Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001085-TA|BGIBMGA001085-PA|IPR004729|Transient receptor
potential channel, IPR002110|Ankyrin, IPR013555|Transient receptor ion
channel II, IPR005821|Ion transport, IPR001086|Prephenate dehydratase
(1024 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC105917-1|AAI05918.1| 956|Homo sapiens TRPC4 protein protein. 691 0.0
BC105641-1|AAI05642.1| 977|Homo sapiens transient receptor pote... 691 0.0
BC104725-1|AAI04726.1| 977|Homo sapiens transient receptor pote... 691 0.0
AL354802-4|CAI15561.1| 977|Homo sapiens transient receptor pote... 691 0.0
AL354802-2|CAI15557.1| 893|Homo sapiens transient receptor pote... 691 0.0
AL138679-9|CAH70112.1| 977|Homo sapiens transient receptor pote... 691 0.0
AL138679-6|CAH70110.1| 893|Homo sapiens transient receptor pote... 691 0.0
AF421359-1|AAL24550.1| 893|Homo sapiens transient receptor pote... 691 0.0
AF421358-1|AAL24549.1| 977|Homo sapiens transient receptor pote... 691 0.0
AF175406-1|AAD51736.1| 977|Homo sapiens transient receptor pote... 691 0.0
AF063823-1|AAF22928.1| 893|Homo sapiens trp-related protein 4 t... 691 0.0
AF063822-1|AAF22927.1| 977|Homo sapiens trp-related protein 4 p... 691 0.0
AF421360-1|AAL24551.1| 982|Homo sapiens transient receptor pote... 687 0.0
AL354802-1|CAI15556.1| 836|Homo sapiens transient receptor pote... 661 0.0
AL138679-5|CAH70109.1| 836|Homo sapiens transient receptor pote... 661 0.0
AF063824-1|AAF22929.1| 836|Homo sapiens trp-related protein 4 t... 661 0.0
AL049563-3|CAI43017.1| 973|Homo sapiens transient receptor pote... 654 0.0
AF054568-1|AAF00002.1| 973|Homo sapiens transient receptor pote... 654 0.0
AB209258-1|BAD92495.1| 725|Homo sapiens transient receptor pote... 624 e-178
AL354802-3|CAI15558.1| 828|Homo sapiens transient receptor pote... 575 e-163
AL138679-7|CAH70111.1| 828|Homo sapiens transient receptor pote... 575 e-163
AF063825-1|AAF22930.1| 828|Homo sapiens trp-related protein 4 t... 575 e-163
AC005191-1|AAC24563.1| 567|Homo sapiens WUGSC:H_DJ269O05.1 prot... 511 e-144
U31110-1|AAA93251.1| 793|Homo sapiens unspliced trp-1 protein p... 491 e-138
AL354802-5|CAI15560.1| 804|Homo sapiens transient receptor pote... 446 e-124
AL138679-8|CAH70114.1| 804|Homo sapiens transient receptor pote... 446 e-124
AF421362-1|AAL24553.1| 804|Homo sapiens transient receptor pote... 446 e-124
BC105306-1|AAI05307.1| 460|Homo sapiens TRPC4 protein protein. 445 e-124
Z73903-1|CAA98108.1| 759|Homo sapiens TRPC1A protein protein. 444 e-124
X89066-1|CAA61447.1| 759|Homo sapiens TRPC1 protein protein. 444 e-124
U31110-2|AAA93252.1| 759|Homo sapiens alternatively spliced trp... 444 e-124
BC113953-1|AAI13954.1| 759|Homo sapiens TRPC1 protein protein. 444 e-124
BC112338-1|AAI12339.1| 759|Homo sapiens TRPC1 protein protein. 444 e-124
BC093660-1|AAH93660.1| 931|Homo sapiens transient receptor pote... 438 e-122
BC093658-1|AAH93658.1| 931|Homo sapiens transient receptor pote... 438 e-122
AJ271066-1|CAC01684.1| 931|Homo sapiens transient receptor pote... 438 e-122
AJ006276-1|CAA06943.1| 931|Homo sapiens transient receptor pote... 438 e-122
AF080394-1|AAC63289.2| 931|Homo sapiens transient receptor pote... 438 e-122
Y13758-1|CAA74083.1| 848|Homo sapiens transient receptor potent... 436 e-121
U47050-1|AAC51653.1| 848|Homo sapiens calcium influx channel pr... 436 e-121
BC093684-1|AAH93684.1| 848|Homo sapiens transient receptor pote... 436 e-121
BC093682-1|AAH93682.1| 848|Homo sapiens transient receptor pote... 436 e-121
AY865574-1|AAW62292.1| 921|Homo sapiens N-terminally extended t... 436 e-121
BC128185-1|AAI28186.1| 862|Homo sapiens transient receptor pote... 432 e-120
AJ272034-1|CAC03489.1| 862|Homo sapiens putative capacitative c... 432 e-120
AJ421783-1|CAD19069.1| 862|Homo sapiens short transient recepto... 429 e-119
AJ549088-1|CAD70161.1| 801|Homo sapiens transient receptor pote... 260 2e-68
AF421361-1|AAL24552.1| 323|Homo sapiens transient receptor pote... 252 5e-66
BC128186-1|AAI28187.1| 380|Homo sapiens TRPC7 protein protein. 222 6e-57
AY167927-1|AAO12125.1| 746|Homo sapiens transient receptor pote... 215 5e-55
AY167926-1|AAO12124.1| 806|Homo sapiens transient receptor pote... 215 5e-55
AJ549089-1|CAD70162.1| 807|Homo sapiens transient receptor pote... 215 5e-55
AJ271067-1|CAC01685.1| 815|Homo sapiens transient receptor pote... 214 1e-54
AJ271068-1|CAC01686.1| 876|Homo sapiens transient receptor pote... 212 5e-54
AJ549090-1|CAD70163.1| 261|Homo sapiens transient receptor pote... 142 4e-33
AJ007018-1|CAC06090.1| 157|Homo sapiens putative capacitative c... 102 6e-21
AB231779-1|BAE46900.1| 149|Homo sapiens hypothetical protein pr... 85 9e-16
X89068-1|CAA61448.1| 117|Homo sapiens TRPC3 protein protein. 81 2e-14
U40983-1|AAC50630.1| 120|Homo sapiens trp-related protein 4 pro... 78 1e-13
EF522961-1|ABP94017.1| 129|Homo sapiens TRPC1 splice variant pr... 58 2e-07
DQ012935-1|AAY22174.1| 1503|Homo sapiens transient receptor pote... 52 1e-05
BC112342-1|AAI12343.1| 1553|Homo sapiens TRPM2 protein protein. 52 1e-05
AP001754-4|BAA95563.1| 1503|Homo sapiens transient receptor pote... 52 1e-05
AJ878416-1|CAI47593.1| 1503|Homo sapiens transient receptor pote... 52 1e-05
AJ417076-1|CAD01139.1| 1449|Homo sapiens putative TRP cation cha... 52 1e-05
AB166746-1|BAD83706.1| 1289|Homo sapiens transient receptor pote... 52 1e-05
AB166745-1|BAD83705.1| 1503|Homo sapiens transient receptor pote... 52 1e-05
AB001535-1|BAA34700.1| 1503|Homo sapiens KNP3 protein. 52 1e-05
AB061779-1|BAB86335.1| 1095|Homo sapiens LTRPC6 protein. 50 3e-05
DQ139309-1|AAZ73614.1| 1104|Homo sapiens transient receptor pote... 49 1e-04
AY328400-1|AAP92167.1| 1104|Homo sapiens transient receptor pote... 49 1e-04
AY090109-1|AAM10446.1| 1104|Homo sapiens transient receptor pote... 49 1e-04
AF071787-1|AAC80000.1| 1533|Homo sapiens melastatin 1 protein. 48 2e-04
AB115502-1|BAC80204.1| 1527|Homo sapiens melastatin 1 splicing v... 48 2e-04
AB115501-1|BAC80203.1| 1533|Homo sapiens melastatin 1 protein. 48 2e-04
AB115499-1|BAC80201.1| 1533|Homo sapiens melastatin 1 protein. 48 2e-04
AB115498-1|BAC80200.1| 1533|Homo sapiens melastatin 1 protein. 48 2e-04
DQ084244-1|AAZ31363.1| 758|Homo sapiens polycystic kidney disea... 46 7e-04
BC025665-1|AAH25665.1| 805|Homo sapiens polycystic kidney disea... 46 7e-04
AL139819-2|CAH72822.1| 805|Homo sapiens polycystic kidney disea... 46 7e-04
AF153474-1|AAF28108.1| 805|Homo sapiens polycystic kidney disea... 46 7e-04
AF094827-1|AAD08695.1| 710|Homo sapiens PKD2L protein. 46 7e-04
AF053316-1|AAD51859.1| 763|Homo sapiens polycystin-2 homolog pr... 46 7e-04
AF073481-1|AAD41638.1| 805|Homo sapiens polycystin-L protein. 46 0.001
AF092170-1|AAD16101.1| 665|Homo sapiens polycystic kidney disea... 43 0.005
AC079341-5|AAY40971.1| 72|Homo sapiens unknown protein. 43 0.006
BC126342-1|AAI26343.1| 682|Homo sapiens TRPM8 protein protein. 39 0.11
AY603182-1|AAT12288.1| 846|Homo sapiens TRPM2-S protein. 38 0.14
BC093789-1|AAH93789.1| 1165|Homo sapiens transient receptor pote... 37 0.42
BC093787-1|AAH93787.1| 1165|Homo sapiens transient receptor pote... 37 0.42
AJ270996-1|CAB66342.1| 1159|Homo sapiens LTRPC5 protein protein. 37 0.42
AF177473-1|AAF26288.1| 1165|Homo sapiens MTR1 protein. 37 0.42
AY032950-1|AAK44211.1| 1865|Homo sapiens LTRPC7 protein. 36 0.56
AF346629-1|AAK19738.2| 1864|Homo sapiens channel-kinase 1 protein. 36 0.56
AF182034-1|AAF65622.1| 624|Homo sapiens polycystic kidney disea... 36 0.56
AF118125-1|AAD46478.1| 609|Homo sapiens polycystin-2-like prote... 36 0.56
U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein. 36 0.74
AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 36 0.74
AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 36 0.74
AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 36 0.74
AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat... 35 1.3
AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein. 35 1.3
BC132727-1|AAI32728.1| 1214|Homo sapiens transient receptor pote... 33 3.9
AY297046-1|AAP44475.1| 1069|Homo sapiens transient receptor pote... 33 3.9
AY297045-1|AAP44474.1| 1214|Homo sapiens transient receptor pote... 33 3.9
AY297044-1|AAP44473.1| 1040|Homo sapiens transient receptor pote... 33 3.9
AY046396-1|AAL02142.1| 1040|Homo sapiens TRP-related cation infl... 33 3.9
AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS... 33 3.9
AK000048-1|BAA90907.1| 1016|Homo sapiens protein ( Homo sapiens ... 33 3.9
AJ575813-1|CAE05941.1| 1214|Homo sapiens transient receptor pote... 33 3.9
AF497623-1|AAM18083.1| 1214|Homo sapiens cation channel TRPM4B p... 33 3.9
Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein. 33 5.2
X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein. 33 5.2
BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein pr... 33 5.2
X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2... 33 6.9
X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for ... 33 6.9
U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein. 33 6.9
M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein. 33 6.9
BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein. 33 6.9
BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS... 33 6.9
BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS... 33 6.9
AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS... 33 6.9
AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens ... 33 6.9
AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein. 33 6.9
AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein. 33 6.9
AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS... 33 6.9
AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4 var... 33 6.9
>BC105917-1|AAI05918.1| 956|Homo sapiens TRPC4 protein protein.
Length = 956
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>BC105641-1|AAI05642.1| 977|Homo sapiens transient receptor
potential 4 protein.
Length = 977
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>BC104725-1|AAI04726.1| 977|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4 protein.
Length = 977
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>AL354802-4|CAI15561.1| 977|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4 protein.
Length = 977
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>AL354802-2|CAI15557.1| 893|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4 protein.
Length = 893
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>AL138679-9|CAH70112.1| 977|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4 protein.
Length = 977
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>AL138679-6|CAH70110.1| 893|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4 protein.
Length = 893
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>AF421359-1|AAL24550.1| 893|Homo sapiens transient receptor
potential channel 4 beta splice variant protein.
Length = 893
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>AF421358-1|AAL24549.1| 977|Homo sapiens transient receptor
potential channel 4 alpha splice variant protein.
Length = 977
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>AF175406-1|AAD51736.1| 977|Homo sapiens transient receptor
potential 4 protein.
Length = 977
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>AF063823-1|AAF22928.1| 893|Homo sapiens trp-related protein 4
truncated variant beta protein.
Length = 893
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>AF063822-1|AAF22927.1| 977|Homo sapiens trp-related protein 4
protein.
Length = 977
Score = 691 bits (1708), Expect = 0.0
Identities = 370/786 (47%), Positives = 499/786 (63%), Gaps = 57/786 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRNSGMNT 816
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR S ++T
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761
Query: 817 -STANA 821
+ANA
Sbjct: 762 IQSANA 767
>AF421360-1|AAL24551.1| 982|Homo sapiens transient receptor
potential channel 4 epsilon splice variant protein.
Length = 982
Score = 687 bits (1699), Expect = 0.0
Identities = 368/791 (46%), Positives = 499/791 (63%), Gaps = 62/791 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-----------GHARAKREHMRT 761
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC G + +H R
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGVRTQHRRA 701
Query: 762 ---------IRAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRN 811
+ +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR E++ +LR
Sbjct: 702 ADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRG 761
Query: 812 SGMNT-STANA 821
S ++T +ANA
Sbjct: 762 SKLSTIQSANA 772
>AL354802-1|CAI15556.1| 836|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4 protein.
Length = 836
Score = 661 bits (1632), Expect = 0.0
Identities = 352/746 (47%), Positives = 469/746 (62%), Gaps = 55/746 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES 783
+ +MRNLV+RYV R A++
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKT 727
>AL138679-5|CAH70109.1| 836|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4 protein.
Length = 836
Score = 661 bits (1632), Expect = 0.0
Identities = 352/746 (47%), Positives = 469/746 (62%), Gaps = 55/746 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES 783
+ +MRNLV+RYV R A++
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKT 727
>AF063824-1|AAF22929.1| 836|Homo sapiens trp-related protein 4
truncated variant delta protein.
Length = 836
Score = 661 bits (1632), Expect = 0.0
Identities = 352/746 (47%), Positives = 469/746 (62%), Gaps = 55/746 (7%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSK 712
+ FT F G MFGTY +SYQLI++ AD+EWKFAR+K
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTK 641
Query: 713 LWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKREHMRTI--------- 762
LW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E TI
Sbjct: 642 LWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLR 701
Query: 763 -----RAIMRNLVRRYVTVQQRRAES 783
+ +MRNLV+RYV R A++
Sbjct: 702 RHHQYQEVMRNLVKRYVAAMIRDAKT 727
>AL049563-3|CAI43017.1| 973|Homo sapiens transient receptor
potential cation channel, subfamily C, member 5 protein.
Length = 973
Score = 654 bits (1615), Expect = 0.0
Identities = 340/772 (44%), Positives = 479/772 (62%), Gaps = 60/772 (7%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
LS EEK +L VE+GD A ++ LQ A ++N++C+DPLGRSALL+AI+
Sbjct: 29 LSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMEL 88
Query: 123 XXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPL 182
V DALL+AI +E V AVE LL + + + P + + + FT DITP+
Sbjct: 89 LLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLM--MDTQFSEFTPDITPI 146
Query: 183 ILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXX 242
+LAAH ++YEIIKLL+ + +P PH +RC C +CV S DSLRHSRSR+N Y+
Sbjct: 147 MLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASP 206
Query: 243 XXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQ 302
+DPILTAF L WEL+ LS +E+EFK EY+EL QC+ FA LLD R+S EL+
Sbjct: 207 SLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELE 266
Query: 303 ILLNHEKGASPQAPLTEPGAPERMR-LSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVP 361
I+LNH S + P++ L++LK+AIK QK+FVA PN QQLLA++WY+ P
Sbjct: 267 IILNHRDDHSEELD------PQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFP 320
Query: 362 GFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFL 421
G+RRK+ +++ + IG +FP+ S+AY+ +P S +G ++KPFIKF+CH+ASY FLF+
Sbjct: 321 GWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFM 380
Query: 422 LILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLR 481
L+LASQ I V D L +G P++VEW+IL WV G IW E+K++WD G
Sbjct: 381 LLLASQHI----------VRTD--LHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFT 428
Query: 482 EYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG 541
EY+HD WN++DF NSLY+AT++L+IV++ + ++PRE+W+ W P L++E
Sbjct: 429 EYIHDWWNLMDFAMNSLYLATISLKIVAYVK--------YNGSRPREEWEMWHPTLIAEA 480
Query: 542 LFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLW 601
LF+ +NI SSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF+ GLNQL +
Sbjct: 481 LFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYF 540
Query: 602 YY---ADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELD 658
YY A E C N + LFET+Q+LFW+ FGL++L +
Sbjct: 541 YYETRAIDEPNNCKGIRCEKQNN---------AFSTLFETLQSLFWSVFGLLNLYVTNVK 591
Query: 659 GIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYF 718
FT F G MFGTY +SYQLI++ AD+EWKFAR+KLW+SYF
Sbjct: 592 ARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYF 651
Query: 719 EEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC----GHARAKREHMRTI------------ 762
+EGGT PPPFN++PSPKS LY W C R +R ++R+
Sbjct: 652 DEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQ 711
Query: 763 --RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRN 811
+ ++RNLV+RYV R +++ G+TE++ E+KQD+S+FR E++++L N
Sbjct: 712 HYQEVIRNLVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGN 763
>AF054568-1|AAF00002.1| 973|Homo sapiens transient receptor
potential calcium channel 5 protein.
Length = 973
Score = 654 bits (1615), Expect = 0.0
Identities = 340/772 (44%), Positives = 479/772 (62%), Gaps = 60/772 (7%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
LS EEK +L VE+GD A ++ LQ A ++N++C+DPLGRSALL+AI+
Sbjct: 29 LSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMEL 88
Query: 123 XXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPL 182
V DALL+AI +E V AVE LL + + + P + + + FT DITP+
Sbjct: 89 LLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLM--MDTQFSEFTPDITPI 146
Query: 183 ILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXX 242
+LAAH ++YEIIKLL+ + +P PH +RC C +CV S DSLRHSRSR+N Y+
Sbjct: 147 MLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASP 206
Query: 243 XXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQ 302
+DPILTAF L WEL+ LS +E+EFK EY+EL QC+ FA LLD R+S EL+
Sbjct: 207 SLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELE 266
Query: 303 ILLNHEKGASPQAPLTEPGAPERMR-LSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVP 361
I+LNH S + P++ L++LK+AIK QK+FVA PN QQLLA++WY+ P
Sbjct: 267 IILNHRDDHSEELD------PQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFP 320
Query: 362 GFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFL 421
G+RRK+ +++ + IG +FP+ S+AY+ +P S +G ++KPFIKF+CH+ASY FLF+
Sbjct: 321 GWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFM 380
Query: 422 LILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLR 481
L+LASQ I V D L +G P++VEW+IL WV G IW E+K++WD G
Sbjct: 381 LLLASQHI----------VRTD--LHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFT 428
Query: 482 EYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG 541
EY+HD WN++DF NSLY+AT++L+IV++ + ++PRE+W+ W P L++E
Sbjct: 429 EYIHDWWNLMDFAMNSLYLATISLKIVAYVK--------YNGSRPREEWEMWHPTLIAEA 480
Query: 542 LFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLW 601
LF+ +NI SSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF+ GLNQL +
Sbjct: 481 LFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYF 540
Query: 602 YY---ADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELD 658
YY A E C N + LFET+Q+LFW+ FGL++L +
Sbjct: 541 YYETRAIDEPNNCKGIRCEKQNN---------AFSTLFETLQSLFWSVFGLLNLYVTNVK 591
Query: 659 GIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYF 718
FT F G MFGTY +SYQLI++ AD+EWKFAR+KLW+SYF
Sbjct: 592 ARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYF 651
Query: 719 EEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC----GHARAKREHMRTI------------ 762
+EGGT PPPFN++PSPKS LY W C R +R ++R+
Sbjct: 652 DEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQ 711
Query: 763 --RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFRCELVEILRN 811
+ ++RNLV+RYV R +++ G+TE++ E+KQD+S+FR E++++L N
Sbjct: 712 HYQEVIRNLVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGN 763
>AB209258-1|BAD92495.1| 725|Homo sapiens transient receptor
potential cation channel, subfamily C, member 5 variant
protein.
Length = 725
Score = 624 bits (1541), Expect = e-178
Identities = 316/691 (45%), Positives = 434/691 (62%), Gaps = 41/691 (5%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
LS EEK +L VE+GD A ++ LQ A ++N++C+DPLGRSALL+AI+
Sbjct: 30 LSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMEL 89
Query: 123 XXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPL 182
V DALL+AI +E V AVE LL + + + P + + + FT DITP+
Sbjct: 90 LLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLM--MDTQFSEFTPDITPI 147
Query: 183 ILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXX 242
+LAAH ++YEIIKLL+ + +P PH +RC C +CV S DSLRHSRSR+N Y+
Sbjct: 148 MLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASP 207
Query: 243 XXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQ 302
+DPILTAF L WEL+ LS +E+EFK EY+EL QC+ FA LLD R+S EL+
Sbjct: 208 SLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELE 267
Query: 303 ILLNHEKGASPQAPLTEPGAPERMR-LSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVP 361
I+LNH S + P++ L++LK+AIK QK+FVA PN QQLLA++WY+ P
Sbjct: 268 IILNHRDDHSEELD------PQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFP 321
Query: 362 GFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFL 421
G+RRK+ +++ + IG +FP+ S+AY+ +P S +G ++KPFIKF+CH+ASY FLF+
Sbjct: 322 GWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFM 381
Query: 422 LILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLR 481
L+LASQ I V D L +G P++VEW+IL WV G IW E+K++WD G
Sbjct: 382 LLLASQHI----------VRTD--LHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFT 429
Query: 482 EYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG 541
EY+HD WN++DF NSLY+AT++L+IV++ + ++PRE+W+ W P L++E
Sbjct: 430 EYIHDWWNLMDFAMNSLYLATISLKIVAYVK--------YNGSRPREEWEMWHPTLIAEA 481
Query: 542 LFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLW 601
LF+ +NI SSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF+ GLNQL +
Sbjct: 482 LFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYF 541
Query: 602 YY---ADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELD 658
YY A E C N + LFET+Q+LFW+ FGL++L +
Sbjct: 542 YYETRAIDEPNNCKGIRCEKQNN---------AFSTLFETLQSLFWSVFGLLNLYVTNVK 592
Query: 659 GIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYF 718
FT F G MFGTY +SYQLI++ AD+EWKFAR+KLW+SYF
Sbjct: 593 ARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYF 652
Query: 719 EEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC 749
+EGGT PPPFN++PSPKS LY W C
Sbjct: 653 DEGGTLPPPFNIIPSPKSFLYLGNWFNNTFC 683
>AL354802-3|CAI15558.1| 828|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4 protein.
Length = 828
Score = 575 bits (1420), Expect = e-163
Identities = 305/650 (46%), Positives = 410/650 (63%), Gaps = 40/650 (6%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERA 702
+ FT F G MFGTY +SYQLI+ RA
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIARRA 631
Score = 56.0 bits (129), Expect = 6e-07
Identities = 33/84 (39%), Positives = 55/84 (65%), Gaps = 6/84 (7%)
Query: 740 AWRWLQRRLCGHARAKREHMRTIRAIMRNLVRRYVTVQQRRAESG-GVTEDDVNEIKQDV 798
+++ + RR + R R H + +MRNLV+RYV R A++ G+TE++ E+KQD+
Sbjct: 623 SYQLIARRAADNLR--RHHQ--YQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDI 678
Query: 799 SAFRCELVEILRNSGMNT-STANA 821
S+FR E++ +LR S ++T +ANA
Sbjct: 679 SSFRFEVLGLLRGSKLSTIQSANA 702
>AL138679-7|CAH70111.1| 828|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4 protein.
Length = 828
Score = 575 bits (1420), Expect = e-163
Identities = 305/650 (46%), Positives = 410/650 (63%), Gaps = 40/650 (6%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERA 702
+ FT F G MFGTY +SYQLI+ RA
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIARRA 631
Score = 56.0 bits (129), Expect = 6e-07
Identities = 33/84 (39%), Positives = 55/84 (65%), Gaps = 6/84 (7%)
Query: 740 AWRWLQRRLCGHARAKREHMRTIRAIMRNLVRRYVTVQQRRAESG-GVTEDDVNEIKQDV 798
+++ + RR + R R H + +MRNLV+RYV R A++ G+TE++ E+KQD+
Sbjct: 623 SYQLIARRAADNLR--RHHQ--YQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDI 678
Query: 799 SAFRCELVEILRNSGMNT-STANA 821
S+FR E++ +LR S ++T +ANA
Sbjct: 679 SSFRFEVLGLLRGSKLSTIQSANA 702
>AF063825-1|AAF22930.1| 828|Homo sapiens trp-related protein 4
truncated variant gamma protein.
Length = 828
Score = 575 bits (1420), Expect = e-163
Identities = 305/650 (46%), Positives = 410/650 (63%), Gaps = 40/650 (6%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDA 532
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A+ PRE WD
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFV---KYSAL-----NPRESWDM 470
Query: 533 WDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAF 592
W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF
Sbjct: 471 WHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAF 530
Query: 593 SCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDL 652
+ GLNQL +YY + + C N + LFET+Q+LFW+ FGL++L
Sbjct: 531 ANGLNQLYFYYEETKGLTCKGIRCEKQNN---------AFSTLFETLQSLFWSIFGLINL 581
Query: 653 DSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERA 702
+ FT F G MFGTY +SYQLI+ RA
Sbjct: 582 YVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIARRA 631
Score = 56.0 bits (129), Expect = 6e-07
Identities = 33/84 (39%), Positives = 55/84 (65%), Gaps = 6/84 (7%)
Query: 740 AWRWLQRRLCGHARAKREHMRTIRAIMRNLVRRYVTVQQRRAESG-GVTEDDVNEIKQDV 798
+++ + RR + R R H + +MRNLV+RYV R A++ G+TE++ E+KQD+
Sbjct: 623 SYQLIARRAADNLR--RHHQ--YQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDI 678
Query: 799 SAFRCELVEILRNSGMNT-STANA 821
S+FR E++ +LR S ++T +ANA
Sbjct: 679 SSFRFEVLGLLRGSKLSTIQSANA 702
>AC005191-1|AAC24563.1| 567|Homo sapiens WUGSC:H_DJ269O05.1
protein.
Length = 567
Score = 511 bits (1260), Expect = e-144
Identities = 254/542 (46%), Positives = 356/542 (65%), Gaps = 29/542 (5%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
LS EEK +L VE+GD A ++ LQ A ++N++C+DPLGRSALL+AI+
Sbjct: 29 LSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMEL 88
Query: 123 XXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPL 182
V DALL+AI +E V AVE LL + + + P + + + FT DITP+
Sbjct: 89 LLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLM--MDTQFSEFTPDITPI 146
Query: 183 ILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXX 242
+LAAH ++YEIIKLL+ + +P PH +RC C +CV S DSLRHSRSR+N Y+
Sbjct: 147 MLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASP 206
Query: 243 XXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQ 302
+DPILTAF L WEL+ LS +E+EFK EY+EL QC+ FA LLD R+S EL+
Sbjct: 207 SLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELE 266
Query: 303 ILLNHEKGASPQAPLTEPGAPERMR-LSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVP 361
I+LNH S + P++ L++LK+AIK QK+FVA PN QQLLA++WY+ P
Sbjct: 267 IILNHRDDHSEELD------PQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFP 320
Query: 362 GFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFL 421
G+RRK+ +++ + IG +FP+ S+AY+ +P S +G ++KPFIKF+CH+ASY FLF+
Sbjct: 321 GWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFM 380
Query: 422 LILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLR 481
L+LASQ I V D L +G P++VEW+IL WV G IW E+K++WD G
Sbjct: 381 LLLASQHI----------VRTD--LHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFT 428
Query: 482 EYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG 541
EY+HD WN++DF NSLY+AT++L+IV++ + ++PRE+W+ W P L++E
Sbjct: 429 EYIHDWWNLMDFAMNSLYLATISLKIVAYVK--------YNGSRPREEWEMWHPTLIAEA 480
Query: 542 LFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLW 601
LF+ +NI SSL+L+ +F+ N HLGPLQ+SL RM+LDILKF + LV+ AF+ GLNQL +
Sbjct: 481 LFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYF 540
Query: 602 YY 603
YY
Sbjct: 541 YY 542
>U31110-1|AAA93251.1| 793|Homo sapiens unspliced trp-1 protein
protein.
Length = 793
Score = 491 bits (1211), Expect = e-138
Identities = 282/768 (36%), Positives = 434/768 (56%), Gaps = 55/768 (7%)
Query: 64 SLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXXX 123
+L EK +LL ++GD +++L+ +G +N++CVD LGR+A+ + I+
Sbjct: 45 TLNEKLFLLACDKGDYYMVKKILEE-NSSGDLNINCVDVLGRNAVTITIENENLDILQLL 103
Query: 124 XXFGVETRDALLHAISEEFVEAVEALLDHE-ERTRKPGEPNSWEALP-PETATFTSDITP 181
+G ++ DALL AI E V AV+ LL+H +R+ +P E + PE +T T D+ P
Sbjct: 104 LDYGCQSADALLVAIDSEVVGAVDILLNHRPKRSSRPTIVKLMERIQNPEYST-TMDVAP 162
Query: 182 LILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXX 241
+ILAAHR++YEI+ +LL + LP+PH V C C C ++DSLRHSR R++ YR
Sbjct: 163 VILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLAS 222
Query: 242 XXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNEL 301
+DPIL AFELS +L+ LS +E EF+ +Y+EL QC+ FA LL R S EL
Sbjct: 223 PALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSREL 282
Query: 302 QILLNHEKGASPQAPLTEPG-APERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESV 360
+++LNH S PL + G ERM LSRLKLAIK QK+FV+ N QQ L ++W+ +
Sbjct: 283 EVILNH---TSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQM 339
Query: 361 PGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLF 420
G+RRK + ++ +G +P+ SL Y+ AP S GR + PF+KF+ H ASYF FL
Sbjct: 340 SGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLL 399
Query: 421 LLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGL 480
LL L S V +++ + G +++L++ W+ G+IWS++K+LW GL
Sbjct: 400 LLNLYSL------------VYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGL 447
Query: 481 REYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSE 540
+++ + N + FV NSLY+AT AL++V+H + + A R+ WDA+ P L++E
Sbjct: 448 EDFLEESRNQLSFVMNSLYLATFALKVVAHNKF-HDFA-------DRKDWDAFHPTLVAE 499
Query: 541 GLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL 600
GLF+ AN+ S L+L ++++ + LGPLQ+S+ +M+ D KF + +LV+F+F+ GL QL
Sbjct: 500 GLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLY 559
Query: 601 -WYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSF--EL 657
Y E+K C G + + + T LFW F L + F
Sbjct: 560 DKGYTSKEQKDCV--------GIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRF 611
Query: 658 DGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISY 717
+ F G ++ GTY S+QLI+ D EWKFAR+KLW+SY
Sbjct: 612 SYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSY 671
Query: 718 FEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGH---ARAKREHM------------RTI 762
F++ T PPPFN++PSPK++ Y L + +C H + KR++
Sbjct: 672 FDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENY 731
Query: 763 RAIMRNLVRRYVT-VQQRRAESGGVTEDDVNEIKQDVSAFRCELVEIL 809
+ +M LV RY+T ++Q+ + T +++NE++QD+S FR E+ ++L
Sbjct: 732 QKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLL 779
>AL354802-5|CAI15560.1| 804|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4 protein.
Length = 804
Score = 446 bits (1099), Expect = e-124
Identities = 233/500 (46%), Positives = 319/500 (63%), Gaps = 46/500 (9%)
Query: 339 QKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVG 398
+K+FVA PN QQLLAS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G
Sbjct: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183
Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEW 458
+RKPFIKF+CH+ASY FLFLL+LASQ I+ + L+R+G P+IVEW
Sbjct: 184 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSD------------LNRQGPPPTIVEW 231
Query: 459 LILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMA 518
+IL WV G IW E+KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A
Sbjct: 232 MILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS---A 288
Query: 519 MGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDI 578
+ PRE WD W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDI
Sbjct: 289 LN-----PRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDI 343
Query: 579 LKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFET 638
LKF + LV+ AF+ GLNQL +YY + + C N + LFET
Sbjct: 344 LKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNA---------FSTLFET 394
Query: 639 MQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLI 698
+Q+LFW+ FGL++L + FT F G MFGTY +SYQLI
Sbjct: 395 LQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLI 454
Query: 699 SERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKRE 757
++ AD+EWKFAR+KLW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E
Sbjct: 455 ADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE 514
Query: 758 HMRTI--------------RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFR 802
TI + +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR
Sbjct: 515 SFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFR 574
Query: 803 CELVEILRNSGMNT-STANA 821
E++ +LR S ++T +ANA
Sbjct: 575 FEVLGLLRGSKLSTIQSANA 594
Score = 83.0 bits (196), Expect = 5e-15
Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 3/102 (2%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEE 154
+ F V DALLHAI +E V AVE LL+H++
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
>AL138679-8|CAH70114.1| 804|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4 protein.
Length = 804
Score = 446 bits (1099), Expect = e-124
Identities = 233/500 (46%), Positives = 319/500 (63%), Gaps = 46/500 (9%)
Query: 339 QKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVG 398
+K+FVA PN QQLLAS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G
Sbjct: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183
Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEW 458
+RKPFIKF+CH+ASY FLFLL+LASQ I+ + L+R+G P+IVEW
Sbjct: 184 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSD------------LNRQGPPPTIVEW 231
Query: 459 LILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMA 518
+IL WV G IW E+KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A
Sbjct: 232 MILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS---A 288
Query: 519 MGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDI 578
+ PRE WD W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDI
Sbjct: 289 LN-----PRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDI 343
Query: 579 LKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFET 638
LKF + LV+ AF+ GLNQL +YY + + C N + LFET
Sbjct: 344 LKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNA---------FSTLFET 394
Query: 639 MQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLI 698
+Q+LFW+ FGL++L + FT F G MFGTY +SYQLI
Sbjct: 395 LQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLI 454
Query: 699 SERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKRE 757
++ AD+EWKFAR+KLW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E
Sbjct: 455 ADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE 514
Query: 758 HMRTI--------------RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFR 802
TI + +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR
Sbjct: 515 SFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFR 574
Query: 803 CELVEILRNSGMNT-STANA 821
E++ +LR S ++T +ANA
Sbjct: 575 FEVLGLLRGSKLSTIQSANA 594
Score = 83.0 bits (196), Expect = 5e-15
Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 3/102 (2%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEE 154
+ F V DALLHAI +E V AVE LL+H++
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
>AF421362-1|AAL24553.1| 804|Homo sapiens transient receptor
potential channel 4 zeta splice variant protein.
Length = 804
Score = 446 bits (1099), Expect = e-124
Identities = 233/500 (46%), Positives = 319/500 (63%), Gaps = 46/500 (9%)
Query: 339 QKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVG 398
+K+FVA PN QQLLAS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G
Sbjct: 124 EKQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLG 183
Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEW 458
+RKPFIKF+CH+ASY FLFLL+LASQ I+ + L+R+G P+IVEW
Sbjct: 184 LFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSD------------LNRQGPPPTIVEW 231
Query: 459 LILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMA 518
+IL WV G IW E+KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ + A
Sbjct: 232 MILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS---A 288
Query: 519 MGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDI 578
+ PRE WD W P L++E LF+ ANIFSSL+L+ +F+ N HLGPLQ+SL RM+LDI
Sbjct: 289 LN-----PRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDI 343
Query: 579 LKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFET 638
LKF + LV+ AF+ GLNQL +YY + + C N + LFET
Sbjct: 344 LKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNA---------FSTLFET 394
Query: 639 MQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLI 698
+Q+LFW+ FGL++L + FT F G MFGTY +SYQLI
Sbjct: 395 LQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLI 454
Query: 699 SERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLC-GHARAKRE 757
++ AD+EWKFAR+KLW+SYFEEGGT P PFNV+PSPKSL Y +W+ LC R K E
Sbjct: 455 ADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPE 514
Query: 758 HMRTI--------------RAIMRNLVRRYVTVQQRRAES-GGVTEDDVNEIKQDVSAFR 802
TI + +MRNLV+RYV R A++ G+TE++ E+KQD+S+FR
Sbjct: 515 SFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFR 574
Query: 803 CELVEILRNSGMNT-STANA 821
E++ +LR S ++T +ANA
Sbjct: 575 FEVLGLLRGSKLSTIQSANA 594
Score = 83.0 bits (196), Expect = 5e-15
Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 3/102 (2%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEE 154
+ F V DALLHAI +E V AVE LL+H++
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 120
>BC105306-1|AAI05307.1| 460|Homo sapiens TRPC4 protein protein.
Length = 460
Score = 445 bits (1097), Expect = e-124
Identities = 227/461 (49%), Positives = 307/461 (66%), Gaps = 23/461 (4%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQLL 352
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+FVA PN QQLL
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKEFVAQPNCQQLL 310
Query: 353 ASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHS 412
AS WY+ PG+RR++ ++ IG +FP++S+ Y+ AP S +G +RKPFIKF+CH+
Sbjct: 311 ASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHT 370
Query: 413 ASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEV 472
ASY FLFLL+LASQ I+ + L+R+G P+IVEW+IL WV G IW E+
Sbjct: 371 ASYLTFLFLLLLASQHIDRS------------DLNRQGPPPTIVEWMILPWVLGFIWGEI 418
Query: 473 KQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513
KQ+WD GL++Y+HD WN++DFV NSLY+AT++L+IV+ +V
Sbjct: 419 KQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKV 459
>Z73903-1|CAA98108.1| 759|Homo sapiens TRPC1A protein protein.
Length = 759
Score = 444 bits (1094), Expect = e-124
Identities = 270/766 (35%), Positives = 417/766 (54%), Gaps = 85/766 (11%)
Query: 64 SLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXXX 123
+L EK +LL ++GD +++L+ +G +N++CVD LG
Sbjct: 45 TLNEKLFLLACDKGDYYMVKKILEE-NSSGDLNINCVDVLG------------------- 84
Query: 124 XXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLI 183
R+A+ I E ++ ++ LLD+ + N PE +T T D+ P+I
Sbjct: 85 -------RNAVTITIENENLDILQLLLDYGCQKLMERIQN------PEYST-TMDVAPVI 130
Query: 184 LAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXX 243
LAAHR++YEI+ +LL + LP+PH V C C C ++DSLRHSR R++ YR
Sbjct: 131 LAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPA 190
Query: 244 XXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQI 303
+DPIL AFELS +L+ LS +E EF+ +Y+EL QC+ FA LL R S EL++
Sbjct: 191 LIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEV 250
Query: 304 LLNHEKGASPQAPLTEPG-APERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPG 362
+LNH S PL + G ERM LSRLKLAIK QK+FV+ N QQ L ++W+ + G
Sbjct: 251 ILNH---TSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSG 307
Query: 363 FRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLL 422
+RRK + ++ +G +P+ SL Y+ AP S GR + PF+KF+ H ASYF FL LL
Sbjct: 308 YRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLL 367
Query: 423 ILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLRE 482
L S V +++ + G +++L++ W+ G+IWS++K+LW GL +
Sbjct: 368 NLYSL------------VYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLED 415
Query: 483 YVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGL 542
++ + N + FV NSLY+AT AL++V+H + + A R+ WDA+ P L++EGL
Sbjct: 416 FLEESRNQLSFVMNSLYLATFALKVVAHNKF-HDFA-------DRKDWDAFHPTLVAEGL 467
Query: 543 FSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL-W 601
F+ AN+ S L+L ++++ + LGPLQ+S+ +M+ D KF + +LV+F+F+ GL QL
Sbjct: 468 FAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDK 527
Query: 602 YYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSF--ELDG 659
Y E+K C G + + + T LFW F L + F
Sbjct: 528 GYTSKEQKDCV--------GIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSY 579
Query: 660 IKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFE 719
+ F G ++ GTY S+QLI+ D EWKFAR+KLW+SYF+
Sbjct: 580 GEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFD 639
Query: 720 EGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGH---ARAKREHM------------RTIRA 764
+ T PPPFN++PSPK++ Y L + +C H + KR++ +
Sbjct: 640 DKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQK 699
Query: 765 IMRNLVRRYVT-VQQRRAESGGVTEDDVNEIKQDVSAFRCELVEIL 809
+M LV RY+T ++Q+ + T +++NE++QD+S FR E+ ++L
Sbjct: 700 VMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLL 745
>X89066-1|CAA61447.1| 759|Homo sapiens TRPC1 protein protein.
Length = 759
Score = 444 bits (1094), Expect = e-124
Identities = 270/766 (35%), Positives = 417/766 (54%), Gaps = 85/766 (11%)
Query: 64 SLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXXX 123
+L EK +LL ++GD +++L+ +G +N++CVD LG
Sbjct: 45 TLNEKLFLLACDKGDYYMVKKILEE-NSSGDLNINCVDVLG------------------- 84
Query: 124 XXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLI 183
R+A+ I E ++ ++ LLD+ + N PE +T T D+ P+I
Sbjct: 85 -------RNAVTITIENENLDILQLLLDYGCQKLMERIQN------PEYST-TMDVAPVI 130
Query: 184 LAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXX 243
LAAHR++YEI+ +LL + LP+PH V C C C ++DSLRHSR R++ YR
Sbjct: 131 LAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPA 190
Query: 244 XXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQI 303
+DPIL AFELS +L+ LS +E EF+ +Y+EL QC+ FA LL R S EL++
Sbjct: 191 LIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEV 250
Query: 304 LLNHEKGASPQAPLTEPG-APERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPG 362
+LNH S PL + G ERM LSRLKLAIK QK+FV+ N QQ L ++W+ + G
Sbjct: 251 ILNH---TSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSG 307
Query: 363 FRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLL 422
+RRK + ++ +G +P+ SL Y+ AP S GR + PF+KF+ H ASYF FL LL
Sbjct: 308 YRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLL 367
Query: 423 ILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLRE 482
L S V +++ + G +++L++ W+ G+IWS++K+LW GL +
Sbjct: 368 NLYSL------------VYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLED 415
Query: 483 YVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGL 542
++ + N + FV NSLY+AT AL++V+H + + A R+ WDA+ P L++EGL
Sbjct: 416 FLEESRNQLSFVMNSLYLATFALKVVAHNKF-HDFA-------DRKDWDAFHPTLVAEGL 467
Query: 543 FSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL-W 601
F+ AN+ S L+L ++++ + LGPLQ+S+ +M+ D KF + +LV+F+F+ GL QL
Sbjct: 468 FAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDK 527
Query: 602 YYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSF--ELDG 659
Y E+K C G + + + T LFW F L + F
Sbjct: 528 GYTSKEQKDCV--------GIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSY 579
Query: 660 IKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFE 719
+ F G ++ GTY S+QLI+ D EWKFAR+KLW+SYF+
Sbjct: 580 GEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFD 639
Query: 720 EGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGH---ARAKREHM------------RTIRA 764
+ T PPPFN++PSPK++ Y L + +C H + KR++ +
Sbjct: 640 DKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQK 699
Query: 765 IMRNLVRRYVT-VQQRRAESGGVTEDDVNEIKQDVSAFRCELVEIL 809
+M LV RY+T ++Q+ + T +++NE++QD+S FR E+ ++L
Sbjct: 700 VMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLL 745
>U31110-2|AAA93252.1| 759|Homo sapiens alternatively spliced trp-1
protein protein.
Length = 759
Score = 444 bits (1094), Expect = e-124
Identities = 270/766 (35%), Positives = 417/766 (54%), Gaps = 85/766 (11%)
Query: 64 SLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXXX 123
+L EK +LL ++GD +++L+ +G +N++CVD LG
Sbjct: 45 TLNEKLFLLACDKGDYYMVKKILEE-NSSGDLNINCVDVLG------------------- 84
Query: 124 XXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLI 183
R+A+ I E ++ ++ LLD+ + N PE +T T D+ P+I
Sbjct: 85 -------RNAVTITIENENLDILQLLLDYGCQKLMERIQN------PEYST-TMDVAPVI 130
Query: 184 LAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXX 243
LAAHR++YEI+ +LL + LP+PH V C C C ++DSLRHSR R++ YR
Sbjct: 131 LAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPA 190
Query: 244 XXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQI 303
+DPIL AFELS +L+ LS +E EF+ +Y+EL QC+ FA LL R S EL++
Sbjct: 191 LIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEV 250
Query: 304 LLNHEKGASPQAPLTEPG-APERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPG 362
+LNH S PL + G ERM LSRLKLAIK QK+FV+ N QQ L ++W+ + G
Sbjct: 251 ILNH---TSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSG 307
Query: 363 FRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLL 422
+RRK + ++ +G +P+ SL Y+ AP S GR + PF+KF+ H ASYF FL LL
Sbjct: 308 YRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLL 367
Query: 423 ILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLRE 482
L S V +++ + G +++L++ W+ G+IWS++K+LW GL +
Sbjct: 368 NLYSL------------VYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLED 415
Query: 483 YVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGL 542
++ + N + FV NSLY+AT AL++V+H + + A R+ WDA+ P L++EGL
Sbjct: 416 FLEESRNQLSFVMNSLYLATFALKVVAHNKF-HDFA-------DRKDWDAFHPTLVAEGL 467
Query: 543 FSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL-W 601
F+ AN+ S L+L ++++ + LGPLQ+S+ +M+ D KF + +LV+F+F+ GL QL
Sbjct: 468 FAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDK 527
Query: 602 YYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSF--ELDG 659
Y E+K C G + + + T LFW F L + F
Sbjct: 528 GYTSKEQKDCV--------GIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSY 579
Query: 660 IKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFE 719
+ F G ++ GTY S+QLI+ D EWKFAR+KLW+SYF+
Sbjct: 580 GEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFD 639
Query: 720 EGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGH---ARAKREHM------------RTIRA 764
+ T PPPFN++PSPK++ Y L + +C H + KR++ +
Sbjct: 640 DKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQK 699
Query: 765 IMRNLVRRYVT-VQQRRAESGGVTEDDVNEIKQDVSAFRCELVEIL 809
+M LV RY+T ++Q+ + T +++NE++QD+S FR E+ ++L
Sbjct: 700 VMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLL 745
>BC113953-1|AAI13954.1| 759|Homo sapiens TRPC1 protein protein.
Length = 759
Score = 444 bits (1094), Expect = e-124
Identities = 270/766 (35%), Positives = 417/766 (54%), Gaps = 85/766 (11%)
Query: 64 SLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXXX 123
+L EK +LL ++GD +++L+ +G +N++CVD LG
Sbjct: 45 TLNEKLFLLACDKGDYYMVKKILEE-NSSGDLNINCVDVLG------------------- 84
Query: 124 XXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLI 183
R+A+ I E ++ ++ LLD+ + N PE +T T D+ P+I
Sbjct: 85 -------RNAVTITIENENLDILQLLLDYGCQKLMERIQN------PEYST-TMDVAPVI 130
Query: 184 LAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXX 243
LAAHR++YEI+ +LL + LP+PH V C C C ++DSLRHSR R++ YR
Sbjct: 131 LAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPA 190
Query: 244 XXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQI 303
+DPIL AFELS +L+ LS +E EF+ +Y+EL QC+ FA LL R S EL++
Sbjct: 191 LIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEV 250
Query: 304 LLNHEKGASPQAPLTEPG-APERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPG 362
+LNH S PL + G ERM LSRLKLAIK QK+FV+ N QQ L ++W+ + G
Sbjct: 251 ILNH---TSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSG 307
Query: 363 FRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLL 422
+RRK + ++ +G +P+ SL Y+ AP S GR + PF+KF+ H ASYF FL LL
Sbjct: 308 YRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLL 367
Query: 423 ILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLRE 482
L S V +++ + G +++L++ W+ G+IWS++K+LW GL +
Sbjct: 368 NLYSL------------VYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLED 415
Query: 483 YVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGL 542
++ + N + FV NSLY+AT AL++V+H + + A R+ WDA+ P L++EGL
Sbjct: 416 FLEESRNQLSFVMNSLYLATFALKVVAHNKF-HDFA-------DRKDWDAFHPTLVAEGL 467
Query: 543 FSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL-W 601
F+ AN+ S L+L ++++ + LGPLQ+S+ +M+ D KF + +LV+F+F+ GL QL
Sbjct: 468 FAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDK 527
Query: 602 YYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSF--ELDG 659
Y E+K C G + + + T LFW F L + F
Sbjct: 528 GYTSKEQKDCV--------GIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSY 579
Query: 660 IKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFE 719
+ F G ++ GTY S+QLI+ D EWKFAR+KLW+SYF+
Sbjct: 580 GEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFD 639
Query: 720 EGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGH---ARAKREHM------------RTIRA 764
+ T PPPFN++PSPK++ Y L + +C H + KR++ +
Sbjct: 640 DKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQK 699
Query: 765 IMRNLVRRYVT-VQQRRAESGGVTEDDVNEIKQDVSAFRCELVEIL 809
+M LV RY+T ++Q+ + T +++NE++QD+S FR E+ ++L
Sbjct: 700 VMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLL 745
>BC112338-1|AAI12339.1| 759|Homo sapiens TRPC1 protein protein.
Length = 759
Score = 444 bits (1094), Expect = e-124
Identities = 270/766 (35%), Positives = 417/766 (54%), Gaps = 85/766 (11%)
Query: 64 SLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXXX 123
+L EK +LL ++GD +++L+ +G +N++CVD LG
Sbjct: 45 TLNEKLFLLACDKGDYYMVKKILEE-NSSGDLNINCVDVLG------------------- 84
Query: 124 XXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPETATFTSDITPLI 183
R+A+ I E ++ ++ LLD+ + N PE +T T D+ P+I
Sbjct: 85 -------RNAVTITIENENLDILQLLLDYGCQKLMERIQN------PEYST-TMDVAPVI 130
Query: 184 LAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSRINAYRXXXXXX 243
LAAHR++YEI+ +LL + LP+PH V C C C ++DSLRHSR R++ YR
Sbjct: 131 LAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPA 190
Query: 244 XXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALLDHTRTSNELQI 303
+DPIL AFELS +L+ LS +E EF+ +Y+EL QC+ FA LL R S EL++
Sbjct: 191 LIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEV 250
Query: 304 LLNHEKGASPQAPLTEPG-APERMRLSRLKLAIKLRQKKFVAHPNVQQLLASIWYESVPG 362
+LNH S PL + G ERM LSRLKLAIK QK+FV+ N QQ L ++W+ + G
Sbjct: 251 ILNH---TSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSG 307
Query: 363 FRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLL 422
+RRK + ++ +G +P+ SL Y+ AP S GR + PF+KF+ H ASYF FL LL
Sbjct: 308 YRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLL 367
Query: 423 ILASQRIETAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSGLIWSEVKQLWDMGLRE 482
L S V +++ + G +++L++ W+ G+IWS++K+LW GL +
Sbjct: 368 NLYSL------------VYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLED 415
Query: 483 YVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGL 542
++ + N + FV NSLY+AT AL++V+H + + A R+ WDA+ P L++EGL
Sbjct: 416 FLEESRNQLSFVMNSLYLATFALKVVAHNKF-HDFA-------DRKDWDAFHPTLVAEGL 467
Query: 543 FSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL-W 601
F+ AN+ S L+L ++++ + LGPLQ+S+ +M+ D KF + +LV+F+F+ GL QL
Sbjct: 468 FAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDK 527
Query: 602 YYADMEKKRCTVGTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSF--ELDG 659
Y E+K C G + + + T LFW F L + F
Sbjct: 528 GYTSKEQKDCV--------GIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSY 579
Query: 660 IKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFE 719
+ F G ++ GTY S+QLI+ D EWKFAR+KLW+SYF+
Sbjct: 580 GEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFD 639
Query: 720 EGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGH---ARAKREHM------------RTIRA 764
+ T PPPFN++PSPK++ Y L + +C H + KR++ +
Sbjct: 640 DKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQK 699
Query: 765 IMRNLVRRYVT-VQQRRAESGGVTEDDVNEIKQDVSAFRCELVEIL 809
+M LV RY+T ++Q+ + T +++NE++QD+S FR E+ ++L
Sbjct: 700 VMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLL 745
>BC093660-1|AAH93660.1| 931|Homo sapiens transient receptor
potential cation channel, subfamily C, member 6 protein.
Length = 931
Score = 438 bits (1080), Expect = e-122
Identities = 262/733 (35%), Positives = 395/733 (53%), Gaps = 68/733 (9%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
LS+EE+++L E G++ R++L+ +NV+CVD +G++AL +A+
Sbjct: 95 LSIEEERFLDAAEYGNIPVVRKMLEECHS---LNVNCVDYMGQNALQLAVANEHLEITEL 151
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDHE---ERTRKPGEPNSWE-------ALPP 170
+R DALL AIS+ +V VEA+L H E R P+ E A
Sbjct: 152 LLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDE 211
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ D+TP+ILAAH YEI+ LL +GA++ PHD C C+DC + ++ DS HSR
Sbjct: 212 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSR 271
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SRINAY+ +DP++TA ELS EL L+ +E EFK +Y++L +QC++F
Sbjct: 272 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVG 331
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
LLD R + E++ +LN + + G R LSRLKLAIK KKFVAHPN QQ
Sbjct: 332 LLDLCRNTEEVEAILNGD------VETLQSGDHGRPNLSRLKLAIKYEVKKFVAHPNCQQ 385
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L SIWYE++ G R++ M ++ ++ + P +L Y AP S +G+ +R PF+KF+
Sbjct: 386 QLLSIWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWFAPCSKMGKIMRGPFMKFVA 445
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSG 466
H+AS+ +FL LL++ A+ R E P D + + + S S +E LI++WV G
Sbjct: 446 HAASFTIFLGLLVMNAADRFEGTKLLPNETSTD-NAKQLFRMKTSCFSWMEMLIISWVIG 504
Query: 467 LIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR----------- 515
+IW+E K++W G +EY+ ++WN++DF +++ A+ R ++ + +
Sbjct: 505 MIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTL 564
Query: 516 ----EMAMG---LQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQ 568
++ +G +N R KWD DP ++SEGL++ A + S ++ YI N GPLQ
Sbjct: 565 KDLTKVTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQ 624
Query: 569 VSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDA 628
+SL R V DI KF V+ I+V AF G+ L YY ++
Sbjct: 625 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNE------------------ 666
Query: 629 CVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXX 688
+ + E+ +TLFWA FGL ++ S ++ F G +++G Y
Sbjct: 667 --AFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLI 724
Query: 689 XXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAW----RWL 744
S+Q I + ADVEWKFAR+KLW SYFEEG T P PFN++PSPKSL Y +W+
Sbjct: 725 AMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLKLKKWI 784
Query: 745 QRRLCGHARAKRE 757
GH + +E
Sbjct: 785 SELFQGHKKGFQE 797
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/57 (40%), Positives = 33/57 (57%)
Query: 751 HARAKREHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
H + R + IM+ L++RYV Q ES V E ++ EIKQD+S+ R EL+E
Sbjct: 844 HLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLE 900
>BC093658-1|AAH93658.1| 931|Homo sapiens transient receptor
potential cation channel, subfamily C, member 6 protein.
Length = 931
Score = 438 bits (1080), Expect = e-122
Identities = 262/733 (35%), Positives = 395/733 (53%), Gaps = 68/733 (9%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
LS+EE+++L E G++ R++L+ +NV+CVD +G++AL +A+
Sbjct: 95 LSIEEERFLDAAEYGNIPVVRKMLEECHS---LNVNCVDYMGQNALQLAVANEHLEITEL 151
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDHE---ERTRKPGEPNSWE-------ALPP 170
+R DALL AIS+ +V VEA+L H E R P+ E A
Sbjct: 152 LLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDE 211
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ D+TP+ILAAH YEI+ LL +GA++ PHD C C+DC + ++ DS HSR
Sbjct: 212 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSR 271
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SRINAY+ +DP++TA ELS EL L+ +E EFK +Y++L +QC++F
Sbjct: 272 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVG 331
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
LLD R + E++ +LN + + G R LSRLKLAIK KKFVAHPN QQ
Sbjct: 332 LLDLCRNTEEVEAILNGD------VETLQSGDHGRPNLSRLKLAIKYEVKKFVAHPNCQQ 385
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L SIWYE++ G R++ M ++ ++ + P +L Y AP S +G+ +R PF+KF+
Sbjct: 386 QLLSIWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWFAPCSKMGKIMRGPFMKFVA 445
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSG 466
H+AS+ +FL LL++ A+ R E P D + + + S S +E LI++WV G
Sbjct: 446 HAASFTIFLGLLVMNAADRFEGTKLLPNETSTD-NAKQLFRMKTSCFSWMEMLIISWVIG 504
Query: 467 LIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR----------- 515
+IW+E K++W G +EY+ ++WN++DF +++ A+ R ++ + +
Sbjct: 505 MIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTL 564
Query: 516 ----EMAMG---LQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQ 568
++ +G +N R KWD DP ++SEGL++ A + S ++ YI N GPLQ
Sbjct: 565 KDLTKVTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQ 624
Query: 569 VSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDA 628
+SL R V DI KF V+ I+V AF G+ L YY ++
Sbjct: 625 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNE------------------ 666
Query: 629 CVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXX 688
+ + E+ +TLFWA FGL ++ S ++ F G +++G Y
Sbjct: 667 --AFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLI 724
Query: 689 XXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAW----RWL 744
S+Q I + ADVEWKFAR+KLW SYFEEG T P PFN++PSPKSL Y +W+
Sbjct: 725 AMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLKLKKWI 784
Query: 745 QRRLCGHARAKRE 757
GH + +E
Sbjct: 785 SELFQGHKKGFQE 797
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/57 (40%), Positives = 33/57 (57%)
Query: 751 HARAKREHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
H + R + IM+ L++RYV Q ES V E ++ EIKQD+S+ R EL+E
Sbjct: 844 HLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLE 900
>AJ271066-1|CAC01684.1| 931|Homo sapiens transient receptor
potential channel 6 protein.
Length = 931
Score = 438 bits (1080), Expect = e-122
Identities = 262/733 (35%), Positives = 395/733 (53%), Gaps = 68/733 (9%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
LS+EE+++L E G++ R++L+ +NV+CVD +G++AL +A+
Sbjct: 95 LSIEEERFLDAAEYGNIPVVRKMLEECHS---LNVNCVDYMGQNALQLAVANEHLEITEL 151
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDHE---ERTRKPGEPNSWE-------ALPP 170
+R DALL AIS+ +V VEA+L H E R P+ E A
Sbjct: 152 LLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDE 211
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ D+TP+ILAAH YEI+ LL +GA++ PHD C C+DC + ++ DS HSR
Sbjct: 212 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSR 271
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SRINAY+ +DP++TA ELS EL L+ +E EFK +Y++L +QC++F
Sbjct: 272 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVG 331
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
LLD R + E++ +LN + + G R LSRLKLAIK KKFVAHPN QQ
Sbjct: 332 LLDLCRNTEEVEAILNGD------VETLQSGDHGRPNLSRLKLAIKYEVKKFVAHPNCQQ 385
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L SIWYE++ G R++ M ++ ++ + P +L Y AP S +G+ +R PF+KF+
Sbjct: 386 QLLSIWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWFAPCSKMGKIMRGPFMKFVA 445
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSG 466
H+AS+ +FL LL++ A+ R E P D + + + S S +E LI++WV G
Sbjct: 446 HAASFTIFLGLLVMNAADRFEGTKLLPNETSTD-NAKQLFRMKTSCFSWMEMLIISWVIG 504
Query: 467 LIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR----------- 515
+IW+E K++W G +EY+ ++WN++DF +++ A+ R ++ + +
Sbjct: 505 MIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTL 564
Query: 516 ----EMAMG---LQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQ 568
++ +G +N R KWD DP ++SEGL++ A + S ++ YI N GPLQ
Sbjct: 565 KDLTKVTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQ 624
Query: 569 VSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDA 628
+SL R V DI KF V+ I+V AF G+ L YY ++
Sbjct: 625 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNE------------------ 666
Query: 629 CVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXX 688
+ + E+ +TLFWA FGL ++ S ++ F G +++G Y
Sbjct: 667 --AFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLI 724
Query: 689 XXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAW----RWL 744
S+Q I + ADVEWKFAR+KLW SYFEEG T P PFN++PSPKSL Y +W+
Sbjct: 725 AMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLKLKKWI 784
Query: 745 QRRLCGHARAKRE 757
GH + +E
Sbjct: 785 SELFQGHKKGFQE 797
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/57 (40%), Positives = 33/57 (57%)
Query: 751 HARAKREHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
H + R + IM+ L++RYV Q ES V E ++ EIKQD+S+ R EL+E
Sbjct: 844 HLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLE 900
>AJ006276-1|CAA06943.1| 931|Homo sapiens transient receptor
potential protein protein.
Length = 931
Score = 438 bits (1080), Expect = e-122
Identities = 262/733 (35%), Positives = 395/733 (53%), Gaps = 68/733 (9%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
LS+EE+++L E G++ R++L+ +NV+CVD +G++AL +A+
Sbjct: 95 LSIEEERFLDAAEYGNIPVVRKMLEECHS---LNVNCVDYMGQNALQLAVANEHLEITEL 151
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDHE---ERTRKPGEPNSWE-------ALPP 170
+R DALL AIS+ +V VEA+L H E R P+ E A
Sbjct: 152 LLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDE 211
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ D+TP+ILAAH YEI+ LL +GA++ PHD C C+DC + ++ DS HSR
Sbjct: 212 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSR 271
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SRINAY+ +DP++TA ELS EL L+ +E EFK +Y++L +QC++F
Sbjct: 272 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVG 331
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
LLD R + E++ +LN + + G R LSRLKLAIK KKFVAHPN QQ
Sbjct: 332 LLDLCRNTEEVEAILNGD------VETLQSGDHGRPNLSRLKLAIKYEVKKFVAHPNCQQ 385
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L SIWYE++ G R++ M ++ ++ + P +L Y AP S +G+ +R PF+KF+
Sbjct: 386 QLLSIWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWFAPCSKMGKIMRGPFMKFVA 445
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSG 466
H+AS+ +FL LL++ A+ R E P D + + + S S +E LI++WV G
Sbjct: 446 HAASFTIFLGLLVMNAADRFEGTKLLPNETSTD-NAKQLFRMKTSCFSWMEMLIISWVIG 504
Query: 467 LIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR----------- 515
+IW+E K++W G +EY+ ++WN++DF +++ A+ R ++ + +
Sbjct: 505 MIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTL 564
Query: 516 ----EMAMG---LQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQ 568
++ +G +N R KWD DP ++SEGL++ A + S ++ YI N GPLQ
Sbjct: 565 KDLTKVTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQ 624
Query: 569 VSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDA 628
+SL R V DI KF V+ I+V AF G+ L YY ++
Sbjct: 625 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNE------------------ 666
Query: 629 CVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXX 688
+ + E+ +TLFWA FGL ++ S ++ F G +++G Y
Sbjct: 667 --AFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLI 724
Query: 689 XXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAW----RWL 744
S+Q I + ADVEWKFAR+KLW SYFEEG T P PFN++PSPKSL Y +W+
Sbjct: 725 AMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLKLKKWI 784
Query: 745 QRRLCGHARAKRE 757
GH + +E
Sbjct: 785 SELFQGHKKGFQE 797
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/57 (40%), Positives = 33/57 (57%)
Query: 751 HARAKREHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
H + R + IM+ L++RYV Q ES V E ++ EIKQD+S+ R EL+E
Sbjct: 844 HLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLE 900
>AF080394-1|AAC63289.2| 931|Homo sapiens transient receptor
potential protein 6 protein.
Length = 931
Score = 438 bits (1080), Expect = e-122
Identities = 262/733 (35%), Positives = 395/733 (53%), Gaps = 68/733 (9%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
LS+EE+++L E G++ R++L+ +NV+CVD +G++AL +A+
Sbjct: 95 LSIEEERFLDAAEYGNIPVVRKMLEECHS---LNVNCVDYMGQNALQLAVANEHLEITEL 151
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDHE---ERTRKPGEPNSWE-------ALPP 170
+R DALL AIS+ +V VEA+L H E R P+ E A
Sbjct: 152 LLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDE 211
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ D+TP+ILAAH YEI+ LL +GA++ PHD C C+DC + ++ DS HSR
Sbjct: 212 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSR 271
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SRINAY+ +DP++TA ELS EL L+ +E EFK +Y++L +QC++F
Sbjct: 272 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVG 331
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
LLD R + E++ +LN + + G R LSRLKLAIK KKFVAHPN QQ
Sbjct: 332 LLDLCRNTEEVEAILNGD------VETLQSGDHGRPNLSRLKLAIKYEVKKFVAHPNCQQ 385
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L SIWYE++ G R++ M ++ ++ + P +L Y AP S +G+ +R PF+KF+
Sbjct: 386 QLLSIWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWFAPCSKMGKIMRGPFMKFVA 445
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSRRGSMPSIVEWLILAWVSG 466
H+AS+ +FL LL++ A+ R E P D + + + S S +E LI++WV G
Sbjct: 446 HAASFTIFLGLLVMNAADRFEGTKLLPNETSTD-NAKQLFRMKTSCFSWMEMLIISWVIG 504
Query: 467 LIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR----------- 515
+IW+E K++W G +EY+ ++WN++DF +++ A+ R ++ + +
Sbjct: 505 MIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTL 564
Query: 516 ----EMAMG---LQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQ 568
++ +G +N R KWD DP ++SEGL++ A + S ++ YI N GPLQ
Sbjct: 565 KDLTKVTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQ 624
Query: 569 VSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDA 628
+SL R V DI KF V+ I+V AF G+ L YY ++
Sbjct: 625 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNE------------------ 666
Query: 629 CVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXX 688
+ + E+ +TLFWA FGL ++ S ++ F G +++G Y
Sbjct: 667 --AFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLI 724
Query: 689 XXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAW----RWL 744
S+Q I + ADVEWKFAR+KLW SYFEEG T P PFN++PSPKSL Y +W+
Sbjct: 725 AMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLKLKKWI 784
Query: 745 QRRLCGHARAKRE 757
GH + +E
Sbjct: 785 SELFQGHKKGFQE 797
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/57 (40%), Positives = 33/57 (57%)
Query: 751 HARAKREHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
H + R + IM+ L++RYV Q ES V E ++ EIKQD+S+ R EL+E
Sbjct: 844 HLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLE 900
>Y13758-1|CAA74083.1| 848|Homo sapiens transient receptor potential
related channel 3 protein protein.
Length = 848
Score = 436 bits (1073), Expect = e-121
Identities = 260/712 (36%), Positives = 392/712 (55%), Gaps = 64/712 (8%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +NV+CVD +G++AL +A+
Sbjct: 36 LTAEEERFLDAAEYGNIPVVRKMLEESKT---LNVNCVDYMGQNALQLAVGNEHLEVTEL 92
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 93 LLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDE 152
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YE++ +LL +GA++ PHD C C DC+ +R DS HSR
Sbjct: 153 DGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSR 212
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SRINAY+ +DP+LTA ELS EL +L+ +E EFK +Y++L +QC++F
Sbjct: 213 SRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVG 272
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
+LD R S E++ +LN + ++ + + LSR+KLAIK KKFVAHPN QQ
Sbjct: 273 VLDLCRDSEEVEAILNGDLESAEPLEVHR----HKASLSRVKLAIKYEVKKFVAHPNCQQ 328
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L +IWYE++ G R + + ++ ++ + P ++ Y AP S +G+ LR PF+KF+
Sbjct: 329 QLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVA 388
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGSMPSIVEWLILAWVS 465
H+AS+ +FL LL+ AS R E T P + D + + + R + + + E LI+ WV
Sbjct: 389 HAASFIIFLGLLVFNASDRFEGITTLPNITVTD--YPKQIFRVKTTQFTWTEMLIMVWVL 446
Query: 466 GLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR---------- 515
G++WSE K+LW G REY+ +WNV+DF S+++A R ++ Q +
Sbjct: 447 GMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQ 506
Query: 516 -----EMAMGLQ---WNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPL 567
E+ + + + R+KW DP ++SEGL++ A + S ++ YI N GPL
Sbjct: 507 ESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPL 566
Query: 568 QVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPD 627
Q+SL R V DI KF VL I+V FAF G+ L YY + V A T
Sbjct: 567 QISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAK-----VNAAFT--------- 612
Query: 628 ACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXX 687
+ E+ +TLFW+ FGL ++ S L F G +++G Y
Sbjct: 613 ------TVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNML 666
Query: 688 XXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLY 739
SYQ I + +DVEWKFARSKLW+SYF++G T PPPF+++PSPKS +Y
Sbjct: 667 IAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVY 718
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 778 IMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLE 820
>U47050-1|AAC51653.1| 848|Homo sapiens calcium influx channel
protein.
Length = 848
Score = 436 bits (1073), Expect = e-121
Identities = 260/712 (36%), Positives = 392/712 (55%), Gaps = 64/712 (8%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +NV+CVD +G++AL +A+
Sbjct: 36 LTAEEERFLDAAEYGNIPVVRKMLEESKT---LNVNCVDYMGQNALQLAVGNEHLEVTEL 92
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 93 LLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDE 152
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YE++ +LL +GA++ PHD C C DC+ +R DS HSR
Sbjct: 153 DGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSR 212
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SRINAY+ +DP+LTA ELS EL +L+ +E EFK +Y++L +QC++F
Sbjct: 213 SRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVG 272
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
+LD R S E++ +LN + ++ + + LSR+KLAIK KKFVAHPN QQ
Sbjct: 273 VLDLCRDSEEVEAILNGDLESAEPLEVHR----HKASLSRVKLAIKYEVKKFVAHPNCQQ 328
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L +IWYE++ G R + + ++ ++ + P ++ Y AP S +G+ LR PF+KF+
Sbjct: 329 QLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVA 388
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGSMPSIVEWLILAWVS 465
H+AS+ +FL LL+ AS R E T P + D + + + R + + + E LI+ WV
Sbjct: 389 HAASFIIFLGLLVFNASDRFEGITTLPNITVTD--YPKQIFRVKTTQFTWTEMLIMVWVL 446
Query: 466 GLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR---------- 515
G++WSE K+LW G REY+ +WNV+DF S+++A R ++ Q +
Sbjct: 447 GMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQ 506
Query: 516 -----EMAMGLQ---WNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPL 567
E+ + + + R+KW DP ++SEGL++ A + S ++ YI N GPL
Sbjct: 507 ESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPL 566
Query: 568 QVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPD 627
Q+SL R V DI KF VL I+V FAF G+ L YY + V A T
Sbjct: 567 QISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAK-----VNAAFT--------- 612
Query: 628 ACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXX 687
+ E+ +TLFW+ FGL ++ S L F G +++G Y
Sbjct: 613 ------TVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNML 666
Query: 688 XXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLY 739
SYQ I + +DVEWKFARSKLW+SYF++G T PPPF+++PSPKS +Y
Sbjct: 667 IAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVY 718
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 778 IMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLE 820
>BC093684-1|AAH93684.1| 848|Homo sapiens transient receptor
potential cation channel, subfamily C, member 3 protein.
Length = 848
Score = 436 bits (1073), Expect = e-121
Identities = 260/712 (36%), Positives = 392/712 (55%), Gaps = 64/712 (8%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +NV+CVD +G++AL +A+
Sbjct: 36 LTAEEERFLDAAEYGNIPVVRKMLEESKT---LNVNCVDYMGQNALQLAVGNEHLEVTEL 92
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 93 LLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDE 152
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YE++ +LL +GA++ PHD C C DC+ +R DS HSR
Sbjct: 153 DGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSR 212
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SRINAY+ +DP+LTA ELS EL +L+ +E EFK +Y++L +QC++F
Sbjct: 213 SRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVG 272
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
+LD R S E++ +LN + ++ + + LSR+KLAIK KKFVAHPN QQ
Sbjct: 273 VLDLCRDSEEVEAILNGDLESAEPLEVHR----HKASLSRVKLAIKYEVKKFVAHPNCQQ 328
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L +IWYE++ G R + + ++ ++ + P ++ Y AP S +G+ LR PF+KF+
Sbjct: 329 QLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVA 388
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGSMPSIVEWLILAWVS 465
H+AS+ +FL LL+ AS R E T P + D + + + R + + + E LI+ WV
Sbjct: 389 HAASFIIFLGLLVFNASDRFEGITTLPNITVTD--YPKQIFRVKTTQFTWTEMLIMVWVL 446
Query: 466 GLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR---------- 515
G++WSE K+LW G REY+ +WNV+DF S+++A R ++ Q +
Sbjct: 447 GMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQ 506
Query: 516 -----EMAMGLQ---WNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPL 567
E+ + + + R+KW DP ++SEGL++ A + S ++ YI N GPL
Sbjct: 507 ESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPL 566
Query: 568 QVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPD 627
Q+SL R V DI KF VL I+V FAF G+ L YY + V A T
Sbjct: 567 QISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAK-----VNAAFT--------- 612
Query: 628 ACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXX 687
+ E+ +TLFW+ FGL ++ S L F G +++G Y
Sbjct: 613 ------TVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNML 666
Query: 688 XXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLY 739
SYQ I + +DVEWKFARSKLW+SYF++G T PPPF+++PSPKS +Y
Sbjct: 667 IAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVY 718
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 778 IMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLE 820
>BC093682-1|AAH93682.1| 848|Homo sapiens transient receptor
potential cation channel, subfamily C, member 3 protein.
Length = 848
Score = 436 bits (1073), Expect = e-121
Identities = 260/712 (36%), Positives = 392/712 (55%), Gaps = 64/712 (8%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +NV+CVD +G++AL +A+
Sbjct: 36 LTAEEERFLDAAEYGNIPVVRKMLEESKT---LNVNCVDYMGQNALQLAVGNEHLEVTEL 92
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 93 LLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDE 152
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YE++ +LL +GA++ PHD C C DC+ +R DS HSR
Sbjct: 153 DGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSR 212
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SRINAY+ +DP+LTA ELS EL +L+ +E EFK +Y++L +QC++F
Sbjct: 213 SRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVG 272
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
+LD R S E++ +LN + ++ + + LSR+KLAIK KKFVAHPN QQ
Sbjct: 273 VLDLCRDSEEVEAILNGDLESAEPLEVHR----HKASLSRVKLAIKYEVKKFVAHPNCQQ 328
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L +IWYE++ G R + + ++ ++ + P ++ Y AP S +G+ LR PF+KF+
Sbjct: 329 QLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVA 388
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGSMPSIVEWLILAWVS 465
H+AS+ +FL LL+ AS R E T P + D + + + R + + + E LI+ WV
Sbjct: 389 HAASFIIFLGLLVFNASDRFEGITTLPNITVTD--YPKQIFRVKTTQFTWTEMLIMVWVL 446
Query: 466 GLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR---------- 515
G++WSE K+LW G REY+ +WNV+DF S+++A R ++ Q +
Sbjct: 447 GMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQ 506
Query: 516 -----EMAMGLQ---WNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPL 567
E+ + + + R+KW DP ++SEGL++ A + S ++ YI N GPL
Sbjct: 507 ESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPL 566
Query: 568 QVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPD 627
Q+SL R V DI KF VL I+V FAF G+ L YY + V A T
Sbjct: 567 QISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAK-----VNAAFT--------- 612
Query: 628 ACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXX 687
+ E+ +TLFW+ FGL ++ S L F G +++G Y
Sbjct: 613 ------TVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNML 666
Query: 688 XXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLY 739
SYQ I + +DVEWKFARSKLW+SYF++G T PPPF+++PSPKS +Y
Sbjct: 667 IAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVY 718
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 778 IMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLE 820
>AY865574-1|AAW62292.1| 921|Homo sapiens N-terminally extended type
3 canonical transient receptor potential channel
protein.
Length = 921
Score = 436 bits (1073), Expect = e-121
Identities = 260/712 (36%), Positives = 392/712 (55%), Gaps = 64/712 (8%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +NV+CVD +G++AL +A+
Sbjct: 109 LTAEEERFLDAAEYGNIPVVRKMLEESKT---LNVNCVDYMGQNALQLAVGNEHLEVTEL 165
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 166 LLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDE 225
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YE++ +LL +GA++ PHD C C DC+ +R DS HSR
Sbjct: 226 DGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSR 285
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SRINAY+ +DP+LTA ELS EL +L+ +E EFK +Y++L +QC++F
Sbjct: 286 SRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVG 345
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
+LD R S E++ +LN + ++ + + LSR+KLAIK KKFVAHPN QQ
Sbjct: 346 VLDLCRDSEEVEAILNGDLESAEPLEVHR----HKASLSRVKLAIKYEVKKFVAHPNCQQ 401
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L +IWYE++ G R + + ++ ++ + P ++ Y AP S +G+ LR PF+KF+
Sbjct: 402 QLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVA 461
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGSMPSIVEWLILAWVS 465
H+AS+ +FL LL+ AS R E T P + D + + + R + + + E LI+ WV
Sbjct: 462 HAASFIIFLGLLVFNASDRFEGITTLPNITVTD--YPKQIFRVKTTQFTWTEMLIMVWVL 519
Query: 466 GLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRR---------- 515
G++WSE K+LW G REY+ +WNV+DF S+++A R ++ Q +
Sbjct: 520 GMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQ 579
Query: 516 -----EMAMGLQ---WNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPL 567
E+ + + + R+KW DP ++SEGL++ A + S ++ YI N GPL
Sbjct: 580 ESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPL 639
Query: 568 QVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPD 627
Q+SL R V DI KF VL I+V FAF G+ L YY + V A T
Sbjct: 640 QISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAK-----VNAAFT--------- 685
Query: 628 ACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXX 687
+ E+ +TLFW+ FGL ++ S L F G +++G Y
Sbjct: 686 ------TVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNML 739
Query: 688 XXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLY 739
SYQ I + +DVEWKFARSKLW+SYF++G T PPPF+++PSPKS +Y
Sbjct: 740 IAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVY 791
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 851 IMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLE 893
>BC128185-1|AAI28186.1| 862|Homo sapiens transient receptor
potential cation channel, subfamily C, member 7 protein.
Length = 862
Score = 432 bits (1064), Expect = e-120
Identities = 263/712 (36%), Positives = 389/712 (54%), Gaps = 66/712 (9%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +N +CVD +G++AL +A+
Sbjct: 40 LTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVTEL 96
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 97 LLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDE 156
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YEI+ +LL +GA++ PHD C C++C +R+DS HSR
Sbjct: 157 DGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSR 216
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SR+NAY+ +DP+LTA ELS EL RL+ +E EFK +Y++L +QC++F
Sbjct: 217 SRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVG 276
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
+LD R + E++ +LN + + P LSR+KLAIK KKFVAHPN QQ
Sbjct: 277 VLDLCRDTEEVEAILNGDVNFQVWSDHHRPS------LSRIKLAIKYEVKKFVAHPNCQQ 330
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L ++WYE++ G R++++ ++ + + P ++AY AP S +GRTLR PF+KF+
Sbjct: 331 QLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVA 390
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGSMPSIVEWLILAWVS 465
H+ S+ +FL LL++ AS R E T P D + + + R + + S E LI+ WV
Sbjct: 391 HAVSFTIFLGLLVVNASDRFEGVKTLPNETFTD--YPKQIFRVKTTQFSWTEMLIMKWVL 448
Query: 466 GLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVS-------------HYQ 512
G+IWSE K++W+ G REYV +WN++DF S++VA+ R ++ H Q
Sbjct: 449 GMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQ 508
Query: 513 VRREMAMGL-----QWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPL 567
+ L + R+KW DP ++SEGL++ A + S ++ YI N GPL
Sbjct: 509 DDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPL 568
Query: 568 QVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPD 627
Q+SL R V DI KF V+ I+V AF G+ L YY G P T +
Sbjct: 569 QISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYR---------GAKYNPAFTTVE-- 617
Query: 628 ACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXX 687
E+ +TLFW+ FGL ++ S L F G +++G Y
Sbjct: 618 ---------ESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNML 668
Query: 688 XXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLY 739
+SYQ I E ADVEWKFAR+KLW+SYF+EG T P PFN++PSPKS Y
Sbjct: 669 IAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYY 720
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 783 IMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLE 825
>AJ272034-1|CAC03489.1| 862|Homo sapiens putative capacitative
calcium channel protein.
Length = 862
Score = 432 bits (1064), Expect = e-120
Identities = 263/712 (36%), Positives = 389/712 (54%), Gaps = 66/712 (9%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +N +CVD +G++AL +A+
Sbjct: 40 LTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVTEL 96
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 97 LLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDE 156
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YEI+ +LL +GA++ PHD C C++C +R+DS HSR
Sbjct: 157 DGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSR 216
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SR+NAY+ +DP+LTA ELS EL RL+ +E EFK +Y++L +QC++F
Sbjct: 217 SRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVG 276
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
+LD R + E++ +LN + + P LSR+KLAIK KKFVAHPN QQ
Sbjct: 277 VLDLCRDTEEVEAILNGDVNFQVWSDHHRPS------LSRIKLAIKYEVKKFVAHPNCQQ 330
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L ++WYE++ G R++++ ++ + + P ++AY AP S +GRTLR PF+KF+
Sbjct: 331 QLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVA 390
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGSMPSIVEWLILAWVS 465
H+ S+ +FL LL++ AS R E T P D + + + R + + S E LI+ WV
Sbjct: 391 HAVSFTIFLGLLVVNASDRFEGVKTLPNETFTD--YPKQIFRVKTTQFSWTEMLIMKWVL 448
Query: 466 GLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVS-------------HYQ 512
G+IWSE K++W+ G REYV +WN++DF S++VA+ R ++ H Q
Sbjct: 449 GMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQ 508
Query: 513 VRREMAMGL-----QWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPL 567
+ L + R+KW DP ++SEGL++ A + S ++ YI N GPL
Sbjct: 509 DDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPL 568
Query: 568 QVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPD 627
Q+SL R V DI KF V+ I+V AF G+ L YY G P T +
Sbjct: 569 QISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYR---------GAKYNPAFTTVE-- 617
Query: 628 ACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXX 687
E+ +TLFW+ FGL ++ S L F G +++G Y
Sbjct: 618 ---------ESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNML 668
Query: 688 XXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLY 739
+SYQ I E ADVEWKFAR+KLW+SYF+EG T P PFN++PSPKS Y
Sbjct: 669 IAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYY 720
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 783 IMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLE 825
>AJ421783-1|CAD19069.1| 862|Homo sapiens short transient receptor
potential channel 7 protein.
Length = 862
Score = 429 bits (1057), Expect = e-119
Identities = 262/712 (36%), Positives = 388/712 (54%), Gaps = 66/712 (9%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +N +CVD +G++AL +A+
Sbjct: 40 LTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVTEL 96
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DAL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 97 LLKKENLARVGDALPLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDE 156
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YEI+ +LL +GA++ PHD C C++C +R+DS HSR
Sbjct: 157 DGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSR 216
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SR+NAY+ +DP+LTA ELS EL RL+ +E EFK +Y++L +QC++F
Sbjct: 217 SRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVG 276
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
+LD R + E++ +LN + + P LSR+KLAIK KKFVAHPN QQ
Sbjct: 277 VLDLCRDTEEVEAILNGDVNFQVWSDHHRPS------LSRIKLAIKYEVKKFVAHPNCQQ 330
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRTLRKPFIKFLC 410
L ++WYE++ G R++++ ++ + + P ++AY AP S +GRTLR PF+KF+
Sbjct: 331 QLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVA 390
Query: 411 HSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGSMPSIVEWLILAWVS 465
H+ S+ +FL LL++ AS R E T P D + + + R + + S E LI+ WV
Sbjct: 391 HAVSFTIFLGLLVVNASDRFEGVKTLPNETFTD--YPKQIFRVKTTQFSWTEMLIMKWVL 448
Query: 466 GLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVS-------------HYQ 512
G+IWSE K++W+ G REYV +WN++DF S++VA+ R ++ H Q
Sbjct: 449 GMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQ 508
Query: 513 VRREMAMGL-----QWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPL 567
+ L + R+KW DP ++SEGL++ A + S ++ YI N GPL
Sbjct: 509 DDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPL 568
Query: 568 QVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPD 627
Q+SL R V DI KF V+ I+V AF G+ L YY G P T +
Sbjct: 569 QISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYR---------GAKYNPAFTTVE-- 617
Query: 628 ACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXX 687
E+ +TLFW+ FGL ++ S L F G +++G Y
Sbjct: 618 ---------ESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNML 668
Query: 688 XXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLY 739
+SYQ I E ADVEWKFAR+KLW+SYF+EG T P PFN++PSPKS Y
Sbjct: 669 IAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYY 720
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 783 IMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLE 825
>AJ549088-1|CAD70161.1| 801|Homo sapiens transient receptor
potential channel 7 protein.
Length = 801
Score = 260 bits (637), Expect = 2e-68
Identities = 158/422 (37%), Positives = 227/422 (53%), Gaps = 45/422 (10%)
Query: 341 KFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAVGRT 400
KFVAHPN QQ L ++WYE++ G R++++ ++ + + P ++AY AP S +GRT
Sbjct: 260 KFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRT 319
Query: 401 LRKPFIKFLCHSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGSMPSI 455
LR PF+KF+ H+ S+ +FL LL++ AS R E T P D + + + R + + S
Sbjct: 320 LRSPFMKFVAHAVSFTIFLGLLVVNASDRFESVKTLPNETFTD--YPKQIFRVKTTQFSW 377
Query: 456 VEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVS------ 509
E LI+ WV G+IWSE K++W+ G REYV +WN++DF S++VA+ R ++
Sbjct: 378 TEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASSTARFMAFLKATE 437
Query: 510 -------HYQVRREMAMGL-----QWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYI 557
H Q + L + R+KW DP ++SEGL++ A + S ++ YI
Sbjct: 438 AQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYI 497
Query: 558 FSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTAL 617
N GPLQ+SL R V DI KF V+ I+V AF G+ L YY G
Sbjct: 498 LPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYR---------GAKY 548
Query: 618 TPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXX 677
P T + E+ +TLFW+ FGL ++ S L F G +++G Y
Sbjct: 549 NPAFTTVE-----------ESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNV 597
Query: 678 XXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSL 737
+SYQ I E ADVEWKFAR+KLW+SYF+EG T P PFN++PSPKS
Sbjct: 598 TMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSF 657
Query: 738 LY 739
Y
Sbjct: 658 YY 659
Score = 142 bits (345), Expect = 4e-33
Identities = 84/224 (37%), Positives = 127/224 (56%), Gaps = 15/224 (6%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +N +CVD +G++AL +A+
Sbjct: 40 LTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVTEL 96
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 97 LLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDE 156
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YEI+ +LL +GA++ PHD C C++C +R+DS HSR
Sbjct: 157 DGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSR 216
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFK 274
SR+NAY+ +DP+LTA ELS EL RL+ +E EFK
Sbjct: 217 SRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFK 260
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 722 IMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLE 764
>AF421361-1|AAL24552.1| 323|Homo sapiens transient receptor
potential channel 4 eta splice variant protein.
Length = 323
Score = 252 bits (617), Expect = 5e-66
Identities = 138/289 (47%), Positives = 183/289 (63%), Gaps = 11/289 (3%)
Query: 53 VVRPHQEMAVLSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAI 112
+VR E LS EK YL VE+GD A ++ L+ A IN++C+DPLGR+ALL+AI
Sbjct: 22 IVRAESE---LSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAI 78
Query: 113 DXXXXXXXXXXXXFGVETRDALLHAISEEFVEAVEALLDHEERTRKPGEPNSWEALPPET 172
+ F V DALLHAI +E V AVE LL+H++ + + P L +
Sbjct: 79 ENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPI--LLDKQF 136
Query: 173 ATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSRSR 232
+ FT DITP+ILAAH ++YEIIKLL+ +G +P PH+VRC C +CV S DSLRHSRSR
Sbjct: 137 SEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSR 196
Query: 233 INAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATALL 292
+N Y+ +DP LTAF+LSWEL+ LS +E+EFK+EY+EL QC++FA LL
Sbjct: 197 LNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLL 256
Query: 293 DHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKK 341
D TR+S EL+I+LN+ S L E + L+RLKLAIK RQK+
Sbjct: 257 DQTRSSRELEIILNYRDDNS----LIEEQSGN--DLARLKLAIKYRQKE 299
>BC128186-1|AAI28187.1| 380|Homo sapiens TRPC7 protein protein.
Length = 380
Score = 222 bits (542), Expect = 6e-57
Identities = 127/347 (36%), Positives = 198/347 (57%), Gaps = 21/347 (6%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +N +CVD +G++AL +A+
Sbjct: 40 LTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVTEL 96
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 97 LLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDE 156
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YEI+ +LL +GA++ PHD C C++C +R+DS HSR
Sbjct: 157 DGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSR 216
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SR+NAY+ +DP+LTA ELS EL RL+ +E EFK +Y++L +QC++F
Sbjct: 217 SRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVG 276
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKKFVAHPNVQQ 350
+LD R + E++ +LN + + P LSR+KLAIK KKFVAHPN QQ
Sbjct: 277 VLDLCRDTEEVEAILNGDVNFQVWSDHHRPS------LSRIKLAIKYEVKKFVAHPNCQQ 330
Query: 351 LLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYIAAPHSAV 397
L ++WYE++ G R++++ ++ + + P ++AY AP S V
Sbjct: 331 QLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKV 377
>AY167927-1|AAO12125.1| 746|Homo sapiens transient receptor
potential channel 7 gamma splice variant protein.
Length = 746
Score = 215 bits (526), Expect = 5e-55
Identities = 137/366 (37%), Positives = 192/366 (52%), Gaps = 45/366 (12%)
Query: 397 VGRTLRKPFIKFLCHSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGS 451
+GRTLR PF+KF+ H+ S+ +FL LL++ AS R E T P D + + + R + +
Sbjct: 261 LGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTD--YPKQIFRVKTT 318
Query: 452 MPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVS-- 509
S E LI+ WV G+IWSE K++W+ G REYV +WN++DF S++VA+ R ++
Sbjct: 319 QFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFL 378
Query: 510 -----------HYQVRREMAMGLQ-----WNQPREKWDAWDPMLLSEGLFSAANIFSSLK 553
H Q + L + R+KW DP ++SEGL++ A + S +
Sbjct: 379 KATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSR 438
Query: 554 LVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTV 613
+ YI N GPLQ+SL R V DI KF V+ I+V AF G+ L YY
Sbjct: 439 IAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYR--------- 489
Query: 614 GTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFG 673
G P T + E+ +TLFW+ FGL ++ S L F G +++G
Sbjct: 490 GAKYNPAFTTVE-----------ESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYG 538
Query: 674 TYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPS 733
Y +SYQ I E ADVEWKFAR+KLW+SYF+EG T P PFN++PS
Sbjct: 539 VYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPS 598
Query: 734 PKSLLY 739
PKS Y
Sbjct: 599 PKSFYY 604
Score = 142 bits (345), Expect = 4e-33
Identities = 84/224 (37%), Positives = 127/224 (56%), Gaps = 15/224 (6%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +N +CVD +G++AL +A+
Sbjct: 40 LTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVTEL 96
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 97 LLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDE 156
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YEI+ +LL +GA++ PHD C C++C +R+DS HSR
Sbjct: 157 DGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSR 216
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFK 274
SR+NAY+ +DP+LTA ELS EL RL+ +E EFK
Sbjct: 217 SRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFK 260
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 667 IMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLE 709
>AY167926-1|AAO12124.1| 806|Homo sapiens transient receptor
potential channel 7 beta splice variant protein.
Length = 806
Score = 215 bits (526), Expect = 5e-55
Identities = 137/366 (37%), Positives = 192/366 (52%), Gaps = 45/366 (12%)
Query: 397 VGRTLRKPFIKFLCHSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGS 451
+GRTLR PF+KF+ H+ S+ +FL LL++ AS R E T P D + + + R + +
Sbjct: 321 LGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTD--YPKQIFRVKTT 378
Query: 452 MPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVS-- 509
S E LI+ WV G+IWSE K++W+ G REYV +WN++DF S++VA+ R ++
Sbjct: 379 QFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFL 438
Query: 510 -----------HYQVRREMAMGLQ-----WNQPREKWDAWDPMLLSEGLFSAANIFSSLK 553
H Q + L + R+KW DP ++SEGL++ A + S +
Sbjct: 439 KATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSR 498
Query: 554 LVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTV 613
+ YI N GPLQ+SL R V DI KF V+ I+V AF G+ L YY
Sbjct: 499 IAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYR--------- 549
Query: 614 GTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFG 673
G P T + E+ +TLFW+ FGL ++ S L F G +++G
Sbjct: 550 GAKYNPAFTTVE-----------ESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYG 598
Query: 674 TYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPS 733
Y +SYQ I E ADVEWKFAR+KLW+SYF+EG T P PFN++PS
Sbjct: 599 VYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPS 658
Query: 734 PKSLLY 739
PKS Y
Sbjct: 659 PKSFYY 664
Score = 175 bits (426), Expect = 7e-43
Identities = 105/290 (36%), Positives = 162/290 (55%), Gaps = 21/290 (7%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +N +CVD +G++AL +A+
Sbjct: 40 LTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVTEL 96
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 97 LLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDE 156
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YEI+ +LL +GA++ PHD C C++C +R+DS HSR
Sbjct: 157 DGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSR 216
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SR+NAY+ +DP+LTA ELS EL RL+ +E EFK +Y++L +QC++F
Sbjct: 217 SRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVG 276
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQK 340
+LD R + E++ +LN + + P LSR+KLAIK K
Sbjct: 277 VLDLCRDTEEVEAILNGDVNFQVWSDHHRPS------LSRIKLAIKYEVK 320
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 727 IMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLE 769
>AJ549089-1|CAD70162.1| 807|Homo sapiens transient receptor
potential channel 7 protein.
Length = 807
Score = 215 bits (526), Expect = 5e-55
Identities = 137/366 (37%), Positives = 192/366 (52%), Gaps = 45/366 (12%)
Query: 397 VGRTLRKPFIKFLCHSASYFMFLFLLIL-ASQRIE---TAPGGLLWDVSHDEPLSR-RGS 451
+GRTLR PF+KF+ H+ S+ +FL LL++ AS R E T P D + + + R + +
Sbjct: 322 LGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTD--YPKQIFRVKTT 379
Query: 452 MPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVS-- 509
S E LI+ WV G+IWSE K++W+ G REYV +WN++DF S++VA+ R ++
Sbjct: 380 QFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFL 439
Query: 510 -----------HYQVRREMAMGLQ-----WNQPREKWDAWDPMLLSEGLFSAANIFSSLK 553
H Q + L + R+KW DP ++SEGL++ A + S +
Sbjct: 440 KATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSR 499
Query: 554 LVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTV 613
+ YI N GPLQ+SL R V DI KF V+ I+V AF G+ L YY
Sbjct: 500 IAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYR--------- 550
Query: 614 GTALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFG 673
G P T + E+ +TLFW+ FGL ++ S L F G +++G
Sbjct: 551 GAKYNPAFTTVE-----------ESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYG 599
Query: 674 TYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPS 733
Y +SYQ I E ADVEWKFAR+KLW+SYF+EG T P PFN++PS
Sbjct: 600 VYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPS 659
Query: 734 PKSLLY 739
PKS Y
Sbjct: 660 PKSFYY 665
Score = 177 bits (431), Expect = 2e-43
Identities = 106/291 (36%), Positives = 163/291 (56%), Gaps = 21/291 (7%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +N +CVD +G++AL +A+
Sbjct: 40 LTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVTEL 96
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 97 LLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDE 156
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YEI+ +LL +GA++ PHD C C++C +R+DS HSR
Sbjct: 157 DGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSR 216
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SR+NAY+ +DP+LTA ELS EL RL+ +E EFK +Y++L +QC++F
Sbjct: 217 SRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVG 276
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKK 341
+LD R + E++ +LN + + P LSR+KLAIK KK
Sbjct: 277 VLDLCRDTEEVEAILNGDVNFQVWSDHHRPS------LSRIKLAIKYEVKK 321
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 728 IMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLE 770
>AJ271067-1|CAC01685.1| 815|Homo sapiens transient receptor
potential channel 6, variant delta316-431 protein.
Length = 815
Score = 214 bits (523), Expect = 1e-54
Identities = 129/387 (33%), Positives = 201/387 (51%), Gaps = 47/387 (12%)
Query: 397 VGRTLRKPFIKFLCHSASYFMFLFLLIL-ASQRIETA---PGGLLWDVSHDEPLSRRGSM 452
+G+ +R PF+KF+ H+AS+ +FL LL++ A+ R E P D + + + S
Sbjct: 316 MGKIMRGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKLLPNETSTD-NAKQLFRMKTSC 374
Query: 453 PSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQ 512
S +E LI++WV G+IW+E K++W G +EY+ ++WN++DF +++ A+ R ++ +
Sbjct: 375 FSWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWH 434
Query: 513 VRR---------------EMAMG---LQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKL 554
+ ++ +G +N R KWD DP ++SEGL++ A + S ++
Sbjct: 435 ASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRI 494
Query: 555 VYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVG 614
YI N GPLQ+SL R V DI KF V+ I+V AF G+ L YY ++
Sbjct: 495 AYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEA--- 551
Query: 615 TALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGT 674
+ + E+ +TLFWA FGL ++ S ++ F G +++G
Sbjct: 552 -----------------FTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGV 594
Query: 675 YXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSP 734
Y S+Q I + ADVEWKFAR+KLW SYFEEG T P PFN++PSP
Sbjct: 595 YNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSP 654
Query: 735 KSLLYAW----RWLQRRLCGHARAKRE 757
KSL Y +W+ GH + +E
Sbjct: 655 KSLFYLLLKLKKWISELFQGHKKGFQE 681
Score = 142 bits (344), Expect = 6e-33
Identities = 85/224 (37%), Positives = 124/224 (55%), Gaps = 15/224 (6%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
LS+EE+++L E G++ R++L+ +NV+CVD +G++AL +A+
Sbjct: 95 LSIEEERFLDAAEYGNIPVVRKMLEECHS---LNVNCVDYMGQNALQLAVANEHLEITEL 151
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDHE---ERTRKPGEPNSWE-------ALPP 170
+R DALL AIS+ +V VEA+L H E R P+ E A
Sbjct: 152 LLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDE 211
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ D+TP+ILAAH YEI+ LL +GA++ PHD C C+DC + ++ DS HSR
Sbjct: 212 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSR 271
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFK 274
SRINAY+ +DP++TA ELS EL L+ +E EFK
Sbjct: 272 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFK 315
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/57 (40%), Positives = 33/57 (57%)
Query: 751 HARAKREHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
H + R + IM+ L++RYV Q ES V E ++ EIKQD+S+ R EL+E
Sbjct: 728 HLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLE 784
>AJ271068-1|CAC01686.1| 876|Homo sapiens transient receptor
potential channel 6, variant delta377-431 protein.
Length = 876
Score = 212 bits (518), Expect = 5e-54
Identities = 128/387 (33%), Positives = 200/387 (51%), Gaps = 47/387 (12%)
Query: 397 VGRTLRKPFIKFLCHSASYFMFLFLLIL-ASQRIETA---PGGLLWDVSHDEPLSRRGSM 452
+G+ +R PF+KF+ H+AS+ +FL LL++ A+ R E P D + + + S
Sbjct: 377 MGKIMRGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKLLPNETSTD-NAKQLFRMKTSC 435
Query: 453 PSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQ 512
S +E LI++WV G+IW+E K++W G +EY+ ++WN++DF +++ A+ R ++ +
Sbjct: 436 FSWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWH 495
Query: 513 VRR---------------EMAMG---LQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKL 554
+ ++ +G +N R KWD DP ++SEGL++ A + S ++
Sbjct: 496 ASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRI 555
Query: 555 VYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVG 614
Y N GPLQ+SL R V DI KF V+ I+V AF G+ L YY ++
Sbjct: 556 AYTLPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEA--- 612
Query: 615 TALTPNGTLPDPDACVVWRRLFETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGT 674
+ + E+ +TLFWA FGL ++ S ++ F G +++G
Sbjct: 613 -----------------FTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGV 655
Query: 675 YXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSP 734
Y S+Q I + ADVEWKFAR+KLW SYFEEG T P PFN++PSP
Sbjct: 656 YNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSP 715
Query: 735 KSLLYAW----RWLQRRLCGHARAKRE 757
KSL Y +W+ GH + +E
Sbjct: 716 KSLFYLLLKLKKWISELFQGHKKGFQE 742
Score = 182 bits (443), Expect = 6e-45
Identities = 110/291 (37%), Positives = 161/291 (55%), Gaps = 21/291 (7%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
LS+EE+++L E G++ R++L+ +NV+CVD +G++AL +A+
Sbjct: 95 LSIEEERFLDAAEYGNIPVVRKMLEECHS---LNVNCVDYMGQNALQLAVANEHLEITEL 151
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDHE---ERTRKPGEPNSWE-------ALPP 170
+R DALL AIS+ +V VEA+L H E R P+ E A
Sbjct: 152 LLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDE 211
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ D+TP+ILAAH YEI+ LL +GA++ PHD C C+DC + ++ DS HSR
Sbjct: 212 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSR 271
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFKTEYQELRVQCQEFATA 290
SRINAY+ +DP++TA ELS EL L+ +E EFK +Y++L +QC++F
Sbjct: 272 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVG 331
Query: 291 LLDHTRTSNELQILLNHEKGASPQAPLTEPGAPERMRLSRLKLAIKLRQKK 341
LLD R + E++ +LN + + G R LSRLKLAIK KK
Sbjct: 332 LLDLRRNTEEVEAILNGD------VETLQSGDHGRPNLSRLKLAIKYEVKK 376
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/57 (40%), Positives = 33/57 (57%)
Query: 751 HARAKREHMRTIRAIMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
H + R + IM+ L++RYV Q ES V E ++ EIKQD+S+ R EL+E
Sbjct: 789 HLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLE 845
>AJ549090-1|CAD70163.1| 261|Homo sapiens transient receptor
potential channel 7 protein.
Length = 261
Score = 142 bits (345), Expect = 4e-33
Identities = 84/224 (37%), Positives = 127/224 (56%), Gaps = 15/224 (6%)
Query: 63 LSLEEKKYLLGVERGDVAGTRRVLQRARDTGHINVDCVDPLGRSALLMAIDXXXXXXXXX 122
L+ EE+++L E G++ R++L+ ++ +N +CVD +G++AL +A+
Sbjct: 40 LTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVTEL 96
Query: 123 XXXFGVETR--DALLHAISEEFVEAVEALLDH------EERTRKPGEP----NSWEALPP 170
R DALL AIS+ +V VEA+L+H + T P E + + A
Sbjct: 97 LLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDE 156
Query: 171 ETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDSLRHSR 230
+ F+ DITP+ILAAH YEI+ +LL +GA++ PHD C C++C +R+DS HSR
Sbjct: 157 DGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSR 216
Query: 231 SRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEHEFK 274
SR+NAY+ +DP+LTA ELS EL RL+ +E EFK
Sbjct: 217 SRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFK 260
>AJ007018-1|CAC06090.1| 157|Homo sapiens putative capacitative
calcium entry channel protein.
Length = 157
Score = 102 bits (245), Expect = 6e-21
Identities = 51/152 (33%), Positives = 87/152 (57%), Gaps = 18/152 (11%)
Query: 454 SIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513
S +E LI++WV G+IW+E K++W G +EY+ ++WN++DF +++ A+ R ++ +
Sbjct: 6 SWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHA 65
Query: 514 RR---------------EMAMG---LQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLV 555
+ ++ +G +N R +WD DP ++SEGL++ A + S ++
Sbjct: 66 SKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIRWDPSDPQIISEGLYAIAVVLSFSRIA 125
Query: 556 YIFSVNPHLGPLQVSLSRMVLDILKFFVLDIL 587
YI N GPLQ+SL R V DI KF V+ I+
Sbjct: 126 YILPANESFGPLQISLGRTVKDIFKFMVIFIM 157
>AB231779-1|BAE46900.1| 149|Homo sapiens hypothetical protein
protein.
Length = 149
Score = 85.4 bits (202), Expect = 9e-16
Identities = 57/151 (37%), Positives = 76/151 (50%), Gaps = 10/151 (6%)
Query: 212 CGCDDCVRSRREDSLRHSRSRINAYRXXXXXXXXXXXXKDPILTAFELSWELRRLSALEH 271
C C +C +RR D L+ S SRIN Y +D +L AF+LS ELRRL+ E
Sbjct: 2 CACLECSNARRYDLLKLSLSRINTYLGIASRAHLSLASEDAMLAAFQLSRELRRLARKEP 61
Query: 272 EFKTEYQELRVQCQEFATALLDHTRTSNELQILLN---HEKGASPQAP----LTEPGAPE 324
EFK EY L Q++ LL +E+ +LN + P+A E G P
Sbjct: 62 EFKPEYIALESLSQDYGFQLLGMCWNQSEVTAVLNDLAEDSETEPEAEGLGLAFEEGIPS 121
Query: 325 RMRLSRLKLAIKLRQKKFVAHPNVQQLLASI 355
L R +LA+ QK+FVAH QQ+L+SI
Sbjct: 122 ---LVRPRLAVNYNQKRFVAHLICQQVLSSI 149
>X89068-1|CAA61448.1| 117|Homo sapiens TRPC3 protein protein.
Length = 117
Score = 81.0 bits (191), Expect = 2e-14
Identities = 34/72 (47%), Positives = 46/72 (63%)
Query: 668 GMLMFGTYXXXXXXXXXXXXXXXXXHSYQLISERADVEWKFARSKLWISYFEEGGTAPPP 727
G +++G Y SYQ I + +DVEWKFARSKLW+SYF++G T PPP
Sbjct: 16 GYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPP 75
Query: 728 FNVLPSPKSLLY 739
F+++PSPKS +Y
Sbjct: 76 FSLVPSPKSFVY 87
>U40983-1|AAC50630.1| 120|Homo sapiens trp-related protein 4
protein.
Length = 120
Score = 78.2 bits (184), Expect = 1e-13
Identities = 47/129 (36%), Positives = 64/129 (49%), Gaps = 9/129 (6%)
Query: 576 LDILKFFVLDILVIFAFSCGLNQLLWYYADMEKKRCTVGTALTPNGTLPDPDACVVWRRL 635
LDILKF + LV+ AF+ GLNQL +YY + + C N + L
Sbjct: 1 LDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNA---------FSTL 51
Query: 636 FETMQTLFWAAFGLVDLDSFELDGIKIFTRFWGMLMFGTYXXXXXXXXXXXXXXXXXHSY 695
FET+Q+LFW+ FGL++L + FT F G MFGTY +SY
Sbjct: 52 FETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSY 111
Query: 696 QLISERADV 704
QLI++ AD+
Sbjct: 112 QLIADHADI 120
>EF522961-1|ABP94017.1| 129|Homo sapiens TRPC1 splice variant
protein.
Length = 129
Score = 58.0 bits (134), Expect = 2e-07
Identities = 43/138 (31%), Positives = 69/138 (50%), Gaps = 11/138 (7%)
Query: 476 WDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDP 535
W GL +++ + N + FV NSLY+AT AL++V+H + + A W W
Sbjct: 1 WYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKF-HDFADRKDW-----LWYEGLE 54
Query: 536 MLLSEGLFSAANIFSSLKL-VYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSC 594
L E + + +SL L + V H ++S+ +M+ D KF + +LV+F+F+
Sbjct: 55 DFLEESRNQLSFVMNSLYLATFALKVVAH---NKISMGQMLQDFGKFLGMFLLVLFSFTI 111
Query: 595 GLNQLL-WYYADMEKKRC 611
GL QL Y E+K C
Sbjct: 112 GLTQLYDKGYTSKEQKDC 129
Score = 43.2 bits (97), Expect = 0.005
Identities = 17/39 (43%), Positives = 28/39 (71%)
Query: 475 LWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513
LW GL +++ + N + FV NSLY+AT AL++V+H ++
Sbjct: 48 LWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKI 86
>DQ012935-1|AAY22174.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2 protein.
Length = 1503
Score = 51.6 bits (118), Expect = 1e-05
Identities = 69/280 (24%), Positives = 117/280 (41%), Gaps = 61/280 (21%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVP---GFRRKNMLLQAAEMVRIGAM-FPLYS 386
L+LA++ + KFV+H +Q L +W+ + G R + + A ++ G + F
Sbjct: 718 LQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKR 777
Query: 387 LAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPL 446
L + P + P + F + SYF FL L L+ D +P
Sbjct: 778 LQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYV----------LMVDF---QP- 823
Query: 447 SRRGSMPSIVEWLILAWVSGLIWSEVKQLW----DMGLRE----YVHDMWNVIDFVTNSL 498
+PS E I W+ L+ E++QL+ + GL + Y D WN +D L
Sbjct: 824 -----VPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILL 878
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVY 556
+VA + R++ P L G + S I L+L++
Sbjct: 879 FVAGLTCRLI--------------------------PATLYPGRVILSLDFILFCLRLMH 912
Query: 557 IFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
IF+++ LGP + + RM+ D+ FF L +L ++ S G+
Sbjct: 913 IFTISKTLGPKIIIVKRMMKDV--FFFLFLLAVWVVSFGV 950
>BC112342-1|AAI12343.1| 1553|Homo sapiens TRPM2 protein protein.
Length = 1553
Score = 51.6 bits (118), Expect = 1e-05
Identities = 69/280 (24%), Positives = 117/280 (41%), Gaps = 61/280 (21%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVP---GFRRKNMLLQAAEMVRIGAM-FPLYS 386
L+LA++ + KFV+H +Q L +W+ + G R + + A ++ G + F
Sbjct: 718 LQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKR 777
Query: 387 LAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPL 446
L + P + P + F + SYF FL L L+ D +P
Sbjct: 778 LQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYV----------LMVDF---QP- 823
Query: 447 SRRGSMPSIVEWLILAWVSGLIWSEVKQLW----DMGLRE----YVHDMWNVIDFVTNSL 498
+PS E I W+ L+ E++QL+ + GL + Y D WN +D L
Sbjct: 824 -----VPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILL 878
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVY 556
+VA + R++ P L G + S I L+L++
Sbjct: 879 FVAGLTCRLI--------------------------PATLYPGRVILSLDFILFCLRLMH 912
Query: 557 IFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
IF+++ LGP + + RM+ D+ FF L +L ++ S G+
Sbjct: 913 IFTISKTLGPKIIIVKRMMKDV--FFFLFLLAVWVVSFGV 950
>AP001754-4|BAA95563.1| 1503|Homo sapiens transient receptor
potential-related channel 7, a novel putative Ca2+
channel p protein.
Length = 1503
Score = 51.6 bits (118), Expect = 1e-05
Identities = 69/280 (24%), Positives = 117/280 (41%), Gaps = 61/280 (21%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVP---GFRRKNMLLQAAEMVRIGAM-FPLYS 386
L+LA++ + KFV+H +Q L +W+ + G R + + A ++ G + F
Sbjct: 718 LQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKR 777
Query: 387 LAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPL 446
L + P + P + F + SYF FL L L+ D +P
Sbjct: 778 LQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYV----------LMVDF---QP- 823
Query: 447 SRRGSMPSIVEWLILAWVSGLIWSEVKQLW----DMGLRE----YVHDMWNVIDFVTNSL 498
+PS E I W+ L+ E++QL+ + GL + Y D WN +D L
Sbjct: 824 -----VPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILL 878
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVY 556
+VA + R++ P L G + S I L+L++
Sbjct: 879 FVAGLTCRLI--------------------------PATLYPGRVILSLDFILFCLRLMH 912
Query: 557 IFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
IF+++ LGP + + RM+ D+ FF L +L ++ S G+
Sbjct: 913 IFTISKTLGPKIIIVKRMMKDV--FFFLFLLAVWVVSFGV 950
>AJ878416-1|CAI47593.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2 protein.
Length = 1503
Score = 51.6 bits (118), Expect = 1e-05
Identities = 69/280 (24%), Positives = 117/280 (41%), Gaps = 61/280 (21%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVP---GFRRKNMLLQAAEMVRIGAM-FPLYS 386
L+LA++ + KFV+H +Q L +W+ + G R + + A ++ G + F
Sbjct: 718 LQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKR 777
Query: 387 LAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPL 446
L + P + P + F + SYF FL L L+ D +P
Sbjct: 778 LQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYV----------LMVDF---QP- 823
Query: 447 SRRGSMPSIVEWLILAWVSGLIWSEVKQLW----DMGLRE----YVHDMWNVIDFVTNSL 498
+PS E I W+ L+ E++QL+ + GL + Y D WN +D L
Sbjct: 824 -----VPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILL 878
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVY 556
+VA + R++ P L G + S I L+L++
Sbjct: 879 FVAGLTCRLI--------------------------PATLYPGRVILSLDFILFCLRLMH 912
Query: 557 IFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
IF+++ LGP + + RM+ D+ FF L +L ++ S G+
Sbjct: 913 IFTISKTLGPKIIIVKRMMKDV--FFFLFLLAVWVVSFGV 950
>AJ417076-1|CAD01139.1| 1449|Homo sapiens putative TRP cation
channel protein.
Length = 1449
Score = 51.6 bits (118), Expect = 1e-05
Identities = 69/280 (24%), Positives = 117/280 (41%), Gaps = 61/280 (21%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVP---GFRRKNMLLQAAEMVRIGAM-FPLYS 386
L+LA++ + KFV+H +Q L +W+ + G R + + A ++ G + F
Sbjct: 698 LQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKR 757
Query: 387 LAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPL 446
L + P + P + F + SYF FL L L+ D +P
Sbjct: 758 LQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYV----------LMVDF---QP- 803
Query: 447 SRRGSMPSIVEWLILAWVSGLIWSEVKQLW----DMGLRE----YVHDMWNVIDFVTNSL 498
+PS E I W+ L+ E++QL+ + GL + Y D WN +D L
Sbjct: 804 -----VPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILL 858
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVY 556
+VA + R++ P L G + S I L+L++
Sbjct: 859 FVAGLTCRLI--------------------------PATLYPGRVILSLDFILFCLRLMH 892
Query: 557 IFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
IF+++ LGP + + RM+ D+ FF L +L ++ S G+
Sbjct: 893 IFTISKTLGPKIIIVKRMMKDV--FFFLFLLAVWVVSFGV 930
>AB166746-1|BAD83706.1| 1289|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2,
striatum sh protein.
Length = 1289
Score = 51.6 bits (118), Expect = 1e-05
Identities = 69/280 (24%), Positives = 117/280 (41%), Gaps = 61/280 (21%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVP---GFRRKNMLLQAAEMVRIGAM-FPLYS 386
L+LA++ + KFV+H +Q L +W+ + G R + + A ++ G + F
Sbjct: 504 LQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKR 563
Query: 387 LAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPL 446
L + P + P + F + SYF FL L L+ D +P
Sbjct: 564 LQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYV----------LMVDF---QP- 609
Query: 447 SRRGSMPSIVEWLILAWVSGLIWSEVKQLW----DMGLRE----YVHDMWNVIDFVTNSL 498
+PS E I W+ L+ E++QL+ + GL + Y D WN +D L
Sbjct: 610 -----VPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILL 664
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVY 556
+VA + R++ P L G + S I L+L++
Sbjct: 665 FVAGLTCRLI--------------------------PATLYPGRVILSLDFILFCLRLMH 698
Query: 557 IFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
IF+++ LGP + + RM+ D+ FF L +L ++ S G+
Sbjct: 699 IFTISKTLGPKIIIVKRMMKDV--FFFLFLLAVWVVSFGV 736
>AB166745-1|BAD83705.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2, long
form ( protein.
Length = 1503
Score = 51.6 bits (118), Expect = 1e-05
Identities = 69/280 (24%), Positives = 117/280 (41%), Gaps = 61/280 (21%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVP---GFRRKNMLLQAAEMVRIGAM-FPLYS 386
L+LA++ + KFV+H +Q L +W+ + G R + + A ++ G + F
Sbjct: 718 LQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKR 777
Query: 387 LAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPL 446
L + P + P + F + SYF FL L L+ D +P
Sbjct: 778 LQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYV----------LMVDF---QP- 823
Query: 447 SRRGSMPSIVEWLILAWVSGLIWSEVKQLW----DMGLRE----YVHDMWNVIDFVTNSL 498
+PS E I W+ L+ E++QL+ + GL + Y D WN +D L
Sbjct: 824 -----VPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILL 878
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVY 556
+VA + R++ P L G + S I L+L++
Sbjct: 879 FVAGLTCRLI--------------------------PATLYPGRVILSLDFILFCLRLMH 912
Query: 557 IFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
IF+++ LGP + + RM+ D+ FF L +L ++ S G+
Sbjct: 913 IFTISKTLGPKIIIVKRMMKDV--FFFLFLLAVWVVSFGV 950
>AB001535-1|BAA34700.1| 1503|Homo sapiens KNP3 protein.
Length = 1503
Score = 51.6 bits (118), Expect = 1e-05
Identities = 69/280 (24%), Positives = 117/280 (41%), Gaps = 61/280 (21%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVP---GFRRKNMLLQAAEMVRIGAM-FPLYS 386
L+LA++ + KFV+H +Q L +W+ + G R + + A ++ G + F
Sbjct: 718 LQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKR 777
Query: 387 LAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPL 446
L + P + P + F + SYF FL L L+ D +P
Sbjct: 778 LQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYV----------LMVDF---QP- 823
Query: 447 SRRGSMPSIVEWLILAWVSGLIWSEVKQLW----DMGLRE----YVHDMWNVIDFVTNSL 498
+PS E I W+ L+ E++QL+ + GL + Y D WN +D L
Sbjct: 824 -----VPSWCECAIYLWLFSLVCEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILL 878
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVY 556
+VA + R++ P L G + S I L+L++
Sbjct: 879 FVAGLTCRLI--------------------------PATLYPGRVILSLDFILFCLRLMH 912
Query: 557 IFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
IF+++ LGP + + RM+ D+ FF L +L ++ S G+
Sbjct: 913 IFTISKTLGPKIIIVKRMMKDV--FFFLFLLAVWVVSFGV 950
>AB061779-1|BAB86335.1| 1095|Homo sapiens LTRPC6 protein.
Length = 1095
Score = 50.4 bits (115), Expect = 3e-05
Identities = 56/270 (20%), Positives = 113/270 (41%), Gaps = 37/270 (13%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYI 390
L+LA++ + F+A P VQ L+ WY + + ++ ++ PL ++
Sbjct: 648 LELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNRKIILCLFII------PLVGCGFV 701
Query: 391 AAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRG 450
+ V + + + ++ + +F + ++ + LL D
Sbjct: 702 SFRKKPVDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFH--------- 752
Query: 451 SMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSH 510
S+P E ++ + V L EV+Q + G+ Y D+WNV+D + ++A + R+ H
Sbjct: 753 SVPHPPELVLYSLVFVLFCDEVRQWYVNGVN-YFTDLWNVMDTLGLFYFIAGIVFRL--H 809
Query: 511 YQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVS 570
+ + G +F I +L+L++IF+V+ +LGP +
Sbjct: 810 SSNKSSLYSG-------------------RVIFCLDYIIFTLRLIHIFTVSRNLGPKIIM 850
Query: 571 LSRMVLDILKFFVLDILVIFAFSCGLNQLL 600
L RM++D+ F L + + AF +L
Sbjct: 851 LQRMLIDVFFFLFLFAVWMVAFGVARQGIL 880
>DQ139309-1|AAZ73614.1| 1104|Homo sapiens transient receptor
potential subfamily M member 8 protein.
Length = 1104
Score = 48.8 bits (111), Expect = 1e-04
Identities = 56/270 (20%), Positives = 113/270 (41%), Gaps = 37/270 (13%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYI 390
L+LA++ + F+A P VQ L+ WY + + ++ ++ PL ++
Sbjct: 657 LELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFII------PLVGCGFV 710
Query: 391 AAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRG 450
+ V + + + ++ + +F + ++ + LL D
Sbjct: 711 SFRKKPVDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFH--------- 761
Query: 451 SMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSH 510
S+P E ++ + V L EV+Q + G+ Y D+WNV+D + ++A + R+ H
Sbjct: 762 SVPHPPELVLYSLVFVLFCDEVRQWYVNGVN-YFTDLWNVMDTLGLFYFIAGIVFRL--H 818
Query: 511 YQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVS 570
+ + G +F I +L+L++IF+V+ +LGP +
Sbjct: 819 SSNKSSLYSG-------------------RVIFCLDYIIFTLRLIHIFTVSRNLGPKIIM 859
Query: 571 LSRMVLDILKFFVLDILVIFAFSCGLNQLL 600
L RM++D+ F L + + AF +L
Sbjct: 860 LQRMLIDVFFFLFLFAVWMVAFGVARQGIL 889
>AY328400-1|AAP92167.1| 1104|Homo sapiens transient receptor
potential subfamily M member 8 variant protein.
Length = 1104
Score = 48.8 bits (111), Expect = 1e-04
Identities = 56/270 (20%), Positives = 113/270 (41%), Gaps = 37/270 (13%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYI 390
L+LA++ + F+A P VQ L+ WY + + ++ ++ PL ++
Sbjct: 657 LELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFII------PLVGCGFV 710
Query: 391 AAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRG 450
+ V + + + ++ + +F + ++ + LL D
Sbjct: 711 SFRKKPVDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFH--------- 761
Query: 451 SMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSH 510
S+P E ++ + V L EV+Q + G+ Y D+WNV+D + ++A + R+ H
Sbjct: 762 SVPHPPELVLYSLVFVLFCDEVRQWYVNGVN-YFADLWNVMDTLGLFYFIAGIVFRL--H 818
Query: 511 YQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVS 570
+ + G +F I +L+L++IF+V+ +LGP +
Sbjct: 819 SSNKSSLYSG-------------------RVIFCLDYIIFTLRLIHIFTVSRNLGPKIIM 859
Query: 571 LSRMVLDILKFFVLDILVIFAFSCGLNQLL 600
L RM++D+ F L + + AF +L
Sbjct: 860 LQRMLIDVFFFLFLFAVWMVAFGVARQGIL 889
>AY090109-1|AAM10446.1| 1104|Homo sapiens transient receptor
potential cation channel protein protein.
Length = 1104
Score = 48.8 bits (111), Expect = 1e-04
Identities = 56/270 (20%), Positives = 113/270 (41%), Gaps = 37/270 (13%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVPGFRRKNMLLQAAEMVRIGAMFPLYSLAYI 390
L+LA++ + F+A P VQ L+ WY + + ++ ++ PL ++
Sbjct: 657 LELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFII------PLVGCGFV 710
Query: 391 AAPHSAVGRTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDVSHDEPLSRRG 450
+ V + + + ++ + +F + ++ + LL D
Sbjct: 711 SFRKKPVDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFH--------- 761
Query: 451 SMPSIVEWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSH 510
S+P E ++ + V L EV+Q + G+ Y D+WNV+D + ++A + R+ H
Sbjct: 762 SVPHPPELVLYSLVFVLFCDEVRQWYVNGVN-YFTDLWNVMDTLGLFYFIAGIVFRL--H 818
Query: 511 YQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVS 570
+ + G +F I +L+L++IF+V+ +LGP +
Sbjct: 819 SSNKSSLYSG-------------------RVIFCLDYIIFTLRLIHIFTVSRNLGPKIIM 859
Query: 571 LSRMVLDILKFFVLDILVIFAFSCGLNQLL 600
L RM++D+ F L + + AF +L
Sbjct: 860 LQRMLIDVFFFLFLFAVWMVAFGVARQGIL 889
>AF071787-1|AAC80000.1| 1533|Homo sapiens melastatin 1 protein.
Length = 1533
Score = 47.6 bits (108), Expect = 2e-04
Identities = 35/162 (21%), Positives = 75/162 (46%), Gaps = 30/162 (18%)
Query: 446 LSRRGSMPSIVEWLILAWVSGLIWSEVKQLW-------DMGLREYVHDMWNVIDFVTNSL 498
L R PS+ EW++++++ L +++++ ++ ++ + WN+ D V S
Sbjct: 780 LVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAIST 839
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIF 558
++ LR+ NQP M ++ IF ++++ IF
Sbjct: 840 FMIGAILRLQ---------------NQPY--------MGYGRVIYCVDIIFWYIRVLDIF 876
Query: 559 SVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL 600
VN +LGP + + +M++D+L F V+ ++V+ +F +L
Sbjct: 877 GVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAIL 918
>AB115502-1|BAC80204.1| 1527|Homo sapiens melastatin 1 splicing
variant protein.
Length = 1527
Score = 47.6 bits (108), Expect = 2e-04
Identities = 35/162 (21%), Positives = 75/162 (46%), Gaps = 30/162 (18%)
Query: 446 LSRRGSMPSIVEWLILAWVSGLIWSEVKQLW-------DMGLREYVHDMWNVIDFVTNSL 498
L R PS+ EW++++++ L +++++ ++ ++ + WN+ D V S
Sbjct: 774 LVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAIST 833
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIF 558
++ LR+ NQP M ++ IF ++++ IF
Sbjct: 834 FMIGAILRLQ---------------NQPY--------MGYGRVIYCVDIIFWYIRVLDIF 870
Query: 559 SVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL 600
VN +LGP + + +M++D+L F V+ ++V+ +F +L
Sbjct: 871 GVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAIL 912
>AB115501-1|BAC80203.1| 1533|Homo sapiens melastatin 1 protein.
Length = 1533
Score = 47.6 bits (108), Expect = 2e-04
Identities = 35/162 (21%), Positives = 75/162 (46%), Gaps = 30/162 (18%)
Query: 446 LSRRGSMPSIVEWLILAWVSGLIWSEVKQLW-------DMGLREYVHDMWNVIDFVTNSL 498
L R PS+ EW++++++ L +++++ ++ ++ + WN+ D V S
Sbjct: 780 LVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAIST 839
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIF 558
++ LR+ NQP M ++ IF ++++ IF
Sbjct: 840 FMIGAILRLQ---------------NQPY--------MGYGRVIYCVDIIFWYIRVLDIF 876
Query: 559 SVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL 600
VN +LGP + + +M++D+L F V+ ++V+ +F +L
Sbjct: 877 GVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAIL 918
>AB115499-1|BAC80201.1| 1533|Homo sapiens melastatin 1 protein.
Length = 1533
Score = 47.6 bits (108), Expect = 2e-04
Identities = 35/162 (21%), Positives = 75/162 (46%), Gaps = 30/162 (18%)
Query: 446 LSRRGSMPSIVEWLILAWVSGLIWSEVKQLW-------DMGLREYVHDMWNVIDFVTNSL 498
L R PS+ EW++++++ L +++++ ++ ++ + WN+ D V S
Sbjct: 780 LVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAIST 839
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIF 558
++ LR+ NQP M ++ IF ++++ IF
Sbjct: 840 FMIGAILRLQ---------------NQPY--------MGYGRVIYCVDIIFWYIRVLDIF 876
Query: 559 SVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL 600
VN +LGP + + +M++D+L F V+ ++V+ +F +L
Sbjct: 877 GVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAIL 918
>AB115498-1|BAC80200.1| 1533|Homo sapiens melastatin 1 protein.
Length = 1533
Score = 47.6 bits (108), Expect = 2e-04
Identities = 35/162 (21%), Positives = 75/162 (46%), Gaps = 30/162 (18%)
Query: 446 LSRRGSMPSIVEWLILAWVSGLIWSEVKQLW-------DMGLREYVHDMWNVIDFVTNSL 498
L R PS+ EW++++++ L +++++ ++ ++ + WN+ D V S
Sbjct: 780 LVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAIST 839
Query: 499 YVATVALRIVSHYQVRREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSSLKLVYIF 558
++ LR+ NQP M ++ IF ++++ IF
Sbjct: 840 FMIGAILRLQ---------------NQPY--------MGYGRVIYCVDIIFWYIRVLDIF 876
Query: 559 SVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL 600
VN +LGP + + +M++D+L F V+ ++V+ +F +L
Sbjct: 877 GVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAIL 918
>DQ084244-1|AAZ31363.1| 758|Homo sapiens polycystic kidney disease
2-like 1 variant protein.
Length = 758
Score = 46.0 bits (104), Expect = 7e-04
Identities = 47/201 (23%), Positives = 85/201 (42%), Gaps = 10/201 (4%)
Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLL--WDVSHDEPLSRRGSMPSIV 456
R R FI F ++A+ +F L ++ A GG + W + + + + +
Sbjct: 249 RGTRVVFIDFSVYNANINLFCVLRLVVEF---PATGGAIPSWQIRTVKLIRYVSNWDFFI 305
Query: 457 ---EWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513
E + ++ + E+ +L LR Y+ +WN++D V L + V I +V
Sbjct: 306 VGCEVIFCVFIFYYVVEEILELHIHRLR-YLSSIWNILDLVVILLSIVAVGFHIFRTLEV 364
Query: 514 RREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSS-LKLVYIFSVNPHLGPLQVSLS 572
R M LQ ++ +A N+F + +K+ S N + L +L+
Sbjct: 365 NRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLA 424
Query: 573 RMVLDILKFFVLDILVIFAFS 593
R DIL F V+ +V FA++
Sbjct: 425 RCAKDILGFAVMFFIVFFAYA 445
>BC025665-1|AAH25665.1| 805|Homo sapiens polycystic kidney disease
2-like 1 protein.
Length = 805
Score = 46.0 bits (104), Expect = 7e-04
Identities = 47/201 (23%), Positives = 85/201 (42%), Gaps = 10/201 (4%)
Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLL--WDVSHDEPLSRRGSMPSIV 456
R R FI F ++A+ +F L ++ A GG + W + + + + +
Sbjct: 296 RGTRVVFIDFSVYNANINLFCVLRLVVEF---PATGGAIPSWQIRTVKLIRYVSNWDFFI 352
Query: 457 ---EWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513
E + ++ + E+ +L LR Y+ +WN++D V L + V I +V
Sbjct: 353 VGCEVIFCVFIFYYVVEEILELHIHRLR-YLSSIWNILDLVVILLSIVAVGFHIFRTLEV 411
Query: 514 RREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSS-LKLVYIFSVNPHLGPLQVSLS 572
R M LQ ++ +A N+F + +K+ S N + L +L+
Sbjct: 412 NRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLA 471
Query: 573 RMVLDILKFFVLDILVIFAFS 593
R DIL F V+ +V FA++
Sbjct: 472 RCAKDILGFAVMFFIVFFAYA 492
>AL139819-2|CAH72822.1| 805|Homo sapiens polycystic kidney disease
2-like 1 protein.
Length = 805
Score = 46.0 bits (104), Expect = 7e-04
Identities = 47/201 (23%), Positives = 85/201 (42%), Gaps = 10/201 (4%)
Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLL--WDVSHDEPLSRRGSMPSIV 456
R R FI F ++A+ +F L ++ A GG + W + + + + +
Sbjct: 296 RGTRVVFIDFSVYNANINLFCVLRLVVEF---PATGGAIPSWQIRTVKLIRYVSNWDFFI 352
Query: 457 ---EWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513
E + ++ + E+ +L LR Y+ +WN++D V L + V I +V
Sbjct: 353 VGCEVIFCVFIFYYVVEEILELHIHRLR-YLSSIWNILDLVVILLSIVAVGFHIFRTLEV 411
Query: 514 RREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSS-LKLVYIFSVNPHLGPLQVSLS 572
R M LQ ++ +A N+F + +K+ S N + L +L+
Sbjct: 412 NRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLA 471
Query: 573 RMVLDILKFFVLDILVIFAFS 593
R DIL F V+ +V FA++
Sbjct: 472 RCAKDILGFAVMFFIVFFAYA 492
>AF153474-1|AAF28108.1| 805|Homo sapiens polycystic kidney disease
2-like protein protein.
Length = 805
Score = 46.0 bits (104), Expect = 7e-04
Identities = 47/201 (23%), Positives = 85/201 (42%), Gaps = 10/201 (4%)
Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLL--WDVSHDEPLSRRGSMPSIV 456
R R FI F ++A+ +F L ++ A GG + W + + + + +
Sbjct: 296 RGTRVVFIDFSVYNANINLFCVLRLVVEF---PATGGAIPSWQIRTVKLIRYVSNWDFFI 352
Query: 457 ---EWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513
E + ++ + E+ +L LR Y+ +WN++D V L + V I +V
Sbjct: 353 VGCEVIFCVFIFYYVVEEILELHIHRLR-YLSSIWNILDLVVILLSIVAVGFHIFRTLEV 411
Query: 514 RREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSS-LKLVYIFSVNPHLGPLQVSLS 572
R M LQ ++ +A N+F + +K+ S N + L +L+
Sbjct: 412 NRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLA 471
Query: 573 RMVLDILKFFVLDILVIFAFS 593
R DIL F V+ +V FA++
Sbjct: 472 RCAKDILGFAVMFFIVFFAYA 492
>AF094827-1|AAD08695.1| 710|Homo sapiens PKD2L protein.
Length = 710
Score = 46.0 bits (104), Expect = 7e-04
Identities = 47/201 (23%), Positives = 85/201 (42%), Gaps = 10/201 (4%)
Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLL--WDVSHDEPLSRRGSMPSIV 456
R R FI F ++A+ +F L ++ A GG + W + + + + +
Sbjct: 201 RGTRVVFIDFSVYNANINLFCVLRLVVEF---PATGGAIPSWQIRTVKLIRYVSNWDFFI 257
Query: 457 ---EWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513
E + ++ + E+ +L LR Y+ +WN++D V L + V I +V
Sbjct: 258 VGCEVIFCVFIFYYVVEEILELHIHRLR-YLSSIWNILDLVVILLSIVAVGFHIFRTLEV 316
Query: 514 RREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSS-LKLVYIFSVNPHLGPLQVSLS 572
R M LQ ++ +A N+F + +K+ S N + L +L+
Sbjct: 317 NRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLA 376
Query: 573 RMVLDILKFFVLDILVIFAFS 593
R DIL F V+ +V FA++
Sbjct: 377 RCAKDILGFAVMFFIVFFAYA 397
>AF053316-1|AAD51859.1| 763|Homo sapiens polycystin-2 homolog
protein.
Length = 763
Score = 46.0 bits (104), Expect = 7e-04
Identities = 47/201 (23%), Positives = 85/201 (42%), Gaps = 10/201 (4%)
Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLL--WDVSHDEPLSRRGSMPSIV 456
R R FI F ++A+ +F L ++ A GG + W + + + + +
Sbjct: 254 RGTRVVFIDFSVYNANINLFCVLRLVVEF---PATGGAIPSWQIRTVKLIRYVSNWDFFI 310
Query: 457 ---EWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513
E + ++ + E+ +L LR Y+ +WN++D V L + V I +V
Sbjct: 311 VGCEVIFCVFIFYYVVEEILELHIHRLR-YLSSIWNILDLVVILLSIVAVGFHIFRTLEV 369
Query: 514 RREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSS-LKLVYIFSVNPHLGPLQVSLS 572
R M LQ ++ +A N+F + +K+ S N + L +L+
Sbjct: 370 NRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLA 429
Query: 573 RMVLDILKFFVLDILVIFAFS 593
R DIL F V+ +V FA++
Sbjct: 430 RCAKDILGFAVMFFIVFFAYA 450
>AF073481-1|AAD41638.1| 805|Homo sapiens polycystin-L protein.
Length = 805
Score = 45.6 bits (103), Expect = 0.001
Identities = 47/201 (23%), Positives = 85/201 (42%), Gaps = 10/201 (4%)
Query: 399 RTLRKPFIKFLCHSASYFMFLFLLILASQRIETAPGGLL--WDVSHDEPLSRRGSMPSIV 456
R R FI F ++A+ +F L ++ A GG + W + + + + +
Sbjct: 296 RGTRVVFIDFSVYNANINLFCVLRLVVEF---PATGGAIPSWQIRTVKLIRYVSNWDFFI 352
Query: 457 ---EWLILAWVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQV 513
E + ++ + E+ +L LR Y+ +WN++D V L + V I +V
Sbjct: 353 VGCEVIFCVFIFYYVVEEILELHIHRLR-YLSSIWNILDLVIILLSIVAVGFHIFRTLEV 411
Query: 514 RREMAMGLQWNQPREKWDAWDPMLLSEGLFSAANIFSS-LKLVYIFSVNPHLGPLQVSLS 572
R M LQ ++ +A N+F + +K+ S N + L +L+
Sbjct: 412 NRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLA 471
Query: 573 RMVLDILKFFVLDILVIFAFS 593
R DIL F V+ +V FA++
Sbjct: 472 RCAKDILGFAVMFFIVFFAYA 492
>AF092170-1|AAD16101.1| 665|Homo sapiens polycystic kidney disease
2 related protein protein.
Length = 665
Score = 43.2 bits (97), Expect = 0.005
Identities = 44/192 (22%), Positives = 82/192 (42%), Gaps = 4/192 (2%)
Query: 405 FIKFLCHSASYFMFLFLLILASQRIETAPGGLLWDV-SHDEPLSRR-GSMPSIVEWLILA 462
FI F ++A+ +F L ++ +L + S +PL ++ G + E +
Sbjct: 189 FIDFSVYNANINLFCVLRLVVEFPANRRCHPILANPHSQADPLCQQLGFLIVGCEVIFCV 248
Query: 463 WVSGLIWSEVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQ 522
+ + E+ +L LR Y+ +WN++D V L + V I +V R M LQ
Sbjct: 249 LIFYYVVEEILELHIHRLR-YLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQ 307
Query: 523 WNQPREKWDAWDPMLLSEGLFSAANIFSS-LKLVYIFSVNPHLGPLQVSLSRMVLDILKF 581
++ +A N+F + +K+ N + L +++R DIL F
Sbjct: 308 QPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYIRFNKTMTQLSSTMARCAKDILGF 367
Query: 582 FVLDILVIFAFS 593
V+ +V FA++
Sbjct: 368 AVMFFIVFFAYA 379
>AC079341-5|AAY40971.1| 72|Homo sapiens unknown protein.
Length = 72
Score = 42.7 bits (96), Expect = 0.006
Identities = 20/43 (46%), Positives = 29/43 (67%)
Query: 765 IMRNLVRRYVTVQQRRAESGGVTEDDVNEIKQDVSAFRCELVE 807
IM+ L++RYV Q E+ V E ++ EIKQD+S+ R EL+E
Sbjct: 2 IMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLE 44
>BC126342-1|AAI26343.1| 682|Homo sapiens TRPM8 protein protein.
Length = 682
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/59 (32%), Positives = 34/59 (57%)
Query: 542 LFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGLNQLL 600
+F I +L+L++IF+V+ +LGP + L RM++D+ F L + + AF +L
Sbjct: 409 IFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGIL 467
>AY603182-1|AAT12288.1| 846|Homo sapiens TRPM2-S protein.
Length = 846
Score = 38.3 bits (85), Expect = 0.14
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 4/95 (4%)
Query: 331 LKLAIKLRQKKFVAHPNVQQLLASIWYESVP---GFRRKNMLLQAAEMVRIGAM-FPLYS 386
L+LA++ + KFV+H +Q L +W+ + G R + + A ++ G + F
Sbjct: 718 LQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKR 777
Query: 387 LAYIAAPHSAVGRTLRKPFIKFLCHSASYFMFLFL 421
L + P + P + F + SYF FL L
Sbjct: 778 LQDVGTPAARARAFFTAPVVVFHLNILSYFAFLCL 812
>BC093789-1|AAH93789.1| 1165|Homo sapiens transient receptor potential
cation channel, subfamily M, member 5 protein.
Length = 1165
Score = 36.7 bits (81), Expect = 0.42
Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 8/87 (9%)
Query: 693 HSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGHA 752
+++Q++ AD+ WKF R L + Y E APP +L S SL L+R A
Sbjct: 980 YTFQVVQGNADMFWKFQRYNLIVEYHERPALAPP--FILLSHLSLT-----LRRVFKKEA 1032
Query: 753 RAKREHM-RTIRAIMRNLVRRYVTVQQ 778
KREH+ R + + V + TVQ+
Sbjct: 1033 EHKREHLERDLPDPLDQKVVTWETVQK 1059
Score = 32.7 bits (71), Expect = 6.9
Identities = 15/46 (32%), Positives = 30/46 (65%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+L+L++IF+++ LGP + + RM+ D+ FF L L ++ + G+
Sbjct: 846 TLRLIHIFAIHKQLGPKIIVVERMMKDV--FFFLFFLSVWLVAYGV 889
>BC093787-1|AAH93787.1| 1165|Homo sapiens transient receptor potential
cation channel, subfamily M, member 5 protein.
Length = 1165
Score = 36.7 bits (81), Expect = 0.42
Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 8/87 (9%)
Query: 693 HSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGHA 752
+++Q++ AD+ WKF R L + Y E APP +L S SL L+R A
Sbjct: 980 YTFQVVQGNADMFWKFQRYNLIVEYHERPALAPP--FILLSHLSLT-----LRRVFKKEA 1032
Query: 753 RAKREHM-RTIRAIMRNLVRRYVTVQQ 778
KREH+ R + + V + TVQ+
Sbjct: 1033 EHKREHLERDLPDPLDQKVVTWETVQK 1059
Score = 32.7 bits (71), Expect = 6.9
Identities = 15/46 (32%), Positives = 30/46 (65%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+L+L++IF+++ LGP + + RM+ D+ FF L L ++ + G+
Sbjct: 846 TLRLIHIFAIHKQLGPKIIVVERMMKDV--FFFLFFLSVWLVAYGV 889
>AJ270996-1|CAB66342.1| 1159|Homo sapiens LTRPC5 protein protein.
Length = 1159
Score = 36.7 bits (81), Expect = 0.42
Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 8/87 (9%)
Query: 693 HSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGHA 752
+++Q++ AD+ WKF R L + Y E APP +L S SL L+R A
Sbjct: 974 YTFQVVQGNADMFWKFQRYNLIVEYHERPALAPP--FILLSHLSLT-----LRRVFKKEA 1026
Query: 753 RAKREHM-RTIRAIMRNLVRRYVTVQQ 778
KREH+ R + + V + TVQ+
Sbjct: 1027 EHKREHLERDLPDPLDQKVVTWETVQK 1053
Score = 32.7 bits (71), Expect = 6.9
Identities = 15/46 (32%), Positives = 30/46 (65%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+L+L++IF+++ LGP + + RM+ D+ FF L L ++ + G+
Sbjct: 840 TLRLIHIFAIHKQLGPKIIVVERMMKDV--FFFLFFLSVWLVAYGV 883
>AF177473-1|AAF26288.1| 1165|Homo sapiens MTR1 protein.
Length = 1165
Score = 36.7 bits (81), Expect = 0.42
Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 8/87 (9%)
Query: 693 HSYQLISERADVEWKFARSKLWISYFEEGGTAPPPFNVLPSPKSLLYAWRWLQRRLCGHA 752
+++Q++ AD+ WKF R L + Y E APP +L S SL L+R A
Sbjct: 980 YTFQVVQGNADMFWKFQRYNLIVEYHERPALAPP--FILLSHLSLT-----LRRVFKKEA 1032
Query: 753 RAKREHM-RTIRAIMRNLVRRYVTVQQ 778
KREH+ R + + V + TVQ+
Sbjct: 1033 EHKREHLERDLPDPLDQKVVTWETVQK 1059
Score = 32.7 bits (71), Expect = 6.9
Identities = 15/46 (32%), Positives = 30/46 (65%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+L+L++IF+++ LGP + + RM+ D+ FF L L ++ + G+
Sbjct: 846 TLRLIHIFAIHKQLGPKIIVVERMMKDV--FFFLFFLSVWLVAYGV 889
>AY032950-1|AAK44211.1| 1865|Homo sapiens LTRPC7 protein.
Length = 1865
Score = 36.3 bits (80), Expect = 0.56
Identities = 33/154 (21%), Positives = 73/154 (47%), Gaps = 15/154 (9%)
Query: 452 MPSIVEWLILAWVSGLIWSEVKQLW--DMGLREYVHDMWNVIDFVTNSLYVATVALRIVS 509
+PS+ EW+++A++ +V++++ + G +W D+ S +A I+S
Sbjct: 881 LPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVW-FSDYFNISDTIA-----IIS 934
Query: 510 HYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVYIFSVNPHLGPL 567
+ + + G +WN +A+D + G ++ IF ++L+ +VN GP
Sbjct: 935 FF-IGFGLRFGAKWNFA----NAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPY 989
Query: 568 QVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLW 601
+ + +MV ++ V+ LV+ +F +L+
Sbjct: 990 VMMIGKMVANMFYIVVIMALVLLSFGVPRKAILY 1023
>AF346629-1|AAK19738.2| 1864|Homo sapiens channel-kinase 1 protein.
Length = 1864
Score = 36.3 bits (80), Expect = 0.56
Identities = 33/154 (21%), Positives = 73/154 (47%), Gaps = 15/154 (9%)
Query: 452 MPSIVEWLILAWVSGLIWSEVKQLW--DMGLREYVHDMWNVIDFVTNSLYVATVALRIVS 509
+PS+ EW+++A++ +V++++ + G +W D+ S +A I+S
Sbjct: 881 LPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVW-FSDYFNISDTIA-----IIS 934
Query: 510 HYQVRREMAMGLQWNQPREKWDAWDPMLLSEG--LFSAANIFSSLKLVYIFSVNPHLGPL 567
+ + + G +WN +A+D + G ++ IF ++L+ +VN GP
Sbjct: 935 FF-IGFGLRFGAKWNFA----NAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPY 989
Query: 568 QVSLSRMVLDILKFFVLDILVIFAFSCGLNQLLW 601
+ + +MV ++ V+ LV+ +F +L+
Sbjct: 990 VMMIGKMVANMFYIVVIMALVLLSFGVPRKAILY 1023
>AF182034-1|AAF65622.1| 624|Homo sapiens polycystic kidney
disease-like 2 protein protein.
Length = 624
Score = 36.3 bits (80), Expect = 0.56
Identities = 29/127 (22%), Positives = 62/127 (48%), Gaps = 8/127 (6%)
Query: 471 EVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKW 530
EVK++ + Y +WN ++ + L + VA+ ++Y V+ + +G Q + EK+
Sbjct: 300 EVKKIKEFK-SAYFKSIWNWLELLL--LLLCFVAVSFNTYYNVQIFLLLG-QLLKSTEKY 355
Query: 531 DAWDPM----LLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDI 586
+ + + + + F+ +K+ S N + L +LSR V DI+ F ++
Sbjct: 356 SDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFF 415
Query: 587 LVIFAFS 593
++ FA++
Sbjct: 416 IIFFAYA 422
>AF118125-1|AAD46478.1| 609|Homo sapiens polycystin-2-like protein
protein.
Length = 609
Score = 36.3 bits (80), Expect = 0.56
Identities = 29/127 (22%), Positives = 62/127 (48%), Gaps = 8/127 (6%)
Query: 471 EVKQLWDMGLREYVHDMWNVIDFVTNSLYVATVALRIVSHYQVRREMAMGLQWNQPREKW 530
EVK++ + Y +WN ++ + L + VA+ ++Y V+ + +G Q + EK+
Sbjct: 300 EVKKIKEFK-SAYFKSIWNWLELLL--LLLCFVAVSFNTYYNVQIFLLLG-QLLKSTEKY 355
Query: 531 DAWDPM----LLSEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDI 586
+ + + + + F+ +K+ S N + L +LSR V DI+ F ++
Sbjct: 356 SDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFF 415
Query: 587 LVIFAFS 593
++ FA++
Sbjct: 416 IIFFAYA 422
>U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein.
Length = 4377
Score = 35.9 bits (79), Expect = 0.74
Identities = 16/31 (51%), Positives = 24/31 (77%)
Query: 174 TFTSDITPLILAAHRDSYEIIKLLLDRGAQL 204
T +DITPL +A+ R + ++KLLLDRGA++
Sbjct: 264 TARNDITPLHVASKRGNANMVKLLLDRGAKI 294
>AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 35.9 bits (79), Expect = 0.74
Identities = 16/31 (51%), Positives = 24/31 (77%)
Query: 174 TFTSDITPLILAAHRDSYEIIKLLLDRGAQL 204
T +DITPL +A+ R + ++KLLLDRGA++
Sbjct: 264 TARNDITPLHVASKRGNANMVKLLLDRGAKI 294
>AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 35.9 bits (79), Expect = 0.74
Identities = 16/31 (51%), Positives = 24/31 (77%)
Query: 174 TFTSDITPLILAAHRDSYEIIKLLLDRGAQL 204
T +DITPL +A+ R + ++KLLLDRGA++
Sbjct: 264 TARNDITPLHVASKRGNANMVKLLLDRGAKI 294
>AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 35.9 bits (79), Expect = 0.74
Identities = 16/31 (51%), Positives = 24/31 (77%)
Query: 174 TFTSDITPLILAAHRDSYEIIKLLLDRGAQL 204
T +DITPL +A+ R + ++KLLLDRGA++
Sbjct: 264 TARNDITPLHVASKRGNANMVKLLLDRGAKI 294
>AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat
containing protein protein.
Length = 1101
Score = 35.1 bits (77), Expect = 1.3
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 11/81 (13%)
Query: 131 RDALLHAISEEFVEAVEALLDHEERTRKPGEP---NSWEALPPETATFTSDITPLILAAH 187
+ AL+ A S + E V LLD E+ + E NS+++L ETA L AA
Sbjct: 93 QQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETA--------LTAAAG 144
Query: 188 RDSYEIIKLLLDRGAQLPEPH 208
R E+ +LLL++GA + +P+
Sbjct: 145 RGKLEVCRLLLEQGAAVAQPN 165
>AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein.
Length = 1864
Score = 35.1 bits (77), Expect = 1.3
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 11/81 (13%)
Query: 131 RDALLHAISEEFVEAVEALLDHEERTRKPGEP---NSWEALPPETATFTSDITPLILAAH 187
+ AL+ A S + E V LLD E+ + E NS+++L ETA L AA
Sbjct: 866 QQALIAAASMGYTEIVSYLLDLPEKDEEEVERAQINSFDSLWGETA--------LTAAAG 917
Query: 188 RDSYEIIKLLLDRGAQLPEPH 208
R E+ +LLL++GA + +P+
Sbjct: 918 RGKLEVCRLLLEQGAAVAQPN 938
>BC132727-1|AAI32728.1| 1214|Homo sapiens transient receptor
potential cation channel, subfamily M, member 4 protein.
Length = 1214
Score = 33.5 bits (73), Expect = 3.9
Identities = 17/46 (36%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+++L++IF+VN LGP V +S+M+ D+ FF L L ++ + G+
Sbjct: 903 TVRLLHIFTVNKQLGPKIVIVSKMMKDV--FFFLFFLGVWLVAYGV 946
>AY297046-1|AAP44475.1| 1069|Homo sapiens transient receptor
potential cation channel subfamily M member 4 splice
variant protein.
Length = 1069
Score = 33.5 bits (73), Expect = 3.9
Identities = 17/46 (36%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+++L++IF+VN LGP V +S+M+ D+ FF L L ++ + G+
Sbjct: 758 TVRLLHIFTVNKQLGPKIVIVSKMMKDV--FFFLFFLGVWLVAYGV 801
>AY297045-1|AAP44474.1| 1214|Homo sapiens transient receptor
potential cation channel subfamily M member 4 splice
variant protein.
Length = 1214
Score = 33.5 bits (73), Expect = 3.9
Identities = 17/46 (36%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+++L++IF+VN LGP V +S+M+ D+ FF L L ++ + G+
Sbjct: 903 TVRLLHIFTVNKQLGPKIVIVSKMMKDV--FFFLFFLGVWLVAYGV 946
>AY297044-1|AAP44473.1| 1040|Homo sapiens transient receptor
potential cation channel subfamily M member 4 splice
variant protein.
Length = 1040
Score = 33.5 bits (73), Expect = 3.9
Identities = 17/46 (36%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+++L++IF+VN LGP V +S+M+ D+ FF L L ++ + G+
Sbjct: 729 TVRLLHIFTVNKQLGPKIVIVSKMMKDV--FFFLFFLGVWLVAYGV 772
>AY046396-1|AAL02142.1| 1040|Homo sapiens TRP-related cation influx
channel protein.
Length = 1040
Score = 33.5 bits (73), Expect = 3.9
Identities = 17/46 (36%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+++L++IF+VN LGP V +S+M+ D+ FF L L ++ + G+
Sbjct: 729 TVRLLHIFTVNKQLGPKIVIVSKMMKDV--FFFLFFLGVWLVAYGV 772
>AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 518
Score = 33.5 bits (73), Expect = 3.9
Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 166 EALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCGCDDCVRSRREDS 225
EA AT + TPL LA ++++LLL GA + H + CG + ++ +D+
Sbjct: 100 EAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSM-CGWNSLHQASFQDN 158
>AK000048-1|BAA90907.1| 1016|Homo sapiens protein ( Homo sapiens
cDNA FLJ20041 fis, clone COL00423. ).
Length = 1016
Score = 33.5 bits (73), Expect = 3.9
Identities = 17/46 (36%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+++L++IF+VN LGP V +S+M+ D+ FF L L ++ + G+
Sbjct: 729 TVRLLHIFTVNKQLGPKIVIVSKMMKDV--FFFLFFLGVWLVAYGV 772
>AJ575813-1|CAE05941.1| 1214|Homo sapiens transient receptor
potential ion channel melastatin subgroup member 4
protein protein.
Length = 1214
Score = 33.5 bits (73), Expect = 3.9
Identities = 17/46 (36%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+++L++IF+VN LGP V +S+M+ D+ FF L L ++ + G+
Sbjct: 903 TVRLLHIFTVNKQLGPKIVIVSKMMKDV--FFFLFFLGVWLVAYGV 946
>AF497623-1|AAM18083.1| 1214|Homo sapiens cation channel TRPM4B
protein.
Length = 1214
Score = 33.5 bits (73), Expect = 3.9
Identities = 17/46 (36%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 551 SLKLVYIFSVNPHLGPLQVSLSRMVLDILKFFVLDILVIFAFSCGL 596
+++L++IF+VN LGP V +S+M+ D+ FF L L ++ + G+
Sbjct: 903 TVRLLHIFTVNKQLGPKIVIVSKMMKDV--FFFLFFLGVWLVAYGV 946
>Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein.
Length = 3925
Score = 33.1 bits (72), Expect = 5.2
Identities = 15/31 (48%), Positives = 22/31 (70%)
Query: 174 TFTSDITPLILAAHRDSYEIIKLLLDRGAQL 204
T + ITPL +A+ R + ++KLLLDRG Q+
Sbjct: 262 TARNGITPLHVASKRGNTNMVKLLLDRGGQI 292
>X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein.
Length = 1872
Score = 33.1 bits (72), Expect = 5.2
Identities = 15/31 (48%), Positives = 22/31 (70%)
Query: 174 TFTSDITPLILAAHRDSYEIIKLLLDRGAQL 204
T + ITPL +A+ R + ++KLLLDRG Q+
Sbjct: 262 TARNGITPLHVASKRGNTNMVKLLLDRGGQI 292
>BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein
protein.
Length = 1863
Score = 33.1 bits (72), Expect = 5.2
Identities = 15/31 (48%), Positives = 22/31 (70%)
Query: 174 TFTSDITPLILAAHRDSYEIIKLLLDRGAQL 204
T + ITPL +A+ R + ++KLLLDRG Q+
Sbjct: 241 TARNGITPLHVASKRGNTNMVKLLLDRGGQI 271
>X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2)
protein.
Length = 1719
Score = 32.7 bits (71), Expect = 6.9
Identities = 14/26 (53%), Positives = 21/26 (80%)
Query: 179 ITPLILAAHRDSYEIIKLLLDRGAQL 204
ITPL +A+ R + +++LLLDRGAQ+
Sbjct: 240 ITPLHIASRRGNVIMVRLLLDRGAQI 265
>X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for
ankyrin (variant 2.1). ).
Length = 1881
Score = 32.7 bits (71), Expect = 6.9
Identities = 14/26 (53%), Positives = 21/26 (80%)
Query: 179 ITPLILAAHRDSYEIIKLLLDRGAQL 204
ITPL +A+ R + +++LLLDRGAQ+
Sbjct: 240 ITPLHIASRRGNVIMVRLLLDRGAQI 265
>U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein.
Length = 1856
Score = 32.7 bits (71), Expect = 6.9
Identities = 14/26 (53%), Positives = 21/26 (80%)
Query: 179 ITPLILAAHRDSYEIIKLLLDRGAQL 204
ITPL +A+ R + +++LLLDRGAQ+
Sbjct: 207 ITPLHIASRRGNVIMVRLLLDRGAQI 232
>M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein.
Length = 1880
Score = 32.7 bits (71), Expect = 6.9
Identities = 14/26 (53%), Positives = 21/26 (80%)
Query: 179 ITPLILAAHRDSYEIIKLLLDRGAQL 204
ITPL +A+ R + +++LLLDRGAQ+
Sbjct: 240 ITPLHIASRRGNVIMVRLLLDRGAQI 265
>BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein.
Length = 553
Score = 32.7 bits (71), Expect = 6.9
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 166 EALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCG 213
EA AT + TPL LA ++++LLL GA + H + CG
Sbjct: 135 EAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSM-CG 181
>BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 32.7 bits (71), Expect = 6.9
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 166 EALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCG 213
EA AT + TPL LA ++++LLL GA + H + CG
Sbjct: 100 EAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSM-CG 146
>BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 32.7 bits (71), Expect = 6.9
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 166 EALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCG 213
EA AT + TPL LA ++++LLL GA + H + CG
Sbjct: 100 EAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSM-CG 146
>AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 512
Score = 32.7 bits (71), Expect = 6.9
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 166 EALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCG 213
EA AT + TPL LA ++++LLL GA + H + CG
Sbjct: 94 EAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSM-CG 140
>AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ10123 fis, clone HEMBA1002939, weakly similar to
ANKYRIN R. ).
Length = 518
Score = 32.7 bits (71), Expect = 6.9
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 166 EALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCG 213
EA AT + TPL LA ++++LLL GA + H + CG
Sbjct: 100 EAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSM-CG 146
>AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein.
Length = 518
Score = 32.7 bits (71), Expect = 6.9
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 166 EALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCG 213
EA AT + TPL LA ++++LLL GA + H + CG
Sbjct: 100 EAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSM-CG 146
>AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein.
Length = 326
Score = 32.7 bits (71), Expect = 6.9
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 166 EALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCG 213
EA AT + TPL LA ++++LLL GA + H + CG
Sbjct: 100 EAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSM-CG 146
>AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 340
Score = 32.7 bits (71), Expect = 6.9
Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 166 EALPPETATFTSDITPLILAAHRDSYEIIKLLLDRGAQLPEPHDVRCG 213
EA AT + TPL LA ++++LLL GA + H + CG
Sbjct: 110 EAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSM-CG 156
>AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4
variant protein.
Length = 1899
Score = 32.7 bits (71), Expect = 6.9
Identities = 14/26 (53%), Positives = 21/26 (80%)
Query: 179 ITPLILAAHRDSYEIIKLLLDRGAQL 204
ITPL +A+ R + +++LLLDRGAQ+
Sbjct: 275 ITPLHIASRRGNVIMVRLLLDRGAQI 300
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.136 0.417
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 145,441,601
Number of Sequences: 224733
Number of extensions: 6065472
Number of successful extensions: 14534
Number of sequences better than 10.0: 127
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 13782
Number of HSP's gapped (non-prelim): 459
length of query: 1024
length of database: 73,234,838
effective HSP length: 97
effective length of query: 927
effective length of database: 51,435,737
effective search space: 47680928199
effective search space used: 47680928199
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 70 (32.3 bits)
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