Sbjct: 267 AADYLHRSPTRVSHSA-GPTYGTTVTATTPNPFAGKLSPRSAELRRSVTLYDPRDASLFK 325 Query: 418 FLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWD 477 L + ++ + + L +R S +E + W +G + E+ + Sbjct: 326 LSRLRVPRYRQFLSTLSFAVLLALFLAVLDQRRVHISALEVVFWFWSAGFMLDELVGFNE 385 Query: 478 MGLREYVHDMWNVIDFVTNSLYVATVALRI 507 G Y+ WN+ D L LR+ Sbjct: 386 QGFSLYLMSFWNLFDLGILFLLFCYYCLRL 415 >UniRef50_A6R3T2 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 534 Score = 40.7 bits (91), Expect = 0.20 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 4/77 (5%) Query: 127 GVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSD---ITPLI 183 G + + AL+ A V+ VE LL + G N W A P+ A ++PL+ Sbjct: 76 GTDDKTALIIAYERGHVKVVELLLA-QNNVDLNGVVNDWSAPDPKIAVSRLSWRTMSPLL 134 Query: 184 LAAHRDSYEIIKLLLDR 200 AAH++ +++KLLLD+ Sbjct: 135 FAAHKNHADVLKLLLDQ 151 >UniRef50_UPI0000D569A5 Cluster: PREDICTED: similar to CG30078-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG30078-PA, isoform A - Tribolium castaneum Length = 1593 Score = 38.7 bits (86), Expect = 0.80 Identities = 18/55 (32%), Positives = 34/55 (61%) Query: 547 NIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLW 601 +I+ L ++ I SVN +LGPL + +MV +++ F VL ++V+ +F +L+ Sbjct: 872 SIYWYLHILNILSVNKYLGPLVTMMGKMVKNMIYFVVLLLIVLMSFGVSRQAILF 926 >UniRef50_UPI0000D55731 Cluster: PREDICTED: similar to polycystic kidney disease 2; n=1; Tribolium castaneum|Rep: PREDICTED: similar to polycystic kidney disease 2 - Tribolium castaneum Length = 705 Score = 38.7 bits (86), Expect = 0.80 Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 4/141 (2%) Query: 455 IVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVR 514 + E + A + E++++ LR Y W ID + + A + IV V Sbjct: 338 VFECTVYAIAGFFLAEEIREIIYFKLR-YFLQFWTYIDVIFLQMAFANLITSIVVFPNVD 396 Query: 515 REMAMGLQWN-QPREKWDAWDPMLLSEGLFSAANIFSS-LKLVYIFSVNPHLGPLQVSLS 572 + + +Q N Q + M + F+A+ +F S +KL + N +G L +L Sbjct: 397 -DAILKIQKNPQKYGNLEYLAEMRIFYNNFAASLLFFSYIKLFKYLNFNKTMGQLNNTLK 455 Query: 573 RMVLDILKFFVLDILVIFAFS 593 R DIL F ++ ++ FAF+ Sbjct: 456 RCAFDILGFSIMFFIIFFAFA 476 >UniRef50_UPI0000E4996E Cluster: PREDICTED: similar to transient receptor potential cation channel, subfamily M, member 3; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to transient receptor potential cation channel, subfamily M, member 3 - Strongylocentrotus purpuratus Length = 1282 Score = 38.3 bits (85), Expect = 1.1 Identities = 17/45 (37%), Positives = 32/45 (71%), Gaps = 2/45 (4%) Query: 552 LKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596 ++L++IFSVN HLGP + + +M+ D++ F + IL++F + G+ Sbjct: 918 IRLLHIFSVNKHLGPKLIMIIKMMNDLVVF--MCILMVFLLAYGI 960 >UniRef50_A6RWT7 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 791 Score = 38.3 bits (85), Expect = 1.1 Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 12/125 (9%) Query: 81 GTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXXXXXFGVETRDA-LLHAIS 139 G ++++ D G D + G++ L +AI E + L+ A+ Sbjct: 285 GNAKIVELLLDAGAKTED-IHFNGQTPLWLAIQMENAKIVALLLDKCAEIEEGHLMLAVE 343 Query: 140 EEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLILAAHRDSYEIIKLLLD 199 +E V+ V+ L+ ++R E+LP PL+ A ++Y+IIKLLLD Sbjct: 344 KEIVDIVDLLVQRVTKSRAKNMAGYGESLP----------RPLLSAIDNENYDIIKLLLD 393 Query: 200 RGAQL 204 GA++ Sbjct: 394 HGAEI 398 >UniRef50_Q0E967 Cluster: CG34123-PD, isoform D; n=12; Coelomata|Rep: CG34123-PD, isoform D - Drosophila melanogaster (Fruit fly) Length = 1921 Score = 37.9 bits (84), Expect = 1.4 Identities = 17/60 (28%), Positives = 35/60 (58%) Query: 542 LFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLW 601 ++ +I+ L+++ I VN +LGPL + +MV +++ F VL +V+ +F +L+ Sbjct: 924 IYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILY 983 >UniRef50_A0BSQ9 Cluster: Chromosome undetermined scaffold_125, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_125, whole genome shotgun sequence - Paramecium tetraurelia Length = 317 Score = 37.9 bits (84), Expect = 1.4 Identities = 17/38 (44%), Positives = 27/38 (71%) Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPH 208 + A+ S TPL +AA +YEI+K+LLD GA++ +P+ Sbjct: 131 DLASMDSGQTPLSIAAMTGNYEILKILLDAGAEVNKPN 168 >UniRef50_Q4SM12 Cluster: Chromosome 13 SCAF14555, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13 SCAF14555, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1504 Score = 37.5 bits (83), Expect = 1.8 Identities = 45/224 (20%), Positives = 95/224 (42%), Gaps = 40/224 (17%) Query: 453 PSIVEWLILAWVSGLIWSEVKQLW-------DMGLREYVHDMWNVIDFVTNSLYVATVAL 505 PSI EW++++++ L +V+Q+ + ++ + WN+ D ++ + L Sbjct: 1050 PSIQEWIVISYILTLGTEKVRQILMSEPGKLKQKISVWLEEYWNITDLAAICTFLLGLML 1109 Query: 506 RIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLG 565 R+ ++E MG ++ IF ++++ IF VN +LG Sbjct: 1110 RL------QQEPYMGY-----------------GRVIYCIDIIFWYIRVLDIFGVNKYLG 1146 Query: 566 PLQVSLSRMVL-DILKFF-----VLDILVIFAFSCG-LNQLLWYYADMEKKRCTVGTALT 618 P + + +MV+ +++ F ++ ++V SC + ++++ M + G A Sbjct: 1147 PYVMMIGKMVICELVGTFLVGANMIPVIVFVRVSCAQMIDMMYFVVIMLVVLMSFGVA-- 1204 Query: 619 PNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKI 662 + PD WR +W +G V DS +L ++I Sbjct: 1205 -RQAILHPDEEPTWRLARNIFYMPYWMIYGEVFADSIDLYAMEI 1247 >UniRef50_Q4RVK8 Cluster: Chromosome 15 SCAF14992, whole genome shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 15 SCAF14992, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1297 Score = 37.5 bits (83), Expect = 1.8 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 23/122 (18%) Query: 404 PFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAW 463 P FL + YF+FL L LL D P S P+I E+++ W Sbjct: 860 PVTSFLGNVLMYFLFLLLFAYV----------LLVDFKPPPP-----SGPAISEYVLYFW 904 Query: 464 VSGLIWSEVKQ-------LWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVS-HYQVRR 515 V ++ E+++ W R Y+ D+WN D +L++ + R+ S Y+ R Sbjct: 905 VFTIVCEEIRETLFVGTMTWRQRFRIYIQDVWNKCDITAITLFIIGLTCRMFSWSYEFGR 964 Query: 516 EM 517 ++ Sbjct: 965 DI 966 >UniRef50_Q2H0G7 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 1417 Score = 37.5 bits (83), Expect = 1.8 Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 2/45 (4%) Query: 314 QAPLTEPGAPE--RMRLSRLKLAIKLRQKKFVAHPNVQQLLASIW 356 Q PL G P+ +R S +++AI+ K+F++HP V Q L +IW Sbjct: 395 QTPLAPGGRPKPATLRTSAIEVAIRASAKQFLSHPLVTQQLEAIW 439 Score = 35.1 bits (77), Expect = 9.9 Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 11/148 (7%) Query: 446 LSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVAL 505 LS+R S + +E L W +G + E+ + G Y WN+ D L + + Sbjct: 541 LSQRSSKITSLELLFWFWSAGFMLDELVGFNEEGFSFYAMSFWNIFDLGILLLLIVYYCM 600 Query: 506 RIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLG 565 RI + + QWNQ A + +LL +F + + + + I L Sbjct: 601 RIYGVFLLDPH-----QWNQNAYDVLAVNAILLLPRIFGVLDHYRNFSRLLI-----SLR 650 Query: 566 PLQVSLSRMVLDILKFFVLDILVIFAFS 593 L V L+ + + +L F V FAFS Sbjct: 651 LLAVDLAAVFMLVLIGF-SGFFVFFAFS 677 >UniRef50_Q2GZU3 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 860 Score = 37.5 bits (83), Expect = 1.8 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 3/86 (3%) Query: 144 EAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQ 203 EA+E D + P +E PP+ + S TPL LAA EI++ LLD GA Sbjct: 118 EAIETDNDVDGNADADPAPELFEE-PPDPSIQPS-CTPLHLAAKNGHREIVEWLLDNGAD 175 Query: 204 LPEPHDVRCGCDDCVRSRREDSLRHS 229 + P C C ++S R S R S Sbjct: 176 IDAPSYRVCDCQS-LKSGRHPSRRLS 200 >UniRef50_A2QRW5 Cluster: Remark: TRP2; n=1; Aspergillus niger|Rep: Remark: TRP2 - Aspergillus niger Length = 1095 Score = 37.5 bits (83), Expect = 1.8 Identities = 44/183 (24%), Positives = 77/183 (42%), Gaps = 12/183 (6%) Query: 320 PGA--PERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVR 377 PG+ P R+S L++AI+ + K+F++HP V Q L +IW ++ + L ++ VR Sbjct: 225 PGSKRPAIARVSCLEVAIRAQAKRFLSHPLVVQQLEAIWAGTIVFHSASDYLHRSPAQVR 284 Query: 378 IGAMFPLYSLAYIAAPHSAVGRT-------LRKPFIKFLCHSASYFMFLFLLI-LASQRI 429 Y A +P R LR+ + AS F L + Q + Sbjct: 285 NNGRLQ-YGTAPDPSPLDTSHRQPQPNVSGLRRSVTIYDPRDASLFKLSRLRVPRYRQFL 343 Query: 430 ETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWN 489 T +L + L++R + +E + W +G + E+ + G Y+ WN Sbjct: 344 STLSFAVLLGL-FLAVLNQRRLEITPLEVIFWLWSAGFMLDEIVGFNEQGFSLYLMSFWN 402 Query: 490 VID 492 + D Sbjct: 403 LFD 405 >UniRef50_UPI0000DB7C9A Cluster: PREDICTED: similar to trp CG5996-PA, isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar to trp CG5996-PA, isoform A - Apis mellifera Length = 221 Score = 37.1 bits (82), Expect = 2.4 Identities = 17/71 (23%), Positives = 31/71 (43%), Gaps = 1/71 (1%) Query: 663 FTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGG 722 FT G + F + ++ ++E VEW F R++ ++ + Sbjct: 63 FTELIGYISFAGFTFISVIMILNMLIACMSNTMTKVTENVLVEWTFGRTETYVDFMLTT- 121 Query: 723 TAPPPFNVLPS 733 T PPPFN++P+ Sbjct: 122 TLPPPFNIIPT 132 >UniRef50_A4S1E9 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 338 Score = 36.7 bits (81), Expect = 3.2 Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%) Query: 166 EALPPETATFTSDIT-PLILAAHRDSYEIIKLLLDRGAQL 204 EA+ P T ++T PL AAH+ S+E++K+L+D GA + Sbjct: 222 EAVDPNARRSTGNLTTPLHEAAHKSSFEMVKVLIDAGADV 261 >UniRef50_Q9U1S7 Cluster: Putative uncharacterized protein pkd-2; n=2; Caenorhabditis|Rep: Putative uncharacterized protein pkd-2 - Caenorhabditis elegans Length = 716 Score = 36.7 bits (81), Expect = 3.2 Identities = 49/206 (23%), Positives = 90/206 (43%), Gaps = 16/206 (7%) Query: 397 VGRTLRKPFIKFLCHSASYFMFLFLLIL----ASQRIETAPGGLLWDVSHDEPLSRRGSM 452 + R R + F ++A+ +F + +L AS + T P + +D+ + + G+ Sbjct: 265 IDRGSRAIIVDFALYNANINLFCVVKLLFELPASGGVITTPKLMTYDLLTYQ--TSGGTR 322 Query: 453 PSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRI----V 508 I E + ++ I+ E+ + L Y+ WN++D V VAT+ L + Sbjct: 323 MMIFEGIFCGFILYFIFEELFAIGRHRLH-YLTQFWNLVDVVLLGFSVATIILSVNRTKT 381 Query: 509 SHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIF-SVNPHLGPL 567 +V + GL N P + + + L+ A +F + V+ F SVN + L Sbjct: 382 GVNRVNSVIENGLT-NAPFDDVTSSENSYLN---IKACVVFVAWVKVFKFISVNKTMSQL 437 Query: 568 QVSLSRMVLDILKFFVLDILVIFAFS 593 +L+R DI F V+ + FAF+ Sbjct: 438 SSTLTRSAKDIGGFAVMFAVFFFAFA 463 >UniRef50_Q9NZQ8 Cluster: MTR1; n=31; Euteleostomi|Rep: MTR1 - Homo sapiens (Human) Length = 1165 Score = 36.7 bits (81), Expect = 3.2 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 8/87 (9%) Query: 693 HSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGHA 752 +++Q++ AD+ WKF R L + Y E APP +L S SL L+R A Sbjct: 980 YTFQVVQGNADMFWKFQRYNLIVEYHERPALAPP--FILLSHLSLT-----LRRVFKKEA 1032 Query: 753 RAKREHM-RTIRAIMRNLVRRYVTVQQ 778 KREH+ R + + V + TVQ+ Sbjct: 1033 EHKREHLERDLPDPLDQKVVTWETVQK 1059 >UniRef50_A4RKC7 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 1142 Score = 36.7 bits (81), Expect = 3.2 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Query: 314 QAPLTEPGAPERM--RLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQ 371 Q P PG P+ R S L++AI+ K +AHP V Q L +IW ++ + + L + Sbjct: 176 QTPAGNPGRPKMAAARTSTLEVAIRASAKHLLAHPLVVQQLEAIWNGAIVFYSAADSLHR 235 Query: 372 AA 373 A+ Sbjct: 236 AS 237 >UniRef50_UPI00015B5D3F Cluster: PREDICTED: similar to CG34123-PD; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CG34123-PD - Nasonia vitripennis Length = 1679 Score = 36.3 bits (80), Expect = 4.3 Identities = 16/49 (32%), Positives = 30/49 (61%) Query: 552 LKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL 600 L+++ I VN +LGPL + +MV +++ F VL ++V+ +F +L Sbjct: 973 LRMLNILGVNKYLGPLVTMMGKMVKNMIYFVVLLLVVLMSFGVARQAIL 1021 >UniRef50_UPI00001C1FBC Cluster: PREDICTED: hypothetical protein; n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein - Homo sapiens Length = 228 Score = 36.3 bits (80), Expect = 4.3 Identities = 37/141 (26%), Positives = 51/141 (36%), Gaps = 7/141 (4%) Query: 808 ILRNSGMNTSTANAGAPEVMMLRAGGGGGKKNRQKERRLMKGFNIAPGGSLAPVDEFMSP 867 + R SG A +P GGG K + ER + GS + Sbjct: 5 LARGSGRPRLPAPGPSPPPSAPAQEGGGQKPQARTERGQRRALGQVQAGSPQREGDGRGS 64 Query: 868 VSWLQHDHGVPHYSLSTLLGPRLRASQSSLSDGPGAGMSASRRKPQHK--RRWGTIIDAA 925 + QH HG + + P Q + GPG G + +P + RRWG + A Sbjct: 65 RT-SQHGHGTERQNAARPRAPSAAGGQEQGAQGPG-GFRVRQTRPGGRGGRRWGRLERAH 122 Query: 926 RAARVSRL---IGRSRSEDSV 943 A V+ L GR RS V Sbjct: 123 AANAVAALGGWCGRPRSPSGV 143 >UniRef50_A6S4E5 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 953 Score = 36.3 bits (80), Expect = 4.3 Identities = 16/34 (47%), Positives = 23/34 (67%) Query: 323 PERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIW 356 P R+S L++AI+ K+F+AHP V Q L +IW Sbjct: 218 PVAARISTLEVAIRASAKRFLAHPLVVQQLEAIW 251 >UniRef50_Q96QT4 Cluster: Transient receptor potential cation channel subfamily M member 7; n=38; Deuterostomia|Rep: Transient receptor potential cation channel subfamily M member 7 - Homo sapiens (Human) Length = 1865 Score = 36.3 bits (80), Expect = 4.3 Identities = 33/154 (21%), Positives = 73/154 (47%), Gaps = 15/154 (9%) Query: 452 MPSIVEWLILAWVSGLIWSEVKQLW--DMGLREYVHDMWNVIDFVTNSLYVATVALRIVS 509 +PS+ EW+++A++ +V++++ + G +W D+ S +A I+S Sbjct: 881 LPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVW-FSDYFNISDTIA-----IIS 934 Query: 510 HYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVYIFSVNPHLGPL 567 + + + G +WN +A+D + G ++ IF ++L+ +VN GP Sbjct: 935 FF-IGFGLRFGAKWNFA----NAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPY 989 Query: 568 QVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLW 601 + + +MV ++ V+ LV+ +F +L+ Sbjct: 990 VMMIGKMVANMFYIVVIMALVLLSFGVPRKAILY 1023 >UniRef50_Q9NZM6 Cluster: Polycystic kidney disease 2-like 2 protein; n=26; Amniota|Rep: Polycystic kidney disease 2-like 2 protein - Homo sapiens (Human) Length = 624 Score = 36.3 bits (80), Expect = 4.3 Identities = 29/127 (22%), Positives = 62/127 (48%), Gaps = 8/127 (6%) Query: 471 EVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKW 530 EVK++ + Y +WN ++ + L + VA+ ++Y V+ + +G Q + EK+ Sbjct: 300 EVKKIKEFK-SAYFKSIWNWLELLL--LLLCFVAVSFNTYYNVQIFLLLG-QLLKSTEKY 355 Query: 531 DAWDPM----LLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDI 586 + + + + + F+ +K+ S N + L +LSR V DI+ F ++ Sbjct: 356 SDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFF 415 Query: 587 LVIFAFS 593 ++ FA++ Sbjct: 416 IIFFAYA 422 >UniRef50_Q574D7 Cluster: Ankyrin G217; n=8; Euteleostomi|Rep: Ankyrin G217 - Rattus norvegicus (Rat) Length = 1984 Score = 35.9 bits (79), Expect = 5.6 Identities = 16/31 (51%), Positives = 24/31 (77%) Query: 174 TFTSDITPLILAAHRDSYEIIKLLLDRGAQL 204 T +DITPL +A+ R + ++KLLLDRGA++ Sbjct: 247 TARNDITPLHVASKRGNANMVKLLLDRGAKI 277 >UniRef50_Q12955 Cluster: Ankyrin-3; n=78; root|Rep: Ankyrin-3 - Homo sapiens (Human) Length = 4377 Score = 35.9 bits (79), Expect = 5.6 Identities = 16/31 (51%), Positives = 24/31 (77%) Query: 174 TFTSDITPLILAAHRDSYEIIKLLLDRGAQL 204 T +DITPL +A+ R + ++KLLLDRGA++ Sbjct: 264 TARNDITPLHVASKRGNANMVKLLLDRGAKI 294 >UniRef50_Q8DA59 Cluster: Multidrug resistance protein D; n=39; Gammaproteobacteria|Rep: Multidrug resistance protein D - Vibrio vulnificus Length = 415 Score = 35.5 bits (78), Expect = 7.5 Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 4/100 (4%) Query: 372 AAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIET 431 A E ++ A FPL L + A +AVG+ + ++ + H AS F+ + A Sbjct: 9 AGEFAQMSASFPLAKLTLLIAILTAVGQMTQTMYVPSIGHMASEFLVSPAALQAVMACYL 68 Query: 432 APGGLLWDVSHDEPLS-RRGSMPSIVEWLILAWVSGLIWS 470 P GL V PLS R G P I+ L++ +++G + S Sbjct: 69 IPYGLSQFVY--GPLSDRLGRKPIIIAGLLI-YIAGTMLS 105 >UniRef50_A7LAU2 Cluster: Arp; n=4; Brachyspira|Rep: Arp - Treponema hyodysenteriae (Serpulina hyodysenteriae) Length = 784 Score = 35.5 bits (78), Expect = 7.5 Identities = 14/25 (56%), Positives = 21/25 (84%) Query: 178 DITPLILAAHRDSYEIIKLLLDRGA 202 D TPL++AA R+ Y+++K LLD+GA Sbjct: 244 DYTPLMIAALRNDYDMVKYLLDKGA 268 >UniRef50_A2QGH1 Cluster: Function: ankyrins link the spectrin-based membrane skeleton to the plasma membrane; n=3; Aspergillus|Rep: Function: ankyrins link the spectrin-based membrane skeleton to the plasma membrane - Aspergillus niger Length = 975 Score = 35.5 bits (78), Expect = 7.5 Identities = 17/25 (68%), Positives = 21/25 (84%) Query: 178 DITPLILAAHRDSYEIIKLLLDRGA 202 D TPLILA+ R + EIIK+LL+RGA Sbjct: 784 DQTPLILASARGNEEIIKMLLERGA 808 >UniRef50_A1C5N6 Cluster: Ankyrin repeat protein; n=1; Aspergillus clavatus|Rep: Ankyrin repeat protein - Aspergillus clavatus Length = 670 Score = 35.5 bits (78), Expect = 7.5 Identities = 19/38 (50%), Positives = 24/38 (63%), Gaps = 2/38 (5%) Query: 170 PETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEP 207 P+ F SD+TPL +AA R EI++ LLD GA P P Sbjct: 226 PDPRCF-SDLTPLCMAARRGHLEILEYLLDHGAD-PHP 261 >UniRef50_Q9HCD6 Cluster: TPR repeat, ankyrin repeat and coiled-coil-containing protein 2; n=54; Euteleostomi|Rep: TPR repeat, ankyrin repeat and coiled-coil-containing protein 2 - Homo sapiens (Human) Length = 1864 Score = 35.1 bits (77), Expect = 9.9 Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 11/81 (13%) Query: 131 RDALLHAISEEFVEAVEALLDHEERTRKPGEP---NSWEALPPETATFTSDITPLILAAH 187 + AL+ A S + E V LLD E+ + E NS+++L ETA L AA Sbjct: 866 QQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETA--------LTAAAG 917 Query: 188 RDSYEIIKLLLDRGAQLPEPH 208 R E+ +LLL++GA + +P+ Sbjct: 918 RGKLEVCRLLLEQGAAVAQPN 938 >UniRef50_Q0U645 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 369 Score = 35.1 bits (77), Expect = 9.9 Identities = 15/43 (34%), Positives = 25/43 (58%) Query: 619 PNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIK 661 P+ T P+ A W+R +T ++L WA ++DL +F+ G K Sbjct: 2 PSATYPESPAIPKWKRPTKTTESLDWADIKVIDLSTFDEPGGK 44 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.322 0.136 0.417 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,067,657,104 Number of Sequences: 1657284 Number of extensions: 42801539 Number of successful extensions: 108882 Number of sequences better than 10.0: 97 Number of HSP's better than 10.0 without gapping: 66 Number of HSP's successfully gapped in prelim test: 31 Number of HSP's that attempted gapping in prelim test: 108436 Number of HSP's gapped (non-prelim): 304 length of query: 1024 length of database: 575,637,011 effective HSP length: 108 effective length of query: 916 effective length of database: 396,650,339 effective search space: 363331710524 effective search space used: 363331710524 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.9 bits) S2: 77 (35.1 bits)
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