Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001041-TA|BGIBMGA001041-PA|IPR000873|AMP-dependent
synthetase and ligase, IPR002372|Pyrrolo-quinoline quinone,
IPR011047|Quinonprotein alcohol dehydrogenase-like, IPR009081|Acyl
carrier protein-like, IPR006163|Phosphopantetheine-binding
(758 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q16KQ7 Cluster: AMP dependent ligase; n=1; Aedes aegypt... 292 2e-77
UniRef50_Q7Q0Y5 Cluster: ENSANGP00000006087; n=1; Anopheles gamb... 242 3e-62
UniRef50_Q4RKX3 Cluster: Chromosome 1 SCAF15025, whole genome sh... 173 1e-41
UniRef50_Q4L235 Cluster: 2-aminoadipic 6-semialdehyde dehydrogen... 171 4e-41
UniRef50_Q5RG49 Cluster: Novel AMP-binding enzyme domain contain... 155 3e-36
UniRef50_UPI000155555F Cluster: PREDICTED: similar to putative n... 151 5e-35
UniRef50_A7RVL7 Cluster: Predicted protein; n=1; Nematostella ve... 139 2e-31
UniRef50_UPI0000DB6DE1 Cluster: PREDICTED: similar to 2-aminoadi... 126 2e-27
UniRef50_Q8I104 Cluster: Putative uncharacterized protein; n=3; ... 105 3e-21
UniRef50_Q0DF72 Cluster: Os06g0111600 protein; n=4; Oryza sativa... 101 5e-20
UniRef50_A0UXD2 Cluster: Amino acid adenylation domain; n=1; Clo... 97 2e-18
UniRef50_Q0V991 Cluster: U26 protein; n=11; Tetrapoda|Rep: U26 p... 89 3e-16
UniRef50_O27529 Cluster: Serine/threonine protein kinase related... 89 5e-16
UniRef50_Q6HXY8 Cluster: AMP-binding enzyme; n=10; Bacillus cere... 87 2e-15
UniRef50_A5N8Z4 Cluster: Predicted hybrid nonribosomal peptide s... 87 2e-15
UniRef50_Q12Q14 Cluster: Amino acid adenylation; n=1; Shewanella... 86 3e-15
UniRef50_A3DGP7 Cluster: Amino acid adenylation domain; n=1; Clo... 86 4e-15
UniRef50_A5FI38 Cluster: Amino acid adenylation domain; n=2; Bac... 85 5e-15
UniRef50_A3HT12 Cluster: Non-ribosomal peptide synthase; n=1; Al... 84 1e-14
UniRef50_Q9LTK8 Cluster: Genomic DNA, chromosome 5, BAC clone:F1... 83 3e-14
UniRef50_Q8DTJ5 Cluster: Putative bacitracin synthetase 1; BacA;... 83 4e-14
UniRef50_Q9F9L4 Cluster: Micrococcin P1 peptide synthetase; n=1;... 82 5e-14
UniRef50_A5FI40 Cluster: Amino acid adenylation domain; n=1; Fla... 82 6e-14
UniRef50_A5UMM4 Cluster: Serine/threonine protein kinase related... 82 6e-14
UniRef50_Q3M5N4 Cluster: Amino acid adenylation; n=1; Anabaena v... 81 8e-14
UniRef50_Q63CQ7 Cluster: Multifunctional nonribosomal peptide sy... 80 3e-13
UniRef50_Q63CQ6 Cluster: Multifunctional nonribosomal peptide sy... 80 3e-13
UniRef50_A5UTA8 Cluster: Protein kinase; n=5; Chloroflexi (class... 80 3e-13
UniRef50_Q4C639 Cluster: Amino acid adenylation; n=1; Crocosphae... 79 3e-13
UniRef50_Q8DTJ7 Cluster: Putative surfactin synthetase; n=1; Str... 79 4e-13
UniRef50_A5FI53 Cluster: Amino acid adenylation domain; n=2; Bac... 79 4e-13
UniRef50_UPI00005F995E Cluster: COG1020: Non-ribosomal peptide s... 79 6e-13
UniRef50_Q8XS39 Cluster: Probable non ribosomal peptide syntheta... 77 1e-12
UniRef50_Q3IMN6 Cluster: Predicted cell surface protein/ lipopro... 77 1e-12
UniRef50_Q8CUZ9 Cluster: Monomodular nonribosomal peptide synthe... 77 2e-12
UniRef50_A7BUB2 Cluster: Non-ribosomal peptide synthetase; n=1; ... 77 2e-12
UniRef50_A6VYF8 Cluster: Amino acid adenylation domain; n=1; Mar... 77 2e-12
UniRef50_Q18559 Cluster: Putative uncharacterized protein; n=1; ... 77 2e-12
UniRef50_Q8YTR5 Cluster: Peptide synthetase; n=7; Cyanobacteria|... 76 3e-12
UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7; Pseudomona... 76 3e-12
UniRef50_Q0W5H8 Cluster: Putative uncharacterized protein; n=1; ... 76 3e-12
UniRef50_P39846 Cluster: Peptide synthetase 2; n=5; Bacillus|Rep... 76 3e-12
UniRef50_UPI00015978D8 Cluster: NrsC; n=1; Bacillus amyloliquefa... 76 4e-12
UniRef50_Q12Q13 Cluster: Amino acid adenylation; n=1; Shewanella... 76 4e-12
UniRef50_A3INW9 Cluster: Amino acid adenylation; n=1; Cyanothece... 76 4e-12
UniRef50_Q7MZA9 Cluster: D-alanine-activating enzyme; n=1; Photo... 75 5e-12
UniRef50_A1ZLW0 Cluster: Bacitracin synthetase 1 (BA1), putative... 75 5e-12
UniRef50_A0UXC9 Cluster: Amino acid adenylation domain; n=2; Bac... 75 7e-12
UniRef50_Q2VQ15 Cluster: Nonribosomal peptide synthetase C; n=3;... 75 9e-12
UniRef50_Q84BC8 Cluster: NcpA; n=5; Cyanobacteria|Rep: NcpA - No... 74 1e-11
UniRef50_A3INW7 Cluster: Amino acid adenylation; n=1; Cyanothece... 74 1e-11
UniRef50_Q8TPZ1 Cluster: Cell surface protein; n=1; Methanosarci... 74 1e-11
UniRef50_A0ZL89 Cluster: Non-ribosomal peptide synthase; n=1; No... 74 2e-11
UniRef50_UPI000045BE69 Cluster: COG1020: Non-ribosomal peptide s... 73 3e-11
UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2; Cyanobacte... 73 3e-11
UniRef50_Q7N7D9 Cluster: Similarities with lichenysin synthetase... 73 4e-11
UniRef50_Q6D2G7 Cluster: Putative D-alanine--poly(Phosphoribitol... 73 4e-11
UniRef50_A0UVH5 Cluster: Amino acid adenylation domain; n=2; Bac... 73 4e-11
UniRef50_Q7BQ71 Cluster: Peptide synthetase-like protein; n=1; B... 72 5e-11
UniRef50_A5YBV1 Cluster: Fusaricidin synthetase; n=1; Paenibacil... 72 5e-11
UniRef50_A5FI50 Cluster: Amino acid adenylation domain; n=1; Fla... 72 5e-11
UniRef50_Q8YTR8 Cluster: Peptide synthetase; n=2; Nostocaceae|Re... 72 7e-11
UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomona... 72 7e-11
UniRef50_A7D4L7 Cluster: Pyrrolo-quinoline quinone precursor; n=... 72 7e-11
UniRef50_Q8DTJ8 Cluster: Putative bacitracin synthetase; n=1; St... 71 9e-11
UniRef50_Q7N5R3 Cluster: Complete genome; segment 7/17; n=1; Pho... 71 9e-11
UniRef50_A0UXD7 Cluster: Amino acid adenylation domain; n=1; Clo... 71 9e-11
UniRef50_O68006 Cluster: Bacitracin synthetase 1 (BA1) [Includes... 71 1e-10
UniRef50_Q3M5M7 Cluster: Amino acid adenylation; n=1; Anabaena v... 70 2e-10
UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin s... 70 2e-10
UniRef50_Q4ZT67 Cluster: Amino acid adenylation; n=15; Bacteria|... 70 3e-10
UniRef50_Q6YK39 Cluster: Bacillomycin D synthetase C; n=4; Bacil... 70 3e-10
UniRef50_Q0PH95 Cluster: MassB; n=2; Pseudomonas fluorescens|Rep... 70 3e-10
UniRef50_A1BDX6 Cluster: Amino acid adenylation domain; n=1; Chl... 70 3e-10
UniRef50_P40806 Cluster: Putative polyketide synthase pksJ; n=9;... 70 3e-10
UniRef50_O31782 Cluster: Polyketide synthase of type I; n=2; Bac... 69 4e-10
UniRef50_A3IP47 Cluster: Peptide synthetase; n=2; Cyanobacteria|... 69 4e-10
UniRef50_Q464U3 Cluster: Putative uncharacterized protein; n=2; ... 69 4e-10
UniRef50_Q4C9F4 Cluster: Non-ribosomal peptide synthase:Amino ac... 69 5e-10
UniRef50_Q4C3C3 Cluster: Non-ribosomal peptide synthase:Amino ac... 69 5e-10
UniRef50_Q1Q044 Cluster: Similar to beta-propeller protein YxaL;... 69 5e-10
UniRef50_Q12IB7 Cluster: Amino acid adenylation; n=1; Shewanella... 69 5e-10
UniRef50_A7BRU4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 69 5e-10
UniRef50_A1D5S0 Cluster: Nonribosomal peptide synthase, putative... 69 5e-10
UniRef50_Q12IB9 Cluster: Amino acid adenylation; n=3; cellular o... 69 6e-10
UniRef50_Q110E8 Cluster: Amino acid adenylation domain; n=1; Tri... 69 6e-10
UniRef50_Q3IRQ8 Cluster: Predicted cell surface protein/ lipopro... 69 6e-10
UniRef50_Q89T13 Cluster: Bll2237 protein; n=2; Bradyrhizobium|Re... 68 8e-10
UniRef50_Q63CQ5 Cluster: Multifunctional nonribosomal peptide sy... 68 8e-10
UniRef50_Q8VQF8 Cluster: Peptide synthetase XpsB; n=1; Xenorhabd... 68 8e-10
UniRef50_Q84FL2 Cluster: AdmK; n=2; Gammaproteobacteria|Rep: Adm... 68 8e-10
UniRef50_Q6E7J5 Cluster: JamO; n=1; Lyngbya majuscula|Rep: JamO ... 68 1e-09
UniRef50_A5I518 Cluster: Putative AMP-binding enzyme; n=4; Clost... 68 1e-09
UniRef50_A0UVH3 Cluster: Amino acid adenylation domain; n=1; Clo... 68 1e-09
UniRef50_Q6D9Y3 Cluster: Enterobactin synthetase component F; n=... 67 1e-09
UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3; ... 67 1e-09
UniRef50_Q48D76 Cluster: Non-ribosomal peptide synthetase; n=1; ... 67 1e-09
UniRef50_Q094I7 Cluster: Aminotransferase, class III family; n=9... 67 1e-09
UniRef50_Q8YWC0 Cluster: All1695 protein; n=1; Nostoc sp. PCC 71... 67 2e-09
UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Re... 67 2e-09
UniRef50_Q2VQ17 Cluster: Nonribosomal peptide synthetase A; n=1;... 67 2e-09
UniRef50_Q2ANW8 Cluster: Non-ribosomal peptide synthase:Amino ac... 67 2e-09
UniRef50_Q0S5F4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 67 2e-09
UniRef50_Q0LP26 Cluster: Amino acid adenylation; n=1; Herpetosip... 67 2e-09
UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2; Fir... 67 2e-09
UniRef50_A3INX3 Cluster: Non-ribosomal peptide synthase/polyketi... 67 2e-09
UniRef50_Q95Q02 Cluster: Putative uncharacterized protein; n=2; ... 67 2e-09
UniRef50_Q0LP42 Cluster: Amino acid adenylation; n=1; Herpetosip... 66 3e-09
UniRef50_A6E8C1 Cluster: Amino acid adenylation; n=1; Pedobacter... 66 3e-09
UniRef50_A5FQL9 Cluster: Pyrrolo-quinoline quinone precursor; n=... 66 3e-09
UniRef50_A3INW8 Cluster: Peptide synthetase; n=3; Chroococcales|... 66 3e-09
UniRef50_A1D6D2 Cluster: Nonribosomal peptide synthase GliP2; n=... 66 3e-09
UniRef50_A7IZW1 Cluster: OciA; n=1; Planktothrix agardhii NIVA-C... 66 3e-09
UniRef50_Q97V27 Cluster: Medium-chain-fatty-acid--CoA ligase; n=... 66 3e-09
UniRef50_O68008 Cluster: Bacitracin synthetase 3 (BA3) [Includes... 66 3e-09
UniRef50_Q1D3K7 Cluster: Non-ribosomal peptide synthase; n=1; My... 66 4e-09
UniRef50_A6LQ10 Cluster: Amino acid adenylation domain; n=1; Clo... 66 4e-09
UniRef50_Q13YA9 Cluster: Non-ribosomal peptide synthase, amino a... 65 6e-09
UniRef50_A0ZL90 Cluster: Non-ribosomal peptide synthase; n=1; No... 65 6e-09
UniRef50_Q7N3S1 Cluster: Complete genome; segment 9/17; n=1; Pho... 65 8e-09
UniRef50_Q2L5R6 Cluster: Putative peptide synthetase; n=1; Clost... 65 8e-09
UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8; Ba... 65 8e-09
UniRef50_A5Z788 Cluster: Putative uncharacterized protein; n=1; ... 65 8e-09
UniRef50_A4A1C7 Cluster: Probable serine/threonine protein kinas... 65 8e-09
UniRef50_Q2NHL9 Cluster: Conserved hypothetical membrane-spannin... 65 8e-09
UniRef50_Q0W804 Cluster: Putative uncharacterized protein; n=1; ... 65 8e-09
UniRef50_Q9A9Q2 Cluster: Medium-chain-fatty-acid--CoA ligase; n=... 64 1e-08
UniRef50_Q1Q1C6 Cluster: Putative uncharacterized protein; n=1; ... 64 1e-08
UniRef50_A5FI49 Cluster: Amino acid adenylation domain; n=1; Fla... 64 1e-08
UniRef50_O76858 Cluster: Ebony protein; n=18; Diptera|Rep: Ebony... 64 1e-08
UniRef50_O30409 Cluster: Tyrocidine synthetase 3 (Tyrocidine syn... 64 1e-08
UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C ... 64 1e-08
UniRef50_UPI000038CB2F Cluster: COG1020: Non-ribosomal peptide s... 64 1e-08
UniRef50_Q3M3K2 Cluster: Amino acid adenylation; n=2; Nostocacea... 64 1e-08
UniRef50_Q6E7J8 Cluster: JamL; n=4; Bacteria|Rep: JamL - Lyngbya... 64 1e-08
UniRef50_Q5W263 Cluster: Putative L-prolyl-AMP ligase; n=2; Serr... 64 1e-08
UniRef50_Q1RS73 Cluster: NRPS/PKS protein; n=5; Bacteria|Rep: NR... 64 1e-08
UniRef50_Q0PH94 Cluster: MassC; n=1; Pseudomonas fluorescens|Rep... 64 1e-08
UniRef50_Q5UXV1 Cluster: Putative cell surface protein OR serine... 64 1e-08
UniRef50_Q81DB7 Cluster: Peptide synthetase; n=4; Bacillus cereu... 63 2e-08
UniRef50_Q5WUR2 Cluster: Putative uncharacterized protein; n=2; ... 63 2e-08
UniRef50_Q1D6B8 Cluster: Non-ribosomal peptide synthetase; n=5; ... 63 2e-08
UniRef50_A7BKL9 Cluster: Non-ribosomal peptide synthetase; n=2; ... 63 2e-08
UniRef50_A6EWZ1 Cluster: Peptide synthetase; n=1; Marinobacter a... 63 2e-08
UniRef50_Q8YTR9 Cluster: Peptide synthetase; n=2; Nostocaceae|Re... 63 3e-08
UniRef50_Q8CQA8 Cluster: Surfactin synthetase; n=14; Staphylococ... 63 3e-08
UniRef50_Q5MP00 Cluster: OnnI; n=1; symbiont bacterium of Theone... 63 3e-08
UniRef50_Q0LKI6 Cluster: Amino acid adenylation; n=1; Herpetosip... 63 3e-08
UniRef50_A5Z6T7 Cluster: Putative uncharacterized protein; n=1; ... 63 3e-08
UniRef50_O68007 Cluster: Bacitracin synthetase 2 (BA2) [Includes... 63 3e-08
UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibio... 62 4e-08
UniRef50_A6FDW3 Cluster: Probable peptide synthetase protein; n=... 62 4e-08
UniRef50_A6BZI6 Cluster: Probable serine/threonine protein kinas... 62 4e-08
UniRef50_A0ZF82 Cluster: Non-ribosomal peptide synthase; n=2; No... 62 4e-08
UniRef50_UPI0000DB6BFA Cluster: PREDICTED: similar to ebony CG33... 62 5e-08
UniRef50_UPI000038CDA7 Cluster: COG1020: Non-ribosomal peptide s... 62 5e-08
UniRef50_Q7VUT7 Cluster: Putative D-alanine-D-alanyl carrier pro... 62 5e-08
UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4; Ph... 62 5e-08
UniRef50_Q62C03 Cluster: Nonribosomal peptide synthetase DhbF; n... 62 5e-08
UniRef50_Q4BYH7 Cluster: Thioesterase:Phosphopantetheine-binding... 62 5e-08
UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide syntheta... 62 5e-08
UniRef50_A3KFG5 Cluster: PstC protein; n=2; Actinomycetales|Rep:... 62 5e-08
UniRef50_Q04747 Cluster: Surfactin synthetase subunit 2; n=9; Ba... 62 5e-08
UniRef50_Q311J0 Cluster: Amino acid adenylation; n=2; Bacteria|R... 62 7e-08
UniRef50_Q2AZG3 Cluster: Non-ribosomal peptide synthase:Amino ac... 62 7e-08
UniRef50_Q2AZ45 Cluster: Amino acid adenylation; n=2; Bacillus c... 62 7e-08
UniRef50_Q0YRE6 Cluster: Amino acid adenylation; n=1; Chlorobium... 62 7e-08
UniRef50_Q047K7 Cluster: D-alanine-activating enzyme; n=3; Lacto... 62 7e-08
UniRef50_A5W120 Cluster: Amino acid adenylation domain; n=3; Bac... 62 7e-08
UniRef50_A5FI45 Cluster: Amino acid adenylation domain; n=1; Fla... 62 7e-08
UniRef50_A4D936 Cluster: CrpD; n=2; Nostocaceae|Rep: CrpD - Nost... 62 7e-08
UniRef50_A0V6U3 Cluster: Amino acid adenylation domain; n=1; Del... 62 7e-08
UniRef50_Q08787 Cluster: Surfactin synthetase subunit 3; n=9; Ba... 62 7e-08
UniRef50_P45745 Cluster: Dimodular nonribosomal peptide syntheta... 62 7e-08
UniRef50_UPI0000E46FCE Cluster: PREDICTED: similar to RIKEN cDNA... 61 9e-08
UniRef50_Q8YWG6 Cluster: Peptide synthetase; n=3; Nostocaceae|Re... 61 9e-08
UniRef50_Q8PKR7 Cluster: ATP-dependent serine activating enzyme;... 61 9e-08
UniRef50_Q333V2 Cluster: NRPS protein; n=1; Micromonospora sp. M... 61 9e-08
UniRef50_Q20CI8 Cluster: CesB; n=7; cellular organisms|Rep: CesB... 61 9e-08
UniRef50_Q1RS70 Cluster: Hybrid NRPS/PKS; n=4; cellular organism... 61 9e-08
UniRef50_A3WXS1 Cluster: Probable non-ribosomal peptide syntheta... 61 9e-08
UniRef50_Q2SW14 Cluster: Peptide synthetase, putative; n=1; Burk... 61 1e-07
UniRef50_Q70JX4 Cluster: FenD protein; n=18; Bacillus|Rep: FenD ... 61 1e-07
UniRef50_Q2ANX0 Cluster: Non-ribosomal peptide synthase:Amino ac... 61 1e-07
UniRef50_Q0VZ70 Cluster: Non ribosomal peptide synthase; n=1; Ch... 61 1e-07
UniRef50_Q0LLQ9 Cluster: Amino acid adenylation; n=1; Herpetosip... 61 1e-07
UniRef50_Q9RTJ3 Cluster: Serine/threonine protein kinase-related... 60 2e-07
UniRef50_Q8DTJ6 Cluster: Putative gramicidin S synthetase; n=1; ... 60 2e-07
UniRef50_Q7N5R5 Cluster: Similar to antibiotic synthetase; n=1; ... 60 2e-07
UniRef50_Q8GN23 Cluster: Peptide synthetase; n=1; Fischerella sp... 60 2e-07
UniRef50_Q83Y49 Cluster: Non-ribosomal peptide synthetase; n=2; ... 60 2e-07
UniRef50_Q6VT95 Cluster: Mixed type I polyketide synthase/nonrib... 60 2e-07
UniRef50_Q183T6 Cluster: D-alanine--poly(Phosphoribitol) ligase ... 60 2e-07
UniRef50_Q12HS0 Cluster: Amino acid adenylation; n=1; Shewanella... 60 2e-07
UniRef50_Q091C0 Cluster: Non-ribosomal peptide synthase; n=2; Cy... 60 2e-07
UniRef50_A6T7J0 Cluster: Crotonobetaine/carnitine-CoA ligase; n=... 60 2e-07
UniRef50_A5FI48 Cluster: Amino acid adenylation domain; n=2; cel... 60 2e-07
UniRef50_A4X8R2 Cluster: Amino acid adenylation domain; n=1; Sal... 60 2e-07
UniRef50_Q4ZV21 Cluster: Non-ribosomal peptide synthase:Amino ac... 60 2e-07
UniRef50_Q4KCD8 Cluster: Nonribosomal peptide synthase; n=2; cel... 60 2e-07
UniRef50_Q9F848 Cluster: CmlH; n=1; Streptomyces venezuelae|Rep:... 60 2e-07
UniRef50_Q7WSZ1 Cluster: D-alanine-D-alanyl carrier protein liga... 60 2e-07
UniRef50_Q1GTX6 Cluster: AMP-dependent synthetase and ligase; n=... 60 2e-07
UniRef50_Q0LP45 Cluster: Amino acid adenylation; n=1; Herpetosip... 60 2e-07
UniRef50_Q0LP29 Cluster: Amino acid adenylation; n=1; Herpetosip... 60 2e-07
UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosip... 60 2e-07
UniRef50_A3IZB3 Cluster: Amino acid adenylation; n=2; Chroococca... 60 2e-07
UniRef50_Q0CBA1 Cluster: Predicted protein; n=2; Aspergillus ter... 60 2e-07
UniRef50_Q9HYR8 Cluster: Probable non-ribosomal peptide syntheta... 60 3e-07
UniRef50_Q6LGA3 Cluster: Hypothetical peptide synthetase; n=1; P... 60 3e-07
UniRef50_Q2RJ14 Cluster: AMP-dependent synthetase and ligase; n=... 60 3e-07
UniRef50_Q9Z5F4 Cluster: Ta1; n=4; Bacteria|Rep: Ta1 - Myxococcu... 60 3e-07
UniRef50_Q84BC7 Cluster: NcpB; n=3; Cyanobacteria|Rep: NcpB - No... 60 3e-07
UniRef50_Q0VNL6 Cluster: Non-ribosomal peptide synthase; n=1; Al... 60 3e-07
UniRef50_Q0LLG2 Cluster: Amino acid adenylation; n=1; Herpetosip... 60 3e-07
UniRef50_A3YFF6 Cluster: Amino acid adenylation; n=2; Bacteria|R... 60 3e-07
UniRef50_A2C8M5 Cluster: Putative uncharacterized protein; n=1; ... 60 3e-07
UniRef50_Q2VQ12 Cluster: Nonribosomal peptide synthetase F; n=1;... 59 4e-07
UniRef50_A5MZS0 Cluster: Predicted nonribosomal peptide syntheta... 59 4e-07
UniRef50_A3IZW4 Cluster: Non-ribosomal peptide synthase; n=2; Cy... 59 4e-07
UniRef50_A3I9A7 Cluster: Peptide synthetase; n=1; Bacillus sp. B... 59 4e-07
UniRef50_A0ZF80 Cluster: Peptide synthetase; n=3; Nostocaceae|Re... 59 4e-07
UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3; ... 59 5e-07
UniRef50_Q2Y7Z5 Cluster: Amino acid adenylation; n=2; Nitrosospi... 59 5e-07
UniRef50_Q9K5M1 Cluster: Peptide synthetase; n=8; Bacteria|Rep: ... 59 5e-07
UniRef50_Q4CA71 Cluster: Amino acid adenylation; n=1; Crocosphae... 59 5e-07
UniRef50_Q3WCM4 Cluster: AMP-dependent synthetase and ligase; n=... 59 5e-07
UniRef50_Q0W980 Cluster: Non-ribosomal peptide synthetase; n=2; ... 59 5e-07
UniRef50_A7IZW2 Cluster: OciB; n=1; Planktothrix agardhii NIVA-C... 59 5e-07
UniRef50_A6P624 Cluster: Nonribosomal peptide synthetase; n=1; M... 59 5e-07
UniRef50_A4C4R9 Cluster: Cell surface protein; n=1; Pseudoaltero... 59 5e-07
UniRef50_Q9FDB0 Cluster: Six-domain nonribosomal peptide synthet... 58 7e-07
UniRef50_Q0LN54 Cluster: Amino acid adenylation; n=1; Herpetosip... 58 7e-07
UniRef50_A0ZEC3 Cluster: Beta-ketoacyl synthase; n=26; Cyanobact... 58 7e-07
UniRef50_Q9GSP4 Cluster: Mutant e4 ebony; n=2; Drosophila|Rep: M... 58 7e-07
UniRef50_UPI000045BBC7 Cluster: COG1020: Non-ribosomal peptide s... 58 9e-07
UniRef50_Q8G982 Cluster: Peptide synthetase; n=102; Cyanobacteri... 58 9e-07
UniRef50_Q4C3C0 Cluster: Non-ribosomal peptide synthase:Amino ac... 58 9e-07
UniRef50_Q1ER08 Cluster: Cereulide synthetase 1; n=6; Bacillus|R... 58 9e-07
UniRef50_Q08XI8 Cluster: Beta-lactamase, putative; n=3; Bacteria... 58 9e-07
UniRef50_A6DB12 Cluster: Acyl-CoA synthase; n=1; Caminibacter me... 58 9e-07
UniRef50_A3YFF7 Cluster: Amino acid adenylation; n=1; Marinomona... 58 9e-07
UniRef50_A0ZF81 Cluster: Amino acid adenylation protein; n=3; Ba... 58 9e-07
UniRef50_A0UVJ0 Cluster: Amino acid adenylation domain; n=2; Clo... 58 9e-07
UniRef50_UPI0000DAE7B3 Cluster: hypothetical protein Rgryl_01001... 58 1e-06
UniRef50_UPI0000510064 Cluster: COG1020: Non-ribosomal peptide s... 58 1e-06
UniRef50_Q9I157 Cluster: PvdL; n=23; root|Rep: PvdL - Pseudomona... 58 1e-06
UniRef50_Q81T97 Cluster: D-alanine-activating enzyme/D-alanine-D... 58 1e-06
UniRef50_Q5QVG8 Cluster: Medium-chain acyl-CoA synthetase; n=4; ... 58 1e-06
UniRef50_A4XWA8 Cluster: Amino acid adenylation domain; n=1; Pse... 58 1e-06
UniRef50_A4KVL5 Cluster: Non-ribosomal peptide synthetase module... 58 1e-06
UniRef50_A3YGI9 Cluster: Amino acid adenylation; n=1; Marinomona... 58 1e-06
UniRef50_A1TTJ0 Cluster: Amino acid adenylation domain; n=1; Aci... 58 1e-06
UniRef50_A1FGJ5 Cluster: Amino acid adenylation; n=1; Pseudomona... 58 1e-06
UniRef50_O30408 Cluster: Tyrocidine synthetase 2 (Tyrocidine syn... 58 1e-06
UniRef50_Q9RRI3 Cluster: Medium-chain fatty acid--CoA ligase; n=... 57 2e-06
UniRef50_Q4ZT69 Cluster: Amino acid adenylation; n=8; cellular o... 57 2e-06
UniRef50_Q6WZB2 Cluster: Nonribosomal peptide synthetase; n=1; S... 57 2e-06
UniRef50_Q4CA68 Cluster: Amino acid adenylation; n=1; Crocosphae... 57 2e-06
UniRef50_A6T956 Cluster: Putative acyl-CoA synthase; n=1; Klebsi... 57 2e-06
UniRef50_A6FDW1 Cluster: Surfactin synthetase; n=1; Moritella sp... 57 2e-06
UniRef50_A6EWZ2 Cluster: Beta-ketoacyl synthase; n=1; Marinobact... 57 2e-06
UniRef50_A3I408 Cluster: Long-chain fatty-acid-CoA ligase; n=2; ... 57 2e-06
UniRef50_A1T3J3 Cluster: AMP-dependent synthetase and ligase; n=... 57 2e-06
UniRef50_A1KQR7 Cluster: RhiB protein; n=1; Burkholderia rhizoxi... 57 2e-06
UniRef50_A0V6U0 Cluster: Amino acid adenylation domain; n=1; Del... 57 2e-06
UniRef50_P27206 Cluster: Surfactin synthetase subunit 1; n=15; B... 57 2e-06
UniRef50_Q5M5Z8 Cluster: Non-ribosomal peptide synthetase; n=2; ... 57 2e-06
UniRef50_Q68RS4 Cluster: PrnA; n=1; Prochloron didemni|Rep: PrnA... 57 2e-06
UniRef50_Q0YRE1 Cluster: Amino acid adenylation; n=1; Chlorobium... 57 2e-06
UniRef50_Q0P7K0 Cluster: Putative non-ribosomal peptide synthase... 57 2e-06
UniRef50_A4BLS1 Cluster: Putative non-ribosomal peptide synthase... 57 2e-06
UniRef50_A4ARU6 Cluster: Conserved hypothetical membrane-spannin... 57 2e-06
UniRef50_A3IBP2 Cluster: Peptide synthetase; n=1; Bacillus sp. B... 57 2e-06
UniRef50_A0UXD5 Cluster: Amino acid adenylation domain; n=1; Clo... 57 2e-06
UniRef50_Q9ABN4 Cluster: Medium-chain-fatty-acid--CoA ligase; n=... 56 3e-06
UniRef50_Q2S9J2 Cluster: Non-ribosomal peptide synthetase module... 56 3e-06
UniRef50_Q1D6A0 Cluster: Non-ribosomal peptide synthetase; n=7; ... 56 3e-06
UniRef50_A6CM79 Cluster: O-succinylbenzoic acid--CoA ligase; n=1... 56 3e-06
UniRef50_Q3ITA7 Cluster: Predicted cell surface protein/ lipopro... 56 3e-06
UniRef50_UPI0000DB79A7 Cluster: PREDICTED: similar to CG6178-PA;... 56 4e-06
UniRef50_Q8PKR8 Cluster: ATP-dependent serine activating enzyme;... 56 4e-06
UniRef50_Q89CD3 Cluster: Bll7864 protein; n=15; Bacteria|Rep: Bl... 56 4e-06
UniRef50_Q2SHZ1 Cluster: Non-ribosomal peptide synthetase module... 56 4e-06
UniRef50_A0ZF79 Cluster: Non-ribosomal peptide synthase; n=6; Cy... 56 4e-06
UniRef50_A0UUS4 Cluster: Amino acid adenylation domain; n=1; Clo... 56 4e-06
UniRef50_Q19339 Cluster: Putative uncharacterized protein; n=2; ... 56 4e-06
UniRef50_P26046 Cluster: N-(5-amino-5-carboxypentanoyl)-L-cystei... 56 4e-06
UniRef50_Q4ZV19 Cluster: Non-ribosomal peptide synthase:Amino ac... 56 5e-06
UniRef50_Q83Z53 Cluster: Putisolvin synthetase; n=3; Bacteria|Re... 56 5e-06
UniRef50_Q0LNS7 Cluster: Amino acid adenylation; n=1; Herpetosip... 56 5e-06
UniRef50_A5W126 Cluster: Amino acid adenylation domain; n=2; Pse... 56 5e-06
UniRef50_A3M108 Cluster: Amino acid adenylation; n=2; Bacteria|R... 56 5e-06
UniRef50_A0VFT3 Cluster: AMP-dependent synthetase and ligase; n=... 56 5e-06
UniRef50_Q468K9 Cluster: Cell surface protein; n=1; Methanosarci... 56 5e-06
UniRef50_Q9CHK3 Cluster: 2-succinylbenzoate--CoA ligase; n=3; La... 56 5e-06
UniRef50_Q5ZTD2 Cluster: Acyl CoA ligase; n=4; Legionella pneumo... 55 6e-06
UniRef50_Q3M1N0 Cluster: Amino acid adenylation; n=2; Bacteria|R... 55 6e-06
UniRef50_Q1DCS5 Cluster: Non-ribosomal peptide synthetase; n=1; ... 55 6e-06
UniRef50_Q02HM0 Cluster: Putative non-ribosomal peptide syntheta... 55 6e-06
UniRef50_A6LV83 Cluster: AMP-dependent synthetase and ligase; n=... 55 6e-06
UniRef50_P23971 Cluster: 2-succinylbenzoate--CoA ligase; n=1; Ba... 55 6e-06
UniRef50_Q93GZ7 Cluster: Non-ribosomal peptide synthetase; n=1; ... 55 8e-06
UniRef50_Q881Q3 Cluster: Non-ribosomal peptide synthetase, termi... 55 8e-06
UniRef50_Q9RFK5 Cluster: MtaG; n=4; Cystobacteraceae|Rep: MtaG -... 55 8e-06
UniRef50_Q1GIP8 Cluster: AMP-dependent synthetase and ligase; n=... 55 8e-06
UniRef50_Q0K0K6 Cluster: Non-ribosomal peptide synthetase module... 55 8e-06
UniRef50_A7BXM0 Cluster: Non-ribosomal peptide synthetase; n=2; ... 55 8e-06
UniRef50_A0B7J2 Cluster: Cobaltochelatase precursor; n=1; Methan... 55 8e-06
UniRef50_P38137 Cluster: Peroxisomal-coenzyme A synthetase; n=3;... 55 8e-06
UniRef50_Q2LXW4 Cluster: 2,3-dihydroxybenzoate-AMP ligase; n=1; ... 54 1e-05
UniRef50_Q1D3S3 Cluster: Non-ribosomal peptide synthase; n=3; Ba... 54 1e-05
UniRef50_Q1D3K4 Cluster: Non-ribosomal peptide synthase; n=2; My... 54 1e-05
UniRef50_Q08QA2 Cluster: Linear gramicidin synthetase subunit B;... 54 1e-05
UniRef50_Q8TJS8 Cluster: Cell surface protein; n=1; Methanosarci... 54 1e-05
UniRef50_Q7N4D3 Cluster: Similarities with D-alanine-D-alanyl ca... 54 1e-05
UniRef50_Q4C3C2 Cluster: Amino acid adenylation; n=1; Crocosphae... 54 1e-05
UniRef50_Q211N3 Cluster: Amino acid adenylation; n=1; Rhodopseud... 54 1e-05
UniRef50_A6VVT2 Cluster: AMP-dependent synthetase and ligase; n=... 54 1e-05
UniRef50_A6E8C2 Cluster: Non-ribosomal peptide synthetase/polyke... 54 1e-05
UniRef50_A5L1T1 Cluster: Non-ribosomal peptide synthetase; n=1; ... 54 1e-05
UniRef50_A2R6N2 Cluster: Contig An16c0020, complete genome; n=3;... 54 1e-05
UniRef50_O29570 Cluster: Long-chain-fatty-acid--CoA ligase; n=1;... 54 1e-05
UniRef50_O74976 Cluster: Putative peroxisomal-coenzyme A synthet... 54 1e-05
UniRef50_Q93H04 Cluster: Non-ribosomal peptide synthetase; n=1; ... 54 2e-05
UniRef50_Q62C88 Cluster: Thiotemplate mechanism natural product ... 54 2e-05
UniRef50_Q3M3K1 Cluster: Amino acid adenylation precursor; n=2; ... 54 2e-05
UniRef50_Q5DIP4 Cluster: PvdJ; n=19; root|Rep: PvdJ - Pseudomona... 54 2e-05
UniRef50_Q4H1C8 Cluster: Non-ribosomal peptide synthetase B; n=1... 54 2e-05
UniRef50_A0NLC6 Cluster: Menaquinone biosynthesis O-succinylbenz... 54 2e-05
UniRef50_Q402E3 Cluster: Ebony; n=4; Neoptera|Rep: Ebony - Papil... 54 2e-05
UniRef50_O02200 Cluster: Putative uncharacterized protein; n=3; ... 54 2e-05
UniRef50_Q4J776 Cluster: Acetyl-coenzyme A synthetase; n=2; Sulf... 54 2e-05
UniRef50_UPI000045C11E Cluster: COG1020: Non-ribosomal peptide s... 53 2e-05
UniRef50_Q7N4L0 Cluster: Similar to protein HMWP1 of Yersinia en... 53 2e-05
UniRef50_Q6A878 Cluster: Non-ribosomal peptide synthetase; n=1; ... 53 2e-05
UniRef50_Q6WZA7 Cluster: Nonribosomal peptide synthetase; n=3; A... 53 2e-05
UniRef50_Q50857 Cluster: Saframycin Mx1 synthetase B; n=1; Myxoc... 53 2e-05
UniRef50_Q0VMQ7 Cluster: Peptide synthetase, putative; n=1; Alca... 53 2e-05
UniRef50_A1G7W6 Cluster: Amino acid adenylation domain; n=2; Sal... 53 2e-05
UniRef50_A0V6T7 Cluster: Amino acid adenylation domain; n=2; Com... 53 2e-05
UniRef50_Q6Q883 Cluster: SirP; n=2; Ascomycota|Rep: SirP - Lepto... 53 2e-05
UniRef50_Q93H68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 53 3e-05
UniRef50_Q7N7D7 Cluster: Similarities with probable non-ribosoma... 53 3e-05
UniRef50_Q39GN5 Cluster: Non-ribosomal peptide synthase; n=16; B... 53 3e-05
UniRef50_Q250I2 Cluster: O-succinylbenzoic acid--CoA ligase; n=2... 53 3e-05
UniRef50_Q1D5W2 Cluster: Non-ribosomal peptide synthetase/polyke... 53 3e-05
UniRef50_A1IB03 Cluster: Long-chain-fatty-acid--CoA ligase; n=1;... 53 3e-05
UniRef50_Q8PZ80 Cluster: Long-chain-fatty-acid--CoA ligase; n=4;... 53 3e-05
UniRef50_Q5DIV7 Cluster: PvdI; n=5; Pseudomonas aeruginosa|Rep: ... 52 4e-05
UniRef50_Q4ISP4 Cluster: AMP-dependent synthetase and ligase:Con... 52 4e-05
UniRef50_Q1LMK3 Cluster: AMP-dependent synthetase and ligase; n=... 52 4e-05
UniRef50_Q1D6A2 Cluster: Non-ribosomal peptide synthase; n=1; My... 52 4e-05
UniRef50_Q1D6A1 Cluster: Non-ribosomal peptide synthase/polyketi... 52 4e-05
UniRef50_Q0S3K6 Cluster: Non-ribosomal peptide synthetase; n=2; ... 52 4e-05
UniRef50_Q02HM1 Cluster: Putative non-ribosomal peptide syntheta... 52 4e-05
UniRef50_A4XD37 Cluster: Amino acid adenylation domain; n=2; Sal... 52 4e-05
UniRef50_A1G2S7 Cluster: Amino acid adenylation domain; n=1; Sal... 52 4e-05
UniRef50_Q93H58 Cluster: Non-ribosomal peptide synthetase; n=1; ... 52 6e-05
UniRef50_Q88Z00 Cluster: Non-ribosomal peptide synthetase NpsB; ... 52 6e-05
UniRef50_Q2NDF4 Cluster: AMP-dependent synthetase and ligase; n=... 52 6e-05
UniRef50_Q0RYE3 Cluster: Possible non-ribosomal peptide syntheta... 52 6e-05
UniRef50_A4FD50 Cluster: Non-ribosomal peptide synthase; n=3; Ac... 52 6e-05
UniRef50_Q9C9G2 Cluster: Putative amp-binding protein; 53611-556... 52 6e-05
UniRef50_Q87WM8 Cluster: Non-ribosomal peptide synthetase, initi... 52 8e-05
UniRef50_Q4ZVI3 Cluster: Amino acid adenylation; n=3; Pseudomona... 52 8e-05
UniRef50_Q2SHY7 Cluster: Polyketide synthase modules and related... 52 8e-05
UniRef50_Q2JA66 Cluster: Amino acid adenylation; n=15; Bacteria|... 52 8e-05
UniRef50_Q50JA3 Cluster: Nonribosomal peptide synthetase; n=2; C... 52 8e-05
UniRef50_Q3EYD4 Cluster: Peptide synthetase; n=2; Bacillus thuri... 52 8e-05
UniRef50_Q1IB14 Cluster: Putative non-ribosomal peptide syntheta... 52 8e-05
UniRef50_Q1I8N8 Cluster: Putative pyoverdine sidechain peptide s... 52 8e-05
UniRef50_Q0SK68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 52 8e-05
UniRef50_Q0LPK1 Cluster: Amino acid adenylation; n=1; Herpetosip... 52 8e-05
UniRef50_A4F991 Cluster: Acyl-CoA synthase; n=1; Saccharopolyspo... 52 8e-05
UniRef50_A1ZSB8 Cluster: AMP-dependent synthetase and ligase; n=... 52 8e-05
UniRef50_A1BBQ7 Cluster: AMP-dependent synthetase and ligase; n=... 52 8e-05
UniRef50_A0ITV2 Cluster: Amino acid adenylation domain; n=1; Ser... 52 8e-05
UniRef50_Q60282 Cluster: Uncharacterized protein MJECL23; n=1; M... 52 8e-05
UniRef50_Q81K97 Cluster: 2-succinylbenzoate--CoA ligase; n=17; B... 52 8e-05
UniRef50_Q67T49 Cluster: Medium-chain fatty-acid-CoA ligase; n=2... 51 1e-04
UniRef50_Q3AEI5 Cluster: Medium-chain-fatty-acid--CoA ligase; n=... 51 1e-04
UniRef50_Q2N3S9 Cluster: Hybrid nonribosomal peptide synthetase/... 51 1e-04
UniRef50_Q12RK8 Cluster: Amino acid adenylation; n=1; Shewanella... 51 1e-04
UniRef50_Q0S7I5 Cluster: Non-ribosomal peptide synthetase; n=1; ... 51 1e-04
UniRef50_Q0LUE8 Cluster: AMP-dependent synthetase and ligase; n=... 51 1e-04
UniRef50_Q09E86 Cluster: AMP-binding enzyme domain protein; n=1;... 51 1e-04
UniRef50_Q08Y42 Cluster: AMP-dependent synthetase and ligase; n=... 51 1e-04
UniRef50_A4KUB2 Cluster: TlmVI; n=1; Streptoalloteichus hindusta... 51 1e-04
UniRef50_A1H8X6 Cluster: Medium-chain acyl-CoA ligase; n=5; Bact... 51 1e-04
UniRef50_Q2VJ19 Cluster: Putative nonribosomal peptide synthetas... 51 1e-04
UniRef50_O30043 Cluster: Medium-chain acyl-CoA ligase; n=1; Arch... 51 1e-04
UniRef50_Q88VM6 Cluster: D-alanine--poly(phosphoribitol) ligase ... 51 1e-04
UniRef50_Q666G1 Cluster: Possible high molecular weight sideroph... 51 1e-04
UniRef50_Q2Y7Z2 Cluster: Amino acid adenylation; n=1; Nitrosospi... 51 1e-04
UniRef50_Q18SF0 Cluster: AMP-dependent synthetase and ligase pre... 51 1e-04
UniRef50_O69146 Cluster: Peptide synthetase; n=1; Bacillus subti... 51 1e-04
UniRef50_A6P629 Cluster: Nonribosomal peptide synthetase; n=1; M... 51 1e-04
UniRef50_A5ZLF2 Cluster: Putative uncharacterized protein; n=2; ... 51 1e-04
UniRef50_A4C5W1 Cluster: Non-ribosomal peptide synthetase module... 51 1e-04
UniRef50_A3HT18 Cluster: Putative acyl-CoA synthetase; n=1; Algo... 51 1e-04
UniRef50_A1SI70 Cluster: AMP-dependent synthetase and ligase; n=... 51 1e-04
UniRef50_Q1DST4 Cluster: Putative uncharacterized protein; n=1; ... 51 1e-04
UniRef50_Q9HLJ9 Cluster: Acetyl-CoA synthetase related protein; ... 51 1e-04
UniRef50_Q87WM7 Cluster: Non-ribosomal peptide synthetase, termi... 50 2e-04
UniRef50_Q5ZV98 Cluster: PQQ (Pyrrolo quinoline) WD40-like repea... 50 2e-04
UniRef50_Q8KSQ1 Cluster: Peptide synthetase ScpsA; n=1; Saccharo... 50 2e-04
UniRef50_Q8G983 Cluster: Peptide synthetase; n=118; cellular org... 50 2e-04
UniRef50_Q5ZPA8 Cluster: TubD protein; n=4; cellular organisms|R... 50 2e-04
UniRef50_Q2I765 Cluster: PlaP4; n=9; Bacteria|Rep: PlaP4 - Strep... 50 2e-04
UniRef50_Q0YRD9 Cluster: Amino acid adenylation; n=1; Chlorobium... 50 2e-04
UniRef50_Q07LN1 Cluster: AMP-dependent synthetase and ligase; n=... 50 2e-04
UniRef50_A6LQ14 Cluster: AMP-dependent synthetase and ligase; n=... 50 2e-04
UniRef50_A3Q8J7 Cluster: AMP-dependent synthetase and ligase; n=... 50 2e-04
UniRef50_A2VNP9 Cluster: Fatty-acid-CoA ligase fadD13; n=7; Myco... 50 2e-04
UniRef50_Q4J6T2 Cluster: Medium-chain-fatty-acid-CoA ligase; n=2... 50 2e-04
UniRef50_P42111 Cluster: Uncharacterized protein yxaL; n=1; Baci... 50 2e-04
UniRef50_Q6MLH9 Cluster: Putative lipoprotein; n=1; Bdellovibrio... 50 2e-04
UniRef50_Q5YPH6 Cluster: Putative non-ribosomal peptide syntheta... 50 2e-04
UniRef50_Q50E74 Cluster: Peptide synthetase 1; n=3; Streptomyces... 50 2e-04
UniRef50_Q1D592 Cluster: Non-ribosomal peptide synthase/polyketi... 50 2e-04
UniRef50_Q18ZS4 Cluster: Amino acid adenylation domain; n=2; Des... 50 2e-04
UniRef50_Q0S7E3 Cluster: Synthetase; n=4; Actinomycetales|Rep: S... 50 2e-04
UniRef50_Q0S7A8 Cluster: 2,3-dihydroxybenzoate-AMP ligase/ S-dih... 50 2e-04
UniRef50_A5V240 Cluster: AMP-dependent synthetase and ligase; n=... 50 2e-04
UniRef50_A4KUA9 Cluster: TlmIX; n=2; Actinomycetales|Rep: TlmIX ... 50 2e-04
UniRef50_A1B6F4 Cluster: Amino acid adenylation domain; n=2; Par... 50 2e-04
UniRef50_A0VGY7 Cluster: AMP-dependent synthetase and ligase; n=... 50 2e-04
UniRef50_Q4WZ44 Cluster: Nonribosomal peptide synthase, putative... 50 2e-04
UniRef50_Q8ZV36 Cluster: Acetyl-coenzyme A synthetase; n=4; Pyro... 50 2e-04
UniRef50_Q93H59 Cluster: Non-ribosimal peptide synthetase; n=1; ... 50 3e-04
UniRef50_Q89NI2 Cluster: Bll3856 protein; n=2; Bradyrhizobiaceae... 50 3e-04
UniRef50_Q83DF1 Cluster: Peptide synthetase, putative; n=6; Coxi... 50 3e-04
UniRef50_Q50017 Cluster: XclC; n=4; Actinomycetales|Rep: XclC - ... 50 3e-04
UniRef50_Q13C18 Cluster: AMP-dependent synthetase and ligase; n=... 50 3e-04
UniRef50_Q8L334 Cluster: Peptide synthetase; n=14; Nostocaceae|R... 50 3e-04
UniRef50_Q4J4Y0 Cluster: Amino acid adenylation; n=1; Azotobacte... 50 3e-04
UniRef50_Q2VQ13 Cluster: Nonribosomal peptide synthetase E; n=1;... 50 3e-04
UniRef50_P94873 Cluster: Alpha-aminoadipyl-cysteinyl-valine synt... 50 3e-04
UniRef50_A5FI52 Cluster: AMP-dependent synthetase and ligase; n=... 50 3e-04
UniRef50_A4FC92 Cluster: Acyl-CoA synthase; n=1; Saccharopolyspo... 50 3e-04
UniRef50_A4ABI0 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 50 3e-04
UniRef50_A0QD85 Cluster: AMP-binding enzyme, putative; n=2; Myco... 50 3e-04
UniRef50_A7TCQ0 Cluster: Predicted protein; n=1; Nematostella ve... 50 3e-04
UniRef50_A7SS95 Cluster: Predicted protein; n=1; Nematostella ve... 50 3e-04
UniRef50_Q5D6C7 Cluster: Nonribosomal peptide synthetase 12; n=1... 50 3e-04
UniRef50_Q8YTR4 Cluster: All2649 protein; n=3; Nostocaceae|Rep: ... 49 4e-04
UniRef50_Q4ZVI1 Cluster: Amino acid adenylation; n=12; Bacteria|... 49 4e-04
UniRef50_Q7CT27 Cluster: AGR_L_2309p; n=2; Agrobacterium tumefac... 49 4e-04
UniRef50_Q54297 Cluster: Polyketide synthase; n=8; Streptomyces ... 49 4e-04
UniRef50_Q0SE34 Cluster: Non-ribosomal peptide synthetase; n=1; ... 49 4e-04
UniRef50_Q0SDD1 Cluster: AMP-binding acyl-CoA ligase; n=2; Coryn... 49 4e-04
UniRef50_Q0LN68 Cluster: Amino acid adenylation; n=1; Herpetosip... 49 4e-04
UniRef50_Q0AY10 Cluster: Non-ribosomal peptide synthetase module... 49 4e-04
UniRef50_A6LSE3 Cluster: AMP-dependent synthetase and ligase; n=... 49 4e-04
UniRef50_A3YGJ1 Cluster: Amino acid adenylation; n=1; Marinomona... 49 4e-04
UniRef50_A1WK41 Cluster: AMP-dependent synthetase and ligase; n=... 49 4e-04
UniRef50_A1G504 Cluster: Amino acid adenylation domain; n=1; Sal... 49 4e-04
UniRef50_A0UVH8 Cluster: Amino acid adenylation domain; n=1; Clo... 49 4e-04
UniRef50_Q89DS2 Cluster: Acetyl-coenzyme A synthetase; n=1; Brad... 49 5e-04
UniRef50_Q88JT4 Cluster: Antibiotic biosynthesis protein, putati... 49 5e-04
UniRef50_Q480N6 Cluster: AMP-binding protein; n=1; Colwellia psy... 49 5e-04
UniRef50_Q0RU77 Cluster: 2,3-dihydroxybenzoate-AMP ligase; n=1; ... 49 5e-04
UniRef50_Q0B1F7 Cluster: Amino acid adenylation domain; n=2; Bac... 49 5e-04
UniRef50_A7IJ32 Cluster: Amino acid adenylation domain; n=1; Xan... 49 5e-04
UniRef50_A5EHY6 Cluster: Non-ribosomal peptide synthase; n=2; ce... 49 5e-04
UniRef50_A3IBP6 Cluster: Peptide synthetase; n=1; Bacillus sp. B... 49 5e-04
UniRef50_A3DGP4 Cluster: Amino acid adenylation domain; n=1; Clo... 49 5e-04
UniRef50_A0Y2S2 Cluster: Acyl-CoA synthase; n=1; Alteromonadales... 49 5e-04
UniRef50_A7E7I7 Cluster: Putative uncharacterized protein; n=1; ... 49 5e-04
UniRef50_Q46BK7 Cluster: Cell surface protein; n=1; Methanosarci... 49 5e-04
UniRef50_Q89Y48 Cluster: Blr0107 protein; n=7; Alphaproteobacter... 48 7e-04
UniRef50_Q4KES9 Cluster: Nonribosomal peptide synthetase; n=6; B... 48 7e-04
UniRef50_Q13PB0 Cluster: Putative acid-CoA ligase; n=1; Burkhold... 48 7e-04
UniRef50_Q0LIS9 Cluster: Amino acid adenylation; n=1; Herpetosip... 48 7e-04
UniRef50_A4ZPY4 Cluster: DepD; n=3; Chromobacterium violaceum|Re... 48 7e-04
UniRef50_A4AIZ3 Cluster: O-succinylbenzoate-CoA ligase; n=1; mar... 48 7e-04
UniRef50_A3PQM5 Cluster: AMP-dependent synthetase and ligase; n=... 48 7e-04
UniRef50_Q64CN3 Cluster: Serine/threonine protein kinase related... 48 7e-04
UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular... 48 0.001
UniRef50_Q98JF4 Cluster: Peptide synthetase; n=1; Mesorhizobium ... 48 0.001
UniRef50_Q3JQV3 Cluster: Nonribosomal peptide synthetase; n=24; ... 48 0.001
UniRef50_Q0GL78 Cluster: AMP-binding enzyme; n=3; Lactobacillus ... 48 0.001
UniRef50_Q01XX1 Cluster: Pyrrolo-quinoline quinone precursor; n=... 48 0.001
UniRef50_A6Q2E0 Cluster: Long-chain fatty-acid-CoA ligase; n=8; ... 48 0.001
UniRef50_A4ZPY5 Cluster: DepE; n=2; cellular organisms|Rep: DepE... 48 0.001
UniRef50_A4KVL6 Cluster: Non-ribosomal peptide synthetase module... 48 0.001
UniRef50_A1UD40 Cluster: AMP-dependent synthetase and ligase; n=... 48 0.001
UniRef50_Q54WL7 Cluster: Putative uncharacterized protein; n=1; ... 48 0.001
UniRef50_Q70LM7 Cluster: Linear gramicidin synthetase subunit A ... 48 0.001
UniRef50_Q5KY15 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 48 0.001
UniRef50_Q47C79 Cluster: AMP-dependent synthetase and ligase; n=... 48 0.001
UniRef50_Q8VQF9 Cluster: Peptide synthetase XpsA; n=1; Xenorhabd... 48 0.001
UniRef50_Q4C7P5 Cluster: AMP-dependent synthetase and ligase:Acy... 48 0.001
UniRef50_Q1JI24 Cluster: Long-chain-fatty-acid--CoA ligase; n=11... 48 0.001
UniRef50_Q1DBW4 Cluster: Non-ribosomal peptide synthetase; n=3; ... 48 0.001
UniRef50_Q11F62 Cluster: Amino acid adenylation domain; n=1; Mes... 48 0.001
UniRef50_Q11CG1 Cluster: AMP-dependent synthetase and ligase; n=... 48 0.001
UniRef50_Q0S0V4 Cluster: Possible CoA-dependent ligase; n=1; Rho... 48 0.001
UniRef50_A5XI24 Cluster: Non-ribosomal peptide synthase; n=23; B... 48 0.001
>UniRef50_Q16KQ7 Cluster: AMP dependent ligase; n=1; Aedes
aegypti|Rep: AMP dependent ligase - Aedes aegypti
(Yellowfever mosquito)
Length = 933
Score = 292 bits (717), Expect = 2e-77
Identities = 228/791 (28%), Positives = 384/791 (48%), Gaps = 68/791 (8%)
Query: 1 MVEILLACTNGASLLI--------APDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIK 52
+V++ LA N A L++ A L V+F + VT Q TPS Q ++ I+
Sbjct: 173 VVDMFLALRNAACLVLVGNELRLDAGRLQRVVFEQ---TEVTVMQMTPSFLRQWNDNEIR 229
Query: 53 NKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNK 112
+ +L S+L+ L LGGEP LK H + +++ +YG+TE+SCWAS+ + +
Sbjct: 230 DVLLGRSSSLRHLILGGEPFPSW--LKIPAH--SPVKVYNIYGITEVSCWASIERVTASS 285
Query: 113 VTTGDKEVPLGNCLSETELFVQP-HEKN--NTM----GKIILASKTRKCILLNRKNGNKE 165
PL + + V H N N + G + + S RKCI+ + +
Sbjct: 286 NINPSLGSPLDDSIVFQLRDVNTGHALNLENVVDPIRGNLHIGSGVRKCIIGEESSEDVL 345
Query: 166 E-NSIKFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV-RSCSC 222
++I + TGD+ E R+ G +Y GR D+++KR G ++NL +E QC + +SC+
Sbjct: 346 RIDAIVYRSTGDLVEQRSDGKFYYLGRCDESVKRLGVRVNLSWLEQCADQCEGILKSCAI 405
Query: 223 VWLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
+ + + Y S+ + ++ F++ KL + P+ ++V LP + HGK +++ ++
Sbjct: 406 FDPRRHRIALCYTSSGIVQKNDIRTFMESKLKSEEMPNDFLQVKELPLSDHGKINRKKIL 465
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SK--------SFFSLGGTSFLA 333
+ + N + +N+K + + L+ L SK SF +GGTS A
Sbjct: 466 EQFLEDNDSKPTKNLKEQFLRNVFELLGVHLQARSTSYSKRVKYDLGCSFLDVGGTSVQA 525
Query: 334 VTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQDTNCLENKFKKSIKRNRSTSSH 393
+ I L ++ LL + + DVL+ LE R+ + SS
Sbjct: 526 LQISASLQDYTKTRISSLIGMLLDKSVPLKDVLQY-------LEGV------RHETPSSS 572
Query: 394 GENSISYKKGAGGIRNSNTVEFVVQWTFDTGKCVDASPALYKSESVL--YVTVGSHSGKI 451
S+S ++ ++ VQ FD KC+DASP Y+SE V VGSHS K+
Sbjct: 573 SLQSVSSEENT-----LLKMKITVQSHFDMDKCIDASPTEYRSEKHKRGIVAVGSHSHKL 627
Query: 452 VVMNANTGFIQGLIKLKSRIEAPILCVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQI 511
+V+N T I + L RIE+ + + DE G++G YDG++ CF L ++ W
Sbjct: 628 LVLNTETDQIITQLVLPDRIESAVSYIADE----ERGLIGCYDGSLYCFDLWTGAIRWSF 683
Query: 512 NVGSMIKSKATYCKGVLYIASY--DGNIRCIDILTSTIKETVHVSDQAISADLVLAKNEF 569
+ G MIK KA + + SY + N+ +D+ I + + + I + + +E
Sbjct: 684 DSGGMIKCKALVLESAVIFGSYAEEHNLFALDLNGILIWRS-KLGTKGILSSPLSTDHER 742
Query: 570 ILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKG 629
TL G+ C + T ++W+ L+ P+FA L V+ AEV G +HC + G
Sbjct: 743 AFVATLDGLYCCFNTRTGAVVWEDKLQTPVFANTTLVSGHNAVLVAEVKGILHCLASKSG 802
Query: 630 IKIWTYNGAKGNIFSSLCVKEINKFKW-QMYFGCHDNNVYSVNIT---NFQPSLHWKTRV 685
K+W +GN+FSS V + + ++ FGCHD ++Y + T + P L WK +
Sbjct: 803 SKLWQIR-TEGNLFSSPQVTPCDSNQTVEILFGCHDKHLYCYDWTGKYSENPFLKWKLLL 861
Query: 686 SSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHV-FIG 744
SP+Y+TP+I N ++ ST G + ++ GT+ +L GE FSSP+ D +V ++G
Sbjct: 862 QSPIYATPSIANGSAVV-CSTSGWVNLVCLLSGTIVGLLKLTGEVFSSPLFVDTNVIYVG 920
Query: 745 CRNDLLYSLKI 755
CR++ LY + +
Sbjct: 921 CRDNNLYKITV 931
>UniRef50_Q7Q0Y5 Cluster: ENSANGP00000006087; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000006087 - Anopheles gambiae
str. PEST
Length = 824
Score = 242 bits (592), Expect = 3e-62
Identities = 206/768 (26%), Positives = 372/768 (48%), Gaps = 77/768 (10%)
Query: 33 VTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFT 92
+TF Q TPS F + S ++ + I ++TL+ L LGGE + + + + ++
Sbjct: 91 ITFMQMTPSMFTRWSKTDMLDIIFGPQTTLRTLVLGGERFPVLP-----RAADCRVSVYN 145
Query: 93 LYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELF-----VQPHEKNNT-MGKII 146
+YG+TE+SCW+ + ++ T ++PLG L ++ + + H N + +G++
Sbjct: 146 IYGITEVSCWSMIQKVQSQDNQT---DIPLGEVLDQSIVLQIRNEIDDHLANGSKIGQLY 202
Query: 147 LASKTRKCILLNRKNGNKEENS---IKFIDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKI 202
+ S +RKC++L + ++ + F TGD+ E+ + G +YRGR TIKRFG +I
Sbjct: 203 IGSCSRKCVILGMSEDDDTLSTMPDVVFRATGDLVELSKEGNYYYRGRCSRTIKRFGCRI 262
Query: 203 NLHSIESTVMQCPRVRSCSCVWLQTPLLLIVYFSAETLSS---QELLDFLKCKLDEKYWP 259
+L +E+ + P V C+ +++ L++YF+++T S + L ++ KL + P
Sbjct: 263 SLPELEAVLQTHPSVEQCASCFIEELNRLVIYFTSDTDDSSLREALWSIMRAKLRAEMLP 322
Query: 260 DKVIRVDTLPTNAHGKTSKEILVNIY---KKSNILQNVENIKSYLFKELKA--LVNKDLN 314
D++ R++ P +AHGK + L I+ K+S I + + + Y EL A +V++
Sbjct: 323 DELHRIEQFPLSAHGKICPKGLGVIFENLKQSRIKECITPV-DYFCAELNAMGIVHESQP 381
Query: 315 YEDLQSK------SFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKT 368
E ++K SF GGTSF A IC L T E K LP L++ + D L
Sbjct: 382 IESGRTKKLKPNSSFMDRGGTSFNA--IC--LHATLEEHFKIQLPGLMA---LLLDPLIP 434
Query: 369 ITQDTNCLENKFKKSIKRNRSTSSHGENSISYKKGAGGIRNSNTVEFVVQWTFDTGKCVD 428
+ + + +++K S S+ ++ ++ I+N ++ +D KC+D
Sbjct: 435 LEKAIDYIQSKIA------TSNSNCLQDDVT-------IQNPAEKLLSIERQYDLKKCID 481
Query: 429 ASPALYKSESV-LYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCVHDECVTSPC 487
+ ++ + + ++VGSH+G +V +N T I RIE + E +
Sbjct: 482 SRASIIYCQGIGAILSVGSHAGLLVTINIETNAIISHHLFPDRIECSVNFFTFE--ANVY 539
Query: 488 GVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYC--KGVLYIASYD--GNIRCIDIL 543
G+VG YDG + CF V W+ + G MIK V+ SY N+ CI +
Sbjct: 540 GIVGCYDGFLYCFNPWK-GVAWKYDAGGMIKCAPLVVPQTNVIIFGSYSTTNNLHCIAGV 598
Query: 544 TSTIKE-TVHVSDQAISAD-LVLAKN--EFILFGTLSGVCACLHVNTKTIIWQGSLKG-- 597
TI + + + + I +VL ++ EF+L TL G A + + T + W+ + +
Sbjct: 599 RHTITQWIIRIGTKPILCQPIVLGEDGAEFVLVATLDGTIASISIATGCLAWKRTTQRSV 658
Query: 598 PIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQ 657
PIF+ P L + V+G + ++G ++ T + GN+FSSL + + +
Sbjct: 659 PIFSTPTLLPEYNKIACCSVDGTLGIYETKQGTEL-TIHSLPGNVFSSLVMLKYALDRVD 717
Query: 658 MYFGCHDNNVYSVNITNFQPSL---HWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIH 714
GC+D +V+ V + WK V S +Y+TP + L++ +T G + +I
Sbjct: 718 FIVGCYDRHVHCVEYLPANSNTLIPKWKIEVQSQIYATPLLVEGYLVV-CTTSGWINLID 776
Query: 715 SE-----LGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKIDT 757
+ ++ + +L GE F+SP+ VF GCR++ LY + ++T
Sbjct: 777 TRDSSDAKNSIISSMKLNGELFASPVGYGKKVFFGCRDNFLYEILLNT 824
>UniRef50_Q4RKX3 Cluster: Chromosome 1 SCAF15025, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 1
SCAF15025, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 850
Score = 173 bits (422), Expect = 1e-41
Identities = 194/826 (23%), Positives = 344/826 (41%), Gaps = 98/826 (11%)
Query: 1 MVEILLACTNGASLLIAPDLTE-----VLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKI 55
+V++ LA ++GA LL+ P + + + + T Q TP+ + +K ++
Sbjct: 49 VVDMFLALSSGAQLLVVPSVLKQTPGRLARRLFQRHKTTVMQVTPTLLTRFGQRTLKQEV 108
Query: 56 LCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWAS---VAELDLNK 112
L + S L+VLALGGE +L+ + ++N+T ++ +YG+TE+SCWA + E L
Sbjct: 109 LSSASPLRVLALGGEACPPPALLRSWRQEHNRTSVYNIYGITEVSCWACCHRIPESLLQS 168
Query: 113 VTTGDKEVPLGNCLSETELFVQPHEKNNTM---GKIILASKTRKCILLNRKNGNKEENSI 169
+ VPLG L +T + V+ E G++ + + R C+L + EE +
Sbjct: 169 PAHAESFVPLGAPLMDTRVEVRDDEGGLVTEGEGQVFIGGEERVCLL------DLEETVV 222
Query: 170 K--FIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS-CVWLQ 226
+GD +R + Y GR D +KR G ++NL S++ ++ P+V +C+ C+
Sbjct: 223 PGTMRASGDWVRVRGEELEYLGRRDRLVKRHGKRVNLDSLQQLILGLPQVDACAVCLHEG 282
Query: 227 TPLLLIVYFSAETLSSQE--------------------------LLDFLKCKLDEKYWPD 260
LL V S Q +LD L L PD
Sbjct: 283 LRLLAFVVPSRNQAVQQRRDPPEPPPPSGTEGTADGTDGRLRRLILDQLSLLLPSHSVPD 342
Query: 261 KVIRVDTLPTNAHGKTSKEILVNIYKK------------SNILQNVENIKSYLFKELKAL 308
++ + L HGK E LV ++ SN+ Q VE + L
Sbjct: 343 TLLLIPALLLTPHGKVDTEALVRTFQTQRKRLCPSPGDASNLRQAVELLWQLAVCGQDVL 402
Query: 309 -VNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLK 367
+ +D+ E+ + SF S GG S A+ +C + +L LL + + DVL
Sbjct: 403 GLPEDVPVEE--NSSFLSSGGDSLKALRLCEDILTATGAASADLLEVLL--DGTFSDVLS 458
Query: 368 TITQDTNCLENKFKKSIKRNRSTSSHGENSISYKKGAGGIRNSNTVEFVVQWTFDTGKCV 427
+ + ++ K +KR S K+ A + V+ G+ V
Sbjct: 459 HVERAARGATSE-KGPLKRRSDVPSAAPGKRERKQSAAAEER-----WAVKVVRRAGEVV 512
Query: 428 DASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCVHDECVTSP- 486
D S S G ++ ++ + G + +P+L V SP
Sbjct: 513 DVSIPETTVPDDARKQNPSRGGGVLDLSLSWASDTG----RCVDASPLLLVRYRGEQSPQ 568
Query: 487 ----CGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATY--CKGVLYIASYDGNIRCI 540
++G++ + L + S++W+ +G I++ A C ++ + YD + +
Sbjct: 569 EGRATVIIGSHSHRIQALDLLSGSLVWERVLGGRIEASAAVSPCGSLVVVGCYDSCVYFL 628
Query: 541 DILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSG-VCACLHVNTKTIIWQGSLKGPI 599
+ + D S+ V + ++ G+ G V A ++ ++W P
Sbjct: 629 CASSGDTRWIFKTGDAVKSSPAVDPVSGLVMVGSHDGSVYALDPEDSGEVLWSYRRDAPF 688
Query: 600 FACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMY 659
F+ P + V+ V+G I C + G +W + G +FSS CV ++ ++
Sbjct: 689 FSSP--NGSTGRVLIGSVDGNICCLS-SAGELMWEFL-TNGPVFSSPCVWADHR---RVL 741
Query: 660 FGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDK-------LILAASTDGKLWV 712
G HD +Y ++ SL W + V+S+P +F+ L+ STDG +W+
Sbjct: 742 CGSHDGCLYCLSADG---SLVWSFQTPGKVFSSPCVFDGSAVGRRGALVGLVSTDGTVWI 798
Query: 713 IHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKIDTK 758
+ G A + L GE FSSP++ + +GCR+D +Y LK+ K
Sbjct: 799 LDGRDGRTLASFTLKGELFSSPLVWRRSLVVGCRDDFVYCLKLAVK 844
>UniRef50_Q4L235 Cluster: 2-aminoadipic 6-semialdehyde dehydrogenase;
n=25; Amniota|Rep: 2-aminoadipic 6-semialdehyde
dehydrogenase - Homo sapiens (Human)
Length = 1098
Score = 171 bits (417), Expect = 4e-41
Identities = 115/359 (32%), Positives = 180/359 (50%), Gaps = 35/359 (9%)
Query: 413 VEFVVQWTFDTGKCVDASPALY-----KSESVLYVTVGSHSGKIVVMNANTGFIQGLIKL 467
+E V+W DTGKCVDASP + KS + +Y+ GSHS ++ ++ +G ++ L
Sbjct: 753 MELHVRWRSDTGKCVDASPLVVIPTFDKSSTTVYI--GSHSHRMKAVDFYSGKVKWEQIL 810
Query: 468 KSRIEAPILCVHDECVTSPCG---VVGTYDGTVICFLLENCSVIWQINVGSMIKSKATY- 523
RIE+ CV S CG VVG Y+G V + W +KS AT
Sbjct: 811 GDRIES------SACV-SKCGNFIVVGCYNGLVYVLKSNSGEKYWMFTTEDAVKSSATMD 863
Query: 524 -CKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACL 582
G++YI S+D + +DI S+ + + F TL G+ +
Sbjct: 864 PTTGLIYIGSHDQHAYALDIYRKKCVWKSKCGGTVFSSPCLNLIPHHLYFATLGGLLLAV 923
Query: 583 HVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNI 642
+ T +IW+ S P+F+ P +Y+ V+G + C T G ++W ++ G I
Sbjct: 924 NPATGNVIWKHSCGKPLFSSPQCCS--QYICIGCVDGNLLCFT-HFGEQVWQFS-TSGPI 979
Query: 643 FSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIF------ 696
FSS C + +++FG HD +Y N+ L WK +S VY+TP F
Sbjct: 980 FSSPCTSPSEQ---KIFFGSHDCFIYCCNMKGH---LQWKFETTSRVYATPFAFHNDNGS 1033
Query: 697 NDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKI 755
N+ L+ AASTDGK+W++ S+ G + + Y+LPGE FSSP++ + + IGCR++ +Y L +
Sbjct: 1034 NEMLLAAASTDGKVWILESQSGQLQSVYELPGEVFSSPVVLESMLIIGCRDNYVYCLDL 1092
Score = 171 bits (416), Expect = 6e-41
Identities = 175/780 (22%), Positives = 327/780 (41%), Gaps = 52/780 (6%)
Query: 1 MVEILLACTNGASLLIAPDLTEVLFHE-----DNDNSVTFWQTTPSKFFQHSNENIKNKI 55
+VEI LA ++GASLLI P ++L + + + VT Q TP+ + ++ IK+ +
Sbjct: 246 VVEIFLALSSGASLLIVPTSVKLLPSKLASVLFSHHRVTVLQATPTLLRRFGSQLIKSTV 305
Query: 56 LCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWAS---VAELDLNK 112
L A ++L+VLALGGE + +L+ + + NKT+IF +YG+TE+S WA+ + E LN
Sbjct: 306 LSATTSLRVLALGGEAFPSLTVLRSWRGEGNKTQIFNVYGITEVSSWATIYRIPEKTLNS 365
Query: 113 VTTGDKEVPLGNCLSETELFVQPHEK---NNTMGKIILASKTRKCILLNRKNGNKEENSI 169
+ V LG L T + V+ G++ L + R C L + ++
Sbjct: 366 TLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFLGGRNRVCFLDDEV--TVPLGTM 423
Query: 170 KFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL 229
+ TG +++G +F+ GR D IKR G ++N+ ++ + +V SC+ W
Sbjct: 424 R--ATGGFVTVKDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESCAVTWYNQEK 481
Query: 230 LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSN 289
L++ S + + + L+ L PD+++ +D+LP +HGK L IY
Sbjct: 482 LILFMVSKDASVKEYIFKELQKYLPSHAVPDELVLIDSLPFTSHGKIDVSELNKIYLNYI 541
Query: 290 ILQNVENI--KSYLFKELKALVNKDLNY-EDL----QSKSFFSLGGTSFLAVTICNKLSL 342
L++ + K L+++L+ L LN EDL F + GG S ++ + +++
Sbjct: 542 NLKSENKLSGKEDLWEKLQYLWKSTLNLPEDLLRVPDESLFLNSGGDSLKSIRLLSEIEK 601
Query: 343 TFPEVGKHILPHLLSHN--KSIGDVLKTITQDTNCLENKFKKSIKRNRSTSSHGENSISY 400
+L +LS + + +L+T+ D + F+KS R S + S
Sbjct: 602 LVGTSVPGLLEIILSSSILEIYNHILQTVVPDEDV---TFRKSCATKRKLSDINQEEAS- 657
Query: 401 KKGAGGIRNSNTVEFVVQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGF 460
+ + F + + + S ++T H ++ +
Sbjct: 658 ---GTSLHQKAIMTFTCHNEINAFVVLSRGSQILSLNSTRFLTKLGHCSSACPSDSVS-- 712
Query: 461 IQGLIKLKSRIEAPILCVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSK 520
Q I+ + +P+L + S V I V W+ + G + +
Sbjct: 713 -QTNIQNLKGLNSPVL-IGKSKDPSCVAKVSEEGKPAIGTQKMELHVRWRSDTGKCVDAS 770
Query: 521 -----ATYCKG--VLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFG 573
T+ K +YI S+ ++ +D + +K + D+ S+ V FI+ G
Sbjct: 771 PLVVIPTFDKSSTTVYIGSHSHRMKAVDFYSGKVKWEQILGDRIESSACVSKCGNFIVVG 830
Query: 574 TLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIW 633
+G+ L N+ W + + + + + + + + + + +W
Sbjct: 831 CYNGLVYVLKSNSGEKYWMFTTEDAVKSSATMDPTTGLIYIGSHDQHAYALDIYRKKCVW 890
Query: 634 TYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTP 693
+ G +FSS C +N +YF + +VN ++ WK P++S+P
Sbjct: 891 K-SKCGGTVFSSPC---LNLIPHHLYFATLGGLLLAVNPAT--GNVIWKHSCGKPLFSSP 944
Query: 694 TIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPII--CDDHVFIGCRNDLLY 751
+ + I DG L + + G Q+ G FSSP + +F G + +Y
Sbjct: 945 QCCS-QYICIGCVDGNL-LCFTHFGEQVWQFSTSGPIFSSPCTSPSEQKIFFGSHDCFIY 1002
>UniRef50_Q5RG49 Cluster: Novel AMP-binding enzyme domain containing
protein; n=2; Danio rerio|Rep: Novel AMP-binding enzyme
domain containing protein - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 1149
Score = 155 bits (377), Expect = 3e-36
Identities = 118/388 (30%), Positives = 184/388 (47%), Gaps = 48/388 (12%)
Query: 405 GGIRNSNT----VEFVVQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGF 460
GG+R +T + V W DTG+CVDASP L + V +GSHS ++ ++ + G
Sbjct: 776 GGVREDSTGVLPLALRVLWRSDTGRCVDASPMLLVAPDRTTVFIGSHSHRLQALDLSRGE 835
Query: 461 IQGLIKLKSRIEAPILCVHDECVTSPCG---VVGTYDGTVICFLLENC-SVIWQINVGSM 516
+ L R+E+ S CG +G YD + FL +C +W G +
Sbjct: 836 VIWERILGDRLES-------SAAISSCGGLVAIGCYDRQMY-FLDVSCGDTVWTFETGDV 887
Query: 517 IKSKATY--CKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAI-SADLVLAKNEFILFG 573
+KS T G+++ S+DG++ ++ LT T + A+ S+ V +
Sbjct: 888 VKSSPTVDPKTGLVFAGSHDGHVYALNPLTKTCTWQHYCGGGAVFSSPCVHLSPRQLYCS 947
Query: 574 TLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIW 633
+L G CL+ ++ ++W+ S P F+ P + +D V VNG I G +W
Sbjct: 948 SLGGHLHCLNPDSGKVLWKYSSSAPFFSSP--HCSDSSVFIGSVNGHI-IGISHSGNTLW 1004
Query: 634 TYNGAKGNIFSSLCVKEINKFKWQ-----------------MYFGCHDNNVYSVNITNFQ 676
++ G +FSS C+ + Q + G HD +VY +N N
Sbjct: 1005 DFS-TDGPVFSSPCISSLTLLTNQPPSTTPSSSVTTSPNHIVTCGSHDGHVYCLNAQN-- 1061
Query: 677 PSLHWKTRVSSPVYSTPTIFNDKL----ILAA--STDGKLWVIHSELGTVTAQYQLPGET 730
SL W+ + + V+STP +F+ L LAA STDGK+WV+ E G A LPGE
Sbjct: 1062 GSLLWQFQTTGKVFSTPFVFSGALWGLRTLAAVCSTDGKVWVLDGETGIQKATLSLPGEL 1121
Query: 731 FSSPIICDDHVFIGCRNDLLYSLKIDTK 758
FSSP+I + +GCRND +Y L++ T+
Sbjct: 1122 FSSPVIWGSKLVVGCRNDYVYCLELTTQ 1149
Score = 116 bits (278), Expect = 3e-24
Identities = 74/237 (31%), Positives = 124/237 (52%), Gaps = 25/237 (10%)
Query: 1 MVEILLACTNGASLLIAPD--------LTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIK 52
+VE+ LA ++GA LLI P L VLF N+ T Q TP+ + ++
Sbjct: 226 VVEVFLALSSGACLLIVPSAVKKMPRRLAHVLFKR---NTTTVLQATPTLVRRFGKVVLQ 282
Query: 53 NKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWAS---VAELD 109
++L A S+L++LA GGEP + ++K + + N+T I+ LYG TE+SCWAS V +
Sbjct: 283 EEVLSADSSLRILAFGGEPCPSLNLVKSWRQEGNRTHIYNLYGTTEVSCWASWYKVPDEH 342
Query: 110 LNKVTTGDKEVPLGNCLSETELFVQP---HEKNNTMGKIILASKTRKCILLNRKNGNKEE 166
L D VPLG + +T + V+ H G++ + + R C+L + EE
Sbjct: 343 LCLEDITDAPVPLGEPMLDTVMEVRDETGHLVTEGEGQLFIGGQNRVCLL------DDEE 396
Query: 167 NSIK--FIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
+K TGD +++N +++ GR D +KRFG +++L +++ + V +C+
Sbjct: 397 TVVKGTMRATGDWVQVQNSNLYFLGRKDRLVKRFGQRVHLDALQQMIESFSGVEACA 453
>UniRef50_UPI000155555F Cluster: PREDICTED: similar to putative
non-ribosomal peptide synthetase NRPS1098; hNRPS1098;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
putative non-ribosomal peptide synthetase NRPS1098;
hNRPS1098 - Ornithorhynchus anatinus
Length = 1121
Score = 151 bits (367), Expect = 5e-35
Identities = 113/381 (29%), Positives = 179/381 (46%), Gaps = 32/381 (8%)
Query: 391 SSHGENSISYKKGAGGIRNSNTVEFVVQWTFDTGKCVDASPALY----KSESVLYVTVGS 446
S E S + AG + V+W DTG+CVDASP + +S V VGS
Sbjct: 750 SQVSELSAPSRGPAGRRAGPGALTLRVRWRSDTGRCVDASPLVAVGTAAGDSSATVYVGS 809
Query: 447 HSGKIVVMNANTGFIQGLIKLKSRIEAPILCVHDECVTSPCG---VVGTYDGTVICFLLE 503
HSG++ ++ +G ++ L R+E+ C+ S CG VG YDG V
Sbjct: 810 HSGRLQALDLRSGRLKWERVLGDRVES------SACL-SRCGRLVAVGCYDGFVYVLRSA 862
Query: 504 NCSVIWQINVGSMIKSKATY--CKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISAD 561
W+ +KS A G+LY+ S+D ++ +D+ +H A+ A
Sbjct: 863 TGETHWRFATRDAVKSSAALDPSTGLLYVGSHDQHVYALDVYERKRVWELHCGGGAVFAS 922
Query: 562 LVLAKNEFILF-GTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGE 620
L+ L+ TL G+ ++ + +W+ S P+F+ P V V+G
Sbjct: 923 PCLSLAPHRLYVATLGGLLVAVNPASGHGVWKHSCGKPLFSSPRCCPPG--VCVGCVDGN 980
Query: 621 IHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLH 680
++C G ++W + G +FSS C+ + ++ G HD VY + Q
Sbjct: 981 LYCFN-HAGEQVWQLSTG-GPVFSSPCIWAADDRN--LFLGSHDGCVYCCDAEGRQ---R 1033
Query: 681 WKTRVSSPVYSTPTIFN------DKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSP 734
WK S+PVY+TP F + L+ AASTDG+LWV+ +E G A +LPG+ FSSP
Sbjct: 1034 WKFAASAPVYATPFAFRSPRPAGETLVAAASTDGRLWVLDAESGQARATAELPGQVFSSP 1093
Query: 735 IICDDHVFIGCRNDLLYSLKI 755
++ + +GCR+D +Y L++
Sbjct: 1094 VVWGALLVVGCRDDGVYGLEL 1114
Score = 136 bits (330), Expect = 2e-30
Identities = 89/299 (29%), Positives = 149/299 (49%), Gaps = 21/299 (7%)
Query: 1 MVEILLACTNGASLLIAPD--------LTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIK 52
+V++ +A T+GASLL+ PD L LFH + VT Q TP+ + +K
Sbjct: 302 VVDLFVALTSGASLLMVPDAVKMVPSQLAAALFHR---HGVTVLQATPTLLRRFGARLLK 358
Query: 53 NKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWAS---VAELD 109
+ L A S L+VLALGGEP + + + + N T++F +YGVTE+S WA+ + D
Sbjct: 359 STALSAGSPLRVLALGGEPFPALATFRSWRAEGNGTQVFNVYGVTEVSSWATCYRIPAAD 418
Query: 110 LNKVTTGDKEVPLGNCLSETELFVQPHEK---NNTMGKIILASKTRKCILLNRKNGNKEE 166
L+ ++ + VPLG L T + V+ + + G++ + + R C L +
Sbjct: 419 LDPSSSSESPVPLGAPLLGTIVEVRDPDGCRIEDGDGQVFIGGEERVCFL----DDETTV 474
Query: 167 NSIKFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
S TGD+ ++ +F+ GR D IKR G ++NL ++ + +C+ W
Sbjct: 475 PSGTMRATGDLVTVKGEDLFFLGRKDGQIKRHGKRLNLEGVQQAAERLCGAEACAVTWAP 534
Query: 227 TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
LL+ + L+ ++LL L+ +L PD ++ V+ LP +HGK + L +Y
Sbjct: 535 REGLLLFVVPSGRLAKEQLLGELERRLPRHALPDDLVFVEALPFTSHGKIDRPALTKMY 593
>UniRef50_A7RVL7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1049
Score = 139 bits (337), Expect = 2e-31
Identities = 113/398 (28%), Positives = 183/398 (45%), Gaps = 48/398 (12%)
Query: 392 SHGENSISYKKGAGGIRNSNTVEFVVQWTFDTGKCVDASP-------------------- 431
SH + +SY +G + TV+ +W + KC DASP
Sbjct: 667 SHSD-CVSY---SGRRLGNRTVQLSKKWRANLYKCTDASPLVVGCRVADLDSTEKGSGEA 722
Query: 432 ALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCVHDECVTSPCGVVG 491
AL+ ES L V VGSH+ M + G + ++ RIE+ V C T C + G
Sbjct: 723 ALFHVESGL-VYVGSHAHVFKAMRLSDGEVMWETEVGDRIESS--AVLSRCGT--CIIFG 777
Query: 492 TYDGTVICFLLENCSVIWQINVGSMIKSKATY--CKGVLYIASYDGNIRCIDILTSTIKE 549
YDG + + + W + +KS G++++ S+D ++ +DI
Sbjct: 778 CYDGKIYIINRFSGVIGWTYQTHAPVKSSPCVDPTTGLVWVGSHDHHLYALDITNRVSAC 837
Query: 550 TVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDND 609
+ S+ + E + TLSGV C++ + I W P+FA P++ D
Sbjct: 838 AIDCGGSCFSSPRLNPTWERLFAATLSGVLLCINTSDMMIDWSTKCPKPVFASPLV--TD 895
Query: 610 KYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSS-LCVKEINKFKWQMYFGCHDNNVY 668
V+ V+G ++ + G +W+ G IFSS + + + + + FGCHD++VY
Sbjct: 896 VGVVCGCVDGYLYAFDLS-GAPLWSL-ATSGPIFSSPVLARRRSLCQEAIVFGCHDSHVY 953
Query: 669 SVNITNFQPSLHWKTRVSSPVYSTPTI---------FNDKLILAASTDGKLWVIHSELGT 719
V+ L W + SP+YSTP I D+L+L AST G ++++ + G
Sbjct: 954 CVSTRG---ELEWSFKADSPIYSTPFINFISTKRDTLEDELVLVASTRGTVYMLTLDTGC 1010
Query: 720 VTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKIDT 757
+ LPGE FSSP+I + IGCR++ LYSLK+++
Sbjct: 1011 LLGSMALPGEVFSSPVIGRGAILIGCRDNYLYSLKVES 1048
Score = 99 bits (238), Expect = 2e-19
Identities = 108/428 (25%), Positives = 192/428 (44%), Gaps = 38/428 (8%)
Query: 1 MVEILLACTNGASLLIAPDLTEVLFHE----DNDNSVTFWQTTPSKFFQHSNENIKNKIL 56
+V++ LA GA ++ + +L ++T Q TPS + I+ +L
Sbjct: 189 VVQVFLALEAGARAVLLHETDRILPSRLCSVIKSQNITILQPTPSLMNYIGLDLIRTSLL 248
Query: 57 CARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDL-----N 111
S L+VLALGGEP +L + KH + T+IF LYG+TE+S WA+ ++ +
Sbjct: 249 AHDSPLRVLALGGEPFPSTSVLFQWKHPDCTTKIFNLYGITEVSSWATCQKIVICSKGAQ 308
Query: 112 KVT------TGDKEVPLGNCLSETELFVQPHEK---NNTMGKIILASKTRKCILLNRKNG 162
+V+ + D+ +P+G L +T + ++ E ++ +G++ + + R C L N
Sbjct: 309 QVSKDGVHLSVDERIPIGEPLQDTLVDIRDEEGKKISHGIGQMYIGGQNRICFL----NN 364
Query: 163 NKEENSIKFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
+ + +GD I N +++ GR D IKR G + NL IE + + +
Sbjct: 365 EMDVSPGTMRASGDWALINNDQIWFLGRKDRQIKRLGQRTNLLWIEQALARVLPRHTFVA 424
Query: 223 VWLQTPL--LLIVYFSAETLSSQEL----LDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
V +++ + L + S++ SS +L +K L PD + V LP +HGK
Sbjct: 425 VVVKSKMDRLHLFVTSSDDSSSWDLSFRVRSIIKDVLPVHAHPDHIHIVSDLPLTSHGKV 484
Query: 277 SKEILVNIYKKSNILQNVE-NIKSYLFKELKALVNKDLNYEDLQSKS-FFSLGGTSFLAV 334
E L+ + Q+VE + + ++ K +++ S F + GG S AV
Sbjct: 485 DMETLLEGIRS---YQHVETSSRGHINKMWLEATGSSSRLTLVEAGSMFLASGGNSLQAV 541
Query: 335 TICNKLS--LTFPEVGKHI-LPHLLS--HNKSIGDVLKTITQDTNCLENKFKKSIKRNRS 389
+ ++ L + GK + L LL NK G++ + + Q + L ++ K
Sbjct: 542 KLAESITWWLQKNKSGKCLELDDLLDVILNKPFGELCRYVEQKCSVLHTDDERLDKGAHV 601
Query: 390 TSSHGENS 397
S NS
Sbjct: 602 ISEWNGNS 609
>UniRef50_UPI0000DB6DE1 Cluster: PREDICTED: similar to 2-aminoadipic
6-semialdehyde dehydrogenase; n=1; Apis mellifera|Rep:
PREDICTED: similar to 2-aminoadipic 6-semialdehyde
dehydrogenase - Apis mellifera
Length = 653
Score = 126 bits (304), Expect = 2e-27
Identities = 79/234 (33%), Positives = 131/234 (55%), Gaps = 15/234 (6%)
Query: 1 MVEILLACTNGASL-LIAPDLT---EVLFHEDNDNSVTFWQTTPSKF-FQHSNENIKNKI 55
++EI LA +N +L +++ L + L + +T Q TPS F + S E++K+ I
Sbjct: 76 IIEIFLALSNAGTLFMVSKSLKNNPDRLLKIAYSSQITILQITPSVFIYNWSPESLKSSI 135
Query: 56 LCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTT 115
L ++L+ + GGEP ++++ E H N T+I+ +YG+TE+SCWAS+ E+ +T
Sbjct: 136 LSNNTSLRAILFGGEPFPKLEVISETMHPYNNTKIYNIYGITEVSCWASINEI---LITG 192
Query: 116 GDKEVP-LGNCLSETELFVQPHEK---NNTMGKIILASKTRKCILLNRKNGNKEENSIKF 171
G V LG LS T L V+ N G + + S R C L+N +N E + F
Sbjct: 193 GQFNVHYLGQVLSHTLLQVRNKRGEVITNGTGFLYIGSNQRVC-LVNDENIEDLELPV-F 250
Query: 172 IDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW 224
D+GDI +I G +FY+GR + IKRFG+K++L ++ ++Q +++C +W
Sbjct: 251 RDSGDIVDINEEGKIFYKGRKNSFIKRFGNKVDLTKLKEFILQIDFIKNCYVLW 304
Score = 78.2 bits (184), Expect = 8e-13
Identities = 50/156 (32%), Positives = 79/156 (50%), Gaps = 14/156 (8%)
Query: 525 KGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLA-KNEFILFGTLSGVCACLH 583
KG++++ SYD I C+ + + + +I+A L +++ +LFGTL G C L
Sbjct: 503 KGIIFVGSYDCYIYCLSVKDGSEIWKFKFGNGSINASGCLHFQSDTVLFGTLDGYCLALQ 562
Query: 584 VNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTY--NGAK-- 639
+ ++W+ L PIF PV +N V+F V G + C +E +K+WTY N K
Sbjct: 563 QLSGKLVWKYKLSDPIFVAPVSLNNG-LVLFCSVTGLLCCFDIEVNVKMWTYKINVIKIE 621
Query: 640 ---GNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNI 672
+FSS V N + GC DNNVY++ +
Sbjct: 622 KLPAEVFSSPVVN--NNV---IIIGCRDNNVYALEL 652
Score = 71.7 bits (168), Expect = 7e-11
Identities = 52/193 (26%), Positives = 91/193 (47%), Gaps = 13/193 (6%)
Query: 411 NTVEFVVQWTFDTGKCVDASPALYK-SESVLYVTVGSHSGKIVVMNANTGFIQGL--IKL 467
N ++ +Q T+D KCVDASP +++ S+ Y TVGSHSG I + + +KL
Sbjct: 420 NYIKIKIQKTYDMRKCVDASPTIFRYSDGKTYATVGSHSGFIFTFELEKECHKRIFKVKL 479
Query: 468 KSRIEAPILCVHDECVTSPC----GV--VGTYDGTVICFLLENCSVIWQINVGS-MIKSK 520
RIE+ +L + + C G+ VG+YD + C +++ S IW+ G+ I +
Sbjct: 480 PDRIESSVLILDNFRGIVGCYDEKGIIFVGSYDCYIYCLSVKDGSEIWKFKFGNGSINAS 539
Query: 521 AT--YCKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGV 578
+ + + DG + L+ + +SD A + L N +LF +++G+
Sbjct: 540 GCLHFQSDTVLFGTLDGYCLALQQLSGKLVWKYKLSDPIFVAPVSL-NNGLVLFCSVTGL 598
Query: 579 CACLHVNTKTIIW 591
C + +W
Sbjct: 599 LCCFDIEVNVKMW 611
Score = 70.1 bits (164), Expect = 2e-10
Identities = 43/158 (27%), Positives = 76/158 (48%), Gaps = 13/158 (8%)
Query: 606 YDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDN 665
YD + + I+C +V+ G +IW + G+I +S C+ + + FG D
Sbjct: 500 YDEKGIIFVGSYDCYIYCLSVKDGSEIWKFKFGNGSINASGCLHFQSD---TVLFGTLDG 556
Query: 666 NVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQ 725
Y + + L WK ++S P++ P N+ L+L S G L E+ Y+
Sbjct: 557 --YCLALQQLSGKLVWKYKLSDPIFVAPVSLNNGLVLFCSVTGLLCCFDIEVNVKMWTYK 614
Query: 726 --------LPGETFSSPIICDDHVFIGCRNDLLYSLKI 755
LP E FSSP++ ++ + IGCR++ +Y+L++
Sbjct: 615 INVIKIEKLPAEVFSSPVVNNNVIIIGCRDNNVYALEL 652
>UniRef50_Q8I104 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 714
Score = 105 bits (253), Expect = 3e-21
Identities = 165/600 (27%), Positives = 258/600 (43%), Gaps = 80/600 (13%)
Query: 1 MVEILLACTNGASLLIAPDLTEVLFHEDNDN----SVTFWQTTPSKFFQHSNENIKNKIL 56
+VE+ +A G +L+I PD H+ + T Q TP+ F + + +L
Sbjct: 171 IVELFMAFHVGCTLIITPDEYRSEPHKLQKSIDKFQPTVVQLTPTVFEMLPSAD---SLL 227
Query: 57 CARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
A S+L++L LGG I + + NKTR+F +YGVTE+SCWAS E V G
Sbjct: 228 SATSSLRILLLGGSHFP-ISSINSCRSPENKTRVFNVYGVTEVSCWASYFE-----VEHG 281
Query: 117 DKEVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSIKFIDTGD 176
EV +G + T+L V ++ G++IL R+C + +G K N TGD
Sbjct: 282 CSEVLIGEAIYGTQLGV------DSDGQLILGG-PRQCYV----DGVKALNH----KTGD 326
Query: 177 IGEI-RNGTVFYRGRVDDTIKRFGHKINL-HSIESTVMQCPRVRSCSCVWLQTPLLLIVY 234
E+ NG GR+D IK G +I L H + P ++S + L IV
Sbjct: 327 RVEVTENGGQKIVGRIDRLIKHRGIRICLDHLSHVALRHDPSIQSLHTMLLDN--RNIVQ 384
Query: 235 FSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNV 294
F SS L+ P VI+V LP N+ GK ++ L IY K + N
Sbjct: 385 FHVGPGSSSPTHKTLRLDATTVV-PITVIQVAELPINSSGKVDEKALERIYGKVSGGGN- 442
Query: 295 ENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTFPEVGK--HIL 352
+ ++LK +++ L+ SF SLG S LA + TF +V + ++
Sbjct: 443 SKFQEIFEQKLKVKLSEVLDV------SFVSLGVNSLLAAELS-----TFFQVSQQTEVM 491
Query: 353 PHLLSHNKSIGDVLKTITQDTNCLENKFKKSIKRNRSTSSHGENSISYKKGAGGIRNSNT 412
+L+ +GDVL+ KF+ S K SH + + +K IR
Sbjct: 492 RRMLNETVPVGDVLR-----------KFELSPK----LQSHVDFEV--RK---IIRKRQP 531
Query: 413 VEFVVQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIE 472
++W D KC+D + + + V SH+G ++ +N TG + + R E
Sbjct: 532 ---KMRWAVDLRKCIDGNLLVICN---TLVVCASHAGIVIAVNPQTGNLIWRAECGVRFE 585
Query: 473 APILCVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIAS 532
+ V+D+ V C G Y V ++N SVI + VG ++++ + G +Y +
Sbjct: 586 CKPILVNDQVVLG-CKSTGLYFICVKTGQIQN-SVILE-TVG--VRAQCAFDGGAIYCTT 640
Query: 533 YDGNIRCIDILT--STIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTII 590
+GN ID T S + S V+A + I +G V K+II
Sbjct: 641 ENGNFHVIDPKTYGSIYSHAISKIPGGTSVGPVIAPDGSIFATITAGAVLRTTVPRKSII 700
Score = 34.7 bits (76), Expect = 9.4
Identities = 17/82 (20%), Positives = 38/82 (46%)
Query: 676 QPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPI 735
QP + W + + + + L++ AS G + ++ + G + + + PI
Sbjct: 530 QPKMRWAVDLRKCIDGNLLVICNTLVVCASHAGIVIAVNPQTGNLIWRAECGVRFECKPI 589
Query: 736 ICDDHVFIGCRNDLLYSLKIDT 757
+ +D V +GC++ LY + + T
Sbjct: 590 LVNDQVVLGCKSTGLYFICVKT 611
>UniRef50_Q0DF72 Cluster: Os06g0111600 protein; n=4; Oryza sativa|Rep:
Os06g0111600 protein - Oryza sativa subsp. japonica
(Rice)
Length = 1054
Score = 101 bits (243), Expect = 5e-20
Identities = 90/370 (24%), Positives = 155/370 (41%), Gaps = 43/370 (11%)
Query: 419 WTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCV 478
W G CVDASP L + +L + +GSHS + + ++ +G ++ +KL+ R+E
Sbjct: 697 WNIPLGSCVDASPLLVSNNGMLSIFIGSHSHRFLCIDGCSGSVRWSVKLEGRVECSAAIT 756
Query: 479 HDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSK--ATYCKGVLYIASYDGN 536
D VVG Y G + L W I +K + + +++ SYD +
Sbjct: 757 GDFSEV----VVGCYKGKIYFLDLLTGKQAWTIQTDGEVKMQPAVDMIRNLIWCGSYDHH 812
Query: 537 IRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCAC--LHVNTKTIIWQGS 594
+ ++ + + + + I + SG+ L V++ IIWQ
Sbjct: 813 LYALNYKDRCCTYKISCGGSIYGSPAIDMTHNMIYVASTSGLVTAISLEVSSFKIIWQYE 872
Query: 595 LKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKF 654
PIF ++ + VI VNG + G +W + G IF+ C+ +
Sbjct: 873 AGAPIFGSLAIHHHGGKVICCLVNGLVIALN-SHGSVVWKAS-VGGPIFAGACLS--SGL 928
Query: 655 KWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAAS--------- 705
Q+ D +YS + T+ +L WK V P+ T + F D+++ A S
Sbjct: 929 PTQVLIPSRDGRLYSFDTTS--GALLWKYEVGDPI--TASAFVDEVLTATSPGASERFAC 984
Query: 706 ---TDGKLWVIH---------------SELGTVTAQYQLPGETFSSPIICDDHVFIGCRN 747
+ G++ VI ++L A LPG+ FSSP++ +F+GCR+
Sbjct: 985 ICTSSGQVHVIRIRADAKEEKVNGSICNDLVQGFAAIDLPGDIFSSPLMVGGRIFVGCRD 1044
Query: 748 DLLYSLKIDT 757
D L+ L I +
Sbjct: 1045 DQLHCLTISS 1054
Score = 53.6 bits (123), Expect = 2e-05
Identities = 74/325 (22%), Positives = 133/325 (40%), Gaps = 36/325 (11%)
Query: 50 NIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMS-------CW 102
+++ + + LK+L GE L+ I + K + +T I LYG TE+S C
Sbjct: 208 SLEKNLSWGHNPLKMLIFSGENLS-ILLWKRVHEILPETTIVNLYGTTEVSGDCTFFDCT 266
Query: 103 ASVAELDLNKVTTGDKEVPLGNC--LSETELFVQPHEKNNTMGKIILASKTRKCILLNRK 160
L ++T+ P+ NC T+ V + + G + A + + N
Sbjct: 267 DLPILLKREELTSVPIGFPISNCEVCIATDAEVADEGEMHVTGACLFAGYLEESMASNHT 326
Query: 161 NGNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRS 219
N S + TGD +++G + GR D T+K +G + +L +EST+ + P V +
Sbjct: 327 EDN---GSSTYYRTGDFARRLKSGEFIFLGRKDRTVKIYGQRFSLQEVESTLNEHPDVSA 383
Query: 220 CSCVWLQTPLL-----LIVYFSAETL---------SSQELL-----DFLKCKLDEKYWPD 260
+ + L L++ SA ++ S E++ +L KL P
Sbjct: 384 AAVTFQNNEFLDFRAYLVLKSSAASVEDCQRRKRYKSFEVIMPSIRSWLIMKLPPAMIPR 443
Query: 261 KVIRVDTLPTNAHGKTSKEILVNI---YKKSNILQNVENIKSYLFKELKALVNKDLNYED 317
+ +++LP + GK L ++ + + +L KA + L E
Sbjct: 444 FFLPMESLPLTSSGKIDYMKLSSLKCALESCETETERITVNPHLQVIKKAFSDALLVDEV 503
Query: 318 LQSKSFFSLGGTSFLAVTICNKLSL 342
+ FF+LGG S A + +KL +
Sbjct: 504 SEFDDFFTLGGNSISAAHVAHKLEI 528
>UniRef50_A0UXD2 Cluster: Amino acid adenylation domain; n=1;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 4196
Score = 96.7 bits (230), Expect = 2e-18
Identities = 106/463 (22%), Positives = 206/463 (44%), Gaps = 41/463 (8%)
Query: 32 SVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIF 91
++ Q TPS NE +KN + C S +V+ +GGE +L+EL+ K K +I+
Sbjct: 3650 NIDMLQMTPSTLQILMNE-LKN-LSCFNSVKQVM-IGGEAFPET-LLRELR-KVYKGKIY 3704
Query: 92 TLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKNNTM---GKIILA 148
+YG TE + W+++ +L N V +G ++ T++ + + + G++ +
Sbjct: 3705 NMYGPTETTVWSAIKDLTKNSC------VSIGGPIANTQILIMNGDNLQPIGVAGEVCIG 3758
Query: 149 SKTRKCILLNRKNGNKEE-------NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGH 200
+ LNR KE+ + TGD+ + + +G++ + GR+D+ +K G+
Sbjct: 3759 GDSLARGYLNRSELTKEKFVSSELVPGKRLYKTGDLAKWMPDGSIAFMGRIDNQVKIRGY 3818
Query: 201 KINLHSIESTVMQCPRVRSCSCVWLQTPL----LLIVYFSAETLSSQELLDFLKCKLDEK 256
+I L IE +++ + C + + L+ Y S+E ++ E++ + L +
Sbjct: 3819 RIELDEIEKCILKYNLINECVVIAQEDEFSNKQLICYYVSSEEITVSEIMQHIGRDLPDY 3878
Query: 257 YWPDKVIRVDTLPTNAHGKTSKEILVNI-YKKSNILQNVENIKSYLFKELKALVNKDLNY 315
P +R+ ++P +GK + L + NI + S + K++ + L
Sbjct: 3879 MIPGIYVRLASIPLTPNGKVDRRALPAAGTARPNIDSEYKEANSEIEKKIAEIWKSILKC 3938
Query: 316 EDLQ-SKSFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQDTN 374
+ + + SFF LGG S L V + +L +P GK + L HN +I + + I+QD
Sbjct: 3939 DQIGINDSFFQLGGNSILLVRMHEELEKHYP--GKINVSKLFIHN-TIAKLSEFISQDDK 3995
Query: 375 CLENKFKKSIKRNRSTSSHGENSISYKKGAGGIR-NSNTVEFVVQWTFDTGKCV-DASPA 432
NK + R G Y+ A S+ + ++ D+G+ + + A
Sbjct: 3996 KAVNKLELEATRLPQDYFTGSMHEQYENKAFKYSFTSDLSNKITNFSLDSGQGLKEILLA 4055
Query: 433 LY--------KSESVLYVTVGSHSGKIVVMNANTGFIQGLIKL 467
LY + E ++ T+ + +I+ + N G + L L
Sbjct: 4056 LYFYLLYQVSEEERIVVHTITDNENRILPLGMNIGEVDELDSL 4098
Score = 91.5 bits (217), Expect = 8e-17
Identities = 86/355 (24%), Positives = 159/355 (44%), Gaps = 21/355 (5%)
Query: 9 TNGASLLIAPDLT--EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLA 66
T G + +P L E + N VT TPS F+ + N + L +S +V
Sbjct: 1511 TGGCLCIFSPGLYDYERMSEVINKEHVTMINCTPSAFYPLIDFNADSGFLRLQSLSRVF- 1569
Query: 67 LGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCL 126
LGGEP+N K+L K I YG TE + AS +D N + + VP+G +
Sbjct: 1570 LGGEPINMGKLLPWRKSMAYSADIVNTYGPTECTDIASFYRID-NNIIEQETAVPIGKPI 1628
Query: 127 SETELFV----QPHEKNNTMGKIILASKTRKCILLNRKNGNKEE-------NSIKFIDTG 175
++++ Q +G++ + N KE + K TG
Sbjct: 1629 DNVQIYILDKNQKLVPQGMVGELCIGGIGLTRGYYNDPGLTKERFIECEGISGRKVYRTG 1688
Query: 176 DIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL---LL 231
D+ + + G + + GRVD+ +K G++I + IE++++ P +R + + +
Sbjct: 1689 DLAKWTQEGNIEFLGRVDNQVKIRGYRIEMGEIEASILSHPAIREAVAIAKEDSTGGKYI 1748
Query: 232 IVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNI 290
Y ++T LS EL D+L+ L P + ++++ +P +GK +++ L + S
Sbjct: 1749 CAYIVSDTGLSITELRDYLQKSLPGYMIPSRFVQIEKMPLTPNGKINRKALPEPDRISLT 1808
Query: 291 LQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLSLTF 344
+ ++ L + L + + LN + L +++FF LGG S A+ + +++ F
Sbjct: 1809 ETERQKPQNELEERLADIFKEILNTDILGVTENFFDLGGNSLSAMILSLRINKEF 1863
Score = 66.5 bits (155), Expect = 3e-09
Identities = 77/346 (22%), Positives = 149/346 (43%), Gaps = 26/346 (7%)
Query: 62 LKVLALGGEPLNGIKILKEL-KHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
+K +GGE L+ + K + + N I +YG TE ++ L+ + + G K +
Sbjct: 521 VKHFIIGGEALHYTTVEKFYSRFEGNTPEITNVYGPTECCVDSTFYTLNPSDLA-GSKII 579
Query: 121 PLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE---NSI---- 169
P+G + ++++ + +G++ ++ L+R+ E N
Sbjct: 580 PIGKPMPNVQVYILGENQELIPRGCIGEVYISGTGVGVGYLSREQMTSERFIPNPFNVDK 639
Query: 170 KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP 228
K TGD+G + +G + + GR D +K G++I L IE+ + + +R +
Sbjct: 640 KMYKTGDLGRWLPDGNIEFIGRKDGQVKIRGYRIELGEIEAQLQKHENIREAVVTDRKED 699
Query: 229 L---LLIVYFSA-ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
+L YF+A E L +L + L K+ E P ++++ +P +GK K L N
Sbjct: 700 SENKVLCAYFTANEKLGVTQLREHLSDKIPEYMIPTYFVQIEKMPLTINGKLDKNALPN- 758
Query: 285 YKKSNILQNVENI--KSYLFKELKALVNKDLNYEDLQSKS-FFSLGGTSFLAVTICNKLS 341
K + + E I ++ + L + E L K F+ LGG S A+T+ +++
Sbjct: 759 -PKDTLKKRTEYIEPRNNTEQSLVPIWQDVFQIEKLGIKDDFYELGGHSLKAITLSSRI- 816
Query: 342 LTFPEVGKHILPHLLSHNKSIGDVLKTITQDTNCLENKFKKSIKRN 387
F ++ + +L +I + K I + L K +R+
Sbjct: 817 --FKDLNVEVPISILLSTPNIEGIAKYIDSKSKALYINLKPVEERD 860
Score = 56.8 bits (131), Expect = 2e-06
Identities = 86/373 (23%), Positives = 161/373 (43%), Gaps = 42/373 (11%)
Query: 2 VEILLACTNGASL----LIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC 57
++I A NGA + L E + + +NS++ T PS + K K +
Sbjct: 2565 IDIFSALLNGAGIYPYDLKNKGSIENMSNWIEENSISILHTVPSIYRYFIKSIDKTKRI- 2623
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFT-LYGVTEMSCWASVAELDLNKVTTG 116
S +++ LGGE + I +E K + IF L+G +E+ A+ +D N
Sbjct: 2624 --SDTRLIILGGEVVYSSDI-EEYKLLFSDDCIFVNLFGASEILV-ATFYLVDKN-TQVN 2678
Query: 117 DKEVPLGNCLSETELFVQPHEKNNT----MGKIILASK--TRKCILLNRKNG-----NKE 165
+ VP+G L + + + G+++ S ++ L+ K N E
Sbjct: 2679 TRTVPIGYELEGVSIQLLNDDNKAAGIYECGELVYHSHYLSQGYWNLDEKTNHQFERNPE 2738
Query: 166 ENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW 224
+ +GD+ + +GT+ + GR D +K G +I L IES V +R C+ +
Sbjct: 2739 TGEVIAYKSGDLARLLPSGTIEHLGRKDTQVKIRGMRIELTEIESVVGGLKGIRECAAIV 2798
Query: 225 LQTP---LLLIVYF---SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
L+ P ++V++ + E + +++ LK KL E P + V+++P +GK +
Sbjct: 2799 LEKPNQENTIVVFYVPENEEVIENKQFKLMLKSKLPEYMIPSLLYPVESIPHTPNGKVDR 2858
Query: 279 EIL--VNIYKKSNI-----LQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSF 331
+ L N+ K VE + ++ E+ + +N ++FF LGG S
Sbjct: 2859 KALSIKNVDVKEEAAYEPPTNQVEERMTEIWSEILEIGKIGVN------ENFFELGGHSL 2912
Query: 332 LAVTICNKLSLTF 344
A ++ +++ F
Sbjct: 2913 KATSLVSRIHKAF 2925
>UniRef50_Q0V991 Cluster: U26 protein; n=11; Tetrapoda|Rep: U26
protein - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 415
Score = 89.4 bits (212), Expect = 3e-16
Identities = 51/145 (35%), Positives = 87/145 (60%), Gaps = 14/145 (9%)
Query: 1 MVEILLACTNGASLLIAPD--------LTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIK 52
++E+ LA ++GA LL+ P+ L ++LFH+ + VT Q TP+ + + +I+
Sbjct: 261 VIELFLALSSGACLLVVPNPIKMMPHKLCDILFHQ---HRVTVLQATPTFLRRFGSRSIR 317
Query: 53 NKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNK 112
+ +L ++L+VLALGGEP + +L+ + N+TR+ LYG+TE+S WA+ E+
Sbjct: 318 SSVLSKGTSLRVLALGGEPFPSVSVLRSWREPGNRTRLINLYGITEVSSWATYYEITEQM 377
Query: 113 VT--TGDKE-VPLGNCLSETELFVQ 134
++ TG++ VPLG L T + VQ
Sbjct: 378 ISHQTGEESCVPLGFPLQGTIVEVQ 402
>UniRef50_O27529 Cluster: Serine/threonine protein kinase related
protein; n=1; Methanothermobacter thermautotrophicus
str. Delta H|Rep: Serine/threonine protein kinase
related protein - Methanobacterium thermoautotrophicum
Length = 407
Score = 88.6 bits (210), Expect = 5e-16
Identities = 80/341 (23%), Positives = 143/341 (41%), Gaps = 29/341 (8%)
Query: 419 WTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCV 478
W G + +SPA++ V Y+ GS G++ +N TG + K + I V
Sbjct: 53 WYLSIGG-IKSSPAIFNK--VAYI--GSLDGRLYAVNLETGSVVWSYKTEGAI------V 101
Query: 479 HDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNIR 538
V + VG++DG + + + W+ G+ I+S +YI S D +
Sbjct: 102 SSPVVVNGTVFVGSWDGYLYAIDTDTGDLEWKFKTGNRIESSPAVSGDTVYIGSDDCRVY 161
Query: 539 CIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGP 598
+D + K + D S+ L + N + G+ +G L + +W +
Sbjct: 162 AVDRDDGSKKWEFYTGDAVKSSPLPV--NGTLYVGSFNGKVYALSESDGNEVWSYTSGDA 219
Query: 599 IFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQM 658
I + P ++ YV +G I+ + G IW Y+ ++SS ++ + +
Sbjct: 220 IRSSPAFWNGTVYV--GSDDGNIYALSESDGNVIWKYS-LGDRVYSS---PSVDTEENSV 273
Query: 659 YFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELG 718
+ GC D N+ S++ +L W +PV STP +F + +I S DG L++++ G
Sbjct: 274 FIGCDDGNITSLDTRT--GALKWSFHTGAPVRSTPALF-ENMIAVGSDDGTLYILNKYSG 330
Query: 719 TVTAQYQLPG------ETFSSPIICDDHVFIGCRNDLLYSL 753
Y PG SSP++ V+ N +Y+L
Sbjct: 331 REEWSYS-PGYYLFSSPVSSSPVVYGKTVYFATENGYIYAL 370
Score = 66.1 bits (154), Expect = 3e-09
Identities = 51/255 (20%), Positives = 106/255 (41%), Gaps = 13/255 (5%)
Query: 417 VQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPIL 476
++W F TG +++SPA+ S +Y+ GS ++ ++ + G + +++ L
Sbjct: 130 LEWKFKTGNRIESSPAV--SGDTVYI--GSDDCRVYAVDRDDGSKKWEFYTGDAVKSSPL 185
Query: 477 CVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGN 536
V+ VG+++G V + + +W G I+S + G +Y+ S DGN
Sbjct: 186 PVNGTLY------VGSFNGKVYALSESDGNEVWSYTSGDAIRSSPAFWNGTVYVGSDDGN 239
Query: 537 IRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLK 596
I + + + D+ S+ V + + G G L T + W
Sbjct: 240 IYALSESDGNVIWKYSLGDRVYSSPSVDTEENSVFIGCDDGNITSLDTRTGALKWSFHTG 299
Query: 597 GPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKW 656
P+ + P L++N + +G ++ G + W+Y+ +FSS +
Sbjct: 300 APVRSTPALFEN--MIAVGSDDGTLYILNKYSGREEWSYSPGY-YLFSSPVSSSPVVYGK 356
Query: 657 QMYFGCHDNNVYSVN 671
+YF + +Y+++
Sbjct: 357 TVYFATENGYIYALD 371
Score = 62.5 bits (145), Expect = 4e-08
Identities = 54/251 (21%), Positives = 106/251 (42%), Gaps = 16/251 (6%)
Query: 509 WQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKNE 568
W +++G + S A + K V YI S DG + +++ T ++ + +S+ +V+ N
Sbjct: 53 WYLSIGGIKSSPAIFNK-VAYIGSLDGRLYAVNLETGSVVWSYKTEGAIVSSPVVV--NG 109
Query: 569 FILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEK 628
+ G+ G + +T + W+ I + P + + Y+ + ++ +
Sbjct: 110 TVFVGSWDGYLYAIDTDTGDLEWKFKTGNRIESSPAVSGDTVYI--GSDDCRVYAVDRDD 167
Query: 629 GIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSP 688
G K W + S L V +Y G + VY+++ ++ W
Sbjct: 168 GSKKWEFYTGDAVKSSPLPV------NGTLYVGSFNGKVYALSESDGNEV--WSYTSGDA 219
Query: 689 VYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIIC--DDHVFIGCR 746
+ S+P +N + S DG ++ + G V +Y L +SSP + ++ VFIGC
Sbjct: 220 IRSSPAFWNG-TVYVGSDDGNIYALSESDGNVIWKYSLGDRVYSSPSVDTEENSVFIGCD 278
Query: 747 NDLLYSLKIDT 757
+ + SL T
Sbjct: 279 DGNITSLDTRT 289
Score = 59.7 bits (138), Expect = 3e-07
Identities = 65/304 (21%), Positives = 125/304 (41%), Gaps = 24/304 (7%)
Query: 417 VQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPIL 476
V W++ T + +SP + V VGS G + ++ +TG ++ K +RIE+
Sbjct: 90 VVWSYKTEGAIVSSPVVVNGT----VFVGSWDGYLYAIDTDTGDLEWKFKTGNRIES--- 142
Query: 477 CVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGN 536
V+ +G+ D V ++ S W+ G +KS G LY+ S++G
Sbjct: 143 ---SPAVSGDTVYIGSDDCRVYAVDRDDGSKKWEFYTGDAVKSSPLPVNGTLYVGSFNGK 199
Query: 537 IRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLK 596
+ + + + S AI + N + G+ G L + +IW+ SL
Sbjct: 200 VYALSESDGN-EVWSYTSGDAIRSSPAF-WNGTVYVGSDDGNIYALSESDGNVIWKYSLG 257
Query: 597 GPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYN-GAKGNIFSSLCVKEINKFK 655
+++ P + + V +G I G W+++ GA +L F+
Sbjct: 258 DRVYSSPSVDTEENSVFIGCDDGNITSLDTRTGALKWSFHTGAPVRSTPAL-------FE 310
Query: 656 WQMYFGCHDNNVYSVNITNFQPSLHWKT---RVSSPVYSTPTIFNDKLILAASTDGKLWV 712
+ G D +Y +N + + + SSPV S+P ++ K + A+ +G ++
Sbjct: 311 NMIAVGSDDGTLYILNKYSGREEWSYSPGYYLFSSPVSSSPVVYG-KTVYFATENGYIYA 369
Query: 713 IHSE 716
+ S+
Sbjct: 370 LDSK 373
Score = 58.8 bits (136), Expect = 5e-07
Identities = 31/116 (26%), Positives = 58/116 (50%), Gaps = 3/116 (2%)
Query: 642 IFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLI 701
I + + ++ W ++ G + Y+ ++F W + + S+P IFN K+
Sbjct: 15 IILGMILSPVSAADWPVFHGDEQHTGYAKEPSDFSAKT-WYLSIGG-IKSSPAIFN-KVA 71
Query: 702 LAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKIDT 757
S DG+L+ ++ E G+V Y+ G SSP++ + VF+G + LY++ DT
Sbjct: 72 YIGSLDGRLYAVNLETGSVVWSYKTEGAIVSSPVVVNGTVFVGSWDGYLYAIDTDT 127
Score = 37.5 bits (83), Expect = 1.3
Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 4/65 (6%)
Query: 395 ENSISYKKGAGGIRNSNTVEFVVQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVM 454
ENS+ G I + +T ++W+F TG V ++PAL+++ + VGS G + ++
Sbjct: 270 ENSVFIGCDDGNITSLDTRTGALKWSFHTGAPVRSTPALFEN----MIAVGSDDGTLYIL 325
Query: 455 NANTG 459
N +G
Sbjct: 326 NKYSG 330
>UniRef50_Q6HXY8 Cluster: AMP-binding enzyme; n=10; Bacillus cereus
group|Rep: AMP-binding enzyme - Bacillus anthracis
Length = 2345
Score = 86.6 bits (205), Expect = 2e-15
Identities = 91/354 (25%), Positives = 164/354 (46%), Gaps = 20/354 (5%)
Query: 1 MVEILLACTNGASLLIAPD---LTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC 57
++EI L T G+ ++IA + T+ L H + V W++TPS+ ++ L
Sbjct: 464 LLEICLPLTQGSKVVIATEDQFATKELAHLVKKHKVDLWESTPSRMEVILSDPEGANFL- 522
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
LK + L GE + I ++++++ + T I +YG TE + A+V +L +K T
Sbjct: 523 --KDLKSILLAGEAFS-IDLVEKIRCISEAT-ISNIYGPTETTICATVKDLSTSKEVTIG 578
Query: 118 KEVP-----LGNCLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSIKFI 172
K P + N + + F P E G + K L + K + + +
Sbjct: 579 KPNPNYHSYILNKYGQLKPFGIPGELC-IAGVAVARGYLGKSKLTDEKFVPSPFAAGEMM 637
Query: 173 -DTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV---WLQT 227
TGD+ + NG + Y GR+D +K G++I L IE+ + + P + V +
Sbjct: 638 YHTGDLVRWLPNGELEYLGRMDHQVKIRGYRIELREIETQLREYPEINQVIVVDQVYGNR 697
Query: 228 PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK 287
LL Y S +S E+ +L KL E P+K+I+V+ +P N +GK ++ L++I +
Sbjct: 698 KLLAAYYVSDNKVSFGEIRKYLSDKLPEFMIPEKMIQVEEIPLNPNGKVDRKRLLDITQT 757
Query: 288 SNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
+ ++ + ++L K + E + +FF+L G S A+ + N L
Sbjct: 758 DYVSIPYVAPRNEIEQKLVCAWEKVMEIEGIGIHDNFFALKGESIKALQVINLL 811
Score = 54.8 bits (126), Expect = 8e-06
Identities = 77/356 (21%), Positives = 152/356 (42%), Gaps = 27/356 (7%)
Query: 3 EILLACTNGASLLIAPDLTEV--LFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARS 60
+I A + GA L++ D ++ L +T W T P+ + + + + S
Sbjct: 1492 DIFGALSTGAMLVMIRDPRDMQELIRTVERRGITIWNTVPA-IMDLALDQVGSHF--EHS 1548
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
+L+++ G+ + + + +++K + +L G TE S W+ + +V + +
Sbjct: 1549 SLRLVLHSGDWIP-LSLPEKIKRHFPIAEVVSLGGATEASIWSIY--YPVKQVKSHWNSI 1605
Query: 121 PLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE-----NSIKF 171
P G L+ +V +EK +G + + LN + E +
Sbjct: 1606 PYGMPLANQTYYVLNYEKKMCPVGVIGDLYIGGVGLAKGYLNAEKKTNEAFVSHPDFGLI 1665
Query: 172 IDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP-- 228
TGD G++ + G + + GR D +K G+++ L I ++ +V + V QT
Sbjct: 1666 YKTGDCGKMHSEGYIEFLGRQDYQVKIQGYRVELEEISHCLLTYKQVEH-AVVIDQTDEN 1724
Query: 229 --LLLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
L+ Y E +S+ EL L+ L + P + +D LP +GK ++ L
Sbjct: 1725 GIKFLVAYVVTEQNISTTELRKHLRDHLPDYMIPSYFVYLDQLPLTPNGKLDRKALPTPE 1784
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
K+ N + K+ + K L ++ + L + + + FF+LGG S A+ + +L
Sbjct: 1785 KQKNEVFIAP--KTEMEKILTSIWQEVLKIDQVGVNDHFFALGGDSIKAIQVSVRL 1838
>UniRef50_A5N8Z4 Cluster: Predicted hybrid nonribosomal peptide
synthetase/polyketide synthase; n=1; Clostridium kluyveri
DSM 555|Rep: Predicted hybrid nonribosomal peptide
synthetase/polyketide synthase - Clostridium kluyveri DSM
555
Length = 2001
Score = 86.6 bits (205), Expect = 2e-15
Identities = 94/369 (25%), Positives = 172/369 (46%), Gaps = 37/369 (10%)
Query: 1 MVEILLACTNGASLLIAPDLTEVLFHEDND----NSVTFWQTTPSKFFQHSNENIKNKIL 56
++E LL G ++IA + ++ N+ N V Q TPS+ + +
Sbjct: 1419 VLETLLPLCKGLKIIIADENEQIDAKLLNNLIIKNKVDMMQVTPSRLKLLMRGG--SDLT 1476
Query: 57 CARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
C + LK + +GGE L ++L +LK +IF +YG TE + W+ V EL T
Sbjct: 1477 CFKY-LKDVMIGGEALPD-ELLHQLKQVYYG-KIFNMYGPTEATVWSMVKEL------TD 1527
Query: 117 DKEVPLGNCLSETELFVQPHEKNNTM------GKIILASKTRKCILLNRKNGNKEE---N 167
E+ +G +S T++++ +KNN + G++ + LNRK+ KE+ N
Sbjct: 1528 INEISIGKPISNTQIYII--DKNNKLQPIGVSGELCIGGDGVARGYLNRKDLTKEKFFNN 1585
Query: 168 SIKFID----TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
K + TGD+ + + +GTV + GR+D+ +K G++I L IE ++ C ++ C
Sbjct: 1586 PYKVNEKIYRTGDLAKWQPDGTVEFLGRIDNQVKIRGYRIELSEIEKSLGTCKGIKECVV 1645
Query: 223 VWLQTPL---LLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
+ + LI Y+ A+ + +L + + +L + P + + +P +GK K
Sbjct: 1646 ISRENSTGDKYLIAYYVADMEIGVSKLREHMLKELPDYMIPSYFVPIKCMPLTPNGKIDK 1705
Query: 279 EILVNIYKKSNILQ-NVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTI 336
+ L N L+ + + + K+L + L E++ + FF LGG S L V +
Sbjct: 1706 KALPEHDTGRNSLKIEYKAPTTQVEKQLVDIWEDVLEREEVGINDVFFELGGNSLLLVQM 1765
Query: 337 CNKLSLTFP 345
++ +P
Sbjct: 1766 HTRIDKLYP 1774
>UniRef50_Q12Q14 Cluster: Amino acid adenylation; n=1; Shewanella
denitrificans OS217|Rep: Amino acid adenylation -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 1621
Score = 86.2 bits (204), Expect = 3e-15
Identities = 72/293 (24%), Positives = 133/293 (45%), Gaps = 23/293 (7%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
+T + + GGE ++ I++ L K N + +YG TE + W+S +L + +
Sbjct: 1290 TTDQTILCGGEAID-IQLAHLLTEKGNVC--YNMYGPTETTVWSSFKQLSTGDDNSQNSS 1346
Query: 120 VPLGNCLSETELFVQPHEKNNT----MGKIILASKTRKCILLNRKNGNKEE------NSI 169
LG+ ++ T++++ + +G++ + + L+ E N
Sbjct: 1347 TSLGSPIANTQIYILDDALHQVPVGAIGQLWIGGASLSDGYLHNSELTNERFVLHPVNGK 1406
Query: 170 KFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW---L 225
+ TGD+ I G + + GR D +K G +I L IE + Q V + V
Sbjct: 1407 RIYQTGDLASIDGYGELQFHGRADQQVKLSGFRIELEEIEQIIKQLAEVNQVAVVIRNVA 1466
Query: 226 QTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
+TP L I +FS E S L + KL P KVI +DTLP + K K+ L
Sbjct: 1467 ETPQL-IAFFSGECDESTVLTQ-CRQKLPGYMIPHKVITLDTLPLTPNRKVDKKALPTDL 1524
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQS-KSFFSLGGTSFLAVTIC 337
+ S+++ + ++L+ +++ L Y + + ++F+ LGG S +A+ +C
Sbjct: 1525 QPSDVINTPQTPTE---EQLETILSSHLGYPRIDTQRNFYKLGGNSLMAMKVC 1574
>UniRef50_A3DGP7 Cluster: Amino acid adenylation domain; n=1;
Clostridium thermocellum ATCC 27405|Rep: Amino acid
adenylation domain - Clostridium thermocellum (strain
ATCC 27405 / DSM 1237)
Length = 625
Score = 85.8 bits (203), Expect = 4e-15
Identities = 99/392 (25%), Positives = 180/392 (45%), Gaps = 41/392 (10%)
Query: 3 EILLACTNGASLLIAPDLTEV----LFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCA 58
+I + + GAS+++ D L +NS+T Q TPS + K
Sbjct: 225 DIFVPLSAGASIIMVGDCIAKNGTKLIQALEENSITVMQATPSTWRMLLESGWKGN---- 280
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
LK+L GGE L +++ +L K ++ +YG+TE++ ++ ++ KVT+GD
Sbjct: 281 -KQLKILC-GGEALPR-ELVNQLNEKG--AVVWNMYGLTELTVYSVIS-----KVTSGDG 330
Query: 119 EVPLGNCLSETELFVQPHEKN----NTMGKIILASKT------RKCILLNRK---NGNKE 165
VP+G + T+ ++ + +G++ + K L + K N +
Sbjct: 331 PVPIGYPIDNTQAYILDEDLKPVPFGEVGELYIGGDGVGRGYFGKPELTSEKYIQNPFSD 390
Query: 166 ENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW 224
S + TGD+ + +G++ Y GR D IK G +I L IES + + P V+ V
Sbjct: 391 NQSDRICKTGDLARFLPDGSIEYLGRADFQIKLRGFRIELGEIESAIEKHPWVQQAVVVK 450
Query: 225 L--QTPLLLIVYF---SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
+ ++ YF S + SS+++ FLK L + P +++D P +GK ++
Sbjct: 451 DNGEGDQHIVAYFRTKSEQVPSSEDMRSFLKNTLPDYMIPSFFVQIDEFPLTPNGKVDRK 510
Query: 280 ILVNIYKKSNILQNVENIKS-YLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTIC 337
L N K ++ ++ S L KE+ + + L +D+ +F LGG S LA +
Sbjct: 511 SLQNFDYKLDVQRDGYVAPSTSLEKEVAKIWSDLLKIDDIGIYDNFMELGGHSLLANRLT 570
Query: 338 NKLSLTFPEVGKHILPHLLSHNKSIGDVLKTI 369
+++ TF K L +L+ ++ D++K I
Sbjct: 571 LRINDTFGI--KLSLMEVLTSGLTVADMVKLI 600
>UniRef50_A5FI38 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain -
Flavobacterium johnsoniae UW101
Length = 3395
Score = 85.4 bits (202), Expect = 5e-15
Identities = 81/342 (23%), Positives = 155/342 (45%), Gaps = 30/342 (8%)
Query: 18 PDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKV--LALGGEPLNGI 75
P E++++E SVT TP F+ I+ + +C + LK+ + GGE LN
Sbjct: 1529 PGFVELIYNE----SVTILNQTPLAFYNF----IECEKVCPKRDLKLRYIIFGGEALNPA 1580
Query: 76 KILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD----KEVPLGNCLSETEL 131
+L +K ++ +YG+TE + + E+ ++ G K +P +CL E
Sbjct: 1581 -MLSSWHNKYPDAKLINMYGITETTVHVTYKEIGKKEIDLGQSNIGKPIPTLSCLILDEF 1639
Query: 132 FVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSI-------KFIDTGDIGEIR-NG 183
+ +G++ + LNR E + + TGD+G + +G
Sbjct: 1640 --KNIVPAGVIGEMYIGGSGLARGYLNRPELTAERFIVNPFNPEERLYKTGDLGRWQTDG 1697
Query: 184 TVFYRGRVDDTIKRFGHKINLHSIESTVM-QCPRVRS--CSCVWLQTPLLLIVYFSAET- 239
+ Y GR+D+ +K GH+I L IE+ ++ +R L +L+ Y+ ++T
Sbjct: 1698 NIEYIGRIDNQVKIRGHRIELGEIEAVLLGYSSDIRQFVVDTCELNGDKILVAYYVSDTE 1757
Query: 240 LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKS 299
+ L +++ +L E P+ + +D +P +GK +++L + + I ++
Sbjct: 1758 VDKASLRSYIQQQLPEYMVPNFFVAMDAIPLTGNGKVDRKLLPGVIESDLIKTEYTAPRN 1817
Query: 300 YLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKL 340
K L + + L YE + K +F++LGG S ++ I +KL
Sbjct: 1818 EEEKALVEVWTEVLKYEKIGVKDNFYNLGGDSIKSILIISKL 1859
Score = 63.7 bits (148), Expect = 2e-08
Identities = 43/177 (24%), Positives = 86/177 (48%), Gaps = 3/177 (1%)
Query: 167 NSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
N + TGD+ NGT+ + GR D+ +K GH+I L +IE+ + + P V+S +
Sbjct: 637 NQKRIYKTGDLARFMPNGTMEFIGRNDNQVKILGHRIELDAIENIMAEIPAVKSVKAIAD 696
Query: 226 QTPLLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
++++Y+ +++ + + + L KL + P I + + P +GK K L +
Sbjct: 697 TNKQMIVLYYVSDSEIDKNFMEEQLLNKLPKYMLPSAFIHMLSFPLTKNGKIDKTKLPTV 756
Query: 285 YKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
++ ++ ++L + + L + + + +FF LGG S LAV N++
Sbjct: 757 SLDDLAAKDYAAPQNETQEKLAVIWQEVLKIDKVGITDNFFDLGGHSLLAVRAINRI 813
Score = 57.2 bits (132), Expect = 2e-06
Identities = 63/278 (22%), Positives = 125/278 (44%), Gaps = 24/278 (8%)
Query: 84 KNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN---- 139
K++ +I+ YG TE + A+ D T DK VP+G +S ++++ + N
Sbjct: 3080 KDSNLKIYNNYGPTENTVVATY--YDCQSKT--DKNVPIGKPISNVQVYILNDKLNMQPV 3135
Query: 140 NTMGKIILASKTRKCILLNRKNGNKE---ENSIK----FIDTGDIGE-IRNGTVFYRGRV 191
+G++ ++ ++ LN + E EN K TGD+ + +G + + GR+
Sbjct: 3136 GVIGELCISGESLSNGYLNNEELTNEKFIENPFKSGQKIYKTGDLARWLPDGNIEFMGRI 3195
Query: 192 DDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP---LLLIVYFSAETLSSQELLDF 248
D +K G++I L IE ++ ++ + + L+ Y S L + L +
Sbjct: 3196 DGQVKIRGYRIELGEIEKQLLSQEGIKHSVVLVKEIKGEKCLVAYYVSDYELDKKILTEN 3255
Query: 249 LKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKAL 308
L L + P +++D +P + K ++ L ++ I + E I +E K +
Sbjct: 3256 LSKMLPDYMIPAYYVQLDVIPLTTNDKVDRKALPDVDDTDLIRE--EYIAPDTEEEFKLI 3313
Query: 309 V--NKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLT 343
+ L+ + + + +FF+LGG S A+ I ++ T
Sbjct: 3314 EVWKRVLDIDKIGVNDNFFALGGNSIKAMMIIGGINKT 3351
>UniRef50_A3HT12 Cluster: Non-ribosomal peptide synthase; n=1;
Algoriphagus sp. PR1|Rep: Non-ribosomal peptide synthase
- Algoriphagus sp. PR1
Length = 1396
Score = 84.2 bits (199), Expect = 1e-14
Identities = 99/445 (22%), Positives = 192/445 (43%), Gaps = 41/445 (9%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
+LK + L GE +++ K KTR+F YG TE + W +V EL K +V
Sbjct: 747 SLKTVILAGEEFPN-ELIPSHFEKQPKTRLFNEYGPTEGTVWCTVQEL---KAGESFHKV 802
Query: 121 PLGNCLSETELFVQPHEKN----NTMGKIILASK-TRKCILLNRKNGNK------EENSI 169
P+G S +V ++ G++ +A K L + K E
Sbjct: 803 PIGLATSNALAYVLDEQQELSPVGISGELCIAGAGLTKGYLSKSETDEKFLKNPYSEVWD 862
Query: 170 KFIDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL--Q 226
+ TGD+ I ++G + Y GR D+ +K GH+I L I+ +Q P+V+ + +
Sbjct: 863 RIYKTGDLVRIQKDGLIEYLGRKDNQVKIRGHRIELAEIQELALQFPQVQMAVALVSNEK 922
Query: 227 TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
P L++ Y S + L EL+ FL+ KL PD +++++ P +GK + + +
Sbjct: 923 DPQLMLAYTSGQKLEEGELISFLREKLPRFMVPDLLLQLEEFPLLPNGKVDLASIQELAR 982
Query: 287 KSNILQNV--ENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLT 343
+ +YL +++ + + E++ ++ F LGG S ++ I ++
Sbjct: 983 SQPKAAETAFKGPSTYLERQVAGIWADVMGVEEVPVNRDFNELGGNSLQSIRIISRCR-- 1040
Query: 344 FPEVGKHILPHLLSHNKSIGDVLKTI-----TQDTNCLENKFKKSIKRNRSTSSHGENSI 398
+G + P ++ ++K++ + N LE + K ++ G
Sbjct: 1041 --NIGIKVTPAQFLRYSTVESLVKSLHHEEYARPENLLELEVLKIWEKYLGQKLIGVKD- 1097
Query: 399 SYKKGAGGIRNSNTVEFVVQWTFDTGKCVDASPALYK-SESVLYVTVGSHSGKIVVMNAN 457
S++K G VE + +++ K + S ++ + SE V+ K ++
Sbjct: 1098 SFQKNGGAEYEWKLVEKELNDSYEFQKPIQLSDSIQEISEKVV--------NKKGLVELG 1149
Query: 458 TGFIQGLIKLKSR-IEAPILCVHDE 481
+ I+ +I +K+ + P+ C+H E
Sbjct: 1150 SKPIKRIIPVKTTGDKLPVFCIHSE 1174
>UniRef50_Q9LTK8 Cluster: Genomic DNA, chromosome 5, BAC clone:F14A1;
n=4; core eudicotyledons|Rep: Genomic DNA, chromosome 5,
BAC clone:F14A1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 1175
Score = 83.0 bits (196), Expect = 3e-14
Identities = 78/367 (21%), Positives = 153/367 (41%), Gaps = 44/367 (11%)
Query: 419 WTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCV 478
W CVDASP + +S Y+ +GSHS K ++A +G + L+ RIE + V
Sbjct: 775 WKVHMESCVDASPLVVLKDSKTYLFIGSHSRKFSCIDAKSGSMYWETILEGRIEGSAMVV 834
Query: 479 HDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATY--CKGVLYIASYDGN 536
D V+G Y G + S+ W+ IK + +++ S+D
Sbjct: 835 GDFSQV----VIGCYKGKLYFLDFSTGSLCWKFQACGEIKCQPVVDTSSQLIWCGSHDHT 890
Query: 537 IRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTI--IWQGS 594
+ +D + + ++ + + + + SG + + +W
Sbjct: 891 LYALDYRSQCCVYKLQCGGSIFASPAIDEGHSSLYVASTSGRVIAVSIKDSPFHTLWLFE 950
Query: 595 LKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKF 654
L+ PIF + + + V+G++ + G IW Y G IF+ C+ +
Sbjct: 951 LEAPIFGSLCITPSTQ-----NVDGQVIAMS-PSGTIIWRYR-TGGPIFAGPCMSHV--L 1001
Query: 655 KWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTI------------FNDKLIL 702
Q+ C + VYS+ + L W+ + P+ ++ I +D+L+
Sbjct: 1002 PSQVLVCCRNGCVYSLEPES--GCLVWEDNIGDPITASAYIDENLHFESHELLASDRLVT 1059
Query: 703 AASTDGKLWVIH------------SELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLL 750
S+ G++ V+ S++G +T + +L + FSSP++ +F+GCR+D +
Sbjct: 1060 VCSSSGRVHVLRVRPSILSRDSHDSKVGEIT-RMELQADIFSSPVMIGGRIFVGCRDDYV 1118
Query: 751 YSLKIDT 757
+ L +++
Sbjct: 1119 HCLSLES 1125
Score = 54.4 bits (125), Expect = 1e-05
Identities = 77/330 (23%), Positives = 140/330 (42%), Gaps = 38/330 (11%)
Query: 45 QHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMS--C- 101
QH N NK+ +S LK++ L GEP + + L +T LYG TE+S C
Sbjct: 305 QHRGHN--NKL---QSCLKLVVLSGEPFP-VSLWDSLHSLLPETCFLNLYGSTEVSGDCT 358
Query: 102 WASVAELDLNKVTTGDKEVPLGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCIL 156
+ +EL T VP+G +S ++ + +P+E + + L+ +
Sbjct: 359 YFDCSELPRLLKTEEIGSVPIGKSISNCKVVLLGDEDKPYEGEICVSGLCLSQGYMHSSI 418
Query: 157 LNRKNGNKEENSI-----------KFIDTGDIG-EIRNGTVFYRGRVDDTIKRFGHKINL 204
+ NS+ + TGD G ++ +G + + GR D T+K G ++ L
Sbjct: 419 ESEGYVKLHNNSLCNHLTNDCGSQLYYRTGDYGRQLSSGDLIFIGRRDRTVKLNGKRMAL 478
Query: 205 HSIESTVMQCPRVRSCSCVWLQ-----TPLLLIVYFSAETLSSQELL----DFLKCKLDE 255
IE+T+ P + + + L V + E+ SS ++ +++ KL
Sbjct: 479 EEIETTLELNPDIAEAVVLLSRDETELASLKAFVVLNKESNSSDGIIFSIRNWMGGKLPP 538
Query: 256 KYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNV--ENIKSYLFKELKALVNKDL 313
P+ + V+ LP + GK E L + + Q++ N + L + +K V L
Sbjct: 539 VMIPNHFVLVEKLPLTSSGKVDYEALARLKCPTTGAQDMMQSNGTNSLLQNIKKAVCDAL 598
Query: 314 NYEDL-QSKSFFSLGGTSFLAVTICNKLSL 342
+++ FF++GG S A + + L +
Sbjct: 599 LVKEVSDDDDFFAIGGDSLAAAHLSHSLGI 628
>UniRef50_Q8DTJ5 Cluster: Putative bacitracin synthetase 1; BacA; n=1;
Streptococcus mutans|Rep: Putative bacitracin synthetase
1; BacA - Streptococcus mutans
Length = 2724
Score = 82.6 bits (195), Expect = 4e-14
Identities = 79/303 (26%), Positives = 146/303 (48%), Gaps = 27/303 (8%)
Query: 61 TLKVLALGGEPLNGIKILKELK-HKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
+L ++ GE L +++K N+K ++ LYG TE + V D + + ++
Sbjct: 1480 SLSIVFSSGEALTKEQVIKFYSIFDNDKPQLINLYGPTETAI--EVTYFDCSNLDYKSED 1537
Query: 120 VPLGNCLSETELFVQPHEKNN----TMGKIILASKTRKCILLNRKNGNKEE-------NS 168
VP+G L E +V +K +G++ + +N+++ K+ ++
Sbjct: 1538 VPIGEPLDNVEAYVLNDKKQKCPIGVVGELYIGGIQVAQGYINKEDATKKSFVRLPKISN 1597
Query: 169 IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT 227
+ TGD+ + G + + GR DD +K G++I L IE + + + ++C V LQ
Sbjct: 1598 SRLYATGDLVKWTSEGKLIFIGRSDDQVKIRGYRIELGEIEKYLKKVSQ-KNC-LVSLQN 1655
Query: 228 PLL-----LIVYF-SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
L LI Y S+ T+ ++ + LK L + P + V P N GK +++L
Sbjct: 1656 KLSKNNKSLIAYIESSTTIDESKIKEELKTLLPQYMVPSHIYIVPEFPINKSGKVDRKLL 1715
Query: 282 VNIYKKSNILQNVENIK-SYLFKELKALVNKDLNYE-DLQSK--SFFSLGGTSFLAVTIC 337
++Y +I IK S L +++K++ + L+Y D S+ +FFSLGG S A+++
Sbjct: 1716 DSMYSSKHIAPKEGLIKSSNLTEDIKSVWSNILDYSIDSFSEDDNFFSLGGDSIKAISMA 1775
Query: 338 NKL 340
+KL
Sbjct: 1776 SKL 1778
Score = 61.7 bits (143), Expect = 7e-08
Identities = 76/329 (23%), Positives = 135/329 (41%), Gaps = 39/329 (11%)
Query: 94 YGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILAS 149
YG TE + A+ +L+ + +P+G ++ T V ++++ G++ L
Sbjct: 476 YGPTEYTVVATSFKLEKHM-----DNIPIGKPIANTTALVMSNDRHFLPIGFKGELYLGG 530
Query: 150 KTRKCILLN----RKNGNKEENSIK---FIDTGD-IGEIRNGTVFYRGRVDDTIKRFGHK 201
+ LN KN E I F TGD + +G + Y GR+D+ IK G++
Sbjct: 531 DSLSSGYLNDSKKTKNSFIELEQIMGQVFYKTGDLVAYTDSGELLYYGRIDNQIKINGYR 590
Query: 202 INLHSIESTVMQ-CPRVRSCSCVWLQTP----LLLIVYFSAET---LSSQELLDFLKCKL 253
I L IE +++ + CS V + + L ++ T + ++L L KL
Sbjct: 591 IELQDIEKNILEIIGQDSDCSVVVIPVSINGLISLHAFYEGVTGFDSNPNQVLKQLTNKL 650
Query: 254 DEKYWPDKVIRVDTLPTNAHGKTSKEILVNI-YKKSNILQNVENIKSYLFKELKALVNKD 312
P + + P ++GK ++ L I KS ++ + N L K +K +
Sbjct: 651 PSYMVPSTIESLSQFPLTSNGKVDRKYLEKIVLNKSTSVKEINNDNPLLVKVMKIITEIL 710
Query: 313 LNYEDLQSKSFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQD 372
+ + FF +GG S A+ + NKL E+ K + +I D+ K
Sbjct: 711 KGRQINPDEDFFQMGGNSLTAIELANKLQ---EELNKKV---------TIDDIFK-FRNA 757
Query: 373 TNCLENKFKKSIKRNRSTSSHGENSISYK 401
N ++N + + TS ISY+
Sbjct: 758 INLVDNLTNRENLKPLETSIQSSEEISYE 786
>UniRef50_Q9F9L4 Cluster: Micrococcin P1 peptide synthetase; n=1;
Staphylococcus equorum subsp. equorum|Rep: Micrococcin
P1 peptide synthetase - Staphylococcus equorum subsp.
equorum
Length = 915
Score = 82.2 bits (194), Expect = 5e-14
Identities = 81/304 (26%), Positives = 143/304 (47%), Gaps = 30/304 (9%)
Query: 58 ARSTLKVLALGGEPLNGIKILKELKH---KNNKTRIFTLYGVTEMSCWASVAELDLNKVT 114
A S LK + GE L ++ + H N T + LYG TE + V D
Sbjct: 415 AISKLKYVLASGEALKPEQV-NDFNHFIGNKNNTALLNLYGPTETT--VDVTSFDCENHK 471
Query: 115 TGDKEVPLGNCLSETELFVQPHEKNNTMG-----KIILASKTRKCILLNRKNGNKE---E 166
T D +P+G +S + ++ +E NN MG ++ +A LNR +E +
Sbjct: 472 TYDS-IPIGKPISNIQAYIL-NEDNNIMGIGVPGELCIAGVGVTAGYLNRPELTQEKFID 529
Query: 167 NSI---KFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
N K TGD+ + +G + Y GR+D+ +K G++I L IES + Q + +
Sbjct: 530 NPFGKGKLYRTGDLAKWNGDGNIIYIGRIDEQVKIRGYRIELGEIESILRQHTHINDVAI 589
Query: 223 V---WLQTPLLLIVYF-SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
V + L + Y S ++L L L KL + P + ++D LP ++GK +K
Sbjct: 590 VARPMVDNELSICAYLVSDDSLDFGSLKTSLGQKLPDYMIPAYMTQLDELPVTSNGKLNK 649
Query: 279 EILVNIYKKSNI-LQNVENIKSYLFKELKALVNKD-LNYEDLQSKSFFSLGGTSFLAVTI 336
+ L I +S + + +I+S + + +A+++ D ++ D +FF +GG S A+++
Sbjct: 650 KALPEIKVESKVYVAPTNDIESAVAETFEAVLHVDQVSIHD----NFFEMGGHSLKAISV 705
Query: 337 CNKL 340
N++
Sbjct: 706 INEI 709
>UniRef50_A5FI40 Cluster: Amino acid adenylation domain; n=1;
Flavobacterium johnsoniae UW101|Rep: Amino acid
adenylation domain - Flavobacterium johnsoniae UW101
Length = 1992
Score = 81.8 bits (193), Expect = 6e-14
Identities = 76/294 (25%), Positives = 137/294 (46%), Gaps = 21/294 (7%)
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
KVL GGE K+ + ++H N F YG TE+ ++++++ K VP+
Sbjct: 790 KVLITGGESAVYDKVAEFVQHGN----FFNAYGPTEVCVLGTISKIEKGSELLS-KTVPI 844
Query: 123 GNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE---NSIK----F 171
G ++ TE+++ N +G+I + LNR E+ N K
Sbjct: 845 GKPIANTEVYILDEYLNLLPEGAIGEIYITGAGLARGYLNRPELTAEKFIPNPYKEGEIM 904
Query: 172 IDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL--QTP 228
TGD+G+ + +G + Y GR+D+ +K G++I L IE + V+ V Q
Sbjct: 905 YKTGDLGKWLADGNIEYTGRIDEQVKIRGYRIELEEIEKHLSLQDEVKHAVVVVKENQDD 964
Query: 229 LLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK 287
L+ Y+ ++ L ++L L L E P ++V+++ N GK ++ L ++ +
Sbjct: 965 KYLVAYYVSDVELDKRKLQAALGKILPEYMIPGYFVQVESILMNTSGKVDRKALPDVVES 1024
Query: 288 SNILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKL 340
I + ++ K L A ++ L YE + K SFF+LGG S ++ + ++L
Sbjct: 1025 DLIKEEYIAPRTSEEKLLAAAWSEVLKYEKIGVKDSFFNLGGDSIKSIMLISRL 1078
>UniRef50_A5UMM4 Cluster: Serine/threonine protein kinase related
protein; n=1; Methanobrevibacter smithii ATCC 35061|Rep:
Serine/threonine protein kinase related protein -
Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM
861)
Length = 411
Score = 81.8 bits (193), Expect = 6e-14
Identities = 86/352 (24%), Positives = 153/352 (43%), Gaps = 32/352 (9%)
Query: 414 EFVVQ-WTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIE 472
+FV W+F+ V SPA+Y LYV S G + V++ G LK
Sbjct: 46 DFVTNLWSFNMESPVIGSPAIYGD--FLYVV--SQEGILKVIDMENGTEDWSFNLKGDSN 101
Query: 473 APILCVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKG-VLYIA 531
A + V++ VG + + +E+ ++W+ N A Y +Y+
Sbjct: 102 ATPV------VSNNTVFVGN-NQSFKAIDIESQDILWKYNTSDESIQGAAYVDNDTVYVG 154
Query: 532 SYDGNIRCIDILTSTIKETVHV-SDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTII 590
+G+I DI + +D+ +S+ +V+ N + G+ +G C+++N I
Sbjct: 155 CDNGHIYGFDIADGNKTFEADLGNDEIVSSPIVV--NGSLYVGSTNGNVYCINLNNTNIT 212
Query: 591 WQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKE 650
WQ + +++ P Y + K +I ++ + ++ G W Y+ + SS C+ E
Sbjct: 213 WQYATGDAVYSSPA-YADGKIIIGSD-DDSLYALNETNGDLCWDYD-LNNKVKSSPCIDE 269
Query: 651 INKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKL 710
N +Y G + N+ +++ + + W +PV STP I ++LI S DG
Sbjct: 270 YNN---NVYIGSDEGNLTCLDLRD--GTFKWSHATGAPVQSTPAI-KEELIAFGSNDGTG 323
Query: 711 WVIHSELGTVTAQYQLPG------ETFSSPIICDDHVFIGCRNDLLYSLKID 756
+V++ G Y PG E SSP+I + +F + +YSL ID
Sbjct: 324 YVLNKYTGEEEFTYN-PGTILFNSEITSSPVINGNSLFFADHSGHVYSLNID 374
>UniRef50_Q3M5N4 Cluster: Amino acid adenylation; n=1; Anabaena
variabilis ATCC 29413|Rep: Amino acid adenylation -
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length = 1345
Score = 81.4 bits (192), Expect = 8e-14
Identities = 87/331 (26%), Positives = 142/331 (42%), Gaps = 28/331 (8%)
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
+ L +GGE L G K L + KTRI YG TE V E+D +G + +
Sbjct: 730 RALIIGGEALLG-KSLNFWRDNAPKTRIINEYGPTETVVGCCVYEVDEQTSLSG--AILI 786
Query: 123 GNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRK---------NGNKEENSI 169
G ++ T+L++ ++ G++ + LNR N +E +
Sbjct: 787 GRPIANTQLYLLDDKQKLVPIGVPGELYIGGAGVARGYLNRPELTQQRFIPNPFSDEPNS 846
Query: 170 KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP 228
+ TGD+ + +G + Y GR+D +K G +I L IES + Q P V + + + +
Sbjct: 847 RLYKTGDLARYLPDGNIEYLGRIDHQVKIRGFRIELEEIESLLAQHPLVNAVTVIAREDQ 906
Query: 229 -----LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L+ + + +S EL FL+ KL E P + ++ +P HGK ++ L
Sbjct: 907 PGDKRLVGYIVPKEQAPTSSELRQFLQSKLPEYMIPSAFVMLEVIPLTTHGKVDRQALPQ 966
Query: 284 IYKKSNILQNVENI--KSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKL 340
VE I + L +L + LN + K SFF LGG S LAV + +
Sbjct: 967 PDTSRLDTLKVEFIAPRDRLELKLANIWENLLNVHPIGIKDSFFELGGHSLLAVRLMAHI 1026
Query: 341 SLTFPEVGKHILPHLLSHNKSIGDVLKTITQ 371
+ E GK++ L N +I + + Q
Sbjct: 1027 N---QEFGKNLALATLFQNPTIEKLANLLRQ 1054
>UniRef50_Q63CQ7 Cluster: Multifunctional nonribosomal peptide
synthetase; n=1; Bacillus cereus E33L|Rep:
Multifunctional nonribosomal peptide synthetase -
Bacillus cereus (strain ZK / E33L)
Length = 2543
Score = 79.8 bits (188), Expect = 3e-13
Identities = 89/363 (24%), Positives = 155/363 (42%), Gaps = 41/363 (11%)
Query: 1 MVEILLACTNGASLLI--APDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCA 58
+ + L +G ++ I + D L NDN+VT + TPS S N++N
Sbjct: 655 ITSVFLPLVSGLTMKIYQSKDYASALIDLVNDNTVTILKLTPSHMKMISQLNLEN----- 709
Query: 59 RSTLKVLALGGEPLNGIKILKELKHK-NNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
S + +GGE L ++ KE+ K N+ I YG TE + + + ++ +
Sbjct: 710 -SLIHTFIVGGEELT-VQAAKEMTLKINHPISIINEYGPTEATIGCAFHKYNIQN---DN 764
Query: 118 KEVPLGNCLSETELFVQ----PHEKNNTMGKIILASKTRKCILLNRKNGNKEENSIKFID 173
VP+G ++ T+L+V ++ +G++ ++ + C+ N K N KFID
Sbjct: 765 MMVPIGRPINNTQLYVLNSDLQYQPYGVVGELYISGE---CLAYGYYNNPKLTNE-KFID 820
Query: 174 -----------TGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
TGD + ++ N + Y GR+DD IK G +I+L +E + + S
Sbjct: 821 NPFISGEKMYATGDLVYKLPNDNLVYCGRIDDQIKLKGFRIDLGEVEKVLKTESKADEVS 880
Query: 222 CVW--LQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
L L Y S EL + L L + P +I VD +P ++GK K+
Sbjct: 881 VHIRNLNDSEYLCAYLVGSHYSENELKNILGKALPDYMIPTFMINVDNIPLTSNGKVDKK 940
Query: 280 ILVN--IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTIC 337
L + + + + ++ + ++ ++ ED +FF LGG S + I
Sbjct: 941 KLPDPILQSHESYIAPRNGFETAVTDIFSEILGTEVGIED----NFFELGGDSIKGIRII 996
Query: 338 NKL 340
KL
Sbjct: 997 AKL 999
Score = 65.3 bits (152), Expect = 6e-09
Identities = 65/264 (24%), Positives = 117/264 (44%), Gaps = 23/264 (8%)
Query: 90 IFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN---NTMGKII 146
++ YG TE + S ++D N++ V +G ++ ++++ +++ NT+G+I
Sbjct: 2236 VYNTYGPTETTVCCSYFKIDKNQLNN----VSIGRPIANAQMYILANDQLCGINTIGEIC 2291
Query: 147 LASKTRKCILLNRKNGNKEE------NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFG 199
++ LNR ++ K TGD G+ + +GTV Y GR+D+ IK G
Sbjct: 2292 ISGNGVTAGYLNRDELTADKFVPNPYGEGKVYRTGDFGKWMPDGTVTYMGRIDNQIKLRG 2351
Query: 200 HKINLHSIESTVMQCPRVRSCSCVW--LQTPLLLIVYFSAETLSSQELLDFLKCKLDEKY 257
++I L IE + + V + V + ++ VY ++ ++ +E+ LK L
Sbjct: 2352 YRIELGEIEVVIRKKLDVLDVAVVLKKKEEEKIICVYVQSDVVTREEVYKELKANLPIYM 2411
Query: 258 WPDKVIRVDTLPTNAHGKTSK---EILVNIYKKSNILQNVENIKSYLFKELKALVNKDLN 314
P + VD++P +GK EI I E+ + L +AL +
Sbjct: 2412 VPAHIDIVDSIPMKLNGKIDSDQLEIPTIISFNHTNEPMTEDEEKVLSAFTQALEGLSIG 2471
Query: 315 YEDLQSKSFFSLGGTSFLAVTICN 338
D FF +GG S AV + N
Sbjct: 2472 LHD----DFFEVGGHSLKAVRLIN 2491
>UniRef50_Q63CQ6 Cluster: Multifunctional nonribosomal peptide
synthetase; n=1; Bacillus cereus E33L|Rep:
Multifunctional nonribosomal peptide synthetase -
Bacillus cereus (strain ZK / E33L)
Length = 3044
Score = 79.8 bits (188), Expect = 3e-13
Identities = 99/360 (27%), Positives = 171/360 (47%), Gaps = 31/360 (8%)
Query: 40 PSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNK-TRIFTLYGVTE 98
PS F I NK A ++ + L L E + G I K K +K ++++ LYG TE
Sbjct: 684 PSMFRALVEYAIDNKKEEALNSFERLNLVAEKIPGELIGKYNSTKGSKLSKLWNLYGPTE 743
Query: 99 MSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASK-TRK 153
+ ++ +L+ N +P+G +S ++++ H+ + +G+I ++ + K
Sbjct: 744 ATITSTSYQLNENMNLVN---IPIGKPVSNYKVYIL-HKNDLCAQGILGEICISGRGVAK 799
Query: 154 CILLNRKNGNKEENSIK--------FIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINL 204
L N K EE I+ TGDIG I +G V GR+D+ +K G ++ L
Sbjct: 800 GYLNNSKL--TEEVFIRCPAITDEVIYRTGDIGFINPDGEVELVGRMDEQVKIRGFRVEL 857
Query: 205 HSIESTVMQCPRVRSCSCVWLQT--PLLLIVYFSAETLSSQELL-DFLKCKLDEKYWPDK 261
IEST+ V+ V + L+ YF + + ++ D L +L E P+
Sbjct: 858 QEIESTLKGVEGVKEAVVVRQKNLNDDFLVAYFVGDKKVNDLIIKDNLSNRLPEYMVPEF 917
Query: 262 VIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-S 320
+IR+D +P +GK +K++L + K N L E ++ + ++L + + L +E + +
Sbjct: 918 IIRLDEIPLLPNGKINKKLLGEL--KLNKLSKFEEPRNPIEEDLCDVFSIVLGFEKISVN 975
Query: 321 KSFFSLGGTSFLAVTICNKL-SLTFPEVGKHILPHLLSHNKSIGDVLKTITQDTNCLENK 379
SFF LGG S A+ I +KL + K+I+ + + I LK I +DT LE +
Sbjct: 976 TSFFELGGDSIKAIRIVSKLREKGYSSTVKNIMQY--KTVQKIAQTLKEI-KDTKNLEEE 1032
Score = 75.8 bits (178), Expect = 4e-12
Identities = 87/312 (27%), Positives = 139/312 (44%), Gaps = 33/312 (10%)
Query: 53 NKILCARSTLKVLALGGE--PLNGI-KILKELKHKNNKTRIFTLYGVTEMSCWASVAELD 109
N IL LK ++L GE PL+ I + K K NK RI YG TE + ++V E
Sbjct: 2195 NGILYKLHALKSISLAGEAMPLDLISEFFKTSKGIKNKPRIQNCYGPTEATVCSTVYEF- 2253
Query: 110 LNKVTTGDKEVPLGNCLSETELFVQPHEKN---NTMGKIILASKTRKCILLNRKNGNKE- 165
K D V +G + T F+ K +G++ + LN + +KE
Sbjct: 2254 --KEDVNDSRVLVGKPILNTSAFIMNENKLVGIGMIGELFVGGHGVATGYLNNEKLSKEK 2311
Query: 166 ------ENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR 218
E TGD+ +G + GR+ + +K G +I L IES + Q +
Sbjct: 2312 FVDHPYEEGEVLYQTGDLARWNADGNIELFGRIGEQVKIRGFRIELGEIESYIRQVKDIT 2371
Query: 219 SCSCVWLQT---PLLLIVYFSA-ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
S V L T ++ YF+A + + L + L KL++ P+ I++ +P +G
Sbjct: 2372 D-SVVVLDTNDRTEKIVAYFTARKEIDISRLKELLSKKLNDYMVPEHFIQLAGIPKTING 2430
Query: 275 KTSKEIL-----VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGT 329
K K L I+KK +VE F+E+ L+ K+L+ +D +FF +GG
Sbjct: 2431 KIDKRNLPKPSSKRIHKKILPKSDVEKAVYDAFQEV--LLYKELSTDD----NFFDIGGD 2484
Query: 330 SFLAVTICNKLS 341
S A+ + +KL+
Sbjct: 2485 SIKAIRVVSKLN 2496
>UniRef50_A5UTA8 Cluster: Protein kinase; n=5; Chloroflexi
(class)|Rep: Protein kinase - Roseiflexus sp. RS-1
Length = 653
Score = 79.8 bits (188), Expect = 3e-13
Identities = 64/266 (24%), Positives = 116/266 (43%), Gaps = 13/266 (4%)
Query: 489 VVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIK 548
VVG+ DG V + ++ W G ++S V++I S D + ID L
Sbjct: 400 VVGSEDGAVYACDIRRGALRWTFRTGKPVRSSPRVLDRVIFIGSDDQHFYAIDGLRGAQI 459
Query: 549 ETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDN 608
S+ ++ E + FG G L + + W+ + P+ + P +N
Sbjct: 460 WKYRTWMPIRSSGCIVG--ESVYFGGGDGFVYALSIKNGGVRWKQRTQQPVISSPAFAEN 517
Query: 609 DKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVY 668
VI ++ ++ E G +W + + SS V F +++ G D N+Y
Sbjct: 518 --MVIVGSMDNTLYALDSEGGWPVWKFR-TNHYVNSSPYV-----FGTRVFVGGVDGNLY 569
Query: 669 SVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPG 728
+V + N + L WK S + S+P + ++ A+ DG ++ + + GT+ +Y+ G
Sbjct: 570 AVELKNGK--LAWKYDTGSQITSSPRVEQGRVYFGAA-DGCVYCLDAAHGTLIWRYETQG 626
Query: 729 ETFSSPIICDDHVFIGCRNDLLYSLK 754
SSP I + V+IG + LY+L+
Sbjct: 627 PVVSSPAISEGVVYIGSLDHALYALR 652
Score = 72.1 bits (169), Expect = 5e-11
Identities = 58/251 (23%), Positives = 115/251 (45%), Gaps = 17/251 (6%)
Query: 507 VIWQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAK 566
++W+ ++S G++++ YD N+ +D + + ++ IS+ +
Sbjct: 338 LVWRFVCEDEVRSSPCVSNGMVFVGCYDTNLYAVDAGRGEFRWK-YATEGGISSSPAVW- 395
Query: 567 NEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTV 626
N+ ++ G+ G + + W P+ + P + D VIF + + H +
Sbjct: 396 NDIVVVGSEDGAVYACDIRRGALRWTFRTGKPVRSSPRVLDR---VIFIGSDDQ-HFYAI 451
Query: 627 E--KGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTR 684
+ +G +IW Y I SS C+ + + +YFG D VY+++I N + WK R
Sbjct: 452 DGLRGAQIWKYRTWMP-IRSSGCI--VGE---SVYFGGGDGFVYALSIKN--GGVRWKQR 503
Query: 685 VSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIG 744
PV S+P F + +++ S D L+ + SE G +++ SSP + VF+G
Sbjct: 504 TQQPVISSPA-FAENMVIVGSMDNTLYALDSEGGWPVWKFRTNHYVNSSPYVFGTRVFVG 562
Query: 745 CRNDLLYSLKI 755
+ LY++++
Sbjct: 563 GVDGNLYAVEL 573
Score = 49.2 bits (112), Expect = 4e-04
Identities = 53/254 (20%), Positives = 98/254 (38%), Gaps = 20/254 (7%)
Query: 417 VQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPIL 476
++WTF TGK V +SP + + V+++ GS ++ ++G K R PI
Sbjct: 418 LRWTFRTGKPVRSSPRVL--DRVIFI--GSDDQHFYAIDG----LRGAQIWKYRTWMPIR 469
Query: 477 CVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGN 536
C+ G DG V ++N V W+ + S + + ++ + S D
Sbjct: 470 S--SGCIVGESVYFGGGDGFVYALSIKNGGVRWKQRTQQPVISSPAFAENMVIVGSMDNT 527
Query: 537 IRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLK 596
+ +D + S+ V F+ G + G + + + W+
Sbjct: 528 LYALDSEGGWPVWKFRTNHYVNSSPYVFGTRVFV--GGVDGNLYAVELKNGKLAWKYDTG 585
Query: 597 GPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKW 656
I + P + Y F +G ++C G IW Y +G + SS + E
Sbjct: 586 SQITSSPRVEQGRVY--FGAADGCVYCLDAAHGTLIWRYE-TQGPVVSSPAISE-----G 637
Query: 657 QMYFGCHDNNVYSV 670
+Y G D+ +Y++
Sbjct: 638 VVYIGSLDHALYAL 651
>UniRef50_Q4C639 Cluster: Amino acid adenylation; n=1; Crocosphaera
watsonii WH 8501|Rep: Amino acid adenylation -
Crocosphaera watsonii
Length = 2281
Score = 79.4 bits (187), Expect = 3e-13
Identities = 96/382 (25%), Positives = 183/382 (47%), Gaps = 49/382 (12%)
Query: 1 MVEILLACTNGASLLIAPDLTE---VLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC 57
+++I A NGA+L + E L++ + +T + +TP+ +++ E + +K+
Sbjct: 1703 VIDIFSALLNGATLFVFDIKKEGLNSLYNWLETHKITIFHSTPT-VYRYFLEKLGSKVSL 1761
Query: 58 ARSTL---KVLALGGEPL--NGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNK 112
A++ L +++ LGGEP+ +K+ ++ +N + L G TE S + LNK
Sbjct: 1762 AKAQLSHIRLVVLGGEPVLKKDVKLYQQF-FADNCIFVNGL-GATESSFYLQYL---LNK 1816
Query: 113 VTTGDKEV-PLGNCLSETELFVQPHEKNNT--MGKIILAS-----------KTRKCILLN 158
T K++ P+G+ +TE+ + E N T G+I + S + + + L
Sbjct: 1817 KTQIQKQIIPVGSTFEDTEIVLLDEEGNITDLYGEIAVRSPHVALGYWQKEELTQAVFLK 1876
Query: 159 RKNGNKEENSIKFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV 217
G + + TGD G +RN G + GR D+ +K G ++ L IE+ + + P++
Sbjct: 1877 DFQGKDK----RIYRTGDWGRLRNDGVIECLGRKDNQVKIRGFRVELGEIEALLNKHPQI 1932
Query: 218 RSCSCVWLQTPLL---LIVYFSAETLS----SQ-----ELLDFLKCKLDEKYWPDKVIRV 265
+ ++ + L LI Y + +S SQ ++ +FL+ KL P K + +
Sbjct: 1933 KQSVVIYKEDSLREKQLIAYIVPQDISLVSNSQPQIIKQVREFLQEKLPSYMIPAKFVLL 1992
Query: 266 DTLPTNAHGKTSKEILVNIYKKSNILQNVENI--KSYLFKELKALVNKDLNYEDL-QSKS 322
+TLP +GK + IL ++S ++ I +S L +++ + K L E + + +
Sbjct: 1993 ETLPLTPNGKIDRRIL-TAREESEVVVKESFIPPRSPLEEQISNIWQKMLGIELIGVNDN 2051
Query: 323 FFSLGGTSFLAVTICNKLSLTF 344
FF LGG S LA+ + ++ F
Sbjct: 2052 FFDLGGHSLLAIRLLARIEKDF 2073
Score = 54.0 bits (124), Expect = 1e-05
Identities = 80/365 (21%), Positives = 157/365 (43%), Gaps = 45/365 (12%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTL 62
EI + G S+++ + E+ D VT T PS +E IK + ++
Sbjct: 648 EIFVTLGFGGSIIMMENALELPESLHRDK-VTLINTVPSII----SELIK--VNSIPQSV 700
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
K++ L GEPL + I+ +L + +++ LYG +E + + S EL ++T +
Sbjct: 701 KIVTLAGEPLT-VNIVHQLYKIDTIEKVYNLYGSSEDTTY-STCELISKEITDNPS---I 755
Query: 123 GNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE-------ENSIKF 171
G ++ T++++ N G++ + NR K+ E+ K
Sbjct: 756 GRPITNTKIYILDKHFNPVPCGVSGELYIGGDGLARGYFNRPELTKQKFIDSPFEHGQKL 815
Query: 172 IDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV------W 224
TGD+ R +G + + GR+D+ +K G +I L IE+ + ++
Sbjct: 816 YRTGDLASYRKDGKIDFLGRIDNQVKIRGFRIELGEIEAVLNNYVYIKEAKVTSKKDKQG 875
Query: 225 LQTPLLLIVYFSAETLS---SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS---- 277
Q + I+ + + L SQE+ ++L+ KL P + ++ P +GK +
Sbjct: 876 CQQLVAYIILDNKQILCQKISQEIREYLQHKLPAYMIPYVFVPLEYFPLTPNGKINYSAF 935
Query: 278 KEILVNIYKKSNILQN--VENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVT 335
E V+ ++ + I E I + ++ ++ + N +N +FF +GG S L
Sbjct: 936 PEPDVSTFQSNYIAPRTPTEEIIANIWVQVLDIKNVGIN------DNFFEVGGHSLLGTQ 989
Query: 336 ICNKL 340
I +++
Sbjct: 990 IISRI 994
>UniRef50_Q8DTJ7 Cluster: Putative surfactin synthetase; n=1;
Streptococcus mutans|Rep: Putative surfactin synthetase
- Streptococcus mutans
Length = 1628
Score = 79.0 bits (186), Expect = 4e-13
Identities = 76/304 (25%), Positives = 143/304 (47%), Gaps = 30/304 (9%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ + +GG+ + K LK + + KT+ + YG TE + + ++ + +++ GD +P
Sbjct: 273 LEQVIIGGDRASN-KHLKIVMKNSKKTQFYNGYGPTENTVFTTMHNIQYSELE-GD--IP 328
Query: 122 LGNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKNGNK------EENSIK- 170
+G +++T + + K +G++++ LN+K+ ++ IK
Sbjct: 329 IGKAINDTGILIVNENFEEVKKGEVGELVVTGGGLAIGYLNQKDASQGSFISLPNLGIKR 388
Query: 171 FIDTGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL---Q 226
TGD + E +G + + GR D IK G +I L IES + +R C+ +
Sbjct: 389 AYKTGDYVRENNDGDLIFIGRRDSQIKYRGFRIELREIESIAKKIDHIREAICLLIGEKS 448
Query: 227 TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L++ S ++S +++ L +L E P+ +I +D +P +GK + L IY
Sbjct: 449 NSKLVLFAESNSSVSEASIIETLHVELPEYMVPNDLILLDNMPLKLNGKVDSDKLKQIYL 508
Query: 287 KSNILQNVE-----NIKSYLFKELKALVNK-DLNYEDLQSKSFFSLGGTSFLAVTICNKL 340
+ I VE N + + + L+ ++ K +LN E +FF +GG S A I +L
Sbjct: 509 E-KIQSQVEKPSESNTERFFIEILEDVLKKPNLNLE----MNFFEIGGHSLNATIISTRL 563
Query: 341 SLTF 344
S F
Sbjct: 564 SEAF 567
Score = 62.9 bits (146), Expect = 3e-08
Identities = 81/356 (22%), Positives = 157/356 (44%), Gaps = 25/356 (7%)
Query: 3 EILLACTNGASLLIAPDL--TEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARS 60
+I A +GA+L IA T L +N +T W + P+ N K + +
Sbjct: 1248 DIFGALVSGATLTIASQNKDTNYLKKVVQNNPITVWNSVPAYMELICNVLADQKPILS-- 1305
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
++ + L G+ + +++ ++K +F+ G TE S W+ + KV K +
Sbjct: 1306 -IRNIILSGDWIP-LELPLKIKKIFPNANLFSAGGATEGSIWSIY--YPIVKVEPEWKSI 1361
Query: 121 PLGNCLSETELFVQPHEKNN----TMGKIILASKTRKCILLN--RKNGNKEENSIKF--- 171
P G L+ ++++ + N MG I + +N K + N K
Sbjct: 1362 PYGMPLANQQMYILNNMGNELPIGVMGNIYIGGVGVAMGYINDIEKTNDSFINHPKLGRI 1421
Query: 172 IDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLL 230
TGD+G + + G + + GR D +K G++I L I++ + +++ Q
Sbjct: 1422 YKTGDLGRLTSQGYMEFCGRKDIQVKVNGNRIELGEIQAILQSFETIQNAIVTVGQNDYQ 1481
Query: 231 --LIVYFSAETLSSQELLD-FLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK 287
L+ Y+ ++ +++L+ F+K L P I + P ++GK K+ L + KK
Sbjct: 1482 KQLLAYYKSDNEIEKDVLNQFMKQYLPNYMIPSHYIYMSEFPLTSNGKIDKKQLPD-PKK 1540
Query: 288 SNILQNVENI--KSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
++ V+++ K+ L + + + L ++ L + SFFS GG S +A I ++
Sbjct: 1541 IESIKEVKDVKPKNQLEETVLTIWENVLEHQVLSVTDSFFSEGGNSLMATVIIGQI 1596
>UniRef50_A5FI53 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain -
Flavobacterium johnsoniae UW101
Length = 2410
Score = 79.0 bits (186), Expect = 4e-13
Identities = 82/328 (25%), Positives = 146/328 (44%), Gaps = 24/328 (7%)
Query: 52 KNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLN 111
K+ L ++S K++ GGE L + +++++K++ I YG TE + + +DL
Sbjct: 1346 KSLNLKSQSPNKMIIFGGEELT-VDVVEQIKNEKPAITIVNHYGPTETTIGKLLHVVDLE 1404
Query: 112 KVTTGDKEVPLGNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKNGNKEE- 166
+ D+ +P+G S T +FV G++++ LN + +
Sbjct: 1405 N--SYDR-IPIGRPFSNTNVFVVDQNFLLCPVGVEGELVIGGDGVSNGYLNNLQLTETQF 1461
Query: 167 -------NSIKFIDTGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR 218
K TGD + + NG + Y GR DD +K GH+I L I + +
Sbjct: 1462 VKDTLLQTEAKLYKTGDKVKQFPNGDIEYLGRFDDQVKIRGHRIELGEISRNLALIEGIS 1521
Query: 219 SCSCVWLQT--PLLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGK 275
Q LI Y+ +ET L +E+ L L E P +++++LP ++GK
Sbjct: 1522 QSIVTVGQNNEEKFLIAYYVSETQLDKKEIQSSLSKVLPEYMVPSYYVKLESLPLTSNGK 1581
Query: 276 TSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAV 334
+++ L I +K I + ++ ++L + + L E + + +FF+LGG S L V
Sbjct: 1582 INRKALPKISEKDIIRKEYVGPRNKTEEKLVQIWQEILKVETIGVTDNFFNLGGHSLLVV 1641
Query: 335 TICNKLSLTFPEVGKHILPHLLSHNKSI 362
I L+L E+G +I N +I
Sbjct: 1642 RI---LNLIKKEIGLNISVKTFFENPTI 1666
Score = 61.3 bits (142), Expect = 9e-08
Identities = 84/369 (22%), Positives = 151/369 (40%), Gaps = 31/369 (8%)
Query: 4 ILLACTNGASL-LIAPDLTEVLFHEDN---DNSVTFWQTTPSKFFQHS-NENIKNKILCA 58
+ +A NG++L LI + E + N + ++T P+ F S K+K L +
Sbjct: 232 VFMALINGSTLCLINSETKEDIIQLQNWIRNYNITVLHMVPTLFRILSIYSEGKDKNL-S 290
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
LK + L GE L ++ + N T I YG TE + ++ ++
Sbjct: 291 FPDLKYILLAGEKLYNKDVVNWRECHGNNTEIINFYGTTEATILSTFYRIEQELQGELSD 350
Query: 119 EVPLGNCLSETELFVQPHEKNNTMGKI--ILASKTRKCILLNRKNGNKEENSIKFID--- 173
+G +S T + + K N + KI + + + L N E + KFI
Sbjct: 351 VFCVGQPISNTAILIL--NKENKLCKIGEVGSIYIKTPFLTKGYYKNPELTADKFIQNPL 408
Query: 174 ---------TGDIGEIRNG-TVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
TGD G+ + GR D +K G +I++++IE T+++ V C+
Sbjct: 409 TASTDIIYKTGDYGKYDSQRNTIVTGREDGLVKINGVRIDINTIEQTILKLKEVDMVKCL 468
Query: 224 WLQTPLL---LIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
Q LL L+ ++ + ++ ++ L + P + I +D +P NA+GK +
Sbjct: 469 TYQQDLLNVILVCFYKSAAVNENDIRKHCLEYLSQYEMPSRFIALDEVPINANGKIDPVV 528
Query: 281 LVNIYKKSNILQNVENIKSYLFKE----LKALVNKDLNYEDLQSK-SFFSLGGTSFLAVT 335
L I + N E E L + + LN E ++ K ++ LGG S +
Sbjct: 529 LKKIIDDTLAADNNETEDETQADETEQKLIQIWKEILNVEKIRLKDNYLFLGGNSIKLIQ 588
Query: 336 ICNKLSLTF 344
+ ++ F
Sbjct: 589 LRLRIQQNF 597
>UniRef50_UPI00005F995E Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Yersinia
frederiksenii ATCC 33641|Rep: COG1020: Non-ribosomal
peptide synthetase modules and related proteins -
Yersinia frederiksenii ATCC 33641
Length = 1016
Score = 78.6 bits (185), Expect = 6e-13
Identities = 92/367 (25%), Positives = 159/367 (43%), Gaps = 29/367 (7%)
Query: 1 MVEILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARS 60
+ EI A NGA+ +I P +VL +D + + Q T I A
Sbjct: 211 LFEIWGALLNGATTVIIPK-KDVLNIQDFEKEIIRQQITIMFITTALFNLIATTSPRAFR 269
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
L+ L +GGE +N LK + R+F +YG TE + ++ + + +T+G +
Sbjct: 270 FLRNLLVGGETVNP-HTLKLILDAAPPKRLFNVYGPTESTTFSIAYNIQADDLTSGS--I 326
Query: 121 PLGNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKNGNKEE---------- 166
P+G + T F+ +G + + + NR NKE+
Sbjct: 327 PIGQPIDRTLAFILDDRLLPVAQGVIGHLYIGGEGLARGYWNRDELNKEKFVNVTLPGDS 386
Query: 167 NSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
++ TGD+ R +G Y GR+D+ +K GH+I L IE ++ V++ + + +
Sbjct: 387 KPLRLYKTGDLSCQRPDGVFMYHGRMDNQVKLRGHRIELEEIEFQLLNSELVKAATVILV 446
Query: 226 QT----PLL--LIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK- 278
+ P L IV + + L L L E Y ++ V+T+P + GKT K
Sbjct: 447 KNENTDPFLAAFIVPHKPDNFKIKALDKKLHQYLPE-YMLPRLFVVNTIPLTSTGKTDKQ 505
Query: 279 EILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTIC 337
++L+N+ + + ++ E + L L K LN D+ +FF LGG+S A ++
Sbjct: 506 QLLINMEENTVRVERPEVFNDTEY-SLLLLWRKILNKTDINLDDNFFQLGGSSLQAASLI 564
Query: 338 NKLSLTF 344
+L F
Sbjct: 565 IELGRQF 571
>UniRef50_Q8XS39 Cluster: Probable non ribosomal peptide synthetase
protein; n=2; Proteobacteria|Rep: Probable non ribosomal
peptide synthetase protein - Ralstonia solanacearum
(Pseudomonas solanacearum)
Length = 5953
Score = 77.4 bits (182), Expect = 1e-12
Identities = 82/298 (27%), Positives = 135/298 (45%), Gaps = 27/298 (9%)
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
R LK L GGE L G ++ L+ + R++ +YG TE + W+S E+D G
Sbjct: 2953 RPGLKALC-GGEALPG-ELAGRLRARVG--RLWNVYGPTETTIWSSAREVDATDA--GQG 3006
Query: 119 EVPLGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKE-------- 165
VP+G ++ T+++V QP T G++ + LNR E
Sbjct: 3007 VVPIGRPIANTQMYVLDAYRQPVPLGVT-GEVYIGGAGVARGYLNRPELTAERFVENPFH 3065
Query: 166 -ENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV-RSCSC 222
E + TGD+G + +G++ Y+GR D +K G +I L IE+ ++QC V +
Sbjct: 3066 GEGRERMYRTGDLGRWLPDGSLEYQGRADAQVKLRGFRIELGEIEARLLQCAGVSEAVVT 3125
Query: 223 VWLQTP---LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
V P L+ Y S E + +Q L + L+ +L E P +R++ LP +GK ++
Sbjct: 3126 VREDAPGEQRLVAYYVSGEAIEAQTLREQLQSRLPEYMVPAAYVRLERLPLTPNGKLDRK 3185
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTI 336
L ++ E + + L + L E + + FF+LGG S AV +
Sbjct: 3186 ELPAPEGQAYASTAYEAPQGEVEVALAGIWQTLLGVERVGRHDDFFTLGGHSLQAVRL 3243
Score = 62.9 bits (146), Expect = 3e-08
Identities = 73/295 (24%), Positives = 130/295 (44%), Gaps = 26/295 (8%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
++V+ + GE L ++++ L + R++ LYG +E + ++S +D TG +
Sbjct: 3999 VEVVNVAGEALKR-ELVERLFAQTQARRLYNLYGPSETTTYSSWVCMDRQ---TGF-QAH 4053
Query: 122 LGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKE---------EN 167
+G ++ T+++V QP T G+I + LNR E E
Sbjct: 4054 IGRPIANTQIYVLDAYRQPVPLGVT-GEIYIGGAGVARGYLNRPELTAERFVVNPFHGEG 4112
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+G + +G++ Y+GR D +K G +I L IE+ + QC V +
Sbjct: 4113 RERMYRTGDLGRWLPDGSLEYQGRADAQVKLRGFRIELGEIEARLSQCAGVSEAVVTMRE 4172
Query: 227 ----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
L+ Y S E + +Q L + L+ L E P +R++ LP +GK ++ L
Sbjct: 4173 DVPGEQRLVAYYVSGEAIEAQTLREQLQASLPEYMVPAAYVRLERLPLTPNGKLDRKELP 4232
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTI 336
++ E + + L + L E + + FF+LGG S AV +
Sbjct: 4233 APEGQAYASTAYEAPQGEVEVALAGIWQTLLGVERVGRHDDFFTLGGHSLQAVRL 4287
Score = 62.1 bits (144), Expect = 5e-08
Identities = 74/301 (24%), Positives = 132/301 (43%), Gaps = 31/301 (10%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ L +GG+ L+ I L+ + + YG TE + +A+ L + + +P
Sbjct: 816 LRYLMVGGDVLDPATIAMVLR-EGAPQHLLNGYGPTETTTFATT---HLIQAVAAGRGIP 871
Query: 122 LGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKE---------EN 167
+G ++ T+++V QP T G+I + LNR E E
Sbjct: 872 IGRPIANTQIYVLDAYQQPVPLGVT-GEIYVGGAGVGLGYLNRPELTAERFVVNPFHGEG 930
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+G + +G++ Y+GR D +K G +I L IE+++ QC V + +
Sbjct: 931 RERMYKTGDLGRWLPDGSLEYQGRTDAQVKLRGFRIELGEIEASLSQCAGVSEAVVIVRE 990
Query: 227 -TP--LLLIVYF-------SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
TP L+ Y+ S E + +Q L + L+ L E P ++++ LP +GK
Sbjct: 991 DTPGERRLVAYYVSGEANVSGEAIEAQALREQLQASLPEYMVPAAYVKLERLPLTPNGKL 1050
Query: 277 SKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVT 335
+ L ++ + E + + + L + L E + + FF+LGG S AV
Sbjct: 1051 DRRGLPAPEGQAYASKAYEAPQGEVEQTLVGIWQTLLGVERVGRHDDFFALGGHSLQAVR 1110
Query: 336 I 336
+
Sbjct: 1111 L 1111
Score = 57.2 bits (132), Expect = 2e-06
Identities = 46/169 (27%), Positives = 78/169 (46%), Gaps = 6/169 (3%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ----TP 228
TGD+G + +G++ Y+GR D +K G +I L IE+ + QC V +
Sbjct: 1997 TGDLGRWLPDGSLEYQGRADAQVKLRGFRIELGEIEARLSQCAGVSEAVVAMREDVPGEQ 2056
Query: 229 LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L+ Y S E + +Q L + L+ L E P +R++ LP +GK ++ L ++
Sbjct: 2057 RLVAYYVSGEAIEAQTLREQLQASLPEYMVPAAYVRLEHLPLTPNGKLDRKGLPAPDGQA 2116
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTI 336
E + + + L + L E + + FF+LGG S AV +
Sbjct: 2117 YASAAYEAPQGEVEQTLAGIWQTLLGVERVGRHDDFFALGGHSLQAVRL 2165
Score = 49.2 bits (112), Expect = 4e-04
Identities = 44/174 (25%), Positives = 75/174 (43%), Gaps = 6/174 (3%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV----WLQTP 228
TGD+G + +G + Y GR D +K G +I IE+ + C VR + + P
Sbjct: 5173 TGDLGCWQADGNIVYLGRNDHQVKLRGFRIEPGEIEARLAGCEGVREAVVLIRDDGVGEP 5232
Query: 229 LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L+ Y L +Q L L+ L P + ++ +P + GK ++ L +
Sbjct: 5233 RLVAYYSGPAALPAQALRAQLQAALPAYMVPAAYVYLERMPLTSSGKLNRHALPQPTAGA 5292
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLS 341
+ E +S + L ++ L E + + FF+LGG S AV + L+
Sbjct: 5293 YAQHSYEAPRSGIETRLASIWQALLGVETIGRHDDFFALGGNSLQAVRLIGLLA 5346
>UniRef50_Q3IMN6 Cluster: Predicted cell surface protein/
lipoprotein; n=1; Natronomonas pharaonis DSM 2160|Rep:
Predicted cell surface protein/ lipoprotein -
Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)
Length = 377
Score = 77.4 bits (182), Expect = 1e-12
Identities = 76/365 (20%), Positives = 147/365 (40%), Gaps = 23/365 (6%)
Query: 394 GENSISYKKGAGGIRNSNTVEFVVQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVV 453
G +I G G + + V W F+T + +SP + + +YV GS +
Sbjct: 14 GSFAIGVGAGLGIAHRDDVLPSRVVWAFETTGRIVSSPTV--GDGTVYV--GSDDSTVHS 69
Query: 454 MNANTGFIQGLIKLKSRIEAPILCVHDECVTSPCGV-VGTYDGTVI-CFLLENCSVIWQI 511
++ + G + +R+ + + G+ VG+ D + F W+
Sbjct: 70 VSTS----DGTRRTTARLHTKAGVFSSPALGADGGLYVGSTDTAIYGLFSSPGARDEWRF 125
Query: 512 NVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKNEFIL 571
+ + G +Y+ S DG + ++ T + D +S+ V+ ++
Sbjct: 126 ETTDWVTASPAVADGTVYVGSTDGTMYALNAETGAEQWRFETGDGIVSSPAVVDGTVYV- 184
Query: 572 FGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIK 631
G+ G L ++ T WQ +G +++ P + D YV + N I+ G++
Sbjct: 185 -GSTDGTVYALDADSGTDRWQFDTEGRVYSSPTVADGTVYVGSYDAN--IYAIDTTDGVE 241
Query: 632 IWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYS 691
W + +I+SS V E ++ G D +Y+V + S W+ V S
Sbjct: 242 QWQFETGD-SIWSSPTVLEET-----LWIGSKDAALYAVATED--GSEQWRFPTGGEVNS 293
Query: 692 TPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLY 751
+PT+ + + S D L+ + + G+ ++ G SSP + D V++G + LY
Sbjct: 294 SPTVAGET-VYVGSDDANLYAVAASDGSERWTFETGGAVQSSPTVADGTVYVGSGDSTLY 352
Query: 752 SLKID 756
+L D
Sbjct: 353 ALDAD 357
Score = 50.0 bits (114), Expect = 2e-04
Identities = 37/170 (21%), Positives = 73/170 (42%), Gaps = 9/170 (5%)
Query: 589 IIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYN-GAKGNIFSSLC 647
++W G I + P + D YV + +H + G + T K +FSS
Sbjct: 37 VVWAFETTGRIVSSPTVGDGTVYV--GSDDSTVHSVSTSDGTRRTTARLHTKAGVFSSPA 94
Query: 648 VKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTD 707
+ +Y G D +Y + ++ W+ + V ++P + D + STD
Sbjct: 95 LGADGG----LYVGSTDTAIYGL-FSSPGARDEWRFETTDWVTASPAVA-DGTVYVGSTD 148
Query: 708 GKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKIDT 757
G ++ +++E G +++ SSP + D V++G + +Y+L D+
Sbjct: 149 GTMYALNAETGAEQWRFETGDGIVSSPAVVDGTVYVGSTDGTVYALDADS 198
>UniRef50_Q8CUZ9 Cluster: Monomodular nonribosomal peptide synthetase;
n=1; Oceanobacillus iheyensis|Rep: Monomodular
nonribosomal peptide synthetase - Oceanobacillus
iheyensis
Length = 2373
Score = 77.0 bits (181), Expect = 2e-12
Identities = 86/345 (24%), Positives = 152/345 (44%), Gaps = 34/345 (9%)
Query: 33 VTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKE--LKHKNNKTRI 90
VT TPS F+Q + + L + +L+ + GGE L + LK+ H+N+ T++
Sbjct: 1742 VTVLNQTPSAFYQLMYAEQERRDLSRKLSLRYVVFGGEQLE-LARLKDWFTLHENSTTKL 1800
Query: 91 FTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETEL-----FVQP------HEKN 139
+YG+TE + S EL+ + + +G + + E+ F+QP E
Sbjct: 1801 INMYGITETTVHVSYLELNEEIIDQQGNSL-IGTNIPDLEIYILDDFLQPVPIGVTGEMY 1859
Query: 140 NTMGKIILASKTRKCILLNRKNGNK-EENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKR 197
G + + + +R N E + TGD+ + + +GT+ Y GR D +K
Sbjct: 1860 VAGGGLARGYLNQSSLTASRFVANPFGEAGSRMYKTGDLAKWLDDGTIDYIGRSDHQVKI 1919
Query: 198 FGHKINLHSIESTVMQCPRVRSCSCVWLQT--PLLLIVYFSAET-LSSQELLDFLKCKLD 254
G++I L + + ++ ++ + L L+ Y + + +L ++ L
Sbjct: 1920 RGYRIELGEVNAHIISHESIKEAATTVLNQHGDNQLVSYIVTDKEVRDADLKAYIASFLP 1979
Query: 255 EKYWPDKVIRVDTLPTNAHGKTSKEIL------VNIYKKSNILQNVENIKSYLFKELKAL 308
P + +D +P AHGK + L VN+ + + E + LFKE+ L
Sbjct: 1980 GYMIPSTFVHIDRIPLTAHGKLDTKNLPLPDYTVNVTGEGPRTPS-EELLCELFKEILHL 2038
Query: 309 VNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTF-PEVGKHIL 352
++ D SFF LGG S LAVT+ N++ F E+G +L
Sbjct: 2039 --DEVGIHD----SFFDLGGHSLLAVTLMNRIRELFGKELGIGVL 2077
Score = 67.3 bits (157), Expect = 1e-09
Identities = 89/352 (25%), Positives = 157/352 (44%), Gaps = 33/352 (9%)
Query: 1 MVEILLACTNGAS-LLIAPDLTE--VLFHED-NDNSVTFWQTTPSKFFQHSNENIKNKIL 56
++E+ L +GA+ +L+ ++ + +L ++ N+ +T Q TP+ + + I
Sbjct: 661 VLELFLPLVSGATCVLMKREIVQDPILLNQTINNQKITAIQATPTHW-----QMILAHQQ 715
Query: 57 CARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
+ + +K L +GGE L + +K + T LYG TE + W++V ELD + G
Sbjct: 716 ASLTDVKAL-VGGEALPSYLAEEMVKTCQSVTN---LYGPTETTIWSTVYELDKEE-PKG 770
Query: 117 DKEVPLGNC---LSETELFVQPHEKNNTM----GKIILASKTRKCILLNRKNGNK-EENS 168
P+ + + +L + P E + + + R + R N ++
Sbjct: 771 LIGAPIDETAVYVLDQDLQLVPPEVDGELYIAGAGVTRGYYGRPSLTAERYVANPFGDSG 830
Query: 169 IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQ-CPRVRSCSCVWLQ 226
+ TGDI + NG++ Y R DD +K GH+I L IE + P + + V
Sbjct: 831 SRMYRTGDIVQWTSNGSLEYIKRADDQVKLRGHRIELGEIEKVISSFSPNMSAKVIVRED 890
Query: 227 TP--LLLIVYF-SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
TP L+ Y A+ ++ +EL+ K + E PD ++ +D P +GK K+ L
Sbjct: 891 TPGNQQLVAYLVGADEITKEELITHAKHTVPEYMIPDSIVYLDEFPLTLNGKLDKKKLPQ 950
Query: 284 -IYKKSNILQNVENIKSYLFKELKALVNKD-LNYEDLQSKSFFSLGGTSFLA 333
Y + Q + + L L++ ++ ED SFF LGG S LA
Sbjct: 951 PEYYHVEVEQQLNEDEQALHDIFSKLLHLPVISIED----SFFDLGGHSLLA 998
>UniRef50_A7BUB2 Cluster: Non-ribosomal peptide synthetase; n=1;
Beggiatoa sp. PS|Rep: Non-ribosomal peptide synthetase -
Beggiatoa sp. PS
Length = 777
Score = 77.0 bits (181), Expect = 2e-12
Identities = 92/386 (23%), Positives = 174/386 (45%), Gaps = 38/386 (9%)
Query: 13 SLLIAPDLTEVLFHEDN-DNSVTFWQTTPSKFFQHSNENIKNKILCARST------LKVL 65
+LL L + ED+ +N + W HS + ++ + L+++
Sbjct: 142 ALLKGATLYPINIKEDSLENPIKNWLKEQKITLYHSTPTVYRHLISTLTANDHFPKLRLI 201
Query: 66 ALGGEPL--NGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE-VPL 122
LGGE + N + + K+ H + G TE + + +NK T+ + VP+
Sbjct: 202 VLGGEEVYKNDVDVYKQ--HFADDCLFINGLGPTESTV---TLQYFINKQTSNTQATVPV 256
Query: 123 GNCLSETELFV--QPHEKNNTMGKIILASKTRKCILLNRKNGNKE----ENSIKFIDTGD 176
G + ETE+ + + E+ G+I + S + ++ + + + TGD
Sbjct: 257 GYQVVETEIVLLNEAGERTELYGEIGIKSDYVALGYWQKAATTEKAFLTDENRRLYRTGD 316
Query: 177 IGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR-SCSCVWLQTPLL--LI 232
+G +R+ G++ + GR D +K G++I L IE+ + Q P V+ S +W + L L+
Sbjct: 317 MGRLRSDGSLEFLGRKDAQVKLRGYRIELGEIETILNQYPTVQESAVIIWEEQSELKKLV 376
Query: 233 VYFSAETLSSQELLDFLKCK----LDEKYWPDKVIRVDTLPTNAHGKTSKEIL-VNIYKK 287
Y T +S ++ L+C L + P + +D +P +GK ++ +L V +++
Sbjct: 377 AYVVPITKTSTSFVNDLRCFIQGILPDYMVPSGFVILDAIPLLPNGKVNRRLLPVPEFQQ 436
Query: 288 SNILQNVENIKSYLFKELKALVN-KDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTFPE 346
L +++ L K + L+ K + D +FF LGG S LA+T+ +K+ TF
Sbjct: 437 KTYLAPRNSVEQQLCKIWEKLLKVKPIGIHD----NFFDLGGHSLLAITLLSKIEKTF-- 490
Query: 347 VGKHILPHLLSHNKSIGDVLKTITQD 372
GK + L H +I +T++
Sbjct: 491 -GKRLALIELFHAPTIAQQAILLTEE 515
>UniRef50_A6VYF8 Cluster: Amino acid adenylation domain; n=1;
Marinomonas sp. MWYL1|Rep: Amino acid adenylation domain
- Marinomonas sp. MWYL1
Length = 3114
Score = 77.0 bits (181), Expect = 2e-12
Identities = 93/398 (23%), Positives = 183/398 (45%), Gaps = 39/398 (9%)
Query: 1 MVEILLACTNGASLLIAPDLT---EVLFHEDNDNSV-TFWQTTPSKFFQHSNENIKNKIL 56
++EI A NGA L++ D + H ++ V T W T S F ++N +
Sbjct: 558 VLEIWGALLNGAQLVVMGDALFDFSRMEHLITEHQVNTLWLT--SALFDQWSDNAPTSME 615
Query: 57 CARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
C LK L +GG+ +N I ++ K I+ YG TE + ++++ ++ + T
Sbjct: 616 C----LKHLIVGGDRVNPISVVS-FYEKFKDVDIYNGYGPTENTTFSTMFKIPRSTQVT- 669
Query: 117 DKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNR--KNGNK------ 164
D +P+G + ++ +++ + +G+I + LN K+ K
Sbjct: 670 DTSIPIGYPIEQSTVYILDRNQKVLPIGGIGEIYVGGHGVAKGYLNDTVKSDEKFIFDYF 729
Query: 165 EENSI--KFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
+ +S+ + TGD G + G + Y R D +K G +I L IEST+++ R +
Sbjct: 730 KPDSVTGRLYRTGDYGRWKPEGYIDYIARSDGQVKIRGFRIELGEIESTIVKSGFARLAT 789
Query: 222 CVWLQTPLL---LIVYFSAETLS----SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
++ + L YF+ S S ++ D LK L E P ++ ++ +P N +G
Sbjct: 790 VQKIEDESVGSYLAAYFTPLKNSIDNLSDKIRDHLKECLPEYMVPLHIVELEEIPVNVNG 849
Query: 275 KTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLA 333
K SK+ L + K ++ ++ + + K++ ++++ L ++ +FF +GG S LA
Sbjct: 850 KLSKKDLPHPNKCIDLQNHIAPVTD-IEKKVCSVISDVLKITNVGLENNFFLIGGNSILA 908
Query: 334 VTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQ 371
T+ K++ F G + ++ N+ + D+ + + Q
Sbjct: 909 ATLIKKINNGF---GTRLPVDVIFDNQVVADLCRLVEQ 943
Score = 64.9 bits (151), Expect = 8e-09
Identities = 82/385 (21%), Positives = 167/385 (43%), Gaps = 34/385 (8%)
Query: 22 EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKEL 81
E F+ D+ VT TP+ F++ S+ +K L L+ + GGE L +
Sbjct: 1647 EKFFNLCRDSGVTVLNQTPTAFYELSSFALKRNKLDKLDKLQWIIFGGEALKPELLTPWW 1706
Query: 82 K-HKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN- 139
K + ++K ++ +YG+TE + ++ L + V +G L + + +V
Sbjct: 1707 KSYTDSKPQLVNMYGITETTVHVTLKLLKSSDVLVRSN---IGKPLKDVKAYVLDDLGRP 1763
Query: 140 ---NTMGKIILASK-------------TRKCILLNRKNGNK-EENSIKFIDTGDIGE-IR 181
G++ + T + + + N ++ + TGD+ +
Sbjct: 1764 VPPRVPGELFIGGAGIARGYLNDAELTTARFVSASSINFKALADDQARLYKTGDMVRWLV 1823
Query: 182 NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--LLIVYFSAET 239
+G + Y GR D+ +K G +I + +E+ + V C+ + T L+ Y+ +ET
Sbjct: 1824 DGNLEYVGRKDNQVKIRGFRIEIGDVENALSAIDGVNHCAVIVSDTHSHKSLVGYYVSET 1883
Query: 240 ---LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVEN 296
LSS + + KL E P +I ++T+P +GK K+ L N + +
Sbjct: 1884 EKELSSTAIRRVMLEKLPEHMVPSLLINLETMPVTNNGKLDKKALPEPTPLINRKEYIAP 1943
Query: 297 IKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHL 355
++++ E+ +L L+ E++ + +FF LGG S L++ + +++ E G +
Sbjct: 1944 -RNFVESEICSLWEACLDVENVGIRDNFFELGGDSILSIRVISEMR----EKGLELSVKD 1998
Query: 356 LSHNKSIGDVLKTITQDTNCLENKF 380
L ++I ++L I + +K+
Sbjct: 1999 LFRYQTIENILNNIEVSELSINDKY 2023
>UniRef50_Q18559 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 7829
Score = 76.6 bits (180), Expect = 2e-12
Identities = 79/339 (23%), Positives = 152/339 (44%), Gaps = 30/339 (8%)
Query: 53 NKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNK 112
+K + +++ L +GGE ++ + I +K K + R +YG TE W+ + ++
Sbjct: 7273 DKTMSRLESIETLTIGGETVSDVVIETAMK-KFPRLRTIQIYGPTETCIWSLTNKCKVST 7331
Query: 113 VTTGDKEVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSIKFI 172
+ G LG+ LS + N+ G + + K I L R + F
Sbjct: 7332 LNIGSA---LGDSLSNETCTIC---NNSVRGNVQV-----KGISLARGYITSAPHGTPFS 7380
Query: 173 D---TGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL 229
D TGDI + + ++ Y GR+D +K G +IN+ IE ++ C + ++ L
Sbjct: 7381 DIYSTGDIVDSKLNSLQYIGRMDSQVKCKGVRINISEIEKELILCLGLLQIVVLYSNQML 7440
Query: 230 LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK--K 287
+ + L L+ LK + PD ++++ +P N+ GK K +L+ ++ +
Sbjct: 7441 IAFIVDQKSKLLHDSLVKTLK---NRTQIPDYFVQINKMPLNSSGKVDKSLLLQAFENIR 7497
Query: 288 SNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTFPEV 347
+ + + +K+ L +++ + +K L + F S+GG S A+ I ++L+ E+
Sbjct: 7498 KSYKREIVVMKNSLEEKVINVFSKILGRNVAPTDKFESIGGNSLNAIQIAHRLA---EEL 7554
Query: 348 GKHILPHLLSHNKSIGDVLKTITQDTNCLENKFKKSIKR 386
I H + + S LKT N L+N +K I +
Sbjct: 7555 KIEIKAHEILQSNS----LKTF---CNTLKNSVQKPISK 7586
>UniRef50_Q8YTR5 Cluster: Peptide synthetase; n=7; Cyanobacteria|Rep:
Peptide synthetase - Anabaena sp. (strain PCC 7120)
Length = 2588
Score = 76.2 bits (179), Expect = 3e-12
Identities = 98/406 (24%), Positives = 180/406 (44%), Gaps = 56/406 (13%)
Query: 3 EILLACTNGASLLIA----PDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCA 58
EI A NG+ L+I P L E+ T W T F +E++++
Sbjct: 1720 EIWGALLNGSRLVILSNQQPTLAEIGQAITQHQITTLWLTA-GLFHLMVDEHLESL---- 1774
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTE---MSCWASVAELDLNKVTT 115
++K L GG+ L+ + I K L+ + R+ YG TE +C SV ++
Sbjct: 1775 -KSVKQLIAGGDVLSAVHINKLLQ-TYPECRVINGYGPTENTTFTCCYSVTDI------C 1826
Query: 116 GDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEENSIKF 171
VP+G ++ T++++ + N G++ +A LN+ E+
Sbjct: 1827 ESNTVPIGRPINNTQVYILDNHLNPLPVGVPGELYIAGDGLARGYLNQPTLTAEKFINWG 1886
Query: 172 IDTGDIG-----------------EIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQC 214
+ TGD G + +G + Y GR+D+ +K G +I L IE+ + Q
Sbjct: 1887 LGTGDWGLGTTTLSTLYKTGDRARYLADGNIEYLGRLDNQVKIRGFRIELGEIEAVLNQH 1946
Query: 215 PRVRSCSCVWLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
P V+ CV + LI YF A + L +FL+ +L + P + ++TLP +G
Sbjct: 1947 PAVK--ECVVIAREKQLIAYFIALDNTPDNLREFLQQRLPDYLIPHFFVALETLPLTVNG 2004
Query: 275 KTSKEIL----VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTS 330
K ++ L + + + ++ +I++ L + +++N L+ + +FF+LGG S
Sbjct: 2005 KVDRQKLPAPEITSFPDGTVARS--DIEAKLLEIWSSVLN--LSQVSIYD-NFFALGGDS 2059
Query: 331 FLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQDTNCL 376
LA+ + +K + +VG + P L ++I ++ T D + L
Sbjct: 2060 ILAIQLISKAN----QVGLQLTPKQLFQYQTIAELAGVFTVDKSSL 2101
Score = 57.6 bits (133), Expect = 1e-06
Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 9/177 (5%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--- 229
TGD +R+GT+ Y GR+D+ +K G +I L IE+ + Q V++ V +
Sbjct: 853 TGDRARYLRDGTIEYLGRLDNQVKIRGFRIELGEIETVLSQHSEVQAAIVVVTEDTTGDK 912
Query: 230 LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK-- 287
L+ Y +E +L +L L + P + I +D LP +GK + L K
Sbjct: 913 RLVAYIVSENPEITDLRQYLAKNLPDYMIPSQFITLDALPLTPNGKVDRRALPKPQFKTS 972
Query: 288 SNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTF 344
S+ + + L + ++N LN + + +FF+LGG S L + + +++ F
Sbjct: 973 SHTIAPRTPTEELLLNIWQNILN--LNSVGI-TDNFFALGGHSLLVIRLVSQIQQVF 1026
>UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7;
Pseudomonas|Rep: Amino acid adenylation - Pseudomonas
fluorescens (strain PfO-1)
Length = 5422
Score = 76.2 bits (179), Expect = 3e-12
Identities = 79/299 (26%), Positives = 138/299 (46%), Gaps = 24/299 (8%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+++ GGE + + L + RI YG TE + +A+ E+ +V+ + VP
Sbjct: 1877 LRIVLCGGERADPAAFRRLLAEAPD-LRIIHCYGPTETTTYATTFEV--REVSETAESVP 1933
Query: 122 LGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNR---------KNGNKEEN 167
+G +S T+++V QP T G++ + + L+R ++ E+
Sbjct: 1934 IGGPISNTQVYVLDARQQPVPMGVT-GELYIGGQGVALGYLSRPDLTAEKFLQDPFSEQP 1992
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
TGD+ + G + GR DD +K G +I L IE+ ++ C V+ + Q
Sbjct: 1993 GALLYRTGDLARWLAPGQLECIGRNDDQVKIRGFRIELGEIENRLLNCDGVKEAIVLARQ 2052
Query: 227 T---PLLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
PL L+ YF+AE + S L + L+ +L E P +++D LP N +GK ++ L
Sbjct: 2053 DGQEPLRLVAYFTAEKGVDSASLREQLQARLPEYMVPSAWVQLDALPLNNNGKVDRKALP 2112
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + Q E + + L + L E + + +FF LGG S LAV++ +L
Sbjct: 2113 LPDPSAWLSQAYEAPQGPVETALAQIWVDVLKLEKVGRHDNFFELGGHSLLAVSLIERL 2171
Score = 61.7 bits (143), Expect = 7e-08
Identities = 47/170 (27%), Positives = 84/170 (49%), Gaps = 5/170 (2%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLLLI 232
TGD+ + +G + Y GR DD +K G ++ L IE+ + P V+ V L L+
Sbjct: 3066 TGDLARWLADGNIEYLGRNDDQVKLRGVRVELGEIEAALASHPAVQDA--VALVRDGQLL 3123
Query: 233 VYFSAETLSSQELL-DFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNIL 291
V+F+ + E L + L+ +L + P +R+D LP A+GK +++L + + +
Sbjct: 3124 VWFTERAPADIEALRNHLQTRLPQALIPAAYVRLDALPLTANGKLDRKVLPEPDQNAWLS 3183
Query: 292 QNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + + L + L E + + +FF LGG S LAV++ +L
Sbjct: 3184 REYAAPQGPMETALAQIWADVLKLEKVGRHDNFFELGGHSLLAVSLIERL 3233
Score = 58.0 bits (134), Expect = 9e-07
Identities = 70/297 (23%), Positives = 126/297 (42%), Gaps = 18/297 (6%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S L+ + GE L G +++ K + + + LYG TE + + + TT D
Sbjct: 5096 SALRQVMCSGEALPG-SLVRRFKQQLPGSGLHNLYGPTEAAVDVTAWDCAGPIETTPDN- 5153
Query: 120 VPLGNCLSETELFV----QPHEKNNTMGKIILASKTRKCILLNRKNGNKE-------ENS 168
P+G ++ T L++ Q +G++ + LNR + E + +
Sbjct: 5154 TPIGKPIANTRLYILDAQQQPVPQGVVGELYIGGVQVARGYLNRPELSAERFLNDPFKPN 5213
Query: 169 IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT 227
+ TGD+ + +G + Y GR DD +K G +I L I+S + V+ + +
Sbjct: 5214 GRMYRTGDVARYLADGNIEYLGRNDDQVKIRGLRIELGEIQSRLTDISGVQEAVVLARED 5273
Query: 228 ---PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
L+ Y++ L L L L + P + + LP + +GK ++ L
Sbjct: 5274 VPGDKRLVAYYTGARLVIDVLRGHLLEHLPDYMVPAVFVHLGALPLSPNGKLDRKALPAP 5333
Query: 285 YKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + I + E + L L + LN E + + +FF LGG S LAV++ +L
Sbjct: 5334 DQSAAITREYEAPVGEVEILLAGLWAELLNVERVGRHDNFFELGGHSLLAVSLIGRL 5390
Score = 57.6 bits (133), Expect = 1e-06
Identities = 69/309 (22%), Positives = 135/309 (43%), Gaps = 22/309 (7%)
Query: 50 NIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELD 109
+++N C T V GGE ++ ++++ + + R+ +YG TE + +SV L+
Sbjct: 796 DVENVSQCTSLT-DVFCGGGELTP--ELGRQVRERLPQVRLHNVYGPTETTVDSSVWTLE 852
Query: 110 LNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE 165
+ + + +P+G +S T L++ + G++ + LN + E
Sbjct: 853 PS-MPVPEALLPIGRPVSNTRLYILDEQLQPLPLGVAGELYIGGVQVARGYLNLASLTAE 911
Query: 166 ---------ENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCP 215
+ + + TGD+ R +G + Y GR DD +K G +I L I++ + Q
Sbjct: 912 RFLDDPFSDQPNARLYRTGDLCRYRADGNLEYLGRNDDQVKVRGLRIELGEIQTRLTQLA 971
Query: 216 RVRSCSCVWLQTPL---LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNA 272
V + + + L+ Y++ L EL L +L + P + + +P +
Sbjct: 972 TVLAAEVLVREDVAGDPRLVAYYTGGPLEIGELRSHLLEQLPDYMVPTAFVHLAAMPLSP 1031
Query: 273 HGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSF 331
+GK ++ L + S IL+ E + + + LN E + + +FF LGG S
Sbjct: 1032 NGKLDRKALPAPDQSSQILRGYEAPVGDVECRIAEIWQALLNVERVGRHDNFFELGGHSL 1091
Query: 332 LAVTICNKL 340
LAV + ++
Sbjct: 1092 LAVKLVERM 1100
Score = 53.2 bits (122), Expect = 2e-05
Identities = 69/298 (23%), Positives = 133/298 (44%), Gaps = 21/298 (7%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S+L + GG L + + ++ + + R+ +YG TE + ++V L+ + + D
Sbjct: 4018 SSLTDVFCGGGDLTPA-LARLVRERLPQVRLHNVYGPTEATVDSTVWTLEPS-MAVPDSA 4075
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIIL--ASKTRKCILLNRKNGNKEENSI---- 169
+P+G ++ T L+V K +G++ + A R + L + + S
Sbjct: 4076 LPIGRPINNTRLYVLDAAKRPVPMGVIGQLFIGGAGVARGYLGLPQLMAERFTPSPFVAG 4135
Query: 170 -KFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT 227
+ TGD+ R +G + + GR D +K G ++ IE+ ++ P +R V L
Sbjct: 4136 DRLYATGDLVRYRADGQLEFIGRNDFQVKLRGLRLEPGEIEAQLLSHPALREA--VVLVR 4193
Query: 228 PLLLIVYFSAETLSSQE----LLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L+ YF+ + Q L + L +L + P + +D+LP + +GK ++ L
Sbjct: 4194 EERLVAYFTWHAEAGQPGIEALREHLLARLPDYMVPSAFVALDSLPLSPNGKVDRKALPA 4253
Query: 284 IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+S +++ E L L + L E + + FF LGG S LAV++ ++
Sbjct: 4254 PGAESVLVREYEPPVGETEIALARLWAEVLKVERVGRHDHFFELGGHSLLAVSLIERM 4311
>UniRef50_Q0W5H8 Cluster: Putative uncharacterized protein; n=1;
uncultured methanogenic archaeon RC-I|Rep: Putative
uncharacterized protein - Uncultured methanogenic
archaeon RC-I
Length = 429
Score = 76.2 bits (179), Expect = 3e-12
Identities = 64/253 (25%), Positives = 115/253 (45%), Gaps = 21/253 (8%)
Query: 509 WQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKETVHVSDQ---AISADLVLA 565
W + + I Y VLY+ + G + + + + T ++ AISA ++A
Sbjct: 34 WTYSTNAYITGSPVYQNNVLYVGTQSGKLYSLYAPYGSAQWTFTTDNKTPTAISAAPLVA 93
Query: 566 KNE-----FILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGE 620
+E I FG+ G + +N K + W+ I PVLY+ + F NG+
Sbjct: 94 TDEVTRQRMIYFGSGQGTLFAVDINGKEV-WRFQADSSIDCTPVLYNG--VIFFGTFNGK 150
Query: 621 IHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLH 680
++ + E G + W + A G I L + Q+YFG D ++YS+++ N + L
Sbjct: 151 VYALSAEDGNQCWNFT-ADGWISDGLAAMDN-----QIYFGSWDGHLYSLDVGNGKQKL- 203
Query: 681 WKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDH 740
K ++S V + P + D I + DG L+ I+ G V +++ G S P++ +
Sbjct: 204 -KVDLNSRV-NAPVVSGDN-IYVGTQDGVLYCINRFSGNVQWKFETDGAIVSRPLVQLNT 260
Query: 741 VFIGCRNDLLYSL 753
V+ G + LY++
Sbjct: 261 VYFGSADGNLYAV 273
Score = 71.7 bits (168), Expect = 7e-11
Identities = 80/322 (24%), Positives = 138/322 (42%), Gaps = 23/322 (7%)
Query: 418 QWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLI----KLKSRIEA 473
+WT+ T + SP +Y++ +VLYV G+ SGK+ + A G Q K + I A
Sbjct: 33 EWTYSTNAYITGSP-VYQN-NVLYV--GTQSGKLYSLYAPYGSAQWTFTTDNKTPTAISA 88
Query: 474 PILCVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASY 533
L DE G+ GT+ + N +W+ S I GV++ ++
Sbjct: 89 APLVATDEVTRQRMIYFGSGQGTLFAVDI-NGKEVWRFQADSSIDCTPVLYNGVIFFGTF 147
Query: 534 DGNIRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQG 593
+G + + + +D IS L N+ I FG+ G L V +
Sbjct: 148 NGKVYALSAEDGN-QCWNFTADGWISDGLAAMDNQ-IYFGSWDGHLYSLDVGNGKQKLKV 205
Query: 594 SLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINK 653
L + A PV+ ++ YV +G ++C G W + G I S V ++N
Sbjct: 206 DLNSRVNA-PVVSGDNIYV--GTQDGVLYCINRFSGNVQWKFE-TDGAIVSRPLV-QLN- 259
Query: 654 FKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVI 713
+YFG D N+Y+VN TN + WK + + +TP F+ ++ S+DG ++ +
Sbjct: 260 ---TVYFGSADGNLYAVNETNGRQI--WKFAAQNGIRATPG-FDSGILYFGSSDGHVYAV 313
Query: 714 HSELGTVTAQYQLPGETFSSPI 735
+ +G +Y ++P+
Sbjct: 314 DARMGLEYWRYNAGSAVDTTPM 335
Score = 41.5 bits (93), Expect = 0.081
Identities = 40/180 (22%), Positives = 72/180 (40%), Gaps = 12/180 (6%)
Query: 445 GSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCVHDECVTSPCGVVGTYDGTVICFLLEN 504
GS G + ++ G + + L SR+ AP+ V+ VGT DG + C +
Sbjct: 185 GSWDGHLYSLDVGNGKQKLKVDLNSRVNAPV-------VSGDNIYVGTQDGVLYCINRFS 237
Query: 505 CSVIWQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVL 564
+V W+ I S+ +Y S DGN+ ++ T+ + + I A
Sbjct: 238 GNVQWKFETDGAIVSRPLVQLNTVYFGSADGNLYAVN-ETNGRQIWKFAAQNGIRATPGF 296
Query: 565 AKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVL---YDNDKYVIFAEVNGEI 621
+ + FG+ G + W+ + + P+ D K++ FA VNG++
Sbjct: 297 -DSGILYFGSSDGHVYAVDARMGLEYWRYNAGSAVDTTPMAGLGTDRKKHLYFATVNGDV 355
>UniRef50_P39846 Cluster: Peptide synthetase 2; n=5; Bacillus|Rep:
Peptide synthetase 2 - Bacillus subtilis
Length = 2560
Score = 76.2 bits (179), Expect = 3e-12
Identities = 77/365 (21%), Positives = 163/365 (44%), Gaps = 32/365 (8%)
Query: 33 VTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFT 92
VT TP+ F+ E+ + ++ + GGE L +L+ K T +
Sbjct: 1732 VTVLNQTPTAFYGLMLEDQNHT---DHLNIRYVIFGGEALQP-GLLQSWNEKYPHTDLIN 1787
Query: 93 LYGVTEMSCWA-----SVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKNNTMGKIIL 147
+YG+TE + S A++ NK G L + + + +QP G++ +
Sbjct: 1788 MYGITETTVHVTFKKLSAADIAKNKSNIGRPLSTLQAHVMDAHMNLQP---TGVPGELYI 1844
Query: 148 ASKTRKCILLNRKN-------GNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFG 199
+ LNR N + TGD+ + + NG + Y GR+D+ +K G
Sbjct: 1845 GGEGVARGYLNRDELTADRFVSNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDEQVKVRG 1904
Query: 200 HKINLHSIESTVMQCPRVRSCSCVWL-----QTPL-LLIVYFSAETLSSQELLDFLKCKL 253
H+I L I++ ++Q P ++ + + QT + +V + + ++ +LK L
Sbjct: 1905 HRIELGEIQAALLQYPMIKEAAVITRADEQGQTAIYAYMVIKDQQAANISDIRTYLKNAL 1964
Query: 254 DEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDL 313
+ P ++I++D++P +GK ++ L K++ ++ + ++ + + + + L
Sbjct: 1965 PDFMLPARMIQIDSIPVTVNGKLDQKALPEPEKQAYTADDI-SPRNEIETVMAEIWEELL 2023
Query: 314 NYEDL-QSKSFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQD 372
N ++L S +FF LGG S A+ +C +L + G + ++++G++ + +D
Sbjct: 2024 NVDELGVSANFFKLGGDSIKALQVCARLK----QRGFETTVREMFEHQTLGELSARVRKD 2079
Query: 373 TNCLE 377
++
Sbjct: 2080 VRAID 2084
Score = 53.6 bits (123), Expect = 2e-05
Identities = 43/173 (24%), Positives = 77/173 (44%), Gaps = 8/173 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--- 229
TGD G + +GT+ Y GR DD +K G++I L IE+ + Q P V+ + +
Sbjct: 840 TGDAGRFLPDGTIEYIGRFDDQVKIRGYRIELREIETVLRQAPGVKEAAVLARDVSAEEK 899
Query: 230 LLIVYFSAETLSS-QELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L+ Y E +S +L L L P +I + +P + GK + L +
Sbjct: 900 ELVAYIVPEKGNSLPDLYQHLAGTLPSYMIPASIINISQMPLTSSGKLDRFALPEPENNT 959
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKL 340
++ ++ + +L + LN + + + FF LGG S A + +++
Sbjct: 960 SVTYMAP--RTLIEADLAHIWEDVLNKQHIGIRDDFFQLGGQSLKAAALVSRI 1010
>UniRef50_UPI00015978D8 Cluster: NrsC; n=1; Bacillus amyloliquefaciens
FZB42|Rep: NrsC - Bacillus amyloliquefaciens FZB42
Length = 3411
Score = 75.8 bits (178), Expect = 4e-12
Identities = 78/365 (21%), Positives = 168/365 (46%), Gaps = 38/365 (10%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHED--NDNSVTFWQTTPSKF-----FQHSNENIKNKI 55
+I A + GA+L++ D ++ D + +T W + P + EN N
Sbjct: 739 DIFGAFSAGATLVMIEDQRDIKKIHDIVKEEKITVWNSVPMIMEMLVNYMDETENKSNAG 798
Query: 56 LCARSTL---KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNK 112
+ L +++ L G+ + + + + +K ++ + +L G TE S W+ + K
Sbjct: 799 VINYDELPELRLVLLSGDWIP-VHLPERIKDHFVESEVISLGGATEASIWSIYYPIKTVK 857
Query: 113 VTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEENS 168
+P G LS +V +E + G++ + K LN +KE+
Sbjct: 858 AEW--TSIPYGYPLSNQTYYVLNYENDPCPIGVKGELFIGGKGVAEGYLN----DKEKTE 911
Query: 169 IKFID---------TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR 218
FID TGD+G + + G + + GR D IK G+++ L IES +++ +VR
Sbjct: 912 ASFIDHPDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVRGYRVELGEIESVILEHRQVR 971
Query: 219 SCSCVWLQTPL---LLIVYFSA-ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
+ + + +L Y + ++L +L +FL K+ E P +++++ +P ++G
Sbjct: 972 NAVVINQKDARNQDVLYAYVAGHQSLPPTDLKEFLSLKVPEYMIPSYIVQIEEVPLTSNG 1031
Query: 275 KTSKE--ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSF 331
K ++ + +++ +++I + ++ ++ + ++L + L +++ +FF LGG S
Sbjct: 1032 KVDRKKLLALDVTDQASIGRKIKEPRTEIERDLVGIWKSVLKTDEISIDDNFFELGGNSI 1091
Query: 332 LAVTI 336
L + +
Sbjct: 1092 LIINL 1096
Score = 75.8 bits (178), Expect = 4e-12
Identities = 78/365 (21%), Positives = 168/365 (46%), Gaps = 38/365 (10%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHED--NDNSVTFWQTTPSKF-----FQHSNENIKNKI 55
+I A + GA+L++ D ++ D + +T W + P + EN N
Sbjct: 1787 DIFGAFSAGATLVMIEDQRDIKKIHDIVKEEKITVWNSVPMIMEMLVNYMDETENKSNAG 1846
Query: 56 LCARSTL---KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNK 112
+ L +++ L G+ + + + + +K ++ + +L G TE S W+ + K
Sbjct: 1847 VINYDELPELRLVLLSGDWIP-VHLPERIKDHFVESEVISLGGATEASIWSIYYPIKTVK 1905
Query: 113 VTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEENS 168
+P G LS +V +E + G++ + K LN +KE+
Sbjct: 1906 AEW--TSIPYGYPLSNQTYYVLNYENDPCPIGVKGELFIGGKGVAEGYLN----DKEKTE 1959
Query: 169 IKFID---------TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR 218
FID TGD+G + + G + + GR D IK G+++ L IES +++ +VR
Sbjct: 1960 ASFIDHPDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVRGYRVELGEIESVILEHRQVR 2019
Query: 219 SCSCVWLQTPL---LLIVYFSA-ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
+ + + +L Y + ++L +L +FL K+ E P +++++ +P ++G
Sbjct: 2020 NAVVINQKDARNQDVLYAYVAGHQSLPPTDLKEFLSLKVPEYMIPSYIVQIEEVPLTSNG 2079
Query: 275 KTSKE--ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSF 331
K ++ + +++ +++I + ++ ++ + ++L + L +++ +FF LGG S
Sbjct: 2080 KVDRKKLLALDVTDQASIGRKIKEPRTEIERDLVGIWKSVLKTDEISIDDNFFELGGNSI 2139
Query: 332 LAVTI 336
L + +
Sbjct: 2140 LIINL 2144
Score = 74.9 bits (176), Expect = 7e-12
Identities = 79/376 (21%), Positives = 171/376 (45%), Gaps = 38/376 (10%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHED--NDNSVTFWQTTPSKF-----FQHSNENIKNKI 55
+I A + GA+L++ D ++ D + +T W + P + EN N
Sbjct: 2835 DIFGAFSAGATLVMIEDQRDIKKIHDIVKEEKITVWNSVPMIMEMLVNYMDETENKSNAG 2894
Query: 56 LCARSTL---KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNK 112
+ L +++ L G+ + + + + +K ++ + +L G TE S W+ + K
Sbjct: 2895 VINYDELPELRLVLLSGDWIP-VHLPERIKDHFVESEVISLGGATEASIWSIYYPIKTVK 2953
Query: 113 VTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEENS 168
+P G LS +V +E + G++ + K LN +KE+
Sbjct: 2954 AEW--TSIPYGYPLSNQTYYVLNYENDPCPIGVKGELFIGGKGVAEGYLN----DKEKTE 3007
Query: 169 IKFID---------TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR 218
FID TGD+G + + G + + GR D IK G+++ L IES +++ +VR
Sbjct: 3008 ASFIDHPDFGRIYRTGDMGVLTQEGYIEFLGRKDHQIKVRGYRVELGEIESVILEHRQVR 3067
Query: 219 SCSCVWLQTPL---LLIVYFSA-ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
+ + + +L Y + ++L +L +FL K+ E P +++++ +P ++G
Sbjct: 3068 NAVVINQKDARNQDVLYAYVAGHQSLPPTDLKEFLSLKVPEYMIPSYIVQIEEVPLTSNG 3127
Query: 275 KTSKE--ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSF 331
K ++ + +++ +++I + ++ ++ + ++L + L +++ +FF LGG S
Sbjct: 3128 KVDRKKLLALDVTDQASIGRKIKEPRTEIERDLVGIWKSVLKTDEISIDDNFFELGGNSI 3187
Query: 332 LAVTICNKLSLTFPEV 347
I K+ + ++
Sbjct: 3188 SLSNIYTKIEKKYSDL 3203
>UniRef50_Q12Q13 Cluster: Amino acid adenylation; n=1; Shewanella
denitrificans OS217|Rep: Amino acid adenylation -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 3137
Score = 75.8 bits (178), Expect = 4e-12
Identities = 93/398 (23%), Positives = 180/398 (45%), Gaps = 37/398 (9%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTL 62
EI + + G S+ A + + L + + ++++ PS E +K++ L S++
Sbjct: 2753 EIFITWSLGGSVYFAENSLQ-LVDDMHKHAISLLNVVPSIL----TEVLKHQSLS--SSI 2805
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
+++ L GEPL + K L ++ R+F LYG +E + +++ E++ K ++ +
Sbjct: 2806 RIVNLAGEPLPP-SLAKALYKQSEHIRVFNLYGPSEDTTYSTWFEVEKEKCD----DMLI 2860
Query: 123 GNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKNGNKEE-----NSIKFID 173
G L T+ + H + +G++ L+ + N+ + N+E N F
Sbjct: 2861 GQPLPGTQAIISDHSGRLLPDYFVGELYLSGRGLAKGYWNKPDLNEERFIRHNNGQVFYK 2920
Query: 174 TGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV-RSCSCVWL--QTPL 229
TGD + + + Y GR+DD +K G +I L I V+ +V SC+ V T
Sbjct: 2921 TGDLVRRVEQQQLEYIGRIDDQVKLRGFRIELEEISHLVLADEQVLASCTLVIKHDDTDQ 2980
Query: 230 LLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK- 287
++ + S E ++ L + LK L P +++ +PT GK K+ L ++K
Sbjct: 2981 IVCFFVSDERDVNINRLKERLKKNLPNYMVPTHFQQIEKMPTTPSGKQDKKALNTLFKPY 3040
Query: 288 SN--ILQNVENIKSYL----FKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLS 341
SN + + +N Y+ + L +K + YE FF GGT LA ++ N++
Sbjct: 3041 SNCAVTDDEQNHSEYVQWCCSQFTSFLPDKKVGYE----SDFFESGGTPSLASSLLNRIR 3096
Query: 342 LTFPEVGKHILPHLLSHNKSIGDVLKTITQDTNCLENK 379
F S+ S+G++++++ + L N+
Sbjct: 3097 TDFSVKISFEKLSSNSNPVSLGELIESLIELQEELNNE 3134
>UniRef50_A3INW9 Cluster: Amino acid adenylation; n=1; Cyanothece sp.
CCY 0110|Rep: Amino acid adenylation - Cyanothece sp. CCY
0110
Length = 1092
Score = 75.8 bits (178), Expect = 4e-12
Identities = 81/302 (26%), Positives = 135/302 (44%), Gaps = 23/302 (7%)
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
K L LGGE N +++K++K I+ YG TE + + ++ + VPL
Sbjct: 731 KRLILGGEASNW-QLIKKIKQYAPDCCIYNHYGPTETTIGVLTYSVTSDEPVSDLNTVPL 789
Query: 123 GNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKE-------ENSIK 170
G L T++++ QP T G++ + LN+ +E + K
Sbjct: 790 GTPLPNTQMYILDRYLQPVPIGVT-GELYIGGDNLSRGYLNQPELTEERFIENPFDKQTK 848
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV-WLQTP 228
TGD+ +GT+ + GR D IK G +I L +E T+ Q P+++ W +P
Sbjct: 849 LYKTGDLARYFPDGTIEFLGRSDRQIKIRGFRIELGEVEGTLRQHPQIQEAVVTSWEASP 908
Query: 229 ----LLLIVYFSAETLSSQELLD-FLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L+ + S E E+L+ FL KL + P + +DT P +GK + + L +
Sbjct: 909 GNPRLVAYLISSEEEKPENEILNHFLAQKLSDFMIPSHFLWLDTFPLTPNGKINYKALPS 968
Query: 284 IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLSL 342
SN N K+ + + L + L+ E + + SFF LGG S LA + +++
Sbjct: 969 -PDTSNSQTNYIAPKTAIEEILCNIWQDLLSLEKVGVNHSFFDLGGHSLLATQLISRIRQ 1027
Query: 343 TF 344
TF
Sbjct: 1028 TF 1029
>UniRef50_Q7MZA9 Cluster: D-alanine-activating enzyme; n=1;
Photorhabdus luminescens subsp. laumondii|Rep:
D-alanine-activating enzyme - Photorhabdus luminescens
subsp. laumondii
Length = 487
Score = 75.4 bits (177), Expect = 5e-12
Identities = 69/279 (24%), Positives = 132/279 (47%), Gaps = 22/279 (7%)
Query: 21 TEVLFHEDNDNSVTFWQTTPS-KFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILK 79
+E + N T W +TPS + Q +++ +L LK GE L+ ++K
Sbjct: 214 SEKFYQVLNHYQPTVWVSTPSFSYKQLLSQSFNYSLL---KNLKHFLFCGEILSK-NLVK 269
Query: 80 ELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN 139
L+ + I+ YG TE + ++ E+ + + + +P+G S + L ++
Sbjct: 270 HLRKRFPSAIIYNTYGPTEATVATTLIEISDQHLHSDMELLPIGESRSGSTLTLEN---- 325
Query: 140 NTMGKIIL--ASKTRKCILLNRKNGNK---EENSIKFIDTGDIGEIRNGTVFYRGRVDDT 194
G+I++ A RK I ++ N+ ++ + TGDIG++ + + GR D+
Sbjct: 326 ---GEIVISGAHVMRKYIGAKTEDNNRLTINQHGTRSFRTGDIGKLIDNIWYCFGRKDNQ 382
Query: 195 IKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ----TPLLLIVYFSAETLSSQE-LLDFL 249
IK G++I LH IE +M P V S + L+ + + L+ + +T++++E L++ L
Sbjct: 383 IKLNGYRIELHEIEERLMNIPIVDSAVVLPLKKEDGSIVRLVAFCKFKTITNKENLVNLL 442
Query: 250 KCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
K L P + I +D P + K + L++IY +
Sbjct: 443 KNNLPSYMIPSEFINIDNFPVTNNSKIDTKSLLSIYNNN 481
>UniRef50_A1ZLW0 Cluster: Bacitracin synthetase 1 (BA1), putative;
n=1; Microscilla marina ATCC 23134|Rep: Bacitracin
synthetase 1 (BA1), putative - Microscilla marina ATCC
23134
Length = 1301
Score = 75.4 bits (177), Expect = 5e-12
Identities = 93/363 (25%), Positives = 162/363 (44%), Gaps = 37/363 (10%)
Query: 3 EILLACTNGASLLIAPDLT-EVLFHED--NDNSVTFWQTTPSKFFQHSNENIKNKILCAR 59
EI A T+GA+LL+ + + +VL +D ++ T TTP+ N+ L +
Sbjct: 651 EIYPALTSGATLLMVKEGSKDVLTIKDYIENHQATLLTTTPTIV------GWLNEELSST 704
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
L+ L GGE L +++ H K I YG +E + A+ N +T +
Sbjct: 705 QQLRWLISGGELLKP----EQIDHLFGKVNIANGYGPSETTVAAT-----FNIITNQTQA 755
Query: 120 VPLGNCLSETELFVQPHEKNN-----TMGKIILASKTRKCILLNRKNGNKE---ENSI-- 169
+G ++ +++ +EKN +G+I + LNR +E EN
Sbjct: 756 SLIGKPVANKPIYIV-NEKNQLQPVGVVGEICIGGTGLAQKYLNRPKLTRENFPENPFAE 814
Query: 170 --KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+G + NG + + GR D+ +K G++I L IE+ + Q ++ + +
Sbjct: 815 GERIYKTGDLGRWLPNGNIEFLGRKDEQVKIRGYRIELSEIENVLRQSGLIKDGVLLVKK 874
Query: 227 ----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
L+ V E +ELL + K L P V+ + LP N HGK K+ L
Sbjct: 875 HKNNKQLVAYVVPQQEQFEQEELLAYAKEWLPHYMIPSLVVPMGELPMNTHGKLDKKALP 934
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLS 341
+S+ Q + + + + A+ ++ L E + +FF LGG S LAV + K++
Sbjct: 935 KADFRSSDRQAYVAPTTSIEQNIAAIWHELLGVEKIGVHDNFFELGGQSILAVRLIAKIN 994
Query: 342 LTF 344
++
Sbjct: 995 ASY 997
>UniRef50_A0UXC9 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain - Clostridium
cellulolyticum H10
Length = 3695
Score = 74.9 bits (176), Expect = 7e-12
Identities = 91/370 (24%), Positives = 168/370 (45%), Gaps = 33/370 (8%)
Query: 3 EILLACTNGASLLIAPDLTEV---LFHEDND-NSVTFWQTTPSKFFQ-----HSNENIKN 53
EI + +G L I PD LF E D VT W + P+ Q S + + N
Sbjct: 3264 EIFGSLLSGTCLCIVPDSRMKDGSLFMEYIDAGKVTIWHSVPALMIQLLTAVKSRKTLGN 3323
Query: 54 KILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKV 113
+ L +R ++ + +GGE ++ K+++ + RI +YG TE + W V D+
Sbjct: 3324 QELFSR--IRCIMIGGEAWT-YELAKDIREYFHHARIVNMYGPTEATIW--VTSHDVRDN 3378
Query: 114 TTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILA--SKTRKCILLNRKNGNK--- 164
+P+G +S ++ + K G I ++ + TR K
Sbjct: 3379 PGSSTVIPIGKPISNNKVLILDSCKKMCPIGIPGDIYISGLNVTRGYYKDEEKTREVFTL 3438
Query: 165 --EENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
E+ SI + TGD+G + +GT+ Y GR D IK G++I + IE+ ++Q + +
Sbjct: 3439 YGEKGSIIY-RTGDVGRYLSDGTIEYLGRKDGMIKVRGYRIEIGEIENVLLQNEEIIQAA 3497
Query: 222 CVWL---QTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
V +T L+ Y + + +EL L+ KL + P + I ++ + +GK +
Sbjct: 3498 VVAKKSGETSKLICYYTAPREHTYEELRGCLEKKLPDYMIPAQFIWLEKMILTPNGKIDR 3557
Query: 279 EIL--VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVT 335
+ L ++I + +N +S + + L + ++ L+ + + +K +FFSLGG S L
Sbjct: 3558 KSLAALDIGEPFQSNENYAVPESEVERFLAGIWSQLLDMKKVGTKDNFFSLGGNSLLVNQ 3617
Query: 336 ICNKLSLTFP 345
+ + + +P
Sbjct: 3618 MHSMIDEKYP 3627
Score = 65.3 bits (152), Expect = 6e-09
Identities = 83/339 (24%), Positives = 151/339 (44%), Gaps = 33/339 (9%)
Query: 31 NSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRI 90
NS+ Q TPS+ +++ L S +VL +GGE +L E+K N RI
Sbjct: 2239 NSIEMLQMTPSRLQLLLSDSRGRSSL---SVPQVLMVGGEAFPQA-LLDEVKRCTN-ARI 2293
Query: 91 FTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKII 146
+ +YG TE + W+++ EL T + +G ++ T++++ N G++
Sbjct: 2294 YNMYGPTETTIWSTIREL------TDRSTIDIGKPIANTQVYIVSESGNLQPIGIPGELC 2347
Query: 147 LASKTRKCILLNRKNGNKE---ENSI----KFIDTGD-IGEIRNGTVFYRGRVDDTIKRF 198
++ +NR E EN K TGD + + +G + Y R+D +K
Sbjct: 2348 ISGDGLSRGYINRPELTLEKFLENPYMPGKKMYRTGDFVKWLPDGNIEYIRRIDHQVKLR 2407
Query: 199 GHKINLHSIESTVMQCPRVRSCSCVWL---QTPLLLIVYFSAE-TLSSQELLDFLKCKLD 254
G++I L IE +++ VR L Y +A+ L+ EL +L+ +L
Sbjct: 2408 GYRIELGEIEELLLKYSGVREAVVDVKGEDSESRKLGAYVTADRDLTEVELKKYLENELP 2467
Query: 255 EKYWPDKVIRVDTLPTNAHGKTSKEIL-VNIYKKSNILQNVENIKSYLFKELKALVNKDL 313
+ P ++ ++ LP +GKT ++ L + N V+ + K L+ + L
Sbjct: 2468 QYMIPTYIMVLEELPLTPNGKTDRKALPCPVLTGLNTNGFVDAVNE-TEKALQRIYQDVL 2526
Query: 314 NYEDL-QSKSFFSLGGTSFLAVTICNKLSLTFPEVGKHI 351
N + + +FF+LGG S A + +++ + E+G I
Sbjct: 2527 NIQRAGVNDNFFALGGHSLKATILVSRI---YKELGTEI 2562
>UniRef50_Q2VQ15 Cluster: Nonribosomal peptide synthetase C; n=3;
Brevibacillus texasporus|Rep: Nonribosomal peptide
synthetase C - Brevibacillus texasporus
Length = 4617
Score = 74.5 bits (175), Expect = 9e-12
Identities = 78/300 (26%), Positives = 134/300 (44%), Gaps = 25/300 (8%)
Query: 55 ILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVT 114
I C +S KVL GGE + +LK L + R+ +YG TE + +A+ +D + +T
Sbjct: 715 ITCFQSIRKVL-FGGELASVKHVLKALDYLGEH-RVINVYGPTETTVYATYYSVDHSMLT 772
Query: 115 TGDKEVPLGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKE---E 166
VP+G ++ T+ ++ QP + +G++ + + C LNR K+ +
Sbjct: 773 RAS--VPIGRPINNTKAYIVNTDGQP-QPIGVVGELCIGGEGVACGYLNRPELTKKHFVD 829
Query: 167 NSI----KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
N + TGD+ + +G + Y GR+D+ +K GH+I L IE ++Q P +
Sbjct: 830 NPFVLGERMYCTGDLARFLPDGNIEYIGRMDEQVKIRGHRIELGEIEKVLLQHPAISETV 889
Query: 222 CVWL---QTPLLLIVYFSAETL-SSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ Q L Y + + EL L L E P I ++ LP A+GK
Sbjct: 890 LLAKRDEQGHSYLCAYIVGQVFWTVTELRQHLMESLPEYMVPSYFIEIEKLPLTANGKVD 949
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTI 336
K L +K ++ ++L + L E + ++ +FF LGG S A+ +
Sbjct: 950 KRALPEPDRKMGSAYVAPENETE--EKLVQFFQEILGVERVGTQDTFFELGGHSLKAMML 1007
Score = 59.7 bits (138), Expect = 3e-07
Identities = 85/359 (23%), Positives = 158/359 (44%), Gaps = 29/359 (8%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHS--NENIKNKILCARS 60
+I A NGA+L++ P EV+ + + Q F S + ++ + +S
Sbjct: 2733 DIYSALLNGATLVLVPK--EVMLNPMELAKIVREQDITVSFMTTSLFHTLVELDVTSMKS 2790
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
KV+ GGE + + K L + + R+ YG TE + +A+ +D + TG V
Sbjct: 2791 MRKVV-FGGEKASYKHVEKALDYLG-EGRLVNGYGPTETTVFATTYTVDSSIKETGI--V 2846
Query: 121 PLGNCLSETELFVQPHEKNNTM-----GKIILASKTRKCILLNRKNGNKE---ENSI--- 169
P+G L+ T ++V +E N G++ + LNR E EN
Sbjct: 2847 PIGRPLNNTSVYVL-NENNQLQPIGVPGELCVGGAGIARGYLNRPELTAERFVENPFVSG 2905
Query: 170 -KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT 227
+ TGD+ + +G++ Y GR+D+ +K G++I L IE+ +++ P + + + Q
Sbjct: 2906 DRMYRTGDLARWLPDGSMEYLGRMDEQVKVRGYRIELGEIETRLLEHPSISAAVLLAKQD 2965
Query: 228 P---LLLIVYFSAETL-SSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L Y A + + EL L L E P + ++ +P ++GK +K L
Sbjct: 2966 EQGHSYLCAYIVANGVWTVAELRKHLSEALPEYMVPTYFVELEQIPFTSNGKVNKRALPE 3025
Query: 284 IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKS-FFSLGGTSFLAVTICNKLS 341
+ + ++ ++ AL + L E + ++ FF LGG S A+ + +++
Sbjct: 3026 PEGQMTSVYVAPETETE--AKVAALFQEILGVERVGTQDMFFELGGHSLKAMMLVLRMN 3082
Score = 56.8 bits (131), Expect = 2e-06
Identities = 84/360 (23%), Positives = 156/360 (43%), Gaps = 33/360 (9%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHS--NENIKNKILCARS 60
+I A NGA+L++ P EV+ + + Q F S + ++ + +S
Sbjct: 1698 DIYSALLNGATLVLVPK--EVMLNPMELARIVREQDITVSFMTTSLFHTLVELDVTSMKS 1755
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
KV+ GGE + + K L + + R+ YG TE + +A+ +D + TG V
Sbjct: 1756 IRKVV-FGGEKASYKHVEKALDYLG-EGRLVNGYGPTETTVFATTYTVDSSIKETGI--V 1811
Query: 121 PLGNCLSETELFVQPHEKNNTM-----GKIILASKTRKCILLNRKNGNKE---ENSIKFI 172
P+G L+ T +++ +E N G++ + LNR E +N
Sbjct: 1812 PIGRPLNNTSVYIL-NENNQPQPIGVPGELCVGGAGIARGYLNRPELTAERFVDNPFLVG 1870
Query: 173 D----TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL-- 225
D TGD+ + +G + Y GR+D+ +K GH+I L IE ++++ P + V
Sbjct: 1871 DRMYRTGDMARFLPDGNIEYIGRMDEQVKIRGHRIELGEIEKSLLEYPAISEAVLVAKRD 1930
Query: 226 -QTPLLLIVY-FSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
Q L Y S + + ++ + L E P + ++ LP ++GK K L
Sbjct: 1931 EQGHSYLCAYVVSTDQWTVAKVRQHILEALPEYMVPSYFVELEKLPLTSNGKVDKRALPE 1990
Query: 284 IYK--KSNILQNVENIKSYLFKELKALVNKD-LNYEDLQSKSFFSLGGTSFLAVTICNKL 340
+ + + V + L + + ++ D + +D +FF LGG S A+ + +++
Sbjct: 1991 PDRVITNEYVAAVNETEEKLVQFFQEILAVDRVGTQD----TFFELGGHSLKAMMLVSRI 2046
Score = 45.2 bits (102), Expect = 0.007
Identities = 48/175 (27%), Positives = 78/175 (44%), Gaps = 10/175 (5%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL---QTPL 229
TGD+ + +G + + GR+DD +K GH+I L IE+ +++ +V + Q
Sbjct: 3937 TGDLVRWLPDGNIEFLGRIDDQVKIRGHRIELGEIETRLLEHEQVIEAVVLAREDEQGQA 3996
Query: 230 LLIVYF-SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L Y +A+ + EL L L + P I ++ P GK +K+ L
Sbjct: 3997 YLCAYLVAADEWTVAELRKHLGKTLPDYMIPAYFIELEEFPLTPSGKVNKKALPE--PDG 4054
Query: 289 NILQNVENIKSYL--FKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
I VE +++ K L L + L E + +FF LGG S A+ I +L
Sbjct: 4055 QIQTGVEYVEATTESQKILVELWQEVLRVERIGIYDNFFELGGDSIKAIQITARL 4109
>UniRef50_Q84BC8 Cluster: NcpA; n=5; Cyanobacteria|Rep: NcpA - Nostoc
sp. ATCC 53789
Length = 3735
Score = 74.1 bits (174), Expect = 1e-11
Identities = 96/372 (25%), Positives = 170/372 (45%), Gaps = 49/372 (13%)
Query: 2 VEILLACTNGASLLIAPDLTEVLFHEDND----NSVTFWQTTPSKFFQHSNENIKNKILC 57
+EI L T GA L+IA + E D + T Q TP+ + + N +
Sbjct: 1791 LEIFLPITVGACLVIARRDVTLDGRELCDLLVKSKATIMQATPATWRLLLDSNYQF---- 1846
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
S LK+L GGE L + K L + ++ LYG TE + W+S+ +L+ + +
Sbjct: 1847 --SDLKILC-GGEALPWDLVSKLLARSAS---LWNLYGPTEATIWSSICQLE-----SSE 1895
Query: 118 KEVPLGNCLSETELFV-----QP---------HEKNNTMGKIILASK--TRKCILLN--R 159
+ +G +S T++++ QP H + + L T++ + N
Sbjct: 1896 SLISIGRPISNTQIYILDQNLQPVPIGVPGELHIGGAGLARGYLKRPELTQEKFIPNPFE 1955
Query: 160 KNGNK--EENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPR 216
+ G + E + TGD+ + +G + Y GR+D+ +K G +I L IE+ + Q P
Sbjct: 1956 EAGGRGQEAGGSRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQHPH 2015
Query: 217 VR-SCSCVWLQTP--LLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPT 270
V+ SC TP L+ Y + TL+ EL LK KL + P ++ +++LP
Sbjct: 2016 VQASCVIAREDTPGDKRLVAYIVPQPQVTLTISELRSNLKEKLPDYMVPSAIVILESLPL 2075
Query: 271 NAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSK--SFFSLGG 328
+GK + L S +L+ ++ + +E+ +L+ + + DL + +FF LGG
Sbjct: 2076 TPNGKIDRRALPAPEPSSELLEKYVAPRNPI-EEILSLIWQQVLKVDLVGRHDNFFELGG 2134
Query: 329 TSFLAVTICNKL 340
S LA + +++
Sbjct: 2135 HSLLATQLISRV 2146
Score = 64.9 bits (151), Expect = 8e-09
Identities = 76/311 (24%), Positives = 142/311 (45%), Gaps = 43/311 (13%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
TL+ + + GE ++++++ N F YG TE S A++A K T D+++
Sbjct: 785 TLQAIVVAGEACP-LELMRQWSKGRN---FFNAYGPTEASVCAAIA-----KCTPEDEKI 835
Query: 121 PLGNCLSETELFVQPHEKN----NTMGKIILASK------------TRKCILLN---RKN 161
+G ++ E+++ + G++ + T++ + N R
Sbjct: 836 TIGRPIANAEIYILDSQLQPVPIGVPGELHIGGAGVARGYLNRNELTQQKFIPNPFSRSR 895
Query: 162 GNKEENSI---KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV 217
G E+ S + TGD+ + +G + Y GR+D+ +K G +I L IE+T+ Q P V
Sbjct: 896 GAGEQGSRGRERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEATLSQHPHV 955
Query: 218 RSCSCVWLQTPL----LLIVYF---SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPT 270
++ SCV + + LI Y +T + +EL FLK KL E P + +++LP
Sbjct: 956 QA-SCVIAREDIPGDKRLIAYIVLQPEQTATVKELRSFLKEKLPEYMVPSAIAILESLPL 1014
Query: 271 NAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGT 329
+GK + L S + + ++ + + L + + L E + + +FF LGG
Sbjct: 1015 TPNGKIDRRALPE--PTSELSEKYVAPRTPIEEILAVIWQQVLKLELVGRHDNFFELGGH 1072
Query: 330 SFLAVTICNKL 340
S LA +++
Sbjct: 1073 SLLATQFISRV 1083
Score = 59.3 bits (137), Expect = 4e-07
Identities = 46/175 (26%), Positives = 89/175 (50%), Gaps = 10/175 (5%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--- 229
TGD+ + +G + Y GR+D+ +K G +I L IE+ + Q V++ S V ++ +
Sbjct: 3055 TGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQHSDVQT-SVVIVREDIPGN 3113
Query: 230 -LLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
L+ Y + T + +L FLK KL E P ++ +++LP +GK + L
Sbjct: 3114 KRLVAYVVPQPQITPTVSQLRSFLKEKLPEYMVPSAIVTLESLPLTPNGKIDRRALPEPE 3173
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNK 339
++ I ++ ++ + ++L + + L E + +FF LGG S L++ I ++
Sbjct: 3174 ARTGIESSLVAPRTPIEEKLTRIWEQVLRVEQIGIHDNFFELGGDSILSIQIISR 3228
>UniRef50_A3INW7 Cluster: Amino acid adenylation; n=1; Cyanothece sp.
CCY 0110|Rep: Amino acid adenylation - Cyanothece sp. CCY
0110
Length = 1438
Score = 74.1 bits (174), Expect = 1e-11
Identities = 82/350 (23%), Positives = 153/350 (43%), Gaps = 32/350 (9%)
Query: 65 LALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGN 124
L LGGE ++ +++ K R+F YG TE + + ++ T G VP+G
Sbjct: 710 LILGGEAAPW-GLIDQIRQKAPNCRLFNHYGPTETTVGVTTFPIEFQTPTVGT--VPIGR 766
Query: 125 CLSETELFV-QPHEKNNTMG---KIILASKTRKCILLNRKN-------GNKEENSIKFID 173
+ T+L++ P+ K MG ++ + LNR N +
Sbjct: 767 PIDNTQLYILDPYLKPVPMGVTGELYIGGAGVARGYLNRPELTAQRFISNPFNPQERLYK 826
Query: 174 TGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLLLI 232
TGD + + +G + + R+D+ +K G +I L IE+T+++ P + + + L+
Sbjct: 827 TGDNVRYLADGNIEFLDRLDNQVKIHGFRIELGEIEATLLENPHIFQAVVIAKEEHLIAY 886
Query: 233 VYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQ 292
+ T + +FL+ KL + P +++ LP +GK + L + I
Sbjct: 887 IVAEKNTSEPDQWREFLQRKLPDYMIPSSYVQLKALPLTKNGKIDRHKLPD----PQIQN 942
Query: 293 NVENI--KSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTFPEVGK 349
VE + ++ + +L + + L E + +FF+LGG S A+ + +K+S+
Sbjct: 943 TVEFVAPRNEIEAQLCEIWAEVLGVESIGIDDNFFTLGGHSLQAIQLVSKISMVM----- 997
Query: 350 HILPHLLSHNKSIGDVLKTITQDTNCLENKFKKSIKRNRSTSSHGENSIS 399
+ KS+ + T+ + + LENK K S N+ T S E +S
Sbjct: 998 ----NCDISVKSL-FLRPTVAKFSPILENKSKPSQPMNQVTQSKPEVQLS 1042
>UniRef50_Q8TPZ1 Cluster: Cell surface protein; n=1; Methanosarcina
acetivorans|Rep: Cell surface protein - Methanosarcina
acetivorans
Length = 3988
Score = 74.1 bits (174), Expect = 1e-11
Identities = 74/338 (21%), Positives = 150/338 (44%), Gaps = 26/338 (7%)
Query: 419 WTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCV 478
WT+ TG + +SPA+ ++ +V +GS+ GK+ N + G ++ ++I
Sbjct: 146 WTYVTGNSIRSSPAIGENRTVY---IGSYDGKLYAFNPD-GTLKWSYTTGNQITGSATIG 201
Query: 479 HDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCK-GVLYIASYDGNI 537
D + C +G+YD + + + ++ W G+ I S A + G +Y+ S D +
Sbjct: 202 ADGTI---C--IGSYDRRLYT-INPDGTLKWSYTTGNQIFSSAAIGEDGTIYVGSRDNKL 255
Query: 538 RCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKG 597
++ T+K + +Q S+ + ++ I G+L L+ + T+ W +
Sbjct: 256 YALN-PDGTLKWSYTTGNQIFSS-AAIGEDGTIYIGSLDKKLHALNPD-GTLKWSYTTGN 312
Query: 598 PIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQ 657
I+ P + +D + ++ ++H + +K W+Y A I+ S +
Sbjct: 313 QIYGSPAI-GSDGTIYIGSLDSKLHALNPDGTLK-WSYT-AGNQIYGSPAIGS----DGT 365
Query: 658 MYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSEL 717
+Y G D+ +Y++N +L W V + + + + +D I S D K++ I +
Sbjct: 366 IYIGSLDSKLYALNPDG---TLKWSCTVGNQILGSAALGSDGTIYIGSYDSKIYAITPD- 421
Query: 718 GTVTAQYQLPGETFSSPII-CDDHVFIGCRNDLLYSLK 754
GT+ Y + SP I D ++IG + LY+ +
Sbjct: 422 GTLKWSYATGNRIYGSPAIGSDGTLYIGSFDSSLYAFR 459
Score = 59.7 bits (138), Expect = 3e-07
Identities = 57/269 (21%), Positives = 117/269 (43%), Gaps = 17/269 (6%)
Query: 490 VGTYDGTVICFLLENCSVIWQINVGSMIKSKATY-CKGVLYIASYDGNIRCIDILTSTIK 548
+G+YDG + F + ++ W G+ I AT G + I SYD + I+ T+K
Sbjct: 168 IGSYDGKLYAFNPDG-TLKWSYTTGNQITGSATIGADGTICIGSYDRRLYTINP-DGTLK 225
Query: 549 ETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDN 608
+ +Q S+ + ++ I G+ L+ + T+ W + IF+ + +
Sbjct: 226 WSYTTGNQIFSS-AAIGEDGTIYVGSRDNKLYALNPDG-TLKWSYTTGNQIFSSAAIGE- 282
Query: 609 DKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVY 668
D + ++ ++H + +K W+Y I+ S + +Y G D+ ++
Sbjct: 283 DGTIYIGSLDKKLHALNPDGTLK-WSYTTGN-QIYGSPAIGSDGT----IYIGSLDSKLH 336
Query: 669 SVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPG 728
++N +L W + +Y +P I +D I S D KL+ ++ + GT+ +
Sbjct: 337 ALNPDG---TLKWSYTAGNQIYGSPAIGSDGTIYIGSLDSKLYALNPD-GTLKWSCTVGN 392
Query: 729 ETFSSPII-CDDHVFIGCRNDLLYSLKID 756
+ S + D ++IG + +Y++ D
Sbjct: 393 QILGSAALGSDGTIYIGSYDSKIYAITPD 421
Score = 47.6 bits (108), Expect = 0.001
Identities = 61/325 (18%), Positives = 132/325 (40%), Gaps = 24/325 (7%)
Query: 388 RSTSSHGENSISYKKGAGGIRNSNTVEFVVQWTFDTGKCVDASPALYKSESVLYVTVGSH 447
RS+ + GEN Y G + + ++W++ TG + S + + + +GS+
Sbjct: 155 RSSPAIGENRTVYIGSYDGKLYAFNPDGTLKWSYTTGNQITGSATIGADGT---ICIGSY 211
Query: 448 SGKIVVMNANTGFIQGLIKLKSRIEAPILCVHDECVTSPCGVVGTYDGTVICFLLENCSV 507
++ +N + G ++ ++I + D + VG+ D + L + ++
Sbjct: 212 DRRLYTINPD-GTLKWSYTTGNQIFSSAAIGEDGTI-----YVGSRDNKLYA-LNPDGTL 264
Query: 508 IWQINVGSMIKSKATYCK-GVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAK 566
W G+ I S A + G +YI S D + ++ T+K + +Q I +
Sbjct: 265 KWSYTTGNQIFSSAAIGEDGTIYIGSLDKKLHALN-PDGTLKWSYTTGNQ-IYGSPAIGS 322
Query: 567 NEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTV 626
+ I G+L L+ + T+ W + I+ P + +D + ++ +++
Sbjct: 323 DGTIYIGSLDSKLHALNPD-GTLKWSYTAGNQIYGSPAI-GSDGTIYIGSLDSKLYALNP 380
Query: 627 EKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVS 686
+ +K W+ I S + +Y G +D+ +Y++ +L W
Sbjct: 381 DGTLK-WSCT-VGNQILGSAALGS----DGTIYIGSYDSKIYAITPDG---TLKWSYATG 431
Query: 687 SPVYSTPTIFNDKLILAASTDGKLW 711
+ +Y +P I +D + S D L+
Sbjct: 432 NRIYGSPAIGSDGTLYIGSFDSSLY 456
>UniRef50_A0ZL89 Cluster: Non-ribosomal peptide synthase; n=1;
Nodularia spumigena CCY 9414|Rep: Non-ribosomal peptide
synthase - Nodularia spumigena CCY 9414
Length = 1490
Score = 73.7 bits (173), Expect = 2e-11
Identities = 72/324 (22%), Positives = 143/324 (44%), Gaps = 20/324 (6%)
Query: 40 PSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEM 99
P+ ++Q ++ K + +L+++ G E + K+L K K + YG TE
Sbjct: 740 PAPYWQEWVLELERKSIQIPDSLRLVVTGSEQVLAEKLLLWQKLVGEKVQWVNAYGPTEA 799
Query: 100 SCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCI 155
+ A++ +L N +G V +G+ ++ TE+++ G++ +
Sbjct: 800 TITATIYQLTANSQLSGINSVSIGSPIANTEIYILDQNLQPVPIGVFGELHIGGAGLARG 859
Query: 156 LLNRKNGNKEE---------NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLH 205
LNR E+ S + TGD+ + +G + + GR+D +K G +I L
Sbjct: 860 YLNRPELTHEKFISNLIPTAKSSRLYKTGDLARYLPDGNIEFLGRIDYQVKIRGFRIELG 919
Query: 206 SIESTVMQCPRVRSCSCVWLQTPL---LLIVYF-SAETLSSQ-ELLDFLKCKLDEKYWPD 260
IE+ + Q P V++ + + + L ++ Y + E Q FL+ KL + P
Sbjct: 920 EIEAVLAQHPLVKTSAVIVREIQLGSKQIVAYVVTQEDADIQTNFRSFLQEKLPDYMIPA 979
Query: 261 KVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ- 319
+R+ LP GK ++ L ++ + N N ++ L +++ + + L E +
Sbjct: 980 FFVRLAELPLTTTGKINRPALSALHLELNHETNYILPRNPLEQQIAEIWCQVLGLEKISI 1039
Query: 320 SKSFFSLGGTSFLAVTICNKLSLT 343
++FF LGG S + + ++L T
Sbjct: 1040 DENFFELGGHSLATMQVISRLQET 1063
>UniRef50_UPI000045BE69 Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide
synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 1401
Score = 72.9 bits (171), Expect = 3e-11
Identities = 77/339 (22%), Positives = 156/339 (46%), Gaps = 36/339 (10%)
Query: 33 VTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFT 92
VT W + P+ + E ++ S+++++ + G+ + + + +++ N ++ +
Sbjct: 775 VTVWNSAPA-LMKLLVEYAGDRCDRLSSSIRLVMMSGDWIP-VTLPEQIHSLGNDVQVIS 832
Query: 93 LYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFV-----QPHEKNNTMGKIIL 147
L G TE S W+ ++ V +P G LS + + QP + G+I +
Sbjct: 833 LGGATEASIWSIFYPIEA--VDPSWTSIPYGKPLSNQSIHILDEALQPRP-DWVPGQIYI 889
Query: 148 ------------ASKTRKCILLNRKNGNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDT 194
A+KT+ + + + G + TGD+G + +G + + GR+D
Sbjct: 890 GGVGLAQGYWRDAAKTQASFIQHPRTGER------LYCTGDLGRYLPDGNIEFLGRIDFQ 943
Query: 195 IKRFGHKINLHSIESTVMQCPRVRSC--SCVWLQTP----LLLIVYFSAETLSSQELLDF 248
+K G++I + IE+ + Q P +RS S V Q + IV+ ++++S EL +
Sbjct: 944 VKIRGYRIEIGEIETVLQQHPAIRSVAVSAVGEQRDDKQLVAYIVFEQEQSITSLELRSY 1003
Query: 249 LKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKAL 308
L+ KL E P + +D+LP +++GK + L + L+ + + L +L +
Sbjct: 1004 LQQKLPEYMIPSMFMFMDSLPLSSNGKVDRRALPDPEPSQADLEAIVAPRDSLELQLVQI 1063
Query: 309 VNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTFPE 346
+ L ++ + +FF LGGTS AV + ++ F +
Sbjct: 1064 WQEILKLPEVGITNNFFELGGTSIQAVRLMTQIHKLFAQ 1102
>UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2;
Cyanobacteria|Rep: Amino acid adenylation - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 2791
Score = 72.9 bits (171), Expect = 3e-11
Identities = 66/271 (24%), Positives = 123/271 (45%), Gaps = 27/271 (9%)
Query: 31 NSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRI 90
+ +T W + PS + K +++ +L+ + + GE + I+++K + T +
Sbjct: 2488 HQITHWLSVPSLYNSLLAHIEKQQLI----SLQTIIVAGETCS-IELVKNHQKLLPNTSL 2542
Query: 91 FTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFV-QPHEKN---NTMGKII 146
F YG TE + W+SV + + + +P+G +S T++++ H + T G+I
Sbjct: 2543 FNEYGPTETTVWSSVYNCSHHDLN--NNSIPIGRPISNTQIYILNSHLQPVPIGTPGEIY 2600
Query: 147 LASKTRKCILLNRKNGNKE---------ENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIK 196
+ LNR E + + + TGD + NG + + GR+D IK
Sbjct: 2601 IGGFGVSKGYLNRPELTIEKFIPDPFSKQPNARLYKTGDQARYLSNGNIEFIGRIDHQIK 2660
Query: 197 RFGHKINLHSIESTVMQCPRVRSCSCVWL------QTPLLLIVYFSAETLSSQELLDFLK 250
G++I L IE+ + Q P+V+ + Q + IV + + EL FL+
Sbjct: 2661 LRGYRIELGEIEAVLQQHPQVKQAIVIARNSDSENQQLVAYIVPSQTQDSLTNELRSFLQ 2720
Query: 251 CKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
KL P ++++DTLP +GK ++ L
Sbjct: 2721 TKLPNYMIPSVILQIDTLPLTPNGKIDRQKL 2751
Score = 44.0 bits (99), Expect = 0.015
Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLL-- 230
TGD+ +G++ Y GR+DD +K G +I L IES + Q P VR V +T +
Sbjct: 1530 TGDLARYHTDGSIEYLGRLDDQVKLRGFRIELTEIESVLTQHPDVRKAVVVMRETSAVKR 1589
Query: 231 LIVYFSAETLSS-QELLDFLKCKLDEK 256
+V E S +L +FLK +L E+
Sbjct: 1590 QVVLNPPENNSEITDLRNFLKGELTEE 1616
Score = 35.5 bits (78), Expect = 5.4
Identities = 18/50 (36%), Positives = 27/50 (54%)
Query: 164 KEENSIKFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQ 213
K+ F+ TGD+G +++G +F GR+ D I G IE+TV Q
Sbjct: 431 KDTKEGPFLRTGDLGFLQDGELFITGRLKDLIIIRGRNYYPQDIENTVQQ 480
>UniRef50_Q7N7D9 Cluster: Similarities with lichenysin synthetase B;
n=1; Photorhabdus luminescens subsp. laumondii|Rep:
Similarities with lichenysin synthetase B - Photorhabdus
luminescens subsp. laumondii
Length = 594
Score = 72.5 bits (170), Expect = 4e-11
Identities = 76/337 (22%), Positives = 147/337 (43%), Gaps = 35/337 (10%)
Query: 32 SVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIF 91
S+ + TPS+ S E +++L KVL +GGE L + K L N RIF
Sbjct: 239 SIEMLKCTPSQLEMLSREGNLSELLPE----KVLIIGGEELTSA-LAKTLFAANPNLRIF 293
Query: 92 TLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIIL 147
YG +E + V LN G+ +P+G L+ E+ V + +G++ +
Sbjct: 294 NHYGPSETTI--GVLMHQLNGTRLGNDSIPIGKPLNGVEIAVLDDARRPVSPGEVGQLYI 351
Query: 148 ASKTRKCILLNRKNGNKEENSIKFID--------TGD-IGEIRNGTVFYRGRVDDTIKRF 198
+ L +G+++ F+D +GD + + G + GRVD +K
Sbjct: 352 GGRA----LARGYHGDQDLTETHFVDIFGRRFYASGDLVKQNEQGNYLFIGRVDRQLKIR 407
Query: 199 GHKINLHSIESTVMQCPRVRSCSCVWLQTPLLLI---VYFSAETLSSQELLDFLKCKLDE 255
G++I IE+ ++ P ++ +++ I V + T ELL L +L
Sbjct: 408 GYRIQPKEIENALLAEPGIKQVVVTSVKSEFHQIDELVAYVVGTARENELLSNLATRLPA 467
Query: 256 KYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALV----NK 311
+ P ++ +D + NA+GK + + N ++++ + + +++ L+ +
Sbjct: 468 SHIPSRIYNIDEILVNANGKLD---IARLQASVNTVESISSDVTVPCNDIEKLILDIWRE 524
Query: 312 DLNYEDLQSKS-FFSLGGTSFLAVTICNKLSLTFPEV 347
L +D+ ++ F GG SF ++ + +L FP +
Sbjct: 525 VLKRDDIDMQAKFLESGGDSFKSLVVFGRLRRHFPNL 561
>UniRef50_Q6D2G7 Cluster: Putative D-alanine--poly(Phosphoribitol)
ligase subunit 1; n=1; Pectobacterium atrosepticum|Rep:
Putative D-alanine--poly(Phosphoribitol) ligase subunit
1 - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 477
Score = 72.5 bits (170), Expect = 4e-11
Identities = 60/256 (23%), Positives = 118/256 (46%), Gaps = 9/256 (3%)
Query: 30 DNSVTFWQTTPSKFFQHS-NENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKT 88
DN V+ W +TPS +Q + ++ L L V GE LN ++K+L+ +
Sbjct: 220 DNGVSVWVSTPSFAYQKLLSPQFNSEYL---PELNVFVFIGEVLNKA-LVKQLRRRFPHA 275
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKNNTMGKIILA 148
+I YG TE + +V E+ + + + + +P+G + ++ + + + GK ++
Sbjct: 276 KILNSYGPTEATIATTVIEITDDILHSENDLLPVGAMMPDSRMEITAEGELIIWGKNVMR 335
Query: 149 SKTRKCILLNRKNGNKEENSIKFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIE 208
K ++E + + TGD+G NG ++ +GR D IK G++I ++ IE
Sbjct: 336 GYLGLAQENAEKLLHRESEAFRGYRTGDLG-YENGLLYCQGRNDSQIKLNGYRIEINEIE 394
Query: 209 STVMQCPRVRSCSCVWLQTP---LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRV 265
+ ++ + + L +L I F +L+ + + L + P ++I
Sbjct: 395 NRLLAISDISEAVVLPLMKSGGGVLRIAAFCVTSLAPEVIKTSLSKVIPPYMVPSQIIIK 454
Query: 266 DTLPTNAHGKTSKEIL 281
D LP N +GK +++L
Sbjct: 455 DALPLNPNGKIDRKLL 470
>UniRef50_A0UVH5 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain - Clostridium
cellulolyticum H10
Length = 2193
Score = 72.5 bits (170), Expect = 4e-11
Identities = 77/303 (25%), Positives = 131/303 (43%), Gaps = 22/303 (7%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S LK+ GE L I+++K K R+ +YG +E+S A+ + L T
Sbjct: 1839 SELKLWVTSGETLR-IELMKRFKQSIPNGRLINIYGSSEVSADATYYDTALASETLS--R 1895
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEENSIKFIDT- 174
VP+G + TE+++ K G++ +A LNR KE DT
Sbjct: 1896 VPIGRPIDNTEIYILDSNKQLVPIGVAGELYVAGDGLAKGYLNRPELTKERFVPNPYDTS 1955
Query: 175 ------GDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV---W 224
GD+ + +G + Y GR D+ +K G ++ IES +++ P V+ V
Sbjct: 1956 GLMYRMGDMARYLPDGNIEYLGRGDNQVKIRGIRVESGEIESVLLKFPSVKEAVVVSYGE 2015
Query: 225 LQTPLLLIVYF--SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
+ + L Y + EL F++ L E P + V+ +P +GK K+ L
Sbjct: 2016 AKGDVRLAAYIVPNVTVPEVDELRSFIRGYLSEYMIPASINFVEHMPLLPNGKIDKKSLP 2075
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLS 341
N L+ S + KE+ + N+ L ++ + SFF +GG S +A + +++
Sbjct: 2076 NPELLKGQLEFTPPC-SEIEKEIAQMWNEVLGVKESGINNSFFDMGGHSLMATQLISRIR 2134
Query: 342 LTF 344
L F
Sbjct: 2135 LKF 2137
Score = 68.5 bits (160), Expect = 6e-10
Identities = 76/303 (25%), Positives = 132/303 (43%), Gaps = 21/303 (6%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S LK+ GE L I+++K K R+ +YG +E+S A V D +
Sbjct: 779 SELKLWVTSGETLR-IELMKRFKQSIPNGRLINIYGSSEVS--ADVTYYDTALASETLSR 835
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEENSIKFIDT- 174
VP+G + TE+++ K G++ +A LNR +E DT
Sbjct: 836 VPIGRPIDNTEIYILDSNKQPVPIGVAGELYVAGDGLAKGYLNRPELTEERFVPNPYDTS 895
Query: 175 ------GDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV---W 224
GD+ + +G + Y GR D+ +K G ++ L IES +++ P V+ V
Sbjct: 896 GLMYRMGDMARYLPDGNIEYLGRGDNQVKIRGIRVELGEIESVLLKFPSVKEAVVVSYGE 955
Query: 225 LQTPLLLIVYFSAETLSSQ--ELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
L+ + L Y + + EL F++ L E P + V+ +P +GK K+ L
Sbjct: 956 LKGDVRLAAYIVPDVTVPEVDELRSFIRGYLPEYMIPVSINFVEHIPLLPNGKIDKKSLP 1015
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLS 341
+ + + ++ L + + +V+ LN E + +FF LGG S LA + +++
Sbjct: 1016 DPELFNFKEMSYIAPRNSLEEMVACIVSGVLNIEKVGIYDNFFDLGGHSLLATQVISRIR 1075
Query: 342 LTF 344
F
Sbjct: 1076 REF 1078
>UniRef50_Q7BQ71 Cluster: Peptide synthetase-like protein; n=1;
Bacillus cereus|Rep: Peptide synthetase-like protein -
Bacillus cereus
Length = 525
Score = 72.1 bits (169), Expect = 5e-11
Identities = 62/237 (26%), Positives = 112/237 (47%), Gaps = 18/237 (7%)
Query: 61 TLKVLALGGEPL--NGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
+LK + + GE L I +L + +N T + LYG TE + + + +++T G
Sbjct: 264 SLKQVFVSGEALLSQHINRFNKLLNFSNGTLLTNLYGPTEATIDVTAYDCPTHEITEGS- 322
Query: 119 EVPLGNCLSETELFVQPHEKNNT----MGKIILASKTRKCILLNRKNGNKEENSIKFIDT 174
VP+G + E+FV N +G++ ++ +NR E+ +DT
Sbjct: 323 -VPIGRPIKNIEMFVVDKYGNKLPEGHIGELCISGIGLARGYVNRPQLTAEKFVQYSLDT 381
Query: 175 -----GDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP 228
GD+ IR+ G + + GR+D +K G +I L IES +M C V C+ + Q
Sbjct: 382 RIYKTGDLALIRSDGNIEFHGRIDFQVKVNGLRIELGEIESCLMSCEGVLQCAVIVRQES 441
Query: 229 ---LLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
+ LI ++ +E + + L +L+ L + P+ +RV+ +P GK +++L
Sbjct: 442 EMVVKLIAFYESENDIELERLKKYLRLFLPDYMIPNSFVRVNEMPLTDSGKIDRKVL 498
>UniRef50_A5YBV1 Cluster: Fusaricidin synthetase; n=1; Paenibacillus
polymyxa|Rep: Fusaricidin synthetase - Paenibacillus
polymyxa (Bacillus polymyxa)
Length = 2564
Score = 72.1 bits (169), Expect = 5e-11
Identities = 69/299 (23%), Positives = 127/299 (42%), Gaps = 25/299 (8%)
Query: 3 EILLACTNGASLLIAPDLTE---VLFHED-NDNSVTFWQTTPSKFFQHSNENIKNKILCA 58
E+ A G L+I P LT F E DN VT TP+ F+Q E + +
Sbjct: 658 EMYGALLYGGKLVIVPSLTAKSPAAFLELLKDNQVTILNQTPTYFYQVLQEELMHS--ST 715
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
L+ + GGE L+ +L+ + K ++ +YG+TE + + E+ +++ G
Sbjct: 716 ELGLRKIIFGGEALSP-SLLRNWRVKYPDVQLINMYGITETTVHVTYKEITEHEIEAGKS 774
Query: 119 EVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEEN------- 167
+ G + ++ ++ G++ +A LNR + E+
Sbjct: 775 NI--GRTIPTLSAYILDEQRRLQPVGVPGELYIAGDGLARGYLNRPDLTSEKFVEHPYRV 832
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+ + +G + Y GR+D +K G++I L +E+ +++ P VR + +
Sbjct: 833 GERLYRTGDLARWLPDGNIEYLGRIDHQVKIRGYRIELGEVEAQILKAPSVRETIVLARE 892
Query: 227 ----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
LL Y ++ LS EL L +L P + ++ +P +GK + L
Sbjct: 893 DEQGQKLLCAYYVASSDLSPGELRAQLAAELPAYMIPSYFVPLEQMPLTPNGKLDRRAL 951
Score = 42.3 bits (95), Expect = 0.047
Identities = 40/173 (23%), Positives = 79/173 (45%), Gaps = 6/173 (3%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--- 229
TGD+ + +G + ++GR+D+ +K G++I L IE+ + + V V L
Sbjct: 1873 TGDLVRWLPDGNLEFKGRIDEQVKIRGYRIELPEIEAQLAKVESVIDAVVVVRADELGEK 1932
Query: 230 -LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L Y + TL++ E+ L L P I++D +P ++GK + L +
Sbjct: 1933 QLCAYYVADRTLTAGEVRLSLSQVLPGYMIPSYFIQMDRMPLTSNGKVDRRSLPAPQVGA 1992
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
+ + ++ + L ++ L + + +FF LGG S A+ + ++L
Sbjct: 1993 HTGRKYTAPRTPAEEALASVWQGVLGAKQVGIHDNFFELGGDSIKAIQVSSRL 2045
>UniRef50_A5FI50 Cluster: Amino acid adenylation domain; n=1;
Flavobacterium johnsoniae UW101|Rep: Amino acid
adenylation domain - Flavobacterium johnsoniae UW101
Length = 1568
Score = 72.1 bits (169), Expect = 5e-11
Identities = 87/359 (24%), Positives = 163/359 (45%), Gaps = 31/359 (8%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTL 62
E G +L I + ++ + + D +V T PS + +++KI + +
Sbjct: 724 EFFFTLAIGKTLRILKNALDIENYINTDQNVLL-NTVPSVV----RKLLEDKI--SLENI 776
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
KV+ + GE L I+ +L + + R LYG +E + + S + L ++K ++ + +
Sbjct: 777 KVINMAGEILP-TDIVDQLPIEKMEVR--NLYGPSEDTTY-STSHLVISKT---NRTISI 829
Query: 123 GNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKNGNKEE-------NSIKF 171
G +S T+ ++ GK+ L+ + LN+ E+ + +
Sbjct: 830 GRPMSNTQAWILNESLLPVPVGISGKLYLSGEGVTRGYLNKPELTAEKFVTNPFIENERM 889
Query: 172 IDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQ----CPRVRSCSCVWLQ 226
DTGD+ + +G + + GR D +K G +I L IE+ ++Q +V +
Sbjct: 890 YDTGDLAYWLPDGNIEFLGRKDHQVKIRGFRIELGEIEAALLQYSTDLKQVVAAVKEVNG 949
Query: 227 TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
+L Y S + L L FLK KL E P +R+++LP +GK +EIL I
Sbjct: 950 EKILAAYYISTKELDKSSLRAFLKDKLPEYMVPGFYVRLESLPLTPNGKIDREILPGING 1009
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
+ I + E K+ + K+L + + L+ +++ +FF LGG S A+ + +K+ F
Sbjct: 1010 EDLIRKEYEAPKNDIEKKLAEIWQEILSLKEVGIHDNFFELGGHSMKAMKLISKIKQEF 1068
>UniRef50_Q8YTR8 Cluster: Peptide synthetase; n=2; Nostocaceae|Rep:
Peptide synthetase - Anabaena sp. (strain PCC 7120)
Length = 2459
Score = 71.7 bits (168), Expect = 7e-11
Identities = 78/362 (21%), Positives = 163/362 (45%), Gaps = 33/362 (9%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTL 62
EI + G +++A + E L + VT T PS Q N N ++
Sbjct: 690 EIFVPLCWGGKVILAENALE-LPNLPAKYEVTLINTVPSAITQLLNFN------AIPHSV 742
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
+ L GEPL K++++L+ + I+ LYG +E + +++ EL +T P+
Sbjct: 743 NTVNLAGEPLTW-KLVQQLQQLPHVQHIYNLYGPSEDTTYSTYIEL--KDITPNSPTPPI 799
Query: 123 GNCLSETELFVQPHEKN----NTMGKIILASK------------TRKCILLNRKNGNKEE 166
G ++ T++++ G++ +A T + + + N ++
Sbjct: 800 GRAIANTQVYILDKHLQPVPVGVPGELYIAGAGVARGYWQRPELTAERFINQQSTVNSQQ 859
Query: 167 NSIKFI-DTGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW 224
+++ + TGD + + +G + Y GR+D+ +K G++I L I++ + Q P ++ +
Sbjct: 860 STVNTLYKTGDRVRYLPDGNIEYLGRLDNQVKIRGYRIELGEIDALLSQYPEIQESVVIA 919
Query: 225 LQT---PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
+T L+ Y + + ++ +L +L KL P + +D LP N +GK ++ L
Sbjct: 920 SETSSGDKNLVAYIAPKNINIADLRHYLTDKLPGYMIPAHFMTLDALPRNPNGKIDRKAL 979
Query: 282 VNIYKKSNILQ-NVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNK 339
+ S+ L ++ + L+ + + L E + +FF+LGG S L + + +
Sbjct: 980 PAVENLSSELGIGYVAPRTATEQALEVIWREILLVEPIGIYDNFFTLGGHSLLGMQLVAR 1039
Query: 340 LS 341
++
Sbjct: 1040 IN 1041
Score = 36.3 bits (80), Expect = 3.1
Identities = 36/119 (30%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 224 WLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
WL AE L +Q+L FL+ +L E P I ++TLP +GK + L
Sbjct: 2257 WLSPETAQTKVTKAE-LITQKLRQFLQQRLPEYMIPRLYIPLETLPLTPNGKIDRRALPQ 2315
Query: 284 -IYKKSNILQNVENIKSYLFKELKALVNKDLNYE-DLQSKSFFSLGGTSFLAVTICNKL 340
Y+ S Q + + L L L LN E +FF LGG S A I ++
Sbjct: 2316 PEYQFSQSEQPIIPPSTELEIALAQLWQSILNVEVSSIHNNFFELGGNSLSATQIITQM 2374
Score = 35.5 bits (78), Expect = 5.4
Identities = 24/108 (22%), Positives = 50/108 (46%), Gaps = 8/108 (7%)
Query: 29 NDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKT 88
N + VT W T P+ + + + TL+++ L G+ + + + ++ + N
Sbjct: 1795 NQHQVTIWNTVPALM-----QLLLDTSPTQNQTLRLILLSGDWIP-LTLPPRIRSQFNHP 1848
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPH 136
+I +L G TE S W+ ++ + K +P G L+ +++V H
Sbjct: 1849 QIISLGGATEASIWSIFYPIE--TIDPNWKSIPYGYSLTNQQVYVLNH 1894
>UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomonas
syringae pv. syringae|Rep: Amino acid adenylation -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 9498
Score = 71.7 bits (168), Expect = 7e-11
Identities = 92/367 (25%), Positives = 154/367 (41%), Gaps = 36/367 (9%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDN------DNSVTFWQTTPSKFFQHSNENIKNKIL 56
EI A G L+I P +EV D+ + VT TPS F Q ++
Sbjct: 7175 EIWGALCYGGKLVIVP--SEVARSPDDFYALVCEQQVTVLNQTPSAFRQFIQARERSP-- 7230
Query: 57 CARSTLKVLALGGEPLNGIKILKELKHKN--NKTRIFTLYGVTEMSCWASVAELDLNKVT 114
L+ + GGE L+ + L+ + ++TR+ +YG+TE++ A+ + +++
Sbjct: 7231 -QEHALREVVFGGEALD-FRSLQPWTARTPLSRTRLVNMYGITEITVHATYYPISQSEID 7288
Query: 115 TGDKEVPLGNCLSETELFV----QPHEKNNTMGKIILASKTRKCILLNRKNGNKE----- 165
T + +G L + L + Q G+I + LNR N E
Sbjct: 7289 TAMPSL-IGPALDDLCLRILDDYQQPVPVGVNGEIYIGGAGVARHYLNRTELNAERFIAD 7347
Query: 166 ----ENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSC 220
++ + TGD+ R +G V Y GR D IK G +I L IE+ ++ CP VR
Sbjct: 7348 PYALQSGARLYRTGDVAHYRSDGGVVYVGRNDSQIKIRGFRIELGEIEAQLLACPDVREA 7407
Query: 221 SCVWLQT---PLLLIVYFSAETLSSQE---LLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
+ + L+ Y AE ++ E L L L E P + ++T P +G
Sbjct: 7408 MVIVREDRPGDKRLVAYLIAEDGAAPESALLRSQLASVLAEHMLPSAFVTLETWPLTTNG 7467
Query: 275 KTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLA 333
K + L + + + ++ E + L A + L E + + FF LGG SFL
Sbjct: 7468 KLDRAALPAPDQFATVSRDYEAPLGAIETTLAAAWQELLGVERVGRQDHFFELGGHSFLV 7527
Query: 334 VTICNKL 340
+++ +L
Sbjct: 7528 ISLIERL 7534
Score = 56.0 bits (129), Expect = 4e-06
Identities = 68/302 (22%), Positives = 128/302 (42%), Gaps = 23/302 (7%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTE--MSCWASVAELDLNKVTTGDKE 119
++++ + G+ L+ K+ + + TR+ YG TE +SC A+ D + G
Sbjct: 2951 VRLINVTGDALSAQKLKLWDEVRPAHTRLINTYGPTEATVSCTAAYVSHDAAAGSEGSGN 3010
Query: 120 VPLGNCLSETELFV-QPHEKN---NTMGKIILASK--TRKCILLNRKNGNK-------EE 166
+G ++ T +++ H++ G+I + R + L N + E
Sbjct: 3011 ATIGKPMANTRIYLLDAHQQPVPYGVAGEIYIGGDGVARGYLNLEEVNAERFLADPFSES 3070
Query: 167 NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
+ TGD+ + +G + Y GR D +K G +I L IE+ + C V+ +
Sbjct: 3071 PDARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCTGVKEAVVIAR 3130
Query: 226 QT---PLLLIVYFSAET---LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
+ L+ Y A+ L++ +L L +L E P + +D LP + K ++
Sbjct: 3131 EDNPGDKRLVAYVVAQPQSQLTAADLRAELAPQLAEYMLPSAFVLLDELPLTPNRKLDRK 3190
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICN 338
L + I + E + ++ A+ L E + + FF LGG S LAV++
Sbjct: 3191 ALPAPDADALISRGYEAPQGETETQIVAIWQDLLGIEQVGRHDHFFELGGHSLLAVSLIE 3250
Query: 339 KL 340
+L
Sbjct: 3251 RL 3252
Score = 55.6 bits (128), Expect = 5e-06
Identities = 44/175 (25%), Positives = 81/175 (46%), Gaps = 8/175 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--- 229
TGD+G + +GT+ Y GR D +K G +I L IE+ ++ P +R +
Sbjct: 8448 TGDLGRWLADGTLEYMGRNDFQVKVRGFRIELGEIENVLLAVPGIREAIVIARNDSQGDS 8507
Query: 230 ---LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L+ Y E+++++ L L L E P +++D LP A+GK + L +
Sbjct: 8508 DSQRLVAYVCGESVAAEHLRSELLRHLPEYMVPSAFVQLDALPLTANGKLDRRALPAPGQ 8567
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + E + + + + L+ + + ++ F LGG S LAV + ++L
Sbjct: 8568 DALASKAYEAPQGETEEAIAEIWKALLHLDQVGRNDGFLELGGHSLLAVQLLSRL 8622
Score = 52.0 bits (119), Expect = 6e-05
Identities = 48/185 (25%), Positives = 87/185 (47%), Gaps = 9/185 (4%)
Query: 165 EENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
E+ + TGD+G + NG + Y GR D +K G +I + IE+ + + P V
Sbjct: 1981 EDRQARLYKTGDVGRWLANGALEYLGRNDFQVKIRGLRIEIGEIEAALAKHPAVHEAVVT 2040
Query: 224 W---LQTPLLLIVYF--SAE-TLSSQELL-DFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
+ L+ Y+ SAE T E+L L+ +L E P + ++ +P ++GK
Sbjct: 2041 AREDIPGDKRLVAYYTQSAEHTAVDLEILRSHLQQQLPEYMVPAIYVLLEAMPLTSNGKL 2100
Query: 277 SKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVT 335
++ L + I + E + + +++ + L E + + FF LGG S LAV+
Sbjct: 2101 DRKALPAPDGDALISRGYEAPQGEIEEQIAIIWQDLLGVEQVGRHDHFFELGGHSLLAVS 2160
Query: 336 ICNKL 340
+ ++L
Sbjct: 2161 LIDRL 2165
Score = 50.4 bits (115), Expect = 2e-04
Identities = 68/305 (22%), Positives = 129/305 (42%), Gaps = 29/305 (9%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTE--MSCWASVAELDLNKVTTGDKE 119
++++ + G+ L+ K+ + + TR+ YG TE +SC A+ D + G
Sbjct: 4038 VRLINVTGDALSAQKLKLWDEVRPAHTRLINTYGPTEATVSCTAAYVSYDAAAGSEGSGN 4097
Query: 120 VPLGNCLSETELFV-QPHEKN---NTMGKIILASK--TRKCILLNRKNGNK-------EE 166
+G ++ T +++ H++ G+I + R + L N + E
Sbjct: 4098 ATIGKPMANTRIYLLDAHQQPVPYGVAGEIYIGGDGVARGYLNLEEVNAERFLADPFSES 4157
Query: 167 NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
+ TGD+ + +G + Y GR D +K G +I L IE+ + C V+ +
Sbjct: 4158 PDARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCKGVKEAVVIAR 4217
Query: 226 QT---PLLLIVYFSAET---LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
+ L+ Y A+ +++ EL L +L E P + +D LP + K ++
Sbjct: 4218 EDNPGEKRLVAYVVAQPQTQITAAELRAELAPQLAEYMLPSAFVLLDELPLTPNRKLDRK 4277
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQS----KSFFSLGGTSFLAVT 335
L + + E+++ E+ AL N DL+ FF LGG S LA+
Sbjct: 4278 ALPA--PADDAFASREHVEPQGATEI-ALAQIWQNLLDLERVGRHDQFFELGGHSLLAMR 4334
Query: 336 ICNKL 340
+ +++
Sbjct: 4335 LISQV 4339
Score = 49.6 bits (113), Expect = 3e-04
Identities = 71/311 (22%), Positives = 131/311 (42%), Gaps = 37/311 (11%)
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
A + L+++ GGE + + +H + + R+F YG TE + A+ E+ V
Sbjct: 6161 ALAGLRMIMCGGERADPASFRRVREH-SAQVRLFNGYGPTEGTTCATSYEIF--DVLPDT 6217
Query: 118 KEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEENS----- 168
+P+G + ++V + +G+I + LNR E S
Sbjct: 6218 LSLPIGKPNANVRVYVLDARREPVPMGVVGEIYIGGTGVALGYLNRPELTAERFSEDPFS 6277
Query: 169 ----IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
+ TGD+ + +G + Y R D +K G ++ L IES + C VR+ V
Sbjct: 6278 QQAGARLYRTGDLARWLPDGNLEYLARNDGQVKVRGFRVELGEIESVLHLCDGVRNSVVV 6337
Query: 224 WLQTP---LLLIVYFSA----ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
+ L+ Y++ + ++L L L E P +R+D LP +GK
Sbjct: 6338 AHEASPGDTRLVAYYTVHAGVDAPDPEDLRAQLSADLAEYMVPSVFVRLDALPLTLNGKV 6397
Query: 277 SKEIL----VN-IYKKSNILQN--VENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGT 329
++ L +N +++++ + E + +F+EL L + + D FF LGG
Sbjct: 6398 DQKALPVPDLNAMFERTYVAPEGATEQALAEIFQELLGL--ERVGRHD----GFFELGGH 6451
Query: 330 SFLAVTICNKL 340
S LA + +++
Sbjct: 6452 SLLAAQLVSRV 6462
Score = 46.8 bits (106), Expect = 0.002
Identities = 49/188 (26%), Positives = 84/188 (44%), Gaps = 9/188 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW---LQTPL 229
TGD+G + NG + Y GR D +K G +I + IE+ + + P V +
Sbjct: 900 TGDVGRWLANGALEYLGRNDFQVKIRGLRIEIGEIEAALAKHPAVHEAVVTAREDIPGDK 959
Query: 230 LLIVYF--SAE-TLSSQELL-DFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
L+ Y+ SAE T E+L L+ +L E P + ++ +P ++GK ++ L
Sbjct: 960 RLVAYYTQSAEHTAVDLEILRSHLQQQLPEYMVPAIYVLLEAMPLTSNGKLDRKALPAPD 1019
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLSLTF 344
+ I + E + + L ++ L E + + FF LGG S LAV + ++
Sbjct: 1020 GDALISRGYEAPQGEVETLLASIWADVLKVEQVGRHDHFFELGGHSLLAVKLIERMRQVG 1079
Query: 345 PEVGKHIL 352
H+L
Sbjct: 1080 LSADVHVL 1087
Score = 41.1 bits (92), Expect = 0.11
Identities = 64/273 (23%), Positives = 110/273 (40%), Gaps = 28/273 (10%)
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGK 144
+I YGVTE S ++ E + G +P+G L+ T +++ G+
Sbjct: 5133 QIVQAYGVTEASIDSTCFEFEATSQVDG--VLPIGRALANTRIYLLDELGQAVPPGVAGE 5190
Query: 145 IIL--ASKTRKCILLNRKNGNK-EENSI----KFIDTGDIGEIR-NGTVFYRGRVDDTIK 196
+ + A R + L + + +N + +GD+ R +G + + GR D K
Sbjct: 5191 LYIGGAGIARGYLNLQQLTAERFMDNPFVAGERLYRSGDMARYRADGNIEFLGRNDSQAK 5250
Query: 197 RFGHKINLHSIESTVMQCPRVRSCSCVWLQ----TPLLLIVYF--------SAETLSSQE 244
G ++ L IE+ + + VR V + TP L I YF S L+ +
Sbjct: 5251 LRGLRLELGEIEARLAEVAGVRESLVVIREDSGGTPKL-IAYFVEYATRDESGPALTPRA 5309
Query: 245 LLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKE 304
L L+ L E P +R+ LP +A+GK + L + + E L
Sbjct: 5310 LRQQLQLNLPEYMIPAAFVRMAALPLSANGKLDRRALPEPDADAFDQHDFEAADGPLETA 5369
Query: 305 LKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTI 336
+ A+ L + + FF+LGG S L + +
Sbjct: 5370 IAAIWADVLGVAQVGRHDDFFALGGHSLLVMRV 5402
>UniRef50_A7D4L7 Cluster: Pyrrolo-quinoline quinone precursor; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep:
Pyrrolo-quinoline quinone precursor - Halorubrum
lacusprofundi ATCC 49239
Length = 445
Score = 71.7 bits (168), Expect = 7e-11
Identities = 60/268 (22%), Positives = 116/268 (43%), Gaps = 22/268 (8%)
Query: 490 VGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYI----ASYDGNIRCIDILTS 545
VGTYDG V L++ ++WQ + G + TY G LY+ A+ G++ +D +
Sbjct: 163 VGTYDGVVSAVALDDGEILWQTDAGDAAAASPTYLDGKLYVAIEHATPSGSVVKMDAESG 222
Query: 546 TIK-ETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPV 604
I+ ++ S + ++ ++FG+ G C W G + P
Sbjct: 223 EIEWRDERPTNHPHSTVAIDREHGRLIFGSNDGHCYAWSFPELEREWAYDTGGDV-KLP- 280
Query: 605 LYDNDKYVIFAEVNGEIHCRTVEKGIKIWTY----------NGAKGNIFSSLCVKEINKF 654
L ++ + G + VE G ++W + + + G+ +C ++
Sbjct: 281 LAISEGIAVVPSWAGTVTGLDVEDGSQLWEFETDGGETSRGDPSPGDTGGVMCAPAVH-- 338
Query: 655 KWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIH 714
++Y G HD+N Y++++ + W T + + ND +L S D KL+ +
Sbjct: 339 DGEVYVGSHDSNAYAIDLQTGEKL--WSTATGGWITGSAVATNDH-VLVGSYDAKLYALD 395
Query: 715 SELGTVTAQYQLPGETFSSPIICDDHVF 742
+ G+VT + G+ S+PI+ DD ++
Sbjct: 396 RDDGSVTWTAEGRGDVTSAPIVTDDGIY 423
Score = 35.5 bits (78), Expect = 5.4
Identities = 27/129 (20%), Positives = 51/129 (39%), Gaps = 9/129 (6%)
Query: 417 VQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPIL 476
+ W D G ASP + + + + SG +V M+A +G +++ R E P
Sbjct: 180 ILWQTDAGDAAAASPTYLDGKLYVAIEHATPSGSVVKMDAESG------EIEWRDERPTN 233
Query: 477 CVHDE-CVTSPCG--VVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASY 533
H + G + G+ DG + W + G +K +G+ + S+
Sbjct: 234 HPHSTVAIDREHGRLIFGSNDGHCYAWSFPELEREWAYDTGGDVKLPLAISEGIAVVPSW 293
Query: 534 DGNIRCIDI 542
G + +D+
Sbjct: 294 AGTVTGLDV 302
>UniRef50_Q8DTJ8 Cluster: Putative bacitracin synthetase; n=1;
Streptococcus mutans|Rep: Putative bacitracin synthetase
- Streptococcus mutans
Length = 1455
Score = 71.3 bits (167), Expect = 9e-11
Identities = 85/326 (26%), Positives = 149/326 (45%), Gaps = 33/326 (10%)
Query: 37 QTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGV 96
Q+TPS++ + + +L R LK++ +GGE L I ++L K + LYG
Sbjct: 733 QSTPSRWGIFTEDEQLMTLLKER--LKLVLVGGEKLTK-NIAEKLLSIGGK--LINLYGP 787
Query: 97 TEMSCWASVAEL-DLNKVTTGDKEVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCI 155
TE + WA +E+ D N++ G+ PL N T + + K + G++ L
Sbjct: 788 TEATVWAFASEVTDPNQIYLGE---PLNN---TTAYILDENGKESPKGELCLQGSGVSPG 841
Query: 156 LLNRKNGNKEE--NSIK-----FIDTGDIGEIRNGTVF-YRGRVDDTIKRFGHKINLHSI 207
NR ++ S+K TGDI E N + + GR DD +K G+++ L I
Sbjct: 842 YQNRPELTEKSFVKSLKHGNNILYHTGDIVEYTNDQDYLFIGRKDDQVKVNGYRVELGEI 901
Query: 208 ESTVMQCPRVRSCSCVWLQTPLLLIVYF-SAETLSSQELLDFLKCKLDEKYWPDKVIRVD 266
+S + + +++ ++ + LI + S E S E L L + P+ +I +
Sbjct: 902 DSIISKMSKIKRAKTIYQEETGNLIAFCESKEHCSDIETRKELSKILPKYMLPNSIIFLS 961
Query: 267 TLPTNAHGKTSKEILVNIY----KKSNIL-QNVENI---KSYLFKELKALVNKDLNYEDL 318
+P +GK L N Y KKS +L +NVE + + +L K K++ L+
Sbjct: 962 EMPLMINGKIDTSKLKNKYLQIAKKSLVLSENVEELSATQQHLIKIFKSVTGYALD---- 1017
Query: 319 QSKSFFSLGGTSFLAVTICNKLSLTF 344
+ ++FF +G +S + + L T+
Sbjct: 1018 RDENFFEVGISSLNILRVIQHLKKTY 1043
>UniRef50_Q7N5R3 Cluster: Complete genome; segment 7/17; n=1;
Photorhabdus luminescens subsp. laumondii|Rep: Complete
genome; segment 7/17 - Photorhabdus luminescens subsp.
laumondii
Length = 4160
Score = 71.3 bits (167), Expect = 9e-11
Identities = 84/343 (24%), Positives = 158/343 (46%), Gaps = 40/343 (11%)
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELF-VQPHEKN---NTMGK 144
RI YGVTE + ++V + + + + TG + +PLG L+ ELF V H + G+
Sbjct: 745 RILGSYGVTEATIDSTVFDPETHPLETG-RVIPLGRPLASCELFIVDKHLQQVPIGVSGE 803
Query: 145 IILASKTRKCILLNR--------------KNGN-------KEENSIKFIDTGDIG-EIRN 182
+++A T LN +G E +S +F T DI + +
Sbjct: 804 LLIAGVTVAKGYLNNPQLTAEKFITGKFDSHGRFVADGLVAENSSTRFYRTSDICCFLAD 863
Query: 183 GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL--QTPLLLIVYFSAETL 240
GT+ + GR D IK G ++ L +ES +++ VR C+ V T ++V + +
Sbjct: 864 GTIDFMGRSDHQIKIRGFRVELGEVESALLEHADVRQCAVVACNDSTNNKVLVAYVVSSA 923
Query: 241 SSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS-KEILVNIYKKSNILQNVENIKS 299
+ +L +L +L P + +D LPT +GK K + V + +++ +
Sbjct: 924 DTDKLRGYLSLRLPGHMMPRAFVFLDKLPTTPNGKVDRKRLQVPDFSLPENQESMTEPAN 983
Query: 300 YLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSH 358
++L AL L + + ++ +FF GG S +A + +++ TF K L + +H
Sbjct: 984 AREEQLLALWRTALGVQVISTEDNFFYCGGNSLIAANLITQINKTFSVQLK--LSAIFNH 1041
Query: 359 NKSIG--DVLKTITQDTNCLENKFKKSIKRNRSTSSHGENSIS 399
+G +L ++ +D+ +E K SI+++ S+ + S++
Sbjct: 1042 PTIVGLASLLGSVEKDS--IE---KNSIEKDGVEKSNAKQSVT 1079
Score = 50.0 bits (114), Expect = 2e-04
Identities = 48/183 (26%), Positives = 85/183 (46%), Gaps = 17/183 (9%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL---QTPL 229
TGDI R +G + + GRVD +K G++I L+++ + + P VR + + Q
Sbjct: 1910 TGDIVRQRMDGALEFIGRVDRQVKIRGYRIELNAVRAALSALPGVRQAEALAITDSQGNK 1969
Query: 230 LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI----- 284
L Y ET S E+L L+ ++ E P + +D LPT GK + L +
Sbjct: 1970 ELAGYIVGET-SRSEILSALRQQVSEVMVPTALFFLDALPTGITGKVDLKALAEMKLTRA 2028
Query: 285 --YKKSNILQNVENIKSYLFKELKALVNKD-LNYEDLQSKSFFSLGGTSFLAVTICNKLS 341
++ S + V + S + + L+ +D + Y++ +FF GG S + + +L+
Sbjct: 2029 GQHQSSPLPAKVVSSLSRVEAIWRELLERDEIGYDE----NFFDAGGHSLRVMALFQQLN 2084
Query: 342 LTF 344
F
Sbjct: 2085 EAF 2087
>UniRef50_A0UXD7 Cluster: Amino acid adenylation domain; n=1;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 1893
Score = 71.3 bits (167), Expect = 9e-11
Identities = 88/340 (25%), Positives = 154/340 (45%), Gaps = 34/340 (10%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
+LKV+ L GE + K L+ K + YG TE S AS +L K + +
Sbjct: 1372 SLKVVTLAGEKVPAKLATKSLQ-KREDLELVNEYGPTENSV-ASTVFRNLQKA----ENI 1425
Query: 121 PLGNCLSETELFVQPHEKNNTM-----GKIILASKTRKCILLNRKNGNKE-------ENS 168
+G ++ T +++ ++ N M G+I L+ LNR ++ E
Sbjct: 1426 LIGRPIANTRVYIL-NKYNQPMPIGVTGEICLSGDGVARGYLNRPELTQQKFVPDPFEQG 1484
Query: 169 IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT 227
TGD G+ + +G + Y GR+D +K G +I L IE+ +++ ++ + + +
Sbjct: 1485 KVMYKTGDSGKWLPDGNIEYIGRIDHQVKIRGFRIELGEIEARLIKHSSIKQAAVIDKEN 1544
Query: 228 ---PLLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L Y +AE L L FL+ +L + P + I VD LP +GK ++ L
Sbjct: 1545 GDGSKYLCAYIAAEKELQISTLRSFLQEELPDYMVPTQFIFVDKLPFTQNGKLDRKALQE 1604
Query: 284 IY---KKSNILQNVENIKSYLFKEL-KALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNK 339
I + + + Q +N L ++ K +++KD Y ++ +FF LGG S L + + K
Sbjct: 1605 ISGADRNAALYQPPDNSVETLVADIWKQVLDKD--YFG-RNDNFFDLGGNSILLMQVHAK 1661
Query: 340 LSLTFPEVGKHILPHLLSHNKSIGDVLKTITQDTNCLENK 379
L +P GK + L N ++ + +T+D N + K
Sbjct: 1662 LEKIYP--GKVKITDLFD-NSTVSKLAVLLTKDENHTDEK 1698
>UniRef50_O68006 Cluster: Bacitracin synthetase 1 (BA1) [Includes:
ATP-dependent isoleucine adenylase (IleA) (Isoleucine
activase); ATP-dependent cysteine adenylase (CysA)
(Cysteine activase); ATP-dependent leucine adenylase
(LeuA) (Leucine activase); ATP-dependent glutamate
adenylase (GluA) (Glutamate activase); ATP-dependent
isoleucine adenylase (IleA) (Isoleucine activase);
Glutamate racemase (EC 5.1.1.3)]; n=7; cellular
organisms|Rep: Bacitracin synthetase 1 (BA1) [Includes:
ATP-dependent isoleucine adenylase (IleA) (Isoleucine
activase); ATP-dependent cysteine adenylase (CysA)
(Cysteine activase); ATP-dependent leucine adenylase
(LeuA) (Leucine activase); ATP-dependent glutamate
adenylase (GluA) (Glutamate activase); ATP-dependent
isoleucine adenylase (IleA) (Isoleucine activase);
Glutamate racemase (EC 5.1.1.3)] - Bacillus licheniformis
Length = 5255
Score = 70.9 bits (166), Expect = 1e-10
Identities = 76/360 (21%), Positives = 163/360 (45%), Gaps = 27/360 (7%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNS--VTFWQTTPSKFFQHSNENIKNKILCARS 60
++ A ++GASL+I D +V ++ +T W + P+ ++ N++
Sbjct: 1273 DVFGALSSGASLVIIDDQRDVFSLKETAEKERITIWNSVPAIMGMTADVYPDNEL---NH 1329
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
L+++ L G+ + +++ +K + +L G TE S W+ + KV K +
Sbjct: 1330 HLRLILLSGDWIP-LQLPATIKKTFKNAEVISLGGATEGSIWSIY--YPIQKVEEDWKSI 1386
Query: 121 PLGNCLSETELFVQPHEKN----NTMGKIIL--ASKTRKCILLNRKNGNK--EENSIKFI 172
P G L+ +++V K G++ + A I K + + + +I
Sbjct: 1387 PYGKPLANQKIYVLNQNKQLCPVGVEGELYIGGAGVASGYIHDQEKTEHSFIQHQELGYI 1446
Query: 173 -DTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP-- 228
TGD G ++ +G V + GR D +K G+++ + IE+T++ + S + +P
Sbjct: 1447 YKTGDYGVLKEDGYVEFLGRKDSQVKIRGYRVEMGEIENTLVSHQEITKASVIDYTSPDG 1506
Query: 229 -LLLIVYFSAETLSSQ-ELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L + AE SQ ++ +FL+ L + P K ++++ +P +GK K L ++ +
Sbjct: 1507 IKNLYAFVVAENAISQLDVKEFLQKTLPDYMIPAKFVQIEEIPLTVNGKVDKRTLHDLAE 1566
Query: 287 KSNILQNVENIKSYLFKELKAL---VNKDL-NYEDLQ-SKSFFSLGGTSFLAVTICNKLS 341
+ + + E +A+ + KD+ + + S++ +GG S A++I +++
Sbjct: 1567 QHTADEGQRGGRMLPENETQAMLLEIWKDIFGLDSINLDVSYYEIGGDSLKAISIITEIN 1626
Score = 67.3 bits (157), Expect = 1e-09
Identities = 74/333 (22%), Positives = 149/333 (44%), Gaps = 27/333 (8%)
Query: 62 LKVLALGGEPLNGIKILKELKHK--NNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
+K L +GG+ L ++ L HK N I +YG TE A+ +++ KV
Sbjct: 3407 VKELIVGGDALTP-DVIGGLFHKFPNLSCNITNVYGPTECCVDAASHQIESGKVPQ-TPS 3464
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE-------ENS 168
+P+G L T +++ E G++ +A + +NR E E
Sbjct: 3465 IPIGRPLLNTSIYIVDKELRPLPVGIAGELCIAGEGVARGYVNRPELTAEKFVDHPFEPG 3524
Query: 169 IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT 227
K TGD+ + +G + + GR D +K G++I L +E ++ +++ + + +
Sbjct: 3525 KKMYKTGDLAMWLPDGQIEFLGRADHQVKIRGYRIELGEVEQQLLTHEKIKEAAVIAGKD 3584
Query: 228 P---LLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L Y +++ L + ++ FL+ ++ + P +++D LP GK + L
Sbjct: 3585 QNGNSYLCAYIASDKELPAADVRQFLEREMPDYMIPSYFVKLDRLPRTPSGKVDRSALPE 3644
Query: 284 IYKKSNILQNV--ENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
N+++ + ++ + ++L + + L ED+ S FF+ GG S A+ I ++L
Sbjct: 3645 ADGNVNVMEGTGYDPPRNEIERKLVQVWREILGAEDIGISHHFFAAGGDSIKALQIVSRL 3704
Query: 341 SLTFPEVGKHILPHLLSHNKSIGDVLKTITQDT 373
+ ++ + L N I D+ + IT++T
Sbjct: 3705 A----KMNLKLEMKALFANPKIKDLSRFITEET 3733
Score = 67.3 bits (157), Expect = 1e-09
Identities = 82/363 (22%), Positives = 154/363 (42%), Gaps = 29/363 (7%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDND----NSVTFWQTTPSKFFQHSNENIKNKILCA 58
+I A NGASL++ T + HE + V+ T + F ++ NI C
Sbjct: 4861 DIFGALLNGASLVLIEKETVLNTHELAEVIKKEQVSVMFITTALFNTLADINIG----CL 4916
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
K+L GGE + + K L H + ++ +YG TE + +A+ +N++ +
Sbjct: 4917 AKLRKIL-FGGERASIPHVRKVLDHVG-RDKLIHVYGPTESTVYATY--YFINEIDDEAE 4972
Query: 119 EVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE-------N 167
+P+G+ L+ T + + G++ +A LNR+ E+
Sbjct: 4973 TIPIGSPLANTSVLIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIP 5032
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+ + + +G + + GR+D +K G +I L IES + + +
Sbjct: 5033 GERLYKTGDLAKWLPDGNIEFIGRIDHQVKIRGFRIELGEIESRLEMHEDINETIVTVRE 5092
Query: 227 ----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
P + + +S EL FL KL + P +++D LP +GK ++ L
Sbjct: 5093 DEESRPYICAYITANREISLDELKGFLGEKLPDYMIPAYFVKMDKLPLTKNGKVDRKALP 5152
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLS 341
+ + E ++Y+ + + +++ L E + S FF GG S A+ + ++
Sbjct: 5153 EPDRSAGTEAEYEAPRNYVEQRIISILEDVLGTERMGISCHFFDKGGNSLKAMQAVHSIN 5212
Query: 342 LTF 344
TF
Sbjct: 5213 KTF 5215
Score = 59.3 bits (137), Expect = 4e-07
Identities = 65/298 (21%), Positives = 126/298 (42%), Gaps = 20/298 (6%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S L+ + GGE + + K L H + ++ +YG TE + +A+ +N++ +
Sbjct: 290 SNLRKILFGGERASIPHVRKVLNHVG-RDKLIHVYGPTESTVYATY--YFINEIDDEAET 346
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE-------NS 168
+P+G+ L+ T + + G++ +A LNR+ E+
Sbjct: 347 IPIGSPLANTSVLIMDEAGKLVPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPG 406
Query: 169 IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ- 226
+ TGD+ + + +G + + GR+D +K G +I L IES + + +
Sbjct: 407 ERLYKTGDLAKWLPDGNIEFIGRIDHQVKIRGFRIELGEIESRLEMHEDINETIVTVRED 466
Query: 227 ---TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
P + + +S EL FL KL E P +++D LP +GK ++ L
Sbjct: 467 EESRPYICAYITANREISLDELKGFLGEKLPEYMIPAYFVKLDKLPLTKNGKVDRKALPE 526
Query: 284 IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFS-LGGTSFLAVTICNKL 340
+ + E ++ ++L A+ L+ E F+ +GG S A+ + K+
Sbjct: 527 PDRTAGAENEYEAPRNETEEKLAAVWQDVLHVEKAGIHDHFAQMGGHSLHAMELIAKI 584
Score = 53.2 bits (122), Expect = 2e-05
Identities = 60/297 (20%), Positives = 128/297 (43%), Gaps = 30/297 (10%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
+L+ L GG+ LN + KE ++ I YG TE + A+ +D + + +
Sbjct: 2378 SLRTLLTGGDKLN---VFKEKSYQ-----IVNNYGPTENTVVATSFPIDKSH-----QNI 2424
Query: 121 PLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKN-------GNKEENSI 169
P+G + ++++ + G++ +A + +NR GN
Sbjct: 2425 PIGKPIDNVKVYILNKDLQLCPLGASGELCIAGEGLARGYVNRPELTREKFIGNPFVPGE 2484
Query: 170 KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT- 227
+ TGD+ + + +G + + GRVD +K G++I IE+ +++ ++ + + +
Sbjct: 2485 RMYRTGDLAKMLPDGNIQFLGRVDQQVKIRGYRIEPGEIENRLLKYEKIEEAAVIAREDG 2544
Query: 228 ---PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
P L + + +++ FLK L + P +++D LP +GK K+ L
Sbjct: 2545 DHDPYLCAYVTVKKEVEPEKIRAFLKKSLPDYMIPQYFVQLDGLPLTVNGKVDKKSLPVP 2604
Query: 285 YKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKS-FFSLGGTSFLAVTICNKL 340
+ + + E + + ++L ++ + L + S FF GG S A + + +
Sbjct: 2605 ERSVTMDRRYEAPRDQMEEKLVSIWEEALGINKIGINSHFFEAGGHSLKAAALVSTI 2661
>UniRef50_Q3M5M7 Cluster: Amino acid adenylation; n=1; Anabaena
variabilis ATCC 29413|Rep: Amino acid adenylation -
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length = 1786
Score = 70.1 bits (164), Expect = 2e-10
Identities = 52/180 (28%), Positives = 88/180 (48%), Gaps = 9/180 (5%)
Query: 174 TGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--- 229
TGD+ R+ GT+ + GR+D +K G +I L IE+ + Q P+VR C + L
Sbjct: 1550 TGDLARYRSDGTIEFIGRIDHQVKIRGFRIELGEIETALNQHPQVRECVVIASDDQLAHQ 1609
Query: 230 ---LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI-Y 285
IV+ + S EL FLK KL E P +++ +P + K ++ L +
Sbjct: 1610 QLQAYIVFHQQLKVDSSELHRFLKQKLPEYMIPTSFFQLENIPLTPNAKIDRQALNRLGV 1669
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
+NI N +++ + L + + LN + + +FF LGG S LA+ + N+++ F
Sbjct: 1670 LINNIEVNRVAPSNHIEEVLANIWTEVLNLKQVGIHNNFFELGGNSLLAMQLLNRVNEAF 1729
>UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin
synthetase C-related non- ribosomal peptide synthetase
module; n=8; Proteobacteria|Rep: Arthrofactin
synthetase/syringopeptin synthetase C-related non-
ribosomal peptide synthetase module - Bradyrhizobium sp.
(strain BTAi1 / ATCC BAA-1182)
Length = 8646
Score = 70.1 bits (164), Expect = 2e-10
Identities = 72/298 (24%), Positives = 128/298 (42%), Gaps = 22/298 (7%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ L +GG+ L+ I L+H + + YG TE + +A E+ +V +P
Sbjct: 4002 LRYLLVGGDVLDPRSIRHVLRHSRPQ-HLLNGYGPTETTTFAITHEI--TEVDERASSIP 4058
Query: 122 LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---------ENS 168
LG +S T +++ + G+I + LNR E E
Sbjct: 4059 LGRPISNTRIYILDAYGDPVPIGVAGEIYIGGAGVARGYLNRPELTAERFVEDRFSGEAG 4118
Query: 169 IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ- 226
+ TGD+G + +GT+ Y GR D +K G +I L IE+ + + VR + + +
Sbjct: 4119 ARLYRTGDLGRWLEDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVIARED 4178
Query: 227 ---TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L+ Y S + ++EL L +L + P + + LP +GK ++ L
Sbjct: 4179 VAGDKRLVAYYVSDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTPNGKLDRKALPA 4238
Query: 284 IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ +Q E + + + + L E + + +FF+LGG S LAVT+ ++
Sbjct: 4239 PEGAAFAVQAYEPPQGETEAAIARIWAELLGVERIGRHDNFFALGGHSLLAVTLVERM 4296
Score = 69.7 bits (163), Expect = 3e-10
Identities = 72/298 (24%), Positives = 129/298 (43%), Gaps = 22/298 (7%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ L +GG+ L+ I L+H + + YG TE + +A E+ +V +P
Sbjct: 5078 LRYLLVGGDVLDPRSIRHVLRHSRPQ-HLLNGYGPTETTTFAITHEI--TEVDERASSIP 5134
Query: 122 LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---------ENS 168
LG +S T +++ + G+I + LNR E E
Sbjct: 5135 LGRPISNTRIYILDAYGDPVPIGVAGEIYIGGAGVARGYLNRPELTAERFVEDRFSGEAG 5194
Query: 169 IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT 227
+ TGD+G + +GT+ Y GR D +K G +I L IE+ + + VR + + +
Sbjct: 5195 ARLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDVAVIARED 5254
Query: 228 PL----LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L+ Y S + ++EL L +L + P + ++ LP +GK ++ L
Sbjct: 5255 VAGDKRLVAYYVSDAAIGAEELRGHLAARLPDYMVPSAYVHLERLPLTPNGKLDRKALPA 5314
Query: 284 IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ +Q E + + + + L E + + +FF+LGG S LAVT+ ++
Sbjct: 5315 PEGAAFAVQAYEPPQGETEAAIARIWAELLGVERIGRHDNFFALGGHSLLAVTLVERM 5372
Score = 65.7 bits (153), Expect = 4e-09
Identities = 71/300 (23%), Positives = 129/300 (43%), Gaps = 23/300 (7%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
+++K + GE L+ + + L + T + LYG TE + V K + D
Sbjct: 1845 TSVKRVMCSGEALSPV-LAARLLERLEGTELHNLYGPTEAA--VDVTAWRCAKEAS-DAS 1900
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---------E 166
VP+G +S T++++ + G+I + LNR E E
Sbjct: 1901 VPIGRPISNTQIYILDQHGDPVPIGVAGEIHIGGVQVGRGYLNRPELTAERFVEDRFSGE 1960
Query: 167 NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
+ TGD+G + +GT+ Y GR D +K G +I L IE+ + + VR + +
Sbjct: 1961 AGARLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHAAVRDAAVIAR 2020
Query: 226 Q----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
+ L+ Y S + ++EL L +L + P + ++ LP +GK ++ L
Sbjct: 2021 EDAPGDQRLVAYYVSDAAIGAEELRGHLAARLPDYMVPSAYVHLERLPLTPNGKLDRKAL 2080
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ +Q E + + + + L E + + +FF+LGG S LAVT+ ++
Sbjct: 2081 PAPEGAAFAVQAYEPPQGETEAAIARIWAELLGVERIGRHDNFFALGGHSLLAVTLVERM 2140
Score = 65.3 bits (152), Expect = 6e-09
Identities = 78/343 (22%), Positives = 144/343 (41%), Gaps = 30/343 (8%)
Query: 17 APDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIK 76
A D+ + ++VTF T PS + +KN+ T++ + +GGEPL
Sbjct: 2888 AVDVVRNVLELTKQSNVTFLNTVPSAL----DALLKNESF--PETVRTVNVGGEPLKR-S 2940
Query: 77 ILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPH 136
+ ++L + LYG TE + +++ + + +G +S T++++
Sbjct: 2941 LAEQLFATTQVELLRNLYGPTETTVYSTSVLMRRGEPFAAH----IGRPISNTQIYILDE 2996
Query: 137 EKN----NTMGKIILASKTRKCILLNRKNGNKE---------ENSIKFIDTGDIGE-IRN 182
G+I + LNR E E TGD+G + +
Sbjct: 2997 HGEPAPIGVAGEIYIGGAGVARGYLNRPALTAERFVEDRFSGEAGALLYRTGDLGRWLGD 3056
Query: 183 GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ----TPLLLIVYFSAE 238
GT+ Y GR D +K G +I L IE+ + + VR + + + L+ Y S
Sbjct: 3057 GTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVIAREDVAGDKRLVAYYVSDA 3116
Query: 239 TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIK 298
+ ++EL L +L + P + + LP +GK ++ L + +Q E +
Sbjct: 3117 AIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTLNGKLDRKALPAPEGAAFAVQAYEPPQ 3176
Query: 299 SYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ +EL + + L + + +FF+LGG S LAVT+ ++
Sbjct: 3177 GKIEEELARIWEELLGVARVGRHDNFFALGGHSLLAVTLVERM 3219
Score = 65.3 bits (152), Expect = 6e-09
Identities = 71/300 (23%), Positives = 128/300 (42%), Gaps = 23/300 (7%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
+++K + GE L+ + + L + T + LYG TE + V K + D
Sbjct: 7222 TSVKRVMCSGEALSPV-LAARLLERLEGTELHNLYGPTEAA--VDVTAWRCAKEAS-DAS 7277
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---------E 166
VP+G +S T++++ + G+I + LNR E E
Sbjct: 7278 VPIGRPISNTQIYILDQHGDPVPIGVAGEIHIGGVQVGRGYLNRPELTAERFVEDRFSGE 7337
Query: 167 NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
+ TGD+G + +GT+ Y GR D +K G +I L IE+ + + VR + +
Sbjct: 7338 AGARLYRTGDLGRWLEDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVIAR 7397
Query: 226 Q----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
+ L+ Y S + ++EL L +L + P + + LP +GK ++ L
Sbjct: 7398 EDVAGDKRLVAYYVSDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTPNGKLDRKAL 7457
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ +Q E + + + + L E + + +FF+LGG S LAVT+ ++
Sbjct: 7458 PAPEGAAFAVQAYEPPQGETEMAIARIWAELLGVERIGRHDNFFALGGHSLLAVTLVERM 7517
Score = 64.1 bits (149), Expect = 1e-08
Identities = 78/343 (22%), Positives = 144/343 (41%), Gaps = 30/343 (8%)
Query: 17 APDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIK 76
A D+ + ++VTF T PS + +KN+ T++ + +GGEPL
Sbjct: 6120 AVDVVRNVLELTKQSNVTFLNTVPSAL----DALLKNESF--PETVRTVNVGGEPLKR-S 6172
Query: 77 ILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPH 136
+ ++L + LYG TE + +++ + + +G +S T++++
Sbjct: 6173 LAEQLFATTQVELLRNLYGPTETTVYSTSVLMRRGEPFAAH----IGRPISNTQIYILDE 6228
Query: 137 EKN----NTMGKIILASKTRKCILLNRKNGNKE---------ENSIKFIDTGDIGE-IRN 182
G+I + LNR E E TGD+G + +
Sbjct: 6229 HGEPAPIGVAGEIYIGGAGVARGYLNRPALTAERFVEDRFSGEAGALLYRTGDLGRWLGD 6288
Query: 183 GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ----TPLLLIVYFSAE 238
GT+ Y GR D +K G +I L IE+ + + VR + + + L+ Y S
Sbjct: 6289 GTIAYLGRNDFQVKIRGFRIELGEIEARLSEHADVRDAAVIAREDVAGDKRLVAYYVSDA 6348
Query: 239 TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIK 298
+ ++EL L +L + P + + LP +GK ++ L + +Q E +
Sbjct: 6349 AIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTLNGKLDRKALPAPEGAAFAVQAYEPPQ 6408
Query: 299 SYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ +EL + + L + + +FF+LGG S LAV + ++L
Sbjct: 6409 GKIEEELARIWEELLGVARVGRHDNFFALGGHSLLAVQLVSRL 6451
Score = 59.7 bits (138), Expect = 3e-07
Identities = 47/181 (25%), Positives = 84/181 (46%), Gaps = 6/181 (3%)
Query: 166 ENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW 224
E + TGD+G + +GT+ Y GR D +K G +I L IE+ + + VR + +
Sbjct: 870 EAGARLYRTGDLGRWLSDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHAGVRDVAVIA 929
Query: 225 LQ----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
+ L+ Y S + ++EL L +L + P + ++ LP +GK ++
Sbjct: 930 REDAPGDQRLVAYYVSDAAIGAEELRGHLAARLPDYMVPSAYVHLERLPLTPNGKLDRKA 989
Query: 281 LVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNK 339
L + +Q E + L + + L E + + +FF+LGG S LAVT+ +
Sbjct: 990 LPAPEGAAFAVQAYEPPQGETEAALARIWAELLGVERIGRHDNFFALGGHSLLAVTLVER 1049
Query: 340 L 340
+
Sbjct: 1050 M 1050
Score = 56.4 bits (130), Expect = 3e-06
Identities = 46/181 (25%), Positives = 83/181 (45%), Gaps = 6/181 (3%)
Query: 166 ENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW 224
E + TGD+G + +GT+ Y GR D +K G +I L IE+ + + VR + +
Sbjct: 8417 EAGARLYRTGDLGRWLGDGTIAYLGRNDFQVKIRGFRIELGEIEARLSEHAAVRDVAVIA 8476
Query: 225 LQ----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
+ L+ Y S + ++EL L +L + P + + LP +GK ++
Sbjct: 8477 REDGPGDKRLVAYYVSDAAIGAEELRGHLAARLPDYMVPSAYVHLQRLPLTPNGKLDRKA 8536
Query: 281 LVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNK 339
L + +Q E + + + ++ L E + + +FF+LGG S LAV + +
Sbjct: 8537 LPAPEGDAFAVQAYEPPQGETEAAIARIWSELLGVERIGRHDNFFALGGHSLLAVMLVVR 8596
Query: 340 L 340
L
Sbjct: 8597 L 8597
>UniRef50_Q4ZT67 Cluster: Amino acid adenylation; n=15; Bacteria|Rep:
Amino acid adenylation - Pseudomonas syringae pv.
syringae (strain B728a)
Length = 13537
Score = 69.7 bits (163), Expect = 3e-10
Identities = 77/306 (25%), Positives = 133/306 (43%), Gaps = 26/306 (8%)
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
A + L+ L +GG+ L+ I + L + + YG TE + +++ E+ + G
Sbjct: 798 ALARLRYLIVGGDVLDPAVIARVLA-EGAPQHLLNGYGPTEATTFSTTHEI----TSVGS 852
Query: 118 KEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGN---------K 164
+P+G + ++++V + G++ + + LNR N
Sbjct: 853 GGIPIGRPIGNSQVYVLDTLRQPVAVGVAGELYIGGQGVAKGYLNRPELNATQFVANPFS 912
Query: 165 EENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
++ TGD+G +G V Y GR DD +K G +I L IE+ +++CP VR +
Sbjct: 913 DDAGALLYRTGDLGRWNADGIVEYLGRNDDQVKIRGFRIELGEIEARLVECPGVREAVVL 972
Query: 224 WLQTPLL---LIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
Q L+ Y E LS+ EL L L E P + +D+ P A+GK
Sbjct: 973 ARQDESAHKRLVAYVVGEENSALSAVELRRELAASLAEYMVPSAFMVLDSFPLTANGKLD 1032
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTI 336
+ L + + E + + L L ++ LN E + + FF LGG S LAV++
Sbjct: 1033 RRALPVPDADAYASREFEAPEGEVEITLARLWSELLNVERVGRHDHFFELGGHSLLAVSL 1092
Query: 337 CNKLSL 342
++ L
Sbjct: 1093 IERMRL 1098
Score = 61.7 bits (143), Expect = 7e-08
Identities = 86/366 (23%), Positives = 150/366 (40%), Gaps = 33/366 (9%)
Query: 3 EILLACTNGASLLIAPDLT----EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCA 58
EI A +G LLI P L E ++ VT TPS F Q +N
Sbjct: 8314 EIWGALLHGGRLLIVPQLVSRSPEDFYNLLCSAGVTVLNQTPSAFRQLIAAQAENT---Q 8370
Query: 59 RSTLKVLALGGEPLNGIKILKE--LKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
+L+ + GGE L +LK + N T++ +YG+TE + + L
Sbjct: 8371 AHSLRQVIFGGEALE-TAMLKPWYARQANAGTQLVNMYGITETTVHVTYYPLQPEDAQRL 8429
Query: 117 DKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRK---------NGN 163
P+G + + +L+V +G++ + LNR+ N
Sbjct: 8430 GAS-PIGRRIPDLQLYVLDARGEPVPVGVVGELYVGGAGVARGYLNREALTAERFLDNPF 8488
Query: 164 KEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
+ TGD+G + +G++ Y GR D+ +K G +I L IE+ + + P VR
Sbjct: 8489 SHTADARMYRTGDLGRWLADGSLEYLGRNDEQVKIRGFRIELGEIEARLAEYPDVRDAVV 8548
Query: 223 VWLQT---PLLLIVYFSAET----LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGK 275
+ + L+ Y +A+ L + L + L+ L E P +++D LP A+GK
Sbjct: 8549 LCREDVPGDKRLVAYVTAQQPESLLDIESLREHLQGALPEHMVPAAYVQLDELPLTANGK 8608
Query: 276 TSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAV 334
++ L + + + ++ + + L E + + +FF LGG S LAV
Sbjct: 8609 LDRKALPVPDRSALASRGYAAPENDTEMAIARIWQDLLQLEQVGRHDNFFELGGHSLLAV 8668
Query: 335 TICNKL 340
+ ++
Sbjct: 8669 KLIERM 8674
Score = 57.6 bits (133), Expect = 1e-06
Identities = 82/365 (22%), Positives = 148/365 (40%), Gaps = 32/365 (8%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDND----NSVTFWQTTPSKFFQHSNENIKNKILCA 58
EI A +G LLI P L + +D VT TPS F Q +N+
Sbjct: 3975 EIWGALLHGGRLLIVPQLVSRSPRDFHDLLCSAGVTVLNQTPSAFRQLIAAQGENE---Q 4031
Query: 59 RSTLKVLALGGEPLNGIKILKE--LKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
+L+ + GGE L +LK + N T++ +YG+TE + + L
Sbjct: 4032 AHSLRQVIFGGEALE-TAMLKPWYARQANAGTQLVNMYGITETTVHVTYYPLQPEDAQRL 4090
Query: 117 DKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---ENSI 169
P+G + + +L+V +G++ + LNR+ E +N
Sbjct: 4091 GAS-PIGRRIPDLQLYVLDARGEPVPVGVVGELYVGGAGVARGYLNREALTAERFIDNPF 4149
Query: 170 ------KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
+ TGD+G + +G++ Y GR D+ +K G +I L IE+ ++ C V+
Sbjct: 4150 NTAPGARLYRTGDLGRWLADGSLEYLGRNDEQVKIRGFRIELGEIEAQLVACDGVQDAMV 4209
Query: 223 VWLQTP------LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
+ + + ++ + L + L + L+ L E P + ++ P A+GK
Sbjct: 4210 LVREDEPGDKRLVAYVIGTAGAELDATHLREQLRLSLAEYMLPSAFVSLEAFPLTANGKL 4269
Query: 277 SKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVT 335
++ L + + + E + + + L E + + FF LGG S LAV
Sbjct: 4270 DRKALPAPDRSAVASRGYEAPEGDTEMAIARIWQDLLQLEQVGRHDHFFELGGHSLLAVK 4329
Query: 336 ICNKL 340
+ ++
Sbjct: 4330 LIERM 4334
Score = 54.0 bits (124), Expect = 1e-05
Identities = 83/365 (22%), Positives = 150/365 (41%), Gaps = 32/365 (8%)
Query: 3 EILLACTNGASLLIAPDLT----EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCA 58
EI A +G LLI P L + + + VT TPS F Q N ++
Sbjct: 5062 EIWGALLHGGRLLIVPQLVSRSPQDCYALLCNAGVTVLNQTPSAFRQLLNAQGESD---Q 5118
Query: 59 RSTLKVLALGGEPLNGIKILKELKHK--NNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
R +L+ + GGE L+ +LK + N T++ +YG+TE + + L
Sbjct: 5119 RHSLRQVIFGGEALD-TGMLKPWYARVINAGTQLVNMYGITETTVHVTYHPLVAADAQRS 5177
Query: 117 DKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRK---------NGN 163
P+G + + +L+V + +G++ + LNR+ N
Sbjct: 5178 GVS-PIGVRIPDLQLYVLDARREPVPVGVVGELYVGGAGVARGYLNREALTAERFLANPF 5236
Query: 164 KEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
+E + TGD+G + +G++ Y GR DD +K G +I L I++ + C VR
Sbjct: 5237 SKEPQARLYRTGDLGRWMADGSLDYLGRNDDQVKIRGFRIELGEIQAVLAACNTVREALV 5296
Query: 223 VWLQT---PLLLIVYFSA---ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
+ + L+ Y A + + +L L L + P + +D+ P A+GK
Sbjct: 5297 LVREDQPGDKRLVAYVIAAPGHEIVAADLRAQLLLSLADHMVPSAFVALDSFPLTANGKL 5356
Query: 277 SKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVT 335
++ L ++ ++ + + + + L + + FF LGG S LAV
Sbjct: 5357 DQKALPAPDAQALAMREYAPPEGDVEIAIAQIWQSLLQVPQVGRHDHFFELGGHSLLAVK 5416
Query: 336 ICNKL 340
+ ++
Sbjct: 5417 LIERM 5421
Score = 52.8 bits (121), Expect = 3e-05
Identities = 65/296 (21%), Positives = 126/296 (42%), Gaps = 27/296 (9%)
Query: 67 LGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCL 126
+ GE L ++++L + R+ LYG +E + ++S +D + P+GN
Sbjct: 7296 VAGEALKR-SLVEDLFERTGVQRLCNLYGPSETTTYSSWVAMDREQGFAAHIGKPVGN-- 7352
Query: 127 SETELFVQPHEKN----NTMGKIILASKTRKCILLNR---------KNGNKEENSIKFID 173
T+ ++ ++ G+I + LNR K+ + + +
Sbjct: 7353 --TQFYLLDEQQQPVPLGVSGEIYIGGAGVARGYLNRDDLTAERFLKDPFSQNPAARMYR 7410
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT---PL 229
TGD+G + +G + Y GR DD +K G +I L I++ + + P V +
Sbjct: 7411 TGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAVHEAVVTAREDVPGDK 7470
Query: 230 LLIVYFSAETLSSQELLDFLKCKLDEK---YW-PDKVIRVDTLPTNAHGKTSKEILVNIY 285
L+ Y++ + +D L+ L E+ Y P + +D LP +GK ++ L
Sbjct: 7471 RLVAYYTLSAGHASVDIDSLRGWLQEQLPAYMIPVAYVLLDALPLTPNGKLDRKALPAPE 7530
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ I + E + ++ A+ L + + +FF LGG S LAV++ ++
Sbjct: 7531 ADALISRGYEAPQGETETQIAAIWQDLLGVAQVGRHDNFFELGGHSLLAVSLIGRM 7586
Score = 51.6 bits (118), Expect = 8e-05
Identities = 66/303 (21%), Positives = 126/303 (41%), Gaps = 27/303 (8%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
+++ + + GE L +++ L K R+ LYG +E + ++S +D
Sbjct: 2949 TSVHTVNVAGEALKR-SLVESLFEKTGVRRLCNLYGPSETTTYSSWVAMDREDGFAAHIG 3007
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---------E 166
P+GN T+ ++ ++ G+I + LNR E +
Sbjct: 3008 KPVGN----TQFYLLDEQQQPVPLGVAGEIYIGGAGVARGYLNRDELTAERFLTDPFSQQ 3063
Query: 167 NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW- 224
+ + TGD+G + +G + Y GR DD +K G +I L I++ + + P V
Sbjct: 3064 PAARMYRTGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAVHEAVVTAR 3123
Query: 225 --LQTPLLLIVYFSAE----TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
+ L+ Y++ ++ S L +L+ +L P + +D +P +GK +
Sbjct: 3124 EDIPGDKRLVAYYTLSAGHASVDSDSLRGWLQEQLPAHMIPAAYVLLDAMPLTPNGKLDR 3183
Query: 279 EILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTIC 337
+ L + I E + L + + LN E + + FF LGG S LAV++
Sbjct: 3184 KALPAPDGDALIRGGYEAPQGTAEITLAKIWSDLLNIERVGRHDHFFELGGHSLLAVSLI 3243
Query: 338 NKL 340
++
Sbjct: 3244 ERM 3246
Score = 50.0 bits (114), Expect = 2e-04
Identities = 68/302 (22%), Positives = 127/302 (42%), Gaps = 23/302 (7%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTE--MSCWASVAELDLNKVTTGDKE 119
++++ + G+ L+ K+ + + TR+ YG TE +SC A+ D + G
Sbjct: 11581 VRLINVTGDALSAQKLKLWDEVRPAHTRLINTYGPTEATVSCTAAYVSHDAAAGSEGSGN 11640
Query: 120 VPLGNCLSETELFV-QPHEKN---NTMGKIILASKTRKCILLNRKNGNKEE-------NS 168
+G ++ T +++ H++ G+I + LN + N E NS
Sbjct: 11641 ATIGKPMANTRIYLLDAHQQPVPYGVAGEIFIGGDGVARGYLNLEEVNAERFLADPFSNS 11700
Query: 169 --IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
+ TGD+ + +G + Y GR D +K G +I L IE+ + C V+ +
Sbjct: 11701 PEARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCTGVKEAVVIAR 11760
Query: 226 Q-TP--LLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
+ TP L+ Y + +L + L L +L E P + +D LP + K ++
Sbjct: 11761 EDTPGDKRLVAYVVGQPQASLDAASLHAELAPQLAEYMLPSAFVILDALPLTPNRKLDRK 11820
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICN 338
L ++ + + L + LN E + + FF LGG S LA+ + +
Sbjct: 11821 ALPAPQAEAFASREHVEPQGDTEMALAQIWQNLLNLEQVGRHDQFFELGGHSLLAMRLIS 11880
Query: 339 KL 340
++
Sbjct: 11881 QV 11882
Score = 49.2 bits (112), Expect = 4e-04
Identities = 68/302 (22%), Positives = 125/302 (41%), Gaps = 23/302 (7%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTE--MSCWASVAELDLNKVTTGDKE 119
++++ + G+ L+ K+ + + TR+ YG TE +SC A+ D + G
Sbjct: 10513 VRLINVTGDALSAQKLKLWDEVRPAHTRLINTYGPTEATVSCTAAYVSHDAAAGSEGSGN 10572
Query: 120 VPLGNCLSETELFV-QPHEKN---NTMGKIILASKTRKCILLNRKNGNKEE-------NS 168
+G ++ T +++ H++ G+I + LN + N E NS
Sbjct: 10573 ATIGKPMANTRIYLLDEHQQPVPYGVAGEIFIGGDGVARGYLNLEEVNAERFLADPFSNS 10632
Query: 169 --IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
+ TGD+ + +G + Y GR D +K G +I L IE+ + C V+ +
Sbjct: 10633 PDARMYKTGDLARYMADGRIEYLGRNDFQVKVRGFRIELGEIEARLGNCKGVKEAVVIAR 10692
Query: 226 QT---PLLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
+ L+ Y A+ L + L L +L E P + +D LP + K ++
Sbjct: 10693 EDNPGEKRLVAYVIAQPQANLDAASLRAELAPQLAEYMLPSAFVLLDALPLTPNRKLDRK 10752
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICN 338
L + + + K L + LN E + + FF LGG S LA+ + +
Sbjct: 10753 ALPAPADDAFASREHVAPQGTSEKALAQIWQNLLNLEAVGRHDHFFELGGHSLLAMRLIS 10812
Query: 339 KL 340
++
Sbjct: 10813 QV 10814
Score = 48.8 bits (111), Expect = 5e-04
Identities = 44/176 (25%), Positives = 83/176 (47%), Gaps = 9/176 (5%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW---LQTPL 229
TGD+G + NG + Y GR D +K G +I + IE+ + + P V +
Sbjct: 6336 TGDVGRWLANGALEYLGRNDFQVKIRGLRIEIGEIEAALAKHPAVHEAVVTAREDIPGDK 6395
Query: 230 LLIVYF--SAE--TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
L+ Y+ SAE + + L L+ +L E P + ++ +P ++GK ++ L
Sbjct: 6396 RLVAYYTQSAEHTAVDIETLRGHLQQQLPEYMVPAIYVLLEAMPLTSNGKLDRKALPAPD 6455
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ I + E + + +++ + L E + + +FF LGG S LAV++ ++
Sbjct: 6456 GDALISRGYEAPQGEIEEQIAIIWQDLLGVEQVGRHDNFFELGGHSLLAVSLTGRM 6511
Score = 48.8 bits (111), Expect = 5e-04
Identities = 72/306 (23%), Positives = 127/306 (41%), Gaps = 27/306 (8%)
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
A + L++L GGE + + +H +++ R+F YG TE + A+ ++ V G
Sbjct: 12635 ALAGLRMLECGGERADPASFRRVREH-SSQVRLFNGYGPTEATTCAT--RYEVFDVQPGT 12691
Query: 118 KEVPLGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKEENS---- 168
+P+G + +++ +P + +G+I + LNR + E S
Sbjct: 12692 LSLPIGKPNANVRIYLLDVCGEPVPMGS-VGEIYIGGVGVALGYLNRPELSAERFSDDPF 12750
Query: 169 -----IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
+ TGD+ + +G + Y R D +K G ++ L +ES++ C VR+
Sbjct: 12751 SQQAGARLYRTGDLARWLPDGNLEYLARNDGQVKVRGFRVELGEVESSLHGCDGVRNSVV 12810
Query: 223 VWLQ-TP--LLLIVYFSA----ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGK 275
V + +P L+ Y++ E + L L L E P I + LP +GK
Sbjct: 12811 VAREDSPGDTRLVAYYTVHADVEAPEPEALRAQLSAGLPEYMVPSVFICLPDLPLTLNGK 12870
Query: 276 TSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAV 334
+ L + E L L + L + + + SFF LGG S +AV
Sbjct: 12871 VDVQALPAPTADQFANRAFEAPAGELEIRLAKAWAEVLELQQVGRHDSFFDLGGHSLMAV 12930
Query: 335 TICNKL 340
+ N+L
Sbjct: 12931 RLVNQL 12936
Score = 48.0 bits (109), Expect = 0.001
Identities = 64/292 (21%), Positives = 120/292 (41%), Gaps = 19/292 (6%)
Query: 67 LGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCL 126
+ GE L ++++L R+ LYG +E + ++S +D P+GN
Sbjct: 1879 VAGEALKR-SLVEDLFESTGVQRLCNLYGPSETTTYSSWVAMDREDGFAAHIGKPVGNTR 1937
Query: 127 SETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKE---------ENSIKFIDTGDI 177
Q G+I + LNR + E + + + TGD+
Sbjct: 1938 FYLLDEQQQPVPLGVAGEIYIGGAGVARGYLNRDDLTAERFLLDPFSQQPAARMYRTGDL 1997
Query: 178 GE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW---LQTPLLLIV 233
G + +G + Y GR DD +K G +I L I++ + + P V + L+
Sbjct: 1998 GRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAVHEAVVTAREDIPGDKRLVA 2057
Query: 234 YFSAETLSSQELLDFLKCKLDEK---YW-PDKVIRVDTLPTNAHGKTSKEILVNIYKKSN 289
Y++ + + +D L+ L EK Y P + ++ +P +GK ++ L ++
Sbjct: 2058 YYTLVSGHTSVDIDNLRSHLQEKLPEYMVPAIYVLLEAMPLTPNGKLDRKALPAPDVEAL 2117
Query: 290 ILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ E + +L A+ L + + +FF LGG S LAV++ ++
Sbjct: 2118 SSRGYEAPQGETETQLAAIWQDLLGVARIGRHDNFFELGGHSLLAVSLIGRM 2169
Score = 48.0 bits (109), Expect = 0.001
Identities = 67/297 (22%), Positives = 125/297 (42%), Gaps = 29/297 (9%)
Query: 67 LGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCL 126
+ GE L +++ L K R+ LYG +E + ++S +D P+GN
Sbjct: 9456 VAGEALKR-SLVENLFEKTGVQRLCNLYGPSETTTYSSWVAMDREHGFAAHIGKPVGN-- 9512
Query: 127 SETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---------ENSIKFID 173
T+ ++ ++ G+I + LNR + E + + +
Sbjct: 9513 --TQFYLLDEQQQPVPLGVAGEIYIGGAGVARGYLNRDDLTAERFVKDPFSPQPAARMYR 9570
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT---PL 229
TGD+G + +G + Y GR DD +K G +I L I++ + + P + +
Sbjct: 9571 TGDLGRYLPDGNIEYLGRNDDQVKIRGFRIELGEIDARLAKHPAIHEAVVAAREDVPGDK 9630
Query: 230 LLIVYFSAETLSSQELLDFLKCKLDEK---YW-PDKVIRVDTLPTNAHGKTSKEILVNIY 285
L+ Y++ + +D L+ L E+ Y P + +D LP +GK ++ L
Sbjct: 9631 RLVAYYTLSAGHASVDIDSLRGWLQEQLPAYMIPVAYVLLDALPLTPNGKLDRKALPAPD 9690
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSK--SFFSLGGTSFLAVTICNKL 340
+ I + E + + L A + DL + S+ FF LGG S LA+ + +++
Sbjct: 9691 ADALIRRGYEAPQGET-ETLLAQIWSDLLQLERVSRHDQFFELGGHSLLAMRLISQI 9746
>UniRef50_Q6YK39 Cluster: Bacillomycin D synthetase C; n=4;
Bacillus|Rep: Bacillomycin D synthetase C - Bacillus
subtilis
Length = 2619
Score = 69.7 bits (163), Expect = 3e-10
Identities = 72/326 (22%), Positives = 142/326 (43%), Gaps = 21/326 (6%)
Query: 32 SVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIF 91
+VT TPS F+Q E + + ++ + GGE LN LK+ K K T++
Sbjct: 2015 AVTILNQTPSYFYQLMQEERADPE--SNLNIRKIIFGGEALNP-SFLKDWKLKYPLTQLI 2071
Query: 92 TLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFV----QPHEKNNTMGKIIL 147
+YG+TE + + E+ ++ G + G + + ++ Q + G++ +
Sbjct: 2072 NMYGITETTVHVTYKEITEREIDEGRSNI--GQPIPTLQAYILDEYQHIQVMGIPGELYV 2129
Query: 148 ASKTRKCILLNRKNGNKEE-------NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFG 199
A + LNR E+ K TGD+ + +G + Y GR+D +K G
Sbjct: 2130 AGEGLARGYLNRPELTAEKFVEHPFAAGEKMYKTGDVARWLPDGNIEYLGRIDHQVKIRG 2189
Query: 200 HKINLHSIESTVMQCPRVRSCSCVWLQT--PLLLIVYFSA-ETLSSQELLDFLKCKLDEK 256
++I + +E+ ++Q V+ + ++ L Y S ++L++ +L L KL
Sbjct: 2190 YRIEIGEVEAALLQSESVKEAVVIAIEEEGSKQLCAYLSGDDSLNTAQLKRHLLNKLPAY 2249
Query: 257 YWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYE 316
P ++++ +P A+GK ++ L E + + K+L + L
Sbjct: 2250 MIPAYFVQMEKMPITANGKIERKALPAPEGNRLTGTEYEAPGTLIEKQLAEIWKNILALS 2309
Query: 317 DLQSK-SFFSLGGTSFLAVTICNKLS 341
D K +FF +GG S + + ++++
Sbjct: 2310 DPGIKDNFFDVGGHSLKVLQVIHQIN 2335
Score = 63.3 bits (147), Expect = 2e-08
Identities = 66/301 (21%), Positives = 134/301 (44%), Gaps = 25/301 (8%)
Query: 60 STLKVLALGGEPLNGIKI--LKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
++L+ + GE L + + K + ++ +I LYG TE + S + +
Sbjct: 524 ASLRHVFASGEALKPVHVAGFKHIITSVSQAQIINLYGPTEATIDVSYFDCQTEETYAS- 582
Query: 118 KEVPLGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKEE------ 166
+P+G +S +L++ + + G++ +A LNR E+
Sbjct: 583 --IPIGKPISNIQLYILHADLEHMQPIGVAGELCIAGDGLARGYLNRPELTAEKFVNHPI 640
Query: 167 -NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV- 223
+ + TGD+ + +G + Y GR+D +K G++I + +E Q P ++ +
Sbjct: 641 ASGERIYRTGDLARWLPDGNIEYLGRIDHQVKIRGYRIEIGEVEGAFFQLPVIKEAIVIA 700
Query: 224 -WLQTPLLLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
+ L Y++A+ L++ EL + L +L P ++++ +P +GK ++ L
Sbjct: 701 REIDGETSLCAYYTAQHALTAGELREELSRQLPSYMIPAYFVQLEEMPLTFNGKIDRKSL 760
Query: 282 VNIYKKSNIL-QNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNK 339
+ + N+ N E ++ L K L A+ L E + S FF LGG S ++ + ++
Sbjct: 761 PS--PRENLTGMNYEAPQTELEKILAAVWESVLGLERVGISDHFFELGGDSIKSIQVSSR 818
Query: 340 L 340
L
Sbjct: 819 L 819
>UniRef50_Q0PH95 Cluster: MassB; n=2; Pseudomonas fluorescens|Rep:
MassB - Pseudomonas fluorescens
Length = 4315
Score = 69.7 bits (163), Expect = 3e-10
Identities = 92/360 (25%), Positives = 153/360 (42%), Gaps = 27/360 (7%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDN----DNSVTFWQTTPSKFFQHSNENIKNKILCA 58
EI A +G LLI P L E D V+ TPS F Q I + A
Sbjct: 749 EIWGALMHGGQLLIVPQLVSRSPDECYALLCDAQVSILNQTPSAFRQL----IAAQGNSA 804
Query: 59 RS-TLKVLALGGEPLN-GIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
+S +L+ + GGE L G+ + N T++ +YG+TE + + L+
Sbjct: 805 QSHSLRQVIFGGEALEPGMLKPWYARAVNAGTQLVNMYGITETTVHVTYRALEAADAHLV 864
Query: 117 DKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE------ 166
P+G + + +L+V + +G++ + LNR+ N E
Sbjct: 865 GMS-PIGVRIPDLQLYVLDARREPLPLGVVGELYVGGAGVARGYLNREALNAERFVADPA 923
Query: 167 NSIKFIDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
++ TGD+G + +G+V Y GR DD +K G +I L I++ + VR +
Sbjct: 924 TGLRMYKTGDLGRLLADGSVEYLGRNDDQVKVRGFRIELGEIQAHLATANGVRDAVVIAR 983
Query: 226 QTP---LLLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
+ L+ Y ++ L+ L D L L E P +R+DTLP +GK ++ L
Sbjct: 984 EDQPGDKRLVAYVISDGELNVAALRDHLLRSLAEHMVPSAFVRLDTLPLTTNGKLDRKAL 1043
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + + +S + L L LN + + + +FF LGG S LAV + ++
Sbjct: 1044 PAPHADAVARRAYAAPQSAVETTLARLWQDLLNVDRVGREDNFFELGGHSLLAVKLIERM 1103
Score = 56.0 bits (129), Expect = 4e-06
Identities = 73/304 (24%), Positives = 133/304 (43%), Gaps = 25/304 (8%)
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
A + L++L GGE + + L + R+ YG TE + +A+ E+ + +
Sbjct: 1861 ALAGLRILLCGGERADPAAF-RSLLAQAPALRLVHCYGPTETTTYATTYEV--RALASDA 1917
Query: 118 KEVPLGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKEEN-SIKF 171
VP+G +S T+++V QP T G+I + + LNR E+ + F
Sbjct: 1918 DSVPVGRPISNTQIYVLDAQLQPVPLGIT-GEICIGGEGVAKGYLNRAQLTAEKFVNNPF 1976
Query: 172 ID--------TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
+D TGD+G G + GR DD +K G +I L IE+ + C ++ +
Sbjct: 1977 VDQPGALMYRTGDLGRWSEEGLLECLGRNDDQVKIRGFRIELGEIEARLASCAGIQEVAV 2036
Query: 223 VWLQT---PLLLIVYFS--AETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ + L+ YF+ L ++ L+ +L + P + + +LP +GK
Sbjct: 2037 LAREDVPGDKRLVAYFTWAGADLGIDQVHAHLQGQLPDYMLPSAYMPLASLPLTNNGKLD 2096
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTI 336
++ L + + I + E + + L + L E + + FF LGG S LAV++
Sbjct: 2097 RKALPAPDQAAFISRGYEAPQGEVESLLAQIWQDVLKLERVGRHDHFFELGGHSLLAVSL 2156
Query: 337 CNKL 340
++
Sbjct: 2157 IERM 2160
Score = 56.0 bits (129), Expect = 4e-06
Identities = 46/176 (26%), Positives = 84/176 (47%), Gaps = 3/176 (1%)
Query: 167 NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
N+ + TGD+ + +G + Y GR DD +K G ++ L IES + +R + V +
Sbjct: 3045 NAGRMYRTGDLVRWLPDGNLEYLGRNDDQVKLRGVRVELGEIESRLAALDGIRE-AVVLV 3103
Query: 226 QTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
+ LL + L + L L+ +L E P +++D LP A+GK ++ L
Sbjct: 3104 REGRLLAWFTEQRPLQIETLRAHLQAQLPEALVPVAYMQLDQLPLTANGKLDRKALPQPD 3163
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + + + + + + L L + L E + + FF LGG S LAV++ ++
Sbjct: 3164 QCALLSREYQAPQGDVETTLARLWAEVLQVEQVGRHDHFFELGGHSLLAVSLIERM 3219
Score = 52.4 bits (120), Expect = 4e-05
Identities = 69/290 (23%), Positives = 124/290 (42%), Gaps = 30/290 (10%)
Query: 69 GEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSE 128
GE L G +++ K + ++ LYG TE + V + + D P+G ++
Sbjct: 4006 GEALPG-SLVRRFKQQLPGIGLYNLYGPTEAA--VDVTAWNCARPEVPDN-TPIGKPIAN 4061
Query: 129 TELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE------NSIKFIDTGDIG 178
T L+V + G++ +A LNR E + TGD+G
Sbjct: 4062 TRLYVLDGQLQPVPLGVAGELFIAGVQVARGYLNRPELTAERFLDDPFTPGRMYRTGDLG 4121
Query: 179 E-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLLLIVYFSA 237
+ +GT+ Y GR DD +K G +I L I++ +++ P V+ V + L+ Y++
Sbjct: 4122 RYLPDGTLEYLGRNDDQVKIRGLRIELGEIQARLIEHPAVK--DAVVVARDQRLVAYYTG 4179
Query: 238 ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL-------VNIYKKSNI 290
L L L + P + +D P + +GK ++ L + + + +
Sbjct: 4180 APADIDSLRAQLLQHLPDFMVPALFMHLDAWPLSPNGKLDRKALPAPGMDALQVREYAAP 4239
Query: 291 LQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKL 340
+ E + + L+ EL L + + D +FF LGG S LAV++ +L
Sbjct: 4240 EGDTEVLMAQLWAEL--LKVERVGRHD----NFFELGGHSLLAVSLIGRL 4283
>UniRef50_A1BDX6 Cluster: Amino acid adenylation domain; n=1;
Chlorobium phaeobacteroides DSM 266|Rep: Amino acid
adenylation domain - Chlorobium phaeobacteroides (strain
DSM 266)
Length = 2151
Score = 69.7 bits (163), Expect = 3e-10
Identities = 94/401 (23%), Positives = 174/401 (43%), Gaps = 40/401 (9%)
Query: 3 EILLACTNGASLLI-----APDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC 57
EI + GA+L+I A +T+ LFH + N +T P+ F++ + +
Sbjct: 1291 EIFMTLAVGATLVIRTFNAAISVTDFLFHLEK-NEITVLDL-PTAFWKELVHGVSRTGIK 1348
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELD-LNKVTTG 116
++L+++ +GGE + K K + R+ YG TE S + +E + +N
Sbjct: 1349 IPNSLRLVIIGGEQASVTDFQKWQKVCGGRVRLINTYGPTECSAVSVFSEPEKINCSYDF 1408
Query: 117 DKEVPLGNCLSETELFVQPHE----KNNTMGKIIL--ASKTRKCILLNRKNGNK------ 164
++ +P+G + T L+V G++++ A + + L+ ++
Sbjct: 1409 NRGLPIGRPMDNTTLYVVDEHCCLVPFGMPGELLIGGAGVAKGYLNLSLLTEDRFIDDVF 1468
Query: 165 --EENSIKFIDTGDI-GEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
E + TGDI + +G + + GR D+ +K G +I IES + Q ++
Sbjct: 1469 QESEPKGRLYRTGDIVRSLSDGNLQFLGRKDNQVKIRGFRIEPGEIESVLNQHELIKQSV 1528
Query: 222 CVWL---QTPLLLIVYFSAE--TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
+ L Q L+ YF E LSS EL +L K+ E P + + +P +GK
Sbjct: 1529 VIDLTNDQGETALVGYFVTEKNALSSSELRHYLAQKMPEYMVPSYFVPIKKVPLLPNGKI 1588
Query: 277 SKEIL----VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSF 331
+ L + KK+ + + + K L + + L + + FF LGG S
Sbjct: 1589 DRSALPVPDTVVEKKATYVGPRDETE----KTLVEIWQEVLGVHPIGVTDDFFELGGHSL 1644
Query: 332 LAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQD 372
LAV +C+++ +V K + L + +I + +TIT +
Sbjct: 1645 LAVRLCSQIQ---EKVNKKVTLSGLFQSLTIEKLARTITDE 1682
Score = 38.7 bits (86), Expect = 0.57
Identities = 76/369 (20%), Positives = 148/369 (40%), Gaps = 36/369 (9%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDND----NSVTFWQTTPSKFFQHSNENIKNKILCA 58
EI + G++LLI P+ + H D N +T P +N
Sbjct: 228 EIFSSLLAGSALLIVPESVRIDGHAFMDWLHVNDITSAYLPPMMVADFLEWVERNP---G 284
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
+S ++ L G EP+ +L ++ + I YG TE + A++ +N + +
Sbjct: 285 KSRMRRLLTGVEPIPE-NLLLNIQRCVPQLTIINGYGPTETTICATL--YTVNSASHHHE 341
Query: 119 EVPLGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNK--------- 164
P+G + L + P T G++ + LN+ N+
Sbjct: 342 TTPVGKAVQNMHLHLLDEAGDPVAAGET-GEVYIGGVGVSRGYLNQPELNECLFISDPCY 400
Query: 165 EENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
+E + TGD+ + +G + + GR D +K G++I L IE + +R +
Sbjct: 401 KEEGYRMYRTGDLAVFLPDGELAFVGRKDFQVKYMGYRIELGEIEMVLKSHAAIRDAVVM 460
Query: 224 WLQT-PLL--LIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ P L ++ Y E +S +EL F L P + + +P +GK+
Sbjct: 461 LREDDPGLKKIVAYCVLEISGNVSPKELQLFAGRLLPAYMIPAVFVFLKKIPMTPNGKSD 520
Query: 278 KEILVNIYKKSNILQNVENI---KSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLA 333
+ L K+S + + +S + +++ A+++ L + + FSLG S +A
Sbjct: 521 RNALPPPGKESFLAGKDDGYTAPESVMERDVAAVLSGILGISAIGVDDNLFSLGAHSLMA 580
Query: 334 VTICNKLSL 342
+C+++ +
Sbjct: 581 TRLCSQIRM 589
>UniRef50_P40806 Cluster: Putative polyketide synthase pksJ; n=9;
Bacteria|Rep: Putative polyketide synthase pksJ -
Bacillus subtilis
Length = 5045
Score = 69.7 bits (163), Expect = 3e-10
Identities = 69/297 (23%), Positives = 136/297 (45%), Gaps = 28/297 (9%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
++K+L GGE L + LK + + + ++G TE + W++V +++
Sbjct: 1416 SVKILC-GGEALP--ETLKRY-FLDTGSEAWNMFGPTETTIWSAVQRINVEC-----SHA 1466
Query: 121 PLGNCLSETELFVQPHE----KNNTMGKIILASK-------TRKCILLNRKNGNKEENSI 169
+G ++ T++++ + G++ +A ++ + +R N E
Sbjct: 1467 TIGRPIANTQIYITDSQLAPVPAGVPGELCIAGDGVAKGYYKKEELTDSRFIDNPFEPGS 1526
Query: 170 KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP 228
K TGD+ + G + Y GR+D+ +K G +I L IES + + P + CV +
Sbjct: 1527 KLYRTGDMARWLTGGRIEYIGRIDNQVKIRGFRIELGDIESRLSEHPGI--LECVVVADM 1584
Query: 229 LLLIVYFSAE----TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
L Y++A+ +L+++EL F+K L P I++D +P +GK + L NI
Sbjct: 1585 DNLAAYYTAKHANASLTARELRHFVKNALPAYMVPSYFIQLDHMPLTPNGKIDRNSLKNI 1644
Query: 285 YKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
L+ + + + + + L D++ FF +GG S LAVT+ +++
Sbjct: 1645 DLSGEQLKQRQTSPKNIQDTVFTIWQEVLKTSDIEWDDGFFDVGGDSLLAVTVADRI 1701
Score = 38.3 bits (85), Expect = 0.76
Identities = 18/49 (36%), Positives = 27/49 (55%)
Query: 171 FIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRS 219
+ +TGD+G +RNG + GR D I G H+IES V + P + +
Sbjct: 430 WFETGDLGFLRNGRLTITGRTKDAIIINGINYYSHAIESAVEELPEIET 478
>UniRef50_O31782 Cluster: Polyketide synthase of type I; n=2; Bacillus
subtilis|Rep: Polyketide synthase of type I - Bacillus
subtilis
Length = 5488
Score = 69.3 bits (162), Expect = 4e-10
Identities = 82/316 (25%), Positives = 133/316 (42%), Gaps = 32/316 (10%)
Query: 53 NKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNK 112
NK LK + + GE + + K + N R+ +YG TE S +A A K
Sbjct: 725 NKRFTEDGPLKYMMVAGEAFPKVLVKKAVSLFTN-CRVENIYGPTEASIYA--AYFGCGK 781
Query: 113 VTTGDKEVPLGNCLSETELF-VQPHEKNNTMGK---IILASK-------TRKCILLNRKN 161
P+G +S T+++ V H K +GK + +A + + +
Sbjct: 782 GDIASHHTPIGKPVSNTKIYIVDQHLKPVPIGKPGELCIAGAGLARGYFKKPGLTAEKFI 841
Query: 162 GNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSC 220
N E+ K +GD + +G + Y GR+D +K G ++ L +IE+ + + P +
Sbjct: 842 DNPFESGTKLYKSGDSARWLPDGNIEYLGRIDSQVKIRGFRVELGAIETKLGEFPGILDQ 901
Query: 221 SCV--WLQTPLLLIVYFSAE----TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
+ V L+ L Y++ E + + ++L LK L E P IR+D LP + G
Sbjct: 902 AVVVKQLEGHQQLAAYYTEESGHASANPKDLRLHLKSSLPEYMIPSHFIRLDELPLSPSG 961
Query: 275 KTS------KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGG 328
K + +EI+ N +K N LQ E L + L ED FF GG
Sbjct: 962 KVNRKELEKREIVFN-RRKPNHLQLTEIEDQVLRIWEETLKVSGFGPED----GFFDAGG 1016
Query: 329 TSFLAVTICNKLSLTF 344
S LAV + ++ F
Sbjct: 1017 DSLLAVAVAERIKKEF 1032
>UniRef50_A3IP47 Cluster: Peptide synthetase; n=2; Cyanobacteria|Rep:
Peptide synthetase - Cyanothece sp. CCY 0110
Length = 2942
Score = 69.3 bits (162), Expect = 4e-10
Identities = 96/402 (23%), Positives = 171/402 (42%), Gaps = 46/402 (11%)
Query: 2 VEILLACTNGASLLIAPDLT----EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC 57
+E+ L G ++L+A T E L H ++ T Q TP+ + N K
Sbjct: 734 LELYLPLIRGGTILLASQETASDGEKLAHLLQNSCTTIMQATPATWRMLIAANWTGK--- 790
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASV-AELDLNKVTTG 116
S LK+L GGE L L E H++++ ++ +YG TE + W+SV L+K
Sbjct: 791 --SNLKILC-GGEALP--TSLAEQLHQSSR-ELWNVYGPTETTIWSSVYCVKSLSKTLDI 844
Query: 117 DKEVP-LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE----- 166
K V +G+ + T++++ G++ + LNR E+
Sbjct: 845 AKTVQSIGHPIDNTQMYLLDSNLEPVPIGVAGELYIGGDGLARGYLNRPELTAEKFIPNP 904
Query: 167 ----NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
+ TGD+ + +G + Y GR+D +K G +I L IES + P V+
Sbjct: 905 FDPTGKTRLYKTGDLCRYLPDGNIEYIGRIDHQVKIRGFRIELGEIESLLTSHPEVQESV 964
Query: 222 CVWLQTP---LLLIVYFSAETLS----SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
+ + L+ Y + + +Q L D+LK +L + P + ++ LP +G
Sbjct: 965 VIAREDQPGNKRLVAYIVTQEVGEDSLNQTLRDYLKGQLPDYMIPSAFVFIEKLPLTPNG 1024
Query: 275 KTSKEILVNIYKKSNILQNVENIKSYLFKE--LKALVNKDLNYEDLQ-SKSFFSLGGTSF 331
K ++ L + + + + +E L + ++ L E + + +FF LGG S
Sbjct: 1025 KIDRKALP--APDFSAMAQADFVAPSTDREQILAQVWSEVLRIEKISINSNFFELGGDSI 1082
Query: 332 LAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQDT 373
L + I + + G I P L +++I + L T+ Q T
Sbjct: 1083 LTIQIVARAK----QAGLRISPKQLFEHQTIAE-LATVAQQT 1119
Score = 56.0 bits (129), Expect = 4e-06
Identities = 73/288 (25%), Positives = 120/288 (41%), Gaps = 37/288 (12%)
Query: 90 IFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKI 145
+ LYG TE + S + N K+VP+G ++ T+L++ +G++
Sbjct: 2350 LHNLYGPTEAAIDVSYWQCQPNSTL---KKVPIGRPVANTQLYILNQALKPVPVGAVGEL 2406
Query: 146 ILASKTRKCILLNRKNGNKE---------ENSIKFIDTGDIGE-IRNGTVFYRGRVDDTI 195
+ LNR E + + TGD+ + +G + Y GR+D +
Sbjct: 2407 HIGGVQVGKGYLNRPQLTAEKFINDPFSQDAEARLYKTGDLCRYLPDGNIEYLGRIDHQV 2466
Query: 196 KRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL---LLIVY-------------FSAET 239
K G +I L IE + Q P VR + Q L+ Y + E
Sbjct: 2467 KIRGFRIELGEIEGVLTQHPDVREVVVIVRQDHFDNKQLVAYVVSPLFPDDDEQVMTIEG 2526
Query: 240 LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV--NIYKKSNILQNVENI 297
SQ L D+LK KL + P + + +LP +GK + L + +S+ Q
Sbjct: 2527 KLSQALRDYLKDKLPDYMIPFAFVLLPSLPLTPNGKIDRRSLPIPTAFTRSS-QQRFIPP 2585
Query: 298 KSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKLSLTF 344
+ L ++L + + LN + + SFF LGG S LAV + +K+S F
Sbjct: 2586 RDGLEQQLVEIWEEILNLAPISVQDSFFELGGHSLLAVRLISKISEVF 2633
>UniRef50_Q464U3 Cluster: Putative uncharacterized protein; n=2;
Methanosarcina barkeri str. Fusaro|Rep: Putative
uncharacterized protein - Methanosarcina barkeri (strain
Fusaro / DSM 804)
Length = 1682
Score = 69.3 bits (162), Expect = 4e-10
Identities = 67/270 (24%), Positives = 117/270 (43%), Gaps = 18/270 (6%)
Query: 490 VGTYDGTVICFLLENCSVIWQINVGSMIKSK-ATYCKGVLYIASYDGNIRCIDILTSTIK 548
+G+YD + L + ++ W G+ I S A G +YI SYD NI ++ T+K
Sbjct: 208 IGSYDNKLYA-LNSDGTLKWSYTTGNRISSSPAIGVDGTVYIGSYDKNIYALNP-DGTLK 265
Query: 549 ETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDN 608
+ + + IS + + + G+ L+ + T+ W+ G C
Sbjct: 266 WS-YTTGNRISCSPAIGTDGTVYIGSNDKYLYGLNPDG-TLKWK-YYAGAQLQCTPAIGT 322
Query: 609 DKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNN-V 667
D + +++ +K W+YNG +G S + +YFG DN +
Sbjct: 323 DGTIYIESGYRDVYALNPNGTLK-WSYNGGEGVAGSPAIGAD-----GTIYFGTTDNKKI 376
Query: 668 YSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLP 727
Y++N + +L W + S+P I D I S+D KL+ ++S+ GT+ Y +
Sbjct: 377 YALNP---EGTLRWSYTAGGNLGSSPAIGADGTIYIGSSDNKLYALNSD-GTLKWTYAIT 432
Query: 728 GETFSSPII-CDDHVFIGCRNDLLYSLKID 756
G SP I D ++ G ++ LY+L D
Sbjct: 433 GNQIGSPAIGADGTIYFGSNDNKLYALNPD 462
Score = 48.8 bits (111), Expect = 5e-04
Identities = 62/296 (20%), Positives = 125/296 (42%), Gaps = 23/296 (7%)
Query: 417 VQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPIL 476
++W++ TG + +SPA+ +V +GS+ I +N + G ++ +RI
Sbjct: 224 LKWSYTTGNRISSSPAIGVDGTVY---IGSYDKNIYALNPD-GTLKWSYTTGNRISCSPA 279
Query: 477 CVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIK-SKATYCKGVLYIASYDG 535
D V +G+ D + L + ++ W+ G+ ++ + A G +YI S
Sbjct: 280 IGTDGTV-----YIGSND-KYLYGLNPDGTLKWKYYAGAQLQCTPAIGTDGTIYIESGYR 333
Query: 536 NIRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSL 595
++ ++ T+K + + + ++ + + I FGT T+ W +
Sbjct: 334 DVYALNP-NGTLKWSYN-GGEGVAGSPAIGADGTIYFGTTDNKKIYALNPEGTLRWSYTA 391
Query: 596 KGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFK 655
G + + P + D + + +++ + +K WTY GN S +
Sbjct: 392 GGNLGSSPAI-GADGTIYIGSSDNKLYALNSDGTLK-WTY-AITGNQIGSPAIGADGT-- 446
Query: 656 WQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLW 711
+YFG +DN +Y++N +L W V + + S+P I D + S D KL+
Sbjct: 447 --IYFGSNDNKLYALNPDG---TLKWTYAVENQIVSSPAIGADGTLYIGSLDKKLY 497
Score = 46.8 bits (106), Expect = 0.002
Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 10/126 (7%)
Query: 632 IWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYS 691
IWTY K I SS + +Y G +DN +Y++N +L W + + S
Sbjct: 185 IWTYTATK-QISSSPAIGTDGT----IYIGSYDNKLYALNSDG---TLKWSYTTGNRISS 236
Query: 692 TPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPII-CDDHVFIGCRNDLL 750
+P I D + S D ++ ++ + GT+ Y SP I D V+IG + L
Sbjct: 237 SPAIGVDGTVYIGSYDKNIYALNPD-GTLKWSYTTGNRISCSPAIGTDGTVYIGSNDKYL 295
Query: 751 YSLKID 756
Y L D
Sbjct: 296 YGLNPD 301
>UniRef50_Q4C9F4 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Crocosphaera watsonii WH 8501|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Crocosphaera watsonii
Length = 1569
Score = 68.9 bits (161), Expect = 5e-10
Identities = 78/329 (23%), Positives = 142/329 (43%), Gaps = 31/329 (9%)
Query: 65 LALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGN 124
L +GGE L+ K L + K+ KTR+ YG TE V ++ + + VP+G
Sbjct: 776 LIIGGEALSS-KSLTFWQEKSPKTRLINEYGPTETVVGCCVYQVPPQ--VSHSENVPIGR 832
Query: 125 CLSETELFVQPHEKNNTM----GKIILASKTRKCILLNRKNGNKEE-------------N 167
++ TE+++ T G++ + NR + E +
Sbjct: 833 PITNTEIYILDQYLQPTPIGVPGELYIGGLGVARGYFNRPDLTAERFIPHPFTRRQPTPS 892
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
S + TGD+ + +GT+ Y GR+DD +K G ++ L IE + Q P+V+ V +
Sbjct: 893 SSRLYKTGDLARYLSDGTIEYLGRIDDQVKIRGFRVELGEIEGILRQHPQVKEAIAVVQE 952
Query: 227 TP---LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT-SKEILV 282
L+ Y AE+ +EL F KL P + +D+ P +GK K++
Sbjct: 953 DNNKIPRLVAYVVAES-EIEELRQFTSDKLPGYMVPTLFLTMDSFPLTVNGKIHRKKLPA 1011
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLS 341
+ + N+ + + ++ + L + L ++ +FF LGG S L + I + +
Sbjct: 1012 ADFFQRNVKKELIASRTQQEEALTEIWRDVLGKMEVGIYDNFFELGGDSILGLQIIARAN 1071
Query: 342 LTFPEVGKHILPHLLSHNKSIGDVLKTIT 370
+VG + P L +++I ++ T
Sbjct: 1072 ----QVGLQLTPRQLFQHQNIAELASVAT 1096
>UniRef50_Q4C3C3 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Crocosphaera watsonii WH 8501|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Crocosphaera watsonii
Length = 1518
Score = 68.9 bits (161), Expect = 5e-10
Identities = 75/323 (23%), Positives = 142/323 (43%), Gaps = 34/323 (10%)
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
K+L LGGE L+ ++K+++ RI YG TE + ++ + VP+
Sbjct: 718 KLLILGGESLSW-SLVKQIQELQPNCRILNHYGPTETTIGVLTFKVPQEEHQYA-ATVPI 775
Query: 123 GNCLSETELFVQPHEKNN----TMGKIILASKTRKCILLNRKNGNKE-------ENSIKF 171
G L T++++ T G+I + NR +E + S +
Sbjct: 776 GRPLDNTQIYLLDEYLQPVPLLTPGEIYIGGANLSRGYYNRPELTEERFIINPFDQSTRL 835
Query: 172 IDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL- 229
TGD+G + +G++ + GR D +K G +I L IE+ + Q P V+ +
Sbjct: 836 YKTGDVGRYLPDGSIEFLGRSDRQVKIRGFRIELGEIEAVLSQHPSVKQAVVTVPKDEKG 895
Query: 230 --LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL-----V 282
L+ Y + ++ L DF++ +L + P + + + T+P A+GK + L
Sbjct: 896 NQRLVAYVVLGSHNTDHLQDFMRIRLPQYMVPHRFVTLKTIPVTANGKIDYKALPAPKEE 955
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSL 342
N Y N Q E + ++ E+ L + ++ +D +FF LGG S +++ + +K +
Sbjct: 956 NDYVAPNTPQ--EETLATIWAEILGL--ERVSIDD----NFFQLGGDSIISIQVISKAN- 1006
Query: 343 TFPEVGKHILPHLLSHNKSIGDV 365
++G + P L +I +
Sbjct: 1007 ---QMGLQLTPQQLFEYPTIAQL 1026
>UniRef50_Q1Q044 Cluster: Similar to beta-propeller protein YxaL;
n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to
beta-propeller protein YxaL - Candidatus Kuenenia
stuttgartiensis
Length = 381
Score = 68.9 bits (161), Expect = 5e-10
Identities = 63/250 (25%), Positives = 111/250 (44%), Gaps = 16/250 (6%)
Query: 509 WQINVGSMIKSKATYCK-GVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKN 567
W ++ I S K G +YI S DGN+ I + + S+ I A + +N
Sbjct: 67 WYVSSAGEIWSSPVISKEGNIYITSTDGNLLAIAPEGNVL--WAFKSEDEIFATPAVGEN 124
Query: 568 EFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVE 627
I FG + G + K + W+ + I + PV+ D + + F +G ++ +
Sbjct: 125 GDIYFGAVDGNLYTVDAYGK-MKWKFNTNTSIHSSPVI-DAEGNIYFGAYDGNLYAVDAQ 182
Query: 628 KGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSS 687
G +W + I SS + + N +Y G D ++Y++ L WK R
Sbjct: 183 -GKLLWKFKTGSAIIASSPAIGQNN----TIYVGSWDKHLYAIKRDG---GLMWKFRTEG 234
Query: 688 PVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDD-HVFIGCR 746
+ ++P I N +I A GKL+ ++ + GT+ + L T SSP++C D + IG
Sbjct: 235 KIDASPAIGN-SVIYIADVTGKLYAVNLD-GTLKWGFDLDSRTHSSPVLCSDGTICIGTH 292
Query: 747 NDLLYSLKID 756
+ + ++K D
Sbjct: 293 DGGVCAVKND 302
Score = 68.9 bits (161), Expect = 5e-10
Identities = 57/247 (23%), Positives = 111/247 (44%), Gaps = 16/247 (6%)
Query: 509 WQINVGSMIKSKATY-CKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKN 567
W+ N + I S +G +Y +YDGN+ +D + + I++ + +N
Sbjct: 147 WKFNTNTSIHSSPVIDAEGNIYFGAYDGNLYAVDAQGKLLWK-FKTGSAIIASSPAIGQN 205
Query: 568 EFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVE 627
I G+ + ++W+ +G I A P + ++ Y+ A+V G+++ ++
Sbjct: 206 NTIYVGSWDKHLYAIK-RDGGLMWKFRTEGKIDASPAIGNSVIYI--ADVTGKLYAVNLD 262
Query: 628 KGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSS 687
+K W ++ S + + + G HD V +V SL WK + +
Sbjct: 263 GTLK-WGFDLDSRTHSSPVLCSD-----GTICIGTHDGGVCAVKNDG---SLKWKFKTNK 313
Query: 688 PVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPII-CDDHVFIGCR 746
PV +TPT+ +I S DG L+ I+ + G++ + SSP I ++++IGC
Sbjct: 314 PVTATPTVDAKDIIYVGSWDGNLYAINKD-GSLKWKLDFKNSLLSSPAIDSRNNIYIGCA 372
Query: 747 NDLLYSL 753
+ LY++
Sbjct: 373 DWRLYAV 379
Score = 53.2 bits (122), Expect = 2e-05
Identities = 42/157 (26%), Positives = 80/157 (50%), Gaps = 15/157 (9%)
Query: 417 VQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRI-EAPI 475
+ W F T +DASPA+ SV+Y + +GK+ +N + G ++ L SR +P+
Sbjct: 226 LMWKFRTEGKIDASPAI--GNSVIY--IADVTGKLYAVNLD-GTLKWGFDLDSRTHSSPV 280
Query: 476 LCVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATY-CKGVLYIASYD 534
LC D + C +GT+DG V C + + S+ W+ + + T K ++Y+ S+D
Sbjct: 281 LC-SDGTI---C--IGTHDGGV-CAVKNDGSLKWKFKTNKPVTATPTVDAKDIIYVGSWD 333
Query: 535 GNIRCIDILTSTIKETVHVSDQAISADLVLAKNEFIL 571
GN+ I+ ++K + + +S+ + ++N +
Sbjct: 334 GNLYAIN-KDGSLKWKLDFKNSLLSSPAIDSRNNIYI 369
Score = 49.6 bits (113), Expect = 3e-04
Identities = 40/170 (23%), Positives = 82/170 (48%), Gaps = 13/170 (7%)
Query: 589 IIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCV 648
I W S G I++ PV+ + + +G + E + +W + ++ IF++ V
Sbjct: 65 IKWYVSSAGEIWSSPVI-SKEGNIYITSTDGNLLAIAPEGNV-LWAFK-SEDEIFATPAV 121
Query: 649 KEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDG 708
E +YFG D N+Y+V+ + WK ++ ++S+P I + I + DG
Sbjct: 122 GE----NGDIYFGAVDGNLYTVDAYG---KMKWKFNTNTSIHSSPVIDAEGNIYFGAYDG 174
Query: 709 KLWVIHSELGTVTAQYQLPGETF-SSPIICDDH-VFIGCRNDLLYSLKID 756
L+ + ++ G + +++ SSP I ++ +++G + LY++K D
Sbjct: 175 NLYAVDAQ-GKLLWKFKTGSAIIASSPAIGQNNTIYVGSWDKHLYAIKRD 223
Score = 36.7 bits (81), Expect = 2.3
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 675 FQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSP 734
F+ + W + ++S+P I + I STDG L I E G V ++ E F++P
Sbjct: 61 FKNEIKWYVSSAGEIWSSPVISKEGNIYITSTDGNLLAIAPE-GNVLWAFKSEDEIFATP 119
Query: 735 IICDD-HVFIGCRNDLLYSL 753
+ ++ ++ G + LY++
Sbjct: 120 AVGENGDIYFGAVDGNLYTV 139
>UniRef50_Q12IB7 Cluster: Amino acid adenylation; n=1; Shewanella
denitrificans OS217|Rep: Amino acid adenylation -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 2457
Score = 68.9 bits (161), Expect = 5e-10
Identities = 73/301 (24%), Positives = 124/301 (41%), Gaps = 22/301 (7%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S LK + L GEPL G + + N + LYG +E + L V ++
Sbjct: 291 SHLKHILLAGEPLFGRDANRWITLVGNDIELVNLYGPSETTLAKLFYRLK-GPVEQANQM 349
Query: 120 VPLGNCLSETELFVQPHE---KNNTMGKIILASKTRKCILLNR---------KNGNKEEN 167
+P+GN ++ T + + + + +G+I + + R LN +N +N
Sbjct: 350 IPIGNPIANTAVLILANNTLCRVGDIGEIYIKTPFRSKGYLNDQPLTDLSFIQNPLNPDN 409
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL- 225
TGD+G + N +V GR+D +K G ++ L+ IE + + C
Sbjct: 410 EDIIYKTGDLGRYLENHSVEVLGRLDRQVKLNGIRVELNDIEGHIHNLSAIDQCFINLYK 469
Query: 226 ---QTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
Q+ L+ Y + +S+ E+ D L KL P +I++ + P +GK K+ L
Sbjct: 470 DEDQSSKLVCYYTCHQDISTNEIKDLLADKLSTNLIPSMMIKLSSFPLMLNGKVDKKALP 529
Query: 283 NIYKKSNILQNVENIKSYLFKE--LKALVNKDLNYEDLQS-KSFFSLGGTSFLAVTICNK 339
N N N+E + E L + L L FF LGGTS + + +
Sbjct: 530 NPATYFNDF-NIEEEQDLSPTELILSEIWRTSLGAASLSKYHHFFDLGGTSLAVMKVLGE 588
Query: 340 L 340
+
Sbjct: 589 M 589
Score = 50.0 bits (114), Expect = 2e-04
Identities = 66/291 (22%), Positives = 119/291 (40%), Gaps = 25/291 (8%)
Query: 86 NKTRIFTLYGVTEMSCWASVAELDLNK---VTTGDKEVPLGNCLSETELFV-QPHEKN-- 139
+K R YG TE + ASV E+ + +K +P+G +S L V H +
Sbjct: 1371 DKVRYINAYGPTETTVCASVFEVSATAWADLKQNNKPIPIGKAISNLRLDVLDSHLQQLP 1430
Query: 140 -NTMGKIILASKTRKCILLNRKNGNKE---EN----SIKFIDTGDIGE-IRNGTVFYRGR 190
G++ ++ LN+ K+ +N + TGD+ + +G + + GR
Sbjct: 1431 AGISGELYISGLGVSHGYLNQTGLTKQCFTQNPHMPELPMYKTGDLARRLADGNIEFLGR 1490
Query: 191 VDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV--WLQTPLLLIVYFSAETLSSQELLDF 248
DD +K G++I IE ++Q ++ + + L Y+ +
Sbjct: 1491 KDDQVKIRGYRIEPMEIEYQLLQLEQIADARVLVNGKASQQYLSAYYIGVADDESIIRQA 1550
Query: 249 LKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI--YKKSNI--LQNVENIKSYLFKE 304
L L + P + T P + K L + +K I L N ++I++ +
Sbjct: 1551 LSSTLPKYMIPSTFTALRTFPMTPNNKVDSSALRQLSEQQKGGIISLPNSKDIEASITSI 1610
Query: 305 LKALVNKDLNYEDLQSKSFFSLGGTSFLAV-TICNKLSLTFPEVGKHILPH 354
K ++N +N+ + Q++SF LGG S A+ T+ L HIL +
Sbjct: 1611 WKRILN--INHIN-QTQSFIELGGDSIKAIQTVAELKKLGLKIKANHILQY 1658
>UniRef50_A7BRU4 Cluster: Non-ribosomal peptide synthetase; n=1;
Beggiatoa sp. PS|Rep: Non-ribosomal peptide synthetase -
Beggiatoa sp. PS
Length = 1010
Score = 68.9 bits (161), Expect = 5e-10
Identities = 67/296 (22%), Positives = 133/296 (44%), Gaps = 21/296 (7%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
++L+V+ GGE + + + N K ++ YG TE + ++ + ++
Sbjct: 272 ASLRVVLFGGETAD-VDCVNHFATCNPKVQLINGYGPTENTTFSMAYRIQ----GVQQQD 326
Query: 120 VPLGNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKN-------GNKEENS 168
VP+G ++ ++ ++ E +G+I +A + LNR + N +
Sbjct: 327 VPIGKPIANSQAYIYDREGCQCPVGQIGEICVAGEGLSRGYLNRPDLTVLKFVQNPDMPG 386
Query: 169 IKFIDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV-W-- 224
TGD+G RNG + + GR D+ +K GH+I L IE+T+ Q +R W
Sbjct: 387 TLMYRTGDLGYWDRNGNIHFSGRSDNQVKLRGHRIELGEIENTLQQLRGIREIVVKDWGV 446
Query: 225 LQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
L + Y +A LSS + FL+ +L P K + ++ +P + +GK ++ L+
Sbjct: 447 GGDKYLCVYYTAARELSSNAIRIFLQERLPAYMVPSKFVWLEEMPVSWNGKVDRQALLIP 506
Query: 285 YKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKL 340
+ + V ++ L ++ + + + + F +GG S LA+ + ++L
Sbjct: 507 SQVALYDPPVTALERLLVAIWSEVLGQKSDCVGVHDR-FDEIGGNSLLAMQVMSRL 561
>UniRef50_A1D5S0 Cluster: Nonribosomal peptide synthase, putative;
n=1; Neosartorya fischeri NRRL 181|Rep: Nonribosomal
peptide synthase, putative - Neosartorya fischeri
(strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 1028
Score = 68.9 bits (161), Expect = 5e-10
Identities = 69/272 (25%), Positives = 118/272 (43%), Gaps = 30/272 (11%)
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHE-KNNTMGKIIL 147
++FT YG +E +C S EL D+EVP G + ++ + E K + G++++
Sbjct: 302 KVFTTYGPSETTCVISFGELH------PDQEVPFGELIPGVKVVLVNEEMKESNYGEVLI 355
Query: 148 ASKTRKCILLNRKNGNKEE----NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKI 202
+ LN ++ N +F TGD+ +G + + GR D +K G I
Sbjct: 356 SGPGLAAGYLNNPTLTAKKFIKWNGERFYRTGDLARRTEDGQLIWAGRADSLVKNRGFLI 415
Query: 203 NLHS-IESTVMQCPRVRSCSCVWLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDK 261
NL + +E + P+V V Q L+ T+ +EL F++ + D PD
Sbjct: 416 NLETEVEPAMQAYPQVNLA--VAFQWRDRLVGCVQPSTVDVEELRKFMQSRADPFVIPDM 473
Query: 262 VIRVDTLPTNAHGKTSKEIL-VNIYKK---------SNILQNVENIKSYLFKEL---KAL 308
+ +D+ P N + KT + L + +K L + + +Y L + L
Sbjct: 474 IFAMDSFPLNVNSKTDRLALQAQLDEKLGQDDDPVEGASLLETDRLTAYDALRLAFSRCL 533
Query: 309 VNKDLNYEDLQSKSFFSLGGTSFLAVTICNKL 340
N+ N + +S SF LGG S A+ + N L
Sbjct: 534 QNRFRNMD--RSSSFTRLGGNSLAAIQVSNFL 563
>UniRef50_Q12IB9 Cluster: Amino acid adenylation; n=3; cellular
organisms|Rep: Amino acid adenylation - Shewanella
denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
Length = 3718
Score = 68.5 bits (160), Expect = 6e-10
Identities = 89/348 (25%), Positives = 149/348 (42%), Gaps = 32/348 (9%)
Query: 19 DLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKIL 78
D++ VL H +TF + TPS F N + L TL+++ LGGE L +
Sbjct: 2885 DISFVL-HYIAQQHLTFIKMTPSLFQVLVNHHDFTPALGL--TLRLMILGGEKLRADDVA 2941
Query: 79 KELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEK 138
L+ +T YG TE + E + + +G ++ ++++ ++
Sbjct: 2942 NYLQCFK-ETVFVNHYGPTEATIGCITREFNAATFEQYRHNMSIGQPIANCKVYIL--DQ 2998
Query: 139 NNTM------GKIILASKTRKCILLNRKNGNKEENSIKFID-----------TGDIGEIR 181
NN + G+I + C+ L N + E + KFI TGD G I
Sbjct: 2999 NNIVVADGEHGEICIEGD---CLALGYLNHDDLEQA-KFITLPLSPDKRVYKTGDCGVII 3054
Query: 182 NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL---LLIVYFSAE 238
N V GR DD +K G+++ L + + + Q P+V+ + + Q L+ Y S E
Sbjct: 3055 NNEVHINGRFDDQVKIRGYRVELGEVINVLEQHPKVQRAAVINKQNQSGNELVAYYQSRE 3114
Query: 239 TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK-SNILQNVENI 297
++ EL F+ L P + V PTNA+GK L+N ++K S+ + +
Sbjct: 3115 PVTVTELRKFMSEHLPSYTCPSHYLEVVHFPTNANGKLDINKLLNSHEKTSSGITTTTDK 3174
Query: 298 KSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLSLTF 344
S + + + + L + + FF+LGG S A+ I LS F
Sbjct: 3175 LSASQQVIFDVWQQHLQIPSMGLTDDFFALGGHSLKAMLISAALSQKF 3222
>UniRef50_Q110E8 Cluster: Amino acid adenylation domain; n=1;
Trichodesmium erythraeum IMS101|Rep: Amino acid
adenylation domain - Trichodesmium erythraeum (strain
IMS101)
Length = 1331
Score = 68.5 bits (160), Expect = 6e-10
Identities = 61/222 (27%), Positives = 109/222 (49%), Gaps = 20/222 (9%)
Query: 162 GNKEEN-SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRS 219
GNKE+ + TGD+ + +G + + GR+D+ +K G +I + IE+T+ Q P V+
Sbjct: 837 GNKEQGIGNRLYKTGDLARYLSDGNIEFLGRIDNQVKIRGFRIEIGEIETTLSQHPIVKE 896
Query: 220 CSCVWLQTP---LLLIVYFSAETLSSQ----ELLDFLKCKLDEKYWPDKVIRVDTLPTNA 272
+ + LL+ Y ET +Q +L +LK KL E P + + LP
Sbjct: 897 TVVLLREDKPGNKLLVAYIVPETEGAQNVVPQLKQYLKEKLAEYMVPSAFVVLSKLPLTP 956
Query: 273 HGKTSKEIL----VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKS-FFSLG 327
GK ++ L ++ + +S+ N + + ++L + ++ LN + KS FF LG
Sbjct: 957 SGKVNRRALPAPDISSFSQSD---NFVAPRDRIEQQLAQMWSEILNIHPVGVKSNFFELG 1013
Query: 328 GTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTI 369
G S LA+ + K+ +F G+ + L N++I D+ + I
Sbjct: 1014 GHSLLAINLMAKIQESF---GQQLPLSTLFTNRTIEDLGRLI 1052
>UniRef50_Q3IRQ8 Cluster: Predicted cell surface protein/
lipoprotein; n=1; Natronomonas pharaonis DSM 2160|Rep:
Predicted cell surface protein/ lipoprotein -
Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)
Length = 389
Score = 68.5 bits (160), Expect = 6e-10
Identities = 45/181 (24%), Positives = 83/181 (45%), Gaps = 11/181 (6%)
Query: 573 GTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKI 632
GT G L + W S GP+ PV+ +D V +G I+ + G ++
Sbjct: 95 GTADGEVYALDTHVGAERWSFSADGPVSTTPVV--DDGLVAVGSSDGHIYGIDADDGTEL 152
Query: 633 WTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYST 692
W ++ A + SS + + +Y G N Y+++ TN + LHW+ V ++
Sbjct: 153 WRFDTAV-RVDSSPAIDDR-----YVYAGSVSNAAYAIDRTNGE--LHWRFDADGSVLAS 204
Query: 693 PTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYS 752
P + D+ + ASTD ++ I + G Q+ GE +P + D +++G R+ +Y+
Sbjct: 205 PAV-GDETVYVASTDHNVYAIDPDSGEADWQFTTGGEISVAPTLVGDRLYVGSRDSSVYA 263
Query: 753 L 753
+
Sbjct: 264 I 264
Score = 64.5 bits (150), Expect = 1e-08
Identities = 59/269 (21%), Positives = 114/269 (42%), Gaps = 17/269 (6%)
Query: 491 GTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKET 550
GT DG V + W + + + G++ + S DG+I ID T
Sbjct: 95 GTADGEVYALDTHVGAERWSFSADGPVSTTPVVDDGLVAVGSSDGHIYGIDADDGT---E 151
Query: 551 VHVSDQAISADLVLAKNE-FILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDND 609
+ D A+ D A ++ ++ G++S + + W+ G + A P + D
Sbjct: 152 LWRFDTAVRVDSSPAIDDRYVYAGSVSNAAYAIDRTNGELHWRFDADGSVLASPAVGDET 211
Query: 610 KYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYS 669
YV A + ++ + G W + G I S+ + ++Y G D++VY+
Sbjct: 212 VYV--ASTDHNVYAIDPDSGEADWQFTTG-GEI--SVAPTLVGD---RLYVGSRDSSVYA 263
Query: 670 VNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQ--LP 727
++ + + W + + V S+P + D+L + A+ D L+ + + ++ P
Sbjct: 264 IDTGSGEG--RWSFGLEAAVASSPAVLGDRLFVGAA-DHNLYALGIGDDSPEGLWRSPTP 320
Query: 728 GETFSSPIICDDHVFIGCRNDLLYSLKID 756
G +P + DDHVF G R+ + +L+ D
Sbjct: 321 GAAVGNPAVTDDHVFFGGRDGAVRALRTD 349
Score = 63.3 bits (147), Expect = 2e-08
Identities = 52/247 (21%), Positives = 105/247 (42%), Gaps = 13/247 (5%)
Query: 509 WQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKNE 568
WQ +VG + + + LY + DG + +D + + +D +S V+ +
Sbjct: 73 WQFDVGGAVIGGPVFDENTLYAGTADGEVYALDTHVGAERWSFS-ADGPVSTTPVV-DDG 130
Query: 569 FILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEK 628
+ G+ G + + T +W+ + + P + +D+YV V+ +
Sbjct: 131 LVAVGSSDGHIYGIDADDGTELWRFDTAVRVDSSPAI--DDRYVYAGSVSNAAYAIDRTN 188
Query: 629 GIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSP 688
G W ++ A G++ +S V + +Y D+NVY+++ + + W+
Sbjct: 189 GELHWRFD-ADGSVLASPAVGDET-----VYVASTDHNVYAIDPDSGEAD--WQFTTGGE 240
Query: 689 VYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRND 748
+ PT+ D+L + S D ++ I + G + L SSP + D +F+G +
Sbjct: 241 ISVAPTLVGDRLYV-GSRDSSVYAIDTGSGEGRWSFGLEAAVASSPAVLGDRLFVGAADH 299
Query: 749 LLYSLKI 755
LY+L I
Sbjct: 300 NLYALGI 306
Score = 55.6 bits (128), Expect = 5e-06
Identities = 63/343 (18%), Positives = 131/343 (38%), Gaps = 23/343 (6%)
Query: 413 VEFVVQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIE 472
+E +W FD G V P E+ LY G+ G++ ++ + G + +
Sbjct: 67 IEVAAEWQFDVGGAVIGGPVF--DENTLY--AGTADGEVYALDTHVGAERWSFSADGPVS 122
Query: 473 -APILCVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIA 531
P+ V D V VG+ DG + ++ + +W+ + + S +Y
Sbjct: 123 TTPV--VDDGLV-----AVGSSDGHIYGIDADDGTELWRFDTAVRVDSSPAIDDRYVYAG 175
Query: 532 SYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIW 591
S ID + +D ++ A + + T V A + ++ W
Sbjct: 176 SVSNAAYAIDRTNGELHWRFD-ADGSVLASPAVGDETVYVASTDHNVYA-IDPDSGEADW 233
Query: 592 QGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEI 651
Q + G I P L + YV + ++ G W++ G + + SS V
Sbjct: 234 QFTTGGEISVAPTLVGDRLYV--GSRDSSVYAIDTGSGEGRWSF-GLEAAVASSPAV--- 287
Query: 652 NKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLW 711
+++ G D+N+Y++ I + P W++ P + +D + DG +
Sbjct: 288 --LGDRLFVGAADHNLYALGIGDDSPEGLWRSPTPGAAVGNPAVTDDH-VFFGGRDGAVR 344
Query: 712 VIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLK 754
+ ++ G + ++ + G P + D +++G +Y+ +
Sbjct: 345 ALRTDGGDRSWEHDVDGGIQGGPALTDRWLYVGTDAGTVYAFR 387
Score = 37.5 bits (83), Expect = 1.3
Identities = 16/76 (21%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 681 WKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDH 740
W+ V V P +F++ + A + DG+++ + + +G + G ++P++ D
Sbjct: 73 WQFDVGGAVIGGP-VFDENTLYAGTADGEVYALDTHVGAERWSFSADGPVSTTPVVDDGL 131
Query: 741 VFIGCRNDLLYSLKID 756
V +G + +Y + D
Sbjct: 132 VAVGSSDGHIYGIDAD 147
>UniRef50_Q89T13 Cluster: Bll2237 protein; n=2; Bradyrhizobium|Rep:
Bll2237 protein - Bradyrhizobium japonicum
Length = 2154
Score = 68.1 bits (159), Expect = 8e-10
Identities = 86/334 (25%), Positives = 143/334 (42%), Gaps = 26/334 (7%)
Query: 23 VLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELK 82
+L E +T + PS + + IL A + L++L GEPL + + +
Sbjct: 1315 LLAREIEREGITVLEIVPSLLRVIVDRMDEAPILRAFARLRLLISTGEPLP-VDLCRAWF 1373
Query: 83 HKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFV-----QPHE 137
+ K + YG +E S S+ L T VP+G L T+L+V +P
Sbjct: 1374 ARCPKVPLINAYGASECSDDVSLHRLT-KPPATATSNVPVGAPLPNTQLYVLDANLEPQP 1432
Query: 138 KNNTMGKIILASKTRKCILLNRKNGNKE---------ENSIKFIDTGDIGEIR-NGTVFY 187
T G++ + +N NK+ + + + TGD+ R +GT+
Sbjct: 1433 VGVT-GELCIGGAGVGRGYINDPAQNKQRFLPDPFLRQAASRLYRTGDLARRRADGTIEC 1491
Query: 188 RGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP---LLLIVYFSAET---LS 241
GR D +K G++I L IE+ + P VR+ + + LI + A +S
Sbjct: 1492 LGRADHQVKVRGYRIELKEIENALADHPSVRAGIVEPRREASGDVRLIAHIVARPGSRVS 1551
Query: 242 SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE-ILVNIYKKSNILQNVENIKSY 300
+ EL DFLK +L P + +D +P NAHGK + +L ++++ + +
Sbjct: 1552 ASELRDFLKSRLPGHAIPSAFLFMDQVPLNAHGKIDRSMLLAPAQQEASEPDAAVPARRF 1611
Query: 301 LFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLA 333
K L + L E+L + +FF LGG S LA
Sbjct: 1612 TEKVLSDIWIDLLKVENLSVTDNFFDLGGHSLLA 1645
Score = 45.6 bits (103), Expect = 0.005
Identities = 46/203 (22%), Positives = 82/203 (40%), Gaps = 12/203 (5%)
Query: 90 IFTLYGVTEMSCWASVAELDLNKV-TTGDKEVPLGNCLSETELFVQPHEKNNTMGKIILA 148
+ YG+TE + + +L K+ + G P + ET + + G+I+L
Sbjct: 323 VLETYGMTEAASQIAANPFELRKLGSVGRAAGPEIAVMDETGRALA----SGAHGEIVLR 378
Query: 149 SKTRKCILLNRKNGNKEENSIKFIDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSI 207
N + + + TGD+G + +G +F GR+ D I R G KI+ +
Sbjct: 379 GANMSRGYYNDEAATQAAFRDGWFRTGDLGYLDADGYLFIVGRIKDVINRGGQKISPLEV 438
Query: 208 ESTVMQCPRVRSCSCVWLQTPLL------LIVYFSAETLSSQELLDFLKCKLDEKYWPDK 261
E ++ P V + P L ++V + +S +L F + +L P
Sbjct: 439 EEVLLSHPAVLEAGVFAVPHPKLGENVAAVVVLRANSEATSDQLRKFARKRLAAYKVPSL 498
Query: 262 VIRVDTLPTNAHGKTSKEILVNI 284
+ V LP A GK + L ++
Sbjct: 499 IRSVAALPKGASGKVKRNALADL 521
>UniRef50_Q63CQ5 Cluster: Multifunctional nonribosomal peptide
synthetase; n=1; Bacillus cereus E33L|Rep:
Multifunctional nonribosomal peptide synthetase -
Bacillus cereus (strain ZK / E33L)
Length = 2295
Score = 68.1 bits (159), Expect = 8e-10
Identities = 72/290 (24%), Positives = 128/290 (44%), Gaps = 23/290 (7%)
Query: 67 LGGEPLNGIKILKELKHKNNKTR-IFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNC 125
LG EPL I K NK + I LYG TE + AS D ++V +G
Sbjct: 463 LGAEPLPADLITKFSDLCPNKIKDISNLYGPTESTVVASAYFYDEQSSL---EDVSVGKP 519
Query: 126 LSETELFVQPHEKN---NTMGKIILASKTRKCILLNRKNGNKEENSI-------KFIDTG 175
+ E+++ K + G++ + + LN+ E+ + + TG
Sbjct: 520 IGNGEIYIVKDNKLCGISMEGELCVGGEGVTRGYLNQPVLTDEKYVVIPEISNGRIYKTG 579
Query: 176 DIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT---PLLL 231
D+G R +GT+ GR D+ +K G++I L IES + Q + ++ Q+ PL +
Sbjct: 580 DVGYWREDGTLKLLGRRDEQVKINGYRIELSEIESGLRQIEGINDAVVIYDQSEKIPLFV 639
Query: 232 IVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGK-TSKEILVNIYKKSNI 290
Y + S+ ++ + L+ L P+ +++V+ P GK K+++++ +
Sbjct: 640 AFYRGTKFESTNKIKELLRKNLPSYMIPNDIVKVEDFPQTVGGKLDKKKLILDFIDNVSK 699
Query: 291 LQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKL 340
++ L + L K++ ED +FF LGG S A+ I +KL
Sbjct: 700 TDKSGSVNKVLLVFSEVLGKKEVVMED----NFFELGGDSIKAIQIISKL 745
>UniRef50_Q8VQF8 Cluster: Peptide synthetase XpsB; n=1; Xenorhabdus
bovienii|Rep: Peptide synthetase XpsB - Xenorhabdus
bovienii
Length = 3316
Score = 68.1 bits (159), Expect = 8e-10
Identities = 82/369 (22%), Positives = 150/369 (40%), Gaps = 34/369 (9%)
Query: 1 MVEILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTT-------PSKFFQHSNENIKN 53
+ EI GA++++ PD +V + +TF Q P+ F+ + I
Sbjct: 710 VAEIFPTFAIGATVVLRPDHIKV----PDTEFITFLQNQGITVVDLPTAFWHLWAQEISA 765
Query: 54 KILCARSTLKVLALGGEPLNGIKILKELKHKNN-KTRIFTLYGVTEMSCWASVAELDLNK 112
L+ +A GGE ++ L K R YG TE + A+ +D
Sbjct: 766 GYSWPPEQLRSVAAGGEKAEHRHLVTWLSSPGTQKCRWLNTYGPTETTVNATSIVIDKEN 825
Query: 113 VTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE-- 166
+ T + ++P+G ++ T +++ G+I ++ LNR E
Sbjct: 826 LCTYE-DIPIGRPIANTRIYILDQRGQPVPIGVNGEIHISGSGVARGYLNRSELTAERFI 884
Query: 167 -------NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR 218
+ TGD+G + +GT+ Y GR D +K G +I L IE+ + C V+
Sbjct: 885 QDPFSDIPGARMYKTGDLGRWLPDGTISYSGRNDFQVKIRGFRIELGEIEAQLATCAGVK 944
Query: 219 SCSCVWLQT---PLLLIVYF---SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNA 272
+ + L+ Y S L++ L + L L + P + ++ P N
Sbjct: 945 DAVVIVREDDNGDKRLVAYLIPQSGAILNAASLREQLSVNLADYMLPSAFVTLEAFPLNQ 1004
Query: 273 HGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSF 331
+GK + L + +++ + + + ++L A+ L E + + SFF LGG S
Sbjct: 1005 NGKIDRPALPAPDRSASVSREYAEPQGEIEQQLAAIWQNLLGLERIGRYDSFFELGGHSL 1064
Query: 332 LAVTICNKL 340
L V + ++L
Sbjct: 1065 LTVQVASRL 1073
Score = 58.8 bits (136), Expect = 5e-07
Identities = 49/185 (26%), Positives = 83/185 (44%), Gaps = 8/185 (4%)
Query: 164 KEENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
+E+ + TGD+G R +GT+ Y GR D +K G +I L IES + C V
Sbjct: 1963 REQPHARMYRTGDLGCWRPDGTIVYLGRNDFQVKIRGFRIELGEIESQLAACTGVSDAVV 2022
Query: 223 VWLQT---PLLLIVYF---SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
V + L+ Y S TL + L + + L E P + +D P N +GK
Sbjct: 2023 VAREEGSGDKRLVAYLVPKSDVTLDAASLREQVSTHLAEYMLPSAFVILDAFPLNPNGKL 2082
Query: 277 SKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVT 335
++ L + + + + + + ++L + L E + + +FF LGG S L V+
Sbjct: 2083 DRKALPAPDHAATVSREYQAPQGEMEQQLAVIWQTLLGLEQVGRQDNFFELGGHSLLVVS 2142
Query: 336 ICNKL 340
+ +L
Sbjct: 2143 LIEQL 2147
Score = 50.4 bits (115), Expect = 2e-04
Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 8/188 (4%)
Query: 165 EENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
E+ + + TGD+G + +GT+ Y GR D +K G +I L IE+ + C V+ V
Sbjct: 3070 EQPNARMYRTGDLGCWQPDGTIVYLGRNDFQVKLRGFRIELGEIETQLAACLGVKDAVVV 3129
Query: 224 WLQTPL---LLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ L+ Y + +L + L + L L E P + +D P GK
Sbjct: 3130 AREEDAGDKRLVAYVIPQPDASLDAASLREQLSTHLTEYMLPSAFVILDAFPLTPSGKLD 3189
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTI 336
++ L + ++ E + + +L A+ L E + + +FF LGG S + +
Sbjct: 3190 RKALPAPGRSASTSHEYEAPQGEIEPQLAAIWQTLLGLEQVGRHDNFFELGGNSLSIMRL 3249
Query: 337 CNKLSLTF 344
L F
Sbjct: 3250 STHLREEF 3257
>UniRef50_Q84FL2 Cluster: AdmK; n=2; Gammaproteobacteria|Rep: AdmK -
Enterobacter agglomerans (Erwinia herbicola) (Pantoea
agglomerans)
Length = 575
Score = 68.1 bits (159), Expect = 8e-10
Identities = 68/296 (22%), Positives = 127/296 (42%), Gaps = 14/296 (4%)
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
A + L+ L +GG+ ++ + L+ N T+++ YG TE + + +VA LDL+K+ +
Sbjct: 257 ALARLRHLIVGGDKVDFHAAVSFLERSPN-TQLYNGYGPTENTVFTTVALLDLHKLKR-E 314
Query: 118 KEVPLGNCLSETE-LFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSI------- 169
K VP G + + L H I T + + L + E +
Sbjct: 315 KRVPTGKLVGGGDYLLFDEHTGEYRKSGIGRLHVTGRGLSLGYHDNPVETGKVFTIIDGT 374
Query: 170 KFIDTGDIGEIRNGTVFY-RGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP 228
++ DTGDI E FY GR D +K GH++ L IE T+ + C +
Sbjct: 375 RYYDTGDIVECTLDREFYFLGRQDRQVKLNGHRVELDDIEKTLENDRSIVKALCFIWNSH 434
Query: 229 LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L+ ++ +T + + L+ +L +PD +I P +GK + L+N
Sbjct: 435 LVSLIEIQDKTANLDTIATRLRSQLSSFSFPDFLIENTQWPLTKNGKIDTKSLINQTINH 494
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTF 344
++ ++ + + +++K + +L F LG S +T ++L+ F
Sbjct: 495 LEMRQTDSAGRSVKSVAEQVLDKPV---ELLDAGLFDLGFDSISMLTFSHELNKQF 547
>UniRef50_Q6E7J5 Cluster: JamO; n=1; Lyngbya majuscula|Rep: JamO -
Lyngbya majuscula
Length = 1158
Score = 67.7 bits (158), Expect = 1e-09
Identities = 83/369 (22%), Positives = 159/369 (43%), Gaps = 39/369 (10%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTL 62
EI + + G +++A + ++ + + +T T PS + S N ++
Sbjct: 743 EIFVTLSQGGQVILAQNALDL---PNIKSEITLINTVPSAITELSRIN------AIPDSV 793
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
KV+ L GEP + ++L+ L + N ++ LYG +E + + + L K TT + +
Sbjct: 794 KVINLAGEPFSN-QLLQRLYQQENIQSVYNLYGPSEYTTYTTFTLL--KKGTT--TQPTI 848
Query: 123 GNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE---------NSI 169
G+ ++ T++++ +G++ + NR E+ S
Sbjct: 849 GHPIANTQVYILDSHLQPVPIGVVGELYIGGDGLARGYHNRPELTAEKFIPNPFDNSTST 908
Query: 170 KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP 228
+ TGD+ + +G + + GR+D +K G +I + IE+ V Q P V+ + + P
Sbjct: 909 RLYKTGDLARYLPDGNIAFIGRIDHQVKIRGFRIEMGEIEAFVSQYPDVKENAVIAQSDP 968
Query: 229 L---LLIVYFSAETLSSQE------LLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
L+VY + S+Q+ + FLK KL E P + +D P +GK +
Sbjct: 969 AGGKRLVVYIVPKQESTQDTSLIPHIRKFLKQKLPEYMIPAAFVLLDAFPLTPNGKIDRR 1028
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKD-LNYEDLQ-SKSFFSLGGTSFLAVTIC 337
L + L V + ++L A + ++ L E + +FF LGG S L + +
Sbjct: 1029 ALPVPDTVPSGLSTVYVMPQTETEQLIAKIWQEVLQIEKVGIYDNFFELGGHSLLIIKVH 1088
Query: 338 NKLSLTFPE 346
KL + +
Sbjct: 1089 KKLQEVYAQ 1097
>UniRef50_A5I518 Cluster: Putative AMP-binding enzyme; n=4;
Clostridium botulinum|Rep: Putative AMP-binding enzyme -
Clostridium botulinum A str. ATCC 3502
Length = 609
Score = 67.7 bits (158), Expect = 1e-09
Identities = 76/295 (25%), Positives = 130/295 (44%), Gaps = 27/295 (9%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAEL--DLNKVTTGD 117
+ L+VL GGE K K+K +F YG+TE +V ++ D ++ GD
Sbjct: 292 NVLRVLYFGGE--------KFCKNKVTNYELFNSYGLTETGILNTVYKIKGDEREIPLGD 343
Query: 118 KEVPLGNCLSETELFVQPHEKNNTM---GKIILASKTRKCILLNRKNGN-KEENSIKFID 173
+ G + + + + P K + G I L N+K KE +++
Sbjct: 344 PIINSGILILDDQDKIIPKGKLGEIAIFGSGIAIEYDNNTELTNKKFIKLKEMGNLRCCK 403
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR-SCSCVWLQTPLLL 231
TGD+G I N ++++GR D +K G++I L I + + + S V + L L
Sbjct: 404 TGDLGYINENDNLYFKGRKDKQVKISGYRIELDEIRFYLQKYACIELSIPMVIKKGKLSL 463
Query: 232 IV--YFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS----KEILVN-- 283
+V Y + E L + + FL L P I + +P +GK ++I N
Sbjct: 464 LVNFYVAKEVLDEELINKFLSKYLPFYMVPLCHINIKDVPYTTNGKVDYRGLQKIFENKK 523
Query: 284 --IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTI 336
+Y KSN+L + +K +L ++ D + E ++ SFF +GG S A+ +
Sbjct: 524 EKVYLKSNLLYSKLELKEFLIDTYANILKMDKD-EIMEDGSFFEMGGDSLKAMKL 577
>UniRef50_A0UVH3 Cluster: Amino acid adenylation domain; n=1;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 2006
Score = 67.7 bits (158), Expect = 1e-09
Identities = 85/368 (23%), Positives = 160/368 (43%), Gaps = 39/368 (10%)
Query: 29 NDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKT 88
++ VT Q PS EN K C R + GGE L+ +++ K +
Sbjct: 733 SEKKVTTIQFVPSMLRAFLEENEIKKANCLRRVIS----GGEALS-VELHDRFFEKLD-V 786
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKE--VPLGNCLSETELFVQPHEKN------- 139
+ YG TE + ++ K G K +P+G+ L+ T+L++ N
Sbjct: 787 ELHNQYGPTE-----AAIDVTYWKCYKGCKRHTIPIGHPLANTKLYILDKYFNPVPIGVP 841
Query: 140 ---NTMGKIILASKTRKCILLNRK---NGNKEENSIKFIDTGDIGEIRN-GTVFYRGRVD 192
+ G + + + L N K N +++ + TGD+ N G++ + GR+D
Sbjct: 842 GELHICGDGLASGYLNRPELTNEKFISNPFSDKHGGRLYKTGDLVRYANDGSIEFIGRID 901
Query: 193 DTIKRFGHKINLHSIESTVMQCPRVR-SCSCVW-----LQTPLLLIVYFSAETLSSQELL 246
+K G +I L IE+ ++Q P V S VW ++ + IV S + ++ EL
Sbjct: 902 HQVKIRGLRIELGEIEAMLLQHPDVHASAVIVWEGSEDVKRLVAYIVMESGKEFNTTELR 961
Query: 247 DFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI-YKKSNILQNVENIKSYLFKEL 305
+LK KL + P ++ +D LP GK K L + + + + Q ++++ + L
Sbjct: 962 SYLKAKLPDYMVPAVLMNIDALPLTTSGKLDKRGLPAVDFSRDMMEQPFAAPRNHVEETL 1021
Query: 306 KALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGD 364
+ L E++ FF LGG S L++ + + + G +I P + +++I +
Sbjct: 1022 AGIWADILKLEEVGIHDRFFELGGDSILSIQVVARAR----QSGIYITPKQIFEHQTIEE 1077
Query: 365 VLKTITQD 372
+ + + +
Sbjct: 1078 LAQVVNTE 1085
>UniRef50_Q6D9Y3 Cluster: Enterobactin synthetase component F; n=4;
Gammaproteobacteria|Rep: Enterobactin synthetase
component F - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 1047
Score = 67.3 bits (157), Expect = 1e-09
Identities = 75/357 (21%), Positives = 143/357 (40%), Gaps = 20/357 (5%)
Query: 3 EILLACTNGASLLIAPD-LTEVL--FHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCAR 59
E+ T+GA+L++ D + E + F E D P+ F+ +K L
Sbjct: 659 EVFATLTSGATLVLRTDEMLESIPTFVEQVDAQAITLLDLPTAFWNEWVVGLKTGTLTMP 718
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S L+ + +GGE + ++++ +H + R+ YG TE + A+ +L +
Sbjct: 719 SALRAIIIGGEAVYPEQLVQWQRHAPDTLRLINTYGPTETTVVATSCDLQTQPADVA--Q 776
Query: 120 VPLGNCLSETE-LFVQPHEKNNTMGKIILASKTRKCILLNRKNG-----NKEENSIKFID 173
+P+G L+ L + ++ G+++L T + ++ + +
Sbjct: 777 LPIGLPLAGVNALVLAAGDRPAAEGELVLLGPTLAAGYIGTEHTAFTLLAVGDRHLPAYR 836
Query: 174 TGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP----- 228
TGD + G + Y GR+D+ K G++I +E+ ++ P V + P
Sbjct: 837 TGDRVRLEKGHLLYLGRMDNEFKISGYRIQPGEVEAHLLAQPEVDEACVQGIVYPNGVRR 896
Query: 229 LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L+ V + ++ L L L P LP K ++ L+ Y
Sbjct: 897 LVAFVATKEGEIDARALKQRLSSVLPPAMIPTDYRAFHQLPKTGSNKVDRKRLLAEYHDD 956
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKLSLTF 344
+ + S + A+ + L +QS+ +FF LGG S + I N+L+ F
Sbjct: 957 ---APTQALASETENRVSAIWQQILGVSGIQSRDNFFELGGQSLQTIQIVNRLAAEF 1010
>UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3;
cellular organisms|Rep: Non-ribosomal peptide synthetase
- Erwinia carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 7048
Score = 67.3 bits (157), Expect = 1e-09
Identities = 72/302 (23%), Positives = 127/302 (42%), Gaps = 22/302 (7%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
++LK L + GE +I ++ T ++ YG TE + WASV + + +
Sbjct: 5078 ASLKALIVAGERCPP-EIQTAIEQLGLSTALYNEYGPTEAAVWASVYHVTSTETSRNRLT 5136
Query: 120 VPLGNCLSETELFV-QPHEKN---NTMGKIILASKTRKCILLNRKNGNKE---------E 166
VP+G+ ++ +++++ P + N G+I + LNR + E
Sbjct: 5137 VPIGHPIANSQIYILDPQGRPTLLNVAGEIYIGGAGVARGYLNRPDLTAERFIPDPFSSS 5196
Query: 167 NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW- 224
+ TGD+ + +G + Y GR D +K G +I L IES +MQ P V+
Sbjct: 5197 PEARMYKTGDLARWLPDGNIDYLGRNDFQVKVRGFRIELGEIESRLMQLPGVQEAVVAAR 5256
Query: 225 --LQTPLLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
+ L+ Y ++ L+ EL L L E P + +DT P +GK ++
Sbjct: 5257 EDIPGDTRLVAYLRSQPDAELNPTELRQQLAEHLAEYMVPSAFVTLDTFPLTPNGKIDRK 5316
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICN 338
L + + + L L + L + + + FF LGG S +AV++
Sbjct: 5317 ALPAPDHSAVATRGYVTPQGELETALAQIWQDLLGLDRVGRHDQFFELGGHSLMAVSLIE 5376
Query: 339 KL 340
+L
Sbjct: 5377 RL 5378
Score = 64.5 bits (150), Expect = 1e-08
Identities = 72/303 (23%), Positives = 128/303 (42%), Gaps = 25/303 (8%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKN--NKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
+L+ + GGE L + +L N +TR+ +YG+TE++ A+ EL +T G
Sbjct: 764 SLRCIIFGGEALE-LHMLAPWIADNPLERTRLINMYGITEITVHATFRELSAADITAGRG 822
Query: 119 EVPLGNCLSETELF-VQPHEKN---NTMGKIILASKTRKCILLNRKNGNKE--------- 165
+ +G L + + + PH + G++ + LNR + E
Sbjct: 823 SL-IGRPLPDLRAYLLDPHGQPVPVGVAGELYIGGAGVARGYLNRPDLTAERFIVDPFSD 881
Query: 166 ENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW 224
+ + TGD+ + +GT+ Y GR D +K G +I L IES ++QCP V+ +
Sbjct: 882 SPATRLYKTGDLARWLPDGTLDYLGRNDFQVKVRGFRIELGEIESRLVQCPGVQEAVVLA 941
Query: 225 LQT---PLLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
+ L+ Y + L +L L L + P + ++ P +GK +
Sbjct: 942 REDVPGDTRLVAYIQPQPKAVLEPADLRQQLSTHLADYMIPAAFVTLEAFPLTPNGKLDR 1001
Query: 279 EILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTIC 337
+ L + + + + E + L + L E + + FF LGG S L V++
Sbjct: 1002 KALPAPERSAVVTRGYEEPVGDIETALAEIWQDLLGLERVGRYDHFFELGGHSLLIVSLI 1061
Query: 338 NKL 340
KL
Sbjct: 1062 EKL 1064
Score = 59.7 bits (138), Expect = 3e-07
Identities = 58/217 (26%), Positives = 97/217 (44%), Gaps = 12/217 (5%)
Query: 166 ENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW 224
++ + TGD+ + +G++ Y GR D +K G +I L IE+ +MQCP V+ V
Sbjct: 6279 QHGARLYKTGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVA 6338
Query: 225 LQ-TP--LLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
+ +P L+ Y + L EL L L + P + +DT P +GK +
Sbjct: 6339 REDSPGDTRLVAYLCPQPSIELMPAELRQQLSTHLADYMIPSAFVMLDTFPLTPNGKLDR 6398
Query: 279 EILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTIC 337
+ L + + + E + + +L + L E + + FF LGG S LAV +
Sbjct: 6399 KALPAPDQTAVVSHGYEAPQGKVEMKLAHIWQMLLGLERVGRHDHFFELGGHSLLAVQLL 6458
Query: 338 NKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQDTN 374
N + EV L L SH ++ D+ + DT+
Sbjct: 6459 NHMREQSMEVS---LATLFSH-PTLCDLAFVVGSDTS 6491
Score = 51.2 bits (117), Expect = 1e-04
Identities = 47/175 (26%), Positives = 81/175 (46%), Gaps = 8/175 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ-TP--L 229
TGD+ + +G++ Y GR D +K G +I L IE+ +MQCP V+ V + +P
Sbjct: 3048 TGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVAREDSPGDT 3107
Query: 230 LLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L+ Y + T +L L L E P + +D P +GK ++ L +
Sbjct: 3108 RLVAYLCPQPGITPDPADLRQQLGQHLAEYMVPGAFVTLDAFPLTPNGKLDRKALPAPDQ 3167
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ ++ E + + L A+ L + + FF+LGG S +AV++ +L
Sbjct: 3168 SAVATRDYEAPQGEVETALAAVWQDLLGLTRVGRHDHFFALGGHSLMAVSLIERL 3222
Score = 50.0 bits (114), Expect = 2e-04
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 8/184 (4%)
Query: 165 EENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
++ + TGD+G + +G + Y GR D +K G +I L IE+ ++QC V+ +
Sbjct: 4113 DDPDARLYKTGDLGRWLNDGNIDYLGRNDFQVKVRGFRIELGEIEARLIQCSGVKEAVAI 4172
Query: 224 WLQ-TP--LLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ TP L+ Y A+ L EL L L E P + ++ P +GK
Sbjct: 4173 AREDTPGETRLVAYLIAQPGVELVPAELRQQLAHHLAEYMVPSAFVTMEAFPLTPNGKLD 4232
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTI 336
++ L + + + + E L ++ L + + FF LGG S +AV +
Sbjct: 4233 RKALPVPDQTAIVTRTYEAPVGEKETILASIWQHLLGLTHVGRRDQFFELGGHSLMAVNL 4292
Query: 337 CNKL 340
+L
Sbjct: 4293 IERL 4296
Score = 38.3 bits (85), Expect = 0.76
Identities = 61/276 (22%), Positives = 105/276 (38%), Gaps = 31/276 (11%)
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGK 144
++ YG TE + A++ TGD +P+G + T +++ + G+
Sbjct: 1875 QVINAYGPTESTVCATIYHYH----RTGDDFLPIGKPIDNTHVYILDAKGQLAPLGVAGE 1930
Query: 145 IILASKTRKCILLNRKNGNKE---------ENSIKFIDTGDIGE-IRNGTVFYRGRVDDT 194
+ L LNR E + + TGD+G + +G + Y GR D
Sbjct: 1931 MYLGGVGIARGYLNRPELTAERFIPDPYSDQPGARMYKTGDLGRWLADGNIEYLGRNDFQ 1990
Query: 195 IKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ---TPLLLIVYFSAET---LSSQELLDF 248
IK G +I IE+ +M C V+ + + L+ Y + L
Sbjct: 1991 IKLRGFRIEPGEIEARLMGCSGVQDAVVIVREDNPNDKRLVAYIRPHVGAEIEPAALRLQ 2050
Query: 249 LKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVE----NIKSYLFKE 304
L L E P + ++ P +GK ++ L S ++ E +++ L
Sbjct: 2051 LSQHLAEYMLPAAFVTLEQFPLTPNGKLDRKALPAPDLLSVATRSYEAPQGDVEIALADS 2110
Query: 305 LKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKL 340
K L+ D + FF LGG S +AV + +L
Sbjct: 2111 WKTLLQLD---RVGRHDHFFELGGHSLMAVNLIERL 2143
>UniRef50_Q48D76 Cluster: Non-ribosomal peptide synthetase; n=1;
Pseudomonas syringae pv. phaseolicola 1448A|Rep:
Non-ribosomal peptide synthetase - Pseudomonas syringae
pv. phaseolicola (strain 1448A / Race 6)
Length = 510
Score = 67.3 bits (157), Expect = 1e-09
Identities = 64/238 (26%), Positives = 108/238 (45%), Gaps = 16/238 (6%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKN--NKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
T++ + GEPL +++K++K + TRI LYG E S + + + + D
Sbjct: 278 TVRTIMFCGEPLEQ-QLVKKVKDSFPFSHTRILNLYGPVEASVQVTYCWAE-EYLGSEDV 335
Query: 119 EVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNG-----NKEENSIKFID 173
+PLG L + V+ E ++T ++ + L+ K N E +F
Sbjct: 336 IIPLGKPLKH--VVVRLAEVDDTSHELQITGDHLALRYLDEKKTRESFINDEAEGTRFYR 393
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT---PL 229
TGD+G + G + Y GRVDD +K G++I L IE T++ + C CV ++
Sbjct: 394 TGDLGRLNARGDLEYHGRVDDQVKINGYRIELGEIEKTIIDHFKATDC-CVLIEKSEGEP 452
Query: 230 LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK 287
L+ + + S +L + L P VI ++++P N +GK K L Y K
Sbjct: 453 SLVAFVVSPNDSVADLRRAVADHLPTYMIPRTVIFIESIPLNTNGKRDKPSLRAEYLK 510
>UniRef50_Q094I7 Cluster: Aminotransferase, class III family; n=9;
cellular organisms|Rep: Aminotransferase, class III
family - Stigmatella aurantiaca DW4/3-1
Length = 3433
Score = 67.3 bits (157), Expect = 1e-09
Identities = 86/353 (24%), Positives = 148/353 (41%), Gaps = 34/353 (9%)
Query: 89 RIFTLYGVTEMSCWASVAELDLNK--VTTGDKEVPLGNCLSETELFV-----QPHEKNNT 141
R++ LYG TE + W+S + + D PLG L+ T+L+V QP T
Sbjct: 2809 RLWNLYGPTETTIWSSAHRVQASPHGAERADASEPLGQPLANTQLYVLSPALQPVPLGVT 2868
Query: 142 MGKIILASKTRKCILLNRKNGNKE---------ENSIKFIDTGDIGEIR-NGTVFYRGRV 191
G++ + L + + E + + TGD+ R +GT+ + GR
Sbjct: 2869 -GELFIGGMGLAQSYLGQPSLTAEKFVPDPFSGQPGARLYRTGDLVRYRPDGTLEFFGRT 2927
Query: 192 DDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP-----LLLIVYFSAE-TLSSQEL 245
D +K G +I L +IE+ + Q P V + + + + L V F E + + L
Sbjct: 2928 DFQVKIRGFRIELGAIEAALAQHPAVANVALIAREVKPGDSRLFAYVVFQREQAVPPEAL 2987
Query: 246 LDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKEL 305
+FL+ KL P +I V+ LP +GK ++ L + + + ++ L EL
Sbjct: 2988 AEFLQSKLPGYMVPGAIIPVEELPLTPNGKVDRKALAALDVGRWLSKVHVAPRTPLESEL 3047
Query: 306 KALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGD 364
L + L + + +FF LGG S L V + ++ + +G+ + LL +I
Sbjct: 3048 VQLWEEVLGTRPVGVTDNFFQLGGNSLLGVRLMTRIRRS---LGQEVPLSLLLEEPTIDH 3104
Query: 365 VLKTITQD----TNCLENKFKKSIKRNRSTSSHGENSISYKKGAGGIRNSNTV 413
+ + I Q + K + + R H N + + GGI SN V
Sbjct: 3105 LAQFIAQQNLVKAPVAPGQDKTPLVKVRPEGGH--NPLFFAAQLGGIFPSNVV 3155
>UniRef50_Q8YWC0 Cluster: All1695 protein; n=1; Nostoc sp. PCC
7120|Rep: All1695 protein - Anabaena sp. (strain PCC
7120)
Length = 1449
Score = 66.9 bits (156), Expect = 2e-09
Identities = 77/310 (24%), Positives = 140/310 (45%), Gaps = 36/310 (11%)
Query: 3 EILLACTNGASLLIAP----DLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCA 58
EI A NG L++ P L E+ + T W T + F N ++ +I
Sbjct: 232 EIWAALLNGGKLVLMPINIPSLQEIGMAIKQYHVTTLWLT--AGLF---NLMVEEQIEHL 286
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
+S ++LA GG+ L+ + K ++ N ++ YG TE + + ++ +N +
Sbjct: 287 KSLRQLLA-GGDVLSVYHVSKVIEELPN-CQLINGYGPTENTTFTCCHKITVNDLIKDS- 343
Query: 119 EVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE-------- 166
+P+G ++ T++++ G++ + LN+ + E+
Sbjct: 344 -IPIGRPIANTQVYILDDVLQLVPIGIAGELYIGGDGLARGYLNKPDLTAEKFIPHPFSD 402
Query: 167 --NSIKFIDTGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
NS + TGD + + +GT+ + GR+D +K G ++ L IE+ + Q P VRS +
Sbjct: 403 KPNS-RLYKTGDRVRWLPDGTIEFLGRIDFQVKIRGFRVELGEIEAILAQHPSVRSAVVL 461
Query: 224 ---WLQTPLLLIVYFSAE----TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
+ L+ YF+ E T++ EL FL+ KL P I ++ LP NA+GK
Sbjct: 462 AQEYQPADKRLVAYFTREENCNTVAPSELRHFLQQKLPNYMIPSAFISLEKLPLNANGKV 521
Query: 277 SKEILVNIYK 286
++ L N+ K
Sbjct: 522 DRKALPNVDK 531
>UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Rep:
Iturin A synthetase A - Bacillus subtilis
Length = 3982
Score = 66.9 bits (156), Expect = 2e-09
Identities = 71/310 (22%), Positives = 139/310 (44%), Gaps = 25/310 (8%)
Query: 51 IKNKILCARSTLKVLALGGEPLNGIKILKELKHK-NNKTRIFTLYGVTEMSCWASVAELD 109
IK + + ++ + +GGE L+ ++ K + + + IF YG TE + D
Sbjct: 3194 IKEMNIAGDTAIRKMIVGGENLS-TRLAKSVSEQFKGRLDIFNEYGPTEAVVGCMIYHFD 3252
Query: 110 LNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE 165
V + VP+G + T+++V +N +G+I ++ NR + +E
Sbjct: 3253 A--VRDKREFVPIGTPAANTDIYVADASRNLVPIGVIGEIYISGPGVARGYWNRPDLTEE 3310
Query: 166 ---EN----SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV 217
EN K +GD+ + +++G + Y GRVD+ +K GH+I L IE+ + V
Sbjct: 3311 KFVENPYVPGAKMYKSGDLAKRLKDGNLVYIGRVDEQVKIRGHRIELGEIEAAMHNAEAV 3370
Query: 218 RSCSCVWLQ----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAH 273
+ + + L Y S + +++ +L + L L + P +R++ +P ++
Sbjct: 3371 QKAAVTVKEEEDGLKQLCAYYVSDKPIAAAQLREQLSSGLPDYMVPSYFVRLEHMPLTSN 3430
Query: 274 GKTSKEILVNIYKKSNILQNVENIK--SYLFKELKALVNKDLNYEDLQSK-SFFSLGGTS 330
GK +++ L +S++ Q E + + +L L + L K +FF LGG S
Sbjct: 3431 GKINRKALP--APESSLQQTAEYVPPGNETESKLTDLWKEVLGISHAGIKHNFFDLGGNS 3488
Query: 331 FLAVTICNKL 340
A + ++
Sbjct: 3489 IRAAALAARI 3498
>UniRef50_Q2VQ17 Cluster: Nonribosomal peptide synthetase A; n=1;
Brevibacillus texasporus|Rep: Nonribosomal peptide
synthetase A - Brevibacillus texasporus
Length = 641
Score = 66.9 bits (156), Expect = 2e-09
Identities = 72/334 (21%), Positives = 147/334 (44%), Gaps = 24/334 (7%)
Query: 30 DNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTR 89
+ VT TP+ F+Q S++ +++ + +++ + GGE L + LK K K T
Sbjct: 261 EQKVTILNQTPTAFYQLSSQEMQHSD--SNLSIRKIIFGGEALTPSQ-LKAWKQKYPNTA 317
Query: 90 IFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKI 145
+ +YG+TE + + E L+ + + + G + +V ++N G++
Sbjct: 318 LINMYGITETTVHVTYKEFQLHDMDSTVSNI--GKPIPTLRTYVLDSKRNLAPIGVKGEL 375
Query: 146 ILASKTRKCILLNRKNGNKE---ENSI----KFIDTGDIGE-IRNGTVFYRGRVDDTIKR 197
++ K LN+ +E +N + TGD+ + G + Y GR+D +K
Sbjct: 376 YVSGKGVARGYLNKPELTEERFMDNPFVAGERMYRTGDLARWLPEGELEYLGRIDHQVKI 435
Query: 198 FGHKINLHSIESTVMQCPRVRSCSCVWLQ----TPLLLIVYFSAETLSSQELLDFLKCKL 253
G++I L IE+ +++ ++ + P L S E L++ +L + L L
Sbjct: 436 RGYRIELGEIEAELLKQKGIKEAVVLVTNDKDAQPQLHAYLTSKEDLAAADLRNQLTTTL 495
Query: 254 DEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK--KSNILQNVENIKSYLFKELKALVNK 311
P I V +P +GK KE L I + + + ++ K+L + +
Sbjct: 496 PSYMIPAHFIFVSQMPVTPNGKIDKESLRKIEPSLQESPTEAYVAPQTPTEKQLVHIWEE 555
Query: 312 DLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
++ + + ++F+LGG S A+ + + ++ F
Sbjct: 556 NIGMQPISIDDNYFALGGDSIKAIKLLHAINKEF 589
>UniRef50_Q2ANW8 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Bacillus weihenstephanensis KBAB4|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Bacillus weihenstephanensis KBAB4
Length = 4080
Score = 66.9 bits (156), Expect = 2e-09
Identities = 66/307 (21%), Positives = 139/307 (45%), Gaps = 22/307 (7%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD-K 118
S L+++ +GGE + K+ + + YG E + +++ E+ + + D K
Sbjct: 2236 SNLRLVIVGGEQMPAEKVGMWEQLPLEDIILLNAYGPAETAMTSTLYEVSGKRTKSADLK 2295
Query: 119 EVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE-------- 166
+P+G L+ +++ + G+I + +N K++
Sbjct: 2296 VIPVGKPLANRRIYILDENMHPLPIGVKGEIFIGGIPLARGYINNSKLTKDKFIRDPYYH 2355
Query: 167 NSIKFI-DTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV- 223
N K + TGD+G++ +G + GR DD K GH+I++ IE + +C +++ V
Sbjct: 2356 NYGKMLYKTGDMGKLLCDGNIEVLGRKDDQTKIRGHRIDIGEIEVVLNKCDNIKNSIVVV 2415
Query: 224 --WLQTPLLLIVYF---SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
+ L+ ++ S T + + FL+ KL E P I++ +LP + +GK +
Sbjct: 2416 KNGVANDKYLVAFYDSPSNGTNNQCSIRGFLRKKLPEYMIPSYFIQLGSLPLSPNGKIDR 2475
Query: 279 EILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTIC 337
+ L N+ K + + + + ++L ++ K L + + + FF +GG S A+T+
Sbjct: 2476 KSLENMEIKVQFDEEYQKPYNTIQQKLVSIWRKILGTDGVGINHHFFEIGGQSLKAITLV 2535
Query: 338 NKLSLTF 344
+++ F
Sbjct: 2536 SEIHREF 2542
Score = 48.8 bits (111), Expect = 5e-04
Identities = 59/253 (23%), Positives = 111/253 (43%), Gaps = 25/253 (9%)
Query: 108 LDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKT--RKCILL---- 157
+D V + V LG +S ++ +KN G++ +A R + L
Sbjct: 760 VDALSVECSENTVSLGRPISNVRCYILDKDKNISPIGVPGELYIAGDGVGRGYLNLPEFT 819
Query: 158 NRKNGNKEEN-SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCP 215
N K N N + + TGD+G + NG + + GR D +K G++I L I + +++
Sbjct: 820 NEKFMNDPFNPNDRMYKTGDLGRWLPNGEIEFLGREDHQVKIRGYRIELSEIHNLILKRN 879
Query: 216 RVRSCSCV-WL--QTPLLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTN 271
+ + + W ++ Y + ++ +EL FL +L + P I++++LP
Sbjct: 880 YIEDVAVIDWEINNGKKVICAYIVSHVQVNMEELKGFLAKELPDYMLPSYYIQLESLPLT 939
Query: 272 AHGKTSKEIL----VNIYKKSNILQN-VENIKSYLFKELKALVNKDLNYEDLQSKSFFSL 326
+ GK + L ++ YK +N V+ ++ + L ++ D +FF L
Sbjct: 940 SIGKLDRRNLPAPQIHTYKGYVAPKNKVQEELVEVWSAVLGLHQGEIGIHD----NFFEL 995
Query: 327 GGTSFLAVTICNK 339
GG S L++ I K
Sbjct: 996 GGDSILSIQIVGK 1008
>UniRef50_Q0S5F4 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 8344
Score = 66.9 bits (156), Expect = 2e-09
Identities = 90/358 (25%), Positives = 148/358 (41%), Gaps = 38/358 (10%)
Query: 7 ACTNGASLLIAPDLTEVLFHEDND----NSVTFWQTTPSKFFQHSNENIKNKILCARSTL 62
A T G L++ HE D VT TPS F Q E+I + S+L
Sbjct: 4727 ALTTGGRLVLVDHYLARSPHEFADLLVREGVTVLNQTPSAFGQLV-EHIDS------SSL 4779
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
++L GGE L+ + L H N R ++G+TE + V DL +GD+ +
Sbjct: 4780 RLLIFGGEALDHTLVASWLGHHPN-VRAVNMFGITETT--VHVTRHDLK---SGDERRSV 4833
Query: 123 GNCLSETELFVQPHEKNN----TMGKIILASKT-------RKCILLNRKNGNKEENSIKF 171
G L +V ++ T+G++ ++ R + R + +
Sbjct: 4834 GRALPGLRTYVLDASLHSVPPGTVGELYVSGAQVARGYMGRSALTAERFVADPFTPGTRM 4893
Query: 172 IDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLL 230
TGD+ R NG + + GR D + G++I IE+T+++ P V + V L+ +
Sbjct: 4894 YRTGDLARYRSNGELDHLGRADTQVAVRGYRIEPGEIEATLLRRPDVEHAA-VMLRGSAV 4952
Query: 231 --LIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
+V + + LL +L+ L E P V+ V P +GK + L +
Sbjct: 4953 GDQLVAYVVSAADPRTLLGYLRSVLPEYLVPGAVVPVPAFPLTPNGKLDRHAL----PEP 5008
Query: 289 NILQNVENIKSYLFKELKALVNKDL--NYEDLQSKSFFSLGGTSFLAVTICNKLSLTF 344
+L + +E+ A V +L E +SFF LGG S +A + +LS F
Sbjct: 5009 TVLAADSHAPHGPIEEVVAGVFAELLGGIEVGARQSFFDLGGNSLIATRVAARLSAVF 5066
Score = 59.7 bits (138), Expect = 3e-07
Identities = 87/354 (24%), Positives = 156/354 (44%), Gaps = 29/354 (8%)
Query: 1 MVEILLACTNGASLLIAP-DLT--EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC 57
++E+LLA +GA L++AP D+ L H + +VT + +TPS +
Sbjct: 6710 LLEMLLAFRSGACLVVAPPDVYGGADLQHLLTEQNVTHYLSTPSVLATLEPRKL------ 6763
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
TL+V+A+GGE L+ ++ + + YG TE + A++AE+ + VT G
Sbjct: 6764 --DTLQVVAVGGEALSP----EQAAAWSEGQLMLNAYGPTESTVVATLAEVGAD-VTIG- 6815
Query: 118 KEVPLGNCLSETELFVQPHEKNNT----MGKIILASKTRKCILLNRKNGNKEENSIKFID 173
VP G + + ++P + + LA L N ++ I+
Sbjct: 6816 APVP-GTTATVLDDRLRPVPLGGVGELYLEGLGLALGYVADPALTAANFVAGQSGIRRYR 6874
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLLLI 232
TGD+ R +GT+ Y GR D +K G +I +E+ ++ P V V L L+
Sbjct: 6875 TGDVVHRRVDGTLSYVGRADRQVKVRGMRIEPAEVEAALLVQPGV--TQAVVLLHHGRLV 6932
Query: 233 VYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV--NIYKKSNI 290
+ + + ++ L L +L P +++ D+LP +GK + L +I +N
Sbjct: 6933 AFVTGSAVDAESLRAQLIRQLPAHLVPQRIMIRDSLPLTPNGKLDVQALEANDIDNDTNS 6992
Query: 291 LQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTF 344
+ + + L + A V +++ +FF +GG S A + +LS F
Sbjct: 6993 SEPLRTVTGELVAAVFAAVLGEVSVG--AHSNFFDIGGDSLSATAVTGRLSAAF 7044
Score = 37.5 bits (83), Expect = 1.3
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 9/175 (5%)
Query: 174 TGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP---L 229
TGD + +G + Y GR D ++ G ++ ++ + + VR + P L
Sbjct: 7904 TGDLVRRNAHGALDYLGRDDAQVQLHGIRVEPAEVDVALTRHSDVRFVITTPVVAPGGQL 7963
Query: 230 LLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
+L+ Y E T + + +F + L P V+ +D+LP GK + L
Sbjct: 7964 VLVSYVVMEPDSTHTPHSVREFARAVLPRHLVPSAVVVLDSLPVLPSGKVDRSALPEPEF 8023
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDLQS-KSFFSLGGTSFLAVTICNKL 340
S+ I YL + ++ + + + + + + FF+LGGTS AV ++L
Sbjct: 8024 DSDTPGTTPPI-GYLETVVAEVMAEVIGVDFIGADQDFFALGGTSMGAVAAADEL 8077
>UniRef50_Q0LP26 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1525
Score = 66.9 bits (156), Expect = 2e-09
Identities = 79/331 (23%), Positives = 143/331 (43%), Gaps = 27/331 (8%)
Query: 65 LALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGN 124
L LGGE ++ K+L+ L ++F YG TE + L N + LG
Sbjct: 710 LILGGEAVSW-KLLQTLALLAPDCQVFNHYGPTETTVGVLTNPLSANLPSAQSAIPALGR 768
Query: 125 CLSETELFV-----QPHEKNNT----MGKIILASK--TRKCILLNR--KNGNKEENSIKF 171
++ T++++ QP T +G LA R I R +G + +
Sbjct: 769 PIANTQIYLLDVHGQPVPLGMTGELYVGGAALARGYWQRPAITAERFVPDGLSGQTGSRL 828
Query: 172 IDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL- 229
TGD+ + +G + + GR DD +K G +I L IE+ + + + + P
Sbjct: 829 YRTGDVARYLPDGKLEFLGRADDQVKIRGFRIELGEIEAALRNHTAIEQAAVIVRDDPAG 888
Query: 230 --LLIVYFSA---ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL-VN 283
L+ Y A LS +EL +FLK L + P + ++ LP NA+GK ++ L
Sbjct: 889 DKRLVAYLVAGQQRPLSLRELRNFLKQSLPDYMVPAAFVMLERLPLNANGKLDRQALPAP 948
Query: 284 IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSL 342
+++ + ++ + L + ++ L + + + +FF LGG S L++ I + S
Sbjct: 949 EQQQTKASTQIVAPRTPVETTLVDIWSQVLGGKSVGINNNFFELGGDSILSIQIIARAS- 1007
Query: 343 TFPEVGKHILPHLLSHNKSIGDVLKTITQDT 373
+ G + P L + +I D+ + + T
Sbjct: 1008 ---QAGLKLTPKQLFDHPTIADLAQVVATTT 1035
>UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2;
Firmicutes|Rep: Amino acid adenylation domain - Bacillus
cereus subsp. cytotoxis NVH 391-98
Length = 2031
Score = 66.9 bits (156), Expect = 2e-09
Identities = 62/256 (24%), Positives = 113/256 (44%), Gaps = 20/256 (7%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG-DKEV 120
L+ L GE L I K L+ T + LYG TE S + ++ N++ G + +
Sbjct: 1064 LRWLIFSGEALPASVIKKWLQTYGESTGLANLYGPTEASIDVTYHIIEGNQILDGSENSI 1123
Query: 121 PLGNCLSETELFVQPHEKNNT----MGKIILASKTRKCILLNRKNGNKEENSIKFID--- 173
+G L+ + + + +G++ + LN + KE +
Sbjct: 1124 LIGKPLNNVHVKILDEDMREVPKGIIGELWIGGIQLAKGYLNNPSKTKEAFKMNLFSEIP 1183
Query: 174 ------TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
TGD+ ++R +G + Y GR+D+ +K G ++ L IE+ + V+ V L
Sbjct: 1184 GDYLYRTGDLVKMRPDGNLEYHGRIDNQVKVRGFRVELGEIEAVIHSHSSVKEVGVVTLD 1243
Query: 227 TP---LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
+P LI L QEL F+ KL P ++ + +LP N +GK ++++++
Sbjct: 1244 SPEEHKQLIACVVGNCLEEQELKRFIGQKLPYYMIPHRIEFLSSLPKNHNGKLDRKVMLS 1303
Query: 284 IY--KKSNILQNVENI 297
I KK + Q+V ++
Sbjct: 1304 ILQTKKKEMRQDVSSV 1319
>UniRef50_A3INX3 Cluster: Non-ribosomal peptide synthase/polyketide
synthase; n=1; Cyanothece sp. CCY 0110|Rep: Non-ribosomal
peptide synthase/polyketide synthase - Cyanothece sp. CCY
0110
Length = 1149
Score = 66.9 bits (156), Expect = 2e-09
Identities = 83/339 (24%), Positives = 150/339 (44%), Gaps = 30/339 (8%)
Query: 32 SVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIF 91
+VT W + P+ + E ++N +L++ LGG+ L + + LK N +
Sbjct: 763 NVTLWNSVPT-MMEMLVEYLENSQDSTPKSLRLAILGGDWLP-LSLPNRLKSLINGVTLL 820
Query: 92 TLYGVTEMSCWA---SVAELDLN-------KVTTGDKEVPLGNCLSETELFVQPHEKNNT 141
++ G TE + W V E+D N K K L L + ++V P + T
Sbjct: 821 SIGGPTETTIWNIGYEVQEVDPNWKSIPYGKPMGNSKYYILNERLEDCPIWV-PGQMYCT 879
Query: 142 MGKIILA-----SKTRKCILLNRKNGNKEENSIKFIDTGDIG-EIRNGTVFYRGRVDDTI 195
++ KT++ +++ K G + TGD+G I +G + GRVD I
Sbjct: 880 GVQVAKGYWQHQEKTQERFIIHPKTGER------IYATGDLGCYIPDGNIRILGRVDFQI 933
Query: 196 KRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLL--LIVYFSAETLSSQELLDFLKCKL 253
K GH+I IES + + ++S + L+ +I +F++ +L + + +LK KL
Sbjct: 934 KLRGHRIEPSEIESILFKHLDIKSALVNYSNEKLIAYIIPHFNS-SLEVEGIKSYLKEKL 992
Query: 254 DEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNI-LQNVENIKSYLFKELKALVNKD 312
+ P +++ P +A+GK + L + +N + K+ L K + +
Sbjct: 993 PDYMIPSYFFFLESFPLSANGKIDRLALPQFEEVANSKYDDYVAPKTELEKIISDTWKQV 1052
Query: 313 LNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTFPEVGKH 350
L E + +++FF LGG S L + L + PE K+
Sbjct: 1053 LEVEKIGINRNFFDLGGNSLLITKVYTSLKQSLPENTKN 1091
>UniRef50_Q95Q02 Cluster: Putative uncharacterized protein; n=2;
cellular organisms|Rep: Putative uncharacterized protein
- Caenorhabditis elegans
Length = 2870
Score = 66.9 bits (156), Expect = 2e-09
Identities = 58/240 (24%), Positives = 112/240 (46%), Gaps = 17/240 (7%)
Query: 53 NKILCARS--TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDL 110
++I C S L+ L GGEP +LK++ + R++ +G+TE + +++ +
Sbjct: 978 SRIPCIESLNNLESLQYGGEPC-APHVLKQIFGAHQNLRVWQEFGLTEQTVYSARQRIYP 1036
Query: 111 NKVTTGDKEVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSIK 170
+T+ D +G +L V+ + ++L+ + L R +
Sbjct: 1037 RSLTSLDDLRRIGEPFDNIQLGVEGSQ-------LVLSG-----VGLMRGYFGVTRQPLN 1084
Query: 171 FIDTGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL 229
++TGD + + + G + + GR D +K GH+I+L IE + + SCSCV +
Sbjct: 1085 KLNTGDEVSKRKQGGLIFMGRKDSQVKVRGHRIDLFEIECAALSSNLIDSCSCVVGENCQ 1144
Query: 230 LLIVYFSAETLSSQE-LLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L++ + E +QE L + L+ +L P +++ +D+ P GK K+ LV + S
Sbjct: 1145 LVLFFKENENPDTQEKLKNHLEKELIAYKVPSRLVGLDSFPLTRTGKIDKKKLVELSNAS 1204
Score = 52.0 bits (119), Expect = 6e-05
Identities = 44/176 (25%), Positives = 79/176 (44%), Gaps = 7/176 (3%)
Query: 163 NKEENSIKFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
N++E+ ++ +GD+ I G V + GR D IK G+++ L IE T+ + SC
Sbjct: 2451 NRKES--QWYASGDVCRIEKGVVEFVGRTDTQIKIRGYRVELTEIEKTIESRNGIASCKA 2508
Query: 223 VWLQTPLLLIVYFSA--ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
++ + + V+++ E LSS + + + L+ P +D P + K
Sbjct: 2509 LFDKESQQIHVFYTGELEKLSSNDAREHCERYLEPHKIPSTFNGIDKFPLTGNSKIDTLK 2568
Query: 281 LVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTI 336
L+ + K +++S L +L+N E S FF +GG S L V +
Sbjct: 2569 LMELVKNLPHPTLPNSLESDLSSIWTSLLNCP---EPSPSDHFFLIGGHSLLLVRL 2621
>UniRef50_Q0LP42 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 2883
Score = 66.5 bits (155), Expect = 3e-09
Identities = 73/304 (24%), Positives = 131/304 (43%), Gaps = 34/304 (11%)
Query: 88 TRIFTLYGVTEM---SCWASVAELDLNKVTTGDKEVPLGNCLSETELFV-----QPHEKN 139
TR+ YGVTE SC+ S ++ ++ VP+G + T ++V QP N
Sbjct: 816 TRLINSYGVTEAVIDSCYFSA-----DQPLIAERSVPIGRPFAATAMYVLDQWLQP-VPN 869
Query: 140 NTMGKIILASKTRKCILLNRKNGNKEE---------NSIKFIDTGDIGE-IRNGTVFYRG 189
+G++ LA + L R + E + TGD G + + G
Sbjct: 870 GAIGELYLAGERLASAYLGRPDLTSERFVPDPWGRLAGARMYRTGDRARWTSTGQLEFLG 929
Query: 190 RVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLLLIVYF--SAETLSSQELLD 247
R D IK G +I L IE+ + Q ++ + TP +V + + + L LL
Sbjct: 930 RGDQQIKLRGFRIELGEIETALTQYSSIQHAVALVHTTPHPQLVAYVVTTQALDQPALLQ 989
Query: 248 FLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENI--KSYLFKEL 305
+L+ ++ E P ++ ++ LP +GK ++ L+ + K L E I + + L
Sbjct: 990 WLQTRVPEYMLPSGIVELEQLPLTPNGKVDRKALLGL--KPTQLSATEQIAPEGATEQAL 1047
Query: 306 KALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDV 365
A+ + L + +FF LGG S LA+ + ++ G + P LL +++I +
Sbjct: 1048 AAIWQQVLGQPVGRHANFFGLGGDSILAMQVVSRCR----AAGLGLTPRLLFQHQTIAAL 1103
Query: 366 LKTI 369
+ +
Sbjct: 1104 AQVL 1107
Score = 56.0 bits (129), Expect = 4e-06
Identities = 68/305 (22%), Positives = 129/305 (42%), Gaps = 26/305 (8%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S L+ L GGEPL + L + +++ +YG TE W++ A++ ++ +
Sbjct: 2286 SNLRALC-GGEPLPR-DLAGALLER--VAQVWNMYGPTETCVWSTCAQIT-TELLLNSTQ 2340
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASK-------TRKCILLNR--KNGNKEE 166
+P+G L+ T+ +V ++ +G++ +A R + R +
Sbjct: 2341 LPIGRPLANTQCYVLDAQQQPLPVGALGELYIAGTGVARGYHERPELTEQRFVPDPFSHN 2400
Query: 167 NSIKFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV-- 223
+ + TGD+ RN GT+ GR+D +K G++I L IE+ ++ P V V
Sbjct: 2401 PTARMYRTGDLARYRNDGTLECLGRIDQQVKIRGYRIELGEIETILLAHPSVAQALVVVQ 2460
Query: 224 WLQTPLLLIVYFSAET--LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
T LI Y T ++ + L L +L P ++ ++ P +GK ++ L
Sbjct: 2461 TTATDAQLIAYLIGATPEVAIEPLRQHLALQLPRYMLPSAIVVLNEWPLTPNGKIDRQAL 2520
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLS 341
+ + N + + L +L+ L L ++ F GG S +A+ L+
Sbjct: 2521 PKPWSEQ---PNQQIARDPLELQLQQLWTSVLGHQLGIHDHFLEHGGHSLIAIRFMALLN 2577
Query: 342 LTFPE 346
T +
Sbjct: 2578 PTLEQ 2582
>UniRef50_A6E8C1 Cluster: Amino acid adenylation; n=1; Pedobacter sp.
BAL39|Rep: Amino acid adenylation - Pedobacter sp. BAL39
Length = 1329
Score = 66.5 bits (155), Expect = 3e-09
Identities = 76/294 (25%), Positives = 135/294 (45%), Gaps = 26/294 (8%)
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
+VL GGE L G ++ ++ N+K I YG TE + + ++++ V VP+
Sbjct: 739 RVLMFGGESLPG-DFIQGIRDSNHKCSIVNHYGPTETTIGKLLHIVNMDNVY--QMTVPI 795
Query: 123 GNCLSETELFVQPHEKNN----TMGKIILASK-TRKCILLNR--------KNGNKEENSI 169
G S T ++V N+ G++ + + K L N K+
Sbjct: 796 GKPFSNTVIYVVDKHFNHCPVGVPGELYIGGRGLAKGYLGNPALTDQSFIKDPFATTPEA 855
Query: 170 KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ-- 226
K TGD+ + +G + Y GR+DD IK G++I L I++ ++ V C+ V +
Sbjct: 856 KIYKTGDLVRWLPDGNIQYMGRIDDQIKIRGNRIELGEIQNVLLSHADVLQCAVVVEENQ 915
Query: 227 -TPLLLIVYFSAETLSSQEL-LDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
L Y + +EL + L+ L E P +++D +P A+GK ++++L I
Sbjct: 916 GNEKQLAAYIVQNGVLDKELMIQHLQKSLPEYMIPRMFLQLDQIPLTANGKINRKLLPKI 975
Query: 285 YKKSNILQNVENIKSYLFKELKA-LVNKDLNYEDLQSK-SFFSLGGTSFLAVTI 336
++ + V S +EL A + K L + + +K +FF LGG S +A+ +
Sbjct: 976 EQEEAL---VFVAPSGGDEELIADIWAKCLGLDKVSTKDNFFELGGHSLIAIKV 1026
>UniRef50_A5FQL9 Cluster: Pyrrolo-quinoline quinone precursor; n=3;
Dehalococcoides|Rep: Pyrrolo-quinoline quinone precursor
- Dehalococcoides sp. BAV1
Length = 371
Score = 66.5 bits (155), Expect = 3e-09
Identities = 54/231 (23%), Positives = 103/231 (44%), Gaps = 12/231 (5%)
Query: 526 GVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKN-EFILFGTLSGVCACLHV 584
GV+YI++Y G I + +K V+D + +A N + I F +GV L
Sbjct: 99 GVIYISTYGGKIYAYNQDQGDLKWVYPVTDALPAIVSGIAPNGDKIFFADTNGVVYALSK 158
Query: 585 NTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFS 644
+W+ I+A PV+ + VI + +++ + G +WT+ AK
Sbjct: 159 ADGQKVWEYPTGAKIWASPVV--SGDLVIVPGFDKKVYALDINTGNPVWTFE-AKSPFAI 215
Query: 645 SLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAA 704
+ V +Y GC D N+Y++++T+ S W + +++P I + K + A
Sbjct: 216 APVVDN-----GTVYVGCFDRNMYALDLTD--GSQKWVFASPNWFWASPVIADGK-VFAP 267
Query: 705 STDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKI 755
+ DG +++ + GT + SSP + D+V + + ++S+ I
Sbjct: 268 NLDGNTYILDALTGTQLKVINMTDGVASSPALLGDNVIVATKTGKIFSINI 318
>UniRef50_A3INW8 Cluster: Peptide synthetase; n=3; Chroococcales|Rep:
Peptide synthetase - Cyanothece sp. CCY 0110
Length = 1876
Score = 66.5 bits (155), Expect = 3e-09
Identities = 88/361 (24%), Positives = 164/361 (45%), Gaps = 38/361 (10%)
Query: 2 VEILLACTNGASLLIAPDLTEV----LFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC 57
+E+ L GA ++I T + L + + ++ + Q TP+ + + K K
Sbjct: 689 LELFLPLITGAKVVIVSRQTVIDGVALSQKIDQSNASMMQATPATWQMLIDAGWKGK--- 745
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
LK+L GGE L+ ++KEL K+ + ++ +YG TE + W+ + K+ T D
Sbjct: 746 --KDLKILC-GGEALSKT-LVKELLTKSQE--LWNMYGPTETTVWSMI-----EKIETED 794
Query: 118 KEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE--NSI-- 169
+ +G ++ T++++ + G++ + +NR++ +E NS
Sbjct: 795 N-ITIGRPINNTQIYILDNHLQPVPIGIPGELYIGGDGLARGYVNRRDLTEERFINSPFN 853
Query: 170 ---KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
K TGDI + + NG V Y GR D +K G +I L IES + Q V++ V
Sbjct: 854 PGKKIYKTGDIAKYLPNGKVEYIGRSDYQVKIRGFRIELGEIESQLNQHLGVKNAVVVAK 913
Query: 226 QTPL---LLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
+ L+ Y+ ++ ++ + L DFLK KL + P I + P +GK ++
Sbjct: 914 KEASGINPLVAYYVSQKESNVTDENLRDFLKKKLPDYMMPLVFISLAEFPLTPNGKIDRK 973
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNK 339
L +++ + + KEL ++ + L + FF+LGG S LA + ++
Sbjct: 974 ALPE-PRETFTDKAFTAPHTPTEKELVSIWQEILGVIVGINNDFFALGGHSLLATQVISR 1032
Query: 340 L 340
+
Sbjct: 1033 I 1033
>UniRef50_A1D6D2 Cluster: Nonribosomal peptide synthase GliP2; n=2;
Trichocomaceae|Rep: Nonribosomal peptide synthase GliP2 -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 2202
Score = 66.5 bits (155), Expect = 3e-09
Identities = 48/175 (27%), Positives = 89/175 (50%), Gaps = 8/175 (4%)
Query: 174 TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLLLI 232
TGDIG + +G + Y GR D+ IK G +I+L ++ST+ + + + + LI
Sbjct: 1440 TGDIGRMMEDGNIEYIGREDNQIKLRGFRIDLGEVQSTISRLASAAK-NVALIVSNGNLI 1498
Query: 233 VYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS----KEILVNIYKKS 288
+ + ET+ + L L+ +L + P+++I + TLPT+A+ K + L + K
Sbjct: 1499 AFMTPETIDVRSLAKSLETQLPQYAVPNRIIALATLPTSANNKVDSFALQRYLRDQGKDG 1558
Query: 289 NILQNVENIKSYLFKELKA-LVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLS 341
+++++E + A ++ +DLN + S FF LGG S L + + +S
Sbjct: 1559 AVVEDLETDTQRALAAIWADVLGRDLNQTPISPSDRFFELGGHSLLQIKVAQAIS 1613
Score = 50.0 bits (114), Expect = 2e-04
Identities = 46/181 (25%), Positives = 80/181 (44%), Gaps = 8/181 (4%)
Query: 165 EENSIKFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHS-IESTVMQCPRVRSCSCV 223
E N + TGD G + + GR D +K G INL + +E ++ +V S S
Sbjct: 387 EWNGARIYKTGDYGRRTKHGLQFCGRRDSVVKNRGFLINLEADVEPALLSYDKVDSASAF 446
Query: 224 WLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
Q L+ V T + + L ++L + PD + +D PT +GK + L+
Sbjct: 447 MSQGRLIAFV---TPTSAKEGLREYLTNTVSSFLVPDTIYSLDEFPTTGNGKVDRRGLMR 503
Query: 284 IY--KKSNILQNVENIKSYLFKELKAL--VNKDLNYEDLQSKSFFSLGGTSFLAVTICNK 339
++ ++ + ++E + + L V + + LQ+ SF LGG S AV + +
Sbjct: 504 MHELEQGSDTASLERGLGAVEAVRRGLSHVLRLPESQILQASSFRHLGGHSLAAVMLVSV 563
Query: 340 L 340
L
Sbjct: 564 L 564
>UniRef50_A7IZW1 Cluster: OciA; n=1; Planktothrix agardhii NIVA-CYA
116|Rep: OciA - Planktothrix agardhii NIVA-CYA 116
Length = 3477
Score = 66.1 bits (154), Expect = 3e-09
Identities = 74/301 (24%), Positives = 135/301 (44%), Gaps = 32/301 (10%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ L +GGE I + K +N F YG TE + A+VA + T +++V
Sbjct: 2060 LQSLTVGGEACTAKLITEWSKGRN----FFNAYGPTETTVCATVA-----RFTKDEEKVS 2110
Query: 122 LGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKEE---------N 167
+G + T++++ QP G++ + LNR +E+
Sbjct: 2111 IGRPVPNTQIYILDSYLQP-VPIGVPGELHIGGAGLARSYLNRPELTQEKFIPNPFSNYP 2169
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+ + +G + Y GR+D+ +K G +I L IE+ + Q P+V+S + +
Sbjct: 2170 DSRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIETVLTQNPQVQSSVIIACE 2229
Query: 227 -TP--LLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
TP L+ Y + T + EL FLK KL E P + +++LP +GK +
Sbjct: 2230 DTPGNKRLVAYIVPQKDATPTPNELRQFLKEKLPEYMIPSAFVILESLPLTPNGKIDRRA 2289
Query: 281 LVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNK 339
L + ++ + + L + ++ L + + + +FF LGG S LA + ++
Sbjct: 2290 LPEPEQSYERTDKFILPRNPIEEILVTIWSEGLKVKQVSINDNFFELGGHSLLATQLISR 2349
Query: 340 L 340
+
Sbjct: 2350 I 2350
Score = 59.7 bits (138), Expect = 3e-07
Identities = 74/300 (24%), Positives = 132/300 (44%), Gaps = 32/300 (10%)
Query: 61 TLKVLALGGEPLNGIKILKEL--KHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
+L+++ GGE L I L+ +H + ++ +YG+TE + + L + V +
Sbjct: 3135 SLRLVIFGGESLE-INSLQPWFDRHGDQLPQLVNMYGITETTVHVTYRPLSMADVNSTAS 3193
Query: 119 EV--PLGNC-LSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKE-------ENS 168
+ PL + + + ++QP G++ + LNR E E+S
Sbjct: 3194 VIGRPLPDLQVYLLDQYLQPVPVG-VPGEMYVGGAGVAKGYLNRPELTTERFISSPFEHS 3252
Query: 169 IKFIDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV-RSCSCVWLQ 226
K TGD+ NG + Y GR+D+ +K G +I L IE+ + P++ + VW
Sbjct: 3253 NKLYKTGDLARYWPNGELEYLGRIDNQVKIRGFRIELGEIEALLASHPQIWETVVLVWDD 3312
Query: 227 T--PLLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
T L+ Y + T+ E+ FLK KL + P+ + ++ LP +GK + L
Sbjct: 3313 TAGDKRLVAYIVPQPEITIIIDEIRQFLKAKLPDYMVPNAFVILEALPLTTNGKIDRRAL 3372
Query: 282 ----VNIYKKSNILQN-VENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTI 336
++I K +E I + ++ E+ + +N +FF LGG S LA +
Sbjct: 3373 PPPNLDISDKYVAPSTPIEEILATIWSEVLKVEKVGIN------DNFFELGGHSLLATQL 3426
>UniRef50_Q97V27 Cluster: Medium-chain-fatty-acid--CoA ligase; n=5;
Thermoprotei|Rep: Medium-chain-fatty-acid--CoA ligase -
Sulfolobus solfataricus
Length = 507
Score = 66.1 bits (154), Expect = 3e-09
Identities = 63/232 (27%), Positives = 113/232 (48%), Gaps = 21/232 (9%)
Query: 62 LKVLALGG-EPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELD-LNKVTTGDKE 119
LKV+ GG EP G+ +K+LK KT + +G+TE A+V + D + +++
Sbjct: 272 LKVVVTGGAEPPLGL--IKKLKELGVKT--YHAWGMTETEAIATVNKSDNIERMSEQGYP 327
Query: 120 VPLGN-CLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSIKFIDTGDIG 178
+P L E P + +T G+++ R + + +K + K+ TGD+
Sbjct: 328 IPAFEIALMGPEGNELPWDGKST-GELV----ARGAFVTKKYLNDKSDAQTKWFRTGDVA 382
Query: 179 EIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV------WLQTPLLL 231
I +G+V R+ D IK G I+ +E+ +M +V V W + P+ L
Sbjct: 383 RINPDGSVKVIDRLKDLIKSGGEWISSVDLENAIMSYEKVLEAVVVGVKDERWGERPIAL 442
Query: 232 IVYFSAETLSSQELLDFLKC-KLDEKYW-PDKVIRVDTLPTNAHGKTSKEIL 281
+V ++ E++++LK K+W PDK+I VD++P + GK K+++
Sbjct: 443 VVKKPGMDVNEYEIIEYLKSLNRFPKWWLPDKIIFVDSIPKTSTGKLDKKLV 494
>UniRef50_O68008 Cluster: Bacitracin synthetase 3 (BA3) [Includes:
ATP-dependent isoleucine adenylase (IleA) (Isoleucine
activase); ATP-dependent D-phenylalanine adenylase
(D-PheA) (D-phenylalanine activase); ATP-dependent
histidine adenylase (HisA) (Histidine activase);
ATP-dependent D-aspartate adenylase (D-AspA) (D-aspartate
activase); ATP-dependent asparagine adenylase (AsnA)
(Asparagine activase); Aspartate racemase (EC 5.1.1.13);
Phenylalanine racemase [ATP hydrolyzing] (EC 5.1.1.11)];
n=3; Bacillus|Rep: Bacitracin synthetase 3 (BA3)
[Includes: ATP-dependent isoleucine adenylase (IleA)
(Isoleucine activase); ATP-dependent D-phenylalanine
adenylase (D-PheA) (D-phenylalanine activase);
ATP-dependent histidine adenylase (HisA) (Histidine
activase); ATP-dependent D-aspartate adenylase (D-AspA)
(D-aspartate activase); ATP-dependent asparagine
adenylase (AsnA) (Asparagine activase); Aspartate
racemase (EC 5.1.1.13); Phenylalanine racemase [ATP
hydrolyzing] (EC 5.1.1.11)] - Bacillus licheniformis
Length = 6359
Score = 66.1 bits (154), Expect = 3e-09
Identities = 75/338 (22%), Positives = 148/338 (43%), Gaps = 28/338 (8%)
Query: 60 STLKVLALGGEPLNGIKILKELKHK-NNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
S++K L +GGE L ++ KE+ + ++ I+ YG TE + + D
Sbjct: 5797 SSIKRLIVGGEDLK-TELAKEITERFHHNIEIYNEYGPTETVVGCMIYQYDAG--WDRQV 5853
Query: 119 EVPLGNCLSETELFV----QPHEKNNTMGKIILASKTRKCILLNRKNGNKEE---NSI-- 169
VP+G S +L++ Q + G++ ++ LN+ E+ N
Sbjct: 5854 SVPIGKPASNVQLYILDERQEVQPVGIAGELYISGDGVAKGYLNKPELTSEKFLPNPFLP 5913
Query: 170 --KFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW-- 224
+ TGD+ ++R +G + Y GR+D +K G++I L IE +++ ++ +
Sbjct: 5914 GERMYRTGDLAKMRPDGHIEYLGRIDHQVKIRGYRIELGEIEHQLLRHSDIKEAAVAAKT 5973
Query: 225 -LQTPLLLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
+L Y +E ++ +++ FL +L E P ++++D LP +GK + L
Sbjct: 5974 DQNNDQVLCAYVVSERDITQKDIKTFLAKELPEYMVPSYLLKLDELPLTPNGKVDLKALP 6033
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL- 340
+ + L E + L +++ A+ LN E + + + F +G S ++ ++L
Sbjct: 6034 EPDRSAGALLEYEPPRHELEEKMAAIWEDILNIEQIGINANIFDIGANSLNVMSFVSRLY 6093
Query: 341 -----SLTFPEV-GKHILPHLLSHNKSIGDVLKTITQD 372
+ F ++ K + L K D+LK T D
Sbjct: 6094 AELGFRVPFKDIFSKPTIKELSDFLKHAQDLLKDYTDD 6131
Score = 62.5 bits (145), Expect = 4e-08
Identities = 81/359 (22%), Positives = 149/359 (41%), Gaps = 29/359 (8%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDND----NSVTFWQTTPSKFFQHSNENIKNKILCA 58
+I A NGASL++ T + HE + V+ T + F ++ NI C
Sbjct: 656 DIFGALLNGASLVLIEKETVLNTHELAEVIKKEQVSVMFITTALFNTLADINIG----CL 711
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
K+ LGGE + + K L H + ++ +YG TE + +A+ +N++ +
Sbjct: 712 AKLRKIF-LGGERASIPHVRKVLNHVG-RDKLIHVYGPTESTVYATY--YFINEIDDEAE 767
Query: 119 EVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE-------N 167
+P+G+ L+ T + + G++ +A LNR+ E+
Sbjct: 768 TIPIGSPLANTSVLIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIP 827
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+ + + +G + + GR+D +K G +I L IES + + +
Sbjct: 828 GERLYKTGDLAKWLPDGNIEFIGRIDHQVKIRGFRIELGEIESRLEMHEDINETIVTVRE 887
Query: 227 ----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
P + + +S EL FL KL E P +++D LP +GK ++ L
Sbjct: 888 DEESRPYICAYITANREISLDELKGFLGEKLPEYMIPAYFVKMDKLPLTKNGKVDRKALP 947
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
+ + E ++ ++L A+ L E + FF +GG S A + ++
Sbjct: 948 EPDRTAGAENEYEAPRNETEEKLAAIWRDILKVEKSGINDHFFEMGGHSLKAAAMAARI 1006
Score = 60.1 bits (139), Expect = 2e-07
Identities = 73/299 (24%), Positives = 136/299 (45%), Gaps = 30/299 (10%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ + + GE N ++++ K ++F YG TE S ++ EL + D++V
Sbjct: 3254 LRFVTVAGEGFNE-SLIRQHFEKLPNVKLFNEYGPTENSVCSTRGELRKD-----DEKVV 3307
Query: 122 LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE---NSI----K 170
+G +S ++++ H + T G++ L+ + LNR + E+ N
Sbjct: 3308 IGRPISNHKVYILNHNQQLLPLGTPGELCLSGEGLARGYLNRPDLTLEKFVPNPFAPGES 3367
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL 229
TGD+ + +G + Y GR+D +K G +I L IE+ +++ + + + + +
Sbjct: 3368 MYRTGDLARFLPDGQIEYLGRIDHQVKIRGFRIELGEIENQLLKIEGIDAAAVMAREDQA 3427
Query: 230 ---LLIVYFSAETLSSQELLDFLKCKLDE--KYW-PDKVIRVDTLPTNAHGKTSKEILVN 283
L Y A+ + + D KC L E Y P +++D LP A+GK ++ L
Sbjct: 3428 GGKYLCAYIVADKAAG--VADVRKCLLKELPDYMVPSYFVKLDQLPLTANGKIDRKALPE 3485
Query: 284 IYKKSNILQ-NVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
S I + E ++ ++L ++ L E++ S +FF LGG S A + KL
Sbjct: 3486 --PSSTISEATYEAPRNRTEEKLVSIWEDVLGIENIGISHNFFELGGHSLKAAALTAKL 3542
Score = 55.6 bits (128), Expect = 5e-06
Identities = 72/331 (21%), Positives = 145/331 (43%), Gaps = 25/331 (7%)
Query: 30 DNSVTFWQTTPSKFFQHSNE-NIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKT 88
+N +T+ + TPS F N+ + CA TL+++ LGGE +N + ++ ++
Sbjct: 4261 ENGITYIKLTPSLFNIFVNDPGFSAEKPCA--TLRLVVLGGEMIN-TRDVETFYNQYPDH 4317
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP-LGNCLSETELFVQPHE----KNNTMG 143
+ YG TE + + +D + + KE P +G + T +V G
Sbjct: 4318 VVMNHYGPTETTIGSVFKVIDPEHLDS-FKECPVIGTPIHNTNAYVLDENMKLLPEGVYG 4376
Query: 144 KIILASKTRKCILLNRKNGNKE---ENSI----KFIDTGDIG-EIRNGTVFYRGRVDDTI 195
++ +A +NR + KE EN K TGD+ + +G + GR+D +
Sbjct: 4377 ELCIAGAGVTGGYVNRPDETKEKFIENPFAPHTKMYRTGDLARRLSDGNIELAGRIDTQV 4436
Query: 196 KRFGHKINLHSIESTVMQCPRVRSCSCVWLQT---PLLLIVYFSAET-LSSQELLDFLKC 251
K G++I I++ ++ ++ + L YF+A+ L +++ +L
Sbjct: 4437 KVRGYRIEPEEIKNRLLAHDDIKEAFIAAREDHKGAKQLCAYFTADAELPFEDIRTYLMH 4496
Query: 252 KLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNK 311
+L E P ++++ +P +A+GK L + E ++ ++L + +
Sbjct: 4497 ELPEYMIPSSFVQIEKMPLSANGKIDTAALPE--PQPGKETEYEPPRNETEEKLVQIWEE 4554
Query: 312 DLNYEDLQ-SKSFFSLGGTSFLAVTICNKLS 341
L + + + FF+ GG S A+ + ++LS
Sbjct: 4555 VLGIDKIGITHHFFAAGGDSIKALQMISRLS 4585
Score = 46.4 bits (105), Expect = 0.003
Identities = 41/174 (23%), Positives = 82/174 (47%), Gaps = 6/174 (3%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ----TP 228
TGD+ + +G + + GR+D +K G++I L IE+ +++ ++ + + + +
Sbjct: 1866 TGDLARWLPDGHLEFLGRIDHQVKIRGYRIELGEIENQLLKLDKIDEAAVIARKDDDHSD 1925
Query: 229 LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L S E +S E+ ++L+ +L P +R+D LP ++ K ++ L +
Sbjct: 1926 YLCAYIVSKEDWTSTEISEWLEKELPHYMIPAYFVRLDKLPLTSNDKVDRKALPAPDRHV 1985
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLS 341
E ++ +L + L D+ S FF+ GG S A+ I ++LS
Sbjct: 1986 ATGAVYEAPRNDTEAKLVDIWRDVLGAGDIGISHHFFAAGGDSIKALQIVSRLS 2039
>UniRef50_Q1D3K7 Cluster: Non-ribosomal peptide synthase; n=1;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 1515
Score = 65.7 bits (153), Expect = 4e-09
Identities = 74/329 (22%), Positives = 146/329 (44%), Gaps = 29/329 (8%)
Query: 65 LALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGN 124
L LGGE + +EL+ + RI+ YG TE + L+ ++ + +PL
Sbjct: 720 LILGGEA-TPLAWAEELQAQAPGCRIYNHYGPTETTVGVMTFRLEPSRPFAANNTLPLER 778
Query: 125 CLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRK---------NGNKEENSIK 170
+ T+++V +P T G++ + LNR N +
Sbjct: 779 PIDNTQVYVLDARLRPVAVGMT-GELYVGGAALARGYLNRPDLTAQSFLPNPFSTTPGAR 837
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ--- 226
TGD+ + +GT+ + GR D+ +K G++I L+ + + Q P+VR S + L+
Sbjct: 838 MYRTGDLARHLPDGTLEHLGRADNQVKYHGYRIELNELRHALNQHPQVRD-SVMMLKRDT 896
Query: 227 --TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
+L+ Y S + +L FL +L E+ P+ + + LP +GK + E L ++
Sbjct: 897 NGNEVLVAYYVSRQEQEHAQLRAFLAERLIEEVLPNVYVHLKKLPLTLNGKVNHEALPSL 956
Query: 285 YK-KSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSL 342
+ + + ++ + L + + LN +++ + +FFS+GG S L + + +K
Sbjct: 957 DEARRRQRSQLVAPRTPVEATLADIWCQVLNLKEVSVTDNFFSVGGDSILGILVVSKAD- 1015
Query: 343 TFPEVGKHILPHLLSHNKSIGDVLKTITQ 371
+ G + P L +++I ++ Q
Sbjct: 1016 ---QAGLKLTPRQLFKHQTIAELASVAAQ 1041
>UniRef50_A6LQ10 Cluster: Amino acid adenylation domain; n=1;
Clostridium beijerinckii NCIMB 8052|Rep: Amino acid
adenylation domain - Clostridium beijerinckii NCIMB 8052
Length = 4034
Score = 65.7 bits (153), Expect = 4e-09
Identities = 70/296 (23%), Positives = 135/296 (45%), Gaps = 20/296 (6%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
+L+++ L G+ + + + +++K++ + + +L G TE S W+ ++ +V K +
Sbjct: 1387 SLRLVLLSGDWIP-LTLPEKIKNQFSDAEVISLGGATEASIWSIYYPIE--EVRREWKSI 1443
Query: 121 PLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE-----ENSIKF 171
P G LS +V +E MG++ + LN ++ E + +
Sbjct: 1444 PYGMPLSNQSFYVLNYENQICHIGVMGELCIGGLGLAEGYLNDEDKTTESFINHKELGRL 1503
Query: 172 IDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP-- 228
TGD G + + G + + GR D IK G+++ L IE+ +++ VR+ S V +T
Sbjct: 1504 YKTGDYGVLHKEGYIEFFGRKDQQIKINGYRLELGEIENCILEYEGVRN-SVVVDRTHDN 1562
Query: 229 --LLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
L Y E +S+ EL +++ L + P + VD +P A+GK +++ L
Sbjct: 1563 GRKYLCAYIVGEKEISTTELREYIVELLPDYMVPSYFVMVDEIPLTANGKVNRKELPEPE 1622
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
+ + + +L A+ L + + + SFF LGG S + V I K+
Sbjct: 1623 VSVETEEEYAAPTNEIEVKLTAMWQDLLEVDQISINNSFFELGGNSVMMVQIITKI 1678
Score = 60.9 bits (141), Expect = 1e-07
Identities = 71/305 (23%), Positives = 136/305 (44%), Gaps = 21/305 (6%)
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
A +L+V+ L G+ + + + +++K K + +L G TE S W+ +D +V
Sbjct: 3507 ANESLRVVLLSGDWIP-LTLPEKIKDKFADAEVVSLGGATEASIWSIYYPID--EVNEEW 3563
Query: 118 KEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLN--RKNGNKEENSI-- 169
+P G L+ + +V +EK G++ + + +N K N N
Sbjct: 3564 NSIPYGMPLANQKFYVLNYEKEVCPIGIAGELYIGGEGLAEGYMNDEEKTNNAFINHPDL 3623
Query: 170 -KFIDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV---W 224
+ +TGD G + R G + + GR D IK G+++ L IE+ +++ +++ +
Sbjct: 3624 GRLYNTGDYGVMSREGYIEFLGRKDHQIKIRGYRVELGEIENRILEHQSIKNVVVIDRSH 3683
Query: 225 LQTPLLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L Y ++ +S EL + L + + P + +D +P A+GK ++ L
Sbjct: 3684 SNGRKYLCAYVVSDVDISVGELREHLGKTVPDYMIPSYFVILDKIPLTANGKVDRKALPE 3743
Query: 284 IYKKSNILQNVENI--KSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
+ ++ VE + S + +L + LN E + + +FF LGG S L V + +L
Sbjct: 3744 P-EVDSLETGVEYVAPNSGIETKLAEIWQNLLNAEQVGINDNFFELGGNSVLLVKMHKQL 3802
Query: 341 SLTFP 345
P
Sbjct: 3803 EQEHP 3807
Score = 54.4 bits (125), Expect = 1e-05
Identities = 62/295 (21%), Positives = 130/295 (44%), Gaps = 18/295 (6%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
+L+++ L G+ + + + +++++K + + +L G TE S W+ ++ +V K +
Sbjct: 2448 SLRLVLLSGDWIP-LTLPEKIQNKFSNAEVISLGGATEASIWSIYYPVE--EVQMDWKSI 2504
Query: 121 PLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLN--RKNGNKEENSI---KF 171
P G L+ + +V + K+ +G++ + +N K N N +
Sbjct: 2505 PYGIPLANQKFYVLNYNKDICPVEVIGELYIGGDGLAEGYMNDEEKTNNAFINHPDLGRL 2564
Query: 172 IDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV---WLQT 227
+TGD G + R G + + GR D IK G+++ L I+S +++ +++ V
Sbjct: 2565 YNTGDYGVLHREGYIEFFGRKDQQIKIRGYRVELGEIQSGILEYKGIKNAVVVDKTHENG 2624
Query: 228 PLLLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L Y E +S + ++L+ L + P + VD +P A+GK ++ L
Sbjct: 2625 RKYLCAYIVGEKEVSITGVREYLEELLPDYMVPSYFVMVDEIPLTANGKVDRKALPEPDG 2684
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
+ + + +L + L + + + FF LGG S + V + K+
Sbjct: 2685 NVELGTAYAAPTNEMENKLAVIWQSLLGLDQVGINDGFFELGGNSVMMVQMITKI 2739
>UniRef50_Q13YA9 Cluster: Non-ribosomal peptide synthase, amino acid
adenylation domain; n=1; Burkholderia xenovorans
LB400|Rep: Non-ribosomal peptide synthase, amino acid
adenylation domain - Burkholderia xenovorans (strain
LB400)
Length = 541
Score = 65.3 bits (152), Expect = 6e-09
Identities = 68/303 (22%), Positives = 131/303 (43%), Gaps = 30/303 (9%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHED--NDNSVTFWQTTPS--KFFQHSNENIKNKILCA 58
++ + NGA L + P E +++ ++++T W + PS F Q + ++
Sbjct: 234 DMFVCWANGACLYV-PKTVEPIYNAAFIKEHAITHWSSVPSGAAFMQQFRKLQPDEF--- 289
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
+L+V GGEPL + + L+ N +R+ +YG TE + + E+ + +
Sbjct: 290 -PSLRVTLFGGEPLPRLLVQAWLRAAPN-SRVLNMYGPTETTVACTAFEVTTEFLADPRR 347
Query: 119 EV-PLGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKE------- 165
V PLG L EL + +P + +I + L + GN+
Sbjct: 348 AVMPLGRALPGMELLIVDAALEPVAPGISGELLIGGPQVASGYLSADEPGNRRFISRMYP 407
Query: 166 -ENSIKFIDTGDIG-EIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
++ ++ + D E+ + ++GR+D IK G++I L +E V C + C+ +
Sbjct: 408 GHSASRWYRSADAAREVAGEGIVFQGRLDTQIKIRGNRIELEEVEHVVRSCSQAALCAVI 467
Query: 224 -WLQTPLL----LIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
W LI + + + ++L + +L P +V+ +DTLP N +GK +
Sbjct: 468 AWPVDEAGRAGGLIAFVTQVQGGATQILQACRQRLPAYAVPQRVVMLDTLPLNVNGKVDR 527
Query: 279 EIL 281
L
Sbjct: 528 RAL 530
>UniRef50_A0ZL90 Cluster: Non-ribosomal peptide synthase; n=1;
Nodularia spumigena CCY 9414|Rep: Non-ribosomal peptide
synthase - Nodularia spumigena CCY 9414
Length = 1518
Score = 65.3 bits (152), Expect = 6e-09
Identities = 48/190 (25%), Positives = 98/190 (51%), Gaps = 15/190 (7%)
Query: 161 NGNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRS 219
N + + + TGD+G + +G + + GR+D+ +K G +I L IE+T++Q P+++
Sbjct: 822 NPFSNDTNSRLYKTGDLGRYLPDGNIEFLGRIDNQVKIRGFRIELEEIETTIVQHPQIQQ 881
Query: 220 CSCVWLQ----TPLLL--IVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAH 273
+ + T L+ IV +L+S E+ ++LK KL E P + +D+LP +
Sbjct: 882 AIAIVREDIPGTKRLVAYIVPHQQHSLNSNEIWEYLKHKLPEYMIPAIFVFLDSLPLTPN 941
Query: 274 GKTSKEIL---VNIYKKSNILQNVENIKSYLFKELKALVN-KDLNYEDLQSKSFFSLGGT 329
GK ++ L +++ N I++ L + + ++ + + D +FF+LGG
Sbjct: 942 GKIDRKSLPIPSTVHQSDNFTAPRNPIETALVEIWQQVLRVEKIGIHD----NFFALGGD 997
Query: 330 SFLAVTICNK 339
S +++ I ++
Sbjct: 998 SIISIQIIDQ 1007
>UniRef50_Q7N3S1 Cluster: Complete genome; segment 9/17; n=1;
Photorhabdus luminescens subsp. laumondii|Rep: Complete
genome; segment 9/17 - Photorhabdus luminescens subsp.
laumondii
Length = 916
Score = 64.9 bits (151), Expect = 8e-09
Identities = 73/316 (23%), Positives = 136/316 (43%), Gaps = 37/316 (11%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
TL+ + +G E L+ K+ + H + +YG E + ASV ++ ++ V
Sbjct: 313 TLRQIFIGAESLSR-KLATQCIHTLPNCLLINMYGPAECTINASVFLVNHYPISDEVNSV 371
Query: 121 PLGNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKNGNKEE---------- 166
P+G +S TE F+ H +G+I +A LNR++ ++
Sbjct: 372 PIGKPVSNTEFFILDHHYQLASEYEIGEIYIAGTQVARGYLNRQDLTEKHFLEIAIPPNT 431
Query: 167 NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
I+ TGD+ + G + GR D+ IK G ++ L I++ + +V+ + +
Sbjct: 432 QKIRLYRTGDLAYWDKEGNAHFAGRKDNQIKVRGMRVELEEIKNAIEVIDQVKHAAILAE 491
Query: 226 QTP------LLLIVYFSAETLSSQELLDF-------LKCKLDEKYWPDKVIRVDTLPTNA 272
+ P L + + ET+ Q D L L + PD+ + +DT+P +
Sbjct: 492 KDPQHRSTRLTACIELADETIRQQAKYDITSILRSELSKTLPDYMLPDRFLFLDTMPLTS 551
Query: 273 HGK---TSKEILVNIYKKS-NILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGG 328
GK + ++LV+ S +L + + + L + ++ ED FF+LGG
Sbjct: 552 SGKIDFDTLQVLVSTVSHSPQVLPSTSTETQIVKIWEEVLTRESISTED----DFFALGG 607
Query: 329 TSFLAVTICNKLSLTF 344
S +AV + +L+ F
Sbjct: 608 NSLIAVHLIQRLNEEF 623
>UniRef50_Q2L5R6 Cluster: Putative peptide synthetase; n=1;
Clostridium perfringens|Rep: Putative peptide synthetase
- Clostridium perfringens
Length = 622
Score = 64.9 bits (151), Expect = 8e-09
Identities = 82/347 (23%), Positives = 160/347 (46%), Gaps = 47/347 (13%)
Query: 2 VEILLACTNGASLLIAPDLTEVLF----HEDNDNSVTFWQTTPS--KFFQHSNENIKNKI 55
+E ++A T G ++IA ++T+ F N ++ Q TPS K N N N +
Sbjct: 230 LETIVALTKGLRVIIADEITQKNFKLINRLINKFNIKMIQCTPSQMKILVECN-NTGNTL 288
Query: 56 LCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTT 115
L+ + +GGE I++L +K K K +++ +YG TE + W+S+ E+ T
Sbjct: 289 ----KNLETIMIGGESFE-IELLTSIK-KLTKAKVYNMYGPTETTIWSSIKEV------T 336
Query: 116 GDKEVPLGNCLSETELFVQPHEKNNTM-----GKIILASKTRKCILLNRKNGNKE----- 165
+++ +G + TE FV +E N + G++I++ + +K+ NK
Sbjct: 337 HSEKITIGRPIQNTEYFV-VNECNQCVPLGEEGELIISGLGLAHGYV-KKSHNKSFIDCD 394
Query: 166 -ENSIKFIDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
+F TGD+ + +G + + R+D+ +K GH++ L +E ++ + V+ S V
Sbjct: 395 CVTGNRFYKTGDLVKFDESGEIIFIDRIDNQVKIRGHRVELKEVELSIRKNFSVKDVSVV 454
Query: 224 WLQTPL---LLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
L+ L +L Y + ++ + L +L P ++ LP +GK
Sbjct: 455 PLKNKLDINMLCAYIVCDYDINISNIKAVLSKELPSYMIPSCFAVLERLPYTHNGKLDYI 514
Query: 280 ILVN--------IYKKSNILQNVENIK--SYLFKELKALVNKDLNYE 316
L + + K+N ++ + I+ + + ++LK+LV K N +
Sbjct: 515 SLTDYTFYSKCALVTKNNFIELEDEIQMNNSINEKLKSLVKKAANID 561
>UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8;
Bacteria|Rep: Non-ribosomal peptide synthase - Myxococcus
xanthus (strain DK 1622)
Length = 3906
Score = 64.9 bits (151), Expect = 8e-09
Identities = 91/373 (24%), Positives = 164/373 (43%), Gaps = 45/373 (12%)
Query: 2 VEILLACTNGASLLIAPDLTEV---LFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC- 57
VE++ T G L+I P+ + + +++T Q TPS+ ++ +++ +
Sbjct: 3485 VELVWTLTRGFHLVIHPEERHARRSVAEQIEHHAITHLQCTPSR----ASLLLQSPGMAR 3540
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
A + L+VL LGGE L + EL+ + R+ +YG TE + W++ ++ + T
Sbjct: 3541 ALARLRVLVLGGEALTPA-LAAELRTRLTG-RLLNIYGPTETTIWSTTHAVEASGPT--- 3595
Query: 118 KEVPLGNCLSETELF-VQPHEKNNTM---GKIILASKTRKCILLNR---------KNGNK 164
VP+G +S TE++ V H M G++++ + L+R N
Sbjct: 3596 --VPIGRPVSNTEVYIVDAHGTPVPMGAAGELLIGGEGVSRGYLHRPELTAERFIPNPFS 3653
Query: 165 EENSIKFIDTGDIGEIRNGTVF-YRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
+ TGD + G V + GR+D +K G++I L +E+ + + P +R + V
Sbjct: 3654 SRPGARLYRTGDACRYQPGGVLEFLGRIDQQVKIRGYRIELGEVEAVLREHPALREAAVV 3713
Query: 224 WL---QTPLLLIVYF-------SAETLSS--QELLDFLKCKLDEKYWPDKVIRVDTLPTN 271
L+ Y E L + + FL+ +L E P + ++ LP N
Sbjct: 3714 ARTQDDDAARLVAYLVPSQRDTPLENLQALVAHVRAFLRERLPEYMVPSAFVPLEALPLN 3773
Query: 272 AHGKTSKEILVNIYKKSNILQNVENI--KSYLFKELKALVNKDLNYEDL-QSKSFFSLGG 328
A GK ++ L S Q I L ++ + +DL + + + ++FF LGG
Sbjct: 3774 ASGKVDRQALPQ-PSSSLAEQRPAYIAPAGQLELDIAEVWRQDLRLDVVGRDENFFDLGG 3832
Query: 329 TSFLAVTICNKLS 341
S LA I +L+
Sbjct: 3833 NSLLAARIQARLT 3845
Score = 51.2 bits (117), Expect = 1e-04
Identities = 68/276 (24%), Positives = 118/276 (42%), Gaps = 26/276 (9%)
Query: 87 KTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTM 142
+TR++ LYG TE + V+ D ++ + + VP+G ++ T L+V
Sbjct: 1443 ETRLYNLYGPTEAA--VDVSAWDCHR-SLPSRTVPIGQPVANTALYVLDTRLAPLPVGVP 1499
Query: 143 GKIILASKT-------RKCILLNR--KNGNKEENSIKFIDTGDIGEIR-NGTVFYRGRVD 192
G++ + R + R +G E ++ TGD + +G++ Y GR+D
Sbjct: 1500 GELYIGGVQVGRGYLGRPDLTAERFVPDGFAREEGMRMYRTGDRARVLPDGSLEYLGRLD 1559
Query: 193 DTIKRFGHKINLHSIESTVMQCPRVRSC-----SCVWLQTPLLLIVYFSAETLSSQELLD 247
+K GH+I L IE+T+ Q P V+ + V L+ + + L D
Sbjct: 1560 HQVKVRGHRIELGEIEATLEQHPAVQQAVVLARTAVGDDVQLVAFISHRGHAPTPATLRD 1619
Query: 248 FLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELK- 306
FL +L P + + LP GK + L ++ +++ +E + EL
Sbjct: 1620 FLAERLPGFMVPSHIGILAELPLGPSGKRDRLALASVQVEASD-NGLEWMAPRTPTELTV 1678
Query: 307 ALVNKD-LNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
A + D L E + + FF LGG S LA + +L
Sbjct: 1679 ARIWSDVLKRERIGANDDFFQLGGHSLLATRVVARL 1714
>UniRef50_A5Z788 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 510
Score = 64.9 bits (151), Expect = 8e-09
Identities = 66/283 (23%), Positives = 122/283 (43%), Gaps = 29/283 (10%)
Query: 24 LFHEDNDNSVTFWQTTPS-KFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELK 82
+F + + W +TPS S+ +++ L+V GE L + K L
Sbjct: 228 MFEHFKQSDINVWVSTPSFADMCLSDRKFSGELI---PNLEVFLFCGEVLTTATVSK-LH 283
Query: 83 HKNNKTRIFTLYGVTEMSCWASVAELD---LNKVTTGDKEVPLGNCLSETELFVQPHE-- 137
+ K ++ YG TE + + E+ L + + K +P+G+ T + + +
Sbjct: 284 QRFPKAKVINTYGPTESTVAVTDVEITPELLENIMSQGKSLPVGHEKKGTIIEIHGEQGE 343
Query: 138 --KNNTMGKIILASKTRKCILLNRKNGNK------EENSIKF--IDTGDIGEIRNGTVFY 187
+ G+II+ T R + K E N IK+ TGD G ++ G +FY
Sbjct: 344 ILEEGQQGEIIIIGDTVSTGYYKRDDLTKKAFFQCERNGIKYRAYHTGDAGYLKEGQLFY 403
Query: 188 RGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV--WLQTPLLLIVYFSAETLSSQEL 245
GR+D +K G++I + IE+ +++ P++ + + + F +
Sbjct: 404 NGRIDLQVKLHGYRIEVEDIENNMLRLPQISHAVVLPNIKDGKVKSLTAFVTGDKGEKSD 463
Query: 246 LDF---LKCKLDE---KYW-PDKVIRVDTLPTNAHGKTSKEIL 281
L+F +K +L E Y P K+ VD +P N++GK ++ L
Sbjct: 464 LEFSRQIKTELKEILPAYMVPKKIKYVDNIPMNSNGKADRKYL 506
>UniRef50_A4A1C7 Cluster: Probable serine/threonine protein kinase
related protein; n=1; Blastopirellula marina DSM
3645|Rep: Probable serine/threonine protein kinase
related protein - Blastopirellula marina DSM 3645
Length = 366
Score = 64.9 bits (151), Expect = 8e-09
Identities = 46/185 (24%), Positives = 80/185 (43%), Gaps = 13/185 (7%)
Query: 570 ILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKG 629
+ G L G L++ IW+ S+ + P D Y+ +++G +HC + + G
Sbjct: 66 VYIGDLDGAIYALNLADGKEIWKKSIDTGFYGSPAYRDGKVYL--GDMDGLLHCLSAKTG 123
Query: 630 IKIWTYN-GAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSP 688
+WTY GA+ N +N ++ ++ G D +Y +T L WK ++
Sbjct: 124 DVLWTYETGAEIN-------GSVNFYQDKLLIGSQDATLYC--LTAADGKLVWKYEIADQ 174
Query: 689 VYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRND 748
+ PTI ++ +A D KL +I + G A + T S+P + D V G
Sbjct: 175 IRCMPTIVENRGFVAGC-DSKLHIIDLDKGVSAANVPIDAPTGSTPAVQGDLVVFGTEGG 233
Query: 749 LLYSL 753
LY +
Sbjct: 234 TLYGI 238
Score = 55.6 bits (128), Expect = 5e-06
Identities = 47/267 (17%), Positives = 102/267 (38%), Gaps = 12/267 (4%)
Query: 490 VGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKE 549
+G DG + L + IW+ ++ + Y G +Y+ DG + C+ T +
Sbjct: 68 IGDLDGAIYALNLADGKEIWKKSIDTGFYGSPAYRDGKVYLGDMDGLLHCLSAKTGDVLW 127
Query: 550 TVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDND 609
T + I+ + +++ +L G+ CL ++W+ + I P + +N
Sbjct: 128 TYETGAE-INGSVNFYQDK-LLIGSQDATLYCLTAADGKLVWKYEIADQIRCMPTIVENR 185
Query: 610 KYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQM-YFGCHDNNVY 668
+V A + ++H ++KG+ + N+ + + FG +Y
Sbjct: 186 GFV--AGCDSKLHIIDLDKGV-------SAANVPIDAPTGSTPAVQGDLVVFGTEGGTLY 236
Query: 669 SVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPG 728
++ + S ++ + +L + + ++ + G + G
Sbjct: 237 GIDWKQAKVSWTYEDDRGRQAFRASAAVTAQLAIIGGRNKRVAAVDMTNGKQLWTFPTRG 296
Query: 729 ETFSSPIICDDHVFIGCRNDLLYSLKI 755
SSP+I D V+ G + +Y LKI
Sbjct: 297 RIDSSPVIAGDKVYFGSSDGKVYGLKI 323
Score = 52.8 bits (121), Expect = 3e-05
Identities = 53/272 (19%), Positives = 104/272 (38%), Gaps = 20/272 (7%)
Query: 442 VTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCVHDECVTSPCGVVGTYDGTVICFL 501
V +G G + ++A TG + + + I + D+ + +G+ D T+ C
Sbjct: 106 VYLGDMDGLLHCLSAKTGDVLWTYETGAEINGSVNFYQDKLL------IGSQDATLYCLT 159
Query: 502 LENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISAD 561
+ ++W+ + I+ T + ++A D + ID+ V + S
Sbjct: 160 AADGKLVWKYEIADQIRCMPTIVENRGFVAGCDSKLHIIDLDKGVSAANVPIDAPTGSTP 219
Query: 562 LVLAKNEFILFGTLSGVCACLHVNTKTIIW--QGSLKGPIFACPVLYDNDKYVIFAEVNG 619
V + + ++FGT G + + W + F + I N
Sbjct: 220 AV--QGDLVVFGTEGGTLYGIDWKQAKVSWTYEDDRGRQAFRASAAV-TAQLAIIGGRNK 276
Query: 620 EIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSL 679
+ + G ++WT+ +G I SS + ++YFG D VY + I++ S
Sbjct: 277 RVAAVDMTNGKQLWTF-PTRGRIDSSPVIAGD-----KVYFGSSDGKVYGLKISD--GSA 328
Query: 680 HWKTRVSSPVYSTPTIFNDKLILAASTDGKLW 711
W P + + KL++ AS DG ++
Sbjct: 329 AWSYEAGGSFTGGPAVSDGKLLI-ASDDGNVY 359
Score = 50.0 bits (114), Expect = 2e-04
Identities = 53/265 (20%), Positives = 102/265 (38%), Gaps = 16/265 (6%)
Query: 490 VGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKE 549
+G DG + C + V+W G+ I + + L I S D + C+ +
Sbjct: 108 LGDMDGLLHCLSAKTGDVLWTYETGAEINGSVNFYQDKLLIGSQDATLYCLTAADGKLVW 167
Query: 550 TVHVSDQAISADLVLAKNEFILFGTLSGVCACLHV---NTKTIIWQGSLKGPIFACPVLY 606
++DQ I + +N G ++G + LH+ + + P + P +
Sbjct: 168 KYEIADQ-IRCMPTIVENR----GFVAGCDSKLHIIDLDKGVSAANVPIDAPTGSTPAVQ 222
Query: 607 DNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNN 666
+ V+F G ++ ++ WTY +G + G +
Sbjct: 223 GD--LVVFGTEGGTLYGIDWKQAKVSWTYEDDRGRQAFRASAAVTAQL---AIIGGRNKR 277
Query: 667 VYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQL 726
V +V++TN + + TR + S+P I DK + S+DGK++ + G+ Y+
Sbjct: 278 VAAVDMTNGKQLWTFPTR--GRIDSSPVIAGDK-VYFGSSDGKVYGLKISDGSAAWSYEA 334
Query: 727 PGETFSSPIICDDHVFIGCRNDLLY 751
G P + D + I + +Y
Sbjct: 335 GGSFTGGPAVSDGKLLIASDDGNVY 359
>UniRef50_Q2NHL9 Cluster: Conserved hypothetical membrane-spanning
protein; n=1; Methanosphaera stadtmanae DSM 3091|Rep:
Conserved hypothetical membrane-spanning protein -
Methanosphaera stadtmanae (strain DSM 3091)
Length = 412
Score = 64.9 bits (151), Expect = 8e-09
Identities = 48/169 (28%), Positives = 77/169 (45%), Gaps = 11/169 (6%)
Query: 588 TIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLC 647
T W + G + PVL + Y+ G ++ + G + W Y +G I SS
Sbjct: 51 TQTWTVKVDGAVSTTPVLCGDQIYL--GTDKGTLYALDAQDGNETWKYE-TEGAITSSPT 107
Query: 648 VKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTD 707
V +Y G D +YS N S +WK + + STP I + K I S D
Sbjct: 108 VSGDT-----VYVGSEDGYLYSNNANT--GSNNWKFKSGDRIKSTPAIDSTK-IYVGSDD 159
Query: 708 GKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKID 756
G ++ ++ G+V QY+ SSP++ D ++IG +D +Y+L I+
Sbjct: 160 GYVYALNRNDGSVVWQYKTEDSVESSPVVHGDTLYIGSNDDKVYALNIN 208
Score = 63.7 bits (148), Expect = 2e-08
Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 13/213 (6%)
Query: 545 STIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPV 604
ST TV V D A+S VL ++ L GT G L W+ +G I + P
Sbjct: 50 STQTWTVKV-DGAVSTTPVLCGDQIYL-GTDKGTLYALDAQDGNETWKYETEGAITSSPT 107
Query: 605 LYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHD 664
+ + YV +G ++ G W + G+ S + K +Y G D
Sbjct: 108 VSGDTVYV--GSEDGYLYSNNANTGSNNWKFKS--GDRIKSTPAIDSTK----IYVGSDD 159
Query: 665 NNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQY 724
VY++N + S+ W+ + V S+P + D L + S D K++ ++ G+V Y
Sbjct: 160 GYVYALNRND--GSVVWQYKTEDSVESSPVVHGDTLYIG-SNDDKVYALNINDGSVKWTY 216
Query: 725 QLPGETFSSPIICDDHVFIGCRNDLLYSLKIDT 757
+ SSP I + +V+I ++ +Y+L DT
Sbjct: 217 TTGDDVKSSPAISNGNVYIASEDNQVYALSEDT 249
Score = 62.1 bits (144), Expect = 5e-08
Identities = 54/249 (21%), Positives = 102/249 (40%), Gaps = 15/249 (6%)
Query: 509 WQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKNE 568
W + V + + C +Y+ + G + +D ET + +
Sbjct: 54 WTVKVDGAVSTTPVLCGDQIYLGTDKGTLYALDAQDG--NETWKYETEGAITSSPTVSGD 111
Query: 569 FILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEK 628
+ G+ G + NT + W+ I + P + D+ K + ++ +G ++
Sbjct: 112 TVYVGSEDGYLYSNNANTGSNNWKFKSGDRIKSTPAI-DSTKIYVGSD-DGYVYALNRND 169
Query: 629 GIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSP 688
G +W Y + ++ SS V +Y G +D+ VY++NI + S+ W
Sbjct: 170 GSVVWQYK-TEDSVESSPVVHGDT-----LYIGSNDDKVYALNIND--GSVKWTYTTGDD 221
Query: 689 VYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDH--VFIGCR 746
V S+P I N + + AS D +++ + + G Y + SSP I + H ++IG
Sbjct: 222 VKSSPAISNGNVYI-ASEDNQVYALSEDTGLEVWSYNTGSKVTSSPSIDERHSSLYIGTE 280
Query: 747 NDLLYSLKI 755
LYSL +
Sbjct: 281 QGDLYSLDL 289
Score = 61.7 bits (143), Expect = 7e-08
Identities = 65/302 (21%), Positives = 118/302 (39%), Gaps = 23/302 (7%)
Query: 419 WTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCV 478
W ++T + +SP + S +YV GS G + NANTG K RI++
Sbjct: 94 WKYETEGAITSSPTV--SGDTVYV--GSEDGYLYSNNANTGSNNWKFKSGDRIKST---- 145
Query: 479 HDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNIR 538
+ S VG+ DG V + SV+WQ ++S LYI S D +
Sbjct: 146 --PAIDSTKIYVGSDDGYVYALNRNDGSVVWQYKTEDSVESSPVVHGDTLYIGSNDDKVY 203
Query: 539 CIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGP 598
++I ++K T D S+ + N +I + L +T +W +
Sbjct: 204 ALNINDGSVKWTYTTGDDVKSSPAISNGNVYI--ASEDNQVYALSEDTGLEVWSYNTGSK 261
Query: 599 IFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQM 658
+ + P + + + G+++ + G+K W G+ +S N
Sbjct: 262 VTSSPSIDERHSSLYIGTEQGDLYSLDLRDGLKKWDIE--TGSAINSTPTIFGNNIAVGT 319
Query: 659 YFGCHDNNVYSV----NITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIH 714
G N+Y + NF P + +S + S T+ + + AS DG ++ ++
Sbjct: 320 ASG--STNIYDKFTGNQVWNFNPG--YIPNISGSI-SASTVASGSSLFVASEDGNIYSLN 374
Query: 715 SE 716
++
Sbjct: 375 TD 376
Score = 51.2 bits (117), Expect = 1e-04
Identities = 52/257 (20%), Positives = 104/257 (40%), Gaps = 15/257 (5%)
Query: 490 VGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKE 549
+GT GT+ ++ + W+ I S T +Y+ S DG + + T +
Sbjct: 75 LGTDKGTLYALDAQDGNETWKYETEGAITSSPTVSGDTVYVGSEDGYLYSNNANTGSNNW 134
Query: 550 TVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDND 609
D+ S + + ++ G+ G L+ N +++WQ + + + PV++ +
Sbjct: 135 KFKSGDRIKSTPAIDSTKIYV--GSDDGYVYALNRNDGSVVWQYKTEDSVESSPVVHGDT 192
Query: 610 KYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYS 669
Y+ + +++ + G WTY ++ SS + N +Y DN VY+
Sbjct: 193 LYI--GSNDDKVYALNINDGSVKWTYT-TGDDVKSSPAISNGN-----VYIASEDNQVYA 244
Query: 670 VN-ITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTD-GKLWVIHSELGTVTAQYQLP 727
++ T + W S V S+P+I L T+ G L+ + G +
Sbjct: 245 LSEDTGLEV---WSYNTGSKVTSSPSIDERHSSLYIGTEQGDLYSLDLRDGLKKWDIETG 301
Query: 728 GETFSSPIICDDHVFIG 744
S+P I +++ +G
Sbjct: 302 SAINSTPTIFGNNIAVG 318
Score = 47.6 bits (108), Expect = 0.001
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 2/103 (1%)
Query: 655 KWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIH 714
+W M+ + Y ++F W +V V +TP + D++ L G L+ +
Sbjct: 29 EWPMFQNNPRHTGYVNQDSSFSTQT-WTVKVDGAVSTTPVLCGDQIYLGTDK-GTLYALD 86
Query: 715 SELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKIDT 757
++ G T +Y+ G SSP + D V++G + LYS +T
Sbjct: 87 AQDGNETWKYETEGAITSSPTVSGDTVYVGSEDGYLYSNNANT 129
Score = 44.0 bits (99), Expect = 0.015
Identities = 47/225 (20%), Positives = 86/225 (38%), Gaps = 15/225 (6%)
Query: 370 TQDTNCLENKFK-KSIKRNRSTSSHGENSISYKKGAGGIRNSNTVEFVVQWTFDTGKCVD 428
+ + N N +K KS R +ST + I G + N + V W + T V+
Sbjct: 124 SNNANTGSNNWKFKSGDRIKSTPAIDSTKIYVGSDDGYVYALNRNDGSVVWQYKTEDSVE 183
Query: 429 ASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCVHDECVTSPCG 488
+SP ++ LY +GS+ K+ +N N G ++ +++ +++
Sbjct: 184 SSPVVH--GDTLY--IGSNDDKVYALNINDGSVKWTYTTGDDVKS------SPAISNGNV 233
Query: 489 VVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCK--GVLYIASYDGNIRCIDILTST 546
+ + D V + +W N GS + S + + LYI + G++ +D+
Sbjct: 234 YIASEDNQVYALSEDTGLEVWSYNTGSKVTSSPSIDERHSSLYIGTEQGDLYSLDLRDGL 293
Query: 547 IKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIW 591
K + S + N I GT SG T +W
Sbjct: 294 KKWDIETGSAINSTPTIFGNN--IAVGTASGSTNIYDKFTGNQVW 336
>UniRef50_Q0W804 Cluster: Putative uncharacterized protein; n=1;
uncultured methanogenic archaeon RC-I|Rep: Putative
uncharacterized protein - Uncultured methanogenic
archaeon RC-I
Length = 419
Score = 64.9 bits (151), Expect = 8e-09
Identities = 71/327 (21%), Positives = 126/327 (38%), Gaps = 23/327 (7%)
Query: 419 WTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCV 478
W + G + S ++ +V Y ++ + + TG +Q + + IE
Sbjct: 51 WVNNVGSGIIGSAVIH-GNTVYYANGAGNA--LTAADLATGKVQWIFRTDGSIENTPALA 107
Query: 479 HDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNIR 538
+D V G+YD V + + S++W+ VG + S G +Y + N
Sbjct: 108 NDTLV------FGSYDSHVYRVRISDGSLVWKTPVGDGMYSSPLVYDGRVYAGTDGSNFY 161
Query: 539 CIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGP 598
+D+ T + + + S K + G G L T ++W
Sbjct: 162 ALDLATGNVVWKLERNTTQASPAGDQGK---VFIGMHDGHVYALDAATGNVVWSYDTASQ 218
Query: 599 IFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYN-GAKGNIFSSLCVKEINKFKWQ 657
I A P+++D V A GE+ G +W + G + + S + +
Sbjct: 219 IHASPMIFDGK--VFIATRGGELFAFDEASGAVLWQADLGYRADTTPS-----ADPEQGT 271
Query: 658 MYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSEL 717
+ G + V + + N +L W + P+YST TI D I + DG ++ + E
Sbjct: 272 VVVGTYGGYVKAFHADN--GTLKWASGFYGPMYSTLTISGDS-IYGVTQDGWIFALDRED 328
Query: 718 GTVTAQYQLPGETFSSPIICDDHVFIG 744
G+ L G TF+SP+I + IG
Sbjct: 329 GSGLWGTDLGGVTFASPVIAGGRLVIG 355
Score = 39.1 bits (87), Expect = 0.43
Identities = 37/167 (22%), Positives = 72/167 (43%), Gaps = 12/167 (7%)
Query: 586 TKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSS 645
T + W G I P L ND ++F + ++ + G +W G ++SS
Sbjct: 87 TGKVQWIFRTDGSIENTPALA-NDT-LVFGSYDSHVYRVRISDGSLVWKTPVGDG-MYSS 143
Query: 646 LCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAAS 705
V + ++Y G +N Y++++ ++ WK ++ ++P K+ +
Sbjct: 144 PLV-----YDGRVYAGTDGSNFYALDLAT--GNVVWKLERNT-TQASPAGDQGKVFIGMH 195
Query: 706 TDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYS 752
DG ++ + + G V Y + +SP+I D VFI R L++
Sbjct: 196 -DGHVYALDAATGNVVWSYDTASQIHASPMIFDGKVFIATRGGELFA 241
Score = 37.1 bits (82), Expect = 1.8
Identities = 19/79 (24%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 679 LHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICD 738
+ W R + +TP + ND L+ S D ++ + G++ + + +SSP++ D
Sbjct: 90 VQWIFRTDGSIENTPALANDTLVFG-SYDSHVYRVRISDGSLVWKTPVGDGMYSSPLVYD 148
Query: 739 DHVFIGCRNDLLYSLKIDT 757
V+ G Y+L + T
Sbjct: 149 GRVYAGTDGSNFYALDLAT 167
Score = 35.9 bits (79), Expect = 4.0
Identities = 29/125 (23%), Positives = 52/125 (41%), Gaps = 8/125 (6%)
Query: 417 VQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPIL 476
V W++DT + ASP ++ + V + + G++ + +G + L R +
Sbjct: 209 VVWSYDTASQIHASPMIFDGK----VFIATRGGELFAFDEASGAVLWQADLGYRADTTPS 264
Query: 477 CVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGN 536
++ VVGTY G V F +N ++ W + S T +Y + DG
Sbjct: 265 ADPEQGTV----VVGTYGGYVKAFHADNGTLKWASGFYGPMYSTLTISGDSIYGVTQDGW 320
Query: 537 IRCID 541
I +D
Sbjct: 321 IFALD 325
>UniRef50_Q9A9Q2 Cluster: Medium-chain-fatty-acid--CoA ligase; n=14;
Proteobacteria|Rep: Medium-chain-fatty-acid--CoA ligase
- Caulobacter crescentus (Caulobacter vibrioides)
Length = 1006
Score = 64.5 bits (150), Expect = 1e-08
Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 7/130 (5%)
Query: 159 RKNGNKEENSIKFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV 217
R G K + F DTGD+ I G + R D +K G I+ IE+ + P+V
Sbjct: 409 RGAGGKILDDEGFFDTGDVATIDEYGFMQITDRAKDVVKSGGEWISTIEIENIAVGHPKV 468
Query: 218 RSCSCV------WLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTN 271
+ V W + P+LL+ ET + QE +D+L+ K+ + + PD V+ VD +P
Sbjct: 469 ALAAVVGQPHPKWDERPVLLVKLKEGETAAPQEFIDYLQGKIAKWWMPDDVLIVDDIPLG 528
Query: 272 AHGKTSKEIL 281
A GK K+++
Sbjct: 529 ATGKIDKKLI 538
>UniRef50_Q1Q1C6 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 397
Score = 64.5 bits (150), Expect = 1e-08
Identities = 76/340 (22%), Positives = 145/340 (42%), Gaps = 26/340 (7%)
Query: 416 VVQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPI 475
V++WTF T V +SP + ++ V+Y GS K+ ++ + G ++ + + +E+
Sbjct: 75 VIKWTFQTEGAVTSSPCI-GNDGVIYF--GSKDKKLYAVSRD-GKLKWTFQTQGEVESSP 130
Query: 476 LCVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINV-GSMIKSKATYCKGVLYIASYD 534
D + + G++DG + + S++W+ G +I S A G +Y +D
Sbjct: 131 AVRKDGTI-----LFGSWDGNLYALNADG-SLLWKYAAEGGIISSPAIAPDGTIYFGCWD 184
Query: 535 GNIRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGS 594
+ I +K T +D +S+ + A + + FG+ + K W
Sbjct: 185 KKLHAITS-DGKLKWTQRTADHIVSSPAI-APDGTVCFGSEDYFLFSMTSEGKAS-WSFG 241
Query: 595 LKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKF 654
+ + A P++ N + +E + + + + K WTYN +I SS +
Sbjct: 242 TRYILDASPLIRQNGDICVGSE-DAKFYVFQPDGQAK-WTYNTLY-DIDSSAAIDT---- 294
Query: 655 KWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIH 714
+ +Y G DNN+Y+ L W + S+P + +D +I AS D K++ +
Sbjct: 295 EGNLYVGSGDNNLYAFTPDG---KLKWTYAARGSIRSSPAVTSDNVIYFASGDKKVYAL- 350
Query: 715 SELGTVTAQYQLPGETFSSPII-CDDHVFIGCRNDLLYSL 753
+ + SSP I D V+IG + LY++
Sbjct: 351 DQNSNLKWSITTGDAVESSPCIDKDGTVYIGSNDGKLYAI 390
Score = 49.2 bits (112), Expect = 4e-04
Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 12/184 (6%)
Query: 576 SGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTY 635
+G+ + I W +G + + P + ND + F + +++ + + +K WT+
Sbjct: 63 TGLSPYKSIQNPVIKWTFQTEGAVTSSPCI-GNDGVIYFGSKDKKLYAVSRDGKLK-WTF 120
Query: 636 NGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTI 695
+G + SS V++ + FG D N+Y++N SL WK + S+P I
Sbjct: 121 Q-TQGEVESSPAVRKDGT----ILFGSWDGNLYALNADG---SLLWKYAAEGGIISSPAI 172
Query: 696 FNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIIC-DDHVFIGCRNDLLYSLK 754
D I D KL I S+ G + + SSP I D V G + L+S+
Sbjct: 173 APDGTIYFGCWDKKLHAITSD-GKLKWTQRTADHIVSSPAIAPDGTVCFGSEDYFLFSMT 231
Query: 755 IDTK 758
+ K
Sbjct: 232 SEGK 235
>UniRef50_A5FI49 Cluster: Amino acid adenylation domain; n=1;
Flavobacterium johnsoniae UW101|Rep: Amino acid
adenylation domain - Flavobacterium johnsoniae UW101
Length = 2138
Score = 64.5 bits (150), Expect = 1e-08
Identities = 64/274 (23%), Positives = 119/274 (43%), Gaps = 25/274 (9%)
Query: 86 NKTRIFTLYGVTEMSCWASVAELD--LNKVTTGDKEVPLGNCLSETELFVQPHEKN---- 139
N ++ YG TE + A+ ++ LN V+ G P+ N ++P
Sbjct: 790 NHISVYNTYGPTESTVCATYYHVNEKLNAVSIGK---PIAN---RQVYIIEPESSQLAPV 843
Query: 140 NTMGKIILASKTRKCILLNRKNGNKEE-------NSIKFIDTGDIGE-IRNGTVFYRGRV 191
+G++ ++ K LN+ E+ + TGD+ + +G + Y GR+
Sbjct: 844 GIIGELCISGKGLSAGYLNQPELTAEKFVQNPFIKGERMYRTGDLAYWLPDGNIEYIGRI 903
Query: 192 DDTIKRFGHKINLHSIESTVMQCPR-VRSCSCVWLQT---PLLLIVYFSAETLSSQELLD 247
D +K G +I L IE+ ++Q + VR + +L Y S + + E+
Sbjct: 904 DSQVKIRGFRIELGEIETALLQYSQNVRQAVAAVKEINGEKVLAAYYVSTQEIDKSEIRS 963
Query: 248 FLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKA 307
+L+ KL E P I +D LP +GKT ++ L I + I + ++ + L
Sbjct: 964 YLQGKLPEYMVPGFYIALDVLPLTPNGKTDRKALPEISGEDLIRKEYAAPRNAAEQNLAQ 1023
Query: 308 LVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
+ + L + + + +FF LGG S +A + N++
Sbjct: 1024 IWQEVLGVDQVGITDNFFELGGHSLVAAQVINRI 1057
Score = 62.1 bits (144), Expect = 5e-08
Identities = 83/359 (23%), Positives = 158/359 (44%), Gaps = 31/359 (8%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTL 62
E T G +L + + ++ + +ND +V T PS + + + K +
Sbjct: 1752 EFFFTLTTGKTLRVLKNALDIETYINNDKNVLL-NTVPSVVRKLLEDKVSLK------NI 1804
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
VL + GE L I+ +L + + R LYG +E + + S + L +K G++ + +
Sbjct: 1805 NVLNMAGEILP-TDIIDKLPLEIMEVR--NLYGPSEDTTY-STSYLITSK---GNRTISV 1857
Query: 123 GNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKNGNKEEN-SIKFI----- 172
G +S T+ ++ GK+ L+ + LN+ E+ + F+
Sbjct: 1858 GRPISNTQAWILNESLLPVPVGIAGKLYLSGEGVTRGYLNKPELTAEKFVNNPFVQGGVM 1917
Query: 173 -DTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ---- 226
DTGD+ + +G + + GR D +K G +I L IE+ V V +
Sbjct: 1918 YDTGDLAYWLPDGNIEFLGRKDHQVKIRGFRIELGEIETAVSNYSSTVKQVVVDTKEIES 1977
Query: 227 TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
T +L Y ++E ++ EL L+ L E P I+++ +P +GK ++ L + +
Sbjct: 1978 TQVLAAYYTASENINKGELRKHLQSVLPEFMVPGYFIQLENMPLTPNGKIDRKALPEVSE 2037
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
K I + K+ + K L + + L + + + +FF LGG S +A + N+++ F
Sbjct: 2038 KHIIKKEYVAPKTKIEKSLVTIWQEVLKVDRIGITDNFFELGGHSLMAGQLINRVNKQF 2096
>UniRef50_O76858 Cluster: Ebony protein; n=18; Diptera|Rep: Ebony
protein - Drosophila melanogaster (Fruit fly)
Length = 879
Score = 64.5 bits (150), Expect = 1e-08
Identities = 55/248 (22%), Positives = 110/248 (44%), Gaps = 21/248 (8%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKT-RIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
L++ GEPL+ + + R++ YG TE+ + + K + V
Sbjct: 308 LQIWVCSGEPLSVSLASSFFDYFDEGVHRLYNFYGSTEVLGDVTYFACESKKQLSLYDNV 367
Query: 121 PLGNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKNGNK--------EENS 168
P+G LS T +++ + KN +G+I + +N ++ + E+
Sbjct: 368 PIGIPLSNTVVYLLDADYRPVKNGEIGEIFASGLNLAAGYVNGRDPERFLENPLAVEKKY 427
Query: 169 IKFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL--- 225
+ TGD G ++NG++ Y GR D +K GH+++L +E V + P V +
Sbjct: 428 ARLYRTGDYGSLKNGSIMYEGRTDSQVKIRGHRVDLSEVEKNVAELPLVDKAIVLCYHAG 487
Query: 226 QTPLLLIVYF----SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
Q ++ + A ++ ++ LK KL + Y +V+ ++ +P +GK ++ L
Sbjct: 488 QVDQAILAFVKLRDDAPMVTETQMEARLKDKLAD-YMTPQVVILEHVPLLVNGKVDRQAL 546
Query: 282 VNIYKKSN 289
+ Y+ +N
Sbjct: 547 LKTYETAN 554
>UniRef50_O30409 Cluster: Tyrocidine synthetase 3 (Tyrocidine
synthetase III) [Includes: ATP- dependent asparagine
adenylase (AsnA) (Asparagine activase); ATP- dependent
glutamine adenylase (GlnA) (Glutamine activase); ATP-
dependent tyrosine adenylase (TyrA) (Tyrosine activase);
ATP-dependent valine adenylase (ValA) (Valine activase);
ATP-dependent ornithine adenylase (OrnA) (Ornithine
activase); ATP-dependent leucine adenylase (LeuA)
(Leucine activase)]; n=8; cellular organisms|Rep:
Tyrocidine synthetase 3 (Tyrocidine synthetase III)
[Includes: ATP- dependent asparagine adenylase (AsnA)
(Asparagine activase); ATP- dependent glutamine adenylase
(GlnA) (Glutamine activase); ATP- dependent tyrosine
adenylase (TyrA) (Tyrosine activase); ATP-dependent
valine adenylase (ValA) (Valine activase); ATP-dependent
ornithine adenylase (OrnA) (Ornithine activase);
ATP-dependent leucine adenylase (LeuA) (Leucine
activase)] - Brevibacillus parabrevis
Length = 6486
Score = 64.5 bits (150), Expect = 1e-08
Identities = 59/236 (25%), Positives = 110/236 (46%), Gaps = 22/236 (9%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ + LGGE + +++++ K N I YG TE S A+ ++ D +
Sbjct: 2796 LQTVTLGGEKITA-QLVEKCKQLNPDLVIVNEYGPTESSVVAT-----WQRLAGPDAAIT 2849
Query: 122 LGNCLSETELFV--QPHEKN--NTMGKIILASKTRKCILLNRKNGNKEE-------NSIK 170
+G ++ T L++ Q H+ +G+I + + N+ +E+ +
Sbjct: 2850 IGRPIANTSLYIVNQYHQLQPIGVVGEICIGGRGLARGYWNKPALTEEKFVSHPFAAGER 2909
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL 229
TGD+G+ + +GT+ Y GR+D+ +K G++I + IES ++ ++ + V + L
Sbjct: 2910 MYKTGDLGKWLPDGTIEYIGRIDEQVKVRGYRIEIGEIESALLAAEKLTAAVVVVYEDQL 2969
Query: 230 ---LLIVYFSA-ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
L YF+A E L +L L +L P +++D LP +GK K+ L
Sbjct: 2970 GQSALAAYFTADEQLDVTKLWSHLSKRLPSYMIPAHFVQLDQLPLTPNGKVDKKAL 3025
Score = 62.9 bits (146), Expect = 3e-08
Identities = 87/379 (22%), Positives = 164/379 (43%), Gaps = 36/379 (9%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ + LGGE L ++++++ K K+ I YG TE S +++ + G + +
Sbjct: 5917 LRCVTLGGEKLP-VQLVQKTKEKHPAIEINNEYGPTENSVVTTISR----SIEAG-QAIT 5970
Query: 122 LGNCLSETELFV---QPH-EKNNTMGKIILASKTRKCILLNRKNGNKEE---NSIK---- 170
+G L+ ++++ Q H + +G++ + LN+ E+ N +
Sbjct: 5971 IGRPLANVQVYIVDEQHHLQPIGVVGELCIGGAGLARGYLNKPELTAEKFVANPFRPGER 6030
Query: 171 FIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL 229
TGD+ + R +GT+ Y GR D+ +K G++I + IES V+ + V
Sbjct: 6031 MYKTGDLVKWRTDGTIEYIGRADEQVKVRGYRIEIGEIESAVLAYQGIDQAVVVARDDDA 6090
Query: 230 ----LLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
L YF A T +S L L +L P + +D LP +A+GK ++ L
Sbjct: 6091 TAGSYLCAYFVAATAVSVSGLRSHLAKELPAYMIPSYFVELDQLPLSANGKVDRKALPKP 6150
Query: 285 YKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLT 343
+ + ++ ++L A+ + L E + + FF LGG S A + K+
Sbjct: 6151 QQSDATTREYVAPRNATEQQLAAIWQEVLGVEPIGITDQFFELGGHSLKATLLIAKV--- 6207
Query: 344 FPEVGKHILPHLLSHNKSIGDVLKTITQDTNCLENKFKKSIKRNRSTSSH-------GEN 396
+ + + +L+ +I V IT E+++ +I N+ T+ + G
Sbjct: 6208 YEYMQIELPLNLIFQYPTIEKVADFITHKR--FESRYGTAILLNQETARNVFCFTPIGAQ 6265
Query: 397 SISYKKGAGGIRNSNTVEF 415
S+ Y+K A I+ + F
Sbjct: 6266 SVYYQKLAAEIQGVSLYSF 6284
Score = 58.4 bits (135), Expect = 7e-07
Identities = 71/280 (25%), Positives = 119/280 (42%), Gaps = 26/280 (9%)
Query: 19 DLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKIL 78
D +V+ DN V + TP+ E+I K S+++ +GGE L K+
Sbjct: 680 DKVQVILDIIKDNKVGIIKLTPTHL--KLIEHIDGKA----SSIRRFIVGGENLP-TKLA 732
Query: 79 KEL-KHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHE 137
K++ H +IF YG TE + D TT + VP+G +L++
Sbjct: 733 KQIYDHFGENVQIFNEYGPTETVVGCMIYLYDPQ--TTTQESVPIGVPADNVQLYLLDAS 790
Query: 138 KN----NTMGKIILASKTRKCILLNRKNGNKEE-------NSIKFIDTGDIGE-IRNGTV 185
++G++ +A NR KE+ K TGD+ + + +G +
Sbjct: 791 MQPVPVGSLGEMYIAGDGVAKGYFNRPELTKEKFIDNPFRPGTKMYRTGDLAKWLPDGNM 850
Query: 186 FYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL---LLIVYFSAE-TLS 241
Y GR+D +K GH+I + IE+ + Q V+ + + +L Y +E L+
Sbjct: 851 EYAGRMDYQVKIRGHRIEMGEIETRLTQHEAVKEAVVIVEKDESGQNVLYAYLVSERELT 910
Query: 242 SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
EL +FL L P IR+ +P A+GK ++ L
Sbjct: 911 VAELREFLGRTLPSYMIPSFFIRLAEIPLTANGKVERKKL 950
Score = 58.0 bits (134), Expect = 9e-07
Identities = 85/358 (23%), Positives = 147/358 (41%), Gaps = 30/358 (8%)
Query: 7 ACTNGASLLIAPDLTEV----LFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTL 62
A G L+I P+ ++ L+ + +T ++ TP+ + +N++ ++ L
Sbjct: 4813 ALLTGGQLVICPNGVKMDPASLYETIRRHEITIFEATPALIMPLMHYVYENELDMSQMKL 4872
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWAS-VAELDLNKVTTGDKEVP 121
+L P K L L K RI YGVTE S E D+ + +G VP
Sbjct: 4873 LILGADSCPAEDFKTL--LARFGQKMRIINSYGVTEACIDTSYYEETDVTAIRSG--TVP 4928
Query: 122 LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE---NSI----K 170
+G L ++V N +G++ + LNR +E+ N +
Sbjct: 4929 IGKPLPNMTMYVVDAHLNLQPVGVVGELCIGGAGVARGYLNRPELTEEKFVPNPFAPGER 4988
Query: 171 FIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ--- 226
TGD+ + R +G V + GR D +K G +I L IE+ + + + V +
Sbjct: 4989 LYRTGDLAKWRADGNVEFLGRNDHQVKIRGVRIELGEIETQLRKLDGITEAVVVAREDRG 5048
Query: 227 TPLLLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
L Y A+ L + EL L +L + P + +D LP A+GK + L
Sbjct: 5049 QEKELCAYVVADHKLDTAELRANLLKELPQAMIPAYFVTLDALPLTANGKVDRRSLP--A 5106
Query: 286 KKSNILQNVENI--KSYLFKELKALVNKDLNYEDLQS-KSFFSLGGTSFLAVTICNKL 340
+L+ E + +S L + + LN + + FF+LGG S A+ + + +
Sbjct: 5107 PDVTMLRTTEYVAPRSVWEARLAQVWEQVLNVPQVGALDDFFALGGHSLRAMRVLSSM 5164
Score = 54.0 bits (124), Expect = 1e-05
Identities = 86/368 (23%), Positives = 163/368 (44%), Gaps = 41/368 (11%)
Query: 3 EILLACTNGASL-LIAPDL---TEVLFHEDNDNSVT-FWQTTPSKFFQHSNENIKNKILC 57
EI A +GASL L++ D+ E L N +T W T+P F Q S +N
Sbjct: 3772 EIFGALLHGASLYLVSKDVLLDAEKLGDFLRTNQITTMWLTSPL-FNQLSQDNP-----A 3825
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
+L+ L +GGE L+ K + +K I+ YG TE + +++ ++ + +
Sbjct: 3826 MFDSLRALIVGGEALSP-KHINRVKSALPDLEIWNGYGPTENTTFSTCYLIEQHF----E 3880
Query: 118 KEVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCIL---LNRKNGNKEE-NSIKFID 173
+++P+G ++ + ++ + NN I + + C+ + R NK E + KF+
Sbjct: 3881 EQIPIGKPIANSTAYIV--DGNNQPQPIGVPGEL--CVGGDGVARGYVNKPELTAEKFVP 3936
Query: 174 -----------TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
TGD+ + +GT+ Y GR+D +K G++I L IE+ + Q +V+
Sbjct: 3937 NPFAPGETMYRTGDLARWLPDGTIEYLGRIDQQVKIRGYRIELGEIETVLSQQAQVKEAV 3996
Query: 222 CVWLQT---PLLLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
++ L YF E + + EL + + +L P ++++ LP A+GK
Sbjct: 3997 VAVIEEANGQKALCAYFVPEQAVDAAELREAMSKQLPGYMVPAYYVQMEKLPLTANGKVD 4056
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTI 336
+ L + ++ +L+ + + L + +FF +GG S A+ +
Sbjct: 4057 RRALPQPSGERTTGSAFVAAQNDTEAKLQQIWQEVLGIPAIGIHDNFFEIGGHSLKAMNV 4116
Query: 337 CNKLSLTF 344
++ TF
Sbjct: 4117 ITQVHKTF 4124
Score = 52.4 bits (120), Expect = 4e-05
Identities = 73/308 (23%), Positives = 132/308 (42%), Gaps = 30/308 (9%)
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
A ++L+ + GGE L + + ++ + ++ LYG TE + A+ + +
Sbjct: 1753 ACTSLQRVFCGGEALTPALVSRF--YETQQAQLINLYGPTETTIDATYWPCPRQQEYSA- 1809
Query: 118 KEVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCIL---LNRKNGNKEE-NSIKFID 173
+P+G + L+V +N + + +A + CI L R +EE F+D
Sbjct: 1810 --IPIGKPIDNVRLYVV--NASNQLQPVGVAGEL--CIAGDGLARGYWQREELTKASFVD 1863
Query: 174 -----------TGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
TGD + + +G + Y GR+D +K GH+I L IE+T++Q V++
Sbjct: 1864 NPFEPGGTMYRTGDMVRYLPDGHIEYLGRIDHQVKIRGHRIELGEIEATLLQHEAVKAVV 1923
Query: 222 CVWLQT---PLLLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ Q L Y AE + + EL +L L P + ++ LP +A+GK
Sbjct: 1924 VMARQDGKGQNSLYAYVVAEQDIQTAELRTYLSATLPAYMVPSAFVFLEQLPLSANGKVD 1983
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTI 336
++ L + ++ +L A+ L E + FF LGG S A+ +
Sbjct: 1984 RKALPQPEDAAASAAVYVAPRNEWEAKLAAIWESVLGVEPIGVHDHFFELGGHSLKAMHV 2043
Query: 337 CNKLSLTF 344
+ L +F
Sbjct: 2044 ISLLQRSF 2051
>UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C
[Includes: ATP-dependent valine adenylase (ValA) (Valine
activase); ATP-dependent D-valine adenylase (D-ValA)
(D-valine activase); Valine racemase [ATP-hydrolyzing]
(EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA)
(Tryptophan activase); ATP-dependent D-leucine adenylase
(D-LeuA) (D-leucine activase); Leucine racemase
[ATP-hydrolyzing] (EC 5.1.1.-); ATP- dependent
tryptophan/phenylalanine/tyrosine adenylase
(Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine
activase); ATP-dependent D-leucine adenylase (D-LeuA)
(D-leucine activase); Leucine racemase [ATP- hydrolyzing]
(EC 5.1.1.-)]; n=11; cellular organisms|Rep: Linear
gramicidin synthetase subunit C [Includes: ATP-dependent
valine adenylase (ValA) (Valine activase); ATP-dependent
D-valine adenylase (D-ValA) (D-valine activase); Valine
racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent
tryptophan adenylase (TrpA) (Tryptophan activase);
ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine
activase); Leucine racemase [ATP-hydrolyzing] (EC
5.1.1.-); ATP- dependent
tryptophan/phenylalanine/tyrosine adenylase
(Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine
activase); ATP-dependent D-leucine adenylase (D-LeuA)
(D-leucine activase); Leucine racemase [ATP- hydrolyzing]
(EC 5.1.1.-)] - Brevibacillus parabrevis
Length = 7756
Score = 64.5 bits (150), Expect = 1e-08
Identities = 50/217 (23%), Positives = 100/217 (46%), Gaps = 13/217 (5%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP---- 228
TGD+ + +G + + GR+D+ +K G +I L IE+ +++ P V+ + +
Sbjct: 1912 TGDLVRYLPDGAIEFIGRIDNQVKIRGFRIELGEIETALLRHPAVQEAFLMVREDAPGDK 1971
Query: 229 --LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL-VNIY 285
+V+ +T+ E+ +LK KL E P +++D+ P +GK + L Y
Sbjct: 1972 RLAAYLVFAGGQTVEPVEMRSYLKDKLPEYMIPSAFVQMDSFPLTPNGKVDRRALPTPEY 2031
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
+S + L +L + L D+ +FF LGG S L++ I + +
Sbjct: 2032 ARSEAASGYVAPATELEVKLADIWKTVLGVADVGIHDNFFELGGDSILSIQIVARAN--- 2088
Query: 345 PEVGKHILPHLLSHNKSIGDVLKTITQDTNCLENKFK 381
++G + P L N++I ++L+ + + K++
Sbjct: 2089 -QLGIRLTPKQLFENQTIAELLRVVADSSQLPHTKWE 2124
Score = 51.6 bits (118), Expect = 8e-05
Identities = 52/218 (23%), Positives = 96/218 (44%), Gaps = 16/218 (7%)
Query: 170 KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV----- 223
K TGD+ + +G + + GR DD + G ++ L IES + Q P V+ +
Sbjct: 7068 KMYRTGDLVRYLPDGQIEFIGRSDDQVSIRGFRVELGEIESVLYQHPAVKEAIVLAREDM 7127
Query: 224 -WLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL- 281
++ +V + + +L +LK KL E P + + LP +GK + L
Sbjct: 7128 PGVKRLAAYVVVAEDDAEQADDLRGYLKEKLPEYMVPAAFVTLKALPLTPNGKVDRRALP 7187
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
V Y ++ ++++ K L + + L E++ +FF LGG S L++ I +
Sbjct: 7188 VPEYTAAD--GEYVAPETFVEKVLAQIWKEVLGVEEVGIHDNFFELGGDSILSIQIVARA 7245
Query: 341 SLTFPEVGKHILPHLLSHNKSIGDVLKTITQDTN-CLE 377
+ G + P LL N++I ++ + + C E
Sbjct: 7246 G----QSGIRLSPKLLFENQTIAELSHAVGDSVHICAE 7279
Score = 49.2 bits (112), Expect = 4e-04
Identities = 30/110 (27%), Positives = 54/110 (49%), Gaps = 2/110 (1%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV-WLQTPLLL 231
TGD+ + +G + + GR+D +K G++I L IES + Q P ++ + W Q
Sbjct: 3432 TGDLVRYLPDGNLEFLGRIDTQVKIRGYRIELGEIESALSQHPAIQEAVVIAWEQRLAAY 3491
Query: 232 IVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
+V +++EL +LK L + P + +D +P +GK + L
Sbjct: 3492 MVAAGEAQPAAEELARYLKETLPDYMIPAGFVFMDAIPLTVNGKVDRRAL 3541
Score = 48.4 bits (110), Expect = 7e-04
Identities = 44/180 (24%), Positives = 82/180 (45%), Gaps = 9/180 (5%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT---PL 229
TGD+ + NGT+ + GR+D+ +K G +I L +E+ + P V + +
Sbjct: 847 TGDLVRYLPNGTIEFIGRIDNQVKIRGFRIELGEVEAALALHPEVSETVVMARENDRGEK 906
Query: 230 LLIVYFSAETLSSQELLD---FLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN-IY 285
L Y + + E+ D +LK KL E P + +D +P A+GK + L +
Sbjct: 907 HLTAYVTVAKDDAPEVADLQAWLKTKLPEYMVPSAYVFLDAMPLTANGKIDRRRLPEPEW 966
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
+ + ++ + + ++ ++ L E + +FF LGG S LA + ++L F
Sbjct: 967 GNRSETKAYTEPRNQAEELIASIWSQVLGVEKVGIHDNFFELGGHSLLATRVISRLREVF 1026
Score = 48.4 bits (110), Expect = 7e-04
Identities = 51/185 (27%), Positives = 84/185 (45%), Gaps = 19/185 (10%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT---PL 229
TGD+ + NG + + GR+DD +K G++I L IE+ + Q P V++ + Q
Sbjct: 6011 TGDLVRYLENGELEFLGRIDDQVKIRGYRIELGEIENALRQHPAVQNVVVIARQEGAGDK 6070
Query: 230 LLIVYFSAET---LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L Y A T EL+ +LK L E P + ++ +P +GK + L
Sbjct: 6071 RLAAYLVAATGQQPDEAELVRYLKSTLPEYMVPAGYVWLEKIPLTVNGKVDRRAL----- 6125
Query: 287 KSNILQNVENIKSYLF--KELKALV----NKDLNYEDL-QSKSFFSLGGTSFLAVTICNK 339
+ + E K+Y+ K ++ +V + L+ E + FF LGG S LA ++
Sbjct: 6126 PAPDYGHAETGKAYVAPRKPIEEIVANIWAQVLSVERVGVYDDFFELGGHSLLATQAVSR 6185
Query: 340 LSLTF 344
L F
Sbjct: 6186 LKEAF 6190
Score = 37.5 bits (83), Expect = 1.3
Identities = 49/215 (22%), Positives = 95/215 (44%), Gaps = 28/215 (13%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR-SCSCVWLQTPLL- 230
TGD+ + +G + + GR DD + G ++ L IE+ + P V+ + V P +
Sbjct: 4488 TGDLVRYLPDGNIEFIGRADDQVSIRGFRVELGEIETALYSHPAVKETIVLVREDMPGMK 4547
Query: 231 -LIVYF------SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV- 282
L+ Y + + + + +LK L E P + + LP +GK + L
Sbjct: 4548 RLVAYIVQREGQEGQAVQAGDFRSYLKELLPEYMVPAAFVFMADLPLTPNGKVDRRALPA 4607
Query: 283 -NIYKK----SNILQNVE-NIK-SYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVT 335
+++ + + E IK ++++K + L D+ D +FF LGG S L++
Sbjct: 4608 PDLFNSEADGTYVAPATELEIKLAHIWKNVLGLA--DVGIHD----NFFELGGDSILSIQ 4661
Query: 336 ICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTIT 370
I ++ + + G + P L N++I ++ T
Sbjct: 4662 IVSRAN----QAGIRLTPKQLLANQTIAELASVAT 4692
>UniRef50_UPI000038CB2F Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal
peptide synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 918
Score = 64.1 bits (149), Expect = 1e-08
Identities = 57/228 (25%), Positives = 111/228 (48%), Gaps = 14/228 (6%)
Query: 161 NGNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRS 219
N E + TGD+ + +G + + GR+DD +K G +I L IE+ + Q P +
Sbjct: 411 NPFSSEPGARLYKTGDLARYLSDGNIEFLGRIDDQVKIRGFRIELGEIEAILGQHPALTQ 470
Query: 220 CSCVWLQT-----PLLLIVYFSAETLSSQ-ELLDFLKCKLDEKYWPDKVIRVDTLPTNAH 273
+ L+ + SAE + S+ EL FL+ +L E P + +DTLP N +
Sbjct: 471 TLVIARDDVNGDKQLVAYIVASAEQIPSRVELRRFLQSQLPEYMVPAYFVFLDTLPLNPN 530
Query: 274 GKTSKEIL--VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTS 330
GK + L ++ ++ + + V ++ + +E+ + + L + + K +FF +GG S
Sbjct: 531 GKIDRRALPAPDLSRRESEVTFVAP-RNEVEREITQIWEQILGVQPIGVKDNFFEIGGNS 589
Query: 331 FLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQDTNCLEN 378
LAV + ++ F K++ +L + ++ + K I+Q+ + + N
Sbjct: 590 ILAVKLFWQIEKIF---SKNLPLAILFQSGTVEALAKIISQEEDLVRN 634
>UniRef50_Q3M3K2 Cluster: Amino acid adenylation; n=2;
Nostocaceae|Rep: Amino acid adenylation - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 1093
Score = 64.1 bits (149), Expect = 1e-08
Identities = 89/365 (24%), Positives = 160/365 (43%), Gaps = 35/365 (9%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTL 62
EI NG L+I P T L ++ + + Q T I ++ + A L
Sbjct: 685 EIWGCLLNGGKLVIFPPNTPSL--DELEQIIQQHQVTTLWLTAGLFHLIVDEKIDALKPL 742
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
+ L GG+ L+ + K L N ++ YG TE + + D+ +P+
Sbjct: 743 RQLLAGGDVLSVSHVQKFLSTVEN-CKLINGYGPTENTTFTCC--YDITAPLKPGASIPI 799
Query: 123 GNCLSETELFV-----QPHEKNNT----MGKIILASK-------TRKCILLNRKNGNKEE 166
G ++ +++++ QP T +G LA + T + +L+ N + +
Sbjct: 800 GRPIANSQVYILDSHLQPVPIGVTGELYIGGDGLAREYFHRPDLTAERFILHPFNSDPQS 859
Query: 167 NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW- 224
K +GD+ + +G + Y GR+D+ +K G +I L IE +Q P V+ V
Sbjct: 860 RLYK---SGDLARYLPDGEIEYLGRIDNQVKVSGFRIELGEIEIAFLQHPAVKEAVVVVR 916
Query: 225 --LQTPLLLIVYFSAET----LS-SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ LL+ YF AET LS EL FLK +L E P + ++ LP NA+GK
Sbjct: 917 EDIPGEKLLVGYFVAETGQDNLSIISELRQFLKQQLPEYMVPKVFMALEALPLNANGKVD 976
Query: 278 KEILVN-IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVT 335
+ +L + + N ++ + +++ + + LN + + +FF LGG S + +
Sbjct: 977 RRVLPKPDSSRPELEANYVAPRTPIEQQIADIWTQVLNIKRVGIYDNFFELGGYSLVGIQ 1036
Query: 336 ICNKL 340
+ ++L
Sbjct: 1037 VISRL 1041
>UniRef50_Q6E7J8 Cluster: JamL; n=4; Bacteria|Rep: JamL - Lyngbya
majuscula
Length = 3935
Score = 64.1 bits (149), Expect = 1e-08
Identities = 64/245 (26%), Positives = 115/245 (46%), Gaps = 17/245 (6%)
Query: 158 NRKNGNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPR 216
++K+ N E N + TGD+ + +G + + GR+D+ IK G +I L IE+ + +
Sbjct: 3677 DKKSQNTEAN--RLYKTGDLARWLPDGNIEFVGRIDNQIKLRGFRIELGEIEALLNGHSQ 3734
Query: 217 VRSCSCVWLQT-----PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTN 271
++ + + L+ + S E+LS++EL +F K KL E P + +D+LP
Sbjct: 3735 IQQAVVIAREDIPGNKRLVAYIVASDESLSTKELREFTKQKLPEYMIPSAFVTLDSLPLM 3794
Query: 272 AHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTS 330
+GK ++ L S + V K+ + + + + L E + +FF +GG S
Sbjct: 3795 PNGKIDRKALPTPDGISPEQEYVAP-KTEIEQHIAQIWQDVLQIEKVGIYDNFFEMGGNS 3853
Query: 331 FLAVTICNKLSLTFP------EVGKH-ILPHLLSHNKSIGDVLKTITQDTNCLENKFKKS 383
L V + +KL F E+ K+ + +L + KS K +T+ N + K K+
Sbjct: 3854 LLLVKVSSKLQELFKMELQVVELLKYPNISYLSQYIKSETPKTKNLTEARNVRDYKLKEG 3913
Query: 384 IKRNR 388
K R
Sbjct: 3914 KKNMR 3918
>UniRef50_Q5W263 Cluster: Putative L-prolyl-AMP ligase; n=2;
Serratia|Rep: Putative L-prolyl-AMP ligase - Serratia sp
Length = 491
Score = 64.1 bits (149), Expect = 1e-08
Identities = 67/269 (24%), Positives = 123/269 (45%), Gaps = 19/269 (7%)
Query: 31 NSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRI 90
++V+ W + PS + N L +L+ + GEP + + L R+
Sbjct: 224 HAVSVWYSVPSILAMLEKSTLLNPTL--GQSLRQVIFAGEPYPVTALKRLLPCLPQPCRV 281
Query: 91 FTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLS--ETELFVQPHEKNNTMGKIILA 148
YG TE + + A +D ++ K+VP+G L +L + +++ ++ L+
Sbjct: 282 SNWYGPTETNVCVAYA-IDRARLAML-KQVPIGLPLEGLTAQLEDENGDRHPLTAQLRLS 339
Query: 149 SK---TRKCILLNRKNGNKEENSI----KFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHK 201
+ + C+ N + + TGD E+ + +RGR+DD +K G++
Sbjct: 340 GELLISGPCVTPGYSNVVVPRQAALHPHQCHATGDWVEMTPEGLVFRGRIDDMVKINGYR 399
Query: 202 INLHSIESTVMQCPRV-RSCSCVWL----QTPLLLI-VYFSAETLSSQELLDFLKCKLDE 255
+ L IES + Q P + R+ CV L QT +++I + A EL FL+ KL
Sbjct: 400 VELGEIESVLHQHPAIDRAALCVELGDLRQTLIMVISLQTGAVPPGLLELKQFLQQKLPS 459
Query: 256 KYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
P+K++ ++LP NA+GK ++ L +
Sbjct: 460 YMIPNKLVITESLPVNANGKVDRKQLAGV 488
>UniRef50_Q1RS73 Cluster: NRPS/PKS protein; n=5; Bacteria|Rep:
NRPS/PKS protein - Bacillus amyloliquefaciens
Length = 4982
Score = 64.1 bits (149), Expect = 1e-08
Identities = 71/301 (23%), Positives = 139/301 (46%), Gaps = 32/301 (10%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
+K+L GGE L+ + LK+ + + K+ + ++G TE + W++V ++T + +
Sbjct: 1401 VKILC-GGEALS--EQLKQ-QFLDTKSEAWNMFGPTETTIWSAV-----QRITENESALT 1451
Query: 122 LGNCLSETELFVQPHEKNNTM----GKIILASKTRKCILLNRKN-------GNKEENSIK 170
+G ++ T +++ N + G++ +A N+ ++ E K
Sbjct: 1452 IGRPIANTRVYIMDSGLNPVLEGVPGELCIAGDGLARGYFNKPELTDKAFVSHRLELGSK 1511
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV---WLQ 226
TGD+ + G + Y GR+D +K G++I IES + P V+ V
Sbjct: 1512 LYKTGDMARFLPGGRIEYMGRMDTQVKIRGYRIEPGDIESRLNAHPAVQESVVVVNNHSG 1571
Query: 227 TPLLLIVYF--SAETL-SSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV- 282
L Y + E L S++EL +K L P +R++ LP +GK +++L
Sbjct: 1572 NEKLCAFYIRKNGEPLPSAKELRKHMKQALPAYMAPASFVRLEELPLTPNGKVDRKLLAA 1631
Query: 283 -NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
++ +K Q + S++ + + A+ L +D++ FF GG S LAVT+ +++
Sbjct: 1632 RDLTEKQPDTQTFSS--SHIQQAVLAIWQDVLKSKDIELDDRFFDAGGDSLLAVTVTDRM 1689
Query: 341 S 341
+
Sbjct: 1690 T 1690
Score = 35.9 bits (79), Expect = 4.0
Identities = 17/49 (34%), Positives = 26/49 (53%)
Query: 171 FIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRS 219
+ +TGD+G +R G + GR D I G H+IES V + P + +
Sbjct: 430 WFETGDLGFLREGRLTITGRTKDAIIINGVNYYSHAIESAVEELPEIET 478
>UniRef50_Q0PH94 Cluster: MassC; n=1; Pseudomonas fluorescens|Rep:
MassC - Pseudomonas fluorescens
Length = 3774
Score = 64.1 bits (149), Expect = 1e-08
Identities = 70/284 (24%), Positives = 123/284 (43%), Gaps = 18/284 (6%)
Query: 69 GEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSE 128
GE L G +++ K + + ++ LYG TE + V D D P+G ++
Sbjct: 1861 GEALPG-SLVRRFKQQLPEVGLYNLYGPTEAA--VDVTAWDCAGALVPDN-TPIGKPIAN 1916
Query: 129 TELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE------NSIKFIDTGDIG 178
T L+V + +G++ +A LNR E + TGD+
Sbjct: 1917 TRLYVLDGQLQPVPLGVVGELFIAGVQVARGYLNRPELTAERFLDDPFTPGRMYRTGDVS 1976
Query: 179 E-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLLLIVYFSA 237
+ +GT+ Y GR DD +K G +I L I++ + + P V+ + + + LI Y++
Sbjct: 1977 RYLPDGTLEYLGRNDDQVKIRGLRIELGEIQARLTEHPAVQEAAVIAREQ--RLIAYYTG 2034
Query: 238 ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENI 297
+ L L L E P + + LP + +GK ++ L + +++ E
Sbjct: 2035 VPSEVESLRAHLLQHLPEFMLPASFVHLQVLPLSPNGKLDRKALPAPGLDALSVRDYEAP 2094
Query: 298 KSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
L AL + LN E + + +FF LGG S LAV++ ++
Sbjct: 2095 VGDTEITLAALWAELLNVERVGRHDNFFELGGHSLLAVSLMGRM 2138
Score = 56.4 bits (130), Expect = 3e-06
Identities = 73/301 (24%), Positives = 126/301 (41%), Gaps = 21/301 (6%)
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
A + L++L GGE + + L R+ YG TE + +A+ E+ +
Sbjct: 2879 ALAGLRILLCGGERADPAAF-RNLLALAPGLRLVHCYGPTETTTYATTHEV--RTIAADA 2935
Query: 118 KEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---ENSIK 170
VP+G +S T+++V + + G+I + LNR E +N
Sbjct: 2936 DSVPVGRPISNTQIYVLDAQLHLLPLGVSGEICIGGDGVAQGYLNRPELTAEKFVQNPFN 2995
Query: 171 ----FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
TGD+G +G + GR DD +K G +I L IE+ + +R +
Sbjct: 2996 PGALLYRTGDLGRWSADGLLECIGRNDDQVKIRGFRIELGEIEARMATFAGIREGVVLAR 3055
Query: 226 QT---PLLLIVYFS--AETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
+ L+ YF+ E + + + +L+ L P + ++ LP A+GK ++
Sbjct: 3056 EDVPGDKRLVAYFTWAGEPVGIESVRAYLQAHLPAYMVPSAFVALEHLPLTANGKVDRKA 3115
Query: 281 LVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNK 339
L ++ E L + L L + L E + + SFF LGG S LA+ + N+
Sbjct: 3116 LPLPTWDASASGTFEAPVDALEQTLAQLWAEVLKLEPVGRHDSFFELGGHSLLAMRLVNR 3175
Query: 340 L 340
L
Sbjct: 3176 L 3176
Score = 51.2 bits (117), Expect = 1e-04
Identities = 61/236 (25%), Positives = 105/236 (44%), Gaps = 30/236 (12%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
TL+ L +GG+ L + + NN YG TE + A+ KV G + +
Sbjct: 818 TLRTLLVGGDRLRQFGRAQRFELINN-------YGPTEATVVATSG-----KVEAG-QPL 864
Query: 121 PLGNCLSETELFV-QPHEKN---NTMGKIILASKTRKCILLNRKNGNKEE------NSIK 170
+G ++ +++V PH++ G++ + K LNR E N+ +
Sbjct: 865 HIGKPIANAKVYVLDPHQRPVPLGVAGELYVGGKGVARGYLNRPELTAERFVRDPFNAGR 924
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL 229
TGD+ + +GT+ Y GR DD +K G +I L IE+ + Q P + V +
Sbjct: 925 MYRTGDLVRWLPDGTLDYLGRNDDQVKIRGVRIELGEIETQLNQLPGILEAVAVVREE-- 982
Query: 230 LLIVYFS----AETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
L+ YF+ + L+ E+ L L + P +++D LP A+GK ++ L
Sbjct: 983 RLVAYFTENPQLDPLTLAEIRAHLVAHLPDYMVPVAFMKLDALPLTANGKLDRKAL 1038
>UniRef50_Q5UXV1 Cluster: Putative cell surface protein OR
serine/threonine protein kinase- related protein; n=1;
Haloarcula marismortui|Rep: Putative cell surface
protein OR serine/threonine protein kinase- related
protein - Haloarcula marismortui (Halobacterium
marismortui)
Length = 347
Score = 64.1 bits (149), Expect = 1e-08
Identities = 56/259 (21%), Positives = 111/259 (42%), Gaps = 18/259 (6%)
Query: 490 VGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYI----ASYDGNIRCIDILTS 545
+G YDG + LE W+ ++G I + TY G LY+ A+ G++ ++ T
Sbjct: 79 IGAYDGALSALDLETGRRRWRTDLGDAIGASPTYYNGSLYVAVEHAAPSGSVVAVNAATG 138
Query: 546 TIK-ETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPV 604
++ +D S + ++ +LFG+ G C +W+ G + A
Sbjct: 139 DVQWRDSRPTDHPHSTVALDREHGRLLFGSNDGYCYAWSFPGLEQVWRYDTGGDVKAPIA 198
Query: 605 LYDNDKYV-IFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCH 663
+ D V +AE + V G + WT+ A ++ +C ++ +Y G H
Sbjct: 199 VADGTAIVPSWAET---VTAVDVTDGSERWTFE-ADADV---MCAPAVH--DGTVYVGSH 249
Query: 664 DNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQ 723
D+ VY++N+ + + W+ + + D +L S +G+L+ + + G V
Sbjct: 250 DDRVYAINLASGEEL--WRYDTGGWIIGSVVATRDH-VLVGSYNGRLYALERDSGAVAWT 306
Query: 724 YQLPGETFSSPIICDDHVF 742
+ G S+P++ D ++
Sbjct: 307 VENRGHVTSAPLVTADGIY 325
Score = 49.2 bits (112), Expect = 4e-04
Identities = 43/228 (18%), Positives = 88/228 (38%), Gaps = 8/228 (3%)
Query: 418 QWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILC 477
+W D G + ASP Y + V + SG +V +NA TG +Q + +
Sbjct: 97 RWRTDLGDAIGASPTYYNGSLYVAVEHAAPSGSVVAVNAATGDVQWRDSRPTDHPHSTVA 156
Query: 478 VHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNI 537
+ E + G+ DG + +W+ + G +K+ G + S+ +
Sbjct: 157 LDREHGRL---LFGSNDGYCYAWSFPGLEQVWRYDTGGDVKAPIAVADGTAIVPSWAETV 213
Query: 538 RCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKG 597
+D+ + + T + A V + + G+ +++ + +W+ G
Sbjct: 214 TAVDVTDGSERWTFEADADVMCAPAV--HDGTVYVGSHDDRVYAINLASGEELWRYDTGG 271
Query: 598 PIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSS 645
I V+ D +V+ NG ++ + G WT +G++ S+
Sbjct: 272 WIIG-SVVATRD-HVLVGSYNGRLYALERDSGAVAWTVEN-RGHVTSA 316
Score = 43.6 bits (98), Expect = 0.020
Identities = 49/236 (20%), Positives = 93/236 (39%), Gaps = 18/236 (7%)
Query: 528 LYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKNEFIL---FGTLSGVCACLHV 584
+YI +YDG + +D+ T + + D AI A + SG ++
Sbjct: 77 VYIGAYDGALSALDLETGRRRWRTDLGD-AIGASPTYYNGSLYVAVEHAAPSGSVVAVNA 135
Query: 585 NTKTIIWQGSLKGPIFACPVLYDNDK-YVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIF 643
T + W+ S V D + ++F +G + + ++W Y+ G++
Sbjct: 136 ATGDVQWRDSRPTDHPHSTVALDREHGRLLFGSNDGYCYAWSFPGLEQVWRYDTG-GDVK 194
Query: 644 SSLCVKEINKF--KWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLI 701
+ + V + W V +V++T+ S W + V P + +D +
Sbjct: 195 APIAVADGTAIVPSWA-------ETVTAVDVTD--GSERWTFEADADVMCAPAV-HDGTV 244
Query: 702 LAASTDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKIDT 757
S D +++ I+ G +Y G S + DHV +G N LY+L+ D+
Sbjct: 245 YVGSHDDRVYAINLASGEELWRYDTGGWIIGSVVATRDHVLVGSYNGRLYALERDS 300
>UniRef50_Q81DB7 Cluster: Peptide synthetase; n=4; Bacillus cereus
group|Rep: Peptide synthetase - Bacillus cereus (strain
ATCC 14579 / DSM 31)
Length = 2156
Score = 63.3 bits (147), Expect = 2e-08
Identities = 78/358 (21%), Positives = 159/358 (44%), Gaps = 30/358 (8%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTL 62
E+ + T G +++ + + + + VT T PS + E ++ K + S++
Sbjct: 1724 ELFVPLTMGGKVIVTENALHL--EKLSTKGVTLVNTVPSV----AKELVRVKTI--PSSV 1775
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
KV+ L GEPL ++++L ++ +++ LYG +E + +++ EL+ + + P+
Sbjct: 1776 KVMNLAGEPLP-YSLVQDLYERSTIEKVYNLYGPSEDTTYSTYMELEKGVMY---RVPPI 1831
Query: 123 GNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKN-------GNKEENSIKF 171
G + TE++V E+ +G++ + LNR + + + +
Sbjct: 1832 GKPIFNTEVYVLSAEQKMVPIGVVGELYIGGSGLARGYLNRPDLTQNLFISHPFKEGERV 1891
Query: 172 IDTGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT--- 227
TGD + + +G + Y GR+D +K G +I L IE+ + + V + +
Sbjct: 1892 YRTGDLVRYLPDGNLEYVGRIDHQVKIRGFRIELGEIEAALQRHILVNEAIVMVREDYPG 1951
Query: 228 PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK 287
LI Y + +Q+ D+LK +L P + ++ P +GK ++ L +K
Sbjct: 1952 DPRLIAYVVGDG-DAQKWRDYLKDQLPNYMIPSYFVGLNAFPLTPNGKIDRKAL-PAPEK 2009
Query: 288 SNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
I ++ K + ++ ++ L E++ SFF +GG S LA + L F
Sbjct: 2010 QEIASCYIAPRTSTEKTIVSIWHEVLGMENIGIQDSFFEIGGHSLLATQAVSNLKEAF 2067
Score = 59.7 bits (138), Expect = 3e-07
Identities = 77/336 (22%), Positives = 154/336 (45%), Gaps = 33/336 (9%)
Query: 31 NSVTFWQTTPSK---FFQHSNENIKNKILCARSTLKVLALGGEPLNG--IKILKELKHKN 85
+ VT Q PS F H N +I+ + C S+++ + GGE L+ ++ ++ +
Sbjct: 694 HQVTIVQFVPSMLSVFLDHFN-HIELNMNC--SSVRHVFSGGEELSSGLVRRFQQKWDYS 750
Query: 86 NKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFV----QPHEKNNT 141
+ ++ YG TE + + + ++ N+ + V +G + T+L+V Q +
Sbjct: 751 GQVKLTNFYGPTEATIYVNAFDIQPNQ-----EFVSIGQPIQNTQLYVLDQNQRLQSIGI 805
Query: 142 MGKIILASKTRKCILLNRKNGNKEE---NSIKFID----TGD-IGEIRNGTVFYRGRVDD 193
G++ + LNR N E+ + +F + TGD + + +G + + GR+D
Sbjct: 806 EGELYIGGAGLARGYLNRPNLTAEKFVSHPYRFGERLYRTGDSVRYLTDGNLEFIGRMDH 865
Query: 194 TIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT---PLLLIVYFSAETLSSQELLDFLK 250
+K G +I L IE+T+ +C ++ + + L+ Y ++ ++QE ++L+
Sbjct: 866 QVKMRGFRIELGEIEATLEKCSFIKEAVVLVREDRPGDQRLVAYVISDG-NTQEWREYLQ 924
Query: 251 CKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALV- 309
+L P I ++ P +GK ++ L +++++ + +EL A V
Sbjct: 925 KQLPTHMIPAHFIELEHFPLTPNGKIDRKALP--APDEQVIEDLNVLPRTPSEELIASVW 982
Query: 310 NKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
+ L E++ SFF GG S LA I ++L F
Sbjct: 983 GQVLGIENISIQDSFFERGGHSLLATQIVSRLQELF 1018
>UniRef50_Q5WUR2 Cluster: Putative uncharacterized protein; n=2;
Legionella pneumophila|Rep: Putative uncharacterized
protein - Legionella pneumophila (strain Lens)
Length = 2316
Score = 63.3 bits (147), Expect = 2e-08
Identities = 70/306 (22%), Positives = 132/306 (43%), Gaps = 29/306 (9%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKT----RIFTLYGVTEMSCWASVAELDLNKVTTGD 117
L ++ GGE +N +LK K ++ +YG TE + ++S + K T +
Sbjct: 268 LHTISFGGEQVNA-HLLKNFIDYRKKADIPIKLVNVYGPTEATVFSSCNIIHSEKEYTDE 326
Query: 118 KEVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSIK------- 170
+ +G + T+ ++ ++ T + S + + +E +K
Sbjct: 327 QLASIGFKTANTKTYILDDNRHRTAEGELWVSGVHLALHYHNSPEQTKEKFVKNPFSRND 386
Query: 171 ----FIDTGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
TGD + ++ +G + Y GRVDD +K G +I+L +E +M + S + V +
Sbjct: 387 LYSRMYRTGDKVRQLPSGELLYLGRVDDQVKIGGFRIHLTEVEQELMNHEAI-SLAAVTV 445
Query: 226 QTP------LLLIVYFSAETL--SSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ L + F ++ + + E+ FL KL P K + V+ LP A GK
Sbjct: 446 EIGGGAHKFLTAYLVFKSKDIIVDADEIRSFLSQKLPPYMLPAKYVMVEKLPLTAVGKID 505
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKE-LKALVNKDLNYEDLQS-KSFFSLGGTSFLAVT 335
K L I +++ +++ S +E +K + LN ++S K+ F LG S L
Sbjct: 506 KAKLDKI-AHTDLSFHIDTSSSNPIEETIKNIWRHLLNRSSIESHKNLFELGANSLLITE 564
Query: 336 ICNKLS 341
C +++
Sbjct: 565 ACAQIN 570
>UniRef50_Q1D6B8 Cluster: Non-ribosomal peptide synthetase; n=5;
Bacteria|Rep: Non-ribosomal peptide synthetase -
Myxococcus xanthus (strain DK 1622)
Length = 4567
Score = 63.3 bits (147), Expect = 2e-08
Identities = 57/175 (32%), Positives = 80/175 (45%), Gaps = 8/175 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR-SCSCVWLQTPLL- 230
TGD + G + + GR+D +K G +I L IES + Q P VR + V TP L
Sbjct: 4084 TGDRARWLPQGELEFLGRIDFQVKLRGFRIELGEIESALRQHPAVRDTVVLVREDTPGLQ 4143
Query: 231 -LIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L+ Y AE T+ S FLK +L E P + ++ LP N GK + L +
Sbjct: 4144 RLVAYVVAEPAATVDSGTFRPFLKERLPEHMMPSAFVTLEALPLNTSGKVDRRALPLPEE 4203
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKS-FFSLGGTSFLAVTICNKL 340
S + + EL L + L + +KS FF LGG S LAV + + L
Sbjct: 4204 TSPRHEVYVPPRDAYELELARLFEELLGVSPISAKSDFFELGGHSLLAVRLLSML 4258
Score = 49.2 bits (112), Expect = 4e-04
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 12/181 (6%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR-SCSCVWLQTPLL- 230
TGD + G + + GR+D +K G +I L IES + Q P VR + V TP L
Sbjct: 1956 TGDRARWLPQGELEFLGRIDFQVKVRGFRIELGEIESALRQHPAVRDTVVLVREDTPGLQ 2015
Query: 231 -LIVYFSAET-----LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
L+ Y AE + S FLK +L E P + ++ LP +GK ++ L
Sbjct: 2016 RLVAYVVAEAEATTVVDSGTFRPFLKERLPEHMVPSAFVTLEALPLTPNGKLDRKALPAP 2075
Query: 285 YKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKS-FFSLGGTSFLAVTICNKLSLT 343
+ + + + + A L+ E + ++ FF+LGG S LA + +L
Sbjct: 2076 EAPRSAA--TRPLSTETERRVAAHWATLLHVETVNAEDDFFALGGHSLLATQLVTRLRQD 2133
Query: 344 F 344
F
Sbjct: 2134 F 2134
Score = 41.9 bits (94), Expect = 0.062
Identities = 48/182 (26%), Positives = 80/182 (43%), Gaps = 15/182 (8%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT---PL 229
TGD R +G++ + GR D +K G +I L IES + Q P V+ + +
Sbjct: 888 TGDRVRWRADGSLEFLGRSDFQVKVRGFRIELGEIESVLQQAPGVQEAVVLAREDAPGDK 947
Query: 230 LLIVYF--SAETLSSQE-------LLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
L+ YF +A S ++ + FLK +L E P + ++ LP + +GK ++
Sbjct: 948 RLVAYFVPTAAARSEEQAANAVGGIRTFLKARLPEYMLPAVFMPLEVLPLSPNGKVDRKA 1007
Query: 281 LVNIYKKSNILQN-VENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICN 338
L Y N E ++ + L + + L + SFF LGG S ++ +
Sbjct: 1008 LPAPYADLNRTGTPFEAPRNASEQTLADIWAEVLGLRQVGIDDSFFELGGDSIRSIQVIA 1067
Query: 339 KL 340
KL
Sbjct: 1068 KL 1069
Score = 41.5 bits (93), Expect = 0.081
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 8/116 (6%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ-TP--L 229
TGD R +G++ + GR D +K G +I L IES + Q P V+ + + +P
Sbjct: 3019 TGDRVRWRADGSLEFLGRSDFQVKVRGFRIELGEIESVLQQAPGVQEAVVLAREDSPGDK 3078
Query: 230 LLIVYF----SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
L+ Y E++ ++ L D + KL E P I +++LP +A+GK ++ L
Sbjct: 3079 RLVAYVVGEDGVESVDARALRDHVLRKLPEYLVPAIFIPMESLPLSANGKVDRKAL 3134
>UniRef50_A7BKL9 Cluster: Non-ribosomal peptide synthetase; n=2;
Beggiatoa sp. SS|Rep: Non-ribosomal peptide synthetase -
Beggiatoa sp. SS
Length = 627
Score = 63.3 bits (147), Expect = 2e-08
Identities = 74/305 (24%), Positives = 133/305 (43%), Gaps = 25/305 (8%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ L +G EP+ K L+ + + + RI YG TE + A++ + + +++ P
Sbjct: 274 LQRLLVGVEPIVQ-KTLQLFRQLSPQLRIINGYGPTEATVCATL--FNFEQAEEPERQTP 330
Query: 122 LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE--------NSI 169
+G ++ +++V E N G++ +A LNR E+
Sbjct: 331 IGKPVANYQVYVLDTENALLPINIPGEVCIAGAGVARGYLNRPELTAEKFIEVVLFGKRE 390
Query: 170 KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP 228
+ TGD+ + +G + Y GR+D +K G +I L IE+ + Q P V+ V
Sbjct: 391 RIYKTGDLARWLPDGNLEYLGRIDHQVKLRGFRIELGEIEAVLCQHPEVKEAVVVLYDAD 450
Query: 229 --LLLIVYFSAETLSSQ-----ELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
L+ Y S + +Q EL + LK +L + P ++ +D LP ++GK ++ L
Sbjct: 451 DNKRLVAYVSVDKELTQADLASELKNSLKQQLPDYMIPADLMVLDALPLTSNGKIDRKAL 510
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
S E +S +++ + L E L SFF +GG S L + + + L
Sbjct: 511 -PAPDTSLSAARYEPPRSQAEQKIAVAWEQVLKRERLSIHDSFFEVGGHSLLVIQMHSLL 569
Query: 341 SLTFP 345
+P
Sbjct: 570 CADYP 574
>UniRef50_A6EWZ1 Cluster: Peptide synthetase; n=1; Marinobacter
algicola DG893|Rep: Peptide synthetase - Marinobacter
algicola DG893
Length = 1501
Score = 63.3 bits (147), Expect = 2e-08
Identities = 81/361 (22%), Positives = 161/361 (44%), Gaps = 35/361 (9%)
Query: 2 VEILLACTNGASLLIAPDLT----EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC 57
+E+LL T GA+ +IA + E L D+ ++ Q TP+ + + + + +
Sbjct: 664 LELLLPLTQGATTVIADKDSVKDGEKLRQLILDHQISIMQATPATWRILLDTDWRQDGVR 723
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
R GGEPL ++++L ++ ++ +YG TE + W++ L L D
Sbjct: 724 MRGLC-----GGEPLPQ-DLVRDLLGCLDE--LWNMYGPTETTVWSTCHRLRLT-----D 770
Query: 118 KEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE-----NS 168
+ + +G + T++ + E N + G++ + NR E+
Sbjct: 771 RLISIGQPIGNTQVHILDRECNPLPLSCPGELYIGGLGLATGYHNRPELTAEKYVDHPTH 830
Query: 169 IKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRS-CSCVWLQ 226
+ TGD+ + +G + + GR+DD +K G++I L IES ++ CP V+S C+ VW
Sbjct: 831 GRLYATGDLAKWDPDGNLQHLGRMDDQVKVRGYRIELGDIESALVTCPDVKSACAYVWEL 890
Query: 227 TP-----LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
+P + +V S + + L+ L P +I ++ +P + GK + L
Sbjct: 891 SPGDARIVGCVVSESGNEPNVVNIRKELRKVLPAYMIPQYIIAIEAVPLSPSGKMDRRRL 950
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYED--LQSKSFFSLGGTSFLAVTICNK 339
+ + + + + + + + + LN + ++ +FFSLGG S LA+ +
Sbjct: 951 PKPELRESSILKASALANQTEEMIADVWSDVLNSKSRIVREDNFFSLGGHSLLALQAIRR 1010
Query: 340 L 340
+
Sbjct: 1011 I 1011
>UniRef50_Q8YTR9 Cluster: Peptide synthetase; n=2; Nostocaceae|Rep:
Peptide synthetase - Anabaena sp. (strain PCC 7120)
Length = 2617
Score = 62.9 bits (146), Expect = 3e-08
Identities = 85/371 (22%), Positives = 163/371 (43%), Gaps = 46/371 (12%)
Query: 2 VEILLACTNGASL-LIAPDLT---EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC 57
+EI L GA L L+ ++T E L + +TF Q TP+ + + K
Sbjct: 687 LEIFLPLIVGACLVLVEREVTLDGERLAQAIAQHQITFMQATPATWRLLLASGWEGK--- 743
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
LK+L GGE L+ + ++L + ++ LYG TE + W++ +L + D
Sbjct: 744 --QDLKILC-GGEALDNT-LAQQLLSCTQE--VWNLYGPTETTIWSAAQKLSI------D 791
Query: 118 KEVPLGNCLSETELFVQPHEKN----NTMGKIILASK------------TRKCILLNRKN 161
+ V +G+ ++ T+ +V G++ + T + L +
Sbjct: 792 EPVTIGHPIANTQFYVLDEHLQPVPIGVPGELYIGGAGVAKGYWQRPDLTAERFLNQQST 851
Query: 162 GNKEENSIKFI-DTGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV-R 218
N +++++ + TGD + + +G + Y GR+D +K G +I L IE+ + Q P++ +
Sbjct: 852 VNSQQSTVNTLYKTGDRVRYLPDGKLEYLGRLDYQVKIRGFRIELGEIEAVLAQHPQISQ 911
Query: 219 SCSCVWLQTP----LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
+ V P L+ + +++ + S +L FL KL + P + + LP +G
Sbjct: 912 AVVSVQEDEPGEQRLVAYIVPNSQDVGSNDLQQFLANKLPKYMIPGVFVTLTALPLTPNG 971
Query: 275 KTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLA 333
K ++ L +S + + + + A+V L E + +FF LGG S LA
Sbjct: 972 KVDRKALPTPNTQSQVNETPRTPTEEVLASIWAMV---LGVESVGIEDNFFDLGGHSLLA 1028
Query: 334 VTICNKLSLTF 344
+ +++ F
Sbjct: 1029 TRLISQVRQVF 1039
Score = 62.1 bits (144), Expect = 5e-08
Identities = 76/337 (22%), Positives = 154/337 (45%), Gaps = 35/337 (10%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
+T++ + L GEPL ++ EL ++ R++ LYG +E + +++ A + N ++
Sbjct: 1783 ATVQTVNLAGEPLPK-SLVDELYQQSTIERVYNLYGPSEDTTYSTHALIPRNS-----QQ 1836
Query: 120 VP-LGNCLSETELFVQPHEKN----NTMGKIILAS--------KTRKCI---LLNRKNGN 163
P +G ++ T++++ G+I L+ K K + + N
Sbjct: 1837 APTIGQPIANTQVYILDQNLQPVPVGIPGEIYLSGAGLARGYWKRPKLTDERFIKQSTVN 1896
Query: 164 KEENSIKFI-DTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV-RSC 220
+++++ + TGD + +G + Y GR D +K G +I L IE+ + Q P + ++
Sbjct: 1897 SQQSTVNTLYKTGDRARYLPDGNIEYLGRFDHQVKLRGFRIELGEIEALLHQHPELTQAV 1956
Query: 221 SCVWLQTP--LLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ V TP L+ Y ++ + + EL FL KL P + ++TLP A+GK
Sbjct: 1957 AIVRNDTPEHSRLVAYVVPKSHIEAAELRQFLAAKLPAYMLPTAFVILETLPLTANGKVD 2016
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTI 336
+ + I S + ++ + ++L + + L E + +FF LGG S LA+
Sbjct: 2017 R-FALPIPDLSPVTTTTAP-RTPIEQQLINIWTQVLGVESISIHDNFFRLGGDSILAIQA 2074
Query: 337 CNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQDT 373
K + + G + P + +++ ++ + DT
Sbjct: 2075 VAKAN----QQGLALRPRQMFQYQTVAELAAIVDTDT 2107
>UniRef50_Q8CQA8 Cluster: Surfactin synthetase; n=14;
Staphylococcus|Rep: Surfactin synthetase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 2400
Score = 62.9 bits (146), Expect = 3e-08
Identities = 80/340 (23%), Positives = 145/340 (42%), Gaps = 29/340 (8%)
Query: 15 LIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNG 74
L+ P L + E+ N T W T+ S F Q ++E I+ A +L L +GGE LN
Sbjct: 650 LLNPQLLDQAITENKVN--TMWLTS-SLFNQIASERIE-----ALESLTYLLIGGEVLNA 701
Query: 75 IKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQ 134
K + L + +I YG TE + + + + + +P+G +S T ++V
Sbjct: 702 -KWVHLLNSRECHPQIINGYGPTENTTFTTTFAIPQEMPS----RIPIGLPISGTTVYVM 756
Query: 135 PHEKN---NTMGKIILASKTRKCILLNRKNGNKEE------NSIKFIDTGDIGEIR-NGT 184
+ G++ + LN+ E N+ +GD+ ++ +G
Sbjct: 757 QGNRICGVGVPGELCIGGAGLAKGYLNQPKLTAERFIQSPFNNEMLYRSGDLVRLQEDGY 816
Query: 185 VFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--LLIVYFSAETLSS 242
+ Y R+D +K G +I L IE + + + + ++ Y+ A L S
Sbjct: 817 IDYISRIDKQVKIRGFRIELSEIEKALEAIRDINKAVVIVREQDQDKQIVAYYEASQLKS 876
Query: 243 Q-ELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYL 301
+L D L L E P ++VD +P +GK L I K+N +N ++ +
Sbjct: 877 TGQLKDILSETLPEYMVPVHFMKVDRIPITMNGKLDVRSLPEINLKNN--RNYVEPRNDI 934
Query: 302 FKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKL 340
+ + + + L+ + + K +FF LGG S A + N++
Sbjct: 935 ERTVCRIFEEILHVDQVGVKDNFFELGGHSLRATLVVNRI 974
Score = 45.2 bits (102), Expect = 0.007
Identities = 49/236 (20%), Positives = 100/236 (42%), Gaps = 20/236 (8%)
Query: 120 VPLGNCLSETELFVQPHEKN---NTMGKIILASKTRKCILLNRKNGNKEE---NSI---K 170
+P+G L+ ++F+ K G++ +A ++ LNR + E+ N +
Sbjct: 1759 IPIGKPLANVDIFIMSGGKLCGVGIPGELCIAGESLTSGYLNRPELSAEKFINNPFGPGQ 1818
Query: 171 FIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL 229
+GD+ + +G + + GR+D +K G++I L IE+ + V + +
Sbjct: 1819 LYRSGDLARLMPDGQIEFLGRIDKQVKVHGYRIELGEIENIINSVDTVTDSVVILAKQGE 1878
Query: 230 --LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV--NIY 285
+L Y+ + L L + P + + +P + K + L N++
Sbjct: 1879 REVLHAYYVGSQEDENHISQHLNQYLPKYMIPKTLTAISEIPLTGNDKVDESRLPVPNVH 1938
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
K + NI+ +E+ +V+ L+ + FF +GGTS A+ + +KL
Sbjct: 1939 KNKFVAPR-NNIE----REIAQIVSGVLDVSSMSIDDDFFEMGGTSLDAMVVVSKL 1989
>UniRef50_Q5MP00 Cluster: OnnI; n=1; symbiont bacterium of Theonella
swinhoei|Rep: OnnI - symbiont bacterium of Theonella
swinhoei
Length = 5052
Score = 62.9 bits (146), Expect = 3e-08
Identities = 70/299 (23%), Positives = 130/299 (43%), Gaps = 32/299 (10%)
Query: 90 IFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKI 145
++ LYG TE + W++V + N+ + +G + T +++ H + G++
Sbjct: 1593 VWNLYGPTETTIWSAVQRIRENEA------IVIGKPIQNTGIYILDHNRALVPIGVPGEL 1646
Query: 146 ILASKTRKCILLNRKNGNKEE-------NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKR 197
+ L++ E+ K TGD+ + NGT+ Y GR+D +K
Sbjct: 1647 CIDGDGLARGYLHKPELTAEKFMDHPFHRGKKIYHTGDLARWLPNGTIEYLGRLDLQVKI 1706
Query: 198 FGHKINLHSIESTVMQCPRVRSCSCVW------LQTPLLLIVYF----SAETLSSQELLD 247
G +I L IE + Q P +R V ++ L+ YF E++ ++ L
Sbjct: 1707 RGFRIELGEIEFQLKQLPGIRDAVVVAKDMAKDMEGLHQLVAYFIPGGGPESVDTEVLRA 1766
Query: 248 FLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKA 307
LK KL + P I ++ +P +GK ++ L+ N Q +S + + L
Sbjct: 1767 GLKQKLADYMVPAFFIPLEEIPLTPNGKVDRKTLMERDILVNRSQEHTQPQSAIEESLLE 1826
Query: 308 LVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDV 365
+ L +++ + FF+LGG S LAV + +++ T +G P L + SI ++
Sbjct: 1827 IWQDILKIDNISPTDGFFALGGNSVLAVRLAERIAQT---LGMPFNPTALFKHASIREI 1882
>UniRef50_Q0LKI6 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1569
Score = 62.9 bits (146), Expect = 3e-08
Identities = 79/339 (23%), Positives = 141/339 (41%), Gaps = 28/339 (8%)
Query: 30 DNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKEL--KHKNNK 87
D VT TPS F Q + ++ L +R L+ + GGE LN + L+ +H + +
Sbjct: 730 DEGVTVLNQTPSAFRQLIISDAEHD-LPSRLALRYVIFGGEALN-VGALQPWFERHGDLR 787
Query: 88 TRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHE----KNNTMG 143
++ +YG+TE + + L ++ V P+G + + +L+V G
Sbjct: 788 PQLVNMYGITETTVHVTYRPLSMHDVENPQSS-PIGTAIPDLDLYVLDDHCLPVPLGITG 846
Query: 144 KIILASKTRKCILLNRKNGNKEE-------NSIKFIDTGD-IGEIRNGTVFYRGRVDDTI 195
++ + NR E + + TGD + + N + Y GR D+ +
Sbjct: 847 ELYVGGAGLARGYWNRPELTNERFIKHPFAETGRLYKTGDLVRRLANNEIEYLGRRDNQV 906
Query: 196 KRFGHKINLHSIESTVMQCPRVRSCSCVWLQT----PLLLIVYFSA---ETLSSQELLDF 248
K G +I L I++T+M P + + V + T L+ Y + +L F
Sbjct: 907 KIRGFRIELGEIQATLMSHPAITD-AIVAVNTISADDQRLVAYLVTQPNQVPRFSQLRTF 965
Query: 249 LKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNI--LQNVENIKSYLFKELK 306
LK +L E P I ++ +P A+GK L + + + Q + S + L
Sbjct: 966 LKQRLPEYMVPTSFIMLERIPLTANGKIDYRALPSQQQTKQLERSQPIAAPTSVTEQSLI 1025
Query: 307 ALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
A+ + L + +FF LGG S LA + +++ F
Sbjct: 1026 AIWSNLLGVTQVGIQDNFFDLGGHSLLATQVISRVREVF 1064
>UniRef50_A5Z6T7 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 494
Score = 62.9 bits (146), Expect = 3e-08
Identities = 65/236 (27%), Positives = 96/236 (40%), Gaps = 24/236 (10%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ + LG PL+ K + LK T++F +YG TE C S L+ +K GDK+
Sbjct: 264 LRYIQLGSAPLSE-KAKETLKEMFPNTKLFNIYGATESGCTVS---LEFSKY--GDKKGS 317
Query: 122 LGNCLSETELFVQPHEKN------NTMGKIILASKTRKCILLNRKNGNKE----ENSIKF 171
+G E+ +N G + L KE E ++
Sbjct: 318 IGKPNVNAEIIFVDDNRNIVKASAQNPGNLAFKGAMNMPGYLKEPEITKEVMDDEGTLYT 377
Query: 172 IDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL------ 225
D G +GE +G V+ GR D I G KI IE V Q ++ C+C+ +
Sbjct: 378 NDLGYMGE--DGFVYLLGRKGDVINMGGIKIAPSEIEEVVAQNEMIKECACIPIPDEITG 435
Query: 226 QTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
+ P L IV + L F+ KL+ P V +D LP +GK K +L
Sbjct: 436 EAPKLFIVINEGFEYDEKSLHRFMLEKLEAIRVPKVVQVIDALPRTFNGKVIKRML 491
>UniRef50_O68007 Cluster: Bacitracin synthetase 2 (BA2) [Includes:
ATP-dependent lysine adenylase (LysA) (Lysine activase);
ATP-dependent D-ornithine adenylase (D-OrnA) (D-ornithine
activase); Ornithine racemase (EC 5.1.1.12)]; n=4;
Bacillus|Rep: Bacitracin synthetase 2 (BA2) [Includes:
ATP-dependent lysine adenylase (LysA) (Lysine activase);
ATP-dependent D-ornithine adenylase (D-OrnA) (D-ornithine
activase); Ornithine racemase (EC 5.1.1.12)] - Bacillus
licheniformis
Length = 2607
Score = 62.9 bits (146), Expect = 3e-08
Identities = 80/354 (22%), Positives = 149/354 (42%), Gaps = 26/354 (7%)
Query: 10 NGASLLIAPDLTEV----LFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVL 65
NG ++ I PD ++ L+ N + ++TPS +K+ S++K+L
Sbjct: 1756 NGGTMYIVPDDVKLEMNLLYDMINKYGIHMLESTPSLIIPLMKYIDHHKL--DFSSMKLL 1813
Query: 66 ALGGEPLNGIKILKELKHK-NNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGN 124
+G + IK K L + + RI YGVTE S + E L+++ P+G
Sbjct: 1814 IMGSDTCT-IKDYKWLVERFGQRMRIINSYGVTEASVDSGYYEEALDRIPE-IANTPIGK 1871
Query: 125 CLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE---NSI----KFID 173
L T ++ N G++ + + LN+ KE N
Sbjct: 1872 PLDNTAFYILDPSLNPQPVGVYGELYIGGEGIARGYLNKPELTKERFVPNRFAAGGNMYK 1931
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--- 229
TGD+ + +G V + GR+D +K G +I IE+ +++ + + +
Sbjct: 1932 TGDLARWLPDGNVEFLGRIDHQVKIRGFRIETGEIETKLLENQNISEAVVIDREDKKGHK 1991
Query: 230 LLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L Y A ++ EL ++L L + P I+++ +P +GK ++ L
Sbjct: 1992 YLCAYIVARAKTNTNELREYLSDHLPDYMLPSYFIQINKMPLTPNGKIDRKALPEPAGDV 2051
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLS 341
E ++ ++L A+ + L+ + + + +FF +GG S A+ I +KLS
Sbjct: 2052 IAASGYEAPRNETEEKLAAVWQEVLDRDKIGINDNFFEIGGDSIKALQIVSKLS 2105
>UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibiotic
biosynthesis; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to proteins involved in antibiotic
biosynthesis - Photorhabdus luminescens subsp. laumondii
Length = 3270
Score = 62.5 bits (145), Expect = 4e-08
Identities = 86/367 (23%), Positives = 162/367 (44%), Gaps = 34/367 (9%)
Query: 1 MVEILLACTNGASLLIAP--DLTEV--LFHEDNDNSVTFWQTTPSKFFQHSNENIKNKIL 56
++E+ L +GA+ ++A D+T+ L +S++ Q TP+ + +
Sbjct: 733 VLELYLPWLSGATCVVAAQQDVTDPARLVALLEQHSISLLQATPTTWNMLLESGWQG--- 789
Query: 57 CARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
RS+LK+++ GGE L + L K + ++ +YG TE + W+++A+LD+ +
Sbjct: 790 --RSSLKMIS-GGEALP-LATATALLSKGSA--LWNMYGPTETTVWSTIAKLDVQLLE-- 841
Query: 117 DKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEEN-SIKF 171
+ V +G L+ T +++ + +G++ + R++ E ++ F
Sbjct: 842 QQLVTIGLPLNNTTIYLLDEQLKPVPFGAVGELYIGGDGLAEGYFKREDLTTERLINLTF 901
Query: 172 ID--------TGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
D TGD+ G++ Y GR D +K GH+I L IE + P++
Sbjct: 902 SDGLTAKVYKTGDLARYTTEGSLVYLGRNDYQVKLRGHRIELGEIEQVINLFPQITRSVV 961
Query: 223 VWL---QTPLLLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
V L QT L Y AE + L L+ KL P +I+++TLP + K +
Sbjct: 962 VALNDQQTQQYLAGYVVAEQQIDIDALRQHLEQKLPAYMLPRAIIQLETLPLTLNNKIDR 1021
Query: 279 EILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTIC 337
+ L ++ L A+ + L+ E + + +FF +GG S +A +
Sbjct: 1022 KALPTPQDSDIAVKASTPPIGETEAALAAIWCEMLDIERIGRDDNFFMVGGHSLIATKVI 1081
Query: 338 NKLSLTF 344
K++ F
Sbjct: 1082 TKINEQF 1088
Score = 60.9 bits (141), Expect = 1e-07
Identities = 47/180 (26%), Positives = 82/180 (45%), Gaps = 12/180 (6%)
Query: 174 TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--- 229
TGD+ +NG + Y GR D +K G +I L IE+ + + + + + T
Sbjct: 3048 TGDLASFHQNGEINYFGRNDHLVKIRGFRIELGDIEAQLSKFDGITGTVVIAIDTEAGDK 3107
Query: 230 LLIVYF-SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL----VNI 284
LI YF +A L E+ +L L + P +R+ P N +GK + L +
Sbjct: 3108 QLIAYFIAANPLDLSEIKTYLSASLPDYMLPSAYVRMAAFPLNTNGKVDRSRLPQPEADN 3167
Query: 285 YKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTF 344
+ K+ + V ++ + K + L+ +D + SFF LGG S LA+ + +++ F
Sbjct: 3168 FVKAKYIAPVTELERSVAKIWQGLLQQD---RVSMADSFFDLGGHSLLAMKLISRIEQAF 3224
Score = 44.0 bits (99), Expect = 0.015
Identities = 69/314 (21%), Positives = 133/314 (42%), Gaps = 30/314 (9%)
Query: 48 NENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAE 107
+E + + + ++ +++GGE + K++ + + R+ YG TE + +A
Sbjct: 1837 HEVVSEETVLVPEHIRQISVGGEQIKPDKVVAWYQRPGHLPRLVNAYGPTEYTVNTCIA- 1895
Query: 108 LDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGN 163
DL GD + +G+ + T +F+ + +G+I +A +N++
Sbjct: 1896 YDLR----GD-TLSIGHPIQNTAIFLLDKNQQLVPFGAVGEICVAGDGVARGYINKEQLT 1950
Query: 164 KE---ENSI-----KFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQC 214
+E +N K TGD+G G + Y GR D +K G +I L IE+ +
Sbjct: 1951 RERFIDNPFVSRYPKLYRTGDLGRYSLAGDIQYYGRDDHQVKIRGFRIELGEIETRLRSL 2010
Query: 215 PRVRSCSCVWLQTPLLLIVYFSAETLSSQ----ELLDFLKCKLDEKYWPDKVIRVDTLPT 270
P +R + + + TL Q E+ L +L P + ++ +P
Sbjct: 2011 PTIRDAVVIAREDEPAHKYLAAYITLDGQQKVAEIRHLLSQQLPSYMVPAAFVVLEEIPL 2070
Query: 271 NAHGKTSKEILVNIYKKSNILQ-NVENIKSYLFKE-LKALVNKDL-NYEDLQS-KSFFSL 326
A+ K ++ L K ++Q +E I +E L A + + L + + +FF L
Sbjct: 2071 TANRKVDRKALP---KPDFVIQGEIEYIAPATEQETLLAEIWRTLFGLAQVSAVANFFEL 2127
Query: 327 GGTSFLAVTICNKL 340
GG S L++ + + L
Sbjct: 2128 GGHSLLSMKMLSHL 2141
>UniRef50_A6FDW3 Cluster: Probable peptide synthetase protein; n=1;
Moritella sp. PE36|Rep: Probable peptide synthetase
protein - Moritella sp. PE36
Length = 609
Score = 62.5 bits (145), Expect = 4e-08
Identities = 73/324 (22%), Positives = 140/324 (43%), Gaps = 24/324 (7%)
Query: 4 ILLACTNGASLLIAPDLT---EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARS 60
+ +A T+G+ L+ DL V+ + ++ + + PS F+ ++E ++++ S
Sbjct: 217 LFIALTSGSRLIFMNDLIFEPAVIAEQIDEEDIDWINCAPSAFYLIADEGQQSQL----S 272
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
+L+ + LGGE +N KI K N + YG TE C V L + +
Sbjct: 273 SLRQVVLGGESINPKKIRTYRKLGLN-CQFINSYGPTE--CTDVVMYHILEDIDYERDYI 329
Query: 121 PLGNCLSETELFV-QPHEKNNTMGKIILASKTRKCILLNRKNGNKEE-----NSIKFIDT 174
PLG + T+ + + H G++IL +N + + IK T
Sbjct: 330 PLGKSIDNTQFELDKSHFSGKNTGELILKGICVGNGYINNSEQTAKSFFVDMDQIKSYRT 389
Query: 175 GDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLLLIV 233
GD+ ++ NG + + R DD IK G++I L +E+ + C + L+ +
Sbjct: 390 GDLVKLESNGCLKFISRKDDQIKLHGYRIELGEVEANLNLCEYINMSVVKLGHEELIAYI 449
Query: 234 YFSAETLSSQELLDFLKCKLD-----EKY-WPDKVIRVDTLPTNAHGKTS-KEILVNIYK 286
+ + + + K KL Y P + I ++ P N +GK K L++ ++
Sbjct: 450 QPISGCDNWDDKIHITKIKLQLAKQLPSYSLPSRYIVLEQFPLNRNGKIDRKSPLLSTHE 509
Query: 287 KSNILQNVENIKSYLFKELKALVN 310
+S+ ++E+ K ++ L+N
Sbjct: 510 QSDQSGSLEHFNKVTPKLIRTLLN 533
>UniRef50_A6BZI6 Cluster: Probable serine/threonine protein kinase
related protein; n=1; Planctomyces maris DSM 8797|Rep:
Probable serine/threonine protein kinase related protein
- Planctomyces maris DSM 8797
Length = 408
Score = 62.5 bits (145), Expect = 4e-08
Identities = 55/233 (23%), Positives = 92/233 (39%), Gaps = 10/233 (4%)
Query: 525 KGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHV 584
KGV Y+ DG ID+ T + IS+ V A + +LFG+ CL
Sbjct: 145 KGV-YLGDEDGIFHAIDLKTGKKLWQFKTDAEIISSANVTADGK-LLFGSYDNSLYCLKE 202
Query: 585 NTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFS 644
N +++W+ G + P + +N F V G C + I I T +
Sbjct: 203 NDGSLVWRFETDGYVNCSPAIVEN-----FTFVTG---CDEQLRVIDIATGKQHSIMPLA 254
Query: 645 SLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAA 704
+ + +Y G + + + SVN + +K Y + D+ ++A
Sbjct: 255 TYLIASPALMGDNLYVGTYASEIISVNWKELRVDWRFKDPKKEFPYHSSAAITDEYVVAG 314
Query: 705 STDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKIDT 757
D ++ + + G + G SSP+I + VFIG +D LY L + T
Sbjct: 315 GRDKQVHCVDRKTGKSVWDFATRGRVDSSPVILGNRVFIGSSDDNLYELDLKT 367
Score = 58.0 bits (134), Expect = 9e-07
Identities = 45/225 (20%), Positives = 97/225 (43%), Gaps = 16/225 (7%)
Query: 491 GTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKET 550
G+YD ++ C + S++W+ + + ++ D +R IDI T
Sbjct: 191 GSYDNSLYCLKENDGSLVWRFETDGYVNCSPAIVENFTFVTGCDEQLRVIDIATGKQHSI 250
Query: 551 VHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYD--- 607
+ ++ I++ ++ N ++ GT + + VN K + K P P
Sbjct: 251 MPLATYLIASPALMGDNLYV--GTYAS--EIISVNWKELRVDWRFKDPKKEFPYHSSAAI 306
Query: 608 NDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNV 667
D+YV+ + ++HC + G +W + +G + SS + +++ G D+N+
Sbjct: 307 TDEYVVAGGRDKQVHCVDRKTGKSVWDF-ATRGRVDSSPVI-----LGNRVFIGSSDDNL 360
Query: 668 YSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAA-STDGKLW 711
Y +++ + WK + + ++P I + LI+ S +G L+
Sbjct: 361 YELDLKTGKNI--WKKNLGDDITASPAIGSGHLIIGTESRNGALY 403
Score = 43.2 bits (97), Expect = 0.027
Identities = 33/166 (19%), Positives = 69/166 (41%), Gaps = 10/166 (6%)
Query: 589 IIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKG----NIFS 644
++WQ + I + + N Y+ A +NG + C ++ G IW Y +
Sbjct: 77 LLWQHTSSDGIASTAAIVGNRVYM--AGLNGYVECLDLKTGKPIWKYRSIENPDPKEFAP 134
Query: 645 SLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAA 704
+ K +Y G D +++++ + W+ + + + S+ + D +L
Sbjct: 135 GFKASPLVTAK-GVYLGDEDGIFHAIDLKTGKKL--WQFKTDAEIISSANVTADGKLLFG 191
Query: 705 STDGKLWVIHSELGTVTAQYQLPGETFSSPIICDDHVFI-GCRNDL 749
S D L+ + G++ +++ G SP I ++ F+ GC L
Sbjct: 192 SYDNSLYCLKENDGSLVWRFETDGYVNCSPAIVENFTFVTGCDEQL 237
>UniRef50_A0ZF82 Cluster: Non-ribosomal peptide synthase; n=2;
Nostocaceae|Rep: Non-ribosomal peptide synthase -
Nodularia spumigena CCY 9414
Length = 1394
Score = 62.5 bits (145), Expect = 4e-08
Identities = 73/300 (24%), Positives = 132/300 (44%), Gaps = 31/300 (10%)
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFV-QPHEKN---NTMGK 144
+ F YG TE + S+A N K+ P+G ++++ H + G+
Sbjct: 820 QFFNAYGPTESTICTSIALCQPN-----GKKPPIGKPWPNIQIYILDAHHQPLPPGIPGE 874
Query: 145 IILASKTRKCILLNRKNGNKEE-------NSIKFI-DTGDIGEIR-NGTVFYRGRVDDTI 195
+ +A LNR E+ +K I TGD+ +G + Y GR+D+ +
Sbjct: 875 LCIAGVGLARGYLNRPELTAEKFIEVELFGKVKRIYKTGDLARWGIDGNLEYLGRIDEQV 934
Query: 196 KRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP--LLLIVYFSAETLS-SQELLDFLKCK 252
K G +I L IES ++Q P V+ + +T LI Y + T EL + LK +
Sbjct: 935 KLRGFRIELGEIESQLLQHPSVKEAVVILYKTESNQSLIAYVTGITHDLCPELRNHLKSR 994
Query: 253 LDEKYWPDKVIRVDTLPTNAHGKTSKEIL--VNIYKKSNILQNVENIKSYLFKELKALVN 310
L + P +++ +D LP +GK +++ L N+ + + ++ L + A++
Sbjct: 995 LPDYMIPAQIMVLDKLPLTPNGKINRKALPAPNVGVEGLYVAPRNEVEQQLEQLWSAVLE 1054
Query: 311 KD-LNYEDLQSKSFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTI 369
+ + D +FF LGG S LA+ + N + E G+ + L N +I + + +
Sbjct: 1055 RQKIGIHD----NFFDLGGHSLLAIKLLNNIQ---QEFGQQLALSSLFQNPTIAQLAEAL 1107
>UniRef50_UPI0000DB6BFA Cluster: PREDICTED: similar to ebony
CG3331-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
to ebony CG3331-PA - Apis mellifera
Length = 860
Score = 62.1 bits (144), Expect = 5e-08
Identities = 51/230 (22%), Positives = 100/230 (43%), Gaps = 19/230 (8%)
Query: 84 KNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN---- 139
+N+ + YG TE+ + L K ++VP+G L +++ +
Sbjct: 318 ENDSKILANFYGSTEIMGDVTYHLLTNRKQLQSVEKVPIGKPLDNCVIYIVNKDMRLIPQ 377
Query: 140 NTMGKIILASKTRKCILLNRKNGNKEENSIKFID--------TGDIGEIRNGTVFYRGRV 191
+G++I+A + ++ K +++ ID TGD +I G + Y GRV
Sbjct: 378 GEVGELIVAGRNLATGYIHNNESRKFQDNPYTIDLEYSRIYCTGDYAKISKGVIMYEGRV 437
Query: 192 DDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW-----LQTPLLLIVYFSAETLSSQELL 246
D IK GH+++L +E + + + + L L+ V + ++ + +
Sbjct: 438 DSQIKVRGHRVDLTEVEKVISRISEIDGVIVLCYKPGELSQSLVAFVTIAKDSSTCVSKI 497
Query: 247 DFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVEN 296
+ + Y +VI V+ +P +GKT ++ L+ Y+ SN+ N EN
Sbjct: 498 ETFLQSMLPIYMLPRVIIVENIPLLTNGKTDRQALLKYYESSNV--NNEN 545
>UniRef50_UPI000038CDA7 Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide
synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 1075
Score = 62.1 bits (144), Expect = 5e-08
Identities = 75/304 (24%), Positives = 133/304 (43%), Gaps = 31/304 (10%)
Query: 65 LALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGN 124
L LGGE N +++++++ + + IF YG TE + V + + + VPLG
Sbjct: 718 LILGGEAANW-QLIEQIQQQVPSSLIFNHYGPTEAT--VGVTTFAVEQQINHTQTVPLGR 774
Query: 125 CLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRK---------NGNKEENSI-- 169
L+ T++++ + G++ + LN+ N + I
Sbjct: 775 PLANTQIYLLDEQLQPVPVGVPGELYIGGAGLARGYLNQSDLTAAQFIPNPFADTGLIAS 834
Query: 170 ----KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW 224
+ TGD+ + +G + + GRVD +K G +I L IE+T+ Q P+V+
Sbjct: 835 KPGSRLYKTGDLARYLPDGNIEFLGRVDHQVKIRGFRIELGEIETTLCQHPQVQQAVASI 894
Query: 225 LQTPL---LLIVYF---SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS- 277
+ L+ Y +TLS EL FL+ KL E P I + LP +GK +
Sbjct: 895 REEEFGNKSLVAYVVPKQQQTLSVSELYRFLREKLPEYMMPATFIMLKALPLTPNGKVNR 954
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTI 336
+E+ + + + E ++ + + + + + L+ E + +FF LGG S L V I
Sbjct: 955 RELPESNGDRPELAATYEPPQTEIEQTIANIWQQMLHVEKVGIYDNFFDLGGHSLLLVQI 1014
Query: 337 CNKL 340
KL
Sbjct: 1015 HAKL 1018
>UniRef50_Q7VUT7 Cluster: Putative D-alanine-D-alanyl carrier
protein ligase; n=3; Bordetella|Rep: Putative
D-alanine-D-alanyl carrier protein ligase - Bordetella
pertussis
Length = 487
Score = 62.1 bits (144), Expect = 5e-08
Identities = 65/271 (23%), Positives = 119/271 (43%), Gaps = 24/271 (8%)
Query: 31 NSVTFWQTTPSKFFQHSNENIKNKILCARS--TLKVLALGGEPLNGIKILKELKHKNNKT 88
+ VT W +TPS F H + + N+ + L+ GEPL + + ++L+ + +
Sbjct: 218 SGVTVWVSTPS--FAH--QQLVNRDFSPQQLRALRTFLFCGEPLP-VALARKLRQRFPEA 272
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKNNTMGKIILA 148
I YG TE + + +D + V +P+G + L+V E +G ++
Sbjct: 273 AILNTYGPTEATVATTALVVD-DAVLAEHDPLPVGYAKPASLLYVADDEIC-IVGDYVMR 330
Query: 149 SKTRKCILLNRKNGNKEENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSI 207
+ L N+ + + TGD+G +R +G +F RGR+DD IK G++I L I
Sbjct: 331 GYLNRPDL-NQAKLFVHHDGRRGFRTGDLGRMREDGLLFCRGRMDDQIKLNGYRIELAEI 389
Query: 208 ESTVMQCPRVRSCSCVWLQTP---LLLIVYFSAETLSSQELLDF----------LKCKLD 254
++ + P V +C L+ P + ++ F A+ Q L +L
Sbjct: 390 DAALHALPGVAGGACAVLRRPDGTAVRVIGFVAQRTMEQASFQLPAALQQWKAQLTGRLP 449
Query: 255 EKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
P +++ LP + + K ++ L+ IY
Sbjct: 450 SYMVPSELVACPDLPVSNNHKIDRKKLLEIY 480
>UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4;
Photorhabdus luminescens subsp. laumondii|Rep: Complete
genome; segment 11/17 - Photorhabdus luminescens subsp.
laumondii
Length = 5457
Score = 62.1 bits (144), Expect = 5e-08
Identities = 67/299 (22%), Positives = 132/299 (44%), Gaps = 24/299 (8%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
+K+L GG+ + ++++ ++ + ++ YG +E + + ++ + +T G +P
Sbjct: 1617 IKILIFGGD-IPDLQVIAQVLNNRPPQQLLQAYGPSEGTTFTTM--YPIVALTQGVTRIP 1673
Query: 122 LGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKE---------EN 167
+G ++ T +++ QP T G+I + C LNR + E +
Sbjct: 1674 IGRPIANTRIYLLNAYGQPVPLGVT-GEIYVGGDGVACGYLNRPDQTAERFLTDPFSDQP 1732
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+ + +G + + GR D +K G +I IE+ +++ P VR + + L
Sbjct: 1733 DARMYRTGDLARYLPDGNLEFLGRNDQQVKIRGFRIEPGEIEARLVEHPAVREAAVLALG 1792
Query: 227 --TPLLLIVYFSAETLS--SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
+ L+ Y +AE + L D L L + P +R++ P +GK + L
Sbjct: 1793 DGSDKRLVAYVAAEAHEGLAMTLRDHLSAILPDYMVPSAFVRLEAFPLTPNGKLDRRALP 1852
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQS-KSFFSLGGTSFLAVTICNKL 340
+++ Q + + L + + L E + SFF+LGG S LAV + L
Sbjct: 1853 APDEEAFARQVYVAPQGEMEIALATIWRELLGIEQVSRYDSFFALGGHSLLAVRMVEHL 1911
Score = 54.4 bits (125), Expect = 1e-05
Identities = 46/173 (26%), Positives = 81/173 (46%), Gaps = 6/173 (3%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT--PLL 230
TGD+ + +G + + GR D +K G ++ L IE+ +++ P V+ + + L
Sbjct: 2816 TGDLARYLLDGELEFLGRNDQQVKIRGFRVELGEIETRLVEYPAVQEAAVLALDDGQDKR 2875
Query: 231 LIVYFSAETLS--SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L+ Y AE + L ++L L + P +R+D+ P +GK + L + +
Sbjct: 2876 LVAYVVAEANEGLAARLREYLSAVLPDYMIPVAFVRLDSFPQTPNGKLDRRALPAPGEAA 2935
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDLQS-KSFFSLGGTSFLAVTICNKL 340
Q E + + L A+ + L E + SFF+LGG S LAV + +L
Sbjct: 2936 FARQVYEAPQGKIETMLAAVWCELLGVEQISRYDSFFALGGHSLLAVRMIERL 2988
Score = 52.4 bits (120), Expect = 4e-05
Identities = 67/299 (22%), Positives = 127/299 (42%), Gaps = 24/299 (8%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
+K+L GG+ + +K++ ++ ++ YG +E + + ++ ++ + G +P
Sbjct: 3769 IKILIFGGD-IPDLKVIAQVLDNRPPQQLLQAYGPSEGTTFTTMYPIEA--LPQGVSRIP 3825
Query: 122 LGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSIK-FID-- 173
+G ++ T +++ QP +G+I + LNR E + F D
Sbjct: 3826 IGRPIANTRVYLLDVYGQPVPPG-VIGEIYVGGDGVAQGYLNRPELTAERFLVDPFSDDP 3884
Query: 174 ------TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL- 225
TGD+ + +G + + GR D +K G +I IE+ +++ P VR + + L
Sbjct: 3885 DARMYRTGDLARYLPDGNLEFMGRNDQQVKIRGFRIEPGEIEARLVEHPAVREAAVLALG 3944
Query: 226 ---QTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
L+ V A+ L +L L + P +R+D P +GK + L
Sbjct: 3945 DGPDKRLVAYVVALADDGLVNSLRAYLSKILPDYMVPSAFVRLDAFPLTPNGKLDRRALP 4004
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQS-KSFFSLGGTSFLAVTICNKL 340
++ Q + L A+ + L E + SFF+LGG S LAV + +L
Sbjct: 4005 APDSEAFARQVYVAPQGETEMTLAAIWCELLGIEQVSRYDSFFALGGHSLLAVRMIERL 4063
Score = 49.2 bits (112), Expect = 4e-04
Identities = 44/173 (25%), Positives = 78/173 (45%), Gaps = 6/173 (3%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--L 230
+GD+ + +G + + GR D+ +K G +I L IE+ + + P V+ + + L
Sbjct: 667 SGDLARYLPDGDLEFLGRNDEQVKIRGFRIELGEIETRLTEHPAVQEAAVLALDGDQGKR 726
Query: 231 LIVYFSAETLS--SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L+ Y A+ + +L ++L L + P +R+DT P GK + L +
Sbjct: 727 LVAYVEAKANEGLAVDLREYLSAILPDYMVPAAFVRLDTFPQTPSGKLDRRALPAPGEND 786
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
Q E + L + + L E + + SFF+LGG S L V + +L
Sbjct: 787 FARQIYEAPQGKAEITLADIWRELLGIEQISRHDSFFALGGHSLLGVQMIERL 839
Score = 43.2 bits (97), Expect = 0.027
Identities = 42/171 (24%), Positives = 74/171 (43%), Gaps = 6/171 (3%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL----QTP 228
TGD+ + +G + + GR D +K G ++ IE+ +++ P V + L
Sbjct: 4969 TGDLVRYLPDGNLEFLGRNDHQVKIRGFRVEPGEIEARLVEHPAVSQSVVLALGEGQDKR 5028
Query: 229 LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L+ V A+ + L L L + P +R+D P +GK + L ++
Sbjct: 5029 LVAYVVAQADERLANSLRTHLSAILPDYMVPSAFVRLDAFPLTPNGKLDRRALPEPDNEA 5088
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICN 338
Q E + L A+ + L E + + +FF+LGG S LA+ + N
Sbjct: 5089 FARQAYEAPQGETEIVLAAIWCELLGIEQVSRHDNFFALGGHSLLAMRMMN 5139
>UniRef50_Q62C03 Cluster: Nonribosomal peptide synthetase DhbF; n=18;
Burkholderia|Rep: Nonribosomal peptide synthetase DhbF -
Burkholderia mallei (Pseudomonas mallei)
Length = 1082
Score = 62.1 bits (144), Expect = 5e-08
Identities = 81/337 (24%), Positives = 140/337 (41%), Gaps = 27/337 (8%)
Query: 30 DNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKEL-KHKNNKT 88
D VT TPS F Q + + L AR L+ + GGE L+ + + +H +
Sbjct: 710 DERVTVLNQTPSAFRQLMQADEAHADLSARLALRYVVFGGEALDARSLARWYERHADTAP 769
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL-GNCLSETELFVQPHEKN----NTMG 143
R+ +YG+TE + V+ L L++ G L G L + ++V G
Sbjct: 770 RLVNMYGITETT--VHVSYLALSRAIAGMPANSLIGRPLPDLRVYVLDAALRPVPAGVPG 827
Query: 144 KIILASKTRKCILLNRKNGNKEE--------NSIKFIDTGDIGEIR-NGTVFYRGRVDDT 194
++ +A L R + + + TGD+ R +G + + GR D+
Sbjct: 828 EMYVAGAGLARGYLRRPSLTAQRFIADPFGPPGTRMYRTGDVARWRADGGLDFIGRADEQ 887
Query: 195 IKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT-PL--LLIVYF---SAETLSSQELLDF 248
+K G ++ L I + + P V V Q P L+ Y + T+ L
Sbjct: 888 VKVRGFRVELGEIAARLACDPSVAQAQAVVRQDGPAHERLVAYVVPRAGATIDVCALRAS 947
Query: 249 LKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKAL 308
L ++ E P ++ +D +P +GK + L + EN + +++ A+
Sbjct: 948 LAAEMPEYMVPAAIVALDAMPLTPNGKLDRAALPAPIVTGTSRRAPEN---RIEQQVCAM 1004
Query: 309 VNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKLSLTF 344
+ L+ + L ++ +FF LGG S LA+ NKL TF
Sbjct: 1005 FAELLDAQTLGAEDNFFELGGDSLLAMRAINKLRQTF 1041
>UniRef50_Q4BYH7 Cluster: Thioesterase:Phosphopantetheine-binding;
n=2; cellular organisms|Rep:
Thioesterase:Phosphopantetheine-binding - Crocosphaera
watsonii
Length = 570
Score = 62.1 bits (144), Expect = 5e-08
Identities = 58/213 (27%), Positives = 99/213 (46%), Gaps = 18/213 (8%)
Query: 174 TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV-RSCSC-----VWLQ 226
TGD G + G + GRVDD I R G KI ++E + Q P V R+C ++ Q
Sbjct: 136 TGDWGSLDETGGLQIMGRVDDRINRGGQKIAPKAVERILEQHPYVKRACVFGIPHEIFGQ 195
Query: 227 TPLLLIVYFSAET--LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
I+ S +T EL ++ +L P++++ V+ PTN GK ++ LV +
Sbjct: 196 QVAAAIILHSDQTKIFKENELRAYVAGELPNYMVPEEILCVEAFPTNLVGKLDRQALVTL 255
Query: 285 YKKSNILQNVENIKSYLF-----KELKALVNKDLNYEDLQSKS-FFSLGGTSFLAVTICN 338
++ I + YL K L+ + + L ++ ++ F +LGG SF A+++
Sbjct: 256 VQQKQIEAEQKRQGRYLANSFPEKRLREIYQELLQISEIDLEADFAALGGDSFQAMSLLI 315
Query: 339 KLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQ 371
++ F G + P + SI + K +TQ
Sbjct: 316 EIEDRF---GTLLTPEQFLQHSSIEALAKLLTQ 345
>UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Putative
non-ribosomal peptide synthetase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 2385
Score = 62.1 bits (144), Expect = 5e-08
Identities = 75/331 (22%), Positives = 131/331 (39%), Gaps = 25/331 (7%)
Query: 30 DNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKEL-KHKNNKT 88
++ VT TPS F + S + L+V+ GGE L ++ +H ++
Sbjct: 698 EHRVTVLNQTPSAFEELSRADADAPGTAL--ALRVVVFGGEALEPTRLASWYERHGDSTP 755
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEK--NNTMGKII 146
+ +YG+TE + S LD + T+ + G T L + + +G++
Sbjct: 756 LLVNMYGITETTVHVSYLALDGSHATSPASAIGRGLPGLSTYLLDEALRPVPDGVVGELY 815
Query: 147 LASKTRKCILLNRKNGNKEE--------NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKR 197
+ L R + TGD+ +G + Y GR DD +K
Sbjct: 816 VGGAQLARGYLGRPGLTATRFVADPFGAPGERLYRTGDLARRAGDGRLEYVGRADDQVKI 875
Query: 198 FGHKINLHSIESTVMQCPRVRSCSCV---WLQTPLLLIVYFSAETLSSQELLDFLKCKLD 254
G +I I S + P V C+ V Q L+VY E++ L +L +L
Sbjct: 876 RGFRIEPAEISSVLATHPDVSRCAVVARHGAQGGAYLVVYVVGESVDPAALRGYLAARLP 935
Query: 255 EKYWPDKVIRVDTLPTNAHGKTSKEILV-----NIYKKSNILQNVENIKSYLFKELKALV 309
E P + +++LP +GK + L + + E + + LF + ++
Sbjct: 936 EHMVPAAFVELESLPLTGNGKLDRRALPAPEFGSTAPSREPATDTERVLAELFAD---VL 992
Query: 310 NKDLNYEDLQSKSFFSLGGTSFLAVTICNKL 340
+D +SFFSLGG S LA + +++
Sbjct: 993 GRDEGTPVGVDESFFSLGGHSLLATRLVSRI 1023
Score = 51.6 bits (118), Expect = 8e-05
Identities = 51/203 (25%), Positives = 89/203 (43%), Gaps = 12/203 (5%)
Query: 174 TGDIG-EIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--- 229
TGD+ GT+ +RGR D +K G ++ L +ES + + P VR V ++
Sbjct: 1911 TGDLACWTAGGTLEFRGRADHQVKIRGMRVELQEVESVLSEHPAVRQAVVVTARSRSDVG 1970
Query: 230 LLIVYFSA--ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK 287
LL+ Y + E+++ L +L+ +L E P V+ + P GK + L
Sbjct: 1971 LLVAYCTTTDESVTGDGLRGWLRGRLPEHMVPAAVVCLPRFPLMPSGKVDRRSLPMPELG 2030
Query: 288 SNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLSLTFPE 346
S + + + K L AL + L + + SFF LGG S LA + ++ E
Sbjct: 2031 SAVA--YRDPATPTEKALSALFGEILGVDRVGADDSFFELGGYSLLATRLVARVQ---AE 2085
Query: 347 VGKHILPHLLSHNKSIGDVLKTI 369
+G + + ++ D+ + I
Sbjct: 2086 LGVEVALRTVFDAPTVADLARII 2108
>UniRef50_A3KFG5 Cluster: PstC protein; n=2; Actinomycetales|Rep: PstC
protein - Actinoplanes friuliensis
Length = 6661
Score = 62.1 bits (144), Expect = 5e-08
Identities = 88/355 (24%), Positives = 151/355 (42%), Gaps = 35/355 (9%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S L VL +GGE L + ++L + + LYG TE + W++VAE++ + T G
Sbjct: 2762 SALHVL-VGGEALPS-DLARDLHER--AASVTNLYGPTETTVWSTVAEVEPGRSTIG--- 2814
Query: 120 VPLGNC-LSETELFVQPHEKNNTMGKIILASK-------TRKCILLNRKNGNKEENS-IK 170
P+ N + + ++P G++ +A R + R N + +
Sbjct: 2815 TPIANTQVYVLDAALRPVPAG-VPGEVYIAGDGVVRGYWQRPALTAQRFVANPYGTTGSR 2873
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPR-VRSCSCVWLQTP 228
F TGDIG +GT+ Y R DD +K G++I L IE+ + P V++ V P
Sbjct: 2874 FYRTGDIGRWAADGTLEYLSRADDQVKLRGYRIELGEIEAVLAADPAVVQAAVLVREDRP 2933
Query: 229 --LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL-VNIY 285
L+ Y S+ L + + L E P ++ +DT P +GK ++ L Y
Sbjct: 2934 GDKRLVAYVRG---SADGLRERIARSLPEYMVPAAIVELDTFPLTPNGKLNRRALPAPDY 2990
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
+ + N + L L A V L E + FF+LGG S LA + +++
Sbjct: 2991 GVESAGRQPRNPREELLCGLFAEV---LGVESVGIDDDFFALGGHSLLATRLISRIRSV- 3046
Query: 345 PEVGKHILPHLLSHNKSIGDVLKTITQDTN-CLENKFKKSIKRNRSTSSHGENSI 398
+G + L ++ + T DTN + + + +R S+G+ +
Sbjct: 3047 --LGAEVAVRRLFETPTVAGLAATF--DTNAAARTRITPAARPDRVPLSYGQRRL 3097
Score = 54.8 bits (126), Expect = 8e-06
Identities = 76/296 (25%), Positives = 123/296 (41%), Gaps = 29/296 (9%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S L VL +GGE L + ++L + + LYG TE + W++VA++D ++ T G
Sbjct: 4804 SALHVL-VGGEALPS-DLARDLHTR--AASVTNLYGPTETTVWSTVADVDPDRSTIGS-- 4857
Query: 120 VPLGNC-LSETELFVQPHEKNNTMGKIILASK-------TRKCILLNRKNGNKEENS-IK 170
P+ N + + ++P G++ +A R + R N + +
Sbjct: 4858 -PIANTQVYVLDAALRPVPAG-VAGEVYIAGDGVVRGYWQRPGLTAQRFVANPYGTTGSR 4915
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT-- 227
F TGDIG +G + Y R DD +K GH+I L IE+ + V + + +
Sbjct: 4916 FYRTGDIGRWAADGMLEYLSRADDQVKLRGHRIELGEIEAVLAADAAVAQAAVIVREDRP 4975
Query: 228 -PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL-VNIY 285
L+ Y S+ L D L P + +DT P +GK + L Y
Sbjct: 4976 GDKRLVAYVRG---SADGLRDRAAAALPGYMVPAAFVELDTFPLTPNGKLDRRALPAPEY 5032
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
+ N + L L A V L E + FF+LGG S LA + +++
Sbjct: 5033 DVEGTGRRPRNPREELLCGLFAEV---LGVESVGIDDDFFALGGHSLLATRLISRI 5085
Score = 46.0 bits (104), Expect = 0.004
Identities = 47/193 (24%), Positives = 86/193 (44%), Gaps = 22/193 (11%)
Query: 174 TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP---- 228
TGD+ +G + + GRVDD +K G ++ IE+ + Q P V + + +
Sbjct: 5964 TGDVVSWDADGRLIFAGRVDDQVKLRGFRVEPGEIEAVLRQRPEVAEAAVILREDRPGDK 6023
Query: 229 --LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL-VNIY 285
+ +V +A + +L + L + P V+ VD LP A+GK + L V +
Sbjct: 6024 RLVAYVVTAAAFSAHPDDLRRHVAATLPDYLVPSAVVLVDVLPLTANGKLDRAALPVPEF 6083
Query: 286 KKSN---ILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNK--- 339
S+ E + + LF E+ + ++ + FF LGG S +++ + ++
Sbjct: 6084 GGSSGRGPRDEREKVLAALFAEVLGVAEVGVD------EGFFDLGGDSIMSIQLVSRARR 6137
Query: 340 --LSLTFPEVGKH 350
L L+ EV +H
Sbjct: 6138 AGLELSVREVFEH 6150
>UniRef50_Q04747 Cluster: Surfactin synthetase subunit 2; n=9;
Bacillus|Rep: Surfactin synthetase subunit 2 - Bacillus
subtilis
Length = 3587
Score = 62.1 bits (144), Expect = 5e-08
Identities = 75/322 (23%), Positives = 131/322 (40%), Gaps = 20/322 (6%)
Query: 26 HEDNDNSVTFWQTTPSKFFQHSNENIKNKILCAR-STLKVLALGGEPLNGIKILKELKHK 84
H ++ +T+ + TPS F H+ N + A +L+++ LGGE + ++ K
Sbjct: 1727 HYIKEHGITYIKLTPSLF--HTIVNTASFAFDANFESLRLIVLGGEKIIPTDVIAFRKMY 1784
Query: 85 NNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----N 140
+ T YG TE + A +DL + K +G ++ V
Sbjct: 1785 GH-TEFINHYGPTEATIGAIAGRVDLYEPDAFAKRPTIGRPIANAGALVLNEALKLVPPG 1843
Query: 141 TMGKIILASKTRKCILLNRKNGNKE---ENSIK----FIDTGDI-GEIRNGTVFYRGRVD 192
G++ + + LNR E EN TGD+ + +GT+ + GR D
Sbjct: 1844 ASGQLYITGQGLARGYLNRPQLTAERFVENPYSPGSLMYKTGDVVRRLSDGTLAFIGRAD 1903
Query: 193 DTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ---TPLLLIVYFSAETLSSQELLDFL 249
D +K G++I L IE+ ++ ++ + + L Y S + + EL L
Sbjct: 1904 DQVKIRGYRIELGEIETVMLSLSGIQEAVVLAVSEGGLQELCAYYTSDQDIEKAELRYQL 1963
Query: 250 KCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALV 309
L P ++VD +P A+GKT + L + + + ++ L + L +
Sbjct: 1964 SLTLPSHMIPAFFVQVDAIPLTANGKTDRNALPKPNAAQSGGKALAAPETALEESLCRIW 2023
Query: 310 NKDLNYEDLQ-SKSFFSLGGTS 330
K L E + +FF LGG S
Sbjct: 2024 QKTLGIEAIGIDDNFFDLGGHS 2045
Score = 50.8 bits (116), Expect = 1e-04
Identities = 69/298 (23%), Positives = 130/298 (43%), Gaps = 31/298 (10%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
++L+VL GG+ L + K NN YG TE + A+ AE+ +
Sbjct: 2802 TSLRVLLTGGDKLKRA-VKKPYTLVNN-------YGPTENTVVATSAEIHPE-----EGS 2848
Query: 120 VPLGNCLSETELFVQPH----EKNNTMGKIILASKTRKCILLNRKNGN-KEENSIKFID- 173
+ +G ++ T +++ + G++ +A + LNR++ K + F+
Sbjct: 2849 LSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYLNREDETAKRFVADPFVPG 2908
Query: 174 -----TGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP 228
TGD+ + NG + Y GR+D +K G++I L IE + Q V + ++
Sbjct: 2909 ERMYRTGDLVKWVNGGIEYIGRIDQQVKVRGYRIELSEIEVQLAQLSEVEDRAVTRVKDK 2968
Query: 229 ---LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
+ Y + ET + L LK L + P + ++ LP A+GK ++ L
Sbjct: 2969 GGNTAIAAYVTPETADIEALKSTLKETLPDYMIPAFWVTLNELPVTANGKVDRKALPEPD 3028
Query: 286 KKSNILQNVENIKSYLFKELKALVNKD-LNYEDL-QSKSFFSLGGTSFLAVTICNKLS 341
++ + +EL A + +D L ++ + +FFSLGG S + + ++L+
Sbjct: 3029 IEAG--SGEYKAPTTDMEELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLN 3084
Score = 48.4 bits (110), Expect = 7e-04
Identities = 65/296 (21%), Positives = 130/296 (43%), Gaps = 14/296 (4%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
TL+ L +GG+ L I+ ++K + ++ YG TE + +++ +D +
Sbjct: 720 TLRHLIIGGDALVP-HIVSKVKQASPSLSLWNGYGPTENTTFSTSFLIDREYGGSIPIGK 778
Query: 121 PLGNC---LSETELFVQPHEKNNTM--GKIILASKTRKCILLNRKNGNKE--ENSIKFID 173
P+GN + + + +QP + G I +A L K ++ +
Sbjct: 779 PIGNSTAYIMDEQQCLQPIGAPGELCVGGIGVARGYVNLPELTEKQFLEDPFRPGERIYR 838
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--- 229
TGD+ + +G + + GR+D+ +K G +I L IE+ + V + + +
Sbjct: 839 TGDLARWLPDGNIEFLGRIDNQVKVRGFRIELGEIETKLNMAEHVTEAAVIIRKNKADEN 898
Query: 230 LLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
+ YF+A+ ++ EL L L + P +I++D+LP +GK +K+ L ++
Sbjct: 899 EICAYFTADREVAVSELRKTLSQSLPDYMVPAHLIQMDSLPLTPNGKINKKELPAPQSEA 958
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTF 344
+ K+ K+L + L + + +FF +GG S A+ + K+ F
Sbjct: 959 -VQPEYAAPKTESEKKLAEIWEGILGVKAGVTDNFFMIGGHSLKAMMMTAKIQEHF 1013
>UniRef50_Q311J0 Cluster: Amino acid adenylation; n=2; Bacteria|Rep:
Amino acid adenylation - Desulfovibrio desulfuricans
(strain G20)
Length = 3252
Score = 61.7 bits (143), Expect = 7e-08
Identities = 65/263 (24%), Positives = 108/263 (41%), Gaps = 22/263 (8%)
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKNNT----MGK 144
RIF++ G TE + W+ + D ++ G + VP G L +L V + G+
Sbjct: 1873 RIFSMGGATEAAIWS--VKYDTAQLPQGSRTVPYGTPLPNQKLMVLDEQLEIAPAWVTGE 1930
Query: 145 IILASKTRKCILLNRKNGNKEE------NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKR 197
+ + K LN + + TGD+G + +GT+ + GR D +K
Sbjct: 1931 LHIGGKGLALGYLNDPEKTAAQFIRHPRTGERLYKTGDLGRYLPDGTIEFIGRKDAQVKI 1990
Query: 198 FGHKINLHSIESTVMQCPRVRSCSCVWLQT---PLLLIVYFSAETLSSQELLDFLKCKLD 254
GH++ IE +++ P V + + + P L + T + EL FL+ L
Sbjct: 1991 RGHRVEPGEIEHCLLRHPAVHKAAVIAVGDAGKPRSLAAF--VVTTAHDELRAFLRSNLP 2048
Query: 255 EKYWPDKVIRVDTLPTNAHGKTSKEILVN-IYKKSNILQNVENIKSYLFKELKALVNKDL 313
E P ++I V LP +GK ++ L I + + + L + A V L
Sbjct: 2049 EHMVPSQIIAVPALPLTENGKLDRKALQRMIPAREDRNAATAGPEQQLLGSIWAAV---L 2105
Query: 314 NYEDLQSKSFFSLGGTSFLAVTI 336
+ SFF GG S LA +
Sbjct: 2106 GQQTDIDTSFFEAGGDSLLATRV 2128
Score = 47.2 bits (107), Expect = 0.002
Identities = 43/175 (24%), Positives = 79/175 (45%), Gaps = 10/175 (5%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLL-- 230
TGD+ +R G + + GR D +K GH++ L IE+ + P+++ + + L +
Sbjct: 3020 TGDLARVRPEGFIEFLGREDQQVKIRGHRVELGEIENALTLHPQIKE-ALITLHGESISG 3078
Query: 231 --LIVYFSAETL--SSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L+ Y + + +++EL D L L PD + P A+GK + L +
Sbjct: 3079 KRLLAYLTVQQQPPAAEELRDHLAQVLPRFMIPDHFFFLTEFPVTANGKIDHKAL-PLPS 3137
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYED-LQSKSFFSLGGTSFLAVTICNKL 340
+ V+ S L + L+ + L + L +FF +G +SF V + N +
Sbjct: 3138 EEQATHAVQTGGSDLVQALQGYLAAALESQAVLPDANFFDMGVSSFHLVQVQNDI 3192
>UniRef50_Q2AZG3 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=16; Bacteria|Rep: Non-ribosomal peptide
synthase:Amino acid adenylation - Bacillus
weihenstephanensis KBAB4
Length = 4968
Score = 61.7 bits (143), Expect = 7e-08
Identities = 68/303 (22%), Positives = 134/303 (44%), Gaps = 23/303 (7%)
Query: 60 STLKVLALGGEPLNG--IKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
S+L + GE LN ++ K + + +T++ LYG TE + + + DL K
Sbjct: 752 SSLNQVFTSGEALNTEQVRRFKGVFYDVQQTKLINLYGPTEATVDVTYYDCDLEKEPM-- 809
Query: 118 KEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE-------E 166
+P+G + TEL+V + G++ L NR E +
Sbjct: 810 -LIPIGRPIDNTELYVLDQYQQVVPIGVAGELYLGGVGLARGYFNRPELTTERFIPHPFK 868
Query: 167 NSIKFIDTGDIGEIRNG-TVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
+ TGD+ N + Y GR+D+ +K G +I L IE+ + V+ +
Sbjct: 869 EGERLYRTGDLVRYMNDRNLEYIGRIDNQVKIRGFRIELGEIEAALHDHSSVKEAVVLVK 928
Query: 226 QT---PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
+ L+ Y E + E ++LK +L P +V+++P +GK ++ L+
Sbjct: 929 EDRPGDKQLVAYVVGEG-DTGEWREYLKKQLPNYMVPAYFFQVESMPLTPNGKVDRKALL 987
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKLS 341
+ + I +++ + ++ + + + ++ +K L ++ + SFF +GG S LA + ++L
Sbjct: 988 EL-EAQFISEDITSSRTPVEELIVSVWSKVLGIRNISVQDSFFEIGGHSLLATQVVSRLQ 1046
Query: 342 LTF 344
F
Sbjct: 1047 EIF 1049
Score = 57.2 bits (132), Expect = 2e-06
Identities = 81/355 (22%), Positives = 147/355 (41%), Gaps = 19/355 (5%)
Query: 30 DNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTR 89
+N + + TPS +E + KVL +GGE + + L E +N+
Sbjct: 4351 ENKLEMFDITPSLLQLLIDEGLLETNDSVHVPSKVL-VGGEAI--MPSLWEQLVENDHIH 4407
Query: 90 IFTLYGVTEMSCWASVAEL--DLNKVTTGDKEVPLGNCLSETELFVQPHEKNNTM--GKI 145
+ +YG TE + A+ + D +VT G + + + +L P + G
Sbjct: 4408 FYNVYGPTECTVDATCYRIKKDSKRVTIGRPLPNVQAYVLDEKLLPVPVGVTGELYIGGA 4467
Query: 146 ILASK--TRKCILLNRKNGNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKI 202
LA R + L R + + TGD+ + +G + Y GR+D+ +K G +I
Sbjct: 4468 GLARGYLNRPELTLERFIPHPFNEGERLYRTGDLVRYLADGHLDYLGRIDNQVKIRGFRI 4527
Query: 203 NLHSIESTVMQCPRVRSCSCVWLQT---PLLLIVYFSAETLSSQELLDFLKCKLDEKYWP 259
L IE+ + P V+ + + L+ Y E S E + LK ++ P
Sbjct: 4528 ELGEIEANLESHPSVKEAVVLIREDQPGDQRLVAYVVGEG-SMHEWREHLKRQVPNHMIP 4586
Query: 260 DKVIRVDTLPTNAHGKTSKEILVNI-YKKSNILQNVENIKSYLFKELKALVNKDLNYEDL 318
I VD +P +GK ++ L ++ ++ N + + +L + L ED+
Sbjct: 4587 AHFIEVDAIPLTTNGKVDRKALNSLTIQRENTFSTPIIPRDEIEYQLITIWQDLLQLEDI 4646
Query: 319 Q-SKSFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQD 372
+ FF++GG S L + + +K+ F GK I L N ++ + I ++
Sbjct: 4647 HVNDDFFNIGGHSLLVIKLISKVREKF---GKEIKVPALIKNPTVEGIACLIREN 4698
Score = 54.4 bits (125), Expect = 1e-05
Identities = 62/248 (25%), Positives = 111/248 (44%), Gaps = 21/248 (8%)
Query: 113 VTTGDKEVPLGNCLSETELFV-QPHEK---NNTMGKIILASKTRKCILLNRKNGNKEE-- 166
VTTG + G ++ TE++V H + + +G + + K+ NR + KE+
Sbjct: 1850 VTTGTPSI--GRPIANTEVYVLDSHLQLVPSGVIGDLYIGGKSLARGYANRPDLTKEKFI 1907
Query: 167 -----NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSC 220
+ + TGD + +G + + GR+DD +K G +I L IE+ + V+
Sbjct: 1908 SHPFKSGERLYYTGDKASYLSDGALQFHGRIDDQVKIRGFRIELGEIEAVLQAHSSVKEA 1967
Query: 221 SCVWLQT---PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ + L+ Y E S QE + L+ L P I ++ LP +GK
Sbjct: 1968 VVLVREDDPGDKRLVAYVVGEG-SVQEWREHLQTHLPNYMVPTNFIEMEFLPLTPNGKLD 2026
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTI 336
+ L K S +N + ++ L + + ++ ++ L E++ SFF LGG S LA +
Sbjct: 2027 LKALPIPSKLST--ENTVHARTPLEELIASVWSQVLGIENIGVQDSFFELGGHSLLATQV 2084
Query: 337 CNKLSLTF 344
++L F
Sbjct: 2085 VSRLQEVF 2092
Score = 51.6 bits (118), Expect = 8e-05
Identities = 60/330 (18%), Positives = 139/330 (42%), Gaps = 26/330 (7%)
Query: 62 LKVLALGGEPLNGIKILKEL-KHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
L+ + GGE L+ ++ ++ + ++ +YG+TE + + + + V +
Sbjct: 2857 LRYVIFGGEALDPTSLVPWFQRYGGQEPQLINMYGITETTVHVTYYPITQDDVQHASRS- 2915
Query: 121 PLGNCLSETELFV----QPHEKNNTMGKIILASKTRKCILLNRKNGNKE---------EN 167
+G + + E++V Q G++ + LNR E +
Sbjct: 2916 NIGKQIPDLEVYVLDACQQPVPIGVAGELFIGGAGLARGYLNRSELTAERFIPHPFSSDP 2975
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+ + +G + Y GR+D +K G +I L IES + ++ + +
Sbjct: 2976 GARLYRTGDLARYLPDGNLDYLGRIDHQVKIRGFRIELGEIESALNAHVSIKEAVVIVRE 3035
Query: 227 T---PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L+ Y + + E D+LK +L P + ++ +P A+GK ++ L
Sbjct: 3036 DQPGDKRLVAYVVGDG-NVGEWRDYLKAELPSHMVPSGFVMMEAIPLTANGKVDRKAL-P 3093
Query: 284 IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSL 342
+ ++ I ++ + L + + L + + +FF +GG S L++ I ++
Sbjct: 3094 VPEERKIESECVATRNGNEETLATIWKQVLGIKKVGIHDNFFEIGGDSILSIQIVSRAK- 3152
Query: 343 TFPEVGKHILPHLLSHNKSIGDVLKTITQD 372
+ G + P + +++I ++ + + ++
Sbjct: 3153 ---QAGLQLTPKQMFEHQTIAELAQVVNEE 3179
>UniRef50_Q2AZ45 Cluster: Amino acid adenylation; n=2; Bacillus cereus
group|Rep: Amino acid adenylation - Bacillus
weihenstephanensis KBAB4
Length = 2439
Score = 61.7 bits (143), Expect = 7e-08
Identities = 103/469 (21%), Positives = 185/469 (39%), Gaps = 51/469 (10%)
Query: 3 EILLACTNGASLLIAPD---LTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCAR 59
EI NGA L + D + V + + P+ FF + ++
Sbjct: 1638 EIFSTLLNGAELYLLSDEQRYSTVAYAQAIQEIQATLSDVPTVFFNELSTSLTKLDSEKI 1697
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELD-LNKVTTGDK 118
+L+ + +GGE + I N+ ++ YG TE + A + L +
Sbjct: 1698 RSLRFMIMGGEAASTNAIRSWQNTFKNQVQLVNEYGPTEATVSAMYYFIPILEDENSLLG 1757
Query: 119 EVPLGNCLSETELFV----QPHEKNNTMGKIILAS------------KTRKCILLNRKNG 162
+P+G +S T++ + H MG++ + S KT + + +
Sbjct: 1758 NIPIGIPISNTKVHILNSYMQHCPVGGMGELYIESLGLAQGYWKQEEKTNQAFI---SSP 1814
Query: 163 NKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
E+NS + TGD+ + + NG + + GR D +K GH+I L IE ++Q +
Sbjct: 1815 FSEDNSKRVYRTGDLAKWLPNGNIEFMGRKDKQVKIRGHRIELGEIEDALLQFEGISQAV 1874
Query: 222 CVWLQTPLLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
+ +LL Y+ + +L L L E P V +P A+GK
Sbjct: 1875 ITQTKDGMLLQAYYKTVDGIEIEKNKLAIHLSNVLPEYMIPKYYSHVLEIPITANGKIDF 1934
Query: 279 EILVNI-----YKKSNILQNVENIKSYLFKELKALVN-KDLNYEDLQSKSFFSLGGTSFL 332
E L I K IL+ ++ + K ++N K + +D FF+LGG S
Sbjct: 1935 EKLPEIDFDNEQKDDCILKPQTKVQKNIAKVWSEVLNIKSIGLKD----DFFNLGGHSLK 1990
Query: 333 AVTICNKLSLTFPEV------GKHILPHLLSHNKSIGDVLKTITQDTN--CLENKFKKSI 384
+ KL +P + + +L H + + D+ ++ N C+EN+ K +
Sbjct: 1991 VMPALVKLKPLYPNLKIQDFFKYRTIENLAYHIEEMEDMSLKNEKNINVACIENETKTNP 2050
Query: 385 KRNRSTSSHGE-NSISYKK-----GAGGIRNSNTVEFVVQWTFDTGKCV 427
R+ E + ++Y K GA G ++ +E ++Q T C+
Sbjct: 2051 VYKRTKLEECELDMVNYPKAVFLTGATGYLGAHILEQLLQLPSTTIYCL 2099
Score = 39.1 bits (87), Expect = 0.43
Identities = 25/105 (23%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
Query: 29 NDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKT 88
N N +T+ P+ FF+ + K +L S LK + +GGE + + K K
Sbjct: 697 NKNGITY-VLLPTAFFKLIADMPKEMLLTLNS-LKCVFVGGETIPAESVRKWQSKLGLKI 754
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFV 133
+ YG TE + ++ E++ +++ + +P+G ++ +++FV
Sbjct: 755 PVLNAYGPTEATVCTTIYEVN-HEIKEENSNIPIGKPIANSKVFV 798
>UniRef50_Q0YRE6 Cluster: Amino acid adenylation; n=1; Chlorobium
ferrooxidans DSM 13031|Rep: Amino acid adenylation -
Chlorobium ferrooxidans DSM 13031
Length = 4189
Score = 61.7 bits (143), Expect = 7e-08
Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 9/183 (4%)
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP- 228
F +GD G G + GR+D +K G ++ IE + P V + + Q
Sbjct: 1434 FYRSGDYGRWSAEGQLEINGRIDQQVKLNGQRVEPGEIEQMLSLHPAVVNAVVLADQLNN 1493
Query: 229 --LLLIVYFSAETL---SSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
+L + E + S ELL++L +L + P ++ V+ +P N GK +E L
Sbjct: 1494 GVKVLRAFVQPENIALFSESELLEYLAGRLPQHMVPASIMAVEAIPLNPSGKIDREQLFR 1553
Query: 284 IYKKSNILQNVENIK-SYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLS 341
K+ E++ S + +++ + + L +E + S +FF+LGG S LAVT+ +++S
Sbjct: 1554 YAKEQRRSAVQEDVPGSPIEQQIGNIWAEVLGHERVVGSDNFFALGGNSLLAVTVAHRIS 1613
Query: 342 LTF 344
TF
Sbjct: 1614 RTF 1616
Score = 61.3 bits (142), Expect = 9e-08
Identities = 76/295 (25%), Positives = 125/295 (42%), Gaps = 19/295 (6%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S+L+VL GGE + E+K +K F YG TE + +++ L +++
Sbjct: 2375 SSLRVLVTGGEA----PLPAEVKRYASKLSYFNAYGPTENTITSTMGLLKGDELRFFAAG 2430
Query: 120 VPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEE----NSIKFIDTG 175
PL N + G+I L + LNR +S + TG
Sbjct: 2431 RPLPNTALYICNEAGDYLPPGVSGEIRLGGEGISQGYLNRPELTAASFLGTSSGRLYRTG 2490
Query: 176 DIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP------ 228
D+G R+GTV GR+DD +K G +I L IE + P + S + V L P
Sbjct: 2491 DLGRWHRDGTVEIIGRIDDQVKLNGIRIELGEIEYALTMHPAI-SQAVVLLDAPSGGSKS 2549
Query: 229 LLLIVYFS--AETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L +V + E EL FL +L P VI V+++P GK + L+ + +
Sbjct: 2550 LWGVVRLTPGEEMPGRDELKTFLAERLPSHMIPSGVISVESIPLMVSGKVDRVALLALLE 2609
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + L + + + + L + + +FF+LGG S LA+ + ++L
Sbjct: 2610 DHPFSSGLTPPEDELERCIAGIWSDLLRRSPIHREDNFFALGGHSLLAIAVAHRL 2664
Score = 51.6 bits (118), Expect = 8e-05
Identities = 53/202 (26%), Positives = 88/202 (43%), Gaps = 22/202 (10%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL----QTP 228
TGD+G +R+G + GR D +K G ++ L IE + P ++ V T
Sbjct: 3545 TGDLGRWLRSGELQILGRADSQVKLRGQRVELGEIEHRLASRPGIQQAVAVVETLADSTQ 3604
Query: 229 LL---LIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
L ++V AE SS+E L +L L P ++R+ LP GK ++ L+++
Sbjct: 3605 RLCSFVVVDEQAEMPSSREWLSWLSATLPSYMIPASIVRIAALPLTPAGKVDRQALLDLQ 3664
Query: 286 KK-----------SNILQNVENIKSYLFKELKALVNKDLNYEDL--QSKSFFSLGGTSFL 332
+ + L +S K + A V +L + L + +SFF LGG S
Sbjct: 3665 AEMALSLDEGITDTTTLSQRTPPQSATEKRI-AEVWSELLRKPLVAREESFFELGGDSLR 3723
Query: 333 AVTICNKLSLTFPEVGKHILPH 354
A+ + N+L F ++ H
Sbjct: 3724 AIAVINRLGREFECTVNNLYEH 3745
>UniRef50_Q047K7 Cluster: D-alanine-activating enzyme; n=3;
Lactobacillales|Rep: D-alanine-activating enzyme -
Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC
BAA-365)
Length = 500
Score = 61.7 bits (143), Expect = 7e-08
Identities = 66/264 (25%), Positives = 118/264 (44%), Gaps = 17/264 (6%)
Query: 1 MVEILLACTNGASLLIAP-DLTE---VLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKIL 56
++ I A +G L++ P ++TE LF + V W +TPS F +
Sbjct: 195 VMSIYPALLSGGELVVLPHEVTENFAQLFKALPETDVNVWVSTPS--FAQMCFLDRTFDA 252
Query: 57 CARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
++L GE L K ++ LK + +RIF YG TE + + E+ +
Sbjct: 253 DHHASLSHFLFCGEELPR-KEVEMLKKRFPDSRIFNTYGPTEATVAVTQVEITPEILEKY 311
Query: 117 DKEVPLGNCLSETELFVQPHEKNN-TMGKIILASKTRKCILLNRKNGNKE----ENSIKF 171
D+ +P+G +TE+ + + ++ G++I+A + +N +E E+ ++
Sbjct: 312 DR-LPIGYVKEDTEITIDLSQGDDGKSGEMIIAGPSVSKAYINNPEKTEEAFYQEDGVQH 370
Query: 172 IDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLLL 231
TGD+G +FY+GR+ IK G++I L I + Q P VR + P+
Sbjct: 371 YRTGDVGYFDGDLLFYKGRIGFQIKFNGYRIELEEINFYMNQNPLVRHA----VAAPIYK 426
Query: 232 IVYFSAETLSSQELLDFLKCKLDE 255
+ + ++ EL D + K DE
Sbjct: 427 PDHTIKQLVAVVELNDGVSRKFDE 450
>UniRef50_A5W120 Cluster: Amino acid adenylation domain; n=3;
Bacteria|Rep: Amino acid adenylation domain - Pseudomonas
putida F1
Length = 5230
Score = 61.7 bits (143), Expect = 7e-08
Identities = 96/403 (23%), Positives = 166/403 (41%), Gaps = 45/403 (11%)
Query: 3 EILLACTNGASLLIAPDLT----EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCA 58
EI A G L+I P T E + D VT TPS F Q +
Sbjct: 4816 EIFGALLYGGRLVIVPQHTSRSPEAFYQLLADEQVTVLNQTPSAFKQLMA--VATTAEPQ 4873
Query: 59 RS-TLKVLALGGEPLNGIKILKELKHKNNKT-RIFTLYGVTEMSCWASVAEL---DLNKV 113
R L+ + GGE L+ + + ++ ++ +YG+TE + S L DL K
Sbjct: 4874 RPLALRSVVFGGEALDVNSLAPWFERFGDRQPQLVNMYGITETTVHVSYRPLSRADLGKA 4933
Query: 114 TTGDKEVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSIKFID 173
+ P+G + + +V + N I + L + ++ +F+
Sbjct: 4934 ASS----PMGVPIPDLSWYVLDGDLNPVAKGCIGELYVGRAGLARGYLKRSDLSATRFVP 4989
Query: 174 ------------TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSC 220
TGD+ +G + Y GR+D +K G +I L IE+ + P+VR
Sbjct: 4990 DPFGAPGGRLYRTGDLARYHADGVIEYAGRIDHQVKIRGFRIELGEIEARLQAQPQVREA 5049
Query: 221 SCVWLQ--TPLLLIVYF--SAETLSSQ------ELLDFLKCKLDEKYWPDKVIRVDTLPT 270
+ + T L+ Y +AE Q +L + LK L + P ++ +D P
Sbjct: 5050 LVLAQEGATGQQLVAYLIPAAEVALEQQAGLRAQLREQLKEALPDYMVPAHLLLLDRWPL 5109
Query: 271 NAHGKTSKEILVNIYKKSNILQNVENIK-SYLFKELKALVNKDLNYEDL-QSKSFFSLGG 328
A+GK ++ L +++LQ+ S L ++L A+ L E + FF LGG
Sbjct: 5110 TANGKLDRKALPK--ADASLLQHGYRAPGSELEQQLAAIWQDVLKLEQVGLDDHFFELGG 5167
Query: 329 TSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQ 371
S LAV++ +++ L E+G + P L+ + ++ + + Q
Sbjct: 5168 HSLLAVSVVSRVQL---ELGLSLTPQLIFQHPTLASFAEQLAQ 5207
Score = 48.8 bits (111), Expect = 5e-04
Identities = 76/296 (25%), Positives = 118/296 (39%), Gaps = 29/296 (9%)
Query: 63 KVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPL 122
+ L LGGE ++ L +F YG TE + A D +V + VPL
Sbjct: 771 RALVLGGEACPA-GLMAHLAQLAPHCTLFNHYGPTETTVGALA---DAVEVPSATGRVPL 826
Query: 123 GNCLSETELFV-----QPHEKNNTMGKIILASK-------TRKCILLNRKNGNK-EENSI 169
G L+ + +V QP G++ LA R + R N
Sbjct: 827 GRPLANMQAYVLDASLQPLS-TGCQGELYLAGAGVARGYHRRAAMTAERFVPNPFGAAGS 885
Query: 170 KFIDTGDIG-EIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT- 227
+ TGD+ ++ NG V Y GRVD +K G++I L I T+ + PRV V T
Sbjct: 886 RVYRTGDLARQLANGQVDYLGRVDHQVKIRGYRIELGEITDTLKRQPRVHDAVAVIHGTG 945
Query: 228 ---PLLLIVYFSAETLSSQELLD---FLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
++ V ++ +SQ L D L +L + P + + + +P +GK L
Sbjct: 946 SAARIVAYVVPDSQADASQVLADAQAALARQLPDYMLPSRFMALPGMPLTLNGKLDLRAL 1005
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTI 336
Q ++ L ++L + LN + +FF+LGG S LA I
Sbjct: 1006 P--VPDEGPAQAYRAPQTTLQQQLALIWQDVLNVAQVGLDDNFFALGGHSLLATQI 1059
Score = 48.4 bits (110), Expect = 7e-04
Identities = 45/175 (25%), Positives = 81/175 (46%), Gaps = 10/175 (5%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV---WLQTPL 229
TGD+ R +G + Y GRVD +K G +I L IE+ ++ +VR + P
Sbjct: 3473 TGDLARRRADGVLEYVGRVDHQVKIRGFRIELGEIEAALLDSDQVREAVVMAQPGANGPQ 3532
Query: 230 LLIVYFSAETLSS----QELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
L+ + + +++ Q+L LK +L + P + + LP +GK ++ L +
Sbjct: 3533 LVAYCVADDAVAADALKQQLKASLKARLPDYMVPVHWVLMARLPLTPNGKVDRKAL-PLP 3591
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNK 339
S Q +S L ++L A+ L E + +FF LGG S +++ + +
Sbjct: 3592 DMSQARQAYVAPRSELEQQLAAIWQDVLKLEQVGLDDNFFELGGDSIVSIQVVGR 3646
Score = 44.4 bits (100), Expect = 0.012
Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 13/178 (7%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP---- 228
TGD +R +G Y GR+D+ +K G ++ L IE+ ++ C VR V + P
Sbjct: 1947 TGDQVRLRADGQFDYLGRIDNQVKIRGFRVELGEIEACLLACAEVREAVVVAVDGPSGKQ 2006
Query: 229 ----LLLIVYFSAETLSSQ--ELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
L+L +A + Q +L L+ L + P + ++ LP +GK ++ L
Sbjct: 2007 LAAYLVLADSIAAHGPAEQREQLKAALRQSLPDYMLPTHWLVLEQLPLLPNGKLDRKAL- 2065
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNK 339
S + Q ++ L + L AL + L + S +FF LGG S +++ + ++
Sbjct: 2066 PAPDFSALQQAYVAPRNALEQRLAALWQRVLKLPQVGVSDNFFELGGDSIISIQLVSR 2123
>UniRef50_A5FI45 Cluster: Amino acid adenylation domain; n=1;
Flavobacterium johnsoniae UW101|Rep: Amino acid
adenylation domain - Flavobacterium johnsoniae UW101
Length = 1481
Score = 61.7 bits (143), Expect = 7e-08
Identities = 83/335 (24%), Positives = 151/335 (45%), Gaps = 40/335 (11%)
Query: 30 DNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTR 89
D T Q TPS F N K +LK+L GG+ L+ + L E + N
Sbjct: 684 DLKPTIIQATPSFFQMLYNAGWKGN-----KSLKILC-GGDLLS--ETLSEKLRQTNGA- 734
Query: 90 IFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKI 145
++ +YG TE + W+S + ++ +G ++ T+L++ + G I
Sbjct: 735 LWNMYGPTETTIWSSC-----KNIMQANEASNIGKPINNTQLYILDSYMKLLPIGSAGAI 789
Query: 146 ILASK-TRKCILLNRKNGNKE------ENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKR 197
+ + N + N++ + + K +TGD+G NG + + GR D+ +K
Sbjct: 790 YIGGDGLAQGYFKNEELTNEKFVQSPFDQNQKIYNTGDLGRWNENGEIEFMGRNDNQVKI 849
Query: 198 FGHKINLHSIESTVMQCPRVRSCSCVWLQTP---LLLIVY--FSAETLSSQELLDFLKCK 252
G++I L IE+ + Q V++ V ++ LLI Y F E + +++ L+ +
Sbjct: 850 RGYRIELGEIEARLNQIKNVKASVVVAQKSKEQESLLIAYLIFENEEFNPSFIVNILREE 909
Query: 253 LDEKYWPDKVIRVDTLPTNAHGKTSKEIL----VNIYKK--SNILQNVENIKSYLFKELK 306
L E P +++VD P + K ++ L + I K SN + V I+ L+K
Sbjct: 910 LPEYMIPHAIMQVDEFPLTPNKKIDRKELSLRKITIAKSEVSNEMP-VTAIEKSLYKFYT 968
Query: 307 ALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLS 341
++ ++ E + +FF+LGG S AV + N ++
Sbjct: 969 EVL--EIKAEISITDNFFALGGHSLNAVKLINLIN 1001
>UniRef50_A4D936 Cluster: CrpD; n=2; Nostocaceae|Rep: CrpD - Nostoc
sp. ATCC 53789
Length = 3343
Score = 61.7 bits (143), Expect = 7e-08
Identities = 49/195 (25%), Positives = 93/195 (47%), Gaps = 19/195 (9%)
Query: 163 NKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
+K+ + + TGD+ + +G + + GR+D +K G +I L IE+ + P+++
Sbjct: 908 SKKAQAERLFRTGDLARWLPDGNIEFVGRIDHQVKVRGFRIELGEIEAVLSTHPQIQQVV 967
Query: 222 CVWLQT-----PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
+ ++ L+ + E+LS+ L +FLK KL E P + +DTLP GK
Sbjct: 968 VIAIEDIPGSKRLVAYIVCEDESLSTYHLREFLKQKLPEYMMPSAFVILDTLPLTPSGKI 1027
Query: 277 SKEILV----NIYKKSNIL---QNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGT 329
++ L I ++ + + E I + +F + + N ++ +FF LGG
Sbjct: 1028 DRKALPAPDGEISREHEYVPPRTSGEEIIANIFASILGVQNVGIH------DNFFELGGH 1081
Query: 330 SFLAVTICNKLSLTF 344
S LA + ++L + F
Sbjct: 1082 SLLATRLISRLRVAF 1096
Score = 38.3 bits (85), Expect = 0.76
Identities = 34/124 (27%), Positives = 57/124 (45%), Gaps = 13/124 (10%)
Query: 171 FIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR-----SCS-CVW 224
+ +TGD+G I++G + GR D I G H IE+ V + V +C CV
Sbjct: 2268 WFNTGDLGFIKDGCLTITGRQKDIIIINGVNYYSHEIEAVVEELGEVEVSYTAACGVCVA 2327
Query: 225 LQTPLLLIVYFSAETLSSQELLDFLKCKLDE--KYW---PDKVIRVD--TLPTNAHGKTS 277
L+++F+ +LL+ LK ++ KY P +I +D +P + GK
Sbjct: 2328 SNNTEELVIFFTPYVSEKNQLLELLKKVREQVIKYCGINPSYLIPIDKELIPKTSIGKIQ 2387
Query: 278 KEIL 281
+ +L
Sbjct: 2388 RSLL 2391
Score = 35.5 bits (78), Expect = 5.4
Identities = 27/118 (22%), Positives = 60/118 (50%), Gaps = 6/118 (5%)
Query: 231 LIVYFSAETLSSQELLDFLKCKLDEKYW-PDKV--IRVDTLPTNAHGKTSKEILVNIYKK 287
L YF++ T L + +L +++ P+++ ++++ +P G+ ++E + IY
Sbjct: 2910 LTAYFTSPT-PELAALSLQELQLHDRFGIPNQINFVQLEQIPLTQRGEINREQIAAIYGG 2968
Query: 288 SNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
N + + ++ ++L + + LN + +FFSLGG S LAV + +++ F
Sbjct: 2969 LNTSEQTKP-RNQTERQLVEIFQEVLNLPSIGIHDNFFSLGGHSLLAVRLMSEIQQQF 3025
>UniRef50_A0V6U3 Cluster: Amino acid adenylation domain; n=1; Delftia
acidovorans SPH-1|Rep: Amino acid adenylation domain -
Delftia acidovorans SPH-1
Length = 4560
Score = 61.7 bits (143), Expect = 7e-08
Identities = 79/327 (24%), Positives = 136/327 (41%), Gaps = 29/327 (8%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELD--LNKVTTGDKE 119
L+ + +GGE + G + R+ YG TE + AS+ + + ++
Sbjct: 2435 LRQVHVGGEAMPGAGLQAWRDAGLGHVRLLNAYGPTEATVTASLFDCTGLVEGAGAAPQD 2494
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE--------N 167
+P+G L+ ++V G++ + LNR + E +
Sbjct: 2495 LPIGRPLAGRHMWVVDDRMRPVPLGVAGELCIGGPLLSRGYLNRAGLSAERFVADPFGHD 2554
Query: 168 SIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+ G + Y GRVD +K G +I L +++ ++ VR V +
Sbjct: 2555 GARLYRTGDLVRWNAQGQLEYLGRVDHQVKIRGLRIELGEVQAQLLALDDVREAVVVAGE 2614
Query: 227 TPL--LLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
P L+ Y SA TL QE+ + L L + P ++ +D LP NA+GK ++ L
Sbjct: 2615 GPAGTRLLAYVSARSGRTLDEQEMRERLATVLPDYMVPGAIMVLDQLPQNANGKLDRQAL 2674
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ Q E L + A V L E + +S +FF+LGG S L + I ++L
Sbjct: 2675 -PAFGMPAASQAPEGELETLLARIWAEV---LGLERVGRSDNFFALGGDSILGLQIVSRL 2730
Query: 341 SLTFPEVGKHILPHLLSHNKSIGDVLK 367
G + P L +SI ++ +
Sbjct: 2731 R----RFGWKLSPRQLFERQSIAELAR 2753
Score = 56.0 bits (129), Expect = 4e-06
Identities = 50/174 (28%), Positives = 87/174 (50%), Gaps = 9/174 (5%)
Query: 174 TGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP--LL 230
TGD+ + G + Y GR+D +K G +I L IE+ ++ P+VR V + P +
Sbjct: 377 TGDLVRWNDEGQLEYLGRLDHQVKIRGFRIELGEIEARLLAQPQVRESVVVARKGPAGMH 436
Query: 231 LIVYFSA---ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK 287
L Y SA + +++ EL + L +L + P ++ +D LP NA+GK + L
Sbjct: 437 LAAYVSAHEGQQVTAAELRERLALELPDYMVPASIMVLDRLPLNANGKVDRAALPEPELL 496
Query: 288 SNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+++ + E + L AL ++ L E + + FF LGG S LA+ + ++
Sbjct: 497 ASL--HYEAPVGDGEQRLAALWSEVLGVERVGRQDHFFELGGHSLLALKLLERM 548
Score = 41.5 bits (93), Expect = 0.081
Identities = 44/177 (24%), Positives = 81/177 (45%), Gaps = 13/177 (7%)
Query: 174 TGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP---- 228
TGD+ G + Y GR+D +K G +I L IE+ ++ P VR V Q
Sbjct: 1462 TGDLVRWNGEGQIEYLGRLDHQVKIRGLRIELGEIEAHLLAQPGVREAVVVAAQATSGAA 1521
Query: 229 -LLLIVYFS---AETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
L+ Y + A+ ++ L L +L + P ++ + L NA+GK ++ L
Sbjct: 1522 GARLVAYVAGPDADAGLAETLRQALAGRLPDYMQPSAIVVLPALALNANGKVDRKALP-- 1579
Query: 285 YKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + E + + ++L A+ + L + + + +FF LGG S LA+ + ++
Sbjct: 1580 -QPEWAQRGYEPPHNGVEQQLSAIWAELLGQDRVGRRDNFFELGGHSLLAMGMLERM 1635
Score = 35.1 bits (77), Expect = 7.1
Identities = 44/177 (24%), Positives = 78/177 (44%), Gaps = 13/177 (7%)
Query: 174 TGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ--TPLL 230
TGD + E+ +G + Y GR D +K G +I L +E V P V + + T
Sbjct: 4070 TGDLVREMPDGNIEYIGRADHQVKIRGFRIELGEVEKAVRAVPGVVDAAVLVQDAGTGKQ 4129
Query: 231 LIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTL-----PTNAHGKTSKEILVNI 284
L+ Y E ++Q L+ ++ + E + PD ++ TL P GK + L
Sbjct: 4130 LVAYVVGEEGTAAQTLVQRIRQQTGE-HLPDYMLPAHTLVLPALPRLVSGKLDRGALPLP 4188
Query: 285 YKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + + S + L + + L E + ++ +FF LGG S L++ + K+
Sbjct: 4189 QADAGRVHVPPSTASAM--ALARIWQEVLGVERVGETDNFFELGGDSLLSLRMHAKV 4243
>UniRef50_Q08787 Cluster: Surfactin synthetase subunit 3; n=9;
Bacillus|Rep: Surfactin synthetase subunit 3 - Bacillus
subtilis
Length = 1274
Score = 61.7 bits (143), Expect = 7e-08
Identities = 66/291 (22%), Positives = 128/291 (43%), Gaps = 21/291 (7%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ + GGE + + K L+ ++ YG TE + +A+ + + + +P
Sbjct: 722 LRCILFGGERASVPHVRKALRIMG-PGKLINCYGPTEGTVFATAHVV--HDLPDSISSLP 778
Query: 122 LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---ENSIK---- 170
+G +S +++ + +G++ ++ +NR + KE EN K
Sbjct: 779 IGKPISNASVYILNEQSQLQPFGAVGELCISGMGVSKGYVNRADLTKEKFIENPFKPGET 838
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV---WLQ 226
TGD+ + +GT+ Y GR+DD +K GH+I L IE + + P V+ V
Sbjct: 839 LYRTGDLARWLPDGTIEYAGRIDDQVKIRGHRIELEEIEKQLQEYPGVKDAVVVADRHES 898
Query: 227 TPLLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
+ Y T LS++++ LK +L P +D LP +GK +K +L
Sbjct: 899 GDASINAYLVNRTQLSAEDVKAHLKKQLPAYMVPQTFTFLDELPLTTNGKVNKRLLPK-P 957
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVT 335
+ + + ++ + + + + ++ L + + FF+LGG S A+T
Sbjct: 958 DQDQLAEEWIGPRNEMEETIAQIWSEVLGRKQIGIHDDFFALGGHSLKAMT 1008
>UniRef50_P45745 Cluster: Dimodular nonribosomal peptide synthetase;
n=25; Bacillus|Rep: Dimodular nonribosomal peptide
synthetase - Bacillus subtilis
Length = 2378
Score = 61.7 bits (143), Expect = 7e-08
Identities = 76/333 (22%), Positives = 136/333 (40%), Gaps = 33/333 (9%)
Query: 33 VTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKEL--KHKNNKTRI 90
VT TPS F+Q + L +L+ + GGE L + L++ +H N+ ++
Sbjct: 1757 VTVLNQTPSAFYQFMQAEREQPDLGQALSLRYVIFGGEALE-LSRLEDWYNRHPENRPQL 1815
Query: 91 FTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKII 146
+YG+TE + S ELD + + +G + + ++V G++
Sbjct: 1816 INMYGITETTVHVSYIELDRSMAALRANSL-IGCGIPDLGVYVLDERLQPVPPGVAGELY 1874
Query: 147 LASKTRKCILLNRKNGNKEE--------NSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKR 197
++ L R E + TGD+ +R +G++ Y GR D +K
Sbjct: 1875 VSGAGLARGYLGRPGLTSERFIADPFGPPGTRMYRTGDVARLRADGSLDYVGRADHQVKI 1934
Query: 198 FGHKINLHSIESTVMQCPRVRSCSCVWLQTP-----LLLIVYFSAETLSSQELLDFLKCK 252
G +I L IE+ ++Q P++ + + + L V S ET + EL + +
Sbjct: 1935 RGFRIELGEIEAALVQHPQLEDAAVIVREDQPGDKRLAAYVIPSEETFDTAELRRYAAER 1994
Query: 253 LDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQN-----VENIKSYLFKELKA 307
L + P + + LP +GK ++ L + + E I LF E+
Sbjct: 1995 LPDYMVPAAFVTMKELPLTPNGKLDRKALPAPDFAAAVTGRGPRTPQEEILCDLFMEVLH 2054
Query: 308 LVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKL 340
L ++ FF LGG S LAV + +++
Sbjct: 2055 LPRVGID------DRFFDLGGHSLLAVQLMSRI 2081
Score = 52.8 bits (121), Expect = 3e-05
Identities = 87/366 (23%), Positives = 155/366 (42%), Gaps = 47/366 (12%)
Query: 2 VEILLACTNGASLLIAPDLT----EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC 57
+E+ L +GA ++IA T + L + + Q TP+ + H+ + + L
Sbjct: 661 LELYLPLISGAQIVIAKKETIREPQALAQMIENFDINIMQATPTLW--HALVTSEPEKLR 718
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
L+VL +GGE L +L+EL+ + + LYG TE + W++ A L+ G
Sbjct: 719 G---LRVL-VGGEALPS-GLLQELQDLH--CSVTNLYGPTETTIWSAAAFLE-----EGL 766
Query: 118 KEVP-LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE------ 166
K VP +G + T+++V + +G++ +A +R + E
Sbjct: 767 KGVPPIGKPIWNTQVYVLDNGLQPVPPGVVGELYIAGTGLARGYFHRPDLTAERFVADPY 826
Query: 167 --NSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
+ TGD R +G++ Y GR D IK G +I L I++ + P + + V
Sbjct: 827 GPPGTRMYRTGDQARWRADGSLDYIGRADHQIKIRGFRIELGEIDAVLANHPHIEQAAVV 886
Query: 224 WLQTP---LLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
+ L Y A+ + + EL ++ L + P + +D LP +GK ++
Sbjct: 887 VREDQPGDKRLAAYVVADAAIDTAELRRYMGASLPDYMVPSAFVEMDELPLTPNGKLDRK 946
Query: 280 ILVNIYKKSNILQNV-----ENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAV 334
L +++ E I LF E+ L ++ SFF LGG S LA
Sbjct: 947 ALPAPDFSTSVSDRAPRTPQEEILCDLFAEVLGLARVGID------DSFFELGGHSLLAA 1000
Query: 335 TICNKL 340
+ +++
Sbjct: 1001 RLMSRI 1006
>UniRef50_UPI0000E46FCE Cluster: PREDICTED: similar to RIKEN cDNA
A230062G08; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to RIKEN cDNA A230062G08 -
Strongylocentrotus purpuratus
Length = 348
Score = 61.3 bits (142), Expect = 9e-08
Identities = 36/112 (32%), Positives = 58/112 (51%), Gaps = 4/112 (3%)
Query: 1 MVEILLACTNGASLLIAPDLTEV----LFHEDNDNSVTFWQTTPSKFFQHSNENIKNKIL 56
+VE+ + + GA+LL+ P ++ L N VT Q TPS + S+ ++ +L
Sbjct: 225 VVEMFMTWSQGATLLMVPAKLKMAPSSLAQVLKRNHVTVLQATPSLVSRFSSSALQQDLL 284
Query: 57 CARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAEL 108
A STL++L GGE + + N+T LYG+TE+S WAS ++
Sbjct: 285 GASSTLRLLVFGGESCPTPATIARWRGAGNRTEFINLYGITEVSSWASCFQI 336
>UniRef50_Q8YWG6 Cluster: Peptide synthetase; n=3; Nostocaceae|Rep:
Peptide synthetase - Anabaena sp. (strain PCC 7120)
Length = 987
Score = 61.3 bits (142), Expect = 9e-08
Identities = 66/244 (27%), Positives = 111/244 (45%), Gaps = 29/244 (11%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWAS---VAELDLNKVTTGDK 118
L+ L GE L I + + KT + LYG TE S + + E ++TT
Sbjct: 287 LRWLMFSGEALPMSFIQRWIDRHGLKTGLANLYGPTEASIDVTCHLITERPDERLTT--- 343
Query: 119 EVPLGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSI---K 170
++P+G + + V QP + N MG++ L + L K+ K +
Sbjct: 344 QIPIGKAIDNVYVKVLDGGMQPVQPGN-MGELWLGGV--QLALGYLKDPEKTAQAFCPNP 400
Query: 171 FID--------TGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
F D TGD + E+ +GT+ Y GR+D +K G +I L IES + P VR +
Sbjct: 401 FTDIPGDYIYRTGDLVKELPDGTIEYHGRIDHQVKIRGFRIELGEIESVLTTHPDVREAA 460
Query: 222 CV---WLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
+ + + L+ S + ++ L ++L+ KL P + + +D+LP N +GK +
Sbjct: 461 ALAVDYGEGQKRLVACISGNKIKNRFLKEYLEQKLPHYMIPQRFLWLDSLPKNHNGKLDR 520
Query: 279 EILV 282
+ LV
Sbjct: 521 KALV 524
>UniRef50_Q8PKR7 Cluster: ATP-dependent serine activating enzyme;
n=1; Xanthomonas axonopodis pv. citri|Rep: ATP-dependent
serine activating enzyme - Xanthomonas axonopodis pv.
citri
Length = 2008
Score = 61.3 bits (142), Expect = 9e-08
Identities = 55/196 (28%), Positives = 89/196 (45%), Gaps = 7/196 (3%)
Query: 152 RKCILLNRKNGNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIEST 210
R+ + R G+ + TGD+ + +G + Y GR D +K G +I L I++
Sbjct: 435 REALTAERFIGDPFYPGARMYRTGDLCRWLDDGRLDYVGRNDAQVKIRGRRIELGEIQAH 494
Query: 211 VMQCPRVRSCSC-----VWLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRV 265
++ P+VR V + L+ V +AE ++ EL L+ L E P+ + V
Sbjct: 495 LLAHPQVREAVVLAREDVAGERRLVGYVIATAEAPTAAELQRHLRVHLPEYLVPEAFVPV 554
Query: 266 DTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFF 324
D P A+GK + L LQ E + L ++L + L E + + +FF
Sbjct: 555 DAWPLTANGKLDRHALPGPDAAQRNLQTYEPPANALEQQLAEIWQAVLGVERVGRHDNFF 614
Query: 325 SLGGTSFLAVTICNKL 340
LGG S LAVT+ +L
Sbjct: 615 QLGGHSLLAVTLVERL 630
Score = 40.7 bits (91), Expect = 0.14
Identities = 63/308 (20%), Positives = 129/308 (41%), Gaps = 35/308 (11%)
Query: 55 ILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVT 114
+L A + L+ L +GG+ L+ + + L + R+ YG TE + +A++ + +T
Sbjct: 1403 LLPAIAQLRYLIVGGDVLDPAVVARVLA-EGAPQRLLNGYGPTETTTFATI-----HCIT 1456
Query: 115 TGDKEVPLGNCLSETELFV-QPHEK---------------NNTMGKIILASKTRKCILLN 158
+P+G + T ++V H +G + + T + + +
Sbjct: 1457 EVSGPIPIGRPIGNTRVYVLDAHGTPLPIGVAGELYIGGDGVALGYLHQPTLTAERFIAD 1516
Query: 159 RKNGNKEENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV 217
R +G + + +GD+ R +G + Y GR D +K G ++ L I S + P V
Sbjct: 1517 RFSGKADARLYR---SGDLVRWRADGVLEYLGRTDGQVKVCGFRVELGEIASALQTHPAV 1573
Query: 218 RSCSCVW---LQTPLLLIVYFSAETLS-----SQELLDFLKCKLDEKYWPDKVIRVDTLP 269
+ V ++ L+ Y+ + + +Q L L ++ + P ++++ LP
Sbjct: 1574 AIAAVVQREDVRGSKQLVAYYQVDVAANLAHDAQALRMHLLTRVPDYMLPSAYVQMEQLP 1633
Query: 270 TNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGG 328
A+GK + L + + + + L L L ++ L + + + F +LGG
Sbjct: 1634 LTANGKLDRHALPLPARNDHAGHDDTPPQGELETLLHTLWSQLLRIDRIGRHDDFLALGG 1693
Query: 329 TSFLAVTI 336
S L V +
Sbjct: 1694 HSLLLVRL 1701
>UniRef50_Q333V2 Cluster: NRPS protein; n=1; Micromonospora sp.
ML1|Rep: NRPS protein - Micromonospora sp. ML1
Length = 768
Score = 61.3 bits (142), Expect = 9e-08
Identities = 67/294 (22%), Positives = 128/294 (43%), Gaps = 33/294 (11%)
Query: 12 ASLLIAPD-LTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGE 70
A+ L PD L ++L E+ +T W + P+ ++ + R TL+++ L G+
Sbjct: 484 AAELAEPDTLVDLLEQEE----ITIWDSAPAALAMVM-PFVQVREPAGRGTLRLVLLSGD 538
Query: 71 PLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETE 130
+ + + +++ + L G TE + W++ + V G +P G +
Sbjct: 539 WIP-VPLPDQIRAAFPNAEVVALGGATECTVWSN--HYRVGDVDPGWPSIPYGKPMQNAR 595
Query: 131 LFVQPHE----KNNTMGKIILASKTRKCILLN--RKNGNKEENSI----------KFIDT 174
+V H N G + +A + C+ L R G + + T
Sbjct: 596 YYVLDHGLGPCPNGAEGDLYIAGE---CVALGYARSPGLTAAKFLPDPWAHRTGERMYHT 652
Query: 175 GDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP--LLL 231
GD + +G + + GR+DD +K G++I L ++S ++QC VR+ S V P L
Sbjct: 653 GDRARWLPSGDLEFLGRLDDQVKVRGYRIELGEVQSALLQCAGVRAASVVAPSGPGGRTL 712
Query: 232 IVYF--SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
++ +AE L + E++ L+ L P +++ +D LP GK + L++
Sbjct: 713 AAFYVPTAEPLPTAEVVGALQRILPSYMVPTRIVALDELPLTNTGKVDRAALLS 766
>UniRef50_Q20CI8 Cluster: CesB; n=7; cellular organisms|Rep: CesB -
Bacillus cereus
Length = 2681
Score = 61.3 bits (142), Expect = 9e-08
Identities = 81/362 (22%), Positives = 150/362 (41%), Gaps = 38/362 (10%)
Query: 3 EILLACTNGASLLIAPDLT----EVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCA 58
EI A NG +L + D E L E N T + F Q +++N
Sbjct: 2025 EIWGALLNGLTLHLVEDYVILDGEALQEEIQQNKATIMWVSAPLFNQLADQNP-----AM 2079
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
+ +K L +GG+ L+ I K + H I YG TE + +++ +D
Sbjct: 2080 FTGIKQLLIGGDVLSPKHINKVMDHCA-PINIINGYGPTENTTFSTSFVID----QMYQD 2134
Query: 119 EVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE-------N 167
+P+G ++ + ++ +N +G++ + +N + +E
Sbjct: 2135 SIPIGTPIANSSAYILDVHQNIQPIGVVGELCVGGDGVAKGYVNLEQLTEERFIADPFLK 2194
Query: 168 SIKFIDTGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
TGD + + NG + Y GRVD+ +K G +I L +I +T+ QC ++ V +
Sbjct: 2195 GSTMYRTGDYVKLLPNGNIQYIGRVDNQVKIRGFRIELEAIMNTLKQCESIKDVIVVVQE 2254
Query: 227 T---PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L+ E+LS + + + K L E P + I ++ +P + +GK L
Sbjct: 2255 QNGYKTLVAYVVGEESLSIETVRAYAKKHLAEYMVPSQFIFIEEIPLSINGKVQYSKLPK 2314
Query: 284 I----YKKSNILQNVENIKSYLFKELKALVNK-DLNYEDLQSKSFFSLGGTSFLAVTICN 338
+ +KK L ++ + + + ++ K D D SFF+ GG S L++ + +
Sbjct: 2315 VQEVLHKKVETLLPENRLEEIILRVYRDVLEKEDFGVTD----SFFAYGGDSLLSIQVVS 2370
Query: 339 KL 340
L
Sbjct: 2371 ML 2372
>UniRef50_Q1RS70 Cluster: Hybrid NRPS/PKS; n=4; cellular
organisms|Rep: Hybrid NRPS/PKS - Bacillus
amyloliquefaciens
Length = 5433
Score = 61.3 bits (142), Expect = 9e-08
Identities = 66/274 (24%), Positives = 118/274 (43%), Gaps = 27/274 (9%)
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHE----KNNTMGK 144
RI +YG TE S +A+ ++T+ + P+G + T L++ + + G+
Sbjct: 777 RIENIYGPTETSIYAAYYSCGQKEITS--RNTPIGKPIHNTRLYIVDEKLSPVPDGVAGE 834
Query: 145 IILASKTRKCILLNRKN-------GNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIK 196
+ +A N+ N K TGD+ + +G + Y GR+D +K
Sbjct: 835 LCVAGAGLARGYYNQPELTAASFIDNPFSEGEKLYKTGDLARWLPDGNIEYAGRIDSQVK 894
Query: 197 RFGHKINLHSIESTVMQCPRVRSCSCVWLQT--PLLLIVYFSA---ETLSSQELLDFLKC 251
G +I L +IE+ + + P + + V + LI Y++A T + L + L
Sbjct: 895 IRGFRIELGAIETKLSEHPDILDQAVVVQEKNGHKKLIAYYTARSGHTADEKALRNHLLS 954
Query: 252 KLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVN- 310
L + P IR+D LP GK +++ ++ ++ I+ E E +A V
Sbjct: 955 SLPDYMAPAHFIRLDALPLTPSGKVNRK---DLKQRKVIVHRSEKTGRLPLSEAEAKVTA 1011
Query: 311 --KD-LNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
+D LN ++ FF +GG S LAV ++
Sbjct: 1012 IWEDLLNTAGIKIEDGFFDVGGDSLLAVAAAERI 1045
>UniRef50_A3WXS1 Cluster: Probable non-ribosomal peptide synthetase;
n=2; Bradyrhizobiaceae|Rep: Probable non-ribosomal
peptide synthetase - Nitrobacter sp. Nb-311A
Length = 3272
Score = 61.3 bits (142), Expect = 9e-08
Identities = 56/198 (28%), Positives = 95/198 (47%), Gaps = 9/198 (4%)
Query: 167 NSIKFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
N + TGD+ R+ G + Y GR D +K G +I L IE+ +++ VR+ + V
Sbjct: 3046 NGDRLYRTGDLARWRDDGVIDYVGRADQQVKIRGFRIELGEIEACLIEQRGVRAAAVVAQ 3105
Query: 226 --QTPLLLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
+T L+ Y S + TL L D L L + P ++ ++ LP + +GK ++ L
Sbjct: 3106 DSKTGRHLVAYASGDPTLDGAALRDALAAVLPDYMVPATIVVLEQLPLSRNGKIDRKALP 3165
Query: 283 NIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLS 341
++ + E + + L + ++ L+ E + ++ FF LGG S LAV + LS
Sbjct: 3166 KPHEGMLACRRYEAPEDDVEIALARMWSEILDVERIGRNDHFFELGGHSLLAVRV---LS 3222
Query: 342 LTFPEVGKHI-LPHLLSH 358
L E G I + L +H
Sbjct: 3223 LVSQEFGVSIPISDLFAH 3240
>UniRef50_Q2SW14 Cluster: Peptide synthetase, putative; n=1;
Burkholderia thailandensis E264|Rep: Peptide synthetase,
putative - Burkholderia thailandensis (strain E264 / ATCC
700388 / DSM 13276 /CIP 106301)
Length = 3650
Score = 60.9 bits (141), Expect = 1e-07
Identities = 79/306 (25%), Positives = 131/306 (42%), Gaps = 26/306 (8%)
Query: 56 LCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTT 115
L A +L+ + +G EPL K L L+ + + YG TE + + S + LD+
Sbjct: 777 LVASLSLRRILVGVEPLRE-KDLYRLERLLPELIVVNGYGPTETTVF-STSYLDMRDY-- 832
Query: 116 GDKEVPLGNCLSETELFV-QPHEKN---NTMGKIILASKTRKCILLNRKNGNKEE----- 166
D+ P+G ++ T +++ H + G+I +A LNR E
Sbjct: 833 -DRAAPIGRPIANTRIYILDSHGQPVPIGVAGEIHIAGAGVARGYLNRPELTAERFVSDS 891
Query: 167 ----NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
+ + TGD+G + +GT+ Y GR D +K G +I L IE+ + +C VR
Sbjct: 892 FAAAPNARMYRTGDLGRWLPDGTIEYLGRNDFQVKIRGLRIELGEIEARLARCDGVRDAV 951
Query: 222 CVWLQ-TP--LLLIVYF---SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGK 275
+ + TP L+ Y S L EL L +L E P + +D LP +GK
Sbjct: 952 VIAREDTPGDKRLVAYVLPQSGVALVPAELRRQLAGQLAEHMLPSAFVMLDALPLTPNGK 1011
Query: 276 TSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAV 334
++ L + + + + E + L + L E + + FF LGG S L V
Sbjct: 1012 LDRKALPAPDQTAVVSRGYEAPTGEVETALARIWQDLLGLEQVGRHDHFFELGGHSMLVV 1071
Query: 335 TICNKL 340
++ +L
Sbjct: 1072 SMIERL 1077
Score = 56.0 bits (129), Expect = 4e-06
Identities = 51/211 (24%), Positives = 93/211 (44%), Gaps = 14/211 (6%)
Query: 174 TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV-RSCSCV----WLQT 227
TGD + +G + + GRVDD +K G +I + IE+ + P V R + + QT
Sbjct: 1977 TGDRARVLADGNLEFLGRVDDQVKIRGFRIEIGEIEAALGAAPGVERGVATIVEHHGRQT 2036
Query: 228 PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK 287
+V + L E+ D L +L P ++ +D++P +GK + L+ +
Sbjct: 2037 IAAYVVARANAVLDHAEIRDALARRLPPYMLPASIVSIDSVPLTRNGKIDRRALMQVRAP 2096
Query: 288 SNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTFPE 346
++ + N+ + K L ++ L E + ++FF GG S LA+ I + E
Sbjct: 2097 ASPAEGPRNV---VEKALASIWQAVLGREAIDVHENFFDAGGDSMLAIRIVTRAR----E 2149
Query: 347 VGKHILPHLLSHNKSIGDVLKTITQDTNCLE 377
HI+P + ++I + T+ E
Sbjct: 2150 QRIHIMPRDVLQLQTIAKIAAAAGAATDVAE 2180
Score = 41.9 bits (94), Expect = 0.062
Identities = 44/177 (24%), Positives = 72/177 (40%), Gaps = 8/177 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--- 229
+GD+G + G + GR D +K G++I L IE + + +
Sbjct: 3418 SGDLGRFLPGGRMESLGRADRQVKIRGYRIELGEIECALSSLEGIGGAVADVREGASGRQ 3477
Query: 230 LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSN 289
L+ Y +A + +Q + LK +L + P +IRVD A+GK + L +
Sbjct: 3478 LVAWYVAAADMDAQRVRTALKQRLPDSMMPSALIRVDGFALTANGKIDRRALPREAAPTA 3537
Query: 290 ILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTFP 345
Q N L + L A+ + L E + ++FF GG S V +S P
Sbjct: 3538 PAQGPRNA---LEEALAAIWCEVLGREAIGIDENFFDAGGDSLAIVRAHGLMSTRLP 3591
>UniRef50_Q70JX4 Cluster: FenD protein; n=18; Bacillus|Rep: FenD
protein - Bacillus amyloliquefaciens
Length = 3605
Score = 60.9 bits (141), Expect = 1e-07
Identities = 48/174 (27%), Positives = 86/174 (49%), Gaps = 8/174 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL-----QT 227
TGD+ + + +GT+ Y GR+D+ +K G+++ L IES + V+ + QT
Sbjct: 2913 TGDLAKWLPDGTLQYIGRIDEQVKIRGYRVELKEIESALTGIKGVKEAAVTAHTASAGQT 2972
Query: 228 PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK 287
L + + E S+ + L+ ++ P ++ LP +GK + L KK
Sbjct: 2973 ELCAYI-VTEEGTESETVQQALRNEMPAYMVPAFFETLEALPVTPNGKLDRRALPEPRKK 3031
Query: 288 SNILQNVENIKSYLFKELKALVNKDLNYEDLQS-KSFFSLGGTSFLAVTICNKL 340
++ Q +S + KEL A+ ++ L E++ + KSFF LGG S A+ + +L
Sbjct: 3032 AHTGQAFTEPESDMEKELSAIWSEVLGTENIAADKSFFELGGDSIKALQVSARL 3085
Score = 44.8 bits (101), Expect = 0.009
Identities = 66/263 (25%), Positives = 115/263 (43%), Gaps = 24/263 (9%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT----P 228
TGD+ +R +G + Y GR DD +K G++I IE+ + V+ + V +QT
Sbjct: 855 TGDLARLRADGQIEYIGRTDDQVKIRGYRIEPKEIETVLANHHAVKE-AAVLIQTNESGE 913
Query: 229 LLLIVYFS-AETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL--VNIY 285
L Y S ++ +L L +L + P K VD++P A+GK + L + Y
Sbjct: 914 NELCAYCSVSQATDPSQLRSDLAKELPDYMIPVKWAFVDSIPLTANGKVDQRALPEASAY 973
Query: 286 ---KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSL 342
++ +NV +K E + L + + D FF LGG S A + K++
Sbjct: 974 AAGRQYTAPRNVTELKLTRIWE-EVLQSGPIGVHD----HFFELGGHSLKATALVAKIA- 1027
Query: 343 TFPEVGKHI-LPHLLSHNKSIGDVLKTITQ-DTNCLENKFKKSIKRNRSTSSHGENS-IS 399
E I L + SH ++ ++ K I++ + N + K +K SS + +
Sbjct: 1028 --KECSVQIPLSDVFSH-PTVEELAKIISEAEENPFASIEKTEMKETYPVSSAQKRMYVL 1084
Query: 400 YKKGAGGIRNSNTVEFVVQWTFD 422
++ GG+ + V+ FD
Sbjct: 1085 HQLENGGVSYNIPAVLEVKGPFD 1107
>UniRef50_Q2ANX0 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Bacillus weihenstephanensis KBAB4|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Bacillus weihenstephanensis KBAB4
Length = 1476
Score = 60.9 bits (141), Expect = 1e-07
Identities = 79/352 (22%), Positives = 145/352 (41%), Gaps = 36/352 (10%)
Query: 10 NGASLLIAP-DLTE-VLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLAL 67
+G ++I P D E VL+ + + + TPS F + + + C+ +K + +
Sbjct: 644 SGNQIIIYPADANEYVLYRIFKEKKASIIKLTPSHLFLLKDSDF---VGCS---IKKIIV 697
Query: 68 GGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK--EVPLGNC 125
GGE L K +T+I+ YG TE + + D+ K DK VP+G
Sbjct: 698 GGENLTVDLAANIQKKLGRETKIYNEYGPTETVVGCMIHQFDIEK----DKGVSVPIGVP 753
Query: 126 LSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEENSI-------KFIDT 174
+++V + +G+I ++ + N ++ +E + + +
Sbjct: 754 AQNMKIYVLDSDLRPVPMGVVGEIYISGEGVARGYFNNQDLTRERFIVNPYSEKEQMYKS 813
Query: 175 GDIGEIRNGT-VFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV----WLQTPL 229
GD+ G + Y GR DD +K G +I L IE + + P ++ + +
Sbjct: 814 GDLARFIEGDKIEYLGRKDDQVKVRGFRIELKEIEINLQKYPSIKEVVVIDQEDYDGNHY 873
Query: 230 LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSN 289
L Y + + EL FLK L P I + +P +GK +E L K
Sbjct: 874 LCAYYTENAKVKTSELFRFLKEILPVYMIPSYFIVLKEIPLTFNGKLDREALPKPEVKIE 933
Query: 290 ILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKL 340
+ + + +L ++ + LN E + + +F+ LGG S A+ I +K+
Sbjct: 934 -----KKTEGEIESDLLGIIREVLNVEKVSIRDNFYHLGGDSIKAIQISSKI 980
>UniRef50_Q0VZ70 Cluster: Non ribosomal peptide synthase; n=1;
Chondromyces crocatus|Rep: Non ribosomal peptide synthase
- Chondromyces crocatus
Length = 3912
Score = 60.9 bits (141), Expect = 1e-07
Identities = 66/280 (23%), Positives = 120/280 (42%), Gaps = 21/280 (7%)
Query: 89 RIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFV-QPHEKNNTMG---- 143
R YG TE++ A+ E + ++ P+G L TE+++ H + +G
Sbjct: 2762 RFVNAYGPTEITVAATAMECPVTMFQETEQPPPIGCPLQSTEIYILDAHLRPVPVGVPGD 2821
Query: 144 ------KIILASKTRKCILLNR--KNGNKEENSIKFIDTGDIGEIR-NGTVFYRGRVDDT 194
K+ R + R + + + TGDI + +GT+ + GR D+
Sbjct: 2822 LYIGGAKLTRGYIHRPALTAERYIPHPFSDRPGARLYVTGDIARYQLDGTIDFLGRRDNQ 2881
Query: 195 IKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL---LLIVYFSAETL---SSQELLDF 248
+K G++I L +E+ + P VR V + L+ Y++A++ +++ L D
Sbjct: 2882 VKVRGYRIELGEVEAALNDHPGVREAVVVAQKDGAGDNRLVAYWAAKSTPPTTTEALRDA 2941
Query: 249 LKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKAL 308
L +L P +R+D LP NA GK ++ L + + ++ + L A+
Sbjct: 2942 LSKRLAAYMIPSVFVRMDALPLNATGKIDRQGLPPVDDTMLDREQFVAPRTATEETLTAI 3001
Query: 309 VNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKLSLTFPEV 347
+ L + + FF LGG S LA+ I ++ F V
Sbjct: 3002 WSSTLGVARVGIRDDFFKLGGHSLLALNITTQIQKRFGHV 3041
Score = 35.5 bits (78), Expect = 5.4
Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP 228
TGD+ + +G + + GRVD+ +K G +I L IES + P V + + + P
Sbjct: 862 TGDLARYLPDGNLVFLGRVDNQVKLRGLRIELEEIESALKSHPHVGDAAVIVHEAP 917
>UniRef50_Q0LLQ9 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1126
Score = 60.9 bits (141), Expect = 1e-07
Identities = 71/306 (23%), Positives = 129/306 (42%), Gaps = 24/306 (7%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
++++L G + G + + + TR+ YGVTE ++ E ++V
Sbjct: 778 SMRLLIAGSDTWYGEEYARVARLCGPDTRLVNSYGVTEAVIDSTYFEAGAAAELPARRQV 837
Query: 121 PLGNCLSETELFV-----QPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSI------ 169
P+G + T +V QP + G++ L +R + R+ G E +
Sbjct: 838 PIGRPFAATRAYVLNRLGQP-QPIGVPGELYLGG-SRLALGYWRRPGLTAERFVPDPFAG 895
Query: 170 ----KFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW 224
+ TGD R +GT+ + GR+D +K G +I L IE+ ++Q P V +
Sbjct: 896 EPGARMYRTGDAARFRADGTIEFLGRIDQQVKLHGVRIELGEIEAILLQQPGVIQAAAAI 955
Query: 225 LQTPL---LLIVYFSAETLSSQELL-DFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
+ L +L+ Y + L + L L+ +L E P I + +LP +GK ++
Sbjct: 956 RENQLGHPILVAYLVTDALGDEAALRAALRERLPEHMVPAATIILPSLPLTPNGKIDRQA 1015
Query: 281 LVN-IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICN 338
L +S + E S + + L + + L E + + +FF LGG S L +
Sbjct: 1016 LPEPDLGRSEMSAAYEAPGSLIEETLAEIWGEVLKREQVGIRDNFFELGGHSLLITQVIY 1075
Query: 339 KLSLTF 344
+ + F
Sbjct: 1076 RANEAF 1081
>UniRef50_Q9RTJ3 Cluster: Serine/threonine protein kinase-related
protein; n=2; Deinococcus|Rep: Serine/threonine protein
kinase-related protein - Deinococcus radiodurans
Length = 574
Score = 60.5 bits (140), Expect = 2e-07
Identities = 50/201 (24%), Positives = 92/201 (45%), Gaps = 15/201 (7%)
Query: 555 DQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIF 614
D + A L + ++ T G L + +T+ W + P+F+ P + D + F
Sbjct: 142 DGDVFASPALRPDGSVVVATAGGTVYALSSSGQTL-WSYKVGAPVFSSPAVAA-DGTIYF 199
Query: 615 AEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITN 674
NG +H + E G WTY A+ ++FSS + + +YFG D ++YS++
Sbjct: 200 GAQNGRLHALSPE-GRLTWTY-AARSSVFSSPALDA----EGNLYFGSGDRSIYSLSPAG 253
Query: 675 FQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDGKLWVIHSELGTVTAQYQLPGETFSSP 734
+L W V ++P + L++ S DG+L+ +++ G V Y G ++P
Sbjct: 254 ---TLRWVQPTGLFVNASPIVTRAGLVVVGSYDGQLYALNTN-GQVAWTY-AAGAAIAAP 308
Query: 735 I--ICDDHVFIGCRNDLLYSL 753
+ D V +G N L+++
Sbjct: 309 AAELSDGSVVVGDLNGTLHAV 329
Score = 41.9 bits (94), Expect = 0.062
Identities = 36/128 (28%), Positives = 61/128 (47%), Gaps = 11/128 (8%)
Query: 417 VQWTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPIL 476
++W TG V+ASP + ++ V+ VGS+ G++ +N N G + + I AP
Sbjct: 255 LRWVQPTGLFVNASPIVTRAGLVV---VGSYDGQLYALNTN-GQVAWTYAAGAAIAAPAA 310
Query: 477 CVHDECVTSPCGVVGTYDGTVICFLLENCSVIWQINVGSMIKSKATYC-KGVLYIASYDG 535
+ D V VVG +GT+ + +W + G+ I + A +G LY A G
Sbjct: 311 ELSDGSV-----VVGDLNGTLHA-VTPTGQALWTLPGGAKIDTGAAVSDQGTLYFAVDGG 364
Query: 536 NIRCIDIL 543
N+ ++ L
Sbjct: 365 NLNAVENL 372
Score = 40.7 bits (91), Expect = 0.14
Identities = 42/168 (25%), Positives = 76/168 (45%), Gaps = 16/168 (9%)
Query: 589 IIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCV 648
+ W+ L G +FA P L D V+ A G ++ + G +W+Y +FSS V
Sbjct: 135 LTWKAKLDGDVFASPALRP-DGSVVVATAGGTVYALS-SSGQTLWSYK-VGAPVFSSPAV 191
Query: 649 KEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFNDKLILAASTDG 708
+YFG + +++++ + L W S V+S+P + + + S D
Sbjct: 192 AA----DGTIYFGAQNGRLHALSP---EGRLTWTYAARSSVFSSPALDAEGNLYFGSGDR 244
Query: 709 KLWVIHSELGTVTAQYQLPGETF--SSPIIC-DDHVFIGCRNDLLYSL 753
++ + S GT+ ++ P F +SPI+ V +G + LY+L
Sbjct: 245 SIYSL-SPAGTL--RWVQPTGLFVNASPIVTRAGLVVVGSYDGQLYAL 289
Score = 37.9 bits (84), Expect = 1.0
Identities = 40/175 (22%), Positives = 74/175 (42%), Gaps = 10/175 (5%)
Query: 515 SMIKSKATYCKGVLYIASYDGNIRCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGT 574
S+ S A +G LY S D +I + T++ V + ++A ++ + ++ G+
Sbjct: 224 SVFSSPALDAEGNLYFGSGDRSIYSLSP-AGTLR-WVQPTGLFVNASPIVTRAGLVVVGS 281
Query: 575 LSGVCACLHVNTKTIIWQGSLKGPIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWT 634
G L+ N + + W + G A P +D V+ ++NG +H T G +WT
Sbjct: 282 YDGQLYALNTNGQ-VAWTYAA-GAAIAAPAAELSDGSVVVGDLNGTLHAVT-PTGQALWT 338
Query: 635 YNGAKGNIFSSLCVKEINKFKWQMYFGCHDNNVYSVNITNFQPSLHWKTRVSSPV 689
G I + V + + +YF N+ +V + W T +SP+
Sbjct: 339 LPGG-AKIDTGAAVSD----QGTLYFAVDGGNLNAVENLRPLATGPWPTFRASPL 388
>UniRef50_Q8DTJ6 Cluster: Putative gramicidin S synthetase; n=1;
Streptococcus mutans|Rep: Putative gramicidin S
synthetase - Streptococcus mutans
Length = 1229
Score = 60.5 bits (140), Expect = 2e-07
Identities = 46/181 (25%), Positives = 85/181 (46%), Gaps = 5/181 (2%)
Query: 169 IKFIDTGDI-GEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV-WLQ 226
I+ +TGD+ ++ N Y R D +K G+++ L +E+T++ V + +LQ
Sbjct: 600 IRMYNTGDVVRQLGNSKYEYLRRTDKQLKIRGYRVELQEVENTILNIDGVDLAQVIPFLQ 659
Query: 227 TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
+++ F + +LS +L + L L P V + +P N +GK + L+ Y+
Sbjct: 660 NKNTIMLAFYSGSLSENDLKEKLSKILPNYMIPSIVKKYTQMPLNRNGKIDSQELLLRYQ 719
Query: 287 KS--NILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKLSLT 343
S N + + +++ + L ++ + SFF LGG S A+ IC +LS
Sbjct: 720 DSLRNTTISSPTFSDKMMEKIYNVWKAVLGEHNIGTDISFFELGGNSINAMLICTQLSRE 779
Query: 344 F 344
F
Sbjct: 780 F 780
>UniRef50_Q7N5R5 Cluster: Similar to antibiotic synthetase; n=1;
Photorhabdus luminescens subsp. laumondii|Rep: Similar to
antibiotic synthetase - Photorhabdus luminescens subsp.
laumondii
Length = 1065
Score = 60.5 bits (140), Expect = 2e-07
Identities = 85/368 (23%), Positives = 149/368 (40%), Gaps = 37/368 (10%)
Query: 7 ACTNGASLLIAP--------DLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCA 58
A NG L+I P D ++L E VT TPS F + + + L
Sbjct: 670 ALLNGGRLVIVPWEVSRSPTDFLQLLVSE----KVTVLNQTPSAFQALIHADREAPELGQ 725
Query: 59 RSTLKVLALGGEPLNGIKILKEL--KHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
L+ + GGE LN IL+E +H +N ++ +YG+TE + + L V
Sbjct: 726 SLVLRTVIFGGEALNA-HILEEWYQRHDDNAPQLVNMYGITETTVHVTYFPLSREVVAQP 784
Query: 117 DKEVPLGNCLSETELFVQPHEKNNT----MGKIILASKTRKCILLNRKNGNKEE------ 166
+ +G + + +++ ++ +G+I + LNR E
Sbjct: 785 ASSL-IGEPIDDLGIYILDEAQHPVPVGFVGEIYVGGAGVARGYLNRPELTAERFMADPF 843
Query: 167 --NSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
TGD+ +R +G + + GR DD +K G +I L + + + P + +
Sbjct: 844 IGTDAHMYRTGDLARLRRDGVLDFLGRTDDQVKIRGFRIELGEVAAALNAHPDIVQSEVI 903
Query: 224 WLQ---TPLLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ L+ Y A TL SQ + L L E P ++++D P +GK
Sbjct: 904 VREDEGQQKRLVGYVIAHKGITLESQLIRSSLTTCLPEAMIPAAIVQLDHFPLTINGKLD 963
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTI 336
++ L S ++ N + S L L + L E++ + +FF LGG S +A+ +
Sbjct: 964 RKALPKPMWNSVVI-NESSSSSPQELSLCRLFAELLGLENISPEDNFFELGGESLVAMRV 1022
Query: 337 CNKLSLTF 344
++ F
Sbjct: 1023 IARVRSDF 1030
>UniRef50_Q8GN23 Cluster: Peptide synthetase; n=1; Fischerella sp.
CENA19|Rep: Peptide synthetase - Fischerella sp. CENA19
Length = 582
Score = 60.5 bits (140), Expect = 2e-07
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 9/180 (5%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR-SCSCVWLQTP--L 229
TGD+G + +G + + GR+D +K G ++ L +E+ + Q P VR + V + P L
Sbjct: 343 TGDLGRWLPDGNIEFLGRIDHQVKIRGFRVELGEVETFLSQHPNVRENIVIVHQEEPGNL 402
Query: 230 LLIVYFSAET---LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L+ Y A+T S EL +FLK KL + P + +++LP GK ++ L
Sbjct: 403 QLVAYVVAKTEPVPSISELRNFLKEKLPDHMLPSTFVMLESLPIAPSGKVDRKALPKPDN 462
Query: 287 KSNILQNVENI-KSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
IL+ + ++ + + + K L E + FF LGG S + + +KL F
Sbjct: 463 LRPILETAYVLPRNEMEHTIADIWQKILKVEKVGIQDEFFDLGGHSLNVLQVYSKLRELF 522
>UniRef50_Q83Y49 Cluster: Non-ribosomal peptide synthetase; n=2;
Pseudomonas syringae|Rep: Non-ribosomal peptide
synthetase - Pseudomonas syringae
Length = 1328
Score = 60.5 bits (140), Expect = 2e-07
Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 8/179 (4%)
Query: 174 TGDIGEIRNGT-VFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV--WLQTPLL 230
TGD+ G + + GR D IK G +I +E + Q P V +CS + L
Sbjct: 1119 TGDLARWTPGRGIEFLGRSDSQIKIRGLRIEPGEVEQAIRQLPGVTACSLILRTLNLDKQ 1178
Query: 231 LIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKK 287
L+ + S + L Q++ L+ L + P +V ++ LP NA GK K L+ + +
Sbjct: 1179 LVAFVSLDGSVALDEQQIRVALRECLPDYMVPAEVHVIEQLPVNASGKVDKRALLELATQ 1238
Query: 288 SNILQ-NVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLSLTF 344
+ + E + L K + + LN D+ +++ FFS+GG S + I ++LS F
Sbjct: 1239 NGRARVTSERPSTALEKSIAEVWAHILNVPDVGRNEDFFSIGGHSLAGMRIMSRLSKQF 1297
>UniRef50_Q6VT95 Cluster: Mixed type I polyketide
synthase/nonribosomal peptide synthetase; n=3;
Bacteria|Rep: Mixed type I polyketide
synthase/nonribosomal peptide synthetase - symbiont
bacterium of Paederus fuscipes
Length = 8601
Score = 60.5 bits (140), Expect = 2e-07
Identities = 73/306 (23%), Positives = 137/306 (44%), Gaps = 29/306 (9%)
Query: 59 RSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDK 118
R +K+L GGEPL L++ + + ++ + L+G TE + W++V+ LDL K
Sbjct: 1478 RQGVKILC-GGEPLP--PALRQ-RFAESASQTWNLFGPTETTIWSTVSRLDLTK-----D 1528
Query: 119 EVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKN-------GNKEEN 167
V +G ++ T +++ + G++ +A L N E
Sbjct: 1529 SVDIGTPIANTRVYILNGDDQLVPIGVPGELCIAGDGLARGYLGNPQLTAQKFIANPFEP 1588
Query: 168 SIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+ R +G + + GR+D +K G++I L IE+ + + P V V +
Sbjct: 1589 GNRLYRTGDLARWREDGVLEHLGRLDQQVKVRGYRIELSDIETWLNRHPSVAQSLVVGHE 1648
Query: 227 TP--LLLIVYFSAET----LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
+LL+ Y+ ++ +SS EL ++L L E P + +P +GK ++
Sbjct: 1649 QAGGMLLVAYYVKDSEWASVSSTELRNYLAEHLPEYMVPAFFRALSNMPLMPNGKVDRKA 1708
Query: 281 LVNIYKKSNILQNVENIK-SYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICN 338
L + ++ + S + +E+ + L E + S FF +GG S L+V +
Sbjct: 1709 LSARELVAEESESGGRLPCSDIEREVLDIWRSLLAVEGIGVSVGFFEVGGNSILSVMLAQ 1768
Query: 339 KLSLTF 344
++S F
Sbjct: 1769 QISEAF 1774
>UniRef50_Q183T6 Cluster: D-alanine--poly(Phosphoribitol) ligase
subunit 1; n=3; Clostridium|Rep:
D-alanine--poly(Phosphoribitol) ligase subunit 1 -
Clostridium difficile (strain 630)
Length = 504
Score = 60.5 bits (140), Expect = 2e-07
Identities = 55/209 (26%), Positives = 95/209 (45%), Gaps = 18/209 (8%)
Query: 24 LFHEDNDNSVTFWQTTPS-KFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELK 82
LF + + + + W +TPS + + +K+L L+ + GE L+ + KEL
Sbjct: 225 LFRQFSISDIAVWVSTPSFAGVCITEKEFNSKML---PNLESMIFIGEALSK-NLTKELM 280
Query: 83 HKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHE----K 138
+ TRI YG TE + SV ++ K +K +P+G +S ++ + + K
Sbjct: 281 SRFPNTRIINGYGPTEATVGVSVNDMT-QKAIDDEKSLPVGYPMSNCKIKILDEDGNELK 339
Query: 139 NNTMGKIILASKTRKCILLNRKNGNKEENSIKFID--------TGDIGEIRNGTVFYRGR 190
N G+II+ + N K E ID TGD+G + +G ++Y GR
Sbjct: 340 ENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDGNIYYCGR 399
Query: 191 VDDTIKRFGHKINLHSIESTVMQCPRVRS 219
D IK G +I + IE+ + + V++
Sbjct: 400 KDFQIKLNGFRIEIEDIENNLRKVHNVKN 428
>UniRef50_Q12HS0 Cluster: Amino acid adenylation; n=1; Shewanella
denitrificans OS217|Rep: Amino acid adenylation -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 2378
Score = 60.5 bits (140), Expect = 2e-07
Identities = 87/350 (24%), Positives = 152/350 (43%), Gaps = 27/350 (7%)
Query: 40 PSKFFQH-SNENIKNKILCARSTLKVLALGGE--PLNGIKILKELKHKNNKTRIFTLYGV 96
P +FQ + K K S L+++ LGGE PL+ IK ++++ K ++F +YG
Sbjct: 1783 PPVYFQWLMRADAKQKQAWLDSPLRMVLLGGESMPLSVIKAWQQMQLPQ-KLQLFNVYGP 1841
Query: 97 TEMSCWASVAELD--LNKVTTGDKEVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKC 154
TE + ASV + N V GN +L +P I +
Sbjct: 1842 TEATITASVFPISAGFNDVKVSLGMPTEGNGFLVLDLQGKPVPAGVEGILYITGERLANG 1901
Query: 155 ILLNRKNGNKEENSIKFID------TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSI 207
L N + E I+ ID TGDI + + +GT+++ GR D +K G+++ L ++
Sbjct: 1902 YLFNEEKTT--EAFIEGIDGELMYHTGDIVKWLPDGTLWFVGRSDAQVKIRGYRVELDAV 1959
Query: 208 ESTVMQCPRVRSCSCVW---LQTPLLL--IVYFSAETLSSQELLDFLKCKLDEKYWPDKV 262
+ + + ++ Q LLL +V + T ++ L ++ +L +++
Sbjct: 1960 QHFLESREDIHEAVVLYNRIKQRDLLLAFVVASTEVTGVAKRTLASMRSELPHYMVANRI 2019
Query: 263 IRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQS-K 321
I VD +P A+GK + L+ + + N L+ + K L L+ + L +
Sbjct: 2020 IVVDQIPLTANGKVDSKALILLAE--NGLETNTTLSGTALK-LAVLIAQVLGQTPKSGDE 2076
Query: 322 SFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQ 371
SF+ LGG S A+ + + +S F G I L N I + + I Q
Sbjct: 2077 SFYDLGGDSLQALQLLSLISARF---GVDIALQQLLANSDINGLAELIDQ 2123
Score = 47.6 bits (108), Expect = 0.001
Identities = 66/318 (20%), Positives = 132/318 (41%), Gaps = 32/318 (10%)
Query: 3 EILLACTNGASLLIAPD---LTEVLFHEDN-DNSVTFWQTTPSKFFQHSNENIKNKILCA 58
EI G ++ I PD L LFH +N V+ TPS F+ + + N++
Sbjct: 704 EIFGPWLTGGAVAIVPDECLLQPALFHRFLLENKVSILNQTPSAFYNLIDAD--NQVDEP 761
Query: 59 RSTLKVLALGGEPLNGIKILK-ELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
S L+ + GGE L+ ++ + ++ ++ ++ +YG+TE + V +
Sbjct: 762 LSELRYVVFGGEALSLPRLASWQQRYDADRVKLVNMYGITETT--VHVTHYTVKAGDCKQ 819
Query: 118 KEVPLGNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKNGNKEENSIKFID 173
+G LS+ ++++ + T G++ + + G E + +F+
Sbjct: 820 ARSIIGLPLSDLDVYLLGSDGLPLPEGTKGELYIGGPG----VAREYFGKPEMTAQRFVT 875
Query: 174 ---------TGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSC--- 220
+GD + N G + Y GR DD +K G++I L + +M V++
Sbjct: 876 HTTAGRLYRSGDFARLDNDGQLVYLGRKDDQVKIRGYRIELEEVRQQLMSLDAVKTAVVT 935
Query: 221 -SCVWLQTPLL-LIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
S + L+ ++ AE + + L +L P ++ +P +GK
Sbjct: 936 VSDIGAGDKLIAFVIPQVAELFVASVIKHELAKRLPPYMIPAICHPIEHIPQTNNGKADI 995
Query: 279 EILVNIYKKSNILQNVEN 296
+ L++ YK+ +V+N
Sbjct: 996 KWLLSEYKRQQQSSSVQN 1013
>UniRef50_Q091C0 Cluster: Non-ribosomal peptide synthase; n=2;
Cystobacterineae|Rep: Non-ribosomal peptide synthase -
Stigmatella aurantiaca DW4/3-1
Length = 1443
Score = 60.5 bits (140), Expect = 2e-07
Identities = 78/342 (22%), Positives = 143/342 (41%), Gaps = 36/342 (10%)
Query: 30 DNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTR 89
+ +F + TPS K+L LGGE L+ L + + TR
Sbjct: 762 EQDFSFIKMTPSHLRAFDGLGRARKVL---ERAHAAVLGGEGLHAGD-LATWREQRIATR 817
Query: 90 IFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKI 145
I YG TE + V ++ ++ +P+G + T+L++ + G++
Sbjct: 818 IINEYGPTEAAVACCVYDVPQGGEPLPER-IPIGRPIDNTQLYILDRHRQPVPIGVPGEL 876
Query: 146 ILASKTRKCILLNRK---------NGNKEENS----IKFIDTGDIGE-IRNGTVFYRGRV 191
+ L R N + E S + TGD+ + +G + + GRV
Sbjct: 877 HIGGTGLARGYLRRPDLTAERFIPNPFQSETSGSGGDRLYRTGDLARYLPDGRIEFLGRV 936
Query: 192 DDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL---QTPLLLIVYFSAETLS------- 241
D +K GH++ IE+ + + PRV + V +P L+ Y A+ L+
Sbjct: 937 DSQLKIRGHRVEAGEIEAALARHPRVVQAAVVLRHVPNSPPRLVAYVQAKALAEGDAAVL 996
Query: 242 SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIK--S 299
+E FL+ ++ + P +D LP GK ++ L + +++ + + S
Sbjct: 997 KEEFRKFLRGQIPDYMIPGAFEVLDELPLTPSGKIDRKALPPLATEAHGASALVRTRGAS 1056
Query: 300 YLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
++L+AL ++ L E + + SFF LGG S LA+T+ ++
Sbjct: 1057 ETERQLEALFSELLGLEAVSPNASFFELGGHSLLAITLIARI 1098
>UniRef50_A6T7J0 Cluster: Crotonobetaine/carnitine-CoA ligase; n=1;
Klebsiella pneumoniae subsp. pneumoniae MGH 78578|Rep:
Crotonobetaine/carnitine-CoA ligase - Klebsiella
pneumoniae subsp. pneumoniae MGH 78578
Length = 542
Score = 60.5 bits (140), Expect = 2e-07
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 7/122 (5%)
Query: 171 FIDTGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV------ 223
+ DTGDIG + NG + R D IK G I+ +E+ + P VRS + +
Sbjct: 412 WFDTGDIGTLDANGYLVISDRAKDIIKSGGEWISTVELENIAIAHPGVRSAAAIAARHPR 471
Query: 224 WLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
W + P+LL V + +LL + + ++ + PD+VI VD LP +A GK K L
Sbjct: 472 WDERPVLLCVRAEGGEVEETDLLSWFEKRVPKWQIPDRVIFVDALPVSATGKVLKNQLRQ 531
Query: 284 IY 285
Y
Sbjct: 532 AY 533
>UniRef50_A5FI48 Cluster: Amino acid adenylation domain; n=2; cellular
organisms|Rep: Amino acid adenylation domain -
Flavobacterium johnsoniae UW101
Length = 2894
Score = 60.5 bits (140), Expect = 2e-07
Identities = 49/189 (25%), Positives = 91/189 (48%), Gaps = 8/189 (4%)
Query: 163 NKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
N E K TGD+ + +G + Y GR D+ +K G+++ L IE + + S +
Sbjct: 1611 NPFEPEEKLYKTGDLARWLPDGNLEYVGRKDNQVKIRGNRVELGEIEYVIREFDSAISNA 1670
Query: 222 CVWLQT----PLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
V ++ P ++ Y + +++ +EL +LK KL + P + ++TL NA+GK
Sbjct: 1671 VVLVKEVKNEPFIIAYYTTGKSVDKKELRKYLKDKLADYMIPAYYVELETLQLNANGKVD 1730
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKD-LNYEDL-QSKSFFSLGGTSFLAVT 335
L I +S+I++ + +E A++ ++ L ++ + FF LGG S L
Sbjct: 1731 LSKLPAI-SESDIVKKEYIAPANQTEEKIAVIWQELLGHQKIGAGDDFFELGGHSLLLTK 1789
Query: 336 ICNKLSLTF 344
+ N+ F
Sbjct: 1790 LLNEYQRVF 1798
Score = 44.4 bits (100), Expect = 0.012
Identities = 71/311 (22%), Positives = 130/311 (41%), Gaps = 32/311 (10%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
T++++ LGGE + + +H + YG TE + A +++T + +
Sbjct: 2549 TVRLVDLGGESCHKSDLELFKEHFLEGAFLVNDYGPTESTIVAQKFLSHESELTRNN--M 2606
Query: 121 PLGNCLSETELFVQPHEKNNT------MGKIILASKTRKCILLNRKNGNKE-------EN 167
PLG + ET++F+ ++NN G+I+ S LNR+ +
Sbjct: 2607 PLGKSVEETKVFLL--DENNKPKGIYQTGEIVFKSDYLSLGYLNRQELTDKVFTTDPLTG 2664
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW-- 224
+ + +GDIG + +G + + R D +K G +I L IE + Q + +
Sbjct: 2665 NGRVYKSGDIGMMLPSGEIEFLQRKDSQVKINGLRIELSEIEYQLEQIEFINEAVVLLKE 2724
Query: 225 LQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYW-PDKVIRVDTLPTNAHGKTSKEILVN 283
LQ + Y +E + + L K+ KY P I ++ P GK ++ L +
Sbjct: 2725 LQENSYITAYVRSEEILDVTKIKLLLGKILPKYMIPAIYISMENFPLTRTGKIERKALPD 2784
Query: 284 --IYKKSNI-----LQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTI 336
I + +VE+ +++ E+ L + D +FF LGG S AV +
Sbjct: 2785 PVISDLKTVPYEAPANDVESRLVHIWAEVLKLDPAVIGTND----NFFELGGNSLQAVVL 2840
Query: 337 CNKLSLTFPEV 347
NK++ + V
Sbjct: 2841 INKINKIYNTV 2851
>UniRef50_A4X8R2 Cluster: Amino acid adenylation domain; n=1;
Salinispora tropica CNB-440|Rep: Amino acid adenylation
domain - Salinispora tropica CNB-440
Length = 2174
Score = 60.5 bits (140), Expect = 2e-07
Identities = 75/298 (25%), Positives = 131/298 (43%), Gaps = 26/298 (8%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+++ L G+ + G+ + L+ + R L G TE + W++ E + +V + VP
Sbjct: 1841 LRLVLLSGDWV-GLDLPGRLRRHQPEARFVALGGATEAAIWSNACE--VGEVPAHWRSVP 1897
Query: 122 LGNCL-SETELFVQPHEKNN---TMGKIILASKTRKCILLNRKNGNKEENSIKFID---- 173
G L ++ V P ++ G++ + + + G+ E + +F++
Sbjct: 1898 YGRPLRNQCYRVVDPRGRDCPDWVAGELWIGGAG----VAHGYRGDPETTARQFVNTDDG 1953
Query: 174 ----TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL--- 225
TGD+G +GT+ + GR D +K GH+I L IE+ P V + +
Sbjct: 1954 RWYRTGDLGRYWPDGTLEFLGRSDFQVKIRGHRIELGEIEAAAEAHPAVARAVALTVGEG 2013
Query: 226 -QTPLLLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L L V SA T + + L L +L P++V V TLP A+GK + L
Sbjct: 2014 RHRRLALTVVPSAGTAVDTTALAGLLAQRLPSYMVPEQVHEVPTLPLTANGKVDRRALTA 2073
Query: 284 IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + E + K + L + L+ + L + +SFF+LGG S LA + L
Sbjct: 2074 RLGPDAVEEWEEPPRGDREKLIAELWVEVLDCDQLGRQQSFFALGGDSLLATRLVELL 2131
Score = 56.4 bits (130), Expect = 3e-06
Identities = 71/321 (22%), Positives = 141/321 (43%), Gaps = 26/321 (8%)
Query: 31 NSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRI 90
+ VT WQ+ P+ + R L++ LGG+ + G+ + L + +
Sbjct: 782 HGVTVWQSVPALLDMLLSAAAPADQ--TRLPLRLALLGGDWV-GLDLAGRLTTQAPAATL 838
Query: 91 FTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKNN----TMGKII 146
L G TE + ++V + + +T + VP G L+ + V + G++
Sbjct: 839 VALGGTTETAIHSTVQVVPVPIPSTW-RSVPYGLPLANQHMRVADRAGRDRPDWVTGELW 897
Query: 147 LASKTRKCILLNRKNGNKEENSIKFID--------TGDIGEIR-NGTVFYRGRVDDTIKR 197
+ ++ + N G+ E + F++ TGD+ +GTV + GR D +K
Sbjct: 898 IGGRS----VANGYRGDPERTARTFVELGGVRWYRTGDLARYHPDGTVEFLGRADAQVKI 953
Query: 198 FGHKINLHSIESTVMQCPRVRSCSCVWLQTP--LLLIVYFSAETLSSQELLDFLKCKLDE 255
GH+I L IE+ + + P VR V L TP L V +A+ + +L DFL ++
Sbjct: 954 RGHRIELGEIEAALERHPAVRRAVVVALGTPRRLAAAVIVTAD-VDPPDLRDFLAGQVPA 1012
Query: 256 KYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNI-LQNVENIKSYLFKELKALVNKDLN 314
P++V+ LP + + K + + + + + +E + +++ + + L
Sbjct: 1013 YMVPEQVVPTGQLPLSVNAKIDRRAVARSIEAARAEPETLEEPVGDIERDVARIWAELLG 1072
Query: 315 YEDL-QSKSFFSLGGTSFLAV 334
+ + ++FF+ GG S +A+
Sbjct: 1073 VPAVGRRQTFFAAGGDSLVAI 1093
>UniRef50_Q4ZV21 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=3; Pseudomonas syringae group|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 2666
Score = 60.1 bits (139), Expect = 2e-07
Identities = 89/356 (25%), Positives = 147/356 (41%), Gaps = 31/356 (8%)
Query: 3 EILLACTNGASLLIAP-DLTEVL--FHEDN-DNSVTFWQTTPSKFFQHSNENIKNKILCA 58
EI A +G L+I P ++T FH + VT TPS F Q + + +
Sbjct: 2252 EIFGALLHGGRLVIVPREVTRSPEDFHALLVEQQVTVLNQTPSAFKQLMHVACDSSL--- 2308
Query: 59 RSTLKVLALGGEPLNGIKILKE--LKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
+L+ + GGE L+ + LK + + ++ +YG+TE + S + L T
Sbjct: 2309 PMSLQTVIFGGEALD-VASLKPWFARFGDQSPQLINMYGITETTVHVSYRPITL--ADTQ 2365
Query: 117 DKEVPLGNCLSETELFVQPHEKNNT---------MGKIILAS--KTRKCILLNRKNGNKE 165
+ P+G + + +V + N +G LA R + R +
Sbjct: 2366 NPASPIGEAIPDLSWYVLDADFNPVAQGCSGELHIGHAGLARGYHNRAALTAERFVPDPF 2425
Query: 166 ENSI-KFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
N + TGD+ R G + Y GR+D +K G +I L IE+ + P VR S +
Sbjct: 2426 SNEGGRLYRTGDLARYRATGVIDYAGRIDHQVKIRGFRIELGEIEARLQAHPAVREVSVL 2485
Query: 224 WLQTPLLLIVYFSAETLSSQELLDFLK----CKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
L L + + L + LK L + P I +D++P A+GK ++
Sbjct: 2486 ALDGQLAAYLVPAEPDQDQPTLREMLKNELRAHLPDYMVPTHFIVLDSMPLTANGKLDRK 2545
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAV 334
L S + + L ++L A+ L E + ++ +FF LGG S LAV
Sbjct: 2546 AL-PAPDASQLQATYSAPQGELEQQLAAIWADLLQVERVGRNDNFFELGGHSLLAV 2600
Score = 43.6 bits (98), Expect = 0.020
Identities = 44/163 (26%), Positives = 72/163 (44%), Gaps = 12/163 (7%)
Query: 183 GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL-----QTPLLLIVYFSA 237
G + + GR DD +K G+++ + ++ V S + L Q L L+ Y A
Sbjct: 952 GLLEFIGRADDQVKVRGYRVEPAEVARVLLGLASVAQVSVLALPIDDDQARLQLVAYCVA 1011
Query: 238 E---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNV 294
LS L + L L + P +++ +D+LP A+GK K L K + Q
Sbjct: 1012 AGGADLSIDSLREQLTACLPDYMVPAQIMLLDSLPLTANGKLDKRALP---KPGVVKQRY 1068
Query: 295 ENIKSYLFKELKALVNKDLNYEDLQS-KSFFSLGGTSFLAVTI 336
+ ++L A+ L E + S +FF LGG S L++ I
Sbjct: 1069 TAPVGEIEEKLAAVWADVLKLEQVGSTDNFFELGGDSILSLQI 1111
>UniRef50_Q4KCD8 Cluster: Nonribosomal peptide synthase; n=2;
cellular organisms|Rep: Nonribosomal peptide synthase -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 6675
Score = 60.1 bits (139), Expect = 2e-07
Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 6/114 (5%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP---- 228
TGD + +G + GR D +K G +I L IE+T+ P + S + V +Q P
Sbjct: 423 TGDEARFLDDGQIEVLGRFDSQVKLRGFRIELGEIENTLKSHPGI-SDAVVLVQDPGSED 481
Query: 229 LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
L+ Y A+ L + + DF+K +L E P++V V+ +P AHGKT ++ L+
Sbjct: 482 PKLVAYVVAQGLDKKTIRDFVKARLPEYMTPNRVQFVEQIPVTAHGKTDRQALL 535
>UniRef50_Q9F848 Cluster: CmlH; n=1; Streptomyces venezuelae|Rep:
CmlH - Streptomyces venezuelae
Length = 968
Score = 60.1 bits (139), Expect = 2e-07
Identities = 71/299 (23%), Positives = 128/299 (42%), Gaps = 22/299 (7%)
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
ARS ++ + GE L + K ++ +R+F YG TE + S+AEL + G
Sbjct: 255 ARSRIRKVEFCGEALGEGEYDKAARY----SRVFNAYGPTEATVCFSLAELTSYTPSIGT 310
Query: 118 KEVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSI-KFID--- 173
+ + + H T G++++ + L G+ EN + +D
Sbjct: 311 PVDGFRAYVRDPDS--GDHATAGT-GELVIVGDG---VALGYAGGSPAENEVFGTVDGSP 364
Query: 174 ---TGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL 229
TGD+ + + G + Y GR+D+ IKR GH++NL + ST+ + R + V +
Sbjct: 365 AYATGDVVSLSDDGELTYLGRIDEQIKRLGHRVNLAHVGSTLSR-HLGREVALVRQDATI 423
Query: 230 LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSN 289
LL+ E + + L+ ++ + PD+++ VD LP + GK + L +
Sbjct: 424 LLVTAADGEA-TEESLMARIRDLVPVWEAPDRLVLVDALPLTSGGKVDRSALRELLASPA 482
Query: 290 ILQN--VENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTFPE 346
+ + + + + +V L E S F GG+S + I KLS + E
Sbjct: 483 GAPHGGTDGEDAAELRRVLDVVTAVLGQEIGPETSIFDAGGSSLAMIQIQVKLSDAYGE 541
>UniRef50_Q7WSZ1 Cluster: D-alanine-D-alanyl carrier protein ligase;
n=2; Bacillus licheniformis|Rep: D-alanine-D-alanyl
carrier protein ligase - Bacillus licheniformis
Length = 502
Score = 60.1 bits (139), Expect = 2e-07
Identities = 56/208 (26%), Positives = 95/208 (45%), Gaps = 16/208 (7%)
Query: 22 EVLFHEDNDNSVTFWQTTPSKFFQHS--NENIKNKILCARSTLKVLALGGEPLNGIKILK 79
++LF ++V W +TPS F Q + + ++L L + GE L + +
Sbjct: 223 KLLFEALKQSNVNVWTSTPS-FAQMCLMDPSYSEELL---PELSLFMFCGETLPA-SVAR 277
Query: 80 ELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHE-- 137
+LK + K R+F YG TE + + E+ + V +P+G+ ETE+ + +
Sbjct: 278 QLKERFPKARVFNTYGPTEATVAVTSIEVT-DDVLNKYSSLPVGSEKPETEIVIINEDGK 336
Query: 138 --KNNTMGKIILASKTRKCILLNRKNGNKEE----NSIKFIDTGDIGEIRNGTVFYRGRV 191
++ G+II+ + L K ++ N TGD G NG +F+ GR+
Sbjct: 337 AVQDGEKGEIIITGASVSKGYLGEKALTEKAFFSYNGSPAYRTGDAGYKENGQLFFLGRL 396
Query: 192 DDTIKRFGHKINLHSIESTVMQCPRVRS 219
D IK G++I L IE + Q V+S
Sbjct: 397 DFQIKLHGYRIELEEIEYQINQSRYVQS 424
>UniRef50_Q1GTX6 Cluster: AMP-dependent synthetase and ligase; n=5;
Sphingomonadales|Rep: AMP-dependent synthetase and
ligase - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 534
Score = 60.1 bits (139), Expect = 2e-07
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 7/123 (5%)
Query: 171 FIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV------ 223
+ DTGD+ + +G + R D IK G I+ +E+ + P V+ + V
Sbjct: 402 WFDTGDVSVLHPDGVMQITDRAKDVIKSGGEWISSIELENAAVGAPGVQEAAAVGVYHPK 461
Query: 224 WLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
W + P+LLIV +S ++++LK K+ + + PD+V+ VD LP A GK K + +
Sbjct: 462 WDERPILLIVKKPGAEVSEAAIIEYLKDKVAKWWLPDEVVFVDELPHTATGKILKRQIRD 521
Query: 284 IYK 286
YK
Sbjct: 522 DYK 524
>UniRef50_Q0LP45 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1528
Score = 60.1 bits (139), Expect = 2e-07
Identities = 54/209 (25%), Positives = 98/209 (46%), Gaps = 13/209 (6%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSC-SCVWLQTP--L 229
+GD+ + +G + Y GR+D +K G +I L IE+T+ P V + + + P
Sbjct: 862 SGDLVRYLPDGNLEYLGRIDQQVKLHGFRIELGEIEATLASHPTVHAAVAMIREDRPGHK 921
Query: 230 LLIVYFSAETLSSQE---LLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L+ Y AE ++Q+ +L + +L P VI +D+LP +GK ++ L
Sbjct: 922 RLVAYVVAEPTANQDTSIVLTHVAQQLPHYMLPSVVIWLDSLPLTPNGKVDRQALPAPEI 981
Query: 287 KSNILQNVENIKSYLFK-ELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLSLTF 344
L + + ++ +L A+ + L + + + +FFSLGG S L + +
Sbjct: 982 NQTALDSAQTTPLDQYEAQLMAIWQRVLGLKAVDRHANFFSLGGDSILVMQVVG----IA 1037
Query: 345 PEVGKHILPHLLSHNKSIGDVLKTITQDT 373
+ G + P LL N++I + + I Q T
Sbjct: 1038 RQHGLILTPRLLFQNQTIASLAQAIRQQT 1066
>UniRef50_Q0LP29 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1553
Score = 60.1 bits (139), Expect = 2e-07
Identities = 54/209 (25%), Positives = 97/209 (46%), Gaps = 13/209 (6%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW---LQTPL 229
TGD+ + +G + + GR+D +K G +I L IE+ + Q P +R V L
Sbjct: 879 TGDLARYQVDGNLEFLGRIDQQVKIRGFRIELGEIEAVLAQHPSIREAVVVAREDLPGDK 938
Query: 230 LLIVYFSAETLSSQ---ELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL-VNIY 285
L+ Y AE+ EL FL+ KL E P + +++LP +GK ++ L V
Sbjct: 939 RLVAYLIAESEQMPHIGELRAFLQTKLPEYMLPAAFMVLESLPLTRNGKVDRQALPVPPT 998
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
+ ++ + L L + + L E + +FF LGG S L++ I +L+
Sbjct: 999 TREHLANQFAAPTNQLETLLSTIWAEVLGREQVGIHDNFFELGGDSILSLQIVARLN--- 1055
Query: 345 PEVGKHILPHLLSHNKSIGDVLKTITQDT 373
+ G H+L + ++I ++ + ++ T
Sbjct: 1056 -QAGYHVLTKDIFQYQTIAELAQVVSSTT 1083
>UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 2419
Score = 60.1 bits (139), Expect = 2e-07
Identities = 66/303 (21%), Positives = 145/303 (47%), Gaps = 28/303 (9%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKT-RIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
TL+++ LGG+ L ++K+++ T RI+ YG TE S ++ +++ ++
Sbjct: 2074 TLEIVHLGGDALQPA-LVKQIQALVAPTCRIYNGYGPTEASVNCAIYQVEPERLADV-VN 2131
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE---NSI--- 169
VP+G + +L++ + +G++ +A + LN+ + E+ N
Sbjct: 2132 VPIGRVTANHQLYILDAQLRPVPIGVVGELCVAGPSLSQGYLNQPALSAEKFVPNPFAAQ 2191
Query: 170 ---KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
+ TGD+ + +G + + GR+D +K G++I L IE+ ++ P V+ +
Sbjct: 2192 PGQRLYRTGDVARYLPDGLIEHLGRIDHQVKVRGYRIELGEIEAALLNHPAVQEAVVLPT 2251
Query: 226 QTPLLL--IVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L+ +V A + + EL +FL+ +L P ++ +++LP A+GK +++ L+
Sbjct: 2252 SEASLIGYVVLKQAGSTPTSELREFLQQRLPGYMLPAILVPLESLPRTANGKINRQALLA 2311
Query: 284 I----YKKSNILQNVENIKSYLFKELKALVNKD-LNYEDLQSKSFFSLGGTSFLAVTICN 338
+++ + I+ + + ++ +D ++ D +FF +GG S L +
Sbjct: 2312 TSALPERETPFVAPQGEIEEAVVQIWMEVLKRDQISVHD----NFFHIGGHSLLGTQVIY 2367
Query: 339 KLS 341
KL+
Sbjct: 2368 KLA 2370
>UniRef50_A3IZB3 Cluster: Amino acid adenylation; n=2;
Chroococcales|Rep: Amino acid adenylation - Cyanothece
sp. CCY 0110
Length = 1178
Score = 60.1 bits (139), Expect = 2e-07
Identities = 81/351 (23%), Positives = 153/351 (43%), Gaps = 27/351 (7%)
Query: 15 LIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNG 74
LI DL +++ D +V+ P Q + +N+I A + L+++ GGE L+
Sbjct: 442 LIPSDLNKIII----DFNVSVVDLPPGYLTQWLHCLEQNRISTAINKLRLVISGGETLSL 497
Query: 75 IKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNK-VTTGDKEVPLGNCLSETELFV 133
I K + + YG TE + A + +K + + +P+G L + ++
Sbjct: 498 NTIEKWYQSPLKDISLINAYGPTEATITAITFLVPKDKKLIELYRTIPIGRPLPNRKTYI 557
Query: 134 QPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE---NSIKF---IDTGDIGE-IRN 182
+KN +G++ + + C LN+ +E+ N + TGD+ + +
Sbjct: 558 LDTQKNPVPIGVVGELYIGGEGLACGYLNQFELTQEKFINNPFEIGQLYKTGDLARYLTD 617
Query: 183 GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL------QTPLLLIVYFS 236
G + + GR+D+ +K G +I L IE+ + + VR + Q + I+
Sbjct: 618 GNIEFLGRIDNQVKLRGFRIELGEIETILTKYSYVREAKIMIREDNYSNQRLVAYIILNP 677
Query: 237 AETLS---SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQN 293
+T S SQ++ ++L+ KL P I ++T P +GK S + +N
Sbjct: 678 CQTSSLKISQQIKEYLQEKLPNYMIPSVFIILETFPLTPNGKIDYHSFPE-PDFSTLKKN 736
Query: 294 VENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLT 343
++ K L L ++ L E++ + +FF LGG S LA + + + T
Sbjct: 737 YIAPRTTEQKILANLWSQVLKIENIGINDNFFELGGHSLLATQLVSLVKET 787
>UniRef50_Q0CBA1 Cluster: Predicted protein; n=2; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 1001
Score = 60.1 bits (139), Expect = 2e-07
Identities = 66/328 (20%), Positives = 145/328 (44%), Gaps = 30/328 (9%)
Query: 69 GEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSE 128
GE N + L+ ++ YG TE ++++ + +++ + + +G +
Sbjct: 269 GEAANIAAMTAVLESSGPPKNLWNTYGPTETLVFSTLHPVTPSELQYSN--ISIGKPFGD 326
Query: 129 TELFVQPHEKN-----NTMGKIILASKTRKCILLNRKNGNKEE-----NSIKFIDTGDIG 178
T+L + E N G+I+L + + R N+ N ++ TGD+
Sbjct: 327 TKLLLVDSESNPITEPGKTGEILLGGPSLTPGYIGRPEENESRFVISTNGTRYYKTGDLA 386
Query: 179 EIRNGT---VFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT-----PLL 230
R + + GRVD +K+ G ++ L+ IE ++ + + V ++ P L
Sbjct: 387 RWRPDDPDLLEFAGRVDLQVKQGGFRVELNEIEQNLLASKALSAAIVVQVRPSDDSDPFL 446
Query: 231 L--IVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY--- 285
+ ++ ++ ++ ++L++ ++ ++ + P + P HGK ++ L + Y
Sbjct: 447 VGYVIPAASNSVRKRQLVEHMEKRVPDYMVPRDFVFCSKFPITEHGKVDRKGLKDRYLQH 506
Query: 286 -KKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLSLT 343
++S +NV L +++ + + LN ++ +S FFSL GTS A ++ +S
Sbjct: 507 QEQSRTDENVNGKSLDLAAQIRNIWSSLLNISEIKESDDFFSLRGTSIQAASM---ISTI 563
Query: 344 FPEVGKHILPHLLSHNKSIGDVLKTITQ 371
++GK I L N D+++ I +
Sbjct: 564 QKQLGKTISMRALFENSRFKDLVQYIEE 591
>UniRef50_Q9HYR8 Cluster: Probable non-ribosomal peptide synthetase;
n=5; Pseudomonas aeruginosa|Rep: Probable non-ribosomal
peptide synthetase - Pseudomonas aeruginosa
Length = 2352
Score = 59.7 bits (138), Expect = 3e-07
Identities = 57/240 (23%), Positives = 103/240 (42%), Gaps = 20/240 (8%)
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
A S+L+++ GE L +++ + + + R+ LYG TE A+V D +
Sbjct: 704 AASSLRLVFCSGEALAPLQVARFRRLFGDAVRLVNLYGPTE----ATVDVSDHECASDNP 759
Query: 118 KEVPLGNCLSETELFVQPH----EKNNTMGKIILASKTRKCILLNRKNGNKEENSI---- 169
VP+G + L+V + +G++ + LNR N E +
Sbjct: 760 TRVPIGRPIDNLRLYVLDRALRPQPLGAVGELYIGGVGVARGYLNRPELNAERFLVDPFV 819
Query: 170 ---KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL 225
+ TGD+ + +G + Y GR DD +K G+++ + + P VR + V
Sbjct: 820 AGGRLYRTGDLARWLADGNLEYLGRADDQVKIRGNRVEPDEVRDRLAALPGVRDAAVVAR 879
Query: 226 QTPL----LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
+ + L+ Y +A L +L L L + P +R+D+LP +A+GK + L
Sbjct: 880 DSAVRGTHLVGYYVAAAELDPGQLRAGLSATLPDFMLPAFFVRIDSLPLSANGKLDRRQL 939
Score = 35.9 bits (79), Expect = 4.0
Identities = 45/174 (25%), Positives = 72/174 (41%), Gaps = 15/174 (8%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVM----QCPRVRSCSCVWLQTP 228
TGD+G I NG + + GR D +K G +I +E +M + P +R + V +
Sbjct: 1852 TGDLGRILGNGEIVWLGRADTQVKVRGFRIEPAEVELAIMRQAERQPGLRGAAVVARERQ 1911
Query: 229 -----LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L + E + EL L+ +L E P VD GK L
Sbjct: 1912 GNDAFLAAFLLGEPEAVDLAELKQALRSELPEHMVPAHFAWVDGFALTPSGKRDDAALRA 1971
Query: 284 IYKKSNILQNVENI--KSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAV 334
+ + N+E + + + L L+ + L+ + + SFF LGGTS A+
Sbjct: 1972 LPLEHG--TNIEYLAPRDDYERTLAGLLGELLDRPRVGIRDSFFDLGGTSLSAM 2023
>UniRef50_Q6LGA3 Cluster: Hypothetical peptide synthetase; n=1;
Photobacterium profundum|Rep: Hypothetical peptide
synthetase - Photobacterium profundum (Photobacterium sp.
(strain SS9))
Length = 2168
Score = 59.7 bits (138), Expect = 3e-07
Identities = 69/299 (23%), Positives = 128/299 (42%), Gaps = 33/299 (11%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ +A+GGE + ++H +K +F +YG TE + A V +L+ D+ V
Sbjct: 777 LQAVAIGGEACPA----QLVEHWADKVALFNMYGPTEFTVTALVQQLET------DQPVS 826
Query: 122 LGNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKNGNKEE--------NSI 169
+G ++ T+ + N G++ L LN+ + ++
Sbjct: 827 IGTNVTNTQALILDQSGNLCPNGVPGELCLTGLGLARGYLNQPELTAQAFIQWQCLGKTV 886
Query: 170 KFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIES-TVMQCPRVRSCSCVWL-Q 226
+ TGD + + G V Y GR+D+ +K G++I L IE+ V+ + + Q
Sbjct: 887 RMYKTGDKARVNHDGRVEYMGRIDEQVKLRGYRIELGEIEAQLVLAHENIHQVKVIVAEQ 946
Query: 227 TPLLLIVYF-----SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
P ++V + SA +++ +L+ + L E P ++ +D +P +GK L
Sbjct: 947 GPQKVLVAYATLRESALAVAASTILNHVARTLPEYMVPAQLFFIDDMPLTVNGKLDIRQL 1006
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKL 340
N+ N + + L + A+ LN + FF LGG S L++ + KL
Sbjct: 1007 PNV--DLNAVTSTAPTND-LESAVLAIWQSTLNTSCGVEEDFFRLGGDSILSIQLTTKL 1062
>UniRef50_Q2RJ14 Cluster: AMP-dependent synthetase and ligase; n=1;
Moorella thermoacetica ATCC 39073|Rep: AMP-dependent
synthetase and ligase - Moorella thermoacetica (strain
ATCC 39073)
Length = 546
Score = 59.7 bits (138), Expect = 3e-07
Identities = 63/262 (24%), Positives = 116/262 (44%), Gaps = 19/262 (7%)
Query: 32 SVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIF 91
S+TF+ P+ + + ++ L L+ A GG + I+ +K++K +
Sbjct: 287 SITFFHAAPTVYIMLLEQGYRHYQL---PDLRKAACGGGAIP-IETIKKIKTWIPQLEFH 342
Query: 92 TLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKNNTMGKIILASKT 151
T+YG+TE S S A L V T + G + + V E + GK +
Sbjct: 343 TVYGLTETS---SPATLFPGDVATSPRIGTSGIPIPVVDCKVIDAEGRDITGKGVGELCI 399
Query: 152 RKCILLNRKNGNKEENSIKF----IDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHS 206
R ++ + N E + F TGD+ I +G V+ R+ D I R G KI
Sbjct: 400 RGPVVTQQYWNNDEATTRAFQGGWFRTGDVARIDGDGYVYIMDRLKDMINRGGEKIYSLE 459
Query: 207 IESTVMQCPRVRSCSCVWLQTPL-------LLIVYFSAETLSSQELLDFLKCKLDEKYWP 259
+E+ + P V+ + + P+ +++ +++ +E+ D+++ +L + P
Sbjct: 460 VENVIYSHPGVKEVAVIGSVDPIYGEVARAVVVPNNHGSSITGREIQDWVRARLAKYKVP 519
Query: 260 DKVIRVDTLPTNAHGKTSKEIL 281
V V+ LP NA+GK K++L
Sbjct: 520 QYVNFVNELPKNANGKIDKKLL 541
>UniRef50_Q9Z5F4 Cluster: Ta1; n=4; Bacteria|Rep: Ta1 - Myxococcus
xanthus
Length = 2393
Score = 59.7 bits (138), Expect = 3e-07
Identities = 88/372 (23%), Positives = 159/372 (42%), Gaps = 52/372 (13%)
Query: 2 VEILLACTNGASLLIAPDLT----EVLFHEDNDNSVTFWQTTPSKF---FQHSNENIKN- 53
+E+LL GA ++IA T + L + T Q TP+ + FQ EN +
Sbjct: 626 LELLLPLCAGAQVIIASAETVRDAQALKRALRTHRPTLMQATPATWTLLFQSGWENAERV 685
Query: 54 KILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKV 113
+ILC GGE L + LK + ++ ++G TE + W+++A++ ++
Sbjct: 686 RILC----------GGEALP--ESLKA-HFVRTASDVWNMFGPTETTIWSTMAKVSASRP 732
Query: 114 TTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKN-------G 162
T +G + T+++V G++ +A C LNR
Sbjct: 733 VT------IGKPIDNTQVYVLDDRMQPVPIGVPGELWIAGAGVACGYLNRPALTAERFVS 786
Query: 163 NKEENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
N TGD+ R +G V Y GR+D +K G +I + IE+ + P V++C+
Sbjct: 787 NPFTPGTTLYRTGDLARWRADGEVEYLGRLDHQVKVRGFRIEMGEIEAQLAGHPSVKNCA 846
Query: 222 CV--WLQTPLLLIVYF--SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
V L L+ Y + + + + L+ L + P V VD +P + +GK
Sbjct: 847 VVAKELNGTSQLVAYCQPAGTSFDEEAIRAHLRKFLPDYMVPAHVFAVDAIPLSGNGKVD 906
Query: 278 KEIL----VNIYKKSNILQNVENIKSYLFKELKALVN-KDLNYEDLQSKSFFSLGGTSFL 332
+ L V +K++ + +++ L + K ++ ++ ED FF +GG S L
Sbjct: 907 RGQLMARPVVTRRKTSAVHARSPVEATLVELWKNVLQVNEVGVED----RFFEVGGDSVL 962
Query: 333 AVTICNKLSLTF 344
A + +++ F
Sbjct: 963 AAVLVEEMNRRF 974
>UniRef50_Q84BC7 Cluster: NcpB; n=3; Cyanobacteria|Rep: NcpB - Nostoc
sp. ATCC 53789
Length = 4803
Score = 59.7 bits (138), Expect = 3e-07
Identities = 49/182 (26%), Positives = 88/182 (48%), Gaps = 8/182 (4%)
Query: 167 NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR-SCSCVW 224
+S + TGD+ + +G + Y GR+D+ +K G +I L IE+ + Q V+ SC+ V
Sbjct: 3110 SSERLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAVLSQHINVQASCAVVR 3169
Query: 225 LQTP-----LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
TP + IV + +S + FLK KL E P ++ ++ LP ++GK +
Sbjct: 3170 EDTPGDKRLVAYIVPQPEQRVSVNVVRSFLKEKLPEYMLPSAIVILEALPITSNGKLDRR 3229
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICN 338
+L S + ++ + + L + + L E + +FF LGG S LA + +
Sbjct: 3230 VLPAPDLHSQLSDQYVAPRNPIEEILSLIWAQVLKVELVGIHDNFFELGGHSLLATQLVS 3289
Query: 339 KL 340
++
Sbjct: 3290 RI 3291
Score = 59.3 bits (137), Expect = 4e-07
Identities = 50/186 (26%), Positives = 87/186 (46%), Gaps = 8/186 (4%)
Query: 167 NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR-SCSCVW 224
+S + TGD + +G + Y GR+DD +K G +I L IE+ + Q V+ SC V
Sbjct: 881 SSERLYKTGDKARYLSDGNIEYLGRIDDQVKIRGLRIELGEIEAVLSQHSDVQVSCVIVR 940
Query: 225 LQTP--LLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
TP L+ Y + E+ FLK KL + P ++ +++ P +GK +
Sbjct: 941 EDTPGDKRLVAYIVTHQDCQPTMGEIRQFLKAKLPDYMIPSAIVILESFPLTPNGKIDRR 1000
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICN 338
L + +L+ ++ + + L L + L E + +FF LGG S LA + +
Sbjct: 1001 ALPKPDLDTALLEKYVAPRTPVEEMLALLWAQVLKVEQVGIYDNFFELGGHSLLATQLVS 1060
Query: 339 KLSLTF 344
++ +F
Sbjct: 1061 RIRTSF 1066
Score = 58.4 bits (135), Expect = 7e-07
Identities = 51/193 (26%), Positives = 92/193 (47%), Gaps = 9/193 (4%)
Query: 161 NGNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRS 219
N S + TGD+ + +G + Y GR+D+ IK G +I + IE+ + Q P VR
Sbjct: 4179 NSQSPVPSPRLYKTGDLARYLPDGNIEYLGRIDNQIKIRGFRIEVGEIEAILSQHPGVRE 4238
Query: 220 CSCVW---LQTPLLLIVYF---SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAH 273
V + L+VYF +T ++ +L FLK KL + P +R++ LP +
Sbjct: 4239 NVVVAREDIPGEKRLVVYFVPQLEQTPTTDDLRIFLKEKLPQYMVPSAFVRLEFLPLTPN 4298
Query: 274 GKTSKEIL-VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSF 331
GK ++ L + + + + ++ + K L + L+ E + +FF LGG S
Sbjct: 4299 GKVDRKALPIPDSHNTQLAVSFVAPRTPVEKVLADIWANVLHLEQVGVLDNFFELGGHSL 4358
Query: 332 LAVTICNKLSLTF 344
+ + ++++ TF
Sbjct: 4359 STIRVMSQVNETF 4371
Score = 56.8 bits (131), Expect = 2e-06
Identities = 50/182 (27%), Positives = 90/182 (49%), Gaps = 10/182 (5%)
Query: 168 SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR-SCSCVWL 225
S + TGD+ + +G + Y GR+D+ +K G +I L IE+ + Q V+ S V
Sbjct: 1979 SPRLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAALSQHKDVQTSVVIVRE 2038
Query: 226 QTP-----LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
P + IV +T + +EL FLK KL + P + +++LP ++GK +
Sbjct: 2039 DIPGDKRLVSYIVLQPEQTTTVKELRSFLKEKLPDYMVPSAIAILESLPLTSNGKIDRRA 2098
Query: 281 LVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSK--SFFSLGGTSFLAVTICN 338
L + S L + +E+ AL+ +++ +L + +FF+LGG S LA + +
Sbjct: 2099 L-PAPEPSGTLSDKYVAPRTPLEEILALIWQEVLKIELVGRYDNFFTLGGHSLLATQLVS 2157
Query: 339 KL 340
++
Sbjct: 2158 RI 2159
>UniRef50_Q0VNL6 Cluster: Non-ribosomal peptide synthase; n=1;
Alcanivorax borkumensis SK2|Rep: Non-ribosomal peptide
synthase - Alcanivorax borkumensis (strain SK2 / ATCC
700651 / DSM 11573)
Length = 1361
Score = 59.7 bits (138), Expect = 3e-07
Identities = 78/296 (26%), Positives = 125/296 (42%), Gaps = 32/296 (10%)
Query: 71 PLNGIKILK-ELKHKNNKTR--IFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLS 127
PL G + L +L HK K I LYG TE + W+++ +LD + + P+G +
Sbjct: 760 PLVGGEALPAQLAHKMRKLGHPIINLYGPTETTIWSTIMKLDGDDLDAP----PIGRPIQ 815
Query: 128 ETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---ENSI---KFIDTGDI 177
T ++V E +G++ + L+R E EN + TGD+
Sbjct: 816 NTTVYVLDQEMQPVPLGAIGELYIGGVGLAKGYLHRPELTAERFIENPFGAGRLYKTGDL 875
Query: 178 GEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP---LLLIV 233
R +G + Y GR D IK G +I +ES + +C V+ + P L+
Sbjct: 876 VRWRADGVLDYLGRNDFQIKIRGFRIEAEDVESNIQRCEGVKQAVVTLRENPDGEKRLVA 935
Query: 234 YFSAETLSSQE--------LLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
+F L + E L L L + P + VDTLPTN +GK + L
Sbjct: 936 HFVPCRLDTGESAIVDTAVLRKRLAQSLPDYMIPSVFMCVDTLPTNVNGKLDRNALPEPT 995
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
++++ ++ L +L AL + E + SFF LGG S A + ++L
Sbjct: 996 WQASL--GYVAPRTTLETQLAALWCEIFGRERIGIHDSFFDLGGDSLTAARMVSRL 1049
>UniRef50_Q0LLG2 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1413
Score = 59.7 bits (138), Expect = 3e-07
Identities = 73/317 (23%), Positives = 130/317 (41%), Gaps = 18/317 (5%)
Query: 40 PSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEM 99
P+ F+ +++ + L+V+ +GGE ++ L R+F YG TE
Sbjct: 673 PTAFWHELADSVAQGAVQLPECLRVVIIGGEAALPERVQGWLNVVAPNVRLFNTYGPTEA 732
Query: 100 SCWASVAEL-DLNKVTT------GDKEVPLGNCLSETELFVQPHEKNNTMGKIILASKTR 152
+ A+VAEL D N+ T G + LG+ + +F +G + +
Sbjct: 733 TVVATVAELSDPNQPITIGRPLAGVQAAILGS--DQRPIFAGDVGDLYLLGNGLATGYYQ 790
Query: 153 KCIL--LNRKNGNKEENSIKFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIEST 210
+ L LN ++ ++ + TGD + G + + GR DD K G ++ IES
Sbjct: 791 RPDLDALNFGQLSQLPHAPRAYRTGDRVRLFAGQLQFVGRSDDEFKISGQRVTPAEIESV 850
Query: 211 VMQCPRVRSCSCVWLQ-----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRV 265
++ VR + + Q L V S +LS EL + L P + V
Sbjct: 851 FLRHTAVREVAVIGQQLGNASKRLFAAVVVSDASLSVAELRNHASQHLPAAVIPAAITIV 910
Query: 266 DTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFS 325
+ LP ++ GK ++ + + ++ N L +++ A V + D FF
Sbjct: 911 ERLPRSSAGKIDRKAVAALAPAPVMVNAAINDTPALIRQVWAEVLGQTEFND--EADFFG 968
Query: 326 LGGTSFLAVTICNKLSL 342
LGG S + + N+L +
Sbjct: 969 LGGQSLQTIQVANRLGM 985
>UniRef50_A3YFF6 Cluster: Amino acid adenylation; n=2; Bacteria|Rep:
Amino acid adenylation - Marinomonas sp. MED121
Length = 4075
Score = 59.7 bits (138), Expect = 3e-07
Identities = 55/187 (29%), Positives = 87/187 (46%), Gaps = 11/187 (5%)
Query: 165 EENSIKFIDTGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
E++ + TGD + E R G + + GR+DD +K G +I L IE T+ P V S +
Sbjct: 2042 EKHPFRLYKTGDLVKENRAGQLSFEGRIDDQVKLRGFRIELGEIEKTLETHPHVISAKVL 2101
Query: 224 WLQ--TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVI-----RVDTLPTNAHGKT 276
Q + + T Q LL L +L K PD ++ +D P A+GK
Sbjct: 2102 VTQALNKQKQLTAYLIHTADYQALLTELSHQLSSKL-PDYMVPQAWAALDAWPLTANGKL 2160
Query: 277 SKEILVNIYKKSNILQNVENI-KSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAV 334
++ L Y + Q + + K+ L K + L L E+L + +FF+LGG S +A+
Sbjct: 2161 ARAELPIAYPIAAGAQVQDRLPKTPLEKAMLDLYKSLLKQENLNLNDNFFALGGDSIIAM 2220
Query: 335 TICNKLS 341
+ K S
Sbjct: 2221 QLVAKAS 2227
>UniRef50_A2C8M5 Cluster: Putative uncharacterized protein; n=1;
Prochlorococcus marinus str. MIT 9303|Rep: Putative
uncharacterized protein - Prochlorococcus marinus
(strain MIT 9303)
Length = 2199
Score = 59.7 bits (138), Expect = 3e-07
Identities = 94/410 (22%), Positives = 165/410 (40%), Gaps = 42/410 (10%)
Query: 1 MVEILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARS 60
++EI A G++L+IAP E N ++ + H+ L R
Sbjct: 415 ILEISSALARGSTLVIAPS-------EIRSNPEALFEFLEQEGITHAFIPPAMLRLLPRR 467
Query: 61 TLKVLA---LGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGD 117
L L +GGE + + + + TR++ +YG TE + S A+L ++++ D
Sbjct: 468 KLPALTDIYVGGEASDDLTV----SFWSRATRLWNVYGPTETTVICS-AKLMTSQLSATD 522
Query: 118 KEVPL-GNCLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEE------NSIK 170
PL G + + ++P +G+I +A LNR E +
Sbjct: 523 LGGPLPGYSMFVLDQKLEPVPPG-IIGEIYIAGNAVSRGYLNRSTTTAERFFRNPFGEGR 581
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP- 228
TGD+ +G + Y GR D +K G +I L +EST+ V + P
Sbjct: 582 LYRTGDLARHFPSGELEYLGRNDFQVKIRGFRIELGEVESTIADVNGVTGVFVTVIDEPS 641
Query: 229 -LLLIVYFSA--ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL---- 281
L+ +F+ E + L + +L P +I+VDT P N GK + L
Sbjct: 642 GKTLVAWFTTNPEGPEATSLRKTISEQLTHYMVPTYLIKVDTFPVNISGKIDRSRLPMPE 701
Query: 282 -VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKL 340
+ +S L +E+ ++ E+ + + + + +FF LGG S A C+K+
Sbjct: 702 NIKSEHESEPLTGLESKVQLIWSEILEIPKERIKLD----SNFFHLGGHSLNAAIACHKI 757
Query: 341 SLTFPEVGKHILPHLLSHNKSIGDVLKTITQD--TNCLENKFKKSIKRNR 388
+ E+ + + P L N + D ++ TN LE + + R
Sbjct: 758 A---AELEQGLSPKTLFENPVLKDFSGCLSNQSKTNQLEPLIATGLTKTR 804
Score = 59.3 bits (137), Expect = 4e-07
Identities = 71/291 (24%), Positives = 134/291 (46%), Gaps = 24/291 (8%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S L+ + GGE ++ KT +++LYG TE + S + L
Sbjct: 1499 SKLRFMGFGGEAID----TSTASFWAEKTCLYSLYGPTETTVMCSGGRI-LPGANPRIVG 1553
Query: 120 VPL-GNCLSETELFVQPHEKNNTMGKIILASKTRKCIL------LNRKNGNKE--ENSIK 170
PL G ++ + +QP +G+++++ T + L LNR + + + +
Sbjct: 1554 KPLMGYSINLRDQQLQPVPLG-AIGELVISGGTARGYLNRYDLTLNRFRIDPDGVDPYQR 1612
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV--WLQT 227
+GD+G + +GT+ + GR DD IK G++I L IE+++ P V + + +
Sbjct: 1613 VYLSGDLGRFLPDGTIEFLGRNDDQIKLRGYRIELGEIEASMQSAPGVTNATAMVRGEND 1672
Query: 228 PLLLIVYFSA-ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
+LI Y + E L E+ + +L P + I+++ +P N +GK + L ++
Sbjct: 1673 NRMLIGYLTGNEGLDIDEVRQHCQEQLPGYMVPSRFIKLENMPLNPNGKLDRNALPDV-- 1730
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTI 336
+ + E K L +++ A+ L+ +++ K FF LGG S LA +
Sbjct: 1731 --SFVSTSEPPKVGLEQKVAAVWQDLLHLKNIGRKDDFFHLGGNSLLAARL 1779
>UniRef50_Q2VQ12 Cluster: Nonribosomal peptide synthetase F; n=1;
Brevibacillus texasporus|Rep: Nonribosomal peptide
synthetase F - Brevibacillus texasporus
Length = 2491
Score = 59.3 bits (137), Expect = 4e-07
Identities = 82/358 (22%), Positives = 151/358 (42%), Gaps = 25/358 (6%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKI-LCARST 61
+I + +GA+L++ P EV+ + + ++ Q F S N ++ + +
Sbjct: 1689 DIFSSLLHGATLVLVPK--EVILNPTDLITLIREQQITVSFMTTSLFNALVELDVSSFQN 1746
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
++ +A GGE + + K L N R+ YG TE + +A+ +D G +P
Sbjct: 1747 MRKIAFGGEKASFKHVEKALDFLGNG-RLVNGYGPTETTVFATTYTVDERIKEWGI--IP 1803
Query: 122 LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---ENSIK---- 170
+G L T + + + +G++ ++ + LN E EN +
Sbjct: 1804 IGRPLHNTTVHILSADDKLQPIGVIGELCVSGEGLARGYLNLPELTMERFVENPFRPGER 1863
Query: 171 FIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL---Q 226
TGD+ + +G + Y GR D+ +K GH+I L IE+ +++ P + + Q
Sbjct: 1864 MYRTGDLARWLPDGVLEYVGRKDEQVKIRGHRIELSEIETRILEHPAISETVLLAKRNEQ 1923
Query: 227 TPLLLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIY 285
L Y A + QEL ++ L E P I +D LP ++GK K L
Sbjct: 1924 GSSYLCAYIVAHGQWNIQELRKHVRDVLPEHMVPSYFIGLDKLPLTSNGKVDKRALPEPE 1983
Query: 286 KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ---SKSFFSLGGTSFLAVTICNKL 340
+ + + ++ K+L +V + L E + + + F LGG S + I K+
Sbjct: 1984 GSLQLTREIVAPRNESEKQLVEIVAEVLGLEASEISITDNLFELGGHSLTILRILAKV 2041
Score = 48.8 bits (111), Expect = 5e-04
Identities = 47/173 (27%), Positives = 82/173 (47%), Gaps = 8/173 (4%)
Query: 174 TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL---QTPL 229
TGD+ R +G++ Y GR+D+ +K G++I L IE+ +++ P + V Q
Sbjct: 832 TGDLVRWRIDGSIEYLGRIDEQVKIRGYRIELGEIETKLLEHPSISEALVVARNDEQGYT 891
Query: 230 LLIVYFSAE-TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKS 288
L Y A S L + L L E P ++ V+ +P A+GK K L + +
Sbjct: 892 YLCAYVVATGAWSVSSLREHLIETLPEYMIPAYMMEVEKMPLTANGKIDKRAL-PVPDRQ 950
Query: 289 NILQNVENIKSYLFKELKALVNKDLNYEDLQSKS-FFSLGGTSFLAVTICNKL 340
+ + V + ++L L + L E + +K FF LGG S A+ + +++
Sbjct: 951 RMNEYVAP-ATETEEKLVLLFQEILGLERIGTKDHFFELGGHSLKAMMLVSRM 1002
>UniRef50_A5MZS0 Cluster: Predicted nonribosomal peptide synthetase;
n=1; Clostridium kluyveri DSM 555|Rep: Predicted
nonribosomal peptide synthetase - Clostridium kluyveri
DSM 555
Length = 1536
Score = 59.3 bits (137), Expect = 4e-07
Identities = 74/348 (21%), Positives = 151/348 (43%), Gaps = 25/348 (7%)
Query: 78 LKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE---VPLGNCLSETELFVQ 134
L+ L +K R F T ++ + + DKE +P+G +S ++++
Sbjct: 806 LRFLLTGGDKLRFFKPCNYTLVNNYGPTENTVVTTSVVVDKEHYNIPIGKPISNIQIYIL 865
Query: 135 PHEKN----NTMGKIILASKTRKCILLNRKNGNKEE---NSI----KFIDTGDIGE-IRN 182
T G+I ++ + LNRK +E+ N + TGD+ +
Sbjct: 866 DRYNRIQPIGTQGEICISGRGLARGYLNRKKLTEEKFVKNPFMIGERMYKTGDLARWTSD 925
Query: 183 GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV----WLQTPLLLIVYFSAE 238
G + + GR+D +K ++I L IE+ +++ ++ + + + L Y S
Sbjct: 926 GNIEFLGRMDQQVKISAYRIELAEIENRLLKYEFIKDVVVIDREDFNKNKYLCAYYVSDM 985
Query: 239 TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIK 298
L ++ +L +L + P I++D +P +GK ++++L + S++ +
Sbjct: 986 ELYINDIKYYLSVQLPDYMIPAFFIKIDKIPLTINGKVNRKVLPEPDQISSMDIKYIPPR 1045
Query: 299 SYLFKELKALVNKDLNYEDLQS-KSFFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLS 357
+ + K + + + L + + +FF LGG S AV + +K+S+ F E+ + L +
Sbjct: 1046 NEMEKRMVEVWEEILGIDKVGILDNFFDLGGNSLKAVRVISKMSMDF-EIEINDLFQFQT 1104
Query: 358 HNKSIGDVLKTITQDTNCLENKFKKSI---KRNRSTSSHGENSISYKK 402
+K ++L +E K SI K +R+ S + + YKK
Sbjct: 1105 ISKLSENILYKKDNLKKIIEG-IKSSIGEKKEDRNYSQYEDKIYRYKK 1151
>UniRef50_A3IZW4 Cluster: Non-ribosomal peptide synthase; n=2;
Cyanothece sp. CCY 0110|Rep: Non-ribosomal peptide
synthase - Cyanothece sp. CCY 0110
Length = 1294
Score = 59.3 bits (137), Expect = 4e-07
Identities = 74/305 (24%), Positives = 135/305 (44%), Gaps = 27/305 (8%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTE---MSCWASVAELDLNKVTTGDK 118
+K L GGE L+ + K L+ + T++ YG TE +C S+ +KV++
Sbjct: 981 VKELLTGGEALSVHHVKKALQALPS-TQLINGYGPTENTTFTCCYSIPSFLESKVSS--- 1036
Query: 119 EVPLGNCLSETELFV-QPHEKN---NTMGKIILASKTRKCILLNRKNGNKEE------NS 168
+ +G ++ T++++ P+ + G++ + LNR + E+ +
Sbjct: 1037 -ILIGRPINNTQIYILDPNLQPVPVGVPGELHIGGDGLARGYLNRPDLTAEKFIPNPFGT 1095
Query: 169 IKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT 227
K TGD+ R +G + Y GR+D +K G +I L IE+ + P +R + +
Sbjct: 1096 GKLYKTGDLCRYRRDGNIEYIGRIDHQVKIRGFRIELGEIETQLSNHPEIRESVVIARED 1155
Query: 228 P---LLLIVYFSAETLS----SQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
L+ Y ++ +S +Q L D LK +L + P + ++ LP +GK +
Sbjct: 1156 APGNKQLVAYLVSDEMSQSSVTQTLRDCLKEQLPDYMIPSAFVLLEKLPLTPNGKIDRRA 1215
Query: 281 LVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNK 339
L +N ++ + L + L E + K +FF LGG S LA I ++
Sbjct: 1216 LPAPDSNRRGQENYIAPQTPTQELLANIWQTILKIEKISLKDNFFELGGHSLLATQIISR 1275
Query: 340 LSLTF 344
+ TF
Sbjct: 1276 VRETF 1280
>UniRef50_A3I9A7 Cluster: Peptide synthetase; n=1; Bacillus sp.
B14905|Rep: Peptide synthetase - Bacillus sp. B14905
Length = 1055
Score = 59.3 bits (137), Expect = 4e-07
Identities = 73/331 (22%), Positives = 136/331 (41%), Gaps = 28/331 (8%)
Query: 38 TTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVT 97
T P+ FF ++ TL+ L++GGE L + K + T I +YG T
Sbjct: 296 TVPNAFFTQLATHLPIDYRDKLMTLQYLSVGGEALLPAIVQKWQEKFGYSTEIINVYGPT 355
Query: 98 EMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRK 153
E + S ++ +++T +P+G ++ E++V ++ + G++ +A
Sbjct: 356 ECTVLTSYFKIK-SQLTDMQSSIPIGRPIANYEMYVVNKDEQLCPVHVTGELCIAGAGLA 414
Query: 154 CILLNRKNGNKE-------ENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLH 205
L++ E + K TGD+ + +G + + GR D IK G +I L
Sbjct: 415 AGYLHQPEKTAEAFVPHLFKPDQKMYRTGDLVRLLPSGVIEFVGRKDSQIKVRGFRIELG 474
Query: 206 SIESTVMQCPRVRSCSCV---WLQTPLLLIVYFSAET---LSSQELLDFLKCKLDEKYWP 259
IE+ + P ++ + L Y++A L Q L D+L L + P
Sbjct: 475 EIETVLSNHPIIQESVVIAKKMSDGQNHLFAYYTAANGIQLEEQVLRDYLNNLLPDYMVP 534
Query: 260 DKVIRVDTLPTNAHGKTSKEILVNI---YKKSNILQNVENIKSYLFKEL--KALVNKDLN 314
++ I + +P + GK ++ L + +S++ EN +L L N +
Sbjct: 535 ERFIELLEMPLSPTGKIDRKQLATLDESLSRSHLYVAPENDTQHLLANAWEYVLGNSPIG 594
Query: 315 YEDLQSKSFFSLGGTSFLAVTICNKLSLTFP 345
D +FF +GG S + I ++ P
Sbjct: 595 IHD----NFFHIGGHSLKVLEILVQVKKHIP 621
>UniRef50_A0ZF80 Cluster: Peptide synthetase; n=3; Nostocaceae|Rep:
Peptide synthetase - Nodularia spumigena CCY 9414
Length = 1075
Score = 59.3 bits (137), Expect = 4e-07
Identities = 50/184 (27%), Positives = 91/184 (49%), Gaps = 12/184 (6%)
Query: 174 TGD-IGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP---L 229
TGD + + +G + + GR+D+ +K G +I L IE+ ++Q P ++ + +
Sbjct: 841 TGDLVRRLPDGNLEFIGRIDNQVKIRGFRIELAEIEAVLIQYPDIKQAVVMAREDEPGQK 900
Query: 230 LLIVYFSAET--LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL-VNIYK 286
LL+ Y A+ L+ L +FLK KL + P + ++ LP +GK ++ L + +
Sbjct: 901 LLVAYLVAQNNVLTPSSLRNFLKSKLPDYMIPAAFVFLENLPLTPNGKINRRALPIPDHT 960
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL----S 341
+ N+ + + KEL + + L + + + +FF LGG S LA ++L S
Sbjct: 961 QRNLEIDFVPPSTDTEKELADIWTEVLKLKQVGINDNFFELGGHSLLATQAISRLREVFS 1020
Query: 342 LTFP 345
L FP
Sbjct: 1021 LDFP 1024
>UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3;
Bacteria|Rep: Non-ribosomal peptide synthetase - Erwinia
carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 7523
Score = 58.8 bits (136), Expect = 5e-07
Identities = 65/275 (23%), Positives = 116/275 (42%), Gaps = 28/275 (10%)
Query: 88 TRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFV-----QPHEKNNTM 142
TR +YG TE + A+ +D + +G L+ TE+++ QP T
Sbjct: 766 TRFINVYGPTECTVDATACPID-----SSQSAPTIGRPLTNTEVYILGTQGQPVPIGVT- 819
Query: 143 GKIILASKTRKCILLNRKNGNKE---------ENSIKFIDTGDIGEIRN-GTVFYRGRVD 192
G+I + LNR + E E + TGD+G R+ G++ Y GR D
Sbjct: 820 GEIYIGGAGVARGYLNRPDLTAERFITNPFVDEQEARLYKTGDLGYWRHDGSITYLGRND 879
Query: 193 DTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT---PLLLIVYFSAETLSSQELLDF- 248
+K G ++ L IE+ ++Q P ++ + + L+ YF A+ + D
Sbjct: 880 FQVKLRGFRLELGEIETLLIQYPGIQEAVVILREDIPGDKRLVAYFQAQPDTQPTPADLR 939
Query: 249 --LKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELK 306
L +L E P + +D P +GK ++ L K + + ++ E + + L
Sbjct: 940 LQLSQRLAEYMIPSAFVALDAFPLTPNGKLDRKALPEPDKSAMVTRHYEAPQGEMETMLA 999
Query: 307 ALVNKDLNYEDLQSKS-FFSLGGTSFLAVTICNKL 340
++ L + + FF LGG S + V++ +L
Sbjct: 1000 SIWQTLLGIDHVSRYDHFFELGGQSLMVVSLIEQL 1034
Score = 58.8 bits (136), Expect = 5e-07
Identities = 72/300 (24%), Positives = 121/300 (40%), Gaps = 29/300 (9%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
LK L LGGE ++ K + R+F YG TE++ A+++ D + T P
Sbjct: 3958 LKTLILGGEACTAAQV----KRWASGRRVFNAYGPTEITVCATLSCCDASHNGTP----P 4009
Query: 122 LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE---------NS 168
+G ++ T++++ +K G+I + LNR E
Sbjct: 4010 IGRPIANTQIYILDEQKQPVPLGVAGEIYIGGAGVARGYLNRPELTAERFIADPFTDTPD 4069
Query: 169 IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT 227
+ TGD+G + NG + Y GR D IK G +I L IE+ ++QC V + +
Sbjct: 4070 ARLYKTGDLGRWLPNGDIDYLGRNDFQIKLRGFRIELGEIETHLIQCSGVGEAVVIARED 4129
Query: 228 ---PLLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
L+ Y + L +L L L E P + +D P ++GK + L
Sbjct: 4130 STGDARLVAYLCPQPGAELHPTDLRQQLSRHLAEYMVPSAFVVLDVFPLTSNGKLDRNAL 4189
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + + E + L L + L + + + FF LGG S + V + +L
Sbjct: 4190 PAPGQTAVARHDYEAPQGELEIALAQIWQDLLGLDRVGRHDQFFELGGHSLIIVRLIERL 4249
Score = 55.6 bits (128), Expect = 5e-06
Identities = 48/176 (27%), Positives = 82/176 (46%), Gaps = 8/176 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ-TP--L 229
TGD+ + +G + Y GR D IK G +I IES +++CP V+ + + +P
Sbjct: 5150 TGDLARWLPDGNIDYLGRNDFQIKVRGFRIEAGEIESRLLRCPGVQDAVVIAREDSPGDT 5209
Query: 230 LLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L+ Y A L L L L + P + +D LP +GK ++ L +
Sbjct: 5210 RLVAYLCARPDAELHPAALRQQLAASLADYMIPSAFVTLDALPLTPNGKLDRKALPAPDQ 5269
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLS 341
+ ++ E + + L AL + L + + + FF+LGG S LAV + N+++
Sbjct: 5270 TAFATRDYEAPQGGIETALAALWQELLGLDRVGRHDQFFALGGHSLLAVQLLNRMN 5325
Score = 53.6 bits (123), Expect = 2e-05
Identities = 89/369 (24%), Positives = 152/369 (41%), Gaps = 40/369 (10%)
Query: 1 MVEILLACTNGASLLIAPDL----TEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKIL 56
++EI L NGA L++A + L ++V+F Q TPS + ++ +
Sbjct: 7109 ILEIFLPLLNGARLILATQAQAADAQQLAMLIERHAVSFMQATPSTW----RMLVELRDF 7164
Query: 57 CARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTG 116
K L GGE L + L K T ++ LYG TE + W++ LN +TT
Sbjct: 7165 ALPPGFKALC-GGEALPE-NLATALLQK--VTTLWNLYGPTETTIWST-----LNGLTTP 7215
Query: 117 DKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE------ 166
+ G+ ++ T++++ + G+I +A L R + E
Sbjct: 7216 TPYI--GHPIANTQIYILDAQGRVVPLGVAGEIHIAGAGVVRGYLGRPDLTAERFITDPF 7273
Query: 167 ---NSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSC 222
+ TGD+G + +GT+ Y GR D +K G +I L IE+ + +C V
Sbjct: 7274 SGAPEARMYKTGDLGRWLPDGTLEYLGRNDFQVKVRGFRIELGEIETRLARCHGVHDAVV 7333
Query: 223 VWLQ-TP--LLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
+ + +P L+ Y A+ L +L L + E P + +D P +GK
Sbjct: 7334 IAREDSPGDKRLVAYLLAQPDTVLEPADLRQRLSEGVAEYMIPSAFVTLDAFPLTPNGKL 7393
Query: 277 SKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVT 335
++ L + + + E + L L + L E + + FF LGG S LAV
Sbjct: 7394 DRKALPAPDQSAMATRGYEAPQGDLEHALAQIWQTLLGVERVGRHDHFFELGGHSLLAVQ 7453
Query: 336 ICNKLSLTF 344
+ ++ F
Sbjct: 7454 LNARIRAEF 7462
Score = 50.0 bits (114), Expect = 2e-04
Identities = 47/175 (26%), Positives = 80/175 (45%), Gaps = 8/175 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ-TP--L 229
TGD+ + +G++ Y GR D +K G +I L IE+ +MQCP V+ V + +P
Sbjct: 6208 TGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVAREDSPGDT 6267
Query: 230 LLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L+ Y + T +L L L E P + +D P +GK ++ L +
Sbjct: 6268 RLVAYLCPQPGVTPDPADLRQQLGQHLAEYMVPGAFVTLDAFPLTPNGKLDRKALPAPDQ 6327
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ ++ E + + L A+ L + + FF+LGG S L V++ +L
Sbjct: 6328 SAVATRDYEAPQGEVETALAAVWQDLLGLTRVGRHDHFFALGGHSLLIVSLIERL 6382
Score = 48.8 bits (111), Expect = 5e-04
Identities = 46/175 (26%), Positives = 80/175 (45%), Gaps = 8/175 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ-TP--L 229
TGD+ + +G++ Y GR D +K G +I L IE+ +MQCP V+ V + +P
Sbjct: 2999 TGDLARWLPDGSLEYLGRNDFQVKLRGFRIELGEIEARLMQCPGVQEAVVVAREDSPGDT 3058
Query: 230 LLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L+ Y + T +L L L E P + +D P +GK ++ L +
Sbjct: 3059 RLVAYLCPQLGVTPDPADLRQQLGQHLAEYMVPGAFVTLDAFPLTPNGKLDRKALPAPDQ 3118
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ ++ E + + L A+ L + + FF+LGG S + V++ +L
Sbjct: 3119 SAVATRDYEAPQGEVETALAAVWQDLLGLTRVGRHDHFFALGGHSLMIVSLIEQL 3173
Score = 48.0 bits (109), Expect = 0.001
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 8/178 (4%)
Query: 165 EENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
+ + + TGD+G + +G + Y GR D IK G +I IE+ +M P VR +
Sbjct: 1931 DSENAQIYKTGDLGRWLPDGNIEYLGRNDFQIKVRGFRIEPGEIEARLMAYPGVREALVI 1990
Query: 224 WLQ-TP--LLLIVYFSAET---LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTS 277
+ +P + L+ Y A+ L L L L E P + +D P +GK
Sbjct: 1991 AREDSPGDIRLVAYLIAQPGSELIPSVLRKALALHLAEYMVPSAFVTLDAFPLTPNGKLD 2050
Query: 278 KEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAV 334
++ L + + + + E L L + L E + + FF LGG S LAV
Sbjct: 2051 RKALPVPEQSAIVSRGYEAPVGELEMALTEIWQNLLGLERVGRHDHFFELGGHSILAV 2108
>UniRef50_Q2Y7Z5 Cluster: Amino acid adenylation; n=2; Nitrosospira
multiformis ATCC 25196|Rep: Amino acid adenylation -
Nitrosospira multiformis (strain ATCC 25196 / NCIMB
11849)
Length = 4037
Score = 58.8 bits (136), Expect = 5e-07
Identities = 84/345 (24%), Positives = 141/345 (40%), Gaps = 39/345 (11%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
+TL+ + GE L ++ K++ K +F LYG TE A++ V D
Sbjct: 2311 ATLRRIICSGEALQA-EVQKQVFRKLPGVGLFNLYGPTE----AAIDVTQWECVDDRDNS 2365
Query: 120 VPLGNCLSETELFVQPHEKNNT----MGKIILASKTRKCILLNRKNGNKE--------EN 167
VP+G +S + ++ N G++ L LNR + E
Sbjct: 2366 VPIGKPISGLQAYILDVHLNQVPQGVAGELYLGGIGLARGYLNRGGLTADRFIADPFDET 2425
Query: 168 SIKFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ 226
+ TGD+ R+ G + Y GR+D +K G +I L IE+ ++ P VR V +
Sbjct: 2426 GGRLYRTGDLARWRSDGQIEYLGRLDHQVKIRGFRIELGEIETQLLAQPEVREAVVVARE 2485
Query: 227 -----TP---LLLIVYFSAET---LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGK 275
P LI Y SA L + L + L L + P ++ +++LP N GK
Sbjct: 2486 GSNASNPTGGARLIAYVSAHATTDLDAARLREALARTLPDYMLPSMIVVLESLPLNPSGK 2545
Query: 276 TSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAV 334
++ L + ++ E + + L + + L + + +FF LGG S L++
Sbjct: 2546 VDRKALPE--PEFTHTEHYEAPQGEAEEVLAGIWGQVLGVAQVGRHDNFFELGGDSILSL 2603
Query: 335 TICNKLSLTFPEVGKHILPHLLSHNK---SIGDVLKTITQDTNCL 376
I + VG I P L + S+ +V +TI + L
Sbjct: 2604 QIVTRAR----RVGWKITPRQLFERQTIASLAEVAETIQETVAAL 2644
Score = 49.2 bits (112), Expect = 4e-04
Identities = 48/188 (25%), Positives = 84/188 (44%), Gaps = 15/188 (7%)
Query: 165 EENSIKFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV 223
+E + TGD+ R+ G + Y GR+D +K G +I L IE+ ++ P VR V
Sbjct: 888 DETGGRLYRTGDLARWRSDGQIEYLGRLDHQVKIRGFRIELGEIETQLLAQPEVREAVVV 947
Query: 224 WLQ-----TP---LLLIVYFSAET---LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNA 272
+ P LI Y SA L + L + L L + P ++ +++LP N
Sbjct: 948 AREGSSASNPTGGARLIAYVSAHATTDLDAARLREALARTLPDYMLPSMIVVLESLPLNP 1007
Query: 273 HGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSF 331
GK ++ L + ++ E + + L + + L ++ + +FF LGG S
Sbjct: 1008 SGKVDRKALPE--PEFTHTEHYEAPQGEAEEVLAGIWGQVLGVAEVGRHDNFFELGGDSI 1065
Query: 332 LAVTICNK 339
L++ I +
Sbjct: 1066 LSLQIVTR 1073
>UniRef50_Q9K5M1 Cluster: Peptide synthetase; n=8; Bacteria|Rep:
Peptide synthetase - Anabaena circinalis 90
Length = 5060
Score = 58.8 bits (136), Expect = 5e-07
Identities = 52/194 (26%), Positives = 91/194 (46%), Gaps = 11/194 (5%)
Query: 160 KNGNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR 218
+N +NS K TGD+ + +G + Y GR+D+ +K G +I L IE+ + Q V+
Sbjct: 847 RNAKDVQNS-KLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEAVLSQLGDVQ 905
Query: 219 SCSCVWLQTPLL----LIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTN 271
+ SCV ++ + L+ Y + T + EL FLK KL E P+ + +++LP
Sbjct: 906 A-SCVIVREDITGDKRLVAYIVPQKEVTPTVTELRQFLKAKLPEYMVPNAFVILESLPLT 964
Query: 272 AHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTS 330
+GK L S + ++ + + L + + L E + +FF+ GG S
Sbjct: 965 PNGKIDHRALPTPDLHSELKHKYVAPRTPVEEILAQIWAQVLKVEQVGIEDNFFTSGGHS 1024
Query: 331 FLAVTICNKLSLTF 344
LA + + + F
Sbjct: 1025 LLATQLVSHIRNIF 1038
Score = 45.6 bits (103), Expect = 0.005
Identities = 43/170 (25%), Positives = 80/170 (47%), Gaps = 20/170 (11%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
+TL+ + + GE ++++K+ N F YG TE S A++A K + ++
Sbjct: 4303 TTLQTIIVAGEAC-AVELIKQWSAGRN---FFNAYGPTEGSVCATLA-----KCSALTQK 4353
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE------NSI 169
+PL ++ ++++ + G++ +A LNR +E+
Sbjct: 4354 LPLVGPIANVQVYILDSQLQPVPIGVPGELHIAGVGVARGYLNRPELTQEKFISNPFGPS 4413
Query: 170 KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR 218
K TGD+G + +GT+ Y GR+D+ +K G +I L IE+ Q P V+
Sbjct: 4414 KLYKTGDLGRYLADGTIEYLGRIDNQVKIRGFRIELGEIEAVASQHPLVQ 4463
Score = 44.8 bits (101), Expect = 0.009
Identities = 53/205 (25%), Positives = 89/205 (43%), Gaps = 26/205 (12%)
Query: 33 VTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPL--NGIKILKELKHKNNKTRI 90
VT TPS F Q ++ L+++ GGE L N ++ + +H + ++
Sbjct: 2858 VTILNQTPSAFRQLIPAE-QSIATVGDLNLRLVIFGGETLELNSLQPWFD-RHGDQSPQL 2915
Query: 91 FTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFV-----QPHE-------- 137
+YG+TE + V L+K K +G + + +++V QP
Sbjct: 2916 VNMYGITETT--VHVTYRPLSKADLHGKASVIGRPIGDLQVYVLDEHLQPVPIGVAGEMY 2973
Query: 138 ---KNNTMGKIILASKTRKCILLNRKNGNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDD 193
T G + A T + + N NGN E+ K +GD+ + NG + Y GR+D+
Sbjct: 2974 VGGAGVTRGYLNRAELTAQRFISNPFNGNSEQLLYK---SGDLARYLPNGELEYLGRIDN 3030
Query: 194 TIKRFGHKINLHSIESTVMQCPRVR 218
+K G +I L IE+ + Q VR
Sbjct: 3031 QVKIRGFRIELGEIEAALSQLREVR 3055
>UniRef50_Q4CA71 Cluster: Amino acid adenylation; n=1; Crocosphaera
watsonii WH 8501|Rep: Amino acid adenylation -
Crocosphaera watsonii
Length = 1049
Score = 58.8 bits (136), Expect = 5e-07
Identities = 93/371 (25%), Positives = 157/371 (42%), Gaps = 49/371 (13%)
Query: 3 EILLACTNGASLLIA-PD------LTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKI 55
E L NGA L+IA PD L E N +V F + F + + N
Sbjct: 652 EFLWTLLNGACLVIAKPDGHQDSAYLASLIIEQNITTVHFVPSMLQVFLEEQKASQCN-- 709
Query: 56 LCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVT- 114
+LK + GE L+ L+ + K + LYG TE A +D+ T
Sbjct: 710 -----SLKRVICSGEALS--VDLRNRFFQTIKAELNNLYGPTE-------AAIDVTACTC 755
Query: 115 -TGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE--- 166
T D VP+G + +++V + +G++ L + LN+ + E
Sbjct: 756 QTDDLSVPIGLPIDNIQVYVLNAQLQLLPVGVVGELYLGGEGLARGYLNKPDLTAENFVP 815
Query: 167 NSIK----FIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
N K TGD + +G V Y GR+D+ +K G ++ L IE+ + Q P + +C
Sbjct: 816 NPFKAGARLYRTGDFVRYQEDGNVEYVGRIDNQVKIRGVRLELGEIEAILSQHPDIIACV 875
Query: 222 CVWLQ-TP----LLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKT 276
+ + P LL + S S+EL FL ++ P I +++ P +GK
Sbjct: 876 VLAKEFAPGDRRLLAYIQTSQTEDISEELRQFLGERIPNYGIPSVFITLESFPLTNNGKL 935
Query: 277 SKEILV--NIYKKSNILQNVENIKSYLFKELKALVNKD-LNYEDLQSKSFFSLGGTSFLA 333
+ + L+ N K I+ ++ + + K ++ D L+ +D +FF LGG S +A
Sbjct: 936 NTKALLALNYSSKKEIMSPRNETETAIMEIWKEILKVDNLSIDD----NFFELGGNSLIA 991
Query: 334 VTICNKLSLTF 344
+ ++L +F
Sbjct: 992 TRVNSRLRQSF 1002
>UniRef50_Q3WCM4 Cluster: AMP-dependent synthetase and ligase; n=1;
Frankia sp. EAN1pec|Rep: AMP-dependent synthetase and
ligase - Frankia sp. EAN1pec
Length = 511
Score = 58.8 bits (136), Expect = 5e-07
Identities = 45/131 (34%), Positives = 61/131 (46%), Gaps = 5/131 (3%)
Query: 156 LLNRKNGNKEENSIKFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQC 214
LL + G ++ +I T D+ I + G +F GR DD I R G KI IE + Q
Sbjct: 369 LLEARGGQLSDDGGAWIRTTDLASIDDDGFLFIHGRADDAISRGGFKIPPSVIEEALAQH 428
Query: 215 PRVRSCSCVWLQTPLLLIVYFSAETLSS----QELLDFLKCKLDEKYWPDKVIRVDTLPT 270
P V S V L P L V A TLS+ EL++FL +L P + VD LP
Sbjct: 429 PAVDEASAVGLADPRLGEVPVVAVTLSAPATEAELMEFLSARLTRYQRPVDLAIVDALPR 488
Query: 271 NAHGKTSKEIL 281
K S+ ++
Sbjct: 489 TPSLKVSRALV 499
>UniRef50_Q0W980 Cluster: Non-ribosomal peptide synthetase; n=2;
Cyanobacteria|Rep: Non-ribosomal peptide synthetase -
Planktothrix agardhii NIVA-CYA 126
Length = 1598
Score = 58.8 bits (136), Expect = 5e-07
Identities = 62/222 (27%), Positives = 101/222 (45%), Gaps = 16/222 (7%)
Query: 160 KNGNKEE--NSIKFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPR 216
K GN E + + TGD+ N G + + GR+DD +K G +I L +E+ + Q P+
Sbjct: 902 KQGNSEVLLPTDRLYKTGDLVRYGNDGQIEFVGRIDDQVKIRGFRIELGEVETVLNQHPQ 961
Query: 217 VRSCSCVWLQ----TPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNA 272
V+ + + L + LS EL FL+ KL + P +I +D P A
Sbjct: 962 VKEAIIIAREDQPGVKRLCAYIIGHKKLSISELRLFLQEKLPQYMIPAFLIILDAFPLTA 1021
Query: 273 HGKTSKEILVNIYKKSNILQNVENIKSYLFKE--LKALVNKDLNYEDLQ-SKSFFSLGGT 329
+GK + L + ++V NI E L A+ + L + + + +FF LGG
Sbjct: 1022 NGKIDRLALPQPALELED-EDVRNITPTTDTEKILIAIWQEILGLKKISINDNFFELGGD 1080
Query: 330 SFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQ 371
S L + I K + + G I P L +++I L T+T+
Sbjct: 1081 SILGIQIIAKAN----QAGLEITPKQLFSHQTIAQ-LATVTE 1117
>UniRef50_A7IZW2 Cluster: OciB; n=1; Planktothrix agardhii NIVA-CYA
116|Rep: OciB - Planktothrix agardhii NIVA-CYA 116
Length = 4728
Score = 58.8 bits (136), Expect = 5e-07
Identities = 55/195 (28%), Positives = 92/195 (47%), Gaps = 19/195 (9%)
Query: 163 NKEENS-IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRS- 219
NK+ N K TGD+ + +G + Y GR+D+ +K G +I L IE+ + Q V+S
Sbjct: 3001 NKDGNEPSKLYKTGDLARYLPDGNIEYLGRIDNQVKIRGFRIELGEIEALLNQNEDVQSA 3060
Query: 220 CSCVWLQTP--LLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
C P L+ Y + L+ E+ FLK KL + P+ + ++ LP +G
Sbjct: 3061 CVIAREDNPGDKRLVAYLVPQPEIILTIDEIRQFLKAKLPDYMVPNAFVILEALPLTPNG 3120
Query: 275 KTSKEIL--VNIYKKSNIL---QNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGT 329
K + L ++ + + +E + ++ E+ L K ++ ED +FF LGG
Sbjct: 3121 KIDRRALPVPDLQSQGEYIAPRNPIEEKMAQIWAEVLKL--KRVSIED----NFFELGGH 3174
Query: 330 SFLAVTICNKLSLTF 344
S LA ++L TF
Sbjct: 3175 SLLATQAISRLQETF 3189
Score = 49.2 bits (112), Expect = 4e-04
Identities = 86/392 (21%), Positives = 162/392 (41%), Gaps = 56/392 (14%)
Query: 2 VEILLACTNGASLLIAPDLTEVLFHEDNDNSVTFWQTT----PSKFFQHSNENIKNKILC 57
V+ + +C ++L+ + ED WQ T P+ ++ + L
Sbjct: 663 VQEIFSCLLSGAILVLRTEDMLRSSEDFWQYCQKWQLTVLSFPTAYWHQLVSELTPTALQ 722
Query: 58 ARSTLKVLALGGEPLNGIKILKELKHKNNKT---RIFTLYGVTEMSCWASVAELDLNKVT 114
+ +K++ +GGE + K+ + ++ N + ++F YG TE + ++ + +T
Sbjct: 723 IITNIKLIMVGGEAIQPSKVKQWHQNTVNYSPLPQLFNAYGPTEATIITTLCKFTSPTIT 782
Query: 115 TGDKEVPLGNCLSETEL-----FVQPHEKNNTMGKIILASKTRKCILLNR---------- 159
VP+G LS T++ F+QP G++ + LNR
Sbjct: 783 N----VPIGRPLSNTQVYILDAFLQPVPVG-VAGELHIGGAGLARGYLNRPELTQEKFIP 837
Query: 160 ----KNG-------NKEEN-SIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHS 206
+ G NK N S K TGD+ + +G + Y GR+D+ +K G +I L
Sbjct: 838 NPFDEEGLIPPNPINKGSNESSKLYKTGDLCRYLPDGNIEYLGRIDNQVKIRGFRIELGE 897
Query: 207 IESTVMQCPRVRSCSCVWLQTPL---LLIVYFSAE----------TLSSQELLDFLKCKL 253
IE+ + Q V++ + + L+ Y + L+ EL FLK +L
Sbjct: 898 IETILSQHSAVKTAIVIAREDETEQKRLVAYIVPQEGISNRQEQGLLAVTELRQFLKAQL 957
Query: 254 DEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFKELKALVNKDL 313
E P + +++LP ++GK + L +S + ++ + + L ++ K L
Sbjct: 958 PEYMVPSAFVILESLPLTSNGKVDRRALPAPDFQSE--EQYVAPRNPIEEILASIWVKVL 1015
Query: 314 NYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
E + +F LGG S LA + +++ F
Sbjct: 1016 KVEQVGIHDNFLELGGHSLLATQLISRIRKAF 1047
Score = 48.4 bits (110), Expect = 7e-04
Identities = 81/355 (22%), Positives = 155/355 (43%), Gaps = 36/355 (10%)
Query: 18 PDLTEVLFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPL--NGI 75
P LT+ + + S+T TP+ + + + + S+L+V+A+GG+ + +
Sbjct: 1771 PTLTDFADFIEQE-SLTLLNITPAYWHEWAIA-VSQSSATVPSSLRVVAVGGDAVLPETV 1828
Query: 76 KILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQP 135
I +E K + + +YG TE S A V +L L+ + V +G ++ T+ ++
Sbjct: 1829 NIWREWVGK--QVQCINVYGPTEASVTAIVHDL-LDSQSEKINSVLIGRPIANTKAYIL- 1884
Query: 136 HEKNNTMGKIILASKTRKC-ILLNRKNGNKEE-NSIKFID-------------TGDIGE- 179
++N I + + C + L R N+ E + KFID TGD+
Sbjct: 1885 -DQNLQPAPIGVKGELHLCGVRLARGYLNRPELTAEKFIDNPFAAAPFNRLYKTGDLARY 1943
Query: 180 IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL----LLIVYF 235
+ NG++ GR+D+ +K G +I L IE+ + Q V++ SCV ++ L L+ Y
Sbjct: 1944 LPNGSIECFGRIDNQVKIRGFRIELGEIEAILNQHLDVQT-SCVIIREDLPGQKYLVAYI 2002
Query: 236 SAETLSSQ-----ELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNI 290
+ + EL FL L P + +++LP + K + L + +
Sbjct: 2003 VISSHYERIPMISELRQFLAGNLPMYMVPQAFVFLESLPLTTNRKVDRRALPAPNLEGDR 2062
Query: 291 LQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
++ + + L + + L + +FF +GG S LA + +++ F
Sbjct: 2063 RDQYVAPRNAIEEMLLQIWTEVLKVGQVGIYDNFFEIGGHSLLATQLVSRIRSLF 2117
Score = 35.9 bits (79), Expect = 4.0
Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 166 ENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR 218
E K TGD+ + +G + Y GR+D+ +K G +I L IE+ + Q P V+
Sbjct: 4061 EQPSKLYKTGDLARYLPDGQIEYLGRIDNQVKVRGFRIELGEIEAVLGQHPLVQ 4114
>UniRef50_A6P624 Cluster: Nonribosomal peptide synthetase; n=1;
Microcystis aeruginosa|Rep: Nonribosomal peptide
synthetase - Microcystis aeruginosa
Length = 1415
Score = 58.8 bits (136), Expect = 5e-07
Identities = 46/176 (26%), Positives = 88/176 (50%), Gaps = 10/176 (5%)
Query: 170 KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ-- 226
K TGD+ + +G + + GR+DD +K G +I L IE+ + Q P V+ C Q
Sbjct: 918 KIYKTGDLARYLPDGKIEFLGRIDDQVKIRGIRIELGEIEARICQYPLVKDCVVAAYQAD 977
Query: 227 TPLLLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
T L+ Y A+ +++ ++L +L+ L P ++I +D P ++GK +++ L
Sbjct: 978 TGQHLVAYLVAQDALSINQKQLKAYLQNYLPISMIPSQIIILDAFPLTSNGKVNRKAL-P 1036
Query: 284 IYKKSNILQNVENI--KSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTI 336
I + L + +++ + L +L + L + + + FF +GG S LA+ +
Sbjct: 1037 IPAQCQTLSSEKSVIPRDNLELKLTQIWEHLLKRQPISITDDFFDMGGHSLLALQL 1092
>UniRef50_A4C4R9 Cluster: Cell surface protein; n=1; Pseudoalteromonas
tunicata D2|Rep: Cell surface protein - Pseudoalteromonas
tunicata D2
Length = 1399
Score = 58.8 bits (136), Expect = 5e-07
Identities = 73/402 (18%), Positives = 161/402 (40%), Gaps = 31/402 (7%)
Query: 367 KTITQDTNCLENKFKKSIKRNRSTSSHGENSISYKKGA---GGIRNSNTVEFVV-----Q 418
K + L N ++ S+GE +++YK G ++++ VV
Sbjct: 986 KIVNGSPEALSNANNANLTITTPDPSNGE-TLTYKLTVTDDDGATAEDSIDVVVYSPRFN 1044
Query: 419 WTFDTGKCVDASPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCV 478
W+F T +++SPA+ S +V++ GS K+ ++++ + +P++
Sbjct: 1045 WSFATAAAINSSPAIDSSGNVIF---GSDDNKLYALDSSGNKLWEFATANKITASPLIDD 1101
Query: 479 HDECVTSPCGVVGTYDGTVICFLLENCSV-IWQINVGSMIKSKATYCKGVLYIASYDGNI 537
D +G+ D + ++N +WQ + I +A + D I
Sbjct: 1102 TDNIY------IGSQDKKF--YKIDNTGTQLWQQTTANPILVEAALLASDNLLFVSDSTI 1153
Query: 538 RCIDILTSTIKETVHVSDQAISADLVLAKNEFILFGTLSGVCACLHVNTKTIIWQGSLKG 597
+D S + H S + SA + + + ++ + + + N + L
Sbjct: 1154 NVVDSSGSAVWNFTHPSTNSYSAAISSSSDNVLIISSDKYLYEFSYSNGSSGPQDSELTP 1213
Query: 598 PIFACPVLYDNDKYVIFAEVNGEIHCRTVEKGIKIWTYNGAKGNIFSSLCVKEINKFKWQ 657
I + DN YV F + +H +G ++Y + +++ I
Sbjct: 1214 AITNSSPIADNT-YVYFGASDSNVHTYGYNEGF--YSYWQSPFTTTAAVYSPAILSTNSD 1270
Query: 658 MYFGCHDNNVYSVNITNFQPSLHWKTRVSSPVYSTPTIFND----KLILAASTDGKLWVI 713
+Y G DN Y+++ + S W+ + +Y + + ND L++ S+DG L+ +
Sbjct: 1271 VYIGSTDNIFYAIDSSG---SELWRFTTNGAIYGSALLLNDGSTNNLVIFGSSDGYLYAL 1327
Query: 714 HSELGTVTAQYQLPGETFSSPIICDDHVFIGCRNDLLYSLKI 755
++ G + +++ G SSP +++++ + +Y + I
Sbjct: 1328 NAADGVLVWKFKSGGAIKSSPNFKGNNIYVTSTDGKIYCITI 1369
Score = 36.7 bits (81), Expect = 2.3
Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 4/118 (3%)
Query: 430 SPALYKSESVLYVTVGSHSGKIVVMNANTGFIQGLIKLKSRIEAPILCVHDECVTSPCGV 489
SPA+ + S +Y+ GS ++++ G I L ++D T+ +
Sbjct: 1261 SPAILSTNSDVYI--GSTDNIFYAIDSS-GSELWRFTTNGAIYGSALLLNDGS-TNNLVI 1316
Query: 490 VGTYDGTVICFLLENCSVIWQINVGSMIKSKATYCKGVLYIASYDGNIRCIDILTSTI 547
G+ DG + + ++W+ G IKS + +Y+ S DG I CI I T+
Sbjct: 1317 FGSSDGYLYALNAADGVLVWKFKSGGAIKSSPNFKGNNIYVTSTDGKIYCITISGYTL 1374
>UniRef50_Q9FDB0 Cluster: Six-domain nonribosomal peptide synthetase;
n=22; Vibrio|Rep: Six-domain nonribosomal peptide
synthetase - Vibrio cholerae
Length = 2413
Score = 58.4 bits (135), Expect = 7e-07
Identities = 61/241 (25%), Positives = 111/241 (46%), Gaps = 29/241 (12%)
Query: 61 TLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
+L+++A GG+ + I +L+ +N R+ +L G TE + W+ EL + V+ +
Sbjct: 1155 SLRLIAQGGDYIKPATIA-QLRAGSNPPRLISLGGPTETTIWSIWHELTADDVSV----I 1209
Query: 121 PLGNCLSETELFV----QPHEKNNTMGKIILASKTRKCILLNRKNGN-KEENSIKFID-- 173
P G L+ F+ Q H +G+I + L ++G K+ + + +D
Sbjct: 1210 PYGRPLAGNRYFIMDEIQRHVPQGVVGRIFTSGVNLAQGYL--EDGELKQTDFVTVLDEH 1267
Query: 174 --------TGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV- 223
TGD G R +G + + R++ +K G +++L IE + P + S V
Sbjct: 1268 GHPVRAFRTGDQGYYRADGNIIFASRINGYVKVRGVRVSLPDIEKQLQTHPALASVVVVD 1327
Query: 224 WLQT--PLLLIVYFSA---ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
+ T L FS ++ SSQ L +F K L + P + I ++ LP +A+GK +
Sbjct: 1328 YADTNGDTALAALFSVKPQQSASSQALREFAKQSLPSSHIPSRFIALEALPLSANGKVDR 1387
Query: 279 E 279
+
Sbjct: 1388 K 1388
>UniRef50_Q0LN54 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1661
Score = 58.4 bits (135), Expect = 7e-07
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 11/183 (6%)
Query: 166 ENSIKFIDTGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVW 224
E + TGD+ G + + GR D +K G +I L IE+ ++Q P + S +
Sbjct: 1434 EPGARMYRTGDLARYNQAGVLSFLGRSDQQVKIRGFRIELGEIEACLLQHPALHSVAVAV 1493
Query: 225 L----QTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
+ Q L+ + A+ +S Q L DF++ +L P + LP NA+GK ++
Sbjct: 1494 VGVAEQARLIAYLVAKAKPVSDQLLRDFVQARLPHYLQPSGYCWLSQLPLNANGKLDRQR 1553
Query: 281 L--VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTIC 337
L + ++ +N EL A + L E + +++FF LGG S LA +
Sbjct: 1554 LPIPQLQTAERLIIAPQNADQAKLAELWAAI---LQREQVGINQNFFELGGHSLLATRLV 1610
Query: 338 NKL 340
+++
Sbjct: 1611 SQI 1613
>UniRef50_A0ZEC3 Cluster: Beta-ketoacyl synthase; n=26;
Cyanobacteria|Rep: Beta-ketoacyl synthase - Nodularia
spumigena CCY 9414
Length = 2640
Score = 58.4 bits (135), Expect = 7e-07
Identities = 98/397 (24%), Positives = 168/397 (42%), Gaps = 46/397 (11%)
Query: 60 STLKVLALGGEPLNG--IKILKEL--KHKNNKTRIFTLYGVTEMSCWASV--AELDLNKV 113
S++K L GE ++ I++ EL KH+ I +G+TE SC A L +++
Sbjct: 324 SSMKFLVNAGEQVSAKTIRLFLELLAKHQLQDGVIKPAFGMTE-SCSGITWSAGLSKDEL 382
Query: 114 TTGDKEVPLGNCLSETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSIKFID 173
+ + LG + + + E + I + + C + N E N F D
Sbjct: 383 QQENSFISLGKPIPGATIRIIDQENHVLPENEIGRLQIKGCSVTEGYYHNPELNQEVFQD 442
Query: 174 -----TGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRV----RSCSCVW 224
TGD+G + NG +F GR I G H IE+T+ + V + V+
Sbjct: 443 GGWFTTGDLGYLHNGELFITGREKQEIIINGINYFAHEIETTIEELDGVAISYTAAFAVF 502
Query: 225 LQTPL--LLIVYFSAETLSSQE---LLDFLKCKLDEKYW--PDKVIRVDT--LPTNAHGK 275
QT LL++ FS E+ + +E L+ ++ L +K P VI ++ +P + GK
Sbjct: 503 DQTREVDLLVITFSPESNNVEEWVKLVREIRSHLTQKLGIAPSYVIPLEAALVPKTSIGK 562
Query: 276 TSKEILVNIYKKSNILQNVENIKSYLFKE---LKALVNKD-------LNYEDLQSKS--- 322
K L +++ ++ I YL KE ++L + + E LQ S
Sbjct: 563 VQKAKLKKDFEQGLFTTRIQEINEYLVKERNKTQSLPQSENERQIAAVWCEVLQLSSVGL 622
Query: 323 ---FFSLGGTSFLAVTICNKLSLTFPEVGKHILPHLLSHNKSIGDVLKTITQDTNCLENK 379
FF LGG S + + N L F + + + N ++ + +T+ +N +
Sbjct: 623 HDNFFELGGHSLYLIRVQNLLEKLFE---RQLPLAEMFKNSTVATLANFLTEPSNSTKAT 679
Query: 380 FKKSIKR--NRSTSSHGENSISYKKGAGGIRNSNTVE 414
+KS +R NRS SH + I+ AG +N ++
Sbjct: 680 EQKSRQRAENRSRRSHETHDIAIIGMAGRFPGANNLQ 716
>UniRef50_Q9GSP4 Cluster: Mutant e4 ebony; n=2; Drosophila|Rep:
Mutant e4 ebony - Drosophila melanogaster (Fruit fly)
Length = 735
Score = 58.4 bits (135), Expect = 7e-07
Identities = 44/189 (23%), Positives = 88/189 (46%), Gaps = 20/189 (10%)
Query: 120 VPLGNCLSETELFVQPHE----KNNTMGKIILASKTRKCILLNRKNGNK--------EEN 167
VP+G LS T +++ + KN +G+I + +N ++ + E+
Sbjct: 223 VPIGIPLSNTVVYLLDADYRPVKNGEIGEIFASGLNLAAGYVNGRDPERFLENPLAVEKK 282
Query: 168 SIKFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL-- 225
+ TGD G ++NG++ Y GR D +K GH+++L +E V + P V +
Sbjct: 283 YARLYRTGDYGSLKNGSIMYEGRTDSQVKIRGHRVDLSEVEKNVAELPLVDKAIVLCYHA 342
Query: 226 -QTPLLLIVYF----SAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEI 280
Q ++ + A ++ ++ LK KL + Y +V+ ++ +P +GK ++
Sbjct: 343 GQVDQAILAFVKLRDDAPMVTETQMEARLKDKLAD-YMTPQVVILEHVPLLVNGKVDRQA 401
Query: 281 LVNIYKKSN 289
L+ Y+ +N
Sbjct: 402 LLKTYETAN 410
>UniRef50_UPI000045BBC7 Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal peptide
synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 1420
Score = 58.0 bits (134), Expect = 9e-07
Identities = 71/334 (21%), Positives = 137/334 (41%), Gaps = 23/334 (6%)
Query: 33 VTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFT 92
VT TPS F Q N + L+++ GGE L + + + +++
Sbjct: 1021 VTVLNQTPSAFRQLMNAEEEAAGKTGTLALRLVIFGGETLELDSLQPWFERHGDGSQLVN 1080
Query: 93 LYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHEKN----NTMGKIILA 148
+YG+TE + + +++ + + + +G+ + + ++++ ++ G++ +
Sbjct: 1081 MYGITETTVHVTYRPINIADLNQRNGSL-IGHRIPDLQIYLLDSQRQPVPIGVAGELYIG 1139
Query: 149 SKTRKCILLNRK---------NGNKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRF 198
LNR N E +GD+ + NG + Y GR+D +K
Sbjct: 1140 GAGVTRGYLNRPELTAERFIVNPFSEVTDAYLYKSGDLARYLPNGELEYLGRIDHQVKIR 1199
Query: 199 GHKINLHSIESTVMQCPRVRSCSCVWLQTP------LLLIVYFSAETLSSQELLDFLKCK 252
G +I L IE+ + + VR ++ + +V + ++ +L FLK K
Sbjct: 1200 GFRIELGEIETALRKHQAVREVIVQAVEESHGEKRLVGYVVLDDKQAVTIGDLQRFLKEK 1259
Query: 253 LDEKYWPDKVIRVDTLPTNAHGKTSKEIL-VNIYKKSNILQNVENIKSYLFKELKALVNK 311
L E P I + LP +GK + L + N+ ++ + + + + K
Sbjct: 1260 LPEYMVPSAFIFLPALPLTPNGKLDRRSLPAPETIRPNLSDAYVMPQTEMEQTIATIWQK 1319
Query: 312 DLNYEDLQ-SKSFFSLGGTSFLAVTICNKLSLTF 344
LN E + +FF LGG S L V + +KL F
Sbjct: 1320 ALNIEKIGIHDNFFELGGHSLLMVKVHSKLREIF 1353
>UniRef50_Q8G982 Cluster: Peptide synthetase; n=102;
Cyanobacteria|Rep: Peptide synthetase - Oscillatoria
agardhii (Planktothrix agardhii)
Length = 2144
Score = 58.0 bits (134), Expect = 9e-07
Identities = 73/304 (24%), Positives = 136/304 (44%), Gaps = 38/304 (12%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
LK + GGE L+ + + +H N + LYG TE S A+ + T D +
Sbjct: 737 LKRVFCGGEALSSELMQQFFQHFN--CELHNLYGPTETSVDATCWQCPPR---TDDPAIA 791
Query: 122 LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE------NSIKF 171
+G ++ T++++ +G++ + LN+ E+ K
Sbjct: 792 IGRPIANTQIYILDRHLQPVPVGIVGELHIGGIPLARGYLNQLELTAEKFIPNPFGQGKL 851
Query: 172 IDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP-- 228
TGD+ + +G + Y GR+D+ +K G +I L I++ + P++ S V +QT
Sbjct: 852 YKTGDLVRYLADGNIEYLGRIDNQVKLRGLRIELGEIQTILDSHPQINQ-SVVIIQTDSE 910
Query: 229 --LLLIVYFSA--ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNI 284
L+ Y + + L+ +EL FL+ KL P + + P NA+GK + L
Sbjct: 911 DNQRLVAYVDSQNQALTPKELRQFLQPKLPAYMIPSAFVILPEFPLNANGKVDLKKLPQ- 969
Query: 285 YKKSNILQNV--------ENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTI 336
++ ++++V E I +++E+ +L +N +FF LGG S A+T+
Sbjct: 970 PNETALVESVYVAPRNPTETILVNIWQEVLSLAKIGIN------DNFFELGGHSLKAITL 1023
Query: 337 CNKL 340
+K+
Sbjct: 1024 VSKI 1027
Score = 48.8 bits (111), Expect = 5e-04
Identities = 87/369 (23%), Positives = 155/369 (42%), Gaps = 33/369 (8%)
Query: 3 EILLACTNGASLLIAPDLT----EVLFHEDNDNSVTFWQTTPS--KFFQHSNENIKNKIL 56
E L+ +G +L I + E L + + T PS + F + N+ N
Sbjct: 1754 ETLVTLCSGGTLYIPDSIDREDLERLLLRLGEWQINLLHTVPSVMRLFLNIGRNLPNANQ 1813
Query: 57 CARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDL-NKVTT 115
++ L+VL LGGEPL ++ + + N+T +YG +E + + N ++
Sbjct: 1814 LLKN-LQVLVLGGEPLFVKELCEWHEVFGNQTEFVNIYGASETTFIKHFHRIPKPNNISY 1872
Query: 116 GDKEVPLGNCLSETELFVQPHEKNNTMGKI---------ILASKTRKCILLNR---KNGN 163
VP G L + V + +G++ + + IL N N
Sbjct: 1873 A--RVPGGKTLPDAAFAVIDENRPCAIGEVGEIFVKSPYLTKGYYQDEILTNSVFVPNPL 1930
Query: 164 KEENSIKFIDTGDIGEIRNG-TVFYRGR-VDDTIKRFGHKINLHSIESTVMQCPRVRSCS 221
N + + TGD+G + T+ GR D+ IK G +I L IE V V+
Sbjct: 1931 NNGNDLVY-RTGDLGRLLPDLTLEVIGRRSDNQIKLNGVRIELGEIEDAVAAIDGVQKAL 1989
Query: 222 CVWLQTPLLLIV---YFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSK 278
+ + L+ V Y T++ +++ LK L P +I++++ P +GK +
Sbjct: 1990 VIADKKEELVTVIAYYQGNNTVNREQISQKLKQVLPTYMQPTFLIQLESFPLLPNGKIHR 2049
Query: 279 EILVNIYKKSNILQNVENIKSYLFKE-LKALVNKDLNYEDLQ--SKSFFSLGGTSFLAVT 335
L + NI Q++ + +E L ALV +L ++ ++SFF LGG S A+
Sbjct: 2050 LALPK--PEGNITQSISQPTGFNQQEALLALVWGELLEIEVSDNNQSFFELGGNSLKAMR 2107
Query: 336 ICNKLSLTF 344
+ +++ F
Sbjct: 2108 LVSQIRNQF 2116
>UniRef50_Q4C3C0 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation:Thioester reductase; n=1; Crocosphaera
watsonii WH 8501|Rep: Non-ribosomal peptide
synthase:Amino acid adenylation:Thioester reductase -
Crocosphaera watsonii
Length = 1993
Score = 58.0 bits (134), Expect = 9e-07
Identities = 51/174 (29%), Positives = 84/174 (48%), Gaps = 8/174 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTP---L 229
TGD+ + +G + + GR+D+ +K G++I L IE+T+ Q VR + +
Sbjct: 908 TGDLVRYLPDGNIEFIGRIDNQVKIRGYRIELGEIEATLRQHNGVRESVVLSHEEESGNK 967
Query: 230 LLIVYFSAE---TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYK 286
L+ Y E TL++ EL FL+ KL P I ++ LP GK ++ L
Sbjct: 968 YLVAYVVPEKQFTLTTAELQGFLQDKLPSYMVPPTFIYLNALPLLPSGKVNRRELPAPDS 1027
Query: 287 KSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNK 339
++N+ N ++ K+L + K L E + +FF LGG S L++ I K
Sbjct: 1028 RANLTGNYVAPRTANEKKLAEIWAKMLQLEQVGIYNNFFELGGDSILSMQIIAK 1081
>UniRef50_Q1ER08 Cluster: Cereulide synthetase 1; n=6; Bacillus|Rep:
Cereulide synthetase 1 - Bacillus cereus
Length = 3391
Score = 58.0 bits (134), Expect = 9e-07
Identities = 71/312 (22%), Positives = 136/312 (43%), Gaps = 31/312 (9%)
Query: 51 IKNKILCARSTLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDL 110
+ K + LK + + GE ++ + H N ++ LYG TE + +A+ +
Sbjct: 2041 LDEKDFAIMNRLKYIIVAGEAVSPELCNRLYAHCPN-VKLENLYGPTEGTIYAT--GFSI 2097
Query: 111 NKVTTGDKEVPLGNCLSETELFVQPHEKNNT-----------MGKIILASKTRKCILLNR 159
+K VP+G LS E ++ ++NN +G I +A K +L
Sbjct: 2098 HK-EMNVANVPIGKPLSHVETYIL--DQNNQIVPIGVPGELCLGGICVAKGYMKEPVLTE 2154
Query: 160 KNG--NKEENSIKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPR 216
+ N + S + TGD+ + +G + Y GR+D+ +K G +I L IE+ +
Sbjct: 2155 EKFVVNPMKQSERMYRTGDLVRWLADGNIEYLGRIDNQVKIRGFRIELGEIEAAIAALED 2214
Query: 217 VRSCSCVWL---QTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAH 273
V + + ++ Y +E + + + +K L + P + + LP N +
Sbjct: 2215 VVQTIVTTMTDHKGANKIVAYVVSEKYDEERIREHVKKTLPQYMVPSYFVSMKALPLNKN 2274
Query: 274 GKTSKEIL--VNIYKKS--NILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGG 328
GK ++ L V++Y+ S ++ N K + L + + L E++ +FF LGG
Sbjct: 2275 GKVDRKQLHSVDLYETSMDTVIVGPRNEKEAM---LSVIWQELLGLENISVHDNFFKLGG 2331
Query: 329 TSFLAVTICNKL 340
S LA+ + ++
Sbjct: 2332 DSILAIQMIGRV 2343
>UniRef50_Q08XI8 Cluster: Beta-lactamase, putative; n=3; Bacteria|Rep:
Beta-lactamase, putative - Stigmatella aurantiaca DW4/3-1
Length = 3136
Score = 58.0 bits (134), Expect = 9e-07
Identities = 71/302 (23%), Positives = 128/302 (42%), Gaps = 26/302 (8%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S++ L L GEPL+G +++ L + +F LYG TE + +++ + + E
Sbjct: 1454 SSIHTLNLAGEPLSG-SLVRALYSLPSIQHVFNLYGPTEDTTYSTFTLIPKD----ASSE 1508
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKE---------E 166
+G +S T +V + + G++ L+ +NR E E
Sbjct: 1509 PTIGRPISGTRAYVLDRQLHLVPRGVPGELYLSGSGLARGYINRPELTAERFLPNPFSTE 1568
Query: 167 NSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV-W 224
+ TGD+ +G + Y GR+D +K G +I L IES ++ P + + +
Sbjct: 1569 PGSRLYKTGDLARFAVDGNLEYLGRIDHQVKIRGFRIELGEIESILLTQPGLHQAAVLAH 1628
Query: 225 LQTP--LLLIVYFSA---ETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKE 279
+ P L+ Y A + + EL LK +L + P + +D LP +GK ++
Sbjct: 1629 EEAPGDKRLVAYVVAARNHSFTPAELRRLLKERLPDYMVPSAFVLLDALPLTPNGKLDRK 1688
Query: 280 ILVNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKS-FFSLGGTSFLAVTICN 338
L S + + K L + + LN + + + FF LGG S LA + +
Sbjct: 1689 ALPRPGAPSLEQKGFVPPHTQTEKALAEMWCELLNIDRVGIQDHFFELGGHSLLASQVIS 1748
Query: 339 KL 340
++
Sbjct: 1749 RI 1750
>UniRef50_A6DB12 Cluster: Acyl-CoA synthase; n=1; Caminibacter
mediatlanticus TB-2|Rep: Acyl-CoA synthase -
Caminibacter mediatlanticus TB-2
Length = 519
Score = 58.0 bits (134), Expect = 9e-07
Identities = 59/222 (26%), Positives = 96/222 (43%), Gaps = 12/222 (5%)
Query: 68 GGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP-LGNCL 126
G L G ++L+ K K ++ YG++E S +V L K + +P + +
Sbjct: 289 GAAALPG-EVLERFSKKFKKAKLLEGYGLSETSPVVAVNRPYLQKPGSVGPAIPGVEVKI 347
Query: 127 SETELFVQPHEKNNTMGKIILASKTRKCILLNRKNGNKEENSIKFIDTGDIGEI-RNGTV 185
EL P + G+II+ NR N+E + TGDIG++ +G +
Sbjct: 348 VNDELIEVPIGE---AGEIIVKGDIVMKGYYNRDEANEECLINGWFLTGDIGKVDEDGFI 404
Query: 186 FYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWL------QTPLLLIVYFSAET 239
+ R D I G I IE +++ P ++ C+ V L + P+ I
Sbjct: 405 YILDRKKDLIISKGVNIYPREIEEIILKFPGIKDCAVVGLKDENHGEIPVAFIEVEEDME 464
Query: 240 LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
++ ++L +LK KL P + V+ LP NA GK K IL
Sbjct: 465 VNEKDLRKYLKSKLANYKLPKYIYFVENLPKNATGKVLKRIL 506
>UniRef50_A3YFF7 Cluster: Amino acid adenylation; n=1; Marinomonas
sp. MED121|Rep: Amino acid adenylation - Marinomonas sp.
MED121
Length = 3118
Score = 58.0 bits (134), Expect = 9e-07
Identities = 73/315 (23%), Positives = 140/315 (44%), Gaps = 38/315 (12%)
Query: 1 MVEILLACTNGASLLI--APDLTEV-LFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILC 57
+ EI A NGA+L++ +L E +F E + + S F EN +
Sbjct: 206 LFEIWGALLNGATLVVFSQKELFEPSVFAEKVHKAKIDYAFLTSTLFNFMVENH----VA 261
Query: 58 ARSTLKVLALGGEPLNG--IKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTT 115
A + +K L +GGE L+ K E + + K++++ YG TE + ++ L+ +++
Sbjct: 262 AITQIKHLLVGGEALSAHASKRFFEAQGASIKSQLYNAYGPTECTTFSLCHALEATRLSE 321
Query: 116 GDKE--VPLGNCLSETE-LFVQPHEK---NNTMGKIIL------------ASKTRKCILL 157
++ VP+G + +T L ++ + K G++ L A +T K
Sbjct: 322 YQQKGRVPIGVAIGQTSILIIKENNKIALKGEKGELYLSGPSLAEGYLNDAVQTEKRFTF 381
Query: 158 NRKNGNKEENSIKFIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPR 216
G +N + TGD+ + N V Y GR+DD +K GH++ + I+ ++ P
Sbjct: 382 RADLGANSQNL--WYKTGDLVVLNDNNEVDYLGRLDDQVKIRGHRVEVGEIDHYLLTHPY 439
Query: 217 VRSCSCVWLQTPL--------LLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTL 268
++ + + L L++ + LS Q++ ++LK L P ++ D +
Sbjct: 440 IKEAATFGVSQSLGEKDLYSYLVLNQENNNALSKQDVKEYLKHSLPSYMLPHRIFITDKM 499
Query: 269 PTNAHGKTSKEILVN 283
P A+ K K+ L++
Sbjct: 500 PLTANQKLDKKRLLS 514
>UniRef50_A0ZF81 Cluster: Amino acid adenylation protein; n=3;
Bacteria|Rep: Amino acid adenylation protein - Nodularia
spumigena CCY 9414
Length = 2558
Score = 58.0 bits (134), Expect = 9e-07
Identities = 76/305 (24%), Positives = 131/305 (42%), Gaps = 36/305 (11%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTR-IFTLYGVTEMSCWASVAELDLNKVTTGDKEV 120
L+ L +GGE EL + TR F YG TE + AS+ + N K+
Sbjct: 755 LQALIIGGEACAA-----ELVEQWGTTRSFFNCYGPTESTVIASIFRCEPN-----GKKP 804
Query: 121 PLGNCLSETELFV-QPHEKN---NTMGKIILASKTRKCILLNRKNGNKEE--------NS 168
+G ++ +++ PH + G++ +A LNR E+
Sbjct: 805 SIGQPIANNSIYILDPHNQPLPPGIPGELCIAGVGLARGYLNRPETTSEKFMEIDLFGKV 864
Query: 169 IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT 227
+ TGD+ +G + Y GR+D+ +K G +I L IES ++Q V+ + +T
Sbjct: 865 ERIYKTGDLARWCADGNLEYLGRIDEQVKLRGFRIELGEIESLLLQHSLVKEAVVILYET 924
Query: 228 ---PLLLIVYFSAE--TLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL- 281
P L+ AE E+ ++LK +L P +++ ++ LP A+GK + L
Sbjct: 925 DSNPRLVAYVTQAEKSVTLGIEIKEYLKNRLPNYMIPSQIMVLEQLPLTANGKLDRRGLP 984
Query: 282 -VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNK 339
N S++ V + L + L L + + +S +FF LGG S LA + +
Sbjct: 985 APNTAAASDLEIPVTPTEEILASLWQGL----LKIQSVGRSDNFFELGGHSLLATQLIAR 1040
Query: 340 LSLTF 344
+ +F
Sbjct: 1041 IRDSF 1045
Score = 37.5 bits (83), Expect = 1.3
Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Query: 244 ELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQNVENIKSYLFK 303
E DFL L + P + ++ LP +GK ++ L + ++E + K
Sbjct: 2411 EWRDFLGKTLPDYMIPSHFVVLEKLPLTPNGKVDRKALPAT-DTAVAATDIELPVTGTEK 2469
Query: 304 ELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNKLSLTF 344
L L K L YE + + +FF+LGG S LA +C ++ TF
Sbjct: 2470 LLAQLWAKLLKYEAISRQDNFFNLGGHSLLATQLCYRIRDTF 2511
Score = 37.1 bits (82), Expect = 1.8
Identities = 38/170 (22%), Positives = 75/170 (44%), Gaps = 22/170 (12%)
Query: 62 LKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVP 121
L+ L++GGE + + + ++ YG TE + A++A N K+ P
Sbjct: 1809 LQCLSVGGEACTA----ELVSQWGTEQSLYNCYGPTETTVTAALALCQPN-----GKKPP 1859
Query: 122 LGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE--------NSI 169
+G LS +++ + G++ +A LNR E+
Sbjct: 1860 IGKPLSNLRIYILDTDYQPLPPGIPGELCIAGVGLARGYLNRPELTAEKFIEIELFGKVE 1919
Query: 170 KFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVR 218
+ TGD+ + +G + Y GR+D +K G +I L IE+++++ P+++
Sbjct: 1920 RIYKTGDLARWLPDGNLEYLGRIDHQVKLRGFRIELSEIEASLLKHPKIQ 1969
>UniRef50_A0UVJ0 Cluster: Amino acid adenylation domain; n=2;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 1499
Score = 58.0 bits (134), Expect = 9e-07
Identities = 66/298 (22%), Positives = 122/298 (40%), Gaps = 19/298 (6%)
Query: 60 STLKVLALGGEPLNGIKILKELKHKNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKE 119
S++K +GGE L K IF YG TE + + D+ K G
Sbjct: 708 SSVKRFIVGGEDLKVALAHSIYKSFGGDIEIFNEYGPTETVVGCMIHKYDV-KNDLG-VS 765
Query: 120 VPLGNCLSETELFVQPHEKN----NTMGKIILASKTRKCILLNRKNGNKEE-------NS 168
VP+G ++++ N T+G++ ++ LNR+ KE
Sbjct: 766 VPIGIPADNIQIYILDKNLNPVPVETIGELYVSGAGVTRGYLNREELTKERFVDNPFIKG 825
Query: 169 IKFIDTGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT 227
K TGD+ + + G + Y GR D +K G++I L IE+ + + +
Sbjct: 826 SKMYKTGDLAKHLHGGEIVYMGRSDYQVKLRGYRIELGEIENYLFSHNSITDAIVIDRND 885
Query: 228 PL---LLIVYFSAET-LSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVN 283
L Y + T L E+ FL KL + P + + +LP ++GK +++L
Sbjct: 886 EKGNKYLCAYIVSTTDLDISEIRMFLSSKLPDYMLPSHFVILQSLPLTSNGKVDRKLLPE 945
Query: 284 IYKKSNILQNVENIKSYLFKELKALVNKDLNYEDLQ-SKSFFSLGGTSFLAVTICNKL 340
+ ++ +++ ++ + L + + + +F+ LGG S A+ I ++L
Sbjct: 946 PKLEEESKAYYCEFENDTEEKIIKVICEVLGIDKISPTDNFYQLGGDSIKAIQIASRL 1003
>UniRef50_UPI0000DAE7B3 Cluster: hypothetical protein
Rgryl_01001237; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01001237 - Rickettsiella
grylli
Length = 596
Score = 57.6 bits (133), Expect = 1e-06
Identities = 85/358 (23%), Positives = 153/358 (42%), Gaps = 44/358 (12%)
Query: 3 EILLACTNGASLLIAPDLTEVLFHEDN------DNSVTFWQTTPSKFFQHSNENIKNKIL 56
+I+ A +GA L+I P TE++ + + N++T + TP + K K+
Sbjct: 201 DIIRALASGAQLVICP--TEIILNPERLYKTLKKNAITIAEFTPIVLRKLIYYLKKEKL- 257
Query: 57 CARSTLKVLALGGEPLNGIKILKELK-HKNNKTRIFTLYGVTEMSCWASVAELDLNKVTT 115
+++L G + + +K KE K + + R+ YG TE + ++ E D
Sbjct: 258 -DLHFMRLLICGSD-IWTLKEYKEAKTYLSADARLINSYGTTETTIDSTYFECDETMSPF 315
Query: 116 GDKE-VPLGNCLSETELFVQPHEKNNT----MGKIILASKTRKCILLNRKNGNKEE---- 166
+ VPLG T++ + + G+I + LN+ KE+
Sbjct: 316 NELSLVPLGKPFPNTKIKILNEQLKECPPEIQGEIYIGGSGVSQGYLNQPTLTKEKFISF 375
Query: 167 ------NSIKFIDTGDIG-EIRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRS 219
N I F +GD+G + +G + +RGR D IK G ++L +E+ + P++
Sbjct: 376 SSTNGKNEI-FYKSGDVGCYLMDGNIAFRGRADTQIKIMGISVDLLEVENILNSYPKIEK 434
Query: 220 CSCVWL----QTPLLLIVYFSAETL-SSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHG 274
+ T L+ Y + + + ++ + FLK +L P +T P + HG
Sbjct: 435 AIVLHHSSLDSTEQFLVAYIQCDKIFNIKDYITFLKKRLPFYAIPVVYFPRNTFPVSPHG 494
Query: 275 KTSKEILVN--IY------KKSNILQNVENIKSYLFKELKALVNKDLNYEDLQSKSFF 324
K + L + IY +K+N +N NIK +L ++N+ LN L +FF
Sbjct: 495 KVDRLTLNHNLIYGEQRSNEKNNFNENKINIK--FEGKLLFILNRLLNIPHLTENNFF 550
>UniRef50_UPI0000510064 Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1;
Brevibacterium linens BL2|Rep: COG1020: Non-ribosomal
peptide synthetase modules and related proteins -
Brevibacterium linens BL2
Length = 1316
Score = 57.6 bits (133), Expect = 1e-06
Identities = 50/177 (28%), Positives = 80/177 (45%), Gaps = 7/177 (3%)
Query: 174 TGDIGEIRN-GTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV--WLQTPLL 230
TGDI R+ G + Y GR+DD +K G +I L IES + + P V V T
Sbjct: 852 TGDIARWRSDGALDYLGRIDDQVKIRGLRIELGEIESVLAEHPDVHRAVVVPHGAGTAAS 911
Query: 231 LIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNI 290
L Y A + L D+L +L + P + V LP A+GK ++ L + +
Sbjct: 912 LRGYVQASANNINGLRDWLVDRLPDYMVPSTLTCVGELPMTANGKLDRQRLPAPEEPLST 971
Query: 291 LQNVENIKSYLFKELKALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTFPEV 347
+++ + + ++ D D +FF +GGTS AV++ +L PE+
Sbjct: 972 RAPSTKLEAAIVRAFDEVLGTDHLGVD---SNFFDVGGTSLTAVSLVRRLE-DLPEI 1024
>UniRef50_Q9I157 Cluster: PvdL; n=23; root|Rep: PvdL - Pseudomonas
aeruginosa
Length = 4342
Score = 57.6 bits (133), Expect = 1e-06
Identities = 54/202 (26%), Positives = 97/202 (48%), Gaps = 18/202 (8%)
Query: 174 TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL-LL 231
TGD+ + NG V Y GR+D +K G +I L IE+ +++ P+VR + L +P
Sbjct: 2570 TGDLVRLCDNGQVEYVGRIDHQVKIRGFRIELGEIEARLLEHPQVREALVLALDSPSGKQ 2629
Query: 232 IVYFSAETLSSQE----------LLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEIL 281
+ + A ++ Q+ L LK +L + P ++ + +LP A+GK + L
Sbjct: 2630 LAGYVASAVAEQDEDAQAALREALKTHLKQQLPDYMVPAHLLLLASLPLTANGKLDRRAL 2689
Query: 282 VNIYKKSNILQNVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
N Q E +S L ++L + + LN E + +FF LGG S L++ + ++
Sbjct: 2690 PAPDPALN-RQAYEAPRSVLEQQLAGVWREVLNVERVGLGDNFFELGGDSILSIQVVSRA 2748
Query: 341 SLTFPEVGKHILPHLLSHNKSI 362
++G H P L ++++
Sbjct: 2749 R----QLGIHFSPRDLFQHQTV 2766
Score = 39.5 bits (88), Expect = 0.33
Identities = 41/167 (24%), Positives = 76/167 (45%), Gaps = 12/167 (7%)
Query: 182 NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQ--TPLLLIVYFS--- 236
+G + Y GR+D +K G +I I++ ++ P V V + L+ Y++
Sbjct: 1515 DGVLEYLGRLDQQVKLRGFRIEPEEIQARLLAQPGVAQAVVVIREGVAGSQLVGYYTGAV 1574
Query: 237 ---AETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQN 293
AE +Q L L+ +L E P +++R+ +P GK L + ++
Sbjct: 1575 GAEAEAEQNQRLRAALQAELPEYMVPTQLMRLAQMPLGPSGKLDTRALPEPVWQQR--EH 1632
Query: 294 VENIKSYLFKELKALVNKDLNYEDLQSK-SFFSLGGTSFLAVTICNK 339
VE ++ L + + A+ ++ L + + FF LGG S LA I ++
Sbjct: 1633 VEP-RTELQRRIAAIWSEVLGLPRVGLRDDFFELGGHSLLATRIVSR 1678
Score = 36.3 bits (80), Expect = 3.1
Identities = 17/47 (36%), Positives = 27/47 (57%)
Query: 165 EENSIKFIDTGDIGEIRNGTVFYRGRVDDTIKRFGHKINLHSIESTV 211
E + ++ TGD+G +R+G +F GR+ D + GH + IE TV
Sbjct: 423 ERDGRTWLRTGDLGFLRDGELFVTGRLKDMLIVRGHNLYPQDIERTV 469
>UniRef50_Q81T97 Cluster: D-alanine-activating
enzyme/D-alanine-D-alanyl carrier protein ligase; n=12;
Firmicutes|Rep: D-alanine-activating
enzyme/D-alanine-D-alanyl carrier protein ligase -
Bacillus anthracis
Length = 503
Score = 57.6 bits (133), Expect = 1e-06
Identities = 67/280 (23%), Positives = 117/280 (41%), Gaps = 26/280 (9%)
Query: 24 LFHEDNDNSVTFWQTTPSKFFQHSNENIKNKILCARSTLKVLALGGEPLNGIKILKELKH 83
LF + + W +TPS E ++ + +K GE L ++ ++L
Sbjct: 226 LFASLEQSDIQVWTSTPSFAEMCLMEASFSESMLPN--MKTFLFCGEVLPN-EVARKLIE 282
Query: 84 KNNKTRIFTLYGVTEMSCWASVAELDLNKVTTGDKEVPLGNCLSETELFVQPHE----KN 139
+ K I YG TE + + + +V K +P+G C S+ L + + +
Sbjct: 283 RFPKATIMNTYGPTEATVAVTGIHVT-EEVLDQYKSLPVGYCKSDCRLLIMKEDGTIAPD 341
Query: 140 NTMGKIILASKTRKCILLNRKNGNKEENSIKFID------TGDIGEIRNGTVFYRGRVDD 193
G+I++ + L + E + ID TGD G + NG +FY GR+D
Sbjct: 342 GEKGEIVIVGPSVSVGYLG--SPELTEKAFTMIDGERAYKTGDAGYVENGLLFYNGRLDF 399
Query: 194 TIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQT----PLLLIVYFSAETLSSQE--LLD 247
IK G+++ L IE + C V V ++ LL V E +E L
Sbjct: 400 QIKLHGYRMELEEIEHHLRACSYVEGAVIVPIKKGEKYDYLLAVVVPGEHSFEKEFKLTS 459
Query: 248 FLKCKLDEK---YW-PDKVIRVDTLPTNAHGKTSKEILVN 283
+K +L+E+ Y P K + ++P +GK ++ L++
Sbjct: 460 AIKKELNERLPNYMIPRKFMYQSSIPMTPNGKVDRKKLLS 499
>UniRef50_Q5QVG8 Cluster: Medium-chain acyl-CoA synthetase; n=4;
Gammaproteobacteria|Rep: Medium-chain acyl-CoA
synthetase - Idiomarina loihiensis
Length = 542
Score = 57.6 bits (133), Expect = 1e-06
Identities = 48/133 (36%), Positives = 64/133 (48%), Gaps = 11/133 (8%)
Query: 171 FIDTGDIGEIR-NGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCV------ 223
++ TGDI I G + R D IK G I+ IE+ V Q V SCV
Sbjct: 412 WLATGDIAVIDPEGFMKVVDRKKDVIKSGGEWISSLDIENFVSQHQAVNE-SCVIGVKHP 470
Query: 224 -WLQTPLLLIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILV 282
W + PLLL+V E+LS +++ +FL K+ + PD V+ VD LP GK K L
Sbjct: 471 KWDERPLLLVVLNKGESLSKEDIKNFLDGKIARWWMPDDVVFVDELPHTGTGKLIKNTLR 530
Query: 283 NIYKKSNILQNVE 295
Y+ N LQ E
Sbjct: 531 EQYQ--NYLQENE 541
>UniRef50_A4XWA8 Cluster: Amino acid adenylation domain; n=1;
Pseudomonas mendocina ymp|Rep: Amino acid adenylation
domain - Pseudomonas mendocina ymp
Length = 5328
Score = 57.6 bits (133), Expect = 1e-06
Identities = 50/200 (25%), Positives = 92/200 (46%), Gaps = 11/200 (5%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLLLI 232
+GD+ G + Y GR+D +K G +I L IE+ +++ P +R V L L+
Sbjct: 880 SGDLARWTEEGVLEYLGRIDHQVKLRGLRIELGEIEAALLEHPALR--EAVVLVRDQQLV 937
Query: 233 VYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQ 292
Y EL LK +L E P V++++ LP + +GK ++ L + + +
Sbjct: 938 AYVVGGDYDEVELRARLKQRLPEFMLPSHVMQLERLPLSPNGKLERKALP---EPQRVQR 994
Query: 293 NVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKLSLTFPEVGKHI 351
+ + + L +L + + L E + + +FF LGG S L++ I + G +
Sbjct: 995 DYQAPRPGLESQLANIWQELLGVERVGRDDNFFELGGDSILSLQIIARAR----RQGIEL 1050
Query: 352 LPHLLSHNKSIGDVLKTITQ 371
P L +SI ++ + T+
Sbjct: 1051 TPRQLFERQSIAELAQVATR 1070
Score = 55.6 bits (128), Expect = 5e-06
Identities = 45/169 (26%), Positives = 81/169 (47%), Gaps = 7/169 (4%)
Query: 174 TGDIGE-IRNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPLLLI 232
+GD+ G + Y GR+D +K G +I L IE+ +++ P +R V L L+
Sbjct: 3394 SGDLARWTEEGVLEYLGRIDHQVKLRGLRIELGEIEAALLEHPALR--EAVVLVRDQQLV 3451
Query: 233 VYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNILQ 292
Y EL LK +L E P V++++ LP + +GK ++ L + I +
Sbjct: 3452 AYVVGGDYDEVELRARLKQRLPEFMLPSHVMQLERLPLSPNGKLERKALP---EPQRIQR 3508
Query: 293 NVENIKSYLFKELKALVNKDLNYEDL-QSKSFFSLGGTSFLAVTICNKL 340
+ + + L +L + + L E + + FF+LGG S LA + +++
Sbjct: 3509 DYQAPRPGLESQLANIWQELLAVERVGREDDFFALGGHSLLATQLVSQI 3557
Score = 53.2 bits (122), Expect = 2e-05
Identities = 47/172 (27%), Positives = 77/172 (44%), Gaps = 9/172 (5%)
Query: 174 TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--L 230
TGD + +G + Y GR+D IK G +I + +E+ + C V V +
Sbjct: 2350 TGDRVRLGADGQLEYLGRLDQQIKLRGFRIEIGEVEAALKACAGVGEALVVVKDSAAGKR 2409
Query: 231 LIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNI 290
L+ Y S + LS EL LK +L P ++ ++ LP +GK ++ L ++
Sbjct: 2410 LVGYVSGQGLSESELKMQLKQRLPAHMVPSHILALERLPQLPNGKLDRQSLPEPQVEAGE 2469
Query: 291 LQNVENIKSYLFKEL--KALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKL 340
Q + L EL + L ++ +D FF LGG S LA + ++L
Sbjct: 2470 YQAPRTEQERLLAELWSELLEQPRISRDD----HFFELGGHSLLATQLISRL 2517
Score = 53.2 bits (122), Expect = 2e-05
Identities = 50/201 (24%), Positives = 86/201 (42%), Gaps = 11/201 (5%)
Query: 174 TGDIGEI-RNGTVFYRGRVDDTIKRFGHKINLHSIESTVMQCPRVRSCSCVWLQTPL--L 230
TGD + +G + Y GR+D IK G +I + +E+ + C V V +
Sbjct: 4437 TGDRVRLGADGQLEYLGRLDQQIKLRGFRIEIGEVEAALKACAGVGESLVVVKDSAAGKR 4496
Query: 231 LIVYFSAETLSSQELLDFLKCKLDEKYWPDKVIRVDTLPTNAHGKTSKEILVNIYKKSNI 290
L+ Y S + LS EL LK +L P ++ ++ LP +GK ++ L +
Sbjct: 4497 LVGYVSGQALSESELKAQLKQRLPSHMVPSHILALERLPLLPNGKLDRQSLPEPQVEGGE 4556
Query: 291 LQNVENIKSYLFKEL-KALVNKDLNYEDLQSKSFFSLGGTSFLAVTICNKLSLTFPEVGK 349
Q + L EL L+ D Q FF+LGG S ++++ +L + G
Sbjct: 4557 YQAPRTEQEQLLAELWGELLGSGQISRDAQ---FFALGGDSIQSLSLVTRLR----KAGW 4609
Query: 350 HILPHLLSHNKSIGDVLKTIT 370
+ P + + + D+ +T
Sbjct: 4610 ALTPKAVFQHPRLADLAAVMT 4630
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.135 0.409
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 860,877,679
Number of Sequences: 1657284
Number of extensions: 37204338
Number of successful extensions: 96346
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 228
Number of HSP's successfully gapped in prelim test: 1137
Number of HSP's that attempted gapping in prelim test: 93230
Number of HSP's gapped (non-prelim): 3031
length of query: 758
length of database: 575,637,011
effective HSP length: 106
effective length of query: 652
effective length of database: 399,964,907
effective search space: 260777119364
effective search space used: 260777119364
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 76 (34.7 bits)
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