SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001068-TA|BGIBMGA001068-PA|IPR002529|Fumarylacetoacetate
(FAA) hydrolase
         (285 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A...   364   1e-99
UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to fumarylace...   247   2e-64
UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase domain-co...   245   9e-64
UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105 pr...   237   3e-61
UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p ...   237   3e-61
UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B...   224   2e-57
UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   220   4e-56
UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   216   6e-55
UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1; ...   215   1e-54
UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   213   4e-54
UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   207   3e-52
UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   206   5e-52
UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   202   6e-51
UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   197   3e-49
UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   195   1e-48
UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   194   2e-48
UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   194   3e-48
UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   188   1e-46
UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   188   2e-46
UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   187   3e-46
UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   186   4e-46
UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   185   1e-45
UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   183   4e-45
UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   183   5e-45
UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   182   9e-45
UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family pr...   180   4e-44
UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   177   2e-43
UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family pr...   177   2e-43
UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   177   3e-43
UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   176   5e-43
UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17; S...   176   5e-43
UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   175   8e-43
UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1; ...   175   8e-43
UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   175   1e-42
UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family pr...   174   2e-42
UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre...   174   2e-42
UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family pr...   173   6e-42
UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   172   7e-42
UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   172   7e-42
UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4; Eu...   171   1e-41
UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase;...   171   2e-41
UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family pr...   170   3e-41
UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctiona...   169   5e-41
UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   169   5e-41
UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Re...   169   7e-41
UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase ...   169   7e-41
UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   169   7e-41
UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   168   1e-40
UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   167   2e-40
UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   167   3e-40
UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   167   4e-40
UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   167   4e-40
UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   166   5e-40
UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp...   166   5e-40
UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila melanogaste...   166   6e-40
UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   165   9e-40
UniRef50_O53242 Cluster: POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-D...   165   1e-39
UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase;...   165   1e-39
UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   165   1e-39
UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   164   2e-39
UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4; Th...   164   2e-39
UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep: B...   164   3e-39
UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family pr...   162   8e-39
UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase...   162   1e-38
UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3; Burkholderiale...   161   1e-38
UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1; ...   161   1e-38
UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2; ...   161   2e-38
UniRef50_Q67K64 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d...   161   2e-38
UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium di...   161   2e-38
UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   160   3e-38
UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   159   6e-38
UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep...   159   7e-38
UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   159   1e-37
UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   158   1e-37
UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus ter...   158   1e-37
UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   158   2e-37
UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   157   2e-37
UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   157   4e-37
UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   156   5e-37
UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   156   5e-37
UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1; ...   155   9e-37
UniRef50_Q88Y59 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioateisom...   155   2e-36
UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia farci...   155   2e-36
UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   154   3e-36
UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   153   4e-36
UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1, 7...   153   4e-36
UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   153   4e-36
UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   152   9e-36
UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep: Lm...   152   1e-35
UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   151   2e-35
UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   151   3e-35
UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358; ...   150   3e-35
UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family pr...   150   3e-35
UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family pr...   150   5e-35
UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase...   150   5e-35
UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4; Pezizomy...   149   6e-35
UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   149   1e-34
UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3; c...   148   2e-34
UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   146   4e-34
UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584...   146   6e-34
UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   146   6e-34
UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   146   7e-34
UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   145   1e-33
UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   145   1e-33
UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   144   2e-33
UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family pr...   144   2e-33
UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   144   2e-33
UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9;...   144   2e-33
UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   144   3e-33
UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein; ...   144   3e-33
UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   143   4e-33
UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   143   5e-33
UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA) hydr...   142   7e-33
UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1; F...   142   7e-33
UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   141   2e-32
UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   141   2e-32
UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom...   141   2e-32
UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1;...   141   2e-32
UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   140   4e-32
UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1; ...   140   5e-32
UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation bifu...   139   6e-32
UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   139   9e-32
UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family pr...   139   9e-32
UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISO...   138   1e-31
UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   137   3e-31
UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase;...   137   3e-31
UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   137   3e-31
UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family pr...   137   3e-31
UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   137   3e-31
UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   136   6e-31
UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   136   6e-31
UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_030014...   135   1e-30
UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   135   1e-30
UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   135   1e-30
UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate i...   134   2e-30
UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   133   4e-30
UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   133   4e-30
UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   132   7e-30
UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family pr...   132   7e-30
UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family pr...   132   1e-29
UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   132   1e-29
UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD - P...   131   2e-29
UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   131   2e-29
UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF; ...   131   2e-29
UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6;...   131   2e-29
UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2; Proteobacteria...   130   3e-29
UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate iso...   130   3e-29
UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   130   4e-29
UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family pr...   130   4e-29
UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...   130   4e-29
UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albic...   129   7e-29
UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   129   7e-29
UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   128   1e-28
UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6; Pezizomy...   128   2e-28
UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate hydratase...   128   2e-28
UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   127   3e-28
UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4; Actinomy...   126   5e-28
UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14; ...   126   8e-28
UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3; E...   126   8e-28
UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   125   1e-27
UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5; E...   125   1e-27
UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM - P...   125   1e-27
UniRef50_Q4JXJ3 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d...   124   3e-27
UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase...   124   3e-27
UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6; Asc...   123   5e-27
UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation bifu...   122   1e-26
UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   122   1e-26
UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albic...   121   2e-26
UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   120   3e-26
UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41; Gam...   119   7e-26
UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1; ...   118   2e-25
UniRef50_Q2S2N6 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d...   118   2e-25
UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   118   2e-25
UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid...   118   2e-25
UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   117   3e-25
UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...   116   5e-25
UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1; ...   116   7e-25
UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3;...   115   2e-24
UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   114   2e-24
UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase domain-co...   114   2e-24
UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   113   4e-24
UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family pr...   113   6e-24
UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   112   8e-24
UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   112   1e-23
UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep...   111   1e-23
UniRef50_Q8G4X7 Cluster: Possible 2-hydroxyhepta-2,4-diene-1,7-d...   111   2e-23
UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   111   3e-23
UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   110   3e-23
UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate Delta...   110   5e-23
UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   110   5e-23
UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2; ...   110   5e-23
UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   109   1e-22
UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   109   1e-22
UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella per...   108   2e-22
UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate hydratase/2-oxohept...   108   2e-22
UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1; ...   107   2e-22
UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4; ...   107   3e-22
UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep:...   106   6e-22
UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   106   7e-22
UniRef50_A1HJ09 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...   106   7e-22
UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep...   105   1e-21
UniRef50_Q3INL8 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d...   104   3e-21
UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...   103   4e-21
UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   103   4e-21
UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family pr...   103   4e-21
UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium ja...   103   7e-21
UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=...   103   7e-21
UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP020...   102   9e-21
UniRef50_UPI00006CDD7C Cluster: fumarylacetoacetate hydrolase fa...   101   2e-20
UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family pr...   101   2e-20
UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   101   2e-20
UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation; 2-h...   100   4e-20
UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1; ...   100   4e-20
UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...   100   5e-20
UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family pr...   100   8e-20
UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1; ...    98   2e-19
UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    98   3e-19
UniRef50_Q9X4X0 Cluster: DitH; n=8; Proteobacteria|Rep: DitH - P...    97   3e-19
UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep:...    97   3e-19
UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    97   6e-19
UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|R...    95   2e-18
UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    95   2e-18
UniRef50_A6E756 Cluster: Fumarylacetoacetate hydrolase family pr...    94   3e-18
UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family pr...    93   6e-18
UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1; ...    93   6e-18
UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase pre...    93   7e-18
UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    93   7e-18
UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7;...    93   7e-18
UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    93   1e-17
UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    91   2e-17
UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...    91   2e-17
UniRef50_Q22Y44 Cluster: Fumarylacetoacetate hydrolase family pr...    91   2e-17
UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family pr...    90   5e-17
UniRef50_Q5KVH0 Cluster: Hypothetical conserved protein; n=2; Ge...    90   7e-17
UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7; Prot...    89   9e-17
UniRef50_A3PZU8 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...    89   1e-16
UniRef50_A0GBX8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    89   1e-16
UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep:...    89   2e-16
UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...    88   2e-16
UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...    88   3e-16
UniRef50_A6D592 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    88   3e-16
UniRef50_A5V6I4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    88   3e-16
UniRef50_Q5UY90 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate isom...    88   3e-16
UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8; Xan...    87   4e-16
UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family pr...    87   4e-16
UniRef50_A4EDA6 Cluster: Putative 2-hydroxyhepta-2,4-diene-1,7-d...    87   5e-16
UniRef50_A0UKA6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    87   6e-16
UniRef50_A0QDN9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...    86   8e-16
UniRef50_Q1VYL9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...    86   1e-15
UniRef50_A2U2G0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...    85   1e-15
UniRef50_A5VDV9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    85   2e-15
UniRef50_A5V0Z8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    85   2e-15
UniRef50_Q97UR1 Cluster: 2-hydroxyhepta-2 ,4-diene-1,7-dioate is...    85   2e-15
UniRef50_Q2BPV1 Cluster: Putative uncharacterized protein; n=4; ...    85   3e-15
UniRef50_A4CE53 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...    85   3e-15
UniRef50_Q88M65 Cluster: Fumarylacetoacetate hydrolase family pr...    83   6e-15
UniRef50_Q72P81 Cluster: Fumarylacetoacetate hydrolase family pr...    83   6e-15
UniRef50_A4SV99 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    83   6e-15
UniRef50_A0QS23 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...    82   1e-14
UniRef50_Q15XL1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    81   2e-14
UniRef50_Q5P741 Cluster: Fumarylpyruvate hydrolase; n=14; Proteo...    81   4e-14
UniRef50_O86346 Cluster: POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXY...    80   7e-14
UniRef50_Q7NUB2 Cluster: Probable isomerase; n=3; Betaproteobact...    77   4e-13
UniRef50_Q1QDY9 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    77   4e-13
UniRef50_A2CBF2 Cluster: Putative uncharacterized protein; n=1; ...    77   4e-13
UniRef50_A1UG87 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    77   4e-13
UniRef50_Q89FA1 Cluster: Bll6800 protein; n=3; Proteobacteria|Re...    77   7e-13
UniRef50_Q97VT9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate iso...    76   9e-13
UniRef50_Q0LGD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    76   1e-12
UniRef50_A4F0I3 Cluster: Fumarylacetoacetate hydrolase family pr...    74   5e-12
UniRef50_Q7WPF0 Cluster: Putative fumarylacetoacetate hydrolase ...    73   6e-12
UniRef50_Q0S954 Cluster: Possible hydratase; n=3; Actinomycetale...    73   6e-12
UniRef50_A4YZ43 Cluster: Putative Fumarylacetoacetate hydrolase ...    73   1e-11
UniRef50_Q4AQ85 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    72   1e-11
UniRef50_Q4WH18 Cluster: Fumarylacetoacetate hydrolase family pr...    72   1e-11
UniRef50_Q2W964 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...    72   2e-11
UniRef50_A3SNB2 Cluster: Fumarylacetoacetate hydrolase family pr...    71   3e-11
UniRef50_A4QX03 Cluster: Putative uncharacterized protein; n=1; ...    71   3e-11
UniRef50_Q18X79 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    71   3e-11
UniRef50_Q3WGU5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    69   2e-10
UniRef50_Q02AF6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    69   2e-10
UniRef50_Q4D6U8 Cluster: Putative uncharacterized protein; n=2; ...    69   2e-10
UniRef50_Q7MXX3 Cluster: Fumarylacetoacetate hydrolase family pr...    67   4e-10
UniRef50_Q395G4 Cluster: 5-carboxymethyl-2-hydroxymuconate delta...    67   4e-10
UniRef50_Q6F7V5 Cluster: Putative uncharacterized protein; n=2; ...    66   7e-10
UniRef50_Q0SB97 Cluster: Possible fumarylacetoacetate hydrolase ...    66   7e-10
UniRef50_Q4J6K3 Cluster: 4-hydroxyphenylacetate degradation bifu...    66   7e-10
UniRef50_Q3II31 Cluster: Putative fumarylacetoacetate hydrolase ...    66   1e-09
UniRef50_Q4J7I6 Cluster: Conserved protein; n=3; Thermoprotei|Re...    66   1e-09
UniRef50_Q0AN49 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    65   2e-09
UniRef50_Q6KZ97 Cluster: Fumarylacetoacetase; n=2; Thermoplasmat...    65   2e-09
UniRef50_Q6MNK0 Cluster: Putative uncharacterized protein; n=1; ...    64   4e-09
UniRef50_Q8D6F8 Cluster: 2-keto-4-pentenoate hydratase; n=22; Pr...    62   2e-08
UniRef50_A7K1Y8 Cluster: Fumarylacetoacetate hydrolase family pr...    62   2e-08
UniRef50_Q3E159 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    61   4e-08
UniRef50_Q9CKS8 Cluster: HpaG; n=1; Pasteurella multocida|Rep: H...    60   5e-08
UniRef50_Q60C48 Cluster: Fumarylacetoacetate hydrolase family pr...    60   5e-08
UniRef50_Q8KDK4 Cluster: Fumarylacetoacetate hydrolase family pr...    60   8e-08
UniRef50_Q7UMG2 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d...    60   8e-08
UniRef50_Q5KYI4 Cluster: Hypothetical conserved protein; n=3; Ba...    60   8e-08
UniRef50_A0VBW0 Cluster: 4-hydroxyphenylacetate degradation bifu...    60   8e-08
UniRef50_Q4FWM5 Cluster: Putative uncharacterized protein; n=3; ...    59   1e-07
UniRef50_Q5B6D4 Cluster: Putative uncharacterized protein; n=1; ...    59   1e-07
UniRef50_A7D1J1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    59   1e-07
UniRef50_A1TDQ7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    59   1e-07
UniRef50_A5EF32 Cluster: Putative Fumarylacetoacetate (FAA) hydr...    58   2e-07
UniRef50_Q44SK1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    57   4e-07
UniRef50_A5VED2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate de...    57   6e-07
UniRef50_A3VRL8 Cluster: Putative isomerase-decarboxylase-like p...    56   1e-06
UniRef50_A0SP98 Cluster: Fumarylacetoacetate hydrolase family pr...    54   5e-06
UniRef50_A3IA41 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    53   1e-05
UniRef50_A7QL05 Cluster: Chromosome undetermined scaffold_116, w...    52   1e-05
UniRef50_A1SUQ4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    52   2e-05
UniRef50_Q9KDZ0 Cluster: BH1071 protein; n=2; Bacillus|Rep: BH10...    52   2e-05
UniRef50_Q5V2I1 Cluster: Fumarylacetoacetate hydrolase family pr...    50   5e-05
UniRef50_Q1GRD3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    50   7e-05
UniRef50_A6Q9W9 Cluster: Fumarylacetoacetate hydrolase; n=1; Sul...    50   7e-05
UniRef50_Q5DHL1 Cluster: SJCHGC00506 protein; n=2; Schistosoma j...    49   1e-04
UniRef50_A6C0W6 Cluster: Probable 2-hydroxyhepta-2,4-diene-1,7-d...    48   2e-04
UniRef50_A3VNC8 Cluster: Possible isomerase/decarboxylase; n=1; ...    48   3e-04
UniRef50_Q0HT13 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=...    48   4e-04
UniRef50_Q2UV71 Cluster: Predicted protein; n=1; Aspergillus ory...    46   8e-04
UniRef50_A2UC21 Cluster: 2-keto-4-pentenoate hydratase/2-oxohept...    42   0.018
UniRef50_A6Q508 Cluster: Fumarylacetoacetate hydrolase family pr...    41   0.031
UniRef50_Q1IPR5 Cluster: Fe-S protein, radical SAM family; n=5; ...    40   0.096
UniRef50_A7Q3E6 Cluster: Chromosome chr13 scaffold_48, whole gen...    39   0.17 
UniRef50_Q4RJI4 Cluster: Chromosome 3 SCAF15037, whole genome sh...    38   0.39 
UniRef50_Q10JF6 Cluster: Isomerase, putative; n=10; Magnoliophyt...    36   1.6  
UniRef50_Q6FUW3 Cluster: Similarities with sp|P08640 Saccharomyc...    36   1.6  
UniRef50_Q5B250 Cluster: Putative uncharacterized protein; n=1; ...    36   1.6  
UniRef50_Q4X003 Cluster: Alpha-L-arabinofuranosidase A; n=7; Pez...    36   1.6  
UniRef50_Q600A8 Cluster: Glucose-6-phosphate isomerase; n=3; Myc...    35   2.7  
UniRef50_Q6YRJ1 Cluster: Putative uncharacterized protein; n=1; ...    34   4.8  
UniRef50_Q0TRU3 Cluster: Putative permease; n=1; Clostridium per...    34   4.8  
UniRef50_Q22GI1 Cluster: Putative uncharacterized protein; n=1; ...    33   6.3  
UniRef50_Q245B0 Cluster: Putative uncharacterized protein; n=1; ...    33   8.3  

>UniRef50_Q2F601 Cluster: Fumarylacetoacetate hydrolase isoform A;
           n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase
           isoform A - Bombyx mori (Silk moth)
          Length = 330

 Score =  364 bits (896), Expect = 1e-99
 Identities = 161/288 (55%), Positives = 216/288 (75%), Gaps = 3/288 (1%)

Query: 1   MKLLQFSYKNSD-GIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXX 59
           MKL+QFSYK+S   IR G+L+GD++VDINK D  LP+TL+++L+                
Sbjct: 43  MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 102

Query: 60  X--LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKL 117
              LS +TL AP+HG DK+LC+GLNYKDHC+EQ LTPP +P +F+KF ST++GP+  +++
Sbjct: 103 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 162

Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177
           + DV+K V  E+EL VV+G++AS V    A  +V GYT+AQDI A DW+K K + Q LLG
Sbjct: 163 RTDVTKKVDWEVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLG 222

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           K+MDTFCP+GP ++TSDE+G    L V CS+NGV KQ S+T Q +H IP ++ R+S+VMT
Sbjct: 223 KSMDTFCPLGPCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMT 282

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285
           L+PGD+ILTGTPGGVG+YR PPE+LQPGDV+TSEIE IG F+ R+E+F
Sbjct: 283 LVPGDLILTGTPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 330


>UniRef50_UPI000051A4FC Cluster: PREDICTED: similar to
           fumarylacetoacetate hydrolase domain containing 2A
           isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar
           to fumarylacetoacetate hydrolase domain containing 2A
           isoform 2 - Apis mellifera
          Length = 334

 Score =  247 bits (605), Expect = 2e-64
 Identities = 127/289 (43%), Positives = 179/289 (61%), Gaps = 8/289 (2%)

Query: 1   MKLLQFSYKNSDGIRAG--FLDGDNVVDINKEDPKLPSTLIELLK--TNXXXXXXXXXXX 56
           M+ +QF+ KN      G   + G +++ ++  D ++P+TL + L+   +           
Sbjct: 46  MRFVQFTGKNGGPQHLGVQLVQGGDIIAVSAVDSRIPNTLKKFLEGGDDLLKKAKRIVAE 105

Query: 57  XXXXLSGITLK--APVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT 114
               +  + +   APV   DK+ CVGLNY  HC+EQ ++PPE P IF+KF S ++GP D 
Sbjct: 106 GRSVIPEVEVNFLAPVTRMDKLACVGLNYIGHCKEQGVSPPESPVIFSKFASNIIGPRDN 165

Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS-Q 173
           I L   +S  V  E EL +VIGKK   ++++   DY+ GYTIAQDI A DW+K+K+   Q
Sbjct: 166 IMLP-PISDKVDWEAELAIVIGKKCKALNNNEGEDYIFGYTIAQDITARDWQKSKRNGGQ 224

Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233
            LLGKAMDTFCP+GP +VT + I +  NL VK  +NG  KQ  NT++ I K  +I+A +S
Sbjct: 225 FLLGKAMDTFCPLGPAVVTKEAISDINNLTVKTWVNGNIKQDGNTSELIFKPHEIVAYIS 284

Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
             MTLLPGD+ILTGTP GVG  R PPE+LQ GDV+ +EI+ +G    +V
Sbjct: 285 QFMTLLPGDVILTGTPSGVGFTRKPPEYLQRGDVLETEIQGLGRLRNKV 333


>UniRef50_Q6P2I3 Cluster: Fumarylacetoacetate hydrolase
           domain-containing protein 2B; n=41; cellular
           organisms|Rep: Fumarylacetoacetate hydrolase
           domain-containing protein 2B - Homo sapiens (Human)
          Length = 314

 Score =  245 bits (600), Expect = 9e-64
 Identities = 123/288 (42%), Positives = 169/288 (58%), Gaps = 7/288 (2%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDN--VVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXX 58
           M+L+QF   +  G   G   G+   V+++N  DP LP T+ + L+               
Sbjct: 27  MRLVQFRAPHLVGPHLGLETGNGGGVINLNAFDPTLPKTMTQFLEQGEATLSVARRALAA 86

Query: 59  XX----LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT 114
                  S +T  APV   DKV+CVG+NY DHC+EQ +  P+ P IF+KF S++VGP D 
Sbjct: 87  QLPVLPWSEVTFLAPVTWPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPYDE 146

Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174
           + L    S+ V  E+EL VVIGKK   + ++ A  +V G+T+A D+ A DW   +   Q 
Sbjct: 147 VVLPPQ-SQEVDWEVELAVVIGKKGKHIKATDAMAHVAGFTVAHDVSARDWLTRRNGKQW 205

Query: 175 LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSN 234
           LLGK  DTFCP+GP +VT D + +P NL + C +NG   Q SNTNQ + K  D+IA +S 
Sbjct: 206 LLGKTFDTFCPLGPALVTKDSVADPHNLKICCRVNGEVVQSSNTNQMVFKTEDLIAWVSQ 265

Query: 235 VMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
            +T  PGD+ILTGTP GVGV+R PP FL+ GD +  EIE +G    +V
Sbjct: 266 FVTFYPGDVILTGTPPGVGVFRKPPVFLKKGDEVQCEIEELGVIINKV 313


>UniRef50_UPI0000E821BC Cluster: PREDICTED: similar to CGI-105
           protein; n=2; Gallus gallus|Rep: PREDICTED: similar to
           CGI-105 protein - Gallus gallus
          Length = 406

 Score =  237 bits (579), Expect = 3e-61
 Identities = 106/221 (47%), Positives = 149/221 (67%), Gaps = 1/221 (0%)

Query: 62  SGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV 121
           +G+ L AP+   +KV+CVGLNY+DHC EQ +  P+ P IF+KFPS + GP D I    + 
Sbjct: 186 AGVRLLAPIDDPEKVICVGLNYRDHCLEQDVKVPKEPLIFSKFPSAIAGPFDDIVHPAES 245

Query: 122 SKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMD 181
           S+ V  E+EL  +IGK    +  S A ++++G+T+A D+ A DW+  +   Q LLGK  D
Sbjct: 246 SE-VDWEVELAAIIGKTGRHIQESVAMEHIVGFTVANDVSARDWQMRRNGRQWLLGKTFD 304

Query: 182 TFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241
           TFCPIGP IVT D + +  NL ++CS+NG   Q S+TNQ I ++P ++A +S  +TL PG
Sbjct: 305 TFCPIGPAIVTKDSVTDVHNLRIRCSVNGQLMQSSSTNQLIFRLPQLVAWVSQFVTLRPG 364

Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           D++LTGTP GVGV+R PP FL+PGD +  EIE +GT   +V
Sbjct: 365 DVLLTGTPPGVGVFRKPPMFLKPGDEVQCEIEELGTICNKV 405


>UniRef50_Q95SI7 Cluster: GH23390p; n=7; Coelomata|Rep: GH23390p -
           Drosophila melanogaster (Fruit fly)
          Length = 293

 Score =  237 bits (579), Expect = 3e-61
 Identities = 108/213 (50%), Positives = 145/213 (68%), Gaps = 1/213 (0%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           +TL  P+    K++C+GLNY+DHC+EQ    P+ P  F+KF + +VGP D + +    S 
Sbjct: 73  VTLLPPLTDPGKIICIGLNYQDHCDEQNKPTPKEPLFFSKFNNALVGPQDNV-IAHAASS 131

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183
            +  E+EL  VIGK A +V  S A DYV GY++AQDI A DW+K +   Q L+GK+MDTF
Sbjct: 132 KIDWEVELVCVIGKVARQVPKSQAMDYVFGYSVAQDISARDWQKERNGGQFLMGKSMDTF 191

Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243
            P+GP +V    + +  NLN+K  +NGV+KQ  NT   I K+ D+I RLS  +TLLPGDI
Sbjct: 192 LPLGPAVVHKSLVPDVYNLNLKTWVNGVEKQNGNTGNLIFKLDDVINRLSQTITLLPGDI 251

Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
           I+TGTP GVG++R PPEFLQPGDV+ SEI  +G
Sbjct: 252 IVTGTPKGVGMHRTPPEFLQPGDVVQSEIVGLG 284


>UniRef50_Q2F600 Cluster: Fumarylacetoacetate hydrolase isoform B;
           n=1; Bombyx mori|Rep: Fumarylacetoacetate hydrolase
           isoform B - Bombyx mori (Silk moth)
          Length = 360

 Score =  224 bits (547), Expect = 2e-57
 Identities = 97/158 (61%), Positives = 125/158 (79%)

Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187
           E+EL VV+G++AS V    A  +V GYT+AQDI A DW+K K + Q LLGK+MDTFCP+G
Sbjct: 203 EVELCVVVGREASCVREEDALQHVAGYTVAQDISARDWQKEKNMGQFLLGKSMDTFCPLG 262

Query: 188 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247
           P ++TSDE+G    L V CS+NGV KQ S+T Q +H IP ++ R+S+VMTL+PGD+ILTG
Sbjct: 263 PCVLTSDEVGAAVELRVSCSLNGVLKQSSSTAQLVHSIPSLLHRISSVMTLVPGDLILTG 322

Query: 248 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285
           TPGGVG+YR PPE+LQPGDV+TSEIE IG F+ R+E+F
Sbjct: 323 TPGGVGMYRQPPEYLQPGDVLTSEIEKIGAFDVRIEKF 360



 Score =  145 bits (352), Expect = 1e-33
 Identities = 63/127 (49%), Positives = 91/127 (71%), Gaps = 3/127 (2%)

Query: 1   MKLLQFSYKNSD-GIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXX 59
           MKL+QFSYK+S   IR G+L+GD++VDINK D  LP+TL+++L+                
Sbjct: 43  MKLVQFSYKDSPKNIRVGYLEGDDIVDINKADSSLPTTLLQILRNGDLEKVKKLKSTKPA 102

Query: 60  X--LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKL 117
              LS +TL AP+HG DK+LC+GLNYKDHC+EQ LTPP +P +F+KF ST++GP+  +++
Sbjct: 103 TIPLSSVTLTAPIHGVDKILCIGLNYKDHCQEQNLTPPPVPMVFSKFSSTIIGPDQPVRI 162

Query: 118 KMDVSKA 124
           + DV+K+
Sbjct: 163 RTDVTKS 169


>UniRef50_A4A1V1 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase; n=1;
           Blastopirellula marina DSM 3645|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acidhydratase -
           Blastopirellula marina DSM 3645
          Length = 284

 Score =  220 bits (537), Expect = 4e-56
 Identities = 116/278 (41%), Positives = 155/278 (55%), Gaps = 3/278 (1%)

Query: 7   SYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXXL--SGI 64
           +Y++  G RA    GD+ +D++  D  LP+ +  LL                     +G 
Sbjct: 5   TYQSEAGPRAAVARGDDFIDLHHTDHTLPTDMKSLLALGDVAREKVLAAREHGDPIPAGS 64

Query: 65  TLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 124
            +  P+    KV+CVGLNY DH +E   T  + P IFNKFPS ++  +D I L  + S+ 
Sbjct: 65  RILTPIINPQKVICVGLNYADHAKETGATVGDEPVIFNKFPSALIADHDEIHLPPESSQ- 123

Query: 125 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 184
           V  E EL V IG     +    A  +V GY    DI A DW+K K   Q LLGK  DTF 
Sbjct: 124 VDYEAELVVAIGTAGKHIPQGEAMSHVGGYCCGNDISARDWQKGKPGKQWLLGKTFDTFA 183

Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244
           P+GP + T DEI +P NL ++C +NG   Q+S+T+Q I KI  +I+ LSNV+ L PGD+I
Sbjct: 184 PLGPVLYTPDEIADPNNLAIRCRLNGETMQESSTSQLIFKIDFLISYLSNVVMLQPGDLI 243

Query: 245 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
            TGTP GVGV R+P  FLQPGD +  EIE +G    RV
Sbjct: 244 FTGTPHGVGVARDPQVFLQPGDQVEVEIEGLGLLTNRV 281


>UniRef50_Q9KBC8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=3; cellular organisms|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus
           halodurans
          Length = 319

 Score =  216 bits (527), Expect = 6e-55
 Identities = 102/217 (47%), Positives = 139/217 (64%), Gaps = 3/217 (1%)

Query: 67  KAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV 126
           +AP+  + K++CVG NY++H  E K   P+ P IF KF +T++GP D + L   +++ + 
Sbjct: 95  EAPILNSKKIICVGHNYREHILEMKREIPKYPVIFAKFANTIIGPEDNVPLP-SITEQLD 153

Query: 127 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPI 186
            E EL  VIGKKA  V    A DYV GYTI  DI A D ++  +  Q L GK +D   P+
Sbjct: 154 YEAELAFVIGKKAKDVAKEDALDYVAGYTIVNDITARDLQR--RTIQWLQGKTLDGSLPM 211

Query: 187 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 246
           GPW+VT DEI NP  L +  S+NG ++Q+SNT   +  I D++  LS +MTL PGD++ T
Sbjct: 212 GPWLVTKDEIPNPHQLEITLSVNGEERQRSNTKNLVFSIQDLVVFLSGIMTLEPGDVVCT 271

Query: 247 GTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           GTPGGVGV R P  FLQ GDV+  E+E +GT E RV+
Sbjct: 272 GTPGGVGVAREPQLFLQDGDVVRIELEKVGTLENRVK 308


>UniRef50_Q54BF3 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 305

 Score =  215 bits (524), Expect = 1e-54
 Identities = 115/284 (40%), Positives = 159/284 (55%), Gaps = 17/284 (5%)

Query: 15  RAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX------LSGITLKA 68
           R G L  ++++D+   D  +P+ +   L  N                     +    +KA
Sbjct: 24  RLGALLENSIIDLCSADKSIPNDMRSFLSLNSTDKWSKVINVINNINNRRIPIENCKIKA 83

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128
           P+    K++C+GLNYK+H  E K+  P+ P +F+KF + + GPND+I +K   S  V  E
Sbjct: 84  PIEPG-KIICIGLNYKEHANEAKMAIPKEPIVFSKFDNAICGPNDSI-IKPVESDEVDYE 141

Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188
           +EL VVIGK+A  V  S A  YV GYT+  D+ A DW+  K  SQ LLGK  DTF PIGP
Sbjct: 142 VELVVVIGKQAKNVSESDALQYVAGYTVGNDVSARDWQLRKNNSQWLLGKTFDTFAPIGP 201

Query: 189 WIVTSDEIG--------NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
            IV + E+         +P NL++KC++NG   Q S T +FI  I  +++ LS + TL P
Sbjct: 202 SIVINPEVAALSDDTYFDPNNLSIKCTLNGQVVQNSTTKEFIFNIQTVVSYLSKLFTLNP 261

Query: 241 GDIILTGTPGGVGVYRNP-PEFLQPGDVITSEIENIGTFETRVE 283
           GDII TGTP GVG  R P P FL+ GDVI  EIE +G+    V+
Sbjct: 262 GDIIFTGTPSGVGFIRKPNPIFLKSGDVIKCEIEELGSLVNNVK 305


>UniRef50_A6CF17 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Planctomyces maris DSM 8797|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Planctomyces maris DSM 8797
          Length = 290

 Score =  213 bits (520), Expect = 4e-54
 Identities = 118/290 (40%), Positives = 163/290 (56%), Gaps = 10/290 (3%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDNVV---DINKEDPKLPSTLIELLKTNX----XXXXXXX 53
           MKL     +N   + A  +D DN +   D++  D  LP +L  +L               
Sbjct: 1   MKLATIQTENGIQV-ASVIDQDNKLTFFDLSAFDENLPRSLKGILAVEGGLERAKAAAEQ 59

Query: 54  XXXXXXXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND 113
                  ++G TL AP+    KVLC+GLNY+DH EE  +  P+ P  F+KF S+V G   
Sbjct: 60  AQQADRQITG-TLLAPIPSPGKVLCIGLNYRDHAEETGMPFPDEPVCFSKFSSSVTGSGQ 118

Query: 114 TIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ 173
            I++   V++ V  E EL  VIGK    V  ++A DYV GY    D+ A DW+  +   Q
Sbjct: 119 PIRIP-SVAREVDYEAELVAVIGKTCRNVTQANASDYVAGYMNGHDVSARDWQIGRPGGQ 177

Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233
            LLGK  DTF P GP++VT+DEI N  +L++K ++NG   Q SNT++FI  I ++IA +S
Sbjct: 178 WLLGKTADTFAPTGPYLVTADEIKNANSLSIKLTLNGEVLQNSNTDKFIFTIEEVIAFVS 237

Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
            ++TL PGDII TGTP GVG+ R PP +LQPGD    EI+ +G     VE
Sbjct: 238 QILTLEPGDIIFTGTPPGVGMARKPPVYLQPGDQACIEIQGLGMLHNTVE 287


>UniRef50_Q7UKL0 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Pirellula sp.|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Rhodopirellula baltica
          Length = 342

 Score =  207 bits (505), Expect = 3e-52
 Identities = 103/214 (48%), Positives = 131/214 (61%), Gaps = 1/214 (0%)

Query: 66  LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125
           L  PV   +K+LC+GLNY DH  E     P LP +F+KF S +VG    I L   +S  V
Sbjct: 123 LLPPVTCPEKILCIGLNYLDHAIETGAEKPSLPVVFSKFNSALVGHGQDIVLPK-ISDKV 181

Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185
             E EL VVIGK    VD++ A D V GY +  D+ + DW+K +   Q L+GK+ DTF P
Sbjct: 182 DYEAELVVVIGKTVRHVDANEAMDAVFGYAVGHDVSSRDWQKGRPGGQWLVGKSFDTFAP 241

Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
           +GP +VT+DEI +P NL ++  ING   Q+S T+Q I  IP +IA LS  MTL PGD+I 
Sbjct: 242 LGPAVVTADEISDPGNLPIRLHINGETLQESKTDQLIFDIPALIAHLSKFMTLKPGDLIF 301

Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFE 279
           TGTP GVG  R PP +L PGD    EI+ IG  E
Sbjct: 302 TGTPSGVGDARTPPRYLAPGDRCVVEIDGIGRLE 335


>UniRef50_A1WX00 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=2; Ectothiorhodospiraceae|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Halorhodospira halophila (strain DSM 244 / SL1)
           (Ectothiorhodospirahalophila (strain DSM 244 / SL1))
          Length = 316

 Score =  206 bits (503), Expect = 5e-52
 Identities = 101/226 (44%), Positives = 136/226 (60%), Gaps = 9/226 (3%)

Query: 64  ITLKAPV-HGNDKVLCVGLNYKDHCEEQK------LTPPELPFIFNKFPSTVVGPNDTIK 116
           +T  AP+ H    V+C+GLNY DH  E +      L  PE P +F K  ++V GP D   
Sbjct: 88  LTFLAPLPHPPRNVICLGLNYADHARESQQAKGDELALPEAPVVFTKATTSVAGPYDDFI 147

Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176
           L   V+  +  E+EL VVIG+    +    A  +V GYT+  D+ A D +   K  Q  L
Sbjct: 148 LDPSVTSELDWEVELAVVIGRGGRHIREQDALQHVFGYTVVNDLSARDLQFRHK--QFFL 205

Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236
           GK++D  CP+GPWI T++ + NP NL + C IN   +Q+S+T + +  IP IIA LS VM
Sbjct: 206 GKSVDGSCPMGPWITTANAVPNPHNLALSCRINDTTEQQSHTGEMVFSIPRIIAELSRVM 265

Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           TL+PGDII TGTP GVG  R PP FLQ GD++TSE+E +GT   R+
Sbjct: 266 TLIPGDIIATGTPAGVGFARTPPRFLQAGDIVTSEVEGLGTLRNRI 311


>UniRef50_Q1AZJ6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Rubrobacter xylanophilus DSM
           9941|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Rubrobacter xylanophilus (strain DSM
           9941 / NBRC 16129)
          Length = 293

 Score =  202 bits (494), Expect = 6e-51
 Identities = 106/232 (45%), Positives = 137/232 (59%), Gaps = 9/232 (3%)

Query: 61  LSGITLKAPV-HGNDKVLCVGLNYKDHCEE-------QKLTPPELPFIFNKFPSTVVGPN 112
           L  + L AP+      V C+G NY  H EE       Q    PE P  F+K  +TV+GP+
Sbjct: 58  LDEVRLLAPIPQPRRNVFCMGWNYLTHFEEGRGRREGQGEELPEYPTFFDKPTTTVIGPH 117

Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS 172
           D I    + S+ +  E EL VVIG+    + +  A D+V GYT A D+ A D ++     
Sbjct: 118 DDIPFDPNFSEKIDYEAELAVVIGRSGRSIPAGEAMDHVFGYTAANDVTARDVQRRHG-G 176

Query: 173 QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 232
           Q L GK MD  CP+GPWIVT+DEI + QNL V+C +NGVQKQ SNT   +  +  +I  L
Sbjct: 177 QWLKGKGMDGSCPLGPWIVTADEIPDVQNLQVQCRVNGVQKQNSNTRFMVFPVARLIEEL 236

Query: 233 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           S  MTLLPGD++LTGTP GVG  R PPEFL+PGD +T  +E +G    RV E
Sbjct: 237 SLAMTLLPGDVLLTGTPEGVGYARTPPEFLRPGDEVTVYVEGVGEISNRVVE 288


>UniRef50_A7HTC6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Parvibaculum lavamentivorans DS-1
          Length = 291

 Score =  197 bits (480), Expect = 3e-49
 Identities = 109/284 (38%), Positives = 147/284 (51%), Gaps = 7/284 (2%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX 60
           MKL  FS   S  +R G +  D +VD++K  P+LP  +  L+                  
Sbjct: 1   MKLATFSEGGS--VRIGVVRDDGIVDLSKAAPELPRDMKSLIGNEAALARAREVAKGGAA 58

Query: 61  L--SGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLK 118
           L  S + L AP+    KVL +GLNY+DH EE     PE    FNK  + + GP   I L 
Sbjct: 59  LPLSAVKLLAPIPNPGKVLAIGLNYRDHVEESGQPMPEHQVWFNKQHNCITGPYADIALP 118

Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGK 178
             VS  +  E E+  VIGK+   V    A + + GY +  D+   DW+      Q+  GK
Sbjct: 119 -SVSAFLDYEAEMCFVIGKRCKHVPKERAHEVIAGYFVGDDVSVRDWQLRTNTWQI--GK 175

Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTL 238
           + DT  PIGPWIVT DE+G+P  L++KC +NG  +Q SNT   I    D IA L+   TL
Sbjct: 176 SFDTHGPIGPWIVTPDEVGDPHALDIKCWVNGELRQNSNTKHLIFDCFDQIAHLTQAFTL 235

Query: 239 LPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
             GD+I TGT GG+G    P + L+ GDV+  E+E +G  E RV
Sbjct: 236 DIGDVIFTGTSGGIGAAMKPMQLLKEGDVVRVEVEKLGYIENRV 279


>UniRef50_Q01WN8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Solibacter usitatus Ellin6076|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Solibacter usitatus (strain Ellin6076)
          Length = 269

 Score =  195 bits (475), Expect = 1e-48
 Identities = 98/216 (45%), Positives = 136/216 (62%), Gaps = 3/216 (1%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           ++G+ L++P+    K++C+GLNY+DH EE K+  PE P +F K+ +TV G    I L  +
Sbjct: 47  VAGMKLRSPLQRPGKIICIGLNYRDHAEEAKMPIPETPTVFAKWGNTVTGHQHPIVLPKN 106

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
            S+    E EL VVIGK    +  ++  ++V GYTI  D+ A D++     SQ  +GK  
Sbjct: 107 -SRKPDYEAELAVVIGKGGRHIAEANWREHVFGYTILNDVSARDFQM--ATSQWTIGKTF 163

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           DTF PIGPWIVT+DEI +P  L +  ++N V  Q SNT+  I  IP +IA LS+VM+L P
Sbjct: 164 DTFAPIGPWIVTTDEIEDPGALRISLTLNSVTMQDSNTSNLIFGIPKLIAYLSSVMSLEP 223

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
           GDII TGTP GVG  + PP +L PGDV   ++  IG
Sbjct: 224 GDIISTGTPAGVGFAQKPPRWLVPGDVCAIQVGGIG 259


>UniRef50_A5V084 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Roseiflexus|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Roseiflexus sp. RS-1
          Length = 288

 Score =  194 bits (473), Expect = 2e-48
 Identities = 109/283 (38%), Positives = 151/283 (53%), Gaps = 10/283 (3%)

Query: 7   SYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXXLSGITL 66
           +Y++S+ +  G L GD VV +    P + S LI+                    LS +TL
Sbjct: 5   TYRDSESVHLGALRGDEVVSLADVAPDMLS-LIDAGPAGLEAARAAVERGAGVPLSAVTL 63

Query: 67  KAPV-HGNDKVLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKM 119
            AP+      V+C+G+NY  H  E      ++   PE P  F K   TV GP+D I L  
Sbjct: 64  LAPIPRPRQNVICLGMNYVAHTIESYRARGREPKMPEYPVFFTKAAHTVCGPDDDIPLDP 123

Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179
            V+  +  E+EL  +IGK    V    A +YV GYTI  DI A D +   +  Q   GK+
Sbjct: 124 KVTNELDYEVELAFIIGKAGMNVPRDEAMEYVFGYTIVNDISARDLQSRHQ--QFFKGKS 181

Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
           +   CP+GP IVT+DEI NP  L ++  +NG  +Q S+T   I  IP II  LS  M L 
Sbjct: 182 LYRACPMGPCIVTTDEIPNPAGLGIRLRLNGETRQDSHTGDLIFDIPAIIEHLSLGMPLE 241

Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           PG I+ TGTP GVG+ R PPE+++PGDV+ +EI++IG    R+
Sbjct: 242 PGMIVATGTPAGVGLGRTPPEYMRPGDVMEAEIDSIGILRNRI 284


>UniRef50_Q8ENN7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Oceanobacillus iheyensis|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Oceanobacillus iheyensis
          Length = 301

 Score =  194 bits (472), Expect = 3e-48
 Identities = 96/224 (42%), Positives = 138/224 (61%), Gaps = 3/224 (1%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L+ I L  P+    KV+CVG NY +H  E K   PE P +F KF + ++GP + I     
Sbjct: 80  LNEIQLGMPLGTARKVICVGKNYAEHVAEMKSEIPEFPVLFAKFDNAIIGPEEEIHYS-S 138

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           +++ +  E+ELT+VIG++AS V    A DYV GYTI  D  A D +K  +  Q L GK++
Sbjct: 139 LTEKLDYEVELTIVIGREASHVFEEEALDYVAGYTIGNDTSARDLQK--RTPQWLQGKSL 196

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           D   PIGPW+VT DEI +P NL +   +N  ++Q SNT   I  +P +++ +SN++TL P
Sbjct: 197 DHTTPIGPWVVTKDEIVDPGNLTIASYVNNEKRQYSNTKHLIFSVPYLVSFISNLITLKP 256

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           GDII+TGTP GVG   +PP +++  D +  EIE IG  E  V++
Sbjct: 257 GDIIMTGTPDGVGFAMDPPGYVKDKDKVKLEIEGIGIMENMVKK 300


>UniRef50_A0KDR8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=6; Burkholderiales|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Burkholderia cenocepacia (strain HI2424)
          Length = 293

 Score =  188 bits (458), Expect = 1e-46
 Identities = 102/236 (43%), Positives = 141/236 (59%), Gaps = 15/236 (6%)

Query: 61  LSGITLKAPV-HGNDKVLCVGLNYKDHCEEQKLT-----------PPELPFIFNKFPSTV 108
           L+  T+ AP+      + CVG NY +H  E + +            PE P IF K  STV
Sbjct: 61  LAEATILAPIDQPRRNIFCVGKNYHEHAAEFQNSGFDSSAKNGEHAPEAPVIFTKPASTV 120

Query: 109 VGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN 168
           +GP+  I   + V+  +  E EL VVIGK    +  + A +YV GYT+  D  A D +K 
Sbjct: 121 IGPSAKIPRHVGVTAQLDYEAELGVVIGKGGRGIKKADAMNYVFGYTVINDFTARDLQKL 180

Query: 169 KKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDI 228
            +  Q  LGK++D FCP+GP+++TSDE+ N QN+++KC +NG  +Q SNT++ I  IP +
Sbjct: 181 HR--QWFLGKSLDGFCPMGPFVITSDEV-NGQNIDIKCWVNGELRQNSNTSKLIFDIPTL 237

Query: 229 IARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           I  LS  + L PGD+I TGTP GVG+  NPP+FLQ GDVI  EI+N+G  E  V E
Sbjct: 238 IETLSAGIELQPGDVIATGTPAGVGIGFNPPKFLQKGDVIRIEIQNVGVLENEVGE 293


>UniRef50_A7CXW5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Opitutaceae bacterium TAV2|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Opitutaceae bacterium TAV2
          Length = 279

 Score =  188 bits (457), Expect = 2e-46
 Identities = 96/208 (46%), Positives = 120/208 (57%), Gaps = 1/208 (0%)

Query: 76  VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV-SKAVVCEIELTVV 134
           +LC+GLNY+ H EE     PE P +F K  + +  P D I L   + S  V  E EL VV
Sbjct: 69  ILCIGLNYRRHAEETHARIPEFPVLFMKGVNALQNPGDPIMLPTHLRSDEVDYECELAVV 128

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IG+    V   HA DYVLGYT A D+ A DW+  +  SQ   GK  DTF P+GP IVT D
Sbjct: 129 IGRTCKNVTRDHALDYVLGYTCANDVSARDWQVKRGGSQWCRGKTFDTFAPLGPAIVTKD 188

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           EI NP  L +  +++G   Q   T+  I  +P +I  LS   TLLPG +ILTGTP GVG+
Sbjct: 189 EIPNPNALKISTTVSGEVLQDWTTSDMIFDVPALIEFLSGSTTLLPGTVILTGTPHGVGM 248

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282
            R PP +L+ GD +  EIE IG  E  V
Sbjct: 249 ARKPPRWLRAGDKVVVEIEKIGRLENPV 276


>UniRef50_Q1ATI0 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Rubrobacter xylanophilus DSM
           9941|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Rubrobacter xylanophilus (strain DSM
           9941 / NBRC 16129)
          Length = 295

 Score =  187 bits (455), Expect = 3e-46
 Identities = 93/219 (42%), Positives = 134/219 (61%), Gaps = 2/219 (0%)

Query: 66  LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125
           L APV    K++ +GLNY+DH  E     PE P +F K+ +T+VG  + +++    S+A 
Sbjct: 78  LHAPVLNPQKIIAIGLNYEDHANETGAPIPEKPIVFAKYANTLVGAGEEVRIPPITSQAD 137

Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185
             E EL VVIG++A  V    A +YV GYT   D+ + D + ++   Q    K++DTFCP
Sbjct: 138 Y-EAELAVVIGREAKNVSEEEALEYVFGYTNCNDVSSRDLQFSEG-GQWTRSKSLDTFCP 195

Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
           +GP++ T DEI +PQ+L ++  +NG   Q SNT++ I  +  +I+ LS  MTL+PGDII 
Sbjct: 196 LGPYVATRDEIPDPQSLRIRSVLNGEVMQDSNTSKMIFPVARLISFLSTGMTLVPGDIIA 255

Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           TGTP GVG  R+P  FL+ GD I+ EIE +G     V E
Sbjct: 256 TGTPAGVGFARDPKVFLKDGDEISIEIEGLGRLTNPVRE 294


>UniRef50_Q1ITZ8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Acidobacteria bacterium
           Ellin345|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 290

 Score =  186 bits (454), Expect = 4e-46
 Identities = 99/223 (44%), Positives = 133/223 (59%), Gaps = 4/223 (1%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           + G  L  PV    K++ +GLNY DH +E   + P+ P  F KF S++ GP D I+L  D
Sbjct: 69  VDGRDLDFPVAAK-KIVAIGLNYLDHAKEAGQSIPKTPLCFAKFTSSLSGPYDPIRLP-D 126

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
               V  E EL VVIGK+A +V  S A +YV GY +  D+  ++        Q   GK+ 
Sbjct: 127 AEAQVDFEGELGVVIGKRAHRVAESEAMEYVAGYVVFNDV--SERRSQFADGQWTRGKSC 184

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           DTF P GP++VT DE+ +P NL +   +NG   Q SNTNQ I KIP++I+ LS+  T  P
Sbjct: 185 DTFSPNGPYLVTRDEVADPGNLRITTRVNGAVMQDSNTNQLIFKIPELISYLSHSFTFHP 244

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           GDII TGTP GVG  R PP +L+ GD++  EIE++G    RVE
Sbjct: 245 GDIIATGTPPGVGFSRKPPLYLREGDLVEVEIESVGRIANRVE 287


>UniRef50_Q1GTC2 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Bacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 302

 Score =  185 bits (450), Expect = 1e-45
 Identities = 97/226 (42%), Positives = 134/226 (59%), Gaps = 10/226 (4%)

Query: 64  ITLKAPVHGNDK-VLCVGLNYKDHCEEQKLTP------PELPFIFNKFPSTVVGPNDTIK 116
           +TL AP+    K +  +GLNY +H  E           P+ P IF+K P+ V   ND I+
Sbjct: 77  VTLLAPIPRPRKNIFGIGLNYTEHVAESARALDTAHELPQQPVIFSKPPTAVAAWNDPIR 136

Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176
               V++ +  E EL V+IG  A  V  + A ++V GYT+  D+ A D    ++  Q ++
Sbjct: 137 HNAKVTQQLDWETELAVIIGSTARGVAEADALNHVFGYTVINDVSARDC---RRAGQWIV 193

Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236
            K  D+F P+GP IVT+DEIG+P NLN+   +NGV+KQ SNT   +  +P +IA ++ VM
Sbjct: 194 SKGQDSFAPMGPCIVTADEIGDPHNLNILTHVNGVEKQNSNTRFMLFNVPQLIADIARVM 253

Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           TL PGDII TGTP GVG  R+P EFL PGDV+   +E IGT    V
Sbjct: 254 TLEPGDIIATGTPAGVGAGRDPQEFLWPGDVVECTVEGIGTLRNPV 299


>UniRef50_Q5WIZ5 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Bacillus clausii KSM-K16|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Bacillus clausii (strain KSM-K16)
          Length = 292

 Score =  183 bits (446), Expect = 4e-45
 Identities = 93/224 (41%), Positives = 136/224 (60%), Gaps = 5/224 (2%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           +   T    +   +K++C+GLNY+ H +E     PE P +F+KF +T+ G    I +   
Sbjct: 68  IESCTFGPAIPNPEKIICIGLNYRRHADETGSPYPETPILFSKFNNTLTGHGSNIVVP-P 126

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           V++A+  E+EL +VIGK A +V    A +YVLGY  A D+ A D +   K +Q LLGK  
Sbjct: 127 VTQALDYEVELAIVIGKTAKQVTEDEALNYVLGYCTANDLSARDLQM--KTAQWLLGKTC 184

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           D FCPIGP++VT ++I +PQNL ++  +NG  KQ+SNT   I    +II+ +S   TL P
Sbjct: 185 DGFCPIGPFLVTKEDIADPQNLALETRVNGEIKQQSNTADMIFTCAEIISYVSRHFTLKP 244

Query: 241 GDIILTGTPGGV--GVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GDI+LTGTP GV  G+      +LQPGD ++  IE +GT   ++
Sbjct: 245 GDILLTGTPEGVILGLPEAERRYLQPGDTVSVHIEQLGTLTNKL 288


>UniRef50_Q2BPP6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=3; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Neptuniibacter caesariensis
          Length = 286

 Score =  183 bits (445), Expect = 5e-45
 Identities = 100/222 (45%), Positives = 127/222 (57%), Gaps = 4/222 (1%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L+ ++L APV    K L VGLNY DH EE  L  PE P  FNK  S V+GPN+ I  +  
Sbjct: 60  LNEVSLLAPVASPQKFLGVGLNYADHIEETGLDTPEFPTFFNKQSSCVIGPNEAIH-RPT 118

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           VS+ +  E EL +VIGK    V    A + + G+TI  D+   DW+   K     LGK+ 
Sbjct: 119 VSEKLDYEGELAIVIGKACRHVPYEKASEVIAGFTIVNDVSVRDWQI--KSPTWTLGKSF 176

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           DT  P+GPWIVT+DE+ NP NL +K  +N   +Q SNT   I     +I  LS V TL P
Sbjct: 177 DTHGPMGPWIVTADEV-NPHNLELKTWVNDELRQHSNTKHLIFDCYQLIETLSTVCTLQP 235

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GD+I TGT  GVGV   P  +++PGD +T EIE IG     V
Sbjct: 236 GDVIATGTSSGVGVKMKPRGYMKPGDRVTIEIEGIGKLSNPV 277


>UniRef50_Q67SA7 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Symbiobacterium thermophilum|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Symbiobacterium thermophilum
          Length = 294

 Score =  182 bits (443), Expect = 9e-45
 Identities = 93/220 (42%), Positives = 133/220 (60%), Gaps = 3/220 (1%)

Query: 63  GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122
           G+ L  PV    K+LCVGLNY+ H  E  +  P  P +F KF + V GP D + L   ++
Sbjct: 74  GLRLGPPVPRPGKILCVGLNYRAHAAEAHMAVPAYPVLFAKFQNAVAGPGDPVVLP-SIA 132

Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDT 182
           +    E EL VVIG++A +V +  A DYVLGY    D+ A   E   + SQ LLGK++D 
Sbjct: 133 EQYDYEAELVVVIGRRARRVPAEAALDYVLGYCNGNDLSAR--ELQMRTSQWLLGKSLDG 190

Query: 183 FCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGD 242
           F PIGP++VT DE+ +PQ+L ++   NG  +Q  +T   +  + ++IA +S  MTL PGD
Sbjct: 191 FLPIGPYLVTRDEVPDPQDLRIRLWRNGEIRQDGHTRNMLFPVAELIAYISRYMTLEPGD 250

Query: 243 IILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           II TGTP GV +     ++L+PGDV+  EI+ +G  E R+
Sbjct: 251 IIATGTPEGVIMGLAEKDWLKPGDVVAVEIDGLGRLENRL 290


>UniRef50_Q4FMJ2 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=2; Candidatus Pelagibacter ubique|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Pelagibacter ubique
          Length = 281

 Score =  180 bits (438), Expect = 4e-44
 Identities = 86/204 (42%), Positives = 129/204 (63%), Gaps = 2/204 (0%)

Query: 79  VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 138
           +GLNY +H +E     P+ P +FNK   ++VGPND + +    SK +  E+E+  VIGKK
Sbjct: 76  IGLNYVEHAKETGAKTPDNPVLFNKSVHSIVGPNDNVIIPK-TSKKLDHEVEIAFVIGKK 134

Query: 139 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 198
           A +V    A DY+ GY I  DI   +W+K K   Q + GK+ DTF P+GP++VT DEI +
Sbjct: 135 AKRVLEKDAQDYIFGYCICNDISEREWQKEKG-GQWVKGKSGDTFGPLGPYLVTKDEIQD 193

Query: 199 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 258
             NLN+   +NG + Q  NTNQ I     ++A +++ +TL+PGDI+ TGTP GVG+  +P
Sbjct: 194 VNNLNLTLDVNGHRHQTGNTNQMIFNFNFLVAHITSFITLMPGDIVTTGTPPGVGLGMDP 253

Query: 259 PEFLQPGDVITSEIENIGTFETRV 282
           P FL+ GD +   I+++G+  ++V
Sbjct: 254 PVFLKEGDEMKLNIDSLGSQNSKV 277


>UniRef50_A6EBW4 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase;
           n=1; Pedobacter sp. BAL39|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase -
           Pedobacter sp. BAL39
          Length = 285

 Score =  177 bits (432), Expect = 2e-43
 Identities = 88/220 (40%), Positives = 127/220 (57%), Gaps = 2/220 (0%)

Query: 66  LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125
           L +P+    K++C+GLNY DH  E     P  P +F K  + +VGP D I +     K  
Sbjct: 65  LGSPIGRPSKLVCIGLNYADHARETNAPLPPEPVVFMKSTTAIVGPFDQIMIPKGSVKTD 124

Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185
             E+EL +VIGKKAS V+ + A DYV GY +  D+   +++  +       GK  DTF P
Sbjct: 125 -WEVELAIVIGKKASYVEEAEALDYVAGYVLHNDVSEREFQIERN-GTWDKGKGCDTFAP 182

Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
           +GP++ T +EI +  NL +  S+NG   Q  NT+ FI  +P +++ +S  MTLLPGD+I 
Sbjct: 183 LGPFLATKEEIADVNNLRLWLSVNGKMMQDGNTSNFIFNVPFVVSYVSQFMTLLPGDVIS 242

Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285
           TGTP GVG+   PP +L+ GDV+   I+ +GT    V  F
Sbjct: 243 TGTPAGVGLGFKPPVYLKAGDVVELGIDGLGTSRQEVIAF 282


>UniRef50_A3IC16 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Bacillus sp. B14905|Rep:
           Fumarylacetoacetate hydrolase family protein - Bacillus
           sp. B14905
          Length = 314

 Score =  177 bits (432), Expect = 2e-43
 Identities = 84/204 (41%), Positives = 125/204 (61%), Gaps = 5/204 (2%)

Query: 76  VLCVGLNYKDHCEEQ--KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133
           ++C+G NY +H +E   +  P EL  +F K P+ +     T+ +  D+S  +  E EL +
Sbjct: 94  IMCIGKNYNEHAKEMGAEAAPKEL-MVFTKSPTAIAADGQTLSIHADLSSKMDYEGELAI 152

Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193
           VIGK+   +  + A+DYV GYTIA DI A D ++  K  Q  LGK+++  CP+GP++VT 
Sbjct: 153 VIGKRGKNIPKNLAYDYVFGYTIANDITARDLQEKHK--QFFLGKSLEGTCPLGPYLVTK 210

Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
           DEI NPQ+L V   +N   +Q  +T   +  +  +++ LS  +TL PGD+ILTGTP GVG
Sbjct: 211 DEIPNPQDLTVVTKVNDEVRQNGSTKDMMFSVETLVSILSQHVTLEPGDVILTGTPAGVG 270

Query: 254 VYRNPPEFLQPGDVITSEIENIGT 277
              NPP+FL+ GD +   I+ IGT
Sbjct: 271 KGMNPPQFLKAGDTVKVSIQGIGT 294


>UniRef50_A0VVP4 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=5; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Dinoroseobacter shibae DFL 12
          Length = 308

 Score =  177 bits (430), Expect = 3e-43
 Identities = 95/222 (42%), Positives = 128/222 (57%), Gaps = 8/222 (3%)

Query: 68  APVHGNDK-VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           AP+H   K + CVG NY +H  E       K+   E P  F K  + VVG    + +   
Sbjct: 85  APLHTPRKNIFCVGRNYAEHIAEGERAQNAKIGITEHPVYFTKPATAVVGHGGDVLIFPS 144

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           VS+ +  E+EL VVIG     +    AF +V GYTI  DI A D ++     Q   GK++
Sbjct: 145 VSEKIDYEVELAVVIGTTGRDIPKDRAFAHVFGYTILNDITARDVQRRHG-GQYFKGKSL 203

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           D  CPIGPWIVT+DEI +PQ+L++  S+NG  +Q   T+  I  IP +IA LS  +TL P
Sbjct: 204 DGSCPIGPWIVTADEITDPQDLSISLSVNGELRQNGWTHDMIFDIPTLIASLSEGLTLEP 263

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GDII TGTP GVG   +PP++L+PGD +  +I NIG  +  V
Sbjct: 264 GDIIATGTPSGVGYAMDPPQYLKPGDTVICDIANIGQLKNTV 305


>UniRef50_Q8RCZ4 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=8; cellular organisms|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Thermoanaerobacter tengcongensis
          Length = 242

 Score =  176 bits (429), Expect = 5e-43
 Identities = 100/209 (47%), Positives = 129/209 (61%), Gaps = 13/209 (6%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K +CVGLNYKDH EE     PE P +F K  + V+GP+D I L  ++S+ V  E EL VV
Sbjct: 47  KAICVGLNYKDHIEEMGDKIPEEPTLFIKPSTAVIGPDDYIILP-EMSRRVDYEGELAVV 105

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IG+KA  V    A +Y+LGYTIA D+ A D +   K  Q    K+ DTF PIGPWIVT  
Sbjct: 106 IGRKAKNVSIEEAKNYILGYTIANDVTARDLQA--KDGQWTRAKSFDTFLPIGPWIVTDL 163

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           +   P +LN+   +NG  KQKSNT   I  +  +++ +S++MTL PGD+ILTGTP GVG 
Sbjct: 164 D---PTSLNITTYVNGEVKQKSNTKYLIFNVFKLVSFISHIMTLNPGDVILTGTPSGVGP 220

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRVE 283
                  L+ GDV+T EIE IG    RV+
Sbjct: 221 -------LKSGDVVTIEIEGIGKLTNRVK 242


>UniRef50_Q4L4Y4 Cluster: Uncharacterized protein SH1982; n=17;
           Staphylococcus|Rep: Uncharacterized protein SH1982 -
           Staphylococcus haemolyticus (strain JCSC1435)
          Length = 301

 Score =  176 bits (429), Expect = 5e-43
 Identities = 107/301 (35%), Positives = 150/301 (49%), Gaps = 22/301 (7%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDNVVDINK------EDPKLPSTLIELLKTNXX------- 47
           MK L F+YK+++         D V D+ K      E    P TL+E L+ N         
Sbjct: 1   MKFLSFNYKDAESYGVKVKRKDAVWDLKKVFAEFGEGDFHPQTLLEGLQQNQTLDFQEQV 60

Query: 48  ------XXXXXXXXXXXXXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIF 101
                               + I    PV   + V+  G NY+DH  E       L ++F
Sbjct: 61  RKAVVAAEDSGKADEFKIAFNDIEFLPPVTPPNNVIAFGRNYQDHASELNHEVQRL-YVF 119

Query: 102 NKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIG 161
            K  S++ G   TI    D++  +  E EL +VIGK   K+  + A DY+ GYTI  DI 
Sbjct: 120 TKAASSLTGDESTIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYIYGYTIINDI- 178

Query: 162 ATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQF 221
            TD +   +  Q  L K++   CP+GP+IVT DE+  P+N+N+   +N   +Q  NT+Q 
Sbjct: 179 -TDRKAQNEQDQAFLSKSLTGGCPMGPYIVTKDELPTPENVNIVTKVNNDIRQDGNTSQM 237

Query: 222 IHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETR 281
           I+KI D+I  +S  + L PGDII TGTP GVG    PP+FLQPGD +   I+NIGT  T 
Sbjct: 238 INKIDDLIEEISKYVALHPGDIIATGTPAGVGAGLQPPQFLQPGDEVKVTIDNIGTLTTY 297

Query: 282 V 282
           +
Sbjct: 298 I 298


>UniRef50_Q6N1I0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=13; Proteobacteria|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Rhodopseudomonas palustris
          Length = 280

 Score =  175 bits (427), Expect = 8e-43
 Identities = 85/211 (40%), Positives = 126/211 (59%), Gaps = 2/211 (0%)

Query: 66  LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125
           L +PV G  K + +GLNY DH  E  +  P  P +F K  +++ GPND ++ K   S  +
Sbjct: 63  LGSPVGGAPKFIAIGLNYADHAAEANMPIPAEPIVFMKAINSLCGPNDDVE-KPRGSTKL 121

Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185
             E+EL V+IG +A  V  + A +YV GY +  D+   +++  ++  Q   GK+ DTF P
Sbjct: 122 DWEVELAVIIGTRAKYVTEADALNYVAGYAVCNDVSERNFQL-ERAGQWTKGKSHDTFGP 180

Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
           +GPW+ T DEI +   L +   +NG ++Q  +T   I  +P I++ LS +MTL+PGDII 
Sbjct: 181 LGPWVATKDEIADVHKLGMWLDVNGQRRQTGSTATMIFNVPKIVSYLSELMTLMPGDIIT 240

Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
           TGTP GVG    PP++L  GDV+T  IE +G
Sbjct: 241 TGTPPGVGTGMKPPQYLNVGDVVTLGIEGLG 271


>UniRef50_A5MZU4 Cluster: Putative uncharacterized protein; n=1;
           Clostridium kluyveri DSM 555|Rep: Putative
           uncharacterized protein - Clostridium kluyveri DSM 555
          Length = 301

 Score =  175 bits (427), Expect = 8e-43
 Identities = 110/300 (36%), Positives = 157/300 (52%), Gaps = 22/300 (7%)

Query: 1   MKLLQFSYKNSDGIRA----GFLDGDNVV-DINKEDPKLPSTLIELLK------TNXXXX 49
           MK + + YK  + I        L+ +++  +I +E+P  P  ++EL+K       N    
Sbjct: 1   MKFVTYDYKGKENIGILKDKSILNFESIFYEIGEENP--PKDMVELIKYLDEDKLNEVEE 58

Query: 50  XXXXXXXXXXXLSGITLKAPV-HGNDKVLCVGLNYKDHCEEQKLTP------PELPFIFN 102
                      L  + LKAP+ +    V C+G NY++H  E KLT       P++P  F 
Sbjct: 59  FLKSKSLQGVFLDTVKLKAPIPYPKRNVFCLGKNYEEHAREIKLTRITGNEIPKVPIYFT 118

Query: 103 KFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGA 162
           K  S  +G  D+I+   +V+  V  E+EL VVIGK    +    A  Y+ GYTI  DI A
Sbjct: 119 KVASPAIGNGDSIEFSSEVTNQVDYEVELGVVIGKNGKNIKKEEAEKYIFGYTIINDISA 178

Query: 163 TDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFI 222
            D + +    Q   GK++DTFCP+GP IV  +EI  P NL++KC +N   +Q SNT   I
Sbjct: 179 RDLQGSH--IQWFKGKSLDTFCPMGPCIVHKNEIPFPINLDIKCWVNEELRQDSNTKNLI 236

Query: 223 HKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
             IP II+ LS  ++L  GDII TGTP GVG+  +P + L+ GD I   IE IG+    V
Sbjct: 237 FDIPYIISDLSKGVSLKAGDIIATGTPSGVGMGFSPIKVLKQGDSIECYIEKIGSLVNNV 296


>UniRef50_A1W846 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=2; Proteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Acidovorax sp. (strain JS42)
          Length = 281

 Score =  175 bits (425), Expect = 1e-42
 Identities = 97/278 (34%), Positives = 146/278 (52%), Gaps = 8/278 (2%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDNVV-DINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXX 59
           MKL++     ++  RAG +D   V+ D++   P +  T  +L                  
Sbjct: 1   MKLVRHGQPGAE--RAGLIDAQGVLRDLSMLLPDIGPT--QLAPRTLAALAAIDAARLPA 56

Query: 60  XLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM 119
            + G  L  PV G  K++CVGLNY DH  E  L  P  P +F K  S + GP D +++  
Sbjct: 57  VVPGTRLGCPVGGVGKIVCVGLNYADHAAEAGLPAPAEPVLFMKATSALSGPTDAVRIPP 116

Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179
              K    E+EL +VIG +  +V  + A  +V GY +A D+    ++  +   Q   GK 
Sbjct: 117 GALKTD-WEVELGIVIGTRMQQVAEADALAHVAGYVLANDVSERSYQMERG-GQWDKGKG 174

Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
            DTF P+GPW+VT+DEI +P  + +   +NG + Q  +T  FI  +P ++A +S  MTL 
Sbjct: 175 CDTFAPVGPWLVTTDEIPDPHAIGLWLEVNGQRMQDGHTRNFIFGVPRVLAYISQFMTLE 234

Query: 240 PGDIILTGTPGGVGVYRNP-PEFLQPGDVITSEIENIG 276
           PGD++LTGTP GVG+ + P P FL+ GDV+      +G
Sbjct: 235 PGDLVLTGTPAGVGLGQKPTPRFLRAGDVMRLGATGLG 272


>UniRef50_Q6I239 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=21; Firmicutes|Rep: Fumarylacetoacetate
           hydrolase family protein - Bacillus anthracis
          Length = 302

 Score =  174 bits (424), Expect = 2e-42
 Identities = 92/226 (40%), Positives = 131/226 (57%), Gaps = 5/226 (2%)

Query: 61  LSGITLKAPVHGNDK-VLCVGLNYKDHCEEQKLTP--PELPFIFNKFPSTVVGPNDTIKL 117
           L+ + + AP+    K +LCVG NY++H  E       PE   IF K P+TV+G ++ I  
Sbjct: 79  LTEVKILAPIPRPRKNILCVGKNYREHAIEMGGVESIPENIMIFTKAPTTVIGMDEKINS 138

Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177
               +  +  E EL +VIGK+  ++    A ++V GYTI  DI A D ++  K  Q  LG
Sbjct: 139 HPHATNELDYEGELAIVIGKRGKQIKKEKALEHVFGYTIINDITARDIQRKHK--QFFLG 196

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           K+ DTFCP+GP+++    I  P  L+++  +NG  +Q SNTN+ I  I +II+ +S  MT
Sbjct: 197 KSFDTFCPMGPYLIHKSMISTPNALHIETIVNGEVRQTSNTNKMIFSIEEIISTISKGMT 256

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           L PGDII TGTP GVG    PP+FL  GD +   +E IGT    V+
Sbjct: 257 LEPGDIIATGTPAGVGKGFTPPKFLHAGDEVVITVEGIGTLRNVVK 302


>UniRef50_A4SYK1 Cluster: Fumarylacetoacetate (FAA) hydrolase
           precursor; n=3; Proteobacteria|Rep: Fumarylacetoacetate
           (FAA) hydrolase precursor - Polynucleobacter sp.
           QLW-P1DMWA-1
          Length = 349

 Score =  174 bits (423), Expect = 2e-42
 Identities = 89/215 (41%), Positives = 123/215 (57%), Gaps = 9/215 (4%)

Query: 76  VLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 127
           + CVG NY DH EE             P++P +F K   T+ GP D I     +S  +  
Sbjct: 135 IYCVGWNYLDHFEEGLKHRADTAVKEYPKVPVLFTKGTQTMNGPFDNIPYDAGISTMIDW 194

Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187
           E EL VVIGKK   +   +A DYV GY+   D  A D ++ ++  Q   GK++D   P+G
Sbjct: 195 EAELAVVIGKKGKNISEENAMDYVFGYSAYNDTTARDIQQKRQSGQWFKGKSLDGHGPMG 254

Query: 188 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247
           PW+VT+  + N  +  + CS+NGV+KQ ++  Q   KIP IIA LS  +TLLPGDII TG
Sbjct: 255 PWVVTAGGV-NLDDTRIICSVNGVEKQNASYKQMYFKIPAIIAELSRGLTLLPGDIIATG 313

Query: 248 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           TP GVG  R P EF++PGD++ + I  IG    ++
Sbjct: 314 TPSGVGAGRTPQEFMKPGDMMETNITGIGILRNKI 348


>UniRef50_Q5LLB0 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=8; Proteobacteria|Rep: Fumarylacetoacetate
           hydrolase family protein - Silicibacter pomeroyi
          Length = 305

 Score =  173 bits (420), Expect = 6e-42
 Identities = 86/226 (38%), Positives = 138/226 (61%), Gaps = 10/226 (4%)

Query: 64  ITLKAPVHGNDK-VLCVGLNYKDHCEEQKLTP------PELPFIFNKFPSTVVGPNDTIK 116
           + L AP+    K +  +GLNY +H  E   +       P+ P +F+K P++V+   + I+
Sbjct: 78  VRLLAPIPRPRKNIFGIGLNYVEHVAESAKSLDTSKELPKEPVVFSKPPTSVIASGEGIQ 137

Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176
               +++ +  E+EL V+IGK+A+++   +A  +V GY++  D+ A D   N++  Q + 
Sbjct: 138 HNAAMTQQLDWEVELAVIIGKRATRIAKDNAMSHVFGYSVINDVSARD---NRRAGQWIF 194

Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236
            K  DTFCP GP I+T+D++ +P NL++  + NGV+KQ+SNT   +  IP +IA +S+ +
Sbjct: 195 SKGQDTFCPFGPAIITADDVPDPHNLDLWLTKNGVEKQRSNTRHLLFDIPTLIADISSGI 254

Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           TL PGDII TGTP GVG  R+P E++ PGDVI   ++ IG     V
Sbjct: 255 TLEPGDIIATGTPAGVGAGRDPQEWMWPGDVIECGVDGIGVLRNPV 300


>UniRef50_Q1GLV2 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=4; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Silicibacter sp. (strain TM1040)
          Length = 281

 Score =  172 bits (419), Expect = 7e-42
 Identities = 84/202 (41%), Positives = 121/202 (59%), Gaps = 2/202 (0%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K +C+GLNY DH  E  ++ PE P IF K  S + GPND +++    S     E+EL VV
Sbjct: 72  KFICIGLNYADHAAESGMSLPEEPVIFFKATSAICGPNDAVEIPR-TSVKTDWEVELGVV 130

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IGK A  +    A D+V GY +  D+   D++ ++   Q + GK+ DTF PIGPW+VT D
Sbjct: 131 IGKTAKYIGRDEALDHVAGYCVVNDLSERDFQLHRS-GQWVKGKSADTFGPIGPWLVTRD 189

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           E+ +PQNL +   +NG + Q  +T      +  +I+ LS  M+L PGD+I TGTP GVG+
Sbjct: 190 EVPDPQNLAMWLEVNGHRYQDGSTRTMHFDVATVISHLSQFMSLQPGDVISTGTPPGVGM 249

Query: 255 YRNPPEFLQPGDVITSEIENIG 276
            + P  +L+PGDV+   I  +G
Sbjct: 250 GQTPETYLKPGDVMELGIAGLG 271


>UniRef50_Q4J809 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4;
           Thermoprotei|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Sulfolobus acidocaldarius
          Length = 307

 Score =  172 bits (419), Expect = 7e-42
 Identities = 93/219 (42%), Positives = 129/219 (58%), Gaps = 6/219 (2%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128
           PV   +K+  + +NY+ H +E    PP+ P+IF KF +T++G N  + L    S  V  E
Sbjct: 90  PVTDPEKIFLLAVNYRAHGQETNNNPPKEPYIFTKFNNTLIGHNQPV-LFPRASNKVDYE 148

Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS---QLLLGKAMDTFCP 185
           IEL V++GK+A  V+SS A DYV GYTI  DI   D +   +I    + + GK +DT  P
Sbjct: 149 IELAVIMGKRAKYVNSSKALDYVFGYTIFNDISFRDKQFPPEIPYGMRWVHGKGLDTAAP 208

Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
           +GPWIVT DEI N  NL +K  +NG  +Q +     I K+  II  LSN +TL PGD+I 
Sbjct: 209 MGPWIVTKDEIDNINNLRLKLRVNGEIRQDAYAEDMIFKVEQIIEYLSNGITLKPGDVIS 268

Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           TGTP GV +     ++L+PGDV+ +EI  IG     + E
Sbjct: 269 TGTPSGVALATG--KYLKPGDVMEAEISKIGVLRNNLIE 305


>UniRef50_Q59050 Cluster: Uncharacterized protein MJ1656; n=4;
           Euryarchaeota|Rep: Uncharacterized protein MJ1656 -
           Methanococcus jannaschii
          Length = 237

 Score =  171 bits (417), Expect = 1e-41
 Identities = 92/210 (43%), Positives = 126/210 (60%), Gaps = 13/210 (6%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++CVGLNY DH +E  +  PE P IF K  S ++   D I ++  +SK V  E+EL +V
Sbjct: 39  KIICVGLNYIDHAKELNMEIPEYPIIFLKPTSAIIYNEDYI-IRPRISKRVDYEVELAIV 97

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IGKK   +    A DY++GYTI  D+ A D ++  K  Q    K+ DTFCPIGP IV   
Sbjct: 98  IGKKCKNIKKDEANDYIMGYTILNDVTARDLQQ--KDGQWTRAKSFDTFCPIGPRIVKDI 155

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           +   P NLN++C +NG  KQKSNT   I  + +++  ++++MTL PGDII TGTP GVG 
Sbjct: 156 D---PMNLNIECRVNGEIKQKSNTKNMIFDVYELVEFVASIMTLYPGDIISTGTPPGVGE 212

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRVEE 284
                  L+ GDV+  EIE IG     V++
Sbjct: 213 -------LKAGDVVECEIEGIGILRNYVKD 235


>UniRef50_Q1YHR9 Cluster: Putative fumarylacetoacetate hydrolase;
           n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
           fumarylacetoacetate hydrolase - Aurantimonas sp.
           SI85-9A1
          Length = 293

 Score =  171 bits (416), Expect = 2e-41
 Identities = 93/233 (39%), Positives = 134/233 (57%), Gaps = 12/233 (5%)

Query: 62  SGITLKAPVHGNDK-VLCVGLNYKDHCEE---------QKLTPPELPFIFNKFPSTVVGP 111
           S +T+ AP+    + + CVG NY++H  E          K   P  P IF K  S ++GP
Sbjct: 63  SEVTILAPLPETRRDIFCVGKNYREHASEFHNSGFDSGGKQAIPVAPVIFTKSLSAIIGP 122

Query: 112 NDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKI 171
             TI+  +D ++ V  E EL VVIGK+A  V  + A DYV GY +  D+  T  E  +  
Sbjct: 123 GATIEAGLDRTRTVDYEGELGVVIGKRAFGVTKADAMDYVFGYVVINDV--TSRELQRHH 180

Query: 172 SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIAR 231
           SQ ++GK +DTF P+GP +VT+DE+ +   L V  ++NG  +QK++    I  IP +I  
Sbjct: 181 SQWVIGKGIDTFAPMGPVLVTADEVPDVTKLTVTTTVNGETRQKASVAGLIFDIPTLIET 240

Query: 232 LSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           ++  MTLLPGDII TGTP GVG+  +PP +L  GD +   I+ +GT E  V +
Sbjct: 241 MTATMTLLPGDIIATGTPAGVGIGFDPPRYLADGDRVAVTIDGLGTLENPVRQ 293


>UniRef50_Q6L066 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Picrophilus torridus|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Picrophilus torridus
          Length = 281

 Score =  170 bits (414), Expect = 3e-41
 Identities = 95/222 (42%), Positives = 132/222 (59%), Gaps = 7/222 (3%)

Query: 62  SGITLKAPVHGN-DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKLKM 119
           +GI    P   N +K++CVG NYK+H  E     PE P +F+KF +T+ G  ND I   +
Sbjct: 59  TGIDKYGPAISNPEKIICVGKNYKEHALETGSGIPESPVLFSKFNNTLTGHLNDII---I 115

Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179
           D S ++  E EL +VIGKKA  VD + A DYV GY IA D+ A D +   + SQ LLGK 
Sbjct: 116 DFSDSIDYEGELGIVIGKKARNVDENDAMDYVFGYYIANDVSARDLQY--RTSQWLLGKT 173

Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
            D F P GP+IVT DE+ +P NL+++   NG   Q SNT   I  I  +I  +S  +TL+
Sbjct: 174 PDGFYPNGPFIVTKDEVNDPMNLDIRTLRNGDTVQHSNTRNMIFDIKYLIGYISKYLTLM 233

Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETR 281
           PGD+I TGTP GV +  N   +++  + I  +IE +G+ + R
Sbjct: 234 PGDVISTGTPEGVILGTNEKNWIKNNETIEVKIEKLGSLKNR 275


>UniRef50_A5AB73 Cluster: Function: E. coli hpaG is a bifunctional
           decarboxylase/isomerase; n=4; Pezizomycotina|Rep:
           Function: E. coli hpaG is a bifunctional
           decarboxylase/isomerase - Aspergillus niger
          Length = 358

 Score =  169 bits (412), Expect = 5e-41
 Identities = 93/221 (42%), Positives = 128/221 (57%), Gaps = 6/221 (2%)

Query: 66  LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125
           L  PV     V+C+GLNYK H +E  L  P  P +F K    + GP +TI +  D    +
Sbjct: 54  LLPPVPNTPLVICIGLNYKQHAKEASLDVPTYPPVFTKPADVLAGPFETIPIHRDAQSHL 113

Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKI-SQLLLGKAMDTFC 184
             E ELTVVIGK A  V +  A DYVLGYT   D+ A +++  +    Q    K+ D F 
Sbjct: 114 DYEGELTVVIGKDAKNVSAEDALDYVLGYTAGNDLSARNFQMPEASGGQFCYAKSFDKFA 173

Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244
           PIG  +V++ E+ +PQ L++   +NGV KQ +NT+  I  + DI++ LS  MTL  G +I
Sbjct: 174 PIGHVLVSAQEVQDPQQLSLVTKVNGVVKQTTNTSDMIWGVRDIVSHLSRGMTLRKGTLI 233

Query: 245 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285
           +TGTP GVG +R   EFLQ GDV+  E+E +G  E  V +F
Sbjct: 234 MTGTPSGVGFFRK--EFLQDGDVV--EVE-LGVREPGVIDF 269


>UniRef50_A7DRD3 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Candidatus Nitrosopumilus
           maritimus SCM1|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Candidatus Nitrosopumilus maritimus
           SCM1
          Length = 289

 Score =  169 bits (412), Expect = 5e-41
 Identities = 90/223 (40%), Positives = 126/223 (56%), Gaps = 3/223 (1%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           LS   L AP+   +K++C+  NY DH +EQ LT PE P I  K  + + G N  I+   D
Sbjct: 65  LSKFKLLAPIPNPNKIICLAFNYVDHAKEQGLTAPEDPAIVIKPRTALNGNNANIECP-D 123

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
               +  E+EL ++IGK    +    A + V GY +  D+ A D +   K  Q   GK+ 
Sbjct: 124 FVTQLDYEVELALIIGKNCKNISVEEAQNVVFGYMVFNDVSARDIQFKDK--QFTRGKSF 181

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           D+F P GPWI T+DEI  PQNL +   ING  +Q S+T+    KIP+II+++S VMTL  
Sbjct: 182 DSFAPCGPWITTADEIQEPQNLKLTTKINGELRQNSSTSNMFIKIPEIISKISKVMTLEK 241

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           GDII TGTP GV + +    FL+ GD +  EIE +G     ++
Sbjct: 242 GDIISTGTPAGVMLNKPNAIFLKDGDKVEMEIEGLGVLNNTIK 284


>UniRef50_Q89JJ8 Cluster: Blr5285 protein; n=7; Proteobacteria|Rep:
           Blr5285 protein - Bradyrhizobium japonicum
          Length = 283

 Score =  169 bits (411), Expect = 7e-41
 Identities = 98/284 (34%), Positives = 146/284 (51%), Gaps = 8/284 (2%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXX-- 58
           MKLL F   +      G +  + VVD+        +TL +LL+                 
Sbjct: 1   MKLLSFIVDSRTSF--GAVKDNGVVDLGARMAGC-TTLRQLLEAGRVAEAAKLVASAAPD 57

Query: 59  XXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLK 118
             L  ++    +    K++CVGLNY+DH  E      E P +F +FP + VG    I +K
Sbjct: 58  HALDKVSFAPVIPDPGKIICVGLNYRDHVAETGRIVTEKPALFVRFPCSQVGHLQPI-VK 116

Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGK 178
             VS     E EL +VIGK+   + ++ A D++ GY+   +    DW+++   SQ L GK
Sbjct: 117 PKVSDDFDYEGELALVIGKEGRHIPANRALDHIAGYSCYNEGSVRDWQRHT--SQFLSGK 174

Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTL 238
                   GPW+VT+DEI +P  L ++  +NG   Q + T+  I  IP +IA +S +  L
Sbjct: 175 TFAESGSFGPWLVTADEIPDPSKLTLQTRLNGTVVQDTTTDLLITAIPGLIAYISTICPL 234

Query: 239 LPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           +PGD+I+TGTPGGVG  R PP +++PGD +  EI  IGT   +V
Sbjct: 235 VPGDVIVTGTPGGVGAKRTPPLWMRPGDTVEVEISGIGTLRNKV 278


>UniRef50_A4V8P0 Cluster: Putative fumarylacetoacetate hydrolase
           family protein; n=2; Arthrobacter|Rep: Putative
           fumarylacetoacetate hydrolase family protein -
           Arthrobacter nitroguajacolicus
          Length = 299

 Score =  169 bits (411), Expect = 7e-41
 Identities = 89/208 (42%), Positives = 122/208 (58%), Gaps = 6/208 (2%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           KV+C GLNY DH +E     P+ P +F K+  T+VG +D I +    S  V  E EL VV
Sbjct: 75  KVICCGLNYGDHIQEMGRALPDYPTLFAKYADTLVGASDPIYVHG--SDKVDWEAELAVV 132

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IG    +VD   A   + GYT+A D+   DW+ N+ + Q   GKA D   P+GP ++T+D
Sbjct: 133 IGSNLYRVDEDQALAGIAGYTVANDVSMRDWQ-NRTL-QWFQGKAFDATTPLGPVMLTAD 190

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           E   P + +V   +NG Q QK NT+  +     ++A +S    L PGD++LTGTPGGVG+
Sbjct: 191 EA--PADFDVYGYVNGEQVQKGNTSTLVFGPARLVAYISQFTMLRPGDVVLTGTPGGVGM 248

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282
             NPP FL  GDV+T+EI  IG  E R+
Sbjct: 249 GMNPPRFLSDGDVLTTEIPGIGRLENRI 276


>UniRef50_A1RQJ1 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=5; Thermoprotei|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Pyrobaculum islandicum (strain DSM 4184 / JCM 9189)
          Length = 310

 Score =  169 bits (411), Expect = 7e-41
 Identities = 86/227 (37%), Positives = 132/227 (58%), Gaps = 9/227 (3%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           I  + PV   +K+LCV +NY++H  E  + PP+ P+ F KFP+ +VG    + +K  V +
Sbjct: 86  IKWEPPVPNPEKILCVAVNYREHGAETGIEPPDKPYFFPKFPNALVGHEGYV-VKHRVVQ 144

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK--NKKISQL----LLG 177
            +  E+EL VV+G+    ++   A DYV GYT+  D+   DW+    K   Q     + G
Sbjct: 145 KLDWEVELVVVMGRPGKYIEPERALDYVFGYTVGLDMSMRDWQNPDEKTARQYGKNWIWG 204

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           K MDT  P+GP+I T DE+ +P  L ++  +NG  +Q+ NT+Q I  I  +I   S  +T
Sbjct: 205 KTMDTAAPVGPYIATRDEVPDPNRLGLRLWVNGQLEQEGNTSQLIFNIQQLIYWASQGIT 264

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           L PGD+I TGTP GVG  +   +FL+ GD++ +E+E+IG     + E
Sbjct: 265 LRPGDLIFTGTPPGVGWAKG--KFLKGGDIVEAEVESIGRLRAYIIE 309


>UniRef50_O27551 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=4; Archaea|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Methanobacterium thermoautotrophicum
          Length = 260

 Score =  168 bits (409), Expect = 1e-40
 Identities = 90/223 (40%), Positives = 133/223 (59%), Gaps = 14/223 (6%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L  + +  PV  + KV+CVGLNY+DH  E  +  P+ P IF K P+TV+G  DT+ +  +
Sbjct: 46  LDDVRILPPVSPS-KVVCVGLNYRDHAAELGMDIPDEPIIFLKPPTTVIGSGDTV-IYPE 103

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           +S  V  E+EL  V+ ++A +VDSS A +++ GYT+  D+ A D ++     Q    K+ 
Sbjct: 104 MSSEVDYEVELAAVVSERARRVDSSAASEFIAGYTVLNDVTARDLQRRD--GQWTRAKSF 161

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           DTFCPIGP I T      P NL++   +NG  +Q SNT+  I  + +++  +S+VMTL P
Sbjct: 162 DTFCPIGPVIETDV---TPDNLDISLKLNGEVRQSSNTSNMIFTVHELLEFISHVMTLEP 218

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           GD+I TGTP GVG        + PGD + + +E +GT   RVE
Sbjct: 219 GDVIATGTPPGVGQ-------MVPGDTVRATVEGVGTLVNRVE 254


>UniRef50_A7IDT5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Proteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Xanthobacter sp. (strain Py2)
          Length = 281

 Score =  167 bits (407), Expect = 2e-40
 Identities = 90/282 (31%), Positives = 139/282 (49%), Gaps = 6/282 (2%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX 60
           MK   F++    G   G +    ++D+ +  P+ P TL   +                  
Sbjct: 1   MKFASFTHAGRAGY--GLVTDGGIIDLTRRFPEAP-TLRTFIAGGLDRAAAVAGAPADFA 57

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           LS +TL   +   DK++CVGLNY DH  E   T    P +F ++  + VG    +   ++
Sbjct: 58  LSEVTLAPVIPDPDKIVCVGLNYHDHVNETGRTVTPNPMLFARYAGSQVGAGTALVKPLE 117

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
            S     E EL V+IGK   ++  + A  +V GY    D    DW+++   SQ + GK  
Sbjct: 118 -SDEFDYEGELAVIIGKAGRRISEADALSHVAGYACYNDASVRDWQRHT--SQFMPGKTF 174

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
                 GPW+V++DEI +P  L +   +NG Q Q ++ +  I  IP +IA  S ++ LLP
Sbjct: 175 AATGAFGPWMVSADEIPDPTRLTLATRLNGAQVQHTSVDLMITPIPTLIAYTSTILPLLP 234

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GD+I++GTPGGVG  R P  F++ GDV+  E+  IG     +
Sbjct: 235 GDVIVSGTPGGVGARRTPKLFMKDGDVVEVEVSGIGVLRNPI 276


>UniRef50_A6TL34 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Alkaliphilus metalliredigens
           QYMF|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Alkaliphilus metalliredigens QYMF
          Length = 298

 Score =  167 bits (406), Expect = 3e-40
 Identities = 82/207 (39%), Positives = 121/207 (58%), Gaps = 8/207 (3%)

Query: 76  VLCVGLNYKDHCEEQK------LTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 129
           V+C+GLNYK H  E +      +  PE P  F K  +  +GP + I     +++ V  E+
Sbjct: 87  VICLGLNYKAHVAESQSALSAGIKMPEFPVYFTKMSTQAIGPQEAINSHPQITQEVDYEV 146

Query: 130 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 189
           EL V+IGK  + +      D++ GYTI  D+ A D ++    +Q + GK++DTF  +GPW
Sbjct: 147 ELAVIIGKGGTNIPPEEVQDHIFGYTILNDVSARDLQRRH--NQWVKGKSLDTFTVMGPW 204

Query: 190 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 249
           I+  + I  P  L++   +NG  +Q SNT  FI  IP +I+ LS  +TL  GD+I TGTP
Sbjct: 205 IMEKETISLPVELDLYSKVNGEIRQHSNTKDFIFDIPTVISELSKGLTLEAGDVIATGTP 264

Query: 250 GGVGVYRNPPEFLQPGDVITSEIENIG 276
            GVG+  NPP++L+ GDV+   IE IG
Sbjct: 265 AGVGMGFNPPKYLKAGDVVECYIEKIG 291


>UniRef50_Q12CU6 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=2; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 287

 Score =  167 bits (405), Expect = 4e-40
 Identities = 90/230 (39%), Positives = 124/230 (53%), Gaps = 12/230 (5%)

Query: 61  LSGITLKAPVH-GNDKVLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGP 111
           L  + L+AP+      + CVG NY  H +E            P   P +F K P  VVGP
Sbjct: 59  LHDVKLEAPIPLPRRNIFCVGRNYHAHAKELSASVFKDNSANPASWPIVFTKVPECVVGP 118

Query: 112 NDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKI 171
            D + L   VS+ +  E EL +VIG     +  + A  +V GYTI  D+ A D +   + 
Sbjct: 119 TDDVMLPTGVSEEIDYESELAIVIGTGGRNISRAAAMQHVFGYTIINDVTARDVQMRHQ- 177

Query: 172 SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIAR 231
            Q  LGK+ DTFCP+GPWIVT+DE+   +   V+  +NG  +Q + T   I  IP +I  
Sbjct: 178 -QWDLGKSFDTFCPMGPWIVTADELDGSRT-RVRGWVNGELRQDAQTTDLIFDIPALIET 235

Query: 232 LSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETR 281
            S  +TL PGD+I TGT  GVG+   PP++L+ GDV+  EI+ IG  E R
Sbjct: 236 CSRGITLYPGDVIATGTAAGVGMGMKPPQYLKAGDVVRIEIDGIGAIENR 285


>UniRef50_A4SYH8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Polynucleobacter sp.
           QLW-P1DMWA-1|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 299

 Score =  167 bits (405), Expect = 4e-40
 Identities = 97/284 (34%), Positives = 146/284 (51%), Gaps = 14/284 (4%)

Query: 7   SYKNSDGIRA-GFLDGDNVVDINKEDPKL----PSTLIELLKT------NXXXXXXXXXX 55
           S  N+DG    G +    V+D+     K+    P TL +LL+       N          
Sbjct: 9   SIMNADGTETLGVVTPKGVIDVRAVAKKMKIAAPVTLDQLLQEGNAQGFNKVVASADQSG 68

Query: 56  XXXXXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTI 115
                 S IT         K++CVGLNY+ H +E  +  P +P +FNK+ +++   N  +
Sbjct: 69  VPYLQESNITFGRLFKSPGKIVCVGLNYRAHADEVGMVHPRVPPLFNKYNNSLAAHNCLL 128

Query: 116 KLKM-DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174
           ++    VS  +  E EL +VIGK+   V  S A DYV GY  + D  + D +      Q 
Sbjct: 129 QIPPPSVSYKLDYETELLIVIGKQMRNVPESAALDYVAGYCTSNDFSSRDLQLELPSGQW 188

Query: 175 LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSN 234
           ++GK +D + PIGP+ VT D +GNP NL VK  +NG  +Q SNT+ FIH    +++ +S 
Sbjct: 189 MIGKTLDQYAPIGPYFVTGDLVGNPNNLQVKTWVNGELRQNSNTSDFIHNTQKMLSYIST 248

Query: 235 VMTLLPGDIILTGTPGGV--GVYRNPPEFLQPGDVITSEIENIG 276
              L PGDI+ TGTP GV  G+ ++   +L+ GD + S +E +G
Sbjct: 249 YWALEPGDIVFTGTPQGVIAGMPKDKQVWLKKGDKVVSSVEKLG 292


>UniRef50_Q1VM36 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase;
           n=1; Psychroflexus torquis ATCC 700755|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic
           acid hydratase - Psychroflexus torquis ATCC 700755
          Length = 251

 Score =  166 bits (404), Expect = 5e-40
 Identities = 85/190 (44%), Positives = 116/190 (61%), Gaps = 2/190 (1%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           I L +P+    K++CVGLNY  H +E  +  P  P +F K  S +VGP D I L     K
Sbjct: 64  IRLGSPIDRPSKIVCVGLNYAKHAKESGMEVPTEPVLFFKASSAIVGPYDDIILPKKSEK 123

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183
           +   E+EL ++IG KAS V  S A D+V GY I  DI   +++  +   Q + GK+ DTF
Sbjct: 124 SD-WEVELAIIIGDKASYVKESEAMDHVAGYVIHNDISEREYQLERS-GQWVKGKSCDTF 181

Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243
            PIGP++VT+DEI +P NL +   +NG   Q SNT+  I  IP +++ +S  MTLLPGD+
Sbjct: 182 APIGPFMVTTDEIDDPHNLRLWLKLNGETMQDSNTSDLIFGIPKLVSYISTYMTLLPGDV 241

Query: 244 ILTGTPGGVG 253
           I TGTP GVG
Sbjct: 242 ISTGTPFGVG 251


>UniRef50_Q0S8P7 Cluster: Probable hydrolase; n=1; Rhodococcus sp.
           RHA1|Rep: Probable hydrolase - Rhodococcus sp. (strain
           RHA1)
          Length = 553

 Score =  166 bits (404), Expect = 5e-40
 Identities = 89/232 (38%), Positives = 132/232 (56%), Gaps = 15/232 (6%)

Query: 63  GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP------------PELPFIFNKFPSTVVG 110
           G  L AP+  +  V CVG NY +H  E   +             P+ P +F K  +TV+ 
Sbjct: 60  GGKLLAPITPHRNVFCVGRNYSEHAAEFAESGFDATGSADGQHVPQYPVVFTKPAATVIA 119

Query: 111 PNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK 170
             D +    D++ A+  E E+ ++IGK+ASKV    A DYV GYT+  D+ A D +++ K
Sbjct: 120 CGDPVDPHTDITSALDYEGEIGIIIGKRASKVSRDDAMDYVWGYTLINDVTARDLQRDHK 179

Query: 171 ISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIA 230
             Q  +GK++DTFCP+GPW VT+DEI +  +L ++  +NG  +Q +NT Q I  +P II 
Sbjct: 180 --QWFIGKSLDTFCPLGPWAVTADEI-DINDLQLQTRVNGELRQDTNTAQLIFDVPTIIE 236

Query: 231 RLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
            LS  +TL PGD+I TGTP GVG+  +PP++L  GD +      +G     +
Sbjct: 237 TLSAGITLEPGDVIATGTPVGVGIGFDPPKYLVEGDEVIVSAPGLGELRNTI 288


>UniRef50_Q9VU50 Cluster: CG11251-PA; n=1; Drosophila
           melanogaster|Rep: CG11251-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 338

 Score =  166 bits (403), Expect = 6e-40
 Identities = 89/219 (40%), Positives = 126/219 (57%), Gaps = 7/219 (3%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           + L  P+    K++ V  NY D+C+EQ ++ P  P    KF S++ G  D I+     +K
Sbjct: 122 LRLLPPIDSPSKIIGVDCNYVDNCDEQHISIPREPSFHVKFASSITGALDNIRAHSS-AK 180

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183
            +    +L VV+GK+  +V    A ++V G+ + QDI A DW         L G +MDTF
Sbjct: 181 HIDYGCQLAVVMGKRCREVSPKEALNHVFGFMVVQDIVARDWNVP------LGGHSMDTF 234

Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243
            P+GP IV    + +  NL +K  ING ++Q  NT   I KI  +I RLS  +TL PGDI
Sbjct: 235 LPLGPTIVHRCHVPDLNNLWIKTIINGEERQTGNTRNMIFKIDFLIHRLSQYLTLCPGDI 294

Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           ILTGTP G G +R+P  FL+PGD+I SEI+N+G    +V
Sbjct: 295 ILTGTPAGSGAFRHPSCFLKPGDLIESEIQNLGKMCNKV 333


>UniRef50_Q0RCN1 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase (HHDD isomerase)/5-
           carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate decarboxylase;
           n=1; Frankia alni ACN14a|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD
           isomerase)/5- carboxymethyl-2-oxo-hex-3-ene-1, 7-dioate
           decarboxylase - Frankia alni (strain ACN14a)
          Length = 276

 Score =  165 bits (402), Expect = 9e-40
 Identities = 87/222 (39%), Positives = 125/222 (56%), Gaps = 3/222 (1%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L G  L   V    K++C+GLNY  H +E   TPP  P +F K+   ++GP D I L   
Sbjct: 55  LDGADLAPLVPAPPKIICMGLNYATHLKEMGRTPPTHPTLFAKYTRALIGPTDDI-LVPP 113

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           V++AV  E EL  VIG      D + A + + GYTI  D+   DW+   +  Q L GK+ 
Sbjct: 114 VTEAVDWEGELAFVIGTTVRFADEAAAREAIAGYTIMNDVTMRDWQF--RTLQFLQGKSF 171

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           +   P+GP +VT DE+ NP +L ++  +NG   QKS T+  +    +I+  +S  +TL P
Sbjct: 172 EGSTPLGPALVTPDELDNPADLALRTLVNGEVMQKSRTSDLLFPPVEIVRYVSQFITLEP 231

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GD++ TGTPGGVG  RNP  +L  GDV+T ++E +G     V
Sbjct: 232 GDVLTTGTPGGVGHGRNPKVYLADGDVVTVDVEGLGVVRNTV 273


>UniRef50_O53242 Cluster: POSSIBLE
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE; n=41;
           Bacteria|Rep: POSSIBLE
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE -
           Mycobacterium tuberculosis
          Length = 239

 Score =  165 bits (401), Expect = 1e-39
 Identities = 93/222 (41%), Positives = 128/222 (57%), Gaps = 11/222 (4%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L+ + L AP+  + KV+CVG NY DH  E    PP  P IF K  + ++GPN  I+L  +
Sbjct: 23  LADVRLLAPILAS-KVVCVGKNYADHIAEMGGRPPADPVIFLKPNTAIIGPNTPIRLPAN 81

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
            S  V  E EL +VIG+    V ++ A D +LGYTI  D+ A D +++    Q    K  
Sbjct: 82  ASP-VHFEGELAIVIGRACKDVPAAQAVDNILGYTIGNDVSARDQQQSD--GQWTRAKGH 138

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           DTFCP+GPWIVT     +P +L ++  +NG  KQ + T+  IH I  I+  +S +MTLLP
Sbjct: 139 DTFCPVGPWIVTDLAPFDPADLELRTVVNGDVKQHARTSLMIHDIGAIVEWISAIMTLLP 198

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GD+ILTGTP GVG        ++ GD ++  IE IGT    V
Sbjct: 199 GDLILTGTPAGVGP-------IEDGDTVSITIEGIGTLTNPV 233


>UniRef50_Q0SJB3 Cluster: Possible fumarylacetoacetate hydrolase;
           n=2; Rhodococcus|Rep: Possible fumarylacetoacetate
           hydrolase - Rhodococcus sp. (strain RHA1)
          Length = 296

 Score =  165 bits (401), Expect = 1e-39
 Identities = 83/212 (39%), Positives = 120/212 (56%), Gaps = 4/212 (1%)

Query: 66  LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125
           L APV    ++  +G+NY DH EE  LT P+ PF+F KFP+++ GP DTI+        V
Sbjct: 63  LGAPVPRPGQIFAIGVNYADHVEESGLTLPDAPFVFTKFPASITGPYDTIE---HPGGLV 119

Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLLLGKAMDTFC 184
             E+EL  VIGK+A  V  +  ++YV G T+ QD+   D +       Q  LGK+   F 
Sbjct: 120 DFEVELVAVIGKEARHVPVAEGWEYVAGLTLGQDLSERDLQLSGPPPQQFTLGKSFAGFA 179

Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244
           PIGP +VT DE  +P ++ V   ++G   Q S T   I  IP +++ LS+++ L PGD+I
Sbjct: 180 PIGPVLVTPDEFADPDDIEVSTILSGELMQNSRTRHLIFPIPVLVSYLSSILPLRPGDLI 239

Query: 245 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
            TGTP G+G  R+P   +   D + S  + IG
Sbjct: 240 FTGTPSGIGFTRDPKRLIGVDDELVSRADTIG 271


>UniRef50_Q0B7L5 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=6; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Burkholderia cepacia (strain ATCC 53795 / AMMD)
          Length = 291

 Score =  165 bits (401), Expect = 1e-39
 Identities = 96/291 (32%), Positives = 150/291 (51%), Gaps = 12/291 (4%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX 60
           MKL+ F  +N D  R G LDG +V+D+N+ DP +P+ L   L+                 
Sbjct: 1   MKLITFK-QNGD-TRLGVLDGSDVIDLNRADPAVPADLRAALEAGVDVVAAARNAATRAD 58

Query: 61  ------LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT 114
                 LS + L   V    K++C+G N+ DH +E     P  P IF +  ++++   D 
Sbjct: 59  VGNRIPLSEVELAPVVPKPGKIVCLGHNFYDHAKEGGNLKPVYPLIFFRGATSLIAHGDP 118

Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174
           + ++  VS+ +  E EL VVIGK    V   +A D+V GY    D+   D++K  + +Q 
Sbjct: 119 V-IRPFVSEKLDYEAELVVVIGKTGRHVKRENALDHVFGYACFNDVSVRDYQK--RTAQW 175

Query: 175 LLGKAMDTFCPIGPWIVTSDEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233
            +GK  D     GPW+VTSDE+      L ++  +NG   Q++NT   I  + + I  L+
Sbjct: 176 TIGKNFDGTGAFGPWLVTSDELPPGAAGLKLELRLNGEAMQRANTADMIWSVAETIELLT 235

Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
             +TL PGD+++ GTP GVG  R PP +++ GD +  +IE IG     V++
Sbjct: 236 ECLTLEPGDVVVMGTPAGVGFARTPPVWMKAGDRVEVDIEGIGVLSNVVQD 286


>UniRef50_A4FCY5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Saccharopolyspora erythraea NRRL
           2338|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Saccharopolyspora erythraea (strain
           NRRL 23338)
          Length = 233

 Score =  164 bits (399), Expect = 2e-39
 Identities = 86/198 (43%), Positives = 116/198 (58%), Gaps = 2/198 (1%)

Query: 79  VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 138
           V LNY D   E     P +PF+F K  S+V+G  D I +   V++ V  E EL VVIG +
Sbjct: 19  VALNYVDSIAEMGFERPTVPFLFPKLSSSVIGDGDPIVVDTTVTRFVDWETELAVVIGTE 78

Query: 139 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 198
           A  V ++ A + V GYT+A DI A D        Q L GK +DTFCP+G  +V + EI +
Sbjct: 79  ARNVPAAEALEVVYGYTVANDISARDLLTAD--GQWLRGKGLDTFCPLGHVVVPAAEIPD 136

Query: 199 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 258
           PQ L V+  +NG   Q   T   +  + ++I+ LS   TL PGD+ILTGTP G G + +P
Sbjct: 137 PQALAVRTWLNGEIVQDGTTADMVFGVGELISYLSRFFTLRPGDVILTGTPAGCGAFMDP 196

Query: 259 PEFLQPGDVITSEIENIG 276
           P  L+PGDV+ SE+E IG
Sbjct: 197 PRGLRPGDVVESEVEGIG 214


>UniRef50_O58377 Cluster: Uncharacterized protein PH0643; n=4;
           Thermococcaceae|Rep: Uncharacterized protein PH0643 -
           Pyrococcus horikoshii
          Length = 230

 Score =  164 bits (399), Expect = 2e-39
 Identities = 94/207 (45%), Positives = 123/207 (59%), Gaps = 11/207 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++ +  NY +H  E    PPE P IF K PS ++GP  +I L    SK V  E+EL V+
Sbjct: 22  KIVALAKNYAEHAREMGSEPPEEPIIFLKPPSALIGPGSSIILPRR-SKRVDHEVELAVI 80

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 192
           +GK+A  V +S AFDY+LGYTI  DI A D   E  KK     + K  DTF PIGP +V 
Sbjct: 81  MGKRAKNVPASKAFDYILGYTIILDITARDLQAEARKKGYPWTISKGFDTFAPIGPRVVD 140

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252
           S E+ +P +L +   +NG  +Q   T+Q I KIP++I  +S++MTL PGDII TGTP GV
Sbjct: 141 SREL-DPSDLEIGLKVNGKIRQLGRTSQMIFKIPELIEYISHIMTLEPGDIIATGTPPGV 199

Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFE 279
           G  R+       GD I + IE IG  E
Sbjct: 200 GPLRH-------GDRIEAWIEGIGKME 219


>UniRef50_Q89GI5 Cluster: Bll6360 protein; n=157; Bacteria|Rep:
           Bll6360 protein - Bradyrhizobium japonicum
          Length = 314

 Score =  164 bits (398), Expect = 3e-39
 Identities = 83/210 (39%), Positives = 122/210 (58%), Gaps = 3/210 (1%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128
           PV G  K + +GLNY DH  E  L  P  P +F K  +++ GPND + L     K    E
Sbjct: 92  PVSGVGKFVAIGLNYADHAAEAGLPLPSEPIVFQKAITSLSGPNDAVVLPRGSLKGD-WE 150

Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188
           +EL +VIG +AS V+   A  YV GY +  D+   +++  +       GK  DTF P+GP
Sbjct: 151 VELGIVIGSRASYVEPVEALQYVAGYCVVNDVSEREYQMERG-GTWDKGKGCDTFGPVGP 209

Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248
           W+VT+DE+ +P  L++   +NG + Q+ NT   +     I++ +S  MTL+PGDII TGT
Sbjct: 210 WLVTTDEVPDPGRLDIWLELNGRRMQQGNTRTMVFGCAGIVSYVSQFMTLMPGDIIATGT 269

Query: 249 PGGVGVYRNP-PEFLQPGDVITSEIENIGT 277
           P GVG+   P P +L+ GD++T  I+ +GT
Sbjct: 270 PPGVGMGMKPDPIYLKVGDIMTLGIQGLGT 299


>UniRef50_A1DM45 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=5; Pezizomycotina|Rep: Fumarylacetoacetate
           hydrolase family protein - Neosartorya fischeri (strain
           ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
           fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
          Length = 289

 Score =  162 bits (394), Expect = 8e-39
 Identities = 86/221 (38%), Positives = 122/221 (55%), Gaps = 4/221 (1%)

Query: 66  LKAPVHGND--KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM--DV 121
           L AP+   D   V C+GLNY+ H  E  L  P+ P +F K  +++ GP D I +      
Sbjct: 60  LLAPLARKDIRTVRCLGLNYEQHARESNLPIPKYPVLFYKPVTSIAGPRDDIPISTMAQE 119

Query: 122 SKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMD 181
            + +  E EL +VIGK+A  V  S A DYVLGY +  D+   DW+  +   Q  LGK  D
Sbjct: 120 GEGLDYECELVIVIGKEAKDVPESRALDYVLGYAVGNDVSHRDWQIKRGGGQWGLGKGFD 179

Query: 182 TFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241
            + P GP IV+S  I +P  L++   +NG   Q S+T   I  +  ++A LS   TLLPG
Sbjct: 180 GWAPFGPGIVSSRLIRDPNALHISTRLNGQVVQSSSTKDMIFSVAKVVAFLSQGTTLLPG 239

Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           D+I TGTP GVG+ R P  +L+ GD +   +E +G+   +V
Sbjct: 240 DLIFTGTPQGVGMGRKPALWLKDGDQVEVSLEGVGSCVNQV 280


>UniRef50_Q2UMF8 Cluster: Predicted fumarylacetoacetate hydralase;
           n=8; Pezizomycotina|Rep: Predicted fumarylacetoacetate
           hydralase - Aspergillus oryzae
          Length = 289

 Score =  162 bits (393), Expect = 1e-38
 Identities = 88/222 (39%), Positives = 121/222 (54%), Gaps = 6/222 (2%)

Query: 66  LKAPVHGND--KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTI---KLKMD 120
           L AP+   D   V C+GLNY+ H  E  L  P+ P +F K  + + GP D I    +  D
Sbjct: 60  LLAPLAREDIATVRCLGLNYEQHARESNLPIPKYPVLFYKPITAITGPYDDIPICSMAQD 119

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           V + +  E EL +VIGK+A  +    A DYVLGY +  DI   DW+  +   Q  LGK  
Sbjct: 120 V-EGLDYECELVLVIGKQAKNIPEEQALDYVLGYAVGNDISHRDWQLKRGGGQWGLGKGF 178

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           D + P GP IV++  I NP  LN+   +NG   Q S+T   I  +   ++ LS   TLLP
Sbjct: 179 DGWAPFGPGIVSTKLIRNPNALNISTKVNGQTVQSSSTKDMIFGVAQTVSFLSQGTTLLP 238

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GD+I TGTP GVG+ R P  +L  GD +   +E++G+   RV
Sbjct: 239 GDLIFTGTPQGVGMGRKPAAWLTNGDQVEVSLEDVGSCVNRV 280


>UniRef50_Q7WM74 Cluster: Putative hydrolase; n=3;
           Burkholderiales|Rep: Putative hydrolase - Bordetella
           bronchiseptica (Alcaligenes bronchisepticus)
          Length = 304

 Score =  161 bits (392), Expect = 1e-38
 Identities = 86/229 (37%), Positives = 125/229 (54%), Gaps = 9/229 (3%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP-------PELPFIFNKFPSTVVGPND 113
           L  + +  P+     V CVG NY++H  E  L         PE    F K P+ V+G   
Sbjct: 76  LQAVRVLPPLPMARNVFCVGRNYREHIIEGNLARGRPANSFPEAIEFFTKAPTAVIGHGG 135

Query: 114 TIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ 173
            +K    ++ ++  E+EL +VIG+  + +    A D+V GYTI  DI A D +      Q
Sbjct: 136 HVKRHAGLTDSLDYEVELAIVIGRAGADIPREKALDHVFGYTIVNDITARDLQARH--GQ 193

Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233
              GK++DT CP+GP +V    I +  NL V  S+NG  +Q+ NT+  I  +  ++A+LS
Sbjct: 194 WFKGKSLDTSCPMGPVVVHRSAIPDANNLAVSLSVNGELRQQDNTSDMIFDVAAVVAQLS 253

Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
             MTLLPGD+I TGTP GVG    PP  LQ GDV+++ +E+IGT    +
Sbjct: 254 AGMTLLPGDVIATGTPKGVGFALTPPRCLQVGDVVSASVEHIGTLTNEI 302


>UniRef50_Q0V440 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 286

 Score =  161 bits (392), Expect = 1e-38
 Identities = 81/210 (38%), Positives = 120/210 (57%), Gaps = 2/210 (0%)

Query: 76  VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 135
           +LCVGLNY+ H EE  L  PE P IF K    + GP + + +  D    +  E ELT+VI
Sbjct: 70  ILCVGLNYRRHAEECNLQIPENPAIFMKPSDALAGPLEDVPIHKDCQSMLDYEGELTIVI 129

Query: 136 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVTS 193
           GK    V +++  DYVLGYT+  D+ A +++    +S  Q    K+ D FCPIGP I ++
Sbjct: 130 GKDCKNVSAANFQDYVLGYTVGNDVSARNYQLPANVSGGQFGYAKSFDKFCPIGPCIAST 189

Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
             I +PQ L     +NG ++Q++ T+  I+ I  +I  LS   TL  G  ILTGTP GVG
Sbjct: 190 KVIPDPQKLTYWTKVNGEKRQETGTDDMIYTIGQVIEHLSRGTTLRAGTAILTGTPSGVG 249

Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           ++  P  FL+ GD +   ++ IG+   +++
Sbjct: 250 LFMEPKNFLKDGDEVEIYVDGIGSIINKMK 279


>UniRef50_Q7W6X4 Cluster: Putative uncharacterized protein; n=2;
           Bordetella|Rep: Putative uncharacterized protein -
           Bordetella parapertussis
          Length = 294

 Score =  161 bits (391), Expect = 2e-38
 Identities = 102/292 (34%), Positives = 146/292 (50%), Gaps = 19/292 (6%)

Query: 7   SYKNSDGIR-AGFLDG-DNVVDINKEDPKLPSTLIELLKTNXXX---XXXXXXXXXXXXL 61
           S++  DG R AG + G D +VD+  +   LP  L  L +                    L
Sbjct: 5   SFELPDGRRHAGVMTGPDTLVDLT-DAMDLPDLLTLLQRHGQLAGDVARLAAQARHTVAL 63

Query: 62  SGITLKAPVHGNDK-VLCVGLNYKDHCEEQKLTP----------PELPFIFNKFPSTVVG 110
             + + AP+    + V CVG NY +H  E   +           P  P IF+K PS+V G
Sbjct: 64  DAVRVLAPLPNPPRNVFCVGKNYHEHAREFARSGFDSSAAAGAVPAAPIIFSKPPSSVSG 123

Query: 111 PNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK 170
           P D I   +D   +V  E EL VVIGK          + +V GYT+  D+  T     K+
Sbjct: 124 PGDAIDTALDPCDSVDYEAELAVVIGKAGRVAPDDDPWSFVFGYTLVNDV--TSRGLQKR 181

Query: 171 ISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIA 230
            SQ LLGK +D +CP+GP +V++DEIG+   L + C +NG  +Q +  +  I  IP ++ 
Sbjct: 182 HSQWLLGKGIDGYCPMGPALVSADEIGDIGALEITCEVNGELRQSARLSDLIFDIPTLVR 241

Query: 231 RLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
            +   +TL PGD+I TGTP GVG+   PP++L+ GDV+    E IG  E  V
Sbjct: 242 AIGASITLQPGDVIATGTPVGVGIGFTPPKYLRRGDVVRVRAEPIGVLENPV 293


>UniRef50_Q67K64 Cluster: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1;
           Symbiobacterium thermophilum|Rep: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Symbiobacterium thermophilum
          Length = 254

 Score =  161 bits (390), Expect = 2e-38
 Identities = 89/222 (40%), Positives = 124/222 (55%), Gaps = 11/222 (4%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L  + L APV  + K++C+G NY+DH  E     PE P  F K PS ++GP + I+L  D
Sbjct: 43  LQAVQLLAPVTPS-KIVCIGRNYRDHAAELGNAAPERPMFFLKAPSALIGPGEAIRLP-D 100

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
               V  E EL VVIG++   V  + A  YV GYTIA D+   D +K         GK+ 
Sbjct: 101 PDATVHWEAELAVVIGRRMKDVAPADALSYVFGYTIANDVSHRDAQKADGAFGFGRGKSY 160

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           DTFCP GP +VT  E  +P +  +  + N   +Q  +T   IH +P++++ LS +MTL+P
Sbjct: 161 DTFCPCGPAVVT--EGIDPADALITLTCNEEVRQSDSTGLMIHPVPELLSYLSQIMTLMP 218

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GD++LTGTP GVG        ++PGD+I   I  IGT    V
Sbjct: 219 GDLVLTGTPKGVGA-------MKPGDLIEIHIPGIGTLANPV 253


>UniRef50_Q18A35 Cluster: Putative hydrolase; n=2; Clostridium
           difficile|Rep: Putative hydrolase - Clostridium
           difficile (strain 630)
          Length = 294

 Score =  161 bits (390), Expect = 2e-38
 Identities = 87/230 (37%), Positives = 129/230 (56%), Gaps = 9/230 (3%)

Query: 61  LSGITLKAPVHGNDK-VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPND 113
           L  + L +P+    K ++C+GLNYKDH  E      + +  P+ P  F+K    ++G +D
Sbjct: 67  LEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVIKNVVMPDYPIYFSKRADKIIGVDD 126

Query: 114 TIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ 173
            I L  D+ + +  E EL V+IGK+   +    A++Y+ GYTI  DI  ++     K  Q
Sbjct: 127 KISLHGDLVEKLDYESELAVIIGKEGINISKEDAYEYIFGYTIVNDI--SERALQDKHVQ 184

Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233
              GK++DT   +GP IV  +E  +P  L++   +NG  +Q SNT  FI  IP II  LS
Sbjct: 185 WFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSVVNGEVRQDSNTEYFIFDIPTIINDLS 244

Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
             MTL PGDII TGTP GV +  NP  +L+ GD++  ++E IG  +  V+
Sbjct: 245 RGMTLKPGDIISTGTPAGVAMGMNPQVYLKHGDIVECKVEGIGVLKNIVD 294


>UniRef50_A4WEA8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=6; Enterobacteriaceae|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Enterobacter sp. 638
          Length = 287

 Score =  160 bits (389), Expect = 3e-38
 Identities = 100/285 (35%), Positives = 138/285 (48%), Gaps = 9/285 (3%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX 60
           MKL  F YK       G +  D VV++ +      S L  LL+ N               
Sbjct: 1   MKLASFIYKGQRSY--GIVKADGVVNLGRRLGDRFSDLKALLQGNGMAEATRYLNDAVDV 58

Query: 61  -LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM 119
            L  IT    +   +K+LCVG+NY +  +E     P  P +F +FP +  G N  + LK 
Sbjct: 59  PLDAITFLPVIEHPEKILCVGMNYAEKRQEFDQHNPA-PTLFVRFPDSQTGHNSPV-LKP 116

Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179
             S     E EL V+IGK    +    A  +V GY+   D  A DW+     +    GK 
Sbjct: 117 RHSSEFDYEGELAVIIGKGGENISRDDALRHVAGYSCYMDGSARDWQH----TWFTAGKN 172

Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
                  GPW+ T+DEI +P  L ++  +NG   Q+ NT+  IHK+ ++I  +S    L 
Sbjct: 173 WRQTGAFGPWMATADEIPDPHRLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFTRLS 232

Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           PGD+I+TG+PGGVG  RNPP F+Q GD I  EIENIG     + E
Sbjct: 233 PGDVIITGSPGGVGKKRNPPLFMQEGDRIEVEIENIGHLSNVIME 277


>UniRef50_A6TKL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Clostridiaceae|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Alkaliphilus metalliredigens QYMF
          Length = 300

 Score =  159 bits (387), Expect = 6e-38
 Identities = 85/227 (37%), Positives = 130/227 (57%), Gaps = 9/227 (3%)

Query: 64  ITLKAPVHGN-DKVLCVGLNYKDHCEEQKL---TPPELPF---IFNKFPSTVVGPNDTIK 116
           ITL AP+      V+CVGLNY +H +E K       E+P     F+K  + V GP + I+
Sbjct: 76  ITLGAPIDRTIHDVICVGLNYAEHIDETKKGFDENMEIPLHTVYFSKRANQVKGPGEEIE 135

Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176
               +++++  E+EL V+IGK+   +    A +Y+ GYTI  D+ A   +KN    Q   
Sbjct: 136 SHSHLNESMDYEVELAVIIGKEGINISKEEAKEYIFGYTILNDLSARGLQKNHV--QWFR 193

Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236
           GK++D F  +GP IV    +G P  L++K  +N   +Q SNT   +  +  II+ +S  M
Sbjct: 194 GKSLDGFTSMGPCIVHGSSVGFPLELDIKSRVNDELRQNSNTKFMMKDVSTIISEISQGM 253

Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           TLLPGD+I TGTP GVG+   PP FL+ GD +  EI+++G  + +++
Sbjct: 254 TLLPGDVIATGTPSGVGMGFTPPRFLKAGDTVECEIQHMGLLKNKIK 300


>UniRef50_Q7WM06 Cluster: Putative oxygenase; n=3; Bordetella|Rep:
           Putative oxygenase - Bordetella bronchiseptica
           (Alcaligenes bronchisepticus)
          Length = 287

 Score =  159 bits (386), Expect = 7e-38
 Identities = 86/269 (31%), Positives = 132/269 (49%), Gaps = 4/269 (1%)

Query: 17  GFLDGDNVVDI-NKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXXLSGITLKAPVHGNDK 75
           G + G+ ++D+   + P L + L                      L+  TL AP+   DK
Sbjct: 19  GAVVGERIIDLATPQAPTLRAALARDGVDGLAARLRQADGAAGLALADATLLAPITDPDK 78

Query: 76  VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 135
           +LC+GLNY+ H EE  +  P  P  F +F  ++      + L+   S     E EL V+I
Sbjct: 79  ILCIGLNYRLHAEEAGMAIPARPSTFVRFAGSLAAQGQPV-LRPAESDQFDYEAELAVII 137

Query: 136 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 195
           GK A +V  + A ++V GY    +    DW+++   +Q   GK        GPW+VT+DE
Sbjct: 138 GKPARRVSQARAMEHVAGYACLAENSVRDWQRHS--TQATPGKNFVRSGAFGPWLVTADE 195

Query: 196 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 255
            G P+ + V   +NG   Q  +    I  +  +++ LS    LLPGD+I TGTP GVG+ 
Sbjct: 196 AGAPEAMTVIGRLNGETVQHDSVANMIFTVAQLVSYLSTFAELLPGDVIATGTPAGVGMS 255

Query: 256 RNPPEFLQPGDVITSEIENIGTFETRVEE 284
           R PP +L+PGDV   +I  +G     V++
Sbjct: 256 RKPPRYLRPGDVFEVDISGVGVLRNPVDD 284


>UniRef50_A3XC82 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=3; Alphaproteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Roseobacter sp. MED193
          Length = 285

 Score =  159 bits (385), Expect = 1e-37
 Identities = 81/216 (37%), Positives = 114/216 (52%), Gaps = 2/216 (0%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           ++G  L  PV     + CVGLNY DH  E  L  PE P +FNK   T  GPND I     
Sbjct: 60  VAGKPLAPPVAQPLNIWCVGLNYSDHAAEAGLPVPEEPILFNKSTVTYCGPNDDILKSAQ 119

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           +SK +  E+EL +VI K A  +    A D++ G+ +  DI    W+  +   Q + GK+ 
Sbjct: 120 MSK-LDWEVELGIVISKPALNISRDQAMDHIAGFVLVNDISERAWQMERS-GQWVKGKSF 177

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
             FCP GP + T +E  + QNL +   +NG + Q  NT   I  +  I++ +S    L P
Sbjct: 178 PNFCPTGPVLATKEEFADVQNLGMWLDVNGERMQTGNTGTMIFDVATIVSYMSEFTRLEP 237

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
           GD+I TGTP GVG    PP +L  GD ++  I+ +G
Sbjct: 238 GDLICTGTPPGVGAGMTPPVWLNEGDKVSLGIDGLG 273


>UniRef50_A1SD71 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=5; Bacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 284

 Score =  158 bits (384), Expect = 1e-37
 Identities = 79/212 (37%), Positives = 121/212 (57%), Gaps = 3/212 (1%)

Query: 66  LKAPVHGNDKVLCVGLNYKDHCEEQKL-TPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 124
           L AP     + + +GLNY++H  E     P +LP +F KF S++ GP   + L       
Sbjct: 68  LGAPSPRPTQAIAIGLNYEEHAHETGYQVPTQLPPVFAKFASSITGPRGLVDLPP--GGH 125

Query: 125 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 184
              E+E+  VIG+ A ++    A+ +V G T+ QD+     +      Q  L K+   F 
Sbjct: 126 TDWEVEVVAVIGRTAHRISPDEAWGHVAGLTVGQDLSERISQMAGPAPQFGLAKSFPGFS 185

Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244
           P+GPW+VT +E+ +P +L + C+I+G   Q   T++ I  IP  IA LS V+TLLPGD++
Sbjct: 186 PMGPWLVTPEELADPDDLALGCAIDGETVQDGRTSKLIFSIPRSIAALSQVLTLLPGDVV 245

Query: 245 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
            TGTP GVG+ R+P  FL+PG+ + + +E IG
Sbjct: 246 FTGTPDGVGLGRSPQRFLRPGETLRTWVEGIG 277


>UniRef50_Q0CVN6 Cluster: Predicted protein; n=1; Aspergillus
           terreus NIH2624|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 274

 Score =  158 bits (384), Expect = 1e-37
 Identities = 81/204 (39%), Positives = 121/204 (59%), Gaps = 4/204 (1%)

Query: 76  VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTVV 134
           V C+GLNYK+H  E K+T P+ P +F K  + +    + I L   V       E+EL ++
Sbjct: 65  VRCIGLNYKEHAAEMKMTLPDAPTVFLKANTCISSAAEPIVLPSVVDHDEADYEVELAII 124

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IG++   V  + A  YVLGY++A D+ A   +   K SQ    K MD FCP+GP IV+++
Sbjct: 125 IGQRCKNVSVAEAMGYVLGYSVANDVTAR--KHQGKTSQWSYAKGMDGFCPLGPCIVSAE 182

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           +I +P    ++ S+NG   Q ++ +  I  I ++++ LS   TLLPG +I+TGTP G+GV
Sbjct: 183 KIPDPSVFQLRTSLNGKTMQNASADDMIFSIAEVVSYLSQGHTLLPGTVIITGTPCGIGV 242

Query: 255 YRNPPEFLQPGDVI-TSEIENIGT 277
            +NPP FL+PGD +  S    IGT
Sbjct: 243 SQNPPVFLKPGDRLRISASHGIGT 266


>UniRef50_Q41AV1 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Exiguobacterium sibiricum
           255-15|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Exiguobacterium sibiricum 255-15
          Length = 277

 Score =  158 bits (383), Expect = 2e-37
 Identities = 84/222 (37%), Positives = 121/222 (54%), Gaps = 3/222 (1%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           I L AP      V+CVG NY DH +E          +F K PS++VGP + I+   D+++
Sbjct: 58  IRLLAPYIPPRNVICVGKNYADHIKEMDTAGAGKFVLFTKAPSSIVGPFEAIERHADLTQ 117

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183
            +  E EL ++IG     +   +A D+V GY+I  D+ A D +K     Q   GK++D F
Sbjct: 118 QLDYEGELAIIIGTSGRDLTPENALDHVFGYSIVNDVTARDLQKEHV--QFFRGKSLDGF 175

Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243
           CP GP IVT D   +P ++ V+  +NG  +Q  +T   +  +  I+  +S  MTL  GDI
Sbjct: 176 CPFGPVIVTEDSF-DPTDVLVETRVNGQLRQSGSTKLMLRDVVTILTEVSRGMTLEAGDI 234

Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285
           I TGTP GVG    PP +LQ GDV+   IE IG  +  V+ +
Sbjct: 235 IATGTPAGVGHGMKPPTYLQDGDVVDISIEGIGHLQNHVKAY 276


>UniRef50_Q0G5A5 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=2; Proteobacteria|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Fulvimarina pelagi HTCC2506
          Length = 337

 Score =  157 bits (382), Expect = 2e-37
 Identities = 76/211 (36%), Positives = 122/211 (57%), Gaps = 2/211 (0%)

Query: 66  LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125
           L AP+      + +GLNY DH  E     P  P +F+K PS++ GP+D + +    +K +
Sbjct: 117 LGAPIARVGHFIAIGLNYADHAAETGADLPVEPLVFSKAPSSICGPHDELPIPPGSTK-L 175

Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185
             E+EL VVIG++A  ++ + A ++V G+ +  D+    ++K +   Q + GK+      
Sbjct: 176 DWEVELAVVIGERAYNINETEAMNHVAGFCLCNDVSERAFQKERG-GQFIKGKSSPRTGA 234

Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
           +GPW+VT D +G+PQ L++  S+NG  +Q+  T   +     I++ LS  M L PGD+I 
Sbjct: 235 LGPWLVTPDRLGDPQQLDLWLSVNGEIRQRGTTRDMLFSAAFIVSYLSKFMILEPGDVIT 294

Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
           TGTP GVG    PP+FL+ GD++T  I  +G
Sbjct: 295 TGTPSGVGAGMTPPQFLREGDILTLGIGGLG 325


>UniRef50_Q9KBC3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Bacillus halodurans|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase - Bacillus
           halodurans
          Length = 276

 Score =  157 bits (380), Expect = 4e-37
 Identities = 89/224 (39%), Positives = 132/224 (58%), Gaps = 13/224 (5%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKL--TPPELPFIFNKFPSTVVGPNDTIKLK 118
           L+ + L+ P+    K++   +NY  H +E  +  T   L F F K  ++++GPND I L 
Sbjct: 61  LNDVRLRQPLSRPGKIVAAPVNYMSHKKEMNVDHTARVLGF-FLKATTSIIGPNDPIILP 119

Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGK 178
            + ++ +  E+EL  VIGK+A  V   +A DY+ GYT   D+      KN++  +  L K
Sbjct: 120 YN-NRRIDHELELAFVIGKRAKHVKKENAHDYIFGYTGLNDVTVRP-TKNRE-EERCLRK 176

Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTL 238
           + DTF PIGPWIVTSDEI +PQNL +   +N   +Q  NTNQ +  I +++   S+VMTL
Sbjct: 177 SFDTFTPIGPWIVTSDEIKDPQNLTISLQVNHEVRQHVNTNQMVCGIAELVEIFSHVMTL 236

Query: 239 LPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
            PGD+I TGTP GVG        ++ GD +T ++E+IG+F   V
Sbjct: 237 EPGDLIATGTPDGVGP-------IKDGDTVTLQMESIGSFSNPV 273


>UniRef50_Q11EA1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=5;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Mesorhizobium sp. (strain BNC1)
          Length = 287

 Score =  156 bits (379), Expect = 5e-37
 Identities = 91/289 (31%), Positives = 149/289 (51%), Gaps = 14/289 (4%)

Query: 1   MKLLQFSYKNSDGIRA-GFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXX 59
           MKL  F++    G+R  G ++   VVD+   +P+LP+ ++ +L+                
Sbjct: 1   MKLALFTH---GGVRRIGLVERGEVVDLLSGNPRLPNDMVAILEGGAETLEAVRLAAGRA 57

Query: 60  ---XLSGITLKAPVHGNDKVLCVGLNYKDHCEEQK---LTPPELPFIFNKFPSTVVGPND 113
               L+ + L AP+    K L +GL++K   +E +   +  PE    FNK  + + GP D
Sbjct: 58  NRLALNEVQLNAPITRPRKFLGLGLSFKSSADEFRAKGVAIPEHQVWFNKQVTAINGPYD 117

Query: 114 TIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ 173
            + +   VS  +  E EL +VIGK+     +S A   + G+ +  D    DW++    + 
Sbjct: 118 PVHMPR-VSSELDYEGELALVIGKRIRHARTSDAEKIIAGFLVCNDFSVRDWQRRSPTAT 176

Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233
           L  GK+ DT  PIGPW+ T DE+ +P +L ++  ++G  +Q  NT+  ++   ++IA LS
Sbjct: 177 L--GKSFDTHGPIGPWLTTFDEV-DPSSLRIRTWVDGELRQDGNTDDLLYTFGEMIAELS 233

Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
              TL PGDI+ TG+P G G Y  PP +L+ G  +  EIE +G  E  +
Sbjct: 234 TAFTLEPGDILATGSPTGAGQYMRPPTYLKTGQTVRVEIEGLGHIENMI 282


>UniRef50_A5VAQ6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 282

 Score =  156 bits (379), Expect = 5e-37
 Identities = 87/216 (40%), Positives = 117/216 (54%), Gaps = 4/216 (1%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L  + L  P+   DKVLCV  N+++   E K   PE P +F +F ++  G    +  K D
Sbjct: 58  LDQVRLLPPIPNPDKVLCVATNFREPAREGK-PEPEYPLVFTRFANSFTGHGQPLA-KPD 115

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
            S+A   E EL VVIGK   ++ +S A  +V GY    D    DW+K+   +Q   GK  
Sbjct: 116 RSEAYDFEGELAVVIGKGGHRIPASEAMAHVGGYCCLNDGSVRDWQKHS--TQFTPGKNF 173

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
                 GPWIVT+DEI +P  L ++  +NGV KQ+   ++ I  IP +IA  S    L+P
Sbjct: 174 HRSGSFGPWIVTADEIPDPTVLTLQTRVNGVVKQRIGIDRMIFDIPWLIAYFSTFTPLVP 233

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
           GD+I TGTP G G  R PPE+L  GD I  EI  IG
Sbjct: 234 GDVIATGTPSGFGSSRTPPEYLSIGDAIEVEISEIG 269


>UniRef50_UPI000023DA6E Cluster: hypothetical protein FG11179.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG11179.1 - Gibberella zeae PH-1
          Length = 281

 Score =  155 bits (377), Expect = 9e-37
 Identities = 87/225 (38%), Positives = 123/225 (54%), Gaps = 8/225 (3%)

Query: 66  LKAPVHGND--KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           L  P+  ND   V+C+GLNY DH EE ++  P++P +F K  + + GP+D + L     +
Sbjct: 54  LLCPIDLNDARSVVCIGLNYTDHAEEAQMPIPKVPVVFFKPVTALAGPHDDLVLPHTSWE 113

Query: 124 A--VVCEIELTVVIGKKASKVDSSHAFDYVLGYTI--AQDIGATDWEKNKKIS--QLLLG 177
              +  E EL +VIGKKAS+V    A DYV  YT     DI    W+ + ++   Q    
Sbjct: 114 KGRLDYESELVIVIGKKASRVSKDDALDYVFSYTFHAGNDISNRAWQLDPQLGGGQWCYS 173

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           K  D   PIGP IV+ D +G+   L ++ ++N  Q Q  NTN  I  + +I++ LS  MT
Sbjct: 174 KCFDCSAPIGPAIVSKDILGSAVGLGIRGTLNDTQSQDGNTNNMIFGVAEIVSFLSQGMT 233

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           LLPG  I TGTP GVG  + P   ++ GDV   EI+ IG    +V
Sbjct: 234 LLPGTFIFTGTPAGVGFGKKPQISVKEGDVTQVEIDGIGAIVNKV 278


>UniRef50_Q88Y59 Cluster:
           2-hydroxyhepta-2,4-diene-1,7-dioateisomerase /
           5-carboxymethyl-2-oxo-
           hex-3-ene-1,7-dioatedecarboxylase; n=1; Lactobacillus
           plantarum|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioateisomerase /
           5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioatedecarboxylase
           - Lactobacillus plantarum
          Length = 276

 Score =  155 bits (375), Expect = 2e-36
 Identities = 76/218 (34%), Positives = 120/218 (55%), Gaps = 3/218 (1%)

Query: 66  LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125
           L AP+    ++  VG+NY+DH  E  +T P++P IF KF S++   N T+          
Sbjct: 62  LAAPITAPRQIFAVGMNYRDHSAEIHITLPKVPSIFTKFSSSLAPANVTMATH---GPET 118

Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185
             E EL V+IGK    + ++ A  +V G  + +D+     +      Q  +GK+ + + P
Sbjct: 119 DWETELVVMIGKGGRDIATADAMAHVAGVMVGEDLSDRAVQFENDNPQFSIGKSFENYAP 178

Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
           +GPW+ T DE+ N  +  +  ++NG   Q++  +Q I K+PD++  LS V  L PGD+I 
Sbjct: 179 VGPWLTTVDELANLDDEVITTTVNGQTMQQAPLSQLIFKVPDLVHYLSTVCELQPGDLIF 238

Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           TGTP G GV RNP  FLQ GD +  +I ++GT    ++
Sbjct: 239 TGTPSGTGVGRNPQVFLQAGDQLCGQITHLGTLNITIK 276


>UniRef50_Q5Z0F5 Cluster: Putative hydrolase; n=1; Nocardia
           farcinica|Rep: Putative hydrolase - Nocardia farcinica
          Length = 285

 Score =  155 bits (375), Expect = 2e-36
 Identities = 80/209 (38%), Positives = 116/209 (55%), Gaps = 3/209 (1%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTV 133
           K++C G NY+ H  E     PE P +F KF  T+   +  I L M  + A +  E EL V
Sbjct: 62  KIVCCGHNYRAHIAELGRAEPEFPTLFAKFADTLTAWDADITLGMAAADAGLDWEAELAV 121

Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193
           V+G +  + D + A   + GYT+A D     W++  + +Q L GKA D   P+GP +VT 
Sbjct: 122 VVGAELRRADRATARAGIAGYTVANDFSVRTWQR--RTAQWLQGKAFDATTPLGPDLVTP 179

Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
           DE      L + C +NGV +Q  +T+  +     +++ +S   TL PGD++LTGTPGGVG
Sbjct: 180 DEADPGDGLRITCRVNGVVEQCGSTDDLLFDPAALLSYISAFTTLRPGDVVLTGTPGGVG 239

Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRV 282
           V  +PP  L  GDV+ +EIE IG    R+
Sbjct: 240 VAADPPRHLGDGDVVETEIEGIGLLRNRI 268


>UniRef50_A0RY21 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase;
           n=1; Cenarchaeum symbiosum|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase -
           Cenarchaeum symbiosum
          Length = 288

 Score =  154 bits (373), Expect = 3e-36
 Identities = 83/222 (37%), Positives = 122/222 (54%), Gaps = 3/222 (1%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           LS   + AP+    K+ C+  NY DH ++Q  +PP+ P I  K  + + G  D I +   
Sbjct: 65  LSEYGIMAPIAEPPKIFCLAFNYADHAQDQDRSPPDEPVIVMKPRTALCGNGDDIVMPPF 124

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           V K +  E+EL ++IGK+   VD   A + + GYTI  D+ A D +      Q    K +
Sbjct: 125 V-KELDYEVELALIIGKRCRDVDVIGAKEAIFGYTILNDVSARDIQFRD--GQFTRAKGL 181

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           DTF P GPWI ++DE+ +P  L +   +NG  +Q S+T++   K  +I+++LS+ MTL  
Sbjct: 182 DTFAPCGPWITSADEVQDPGRLKMTTKVNGRARQDSSTSKMHIKPFEIVSKLSSSMTLEK 241

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GDII TGTP GV +     E+L  GD I  EIE +G     V
Sbjct: 242 GDIISTGTPSGVALNNPDSEYLAAGDEIEMEIEGLGVLRNTV 283


>UniRef50_Q193D4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Desulfitobacterium hafniense|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Desulfitobacterium hafniense (strain
           DCB-2)
          Length = 251

 Score =  153 bits (372), Expect = 4e-36
 Identities = 89/219 (40%), Positives = 123/219 (56%), Gaps = 14/219 (6%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           + L APV    K++C+GLNY  H EE      + P IF K  +++VGP D I L   +S+
Sbjct: 46  VRLLAPVEPT-KIVCIGLNYAKHIEELGHDFHDDPVIFLKPVTSLVGPEDEIILPA-MSQ 103

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183
            V  E EL VVIGK A  +    A DY+ G+T   D+ A D +K  K  Q    K  DTF
Sbjct: 104 QVDYEAELVVVIGKTAKDLAEDQAEDYIFGFTCGNDVTARDLQK--KDGQWTRSKGFDTF 161

Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243
           CPIGPWIV   +    +N+ ++  +NG  KQ S T+  IH +P +++ +S +MTL PGD+
Sbjct: 162 CPIGPWIVRDLDY---RNVKIRSVLNGEVKQSSQTSHLIHSVPKLVSYISKIMTLNPGDL 218

Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           I+TGTP GVG        ++ GD I  +I+ IG     V
Sbjct: 219 IMTGTPEGVGP-------MKTGDAIAIDIKGIGRLHNLV 250


>UniRef50_Q9HK55 Cluster: Probable 2-hydroxyhepta-2, 4-diene-1,
           7-dioate isomerase; n=1; Thermoplasma acidophilum|Rep:
           Probable 2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase
           - Thermoplasma acidophilum
          Length = 315

 Score =  153 bits (372), Expect = 4e-36
 Identities = 88/217 (40%), Positives = 124/217 (57%), Gaps = 10/217 (4%)

Query: 68  APVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 127
           APV  + K+LC+G+NY +H +E +    E P IF KF  +++G  D I +  D +K +  
Sbjct: 106 APVLRSGKILCIGVNYMEHAKESRQKVMEHPTIFCKFQDSIIGNMDDITVPKD-AKQIDY 164

Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187
           E EL V+IG+ +   +SS     + GYTI  D+ A D +   + SQ LLGKA+ TF PIG
Sbjct: 165 EGELVVIIGRSSGTAESS-----IFGYTIGNDVSARDLQF--RTSQWLLGKALPTFAPIG 217

Query: 188 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247
           P IV  +E+G  ++L +   +NG  +Q  NT+  I  +  I+  LS    L PGDII TG
Sbjct: 218 PVIVGKNELGFARDLQIITRVNGTVRQNGNTSDMIFDVRAIVDYLSGYFNLGPGDIIFTG 277

Query: 248 TPGGV--GVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           TP GV  G+  N   +L+ GDVI   I  IGT   R+
Sbjct: 278 TPEGVILGLPENERVWLKHGDVIDVSITGIGTLTNRI 314


>UniRef50_Q6M0X4 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=7; cellular organisms|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Methanococcus maripaludis
          Length = 202

 Score =  153 bits (372), Expect = 4e-36
 Identities = 86/209 (41%), Positives = 121/209 (57%), Gaps = 13/209 (6%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++C GLNYKDH EE K+  P+ P IF K  S+++   + IK+    S+ V  E EL +V
Sbjct: 7   KIVCAGLNYKDHAEELKMKLPKEPVIFLKPTSSIIYNEEAIKIPK-ASERVDYEAELAIV 65

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IGK    V      +Y+ G+TI  D+ A D ++  K  Q    K+ DTF PIGP IV+  
Sbjct: 66  IGKTCKSVKKEDVKNYIKGFTILNDVTARDLQE--KDGQWTRAKSFDTFSPIGPKIVSGI 123

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           +  N   L ++  +NG  KQ SNTN  I  + +++  +S++MTL PGDII TGTP G+G 
Sbjct: 124 DANN---LKIQLRVNGKIKQDSNTNNMIFSVEELVEFVSSIMTLYPGDIISTGTPPGIGK 180

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRVE 283
                  L+ GD++  EIENIG  +  VE
Sbjct: 181 -------LEKGDIVEIEIENIGILKNFVE 202


>UniRef50_A5P4N8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Methylobacterium sp. 4-46|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Methylobacterium sp. 4-46
          Length = 480

 Score =  152 bits (369), Expect = 9e-36
 Identities = 78/213 (36%), Positives = 118/213 (55%), Gaps = 6/213 (2%)

Query: 74  DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133
           +K++ +G NY+ H  E     P+ P +FNK+ + +     TIKL   V++    E+EL +
Sbjct: 269 EKIIMMGFNYRHHAAETGTPIPKDPPLFNKYNNALNHHGGTIKLPTAVAREFDYEVELVI 328

Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193
           V G++ S V  + A D V GY    D  A D +     SQ ++GK  D F P+GP++VTS
Sbjct: 329 VFGRECSNVSEAEALDCVAGYATGNDFSARDLQT--LTSQFMIGKTADGFAPLGPYLVTS 386

Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
           D + +P NL ++  +NGVQ+Q  NTN  I     +I+  S +MT+ PGDI  TGTP GV 
Sbjct: 387 DLVKDPNNLRLETRVNGVQRQDWNTNDMIFNCRQLISFASKMMTIKPGDIFYTGTPHGVI 446

Query: 254 VYRNPP----EFLQPGDVITSEIENIGTFETRV 282
                P    ++L+PGD +   +E +G    R+
Sbjct: 447 FGEKKPRAERQWLKPGDEVACSLEGLGELRFRL 479


>UniRef50_Q8Y512 Cluster: Lmo2266 protein; n=13; Listeria|Rep:
           Lmo2266 protein - Listeria monocytogenes
          Length = 282

 Score =  152 bits (368), Expect = 1e-35
 Identities = 92/287 (32%), Positives = 148/287 (51%), Gaps = 9/287 (3%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDN-VVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXX 59
           MK L + Y+    +  G L  +N ++         P+TL++ +K                
Sbjct: 1   MKWLSYLYEGD--LAYGILTPENKIIPAGTIFSNPPATLLDFIKEKPLVPELTGIDGHID 58

Query: 60  XLSGITLKAPVHGNDKVLCVGLNYKDHCEEQ--KLTPPELPFIFNKFPSTVVGPNDTIKL 117
            L+ + ++ P    + ++ +G NY +H  E   K   PE   +F K  ++++  N  I+L
Sbjct: 59  -LAEVEIQVPFVPPNNIIAIGKNYYNHVLEMGSKEDVPEHILVFTKSANSLLPHNGNIEL 117

Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177
             +++  +  E EL V+IG+K   +    A   + G+TI  DI A D +K  K  Q  LG
Sbjct: 118 HQNITGQLDYEGELAVIIGEKVRDISEQEALSAIFGFTILNDITARDLQKKHK--QFYLG 175

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           K++D  CPIGP+++ ++    P   +++  +NG  +Q  +T++FI  +  II+ LS   T
Sbjct: 176 KSLDASCPIGPFVLENNANKEPV-FHIETKVNGEVRQSDSTDKFIFGLARIISDLSKGHT 234

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           LLPGDII TGTP GVG    PP FLQ GD+I   I+ IGT   +V +
Sbjct: 235 LLPGDIIATGTPSGVGNGMTPPTFLQDGDIIEITIDKIGTLTNKVRK 281


>UniRef50_A0V486 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=4; Bacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Delftia acidovorans SPH-1
          Length = 309

 Score =  151 bits (366), Expect = 2e-35
 Identities = 79/219 (36%), Positives = 117/219 (53%), Gaps = 4/219 (1%)

Query: 65  TLKAPVHGND-KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           T   PV  N  K++CVGLNYK H  E +    E P +F +F  ++    D + L+   S+
Sbjct: 87  TQALPVIPNPGKLICVGLNYKTHVAETRRADSEHPSLFLRFNDSLAADGDEL-LRPAFSE 145

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183
               E EL  VIG+    +    AFD++ GY    D+   DW+++    Q   GK     
Sbjct: 146 RFDWEGELAFVIGRGGRHIAKEDAFDHIAGYACFNDVSVRDWQRHTH--QFTPGKNFPGT 203

Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243
            P GPW+VT DE+ + ++L ++  +NG   Q+++    I  IP I+A +S    L PGD+
Sbjct: 204 APFGPWLVTRDEVADVRSLALQTRLNGSVMQQASLGDLIFDIPTIVAYVSRFTPLSPGDV 263

Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           I TGTPGGVG  R PP +++ GDV+  EI  +G    R+
Sbjct: 264 IATGTPGGVGDRREPPLYMKHGDVVEVEITGLGVLRNRI 302


>UniRef50_A5VE85 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 356

 Score =  151 bits (365), Expect = 3e-35
 Identities = 80/221 (36%), Positives = 119/221 (53%), Gaps = 3/221 (1%)

Query: 62  SGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV 121
           S +T   PV   DK++ VG NY+ H  E     P+ P +F +FPS+ VG    + +   +
Sbjct: 127 SSLTFLPPVTDPDKIIAVGFNYRGHLIETGTPLPDYPSLFVRFPSSQVGHGQPV-VAPSL 185

Query: 122 SKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMD 181
           S     E EL V+IG+ A +V  + A D+V+GY+   +    D++ + +  Q+  GK   
Sbjct: 186 SGEFDFEGELAVIIGRPAWRVAEADAMDHVVGYSCFAENSVRDYQAHAR--QVTAGKNFL 243

Query: 182 TFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241
               IGPW+ T+DE+G+P  L +   +NG   Q+      I  IP +IA ++    LLPG
Sbjct: 244 ASGAIGPWLTTADEVGDPSTLELTTRLNGAVVQQDRLTSLIFTIPQLIAYITRFTRLLPG 303

Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           DII TGTP GVG  R+P  +L PGDV+  +I  +G     V
Sbjct: 304 DIISTGTPDGVGFLRDPKIWLAPGDVLEIDIPRVGLLRNAV 344


>UniRef50_UPI00015C5CCD Cluster: hypothetical protein CKO_03358;
           n=1; Citrobacter koseri ATCC BAA-895|Rep: hypothetical
           protein CKO_03358 - Citrobacter koseri ATCC BAA-895
          Length = 295

 Score =  150 bits (364), Expect = 3e-35
 Identities = 95/285 (33%), Positives = 136/285 (47%), Gaps = 9/285 (3%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXX-XXX 59
           MKL  F Y+ +     G +    V+D+          L  LL+ +               
Sbjct: 9   MKLASFLYQGTRSY--GIVTAGGVIDLGNRIGDQYRDLKALLQGDGLEQARRFAQAPVDL 66

Query: 60  XLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKM 119
            +  IT    +   +K+LCVG+NY +  +E     P  P +F +F  +  G N  + LK 
Sbjct: 67  KMDAITFLPVIERPEKILCVGMNYAEKRQEFDQHDPA-PTLFVRFADSQTGHNMPV-LKP 124

Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179
             S     E EL V+IG     +   HA D+V GY+   D  A DW+     S    GK 
Sbjct: 125 RHSHEFDYEGELAVIIGNGGENISRDHALDHVAGYSCYMDGSARDWQH----SWFTAGKN 180

Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
                  GPW+VT+DEI +P  L ++  +NG   Q+ NT+  IHK+ ++I  +S    L 
Sbjct: 181 WRQTGAFGPWMVTADEIPDPHQLAIRTWLNGRMVQEDNTSSMIHKVAELIEYISTFTRLN 240

Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
            GD+I+TG+PGGVG  RNPP F+Q GD I  EIE+IG     + E
Sbjct: 241 SGDVIITGSPGGVGKKRNPPLFMQEGDRIEVEIEHIGHLSNVIME 285


>UniRef50_A3TUH0 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Oceanicola batsensis HTCC2597|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Oceanicola batsensis HTCC2597
          Length = 252

 Score =  150 bits (364), Expect = 3e-35
 Identities = 90/222 (40%), Positives = 121/222 (54%), Gaps = 14/222 (6%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           LS + L  PV    K++CVGLNYK H EE     PE P +F   PS V+    TI L   
Sbjct: 42  LSDVALLPPVEPG-KLVCVGLNYKRHAEESGAAIPEEPMLFMCAPSAVIPDGGTILLDSQ 100

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
            ++ +  E E+ +VIGK+A  +  + A   + GYTI  D+   D++K  K  Q    K+ 
Sbjct: 101 DAR-IDYEAEIAIVIGKQARNLPEADARSCIFGYTICNDVSNRDYQK--KDGQFTRAKSF 157

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           DT+ P+GPWI T  +   P N  +    NG  +Q+SNT+  I  I  I+A +S +MTL P
Sbjct: 158 DTYKPLGPWIETGLD---PDNAAISLRQNGELRQQSNTSDMIFSIDRIVAFVSGIMTLNP 214

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GD+I+TGTP GVG  R+       GD I  EIE IGT    V
Sbjct: 215 GDVIITGTPEGVGPMRS-------GDRIEIEIEGIGTLANSV 249


>UniRef50_Q0C3X7 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Hyphomonas neptunium ATCC 15444|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 277

 Score =  150 bits (363), Expect = 5e-35
 Identities = 84/226 (37%), Positives = 119/226 (52%), Gaps = 7/226 (3%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQ----KLTPPELPFIFNKFPSTVVGPNDTIK 116
           LS + L APV    K+L +G+NY  H  E         PE+   FNK  + V GP D + 
Sbjct: 45  LSVVRLLAPVPRPRKILGIGVNYAAHAAESVSFINTAKPEVQKWFNKQATAVNGPYDPVH 104

Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176
           L   VS  +  E EL  VIGK    V +  A + V G+ I  D    DW+K  +   +++
Sbjct: 105 LPR-VSSQLDYEGELVAVIGKHGRHVPAERAMEIVAGFCIGCDYSVRDWQKASQT--MIM 161

Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236
           GK  DT  P GP +VT DE+G+  +L ++  +NG  +Q       IH +   IA L+   
Sbjct: 162 GKGFDTHAPFGPALVTPDELGDISDLEIRSFVNGELRQSGRPRDMIHDVGAQIAHLTAAF 221

Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           TL PGD+I TGTP GVG   +PP++L+ GD +  EI+ +G  E  +
Sbjct: 222 TLEPGDVIFTGTPAGVGAGFDPPKWLKAGDRVRIEIDRLGHIENAI 267


>UniRef50_Q8TWN0 Cluster: 2-keto-4-pentenoate hydratase hydratase;
           n=1; Methanopyrus kandleri|Rep: 2-keto-4-pentenoate
           hydratase hydratase - Methanopyrus kandleri
          Length = 264

 Score =  150 bits (363), Expect = 5e-35
 Identities = 88/219 (40%), Positives = 126/219 (57%), Gaps = 16/219 (7%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQK---LTPPELPFIFNKFPSTVVGPNDTIKL 117
           LS + +  PV    K++C GLNY++H EE +   +  P  P +  K P+ V+G  DT+KL
Sbjct: 51  LSELRIGPPVPRPPKIICFGLNYREHVEELREMGMDVPSEPVMTMKAPTAVIGHLDTVKL 110

Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177
             + ++ V  E+EL VVIG++  KV    A D VLG+TI  D+ A D EK +   Q +  
Sbjct: 111 PRE-ARRVDHELELAVVIGERCRKVSPEEARDAVLGFTIINDVTARDIEKRE--GQWVRA 167

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           K+ DTF P+GPWI T  E   P  L ++  +NG  +Q++ T+  +    ++++  S VMT
Sbjct: 168 KSYDTFAPLGPWIETELE---PDGLEMELRVNGEVRQRATTDDMVRDPYELVSFTSRVMT 224

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
           L PGDII TGTP GVG        ++P D I  EIE IG
Sbjct: 225 LEPGDIIATGTPPGVGP-------MEPDDKIELEIERIG 256


>UniRef50_Q2U1K8 Cluster: RIB40 genomic DNA, SC138; n=4;
           Pezizomycotina|Rep: RIB40 genomic DNA, SC138 -
           Aspergillus oryzae
          Length = 582

 Score =  149 bits (362), Expect = 6e-35
 Identities = 85/231 (36%), Positives = 127/231 (54%), Gaps = 14/231 (6%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEE---------QKLTPPELPFIFNKFPSTVVGP 111
           LS +    P+ G D VL VG NY +H +E          K   P  P IF K  ++++GP
Sbjct: 66  LSSVKHLPPISGRD-VLAVGKNYVEHAKEFNASGYDASDKSDQPTHPVIFTKRATSIIGP 124

Query: 112 NDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKI 171
            + I L    +  V  E E+ V+IGK   ++   +A D+V GYTI  D+ A + +++ K 
Sbjct: 125 EEPILLHPKFTSTVDYEGEIGVIIGKPGFQISEENASDHVWGYTIVNDMTARERQRDHK- 183

Query: 172 SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIAR 231
            Q  LGK+ DTFCP+GP  V  + +  P+NL ++  +N   +Q+++ +  I  IP +IA 
Sbjct: 184 -QFFLGKSPDTFCPMGPVAVPKESL--PENLKIQTFVNQELRQEASLSDLIFSIPTLIAT 240

Query: 232 LSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           +S   TL  GD+I TGTP GVG    P +FLQ GD I+  +  +GT   R+
Sbjct: 241 ISAGQTLQTGDVIATGTPAGVGFGFRPMKFLQTGDEISVSVTGLGTLTNRM 291


>UniRef50_Q39LG9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Burkholderiaceae|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 306

 Score =  149 bits (360), Expect = 1e-34
 Identities = 87/226 (38%), Positives = 125/226 (55%), Gaps = 11/226 (4%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQ--KLTPPE--LPFIFNKFPSTVVGPNDTIK 116
           L+G  L+ P +   ++     NY +H  E   +L P E   P++F K  ++VV P     
Sbjct: 79  LAGYRLRVP-YAPRRIFAAASNYYEHAREMGTELAPREESTPYMFMKAETSVV-PTLAEV 136

Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS---Q 173
           +    ++ V  E+EL VVIGK    +  + AFDYV GYTI  D+ A D  +         
Sbjct: 137 VMPPHAERVDWEVELAVVIGKPGRHIAVADAFDYVAGYTILNDVSARDLNRRTDYPFKHD 196

Query: 174 LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233
              GK+ DTF P+GPW+V    I  PQNL ++ ++NG   Q  NT + I  I + I  LS
Sbjct: 197 WFRGKSFDTFGPLGPWLVPRACIAEPQNLRMRLAVNGEMMQDGNTGEMIFSIAEQIHYLS 256

Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFE 279
           +++TL PGD+I TGTP GVG+ R    +LQPGDV+ + I+ IG+ E
Sbjct: 257 SILTLQPGDLIATGTPTGVGMGRG--IYLQPGDVMVASIDGIGSIE 300


>UniRef50_O28058 Cluster: Uncharacterized protein AF_2225; n=3;
           cellular organisms|Rep: Uncharacterized protein AF_2225
           - Archaeoglobus fulgidus
          Length = 250

 Score =  148 bits (358), Expect = 2e-34
 Identities = 85/202 (42%), Positives = 118/202 (58%), Gaps = 13/202 (6%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++ VGLNY DH EE  +  PE P +F K  + V+G +D I L   +S+ V  E EL VV
Sbjct: 45  KIIAVGLNYIDHAEELNMPVPEEPILFMKPSTAVIGHDDCIILPQ-ISQRVDYEGELAVV 103

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           I +    V  ++A DY+LGYT   D+ A D +   K  Q    K+ DTF P+GP+I    
Sbjct: 104 IAEDCRNVPETNAADYILGYTCFNDVTARDLQA--KDGQWTRAKSFDTFAPLGPYIA--- 158

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           EI +P  L ++  +NG   QKSNT+  I  +  +++ +S+VMTL  GD+I TGTP GVG+
Sbjct: 159 EIDDPSKLGIQTRVNGKVVQKSNTSNLIFDVFQLVSFVSSVMTLKAGDVIATGTPAGVGM 218

Query: 255 YRNPPEFLQPGDVITSEIENIG 276
                  L+ GDV+  EIE IG
Sbjct: 219 -------LKDGDVVEVEIEKIG 233


>UniRef50_A6M380 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Clostridium beijerinckii NCIMB
           8052|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Clostridium beijerinckii NCIMB 8052
          Length = 294

 Score =  147 bits (355), Expect = 4e-34
 Identities = 86/231 (37%), Positives = 122/231 (52%), Gaps = 10/231 (4%)

Query: 61  LSGITLKAPV-HGNDKVLCVGLNYKDHCEEQKLTPPEL-----PFI--FNKFPSTVVGPN 112
           +  I+   P+ + N  ++C+G+NY +H  E      E      P+   F+K  +T     
Sbjct: 66  IENISKMPPIPNPNQDIICLGINYMEHAVESARYKNEAFGGDRPYAVYFSKRVNTATADG 125

Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS 172
           D I     +  ++  E EL V+IGK A  V    AFDYV GYTI  D+ A + +   K  
Sbjct: 126 DYIPSYPQIVDSLDYEAELAVIIGKDAKDVPKEKAFDYVFGYTIINDVSARNLQTRHK-- 183

Query: 173 QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 232
           Q   GK++D F P+GP IVT +E  NP  L +   +NG  +Q S T+  I  I D+I  L
Sbjct: 184 QWYFGKSLDGFTPMGPCIVTKNEFVNPPVLRICSRVNGELRQNSTTDLMITSIQDVIHEL 243

Query: 233 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           S  +TL  G II  GTP GVG+   PP+FL+ GD++  EIE IG  +  V+
Sbjct: 244 SQGITLKVGTIIAMGTPAGVGMGFIPPKFLKTGDIVECEIEGIGCLKNIVK 294


>UniRef50_Q7ML43 Cluster: Putative uncharacterized protein VV1584;
           n=2; Vibrio|Rep: Putative uncharacterized protein VV1584
           - Vibrio vulnificus (strain YJ016)
          Length = 259

 Score =  146 bits (354), Expect = 6e-34
 Identities = 80/218 (36%), Positives = 116/218 (53%), Gaps = 9/218 (4%)

Query: 65  TLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKA 124
           T  +P+     +  +GLNY DH  E    PP+ P +F K  +T+           D+ + 
Sbjct: 37  TWLSPIENPGTIFALGLNYADHASELAFEPPKEPLVFLKGANTLTAHQQPSYRPNDI-EF 95

Query: 125 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 184
           +  E EL  V+GK+A  V    A DY+ G+TI  D    D+ +N     L + K+ D+ C
Sbjct: 96  MHYECELVAVVGKEARNVKREDAMDYIQGFTICNDYAIRDYLENYYRPNLRV-KSRDSLC 154

Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244
           PIGPWIV  D+I +  NL +   +NG   Q+ NT+  I  +P +I  LS+ MTL PGD+I
Sbjct: 155 PIGPWIVDCDDIEDVNNLALTTHVNGELTQQGNTSDMIFDVPFLIEYLSSFMTLKPGDLI 214

Query: 245 LTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
            TGTP G+       + +QPGDV+   IE +G+ E  V
Sbjct: 215 ATGTPKGL-------KDIQPGDVVRCTIEGVGSLENPV 245


>UniRef50_A3VFY9 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Rhodobacterales bacterium
           HTCC2654|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Rhodobacterales bacterium HTCC2654
          Length = 279

 Score =  146 bits (354), Expect = 6e-34
 Identities = 83/223 (37%), Positives = 118/223 (52%), Gaps = 7/223 (3%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQK----LTPPELPFIFNKFPSTVVGPNDTIK 116
           L+G+T    V    +VLC+GLNYKDH  E K     T P+ P +F +F +++    +++ 
Sbjct: 54  LAGVTYTPVVPDAQQVLCIGLNYKDHRAETKGEVGTTYPDNPIVFMRFATSLAAHGESLP 113

Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176
           +   VS+ V  E EL V+IGK    +  + A  +V GY    DI   DW+   K  Q   
Sbjct: 114 IPK-VSEVVDYEAELAVIIGKGGRYIAKADAMSHVAGYAPFNDISMRDWQM--KGEQWGP 170

Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236
           GK      P GP +VT DE+G+     ++  ++G   Q+S     I  IP +I+  SN +
Sbjct: 171 GKNFPKSGPFGPVMVTPDEVGDLGETGIRLILDGEVLQESWIKHLIFDIPTLISYCSNFV 230

Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFE 279
            L PGD+I+TGTPGGVG  R PP  L PG     E++ IG  E
Sbjct: 231 ELRPGDVIVTGTPGGVGFVRKPPILLAPGKTCVVEVDGIGRLE 273


>UniRef50_Q66BX8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase / 5-carboxymeth..; n=42; Bacteria|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase /
           5-carboxymeth.. - Yersinia pseudotuberculosis
          Length = 254

 Score =  146 bits (353), Expect = 7e-34
 Identities = 81/207 (39%), Positives = 114/207 (55%), Gaps = 9/207 (4%)

Query: 76  VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 135
           +  +GLNY DH  E   +PP+ P IF K P +  G    + ++ D  + +  E EL VV+
Sbjct: 46  LFALGLNYVDHAAELDFSPPKEPLIFIKAPHSFTGHRQ-VSVRPDNIEYMHYEAELVVVV 104

Query: 136 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE 195
           GK A  ++ +HA DYV GYT+  D    D+ +N     L + K+ DT  PIGPWIV   +
Sbjct: 105 GKPARYLNPAHAMDYVAGYTLCNDYAVRDYLENYYRPNLRV-KSRDTLTPIGPWIVDKAD 163

Query: 196 IGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVY 255
           I NP NL ++  +NG   Q+ NT   I  IP ++A LS  +TL PGD+I TGTP G+   
Sbjct: 164 IPNPHNLVIRTWVNGELCQRGNTADLIFDIPFLMAYLSEFITLQPGDMIATGTPKGL--- 220

Query: 256 RNPPEFLQPGDVITSEIENIGTFETRV 282
                 + PGD +  E++ IG    RV
Sbjct: 221 ----SNVVPGDEVVVEVDGIGCLLNRV 243


>UniRef50_A4SYL9 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Polynucleobacter sp.
           QLW-P1DMWA-1|Rep: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 309

 Score =  145 bits (352), Expect = 1e-33
 Identities = 88/230 (38%), Positives = 122/230 (53%), Gaps = 10/230 (4%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP-----PELPFIFNKFPSTVVGPNDTIKLK 118
           IT   P+   DK LCVG NY+ H EE K T      P+ P  F K  S + G N T+   
Sbjct: 81  ITYLPPIMDADKFLCVGKNYRTHLEELKRTNLIKEIPQEPTSFIKLNSCLSGHNATVVRP 140

Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLL 176
             ++K +  E EL  V+GK+A     S A DY+ G TI  D+   D +  +  S  +   
Sbjct: 141 KGITK-LDYEPELVFVMGKRALGAKKSEAMDYIGGVTILNDLTCRDLQLREVASGSRFWT 199

Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236
           GK +  F P+GP I+T DEI NP +L + CS+NG ++ + NT   I KI DI+   S  +
Sbjct: 200 GKNIPGFGPLGPEIITIDEIPNPYDLWMTCSVNGEERMRVNTQDQIWKISDILEHFSRFI 259

Query: 237 TLLPGDIILTGTPGGVGVYRNPPE--FLQPGDVITSEIENIGTFETRVEE 284
            +  GD+  TG PGGV V +   E  +L+PGDV+   I+ I T  T + E
Sbjct: 260 PIEAGDMFSTGAPGGVAVGKENAEALYLKPGDVVECAIDGISTLRTTIAE 309


>UniRef50_Q1MQ53 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Lawsonia intracellularis PHE/MN1-00|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Lawsonia intracellularis (strain
           PHE/MN1-00)
          Length = 257

 Score =  145 bits (351), Expect = 1e-33
 Identities = 82/217 (37%), Positives = 122/217 (56%), Gaps = 12/217 (5%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128
           P+    K++C+ +NY +  +E +   P  P  F K PS++VG    I L  ++ + VV E
Sbjct: 45  PLVSPTKIICIDINYHEKAQELQQPIPTNPTFFFKPPSSIVGNGQPILLPTNIGR-VVSE 103

Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188
            EL +VIG+   KV    A +Y+ GYT A DI A D ++ +  +     KA +TFCP+GP
Sbjct: 104 AELCIVIGQTCYKVTPEAASNYIFGYTCANDITAKDIQQQEYTTSH--AKAYNTFCPVGP 161

Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248
           WI T  ++ N +NL ++ SIN    Q S T   I    ++I+ LSN+MTL PGD+ILTGT
Sbjct: 162 WIET--DVPNIENLQIRNSINSELGQVSTTADMIFPPLELISFLSNIMTLNPGDLILTGT 219

Query: 249 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285
           P G          +  GD++ + IEN+G     +EE+
Sbjct: 220 PKG-------SLLISDGDIVQTSIENVGILINPIEEY 249


>UniRef50_Q46NJ4 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=6; Proteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 292

 Score =  144 bits (350), Expect = 2e-33
 Identities = 95/294 (32%), Positives = 140/294 (47%), Gaps = 13/294 (4%)

Query: 1   MKLLQFSYKNSD--GIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXX 58
           MKL+ F   +S   G   G      VVD+++  P +PS    LL                
Sbjct: 1   MKLVTFRTSDSVSWGAVVGHDSASGVVDLSRRLPDVPSVK-SLLSGGASLLARAREALAG 59

Query: 59  XX----LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP--PELPFIFNKFPSTVVGPN 112
                 LS + L  PV G +K+ C+G+NY     E K     P+ P +F + P+++ G  
Sbjct: 60  VQVDHPLSSVQLLPPVLGPEKIFCIGVNYAHRNAEYKDNSDLPKYPSVFMRTPASLTGHG 119

Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS 172
             + L  + SK +  E E+ +VIGK   ++    A  ++ G T   +    DW  + K +
Sbjct: 120 QPLLLPPE-SKQLDYEGEIGIVIGKAGRRIAKEDAHTHIAGLTCINEGTIRDWLHHGKFN 178

Query: 173 QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 232
            +  GK  D    IGPWIVT+DE  +  N+ +   +NG  +Q+  T   +     +I+ L
Sbjct: 179 -VTQGKNFDASGAIGPWIVTADEFPDFDNIGLTTRVNGEVRQQDTTANLMFPFASLISYL 237

Query: 233 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFE--TRVEE 284
           S   TL PGDII TGTP G GV  +PP FL PGDV+  E++ +G      R EE
Sbjct: 238 SQFATLNPGDIIATGTPIGAGVRFDPPRFLVPGDVVEVEVDGVGVLANVVRAEE 291


>UniRef50_Q0C030 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Hyphomonas neptunium ATCC 15444|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Hyphomonas neptunium (strain ATCC 15444)
          Length = 281

 Score =  144 bits (350), Expect = 2e-33
 Identities = 81/222 (36%), Positives = 118/222 (53%), Gaps = 5/222 (2%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L  + L  P     K++C+GLNYK+H +E     P  P +F K   ++V P+    L+  
Sbjct: 61  LDQVGLLMPSEPLSKLVCLGLNYKNHVDETHNDLPPNPALFTKVADSLV-PHGEAVLRPK 119

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           VS+    E E+ VVIGK    +    A D+V GYTI  D    D++K+     +  GK  
Sbjct: 120 VSEQFDYEGEICVVIGKGGRHISRETALDHVFGYTIMLDGSVRDYQKHS----VSAGKNF 175

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
                +GPWIVT+DEI +P  + ++  +NG   Q +  +  ++ IP  IA +S    L P
Sbjct: 176 WRSGALGPWIVTADEIPDPSVMKLETRLNGETVQSTTADLMLYDIPTAIAYVSQWTPLAP 235

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GD+I TGTPGGVG  R PP +++ GDVI  ++  IG     V
Sbjct: 236 GDVIATGTPGGVGARRKPPLWMKAGDVIEVDVSQIGVLSNPV 277


>UniRef50_Q0LC36 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Herpetosiphon aurantiacus ATCC
           23779|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Herpetosiphon aurantiacus ATCC 23779
          Length = 293

 Score =  144 bits (349), Expect = 2e-33
 Identities = 76/175 (43%), Positives = 100/175 (57%), Gaps = 8/175 (4%)

Query: 76  VLCVGLNYKDHCEEQ------KLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 129
           V CVGLNY  H  E       ++  PE P  F K P+ +  P   I +   VS+ +  E+
Sbjct: 76  VFCVGLNYAAHARESLQAKGLEVKMPEHPVFFTKPPTAINSPTGEIVIDPAVSERIDWEV 135

Query: 130 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 189
           EL VVIGK    +    A ++V GYT+  D+ A D +   +  Q   GKA+D  CP+GPW
Sbjct: 136 ELGVVIGKAGKNISHEQAMEHVWGYTVINDVSARDLQMRHQ--QFFKGKALDGSCPMGPW 193

Query: 190 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244
           I+TSDE+ +P NL V+  +NG  KQ+SNTN  I  IP +I  LS  MTL PGDII
Sbjct: 194 IITSDELTDPHNLVVRLRVNGEIKQESNTNDLIFNIPTLIHVLSQGMTLEPGDII 248


>UniRef50_A3LSP4 Cluster: Degradation of aromatic compounds; n=9;
           Ascomycota|Rep: Degradation of aromatic compounds -
           Pichia stipitis (Yeast)
          Length = 293

 Score =  144 bits (349), Expect = 2e-33
 Identities = 78/225 (34%), Positives = 119/225 (52%), Gaps = 7/225 (3%)

Query: 65  TLKAPVHGND--KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122
           TL  P+  +D   V CVGLN+  H +E   TPP  P IF K   +V    + I +     
Sbjct: 66  TLLGPLTPDDVPMVKCVGLNFMKHIQEGGRTPPPFPSIFYKTSFSVADFGEDIPIPKIAQ 125

Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK----ISQLLLGK 178
                E EL +VIGK    +    A  YV GY    D+ + +W+K+ +    + Q    K
Sbjct: 126 SKCDYEGELCIVIGKTGKNIKEEEALSYVAGYVTGNDVSSRNWQKDPEFAGSVPQWCFSK 185

Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTL 238
           + D + P+GP +V+   I NP NL+++ ++NG  +Q +NT+  +  +P II+ +S   TL
Sbjct: 186 SFDKYAPLGPALVSPQVIQNPGNLSLQTTVNGEIRQDANTDDLLFGVPRIISFISQSTTL 245

Query: 239 LPGDIILTGTPGGVGVYRNP-PEFLQPGDVITSEIENIGTFETRV 282
             G +I+TGTP GV +   P P +LQ GDV+   I+ IGT   ++
Sbjct: 246 EMGTVIMTGTPSGVALGMKPTPVYLQNGDVVEVAIDQIGTLSNKM 290


>UniRef50_Q9RYT2 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase; n=4; Deinococci|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase - Deinococcus radiodurans
          Length = 262

 Score =  144 bits (348), Expect = 3e-33
 Identities = 81/208 (38%), Positives = 119/208 (57%), Gaps = 9/208 (4%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           KV+ + LNY DH  E     PE P +F K P+T + P+    +    +K +  E+EL +V
Sbjct: 46  KVIALALNYADHVAELGFKAPEEPVMFLK-PNTSLLPHQGTVIYPRGAKFMHYEVELGIV 104

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IG+ A +V +  A DYV GYTIA D+   D+  N      +  K  DTF P+GP++V++D
Sbjct: 105 IGRDARRVKAKDADDYVGGYTIANDLVVRDYVSNY-YRPPMRAKGWDTFGPLGPYLVSAD 163

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           E+ +P NL ++  +NG  +Q+ +T   I K P++I  +S  MTL  GD+ILTGTP GV  
Sbjct: 164 EVPDPYNLGLRAYVNGELRQEGSTRDMILKAPELIEFMSRFMTLEAGDVILTGTPKGV-- 221

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282
                  + PGDV+  EI+ +G  E  V
Sbjct: 222 -----SHVHPGDVMRLEIDGLGALENPV 244


>UniRef50_Q1M9K7 Cluster: Putative FAA hydrolase family protein;
           n=1; Rhizobium leguminosarum bv. viciae 3841|Rep:
           Putative FAA hydrolase family protein - Rhizobium
           leguminosarum bv. viciae (strain 3841)
          Length = 282

 Score =  144 bits (348), Expect = 3e-33
 Identities = 82/189 (43%), Positives = 107/189 (56%), Gaps = 14/189 (7%)

Query: 76  VLCVGLNYKDHCEEQKLTP-----------PELPFIFNKFPSTVVGPNDTIKLKMDVSKA 124
           V CVG NY  H  E   +            PE P IF K  S++  P   I L   + +A
Sbjct: 87  VFCVGKNYHAHAHEFTKSGFDAGATAAEAIPEHPIIFTKPSSSLARPFGDIPLWPGLDEA 146

Query: 125 VVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFC 184
           V  E EL VVIGK    + +  A D+V GYT+  D+ A D +K  K  Q  LGK +D F 
Sbjct: 147 VDYEAELAVVIGKAGRFITAERALDHVFGYTVFNDVTARDLQKKHK--QWFLGKGIDGFG 204

Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244
           PIGPWIVT DE+ +  N+ + C++NG ++QK++T   I  IP +I  +S  +TLLPGDII
Sbjct: 205 PIGPWIVTKDEL-DIANVEITCTVNGEERQKTSTKDLIFDIPTLIEVISRSVTLLPGDII 263

Query: 245 LTGTPGGVG 253
            TGTP GVG
Sbjct: 264 ATGTPAGVG 272


>UniRef50_A2W1T8 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=9; Proteobacteria|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Burkholderia cenocepacia PC184
          Length = 306

 Score =  143 bits (347), Expect = 4e-33
 Identities = 78/223 (34%), Positives = 119/223 (53%), Gaps = 4/223 (1%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L  + +  P    +K+LCVGLNY DH  E        P +F +F S+++G +  I L   
Sbjct: 77  LDAVRVLPPFGRPNKILCVGLNYLDHSMETGFAKQTYPTVFARFASSLIGHDQPIALPAQ 136

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
            S+ +  E EL  VIGK    +    A D+V GY++  D+   D++   +  Q  +GK  
Sbjct: 137 SSQ-LDYEGELVAVIGKAGRGITRERALDHVAGYSLFNDVTLRDYQF--RTPQWTMGKNF 193

Query: 181 DTFCPIGPWIVTSDEIGNP-QNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
           D     GPW VT+DE+    + L ++  +NG   Q+++T+  I  I  ++  LS VMTL 
Sbjct: 194 DGTGGFGPWFVTADELPRGCKGLRIQTRLNGAVVQEASTSDMIFDIETLVVMLSEVMTLQ 253

Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
            GD+I+TGTP G+G+ R P  +++ GDV   EIE +G     V
Sbjct: 254 AGDLIVTGTPAGIGMAREPQLWMKAGDVCEVEIEQLGVLRNAV 296


>UniRef50_A3YEW7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Proteobacteria|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Marinomonas sp. MED121
          Length = 298

 Score =  143 bits (346), Expect = 5e-33
 Identities = 84/260 (32%), Positives = 133/260 (51%), Gaps = 5/260 (1%)

Query: 19  LDGDNVVDINKEDPKLPSTLIELLKT-NXXXXXXXXXXXXXXXLSGITLKAPVHGNDKVL 77
           + G+  ++I+ +D +  S L +++                   +S I    P+    KV+
Sbjct: 25  IQGELAINISSQDNQFGSDLSQIINNPQLLEKISGYSSAPGIPVSQIQPSLPLQHPGKVI 84

Query: 78  CVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGK 137
           C+GLNY DH +E     P+ P +F +  S+++ P     ++  VS  +  E EL +++GK
Sbjct: 85  CLGLNYMDHIKEGGYKVPDYPALFMRSHSSLM-PAQAPMVRPKVSVQLDYEAELMLIVGK 143

Query: 138 KASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIG 197
               +  S A DYV GYTI  D    D+++  K  Q   GK  D    IGP IVT DE+ 
Sbjct: 144 HGRHIPESKALDYVFGYTIFNDGSVRDYQR--KTHQWTPGKNFDNTGAIGPIIVTPDELP 201

Query: 198 N-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYR 256
                L ++  +     Q +NT++ +  +  +IA +S+  TL PGD+I  GTP GVG  R
Sbjct: 202 EGAHGLKIETRVGDEILQSANTSEMLWSVARVIAEISSYTTLEPGDLIAMGTPPGVGHAR 261

Query: 257 NPPEFLQPGDVITSEIENIG 276
           +P  +L+PG+V+  EIE IG
Sbjct: 262 SPARWLEPGEVVEVEIEGIG 281


>UniRef50_Q13HB6 Cluster: Putative fumarylacetoacetate (FAA)
           hydrolase; n=1; Burkholderia xenovorans LB400|Rep:
           Putative fumarylacetoacetate (FAA) hydrolase -
           Burkholderia xenovorans (strain LB400)
          Length = 257

 Score =  142 bits (345), Expect = 7e-33
 Identities = 79/204 (38%), Positives = 113/204 (55%), Gaps = 12/204 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           ++  VG+NY  H  E     P +P  F    +  +GP + I ++   ++ V  E EL +V
Sbjct: 55  RLFAVGMNYVGHIAEAGAKTPVIPQFFMMPTTAAIGPGEAI-VRPREAQVVHHEAELAIV 113

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK-ISQLLLGKAMDTFCPIGPWIVTS 193
           IG++  ++D   A D+V GYT A D+     +  +     LL+GKA DTFCP+GP I T 
Sbjct: 114 IGRRGRRIDVERALDHVFGYTCANDVSERVIQNREMGYGCLLVGKAFDTFCPLGPVIATG 173

Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
            + GN   L V+ S+NG  +Q  NT+  +  +P I++ LS  +TLLPGD+ILTGTP GVG
Sbjct: 174 LDAGN---LRVRASVNGSPRQDGNTSDLLFTVPHIVSYLSQAVTLLPGDVILTGTPSGVG 230

Query: 254 VYRNPPEFLQPGDVITSEIENIGT 277
                   L  GDV    I+ IGT
Sbjct: 231 P-------LLSGDVCEITIDGIGT 247


>UniRef50_Q5KJF0 Cluster: Mitochondrion protein, putative; n=1;
           Filobasidiella neoformans|Rep: Mitochondrion protein,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 336

 Score =  142 bits (345), Expect = 7e-33
 Identities = 94/287 (32%), Positives = 153/287 (53%), Gaps = 12/287 (4%)

Query: 1   MKLLQF-SYKNSDGIRAGFLDGDN--VVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXX 57
           MK + + S  +  GI  G +D     V  ++  D  L  T+ +L++              
Sbjct: 18  MKFVSYRSRLHPQGI-VGLVDSTEQFVAPLSFPDNTLVRTMQQLIEEWDATHRHLLHGAP 76

Query: 58  XXXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPF--IFNKFPSTVVGPNDTI 115
              L  + + AP+ G D V+CVG NY++H E  +     + +  IF K  ++++G N  I
Sbjct: 77  MESLDIVEILAPLRGRD-VICVGKNYREHAEWVRSLFKLVKYVVIFTKRATSIIGTNQEI 135

Query: 116 KLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL 175
                V++ +  E EL ++IGK   ++    A+DYV G TI  D+ A + +++ K  Q  
Sbjct: 136 YPHPRVTQTLDYEGELGIIIGKAGIQISREDAWDYVWGATIINDVTARERQRDHK--QFY 193

Query: 176 LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNV 235
           +GK++DTFCP+GP+ V S  + + +N+ ++  +NG  +Q +NT+Q I  IP +IA  S  
Sbjct: 194 IGKSLDTFCPMGPYAVHSSVL-DWRNMMLETRVNGQIRQSANTSQLIFDIPALIATCSMG 252

Query: 236 MTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           +TL PGD+I TGTP GV +  +  EFL+  DVI   +  +GT    V
Sbjct: 253 ITLQPGDVISTGTPAGVCL--SSGEFLKHRDVIDISMSGLGTLSNTV 297


>UniRef50_A0LGT2 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Syntrophobacter fumaroxidans
           MPOB|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 235

 Score =  141 bits (342), Expect = 2e-32
 Identities = 83/224 (37%), Positives = 117/224 (52%), Gaps = 22/224 (9%)

Query: 75  KVLCVGLNYKDHCEEQKLTP--------PELPFIFNKFPSTVVGPNDTIKLKMDVSK--- 123
           K++ +GLNY+ H  E             PE P +F K P+ ++GP ++I +   + +   
Sbjct: 19  KIIALGLNYRAHIAESTTVKVRGFTDEVPEEPILFPKTPNVLIGPGESIVIPAFLKEYGF 78

Query: 124 ---AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
                  E EL V+I  +   V    A  +V GYT   D+   + +   +      GK++
Sbjct: 79  PEPRTDYEAELAVIIKDECKNVGPGDALKHVFGYTCMNDVSQRNLQTGDRAGWFR-GKSL 137

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           DTF PIGP IV  D++G+P NL + C +NGV  Q SNT   I KIP+IIA +S    L+P
Sbjct: 138 DTFGPIGPVIVRPDDLGDPHNLRICCRLNGVTVQDSNTGSMIFKIPEIIAFVSRNFKLMP 197

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           GD+I+TGTP GVG  R+       GDV+  EIE IG     V E
Sbjct: 198 GDVIVTGTPSGVGPIRH-------GDVVEVEIEKIGILRNPVVE 234


>UniRef50_A0K0J6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=5; Actinomycetales|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Arthrobacter sp. (strain FB24)
          Length = 290

 Score =  141 bits (342), Expect = 2e-32
 Identities = 79/214 (36%), Positives = 119/214 (55%), Gaps = 4/214 (1%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           + L AP+     V+ +GLNY  H  E     PE+P +F K  +TV GP D   +   +S+
Sbjct: 68  LRLGAPLSRPGAVVGIGLNYAGHAAESGAAVPEVPVVFLKPSNTVAGPFDDAPIP-PLSR 126

Query: 124 AVVCEIELTVVIGKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDT 182
               E+EL VVIG++AS + S   A   V GY +A D+   D++      Q + GK++  
Sbjct: 127 KYDWEVELAVVIGQRASYLKSVDEAAGCVAGYVLANDLSERDYQLPGAAGQWVKGKSLPA 186

Query: 183 FCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGD 242
             P+GPW V + ++ +P  L ++  +NG  +Q S+T   I  +P ++  LS  M L PGD
Sbjct: 187 STPLGPWFVPAADL-DPSALRLRTWVNGELRQDSSTADLIFDVPAVVHHLSQFMVLEPGD 245

Query: 243 IILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
           +ILTGTP GV +    P +LQ GDV+  E+E +G
Sbjct: 246 VILTGTPEGVALSGRFP-YLQDGDVLELEVEGLG 278


>UniRef50_Q5V4M0 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate
           isomerase; n=4; Halobacteriaceae|Rep:
           2-hydroxyhepta-24-diene-1,7-dioate isomerase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 257

 Score =  141 bits (342), Expect = 2e-32
 Identities = 77/209 (36%), Positives = 115/209 (55%), Gaps = 12/209 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           KV+C+G NY DH EE     P+ P +F K P+ V      + +     + +  E EL VV
Sbjct: 59  KVVCIGRNYADHAEEMDSELPDRPMLFLKAPNAVASHGKHLTMPSGKER-IDYEAELGVV 117

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IG++   V  S A D V GYT   DI   D ++ ++    + GKA D  CPIGP + T +
Sbjct: 118 IGEQCRNVSESGAMDVVAGYTCVNDISNRDDQRREQ--NWVRGKAFDNACPIGPLVATPE 175

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
            +  P++ +++  +NG  KQ S+    I  +P++IA +++ MTL PGD+I TGTP GVG 
Sbjct: 176 HV--PEDASIELRLNGETKQSSSREHLIFSVPELIAEITSYMTLEPGDVIATGTPEGVGP 233

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRVE 283
                  ++ GD +  EIE IGT +  V+
Sbjct: 234 -------MEDGDEVEVEIEGIGTLKHSVK 255


>UniRef50_A3KJW3 Cluster: Putative maleylpyruvate isomerase; n=1;
           Streptomyces ambofaciens ATCC 23877|Rep: Putative
           maleylpyruvate isomerase - Streptomyces ambofaciens ATCC
           23877
          Length = 288

 Score =  141 bits (341), Expect = 2e-32
 Identities = 93/277 (33%), Positives = 139/277 (50%), Gaps = 22/277 (7%)

Query: 15  RAGFLDGDNVVDINKE----DPKLPSTLIE-LLKTNXXXXXXXXXXXXX--XXLSGITLK 67
           R G +DGD++VD+  +        P+  ++  ++T                  L+   L+
Sbjct: 10  RLGVVDGDDLVDVTDQLTGAGTAGPAGAVQRYIETTARGEAVRFDLAGRPRTPLAEAALQ 69

Query: 68  APVHGNDKVLCVGLNYKDHCEEQKLTPPELPF-IFNKFPSTVVGPNDTIKLKMDVSKAVV 126
           AP+    K++   +NY DH  E + T       +F K  S+V+GP + I L     K   
Sbjct: 70  APLPLPGKIIGAPVNYLDHKAEMEYTTSVADLGVFLKANSSVIGPGEDILLPYS-DKRTD 128

Query: 127 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPI 186
            E EL VVIG+ A+ V +  A  +V GYT   DI     E           K+ DTF P+
Sbjct: 129 QEGELGVVIGRTAAHVSADDALGHVFGYTCVLDITVRSGEDRST------RKSFDTFTPL 182

Query: 187 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 246
           GPW+VT+DEI +P  L+++C + G  +Q++NT   I  + ++IA  S+VMTL PGD+I T
Sbjct: 183 GPWVVTADEIPDPDTLDLRCDVGGTTRQRTNTADLIFGVRELIAYTSSVMTLHPGDVIAT 242

Query: 247 GTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           GTP GVG        L  GD +  +IE +G  E  V+
Sbjct: 243 GTPAGVGP-------LAHGDRVVLDIEKVGRLEVGVD 272


>UniRef50_A5FQA8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=3; Dehalococcoides|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Dehalococcoides sp. BAV1
          Length = 253

 Score =  140 bits (339), Expect = 4e-32
 Identities = 79/179 (44%), Positives = 105/179 (58%), Gaps = 6/179 (3%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++ +GLNYK H  E     P+LP IF K  S ++GP D I +K   S+ V  E EL V+
Sbjct: 56  KIIAIGLNYKAHAGEMAEDLPKLPLIFFKNASGIIGPEDNI-IKPGQSERVDYEGELAVI 114

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           I KK   +    AFDY+LGY+   D+ A D +K     Q    K  DTF   GPWI T  
Sbjct: 115 IRKKTRNIKPEDAFDYILGYSCFNDVTARDLQKID--GQWSRAKGFDTFAVCGPWIET-- 170

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
           E+ +PQ   ++  +NG  KQ+++T   I  IP I++ +S VMTLLPGDII TGTP G+G
Sbjct: 171 EL-DPQVQLLETYLNGKLKQRTSTADMIFSIPRIVSFISEVMTLLPGDIIATGTPSGIG 228


>UniRef50_A6NUP5 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 250

 Score =  140 bits (338), Expect = 5e-32
 Identities = 80/208 (38%), Positives = 115/208 (55%), Gaps = 13/208 (6%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++CVG NY DH  E     P+ P +F K P+TV  P   +    D  + +  E EL  V
Sbjct: 55  KIICVGKNYYDHAMEMGEGVPDRPILFIKAPNTVNHPEGEVSAP-DFVERLDYEGELAFV 113

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           + K+A  V +    DY+LGYT   D+ A D +K+    Q   GK+MD F PIGP +  +D
Sbjct: 114 VKKRAKNVKAEEYGDYILGYTCLNDVTARDIQKSD--GQWSRGKSMDGFAPIGPLV--TD 169

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           E+    +L ++  +NG   Q S T+ F+ KIP ++  ++  MTL PGD++ TGTP G+G 
Sbjct: 170 EVDG-SDLKIETRLNGKTVQSSRTSLFMTKIPALMEFITASMTLEPGDVVTTGTPAGIGA 228

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282
                  +QPGDV+  EIE IGT    +
Sbjct: 229 -------MQPGDVVEVEIEGIGTLRNYI 249


>UniRef50_Q46978 Cluster: 4-hydroxyphenylacetate degradation
           bifunctional isomerase/decarboxylase [Includes:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC
           5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2-
           hydroxymuconate Delta-isomerase);
           5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate
           decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5-
           tricarboxylate decarboxylase) (OPET decarboxylase)];
           n=42; Proteobacteria|Rep: 4-hydroxyphenylacetate
           degradation bifunctional isomerase/decarboxylase
           [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
           (EC 5.3.3.10) (HHDD isomerase) (5-carboxymethyl-2-
           hydroxymuconate Delta-isomerase);
           5-carboxymethyl-2-oxo-hex-3-ene-1,7- dioate
           decarboxylase (EC 4.1.1.68) (5-oxopent-3-ene-1,2,5-
           tricarboxylate decarboxylase) (OPET decarboxylase)] -
           Escherichia coli
          Length = 429

 Score =  139 bits (337), Expect = 6e-32
 Identities = 78/212 (36%), Positives = 114/212 (53%), Gaps = 9/212 (4%)

Query: 71  HGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIE 130
           H +  +  +GLNY DH  E +  PPE P +F K P+T+ G N T  ++ +  + +  E E
Sbjct: 220 HPHGTLFALGLNYADHASELEFKPPEEPLVFLKAPNTLTGDNQT-SVRPNNIEYMHYEAE 278

Query: 131 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWI 190
           L VVIGK+A  V  + A DYV GYT+  D    D+ +N     L + K+ D   P+   I
Sbjct: 279 LVVVIGKQARNVSEADAMDYVAGYTVCNDYAIRDYLENYYRPNLRV-KSRDGLTPMLSTI 337

Query: 191 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 250
           V  + I +P NL ++  +NG  +Q+  T   I  +P +IA LS  MTL PGD+I TGTP 
Sbjct: 338 VPKEAIPDPHNLTLRTFVNGELRQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIATGTPK 397

Query: 251 GVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           G+         + PGD +  E+E +G    R+
Sbjct: 398 GL-------SDVVPGDEVVVEVEGVGRLVNRI 422



 Score = 74.5 bits (175), Expect = 3e-12
 Identities = 48/156 (30%), Positives = 70/156 (44%), Gaps = 9/156 (5%)

Query: 94  PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 153
           PP+    F K  +TV+G  + I       + V+    + +++GK A+KV    A +Y+ G
Sbjct: 31  PPKTAVWFIKPRNTVIGCGEPIPFPQ--GEKVLSGATVALIVGKTATKVREEDAAEYIAG 88

Query: 154 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213
           Y +A D+   +          +  K  D FCPIG  +  S    N  NL +   ING   
Sbjct: 89  YALANDVSLPE---ESFYRPAIKAKCRDGFCPIGETVALS----NVDNLTIYTEINGRPA 141

Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 249
              NT         +++ LS   TL PGD IL GTP
Sbjct: 142 DHWNTADLQRNAAQLLSALSEFATLNPGDAILLGTP 177


>UniRef50_Q313F7 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=3; Desulfovibrio|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Desulfovibrio desulfuricans (strain G20)
          Length = 264

 Score =  139 bits (336), Expect = 9e-32
 Identities = 80/208 (38%), Positives = 113/208 (54%), Gaps = 12/208 (5%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128
           PV    K++CVG+N++DH EE     PE P  F K  S V+G    + L  + S  V  E
Sbjct: 44  PVVTPSKIVCVGMNFRDHAEEIGFPVPEEPVFFLKPSSAVIGSGQPVVLPAE-SGRVEHE 102

Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188
            EL VVIG+ A  +       +V GYT A D+ A D +    +      K  DTF P+GP
Sbjct: 103 AELGVVIGRAARNITPEDVPAHVFGYTCANDVTARDLQSRDGLFGRC--KGFDTFAPVGP 160

Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248
           WI T  E+ +  +L ++  +NG  +Q+ +T   +    +I+A +S VMTLLPGD+ILTGT
Sbjct: 161 WIET--EVPDLSSLGIRAMVNGELRQQGSTADMLFSPHEIVAAVSRVMTLLPGDLILTGT 218

Query: 249 PGGVGVYRNPPEFLQPGDVITSEIENIG 276
           P GVG        L+ GD +  EI+ +G
Sbjct: 219 PAGVGP-------LEDGDEVRVEIDGVG 239


>UniRef50_A3YN46 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=13; Campylobacter|Rep: Fumarylacetoacetate
           hydrolase family protein - Campylobacter jejuni subsp.
           jejuni CF93-6
          Length = 292

 Score =  139 bits (336), Expect = 9e-32
 Identities = 77/214 (35%), Positives = 115/214 (53%), Gaps = 8/214 (3%)

Query: 76  VLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEI 129
           ++C+G+N+ DH +E      +K    E P  F K  +    P  +I L  DV+  +  E 
Sbjct: 77  IICLGINFLDHAKESAQFKGEKFEEREYPVYFGKRCNQATAPFGSISLHADVTSQLDYEC 136

Query: 130 ELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPW 189
           EL  ++ K A K+ +  A DY+ GYTI  +I A D +K  K  Q    K+++    +GP+
Sbjct: 137 ELAFILSKDAYKIKAEDAKDYIFGYTIINEISARDLQKRHK--QFYRAKSLEGSTIMGPY 194

Query: 190 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 249
           I + DEI  P  L++K  +N   +Q SNT  FI  I  ++  LS+ M L  G II  GTP
Sbjct: 195 ITSVDEIAYPPELHLKSYVNKELRQNSNTKFFIFDIGYVLEELSSGMLLKAGTIISMGTP 254

Query: 250 GGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
            GVG+  NPP FL+ GD +   IEN+G    +++
Sbjct: 255 SGVGMGLNPPVFLKKGDEVRCVIENLGELCNKIK 288


>UniRef50_Q8YDN8 Cluster: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE
           ISOMERASE / 5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE
           DECARBOXYLASE; n=19; Proteobacteria|Rep:
           2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE /
           5-CARBOXYMETHYL-2-OXO- HEX-3-ENE-1,7-DIOATE
           DECARBOXYLASE - Brucella melitensis
          Length = 311

 Score =  138 bits (334), Expect = 1e-31
 Identities = 81/282 (28%), Positives = 133/282 (47%), Gaps = 6/282 (2%)

Query: 7   SYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX--LSGI 64
           S+    G   G L  D +VD++        TL E+++                   LS I
Sbjct: 29  SFSTCGGRHYGVLKEDGIVDLSARHGSRWPTLREVIEAGVLAQLAQEAAGLAADVPLSSI 88

Query: 65  TLKAPVHGNDKVLCVGLNYKDHCEEQK--LTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122
           T + P+    K++CVG+N+ D  EE K     P  P +F +FP +  G    + ++   S
Sbjct: 89  TYEIPIPSPGKIICVGVNFPDRNEEYKDGQAAPANPSLFVRFPRSFTGHERPL-MRPPES 147

Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDT 182
             +  E E+ +VIGK   ++    A D++   T+  +    DW ++ K + +  GK  D 
Sbjct: 148 PQLDYEGEIAIVIGKGGRRIAEKDALDHIAALTLCNEGTIRDWVRHAKFN-VTQGKNFDA 206

Query: 183 FCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGD 242
              IGPW+V   +     ++ +   +NG  +Q+  T++ I     II  +S   TL+PGD
Sbjct: 207 TGSIGPWLVPYTDESQIADIQLTTRVNGEVRQQDRTSRMIFSFRKIINYVSTFTTLVPGD 266

Query: 243 IILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           +I+ GTP G G   +PP +L+PGDV+  E E IG     + +
Sbjct: 267 VIVCGTPTGAGARFDPPIWLKPGDVVEVEAEGIGLLRNTIAD 308


>UniRef50_Q1IVB8 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Acidobacteria bacterium
           Ellin345|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 263

 Score =  137 bits (332), Expect = 3e-31
 Identities = 78/211 (36%), Positives = 111/211 (52%), Gaps = 12/211 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++CVG NYK H EE     P+ P IF+K  S ++ P   IK    +S+ V  E EL V+
Sbjct: 63  KIVCVGRNYKAHAEELGHEIPKYPLIFSKPTSAIIAPGADIKRPAKLSQRVDYEGELGVI 122

Query: 135 IGKKASKVDSSH-AFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193
           IG++   +   H    Y+ GYT+  D+ A D +   K  Q    K  DTFCP+GP  + +
Sbjct: 123 IGRECRHIPEDHDVRSYIHGYTVVNDVTARDLQ--NKDGQWTRAKGFDTFCPVGP--IVN 178

Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
           D +     + V+  +NG  +Q  NT+ FI  +  I+  +S VMTL PGD+I TGTP GVG
Sbjct: 179 DALDPWTGVEVETRVNGAVRQHGNTSSFIFPLDVILRFISEVMTLFPGDLIATGTPEGVG 238

Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
                   +  GDV+   +  IGT    V +
Sbjct: 239 P-------IIAGDVVEVSVAGIGTLRNPVAD 262


>UniRef50_Q0S9S7 Cluster: Possible fumarylacetoacetate hydrolase;
           n=2; Actinomycetales|Rep: Possible fumarylacetoacetate
           hydrolase - Rhodococcus sp. (strain RHA1)
          Length = 281

 Score =  137 bits (332), Expect = 3e-31
 Identities = 84/222 (37%), Positives = 119/222 (53%), Gaps = 9/222 (4%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKF-PSTVVGPNDTIKLKMDVS 122
           +++  PV  + +V+CVGLNYK H  E   TPP  P +F ++ PS  V   D     +  +
Sbjct: 57  VSVVPPVPDSARVICVGLNYKAHAAEGGFTPPPYPTLFGRWTPSLSV---DGAPTPVPAN 113

Query: 123 KAVV-CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMD 181
           +A +  E E+   IG +   VD++     VLGY    D+ A   +  K  +Q  LGK  D
Sbjct: 114 EAGLDWEGEVAAFIGTRLESVDAATGQAGVLGYACFNDLTAR--KAQKLTAQWTLGKNGD 171

Query: 182 TFCPIGPWIVTSDEIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
              P+GP +V + E+G+    L V+  +NG   Q  NT   I  + +IIA +S   TL P
Sbjct: 172 RSGPLGP-LVPAGEVGDLSDGLRVQTRVNGTVVQDGNTRDLIFSVGEIIALVSETFTLHP 230

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GDII TGTP GVG  RNPP  L PGD++  EI+ +G   T +
Sbjct: 231 GDIIATGTPEGVGYVRNPPWLLGPGDIVEVEIDKLGVLRTPI 272


>UniRef50_Q46S57 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=4; Burkholderiales|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 284

 Score =  137 bits (331), Expect = 3e-31
 Identities = 75/224 (33%), Positives = 120/224 (53%), Gaps = 4/224 (1%)

Query: 62  SGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV 121
           + +T   PV    K+LCVGLNY DH +E     P+ P +F + P+++VG +D   ++   
Sbjct: 60  AALTWLPPVISPRKILCVGLNYADHTKESPYEQPDYPTLFLRVPTSMVG-HDCAIVRPLA 118

Query: 122 SKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMD 181
           S  +  E EL VVIGK    +    A  +V GY++  D    +++   K  Q  +GK  D
Sbjct: 119 SDTLDYEGELAVVIGKGGKHIAREDALSHVFGYSVFNDGSVREYQF--KSPQWTVGKNFD 176

Query: 182 TFCPIGPWIVTSDEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
                GP++VT+DE+      L ++  +NG   Q ++T+  ++ +  +IA +S  +TL P
Sbjct: 177 ATGGFGPYVVTADELPPGATGLRLETRLNGQVVQSASTSDMLYDVASLIAIISEAITLEP 236

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           GD+I+ GTP G+G  R P   ++ GDV    IE IGT    + +
Sbjct: 237 GDVIVAGTPSGIGWAREPKLLMRHGDVCEVSIERIGTLSNPIAD 280


>UniRef50_Q09C56 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=2; Cystobacterineae|Rep: Fumarylacetoacetate
           hydrolase family protein - Stigmatella aurantiaca
           DW4/3-1
          Length = 257

 Score =  137 bits (331), Expect = 3e-31
 Identities = 83/224 (37%), Positives = 121/224 (54%), Gaps = 16/224 (7%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVV-GPNDTIKLKM 119
           LS +TL  P   + KV+C+G NY+ H EE     P  P +F K PST + GP   I+L  
Sbjct: 46  LSSLTLLVPSEAS-KVVCIGQNYRKHAEEMGKPVPSEPLLFIK-PSTALNGPRSPIRLPK 103

Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA 179
             S+ V  E EL +VIG++    D + A   + G T   D+ A D ++ +   Q    K+
Sbjct: 104 -ASQEVHYEAELGLVIGERLKNADEATAARAIWGLTCINDVTARDIQRREV--QHTRAKS 160

Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
            DTF  +GPW VT     +P +L + C +NG  +Q S T+  +     +++ +S++MTLL
Sbjct: 161 YDTFACVGPWAVTGL---SPADLRILCRVNGQVRQDSRTSDMVFNPAQLVSFISHIMTLL 217

Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           PGD++ TGTP GVG        L  GD++  E+E IGT    VE
Sbjct: 218 PGDLVSTGTPSGVGA-------LAAGDMVEVELEGIGTLANPVE 254


>UniRef50_A5NU93 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Methylobacterium sp. 4-46|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Methylobacterium sp. 4-46
          Length = 288

 Score =  137 bits (331), Expect = 3e-31
 Identities = 73/211 (34%), Positives = 115/211 (54%), Gaps = 4/211 (1%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++C+G NY  H  E    P + P +F +  +++V   + + ++   S     E EL  V
Sbjct: 79  KIICIGRNYAAHAREGGAEPLDYPDVFMRGANSLVAHGEPL-IRPRCSDKFDYEGELVFV 137

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           +G+KA  V    A   + GY++  +    D+++  + +Q  +GK  D     GP +VT D
Sbjct: 138 VGRKARHVGLDEACGIIAGYSVFNEGSIRDYQR--RATQWTMGKNFDGTGGFGPDLVTPD 195

Query: 195 EIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
           E+ +    L +  ++NG   Q  NT+ FI  +  I+A L+  MTL PGD++LTGTP GVG
Sbjct: 196 ELPDGADGLRLTTTLNGHVMQDGNTHDFIFPVARIVAILTEAMTLEPGDVVLTGTPSGVG 255

Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
             RNPP F++PGDV+   IE +GT    V +
Sbjct: 256 YARNPPVFIKPGDVVEVTIEKVGTLRNTVRD 286


>UniRef50_Q8NLC0 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Actinomycetales|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Corynebacterium glutamicum (Brevibacterium flavum)
          Length = 279

 Score =  136 bits (329), Expect = 6e-31
 Identities = 73/220 (33%), Positives = 117/220 (53%), Gaps = 8/220 (3%)

Query: 66  LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAV 125
           L A V    K++CVGLNY +H +E     P+ P +F KFP  ++GP D + +    +KA+
Sbjct: 60  LDAVVPAPKKIVCVGLNYANHIKEMGRDLPDTPTLFVKFPDALIGPFDDVVVPEWANKAL 119

Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTF 183
             E E+ V+IGK+A +V  + A +Y+ GY +  D    D++     K  Q   GK+++  
Sbjct: 120 DWEGEMAVIIGKRARRVKQADAAEYIAGYAVMNDYTTRDFQYAAPAKTPQWHQGKSLEKS 179

Query: 184 CPIGPWIVTSD--EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241
              GPW+ T D  E G      +   + G + Q + TN  +     +I  ++++  L  G
Sbjct: 180 AGFGPWMTTPDSFEFGG----ELATYLEGEKVQSTPTNDLVFSPEKLIEYITHIYPLDAG 235

Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETR 281
           D+I+TGTPGGVG  RNP  ++  G+ +  EI  +G  E +
Sbjct: 236 DVIVTGTPGGVGHARNPQRYIGDGETVKVEIAGLGFIENK 275


>UniRef50_A6CED1 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Planctomyces maris DSM 8797|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Planctomyces maris DSM 8797
          Length = 310

 Score =  136 bits (329), Expect = 6e-31
 Identities = 83/232 (35%), Positives = 120/232 (51%), Gaps = 15/232 (6%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPE----LPFIFNKFPSTVVG-PNDTIKLK 118
           + L  PV    K+L +  NY  H EE      E     P++F K PST +  P   +K+ 
Sbjct: 80  VQLLVPVPEPSKLLLLAGNYSKHIEEGGGKAEERQKTFPYVFMKPPSTTLTHPGQPVKIP 139

Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNK--------K 170
                 +  E+EL +VIGK    V  + A DYV GYT+  DI    +  N          
Sbjct: 140 EVSPDYIDWELELGIVIGKSCKGVSEAEALDYVAGYTVINDISDRKFRPNPGRTLREKDT 199

Query: 171 ISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIA 230
                 GK  DTFCP+GP +  +D+I +PQ L +K S+NG  +Q ++T + I  +  I+ 
Sbjct: 200 FFDWQHGKWHDTFCPMGPCVTPADDIPDPQTLKMKLSVNGNVEQDASTAEMIFPVAAIVE 259

Query: 231 RLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
            +S+ + L PGD+I TGTP GVG  +N  +FL+ GDV+ +EI+ IG     V
Sbjct: 260 FISSFVQLEPGDVISTGTPSGVGASKN--KFLKNGDVMKAEIDQIGVLTNPV 309


>UniRef50_UPI000038DFF7 Cluster: hypothetical protein Faci_03001459;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03001459 - Ferroplasma acidarmanus fer1
          Length = 274

 Score =  135 bits (327), Expect = 1e-30
 Identities = 80/211 (37%), Positives = 116/211 (54%), Gaps = 8/211 (3%)

Query: 76  VLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           +LC+GLNYK H  E      PE P +F+K  +   G +  ++    +      E EL V+
Sbjct: 69  LLCIGLNYKSHVSEHAGGKIPETPVVFSKANNAFTGNHSIVQTGNGMHMDY--EGELCVM 126

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IGK A  V  ++A +YVLGY I  D+ +   +   K +Q  LGK+ D F P GP+I +  
Sbjct: 127 IGKTARNVGEANALNYVLGYFIGNDVSSRLMQY--KTTQFFLGKSFDNFYPNGPYI-SIG 183

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV-- 252
           EI +PQNL ++  +NG  +Q SNT   I  +  +I+ +S  MTL PGD I TGTP GV  
Sbjct: 184 EINDPQNLTIQTRVNGELRQDSNTGLMIFPVNKLISYISQFMTLRPGDCISTGTPAGVIM 243

Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           G+  +  ++L  GD +  +I  +G  ET  E
Sbjct: 244 GMPESNQKWLGKGDKVEVQITGLGKLETTFE 274


>UniRef50_Q11D77 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Mesorhizobium sp. (strain BNC1)
          Length = 293

 Score =  135 bits (327), Expect = 1e-30
 Identities = 88/280 (31%), Positives = 139/280 (49%), Gaps = 28/280 (10%)

Query: 12  DGIRAGFLDGDNVVDINKE---DPKL--PSTLIELLKTNXXXXXXXXXXXXXXX---LSG 63
           DG R G + GD +VD+      DP    P  +++++                     L+ 
Sbjct: 7   DGGRIGVVSGDRIVDVTPAAGVDPASWPPVGMVQVIANFERLRATFQHQLDAGGGKPLAS 66

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFI-------FNKFPSTVVGPNDTIK 116
           + L+ P+   +KV+    NY  H +E K     +          F K  S++ GP D I 
Sbjct: 67  VRLECPIAWPNKVVAFPANYHAHIDEMKAGSGLISNFAAAGQGFFLKANSSLSGPADPIV 126

Query: 117 LKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176
           L     + V  E EL V+IGK+   +   +A  +V GY+   D      E+       ++
Sbjct: 127 LPNLDGREVHHESELAVIIGKRGRNIPRENALQHVFGYSCLIDAVVRGKEER------VM 180

Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236
            K+ DTFCP+GPW+VT++E+ +P N++++ ++NG  +QK+NT   I  +P++IA  S+VM
Sbjct: 181 RKSYDTFCPLGPWLVTAEEVPDPANIDIELTVNGEVRQKANTRALIVDVPEMIAMASSVM 240

Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
           TL PGDII +GTP GVG        + PGD +   I  +G
Sbjct: 241 TLEPGDIIASGTPSGVGP-------MLPGDAVCITIAGVG 273


>UniRef50_Q11E65 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Mesorhizobium sp. BNC1|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Mesorhizobium sp. (strain BNC1)
          Length = 307

 Score =  135 bits (326), Expect = 1e-30
 Identities = 99/298 (33%), Positives = 134/298 (44%), Gaps = 33/298 (11%)

Query: 7   SYKNSDGIRAGFLDGDNVVDINK-----EDPKLPSTLIELLKTNXXXXXXXXXXXXXXXL 61
           SY    GIR   +  D  VD            +P  L +                    L
Sbjct: 8   SYSGPRGIRTAAVKADRYVDAADVTGVAAHASMPGLLADWAAAERPLQAAFAAGQAMVGL 67

Query: 62  SGITLKAPVHGNDKVLCVGLNYKDHCEE----------------QKLTPPELPFIFNKFP 105
             +    P+ G   + C+G NY DH  E                Q+      P+ F K  
Sbjct: 68  PKLVAPLPLPG--AIYCIGANYADHIAEMQGGGTNGASVAAERKQQKEDGLKPWFFIKSS 125

Query: 106 STVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW 165
            +V GP   + L    SK V  E EL VVIG+K+  +   +A   V GYTIA D+ A D 
Sbjct: 126 HSVCGPETKVALPA-TSKKVDWEAELAVVIGRKSRDLTIENALTAVWGYTIANDLSARDL 184

Query: 166 EKNKKISQ-------LLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNT 218
            +   + Q           K+ D  CP+GPWIV++ +I +  +L++  SING   QKSNT
Sbjct: 185 SRRPPLPQGSPFFFDWTSHKSFDDSCPMGPWIVSASQIVDANDLDIGLSINGQPMQKSNT 244

Query: 219 NQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
           +Q I  + + +A LS  +TL PGDIILTGTP GVG  RN    L+P D ++  IE IG
Sbjct: 245 SQMIFTVAEQVAHLSQRITLWPGDIILTGTPAGVGAGRNLS--LKPSDEVSVYIEGIG 300


>UniRef50_Q9HJ20 Cluster: 2-hydroxyhepta-2, 4-diene-1, 7-dioate
           isomerase related protein; n=3; Archaea|Rep:
           2-hydroxyhepta-2, 4-diene-1, 7-dioate isomerase related
           protein - Thermoplasma acidophilum
          Length = 250

 Score =  134 bits (324), Expect = 2e-30
 Identities = 70/219 (31%), Positives = 114/219 (52%), Gaps = 7/219 (3%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128
           P     K+    +N++ H +E     P  P+ F KF + +VG N T     ++ K +  E
Sbjct: 32  PAVNPGKIFLPAVNFRSHSQESDTKFPPKPYFFTKFSNALVGHNGTAHRPREIEK-LDYE 90

Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW---EKNKKISQLLLGKAMDTFCP 185
            E+ +VIGK+  ++    A +Y+ G+TI  D+ A D+   E +      + GKA D   P
Sbjct: 91  GEIGIVIGKRGKRIGVEEAQNYIFGFTIVDDVSARDYQFPEMHPYGYNWVQGKAFDEALP 150

Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
           +GP+IVT DEI  P  L ++  +NG  +Q   T   +  +  +I+ +S  +TL PGD+I 
Sbjct: 151 VGPYIVTRDEIRFP--LKIETRVNGELRQSGTTEDMVFSVEQLISTVSQTITLEPGDLIT 208

Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           TGTP GV  +    ++L  GD ++  +  IG    R+E+
Sbjct: 209 TGTPAGVAAF-TEAKYLSDGDTVSISVSGIGELVHRIED 246


>UniRef50_Q6AFQ8 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=2; Microbacteriaceae|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Leifsonia xyli subsp. xyli
          Length = 291

 Score =  133 bits (322), Expect = 4e-30
 Identities = 74/206 (35%), Positives = 111/206 (53%), Gaps = 2/206 (0%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           +V+ +G NY  H  E KL   +   +F+ +P+++ G   T     D++  V  E EL V+
Sbjct: 83  QVIAIGANYAAHASELKLRSEKAATVFSLWPNSLAGHGGTTSWPGDLATQVDYEAELGVI 142

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IGK A  V +  A DYV GYT+  DI A D + ++  +Q    K+ D F P GP  VT+D
Sbjct: 143 IGKPARDVLAQDALDYVWGYTVVNDITARDLQFSE--AQWSRCKSFDGFTPNGPVAVTAD 200

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           E+ +PQ+L +  +++G   Q ++T   +  + +II  LS   T+  G +I TG+PGG G 
Sbjct: 201 EVPDPQDLWLTTNVDGAILQDASTADMVRSVAEIIEFLSRSATIPAGTLISTGSPGGAGY 260

Query: 255 YRNPPEFLQPGDVITSEIENIGTFET 280
            R PP FL     +T  I  IG   T
Sbjct: 261 SRTPPVFLHDRSTVTVSIGGIGYLTT 286


>UniRef50_A0HII6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Comamonas testosteroni KF-1
          Length = 286

 Score =  133 bits (322), Expect = 4e-30
 Identities = 74/228 (32%), Positives = 119/228 (52%), Gaps = 10/228 (4%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDT 114
           L+ +T    +   +K++C   NY DH +E      Q+    E P     + S        
Sbjct: 59  LADVTFLPVIPRPEKIVCAVRNYMDHHQEVLAAGMQRELSEEPPIFLRVWRSQTAHQGPI 118

Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174
           ++    VS ++  E EL V+IG+    +  + A++++ GY+   D    +W+ + K  Q+
Sbjct: 119 VR--PHVSDSLDWEGELAVIIGQGGRDIAEADAWEHIAGYSCYNDASVREWQFHAK--QI 174

Query: 175 LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSN 234
             GK  ++    GPW+VT+DEI   + L ++  +NG   Q S+T   I  IP +IA  S 
Sbjct: 175 ASGKNFESTGAFGPWMVTADEISPGRELKLETRLNGAVVQSSHTGHMIFSIPRLIAYAST 234

Query: 235 VMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           + TL+PGD+I+TGTP GVG  + P +F++ GDV+  EIE IG     V
Sbjct: 235 IFTLVPGDVIITGTPAGVGWSKKPQQFMKAGDVVEVEIEAIGLLRNPV 282


>UniRef50_Q5KZR6 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=3; Bacillaceae|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Geobacillus kaustophilus
          Length = 262

 Score =  132 bits (320), Expect = 7e-30
 Identities = 82/214 (38%), Positives = 122/214 (57%), Gaps = 14/214 (6%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           ++L AP+     V+ +G NY    E+  +  P++P  F K  S+VVGP   + +   V +
Sbjct: 45  VSLVAPLAPRH-VIGIGANYVASSEQLPVELPDIPVFFFKPSSSVVGPEAEVVIPSGVGE 103

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183
            V  E EL VVIGK+A +V     + Y+ GYT+A D+ A  +          +GK+ DTF
Sbjct: 104 -VKFESELAVVIGKEAKQVSEEDVWSYIFGYTVANDVTAPQFFHPD--GHWTIGKSFDTF 160

Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243
            P+GP I T  E+ +P+ ++VK  +NG +KQ S+T   I  I  +I+ LS+VMTL PGD+
Sbjct: 161 TPLGPVIET--EL-DPRAVSVKARVNGEEKQNSSTKLMIISISKMISYLSHVMTLQPGDV 217

Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGT 277
           ILTG+P G        E + PG VI  +++ IGT
Sbjct: 218 ILTGSPVGA-------ELVGPGTVIECDVDGIGT 244


>UniRef50_A0QV79 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 285

 Score =  132 bits (320), Expect = 7e-30
 Identities = 74/223 (33%), Positives = 120/223 (53%), Gaps = 8/223 (3%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP---PELPFIFNKFPSTVVGPNDTIKLKMD 120
           +TL  PV    KV+C+GLNY  H  E        PE P +F ++PST+      I +  D
Sbjct: 57  VTLVPPVLPGAKVICIGLNYLKHVAEGSYGAEPLPEFPTLFARWPSTLTVDGAQIPVPTD 116

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
             + +  E E+   +G++ S   +  A D V+GY+   D+ A      K  SQ +LGK  
Sbjct: 117 -EEGLDWEGEVVAWVGRELSCATADEALDAVVGYSTFNDVTAR--RAQKITSQWILGKNA 173

Query: 181 DTFCPIGPWIVTSDEIGNPQN-LNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
           D   P+GP +V + ++G+ ++ L V+  +NG   Q ++T++ ++ + + +A +S  +TL 
Sbjct: 174 DRSGPLGP-LVPAHDVGDLRDGLRVRTRVNGTTVQDASTDEMVYTVGETLAHISRTLTLR 232

Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           PGD++ TGTP GVG  R P   L PGD +  E+E +G     +
Sbjct: 233 PGDLLATGTPSGVGYARTPAWLLHPGDHVEVEVEKLGVLRNTI 275


>UniRef50_A0QU69 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 291

 Score =  132 bits (319), Expect = 1e-29
 Identities = 81/228 (35%), Positives = 127/228 (55%), Gaps = 9/228 (3%)

Query: 62  SGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPEL---PFI-FNKFPSTVVGPNDTIKL 117
           +G  L AP+     +   G N+K+H +E K         P+I F +    +VGP D I+ 
Sbjct: 56  AGGRLLAPIKPTKLIHTAG-NFKEHEDESKRVGWSHNVGPWIVFMQNVDAIVGPEDGIRY 114

Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL-L 176
              ++K +  E+EL+VVI +   +     A +YV GY I  D+ A D ++++  S +   
Sbjct: 115 PDHLTKELDYELELSVVINQDVGEFAPEDAMNYVAGYVIFNDVTARDIQRDEMKSGVFGF 174

Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236
            K +D+FCPIGPWIVT+DEI NP +L ++  +NG  +Q+S++++    IP+I+AR S  +
Sbjct: 175 CKGIDSFCPIGPWIVTADEIPNPHDLKMELRVNGEPRQESHSSRMWTTIPEILARYS-PL 233

Query: 237 TLLPGDIILTGTPGGVGVYRNPPE--FLQPGDVITSEIENIGTFETRV 282
               GDI+ TGT  GV  +R   E  +L+ GD +  E+E IG     V
Sbjct: 234 GYSAGDIVTTGTVSGVAGFRVDAEDYYLRVGDSVECEVEKIGVLRNTV 281


>UniRef50_A2BJD1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Hyperthermus butylicus DSM 5456|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Hyperthermus butylicus (strain DSM
           5456 / JCM 9403)
          Length = 338

 Score =  132 bits (318), Expect = 1e-29
 Identities = 73/222 (32%), Positives = 117/222 (52%), Gaps = 2/222 (0%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           LS + L APV   +K++C+G+NY+ H  E  +  P  P +F K  +++VGP D + +   
Sbjct: 107 LSAVRLLAPVDKPEKIICIGVNYRAHARESGVELPGTPNLFVKTGNSIVGPGDPVVVH-S 165

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           V   +  E+EL  VIG  A  +  S A D V G+ +  D+ +   ++   ISQ    K+ 
Sbjct: 166 VGLKLDGEVELAAVIGIPARSIPPSEAPDVVWGFMVLNDVTSRLEQRELGISQWWRAKSH 225

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           DT+ P GP IV    + +  +  ++  ++G+  ++ NT   +H + DI++  S    L+P
Sbjct: 226 DTYAPTGPIIVPRHMV-SIGDTELELVVDGIVARRGNTGDMVHSVWDIVSVASTSALLVP 284

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GDII TGTP G      P +  +PG V+ +    IG  E RV
Sbjct: 285 GDIICTGTPAGTMPDGKPAKTPEPGSVMRACARGIGCIENRV 326


>UniRef50_Q9X4X5 Cluster: DitD; n=3; Proteobacteria|Rep: DitD -
           Pseudomonas abietaniphila
          Length = 293

 Score =  131 bits (317), Expect = 2e-29
 Identities = 81/217 (37%), Positives = 115/217 (52%), Gaps = 6/217 (2%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128
           P+    +V  VGLNY  H +    T PE P  + K  S +VG +D I+    ++  +  E
Sbjct: 63  PLEPGARVFGVGLNYLSHLQHLGSTAPEHPLGYIKPESALVGASDDIQYPA-LTAQLDYE 121

Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188
           +EL  VI +     D   A   +LGYT   DI A D  K      LL  KAMD   P+GP
Sbjct: 122 VELVAVIARALG--DEPCASACLLGYTCGNDISARDAGKRIGRLDLLTQKAMDRTTPVGP 179

Query: 189 WIVTSDEIGNPQ-NLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247
           W+VT DEIG  Q +L+++ S+N   +Q  NT Q +  I +++  +   +TL PGD++ TG
Sbjct: 180 WVVTLDEIGVGQPHLDIELSVNDECRQFDNTRQMLFPIDELLNYVDARITLQPGDLVFTG 239

Query: 248 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           +  GVG+      FLQPGD +   IE IG+   RV +
Sbjct: 240 STHGVGL--EDGRFLQPGDRVEVRIEGIGSMSNRVSQ 274


>UniRef50_A1SM04 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Nocardioides sp. JS614|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 269

 Score =  131 bits (317), Expect = 2e-29
 Identities = 84/224 (37%), Positives = 113/224 (50%), Gaps = 11/224 (4%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L  + L APV    KV+ +G NY  H  E     P  P +F K  ++V+GP D I     
Sbjct: 54  LEDVRLLAPVLPRSKVVGIGRNYAAHAAELGNDLPTEPLMFLKPNTSVIGPGDPIFYPPQ 113

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
               +  E EL VVIG+    V    A D + GYTI  D+ A D +++    Q    K  
Sbjct: 114 TQN-LHYEGELAVVIGRICRDVPPEQATDVIHGYTIGNDVTARDLQRSDV--QFTRAKGF 170

Query: 181 DTFCPIGPWIVTS-DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
           D+FCP+GPWI T  D     +  +V+  +NG   Q  +T   I  IP +IA +S+VMTLL
Sbjct: 171 DSFCPLGPWIETDLDPHDFAEGRSVQTHLNGDLVQDGSTKDLIFDIPTLIAYVSSVMTLL 230

Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           PGD+ILTGTP GVG        +  GD +   I  +GT    V+
Sbjct: 231 PGDVILTGTPEGVGP-------MDVGDEVEVSIAGLGTLTNPVK 267


>UniRef50_Q9F135 Cluster: Putative uncharacterized protein xlnF;
           n=1; Pseudomonas alcaligenes|Rep: Putative
           uncharacterized protein xlnF - Pseudomonas alcaligenes
          Length = 287

 Score =  131 bits (316), Expect = 2e-29
 Identities = 82/233 (35%), Positives = 119/233 (51%), Gaps = 23/233 (9%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP-----PELPFI-----FNKFPSTVVG 110
           L  +TL +PV    K++   +NY DH +E           E+  I     F K  S+ VG
Sbjct: 68  LDAVTLISPVGNPGKIIAAPVNYADHLDESNQDKGINFGTEISLIDKYALFLKAGSSSVG 127

Query: 111 PNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK 170
           P++ I L     +    E+EL +VIGK+  +V    A   V GY I  DI     E    
Sbjct: 128 PDEGISLPAVEGRRFDHEVELALVIGKETRRVTVDEALSSVAGYFIGLDITMRGTEDRS- 186

Query: 171 ISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIA 230
                  K+ D+F  +GPW+VTSD  G+P+ +    S+NG Q+Q +NTN  +  +  II+
Sbjct: 187 -----YRKSFDSFTVMGPWLVTSDAFGSPEGVAFSLSVNGEQRQNANTNDLVWSVAKIIS 241

Query: 231 RLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
             S+  TL PGD+ILTGTP GVG        ++ GD I++ I+ IG+ E  V+
Sbjct: 242 VASHAYTLYPGDVILTGTPAGVGP-------IKAGDKISASIDRIGSMEVPVK 287


>UniRef50_A2QL54 Cluster: Contig An05c0060, complete genome; n=6;
           Pezizomycotina|Rep: Contig An05c0060, complete genome -
           Aspergillus niger
          Length = 290

 Score =  131 bits (316), Expect = 2e-29
 Identities = 79/214 (36%), Positives = 112/214 (52%), Gaps = 9/214 (4%)

Query: 76  VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND-TIKL-KMDVSKAVVCEIELTV 133
           + C+GLNY DH +E  L  PE+P +F K  S ++GP   +I + K         E EL V
Sbjct: 76  IRCLGLNYIDHAKEANLALPEVPILFTKPRSALIGPYPASISVPKCAQDGTSDYESELCV 135

Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG-----P 188
           VIG+    +   +A DYVLGYT + D+ A   +     +Q    K +D  CPIG     P
Sbjct: 136 VIGRTGRDIPEENALDYVLGYTASNDVSARTLQM--ATAQWSFSKGLDESCPIGIDRTGP 193

Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248
            +V+   I +PQ L ++   NGV  Q  +T   I  I   I+ LS   TL  G I LTGT
Sbjct: 194 VLVSPSVIKDPQTLRIQGIHNGVVVQDGHTKDMIFSIKRQISYLSQGTTLEAGTIFLTGT 253

Query: 249 PGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           P G+G +++P + L+ GD  +  I+ IGT   +V
Sbjct: 254 PAGIGYFKSPRDVLKDGDEFSVYIDKIGTLTNKV 287


>UniRef50_Q3S4C0 Cluster: Putative hydratase; n=2;
           Proteobacteria|Rep: Putative hydratase - Polaromonas
           naphthalenivorans (strain CJ2)
          Length = 289

 Score =  130 bits (315), Expect = 3e-29
 Identities = 95/290 (32%), Positives = 137/290 (47%), Gaps = 33/290 (11%)

Query: 12  DGIRAGFLDGDNVVDINKEDPKLPS---------TLIELLKTNXXXXXXXXXXXXXXXLS 62
           D  R G +DG+ V D+      LP+          LI LL                  L+
Sbjct: 7   DNDRLGLVDGETVRDVTAALDVLPNHRYPLPIFDPLIALLPEVLEAIRRIAPSSPTLPLA 66

Query: 63  GITLKAPVHGNDKVLCVGLNYKDHCEEQK----------LTPPELPFIFNKFPSTVVGPN 112
           G  L APV    KV+   +NYK H +E +          +   E   +F K  S+VVGP+
Sbjct: 67  GRRLLAPVANPGKVIAAPVNYKKHLQEAREQVEIHHNNQVAEIEKIGLFLKATSSVVGPS 126

Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS 172
             ++++    +    E EL  VIGK    +    AFD++  YTI  D+     ++     
Sbjct: 127 HGVEIQHP-DRRNDHEAELVAVIGKTGRNIPRERAFDHISAYTIGLDMTVRGPQERS--- 182

Query: 173 QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 232
              L K++DT+  +GPW+VT+DEI +PQ L+   ++NG ++QK+NT   +  IP +I   
Sbjct: 183 ---LRKSIDTYSVVGPWLVTADEIDDPQALDFWLTVNGERRQKANTRDLVLDIPALIEMA 239

Query: 233 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           S+  TL PGD++ TGTP GVG   N       GD IT EI  IG     V
Sbjct: 240 SSYYTLQPGDLLFTGTPEGVGPVVN-------GDEITVEIAGIGRMNVAV 282


>UniRef50_Q979A6 Cluster: 2-hydroxyhepta-2,4-diend-1,7-dioate
           isomerase; n=1; Thermoplasma volcanium|Rep:
           2-hydroxyhepta-2,4-diend-1,7-dioate isomerase -
           Thermoplasma volcanium
          Length = 268

 Score =  130 bits (315), Expect = 3e-29
 Identities = 72/217 (33%), Positives = 113/217 (52%), Gaps = 7/217 (3%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128
           P     K+    +N++ H  E     P  P+ F KF + +V  N  ++    + K +  E
Sbjct: 55  PAVNPQKIFLPAVNFRSHSAESDTRFPPKPYFFTKFSNALVANNSELRTPGTIKK-LDYE 113

Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW---EKNKKISQLLLGKAMDTFCP 185
            E   VIGKK   + +  A+D + G+TIA D+ A D+   E +      + GKA D   P
Sbjct: 114 GETGAVIGKKCYNIPAEDAYDCIFGFTIANDLSARDFQFPEMHPYGYNWVQGKAFDGALP 173

Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
           +GP+I T DEI  P  L ++  +NG  +QK  T+  +    D+I+ LS  +TL PGDII 
Sbjct: 174 VGPYITTKDEIQFP--LEIETKVNGETRQKGTTDDMVFSFQDLISTLSQNITLEPGDIIT 231

Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           +GTP GV  + +   +L+ GDVI   + ++GT   ++
Sbjct: 232 SGTPAGVAAF-SEKLYLKSGDVIEISVSSLGTLMNKI 267


>UniRef50_Q9LBE3 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase-related protein; n=4; Deinococci|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate
           decarboxylase-related protein - Deinococcus radiodurans
          Length = 250

 Score =  130 bits (314), Expect = 4e-29
 Identities = 83/223 (37%), Positives = 117/223 (52%), Gaps = 17/223 (7%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPF---IFNKFPSTVVGPNDTIKL 117
           LS   L AP   + K++CVG NY DH  E      +LP    IF K P+ +  P  T++ 
Sbjct: 39  LSEARLLAPAEPS-KIVCVGRNYLDHIRELGNDTGDLPAEPGIFLKGPNALAEPGGTVEY 97

Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177
               S+    E EL +VIG++A  + +  A   VLGYT   D+ A D +K     Q    
Sbjct: 98  P-SWSENFHFEGELALVIGQRARNLKADEALGAVLGYTCGLDLTARDRQKTDL--QWFRA 154

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           KA D FCP+GPW+VT  +   P ++ V+  +NG  +Q   T+  I  +  I+  L+  +T
Sbjct: 155 KAADRFCPLGPWLVTQFD---PSDVRVQTRVNGEPRQDGRTSHMIFDVVQILTYLTRFVT 211

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFET 280
           L PGD++LTGTP GVG        LQ GD +  E++ IG  ET
Sbjct: 212 LEPGDVVLTGTPEGVGP-------LQRGDRVEVEVDGIGVLET 247


>UniRef50_Q74FM1 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=8; Desulfuromonadales|Rep:
           Fumarylacetoacetate hydrolase family protein - Geobacter
           sulfurreducens
          Length = 218

 Score =  130 bits (314), Expect = 4e-29
 Identities = 71/211 (33%), Positives = 113/211 (53%), Gaps = 11/211 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K+LC+G NY +H +E     P+ P +F K  + V+G  +TI +    S+    E EL ++
Sbjct: 17  KILCIGRNYAEHIKELGNETPDAPVVFMKPATAVIGDGETIIIP-SYSRECHHEAELALL 75

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 192
           IGK    +    A ++V GY +A D+   D   E  KK     + K  DT CP+  + V 
Sbjct: 76  IGKGGKDIPPERALEHVAGYGVAIDLTLRDVQAELKKKGLPWEIAKGFDTSCPLSSF-VP 134

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252
           +D + +P +L++   +NG  +Q  +++  IH+IP I++ +S V TL PGD+ILTGTP GV
Sbjct: 135 ADRVADPHDLHITLRVNGEMRQDGSSSLMIHRIPQILSYMSGVFTLEPGDVILTGTPAGV 194

Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           G        L  GD + +E+  +      V+
Sbjct: 195 GP-------LAAGDAVEAEVVGVAAIRVTVK 218


>UniRef50_O30145 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Archaeoglobus fulgidus|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Archaeoglobus fulgidus
          Length = 324

 Score =  130 bits (314), Expect = 4e-29
 Identities = 83/233 (35%), Positives = 126/233 (54%), Gaps = 15/233 (6%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHC----EEQKLTPPE----LPFIFNKFPSTVVGPN 112
           LS + LKAP+    K++     +++H     E+  ++ P+    +P  +   P +V+GP 
Sbjct: 93  LSEVKLKAPL--KPKLMVDFSTFEEHVRMGFEKLGMSIPQEWYQVPVGYKMNPYSVIGPE 150

Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNK-KI 171
           + + +    ++ +  E+E  +V+GK+   V    A DYVLGYTI  DI A D E  + K 
Sbjct: 151 EPV-IWPSFTQILDYELEFGIVVGKRGKNVSKEDAMDYVLGYTIVNDISARDMEFIELKA 209

Query: 172 SQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDII 229
             L  L  K  D   P+GP IVT DEI +P NL +   +NG    +++T     KIPD+I
Sbjct: 210 MPLGPLKSKDFDNATPMGPCIVTKDEIKDPHNLKMVARVNGEVWSEASTKDMHWKIPDLI 269

Query: 230 ARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           A LS   T+ PG ++L+GTPGG G   +  + L+PGDV+  EIE IG     +
Sbjct: 270 AHLSKDQTIHPGTVMLSGTPGG-GCGMHVGKLLKPGDVVELEIEGIGVLRNPI 321


>UniRef50_Q6BTI3 Cluster: Similar to CA3735|IPF5534 Candida albicans
           IPF5534 5-oxo-1; n=1; Debaryomyces hansenii|Rep: Similar
           to CA3735|IPF5534 Candida albicans IPF5534 5-oxo-1 -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 289

 Score =  129 bits (312), Expect = 7e-29
 Identities = 78/224 (34%), Positives = 114/224 (50%), Gaps = 9/224 (4%)

Query: 66  LKAPVHGNDK--VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           L  P+ G D   V C+G+NYK+H     + PP  P +F K  ++V   N+ I + +    
Sbjct: 67  LLGPLTGEDVPVVKCIGMNYKEHLMGI-IEPPPYPQLFYKPRTSVADQNEDIPIPLFAQN 125

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW----EKNKKISQLLLGKA 179
               E EL VVIGK    ++   A  YV GY    D+ A DW    E   K+ QL   K+
Sbjct: 126 TCDYEGELCVVIGKTGKNINEEDALSYVAGYVSGNDLSARDWQYFPEYAGKVPQLGFSKS 185

Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
            D + P+GP IV+S  I +P  L ++  ING  +Q   T+  +  I  IIA +S   TL 
Sbjct: 186 FDRYAPLGPAIVSSKIIKDPHALQLQTRINGDLRQNCGTDDLLFGISRIIAFISQETTLE 245

Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
            G +I+TGTP G G      ++L+ GD++   I+ IGT   + +
Sbjct: 246 QGTVIMTGTPNGCGGIDG--KYLKDGDLVEVTIDQIGTLSHKTK 287


>UniRef50_A7D5S8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Halorubrum lacusprofundi ATCC
           49239|Rep: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase - Halorubrum lacusprofundi ATCC 49239
          Length = 304

 Score =  129 bits (312), Expect = 7e-29
 Identities = 71/205 (34%), Positives = 109/205 (53%), Gaps = 12/205 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++C+G NY DH  E     P+ P +F K P+ +    D I +     + +  E E+ VV
Sbjct: 106 KIVCIGRNYADHAAELDNDVPDRPLLFLKPPNALASHGDEITVPAGKDR-IDWEAEIAVV 164

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IG++   VD+  A D V G+T   D+   D +  ++    + GKA D   P+GP + T D
Sbjct: 165 IGEQCKDVDADDAMDVVAGFTCMNDVSNRDDQDREQ--NWVRGKAFDGAAPLGPVMATPD 222

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           E+  P + +V+  +NG  KQ S+ +  +  +P +I  ++  +TL PGD+I TGTP GVG 
Sbjct: 223 EV--PADASVELRVNGETKQSSDRSYLMFDVPTLIEEITTYLTLEPGDVISTGTPEGVGA 280

Query: 255 YRNPPEFLQPGDVITSEIENIGTFE 279
                  L  GD +  EIE +GT E
Sbjct: 281 -------LSDGDTVEVEIEGVGTLE 298


>UniRef50_A3EQW7 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Leptospirillum sp. Group II UBA|Rep:
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Leptospirillum sp. Group II UBA
          Length = 267

 Score =  128 bits (310), Expect = 1e-28
 Identities = 80/217 (36%), Positives = 118/217 (54%), Gaps = 14/217 (6%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L  + L  PV    K++ VGLNY+ H  E     PE P +F K  S ++ PN  I+L   
Sbjct: 47  LLDVRLHPPVTPG-KIIAVGLNYRAHGNEMGKPLPEEPLLFMKATSALLPPNGEIRLPR- 104

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
           +S+ V  E E+ +V+GKKAS +       +V G T A D+ A D +K  K  Q    K+ 
Sbjct: 105 MSRRVDFEGEIALVMGKKASGISPEEVPLFVYGITCANDVTARDLQK--KDVQYTRAKSF 162

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           DTFCP+GP I+T      P +  ++  +NGV +Q++  +  I     +++ +S VMTL P
Sbjct: 163 DTFCPLGPVILTG---ALPDDRRLRTEVNGVVRQEARASDMIFDPLTLVSFISQVMTLEP 219

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGT 277
           GD+ILTGTP GVG        L P D ++  +E +G+
Sbjct: 220 GDVILTGTPSGVGP-------LSPMDRVSVSLEGVGS 249


>UniRef50_Q2USU7 Cluster: RIB40 genomic DNA, SC005; n=6;
           Pezizomycotina|Rep: RIB40 genomic DNA, SC005 -
           Aspergillus oryzae
          Length = 299

 Score =  128 bits (308), Expect = 2e-28
 Identities = 75/213 (35%), Positives = 109/213 (51%), Gaps = 9/213 (4%)

Query: 78  CVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND--TIKLKMDVSKAVVCEIELTVVI 135
           CVGLNY  H +E    PP  PFIF K P+T V  +    +  ++  +     E EL ++I
Sbjct: 85  CVGLNYAKHIKEAGRKPPPFPFIFFK-PNTCVHDHGKPVVIPRIAQNDQADYEGELCLII 143

Query: 136 GKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK----ISQLLLGKAMDTFCPIGPWIV 191
           GK A  V   HA +YV  YT   DI +   +++      + Q    K  DTF P+GP +V
Sbjct: 144 GKDAKDVSPEHALEYVAAYTAGNDISSRKLQRDPAYAGVVPQWGFSKGFDTFAPLGPVLV 203

Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251
            + EI +P  L++K  ++G  +Q       +     +I+ LS   TL  G +I+TGTPGG
Sbjct: 204 AASEIPDPSQLHLKTIVDGEVRQDETVGDLLFDCKYLISYLSQGTTLQKGSVIMTGTPGG 263

Query: 252 VGVYR--NPPEFLQPGDVITSEIENIGTFETRV 282
           +GV     PP++L PG  +  +I  IGT    V
Sbjct: 264 LGVGAGFKPPKWLVPGTQMDVQISQIGTLRNNV 296


>UniRef50_Q2NHN7 Cluster: Predicted 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=1; Methanosphaera stadtmanae DSM 3091|Rep: Predicted
           2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic
           acid hydratase - Methanosphaera stadtmanae (strain DSM
           3091)
          Length = 256

 Score =  128 bits (308), Expect = 2e-28
 Identities = 78/209 (37%), Positives = 112/209 (53%), Gaps = 16/209 (7%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCE 128
           P     K++CVGLNYKDH +E  +  P+ P +F K  ++V+  N  I +    +  +  E
Sbjct: 58  PPTNPSKIVCVGLNYKDHAKELNMELPDEPLLFMKPSTSVISTNSAI-IYPSTTNMLDFE 116

Query: 129 IELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGP 188
            EL +VI +K S  D+       + YTI  D+ A D +   K  Q    K+ DTFCP GP
Sbjct: 117 GELGIVILEKVSPCDNGTCN---VAYTIVNDVTARDLQS--KDGQWTRSKSYDTFCPCGP 171

Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248
            +VT  +     NLN+K  +N   KQ+SNT   I    +++  +SN+MTL PGDII +GT
Sbjct: 172 VVVTGID---SSNLNIKTMVNNDIKQESNTKNMIFSPLELVKYISNIMTLNPGDIIASGT 228

Query: 249 PGGVGVYRNPPEFLQPGDVITSEIENIGT 277
           P GVG        L  GD +  EI+ +G+
Sbjct: 229 PPGVG-------HLDVGDTVVVEIDEMGS 250


>UniRef50_A6W055 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Marinomonas sp. MWYL1|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Marinomonas sp. MWYL1
          Length = 245

 Score =  127 bits (307), Expect = 3e-28
 Identities = 73/212 (34%), Positives = 112/212 (52%), Gaps = 10/212 (4%)

Query: 73  NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 132
           N+K L   L  K   E+  + PP+ P +  K  +T +G   +IKL  D   AV     L 
Sbjct: 43  NNKALAKSLE-KAFNEKPHVQPPKTPVLHIKTDNTHIGYGKSIKLPSDKG-AVFAGPSLG 100

Query: 133 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVT 192
           +VIGKK ++VD+S+A D V G+T+  ++   +    +   +    K  DTFCPIGPW V 
Sbjct: 101 IVIGKKTTRVDASNALDCVAGFTVVNEVSLAETSFYRPAVK---AKCRDTFCPIGPWSVD 157

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252
              +  P  L++K  IN     ++NT+Q I+ + +I++ +S+ MTL  GDII+ GTP   
Sbjct: 158 KSAVSTPNKLSIKTFINDALVHETNTDQLIYSVEEIVSYISSFMTLEAGDIIIAGTP--- 214

Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
              R     + PGD +  +IE +G     VE+
Sbjct: 215 --ERTADLAINPGDSVMIDIEGVGRLVNPVEQ 244


>UniRef50_Q0SFL0 Cluster: Maleylpyruvate isomerase; n=4;
           Actinomycetales|Rep: Maleylpyruvate isomerase -
           Rhodococcus sp. (strain RHA1)
          Length = 275

 Score =  126 bits (305), Expect = 5e-28
 Identities = 70/211 (33%), Positives = 111/211 (52%), Gaps = 5/211 (2%)

Query: 68  APVHGND-KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV 126
           APV  N  K++CVGLNY +H +E     PE P +F KF   + GP D + +    +  + 
Sbjct: 61  APVVPNPGKIICVGLNYANHIQEMGRDLPEYPTLFAKFKEALTGPYDDVIVPSYAAAQLD 120

Query: 127 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPI 186
            E EL  V+GK+A +V  + A  Y+ GY++  D    D++   +  Q   GK  +     
Sbjct: 121 WEGELAFVVGKQAYQVPEADAEQYIAGYSVMNDYTMRDYQ--YRTLQWDQGKTFEKTSGF 178

Query: 187 GPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILT 246
           GP++ T+D       L  K  + G   Q + T+  +     ++  +S+++TL PGD+++T
Sbjct: 179 GPFLTTTDSYTFGGTLVTK--LEGQVVQSTTTDDLVFTPARLVEYISHIVTLQPGDVVIT 236

Query: 247 GTPGGVGVYRNPPEFLQPGDVITSEIENIGT 277
           GTPGGVG  R P  ++Q G  +   IE +GT
Sbjct: 237 GTPGGVGHARKPGLYIQDGQTVEVTIEGLGT 267


>UniRef50_Q5KN08 Cluster: Mitochondrion protein, putative; n=14;
           Dikarya|Rep: Mitochondrion protein, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 311

 Score =  126 bits (303), Expect = 8e-28
 Identities = 77/214 (35%), Positives = 114/214 (53%), Gaps = 8/214 (3%)

Query: 76  VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVG---PNDTIKLKMDV-SKAVVCEIEL 131
           + C+GLNY +H +E  L  P++P +F K PST +    P+ TI  K  V S +   E E+
Sbjct: 99  IRCIGLNYVNHAKEVNLPMPDIPTLFMK-PSTSLADPFPSPTIIPKAFVASNSADFESEV 157

Query: 132 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 191
             VIGK A  V    A DYVLG+T A D+ + + +  +  SQ    K+ D  CPIGP +V
Sbjct: 158 AFVIGKDAKNVSEEEALDYVLGFTAANDVSSREAQFAQ--SQWCYSKSFDGACPIGPALV 215

Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251
             ++     ++ ++ S+NG   Q S  +  I  +P I++ LS   TL  G II+TGTP G
Sbjct: 216 NKNQANKFSDVKIEGSLNGKTVQSSRLDDLIFSVPKIVSFLSQGTTLPAGTIIITGTPAG 275

Query: 252 VGVYRNPPEFLQPGDVITSEIEN-IGTFETRVEE 284
           VG    P   L+ GD     + + +GT   ++ E
Sbjct: 276 VGWSSTPRITLKDGDEFRVFVSHGVGTLINKIVE 309


>UniRef50_Q5KAM1 Cluster: Mitochondrion protein, putative; n=3;
           Eukaryota|Rep: Mitochondrion protein, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 228

 Score =  126 bits (303), Expect = 8e-28
 Identities = 71/183 (38%), Positives = 104/183 (56%), Gaps = 8/183 (4%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC--EIELT 132
           K++ +G NY DH +E     P+ PF F K  S+ + P++     +++ + V+   E+EL 
Sbjct: 10  KIVAIGRNYADHAKELGNAIPKEPFFFLKPTSSYLVPDNG---PVEIPRGVIVHHEVELG 66

Query: 133 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWI 190
           VVIGK    +  S AFD+V GY++A D+ A + +   K   L     K  DTFCPIGP+I
Sbjct: 67  VVIGKNGRDISPSAAFDHVAGYSLAVDMTARNVQDKAKAKGLPWSAAKGFDTFCPIGPFI 126

Query: 191 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 250
                I +P  + +  S+NG  KQ   T+  I  IP +IA +S +M L  GD++LTGTP 
Sbjct: 127 -PKHFIADPTKVGLHFSVNGTVKQSGLTSDMIFDIPQLIAFVSGIMKLEEGDLVLTGTPS 185

Query: 251 GVG 253
           GVG
Sbjct: 186 GVG 188


>UniRef50_A2U6Z6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Bacillus coagulans 36D1|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Bacillus coagulans 36D1
          Length = 278

 Score =  125 bits (302), Expect = 1e-27
 Identities = 85/228 (37%), Positives = 107/228 (46%), Gaps = 20/228 (8%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELP------FIFNKFPSTVVGPNDT 114
           L+G+TLK PV G  K+    +NY  H EE        P       +F K P ++ GP D 
Sbjct: 63  LNGVTLKCPVPGAGKIWAAPVNYLKHQEEMNHQFNNAPRTIEELSLFLKSPQSLSGPTDP 122

Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174
           I L     +    E EL  ++GKKA  V +  A DY+ GY    DI     E+       
Sbjct: 123 IILPFP-ERRTDHEAELGYIVGKKAKNVKAREAKDYIFGYFALLDISIRGNEERT----- 176

Query: 175 LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSN 234
              K+ DTF PIGPWIVT DEI NP +L +   +N   +Q  +T   I+          +
Sbjct: 177 -WRKSFDTFTPIGPWIVTEDEIKNPNDLAISLWVNDELRQSGSTKYLIYDCYKCFELACD 235

Query: 235 VMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
            MTL PGDII TGTP GVG  R        GD +   IE IG F   V
Sbjct: 236 HMTLHPGDIIATGTPEGVGPIRE-------GDRVKISIEQIGEFTVDV 276


>UniRef50_P34673 Cluster: Uncharacterized protein ZK688.3; n=5;
           Eukaryota|Rep: Uncharacterized protein ZK688.3 -
           Caenorhabditis elegans
          Length = 214

 Score =  125 bits (302), Expect = 1e-27
 Identities = 70/180 (38%), Positives = 101/180 (56%), Gaps = 4/180 (2%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++CVG NYKDH  E     P+ P +F K  ++ +   + I         +  E+EL VV
Sbjct: 13  KIVCVGRNYKDHALELGNAIPKKPMLFVKTVNSFIVEGEPIVAPPGCQN-LHQEVELGVV 71

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVT 192
           I KKAS++  S A DY+ GYT+A D+ A D+  E  K  +   L K+ D  CPIG ++  
Sbjct: 72  ISKKASRISKSDAMDYIGGYTVALDMTARDFQDEAKKAGAPWFLAKSFDGSCPIGGFLPV 131

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252
           SD I NP ++ + C ING  +Q+  T+  I  IP ++   +   TL  GD++LTGTP GV
Sbjct: 132 SD-IPNPHDVELFCKINGKDQQRCRTDVMIFDIPTLLEYTTQFFTLEVGDVVLTGTPAGV 190


>UniRef50_Q7BRJ5 Cluster: DitM; n=5; Proteobacteria|Rep: DitM -
           Pseudomonas abietaniphila
          Length = 289

 Score =  125 bits (301), Expect = 1e-27
 Identities = 78/229 (34%), Positives = 118/229 (51%), Gaps = 11/229 (4%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           LS +TL  P+   ++V+  G NY  H  E  L+ P  P  F K    ++G +D I+    
Sbjct: 57  LSQVTLLPPIEPVNRVVVAGANYAKHLVEFGLSAPSQPVAFLKAYGALIGAHDPIRFP-P 115

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN--KKIS-QLLLG 177
           ++  +  E+EL  VIG  +  VD       VLGYT+  D+ A D +++  K I   L   
Sbjct: 116 LTTELDHEVELVAVIG--SDDVDLDDPLACVLGYTVGNDVSARDLQRSGPKGIGMDLFAA 173

Query: 178 KAMDTFCPIGPWIVTSDEI--GNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNV 235
           K+ D    +GPW+VT DE+  G+P+ L +   +NG  +Q  NT      + ++IA +   
Sbjct: 174 KSQDKTTGLGPWVVTKDELPEGSPK-LRLTLKVNGQMRQDGNTADMTWDVGELIAFVQQR 232

Query: 236 MTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
            +   GD++ TG+P GVG+      FL PGDV+ + IE IGT    V E
Sbjct: 233 SSFACGDVLFTGSPAGVGM--GTGIFLDPGDVVEASIEGIGTLRNVVGE 279


>UniRef50_Q4JXJ3 Cluster: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Corynebacterium jeikeium (strain K411)
          Length = 272

 Score =  124 bits (299), Expect = 3e-27
 Identities = 67/209 (32%), Positives = 108/209 (51%), Gaps = 13/209 (6%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K+ CVGLNY++H  E     P+ P +F K+ S + GP D + +  ++S     E EL V+
Sbjct: 74  KIFCVGLNYREHIAEMGHPIPDHPTLFVKYASALAGPFDEVVVPPELSAQADYEGELAVI 133

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           +G+          F  + GYT+  D    DW+   +  Q L GK +D     GPW+V ++
Sbjct: 134 MGE----------FGQIAGYTVMNDFSQRDWQY--RTQQWLQGKNLDRSSGFGPWMVPTE 181

Query: 195 EIGN-PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
                 +   ++  +NG  +Q+ +    + K  D++  +SN  +L PGD+I+TGTP GVG
Sbjct: 182 HFDPIAEGAVLRTWVNGELRQEHSVADLVFKPQDLVDYISNFASLAPGDVIVTGTPEGVG 241

Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRV 282
               PP++L  GD +   I+ IG    R+
Sbjct: 242 HGMTPPQYLADGDEVRIAIDGIGEICNRI 270


>UniRef50_Q01DJ4 Cluster: Predicted fumarylacetoacetate hydralase;
           n=2; Ostreococcus|Rep: Predicted fumarylacetoacetate
           hydralase - Ostreococcus tauri
          Length = 322

 Score =  124 bits (299), Expect = 3e-27
 Identities = 77/223 (34%), Positives = 116/223 (52%), Gaps = 18/223 (8%)

Query: 76  VLCVGLNYKDHCEE--------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 127
           + CVG NY +H  E         ++  PE P IF+K  +++     +I  +    K V  
Sbjct: 102 IACVGKNYLEHVGEVDSTMPGISRMDVPEAPIIFSKASTSLNAHLGSIATRG--RKDVDY 159

Query: 128 EIELTVVIGKKASKVDSSHAFD-----YVLGYTIAQDIGATDWEKNKKISQLLLGKAMDT 182
           E EL  VIG++   +D   + +     YV+G++IA D+ A + +K  +  Q  LGK+ DT
Sbjct: 160 EGELVAVIGRECRDIDPGMSDEDVVKNYVIGWSIANDVTARELQKTHQ--QWFLGKSGDT 217

Query: 183 FCPIGPWIVTSDEIGNPQNL-NVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241
            CP+GPW+   D         ++  ++N   +Q+S  +Q I  +  +IA +S   TL  G
Sbjct: 218 HCPLGPWVCCDDGRAPALGAASITTAVNSEIRQRSTVDQLIWSVGALIACISRHQTLRVG 277

Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           D +LTGTP GVG   +PP FLQPGD     IE +GT +  V E
Sbjct: 278 DCVLTGTPSGVGAGFDPPRFLQPGDACEVTIEGVGTLKNTVVE 320


>UniRef50_A7EGL0 Cluster: 2-keto-4-pentenoate hydratase; n=6;
           Ascomycota|Rep: 2-keto-4-pentenoate hydratase -
           Sclerotinia sclerotiorum 1980
          Length = 241

 Score =  123 bits (297), Expect = 5e-27
 Identities = 72/227 (31%), Positives = 122/227 (53%), Gaps = 8/227 (3%)

Query: 63  GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122
           G+   +P     KV+C+G NY DH  E   + P+ PF F K PS+++ PN    ++    
Sbjct: 8   GLATVSPFKSASKVVCIGRNYADHITELNNSKPKQPFFFLKPPSSILPPNGGAVIRPK-G 66

Query: 123 KAVVCEIELTVVIGKKASKVDSSH---AFDYVLGYTIAQDIGATDWEKNKKISQLL--LG 177
             +  E+EL +++GK+   ++  +   A+D +  Y ++ D+ A + +   K   L   + 
Sbjct: 67  VDLHYEVELALIMGKQLKNLEPENEKEAYDSIESYAMSIDMTARNAQNEAKKKGLPWDIA 126

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           K  DTF P+   I++  +I +P N  V  ++N   +QK +T   +++IP I++ +S VMT
Sbjct: 127 KGFDTFLPMSN-IISKSQIPDPHNATVWLTVNNEHRQKDSTELMLYRIPRILSDISKVMT 185

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           L  GDI+LTGTP GVG  + P + ++ G  +  +    G  E  VEE
Sbjct: 186 LEKGDIVLTGTPKGVGSVK-PGDVMRVGISVGGKELTEGKIEVAVEE 231


>UniRef50_Q8EMH6 Cluster: 4-hydroxyphenylacetate degradation
           bifunctional isomerase : decarboxylase; n=2;
           Bacillaceae|Rep: 4-hydroxyphenylacetate degradation
           bifunctional isomerase : decarboxylase - Oceanobacillus
           iheyensis
          Length = 263

 Score =  122 bits (294), Expect = 1e-26
 Identities = 79/232 (34%), Positives = 116/232 (50%), Gaps = 21/232 (9%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHC--------EEQKLTPPELPFIFNKFPSTVVGPN 112
           L  ++L  P++G   V    LNYK           E+   TPP+ P ++ K  +T +G  
Sbjct: 35  LDDLSLDVPINGT--VYGTLLNYKGEYAELESSMNEDPYKTPPKAPILYIKPINTHIGYG 92

Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS 172
            TI L   V K  +    L VVIGK A  +   +A DYV GYTI  D+   +    +   
Sbjct: 93  MTIPLPEGVEKVSI-GAALGVVIGKPAKNIRKENALDYVAGYTIVNDVSIPNESYYRPAY 151

Query: 173 QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARL 232
           +    KA D FCPIGPW++  D I NP  L ++  ING  KQ++ T+  I  +  ++  +
Sbjct: 152 K---EKARDGFCPIGPWVLRRDAIENPNELGIRVYINGEIKQENTTSNLIRSVEQLMEEV 208

Query: 233 SNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           ++ MTL  GD++L G P       N P   +  D +  EI+NIGT   +VE+
Sbjct: 209 TDFMTLYEGDVLLVGVP------ENAP-IAKENDRVIIEIDNIGTLVNKVEK 253


>UniRef50_A0IRN0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=4;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Serratia proteamaculans 568
          Length = 287

 Score =  122 bits (293), Expect = 1e-26
 Identities = 79/234 (33%), Positives = 117/234 (50%), Gaps = 24/234 (10%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEE----QKLTPPELPF------IFNKFPSTVVG 110
           L  ++L APV    K++   +NY+DH  E    Q++   ++        +F K  S++ G
Sbjct: 65  LEQVSLNAPVANPGKIVAAPINYRDHIAEANADQQINHGKVYTDISEYGLFLKANSSLCG 124

Query: 111 PNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK 170
           PN+ I L +   +    E+EL V+IG++A  +    A + V GY I  D+     E    
Sbjct: 125 PNEIIPLPIP-GRRTDPEVELAVIIGQRARNLPVDQALEAVFGYAIGIDMTVRGSEFPS- 182

Query: 171 ISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIA 230
                  K+ D F  +GPWIVT DEIG+P  L++   +NG  +Q SNT   I+ +  +IA
Sbjct: 183 -----FRKSADGFSVLGPWIVTPDEIGDPNTLDLSIRVNGQLRQHSNTRHLIYNVQRLIA 237

Query: 231 RLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
             S + TL PGD+I TGTP GV         +Q GD I   IE IG     + +
Sbjct: 238 YASAMFTLWPGDVIYTGTPSGVSA-------IQAGDRIEVSIERIGAMSVTIAD 284


>UniRef50_Q6BTK5 Cluster: Similar to CA3735|IPF5534 Candida albicans
           IPF5534; n=2; Ascomycota|Rep: Similar to CA3735|IPF5534
           Candida albicans IPF5534 - Debaryomyces hansenii (Yeast)
           (Torulaspora hansenii)
          Length = 208

 Score =  121 bits (292), Expect = 2e-26
 Identities = 74/208 (35%), Positives = 105/208 (50%), Gaps = 9/208 (4%)

Query: 81  LNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKL-KMDVSKAVVCEIELTVVIGKK 138
           +NY  H +E  L PP  P IF K P T VG  N+ I + K+        E E  VVI K 
Sbjct: 1   MNYMKHIQEGSLPPPPKPQIFYK-PRTSVGDHNEAIAIPKIAQENQCDYEGEFCVVIVKT 59

Query: 139 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNK----KISQLLLGKAMDTFCPIGPWIVTSD 194
              +    A +YV GY +  D+ A  W+ +      I Q    K+ D + P+GP + ++ 
Sbjct: 60  GKHIKEEDALNYVAGYIVGDDVSARIWQYHPDYSGNIPQWYYSKSFDRYAPLGPALFSTR 119

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
            I NP  L ++  ING  +Q +NT+  +  I  IIA LS   TL  G +I+TGTP GVG 
Sbjct: 120 VIKNPHTLQLQTRINGELRQDANTDDLLFNIQKIIAFLSQGTTLEQGTVIMTGTPSGVGA 179

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282
                 +L+ GD++   IE IGT   ++
Sbjct: 180 VSG--RYLKDGDLVEISIEQIGTLSHKI 205


>UniRef50_A0Y9R8 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Gammaproteobacteria|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           marine gamma proteobacterium HTCC2143
          Length = 223

 Score =  120 bits (290), Expect = 3e-26
 Identities = 75/210 (35%), Positives = 107/210 (50%), Gaps = 12/210 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++CVG NY DH +E     P+ P +F K  +  V     I +  D       E+E+ V+
Sbjct: 23  KIVCVGRNYADHAKELNNPIPDRPLLFIKPSTAAVDMLLPINIPTDRG-CCHHELEMAVL 81

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 192
           IGK++S V S  A D ++G  +  D+   D +   K         KA D  CP+ P+   
Sbjct: 82  IGKRSSSVSSVEAKDAIVGVGLGLDLTLRDLQDELKAKGEPWERAKAFDGSCPLSPFSSV 141

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252
            D   + QNLN+    NG  +Q  NT   +  + D+IA +S   TLLPGDIILTGTP GV
Sbjct: 142 GDI--DQQNLNITLLRNGTVQQSGNTRDMLFPVADLIADISRSFTLLPGDIILTGTPAGV 199

Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           G        L PGD IT+++ ++ T  T +
Sbjct: 200 GP-------LYPGDTITAQLGDLVTVNTTI 222


>UniRef50_P76004 Cluster: Uncharacterized protein ycgM; n=41;
           Gammaproteobacteria|Rep: Uncharacterized protein ycgM -
           Escherichia coli (strain K12)
          Length = 219

 Score =  119 bits (287), Expect = 7e-26
 Identities = 72/200 (36%), Positives = 102/200 (51%), Gaps = 6/200 (3%)

Query: 63  GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122
           G  L  PV    KV+CVG NY  H +E     PE P +F K  + +      + +  D  
Sbjct: 9   GALLDYPV---SKVVCVGSNYAKHIKEMGSAVPEEPVLFIKPETALCDLRQPLAIPSDFG 65

Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLL-LGKAM 180
            +V  E+EL V+IG    +    H    + GY +A D+   D + K KK  Q     KA 
Sbjct: 66  -SVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWEKAKAF 124

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           D  CP+  +I  ++  G+PQN  +  S+NG Q+Q+  T   IHKI  +IA +S   TL  
Sbjct: 125 DNSCPLSGFIPAAEFTGDPQNTTLSLSVNGEQRQQGTTADMIHKIVPLIAYMSKFFTLKA 184

Query: 241 GDIILTGTPGGVGVYRNPPE 260
           GD++LTGTP GVG  ++  E
Sbjct: 185 GDVVLTGTPDGVGPLQSGDE 204


>UniRef50_Q7VGX9 Cluster: Putative uncharacterized protein; n=1;
           Helicobacter hepaticus|Rep: Putative uncharacterized
           protein - Helicobacter hepaticus
          Length = 312

 Score =  118 bits (284), Expect = 2e-25
 Identities = 78/234 (33%), Positives = 121/234 (51%), Gaps = 12/234 (5%)

Query: 61  LSGITLKAPV-HGNDKVLCVGLNYKDHCEEQKLTPPEL-------PFIFNKFPSTVVGPN 112
           L+ ITL AP+      V+C+G+NY +H +E      E+          F+K  +     N
Sbjct: 82  LADITLLAPIPKPKQDVICLGINYLEHAKESAAYKNEIFDQKRENAVYFSKRVNYATPHN 141

Query: 113 DTIKLKMDVSKAVVCEIELTVVIGKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKNKKI 171
             I L  ++++ +  E+EL VV+G    K  +     D + GYTI  DI + D ++  K 
Sbjct: 142 APIPLHSNLTQKLDYEVELGVVLGSHLYKPKNMQEVIDSIFGYTIINDISSRDIQQKHK- 200

Query: 172 SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIAR 231
            Q  +GK+++   P+GP IV++  I + QNL +K  +NG  +Q S+T+  I  I   +  
Sbjct: 201 -QWYMGKSLEGSLPMGPCIVSARSI-DAQNLAIKSYVNGELRQDSHTSLMICNITAALYE 258

Query: 232 LSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEEF 285
           LS+   L    II  GTP GVG+  NPP FL   D I  EI++IG+    V ++
Sbjct: 259 LSHYCMLQAASIISMGTPSGVGMGFNPPRFLSNNDEIVCEIQHIGSLRNVVIDY 312


>UniRef50_Q2S2N6 Cluster: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1;
           Salinibacter ruber DSM 13855|Rep: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Salinibacter ruber (strain DSM 13855)
          Length = 220

 Score =  118 bits (284), Expect = 2e-25
 Identities = 62/189 (32%), Positives = 103/189 (54%), Gaps = 4/189 (2%)

Query: 67  KAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV 126
           ++P     K+LC+G NY DH  E     P+ P +F K  S +V     ++L    S+ V 
Sbjct: 8   RSPPVSVGKLLCIGRNYADHAAEMDRAVPDEPMVFLKPASALVRSGGAVRLPPQ-SQDVH 66

Query: 127 CEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ--LLLGKAMDTFC 184
            E+EL  V+G +   +  S A D+V GY +  D+ A D +   K  +    + K  DTF 
Sbjct: 67  HEVELVAVVGTEGKNIPRSAALDHVAGYAVGLDMTARDLQAEAKERRHPWSVAKGFDTFA 126

Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244
           P+GP I  ++ + + Q+L ++ ++N   +Q+++T   I  + D++   S++ TL PGD++
Sbjct: 127 PLGP-IQPAEAVDDVQDLTLRLTVNDETRQEASTRHQIFPVRDLVHYCSHIFTLSPGDLL 185

Query: 245 LTGTPGGVG 253
            TGTP GVG
Sbjct: 186 YTGTPSGVG 194


>UniRef50_A4WBF8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=2; Gammaproteobacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Enterobacter sp. 638
          Length = 219

 Score =  118 bits (284), Expect = 2e-25
 Identities = 73/193 (37%), Positives = 99/193 (51%), Gaps = 6/193 (3%)

Query: 63  GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122
           G  L  PV    KV+CVG NY  H +E     P+ P +F K  + +      + L   + 
Sbjct: 9   GALLDYPV---SKVVCVGSNYAKHIQEMGSAVPDEPVLFIKPETALCDIRQPLALPQGLG 65

Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLL-LGKAM 180
            +V  E+EL V+IG    +    H    + GY IA D+   D + K KK  Q     K  
Sbjct: 66  -SVHHEVELAVLIGATLRQASEEHVQKAIAGYGIALDLTLRDVQGKMKKAGQPWEKAKGF 124

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           D  CPI  +I T+D   +PQN ++   +NG  +Q+ NT   IHKI  +IA +S   TL P
Sbjct: 125 DNSCPISGFIPTADFKADPQNTSLSLKVNGDIRQQGNTADMIHKILPLIAYMSRYFTLKP 184

Query: 241 GDIILTGTPGGVG 253
           GD+ILTGTP GVG
Sbjct: 185 GDVILTGTPEGVG 197


>UniRef50_P73637 Cluster: 5-oxo-1,2,5-tricarboxilic-3-penten acid
           decarboxilase/isomer; n=10; Bacteria|Rep:
           5-oxo-1,2,5-tricarboxilic-3-penten acid
           decarboxilase/isomer - Synechocystis sp. (strain PCC
           6803)
          Length = 276

 Score =  118 bits (283), Expect = 2e-25
 Identities = 72/208 (34%), Positives = 101/208 (48%), Gaps = 12/208 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++ VG NY+ H  E     P  P +F K PS +    + I      S+ V  E EL V+
Sbjct: 59  KIVAVGRNYRAHAAELGNDVPAEPLLFFKPPSAIAADQEEIVYPSQ-SQRVDYEGELAVI 117

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IGK+   +    A   + GYTIA DI A D ++    SQ    K  D FCP+GPW+V   
Sbjct: 118 IGKQVKDITEEEAASAIWGYTIANDITARDLQRQD--SQWTRAKGFDGFCPLGPWVVR-- 173

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
            I    +L    +     +Q +  +  +   P +++ +S VMTL PGD+ILTGTP G+  
Sbjct: 174 HIDPEAHLETTVNDEETPRQATAISDMVFTPPVLVSYISRVMTLYPGDVILTGTPEGISA 233

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282
                  LQ GD +  EIE IG     +
Sbjct: 234 -------LQVGDKVEVEIEGIGNLTNTI 254


>UniRef50_A5V8P5 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 343

 Score =  117 bits (282), Expect = 3e-25
 Identities = 73/188 (38%), Positives = 99/188 (52%), Gaps = 7/188 (3%)

Query: 98  PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 157
           PF F K  S+++GP D + +  D S+ +  E+EL VVIGK A +V    A D+V GY + 
Sbjct: 137 PFAFLKPFSSILGPFDDLAVPAD-SEQLDWELELGVVIGKPARRVGRDRALDHVAGYVVV 195

Query: 158 QDIGATDWEKNKKISQLLL----GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213
            DI   D      + QL L    GK+     P+GP IV +  + +PQ L +   +NG   
Sbjct: 196 NDISVRDHLYRPDVPQLGLDWVSGKSGPGMLPMGPLIVPAAFVADPQQLMITLKLNGEVM 255

Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273
           Q  +T   I  I  +I   S  M LLPGDII TG+P G G +     FL+PGDV+   IE
Sbjct: 256 QHESTADMIFPIARLIEAFSVHMQLLPGDIICTGSPSGNGTHFG--RFLRPGDVMEGTIE 313

Query: 274 NIGTFETR 281
            +GT   R
Sbjct: 314 GLGTQRNR 321


>UniRef50_Q8NQY2 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Corynebacterium|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Corynebacterium glutamicum (Brevibacterium flavum)
          Length = 268

 Score =  116 bits (280), Expect = 5e-25
 Identities = 85/222 (38%), Positives = 114/222 (51%), Gaps = 17/222 (7%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEE--QKLTPPELPFIFNKFPSTVVGPNDTIKLK 118
           L  + L AP+  + KV+ +G NY DH  E  +K      P +F K P+ V GP   I++ 
Sbjct: 49  LKDVRLLAPMLPS-KVVAIGRNYADHVAEVFKKSAESLPPTLFLKPPTAVTGPESPIRIP 107

Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGK 178
              +K V  E EL VVIGK    V +      VLG+TI  D+ + D +      Q    K
Sbjct: 108 SFATK-VEFEGELAVVIGKPCKNVKADDWKSVVLGFTIINDVSSRDLQFAD--GQWARAK 164

Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCSI--NGVQ--KQKSNTNQFIHKIPDIIARLSN 234
            +DTF PIGPWI T     +  NL +K  +  +G    KQ SN+NQ I K+ +II  ++ 
Sbjct: 165 GIDTFGPIGPWIETDINSIDLDNLPIKARLTHDGETQLKQDSNSNQMIMKMGEIIEFITA 224

Query: 235 VMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
            MTLLPGD+I TG+P G        E +  GD I  EI  IG
Sbjct: 225 SMTLLPGDVIATGSPAGT-------EAMVDGDYIEIEIPGIG 259


>UniRef50_A7BDZ2 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 255

 Score =  116 bits (279), Expect = 7e-25
 Identities = 84/222 (37%), Positives = 112/222 (50%), Gaps = 14/222 (6%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           L  + L +PV    KV+ +G NY D        P   P IF K  ++VVGP+D I +   
Sbjct: 45  LDEVRLLSPVIPRSKVVGIGDNYSDTPIPADERPE--PPIFLKANTSVVGPDDPIAIPA- 101

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
            S AV  E EL +VI   A  V    A   +LGYTIA D  A D       S+   GK+ 
Sbjct: 102 WSNAVAFEGELAIVIKSLAKDVSVEDAPQMILGYTIANDATARDAMTGGPWSR---GKSF 158

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           D+ CP+GPWI T D   +  NL ++  +NG   Q S+T   I    ++++ LS+ MTLLP
Sbjct: 159 DSACPLGPWI-TVDPALDVTNLAIRSYLNGEIAQDSSTAHMIWNPFELVSYLSHQMTLLP 217

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GD+I TG P G        E +  GD +  EIE IG+    V
Sbjct: 218 GDVIATGAPAGA-------EIVHAGDRVEIEIEGIGSLTNPV 252


>UniRef50_A2QFQ2 Cluster: Remark: ORF contains 1 frameshift; n=3;
           Trichocomaceae|Rep: Remark: ORF contains 1 frameshift -
           Aspergillus niger
          Length = 296

 Score =  115 bits (276), Expect = 2e-24
 Identities = 67/215 (31%), Positives = 110/215 (51%), Gaps = 5/215 (2%)

Query: 73  NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKL-KMDVSKAVVCEI-E 130
           N+ + CVGLNY+ H +E  L  P  P ++ K P+ +  P++TI + +   S     E  E
Sbjct: 64  NNSIYCVGLNYRSHAKEANLNVPANPPVWTKPPAALASPDETIPISRFCASHLPDWEAGE 123

Query: 131 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE-KNKKISQLLLGKAMDTFCPIGPW 189
           L  V  ++   V    A  Y+LGYT+  D+    ++   +   Q    KA D F PIGP 
Sbjct: 124 LVFVTSRECRDVTPEQASQYILGYTVGNDLSCRFFQLPEQSGGQFFYAKAFDKFAPIGPV 183

Query: 190 IVTSDEIGNPQ-NLNVKCSINGVQKQKSNTNQFIHKIPD-IIARLSNVMTLLPGDIILTG 247
           +V+ D     + +  +   INGV KQ +   + +   P+ +++ +S   T+    +++TG
Sbjct: 184 LVSPDVFAKTRTSATLVTRINGVVKQDTVIGKDMIFSPERVLSWMSQSTTIPAYTVVMTG 243

Query: 248 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           TP G GV++ P + L+ GD I  EI  +GT +  V
Sbjct: 244 TPAGAGVFQTPRQLLKDGDHIEVEISGLGTLKNVV 278


>UniRef50_Q01NL2 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Solibacter usitatus Ellin6076|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Solibacter usitatus (strain Ellin6076)
          Length = 252

 Score =  114 bits (275), Expect = 2e-24
 Identities = 77/223 (34%), Positives = 106/223 (47%), Gaps = 15/223 (6%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           LS + L  P     K+L VGLNYK H   +    P  P +F K  S +  P D I+L  D
Sbjct: 43  LSDVKLLYPCEAG-KILAVGLNYKSHLGSRP--QPAHPEMFYKPISALQNPGDPIELPRD 99

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLLLGKA 179
            +  V  E E+ VV+G          A D V G T   D+    W+   KK  Q    K 
Sbjct: 100 ATD-VHSEGEMVVVVGGYLRNASVDEAADAVFGVTCGNDVSDRSWQHGEKKDLQWWRAKG 158

Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
            DTF P+GP IV+  + G    L ++  ING   QK  T+  I  IP +++ +S  +TL 
Sbjct: 159 SDTFAPLGPAIVSGVDYGK---LLLQTRINGETVQKQFTSDLIFDIPTVLSWISGWVTLF 215

Query: 240 PGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           PGD++ TGTPG           + PGD++  E+E +G     V
Sbjct: 216 PGDLVYTGTPGNT-------RKMSPGDLVEVELEGVGVLSNPV 251


>UniRef50_Q6P587 Cluster: Fumarylacetoacetate hydrolase
           domain-containing protein 1; n=21; Eumetazoa|Rep:
           Fumarylacetoacetate hydrolase domain-containing protein
           1 - Homo sapiens (Human)
          Length = 224

 Score =  114 bits (275), Expect = 2e-24
 Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 4/187 (2%)

Query: 76  VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 135
           ++CVG NY DH  E +      P +F K PST   P  +  L    ++ +  E+EL VV+
Sbjct: 20  IVCVGRNYADHVREMRSAVLSEPVLFLK-PSTAYAPEGSPILMPAYTRNLHHELELGVVM 78

Query: 136 GKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTFCPIGPWIVTS 193
           GK+   V  + A DYV GY +  D+ A D   E  KK     L K+    CP+  + V  
Sbjct: 79  GKRCRAVPEAAAMDYVGGYALCLDMTARDVQDECKKKGLPWTLAKSFTASCPVSAF-VPK 137

Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
           ++I +P  L +   +NG  +Q+  T+  I  IP II+ +S ++TL  GDIILTGTP GVG
Sbjct: 138 EKIPDPHKLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIITLEEGDIILTGTPKGVG 197

Query: 254 VYRNPPE 260
             +   E
Sbjct: 198 PVKENDE 204


>UniRef50_Q0LZE6 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Caulobacter sp. K31|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Caulobacter sp. K31
          Length = 293

 Score =  113 bits (273), Expect = 4e-24
 Identities = 79/283 (27%), Positives = 124/283 (43%), Gaps = 12/283 (4%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXX 60
           M+LL F    +  +  G   G+ V+D+    P LP  +  LL                  
Sbjct: 1   MRLLSFELNGAPAV--GVRLGEEVIDLGAAAPDLPRDIQALLAAGPEALAAAERAAAAAP 58

Query: 61  ------LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT 114
                 L+G+    P+   DK++ +G  Y  H  E K      P +F + P ++V  N  
Sbjct: 59  GHARHPLAGVRHLVPIPRPDKIIGLGKTYMKHVAEMKAESSSFPGMFLRVPDSLVAHNQP 118

Query: 115 IKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL 174
           I  + + S  +  E EL VVIG+    +   +A  +V GY    D     +  N   S +
Sbjct: 119 I-WRPEASDTLDYEGELMVVIGQGGRMISRENALKHVAGYACHNDGSVRAY--NYIPSAV 175

Query: 175 LLGKAMDTFCPIGPWIVTSDEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLS 233
             GK        GP IVT+DE+    + L +   +NG  +Q ++  +    +  ++  +S
Sbjct: 176 TAGKNFLNTGGFGPEIVTADELPPGCKGLRLTTHVNGDLRQSADVAELHWDVAHLVHLMS 235

Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
            + TL PGD+I TGTP G       P++L PGDV+  EIE +G
Sbjct: 236 TIFTLYPGDLIATGTPSGCAAASANPQWLVPGDVVRVEIEGVG 278


>UniRef50_Q5LT14 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Silicibacter pomeroyi|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Silicibacter pomeroyi
          Length = 281

 Score =  113 bits (271), Expect = 6e-24
 Identities = 64/225 (28%), Positives = 108/225 (48%), Gaps = 7/225 (3%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFI--FNKFPSTVVGPNDTIKLK 118
           L  +    P+    K+LC G+NY+       + PP+   +  F++ P T+VG    +++ 
Sbjct: 58  LDSLVWLPPIPAPGKILCAGMNYRKPYPVAGVAPPDPGHVVLFSRHPQTLVGHGAMLEMP 117

Query: 119 MDVS-KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG 177
              + ++   E E+  VIG+    +    A  +VLGY+   +     W K+     +  G
Sbjct: 118 QGAAAESFDFEGEIVAVIGQPGRHIAPEAALGHVLGYSAMNEGSVRGWMKHS----VHAG 173

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           K        GPWI T+DE G+   + ++  +NG   Q  +    I  + ++IA +S++  
Sbjct: 174 KNFHASGSWGPWITTADEAGDIAGMTLETRVNGTPMQSDSGAGMIFGLAELIAYISHIQP 233

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           L  GDII TG+P G G  R PP FL+ GD +   +  +GT +  V
Sbjct: 234 LEAGDIIATGSPDGTGGSRTPPAFLRSGDRVAVTVGGVGTLKNTV 278


>UniRef50_Q28U26 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=1; Jannaschia sp. CCS1|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Jannaschia sp. (strain CCS1)
          Length = 271

 Score =  112 bits (270), Expect = 8e-24
 Identities = 73/226 (32%), Positives = 110/226 (48%), Gaps = 10/226 (4%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           +T   PV    K+LCV LNY DH +E     PE P +F K    ++     I+    +++
Sbjct: 48  VTALPPVTPTAKILCVALNYVDHAKEANQPVPETPIVFFKTFDAMIAGGAPIRAPRMITQ 107

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKK--ISQL--LLGKA 179
            +  E EL ++IGK+   +  + A+D++ G T   D+ A D  K K    S L    GK 
Sbjct: 108 -LDYEGELALIIGKRGFDIAKTDAWDHIAGVTTLNDVSARDIFKVKAGAASHLDWFSGKC 166

Query: 180 MDTFCPIGPWIVTSDEIGNPQNLN---VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236
           ++   PIGP +     I +        ++C +NG  +Q +     I  IP +IA +S+ +
Sbjct: 167 LNQSTPIGPEVFPLSAIEDDLKAGTTRIRCLVNGEVRQDAPVADMIFDIPTMIAFISSRI 226

Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
            L PGDII TGTP GVG       +L  GDV+  E+  +   E  V
Sbjct: 227 PLNPGDIIATGTPPGVGA--GTDRYLSKGDVVRVEVTGLPPMENTV 270


>UniRef50_A5V6J4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Sphingomonas wittichii RW1
          Length = 329

 Score =  112 bits (269), Expect = 1e-23
 Identities = 66/190 (34%), Positives = 96/190 (50%), Gaps = 7/190 (3%)

Query: 98  PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 157
           P++F K  +TV G NDT+ L  + +K    E+EL VVIG+   ++    A ++V GY I 
Sbjct: 139 PYVFTKPITTVAGANDTLILPANTTKPD-WELELAVVIGRGGIRIPREAAMEHVAGYAIV 197

Query: 158 QDIGATDWEKNKKISQL----LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213
            D+ A D         L    L  K  + F P GP++V +  I +P  L ++ S+ G   
Sbjct: 198 NDVSARDLIPRTDYKLLGTDWLRSKGQEGFLPFGPYMVPARFIADPYALRIRLSVEGQMM 257

Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273
           Q   T   +  I   I  +S    LLPGD+I TG+P G G + N   FLQ GD++  EI+
Sbjct: 258 QDETTADMMFDIARQIEYISRYSRLLPGDVICTGSPAGNGTHYN--RFLQDGDLMIGEID 315

Query: 274 NIGTFETRVE 283
            +G    R E
Sbjct: 316 GLGAQRIRCE 325


>UniRef50_Q9LUR3 Cluster: Isomerase-like protein; n=5; rosids|Rep:
           Isomerase-like protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 224

 Score =  111 bits (268), Expect = 1e-23
 Identities = 66/181 (36%), Positives = 102/181 (56%), Gaps = 4/181 (2%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++ VGLNY  H +E     P+ P +F K  S+ +    TI++   +  ++  E+EL VV
Sbjct: 15  KIVGVGLNYASHAKELGNALPKDPIVFLKPTSSYLENGGTIEIPHPLD-SLHHEVELAVV 73

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVT 192
           IG+KA  V    A +Y+ GY +A D+ A + + +   S L   L K  DTF PI   ++ 
Sbjct: 74  IGQKARDVPERLAMNYIGGYALALDMTARELQVSAMASGLPCTLAKGQDTFTPISS-VLP 132

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252
              + +P NL +   ++   +QK  T   I K+P +I+ +S+VMTL  GD+ILTGTP G+
Sbjct: 133 KAMVLDPNNLELWLKVDDETRQKGWTKDMIFKVPYLISYISSVMTLFKGDVILTGTPEGI 192

Query: 253 G 253
           G
Sbjct: 193 G 193


>UniRef50_Q8G4X7 Cluster: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the
           fumarylacetoacetate hydrolase family; n=6;
           Bifidobacterium|Rep: Possible
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase in the
           fumarylacetoacetate hydrolase family - Bifidobacterium
           longum
          Length = 292

 Score =  111 bits (267), Expect = 2e-23
 Identities = 79/223 (35%), Positives = 112/223 (50%), Gaps = 21/223 (9%)

Query: 63  GITLKAPVHGNDKVLCVGLNYKDHCE-------EQKLTPPELPFIFNKFPSTVVGPNDTI 115
           GI L +PV  + KV  +  NY+ H +        +    PE   IF K  ++V+GP+D I
Sbjct: 73  GIRLLSPVIPS-KVYGLAKNYEAHAQFMHEAGHSEIAHAPEDMVIFTKPSTSVIGPDDPI 131

Query: 116 KLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL 175
                 SK +  E E+ VV+G+ A  V   +A DYVLG+T   D+   D +         
Sbjct: 132 VYPA-CSKDMNFEPEVAVVMGRIAKNVTVENAMDYVLGFTCVNDVTLRDLQGIDPT--WT 188

Query: 176 LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSING--VQKQKSNTNQFIHKIPDIIARLS 233
             K  DT CP+GPWIV  D++ + ++  +  ++NG  V      T   IH IP+ IA +S
Sbjct: 189 RAKGFDTSCPLGPWIVMRDDL-DWKDAKISFTLNGEDVPMASGTTANLIHGIPEQIAAIS 247

Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
           +  TLLPGD+I+TGTP   G        L PGD     +E IG
Sbjct: 248 SFSTLLPGDVIMTGTPNASG-------HLDPGDETIVHVEGIG 283


>UniRef50_Q2G539 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=5; Bacteria|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Novosphingobium aromaticivorans (strain DSM 12444)
          Length = 296

 Score =  111 bits (266), Expect = 3e-23
 Identities = 65/208 (31%), Positives = 108/208 (51%), Gaps = 12/208 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++CV LNY    +E     P  P  F K P T +  +    ++ +  K +  E E+ +V
Sbjct: 47  KIICVHLNYHSRVQEFITKLPPAPTYFQK-PLTALNTHKGAIVRPERCKWLNYEGEIAIV 105

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           IGK    +  + A DY+LGY++A D G  D+ ++     +L  K  DT CPIGP +VT  
Sbjct: 106 IGKTCRNISPAEAGDYILGYSVANDYGLHDF-RDTDAGSMLRVKGSDTLCPIGPGLVTGW 164

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
           +  +     ++  +NGV KQ+ NT+     +  ++A ++  +TL PGD++L+GTP     
Sbjct: 165 DFRDKM---IRTYVNGVLKQEDNTSNMEWDMHYLVADIARTITLEPGDVLLSGTPAN--- 218

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRV 282
              P   +Q GDV+  E++ +G     +
Sbjct: 219 -SRP---VQIGDVVEVEVDGLGRLSNTI 242


>UniRef50_Q6N2Q7 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=11;
           Bradyrhizobiaceae|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Rhodopseudomonas palustris
          Length = 233

 Score =  110 bits (265), Expect = 3e-23
 Identities = 68/210 (32%), Positives = 101/210 (48%), Gaps = 11/210 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           ++ CVG NY +H  E      + PF F K    V     TI     ++K +  E+EL V 
Sbjct: 29  RIWCVGRNYLEHVREMGNDERQPPFFFAKHADMVTPDGATIPYP-PLTKDLHHEVELVVA 87

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTFCPIGPWIVT 192
           +      +    A D+V GY +  D+   D +    KK     +GK+ D   P G  +  
Sbjct: 88  LKSGRLNIPVERALDHVWGYAVGIDLTRRDLQIASRKKEQPWEIGKSFDASAPCGA-LRP 146

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252
           + EIG+P    +  S+NG ++Q  + ++ I  +P+IIA+LS  + L  GDII+TGTP GV
Sbjct: 147 ASEIGHPATGKIWLSVNGTERQTGDLSEMIWNVPEIIAKLSAQVELAAGDIIMTGTPAGV 206

Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRV 282
                    L PGD I   I+ IGT    +
Sbjct: 207 AA-------LSPGDAIACGIDGIGTLNVTI 229


>UniRef50_A5V6X8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           Delta-isomerase; n=1; Sphingomonas wittichii RW1|Rep:
           5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
           Sphingomonas wittichii RW1
          Length = 325

 Score =  110 bits (264), Expect = 5e-23
 Identities = 66/199 (33%), Positives = 103/199 (51%), Gaps = 8/199 (4%)

Query: 88  EEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHA 147
           ++ K  PP  P++F K  +   G  D I L   + + +  E EL VVIG     +  + A
Sbjct: 121 DQGKQLPPLRPYMFGKI-NVPTGAFDDIILPPGMER-IDWEAELMVVIGTPGLAIRPAEA 178

Query: 148 FDYVLGYTIAQDIGATD--WEKNKKI--SQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLN 203
             ++ GY    D+   D  W +++    S  L GK+ D+F P+GP +     + +  +L 
Sbjct: 179 HRHIAGYMTGNDVSCRDRTWREDRPTIRSDWLGGKSYDSFAPLGPLLTPRQFVPDHADLA 238

Query: 204 VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQ 263
           ++  +NG  KQ  N+      I + I   S++MTLLPGD+I TGTP G G  R   EFL+
Sbjct: 239 IRLWVNGELKQDGNSRDMTFGIEEQIEYASSMMTLLPGDVIATGTPAGTGQERG--EFLK 296

Query: 264 PGDVITSEIENIGTFETRV 282
            GD++ +E+E+ G    RV
Sbjct: 297 EGDIVETEVESCGRQRNRV 315


>UniRef50_A0HJM1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Comamonas testosteroni KF-1
          Length = 289

 Score =  110 bits (264), Expect = 5e-23
 Identities = 65/189 (34%), Positives = 99/189 (52%), Gaps = 9/189 (4%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVG--PNDTIKLKMD-VSKAV 125
           P+H   ++ CVG NY+DH +E   T  E PF F K     V      T ++    +++ +
Sbjct: 81  PIH---RIYCVGRNYEDHAKEMGFTGREPPFFFMKPADATVALEAGSTGQVAYPTLTQNL 137

Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDW--EKNKKISQLLLGKAMDTF 183
             EIEL V IGK    + ++ A  Y+ GY +  D+   D   E  K+     +GKA +  
Sbjct: 138 HHEIELVVAIGKAGKNIKAADALQYIYGYAVGLDMTRRDLQNEMKKQGRPWCIGKAFEQS 197

Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243
            PIGP I  +D+ G+  N  +   +NG  +Q+S+ ++ I  I + I  LS+   L PGD+
Sbjct: 198 APIGP-ITPADQAGDIANAEISLQVNGDYRQRSHIHKLIWNIAETIEHLSSAWELQPGDL 256

Query: 244 ILTGTPGGV 252
           I+TGTP GV
Sbjct: 257 IMTGTPEGV 265


>UniRef50_Q1DXV6 Cluster: Putative uncharacterized protein; n=2;
           Eurotiomycetidae|Rep: Putative uncharacterized protein -
           Coccidioides immitis
          Length = 327

 Score =  110 bits (264), Expect = 5e-23
 Identities = 68/217 (31%), Positives = 112/217 (51%), Gaps = 7/217 (3%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-C 127
           PV G + ++CVGLNY++H  E  L  P  P ++ K P  +  P+  I +     K+    
Sbjct: 113 PVTGIN-IICVGLNYRNHANEASLPIPTCPPMWYKAPPALADPDSEIPVPPQAQKSFPDF 171

Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187
           E ELT+V+      + +S A  ++LGYTI  D+ A  +++     Q    K  D F P+G
Sbjct: 172 EGELTIVLRNTIKSISASEATSHILGYTIGNDLTARFFQRACG-GQYTHAKGFDNFAPLG 230

Query: 188 PWIVTSDEIGNPQNLN--VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
           P +V    + +P + +  +   +NG   Q S  + FI  + ++++ LS   T+  G  I+
Sbjct: 231 PRLV-HPSVFSPSDASRRITTRVNGRVVQDSPFD-FIFPVDELVSFLSEGTTIPAGTAIM 288

Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           TGTP GVG +++P   LQ GD +  E++ IG     +
Sbjct: 289 TGTPAGVGWFQDPKCPLQHGDAVEVEVQPIGVLRNTI 325


>UniRef50_Q397B1 Cluster: Fumarylacetoacetate (FAA) hydrolase;
           n=123; Proteobacteria|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Burkholderia sp. (strain 383) (Burkholderia
           cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 252

 Score =  109 bits (261), Expect = 1e-22
 Identities = 69/208 (33%), Positives = 103/208 (49%), Gaps = 12/208 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133
           +V CVG NY DH  E    P  E PF F K    +V  + T+     ++  +  EIEL V
Sbjct: 47  RVFCVGRNYADHAREMGADPDREPPFFFTKPADAIVPASGTVAYP-PLTNDLHHEIELVV 105

Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLL-LGKAMDTFCPIGPWIV 191
            IGK    +D + A  +V GY +  D+   D +   KK+S+     K  D   P+   + 
Sbjct: 106 AIGKDGRAIDPADALSHVWGYGVGIDLTRRDLQAEAKKLSRPWDWAKGFDASGPVTA-LR 164

Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251
            +   G+P    +  ++NG  +Q+ +    I  +PD+IA +S  + L  GD+I TGTP G
Sbjct: 165 AASATGHPATGRIWLAVNGDTRQQGDLADMIWAVPDVIAYVSRSVELKAGDLIFTGTPAG 224

Query: 252 VGVYRNPPEFLQPGDVITSEIENIGTFE 279
           VG        LQPGD +T  ++ + TFE
Sbjct: 225 VGA-------LQPGDRVTGGVDGVATFE 245


>UniRef50_A3Q487 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Mycobacterium sp. JLS|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Mycobacterium sp. (strain JLS)
          Length = 265

 Score =  109 bits (261), Expect = 1e-22
 Identities = 72/228 (31%), Positives = 110/228 (48%), Gaps = 8/228 (3%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPNDTIKLKM 119
           L  + L  P+     V+ VG+NY  H E+  +T  P+    F K  + ++G  D +   +
Sbjct: 39  LDDVRLLPPITPTSTVVGVGMNYWSHLEKLGVTERPKSTLGFLKPRAAIIGHGDVLANPV 98

Query: 120 DVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLG-K 178
            +++ +  E+EL VV+ +  S        + VLGYT+  D+ A D          L   K
Sbjct: 99  -ITEQLDFEVELVVVLAQSVSH-PGGRPTEAVLGYTVGNDVSARDAAVPMSGGLDLFSIK 156

Query: 179 AMDTFCPIGPWIVTSDEIGNPQNLNVKCS--INGVQKQKSNTNQFIHKIPDIIARLSNVM 236
           A+    P+GPWI T DE G    ++V  S  +NG Q+Q   T + I  I + +  +   M
Sbjct: 157 ALGGTTPVGPWITTKDEFGGSGQIDVGISLRVNGEQRQHDRTGKMIFSIDECLDYVVARM 216

Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
            L  GDI+ TGT  GVG       +LQ GDV+ +E+E +G     V E
Sbjct: 217 PLAAGDIVFTGTTHGVGF--EDGRYLQAGDVVEAEVEGVGVLRNIVGE 262


>UniRef50_Q7VXR8 Cluster: Putative hydrolase; n=1; Bordetella
           pertussis|Rep: Putative hydrolase - Bordetella pertussis
          Length = 316

 Score =  108 bits (259), Expect = 2e-22
 Identities = 62/192 (32%), Positives = 102/192 (53%), Gaps = 7/192 (3%)

Query: 96  ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASK-VDSSHAFDYVLGY 154
           ++P  F K  S V+ P+D+   +     A   E+E+  V+G           A ++V GY
Sbjct: 126 DMPAGFIKIAS-VMTPHDSAVARPCGVLAFDYEVEVAAVLGGPVPLGTPPERALEHVFGY 184

Query: 155 TIAQDIGATDWEKNKKISQLL-LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213
           T+  D+ A +W + +  +Q++ +GK      P+GPWIVT+DE+ +P  L +  S+NG  +
Sbjct: 185 TLFNDLSAREWARAEMKNQMIAMGKNFPGAGPLGPWIVTADEVPDPAQLELSLSVNGEPR 244

Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP---PEFLQPGDVITS 270
           Q  +  + I     +IA  S +  L  G++I +GTP G  + R P   P FL+PGD++ +
Sbjct: 245 QHGSCKEMIFTFAQLIAHWSRI-GLGAGELIASGTPEGGAISRKPDPAPFFLKPGDIVEA 303

Query: 271 EIENIGTFETRV 282
               IGT  TR+
Sbjct: 304 HCPQIGTLRTRI 315


>UniRef50_Q0K430 Cluster: 2-Keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=3; Burkholderiales|Rep: 2-Keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 /
           Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
           H16 / DSM 428 / Stanier337))
          Length = 301

 Score =  108 bits (259), Expect = 2e-22
 Identities = 60/163 (36%), Positives = 92/163 (56%), Gaps = 9/163 (5%)

Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL------LG-KAM 180
           E EL VVIGK    +    A D V GYTIA D+ A D  + +++          +G K  
Sbjct: 141 EAELAVVIGKACRNISPGDALDCVAGYTIANDLSARDNLRREQVDASSPFRFDWIGHKCF 200

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           +  CP+GP++  +  + +P+ L++K  +N   KQ SNT+  ++ + + IA LS  +TL P
Sbjct: 201 EGSCPLGPYLTPAAFVASPEALDIKLWVNDELKQNSNTSNHLYTVAEQIAYLSERLTLYP 260

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           GD++LTGTP GVG+      FL+ GD I   I+ +G  ET ++
Sbjct: 261 GDVLLTGTPAGVGM--ESGVFLKRGDSIRVWIDGLGELETSLQ 301


>UniRef50_UPI000023E361 Cluster: hypothetical protein FG10641.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG10641.1 - Gibberella zeae PH-1
          Length = 230

 Score =  107 bits (258), Expect = 2e-22
 Identities = 62/151 (41%), Positives = 81/151 (53%), Gaps = 3/151 (1%)

Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187
           E EL VVIG+ A  V    A +YVLGYT A DI +   +  +  SQ    K  D  CP+G
Sbjct: 73  EAELAVVIGRAAKNVTKEEAMEYVLGYTAANDISSRTSQFGQ--SQWCFSKGFDGSCPLG 130

Query: 188 PWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247
           P +V+ D + +P   N++        Q    +  I  IP +I+ LS   TLLPG +ILTG
Sbjct: 131 PALVSKDLVPDPSMFNIRGLKKDQVLQDCGADDLIFDIPTLISFLSQGTTLLPGTVILTG 190

Query: 248 TPGGVGVYRNPPEFLQPGDVITSEI-ENIGT 277
           TP GVGV R P   +  GD  + EI  +IGT
Sbjct: 191 TPAGVGVGRQPKVTISDGDEFSVEILPHIGT 221


>UniRef50_Q6N496 Cluster: Possible isomerase/decarboxylase; n=4;
           Alphaproteobacteria|Rep: Possible
           isomerase/decarboxylase - Rhodopseudomonas palustris
          Length = 329

 Score =  107 bits (257), Expect = 3e-22
 Identities = 65/187 (34%), Positives = 102/187 (54%), Gaps = 6/187 (3%)

Query: 99  FIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQ 158
           +I N+F  +V G N  +K     S  +  E+E  ++  +K + + ++ A +++ GYTI  
Sbjct: 143 YITNRF--SVRGTNTVVKWPR-YSAVMDYELEFGIITKRKGANISAAQAKNHIFGYTIFN 199

Query: 159 DIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKS 216
           D  A D ++ +   +L    GK+ D    IGPWIVT DEIG+P  LN++  +NG  + + 
Sbjct: 200 DFSARDAQRIEMEGRLGPAKGKSFDGGNVIGPWIVTPDEIGDPYRLNMEARVNGEVRSRG 259

Query: 217 NTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIG 276
            T   +    +IIA +S   TL+PG+ I +GT G  G       FL+ GDVI  E+E IG
Sbjct: 260 VTEGMLFSFEEIIAHVSRDETLMPGEFIGSGTVGN-GCGLELGWFLEHGDVIELEVEKIG 318

Query: 277 TFETRVE 283
             + +VE
Sbjct: 319 IPKNKVE 325


>UniRef50_Q7PYH5 Cluster: ENSANGP00000019097; n=2; Culicidae|Rep:
           ENSANGP00000019097 - Anopheles gambiae str. PEST
          Length = 232

 Score =  106 bits (255), Expect = 6e-22
 Identities = 64/188 (34%), Positives = 97/188 (51%), Gaps = 6/188 (3%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDT---IKLKMDVSKAVVCEIEL 131
           K++  G+NYK+         P+ P IF K  S   G   T   I++       +  E EL
Sbjct: 24  KIIGAGVNYKEILRLTNSPKPDAPVIFFKPISGSTGSTGTPPTIRIPRVFGGVINFEAEL 83

Query: 132 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPW 189
            V+IG++ + V +  A  YV GY +A D+   D+  + +   L   LGK  DT  P+   
Sbjct: 84  GVIIGRRCANVPTDQAMAYVGGYCLALDMTGMDFILDARPKGLPWCLGKGFDTSTPVSAL 143

Query: 190 IVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 249
           +  +D + NP ++ V C +NGV+KQ  +T   I  I ++IA +S  MTL   D++LTGTP
Sbjct: 144 VQRAD-LPNPDDVRVWCEVNGVRKQDDSTRNLIFPIAELIAYVSRFMTLEENDLLLTGTP 202

Query: 250 GGVGVYRN 257
            G G  R+
Sbjct: 203 AGAGPVRH 210


>UniRef50_A1HMI6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Thermosinus carboxydivorans Nor1|Rep:
           Fumarylacetoacetate (FAA) hydrolase - Thermosinus
           carboxydivorans Nor1
          Length = 295

 Score =  106 bits (254), Expect = 7e-22
 Identities = 67/189 (35%), Positives = 97/189 (51%), Gaps = 4/189 (2%)

Query: 68  APVHGN-DKVLCVGLNYKDHCEEQKLTPPEL-PFIFNKFPSTVVGPNDTIKLKMDVSKAV 125
           AP++ +  K+  +GLNY DH  +     P L P  F KF +T++GP + IK+ +  S+  
Sbjct: 80  APLYRHPSKIWGIGLNYVDHAGDLAEKAPTLAPASFAKFDTTIIGPGEEIKIPLQ-SEKT 138

Query: 126 VCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCP 185
             E EL ++ GKK   V+     + V G+T   D+ A D  +      L   K  DTF  
Sbjct: 139 TGESELAIIFGKKCKDVEEKDWLNVVAGFTTIIDMTAEDILRINP-RYLTRAKNFDTFLS 197

Query: 186 IGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
            GP +VT DEI +   LNV   ING    ++  +        +++  S V T+LPGDIIL
Sbjct: 198 FGPVLVTPDEIEDVNKLNVATVINGRIHARNVVSNMTFPPAYLVSFHSKVATMLPGDIIL 257

Query: 246 TGTPGGVGV 254
           TGTP  V +
Sbjct: 258 TGTPRAVQI 266


>UniRef50_A1HJ09 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=2; Ralstonia pickettii|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Ralstonia pickettii 12J
          Length = 250

 Score =  106 bits (254), Expect = 7e-22
 Identities = 63/187 (33%), Positives = 96/187 (51%), Gaps = 11/187 (5%)

Query: 94  PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 153
           PP+ P ++ K  +T +G    + L  DV   V     L V I   A++V + HA D++ G
Sbjct: 64  PPKAPILYLKPANTRIGHGHEVALPADVD-GVWAGACLGVAISCTATRVPAQHAADFIAG 122

Query: 154 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213
           YTI  D+        +     +  K  D FCP+GPW+V  D++ N   L++   ING  K
Sbjct: 123 YTIVNDLTVPHASYYRPA---IRHKCRDGFCPMGPWMVDRDDVPNADALDITVRINGEVK 179

Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273
           Q++NT+  +  I  ++A ++  MTL  GD++L G P       NPP   + GD I  +I 
Sbjct: 180 QRANTSTLVRPIAQLLADVTAFMTLESGDVLLVGMP------ENPP-LARAGDRIDIDIA 232

Query: 274 NIGTFET 280
           +IGT  T
Sbjct: 233 HIGTLTT 239


>UniRef50_Q70P92 Cluster: MelH protein; n=3; Cystobacteraceae|Rep:
           MelH protein - Melittangium lichenicola
          Length = 329

 Score =  105 bits (253), Expect = 1e-21
 Identities = 78/262 (29%), Positives = 122/262 (46%), Gaps = 16/262 (6%)

Query: 8   YKNSDGIRAGFLDGDNVVDINKEDPKLPSTLIELLKTNXXXXXXXXXXXXXXXLS--GIT 65
           +K    IR G +  D +V I    P   +TL   L                  L+   + 
Sbjct: 8   FKTGSEIRWGVVQRDRLVVI----PGQYATLAGFLGEGAAHARRLAAAPEGETLAVRDVE 63

Query: 66  LKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPF--IFNKFPSTVVGPNDTIKLKMDVSK 123
           L +PV     V+C G NY+ H  E    P    F   F K  S++   +  I +K +  +
Sbjct: 64  LLSPVTAPCNVVCQGQNYRSHMLEVGQDPEAKNFNQFFRKASSSLTSGHGDI-VKPERVR 122

Query: 124 AVVCEIELTVVIGKKAS---KVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAM 180
            +  EIEL +VIG+  S   +V+     ++V G  I  D+ A D +  +   Q    K+ 
Sbjct: 123 MLDYEIELGLVIGRPLSGPCRVERERLHEFVAGLVICNDVSARDIQLAE--GQWYKSKSF 180

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKC--SINGVQKQKSNTNQFIHKIPDIIARLSNVMTL 238
            TFCP GP++   D   N + +N+K   S+N   +Q SNT++ ++   + ++ LS VM L
Sbjct: 181 RTFCPAGPYLYLLDAEDNARVMNLKLHLSVNDQTRQDSNTSEMVYPPEETLSELSEVMDL 240

Query: 239 LPGDIILTGTPGGVGVYRNPPE 260
            PGD+++TGTP GV    N P+
Sbjct: 241 FPGDLVMTGTPRGVAAGHNAPK 262


>UniRef50_Q3INL8 Cluster: Probable
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 2;
           probable 5- oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase 2; n=1; Natronomonas pharaonis DSM
           2160|Rep: Probable 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase 2; probable 5-
           oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 2 -
           Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)
          Length = 319

 Score =  104 bits (249), Expect = 3e-21
 Identities = 58/188 (30%), Positives = 99/188 (52%), Gaps = 5/188 (2%)

Query: 96  ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 155
           E+P  +     +VV P +T++     S  +  E+EL  VIGK+   + +  A +Y+ GYT
Sbjct: 135 EMPVYYKSTADSVVAPGETVEWPA-YSSLMDYELELAAVIGKEGRDIPAEAADEYIAGYT 193

Query: 156 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQK 215
           I  D  A D +  +  ++L   K  D     GP++VT+D+  +P+   ++ ++NG    +
Sbjct: 194 IFNDFSARDIQGEEMQARLGPAKGKDFANAFGPYLVTADDF-DPETAEMRATVNGEVWSE 252

Query: 216 SNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG-GVGVYRNPPEFLQPGDVITSEIEN 274
               +  H   DI+A +S   TL PGD++ +GT G G G+     +FL+ GD ++  ++ 
Sbjct: 253 GTPGEMYHTFADIVAHVSQSETLYPGDVLGSGTVGEGCGLELG--QFLESGDTVSLFVDG 310

Query: 275 IGTFETRV 282
           IGT E  V
Sbjct: 311 IGTLENTV 318


>UniRef50_Q1AX83 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Rubrobacter xylanophilus DSM
           9941|Rep: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase - Rubrobacter xylanophilus (strain DSM
           9941 / NBRC 16129)
          Length = 295

 Score =  103 bits (248), Expect = 4e-21
 Identities = 65/211 (30%), Positives = 104/211 (49%), Gaps = 10/211 (4%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++ V L Y+   EE     P  P  F K P+ + G    ++     ++ +  E EL V+
Sbjct: 57  KIIAVHLTYRSRVEEYGARVPPEPSYFLKPPTALNGHRGVVRWPAG-TRFLNYEGELAVI 115

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSD 194
           +G++   V    A   V GYT A D+G  D+    + S L + K  D F P+GP +V + 
Sbjct: 116 VGRRMKGVGMEEALSCVAGYTCANDVGLHDFRHADRGSMLRV-KGQDGFLPLGPEVVPAS 174

Query: 195 EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGV 254
              +P++  ++  +NG   Q+      +  +   +A L  ++TL PGD++LTGTP     
Sbjct: 175 RF-DPEDFALRTYLNGEVVQEGGAEDLLFGVAYQLADLCRLITLEPGDVVLTGTPAN--- 230

Query: 255 YRNPPEFLQPGDVITSEIENIGTFETRVEEF 285
              P   ++PGDV+  EIE IG     VEE+
Sbjct: 231 -SRP---MRPGDVVEVEIEGIGRLSNTVEEW 257


>UniRef50_A0JY14 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Arthrobacter|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Arthrobacter sp. (strain FB24)
          Length = 277

 Score =  103 bits (248), Expect = 4e-21
 Identities = 65/187 (34%), Positives = 101/187 (54%), Gaps = 13/187 (6%)

Query: 98  PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 157
           P  F+K  ++VVGP D I+L   V   V  E ELT+VIG+KA  +   +A   VLG+TI 
Sbjct: 102 PQAFHKAATSVVGPGDAIELAPGVGH-VDPEAELTIVIGRKARGLTLENARGAVLGFTIG 160

Query: 158 QDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSN 217
            D+ A + +K+ ++   +  K+ DTF P GPWIVT  +      L++    NG + + ++
Sbjct: 161 NDVTARELQKSDEL--WISAKSQDTFTPAGPWIVTGLDTA---ALSIGIVHNGSELRAAS 215

Query: 218 TNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGT 277
           +     K+ +I+  L++ MTL PGD++LTG P            L PGD +T  ++ IG 
Sbjct: 216 SADLGWKVDEILVYLTSFMTLHPGDLVLTGFPA-------ESARLHPGDTVTCRVQGIGE 268

Query: 278 FETRVEE 284
               V +
Sbjct: 269 LTNPVSD 275


>UniRef50_Q9YG48 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Aeropyrum pernix|Rep: Fumarylacetoacetate
           hydrolase family protein - Aeropyrum pernix
          Length = 286

 Score =  103 bits (248), Expect = 4e-21
 Identities = 64/204 (31%), Positives = 106/204 (51%), Gaps = 6/204 (2%)

Query: 79  VGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKK 138
           VG +Y +H  E  ++  ++ F F+K  +++ G  + + +   VS+    E E+ ++IGK+
Sbjct: 82  VGRSYAEHAREMGMSK-QIAF-FSKPVTSLTGHLNPVVVP-PVSEKPDYEGEIVIIIGKR 138

Query: 139 ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGN 198
                ++ A   + GYT   DI  TD      +S  +  K +DT+ P+GP     D   +
Sbjct: 139 IKNASTAEAGKAIAGYTAGADI--TDRLLQDMMSWSM-AKGLDTYGPVGPVATIIDSPDD 195

Query: 199 PQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNP 258
              L V   +NG + Q+  T   I  IPD+++RLS + TL PGDI+ TGTP GVG  R P
Sbjct: 196 LDGLCVHTWLNGEKVQRGCTGDMIVSIPDMVSRLSALATLRPGDIVFTGTPPGVGHARKP 255

Query: 259 PEFLQPGDVITSEIENIGTFETRV 282
           P +L+ GD +   +  +     ++
Sbjct: 256 PRYLRHGDELEVRVSGLPPLRNQI 279


>UniRef50_Q89D60 Cluster: Blr7583 protein; n=1; Bradyrhizobium
           japonicum|Rep: Blr7583 protein - Bradyrhizobium
           japonicum
          Length = 261

 Score =  103 bits (246), Expect = 7e-21
 Identities = 66/210 (31%), Positives = 98/210 (46%), Gaps = 18/210 (8%)

Query: 78  CVGLNYKDHCEE------QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIEL 131
           CVGLNY  H +E      +    P+ P I  +  + ++  ++ + +    +  +  E EL
Sbjct: 58  CVGLNYLKHLKEAADKRGEVPAVPDRPEIGYRAQNALIAHDEEVVIPSFATDKIHYEGEL 117

Query: 132 TVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIV 191
            VVIGKK   +   +A D V GYTI  D+    W+K  +   L   K  DTF P+GPWI 
Sbjct: 118 VVVIGKKVKHLTKQNAMDCVFGYTIGNDVSERSWQKADR--SLWRSKNADTFKPMGPWIE 175

Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251
           T     N   +     +NG +  +  TN  I  +   +  L+   TL PGD+I  GT G 
Sbjct: 176 TE---ANLARMETVVRVNGKETNRFYTNDMIFGVVPFLVELTKYFTLWPGDVIWMGTDGA 232

Query: 252 VGVYRNPPEFLQPGDVITSEIENIGTFETR 281
                  P+ ++ GDV+  +I  IGT   R
Sbjct: 233 ------SPD-IKHGDVVEIDITGIGTLRNR 255


>UniRef50_Q9P7L4 Cluster: Uncharacterized hydrolase C21C3.09c; n=1;
           Schizosaccharomyces pombe|Rep: Uncharacterized hydrolase
           C21C3.09c - Schizosaccharomyces pombe (Fission yeast)
          Length = 221

 Score =  103 bits (246), Expect = 7e-21
 Identities = 67/202 (33%), Positives = 107/202 (52%), Gaps = 12/202 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP-NDTIKLKMDVSKAVVCEIELTV 133
           KV+C+G NY  H  E     P  PF F K  S +V P +  + +  DVS     E+ L +
Sbjct: 7   KVVCIGRNYAAHIRELNNPFPTKPFFFLKPTSAIVEPGHGNLIIPPDVSAHYEVELGLIM 66

Query: 134 VIGKKASKVDSSHAF-DYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWI 190
                A +  SS+++ D +  Y +  D+ A + +   K   L     K  DTF P+GP I
Sbjct: 67  KDRLPARRPVSSNSWLDSIGAYFVGIDMTARNIQNEAKKKGLPWSFAKGYDTFLPVGP-I 125

Query: 191 VTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG 250
           +    I +P N+ ++ S+NG   QK +T+  ++KIP I + ++  M+L PGD++LTGTP 
Sbjct: 126 IPKHLIPDPHNVILELSLNGKVVQKDSTSLMLNKIPKIFSSITEAMSLNPGDLVLTGTPK 185

Query: 251 GVGVYRNPPEFLQPGDVITSEI 272
           GVG        + PGD++++ +
Sbjct: 186 GVGP-------VVPGDILSARL 200


>UniRef50_Q1EC44 Cluster: IP02096p; n=6; Endopterygota|Rep: IP02096p
           - Drosophila melanogaster (Fruit fly)
          Length = 236

 Score =  102 bits (245), Expect = 9e-21
 Identities = 71/211 (33%), Positives = 105/211 (49%), Gaps = 11/211 (5%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++ V LNY D    + +  P+ P +F K  S+ +     I L    +K V  E+EL VV
Sbjct: 33  KIVGVALNYMDVVLARNVPVPKEPLVFLKPTSSYLQEGQPIVLPKVFTK-VAYEVELGVV 91

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 192
           IGK    V  + A  YV GY +A D+ A       + +     LGK  DT  P+  +I  
Sbjct: 92  IGKPCKNVSKADAMSYVAGYCLALDLTAQCNLGPARAAGHPWTLGKGFDTSTPVSQFIPI 151

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252
            +++ +P NL +  ++NG  KQ   T   I K+PDII+ +S  MTL   D+ILTGTP G 
Sbjct: 152 -EKVTDPHNLPLWLTVNGDLKQNGCTADLIFKVPDIISYVSKYMTLEANDLILTGTPNGA 210

Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
             ++        GDVI   + ++     +VE
Sbjct: 211 DAFK-------AGDVIQCGMADLAKLTFQVE 234


>UniRef50_UPI00006CDD7C Cluster: fumarylacetoacetate hydrolase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           fumarylacetoacetate hydrolase family protein -
           Tetrahymena thermophila SB210
          Length = 218

 Score =  101 bits (243), Expect = 2e-20
 Identities = 68/181 (37%), Positives = 92/181 (50%), Gaps = 12/181 (6%)

Query: 73  NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELT 132
           N K+L +  NY      QK  P + P IF K  S+++   + + L       +  EIEL 
Sbjct: 13  NPKILALAQNYIP--PGQKDVPAQ-PLIFTKPHSSILYKGENLILNS--KNQINYEIELG 67

Query: 133 VVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ----LLLGKAMDTFCPIGP 188
           V+IGK    +    AFDY+ GY +  D+  TDW+  K   +      +GK  D F PI  
Sbjct: 68  VMIGKSGKNIAKQQAFDYIGGYFLCLDM--TDWDMQKANRKNGFPWDIGKGQDGFLPISD 125

Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248
           +I   D I +P N+N+K  IN   +   NT     KI DII  +S  MTL PGD+ILTGT
Sbjct: 126 FIEKKD-IKDPHNINLKLQINQKSEVDDNTKNMYFKIDDIIQYVSQYMTLNPGDLILTGT 184

Query: 249 P 249
           P
Sbjct: 185 P 185


>UniRef50_Q6D4M4 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=25; Enterobacteriaceae|Rep:
           Fumarylacetoacetate hydrolase family protein - Erwinia
           carotovora subsp. atroseptica (Pectobacterium
           atrosepticum)
          Length = 218

 Score =  101 bits (243), Expect = 2e-20
 Identities = 73/222 (32%), Positives = 107/222 (48%), Gaps = 15/222 (6%)

Query: 63  GITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVS 122
           G  L  PV+   KV+CVG NY +H +E     P  P +F K  + +      + +  ++ 
Sbjct: 9   GALLDFPVN---KVVCVGSNYSEHIKEMGSATPSEPVLFIKPETALCDLRQPVAIPKNLG 65

Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN-KKISQLL-LGKAM 180
            +V  E+EL V+IG    + +       + GY +A D+   D +   KK  Q     KA 
Sbjct: 66  -SVHHEVELAVLIGTPLKQANEERVARAIAGYGVALDLTLRDLQSEFKKAGQPWEKAKAF 124

Query: 181 DTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLP 240
           D  CPI  +I  + E G+PQ   +   +N   +Q+ NT   I  I  +IA +S   TL  
Sbjct: 125 DGSCPISGFIPVA-EFGDPQQTELGVKVNDEVRQQGNTRDMITSILPLIAYMSRFFTLRA 183

Query: 241 GDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           GDIILTGTP GVG        +  GD++T  + N  T  TR+
Sbjct: 184 GDIILTGTPKGVGP-------ILSGDMLTITV-NDRTLSTRI 217


>UniRef50_Q1GJL0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=8;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Silicibacter sp. (strain TM1040)
          Length = 256

 Score =  101 bits (242), Expect = 2e-20
 Identities = 65/182 (35%), Positives = 93/182 (51%), Gaps = 6/182 (3%)

Query: 75  KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133
           +V C+G NY  H  E    P  E PF F K P ++          M  S+ V  E EL V
Sbjct: 55  RVYCIGRNYAAHAVEMGHDPDREPPFFFQKTPDSLDASGRFPYPVM--SEDVHHEAELLV 112

Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK-NKKISQLL-LGKAMDTFCPIGPWIV 191
            +GK    +    A D+V GY +A D+   D +   KK  +   +GK+ +   P+ P + 
Sbjct: 113 ALGKGGENISEDAALDHVWGYGLALDMTRRDLQGIAKKAGRPWEIGKSFEHAAPVAP-LT 171

Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251
            +  IG+P    +  ++NG  +Q+ + NQ I KIP++IA LS    L  GD+ILTGTP G
Sbjct: 172 PATTIGHPDAGVMTLTVNGTPRQQGDLNQMIWKIPEMIAHLSQYYRLAAGDVILTGTPAG 231

Query: 252 VG 253
           VG
Sbjct: 232 VG 233


>UniRef50_Q1I918 Cluster: 4-hydroxyphenylacetate degradation;
           2-hydroxyhepta-2,4-diene-1,7- dioate isomerase; n=8;
           Pseudomonas|Rep: 4-hydroxyphenylacetate degradation;
           2-hydroxyhepta-2,4-diene-1,7- dioate isomerase -
           Pseudomonas entomophila (strain L48)
          Length = 224

 Score =  100 bits (240), Expect = 4e-20
 Identities = 59/184 (32%), Positives = 95/184 (51%), Gaps = 13/184 (7%)

Query: 94  PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 153
           PP  P +F K P+T       +     V K +     L VV+G+ AS+V + +A ++V G
Sbjct: 39  PPVKPVLFIKTPNTRNSHGQAVTYPAAV-KRLQPGPALGVVMGRDASRVSAENALEHVAG 97

Query: 154 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213
           YTI  +    +   +      +  K  D FCP+GP +V + ++ NP  L ++  +NG  +
Sbjct: 98  YTIVNEFSLPE---DSYYRPAVKAKCRDGFCPLGPQLVPAAQVANPDALGIRLWVNGELR 154

Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP-GGVGVYRNPPEFLQPGDVITSEI 272
           Q +NT   +  +  +IA +S  MTL  GD+++TGTP G + V         PGD +T EI
Sbjct: 155 QHNNTANCVRSVAQLIAEISEFMTLHAGDVLITGTPEGRIDVL--------PGDRVTVEI 206

Query: 273 ENIG 276
           + +G
Sbjct: 207 DGLG 210


>UniRef50_Q4P0N7 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 313

 Score =  100 bits (240), Expect = 4e-20
 Identities = 59/177 (33%), Positives = 91/177 (51%), Gaps = 5/177 (2%)

Query: 95  PELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGY 154
           P +P +F K  ST+ GP   I +   V++    E+EL VV+G+    V    A D +LGY
Sbjct: 108 PVIPILFYKPISTLSGPGRDIVIPPCVAEQADYEVELVVVLGRDIKDVSPVEAMDAILGY 167

Query: 155 TIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDE---IGNPQNLNVKCSINGV 211
           T++ D+ A    +   + Q  LGK+ D + PIGP +V++     I N  N+++   +N  
Sbjct: 168 TLSNDVSAR--TRMFAVPQWGLGKSFDGWLPIGPCLVSASNPRGITNRDNIHLTTKLNNR 225

Query: 212 QKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVI 268
             Q  NT+  + K  + +A LS   TL  G +++ GTP G G  R P   L  GD +
Sbjct: 226 IMQDGNTSDMLWKTAETLAELSKGTTLEAGSLLIMGTPPGEGFKRQPKVCLNHGDTL 282


>UniRef50_A7D0K4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep:
           Fumarylacetoacetate (FAA) hydrolase - Halorubrum
           lacusprofundi ATCC 49239
          Length = 273

 Score =  100 bits (239), Expect = 5e-20
 Identities = 68/221 (30%), Positives = 111/221 (50%), Gaps = 12/221 (5%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDV-S 122
           I+  AP+    K+  +GLNY +H  +     P+ P  F K  S + GP+  I+L  +  S
Sbjct: 61  ISFGAPLESFGKLWGIGLNYAEHAGDLDEQRPDEPASFMKPSSVLTGPSGPIRLPPESQS 120

Query: 123 KAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATD-WEKNKKISQLLLGKAMD 181
           + V  E EL VV+G+    V+ +   D V G+    D+ A D  ++N +   L   K+ D
Sbjct: 121 ERVTAEAELAVVMGRTCRNVEEAAFEDVVAGFLPVIDMTAEDVLQRNPRF--LTRSKSYD 178

Query: 182 TFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241
           TF   G  +   +E  +   L+V+  +NG  + ++     +    +I++  S+VMTL PG
Sbjct: 179 TFLVPGAALAVPEEPLDLDALSVQTEVNGEIEAENEIRNMLFPPSEIVSFHSDVMTLEPG 238

Query: 242 DIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           D+  TGTPG           ++PGD + + +E+IGT E  V
Sbjct: 239 DLFSTGTPGAA--------HIEPGDEVRAVVESIGTVEAPV 271


>UniRef50_Q81VG5 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=13; Bacillus|Rep: Fumarylacetoacetate
           hydrolase family protein - Bacillus anthracis
          Length = 318

 Score = 99.5 bits (237), Expect = 8e-20
 Identities = 81/303 (26%), Positives = 135/303 (44%), Gaps = 22/303 (7%)

Query: 1   MKLLQFSYKNSDGIRAGFLDGDNVVDIN-KEDPKLPSTLIELLKTNXXXXXXXXXXXX-- 57
           MK + F   + + +RAG+L+GD V+D+N   D KLPS++   L+                
Sbjct: 1   MKFVTFRLPSKE-MRAGWLEGDKVIDMNLASDGKLPSSMFAFLEKADEYVEVLRNIKNPE 59

Query: 58  --XXXLSGITLKAPVHGNDKVLCVGLNYKDHCEEQK------LTPP--ELPFIFNKFPST 107
                L  + L A +  N   +     ++ H +  +      + P   ++P  +      
Sbjct: 60  KGIYSLEEVQLAAAIP-NPSSIRDFYAFEQHVKTARGRRGLDVVPEWYDIPVFYFTNHRA 118

Query: 108 VVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK 167
           V+GPND + +    S+ +  E+E+  VIGK+   +    A +Y+ GY I  D  A D + 
Sbjct: 119 VIGPNDVV-IGPKKSEKIDYELEIACVIGKEGRNISREQAEEYIFGYCIMNDWSARDLQA 177

Query: 168 NKKISQLLLGKAMDTFCPIGPWIVTSDEI-----GNPQNLNVKCSINGVQKQKSNTNQFI 222
            +    L   K  D    +G  +VT +E+     G+   L +   +NG    K N     
Sbjct: 178 TEMKVGLGPAKGKDFATSLGAHLVTKEELDVYRNGDRYELEMTAHVNGKLLSKGNFQDIY 237

Query: 223 HKIPDIIARLSNVMTLLPGDIILTGTPG-GVGVYRNPPEFLQPGDVITSEIENIGTFETR 281
           +   ++I R S  +TL PGD+I +GT G G  +     E+LQ GDV+   I  +GT    
Sbjct: 238 YTFAEMIERASEDVTLYPGDVIGSGTVGTGCILELGTEEWLQDGDVVELTITGLGTLRNT 297

Query: 282 VEE 284
           V++
Sbjct: 298 VKK 300


>UniRef50_Q0TZ11 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 255

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 60/197 (30%), Positives = 99/197 (50%), Gaps = 3/197 (1%)

Query: 90  QKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVV-CEIELTVVIGKKASKVDSSHAF 148
           QKLT P  P ++ K  +++  PN+ I +    ++++   E EL  V  ++   V  S A 
Sbjct: 57  QKLTIPSNPPLWTKPAASLAHPNEEIPINDFCARSLPDYEGELVFVTSEECKDVTESQAK 116

Query: 149 DYVLGYTIAQDIGATDWEKNKKIS-QLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCS 207
           DY+LGYTI  D+    ++    +S Q    KA D F PI P +++     + +   +   
Sbjct: 117 DYILGYTIGNDLTCRMFQLPGNMSGQFFFAKAFDHFAPIDPVLISPKLFESVKRNGLTLK 176

Query: 208 INGVQKQKSNT-NQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGD 266
           +NG  +QK++  N  I     I++ +S   T+  G  ++TGT  GVG +R P  FLQ GD
Sbjct: 177 VNGEVRQKADLHNDMIFSPERILSHMSQGTTIPAGTAVMTGTCEGVGAFRKPKVFLQQGD 236

Query: 267 VITSEIENIGTFETRVE 283
           V+   +   GT    ++
Sbjct: 237 VVEVSMPLAGTLRNTIK 253


>UniRef50_Q1ATV1 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Rubrobacter xylanophilus (strain DSM 9941 /
           NBRC 16129)
          Length = 349

 Score = 97.9 bits (233), Expect = 3e-19
 Identities = 58/183 (31%), Positives = 88/183 (48%), Gaps = 7/183 (3%)

Query: 98  PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 157
           P++F   P+ + GP D + L  +  +    E+E   VIG+    V    A D V GYTIA
Sbjct: 145 PYLFLGSPTALCGPYDDVVLPAEGDQHD-WELEFAAVIGRSGRHVPPERALDLVAGYTIA 203

Query: 158 QDIGATDWEKNKKISQL----LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213
            DI   D      +  +    L  K   TF P GP+IV  + +G+   L +   +NG   
Sbjct: 204 NDITTRDLVYRPDLKAIGTDWLRSKNAPTFLPTGPYIVPKEFVGDTSGLRITLRLNGETM 263

Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273
           Q  + +  I  +  +++  S+ + L PGD+ILTG+P G G Y     FL  GDV+   + 
Sbjct: 264 QDESASDMIFDVARLVSYASSRVLLRPGDLILTGSPAGNGSYWG--RFLGEGDVMEGTVT 321

Query: 274 NIG 276
            +G
Sbjct: 322 GLG 324


>UniRef50_Q9X4X0 Cluster: DitH; n=8; Proteobacteria|Rep: DitH -
           Pseudomonas abietaniphila
          Length = 336

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 59/176 (33%), Positives = 94/176 (53%), Gaps = 6/176 (3%)

Query: 102 NKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIG 161
           N+F   V+G +D   L    SKA+  E+E    IGKK   +   +A D+++G+TI  D+ 
Sbjct: 147 NRF--AVIGADDEF-LWPAFSKALDFELEFGCYIGKKGKDISRDNARDHIVGFTIFNDMS 203

Query: 162 ATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTN 219
           A D +  +    L     K  DT   +GP +VT+DE+G+P +LN+   +NG +  + NT 
Sbjct: 204 ARDAQAAEMPGMLGPAKSKDFDTANIMGPCLVTADELGDPYDLNMVARVNGEEWGRGNTR 263

Query: 220 QFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 275
               +  D+IA +S   TL PG+ + +GT G  G       +L+PGD +  E++ I
Sbjct: 264 DMRWRFEDVIAHISRSETLYPGEFLGSGTVGN-GCGLEQLRYLKPGDRVELEVDGI 318


>UniRef50_Q2I760 Cluster: PlaH; n=1; Streptomyces sp. Tu6071|Rep:
           PlaH - Streptomyces sp. Tu6071
          Length = 294

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 75/227 (33%), Positives = 106/227 (46%), Gaps = 17/227 (7%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPF---IFNKFPSTVVGPNDTIKL 117
           LS +TL  P     K+ CV LNY           P  P    +  K PST+VG    +  
Sbjct: 48  LSEVTLLPPAEPT-KIACVALNYAPQGSPTGPGRPANPAACSVVLKPPSTLVGHGAVVGH 106

Query: 118 KMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLL 175
             +  + +  E EL VVIG     V +  A + V GYT A D+ A      ++ S    +
Sbjct: 107 PGEPWE-LRHEAELAVVIGTACKGVPAERAAEVVAGYTCADDLTAYVRRAPEEPSGHPPV 165

Query: 176 LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNV 235
             K  DTF P+GPW+ T  +   P ++ + C +NG  +Q   T   +  + +I+A +S  
Sbjct: 166 WAKHFDTFTPLGPWLTTDLD---PADVPITCRVNGEVRQDGGTRGLLTPVHEIVAVVSRH 222

Query: 236 MTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           M+LLPGD+ILTGTP G G        L  GD +   +  IGT    V
Sbjct: 223 MSLLPGDVILTGTPTGSGP-------LSVGDRVEVSLAGIGTLSHTV 262


>UniRef50_Q28QQ6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Proteobacteria|Rep: Fumarylacetoacetate (FAA) hydrolase
           - Jannaschia sp. (strain CCS1)
          Length = 305

 Score = 96.7 bits (230), Expect = 6e-19
 Identities = 59/191 (30%), Positives = 95/191 (49%), Gaps = 4/191 (2%)

Query: 96  ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 155
           E P  +     + +G   T++     S  +  E+EL ++IGK+ + +    A +++ GYT
Sbjct: 115 EQPIYYKGNRMSFIGHGQTVRWPA-YSDYLDLELELAIIIGKEGADIPRETAHEHIWGYT 173

Query: 156 IAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213
           I  D+ A D +  +   QL    GK  DT   +GPWIVT+DE+ +P  LN+  S+NG + 
Sbjct: 174 ILNDVSARDAQMREMAGQLGPAKGKDFDTGNILGPWIVTADEVSHPAVLNMDVSVNGERW 233

Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273
               +         IIA +S    L PG++I +GT  G G      + L  GD++   IE
Sbjct: 234 GGGTSADMQFDFAQIIAHISASERLFPGEVIGSGTV-GTGCGLEIGKRLSDGDMMDLTIE 292

Query: 274 NIGTFETRVEE 284
            IGT    +++
Sbjct: 293 KIGTLTNTIKK 303


>UniRef50_Q89QI2 Cluster: Bll3146 protein; n=11; Proteobacteria|Rep:
           Bll3146 protein - Bradyrhizobium japonicum
          Length = 262

 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 63/201 (31%), Positives = 95/201 (47%), Gaps = 9/201 (4%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELP--FIFNKFPSTVVGPNDTIKLK 118
           LS + L AP     K++ +  N+  H    KL  PE P      K  +++  P   I+  
Sbjct: 48  LSEVELLAPC-APSKIVALWNNF--HALAAKLNQPEPPEPLYLLKATTSIAAPGAVIRRP 104

Query: 119 MDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATD-WEKNKKISQLLLG 177
                    E EL +VIG+  ++V    A  ++ GYT   DI A D    +    Q    
Sbjct: 105 SYYDGKTTYEGELGIVIGRTCARVSPGEADSFIFGYTCVNDITANDILTSDPTFPQWARA 164

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           K +D + P GP I T  +   P  L V+  +NG ++Q    +  I    ++++R+S+ MT
Sbjct: 165 KGIDDYGPFGPVIATGLD---PAKLVVRTILNGAERQNYPISDMIFSAQELVSRISHDMT 221

Query: 238 LLPGDIILTGTPGGVGVYRNP 258
           LLPGD+I  GT  GVGV + P
Sbjct: 222 LLPGDLIAVGTSVGVGVMKEP 242


>UniRef50_A0GN11 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Burkholderia phytofirmans PsJN|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Burkholderia phytofirmans PsJN
          Length = 346

 Score = 94.7 bits (225), Expect = 2e-18
 Identities = 59/181 (32%), Positives = 91/181 (50%), Gaps = 5/181 (2%)

Query: 98  PFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIA 157
           P+ F +  S +  P+  I  +    + +  E+EL +VIG++   V    A ++V    I 
Sbjct: 151 PYFFQRPNSCIAPPDGEIHAESGTEE-LDWELELGIVIGRRGRHVAREDAPNFVAACLIL 209

Query: 158 QDIG--ATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQK 215
            D+   A  + ++   +  L GK M    P GP++V +  IG    L ++ S+NG   Q 
Sbjct: 210 NDVTDRALIYRQDFPGADWLRGKGMPASMPAGPYLVPASVIGEIDALRLRLSVNGEVMQD 269

Query: 216 SNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 275
                 I  +P +I  LS+ + L PGD+I TGTP G G  R    FLQ GDVI +EI+ +
Sbjct: 270 ELAGDMILDVPRLIEYLSSRVELRPGDVIATGTPAGTGAERG--RFLQDGDVIRAEIDGL 327

Query: 276 G 276
           G
Sbjct: 328 G 328


>UniRef50_A6E756 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Pedobacter sp. BAL39|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Pedobacter sp. BAL39
          Length = 332

 Score = 94.3 bits (224), Expect = 3e-18
 Identities = 63/212 (29%), Positives = 98/212 (46%), Gaps = 24/212 (11%)

Query: 96  ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 155
           + P  +    + + GP + I+   D  + +  E+E+ +VIGKK   + ++ A DY+ GY 
Sbjct: 109 QYPIFYFTNHNAIQGPGE-IECMPDHFQKLDFELEVAIVIGKKGRNITAAEADDYIAGYM 167

Query: 156 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI------------GNPQNLN 203
           I  D+ A   +  + +  L   K  D    IGPW+VT DE+            G   NL 
Sbjct: 168 IMNDMSARTLQMEEMLLNLGPAKGKDFSTVIGPWLVTPDELEVYKTAAKSGHTGISYNLE 227

Query: 204 VKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPG--------GVGVY 255
           +KC +NG Q    N         +II R +    +LPGD+I +GT G        G G+ 
Sbjct: 228 MKCLVNGQQVSSGNMADMDWTFAEIIERCAYGADILPGDVIGSGTVGTGCFLELNGTGLL 287

Query: 256 RNP---PEFLQPGDVITSEIENIGTFETRVEE 284
             P   P++LQ GDV+  EI  +G     + +
Sbjct: 288 NEPDFKPQWLQDGDVVEMEITGLGHLSNTIRK 319


>UniRef50_A6FIA8 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Moritella sp. PE36|Rep:
           Fumarylacetoacetate hydrolase family protein - Moritella
           sp. PE36
          Length = 231

 Score = 93.5 bits (222), Expect = 6e-18
 Identities = 57/182 (31%), Positives = 93/182 (51%), Gaps = 4/182 (2%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           KV+C+G NY DH  E     PE   +F K  +++V  +  + L +D+ +    E+E+ ++
Sbjct: 30  KVVCIGRNYLDHIRELGNDVPEQALLFIKPSTSLVALDKPLPLPVDLGECHN-ELEVALL 88

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKIS--QLLLGKAMDTFCPIGPWIVT 192
           I    +K  S    + + G  +  D+   D + + K         KA D  CP+ P+I  
Sbjct: 89  IKSPITKGTSIVLSELIWGVGLGLDLTLRDLQSSLKGQGHPWERAKAFDNACPVTPFIPL 148

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252
           + E G+  NL+   S+N   +Q+  T   +  I  ++  ++   TLLPGDI+LTGTP GV
Sbjct: 149 A-EFGDVNNLDFTLSVNDQLRQQGCTANMMRSIESLLTEITACFTLLPGDIVLTGTPAGV 207

Query: 253 GV 254
           GV
Sbjct: 208 GV 209


>UniRef50_A3UWQ7 Cluster: Putative uncharacterized protein; n=1;
           Vibrio splendidus 12B01|Rep: Putative uncharacterized
           protein - Vibrio splendidus 12B01
          Length = 274

 Score = 93.5 bits (222), Expect = 6e-18
 Identities = 66/209 (31%), Positives = 98/209 (46%), Gaps = 16/209 (7%)

Query: 74  DKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133
           +KV  VG+N+  H       PP +   F K PS+++   + I++    ++ V  E EL V
Sbjct: 80  EKVFAVGMNFASHLASPADAPPPM---FLKLPSSLILTGEVIQVPPK-ARNVHFEGELVV 135

Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193
           VIG++ S+     A   + G T+  DI    W+      Q L  KA D F P+G  IV  
Sbjct: 136 VIGRELSQASEEEAEQAIFGVTVGNDITERSWQGADL--QWLRAKASDGFGPVGNTIVRG 193

Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
            +  N   + +   +NG   Q+ NT+  IHK   +++ LS   TL PGD+I  GTPG   
Sbjct: 194 IDYNN---IELTTRVNGKVVQQENTSFMIHKPRKVVSYLSYYFTLKPGDLIFMGTPGRTY 250

Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRV 282
                   L   D ++  IE +GT    V
Sbjct: 251 A-------LSDKDQVSVTIEGVGTVVNEV 272


>UniRef50_A1VKI1 Cluster: Fumarylacetoacetate (FAA) hydrolase
           precursor; n=4; Proteobacteria|Rep: Fumarylacetoacetate
           (FAA) hydrolase precursor - Polaromonas
           naphthalenivorans (strain CJ2)
          Length = 245

 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 67/226 (29%), Positives = 111/226 (49%), Gaps = 19/226 (8%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           ++G T   PV    +V C+G NY+    + +  P E+P  F K  + VV  +    L   
Sbjct: 19  VAGSTAVFPV---GRVFCIGRNYR--WSQDEAMPQEMPAWFMKPANAVVHAHGV--LPYP 71

Query: 121 VSKAVVC-EIELTVVIGKKASKVDSSHAFDY-VLGYTIAQDIGATDWEKNKKIS--QLLL 176
            +    C EIEL V IG+    +  +    + + GY    D+   D ++  K +      
Sbjct: 72  PATGDFCHEIELVVAIGRGGRDIAPAQVEPHHIWGYAAGLDLTRRDLQQQAKRAGGPWEA 131

Query: 177 GKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVM 236
            KA D   P  P +V +   G+P+   V  ++NG+++Q+++ +  +  + +++A LS  +
Sbjct: 132 AKAFDHSAPCTP-LVPAAACGHPRQGAVWLTVNGIERQRADVSGLLWPVAELVAMLSRSV 190

Query: 237 TLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           TL+PGD+I TGTP GVG        LQPGDV+   +  +G F   V
Sbjct: 191 TLMPGDLIYTGTPAGVGP-------LQPGDVVQGGVAGVGQFSMTV 229


>UniRef50_A1SFW5 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Nocardioides sp. JS614|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 280

 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 60/189 (31%), Positives = 93/189 (49%), Gaps = 7/189 (3%)

Query: 97  LPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTI 156
           LP  +   P TV+GP D I      ++ +  E+EL  VIG+    +   +A D+V GYTI
Sbjct: 91  LPAYYKGLPDTVIGPEDEIPWPA-YTQRLDHELELAAVIGRPGKDITEDNALDHVFGYTI 149

Query: 157 AQDIGATDWEKNKKISQLLLGKA--MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQ 214
             D+ A D +  +    +  GKA   D    +GP IVT+DE+ +P ++ ++  +NG +  
Sbjct: 150 WNDLSARDVQAGELPVGMGPGKAKDWDGSNVLGPCIVTADEV-DPHDIELEVRVNGERWG 208

Query: 215 KSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT-PGGVGVYRNPPEFLQPGDVITSEIE 273
            +NT    H    +I   S  + L PG+++ +GT  GG GV      +L P D +  E  
Sbjct: 209 GANTRDMHHTFESMIVYASQALMLRPGEVLGSGTATGGSGVELG--RWLAPADTVEMEAS 266

Query: 274 NIGTFETRV 282
            IG     V
Sbjct: 267 GIGVLRNVV 275


>UniRef50_P53889 Cluster: Uncharacterized hydrolase YNL168C; n=7;
           Saccharomycetales|Rep: Uncharacterized hydrolase YNL168C
           - Saccharomyces cerevisiae (Baker's yeast)
          Length = 259

 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 76/231 (32%), Positives = 113/231 (48%), Gaps = 41/231 (17%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGP------------NDTIK-LKMD- 120
           K++C+G NY  H +E   + P+ PF F K  S++V P            N T   L  D 
Sbjct: 11  KIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLSSSLVKTTRPANSTFNGLNEDG 70

Query: 121 -------VSKAVVC--EIELTVVIGKKAS---KVDSSHAFDYVLGYTIAQDIGATDW--E 166
                  + + V    EIEL +++ K  S   K+     +D + G  +A D+ A +   E
Sbjct: 71  TNPGPIFIPRGVKVHHEIELALIVSKHLSNVTKMKPEEVYDSISGVALALDLTARNVQDE 130

Query: 167 KNKKISQLLLGKAMDTFCPIGPWIVTSDEIG----NPQNL-NVKCSINGVQKQKSNTNQF 221
             KK     + K  DTF PI   IV+ ++      N Q++  VKCS+NG  +Q   TN  
Sbjct: 131 AKKKGLPWTISKGFDTFMPISA-IVSREKFSSYKSNLQDIFRVKCSVNGQLRQDGGTNLM 189

Query: 222 IHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEI 272
           +H +  I+  +S +++L PGDIILTGTP GVG        L+PGD +  E+
Sbjct: 190 LHPLHKILQHISTMISLEPGDIILTGTPAGVGE-------LKPGDRVHCEL 233


>UniRef50_A6W1E0 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Marinomonas sp. MWYL1|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Marinomonas sp. MWYL1
          Length = 235

 Score = 92.7 bits (220), Expect = 1e-17
 Identities = 64/215 (29%), Positives = 104/215 (48%), Gaps = 14/215 (6%)

Query: 75  KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVV--GPNDTIKLKMDVSKAVV-CEIE 130
           +V CVG NY +H +E    P  + PF F K  S VV  G +++  +   ++ +    E+E
Sbjct: 26  RVYCVGRNYAEHSKEMGDDPERDPPFFFAKDSSCVVPAGFSESTLITYPMATSQFEYEVE 85

Query: 131 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKN--KKISQLLLGKAMDTFCPIGP 188
           L + IGK    +    + + +LGY +  D+   D +    KK     +GK+ D   PI P
Sbjct: 86  LVIAIGKGGRNLTLQQSREAILGYAVGLDMTRRDLQSQAKKKGRPWEVGKSFDESAPISP 145

Query: 189 WIVTSDEIG-NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTG 247
            ++ +D +  N     +   +NG  KQ S+       I ++I +LS V  L PGD+I+TG
Sbjct: 146 ILLKTDLLADNVSKAEIGLKVNGDLKQISHVTNLTWSIEEVICKLSEVFELRPGDLIMTG 205

Query: 248 TPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           TP  VG        +  GD + + +E++G     V
Sbjct: 206 TPENVGA-------VVVGDEMQAWVEHLGEIRVSV 233


>UniRef50_Q1ATV3 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=3;
           Actinobacteria (class)|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Rubrobacter xylanophilus (strain DSM 9941 /
           NBRC 16129)
          Length = 320

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 60/201 (29%), Positives = 96/201 (47%), Gaps = 13/201 (6%)

Query: 96  ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYT 155
           E+P  +   P +V+GP D + +     +A+  E+E+  +IG+  S +    A  ++ GYT
Sbjct: 98  EIPTFYFGNPYSVIGPQDPVAVPPGC-EALDFELEVAAIIGRAGSNLAPEEARGHIAGYT 156

Query: 156 IAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEI-----GNPQNLNVKCSING 210
           I  D  A D ++++    L   K  D    +GPWIVTSDE+         +L ++  +NG
Sbjct: 157 ILNDWSARDLQRHEMQIGLGPAKGKDFANTLGPWIVTSDELEPYRRDGRLHLEMEVFVNG 216

Query: 211 VQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG-------VGVYRNPPEFLQ 263
            +              +++A  S    + PGD++ +GT G          V R  P  L+
Sbjct: 217 EKLGDDTLANMAWSFEELVAYASRGTWVRPGDVLGSGTCGSGCLAELWGRVGRQEPPLLE 276

Query: 264 PGDVITSEIENIGTFETRVEE 284
           PGDV+   +E IGT E RV E
Sbjct: 277 PGDVVRMTVEGIGTIENRVVE 297


>UniRef50_A5VE51 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Sphingomonas wittichii RW1|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Sphingomonas wittichii RW1
          Length = 276

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 60/209 (28%), Positives = 95/209 (45%), Gaps = 15/209 (7%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K + +G+NY+   E   +  PE P ++ + P+ ++G  D I L  D    VVCE EL  V
Sbjct: 76  KYVGIGINYRATAEALGMAMPEEPVVYVRPPNCIIGDGDRIVLPADGD--VVCEGELAAV 133

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDI-GATDWEKNKKISQLLLGKAMDTFCPIGPWIVTS 193
           IG++   +       +V+GYT+  D+     + K+K      L K  D F P+GP I T 
Sbjct: 134 IGRRGRDIAEGDVAAHVIGYTLTNDLMDVARFHKDK--GNPSLAKGRDGFAPLGPCIATG 191

Query: 194 DEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVG 253
            ++   +   +   +NG + Q       +  +   ++ +S  MTL PGD++  G P    
Sbjct: 192 LDLATAE---LATFVNGARVQAGFARDMLFGVERCVSHISRFMTLEPGDVVALGCP---- 244

Query: 254 VYRNPPEFLQPGDVITSEIENIGTFETRV 282
                P  + PGD I      IGT    V
Sbjct: 245 ---PTPARIAPGDRIEIGCAPIGTLANEV 270


>UniRef50_Q22Y44 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=4; Oligohymenophorea|Rep: Fumarylacetoacetate
           hydrolase family protein - Tetrahymena thermophila SB210
          Length = 233

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 69/189 (36%), Positives = 95/189 (50%), Gaps = 11/189 (5%)

Query: 74  DKVLCVGLNYKDHCEEQKLTP-PELPFIFNKFPSTVVGPN--DTIKLKMDVSKAVVCEIE 130
           +K+L +G NY  H +E   +  P+ P IF K P + V PN     K++      V  EIE
Sbjct: 14  NKILAIGKNYVKHVKEMGGSEVPKEPVIFQK-PHSSVLPNIQKGQKVQFFTKNEVHHEIE 72

Query: 131 LTVVIGKKAS----KVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL--LGKAMDTFC 184
           L  ++ K+AS    +    +  DYV GY +A D+   + +   K +     L K  D F 
Sbjct: 73  LGFMMSKEASHKSFQKSGENWQDYVGGYFLALDLTDRNLQAAAKKAGFPWDLSKGQDKFL 132

Query: 185 PIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDII 244
           PI  +I   +++ +P NL +   ING   QK NT     KI D I   S  MTL PGD+ 
Sbjct: 133 PISSFI-PKEKVQDPYNLTLHLRINGKTIQKDNTGIMHFKIKDQIEYASKFMTLYPGDLF 191

Query: 245 LTGTPGGVG 253
           LTGTP GVG
Sbjct: 192 LTGTPDGVG 200


>UniRef50_Q4WX41 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=15; Ascomycota|Rep: Fumarylacetoacetate
           hydrolase family protein - Aspergillus fumigatus
           (Sartorya fumigata)
          Length = 235

 Score = 90.2 bits (214), Expect = 5e-17
 Identities = 74/227 (32%), Positives = 111/227 (48%), Gaps = 12/227 (5%)

Query: 66  LKA-PVHGNDKVLCVG-LNYKDHCEEQKLTPPELPFIFNKFPSTVVGPND-TIKLKMDVS 122
           LKA P H +      G LN     +E   T P+ PF F K PS+++ P +  + L   VS
Sbjct: 3   LKARPSHSHQNPRRNGSLNKSQLQKELNNTKPKQPFFFLKPPSSILLPREGPVLLPKGVS 62

Query: 123 KAVVCEIELTVVIGKKASKVDSSH---AFDYVLGYTIAQDIGATDW--EKNKKISQLLLG 177
             +  E+EL +V+GK    +D +    A D +  Y +A D+   +   E  KK     + 
Sbjct: 63  --LHYEVELALVMGKTVRDLDPNDEKGALDAIRSYLLAIDMTGRNVQDEAKKKGLPWSIA 120

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           K  DTF PI   I  +  I +P N  ++ S+    +Q  +T   +++IP  +A +S VMT
Sbjct: 121 KGFDTFLPISEEIPKA-RIPDPHNAFLRLSVGSQLRQADSTGLMLYRIPRQLAEISRVMT 179

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVEE 284
           L  GD++LTGTP GVG  +         +V   EIE  G  E  V++
Sbjct: 180 LEKGDLVLTGTPKGVGEVKAGDVMKASIEVDGKEIEE-GRIEVEVKD 225


>UniRef50_Q5KVH0 Cluster: Hypothetical conserved protein; n=2;
           Geobacillus|Rep: Hypothetical conserved protein -
           Geobacillus kaustophilus
          Length = 260

 Score = 89.8 bits (213), Expect = 7e-17
 Identities = 55/189 (29%), Positives = 92/189 (48%), Gaps = 11/189 (5%)

Query: 94  PPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLG 153
           PPE P ++ K  +T+      + L   V K +     L +VIG+ A++V    A D+V G
Sbjct: 75  PPEGPVLYMKPANTINAHRRPVLLPRWV-KHLQAAPALGLVIGRTAARVRREQALDFVFG 133

Query: 154 YTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213
           YTI  D+     ++++   +    +A D F P+GPWIV  +E     +L  +  +NG   
Sbjct: 134 YTIVNDLSIPHEQRHRPAVK---EQARDGFAPVGPWIVPKEEASPLSSLTARVYVNGRLV 190

Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273
           Q+++ ++F   +   +A ++  MTL PGD++    P            +  GDV+  EIE
Sbjct: 191 QRADPSRFRLPVEQWLAEVTEFMTLYPGDVLFFSWPADA-------PLVTAGDVVRIEIE 243

Query: 274 NIGTFETRV 282
            IG  E  +
Sbjct: 244 RIGVLENEI 252


>UniRef50_A6T028 Cluster: Faa-hydrolase family protein; n=7;
           Proteobacteria|Rep: Faa-hydrolase family protein -
           Janthinobacterium sp. (strain Marseille) (Minibacterium
           massiliensis)
          Length = 265

 Score = 89.4 bits (212), Expect = 9e-17
 Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 7/185 (3%)

Query: 75  KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTV--VGPNDTIKLKMD-VSKAVVCEIE 130
           ++ C+G NY  H  E    P  E PF F K    +  V P   +      ++K    EIE
Sbjct: 59  RIYCIGRNYAAHAREMGSDPTREPPFFFQKPSDAIQYVAPGKVVDHPYPTLTKNYHYEIE 118

Query: 131 LTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEK--NKKISQLLLGKAMDTFCPIGP 188
           L   I K    +   +A  +V GY +  D+   D +    K+     +GK+ D   PIGP
Sbjct: 119 LVAAINKGGKNISVENALQHVFGYAVGLDMTRRDLQAAMKKEEKPWEIGKSFDMSAPIGP 178

Query: 189 WIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGT 248
               +  IGN     +   +NG  KQ ++  Q I  + + I+ LS    L+PGDII +GT
Sbjct: 179 LHPVAS-IGNFTEGKIWLKVNGQVKQSADLKQMIWSVAEQISNLSKAFELMPGDIIYSGT 237

Query: 249 PGGVG 253
           P  VG
Sbjct: 238 PENVG 242


>UniRef50_A3PZU8 Cluster: 5-carboxymethyl-2-hydroxymuconate
           delta-isomerase; n=8; Actinomycetales|Rep:
           5-carboxymethyl-2-hydroxymuconate delta-isomerase -
           Mycobacterium sp. (strain JLS)
          Length = 529

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 61/212 (28%), Positives = 107/212 (50%), Gaps = 11/212 (5%)

Query: 64  ITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           I++   +  + KV+ V LNY+    ++   P   P  F K P+++      ++     ++
Sbjct: 36  ISVAEVIERSRKVIAVHLNYRSRAAQRGRFPGH-PSYFLKPPTSLALSGRPVERPAG-TR 93

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183
            +  E E+ +VIG++  +V   +++D V     A D+G  D     K S L   K  D F
Sbjct: 94  LLAFEGEIALVIGRRTRRVSPENSWDCVQFVCAANDLGVYDLRTVDKGSNLR-SKGGDGF 152

Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243
            PIGP ++++  I +P  L V+  +NG   Q  +T+  +     +IA LS ++TL  GD+
Sbjct: 153 TPIGPQLLSARGI-DPARLRVRTWVNGRLAQDGDTSDLLFPFTQLIADLSQLITLEAGDV 211

Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 275
           ILTGTP G  V       + PGD +  +++++
Sbjct: 212 ILTGTPAGSSV-------VAPGDTVEVQVDSV 236


>UniRef50_A0GBX8 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=2;
           Burkholderia|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Burkholderia phytofirmans PsJN
          Length = 257

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 53/196 (27%), Positives = 92/196 (46%), Gaps = 12/196 (6%)

Query: 63  GITLKAPVHG-------NDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTI 115
           G+  +APV G       ND+     L    H    K  PP+ P ++ K  +T+ G    +
Sbjct: 32  GMACRAPVRGAVYGTLLNDRAALAALGDAVHAAPYK-APPQAPVLYLKPRNTLAGHRARV 90

Query: 116 KLKMDVSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL 175
            +  D +  V     L +V+G+ A++V  + AFDY+ GYT+  D+        +   +  
Sbjct: 91  GVPDD-ALGVEVGASLGIVVGRTATRVGVAQAFDYIAGYTLVADLSVPHASVYRPSVRF- 148

Query: 176 LGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNV 235
             +A D FC +GP +V S  +  P NL ++  +       ++T   +  +  ++A +++ 
Sbjct: 149 --RARDGFCVVGPVVVASHHVATPDNLAIRVQLGSRDAFTASTASSVRNVAQLVADVTDF 206

Query: 236 MTLLPGDIILTGTPGG 251
           MTL  GD+I  G P G
Sbjct: 207 MTLSAGDVITLGVPHG 222


>UniRef50_A1KUG3 Cluster: Putative hydrolase; n=4; Neisseria|Rep:
           Putative hydrolase - Neisseria meningitidis serogroup C
           / serotype 2a (strain ATCC 700532 /FAM18)
          Length = 218

 Score = 88.6 bits (210), Expect = 2e-16
 Identities = 57/181 (31%), Positives = 89/181 (49%), Gaps = 5/181 (2%)

Query: 76  VLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVI 135
           + C+G NY  H EE K   P  P +F K   +++    TI L  + S+ V  E EL +++
Sbjct: 16  IFCIGRNYAAHIEELKNEIPSEPVVFMKPSGSILNSGGTILLP-EFSRDVQFECELVLLV 74

Query: 136 GKKASKV-DSSHAFDYVLGYTIAQDIGATDWEKNKKISQL--LLGKAMDTFCPIGPWIVT 192
           GK +  + +       V GY +  D+ A D + + K   L  L  K       +  +   
Sbjct: 75  GKDSDGMGEGEDILGCVAGYGVGLDLTARDIQCHLKAQGLPWLKAKGFRHSACVSDF-AA 133

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252
           +D IGNP+ +      NGV KQ+ +T   I+ I +I+ +L+    L  GD++ TGTP GV
Sbjct: 134 ADRIGNPEKVLFSLKQNGVLKQRGDTGLMIYPIREILHKLAADYGLGKGDLVFTGTPSGV 193

Query: 253 G 253
           G
Sbjct: 194 G 194


>UniRef50_A6G0I9 Cluster: 5-oxopent-3-ene-1,2,5-tricarboxylate
           decarboxylase; n=1; Plesiocystis pacifica SIR-1|Rep:
           5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase -
           Plesiocystis pacifica SIR-1
          Length = 287

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 64/213 (30%), Positives = 99/213 (46%), Gaps = 12/213 (5%)

Query: 68  APVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVC 127
           AP     KVL +G NY  H +E     P  P  F K PS ++     + L    ++ +  
Sbjct: 75  APPLAPTKVLAIGRNYAAHAKELGNEVPSSPLSFFKPPSCLLASGQPLSLPRGYAR-IDM 133

Query: 128 EIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIG 187
           E EL +VIG++A ++ ++ A+ +V  Y +  DI   D +++ K  Q    K  D F P+ 
Sbjct: 134 EAELVLVIGRRARQIAAADAWAHVGAYLMGNDISCRDLQRSDK--QWTRAKGFDGFGPVS 191

Query: 188 PWIVTSD--EIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIIL 245
            +   S   E+     L V+  +     Q   T+  I  +P ++  LS  MTL  GD+I 
Sbjct: 192 AFARLSPAAELPPVDALRVRGLLGDELVQDGPTSAMIFDVPTLLEHLSACMTLEVGDLIF 251

Query: 246 TGTPGGVGVYRNPPEFLQPGDVITSEIENIGTF 278
           TGTP GV         L+PG V   E++   +F
Sbjct: 252 TGTPAGVSA-------LEPGMVTRVELDGPPSF 277


>UniRef50_Q2W396 Cluster: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase;
           n=5; Alphaproteobacteria|Rep: 2-keto-4-pentenoate
           hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase -
           Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
          Length = 265

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 65/211 (30%), Positives = 94/211 (44%), Gaps = 14/211 (6%)

Query: 75  KVLCVGLNYKDHCEEQKLTPP-ELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTV 133
           +V CVG NY  H  E    P  E PF F K    +V     I      +  +  EIEL V
Sbjct: 62  RVFCVGRNYAGHAREMGGDPNREAPFYFTKPADALVPGGGDIPYPPGTAN-LHHEIELVV 120

Query: 134 VIGKKASKVDSSHAFDYVLGYTIAQDIGATDWE--KNKKISQLLLGKAMDTFCPIGPWIV 191
            + +   K     A   + GY +  D+   D +     K     LGKA +   PI P +V
Sbjct: 121 ALSRSVYKCTPDEASTAIFGYAVGLDMTRRDLQFAARDKGRPWCLGKAFEFSAPISP-LV 179

Query: 192 TSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGG 251
            +D      ++ ++  +NG  +Q  + N+ I  +P++IA LS    L  GD+I TGTP G
Sbjct: 180 RADAPKLAGSITLE--VNGQIRQSGDLNEMIWSVPEVIAHLSQYYHLGAGDLIFTGTPEG 237

Query: 252 VGVYRNPPEFLQPGDVITSEIENIGTFETRV 282
           VG        +  GDV+   IE +G  E  +
Sbjct: 238 VGP-------VVAGDVLRGAIEGVGELEVHI 261


>UniRef50_A6D592 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Vibrio shilonii AK1|Rep: Fumarylacetoacetate (FAA)
           hydrolase - Vibrio shilonii AK1
          Length = 264

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 66/220 (30%), Positives = 98/220 (44%), Gaps = 20/220 (9%)

Query: 65  TLKAPV-HGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSK 123
           TL AP+ HG+  V  VGLN++ H        PE+   F    +  V  +  +    D + 
Sbjct: 64  TLLAPITHGS--VYAVGLNFRSHAGNSGAAKPEI--FFKSIDA--VRLSGALSFP-DEAN 116

Query: 124 AVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183
            V  E EL +VIGK      + +A   V GY    D+    W+      Q    K    F
Sbjct: 117 NVHFEGELVIVIGKTCHDTSNQNALSCVFGYLAGNDLTERSWQGQDL--QWWRAKGATGF 174

Query: 184 CPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDI 243
            P+  +I T+ +IGN +   +   +NG   Q+      IH +P I++ +S  +TL PGD+
Sbjct: 175 GPVSNFITTNVDIGNQE---IVTRLNGKIMQQETLANMIHNVPTIVSYISKYITLRPGDM 231

Query: 244 ILTGTPGGVGVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           I  GTPG     R+       GD ++  IE IG     +E
Sbjct: 232 IFAGTPGRTRALRS-------GDNVSVSIEGIGQVSNTIE 264


>UniRef50_A5V6I4 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=1;
           Sphingomonas wittichii RW1|Rep: Fumarylacetoacetate
           (FAA) hydrolase - Sphingomonas wittichii RW1
          Length = 350

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 57/189 (30%), Positives = 94/189 (49%), Gaps = 6/189 (3%)

Query: 97  LPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGKKASK-VDSSHAFDYVLGYT 155
           +PFI+     ++VG ND + L   +      E EL +V+   A + +D   A +++ GYT
Sbjct: 140 MPFIWLATHGSLVGANDDVPLPQ-IGANHDWEAELCLVLAGGAPRYMDPEEAHEHIAGYT 198

Query: 156 IAQDI--GATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQK 213
           I  D+  G      + K +   + K+   F P+GP++V      +  +L +K  +NG  K
Sbjct: 199 IVNDMHTGELFSRDDIKWNADWIAKSPPGFKPVGPYVVPRQFFPDIDDLVIKLWVNGELK 258

Query: 214 QKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIE 273
           Q    N  I      +A  S  + +LPGD+++TG+P G G + N  +FL PGD +  EI 
Sbjct: 259 QDWPVNDMIFSSEHYVAYASERLKILPGDLLMTGSPPGNGAFHN--QFLVPGDTMDIEIS 316

Query: 274 NIGTFETRV 282
            +G    R+
Sbjct: 317 YLGRQRNRL 325


>UniRef50_Q5UY90 Cluster: 2-hydroxyhepta-24-diene-1,7-dioate
           isomerase; n=4; Halobacteriaceae|Rep:
           2-hydroxyhepta-24-diene-1,7-dioate isomerase -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 238

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 59/207 (28%), Positives = 93/207 (44%), Gaps = 17/207 (8%)

Query: 78  CVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVVIGK 137
           CVG NY    ++     PE P  F K P+ ++     I       +      EL  VIG+
Sbjct: 48  CVGRNYAATNDQMDYDRPEEPDFFIKPPTALLAHEQNIPYPPFTDELTYAG-ELAAVIGE 106

Query: 138 KASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTFCPIGPWIVTSDEIG 197
           +   +D +   D V GYTI  D+ A D +           KA D   P+GPWI T+ +  
Sbjct: 107 RCHDIDPADVSDAVRGYTILNDVDALDQQGRTA------RKAFDGSGPLGPWIETAVD-- 158

Query: 198 NPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGVGVYRN 257
            P ++++   IN  ++Q +NT++ +    +++A LS   T  PGD++  G+P   G    
Sbjct: 159 -PTDIDMYTDINDERRQSANTSEMLFGPHEVVAYLSKRFTFRPGDVVAFGSPANPGT--- 214

Query: 258 PPEFLQPGDVITSEIENIGTFETRVEE 284
               + P D I    + +GT    V E
Sbjct: 215 ----VAPDDTIEITYDGVGTLRNSVVE 237


>UniRef50_Q5GXD7 Cluster: Fumarylacetoacetate hydrolase; n=8;
           Xanthomonadaceae|Rep: Fumarylacetoacetate hydrolase -
           Xanthomonas oryzae pv. oryzae
          Length = 290

 Score = 87.4 bits (207), Expect = 4e-16
 Identities = 66/218 (30%), Positives = 101/218 (46%), Gaps = 23/218 (10%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPP-------ELPFIFNKFPSTVVGPNDTIKLKMDV 121
           PVH   ++ CVG N+ DH  E   + P       +  F      + VVG  D I      
Sbjct: 76  PVH---RIYCVGRNFADHAREMGASAPASKAERGQPTFFMKPADAIVVGHGDQIPYPPG- 131

Query: 122 SKAVVCEIELTVVIGKKA--SKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLL--LG 177
           +K +  E+EL V +G  A   ++    A   + GY +  D+   D +   K   L   + 
Sbjct: 132 TKELHHEVELVVALGSDAPAGELPVEQAERLIYGYGVGLDLTRRDLQAAAKAKGLPWDIA 191

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           K  D   PI   +V + E+G  + LN+   +NG  +Q+S  +Q I  +P+I+  LS +  
Sbjct: 192 KGFDHSAPISE-LVHAGEVGVLEALNLSLEVNGQVRQQSLLDQMIWNVPEILHALSKLYA 250

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 275
           L  GD+I  GTP GVG        L PGD  ++ +EN+
Sbjct: 251 LRAGDLIFMGTPAGVGP-------LLPGDQFSARLENV 281


>UniRef50_Q0VTE8 Cluster: Fumarylacetoacetate hydrolase family
           protein; n=1; Alcanivorax borkumensis SK2|Rep:
           Fumarylacetoacetate hydrolase family protein -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 233

 Score = 87.4 bits (207), Expect = 4e-16
 Identities = 65/218 (29%), Positives = 101/218 (46%), Gaps = 15/218 (6%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           + G  +  PV    KV+CVG NY DH +E     P+ P +F K  + +   ++ + L  +
Sbjct: 20  IDGSAMNMPV---GKVVCVGRNYADHAKELGNETPDAPILFMKPATALTSLHEPLVLP-E 75

Query: 121 VSKAVVCEIELTVVIGKKASKVDS-SHAFDYVLGYTIAQDIGATDWEKN--KKISQLLLG 177
               V  E+E+ V+IGK+  K     H    V  Y I  D+   + +    +K       
Sbjct: 76  GQGPVHHEVEMVVLIGKRIRKETRLDHVRFSVAAYGIGLDLTLREVQNQLKEKGHPWERA 135

Query: 178 KAMDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMT 237
           KA D   P+  +I  +  I   Q+L V   +N   KQ  +T Q +    ++++ +S   T
Sbjct: 136 KAFDGAAPVSGFI-DARGISVRQDLGVTLELNDAVKQHGHTGQMLFPTFELLSEISQTFT 194

Query: 238 LLPGDIILTGTPGGVGVYRNPPEFLQPGDVITSEIENI 275
           L PGD++ TGTP GVG        L  GD  T+ + NI
Sbjct: 195 LEPGDVVFTGTPAGVGP-------LNSGDKFTARLGNI 225


>UniRef50_A4EDA6 Cluster: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; n=1;
           Roseobacter sp. CCS2|Rep: Putative
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Roseobacter sp. CCS2
          Length = 257

 Score = 87.0 bits (206), Expect = 5e-16
 Identities = 65/192 (33%), Positives = 92/192 (47%), Gaps = 6/192 (3%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMD 120
           ++G TL  P     K + +  N+    E  KL  P+ P  F K  S++ GPN  + L  +
Sbjct: 41  MAGNTLLPPCEPG-KFIGLWNNFHAAAERNKLDIPQHPLFFLKPLSSLAGPNAQVALPPN 99

Query: 121 VSKAVVCEIELTVVIGKKASKVDSSHAFDYVLGYTIAQDIGATD-WEKNKKISQLLLGKA 179
           + + VV E EL +VIGK    +    A   +LGYT   DI A D   ++    Q    K 
Sbjct: 100 IGR-VVYEGELGIVIGKTCKNISVDAAESAILGYTCVNDITALDILFEDPSFPQWTRAKG 158

Query: 180 MDTFCPIGPWIVTSDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLL 239
            D F  IGP I T     N ++L VK  +N  ++Q    +  I     I+++LS  MTL 
Sbjct: 159 YDGFGVIGPVIQTDL---NWRDLTVKVMVNDRERQSYPASDMIMNPAQIVSQLSTDMTLE 215

Query: 240 PGDIILTGTPGG 251
           PGD+I  GT  G
Sbjct: 216 PGDVIACGTSIG 227


>UniRef50_A0UKA6 Cluster: Fumarylacetoacetate (FAA) hydrolase; n=6;
           Burkholderia|Rep: Fumarylacetoacetate (FAA) hydrolase -
           Burkholderia multivorans ATCC 17616
          Length = 426

 Score = 86.6 bits (205), Expect = 6e-16
 Identities = 57/190 (30%), Positives = 93/190 (48%), Gaps = 10/190 (5%)

Query: 69  PVHGNDKVLCVGLNYKDHCEEQKLTPPELPF--IFNKFPSTVVGPNDTIKLKMDVSKAVV 126
           PV  N + +C G NY+ H  E  + P    F  IF K PS +V  +  +     V + + 
Sbjct: 172 PVTANQQFVCQGANYRRHMIESGMDPDAKQFNMIFTKAPSCIVAADSRVVKPRHV-RFLD 230

Query: 127 CEIELTVVIGKKASK---VDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKAMDTF 183
            EIEL +V+ +  ++   V  ++  +YV G  I  D  A D +  +   Q   GK+  TF
Sbjct: 231 YEIELGLVLKRDITRHQPVTDANLHEYVAGIAIVNDYSARDVQIPQM--QFYKGKSFRTF 288

Query: 184 CPIGPWIVTSDEIGNPQ--NLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPG 241
            P+GP++   +    P+   L +  S+NG  +Q+ +T   ++   + +  LS V  L  G
Sbjct: 289 GPVGPYLCLLERHDFPKLKTLELTLSVNGTVRQQDSTANLVYGPAETLTELSGVHDLGAG 348

Query: 242 DIILTGTPGG 251
           D++ TGTP G
Sbjct: 349 DLLATGTPAG 358


>UniRef50_A0QDN9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=4; Actinomycetales|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Mycobacterium avium (strain 104)
          Length = 313

 Score = 86.2 bits (204), Expect = 8e-16
 Identities = 59/210 (28%), Positives = 105/210 (50%), Gaps = 11/210 (5%)

Query: 61  LSGITLKAPVHGNDKVLCVGLNYKDHCEEQKLTPPELPF-IFNKFPSTVVGPNDTIKLKM 119
           + G+ L +PV    +V+    N+  H ++  + P  +P   F K   ++ GP D I +K 
Sbjct: 52  VEGLNLLSPVTAPCRVVAQMTNFASHVKDAGMDPNTIPLTFFRKASGSITGPFDDI-VKP 110

Query: 120 DVSKAVVCEIELTVVIGKK---ASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLL 176
           D  + +  E+E+ +VIG++    + V  ++  DY  G  +  D+ A D +  K  +Q   
Sbjct: 111 DHVRFLDYEVEIGLVIGRELPVGAAVSEANLADYTAGAVVTNDVSARDIQLPK--TQFYE 168

Query: 177 GKAMDTFCPIGPWIVT--SDEIGNPQNLNVKCSINGVQKQKSNTN-QFIHKIPDIIARLS 233
            K+  TF P+GP +V   +DE+    +L ++  +NG  +Q    +   I+     +  L+
Sbjct: 169 SKSYPTFTPVGPALVLLDADELKRFGDLRLQLRVNGQVRQDMRVDGDMIYPPVQALQALA 228

Query: 234 NVMTLLPGDIILTGTPGGVGVYRNPPEFLQ 263
               L PGD++LTGTP G  +   PP+ +Q
Sbjct: 229 RFQRLDPGDLVLTGTPVGTAL-SAPPKPVQ 257


>UniRef50_Q1VYL9 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=16; Bacteroidetes|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Psychroflexus torquis ATCC 700755
          Length = 204

 Score = 85.8 bits (203), Expect = 1e-15
 Identities = 62/211 (29%), Positives = 97/211 (45%), Gaps = 10/211 (4%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K++C+G NY  H  E K   PE P +F K  S+V+  N+   +    +K V  E+E+ V 
Sbjct: 2   KLICIGRNYAKHISELKNEKPEHPVVFLKPDSSVLLKNNPFIIPA-FTKEVHHEVEILVK 60

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQLLLGKA--MDTFCPIGPWIVT 192
           I K    + +  A  Y     +  D  A D +   K   L   KA   D    IG   + 
Sbjct: 61  INKVGKHIQTKFAHKYYDEIGLGIDFTARDIQNQLKEQGLPWEKAKGFDGAAVIGETWLP 120

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTPGGV 252
            D   +  N++ +   N    Q  +T++ + +I ++IA +S   TL  GD+I TGTP GV
Sbjct: 121 KDRFQDLNNIDFRLEKNKTAVQSGSTSEMLWRIDELIAHVSEYFTLKIGDVIFTGTPAGV 180

Query: 253 GVYRNPPEFLQPGDVITSEIENIGTFETRVE 283
           G        ++ GD +   IE+   F  +V+
Sbjct: 181 G-------RVEEGDHLEGFIEDTSCFSIQVK 204


>UniRef50_A2U2G0 Cluster: 2-hydroxyhepta-2,4-diene-1,7-dioate
           isomerase; n=1; Polaribacter dokdonensis MED152|Rep:
           2-hydroxyhepta-2,4-diene-1,7-dioate isomerase -
           Polaribacter dokdonensis MED152
          Length = 203

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 56/177 (31%), Positives = 85/177 (48%), Gaps = 5/177 (2%)

Query: 75  KVLCVGLNYKDHCEEQKLTPPELPFIFNKFPSTVVGPNDTIKLKMDVSKAVVCEIELTVV 134
           K+L +G NY    ++         FIF+K P + +  N  +     ++  ++ E+EL V 
Sbjct: 2   KILGIGSNYVTDLKDIPEKKKGKKFIFSK-PESSLAVNCDVPYPSSITNELIYEVELVVK 60

Query: 135 IGKKASKVDSSHAFDYVLGYTIAQDIGATDWEKNKKISQ--LLLGKAMDTFCPIGPWIVT 192
           IGK+   +    A  Y+    I  D  A D   N + ++      K  D   PI  +   
Sbjct: 61  IGKEGKNITKEEANSYISEIAIGIDYTAKDILTNARETKHPWEFAKGFDGAAPISSFKPI 120

Query: 193 SDEIGNPQNLNVKCSINGVQKQKSNTNQFIHKIPDIIARLSNVMTLLPGDIILTGTP 249
           +D   +  N++    ING +KQKSNT   I+   DII+ +S  MTL PGD+I TGTP
Sbjct: 121 TDY--DLANIDFDLKINGEEKQKSNTAYMINNFADIISFISEYMTLQPGDLIFTGTP 175


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.317    0.138    0.405 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 319,996,435
Number of Sequences: 1657284
Number of extensions: 12974200
Number of successful extensions: 28902
Number of sequences better than 10.0: 336
Number of HSP's better than 10.0 without gapping: 313
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 27901
Number of HSP's gapped (non-prelim): 371
length of query: 285
length of database: 575,637,011
effective HSP length: 100
effective length of query: 185
effective length of database: 409,908,611
effective search space: 75833093035
effective search space used: 75833093035
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 72 (33.1 bits)

- SilkBase 1999-2023 -