BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001048-TA|BGIBMGA001048-PA|IPR000033|Low-density lipoprotein receptor, YWTD repeat, IPR006209|EGF-like, IPR002172|Low density lipoprotein-receptor, class A, IPR000152|Aspartic acid and asparagine hydroxylation site, IPR006210|EGF (1195 letters) Database: nematostella 59,808 sequences; 16,821,457 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SB_47667| Best HMM Match : Ldl_recept_a (HMM E-Value=0) 383 e-106 SB_51898| Best HMM Match : No HMM Matches (HMM E-Value=.) 377 e-104 SB_17350| Best HMM Match : No HMM Matches (HMM E-Value=.) 281 2e-75 SB_4238| Best HMM Match : No HMM Matches (HMM E-Value=.) 232 1e-60 SB_16934| Best HMM Match : Ldl_recept_b (HMM E-Value=1.7e-39) 184 5e-46 SB_44751| Best HMM Match : No HMM Matches (HMM E-Value=.) 130 5e-30 SB_45709| Best HMM Match : No HMM Matches (HMM E-Value=.) 129 1e-29 SB_23513| Best HMM Match : No HMM Matches (HMM E-Value=.) 126 1e-28 SB_26126| Best HMM Match : Ldl_recept_b (HMM E-Value=3e-24) 107 4e-23 SB_47029| Best HMM Match : Ldl_recept_b (HMM E-Value=8.2e-28) 100 1e-20 SB_47789| Best HMM Match : Ldl_recept_a (HMM E-Value=4.2e-34) 97 1e-19 SB_18560| Best HMM Match : No HMM Matches (HMM E-Value=.) 88 3e-17 SB_35244| Best HMM Match : Ldl_recept_b (HMM E-Value=3.2e-11) 67 7e-11 SB_35533| Best HMM Match : Ldl_recept_b (HMM E-Value=9.8e-05) 64 6e-10 SB_51058| Best HMM Match : EGF (HMM E-Value=0.11) 62 3e-09 SB_40455| Best HMM Match : Ldl_recept_b (HMM E-Value=0.019) 58 6e-08 SB_5725| Best HMM Match : Ldl_recept_b (HMM E-Value=0.019) 58 6e-08 SB_20981| Best HMM Match : Ldl_recept_b (HMM E-Value=0.037) 56 1e-07 SB_40871| Best HMM Match : No HMM Matches (HMM E-Value=.) 53 1e-06 SB_54289| Best HMM Match : EGF (HMM E-Value=9.2e-05) 53 1e-06 SB_41134| Best HMM Match : EGF_CA (HMM E-Value=0) 53 2e-06 SB_29649| Best HMM Match : Sushi (HMM E-Value=4.1e-18) 53 2e-06 SB_23898| Best HMM Match : Ldl_recept_a (HMM E-Value=1.4013e-45) 52 3e-06 SB_3317| Best HMM Match : EGF (HMM E-Value=1e-06) 51 6e-06 SB_12366| Best HMM Match : SRCR (HMM E-Value=4.4e-33) 51 6e-06 SB_37830| Best HMM Match : Peptidase_C54 (HMM E-Value=3.3e-11) 50 9e-06 SB_59093| Best HMM Match : Ldl_recept_b (HMM E-Value=8.1e-06) 50 1e-05 SB_53569| Best HMM Match : EGF_CA (HMM E-Value=0) 48 5e-05 SB_18886| Best HMM Match : PPC (HMM E-Value=9.4) 47 8e-05 SB_13199| Best HMM Match : No HMM Matches (HMM E-Value=.) 46 1e-04 SB_55908| Best HMM Match : Sushi (HMM E-Value=1.6e-12) 46 2e-04 SB_51974| Best HMM Match : No HMM Matches (HMM E-Value=.) 46 2e-04 SB_26052| Best HMM Match : EGF (HMM E-Value=4e-06) 46 2e-04 SB_39808| Best HMM Match : EGF_CA (HMM E-Value=6.3e-35) 45 4e-04 SB_58882| Best HMM Match : EGF_CA (HMM E-Value=0) 44 6e-04 SB_13477| Best HMM Match : Ldl_recept_a (HMM E-Value=0) 44 7e-04 SB_11375| Best HMM Match : EGF_CA (HMM E-Value=0) 44 0.001 SB_35576| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.001 SB_15410| Best HMM Match : No HMM Matches (HMM E-Value=.) 44 0.001 SB_57009| Best HMM Match : Zona_pellucida (HMM E-Value=0) 43 0.001 SB_6273| Best HMM Match : MAM (HMM E-Value=0) 43 0.002 SB_26480| Best HMM Match : EGF (HMM E-Value=0) 42 0.002 SB_47055| Best HMM Match : No HMM Matches (HMM E-Value=.) 42 0.004 SB_20531| Best HMM Match : No HMM Matches (HMM E-Value=.) 42 0.004 SB_48688| Best HMM Match : Ldl_recept_a (HMM E-Value=7.8e-26) 42 0.004 SB_30577| Best HMM Match : Ldl_recept_a (HMM E-Value=2.8e-25) 42 0.004 SB_50311| Best HMM Match : Ldl_recept_a (HMM E-Value=3.4e-20) 41 0.005 SB_5000| Best HMM Match : EGF_CA (HMM E-Value=0) 41 0.005 SB_55657| Best HMM Match : EGF_CA (HMM E-Value=0) 41 0.005 SB_27746| Best HMM Match : MAM (HMM E-Value=1.4013e-45) 41 0.005 SB_51525| Best HMM Match : EGF_CA (HMM E-Value=0.001) 41 0.007 SB_43556| Best HMM Match : Ldl_recept_a (HMM E-Value=2.7e-11) 41 0.007 SB_41418| Best HMM Match : EGF_CA (HMM E-Value=0) 41 0.007 SB_38403| Best HMM Match : PP2C (HMM E-Value=8.5e-35) 40 0.009 SB_18178| Best HMM Match : No HMM Matches (HMM E-Value=.) 40 0.012 SB_8425| Best HMM Match : EGF (HMM E-Value=0) 40 0.012 SB_23022| Best HMM Match : CUB (HMM E-Value=0) 40 0.016 SB_34822| Best HMM Match : EGF_CA (HMM E-Value=8.9e-09) 40 0.016 SB_5319| Best HMM Match : Ldl_recept_a (HMM E-Value=7.56701e-44) 39 0.021 SB_21284| Best HMM Match : F5_F8_type_C (HMM E-Value=1.8e-21) 39 0.028 SB_27178| Best HMM Match : No HMM Matches (HMM E-Value=.) 39 0.028 SB_59441| Best HMM Match : Ldl_recept_b (HMM E-Value=1.4) 38 0.037 SB_50657| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.037 SB_31927| Best HMM Match : Ldl_recept_a (HMM E-Value=2.3e-27) 38 0.037 SB_21597| Best HMM Match : ig (HMM E-Value=2.9e-14) 38 0.049 SB_13504| Best HMM Match : No HMM Matches (HMM E-Value=.) 38 0.064 SB_58993| Best HMM Match : EGF_CA (HMM E-Value=0) 37 0.085 SB_28492| Best HMM Match : EGF_CA (HMM E-Value=2.2e-15) 37 0.085 SB_18810| Best HMM Match : No HMM Matches (HMM E-Value=.) 37 0.085 SB_56441| Best HMM Match : No HMM Matches (HMM E-Value=.) 37 0.085 SB_43823| Best HMM Match : MAM (HMM E-Value=0) 37 0.085 SB_42336| Best HMM Match : Sushi (HMM E-Value=1.5e-08) 37 0.11 SB_29580| Best HMM Match : Ldl_recept_a (HMM E-Value=4.2e-38) 37 0.11 SB_33423| Best HMM Match : Ldl_recept_a (HMM E-Value=7.8e-22) 36 0.15 SB_31087| Best HMM Match : Ldl_recept_a (HMM E-Value=4.2e-32) 36 0.20 SB_51630| Best HMM Match : Fz (HMM E-Value=3.3e-34) 36 0.26 SB_47980| Best HMM Match : EGF_CA (HMM E-Value=7.6e-20) 36 0.26 SB_13200| Best HMM Match : No HMM Matches (HMM E-Value=.) 36 0.26 SB_56451| Best HMM Match : EGF (HMM E-Value=0.053) 35 0.34 SB_45647| Best HMM Match : HSP70 (HMM E-Value=0) 35 0.34 SB_35350| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 0.34 SB_16935| Best HMM Match : Cadherin (HMM E-Value=0) 35 0.34 SB_21487| Best HMM Match : MAM (HMM E-Value=0) 35 0.45 SB_19121| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 0.45 SB_46360| Best HMM Match : EGF (HMM E-Value=0) 34 0.79 SB_6077| Best HMM Match : EGF (HMM E-Value=0) 34 0.79 SB_43077| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 1.0 SB_26647| Best HMM Match : EGF_CA (HMM E-Value=1.1e-05) 33 1.0 SB_2014| Best HMM Match : MAM (HMM E-Value=0) 33 1.0 SB_20014| Best HMM Match : EGF_CA (HMM E-Value=1.6e-18) 33 1.0 SB_24529| Best HMM Match : Lectin_C (HMM E-Value=3.4e-27) 33 1.4 SB_58994| Best HMM Match : EGF_CA (HMM E-Value=2.3e-29) 33 1.8 SB_4874| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 1.8 SB_33986| Best HMM Match : EGF_CA (HMM E-Value=3.5e-17) 33 1.8 SB_32491| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 1.8 SB_24583| Best HMM Match : EGF (HMM E-Value=0.74) 33 1.8 SB_48293| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 3.2 SB_47409| Best HMM Match : Ldl_recept_a (HMM E-Value=1.2e-17) 32 3.2 SB_38935| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 3.2 SB_54100| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 3.2 SB_44255| Best HMM Match : RVT_1 (HMM E-Value=7.6e-29) 32 3.2 SB_22727| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 3.2 SB_8478| Best HMM Match : No HMM Matches (HMM E-Value=.) 32 3.2 SB_59402| Best HMM Match : DUF1690 (HMM E-Value=3.4) 31 4.2 SB_32816| Best HMM Match : EGF_CA (HMM E-Value=3.1e-11) 31 4.2 SB_28600| Best HMM Match : EGF_CA (HMM E-Value=4.2e-40) 31 4.2 SB_23501| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 4.2 SB_19614| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 4.2 SB_18415| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 4.2 SB_55149| Best HMM Match : Ldl_recept_a (HMM E-Value=2.6e-23) 31 4.2 SB_55021| Best HMM Match : EGF_CA (HMM E-Value=1.4013e-45) 31 4.2 SB_48962| Best HMM Match : Cadherin (HMM E-Value=0) 31 5.6 SB_48794| Best HMM Match : Transposase_5 (HMM E-Value=2.3) 31 5.6 SB_46333| Best HMM Match : EGF (HMM E-Value=1.10001e-40) 31 5.6 SB_23032| Best HMM Match : RVT_1 (HMM E-Value=1.1e-23) 31 5.6 SB_17635| Best HMM Match : CUB (HMM E-Value=0) 31 5.6 SB_58157| Best HMM Match : RVT_1 (HMM E-Value=1.6e-36) 31 5.6 SB_57293| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 5.6 SB_37757| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 7.4 SB_28272| Best HMM Match : EGF (HMM E-Value=2.6e-15) 31 7.4 SB_37171| Best HMM Match : EGF (HMM E-Value=2.6e-15) 31 7.4 SB_34310| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 7.4 SB_28040| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 7.4 SB_20131| Best HMM Match : RVT_1 (HMM E-Value=0.0049) 31 7.4 SB_17897| Best HMM Match : Ldl_recept_a (HMM E-Value=1.2e-14) 31 7.4 SB_40813| Best HMM Match : No HMM Matches (HMM E-Value=.) 30 9.8 SB_39600| Best HMM Match : Sushi (HMM E-Value=0) 30 9.8 SB_32754| Best HMM Match : No HMM Matches (HMM E-Value=.) 30 9.8 SB_21158| Best HMM Match : Chromo (HMM E-Value=0.00035) 30 9.8 SB_10498| Best HMM Match : Ldl_recept_a (HMM E-Value=2.7e-07) 30 9.8 >SB_47667| Best HMM Match : Ldl_recept_a (HMM E-Value=0) Length = 3891 Score = 383 bits (943), Expect = e-106 Identities = 225/699 (32%), Positives = 354/699 (50%), Gaps = 31/699 (4%) Query: 246 YDESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQML 305 YDE + D CKK N CS C+ +P G C C G + ++ TC + Sbjct: 157 YDEGSHCL---DLDCKKKN--CSQRCVQTPR--GGECRCFPGYTISKDL-ITCKGPYKPW 208 Query: 306 LVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLD 365 L+ + I ++SLD T Y L +++L R ++VDFD + +YW D I + Sbjct: 209 LIFSNCKDIRQVSLDG---TQYDLLIRNLTRAISVDFDWLEKKVYWTDVRENAIYRQNYT 265 Query: 366 GSDQS-----VVVRSS-GVPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTEL 419 + S V+R+ +P +A+D + R +Y+ + + I V++LDGS +I T+L Sbjct: 266 WASSSFATHETVIRTGLAMPVGLAVDWVGRNLYFVESSVRRIYVSKLDGSMRTSLITTDL 325 Query: 420 YDPRAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKL 479 PR IA+ G++FW+DW + IERAN+DGS RV+L + W N++ LD + Sbjct: 326 SKPRGIAVDPRVGYLFWTDWEAHR--IERANMDGSSRVILAKTNVYWANTLTLDYTLQTV 383 Query: 480 YWGDARTHKIEVCNMDGTERKELHSNDIIHIFGXXXXXXXXXXXXMQKRTLDRINKNTGL 539 YW +A I + DG +R+EL IIH FG + + INK TG Sbjct: 384 YWVEAHLDYIGAMSYDGLKRRELRGKSIIHPFGIAIYRNELFFSDWVRHAIISINKFTGN 443 Query: 540 DRQPVVEQMANMMGVKAFRLGA-PLGWNPCADDNGGCSHLCFNRPDD-YICGCPLGLELT 597 +V + MG++ P NPC+ N GC LC + C C G +L Sbjct: 444 GTTKLVSNLEVPMGLQILHPSRQPAMPNPCSPSNCGCQQLCLVTVESGCTCRCQTGYQLA 503 Query: 598 ADKKTCVEPEAFLVYSRKNIIGRLSI-KNEYNDAVIPIKDLKEVSALALYVSGSKLYWSD 656 D+K+CVE + FL+Y+R+ I + + K++ +D + PI +L L K+Y++D Sbjct: 504 PDQKSCVEIDTFLLYARRTEISAVHLNKSDTSDPIPPILELGNAVGLDFDARERKIYFTD 563 Query: 657 SKTKTINRCSVNGSAVEKIVEWLGLVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRA 716 TI+R ++G E +V L +G+A+DW +N+YWTD I V+ L+GS R+ Sbjct: 564 VIRDTISRVGMDGKGQEVVVRNLRNADGIAVDWLARNLYWTDVDLHEISVAALNGSFRKV 623 Query: 717 IIWQGLKKPKSIVLDPKKGYMYWSELG-SKSIKRAAMDGSSVSVFMEQVGRV--HALAID 773 + +K P++IVL P +G M+WS+LG ++ + MDG++ V ++ G + LAID Sbjct: 624 LFSNNVKSPRAIVLHPHRGLMFWSDLGYPAKLESSYMDGTNRQVLVKGGGLTWPNGLAID 683 Query: 774 YERRAIYWAALDPPVVEFAFLNGTGRQTLADNIPMPYALALFNDSVYWGDWNTGQIQQAR 833 E +YW +E+ FLNGTGR+ L + P+ L +F +YW DW T I++A Sbjct: 684 TETDLLYWTDAKTDTIEYIFLNGTGRRVLLSGLKHPFGLDVFAGYIYWTDWVTLDIRRAS 743 Query: 834 KTDGSNRKSIRKDLDYISDLKLYHRAKSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCAC 893 S+ ++R L + +K+++ ++ GS+ C GCSHLCL P T + C C Sbjct: 744 VASPSDVTALRSQLFGLMMIKVFNSSRQQGSSACSDGTSGCSHLCLLNP----TGHVCMC 799 Query: 894 PAHYRLNK-DNITCSEPEEFLLFAQKNAVGRIMVANGEC 931 P L++ DN TC E ++ + G+ NG C Sbjct: 800 PYGMALDQLDNKTC-EKNFTVIPTPPCSAGKFTCKNGHC 837 Score = 361 bits (889), Expect = 1e-99 Identities = 203/624 (32%), Positives = 327/624 (52%), Gaps = 20/624 (3%) Query: 8 TRITTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFK----IVSEGL 63 T+ + ++L + +VDF + + + W+D + I NY T+ F ++ GL Sbjct: 225 TQYDLLIRNLTRAISVDFDWLEKKVYWTDVRENAIYRQNY--TWASSSFATHETVIRTGL 282 Query: 64 VTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFW 123 P G+A+DW LY+ + +I V + R L +++ R IAV P G +FW Sbjct: 283 AMPVGLAVDWVGRNLYFVESSVRRIYVSKLDGSMRTSLITTDLSKPRGIAVDPRVGYLFW 342 Query: 124 TDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFN 183 TDW E +IERA M+G ++R ++ + N++W N +T+DY +YWV+A L ++ + ++ Sbjct: 343 TDW-EAHRIERANMDG--SSRVILAKTNVYWANTLTLDYTLQTVYWVEAHLDYIGAMSYD 399 Query: 184 GEKRKRVVKGGLVYPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADI 243 G KR+ + +++PF + ++L+++DW +I + + G +L+ + VP + Sbjct: 400 GLKRRELRGKSIIHPFGIAIYRNELFFSDWVRHAIISIN-KFTGNGTTKLVSNLEVPMGL 458 Query: 244 KVYDESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQ 303 ++ SRQ A PC +N GC LCL++ + G C C TG +L + + C + Sbjct: 459 QILHPSRQ--PAMPNPCSPSNCGCQQLCLVTVES-GCTCRCQTGYQLAPDQKS-CVEIDT 514 Query: 304 MLLVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKAR 363 LL A+R+ IS + L+ D + P+ +L + +DFD + IY+ D + TIS+ Sbjct: 515 FLLY-ARRTEISAVHLNKSDTSDPIPPILELGNAVGLDFDARERKIYFTDVIRDTISRVG 573 Query: 364 LDGSDQSVVVRSSGVPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPR 423 +DG Q VVVR+ D IA+D L+R +YWTD + I+VA L+GS+ KV+ + PR Sbjct: 574 MDGKGQEVVVRNLRNADGIAVDWLARNLYWTDVDLHEISVAALNGSFRKVLFSNNVKSPR 633 Query: 424 AIALHLTAGWMFWSDWNEKKPKIERANLDGSGR-VLLISEKLTWPNSIALDTVNNKLYWG 482 AI LH G MFWSD K+E + +DG+ R VL+ LTWPN +A+DT + LYW Sbjct: 634 AIVLHPHRGLMFWSDLG-YPAKLESSYMDGTNRQVLVKGGGLTWPNGLAIDTETDLLYWT 692 Query: 483 DARTHKIEVCNMDGTERKELHSNDIIHIFGXXXXXXXXXXXXMQKRTLDRINKNTGLDRQ 542 DA+T IE ++GT R+ L S + H FG + R + + D Sbjct: 693 DAKTDTIEYIFLNGTGRRVLLSG-LKHPFGLDVFAGYIYWTDWVTLDIRRASVASPSDVT 751 Query: 543 PVVEQMANMMGVKAFRLGAPLGWNPCADDNGGCSHLCFNRPDDYICGCPLGLEL-TADKK 601 + Q+ +M +K F G + C+D GCSHLC P ++C CP G+ L D K Sbjct: 752 ALRSQLFGLMMIKVFNSSRQQGSSACSDGTSGCSHLCLLNPTGHVCMCPYGMALDQLDNK 811 Query: 602 TCVEPEAFLVYSRKNIIGRLSIKN 625 TC E ++ + G+ + KN Sbjct: 812 TC-EKNFTVIPTPPCSAGKFTCKN 834 Score = 227 bits (556), Expect = 3e-59 Identities = 145/531 (27%), Positives = 255/531 (48%), Gaps = 26/531 (4%) Query: 575 CSHLCFNRPDDYICGCPLGLELTADKKTCVEP-EAFLVYSRKNIIGRLSIKNEYNDAVIP 633 CS C P C C G ++ D TC P + +L++S I ++S+ D +I Sbjct: 173 CSQRCVQTPRGGECRCFPGYTISKDLITCKGPYKPWLIFSNCKDIRQVSLDGTQYDLLI- 231 Query: 634 IKDLKEVSALALYVSGSKLYWSDSKTKTINR-----CSVNGSAVEKIVEW-LGLVEGLAI 687 ++L ++ K+YW+D + I R S + + E ++ L + GLA+ Sbjct: 232 -RNLTRAISVDFDWLEKKVYWTDVRENAIYRQNYTWASSSFATHETVIRTGLAMPVGLAV 290 Query: 688 DWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELGSKSI 747 DW G+N+Y+ +++ +RI VS+LDGS R ++I L KP+ I +DP+ GY++W++ + I Sbjct: 291 DWVGRNLYFVESSVRRIYVSKLDGSMRTSLITTDLSKPRGIAVDPRVGYLFWTDWEAHRI 350 Query: 748 KRAAMDGSS-VSVFMEQVGRVHALAIDYERRAIYWAALDPPVVEFAFLNGTGRQTL-ADN 805 +RA MDGSS V + V + L +DY + +YW + +G R+ L + Sbjct: 351 ERANMDGSSRVILAKTNVYWANTLTLDYTLQTVYWVEAHLDYIGAMSYDGLKRRELRGKS 410 Query: 806 IPMPYALALFNDSVYWGDWNTGQIQQARKTDGSNRKSIRKDLDYISDLKLYHRAKSMGS- 864 I P+ +A++ + +++ DW I K G+ + +L+ L++ H ++ Sbjct: 411 IIHPFGIAIYRNELFFSDWVRHAIISINKFTGNGTTKLVSNLEVPMGLQILHPSRQPAMP 470 Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFLLFAQKNAVGRI 924 N C N GC LCL T V + C C Y+L D +C E + FLL+A++ + + Sbjct: 471 NPCSPSNCGCQQLCLVT---VESGCTCRCQTGYQLAPDQKSCVEIDTFLLYARRTEISAV 527 Query: 925 MVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXX 984 + + +D P+ L N +++D E+++Y+ D +I RV + Sbjct: 528 HLNKSDTSDPIPPILELGNAVGLDFDARERKIYFTDVIRDTISRVGMDGKGQEVVVRNLR 587 Query: 985 XXXGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQT 1044 G++ +D L R +YWT D I+ ++ N S V+ + PR + H Sbjct: 588 NADGIA------VDWLARNLYWTDVDLHEISVAAL-NGSFRKVLFSNNVKSPRAIVLHPH 640 Query: 1045 KRYLIWNDVGRGAIMRAN-VDGTGRVELARADNAT---ALALDQSAGTVYW 1091 + + W+D+G A + ++ +DGT R L + T LA+D +YW Sbjct: 641 RGLMFWSDLGYPAKLESSYMDGTNRQVLVKGGGLTWPNGLAIDTETDLLYW 691 Score = 209 bits (510), Expect = 1e-53 Identities = 139/501 (27%), Positives = 227/501 (45%), Gaps = 39/501 (7%) Query: 610 LVYSRKNIIGRLSIK-NEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVN 668 LVY+ +N + +S+ NE D ++ L + +YWSD + + R +N Sbjct: 1518 LVYAARNEVRGISLDPNETTDQMVSQAGLSNAVGVTCDAQDGYVYWSDIRLDAVYRAKLN 1577 Query: 669 GSAVEKIVEW-LGLVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKS 727 GS +V+ L EG+ DW G+NIYWTD + L G + +++ + Sbjct: 1578 GSKKTSVVDSELSKPEGIVFDWIGKNIYWTDGVRHVLASHDLTGRTLCSLLHKTSANHVP 1637 Query: 728 IVLDPKKGYMYWSELGSKSIKRAAMDGSSVSVFME--QVGRVHALAIDYERRAIYWAALD 785 + P+K +R+ MDGSS V + ++G + L ID+E +YW Sbjct: 1638 SLFTPQK-------------ERSLMDGSSRRVIVHHMRMGYPNGLTIDFETNRLYWCDAS 1684 Query: 786 PPVVEFAFLNGTGRQTL--ADNIPMPYALALFNDSVYWGDWNTGQIQQARKTDGSNRKSI 843 +E A LNG R+ + + +P P+ ++L+ DS++W DW QI A KT + + Sbjct: 1685 KNTIETAKLNGKNRRVIYQGNEVPHPFGISLYEDSLFWSDWTRKQIVYAPKTGTGPIRVL 1744 Query: 844 RKDLDYISDLKLYHRAKSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDN 903 R +L + + ++ + + G+N CG NGGCS LCL T + R RC C YRL D Sbjct: 1745 RANLSVVYAVDIFSKGRQKGNNLCGWKNGGCSQLCLVTGKNTR---RCTCIIGYRLIGDG 1801 Query: 904 ITCSEPEEFLLFAQKNAVGRIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDS 963 TC FLL+ + + G+ + P+TGL +++D + +Y+ D+ + Sbjct: 1802 RTCEGINSFLLYTTAKEIRALSTTPGDTTAVHPPITGLNGASFLDFDSAGRWIYYSDERA 1861 Query: 964 HSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNS 1023 IRRV + GL RP + +D +GR ++W A D I + + Sbjct: 1862 RVIRRVHVD-----GTGVQDIIATGLRRPQGIAVDWVGRNLFWCDAITDLIEVSELVILP 1916 Query: 1024 STG----------VIVRGDRMLPRHLAFHQTKRYLIWNDVGRGAIMRANVDGTGRVELAR 1073 V+ R + PR L ++YL W + IMR+ +G+ + R Sbjct: 1917 PVFACPVPVPVPLVLSRCPVIDPRALTVDWIEKYLYWIEGNSQTIMRSTFNGSAVQTVLR 1976 Query: 1074 A--DNATALALDQSAGTVYWA 1092 + D+ +LAL VYWA Sbjct: 1977 SGMDDPRSLALLPCEKLVYWA 1997 Score = 196 bits (478), Expect = 9e-50 Identities = 198/880 (22%), Positives = 370/880 (42%), Gaps = 67/880 (7%) Query: 263 NNAGCSHLCLLSPDPPGYNCACPTGVKLR-ENSSTTCYDSPQMLLVVAQRSTISKISLDS 321 N++ CS C + ++C C G +L + DS + L + R I K+ L Sbjct: 1211 NSSSCSQRCFNTRG--SFSCKCVQGYRLEPDKRRCKAADSIRPFLYFSTRREIRKLGL-- 1266 Query: 322 PDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQSVVVRSSGVP-D 380 P YT ++ L+ T+ +DFD + + +YW+D K IS++ +G+ + ++ + + + Sbjct: 1267 PPSQSYTFAVRRLRNTIGIDFDWREKRLYWSDVYKKVISRSYFNGTGREDLITDALITAE 1326 Query: 381 SIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWN 440 +A+D + R +YW+D D I V+ L+G + +V++ ++ PR + L AG++FW+DW Sbjct: 1327 GVAVDWIGRNLYWSDMRSDRIEVSTLEGKWRRVLLSEDVESPRGLVLDSNAGYLFWTDWG 1386 Query: 441 EKKPKIERANLDGSGR-VLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTER 499 P++ER+ LDGS R V+ K+ WPN + LD ++YW DA+ I C DG+ + Sbjct: 1387 -TSPRVERSWLDGSNRFVISFGIKIVWPNGLTLDLATKRVYWIDAKLDHIVSCEYDGSSK 1445 Query: 500 KEL--HSNDIIHIFGXXXXXXXXXXXXMQKRTLDRINKNTGLDRQPVVEQMANMMGVKAF 557 + + S I H F Q + + R++K G + + ++ M + A Sbjct: 1446 RIVLSGSRQINHPFAMTLFEDYLYWTDWQNKHVLRVSKLHGENVTLLSAGVSKPMDIHAV 1505 Query: 558 R-LGAP-----LGWNPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLV 611 L P L ++ G S L N D + GL A TC + ++ Sbjct: 1506 HPLRQPRDDVILLVYAARNEVRGIS-LDPNETTDQMVS-QAGLS-NAVGVTCDAQDGYVY 1562 Query: 612 YS--RKNIIGRLSIKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNG 669 +S R + + R + +V+ +L + + G +YW+D + + G Sbjct: 1563 WSDIRLDAVYRAKLNGSKKTSVVD-SELSKPEGIVFDWIGKNIYWTDGVRHVLASHDLTG 1621 Query: 670 SAVEKIVEWLGLVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAII-WQGLKKPKSI 728 + ++ S ++ T + E S +DGSSRR I+ + P + Sbjct: 1622 RTLCSLLH----------KTSANHV--PSLFTPQKERSLMDGSSRRVIVHHMRMGYPNGL 1669 Query: 729 VLDPKKGYMYWSELGSKSIKRAAMDGSSVSVFMEQVGRVHALAIDYERRAIYWAALDPPV 788 +D + +YW + +I+ A ++G + V + H I +++W+ Sbjct: 1670 TIDFETNRLYWCDASKNTIETAKLNGKNRRVIYQGNEVPHPFGISLYEDSLFWSDWTRKQ 1729 Query: 789 VEFAFLNGTGR-QTLADNIPMPYALALFNDSVYWGD----WNTGQIQQARKTDGSNRKSI 843 + +A GTG + L N+ + YA+ +F+ G+ W G Q G N + Sbjct: 1730 IVYAPKTGTGPIRVLRANLSVVYAVDIFSKGRQKGNNLCGWKNGGCSQLCLVTGKNTRRC 1789 Query: 844 RKDLDY--ISDLKLYHRAKSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNK 901 + Y I D + S + S TPGD + P LN Sbjct: 1790 TCIIGYRLIGDGRTCEGINSFLLYTTAKEIRALS----TTPGDTTAVH----PPITGLNG 1841 Query: 902 DN-ITCSEPEEFLLFAQKNA--VGRIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYW 958 + + ++ ++ + A + R+ V D I TGL+ + I D V + L+W Sbjct: 1842 ASFLDFDSAGRWIYYSDERARVIRRVHVDGTGVQD--IIATGLRRPQGIAVDWVGRNLFW 1899 Query: 959 MD------DDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVLGRTMYWTCADRD 1012 D + S + P+ + P + +D + + +YW + Sbjct: 1900 CDAITDLIEVSELVILPPVFACPVPVPVPLVLSRCPVIDPRALTVDWIEKYLYWIEGNSQ 1959 Query: 1013 SINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGAIMRANVDGTGRVELA 1072 +I ++ N S+ ++R PR LA ++ + W G+ ++ +V +G+V Sbjct: 1960 TIMRSTF-NGSAVQTVLRSGMDDPRSLALLPCEKLVYWAQWGKRPSIK-SVWTSGKVIKT 2017 Query: 1073 RADN----ATALALDQSAGTVYWAVSRQCDGQQDCEDGRD 1108 + T L +DQ+ G ++W +++ + DG D Sbjct: 2018 VLNRNLQWPTGLTIDQAEGRIFWVDAKKDIIESSLLDGTD 2057 Score = 196 bits (477), Expect = 1e-49 Identities = 159/563 (28%), Positives = 265/563 (47%), Gaps = 40/563 (7%) Query: 304 MLLVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKAR 363 +LLV A R+ + ISLD + T + L + V D + Y+YW+D + +A+ Sbjct: 1516 ILLVYAARNEVRGISLDPNETTDQMVSQAGLSNAVGVTCDAQDGYVYWSDIRLDAVYRAK 1575 Query: 364 LDGSDQSVVVRSS-GVPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDP 422 L+GS ++ VV S P+ I D + + IYWTD V + L G ++H Sbjct: 1576 LNGSKKTSVVDSELSKPEGIVFDWIGKNIYWTDGVRHVLASHDLTGRTLCSLLH------ 1629 Query: 423 RAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISE-KLTWPNSIALDTVNNKLYW 481 + A H+ + +F P+ ER+ +DGS R +++ ++ +PN + +D N+LYW Sbjct: 1630 KTSANHVPS--LF-------TPQKERSLMDGSSRRVIVHHMRMGYPNGLTIDFETNRLYW 1680 Query: 482 GDARTHKIEVCNMDGTERKELHS-NDIIHIFGXXXXXXXXXXXXMQKRTLDRINKNTGLD 540 DA + IE ++G R+ ++ N++ H FG ++ + K TG Sbjct: 1681 CDASKNTIETAKLNGKNRRVIYQGNEVPHPFGISLYEDSLFWSDWTRKQIVYAPK-TGTG 1739 Query: 541 RQPVVE-QMANMMGVKAFRLGAPLGWNPCADDNGGCSHLCF-NRPDDYICGCPLGLELTA 598 V+ ++ + V F G G N C NGGCS LC + C C +G L Sbjct: 1740 PIRVLRANLSVVYAVDIFSKGRQKGNNLCGWKNGGCSQLCLVTGKNTRRCTCIIGYRLIG 1799 Query: 599 DKKTCVEPEAFLVYSRKNIIGRLSIKNEYNDAVIP-IKDLKEVSALALYVSGSKLYWSDS 657 D +TC +FL+Y+ I LS AV P I L S L +G +Y+SD Sbjct: 1800 DGRTCEGINSFLLYTTAKEIRALSTTPGDTTAVHPPITGLNGASFLDFDSAGRWIYYSDE 1859 Query: 658 KTKTINRCSVNGSAVEKIVEW-LGLVEGLAIDWSGQNIYWTDTTTQRIEVSRL----DGS 712 + + I R V+G+ V+ I+ L +G+A+DW G+N++W D T IEVS L Sbjct: 1860 RARVIRRVHVDGTGVQDIIATGLRRPQGIAVDWVGRNLFWCDAITDLIEVSELVILPPVF 1919 Query: 713 SRRAIIWQGLKKPKSIVLDPK-------KGYMYWSELGSKSIKRAAMDGSSV-SVFMEQV 764 + + L + V+DP+ + Y+YW E S++I R+ +GS+V +V + Sbjct: 1920 ACPVPVPVPLVLSRCPVIDPRALTVDWIEKYLYWIEGNSQTIMRSTFNGSAVQTVLRSGM 1979 Query: 765 GRVHALAIDYERRAIYWAALDP-PVVEFAFLNGTGRQTLAD-NIPMPYALAL--FNDSVY 820 +LA+ + +YWA P ++ + +G +T+ + N+ P L + ++ Sbjct: 1980 DDPRSLALLPCEKLVYWAQWGKRPSIKSVWTSGKVIKTVLNRNLQWPTGLTIDQAEGRIF 2039 Query: 821 WGDWNTGQIQQARKTDGSNRKSI 843 W D I ++ DG++RK I Sbjct: 2040 WVDAKK-DIIESSLLDGTDRKII 2061 Score = 168 bits (409), Expect = 2e-41 Identities = 128/493 (25%), Positives = 220/493 (44%), Gaps = 33/493 (6%) Query: 11 TTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIA 70 T + L +DF +R+ + WSD ++I +N T G + ++++ L+T G+A Sbjct: 1273 TFAVRRLRNTIGIDFDWREKRLYWSDVYKKVISRSYFNGT--GRE-DLITDALITAEGVA 1329 Query: 71 IDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIP 130 +DW LYW+D +++IEV ++ K+R+VL +V+ R + + G +FWTDWG P Sbjct: 1330 VDWIGRNLYWSDMRSDRIEVSTLEGKWRRVLLSEDVESPRGLVLDSNAGYLFWTDWGTSP 1389 Query: 131 KIERAGMNGDPATRKVI-VRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKR 189 ++ER+ ++G + R VI I WPNG+T+D +YW+DAKL + +++G ++ Sbjct: 1390 RVERSWLDG--SNRFVISFGIKIVWPNGLTLDLATKRVYWIDAKLDHIVSCEYDGSSKRI 1447 Query: 190 VVKGG--LVYPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIKVYD 247 V+ G + +PFA+T D LYWTDWQN + +G + L P DI Sbjct: 1448 VLSGSRQINHPFAMTLFEDYLYWTDWQNKHVLRVS-KLHGENVTLLSAGVSKPMDIHAVH 1506 Query: 248 ESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTC-YDSPQMLL 306 RQ D A + + +S DP + L TC + Sbjct: 1507 PLRQ---PRDDVILLVYAARNEVRGISLDPNETTDQMVSQAGLSNAVGVTCDAQDGYVYW 1563 Query: 307 VVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDG 366 + + + L+ T ++ +L + + FD + IYW DG+ ++ L G Sbjct: 1564 SDIRLDAVYRAKLNGSKKT--SVVDSELSKPEGIVFDWIGKNIYWTDGVRHVLASHDLTG 1621 Query: 367 SDQ-SVVVRSSGVPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVII-HTELYDPRA 424 S++ ++S P + + +DGS +VI+ H + P Sbjct: 1622 RTLCSLLHKTSANHVPSLFTPQKER-------------SLMDGSSRRVIVHHMRMGYPNG 1668 Query: 425 IALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDA 484 + + ++W D K IE A L+G R +I + P+ + + L+W D Sbjct: 1669 LTIDFETNRLYWCD--ASKNTIETAKLNGKNR-RVIYQGNEVPHPFGISLYEDSLFWSDW 1725 Query: 485 RTHKIEVCNMDGT 497 +I GT Sbjct: 1726 TRKQIVYAPKTGT 1738 Score = 157 bits (381), Expect = 5e-38 Identities = 109/412 (26%), Positives = 194/412 (47%), Gaps = 19/412 (4%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEA---FLVYSRKNIIGRLS 622 N C + + CS CFN + C C G L DK+ C ++ FL +S + I +L Sbjct: 1207 NECLNSSS-CSQRCFNTRGSFSCKCVQGYRLEPDKRRCKAADSIRPFLYFSTRREIRKLG 1265 Query: 623 IKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIV-EWLGL 681 + + ++ L+ + +LYWSD K I+R NG+ E ++ + L Sbjct: 1266 LPPSQS-YTFAVRRLRNTIGIDFDWREKRLYWSDVYKKVISRSYFNGTGREDLITDALIT 1324 Query: 682 VEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSE 741 EG+A+DW G+N+YW+D + RIEVS L+G RR ++ + ++ P+ +VLD GY++W++ Sbjct: 1325 AEGVAVDWIGRNLYWSDMRSDRIEVSTLEGKWRRVLLSEDVESPRGLVLDSNAGYLFWTD 1384 Query: 742 LG-SKSIKRAAMDGSS--VSVFMEQVGRVHALAIDYERRAIYW--AALDPPVVEFAFLNG 796 G S ++R+ +DGS+ V F ++ + L +D + +YW A LD +V + Sbjct: 1385 WGTSPRVERSWLDGSNRFVISFGIKIVWPNGLTLDLATKRVYWIDAKLD-HIVSCEYDGS 1443 Query: 797 TGRQTLADN--IPMPYALALFNDSVYWGDWNTGQIQQARKTDGSNRKSIRKDLDYISDLK 854 + R L+ + I P+A+ LF D +YW DW + + K G N + + D+ Sbjct: 1444 SKRIVLSGSRQINHPFAMTLFEDYLYWTDWQNKHVLRVSKLHGENVTLLSAGVSKPMDIH 1503 Query: 855 LYHRAKSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFLL 914 H + + + + + + T + A N +TC + ++ Sbjct: 1504 AVHPLRQPRDDVILLVYAARNEVRGISLDPNETTDQMVSQAGLS-NAVGVTCDAQDGYVY 1562 Query: 915 FA--QKNAVGRIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSH 964 ++ + +AV R + NG + + + L I +D + K +YW D H Sbjct: 1563 WSDIRLDAVYRAKL-NGSKKTSVVD-SELSKPEGIVFDWIGKNIYWTDGVRH 1612 Score = 154 bits (373), Expect = 5e-37 Identities = 122/479 (25%), Positives = 206/479 (43%), Gaps = 42/479 (8%) Query: 17 LEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIAIDWYTD 76 L V + + WSD + + + N + +K +V L P GI DW Sbjct: 1546 LSNAVGVTCDAQDGYVYWSDIRLDAVYRAKLNGS---KKTSVVDSELSKPEGIVFDWIGK 1602 Query: 77 KLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIPKIERAG 136 +YWTDG + + + + L + VP +F P+ ER+ Sbjct: 1603 NIYWTDGVRHVLASHDLTGRTLCSLLHKT-----SANHVPS---LF------TPQKERSL 1648 Query: 137 MNGDPATRKVIVRD-NIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVVKGGL 195 M+G ++R+VIV + +PNG+T+D+ + +YW DA ++ NG+ R+ + +G Sbjct: 1649 MDG--SSRRVIVHHMRMGYPNGLTIDFETNRLYWCDASKNTIETAKLNGKNRRVIYQGNE 1706 Query: 196 V-YPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIKVYDESRQIIS 254 V +PF ++ D L+W+DW I GP I+ L + V + ++ + RQ Sbjct: 1707 VPHPFGISLYEDSLFWSDWTRKQIVYAPKTGTGP-IRVLRANLSVVYAVDIFSKGRQ--- 1762 Query: 255 AEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQMLLVVAQRSTI 314 + C N GCS LCL++ C C G +L TC LL + I Sbjct: 1763 KGNNLCGWKNGGCSQLCLVT-GKNTRRCTCIIGYRL-IGDGRTCEGINSFLLYTTAKE-I 1819 Query: 315 SKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSD-QSVVV 373 +S D T P+ L +DFD +IY++D A+ I + +DG+ Q ++ Sbjct: 1820 RALSTTPGDTTAVHPPITGLNGASFLDFDSAGRWIYYSDERARVIRRVHVDGTGVQDIIA 1879 Query: 374 RSSGVPDSIAIDPLSRKIYWTDPVMDTINVARL-----------DGSYEKVIIHTELYDP 422 P IA+D + R ++W D + D I V+ L V+ + DP Sbjct: 1880 TGLRRPQGIAVDWVGRNLFWCDAITDLIEVSELVILPPVFACPVPVPVPLVLSRCPVIDP 1939 Query: 423 RAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYW 481 RA+ + +++W + N + I R+ +GS ++ + P S+AL +YW Sbjct: 1940 RALTVDWIEKYLYWIEGNSQ--TIMRSTFNGSAVQTVLRSGMDDPRSLALLPCEKLVYW 1996 Score = 147 bits (356), Expect = 5e-35 Identities = 103/363 (28%), Positives = 176/363 (48%), Gaps = 33/363 (9%) Query: 266 GCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYD-SPQML--LVVAQRSTISKISLDSP 322 GC+ C+ + C C G +L + C +P +L L+VA++ I +S+D+ Sbjct: 2572 GCNQFCINLKG--SFKCTCAKGYRLEPRNRRICKPVNPPVLAYLIVAEQGGI--VSMDTN 2627 Query: 323 DFTPYTLPLKDLKRTLTVDFDPKTEYIYWAD-GLAKTISKARLDGSDQSVVVRSSGV-PD 380 + L + + VDFD +YW G+A I +A L+GS VV+++ V P+ Sbjct: 2628 GWQRKLLV--NGSEAIAVDFDVVEGRVYWTQAGIAPQIRRAFLNGSHPEVVIQAGVVTPE 2685 Query: 381 SIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLT---------- 430 IA+D ++R +Y++D V D I V+ L G + K ++ L +PRA+ + + Sbjct: 2686 GIAVDWVARNLYFSDRVQDKIMVSTLTGRHMKTLLDN-LGEPRALVVDPSQGCQPSTYLQ 2744 Query: 431 -----AGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDAR 485 G+++++DW ++P I R LDGS ++ KL WPN + + + KL+W DA+ Sbjct: 2745 FNCTPTGFLYYTDWG-RQPHIGRVGLDGSSPQRIVESKLAWPNGLTMCRITRKLFWVDAK 2803 Query: 486 THKIEVCNMDGTERKELHSNDIIHIFGXXXXXXXXXXXXMQKRTLDRINKNTGLDRQPVV 545 +E N DGT R++L H FG ++ ++ R NK TG +R ++ Sbjct: 2804 RDVVEFANPDGTGRQQLALLHAPHPFGVTVYEDEVYWTDWRQHSISRANKWTGQNRVQLL 2863 Query: 546 EQMANMMGVKAFRLG-APLGW-NPCADDNGGCSHLCFNRPD-DYICGCPLGLELTADKKT 602 + G++ P+ NPC C+ LC P ++ C C + L D++T Sbjct: 2864 NAYYKLHGIQVVHPSQQPIPQSNPCF--KHVCTGLCLLTPQGNHRCACADNMHLANDRQT 2921 Query: 603 CVE 605 C+E Sbjct: 2922 CLE 2924 Score = 137 bits (331), Expect = 6e-32 Identities = 103/363 (28%), Positives = 175/363 (48%), Gaps = 38/363 (10%) Query: 574 GCSHLCFNRPDDYICGCPLGLELTA-DKKTC--VEPE--AFLVYSRKNIIGRLSIKNEYN 628 GC+ C N + C C G L +++ C V P A+L+ + + I + Sbjct: 2572 GCNQFCINLKGSFKCTCAKGYRLEPRNRRICKPVNPPVLAYLIVAEQGGIVSMDTNGWQR 2631 Query: 629 DAVIPIKDLKEVSALALYVSGSKLYWSDSK-TKTINRCSVNGSAVEKIVEWLGLV--EGL 685 ++ + E A+ V ++YW+ + I R +NGS E +++ G+V EG+ Sbjct: 2632 KLLV---NGSEAIAVDFDVVEGRVYWTQAGIAPQIRRAFLNGSHPEVVIQ-AGVVTPEGI 2687 Query: 686 AIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKG---------- 735 A+DW +N+Y++D +I VS L G + ++ L +P+++V+DP +G Sbjct: 2688 AVDWVARNLYFSDRVQDKIMVSTLTGRHMKTLL-DNLGEPRALVVDPSQGCQPSTYLQFN 2746 Query: 736 -----YMYWSELGSKS-IKRAAMDGSSVSVFME-QVGRVHALAIDYERRAIYWAALDPPV 788 ++Y+++ G + I R +DGSS +E ++ + L + R ++W V Sbjct: 2747 CTPTGFLYYTDWGRQPHIGRVGLDGSSPQRIVESKLAWPNGLTMCRITRKLFWVDAKRDV 2806 Query: 789 VEFAFLNGTGRQTLAD-NIPMPYALALFNDSVYWGDWNTGQIQQARKTDGSNRKSIRKDL 847 VEFA +GTGRQ LA + P P+ + ++ D VYW DW I +A K G NR + Sbjct: 2807 VEFANPDGTGRQQLALLHAPHPFGVTVYEDEVYWTDWRQHSISRANKWTGQNRVQLLNAY 2866 Query: 848 DYISDLKLYHRAKS--MGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNIT 905 + +++ H ++ SN C C+ LCL TP + ++RCAC + L D T Sbjct: 2867 YKLHGIQVVHPSQQPIPQSNPC--FKHVCTGLCLLTP---QGNHRCACADNMHLANDRQT 2921 Query: 906 CSE 908 C E Sbjct: 2922 CLE 2924 Score = 129 bits (312), Expect = 1e-29 Identities = 98/358 (27%), Positives = 158/358 (44%), Gaps = 33/358 (9%) Query: 566 NPCADDN-----GGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYSRKNIIGR 620 N C D N G CS C N + C C G LT+ L+ I + Sbjct: 3404 NKCEDVNECLHFGVCSQRCINTRGSFKCVCHEGYVLTSGSCKAAGTLPDLLVPIGGEIRQ 3463 Query: 621 LSIKNEYNDAV-IPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGS--------- 670 L + N A + D V +LA ++ +YW+DS TI R + G+ Sbjct: 3464 LQLTNSTAGAYEAAVLDQVNVGSLAYLLAEELVYWTDSYHGTIKRARLPGTLLTSSSERA 3523 Query: 671 -------AVEKIVEWLGL-VEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGL 722 A+ + +++ + V +AIDW +NIY+ D+T I V+ DG RR ++ GL Sbjct: 3524 RRDAPGPALVQTIDFPAVSVRAIAIDWVAKNIYFIDSTAHAIMVATADGRYRRTVVSSGL 3583 Query: 723 KKPKSIVLDPKKGYMYWSELGSK-SIKRAAMDGSSV-SVFMEQVGRVHALAIDYERRAIY 780 ++P I +DP G ++W++ G + + +A+DG+ S+ ++ LAID+ +Y Sbjct: 3584 EQPAGIAVDPISGRIFWTDGGYRPKVMSSALDGTDPRSLVTSELISPAGLAIDHASDVLY 3643 Query: 781 WAALDPPVVEFAFLNGTGRQTLADNIPMPYALALFNDSVYWGDWNTGQIQQARKTDGSNR 840 WA ++ L+G GR+T+ + PY+LA+ D +Y G + + K + Sbjct: 3644 WADTRTGRIDAIGLDGNGRRTVWSGLMQPYSLAVQGDWLYVSGLRNGTVYRMDKLGRGSP 3703 Query: 841 KSIRKDLDYISDLKL----YHRAKSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACP 894 + + + L + R N C + NG CSHLCL G CACP Sbjct: 3704 HVLLQGVGRAMPLAIVQSQLQRLPKRDINPCTIANGNCSHLCLSVGGRA----ICACP 3757 Score = 126 bits (303), Expect = 1e-28 Identities = 81/259 (31%), Positives = 130/259 (50%), Gaps = 24/259 (9%) Query: 58 IVSEGLVTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPE 117 ++ G+VTP GIA+DW LY++D +KI V ++ ++ K L + RA+ V P Sbjct: 2676 VIQAGVVTPEGIAVDWVARNLYFSDRVQDKIMVSTLTGRHMKTLL-DNLGEPRALVVDPS 2734 Query: 118 DG---------------LMFWTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDY 162 G +++TDWG P I R G++G R IV + WPNG+T+ Sbjct: 2735 QGCQPSTYLQFNCTPTGFLYYTDWGRQPHIGRVGLDGSSPQR--IVESKLAWPNGLTMCR 2792 Query: 163 NNSLIYWVDAKLQFVDVIDFNGEKRKRVVKGGLVYPFALTFSNDKLYWTDWQNWSIYTWD 222 ++WVDAK V+ + +G R+++ +PF +T D++YWTDW+ SI + Sbjct: 2793 ITRKLFWVDAKRDVVEFANPDGTGRQQLALLHAPHPFGVTVYEDEVYWTDWRQHSISRAN 2852 Query: 223 IAANGPKIKELIKSHPVPADIKVYDESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNC 282 G +L+ ++ I+V S+Q I + PC K+ C+ LCLL+P + C Sbjct: 2853 -KWTGQNRVQLLNAYYKLHGIQVVHPSQQPI-PQSNPCFKH--VCTGLCLLTPQ-GNHRC 2907 Query: 283 ACPTGVKLRENSSTTCYDS 301 AC + L N TC ++ Sbjct: 2908 ACADNMHL-ANDRQTCLEN 2925 Score = 116 bits (279), Expect = 1e-25 Identities = 90/348 (25%), Positives = 153/348 (43%), Gaps = 27/348 (7%) Query: 267 CSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQMLLVVAQRSTISKISLDSPDFTP 326 CS C+ + + C C G L S P +L+ + I ++ L + Sbjct: 3418 CSQRCINTRG--SFKCVCHEGYVLTSGSCKAAGTLPDLLVPIG--GEIRQLQLTNSTAGA 3473 Query: 327 YTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDG------SDQS-------VVV 373 Y + D ++ + E +YW D TI +ARL G S+++ +V Sbjct: 3474 YEAAVLDQVNVGSLAYLLAEELVYWTDSYHGTIKRARLPGTLLTSSSERARRDAPGPALV 3533 Query: 374 RSSGVPD----SIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHL 429 ++ P +IAID +++ IY+ D I VA DG Y + ++ + L P IA+ Sbjct: 3534 QTIDFPAVSVRAIAIDWVAKNIYFIDSTAHAIMVATADGRYRRTVVSSGLEQPAGIAVDP 3593 Query: 430 TAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKI 489 +G +FW+D + PK+ + LDG+ L++ +L P +A+D ++ LYW D RT +I Sbjct: 3594 ISGRIFWTDGGYR-PKVMSSALDGTDPRSLVTSELISPAGLAIDHASDVLYWADTRTGRI 3652 Query: 490 EVCNMDGTERKELHSNDIIHIFGXXXXXXXXXXXXMQKRTLDRINK----NTGLDRQPVV 545 + +DG R+ + S ++ + ++ T+ R++K + + Q V Sbjct: 3653 DAIGLDGNGRRTVWSG-LMQPYSLAVQGDWLYVSGLRNGTVYRMDKLGRGSPHVLLQGVG 3711 Query: 546 EQMANMMGVKAFRLGAPLGWNPCADDNGGCSHLCFNRPDDYICGCPLG 593 M + + NPC NG CSHLC + IC CP G Sbjct: 3712 RAMPLAIVQSQLQRLPKRDINPCTIANGNCSHLCLSVGGRAICACPDG 3759 Score = 115 bits (277), Expect = 2e-25 Identities = 70/226 (30%), Positives = 111/226 (49%), Gaps = 9/226 (3%) Query: 64 VTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFW 123 V+ IAIDW +Y+ D + I V + +YR+ + S ++ IAV P G +FW Sbjct: 3541 VSVRAIAIDWVAKNIYFIDSTAHAIMVATADGRYRRTVVSSGLEQPAGIAVDPISGRIFW 3600 Query: 124 TDWGEIPKIERAGMNG-DPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDF 182 TD G PK+ + ++G DP + +V + P G+ +D+ + ++YW D + +D I Sbjct: 3601 TDGGYRPKVMSSALDGTDP---RSLVTSELISPAGLAIDHASDVLYWADTRTGRIDAIGL 3657 Query: 183 NGEKRKRVVKGGLVYPFALTFSNDKLYWTDWQNWSIYTWDIAANG-PKIKELIKSHPVPA 241 +G R R V GL+ P++L D LY + +N ++Y D G P + +P Sbjct: 3658 DGNGR-RTVWSGLMQPYSLAVQGDWLYVSGLRNGTVYRMDKLGRGSPHVLLQGVGRAMPL 3716 Query: 242 DIKVYDESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTG 287 I V + +++ + PC N CSHLCL CACP G Sbjct: 3717 AI-VQSQLQRLPKRDINPCTIANGNCSHLCLSVGGRA--ICACPDG 3759 Score = 102 bits (244), Expect = 2e-21 Identities = 60/228 (26%), Positives = 106/228 (46%), Gaps = 8/228 (3%) Query: 63 LVTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMF 122 ++ P + +DW LYW +G + I + + + S +D R++A++P + L++ Sbjct: 1936 VIDPRALTVDWIEKYLYWIEGNSQTIMRSTFNGSAVQTVLRSGMDDPRSLALLPCEKLVY 1995 Query: 123 WTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDF 182 W WG+ P I+ +G K ++ N+ WP G+T+D I+WVDAK ++ Sbjct: 1996 WAQWGKRPSIKSVWTSGKVI--KTVLNRNLQWPTGLTIDQAEGRIFWVDAKKDIIESSLL 2053 Query: 183 NGEKRKRVVKGGLVYPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPAD 242 +G RK +V + ++ + LYWTD +I NG + + + Sbjct: 2054 DGTDRKIIVSAPGITLRSIAVFGEFLYWTDPSTSNIKRVS-KFNGGDTVQWKFATTGSSS 2112 Query: 243 IKVYDESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKL 290 ++V+ Q + PC N GC+H C + P C+CP G +L Sbjct: 2113 MRVFAREAQDCTVN--PCVL-NGGCTHTCTVLDGKP--VCSCPQGYRL 2155 Score = 99 bits (238), Expect = 1e-20 Identities = 63/220 (28%), Positives = 110/220 (50%), Gaps = 11/220 (5%) Query: 685 LAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELGS 744 L +DW + +YW + +Q I S +GS+ + ++ G+ P+S+ L P + +YW++ G Sbjct: 1942 LTVDWIEKYLYWIEGNSQTIMRSTFNGSAVQTVLRSGMDDPRSLALLPCEKLVYWAQWGK 2001 Query: 745 K-SIKRAAMDGSSV-SVFMEQVGRVHALAIDYERRAIYWAALDPPVVEFAFLNGTGRQTL 802 + SIK G + +V + L ID I+W ++E + L+GT R+ + Sbjct: 2002 RPSIKSVWTSGKVIKTVLNRNLQWPTGLTIDQAEGRIFWVDAKKDIIESSLLDGTDRKII 2061 Query: 803 --ADNIPMPYALALFNDSVYWGDWNTGQIQQARKTDGSNRKSIRKDLDYISDLKLYHR-A 859 A I + ++A+F + +YW D +T I++ K +G + + S ++++ R A Sbjct: 2062 VSAPGITL-RSIAVFGEFLYWTDPSTSNIKRVSKFNGGDTVQWKFATTGSSSMRVFAREA 2120 Query: 860 KSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRL 899 + N C V NGGC+H C G C+CP YRL Sbjct: 2121 QDCTVNPC-VLNGGCTHTCTVLDGKP----VCSCPQGYRL 2155 Score = 96.7 bits (230), Expect = 1e-19 Identities = 109/469 (23%), Positives = 190/469 (40%), Gaps = 42/469 (8%) Query: 560 GAPLGWNPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYSR----- 614 G G + C +NGGC+ LC + P+ C C G L +D KTC + L S Sbjct: 1160 GPGCGLDQCHSNNGGCAQLCMDVPEGVQCSCRPGFTLASDNKTCEDINECLNSSSCSQRC 1219 Query: 615 KNIIGRLSIKNEYNDAVIPIK-DLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGS-AV 672 N G S K + P K K ++ + LY+ S + I + + S + Sbjct: 1220 FNTRGSFSCKCVQGYRLEPDKRRCKAADSIRPF-----LYF--STRREIRKLGLPPSQSY 1272 Query: 673 EKIVEWLGLVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDP 732 V L G+ DW + +YW+D + I S +G+ R +I L + + +D Sbjct: 1273 TFAVRRLRNTIGIDFDWREKRLYWSDVYKKVISRSYFNGTGREDLITDALITAEGVAVDW 1332 Query: 733 KKGYMYWSELGSKSIKRAAMDGSSVSVFM-EQVGRVHALAIDYERRAIYWAAL-DPPVVE 790 +YWS++ S I+ + ++G V + E V L +D ++W P VE Sbjct: 1333 IGRNLYWSDMRSDRIEVSTLEGKWRRVLLSEDVESPRGLVLDSNAGYLFWTDWGTSPRVE 1392 Query: 791 FAFLNGTGRQTLADNI----PMPYALALFNDSVYWGDWNTGQIQQARKTDGSNRKSI--- 843 ++L+G+ R ++ I P L L VYW D I + DGS+++ + Sbjct: 1393 RSWLDGSNRFVISFGIKIVWPNGLTLDLATKRVYWIDAKLDHIVSC-EYDGSSKRIVLSG 1451 Query: 844 RKDLDYISDLKLY----HRAKSMGSNQCGVDNGGCSHLCLPTPGDVR-TDYRCACPAHYR 898 + +++ + L+ + + V ++ L + G + D P R Sbjct: 1452 SRQINHPFAMTLFEDYLYWTDWQNKHVLRVSKLHGENVTLLSAGVSKPMDIHAVHP--LR 1509 Query: 899 LNKDNITCSEPEEFLLFAQKNAVGRIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYW 958 +D++ L++A +N V I + E D + GL N + D + +YW Sbjct: 1510 QPRDDVI------LLVYAARNEVRGISLDPNETTDQMVSQAGLSNAVGVTCDAQDGYVYW 1563 Query: 959 MDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVLGRTMYWT 1007 D ++ R ++ LS+P +V D +G+ +YWT Sbjct: 1564 SDIRLDAVYRAKLN-----GSKKTSVVDSELSKPEGIVFDWIGKNIYWT 1607 Score = 95.1 bits (226), Expect = 3e-19 Identities = 55/219 (25%), Positives = 96/219 (43%), Gaps = 3/219 (1%) Query: 379 PDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSD 438 P ++ +D + + +YW + TI + +GS + ++ + + DPR++AL ++W+ Sbjct: 1939 PRALTVDWIEKYLYWIEGNSQTIMRSTFNGSAVQTVLRSGMDDPRSLALLPCEKLVYWAQ 1998 Query: 439 WNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTE 498 W K+P I+ G +++ L WP + +D +++W DA+ IE +DGT+ Sbjct: 1999 WG-KRPSIKSVWTSGKVIKTVLNRNLQWPTGLTIDQAEGRIFWVDAKKDIIESSLLDGTD 2057 Query: 499 RKELHSNDIIHIFGXXXXXXXXXXXXMQKRTLDRINKNTGLDRQPVVEQMANMMGVKAF- 557 RK + S I + + R++K G D ++ F Sbjct: 2058 RKIIVSAPGITLRSIAVFGEFLYWTDPSTSNIKRVSKFNGGDTVQWKFATTGSSSMRVFA 2117 Query: 558 RLGAPLGWNPCADDNGGCSHLCFNRPDDYICGCPLGLEL 596 R NPC NGGC+H C +C CP G L Sbjct: 2118 REAQDCTVNPCV-LNGGCTHTCTVLDGKPVCSCPQGYRL 2155 Score = 73.3 bits (172), Expect = 1e-12 Identities = 64/244 (26%), Positives = 109/244 (44%), Gaps = 14/244 (5%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQML--LVVAQRSTISKI 317 C NN GC+ LC+ P+ G C+C G L ++ TC D + L +QR ++ Sbjct: 1168 CHSNNGGCAQLCMDVPE--GVQCSCRPGFTLASDNK-TCEDINECLNSSSCSQRCFNTRG 1224 Query: 318 SLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQ-SVVVRSS 376 S Y L D +R D ++Y++ + I K L S + VR Sbjct: 1225 SFSCKCVQGYRLE-PDKRRCKAA--DSIRPFLYFS--TRREIRKLGLPPSQSYTFAVRRL 1279 Query: 377 GVPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFW 436 I D +++YW+D I+ + +G+ + +I L +A+ ++W Sbjct: 1280 RNTIGIDFDWREKRLYWSDVYKKVISRSYFNGTGREDLITDALITAEGVAVDWIGRNLYW 1339 Query: 437 SDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTH-KIEVCNMD 495 SD + +IE + L+G R +L+SE + P + LD+ L+W D T ++E +D Sbjct: 1340 SDM--RSDRIEVSTLEGKWRRVLLSEDVESPRGLVLDSNAGYLFWTDWGTSPRVERSWLD 1397 Query: 496 GTER 499 G+ R Sbjct: 1398 GSNR 1401 Score = 72.9 bits (171), Expect = 1e-12 Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 8/157 (5%) Query: 336 RTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQSVVVRSS-GVPDSIAIDPLSRKIYWT 394 R LTVD+ K Y+YW +G ++TI ++ +GS V+RS P S+A+ P + +YW Sbjct: 1940 RALTVDWIEK--YLYWIEGNSQTIMRSTFNGSAVQTVLRSGMDDPRSLALLPCEKLVYWA 1997 Query: 395 D-PVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKPKIERANLDG 453 +I G K +++ L P + + G +FW D KK IE + LDG Sbjct: 1998 QWGKRPSIKSVWTSGKVIKTVLNRNLQWPTGLTIDQAEGRIFWVD--AKKDIIESSLLDG 2055 Query: 454 SGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIE 490 + R +++S SIA+ LYW D T I+ Sbjct: 2056 TDRKIIVSAPGITLRSIAV--FGEFLYWTDPSTSNIK 2090 Score = 71.3 bits (167), Expect = 4e-12 Identities = 62/250 (24%), Positives = 103/250 (41%), Gaps = 22/250 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE---FLLFAQKNAV 921 N+C +++ CS C T G + C C YRL D C + FL F+ + + Sbjct: 1207 NEC-LNSSSCSQRCFNTRGS----FSCKCVQGYRLEPDKRRCKAADSIRPFLYFSTRREI 1261 Query: 922 GRIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXX 981 ++ + + + L+N I++D EK+LYW D + + IS Sbjct: 1262 RKLGLPPSQSYT--FAVRRLRNTIGIDFDWREKRLYWSD-----VYKKVISRSYFNGTGR 1314 Query: 982 XXXXXXGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAF 1041 L + +D +GR +YW+ D I ++++ V++ D PR L Sbjct: 1315 EDLITDALITAEGVAVDWIGRNLYWSDMRSDRIEVSTLEGKWRR-VLLSEDVESPRGLVL 1373 Query: 1042 HQTKRYLIWNDVGRG-AIMRANVDGTGRVELA---RADNATALALDQSAGTVYWAVSRQC 1097 YL W D G + R+ +DG+ R ++ + L LD + VYW + + Sbjct: 1374 DSNAGYLFWTDWGTSPRVERSWLDGSNRFVISFGIKIVWPNGLTLDLATKRVYW-IDAKL 1432 Query: 1098 DGQQDCE-DG 1106 D CE DG Sbjct: 1433 DHIVSCEYDG 1442 Score = 56.8 bits (131), Expect = 1e-07 Identities = 80/301 (26%), Positives = 125/301 (41%), Gaps = 31/301 (10%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEA---FLVYSRKNIIGRLSIK 624 CA +NGGCS C R IC C G EL C + F V S++ I R S K Sbjct: 3371 CAVNNGGCSQNCTERDSHVICSCWPGFELKPFTNKCEDVNECLHFGVCSQRCINTRGSFK 3430 Query: 625 NEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEWLGLVEG 684 ++ + L S A L + + + + A E V V Sbjct: 3431 CVCHEGYV----LTSGSCKAAGTLPDLLVPIGGEIRQLQLTNSTAGAYEAAVLDQVNVGS 3486 Query: 685 LAIDWSGQNIYWTDTTTQRIEVSRLDG-----SSRRA-------IIWQGLKKP----KSI 728 LA + + +YWTD+ I+ +RL G SS RA + Q + P ++I Sbjct: 3487 LAYLLAEELVYWTDSYHGTIKRARLPGTLLTSSSERARRDAPGPALVQTIDFPAVSVRAI 3546 Query: 729 VLDPKKGYMYWSELGSKSIKRAAMDGS-SVSVFMEQVGRVHALAIDYERRAIYW--AALD 785 +D +Y+ + + +I A DG +V + + +A+D I+W Sbjct: 3547 AIDWVAKNIYFIDSTAHAIMVATADGRYRRTVVSSGLEQPAGIAVDPISGRIFWTDGGYR 3606 Query: 786 PPVVEFAFLNGTG-RQTLADNIPMPYALAL--FNDSVYWGDWNTGQIQQARKTDGSNRKS 842 P V+ A L+GT R + + P LA+ +D +YW D TG+I A DG+ R++ Sbjct: 3607 PKVMSSA-LDGTDPRSLVTSELISPAGLAIDHASDVLYWADTRTGRI-DAIGLDGNGRRT 3664 Query: 843 I 843 + Sbjct: 3665 V 3665 Score = 56.4 bits (130), Expect = 1e-07 Identities = 52/210 (24%), Positives = 92/210 (43%), Gaps = 20/210 (9%) Query: 17 LEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIAIDWYTD 76 L + +DF I +SD++ +I+ ++ + T + I++ GL P GIA+DW Sbjct: 1839 LNGASFLDFDSAGRWIYYSDERARVIRRVHVDGTGVQD---IIATGLRRPQGIAVDWVGR 1895 Query: 77 KLYWTDGETNKIEVISIV-----------QKYRKVLFWSEVDLARAIAVVPEDGLMFWTD 125 L+W D T+ IEV +V VL V RA+ V + ++W + Sbjct: 1896 NLFWCDAITDLIEVSELVILPPVFACPVPVPVPLVLSRCPVIDPRALTVDWIEKYLYWIE 1955 Query: 126 WGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVD-AKLQFVDVIDFNG 184 G I R+ NG + ++R + P + + L+YW K + + +G Sbjct: 1956 -GNSQTIMRSTFNGSAV--QTVLRSGMDDPRSLALLPCEKLVYWAQWGKRPSIKSVWTSG 2012 Query: 185 EKRKRVVKGGLVYPFALTF--SNDKLYWTD 212 + K V+ L +P LT + +++W D Sbjct: 2013 KVIKTVLNRNLQWPTGLTIDQAEGRIFWVD 2042 Score = 52.8 bits (121), Expect = 2e-06 Identities = 53/242 (21%), Positives = 85/242 (35%), Gaps = 13/242 (5%) Query: 939 TGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLD 998 +G+ + R++ P EK +YW +R I L P + +D Sbjct: 1977 SGMDDPRSLALLPCEKLVYWAQWG----KRPSIKSVWTSGKVIKTVLNRNLQWPTGLTID 2032 Query: 999 VLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGAI 1058 ++W A +D I ++ +D +IV + R +A +L W D I Sbjct: 2033 QAEGRIFWVDAKKDIIESSLLDGTDRK-IIVSAPGITLRSIAVFG--EFLYWTDPSTSNI 2089 Query: 1059 MRANVDGTGRVELARADNATALALDQSAGTVYWAVSRQCDGQQDCEDGRDEAECGACGGD 1118 R + G + + AT S+ V+ ++ C +G C G Sbjct: 2090 KRVSKFNGG--DTVQWKFATT---GSSSMRVFAREAQDCTVNPCVLNGGCTHTCTVLDGK 2144 Query: 1119 VRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEGLCIAARFVCDGRPQCADGSDEAPAA 1178 C+ + F C+ G C+ FVCDG C DGSDE+ Sbjct: 2145 PVCSCPQGYRLENPYRCVLSNASCASSE-FACESGQCVRKSFVCDGDNDCHDGSDESSLV 2203 Query: 1179 CA 1180 CA Sbjct: 2204 CA 2205 Score = 52.0 bits (119), Expect = 3e-06 Identities = 32/92 (34%), Positives = 36/92 (39%), Gaps = 13/92 (14%) Query: 1096 QCDGQQDCEDGRDEAECGA--CGG-DVRCADGTXXXXX----------XXXXXXXXXXXX 1142 +CDG+ DC DG DE C C RCA G Sbjct: 3147 KCDGESDCNDGSDEKGCPPKQCAKHQYRCASGRCISASWVCDHVNDCGDGSDEQQCINRT 3206 Query: 1143 XXXDAFRCDEGLCIAARFVCDGRPQCADGSDE 1174 F CD+GLCIA + CDG CAD SDE Sbjct: 3207 CADGQFSCDDGLCIARAWKCDGMMDCADASDE 3238 Score = 48.8 bits (111), Expect = 3e-05 Identities = 47/210 (22%), Positives = 90/210 (42%), Gaps = 14/210 (6%) Query: 553 GVKAFRLGAPLGWNPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLV- 611 G+ +G L W D S L P + C P+ + L + ++P A V Sbjct: 1887 GIAVDWVGRNLFWCDAITDLIEVSELVI-LPPVFACPVPVPVPLVLSRCPVIDPRALTVD 1945 Query: 612 YSRKNII-----GRLSIKNEYNDAVIPI---KDLKEVSALALYVSGSKLYWSD-SKTKTI 662 + K + + +++ +N + + + + +LAL +YW+ K +I Sbjct: 1946 WIEKYLYWIEGNSQTIMRSTFNGSAVQTVLRSGMDDPRSLALLPCEKLVYWAQWGKRPSI 2005 Query: 663 NRCSVNGSAVEKIVEW-LGLVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQG 721 +G ++ ++ L GL ID + I+W D IE S LDG+ R+ I+ Sbjct: 2006 KSVWTSGKVIKTVLNRNLQWPTGLTIDQAEGRIFWVDAKKDIIESSLLDGTDRKIIVSAP 2065 Query: 722 LKKPKSIVLDPKKGYMYWSELGSKSIKRAA 751 +SI + + ++YW++ + +IKR + Sbjct: 2066 GITLRSIAVFGE--FLYWTDPSTSNIKRVS 2093 Score = 48.4 bits (110), Expect = 3e-05 Identities = 34/94 (36%), Positives = 37/94 (39%), Gaps = 16/94 (17%) Query: 1097 CDGQQDCEDGRDEAE---CGACGGDV---RCADGTXXXXXXXXXXXXXXXXXXXXD---- 1146 CDG+ DC DG DE+E C DV RC GT Sbjct: 2434 CDGENDCGDGSDESEEQNCERATCDVTQFRCKTGTCITREWRCDHQDDCGDGSDEQQCVN 2493 Query: 1147 ------AFRCDEGLCIAARFVCDGRPQCADGSDE 1174 F+C G CIA VCDG CADGSDE Sbjct: 2494 YTCPNHTFKCTSGHCIANSSVCDGDTDCADGSDE 2527 Score = 48.0 bits (109), Expect = 5e-05 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 7/127 (5%) Query: 943 NVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVLGR 1002 +VRAI D V K +Y++D +H+ I GL +P + +D + Sbjct: 3542 SVRAIAIDWVAKNIYFIDSTAHA-----IMVATADGRYRRTVVSSGLEQPAGIAVDPISG 3596 Query: 1003 TMYWTCAD-RDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGAIMRA 1061 ++WT R + ++++D +V + + P LA L W D G I Sbjct: 3597 RIFWTDGGYRPKVMSSALDGTDPRS-LVTSELISPAGLAIDHASDVLYWADTRTGRIDAI 3655 Query: 1062 NVDGTGR 1068 +DG GR Sbjct: 3656 GLDGNGR 3662 Score = 47.6 bits (108), Expect = 6e-05 Identities = 34/96 (35%), Positives = 40/96 (41%), Gaps = 18/96 (18%) Query: 1096 QCDGQQDCEDGRDE--AECGA---------CGGDVRC------ADGTXXXXXXXXXXXXX 1138 +CDG+ DCEDG DE A+C A C D RC DG Sbjct: 3105 RCDGESDCEDGSDENSAQCTAITCSAETFRCYSDRRCIPNQWKCDGESDCNDGSDEKGCP 3164 Query: 1139 XXXXXXXDAFRCDEGLCIAARFVCDGRPQCADGSDE 1174 +RC G CI+A +VCD C DGSDE Sbjct: 3165 PKQCAKHQ-YRCASGRCISASWVCDHVNDCGDGSDE 3199 Score = 45.6 bits (103), Expect = 2e-04 Identities = 50/245 (20%), Positives = 92/245 (37%), Gaps = 20/245 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFLLFAQKNAVGRI 924 N+C + G CS C+ T G ++C C Y L + + LL + ++ Sbjct: 3410 NEC-LHFGVCSQRCINTRGS----FKCVCHEGYVLTSGSCKAAGTLPDLLVPIGGEIRQL 3464 Query: 925 MVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXX 984 + N + NV ++ Y E+ +YW D +I+R + Sbjct: 3465 QLTNSTAGAYEAAVLDQVNVGSLAYLLAEELVYWTDSYHGTIKRARLPGTLLTSSSERAR 3524 Query: 985 XXXG-------LSRPYHMV----LDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDR 1033 + P V +D + + +Y+ + +I + D V+ G Sbjct: 3525 RDAPGPALVQTIDFPAVSVRAIAIDWVAKNIYFIDSTAHAIMVATADGRYRRTVVSSGLE 3584 Query: 1034 MLPRHLAFHQTKRYLIWNDVG-RGAIMRANVDGTGRVELARAD--NATALALDQSAGTVY 1090 P +A + W D G R +M + +DGT L ++ + LA+D ++ +Y Sbjct: 3585 Q-PAGIAVDPISGRIFWTDGGYRPKVMSSALDGTDPRSLVTSELISPAGLAIDHASDVLY 3643 Query: 1091 WAVSR 1095 WA +R Sbjct: 3644 WADTR 3648 Score = 44.8 bits (101), Expect = 4e-04 Identities = 38/157 (24%), Positives = 60/157 (38%), Gaps = 7/157 (4%) Query: 936 IPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHM 995 + + L+N I D + + LYW D D H I S + P + Sbjct: 581 VVVRNLRNADGIAVDWLARNLYWTDVDLHEI-----SVAALNGSFRKVLFSNNVKSPRAI 635 Query: 996 VLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRML-PRHLAFHQTKRYLIWNDVG 1054 VL M+W+ + +S + ++ V+V+G + P LA L W D Sbjct: 636 VLHPHRGLMFWSDLGYPAKLESSYMDGTNRQVLVKGGGLTWPNGLAIDTETDLLYWTDAK 695 Query: 1055 RGAIMRANVDGTGRVELARADNATALALDQSAGTVYW 1091 I ++GTGR + + LD AG +YW Sbjct: 696 TDTIEYIFLNGTGR-RVLLSGLKHPFGLDVFAGYIYW 731 Score = 44.8 bits (101), Expect = 4e-04 Identities = 32/108 (29%), Positives = 54/108 (50%), Gaps = 7/108 (6%) Query: 9 RITTIAKDLEQGTAVDFHYRKNLICWSD--QKPELIQCMNYNETYTGEKFKIVSEGLVTP 66 R T ++ LEQ + I W+D +P++ M+ T + + SE L++P Sbjct: 3575 RRTVVSSGLEQPAGIAVDPISGRIFWTDGGYRPKV---MSSALDGTDPRSLVTSE-LISP 3630 Query: 67 TGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAV 114 G+AID +D LYW D T +I+ I + R+ + WS + ++AV Sbjct: 3631 AGLAIDHASDVLYWADTRTGRIDAIGLDGNGRRTV-WSGLMQPYSLAV 3677 Score = 44.0 bits (99), Expect = 7e-04 Identities = 35/148 (23%), Positives = 57/148 (38%), Gaps = 7/148 (4%) Query: 945 RAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVLGRTM 1004 RA+ D +EK LYW++ +S +I R G+ P + L + + Sbjct: 1940 RALTVDWIEKYLYWIEGNSQTIMR-----STFNGSAVQTVLRSGMDDPRSLALLPCEKLV 1994 Query: 1005 YWT-CADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGAIMRANV 1063 YW R SI + V+ R + P L Q + + W D + I + + Sbjct: 1995 YWAQWGKRPSIKSVWTSGKVIKTVLNR-NLQWPTGLTIDQAEGRIFWVDAKKDIIESSLL 2053 Query: 1064 DGTGRVELARADNATALALDQSAGTVYW 1091 DGT R + A T ++ +YW Sbjct: 2054 DGTDRKIIVSAPGITLRSIAVFGEFLYW 2081 Score = 44.0 bits (99), Expect = 7e-04 Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 9/90 (10%) Query: 1093 VSRQC-DGQQDCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCD 1151 ++R C DGQ C+DG A C G + CAD + ++C Sbjct: 3203 INRTCADGQFSCDDGLCIARAWKCDGMMDCADASDEKGSGHRWCPQRL--------YQCI 3254 Query: 1152 EGLCIAARFVCDGRPQCADGSDEAPAACAY 1181 +C+ R++CD C D SDE C Y Sbjct: 3255 NHVCVDRRWLCDDMDDCGDYSDELRLLCRY 3284 Score = 43.6 bits (98), Expect = 0.001 Identities = 31/103 (30%), Positives = 38/103 (36%), Gaps = 16/103 (15%) Query: 1092 AVSRQCDGQQDCEDGRDEAECGA---CG------GDVRCA------DGTXXXXXXXXXXX 1136 +V CDG C G DE+ CG+ C + RC DG Sbjct: 2981 SVLEVCDGIPSCPAGDDESNCGSVNQCAPYHFRCDNFRCVYRSRVCDGIDDCRDGSDERN 3040 Query: 1137 XXXXXXXXXDAFRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 D FRC G CI+ ++CDG C D SDE C Sbjct: 3041 CHVTTCTA-DQFRCPSGRCISRDWLCDGDNDCGDSSDEKAGEC 3082 Score = 43.2 bits (97), Expect = 0.001 Identities = 24/73 (32%), Positives = 30/73 (41%), Gaps = 6/73 (8%) Query: 1103 CEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEGLCIAARFVC 1162 CE G+ + C GD C DG+ F C+ G CI A++VC Sbjct: 2175 CESGQCVRKSFVCDGDNDCHDGSDESSLVCASWTCEPGH------FSCNNGRCINAKWVC 2228 Query: 1163 DGRPQCADGSDEA 1175 D C D SDEA Sbjct: 2229 DRENDCGDNSDEA 2241 Score = 42.3 bits (95), Expect = 0.002 Identities = 56/242 (23%), Positives = 80/242 (33%), Gaps = 9/242 (3%) Query: 941 LKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVL 1000 +K+ RAI P ++W D + ++ SY GL+ P + +D Sbjct: 629 VKSPRAIVLHPHRGLMFWSDLGYPA--KLESSYMDGTNRQVLVKGG-GLTWPNGLAIDTE 685 Query: 1001 GRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGAIMR 1060 +YWT A D+I + N + V++ G L Y+ W D I R Sbjct: 686 TDLLYWTDAKTDTIEYIFL-NGTGRRVLLSG---LKHPFGLDVFAGYIYWTDWVTLDIRR 741 Query: 1061 ANVDGTGRVELARADNATALALDQSAGTVYWAVSRQCDGQQDCEDGRDEAECG-ACGGDV 1119 A+V V R+ + + + S DG C G C Sbjct: 742 ASVASPSDVTALRSQLFGLMMIKVFNSSRQQGSSACSDGTSGCSHLCLLNPTGHVCMCPY 801 Query: 1120 RCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEGLCIAARFVCDGRPQCADGSDEAP-AA 1178 A F C G CI+ R+ CDG C D SDE A Sbjct: 802 GMALDQLDNKTCEKNFTVIPTPPCSAGKFTCKNGHCISLRWKCDGENDCVDNSDEDEYAG 861 Query: 1179 CA 1180 CA Sbjct: 862 CA 863 Score = 42.3 bits (95), Expect = 0.002 Identities = 31/98 (31%), Positives = 36/98 (36%), Gaps = 16/98 (16%) Query: 1097 CDGQQDCEDGRDEAECG--AC-GGDVRCA------------DGTXXXXXXXXXXXXXXXX 1141 CDG+ DC D DE C C G V+C DG+ Sbjct: 2267 CDGEDDCGDFSDELRCPPTTCVPGQVKCGSKNLCIPSSWLCDGSDDCGDGWDERQDCRER 2326 Query: 1142 XXXXDAFRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 FRC G C+ A + CDG C D SDE P C Sbjct: 2327 PCNVSEFRCTSGECVPASWRCDGDNDCTDKSDE-PTDC 2363 Score = 42.3 bits (95), Expect = 0.002 Identities = 32/103 (31%), Positives = 39/103 (37%), Gaps = 18/103 (17%) Query: 1090 YWAVSR--QCDGQQDCEDGRDEAE-CGA---------CGGDVRC------ADGTXXXXXX 1131 Y +SR +CDG+ DC DG DE + C C + +C DG Sbjct: 2936 YRCISRLWRCDGEDDCGDGSDEPDSCPVRVCKPGTYQCADNRKCISVLEVCDGIPSCPAG 2995 Query: 1132 XXXXXXXXXXXXXXDAFRCDEGLCIAARFVCDGRPQCADGSDE 1174 FRCD C+ VCDG C DGSDE Sbjct: 2996 DDESNCGSVNQCAPYHFRCDNFRCVYRSRVCDGIDDCRDGSDE 3038 Score = 41.5 bits (93), Expect = 0.004 Identities = 30/95 (31%), Positives = 33/95 (34%), Gaps = 17/95 (17%) Query: 1097 CDGQQDCEDGRDEAE-------------C--GAC-GGDVRC-ADGTXXXXXXXXXXXXXX 1139 CDG DC DG DE + C G C RC D Sbjct: 2307 CDGSDDCGDGWDERQDCRERPCNVSEFRCTSGECVPASWRCDGDNDCTDKSDEPTDCQRS 2366 Query: 1140 XXXXXXDAFRCDEGLCIAARFVCDGRPQCADGSDE 1174 F CD G CI+ R +CDG C D SDE Sbjct: 2367 NATCTGAQFACDNGRCISTRLLCDGDNDCGDNSDE 2401 Score = 40.7 bits (91), Expect = 0.007 Identities = 33/105 (31%), Positives = 38/105 (36%), Gaps = 21/105 (20%) Query: 1097 CDGQQDCEDGRDE--AECGA-C-GGDVRCADG-------------TXXXXXXXXXXXXXX 1139 CDG DC D DE EC C G RCA G + Sbjct: 3065 CDGDNDCGDSSDEKAGECHVTCPAGQARCATGRRCIPSEWRCDGESDCEDGSDENSAQCT 3124 Query: 1140 XXXXXXDAFRC-DEGLCIAARFVCDGRPQCADGSDE---APAACA 1180 + FRC + CI ++ CDG C DGSDE P CA Sbjct: 3125 AITCSAETFRCYSDRRCIPNQWKCDGESDCNDGSDEKGCPPKQCA 3169 Score = 40.3 bits (90), Expect = 0.009 Identities = 30/99 (30%), Positives = 34/99 (34%), Gaps = 20/99 (20%) Query: 1096 QCDGQQDCEDGRDEAECGACG------GDVRC------------ADGTXXXXXXXXXXXX 1137 +CDG+ DC D DE E C + RC DG Sbjct: 843 KCDGENDCVDNSDEDEYAGCAEWSCRASEFRCQASRKCIPLSWRCDGDYDCLAPDLSDEA 902 Query: 1138 XXXXXXXXDA--FRCDEGLCIAARFVCDGRPQCADGSDE 1174 A FRC G C +VCDG C DGSDE Sbjct: 903 NCSVATNCSASMFRCANGQCKPRDWVCDGFDDCGDGSDE 941 Score = 39.5 bits (88), Expect = 0.016 Identities = 15/28 (53%), Positives = 19/28 (67%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEA 1175 F+C G CI ++ CDG CADGSDE+ Sbjct: 93 FQCANGRCINKKWRCDGMKDCADGSDES 120 Score = 39.5 bits (88), Expect = 0.016 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Query: 118 DGLMFWTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFV 177 +G ++WT G P+I RA +NG + +V+++ + P GI VD+ +Y+ D + Sbjct: 2649 EGRVYWTQAGIAPQIRRAFLNG--SHPEVVIQAGVVTPEGIAVDWVARNLYFSDRVQDKI 2706 Query: 178 DVIDFNGEKRKRVV 191 V G K ++ Sbjct: 2707 MVSTLTGRHMKTLL 2720 Score = 39.1 bits (87), Expect = 0.021 Identities = 33/96 (34%), Positives = 39/96 (40%), Gaps = 32/96 (33%) Query: 1097 CDGQQDCEDGRDEAECG--ACGGD-VRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEG 1153 CDG+ DC D DE +CG +CG D RC++ + RC Sbjct: 1107 CDGENDCGDRSDEVDCGLESCGNDRWRCSNTS-----------------------RC--- 1140 Query: 1154 LCIAARFVCDGRPQCADGSDEAPAACAYGHTDQVNG 1189 IA VCDGR C D SDE P C NG Sbjct: 1141 --IAKSQVCDGRVDCPDASDEGP-GCGLDQCHSNNG 1173 Score = 39.1 bits (87), Expect = 0.021 Identities = 30/104 (28%), Positives = 36/104 (34%), Gaps = 18/104 (17%) Query: 1097 CDGQQDCEDGRDEAE--CGA--CG-GDVRCADGTXXXXX----------XXXXXXXXXXX 1141 CDG DC DG DE+ C + C G C +G Sbjct: 2187 CDGDNDCHDGSDESSLVCASWTCEPGHFSCNNGRCINAKWVCDRENDCGDNSDEARCPEV 2246 Query: 1142 XXXXDAFRCDEGLCIAARFVCDGRPQCADGSDE---APAACAYG 1182 F C G C++ F+CDG C D SDE P C G Sbjct: 2247 TCPAHEFTCPNGRCVSYDFLCDGEDDCGDFSDELRCPPTTCVPG 2290 Score = 39.1 bits (87), Expect = 0.021 Identities = 17/29 (58%), Positives = 17/29 (58%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAP 1176 FRCD CI VCDG C D SDEAP Sbjct: 3292 FRCDNNKCIPKWNVCDGVYHCTDKSDEAP 3320 Score = 38.3 bits (85), Expect = 0.037 Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 2/94 (2%) Query: 1004 MYWTCADRDS-INATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGAIMRAN 1062 +Y+T R I +D SS IV P L + R L W D R + AN Sbjct: 2753 LYYTDWGRQPHIGRVGLDG-SSPQRIVESKLAWPNGLTMCRITRKLFWVDAKRDVVEFAN 2811 Query: 1063 VDGTGRVELARADNATALALDQSAGTVYWAVSRQ 1096 DGTGR +LA + VYW RQ Sbjct: 2812 PDGTGRQQLALLHAPHPFGVTVYEDEVYWTDWRQ 2845 Score = 37.9 bits (84), Expect = 0.049 Identities = 20/68 (29%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Query: 58 IVSEGLVTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPE 117 +++ L PTG+ ID +++W D + + IE + RK++ + R+IAV E Sbjct: 2018 VLNRNLQWPTGLTIDQAEGRIFWVDAKKDIIESSLLDGTDRKIIVSAPGITLRSIAVFGE 2077 Query: 118 DGLMFWTD 125 ++WTD Sbjct: 2078 --FLYWTD 2083 Score = 37.9 bits (84), Expect = 0.049 Identities = 24/81 (29%), Positives = 31/81 (38%), Gaps = 5/81 (6%) Query: 1097 CDGQQ-DCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRC-DEGL 1154 C G Q C++GR + C GD C D + + C Sbjct: 2370 CTGAQFACDNGRCISTRLLCDGDNDCGDNSDETTLQFPCVRHRNCTQSE---YSCRSTSR 2426 Query: 1155 CIAARFVCDGRPQCADGSDEA 1175 C+ FVCDG C DGSDE+ Sbjct: 2427 CVPLAFVCDGENDCGDGSDES 2447 Score = 37.9 bits (84), Expect = 0.049 Identities = 16/32 (50%), Positives = 19/32 (59%), Gaps = 1/32 (3%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 F CD CI+ + CDG C DGSDE P +C Sbjct: 2931 FMCDNYRCISRLWRCDGEDDCGDGSDE-PDSC 2961 Score = 37.1 bits (82), Expect = 0.085 Identities = 16/33 (48%), Positives = 19/33 (57%), Gaps = 1/33 (3%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAACA 1180 F C G+CI VCDG C D SDE P+ C+ Sbjct: 52 FLCANGMCIPKSAVCDGENDCGDMSDE-PSNCS 83 Score = 33.9 bits (74), Expect = 0.79 Identities = 11/18 (61%), Positives = 14/18 (77%) Query: 1096 QCDGQQDCEDGRDEAECG 1113 +CDG +DC DG DE+ CG Sbjct: 106 RCDGMKDCADGSDESTCG 123 Score = 33.5 bits (73), Expect = 1.0 Identities = 21/88 (23%), Positives = 35/88 (39%), Gaps = 6/88 (6%) Query: 1 MVNTSRLTRITTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVS 60 M +SR + + G +DF N + W D I+ N G+ +++ Sbjct: 1649 MDGSSRRVIVHHMRMGYPNGLTIDFE--TNRLYWCDASKNTIETAKLN----GKNRRVIY 1702 Query: 61 EGLVTPTGIAIDWYTDKLYWTDGETNKI 88 +G P I Y D L+W+D +I Sbjct: 1703 QGNEVPHPFGISLYEDSLFWSDWTRKQI 1730 Score = 33.5 bits (73), Expect = 1.0 Identities = 24/78 (30%), Positives = 27/78 (34%), Gaps = 22/78 (28%) Query: 1097 CDGQQDCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEGLCI 1156 CDG C D DEA +C V C D F+C C+ Sbjct: 3306 CDGVYHCTDKSDEAPYRSCPARVACRK----------------------DQFKCLNRRCV 3343 Query: 1157 AARFVCDGRPQCADGSDE 1174 R VCD C D SDE Sbjct: 3344 PVRAVCDSNDDCGDISDE 3361 Score = 33.1 bits (72), Expect = 1.4 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 2/70 (2%) Query: 57 KIVSEGLVTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVP 116 +IV L P G+ + T KL+W D + + +E + R+ L + V Sbjct: 2776 RIVESKLAWPNGLTMCRITRKLFWVDAKRDVVEFANPDGTGRQQLALLHAPHPFGVTVYE 2835 Query: 117 EDGLMFWTDW 126 ++ ++WTDW Sbjct: 2836 DE--VYWTDW 2843 Score = 32.7 bits (71), Expect = 1.8 Identities = 14/28 (50%), Positives = 16/28 (57%), Gaps = 1/28 (3%) Query: 1148 FRCD-EGLCIAARFVCDGRPQCADGSDE 1174 F+C+ CI RFVCD C D SDE Sbjct: 1052 FQCETSSRCIPLRFVCDADDDCGDRSDE 1079 Score = 32.7 bits (71), Expect = 1.8 Identities = 17/36 (47%), Positives = 19/36 (52%), Gaps = 5/36 (13%) Query: 1092 AVSRQCDGQQDCEDGRDEAEC----GACG-GDVRCA 1122 A S CDG DC DG DE +C CG G RC+ Sbjct: 2510 ANSSVCDGDTDCADGSDEKDCDLGTSTCGAGLFRCS 2545 Score = 32.7 bits (71), Expect = 1.8 Identities = 33/153 (21%), Positives = 65/153 (42%), Gaps = 19/153 (12%) Query: 873 GCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE-----FLLFAQKNAVGRIMVA 927 GC+ C+ G ++C C YRL N +P +L+ A++ + M Sbjct: 2572 GCNQFCINLKGS----FKCTCAKGYRLEPRNRRICKPVNPPVLAYLIVAEQGGIVS-MDT 2626 Query: 928 NGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDD-SHSIRRVPISYXXXXXXXXXXXXX 986 NG + G + + A+++D VE ++YW + IRR ++ Sbjct: 2627 NGWQRKLLV--NGSEAI-AVDFDVVEGRVYWTQAGIAPQIRRAFLN-----GSHPEVVIQ 2678 Query: 987 XGLSRPYHMVLDVLGRTMYWTCADRDSINATSI 1019 G+ P + +D + R +Y++ +D I +++ Sbjct: 2679 AGVVTPEGIAVDWVARNLYFSDRVQDKIMVSTL 2711 Score = 31.9 bits (69), Expect = 3.2 Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 1/28 (3%) Query: 1148 FRCDEGL-CIAARFVCDGRPQCADGSDE 1174 F C G CI +++CDG C D SDE Sbjct: 1092 FACANGRHCIQRKWICDGENDCGDRSDE 1119 Score = 30.3 bits (65), Expect = 9.8 Identities = 11/17 (64%), Positives = 11/17 (64%) Query: 1097 CDGQQDCEDGRDEAECG 1113 CDG DC DG DE CG Sbjct: 929 CDGFDDCGDGSDEKGCG 945 Score = 30.3 bits (65), Expect = 9.8 Identities = 34/149 (22%), Positives = 52/149 (34%), Gaps = 10/149 (6%) Query: 939 TGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLD 998 +GL+ I DP+ +++W D R + L P + +D Sbjct: 3581 SGLEQPAGIAVDPISGRIFWTDGG----YRPKVMSSALDGTDPRSLVTSELISPAGLAID 3636 Query: 999 VLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGAI 1058 +YW I+A +D N V M P LA Y+ + + G + Sbjct: 3637 HASDVLYWADTRTGRIDAIGLDGNGRR--TVWSGLMQPYSLAVQGDWLYV--SGLRNGTV 3692 Query: 1059 MRANVDGTG--RVELARADNATALALDQS 1085 R + G G V L A LA+ QS Sbjct: 3693 YRMDKLGRGSPHVLLQGVGRAMPLAIVQS 3721 >SB_51898| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1712 Score = 377 bits (927), Expect = e-104 Identities = 205/553 (37%), Positives = 315/553 (56%), Gaps = 57/553 (10%) Query: 10 ITTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGI 69 +T + K+LE A+DF Y +N + W+D E I+ T E ++S GL P G+ Sbjct: 183 VTVVVKNLEDAIALDFDYEQNYVFWTDVLLEKIKRARIFGNNTQED--VISVGLKRPEGL 240 Query: 70 AIDWYTDKLYWTDGE--TNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWG 127 A+DW + KLYWTD E TN+IEV ++ ++RKVLFW + RAIAV P G MFWTDWG Sbjct: 241 AVDWCSKKLYWTDSEVETNRIEVSNMDGRFRKVLFWENLGQPRAIAVDPASGYMFWTDWG 300 Query: 128 EIPKIERAGMNGDPATRKVIVRD--------------NIFWPNG-----ITVDYNN---- 164 E PKIERAGM+G T ++ +D I+W + T D+N Sbjct: 301 EEPKIERAGMDGTQRT-VIVSKDIFWPNGLTIDHNDKRIYWTDAKQHHIATTDFNGKEKR 359 Query: 165 SLIYWV---DAKLQFVDVIDFNGEKRKRVVKGGLVYPFALTFSNDKLYWTDWQNWSIYTW 221 ++I + DFNG++++ +++G L +PFA++ +KLYWTDW SI++ Sbjct: 360 TIIRGTLPHPFAQHHIATTDFNGKEKRTIIRGTLPHPFAVSLYGNKLYWTDWTTKSIHSC 419 Query: 222 DIAANGPKIKELIKSHPVPADIKVYDESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYN 281 + ++K L + P I V++++RQ P P G + Sbjct: 420 NKKTGFGRLK-LQSNVYSPMGIHVFEKARQ----------------------DPLPKGIS 456 Query: 282 CACPTGVKLRENSSTTCYDSPQMLLVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVD 341 CACPTGV+L ++ T C + P+ L++A+R+ + +ISLD+PD T LP +K + VD Sbjct: 457 CACPTGVRLLLDNKT-CENGPKHFLLLARRTDLRRISLDTPDHTDVVLPFVGIKHGIAVD 515 Query: 342 FDPKTEYIYWADGLAKTISKARLDGSD-QSVVVRSSGVPDSIAIDPLSRKIYWTDPVMDT 400 FDP EYIYW+D + I +A +DG ++V P+ IA+D ++R +YWTD MD Sbjct: 516 FDPIEEYIYWSDDTLQVIKRAHIDGKGVETVASVEVQNPEGIAVDWIARNLYWTDTGMDR 575 Query: 401 INVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLI 460 I V+RL+G+ K++I +L++PRAI + G M+W+DW E PKIERA+LDG R++L+ Sbjct: 576 IEVSRLNGTSRKILISEDLWEPRAIVVDPGKGHMYWTDWGEH-PKIERADLDGGNRIILV 634 Query: 461 SEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERKELHSNDIIHIFGXXXXXXXX 520 + +TWPN + +D +NK+YW DA+ KIEV ++DG+ R+ + ++I H+FG Sbjct: 635 NSSVTWPNGLTIDYSDNKIYWADAKLDKIEVMDVDGSNRRVVLDSNIRHVFGLTLLGNYL 694 Query: 521 XXXXMQKRTLDRI 533 ++R +D + Sbjct: 695 YWTDWERRNIDML 707 Score = 310 bits (762), Expect = 3e-84 Identities = 232/828 (28%), Positives = 376/828 (45%), Gaps = 77/828 (9%) Query: 306 LVVAQRSTISKISLDSPDFTP-YTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARL 364 L+ A RS I + + TP T+ +K+L+ + +DFD + Y++W D L + I +AR+ Sbjct: 163 LIFANRSDIRILQTNGG--TPNVTVVVKNLEDAIALDFDYEQNYVFWTDVLLEKIKRARI 220 Query: 365 DGSDQSVVVRSSGV--PDSIAIDPLSRKIYWTDPVMDT--INVARLDGSYEKVIIHTELY 420 G++ V S G+ P+ +A+D S+K+YWTD ++T I V+ +DG + KV+ L Sbjct: 221 FGNNTQEDVISVGLKRPEGLAVDWCSKKLYWTDSEVETNRIEVSNMDGRFRKVLFWENLG 280 Query: 421 DPRAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLY 480 PRAIA+ +G+MFW+DW E+ PKIERA +DG+ R +++S+ + WPN + +D + ++Y Sbjct: 281 QPRAIAVDPASGYMFWTDWGEE-PKIERAGMDGTQRTVIVSKDIFWPNGLTIDHNDKRIY 339 Query: 481 WGDA---------------RT------------HKIEVCNMDGTERKELHSNDIIHIFGX 513 W DA RT H I + +G E++ + + H F Sbjct: 340 WTDAKQHHIATTDFNGKEKRTIIRGTLPHPFAQHHIATTDFNGKEKRTIIRGTLPHPFAV 399 Query: 514 XXXXXXXXXXXMQKRTLDRINKNTGLDRQPVVEQMANMMGVKAFRLGAPLGWNPCADDNG 573 +++ NK TG R + + + MG+ F +P Sbjct: 400 SLYGNKLYWTDWTTKSIHSCNKKTGFGRLKLQSNVYSPMGIHVFEKARQ---DPL----- 451 Query: 574 GCSHLCFNRPDDYICGCPLGLELTADKKTCVE-PEAFLVYSRKNIIGRLSIKN-EYNDAV 631 P C CP G+ L D KTC P+ FL+ +R+ + R+S+ ++ D V Sbjct: 452 ---------PKGISCACPTGVRLLLDNKTCENGPKHFLLLARRTDLRRISLDTPDHTDVV 502 Query: 632 IPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEW-LGLVEGLAIDWS 690 +P +K A+ +YWSD + I R ++G VE + + EG+A+DW Sbjct: 503 LPFVGIKHGIAVDFDPIEEYIYWSDDTLQVIKRAHIDGKGVETVASVEVQNPEGIAVDWI 562 Query: 691 GQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELGS-KSIKR 749 +N+YWTDT RIEVSRL+G+SR+ +I + L +P++IV+DP KG+MYW++ G I+R Sbjct: 563 ARNLYWTDTGMDRIEVSRLNGTSRKILISEDLWEPRAIVVDPGKGHMYWTDWGEHPKIER 622 Query: 750 AAMDGSS-VSVFMEQVGRVHALAIDYERRAIYWAALDPPVVEFAFLNGTGRQTLAD-NIP 807 A +DG + + + V + L IDY IYWA +E ++G+ R+ + D NI Sbjct: 623 ADLDGGNRIILVNSSVTWPNGLTIDYSDNKIYWADAKLDKIEVMDVDGSNRRVVLDSNIR 682 Query: 808 MPYALALFNDSVYWGDWNTGQIQQARKTDGSNRKSIRKDLDYISDLKLYHRAKSMG---S 864 + L L + +YW DW I ++ + + D + MG Sbjct: 683 HVFGLTLLGNYLYWTDWERRNIDMLISLQEERKEVLWNNCRIFKDSRPSTCPSLMGLTLV 742 Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFLLFAQKNAVGRI 924 Q V C + L G D N + + E + ++ R Sbjct: 743 RQIMVAVVTCVCIVLRVFGG--KDIPLV--GIKEANALDFSIEEKRIYWTDITLKSINRA 798 Query: 925 MVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXX 984 + NG N + + L+ + D + K LYW D H I Sbjct: 799 YL-NGS-NPEKLIIVDLEYPDGLAVDWIAKNLYWTDSRKHK-----IEVSRLDGQHRRTL 851 Query: 985 XXXGLSRPYHMVLDVLGRTMYWTCADRD-SINATSIDNNSSTGVIVRGDRMLPRHLAFHQ 1043 + P + LD + +YW +D SI+ ++D ++ T VI R P + Sbjct: 852 LYKDVWEPRSLTLDPVNGHLYWANGGQDSSIDRANMDGSNRTKVISNVKR--PTDITIDY 909 Query: 1044 TKRYLIWNDVGRGAIMRANVDGTGRVELARADNATALALDQSAGTVYW 1091 + L W D R I A++ G R +A+A AL Q +YW Sbjct: 910 KEGLLFWADSERKVIECADLHGRNRRTVAQA--TKPFALTQYLDYIYW 955 Score = 209 bits (510), Expect = 1e-53 Identities = 141/521 (27%), Positives = 244/521 (46%), Gaps = 65/521 (12%) Query: 610 LVYSRKNIIGRLSIKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNG 669 L+++ ++ I L + + +K+L++ AL + ++W+D + I R + G Sbjct: 163 LIFANRSDIRILQTNGGTPNVTVVVKNLEDAIALDFDYEQNYVFWTDVLLEKIKRARIFG 222 Query: 670 SAVEKIVEWLGLV--EGLAIDWSGQNIYWTDTT--TQRIEVSRLDGSSRRAIIWQGLKKP 725 + ++ V +GL EGLA+DW + +YWTD+ T RIEVS +DG R+ + W+ L +P Sbjct: 223 NNTQEDVISVGLKRPEGLAVDWCSKKLYWTDSEVETNRIEVSNMDGRFRKVLFWENLGQP 282 Query: 726 KSIVLDPKKGYMYWSELGSK-SIKRAAMDGSSVSVFMEQ-VGRVHALAIDY--------- 774 ++I +DP GYM+W++ G + I+RA MDG+ +V + + + + L ID+ Sbjct: 283 RAIAVDPASGYMFWTDWGEEPKIERAGMDGTQRTVIVSKDIFWPNGLTIDHNDKRIYWTD 342 Query: 775 --------------ERRAIYWAALDPPVVEFAF----LNGTGRQTLA-DNIPMPYALALF 815 E+R I L P + NG ++T+ +P P+A++L+ Sbjct: 343 AKQHHIATTDFNGKEKRTIIRGTLPHPFAQHHIATTDFNGKEKRTIIRGTLPHPFAVSLY 402 Query: 816 NDSVYWGDWNTGQIQQARKTDGSNRKSIRKDLDYISDLKLYHRAKSMGSNQCGVDNGGCS 875 + +YW DW T I K G R ++ ++ + ++ +A+ Sbjct: 403 GNKLYWTDWTTKSIHSCNKKTGFGRLKLQSNVYSPMGIHVFEKARQD------------- 449 Query: 876 HLCLPTPGDVRTDYRCACPAHYRLNKDNITCSE-PEEFLLFAQKNAVGRIMVANGECNDA 934 P P + CACP RL DN TC P+ FLL A++ + RI + + D Sbjct: 450 ----PLPKGIS----CACPTGVRLLLDNKTCENGPKHFLLLARRTDLRRISLDTPDHTDV 501 Query: 935 YIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYH 994 +P G+K+ A+++DP+E+ +YW DD I+R I + P Sbjct: 502 VLPFVGIKHGIAVDFDPIEEYIYWSDDTLQVIKRAHID-----GKGVETVASVEVQNPEG 556 Query: 995 MVLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVG 1054 + +D + R +YWT D I + + N +S +++ D PR + K ++ W D G Sbjct: 557 IAVDWIARNLYWTDTGMDRIEVSRL-NGTSRKILISEDLWEPRAIVVDPGKGHMYWTDWG 615 Query: 1055 -RGAIMRANVDGTGRVELARADNA--TALALDQSAGTVYWA 1092 I RA++DG R+ L + L +D S +YWA Sbjct: 616 EHPKIERADLDGGNRIILVNSSVTWPNGLTIDYSDNKIYWA 656 Score = 198 bits (483), Expect = 2e-50 Identities = 94/231 (40%), Positives = 145/231 (62%), Gaps = 3/231 (1%) Query: 632 IPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEK-IVEWLGLVEGLAIDWS 690 IP+ +KE +AL + ++YW+D K+INR +NGS EK I+ L +GLA+DW Sbjct: 765 IPLVGIKEANALDFSIEEKRIYWTDITLKSINRAYLNGSNPEKLIIVDLEYPDGLAVDWI 824 Query: 691 GQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELG-SKSIKR 749 +N+YWTD+ +IEVSRLDG RR ++++ + +P+S+ LDP G++YW+ G SI R Sbjct: 825 AKNLYWTDSRKHKIEVSRLDGQHRRTLLYKDVWEPRSLTLDPVNGHLYWANGGQDSSIDR 884 Query: 750 AAMDGSSVSVFMEQVGRVHALAIDYERRAIYWAALDPPVVEFAFLNGTGRQTLADNIPMP 809 A MDGS+ + + V R + IDY+ ++WA + V+E A L+G R+T+A P Sbjct: 885 ANMDGSNRTKVISNVKRPTDITIDYKEGLLFWADSERKVIECADLHGRNRRTVA-QATKP 943 Query: 810 YALALFNDSVYWGDWNTGQIQQARKTDGSNRKSIRKDLDYISDLKLYHRAK 860 +AL + D +YW DW T I++A KT G NR IR +DY+ D+ ++H ++ Sbjct: 944 FALTQYLDYIYWTDWETESIERANKTTGLNRTRIRSRVDYVMDITVFHSSR 994 Score = 161 bits (391), Expect = 3e-39 Identities = 136/508 (26%), Positives = 231/508 (45%), Gaps = 41/508 (8%) Query: 17 LEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIAIDWYTD 76 +++ A+DF + I W+D + I N + EK IV L P G+A+DW Sbjct: 770 IKEANALDFSIEEKRIYWTDITLKSINRAYLNGS-NPEKLIIVD--LEYPDGLAVDWIAK 826 Query: 77 KLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIPKIERAG 136 LYWTD +KIEV + ++R+ L + +V R++ + P +G ++W + G+ I+RA Sbjct: 827 NLYWTDSRKHKIEVSRLDGQHRRTLLYKDVWEPRSLTLDPVNGHLYWANGGQDSSIDRAN 886 Query: 137 MNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVVKGGLV 196 M+G T KVI N+ P IT+DY L++W D++ + ++ D +G R+ V + Sbjct: 887 MDGSNRT-KVI--SNVKRPTDITIDYKEGLLFWADSERKVIECADLHGRNRRTVAQA--T 941 Query: 197 YPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIKVYDESRQIISAE 256 PFALT D +YWTDW+ SI + G + DI V+ SRQ Sbjct: 942 KPFALTQYLDYIYWTDWETESIERAN-KTTGLNRTRIRSRVDYVMDITVFHSSRQ-EEPL 999 Query: 257 DYPCKKNNAGCSHLCLLSPDPPGYNCACPT--GVKLRENSSTTCY----DSPQMLLVVA- 309 + G S D + VK +T + D+ + + A Sbjct: 1000 SFMLYSTVKGIHRFIFDSTDYAEISLPLRKLHDVKAVSYDISTGFVYWIDAVEGTIRRAL 1059 Query: 310 QRSTISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQ 369 + ++S + + PD PY L + DP + ++W D + I+ L Sbjct: 1060 ENGSLSGVIVAGPDVEPYDLAI-----------DPYGQQMFWTDAVRNEINVFSLKKMAP 1108 Query: 370 SVVVRSS--GVPDSIAIDPLSRKIYWTDPVMDTINVAR--LDGSYEKVIIHTELYDPRAI 425 VV S+ +P SI + P ++WTD + + R +DGS+ + I+ P + Sbjct: 1109 LGVVASAKDEMPRSIVLFPEKGLMFWTDVGKNGPKILRASMDGSFPQPIVSNIPRSPVGL 1168 Query: 426 ALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDAR 485 A+ ++W+D K KIE ++L G+ R +L+ L P +A+ + +YW D+R Sbjct: 1169 AVDTDRDKLYWTDTAHK--KIEFSDLQGAKRTVLVDTNLLTPIGLAIH--GDFVYWIDSR 1224 Query: 486 THKI-----EVCNMDGTERKELHSNDII 508 + EV + + T + E+ D++ Sbjct: 1225 ARVLKRVRREVGSDEQTIQAEIDVTDLV 1252 Score = 151 bits (366), Expect = 3e-36 Identities = 92/312 (29%), Positives = 152/312 (48%), Gaps = 8/312 (2%) Query: 300 DSPQMLLVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTI 359 + P ++ + I + DS D+ +LPL+ L V +D T ++YW D + TI Sbjct: 996 EEPLSFMLYSTVKGIHRFIFDSTDYAEISLPLRKLHDVKAVSYDISTGFVYWIDAVEGTI 1055 Query: 360 SKARLDGSDQSVVVRSSGV-PDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTE 418 +A +GS V+V V P +AIDP ++++WTD V + INV L ++ + Sbjct: 1056 RRALENGSLSGVIVAGPDVEPYDLAIDPYGQQMFWTDAVRNEINVFSLKKMAPLGVVASA 1115 Query: 419 LYD-PRAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNN 477 + PR+I L G MFW+D + PKI RA++DGS ++S P +A+DT + Sbjct: 1116 KDEMPRSIVLFPEKGLMFWTDVGKNGPKILRASMDGSFPQPIVSNIPRSPVGLAVDTDRD 1175 Query: 478 KLYWGDARTHKIEVCNMDGTERKELHSNDIIHIFGXXXXXXXXXXXXMQKRTLDRINKNT 537 KLYW D KIE ++ G +R L +++ G + R L R+ + Sbjct: 1176 KLYWTDTAHKKIEFSDLQGAKRTVLVDTNLLTPIGLAIHGDFVYWIDSRARVLKRVRREV 1235 Query: 538 GLDRQPVVEQ--MANMMGVKAFRLGAPLGWNPCADDNGGCSHLC-FNRPDDYICGCPLGL 594 G D Q + + + +++ + ++ + +PC ++ CSH+C R + C C L Sbjct: 1236 GSDEQTIQAEIDVTDLVALDRSQISGTVP-HPCKQND--CSHICLIGRDNAAKCSCTGSL 1292 Query: 595 ELTADKKTCVEP 606 L D+K C EP Sbjct: 1293 VLQDDEKNCGEP 1304 Score = 151 bits (366), Expect = 3e-36 Identities = 98/312 (31%), Positives = 155/312 (49%), Gaps = 11/312 (3%) Query: 605 EPEAFLVYSRKNIIGRLSIKN-EYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTIN 663 EP +F++YS I R + +Y + +P++ L +V A++ +S +YW D+ TI Sbjct: 997 EPLSFMLYSTVKGIHRFIFDSTDYAEISLPLRKLHDVKAVSYDISTGFVYWIDAVEGTIR 1056 Query: 664 RCSVNGSAVEKIVEWLGLVE-GLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGL 722 R NGS IV + LAID GQ ++WTD I V L + ++ Sbjct: 1057 RALENGSLSGVIVAGPDVEPYDLAIDPYGQQMFWTDAVRNEINVFSLKKMAPLGVVASAK 1116 Query: 723 KK-PKSIVLDPKKGYMYWSELGSKSIK--RAAMDGSSVSVFMEQVGRVHA-LAIDYERRA 778 + P+SIVL P+KG M+W+++G K RA+MDGS + + R LA+D +R Sbjct: 1117 DEMPRSIVLFPEKGLMFWTDVGKNGPKILRASMDGSFPQPIVSNIPRSPVGLAVDTDRDK 1176 Query: 779 IYWAALDPPVVEFAFLNGTGRQTLAD-NIPMPYALALFNDSVYWGDWNTGQIQQARKTDG 837 +YW +EF+ L G R L D N+ P LA+ D VYW D +++ R+ G Sbjct: 1177 LYWTDTAHKKIEFSDLQGAKRTVLVDTNLLTPIGLAIHGDFVYWIDSRARVLKRVRREVG 1236 Query: 838 SNRKSIRKDLDYISDLKLYHRAKSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHY 897 S+ ++I+ ++D ++DL R++ G+ CSH+CL + +C+C Sbjct: 1237 SDEQTIQAEID-VTDLVALDRSQISGTVPHPCKQNDCSHICLIGRDNAA---KCSCTGSL 1292 Query: 898 RLNKDNITCSEP 909 L D C EP Sbjct: 1293 VLQDDEKNCGEP 1304 Score = 150 bits (363), Expect = 8e-36 Identities = 110/463 (23%), Positives = 213/463 (46%), Gaps = 17/463 (3%) Query: 329 LPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSD-QSVVVRSSGVPDSIAIDPL 387 +PL +K +DF + + IYW D K+I++A L+GS+ + +++ PD +A+D + Sbjct: 765 IPLVGIKEANALDFSIEEKRIYWTDITLKSINRAYLNGSNPEKLIIVDLEYPDGLAVDWI 824 Query: 388 SRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKPKIE 447 ++ +YWTD I V+RLDG + + +++ ++++PR++ L G ++W++ + I+ Sbjct: 825 AKNLYWTDSRKHKIEVSRLDGQHRRTLLYKDVWEPRSLTLDPVNGHLYWANGGQDS-SID 883 Query: 448 RANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERKELHSNDI 507 RAN+DGS R +IS + P I +D L+W D+ IE ++ G R+ + Sbjct: 884 RANMDGSNRTKVIS-NVKRPTDITIDYKEGLLFWADSERKVIECADLHGRNRRTV--AQA 940 Query: 508 IHIFGXXXXXXXXXXXXMQKRTLDRINKNTGLDRQPVVEQMANMMGVKAF---RLGAPLG 564 F + +++R NK TGL+R + ++ +M + F R PL Sbjct: 941 TKPFALTQYLDYIYWTDWETESIERANKTTGLNRTRIRSRVDYVMDITVFHSSRQEEPLS 1000 Query: 565 WNPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYSRKNIIG--RLS 622 + + G F+ D PL +L K + VY + G R + Sbjct: 1001 FMLYSTVK-GIHRFIFDSTDYAEISLPL-RKLHDVKAVSYDISTGFVYWIDAVEGTIRRA 1058 Query: 623 IKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEWL--G 680 ++N VI E LA+ G +++W+D+ IN S+ A +V Sbjct: 1059 LENGSLSGVIVAGPDVEPYDLAIDPYGQQMFWTDAVRNEINVFSLKKMAPLGVVASAKDE 1118 Query: 681 LVEGLAIDWSGQNIYWTDTTTQRIEVSR--LDGSSRRAIIWQGLKKPKSIVLDPKKGYMY 738 + + + ++WTD ++ R +DGS + I+ + P + +D + +Y Sbjct: 1119 MPRSIVLFPEKGLMFWTDVGKNGPKILRASMDGSFPQPIVSNIPRSPVGLAVDTDRDKLY 1178 Query: 739 WSELGSKSIKRAAMDGSSVSVFMEQVGRVHALAIDYERRAIYW 781 W++ K I+ + + G+ +V ++ + + + +YW Sbjct: 1179 WTDTAHKKIEFSDLQGAKRTVLVD-TNLLTPIGLAIHGDFVYW 1220 Score = 115 bits (277), Expect = 2e-25 Identities = 85/286 (29%), Positives = 137/286 (47%), Gaps = 14/286 (4%) Query: 15 KDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIAIDWY 74 + L AV + + W D I+ N + +G IV+ V P +AID Y Sbjct: 1028 RKLHDVKAVSYDISTGFVYWIDAVEGTIRRALENGSLSGV---IVAGPDVEPYDLAIDPY 1084 Query: 75 TDKLYWTDGETNKIEVISIVQKY-RKVLFWSEVDLARAIAVVPEDGLMFWTDWGEI-PKI 132 +++WTD N+I V S+ + V+ ++ ++ R+I + PE GLMFWTD G+ PKI Sbjct: 1085 GQQMFWTDAVRNEINVFSLKKMAPLGVVASAKDEMPRSIVLFPEKGLMFWTDVGKNGPKI 1144 Query: 133 ERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVVK 192 RA M+G + + IV + P G+ VD + +YW D + ++ D G KR +V Sbjct: 1145 LRASMDG--SFPQPIVSNIPRSPVGLAVDTDRDKLYWTDTAHKKIEFSDLQGAKRTVLVD 1202 Query: 193 GGLVYPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIKVYDESRQI 252 L+ P L D +YW D + + + ++ I++ D+ D S QI Sbjct: 1203 TNLLTPIGLAIHGDFVYWIDSRARVLKR--VRREVGSDEQTIQAEIDVTDLVALDRS-QI 1259 Query: 253 ISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTC 298 +PCK+N+ CSH+CL+ D C+C TG + ++ C Sbjct: 1260 SGTVPHPCKQND--CSHICLIGRDNAA-KCSC-TGSLVLQDDEKNC 1301 Score = 115 bits (276), Expect = 3e-25 Identities = 94/428 (21%), Positives = 184/428 (42%), Gaps = 21/428 (4%) Query: 674 KIVEWLGLVEGLAIDWS--GQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLD 731 K + +G+ E A+D+S + IYWTD T + I + L+GS+ +I L+ P + +D Sbjct: 763 KDIPLVGIKEANALDFSIEEKRIYWTDITLKSINRAYLNGSNPEKLIIVDLEYPDGLAVD 822 Query: 732 PKKGYMYWSELGSKSIKRAAMDGSSVSVFM-EQVGRVHALAIDYERRAIYWA-ALDPPVV 789 +YW++ I+ + +DG + + V +L +D +YWA + Sbjct: 823 WIAKNLYWTDSRKHKIEVSRLDGQHRRTLLYKDVWEPRSLTLDPVNGHLYWANGGQDSSI 882 Query: 790 EFAFLNGTGRQTLADNIPMPYALAL-FNDSV-YWGDWNTGQIQQARKTDGSNRKSIRKDL 847 + A ++G+ R + N+ P + + + + + +W D + ++ + G NR+++ + Sbjct: 883 DRANMDGSNRTKVISNVKRPTDITIDYKEGLLFWAD-SERKVIECADLHGRNRRTVAQAT 941 Query: 848 DYISDLKLYHRAKSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCS 907 + + ++ + T R DY + ++ Sbjct: 942 KPFALTQYLDYIYWTDWETESIERANKTTGLNRTRIRSRVDYVMDITVFHSSRQE----- 996 Query: 908 EPEEFLLFAQKNAVGRIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIR 967 EP F+L++ + R + + + + +PL L +V+A+ YD +YW+D +IR Sbjct: 997 EPLSFMLYSTVKGIHRFIFDSTDYAEISLPLRKLHDVKAVSYDISTGFVYWIDAVEGTIR 1056 Query: 968 RVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSSTGV 1027 R + PY + +D G+ M+WT A R+ IN S+ + GV Sbjct: 1057 RALENGSLSGVIVAGPDV-----EPYDLAIDPYGQQMFWTDAVRNEINVFSLKKMAPLGV 1111 Query: 1028 IVRGDRMLPRHLAFHQTKRYLIWNDVGRGA--IMRANVDGTGRVELAR--ADNATALALD 1083 + +PR + K + W DVG+ I+RA++DG+ + + LA+D Sbjct: 1112 VASAKDEMPRSIVLFPEKGLMFWTDVGKNGPKILRASMDGSFPQPIVSNIPRSPVGLAVD 1171 Query: 1084 QSAGTVYW 1091 +YW Sbjct: 1172 TDRDKLYW 1179 Score = 70.1 bits (164), Expect = 1e-11 Identities = 42/163 (25%), Positives = 76/163 (46%), Gaps = 8/163 (4%) Query: 936 IPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHM 995 IPL G+K A+++ EK++YW D SI R ++ L P + Sbjct: 765 IPLVGIKEANALDFSIEEKRIYWTDITLKSINRAYLN-----GSNPEKLIIVDLEYPDGL 819 Query: 996 VLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGR 1055 +D + + +YWT + + I + +D ++ + D PR L +L W + G+ Sbjct: 820 AVDWIAKNLYWTDSRKHKIEVSRLDGQHRRTLLYK-DVWEPRSLTLDPVNGHLYWANGGQ 878 Query: 1056 -GAIMRANVDGTGRVE-LARADNATALALDQSAGTVYWAVSRQ 1096 +I RAN+DG+ R + ++ T + +D G ++WA S + Sbjct: 879 DSSIDRANMDGSNRTKVISNVKRPTDITIDYKEGLLFWADSER 921 Score = 64.9 bits (151), Expect = 4e-10 Identities = 52/174 (29%), Positives = 86/174 (49%), Gaps = 11/174 (6%) Query: 19 QGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIAIDWYTDKL 78 +G AVD+ R + W+D + I+ N T + ++SE L P I +D + Sbjct: 555 EGIAVDWIARN--LYWTDTGMDRIEVSRLNGT---SRKILISEDLWEPRAIVVDPGKGHM 609 Query: 79 YWTD-GETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIPKIERAGM 137 YWTD GE KIE + R +L S V + + D ++W D ++ KIE M Sbjct: 610 YWTDWGEHPKIERADLDGGNRIILVNSSVTWPNGLTIDYSDNKIYWAD-AKLDKIEV--M 666 Query: 138 NGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVV 191 + D + R+V++ NI G+T+ N +YW D + + +D++ E+RK V+ Sbjct: 667 DVDGSNRRVVLDSNIRHVFGLTLLGN--YLYWTDWERRNIDMLISLQEERKEVL 718 Score = 62.5 bits (145), Expect = 2e-09 Identities = 46/189 (24%), Positives = 85/189 (44%), Gaps = 11/189 (5%) Query: 913 LLFAQKNAVGRIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPIS 972 L+FA ++ + RI+ NG + + + L++ A+++D + ++W D I+R I Sbjct: 163 LIFANRSDI-RILQTNGGTPNVTVVVKNLEDAIALDFDYEQNYVFWTDVLLEKIKRARI- 220 Query: 973 YXXXXXXXXXXXXXXGLSRPYHMVLDVLGRTMYWTCADRDS--INATSIDNNSSTGVIVR 1030 GL RP + +D + +YWT ++ ++ I +++D V+ Sbjct: 221 ---FGNNTQEDVISVGLKRPEGLAVDWCSKKLYWTDSEVETNRIEVSNMDGRFRK-VLFW 276 Query: 1031 GDRMLPRHLAFHQTKRYLIWNDVG-RGAIMRANVDGTGRVELARADN--ATALALDQSAG 1087 + PR +A Y+ W D G I RA +DGT R + D L +D + Sbjct: 277 ENLGQPRAIAVDPASGYMFWTDWGEEPKIERAGMDGTQRTVIVSKDIFWPNGLTIDHNDK 336 Query: 1088 TVYWAVSRQ 1096 +YW ++Q Sbjct: 337 RIYWTDAKQ 345 Score = 58.8 bits (136), Expect = 2e-08 Identities = 106/498 (21%), Positives = 193/498 (38%), Gaps = 36/498 (7%) Query: 9 RITTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTG 68 RI + + + Y N I W+D K + I+ M+ + G ++V + + Sbjct: 630 RIILVNSSVTWPNGLTIDYSDNKIYWADAKLDKIEVMDVD----GSNRRVVLDSNIRHV- 684 Query: 69 IAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGE 128 + + LYWTD E I+++ +Q+ RK + W+ + + LM T + Sbjct: 685 FGLTLLGNYLYWTDWERRNIDMLISLQEERKEVLWNNCRIFKDSRPSTCPSLMGLTLVRQ 744 Query: 129 I--PKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEK 186 I + + K I I N + IYW D L+ ++ NG Sbjct: 745 IMVAVVTCVCIVLRVFGGKDIPLVGIKEANALDFSIEEKRIYWTDITLKSINRAYLNGSN 804 Query: 187 RKRVVKGGLVYP--FALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIK 244 ++++ L YP A+ + LYWTD + I + + L K P + Sbjct: 805 PEKLIIVDLEYPDGLAVDWIAKNLYWTDSRKHKIEVSRLDGQHRRTL-LYKDVWEPRSLT 863 Query: 245 VYDESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQM 304 + + + A N S + + D G N R T Y + Sbjct: 864 LDPVNGHLYWA-------NGGQDSSIDRANMD--GSNRTKVISNVKRPTDITIDYKEGLL 914 Query: 305 LLVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVDF----DPKTEYIYWAD---GLAK 357 ++R I L + K T +D+ D +TE I A+ GL + Sbjct: 915 FWADSERKVIECADLHGRNRRTVAQATKPFALTQYLDYIYWTDWETESIERANKTTGLNR 974 Query: 358 TISKARLDGSDQSVVVRSSGVPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIH- 416 T ++R+D V SS +PLS +Y T + D Y ++ + Sbjct: 975 TRIRSRVDYVMDITVFHSSRQE-----EPLSFMLYSTVKGIHRFIFDSTD--YAEISLPL 1027 Query: 417 TELYDPRAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVN 476 +L+D +A++ ++ G+++W D E I RA +GS ++++ P +A+D Sbjct: 1028 RKLHDVKAVSYDISTGFVYWIDAVE--GTIRRALENGSLSGVIVAGPDVEPYDLAIDPYG 1085 Query: 477 NKLYWGDARTHKIEVCNM 494 +++W DA ++I V ++ Sbjct: 1086 QQMFWTDAVRNEINVFSL 1103 Score = 51.6 bits (118), Expect = 4e-06 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 11/108 (10%) Query: 1096 QCDGQQDCEDGRDEAECGACGGDV------RCADGTXXXXXXXXXXXXXXXXXXXX---D 1146 +CDG DC D DE +C C + +C DG + Sbjct: 1327 RCDGMLDCTDKSDEEDCPPCKENQFRCDNGQCIDGDPRCDKYKNCTDGSDELGCATCEPN 1386 Query: 1147 AFRCDEGLCIAARFVCDGRPQCADGSDEAPAACAYGHTDQVNGIHPPL 1194 FRC+ G CI+AR+ CD C D SDE C + N HPP+ Sbjct: 1387 FFRCNTGKCISARWQCDQLDDCGDNSDE--IGCDTPPGNGTNANHPPV 1432 Score = 35.1 bits (77), Expect = 0.34 Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 4/78 (5%) Query: 138 NGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVID-FNGEKRKRVVKGGLV 196 NG V+V+ N+ + DY + ++W D L+ + F ++ V+ GL Sbjct: 177 NGGTPNVTVVVK-NLEDAIALDFDYEQNYVFWTDVLLEKIKRARIFGNNTQEDVISVGLK 235 Query: 197 YP--FALTFSNDKLYWTD 212 P A+ + + KLYWTD Sbjct: 236 RPEGLAVDWCSKKLYWTD 253 >SB_17350| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2956 Score = 281 bits (689), Expect = 2e-75 Identities = 176/577 (30%), Positives = 286/577 (49%), Gaps = 39/577 (6%) Query: 8 TRITTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPT 67 T IT + +L+ A+D R I WSD + + I+ + T+ + I++ + Sbjct: 1028 TTITPVIFNLDSAVALDVDVRDRRIYWSDTRTKAIKRAQIDGTFIED---IITTNIGVCD 1084 Query: 68 GIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWG 127 G+AI+W T ++YWTD I+V ++ R VL S +D R IAV P+ GLMFWTDWG Sbjct: 1085 GLAIEWRTRRIYWTDRTYRFIQVATLDGSRRHVLISSGLDKPRGIAVHPQAGLMFWTDWG 1144 Query: 128 EIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKR 187 E PKIERA ++G R+ IV NI WPN I VDY + ++WVDA ++ D +G R Sbjct: 1145 ENPKIERARLDGQ--KRQEIVTSNIGWPNSIAVDYAANRLFWVDAIRDSLESSDLDGRAR 1202 Query: 188 KRVVKGGLVYPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIKVYD 247 + + + + PF ++ +YW+DW + I+ + G K + +P + V+D Sbjct: 1203 RTLFRQPGLQPFGVSILGKHVYWSDWASEGIH-MNRMGTGKLEKSVYNVGNMPMGVAVFD 1261 Query: 248 ESRQ-----IISAEDYPCKKNNAGCSHLCL------LSPDPPGYNCACP--------TGV 288 +SRQ I+ ++ +N C+ L+ PG C CP G Sbjct: 1262 KSRQPPEQLTITTQETTLAQNKMAVVATCVCQARQELNAHAPGRVC-CPVITSRVLKVGY 1320 Query: 289 KLRENSSTTC---YDSPQ-----MLLVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTV 340 R S D P ML+ + I KI LD P+ L + + T + Sbjct: 1321 VARVGQSVVVNWFRDMPASSEIFMLVSDPEIPAIYKIYLDVPNHNRGVLSVNE---TTDI 1377 Query: 341 DFDPKTEYIYWADGLAKTISKARLDGSDQSVVVRSSGVPDSIAIDPLSRKIYWTDPVMDT 400 +D + IYW DG + I +A ++ ++ + P+S+A+D L R +YWTD Sbjct: 1378 TYDHFEDRIYWIDGAQRNIHRAYMNMTEHEQFGMYTVRPESLALDWLGRHLYWTDAGTKR 1437 Query: 401 INVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLI 460 I A+LD + +I L PR + L G MFW+DW KPKIE++N+DG+ R L+ Sbjct: 1438 IEAAQLDTGIQAPVIMAGLDKPRGLVLDPPNGHMFWTDWG-SKPKIEKSNMDGTSRWTLL 1496 Query: 461 SEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERKELHSNDIIHIFGXXXXXXXX 520 + L WPN++ +D + +L+W DA+ ++IEVC+ G RK + +H FG Sbjct: 1497 DKDLIWPNALTIDYQSKRLFWADAKLNRIEVCDWYGENRKPVFEKRGMHPFGMAFFGDKL 1556 Query: 521 XXXXMQKRTLDRINKNTGLDRQPVVEQMANMMGVKAF 557 + +++ ++ ++G+ + P V +++ G+ + Sbjct: 1557 YWTDYKTKSVQELSLSSGVSK-PFVRRLSFPRGLYVY 1592 Score = 261 bits (639), Expect = 3e-69 Identities = 212/813 (26%), Positives = 364/813 (44%), Gaps = 57/813 (7%) Query: 67 TGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDW 126 T I D + D++YW DG I + + F ++A+ ++WTD Sbjct: 1375 TDITYDHFEDRIYWIDGAQRNIHR-AYMNMTEHEQFGMYTVRPESLALDWLGRHLYWTDA 1433 Query: 127 GEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVD-AKLQFVDVIDFNGE 185 G +IE A + D + ++ + P G+ +D N ++W D ++ + +G Sbjct: 1434 GT-KRIEAAQL--DTGIQAPVIMAGLDKPRGLVLDPPNGHMFWTDWGSKPKIEKSNMDGT 1490 Query: 186 KRKRVVKGGLVYPFALT--FSNDKLYWTDWQNWSIYTWD-IAANGPKIKELIKSHPVPAD 242 R ++ L++P ALT + + +L+W D + I D N + E HP Sbjct: 1491 SRWTLLDKDLIWPNALTIDYQSKRLFWADAKLNRIEVCDWYGENRKPVFEKRGMHPF--G 1548 Query: 243 IKVYDESRQIISAEDYPCKKNNAGCSHLCLLS--PDPPGYNCACPTGVKLRENSSTTCYD 300 + + + + DY K L L S P + P G+ + + S T Sbjct: 1549 MAFFGDK---LYWTDYKTKS----VQELSLSSGVSKPFVRRLSFPRGLYVYDPS--TYKT 1599 Query: 301 SPQMLLVV-AQRSTISKISLDSPD-FTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKT 358 + + LL + A +++ + LD + +TP ++ + +D+DP + I+W D T Sbjct: 1600 AKEFLLFIDAIAVSLNILPLDDTNIWTPVSVLPGKAVQPADLDYDPVEDAIFWTDTFTGT 1659 Query: 359 ISKARLDGSDQSVVVRSSGV--PDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIH 416 I+ + + +S+ + V PD I +D + R +YWTD I V+RLDG+ KV+I Sbjct: 1660 INSYNMQ-TRKSMTLHRCNVERPDGIGVDWIGRNLYWTDSGKGRIEVSRLDGTARKVLIQ 1718 Query: 417 TELYDPRAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVN 476 +L P A+ L G MF+SD + PK+E+A +DG+ R+ + K+T P S+ +D + Sbjct: 1719 DDLERPTALVLFPEEGTMFFSDCGSR-PKMEKAYMDGTSRITFVDRKITCPTSLNIDRQS 1777 Query: 477 NKLYWGDARTHKIEVCNMDGTERKELHSNDIIHIFGXXXXXXXXXXXXMQKRTLDRINKN 536 ++YW D I +G R+ + +G ++ + +++ Sbjct: 1778 ERIYWLDDNRDGIWSVFFNGANREVTYFERGTFPWGITLSGLITFVSDWKRGNIYKLSIE 1837 Query: 537 TGLDRQ-PVVEQMANMMGVKAFRLGA-PLGWNPCADDNGGCSHLCFNRPDDYICGCPLGL 594 T ++ V E++ ++ + + C+ +NGGCS LC RP C C G+ Sbjct: 1838 TNVELNITVAEEIKKPTAIRYYNQSRYNFVESQCSQNNGGCSDLCLLRPHSRTCACATGV 1897 Query: 595 ELTADKKTC-------VEPEAFLVYSRKNI---------IGRLSIKNEYNDAVIPIKDLK 638 L+ D+KTC E +L+ S I + YN+ + + Sbjct: 1898 PLSPDEKTCDHAVFNGQSNERYLLISDLQYRDVFKVPLHISDFPCLSLYNNPRTDLPEQS 1957 Query: 639 EVSALALYVSGSKL-YWSDSKTKTINRCSVNGSAVEKIVEWLGLV--EGLAIDWSGQNIY 695 V+A +Y +L YW+D + + R S++ S E I + G++ +G+ +D+ N+Y Sbjct: 1958 PVAASVVYNPRDRLIYWTDERRGAVMRASLDDSFREVIAD-KGIISPDGIDVDYISGNVY 2016 Query: 696 WTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELGSK-SIKRAAMDG 754 WTD RIEV+ LDG R + KP +IVLDP +G MYW++ G+ I A MDG Sbjct: 2017 WTDPKRGRIEVASLDGKDRLTLTGWSPDKPGAIVLDPVEGRMYWADYGTNPKIMTAHMDG 2076 Query: 755 SSVSVFM-EQVGRVHALAIDYERRAIYWAALDPPVVEFAFLNGTGRQTLAD-NI-----P 807 S+ + M + LAID+ R +YW + +E LNG R ++ D N Sbjct: 2077 SNRKILMGVGINITTGLAIDFRFRRLYWCDMGTGKIESMSLNGGNRISVYDLNAGRKFRA 2136 Query: 808 MPYALALFNDSVYWGDWNTGQIQQARKTDGSNR 840 P+ LA +YW D G + + G+ R Sbjct: 2137 RPFGLAFSKGKLYWADMMAGTVYELEVATGTTR 2169 Score = 230 bits (562), Expect = 6e-60 Identities = 154/512 (30%), Positives = 240/512 (46%), Gaps = 25/512 (4%) Query: 3 NTSRLTRITTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEG 62 +T+ T ++ + Q +D+ ++ I W+D I N T + + Sbjct: 1621 DTNIWTPVSVLPGKAVQPADLDYDPVEDAIFWTDTFTGTINSYNMQ---TRKSMTLHRCN 1677 Query: 63 LVTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMF 122 + P GI +DW LYWTD +IEV + RKVL +++ A+ + PE+G MF Sbjct: 1678 VERPDGIGVDWIGRNLYWTDSGKGRIEVSRLDGTARKVLIQDDLERPTALVLFPEEGTMF 1737 Query: 123 WTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDF 182 ++D G PK+E+A M+G +R V I P + +D + IYW+D + + F Sbjct: 1738 FSDCGSRPKMEKAYMDG--TSRITFVDRKITCPTSLNIDRQSERIYWLDDNRDGIWSVFF 1795 Query: 183 NGEKRKRVVKGGLVYPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPAD 242 NG R+ +P+ +T S + +DW+ +IY I N + + P Sbjct: 1796 NGANREVTYFERGTFPWGITLSGLITFVSDWKRGNIYKLSIETNVELNITVAEEIKKPTA 1855 Query: 243 IKVYDESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCY--- 299 I+ Y++SR + + C +NN GCS LCLL P CAC TGV L + T + Sbjct: 1856 IRYYNQSR--YNFVESQCSQNNGGCSDLCLLRPH--SRTCACATGVPLSPDEKTCDHAVF 1911 Query: 300 --DSPQMLLVVA--QRSTISKISL---DSPDFTPYTLPLKDLKR----TLTVDFDPKTEY 348 S + L+++ Q + K+ L D P + Y P DL +V ++P+ Sbjct: 1912 NGQSNERYLLISDLQYRDVFKVPLHISDFPCLSLYNNPRTDLPEQSPVAASVVYNPRDRL 1971 Query: 349 IYWADGLAKTISKARLDGSDQSVVVRSSGV-PDSIAIDPLSRKIYWTDPVMDTINVARLD 407 IYW D + +A LD S + V+ + PD I +D +S +YWTDP I VA LD Sbjct: 1972 IYWTDERRGAVMRASLDDSFREVIADKGIISPDGIDVDYISGNVYWTDPKRGRIEVASLD 2031 Query: 408 GSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWP 467 G + P AI L G M+W+D+ PKI A++DGS R +L+ + Sbjct: 2032 GKDRLTLTGWSPDKPGAIVLDPVEGRMYWADYG-TNPKIMTAHMDGSNRKILMGVGINIT 2090 Query: 468 NSIALDTVNNKLYWGDARTHKIEVCNMDGTER 499 +A+D +LYW D T KIE +++G R Sbjct: 2091 TGLAIDFRFRRLYWCDMGTGKIESMSLNGGNR 2122 Score = 198 bits (484), Expect = 2e-50 Identities = 198/768 (25%), Positives = 335/768 (43%), Gaps = 52/768 (6%) Query: 359 ISKARLDGSDQSVVVRSSGVPDSIAIDPLSRKIYWTDPVMDTINVARLDGS-YEKVIIHT 417 I K LD + + V S I D +IYW D I+ A ++ + +E+ ++T Sbjct: 1354 IYKIYLDVPNHNRGVLSVNETTDITYDHFEDRIYWIDGAQRNIHRAYMNMTEHEQFGMYT 1413 Query: 418 ELYDPRAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNN 477 P ++AL ++W+D K+ IE A LD + +I L P + LD N Sbjct: 1414 --VRPESLALDWLGRHLYWTDAGTKR--IEAAQLDTGIQAPVIMAGLDKPRGLVLDPPNG 1469 Query: 478 KLYWGD-ARTHKIEVCNMDGTERKELHSNDIIHIFGXXXXXXXXXXXXMQKRTLDRINKN 536 ++W D KIE NMDGT R L D+I + L+RI Sbjct: 1470 HMFWTDWGSKPKIEKSNMDGTSRWTLLDKDLIWPNALTIDYQSKRLFWADAK-LNRIEVC 1528 Query: 537 T--GLDRQPVVEQMANMMGVKAFRLGAPLGWNPCADDNGGCSHLCFNRPDDYI--CGCPL 592 G +R+PV E+ AF G L W + L ++ P Sbjct: 1529 DWYGENRKPVFEKRGMHPFGMAF-FGDKLYWTDYKTKSVQELSLSSGVSKPFVRRLSFPR 1587 Query: 593 GLELTADKKTCVEPEAFLVYSRKNIIGRLSIKNEYNDAVIPIKDL--KEVSALALYVSGS 650 GL + D T + FL++ + + + + P+ L K V L Sbjct: 1588 GLYVY-DPSTYKTAKEFLLFIDAIAVSLNILPLDDTNIWTPVSVLPGKAVQPADLDYDPV 1646 Query: 651 K--LYWSDSKTKTINRCSVNGSAVEKIVEW-LGLVEGLAIDWSGQNIYWTDTTTQRIEVS 707 + ++W+D+ T TIN ++ + + +G+ +DW G+N+YWTD+ RIEVS Sbjct: 1647 EDAIFWTDTFTGTINSYNMQTRKSMTLHRCNVERPDGIGVDWIGRNLYWTDSGKGRIEVS 1706 Query: 708 RLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELGSK-SIKRAAMDGSSVSVFME-QVG 765 RLDG++R+ +I L++P ++VL P++G M++S+ GS+ +++A MDG+S F++ ++ Sbjct: 1707 RLDGTARKVLIQDDLERPTALVLFPEEGTMFFSDCGSRPKMEKAYMDGTSRITFVDRKIT 1766 Query: 766 RVHALAIDYERRAIYWAALDPPVVEFAFLNGTGRQ-TLADNIPMPYALALFNDSVYWGDW 824 +L ID + IYW + + F NG R+ T + P+ + L + DW Sbjct: 1767 CPTSLNIDRQSERIYWLDDNRDGIWSVFFNGANREVTYFERGTFPWGITLSGLITFVSDW 1826 Query: 825 NTGQIQQ-ARKTDGSNRKSIRKDLDYISDLKLYHRAK-SMGSNQCGVDNGGCSHLCLPTP 882 G I + + +T+ ++ +++ + ++ Y++++ + +QC +NGGCS LCL P Sbjct: 1827 KRGNIYKLSIETNVELNITVAEEIKKPTAIRYYNQSRYNFVESQCSQNNGGCSDLCLLRP 1886 Query: 883 GDVRTDYRCACPAHYRLNKDNITCSEP-------EEFLLFA--QKNAVGRI--MVANGEC 931 RT CAC L+ D TC E +LL + Q V ++ +++ C Sbjct: 1887 HS-RT---CACATGVPLSPDEKTCDHAVFNGQSNERYLLISDLQYRDVFKVPLHISDFPC 1942 Query: 932 NDAY-IPLTGLKN----VRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXX 986 Y P T L ++ Y+P ++ +YW D+ RR + Sbjct: 1943 LSLYNNPRTDLPEQSPVAASVVYNPRDRLIYWTDE-----RRGAVMRASLDDSFREVIAD 1997 Query: 987 XGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKR 1046 G+ P + +D + +YWT R I S+D + P + + Sbjct: 1998 KGIISPDGIDVDYISGNVYWTDPKRGRIEVASLDGKDRL-TLTGWSPDKPGAIVLDPVEG 2056 Query: 1047 YLIWNDVGRG-AIMRANVDGTGRVEL--ARADNATALALDQSAGTVYW 1091 + W D G IM A++DG+ R L + T LA+D +YW Sbjct: 2057 RMYWADYGTNPKIMTAHMDGSNRKILMGVGINITTGLAIDFRFRRLYW 2104 Score = 160 bits (389), Expect = 5e-39 Identities = 117/460 (25%), Positives = 217/460 (47%), Gaps = 18/460 (3%) Query: 17 LEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIAIDWYTD 76 + + T + + + ++ I W D I N T E+F + + V P +A+DW Sbjct: 1371 VNETTDITYDHFEDRIYWIDGAQRNIHRAYMNMT-EHEQFGMYT---VRPESLALDWLGR 1426 Query: 77 KLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIPKIERAG 136 LYWTD T +IE + + + + +D R + + P +G MFWTDWG PKIE++ Sbjct: 1427 HLYWTDAGTKRIEAAQLDTGIQAPVIMAGLDKPRGLVLDPPNGHMFWTDWGSKPKIEKSN 1486 Query: 137 MNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVVKGGLV 196 M+G +R ++ ++ WPN +T+DY + ++W DAKL ++V D+ GE RK V + + Sbjct: 1487 MDG--TSRWTLLDKDLIWPNALTIDYQSKRLFWADAKLNRIEVCDWYGENRKPVFEKRGM 1544 Query: 197 YPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIKVYDESRQIISAE 256 +PF + F DKLYWTD++ S+ +++ + K ++ P + VYD S +A+ Sbjct: 1545 HPFGMAFFGDKLYWTDYKTKSVQ--ELSLSSGVSKPFVRRLSFPRGLYVYDPS-TYKTAK 1601 Query: 257 DYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRE--NSSTTCYDSPQMLLVVAQRSTI 314 ++ + S L +L D N P V + + YD + + T Sbjct: 1602 EFLLFIDAIAVS-LNILPLDDT--NIWTPVSVLPGKAVQPADLDYDPVEDAIFWTDTFTG 1658 Query: 315 SKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQSVVVR 374 + S + TL +++R + D +YW D I +RLDG+ + V+++ Sbjct: 1659 TINSYNMQTRKSMTLHRCNVERPDGIGVDWIGRNLYWTDSGKGRIEVSRLDGTARKVLIQ 1718 Query: 375 SS-GVPDSIAIDPLSRKIYWTD-PVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAG 432 P ++ + P ++++D + A +DG+ + ++ P ++ + + Sbjct: 1719 DDLERPTALVLFPEEGTMFFSDCGSRPKMEKAYMDGTSRITFVDRKITCPTSLNIDRQSE 1778 Query: 433 WMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIAL 472 ++W D + + I +G+ R + E+ T+P I L Sbjct: 1779 RIYWLD--DNRDGIWSVFFNGANREVTYFERGTFPWGITL 1816 Score = 156 bits (379), Expect = 9e-38 Identities = 81/202 (40%), Positives = 117/202 (57%), Gaps = 2/202 (0%) Query: 312 STISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSD-QS 370 S S I+ P+ T T + +L + +D D + IYW+D K I +A++DG+ + Sbjct: 1015 SNASNINKLEPNSTTITPVIFNLDSAVALDVDVRDRRIYWSDTRTKAIKRAQIDGTFIED 1074 Query: 371 VVVRSSGVPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLT 430 ++ + GV D +AI+ +R+IYWTD I VA LDGS V+I + L PR IA+H Sbjct: 1075 IITTNIGVCDGLAIEWRTRRIYWTDRTYRFIQVATLDGSRRHVLISSGLDKPRGIAVHPQ 1134 Query: 431 AGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIE 490 AG MFW+DW E PKIERA LDG R +++ + WPNSIA+D N+L+W DA +E Sbjct: 1135 AGLMFWTDWGE-NPKIERARLDGQKRQEIVTSNIGWPNSIAVDYAANRLFWVDAIRDSLE 1193 Query: 491 VCNMDGTERKELHSNDIIHIFG 512 ++DG R+ L + FG Sbjct: 1194 SSDLDGRARRTLFRQPGLQPFG 1215 Score = 148 bits (359), Expect = 2e-35 Identities = 79/241 (32%), Positives = 132/241 (54%), Gaps = 6/241 (2%) Query: 607 EAFLVYSRKNIIGRLSIKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCS 666 E F+ +S + I +L + VI +L AL + V ++YWSD++TK I R Sbjct: 1009 ETFIFFSNASNINKLEPNSTTITPVI--FNLDSAVALDVDVRDRRIYWSDTRTKAIKRAQ 1066 Query: 667 VNGSAVEKIVEW-LGLVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKP 725 ++G+ +E I+ +G+ +GLAI+W + IYWTD T + I+V+ LDGS R +I GL KP Sbjct: 1067 IDGTFIEDIITTNIGVCDGLAIEWRTRRIYWTDRTYRFIQVATLDGSRRHVLISSGLDKP 1126 Query: 726 KSIVLDPKKGYMYWSELG-SKSIKRAAMDGSS-VSVFMEQVGRVHALAIDYERRAIYWAA 783 + I + P+ G M+W++ G + I+RA +DG + +G +++A+DY ++W Sbjct: 1127 RGIAVHPQAGLMFWTDWGENPKIERARLDGQKRQEIVTSNIGWPNSIAVDYAANRLFWVD 1186 Query: 784 LDPPVVEFAFLNGTGRQTLADNIPM-PYALALFNDSVYWGDWNTGQIQQARKTDGSNRKS 842 +E + L+G R+TL + P+ +++ VYW DW + I R G KS Sbjct: 1187 AIRDSLESSDLDGRARRTLFRQPGLQPFGVSILGKHVYWSDWASEGIHMNRMGTGKLEKS 1246 Query: 843 I 843 + Sbjct: 1247 V 1247 Score = 122 bits (295), Expect = 1e-27 Identities = 80/299 (26%), Positives = 145/299 (48%), Gaps = 18/299 (6%) Query: 11 TTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIA 70 T + + +V ++ R LI W+D++ + + ++++ + I +G+++P GI Sbjct: 1951 TDLPEQSPVAASVVYNPRDRLIYWTDERRGAVMRASLDDSF---REVIADKGIISPDGID 2007 Query: 71 IDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIP 130 +D+ + +YWTD + +IEV S+ K R L D AI + P +G M+W D+G P Sbjct: 2008 VDYISGNVYWTDPKRGRIEVASLDGKDRLTLTGWSPDKPGAIVLDPVEGRMYWADYGTNP 2067 Query: 131 KIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRV 190 KI A M+G + RK+++ I G+ +D+ +YW D ++ + NG R V Sbjct: 2068 KIMTAHMDG--SNRKILMGVGINITTGLAIDFRFRRLYWCDMGTGKIESMSLNGGNRISV 2125 Query: 191 --VKGGLVY---PFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIKV 245 + G + PF L FS KLYW D ++Y ++A ++ + P D++V Sbjct: 2126 YDLNAGRKFRARPFGLAFSKGKLYWADMMAGTVYELEVATGTTRV--VASGLFSPTDVRV 2183 Query: 246 YDESRQIISAEDYPCKK-NNAGCSHLCLLSPDPPGYNC--ACPTGVKLRENSSTTCYDS 301 D+ R++ Y C K + L + PG C +C G ++ ++ CY++ Sbjct: 2184 VDQ-RELFDV--YRCSKPPRTRHRKVDPLCNNLPGTRCTFSCEPGYAMQGQATLHCYNN 2239 Score = 66.5 bits (155), Expect = 1e-10 Identities = 46/150 (30%), Positives = 67/150 (44%), Gaps = 12/150 (8%) Query: 947 IEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVLGRTMYW 1006 I YD E ++YW+D +I R ++ RP + LD LGR +YW Sbjct: 1377 ITYDHFEDRIYWIDGAQRNIHRAYMNMTEHEQFGMYTV------RPESLALDWLGRHLYW 1430 Query: 1007 TCADRDSINATSIDNNSSTGVIVRG-DRMLPRHLAFHQTKRYLIWNDVG-RGAIMRANVD 1064 T A I A +D VI+ G D+ PR L ++ W D G + I ++N+D Sbjct: 1431 TDAGTKRIEAAQLDTGIQAPVIMAGLDK--PRGLVLDPPNGHMFWTDWGSKPKIEKSNMD 1488 Query: 1065 GTGRVELARADN--ATALALDQSAGTVYWA 1092 GT R L D AL +D + ++WA Sbjct: 1489 GTSRWTLLDKDLIWPNALTIDYQSKRLFWA 1518 Score = 64.9 bits (151), Expect = 4e-10 Identities = 48/212 (22%), Positives = 101/212 (47%), Gaps = 6/212 (2%) Query: 637 LKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEWLGLVEGLAIDWSGQNIYW 696 L ++ L L S + + S IN+ N + + ++ L L +D + IYW Sbjct: 995 LLKLRILLLRSSRGETFIFFSNASNINKLEPNSTTITPVIFNLDSAVALDVDVRDRRIYW 1054 Query: 697 TDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELGSKSIKRAAMDGSS 756 +DT T+ I+ +++DG+ II + + ++ + +YW++ + I+ A +DGS Sbjct: 1055 SDTRTKAIKRAQIDGTFIEDIITTNIGVCDGLAIEWRTRRIYWTDRTYRFIQVATLDGSR 1114 Query: 757 VSVFMEQ-VGRVHALAIDYERRAIYWAAL-DPPVVEFAFLNGTGRQTL-ADNIPMPYALA 813 V + + + +A+ + ++W + P +E A L+G RQ + NI P ++A Sbjct: 1115 RHVLISSGLDKPRGIAVHPQAGLMFWTDWGENPKIERARLDGQKRQEIVTSNIGWPNSIA 1174 Query: 814 L--FNDSVYWGDWNTGQIQQARKTDGSNRKSI 843 + + ++W D ++ + DG R+++ Sbjct: 1175 VDYAANRLFWVDAIRDSLESS-DLDGRARRTL 1205 Score = 50.0 bits (114), Expect = 1e-05 Identities = 45/206 (21%), Positives = 86/206 (41%), Gaps = 16/206 (7%) Query: 907 SEPEEFLLFAQKNAVGRIMVANGECNDAYIP--LTGLKNVRAIEYDPVEKQLYWMDDDSH 964 S E F+ F+ + + ++ E N I + L + A++ D ++++YW D + Sbjct: 1006 SRGETFIFFSNASNINKL-----EPNSTTITPVIFNLDSAVALDVDVRDRRIYWSDTRTK 1060 Query: 965 SIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSS 1024 +I+R I + + ++ R +YWT I ++D S Sbjct: 1061 AIKRAQID-----GTFIEDIITTNIGVCDGLAIEWRTRRIYWTDRTYRFIQVATLD-GSR 1114 Query: 1025 TGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRG-AIMRANVDGTGRVELARADNA--TALA 1081 V++ PR +A H + W D G I RA +DG R E+ ++ ++A Sbjct: 1115 RHVLISSGLDKPRGIAVHPQAGLMFWTDWGENPKIERARLDGQKRQEIVTSNIGWPNSIA 1174 Query: 1082 LDQSAGTVYWAVSRQCDGQQDCEDGR 1107 +D +A ++W + + + DGR Sbjct: 1175 VDYAANRLFWVDAIRDSLESSDLDGR 1200 Score = 42.3 bits (95), Expect = 0.002 Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 5/91 (5%) Query: 3 NTSRLTRITTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEG 62 N +R T + KDL A+ Y+ + W+D K I+ ++ Y + + + Sbjct: 1486 NMDGTSRWTLLDKDLIWPNALTIDYQSKRLFWADAKLNRIEVCDW---YGENRKPVFEKR 1542 Query: 63 LVTPTGIAIDWYTDKLYWTDGETNKIEVISI 93 + P G+A ++ DKLYWTD +T ++ +S+ Sbjct: 1543 GMHPFGMA--FFGDKLYWTDYKTKSVQELSL 1571 Score = 38.7 bits (86), Expect = 0.028 Identities = 43/192 (22%), Positives = 75/192 (39%), Gaps = 15/192 (7%) Query: 909 PEEFLLFAQKNAVGRIMVANGECNDAY---IPLTGLKNVRAIEYDPVEKQLYWMDDDSHS 965 P + L++ G +M A+ +D++ I G+ + I+ D + +YW D Sbjct: 1967 PRDRLIYWTDERRGAVMRAS--LDDSFREVIADKGIISPDGIDVDYISGNVYWTDP---- 2020 Query: 966 IRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSST 1025 +R I +P +VLD + MYW + T+ + S+ Sbjct: 2021 -KRGRIEVASLDGKDRLTLTGWSPDKPGAIVLDPVEGRMYWADYGTNPKIMTAHMDGSNR 2079 Query: 1026 GVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGAIMRANVDGTGRVEL-----ARADNATAL 1080 +++ + LA R L W D+G G I +++G R+ + R A Sbjct: 2080 KILMGVGINITTGLAIDFRFRRLYWCDMGTGKIESMSLNGGNRISVYDLNAGRKFRARPF 2139 Query: 1081 ALDQSAGTVYWA 1092 L S G +YWA Sbjct: 2140 GLAFSKGKLYWA 2151 Score = 33.1 bits (72), Expect = 1.4 Identities = 24/106 (22%), Positives = 39/106 (36%), Gaps = 2/106 (1%) Query: 988 GLSRPYHMVLDVLGRTMYWT-CADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKR 1046 GL +P + + M+WT + I +D IV + P +A Sbjct: 1122 GLDKPRGIAVHPQAGLMFWTDWGENPKIERARLDGQKRQE-IVTSNIGWPNSIAVDYAAN 1180 Query: 1047 YLIWNDVGRGAIMRANVDGTGRVELARADNATALALDQSAGTVYWA 1092 L W D R ++ +++DG R L R + VYW+ Sbjct: 1181 RLFWVDAIRDSLESSDLDGRARRTLFRQPGLQPFGVSILGKHVYWS 1226 >SB_4238| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1288 Score = 232 bits (567), Expect = 1e-60 Identities = 118/286 (41%), Positives = 156/286 (54%), Gaps = 5/286 (1%) Query: 11 TTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIA 70 T + L A+D+ + +I WSD I+ N E IV+ L+TP GIA Sbjct: 934 TQVVPKLRAAIALDYDFATGVIYWSDVIEASIKSAPLNNGSAVET--IVNMSLLTPDGIA 991 Query: 71 IDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIP 130 +DW KLYWTD T+ IEV ++ + R L + + RAI V P G MFWTDWGE P Sbjct: 992 VDWVNRKLYWTDTGTDVIEVANLDGRERMRLITTGLQEPRAIVVYPAIGYMFWTDWGEEP 1051 Query: 131 KIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRV 190 KIER GMNGDP TR IV NI WPN +T+DY I+W DAK ++ + +G R+ + Sbjct: 1052 KIERCGMNGDPKTRLQIVNTNILWPNALTIDYTIDKIWWADAKEHTIECANLDGTARRVI 1111 Query: 191 VKGGLVYPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIKVYDESR 250 + +PFA+T D +YWTDW SIY + NG + P DI VY + + Sbjct: 1112 TSDSVHHPFAITVFQDYIYWTDWVKESIYKAN-KFNGKDRSLVCSGLYSPMDIHVYQQQK 1170 Query: 251 QIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSST 296 Q PC +NN GCSH CLL+P P + C CP + L E+S+T Sbjct: 1171 Q--PKFSNPCGENNGGCSHTCLLAPLPKSHTCHCPPNINLLEDSAT 1214 Score = 222 bits (543), Expect = 1e-57 Identities = 125/345 (36%), Positives = 189/345 (54%), Gaps = 14/345 (4%) Query: 573 GGCSHLCFNRPDDYICGCPLGLELTADKKTC--VEPEAFLVYSRKNIIGRLSIKNEYNDA 630 G CS +CFN Y C C G L DKKTC + + FL+++ + I RL + + Sbjct: 876 GSCSQMCFNSKGSYKCTCMEGYRLEPDKKTCKALGDKPFLLFTNRQDIRRLVMDSSDFTQ 935 Query: 631 VIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVN-GSAVEKIVEWLGLV-EGLAID 688 V+P L+ AL + +YWSD +I +N GSAVE IV L +G+A+D Sbjct: 936 VVP--KLRAAIALDYDFATGVIYWSDVIEASIKSAPLNNGSAVETIVNMSLLTPDGIAVD 993 Query: 689 WSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELGSK-SI 747 W + +YWTDT T IEV+ LDG R +I GL++P++IV+ P GYM+W++ G + I Sbjct: 994 WVNRKLYWTDTGTDVIEVANLDGRERMRLITTGLQEPRAIVVYPAIGYMFWTDWGEEPKI 1053 Query: 748 KRAAMDG---SSVSVFMEQVGRVHALAIDYERRAIYWAALDPPVVEFAFLNGTGRQTL-A 803 +R M+G + + + + +AL IDY I+WA +E A L+GT R+ + + Sbjct: 1054 ERCGMNGDPKTRLQIVNTNILWPNALTIDYTIDKIWWADAKEHTIECANLDGTARRVITS 1113 Query: 804 DNIPMPYALALFNDSVYWGDWNTGQIQQARKTDGSNRKSIRKDLDYISDLKLYHRAKS-M 862 D++ P+A+ +F D +YW DW I +A K +G +R + L D+ +Y + K Sbjct: 1114 DSVHHPFAITVFQDYIYWTDWVKESIYKANKFNGKDRSLVCSGLYSPMDIHVYQQQKQPK 1173 Query: 863 GSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCS 907 SN CG +NGGCSH CL P + + C CP + L +D+ TC+ Sbjct: 1174 FSNPCGENNGGCSHTCLLAP--LPKSHTCHCPPNINLLEDSATCN 1216 Score = 219 bits (535), Expect = 1e-56 Identities = 116/344 (33%), Positives = 178/344 (51%), Gaps = 13/344 (3%) Query: 267 CSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQMLLVVAQRSTISKISLDSPDFTP 326 CS +C S Y C C G +L + T + L+ R I ++ +DS DFT Sbjct: 878 CSQMCFNSKG--SYKCTCMEGYRLEPDKKTCKALGDKPFLLFTNRQDIRRLVMDSSDFTQ 935 Query: 327 YTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSD--QSVVVRSSGVPDSIAI 384 + L+ + +D+D T IYW+D + +I A L+ +++V S PD IA+ Sbjct: 936 V---VPKLRAAIALDYDFATGVIYWSDVIEASIKSAPLNNGSAVETIVNMSLLTPDGIAV 992 Query: 385 DPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKP 444 D ++RK+YWTD D I VA LDG +I T L +PRAI ++ G+MFW+DW E +P Sbjct: 993 DWVNRKLYWTDTGTDVIEVANLDGRERMRLITTGLQEPRAIVVYPAIGYMFWTDWGE-EP 1051 Query: 445 KIERANLDG--SGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERKEL 502 KIER ++G R+ +++ + WPN++ +D +K++W DA+ H IE N+DGT R+ + Sbjct: 1052 KIERCGMNGDPKTRLQIVNTNILWPNALTIDYTIDKIWWADAKEHTIECANLDGTARRVI 1111 Query: 503 HSNDIIHIFGXXXXXXXXXXXXMQKRTLDRINKNTGLDRQPVVEQMANMMGVKAF-RLGA 561 S+ + H F K ++ + NK G DR V + + M + + + Sbjct: 1112 TSDSVHHPFAITVFQDYIYWTDWVKESIYKANKFNGKDRSLVCSGLYSPMDIHVYQQQKQ 1171 Query: 562 PLGWNPCADDNGGCSHLCF--NRPDDYICGCPLGLELTADKKTC 603 P NPC ++NGGCSH C P + C CP + L D TC Sbjct: 1172 PKFSNPCGENNGGCSHTCLLAPLPKSHTCHCPPNINLLEDSATC 1215 Score = 80.6 bits (190), Expect = 7e-15 Identities = 58/239 (24%), Positives = 101/239 (42%), Gaps = 20/239 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSE--PEEFLLFAQKNAVG 922 ++C + G CS +C + G Y+C C YRL D TC + FLLF + + Sbjct: 870 DECAIP-GSCSQMCFNSKGS----YKCTCMEGYRLEPDKKTCKALGDKPFLLFTNRQDIR 924 Query: 923 RIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXX 982 R+++ + + +P L+ A++YD +YW D SI+ P++ Sbjct: 925 RLVMDSSDFTQV-VPK--LRAAIALDYDFATGVIYWSDVIEASIKSAPLN----NGSAVE 977 Query: 983 XXXXXGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFH 1042 L P + +D + R +YWT D I ++D +I G PR + + Sbjct: 978 TIVNMSLLTPDGIAVDWVNRKLYWTDTGTDVIEVANLDGRERMRLITTG-LQEPRAIVVY 1036 Query: 1043 QTKRYLIWNDVG-RGAIMRANVDGTGRVELARADN----ATALALDQSAGTVYWAVSRQ 1096 Y+ W D G I R ++G + L + AL +D + ++WA +++ Sbjct: 1037 PAIGYMFWTDWGEEPKIERCGMNGDPKTRLQIVNTNILWPNALTIDYTIDKIWWADAKE 1095 Score = 78.6 bits (185), Expect = 3e-14 Identities = 69/247 (27%), Positives = 108/247 (43%), Gaps = 14/247 (5%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQMLL--VVAQRSTISKI 317 CK NN C H C + GY C+C G K+ + +C D + + +Q SK Sbjct: 830 CKDNNGPCQHYC--NDTKTGYFCSCRPGYKVALDDPKSCRDVDECAIPGSCSQMCFNSKG 887 Query: 318 SLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQSVVVRSSG 377 S Y L D K + P ++ + + + I + +D SD + VV Sbjct: 888 SYKCTCMEGYRLE-PDKKTCKALGDKP---FLLFTN--RQDIRRLVMDSSDFTQVVPKLR 941 Query: 378 VPDSIAIDPLSRKIYWTDPVMDTINVARL-DGSYEKVIIHTELYDPRAIALHLTAGWMFW 436 ++ D + IYW+D + +I A L +GS + I++ L P IA+ ++W Sbjct: 942 AAIALDYDFATGVIYWSDVIEASIKSAPLNNGSAVETIVNMSLLTPDGIAVDWVNRKLYW 1001 Query: 437 SDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGD-ARTHKIEVCNMD 495 +D IE ANLDG R+ LI+ L P +I + ++W D KIE C M+ Sbjct: 1002 TDTG--TDVIEVANLDGRERMRLITTGLQEPRAIVVYPAIGYMFWTDWGEEPKIERCGMN 1059 Query: 496 GTERKEL 502 G + L Sbjct: 1060 GDPKTRL 1066 Score = 76.2 bits (179), Expect = 1e-13 Identities = 74/293 (25%), Positives = 124/293 (42%), Gaps = 18/293 (6%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTA-DKKTCVEPEAFLV---YSRKNIIGRL 621 N C D+NG C H C + Y C C G ++ D K+C + + + S+ + Sbjct: 828 NECKDNNGPCQHYCNDTKTGYFCSCRPGYKVALDDPKSCRDVDECAIPGSCSQMCFNSKG 887 Query: 622 SIKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEWLGL 681 S K + D K AL G K + + + I R ++ S ++V L Sbjct: 888 SYKCTCMEGYRLEPDKKTCKAL-----GDKPFLLFTNRQDIRRLVMDSSDFTQVVPKLRA 942 Query: 682 VEGLAIDWSGQNIYWTDTTTQRIEVSRL-DGSSRRAIIWQGLKKPKSIVLDPKKGYMYWS 740 L D++ IYW+D I+ + L +GS+ I+ L P I +D +YW+ Sbjct: 943 AIALDYDFATGVIYWSDVIEASIKSAPLNNGSAVETIVNMSLLTPDGIAVDWVNRKLYWT 1002 Query: 741 ELGSKSIKRAAMDG-SSVSVFMEQVGRVHALAIDYERRAIYWAAL-DPPVVEFAFLNG-- 796 + G+ I+ A +DG + + + A+ + ++W + P +E +NG Sbjct: 1003 DTGTDVIEVANLDGRERMRLITTGLQEPRAIVVYPAIGYMFWTDWGEEPKIERCGMNGDP 1062 Query: 797 -TGRQTLADNIPMPYALAL--FNDSVYWGDWNTGQIQQARKTDGSNRKSIRKD 846 T Q + NI P AL + D ++W D I+ A DG+ R+ I D Sbjct: 1063 KTRLQIVNTNILWPNALTIDYTIDKIWWADAKEHTIECA-NLDGTARRVITSD 1114 Score = 55.2 bits (127), Expect = 3e-07 Identities = 52/232 (22%), Positives = 90/232 (38%), Gaps = 20/232 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDN-ITCSEPEEFLLFAQKNAVGR 923 N+C +NG C H C D +T Y C+C Y++ D+ +C + +E + + + Sbjct: 828 NECKDNNGPCQHYC----NDTKTGYFCSCRPGYKVALDDPKSCRDVDECAIPGSCSQMCF 883 Query: 924 IMVANGECN--DAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXX 981 + +C + Y K +A+ P + + + IRR+ + Sbjct: 884 NSKGSYKCTCMEGYRLEPDKKTCKALGDKP-----FLLFTNRQDIRRLVMDSSDFTQVVP 938 Query: 982 XXXXXXGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAF 1041 L Y V+ YW+ SI + ++N S+ IV + P +A Sbjct: 939 KLRAAIALD--YDFATGVI----YWSDVIEASIKSAPLNNGSAVETIVNMSLLTPDGIAV 992 Query: 1042 HQTKRYLIWNDVGRGAIMRANVDGTGRVELARA--DNATALALDQSAGTVYW 1091 R L W D G I AN+DG R+ L A+ + + G ++W Sbjct: 993 DWVNRKLYWTDTGTDVIEVANLDGRERMRLITTGLQEPRAIVVYPAIGYMFW 1044 Score = 46.0 bits (104), Expect = 2e-04 Identities = 30/106 (28%), Positives = 39/106 (36%), Gaps = 18/106 (16%) Query: 1092 AVSRQCDGQQDCEDGRDEAEC--GACGGDV--RCADGT-----------XXXXXXXXXXX 1136 A + +CDG+ DC D DE C C D RC +G Sbjct: 601 AATWKCDGEDDCGDNSDEINCPKATCNPDTQFRCTNGRCIPRRWVCDKDDDCHDGSDERN 660 Query: 1137 XXXXXXXXXDAFRCDEGLCIAARFVCDGRPQCADGSDE---APAAC 1179 + C G+C+ R+VCD C DG+DE AP C Sbjct: 661 SCATMTCSENEITCGNGICVVKRWVCDQDDDCGDGTDELNCAPHTC 706 Score = 39.9 bits (89), Expect = 0.012 Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 4/47 (8%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE----APAACAYGHTDQVNGI 1190 FRC G CI R+VCD C DGSDE A C+ NGI Sbjct: 632 FRCTNGRCIPRRWVCDKDDDCHDGSDERNSCATMTCSENEITCGNGI 678 Score = 36.3 bits (80), Expect = 0.15 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query: 2 VNTSRLTRITTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSE 61 +N TR+ + ++ A+ Y + I W+D K I+C N + T + I S+ Sbjct: 1058 MNGDPKTRLQIVNTNILWPNALTIDYTIDKIWWADAKEHTIECANLDGT---ARRVITSD 1114 Query: 62 GLVTPTGIAIDWYTDKLYWTD 82 + P I + + D +YWTD Sbjct: 1115 SVHHPFAITV--FQDYIYWTD 1133 Score = 35.5 bits (78), Expect = 0.26 Identities = 37/166 (22%), Positives = 60/166 (36%), Gaps = 8/166 (4%) Query: 928 NGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXX 987 NG + + ++ L I D V ++LYW D + I + Sbjct: 972 NGSAVETIVNMS-LLTPDGIAVDWVNRKLYWTDTGTDVIEVANLD-----GRERMRLITT 1025 Query: 988 GLSRPYHMVLDVLGRTMYWT-CADRDSINATSIDNNSSTGV-IVRGDRMLPRHLAFHQTK 1045 GL P +V+ M+WT + I ++ + T + IV + + P L T Sbjct: 1026 GLQEPRAIVVYPAIGYMFWTDWGEEPKIERCGMNGDPKTRLQIVNTNILWPNALTIDYTI 1085 Query: 1046 RYLIWNDVGRGAIMRANVDGTGRVELARADNATALALDQSAGTVYW 1091 + W D I AN+DGT R + A+ +YW Sbjct: 1086 DKIWWADAKEHTIECANLDGTARRVITSDSVHHPFAITVFQDYIYW 1131 Score = 35.1 bits (77), Expect = 0.34 Identities = 14/27 (51%), Positives = 17/27 (62%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 F C + CI +R+ CDG CAD SDE Sbjct: 711 FTCADKRCILSRWRCDGDRDCADNSDE 737 Score = 34.3 bits (75), Expect = 0.60 Identities = 27/93 (29%), Positives = 32/93 (34%), Gaps = 15/93 (16%) Query: 1097 CDGQQDCEDGRDEAECG--ACG------GDVRC------ADGTXXXXXXXXXXXXXXXXX 1142 CD DC DG DE C C D RC DG Sbjct: 686 CDQDDDCGDGTDELNCAPHTCRPNEFTCADKRCILSRWRCDGDRDCADNSDEINCPNSSQ 745 Query: 1143 XXXDA-FRCDEGLCIAARFVCDGRPQCADGSDE 1174 + ++C G CI +VCDG C + SDE Sbjct: 746 YCKSSEYQCSTGECIHKSWVCDGEFDCLNKSDE 778 Score = 31.9 bits (69), Expect = 3.2 Identities = 12/20 (60%), Positives = 13/20 (65%) Query: 1155 CIAARFVCDGRPQCADGSDE 1174 CIAA + CDG C D SDE Sbjct: 599 CIAATWKCDGEDDCGDNSDE 618 >SB_16934| Best HMM Match : Ldl_recept_b (HMM E-Value=1.7e-39) Length = 407 Score = 184 bits (447), Expect = 5e-46 Identities = 110/344 (31%), Positives = 172/344 (50%), Gaps = 15/344 (4%) Query: 272 LLSPDPPGYNCACPTGVKLRENSST-TCYDSPQMLLVVAQRSTISKISLDSPDFTPYTLP 330 L + P G C +KL T + D + ++ + I I+LD T Y Sbjct: 28 LFAITPAGERGMCCKAIKLVFVVCTGSSIDLNRPFIIFSNTVDIRHINLDG---TGYGYI 84 Query: 331 LKDLKRTLTVDFDPKTEYIYWADGLAKTISKARL-DGSDQS----VVVRSSGVPDSIAID 385 ++ L + +DFD K+ YIYW+D K I + + G D S V+ + G+P+ +A+D Sbjct: 85 VRGLINVVGLDFDVKSGYIYWSDVTTKKIQRVHIHQGLDSSKIEDFVMSNLGIPEDLALD 144 Query: 386 PLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKPK 445 R+++WTDP + TI+V LDG+ + +I T PRA+ + ++W++W + + Sbjct: 145 WKGRRLFWTDPGLGTISVIGLDGTGRRALIGTS-GKPRAVLVDPLDDKLYWTEWGQDA-R 202 Query: 446 IERANL-DGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERKEL-H 503 I RA L DGSG+ +L+S L WPN +A+D V+ K+YW DA T +E C++DG R L Sbjct: 203 ITRARLSDGSGKEVLVSTGLVWPNGLAMDYVDKKIYWADASTDMVEKCDLDGENRLTLID 262 Query: 504 SNDIIHIFGXXXXXXXXXXXXMQKRTLDRINKNTGLDRQPVVEQMANMMGVKAFRLGAPL 563 + H + Q+ T++ +K +G R + M + + Sbjct: 263 HTKVYHPYSLTLFRDRLYWTDWQQHTIEHCDKLSGGGRVSLSGGMTRPSALHVYHPERQP 322 Query: 564 GWNP--CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 G P C +NGGCSH C N Y C CP G EL+ DK+TC + Sbjct: 323 GAGPNECLVNNGGCSHTCLNLIGGYSCLCPPGFELSLDKRTCTD 366 Score = 181 bits (440), Expect = 4e-45 Identities = 107/290 (36%), Positives = 149/290 (51%), Gaps = 17/290 (5%) Query: 634 IKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVN----GSAVEKIV-EWLGLVEGLAID 688 ++ L V L V +YWSD TK I R ++ S +E V LG+ E LA+D Sbjct: 85 VRGLINVVGLDFDVKSGYIYWSDVTTKKIQRVHIHQGLDSSKIEDFVMSNLGIPEDLALD 144 Query: 689 WSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELGSKS-I 747 W G+ ++WTD I V LDG+ RRA+I KP+++++DP +YW+E G + I Sbjct: 145 WKGRRLFWTDPGLGTISVIGLDGTGRRALIGTS-GKPRAVLVDPLDDKLYWTEWGQDARI 203 Query: 748 KRAAMDGSSVSVFMEQVGRV--HALAIDYERRAIYWAALDPPVVEFAFLNGTGRQTLADN 805 RA + S + G V + LA+DY + IYWA +VE L+G R TL D+ Sbjct: 204 TRARLSDGSGKEVLVSTGLVWPNGLAMDYVDKKIYWADASTDMVEKCDLDGENRLTLIDH 263 Query: 806 IPM--PYALALFNDSVYWGDWNTGQIQQARKTDGSNRKSIRKDLDYISDLKLYH--RAKS 861 + PY+L LF D +YW DW I+ K G R S+ + S L +YH R Sbjct: 264 TKVYHPYSLTLFRDRLYWTDWQQHTIEHCDKLSGGGRVSLSGGMTRPSALHVYHPERQPG 323 Query: 862 MGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 G N+C V+NGGCSH CL G Y C CP + L+ D TC++ E Sbjct: 324 AGPNECLVNNGGCSHTCLNLIG----GYSCLCPPGFELSLDKRTCTDINE 369 Score = 171 bits (416), Expect = 3e-42 Identities = 99/290 (34%), Positives = 146/290 (50%), Gaps = 9/290 (3%) Query: 13 IAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFK-IVSEGLVTPTGIAI 71 I + L +DF + I WSD + IQ ++ ++ K + V L P +A+ Sbjct: 84 IVRGLINVVGLDFDVKSGYIYWSDVTTKKIQRVHIHQGLDSSKIEDFVMSNLGIPEDLAL 143 Query: 72 DWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIPK 131 DW +L+WTD I VI + R+ L + RA+ V P D ++WT+WG+ + Sbjct: 144 DWKGRRLFWTDPGLGTISVIGLDGTGRRALIGTS-GKPRAVLVDPLDDKLYWTEWGQDAR 202 Query: 132 IERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVV 191 I RA ++ D + ++V+V + WPNG+ +DY + IYW DA V+ D +GE R ++ Sbjct: 203 ITRARLS-DGSGKEVLVSTGLVWPNGLAMDYVDKKIYWADASTDMVEKCDLDGENRLTLI 261 Query: 192 KGGLVY-PFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIKVYDESR 250 VY P++LT D+LYWTDWQ +I D + G ++ L P+ + VY R Sbjct: 262 DHTKVYHPYSLTLFRDRLYWTDWQQHTIEHCDKLSGGGRV-SLSGGMTRPSALHVYHPER 320 Query: 251 QIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYD 300 Q A C NN GCSH CL GY+C CP G +L TC D Sbjct: 321 Q-PGAGPNECLVNNGGCSHTCLNLIG--GYSCLCPPGFEL-SLDKRTCTD 366 Score = 89.4 bits (212), Expect = 2e-17 Identities = 67/273 (24%), Positives = 119/273 (43%), Gaps = 17/273 (6%) Query: 643 LALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEWLGLVEGLAIDWSGQNIYWTDTTTQ 702 LAL G +L+W+D TI+ ++G+ ++ G + +D +YWT+ Sbjct: 141 LALDWKGRRLFWTDPGLGTISVIGLDGTGRRALIGTSGKPRAVLVDPLDDKLYWTEWGQD 200 Query: 703 -RIEVSRL-DGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELGSKSIKRAAMDGSSVSVF 760 RI +RL DGS + ++ GL P + +D +YW++ + +++ +DG + Sbjct: 201 ARITRARLSDGSGKEVLVSTGLVWPNGLAMDYVDKKIYWADASTDMVEKCDLDGENRLTL 260 Query: 761 MEQVGRVHALAIDYERRAIYWAALDPPVVEFAF-LNGTGRQTLADNIPMPYALALFNDSV 819 ++ H ++ R +YW +E L+G GR +L+ + P AL +++ Sbjct: 261 IDHTKVYHPYSLTLFRDRLYWTDWQQHTIEHCDKLSGGGRVSLSGGMTRPSALHVYHPER 320 Query: 820 YWGDWNTGQIQQARKTDGSNRKSIRKDLDYIS------DLKLYHRAKSMGSNQCGVDNGG 873 G G + G + + Y +L L R + N+CG + GG Sbjct: 321 QPG---AGPNECLVNNGGCSHTCLNLIGGYSCLCPPGFELSLDKRTCT-DINECGYNRGG 376 Query: 874 CSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 C +C + G Y C+C Y LN+D TC Sbjct: 377 CGQICTNSLG----SYNCSCLNGYVLNEDLRTC 405 Score = 76.6 bits (180), Expect = 1e-13 Identities = 57/210 (27%), Positives = 95/210 (45%), Gaps = 16/210 (7%) Query: 657 SKTKTINRCSVNGSAVEKIVEWLGLVEGLAIDWSGQNIYWTDTTT---QRIEVSR-LDGS 712 S T I +++G+ IV L V GL D IYW+D TT QR+ + + LD S Sbjct: 66 SNTVDIRHINLDGTGYGYIVRGLINVVGLDFDVKSGYIYWSDVTTKKIQRVHIHQGLDSS 125 Query: 713 SRRAIIWQGLKKPKSIVLDPKKGYMYWSELGSKSIKRAAMDGSSVSVFMEQVGRVHALAI 772 + L P+ + LD K ++W++ G +I +DG+ + G+ A+ + Sbjct: 126 KIEDFVMSNLGIPEDLALDWKGRRLFWTDPGLGTISVIGLDGTGRRALIGTSGKPRAVLV 185 Query: 773 DYERRAIYWA--ALDPPVVEFAFLNGTGRQTL-ADNIPMPYALAL--FNDSVYWGDWNTG 827 D +YW D + +G+G++ L + + P LA+ + +YW D +T Sbjct: 186 DPLDDKLYWTEWGQDARITRARLSDGSGKEVLVSTGLVWPNGLAMDYVDKKIYWADASTD 245 Query: 828 QIQQARKTDGSNRKSIRKDLDYISDLKLYH 857 +++ DG NR L I K+YH Sbjct: 246 MVEKC-DLDGENR------LTLIDHTKVYH 268 Score = 55.2 bits (127), Expect = 3e-07 Identities = 47/174 (27%), Positives = 72/174 (41%), Gaps = 9/174 (5%) Query: 940 GLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDV 999 GL NV +++D +YW D + I+RV I + L P + LD Sbjct: 87 GLINVVGLDFDVKSGYIYWSDVTTKKIQRVHI-HQGLDSSKIEDFVMSNLGIPEDLALDW 145 Query: 1000 LGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGA-I 1058 GR ++WT +I+ +D +I G PR + L W + G+ A I Sbjct: 146 KGRRLFWTDPGLGTISVIGLDGTGRRALI--GTSGKPRAVLVDPLDDKLYWTEWGQDARI 203 Query: 1059 MRANV-DGTGRVELARADNA--TALALDQSAGTVYWAVSRQCDGQQDCE-DGRD 1108 RA + DG+G+ L LA+D +YWA D + C+ DG + Sbjct: 204 TRARLSDGSGKEVLVSTGLVWPNGLAMDYVDKKIYWA-DASTDMVEKCDLDGEN 256 Score = 52.8 bits (121), Expect = 2e-06 Identities = 44/170 (25%), Positives = 81/170 (47%), Gaps = 16/170 (9%) Query: 53 GEKFKIVSEGLVTPTGIAIDWYTDKLYWTDGETNKIEVISIVQ--KYRKV--LFWSEVDL 108 G + + GL+ G+ D + +YW+D T KI+ + I Q K+ S + + Sbjct: 78 GTGYGYIVRGLINVVGLDFDVKSGYIYWSDVTTKKIQRVHIHQGLDSSKIEDFVMSNLGI 137 Query: 109 ARAIAVVPEDGLMFWTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIY 168 +A+ + +FWTD G + I G++G R+ ++ + P + VD + +Y Sbjct: 138 PEDLALDWKGRRLFWTDPG-LGTISVIGLDG--TGRRALIGTS-GKPRAVLVDPLDDKLY 193 Query: 169 WV----DAKLQFVDVIDFNGEKRKRVVKGGLVYP--FALTFSNDKLYWTD 212 W DA++ + D G ++ +V GLV+P A+ + + K+YW D Sbjct: 194 WTEWGQDARITRARLSD--GSGKEVLVSTGLVWPNGLAMDYVDKKIYWAD 241 Score = 38.3 bits (85), Expect = 0.037 Identities = 15/38 (39%), Positives = 18/38 (47%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N C + GGC +C N Y C C G L D +TC Sbjct: 368 NECGYNRGGCGQICTNSLGSYNCSCLNGYVLNEDLRTC 405 Score = 37.5 bits (83), Expect = 0.064 Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 1/82 (1%) Query: 991 RPYHMVLDVLGRTMYWTCADRDS-INATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLI 1049 +P +++D L +YWT +D+ I + + S V+V + P LA + + Sbjct: 179 KPRAVLVDPLDDKLYWTEWGQDARITRARLSDGSGKEVLVSTGLVWPNGLAMDYVDKKIY 238 Query: 1050 WNDVGRGAIMRANVDGTGRVEL 1071 W D + + ++DG R+ L Sbjct: 239 WADASTDMVEKCDLDGENRLTL 260 >SB_44751| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 842 Score = 130 bits (315), Expect = 5e-30 Identities = 64/168 (38%), Positives = 98/168 (58%), Gaps = 2/168 (1%) Query: 329 LPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDG-SDQSVVVRSSGVPDSIAIDPL 387 LP+ + + DP + +YW+D A+ IS+A LDG +++++ VPD +A+D + Sbjct: 650 LPITQGIMVVAMAHDPVDKRVYWSDVGAQKISRAYLDGRGEETIITTDIVVPDGMALDTV 709 Query: 388 SRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKPKIE 447 R+IYWTD I A DGS+ + + L +PR I L M+W+DW P+IE Sbjct: 710 ERRIYWTDIGRKRIERAHFDGSHREELERAGLDNPRGIVLARARRQMYWTDWGAN-PRIE 768 Query: 448 RANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMD 495 RA++DG R ++S L WPN IALD ++LYW DA+ KIE +++ Sbjct: 769 RASMDGGQRKTIVSGALGWPNGIALDEPLSQLYWADAKLDKIETSDLE 816 Score = 95.5 bits (227), Expect = 2e-19 Identities = 48/124 (38%), Positives = 69/124 (55%), Gaps = 2/124 (1%) Query: 58 IVSEGLVTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPE 117 I++ +V P G+A+D ++YWTD +IE +R+ L + +D R I + Sbjct: 693 IITTDIVVPDGMALDTVERRIYWTDIGRKRIERAHFDGSHREELERAGLDNPRGIVLARA 752 Query: 118 DGLMFWTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFV 177 M+WTDWG P+IERA M+G RK IV + WPNGI +D S +YW DAKL + Sbjct: 753 RRQMYWTDWGANPRIERASMDG--GQRKTIVSGALGWPNGIALDEPLSQLYWADAKLDKI 810 Query: 178 DVID 181 + D Sbjct: 811 ETSD 814 Score = 87.4 bits (207), Expect = 6e-17 Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 3/154 (1%) Query: 632 IPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEW-LGLVEGLAIDWS 690 +PI V A+A ++YWSD + I+R ++G E I+ + + +G+A+D Sbjct: 650 LPITQGIMVVAMAHDPVDKRVYWSDVGAQKISRAYLDGRGEETIITTDIVVPDGMALDTV 709 Query: 691 GQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELGSK-SIKR 749 + IYWTD +RIE + DGS R + GL P+ IVL + MYW++ G+ I+R Sbjct: 710 ERRIYWTDIGRKRIERAHFDGSHREELERAGLDNPRGIVLARARRQMYWTDWGANPRIER 769 Query: 750 AAMDGSS-VSVFMEQVGRVHALAIDYERRAIYWA 782 A+MDG ++ +G + +A+D +YWA Sbjct: 770 ASMDGGQRKTIVSGALGWPNGIALDEPLSQLYWA 803 Score = 70.1 bits (164), Expect = 1e-11 Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 7/156 (4%) Query: 681 LVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWS 740 +V +A D + +YW+D Q+I + LDG II + P + LD + +YW+ Sbjct: 657 MVVAMAHDPVDKRVYWSDVGAQKISRAYLDGRGEETIITTDIVVPDGMALDTVERRIYWT 716 Query: 741 ELGSKSIKRAAMDGSSVSVFMEQVG--RVHALAIDYERRAIYWAALDP-PVVEFAFLNGT 797 ++G K I+RA DGS +E+ G + + RR +YW P +E A ++G Sbjct: 717 DIGRKRIERAHFDGSHREE-LERAGLDNPRGIVLARARRQMYWTDWGANPRIERASMDGG 775 Query: 798 GRQTLADN-IPMPYALALFN--DSVYWGDWNTGQIQ 830 R+T+ + P +AL +YW D +I+ Sbjct: 776 QRKTIVSGALGWPNGIALDEPLSQLYWADAKLDKIE 811 Score = 62.9 bits (146), Expect = 1e-09 Identities = 41/135 (30%), Positives = 63/135 (46%), Gaps = 7/135 (5%) Query: 714 RRAIIWQGLKKPKSIVLDPKKGYMYWSELGSKSIKRAAMDG-SSVSVFMEQVGRVHALAI 772 RR I QG+ ++ DP +YWS++G++ I RA +DG ++ + +A+ Sbjct: 648 RRLPITQGIMVV-AMAHDPVDKRVYWSDVGAQKISRAYLDGRGEETIITTDIVVPDGMAL 706 Query: 773 DYERRAIYWAALDPPVVEFAFLNGTGRQTLA----DNIPMPYALALFNDSVYWGDWNTGQ 828 D R IYW + +E A +G+ R+ L DN P LA +YW DW Sbjct: 707 DTVERRIYWTDIGRKRIERAHFDGSHREELERAGLDN-PRGIVLARARRQMYWTDWGANP 765 Query: 829 IQQARKTDGSNRKSI 843 + DG RK+I Sbjct: 766 RIERASMDGGQRKTI 780 Score = 59.3 bits (137), Expect = 2e-08 Identities = 44/160 (27%), Positives = 67/160 (41%), Gaps = 9/160 (5%) Query: 936 IPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHM 995 +P+T V A+ +DPV+K++YW D + I R + + P M Sbjct: 650 LPITQGIMVVAMAHDPVDKRVYWSDVGAQKISRAYLD-----GRGEETIITTDIVVPDGM 704 Query: 996 VLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGR 1055 LD + R +YWT R I D S + R PR + + +R + W D G Sbjct: 705 ALDTVERRIYWTDIGRKRIERAHFD-GSHREELERAGLDNPRGIVLARARRQMYWTDWGA 763 Query: 1056 G-AIMRANVDGTGRVELARADNA--TALALDQSAGTVYWA 1092 I RA++DG R + +ALD+ +YWA Sbjct: 764 NPRIERASMDGGQRKTIVSGALGWPNGIALDEPLSQLYWA 803 Score = 59.3 bits (137), Expect = 2e-08 Identities = 28/69 (40%), Positives = 42/69 (60%), Gaps = 2/69 (2%) Query: 434 MFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCN 493 ++WSD +K I RA LDG G +I+ + P+ +ALDTV ++YW D +IE + Sbjct: 670 VYWSDVGAQK--ISRAYLDGRGEETIITTDIVVPDGMALDTVERRIYWTDIGRKRIERAH 727 Query: 494 MDGTERKEL 502 DG+ R+EL Sbjct: 728 FDGSHREEL 736 Score = 57.6 bits (133), Expect = 6e-08 Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 5/105 (4%) Query: 111 AIAVVPEDGLMFWTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWV 170 A+A P D ++W+D G KI RA ++G + I+ +I P+G+ +D IYW Sbjct: 660 AMAHDPVDKRVYWSDVGA-QKISRAYLDG--RGEETIITTDIVVPDGMALDTVERRIYWT 716 Query: 171 DAKLQFVDVIDFNGEKRKRVVKGGLVYP--FALTFSNDKLYWTDW 213 D + ++ F+G R+ + + GL P L + ++YWTDW Sbjct: 717 DIGRKRIERAHFDGSHREELERAGLDNPRGIVLARARRQMYWTDW 761 Score = 57.6 bits (133), Expect = 6e-08 Identities = 40/143 (27%), Positives = 65/143 (45%), Gaps = 8/143 (5%) Query: 618 IGRLSIKNEYNDA----VIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVE 673 +G I Y D I D+ +AL ++YW+D K I R +GS E Sbjct: 675 VGAQKISRAYLDGRGEETIITTDIVVPDGMALDTVERRIYWTDIGRKRIERAHFDGSHRE 734 Query: 674 KIVEWLGL--VEGLAIDWSGQNIYWTDT-TTQRIEVSRLDGSSRRAIIWQGLKKPKSIVL 730 ++ E GL G+ + + + +YWTD RIE + +DG R+ I+ L P I L Sbjct: 735 EL-ERAGLDNPRGIVLARARRQMYWTDWGANPRIERASMDGGQRKTIVSGALGWPNGIAL 793 Query: 731 DPKKGYMYWSELGSKSIKRAAMD 753 D +YW++ I+ + ++ Sbjct: 794 DEPLSQLYWADAKLDKIETSDLE 816 Score = 36.7 bits (81), Expect = 0.11 Identities = 17/37 (45%), Positives = 23/37 (62%) Query: 53 GEKFKIVSEGLVTPTGIAIDWYTDKLYWTDGETNKIE 89 G++ IVS L P GIA+D +LYW D + +KIE Sbjct: 775 GQRKTIVSGALGWPNGIALDEPLSQLYWADAKLDKIE 811 Score = 30.7 bits (66), Expect = 7.4 Identities = 12/40 (30%), Positives = 22/40 (55%) Query: 469 SIALDTVNNKLYWGDARTHKIEVCNMDGTERKELHSNDII 508 ++A D V+ ++YW D KI +DG + + + DI+ Sbjct: 660 AMAHDPVDKRVYWSDVGAQKISRAYLDGRGEETIITTDIV 699 >SB_45709| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1112 Score = 129 bits (312), Expect = 1e-29 Identities = 94/348 (27%), Positives = 156/348 (44%), Gaps = 17/348 (4%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC---VEPEAFLVYSRKNIIGRLSIK 624 C NG C LC N + C C G EL D+K+C E E + S+K + S K Sbjct: 628 CKSFNGHCLQLCTNTKTSFYCSCFSGYELMDDRKSCRDINECEIPGMCSQKCYNTKGSFK 687 Query: 625 NEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEWLGLVEG 684 + + D + AL G + Y + +I +G ++ V+ L Sbjct: 688 CSCMEGYVLEPDGRRCKAL-----GPRPYVLFTDRNSIRLIMTDGKEYKQAVQGLKDART 742 Query: 685 LAIDWSGQNIYWTDTTTQRIEVSRL-DGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELG 743 L D +YWTD I+ +++ ++ + GL +P + +D MYW++ G Sbjct: 743 LGFDVKESMLYWTDKAATAIQKAKMVPDTTIETVHETGLVEPAGLAIDWVGRKMYWADPG 802 Query: 744 SKSIKRAAMDGS-SVSVFMEQVGRVHALAIDYERRAIYWAALDPPVVEFAFLNGTG-RQT 801 + +I+ + +DGS ++++ + + A+ +D +YW V++ LNGT R Sbjct: 803 ANTIEVSELDGSNTMTLISSGLDKPSAVVLD-PTEGLYWIDSKLDVIKHCNLNGTEVRVV 861 Query: 802 LADNIPMPYALALFNDSVYWGDWNTGQIQQARKTDGSNRKSIRKDLDYISDLKLYH-RAK 860 + I P A+ +F D +YW D + +I +A K G N + + D +YH + + Sbjct: 862 INTGIDNPTAITVFEDHIYWTD--SRKIYKANKFTGKNMTVLVNNAASPEDAHIYHPQRQ 919 Query: 861 SMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSE 908 S+ C + NGGCSHLCL + + Y C CP L D CS+ Sbjct: 920 PTASSPCAIRNGGCSHLCLISSN--KNKYSCNCPKDLFLQLDGKICSK 965 Score = 110 bits (264), Expect = 8e-24 Identities = 93/350 (26%), Positives = 148/350 (42%), Gaps = 20/350 (5%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQMLL--VVAQRSTISKI 317 CK N C LC + + C+C +G +L ++ + C D + + + +Q+ +K Sbjct: 628 CKSFNGHCLQLC--TNTKTSFYCSCFSGYELMDDRKS-CRDINECEIPGMCSQKCYNTKG 684 Query: 318 SLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQSVVVRSSG 377 S Y L D +R + P Y+ + D +I DG + V+ Sbjct: 685 SFKCSCMEGYVLE-PDGRRCKALGPRP---YVLFTD--RNSIRLIMTDGKEYKQAVQGLK 738 Query: 378 VPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIH-TELYDPRAIALHLTAGWMFW 436 ++ D +YWTD I A++ +H T L +P +A+ M+W Sbjct: 739 DARTLGFDVKESMLYWTDKAATAIQKAKMVPDTTIETVHETGLVEPAGLAIDWVGRKMYW 798 Query: 437 SDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDG 496 +D IE + LDGS + LIS L P+++ LD LYW D++ I+ CN++G Sbjct: 799 ADPGANT--IEVSELDGSNTMTLISSGLDKPSAVVLDPTEG-LYWIDSKLDVIKHCNLNG 855 Query: 497 TERKELHSNDIIHIFGXXXXXXXXXXXXMQKRTLDRINKNTGLDRQPVVEQMANMMGVKA 556 TE + + + I + R + + NK TG + +V A+ Sbjct: 856 TEVRVVINTGIDN--PTAITVFEDHIYWTDSRKIYKANKFTGKNMTVLVNNAASPEDAHI 913 Query: 557 FR-LGAPLGWNPCADDNGGCSHLCF--NRPDDYICGCPLGLELTADKKTC 603 + P +PCA NGGCSHLC + + Y C CP L L D K C Sbjct: 914 YHPQRQPTASSPCAIRNGGCSHLCLISSNKNKYSCNCPKDLFLQLDGKIC 963 Score = 99 bits (238), Expect = 1e-20 Identities = 69/262 (26%), Positives = 118/262 (45%), Gaps = 10/262 (3%) Query: 53 GEKFKIVSEGLVTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYR-KVLFWSEVDLARA 111 G+++K +GL + D LYWTD I+ +V + + + + Sbjct: 727 GKEYKQAVQGLKDARTLGFDVKESMLYWTDKAATAIQKAKMVPDTTIETVHETGLVEPAG 786 Query: 112 IAVVPEDGLMFWTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVD 171 +A+ M+W D G IE + ++G + ++ + P+ + +D L YW+D Sbjct: 787 LAIDWVGRKMYWADPGA-NTIEVSELDG--SNTMTLISSGLDKPSAVVLDPTEGL-YWID 842 Query: 172 AKLQFVDVIDFNGEKRKRVVKGGLVYPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIK 231 +KL + + NG + + V+ G+ P A+T D +YWTD + IY + G + Sbjct: 843 SKLDVIKHCNLNGTEVRVVINTGIDNPTAITVFEDHIYWTD--SRKIYKAN-KFTGKNMT 899 Query: 232 ELIKSHPVPADIKVYDESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLR 291 L+ + P D +Y RQ ++ PC N GCSHLCL+S + Y+C CP + L+ Sbjct: 900 VLVNNAASPEDAHIYHPQRQPTASS--PCAIRNGGCSHLCLISSNKNKYSCNCPKDLFLQ 957 Query: 292 ENSSTTCYDSPQMLLVVAQRST 313 + P L A S+ Sbjct: 958 LDGKICSKIKPPTTLPTALASS 979 Score = 85.0 bits (201), Expect = 3e-16 Identities = 65/236 (27%), Positives = 104/236 (44%), Gaps = 20/236 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSE--PEEFLLFAQKNAVG 922 N+C + G CS C T G ++C+C Y L D C P ++LF +N++ Sbjct: 667 NECEIP-GMCSQKCYNTKGS----FKCSCMEGYVLEPDGRRCKALGPRPYVLFTDRNSIR 721 Query: 923 RIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXX 982 IM E A + GLK+ R + +D E LYW D + +I++ + Sbjct: 722 LIMTDGKEYKQA---VQGLKDARTLGFDVKESMLYWTDKAATAIQKAKM----VPDTTIE 774 Query: 983 XXXXXGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFH 1042 GL P + +D +GR MYW ++I + +D S+T ++ P + Sbjct: 775 TVHETGLVEPAGLAIDWVGRKMYWADPGANTIEVSELD-GSNTMTLISSGLDKPSAVVLD 833 Query: 1043 QTKRYLIWNDVGRGAIMRANVDGTG-RVEL-ARADNATALALDQSAGTVYWAVSRQ 1096 T+ L W D I N++GT RV + DN TA+ + + +YW SR+ Sbjct: 834 PTEG-LYWIDSKLDVIKHCNLNGTEVRVVINTGIDNPTAITVFED--HIYWTDSRK 886 Score = 74.1 bits (174), Expect = 6e-13 Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 8/157 (5%) Query: 17 LEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIAIDWYTD 76 L+ + F +++++ W+D+ IQ T E + GLV P G+AIDW Sbjct: 737 LKDARTLGFDVKESMLYWTDKAATAIQKAKMVPDTTIET--VHETGLVEPAGLAIDWVGR 794 Query: 77 KLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIPKIERAG 136 K+YW D N IEV + L S +D A+ + P +GL +W D ++ I+ Sbjct: 795 KMYWADPGANTIEVSELDGSNTMTLISSGLDKPSAVVLDPTEGL-YWID-SKLDVIKHCN 852 Query: 137 MNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAK 173 +NG +V++ I P ITV ++ IYW D++ Sbjct: 853 LNGTEV--RVVINTGIDNPTAITVFEDH--IYWTDSR 885 Score = 48.0 bits (109), Expect = 5e-05 Identities = 55/238 (23%), Positives = 94/238 (39%), Gaps = 26/238 (10%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFL---LFAQK--N 919 ++C NG C LC T +T + C+C + Y L D +C + E + +QK N Sbjct: 626 DECKSFNGHCLQLCTNT----KTSFYCSCFSGYELMDDRKSCRDINECEIPGMCSQKCYN 681 Query: 920 AVGRIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXX 979 G + C + Y+ + +A+ P Y + D +SIR + Sbjct: 682 TKGSFKCS---CMEGYVLEPDGRRCKALGPRP-----YVLFTDRNSIRLI------MTDG 727 Query: 980 XXXXXXXXGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHL 1039 GL + DV +YWT +I + +++ + + P L Sbjct: 728 KEYKQAVQGLKDARTLGFDVKESMLYWTDKAATAIQKAKMVPDTTIETVHETGLVEPAGL 787 Query: 1040 AFHQTKRYLIWNDVGRGAIMRANVDGTGRVELARA--DNATALALDQSAGTVYWAVSR 1095 A R + W D G I + +DG+ + L + D +A+ LD + G +YW S+ Sbjct: 788 AIDWVGRKMYWADPGANTIEVSELDGSNTMTLISSGLDKPSAVVLDPTEG-LYWIDSK 844 Score = 43.2 bits (97), Expect = 0.001 Identities = 30/95 (31%), Positives = 33/95 (34%), Gaps = 17/95 (17%) Query: 1097 CDGQQDCEDGRDEAECGA-----CG-GDVRCA-----------DGTXXXXXXXXXXXXXX 1139 CDG DC D DE C C D CA DG Sbjct: 320 CDGMDDCGDSSDEDNCPTRPPYTCPPSDFTCANSQCVPNSFRCDGENDCGDRSDESGCKP 379 Query: 1140 XXXXXXDAFRCDEGLCIAARFVCDGRPQCADGSDE 1174 + FRCD+G CI + F CD C D SDE Sbjct: 380 TTTCSANEFRCDDGRCITSTFRCDREFDCTDRSDE 414 Score = 41.5 bits (93), Expect = 0.004 Identities = 31/96 (32%), Positives = 35/96 (36%), Gaps = 15/96 (15%) Query: 1094 SRQCDGQQDCEDGRDEAECG---ACGG-DVRCADGTXXXXXXXXXXXXXXXXXXXXDA-- 1147 S +CDG+ DC D DE+ C C + RC DG Sbjct: 359 SFRCDGENDCGDRSDESGCKPTTTCSANEFRCDDGRCITSTFRCDREFDCTDRSDERGCV 418 Query: 1148 --------FRCD-EGLCIAARFVCDGRPQCADGSDE 1174 F C G CI RF CD R C DGSDE Sbjct: 419 NKTCAPYEFTCAFSGRCIPGRFRCDHRSDCLDGSDE 454 Score = 41.5 bits (93), Expect = 0.004 Identities = 28/78 (35%), Positives = 31/78 (39%), Gaps = 26/78 (33%) Query: 1097 CDGQQDCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEGLCI 1156 CDG++DC DG DEA CG G C+ D F C CI Sbjct: 490 CDGERDCLDGSDEAGCGTIG----CS----------------------SDEFTCTNQKCI 523 Query: 1157 AARFVCDGRPQCADGSDE 1174 CDG C DGSDE Sbjct: 524 PLPQKCDGTDNCGDGSDE 541 Score = 38.3 bits (85), Expect = 0.037 Identities = 25/85 (29%), Positives = 30/85 (35%), Gaps = 4/85 (4%) Query: 1095 RQCDGQQDCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEG- 1153 ++CDG +C DG DE C + D FRC Sbjct: 527 QKCDGTDNCGDGSDEKMCPTPSVPPQ---PDIAYQPVSGDNTTQPGQVCPRDHFRCGSST 583 Query: 1154 LCIAARFVCDGRPQCADGSDEAPAA 1178 +CIA VCD P C G DE A Sbjct: 584 ICIANSKVCDATPHCPHGEDERNCA 608 Score = 37.9 bits (84), Expect = 0.049 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Query: 1150 CDEGLCIAARFVCDGRPQCADGSDE--APAACAYGHTDQVNGIH 1191 C+ G CI A ++CDG C D SDE P A G + H Sbjct: 137 CNNGQCIKASWLCDGASDCQDNSDEMNCPLTLAPGRNSRARTAH 180 Score = 35.1 bits (77), Expect = 0.34 Identities = 14/27 (51%), Positives = 18/27 (66%), Gaps = 1/27 (3%) Query: 1150 CDEGL-CIAARFVCDGRPQCADGSDEA 1175 C +G C+ R++CDG C DGSDEA Sbjct: 477 CADGNGCVHRRWICDGERDCLDGSDEA 503 Score = 33.1 bits (72), Expect = 1.4 Identities = 11/25 (44%), Positives = 14/25 (56%) Query: 1150 CDEGLCIAARFVCDGRPQCADGSDE 1174 C G C+ ++CDG C D SDE Sbjct: 308 CRNGRCVLKEWLCDGMDDCGDSSDE 332 Score = 31.9 bits (69), Expect = 3.2 Identities = 12/28 (42%), Positives = 14/28 (50%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEA 1175 F C C+ F CDG C D SDE+ Sbjct: 348 FTCANSQCVPNSFRCDGENDCGDRSDES 375 >SB_23513| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 340 Score = 126 bits (304), Expect = 1e-28 Identities = 71/191 (37%), Positives = 103/191 (53%), Gaps = 7/191 (3%) Query: 22 AVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIAIDWYTDKLYWT 81 A+D H K L+ WSD ++I+ N TGE K+VS+ G+A+DW T LYWT Sbjct: 108 ALDVHVEKMLVFWSDVGDKVIKRGNL---ITGEVVKVVSDVQAQHDGVAVDWATGLLYWT 164 Query: 82 DGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIPKIERAGMNGDP 141 + + IEV + +RK L + + I V P GLMFWTD E PKIERA + G Sbjct: 165 NRDKKAIEVAKLDGSFRKTLIKDNLVGPKGIVVDPRTGLMFWTD-KETPKIERATLAG-- 221 Query: 142 ATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVVKGGLVYPFAL 201 R +V + P G+ DY ++ +YW D L +++ ID++G R+ + K G V+PF + Sbjct: 222 RDRISLVTTALKRPEGLVNDYASNRLYWCDPILDYIESIDYDGGNRRVLYKNG-VHPFDM 280 Query: 202 TFSNDKLYWTD 212 L W+D Sbjct: 281 AIYGHMLIWSD 291 Score = 116 bits (278), Expect = 2e-25 Identities = 63/223 (28%), Positives = 111/223 (49%), Gaps = 2/223 (0%) Query: 617 IIGRLSIKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCS-VNGSAVEKI 675 I R +I V+ + K++ AL ++V ++WSD K I R + + G V+ + Sbjct: 83 ITARHAIGLSRRGPVVGFQGQKKIRALDVHVEKMLVFWSDVGDKVIKRGNLITGEVVKVV 142 Query: 676 VEWLGLVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKG 735 + +G+A+DW+ +YWT+ + IEV++LDGS R+ +I L PK IV+DP+ G Sbjct: 143 SDVQAQHDGVAVDWATGLLYWTNRDKKAIEVAKLDGSFRKTLIKDNLVGPKGIVVDPRTG 202 Query: 736 YMYWSELGSKSIKRAAMDG-SSVSVFMEQVGRVHALAIDYERRAIYWAALDPPVVEFAFL 794 M+W++ + I+RA + G +S+ + R L DY +YW +E Sbjct: 203 LMFWTDKETPKIERATLAGRDRISLVTTALKRPEGLVNDYASNRLYWCDPILDYIESIDY 262 Query: 795 NGTGRQTLADNIPMPYALALFNDSVYWGDWNTGQIQQARKTDG 837 +G R+ L N P+ +A++ + W D +++ G Sbjct: 263 DGGNRRVLYKNGVHPFDMAIYGHMLIWSDLGINTVERVDMRTG 305 Score = 111 bits (267), Expect = 3e-24 Identities = 70/233 (30%), Positives = 109/233 (46%), Gaps = 6/233 (2%) Query: 335 KRTLTVDFDPKTEYIYWADGLAKTISKARL-DGSDQSVVVRSSGVPDSIAIDPLSRKIYW 393 K+ +D + ++W+D K I + L G VV D +A+D + +YW Sbjct: 104 KKIRALDVHVEKMLVFWSDVGDKVIKRGNLITGEVVKVVSDVQAQHDGVAVDWATGLLYW 163 Query: 394 TDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKPKIERANLDG 453 T+ I VA+LDGS+ K +I L P+ I + G MFW+D ++ PKIERA L G Sbjct: 164 TNRDKKAIEVAKLDGSFRKTLIKDNLVGPKGIVVDPRTGLMFWTD--KETPKIERATLAG 221 Query: 454 SGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERKELHSNDIIHIFGX 513 R+ L++ L P + D +N+LYW D IE + DG R+ L+ N +H F Sbjct: 222 RDRISLVTTALKRPEGLVNDYASNRLYWCDPILDYIESIDYDGGNRRVLYKNG-VHPFDM 280 Query: 514 XXXXXXXXXXXMQKRTLDRINKNTGLDRQPVVEQMAN-MMGVKAFRLG-APLG 564 + T++R++ TG+ +V N G+ L P+G Sbjct: 281 AIYGHMLIWSDLGINTVERVDMRTGVKLSTLVTLKDNWATGIAVLHLSRQPIG 333 Score = 49.2 bits (112), Expect = 2e-05 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 5/105 (4%) Query: 110 RAIAVVPEDGLMFWTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYW 169 RA+ V E L+FW+D G+ I+R + + +V D +G+ VD+ L+YW Sbjct: 107 RALDVHVEKMLVFWSDVGD-KVIKRGNLITGEVVK--VVSDVQAQHDGVAVDWATGLLYW 163 Query: 170 VDAKLQFVDVIDFNGEKRKRVVKGGLVYPFALTFS--NDKLYWTD 212 + + ++V +G RK ++K LV P + ++WTD Sbjct: 164 TNRDKKAIEVAKLDGSFRKTLIKDNLVGPKGIVVDPRTGLMFWTD 208 Score = 34.3 bits (75), Expect = 0.60 Identities = 27/119 (22%), Positives = 48/119 (40%), Gaps = 9/119 (7%) Query: 945 RAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVLGRTM 1004 + I DP ++W D ++ I R ++ L RP +V D + Sbjct: 193 KGIVVDPRTGLMFWTDKETPKIERATLA-----GRDRISLVTTALKRPEGLVNDYASNRL 247 Query: 1005 YWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGAIMRANV 1063 YW D I SID + ++ + + P +A + LIW+D+G + R ++ Sbjct: 248 YWCDPILDYIE--SIDYDGGNRRVLYKNGVHPFDMAIY--GHMLIWSDLGINTVERVDM 302 Score = 32.3 bits (70), Expect = 2.4 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 4/58 (6%) Query: 1037 RHLAFHQTKRYLIWNDVGRGAIMRANVDGTGRVELARAD---NATALALDQSAGTVYW 1091 R L H K + W+DVG I R N+ TG V +D +A+D + G +YW Sbjct: 107 RALDVHVEKMLVFWSDVGDKVIKRGNLI-TGEVVKVVSDVQAQHDGVAVDWATGLLYW 163 >SB_26126| Best HMM Match : Ldl_recept_b (HMM E-Value=3e-24) Length = 652 Score = 107 bits (258), Expect = 4e-23 Identities = 58/170 (34%), Positives = 93/170 (54%), Gaps = 4/170 (2%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYSRKNIIGRLSIKNEY 627 C D NG CS C + Y C C G +L + CV LVYS + I +++ Sbjct: 252 CKDHNGHCSQKCNDLTLGYNCSCFSGYKLQG-ARLCVGTLPSLVYSSQFSIRNVTVSGAI 310 Query: 628 NDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGS-AVEKIVEWLGLVEGLA 686 + A++ + K V L + ++W+D+K + INR ++GS +VE+IV + + + + Sbjct: 311 SQAIVSGR--KGVVGLDYDYKSNLIFWTDAKAEKINRARLDGSGSVEEIVGDVKVPDDVT 368 Query: 687 IDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGY 736 +DWSG+ IYWTD IEV+ L G+ R + GL +P++IV+DP G+ Sbjct: 369 VDWSGRKIYWTDGEQNMIEVAELTGAHRMTLFSSGLDEPRAIVVDPSAGF 418 Score = 95.9 bits (228), Expect = 2e-19 Identities = 65/198 (32%), Positives = 99/198 (50%), Gaps = 16/198 (8%) Query: 244 KVYDESRQIISAEDYP-------CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSST 296 KV D +R ED P CK +N CS C + GYNC+C +G KL+ + Sbjct: 229 KVCDGTRDCQDGEDEPLRCNIDECKDHNGHCSQKC--NDLTLGYNCSCFSGYKLQ--GAR 284 Query: 297 TCYDSPQMLLVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLA 356 C + L+ +Q S I +++ + K + +D+D K+ I+W D A Sbjct: 285 LCVGTLPSLVYSSQFS-IRNVTVSGAISQAI---VSGRKGVVGLDYDYKSNLIFWTDAKA 340 Query: 357 KTISKARLDGSDQ-SVVVRSSGVPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVII 415 + I++ARLDGS +V VPD + +D RKIYWTD + I VA L G++ + Sbjct: 341 EKINRARLDGSGSVEEIVGDVKVPDDVTVDWSGRKIYWTDGEQNMIEVAELTGAHRMTLF 400 Query: 416 HTELYDPRAIALHLTAGW 433 + L +PRAI + +AG+ Sbjct: 401 SSGLDEPRAIVVDPSAGF 418 Score = 81.0 bits (191), Expect = 5e-15 Identities = 55/185 (29%), Positives = 83/185 (44%), Gaps = 18/185 (9%) Query: 434 MFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCN 493 +FW+D K KI RA LDGSG V I + P+ + +D K+YW D + IEV Sbjct: 333 IFWTD--AKAEKINRARLDGSGSVEEIVGDVKVPDDVTVDWSGRKIYWTDGEQNMIEVAE 390 Query: 494 MDGTERKELHSNDIIH--------IFGXXXXXXXXXXXXMQKRTL-DRINKNTGLDRQPV 544 + G R L S+ + G M +T+ + + R P+ Sbjct: 391 LTGAHRMTLFSSGLDEPRAIVVDPSAGFASSRLLTIAMAMSYKTVKSHVTLVALIPRVPL 450 Query: 545 VEQMANMMGVKAFRLGAPLGW----NPCADDNGGCSHLCF--NRPDDYICGCPLGLELTA 598 ++ + + F+ G+ N C D+NGGCSHLC P + C CP G+ +++ Sbjct: 451 YCRI-RCIATRVFQNTICFGFLFLPNRCGDNNGGCSHLCLLAAAPRKFSCKCPNGMNMSS 509 Query: 599 DKKTC 603 D KTC Sbjct: 510 DGKTC 514 Score = 74.5 bits (175), Expect = 5e-13 Identities = 50/198 (25%), Positives = 88/198 (44%), Gaps = 20/198 (10%) Query: 117 EDGLMFWTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQF 176 + L+FWTD + KI RA ++G + +++ ++ P+ +TVD++ IYW D + Sbjct: 329 KSNLIFWTD-AKAEKINRARLDGSGSVEEIV--GDVKVPDDVTVDWSGRKIYWTDGEQNM 385 Query: 177 VDVIDFNGEKRKRVVKGGLVYPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKS 236 ++V + G R + GL P A+ + + + T +A + +K + Sbjct: 386 IEVAELTGAHRMTLFSSGLDEPRAIVVDPS----AGFASSRLLTIAMAMSYKTVKSHVTL 441 Query: 237 HPVPADIKVYDESRQIISAE------------DYPCKKNNAGCSHLCLLSPDPPGYNCAC 284 + + +Y R I + C NN GCSHLCLL+ P ++C C Sbjct: 442 VALIPRVPLYCRIRCIATRVFQNTICFGFLFLPNRCGDNNGGCSHLCLLAAAPRKFSCKC 501 Query: 285 PTGVKLRENSSTTCYDSP 302 P G+ + + TC P Sbjct: 502 PNGMNM-SSDGKTCTGQP 518 Score = 71.3 bits (167), Expect = 4e-12 Identities = 39/97 (40%), Positives = 53/97 (54%), Gaps = 3/97 (3%) Query: 23 VDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIAIDWYTDKLYWTD 82 +D+ Y+ NLI W+D K E I + + G +IV + V P + +DW K+YWTD Sbjct: 324 LDYDYKSNLIFWTDAKAEKINRARLDGS--GSVEEIVGDVKV-PDDVTVDWSGRKIYWTD 380 Query: 83 GETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDG 119 GE N IEV + +R LF S +D RAI V P G Sbjct: 381 GEQNMIEVAELTGAHRMTLFSSGLDEPRAIVVDPSAG 417 Score = 66.5 bits (155), Expect = 1e-10 Identities = 60/231 (25%), Positives = 103/231 (44%), Gaps = 26/231 (11%) Query: 694 IYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSELGSKSIKRAAMD 753 +Y + + + + VS G+ +AI+ G K + D K ++W++ ++ I RA +D Sbjct: 294 VYSSQFSIRNVTVS---GAISQAIV-SGRKGVVGLDYDYKSNLIFWTDAKAEKINRARLD 349 Query: 754 GS-SVSVFMEQVGRVHALAIDYERRAIYWAALDPPVVEFAFLNGTGRQTL-ADNIPMPYA 811 GS SV + V + +D+ R IYW + ++E A L G R TL + + P A Sbjct: 350 GSGSVEEIVGDVKVPDDVTVDWSGRKIYWTDGEQNMIEVAELTGAHRMTLFSSGLDEPRA 409 Query: 812 LALFNDSVYWGDWNTGQIQQARKTDGSNRKSIRKDLDYISDLKLYHRAKSMGS------- 864 + + + G ++ + A KS + I + LY R + + + Sbjct: 410 IVVDPSA---GFASSRLLTIAMAMSYKTVKSHVTLVALIPRVPLYCRIRCIATRVFQNTI 466 Query: 865 --------NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCS 907 N+CG +NGGCSHLCL + + C CP ++ D TC+ Sbjct: 467 CFGFLFLPNRCGDNNGGCSHLCLLAAAPRK--FSCKCPNGMNMSSDGKTCT 515 Score = 52.8 bits (121), Expect = 2e-06 Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 1/114 (0%) Query: 661 TINRCSVNGSAVEKIVEWLGLVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQ 720 +I +V+G+ + IV V GL D+ I+WTD ++I +RLDGS I Sbjct: 300 SIRNVTVSGAISQAIVSGRKGVVGLDYDYKSNLIFWTDAKAEKINRARLDGSGSVEEIVG 359 Query: 721 GLKKPKSIVLDPKKGYMYWSELGSKSIKRAAMDGS-SVSVFMEQVGRVHALAID 773 +K P + +D +YW++ I+ A + G+ +++F + A+ +D Sbjct: 360 DVKVPDDVTVDWSGRKIYWTDGEQNMIEVAELTGAHRMTLFSSGLDEPRAIVVD 413 Score = 49.2 bits (112), Expect = 2e-05 Identities = 34/105 (32%), Positives = 52/105 (49%), Gaps = 3/105 (2%) Query: 369 QSVVVRSSGVPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALH 428 Q++V GV + D S I+WTD + IN ARLDGS I ++ P + + Sbjct: 312 QAIVSGRKGVV-GLDYDYKSNLIFWTDAKAEKINRARLDGSGSVEEIVGDVKVPDDVTVD 370 Query: 429 LTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALD 473 + ++W+D + IE A L G+ R+ L S L P +I +D Sbjct: 371 WSGRKIYWTDGEQN--MIEVAELTGAHRMTLFSSGLDEPRAIVVD 413 Score = 48.4 bits (110), Expect = 3e-05 Identities = 34/155 (21%), Positives = 66/155 (42%), Gaps = 13/155 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFLLFAQKNAVGRI 924 ++C NG CS C D+ Y C+C + Y+L + C L+++ + ++ + Sbjct: 250 DECKDHNGHCSQKC----NDLTLGYNCSCFSGYKLQGARL-CVGTLPSLVYSSQFSIRNV 304 Query: 925 MVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXX 984 V+ G + A + +G K V ++YD ++W D + I R + Sbjct: 305 TVS-GAISQAIV--SGRKGVVGLDYDYKSNLIFWTDAKAEKINRARLD-----GSGSVEE 356 Query: 985 XXXGLSRPYHMVLDVLGRTMYWTCADRDSINATSI 1019 + P + +D GR +YWT +++ I + Sbjct: 357 IVGDVKVPDDVTVDWSGRKIYWTDGEQNMIEVAEL 391 Score = 41.1 bits (92), Expect = 0.005 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 2/58 (3%) Query: 157 GITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVVKGGLVYPFALT--FSNDKLYWTD 212 G+ DY ++LI+W DAK + ++ +G + G + P +T +S K+YWTD Sbjct: 323 GLDYDYKSNLIFWTDAKAEKINRARLDGSGSVEEIVGDVKVPDDVTVDWSGRKIYWTD 380 Score = 34.7 bits (76), Expect = 0.45 Identities = 18/43 (41%), Positives = 19/43 (44%), Gaps = 2/43 (4%) Query: 1148 FRCDE-GLCIAARFVCDGRPQCADGSDEAPAACAYGHTDQVNG 1189 F+C G CI VCDG C DG DE P C NG Sbjct: 216 FKCQSTGRCIPESKVCDGTRDCQDGEDE-PLRCNIDECKDHNG 257 Score = 34.7 bits (76), Expect = 0.45 Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 3/114 (2%) Query: 48 NETYTGEKFKIVSEGLVTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVD 107 N T +G + + G G+ D+ ++ ++WTD + KI + +V Sbjct: 303 NVTVSGAISQAIVSGRKGVVGLDYDYKSNLIFWTDAKAEKINRARLDGSGSVEEIVGDVK 362 Query: 108 LARAIAVVPEDGLMFWTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVD 161 + + V ++WTD GE IE A + G A R + + P I VD Sbjct: 363 VPDDVTVDWSGRKIYWTD-GEQNMIEVAELTG--AHRMTLFSSGLDEPRAIVVD 413 Score = 30.3 bits (65), Expect = 9.8 Identities = 10/16 (62%), Positives = 13/16 (81%) Query: 1094 SRQCDGQQDCEDGRDE 1109 S+ CDG +DC+DG DE Sbjct: 228 SKVCDGTRDCQDGEDE 243 >SB_47029| Best HMM Match : Ldl_recept_b (HMM E-Value=8.2e-28) Length = 300 Score = 99.5 bits (237), Expect = 1e-20 Identities = 51/164 (31%), Positives = 85/164 (51%), Gaps = 3/164 (1%) Query: 64 VTPTGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFW 123 V+ IAIDW +Y+ D + I V + +YR+ + S ++ IAV P G +FW Sbjct: 50 VSVRAIAIDWVAKNIYFIDSTAHAIMVATADGRYRRTVVSSGLEQPAGIAVDPISGRIFW 109 Query: 124 TDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFN 183 TD G PK+ + ++G A + +V + P G+ +D+ + ++YW D + +D I + Sbjct: 110 TDGGYSPKVMSSALDG--ADPRSLVTSELISPAGLAIDHTSDVLYWADTRTGRIDAIGLD 167 Query: 184 GEKRKRVVKGGLVYPFALTFSNDKLYWTDWQNWSIYTWDIAANG 227 G R R V GL+ P++L D LY + +N ++Y D G Sbjct: 168 GNGR-RTVWSGLMQPYSLAVQGDWLYVSGLRNGTVYRMDKLGRG 210 Score = 96.7 bits (230), Expect = 1e-19 Identities = 52/169 (30%), Positives = 92/169 (54%), Gaps = 3/169 (1%) Query: 669 GSAVEKIVEWLGL-VEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKS 727 G A+ + +++ + V +AIDW +NIY+ D+T I V+ DG RR ++ GL++P Sbjct: 38 GPALVQTIDFPAVSVRAIAIDWVAKNIYFIDSTAHAIMVATADGRYRRTVVSSGLEQPAG 97 Query: 728 IVLDPKKGYMYWSELG-SKSIKRAAMDGSSV-SVFMEQVGRVHALAIDYERRAIYWAALD 785 I +DP G ++W++ G S + +A+DG+ S+ ++ LAID+ +YWA Sbjct: 98 IAVDPISGRIFWTDGGYSPKVMSSALDGADPRSLVTSELISPAGLAIDHTSDVLYWADTR 157 Query: 786 PPVVEFAFLNGTGRQTLADNIPMPYALALFNDSVYWGDWNTGQIQQARK 834 ++ L+G GR+T+ + PY+LA+ D +Y G + + K Sbjct: 158 TGRIDAIGLDGNGRRTVWSGLMQPYSLAVQGDWLYVSGLRNGTVYRMDK 206 Score = 85.0 bits (201), Expect = 3e-16 Identities = 42/124 (33%), Positives = 70/124 (56%), Gaps = 1/124 (0%) Query: 381 SIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWN 440 +IAID +++ IY+ D I VA DG Y + ++ + L P IA+ +G +FW+D Sbjct: 54 AIAIDWVAKNIYFIDSTAHAIMVATADGRYRRTVVSSGLEQPAGIAVDPISGRIFWTDGG 113 Query: 441 EKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERK 500 PK+ + LDG+ L++ +L P +A+D ++ LYW D RT +I+ +DG R+ Sbjct: 114 YS-PKVMSSALDGADPRSLVTSELISPAGLAIDHTSDVLYWADTRTGRIDAIGLDGNGRR 172 Query: 501 ELHS 504 + S Sbjct: 173 TVWS 176 Score = 68.9 bits (161), Expect = 2e-11 Identities = 47/140 (33%), Positives = 77/140 (55%), Gaps = 9/140 (6%) Query: 336 RTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQSVVVRSSGV--PDSIAIDPLSRKIYW 393 R + +D+ K IY+ D A I A DG + VV SSG+ P IA+DP+S +I+W Sbjct: 53 RAIAIDWVAKN--IYFIDSTAHAIMVATADGRYRRTVV-SSGLEQPAGIAVDPISGRIFW 109 Query: 394 TD-PVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKPKIERANLD 452 TD + + LDG+ + ++ +EL P +A+ T+ ++W+D + +I+ LD Sbjct: 110 TDGGYSPKVMSSALDGADPRSLVTSELISPAGLAIDHTSDVLYWAD--TRTGRIDAIGLD 167 Query: 453 GSGRVLLISEKLTWPNSIAL 472 G+GR + S L P S+A+ Sbjct: 168 GNGRRTVWS-GLMQPYSLAV 186 Score = 48.0 bits (109), Expect = 5e-05 Identities = 32/126 (25%), Positives = 51/126 (40%), Gaps = 5/126 (3%) Query: 943 NVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXXXGLSRPYHMVLDVLGR 1002 +VRAI D V K +Y++D +H+I GL +P + +D + Sbjct: 51 SVRAIAIDWVAKNIYFIDSTAHAIM-----VATADGRYRRTVVSSGLEQPAGIAVDPISG 105 Query: 1003 TMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGAIMRAN 1062 ++WT +S + + +V + + P LA T L W D G I Sbjct: 106 RIFWTDGGYSPKVMSSALDGADPRSLVTSELISPAGLAIDHTSDVLYWADTRTGRIDAIG 165 Query: 1063 VDGTGR 1068 +DG GR Sbjct: 166 LDGNGR 171 Score = 43.6 bits (98), Expect = 0.001 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%) Query: 9 RITTIAKDLEQGTAVDFHYRKNLICWSD--QKPELIQCMNYNETYTGEKFKIVSEGLVTP 66 R T ++ LEQ + I W+D P+++ + + +V+ L++P Sbjct: 84 RRTVVSSGLEQPAGIAVDPISGRIFWTDGGYSPKVMS----SALDGADPRSLVTSELISP 139 Query: 67 TGIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAV 114 G+AID +D LYW D T +I+ I + R+ + WS + ++AV Sbjct: 140 AGLAIDHTSDVLYWADTRTGRIDAIGLDGNGRRTV-WSGLMQPYSLAV 186 Score = 31.9 bits (69), Expect = 3.2 Identities = 22/104 (21%), Positives = 45/104 (43%), Gaps = 4/104 (3%) Query: 995 MVLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVG 1054 + +D + + +Y+ + +I + D V+ G P +A + W D G Sbjct: 55 IAIDWVAKNIYFIDSTAHAIMVATADGRYRRTVVSSGLEQ-PAGIAVDPISGRIFWTDGG 113 Query: 1055 RGA-IMRANVDGTGRVELARAD--NATALALDQSAGTVYWAVSR 1095 +M + +DG L ++ + LA+D ++ +YWA +R Sbjct: 114 YSPKVMSSALDGADPRSLVTSELISPAGLAIDHTSDVLYWADTR 157 Score = 31.1 bits (67), Expect = 5.6 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 2/63 (3%) Query: 447 ERANLDGSGRVLL--ISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERKELHS 504 ERA D G L+ I +IA+D V +Y+ D+ H I V DG R+ + S Sbjct: 30 ERARRDAPGPALVQTIDFPAVSVRAIAIDWVAKNIYFIDSTAHAIMVATADGRYRRTVVS 89 Query: 505 NDI 507 + + Sbjct: 90 SGL 92 Score = 30.3 bits (65), Expect = 9.8 Identities = 15/60 (25%), Positives = 32/60 (53%), Gaps = 2/60 (3%) Query: 636 DLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEWLGLVEGLAIDWSGQNIY 695 +L + LA+ + LYW+D++T I+ ++G+ + W GL++ ++ G +Y Sbjct: 135 ELISPAGLAIDHTSDVLYWADTRTGRIDAIGLDGNGRRTV--WSGLMQPYSLAVQGDWLY 192 >SB_47789| Best HMM Match : Ldl_recept_a (HMM E-Value=4.2e-34) Length = 262 Score = 96.7 bits (230), Expect = 1e-19 Identities = 61/174 (35%), Positives = 89/174 (51%), Gaps = 31/174 (17%) Query: 726 KSIVLDPKKGYMYWSELGSKSIKRAAMDGSSVSV-FMEQVGRVHALAIDYERRAIYWAAL 784 + + LD +YW + G+K I+ + DG V F + + R AL +D Sbjct: 14 EGLALDWLSNNLYWVDAGAKKIEVSRKDGRYRKVLFKDNLDRPRALVLD----------- 62 Query: 785 DPPVVEFAFLNGTGRQTLADNIPMPYALALFNDSVYWGDWNTGQIQQARKTDGSNRKSIR 844 PVV T R +IP PYA+++F +YW DW+T IQ+A K DGS+R +I+ Sbjct: 63 --PVV-------TSR-----SIPHPYAISIFQQYMYWDDWSTRSIQRALKRDGSSRFTIK 108 Query: 845 KDLDYISDLKLYHRAKSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYR 898 L + DLK++H+ G+N C + C LCLPTP Y+CACP + R Sbjct: 109 SGLTGVMDLKVFHQDAQTGNNSCSL-RSPCDFLCLPTP----NSYQCACPDNMR 157 Score = 69.3 bits (162), Expect = 2e-11 Identities = 37/91 (40%), Positives = 52/91 (57%), Gaps = 16/91 (17%) Query: 682 VEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPK-------- 733 VEGLA+DW N+YW D ++IEVSR DG R+ + L +P+++VLDP Sbjct: 13 VEGLALDWLSNNLYWVDAGAKKIEVSRKDGRYRKVLFKDNLDRPRALVLDPVVTSRSIPH 72 Query: 734 -------KGYMYWSELGSKSIKRA-AMDGSS 756 + YMYW + ++SI+RA DGSS Sbjct: 73 PYAISIFQQYMYWDDWSTRSIQRALKRDGSS 103 Score = 56.4 bits (130), Expect = 1e-07 Identities = 41/139 (29%), Positives = 53/139 (38%), Gaps = 18/139 (12%) Query: 470 IALDTVNNKLYWGDARTHKIEVCNMDGTERKELH-----------------SNDIIHIFG 512 +ALD ++N LYW DA KIEV DG RK L S I H + Sbjct: 16 LALDWLSNNLYWVDAGAKKIEVSRKDGRYRKVLFKDNLDRPRALVLDPVVTSRSIPHPYA 75 Query: 513 XXXXXXXXXXXXMQKRTLDRINKNTGLDRQPVVEQMANMMGVKAFRLGAPLGWNPCADDN 572 R++ R K G R + + +M +K F A G N C+ Sbjct: 76 ISIFQQYMYWDDWSTRSIQRALKRDGSSRFTIKSGLTGVMDLKVFHQDAQTGNNSCSL-R 134 Query: 573 GGCSHLCFNRPDDYICGCP 591 C LC P+ Y C CP Sbjct: 135 SPCDFLCLPTPNSYQCACP 153 Score = 50.4 bits (115), Expect = 9e-06 Identities = 22/49 (44%), Positives = 30/49 (61%) Query: 68 GIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVP 116 G+A+DW ++ LYW D KIEV +YRKVLF +D RA+ + P Sbjct: 15 GLALDWLSNNLYWVDAGAKKIEVSRKDGRYRKVLFKDNLDRPRALVLDP 63 Score = 48.8 bits (111), Expect = 3e-05 Identities = 38/150 (25%), Positives = 64/150 (42%), Gaps = 24/150 (16%) Query: 157 GITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVVKGGL-----------------VYPF 199 G+ +D+ ++ +YWVDA + ++V +G RK + K L +P+ Sbjct: 15 GLALDWLSNNLYWVDAGAKKIEVSRKDGRYRKVLFKDNLDRPRALVLDPVVTSRSIPHPY 74 Query: 200 ALTFSNDKLYWTDWQNWSIYTWDIAANGPKIKELIKSHPVPADIKVYDESRQIISAEDYP 259 A++ +YW DW SI + +G + D+KV+ + Q + Sbjct: 75 AISIFQQYMYWDDWSTRSIQR-ALKRDGSSRFTIKSGLTGVMDLKVFHQDAQ---TGNNS 130 Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVK 289 C + C LCL P P Y CACP ++ Sbjct: 131 CSLRSP-CDFLCL--PTPNSYQCACPDNMR 157 Score = 48.0 bits (109), Expect = 5e-05 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 18/98 (18%) Query: 380 DSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAI-------------- 425 + +A+D LS +YW D I V+R DG Y KV+ L PRA+ Sbjct: 14 EGLALDWLSNNLYWVDAGAKKIEVSRKDGRYRKVLFKDNLDRPRALVLDPVVTSRSIPHP 73 Query: 426 -ALHLTAGWMFWSDWNEKKPKIERA-NLDGSGRVLLIS 461 A+ + +M+W DW+ + I+RA DGS R + S Sbjct: 74 YAISIFQQYMYWDDWSTR--SIQRALKRDGSSRFTIKS 109 Score = 35.5 bits (78), Expect = 0.26 Identities = 13/27 (48%), Positives = 18/27 (66%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 F+CD G CI++++ CD C D SDE Sbjct: 232 FKCDNGRCISSKWRCDHDNDCGDMSDE 258 Score = 32.3 bits (70), Expect = 2.4 Identities = 12/27 (44%), Positives = 15/27 (55%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 F+C G CI + + CD C D SDE Sbjct: 193 FKCGNGKCIPSSWKCDHDNDCGDNSDE 219 Score = 30.7 bits (66), Expect = 7.4 Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 2/62 (3%) Query: 414 IIHTELYDPRAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALD 473 ++H +AL + ++W D KK ++ R DG R +L + L P ++ LD Sbjct: 5 VLHGITQQVEGLALDWLSNNLYWVDAGAKKIEVSRK--DGRYRKVLFKDNLDRPRALVLD 62 Query: 474 TV 475 V Sbjct: 63 PV 64 >SB_18560| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1937 Score = 88.2 bits (209), Expect = 3e-17 Identities = 81/283 (28%), Positives = 124/283 (43%), Gaps = 44/283 (15%) Query: 23 VDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIV--SEGLVTPTGIAIDWYTDKLYW 80 VD+ + I W+ E+++ Y G K ++V + + +P GIA+DW +YW Sbjct: 1475 VDYDCVEEYIYWT----EIMEGCIMRAKYDGTKLEVVIPRKQVKSPEGIAVDWMGRNIYW 1530 Query: 81 TDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIPKIERAGMNGD 140 TD + IEV + R+VL + +D RAI V P +G D G +P NG Sbjct: 1531 TDTGLDVIEVAGMNGSNRRVLISNALDDPRAILVDPPNG-----DLG-LP-------NG- 1576 Query: 141 PATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVVKGGLVYPFA 200 +VR N N L + DA + +D ++V+ + YP+ Sbjct: 1577 ----LTLVRAN------------NELCF-TDAGTWSIRCVDLGALNVRKVIY-PIAYPYG 1618 Query: 201 LTFSNDKLYWTDWQNWSIYT--WDIAANGPKIKELIKSHPVPADIKVYDESRQIISAEDY 258 + N L+WTDW N + D G +K + D+K + SA+ Y Sbjct: 1619 IASFNRTLFWTDWMNNKVQRIGMDSKDPGVPLKTYVGQSGKIFDVKAVQPCPKKASAK-Y 1677 Query: 259 PCKKNNAGCSHLCLLSPDPPGYNCACPTGV-KLRENSSTTCYD 300 PC+ NN GC LCLL P G+ C+CP + + + T C D Sbjct: 1678 PCEVNNGGCMGLCLLRPG--GHTCSCPVHMYTVTTDKGTICKD 1718 Score = 83.0 bits (196), Expect = 1e-15 Identities = 58/194 (29%), Positives = 87/194 (44%), Gaps = 11/194 (5%) Query: 238 PVPADIKVYDESRQIISAEDYPCKKNNAGCSHLCLLSPDP----PGYNCACPTGVKLREN 293 P P + K + + + KK N C LC+ + C CP G Sbjct: 1374 PCPQNAKCVNNFGSYLCICNPGYKKVNGKCEKLCIRCMNGGSCVENNGCECPKGF----- 1428 Query: 294 SSTTCYDSPQMLLVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWAD 353 S C L+ + +++ ++SL L + VD+D EYIYW + Sbjct: 1429 SGKRCQWYGDASLIFTKGNSVQRMSLPPRPSAIGLLYQSRGHVNVGVDYDCVEEYIYWTE 1488 Query: 354 GLAKTISKARLDGSDQSVVVRSSGV--PDSIAIDPLSRKIYWTDPVMDTINVARLDGSYE 411 + I +A+ DG+ VV+ V P+ IA+D + R IYWTD +D I VA ++GS Sbjct: 1489 IMEGCIMRAKYDGTKLEVVIPRKQVKSPEGIAVDWMGRNIYWTDTGLDVIEVAGMNGSNR 1548 Query: 412 KVIIHTELYDPRAI 425 +V+I L DPRAI Sbjct: 1549 RVLISNALDDPRAI 1562 Score = 81.0 bits (191), Expect = 5e-15 Identities = 50/173 (28%), Positives = 90/173 (52%), Gaps = 12/173 (6%) Query: 572 NGGCSHLCF------NRPDDYICGCPLGLELTADKKTCVEPEAFLVYSRKNIIGRLSIKN 625 NG C LC + ++ C CP G + K+ +A L++++ N + R+S+ Sbjct: 1400 NGKCEKLCIRCMNGGSCVENNGCECPKGF---SGKRCQWYGDASLIFTKGNSVQRMSLPP 1456 Query: 626 EYNDAVIPIKDLKEVSALALYVSGSK-LYWSDSKTKTINRCSVNGSAVEKIV--EWLGLV 682 + + + V+ Y + +YW++ I R +G+ +E ++ + + Sbjct: 1457 RPSAIGLLYQSRGHVNVGVDYDCVEEYIYWTEIMEGCIMRAKYDGTKLEVVIPRKQVKSP 1516 Query: 683 EGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKG 735 EG+A+DW G+NIYWTDT IEV+ ++GS+RR +I L P++I++DP G Sbjct: 1517 EGIAVDWMGRNIYWTDTGLDVIEVAGMNGSNRRVLISNALDDPRAILVDPPNG 1569 Score = 71.7 bits (168), Expect = 3e-12 Identities = 74/307 (24%), Positives = 129/307 (42%), Gaps = 32/307 (10%) Query: 657 SKTKTINRCSV--NGSAVEKIVEWLGLVE-GLAIDWSGQNIYWTDTTTQRIEVSRLDGSS 713 +K ++ R S+ SA+ + + G V G+ D + IYWT+ I ++ DG+ Sbjct: 1444 TKGNSVQRMSLPPRPSAIGLLYQSRGHVNVGVDYDCVEEYIYWTEIMEGCIMRAKYDGTK 1503 Query: 714 RRAII-WQGLKKPKSIVLDPKKGYMYWSELGSKSIKRAAMDGSSVSVFMEQ--------- 763 +I + +K P+ I +D +YW++ G I+ A M+GS+ V + Sbjct: 1504 LEVVIPRKQVKSPEGIAVDWMGRNIYWTDTGLDVIEVAGMNGSNRRVLISNALDDPRAIL 1563 Query: 764 -------VGRVHALAIDYERRAIYWAALDPPVVEFAFLNGTGRQTLADNIPMPYALALFN 816 +G + L + + + + L + + I PY +A FN Sbjct: 1564 VDPPNGDLGLPNGLTLVRANNELCFTDAGTWSIRCVDLGALNVRKVIYPIAYPYGIASFN 1623 Query: 817 DSVYWGDWNTGQIQQA---RKTDGSNRKSIRKDLDYISDLKLYHRA--KSMGSNQCGVDN 871 +++W DW ++Q+ K G K+ I D+K K+ C V+N Sbjct: 1624 RTLFWTDWMNNKVQRIGMDSKDPGVPLKTYVGQSGKIFDVKAVQPCPKKASAKYPCEVNN 1683 Query: 872 GGCSHLCLPTPGDVRTDYRCACPAH-YRLNKDNIT-CSEPEEFLLFAQKNAV-GRIMVAN 928 GGC LCL PG + C+CP H Y + D T C + E L ++ + M+A+ Sbjct: 1684 GGCMGLCLLRPG----GHTCSCPVHMYTVTTDKGTICKDKCEDPLGIEEGIIEDAQMIAS 1739 Query: 929 GECNDAY 935 N+ + Sbjct: 1740 SAWNNNF 1746 Score = 69.7 bits (163), Expect = 1e-11 Identities = 66/241 (27%), Positives = 104/241 (43%), Gaps = 27/241 (11%) Query: 385 DPLSRKIYWTDPVMDTINVARLDGSYEKVII-HTELYDPRAIALHLTAGWMFWSDWNEKK 443 D + IYWT+ + I A+ DG+ +V+I ++ P IA+ ++W+D Sbjct: 1478 DCVEEYIYWTEIMEGCIMRAKYDGTKLEVVIPRKQVKSPEGIAVDWMGRNIYWTDTG--L 1535 Query: 444 PKIERANLDGSGRVLLISEKLTWPNSIALDT---------------VNNKLYWGDARTHK 488 IE A ++GS R +LIS L P +I +D NN+L + DA T Sbjct: 1536 DVIEVAGMNGSNRRVLISNALDDPRAILVDPPNGDLGLPNGLTLVRANNELCFTDAGTWS 1595 Query: 489 IEVCNMDGTE-RKELHSNDIIHIFGXXXXXXXXXXXXMQKRTLDRI---NKNTGLDRQPV 544 I ++ RK ++ I + +G + RI +K+ G+ + Sbjct: 1596 IRCVDLGALNVRKVIYP--IAYPYGIASFNRTLFWTDWMNNKVQRIGMDSKDPGVPLKTY 1653 Query: 545 VEQMANMMGVKAFRL--GAPLGWNPCADDNGGCSHLCFNRPDDYICGCPLGL-ELTADKK 601 V Q + VKA + PC +NGGC LC RP + C CP+ + +T DK Sbjct: 1654 VGQSGKIFDVKAVQPCPKKASAKYPCEVNNGGCMGLCLLRPGGHTCSCPVHMYTVTTDKG 1713 Query: 602 T 602 T Sbjct: 1714 T 1714 Score = 46.0 bits (104), Expect = 2e-04 Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 24/179 (13%) Query: 67 TGIAIDWYTD-KLYWTDGETNKIEVISIVQKYRKV--LFWSEVDLARAIAVVPEDGLMFW 123 +G WY D L +T G N ++ +S+ + + L+ S + + + ++W Sbjct: 1429 SGKRCQWYGDASLIFTKG--NSVQRMSLPPRPSAIGLLYQSRGHVNVGVDYDCVEEYIYW 1486 Query: 124 TDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFN 183 T+ E I RA +G VI R + P GI VD+ IYW D L ++V N Sbjct: 1487 TEIME-GCIMRAKYDGTKL-EVVIPRKQVKSPEGIAVDWMGRNIYWTDTGLDVIEVAGMN 1544 Query: 184 GEKRKRVV---------------KGGLVYPFALTF--SNDKLYWTDWQNWSIYTWDIAA 225 G R+ ++ G L P LT +N++L +TD WSI D+ A Sbjct: 1545 GSNRRVLISNALDDPRAILVDPPNGDLGLPNGLTLVRANNELCFTDAGTWSIRCVDLGA 1603 Score = 35.5 bits (78), Expect = 0.26 Identities = 38/163 (23%), Positives = 62/163 (38%), Gaps = 14/163 (8%) Query: 871 NGGCSHLCLP--TPGDVRTDYRCACPAHYRLNKDNITCS-EPEEFLLFAQKNAVGRIMVA 927 NG C LC+ G + C CP + + C + L+F + N+V R+ + Sbjct: 1400 NGKCEKLCIRCMNGGSCVENNGCECPKGFSGKR----CQWYGDASLIFTKGNSVQRMSLP 1455 Query: 928 -NGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXX 986 G NV ++YD VE+ +YW + I R Sbjct: 1456 PRPSAIGLLYQSRGHVNV-GVDYDCVEEYIYWTEIMEGCIMRAKYD----GTKLEVVIPR 1510 Query: 987 XGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSSTGVIV 1029 + P + +D +GR +YWT D I + N S+ V++ Sbjct: 1511 KQVKSPEGIAVDWMGRNIYWTDTGLDVIEVAGM-NGSNRRVLI 1552 Score = 31.9 bits (69), Expect = 3.2 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 2/92 (2%) Query: 998 DVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIWNDVGRGA 1057 D + +YWT I D VI R P +A R + W D G Sbjct: 1478 DCVEEYIYWTEIMEGCIMRAKYDGTKLEVVIPRKQVKSPEGIAVDWMGRNIYWTDTGLDV 1537 Query: 1058 IMRANVDGTG-RVELARA-DNATALALDQSAG 1087 I A ++G+ RV ++ A D+ A+ +D G Sbjct: 1538 IEVAGMNGSNRRVLISNALDDPRAILVDPPNG 1569 >SB_35244| Best HMM Match : Ldl_recept_b (HMM E-Value=3.2e-11) Length = 534 Score = 67.3 bits (157), Expect = 7e-11 Identities = 47/165 (28%), Positives = 84/165 (50%), Gaps = 24/165 (14%) Query: 645 LYVSGSKLYWSDSKTK-TINRCSVNGSAVEKIVEW-LGLVEGLAIDWSGQNIYWTDTTTQ 702 +++ L+WS+ + I R ++ +V+ IV+ +GLV G+A+DW ++YWTD T + Sbjct: 60 MHMDKQLLFWSELYPEFRIRRMNLTDGSVQTIVDKDIGLVYGIAVDWVNNHLYWTDETYE 119 Query: 703 RIEVSRLDGSSRRAII---WQGLKKP----KSIVLDPKKGYM--------YWSEL--GSK 745 +IEVS LDG++R ++ + G K +SI +D +GY+ +W S Sbjct: 120 KIEVSNLDGTNRLMLLYNKYNGKDKEYAILESIAVDATEGYLFYINWVATFWGTTYDDSP 179 Query: 746 SIKRAAMDGSSVSVFMEQVGRVHA-----LAIDYERRAIYWAALD 785 I R+A+ G E ++ + +DY ++ IY +D Sbjct: 180 HIVRSALSGDESKTIFENYPYSYSHYHIDICLDYAQKRIYTFEID 224 Score = 58.4 bits (135), Expect = 3e-08 Identities = 42/134 (31%), Positives = 65/134 (48%), Gaps = 20/134 (14%) Query: 24 DFHYRKNLICWSDQKPEL-IQCMNYNETYTGEKFKIVSEGLVTPTGIAIDWYTDKLYWTD 82 D H K L+ WS+ PE I+ MN + G IV + + GIA+DW + LYWTD Sbjct: 59 DMHMDKQLLFWSELYPEFRIRRMNLTD---GSVQTIVDKDIGLVYGIAVDWVNNHLYWTD 115 Query: 83 GETNKIEVISIVQKYRKVLFWS-------EVDLARAIAVVPEDGLMFWTDW--------- 126 KIEV ++ R +L ++ E + +IAV +G +F+ +W Sbjct: 116 ETYEKIEVSNLDGTNRLMLLYNKYNGKDKEYAILESIAVDATEGYLFYINWVATFWGTTY 175 Query: 127 GEIPKIERAGMNGD 140 + P I R+ ++GD Sbjct: 176 DDSPHIVRSALSGD 189 Score = 53.2 bits (122), Expect = 1e-06 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Query: 427 LHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDART 486 +H+ +FWS+ + +I R NL ++ + + IA+D VNN LYW D Sbjct: 60 MHMDKQLLFWSELYPEF-RIRRMNLTDGSVQTIVDKDIGLVYGIAVDWVNNHLYWTDETY 118 Query: 487 HKIEVCNMDGTERKELHSN 505 KIEV N+DGT R L N Sbjct: 119 EKIEVSNLDGTNRLMLLYN 137 Score = 50.4 bits (115), Expect = 9e-06 Identities = 30/111 (27%), Positives = 59/111 (53%), Gaps = 9/111 (8%) Query: 338 LTVDFDPKTEYIYWADGLAK-TISKARL-DGSDQSVVVRSSGVPDSIAIDPLSRKIYWTD 395 L+ D + ++W++ + I + L DGS Q++V + G+ IA+D ++ +YWTD Sbjct: 56 LSSDMHMDKQLLFWSELYPEFRIRRMNLTDGSVQTIVDKDIGLVYGIAVDWVNNHLYWTD 115 Query: 396 PVMDTINVARLDGSYEKVIIHT-------ELYDPRAIALHLTAGWMFWSDW 439 + I V+ LDG+ ++++ E +IA+ T G++F+ +W Sbjct: 116 ETYEKIEVSNLDGTNRLMLLYNKYNGKDKEYAILESIAVDATEGYLFYINW 166 Score = 40.7 bits (91), Expect = 0.007 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 2/74 (2%) Query: 734 KGYMYWSELGSK-SIKRAAM-DGSSVSVFMEQVGRVHALAIDYERRAIYWAALDPPVVEF 791 K ++WSEL + I+R + DGS ++ + +G V+ +A+D+ +YW +E Sbjct: 64 KQLLFWSELYPEFRIRRMNLTDGSVQTIVDKDIGLVYGIAVDWVNNHLYWTDETYEKIEV 123 Query: 792 AFLNGTGRQTLADN 805 + L+GT R L N Sbjct: 124 SNLDGTNRLMLLYN 137 Score = 36.7 bits (81), Expect = 0.11 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 2/68 (2%) Query: 120 LMFWTDWGEIPKIERAGMNGDPATRKVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDV 179 L+FW++ P+ MN + + IV +I GI VD+ N+ +YW D + ++V Sbjct: 66 LLFWSEL--YPEFRIRRMNLTDGSVQTIVDKDIGLVYGIAVDWVNNHLYWTDETYEKIEV 123 Query: 180 IDFNGEKR 187 + +G R Sbjct: 124 SNLDGTNR 131 Score = 32.3 bits (70), Expect = 2.4 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 5/75 (6%) Query: 391 IYWTD--PVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKPKIER 448 ++W++ P + DGS + I+ ++ IA+ ++W+D E KIE Sbjct: 67 LFWSELYPEFRIRRMNLTDGSVQ-TIVDKDIGLVYGIAVDWVNNHLYWTD--ETYEKIEV 123 Query: 449 ANLDGSGRVLLISEK 463 +NLDG+ R++L+ K Sbjct: 124 SNLDGTNRLMLLYNK 138 >SB_35533| Best HMM Match : Ldl_recept_b (HMM E-Value=9.8e-05) Length = 909 Score = 64.1 bits (149), Expect = 6e-10 Identities = 38/127 (29%), Positives = 61/127 (48%), Gaps = 4/127 (3%) Query: 610 LVYSRKNIIGRLSIKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKT-KTINRCSVN 668 L +S + I LS+ N + + IK L +ALA+ V L+WS+++ K+ N S Sbjct: 786 LFFSTSSRIKSLSLSNPSSSTTV-IKSLSNANALAIDVKERLLFWSETQAIKSFNLISGQ 844 Query: 669 GSAVEKIVEWLGLVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSI 728 ++ V GLA+DW +Y+TD + I + DG + +I G+ P I Sbjct: 845 TKTIQYRPN--SQVRGLAVDWESSLLYFTDYFYEEIGIVTYDGKRNKTLITAGVANPHGI 902 Query: 729 VLDPKKG 735 +DP G Sbjct: 903 AVDPSSG 909 Score = 46.4 bits (105), Expect = 1e-04 Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Query: 306 LVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLD 365 L + S I +SL +P + T +K L + D K ++W++ A S + Sbjct: 786 LFFSTSSRIKSLSLSNPSSS--TTVIKSLSNANALAIDVKERLLFWSETQAIK-SFNLIS 842 Query: 366 GSDQSVVVRSSGVPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAI 425 G +++ R + +A+D S +Y+TD + I + DG K +I + +P I Sbjct: 843 GQTKTIQYRPNSQVRGLAVDWESSLLYFTDYFYEEIGIVTYDGKRNKTLITAGVANPHGI 902 Query: 426 ALHLTAG 432 A+ ++G Sbjct: 903 AVDPSSG 909 Score = 42.7 bits (96), Expect = 0.002 Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 5/109 (4%) Query: 11 TTIAKDLEQGTAVDFHYRKNLICWSDQKPELIQCMNYNETYTGEKFKIVSEGLVTPTGIA 70 TT+ K L A+ ++ L+ WS+ + I+ N +G+ I G+A Sbjct: 806 TTVIKSLSNANALAIDVKERLLFWSET--QAIKSFNL---ISGQTKTIQYRPNSQVRGLA 860 Query: 71 IDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDG 119 +DW + LY+TD +I +++ K K L + V IAV P G Sbjct: 861 VDWESSLLYFTDYFYEEIGIVTYDGKRNKTLITAGVANPHGIAVDPSSG 909 Score = 42.3 bits (95), Expect = 0.002 Identities = 24/117 (20%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Query: 85 TNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIPKIERAGMNGDPATR 144 +++I+ +S+ + A A+A+ ++ L+FW++ I ++G T+ Sbjct: 791 SSRIKSLSLSNPSSSTTVIKSLSNANALAIDVKERLLFWSETQAIKSFNL--ISGQ--TK 846 Query: 145 KVIVRDNIFWPNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVVKGGLVYPFAL 201 + R N G+ VD+ +SL+Y+ D + + ++ ++G++ K ++ G+ P + Sbjct: 847 TIQYRPNS-QVRGLAVDWESSLLYFTDYFYEEIGIVTYDGKRNKTLITAGVANPHGI 902 >SB_51058| Best HMM Match : EGF (HMM E-Value=0.11) Length = 148 Score = 62.1 bits (144), Expect = 3e-09 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 195 LVYPFALTFSNDKLYWTDWQNWSIYTWDIAANGPKI--KELIKSHPVPADIKVYDESRQI 252 + YP+ + N L+WTDW N + + + P + K + D+K + Sbjct: 43 IAYPYGIASFNRTLFWTDWMNNKVQRIGMDSKDPGVPLKTYVGQSGKIFDVKAVQPCPKK 102 Query: 253 ISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACP 285 SA+ YPC+ NN GC LCLL P G+ C+CP Sbjct: 103 ASAK-YPCEVNNGGCMGLCLLRPG--GHTCSCP 132 Score = 56.4 bits (130), Expect = 1e-07 Identities = 35/106 (33%), Positives = 49/106 (46%), Gaps = 10/106 (9%) Query: 806 IPMPYALALFNDSVYWGDWNTGQIQQA---RKTDGSNRKSIRKDLDYISDLKLYHRA--K 860 I PY +A FN +++W DW ++Q+ K G K+ I D+K K Sbjct: 43 IAYPYGIASFNRTLFWTDWMNNKVQRIGMDSKDPGVPLKTYVGQSGKIFDVKAVQPCPKK 102 Query: 861 SMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAH-YRLNKDNIT 905 + C V+NGGC LCL PG + C+CP H Y + D T Sbjct: 103 ASAKYPCEVNNGGCMGLCLLRPG----GHTCSCPVHMYTVTTDKGT 144 Score = 41.5 bits (93), Expect = 0.004 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%) Query: 534 NKNTGLDRQPVVEQMANMMGVKAFRL--GAPLGWNPCADDNGGCSHLCFNRPDDYICGCP 591 +K+ G+ + V Q + VKA + PC +NGGC LC RP + C CP Sbjct: 73 SKDPGVPLKTYVGQSGKIFDVKAVQPCPKKASAKYPCEVNNGGCMGLCLLRPGGHTCSCP 132 Query: 592 LGL-ELTADKKT 602 + + +T DK T Sbjct: 133 VHMYTVTTDKGT 144 >SB_40455| Best HMM Match : Ldl_recept_b (HMM E-Value=0.019) Length = 122 Score = 57.6 bits (133), Expect = 6e-08 Identities = 28/87 (32%), Positives = 45/87 (51%) Query: 328 TLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQSVVVRSSGVPDSIAIDPL 387 T+ LKD V+ DP + IY+ D + + + + L+GS + G S+A+D + Sbjct: 20 TVSLKDRSNPYAVECDPTDQRIYFTDDIHRRVGRVFLNGSSDETLFTGLGSRHSLALDHV 79 Query: 388 SRKIYWTDPVMDTINVARLDGSYEKVI 414 RK+Y+TD + V LDGS K + Sbjct: 80 GRKVYFTDYFNKNLRVCELDGSNCKTL 106 Score = 51.6 bits (118), Expect = 4e-06 Identities = 25/93 (26%), Positives = 47/93 (50%) Query: 625 NEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEWLGLVEG 684 N + +KD A+ + ++Y++D + + R +NGS+ E + LG Sbjct: 14 NSNEQTTVSLKDRSNPYAVECDPTDQRIYFTDDIHRRVGRVFLNGSSDETLFTGLGSRHS 73 Query: 685 LAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAI 717 LA+D G+ +Y+TD + + V LDGS+ + + Sbjct: 74 LALDHVGRKVYFTDYFNKNLRVCELDGSNCKTL 106 Score = 38.3 bits (85), Expect = 0.037 Identities = 20/84 (23%), Positives = 42/84 (50%) Query: 725 PKSIVLDPKKGYMYWSELGSKSIKRAAMDGSSVSVFMEQVGRVHALAIDYERRAIYWAAL 784 P ++ DP +Y+++ + + R ++GSS +G H+LA+D+ R +Y+ Sbjct: 29 PYAVECDPTDQRIYFTDDIHRRVGRVFLNGSSDETLFTGLGSRHSLALDHVGRKVYFTDY 88 Query: 785 DPPVVEFAFLNGTGRQTLADNIPM 808 + L+G+ +TL N+ + Sbjct: 89 FNKNLRVCELDGSNCKTLKTNVAL 112 Score = 36.3 bits (80), Expect = 0.15 Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 6/97 (6%) Query: 927 ANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXX 986 AN + L N A+E DP ++++Y+ DD + RV ++ Sbjct: 12 ANNSNEQTTVSLKDRSNPYAVECDPTDQRIYFTDDIHRRVGRVFLN------GSSDETLF 65 Query: 987 XGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNS 1023 GL + + LD +GR +Y+T ++ +D ++ Sbjct: 66 TGLGSRHSLALDHVGRKVYFTDYFNKNLRVCELDGSN 102 Score = 36.3 bits (80), Expect = 0.15 Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 1/61 (1%) Query: 445 KIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERKELHS 504 ++ R L+GS L + L +S+ALD V K+Y+ D + VC +DG+ K L + Sbjct: 50 RVGRVFLNGSSDETLFTG-LGSRHSLALDHVGRKVYFTDYFNKNLRVCELDGSNCKTLKT 108 Query: 505 N 505 N Sbjct: 109 N 109 >SB_5725| Best HMM Match : Ldl_recept_b (HMM E-Value=0.019) Length = 409 Score = 57.6 bits (133), Expect = 6e-08 Identities = 28/87 (32%), Positives = 45/87 (51%) Query: 328 TLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQSVVVRSSGVPDSIAIDPL 387 T+ LKD V+ DP + IY+ D + + + + L+GS + G S+A+D + Sbjct: 170 TVSLKDRSNPYAVECDPTDQRIYFTDDIHRRVGRVFLNGSSDETLFTGLGSRHSLALDHV 229 Query: 388 SRKIYWTDPVMDTINVARLDGSYEKVI 414 RK+Y+TD + V LDGS K + Sbjct: 230 GRKVYFTDYFNKNLRVCELDGSNCKTL 256 Score = 51.6 bits (118), Expect = 4e-06 Identities = 25/93 (26%), Positives = 47/93 (50%) Query: 625 NEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEWLGLVEG 684 N + +KD A+ + ++Y++D + + R +NGS+ E + LG Sbjct: 164 NSNEQTTVSLKDRSNPYAVECDPTDQRIYFTDDIHRRVGRVFLNGSSDETLFTGLGSRHS 223 Query: 685 LAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAI 717 LA+D G+ +Y+TD + + V LDGS+ + + Sbjct: 224 LALDHVGRKVYFTDYFNKNLRVCELDGSNCKTL 256 Score = 41.5 bits (93), Expect = 0.004 Identities = 31/109 (28%), Positives = 57/109 (52%), Gaps = 8/109 (7%) Query: 349 IYWADGLAKT-ISKARLDGSDQSVVV--RSSGVPDSIAIDPLSRKIYWTDPVMDTINVAR 405 +Y+ G +T I K+ +DGS+ VV+ R++ P +A+D + ++YW+ + +I+ Sbjct: 1 MYFTAGYVQTAIYKSHMDGSNMQVVMTLRNNSEPWGLALDRANNRLYWSTKIDRSIHY-- 58 Query: 406 LDGSYEKVIIH--TELYDPRAIALHLTAGWMFWSDWNEKK-PKIERANL 451 LD S I H T + + ++ G++ W D N ++ RANL Sbjct: 59 LDLSLSSPIDHKLTSNHVVDPFRMVVSKGYLHWIDLNAANWGEVYRANL 107 Score = 38.3 bits (85), Expect = 0.037 Identities = 20/84 (23%), Positives = 42/84 (50%) Query: 725 PKSIVLDPKKGYMYWSELGSKSIKRAAMDGSSVSVFMEQVGRVHALAIDYERRAIYWAAL 784 P ++ DP +Y+++ + + R ++GSS +G H+LA+D+ R +Y+ Sbjct: 179 PYAVECDPTDQRIYFTDDIHRRVGRVFLNGSSDETLFTGLGSRHSLALDHVGRKVYFTDY 238 Query: 785 DPPVVEFAFLNGTGRQTLADNIPM 808 + L+G+ +TL N+ + Sbjct: 239 FNKNLRVCELDGSNCKTLKTNVAL 262 Score = 36.3 bits (80), Expect = 0.15 Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 6/97 (6%) Query: 927 ANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXX 986 AN + L N A+E DP ++++Y+ DD + RV ++ Sbjct: 162 ANNSNEQTTVSLKDRSNPYAVECDPTDQRIYFTDDIHRRVGRVFLN------GSSDETLF 215 Query: 987 XGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNS 1023 GL + + LD +GR +Y+T ++ +D ++ Sbjct: 216 TGLGSRHSLALDHVGRKVYFTDYFNKNLRVCELDGSN 252 Score = 36.3 bits (80), Expect = 0.15 Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 1/61 (1%) Query: 445 KIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERKELHS 504 ++ R L+GS L + L +S+ALD V K+Y+ D + VC +DG+ K L + Sbjct: 200 RVGRVFLNGSSDETLFTG-LGSRHSLALDHVGRKVYFTDYFNKNLRVCELDGSNCKTLKT 258 Query: 505 N 505 N Sbjct: 259 N 259 Score = 33.5 bits (73), Expect = 1.0 Identities = 21/70 (30%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 446 IERANLDGSG-RVLLISEKLTWPNSIALDTVNNKLYWG---DARTHKIEVCNMDGTERKE 501 I ++++DGS +V++ + P +ALD NN+LYW D H +++ + K Sbjct: 12 IYKSHMDGSNMQVVMTLRNNSEPWGLALDRANNRLYWSTKIDRSIHYLDLSLSSPIDHK- 70 Query: 502 LHSNDIIHIF 511 L SN ++ F Sbjct: 71 LTSNHVVDPF 80 >SB_20981| Best HMM Match : Ldl_recept_b (HMM E-Value=0.037) Length = 206 Score = 56.4 bits (130), Expect = 1e-07 Identities = 30/111 (27%), Positives = 57/111 (51%), Gaps = 2/111 (1%) Query: 625 NEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEWLGLVEG 684 N + +KD A+ + ++Y++D + + R +NGS+ E + LG V Sbjct: 39 NSNEQTTVSLKDRSNPFAVECDPTDQRIYFTDDIHRRLGRVFLNGSSDETLFTGLGSVHN 98 Query: 685 LAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKG 735 LA+D G+ +Y+TD + + V LDG++ + + + + P S+ +D K G Sbjct: 99 LALDHVGRKVYFTDYNSGGLWVCELDGTNAKKL--KTMDYPSSLEVDSKNG 147 Score = 52.8 bits (121), Expect = 2e-06 Identities = 26/85 (30%), Positives = 44/85 (51%) Query: 328 TLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQSVVVRSSGVPDSIAIDPL 387 T+ LKD V+ DP + IY+ D + + + + L+GS + G ++A+D + Sbjct: 45 TVSLKDRSNPFAVECDPTDQRIYFTDDIHRRLGRVFLNGSSDETLFTGLGSVHNLALDHV 104 Query: 388 SRKIYWTDPVMDTINVARLDGSYEK 412 RK+Y+TD + V LDG+ K Sbjct: 105 GRKVYFTDYNSGGLWVCELDGTNAK 129 Score = 36.7 bits (81), Expect = 0.11 Identities = 31/134 (23%), Positives = 62/134 (46%), Gaps = 9/134 (6%) Query: 347 EYIYWADGLAKTIS----KARLDGSDQSVVVRSSGVPDSIAIDPLSRKIYWTDPVMDTIN 402 +YI AD + I A +V ++ P ++ DP ++IY+TD + + Sbjct: 18 DYIIVADNFSPRILAVPWNANNSNEQTTVSLKDRSNPFAVECDPTDQRIYFTDDIHRRLG 77 Query: 403 VARLDGSYEKVIIHTELYDPRAIALHLTAGWMFWSDWNEKKPKIERANLDGSGRVLLISE 462 L+GS ++ + T L +AL ++++D+N + LDG+ L + Sbjct: 78 RVFLNGSSDETLF-TGLGSVHNLALDHVGRKVYFTDYNSGGLWV--CELDGTNAKKL--K 132 Query: 463 KLTWPNSIALDTVN 476 + +P+S+ +D+ N Sbjct: 133 TMDYPSSLEVDSKN 146 Score = 36.3 bits (80), Expect = 0.15 Identities = 20/78 (25%), Positives = 39/78 (50%) Query: 725 PKSIVLDPKKGYMYWSELGSKSIKRAAMDGSSVSVFMEQVGRVHALAIDYERRAIYWAAL 784 P ++ DP +Y+++ + + R ++GSS +G VH LA+D+ R +Y+ Sbjct: 54 PFAVECDPTDQRIYFTDDIHRRLGRVFLNGSSDETLFTGLGSVHNLALDHVGRKVYFTDY 113 Query: 785 DPPVVEFAFLNGTGRQTL 802 + + L+GT + L Sbjct: 114 NSGGLWVCELDGTNAKKL 131 Score = 36.3 bits (80), Expect = 0.15 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Query: 445 KIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERKELHS 504 ++ R L+GS L + L +++ALD V K+Y+ D + + VC +DGT K+L + Sbjct: 75 RLGRVFLNGSSDETLFTG-LGSVHNLALDHVGRKVYFTDYNSGGLWVCELDGTNAKKLKT 133 Query: 505 ND 506 D Sbjct: 134 MD 135 Score = 35.5 bits (78), Expect = 0.26 Identities = 22/98 (22%), Positives = 43/98 (43%), Gaps = 6/98 (6%) Query: 927 ANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIRRVPISYXXXXXXXXXXXXX 986 AN + L N A+E DP ++++Y+ DD + RV ++ Sbjct: 37 ANNSNEQTTVSLKDRSNPFAVECDPTDQRIYFTDDIHRRLGRVFLN------GSSDETLF 90 Query: 987 XGLSRPYHMVLDVLGRTMYWTCADRDSINATSIDNNSS 1024 GL +++ LD +GR +Y+T + + +D ++ Sbjct: 91 TGLGSVHNLALDHVGRKVYFTDYNSGGLWVCELDGTNA 128 Score = 31.5 bits (68), Expect = 4.2 Identities = 22/96 (22%), Positives = 43/96 (44%), Gaps = 2/96 (2%) Query: 155 PNGITVDYNNSLIYWVDAKLQFVDVIDFNGEKRKRVVKG-GLVYPFALTFSNDKLYWTDW 213 P + D + IY+ D + + + NG + + G G V+ AL K+Y+TD+ Sbjct: 54 PFAVECDPTDQRIYFTDDIHRRLGRVFLNGSSDETLFTGLGSVHNLALDHVGRKVYFTDY 113 Query: 214 QNWSIYTWDI-AANGPKIKELIKSHPVPADIKVYDE 248 + ++ ++ N K+K + + D K D+ Sbjct: 114 NSGGLWVCELDGTNAKKLKTMDYPSSLEVDSKNGDD 149 >SB_40871| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 279 Score = 53.2 bits (122), Expect = 1e-06 Identities = 31/101 (30%), Positives = 37/101 (36%), Gaps = 14/101 (13%) Query: 1096 QCDGQQDCEDGRDEAECGAC-GGDVRCADGTXXX-------------XXXXXXXXXXXXX 1141 +CDG+ DC DG DE CG+C RC +G Sbjct: 99 RCDGENDCRDGSDETGCGSCSSSQFRCRNGRCVSRSWVCDKDNDCGDGSDEVQCNRAGGG 158 Query: 1142 XXXXDAFRCDEGLCIAARFVCDGRPQCADGSDEAPAACAYG 1182 +RCD CI +VCD C DGSDE YG Sbjct: 159 WCGAGRYRCDNDRCIPRNWVCDRDNDCGDGSDETGCRGVYG 199 >SB_54289| Best HMM Match : EGF (HMM E-Value=9.2e-05) Length = 109 Score = 53.2 bits (122), Expect = 1e-06 Identities = 23/44 (52%), Positives = 27/44 (61%), Gaps = 3/44 (6%) Query: 863 GSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 GS+ C DNG CSH+CLP D +T CACP LN D +TC Sbjct: 13 GSSPCTADNGNCSHICLP---DSKTTKVCACPTGAPLNADGLTC 53 Score = 47.2 bits (107), Expect = 8e-05 Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 564 GWNPCADDNGGCSHLCF-NRPDDYICGCPLGLELTADKKTC 603 G +PC DNG CSH+C + +C CP G L AD TC Sbjct: 13 GSSPCTADNGNCSHICLPDSKTTKVCACPTGAPLNADGLTC 53 Score = 39.5 bits (88), Expect = 0.016 Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 4/52 (7%) Query: 259 PCKKNNAGCSHLCLLSPDPPGYN-CACPTGVKLRENSSTTCYDSPQMLLVVA 309 PC +N CSH+CL PD CACPTG L + TC + LV A Sbjct: 16 PCTADNGNCSHICL--PDSKTTKVCACPTGAPLNAD-GLTCGSDVTVYLVNA 64 >SB_41134| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 802 Score = 52.8 bits (121), Expect = 2e-06 Identities = 31/83 (37%), Positives = 42/83 (50%), Gaps = 5/83 (6%) Query: 530 LDRINKNTGLDRQPVVEQMANMMGVKA-FRLGAPLGWNPCADDNGGCSHLCFNRPDDYIC 588 L R + N L R V +Q + G +A FR NPC +NGGC +C N P+ IC Sbjct: 87 LQRSSSNQMLVRF-VADQSISKTGFRATFRAELQATGNPCITNNGGCGQVCLNTPNGRIC 145 Query: 589 GCPLGLELTADKKTCVEPEAFLV 611 C G L D+++C AFL+ Sbjct: 146 SCHHGYTLEFDEESC---RAFLI 165 Score = 47.6 bits (108), Expect = 6e-05 Identities = 17/37 (45%), Positives = 22/37 (59%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCV 604 C ++NGGC LC N P ++C C G L D KTC+ Sbjct: 272 CQNNNGGCRDLCINTPGSFMCQCRQGYVLANDNKTCI 308 Score = 40.3 bits (90), Expect = 0.009 Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 4/42 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 ++C +NGGC LC+ TPG + C C Y L DN TC Sbjct: 270 DECQNNNGGCRDLCINTPG----SFMCQCRQGYVLANDNKTC 307 Score = 37.1 bits (82), Expect = 0.085 Identities = 14/30 (46%), Positives = 15/30 (50%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELT 597 C D+NGGC LC N Y C C G T Sbjct: 386 CMDNNGGCGQLCVNTAGSYHCKCEPGYNAT 415 Score = 35.9 bits (79), Expect = 0.20 Identities = 12/23 (52%), Positives = 14/23 (60%) Query: 568 CADDNGGCSHLCFNRPDDYICGC 590 CA DNGGC C N P ++ C C Sbjct: 608 CAVDNGGCHQKCVNSPGNFSCAC 630 Score = 35.1 bits (77), Expect = 0.34 Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 4/33 (12%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHY 897 ++C VDNGGC C+ +PG ++ CAC Y Sbjct: 606 DECAVDNGGCHQKCVNSPG----NFSCACHDGY 634 Score = 35.1 bits (77), Expect = 0.34 Identities = 14/34 (41%), Positives = 17/34 (50%) Query: 575 CSHLCFNRPDDYICGCPLGLELTADKKTCVEPEA 608 C C N Y C CP G +LT DK+ C +A Sbjct: 755 CEKECVNTEGSYFCFCPPGYQLTDDKRHCQGDQA 788 Score = 34.7 bits (76), Expect = 0.45 Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 4/38 (10%) Query: 874 CSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 C H+C + + + C C Y LN D ITCS+ +E Sbjct: 716 CQHIC----NNTQASFHCECREGYILNSDGITCSDIDE 749 Score = 33.5 bits (73), Expect = 1.0 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 2/41 (4%) Query: 250 RQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKL 290 R + A PC NN GC +CL +P+ G C+C G L Sbjct: 115 RAELQATGNPCITNNGGCGQVCLNTPN--GRICSCHHGYTL 153 Score = 33.1 bits (72), Expect = 1.4 Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 4/42 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 N C +NGGC +CL TP C+C Y L D +C Sbjct: 123 NPCITNNGGCGQVCLNTP----NGRICSCHHGYTLEFDEESC 160 Score = 33.1 bits (72), Expect = 1.4 Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 4/40 (10%) Query: 872 GGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 G C H C T G ++C+C Y L D +TC + +E Sbjct: 572 GDCDHKCNNTAGS----FKCSCHHGYALTDDGLTCQDIDE 607 Score = 32.7 bits (71), Expect = 1.8 Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 3/39 (7%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTC 298 C+ NN GC LC+ +P + C C G L N + TC Sbjct: 272 CQNNNGGCRDLCINTPG--SFMCQCRQGYVL-ANDNKTC 307 Score = 32.3 bits (70), Expect = 2.4 Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 4/41 (9%) Query: 857 HRAKSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHY 897 +R + ++C +NGGC LC+ T G Y C C Y Sbjct: 376 NRTRCQDIDECMDNNGGCGQLCVNTAG----SYHCKCEPGY 412 Score = 31.9 bits (69), Expect = 3.2 Identities = 13/31 (41%), Positives = 14/31 (45%) Query: 573 GGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 G C H C N + C C G LT D TC Sbjct: 572 GDCDHKCNNTAGSFKCSCHHGYALTDDGLTC 602 Score = 30.7 bits (66), Expect = 7.4 Identities = 12/39 (30%), Positives = 17/39 (43%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCV 604 N CA C LC + Y C C G ++ D +C+ Sbjct: 311 NECATRKHRCEQLCRDTDGGYYCECHKGYQVGPDGMSCI 349 Score = 30.3 bits (65), Expect = 9.8 Identities = 14/37 (37%), Positives = 17/37 (45%), Gaps = 1/37 (2%) Query: 568 CADDN-GGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 CAD C H+C N + C C G L +D TC Sbjct: 708 CADPQVNKCQHICNNTQASFHCECREGYILNSDGITC 744 >SB_29649| Best HMM Match : Sushi (HMM E-Value=4.1e-18) Length = 214 Score = 52.8 bits (121), Expect = 2e-06 Identities = 20/40 (50%), Positives = 25/40 (62%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 N C+ DNGGCSH C N C CP G+ LT ++TCV+ Sbjct: 3 NECSTDNGGCSHSCHNTAGGVKCSCPGGMALTKGQRTCVD 42 Score = 46.8 bits (106), Expect = 1e-04 Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 4/47 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 N+C DNGGCSH C T G V +C+CP L K TC + E Sbjct: 3 NECSTDNGGCSHSCHNTAGGV----KCSCPGGMALTKGQRTCVDVNE 45 Score = 40.3 bits (90), Expect = 0.009 Identities = 14/38 (36%), Positives = 20/38 (52%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N CA +NGGC H C N + C C G + ++ + C Sbjct: 44 NECAKNNGGCQHTCVNTHRSFKCLCNRGFSMNSNGRNC 81 Score = 35.9 bits (79), Expect = 0.20 Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 4/42 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 N+C +NGGC H C+ T ++C C + +N + C Sbjct: 44 NECAKNNGGCQHTCVNT----HRSFKCLCNRGFSMNSNGRNC 81 Score = 34.3 bits (75), Expect = 0.60 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 3/41 (7%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYD 300 C +N GCSH C G C+CP G+ L + TC D Sbjct: 5 CSTDNGGCSHSC--HNTAGGVKCSCPGGMALTK-GQRTCVD 42 Score = 33.1 bits (72), Expect = 1.4 Identities = 17/60 (28%), Positives = 24/60 (40%), Gaps = 2/60 (3%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQMLLVVAQRSTISKISL 319 C KNN GC H C+ + + C C G + N +L + T+ ISL Sbjct: 46 CAKNNGGCQHTCVNT--HRSFKCLCNRGFSMNSNGRNCDRMYDLKVLKYGPQDTLPSISL 103 >SB_23898| Best HMM Match : Ldl_recept_a (HMM E-Value=1.4013e-45) Length = 291 Score = 52.0 bits (119), Expect = 3e-06 Identities = 32/101 (31%), Positives = 37/101 (36%), Gaps = 14/101 (13%) Query: 1096 QCDGQQDCEDGRDEAECGACGG-DVRCADGTXXXXXXXXXXXXXXXXXXXXDA------- 1147 +CDG DC DG DE CG CG RC +G A Sbjct: 115 KCDGSNDCRDGTDEVGCGKCGSTQFRCRNGNCINRNYVCDKDNDCGDGSDEVACSRLNGG 174 Query: 1148 ------FRCDEGLCIAARFVCDGRPQCADGSDEAPAACAYG 1182 +RCD CI +VCD C D SDE+ YG Sbjct: 175 WCGAGQYRCDNDRCIPLNWVCDRLNDCHDNSDESGCRGVYG 215 Score = 35.9 bits (79), Expect = 0.20 Identities = 12/27 (44%), Positives = 17/27 (62%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 F+C+ G C+ + CDG C DG+DE Sbjct: 102 FKCNNGHCVHRNWKCDGSNDCRDGTDE 128 >SB_3317| Best HMM Match : EGF (HMM E-Value=1e-06) Length = 67 Score = 50.8 bits (116), Expect = 6e-06 Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 2/40 (5%) Query: 566 NPCADDNGGCSHLCF--NRPDDYICGCPLGLELTADKKTC 603 N C D+NGGCSHLC P + C CP G+ +++D KTC Sbjct: 3 NRCGDNNGGCSHLCLLAAAPRKFSCKCPNGMNMSSDGKTC 42 Score = 48.8 bits (111), Expect = 3e-05 Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSP 302 C NN GCSHLCLL+ P ++C CP G+ + + TC P Sbjct: 5 CGDNNGGCSHLCLLAAAPRKFSCKCPNGMNM-SSDGKTCTGQP 46 Score = 44.0 bits (99), Expect = 7e-04 Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 2/43 (4%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCS 907 N+CG +NGGCSHLCL + + C CP ++ D TC+ Sbjct: 3 NRCGDNNGGCSHLCLLAAAPRK--FSCKCPNGMNMSSDGKTCT 43 >SB_12366| Best HMM Match : SRCR (HMM E-Value=4.4e-33) Length = 457 Score = 50.8 bits (116), Expect = 6e-06 Identities = 22/43 (51%), Positives = 26/43 (60%), Gaps = 3/43 (6%) Query: 864 SNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 S+ C DNG CSH+CLP D +T CACP LN D +TC Sbjct: 2 SSPCTADNGNCSHICLP---DSKTTKVCACPTGAPLNADGLTC 41 Score = 48.0 bits (109), Expect = 5e-05 Identities = 35/107 (32%), Positives = 56/107 (52%), Gaps = 8/107 (7%) Query: 329 LPLK-DLKRTLTVDFDPKTEYIY-WADGLAKTISKARL-DGSDQSVVVRSSGVPDSIAID 385 +P+K +R V DP ++ IY W I K L G D+ ++ V +AID Sbjct: 259 IPIKIHNRRPEGVAIDPASKDIYYWTSNY--DIRKVSLRTGKDEFILANQRRVT-GMAID 315 Query: 386 PLSRKIYWTDPVMDTINVARLDGSYEKVIIHTELYDPRAIALHLTAG 432 P +K+YW+D + I A+LDG+Y ++ + +PRAI ++AG Sbjct: 316 PGCQKMYWSDYEKNRILAAKLDGTYMTKVV--SVVNPRAIVTDISAG 360 Score = 46.0 bits (104), Expect = 2e-04 Identities = 18/39 (46%), Positives = 22/39 (56%), Gaps = 1/39 (2%) Query: 566 NPCADDNGGCSHLCF-NRPDDYICGCPLGLELTADKKTC 603 +PC DNG CSH+C + +C CP G L AD TC Sbjct: 3 SPCTADNGNCSHICLPDSKTTKVCACPTGAPLNADGLTC 41 Score = 42.7 bits (96), Expect = 0.002 Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 6/134 (4%) Query: 605 EPEAFLVYSR--KNIIGRLSIKNEYNDAVIPIK-DLKEVSALALYVSGSKLYWSDSKTKT 661 + +AF+V + +N++ ++ ++ + IPIK + +A+ + +Y+ S Sbjct: 230 DADAFMVVTDTGRNLLQQVIFESNSHIRQIPIKIHNRRPEGVAIDPASKDIYYWTSNYD- 288 Query: 662 INRCSVNGSAVEKIVEWLGLVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQG 721 I + S+ E I+ V G+AID Q +YW+D RI ++LDG+ ++ Sbjct: 289 IRKVSLRTGKDEFILANQRRVTGMAIDPGCQKMYWSDYEKNRILAAKLDGTYMTKVV--S 346 Query: 722 LKKPKSIVLDPKKG 735 + P++IV D G Sbjct: 347 VVNPRAIVTDISAG 360 Score = 38.7 bits (86), Expect = 0.028 Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 3/39 (7%) Query: 259 PCKKNNAGCSHLCLLSPDPPGYN-CACPTGVKLRENSST 296 PC +N CSH+CL PD CACPTG L + T Sbjct: 4 PCTADNGNCSHICL--PDSKTTKVCACPTGAPLNADGLT 40 Score = 35.1 bits (77), Expect = 0.34 Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 4/74 (5%) Query: 683 EGLAIDWSGQNIY-WTDTTTQRIEVSRLDGSSRRAIIWQGLKKPKSIVLDPKKGYMYWSE 741 EG+AID + ++IY WT R +VS G I ++ + +DP MYWS+ Sbjct: 269 EGVAIDPASKDIYYWTSNYDIR-KVSLRTGKDE--FILANQRRVTGMAIDPGCQKMYWSD 325 Query: 742 LGSKSIKRAAMDGS 755 I A +DG+ Sbjct: 326 YEKNRILAAKLDGT 339 Score = 33.5 bits (73), Expect = 1.0 Identities = 22/97 (22%), Positives = 43/97 (44%), Gaps = 3/97 (3%) Query: 991 RPYHMVLDVLGRTMYWTCADRDSINATSIDNNSSTGVIVRGDRMLPRHLAFHQTKRYLIW 1050 RP + +D + +Y+ ++ D I S+ ++ R+ +A + + W Sbjct: 267 RPEGVAIDPASKDIYYWTSNYD-IRKVSLRTGKDEFILANQRRVTG--MAIDPGCQKMYW 323 Query: 1051 NDVGRGAIMRANVDGTGRVELARADNATALALDQSAG 1087 +D + I+ A +DGT ++ N A+ D SAG Sbjct: 324 SDYEKNRILAAKLDGTYMTKVVSVVNPRAIVTDISAG 360 Score = 31.9 bits (69), Expect = 3.2 Identities = 18/76 (23%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Query: 723 KKPKSIVLDP-KKGYMYWSELGSKSIKRAAMDGSSVSVFMEQVGRVHALAIDYERRAIYW 781 ++P+ + +DP K YW+ + I++ ++ + RV +AID + +YW Sbjct: 266 RRPEGVAIDPASKDIYYWTS--NYDIRKVSLRTGKDEFILANQRRVTGMAIDPGCQKMYW 323 Query: 782 AALDPPVVEFAFLNGT 797 + + + A L+GT Sbjct: 324 SDYEKNRILAAKLDGT 339 >SB_37830| Best HMM Match : Peptidase_C54 (HMM E-Value=3.3e-11) Length = 878 Score = 50.4 bits (115), Expect = 9e-06 Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 2/62 (3%) Query: 306 LVVAQRSTISKISLDSPDFTPYTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLD 365 L+ AQR++I +++L D TLPL L+ + +DFD + +YWAD A TI ++ L+ Sbjct: 818 LLYAQRTSIRRVTLG--DHLESTLPLSGLRNAIALDFDYRENCVYWADITADTIQRSFLN 875 Query: 366 GS 367 GS Sbjct: 876 GS 877 Score = 47.6 bits (108), Expect = 6e-05 Identities = 23/67 (34%), Positives = 44/67 (65%), Gaps = 4/67 (5%) Query: 904 ITCSEPE--EFLLFAQKNAVGRIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDD 961 I+C P +FLL+AQ+ ++ R+ + G+ ++ +PL+GL+N A+++D E +YW D Sbjct: 807 ISCPVPSLLQFLLYAQRTSIRRVTL--GDHLESTLPLSGLRNAIALDFDYRENCVYWADI 864 Query: 962 DSHSIRR 968 + +I+R Sbjct: 865 TADTIQR 871 Score = 39.9 bits (89), Expect = 0.012 Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 5/85 (5%) Query: 590 CPLGLE--LTADKKTCVEPEA--FLVYSRKNIIGRLSIKNEYNDAVIPIKDLKEVSALAL 645 C GLE K +C P FL+Y+++ I R+++ ++ ++ +P+ L+ AL Sbjct: 794 CEKGLEDVYAPYKISCPVPSLLQFLLYAQRTSIRRVTL-GDHLESTLPLSGLRNAIALDF 852 Query: 646 YVSGSKLYWSDSKTKTINRCSVNGS 670 + +YW+D TI R +NGS Sbjct: 853 DYRENCVYWADITADTIQRSFLNGS 877 Score = 31.5 bits (68), Expect = 4.2 Identities = 16/54 (29%), Positives = 31/54 (57%), Gaps = 3/54 (5%) Query: 746 SIKRAAMDGSSVSVFMEQVGRVHALAIDYERR--AIYWAALDPPVVEFAFLNGT 797 SI+R + G + + G +A+A+D++ R +YWA + ++ +FLNG+ Sbjct: 825 SIRRVTL-GDHLESTLPLSGLRNAIALDFDYRENCVYWADITADTIQRSFLNGS 877 >SB_59093| Best HMM Match : Ldl_recept_b (HMM E-Value=8.1e-06) Length = 69 Score = 49.6 bits (113), Expect = 1e-05 Identities = 20/37 (54%), Positives = 28/37 (75%) Query: 679 LGLVEGLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRR 715 +G+V G+A+D IYWTD T ++IEVS LDG++RR Sbjct: 2 MGMVYGIAVDCVNDKIYWTDETYEKIEVSNLDGTNRR 38 Score = 44.0 bits (99), Expect = 7e-04 Identities = 18/31 (58%), Positives = 23/31 (74%) Query: 470 IALDTVNNKLYWGDARTHKIEVCNMDGTERK 500 IA+D VN+K+YW D KIEV N+DGT R+ Sbjct: 8 IAVDCVNDKIYWTDETYEKIEVSNLDGTNRR 38 Score = 37.1 bits (82), Expect = 0.085 Identities = 15/42 (35%), Positives = 27/42 (64%) Query: 377 GVPDSIAIDPLSRKIYWTDPVMDTINVARLDGSYEKVIIHTE 418 G+ IA+D ++ KIYWTD + I V+ LDG+ ++ ++ + Sbjct: 3 GMVYGIAVDCVNDKIYWTDETYEKIEVSNLDGTNRRMQLYNK 44 Score = 36.7 bits (81), Expect = 0.11 Identities = 16/40 (40%), Positives = 25/40 (62%) Query: 68 GIAIDWYTDKLYWTDGETNKIEVISIVQKYRKVLFWSEVD 107 GIA+D DK+YWTD KIEV ++ R++ +++ D Sbjct: 7 GIAVDCVNDKIYWTDETYEKIEVSNLDGTNRRMQLYNKND 46 Score = 30.3 bits (65), Expect = 9.8 Identities = 11/19 (57%), Positives = 14/19 (73%) Query: 194 GLVYPFALTFSNDKLYWTD 212 G+VY A+ NDK+YWTD Sbjct: 3 GMVYGIAVDCVNDKIYWTD 21 >SB_53569| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 921 Score = 48.0 bits (109), Expect = 5e-05 Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 9/87 (10%) Query: 825 NTGQIQQARKTDGSNRKSIRKDLDYISDLKLYHRAKSMGSNQCGVDNGGCSHLCLPTPGD 884 N G Q T GS R + +SD K ++C ++ GGCSH C T G Sbjct: 362 NGGCSQLCLNTQGSYRCACDYGYRLLSDGKT-----CQDIDECAINKGGCSHTCQNTAGG 416 Query: 885 VRTDYRCACPAHYRLNKDNITCSEPEE 911 Y+C CP Y + +DN TC + E Sbjct: 417 ----YQCQCPRGYIMQQDNKTCEDINE 439 Score = 46.8 bits (106), Expect = 1e-04 Identities = 22/43 (51%), Positives = 26/43 (60%), Gaps = 4/43 (9%) Query: 869 VDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 ++NGGCS LCL T G YRCAC YRL D TC + +E Sbjct: 360 LNNGGCSQLCLNTQGS----YRCACDYGYRLLSDGKTCQDIDE 398 Score = 45.6 bits (103), Expect = 2e-04 Identities = 18/36 (50%), Positives = 20/36 (55%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 CA + GGCSH C N Y C CP G + D KTC Sbjct: 399 CAINKGGCSHTCQNTAGGYQCQCPRGYIMQQDNKTC 434 Score = 44.4 bits (100), Expect = 6e-04 Identities = 17/33 (51%), Positives = 19/33 (57%) Query: 571 DNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 +NGGCS LC N Y C C G L +D KTC Sbjct: 361 NNGGCSQLCLNTQGSYRCACDYGYRLLSDGKTC 393 Score = 41.1 bits (92), Expect = 0.005 Identities = 16/45 (35%), Positives = 24/45 (53%) Query: 867 CGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 C ++NGGC+H+C +C C A Y L+ DN C + +E Sbjct: 272 CKLNNGGCAHICAERTIRGHVITKCQCRAGYHLHSDNKQCIDDDE 316 Score = 41.1 bits (92), Expect = 0.005 Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE-PEAFLV 611 C++ N C H+C N P Y C C G L D+++C + E FL+ Sbjct: 317 CSNPNR-CDHVCINNPGSYACACHKGFFLKLDERSCADLDECFLL 360 Score = 38.3 bits (85), Expect = 0.037 Identities = 15/26 (57%), Positives = 17/26 (65%) Query: 1149 RCDEGLCIAARFVCDGRPQCADGSDE 1174 RCD G C R+ CDG+ C DGSDE Sbjct: 230 RCDNGRCEDKRWWCDGQDDCNDGSDE 255 Score = 37.9 bits (84), Expect = 0.049 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 5/48 (10%) Query: 865 NQCGVDNGGC-SHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 N+C V NGGC H C+ T G Y+C C YRL+ C + +E Sbjct: 520 NECEVQNGGCGKHTCINTYG----SYKCQCLDGYRLDARTEQCVDIDE 563 Score = 36.3 bits (80), Expect = 0.15 Identities = 17/41 (41%), Positives = 19/41 (46%), Gaps = 1/41 (2%) Query: 566 NPCADDNGGCS-HLCFNRPDDYICGCPLGLELTADKKTCVE 605 N C NGGC H C N Y C C G L A + CV+ Sbjct: 520 NECEVQNGGCGKHTCINTYGSYKCQCLDGYRLDARTEQCVD 560 Score = 35.9 bits (79), Expect = 0.20 Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 3/41 (7%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYD 300 C N GCSH C + GY C CP G +++++ TC D Sbjct: 399 CAINKGGCSHTCQNTAG--GYQCQCPRGYIMQQDNK-TCED 436 Score = 35.1 bits (77), Expect = 0.34 Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 4/50 (8%) Query: 562 PLGWNPCADDNGGCSHLCFNRP-DDYI---CGCPLGLELTADKKTCVEPE 607 P C +NGGC+H+C R ++ C C G L +D K C++ + Sbjct: 266 PTNAQGCKLNNGGCAHICAERTIRGHVITKCQCRAGYHLHSDNKQCIDDD 315 Score = 34.3 bits (75), Expect = 0.60 Identities = 12/18 (66%), Positives = 12/18 (66%) Query: 1097 CDGQQDCEDGRDEAECGA 1114 CDGQ DC DG DE C A Sbjct: 243 CDGQDDCNDGSDEKNCSA 260 Score = 34.3 bits (75), Expect = 0.60 Identities = 17/38 (44%), Positives = 20/38 (52%), Gaps = 3/38 (7%) Query: 263 NNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYD 300 NN GCS LCL + Y CAC G +L + TC D Sbjct: 361 NNGGCSQLCLNTQG--SYRCACDYGYRLLSDGK-TCQD 395 Score = 33.5 bits (73), Expect = 1.0 Identities = 14/33 (42%), Positives = 17/33 (51%), Gaps = 4/33 (12%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHY 897 N+C NGGC H C+ G +RC C A Y Sbjct: 438 NECETSNGGCEHRCVNDKG----GFRCECYAGY 466 Score = 33.1 bits (72), Expect = 1.4 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 6/51 (11%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE-FLL 914 ++C N C H+C+ PG Y CAC + L D +C++ +E FLL Sbjct: 315 DECSNPNR-CDHVCINNPGS----YACACHKGFFLKLDERSCADLDECFLL 360 Score = 33.1 bits (72), Expect = 1.4 Identities = 12/28 (42%), Positives = 13/28 (46%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLG 593 N C NGGC H C N + C C G Sbjct: 438 NECETSNGGCEHRCVNDKGGFRCECYAG 465 Score = 30.7 bits (66), Expect = 7.4 Identities = 13/41 (31%), Positives = 18/41 (43%), Gaps = 2/41 (4%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYD 300 C+ +N GC H C+ D G+ C C G + C D Sbjct: 440 CETSNGGCEHRCV--NDKGGFRCECYAGYMQDVMMPSRCMD 478 Score = 30.3 bits (65), Expect = 9.8 Identities = 13/33 (39%), Positives = 15/33 (45%), Gaps = 1/33 (3%) Query: 573 GGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 G C HLC N + C C G L K CV+ Sbjct: 571 GDCEHLCTNTVGSFSCSCHQGYRLKG-KHQCVD 602 >SB_18886| Best HMM Match : PPC (HMM E-Value=9.4) Length = 116 Score = 47.2 bits (107), Expect = 8e-05 Identities = 27/96 (28%), Positives = 51/96 (53%), Gaps = 6/96 (6%) Query: 123 WTDW-GEIPKIERAGMNGDPATRKVIVRDNI-FWPNGITVDYNNSLIYWV---DAKLQFV 177 W +W P+I RA ++G T V + ++ +T+DY+ +YW+ DA + + Sbjct: 13 WWNWTNNRPRIVRASLSGGNPTDIVFFPSSYKYYKIVLTLDYSQKRVYWIHGYDASVLTL 72 Query: 178 DVIDFNGEKRKRVVKGGL-VYPFALTFSNDKLYWTD 212 + D+ G R++ + G+ PF++TF D +Y+ D Sbjct: 73 ESSDYYGLDRQKHINEGINPTPFSMTFLKDTVYYGD 108 Score = 37.9 bits (84), Expect = 0.049 Identities = 28/104 (26%), Positives = 54/104 (51%), Gaps = 10/104 (9%) Query: 738 YWSELGSKS-IKRAAMDGSSVS--VFMEQVGRVH--ALAIDYERRAIYWA-ALDPPVV-- 789 +W+ ++ I RA++ G + + VF + + L +DY ++ +YW D V+ Sbjct: 13 WWNWTNNRPRIVRASLSGGNPTDIVFFPSSYKYYKIVLTLDYSQKRVYWIHGYDASVLTL 72 Query: 790 EFAFLNGTGRQT-LADNI-PMPYALALFNDSVYWGDWNTGQIQQ 831 E + G RQ + + I P P+++ D+VY+GD NT +++ Sbjct: 73 ESSDYYGLDRQKHINEGINPTPFSMTFLKDTVYYGDSNTRTVER 116 Score = 31.1 bits (67), Expect = 5.6 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 7/83 (8%) Query: 433 WMFWSDWNEKKPKIERANLDGSGR---VLLISEKLTWPNSIALDTVNNKLYW---GDART 486 ++ W +W +P+I RA+L G V S + + LD ++YW DA Sbjct: 10 YLDWWNWTNNRPRIVRASLSGGNPTDIVFFPSSYKYYKIVLTLDYSQKRVYWIHGYDASV 69 Query: 487 HKIEVCNMDGTERKELHSNDIIH 509 +E + G +R++ H N+ I+ Sbjct: 70 LTLESSDYYGLDRQK-HINEGIN 91 >SB_13199| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 259 Score = 46.4 bits (105), Expect = 1e-04 Identities = 18/38 (47%), Positives = 22/38 (57%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 CA+ NGGCS C N P +C CP+GL L CV+ Sbjct: 103 CAERNGGCSDTCRNTPRGAVCECPIGLTLGGGGHACVD 140 Score = 36.7 bits (81), Expect = 0.11 Identities = 13/27 (48%), Positives = 17/27 (62%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 F C+ LC+ ++CDG C DGSDE Sbjct: 26 FECENKLCVPRTWLCDGDNDCHDGSDE 52 Score = 35.5 bits (78), Expect = 0.26 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 23/80 (28%) Query: 1097 CDGQQDCEDGRDEAECGACG-GDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEGLC 1155 CDG DC DG DE C + V+C + F C C Sbjct: 40 CDGDNDCHDGSDEKNCESRRMRTVKCG----------------------IEEFDCGNSTC 77 Query: 1156 IAARFVCDGRPQCADGSDEA 1175 I +CDG CAD SDE+ Sbjct: 78 IPLTVLCDGLYDCADRSDES 97 Score = 32.3 bits (70), Expect = 2.4 Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEA---FLVYSRKNIIGRLSIK 624 CA+ CS C N +Y C C G + TA C + L++S K+ RL I Sbjct: 144 CAEGKDDCSQTCANTHGEYECACVDGYKQTAAGHGCQAKDMSGFALMFSAKS---RLYIT 200 Query: 625 NEYNDAVIP 633 V+P Sbjct: 201 RSLKGVVVP 209 >SB_55908| Best HMM Match : Sushi (HMM E-Value=1.6e-12) Length = 465 Score = 46.0 bits (104), Expect = 2e-04 Identities = 19/37 (51%), Positives = 21/37 (56%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKT 602 N C +NGGCSH C N Y C CP G E+ A KT Sbjct: 188 NECLVNNGGCSHGCVNLVGRYYCSCPKGFEVGASGKT 224 Score = 36.3 bits (80), Expect = 0.15 Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 4/61 (6%) Query: 239 VPADIKVYDESRQIISAEDY--PCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSST 296 VP D +V+ R + D+ C NN GCSH C+ Y C+CP G ++ + T Sbjct: 167 VPVDSEVFPCMRLEVFGCDHINECLVNNGGCSHGCVNLVG--RYYCSCPKGFEVGASGKT 224 Query: 297 T 297 T Sbjct: 225 T 225 Score = 35.9 bits (79), Expect = 0.20 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 4/47 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 N+C V+NGGCSH C+ G Y C+CP + + T + ++ Sbjct: 188 NECLVNNGGCSHGCVNLVG----RYYCSCPKGFEVGASGKTTDKCDD 230 >SB_51974| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 3474 Score = 46.0 bits (104), Expect = 2e-04 Identities = 17/31 (54%), Positives = 21/31 (67%) Query: 575 CSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 CSH C N P +IC CP GL L+ D K+CV+ Sbjct: 365 CSHQCLNTPGSFICTCPEGLALSEDGKSCVD 395 Score = 41.1 bits (92), Expect = 0.005 Identities = 13/36 (36%), Positives = 21/36 (58%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 C+ C+ +C N+P Y C C G +L AD+++C Sbjct: 874 CSTSTHNCTQICVNQPGSYTCHCHQGYQLAADQRSC 909 Score = 37.9 bits (84), Expect = 0.049 Identities = 16/38 (42%), Positives = 20/38 (52%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 CA C+ C N P Y C C LG +L DKK C++ Sbjct: 630 CAAGFHQCNQNCQNIPGSYNCTCGLGYQLAYDKKNCLD 667 Score = 37.5 bits (83), Expect = 0.064 Identities = 16/48 (33%), Positives = 22/48 (45%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYSRK 615 CA C+ C N +Y C C G EL D+ CV+ + + S K Sbjct: 671 CATGKHQCAQNCTNIIGNYSCSCTTGFELAVDQTNCVDVDECVTRSHK 718 Score = 35.1 bits (77), Expect = 0.34 Identities = 12/31 (38%), Positives = 16/31 (51%) Query: 575 CSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 C+ C N P Y+C C G L D TC++ Sbjct: 481 CNQTCSNIPGSYVCSCVTGYYLGVDNTTCLD 511 Score = 34.3 bits (75), Expect = 0.60 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 4/38 (10%) Query: 874 CSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 CSH CL TPG + C CP L++D +C + +E Sbjct: 365 CSHQCLNTPG----SFICTCPEGLALSEDGKSCVDVDE 398 Score = 33.9 bits (74), Expect = 0.79 Identities = 14/43 (32%), Positives = 21/43 (48%) Query: 563 LGWNPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 L + C+ + C C N +IC C G L +D K+CV+ Sbjct: 510 LDLDECSTNANNCEQRCTNSLGSFICSCWTGYILGSDYKSCVD 552 Score = 33.5 bits (73), Expect = 1.0 Identities = 15/42 (35%), Positives = 20/42 (47%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPE 607 N C CS C N + C C G L +DK+TC++ E Sbjct: 751 NECKSSIKYCSQGCKNLYGTFSCFCYRGYALDSDKRTCIDVE 792 Score = 33.1 bits (72), Expect = 1.4 Identities = 13/36 (36%), Positives = 17/36 (47%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 C+ GCS +C N + CGC G L D +C Sbjct: 794 CSSGAHGCSQICNNTQGSFHCGCHQGYNLLDDLISC 829 Score = 32.7 bits (71), Expect = 1.8 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 4/38 (10%) Query: 874 CSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 CSH C TPG YRC+C Y+ N +C + +E Sbjct: 840 CSHNCTNTPGS----YRCSCFPGYQQGPKNDSCLDVDE 873 Score = 31.5 bits (68), Expect = 4.2 Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 4/46 (8%) Query: 866 QCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 +C GCS +C T G + C C Y L D I+C + +E Sbjct: 793 ECSSGAHGCSQICNNTQGS----FHCGCHQGYNLLDDLISCGDIDE 834 Score = 31.1 bits (67), Expect = 5.6 Identities = 12/36 (33%), Positives = 19/36 (52%) Query: 878 CLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFL 913 C P ++ +Y C C A Y L+ D +C + +E L Sbjct: 440 CFPRCSNINGNYSCECSAGYVLSSDFTSCLDVDECL 475 Score = 30.7 bits (66), Expect = 7.4 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 3/34 (8%) Query: 267 CSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYD 300 CSH CL +P + C CP G+ L E+ +C D Sbjct: 365 CSHQCLNTPG--SFICTCPEGLALSEDGK-SCVD 395 Score = 30.3 bits (65), Expect = 9.8 Identities = 12/38 (31%), Positives = 19/38 (50%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 C+ + C+ C N P Y C C G L + ++CV+ Sbjct: 589 CSSNLHICNQTCNNVPGSYYCTCFPGFYLMMEDQSCVD 626 Score = 30.3 bits (65), Expect = 9.8 Identities = 12/44 (27%), Positives = 20/44 (45%), Gaps = 4/44 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSE 908 ++C C+ +C+ PG Y C C Y+L D +C + Sbjct: 872 DECSTSTHNCTQICVNQPG----SYTCHCHQGYQLAADQRSCEK 911 >SB_26052| Best HMM Match : EGF (HMM E-Value=4e-06) Length = 42 Score = 45.6 bits (103), Expect = 2e-04 Identities = 20/42 (47%), Positives = 25/42 (59%), Gaps = 4/42 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 N+C V NGGCSH C+ T G Y C CP + +L+KD C Sbjct: 3 NECNVLNGGCSHTCVNTIG----GYYCKCPPYLKLDKDMHRC 40 Score = 41.5 bits (93), Expect = 0.004 Identities = 18/38 (47%), Positives = 19/38 (50%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N C NGGCSH C N Y C CP L+L D C Sbjct: 3 NECNVLNGGCSHTCVNTIGGYYCKCPPYLKLDKDMHRC 40 Score = 31.5 bits (68), Expect = 4.2 Identities = 14/31 (45%), Positives = 17/31 (54%), Gaps = 2/31 (6%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKL 290 C N GCSH C+ + GY C CP +KL Sbjct: 5 CNVLNGGCSHTCVNTIG--GYYCKCPPYLKL 33 >SB_39808| Best HMM Match : EGF_CA (HMM E-Value=6.3e-35) Length = 850 Score = 44.8 bits (101), Expect = 4e-04 Identities = 17/38 (44%), Positives = 21/38 (55%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 C DD C C N P Y CGC G L++D KTC++ Sbjct: 290 CLDDAHLCDQRCTNTPGSYACGCYHGYSLSSDMKTCID 327 Score = 38.3 bits (85), Expect = 0.037 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFLLFAQKNAVGRI 924 ++C + + GCS LC T G Y C C + Y L DN TC+E + AQ V Sbjct: 329 DECTMTSHGCSQLCNNTLGG----YNCYCLSGYSLGNDNRTCTELRSY-RGAQSITVSAG 383 Query: 925 MVANG 929 M A G Sbjct: 384 MAALG 388 Score = 37.5 bits (83), Expect = 0.064 Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFL 913 N+C + C +C+ T G +RC C Y L D+ TCS+ +E L Sbjct: 247 NECEIRKHTCDQVCVNTIGS----FRCGCNVGYTLRNDSKTCSDIDECL 291 Score = 36.3 bits (80), Expect = 0.15 Identities = 16/42 (38%), Positives = 20/42 (47%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAF 609 C + GCS LC N Y C C G L D +TC E ++ Sbjct: 331 CTMTSHGCSQLCNNTLGGYNCYCLSGYSLGNDNRTCTELRSY 372 Score = 34.7 bits (76), Expect = 0.45 Identities = 14/38 (36%), Positives = 17/38 (44%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N C C +C N + CGC +G L D KTC Sbjct: 247 NECEIRKHTCDQVCVNTIGSFRCGCNVGYTLRNDSKTC 284 Score = 31.1 bits (67), Expect = 5.6 Identities = 16/39 (41%), Positives = 20/39 (51%), Gaps = 3/39 (7%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTC 298 C + GCS LC + GYNC C +G L N + TC Sbjct: 331 CTMTSHGCSQLC--NNTLGGYNCYCLSGYSL-GNDNRTC 366 >SB_58882| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 1027 Score = 44.4 bits (100), Expect = 6e-04 Identities = 19/39 (48%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 566 NPCADDNGGCSHLCFNRPD-DYICGCPLGLELTADKKTC 603 N C NGGC H C N P+ Y C C G L AD+K C Sbjct: 779 NECVVGNGGCQHGCVNNPEGSYHCICNYGFVLDADRKKC 817 Score = 35.9 bits (79), Expect = 0.20 Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 3/42 (7%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 N+C V NGGC H C+ P Y C C + L+ D C Sbjct: 779 NECVVGNGGCQHGCVNNP---EGSYHCICNYGFVLDADRKKC 817 >SB_13477| Best HMM Match : Ldl_recept_a (HMM E-Value=0) Length = 628 Score = 44.0 bits (99), Expect = 7e-04 Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 21/90 (23%) Query: 1094 SRQCDGQQDCEDGRDEAECGACGGDVRC-ADGTXXXXXXXXXXXXXXXXXXXXDAFRCDE 1152 S++CDGQ DC D DE C C AD F Sbjct: 165 SQRCDGQNDCGDWSDETGCSTPPIPTTCPADWVR--------------------CFYNSS 204 Query: 1153 GLCIAARFVCDGRPQCADGSDEAPAACAYG 1182 GLCI+ ++C+GR C D DE PA C G Sbjct: 205 GLCISTSWLCNGRVDCPDAWDEQPAQCRSG 234 Score = 39.9 bits (89), Expect = 0.012 Identities = 26/87 (29%), Positives = 31/87 (35%), Gaps = 7/87 (8%) Query: 1095 RQCD-GQQDCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXX------XXXXXDA 1147 R C+ GQ C +GR + C D C DG+ Sbjct: 48 RSCNSGQFSCSNGRCISRSWVCDRDNDCGDGSDERNCSYPTTGPWTTRPWTPISSCRSWE 107 Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 F C G C+ R VCDG C D SDE Sbjct: 108 FSCLNGRCVFYRLVCDGVDDCGDSSDE 134 Score = 37.9 bits (84), Expect = 0.049 Identities = 15/30 (50%), Positives = 18/30 (60%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPA 1177 FRC+ G CI + CDG C D SDE P+ Sbjct: 15 FRCNNGRCIPMSWRCDGDNDCGDMSDEPPS 44 Score = 37.1 bits (82), Expect = 0.085 Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 2/37 (5%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAACAYGHT 1184 F C G CI+ +VCD C DGSDE C+Y T Sbjct: 55 FSCSNGRCISRSWVCDRDNDCGDGSDE--RNCSYPTT 89 >SB_11375| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 651 Score = 43.6 bits (98), Expect = 0.001 Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 4/47 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 ++C +NGGCS CL T G CAC A Y L D +TC + +E Sbjct: 24 DECKTNNGGCSQRCLNTNG----SRACACDAGYDLEADGVTCVDIDE 66 Score = 43.2 bits (97), Expect = 0.001 Identities = 17/38 (44%), Positives = 20/38 (52%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 C +NGGCS C N C C G +L AD TCV+ Sbjct: 26 CKTNNGGCSQRCLNTNGSRACACDAGYDLEADGVTCVD 63 Score = 38.3 bits (85), Expect = 0.037 Identities = 16/40 (40%), Positives = 18/40 (45%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 N C NG CSH C N + C C G LT CV+ Sbjct: 105 NECVTSNGNCSHTCVNWEGGFNCTCAEGYALTYGGYECVD 144 Score = 38.3 bits (85), Expect = 0.037 Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 1/40 (2%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPE 607 C D N C C N P Y C C G EL D KTC + + Sbjct: 231 CLDSNT-CQQTCTNLPGSYRCSCYKGYELDLDGKTCSDKD 269 Score = 36.7 bits (81), Expect = 0.11 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 5/48 (10%) Query: 864 SNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 +++C +D+ C C PG YRC+C Y L+ D TCS+ +E Sbjct: 228 TDEC-LDSNTCQQTCTNLPGS----YRCSCYKGYELDLDGKTCSDKDE 270 Score = 34.3 bits (75), Expect = 0.60 Identities = 14/32 (43%), Positives = 15/32 (46%) Query: 574 GCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 GC C N P Y C C G L D K+C E Sbjct: 316 GCQDSCLNSPGSYKCACSDGKLLAMDGKSCKE 347 Score = 33.9 bits (74), Expect = 0.79 Identities = 18/41 (43%), Positives = 19/41 (46%), Gaps = 3/41 (7%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYD 300 CK NN GCS CL + CAC G L E TC D Sbjct: 26 CKTNNGGCSQRCLNTNGSRA--CACDAGYDL-EADGVTCVD 63 Score = 33.9 bits (74), Expect = 0.79 Identities = 15/47 (31%), Positives = 20/47 (42%), Gaps = 4/47 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 N+C NG CSH C+ G + C C Y L C + +E Sbjct: 105 NECVTSNGNCSHTCVNWEG----GFNCTCAEGYALTYGGYECVDIDE 147 Score = 33.1 bits (72), Expect = 1.4 Identities = 11/29 (37%), Positives = 14/29 (48%) Query: 575 CSHLCFNRPDDYICGCPLGLELTADKKTC 603 C H C N ++C C G L +D TC Sbjct: 153 CDHTCRNTNGSFVCSCREGFRLLSDNTTC 181 Score = 32.7 bits (71), Expect = 1.8 Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 575 CSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 CS LC N Y C C G L+A++ CV+ Sbjct: 277 CSQLCTNTAGGYQCSCHHGYVLSANQHACVD 307 Score = 31.9 bits (69), Expect = 3.2 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 3/45 (6%) Query: 261 KKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQML 305 KK + C CL P GYNC C +G L + + TC D+ + L Sbjct: 191 KKTSLSCGQRCLNFPG--GYNCTCNSGFILIPD-NRTCNDTDECL 232 Score = 31.5 bits (68), Expect = 4.2 Identities = 13/36 (36%), Positives = 16/36 (44%) Query: 575 CSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFL 610 C C N P Y C C G L D +TC + + L Sbjct: 197 CGQRCLNFPGGYNCTCNSGFILIPDNRTCNDTDECL 232 Score = 31.1 bits (67), Expect = 5.6 Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 4/40 (10%) Query: 874 CSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFL 913 C CL PG Y C C + + L DN TC++ +E L Sbjct: 197 CGQRCLNFPGG----YNCTCNSGFILIPDNRTCNDTDECL 232 Score = 30.7 bits (66), Expect = 7.4 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 4/38 (10%) Query: 874 CSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 C H C T G + C+C +RL DN TC + +E Sbjct: 153 CDHTCRNTNGS----FVCSCREGFRLLSDNTTCRDIDE 186 Score = 30.3 bits (65), Expect = 9.8 Identities = 11/31 (35%), Positives = 14/31 (45%) Query: 575 CSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 C + C N + C C G L AD TC + Sbjct: 73 CQYSCTNTNGSFYCSCRHGYALQADNTTCAD 103 >SB_35576| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1315 Score = 43.6 bits (98), Expect = 0.001 Identities = 29/94 (30%), Positives = 34/94 (36%), Gaps = 14/94 (14%) Query: 1097 CDGQQDCEDGRDEAEC-----------GACGGDVRCADGTXXXXXXXXXXXXXXXXXXXX 1145 CDG C D DEA C G C V DGT Sbjct: 1138 CDGDNACLDFSDEANCKCLSSKFACESGECIDVVGLCDGTDDCKDASDESRCDHKCSK-- 1195 Query: 1146 DAFRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 D ++C G C+ CDG+ C DG+DE P C Sbjct: 1196 DEYQCVSGACVKWPLTCDGKKDCEDGTDE-PGIC 1228 Score = 37.1 bits (82), Expect = 0.085 Identities = 14/32 (43%), Positives = 18/32 (56%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 F+C G C++ +CDG C D SDEA C Sbjct: 1124 FQCVNGQCVSRDLICDGDNACLDFSDEANCKC 1155 >SB_15410| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1147 Score = 43.6 bits (98), Expect = 0.001 Identities = 17/38 (44%), Positives = 20/38 (52%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N C DNG CS +C N Y+C C G L D +TC Sbjct: 257 NECLVDNGRCSEMCNNTLGSYLCDCGAGFALQPDGRTC 294 Score = 40.7 bits (91), Expect = 0.007 Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 4/47 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 N+C VDNG CS +C T G Y C C A + L D TC + +E Sbjct: 257 NECLVDNGRCSEMCNNTLG----SYLCDCGAGFALQPDGRTCRDIDE 299 Score = 35.1 bits (77), Expect = 0.34 Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 2/47 (4%) Query: 566 NPCADDNGGCSH-LCFNRPDDYICGCPLGLELTADKKTCVEPEAFLV 611 N C+D G C H C N Y C C G E TAD K CV+ LV Sbjct: 216 NECSDP-GVCVHGRCENFNGGYQCICNRGFESTADMKDCVDINECLV 261 Score = 33.5 bits (73), Expect = 1.0 Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 6/38 (15%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 NPCAD C+N Y C CP G+EL D +C Sbjct: 181 NPCADGT------CYNTMGSYKCVCPDGMELMKDGVSC 212 Score = 30.7 bits (66), Expect = 7.4 Identities = 13/39 (33%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 566 NPCADDNGGCSH-LCFNRPDDYICGCPLGLELTADKKTC 603 N C D C H C N+ ++C C +G T + K C Sbjct: 540 NECLADPNLCEHGQCINKAGSFMCDCEIGYLPTPNGKGC 578 Score = 30.3 bits (65), Expect = 9.8 Identities = 11/28 (39%), Positives = 15/28 (53%) Query: 578 LCFNRPDDYICGCPLGLELTADKKTCVE 605 +C N P Y C C GL L + + CV+ Sbjct: 10 ICVNTPGSYRCECSAGLTLDSIQNACVD 37 >SB_57009| Best HMM Match : Zona_pellucida (HMM E-Value=0) Length = 564 Score = 43.2 bits (97), Expect = 0.001 Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 4/42 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 N+C GGCSH C+ T G Y C CP L+KDN TC Sbjct: 113 NECRFRKGGCSHKCVNTIG----GYHCECPDPLVLDKDNRTC 150 Score = 41.9 bits (94), Expect = 0.003 Identities = 18/38 (47%), Positives = 19/38 (50%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N C GGCSH C N Y C CP L L D +TC Sbjct: 113 NECRFRKGGCSHKCVNTIGGYHCECPDPLVLDKDNRTC 150 Score = 32.3 bits (70), Expect = 2.4 Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 2/47 (4%) Query: 250 RQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSST 296 R I + C+ GCSH C+ + GY+C CP + L +++ T Sbjct: 105 RSISCVDRNECRFRKGGCSHKCVNTIG--GYHCECPDPLVLDKDNRT 149 >SB_6273| Best HMM Match : MAM (HMM E-Value=0) Length = 4272 Score = 42.7 bits (96), Expect = 0.002 Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 1/44 (2%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAAC-AYGHTDQVNGI 1190 FRCD G CI++ CD C DGS+E + C AY + NG+ Sbjct: 2788 FRCDSGHCISSSSKCDFETDCCDGSEERNSTCTAYTRCNFENGL 2831 Score = 39.5 bits (88), Expect = 0.016 Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 3/45 (6%) Query: 1149 RCDEGLCIAARFVCDGRPQCADGSDEA--PAACAYGHTDQVNGIH 1191 RC G CI A VCD + C+DGSDEA + C + DQ N ++ Sbjct: 2556 RCSNGQCINAIQVCDFKKDCSDGSDEATCQSTCNF-EKDQCNWVN 2599 Score = 37.9 bits (84), Expect = 0.049 Identities = 14/22 (63%), Positives = 15/22 (68%) Query: 1094 SRQCDGQQDCEDGRDEAECGAC 1115 S +CD Q DC DG DEA CG C Sbjct: 2262 SLRCDYQNDCSDGLDEASCGTC 2283 Score = 37.1 bits (82), Expect = 0.085 Identities = 16/39 (41%), Positives = 19/39 (48%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAACAYGHTDQ 1186 FRC +G CI CD + C+DG DEA DQ Sbjct: 2251 FRCTDGSCIMQSLRCDYQNDCSDGLDEASCGTCNFEADQ 2289 Score = 35.1 bits (77), Expect = 0.34 Identities = 15/43 (34%), Positives = 20/43 (46%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAACAYGHTDQVNGI 1190 FRC G C ++ VCD C D SDE + D +G+ Sbjct: 3625 FRCTRGSCTSSDNVCDFSDDCGDSSDERSCSSYNNRCDFTSGL 3667 Score = 34.3 bits (75), Expect = 0.60 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 4/47 (8%) Query: 1148 FRC-DEGLCIAARFVCDGRPQCADGSDE--APAACAYGHTDQVNGIH 1191 F C +G CI VCD C DGSDE P+ C + T Q +H Sbjct: 3430 FGCVTDGKCIPLTSVCDFNVDCLDGSDERSCPSNCTF-ETGQCGWVH 3475 Score = 33.1 bits (72), Expect = 1.4 Identities = 14/27 (51%), Positives = 14/27 (51%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 FRC G CI VCD C D SDE Sbjct: 2098 FRCARGSCIDTGRVCDFTDDCGDNSDE 2124 >SB_26480| Best HMM Match : EGF (HMM E-Value=0) Length = 1772 Score = 42.3 bits (95), Expect = 0.002 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 4/39 (10%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDN 903 N+C V N C+ LC+ TPG Y CAC YRL+ +N Sbjct: 1735 NECSVGNHRCAQLCINTPG----SYNCACAKGYRLDNNN 1769 Score = 36.3 bits (80), Expect = 0.15 Identities = 15/39 (38%), Positives = 18/39 (46%), Gaps = 2/39 (5%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCV 604 N C+ N C+ LC N P Y C C G L D C+ Sbjct: 1735 NECSVGNHRCAQLCINTPGSYNCACAKGYRL--DNNNCI 1771 Score = 33.9 bits (74), Expect = 0.79 Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 2/35 (5%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENS 294 C N C+ LC+ +P YNCAC G +L N+ Sbjct: 1737 CSVGNHRCAQLCINTPG--SYNCACAKGYRLDNNN 1769 >SB_47055| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 933 Score = 41.5 bits (93), Expect = 0.004 Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%) Query: 542 QPVVEQMANMMGVKAFRLGAPLGWNPCADDNGGCSHLCFNRPDDYI-CGCPLGLELTADK 600 Q + + + + V + APL + C DNGGC +C+N + + CGC G ++ D Sbjct: 427 QMIGKGILTLCEVSVYSRTAPLA-DLCQLDNGGCEQVCYNLCNLKVKCGCYPGFKMAYDG 485 Query: 601 KTCVE 605 +TC++ Sbjct: 486 RTCID 490 Score = 39.5 bits (88), Expect = 0.016 Identities = 16/38 (42%), Positives = 18/38 (47%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N C NGGC H C + Y C C G L D K+C Sbjct: 578 NECLVKNGGCEHTCKDYEGGYYCTCNPGYRLMDDDKSC 615 Score = 39.1 bits (87), Expect = 0.021 Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 4/42 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 N+C V NGGC H C D Y C C YRL D+ +C Sbjct: 578 NECLVKNGGCEHTC----KDYEGGYYCTCNPGYRLMDDDKSC 615 Score = 37.1 bits (82), Expect = 0.085 Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 1/42 (2%) Query: 260 CKKNNAGCSHLCLLSPDPPG-YNCACPTGVKLRENSSTTCYD 300 C+ NN GC + PG ++CAC G +L+ENS C D Sbjct: 494 CQVNNGGCDIFHGQCINTPGSHHCACRNGYQLKENSKYVCED 535 Score = 37.1 bits (82), Expect = 0.085 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 4/50 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFLL 914 N+C V N GC H+C T G + C C Y+L C E L+ Sbjct: 537 NECNVANAGCEHICENTHG----SFNCDCRQGYKLKAGGYGCENINECLV 582 Score = 33.9 bits (74), Expect = 0.79 Identities = 14/38 (36%), Positives = 17/38 (44%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N C N GC H+C N + C C G +L A C Sbjct: 537 NECNVANAGCEHICENTHGSFNCDCRQGYKLKAGGYGC 574 Score = 33.5 bits (73), Expect = 1.0 Identities = 17/69 (24%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Query: 843 IRKDLDYISDLKLYHRAKSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKD 902 I K + + ++ +Y R + ++ C +DNGGC +C +C C +++ D Sbjct: 429 IGKGILTLCEVSVYSRTAPL-ADLCQLDNGGCEQVCYNL---CNLKVKCGCYPGFKMAYD 484 Query: 903 NITCSEPEE 911 TC + +E Sbjct: 485 GRTCIDIDE 493 Score = 31.5 bits (68), Expect = 4.2 Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 8/51 (15%) Query: 865 NQCGVDNGGCS--H-LCLPTPGDVRTDYRCACPAHYRLNKDN-ITCSEPEE 911 ++C V+NGGC H C+ TPG + CAC Y+L +++ C + E Sbjct: 492 DECQVNNGGCDIFHGQCINTPG----SHHCACRNGYQLKENSKYVCEDLNE 538 Score = 31.5 bits (68), Expect = 4.2 Identities = 14/44 (31%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Query: 248 ESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLR 291 E+ + + + C NAGC H+C +NC C G KL+ Sbjct: 527 ENSKYVCEDLNECNVANAGCEHIC--ENTHGSFNCDCRQGYKLK 568 >SB_20531| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 796 Score = 41.5 bits (93), Expect = 0.004 Identities = 16/34 (47%), Positives = 19/34 (55%) Query: 1146 DAFRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 + F C G C+ VCDG C+D SDEAP C Sbjct: 219 EEFPCASGDCVPLTSVCDGSADCSDSSDEAPELC 252 >SB_48688| Best HMM Match : Ldl_recept_a (HMM E-Value=7.8e-26) Length = 351 Score = 41.5 bits (93), Expect = 0.004 Identities = 24/92 (26%), Positives = 30/92 (32%), Gaps = 9/92 (9%) Query: 1096 QCDGQQDCEDGRDEAECGACGGDVRCADG--------TXXXXXXXXXXXXXXXXXXXXDA 1147 +CDG C D DE C + +C DG Sbjct: 56 RCDGDYACVDHSDERNCACRSAEFKCPDGKCVHPSKFCNGESDCTDGSDEWSCDNSCSSR 115 Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 C +G C+ C+G C DGSDE P C Sbjct: 116 HACADGTCVTWSLTCNGVSDCQDGSDE-PKLC 146 Score = 38.7 bits (86), Expect = 0.028 Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 2/49 (4%) Query: 1146 DAFRCDEGLCIAARFVCDGRPQCADGSDEAPAACAYGHTDQVNG--IHP 1192 D F+C G+C+ CDG C D SDE AC +G +HP Sbjct: 41 DQFQCLNGMCVGQEVRCDGDYACVDHSDERNCACRSAEFKCPDGKCVHP 89 Score = 38.7 bits (86), Expect = 0.028 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 1/33 (3%) Query: 1094 SRQCDGQQDCEDGRDEAEC-GACGGDVRCADGT 1125 S+ C+G+ DC DG DE C +C CADGT Sbjct: 90 SKFCNGESDCTDGSDEWSCDNSCSSRHACADGT 122 Score = 36.7 bits (81), Expect = 0.11 Identities = 23/82 (28%), Positives = 30/82 (36%), Gaps = 12/82 (14%) Query: 1094 SRQCDGQQ-DCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDE 1152 S C G Q C +G + C GD C D + F+C + Sbjct: 35 SHSCHGDQFQCLNGMCVGQEVRCDGDYACVDHSDERNCACRSAE-----------FKCPD 83 Query: 1153 GLCIAARFVCDGRPQCADGSDE 1174 G C+ C+G C DGSDE Sbjct: 84 GKCVHPSKFCNGESDCTDGSDE 105 >SB_30577| Best HMM Match : Ldl_recept_a (HMM E-Value=2.8e-25) Length = 147 Score = 41.5 bits (93), Expect = 0.004 Identities = 24/92 (26%), Positives = 30/92 (32%), Gaps = 9/92 (9%) Query: 1096 QCDGQQDCEDGRDEAECGACGGDVRCADG--------TXXXXXXXXXXXXXXXXXXXXDA 1147 +CDG C D DE C + +C DG Sbjct: 56 RCDGDYACVDHSDERNCACRSAEFKCPDGKCVHPSKFCNGESDCTDGSDEWSCDNSCSSR 115 Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 C +G C+ C+G C DGSDE P C Sbjct: 116 HACADGTCVTWSLTCNGVSDCQDGSDE-PKLC 146 Score = 39.1 bits (87), Expect = 0.021 Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 2/49 (4%) Query: 1146 DAFRCDEGLCIAARFVCDGRPQCADGSDEAPAACAYGHTDQVNG--IHP 1192 D F+C G+C+ CDG C D SDE AC +G +HP Sbjct: 41 DQFQCLNGMCVGQELRCDGDYACVDHSDERNCACRSAEFKCPDGKCVHP 89 Score = 38.7 bits (86), Expect = 0.028 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 1/33 (3%) Query: 1094 SRQCDGQQDCEDGRDEAEC-GACGGDVRCADGT 1125 S+ C+G+ DC DG DE C +C CADGT Sbjct: 90 SKFCNGESDCTDGSDEWSCDNSCSSRHACADGT 122 Score = 36.3 bits (80), Expect = 0.15 Identities = 23/82 (28%), Positives = 30/82 (36%), Gaps = 12/82 (14%) Query: 1094 SRQCDGQQ-DCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDE 1152 S C G Q C +G + C GD C D + F+C + Sbjct: 35 SHSCHGDQFQCLNGMCVGQELRCDGDYACVDHSDERNCACRSAE-----------FKCPD 83 Query: 1153 GLCIAARFVCDGRPQCADGSDE 1174 G C+ C+G C DGSDE Sbjct: 84 GKCVHPSKFCNGESDCTDGSDE 105 >SB_50311| Best HMM Match : Ldl_recept_a (HMM E-Value=3.4e-20) Length = 772 Score = 41.1 bits (92), Expect = 0.005 Identities = 16/32 (50%), Positives = 17/32 (53%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 F+CD G CI CDG C DGSDE C Sbjct: 96 FQCDNGKCIRKNLYCDGDFACVDGSDETRCEC 127 Score = 37.5 bits (83), Expect = 0.064 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 11/80 (13%) Query: 1099 GQQDCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEGLCIAA 1158 G+ C++G+ + C GD C DG+ + F C G CI Sbjct: 94 GEFQCDNGKCIRKNLYCDGDFACVDGSDETRCECPS-----------NMFLCPSGECIMG 142 Query: 1159 RFVCDGRPQCADGSDEAPAA 1178 +CDG+ C D +DE A Sbjct: 143 TQLCDGKKDCTDNTDEKNCA 162 >SB_5000| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 1050 Score = 41.1 bits (92), Expect = 0.005 Identities = 18/43 (41%), Positives = 23/43 (53%) Query: 561 APLGWNPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 A L + C+ CS C N Y CGCP G +L +D+KTC Sbjct: 736 ATLDIDECSRKTHKCSDSCLNTVGFYNCGCPPGYKLMSDEKTC 778 Score = 40.3 bits (90), Expect = 0.009 Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 5/44 (11%) Query: 865 NQCGVD-NGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCS 907 N+C C +C+ +VR+ Y+CACP + LN DN TCS Sbjct: 620 NECATPVTNDCEMICV----NVRSSYKCACPTGFILNSDNKTCS 659 Score = 37.5 bits (83), Expect = 0.064 Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 566 NPCADD-NGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N CA C +C N Y C CP G L +D KTC Sbjct: 620 NECATPVTNDCEMICVNVRSSYKCACPTGFILNSDNKTC 658 Score = 35.5 bits (78), Expect = 0.26 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 4/47 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 ++C CS CL T G Y C CP Y+L D TC + +E Sbjct: 741 DECSRKTHKCSDSCLNTVGF----YNCGCPPGYKLMSDEKTCQDVDE 783 Score = 31.5 bits (68), Expect = 4.2 Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 3/41 (7%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYD 300 C + CS CL + YNC CP G KL + TC D Sbjct: 743 CSRKTHKCSDSCLNTVG--FYNCGCPPGYKLMSDEK-TCQD 780 >SB_55657| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 868 Score = 41.1 bits (92), Expect = 0.005 Identities = 18/43 (41%), Positives = 23/43 (53%) Query: 561 APLGWNPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 A L + C+ CS C N Y CGCP G +L +D+KTC Sbjct: 511 ATLDIDECSRKTHKCSDSCLNTVGFYNCGCPPGYKLMSDEKTC 553 Score = 40.7 bits (91), Expect = 0.007 Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 566 NPCADD-NGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N CA C +C N Y C CP G L +DKKTC Sbjct: 395 NECATPVTNDCEMICINARSSYKCACPTGFILNSDKKTC 433 Score = 36.7 bits (81), Expect = 0.11 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 5/44 (11%) Query: 865 NQCGVD-NGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCS 907 N+C C +C+ + R+ Y+CACP + LN D TCS Sbjct: 395 NECATPVTNDCEMICI----NARSSYKCACPTGFILNSDKKTCS 434 Score = 35.5 bits (78), Expect = 0.26 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 4/47 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 ++C CS CL T G Y C CP Y+L D TC + +E Sbjct: 516 DECSRKTHKCSDSCLNTVGF----YNCGCPPGYKLMSDEKTCQDVDE 558 Score = 34.7 bits (76), Expect = 0.45 Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 1/40 (2%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 N C N CS +C N Y C C G L+ D KTC + Sbjct: 355 NECNYPND-CSQMCSNTAGSYKCSCVNGFVLSNDLKTCAD 393 Score = 31.5 bits (68), Expect = 4.2 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 5/47 (10%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 N+C N CS +C T G Y+C+C + L+ D TC++ E Sbjct: 355 NECNYPND-CSQMCSNTAGS----YKCSCVNGFVLSNDLKTCADINE 396 Score = 31.5 bits (68), Expect = 4.2 Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 3/41 (7%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYD 300 C + CS CL + YNC CP G KL + TC D Sbjct: 518 CSRKTHKCSDSCLNTVG--FYNCGCPPGYKLMSDEK-TCQD 555 >SB_27746| Best HMM Match : MAM (HMM E-Value=1.4013e-45) Length = 622 Score = 41.1 bits (92), Expect = 0.005 Identities = 15/34 (44%), Positives = 19/34 (55%) Query: 1146 DAFRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 D F C+ G C+ +CDG C DGSDE +C Sbjct: 186 DEFGCENGQCVKRGLLCDGDKACLDGSDEKHCSC 219 >SB_51525| Best HMM Match : EGF_CA (HMM E-Value=0.001) Length = 89 Score = 40.7 bits (91), Expect = 0.007 Identities = 16/36 (44%), Positives = 18/36 (50%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 CA NGGC H C N + C C G L DK +C Sbjct: 5 CATRNGGCDHHCHNYLGGHYCSCRAGYRLQQDKVSC 40 Score = 38.3 bits (85), Expect = 0.037 Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 4/43 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCS 907 ++C NGGC H C G + C+C A YRL +D ++C+ Sbjct: 3 DECATRNGGCDHHCHNYLGG----HYCSCRAGYRLQQDKVSCN 41 >SB_43556| Best HMM Match : Ldl_recept_a (HMM E-Value=2.7e-11) Length = 65 Score = 40.7 bits (91), Expect = 0.007 Identities = 15/28 (53%), Positives = 19/28 (67%) Query: 1147 AFRCDEGLCIAARFVCDGRPQCADGSDE 1174 +F+CD G CI+A +VCD C D SDE Sbjct: 11 SFKCDNGRCISATWVCDTENDCGDNSDE 38 >SB_41418| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 3312 Score = 40.7 bits (91), Expect = 0.007 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 4/52 (7%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFLLFA 916 N+C +NG C H C+ G YRC C Y+L + TC + +E LF+ Sbjct: 437 NECKRNNGWCEHECINIIGT----YRCRCRDGYKLEPNRRTCQDLDECALFS 484 Score = 39.1 bits (87), Expect = 0.021 Identities = 16/48 (33%), Positives = 25/48 (52%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYS 613 N C +NG C H C N Y C C G +L +++TC + + ++S Sbjct: 437 NECKRNNGWCEHECINIIGTYRCRCRDGYKLEPNRRTCQDLDECALFS 484 Score = 35.9 bits (79), Expect = 0.20 Identities = 17/42 (40%), Positives = 20/42 (47%) Query: 575 CSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYSRKN 616 C H C N Y C C G L DKK+C + LV S+ N Sbjct: 590 CEHQCNNTFGSYSCSCSPGFALADDKKSCKACKDNLVMSKIN 631 Score = 35.1 bits (77), Expect = 0.34 Identities = 13/30 (43%), Positives = 16/30 (53%) Query: 574 GCSHLCFNRPDDYICGCPLGLELTADKKTC 603 GC LC N Y C C G +L++D TC Sbjct: 485 GCEMLCHNTRGSYYCACSEGFKLSSDNFTC 514 Score = 34.7 bits (76), Expect = 0.45 Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 3/62 (4%) Query: 245 VYDESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQM 304 ++DE + CK+NN C H C+ Y C C G KL N TC D + Sbjct: 424 LHDEENGHRCVDINECKRNNGWCEHECINIIGT--YRCRCRDGYKLEPN-RRTCQDLDEC 480 Query: 305 LL 306 L Sbjct: 481 AL 482 Score = 33.5 bits (73), Expect = 1.0 Identities = 15/35 (42%), Positives = 19/35 (54%), Gaps = 4/35 (11%) Query: 873 GCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCS 907 GC LC T G Y CAC ++L+ DN TC+ Sbjct: 485 GCEMLCHNTRGS----YYCACSEGFKLSSDNFTCT 515 Score = 30.7 bits (66), Expect = 7.4 Identities = 11/27 (40%), Positives = 14/27 (51%) Query: 575 CSHLCFNRPDDYICGCPLGLELTADKK 601 C C NRP Y C CP G + D++ Sbjct: 402 CPGRCINRPGSYTCDCPRGYFVLHDEE 428 >SB_38403| Best HMM Match : PP2C (HMM E-Value=8.5e-35) Length = 916 Score = 40.3 bits (90), Expect = 0.009 Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 566 NPCAD-DNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N C D GC LC N P Y C C G + +D +TC Sbjct: 876 NECLDFSTTGCQQLCINDPGTYHCACHSGYTINSDNRTC 914 Score = 39.9 bits (89), Expect = 0.012 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 5/55 (9%) Query: 854 KLYHRAKSMGSNQC-GVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCS 907 +L + + N+C GC LC+ PG Y CAC + Y +N DN TC+ Sbjct: 865 QLAGKTRCQDINECLDFSTTGCQQLCINDPGT----YHCACHSGYTINSDNRTCT 915 Score = 38.3 bits (85), Expect = 0.037 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 1/48 (2%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYS 613 N C +NGGC HLC + + C C G +L A K C + L +S Sbjct: 836 NECNSNNGGCDHLCNDTVGSFNCSCYQGYQL-AGKTRCQDINECLDFS 882 Score = 37.5 bits (83), Expect = 0.064 Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 5/52 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFLLFA 916 N+C +NGGC HLC T G + C+C Y+L C + E L F+ Sbjct: 836 NECNSNNGGCDHLCNDTVG----SFNCSCYQGYQL-AGKTRCQDINECLDFS 882 Score = 35.5 bits (78), Expect = 0.26 Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 4/46 (8%) Query: 260 CKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTCYDSPQML 305 C NN GC HLC + +NC+C G +L T C D + L Sbjct: 838 CNSNNGGCDHLC--NDTVGSFNCSCYQGYQLA--GKTRCQDINECL 879 Score = 30.7 bits (66), Expect = 7.4 Identities = 12/34 (35%), Positives = 19/34 (55%), Gaps = 2/34 (5%) Query: 263 NNAGCSHLCLLSPDPPGYNCACPTGVKLRENSST 296 + GC LC+ DP Y+CAC +G + ++ T Sbjct: 882 STTGCQQLCI--NDPGTYHCACHSGYTINSDNRT 913 >SB_18178| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 489 Score = 39.9 bits (89), Expect = 0.012 Identities = 13/28 (46%), Positives = 20/28 (71%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEA 1175 F+C G+CI +++CDG+ C D SDE+ Sbjct: 364 FKCRSGVCIPPQWICDGKDDCGDRSDES 391 Score = 34.3 bits (75), Expect = 0.60 Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 1155 CIAARFVCDGRPQCADGSDEAPAACAYGHTDQVNGIH 1191 CI + CDG+P+CAD SDE + D+ N IH Sbjct: 285 CIDISYKCDGKPECADHSDENDCPPLI-NPDRCNVIH 320 >SB_8425| Best HMM Match : EGF (HMM E-Value=0) Length = 1955 Score = 39.9 bits (89), Expect = 0.012 Identities = 14/35 (40%), Positives = 21/35 (60%) Query: 573 GGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPE 607 G CSH C+N + C CP G+EL A ++C + + Sbjct: 1249 GICSHKCYNTKGSFRCECPAGMELAAGGRSCQDKD 1283 Score = 37.1 bits (82), Expect = 0.085 Identities = 16/38 (42%), Positives = 19/38 (50%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 CA NGGC H C N C C G L +D ++C E Sbjct: 1285 CAIQNGGCEHACANGYLRSTCQCRGGYNLESDIRSCAE 1322 Score = 35.9 bits (79), Expect = 0.20 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSE 908 ++C + NGGC H C G +R+ C C Y L D +C+E Sbjct: 1283 DECAIQNGGCEHAC--ANGYLRS--TCQCRGGYNLESDIRSCAE 1322 Score = 34.3 bits (75), Expect = 0.60 Identities = 14/47 (29%), Positives = 22/47 (46%), Gaps = 4/47 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 N+C + C+ C T G + C+C Y L D +TC++ E Sbjct: 1202 NECNSASSPCAQQCTNTEGS----FTCSCNPGYNLGSDGVTCNDVNE 1244 Score = 34.3 bits (75), Expect = 0.60 Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 5/47 (10%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 N+C + G CSH C T G +RC CPA L +C + +E Sbjct: 1243 NECSL-TGICSHKCYNTKGS----FRCECPAGMELAAGGRSCQDKDE 1284 Score = 30.7 bits (66), Expect = 7.4 Identities = 12/38 (31%), Positives = 16/38 (42%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N C + C+ C N + C C G L +D TC Sbjct: 1202 NECNSASSPCAQQCTNTEGSFTCSCNPGYNLGSDGVTC 1239 >SB_23022| Best HMM Match : CUB (HMM E-Value=0) Length = 1307 Score = 39.5 bits (88), Expect = 0.016 Identities = 15/38 (39%), Positives = 19/38 (50%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 C + GGC H+C N Y C C G L D+ +C E Sbjct: 134 CRERKGGCQHICVNTIGSYRCTCKPGFVLHPDQHSCKE 171 Score = 38.3 bits (85), Expect = 0.037 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 4/47 (8%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 ++C GGC H+C+ T G YRC C + L+ D +C E + Sbjct: 132 DECRERKGGCQHICVNTIG----SYRCTCKPGFVLHPDQHSCKEASD 174 >SB_34822| Best HMM Match : EGF_CA (HMM E-Value=8.9e-09) Length = 87 Score = 39.5 bits (88), Expect = 0.016 Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 1/38 (2%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLEL-TADKKTCV 604 CA N C LC N P Y C C G EL + D TC+ Sbjct: 49 CATRNNTCEQLCLNHPGHYTCDCRGGYELDSRDNSTCL 86 Score = 36.7 bits (81), Expect = 0.11 Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 3/41 (7%) Query: 568 CADDNG---GCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 CA +NG GC + C N Y C C G LT+D++ C + Sbjct: 5 CAVNNGTTHGCEYRCNNTQGSYKCSCQQGYLLTSDQRHCAD 45 Score = 35.1 bits (77), Expect = 0.34 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 7/50 (14%) Query: 865 NQCGVDNG---GCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 ++C V+NG GC + C T G Y+C+C Y L D C++ +E Sbjct: 3 DECAVNNGTTHGCEYRCNNTQGS----YKCSCQQGYLLTSDQRHCADHDE 48 Score = 34.7 bits (76), Expect = 0.45 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 5/43 (11%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRL-NKDNITC 906 ++C N C LCL PG Y C C Y L ++DN TC Sbjct: 47 DECATRNNTCEQLCLNHPG----HYTCDCRGGYELDSRDNSTC 85 Score = 30.7 bits (66), Expect = 7.4 Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 2/44 (4%) Query: 255 AEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSSTTC 298 A+ C N C LCL P Y C C G +L ++TC Sbjct: 44 ADHDECATRNNTCEQLCLNHPGH--YTCDCRGGYELDSRDNSTC 85 >SB_5319| Best HMM Match : Ldl_recept_a (HMM E-Value=7.56701e-44) Length = 212 Score = 39.1 bits (87), Expect = 0.021 Identities = 33/96 (34%), Positives = 39/96 (40%), Gaps = 32/96 (33%) Query: 1097 CDGQQDCEDGRDEAECG--ACGGD-VRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEG 1153 CDG+ DC D DE +CG +CG D RC++ + RC Sbjct: 134 CDGENDCGDRSDEVDCGLESCGNDRWRCSNTS-----------------------RC--- 167 Query: 1154 LCIAARFVCDGRPQCADGSDEAPAACAYGHTDQVNG 1189 IA VCDGR C D SDE P C NG Sbjct: 168 --IAKSQVCDGRVDCPDASDEGP-GCGLDQCHSNNG 200 Score = 32.7 bits (71), Expect = 1.8 Identities = 14/28 (50%), Positives = 16/28 (57%), Gaps = 1/28 (3%) Query: 1148 FRCD-EGLCIAARFVCDGRPQCADGSDE 1174 F+C+ CI RFVCD C D SDE Sbjct: 79 FQCETSSRCIPLRFVCDADDDCGDRSDE 106 Score = 31.9 bits (69), Expect = 3.2 Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 1/28 (3%) Query: 1148 FRCDEGL-CIAARFVCDGRPQCADGSDE 1174 F C G CI +++CDG C D SDE Sbjct: 119 FACANGRHCIQRKWICDGENDCGDRSDE 146 Score = 30.3 bits (65), Expect = 9.8 Identities = 10/20 (50%), Positives = 14/20 (70%) Query: 863 GSNQCGVDNGGCSHLCLPTP 882 G +QC +NGGC+ LC+ P Sbjct: 191 GLDQCHSNNGGCAQLCMDVP 210 >SB_21284| Best HMM Match : F5_F8_type_C (HMM E-Value=1.8e-21) Length = 564 Score = 38.7 bits (86), Expect = 0.028 Identities = 16/48 (33%), Positives = 22/48 (45%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYS 613 N C + C C N Y C C G +L +DKKTC ++ +S Sbjct: 388 NECVETAHNCQQKCNNDYGSYHCSCDPGFQLNSDKKTCSVIRCYVGFS 435 >SB_27178| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 214 Score = 38.7 bits (86), Expect = 0.028 Identities = 18/39 (46%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLE-LTADKKTC 603 N CA N GC C N Y C C LG + LTA K C Sbjct: 87 NECAQPNHGCQDKCVNTVGSYRCECNLGFKPLTAGSKRC 125 >SB_59441| Best HMM Match : Ldl_recept_b (HMM E-Value=1.4) Length = 57 Score = 38.3 bits (85), Expect = 0.037 Identities = 14/47 (29%), Positives = 30/47 (63%) Query: 327 YTLPLKDLKRTLTVDFDPKTEYIYWADGLAKTISKARLDGSDQSVVV 373 YT ++ L+ T+ +DFD + + +YW+D K IS++ +G+ + ++ Sbjct: 2 YTFAVRRLRNTIGIDFDWREKRLYWSDVYKKVISRSYFNGTGREDLI 48 Score = 30.3 bits (65), Expect = 9.8 Identities = 12/39 (30%), Positives = 20/39 (51%) Query: 684 GLAIDWSGQNIYWTDTTTQRIEVSRLDGSSRRAIIWQGL 722 G+ DW + +YW+D + I S +G+ R +I L Sbjct: 14 GIDFDWREKRLYWSDVYKKVISRSYFNGTGREDLITDAL 52 Score = 30.3 bits (65), Expect = 9.8 Identities = 10/30 (33%), Positives = 19/30 (63%) Query: 773 DYERRAIYWAALDPPVVEFAFLNGTGRQTL 802 D+ + +YW+ + V+ ++ NGTGR+ L Sbjct: 18 DWREKRLYWSDVYKKVISRSYFNGTGREDL 47 >SB_50657| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 442 Score = 38.3 bits (85), Expect = 0.037 Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAACAYGHTDQVNGIHPP 1193 FRC G CI+ VCD C D SDE CA QV+G P Sbjct: 10 FRCANGRCISGALVCDLDDDCGDESDE--RGCAPSAATQVSGRTTP 53 >SB_31927| Best HMM Match : Ldl_recept_a (HMM E-Value=2.3e-27) Length = 157 Score = 38.3 bits (85), Expect = 0.037 Identities = 27/86 (31%), Positives = 30/86 (34%), Gaps = 23/86 (26%) Query: 1097 CDGQQDCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEGLCI 1156 CD DC DG DE C G C G +RCD CI Sbjct: 19 CDKDNDCGDGSDEVACSRLNGGW-CGAGQ----------------------YRCDNDRCI 55 Query: 1157 AARFVCDGRPQCADGSDEAPAACAYG 1182 +VCD C D SDE+ YG Sbjct: 56 PLNWVCDRLNDCHDNSDESGCRGVYG 81 Score = 37.9 bits (84), Expect = 0.049 Identities = 17/33 (51%), Positives = 19/33 (57%), Gaps = 2/33 (6%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAACA 1180 FRC G CI +VCD C DGSDE AC+ Sbjct: 5 FRCRNGNCINRNYVCDKDNDCGDGSDE--VACS 35 >SB_21597| Best HMM Match : ig (HMM E-Value=2.9e-14) Length = 1931 Score = 37.9 bits (84), Expect = 0.049 Identities = 16/41 (39%), Positives = 21/41 (51%) Query: 573 GGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYS 613 GGCS C N Y C C G L D KTC++ F +++ Sbjct: 11 GGCSQSCVNVIGSYYCMCRHGYYLGTDLKTCMKYPCFAIFA 51 Score = 30.3 bits (65), Expect = 9.8 Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 5/53 (9%) Query: 865 NQCGVDN-GGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEEFLLFA 916 ++C + GGCS C+ G Y C C Y L D TC + F +FA Sbjct: 3 DECSLPGPGGCSQSCVNVIGS----YYCMCRHGYYLGTDLKTCMKYPCFAIFA 51 >SB_13504| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 4924 Score = 37.5 bits (83), Expect = 0.064 Identities = 15/38 (39%), Positives = 20/38 (52%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N C +NG C H C N Y C C G +L +++TC Sbjct: 2148 NECERNNGWCEHDCINILGTYRCRCRDGYKLDPNRRTC 2185 Score = 35.1 bits (77), Expect = 0.34 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 4/42 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 N+C +NG C H C+ ++ YRC C Y+L+ + TC Sbjct: 2148 NECERNNGWCEHDCI----NILGTYRCRCRDGYKLDPNRRTC 2185 Score = 30.7 bits (66), Expect = 7.4 Identities = 17/50 (34%), Positives = 23/50 (46%), Gaps = 4/50 (8%) Query: 247 DESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTGVKLRENSST 296 + SR+ I + C++NN C H C+ Y C C G KL N T Sbjct: 2139 NSSRRCIDINE--CERNNGWCEHDCINILGT--YRCRCRDGYKLDPNRRT 2184 >SB_58993| Best HMM Match : EGF_CA (HMM E-Value=0) Length = 541 Score = 37.1 bits (82), Expect = 0.085 Identities = 15/39 (38%), Positives = 18/39 (46%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCV 604 N C C C N Y C CP G ++ ADKK C+ Sbjct: 502 NECEGPTKVCQFDCKNTDGSYECSCPKGYQVDADKKKCL 540 Score = 31.1 bits (67), Expect = 5.6 Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 566 NPCADDNGGC-SHLCFNRPDDYICGCPLGLELTADKKTC 603 N C + G C + C N Y C CP+G T D +C Sbjct: 271 NECVETPGICKTGNCTNIEGSYTCTCPVGYAPTRDSPSC 309 >SB_28492| Best HMM Match : EGF_CA (HMM E-Value=2.2e-15) Length = 89 Score = 37.1 bits (82), Expect = 0.085 Identities = 15/39 (38%), Positives = 18/39 (46%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCV 604 N C C C N Y C CP G ++ ADKK C+ Sbjct: 50 NECEGPTKVCQFDCKNTDGSYECSCPKGYQVDADKKKCL 88 >SB_18810| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 105 Score = 37.1 bits (82), Expect = 0.085 Identities = 16/30 (53%), Positives = 19/30 (63%), Gaps = 1/30 (3%) Query: 1146 DAFRCDEG-LCIAARFVCDGRPQCADGSDE 1174 D F+C +CI + FVCDG P C D SDE Sbjct: 9 DQFQCRASKICIKSSFVCDGVPDCNDHSDE 38 Score = 31.1 bits (67), Expect = 5.6 Identities = 11/21 (52%), Positives = 14/21 (66%) Query: 1155 CIAARFVCDGRPQCADGSDEA 1175 C+ CDG+P C+D SDEA Sbjct: 59 CLNRTLQCDGKPDCSDYSDEA 79 Score = 31.1 bits (67), Expect = 5.6 Identities = 11/17 (64%), Positives = 12/17 (70%) Query: 1096 QCDGQQDCEDGRDEAEC 1112 QCDG+ DC D DEA C Sbjct: 65 QCDGKPDCSDYSDEAHC 81 >SB_56441| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1717 Score = 37.1 bits (82), Expect = 0.085 Identities = 13/23 (56%), Positives = 17/23 (73%) Query: 1093 VSRQCDGQQDCEDGRDEAECGAC 1115 V+ CDG++DC DG DE CG+C Sbjct: 711 VATFCDGKKDCGDGFDETHCGSC 733 Score = 35.9 bits (79), Expect = 0.20 Identities = 13/27 (48%), Positives = 15/27 (55%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 F+C G CI CDG+ C DG DE Sbjct: 701 FQCSSGECIEVATFCDGKKDCGDGFDE 727 Score = 34.7 bits (76), Expect = 0.45 Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%) Query: 1148 FRCDEGLCIAARFVCDG-RPQCADGSDEAPAAC 1179 F C+ G C+ C+G R C DGSDE+ C Sbjct: 664 FTCNNGECVTKTSRCNGMRDSCVDGSDESGCTC 696 >SB_43823| Best HMM Match : MAM (HMM E-Value=0) Length = 1724 Score = 37.1 bits (82), Expect = 0.085 Identities = 16/30 (53%), Positives = 19/30 (63%), Gaps = 1/30 (3%) Query: 1146 DAFRCDEG-LCIAARFVCDGRPQCADGSDE 1174 D F+C +CI + FVCDG P C D SDE Sbjct: 1306 DQFQCRASKICIKSSFVCDGVPDCNDHSDE 1335 Score = 35.9 bits (79), Expect = 0.20 Identities = 15/33 (45%), Positives = 19/33 (57%), Gaps = 1/33 (3%) Query: 1149 RC-DEGLCIAARFVCDGRPQCADGSDEAPAACA 1180 RC + G C+ + VCD C DG+DE P CA Sbjct: 126 RCKNSGHCVQQQQVCDFTDDCGDGTDEDPTLCA 158 Score = 31.5 bits (68), Expect = 4.2 Identities = 12/30 (40%), Positives = 16/30 (53%), Gaps = 4/30 (13%) Query: 1083 DQSAGTVYWAVSRQCDGQQDCEDGRDEAEC 1112 D ++W +CDG+ DC DG DE C Sbjct: 348 DDRCINIFW----KCDGESDCTDGEDEQGC 373 Score = 31.1 bits (67), Expect = 5.6 Identities = 11/21 (52%), Positives = 14/21 (66%) Query: 1155 CIAARFVCDGRPQCADGSDEA 1175 C+ CDG+P C+D SDEA Sbjct: 1356 CLNRTLQCDGKPDCSDYSDEA 1376 Score = 31.1 bits (67), Expect = 5.6 Identities = 11/17 (64%), Positives = 12/17 (70%) Query: 1096 QCDGQQDCEDGRDEAEC 1112 QCDG+ DC D DEA C Sbjct: 1362 QCDGKPDCSDYSDEAHC 1378 >SB_42336| Best HMM Match : Sushi (HMM E-Value=1.5e-08) Length = 303 Score = 36.7 bits (81), Expect = 0.11 Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 566 NPCA-DDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 N C D+NGGC H C N Y C C G +L+ + CV+ Sbjct: 7 NECVLDNNGGCQHFCNNTVGGYQCYCKRGFKLSG-QYHCVD 46 Score = 32.3 bits (70), Expect = 2.4 Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 5/37 (13%) Query: 865 NQCGVDN-GGCSHLCLPTPGDVRTDYRCACPAHYRLN 900 N+C +DN GGC H C T G Y+C C ++L+ Sbjct: 7 NECVLDNNGGCQHFCNNTVG----GYQCYCKRGFKLS 39 Score = 30.7 bits (66), Expect = 7.4 Identities = 13/28 (46%), Positives = 14/28 (50%), Gaps = 2/28 (7%) Query: 263 NNAGCSHLCLLSPDPPGYNCACPTGVKL 290 NN GC H C + GY C C G KL Sbjct: 13 NNGGCQHFC--NNTVGGYQCYCKRGFKL 38 >SB_29580| Best HMM Match : Ldl_recept_a (HMM E-Value=4.2e-38) Length = 130 Score = 36.7 bits (81), Expect = 0.11 Identities = 14/27 (51%), Positives = 15/27 (55%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 FRC+ G CI F CD C D SDE Sbjct: 9 FRCNNGRCITRAFRCDDEDDCLDNSDE 35 Score = 35.9 bits (79), Expect = 0.20 Identities = 15/27 (55%), Positives = 17/27 (62%), Gaps = 1/27 (3%) Query: 1149 RCDEGL-CIAARFVCDGRPQCADGSDE 1174 RCD G C+ +CDG CADGSDE Sbjct: 100 RCDNGSGCVDRMKICDGMRDCADGSDE 126 >SB_33423| Best HMM Match : Ldl_recept_a (HMM E-Value=7.8e-22) Length = 133 Score = 36.3 bits (80), Expect = 0.15 Identities = 21/79 (26%), Positives = 28/79 (35%), Gaps = 2/79 (2%) Query: 1097 CDGQQDCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDE-GLC 1155 CD DC+D RDE C + + F C++ C Sbjct: 43 CDSVADCDDKRDERNC-IPANQIAGLNSKAIEEAKNILQESTVKGGCAEGQFACEKTNKC 101 Query: 1156 IAARFVCDGRPQCADGSDE 1174 +A +CD C DGSDE Sbjct: 102 LAKSSLCDTVHDCDDGSDE 120 Score = 32.3 bits (70), Expect = 2.4 Identities = 13/30 (43%), Positives = 17/30 (56%), Gaps = 1/30 (3%) Query: 1146 DAFRCDEGL-CIAARFVCDGRPQCADGSDE 1174 D +RCD G CI +++CD C D DE Sbjct: 26 DRYRCDNGKKCIPLKWICDSVADCDDKRDE 55 >SB_31087| Best HMM Match : Ldl_recept_a (HMM E-Value=4.2e-32) Length = 1039 Score = 35.9 bits (79), Expect = 0.20 Identities = 21/79 (26%), Positives = 28/79 (35%), Gaps = 2/79 (2%) Query: 1097 CDGQQDCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDE-GLC 1155 CD DC+D RDE C + + F C++ C Sbjct: 856 CDSVADCDDKRDERNC-IPANQIAGLNNKAIEEAKNILQESIVKGGCAEGQFACEKTNKC 914 Query: 1156 IAARFVCDGRPQCADGSDE 1174 +A +CD C DGSDE Sbjct: 915 LAKSSLCDTVHDCDDGSDE 933 Score = 34.3 bits (75), Expect = 0.60 Identities = 25/84 (29%), Positives = 30/84 (35%), Gaps = 21/84 (25%) Query: 1092 AVSRQCDGQQDCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCD 1151 A S CD DC+DG DE C D G+ D F CD Sbjct: 916 AKSSLCDTVHDCDDGSDEKNCPISRRDEEFGCGS--------------------DKFTCD 955 Query: 1152 EGL-CIAARFVCDGRPQCADGSDE 1174 G C+ ++CD C D DE Sbjct: 956 NGAKCLPLTWLCDSITDCMDSKDE 979 Score = 32.3 bits (70), Expect = 2.4 Identities = 13/30 (43%), Positives = 17/30 (56%), Gaps = 1/30 (3%) Query: 1146 DAFRCDEGL-CIAARFVCDGRPQCADGSDE 1174 D +RCD G CI +++CD C D DE Sbjct: 839 DRYRCDNGKKCIPLKWICDSVADCDDKRDE 868 >SB_51630| Best HMM Match : Fz (HMM E-Value=3.3e-34) Length = 1120 Score = 35.5 bits (78), Expect = 0.26 Identities = 14/32 (43%), Positives = 19/32 (59%) Query: 1093 VSRQCDGQQDCEDGRDEAECGACGGDVRCADG 1124 +S+ CDG DC+ G DE +C G + ADG Sbjct: 79 LSKHCDGTWDCQHGTDEMDCQELMGIFQTADG 110 Score = 35.1 bits (77), Expect = 0.34 Identities = 22/73 (30%), Positives = 26/73 (35%), Gaps = 1/73 (1%) Query: 1103 CEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRC-DEGLCIAARFV 1161 C+ G+ E C DV DG+ D F C EG CI Sbjct: 23 CDPGQFECTSSECIPDVLKCDGSEDCADSSDEINCTKRSMCRVDQFECLIEGDCIPLSKH 82 Query: 1162 CDGRPQCADGSDE 1174 CDG C G+DE Sbjct: 83 CDGTWDCQHGTDE 95 >SB_47980| Best HMM Match : EGF_CA (HMM E-Value=7.6e-20) Length = 591 Score = 35.5 bits (78), Expect = 0.26 Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 5/42 (11%) Query: 565 WNPCADDNGGCSHL---CFNRPDDYICGCPLGLELTADKKTC 603 +N C++ + C H C N P Y C CP+G TA+ + C Sbjct: 167 YNECSEQSDECDHTLATCVNTPGSYACACPVG--YTANGRGC 206 Score = 31.1 bits (67), Expect = 5.6 Identities = 15/39 (38%), Positives = 18/39 (46%), Gaps = 7/39 (17%) Query: 865 NQCGVDNGGCSHL---CLPTPGDVRTDYRCACPAHYRLN 900 N+C + C H C+ TPG Y CACP Y N Sbjct: 168 NECSEQSDECDHTLATCVNTPGS----YACACPVGYTAN 202 >SB_13200| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 416 Score = 35.5 bits (78), Expect = 0.26 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 4/63 (6%) Query: 811 ALALFNDSVYWGDWNTGQIQQARKTDGSNRKSIRKDLDYISDLKLYH---RAKSMGSNQC 867 +LA+F D VYW DW G +Q A K G R+ + ++ +L + H R + N+ Sbjct: 17 SLAVFGDHVYWTDWLMG-LQMADKRTGDQRRVLVGKDGHMRNLHVIHALVRPQETSINRT 75 Query: 868 GVD 870 G + Sbjct: 76 GAE 78 >SB_56451| Best HMM Match : EGF (HMM E-Value=0.053) Length = 205 Score = 35.1 bits (77), Expect = 0.34 Identities = 44/167 (26%), Positives = 64/167 (38%), Gaps = 13/167 (7%) Query: 804 DNIPMPYALALFNDSVYWGDWNTGQIQQARKT-DGSNRKSIRKDLDYISDLKLYHRAKSM 862 DN P+ Y+LA D+ + GQ+ T D K + D SD K+M Sbjct: 12 DNRPVTYSLAN-TDAQGYVFTPDGQLNITMTTSDSKTFKFVATDECNASDTTTV-TVKAM 69 Query: 863 GSNQCGVDNGGCSHLCLPTPGDVRTD--YRCACPAHYRLNKDNITCSEPEEFLLFAQKNA 920 +C +GG H P P R Y CACPA + ++ + + L K A Sbjct: 70 ---ECPCQHGGTCH---PHPYHPRGSGQYECACPAGFNGSRCESDIDDCQSSLCVNGKKA 123 Query: 921 VGRIMVANGECNDAYIPLTGLKNVRAIEYDPVEKQLYWMDDDSHSIR 967 R M+A C +P G V + P + + D SI+ Sbjct: 124 KAREMMA--RCLKELLPFIGFTTVCIVTRTPELNRRLAIGDSQPSIK 168 >SB_45647| Best HMM Match : HSP70 (HMM E-Value=0) Length = 1327 Score = 35.1 bits (77), Expect = 0.34 Identities = 17/54 (31%), Positives = 25/54 (46%) Query: 552 MGVKAFRLGAPLGWNPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 +G K GA +G + C +N C C Y C C G L D+++CV+ Sbjct: 281 LGFKRTLEGACVGIDGCVLNNLKCDQRCGFSEQGYSCECVKGYRLAIDRQSCVD 334 Score = 34.3 bits (75), Expect = 0.60 Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 5/55 (9%) Query: 858 RAKSMGSNQCGVDN-GGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSEPEE 911 R + ++C + C + C+ T G Y+C CP YR + D TC + +E Sbjct: 329 RQSCVDIDECSSNQTNSCQYQCINTEGG----YQCKCPPGYRTSPDGRTCMDDDE 379 Score = 33.9 bits (74), Expect = 0.79 Identities = 11/39 (28%), Positives = 19/39 (48%) Query: 569 ADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPE 607 ++ C + C N Y C CP G + D +TC++ + Sbjct: 340 SNQTNSCQYQCINTEGGYQCKCPPGYRTSPDGRTCMDDD 378 >SB_35350| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 626 Score = 35.1 bits (77), Expect = 0.34 Identities = 14/27 (51%), Positives = 17/27 (62%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 F C + CI +R+ CDG CAD SDE Sbjct: 556 FTCADKRCILSRWRCDGDRDCADNSDE 582 Score = 32.7 bits (71), Expect = 1.8 Identities = 21/72 (29%), Positives = 26/72 (36%), Gaps = 6/72 (8%) Query: 1103 CEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEGLCIAARFVC 1162 C D R C GD CAD + ++C G CI +VC Sbjct: 558 CADKRCILSRWRCDGDRDCADNSDEINCPNSSQYCKSSE------YQCSTGECIHKSWVC 611 Query: 1163 DGRPQCADGSDE 1174 DG C + SDE Sbjct: 612 DGEFDCLNKSDE 623 >SB_16935| Best HMM Match : Cadherin (HMM E-Value=0) Length = 2204 Score = 35.1 bits (77), Expect = 0.34 Identities = 13/38 (34%), Positives = 18/38 (47%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 N C+ GC C N Y C C LG +L + ++C Sbjct: 75 NECSQSGHGCEQHCMNTVGSYTCICELGYKLGQNGRSC 112 Score = 31.1 bits (67), Expect = 5.6 Identities = 13/42 (30%), Positives = 19/42 (45%), Gaps = 4/42 (9%) Query: 865 NQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITC 906 N+C GC C+ T G Y C C Y+L ++ +C Sbjct: 75 NECSQSGHGCEQHCMNTVG----SYTCICELGYKLGQNGRSC 112 >SB_21487| Best HMM Match : MAM (HMM E-Value=0) Length = 874 Score = 34.7 bits (76), Expect = 0.45 Identities = 12/29 (41%), Positives = 18/29 (62%) Query: 1146 DAFRCDEGLCIAARFVCDGRPQCADGSDE 1174 ++++C G CI+ +CD C DGSDE Sbjct: 707 ESYKCRSGECISLDLLCDFNKDCLDGSDE 735 >SB_19121| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 229 Score = 34.7 bits (76), Expect = 0.45 Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 2/65 (3%) Query: 81 TDGETNKIEVISIVQKYRKVLFWSEVDLARAIAVVPEDGLMFWTDWGEIPKIERAGMNGD 140 T E E+ + R+ WS+V LA ++++ + FW D +P +R N + Sbjct: 50 TQAEDEDFELGYFGESNRRFTIWSQVQLAEEMSLMKNGKVTFWMD--TMPSKKRKSNNNE 107 Query: 141 PATRK 145 P T K Sbjct: 108 PFTSK 112 >SB_46360| Best HMM Match : EGF (HMM E-Value=0) Length = 352 Score = 33.9 bits (74), Expect = 0.79 Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 8/48 (16%) Query: 256 EDYPCKKNNAGCSHLCLLSPDP-PGYNCACPTGVKLRENSSTTCYDSP 302 E +PC+ NNA C DP GY+C+CPTGV R + C P Sbjct: 167 EAHPCQ-NNATCRM------DPLKGYSCSCPTGVTGRHCDVSICDSKP 207 >SB_6077| Best HMM Match : EGF (HMM E-Value=0) Length = 1165 Score = 33.9 bits (74), Expect = 0.79 Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 8/48 (16%) Query: 256 EDYPCKKNNAGCSHLCLLSPDP-PGYNCACPTGVKLRENSSTTCYDSP 302 E +PC+ NNA C DP GY+C+CPTGV R + C P Sbjct: 980 EAHPCQ-NNATCRM------DPLKGYSCSCPTGVTGRHCDVSICDSKP 1020 >SB_43077| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1149 Score = 33.5 bits (73), Expect = 1.0 Identities = 12/32 (37%), Positives = 16/32 (50%), Gaps = 3/32 (9%) Query: 565 WNPCADDNGGCSHL---CFNRPDDYICGCPLG 593 +N C++ + C H C N P Y C CP G Sbjct: 744 YNECSEQSDECDHTLATCVNTPGSYACACPAG 775 Score = 32.7 bits (71), Expect = 1.8 Identities = 18/62 (29%), Positives = 24/62 (38%), Gaps = 4/62 (6%) Query: 568 CADDNGGCSH--LCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYSRKNIIGRLSIKN 625 C + GC +C N P +IC C G D K C P F G +S+ + Sbjct: 870 CGIGSHGCHSDAICINTPGSFICRCKRG--FGGDGKICYAPFKFTTLGASGRTGPVSLGS 927 Query: 626 EY 627 Y Sbjct: 928 HY 929 Score = 31.9 bits (69), Expect = 3.2 Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 7/39 (17%) Query: 865 NQCGVDNGGCSHL---CLPTPGDVRTDYRCACPAHYRLN 900 N+C + C H C+ TPG Y CACPA Y N Sbjct: 745 NECSEQSDECDHTLATCVNTPGS----YACACPAGYTNN 779 >SB_26647| Best HMM Match : EGF_CA (HMM E-Value=1.1e-05) Length = 120 Score = 33.5 bits (73), Expect = 1.0 Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 4/67 (5%) Query: 549 ANMMGVKAFRLGAPL-GWNPCADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPE 607 +NM+G L PL N C N CS C N Y C C G EL D +C + E Sbjct: 48 SNMIG-DLLALAKPLMNINECQGPNK-CSQGCNNTLGSYSCTCNKGFELGPDNHSC-QGE 104 Query: 608 AFLVYSR 614 L Y R Sbjct: 105 DNLTYCR 111 >SB_2014| Best HMM Match : MAM (HMM E-Value=0) Length = 2282 Score = 33.5 bits (73), Expect = 1.0 Identities = 14/32 (43%), Positives = 16/32 (50%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 F+C G CI+ CDG C D SDE C Sbjct: 214 FQCTSGHCISGSSRCDGDYNCMDRSDEDGCKC 245 Score = 32.7 bits (71), Expect = 1.8 Identities = 15/31 (48%), Positives = 17/31 (54%), Gaps = 2/31 (6%) Query: 1097 CDGQQDCEDGRDEAECG-AC-GGDVRCADGT 1125 CDG +DCE G DE CG C + C D T Sbjct: 264 CDGVRDCEYGLDELRCGDGCKNSEFLCPDST 294 Score = 30.3 bits (65), Expect = 9.8 Identities = 18/69 (26%), Positives = 26/69 (37%), Gaps = 3/69 (4%) Query: 1094 SRQCDGQQDCEDGRDEAECGACGGDVRCADGTXXXXXXXXXXXXXXXXXXXXDAFRCDEG 1153 S +CDG +C D DE C ++ C+ G D RC +G Sbjct: 225 SSRCDGDYNCMDRSDEDGCKCFTNELTCSSG--RCVQSINLCDGVRDCEYGLDELRCGDG 282 Query: 1154 LCIAARFVC 1162 C + F+C Sbjct: 283 -CKNSEFLC 290 >SB_20014| Best HMM Match : EGF_CA (HMM E-Value=1.6e-18) Length = 184 Score = 33.5 bits (73), Expect = 1.0 Identities = 13/29 (44%), Positives = 14/29 (48%) Query: 575 CSHLCFNRPDDYICGCPLGLELTADKKTC 603 C H C N Y C C G L DKK+C Sbjct: 68 CEHQCNNTFGSYSCSCSPGFALADDKKSC 96 >SB_24529| Best HMM Match : Lectin_C (HMM E-Value=3.4e-27) Length = 644 Score = 33.1 bits (72), Expect = 1.4 Identities = 12/39 (30%), Positives = 18/39 (46%), Gaps = 3/39 (7%) Query: 565 WNPCADDNGGCSHL---CFNRPDDYICGCPLGLELTADK 600 +N C++ C H C N P Y C CP G ++ + Sbjct: 375 YNECSEGTDECDHTLATCVNTPGSYTCACPAGYTVSGHR 413 Score = 30.7 bits (66), Expect = 7.4 Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 7/39 (17%) Query: 865 NQCGVDNGGCSHL---CLPTPGDVRTDYRCACPAHYRLN 900 N+C C H C+ TPG Y CACPA Y ++ Sbjct: 376 NECSEGTDECDHTLATCVNTPGS----YTCACPAGYTVS 410 >SB_58994| Best HMM Match : EGF_CA (HMM E-Value=2.3e-29) Length = 309 Score = 32.7 bits (71), Expect = 1.8 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 1/34 (2%) Query: 573 GGCSH-LCFNRPDDYICGCPLGLELTADKKTCVE 605 G C H +C N + C C G LT +K+TCV+ Sbjct: 180 GYCDHGMCKNMNGSFSCVCNQGYHLTDNKRTCVD 213 >SB_4874| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 473 Score = 32.7 bits (71), Expect = 1.8 Identities = 16/49 (32%), Positives = 20/49 (40%), Gaps = 4/49 (8%) Query: 860 KSMGSNQCGVDNGGCSHLCLPTPGDVRTDYRCACPAHYRLNKDNITCSE 908 K + ++CG C H C+ T G Y C C Y L D C E Sbjct: 173 KCVDIDECGSGAARCDHKCVNTEG----SYHCRCRKGYTLAPDGHKCQE 217 Score = 31.5 bits (68), Expect = 4.2 Identities = 14/42 (33%), Positives = 14/42 (33%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVEPEAF 609 C C H C N Y C C G L D C E F Sbjct: 180 CGSGAARCDHKCVNTEGSYHCRCRKGYTLAPDGHKCQEISFF 221 >SB_33986| Best HMM Match : EGF_CA (HMM E-Value=3.5e-17) Length = 85 Score = 32.7 bits (71), Expect = 1.8 Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 573 GGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 G CSH+C N + C C G L D++TC Sbjct: 9 GACSHICQNGYGTFRCICRPGFYLLDDERTC 39 >SB_32491| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 199 Score = 32.7 bits (71), Expect = 1.8 Identities = 13/36 (36%), Positives = 16/36 (44%) Query: 568 CADDNGGCSHLCFNRPDDYICGCPLGLELTADKKTC 603 C +NG C C N YIC C G L + + C Sbjct: 74 CELNNGDCQQSCHNLEGSYICRCNRGYTLLPNGRDC 109 >SB_24583| Best HMM Match : EGF (HMM E-Value=0.74) Length = 266 Score = 32.7 bits (71), Expect = 1.8 Identities = 46/176 (26%), Positives = 71/176 (40%), Gaps = 17/176 (9%) Query: 763 QVGRVHALAIDYERRAIYWAALDPPVVEFAFLNGT-GRQTLA---DNIPMPYALALFNDS 818 Q +H ++ ER+ + ++ +V+FA + Q A DN P+ Y+LA D+ Sbjct: 33 QRASLHGTGLNVERKEPVY--MEQAIVQFALVGEMLSLQIEALDPDNRPVTYSLAN-TDA 89 Query: 819 VYWGDWNTGQIQQARKT-DGSNRKSIRKDLDYISDLKLYHRAKSMGSNQCGVDNGGCSHL 877 + GQ+ T D K + D SD K+M +C +GG H Sbjct: 90 QGYVFTPDGQLNITMTTSDSKTFKFVATDECNASDTTTV-TVKAM---ECPCQHGGTCH- 144 Query: 878 CLPTPGDVRTD--YRCACPAHYRLNKDNITCSEPEEFLLFAQKNAVGRIMVANGEC 931 P P R Y CACPA + ++ + + L K A R M+A C Sbjct: 145 --PHPYHPRGSGQYECACPAGFNGSRFESDIDDCQSSLCVNGKKAKAREMMARCYC 198 >SB_48293| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1135 Score = 31.9 bits (69), Expect = 3.2 Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 441 EKKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTE 498 EKKP++++ +D G VL S K SI + NN+ W + T + ++ G + Sbjct: 371 EKKPEVKQVAVDALGNVLWDSGKYKTKTSITIPCHNNQA-WAELPTEPPAIASVHGLD 427 >SB_47409| Best HMM Match : Ldl_recept_a (HMM E-Value=1.2e-17) Length = 1571 Score = 31.9 bits (69), Expect = 3.2 Identities = 10/18 (55%), Positives = 13/18 (72%) Query: 1096 QCDGQQDCEDGRDEAECG 1113 +C+GQ DC D DE +CG Sbjct: 745 RCNGQMDCRDASDEQDCG 762 >SB_38935| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 281 Score = 31.9 bits (69), Expect = 3.2 Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 4/49 (8%) Query: 568 CADDNGGC--SHLCFNRPDDYICGCPLGLELTADKKTCVEPEAFLVYSR 614 C ++ C + LC N P Y+C C G E D KTC+ +V +R Sbjct: 232 CTNETDDCDANALCTNVPGLYVCRCLRGFE--GDGKTCIRTVNAIVNAR 278 Score = 30.3 bits (65), Expect = 9.8 Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 2/35 (5%) Query: 571 DNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 D+ + LC N P Y+C C G E D KTC++ Sbjct: 73 DDCDANALCTNVPGLYVCRCLKGFE--GDGKTCID 105 Score = 30.3 bits (65), Expect = 9.8 Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 2/35 (5%) Query: 571 DNGGCSHLCFNRPDDYICGCPLGLELTADKKTCVE 605 D+ + LC N P Y+C C G E D KTC++ Sbjct: 155 DDCDANALCTNVPGLYVCRCLKGFE--GDGKTCID 187 >SB_54100| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 3287 Score = 31.9 bits (69), Expect = 3.2 Identities = 12/28 (42%), Positives = 14/28 (50%) Query: 566 NPCADDNGGCSHLCFNRPDDYICGCPLG 593 N CA + C +R D Y C CPLG Sbjct: 743 NDCASNPCAAYQRCIDRIDSYTCACPLG 770 >SB_44255| Best HMM Match : RVT_1 (HMM E-Value=7.6e-29) Length = 1017 Score = 31.9 bits (69), Expect = 3.2 Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Query: 638 KEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIVEWLGLVEGLA 686 + + LA + GS +Y SKT I RC V + V ++ +LG+V +A Sbjct: 495 RSIKFLAHIIDGSGIYVDPSKTDAITRCPV-PTTVTELQRFLGMVNHVA 542 >SB_22727| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 435 Score = 31.9 bits (69), Expect = 3.2 Identities = 13/32 (40%), Positives = 15/32 (46%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 F+C G CI+ CD C D SDE C Sbjct: 280 FQCTSGHCISGSSRCDSDYNCMDSSDEDGCKC 311 Score = 31.9 bits (69), Expect = 3.2 Identities = 11/17 (64%), Positives = 12/17 (70%) Query: 1097 CDGQQDCEDGRDEAECG 1113 CDG +DCE G DE CG Sbjct: 330 CDGVKDCEQGLDELRCG 346 >SB_8478| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1033 Score = 31.9 bits (69), Expect = 3.2 Identities = 11/18 (61%), Positives = 13/18 (72%) Query: 1097 CDGQQDCEDGRDEAECGA 1114 CDG +DCE G DE CG+ Sbjct: 249 CDGVKDCEHGLDELRCGS 266 Score = 30.7 bits (66), Expect = 7.4 Identities = 13/32 (40%), Positives = 15/32 (46%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 F+C G CI+ CD C D SDE C Sbjct: 199 FQCASGHCISGSSRCDSDYNCMDRSDEDGCKC 230 >SB_59402| Best HMM Match : DUF1690 (HMM E-Value=3.4) Length = 339 Score = 31.5 bits (68), Expect = 4.2 Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 442 KKPKIERANLDGSGRVLLISEKLTWPNSIALDTVNNK 478 KKP++E + + LL EK W S++ D NK Sbjct: 177 KKPQVENEGKENVDKKLLTEEKFAWRKSLSEDETENK 213 >SB_32816| Best HMM Match : EGF_CA (HMM E-Value=3.1e-11) Length = 84 Score = 31.5 bits (68), Expect = 4.2 Identities = 11/25 (44%), Positives = 12/25 (48%) Query: 579 CFNRPDDYICGCPLGLELTADKKTC 603 C N P Y+C C G E KTC Sbjct: 17 CVNTPGSYVCKCNSGFEYNPQTKTC 41 >SB_28600| Best HMM Match : EGF_CA (HMM E-Value=4.2e-40) Length = 1042 Score = 31.5 bits (68), Expect = 4.2 Identities = 12/32 (37%), Positives = 15/32 (46%), Gaps = 3/32 (9%) Query: 565 WNPCADDNGGCSHL---CFNRPDDYICGCPLG 593 +N C++ C H C N P Y C CP G Sbjct: 718 YNECSEGTDECDHTLATCVNTPGSYACVCPAG 749 >SB_23501| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 585 Score = 31.5 bits (68), Expect = 4.2 Identities = 11/25 (44%), Positives = 12/25 (48%) Query: 579 CFNRPDDYICGCPLGLELTADKKTC 603 C N P Y+C C G E KTC Sbjct: 56 CVNTPGSYVCKCNSGFEYNPQTKTC 80 >SB_19614| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 603 Score = 31.5 bits (68), Expect = 4.2 Identities = 10/18 (55%), Positives = 13/18 (72%) Query: 1095 RQCDGQQDCEDGRDEAEC 1112 +QC+ +QDC DG DE C Sbjct: 409 KQCNNRQDCRDGSDEISC 426 >SB_18415| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 623 Score = 31.5 bits (68), Expect = 4.2 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 3/44 (6%) Query: 568 CADDNGGCSHLCFNRPDDY-ICGCPLGLELTADKKTCVEPEAFL 610 CA N C H+C + +C C G LT DK++CV+ +L Sbjct: 436 CAKLN--CQHICRESNNGIPMCYCRRGFSLTNDKESCVDVNEYL 477 >SB_55149| Best HMM Match : Ldl_recept_a (HMM E-Value=2.6e-23) Length = 190 Score = 31.5 bits (68), Expect = 4.2 Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 1/28 (3%) Query: 1148 FRC-DEGLCIAARFVCDGRPQCADGSDE 1174 F+C +G CI + CDG C D SDE Sbjct: 95 FKCVSDGKCIPKSWRCDGEMDCPDSSDE 122 >SB_55021| Best HMM Match : EGF_CA (HMM E-Value=1.4013e-45) Length = 348 Score = 31.5 bits (68), Expect = 4.2 Identities = 12/27 (44%), Positives = 15/27 (55%) Query: 579 CFNRPDDYICGCPLGLELTADKKTCVE 605 C N + C C G L+ADKK+C E Sbjct: 237 CSNTQGSFECNCKKGFSLSADKKSCRE 263 >SB_48962| Best HMM Match : Cadherin (HMM E-Value=0) Length = 2225 Score = 31.1 bits (67), Expect = 5.6 Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 3/43 (6%) Query: 260 CKKNNAGCSHL--CLLSPDPPGYNCA-CPTGVKLRENSSTTCY 299 C+ N GC + C SP PGY C P G + + +T C+ Sbjct: 1716 CQDKNRGCGAIQKCATSPCAPGYKCKDFPEGYQCKCVDATKCH 1758 >SB_48794| Best HMM Match : Transposase_5 (HMM E-Value=2.3) Length = 280 Score = 31.1 bits (67), Expect = 5.6 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 9/96 (9%) Query: 617 IIGRLSIKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIV 676 ++ +L+I+ + +K K ++ L VS +K +SD+ + ++ +NG VE Sbjct: 86 VVSKLNIRVQPKRRPQGVKKTKRLNTSKLKVSETKNTFSDTLKQRLDSTLLNGQDVE--T 143 Query: 677 EWLG---LVEGLAIDWSGQNIY----WTDTTTQRIE 705 W G LV A++ GQ I W D + IE Sbjct: 144 AWAGLRELVYNTALECLGQKIRKHKDWFDDNSTEIE 179 >SB_46333| Best HMM Match : EGF (HMM E-Value=1.10001e-40) Length = 580 Score = 31.1 bits (67), Expect = 5.6 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 5/41 (12%) Query: 247 DESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTG 287 D Q+ + PCK NNA C++ D GYNC C G Sbjct: 154 DCETQVKPCDSSPCK-NNATCTN----KEDNSGYNCTCSAG 189 Score = 30.7 bits (66), Expect = 7.4 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 5/41 (12%) Query: 247 DESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTG 287 D Q+ + PCK NNA C++ D YNC C TG Sbjct: 74 DCETQVKPCDTIPCK-NNATCTN----KDDNSSYNCTCSTG 109 Score = 30.3 bits (65), Expect = 9.8 Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 5/37 (13%) Query: 251 QIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTG 287 ++ S + PCK NNA C+ D GYNC C G Sbjct: 38 RVKSCDSSPCK-NNA----TCINKEDNSGYNCTCSAG 69 Score = 30.3 bits (65), Expect = 9.8 Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 5/41 (12%) Query: 247 DESRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTG 287 D Q+ + PCK NNA C+ D GYNC C G Sbjct: 114 DCETQVKPCDSSPCK-NNA----TCINDKDNSGYNCTCSAG 149 >SB_23032| Best HMM Match : RVT_1 (HMM E-Value=1.1e-23) Length = 855 Score = 31.1 bits (67), Expect = 5.6 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 9/96 (9%) Query: 617 IIGRLSIKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIV 676 ++ +L+I+ + +K K ++ L VS +K +SD+ + ++ +NG VE Sbjct: 46 VVSKLNIRVQPKRRPQGVKKTKRLNTSKLKVSETKNTFSDTLKQRLDSTLLNGQDVE--T 103 Query: 677 EWLG---LVEGLAIDWSGQNIY----WTDTTTQRIE 705 W G LV A++ GQ I W D + IE Sbjct: 104 AWAGLRELVYNTALECLGQKIRKHKDWFDDNSTEIE 139 >SB_17635| Best HMM Match : CUB (HMM E-Value=0) Length = 630 Score = 31.1 bits (67), Expect = 5.6 Identities = 12/27 (44%), Positives = 15/27 (55%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 F+CD I ++ CDG C D SDE Sbjct: 422 FKCDNDNYIQCQWKCDGTDDCGDHSDE 448 >SB_58157| Best HMM Match : RVT_1 (HMM E-Value=1.6e-36) Length = 1092 Score = 31.1 bits (67), Expect = 5.6 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 9/96 (9%) Query: 617 IIGRLSIKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIV 676 ++ +L+I+ + +K K ++ L VS +K +SD+ + ++ +NG VE Sbjct: 285 VVSKLNIRVQPKRRPQGVKKTKRLNTRKLKVSETKNTFSDTLKQRLDSTLLNGQDVE--T 342 Query: 677 EWLG---LVEGLAIDWSGQNIY----WTDTTTQRIE 705 W G LV A++ GQ I W D + IE Sbjct: 343 AWAGLRELVYNTALECLGQKIRKHKDWFDDNSTEIE 378 >SB_57293| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1395 Score = 31.1 bits (67), Expect = 5.6 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 9/96 (9%) Query: 617 IIGRLSIKNEYNDAVIPIKDLKEVSALALYVSGSKLYWSDSKTKTINRCSVNGSAVEKIV 676 ++ +L+I+ + +K K ++ L VS +K +SD+ + ++ +NG VE Sbjct: 325 VVSKLNIRVQPKRRPQGVKKTKRLNTSKLKVSETKNTFSDTLKQRLDSTLLNGQDVE--T 382 Query: 677 EWLG---LVEGLAIDWSGQNIY----WTDTTTQRIE 705 W G LV A++ GQ I W D + IE Sbjct: 383 AWAGLRELVYNTALECLGQKIRKHKDWFDDNSTEIE 418 >SB_37757| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 905 Score = 30.7 bits (66), Expect = 7.4 Identities = 12/44 (27%), Positives = 21/44 (47%) Query: 463 KLTWPNSIALDTVNNKLYWGDARTHKIEVCNMDGTERKELHSND 506 KL +P + LD +L D H++ VC+ +G + + D Sbjct: 214 KLLYPGKVCLDGAGRRLVIADTGHHRVIVCSTEGVVHEVIGGED 257 >SB_28272| Best HMM Match : EGF (HMM E-Value=2.6e-15) Length = 157 Score = 30.7 bits (66), Expect = 7.4 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 5/39 (12%) Query: 249 SRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTG 287 S ++ + PC+ NNA C++ D GYNC C TG Sbjct: 74 SARVKPCDSSPCQ-NNATCTN----KEDNSGYNCTCSTG 107 >SB_37171| Best HMM Match : EGF (HMM E-Value=2.6e-15) Length = 186 Score = 30.7 bits (66), Expect = 7.4 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 5/39 (12%) Query: 249 SRQIISAEDYPCKKNNAGCSHLCLLSPDPPGYNCACPTG 287 S ++ + PC+ NNA C++ D GYNC C TG Sbjct: 74 SARVKPCDSSPCQ-NNATCTN----KEDNSGYNCTCSTG 107 >SB_34310| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 1103 Score = 30.7 bits (66), Expect = 7.4 Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 8/89 (8%) Query: 566 NPCADDN-GGCSH--LC-FNRPDDYICGCPLGLELTADKKTCV---EPEAFLVYSRKNII 618 NPC + N GGC +C + P IC CP G +L + C + F+ N Sbjct: 244 NPCHEANQGGCEGRAICVYTGPGKSICKCPPGYKLDESQARCTLCPDGNCFVGCDFYNSE 303 Query: 619 GRLSIKNEYNDAVIPIKDLKEVSALALYV 647 + +E + V+ LK SALA YV Sbjct: 304 ELKTALSEQDSIVLRFAYLK-TSALADYV 331 >SB_28040| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 391 Score = 30.7 bits (66), Expect = 7.4 Identities = 13/32 (40%), Positives = 15/32 (46%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 F+C G CI+ CD C D SDE C Sbjct: 236 FQCASGHCISGSSRCDSDYNCMDRSDEDGCKC 267 >SB_20131| Best HMM Match : RVT_1 (HMM E-Value=0.0049) Length = 186 Score = 30.7 bits (66), Expect = 7.4 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 350 YWADGLAKTISKARL-DGSDQSVVVRSSGVPDSIAIDPLSRKIYWTDPVMDTIN 402 YW + K +++ + DG S V+ +SGVP + PL +Y D + D IN Sbjct: 59 YWLEDFLKNRTQSVVVDGEHSSPVIVTSGVPQGSVVGPLLFLLYIND-LPDGIN 111 >SB_17897| Best HMM Match : Ldl_recept_a (HMM E-Value=1.2e-14) Length = 1217 Score = 30.7 bits (66), Expect = 7.4 Identities = 13/32 (40%), Positives = 15/32 (46%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDEAPAAC 1179 F+C G CI+ CD C D SDE C Sbjct: 1109 FQCASGHCISGSSRCDSDYNCMDRSDEDGCKC 1140 >SB_40813| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 809 Score = 30.3 bits (65), Expect = 9.8 Identities = 13/34 (38%), Positives = 21/34 (61%) Query: 5 SRLTRITTIAKDLEQGTAVDFHYRKNLICWSDQK 38 ++ ++T IA+ LE+G A D K LI W+ +K Sbjct: 548 NKKNKVTMIAEPLEKGLAEDIENEKVLISWNKKK 581 >SB_39600| Best HMM Match : Sushi (HMM E-Value=0) Length = 1368 Score = 30.3 bits (65), Expect = 9.8 Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 8/72 (11%) Query: 874 CSHLCLPTPGDVRTDYRCACPAH--YRLNKDNITC---SEPEEFLLFAQKNAVGRIMVAN 928 C+ C P+ D +++C C Y ++ +TC PE + F N G V Sbjct: 279 CTKACFPSGSDCPPNHKCLCDGQCGYSCVENGLTCGIPEAPENGVRF--YNGTGYNDVVR 336 Query: 929 GECNDAYIPLTG 940 +C+D Y +TG Sbjct: 337 YQCDDNY-TMTG 347 >SB_32754| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 5659 Score = 30.3 bits (65), Expect = 9.8 Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 4/42 (9%) Query: 566 NPCADDNGGC--SHLCFNRPDDYICGCPLGLELTADKKTCVE 605 N C + C + LC N P Y+C C G + D KTC + Sbjct: 624 NECVGSDLLCDPNALCTNTPGSYLCRCKSGFQ--GDGKTCAD 663 >SB_21158| Best HMM Match : Chromo (HMM E-Value=0.00035) Length = 132 Score = 30.3 bits (65), Expect = 9.8 Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 10/81 (12%) Query: 170 VDAK-LQFVDVIDFNGE-KRKRVVKGGL-VYPFALTFSN-------DKLYWTDWQNWSIY 219 +D K L V DFN + +RKR K G VY S DK Y W+NW I+ Sbjct: 11 IDYKALNNVSSADFNFDFQRKRKYKSGSKVYDVERIISQRITSRNGDKEYLVKWKNWPIW 70 Query: 220 TWDIAANGPKIKELIKSHPVP 240 T + + LI+S+ P Sbjct: 71 TSTLEPANHLTEALIRSYLFP 91 >SB_10498| Best HMM Match : Ldl_recept_a (HMM E-Value=2.7e-07) Length = 106 Score = 30.3 bits (65), Expect = 9.8 Identities = 11/27 (40%), Positives = 15/27 (55%) Query: 1148 FRCDEGLCIAARFVCDGRPQCADGSDE 1174 + C +G CI C+G+ C D SDE Sbjct: 9 YECRDGTCIDRNEHCNGKIDCPDASDE 35 Database: nematostella Posted date: Oct 22, 2007 1:22 PM Number of letters in database: 16,821,457 Number of sequences in database: 59,808 Lambda K H 0.319 0.136 0.431 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 41,463,351 Number of Sequences: 59808 Number of extensions: 1783632 Number of successful extensions: 5412 Number of sequences better than 10.0: 130 Number of HSP's better than 10.0 without gapping: 97 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 3654 Number of HSP's gapped (non-prelim): 1072 length of query: 1195 length of database: 16,821,457 effective HSP length: 90 effective length of query: 1105 effective length of database: 11,438,737 effective search space: 12639804385 effective search space used: 12639804385 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.8 bits) S2: 65 (30.3 bits)
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