BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001068-TA|BGIBMGA001068-PA|IPR002529|Fumarylacetoacetate (FAA) hydrolase (285 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A... 364 1e-99 UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to fumarylace... 247 2e-64 UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase domain-co... 245 9e-64 UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105 pr... 237 3e-61 UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p ... 237 3e-61 UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B... 224 2e-57 UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 220 4e-56 UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 216 6e-55 UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1; ... 215 1e-54 UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 213 4e-54 UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 207 3e-52 UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 206 5e-52 UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 202 6e-51 UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 197 3e-49 UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 195 1e-48 UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 194 2e-48 UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 194 3e-48 UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 188 1e-46 UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 188 2e-46 UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 187 3e-46 UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 186 4e-46 UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 185 1e-45 UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 183 4e-45 UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 183 5e-45 UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 182 9e-45 UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family pr... 180 4e-44 UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 177 2e-43 UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family pr... 177 2e-43 UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 177 3e-43 UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 176 5e-43 UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17; S... 176 5e-43 UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 175 8e-43 UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1; ... 175 8e-43 UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 175 1e-42 UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family pr... 174 2e-42 UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre... 174 2e-42 UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family pr... 173 6e-42 UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 172 7e-42 UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 172 7e-42 UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4; Eu... 171 1e-41 UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase;... 171 2e-41 UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family pr... 170 3e-41 UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctiona... 169 5e-41 UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 169 5e-41 UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Re... 169 7e-41 UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase ... 169 7e-41 UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 169 7e-41 UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 168 1e-40 UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 167 2e-40 UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 167 3e-40 UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 167 4e-40 UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 167 4e-40 UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 166 5e-40 UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp... 166 5e-40 UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila melanogaste... 166 6e-40 UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 165 9e-40 UniRef50_O53242 Cluster: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-D... 165 1e-39 UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase;... 165 1e-39 UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 165 1e-39 UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 164 2e-39 UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4; Th... 164 2e-39 UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep: B... 164 3e-39 UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family pr... 162 8e-39 UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase... 162 1e-38 UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3; Burkholderiale... 161 1e-38 UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1; ... 161 1e-38 UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2; ... 161 2e-38 UniRef50_Q67K64 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d... 161 2e-38 UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium di... 161 2e-38 UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 160 3e-38 UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 159 6e-38 UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep... 159 7e-38 UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 159 1e-37 UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 158 1e-37 UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus ter... 158 1e-37 UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 158 2e-37 UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 157 2e-37 UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 157 4e-37 UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 156 5e-37 UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 156 5e-37 UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1; ... 155 9e-37 UniRef50_Q88Y59 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioateisom... 155 2e-36 UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia farci... 155 2e-36 UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 154 3e-36 UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 153 4e-36 UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1, 7... 153 4e-36 UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 153 4e-36 UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 152 9e-36 UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep: Lm... 152 1e-35 UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 151 2e-35 UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 151 3e-35 UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358; ... 150 3e-35 UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family pr... 150 3e-35 UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family pr... 150 5e-35 UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase... 150 5e-35 UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4; Pezizomy... 149 6e-35 UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 149 1e-34 UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3; c... 148 2e-34 UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 146 4e-34 UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584... 146 6e-34 UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 146 6e-34 UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 146 7e-34 UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 145 1e-33 UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 145 1e-33 UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 144 2e-33 UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family pr... 144 2e-33 UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 144 2e-33 UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9;... 144 2e-33 UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 144 3e-33 UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein; ... 144 3e-33 UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 143 4e-33 UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 143 5e-33 UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA) hydr... 142 7e-33 UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1; F... 142 7e-33 UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 141 2e-32 UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 141 2e-32 UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom... 141 2e-32 UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1;... 141 2e-32 UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 140 4e-32 UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1; ... 140 5e-32 UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation bifu... 139 6e-32 UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 139 9e-32 UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family pr... 139 9e-32 UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISO... 138 1e-31 UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 137 3e-31 UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase;... 137 3e-31 UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 137 3e-31 UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family pr... 137 3e-31 UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 137 3e-31 UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 136 6e-31 UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 136 6e-31 UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_030014... 135 1e-30 UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 135 1e-30 UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 135 1e-30 UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate i... 134 2e-30 UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 133 4e-30 UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 133 4e-30 UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 132 7e-30 UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family pr... 132 7e-30 UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family pr... 132 1e-29 UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 132 1e-29 UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD - P... 131 2e-29 UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 131 2e-29 UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF; ... 131 2e-29 UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6;... 131 2e-29 UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2; Proteobacteria... 130 3e-29 UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate iso... 130 3e-29 UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 130 4e-29 UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family pr... 130 4e-29 UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 130 4e-29 UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albic... 129 7e-29 UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 129 7e-29 UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 128 1e-28 UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6; Pezizomy... 128 2e-28 UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate hydratase... 128 2e-28 UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 127 3e-28 UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4; Actinomy... 126 5e-28 UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14; ... 126 8e-28 UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3; E... 126 8e-28 UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 125 1e-27 UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5; E... 125 1e-27 UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM - P... 125 1e-27 UniRef50_Q4JXJ3 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d... 124 3e-27 UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase... 124 3e-27 UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6; Asc... 123 5e-27 UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation bifu... 122 1e-26 UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 122 1e-26 UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albic... 121 2e-26 UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 120 3e-26 UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41; Gam... 119 7e-26 UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1; ... 118 2e-25 UniRef50_Q2S2N6 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d... 118 2e-25 UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 118 2e-25 UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid... 118 2e-25 UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 117 3e-25 UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 116 5e-25 UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1; ... 116 7e-25 UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3;... 115 2e-24 UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 114 2e-24 UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase domain-co... 114 2e-24 UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 113 4e-24 UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family pr... 113 6e-24 UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 112 8e-24 UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 112 1e-23 UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep... 111 1e-23 UniRef50_Q8G4X7 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d... 111 2e-23 UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 111 3e-23 UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 110 3e-23 UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta... 110 5e-23 UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 110 5e-23 UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2; ... 110 5e-23 UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 109 1e-22 UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 109 1e-22 UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella per... 108 2e-22 UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate hydratase/2-oxohept... 108 2e-22 UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1; ... 107 2e-22 UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4; ... 107 3e-22 UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep:... 106 6e-22 UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 106 7e-22 UniRef50_A1HJ09 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 106 7e-22 UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep... 105 1e-21 UniRef50_Q3INL8 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d... 104 3e-21 UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 103 4e-21 UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 103 4e-21 UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family pr... 103 4e-21 UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium ja... 103 7e-21 UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=... 103 7e-21 UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP020... 102 9e-21 UniRef50_UPI00006CDD7C Cluster: fumarylacetoacetate hydrolase fa... 101 2e-20 UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family pr... 101 2e-20 UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 101 2e-20 UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation; 2-h... 100 4e-20 UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1; ... 100 4e-20 UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 100 5e-20 UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family pr... 100 8e-20 UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19 UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 98 3e-19 UniRef50_Q9X4X0 Cluster: DitH; n=8; Proteobacteria|Rep: DitH - P... 97 3e-19 UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep:... 97 3e-19 UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 97 6e-19 UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|R... 95 2e-18 UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 95 2e-18 UniRef50_A6E756 Cluster: Fumarylacetoacetate hydrolase family pr... 94 3e-18 UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family pr... 93 6e-18 UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1; ... 93 6e-18 UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre... 93 7e-18 UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 93 7e-18 UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7;... 93 7e-18 UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 93 1e-17 UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 91 2e-17 UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 91 2e-17 UniRef50_Q22Y44 Cluster: Fumarylacetoacetate hydrolase family pr... 91 2e-17 UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family pr... 90 5e-17 UniRef50_Q5KVH0 Cluster: Hypothetical conserved protein; n=2; Ge... 90 7e-17 UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7; Prot... 89 9e-17 UniRef50_A3PZU8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 89 1e-16 UniRef50_A0GBX8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 89 1e-16 UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep:... 89 2e-16 UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 88 2e-16 UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 88 3e-16 UniRef50_A6D592 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 88 3e-16 UniRef50_A5V6I4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 88 3e-16 UniRef50_Q5UY90 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom... 88 3e-16 UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8; Xan... 87 4e-16 UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family pr... 87 4e-16 UniRef50_A4EDA6 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d... 87 5e-16 UniRef50_A0UKA6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 87 6e-16 UniRef50_A0QDN9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 86 8e-16 UniRef50_Q1VYL9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 86 1e-15 UniRef50_A2U2G0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 85 1e-15 UniRef50_A5VDV9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 85 2e-15 UniRef50_A5V0Z8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 85 2e-15 UniRef50_Q97UR1 Cluster: 2-hydroxyhepta-2 ,4-diene-1,7-dioate is... 85 2e-15 UniRef50_Q2BPV1 Cluster: Putative uncharacterized protein; n=4; ... 85 3e-15 UniRef50_A4CE53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 85 3e-15 UniRef50_Q88M65 Cluster: Fumarylacetoacetate hydrolase family pr... 83 6e-15 UniRef50_Q72P81 Cluster: Fumarylacetoacetate hydrolase family pr... 83 6e-15 UniRef50_A4SV99 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 83 6e-15 UniRef50_A0QS23 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 82 1e-14 UniRef50_Q15XL1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 81 2e-14 UniRef50_Q5P741 Cluster: Fumarylpyruvate hydrolase; n=14; Proteo... 81 4e-14 UniRef50_O86346 Cluster: POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXY... 80 7e-14 UniRef50_Q7NUB2 Cluster: Probable isomerase; n=3; Betaproteobact... 77 4e-13 UniRef50_Q1QDY9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 77 4e-13 UniRef50_A2CBF2 Cluster: Putative uncharacterized protein; n=1; ... 77 4e-13 UniRef50_A1UG87 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 77 4e-13 UniRef50_Q89FA1 Cluster: Bll6800 protein; n=3; Proteobacteria|Re... 77 7e-13 UniRef50_Q97VT9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso... 76 9e-13 UniRef50_Q0LGD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 76 1e-12 UniRef50_A4F0I3 Cluster: Fumarylacetoacetate hydrolase family pr... 74 5e-12 UniRef50_Q7WPF0 Cluster: Putative fumarylacetoacetate hydrolase ... 73 6e-12 UniRef50_Q0S954 Cluster: Possible hydratase; n=3; Actinomycetale... 73 6e-12 UniRef50_A4YZ43 Cluster: Putative Fumarylacetoacetate hydrolase ... 73 1e-11 UniRef50_Q4AQ85 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 72 1e-11 UniRef50_Q4WH18 Cluster: Fumarylacetoacetate hydrolase family pr... 72 1e-11 UniRef50_Q2W964 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 72 2e-11 UniRef50_A3SNB2 Cluster: Fumarylacetoacetate hydrolase family pr... 71 3e-11 UniRef50_A4QX03 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11 UniRef50_Q18X79 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 71 3e-11 UniRef50_Q3WGU5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 69 2e-10 UniRef50_Q02AF6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 69 2e-10 UniRef50_Q4D6U8 Cluster: Putative uncharacterized protein; n=2; ... 69 2e-10 UniRef50_Q7MXX3 Cluster: Fumarylacetoacetate hydrolase family pr... 67 4e-10 UniRef50_Q395G4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta... 67 4e-10 UniRef50_Q6F7V5 Cluster: Putative uncharacterized protein; n=2; ... 66 7e-10 UniRef50_Q0SB97 Cluster: Possible fumarylacetoacetate hydrolase ... 66 7e-10 UniRef50_Q4J6K3 Cluster: 4-hydroxyphenylacetate degradation bifu... 66 7e-10 UniRef50_Q3II31 Cluster: Putative fumarylacetoacetate hydrolase ... 66 1e-09 UniRef50_Q4J7I6 Cluster: Conserved protein; n=3; Thermoprotei|Re... 66 1e-09 UniRef50_Q0AN49 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 65 2e-09 UniRef50_Q6KZ97 Cluster: Fumarylacetoacetase; n=2; Thermoplasmat... 65 2e-09 UniRef50_Q6MNK0 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09 UniRef50_Q8D6F8 Cluster: 2-keto-4-pentenoate hydratase; n=22; Pr... 62 2e-08 UniRef50_A7K1Y8 Cluster: Fumarylacetoacetate hydrolase family pr... 62 2e-08 UniRef50_Q3E159 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 61 4e-08 UniRef50_Q9CKS8 Cluster: HpaG; n=1; Pasteurella multocida|Rep: H... 60 5e-08 UniRef50_Q60C48 Cluster: Fumarylacetoacetate hydrolase family pr... 60 5e-08 UniRef50_Q8KDK4 Cluster: Fumarylacetoacetate hydrolase family pr... 60 8e-08 UniRef50_Q7UMG2 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d... 60 8e-08 UniRef50_Q5KYI4 Cluster: Hypothetical conserved protein; n=3; Ba... 60 8e-08 UniRef50_A0VBW0 Cluster: 4-hydroxyphenylacetate degradation bifu... 60 8e-08 UniRef50_Q4FWM5 Cluster: Putative uncharacterized protein; n=3; ... 59 1e-07 UniRef50_Q5B6D4 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07 UniRef50_A7D1J1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 59 1e-07 UniRef50_A1TDQ7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 59 1e-07 UniRef50_A5EF32 Cluster: Putative Fumarylacetoacetate (FAA) hydr... 58 2e-07 UniRef50_Q44SK1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 57 4e-07 UniRef50_A5VED2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de... 57 6e-07 UniRef50_A3VRL8 Cluster: Putative isomerase-decarboxylase-like p... 56 1e-06 UniRef50_A0SP98 Cluster: Fumarylacetoacetate hydrolase family pr... 54 5e-06 UniRef50_A3IA41 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 53 1e-05 UniRef50_A7QL05 Cluster: Chromosome undetermined scaffold_116, w... 52 1e-05 UniRef50_A1SUQ4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 52 2e-05 UniRef50_Q9KDZ0 Cluster: BH1071 protein; n=2; Bacillus|Rep: BH10... 52 2e-05 UniRef50_Q5V2I1 Cluster: Fumarylacetoacetate hydrolase family pr... 50 5e-05 UniRef50_Q1GRD3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 50 7e-05 UniRef50_A6Q9W9 Cluster: Fumarylacetoacetate hydrolase; n=1; Sul... 50 7e-05 UniRef50_Q5DHL1 Cluster: SJCHGC00506 protein; n=2; Schistosoma j... 49 1e-04 UniRef50_A6C0W6 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d... 48 2e-04 UniRef50_A3VNC8 Cluster: Possible isomerase/decarboxylase; n=1; ... 48 3e-04 UniRef50_Q0HT13 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=... 48 4e-04 UniRef50_Q2UV71 Cluster: Predicted protein; n=1; Aspergillus ory... 46 8e-04 UniRef50_A2UC21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept... 42 0.018 UniRef50_A6Q508 Cluster: Fumarylacetoacetate hydrolase family pr... 41 0.031 UniRef50_Q1IPR5 Cluster: Fe-S protein, radical SAM family; n=5; ... 40 0.096 UniRef50_A7Q3E6 Cluster: Chromosome chr13 scaffold_48, whole gen... 39 0.17 UniRef50_Q4RJI4 Cluster: Chromosome 3 SCAF15037, whole genome sh... 38 0.39 UniRef50_Q10JF6 Cluster: Isomerase, putative; n=10; Magnoliophyt... 36 1.6 UniRef50_Q6FUW3 Cluster: Similarities with sp|P08640 Saccharomyc... 36 1.6 UniRef50_Q5B250 Cluster: Putative uncharacterized protein; n=1; ... 36 1.6 UniRef50_Q4X003 Cluster: Alpha-L-arabinofuranosidase A; n=7; Pez... 36 1.6 UniRef50_Q600A8 Cluster: Glucose-6-phosphate isomerase; n=3; Myc... 35 2.7 UniRef50_Q6YRJ1 Cluster: Putative uncharacterized protein; n=1; ... 34 4.8 UniRef50_Q0TRU3 Cluster: Putative permease; n=1; Clostridium per... 34 4.8 UniRef50_Q22GI1 Cluster: Putative uncharacterized protein; n=1; ... 33 6.3 UniRef50_Q245B0 Cluster: Putative uncharacterized protein; n=1; ... 33 8.3 >UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A; n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase isoform A - Bombyx mori (Silk moth) Length = 330 Score = 364 bits (896), Expect = 1e-99 Identities = 161/288 (55%), Positives = 216/288 (75%), Gaps = 3/288 (1%) Query: 1 MKLLQFSYKNSD-GIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXX 59 MKL+QFSYK+S IR G+L+GD++VDINK D LP+TL+++L+ Sbjct: 43 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 102 Query: 60 X--LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKL 117 LS +TL AP+HG DK+LC+GLNYKDHC+EQ LTPP +P +F+KF ST++GP+ +++ Sbjct: 103 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 162 Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177 + DV+K V E+EL VV+G++AS V A +V GYT+AQDI A DW+K K + Q LLG Sbjct: 163 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 222 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 K+MDTFCP+GP ++TSDE+G L V CS+NGV KQ S+T Q +H IP ++ R+S+VMT Sbjct: 223 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 282 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285 L+PGD+ILTGTPGGVG+YR PPE+LQPGDV+TSEIE IG F+ R+E+F Sbjct: 283 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 330 >UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to fumarylacetoacetate hydrolase domain containing 2A isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to fumarylacetoacetate hydrolase domain containing 2A isoform 2 - Apis mellifera Length = 334 Score = 247 bits (605), Expect = 2e-64 Identities = 127/289 (43%), Positives = 179/289 (61%), Gaps = 8/289 (2%) Query: 1 MKLLQFSYKNSDGIRAG--FLDGDNVVDINKEDPKLPSTLIELLK--TNXXXXXXXXXXX 56 M+ +QF+ KN G + G +++ ++ D ++P+TL + L+ + Sbjct: 46 MRFVQFTGKNGGPQHLGVQLVQGGDIIAVSAVDSRIPNTLKKFLEGGDDLLKKAKRIVAE 105 Query: 57 XXXXLSGITLK--APVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT 114 + + + APV DK+ CVGLNY HC+EQ ++PPE P IF+KF S ++GP D Sbjct: 106 GRSVIPEVEVNFLAPVTRMDKLACVGLNYIGHCKEQGVSPPESPVIFSKFASNIIGPRDN 165 Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS-Q 173 I L +S V E EL +VIGKK ++++ DY+ GYTIAQDI A DW+K+K+ Q Sbjct: 166 IMLP-PISDKVDWEAELAIVIGKKCKALNNNEGEDYIFGYTIAQDITARDWQKSKRNGGQ 224 Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233 LLGKAMDTFCP+GP +VT + I + NL VK +NG KQ NT++ I K +I+A +S Sbjct: 225 FLLGKAMDTFCPLGPAVVTKEAISDINNLTVKTWVNGNIKQDGNTSELIFKPHEIVAYIS 284 Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 MTLLPGD+ILTGTP GVG R PPE+LQ GDV+ +EI+ +G +V Sbjct: 285 QFMTLLPGDVILTGTPSGVGFTRKPPEYLQRGDVLETEIQGLGRLRNKV 333 >UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase domain-containing protein 2B; n=41; cellular organisms|Rep: Fumarylacetoacetate hydrolase domain-containing protein 2B - Homo sapiens (Human) Length = 314 Score = 245 bits (600), Expect = 9e-64 Identities = 123/288 (42%), Positives = 169/288 (58%), Gaps = 7/288 (2%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDN--VVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXX 58 M+L+QF + G G G+ V+++N DP LP T+ + L+ Sbjct: 27 MRLVQFRAPHLVGPHLGLETGNGGGVINLNAFDPTLPKTMTQFLEQGEATLSVARRALAA 86 Query: 59 XX----LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT 114 S +T APV DKV+CVG+NY DHC+EQ + P+ P IF+KF S++VGP D Sbjct: 87 QLPVLPWSEVTFLAPVTWPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPYDE 146 Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174 + L S+ V E+EL VVIGKK + ++ A +V G+T+A D+ A DW + Q Sbjct: 147 VVLPPQ-SQEVDWEVELAVVIGKKGKHIKATDAMAHVAGFTVAHDVSARDWLTRRNGKQW 205 Query: 175 LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSN 234 LLGK DTFCP+GP +VT D + +P NL + C +NG Q SNTNQ + K D+IA +S Sbjct: 206 LLGKTFDTFCPLGPALVTKDSVADPHNLKICCRVNGEVVQSSNTNQMVFKTEDLIAWVSQ 265 Query: 235 VMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 +T PGD+ILTGTP GVGV+R PP FL+ GD + EIE +G +V Sbjct: 266 FVTFYPGDVILTGTPPGVGVFRKPPVFLKKGDEVQCEIEELGVIINKV 313 >UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105 protein; n=2; Gallus gallus|Rep: PREDICTED: similar to CGI-105 protein - Gallus gallus Length = 406 Score = 237 bits (579), Expect = 3e-61 Identities = 106/221 (47%), Positives = 149/221 (67%), Gaps = 1/221 (0%) Query: 62 SGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV 121 +G+ L AP+ +KV+CVGLNY+DHC EQ + P+ P IF+KFPS + GP D I + Sbjct: 186 AGVRLLAPIDDPEKVICVGLNYRDHCLEQDVKVPKEPLIFSKFPSAIAGPFDDIVHPAES 245 Query: 122 SKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMD 181 S+ V E+EL +IGK + S A ++++G+T+A D+ A DW+ + Q LLGK D Sbjct: 246 SE-VDWEVELAAIIGKTGRHIQESVAMEHIVGFTVANDVSARDWQMRRNGRQWLLGKTFD 304 Query: 182 TFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241 TFCPIGP IVT D + + NL ++CS+NG Q S+TNQ I ++P ++A +S +TL PG Sbjct: 305 TFCPIGPAIVTKDSVTDVHNLRIRCSVNGQLMQSSSTNQLIFRLPQLVAWVSQFVTLRPG 364 Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 D++LTGTP GVGV+R PP FL+PGD + EIE +GT +V Sbjct: 365 DVLLTGTPPGVGVFRKPPMFLKPGDEVQCEIEELGTICNKV 405 >UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p - Drosophila melanogaster (Fruit fly) Length = 293 Score = 237 bits (579), Expect = 3e-61 Identities = 108/213 (50%), Positives = 145/213 (68%), Gaps = 1/213 (0%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 +TL P+ K++C+GLNY+DHC+EQ P+ P F+KF + +VGP D + + S Sbjct: 73 VTLLPPLTDPGKIICIGLNYQDHCDEQNKPTPKEPLFFSKFNNALVGPQDNV-IAHAASS 131 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183 + E+EL VIGK A +V S A DYV GY++AQDI A DW+K + Q L+GK+MDTF Sbjct: 132 KIDWEVELVCVIGKVARQVPKSQAMDYVFGYSVAQDISARDWQKERNGGQFLMGKSMDTF 191 Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243 P+GP +V + + NLN+K +NGV+KQ NT I K+ D+I RLS +TLLPGDI Sbjct: 192 LPLGPAVVHKSLVPDVYNLNLKTWVNGVEKQNGNTGNLIFKLDDVINRLSQTITLLPGDI 251 Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 I+TGTP GVG++R PPEFLQPGDV+ SEI +G Sbjct: 252 IVTGTPKGVGMHRTPPEFLQPGDVVQSEIVGLG 284 >UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B; n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase isoform B - Bombyx mori (Silk moth) Length = 360 Score = 224 bits (547), Expect = 2e-57 Identities = 97/158 (61%), Positives = 125/158 (79%) Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187 E+EL VV+G++AS V A +V GYT+AQDI A DW+K K + Q LLGK+MDTFCP+G Sbjct: 203 EVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLG 262 Query: 188 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247 P ++TSDE+G L V CS+NGV KQ S+T Q +H IP ++ R+S+VMTL+PGD+ILTG Sbjct: 263 PCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTG 322 Query: 248 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285 TPGGVG+YR PPE+LQPGDV+TSEIE IG F+ R+E+F Sbjct: 323 TPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 360 Score = 145 bits (352), Expect = 1e-33 Identities = 63/127 (49%), Positives = 91/127 (71%), Gaps = 3/127 (2%) Query: 1 MKLLQFSYKNSD-GIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXX 59 MKL+QFSYK+S IR G+L+GD++VDINK D LP+TL+++L+ Sbjct: 43 MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 102 Query: 60 X--LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKL 117 LS +TL AP+HG DK+LC+GLNYKDHC+EQ LTPP +P +F+KF ST++GP+ +++ Sbjct: 103 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 162 Query: 118 KMDVSKA 124 + DV+K+ Sbjct: 163 RTDVTKS 169 >UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase; n=1; Blastopirellula marina DSM 3645|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase - Blastopirellula marina DSM 3645 Length = 284 Score = 220 bits (537), Expect = 4e-56 Identities = 116/278 (41%), Positives = 155/278 (55%), Gaps = 3/278 (1%) Query: 7 SYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXXL--SGI 64 +Y++ G RA GD+ +D++ D LP+ + LL +G Sbjct: 5 TYQSEAGPRAAVARGDDFIDLHHTDHTLPTDMKSLLALGDVAREKVLAAREHGDPIPAGS 64 Query: 65 TLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 124 + P+ KV+CVGLNY DH +E T + P IFNKFPS ++ +D I L + S+ Sbjct: 65 RILTPIINPQKVICVGLNYADHAKETGATVGDEPVIFNKFPSALIADHDEIHLPPESSQ- 123 Query: 125 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 184 V E EL V IG + A +V GY DI A DW+K K Q LLGK DTF Sbjct: 124 VDYEAELVVAIGTAGKHIPQGEAMSHVGGYCCGNDISARDWQKGKPGKQWLLGKTFDTFA 183 Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244 P+GP + T DEI +P NL ++C +NG Q+S+T+Q I KI +I+ LSNV+ L PGD+I Sbjct: 184 PLGPVLYTPDEIADPNNLAIRCRLNGETMQESSTSQLIFKIDFLISYLSNVVMLQPGDLI 243 Query: 245 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TGTP GVGV R+P FLQPGD + EIE +G RV Sbjct: 244 FTGTPHGVGVARDPQVFLQPGDQVEVEIEGLGLLTNRV 281 >UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=3; cellular organisms|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus halodurans Length = 319 Score = 216 bits (527), Expect = 6e-55 Identities = 102/217 (47%), Positives = 139/217 (64%), Gaps = 3/217 (1%) Query: 67 KAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV 126 +AP+ + K++CVG NY++H E K P+ P IF KF +T++GP D + L +++ + Sbjct: 95 EAPILNSKKIICVGHNYREHILEMKREIPKYPVIFAKFANTIIGPEDNVPLP-SITEQLD 153 Query: 127 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPI 186 E EL VIGKKA V A DYV GYTI DI A D ++ + Q L GK +D P+ Sbjct: 154 YEAELAFVIGKKAKDVAKEDALDYVAGYTIVNDITARDLQR--RTIQWLQGKTLDGSLPM 211 Query: 187 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 246 GPW+VT DEI NP L + S+NG ++Q+SNT + I D++ LS +MTL PGD++ T Sbjct: 212 GPWLVTKDEIPNPHQLEITLSVNGEERQRSNTKNLVFSIQDLVVFLSGIMTLEPGDVVCT 271 Query: 247 GTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 GTPGGVGV R P FLQ GDV+ E+E +GT E RV+ Sbjct: 272 GTPGGVGVAREPQLFLQDGDVVRIELEKVGTLENRVK 308 >UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 305 Score = 215 bits (524), Expect = 1e-54 Identities = 115/284 (40%), Positives = 159/284 (55%), Gaps = 17/284 (5%) Query: 15 RAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX------LSGITLKA 68 R G L ++++D+ D +P+ + L N + +KA Sbjct: 24 RLGALLENSIIDLCSADKSIPNDMRSFLSLNSTDKWSKVINVINNINNRRIPIENCKIKA 83 Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128 P+ K++C+GLNYK+H E K+ P+ P +F+KF + + GPND+I +K S V E Sbjct: 84 PIEPG-KIICIGLNYKEHANEAKMAIPKEPIVFSKFDNAICGPNDSI-IKPVESDEVDYE 141 Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188 +EL VVIGK+A V S A YV GYT+ D+ A DW+ K SQ LLGK DTF PIGP Sbjct: 142 VELVVVIGKQAKNVSESDALQYVAGYTVGNDVSARDWQLRKNNSQWLLGKTFDTFAPIGP 201 Query: 189 WIVTSDEIG--------NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 IV + E+ +P NL++KC++NG Q S T +FI I +++ LS + TL P Sbjct: 202 SIVINPEVAALSDDTYFDPNNLSIKCTLNGQVVQNSTTKEFIFNIQTVVSYLSKLFTLNP 261 Query: 241 GDIILTGTPGGVGVYRNP-PEFLQPGDVITSEIENIGTFETRVE 283 GDII TGTP GVG R P P FL+ GDVI EIE +G+ V+ Sbjct: 262 GDIIFTGTPSGVGFIRKPNPIFLKSGDVIKCEIEELGSLVNNVK 305 >UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Planctomyces maris DSM 8797|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Planctomyces maris DSM 8797 Length = 290 Score = 213 bits (520), Expect = 4e-54 Identities = 118/290 (40%), Positives = 163/290 (56%), Gaps = 10/290 (3%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDNVV---DINKEDPKLPSTLIELLKTNX----XXXXXXX 53 MKL +N + A +D DN + D++ D LP +L +L Sbjct: 1 MKLATIQTENGIQV-ASVIDQDNKLTFFDLSAFDENLPRSLKGILAVEGGLERAKAAAEQ 59 Query: 54 XXXXXXXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND 113 ++G TL AP+ KVLC+GLNY+DH EE + P+ P F+KF S+V G Sbjct: 60 AQQADRQITG-TLLAPIPSPGKVLCIGLNYRDHAEETGMPFPDEPVCFSKFSSSVTGSGQ 118 Query: 114 TIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ 173 I++ V++ V E EL VIGK V ++A DYV GY D+ A DW+ + Q Sbjct: 119 PIRIP-SVAREVDYEAELVAVIGKTCRNVTQANASDYVAGYMNGHDVSARDWQIGRPGGQ 177 Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233 LLGK DTF P GP++VT+DEI N +L++K ++NG Q SNT++FI I ++IA +S Sbjct: 178 WLLGKTADTFAPTGPYLVTADEIKNANSLSIKLTLNGEVLQNSNTDKFIFTIEEVIAFVS 237 Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 ++TL PGDII TGTP GVG+ R PP +LQPGD EI+ +G VE Sbjct: 238 QILTLEPGDIIFTGTPPGVGMARKPPVYLQPGDQACIEIQGLGMLHNTVE 287 >UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Pirellula sp.|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Rhodopirellula baltica Length = 342 Score = 207 bits (505), Expect = 3e-52 Identities = 103/214 (48%), Positives = 131/214 (61%), Gaps = 1/214 (0%) Query: 66 LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125 L PV +K+LC+GLNY DH E P LP +F+KF S +VG I L +S V Sbjct: 123 LLPPVTCPEKILCIGLNYLDHAIETGAEKPSLPVVFSKFNSALVGHGQDIVLPK-ISDKV 181 Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185 E EL VVIGK VD++ A D V GY + D+ + DW+K + Q L+GK+ DTF P Sbjct: 182 DYEAELVVVIGKTVRHVDANEAMDAVFGYAVGHDVSSRDWQKGRPGGQWLVGKSFDTFAP 241 Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 +GP +VT+DEI +P NL ++ ING Q+S T+Q I IP +IA LS MTL PGD+I Sbjct: 242 LGPAVVTADEISDPGNLPIRLHINGETLQESKTDQLIFDIPALIAHLSKFMTLKPGDLIF 301 Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFE 279 TGTP GVG R PP +L PGD EI+ IG E Sbjct: 302 TGTPSGVGDARTPPRYLAPGDRCVVEIDGIGRLE 335 >UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=2; Ectothiorhodospiraceae|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospirahalophila (strain DSM 244 / SL1)) Length = 316 Score = 206 bits (503), Expect = 5e-52 Identities = 101/226 (44%), Positives = 136/226 (60%), Gaps = 9/226 (3%) Query: 64 ITLKAPV-HGNDKVLCVGLNYKDHCEEQK------LTPPELPFIFNKFPSTVVGPNDTIK 116 +T AP+ H V+C+GLNY DH E + L PE P +F K ++V GP D Sbjct: 88 LTFLAPLPHPPRNVICLGLNYADHARESQQAKGDELALPEAPVVFTKATTSVAGPYDDFI 147 Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176 L V+ + E+EL VVIG+ + A +V GYT+ D+ A D + K Q L Sbjct: 148 LDPSVTSELDWEVELAVVIGRGGRHIREQDALQHVFGYTVVNDLSARDLQFRHK--QFFL 205 Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236 GK++D CP+GPWI T++ + NP NL + C IN +Q+S+T + + IP IIA LS VM Sbjct: 206 GKSVDGSCPMGPWITTANAVPNPHNLALSCRINDTTEQQSHTGEMVFSIPRIIAELSRVM 265 Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TL+PGDII TGTP GVG R PP FLQ GD++TSE+E +GT R+ Sbjct: 266 TLIPGDIIATGTPAGVGFARTPPRFLQAGDIVTSEVEGLGTLRNRI 311 >UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 293 Score = 202 bits (494), Expect = 6e-51 Identities = 106/232 (45%), Positives = 137/232 (59%), Gaps = 9/232 (3%) Query: 61 LSGITLKAPV-HGNDKVLCVGLNYKDHCEE-------QKLTPPELPFIFNKFPSTVVGPN 112 L + L AP+ V C+G NY H EE Q PE P F+K +TV+GP+ Sbjct: 58 LDEVRLLAPIPQPRRNVFCMGWNYLTHFEEGRGRREGQGEELPEYPTFFDKPTTTVIGPH 117 Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS 172 D I + S+ + E EL VVIG+ + + A D+V GYT A D+ A D ++ Sbjct: 118 DDIPFDPNFSEKIDYEAELAVVIGRSGRSIPAGEAMDHVFGYTAANDVTARDVQRRHG-G 176 Query: 173 QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 232 Q L GK MD CP+GPWIVT+DEI + QNL V+C +NGVQKQ SNT + + +I L Sbjct: 177 QWLKGKGMDGSCPLGPWIVTADEIPDVQNLQVQCRVNGVQKQNSNTRFMVFPVARLIEEL 236 Query: 233 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 S MTLLPGD++LTGTP GVG R PPEFL+PGD +T +E +G RV E Sbjct: 237 SLAMTLLPGDVLLTGTPEGVGYARTPPEFLRPGDEVTVYVEGVGEISNRVVE 288 >UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Parvibaculum lavamentivorans DS-1 Length = 291 Score = 197 bits (480), Expect = 3e-49 Identities = 109/284 (38%), Positives = 147/284 (51%), Gaps = 7/284 (2%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX 60 MKL FS S +R G + D +VD++K P+LP + L+ Sbjct: 1 MKLATFSEGGS--VRIGVVRDDGIVDLSKAAPELPRDMKSLIGNEAALARAREVAKGGAA 58 Query: 61 L--SGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLK 118 L S + L AP+ KVL +GLNY+DH EE PE FNK + + GP I L Sbjct: 59 LPLSAVKLLAPIPNPGKVLAIGLNYRDHVEESGQPMPEHQVWFNKQHNCITGPYADIALP 118 Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGK 178 VS + E E+ VIGK+ V A + + GY + D+ DW+ Q+ GK Sbjct: 119 -SVSAFLDYEAEMCFVIGKRCKHVPKERAHEVIAGYFVGDDVSVRDWQLRTNTWQI--GK 175 Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTL 238 + DT PIGPWIVT DE+G+P L++KC +NG +Q SNT I D IA L+ TL Sbjct: 176 SFDTHGPIGPWIVTPDEVGDPHALDIKCWVNGELRQNSNTKHLIFDCFDQIAHLTQAFTL 235 Query: 239 LPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GD+I TGT GG+G P + L+ GDV+ E+E +G E RV Sbjct: 236 DIGDVIFTGTSGGIGAAMKPMQLLKEGDVVRVEVEKLGYIENRV 279 >UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Solibacter usitatus Ellin6076|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Solibacter usitatus (strain Ellin6076) Length = 269 Score = 195 bits (475), Expect = 1e-48 Identities = 98/216 (45%), Positives = 136/216 (62%), Gaps = 3/216 (1%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 ++G+ L++P+ K++C+GLNY+DH EE K+ PE P +F K+ +TV G I L + Sbjct: 47 VAGMKLRSPLQRPGKIICIGLNYRDHAEEAKMPIPETPTVFAKWGNTVTGHQHPIVLPKN 106 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 S+ E EL VVIGK + ++ ++V GYTI D+ A D++ SQ +GK Sbjct: 107 -SRKPDYEAELAVVIGKGGRHIAEANWREHVFGYTILNDVSARDFQM--ATSQWTIGKTF 163 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 DTF PIGPWIVT+DEI +P L + ++N V Q SNT+ I IP +IA LS+VM+L P Sbjct: 164 DTFAPIGPWIVTTDEIEDPGALRISLTLNSVTMQDSNTSNLIFGIPKLIAYLSSVMSLEP 223 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 GDII TGTP GVG + PP +L PGDV ++ IG Sbjct: 224 GDIISTGTPAGVGFAQKPPRWLVPGDVCAIQVGGIG 259 >UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Roseiflexus|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Roseiflexus sp. RS-1 Length = 288 Score = 194 bits (473), Expect = 2e-48 Identities = 109/283 (38%), Positives = 151/283 (53%), Gaps = 10/283 (3%) Query: 7 SYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXXLSGITL 66 +Y++S+ + G L GD VV + P + S LI+ LS +TL Sbjct: 5 TYRDSESVHLGALRGDEVVSLADVAPDMLS-LIDAGPAGLEAARAAVERGAGVPLSAVTL 63 Query: 67 KAPV-HGNDKVLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKM 119 AP+ V+C+G+NY H E ++ PE P F K TV GP+D I L Sbjct: 64 LAPIPRPRQNVICLGMNYVAHTIESYRARGREPKMPEYPVFFTKAAHTVCGPDDDIPLDP 123 Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179 V+ + E+EL +IGK V A +YV GYTI DI A D + + Q GK+ Sbjct: 124 KVTNELDYEVELAFIIGKAGMNVPRDEAMEYVFGYTIVNDISARDLQSRHQ--QFFKGKS 181 Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 + CP+GP IVT+DEI NP L ++ +NG +Q S+T I IP II LS M L Sbjct: 182 LYRACPMGPCIVTTDEIPNPAGLGIRLRLNGETRQDSHTGDLIFDIPAIIEHLSLGMPLE 241 Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 PG I+ TGTP GVG+ R PPE+++PGDV+ +EI++IG R+ Sbjct: 242 PGMIVATGTPAGVGLGRTPPEYMRPGDVMEAEIDSIGILRNRI 284 >UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Oceanobacillus iheyensis|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Oceanobacillus iheyensis Length = 301 Score = 194 bits (472), Expect = 3e-48 Identities = 96/224 (42%), Positives = 138/224 (61%), Gaps = 3/224 (1%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L+ I L P+ KV+CVG NY +H E K PE P +F KF + ++GP + I Sbjct: 80 LNEIQLGMPLGTARKVICVGKNYAEHVAEMKSEIPEFPVLFAKFDNAIIGPEEEIHYS-S 138 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 +++ + E+ELT+VIG++AS V A DYV GYTI D A D +K + Q L GK++ Sbjct: 139 LTEKLDYEVELTIVIGREASHVFEEEALDYVAGYTIGNDTSARDLQK--RTPQWLQGKSL 196 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 D PIGPW+VT DEI +P NL + +N ++Q SNT I +P +++ +SN++TL P Sbjct: 197 DHTTPIGPWVVTKDEIVDPGNLTIASYVNNEKRQYSNTKHLIFSVPYLVSFISNLITLKP 256 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 GDII+TGTP GVG +PP +++ D + EIE IG E V++ Sbjct: 257 GDIIMTGTPDGVGFAMDPPGYVKDKDKVKLEIEGIGIMENMVKK 300 >UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=6; Burkholderiales|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Burkholderia cenocepacia (strain HI2424) Length = 293 Score = 188 bits (458), Expect = 1e-46 Identities = 102/236 (43%), Positives = 141/236 (59%), Gaps = 15/236 (6%) Query: 61 LSGITLKAPV-HGNDKVLCVGLNYKDHCEEQKLT-----------PPELPFIFNKFPSTV 108 L+ T+ AP+ + CVG NY +H E + + PE P IF K STV Sbjct: 61 LAEATILAPIDQPRRNIFCVGKNYHEHAAEFQNSGFDSSAKNGEHAPEAPVIFTKPASTV 120 Query: 109 VGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN 168 +GP+ I + V+ + E EL VVIGK + + A +YV GYT+ D A D +K Sbjct: 121 IGPSAKIPRHVGVTAQLDYEAELGVVIGKGGRGIKKADAMNYVFGYTVINDFTARDLQKL 180 Query: 169 KKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDI 228 + Q LGK++D FCP+GP+++TSDE+ N QN+++KC +NG +Q SNT++ I IP + Sbjct: 181 HR--QWFLGKSLDGFCPMGPFVITSDEV-NGQNIDIKCWVNGELRQNSNTSKLIFDIPTL 237 Query: 229 IARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 I LS + L PGD+I TGTP GVG+ NPP+FLQ GDVI EI+N+G E V E Sbjct: 238 IETLSAGIELQPGDVIATGTPAGVGIGFNPPKFLQKGDVIRIEIQNVGVLENEVGE 293 >UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Opitutaceae bacterium TAV2|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Opitutaceae bacterium TAV2 Length = 279 Score = 188 bits (457), Expect = 2e-46 Identities = 96/208 (46%), Positives = 120/208 (57%), Gaps = 1/208 (0%) Query: 76 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV-SKAVVCEIELTVV 134 +LC+GLNY+ H EE PE P +F K + + P D I L + S V E EL VV Sbjct: 69 ILCIGLNYRRHAEETHARIPEFPVLFMKGVNALQNPGDPIMLPTHLRSDEVDYECELAVV 128 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IG+ V HA DYVLGYT A D+ A DW+ + SQ GK DTF P+GP IVT D Sbjct: 129 IGRTCKNVTRDHALDYVLGYTCANDVSARDWQVKRGGSQWCRGKTFDTFAPLGPAIVTKD 188 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 EI NP L + +++G Q T+ I +P +I LS TLLPG +ILTGTP GVG+ Sbjct: 189 EIPNPNALKISTTVSGEVLQDWTTSDMIFDVPALIEFLSGSTTLLPGTVILTGTPHGVGM 248 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282 R PP +L+ GD + EIE IG E V Sbjct: 249 ARKPPRWLRAGDKVVVEIEKIGRLENPV 276 >UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 295 Score = 187 bits (455), Expect = 3e-46 Identities = 93/219 (42%), Positives = 134/219 (61%), Gaps = 2/219 (0%) Query: 66 LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125 L APV K++ +GLNY+DH E PE P +F K+ +T+VG + +++ S+A Sbjct: 78 LHAPVLNPQKIIAIGLNYEDHANETGAPIPEKPIVFAKYANTLVGAGEEVRIPPITSQAD 137 Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185 E EL VVIG++A V A +YV GYT D+ + D + ++ Q K++DTFCP Sbjct: 138 Y-EAELAVVIGREAKNVSEEEALEYVFGYTNCNDVSSRDLQFSEG-GQWTRSKSLDTFCP 195 Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 +GP++ T DEI +PQ+L ++ +NG Q SNT++ I + +I+ LS MTL+PGDII Sbjct: 196 LGPYVATRDEIPDPQSLRIRSVLNGEVMQDSNTSKMIFPVARLISFLSTGMTLVPGDIIA 255 Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 TGTP GVG R+P FL+ GD I+ EIE +G V E Sbjct: 256 TGTPAGVGFARDPKVFLKDGDEISIEIEGLGRLTNPVRE 294 >UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Acidobacteria bacterium Ellin345|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Acidobacteria bacterium (strain Ellin345) Length = 290 Score = 186 bits (454), Expect = 4e-46 Identities = 99/223 (44%), Positives = 133/223 (59%), Gaps = 4/223 (1%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 + G L PV K++ +GLNY DH +E + P+ P F KF S++ GP D I+L D Sbjct: 69 VDGRDLDFPVAAK-KIVAIGLNYLDHAKEAGQSIPKTPLCFAKFTSSLSGPYDPIRLP-D 126 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 V E EL VVIGK+A +V S A +YV GY + D+ ++ Q GK+ Sbjct: 127 AEAQVDFEGELGVVIGKRAHRVAESEAMEYVAGYVVFNDV--SERRSQFADGQWTRGKSC 184 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 DTF P GP++VT DE+ +P NL + +NG Q SNTNQ I KIP++I+ LS+ T P Sbjct: 185 DTFSPNGPYLVTRDEVADPGNLRITTRVNGAVMQDSNTNQLIFKIPELISYLSHSFTFHP 244 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 GDII TGTP GVG R PP +L+ GD++ EIE++G RVE Sbjct: 245 GDIIATGTPPGVGFSRKPPLYLREGDLVEVEIESVGRIANRVE 287 >UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Bacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 302 Score = 185 bits (450), Expect = 1e-45 Identities = 97/226 (42%), Positives = 134/226 (59%), Gaps = 10/226 (4%) Query: 64 ITLKAPVHGNDK-VLCVGLNYKDHCEEQKLTP------PELPFIFNKFPSTVVGPNDTIK 116 +TL AP+ K + +GLNY +H E P+ P IF+K P+ V ND I+ Sbjct: 77 VTLLAPIPRPRKNIFGIGLNYTEHVAESARALDTAHELPQQPVIFSKPPTAVAAWNDPIR 136 Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176 V++ + E EL V+IG A V + A ++V GYT+ D+ A D ++ Q ++ Sbjct: 137 HNAKVTQQLDWETELAVIIGSTARGVAEADALNHVFGYTVINDVSARDC---RRAGQWIV 193 Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236 K D+F P+GP IVT+DEIG+P NLN+ +NGV+KQ SNT + +P +IA ++ VM Sbjct: 194 SKGQDSFAPMGPCIVTADEIGDPHNLNILTHVNGVEKQNSNTRFMLFNVPQLIADIARVM 253 Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TL PGDII TGTP GVG R+P EFL PGDV+ +E IGT V Sbjct: 254 TLEPGDIIATGTPAGVGAGRDPQEFLWPGDVVECTVEGIGTLRNPV 299 >UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Bacillus clausii KSM-K16|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Bacillus clausii (strain KSM-K16) Length = 292 Score = 183 bits (446), Expect = 4e-45 Identities = 93/224 (41%), Positives = 136/224 (60%), Gaps = 5/224 (2%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 + T + +K++C+GLNY+ H +E PE P +F+KF +T+ G I + Sbjct: 68 IESCTFGPAIPNPEKIICIGLNYRRHADETGSPYPETPILFSKFNNTLTGHGSNIVVP-P 126 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 V++A+ E+EL +VIGK A +V A +YVLGY A D+ A D + K +Q LLGK Sbjct: 127 VTQALDYEVELAIVIGKTAKQVTEDEALNYVLGYCTANDLSARDLQM--KTAQWLLGKTC 184 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 D FCPIGP++VT ++I +PQNL ++ +NG KQ+SNT I +II+ +S TL P Sbjct: 185 DGFCPIGPFLVTKEDIADPQNLALETRVNGEIKQQSNTADMIFTCAEIISYVSRHFTLKP 244 Query: 241 GDIILTGTPGGV--GVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GDI+LTGTP GV G+ +LQPGD ++ IE +GT ++ Sbjct: 245 GDILLTGTPEGVILGLPEAERRYLQPGDTVSVHIEQLGTLTNKL 288 >UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=3; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Neptuniibacter caesariensis Length = 286 Score = 183 bits (445), Expect = 5e-45 Identities = 100/222 (45%), Positives = 127/222 (57%), Gaps = 4/222 (1%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L+ ++L APV K L VGLNY DH EE L PE P FNK S V+GPN+ I + Sbjct: 60 LNEVSLLAPVASPQKFLGVGLNYADHIEETGLDTPEFPTFFNKQSSCVIGPNEAIH-RPT 118 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 VS+ + E EL +VIGK V A + + G+TI D+ DW+ K LGK+ Sbjct: 119 VSEKLDYEGELAIVIGKACRHVPYEKASEVIAGFTIVNDVSVRDWQI--KSPTWTLGKSF 176 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 DT P+GPWIVT+DE+ NP NL +K +N +Q SNT I +I LS V TL P Sbjct: 177 DTHGPMGPWIVTADEV-NPHNLELKTWVNDELRQHSNTKHLIFDCYQLIETLSTVCTLQP 235 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GD+I TGT GVGV P +++PGD +T EIE IG V Sbjct: 236 GDVIATGTSSGVGVKMKPRGYMKPGDRVTIEIEGIGKLSNPV 277 >UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Symbiobacterium thermophilum|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Symbiobacterium thermophilum Length = 294 Score = 182 bits (443), Expect = 9e-45 Identities = 93/220 (42%), Positives = 133/220 (60%), Gaps = 3/220 (1%) Query: 63 GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122 G+ L PV K+LCVGLNY+ H E + P P +F KF + V GP D + L ++ Sbjct: 74 GLRLGPPVPRPGKILCVGLNYRAHAAEAHMAVPAYPVLFAKFQNAVAGPGDPVVLP-SIA 132 Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDT 182 + E EL VVIG++A +V + A DYVLGY D+ A E + SQ LLGK++D Sbjct: 133 EQYDYEAELVVVIGRRARRVPAEAALDYVLGYCNGNDLSAR--ELQMRTSQWLLGKSLDG 190 Query: 183 FCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGD 242 F PIGP++VT DE+ +PQ+L ++ NG +Q +T + + ++IA +S MTL PGD Sbjct: 191 FLPIGPYLVTRDEVPDPQDLRIRLWRNGEIRQDGHTRNMLFPVAELIAYISRYMTLEPGD 250 Query: 243 IILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 II TGTP GV + ++L+PGDV+ EI+ +G E R+ Sbjct: 251 IIATGTPEGVIMGLAEKDWLKPGDVVAVEIDGLGRLENRL 290 >UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family protein; n=2; Candidatus Pelagibacter ubique|Rep: Fumarylacetoacetate hydrolase family protein - Pelagibacter ubique Length = 281 Score = 180 bits (438), Expect = 4e-44 Identities = 86/204 (42%), Positives = 129/204 (63%), Gaps = 2/204 (0%) Query: 79 VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 138 +GLNY +H +E P+ P +FNK ++VGPND + + SK + E+E+ VIGKK Sbjct: 76 IGLNYVEHAKETGAKTPDNPVLFNKSVHSIVGPNDNVIIPK-TSKKLDHEVEIAFVIGKK 134 Query: 139 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 198 A +V A DY+ GY I DI +W+K K Q + GK+ DTF P+GP++VT DEI + Sbjct: 135 AKRVLEKDAQDYIFGYCICNDISEREWQKEKG-GQWVKGKSGDTFGPLGPYLVTKDEIQD 193 Query: 199 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 258 NLN+ +NG + Q NTNQ I ++A +++ +TL+PGDI+ TGTP GVG+ +P Sbjct: 194 VNNLNLTLDVNGHRHQTGNTNQMIFNFNFLVAHITSFITLMPGDIVTTGTPPGVGLGMDP 253 Query: 259 PEFLQPGDVITSEIENIGTFETRV 282 P FL+ GD + I+++G+ ++V Sbjct: 254 PVFLKEGDEMKLNIDSLGSQNSKV 277 >UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase; n=1; Pedobacter sp. BAL39|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase - Pedobacter sp. BAL39 Length = 285 Score = 177 bits (432), Expect = 2e-43 Identities = 88/220 (40%), Positives = 127/220 (57%), Gaps = 2/220 (0%) Query: 66 LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125 L +P+ K++C+GLNY DH E P P +F K + +VGP D I + K Sbjct: 65 LGSPIGRPSKLVCIGLNYADHARETNAPLPPEPVVFMKSTTAIVGPFDQIMIPKGSVKTD 124 Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185 E+EL +VIGKKAS V+ + A DYV GY + D+ +++ + GK DTF P Sbjct: 125 -WEVELAIVIGKKASYVEEAEALDYVAGYVLHNDVSEREFQIERN-GTWDKGKGCDTFAP 182 Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 +GP++ T +EI + NL + S+NG Q NT+ FI +P +++ +S MTLLPGD+I Sbjct: 183 LGPFLATKEEIADVNNLRLWLSVNGKMMQDGNTSNFIFNVPFVVSYVSQFMTLLPGDVIS 242 Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285 TGTP GVG+ PP +L+ GDV+ I+ +GT V F Sbjct: 243 TGTPAGVGLGFKPPVYLKAGDVVELGIDGLGTSRQEVIAF 282 >UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Bacillus sp. B14905|Rep: Fumarylacetoacetate hydrolase family protein - Bacillus sp. B14905 Length = 314 Score = 177 bits (432), Expect = 2e-43 Identities = 84/204 (41%), Positives = 125/204 (61%), Gaps = 5/204 (2%) Query: 76 VLCVGLNYKDHCEEQ--KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133 ++C+G NY +H +E + P EL +F K P+ + T+ + D+S + E EL + Sbjct: 94 IMCIGKNYNEHAKEMGAEAAPKEL-MVFTKSPTAIAADGQTLSIHADLSSKMDYEGELAI 152 Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193 VIGK+ + + A+DYV GYTIA DI A D ++ K Q LGK+++ CP+GP++VT Sbjct: 153 VIGKRGKNIPKNLAYDYVFGYTIANDITARDLQEKHK--QFFLGKSLEGTCPLGPYLVTK 210 Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 DEI NPQ+L V +N +Q +T + + +++ LS +TL PGD+ILTGTP GVG Sbjct: 211 DEIPNPQDLTVVTKVNDEVRQNGSTKDMMFSVETLVSILSQHVTLEPGDVILTGTPAGVG 270 Query: 254 VYRNPPEFLQPGDVITSEIENIGT 277 NPP+FL+ GD + I+ IGT Sbjct: 271 KGMNPPQFLKAGDTVKVSIQGIGT 294 >UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=5; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Dinoroseobacter shibae DFL 12 Length = 308 Score = 177 bits (430), Expect = 3e-43 Identities = 95/222 (42%), Positives = 128/222 (57%), Gaps = 8/222 (3%) Query: 68 APVHGNDK-VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 AP+H K + CVG NY +H E K+ E P F K + VVG + + Sbjct: 85 APLHTPRKNIFCVGRNYAEHIAEGERAQNAKIGITEHPVYFTKPATAVVGHGGDVLIFPS 144 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 VS+ + E+EL VVIG + AF +V GYTI DI A D ++ Q GK++ Sbjct: 145 VSEKIDYEVELAVVIGTTGRDIPKDRAFAHVFGYTILNDITARDVQRRHG-GQYFKGKSL 203 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 D CPIGPWIVT+DEI +PQ+L++ S+NG +Q T+ I IP +IA LS +TL P Sbjct: 204 DGSCPIGPWIVTADEITDPQDLSISLSVNGELRQNGWTHDMIFDIPTLIASLSEGLTLEP 263 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GDII TGTP GVG +PP++L+PGD + +I NIG + V Sbjct: 264 GDIIATGTPSGVGYAMDPPQYLKPGDTVICDIANIGQLKNTV 305 >UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=8; cellular organisms|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Thermoanaerobacter tengcongensis Length = 242 Score = 176 bits (429), Expect = 5e-43 Identities = 100/209 (47%), Positives = 129/209 (61%), Gaps = 13/209 (6%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K +CVGLNYKDH EE PE P +F K + V+GP+D I L ++S+ V E EL VV Sbjct: 47 KAICVGLNYKDHIEEMGDKIPEEPTLFIKPSTAVIGPDDYIILP-EMSRRVDYEGELAVV 105 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IG+KA V A +Y+LGYTIA D+ A D + K Q K+ DTF PIGPWIVT Sbjct: 106 IGRKAKNVSIEEAKNYILGYTIANDVTARDLQA--KDGQWTRAKSFDTFLPIGPWIVTDL 163 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 + P +LN+ +NG KQKSNT I + +++ +S++MTL PGD+ILTGTP GVG Sbjct: 164 D---PTSLNITTYVNGEVKQKSNTKYLIFNVFKLVSFISHIMTLNPGDVILTGTPSGVGP 220 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRVE 283 L+ GDV+T EIE IG RV+ Sbjct: 221 -------LKSGDVVTIEIEGIGKLTNRVK 242 >UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17; Staphylococcus|Rep: Uncharacterized protein SH1982 - Staphylococcus haemolyticus (strain JCSC1435) Length = 301 Score = 176 bits (429), Expect = 5e-43 Identities = 107/301 (35%), Positives = 150/301 (49%), Gaps = 22/301 (7%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDNVVDINK------EDPKLPSTLIELLKTNXX------- 47 MK L F+YK+++ D V D+ K E P TL+E L+ N Sbjct: 1 MKFLSFNYKDAESYGVKVKRKDAVWDLKKVFAEFGEGDFHPQTLLEGLQQNQTLDFQEQV 60 Query: 48 ------XXXXXXXXXXXXXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIF 101 + I PV + V+ G NY+DH E L ++F Sbjct: 61 RKAVVAAEDSGKADEFKIAFNDIEFLPPVTPPNNVIAFGRNYQDHASELNHEVQRL-YVF 119 Query: 102 NKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIG 161 K S++ G TI D++ + E EL +VIGK K+ + A DY+ GYTI DI Sbjct: 120 TKAASSLTGDESTIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYIYGYTIINDI- 178 Query: 162 ATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQF 221 TD + + Q L K++ CP+GP+IVT DE+ P+N+N+ +N +Q NT+Q Sbjct: 179 -TDRKAQNEQDQAFLSKSLTGGCPMGPYIVTKDELPTPENVNIVTKVNNDIRQDGNTSQM 237 Query: 222 IHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETR 281 I+KI D+I +S + L PGDII TGTP GVG PP+FLQPGD + I+NIGT T Sbjct: 238 INKIDDLIEEISKYVALHPGDIIATGTPAGVGAGLQPPQFLQPGDEVKVTIDNIGTLTTY 297 Query: 282 V 282 + Sbjct: 298 I 298 >UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=13; Proteobacteria|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Rhodopseudomonas palustris Length = 280 Score = 175 bits (427), Expect = 8e-43 Identities = 85/211 (40%), Positives = 126/211 (59%), Gaps = 2/211 (0%) Query: 66 LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125 L +PV G K + +GLNY DH E + P P +F K +++ GPND ++ K S + Sbjct: 63 LGSPVGGAPKFIAIGLNYADHAAEANMPIPAEPIVFMKAINSLCGPNDDVE-KPRGSTKL 121 Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185 E+EL V+IG +A V + A +YV GY + D+ +++ ++ Q GK+ DTF P Sbjct: 122 DWEVELAVIIGTRAKYVTEADALNYVAGYAVCNDVSERNFQL-ERAGQWTKGKSHDTFGP 180 Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 +GPW+ T DEI + L + +NG ++Q +T I +P I++ LS +MTL+PGDII Sbjct: 181 LGPWVATKDEIADVHKLGMWLDVNGQRRQTGSTATMIFNVPKIVSYLSELMTLMPGDIIT 240 Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 TGTP GVG PP++L GDV+T IE +G Sbjct: 241 TGTPPGVGTGMKPPQYLNVGDVVTLGIEGLG 271 >UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1; Clostridium kluyveri DSM 555|Rep: Putative uncharacterized protein - Clostridium kluyveri DSM 555 Length = 301 Score = 175 bits (427), Expect = 8e-43 Identities = 110/300 (36%), Positives = 157/300 (52%), Gaps = 22/300 (7%) Query: 1 MKLLQFSYKNSDGIRA----GFLDGDNVV-DINKEDPKLPSTLIELLK------TNXXXX 49 MK + + YK + I L+ +++ +I +E+P P ++EL+K N Sbjct: 1 MKFVTYDYKGKENIGILKDKSILNFESIFYEIGEENP--PKDMVELIKYLDEDKLNEVEE 58 Query: 50 XXXXXXXXXXXLSGITLKAPV-HGNDKVLCVGLNYKDHCEEQKLTP------PELPFIFN 102 L + LKAP+ + V C+G NY++H E KLT P++P F Sbjct: 59 FLKSKSLQGVFLDTVKLKAPIPYPKRNVFCLGKNYEEHAREIKLTRITGNEIPKVPIYFT 118 Query: 103 KFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGA 162 K S +G D+I+ +V+ V E+EL VVIGK + A Y+ GYTI DI A Sbjct: 119 KVASPAIGNGDSIEFSSEVTNQVDYEVELGVVIGKNGKNIKKEEAEKYIFGYTIINDISA 178 Query: 163 TDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFI 222 D + + Q GK++DTFCP+GP IV +EI P NL++KC +N +Q SNT I Sbjct: 179 RDLQGSH--IQWFKGKSLDTFCPMGPCIVHKNEIPFPINLDIKCWVNEELRQDSNTKNLI 236 Query: 223 HKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 IP II+ LS ++L GDII TGTP GVG+ +P + L+ GD I IE IG+ V Sbjct: 237 FDIPYIISDLSKGVSLKAGDIIATGTPSGVGMGFSPIKVLKQGDSIECYIEKIGSLVNNV 296 >UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=2; Proteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Acidovorax sp. (strain JS42) Length = 281 Score = 175 bits (425), Expect = 1e-42 Identities = 97/278 (34%), Positives = 146/278 (52%), Gaps = 8/278 (2%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDNVV-DINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXX 59 MKL++ ++ RAG +D V+ D++ P + T +L Sbjct: 1 MKLVRHGQPGAE--RAGLIDAQGVLRDLSMLLPDIGPT--QLAPRTLAALAAIDAARLPA 56 Query: 60 XLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM 119 + G L PV G K++CVGLNY DH E L P P +F K S + GP D +++ Sbjct: 57 VVPGTRLGCPVGGVGKIVCVGLNYADHAAEAGLPAPAEPVLFMKATSALSGPTDAVRIPP 116 Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179 K E+EL +VIG + +V + A +V GY +A D+ ++ + Q GK Sbjct: 117 GALKTD-WEVELGIVIGTRMQQVAEADALAHVAGYVLANDVSERSYQMERG-GQWDKGKG 174 Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 DTF P+GPW+VT+DEI +P + + +NG + Q +T FI +P ++A +S MTL Sbjct: 175 CDTFAPVGPWLVTTDEIPDPHAIGLWLEVNGQRMQDGHTRNFIFGVPRVLAYISQFMTLE 234 Query: 240 PGDIILTGTPGGVGVYRNP-PEFLQPGDVITSEIENIG 276 PGD++LTGTP GVG+ + P P FL+ GDV+ +G Sbjct: 235 PGDLVLTGTPAGVGLGQKPTPRFLRAGDVMRLGATGLG 272 >UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family protein; n=21; Firmicutes|Rep: Fumarylacetoacetate hydrolase family protein - Bacillus anthracis Length = 302 Score = 174 bits (424), Expect = 2e-42 Identities = 92/226 (40%), Positives = 131/226 (57%), Gaps = 5/226 (2%) Query: 61 LSGITLKAPVHGNDK-VLCVGLNYKDHCEEQKLTP--PELPFIFNKFPSTVVGPNDTIKL 117 L+ + + AP+ K +LCVG NY++H E PE IF K P+TV+G ++ I Sbjct: 79 LTEVKILAPIPRPRKNILCVGKNYREHAIEMGGVESIPENIMIFTKAPTTVIGMDEKINS 138 Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177 + + E EL +VIGK+ ++ A ++V GYTI DI A D ++ K Q LG Sbjct: 139 HPHATNELDYEGELAIVIGKRGKQIKKEKALEHVFGYTIINDITARDIQRKHK--QFFLG 196 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 K+ DTFCP+GP+++ I P L+++ +NG +Q SNTN+ I I +II+ +S MT Sbjct: 197 KSFDTFCPMGPYLIHKSMISTPNALHIETIVNGEVRQTSNTNKMIFSIEEIISTISKGMT 256 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 L PGDII TGTP GVG PP+FL GD + +E IGT V+ Sbjct: 257 LEPGDIIATGTPAGVGKGFTPPKFLHAGDEVVITVEGIGTLRNVVK 302 >UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase precursor; n=3; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase precursor - Polynucleobacter sp. QLW-P1DMWA-1 Length = 349 Score = 174 bits (423), Expect = 2e-42 Identities = 89/215 (41%), Positives = 123/215 (57%), Gaps = 9/215 (4%) Query: 76 VLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 127 + CVG NY DH EE P++P +F K T+ GP D I +S + Sbjct: 135 IYCVGWNYLDHFEEGLKHRADTAVKEYPKVPVLFTKGTQTMNGPFDNIPYDAGISTMIDW 194 Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187 E EL VVIGKK + +A DYV GY+ D A D ++ ++ Q GK++D P+G Sbjct: 195 EAELAVVIGKKGKNISEENAMDYVFGYSAYNDTTARDIQQKRQSGQWFKGKSLDGHGPMG 254 Query: 188 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247 PW+VT+ + N + + CS+NGV+KQ ++ Q KIP IIA LS +TLLPGDII TG Sbjct: 255 PWVVTAGGV-NLDDTRIICSVNGVEKQNASYKQMYFKIPAIIAELSRGLTLLPGDIIATG 313 Query: 248 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TP GVG R P EF++PGD++ + I IG ++ Sbjct: 314 TPSGVGAGRTPQEFMKPGDMMETNITGIGILRNKI 348 >UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family protein; n=8; Proteobacteria|Rep: Fumarylacetoacetate hydrolase family protein - Silicibacter pomeroyi Length = 305 Score = 173 bits (420), Expect = 6e-42 Identities = 86/226 (38%), Positives = 138/226 (61%), Gaps = 10/226 (4%) Query: 64 ITLKAPVHGNDK-VLCVGLNYKDHCEEQKLTP------PELPFIFNKFPSTVVGPNDTIK 116 + L AP+ K + +GLNY +H E + P+ P +F+K P++V+ + I+ Sbjct: 78 VRLLAPIPRPRKNIFGIGLNYVEHVAESAKSLDTSKELPKEPVVFSKPPTSVIASGEGIQ 137 Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176 +++ + E+EL V+IGK+A+++ +A +V GY++ D+ A D N++ Q + Sbjct: 138 HNAAMTQQLDWEVELAVIIGKRATRIAKDNAMSHVFGYSVINDVSARD---NRRAGQWIF 194 Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236 K DTFCP GP I+T+D++ +P NL++ + NGV+KQ+SNT + IP +IA +S+ + Sbjct: 195 SKGQDTFCPFGPAIITADDVPDPHNLDLWLTKNGVEKQRSNTRHLLFDIPTLIADISSGI 254 Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TL PGDII TGTP GVG R+P E++ PGDVI ++ IG V Sbjct: 255 TLEPGDIIATGTPAGVGAGRDPQEWMWPGDVIECGVDGIGVLRNPV 300 >UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=4; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Silicibacter sp. (strain TM1040) Length = 281 Score = 172 bits (419), Expect = 7e-42 Identities = 84/202 (41%), Positives = 121/202 (59%), Gaps = 2/202 (0%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K +C+GLNY DH E ++ PE P IF K S + GPND +++ S E+EL VV Sbjct: 72 KFICIGLNYADHAAESGMSLPEEPVIFFKATSAICGPNDAVEIPR-TSVKTDWEVELGVV 130 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IGK A + A D+V GY + D+ D++ ++ Q + GK+ DTF PIGPW+VT D Sbjct: 131 IGKTAKYIGRDEALDHVAGYCVVNDLSERDFQLHRS-GQWVKGKSADTFGPIGPWLVTRD 189 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 E+ +PQNL + +NG + Q +T + +I+ LS M+L PGD+I TGTP GVG+ Sbjct: 190 EVPDPQNLAMWLEVNGHRYQDGSTRTMHFDVATVISHLSQFMSLQPGDVISTGTPPGVGM 249 Query: 255 YRNPPEFLQPGDVITSEIENIG 276 + P +L+PGDV+ I +G Sbjct: 250 GQTPETYLKPGDVMELGIAGLG 271 >UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4; Thermoprotei|Rep: Fumarylacetoacetate (FAA) hydrolase - Sulfolobus acidocaldarius Length = 307 Score = 172 bits (419), Expect = 7e-42 Identities = 93/219 (42%), Positives = 129/219 (58%), Gaps = 6/219 (2%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128 PV +K+ + +NY+ H +E PP+ P+IF KF +T++G N + L S V E Sbjct: 90 PVTDPEKIFLLAVNYRAHGQETNNNPPKEPYIFTKFNNTLIGHNQPV-LFPRASNKVDYE 148 Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS---QLLLGKAMDTFCP 185 IEL V++GK+A V+SS A DYV GYTI DI D + +I + + GK +DT P Sbjct: 149 IELAVIMGKRAKYVNSSKALDYVFGYTIFNDISFRDKQFPPEIPYGMRWVHGKGLDTAAP 208 Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 +GPWIVT DEI N NL +K +NG +Q + I K+ II LSN +TL PGD+I Sbjct: 209 MGPWIVTKDEIDNINNLRLKLRVNGEIRQDAYAEDMIFKVEQIIEYLSNGITLKPGDVIS 268 Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 TGTP GV + ++L+PGDV+ +EI IG + E Sbjct: 269 TGTPSGVALATG--KYLKPGDVMEAEISKIGVLRNNLIE 305 >UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4; Euryarchaeota|Rep: Uncharacterized protein MJ1656 - Methanococcus jannaschii Length = 237 Score = 171 bits (417), Expect = 1e-41 Identities = 92/210 (43%), Positives = 126/210 (60%), Gaps = 13/210 (6%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++CVGLNY DH +E + PE P IF K S ++ D I ++ +SK V E+EL +V Sbjct: 39 KIICVGLNYIDHAKELNMEIPEYPIIFLKPTSAIIYNEDYI-IRPRISKRVDYEVELAIV 97 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IGKK + A DY++GYTI D+ A D ++ K Q K+ DTFCPIGP IV Sbjct: 98 IGKKCKNIKKDEANDYIMGYTILNDVTARDLQQ--KDGQWTRAKSFDTFCPIGPRIVKDI 155 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 + P NLN++C +NG KQKSNT I + +++ ++++MTL PGDII TGTP GVG Sbjct: 156 D---PMNLNIECRVNGEIKQKSNTKNMIFDVYELVEFVASIMTLYPGDIISTGTPPGVGE 212 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRVEE 284 L+ GDV+ EIE IG V++ Sbjct: 213 -------LKAGDVVECEIEGIGILRNYVKD 235 >UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative fumarylacetoacetate hydrolase - Aurantimonas sp. SI85-9A1 Length = 293 Score = 171 bits (416), Expect = 2e-41 Identities = 93/233 (39%), Positives = 134/233 (57%), Gaps = 12/233 (5%) Query: 62 SGITLKAPVHGNDK-VLCVGLNYKDHCEE---------QKLTPPELPFIFNKFPSTVVGP 111 S +T+ AP+ + + CVG NY++H E K P P IF K S ++GP Sbjct: 63 SEVTILAPLPETRRDIFCVGKNYREHASEFHNSGFDSGGKQAIPVAPVIFTKSLSAIIGP 122 Query: 112 NDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKI 171 TI+ +D ++ V E EL VVIGK+A V + A DYV GY + D+ T E + Sbjct: 123 GATIEAGLDRTRTVDYEGELGVVIGKRAFGVTKADAMDYVFGYVVINDV--TSRELQRHH 180 Query: 172 SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIAR 231 SQ ++GK +DTF P+GP +VT+DE+ + L V ++NG +QK++ I IP +I Sbjct: 181 SQWVIGKGIDTFAPMGPVLVTADEVPDVTKLTVTTTVNGETRQKASVAGLIFDIPTLIET 240 Query: 232 LSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 ++ MTLLPGDII TGTP GVG+ +PP +L GD + I+ +GT E V + Sbjct: 241 MTATMTLLPGDIIATGTPAGVGIGFDPPRYLADGDRVAVTIDGLGTLENPVRQ 293 >UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Picrophilus torridus|Rep: Fumarylacetoacetate hydrolase family protein - Picrophilus torridus Length = 281 Score = 170 bits (414), Expect = 3e-41 Identities = 95/222 (42%), Positives = 132/222 (59%), Gaps = 7/222 (3%) Query: 62 SGITLKAPVHGN-DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKLKM 119 +GI P N +K++CVG NYK+H E PE P +F+KF +T+ G ND I + Sbjct: 59 TGIDKYGPAISNPEKIICVGKNYKEHALETGSGIPESPVLFSKFNNTLTGHLNDII---I 115 Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179 D S ++ E EL +VIGKKA VD + A DYV GY IA D+ A D + + SQ LLGK Sbjct: 116 DFSDSIDYEGELGIVIGKKARNVDENDAMDYVFGYYIANDVSARDLQY--RTSQWLLGKT 173 Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 D F P GP+IVT DE+ +P NL+++ NG Q SNT I I +I +S +TL+ Sbjct: 174 PDGFYPNGPFIVTKDEVNDPMNLDIRTLRNGDTVQHSNTRNMIFDIKYLIGYISKYLTLM 233 Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETR 281 PGD+I TGTP GV + N +++ + I +IE +G+ + R Sbjct: 234 PGDVISTGTPEGVILGTNEKNWIKNNETIEVKIEKLGSLKNR 275 >UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctional decarboxylase/isomerase; n=4; Pezizomycotina|Rep: Function: E. coli hpaG is a bifunctional decarboxylase/isomerase - Aspergillus niger Length = 358 Score = 169 bits (412), Expect = 5e-41 Identities = 93/221 (42%), Positives = 128/221 (57%), Gaps = 6/221 (2%) Query: 66 LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125 L PV V+C+GLNYK H +E L P P +F K + GP +TI + D + Sbjct: 54 LLPPVPNTPLVICIGLNYKQHAKEASLDVPTYPPVFTKPADVLAGPFETIPIHRDAQSHL 113 Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKI-SQLLLGKAMDTFC 184 E ELTVVIGK A V + A DYVLGYT D+ A +++ + Q K+ D F Sbjct: 114 DYEGELTVVIGKDAKNVSAEDALDYVLGYTAGNDLSARNFQMPEASGGQFCYAKSFDKFA 173 Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244 PIG +V++ E+ +PQ L++ +NGV KQ +NT+ I + DI++ LS MTL G +I Sbjct: 174 PIGHVLVSAQEVQDPQQLSLVTKVNGVVKQTTNTSDMIWGVRDIVSHLSRGMTLRKGTLI 233 Query: 245 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285 +TGTP GVG +R EFLQ GDV+ E+E +G E V +F Sbjct: 234 MTGTPSGVGFFRK--EFLQDGDVV--EVE-LGVREPGVIDF 269 >UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Candidatus Nitrosopumilus maritimus SCM1 Length = 289 Score = 169 bits (412), Expect = 5e-41 Identities = 90/223 (40%), Positives = 126/223 (56%), Gaps = 3/223 (1%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 LS L AP+ +K++C+ NY DH +EQ LT PE P I K + + G N I+ D Sbjct: 65 LSKFKLLAPIPNPNKIICLAFNYVDHAKEQGLTAPEDPAIVIKPRTALNGNNANIECP-D 123 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 + E+EL ++IGK + A + V GY + D+ A D + K Q GK+ Sbjct: 124 FVTQLDYEVELALIIGKNCKNISVEEAQNVVFGYMVFNDVSARDIQFKDK--QFTRGKSF 181 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 D+F P GPWI T+DEI PQNL + ING +Q S+T+ KIP+II+++S VMTL Sbjct: 182 DSFAPCGPWITTADEIQEPQNLKLTTKINGELRQNSSTSNMFIKIPEIISKISKVMTLEK 241 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 GDII TGTP GV + + FL+ GD + EIE +G ++ Sbjct: 242 GDIISTGTPAGVMLNKPNAIFLKDGDKVEMEIEGLGVLNNTIK 284 >UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Rep: Blr5285 protein - Bradyrhizobium japonicum Length = 283 Score = 169 bits (411), Expect = 7e-41 Identities = 98/284 (34%), Positives = 146/284 (51%), Gaps = 8/284 (2%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXX-- 58 MKLL F + G + + VVD+ +TL +LL+ Sbjct: 1 MKLLSFIVDSRTSF--GAVKDNGVVDLGARMAGC-TTLRQLLEAGRVAEAAKLVASAAPD 57 Query: 59 XXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLK 118 L ++ + K++CVGLNY+DH E E P +F +FP + VG I +K Sbjct: 58 HALDKVSFAPVIPDPGKIICVGLNYRDHVAETGRIVTEKPALFVRFPCSQVGHLQPI-VK 116 Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGK 178 VS E EL +VIGK+ + ++ A D++ GY+ + DW+++ SQ L GK Sbjct: 117 PKVSDDFDYEGELALVIGKEGRHIPANRALDHIAGYSCYNEGSVRDWQRHT--SQFLSGK 174 Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTL 238 GPW+VT+DEI +P L ++ +NG Q + T+ I IP +IA +S + L Sbjct: 175 TFAESGSFGPWLVTADEIPDPSKLTLQTRLNGTVVQDTTTDLLITAIPGLIAYISTICPL 234 Query: 239 LPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 +PGD+I+TGTPGGVG R PP +++PGD + EI IGT +V Sbjct: 235 VPGDVIVTGTPGGVGAKRTPPLWMRPGDTVEVEISGIGTLRNKV 278 >UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase family protein; n=2; Arthrobacter|Rep: Putative fumarylacetoacetate hydrolase family protein - Arthrobacter nitroguajacolicus Length = 299 Score = 169 bits (411), Expect = 7e-41 Identities = 89/208 (42%), Positives = 122/208 (58%), Gaps = 6/208 (2%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 KV+C GLNY DH +E P+ P +F K+ T+VG +D I + S V E EL VV Sbjct: 75 KVICCGLNYGDHIQEMGRALPDYPTLFAKYADTLVGASDPIYVHG--SDKVDWEAELAVV 132 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IG +VD A + GYT+A D+ DW+ N+ + Q GKA D P+GP ++T+D Sbjct: 133 IGSNLYRVDEDQALAGIAGYTVANDVSMRDWQ-NRTL-QWFQGKAFDATTPLGPVMLTAD 190 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 E P + +V +NG Q QK NT+ + ++A +S L PGD++LTGTPGGVG+ Sbjct: 191 EA--PADFDVYGYVNGEQVQKGNTSTLVFGPARLVAYISQFTMLRPGDVVLTGTPGGVGM 248 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282 NPP FL GDV+T+EI IG E R+ Sbjct: 249 GMNPPRFLSDGDVLTTEIPGIGRLENRI 276 >UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=5; Thermoprotei|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Pyrobaculum islandicum (strain DSM 4184 / JCM 9189) Length = 310 Score = 169 bits (411), Expect = 7e-41 Identities = 86/227 (37%), Positives = 132/227 (58%), Gaps = 9/227 (3%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 I + PV +K+LCV +NY++H E + PP+ P+ F KFP+ +VG + +K V + Sbjct: 86 IKWEPPVPNPEKILCVAVNYREHGAETGIEPPDKPYFFPKFPNALVGHEGYV-VKHRVVQ 144 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK--NKKISQL----LLG 177 + E+EL VV+G+ ++ A DYV GYT+ D+ DW+ K Q + G Sbjct: 145 KLDWEVELVVVMGRPGKYIEPERALDYVFGYTVGLDMSMRDWQNPDEKTARQYGKNWIWG 204 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 K MDT P+GP+I T DE+ +P L ++ +NG +Q+ NT+Q I I +I S +T Sbjct: 205 KTMDTAAPVGPYIATRDEVPDPNRLGLRLWVNGQLEQEGNTSQLIFNIQQLIYWASQGIT 264 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 L PGD+I TGTP GVG + +FL+ GD++ +E+E+IG + E Sbjct: 265 LRPGDLIFTGTPPGVGWAKG--KFLKGGDIVEAEVESIGRLRAYIIE 309 >UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=4; Archaea|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Methanobacterium thermoautotrophicum Length = 260 Score = 168 bits (409), Expect = 1e-40 Identities = 90/223 (40%), Positives = 133/223 (59%), Gaps = 14/223 (6%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L + + PV + KV+CVGLNY+DH E + P+ P IF K P+TV+G DT+ + + Sbjct: 46 LDDVRILPPVSPS-KVVCVGLNYRDHAAELGMDIPDEPIIFLKPPTTVIGSGDTV-IYPE 103 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 +S V E+EL V+ ++A +VDSS A +++ GYT+ D+ A D ++ Q K+ Sbjct: 104 MSSEVDYEVELAAVVSERARRVDSSAASEFIAGYTVLNDVTARDLQRRD--GQWTRAKSF 161 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 DTFCPIGP I T P NL++ +NG +Q SNT+ I + +++ +S+VMTL P Sbjct: 162 DTFCPIGPVIETDV---TPDNLDISLKLNGEVRQSSNTSNMIFTVHELLEFISHVMTLEP 218 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 GD+I TGTP GVG + PGD + + +E +GT RVE Sbjct: 219 GDVIATGTPPGVGQ-------MVPGDTVRATVEGVGTLVNRVE 254 >UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Proteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Xanthobacter sp. (strain Py2) Length = 281 Score = 167 bits (407), Expect = 2e-40 Identities = 90/282 (31%), Positives = 139/282 (49%), Gaps = 6/282 (2%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX 60 MK F++ G G + ++D+ + P+ P TL + Sbjct: 1 MKFASFTHAGRAGY--GLVTDGGIIDLTRRFPEAP-TLRTFIAGGLDRAAAVAGAPADFA 57 Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 LS +TL + DK++CVGLNY DH E T P +F ++ + VG + ++ Sbjct: 58 LSEVTLAPVIPDPDKIVCVGLNYHDHVNETGRTVTPNPMLFARYAGSQVGAGTALVKPLE 117 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 S E EL V+IGK ++ + A +V GY D DW+++ SQ + GK Sbjct: 118 -SDEFDYEGELAVIIGKAGRRISEADALSHVAGYACYNDASVRDWQRHT--SQFMPGKTF 174 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 GPW+V++DEI +P L + +NG Q Q ++ + I IP +IA S ++ LLP Sbjct: 175 AATGAFGPWMVSADEIPDPTRLTLATRLNGAQVQHTSVDLMITPIPTLIAYTSTILPLLP 234 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GD+I++GTPGGVG R P F++ GDV+ E+ IG + Sbjct: 235 GDVIVSGTPGGVGARRTPKLFMKDGDVVEVEVSGIGVLRNPI 276 >UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Alkaliphilus metalliredigens QYMF|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Alkaliphilus metalliredigens QYMF Length = 298 Score = 167 bits (406), Expect = 3e-40 Identities = 82/207 (39%), Positives = 121/207 (58%), Gaps = 8/207 (3%) Query: 76 VLCVGLNYKDHCEEQK------LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 129 V+C+GLNYK H E + + PE P F K + +GP + I +++ V E+ Sbjct: 87 VICLGLNYKAHVAESQSALSAGIKMPEFPVYFTKMSTQAIGPQEAINSHPQITQEVDYEV 146 Query: 130 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 189 EL V+IGK + + D++ GYTI D+ A D ++ +Q + GK++DTF +GPW Sbjct: 147 ELAVIIGKGGTNIPPEEVQDHIFGYTILNDVSARDLQRRH--NQWVKGKSLDTFTVMGPW 204 Query: 190 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 249 I+ + I P L++ +NG +Q SNT FI IP +I+ LS +TL GD+I TGTP Sbjct: 205 IMEKETISLPVELDLYSKVNGEIRQHSNTKDFIFDIPTVISELSKGLTLEAGDVIATGTP 264 Query: 250 GGVGVYRNPPEFLQPGDVITSEIENIG 276 GVG+ NPP++L+ GDV+ IE IG Sbjct: 265 AGVGMGFNPPKYLKAGDVVECYIEKIG 291 >UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=2; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 287 Score = 167 bits (405), Expect = 4e-40 Identities = 90/230 (39%), Positives = 124/230 (53%), Gaps = 12/230 (5%) Query: 61 LSGITLKAPVH-GNDKVLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGP 111 L + L+AP+ + CVG NY H +E P P +F K P VVGP Sbjct: 59 LHDVKLEAPIPLPRRNIFCVGRNYHAHAKELSASVFKDNSANPASWPIVFTKVPECVVGP 118 Query: 112 NDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKI 171 D + L VS+ + E EL +VIG + + A +V GYTI D+ A D + + Sbjct: 119 TDDVMLPTGVSEEIDYESELAIVIGTGGRNISRAAAMQHVFGYTIINDVTARDVQMRHQ- 177 Query: 172 SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIAR 231 Q LGK+ DTFCP+GPWIVT+DE+ + V+ +NG +Q + T I IP +I Sbjct: 178 -QWDLGKSFDTFCPMGPWIVTADELDGSRT-RVRGWVNGELRQDAQTTDLIFDIPALIET 235 Query: 232 LSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETR 281 S +TL PGD+I TGT GVG+ PP++L+ GDV+ EI+ IG E R Sbjct: 236 CSRGITLYPGDVIATGTAAGVGMGMKPPQYLKAGDVVRIEIDGIGAIENR 285 >UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Polynucleobacter sp. QLW-P1DMWA-1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Polynucleobacter sp. QLW-P1DMWA-1 Length = 299 Score = 167 bits (405), Expect = 4e-40 Identities = 97/284 (34%), Positives = 146/284 (51%), Gaps = 14/284 (4%) Query: 7 SYKNSDGIRA-GFLDGDNVVDINKEDPKL----PSTLIELLKT------NXXXXXXXXXX 55 S N+DG G + V+D+ K+ P TL +LL+ N Sbjct: 9 SIMNADGTETLGVVTPKGVIDVRAVAKKMKIAAPVTLDQLLQEGNAQGFNKVVASADQSG 68 Query: 56 XXXXXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTI 115 S IT K++CVGLNY+ H +E + P +P +FNK+ +++ N + Sbjct: 69 VPYLQESNITFGRLFKSPGKIVCVGLNYRAHADEVGMVHPRVPPLFNKYNNSLAAHNCLL 128 Query: 116 KLKM-DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174 ++ VS + E EL +VIGK+ V S A DYV GY + D + D + Q Sbjct: 129 QIPPPSVSYKLDYETELLIVIGKQMRNVPESAALDYVAGYCTSNDFSSRDLQLELPSGQW 188 Query: 175 LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSN 234 ++GK +D + PIGP+ VT D +GNP NL VK +NG +Q SNT+ FIH +++ +S Sbjct: 189 MIGKTLDQYAPIGPYFVTGDLVGNPNNLQVKTWVNGELRQNSNTSDFIHNTQKMLSYIST 248 Query: 235 VMTLLPGDIILTGTPGGV--GVYRNPPEFLQPGDVITSEIENIG 276 L PGDI+ TGTP GV G+ ++ +L+ GD + S +E +G Sbjct: 249 YWALEPGDIVFTGTPQGVIAGMPKDKQVWLKKGDKVVSSVEKLG 292 >UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase; n=1; Psychroflexus torquis ATCC 700755|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase - Psychroflexus torquis ATCC 700755 Length = 251 Score = 166 bits (404), Expect = 5e-40 Identities = 85/190 (44%), Positives = 116/190 (61%), Gaps = 2/190 (1%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 I L +P+ K++CVGLNY H +E + P P +F K S +VGP D I L K Sbjct: 64 IRLGSPIDRPSKIVCVGLNYAKHAKESGMEVPTEPVLFFKASSAIVGPYDDIILPKKSEK 123 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183 + E+EL ++IG KAS V S A D+V GY I DI +++ + Q + GK+ DTF Sbjct: 124 SD-WEVELAIIIGDKASYVKESEAMDHVAGYVIHNDISEREYQLERS-GQWVKGKSCDTF 181 Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243 PIGP++VT+DEI +P NL + +NG Q SNT+ I IP +++ +S MTLLPGD+ Sbjct: 182 APIGPFMVTTDEIDDPHNLRLWLKLNGETMQDSNTSDLIFGIPKLVSYISTYMTLLPGDV 241 Query: 244 ILTGTPGGVG 253 I TGTP GVG Sbjct: 242 ISTGTPFGVG 251 >UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp. RHA1|Rep: Probable hydrolase - Rhodococcus sp. (strain RHA1) Length = 553 Score = 166 bits (404), Expect = 5e-40 Identities = 89/232 (38%), Positives = 132/232 (56%), Gaps = 15/232 (6%) Query: 63 GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP------------PELPFIFNKFPSTVVG 110 G L AP+ + V CVG NY +H E + P+ P +F K +TV+ Sbjct: 60 GGKLLAPITPHRNVFCVGRNYSEHAAEFAESGFDATGSADGQHVPQYPVVFTKPAATVIA 119 Query: 111 PNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK 170 D + D++ A+ E E+ ++IGK+ASKV A DYV GYT+ D+ A D +++ K Sbjct: 120 CGDPVDPHTDITSALDYEGEIGIIIGKRASKVSRDDAMDYVWGYTLINDVTARDLQRDHK 179 Query: 171 ISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIA 230 Q +GK++DTFCP+GPW VT+DEI + +L ++ +NG +Q +NT Q I +P II Sbjct: 180 --QWFIGKSLDTFCPLGPWAVTADEI-DINDLQLQTRVNGELRQDTNTAQLIFDVPTIIE 236 Query: 231 RLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 LS +TL PGD+I TGTP GVG+ +PP++L GD + +G + Sbjct: 237 TLSAGITLEPGDVIATGTPVGVGIGFDPPKYLVEGDEVIVSAPGLGELRNTI 288 >UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila melanogaster|Rep: CG11251-PA - Drosophila melanogaster (Fruit fly) Length = 338 Score = 166 bits (403), Expect = 6e-40 Identities = 89/219 (40%), Positives = 126/219 (57%), Gaps = 7/219 (3%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 + L P+ K++ V NY D+C+EQ ++ P P KF S++ G D I+ +K Sbjct: 122 LRLLPPIDSPSKIIGVDCNYVDNCDEQHISIPREPSFHVKFASSITGALDNIRAHSS-AK 180 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183 + +L VV+GK+ +V A ++V G+ + QDI A DW L G +MDTF Sbjct: 181 HIDYGCQLAVVMGKRCREVSPKEALNHVFGFMVVQDIVARDWNVP------LGGHSMDTF 234 Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243 P+GP IV + + NL +K ING ++Q NT I KI +I RLS +TL PGDI Sbjct: 235 LPLGPTIVHRCHVPDLNNLWIKTIINGEERQTGNTRNMIFKIDFLIHRLSQYLTLCPGDI 294 Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 ILTGTP G G +R+P FL+PGD+I SEI+N+G +V Sbjct: 295 ILTGTPAGSGAFRHPSCFLKPGDLIESEIQNLGKMCNKV 333 >UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase)/5- carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate decarboxylase; n=1; Frankia alni ACN14a|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase)/5- carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate decarboxylase - Frankia alni (strain ACN14a) Length = 276 Score = 165 bits (402), Expect = 9e-40 Identities = 87/222 (39%), Positives = 125/222 (56%), Gaps = 3/222 (1%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L G L V K++C+GLNY H +E TPP P +F K+ ++GP D I L Sbjct: 55 LDGADLAPLVPAPPKIICMGLNYATHLKEMGRTPPTHPTLFAKYTRALIGPTDDI-LVPP 113 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 V++AV E EL VIG D + A + + GYTI D+ DW+ + Q L GK+ Sbjct: 114 VTEAVDWEGELAFVIGTTVRFADEAAAREAIAGYTIMNDVTMRDWQF--RTLQFLQGKSF 171 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 + P+GP +VT DE+ NP +L ++ +NG QKS T+ + +I+ +S +TL P Sbjct: 172 EGSTPLGPALVTPDELDNPADLALRTLVNGEVMQKSRTSDLLFPPVEIVRYVSQFITLEP 231 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GD++ TGTPGGVG RNP +L GDV+T ++E +G V Sbjct: 232 GDVLTTGTPGGVGHGRNPKVYLADGDVVTVDVEGLGVVRNTV 273 >UniRef50_O53242 Cluster: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE; n=41; Bacteria|Rep: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE - Mycobacterium tuberculosis Length = 239 Score = 165 bits (401), Expect = 1e-39 Identities = 93/222 (41%), Positives = 128/222 (57%), Gaps = 11/222 (4%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L+ + L AP+ + KV+CVG NY DH E PP P IF K + ++GPN I+L + Sbjct: 23 LADVRLLAPILAS-KVVCVGKNYADHIAEMGGRPPADPVIFLKPNTAIIGPNTPIRLPAN 81 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 S V E EL +VIG+ V ++ A D +LGYTI D+ A D +++ Q K Sbjct: 82 ASP-VHFEGELAIVIGRACKDVPAAQAVDNILGYTIGNDVSARDQQQSD--GQWTRAKGH 138 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 DTFCP+GPWIVT +P +L ++ +NG KQ + T+ IH I I+ +S +MTLLP Sbjct: 139 DTFCPVGPWIVTDLAPFDPADLELRTVVNGDVKQHARTSLMIHDIGAIVEWISAIMTLLP 198 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GD+ILTGTP GVG ++ GD ++ IE IGT V Sbjct: 199 GDLILTGTPAGVGP-------IEDGDTVSITIEGIGTLTNPV 233 >UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase; n=2; Rhodococcus|Rep: Possible fumarylacetoacetate hydrolase - Rhodococcus sp. (strain RHA1) Length = 296 Score = 165 bits (401), Expect = 1e-39 Identities = 83/212 (39%), Positives = 120/212 (56%), Gaps = 4/212 (1%) Query: 66 LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125 L APV ++ +G+NY DH EE LT P+ PF+F KFP+++ GP DTI+ V Sbjct: 63 LGAPVPRPGQIFAIGVNYADHVEESGLTLPDAPFVFTKFPASITGPYDTIE---HPGGLV 119 Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLLLGKAMDTFC 184 E+EL VIGK+A V + ++YV G T+ QD+ D + Q LGK+ F Sbjct: 120 DFEVELVAVIGKEARHVPVAEGWEYVAGLTLGQDLSERDLQLSGPPPQQFTLGKSFAGFA 179 Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244 PIGP +VT DE +P ++ V ++G Q S T I IP +++ LS+++ L PGD+I Sbjct: 180 PIGPVLVTPDEFADPDDIEVSTILSGELMQNSRTRHLIFPIPVLVSYLSSILPLRPGDLI 239 Query: 245 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 TGTP G+G R+P + D + S + IG Sbjct: 240 FTGTPSGIGFTRDPKRLIGVDDELVSRADTIG 271 >UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=6; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Burkholderia cepacia (strain ATCC 53795 / AMMD) Length = 291 Score = 165 bits (401), Expect = 1e-39 Identities = 96/291 (32%), Positives = 150/291 (51%), Gaps = 12/291 (4%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX 60 MKL+ F +N D R G LDG +V+D+N+ DP +P+ L L+ Sbjct: 1 MKLITFK-QNGD-TRLGVLDGSDVIDLNRADPAVPADLRAALEAGVDVVAAARNAATRAD 58 Query: 61 ------LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT 114 LS + L V K++C+G N+ DH +E P P IF + ++++ D Sbjct: 59 VGNRIPLSEVELAPVVPKPGKIVCLGHNFYDHAKEGGNLKPVYPLIFFRGATSLIAHGDP 118 Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174 + ++ VS+ + E EL VVIGK V +A D+V GY D+ D++K + +Q Sbjct: 119 V-IRPFVSEKLDYEAELVVVIGKTGRHVKRENALDHVFGYACFNDVSVRDYQK--RTAQW 175 Query: 175 LLGKAMDTFCPIGPWIVTSDEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233 +GK D GPW+VTSDE+ L ++ +NG Q++NT I + + I L+ Sbjct: 176 TIGKNFDGTGAFGPWLVTSDELPPGAAGLKLELRLNGEAMQRANTADMIWSVAETIELLT 235 Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 +TL PGD+++ GTP GVG R PP +++ GD + +IE IG V++ Sbjct: 236 ECLTLEPGDVVVMGTPAGVGFARTPPVWMKAGDRVEVDIEGIGVLSNVVQD 286 >UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 233 Score = 164 bits (399), Expect = 2e-39 Identities = 86/198 (43%), Positives = 116/198 (58%), Gaps = 2/198 (1%) Query: 79 VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 138 V LNY D E P +PF+F K S+V+G D I + V++ V E EL VVIG + Sbjct: 19 VALNYVDSIAEMGFERPTVPFLFPKLSSSVIGDGDPIVVDTTVTRFVDWETELAVVIGTE 78 Query: 139 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 198 A V ++ A + V GYT+A DI A D Q L GK +DTFCP+G +V + EI + Sbjct: 79 ARNVPAAEALEVVYGYTVANDISARDLLTAD--GQWLRGKGLDTFCPLGHVVVPAAEIPD 136 Query: 199 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 258 PQ L V+ +NG Q T + + ++I+ LS TL PGD+ILTGTP G G + +P Sbjct: 137 PQALAVRTWLNGEIVQDGTTADMVFGVGELISYLSRFFTLRPGDVILTGTPAGCGAFMDP 196 Query: 259 PEFLQPGDVITSEIENIG 276 P L+PGDV+ SE+E IG Sbjct: 197 PRGLRPGDVVESEVEGIG 214 >UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4; Thermococcaceae|Rep: Uncharacterized protein PH0643 - Pyrococcus horikoshii Length = 230 Score = 164 bits (399), Expect = 2e-39 Identities = 94/207 (45%), Positives = 123/207 (59%), Gaps = 11/207 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++ + NY +H E PPE P IF K PS ++GP +I L SK V E+EL V+ Sbjct: 22 KIVALAKNYAEHAREMGSEPPEEPIIFLKPPSALIGPGSSIILPRR-SKRVDHEVELAVI 80 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 192 +GK+A V +S AFDY+LGYTI DI A D E KK + K DTF PIGP +V Sbjct: 81 MGKRAKNVPASKAFDYILGYTIILDITARDLQAEARKKGYPWTISKGFDTFAPIGPRVVD 140 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252 S E+ +P +L + +NG +Q T+Q I KIP++I +S++MTL PGDII TGTP GV Sbjct: 141 SREL-DPSDLEIGLKVNGKIRQLGRTSQMIFKIPELIEYISHIMTLEPGDIIATGTPPGV 199 Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFE 279 G R+ GD I + IE IG E Sbjct: 200 GPLRH-------GDRIEAWIEGIGKME 219 >UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep: Bll6360 protein - Bradyrhizobium japonicum Length = 314 Score = 164 bits (398), Expect = 3e-39 Identities = 83/210 (39%), Positives = 122/210 (58%), Gaps = 3/210 (1%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128 PV G K + +GLNY DH E L P P +F K +++ GPND + L K E Sbjct: 92 PVSGVGKFVAIGLNYADHAAEAGLPLPSEPIVFQKAITSLSGPNDAVVLPRGSLKGD-WE 150 Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188 +EL +VIG +AS V+ A YV GY + D+ +++ + GK DTF P+GP Sbjct: 151 VELGIVIGSRASYVEPVEALQYVAGYCVVNDVSEREYQMERG-GTWDKGKGCDTFGPVGP 209 Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248 W+VT+DE+ +P L++ +NG + Q+ NT + I++ +S MTL+PGDII TGT Sbjct: 210 WLVTTDEVPDPGRLDIWLELNGRRMQQGNTRTMVFGCAGIVSYVSQFMTLMPGDIIATGT 269 Query: 249 PGGVGVYRNP-PEFLQPGDVITSEIENIGT 277 P GVG+ P P +L+ GD++T I+ +GT Sbjct: 270 PPGVGMGMKPDPIYLKVGDIMTLGIQGLGT 299 >UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family protein; n=5; Pezizomycotina|Rep: Fumarylacetoacetate hydrolase family protein - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 289 Score = 162 bits (394), Expect = 8e-39 Identities = 86/221 (38%), Positives = 122/221 (55%), Gaps = 4/221 (1%) Query: 66 LKAPVHGND--KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM--DV 121 L AP+ D V C+GLNY+ H E L P+ P +F K +++ GP D I + Sbjct: 60 LLAPLARKDIRTVRCLGLNYEQHARESNLPIPKYPVLFYKPVTSIAGPRDDIPISTMAQE 119 Query: 122 SKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMD 181 + + E EL +VIGK+A V S A DYVLGY + D+ DW+ + Q LGK D Sbjct: 120 GEGLDYECELVIVIGKEAKDVPESRALDYVLGYAVGNDVSHRDWQIKRGGGQWGLGKGFD 179 Query: 182 TFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241 + P GP IV+S I +P L++ +NG Q S+T I + ++A LS TLLPG Sbjct: 180 GWAPFGPGIVSSRLIRDPNALHISTRLNGQVVQSSSTKDMIFSVAKVVAFLSQGTTLLPG 239 Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 D+I TGTP GVG+ R P +L+ GD + +E +G+ +V Sbjct: 240 DLIFTGTPQGVGMGRKPALWLKDGDQVEVSLEGVGSCVNQV 280 >UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase; n=8; Pezizomycotina|Rep: Predicted fumarylacetoacetate hydralase - Aspergillus oryzae Length = 289 Score = 162 bits (393), Expect = 1e-38 Identities = 88/222 (39%), Positives = 121/222 (54%), Gaps = 6/222 (2%) Query: 66 LKAPVHGND--KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTI---KLKMD 120 L AP+ D V C+GLNY+ H E L P+ P +F K + + GP D I + D Sbjct: 60 LLAPLAREDIATVRCLGLNYEQHARESNLPIPKYPVLFYKPITAITGPYDDIPICSMAQD 119 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 V + + E EL +VIGK+A + A DYVLGY + DI DW+ + Q LGK Sbjct: 120 V-EGLDYECELVLVIGKQAKNIPEEQALDYVLGYAVGNDISHRDWQLKRGGGQWGLGKGF 178 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 D + P GP IV++ I NP LN+ +NG Q S+T I + ++ LS TLLP Sbjct: 179 DGWAPFGPGIVSTKLIRNPNALNISTKVNGQTVQSSSTKDMIFGVAQTVSFLSQGTTLLP 238 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GD+I TGTP GVG+ R P +L GD + +E++G+ RV Sbjct: 239 GDLIFTGTPQGVGMGRKPAAWLTNGDQVEVSLEDVGSCVNRV 280 >UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3; Burkholderiales|Rep: Putative hydrolase - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 304 Score = 161 bits (392), Expect = 1e-38 Identities = 86/229 (37%), Positives = 125/229 (54%), Gaps = 9/229 (3%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP-------PELPFIFNKFPSTVVGPND 113 L + + P+ V CVG NY++H E L PE F K P+ V+G Sbjct: 76 LQAVRVLPPLPMARNVFCVGRNYREHIIEGNLARGRPANSFPEAIEFFTKAPTAVIGHGG 135 Query: 114 TIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ 173 +K ++ ++ E+EL +VIG+ + + A D+V GYTI DI A D + Q Sbjct: 136 HVKRHAGLTDSLDYEVELAIVIGRAGADIPREKALDHVFGYTIVNDITARDLQARH--GQ 193 Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233 GK++DT CP+GP +V I + NL V S+NG +Q+ NT+ I + ++A+LS Sbjct: 194 WFKGKSLDTSCPMGPVVVHRSAIPDANNLAVSLSVNGELRQQDNTSDMIFDVAAVVAQLS 253 Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 MTLLPGD+I TGTP GVG PP LQ GDV+++ +E+IGT + Sbjct: 254 AGMTLLPGDVIATGTPKGVGFALTPPRCLQVGDVVSASVEHIGTLTNEI 302 >UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 286 Score = 161 bits (392), Expect = 1e-38 Identities = 81/210 (38%), Positives = 120/210 (57%), Gaps = 2/210 (0%) Query: 76 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 135 +LCVGLNY+ H EE L PE P IF K + GP + + + D + E ELT+VI Sbjct: 70 ILCVGLNYRRHAEECNLQIPENPAIFMKPSDALAGPLEDVPIHKDCQSMLDYEGELTIVI 129 Query: 136 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVTS 193 GK V +++ DYVLGYT+ D+ A +++ +S Q K+ D FCPIGP I ++ Sbjct: 130 GKDCKNVSAANFQDYVLGYTVGNDVSARNYQLPANVSGGQFGYAKSFDKFCPIGPCIAST 189 Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 I +PQ L +NG ++Q++ T+ I+ I +I LS TL G ILTGTP GVG Sbjct: 190 KVIPDPQKLTYWTKVNGEKRQETGTDDMIYTIGQVIEHLSRGTTLRAGTAILTGTPSGVG 249 Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRVE 283 ++ P FL+ GD + ++ IG+ +++ Sbjct: 250 LFMEPKNFLKDGDEVEIYVDGIGSIINKMK 279 >UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2; Bordetella|Rep: Putative uncharacterized protein - Bordetella parapertussis Length = 294 Score = 161 bits (391), Expect = 2e-38 Identities = 102/292 (34%), Positives = 146/292 (50%), Gaps = 19/292 (6%) Query: 7 SYKNSDGIR-AGFLDG-DNVVDINKEDPKLPSTLIELLKTNXXX---XXXXXXXXXXXXL 61 S++ DG R AG + G D +VD+ + LP L L + L Sbjct: 5 SFELPDGRRHAGVMTGPDTLVDLT-DAMDLPDLLTLLQRHGQLAGDVARLAAQARHTVAL 63 Query: 62 SGITLKAPVHGNDK-VLCVGLNYKDHCEEQKLTP----------PELPFIFNKFPSTVVG 110 + + AP+ + V CVG NY +H E + P P IF+K PS+V G Sbjct: 64 DAVRVLAPLPNPPRNVFCVGKNYHEHAREFARSGFDSSAAAGAVPAAPIIFSKPPSSVSG 123 Query: 111 PNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK 170 P D I +D +V E EL VVIGK + +V GYT+ D+ T K+ Sbjct: 124 PGDAIDTALDPCDSVDYEAELAVVIGKAGRVAPDDDPWSFVFGYTLVNDV--TSRGLQKR 181 Query: 171 ISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIA 230 SQ LLGK +D +CP+GP +V++DEIG+ L + C +NG +Q + + I IP ++ Sbjct: 182 HSQWLLGKGIDGYCPMGPALVSADEIGDIGALEITCEVNGELRQSARLSDLIFDIPTLVR 241 Query: 231 RLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 + +TL PGD+I TGTP GVG+ PP++L+ GDV+ E IG E V Sbjct: 242 AIGASITLQPGDVIATGTPVGVGIGFTPPKYLRRGDVVRVRAEPIGVLENPV 293 >UniRef50_Q67K64 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Symbiobacterium thermophilum|Rep: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Symbiobacterium thermophilum Length = 254 Score = 161 bits (390), Expect = 2e-38 Identities = 89/222 (40%), Positives = 124/222 (55%), Gaps = 11/222 (4%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L + L APV + K++C+G NY+DH E PE P F K PS ++GP + I+L D Sbjct: 43 LQAVQLLAPVTPS-KIVCIGRNYRDHAAELGNAAPERPMFFLKAPSALIGPGEAIRLP-D 100 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 V E EL VVIG++ V + A YV GYTIA D+ D +K GK+ Sbjct: 101 PDATVHWEAELAVVIGRRMKDVAPADALSYVFGYTIANDVSHRDAQKADGAFGFGRGKSY 160 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 DTFCP GP +VT E +P + + + N +Q +T IH +P++++ LS +MTL+P Sbjct: 161 DTFCPCGPAVVT--EGIDPADALITLTCNEEVRQSDSTGLMIHPVPELLSYLSQIMTLMP 218 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GD++LTGTP GVG ++PGD+I I IGT V Sbjct: 219 GDLVLTGTPKGVGA-------MKPGDLIEIHIPGIGTLANPV 253 >UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium difficile|Rep: Putative hydrolase - Clostridium difficile (strain 630) Length = 294 Score = 161 bits (390), Expect = 2e-38 Identities = 87/230 (37%), Positives = 129/230 (56%), Gaps = 9/230 (3%) Query: 61 LSGITLKAPVHGNDK-VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPND 113 L + L +P+ K ++C+GLNYKDH E + + P+ P F+K ++G +D Sbjct: 67 LEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVIKNVVMPDYPIYFSKRADKIIGVDD 126 Query: 114 TIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ 173 I L D+ + + E EL V+IGK+ + A++Y+ GYTI DI ++ K Q Sbjct: 127 KISLHGDLVEKLDYESELAVIIGKEGINISKEDAYEYIFGYTIVNDI--SERALQDKHVQ 184 Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233 GK++DT +GP IV +E +P L++ +NG +Q SNT FI IP II LS Sbjct: 185 WFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSVVNGEVRQDSNTEYFIFDIPTIINDLS 244 Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 MTL PGDII TGTP GV + NP +L+ GD++ ++E IG + V+ Sbjct: 245 RGMTLKPGDIISTGTPAGVAMGMNPQVYLKHGDIVECKVEGIGVLKNIVD 294 >UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=6; Enterobacteriaceae|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Enterobacter sp. 638 Length = 287 Score = 160 bits (389), Expect = 3e-38 Identities = 100/285 (35%), Positives = 138/285 (48%), Gaps = 9/285 (3%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX 60 MKL F YK G + D VV++ + S L LL+ N Sbjct: 1 MKLASFIYKGQRSY--GIVKADGVVNLGRRLGDRFSDLKALLQGNGMAEATRYLNDAVDV 58 Query: 61 -LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM 119 L IT + +K+LCVG+NY + +E P P +F +FP + G N + LK Sbjct: 59 PLDAITFLPVIEHPEKILCVGMNYAEKRQEFDQHNPA-PTLFVRFPDSQTGHNSPV-LKP 116 Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179 S E EL V+IGK + A +V GY+ D A DW+ + GK Sbjct: 117 RHSSEFDYEGELAVIIGKGGENISRDDALRHVAGYSCYMDGSARDWQH----TWFTAGKN 172 Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 GPW+ T+DEI +P L ++ +NG Q+ NT+ IHK+ ++I +S L Sbjct: 173 WRQTGAFGPWMATADEIPDPHRLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFTRLS 232 Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 PGD+I+TG+PGGVG RNPP F+Q GD I EIENIG + E Sbjct: 233 PGDVIITGSPGGVGKKRNPPLFMQEGDRIEVEIENIGHLSNVIME 277 >UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Clostridiaceae|Rep: Fumarylacetoacetate (FAA) hydrolase - Alkaliphilus metalliredigens QYMF Length = 300 Score = 159 bits (387), Expect = 6e-38 Identities = 85/227 (37%), Positives = 130/227 (57%), Gaps = 9/227 (3%) Query: 64 ITLKAPVHGN-DKVLCVGLNYKDHCEEQKL---TPPELPF---IFNKFPSTVVGPNDTIK 116 ITL AP+ V+CVGLNY +H +E K E+P F+K + V GP + I+ Sbjct: 76 ITLGAPIDRTIHDVICVGLNYAEHIDETKKGFDENMEIPLHTVYFSKRANQVKGPGEEIE 135 Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176 +++++ E+EL V+IGK+ + A +Y+ GYTI D+ A +KN Q Sbjct: 136 SHSHLNESMDYEVELAVIIGKEGINISKEEAKEYIFGYTILNDLSARGLQKNHV--QWFR 193 Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236 GK++D F +GP IV +G P L++K +N +Q SNT + + II+ +S M Sbjct: 194 GKSLDGFTSMGPCIVHGSSVGFPLELDIKSRVNDELRQNSNTKFMMKDVSTIISEISQGM 253 Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 TLLPGD+I TGTP GVG+ PP FL+ GD + EI+++G + +++ Sbjct: 254 TLLPGDVIATGTPSGVGMGFTPPRFLKAGDTVECEIQHMGLLKNKIK 300 >UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep: Putative oxygenase - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 287 Score = 159 bits (386), Expect = 7e-38 Identities = 86/269 (31%), Positives = 132/269 (49%), Gaps = 4/269 (1%) Query: 17 GFLDGDNVVDI-NKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXXLSGITLKAPVHGNDK 75 G + G+ ++D+ + P L + L L+ TL AP+ DK Sbjct: 19 GAVVGERIIDLATPQAPTLRAALARDGVDGLAARLRQADGAAGLALADATLLAPITDPDK 78 Query: 76 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 135 +LC+GLNY+ H EE + P P F +F ++ + L+ S E EL V+I Sbjct: 79 ILCIGLNYRLHAEEAGMAIPARPSTFVRFAGSLAAQGQPV-LRPAESDQFDYEAELAVII 137 Query: 136 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 195 GK A +V + A ++V GY + DW+++ +Q GK GPW+VT+DE Sbjct: 138 GKPARRVSQARAMEHVAGYACLAENSVRDWQRHS--TQATPGKNFVRSGAFGPWLVTADE 195 Query: 196 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 255 G P+ + V +NG Q + I + +++ LS LLPGD+I TGTP GVG+ Sbjct: 196 AGAPEAMTVIGRLNGETVQHDSVANMIFTVAQLVSYLSTFAELLPGDVIATGTPAGVGMS 255 Query: 256 RNPPEFLQPGDVITSEIENIGTFETRVEE 284 R PP +L+PGDV +I +G V++ Sbjct: 256 RKPPRYLRPGDVFEVDISGVGVLRNPVDD 284 >UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=3; Alphaproteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Roseobacter sp. MED193 Length = 285 Score = 159 bits (385), Expect = 1e-37 Identities = 81/216 (37%), Positives = 114/216 (52%), Gaps = 2/216 (0%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 ++G L PV + CVGLNY DH E L PE P +FNK T GPND I Sbjct: 60 VAGKPLAPPVAQPLNIWCVGLNYSDHAAEAGLPVPEEPILFNKSTVTYCGPNDDILKSAQ 119 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 +SK + E+EL +VI K A + A D++ G+ + DI W+ + Q + GK+ Sbjct: 120 MSK-LDWEVELGIVISKPALNISRDQAMDHIAGFVLVNDISERAWQMERS-GQWVKGKSF 177 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 FCP GP + T +E + QNL + +NG + Q NT I + I++ +S L P Sbjct: 178 PNFCPTGPVLATKEEFADVQNLGMWLDVNGERMQTGNTGTMIFDVATIVSYMSEFTRLEP 237 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 GD+I TGTP GVG PP +L GD ++ I+ +G Sbjct: 238 GDLICTGTPPGVGAGMTPPVWLNEGDKVSLGIDGLG 273 >UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=5; Bacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Nocardioides sp. (strain BAA-499 / JS614) Length = 284 Score = 158 bits (384), Expect = 1e-37 Identities = 79/212 (37%), Positives = 121/212 (57%), Gaps = 3/212 (1%) Query: 66 LKAPVHGNDKVLCVGLNYKDHCEEQKL-TPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 124 L AP + + +GLNY++H E P +LP +F KF S++ GP + L Sbjct: 68 LGAPSPRPTQAIAIGLNYEEHAHETGYQVPTQLPPVFAKFASSITGPRGLVDLPP--GGH 125 Query: 125 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 184 E+E+ VIG+ A ++ A+ +V G T+ QD+ + Q L K+ F Sbjct: 126 TDWEVEVVAVIGRTAHRISPDEAWGHVAGLTVGQDLSERISQMAGPAPQFGLAKSFPGFS 185 Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244 P+GPW+VT +E+ +P +L + C+I+G Q T++ I IP IA LS V+TLLPGD++ Sbjct: 186 PMGPWLVTPEELADPDDLALGCAIDGETVQDGRTSKLIFSIPRSIAALSQVLTLLPGDVV 245 Query: 245 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 TGTP GVG+ R+P FL+PG+ + + +E IG Sbjct: 246 FTGTPDGVGLGRSPQRFLRPGETLRTWVEGIG 277 >UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus terreus NIH2624|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 274 Score = 158 bits (384), Expect = 1e-37 Identities = 81/204 (39%), Positives = 121/204 (59%), Gaps = 4/204 (1%) Query: 76 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTVV 134 V C+GLNYK+H E K+T P+ P +F K + + + I L V E+EL ++ Sbjct: 65 VRCIGLNYKEHAAEMKMTLPDAPTVFLKANTCISSAAEPIVLPSVVDHDEADYEVELAII 124 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IG++ V + A YVLGY++A D+ A + K SQ K MD FCP+GP IV+++ Sbjct: 125 IGQRCKNVSVAEAMGYVLGYSVANDVTAR--KHQGKTSQWSYAKGMDGFCPLGPCIVSAE 182 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 +I +P ++ S+NG Q ++ + I I ++++ LS TLLPG +I+TGTP G+GV Sbjct: 183 KIPDPSVFQLRTSLNGKTMQNASADDMIFSIAEVVSYLSQGHTLLPGTVIITGTPCGIGV 242 Query: 255 YRNPPEFLQPGDVI-TSEIENIGT 277 +NPP FL+PGD + S IGT Sbjct: 243 SQNPPVFLKPGDRLRISASHGIGT 266 >UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Exiguobacterium sibiricum 255-15|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Exiguobacterium sibiricum 255-15 Length = 277 Score = 158 bits (383), Expect = 2e-37 Identities = 84/222 (37%), Positives = 121/222 (54%), Gaps = 3/222 (1%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 I L AP V+CVG NY DH +E +F K PS++VGP + I+ D+++ Sbjct: 58 IRLLAPYIPPRNVICVGKNYADHIKEMDTAGAGKFVLFTKAPSSIVGPFEAIERHADLTQ 117 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183 + E EL ++IG + +A D+V GY+I D+ A D +K Q GK++D F Sbjct: 118 QLDYEGELAIIIGTSGRDLTPENALDHVFGYSIVNDVTARDLQKEHV--QFFRGKSLDGF 175 Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243 CP GP IVT D +P ++ V+ +NG +Q +T + + I+ +S MTL GDI Sbjct: 176 CPFGPVIVTEDSF-DPTDVLVETRVNGQLRQSGSTKLMLRDVVTILTEVSRGMTLEAGDI 234 Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285 I TGTP GVG PP +LQ GDV+ IE IG + V+ + Sbjct: 235 IATGTPAGVGHGMKPPTYLQDGDVVDISIEGIGHLQNHVKAY 276 >UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=2; Proteobacteria|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Fulvimarina pelagi HTCC2506 Length = 337 Score = 157 bits (382), Expect = 2e-37 Identities = 76/211 (36%), Positives = 122/211 (57%), Gaps = 2/211 (0%) Query: 66 LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125 L AP+ + +GLNY DH E P P +F+K PS++ GP+D + + +K + Sbjct: 117 LGAPIARVGHFIAIGLNYADHAAETGADLPVEPLVFSKAPSSICGPHDELPIPPGSTK-L 175 Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185 E+EL VVIG++A ++ + A ++V G+ + D+ ++K + Q + GK+ Sbjct: 176 DWEVELAVVIGERAYNINETEAMNHVAGFCLCNDVSERAFQKERG-GQFIKGKSSPRTGA 234 Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 +GPW+VT D +G+PQ L++ S+NG +Q+ T + I++ LS M L PGD+I Sbjct: 235 LGPWLVTPDRLGDPQQLDLWLSVNGEIRQRGTTRDMLFSAAFIVSYLSKFMILEPGDVIT 294 Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 TGTP GVG PP+FL+ GD++T I +G Sbjct: 295 TGTPSGVGAGMTPPQFLREGDILTLGIGGLG 325 >UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Bacillus halodurans|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus halodurans Length = 276 Score = 157 bits (380), Expect = 4e-37 Identities = 89/224 (39%), Positives = 132/224 (58%), Gaps = 13/224 (5%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKL--TPPELPFIFNKFPSTVVGPNDTIKLK 118 L+ + L+ P+ K++ +NY H +E + T L F F K ++++GPND I L Sbjct: 61 LNDVRLRQPLSRPGKIVAAPVNYMSHKKEMNVDHTARVLGF-FLKATTSIIGPNDPIILP 119 Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGK 178 + ++ + E+EL VIGK+A V +A DY+ GYT D+ KN++ + L K Sbjct: 120 YN-NRRIDHELELAFVIGKRAKHVKKENAHDYIFGYTGLNDVTVRP-TKNRE-EERCLRK 176 Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTL 238 + DTF PIGPWIVTSDEI +PQNL + +N +Q NTNQ + I +++ S+VMTL Sbjct: 177 SFDTFTPIGPWIVTSDEIKDPQNLTISLQVNHEVRQHVNTNQMVCGIAELVEIFSHVMTL 236 Query: 239 LPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 PGD+I TGTP GVG ++ GD +T ++E+IG+F V Sbjct: 237 EPGDLIATGTPDGVGP-------IKDGDTVTLQMESIGSFSNPV 273 >UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=5; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Mesorhizobium sp. (strain BNC1) Length = 287 Score = 156 bits (379), Expect = 5e-37 Identities = 91/289 (31%), Positives = 149/289 (51%), Gaps = 14/289 (4%) Query: 1 MKLLQFSYKNSDGIRA-GFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXX 59 MKL F++ G+R G ++ VVD+ +P+LP+ ++ +L+ Sbjct: 1 MKLALFTH---GGVRRIGLVERGEVVDLLSGNPRLPNDMVAILEGGAETLEAVRLAAGRA 57 Query: 60 ---XLSGITLKAPVHGNDKVLCVGLNYKDHCEEQK---LTPPELPFIFNKFPSTVVGPND 113 L+ + L AP+ K L +GL++K +E + + PE FNK + + GP D Sbjct: 58 NRLALNEVQLNAPITRPRKFLGLGLSFKSSADEFRAKGVAIPEHQVWFNKQVTAINGPYD 117 Query: 114 TIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ 173 + + VS + E EL +VIGK+ +S A + G+ + D DW++ + Sbjct: 118 PVHMPR-VSSELDYEGELALVIGKRIRHARTSDAEKIIAGFLVCNDFSVRDWQRRSPTAT 176 Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233 L GK+ DT PIGPW+ T DE+ +P +L ++ ++G +Q NT+ ++ ++IA LS Sbjct: 177 L--GKSFDTHGPIGPWLTTFDEV-DPSSLRIRTWVDGELRQDGNTDDLLYTFGEMIAELS 233 Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TL PGDI+ TG+P G G Y PP +L+ G + EIE +G E + Sbjct: 234 TAFTLEPGDILATGSPTGAGQYMRPPTYLKTGQTVRVEIEGLGHIENMI 282 >UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 282 Score = 156 bits (379), Expect = 5e-37 Identities = 87/216 (40%), Positives = 117/216 (54%), Gaps = 4/216 (1%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L + L P+ DKVLCV N+++ E K PE P +F +F ++ G + K D Sbjct: 58 LDQVRLLPPIPNPDKVLCVATNFREPAREGK-PEPEYPLVFTRFANSFTGHGQPLA-KPD 115 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 S+A E EL VVIGK ++ +S A +V GY D DW+K+ +Q GK Sbjct: 116 RSEAYDFEGELAVVIGKGGHRIPASEAMAHVGGYCCLNDGSVRDWQKHS--TQFTPGKNF 173 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 GPWIVT+DEI +P L ++ +NGV KQ+ ++ I IP +IA S L+P Sbjct: 174 HRSGSFGPWIVTADEIPDPTVLTLQTRVNGVVKQRIGIDRMIFDIPWLIAYFSTFTPLVP 233 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 GD+I TGTP G G R PPE+L GD I EI IG Sbjct: 234 GDVIATGTPSGFGSSRTPPEYLSIGDAIEVEISEIG 269 >UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG11179.1 - Gibberella zeae PH-1 Length = 281 Score = 155 bits (377), Expect = 9e-37 Identities = 87/225 (38%), Positives = 123/225 (54%), Gaps = 8/225 (3%) Query: 66 LKAPVHGND--KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 L P+ ND V+C+GLNY DH EE ++ P++P +F K + + GP+D + L + Sbjct: 54 LLCPIDLNDARSVVCIGLNYTDHAEEAQMPIPKVPVVFFKPVTALAGPHDDLVLPHTSWE 113 Query: 124 A--VVCEIELTVVIGKKASKVDSSHAFDYVLGYTI--AQDIGATDWEKNKKIS--QLLLG 177 + E EL +VIGKKAS+V A DYV YT DI W+ + ++ Q Sbjct: 114 KGRLDYESELVIVIGKKASRVSKDDALDYVFSYTFHAGNDISNRAWQLDPQLGGGQWCYS 173 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 K D PIGP IV+ D +G+ L ++ ++N Q Q NTN I + +I++ LS MT Sbjct: 174 KCFDCSAPIGPAIVSKDILGSAVGLGIRGTLNDTQSQDGNTNNMIFGVAEIVSFLSQGMT 233 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 LLPG I TGTP GVG + P ++ GDV EI+ IG +V Sbjct: 234 LLPGTFIFTGTPAGVGFGKKPQISVKEGDVTQVEIDGIGAIVNKV 278 >UniRef50_Q88Y59 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioateisomerase / 5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioatedecarboxylase; n=1; Lactobacillus plantarum|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioateisomerase / 5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioatedecarboxylase - Lactobacillus plantarum Length = 276 Score = 155 bits (375), Expect = 2e-36 Identities = 76/218 (34%), Positives = 120/218 (55%), Gaps = 3/218 (1%) Query: 66 LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125 L AP+ ++ VG+NY+DH E +T P++P IF KF S++ N T+ Sbjct: 62 LAAPITAPRQIFAVGMNYRDHSAEIHITLPKVPSIFTKFSSSLAPANVTMATH---GPET 118 Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185 E EL V+IGK + ++ A +V G + +D+ + Q +GK+ + + P Sbjct: 119 DWETELVVMIGKGGRDIATADAMAHVAGVMVGEDLSDRAVQFENDNPQFSIGKSFENYAP 178 Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 +GPW+ T DE+ N + + ++NG Q++ +Q I K+PD++ LS V L PGD+I Sbjct: 179 VGPWLTTVDELANLDDEVITTTVNGQTMQQAPLSQLIFKVPDLVHYLSTVCELQPGDLIF 238 Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 TGTP G GV RNP FLQ GD + +I ++GT ++ Sbjct: 239 TGTPSGTGVGRNPQVFLQAGDQLCGQITHLGTLNITIK 276 >UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia farcinica|Rep: Putative hydrolase - Nocardia farcinica Length = 285 Score = 155 bits (375), Expect = 2e-36 Identities = 80/209 (38%), Positives = 116/209 (55%), Gaps = 3/209 (1%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTV 133 K++C G NY+ H E PE P +F KF T+ + I L M + A + E EL V Sbjct: 62 KIVCCGHNYRAHIAELGRAEPEFPTLFAKFADTLTAWDADITLGMAAADAGLDWEAELAV 121 Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193 V+G + + D + A + GYT+A D W++ + +Q L GKA D P+GP +VT Sbjct: 122 VVGAELRRADRATARAGIAGYTVANDFSVRTWQR--RTAQWLQGKAFDATTPLGPDLVTP 179 Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 DE L + C +NGV +Q +T+ + +++ +S TL PGD++LTGTPGGVG Sbjct: 180 DEADPGDGLRITCRVNGVVEQCGSTDDLLFDPAALLSYISAFTTLRPGDVVLTGTPGGVG 239 Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRV 282 V +PP L GDV+ +EIE IG R+ Sbjct: 240 VAADPPRHLGDGDVVETEIEGIGLLRNRI 268 >UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase; n=1; Cenarchaeum symbiosum|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase - Cenarchaeum symbiosum Length = 288 Score = 154 bits (373), Expect = 3e-36 Identities = 83/222 (37%), Positives = 122/222 (54%), Gaps = 3/222 (1%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 LS + AP+ K+ C+ NY DH ++Q +PP+ P I K + + G D I + Sbjct: 65 LSEYGIMAPIAEPPKIFCLAFNYADHAQDQDRSPPDEPVIVMKPRTALCGNGDDIVMPPF 124 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 V K + E+EL ++IGK+ VD A + + GYTI D+ A D + Q K + Sbjct: 125 V-KELDYEVELALIIGKRCRDVDVIGAKEAIFGYTILNDVSARDIQFRD--GQFTRAKGL 181 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 DTF P GPWI ++DE+ +P L + +NG +Q S+T++ K +I+++LS+ MTL Sbjct: 182 DTFAPCGPWITSADEVQDPGRLKMTTKVNGRARQDSSTSKMHIKPFEIVSKLSSSMTLEK 241 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GDII TGTP GV + E+L GD I EIE +G V Sbjct: 242 GDIISTGTPSGVALNNPDSEYLAAGDEIEMEIEGLGVLRNTV 283 >UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Desulfitobacterium hafniense|Rep: Fumarylacetoacetate (FAA) hydrolase - Desulfitobacterium hafniense (strain DCB-2) Length = 251 Score = 153 bits (372), Expect = 4e-36 Identities = 89/219 (40%), Positives = 123/219 (56%), Gaps = 14/219 (6%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 + L APV K++C+GLNY H EE + P IF K +++VGP D I L +S+ Sbjct: 46 VRLLAPVEPT-KIVCIGLNYAKHIEELGHDFHDDPVIFLKPVTSLVGPEDEIILPA-MSQ 103 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183 V E EL VVIGK A + A DY+ G+T D+ A D +K K Q K DTF Sbjct: 104 QVDYEAELVVVIGKTAKDLAEDQAEDYIFGFTCGNDVTARDLQK--KDGQWTRSKGFDTF 161 Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243 CPIGPWIV + +N+ ++ +NG KQ S T+ IH +P +++ +S +MTL PGD+ Sbjct: 162 CPIGPWIVRDLDY---RNVKIRSVLNGEVKQSSQTSHLIHSVPKLVSYISKIMTLNPGDL 218 Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 I+TGTP GVG ++ GD I +I+ IG V Sbjct: 219 IMTGTPEGVGP-------MKTGDAIAIDIKGIGRLHNLV 250 >UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase; n=1; Thermoplasma acidophilum|Rep: Probable 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase - Thermoplasma acidophilum Length = 315 Score = 153 bits (372), Expect = 4e-36 Identities = 88/217 (40%), Positives = 124/217 (57%), Gaps = 10/217 (4%) Query: 68 APVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 127 APV + K+LC+G+NY +H +E + E P IF KF +++G D I + D +K + Sbjct: 106 APVLRSGKILCIGVNYMEHAKESRQKVMEHPTIFCKFQDSIIGNMDDITVPKD-AKQIDY 164 Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187 E EL V+IG+ + +SS + GYTI D+ A D + + SQ LLGKA+ TF PIG Sbjct: 165 EGELVVIIGRSSGTAESS-----IFGYTIGNDVSARDLQF--RTSQWLLGKALPTFAPIG 217 Query: 188 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247 P IV +E+G ++L + +NG +Q NT+ I + I+ LS L PGDII TG Sbjct: 218 PVIVGKNELGFARDLQIITRVNGTVRQNGNTSDMIFDVRAIVDYLSGYFNLGPGDIIFTG 277 Query: 248 TPGGV--GVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TP GV G+ N +L+ GDVI I IGT R+ Sbjct: 278 TPEGVILGLPENERVWLKHGDVIDVSITGIGTLTNRI 314 >UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=7; cellular organisms|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Methanococcus maripaludis Length = 202 Score = 153 bits (372), Expect = 4e-36 Identities = 86/209 (41%), Positives = 121/209 (57%), Gaps = 13/209 (6%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++C GLNYKDH EE K+ P+ P IF K S+++ + IK+ S+ V E EL +V Sbjct: 7 KIVCAGLNYKDHAEELKMKLPKEPVIFLKPTSSIIYNEEAIKIPK-ASERVDYEAELAIV 65 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IGK V +Y+ G+TI D+ A D ++ K Q K+ DTF PIGP IV+ Sbjct: 66 IGKTCKSVKKEDVKNYIKGFTILNDVTARDLQE--KDGQWTRAKSFDTFSPIGPKIVSGI 123 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 + N L ++ +NG KQ SNTN I + +++ +S++MTL PGDII TGTP G+G Sbjct: 124 DANN---LKIQLRVNGKIKQDSNTNNMIFSVEELVEFVSSIMTLYPGDIISTGTPPGIGK 180 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRVE 283 L+ GD++ EIENIG + VE Sbjct: 181 -------LEKGDIVEIEIENIGILKNFVE 202 >UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Methylobacterium sp. 4-46|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Methylobacterium sp. 4-46 Length = 480 Score = 152 bits (369), Expect = 9e-36 Identities = 78/213 (36%), Positives = 118/213 (55%), Gaps = 6/213 (2%) Query: 74 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133 +K++ +G NY+ H E P+ P +FNK+ + + TIKL V++ E+EL + Sbjct: 269 EKIIMMGFNYRHHAAETGTPIPKDPPLFNKYNNALNHHGGTIKLPTAVAREFDYEVELVI 328 Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193 V G++ S V + A D V GY D A D + SQ ++GK D F P+GP++VTS Sbjct: 329 VFGRECSNVSEAEALDCVAGYATGNDFSARDLQT--LTSQFMIGKTADGFAPLGPYLVTS 386 Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 D + +P NL ++ +NGVQ+Q NTN I +I+ S +MT+ PGDI TGTP GV Sbjct: 387 DLVKDPNNLRLETRVNGVQRQDWNTNDMIFNCRQLISFASKMMTIKPGDIFYTGTPHGVI 446 Query: 254 VYRNPP----EFLQPGDVITSEIENIGTFETRV 282 P ++L+PGD + +E +G R+ Sbjct: 447 FGEKKPRAERQWLKPGDEVACSLEGLGELRFRL 479 >UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep: Lmo2266 protein - Listeria monocytogenes Length = 282 Score = 152 bits (368), Expect = 1e-35 Identities = 92/287 (32%), Positives = 148/287 (51%), Gaps = 9/287 (3%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDN-VVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXX 59 MK L + Y+ + G L +N ++ P+TL++ +K Sbjct: 1 MKWLSYLYEGD--LAYGILTPENKIIPAGTIFSNPPATLLDFIKEKPLVPELTGIDGHID 58 Query: 60 XLSGITLKAPVHGNDKVLCVGLNYKDHCEEQ--KLTPPELPFIFNKFPSTVVGPNDTIKL 117 L+ + ++ P + ++ +G NY +H E K PE +F K ++++ N I+L Sbjct: 59 -LAEVEIQVPFVPPNNIIAIGKNYYNHVLEMGSKEDVPEHILVFTKSANSLLPHNGNIEL 117 Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177 +++ + E EL V+IG+K + A + G+TI DI A D +K K Q LG Sbjct: 118 HQNITGQLDYEGELAVIIGEKVRDISEQEALSAIFGFTILNDITARDLQKKHK--QFYLG 175 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 K++D CPIGP+++ ++ P +++ +NG +Q +T++FI + II+ LS T Sbjct: 176 KSLDASCPIGPFVLENNANKEPV-FHIETKVNGEVRQSDSTDKFIFGLARIISDLSKGHT 234 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 LLPGDII TGTP GVG PP FLQ GD+I I+ IGT +V + Sbjct: 235 LLPGDIIATGTPSGVGNGMTPPTFLQDGDIIEITIDKIGTLTNKVRK 281 >UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=4; Bacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Delftia acidovorans SPH-1 Length = 309 Score = 151 bits (366), Expect = 2e-35 Identities = 79/219 (36%), Positives = 117/219 (53%), Gaps = 4/219 (1%) Query: 65 TLKAPVHGND-KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 T PV N K++CVGLNYK H E + E P +F +F ++ D + L+ S+ Sbjct: 87 TQALPVIPNPGKLICVGLNYKTHVAETRRADSEHPSLFLRFNDSLAADGDEL-LRPAFSE 145 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183 E EL VIG+ + AFD++ GY D+ DW+++ Q GK Sbjct: 146 RFDWEGELAFVIGRGGRHIAKEDAFDHIAGYACFNDVSVRDWQRHTH--QFTPGKNFPGT 203 Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243 P GPW+VT DE+ + ++L ++ +NG Q+++ I IP I+A +S L PGD+ Sbjct: 204 APFGPWLVTRDEVADVRSLALQTRLNGSVMQQASLGDLIFDIPTIVAYVSRFTPLSPGDV 263 Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 I TGTPGGVG R PP +++ GDV+ EI +G R+ Sbjct: 264 IATGTPGGVGDRREPPLYMKHGDVVEVEITGLGVLRNRI 302 >UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 356 Score = 151 bits (365), Expect = 3e-35 Identities = 80/221 (36%), Positives = 119/221 (53%), Gaps = 3/221 (1%) Query: 62 SGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV 121 S +T PV DK++ VG NY+ H E P+ P +F +FPS+ VG + + + Sbjct: 127 SSLTFLPPVTDPDKIIAVGFNYRGHLIETGTPLPDYPSLFVRFPSSQVGHGQPV-VAPSL 185 Query: 122 SKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMD 181 S E EL V+IG+ A +V + A D+V+GY+ + D++ + + Q+ GK Sbjct: 186 SGEFDFEGELAVIIGRPAWRVAEADAMDHVVGYSCFAENSVRDYQAHAR--QVTAGKNFL 243 Query: 182 TFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241 IGPW+ T+DE+G+P L + +NG Q+ I IP +IA ++ LLPG Sbjct: 244 ASGAIGPWLTTADEVGDPSTLELTTRLNGAVVQQDRLTSLIFTIPQLIAYITRFTRLLPG 303 Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 DII TGTP GVG R+P +L PGDV+ +I +G V Sbjct: 304 DIISTGTPDGVGFLRDPKIWLAPGDVLEIDIPRVGLLRNAV 344 >UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358; n=1; Citrobacter koseri ATCC BAA-895|Rep: hypothetical protein CKO_03358 - Citrobacter koseri ATCC BAA-895 Length = 295 Score = 150 bits (364), Expect = 3e-35 Identities = 95/285 (33%), Positives = 136/285 (47%), Gaps = 9/285 (3%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXX-XXX 59 MKL F Y+ + G + V+D+ L LL+ + Sbjct: 9 MKLASFLYQGTRSY--GIVTAGGVIDLGNRIGDQYRDLKALLQGDGLEQARRFAQAPVDL 66 Query: 60 XLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM 119 + IT + +K+LCVG+NY + +E P P +F +F + G N + LK Sbjct: 67 KMDAITFLPVIERPEKILCVGMNYAEKRQEFDQHDPA-PTLFVRFADSQTGHNMPV-LKP 124 Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179 S E EL V+IG + HA D+V GY+ D A DW+ S GK Sbjct: 125 RHSHEFDYEGELAVIIGNGGENISRDHALDHVAGYSCYMDGSARDWQH----SWFTAGKN 180 Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 GPW+VT+DEI +P L ++ +NG Q+ NT+ IHK+ ++I +S L Sbjct: 181 WRQTGAFGPWMVTADEIPDPHQLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFTRLN 240 Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 GD+I+TG+PGGVG RNPP F+Q GD I EIE+IG + E Sbjct: 241 SGDVIITGSPGGVGKKRNPPLFMQEGDRIEVEIEHIGHLSNVIME 285 >UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Oceanicola batsensis HTCC2597|Rep: Fumarylacetoacetate hydrolase family protein - Oceanicola batsensis HTCC2597 Length = 252 Score = 150 bits (364), Expect = 3e-35 Identities = 90/222 (40%), Positives = 121/222 (54%), Gaps = 14/222 (6%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 LS + L PV K++CVGLNYK H EE PE P +F PS V+ TI L Sbjct: 42 LSDVALLPPVEPG-KLVCVGLNYKRHAEESGAAIPEEPMLFMCAPSAVIPDGGTILLDSQ 100 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 ++ + E E+ +VIGK+A + + A + GYTI D+ D++K K Q K+ Sbjct: 101 DAR-IDYEAEIAIVIGKQARNLPEADARSCIFGYTICNDVSNRDYQK--KDGQFTRAKSF 157 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 DT+ P+GPWI T + P N + NG +Q+SNT+ I I I+A +S +MTL P Sbjct: 158 DTYKPLGPWIETGLD---PDNAAISLRQNGELRQQSNTSDMIFSIDRIVAFVSGIMTLNP 214 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GD+I+TGTP GVG R+ GD I EIE IGT V Sbjct: 215 GDVIITGTPEGVGPMRS-------GDRIEIEIEGIGTLANSV 249 >UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Hyphomonas neptunium ATCC 15444|Rep: Fumarylacetoacetate hydrolase family protein - Hyphomonas neptunium (strain ATCC 15444) Length = 277 Score = 150 bits (363), Expect = 5e-35 Identities = 84/226 (37%), Positives = 119/226 (52%), Gaps = 7/226 (3%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQ----KLTPPELPFIFNKFPSTVVGPNDTIK 116 LS + L APV K+L +G+NY H E PE+ FNK + V GP D + Sbjct: 45 LSVVRLLAPVPRPRKILGIGVNYAAHAAESVSFINTAKPEVQKWFNKQATAVNGPYDPVH 104 Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176 L VS + E EL VIGK V + A + V G+ I D DW+K + +++ Sbjct: 105 LPR-VSSQLDYEGELVAVIGKHGRHVPAERAMEIVAGFCIGCDYSVRDWQKASQT--MIM 161 Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236 GK DT P GP +VT DE+G+ +L ++ +NG +Q IH + IA L+ Sbjct: 162 GKGFDTHAPFGPALVTPDELGDISDLEIRSFVNGELRQSGRPRDMIHDVGAQIAHLTAAF 221 Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TL PGD+I TGTP GVG +PP++L+ GD + EI+ +G E + Sbjct: 222 TLEPGDVIFTGTPAGVGAGFDPPKWLKAGDRVRIEIDRLGHIENAI 267 >UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase; n=1; Methanopyrus kandleri|Rep: 2-keto-4-pentenoate hydratase hydratase - Methanopyrus kandleri Length = 264 Score = 150 bits (363), Expect = 5e-35 Identities = 88/219 (40%), Positives = 126/219 (57%), Gaps = 16/219 (7%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQK---LTPPELPFIFNKFPSTVVGPNDTIKL 117 LS + + PV K++C GLNY++H EE + + P P + K P+ V+G DT+KL Sbjct: 51 LSELRIGPPVPRPPKIICFGLNYREHVEELREMGMDVPSEPVMTMKAPTAVIGHLDTVKL 110 Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177 + ++ V E+EL VVIG++ KV A D VLG+TI D+ A D EK + Q + Sbjct: 111 PRE-ARRVDHELELAVVIGERCRKVSPEEARDAVLGFTIINDVTARDIEKRE--GQWVRA 167 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 K+ DTF P+GPWI T E P L ++ +NG +Q++ T+ + ++++ S VMT Sbjct: 168 KSYDTFAPLGPWIETELE---PDGLEMELRVNGEVRQRATTDDMVRDPYELVSFTSRVMT 224 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 L PGDII TGTP GVG ++P D I EIE IG Sbjct: 225 LEPGDIIATGTPPGVGP-------MEPDDKIELEIERIG 256 >UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4; Pezizomycotina|Rep: RIB40 genomic DNA, SC138 - Aspergillus oryzae Length = 582 Score = 149 bits (362), Expect = 6e-35 Identities = 85/231 (36%), Positives = 127/231 (54%), Gaps = 14/231 (6%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEE---------QKLTPPELPFIFNKFPSTVVGP 111 LS + P+ G D VL VG NY +H +E K P P IF K ++++GP Sbjct: 66 LSSVKHLPPISGRD-VLAVGKNYVEHAKEFNASGYDASDKSDQPTHPVIFTKRATSIIGP 124 Query: 112 NDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKI 171 + I L + V E E+ V+IGK ++ +A D+V GYTI D+ A + +++ K Sbjct: 125 EEPILLHPKFTSTVDYEGEIGVIIGKPGFQISEENASDHVWGYTIVNDMTARERQRDHK- 183 Query: 172 SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIAR 231 Q LGK+ DTFCP+GP V + + P+NL ++ +N +Q+++ + I IP +IA Sbjct: 184 -QFFLGKSPDTFCPMGPVAVPKESL--PENLKIQTFVNQELRQEASLSDLIFSIPTLIAT 240 Query: 232 LSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 +S TL GD+I TGTP GVG P +FLQ GD I+ + +GT R+ Sbjct: 241 ISAGQTLQTGDVIATGTPAGVGFGFRPMKFLQTGDEISVSVTGLGTLTNRM 291 >UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Burkholderiaceae|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 306 Score = 149 bits (360), Expect = 1e-34 Identities = 87/226 (38%), Positives = 125/226 (55%), Gaps = 11/226 (4%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQ--KLTPPE--LPFIFNKFPSTVVGPNDTIK 116 L+G L+ P + ++ NY +H E +L P E P++F K ++VV P Sbjct: 79 LAGYRLRVP-YAPRRIFAAASNYYEHAREMGTELAPREESTPYMFMKAETSVV-PTLAEV 136 Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS---Q 173 + ++ V E+EL VVIGK + + AFDYV GYTI D+ A D + Sbjct: 137 VMPPHAERVDWEVELAVVIGKPGRHIAVADAFDYVAGYTILNDVSARDLNRRTDYPFKHD 196 Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233 GK+ DTF P+GPW+V I PQNL ++ ++NG Q NT + I I + I LS Sbjct: 197 WFRGKSFDTFGPLGPWLVPRACIAEPQNLRMRLAVNGEMMQDGNTGEMIFSIAEQIHYLS 256 Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFE 279 +++TL PGD+I TGTP GVG+ R +LQPGDV+ + I+ IG+ E Sbjct: 257 SILTLQPGDLIATGTPTGVGMGRG--IYLQPGDVMVASIDGIGSIE 300 >UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3; cellular organisms|Rep: Uncharacterized protein AF_2225 - Archaeoglobus fulgidus Length = 250 Score = 148 bits (358), Expect = 2e-34 Identities = 85/202 (42%), Positives = 118/202 (58%), Gaps = 13/202 (6%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++ VGLNY DH EE + PE P +F K + V+G +D I L +S+ V E EL VV Sbjct: 45 KIIAVGLNYIDHAEELNMPVPEEPILFMKPSTAVIGHDDCIILPQ-ISQRVDYEGELAVV 103 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 I + V ++A DY+LGYT D+ A D + K Q K+ DTF P+GP+I Sbjct: 104 IAEDCRNVPETNAADYILGYTCFNDVTARDLQA--KDGQWTRAKSFDTFAPLGPYIA--- 158 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 EI +P L ++ +NG QKSNT+ I + +++ +S+VMTL GD+I TGTP GVG+ Sbjct: 159 EIDDPSKLGIQTRVNGKVVQKSNTSNLIFDVFQLVSFVSSVMTLKAGDVIATGTPAGVGM 218 Query: 255 YRNPPEFLQPGDVITSEIENIG 276 L+ GDV+ EIE IG Sbjct: 219 -------LKDGDVVEVEIEKIG 233 >UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Clostridium beijerinckii NCIMB 8052 Length = 294 Score = 147 bits (355), Expect = 4e-34 Identities = 86/231 (37%), Positives = 122/231 (52%), Gaps = 10/231 (4%) Query: 61 LSGITLKAPV-HGNDKVLCVGLNYKDHCEEQKLTPPEL-----PFI--FNKFPSTVVGPN 112 + I+ P+ + N ++C+G+NY +H E E P+ F+K +T Sbjct: 66 IENISKMPPIPNPNQDIICLGINYMEHAVESARYKNEAFGGDRPYAVYFSKRVNTATADG 125 Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS 172 D I + ++ E EL V+IGK A V AFDYV GYTI D+ A + + K Sbjct: 126 DYIPSYPQIVDSLDYEAELAVIIGKDAKDVPKEKAFDYVFGYTIINDVSARNLQTRHK-- 183 Query: 173 QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 232 Q GK++D F P+GP IVT +E NP L + +NG +Q S T+ I I D+I L Sbjct: 184 QWYFGKSLDGFTPMGPCIVTKNEFVNPPVLRICSRVNGELRQNSTTDLMITSIQDVIHEL 243 Query: 233 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 S +TL G II GTP GVG+ PP+FL+ GD++ EIE IG + V+ Sbjct: 244 SQGITLKVGTIIAMGTPAGVGMGFIPPKFLKTGDIVECEIEGIGCLKNIVK 294 >UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584; n=2; Vibrio|Rep: Putative uncharacterized protein VV1584 - Vibrio vulnificus (strain YJ016) Length = 259 Score = 146 bits (354), Expect = 6e-34 Identities = 80/218 (36%), Positives = 116/218 (53%), Gaps = 9/218 (4%) Query: 65 TLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 124 T +P+ + +GLNY DH E PP+ P +F K +T+ D+ + Sbjct: 37 TWLSPIENPGTIFALGLNYADHASELAFEPPKEPLVFLKGANTLTAHQQPSYRPNDI-EF 95 Query: 125 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 184 + E EL V+GK+A V A DY+ G+TI D D+ +N L + K+ D+ C Sbjct: 96 MHYECELVAVVGKEARNVKREDAMDYIQGFTICNDYAIRDYLENYYRPNLRV-KSRDSLC 154 Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244 PIGPWIV D+I + NL + +NG Q+ NT+ I +P +I LS+ MTL PGD+I Sbjct: 155 PIGPWIVDCDDIEDVNNLALTTHVNGELTQQGNTSDMIFDVPFLIEYLSSFMTLKPGDLI 214 Query: 245 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TGTP G+ + +QPGDV+ IE +G+ E V Sbjct: 215 ATGTPKGL-------KDIQPGDVVRCTIEGVGSLENPV 245 >UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Rhodobacterales bacterium HTCC2654|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Rhodobacterales bacterium HTCC2654 Length = 279 Score = 146 bits (354), Expect = 6e-34 Identities = 83/223 (37%), Positives = 118/223 (52%), Gaps = 7/223 (3%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQK----LTPPELPFIFNKFPSTVVGPNDTIK 116 L+G+T V +VLC+GLNYKDH E K T P+ P +F +F +++ +++ Sbjct: 54 LAGVTYTPVVPDAQQVLCIGLNYKDHRAETKGEVGTTYPDNPIVFMRFATSLAAHGESLP 113 Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176 + VS+ V E EL V+IGK + + A +V GY DI DW+ K Q Sbjct: 114 IPK-VSEVVDYEAELAVIIGKGGRYIAKADAMSHVAGYAPFNDISMRDWQM--KGEQWGP 170 Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236 GK P GP +VT DE+G+ ++ ++G Q+S I IP +I+ SN + Sbjct: 171 GKNFPKSGPFGPVMVTPDEVGDLGETGIRLILDGEVLQESWIKHLIFDIPTLISYCSNFV 230 Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFE 279 L PGD+I+TGTPGGVG R PP L PG E++ IG E Sbjct: 231 ELRPGDVIVTGTPGGVGFVRKPPILLAPGKTCVVEVDGIGRLE 273 >UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase / 5-carboxymeth..; n=42; Bacteria|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase / 5-carboxymeth.. - Yersinia pseudotuberculosis Length = 254 Score = 146 bits (353), Expect = 7e-34 Identities = 81/207 (39%), Positives = 114/207 (55%), Gaps = 9/207 (4%) Query: 76 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 135 + +GLNY DH E +PP+ P IF K P + G + ++ D + + E EL VV+ Sbjct: 46 LFALGLNYVDHAAELDFSPPKEPLIFIKAPHSFTGHRQ-VSVRPDNIEYMHYEAELVVVV 104 Query: 136 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 195 GK A ++ +HA DYV GYT+ D D+ +N L + K+ DT PIGPWIV + Sbjct: 105 GKPARYLNPAHAMDYVAGYTLCNDYAVRDYLENYYRPNLRV-KSRDTLTPIGPWIVDKAD 163 Query: 196 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 255 I NP NL ++ +NG Q+ NT I IP ++A LS +TL PGD+I TGTP G+ Sbjct: 164 IPNPHNLVIRTWVNGELCQRGNTADLIFDIPFLMAYLSEFITLQPGDMIATGTPKGL--- 220 Query: 256 RNPPEFLQPGDVITSEIENIGTFETRV 282 + PGD + E++ IG RV Sbjct: 221 ----SNVVPGDEVVVEVDGIGCLLNRV 243 >UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Polynucleobacter sp. QLW-P1DMWA-1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Polynucleobacter sp. QLW-P1DMWA-1 Length = 309 Score = 145 bits (352), Expect = 1e-33 Identities = 88/230 (38%), Positives = 122/230 (53%), Gaps = 10/230 (4%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP-----PELPFIFNKFPSTVVGPNDTIKLK 118 IT P+ DK LCVG NY+ H EE K T P+ P F K S + G N T+ Sbjct: 81 ITYLPPIMDADKFLCVGKNYRTHLEELKRTNLIKEIPQEPTSFIKLNSCLSGHNATVVRP 140 Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLL 176 ++K + E EL V+GK+A S A DY+ G TI D+ D + + S + Sbjct: 141 KGITK-LDYEPELVFVMGKRALGAKKSEAMDYIGGVTILNDLTCRDLQLREVASGSRFWT 199 Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236 GK + F P+GP I+T DEI NP +L + CS+NG ++ + NT I KI DI+ S + Sbjct: 200 GKNIPGFGPLGPEIITIDEIPNPYDLWMTCSVNGEERMRVNTQDQIWKISDILEHFSRFI 259 Query: 237 TLLPGDIILTGTPGGVGVYRNPPE--FLQPGDVITSEIENIGTFETRVEE 284 + GD+ TG PGGV V + E +L+PGDV+ I+ I T T + E Sbjct: 260 PIEAGDMFSTGAPGGVAVGKENAEALYLKPGDVVECAIDGISTLRTTIAE 309 >UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Lawsonia intracellularis PHE/MN1-00|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Lawsonia intracellularis (strain PHE/MN1-00) Length = 257 Score = 145 bits (351), Expect = 1e-33 Identities = 82/217 (37%), Positives = 122/217 (56%), Gaps = 12/217 (5%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128 P+ K++C+ +NY + +E + P P F K PS++VG I L ++ + VV E Sbjct: 45 PLVSPTKIICIDINYHEKAQELQQPIPTNPTFFFKPPSSIVGNGQPILLPTNIGR-VVSE 103 Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188 EL +VIG+ KV A +Y+ GYT A DI A D ++ + + KA +TFCP+GP Sbjct: 104 AELCIVIGQTCYKVTPEAASNYIFGYTCANDITAKDIQQQEYTTSH--AKAYNTFCPVGP 161 Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248 WI T ++ N +NL ++ SIN Q S T I ++I+ LSN+MTL PGD+ILTGT Sbjct: 162 WIET--DVPNIENLQIRNSINSELGQVSTTADMIFPPLELISFLSNIMTLNPGDLILTGT 219 Query: 249 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285 P G + GD++ + IEN+G +EE+ Sbjct: 220 PKG-------SLLISDGDIVQTSIENVGILINPIEEY 249 >UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=6; Proteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 292 Score = 144 bits (350), Expect = 2e-33 Identities = 95/294 (32%), Positives = 140/294 (47%), Gaps = 13/294 (4%) Query: 1 MKLLQFSYKNSD--GIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXX 58 MKL+ F +S G G VVD+++ P +PS LL Sbjct: 1 MKLVTFRTSDSVSWGAVVGHDSASGVVDLSRRLPDVPSVK-SLLSGGASLLARAREALAG 59 Query: 59 XX----LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP--PELPFIFNKFPSTVVGPN 112 LS + L PV G +K+ C+G+NY E K P+ P +F + P+++ G Sbjct: 60 VQVDHPLSSVQLLPPVLGPEKIFCIGVNYAHRNAEYKDNSDLPKYPSVFMRTPASLTGHG 119 Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS 172 + L + SK + E E+ +VIGK ++ A ++ G T + DW + K + Sbjct: 120 QPLLLPPE-SKQLDYEGEIGIVIGKAGRRIAKEDAHTHIAGLTCINEGTIRDWLHHGKFN 178 Query: 173 QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 232 + GK D IGPWIVT+DE + N+ + +NG +Q+ T + +I+ L Sbjct: 179 -VTQGKNFDASGAIGPWIVTADEFPDFDNIGLTTRVNGEVRQQDTTANLMFPFASLISYL 237 Query: 233 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFE--TRVEE 284 S TL PGDII TGTP G GV +PP FL PGDV+ E++ +G R EE Sbjct: 238 SQFATLNPGDIIATGTPIGAGVRFDPPRFLVPGDVVEVEVDGVGVLANVVRAEE 291 >UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Hyphomonas neptunium ATCC 15444|Rep: Fumarylacetoacetate hydrolase family protein - Hyphomonas neptunium (strain ATCC 15444) Length = 281 Score = 144 bits (350), Expect = 2e-33 Identities = 81/222 (36%), Positives = 118/222 (53%), Gaps = 5/222 (2%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L + L P K++C+GLNYK+H +E P P +F K ++V P+ L+ Sbjct: 61 LDQVGLLMPSEPLSKLVCLGLNYKNHVDETHNDLPPNPALFTKVADSLV-PHGEAVLRPK 119 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 VS+ E E+ VVIGK + A D+V GYTI D D++K+ + GK Sbjct: 120 VSEQFDYEGEICVVIGKGGRHISRETALDHVFGYTIMLDGSVRDYQKHS----VSAGKNF 175 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 +GPWIVT+DEI +P + ++ +NG Q + + ++ IP IA +S L P Sbjct: 176 WRSGALGPWIVTADEIPDPSVMKLETRLNGETVQSTTADLMLYDIPTAIAYVSQWTPLAP 235 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GD+I TGTPGGVG R PP +++ GDVI ++ IG V Sbjct: 236 GDVIATGTPGGVGARRKPPLWMKAGDVIEVDVSQIGVLSNPV 277 >UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Herpetosiphon aurantiacus ATCC 23779 Length = 293 Score = 144 bits (349), Expect = 2e-33 Identities = 76/175 (43%), Positives = 100/175 (57%), Gaps = 8/175 (4%) Query: 76 VLCVGLNYKDHCEEQ------KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 129 V CVGLNY H E ++ PE P F K P+ + P I + VS+ + E+ Sbjct: 76 VFCVGLNYAAHARESLQAKGLEVKMPEHPVFFTKPPTAINSPTGEIVIDPAVSERIDWEV 135 Query: 130 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 189 EL VVIGK + A ++V GYT+ D+ A D + + Q GKA+D CP+GPW Sbjct: 136 ELGVVIGKAGKNISHEQAMEHVWGYTVINDVSARDLQMRHQ--QFFKGKALDGSCPMGPW 193 Query: 190 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244 I+TSDE+ +P NL V+ +NG KQ+SNTN I IP +I LS MTL PGDII Sbjct: 194 IITSDELTDPHNLVVRLRVNGEIKQESNTNDLIFNIPTLIHVLSQGMTLEPGDII 248 >UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9; Ascomycota|Rep: Degradation of aromatic compounds - Pichia stipitis (Yeast) Length = 293 Score = 144 bits (349), Expect = 2e-33 Identities = 78/225 (34%), Positives = 119/225 (52%), Gaps = 7/225 (3%) Query: 65 TLKAPVHGND--KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122 TL P+ +D V CVGLN+ H +E TPP P IF K +V + I + Sbjct: 66 TLLGPLTPDDVPMVKCVGLNFMKHIQEGGRTPPPFPSIFYKTSFSVADFGEDIPIPKIAQ 125 Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK----ISQLLLGK 178 E EL +VIGK + A YV GY D+ + +W+K+ + + Q K Sbjct: 126 SKCDYEGELCIVIGKTGKNIKEEEALSYVAGYVTGNDVSSRNWQKDPEFAGSVPQWCFSK 185 Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTL 238 + D + P+GP +V+ I NP NL+++ ++NG +Q +NT+ + +P II+ +S TL Sbjct: 186 SFDKYAPLGPALVSPQVIQNPGNLSLQTTVNGEIRQDANTDDLLFGVPRIISFISQSTTL 245 Query: 239 LPGDIILTGTPGGVGVYRNP-PEFLQPGDVITSEIENIGTFETRV 282 G +I+TGTP GV + P P +LQ GDV+ I+ IGT ++ Sbjct: 246 EMGTVIMTGTPSGVALGMKPTPVYLQNGDVVEVAIDQIGTLSNKM 290 >UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase; n=4; Deinococci|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase - Deinococcus radiodurans Length = 262 Score = 144 bits (348), Expect = 3e-33 Identities = 81/208 (38%), Positives = 119/208 (57%), Gaps = 9/208 (4%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 KV+ + LNY DH E PE P +F K P+T + P+ + +K + E+EL +V Sbjct: 46 KVIALALNYADHVAELGFKAPEEPVMFLK-PNTSLLPHQGTVIYPRGAKFMHYEVELGIV 104 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IG+ A +V + A DYV GYTIA D+ D+ N + K DTF P+GP++V++D Sbjct: 105 IGRDARRVKAKDADDYVGGYTIANDLVVRDYVSNY-YRPPMRAKGWDTFGPLGPYLVSAD 163 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 E+ +P NL ++ +NG +Q+ +T I K P++I +S MTL GD+ILTGTP GV Sbjct: 164 EVPDPYNLGLRAYVNGELRQEGSTRDMILKAPELIEFMSRFMTLEAGDVILTGTPKGV-- 221 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282 + PGDV+ EI+ +G E V Sbjct: 222 -----SHVHPGDVMRLEIDGLGALENPV 244 >UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative FAA hydrolase family protein - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 282 Score = 144 bits (348), Expect = 3e-33 Identities = 82/189 (43%), Positives = 107/189 (56%), Gaps = 14/189 (7%) Query: 76 VLCVGLNYKDHCEEQKLTP-----------PELPFIFNKFPSTVVGPNDTIKLKMDVSKA 124 V CVG NY H E + PE P IF K S++ P I L + +A Sbjct: 87 VFCVGKNYHAHAHEFTKSGFDAGATAAEAIPEHPIIFTKPSSSLARPFGDIPLWPGLDEA 146 Query: 125 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 184 V E EL VVIGK + + A D+V GYT+ D+ A D +K K Q LGK +D F Sbjct: 147 VDYEAELAVVIGKAGRFITAERALDHVFGYTVFNDVTARDLQKKHK--QWFLGKGIDGFG 204 Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244 PIGPWIVT DE+ + N+ + C++NG ++QK++T I IP +I +S +TLLPGDII Sbjct: 205 PIGPWIVTKDEL-DIANVEITCTVNGEERQKTSTKDLIFDIPTLIEVISRSVTLLPGDII 263 Query: 245 LTGTPGGVG 253 TGTP GVG Sbjct: 264 ATGTPAGVG 272 >UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=9; Proteobacteria|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Burkholderia cenocepacia PC184 Length = 306 Score = 143 bits (347), Expect = 4e-33 Identities = 78/223 (34%), Positives = 119/223 (53%), Gaps = 4/223 (1%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L + + P +K+LCVGLNY DH E P +F +F S+++G + I L Sbjct: 77 LDAVRVLPPFGRPNKILCVGLNYLDHSMETGFAKQTYPTVFARFASSLIGHDQPIALPAQ 136 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 S+ + E EL VIGK + A D+V GY++ D+ D++ + Q +GK Sbjct: 137 SSQ-LDYEGELVAVIGKAGRGITRERALDHVAGYSLFNDVTLRDYQF--RTPQWTMGKNF 193 Query: 181 DTFCPIGPWIVTSDEIGNP-QNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 D GPW VT+DE+ + L ++ +NG Q+++T+ I I ++ LS VMTL Sbjct: 194 DGTGGFGPWFVTADELPRGCKGLRIQTRLNGAVVQEASTSDMIFDIETLVVMLSEVMTLQ 253 Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GD+I+TGTP G+G+ R P +++ GDV EIE +G V Sbjct: 254 AGDLIVTGTPAGIGMAREPQLWMKAGDVCEVEIEQLGVLRNAV 296 >UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Proteobacteria|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Marinomonas sp. MED121 Length = 298 Score = 143 bits (346), Expect = 5e-33 Identities = 84/260 (32%), Positives = 133/260 (51%), Gaps = 5/260 (1%) Query: 19 LDGDNVVDINKEDPKLPSTLIELLKT-NXXXXXXXXXXXXXXXLSGITLKAPVHGNDKVL 77 + G+ ++I+ +D + S L +++ +S I P+ KV+ Sbjct: 25 IQGELAINISSQDNQFGSDLSQIINNPQLLEKISGYSSAPGIPVSQIQPSLPLQHPGKVI 84 Query: 78 CVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGK 137 C+GLNY DH +E P+ P +F + S+++ P ++ VS + E EL +++GK Sbjct: 85 CLGLNYMDHIKEGGYKVPDYPALFMRSHSSLM-PAQAPMVRPKVSVQLDYEAELMLIVGK 143 Query: 138 KASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIG 197 + S A DYV GYTI D D+++ K Q GK D IGP IVT DE+ Sbjct: 144 HGRHIPESKALDYVFGYTIFNDGSVRDYQR--KTHQWTPGKNFDNTGAIGPIIVTPDELP 201 Query: 198 N-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYR 256 L ++ + Q +NT++ + + +IA +S+ TL PGD+I GTP GVG R Sbjct: 202 EGAHGLKIETRVGDEILQSANTSEMLWSVARVIAEISSYTTLEPGDLIAMGTPPGVGHAR 261 Query: 257 NPPEFLQPGDVITSEIENIG 276 +P +L+PG+V+ EIE IG Sbjct: 262 SPARWLEPGEVVEVEIEGIG 281 >UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA) hydrolase; n=1; Burkholderia xenovorans LB400|Rep: Putative fumarylacetoacetate (FAA) hydrolase - Burkholderia xenovorans (strain LB400) Length = 257 Score = 142 bits (345), Expect = 7e-33 Identities = 79/204 (38%), Positives = 113/204 (55%), Gaps = 12/204 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 ++ VG+NY H E P +P F + +GP + I ++ ++ V E EL +V Sbjct: 55 RLFAVGMNYVGHIAEAGAKTPVIPQFFMMPTTAAIGPGEAI-VRPREAQVVHHEAELAIV 113 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK-ISQLLLGKAMDTFCPIGPWIVTS 193 IG++ ++D A D+V GYT A D+ + + LL+GKA DTFCP+GP I T Sbjct: 114 IGRRGRRIDVERALDHVFGYTCANDVSERVIQNREMGYGCLLVGKAFDTFCPLGPVIATG 173 Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 + GN L V+ S+NG +Q NT+ + +P I++ LS +TLLPGD+ILTGTP GVG Sbjct: 174 LDAGN---LRVRASVNGSPRQDGNTSDLLFTVPHIVSYLSQAVTLLPGDVILTGTPSGVG 230 Query: 254 VYRNPPEFLQPGDVITSEIENIGT 277 L GDV I+ IGT Sbjct: 231 P-------LLSGDVCEITIDGIGT 247 >UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1; Filobasidiella neoformans|Rep: Mitochondrion protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 336 Score = 142 bits (345), Expect = 7e-33 Identities = 94/287 (32%), Positives = 153/287 (53%), Gaps = 12/287 (4%) Query: 1 MKLLQF-SYKNSDGIRAGFLDGDN--VVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXX 57 MK + + S + GI G +D V ++ D L T+ +L++ Sbjct: 18 MKFVSYRSRLHPQGI-VGLVDSTEQFVAPLSFPDNTLVRTMQQLIEEWDATHRHLLHGAP 76 Query: 58 XXXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPF--IFNKFPSTVVGPNDTI 115 L + + AP+ G D V+CVG NY++H E + + + IF K ++++G N I Sbjct: 77 MESLDIVEILAPLRGRD-VICVGKNYREHAEWVRSLFKLVKYVVIFTKRATSIIGTNQEI 135 Query: 116 KLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL 175 V++ + E EL ++IGK ++ A+DYV G TI D+ A + +++ K Q Sbjct: 136 YPHPRVTQTLDYEGELGIIIGKAGIQISREDAWDYVWGATIINDVTARERQRDHK--QFY 193 Query: 176 LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNV 235 +GK++DTFCP+GP+ V S + + +N+ ++ +NG +Q +NT+Q I IP +IA S Sbjct: 194 IGKSLDTFCPMGPYAVHSSVL-DWRNMMLETRVNGQIRQSANTSQLIFDIPALIATCSMG 252 Query: 236 MTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 +TL PGD+I TGTP GV + + EFL+ DVI + +GT V Sbjct: 253 ITLQPGDVISTGTPAGVCL--SSGEFLKHRDVIDISMSGLGTLSNTV 297 >UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Syntrophobacter fumaroxidans MPOB|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 235 Score = 141 bits (342), Expect = 2e-32 Identities = 83/224 (37%), Positives = 117/224 (52%), Gaps = 22/224 (9%) Query: 75 KVLCVGLNYKDHCEEQKLTP--------PELPFIFNKFPSTVVGPNDTIKLKMDVSK--- 123 K++ +GLNY+ H E PE P +F K P+ ++GP ++I + + + Sbjct: 19 KIIALGLNYRAHIAESTTVKVRGFTDEVPEEPILFPKTPNVLIGPGESIVIPAFLKEYGF 78 Query: 124 ---AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 E EL V+I + V A +V GYT D+ + + + GK++ Sbjct: 79 PEPRTDYEAELAVIIKDECKNVGPGDALKHVFGYTCMNDVSQRNLQTGDRAGWFR-GKSL 137 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 DTF PIGP IV D++G+P NL + C +NGV Q SNT I KIP+IIA +S L+P Sbjct: 138 DTFGPIGPVIVRPDDLGDPHNLRICCRLNGVTVQDSNTGSMIFKIPEIIAFVSRNFKLMP 197 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 GD+I+TGTP GVG R+ GDV+ EIE IG V E Sbjct: 198 GDVIVTGTPSGVGPIRH-------GDVVEVEIEKIGILRNPVVE 234 >UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=5; Actinomycetales|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Arthrobacter sp. (strain FB24) Length = 290 Score = 141 bits (342), Expect = 2e-32 Identities = 79/214 (36%), Positives = 119/214 (55%), Gaps = 4/214 (1%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 + L AP+ V+ +GLNY H E PE+P +F K +TV GP D + +S+ Sbjct: 68 LRLGAPLSRPGAVVGIGLNYAGHAAESGAAVPEVPVVFLKPSNTVAGPFDDAPIP-PLSR 126 Query: 124 AVVCEIELTVVIGKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDT 182 E+EL VVIG++AS + S A V GY +A D+ D++ Q + GK++ Sbjct: 127 KYDWEVELAVVIGQRASYLKSVDEAAGCVAGYVLANDLSERDYQLPGAAGQWVKGKSLPA 186 Query: 183 FCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGD 242 P+GPW V + ++ +P L ++ +NG +Q S+T I +P ++ LS M L PGD Sbjct: 187 STPLGPWFVPAADL-DPSALRLRTWVNGELRQDSSTADLIFDVPAVVHHLSQFMVLEPGD 245 Query: 243 IILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 +ILTGTP GV + P +LQ GDV+ E+E +G Sbjct: 246 VILTGTPEGVALSGRFP-YLQDGDVLELEVEGLG 278 >UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isomerase; n=4; Halobacteriaceae|Rep: 2-hydroxyhepta-24-diene-1,7-dioate isomerase - Haloarcula marismortui (Halobacterium marismortui) Length = 257 Score = 141 bits (342), Expect = 2e-32 Identities = 77/209 (36%), Positives = 115/209 (55%), Gaps = 12/209 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 KV+C+G NY DH EE P+ P +F K P+ V + + + + E EL VV Sbjct: 59 KVVCIGRNYADHAEEMDSELPDRPMLFLKAPNAVASHGKHLTMPSGKER-IDYEAELGVV 117 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IG++ V S A D V GYT DI D ++ ++ + GKA D CPIGP + T + Sbjct: 118 IGEQCRNVSESGAMDVVAGYTCVNDISNRDDQRREQ--NWVRGKAFDNACPIGPLVATPE 175 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 + P++ +++ +NG KQ S+ I +P++IA +++ MTL PGD+I TGTP GVG Sbjct: 176 HV--PEDASIELRLNGETKQSSSREHLIFSVPELIAEITSYMTLEPGDVIATGTPEGVGP 233 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRVE 283 ++ GD + EIE IGT + V+ Sbjct: 234 -------MEDGDEVEVEIEGIGTLKHSVK 255 >UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1; Streptomyces ambofaciens ATCC 23877|Rep: Putative maleylpyruvate isomerase - Streptomyces ambofaciens ATCC 23877 Length = 288 Score = 141 bits (341), Expect = 2e-32 Identities = 93/277 (33%), Positives = 139/277 (50%), Gaps = 22/277 (7%) Query: 15 RAGFLDGDNVVDINKE----DPKLPSTLIE-LLKTNXXXXXXXXXXXXX--XXLSGITLK 67 R G +DGD++VD+ + P+ ++ ++T L+ L+ Sbjct: 10 RLGVVDGDDLVDVTDQLTGAGTAGPAGAVQRYIETTARGEAVRFDLAGRPRTPLAEAALQ 69 Query: 68 APVHGNDKVLCVGLNYKDHCEEQKLTPPELPF-IFNKFPSTVVGPNDTIKLKMDVSKAVV 126 AP+ K++ +NY DH E + T +F K S+V+GP + I L K Sbjct: 70 APLPLPGKIIGAPVNYLDHKAEMEYTTSVADLGVFLKANSSVIGPGEDILLPYS-DKRTD 128 Query: 127 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPI 186 E EL VVIG+ A+ V + A +V GYT DI E K+ DTF P+ Sbjct: 129 QEGELGVVIGRTAAHVSADDALGHVFGYTCVLDITVRSGEDRST------RKSFDTFTPL 182 Query: 187 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 246 GPW+VT+DEI +P L+++C + G +Q++NT I + ++IA S+VMTL PGD+I T Sbjct: 183 GPWVVTADEIPDPDTLDLRCDVGGTTRQRTNTADLIFGVRELIAYTSSVMTLHPGDVIAT 242 Query: 247 GTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 GTP GVG L GD + +IE +G E V+ Sbjct: 243 GTPAGVGP-------LAHGDRVVLDIEKVGRLEVGVD 272 >UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=3; Dehalococcoides|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Dehalococcoides sp. BAV1 Length = 253 Score = 140 bits (339), Expect = 4e-32 Identities = 79/179 (44%), Positives = 105/179 (58%), Gaps = 6/179 (3%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++ +GLNYK H E P+LP IF K S ++GP D I +K S+ V E EL V+ Sbjct: 56 KIIAIGLNYKAHAGEMAEDLPKLPLIFFKNASGIIGPEDNI-IKPGQSERVDYEGELAVI 114 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 I KK + AFDY+LGY+ D+ A D +K Q K DTF GPWI T Sbjct: 115 IRKKTRNIKPEDAFDYILGYSCFNDVTARDLQKID--GQWSRAKGFDTFAVCGPWIET-- 170 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 E+ +PQ ++ +NG KQ+++T I IP I++ +S VMTLLPGDII TGTP G+G Sbjct: 171 EL-DPQVQLLETYLNGKLKQRTSTADMIFSIPRIVSFISEVMTLLPGDIIATGTPSGIG 228 >UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 250 Score = 140 bits (338), Expect = 5e-32 Identities = 80/208 (38%), Positives = 115/208 (55%), Gaps = 13/208 (6%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++CVG NY DH E P+ P +F K P+TV P + D + + E EL V Sbjct: 55 KIICVGKNYYDHAMEMGEGVPDRPILFIKAPNTVNHPEGEVSAP-DFVERLDYEGELAFV 113 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 + K+A V + DY+LGYT D+ A D +K+ Q GK+MD F PIGP + +D Sbjct: 114 VKKRAKNVKAEEYGDYILGYTCLNDVTARDIQKSD--GQWSRGKSMDGFAPIGPLV--TD 169 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 E+ +L ++ +NG Q S T+ F+ KIP ++ ++ MTL PGD++ TGTP G+G Sbjct: 170 EVDG-SDLKIETRLNGKTVQSSRTSLFMTKIPALMEFITASMTLEPGDVVTTGTPAGIGA 228 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282 +QPGDV+ EIE IGT + Sbjct: 229 -------MQPGDVVEVEIEGIGTLRNYI 249 >UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2- hydroxymuconate Delta-isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5- tricarboxylate decarboxylase) (OPET decarboxylase)]; n=42; Proteobacteria|Rep: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2- hydroxymuconate Delta-isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5- tricarboxylate decarboxylase) (OPET decarboxylase)] - Escherichia coli Length = 429 Score = 139 bits (337), Expect = 6e-32 Identities = 78/212 (36%), Positives = 114/212 (53%), Gaps = 9/212 (4%) Query: 71 HGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 130 H + + +GLNY DH E + PPE P +F K P+T+ G N T ++ + + + E E Sbjct: 220 HPHGTLFALGLNYADHASELEFKPPEEPLVFLKAPNTLTGDNQT-SVRPNNIEYMHYEAE 278 Query: 131 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWI 190 L VVIGK+A V + A DYV GYT+ D D+ +N L + K+ D P+ I Sbjct: 279 LVVVIGKQARNVSEADAMDYVAGYTVCNDYAIRDYLENYYRPNLRV-KSRDGLTPMLSTI 337 Query: 191 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 250 V + I +P NL ++ +NG +Q+ T I +P +IA LS MTL PGD+I TGTP Sbjct: 338 VPKEAIPDPHNLTLRTFVNGELRQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIATGTPK 397 Query: 251 GVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 G+ + PGD + E+E +G R+ Sbjct: 398 GL-------SDVVPGDEVVVEVEGVGRLVNRI 422 Score = 74.5 bits (175), Expect = 3e-12 Identities = 48/156 (30%), Positives = 70/156 (44%), Gaps = 9/156 (5%) Query: 94 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 153 PP+ F K +TV+G + I + V+ + +++GK A+KV A +Y+ G Sbjct: 31 PPKTAVWFIKPRNTVIGCGEPIPFPQ--GEKVLSGATVALIVGKTATKVREEDAAEYIAG 88 Query: 154 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213 Y +A D+ + + K D FCPIG + S N NL + ING Sbjct: 89 YALANDVSLPE---ESFYRPAIKAKCRDGFCPIGETVALS----NVDNLTIYTEINGRPA 141 Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 249 NT +++ LS TL PGD IL GTP Sbjct: 142 DHWNTADLQRNAAQLLSALSEFATLNPGDAILLGTP 177 >UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=3; Desulfovibrio|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Desulfovibrio desulfuricans (strain G20) Length = 264 Score = 139 bits (336), Expect = 9e-32 Identities = 80/208 (38%), Positives = 113/208 (54%), Gaps = 12/208 (5%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128 PV K++CVG+N++DH EE PE P F K S V+G + L + S V E Sbjct: 44 PVVTPSKIVCVGMNFRDHAEEIGFPVPEEPVFFLKPSSAVIGSGQPVVLPAE-SGRVEHE 102 Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188 EL VVIG+ A + +V GYT A D+ A D + + K DTF P+GP Sbjct: 103 AELGVVIGRAARNITPEDVPAHVFGYTCANDVTARDLQSRDGLFGRC--KGFDTFAPVGP 160 Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248 WI T E+ + +L ++ +NG +Q+ +T + +I+A +S VMTLLPGD+ILTGT Sbjct: 161 WIET--EVPDLSSLGIRAMVNGELRQQGSTADMLFSPHEIVAAVSRVMTLLPGDLILTGT 218 Query: 249 PGGVGVYRNPPEFLQPGDVITSEIENIG 276 P GVG L+ GD + EI+ +G Sbjct: 219 PAGVGP-------LEDGDEVRVEIDGVG 239 >UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family protein; n=13; Campylobacter|Rep: Fumarylacetoacetate hydrolase family protein - Campylobacter jejuni subsp. jejuni CF93-6 Length = 292 Score = 139 bits (336), Expect = 9e-32 Identities = 77/214 (35%), Positives = 115/214 (53%), Gaps = 8/214 (3%) Query: 76 VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 129 ++C+G+N+ DH +E +K E P F K + P +I L DV+ + E Sbjct: 77 IICLGINFLDHAKESAQFKGEKFEEREYPVYFGKRCNQATAPFGSISLHADVTSQLDYEC 136 Query: 130 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 189 EL ++ K A K+ + A DY+ GYTI +I A D +K K Q K+++ +GP+ Sbjct: 137 ELAFILSKDAYKIKAEDAKDYIFGYTIINEISARDLQKRHK--QFYRAKSLEGSTIMGPY 194 Query: 190 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 249 I + DEI P L++K +N +Q SNT FI I ++ LS+ M L G II GTP Sbjct: 195 ITSVDEIAYPPELHLKSYVNKELRQNSNTKFFIFDIGYVLEELSSGMLLKAGTIISMGTP 254 Query: 250 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 GVG+ NPP FL+ GD + IEN+G +++ Sbjct: 255 SGVGMGLNPPVFLKKGDEVRCVIENLGELCNKIK 288 >UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE / 5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE DECARBOXYLASE; n=19; Proteobacteria|Rep: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE / 5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE DECARBOXYLASE - Brucella melitensis Length = 311 Score = 138 bits (334), Expect = 1e-31 Identities = 81/282 (28%), Positives = 133/282 (47%), Gaps = 6/282 (2%) Query: 7 SYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX--LSGI 64 S+ G G L D +VD++ TL E+++ LS I Sbjct: 29 SFSTCGGRHYGVLKEDGIVDLSARHGSRWPTLREVIEAGVLAQLAQEAAGLAADVPLSSI 88 Query: 65 TLKAPVHGNDKVLCVGLNYKDHCEEQK--LTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122 T + P+ K++CVG+N+ D EE K P P +F +FP + G + ++ S Sbjct: 89 TYEIPIPSPGKIICVGVNFPDRNEEYKDGQAAPANPSLFVRFPRSFTGHERPL-MRPPES 147 Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDT 182 + E E+ +VIGK ++ A D++ T+ + DW ++ K + + GK D Sbjct: 148 PQLDYEGEIAIVIGKGGRRIAEKDALDHIAALTLCNEGTIRDWVRHAKFN-VTQGKNFDA 206 Query: 183 FCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGD 242 IGPW+V + ++ + +NG +Q+ T++ I II +S TL+PGD Sbjct: 207 TGSIGPWLVPYTDESQIADIQLTTRVNGEVRQQDRTSRMIFSFRKIINYVSTFTTLVPGD 266 Query: 243 IILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 +I+ GTP G G +PP +L+PGDV+ E E IG + + Sbjct: 267 VIVCGTPTGAGARFDPPIWLKPGDVVEVEAEGIGLLRNTIAD 308 >UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Acidobacteria bacterium Ellin345|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Acidobacteria bacterium (strain Ellin345) Length = 263 Score = 137 bits (332), Expect = 3e-31 Identities = 78/211 (36%), Positives = 111/211 (52%), Gaps = 12/211 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++CVG NYK H EE P+ P IF+K S ++ P IK +S+ V E EL V+ Sbjct: 63 KIVCVGRNYKAHAEELGHEIPKYPLIFSKPTSAIIAPGADIKRPAKLSQRVDYEGELGVI 122 Query: 135 IGKKASKVDSSH-AFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193 IG++ + H Y+ GYT+ D+ A D + K Q K DTFCP+GP + + Sbjct: 123 IGRECRHIPEDHDVRSYIHGYTVVNDVTARDLQ--NKDGQWTRAKGFDTFCPVGP--IVN 178 Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 D + + V+ +NG +Q NT+ FI + I+ +S VMTL PGD+I TGTP GVG Sbjct: 179 DALDPWTGVEVETRVNGAVRQHGNTSSFIFPLDVILRFISEVMTLFPGDLIATGTPEGVG 238 Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 + GDV+ + IGT V + Sbjct: 239 P-------IIAGDVVEVSVAGIGTLRNPVAD 262 >UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase; n=2; Actinomycetales|Rep: Possible fumarylacetoacetate hydrolase - Rhodococcus sp. (strain RHA1) Length = 281 Score = 137 bits (332), Expect = 3e-31 Identities = 84/222 (37%), Positives = 119/222 (53%), Gaps = 9/222 (4%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKF-PSTVVGPNDTIKLKMDVS 122 +++ PV + +V+CVGLNYK H E TPP P +F ++ PS V D + + Sbjct: 57 VSVVPPVPDSARVICVGLNYKAHAAEGGFTPPPYPTLFGRWTPSLSV---DGAPTPVPAN 113 Query: 123 KAVV-CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMD 181 +A + E E+ IG + VD++ VLGY D+ A + K +Q LGK D Sbjct: 114 EAGLDWEGEVAAFIGTRLESVDAATGQAGVLGYACFNDLTAR--KAQKLTAQWTLGKNGD 171 Query: 182 TFCPIGPWIVTSDEIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 P+GP +V + E+G+ L V+ +NG Q NT I + +IIA +S TL P Sbjct: 172 RSGPLGP-LVPAGEVGDLSDGLRVQTRVNGTVVQDGNTRDLIFSVGEIIALVSETFTLHP 230 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GDII TGTP GVG RNPP L PGD++ EI+ +G T + Sbjct: 231 GDIIATGTPEGVGYVRNPPWLLGPGDIVEVEIDKLGVLRTPI 272 >UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=4; Burkholderiales|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 284 Score = 137 bits (331), Expect = 3e-31 Identities = 75/224 (33%), Positives = 120/224 (53%), Gaps = 4/224 (1%) Query: 62 SGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV 121 + +T PV K+LCVGLNY DH +E P+ P +F + P+++VG +D ++ Sbjct: 60 AALTWLPPVISPRKILCVGLNYADHTKESPYEQPDYPTLFLRVPTSMVG-HDCAIVRPLA 118 Query: 122 SKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMD 181 S + E EL VVIGK + A +V GY++ D +++ K Q +GK D Sbjct: 119 SDTLDYEGELAVVIGKGGKHIAREDALSHVFGYSVFNDGSVREYQF--KSPQWTVGKNFD 176 Query: 182 TFCPIGPWIVTSDEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 GP++VT+DE+ L ++ +NG Q ++T+ ++ + +IA +S +TL P Sbjct: 177 ATGGFGPYVVTADELPPGATGLRLETRLNGQVVQSASTSDMLYDVASLIAIISEAITLEP 236 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 GD+I+ GTP G+G R P ++ GDV IE IGT + + Sbjct: 237 GDVIVAGTPSGIGWAREPKLLMRHGDVCEVSIERIGTLSNPIAD 280 >UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family protein; n=2; Cystobacterineae|Rep: Fumarylacetoacetate hydrolase family protein - Stigmatella aurantiaca DW4/3-1 Length = 257 Score = 137 bits (331), Expect = 3e-31 Identities = 83/224 (37%), Positives = 121/224 (54%), Gaps = 16/224 (7%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVV-GPNDTIKLKM 119 LS +TL P + KV+C+G NY+ H EE P P +F K PST + GP I+L Sbjct: 46 LSSLTLLVPSEAS-KVVCIGQNYRKHAEEMGKPVPSEPLLFIK-PSTALNGPRSPIRLPK 103 Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179 S+ V E EL +VIG++ D + A + G T D+ A D ++ + Q K+ Sbjct: 104 -ASQEVHYEAELGLVIGERLKNADEATAARAIWGLTCINDVTARDIQRREV--QHTRAKS 160 Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 DTF +GPW VT +P +L + C +NG +Q S T+ + +++ +S++MTLL Sbjct: 161 YDTFACVGPWAVTGL---SPADLRILCRVNGQVRQDSRTSDMVFNPAQLVSFISHIMTLL 217 Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 PGD++ TGTP GVG L GD++ E+E IGT VE Sbjct: 218 PGDLVSTGTPSGVGA-------LAAGDMVEVELEGIGTLANPVE 254 >UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Methylobacterium sp. 4-46|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Methylobacterium sp. 4-46 Length = 288 Score = 137 bits (331), Expect = 3e-31 Identities = 73/211 (34%), Positives = 115/211 (54%), Gaps = 4/211 (1%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++C+G NY H E P + P +F + +++V + + ++ S E EL V Sbjct: 79 KIICIGRNYAAHAREGGAEPLDYPDVFMRGANSLVAHGEPL-IRPRCSDKFDYEGELVFV 137 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 +G+KA V A + GY++ + D+++ + +Q +GK D GP +VT D Sbjct: 138 VGRKARHVGLDEACGIIAGYSVFNEGSIRDYQR--RATQWTMGKNFDGTGGFGPDLVTPD 195 Query: 195 EIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 E+ + L + ++NG Q NT+ FI + I+A L+ MTL PGD++LTGTP GVG Sbjct: 196 ELPDGADGLRLTTTLNGHVMQDGNTHDFIFPVARIVAILTEAMTLEPGDVVLTGTPSGVG 255 Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 RNPP F++PGDV+ IE +GT V + Sbjct: 256 YARNPPVFIKPGDVVEVTIEKVGTLRNTVRD 286 >UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Actinomycetales|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 279 Score = 136 bits (329), Expect = 6e-31 Identities = 73/220 (33%), Positives = 117/220 (53%), Gaps = 8/220 (3%) Query: 66 LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125 L A V K++CVGLNY +H +E P+ P +F KFP ++GP D + + +KA+ Sbjct: 60 LDAVVPAPKKIVCVGLNYANHIKEMGRDLPDTPTLFVKFPDALIGPFDDVVVPEWANKAL 119 Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTF 183 E E+ V+IGK+A +V + A +Y+ GY + D D++ K Q GK+++ Sbjct: 120 DWEGEMAVIIGKRARRVKQADAAEYIAGYAVMNDYTTRDFQYAAPAKTPQWHQGKSLEKS 179 Query: 184 CPIGPWIVTSD--EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241 GPW+ T D E G + + G + Q + TN + +I ++++ L G Sbjct: 180 AGFGPWMTTPDSFEFGG----ELATYLEGEKVQSTPTNDLVFSPEKLIEYITHIYPLDAG 235 Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETR 281 D+I+TGTPGGVG RNP ++ G+ + EI +G E + Sbjct: 236 DVIVTGTPGGVGHARNPQRYIGDGETVKVEIAGLGFIENK 275 >UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Planctomyces maris DSM 8797|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Planctomyces maris DSM 8797 Length = 310 Score = 136 bits (329), Expect = 6e-31 Identities = 83/232 (35%), Positives = 120/232 (51%), Gaps = 15/232 (6%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPE----LPFIFNKFPSTVVG-PNDTIKLK 118 + L PV K+L + NY H EE E P++F K PST + P +K+ Sbjct: 80 VQLLVPVPEPSKLLLLAGNYSKHIEEGGGKAEERQKTFPYVFMKPPSTTLTHPGQPVKIP 139 Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNK--------K 170 + E+EL +VIGK V + A DYV GYT+ DI + N Sbjct: 140 EVSPDYIDWELELGIVIGKSCKGVSEAEALDYVAGYTVINDISDRKFRPNPGRTLREKDT 199 Query: 171 ISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIA 230 GK DTFCP+GP + +D+I +PQ L +K S+NG +Q ++T + I + I+ Sbjct: 200 FFDWQHGKWHDTFCPMGPCVTPADDIPDPQTLKMKLSVNGNVEQDASTAEMIFPVAAIVE 259 Query: 231 RLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 +S+ + L PGD+I TGTP GVG +N +FL+ GDV+ +EI+ IG V Sbjct: 260 FISSFVQLEPGDVISTGTPSGVGASKN--KFLKNGDVMKAEIDQIGVLTNPV 309 >UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_03001459; n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical protein Faci_03001459 - Ferroplasma acidarmanus fer1 Length = 274 Score = 135 bits (327), Expect = 1e-30 Identities = 80/211 (37%), Positives = 116/211 (54%), Gaps = 8/211 (3%) Query: 76 VLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 +LC+GLNYK H E PE P +F+K + G + ++ + E EL V+ Sbjct: 69 LLCIGLNYKSHVSEHAGGKIPETPVVFSKANNAFTGNHSIVQTGNGMHMDY--EGELCVM 126 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IGK A V ++A +YVLGY I D+ + + K +Q LGK+ D F P GP+I + Sbjct: 127 IGKTARNVGEANALNYVLGYFIGNDVSSRLMQY--KTTQFFLGKSFDNFYPNGPYI-SIG 183 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV-- 252 EI +PQNL ++ +NG +Q SNT I + +I+ +S MTL PGD I TGTP GV Sbjct: 184 EINDPQNLTIQTRVNGELRQDSNTGLMIFPVNKLISYISQFMTLRPGDCISTGTPAGVIM 243 Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 G+ + ++L GD + +I +G ET E Sbjct: 244 GMPESNQKWLGKGDKVEVQITGLGKLETTFE 274 >UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Mesorhizobium sp. (strain BNC1) Length = 293 Score = 135 bits (327), Expect = 1e-30 Identities = 88/280 (31%), Positives = 139/280 (49%), Gaps = 28/280 (10%) Query: 12 DGIRAGFLDGDNVVDINKE---DPKL--PSTLIELLKTNXXXXXXXXXXXXXXX---LSG 63 DG R G + GD +VD+ DP P +++++ L+ Sbjct: 7 DGGRIGVVSGDRIVDVTPAAGVDPASWPPVGMVQVIANFERLRATFQHQLDAGGGKPLAS 66 Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFI-------FNKFPSTVVGPNDTIK 116 + L+ P+ +KV+ NY H +E K + F K S++ GP D I Sbjct: 67 VRLECPIAWPNKVVAFPANYHAHIDEMKAGSGLISNFAAAGQGFFLKANSSLSGPADPIV 126 Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176 L + V E EL V+IGK+ + +A +V GY+ D E+ ++ Sbjct: 127 LPNLDGREVHHESELAVIIGKRGRNIPRENALQHVFGYSCLIDAVVRGKEER------VM 180 Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236 K+ DTFCP+GPW+VT++E+ +P N++++ ++NG +QK+NT I +P++IA S+VM Sbjct: 181 RKSYDTFCPLGPWLVTAEEVPDPANIDIELTVNGEVRQKANTRALIVDVPEMIAMASSVM 240 Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 TL PGDII +GTP GVG + PGD + I +G Sbjct: 241 TLEPGDIIASGTPSGVGP-------MLPGDAVCITIAGVG 273 >UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Mesorhizobium sp. BNC1|Rep: Fumarylacetoacetate (FAA) hydrolase - Mesorhizobium sp. (strain BNC1) Length = 307 Score = 135 bits (326), Expect = 1e-30 Identities = 99/298 (33%), Positives = 134/298 (44%), Gaps = 33/298 (11%) Query: 7 SYKNSDGIRAGFLDGDNVVDINK-----EDPKLPSTLIELLKTNXXXXXXXXXXXXXXXL 61 SY GIR + D VD +P L + L Sbjct: 8 SYSGPRGIRTAAVKADRYVDAADVTGVAAHASMPGLLADWAAAERPLQAAFAAGQAMVGL 67 Query: 62 SGITLKAPVHGNDKVLCVGLNYKDHCEE----------------QKLTPPELPFIFNKFP 105 + P+ G + C+G NY DH E Q+ P+ F K Sbjct: 68 PKLVAPLPLPG--AIYCIGANYADHIAEMQGGGTNGASVAAERKQQKEDGLKPWFFIKSS 125 Query: 106 STVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW 165 +V GP + L SK V E EL VVIG+K+ + +A V GYTIA D+ A D Sbjct: 126 HSVCGPETKVALPA-TSKKVDWEAELAVVIGRKSRDLTIENALTAVWGYTIANDLSARDL 184 Query: 166 EKNKKISQ-------LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNT 218 + + Q K+ D CP+GPWIV++ +I + +L++ SING QKSNT Sbjct: 185 SRRPPLPQGSPFFFDWTSHKSFDDSCPMGPWIVSASQIVDANDLDIGLSINGQPMQKSNT 244 Query: 219 NQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 +Q I + + +A LS +TL PGDIILTGTP GVG RN L+P D ++ IE IG Sbjct: 245 SQMIFTVAEQVAHLSQRITLWPGDIILTGTPAGVGAGRNLS--LKPSDEVSVYIEGIG 300 >UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase related protein; n=3; Archaea|Rep: 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase related protein - Thermoplasma acidophilum Length = 250 Score = 134 bits (324), Expect = 2e-30 Identities = 70/219 (31%), Positives = 114/219 (52%), Gaps = 7/219 (3%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128 P K+ +N++ H +E P P+ F KF + +VG N T ++ K + E Sbjct: 32 PAVNPGKIFLPAVNFRSHSQESDTKFPPKPYFFTKFSNALVGHNGTAHRPREIEK-LDYE 90 Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW---EKNKKISQLLLGKAMDTFCP 185 E+ +VIGK+ ++ A +Y+ G+TI D+ A D+ E + + GKA D P Sbjct: 91 GEIGIVIGKRGKRIGVEEAQNYIFGFTIVDDVSARDYQFPEMHPYGYNWVQGKAFDEALP 150 Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 +GP+IVT DEI P L ++ +NG +Q T + + +I+ +S +TL PGD+I Sbjct: 151 VGPYIVTRDEIRFP--LKIETRVNGELRQSGTTEDMVFSVEQLISTVSQTITLEPGDLIT 208 Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 TGTP GV + ++L GD ++ + IG R+E+ Sbjct: 209 TGTPAGVAAF-TEAKYLSDGDTVSISVSGIGELVHRIED 246 >UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=2; Microbacteriaceae|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Leifsonia xyli subsp. xyli Length = 291 Score = 133 bits (322), Expect = 4e-30 Identities = 74/206 (35%), Positives = 111/206 (53%), Gaps = 2/206 (0%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 +V+ +G NY H E KL + +F+ +P+++ G T D++ V E EL V+ Sbjct: 83 QVIAIGANYAAHASELKLRSEKAATVFSLWPNSLAGHGGTTSWPGDLATQVDYEAELGVI 142 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IGK A V + A DYV GYT+ DI A D + ++ +Q K+ D F P GP VT+D Sbjct: 143 IGKPARDVLAQDALDYVWGYTVVNDITARDLQFSE--AQWSRCKSFDGFTPNGPVAVTAD 200 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 E+ +PQ+L + +++G Q ++T + + +II LS T+ G +I TG+PGG G Sbjct: 201 EVPDPQDLWLTTNVDGAILQDASTADMVRSVAEIIEFLSRSATIPAGTLISTGSPGGAGY 260 Query: 255 YRNPPEFLQPGDVITSEIENIGTFET 280 R PP FL +T I IG T Sbjct: 261 SRTPPVFLHDRSTVTVSIGGIGYLTT 286 >UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Comamonas testosteroni KF-1 Length = 286 Score = 133 bits (322), Expect = 4e-30 Identities = 74/228 (32%), Positives = 119/228 (52%), Gaps = 10/228 (4%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDT 114 L+ +T + +K++C NY DH +E Q+ E P + S Sbjct: 59 LADVTFLPVIPRPEKIVCAVRNYMDHHQEVLAAGMQRELSEEPPIFLRVWRSQTAHQGPI 118 Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174 ++ VS ++ E EL V+IG+ + + A++++ GY+ D +W+ + K Q+ Sbjct: 119 VR--PHVSDSLDWEGELAVIIGQGGRDIAEADAWEHIAGYSCYNDASVREWQFHAK--QI 174 Query: 175 LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSN 234 GK ++ GPW+VT+DEI + L ++ +NG Q S+T I IP +IA S Sbjct: 175 ASGKNFESTGAFGPWMVTADEISPGRELKLETRLNGAVVQSSHTGHMIFSIPRLIAYAST 234 Query: 235 VMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 + TL+PGD+I+TGTP GVG + P +F++ GDV+ EIE IG V Sbjct: 235 IFTLVPGDVIITGTPAGVGWSKKPQQFMKAGDVVEVEIEAIGLLRNPV 282 >UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=3; Bacillaceae|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Geobacillus kaustophilus Length = 262 Score = 132 bits (320), Expect = 7e-30 Identities = 82/214 (38%), Positives = 122/214 (57%), Gaps = 14/214 (6%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 ++L AP+ V+ +G NY E+ + P++P F K S+VVGP + + V + Sbjct: 45 VSLVAPLAPRH-VIGIGANYVASSEQLPVELPDIPVFFFKPSSSVVGPEAEVVIPSGVGE 103 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183 V E EL VVIGK+A +V + Y+ GYT+A D+ A + +GK+ DTF Sbjct: 104 -VKFESELAVVIGKEAKQVSEEDVWSYIFGYTVANDVTAPQFFHPD--GHWTIGKSFDTF 160 Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243 P+GP I T E+ +P+ ++VK +NG +KQ S+T I I +I+ LS+VMTL PGD+ Sbjct: 161 TPLGPVIET--EL-DPRAVSVKARVNGEEKQNSSTKLMIISISKMISYLSHVMTLQPGDV 217 Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGT 277 ILTG+P G E + PG VI +++ IGT Sbjct: 218 ILTGSPVGA-------ELVGPGTVIECDVDGIGT 244 >UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Fumarylacetoacetate hydrolase family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 285 Score = 132 bits (320), Expect = 7e-30 Identities = 74/223 (33%), Positives = 120/223 (53%), Gaps = 8/223 (3%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP---PELPFIFNKFPSTVVGPNDTIKLKMD 120 +TL PV KV+C+GLNY H E PE P +F ++PST+ I + D Sbjct: 57 VTLVPPVLPGAKVICIGLNYLKHVAEGSYGAEPLPEFPTLFARWPSTLTVDGAQIPVPTD 116 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 + + E E+ +G++ S + A D V+GY+ D+ A K SQ +LGK Sbjct: 117 -EEGLDWEGEVVAWVGRELSCATADEALDAVVGYSTFNDVTAR--RAQKITSQWILGKNA 173 Query: 181 DTFCPIGPWIVTSDEIGNPQN-LNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 D P+GP +V + ++G+ ++ L V+ +NG Q ++T++ ++ + + +A +S +TL Sbjct: 174 DRSGPLGP-LVPAHDVGDLRDGLRVRTRVNGTTVQDASTDEMVYTVGETLAHISRTLTLR 232 Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 PGD++ TGTP GVG R P L PGD + E+E +G + Sbjct: 233 PGDLLATGTPSGVGYARTPAWLLHPGDHVEVEVEKLGVLRNTI 275 >UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep: Fumarylacetoacetate hydrolase family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 291 Score = 132 bits (319), Expect = 1e-29 Identities = 81/228 (35%), Positives = 127/228 (55%), Gaps = 9/228 (3%) Query: 62 SGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPEL---PFI-FNKFPSTVVGPNDTIKL 117 +G L AP+ + G N+K+H +E K P+I F + +VGP D I+ Sbjct: 56 AGGRLLAPIKPTKLIHTAG-NFKEHEDESKRVGWSHNVGPWIVFMQNVDAIVGPEDGIRY 114 Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL-L 176 ++K + E+EL+VVI + + A +YV GY I D+ A D ++++ S + Sbjct: 115 PDHLTKELDYELELSVVINQDVGEFAPEDAMNYVAGYVIFNDVTARDIQRDEMKSGVFGF 174 Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236 K +D+FCPIGPWIVT+DEI NP +L ++ +NG +Q+S++++ IP+I+AR S + Sbjct: 175 CKGIDSFCPIGPWIVTADEIPNPHDLKMELRVNGEPRQESHSSRMWTTIPEILARYS-PL 233 Query: 237 TLLPGDIILTGTPGGVGVYRNPPE--FLQPGDVITSEIENIGTFETRV 282 GDI+ TGT GV +R E +L+ GD + E+E IG V Sbjct: 234 GYSAGDIVTTGTVSGVAGFRVDAEDYYLRVGDSVECEVEKIGVLRNTV 281 >UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Hyperthermus butylicus DSM 5456|Rep: Fumarylacetoacetate (FAA) hydrolase - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 338 Score = 132 bits (318), Expect = 1e-29 Identities = 73/222 (32%), Positives = 117/222 (52%), Gaps = 2/222 (0%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 LS + L APV +K++C+G+NY+ H E + P P +F K +++VGP D + + Sbjct: 107 LSAVRLLAPVDKPEKIICIGVNYRAHARESGVELPGTPNLFVKTGNSIVGPGDPVVVH-S 165 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 V + E+EL VIG A + S A D V G+ + D+ + ++ ISQ K+ Sbjct: 166 VGLKLDGEVELAAVIGIPARSIPPSEAPDVVWGFMVLNDVTSRLEQRELGISQWWRAKSH 225 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 DT+ P GP IV + + + ++ ++G+ ++ NT +H + DI++ S L+P Sbjct: 226 DTYAPTGPIIVPRHMV-SIGDTELELVVDGIVARRGNTGDMVHSVWDIVSVASTSALLVP 284 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GDII TGTP G P + +PG V+ + IG E RV Sbjct: 285 GDIICTGTPAGTMPDGKPAKTPEPGSVMRACARGIGCIENRV 326 >UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD - Pseudomonas abietaniphila Length = 293 Score = 131 bits (317), Expect = 2e-29 Identities = 81/217 (37%), Positives = 115/217 (52%), Gaps = 6/217 (2%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128 P+ +V VGLNY H + T PE P + K S +VG +D I+ ++ + E Sbjct: 63 PLEPGARVFGVGLNYLSHLQHLGSTAPEHPLGYIKPESALVGASDDIQYPA-LTAQLDYE 121 Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188 +EL VI + D A +LGYT DI A D K LL KAMD P+GP Sbjct: 122 VELVAVIARALG--DEPCASACLLGYTCGNDISARDAGKRIGRLDLLTQKAMDRTTPVGP 179 Query: 189 WIVTSDEIGNPQ-NLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247 W+VT DEIG Q +L+++ S+N +Q NT Q + I +++ + +TL PGD++ TG Sbjct: 180 WVVTLDEIGVGQPHLDIELSVNDECRQFDNTRQMLFPIDELLNYVDARITLQPGDLVFTG 239 Query: 248 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 + GVG+ FLQPGD + IE IG+ RV + Sbjct: 240 STHGVGL--EDGRFLQPGDRVEVRIEGIGSMSNRVSQ 274 >UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Nocardioides sp. JS614|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Nocardioides sp. (strain BAA-499 / JS614) Length = 269 Score = 131 bits (317), Expect = 2e-29 Identities = 84/224 (37%), Positives = 113/224 (50%), Gaps = 11/224 (4%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L + L APV KV+ +G NY H E P P +F K ++V+GP D I Sbjct: 54 LEDVRLLAPVLPRSKVVGIGRNYAAHAAELGNDLPTEPLMFLKPNTSVIGPGDPIFYPPQ 113 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 + E EL VVIG+ V A D + GYTI D+ A D +++ Q K Sbjct: 114 TQN-LHYEGELAVVIGRICRDVPPEQATDVIHGYTIGNDVTARDLQRSDV--QFTRAKGF 170 Query: 181 DTFCPIGPWIVTS-DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 D+FCP+GPWI T D + +V+ +NG Q +T I IP +IA +S+VMTLL Sbjct: 171 DSFCPLGPWIETDLDPHDFAEGRSVQTHLNGDLVQDGSTKDLIFDIPTLIAYVSSVMTLL 230 Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 PGD+ILTGTP GVG + GD + I +GT V+ Sbjct: 231 PGDVILTGTPEGVGP-------MDVGDEVEVSIAGLGTLTNPVK 267 >UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF; n=1; Pseudomonas alcaligenes|Rep: Putative uncharacterized protein xlnF - Pseudomonas alcaligenes Length = 287 Score = 131 bits (316), Expect = 2e-29 Identities = 82/233 (35%), Positives = 119/233 (51%), Gaps = 23/233 (9%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP-----PELPFI-----FNKFPSTVVG 110 L +TL +PV K++ +NY DH +E E+ I F K S+ VG Sbjct: 68 LDAVTLISPVGNPGKIIAAPVNYADHLDESNQDKGINFGTEISLIDKYALFLKAGSSSVG 127 Query: 111 PNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK 170 P++ I L + E+EL +VIGK+ +V A V GY I DI E Sbjct: 128 PDEGISLPAVEGRRFDHEVELALVIGKETRRVTVDEALSSVAGYFIGLDITMRGTEDRS- 186 Query: 171 ISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIA 230 K+ D+F +GPW+VTSD G+P+ + S+NG Q+Q +NTN + + II+ Sbjct: 187 -----YRKSFDSFTVMGPWLVTSDAFGSPEGVAFSLSVNGEQRQNANTNDLVWSVAKIIS 241 Query: 231 RLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 S+ TL PGD+ILTGTP GVG ++ GD I++ I+ IG+ E V+ Sbjct: 242 VASHAYTLYPGDVILTGTPAGVGP-------IKAGDKISASIDRIGSMEVPVK 287 >UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6; Pezizomycotina|Rep: Contig An05c0060, complete genome - Aspergillus niger Length = 290 Score = 131 bits (316), Expect = 2e-29 Identities = 79/214 (36%), Positives = 112/214 (52%), Gaps = 9/214 (4%) Query: 76 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND-TIKL-KMDVSKAVVCEIELTV 133 + C+GLNY DH +E L PE+P +F K S ++GP +I + K E EL V Sbjct: 76 IRCLGLNYIDHAKEANLALPEVPILFTKPRSALIGPYPASISVPKCAQDGTSDYESELCV 135 Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG-----P 188 VIG+ + +A DYVLGYT + D+ A + +Q K +D CPIG P Sbjct: 136 VIGRTGRDIPEENALDYVLGYTASNDVSARTLQM--ATAQWSFSKGLDESCPIGIDRTGP 193 Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248 +V+ I +PQ L ++ NGV Q +T I I I+ LS TL G I LTGT Sbjct: 194 VLVSPSVIKDPQTLRIQGIHNGVVVQDGHTKDMIFSIKRQISYLSQGTTLEAGTIFLTGT 253 Query: 249 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 P G+G +++P + L+ GD + I+ IGT +V Sbjct: 254 PAGIGYFKSPRDVLKDGDEFSVYIDKIGTLTNKV 287 >UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2; Proteobacteria|Rep: Putative hydratase - Polaromonas naphthalenivorans (strain CJ2) Length = 289 Score = 130 bits (315), Expect = 3e-29 Identities = 95/290 (32%), Positives = 137/290 (47%), Gaps = 33/290 (11%) Query: 12 DGIRAGFLDGDNVVDINKEDPKLPS---------TLIELLKTNXXXXXXXXXXXXXXXLS 62 D R G +DG+ V D+ LP+ LI LL L+ Sbjct: 7 DNDRLGLVDGETVRDVTAALDVLPNHRYPLPIFDPLIALLPEVLEAIRRIAPSSPTLPLA 66 Query: 63 GITLKAPVHGNDKVLCVGLNYKDHCEEQK----------LTPPELPFIFNKFPSTVVGPN 112 G L APV KV+ +NYK H +E + + E +F K S+VVGP+ Sbjct: 67 GRRLLAPVANPGKVIAAPVNYKKHLQEAREQVEIHHNNQVAEIEKIGLFLKATSSVVGPS 126 Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS 172 ++++ + E EL VIGK + AFD++ YTI D+ ++ Sbjct: 127 HGVEIQHP-DRRNDHEAELVAVIGKTGRNIPRERAFDHISAYTIGLDMTVRGPQERS--- 182 Query: 173 QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 232 L K++DT+ +GPW+VT+DEI +PQ L+ ++NG ++QK+NT + IP +I Sbjct: 183 ---LRKSIDTYSVVGPWLVTADEIDDPQALDFWLTVNGERRQKANTRDLVLDIPALIEMA 239 Query: 233 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 S+ TL PGD++ TGTP GVG N GD IT EI IG V Sbjct: 240 SSYYTLQPGDLLFTGTPEGVGPVVN-------GDEITVEIAGIGRMNVAV 282 >UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate isomerase; n=1; Thermoplasma volcanium|Rep: 2-hydroxyhepta-2,4-diend-1,7-dioate isomerase - Thermoplasma volcanium Length = 268 Score = 130 bits (315), Expect = 3e-29 Identities = 72/217 (33%), Positives = 113/217 (52%), Gaps = 7/217 (3%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128 P K+ +N++ H E P P+ F KF + +V N ++ + K + E Sbjct: 55 PAVNPQKIFLPAVNFRSHSAESDTRFPPKPYFFTKFSNALVANNSELRTPGTIKK-LDYE 113 Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW---EKNKKISQLLLGKAMDTFCP 185 E VIGKK + + A+D + G+TIA D+ A D+ E + + GKA D P Sbjct: 114 GETGAVIGKKCYNIPAEDAYDCIFGFTIANDLSARDFQFPEMHPYGYNWVQGKAFDGALP 173 Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 +GP+I T DEI P L ++ +NG +QK T+ + D+I+ LS +TL PGDII Sbjct: 174 VGPYITTKDEIQFP--LEIETKVNGETRQKGTTDDMVFSFQDLISTLSQNITLEPGDIIT 231 Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 +GTP GV + + +L+ GDVI + ++GT ++ Sbjct: 232 SGTPAGVAAF-SEKLYLKSGDVIEISVSSLGTLMNKI 267 >UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase-related protein; n=4; Deinococci|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase-related protein - Deinococcus radiodurans Length = 250 Score = 130 bits (314), Expect = 4e-29 Identities = 83/223 (37%), Positives = 117/223 (52%), Gaps = 17/223 (7%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPF---IFNKFPSTVVGPNDTIKL 117 LS L AP + K++CVG NY DH E +LP IF K P+ + P T++ Sbjct: 39 LSEARLLAPAEPS-KIVCVGRNYLDHIRELGNDTGDLPAEPGIFLKGPNALAEPGGTVEY 97 Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177 S+ E EL +VIG++A + + A VLGYT D+ A D +K Q Sbjct: 98 P-SWSENFHFEGELALVIGQRARNLKADEALGAVLGYTCGLDLTARDRQKTDL--QWFRA 154 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 KA D FCP+GPW+VT + P ++ V+ +NG +Q T+ I + I+ L+ +T Sbjct: 155 KAADRFCPLGPWLVTQFD---PSDVRVQTRVNGEPRQDGRTSHMIFDVVQILTYLTRFVT 211 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFET 280 L PGD++LTGTP GVG LQ GD + E++ IG ET Sbjct: 212 LEPGDVVLTGTPEGVGP-------LQRGDRVEVEVDGIGVLET 247 >UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family protein; n=8; Desulfuromonadales|Rep: Fumarylacetoacetate hydrolase family protein - Geobacter sulfurreducens Length = 218 Score = 130 bits (314), Expect = 4e-29 Identities = 71/211 (33%), Positives = 113/211 (53%), Gaps = 11/211 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K+LC+G NY +H +E P+ P +F K + V+G +TI + S+ E EL ++ Sbjct: 17 KILCIGRNYAEHIKELGNETPDAPVVFMKPATAVIGDGETIIIP-SYSRECHHEAELALL 75 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 192 IGK + A ++V GY +A D+ D E KK + K DT CP+ + V Sbjct: 76 IGKGGKDIPPERALEHVAGYGVAIDLTLRDVQAELKKKGLPWEIAKGFDTSCPLSSF-VP 134 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252 +D + +P +L++ +NG +Q +++ IH+IP I++ +S V TL PGD+ILTGTP GV Sbjct: 135 ADRVADPHDLHITLRVNGEMRQDGSSSLMIHRIPQILSYMSGVFTLEPGDVILTGTPAGV 194 Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 G L GD + +E+ + V+ Sbjct: 195 GP-------LAAGDAVEAEVVGVAAIRVTVK 218 >UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Archaeoglobus fulgidus|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Archaeoglobus fulgidus Length = 324 Score = 130 bits (314), Expect = 4e-29 Identities = 83/233 (35%), Positives = 126/233 (54%), Gaps = 15/233 (6%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHC----EEQKLTPPE----LPFIFNKFPSTVVGPN 112 LS + LKAP+ K++ +++H E+ ++ P+ +P + P +V+GP Sbjct: 93 LSEVKLKAPL--KPKLMVDFSTFEEHVRMGFEKLGMSIPQEWYQVPVGYKMNPYSVIGPE 150 Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNK-KI 171 + + + ++ + E+E +V+GK+ V A DYVLGYTI DI A D E + K Sbjct: 151 EPV-IWPSFTQILDYELEFGIVVGKRGKNVSKEDAMDYVLGYTIVNDISARDMEFIELKA 209 Query: 172 SQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDII 229 L L K D P+GP IVT DEI +P NL + +NG +++T KIPD+I Sbjct: 210 MPLGPLKSKDFDNATPMGPCIVTKDEIKDPHNLKMVARVNGEVWSEASTKDMHWKIPDLI 269 Query: 230 ARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 A LS T+ PG ++L+GTPGG G + + L+PGDV+ EIE IG + Sbjct: 270 AHLSKDQTIHPGTVMLSGTPGG-GCGMHVGKLLKPGDVVELEIEGIGVLRNPI 321 >UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albicans IPF5534 5-oxo-1; n=1; Debaryomyces hansenii|Rep: Similar to CA3735|IPF5534 Candida albicans IPF5534 5-oxo-1 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 289 Score = 129 bits (312), Expect = 7e-29 Identities = 78/224 (34%), Positives = 114/224 (50%), Gaps = 9/224 (4%) Query: 66 LKAPVHGNDK--VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 L P+ G D V C+G+NYK+H + PP P +F K ++V N+ I + + Sbjct: 67 LLGPLTGEDVPVVKCIGMNYKEHLMGI-IEPPPYPQLFYKPRTSVADQNEDIPIPLFAQN 125 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW----EKNKKISQLLLGKA 179 E EL VVIGK ++ A YV GY D+ A DW E K+ QL K+ Sbjct: 126 TCDYEGELCVVIGKTGKNINEEDALSYVAGYVSGNDLSARDWQYFPEYAGKVPQLGFSKS 185 Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 D + P+GP IV+S I +P L ++ ING +Q T+ + I IIA +S TL Sbjct: 186 FDRYAPLGPAIVSSKIIKDPHALQLQTRINGDLRQNCGTDDLLFGISRIIAFISQETTLE 245 Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 G +I+TGTP G G ++L+ GD++ I+ IGT + + Sbjct: 246 QGTVIMTGTPNGCGGIDG--KYLKDGDLVEVTIDQIGTLSHKTK 287 >UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Halorubrum lacusprofundi ATCC 49239 Length = 304 Score = 129 bits (312), Expect = 7e-29 Identities = 71/205 (34%), Positives = 109/205 (53%), Gaps = 12/205 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++C+G NY DH E P+ P +F K P+ + D I + + + E E+ VV Sbjct: 106 KIVCIGRNYADHAAELDNDVPDRPLLFLKPPNALASHGDEITVPAGKDR-IDWEAEIAVV 164 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IG++ VD+ A D V G+T D+ D + ++ + GKA D P+GP + T D Sbjct: 165 IGEQCKDVDADDAMDVVAGFTCMNDVSNRDDQDREQ--NWVRGKAFDGAAPLGPVMATPD 222 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 E+ P + +V+ +NG KQ S+ + + +P +I ++ +TL PGD+I TGTP GVG Sbjct: 223 EV--PADASVELRVNGETKQSSDRSYLMFDVPTLIEEITTYLTLEPGDVISTGTPEGVGA 280 Query: 255 YRNPPEFLQPGDVITSEIENIGTFE 279 L GD + EIE +GT E Sbjct: 281 -------LSDGDTVEVEIEGVGTLE 298 >UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Leptospirillum sp. Group II UBA|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Leptospirillum sp. Group II UBA Length = 267 Score = 128 bits (310), Expect = 1e-28 Identities = 80/217 (36%), Positives = 118/217 (54%), Gaps = 14/217 (6%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L + L PV K++ VGLNY+ H E PE P +F K S ++ PN I+L Sbjct: 47 LLDVRLHPPVTPG-KIIAVGLNYRAHGNEMGKPLPEEPLLFMKATSALLPPNGEIRLPR- 104 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 +S+ V E E+ +V+GKKAS + +V G T A D+ A D +K K Q K+ Sbjct: 105 MSRRVDFEGEIALVMGKKASGISPEEVPLFVYGITCANDVTARDLQK--KDVQYTRAKSF 162 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 DTFCP+GP I+T P + ++ +NGV +Q++ + I +++ +S VMTL P Sbjct: 163 DTFCPLGPVILTG---ALPDDRRLRTEVNGVVRQEARASDMIFDPLTLVSFISQVMTLEP 219 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGT 277 GD+ILTGTP GVG L P D ++ +E +G+ Sbjct: 220 GDVILTGTPSGVGP-------LSPMDRVSVSLEGVGS 249 >UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6; Pezizomycotina|Rep: RIB40 genomic DNA, SC005 - Aspergillus oryzae Length = 299 Score = 128 bits (308), Expect = 2e-28 Identities = 75/213 (35%), Positives = 109/213 (51%), Gaps = 9/213 (4%) Query: 78 CVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND--TIKLKMDVSKAVVCEIELTVVI 135 CVGLNY H +E PP PFIF K P+T V + + ++ + E EL ++I Sbjct: 85 CVGLNYAKHIKEAGRKPPPFPFIFFK-PNTCVHDHGKPVVIPRIAQNDQADYEGELCLII 143 Query: 136 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK----ISQLLLGKAMDTFCPIGPWIV 191 GK A V HA +YV YT DI + +++ + Q K DTF P+GP +V Sbjct: 144 GKDAKDVSPEHALEYVAAYTAGNDISSRKLQRDPAYAGVVPQWGFSKGFDTFAPLGPVLV 203 Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251 + EI +P L++K ++G +Q + +I+ LS TL G +I+TGTPGG Sbjct: 204 AASEIPDPSQLHLKTIVDGEVRQDETVGDLLFDCKYLISYLSQGTTLQKGSVIMTGTPGG 263 Query: 252 VGVYR--NPPEFLQPGDVITSEIENIGTFETRV 282 +GV PP++L PG + +I IGT V Sbjct: 264 LGVGAGFKPPKWLVPGTQMDVQISQIGTLRNNV 296 >UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Predicted 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Methanosphaera stadtmanae (strain DSM 3091) Length = 256 Score = 128 bits (308), Expect = 2e-28 Identities = 78/209 (37%), Positives = 112/209 (53%), Gaps = 16/209 (7%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128 P K++CVGLNYKDH +E + P+ P +F K ++V+ N I + + + E Sbjct: 58 PPTNPSKIVCVGLNYKDHAKELNMELPDEPLLFMKPSTSVISTNSAI-IYPSTTNMLDFE 116 Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188 EL +VI +K S D+ + YTI D+ A D + K Q K+ DTFCP GP Sbjct: 117 GELGIVILEKVSPCDNGTCN---VAYTIVNDVTARDLQS--KDGQWTRSKSYDTFCPCGP 171 Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248 +VT + NLN+K +N KQ+SNT I +++ +SN+MTL PGDII +GT Sbjct: 172 VVVTGID---SSNLNIKTMVNNDIKQESNTKNMIFSPLELVKYISNIMTLNPGDIIASGT 228 Query: 249 PGGVGVYRNPPEFLQPGDVITSEIENIGT 277 P GVG L GD + EI+ +G+ Sbjct: 229 PPGVG-------HLDVGDTVVVEIDEMGS 250 >UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Marinomonas sp. MWYL1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Marinomonas sp. MWYL1 Length = 245 Score = 127 bits (307), Expect = 3e-28 Identities = 73/212 (34%), Positives = 112/212 (52%), Gaps = 10/212 (4%) Query: 73 NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 132 N+K L L K E+ + PP+ P + K +T +G +IKL D AV L Sbjct: 43 NNKALAKSLE-KAFNEKPHVQPPKTPVLHIKTDNTHIGYGKSIKLPSDKG-AVFAGPSLG 100 Query: 133 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 192 +VIGKK ++VD+S+A D V G+T+ ++ + + + K DTFCPIGPW V Sbjct: 101 IVIGKKTTRVDASNALDCVAGFTVVNEVSLAETSFYRPAVK---AKCRDTFCPIGPWSVD 157 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252 + P L++K IN ++NT+Q I+ + +I++ +S+ MTL GDII+ GTP Sbjct: 158 KSAVSTPNKLSIKTFINDALVHETNTDQLIYSVEEIVSYISSFMTLEAGDIIIAGTP--- 214 Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 R + PGD + +IE +G VE+ Sbjct: 215 --ERTADLAINPGDSVMIDIEGVGRLVNPVEQ 244 >UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4; Actinomycetales|Rep: Maleylpyruvate isomerase - Rhodococcus sp. (strain RHA1) Length = 275 Score = 126 bits (305), Expect = 5e-28 Identities = 70/211 (33%), Positives = 111/211 (52%), Gaps = 5/211 (2%) Query: 68 APVHGND-KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV 126 APV N K++CVGLNY +H +E PE P +F KF + GP D + + + + Sbjct: 61 APVVPNPGKIICVGLNYANHIQEMGRDLPEYPTLFAKFKEALTGPYDDVIVPSYAAAQLD 120 Query: 127 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPI 186 E EL V+GK+A +V + A Y+ GY++ D D++ + Q GK + Sbjct: 121 WEGELAFVVGKQAYQVPEADAEQYIAGYSVMNDYTMRDYQ--YRTLQWDQGKTFEKTSGF 178 Query: 187 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 246 GP++ T+D L K + G Q + T+ + ++ +S+++TL PGD+++T Sbjct: 179 GPFLTTTDSYTFGGTLVTK--LEGQVVQSTTTDDLVFTPARLVEYISHIVTLQPGDVVIT 236 Query: 247 GTPGGVGVYRNPPEFLQPGDVITSEIENIGT 277 GTPGGVG R P ++Q G + IE +GT Sbjct: 237 GTPGGVGHARKPGLYIQDGQTVEVTIEGLGT 267 >UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14; Dikarya|Rep: Mitochondrion protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 311 Score = 126 bits (303), Expect = 8e-28 Identities = 77/214 (35%), Positives = 114/214 (53%), Gaps = 8/214 (3%) Query: 76 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVG---PNDTIKLKMDV-SKAVVCEIEL 131 + C+GLNY +H +E L P++P +F K PST + P+ TI K V S + E E+ Sbjct: 99 IRCIGLNYVNHAKEVNLPMPDIPTLFMK-PSTSLADPFPSPTIIPKAFVASNSADFESEV 157 Query: 132 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 191 VIGK A V A DYVLG+T A D+ + + + + SQ K+ D CPIGP +V Sbjct: 158 AFVIGKDAKNVSEEEALDYVLGFTAANDVSSREAQFAQ--SQWCYSKSFDGACPIGPALV 215 Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251 ++ ++ ++ S+NG Q S + I +P I++ LS TL G II+TGTP G Sbjct: 216 NKNQANKFSDVKIEGSLNGKTVQSSRLDDLIFSVPKIVSFLSQGTTLPAGTIIITGTPAG 275 Query: 252 VGVYRNPPEFLQPGDVITSEIEN-IGTFETRVEE 284 VG P L+ GD + + +GT ++ E Sbjct: 276 VGWSSTPRITLKDGDEFRVFVSHGVGTLINKIVE 309 >UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3; Eukaryota|Rep: Mitochondrion protein, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 228 Score = 126 bits (303), Expect = 8e-28 Identities = 71/183 (38%), Positives = 104/183 (56%), Gaps = 8/183 (4%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC--EIELT 132 K++ +G NY DH +E P+ PF F K S+ + P++ +++ + V+ E+EL Sbjct: 10 KIVAIGRNYADHAKELGNAIPKEPFFFLKPTSSYLVPDNG---PVEIPRGVIVHHEVELG 66 Query: 133 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWI 190 VVIGK + S AFD+V GY++A D+ A + + K L K DTFCPIGP+I Sbjct: 67 VVIGKNGRDISPSAAFDHVAGYSLAVDMTARNVQDKAKAKGLPWSAAKGFDTFCPIGPFI 126 Query: 191 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 250 I +P + + S+NG KQ T+ I IP +IA +S +M L GD++LTGTP Sbjct: 127 -PKHFIADPTKVGLHFSVNGTVKQSGLTSDMIFDIPQLIAFVSGIMKLEEGDLVLTGTPS 185 Query: 251 GVG 253 GVG Sbjct: 186 GVG 188 >UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Bacillus coagulans 36D1|Rep: Fumarylacetoacetate (FAA) hydrolase - Bacillus coagulans 36D1 Length = 278 Score = 125 bits (302), Expect = 1e-27 Identities = 85/228 (37%), Positives = 107/228 (46%), Gaps = 20/228 (8%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELP------FIFNKFPSTVVGPNDT 114 L+G+TLK PV G K+ +NY H EE P +F K P ++ GP D Sbjct: 63 LNGVTLKCPVPGAGKIWAAPVNYLKHQEEMNHQFNNAPRTIEELSLFLKSPQSLSGPTDP 122 Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174 I L + E EL ++GKKA V + A DY+ GY DI E+ Sbjct: 123 IILPFP-ERRTDHEAELGYIVGKKAKNVKAREAKDYIFGYFALLDISIRGNEERT----- 176 Query: 175 LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSN 234 K+ DTF PIGPWIVT DEI NP +L + +N +Q +T I+ + Sbjct: 177 -WRKSFDTFTPIGPWIVTEDEIKNPNDLAISLWVNDELRQSGSTKYLIYDCYKCFELACD 235 Query: 235 VMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 MTL PGDII TGTP GVG R GD + IE IG F V Sbjct: 236 HMTLHPGDIIATGTPEGVGPIRE-------GDRVKISIEQIGEFTVDV 276 >UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5; Eukaryota|Rep: Uncharacterized protein ZK688.3 - Caenorhabditis elegans Length = 214 Score = 125 bits (302), Expect = 1e-27 Identities = 70/180 (38%), Positives = 101/180 (56%), Gaps = 4/180 (2%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++CVG NYKDH E P+ P +F K ++ + + I + E+EL VV Sbjct: 13 KIVCVGRNYKDHALELGNAIPKKPMLFVKTVNSFIVEGEPIVAPPGCQN-LHQEVELGVV 71 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 192 I KKAS++ S A DY+ GYT+A D+ A D+ E K + L K+ D CPIG ++ Sbjct: 72 ISKKASRISKSDAMDYIGGYTVALDMTARDFQDEAKKAGAPWFLAKSFDGSCPIGGFLPV 131 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252 SD I NP ++ + C ING +Q+ T+ I IP ++ + TL GD++LTGTP GV Sbjct: 132 SD-IPNPHDVELFCKINGKDQQRCRTDVMIFDIPTLLEYTTQFFTLEVGDVVLTGTPAGV 190 >UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM - Pseudomonas abietaniphila Length = 289 Score = 125 bits (301), Expect = 1e-27 Identities = 78/229 (34%), Positives = 118/229 (51%), Gaps = 11/229 (4%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 LS +TL P+ ++V+ G NY H E L+ P P F K ++G +D I+ Sbjct: 57 LSQVTLLPPIEPVNRVVVAGANYAKHLVEFGLSAPSQPVAFLKAYGALIGAHDPIRFP-P 115 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN--KKIS-QLLLG 177 ++ + E+EL VIG + VD VLGYT+ D+ A D +++ K I L Sbjct: 116 LTTELDHEVELVAVIG--SDDVDLDDPLACVLGYTVGNDVSARDLQRSGPKGIGMDLFAA 173 Query: 178 KAMDTFCPIGPWIVTSDEI--GNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNV 235 K+ D +GPW+VT DE+ G+P+ L + +NG +Q NT + ++IA + Sbjct: 174 KSQDKTTGLGPWVVTKDELPEGSPK-LRLTLKVNGQMRQDGNTADMTWDVGELIAFVQQR 232 Query: 236 MTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 + GD++ TG+P GVG+ FL PGDV+ + IE IGT V E Sbjct: 233 SSFACGDVLFTGSPAGVGM--GTGIFLDPGDVVEASIEGIGTLRNVVGE 279 >UniRef50_Q4JXJ3 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Corynebacterium jeikeium K411|Rep: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Corynebacterium jeikeium (strain K411) Length = 272 Score = 124 bits (299), Expect = 3e-27 Identities = 67/209 (32%), Positives = 108/209 (51%), Gaps = 13/209 (6%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K+ CVGLNY++H E P+ P +F K+ S + GP D + + ++S E EL V+ Sbjct: 74 KIFCVGLNYREHIAEMGHPIPDHPTLFVKYASALAGPFDEVVVPPELSAQADYEGELAVI 133 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 +G+ F + GYT+ D DW+ + Q L GK +D GPW+V ++ Sbjct: 134 MGE----------FGQIAGYTVMNDFSQRDWQY--RTQQWLQGKNLDRSSGFGPWMVPTE 181 Query: 195 EIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 + ++ +NG +Q+ + + K D++ +SN +L PGD+I+TGTP GVG Sbjct: 182 HFDPIAEGAVLRTWVNGELRQEHSVADLVFKPQDLVDYISNFASLAPGDVIVTGTPEGVG 241 Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRV 282 PP++L GD + I+ IG R+ Sbjct: 242 HGMTPPQYLADGDEVRIAIDGIGEICNRI 270 >UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase; n=2; Ostreococcus|Rep: Predicted fumarylacetoacetate hydralase - Ostreococcus tauri Length = 322 Score = 124 bits (299), Expect = 3e-27 Identities = 77/223 (34%), Positives = 116/223 (52%), Gaps = 18/223 (8%) Query: 76 VLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 127 + CVG NY +H E ++ PE P IF+K +++ +I + K V Sbjct: 102 IACVGKNYLEHVGEVDSTMPGISRMDVPEAPIIFSKASTSLNAHLGSIATRG--RKDVDY 159 Query: 128 EIELTVVIGKKASKVDSSHAFD-----YVLGYTIAQDIGATDWEKNKKISQLLLGKAMDT 182 E EL VIG++ +D + + YV+G++IA D+ A + +K + Q LGK+ DT Sbjct: 160 EGELVAVIGRECRDIDPGMSDEDVVKNYVIGWSIANDVTARELQKTHQ--QWFLGKSGDT 217 Query: 183 FCPIGPWIVTSDEIGNPQNL-NVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241 CP+GPW+ D ++ ++N +Q+S +Q I + +IA +S TL G Sbjct: 218 HCPLGPWVCCDDGRAPALGAASITTAVNSEIRQRSTVDQLIWSVGALIACISRHQTLRVG 277 Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 D +LTGTP GVG +PP FLQPGD IE +GT + V E Sbjct: 278 DCVLTGTPSGVGAGFDPPRFLQPGDACEVTIEGVGTLKNTVVE 320 >UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6; Ascomycota|Rep: 2-keto-4-pentenoate hydratase - Sclerotinia sclerotiorum 1980 Length = 241 Score = 123 bits (297), Expect = 5e-27 Identities = 72/227 (31%), Positives = 122/227 (53%), Gaps = 8/227 (3%) Query: 63 GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122 G+ +P KV+C+G NY DH E + P+ PF F K PS+++ PN ++ Sbjct: 8 GLATVSPFKSASKVVCIGRNYADHITELNNSKPKQPFFFLKPPSSILPPNGGAVIRPK-G 66 Query: 123 KAVVCEIELTVVIGKKASKVDSSH---AFDYVLGYTIAQDIGATDWEKNKKISQLL--LG 177 + E+EL +++GK+ ++ + A+D + Y ++ D+ A + + K L + Sbjct: 67 VDLHYEVELALIMGKQLKNLEPENEKEAYDSIESYAMSIDMTARNAQNEAKKKGLPWDIA 126 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 K DTF P+ I++ +I +P N V ++N +QK +T +++IP I++ +S VMT Sbjct: 127 KGFDTFLPMSN-IISKSQIPDPHNATVWLTVNNEHRQKDSTELMLYRIPRILSDISKVMT 185 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 L GDI+LTGTP GVG + P + ++ G + + G E VEE Sbjct: 186 LEKGDIVLTGTPKGVGSVK-PGDVMRVGISVGGKELTEGKIEVAVEE 231 >UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation bifunctional isomerase : decarboxylase; n=2; Bacillaceae|Rep: 4-hydroxyphenylacetate degradation bifunctional isomerase : decarboxylase - Oceanobacillus iheyensis Length = 263 Score = 122 bits (294), Expect = 1e-26 Identities = 79/232 (34%), Positives = 116/232 (50%), Gaps = 21/232 (9%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHC--------EEQKLTPPELPFIFNKFPSTVVGPN 112 L ++L P++G V LNYK E+ TPP+ P ++ K +T +G Sbjct: 35 LDDLSLDVPINGT--VYGTLLNYKGEYAELESSMNEDPYKTPPKAPILYIKPINTHIGYG 92 Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS 172 TI L V K + L VVIGK A + +A DYV GYTI D+ + + Sbjct: 93 MTIPLPEGVEKVSI-GAALGVVIGKPAKNIRKENALDYVAGYTIVNDVSIPNESYYRPAY 151 Query: 173 QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 232 + KA D FCPIGPW++ D I NP L ++ ING KQ++ T+ I + ++ + Sbjct: 152 K---EKARDGFCPIGPWVLRRDAIENPNELGIRVYINGEIKQENTTSNLIRSVEQLMEEV 208 Query: 233 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 ++ MTL GD++L G P N P + D + EI+NIGT +VE+ Sbjct: 209 TDFMTLYEGDVLLVGVP------ENAP-IAKENDRVIIEIDNIGTLVNKVEK 253 >UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Serratia proteamaculans 568 Length = 287 Score = 122 bits (293), Expect = 1e-26 Identities = 79/234 (33%), Positives = 117/234 (50%), Gaps = 24/234 (10%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEE----QKLTPPELPF------IFNKFPSTVVG 110 L ++L APV K++ +NY+DH E Q++ ++ +F K S++ G Sbjct: 65 LEQVSLNAPVANPGKIVAAPINYRDHIAEANADQQINHGKVYTDISEYGLFLKANSSLCG 124 Query: 111 PNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK 170 PN+ I L + + E+EL V+IG++A + A + V GY I D+ E Sbjct: 125 PNEIIPLPIP-GRRTDPEVELAVIIGQRARNLPVDQALEAVFGYAIGIDMTVRGSEFPS- 182 Query: 171 ISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIA 230 K+ D F +GPWIVT DEIG+P L++ +NG +Q SNT I+ + +IA Sbjct: 183 -----FRKSADGFSVLGPWIVTPDEIGDPNTLDLSIRVNGQLRQHSNTRHLIYNVQRLIA 237 Query: 231 RLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 S + TL PGD+I TGTP GV +Q GD I IE IG + + Sbjct: 238 YASAMFTLWPGDVIYTGTPSGVSA-------IQAGDRIEVSIERIGAMSVTIAD 284 >UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albicans IPF5534; n=2; Ascomycota|Rep: Similar to CA3735|IPF5534 Candida albicans IPF5534 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 208 Score = 121 bits (292), Expect = 2e-26 Identities = 74/208 (35%), Positives = 105/208 (50%), Gaps = 9/208 (4%) Query: 81 LNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKL-KMDVSKAVVCEIELTVVIGKK 138 +NY H +E L PP P IF K P T VG N+ I + K+ E E VVI K Sbjct: 1 MNYMKHIQEGSLPPPPKPQIFYK-PRTSVGDHNEAIAIPKIAQENQCDYEGEFCVVIVKT 59 Query: 139 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNK----KISQLLLGKAMDTFCPIGPWIVTSD 194 + A +YV GY + D+ A W+ + I Q K+ D + P+GP + ++ Sbjct: 60 GKHIKEEDALNYVAGYIVGDDVSARIWQYHPDYSGNIPQWYYSKSFDRYAPLGPALFSTR 119 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 I NP L ++ ING +Q +NT+ + I IIA LS TL G +I+TGTP GVG Sbjct: 120 VIKNPHTLQLQTRINGELRQDANTDDLLFNIQKIIAFLSQGTTLEQGTVIMTGTPSGVGA 179 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282 +L+ GD++ IE IGT ++ Sbjct: 180 VSG--RYLKDGDLVEISIEQIGTLSHKI 205 >UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Gammaproteobacteria|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - marine gamma proteobacterium HTCC2143 Length = 223 Score = 120 bits (290), Expect = 3e-26 Identities = 75/210 (35%), Positives = 107/210 (50%), Gaps = 12/210 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++CVG NY DH +E P+ P +F K + V I + D E+E+ V+ Sbjct: 23 KIVCVGRNYADHAKELNNPIPDRPLLFIKPSTAAVDMLLPINIPTDRG-CCHHELEMAVL 81 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 192 IGK++S V S A D ++G + D+ D + K KA D CP+ P+ Sbjct: 82 IGKRSSSVSSVEAKDAIVGVGLGLDLTLRDLQDELKAKGEPWERAKAFDGSCPLSPFSSV 141 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252 D + QNLN+ NG +Q NT + + D+IA +S TLLPGDIILTGTP GV Sbjct: 142 GDI--DQQNLNITLLRNGTVQQSGNTRDMLFPVADLIADISRSFTLLPGDIILTGTPAGV 199 Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRV 282 G L PGD IT+++ ++ T T + Sbjct: 200 GP-------LYPGDTITAQLGDLVTVNTTI 222 >UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41; Gammaproteobacteria|Rep: Uncharacterized protein ycgM - Escherichia coli (strain K12) Length = 219 Score = 119 bits (287), Expect = 7e-26 Identities = 72/200 (36%), Positives = 102/200 (51%), Gaps = 6/200 (3%) Query: 63 GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122 G L PV KV+CVG NY H +E PE P +F K + + + + D Sbjct: 9 GALLDYPV---SKVVCVGSNYAKHIKEMGSAVPEEPVLFIKPETALCDLRQPLAIPSDFG 65 Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLL-LGKAM 180 +V E+EL V+IG + H + GY +A D+ D + K KK Q KA Sbjct: 66 -SVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWEKAKAF 124 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 D CP+ +I ++ G+PQN + S+NG Q+Q+ T IHKI +IA +S TL Sbjct: 125 DNSCPLSGFIPAAEFTGDPQNTTLSLSVNGEQRQQGTTADMIHKIVPLIAYMSKFFTLKA 184 Query: 241 GDIILTGTPGGVGVYRNPPE 260 GD++LTGTP GVG ++ E Sbjct: 185 GDVVLTGTPDGVGPLQSGDE 204 >UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1; Helicobacter hepaticus|Rep: Putative uncharacterized protein - Helicobacter hepaticus Length = 312 Score = 118 bits (284), Expect = 2e-25 Identities = 78/234 (33%), Positives = 121/234 (51%), Gaps = 12/234 (5%) Query: 61 LSGITLKAPV-HGNDKVLCVGLNYKDHCEEQKLTPPEL-------PFIFNKFPSTVVGPN 112 L+ ITL AP+ V+C+G+NY +H +E E+ F+K + N Sbjct: 82 LADITLLAPIPKPKQDVICLGINYLEHAKESAAYKNEIFDQKRENAVYFSKRVNYATPHN 141 Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKNKKI 171 I L ++++ + E+EL VV+G K + D + GYTI DI + D ++ K Sbjct: 142 APIPLHSNLTQKLDYEVELGVVLGSHLYKPKNMQEVIDSIFGYTIINDISSRDIQQKHK- 200 Query: 172 SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIAR 231 Q +GK+++ P+GP IV++ I + QNL +K +NG +Q S+T+ I I + Sbjct: 201 -QWYMGKSLEGSLPMGPCIVSARSI-DAQNLAIKSYVNGELRQDSHTSLMICNITAALYE 258 Query: 232 LSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285 LS+ L II GTP GVG+ NPP FL D I EI++IG+ V ++ Sbjct: 259 LSHYCMLQAASIISMGTPSGVGMGFNPPRFLSNNDEIVCEIQHIGSLRNVVIDY 312 >UniRef50_Q2S2N6 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Salinibacter ruber DSM 13855|Rep: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Salinibacter ruber (strain DSM 13855) Length = 220 Score = 118 bits (284), Expect = 2e-25 Identities = 62/189 (32%), Positives = 103/189 (54%), Gaps = 4/189 (2%) Query: 67 KAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV 126 ++P K+LC+G NY DH E P+ P +F K S +V ++L S+ V Sbjct: 8 RSPPVSVGKLLCIGRNYADHAAEMDRAVPDEPMVFLKPASALVRSGGAVRLPPQ-SQDVH 66 Query: 127 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ--LLLGKAMDTFC 184 E+EL V+G + + S A D+V GY + D+ A D + K + + K DTF Sbjct: 67 HEVELVAVVGTEGKNIPRSAALDHVAGYAVGLDMTARDLQAEAKERRHPWSVAKGFDTFA 126 Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244 P+GP I ++ + + Q+L ++ ++N +Q+++T I + D++ S++ TL PGD++ Sbjct: 127 PLGP-IQPAEAVDDVQDLTLRLTVNDETRQEASTRHQIFPVRDLVHYCSHIFTLSPGDLL 185 Query: 245 LTGTPGGVG 253 TGTP GVG Sbjct: 186 YTGTPSGVG 194 >UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=2; Gammaproteobacteria|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Enterobacter sp. 638 Length = 219 Score = 118 bits (284), Expect = 2e-25 Identities = 73/193 (37%), Positives = 99/193 (51%), Gaps = 6/193 (3%) Query: 63 GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122 G L PV KV+CVG NY H +E P+ P +F K + + + L + Sbjct: 9 GALLDYPV---SKVVCVGSNYAKHIQEMGSAVPDEPVLFIKPETALCDIRQPLALPQGLG 65 Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLL-LGKAM 180 +V E+EL V+IG + H + GY IA D+ D + K KK Q K Sbjct: 66 -SVHHEVELAVLIGATLRQASEEHVQKAIAGYGIALDLTLRDVQGKMKKAGQPWEKAKGF 124 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 D CPI +I T+D +PQN ++ +NG +Q+ NT IHKI +IA +S TL P Sbjct: 125 DNSCPISGFIPTADFKADPQNTSLSLKVNGDIRQQGNTADMIHKILPLIAYMSRYFTLKP 184 Query: 241 GDIILTGTPGGVG 253 GD+ILTGTP GVG Sbjct: 185 GDVILTGTPEGVG 197 >UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomer; n=10; Bacteria|Rep: 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomer - Synechocystis sp. (strain PCC 6803) Length = 276 Score = 118 bits (283), Expect = 2e-25 Identities = 72/208 (34%), Positives = 101/208 (48%), Gaps = 12/208 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++ VG NY+ H E P P +F K PS + + I S+ V E EL V+ Sbjct: 59 KIVAVGRNYRAHAAELGNDVPAEPLLFFKPPSAIAADQEEIVYPSQ-SQRVDYEGELAVI 117 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IGK+ + A + GYTIA DI A D ++ SQ K D FCP+GPW+V Sbjct: 118 IGKQVKDITEEEAASAIWGYTIANDITARDLQRQD--SQWTRAKGFDGFCPLGPWVVR-- 173 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 I +L + +Q + + + P +++ +S VMTL PGD+ILTGTP G+ Sbjct: 174 HIDPEAHLETTVNDEETPRQATAISDMVFTPPVLVSYISRVMTLYPGDVILTGTPEGISA 233 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282 LQ GD + EIE IG + Sbjct: 234 -------LQVGDKVEVEIEGIGNLTNTI 254 >UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 343 Score = 117 bits (282), Expect = 3e-25 Identities = 73/188 (38%), Positives = 99/188 (52%), Gaps = 7/188 (3%) Query: 98 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 157 PF F K S+++GP D + + D S+ + E+EL VVIGK A +V A D+V GY + Sbjct: 137 PFAFLKPFSSILGPFDDLAVPAD-SEQLDWELELGVVIGKPARRVGRDRALDHVAGYVVV 195 Query: 158 QDIGATDWEKNKKISQLLL----GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213 DI D + QL L GK+ P+GP IV + + +PQ L + +NG Sbjct: 196 NDISVRDHLYRPDVPQLGLDWVSGKSGPGMLPMGPLIVPAAFVADPQQLMITLKLNGEVM 255 Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273 Q +T I I +I S M LLPGDII TG+P G G + FL+PGDV+ IE Sbjct: 256 QHESTADMIFPIARLIEAFSVHMQLLPGDIICTGSPSGNGTHFG--RFLRPGDVMEGTIE 313 Query: 274 NIGTFETR 281 +GT R Sbjct: 314 GLGTQRNR 321 >UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Corynebacterium|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 268 Score = 116 bits (280), Expect = 5e-25 Identities = 85/222 (38%), Positives = 114/222 (51%), Gaps = 17/222 (7%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEE--QKLTPPELPFIFNKFPSTVVGPNDTIKLK 118 L + L AP+ + KV+ +G NY DH E +K P +F K P+ V GP I++ Sbjct: 49 LKDVRLLAPMLPS-KVVAIGRNYADHVAEVFKKSAESLPPTLFLKPPTAVTGPESPIRIP 107 Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGK 178 +K V E EL VVIGK V + VLG+TI D+ + D + Q K Sbjct: 108 SFATK-VEFEGELAVVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFAD--GQWARAK 164 Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCSI--NGVQ--KQKSNTNQFIHKIPDIIARLSN 234 +DTF PIGPWI T + NL +K + +G KQ SN+NQ I K+ +II ++ Sbjct: 165 GIDTFGPIGPWIETDINSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFITA 224 Query: 235 VMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 MTLLPGD+I TG+P G E + GD I EI IG Sbjct: 225 SMTLLPGDVIATGSPAGT-------EAMVDGDYIEIEIPGIG 259 >UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 255 Score = 116 bits (279), Expect = 7e-25 Identities = 84/222 (37%), Positives = 112/222 (50%), Gaps = 14/222 (6%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 L + L +PV KV+ +G NY D P P IF K ++VVGP+D I + Sbjct: 45 LDEVRLLSPVIPRSKVVGIGDNYSDTPIPADERPE--PPIFLKANTSVVGPDDPIAIPA- 101 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 S AV E EL +VI A V A +LGYTIA D A D S+ GK+ Sbjct: 102 WSNAVAFEGELAIVIKSLAKDVSVEDAPQMILGYTIANDATARDAMTGGPWSR---GKSF 158 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 D+ CP+GPWI T D + NL ++ +NG Q S+T I ++++ LS+ MTLLP Sbjct: 159 DSACPLGPWI-TVDPALDVTNLAIRSYLNGEIAQDSSTAHMIWNPFELVSYLSHQMTLLP 217 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GD+I TG P G E + GD + EIE IG+ V Sbjct: 218 GDVIATGAPAGA-------EIVHAGDRVEIEIEGIGSLTNPV 252 >UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3; Trichocomaceae|Rep: Remark: ORF contains 1 frameshift - Aspergillus niger Length = 296 Score = 115 bits (276), Expect = 2e-24 Identities = 67/215 (31%), Positives = 110/215 (51%), Gaps = 5/215 (2%) Query: 73 NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKL-KMDVSKAVVCEI-E 130 N+ + CVGLNY+ H +E L P P ++ K P+ + P++TI + + S E E Sbjct: 64 NNSIYCVGLNYRSHAKEANLNVPANPPVWTKPPAALASPDETIPISRFCASHLPDWEAGE 123 Query: 131 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLLLGKAMDTFCPIGPW 189 L V ++ V A Y+LGYT+ D+ ++ + Q KA D F PIGP Sbjct: 124 LVFVTSRECRDVTPEQASQYILGYTVGNDLSCRFFQLPEQSGGQFFYAKAFDKFAPIGPV 183 Query: 190 IVTSDEIGNPQ-NLNVKCSINGVQKQKSNTNQFIHKIPD-IIARLSNVMTLLPGDIILTG 247 +V+ D + + + INGV KQ + + + P+ +++ +S T+ +++TG Sbjct: 184 LVSPDVFAKTRTSATLVTRINGVVKQDTVIGKDMIFSPERVLSWMSQSTTIPAYTVVMTG 243 Query: 248 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TP G GV++ P + L+ GD I EI +GT + V Sbjct: 244 TPAGAGVFQTPRQLLKDGDHIEVEISGLGTLKNVV 278 >UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Solibacter usitatus Ellin6076|Rep: Fumarylacetoacetate (FAA) hydrolase - Solibacter usitatus (strain Ellin6076) Length = 252 Score = 114 bits (275), Expect = 2e-24 Identities = 77/223 (34%), Positives = 106/223 (47%), Gaps = 15/223 (6%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 LS + L P K+L VGLNYK H + P P +F K S + P D I+L D Sbjct: 43 LSDVKLLYPCEAG-KILAVGLNYKSHLGSRP--QPAHPEMFYKPISALQNPGDPIELPRD 99 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLLLGKA 179 + V E E+ VV+G A D V G T D+ W+ KK Q K Sbjct: 100 ATD-VHSEGEMVVVVGGYLRNASVDEAADAVFGVTCGNDVSDRSWQHGEKKDLQWWRAKG 158 Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 DTF P+GP IV+ + G L ++ ING QK T+ I IP +++ +S +TL Sbjct: 159 SDTFAPLGPAIVSGVDYGK---LLLQTRINGETVQKQFTSDLIFDIPTVLSWISGWVTLF 215 Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 PGD++ TGTPG + PGD++ E+E +G V Sbjct: 216 PGDLVYTGTPGNT-------RKMSPGDLVEVELEGVGVLSNPV 251 >UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase domain-containing protein 1; n=21; Eumetazoa|Rep: Fumarylacetoacetate hydrolase domain-containing protein 1 - Homo sapiens (Human) Length = 224 Score = 114 bits (275), Expect = 2e-24 Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 4/187 (2%) Query: 76 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 135 ++CVG NY DH E + P +F K PST P + L ++ + E+EL VV+ Sbjct: 20 IVCVGRNYADHVREMRSAVLSEPVLFLK-PSTAYAPEGSPILMPAYTRNLHHELELGVVM 78 Query: 136 GKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVTS 193 GK+ V + A DYV GY + D+ A D E KK L K+ CP+ + V Sbjct: 79 GKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWTLAKSFTASCPVSAF-VPK 137 Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 ++I +P L + +NG +Q+ T+ I IP II+ +S ++TL GDIILTGTP GVG Sbjct: 138 EKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEEGDIILTGTPKGVG 197 Query: 254 VYRNPPE 260 + E Sbjct: 198 PVKENDE 204 >UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Caulobacter sp. K31|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Caulobacter sp. K31 Length = 293 Score = 113 bits (273), Expect = 4e-24 Identities = 79/283 (27%), Positives = 124/283 (43%), Gaps = 12/283 (4%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX 60 M+LL F + + G G+ V+D+ P LP + LL Sbjct: 1 MRLLSFELNGAPAV--GVRLGEEVIDLGAAAPDLPRDIQALLAAGPEALAAAERAAAAAP 58 Query: 61 ------LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT 114 L+G+ P+ DK++ +G Y H E K P +F + P ++V N Sbjct: 59 GHARHPLAGVRHLVPIPRPDKIIGLGKTYMKHVAEMKAESSSFPGMFLRVPDSLVAHNQP 118 Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174 I + + S + E EL VVIG+ + +A +V GY D + N S + Sbjct: 119 I-WRPEASDTLDYEGELMVVIGQGGRMISRENALKHVAGYACHNDGSVRAY--NYIPSAV 175 Query: 175 LLGKAMDTFCPIGPWIVTSDEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233 GK GP IVT+DE+ + L + +NG +Q ++ + + ++ +S Sbjct: 176 TAGKNFLNTGGFGPEIVTADELPPGCKGLRLTTHVNGDLRQSADVAELHWDVAHLVHLMS 235 Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 + TL PGD+I TGTP G P++L PGDV+ EIE +G Sbjct: 236 TIFTLYPGDLIATGTPSGCAAASANPQWLVPGDVVRVEIEGVG 278 >UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Silicibacter pomeroyi|Rep: Fumarylacetoacetate hydrolase family protein - Silicibacter pomeroyi Length = 281 Score = 113 bits (271), Expect = 6e-24 Identities = 64/225 (28%), Positives = 108/225 (48%), Gaps = 7/225 (3%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFI--FNKFPSTVVGPNDTIKLK 118 L + P+ K+LC G+NY+ + PP+ + F++ P T+VG +++ Sbjct: 58 LDSLVWLPPIPAPGKILCAGMNYRKPYPVAGVAPPDPGHVVLFSRHPQTLVGHGAMLEMP 117 Query: 119 MDVS-KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177 + ++ E E+ VIG+ + A +VLGY+ + W K+ + G Sbjct: 118 QGAAAESFDFEGEIVAVIGQPGRHIAPEAALGHVLGYSAMNEGSVRGWMKHS----VHAG 173 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 K GPWI T+DE G+ + ++ +NG Q + I + ++IA +S++ Sbjct: 174 KNFHASGSWGPWITTADEAGDIAGMTLETRVNGTPMQSDSGAGMIFGLAELIAYISHIQP 233 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 L GDII TG+P G G R PP FL+ GD + + +GT + V Sbjct: 234 LEAGDIIATGSPDGTGGSRTPPAFLRSGDRVAVTVGGVGTLKNTV 278 >UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=1; Jannaschia sp. CCS1|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Jannaschia sp. (strain CCS1) Length = 271 Score = 112 bits (270), Expect = 8e-24 Identities = 73/226 (32%), Positives = 110/226 (48%), Gaps = 10/226 (4%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 +T PV K+LCV LNY DH +E PE P +F K ++ I+ +++ Sbjct: 48 VTALPPVTPTAKILCVALNYVDHAKEANQPVPETPIVFFKTFDAMIAGGAPIRAPRMITQ 107 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK--ISQL--LLGKA 179 + E EL ++IGK+ + + A+D++ G T D+ A D K K S L GK Sbjct: 108 -LDYEGELALIIGKRGFDIAKTDAWDHIAGVTTLNDVSARDIFKVKAGAASHLDWFSGKC 166 Query: 180 MDTFCPIGPWIVTSDEIGNPQNLN---VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236 ++ PIGP + I + ++C +NG +Q + I IP +IA +S+ + Sbjct: 167 LNQSTPIGPEVFPLSAIEDDLKAGTTRIRCLVNGEVRQDAPVADMIFDIPTMIAFISSRI 226 Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 L PGDII TGTP GVG +L GDV+ E+ + E V Sbjct: 227 PLNPGDIIATGTPPGVGA--GTDRYLSKGDVVRVEVTGLPPMENTV 270 >UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate (FAA) hydrolase - Sphingomonas wittichii RW1 Length = 329 Score = 112 bits (269), Expect = 1e-23 Identities = 66/190 (34%), Positives = 96/190 (50%), Gaps = 7/190 (3%) Query: 98 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 157 P++F K +TV G NDT+ L + +K E+EL VVIG+ ++ A ++V GY I Sbjct: 139 PYVFTKPITTVAGANDTLILPANTTKPD-WELELAVVIGRGGIRIPREAAMEHVAGYAIV 197 Query: 158 QDIGATDWEKNKKISQL----LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213 D+ A D L L K + F P GP++V + I +P L ++ S+ G Sbjct: 198 NDVSARDLIPRTDYKLLGTDWLRSKGQEGFLPFGPYMVPARFIADPYALRIRLSVEGQMM 257 Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273 Q T + I I +S LLPGD+I TG+P G G + N FLQ GD++ EI+ Sbjct: 258 QDETTADMMFDIARQIEYISRYSRLLPGDVICTGSPAGNGTHYN--RFLQDGDLMIGEID 315 Query: 274 NIGTFETRVE 283 +G R E Sbjct: 316 GLGAQRIRCE 325 >UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep: Isomerase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 224 Score = 111 bits (268), Expect = 1e-23 Identities = 66/181 (36%), Positives = 102/181 (56%), Gaps = 4/181 (2%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++ VGLNY H +E P+ P +F K S+ + TI++ + ++ E+EL VV Sbjct: 15 KIVGVGLNYASHAKELGNALPKDPIVFLKPTSSYLENGGTIEIPHPLD-SLHHEVELAVV 73 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVT 192 IG+KA V A +Y+ GY +A D+ A + + + S L L K DTF PI ++ Sbjct: 74 IGQKARDVPERLAMNYIGGYALALDMTARELQVSAMASGLPCTLAKGQDTFTPISS-VLP 132 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252 + +P NL + ++ +QK T I K+P +I+ +S+VMTL GD+ILTGTP G+ Sbjct: 133 KAMVLDPNNLELWLKVDDETRQKGWTKDMIFKVPYLISYISSVMTLFKGDVILTGTPEGI 192 Query: 253 G 253 G Sbjct: 193 G 193 >UniRef50_Q8G4X7 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the fumarylacetoacetate hydrolase family; n=6; Bifidobacterium|Rep: Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the fumarylacetoacetate hydrolase family - Bifidobacterium longum Length = 292 Score = 111 bits (267), Expect = 2e-23 Identities = 79/223 (35%), Positives = 112/223 (50%), Gaps = 21/223 (9%) Query: 63 GITLKAPVHGNDKVLCVGLNYKDHCE-------EQKLTPPELPFIFNKFPSTVVGPNDTI 115 GI L +PV + KV + NY+ H + + PE IF K ++V+GP+D I Sbjct: 73 GIRLLSPVIPS-KVYGLAKNYEAHAQFMHEAGHSEIAHAPEDMVIFTKPSTSVIGPDDPI 131 Query: 116 KLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL 175 SK + E E+ VV+G+ A V +A DYVLG+T D+ D + Sbjct: 132 VYPA-CSKDMNFEPEVAVVMGRIAKNVTVENAMDYVLGFTCVNDVTLRDLQGIDPT--WT 188 Query: 176 LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSING--VQKQKSNTNQFIHKIPDIIARLS 233 K DT CP+GPWIV D++ + ++ + ++NG V T IH IP+ IA +S Sbjct: 189 RAKGFDTSCPLGPWIVMRDDL-DWKDAKISFTLNGEDVPMASGTTANLIHGIPEQIAAIS 247 Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 + TLLPGD+I+TGTP G L PGD +E IG Sbjct: 248 SFSTLLPGDVIMTGTPNASG-------HLDPGDETIVHVEGIG 283 >UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=5; Bacteria|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Novosphingobium aromaticivorans (strain DSM 12444) Length = 296 Score = 111 bits (266), Expect = 3e-23 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 12/208 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++CV LNY +E P P F K P T + + ++ + K + E E+ +V Sbjct: 47 KIICVHLNYHSRVQEFITKLPPAPTYFQK-PLTALNTHKGAIVRPERCKWLNYEGEIAIV 105 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 IGK + + A DY+LGY++A D G D+ ++ +L K DT CPIGP +VT Sbjct: 106 IGKTCRNISPAEAGDYILGYSVANDYGLHDF-RDTDAGSMLRVKGSDTLCPIGPGLVTGW 164 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 + + ++ +NGV KQ+ NT+ + ++A ++ +TL PGD++L+GTP Sbjct: 165 DFRDKM---IRTYVNGVLKQEDNTSNMEWDMHYLVADIARTITLEPGDVLLSGTPAN--- 218 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282 P +Q GDV+ E++ +G + Sbjct: 219 -SRP---VQIGDVVEVEVDGLGRLSNTI 242 >UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=11; Bradyrhizobiaceae|Rep: Fumarylacetoacetate (FAA) hydrolase - Rhodopseudomonas palustris Length = 233 Score = 110 bits (265), Expect = 3e-23 Identities = 68/210 (32%), Positives = 101/210 (48%), Gaps = 11/210 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 ++ CVG NY +H E + PF F K V TI ++K + E+EL V Sbjct: 29 RIWCVGRNYLEHVREMGNDERQPPFFFAKHADMVTPDGATIPYP-PLTKDLHHEVELVVA 87 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTFCPIGPWIVT 192 + + A D+V GY + D+ D + KK +GK+ D P G + Sbjct: 88 LKSGRLNIPVERALDHVWGYAVGIDLTRRDLQIASRKKEQPWEIGKSFDASAPCGA-LRP 146 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252 + EIG+P + S+NG ++Q + ++ I +P+IIA+LS + L GDII+TGTP GV Sbjct: 147 ASEIGHPATGKIWLSVNGTERQTGDLSEMIWNVPEIIAKLSAQVELAAGDIIMTGTPAGV 206 Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRV 282 L PGD I I+ IGT + Sbjct: 207 AA-------LSPGDAIACGIDGIGTLNVTI 229 >UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase - Sphingomonas wittichii RW1 Length = 325 Score = 110 bits (264), Expect = 5e-23 Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 8/199 (4%) Query: 88 EEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHA 147 ++ K PP P++F K + G D I L + + + E EL VVIG + + A Sbjct: 121 DQGKQLPPLRPYMFGKI-NVPTGAFDDIILPPGMER-IDWEAELMVVIGTPGLAIRPAEA 178 Query: 148 FDYVLGYTIAQDIGATD--WEKNKKI--SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLN 203 ++ GY D+ D W +++ S L GK+ D+F P+GP + + + +L Sbjct: 179 HRHIAGYMTGNDVSCRDRTWREDRPTIRSDWLGGKSYDSFAPLGPLLTPRQFVPDHADLA 238 Query: 204 VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQ 263 ++ +NG KQ N+ I + I S++MTLLPGD+I TGTP G G R EFL+ Sbjct: 239 IRLWVNGELKQDGNSRDMTFGIEEQIEYASSMMTLLPGDVIATGTPAGTGQERG--EFLK 296 Query: 264 PGDVITSEIENIGTFETRV 282 GD++ +E+E+ G RV Sbjct: 297 EGDIVETEVESCGRQRNRV 315 >UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Comamonas testosteroni KF-1 Length = 289 Score = 110 bits (264), Expect = 5e-23 Identities = 65/189 (34%), Positives = 99/189 (52%), Gaps = 9/189 (4%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVG--PNDTIKLKMD-VSKAV 125 P+H ++ CVG NY+DH +E T E PF F K V T ++ +++ + Sbjct: 81 PIH---RIYCVGRNYEDHAKEMGFTGREPPFFFMKPADATVALEAGSTGQVAYPTLTQNL 137 Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTF 183 EIEL V IGK + ++ A Y+ GY + D+ D E K+ +GKA + Sbjct: 138 HHEIELVVAIGKAGKNIKAADALQYIYGYAVGLDMTRRDLQNEMKKQGRPWCIGKAFEQS 197 Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243 PIGP I +D+ G+ N + +NG +Q+S+ ++ I I + I LS+ L PGD+ Sbjct: 198 APIGP-ITPADQAGDIANAEISLQVNGDYRQRSHIHKLIWNIAETIEHLSSAWELQPGDL 256 Query: 244 ILTGTPGGV 252 I+TGTP GV Sbjct: 257 IMTGTPEGV 265 >UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2; Eurotiomycetidae|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 327 Score = 110 bits (264), Expect = 5e-23 Identities = 68/217 (31%), Positives = 112/217 (51%), Gaps = 7/217 (3%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-C 127 PV G + ++CVGLNY++H E L P P ++ K P + P+ I + K+ Sbjct: 113 PVTGIN-IICVGLNYRNHANEASLPIPTCPPMWYKAPPALADPDSEIPVPPQAQKSFPDF 171 Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187 E ELT+V+ + +S A ++LGYTI D+ A +++ Q K D F P+G Sbjct: 172 EGELTIVLRNTIKSISASEATSHILGYTIGNDLTARFFQRACG-GQYTHAKGFDNFAPLG 230 Query: 188 PWIVTSDEIGNPQNLN--VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 P +V + +P + + + +NG Q S + FI + ++++ LS T+ G I+ Sbjct: 231 PRLV-HPSVFSPSDASRRITTRVNGRVVQDSPFD-FIFPVDELVSFLSEGTTIPAGTAIM 288 Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TGTP GVG +++P LQ GD + E++ IG + Sbjct: 289 TGTPAGVGWFQDPKCPLQHGDAVEVEVQPIGVLRNTI 325 >UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=123; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 252 Score = 109 bits (261), Expect = 1e-22 Identities = 69/208 (33%), Positives = 103/208 (49%), Gaps = 12/208 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133 +V CVG NY DH E P E PF F K +V + T+ ++ + EIEL V Sbjct: 47 RVFCVGRNYADHAREMGADPDREPPFFFTKPADAIVPASGTVAYP-PLTNDLHHEIELVV 105 Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLL-LGKAMDTFCPIGPWIV 191 IGK +D + A +V GY + D+ D + KK+S+ K D P+ + Sbjct: 106 AIGKDGRAIDPADALSHVWGYGVGIDLTRRDLQAEAKKLSRPWDWAKGFDASGPVTA-LR 164 Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251 + G+P + ++NG +Q+ + I +PD+IA +S + L GD+I TGTP G Sbjct: 165 AASATGHPATGRIWLAVNGDTRQQGDLADMIWAVPDVIAYVSRSVELKAGDLIFTGTPAG 224 Query: 252 VGVYRNPPEFLQPGDVITSEIENIGTFE 279 VG LQPGD +T ++ + TFE Sbjct: 225 VGA-------LQPGDRVTGGVDGVATFE 245 >UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Mycobacterium sp. JLS|Rep: Fumarylacetoacetate (FAA) hydrolase - Mycobacterium sp. (strain JLS) Length = 265 Score = 109 bits (261), Expect = 1e-22 Identities = 72/228 (31%), Positives = 110/228 (48%), Gaps = 8/228 (3%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPNDTIKLKM 119 L + L P+ V+ VG+NY H E+ +T P+ F K + ++G D + + Sbjct: 39 LDDVRLLPPITPTSTVVGVGMNYWSHLEKLGVTERPKSTLGFLKPRAAIIGHGDVLANPV 98 Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG-K 178 +++ + E+EL VV+ + S + VLGYT+ D+ A D L K Sbjct: 99 -ITEQLDFEVELVVVLAQSVSH-PGGRPTEAVLGYTVGNDVSARDAAVPMSGGLDLFSIK 156 Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCS--INGVQKQKSNTNQFIHKIPDIIARLSNVM 236 A+ P+GPWI T DE G ++V S +NG Q+Q T + I I + + + M Sbjct: 157 ALGGTTPVGPWITTKDEFGGSGQIDVGISLRVNGEQRQHDRTGKMIFSIDECLDYVVARM 216 Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 L GDI+ TGT GVG +LQ GDV+ +E+E +G V E Sbjct: 217 PLAAGDIVFTGTTHGVGF--EDGRYLQAGDVVEAEVEGVGVLRNIVGE 262 >UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella pertussis|Rep: Putative hydrolase - Bordetella pertussis Length = 316 Score = 108 bits (259), Expect = 2e-22 Identities = 62/192 (32%), Positives = 102/192 (53%), Gaps = 7/192 (3%) Query: 96 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASK-VDSSHAFDYVLGY 154 ++P F K S V+ P+D+ + A E+E+ V+G A ++V GY Sbjct: 126 DMPAGFIKIAS-VMTPHDSAVARPCGVLAFDYEVEVAAVLGGPVPLGTPPERALEHVFGY 184 Query: 155 TIAQDIGATDWEKNKKISQLL-LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213 T+ D+ A +W + + +Q++ +GK P+GPWIVT+DE+ +P L + S+NG + Sbjct: 185 TLFNDLSAREWARAEMKNQMIAMGKNFPGAGPLGPWIVTADEVPDPAQLELSLSVNGEPR 244 Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP---PEFLQPGDVITS 270 Q + + I +IA S + L G++I +GTP G + R P P FL+PGD++ + Sbjct: 245 QHGSCKEMIFTFAQLIAHWSRI-GLGAGELIASGTPEGGAISRKPDPAPFFLKPGDIVEA 303 Query: 271 EIENIGTFETRV 282 IGT TR+ Sbjct: 304 HCPQIGTLRTRI 315 >UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=3; Burkholderiales|Rep: 2-Keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier337)) Length = 301 Score = 108 bits (259), Expect = 2e-22 Identities = 60/163 (36%), Positives = 92/163 (56%), Gaps = 9/163 (5%) Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL------LG-KAM 180 E EL VVIGK + A D V GYTIA D+ A D + +++ +G K Sbjct: 141 EAELAVVIGKACRNISPGDALDCVAGYTIANDLSARDNLRREQVDASSPFRFDWIGHKCF 200 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 + CP+GP++ + + +P+ L++K +N KQ SNT+ ++ + + IA LS +TL P Sbjct: 201 EGSCPLGPYLTPAAFVASPEALDIKLWVNDELKQNSNTSNHLYTVAEQIAYLSERLTLYP 260 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 GD++LTGTP GVG+ FL+ GD I I+ +G ET ++ Sbjct: 261 GDVLLTGTPAGVGM--ESGVFLKRGDSIRVWIDGLGELETSLQ 301 >UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG10641.1 - Gibberella zeae PH-1 Length = 230 Score = 107 bits (258), Expect = 2e-22 Identities = 62/151 (41%), Positives = 81/151 (53%), Gaps = 3/151 (1%) Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187 E EL VVIG+ A V A +YVLGYT A DI + + + SQ K D CP+G Sbjct: 73 EAELAVVIGRAAKNVTKEEAMEYVLGYTAANDISSRTSQFGQ--SQWCFSKGFDGSCPLG 130 Query: 188 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247 P +V+ D + +P N++ Q + I IP +I+ LS TLLPG +ILTG Sbjct: 131 PALVSKDLVPDPSMFNIRGLKKDQVLQDCGADDLIFDIPTLISFLSQGTTLLPGTVILTG 190 Query: 248 TPGGVGVYRNPPEFLQPGDVITSEI-ENIGT 277 TP GVGV R P + GD + EI +IGT Sbjct: 191 TPAGVGVGRQPKVTISDGDEFSVEILPHIGT 221 >UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4; Alphaproteobacteria|Rep: Possible isomerase/decarboxylase - Rhodopseudomonas palustris Length = 329 Score = 107 bits (257), Expect = 3e-22 Identities = 65/187 (34%), Positives = 102/187 (54%), Gaps = 6/187 (3%) Query: 99 FIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQ 158 +I N+F +V G N +K S + E+E ++ +K + + ++ A +++ GYTI Sbjct: 143 YITNRF--SVRGTNTVVKWPR-YSAVMDYELEFGIITKRKGANISAAQAKNHIFGYTIFN 199 Query: 159 DIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKS 216 D A D ++ + +L GK+ D IGPWIVT DEIG+P LN++ +NG + + Sbjct: 200 DFSARDAQRIEMEGRLGPAKGKSFDGGNVIGPWIVTPDEIGDPYRLNMEARVNGEVRSRG 259 Query: 217 NTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276 T + +IIA +S TL+PG+ I +GT G G FL+ GDVI E+E IG Sbjct: 260 VTEGMLFSFEEIIAHVSRDETLMPGEFIGSGTVGN-GCGLELGWFLEHGDVIELEVEKIG 318 Query: 277 TFETRVE 283 + +VE Sbjct: 319 IPKNKVE 325 >UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep: ENSANGP00000019097 - Anopheles gambiae str. PEST Length = 232 Score = 106 bits (255), Expect = 6e-22 Identities = 64/188 (34%), Positives = 97/188 (51%), Gaps = 6/188 (3%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT---IKLKMDVSKAVVCEIEL 131 K++ G+NYK+ P+ P IF K S G T I++ + E EL Sbjct: 24 KIIGAGVNYKEILRLTNSPKPDAPVIFFKPISGSTGSTGTPPTIRIPRVFGGVINFEAEL 83 Query: 132 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPW 189 V+IG++ + V + A YV GY +A D+ D+ + + L LGK DT P+ Sbjct: 84 GVIIGRRCANVPTDQAMAYVGGYCLALDMTGMDFILDARPKGLPWCLGKGFDTSTPVSAL 143 Query: 190 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 249 + +D + NP ++ V C +NGV+KQ +T I I ++IA +S MTL D++LTGTP Sbjct: 144 VQRAD-LPNPDDVRVWCEVNGVRKQDDSTRNLIFPIAELIAYVSRFMTLEENDLLLTGTP 202 Query: 250 GGVGVYRN 257 G G R+ Sbjct: 203 AGAGPVRH 210 >UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Thermosinus carboxydivorans Nor1|Rep: Fumarylacetoacetate (FAA) hydrolase - Thermosinus carboxydivorans Nor1 Length = 295 Score = 106 bits (254), Expect = 7e-22 Identities = 67/189 (35%), Positives = 97/189 (51%), Gaps = 4/189 (2%) Query: 68 APVHGN-DKVLCVGLNYKDHCEEQKLTPPEL-PFIFNKFPSTVVGPNDTIKLKMDVSKAV 125 AP++ + K+ +GLNY DH + P L P F KF +T++GP + IK+ + S+ Sbjct: 80 APLYRHPSKIWGIGLNYVDHAGDLAEKAPTLAPASFAKFDTTIIGPGEEIKIPLQ-SEKT 138 Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185 E EL ++ GKK V+ + V G+T D+ A D + L K DTF Sbjct: 139 TGESELAIIFGKKCKDVEEKDWLNVVAGFTTIIDMTAEDILRINP-RYLTRAKNFDTFLS 197 Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 GP +VT DEI + LNV ING ++ + +++ S V T+LPGDIIL Sbjct: 198 FGPVLVTPDEIEDVNKLNVATVINGRIHARNVVSNMTFPPAYLVSFHSKVATMLPGDIIL 257 Query: 246 TGTPGGVGV 254 TGTP V + Sbjct: 258 TGTPRAVQI 266 >UniRef50_A1HJ09 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=2; Ralstonia pickettii|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Ralstonia pickettii 12J Length = 250 Score = 106 bits (254), Expect = 7e-22 Identities = 63/187 (33%), Positives = 96/187 (51%), Gaps = 11/187 (5%) Query: 94 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 153 PP+ P ++ K +T +G + L DV V L V I A++V + HA D++ G Sbjct: 64 PPKAPILYLKPANTRIGHGHEVALPADVD-GVWAGACLGVAISCTATRVPAQHAADFIAG 122 Query: 154 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213 YTI D+ + + K D FCP+GPW+V D++ N L++ ING K Sbjct: 123 YTIVNDLTVPHASYYRPA---IRHKCRDGFCPMGPWMVDRDDVPNADALDITVRINGEVK 179 Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273 Q++NT+ + I ++A ++ MTL GD++L G P NPP + GD I +I Sbjct: 180 QRANTSTLVRPIAQLLADVTAFMTLESGDVLLVGMP------ENPP-LARAGDRIDIDIA 232 Query: 274 NIGTFET 280 +IGT T Sbjct: 233 HIGTLTT 239 >UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep: MelH protein - Melittangium lichenicola Length = 329 Score = 105 bits (253), Expect = 1e-21 Identities = 78/262 (29%), Positives = 122/262 (46%), Gaps = 16/262 (6%) Query: 8 YKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXXLS--GIT 65 +K IR G + D +V I P +TL L L+ + Sbjct: 8 FKTGSEIRWGVVQRDRLVVI----PGQYATLAGFLGEGAAHARRLAAAPEGETLAVRDVE 63 Query: 66 LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPF--IFNKFPSTVVGPNDTIKLKMDVSK 123 L +PV V+C G NY+ H E P F F K S++ + I +K + + Sbjct: 64 LLSPVTAPCNVVCQGQNYRSHMLEVGQDPEAKNFNQFFRKASSSLTSGHGDI-VKPERVR 122 Query: 124 AVVCEIELTVVIGKKAS---KVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180 + EIEL +VIG+ S +V+ ++V G I D+ A D + + Q K+ Sbjct: 123 MLDYEIELGLVIGRPLSGPCRVERERLHEFVAGLVICNDVSARDIQLAE--GQWYKSKSF 180 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKC--SINGVQKQKSNTNQFIHKIPDIIARLSNVMTL 238 TFCP GP++ D N + +N+K S+N +Q SNT++ ++ + ++ LS VM L Sbjct: 181 RTFCPAGPYLYLLDAEDNARVMNLKLHLSVNDQTRQDSNTSEMVYPPEETLSELSEVMDL 240 Query: 239 LPGDIILTGTPGGVGVYRNPPE 260 PGD+++TGTP GV N P+ Sbjct: 241 FPGDLVMTGTPRGVAAGHNAPK 262 >UniRef50_Q3INL8 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 2; probable 5- oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 2; n=1; Natronomonas pharaonis DSM 2160|Rep: Probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 2; probable 5- oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 2 - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 319 Score = 104 bits (249), Expect = 3e-21 Identities = 58/188 (30%), Positives = 99/188 (52%), Gaps = 5/188 (2%) Query: 96 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 155 E+P + +VV P +T++ S + E+EL VIGK+ + + A +Y+ GYT Sbjct: 135 EMPVYYKSTADSVVAPGETVEWPA-YSSLMDYELELAAVIGKEGRDIPAEAADEYIAGYT 193 Query: 156 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQK 215 I D A D + + ++L K D GP++VT+D+ +P+ ++ ++NG + Sbjct: 194 IFNDFSARDIQGEEMQARLGPAKGKDFANAFGPYLVTADDF-DPETAEMRATVNGEVWSE 252 Query: 216 SNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG-GVGVYRNPPEFLQPGDVITSEIEN 274 + H DI+A +S TL PGD++ +GT G G G+ +FL+ GD ++ ++ Sbjct: 253 GTPGEMYHTFADIVAHVSQSETLYPGDVLGSGTVGEGCGLELG--QFLESGDTVSLFVDG 310 Query: 275 IGTFETRV 282 IGT E V Sbjct: 311 IGTLENTV 318 >UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 295 Score = 103 bits (248), Expect = 4e-21 Identities = 65/211 (30%), Positives = 104/211 (49%), Gaps = 10/211 (4%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++ V L Y+ EE P P F K P+ + G ++ ++ + E EL V+ Sbjct: 57 KIIAVHLTYRSRVEEYGARVPPEPSYFLKPPTALNGHRGVVRWPAG-TRFLNYEGELAVI 115 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194 +G++ V A V GYT A D+G D+ + S L + K D F P+GP +V + Sbjct: 116 VGRRMKGVGMEEALSCVAGYTCANDVGLHDFRHADRGSMLRV-KGQDGFLPLGPEVVPAS 174 Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254 +P++ ++ +NG Q+ + + +A L ++TL PGD++LTGTP Sbjct: 175 RF-DPEDFALRTYLNGEVVQEGGAEDLLFGVAYQLADLCRLITLEPGDVVLTGTPAN--- 230 Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRVEEF 285 P ++PGDV+ EIE IG VEE+ Sbjct: 231 -SRP---MRPGDVVEVEIEGIGRLSNTVEEW 257 >UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Arthrobacter|Rep: Fumarylacetoacetate (FAA) hydrolase - Arthrobacter sp. (strain FB24) Length = 277 Score = 103 bits (248), Expect = 4e-21 Identities = 65/187 (34%), Positives = 101/187 (54%), Gaps = 13/187 (6%) Query: 98 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 157 P F+K ++VVGP D I+L V V E ELT+VIG+KA + +A VLG+TI Sbjct: 102 PQAFHKAATSVVGPGDAIELAPGVGH-VDPEAELTIVIGRKARGLTLENARGAVLGFTIG 160 Query: 158 QDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSN 217 D+ A + +K+ ++ + K+ DTF P GPWIVT + L++ NG + + ++ Sbjct: 161 NDVTARELQKSDEL--WISAKSQDTFTPAGPWIVTGLDTA---ALSIGIVHNGSELRAAS 215 Query: 218 TNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGT 277 + K+ +I+ L++ MTL PGD++LTG P L PGD +T ++ IG Sbjct: 216 SADLGWKVDEILVYLTSFMTLHPGDLVLTGFPA-------ESARLHPGDTVTCRVQGIGE 268 Query: 278 FETRVEE 284 V + Sbjct: 269 LTNPVSD 275 >UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Aeropyrum pernix|Rep: Fumarylacetoacetate hydrolase family protein - Aeropyrum pernix Length = 286 Score = 103 bits (248), Expect = 4e-21 Identities = 64/204 (31%), Positives = 106/204 (51%), Gaps = 6/204 (2%) Query: 79 VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 138 VG +Y +H E ++ ++ F F+K +++ G + + + VS+ E E+ ++IGK+ Sbjct: 82 VGRSYAEHAREMGMSK-QIAF-FSKPVTSLTGHLNPVVVP-PVSEKPDYEGEIVIIIGKR 138 Query: 139 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 198 ++ A + GYT DI TD +S + K +DT+ P+GP D + Sbjct: 139 IKNASTAEAGKAIAGYTAGADI--TDRLLQDMMSWSM-AKGLDTYGPVGPVATIIDSPDD 195 Query: 199 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 258 L V +NG + Q+ T I IPD+++RLS + TL PGDI+ TGTP GVG R P Sbjct: 196 LDGLCVHTWLNGEKVQRGCTGDMIVSIPDMVSRLSALATLRPGDIVFTGTPPGVGHARKP 255 Query: 259 PEFLQPGDVITSEIENIGTFETRV 282 P +L+ GD + + + ++ Sbjct: 256 PRYLRHGDELEVRVSGLPPLRNQI 279 >UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium japonicum|Rep: Blr7583 protein - Bradyrhizobium japonicum Length = 261 Score = 103 bits (246), Expect = 7e-21 Identities = 66/210 (31%), Positives = 98/210 (46%), Gaps = 18/210 (8%) Query: 78 CVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 131 CVGLNY H +E + P+ P I + + ++ ++ + + + + E EL Sbjct: 58 CVGLNYLKHLKEAADKRGEVPAVPDRPEIGYRAQNALIAHDEEVVIPSFATDKIHYEGEL 117 Query: 132 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 191 VVIGKK + +A D V GYTI D+ W+K + L K DTF P+GPWI Sbjct: 118 VVVIGKKVKHLTKQNAMDCVFGYTIGNDVSERSWQKADR--SLWRSKNADTFKPMGPWIE 175 Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251 T N + +NG + + TN I + + L+ TL PGD+I GT G Sbjct: 176 TE---ANLARMETVVRVNGKETNRFYTNDMIFGVVPFLVELTKYFTLWPGDVIWMGTDGA 232 Query: 252 VGVYRNPPEFLQPGDVITSEIENIGTFETR 281 P+ ++ GDV+ +I IGT R Sbjct: 233 ------SPD-IKHGDVVEIDITGIGTLRNR 255 >UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=1; Schizosaccharomyces pombe|Rep: Uncharacterized hydrolase C21C3.09c - Schizosaccharomyces pombe (Fission yeast) Length = 221 Score = 103 bits (246), Expect = 7e-21 Identities = 67/202 (33%), Positives = 107/202 (52%), Gaps = 12/202 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKLKMDVSKAVVCEIELTV 133 KV+C+G NY H E P PF F K S +V P + + + DVS E+ L + Sbjct: 7 KVVCIGRNYAAHIRELNNPFPTKPFFFLKPTSAIVEPGHGNLIIPPDVSAHYEVELGLIM 66 Query: 134 VIGKKASKVDSSHAF-DYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWI 190 A + SS+++ D + Y + D+ A + + K L K DTF P+GP I Sbjct: 67 KDRLPARRPVSSNSWLDSIGAYFVGIDMTARNIQNEAKKKGLPWSFAKGYDTFLPVGP-I 125 Query: 191 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 250 + I +P N+ ++ S+NG QK +T+ ++KIP I + ++ M+L PGD++LTGTP Sbjct: 126 IPKHLIPDPHNVILELSLNGKVVQKDSTSLMLNKIPKIFSSITEAMSLNPGDLVLTGTPK 185 Query: 251 GVGVYRNPPEFLQPGDVITSEI 272 GVG + PGD++++ + Sbjct: 186 GVGP-------VVPGDILSARL 200 >UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP02096p - Drosophila melanogaster (Fruit fly) Length = 236 Score = 102 bits (245), Expect = 9e-21 Identities = 71/211 (33%), Positives = 105/211 (49%), Gaps = 11/211 (5%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++ V LNY D + + P+ P +F K S+ + I L +K V E+EL VV Sbjct: 33 KIVGVALNYMDVVLARNVPVPKEPLVFLKPTSSYLQEGQPIVLPKVFTK-VAYEVELGVV 91 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 192 IGK V + A YV GY +A D+ A + + LGK DT P+ +I Sbjct: 92 IGKPCKNVSKADAMSYVAGYCLALDLTAQCNLGPARAAGHPWTLGKGFDTSTPVSQFIPI 151 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252 +++ +P NL + ++NG KQ T I K+PDII+ +S MTL D+ILTGTP G Sbjct: 152 -EKVTDPHNLPLWLTVNGDLKQNGCTADLIFKVPDIISYVSKYMTLEANDLILTGTPNGA 210 Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 ++ GDVI + ++ +VE Sbjct: 211 DAFK-------AGDVIQCGMADLAKLTFQVE 234 >UniRef50_UPI00006CDD7C Cluster: fumarylacetoacetate hydrolase family protein; n=1; Tetrahymena thermophila SB210|Rep: fumarylacetoacetate hydrolase family protein - Tetrahymena thermophila SB210 Length = 218 Score = 101 bits (243), Expect = 2e-20 Identities = 68/181 (37%), Positives = 92/181 (50%), Gaps = 12/181 (6%) Query: 73 NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 132 N K+L + NY QK P + P IF K S+++ + + L + EIEL Sbjct: 13 NPKILALAQNYIP--PGQKDVPAQ-PLIFTKPHSSILYKGENLILNS--KNQINYEIELG 67 Query: 133 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ----LLLGKAMDTFCPIGP 188 V+IGK + AFDY+ GY + D+ TDW+ K + +GK D F PI Sbjct: 68 VMIGKSGKNIAKQQAFDYIGGYFLCLDM--TDWDMQKANRKNGFPWDIGKGQDGFLPISD 125 Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248 +I D I +P N+N+K IN + NT KI DII +S MTL PGD+ILTGT Sbjct: 126 FIEKKD-IKDPHNINLKLQINQKSEVDDNTKNMYFKIDDIIQYVSQYMTLNPGDLILTGT 184 Query: 249 P 249 P Sbjct: 185 P 185 >UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family protein; n=25; Enterobacteriaceae|Rep: Fumarylacetoacetate hydrolase family protein - Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) Length = 218 Score = 101 bits (243), Expect = 2e-20 Identities = 73/222 (32%), Positives = 107/222 (48%), Gaps = 15/222 (6%) Query: 63 GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122 G L PV+ KV+CVG NY +H +E P P +F K + + + + ++ Sbjct: 9 GALLDFPVN---KVVCVGSNYSEHIKEMGSATPSEPVLFIKPETALCDLRQPVAIPKNLG 65 Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLL-LGKAM 180 +V E+EL V+IG + + + GY +A D+ D + KK Q KA Sbjct: 66 -SVHHEVELAVLIGTPLKQANEERVARAIAGYGVALDLTLRDLQSEFKKAGQPWEKAKAF 124 Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240 D CPI +I + E G+PQ + +N +Q+ NT I I +IA +S TL Sbjct: 125 DGSCPISGFIPVA-EFGDPQQTELGVKVNDEVRQQGNTRDMITSILPLIAYMSRFFTLRA 183 Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 GDIILTGTP GVG + GD++T + N T TR+ Sbjct: 184 GDIILTGTPKGVGP-------ILSGDMLTITV-NDRTLSTRI 217 >UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=8; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Silicibacter sp. (strain TM1040) Length = 256 Score = 101 bits (242), Expect = 2e-20 Identities = 65/182 (35%), Positives = 93/182 (51%), Gaps = 6/182 (3%) Query: 75 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133 +V C+G NY H E P E PF F K P ++ M S+ V E EL V Sbjct: 55 RVYCIGRNYAAHAVEMGHDPDREPPFFFQKTPDSLDASGRFPYPVM--SEDVHHEAELLV 112 Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK-NKKISQLL-LGKAMDTFCPIGPWIV 191 +GK + A D+V GY +A D+ D + KK + +GK+ + P+ P + Sbjct: 113 ALGKGGENISEDAALDHVWGYGLALDMTRRDLQGIAKKAGRPWEIGKSFEHAAPVAP-LT 171 Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251 + IG+P + ++NG +Q+ + NQ I KIP++IA LS L GD+ILTGTP G Sbjct: 172 PATTIGHPDAGVMTLTVNGTPRQQGDLNQMIWKIPEMIAHLSQYYRLAAGDVILTGTPAG 231 Query: 252 VG 253 VG Sbjct: 232 VG 233 >UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation; 2-hydroxyhepta-2,4-diene-1,7- dioate isomerase; n=8; Pseudomonas|Rep: 4-hydroxyphenylacetate degradation; 2-hydroxyhepta-2,4-diene-1,7- dioate isomerase - Pseudomonas entomophila (strain L48) Length = 224 Score = 100 bits (240), Expect = 4e-20 Identities = 59/184 (32%), Positives = 95/184 (51%), Gaps = 13/184 (7%) Query: 94 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 153 PP P +F K P+T + V K + L VV+G+ AS+V + +A ++V G Sbjct: 39 PPVKPVLFIKTPNTRNSHGQAVTYPAAV-KRLQPGPALGVVMGRDASRVSAENALEHVAG 97 Query: 154 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213 YTI + + + + K D FCP+GP +V + ++ NP L ++ +NG + Sbjct: 98 YTIVNEFSLPE---DSYYRPAVKAKCRDGFCPLGPQLVPAAQVANPDALGIRLWVNGELR 154 Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP-GGVGVYRNPPEFLQPGDVITSEI 272 Q +NT + + +IA +S MTL GD+++TGTP G + V PGD +T EI Sbjct: 155 QHNNTANCVRSVAQLIAEISEFMTLHAGDVLITGTPEGRIDVL--------PGDRVTVEI 206 Query: 273 ENIG 276 + +G Sbjct: 207 DGLG 210 >UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 313 Score = 100 bits (240), Expect = 4e-20 Identities = 59/177 (33%), Positives = 91/177 (51%), Gaps = 5/177 (2%) Query: 95 PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGY 154 P +P +F K ST+ GP I + V++ E+EL VV+G+ V A D +LGY Sbjct: 108 PVIPILFYKPISTLSGPGRDIVIPPCVAEQADYEVELVVVLGRDIKDVSPVEAMDAILGY 167 Query: 155 TIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE---IGNPQNLNVKCSINGV 211 T++ D+ A + + Q LGK+ D + PIGP +V++ I N N+++ +N Sbjct: 168 TLSNDVSAR--TRMFAVPQWGLGKSFDGWLPIGPCLVSASNPRGITNRDNIHLTTKLNNR 225 Query: 212 QKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVI 268 Q NT+ + K + +A LS TL G +++ GTP G G R P L GD + Sbjct: 226 IMQDGNTSDMLWKTAETLAELSKGTTLEAGSLLIMGTPPGEGFKRQPKVCLNHGDTL 282 >UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Fumarylacetoacetate (FAA) hydrolase - Halorubrum lacusprofundi ATCC 49239 Length = 273 Score = 100 bits (239), Expect = 5e-20 Identities = 68/221 (30%), Positives = 111/221 (50%), Gaps = 12/221 (5%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV-S 122 I+ AP+ K+ +GLNY +H + P+ P F K S + GP+ I+L + S Sbjct: 61 ISFGAPLESFGKLWGIGLNYAEHAGDLDEQRPDEPASFMKPSSVLTGPSGPIRLPPESQS 120 Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATD-WEKNKKISQLLLGKAMD 181 + V E EL VV+G+ V+ + D V G+ D+ A D ++N + L K+ D Sbjct: 121 ERVTAEAELAVVMGRTCRNVEEAAFEDVVAGFLPVIDMTAEDVLQRNPRF--LTRSKSYD 178 Query: 182 TFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241 TF G + +E + L+V+ +NG + ++ + +I++ S+VMTL PG Sbjct: 179 TFLVPGAALAVPEEPLDLDALSVQTEVNGEIEAENEIRNMLFPPSEIVSFHSDVMTLEPG 238 Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 D+ TGTPG ++PGD + + +E+IGT E V Sbjct: 239 DLFSTGTPGAA--------HIEPGDEVRAVVESIGTVEAPV 271 >UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family protein; n=13; Bacillus|Rep: Fumarylacetoacetate hydrolase family protein - Bacillus anthracis Length = 318 Score = 99.5 bits (237), Expect = 8e-20 Identities = 81/303 (26%), Positives = 135/303 (44%), Gaps = 22/303 (7%) Query: 1 MKLLQFSYKNSDGIRAGFLDGDNVVDIN-KEDPKLPSTLIELLKTNXXXXXXXXXXXX-- 57 MK + F + + +RAG+L+GD V+D+N D KLPS++ L+ Sbjct: 1 MKFVTFRLPSKE-MRAGWLEGDKVIDMNLASDGKLPSSMFAFLEKADEYVEVLRNIKNPE 59 Query: 58 --XXXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQK------LTPP--ELPFIFNKFPST 107 L + L A + N + ++ H + + + P ++P + Sbjct: 60 KGIYSLEEVQLAAAIP-NPSSIRDFYAFEQHVKTARGRRGLDVVPEWYDIPVFYFTNHRA 118 Query: 108 VVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK 167 V+GPND + + S+ + E+E+ VIGK+ + A +Y+ GY I D A D + Sbjct: 119 VIGPNDVV-IGPKKSEKIDYELEIACVIGKEGRNISREQAEEYIFGYCIMNDWSARDLQA 177 Query: 168 NKKISQLLLGKAMDTFCPIGPWIVTSDEI-----GNPQNLNVKCSINGVQKQKSNTNQFI 222 + L K D +G +VT +E+ G+ L + +NG K N Sbjct: 178 TEMKVGLGPAKGKDFATSLGAHLVTKEELDVYRNGDRYELEMTAHVNGKLLSKGNFQDIY 237 Query: 223 HKIPDIIARLSNVMTLLPGDIILTGTPG-GVGVYRNPPEFLQPGDVITSEIENIGTFETR 281 + ++I R S +TL PGD+I +GT G G + E+LQ GDV+ I +GT Sbjct: 238 YTFAEMIERASEDVTLYPGDVIGSGTVGTGCILELGTEEWLQDGDVVELTITGLGTLRNT 297 Query: 282 VEE 284 V++ Sbjct: 298 VKK 300 >UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 255 Score = 98.3 bits (234), Expect = 2e-19 Identities = 60/197 (30%), Positives = 99/197 (50%), Gaps = 3/197 (1%) Query: 90 QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTVVIGKKASKVDSSHAF 148 QKLT P P ++ K +++ PN+ I + ++++ E EL V ++ V S A Sbjct: 57 QKLTIPSNPPLWTKPAASLAHPNEEIPINDFCARSLPDYEGELVFVTSEECKDVTESQAK 116 Query: 149 DYVLGYTIAQDIGATDWEKNKKIS-QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCS 207 DY+LGYTI D+ ++ +S Q KA D F PI P +++ + + + Sbjct: 117 DYILGYTIGNDLTCRMFQLPGNMSGQFFFAKAFDHFAPIDPVLISPKLFESVKRNGLTLK 176 Query: 208 INGVQKQKSNT-NQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGD 266 +NG +QK++ N I I++ +S T+ G ++TGT GVG +R P FLQ GD Sbjct: 177 VNGEVRQKADLHNDMIFSPERILSHMSQGTTIPAGTAVMTGTCEGVGAFRKPKVFLQQGD 236 Query: 267 VITSEIENIGTFETRVE 283 V+ + GT ++ Sbjct: 237 VVEVSMPLAGTLRNTIK 253 >UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA) hydrolase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 349 Score = 97.9 bits (233), Expect = 3e-19 Identities = 58/183 (31%), Positives = 88/183 (48%), Gaps = 7/183 (3%) Query: 98 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 157 P++F P+ + GP D + L + + E+E VIG+ V A D V GYTIA Sbjct: 145 PYLFLGSPTALCGPYDDVVLPAEGDQHD-WELEFAAVIGRSGRHVPPERALDLVAGYTIA 203 Query: 158 QDIGATDWEKNKKISQL----LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213 DI D + + L K TF P GP+IV + +G+ L + +NG Sbjct: 204 NDITTRDLVYRPDLKAIGTDWLRSKNAPTFLPTGPYIVPKEFVGDTSGLRITLRLNGETM 263 Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273 Q + + I + +++ S+ + L PGD+ILTG+P G G Y FL GDV+ + Sbjct: 264 QDESASDMIFDVARLVSYASSRVLLRPGDLILTGSPAGNGSYWG--RFLGEGDVMEGTVT 321 Query: 274 NIG 276 +G Sbjct: 322 GLG 324 >UniRef50_Q9X4X0 Cluster: DitH; n=8; Proteobacteria|Rep: DitH - Pseudomonas abietaniphila Length = 336 Score = 97.5 bits (232), Expect = 3e-19 Identities = 59/176 (33%), Positives = 94/176 (53%), Gaps = 6/176 (3%) Query: 102 NKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIG 161 N+F V+G +D L SKA+ E+E IGKK + +A D+++G+TI D+ Sbjct: 147 NRF--AVIGADDEF-LWPAFSKALDFELEFGCYIGKKGKDISRDNARDHIVGFTIFNDMS 203 Query: 162 ATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTN 219 A D + + L K DT +GP +VT+DE+G+P +LN+ +NG + + NT Sbjct: 204 ARDAQAAEMPGMLGPAKSKDFDTANIMGPCLVTADELGDPYDLNMVARVNGEEWGRGNTR 263 Query: 220 QFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 275 + D+IA +S TL PG+ + +GT G G +L+PGD + E++ I Sbjct: 264 DMRWRFEDVIAHISRSETLYPGEFLGSGTVGN-GCGLEQLRYLKPGDRVELEVDGI 318 >UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep: PlaH - Streptomyces sp. Tu6071 Length = 294 Score = 97.5 bits (232), Expect = 3e-19 Identities = 75/227 (33%), Positives = 106/227 (46%), Gaps = 17/227 (7%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPF---IFNKFPSTVVGPNDTIKL 117 LS +TL P K+ CV LNY P P + K PST+VG + Sbjct: 48 LSEVTLLPPAEPT-KIACVALNYAPQGSPTGPGRPANPAACSVVLKPPSTLVGHGAVVGH 106 Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLL 175 + + + E EL VVIG V + A + V GYT A D+ A ++ S + Sbjct: 107 PGEPWE-LRHEAELAVVIGTACKGVPAERAAEVVAGYTCADDLTAYVRRAPEEPSGHPPV 165 Query: 176 LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNV 235 K DTF P+GPW+ T + P ++ + C +NG +Q T + + +I+A +S Sbjct: 166 WAKHFDTFTPLGPWLTTDLD---PADVPITCRVNGEVRQDGGTRGLLTPVHEIVAVVSRH 222 Query: 236 MTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 M+LLPGD+ILTGTP G G L GD + + IGT V Sbjct: 223 MSLLPGDVILTGTPTGSGP-------LSVGDRVEVSLAGIGTLSHTV 262 >UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase - Jannaschia sp. (strain CCS1) Length = 305 Score = 96.7 bits (230), Expect = 6e-19 Identities = 59/191 (30%), Positives = 95/191 (49%), Gaps = 4/191 (2%) Query: 96 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 155 E P + + +G T++ S + E+EL ++IGK+ + + A +++ GYT Sbjct: 115 EQPIYYKGNRMSFIGHGQTVRWPA-YSDYLDLELELAIIIGKEGADIPRETAHEHIWGYT 173 Query: 156 IAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213 I D+ A D + + QL GK DT +GPWIVT+DE+ +P LN+ S+NG + Sbjct: 174 ILNDVSARDAQMREMAGQLGPAKGKDFDTGNILGPWIVTADEVSHPAVLNMDVSVNGERW 233 Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273 + IIA +S L PG++I +GT G G + L GD++ IE Sbjct: 234 GGGTSADMQFDFAQIIAHISASERLFPGEVIGSGTV-GTGCGLEIGKRLSDGDMMDLTIE 292 Query: 274 NIGTFETRVEE 284 IGT +++ Sbjct: 293 KIGTLTNTIKK 303 >UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|Rep: Bll3146 protein - Bradyrhizobium japonicum Length = 262 Score = 94.7 bits (225), Expect = 2e-18 Identities = 63/201 (31%), Positives = 95/201 (47%), Gaps = 9/201 (4%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELP--FIFNKFPSTVVGPNDTIKLK 118 LS + L AP K++ + N+ H KL PE P K +++ P I+ Sbjct: 48 LSEVELLAPC-APSKIVALWNNF--HALAAKLNQPEPPEPLYLLKATTSIAAPGAVIRRP 104 Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATD-WEKNKKISQLLLG 177 E EL +VIG+ ++V A ++ GYT DI A D + Q Sbjct: 105 SYYDGKTTYEGELGIVIGRTCARVSPGEADSFIFGYTCVNDITANDILTSDPTFPQWARA 164 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 K +D + P GP I T + P L V+ +NG ++Q + I ++++R+S+ MT Sbjct: 165 KGIDDYGPFGPVIATGLD---PAKLVVRTILNGAERQNYPISDMIFSAQELVSRISHDMT 221 Query: 238 LLPGDIILTGTPGGVGVYRNP 258 LLPGD+I GT GVGV + P Sbjct: 222 LLPGDLIAVGTSVGVGVMKEP 242 >UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Burkholderia phytofirmans PsJN|Rep: Fumarylacetoacetate (FAA) hydrolase - Burkholderia phytofirmans PsJN Length = 346 Score = 94.7 bits (225), Expect = 2e-18 Identities = 59/181 (32%), Positives = 91/181 (50%), Gaps = 5/181 (2%) Query: 98 PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 157 P+ F + S + P+ I + + + E+EL +VIG++ V A ++V I Sbjct: 151 PYFFQRPNSCIAPPDGEIHAESGTEE-LDWELELGIVIGRRGRHVAREDAPNFVAACLIL 209 Query: 158 QDIG--ATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQK 215 D+ A + ++ + L GK M P GP++V + IG L ++ S+NG Q Sbjct: 210 NDVTDRALIYRQDFPGADWLRGKGMPASMPAGPYLVPASVIGEIDALRLRLSVNGEVMQD 269 Query: 216 SNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 275 I +P +I LS+ + L PGD+I TGTP G G R FLQ GDVI +EI+ + Sbjct: 270 ELAGDMILDVPRLIEYLSSRVELRPGDVIATGTPAGTGAERG--RFLQDGDVIRAEIDGL 327 Query: 276 G 276 G Sbjct: 328 G 328 >UniRef50_A6E756 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Pedobacter sp. BAL39|Rep: Fumarylacetoacetate hydrolase family protein - Pedobacter sp. BAL39 Length = 332 Score = 94.3 bits (224), Expect = 3e-18 Identities = 63/212 (29%), Positives = 98/212 (46%), Gaps = 24/212 (11%) Query: 96 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 155 + P + + + GP + I+ D + + E+E+ +VIGKK + ++ A DY+ GY Sbjct: 109 QYPIFYFTNHNAIQGPGE-IECMPDHFQKLDFELEVAIVIGKKGRNITAAEADDYIAGYM 167 Query: 156 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI------------GNPQNLN 203 I D+ A + + + L K D IGPW+VT DE+ G NL Sbjct: 168 IMNDMSARTLQMEEMLLNLGPAKGKDFSTVIGPWLVTPDELEVYKTAAKSGHTGISYNLE 227 Query: 204 VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG--------GVGVY 255 +KC +NG Q N +II R + +LPGD+I +GT G G G+ Sbjct: 228 MKCLVNGQQVSSGNMADMDWTFAEIIERCAYGADILPGDVIGSGTVGTGCFLELNGTGLL 287 Query: 256 RNP---PEFLQPGDVITSEIENIGTFETRVEE 284 P P++LQ GDV+ EI +G + + Sbjct: 288 NEPDFKPQWLQDGDVVEMEITGLGHLSNTIRK 319 >UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Moritella sp. PE36|Rep: Fumarylacetoacetate hydrolase family protein - Moritella sp. PE36 Length = 231 Score = 93.5 bits (222), Expect = 6e-18 Identities = 57/182 (31%), Positives = 93/182 (51%), Gaps = 4/182 (2%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 KV+C+G NY DH E PE +F K +++V + + L +D+ + E+E+ ++ Sbjct: 30 KVVCIGRNYLDHIRELGNDVPEQALLFIKPSTSLVALDKPLPLPVDLGECHN-ELEVALL 88 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 192 I +K S + + G + D+ D + + K KA D CP+ P+I Sbjct: 89 IKSPITKGTSIVLSELIWGVGLGLDLTLRDLQSSLKGQGHPWERAKAFDNACPVTPFIPL 148 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252 + E G+ NL+ S+N +Q+ T + I ++ ++ TLLPGDI+LTGTP GV Sbjct: 149 A-EFGDVNNLDFTLSVNDQLRQQGCTANMMRSIESLLTEITACFTLLPGDIVLTGTPAGV 207 Query: 253 GV 254 GV Sbjct: 208 GV 209 >UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1; Vibrio splendidus 12B01|Rep: Putative uncharacterized protein - Vibrio splendidus 12B01 Length = 274 Score = 93.5 bits (222), Expect = 6e-18 Identities = 66/209 (31%), Positives = 98/209 (46%), Gaps = 16/209 (7%) Query: 74 DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133 +KV VG+N+ H PP + F K PS+++ + I++ ++ V E EL V Sbjct: 80 EKVFAVGMNFASHLASPADAPPPM---FLKLPSSLILTGEVIQVPPK-ARNVHFEGELVV 135 Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193 VIG++ S+ A + G T+ DI W+ Q L KA D F P+G IV Sbjct: 136 VIGRELSQASEEEAEQAIFGVTVGNDITERSWQGADL--QWLRAKASDGFGPVGNTIVRG 193 Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 + N + + +NG Q+ NT+ IHK +++ LS TL PGD+I GTPG Sbjct: 194 IDYNN---IELTTRVNGKVVQQENTSFMIHKPRKVVSYLSYYFTLKPGDLIFMGTPGRTY 250 Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRV 282 L D ++ IE +GT V Sbjct: 251 A-------LSDKDQVSVTIEGVGTVVNEV 272 >UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase precursor; n=4; Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase precursor - Polaromonas naphthalenivorans (strain CJ2) Length = 245 Score = 93.1 bits (221), Expect = 7e-18 Identities = 67/226 (29%), Positives = 111/226 (49%), Gaps = 19/226 (8%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 ++G T PV +V C+G NY+ + + P E+P F K + VV + L Sbjct: 19 VAGSTAVFPV---GRVFCIGRNYR--WSQDEAMPQEMPAWFMKPANAVVHAHGV--LPYP 71 Query: 121 VSKAVVC-EIELTVVIGKKASKVDSSHAFDY-VLGYTIAQDIGATDWEKNKKIS--QLLL 176 + C EIEL V IG+ + + + + GY D+ D ++ K + Sbjct: 72 PATGDFCHEIELVVAIGRGGRDIAPAQVEPHHIWGYAAGLDLTRRDLQQQAKRAGGPWEA 131 Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236 KA D P P +V + G+P+ V ++NG+++Q+++ + + + +++A LS + Sbjct: 132 AKAFDHSAPCTP-LVPAAACGHPRQGAVWLTVNGIERQRADVSGLLWPVAELVAMLSRSV 190 Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TL+PGD+I TGTP GVG LQPGDV+ + +G F V Sbjct: 191 TLMPGDLIYTGTPAGVGP-------LQPGDVVQGGVAGVGQFSMTV 229 >UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Nocardioides sp. JS614|Rep: Fumarylacetoacetate (FAA) hydrolase - Nocardioides sp. (strain BAA-499 / JS614) Length = 280 Score = 93.1 bits (221), Expect = 7e-18 Identities = 60/189 (31%), Positives = 93/189 (49%), Gaps = 7/189 (3%) Query: 97 LPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTI 156 LP + P TV+GP D I ++ + E+EL VIG+ + +A D+V GYTI Sbjct: 91 LPAYYKGLPDTVIGPEDEIPWPA-YTQRLDHELELAAVIGRPGKDITEDNALDHVFGYTI 149 Query: 157 AQDIGATDWEKNKKISQLLLGKA--MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQ 214 D+ A D + + + GKA D +GP IVT+DE+ +P ++ ++ +NG + Sbjct: 150 WNDLSARDVQAGELPVGMGPGKAKDWDGSNVLGPCIVTADEV-DPHDIELEVRVNGERWG 208 Query: 215 KSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT-PGGVGVYRNPPEFLQPGDVITSEIE 273 +NT H +I S + L PG+++ +GT GG GV +L P D + E Sbjct: 209 GANTRDMHHTFESMIVYASQALMLRPGEVLGSGTATGGSGVELG--RWLAPADTVEMEAS 266 Query: 274 NIGTFETRV 282 IG V Sbjct: 267 GIGVLRNVV 275 >UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7; Saccharomycetales|Rep: Uncharacterized hydrolase YNL168C - Saccharomyces cerevisiae (Baker's yeast) Length = 259 Score = 93.1 bits (221), Expect = 7e-18 Identities = 76/231 (32%), Positives = 113/231 (48%), Gaps = 41/231 (17%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP------------NDTIK-LKMD- 120 K++C+G NY H +E + P+ PF F K S++V P N T L D Sbjct: 11 KIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLSSSLVKTTRPANSTFNGLNEDG 70 Query: 121 -------VSKAVVC--EIELTVVIGKKAS---KVDSSHAFDYVLGYTIAQDIGATDW--E 166 + + V EIEL +++ K S K+ +D + G +A D+ A + E Sbjct: 71 TNPGPIFIPRGVKVHHEIELALIVSKHLSNVTKMKPEEVYDSISGVALALDLTARNVQDE 130 Query: 167 KNKKISQLLLGKAMDTFCPIGPWIVTSDEIG----NPQNL-NVKCSINGVQKQKSNTNQF 221 KK + K DTF PI IV+ ++ N Q++ VKCS+NG +Q TN Sbjct: 131 AKKKGLPWTISKGFDTFMPISA-IVSREKFSSYKSNLQDIFRVKCSVNGQLRQDGGTNLM 189 Query: 222 IHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEI 272 +H + I+ +S +++L PGDIILTGTP GVG L+PGD + E+ Sbjct: 190 LHPLHKILQHISTMISLEPGDIILTGTPAGVGE-------LKPGDRVHCEL 233 >UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Marinomonas sp. MWYL1|Rep: Fumarylacetoacetate (FAA) hydrolase - Marinomonas sp. MWYL1 Length = 235 Score = 92.7 bits (220), Expect = 1e-17 Identities = 64/215 (29%), Positives = 104/215 (48%), Gaps = 14/215 (6%) Query: 75 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVV--GPNDTIKLKMDVSKAVV-CEIE 130 +V CVG NY +H +E P + PF F K S VV G +++ + ++ + E+E Sbjct: 26 RVYCVGRNYAEHSKEMGDDPERDPPFFFAKDSSCVVPAGFSESTLITYPMATSQFEYEVE 85 Query: 131 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN--KKISQLLLGKAMDTFCPIGP 188 L + IGK + + + +LGY + D+ D + KK +GK+ D PI P Sbjct: 86 LVIAIGKGGRNLTLQQSREAILGYAVGLDMTRRDLQSQAKKKGRPWEVGKSFDESAPISP 145 Query: 189 WIVTSDEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247 ++ +D + N + +NG KQ S+ I ++I +LS V L PGD+I+TG Sbjct: 146 ILLKTDLLADNVSKAEIGLKVNGDLKQISHVTNLTWSIEEVICKLSEVFELRPGDLIMTG 205 Query: 248 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 TP VG + GD + + +E++G V Sbjct: 206 TPENVGA-------VVVGDEMQAWVEHLGEIRVSV 233 >UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3; Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA) hydrolase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 320 Score = 91.5 bits (217), Expect = 2e-17 Identities = 60/201 (29%), Positives = 96/201 (47%), Gaps = 13/201 (6%) Query: 96 ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 155 E+P + P +V+GP D + + +A+ E+E+ +IG+ S + A ++ GYT Sbjct: 98 EIPTFYFGNPYSVIGPQDPVAVPPGC-EALDFELEVAAIIGRAGSNLAPEEARGHIAGYT 156 Query: 156 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI-----GNPQNLNVKCSING 210 I D A D ++++ L K D +GPWIVTSDE+ +L ++ +NG Sbjct: 157 ILNDWSARDLQRHEMQIGLGPAKGKDFANTLGPWIVTSDELEPYRRDGRLHLEMEVFVNG 216 Query: 211 VQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG-------VGVYRNPPEFLQ 263 + +++A S + PGD++ +GT G V R P L+ Sbjct: 217 EKLGDDTLANMAWSFEELVAYASRGTWVRPGDVLGSGTCGSGCLAELWGRVGRQEPPLLE 276 Query: 264 PGDVITSEIENIGTFETRVEE 284 PGDV+ +E IGT E RV E Sbjct: 277 PGDVVRMTVEGIGTIENRVVE 297 >UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Sphingomonas wittichii RW1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Sphingomonas wittichii RW1 Length = 276 Score = 91.5 bits (217), Expect = 2e-17 Identities = 60/209 (28%), Positives = 95/209 (45%), Gaps = 15/209 (7%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K + +G+NY+ E + PE P ++ + P+ ++G D I L D VVCE EL V Sbjct: 76 KYVGIGINYRATAEALGMAMPEEPVVYVRPPNCIIGDGDRIVLPADGD--VVCEGELAAV 133 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDI-GATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193 IG++ + +V+GYT+ D+ + K+K L K D F P+GP I T Sbjct: 134 IGRRGRDIAEGDVAAHVIGYTLTNDLMDVARFHKDK--GNPSLAKGRDGFAPLGPCIATG 191 Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253 ++ + + +NG + Q + + ++ +S MTL PGD++ G P Sbjct: 192 LDLATAE---LATFVNGARVQAGFARDMLFGVERCVSHISRFMTLEPGDVVALGCP---- 244 Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRV 282 P + PGD I IGT V Sbjct: 245 ---PTPARIAPGDRIEIGCAPIGTLANEV 270 >UniRef50_Q22Y44 Cluster: Fumarylacetoacetate hydrolase family protein; n=4; Oligohymenophorea|Rep: Fumarylacetoacetate hydrolase family protein - Tetrahymena thermophila SB210 Length = 233 Score = 91.5 bits (217), Expect = 2e-17 Identities = 69/189 (36%), Positives = 95/189 (50%), Gaps = 11/189 (5%) Query: 74 DKVLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPN--DTIKLKMDVSKAVVCEIE 130 +K+L +G NY H +E + P+ P IF K P + V PN K++ V EIE Sbjct: 14 NKILAIGKNYVKHVKEMGGSEVPKEPVIFQK-PHSSVLPNIQKGQKVQFFTKNEVHHEIE 72 Query: 131 LTVVIGKKAS----KVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL--LGKAMDTFC 184 L ++ K+AS + + DYV GY +A D+ + + K + L K D F Sbjct: 73 LGFMMSKEASHKSFQKSGENWQDYVGGYFLALDLTDRNLQAAAKKAGFPWDLSKGQDKFL 132 Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244 PI +I +++ +P NL + ING QK NT KI D I S MTL PGD+ Sbjct: 133 PISSFI-PKEKVQDPYNLTLHLRINGKTIQKDNTGIMHFKIKDQIEYASKFMTLYPGDLF 191 Query: 245 LTGTPGGVG 253 LTGTP GVG Sbjct: 192 LTGTPDGVG 200 >UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family protein; n=15; Ascomycota|Rep: Fumarylacetoacetate hydrolase family protein - Aspergillus fumigatus (Sartorya fumigata) Length = 235 Score = 90.2 bits (214), Expect = 5e-17 Identities = 74/227 (32%), Positives = 111/227 (48%), Gaps = 12/227 (5%) Query: 66 LKA-PVHGNDKVLCVG-LNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND-TIKLKMDVS 122 LKA P H + G LN +E T P+ PF F K PS+++ P + + L VS Sbjct: 3 LKARPSHSHQNPRRNGSLNKSQLQKELNNTKPKQPFFFLKPPSSILLPREGPVLLPKGVS 62 Query: 123 KAVVCEIELTVVIGKKASKVDSSH---AFDYVLGYTIAQDIGATDW--EKNKKISQLLLG 177 + E+EL +V+GK +D + A D + Y +A D+ + E KK + Sbjct: 63 --LHYEVELALVMGKTVRDLDPNDEKGALDAIRSYLLAIDMTGRNVQDEAKKKGLPWSIA 120 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 K DTF PI I + I +P N ++ S+ +Q +T +++IP +A +S VMT Sbjct: 121 KGFDTFLPISEEIPKA-RIPDPHNAFLRLSVGSQLRQADSTGLMLYRIPRQLAEISRVMT 179 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284 L GD++LTGTP GVG + +V EIE G E V++ Sbjct: 180 LEKGDLVLTGTPKGVGEVKAGDVMKASIEVDGKEIEE-GRIEVEVKD 225 >UniRef50_Q5KVH0 Cluster: Hypothetical conserved protein; n=2; Geobacillus|Rep: Hypothetical conserved protein - Geobacillus kaustophilus Length = 260 Score = 89.8 bits (213), Expect = 7e-17 Identities = 55/189 (29%), Positives = 92/189 (48%), Gaps = 11/189 (5%) Query: 94 PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 153 PPE P ++ K +T+ + L V K + L +VIG+ A++V A D+V G Sbjct: 75 PPEGPVLYMKPANTINAHRRPVLLPRWV-KHLQAAPALGLVIGRTAARVRREQALDFVFG 133 Query: 154 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213 YTI D+ ++++ + +A D F P+GPWIV +E +L + +NG Sbjct: 134 YTIVNDLSIPHEQRHRPAVK---EQARDGFAPVGPWIVPKEEASPLSSLTARVYVNGRLV 190 Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273 Q+++ ++F + +A ++ MTL PGD++ P + GDV+ EIE Sbjct: 191 QRADPSRFRLPVEQWLAEVTEFMTLYPGDVLFFSWPADA-------PLVTAGDVVRIEIE 243 Query: 274 NIGTFETRV 282 IG E + Sbjct: 244 RIGVLENEI 252 >UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7; Proteobacteria|Rep: Faa-hydrolase family protein - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 265 Score = 89.4 bits (212), Expect = 9e-17 Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 7/185 (3%) Query: 75 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTV--VGPNDTIKLKMD-VSKAVVCEIE 130 ++ C+G NY H E P E PF F K + V P + ++K EIE Sbjct: 59 RIYCIGRNYAAHAREMGSDPTREPPFFFQKPSDAIQYVAPGKVVDHPYPTLTKNYHYEIE 118 Query: 131 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK--NKKISQLLLGKAMDTFCPIGP 188 L I K + +A +V GY + D+ D + K+ +GK+ D PIGP Sbjct: 119 LVAAINKGGKNISVENALQHVFGYAVGLDMTRRDLQAAMKKEEKPWEIGKSFDMSAPIGP 178 Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248 + IGN + +NG KQ ++ Q I + + I+ LS L+PGDII +GT Sbjct: 179 LHPVAS-IGNFTEGKIWLKVNGQVKQSADLKQMIWSVAEQISNLSKAFELMPGDIIYSGT 237 Query: 249 PGGVG 253 P VG Sbjct: 238 PENVG 242 >UniRef50_A3PZU8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; n=8; Actinomycetales|Rep: 5-carboxymethyl-2-hydroxymuconate delta-isomerase - Mycobacterium sp. (strain JLS) Length = 529 Score = 89.0 bits (211), Expect = 1e-16 Identities = 61/212 (28%), Positives = 107/212 (50%), Gaps = 11/212 (5%) Query: 64 ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 I++ + + KV+ V LNY+ ++ P P F K P+++ ++ ++ Sbjct: 36 ISVAEVIERSRKVIAVHLNYRSRAAQRGRFPGH-PSYFLKPPTSLALSGRPVERPAG-TR 93 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183 + E E+ +VIG++ +V +++D V A D+G D K S L K D F Sbjct: 94 LLAFEGEIALVIGRRTRRVSPENSWDCVQFVCAANDLGVYDLRTVDKGSNLR-SKGGDGF 152 Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243 PIGP ++++ I +P L V+ +NG Q +T+ + +IA LS ++TL GD+ Sbjct: 153 TPIGPQLLSARGI-DPARLRVRTWVNGRLAQDGDTSDLLFPFTQLIADLSQLITLEAGDV 211 Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 275 ILTGTP G V + PGD + +++++ Sbjct: 212 ILTGTPAGSSV-------VAPGDTVEVQVDSV 236 >UniRef50_A0GBX8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2; Burkholderia|Rep: Fumarylacetoacetate (FAA) hydrolase - Burkholderia phytofirmans PsJN Length = 257 Score = 89.0 bits (211), Expect = 1e-16 Identities = 53/196 (27%), Positives = 92/196 (46%), Gaps = 12/196 (6%) Query: 63 GITLKAPVHG-------NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTI 115 G+ +APV G ND+ L H K PP+ P ++ K +T+ G + Sbjct: 32 GMACRAPVRGAVYGTLLNDRAALAALGDAVHAAPYK-APPQAPVLYLKPRNTLAGHRARV 90 Query: 116 KLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL 175 + D + V L +V+G+ A++V + AFDY+ GYT+ D+ + + Sbjct: 91 GVPDD-ALGVEVGASLGIVVGRTATRVGVAQAFDYIAGYTLVADLSVPHASVYRPSVRF- 148 Query: 176 LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNV 235 +A D FC +GP +V S + P NL ++ + ++T + + ++A +++ Sbjct: 149 --RARDGFCVVGPVVVASHHVATPDNLAIRVQLGSRDAFTASTASSVRNVAQLVADVTDF 206 Query: 236 MTLLPGDIILTGTPGG 251 MTL GD+I G P G Sbjct: 207 MTLSAGDVITLGVPHG 222 >UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep: Putative hydrolase - Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 /FAM18) Length = 218 Score = 88.6 bits (210), Expect = 2e-16 Identities = 57/181 (31%), Positives = 89/181 (49%), Gaps = 5/181 (2%) Query: 76 VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 135 + C+G NY H EE K P P +F K +++ TI L + S+ V E EL +++ Sbjct: 16 IFCIGRNYAAHIEELKNEIPSEPVVFMKPSGSILNSGGTILLP-EFSRDVQFECELVLLV 74 Query: 136 GKKASKV-DSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVT 192 GK + + + V GY + D+ A D + + K L L K + + Sbjct: 75 GKDSDGMGEGEDILGCVAGYGVGLDLTARDIQCHLKAQGLPWLKAKGFRHSACVSDF-AA 133 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252 +D IGNP+ + NGV KQ+ +T I+ I +I+ +L+ L GD++ TGTP GV Sbjct: 134 ADRIGNPEKVLFSLKQNGVLKQRGDTGLMIYPIREILHKLAADYGLGKGDLVFTGTPSGV 193 Query: 253 G 253 G Sbjct: 194 G 194 >UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; n=1; Plesiocystis pacifica SIR-1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase - Plesiocystis pacifica SIR-1 Length = 287 Score = 88.2 bits (209), Expect = 2e-16 Identities = 64/213 (30%), Positives = 99/213 (46%), Gaps = 12/213 (5%) Query: 68 APVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 127 AP KVL +G NY H +E P P F K PS ++ + L ++ + Sbjct: 75 APPLAPTKVLAIGRNYAAHAKELGNEVPSSPLSFFKPPSCLLASGQPLSLPRGYAR-IDM 133 Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187 E EL +VIG++A ++ ++ A+ +V Y + DI D +++ K Q K D F P+ Sbjct: 134 EAELVLVIGRRARQIAAADAWAHVGAYLMGNDISCRDLQRSDK--QWTRAKGFDGFGPVS 191 Query: 188 PWIVTSD--EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245 + S E+ L V+ + Q T+ I +P ++ LS MTL GD+I Sbjct: 192 AFARLSPAAELPPVDALRVRGLLGDELVQDGPTSAMIFDVPTLLEHLSACMTLEVGDLIF 251 Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTF 278 TGTP GV L+PG V E++ +F Sbjct: 252 TGTPAGVSA-------LEPGMVTRVELDGPPSF 277 >UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; n=5; Alphaproteobacteria|Rep: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 265 Score = 87.8 bits (208), Expect = 3e-16 Identities = 65/211 (30%), Positives = 94/211 (44%), Gaps = 14/211 (6%) Query: 75 KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133 +V CVG NY H E P E PF F K +V I + + EIEL V Sbjct: 62 RVFCVGRNYAGHAREMGGDPNREAPFYFTKPADALVPGGGDIPYPPGTAN-LHHEIELVV 120 Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTFCPIGPWIV 191 + + K A + GY + D+ D + K LGKA + PI P +V Sbjct: 121 ALSRSVYKCTPDEASTAIFGYAVGLDMTRRDLQFAARDKGRPWCLGKAFEFSAPISP-LV 179 Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251 +D ++ ++ +NG +Q + N+ I +P++IA LS L GD+I TGTP G Sbjct: 180 RADAPKLAGSITLE--VNGQIRQSGDLNEMIWSVPEVIAHLSQYYHLGAGDLIFTGTPEG 237 Query: 252 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 282 VG + GDV+ IE +G E + Sbjct: 238 VGP-------VVAGDVLRGAIEGVGELEVHI 261 >UniRef50_A6D592 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Vibrio shilonii AK1|Rep: Fumarylacetoacetate (FAA) hydrolase - Vibrio shilonii AK1 Length = 264 Score = 87.8 bits (208), Expect = 3e-16 Identities = 66/220 (30%), Positives = 98/220 (44%), Gaps = 20/220 (9%) Query: 65 TLKAPV-HGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123 TL AP+ HG+ V VGLN++ H PE+ F + V + + D + Sbjct: 64 TLLAPITHGS--VYAVGLNFRSHAGNSGAAKPEI--FFKSIDA--VRLSGALSFP-DEAN 116 Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183 V E EL +VIGK + +A V GY D+ W+ Q K F Sbjct: 117 NVHFEGELVIVIGKTCHDTSNQNALSCVFGYLAGNDLTERSWQGQDL--QWWRAKGATGF 174 Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243 P+ +I T+ +IGN + + +NG Q+ IH +P I++ +S +TL PGD+ Sbjct: 175 GPVSNFITTNVDIGNQE---IVTRLNGKIMQQETLANMIHNVPTIVSYISKYITLRPGDM 231 Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 I GTPG R+ GD ++ IE IG +E Sbjct: 232 IFAGTPGRTRALRS-------GDNVSVSIEGIGQVSNTIE 264 >UniRef50_A5V6I4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1; Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate (FAA) hydrolase - Sphingomonas wittichii RW1 Length = 350 Score = 87.8 bits (208), Expect = 3e-16 Identities = 57/189 (30%), Positives = 94/189 (49%), Gaps = 6/189 (3%) Query: 97 LPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASK-VDSSHAFDYVLGYT 155 +PFI+ ++VG ND + L + E EL +V+ A + +D A +++ GYT Sbjct: 140 MPFIWLATHGSLVGANDDVPLPQ-IGANHDWEAELCLVLAGGAPRYMDPEEAHEHIAGYT 198 Query: 156 IAQDI--GATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213 I D+ G + K + + K+ F P+GP++V + +L +K +NG K Sbjct: 199 IVNDMHTGELFSRDDIKWNADWIAKSPPGFKPVGPYVVPRQFFPDIDDLVIKLWVNGELK 258 Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273 Q N I +A S + +LPGD+++TG+P G G + N +FL PGD + EI Sbjct: 259 QDWPVNDMIFSSEHYVAYASERLKILPGDLLMTGSPPGNGAFHN--QFLVPGDTMDIEIS 316 Query: 274 NIGTFETRV 282 +G R+ Sbjct: 317 YLGRQRNRL 325 >UniRef50_Q5UY90 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isomerase; n=4; Halobacteriaceae|Rep: 2-hydroxyhepta-24-diene-1,7-dioate isomerase - Haloarcula marismortui (Halobacterium marismortui) Length = 238 Score = 87.8 bits (208), Expect = 3e-16 Identities = 59/207 (28%), Positives = 93/207 (44%), Gaps = 17/207 (8%) Query: 78 CVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGK 137 CVG NY ++ PE P F K P+ ++ I + EL VIG+ Sbjct: 48 CVGRNYAATNDQMDYDRPEEPDFFIKPPTALLAHEQNIPYPPFTDELTYAG-ELAAVIGE 106 Query: 138 KASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIG 197 + +D + D V GYTI D+ A D + KA D P+GPWI T+ + Sbjct: 107 RCHDIDPADVSDAVRGYTILNDVDALDQQGRTA------RKAFDGSGPLGPWIETAVD-- 158 Query: 198 NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRN 257 P ++++ IN ++Q +NT++ + +++A LS T PGD++ G+P G Sbjct: 159 -PTDIDMYTDINDERRQSANTSEMLFGPHEVVAYLSKRFTFRPGDVVAFGSPANPGT--- 214 Query: 258 PPEFLQPGDVITSEIENIGTFETRVEE 284 + P D I + +GT V E Sbjct: 215 ----VAPDDTIEITYDGVGTLRNSVVE 237 >UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8; Xanthomonadaceae|Rep: Fumarylacetoacetate hydrolase - Xanthomonas oryzae pv. oryzae Length = 290 Score = 87.4 bits (207), Expect = 4e-16 Identities = 66/218 (30%), Positives = 101/218 (46%), Gaps = 23/218 (10%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPP-------ELPFIFNKFPSTVVGPNDTIKLKMDV 121 PVH ++ CVG N+ DH E + P + F + VVG D I Sbjct: 76 PVH---RIYCVGRNFADHAREMGASAPASKAERGQPTFFMKPADAIVVGHGDQIPYPPG- 131 Query: 122 SKAVVCEIELTVVIGKKA--SKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL--LG 177 +K + E+EL V +G A ++ A + GY + D+ D + K L + Sbjct: 132 TKELHHEVELVVALGSDAPAGELPVEQAERLIYGYGVGLDLTRRDLQAAAKAKGLPWDIA 191 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 K D PI +V + E+G + LN+ +NG +Q+S +Q I +P+I+ LS + Sbjct: 192 KGFDHSAPISE-LVHAGEVGVLEALNLSLEVNGQVRQQSLLDQMIWNVPEILHALSKLYA 250 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 275 L GD+I GTP GVG L PGD ++ +EN+ Sbjct: 251 LRAGDLIFMGTPAGVGP-------LLPGDQFSARLENV 281 >UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family protein; n=1; Alcanivorax borkumensis SK2|Rep: Fumarylacetoacetate hydrolase family protein - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 233 Score = 87.4 bits (207), Expect = 4e-16 Identities = 65/218 (29%), Positives = 101/218 (46%), Gaps = 15/218 (6%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 + G + PV KV+CVG NY DH +E P+ P +F K + + ++ + L + Sbjct: 20 IDGSAMNMPV---GKVVCVGRNYADHAKELGNETPDAPILFMKPATALTSLHEPLVLP-E 75 Query: 121 VSKAVVCEIELTVVIGKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKN--KKISQLLLG 177 V E+E+ V+IGK+ K H V Y I D+ + + +K Sbjct: 76 GQGPVHHEVEMVVLIGKRIRKETRLDHVRFSVAAYGIGLDLTLREVQNQLKEKGHPWERA 135 Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237 KA D P+ +I + I Q+L V +N KQ +T Q + ++++ +S T Sbjct: 136 KAFDGAAPVSGFI-DARGISVRQDLGVTLELNDAVKQHGHTGQMLFPTFELLSEISQTFT 194 Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 275 L PGD++ TGTP GVG L GD T+ + NI Sbjct: 195 LEPGDVVFTGTPAGVGP-------LNSGDKFTARLGNI 225 >UniRef50_A4EDA6 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Roseobacter sp. CCS2|Rep: Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Roseobacter sp. CCS2 Length = 257 Score = 87.0 bits (206), Expect = 5e-16 Identities = 65/192 (33%), Positives = 92/192 (47%), Gaps = 6/192 (3%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120 ++G TL P K + + N+ E KL P+ P F K S++ GPN + L + Sbjct: 41 MAGNTLLPPCEPG-KFIGLWNNFHAAAERNKLDIPQHPLFFLKPLSSLAGPNAQVALPPN 99 Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATD-WEKNKKISQLLLGKA 179 + + VV E EL +VIGK + A +LGYT DI A D ++ Q K Sbjct: 100 IGR-VVYEGELGIVIGKTCKNISVDAAESAILGYTCVNDITALDILFEDPSFPQWTRAKG 158 Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239 D F IGP I T N ++L VK +N ++Q + I I+++LS MTL Sbjct: 159 YDGFGVIGPVIQTDL---NWRDLTVKVMVNDRERQSYPASDMIMNPAQIVSQLSTDMTLE 215 Query: 240 PGDIILTGTPGG 251 PGD+I GT G Sbjct: 216 PGDVIACGTSIG 227 >UniRef50_A0UKA6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=6; Burkholderia|Rep: Fumarylacetoacetate (FAA) hydrolase - Burkholderia multivorans ATCC 17616 Length = 426 Score = 86.6 bits (205), Expect = 6e-16 Identities = 57/190 (30%), Positives = 93/190 (48%), Gaps = 10/190 (5%) Query: 69 PVHGNDKVLCVGLNYKDHCEEQKLTPPELPF--IFNKFPSTVVGPNDTIKLKMDVSKAVV 126 PV N + +C G NY+ H E + P F IF K PS +V + + V + + Sbjct: 172 PVTANQQFVCQGANYRRHMIESGMDPDAKQFNMIFTKAPSCIVAADSRVVKPRHV-RFLD 230 Query: 127 CEIELTVVIGKKASK---VDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183 EIEL +V+ + ++ V ++ +YV G I D A D + + Q GK+ TF Sbjct: 231 YEIELGLVLKRDITRHQPVTDANLHEYVAGIAIVNDYSARDVQIPQM--QFYKGKSFRTF 288 Query: 184 CPIGPWIVTSDEIGNPQ--NLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241 P+GP++ + P+ L + S+NG +Q+ +T ++ + + LS V L G Sbjct: 289 GPVGPYLCLLERHDFPKLKTLELTLSVNGTVRQQDSTANLVYGPAETLTELSGVHDLGAG 348 Query: 242 DIILTGTPGG 251 D++ TGTP G Sbjct: 349 DLLATGTPAG 358 >UniRef50_A0QDN9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=4; Actinomycetales|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Mycobacterium avium (strain 104) Length = 313 Score = 86.2 bits (204), Expect = 8e-16 Identities = 59/210 (28%), Positives = 105/210 (50%), Gaps = 11/210 (5%) Query: 61 LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPF-IFNKFPSTVVGPNDTIKLKM 119 + G+ L +PV +V+ N+ H ++ + P +P F K ++ GP D I +K Sbjct: 52 VEGLNLLSPVTAPCRVVAQMTNFASHVKDAGMDPNTIPLTFFRKASGSITGPFDDI-VKP 110 Query: 120 DVSKAVVCEIELTVVIGKK---ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176 D + + E+E+ +VIG++ + V ++ DY G + D+ A D + K +Q Sbjct: 111 DHVRFLDYEVEIGLVIGRELPVGAAVSEANLADYTAGAVVTNDVSARDIQLPK--TQFYE 168 Query: 177 GKAMDTFCPIGPWIVT--SDEIGNPQNLNVKCSINGVQKQKSNTN-QFIHKIPDIIARLS 233 K+ TF P+GP +V +DE+ +L ++ +NG +Q + I+ + L+ Sbjct: 169 SKSYPTFTPVGPALVLLDADELKRFGDLRLQLRVNGQVRQDMRVDGDMIYPPVQALQALA 228 Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQ 263 L PGD++LTGTP G + PP+ +Q Sbjct: 229 RFQRLDPGDLVLTGTPVGTAL-SAPPKPVQ 257 >UniRef50_Q1VYL9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=16; Bacteroidetes|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Psychroflexus torquis ATCC 700755 Length = 204 Score = 85.8 bits (203), Expect = 1e-15 Identities = 62/211 (29%), Positives = 97/211 (45%), Gaps = 10/211 (4%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K++C+G NY H E K PE P +F K S+V+ N+ + +K V E+E+ V Sbjct: 2 KLICIGRNYAKHISELKNEKPEHPVVFLKPDSSVLLKNNPFIIPA-FTKEVHHEVEILVK 60 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA--MDTFCPIGPWIVT 192 I K + + A Y + D A D + K L KA D IG + Sbjct: 61 INKVGKHIQTKFAHKYYDEIGLGIDFTARDIQNQLKEQGLPWEKAKGFDGAAVIGETWLP 120 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252 D + N++ + N Q +T++ + +I ++IA +S TL GD+I TGTP GV Sbjct: 121 KDRFQDLNNIDFRLEKNKTAVQSGSTSEMLWRIDELIAHVSEYFTLKIGDVIFTGTPAGV 180 Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 283 G ++ GD + IE+ F +V+ Sbjct: 181 G-------RVEEGDHLEGFIEDTSCFSIQVK 204 >UniRef50_A2U2G0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1; Polaribacter dokdonensis MED152|Rep: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Polaribacter dokdonensis MED152 Length = 203 Score = 85.4 bits (202), Expect = 1e-15 Identities = 56/177 (31%), Positives = 85/177 (48%), Gaps = 5/177 (2%) Query: 75 KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134 K+L +G NY ++ FIF+K P + + N + ++ ++ E+EL V Sbjct: 2 KILGIGSNYVTDLKDIPEKKKGKKFIFSK-PESSLAVNCDVPYPSSITNELIYEVELVVK 60 Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ--LLLGKAMDTFCPIGPWIVT 192 IGK+ + A Y+ I D A D N + ++ K D PI + Sbjct: 61 IGKEGKNITKEEANSYISEIAIGIDYTAKDILTNARETKHPWEFAKGFDGAAPISSFKPI 120 Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 249 +D + N++ ING +KQKSNT I+ DII+ +S MTL PGD+I TGTP Sbjct: 121 TDY--DLANIDFDLKINGEEKQKSNTAYMINNFADIISFISEYMTLQPGDLIFTGTP 175 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.317 0.138 0.405 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 319,996,435 Number of Sequences: 1657284 Number of extensions: 12974200 Number of successful extensions: 28902 Number of sequences better than 10.0: 336 Number of HSP's better than 10.0 without gapping: 313 Number of HSP's successfully gapped in prelim test: 23 Number of HSP's that attempted gapping in prelim test: 27901 Number of HSP's gapped (non-prelim): 371 length of query: 285 length of database: 575,637,011 effective HSP length: 100 effective length of query: 185 effective length of database: 409,908,611 effective search space: 75833093035 effective search space used: 75833093035 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 72 (33.1 bits)
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