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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001084-TA|BGIBMGA001084-PA|IPR003701|DNA repair
exonuclease, IPR004843|Metallophosphoesterase, IPR007281|Mre11,
DNA-binding
         (628 letters)

Database: fruitfly 
           52,641 sequences; 24,830,863 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AF132144-1|AAD33591.1|  620|Drosophila melanogaster endo/exonucl...   449   e-126
AE014134-2061|AAF53093.1|  620|Drosophila melanogaster CG16928-P...   449   e-126
AE014297-1413|AAF54724.2|  573|Drosophila melanogaster CG12213-P...    33   1.6  
AE014297-1412|AAN13537.1|  506|Drosophila melanogaster CG12213-P...    33   1.6  
X53992-1|CAA37939.1| 1645|Drosophila melanogaster betaH spectrin...    31   3.6  
BT011336-1|AAR96128.1|  914|Drosophila melanogaster SD02170p pro...    31   3.6  
BT001607-1|AAN71362.1|  604|Drosophila melanogaster RE31467p pro...    31   3.6  
AE014296-651|AAF47766.1| 4097|Drosophila melanogaster CG12008-PA...    31   3.6  
AE014296-650|AAS64958.1| 4118|Drosophila melanogaster CG12008-PB...    31   3.6  
AE014296-649|AAS64957.1| 4207|Drosophila melanogaster CG12008-PC...    31   3.6  
AE013599-3654|AAM68265.1|  904|Drosophila melanogaster CG5411-PB...    31   3.6  
AE013599-3653|AAM68264.1|  805|Drosophila melanogaster CG5411-PD...    31   3.6  
AE013599-3651|AAM68263.1|  914|Drosophila melanogaster CG5411-PA...    31   3.6  
AM294540-1|CAL26523.1|  431|Drosophila melanogaster CG3975 protein.    31   6.3  
AF201919-1|AAF71697.1|   97|Drosophila melanogaster CRC-D protein.     31   6.3  
AE014134-3388|ABC65922.1|  105|Drosophila melanogaster CG8669-PD...    31   6.3  

>AF132144-1|AAD33591.1|  620|Drosophila melanogaster
           endo/exonuclease Mre11 protein.
          Length = 620

 Score =  449 bits (1106), Expect = e-126
 Identities = 235/506 (46%), Positives = 320/506 (63%), Gaps = 23/506 (4%)

Query: 12  DDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQAKPSV 71
           D+ +RIL+A+D HLG+ E D VRGEDSF AFEE+L LAV  DVD+ILLGGDLF  A PS 
Sbjct: 12  DNVIRILVATDNHLGYGEKDAVRGEDSFTAFEEILELAVSEDVDMILLGGDLFHDAVPSQ 71

Query: 72  NCMFKCTEIIRKYCLGDKPVSIELLSDQIKNF----SRTVNYEDPNLNISYPILSIHGNH 127
           N + KC E++R+Y  GD+PVS+E+LSDQ + F    +++VNYEDPNLNI+ P+ SIHGNH
Sbjct: 72  NALHKCIELLRRYTFGDRPVSLEILSDQGQCFHNAVNQSVNYEDPNLNIAIPVFSIHGNH 131

Query: 128 DDPVGQGSVSSLDILSITGLVNYFGKWTDYTHVRISPVLLQKGLTRLALYGLSHLKDQRL 187
           DDP G G +SSLD+LS +GLVNYFG+WTD T V ISPVL++KG ++LALYGLSH+ D RL
Sbjct: 132 DDPSGFGRLSSLDLLSTSGLVNYFGRWTDLTQVEISPVLMRKGESQLALYGLSHIHDGRL 191

Query: 188 SRLFAEKKVEMERPD------------ETLDWFNLFVLHQNHADRGHSNYIPEGVLPNFL 235
           +RL  + KV+   P+            E  DWF+L V+HQN ADRG  NY+PE +LP+FL
Sbjct: 192 ARLIKDFKVKFNCPENVANGEDGNESKEEEDWFHLLVVHQNRADRGPKNYLPEDLLPSFL 251

Query: 236 DLVVWGHEHDSHICPMKGNKTEKDSFFVVQPGSTVATSLAAGEALPKHCGLLEIHKGNFK 295
            LV+WGHEHD   C ++  +  K  F+V QPGS+V TSL+ GEA  KH GLLEI+KG FK
Sbjct: 252 HLVIWGHEHD---CRIEPEENAKKRFYVSQPGSSVPTSLSEGEAKKKHVGLLEIYKGKFK 308

Query: 296 LTPLPLQTVRPFIFKTIVLSE--ENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTADL 353
           L PLPL+TVRPF+++++VL++  + +G  + + + KV +F + RV   I+ A    T   
Sbjct: 309 LKPLPLETVRPFVYESVVLADHADELGLVEGDASTKVFKFAQERVEAMIERAVAQHTGHP 368

Query: 354 RQPLLPLIRLSIFYERESQNFNRIRFGQNFNGLVANPNDLLIMXXXXXXXXXXXXXXXXX 413
           +QP LPLIRL + Y  ES  FN IRFG+  +  VAN  D++                   
Sbjct: 369 KQPTLPLIRLRLLYTDESCMFNAIRFGEMLSTRVANVQDVVQFSKVVKRTKTEAVNLDKE 428

Query: 414 GDMTGVAAE-AADVESLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFD 472
                + A+ A  VE L+  Y+E    +K L +   + + +       + + D       
Sbjct: 429 ALRRALEADNATRVEELVDRYFEEAKSNKPLKLFHSKALAEMTYRLLEQRDADAAENIVK 488

Query: 473 AHKRRCIAALLESTAETEKEIAEQLE 498
            +K + +  L+E+    E  I E+LE
Sbjct: 489 FYKEKAVDHLMEAMPNDE-NIDEELE 513


>AE014134-2061|AAF53093.1|  620|Drosophila melanogaster CG16928-PA
           protein.
          Length = 620

 Score =  449 bits (1106), Expect = e-126
 Identities = 235/506 (46%), Positives = 320/506 (63%), Gaps = 23/506 (4%)

Query: 12  DDTLRILIASDIHLGFMENDPVRGEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQAKPSV 71
           D+ +RIL+A+D HLG+ E D VRGEDSF AFEE+L LAV  DVD+ILLGGDLF  A PS 
Sbjct: 12  DNVIRILVATDNHLGYGEKDAVRGEDSFTAFEEILELAVSEDVDMILLGGDLFHDAVPSQ 71

Query: 72  NCMFKCTEIIRKYCLGDKPVSIELLSDQIKNF----SRTVNYEDPNLNISYPILSIHGNH 127
           N + KC E++R+Y  GD+PVS+E+LSDQ + F    +++VNYEDPNLNI+ P+ SIHGNH
Sbjct: 72  NALHKCIELLRRYTFGDRPVSLEILSDQGQCFHNAVNQSVNYEDPNLNIAIPVFSIHGNH 131

Query: 128 DDPVGQGSVSSLDILSITGLVNYFGKWTDYTHVRISPVLLQKGLTRLALYGLSHLKDQRL 187
           DDP G G +SSLD+LS +GLVNYFG+WTD T V ISPVL++KG ++LALYGLSH+ D RL
Sbjct: 132 DDPSGFGRLSSLDLLSTSGLVNYFGRWTDLTQVEISPVLMRKGESQLALYGLSHIHDGRL 191

Query: 188 SRLFAEKKVEMERPD------------ETLDWFNLFVLHQNHADRGHSNYIPEGVLPNFL 235
           +RL  + KV+   P+            E  DWF+L V+HQN ADRG  NY+PE +LP+FL
Sbjct: 192 ARLIKDFKVKFNCPENVANGEDGNESKEEEDWFHLLVVHQNRADRGPKNYLPEDLLPSFL 251

Query: 236 DLVVWGHEHDSHICPMKGNKTEKDSFFVVQPGSTVATSLAAGEALPKHCGLLEIHKGNFK 295
            LV+WGHEHD   C ++  +  K  F+V QPGS+V TSL+ GEA  KH GLLEI+KG FK
Sbjct: 252 HLVIWGHEHD---CRIEPEENAKKRFYVSQPGSSVPTSLSEGEAKKKHVGLLEIYKGKFK 308

Query: 296 LTPLPLQTVRPFIFKTIVLSE--ENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTADL 353
           L PLPL+TVRPF+++++VL++  + +G  + + + KV +F + RV   I+ A    T   
Sbjct: 309 LKPLPLETVRPFVYESVVLADHADELGLVEGDASTKVFKFAQERVEAMIERAVAQHTGHP 368

Query: 354 RQPLLPLIRLSIFYERESQNFNRIRFGQNFNGLVANPNDLLIMXXXXXXXXXXXXXXXXX 413
           +QP LPLIRL + Y  ES  FN IRFG+  +  VAN  D++                   
Sbjct: 369 KQPTLPLIRLRLLYTDESCMFNAIRFGEMLSTRVANVQDVVQFSKVVKRTKTEAVNLDKE 428

Query: 414 GDMTGVAAE-AADVESLLRAYYEAQPKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFD 472
                + A+ A  VE L+  Y+E    +K L +   + + +       + + D       
Sbjct: 429 ALRRALEADNATRVEELVDRYFEEAKSNKPLKLFHSKALAEMTYRLLEQRDADAAENIVK 488

Query: 473 AHKRRCIAALLESTAETEKEIAEQLE 498
            +K + +  L+E+    E  I E+LE
Sbjct: 489 FYKEKAVDHLMEAMPNDE-NIDEELE 513


>AE014297-1413|AAF54724.2|  573|Drosophila melanogaster CG12213-PA,
           isoform A protein.
          Length = 573

 Score = 32.7 bits (71), Expect = 1.6
 Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 414 GDMTGVAAEAADVESLLRAYYEAQ-PKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFD 472
           G +     +  D E  L+  ++AQ  K K L +    +  + V+    KH ED    AFD
Sbjct: 82  GQLAEALQKQHDTEHALQEKFDAQVEKYKLLEIKYTNLEAEFVKS-KKKHIEDT--NAFD 138

Query: 473 AHKRRCIAALLESTAETEKEIAEQLEVCKRELDEADDEKLHTL 515
              ++ +A L +  A  E+E+A   E   + L    + K+H L
Sbjct: 139 QKLQKVLADLHKDKASKEREVAAWKEKLDK-LQRDGEHKIHAL 180


>AE014297-1412|AAN13537.1|  506|Drosophila melanogaster CG12213-PB,
           isoform B protein.
          Length = 506

 Score = 32.7 bits (71), Expect = 1.6
 Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 5/103 (4%)

Query: 414 GDMTGVAAEAADVESLLRAYYEAQ-PKDKRLSVLSVRVITDAVRDFTLKHNEDVLRRAFD 472
           G +     +  D E  L+  ++AQ  K K L +    +  + V+    KH ED    AFD
Sbjct: 82  GQLAEALQKQHDTEHALQEKFDAQVEKYKLLEIKYTNLEAEFVKS-KKKHIEDT--NAFD 138

Query: 473 AHKRRCIAALLESTAETEKEIAEQLEVCKRELDEADDEKLHTL 515
              ++ +A L +  A  E+E+A   E   + L    + K+H L
Sbjct: 139 QKLQKVLADLHKDKASKEREVAAWKEKLDK-LQRDGEHKIHAL 180


>X53992-1|CAA37939.1| 1645|Drosophila melanogaster betaH spectrin
            protein.
          Length = 1645

 Score = 31.5 bits (68), Expect = 3.6
 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 4/79 (5%)

Query: 299  LPLQTVRPFIFKTIVLSEENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTADLRQPLL 358
            +P++ ++P       L +    ++ +NEN    E  + R+N+  DE  ++  A  R  LL
Sbjct: 930  VPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEM--AQKRHALL 987

Query: 359  -PLIRLSIFYERESQNFNR 376
               I L  FY RE  +F +
Sbjct: 988  EDSIHLFGFY-RECDDFEK 1005


>BT011336-1|AAR96128.1|  914|Drosophila melanogaster SD02170p
           protein.
          Length = 914

 Score = 31.5 bits (68), Expect = 3.6
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 4/91 (4%)

Query: 295 KLTPLPLQTVRPFIFKTIVLSEENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTAD-L 353
           KLT LPL+     I   +   +EN  +++    +KV EFLK R      +  +++T D +
Sbjct: 466 KLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLK-REGLYSPQMKEIRTDDPI 524

Query: 354 RQPLLP--LIRLSIFYERESQNFNRIRFGQN 382
              L+   L   S++  R S N + IR G +
Sbjct: 525 ATDLIGALLTGPSVYSSRRSSNDSIIRTGSS 555


>BT001607-1|AAN71362.1|  604|Drosophila melanogaster RE31467p
           protein.
          Length = 604

 Score = 31.5 bits (68), Expect = 3.6
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 4/91 (4%)

Query: 295 KLTPLPLQTVRPFIFKTIVLSEENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTAD-L 353
           KLT LPL+     I   +   +EN  +++    +KV EFLK R      +  +++T D +
Sbjct: 456 KLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLK-REGLYSPQMKEIRTDDPI 514

Query: 354 RQPLLP--LIRLSIFYERESQNFNRIRFGQN 382
              L+   L   S++  R S N + IR G +
Sbjct: 515 ATDLIGALLTGPSVYSSRRSSNDSIIRTGSS 545


>AE014296-651|AAF47766.1| 4097|Drosophila melanogaster CG12008-PA,
           isoform A protein.
          Length = 4097

 Score = 31.5 bits (68), Expect = 3.6
 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 4/79 (5%)

Query: 299 LPLQTVRPFIFKTIVLSEENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTADLRQPLL 358
           +P++ ++P       L +    ++ +NEN    E  + R+N+  DE  ++  A  R  LL
Sbjct: 917 VPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEM--AQKRHALL 974

Query: 359 -PLIRLSIFYERESQNFNR 376
              I L  FY RE  +F +
Sbjct: 975 EDSIHLFGFY-RECDDFEK 992


>AE014296-650|AAS64958.1| 4118|Drosophila melanogaster CG12008-PB,
           isoform B protein.
          Length = 4118

 Score = 31.5 bits (68), Expect = 3.6
 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 4/79 (5%)

Query: 299 LPLQTVRPFIFKTIVLSEENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTADLRQPLL 358
           +P++ ++P       L +    ++ +NEN    E  + R+N+  DE  ++  A  R  LL
Sbjct: 917 VPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEM--AQKRHALL 974

Query: 359 -PLIRLSIFYERESQNFNR 376
              I L  FY RE  +F +
Sbjct: 975 EDSIHLFGFY-RECDDFEK 992


>AE014296-649|AAS64957.1| 4207|Drosophila melanogaster CG12008-PC,
           isoform C protein.
          Length = 4207

 Score = 31.5 bits (68), Expect = 3.6
 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 4/79 (5%)

Query: 299 LPLQTVRPFIFKTIVLSEENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTADLRQPLL 358
           +P++ ++P       L +    ++ +NEN    E  + R+N+  DE  ++  A  R  LL
Sbjct: 917 VPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEM--AQKRHALL 974

Query: 359 -PLIRLSIFYERESQNFNR 376
              I L  FY RE  +F +
Sbjct: 975 EDSIHLFGFY-RECDDFEK 992


>AE013599-3654|AAM68265.1|  904|Drosophila melanogaster CG5411-PB,
           isoform B protein.
          Length = 904

 Score = 31.5 bits (68), Expect = 3.6
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 4/91 (4%)

Query: 295 KLTPLPLQTVRPFIFKTIVLSEENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTAD-L 353
           KLT LPL+     I   +   +EN  +++    +KV EFLK R      +  +++T D +
Sbjct: 456 KLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLK-REGLYSPQMKEIRTDDPI 514

Query: 354 RQPLLP--LIRLSIFYERESQNFNRIRFGQN 382
              L+   L   S++  R S N + IR G +
Sbjct: 515 ATDLIGALLTGPSVYSSRRSSNDSIIRTGSS 545


>AE013599-3653|AAM68264.1|  805|Drosophila melanogaster CG5411-PD,
           isoform D protein.
          Length = 805

 Score = 31.5 bits (68), Expect = 3.6
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 4/91 (4%)

Query: 295 KLTPLPLQTVRPFIFKTIVLSEENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTAD-L 353
           KLT LPL+     I   +   +EN  +++    +KV EFLK R      +  +++T D +
Sbjct: 357 KLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLK-REGLYSPQMKEIRTDDPI 415

Query: 354 RQPLLP--LIRLSIFYERESQNFNRIRFGQN 382
              L+   L   S++  R S N + IR G +
Sbjct: 416 ATDLIGALLTGPSVYSSRRSSNDSIIRTGSS 446


>AE013599-3651|AAM68263.1|  914|Drosophila melanogaster CG5411-PA,
           isoform A protein.
          Length = 914

 Score = 31.5 bits (68), Expect = 3.6
 Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 4/91 (4%)

Query: 295 KLTPLPLQTVRPFIFKTIVLSEENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTAD-L 353
           KLT LPL+     I   +   +EN  +++    +KV EFLK R      +  +++T D +
Sbjct: 466 KLTSLPLEAPITKIINLLSQVQENCSADEARLIDKVLEFLK-REGLYSPQMKEIRTDDPI 524

Query: 354 RQPLLP--LIRLSIFYERESQNFNRIRFGQN 382
              L+   L   S++  R S N + IR G +
Sbjct: 525 ATDLIGALLTGPSVYSSRRSSNDSIIRTGSS 555


>AM294540-1|CAL26523.1|  431|Drosophila melanogaster CG3975 protein.
          Length = 431

 Score = 30.7 bits (66), Expect = 6.3
 Identities = 24/111 (21%), Positives = 48/111 (43%), Gaps = 3/111 (2%)

Query: 245 DSHICPMKGNKTEKDSFFVVQPGSTVATSLAAGEALPKHCGLLEIHKGNFKLTPLPLQTV 304
           D    P K      D+FF  QP     +   +G+   K        + + K +P P  T 
Sbjct: 225 DVKATPSKSTSGTMDNFFKKQPAGAKKSPPESGDKSKKDASNSNKKEASKKKSPSP--TK 282

Query: 305 RPFIFKTIVLSEENIGSEDVNENEKVQEFLKNRVNEAIDEASKLKTADLRQ 355
           +P    T +   +   +E  +E EK+ + L+ +V E+ +++ + K +  ++
Sbjct: 283 KPTTANTSMQLFDEESAESSDEEEKL-DMLRRKVIESDNDSDQEKASSSKR 332


>AF201919-1|AAF71697.1|   97|Drosophila melanogaster CRC-D
          protein.
          Length = 97

 Score = 30.7 bits (66), Expect = 6.3
 Identities = 14/44 (31%), Positives = 25/44 (56%)

Query: 35 GEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQAKPSVNCMFKCT 78
          G+D  +  EEV SL +  D ++++   DL D+ +  + C+  CT
Sbjct: 54 GDDEALTLEEVASLQLLSDEEMVVEIFDLKDEGRYILVCLLFCT 97


>AE014134-3388|ABC65922.1|  105|Drosophila melanogaster CG8669-PD,
           isoform D protein.
          Length = 105

 Score = 30.7 bits (66), Expect = 6.3
 Identities = 14/44 (31%), Positives = 25/44 (56%)

Query: 35  GEDSFIAFEEVLSLAVQCDVDLILLGGDLFDQAKPSVNCMFKCT 78
           G+D  +  EEV SL +  D ++++   DL D+ +  + C+  CT
Sbjct: 62  GDDEALTLEEVASLQLLSDEEMVVEIFDLKDEGRYILVCLLFCT 105


  Database: fruitfly
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 24,830,863
  Number of sequences in database:  52,641
  
Lambda     K      H
   0.318    0.135    0.391 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 27,811,708
Number of Sequences: 52641
Number of extensions: 1136538
Number of successful extensions: 3158
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3146
Number of HSP's gapped (non-prelim): 16
length of query: 628
length of database: 24,830,863
effective HSP length: 89
effective length of query: 539
effective length of database: 20,145,814
effective search space: 10858593746
effective search space used: 10858593746
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 65 (30.3 bits)

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