Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001038-TA|BGIBMGA001038-PA|IPR001680|WD-40 repeat,
IPR013894|Domain of unknown function DUF1767,
IPR000449|Ubiquitin-associated, IPR010304|Survival motor neuron,
IPR011046|WD40-like, IPR009060|UBA-like, IPR002999|Tudor
(961 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein. 340 1e-92
BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A pr... 340 1e-92
BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein. 340 1e-92
AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens ... 338 7e-92
BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein. 335 4e-91
EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein. 320 2e-86
BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B pr... 320 2e-86
AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens ... 320 2e-86
AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein. 186 4e-46
AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein. 186 4e-46
U72342-1|AAC51111.1| 410|Homo sapiens platelet activating facto... 149 4e-35
L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencepha... 149 4e-35
L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencepha... 149 4e-35
BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating fac... 149 4e-35
AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating fac... 149 4e-35
AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker lissencep... 149 4e-35
BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69 pro... 144 2e-33
AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens ... 144 2e-33
AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein. 144 2e-33
AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker lissencep... 143 2e-33
BC060876-1|AAH60876.1| 650|Homo sapiens tudor domain containing... 142 5e-33
AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens ... 141 1e-32
BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5 prot... 139 4e-32
BX537910-1|CAD97894.1| 651|Homo sapiens hypothetical protein pr... 139 4e-32
BC030514-1|AAH30514.1| 651|Homo sapiens tudor domain containing... 139 4e-32
BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5 prot... 139 4e-32
AL512666-2|CAH74000.1| 651|Homo sapiens tudor domain containing... 139 4e-32
AL354764-2|CAH72281.1| 651|Homo sapiens tudor domain containing... 139 4e-32
AK024660-1|BAB14950.1| 651|Homo sapiens protein ( Homo sapiens ... 139 4e-32
AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens ... 139 4e-32
AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein pr... 139 4e-32
CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein. 136 3e-31
BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B pro... 136 3e-31
AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens ... 134 1e-30
L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencepha... 133 3e-30
M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.... 125 9e-28
CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein. 125 9e-28
CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein. 125 9e-28
BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide bind... 125 9e-28
BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide bind... 125 9e-28
BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide bind... 125 9e-28
BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide bind... 125 9e-28
BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide bind... 125 9e-28
BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide bind... 125 9e-28
BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide bind... 125 9e-28
BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide bind... 125 9e-28
BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide bind... 125 9e-28
BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide bind... 125 9e-28
AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7 ... 125 9e-28
AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide bind... 124 2e-27
AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit pro... 122 6e-27
EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein. 122 8e-27
BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5... 122 8e-27
AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5... 122 8e-27
CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein. 121 1e-26
BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80 (WD40-conta... 121 1e-26
BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat ... 121 1e-26
AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kD... 120 3e-26
AL512666-1|CAH73999.1| 129|Homo sapiens tudor domain containing... 117 2e-25
AL354764-1|CAH72280.1| 129|Homo sapiens tudor domain containing... 117 2e-25
BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide bind... 115 7e-25
AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide bind... 115 7e-25
AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide bind... 115 7e-25
AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subuni... 115 7e-25
AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymeras... 113 4e-24
AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription ... 113 4e-24
AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor ... 113 4e-24
X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein. 112 7e-24
U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100 pr... 112 7e-24
U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor pro... 112 7e-24
BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II,... 112 7e-24
AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II,... 112 7e-24
AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiatio... 112 7e-24
BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein. 111 1e-23
AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD rep... 111 1e-23
AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein. 111 1e-23
BC113421-1|AAI13422.1| 514|Homo sapiens transducin (beta)-like ... 109 5e-23
BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide bind... 109 5e-23
AK022956-1|BAB14331.1| 514|Homo sapiens protein ( Homo sapiens ... 109 5e-23
AF314544-1|AAK00301.1| 514|Homo sapiens nuclear receptor co-rep... 109 5e-23
AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide bind... 109 5e-23
AF268193-1|AAG44736.1| 514|Homo sapiens IRA1 protein. 109 5e-23
Y12781-1|CAA73319.1| 577|Homo sapiens transducin (beta) like 1 ... 109 6e-23
X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRN... 109 6e-23
CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein. 109 6e-23
BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide bind... 109 6e-23
BC052304-1|AAH52304.1| 577|Homo sapiens transducin (beta)-like ... 109 6e-23
BC032708-1|AAH32708.1| 526|Homo sapiens TBL1X protein protein. 109 6e-23
BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide bind... 109 6e-23
BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide bind... 109 6e-23
BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide bind... 109 6e-23
AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide bind... 109 6e-23
AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide bind... 109 6e-23
AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease acti... 109 6e-23
AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide bind... 109 6e-23
AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease acti... 109 6e-23
AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease acti... 109 6e-23
AB209608-1|BAD92845.1| 540|Homo sapiens transducin beta-like 1X... 109 6e-23
AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein. 109 6e-23
EF079890-1|ABN48555.1| 444|Homo sapiens ATG16 autophagy related... 107 2e-22
EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related... 107 2e-22
BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein. 107 2e-22
BC071846-1|AAH71846.1| 475|Homo sapiens ATG16L1 protein protein. 107 2e-22
AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein. 107 2e-22
AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein. 107 2e-22
AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens ... 106 3e-22
AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens ... 106 3e-22
AL117629-1|CAB56021.1| 192|Homo sapiens hypothetical protein pr... 106 4e-22
AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor p... 106 4e-22
AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease acti... 105 6e-22
M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transduci... 105 8e-22
M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein. 105 8e-22
CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein. 105 8e-22
BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide bind... 105 8e-22
BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide bind... 105 8e-22
BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide bind... 105 8e-22
AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide bind... 105 8e-22
AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein. 105 8e-22
BC127949-1|AAI27950.1| 314|Homo sapiens similar to hypothetical... 104 1e-21
AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38 pro... 104 1e-21
BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein. 104 2e-21
M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human signal-tr... 103 2e-21
BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec... 103 3e-21
EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein. 103 4e-21
BC130473-1|AAI30474.1| 522|Homo sapiens transducin (beta)-like ... 103 4e-21
BC130471-1|AAI30472.1| 522|Homo sapiens transducin (beta)-like ... 103 4e-21
BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec... 103 4e-21
AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec... 103 4e-21
AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens ... 103 4e-21
AF332222-1|AAK13474.1| 522|Homo sapiens transducin beta-like 1 ... 103 4e-21
AF332221-1|AAK13473.1| 522|Homo sapiens transducin beta-like 1 ... 103 4e-21
AF332220-1|AAK13472.1| 522|Homo sapiens transducin beta-like 1 ... 103 4e-21
BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide bind... 101 2e-20
BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide bind... 101 2e-20
BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide bind... 101 2e-20
AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa prot... 101 2e-20
Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-bindin... 100 2e-20
U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain pr... 100 2e-20
M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein. 100 2e-20
AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide bind... 100 2e-20
AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide bind... 100 2e-20
AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-bind... 100 2e-20
CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein. 99 4e-20
BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processin... 99 4e-20
BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processin... 99 4e-20
AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6 snRNP-spec... 99 4e-20
AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processin... 99 4e-20
AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processin... 99 4e-20
AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear rib... 99 4e-20
AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant p... 99 4e-20
AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease acti... 100 5e-20
AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog ... 100 5e-20
BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1 (Dr... 99 9e-20
BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein. 99 9e-20
AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens ... 99 9e-20
AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease acti... 99 9e-20
U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p... 98 1e-19
BT020045-1|AAV38848.1| 350|Homo sapiens unr-interacting protein... 98 1e-19
BT020044-1|AAV38847.1| 350|Homo sapiens unr-interacting protein... 98 1e-19
BC062306-1|AAH62306.1| 350|Homo sapiens serine/threonine kinase... 98 1e-19
BC000162-1|AAH00162.1| 350|Homo sapiens serine/threonine kinase... 98 1e-19
AY049776-1|AAL15433.1| 350|Homo sapiens unr-interacting protein... 98 1e-19
AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease acti... 98 1e-19
AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease acti... 98 1e-19
AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease acti... 98 1e-19
AJ010025-1|CAB38041.1| 350|Homo sapiens unr-interacting protein... 98 1e-19
AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease acti... 98 1e-19
AB024327-1|BAA75544.1| 350|Homo sapiens WD-40 repeat protein pr... 98 1e-19
BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61 pro... 98 2e-19
AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens ... 98 2e-19
AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease acti... 98 2e-19
AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination p... 98 2e-19
AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta subunit-... 98 2e-19
AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease acti... 97 2e-19
AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease acti... 97 2e-19
AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating fac... 97 3e-19
BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat dom... 97 3e-19
BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat dom... 97 3e-19
BC035409-1|AAH35409.1| 808|Homo sapiens transducin (beta)-like ... 97 3e-19
BC014007-1|AAH14007.1| 808|Homo sapiens TBL3 protein protein. 97 3e-19
BC010231-1|AAH10231.1| 808|Homo sapiens transducin (beta)-like ... 97 3e-19
AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4 prot... 97 3e-19
AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7 prot... 97 3e-19
AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10 pro... 97 3e-19
AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isof... 97 3e-19
AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens ... 97 3e-19
AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form p... 97 3e-19
AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form ... 97 3e-19
AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30 pro... 97 3e-19
AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isof... 97 3e-19
AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3 ... 97 3e-19
CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein. 96 5e-19
BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein. 95 1e-18
BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1... 95 1e-18
BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein. 95 1e-18
AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing ... 95 1e-18
AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1... 95 1e-18
U02609-1|AAA18945.1| 519|Homo sapiens transducin-like protein p... 94 2e-18
AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta subunit-... 93 3e-18
BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 93 6e-18
BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 93 6e-18
BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 93 6e-18
AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein ... 93 6e-18
BC039254-1|AAH39254.1| 893|Homo sapiens WDR47 protein protein. 91 2e-17
AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein. 91 2e-17
AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein. 91 2e-17
BX679664-5|CAH71327.1| 919|Homo sapiens WD repeat domain 47 pro... 91 2e-17
BX679664-4|CAH71326.1| 920|Homo sapiens WD repeat domain 47 pro... 91 2e-17
BX679664-3|CAH71325.1| 891|Homo sapiens WD repeat domain 47 pro... 91 2e-17
BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein. 91 2e-17
AL449266-4|CAI14352.1| 891|Homo sapiens WD repeat domain 47 pro... 91 2e-17
AL449266-3|CAI14353.1| 919|Homo sapiens WD repeat domain 47 pro... 91 2e-17
AL449266-2|CAI14351.1| 920|Homo sapiens WD repeat domain 47 pro... 91 2e-17
AB020700-1|BAA74916.2| 974|Homo sapiens KIAA0893 protein protein. 91 2e-17
X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer compl... 90 3e-17
BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein comple... 90 3e-17
AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens ... 89 5e-17
U63810-1|AAC24948.1| 339|Homo sapiens WD40 protein Ciao 1 protein. 89 9e-17
EF011618-1|ABK41108.1| 339|Homo sapiens CDW8/WDR39 protein. 89 9e-17
CR456802-1|CAG33083.1| 339|Homo sapiens CIAO1 protein. 89 9e-17
BC068499-1|AAH68499.1| 351|Homo sapiens THO complex 3 protein. 89 9e-17
BC066325-1|AAH66325.1| 327|Homo sapiens THOC3 protein protein. 89 9e-17
BC032812-1|AAH32812.1| 339|Homo sapiens cytosolic iron-sulfur p... 89 9e-17
BC006849-1|AAH06849.1| 351|Homo sapiens THO complex 3 protein. 89 9e-17
BC001395-1|AAH01395.1| 339|Homo sapiens cytosolic iron-sulfur p... 89 9e-17
AK223257-1|BAD96977.1| 339|Homo sapiens WD40 protein Ciao1 vari... 89 9e-17
AC004020-1|AAC23493.1| 339|Homo sapiens Unknown gene product pr... 89 9e-17
BC029520-1|AAH29520.1| 384|Homo sapiens WDSUB1 protein protein. 88 1e-16
AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3 prot... 88 1e-16
AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3 ... 88 1e-16
M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transduci... 88 2e-16
BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat dom... 88 2e-16
BC007620-1|AAH07620.1| 570|Homo sapiens TBL3 protein protein. 88 2e-16
AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b pro... 88 2e-16
AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats pr... 88 2e-16
AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats pr... 88 2e-16
AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats pr... 88 2e-16
AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein. 88 2e-16
BC034964-1|AAH34964.1| 920|Homo sapiens WD repeat domain 47 pro... 87 2e-16
BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS box-... 87 2e-16
AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD pr... 87 2e-16
AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein. 87 2e-16
BC002489-1|AAH02489.1| 606|Homo sapiens WD repeat domain 1 prot... 87 3e-16
AF020260-1|AAD05045.1| 534|Homo sapiens WDR1 protein protein. 87 3e-16
AF020056-1|AAD05044.1| 606|Homo sapiens WDR1 protein protein. 87 3e-16
AB010427-1|BAA31855.2| 606|Homo sapiens NORI-1 protein. 87 3e-16
BC000201-1|AAH00201.1| 606|Homo sapiens WD repeat domain 1 prot... 87 4e-16
AK222897-1|BAD96617.1| 606|Homo sapiens WD repeat-containing pr... 87 4e-16
AK222764-1|BAD96484.1| 606|Homo sapiens WD repeat-containing pr... 87 4e-16
AB209746-1|BAD92983.1| 624|Homo sapiens WD repeat-containing pr... 87 4e-16
BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS box-... 86 5e-16
AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens ... 86 5e-16
AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein. 86 5e-16
AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD ... 86 5e-16
AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein. 86 5e-16
U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein. 86 7e-16
BC038447-1|AAH38447.1| 1233|Homo sapiens COPA protein protein. 86 7e-16
AL513282-3|CAI12455.1| 1233|Homo sapiens coatomer protein comple... 86 7e-16
AL513282-2|CAI12454.1| 1224|Homo sapiens coatomer protein comple... 86 7e-16
AL445230-2|CAI15005.1| 1224|Homo sapiens coatomer protein comple... 86 7e-16
AL445230-1|CAI15004.1| 1233|Homo sapiens coatomer protein comple... 86 7e-16
AK123876-1|BAC85713.1| 428|Homo sapiens protein ( Homo sapiens ... 85 1e-15
Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats c... 85 2e-15
BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat ... 85 2e-15
AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat... 85 2e-15
AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat... 85 2e-15
AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat ... 85 2e-15
AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat ... 85 2e-15
AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat ... 85 2e-15
AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat ... 85 2e-15
AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A pro... 85 2e-15
AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant E3RS-Ika... 85 2e-15
BC036713-1|AAH36713.1| 542|Homo sapiens ATG16L2 protein protein. 84 3e-15
AK093017-1|BAC04021.1| 619|Homo sapiens protein ( Homo sapiens ... 84 3e-15
AK090597-1|BAC03485.1| 513|Homo sapiens protein ( Homo sapiens ... 83 3e-15
AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1 i... 83 5e-15
AF106683-1|AAD43036.1| 421|Homo sapiens WSB-1 protein. 83 5e-15
X95263-1|CAA64560.1| 919|Homo sapiens PWP2 protein. 82 1e-14
U56089-1|AAC50905.1| 919|Homo sapiens periodic tryptophan prote... 82 1e-14
U56085-1|AAC50904.1| 919|Homo sapiens periodic tryptophan prote... 82 1e-14
U53346-1|AAB08084.1| 919|Homo sapiens PWP2H protein protein. 82 1e-14
BC014988-1|AAH14988.1| 919|Homo sapiens PWP2 periodic tryptopha... 82 1e-14
BC013309-1|AAH13309.1| 919|Homo sapiens PWP2 periodic tryptopha... 82 1e-14
AP001753-1|BAA95553.1| 919|Homo sapiens periodic tryptophan pro... 82 1e-14
AB001517-2|BAA21137.1| 919|Homo sapiens PWP2 protein protein. 82 1e-14
AK074434-1|BAB85082.1| 293|Homo sapiens protein ( Homo sapiens ... 81 1e-14
AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide bin... 81 2e-14
AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal tra... 81 2e-14
BC026353-1|AAH26353.1| 677|Homo sapiens WD repeat domain 48 pro... 81 2e-14
AF468833-1|AAL78650.1| 677|Homo sapiens WD repeat endosomal pro... 81 2e-14
AB040882-1|BAA95973.2| 680|Homo sapiens KIAA1449 protein protein. 81 2e-14
AF240696-1|AAF82746.1| 275|Homo sapiens WSB1 isoform 2 protein. 79 6e-14
BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein. 79 7e-14
AB209201-1|BAD92438.1| 466|Homo sapiens WD repeat-containing pr... 79 7e-14
AB209438-1|BAD92675.1| 316|Homo sapiens PWP2 periodic tryptopha... 79 1e-13
BC005870-1|AAH05870.1| 315|Homo sapiens mitogen-activated prote... 78 1e-13
U17989-1|AAB81551.1| 713|Homo sapiens GS2NA protein. 77 3e-13
BC132673-1|AAI32674.1| 713|Homo sapiens striatin, calmodulin bi... 77 3e-13
BC126221-1|AAI26222.1| 713|Homo sapiens striatin, calmodulin bi... 77 3e-13
AF243424-1|AAF81201.1| 678|Homo sapiens SG2NA beta isoform prot... 77 3e-13
AK074217-1|BAB85020.1| 506|Homo sapiens protein ( Homo sapiens ... 76 7e-13
AL607085-2|CAI15166.1| 494|Homo sapiens novel protein protein. 75 9e-13
AK223195-1|BAD96915.1| 315|Homo sapiens mitogen-activated prote... 75 9e-13
AK093494-1|BAC04184.1| 476|Homo sapiens protein ( Homo sapiens ... 75 9e-13
BC012352-1|AAH12352.1| 366|Homo sapiens WDR31 protein protein. 75 1e-12
AL449305-1|CAI10961.1| 367|Homo sapiens WD repeat domain 31 pro... 75 1e-12
AL137066-1|CAH70096.1| 367|Homo sapiens WD repeat domain 31 pro... 75 1e-12
AK093240-1|BAC04106.1| 367|Homo sapiens protein ( Homo sapiens ... 75 1e-12
BC023662-1|AAH23662.2| 475|Homo sapiens RRP9, small subunit (SS... 75 2e-12
BC010048-1|AAH10048.1| 475|Homo sapiens RRP9, small subunit (SS... 75 2e-12
BC009879-1|AAH09879.1| 475|Homo sapiens RRP9, small subunit (SS... 75 2e-12
BC001113-1|AAH01113.1| 475|Homo sapiens RRP9, small subunit (SS... 75 2e-12
AK074891-1|BAC11271.1| 242|Homo sapiens protein ( Homo sapiens ... 75 2e-12
AJ001340-1|CAA04687.1| 475|Homo sapiens U3 snoRNP associated 55... 75 2e-12
BC106879-1|AAI06880.1| 731|Homo sapiens STRN protein protein. 74 2e-12
BC106878-1|AAI06879.1| 755|Homo sapiens STRN protein protein. 74 2e-12
AC007382-1|AAF66162.1| 616|Homo sapiens unknown protein. 74 2e-12
AB023199-1|BAA76826.2| 502|Homo sapiens KIAA0982 protein protein. 74 3e-12
AJ223814-1|CAA11560.1| 780|Homo sapiens striatin protein. 73 6e-12
L02547-1|AAA35691.1| 431|Homo sapiens cleavage stimulation fact... 72 9e-12
BT007138-1|AAP35802.1| 431|Homo sapiens cleavage stimulation fa... 72 9e-12
BC032551-1|AAH32551.1| 795|Homo sapiens phospholipase A2-activa... 72 9e-12
BC007425-1|AAH07425.1| 431|Homo sapiens cleavage stimulation fa... 72 9e-12
BC001011-1|AAH01011.1| 431|Homo sapiens cleavage stimulation fa... 72 9e-12
AL356133-3|CAH72641.1| 738|Homo sapiens phospholipase A2-activa... 72 9e-12
AL121914-12|CAI19328.1| 431|Homo sapiens cleavage stimulation f... 72 9e-12
AK223544-1|BAD97264.1| 748|Homo sapiens Hypothetical protein DK... 72 9e-12
AK002143-1|BAA92105.1| 544|Homo sapiens protein ( Homo sapiens ... 72 9e-12
AJ238243-1|CAB42881.1| 738|Homo sapiens phospholipase A2 activa... 72 9e-12
AF083395-1|AAD03030.1| 738|Homo sapiens phospholipase A2-activa... 72 9e-12
M95627-1|AAA68889.1| 452|Homo sapiens angio-associated migrator... 71 2e-11
CR456755-1|CAG33036.1| 452|Homo sapiens AAMP protein. 71 2e-11
BC039866-1|AAH39866.2| 434|Homo sapiens angio-associated, migra... 71 2e-11
BC020244-1|AAH20244.1| 429|Homo sapiens Similar to angio-associ... 71 2e-11
X96586-1|CAA65405.1| 917|Homo sapiens FAN protein protein. 71 3e-11
BC047921-1|AAH47921.1| 563|Homo sapiens WDR86 protein protein. 71 3e-11
AY358182-1|AAQ88549.1| 470|Homo sapiens SSGL9393 protein. 71 3e-11
BC041124-1|AAH41124.1| 917|Homo sapiens neutral sphingomyelinas... 70 3e-11
BC111490-1|AAI11491.1| 768|Homo sapiens BRWD3 protein protein. 69 6e-11
BC063041-1|AAH63041.1| 1129|Homo sapiens WD repeat and HMG-box D... 69 6e-11
BC043349-1|AAH43349.1| 612|Homo sapiens WDHD1 protein protein. 69 6e-11
BC005040-1|AAH05040.1| 613|Homo sapiens Unknown (protein for IM... 69 6e-11
BC000622-1|AAH00622.1| 613|Homo sapiens WDHD1 protein protein. 69 6e-11
AY497047-1|AAS45472.1| 1631|Homo sapiens bromodomain and WD repe... 69 6e-11
AY497046-1|AAS45471.1| 1802|Homo sapiens bromodomain and WD repe... 69 6e-11
AL669934-1|CAI95405.1| 1802|Homo sapiens bromodomain and WD repe... 69 6e-11
AL590031-1|CAI39936.2| 1802|Homo sapiens bromodomain and WD repe... 69 6e-11
AL512504-2|CAI95143.1| 1802|Homo sapiens bromodomain and WD repe... 69 6e-11
AK001642-1|BAA91803.1| 795|Homo sapiens protein ( Homo sapiens ... 69 6e-11
AJ006266-1|CAA06932.1| 1129|Homo sapiens AND-1 protein protein. 69 6e-11
BC016946-1|AAH16946.1| 342|Homo sapiens WD repeat domain 77 pro... 69 8e-11
BC011778-1|AAH11778.1| 342|Homo sapiens WD repeat domain 77 pro... 69 8e-11
BC009411-1|AAH09411.1| 330|Homo sapiens WDR77 protein protein. 69 8e-11
BC006477-1|AAH06477.1| 342|Homo sapiens WD repeat domain 77 pro... 69 8e-11
BC001679-1|AAH01679.1| 342|Homo sapiens WD repeat domain 77 pro... 69 8e-11
AY225316-1|AAP79114.1| 342|Homo sapiens androgen receptor cofac... 69 8e-11
AL390195-6|CAC36041.1| 342|Homo sapiens MEP50 protein (MEP50) p... 69 8e-11
AF478464-1|AAL79917.1| 342|Homo sapiens MEP50 protein protein. 69 8e-11
AB073603-1|BAD38641.1| 342|Homo sapiens putative protein produc... 69 8e-11
AY358264-1|AAQ88631.1| 313|Homo sapiens WD40 protein protein. 69 1e-10
AL121914-11|CAC12718.2| 345|Homo sapiens cleavage stimulation f... 69 1e-10
AK223189-1|BAD96909.1| 342|Homo sapiens methylosome protein 50 ... 69 1e-10
AB209669-1|BAD92906.1| 1903|Homo sapiens Telomerase protein comp... 68 1e-10
U05340-1|AAA19017.1| 499|Homo sapiens p55CDC protein. 68 2e-10
DQ473545-1|ABE96834.1| 499|Homo sapiens CDC20 cell division cyc... 68 2e-10
BT007388-1|AAP36052.1| 499|Homo sapiens CDC20 cell division cyc... 68 2e-10
BC114493-1|AAI14494.1| 1514|Homo sapiens MAPKBP1 protein protein. 68 2e-10
BC113983-1|AAI13984.1| 1231|Homo sapiens MAPKBP1 protein protein. 68 2e-10
BC110321-1|AAI10322.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC031294-1|AAH31294.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC024257-1|AAH24257.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC015998-1|AAH15998.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC013303-1|AAH13303.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC012827-1|AAH12827.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC012803-1|AAH12803.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC010044-1|AAH10044.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC009426-1|AAH09426.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC009425-1|AAH09425.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC006272-1|AAH06272.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC001088-1|AAH01088.1| 499|Homo sapiens cell division cycle 20 ... 68 2e-10
BC000624-1|AAH00624.1| 499|Homo sapiens CDC20 protein protein. 68 2e-10
AL139289-3|CAB92757.1| 499|Homo sapiens CDC20 cell division cyc... 68 2e-10
AF099644-1|AAD16405.1| 499|Homo sapiens cell cycle protein CDC2... 68 2e-10
AB177850-1|BAD66828.1| 1217|Homo sapiens KIAA0596 splice variant... 68 2e-10
AB011168-1|BAA25522.2| 1531|Homo sapiens KIAA0596 protein protein. 68 2e-10
AL163279-2|CAB90452.1| 2295|Homo sapiens homolog to cAMP respons... 67 2e-10
AJ292466-1|CAC44372.1| 2269|Homo sapiens WDR9 protein, form B p... 67 2e-10
AJ292465-1|CAC44371.1| 2320|Homo sapiens WDR9 protein, form A pr... 67 2e-10
AJ238214-1|CAC37033.2| 2269|Homo sapiens hypothetical protein pr... 67 2e-10
AB080587-1|BAD74072.1| 2199|Homo sapiens WD repeat protein WDR9-... 67 2e-10
AK123625-1|BAC85666.1| 129|Homo sapiens protein ( Homo sapiens ... 67 3e-10
U86136-1|AAC51107.1| 2627|Homo sapiens telomerase-associated pro... 66 4e-10
BC126107-1|AAI26108.1| 2627|Homo sapiens telomerase-associated p... 66 4e-10
BC110334-1|AAI10335.1| 454|Homo sapiens F-box and WD repeat dom... 66 4e-10
BC094728-1|AAH94728.1| 731|Homo sapiens ring finger and WD repe... 66 4e-10
BC018738-1|AAH18738.1| 454|Homo sapiens F-box and WD repeat dom... 66 4e-10
AY509921-1|AAS82851.1| 707|Homo sapiens constitutive photomorph... 66 4e-10
AL590723-3|CAI14643.1| 731|Homo sapiens ring finger and WD repe... 66 4e-10
AL590723-2|CAI14642.1| 564|Homo sapiens ring finger and WD repe... 66 4e-10
AL590723-1|CAI14641.1| 491|Homo sapiens ring finger and WD repe... 66 4e-10
AL513329-4|CAH72425.1| 731|Homo sapiens ring finger and WD repe... 66 4e-10
AL513329-2|CAH72423.1| 564|Homo sapiens ring finger and WD repe... 66 4e-10
AL513329-1|CAH72422.1| 491|Homo sapiens ring finger and WD repe... 66 4e-10
AL359265-3|CAH71140.1| 731|Homo sapiens ring finger and WD repe... 66 4e-10
AL359265-2|CAH71139.1| 564|Homo sapiens ring finger and WD repe... 66 4e-10
AL359265-1|CAH71138.1| 491|Homo sapiens ring finger and WD repe... 66 4e-10
AL162736-3|CAH73625.1| 731|Homo sapiens ring finger and WD repe... 66 4e-10
AL162736-2|CAH73624.1| 564|Homo sapiens ring finger and WD repe... 66 4e-10
AL162736-1|CAH73623.1| 491|Homo sapiens ring finger and WD repe... 66 4e-10
AL161911-2|CAI95113.1| 454|Homo sapiens F-box and WD-40 domain ... 66 4e-10
AK025789-1|BAB15239.1| 506|Homo sapiens protein ( Homo sapiens ... 66 4e-10
AK022484-1|BAB14051.1| 454|Homo sapiens protein ( Homo sapiens ... 66 4e-10
AF527539-1|AAQ08989.1| 731|Homo sapiens putative ubiquitin liga... 66 4e-10
AF508940-1|AAM34692.1| 731|Homo sapiens constitutive photomorph... 66 4e-10
AF176698-1|AAF13226.1| 422|Homo sapiens F-box protein FBW2 prot... 66 4e-10
AF145024-1|AAP97276.1| 422|Homo sapiens MD6 protein protein. 66 4e-10
AF129531-1|AAF04465.1| 422|Homo sapiens F-box protein Fbw2 prot... 66 4e-10
AF103939-1|AAD19904.1| 649|Homo sapiens echinoderm microtubule-... 66 7e-10
AB209773-1|BAD93010.1| 574|Homo sapiens echinoderm microtubule ... 66 7e-10
AL161911-3|CAI95114.1| 208|Homo sapiens F-box and WD-40 domain ... 65 1e-09
DQ120664-1|ABB92447.1| 456|Homo sapiens rcCDC20 protein. 64 2e-09
AB007918-1|BAA32294.2| 1628|Homo sapiens KIAA0449 protein protein. 64 3e-09
BC108280-1|AAI08281.1| 896|Homo sapiens echinoderm microtubule ... 63 4e-09
AL671518-1|CAI13321.1| 539|Homo sapiens cell division cycle 40 ... 63 4e-09
AL445068-1|CAI22519.1| 539|Homo sapiens cell division cycle 40 ... 63 4e-09
AK128679-1|BAC87566.1| 780|Homo sapiens protein ( Homo sapiens ... 63 4e-09
AK093146-1|BAC04073.1| 889|Homo sapiens protein ( Homo sapiens ... 63 4e-09
AB208903-1|BAD92140.1| 501|Homo sapiens pre-mRNA splicing facto... 63 4e-09
BC024267-1|AAH24267.1| 594|Homo sapiens TRAF7 protein protein. 63 5e-09
AY569455-1|AAS68363.1| 670|Homo sapiens TRAF7 protein. 63 5e-09
M99439-1|AAA61195.1| 448|Homo sapiens transducin-like enhancer ... 62 7e-09
BC107125-1|AAI07126.1| 248|Homo sapiens WDR86 protein protein. 62 7e-09
BC059405-1|AAH59405.2| 805|Homo sapiens TLE4 protein protein. 62 7e-09
BC045650-1|AAH45650.1| 704|Homo sapiens TLE4 protein protein. 62 7e-09
AL445252-3|CAI13644.1| 764|Homo sapiens transducin-like enhance... 62 7e-09
AL358975-3|CAI13734.1| 764|Homo sapiens transducin-like enhance... 62 7e-09
AL353813-5|CAI41315.1| 764|Homo sapiens transducin-like enhance... 62 7e-09
AB033087-1|BAA86575.1| 787|Homo sapiens KIAA1261 protein protein. 62 7e-09
AM177179-1|CAJ45483.1| 1621|Homo sapiens kinesin-like protein KI... 62 9e-09
AL833301-1|CAD91142.1| 1340|Homo sapiens hypothetical protein pr... 62 9e-09
AL832455-1|CAD89926.1| 1308|Homo sapiens hypothetical protein pr... 62 9e-09
AL832367-1|CAD91157.1| 820|Homo sapiens hypothetical protein pr... 62 9e-09
AL832352-1|CAD91149.1| 1337|Homo sapiens hypothetical protein pr... 62 9e-09
AL832014-1|CAD91147.1| 1264|Homo sapiens hypothetical protein pr... 62 9e-09
AF492460-1|AAN64030.1| 1322|Homo sapiens WD repeat 17 protein. 62 9e-09
AF209502-2|AAL40184.1| 1883|Homo sapiens ZFP106 protein. 62 9e-09
AF205632-1|AAG35666.1| 1883|Homo sapiens zinc finger protein 106... 62 9e-09
U88871-1|AAC51238.1| 323|Homo sapiens HsPex7p protein. 62 1e-08
U76560-1|AAB50556.1| 323|Homo sapiens peroxisome targeting sign... 62 1e-08
CR542076-1|CAG46873.1| 323|Homo sapiens PEX7 protein. 62 1e-08
CR542054-1|CAG46851.1| 323|Homo sapiens PEX7 protein. 62 1e-08
BC033043-1|AAH33043.1| 815|Homo sapiens echinoderm microtubule ... 62 1e-08
BC030541-1|AAH30541.1| 466|Homo sapiens WD repeat domain 1 prot... 62 1e-08
BC006268-1|AAH06268.1| 323|Homo sapiens peroxisomal biogenesis ... 62 1e-08
AM177180-1|CAJ45484.1| 1670|Homo sapiens kinesin-like protein KI... 62 1e-08
AL365223-4|CAI15714.1| 323|Homo sapiens peroxisomal biogenesis ... 62 1e-08
AL121933-2|CAI15471.1| 323|Homo sapiens peroxisomal biogenesis ... 62 1e-08
AF180814-1|AAF37350.1| 323|Homo sapiens peroxisomal PTS2 recept... 62 1e-08
AF145020-1|AAD42075.1| 649|Homo sapiens phospholipase A2 activa... 62 1e-08
M99435-1|AAA61192.1| 770|Homo sapiens transducin-like enhancer ... 61 2e-08
EF011617-1|ABK41107.1| 423|Homo sapiens CDW7/WDR12 protein. 61 2e-08
BC015747-1|AAH15747.1| 770|Homo sapiens transducin-like enhance... 61 2e-08
BC010100-1|AAH10100.1| 770|Homo sapiens transducin-like enhance... 61 2e-08
BC008082-1|AAH08082.1| 423|Homo sapiens WD repeat domain 12 pro... 61 2e-08
AL390195-5|CAI15627.1| 290|Homo sapiens MEP50 protein (MEP50) p... 61 2e-08
AL365190-2|CAI14977.1| 770|Homo sapiens transducin-like enhance... 61 2e-08
AL353682-1|CAI12595.1| 770|Homo sapiens transducin-like enhance... 61 2e-08
AK001743-1|BAA91875.1| 423|Homo sapiens protein ( Homo sapiens ... 61 2e-08
AF242546-1|AAF60355.1| 423|Homo sapiens YTM1 protein. 61 2e-08
AF070597-1|AAC28652.1| 127|Homo sapiens beta-subunit signal tra... 61 2e-08
AC010900-2|AAY24287.1| 423|Homo sapiens unknown protein. 61 2e-08
BX537855-1|CAD97863.1| 974|Homo sapiens hypothetical protein pr... 61 2e-08
BC047572-1|AAH47572.1| 433|Homo sapiens KIF21A protein protein. 61 2e-08
BC028628-1|AAH28628.1| 375|Homo sapiens WDR71 protein protein. 61 2e-08
BC021541-1|AAH21541.1| 392|Homo sapiens WD repeat domain 71 pro... 61 2e-08
BC006142-1|AAH06142.2| 392|Homo sapiens WD repeat domain 71 pro... 61 2e-08
AY368076-1|AAR04774.1| 1674|Homo sapiens kinesin family member 2... 61 2e-08
AK222721-1|BAD96441.1| 579|Homo sapiens pre-mRNA splicing facto... 61 2e-08
AK022782-1|BAB14243.1| 423|Homo sapiens protein ( Homo sapiens ... 61 2e-08
AK022781-1|BAB14242.1| 423|Homo sapiens protein ( Homo sapiens ... 61 2e-08
AK021910-1|BAB13933.1| 392|Homo sapiens protein ( Homo sapiens ... 61 2e-08
AF450487-1|AAP97680.1| 1662|Homo sapiens kinesin-like protein KI... 61 2e-08
AF087895-1|AAP97194.1| 375|Homo sapiens G-16 protein. 61 2e-08
AB051495-1|BAB21799.2| 1657|Homo sapiens KIAA1708 protein. 61 2e-08
BC133025-1|AAI33026.1| 951|Homo sapiens WD repeat domain 36 pro... 60 3e-08
BC126114-1|AAI26115.1| 579|Homo sapiens cell division cycle 40 ... 60 3e-08
BC117145-1|AAI17146.1| 579|Homo sapiens cell division cycle 40 ... 60 3e-08
AL671518-2|CAI13322.1| 579|Homo sapiens cell division cycle 40 ... 60 3e-08
AK095312-1|BAC04527.1| 895|Homo sapiens protein ( Homo sapiens ... 60 3e-08
AF385437-1|AAM43838.1| 951|Homo sapiens T-cell activation WD re... 60 3e-08
AF061241-1|AAC25166.1| 542|Homo sapiens splicing factor hPRP17 ... 60 3e-08
AF038392-1|AAC39730.1| 579|Homo sapiens pre-mRNA splicing facto... 60 3e-08
BC025392-1|AAH25392.1| 620|Homo sapiens WD repeat domain 16 pro... 60 4e-08
BC008809-1|AAH08809.2| 302|Homo sapiens AAMP protein protein. 60 4e-08
AK094847-1|BAC04435.1| 630|Homo sapiens protein ( Homo sapiens ... 60 4e-08
AK074435-1|BAB85083.1| 412|Homo sapiens protein ( Homo sapiens ... 60 4e-08
AB065281-1|BAB83743.1| 620|Homo sapiens WDR16 protein. 60 4e-08
X89887-1|CAA61979.1| 1017|Homo sapiens HIRA protein. 59 6e-08
X81844-1|CAA57436.1| 1017|Homo sapiens HIRA protein. 59 6e-08
X77633-1|CAA54721.1| 973|Homo sapiens HIRAHs protein. 59 6e-08
>BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein.
Length = 441
Score = 340 bits (836), Expect = 1e-92
Identities = 146/295 (49%), Positives = 209/295 (70%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
+P L++ KGH++A+T + ++ N +Q+A+ S+D+ +++W ++ R+YRF GH +AV V
Sbjct: 42 DPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCV 101
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVV 129
FS SG +AS SRDKTVRIWVP V G + +F+AH+ TVRSV F SDG +TASDDK V
Sbjct: 102 NFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTV 161
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
K+W+TH+ KF+ S H NWVRCA+ S DG +I S SDDK+ KLW+ S EC+H+Y +
Sbjct: 162 KVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHG 221
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
G ++ +HPSG +A A VK++D+RTH L+Q+Y +H+ AV ++ HPSG+Y++TA
Sbjct: 222 GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITA 281
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNF 304
S D +KILDL+EG ++TL GH GP V FS TG+ F+S G D+ V +WK+NF
Sbjct: 282 SSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNF 336
>BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A
protein.
Length = 407
Score = 340 bits (836), Expect = 1e-92
Identities = 146/295 (49%), Positives = 209/295 (70%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
+P L++ KGH++A+T + ++ N +Q+A+ S+D+ +++W ++ R+YRF GH +AV V
Sbjct: 8 DPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCV 67
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVV 129
FS SG +AS SRDKTVRIWVP V G + +F+AH+ TVRSV F SDG +TASDDK V
Sbjct: 68 NFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTV 127
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
K+W+TH+ KF+ S H NWVRCA+ S DG +I S SDDK+ KLW+ S EC+H+Y +
Sbjct: 128 KVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHG 187
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
G ++ +HPSG +A A VK++D+RTH L+Q+Y +H+ AV ++ HPSG+Y++TA
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITA 247
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNF 304
S D +KILDL+EG ++TL GH GP V FS TG+ F+S G D+ V +WK+NF
Sbjct: 248 SSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNF 302
>BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein.
Length = 359
Score = 340 bits (836), Expect = 1e-92
Identities = 146/295 (49%), Positives = 209/295 (70%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
+P L++ KGH++A+T + ++ N +Q+A+ S+D+ +++W ++ R+YRF GH +AV V
Sbjct: 8 DPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCV 67
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVV 129
FS SG +AS SRDKTVRIWVP V G + +F+AH+ TVRSV F SDG +TASDDK V
Sbjct: 68 NFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTV 127
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
K+W+TH+ KF+ S H NWVRCA+ S DG +I S SDDK+ KLW+ S EC+H+Y +
Sbjct: 128 KVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHG 187
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
G ++ +HPSG +A A VK++D+RTH L+Q+Y +H+ AV ++ HPSG+Y++TA
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITA 247
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNF 304
S D +KILDL+EG ++TL GH GP V FS TG+ F+S G D+ V +WK+NF
Sbjct: 248 SSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNF 302
>AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens
cDNA FLJ90808 fis, clone Y79AA1000777, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 407
Score = 338 bits (830), Expect = 7e-92
Identities = 145/295 (49%), Positives = 209/295 (70%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
+P L++ KGH++A+T + ++ N +Q+A+ S+D+ +++W ++ R+YRF GH +AV V
Sbjct: 8 DPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCV 67
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVV 129
FS SG +AS SRDKTVRIWVP V G + +F+AH+ TVRSV F SDG +TASDDK V
Sbjct: 68 NFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTV 127
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
K+W+TH+ KF+ S H NWVRCA+ S DG +I S SDDK+ KLW+ S EC+H+Y +
Sbjct: 128 KVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHG 187
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
G ++ +HPSG +A A VK++D+RT+ L+Q+Y +H+ AV ++ HPSG+Y++TA
Sbjct: 188 GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYRLLQHYQLHSAAVNGLSFHPSGNYLITA 247
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNF 304
S D +KILDL+EG ++TL GH GP V FS TG+ F+S G D+ V +WK+NF
Sbjct: 248 SSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNF 302
>BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein.
Length = 396
Score = 335 bits (824), Expect = 4e-91
Identities = 144/291 (49%), Positives = 206/291 (70%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ KGH++A+T + ++ N +Q+A+ S+D+ +++W ++ R+YRF GH +AV V FS
Sbjct: 1 ERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSP 60
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
SG +AS SRDKTVRIWVP V G + +F+AH+ TVRSV F SDG +TASDDK VK+W+
Sbjct: 61 SGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWA 120
Query: 134 THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGL 193
TH+ KF+ S H NWVRCA+ S DG +I S SDDK+ KLW+ S EC+H+Y + G
Sbjct: 121 THRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVT 180
Query: 194 HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDG 253
++ +HPSG +A A VK++D+RTH L+Q+Y +H+ AV ++ HPSG+Y++TAS D
Sbjct: 181 YVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDS 240
Query: 254 KMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNF 304
+KILDL+EG ++TL GH GP V FS TG+ F+S G D+ V +WK+NF
Sbjct: 241 TLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNF 291
>EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein.
Length = 478
Score = 320 bits (785), Expect = 2e-86
Identities = 140/300 (46%), Positives = 206/300 (68%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVM 67
T +P L++ KGHK AIT+L +PN +Q+AT+S D ++LW+ + R+YR+ GH + V
Sbjct: 5 TEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVT 64
Query: 68 DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK 127
V FS G +ASASRD+TVR+W+P G FKAH+ VRSV FS+DG + TAS+DK
Sbjct: 65 SVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDK 124
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
+K+WS ++ +F+ S HT+WVRCA+ S DG +I SCS+DK+ K+W+ + +C++ + D
Sbjct: 125 SIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSD 184
Query: 188 LKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL 247
G + ++PSG +A A S VK++D+R + L+Q+Y +H+ V ++ HPSG+Y++
Sbjct: 185 SVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLI 244
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
TAS DG +KILDLLEG I+TL GH GPV V+FS G+ F+S G D V +W+TNF +L
Sbjct: 245 TASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDEL 304
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/252 (24%), Positives = 115/252 (45%), Gaps = 3/252 (1%)
Query: 101 FKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS 160
FK H + S+ S +G ++ TAS D + LW+ H +VGH + V + S G+
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 161 IIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRT 220
++AS S D++ +LW D +K + + G ++A A+ ++K++ +
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Query: 221 HNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ H V P G I++ S+D +KI D + S G N V+
Sbjct: 134 QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVD 193
Query: 281 FSPTGDTFSSAGDDKLVFIWKTNFTDLSSESK-ENEGQNMITGQRHLTEEGIDTITENGQ 339
F+P+G +SAG D+ V +W L + + G N I+ H + + T + +G
Sbjct: 194 FNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCIS--FHPSGNYLITASSDGT 251
Query: 340 IQDVNILSKKAL 351
++ +++L + +
Sbjct: 252 LKILDLLEGRLI 263
>BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B
protein.
Length = 478
Score = 320 bits (785), Expect = 2e-86
Identities = 140/300 (46%), Positives = 206/300 (68%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVM 67
T +P L++ KGHK AIT+L +PN +Q+AT+S D ++LW+ + R+YR+ GH + V
Sbjct: 5 TEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVT 64
Query: 68 DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK 127
V FS G +ASASRD+TVR+W+P G FKAH+ VRSV FS+DG + TAS+DK
Sbjct: 65 SVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDK 124
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
+K+WS ++ +F+ S HT+WVRCA+ S DG +I SCS+DK+ K+W+ + +C++ + D
Sbjct: 125 SIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSD 184
Query: 188 LKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL 247
G + ++PSG +A A S VK++D+R + L+Q+Y +H+ V ++ HPSG+Y++
Sbjct: 185 SVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLI 244
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
TAS DG +KILDLLEG I+TL GH GPV V+FS G+ F+S G D V +W+TNF +L
Sbjct: 245 TASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDEL 304
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/252 (24%), Positives = 115/252 (45%), Gaps = 3/252 (1%)
Query: 101 FKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS 160
FK H + S+ S +G ++ TAS D + LW+ H +VGH + V + S G+
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 161 IIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRT 220
++AS S D++ +LW D +K + + G ++A A+ ++K++ +
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Query: 221 HNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ H V P G I++ S+D +KI D + S G N V+
Sbjct: 134 QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVD 193
Query: 281 FSPTGDTFSSAGDDKLVFIWKTNFTDLSSESK-ENEGQNMITGQRHLTEEGIDTITENGQ 339
F+P+G +SAG D+ V +W L + + G N I+ H + + T + +G
Sbjct: 194 FNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCIS--FHPSGNYLITASSDGT 251
Query: 340 IQDVNILSKKAL 351
++ +++L + +
Sbjct: 252 LKILDLLEGRLI 263
>AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens
cDNA FLJ90291 fis, clone NT2RP1001031, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 478
Score = 320 bits (785), Expect = 2e-86
Identities = 140/300 (46%), Positives = 206/300 (68%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVM 67
T +P L++ KGHK AIT+L +PN +Q+AT+S D ++LW+ + R+YR+ GH + V
Sbjct: 5 TEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVT 64
Query: 68 DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK 127
V FS G +ASASRD+TVR+W+P G FKAH+ VRSV FS+DG + TAS+DK
Sbjct: 65 SVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDK 124
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
+K+WS ++ +F+ S HT+WVRCA+ S DG +I SCS+DK+ K+W+ + +C++ + D
Sbjct: 125 SIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSD 184
Query: 188 LKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL 247
G + ++PSG +A A S VK++D+R + L+Q+Y +H+ V ++ HPSG+Y++
Sbjct: 185 SVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLI 244
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
TAS DG +KILDLLEG I+TL GH GPV V+FS G+ F+S G D V +W+TNF +L
Sbjct: 245 TASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDEL 304
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/252 (24%), Positives = 115/252 (45%), Gaps = 3/252 (1%)
Query: 101 FKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS 160
FK H + S+ S +G ++ TAS D + LW+ H +VGH + V + S G+
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 161 IIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRT 220
++AS S D++ +LW D +K + + G ++A A+ ++K++ +
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Query: 221 HNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ H V P G I++ S+D +KI D + S G N V+
Sbjct: 134 QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVD 193
Query: 281 FSPTGDTFSSAGDDKLVFIWKTNFTDLSSESK-ENEGQNMITGQRHLTEEGIDTITENGQ 339
F+P+G +SAG D+ V +W L + + G N I+ H + + T + +G
Sbjct: 194 FNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCIS--FHPSGNYLITASSDGT 251
Query: 340 IQDVNILSKKAL 351
++ +++L + +
Sbjct: 252 LKILDLLEGRLI 263
>AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein.
Length = 348
Score = 186 bits (452), Expect = 4e-46
Identities = 78/173 (45%), Positives = 119/173 (68%)
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
++ +F+ S HT+WVRCA+ S DG +I SCS+DK+ K+W+ + +C++ + D G
Sbjct: 2 YRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANF 61
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGK 254
+ ++PSG +A A S VK++D+R + L+Q+Y +H+ V ++ HPSG+Y++TAS DG
Sbjct: 62 VDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGT 121
Query: 255 MKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
+KILDLLEG I+TL GH GPV V+FS G+ F+S G D V +W+TNF +L
Sbjct: 122 LKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDEL 174
Score = 83.4 bits (197), Expect = 3e-15
Identities = 40/149 (26%), Positives = 73/149 (48%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
H+ VR +FS DG I++ S+DK +K+W T + +++F + + G+ IA
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 72
Query: 164 SCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNL 223
S D++ K+W++ + + Y+ G +++HPSG Y+ A+S G +K+ D+ L
Sbjct: 73 SAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRL 132
Query: 224 VQYYSIHNEAVTQVAIHPSGSYILTASKD 252
+ H V V+ G + D
Sbjct: 133 IYTLQGHTGPVFTVSFSKGGELFASGGAD 161
Score = 77.0 bits (181), Expect = 3e-13
Identities = 46/164 (28%), Positives = 72/164 (43%), Gaps = 2/164 (1%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMA 79
H + + ++P+ + I + S D ++ +WD F V F+ SG +A
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 72
Query: 80 SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKF 139
SA D+TV++W V ++ HS V + F G+ +ITAS D +K+ + +
Sbjct: 73 SAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRL 132
Query: 140 ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW--NLDSGEC 181
I + GHT V S G + AS D LW N D C
Sbjct: 133 IYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDELHC 176
Score = 70.1 bits (164), Expect = 3e-11
Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
Query: 57 YRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSD 116
Y H V FS G+ + S S DKT++IW T F V F+
Sbjct: 8 YSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPS 67
Query: 117 GSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNL 176
G+ I +A D+ VK+W +K + + H+ V C G+ + + S D + K+ +L
Sbjct: 68 GTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDL 127
Query: 177 DSGECIHTYKDLKGH 191
G I+T L+GH
Sbjct: 128 LEGRLIYT---LQGH 139
Score = 46.0 bits (104), Expect = 6e-04
Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 3/123 (2%)
Query: 230 HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFS 289
H V P G I++ S+D +KI D + S G N V+F+P+G +
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 72
Query: 290 SAGDDKLVFIWKTNFTDLSSESK-ENEGQNMITGQRHLTEEGIDTITENGQIQDVNILSK 348
SAG D+ V +W L + + G N I+ H + + T + +G ++ +++L
Sbjct: 73 SAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCIS--FHPSGNYLITASSDGTLKILDLLEG 130
Query: 349 KAL 351
+ +
Sbjct: 131 RLI 133
>AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein.
Length = 348
Score = 186 bits (452), Expect = 4e-46
Identities = 78/173 (45%), Positives = 119/173 (68%)
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
++ +F+ S HT+WVRCA+ S DG +I SCS+DK+ K+W+ + +C++ + D G
Sbjct: 2 YRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANF 61
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGK 254
+ ++PSG +A A S VK++D+R + L+Q+Y +H+ V ++ HPSG+Y++TAS DG
Sbjct: 62 VDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGT 121
Query: 255 MKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
+KILDLLEG I+TL GH GPV V+FS G+ F+S G D V +W+TNF +L
Sbjct: 122 LKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDEL 174
Score = 83.4 bits (197), Expect = 3e-15
Identities = 40/149 (26%), Positives = 73/149 (48%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
H+ VR +FS DG I++ S+DK +K+W T + +++F + + G+ IA
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 72
Query: 164 SCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNL 223
S D++ K+W++ + + Y+ G +++HPSG Y+ A+S G +K+ D+ L
Sbjct: 73 SAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRL 132
Query: 224 VQYYSIHNEAVTQVAIHPSGSYILTASKD 252
+ H V V+ G + D
Sbjct: 133 IYTLQGHTGPVFTVSFSKGGELFASGGAD 161
Score = 77.0 bits (181), Expect = 3e-13
Identities = 46/164 (28%), Positives = 72/164 (43%), Gaps = 2/164 (1%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMA 79
H + + ++P+ + I + S D ++ +WD F V F+ SG +A
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 72
Query: 80 SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKF 139
SA D+TV++W V ++ HS V + F G+ +ITAS D +K+ + +
Sbjct: 73 SAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRL 132
Query: 140 ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW--NLDSGEC 181
I + GHT V S G + AS D LW N D C
Sbjct: 133 IYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDELHC 176
Score = 70.1 bits (164), Expect = 3e-11
Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
Query: 57 YRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSD 116
Y H V FS G+ + S S DKT++IW T F V F+
Sbjct: 8 YSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPS 67
Query: 117 GSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNL 176
G+ I +A D+ VK+W +K + + H+ V C G+ + + S D + K+ +L
Sbjct: 68 GTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDL 127
Query: 177 DSGECIHTYKDLKGH 191
G I+T L+GH
Sbjct: 128 LEGRLIYT---LQGH 139
Score = 46.0 bits (104), Expect = 6e-04
Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 3/123 (2%)
Query: 230 HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFS 289
H V P G I++ S+D +KI D + S G N V+F+P+G +
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 72
Query: 290 SAGDDKLVFIWKTNFTDLSSESK-ENEGQNMITGQRHLTEEGIDTITENGQIQDVNILSK 348
SAG D+ V +W L + + G N I+ H + + T + +G ++ +++L
Sbjct: 73 SAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCIS--FHPSGNYLITASSDGTLKILDLLEG 130
Query: 349 KAL 351
+ +
Sbjct: 131 RLI 133
>U72342-1|AAC51111.1| 410|Homo sapiens platelet activating factor
acetylhydrolase, brain isoform, 45 kDa subunit protein.
Length = 410
Score = 149 bits (362), Expect = 4e-35
Identities = 82/319 (25%), Positives = 152/319 (47%), Gaps = 20/319 (6%)
Query: 3 EDKVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGH 62
+ K P P K L GH++ +T + ++P + ++S D ++ +WD +GH
Sbjct: 90 DPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGH 149
Query: 63 DEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
++V D++F SGK +AS S D T+++W H V SV +G I++
Sbjct: 150 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 209
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECI 182
AS DK +K+W + +F GH WVR R + DG++IASCS+D++ ++W + + EC
Sbjct: 210 ASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECK 269
Query: 183 HTYKDLKGHGLHLAWHPSGCYVAVATSHGN--------------------VKLYDIRTHN 222
++ + ++W P Y +++ + G+ +K++D+ T
Sbjct: 270 AELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGM 329
Query: 223 LVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFS 282
+ H+ V V H G +IL+ + D +++ D + TL+ H V +++F
Sbjct: 330 CLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFH 389
Query: 283 PTGDTFSSAGDDKLVFIWK 301
T + D+ V +W+
Sbjct: 390 KTAPYVVTGSVDQTVKVWE 408
Score = 101 bits (241), Expect = 2e-20
Identities = 56/225 (24%), Positives = 102/225 (45%), Gaps = 20/225 (8%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ + GH + ++++ PN I ++S D ++ +W+++ F GH E V V +
Sbjct: 186 RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQD 245
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK--------------- 119
G +AS S D+TVR+WV + H V + ++ + S
Sbjct: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
Query: 120 -----IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
+++ S DK +K+W + + VGH NWVR + G I SC+DDK+ ++W
Sbjct: 306 KPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+ + C+ T + L +H + YV + VK+++ R
Sbjct: 366 DYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 79.8 bits (188), Expect = 4e-14
Identities = 41/156 (26%), Positives = 84/156 (53%)
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S++ S S+D + K+W+ ++G+ T K +++ SG +A ++ +KL+D +
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
++ H+ V+ VAI P+G +I++AS+D +K+ ++ G+ + T +GH V V
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 240
Query: 280 NFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENE 315
+ G +S +D+ V +W + +E +E+E
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 149 bits (362), Expect = 4e-35
Identities = 82/319 (25%), Positives = 152/319 (47%), Gaps = 20/319 (6%)
Query: 3 EDKVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGH 62
+ K P P K L GH++ +T + ++P + ++S D ++ +WD +GH
Sbjct: 90 DPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGH 149
Query: 63 DEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
++V D++F SGK +AS S D T+++W H V SV +G I++
Sbjct: 150 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 209
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECI 182
AS DK +K+W + +F GH WVR R + DG++IASCS+D++ ++W + + EC
Sbjct: 210 ASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECK 269
Query: 183 HTYKDLKGHGLHLAWHPSGCYVAVATSHGN--------------------VKLYDIRTHN 222
++ + ++W P Y +++ + G+ +K++D+ T
Sbjct: 270 AELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGM 329
Query: 223 LVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFS 282
+ H+ V V H G +IL+ + D +++ D + TL+ H V +++F
Sbjct: 330 CLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFH 389
Query: 283 PTGDTFSSAGDDKLVFIWK 301
T + D+ V +W+
Sbjct: 390 KTAPYVVTGSVDQTVKVWE 408
Score = 101 bits (241), Expect = 2e-20
Identities = 56/225 (24%), Positives = 102/225 (45%), Gaps = 20/225 (8%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ + GH + ++++ PN I ++S D ++ +W+++ F GH E V V +
Sbjct: 186 RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQD 245
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK--------------- 119
G +AS S D+TVR+WV + H V + ++ + S
Sbjct: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
Query: 120 -----IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
+++ S DK +K+W + + VGH NWVR + G I SC+DDK+ ++W
Sbjct: 306 KPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+ + C+ T + L +H + YV + VK+++ R
Sbjct: 366 DYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 79.8 bits (188), Expect = 4e-14
Identities = 41/156 (26%), Positives = 84/156 (53%)
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S++ S S+D + K+W+ ++G+ T K +++ SG +A ++ +KL+D +
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
++ H+ V+ VAI P+G +I++AS+D +K+ ++ G+ + T +GH V V
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 240
Query: 280 NFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENE 315
+ G +S +D+ V +W + +E +E+E
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 149 bits (362), Expect = 4e-35
Identities = 82/319 (25%), Positives = 152/319 (47%), Gaps = 20/319 (6%)
Query: 3 EDKVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGH 62
+ K P P K L GH++ +T + ++P + ++S D ++ +WD +GH
Sbjct: 90 DPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGH 149
Query: 63 DEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
++V D++F SGK +AS S D T+++W H V SV +G I++
Sbjct: 150 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 209
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECI 182
AS DK +K+W + +F GH WVR R + DG++IASCS+D++ ++W + + EC
Sbjct: 210 ASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECK 269
Query: 183 HTYKDLKGHGLHLAWHPSGCYVAVATSHGN--------------------VKLYDIRTHN 222
++ + ++W P Y +++ + G+ +K++D+ T
Sbjct: 270 AELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGM 329
Query: 223 LVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFS 282
+ H+ V V H G +IL+ + D +++ D + TL+ H V +++F
Sbjct: 330 CLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFH 389
Query: 283 PTGDTFSSAGDDKLVFIWK 301
T + D+ V +W+
Sbjct: 390 KTAPYVVTGSVDQTVKVWE 408
Score = 101 bits (241), Expect = 2e-20
Identities = 56/225 (24%), Positives = 102/225 (45%), Gaps = 20/225 (8%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ + GH + ++++ PN I ++S D ++ +W+++ F GH E V V +
Sbjct: 186 RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQD 245
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK--------------- 119
G +AS S D+TVR+WV + H V + ++ + S
Sbjct: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
Query: 120 -----IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
+++ S DK +K+W + + VGH NWVR + G I SC+DDK+ ++W
Sbjct: 306 KPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+ + C+ T + L +H + YV + VK+++ R
Sbjct: 366 DYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 79.8 bits (188), Expect = 4e-14
Identities = 41/156 (26%), Positives = 84/156 (53%)
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S++ S S+D + K+W+ ++G+ T K +++ SG +A ++ +KL+D +
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
++ H+ V+ VAI P+G +I++AS+D +K+ ++ G+ + T +GH V V
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 240
Query: 280 NFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENE 315
+ G +S +D+ V +W + +E +E+E
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating factor
acetylhydrolase, isoform Ib, alpha subunit 45kDa
protein.
Length = 410
Score = 149 bits (362), Expect = 4e-35
Identities = 82/319 (25%), Positives = 152/319 (47%), Gaps = 20/319 (6%)
Query: 3 EDKVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGH 62
+ K P P K L GH++ +T + ++P + ++S D ++ +WD +GH
Sbjct: 90 DPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGH 149
Query: 63 DEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
++V D++F SGK +AS S D T+++W H V SV +G I++
Sbjct: 150 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 209
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECI 182
AS DK +K+W + +F GH WVR R + DG++IASCS+D++ ++W + + EC
Sbjct: 210 ASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECK 269
Query: 183 HTYKDLKGHGLHLAWHPSGCYVAVATSHGN--------------------VKLYDIRTHN 222
++ + ++W P Y +++ + G+ +K++D+ T
Sbjct: 270 AELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGM 329
Query: 223 LVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFS 282
+ H+ V V H G +IL+ + D +++ D + TL+ H V +++F
Sbjct: 330 CLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFH 389
Query: 283 PTGDTFSSAGDDKLVFIWK 301
T + D+ V +W+
Sbjct: 390 KTAPYVVTGSVDQTVKVWE 408
Score = 101 bits (241), Expect = 2e-20
Identities = 56/225 (24%), Positives = 102/225 (45%), Gaps = 20/225 (8%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ + GH + ++++ PN I ++S D ++ +W+++ F GH E V V +
Sbjct: 186 RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQD 245
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK--------------- 119
G +AS S D+TVR+WV + H V + ++ + S
Sbjct: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
Query: 120 -----IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
+++ S DK +K+W + + VGH NWVR + G I SC+DDK+ ++W
Sbjct: 306 KPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+ + C+ T + L +H + YV + VK+++ R
Sbjct: 366 DYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 79.8 bits (188), Expect = 4e-14
Identities = 41/156 (26%), Positives = 84/156 (53%)
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S++ S S+D + K+W+ ++G+ T K +++ SG +A ++ +KL+D +
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
++ H+ V+ VAI P+G +I++AS+D +K+ ++ G+ + T +GH V V
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 240
Query: 280 NFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENE 315
+ G +S +D+ V +W + +E +E+E
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating factor
acetyl hydrolase isoform Ib alpha subunit protein.
Length = 410
Score = 149 bits (362), Expect = 4e-35
Identities = 82/319 (25%), Positives = 152/319 (47%), Gaps = 20/319 (6%)
Query: 3 EDKVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGH 62
+ K P P K L GH++ +T + ++P + ++S D ++ +WD +GH
Sbjct: 90 DPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGH 149
Query: 63 DEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
++V D++F SGK +AS S D T+++W H V SV +G I++
Sbjct: 150 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 209
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECI 182
AS DK +K+W + +F GH WVR R + DG++IASCS+D++ ++W + + EC
Sbjct: 210 ASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECK 269
Query: 183 HTYKDLKGHGLHLAWHPSGCYVAVATSHGN--------------------VKLYDIRTHN 222
++ + ++W P Y +++ + G+ +K++D+ T
Sbjct: 270 AELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGM 329
Query: 223 LVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFS 282
+ H+ V V H G +IL+ + D +++ D + TL+ H V +++F
Sbjct: 330 CLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFH 389
Query: 283 PTGDTFSSAGDDKLVFIWK 301
T + D+ V +W+
Sbjct: 390 KTAPYVVTGSVDQTVKVWE 408
Score = 101 bits (241), Expect = 2e-20
Identities = 56/225 (24%), Positives = 102/225 (45%), Gaps = 20/225 (8%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ + GH + ++++ PN I ++S D ++ +W+++ F GH E V V +
Sbjct: 186 RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQD 245
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK--------------- 119
G +AS S D+TVR+WV + H V + ++ + S
Sbjct: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
Query: 120 -----IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
+++ S DK +K+W + + VGH NWVR + G I SC+DDK+ ++W
Sbjct: 306 KPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+ + C+ T + L +H + YV + VK+++ R
Sbjct: 366 DYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 79.8 bits (188), Expect = 4e-14
Identities = 41/156 (26%), Positives = 84/156 (53%)
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S++ S S+D + K+W+ ++G+ T K +++ SG +A ++ +KL+D +
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
++ H+ V+ VAI P+G +I++AS+D +K+ ++ G+ + T +GH V V
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 240
Query: 280 NFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENE 315
+ G +S +D+ V +W + +E +E+E
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 149 bits (362), Expect = 4e-35
Identities = 82/319 (25%), Positives = 152/319 (47%), Gaps = 20/319 (6%)
Query: 3 EDKVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGH 62
+ K P P K L GH++ +T + ++P + ++S D ++ +WD +GH
Sbjct: 90 DPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGH 149
Query: 63 DEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
++V D++F SGK +AS S D T+++W H V SV +G I++
Sbjct: 150 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVS 209
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECI 182
AS DK +K+W + +F GH WVR R + DG++IASCS+D++ ++W + + EC
Sbjct: 210 ASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECK 269
Query: 183 HTYKDLKGHGLHLAWHPSGCYVAVATSHGN--------------------VKLYDIRTHN 222
++ + ++W P Y +++ + G+ +K++D+ T
Sbjct: 270 AELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGM 329
Query: 223 LVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFS 282
+ H+ V V H G +IL+ + D +++ D + TL+ H V +++F
Sbjct: 330 CLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFH 389
Query: 283 PTGDTFSSAGDDKLVFIWK 301
T + D+ V +W+
Sbjct: 390 KTAPYVVTGSVDQTVKVWE 408
Score = 101 bits (241), Expect = 2e-20
Identities = 56/225 (24%), Positives = 102/225 (45%), Gaps = 20/225 (8%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ + GH + ++++ PN I ++S D ++ +W+++ F GH E V V +
Sbjct: 186 RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQD 245
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK--------------- 119
G +AS S D+TVR+WV + H V + ++ + S
Sbjct: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
Query: 120 -----IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
+++ S DK +K+W + + VGH NWVR + G I SC+DDK+ ++W
Sbjct: 306 KPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+ + C+ T + L +H + YV + VK+++ R
Sbjct: 366 DYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 79.8 bits (188), Expect = 4e-14
Identities = 41/156 (26%), Positives = 84/156 (53%)
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S++ S S+D + K+W+ ++G+ T K +++ SG +A ++ +KL+D +
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
++ H+ V+ VAI P+G +I++AS+D +K+ ++ G+ + T +GH V V
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 240
Query: 280 NFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENE 315
+ G +S +D+ V +W + +E +E+E
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69
protein.
Length = 415
Score = 144 bits (348), Expect = 2e-33
Identities = 74/286 (25%), Positives = 139/286 (48%), Gaps = 1/286 (0%)
Query: 17 LKGHKNAITALYYN-PNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
L+GH+N + A+ +N P +IAT S D + LW + + F+GH ++ ++F+
Sbjct: 130 LEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQS 189
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+A+ S D T ++W + HS + S+ F++ G +IIT S D V +W
Sbjct: 190 TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDAD 249
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL 195
+ ++ +GH + A + D S+I + S DK+ KLW+ +G+C+ T L
Sbjct: 250 TGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDS 309
Query: 196 AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKM 255
+ +G +A A++ G +++ T + H +++++ +P G+++LT S D
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTA 369
Query: 256 KILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
+I D G + L GH + + F+ G+ + D IW+
Sbjct: 370 RIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR 415
Score = 107 bits (258), Expect = 1e-22
Identities = 66/259 (25%), Positives = 118/259 (45%), Gaps = 1/259 (0%)
Query: 60 QGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSD-GS 118
+ H + +V + SG + S D+T ++W + H V ++ F++ G
Sbjct: 89 KAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGD 148
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
KI T S DK KLWS K +F GHT + C + +++A+ S D + KLW++ +
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQN 208
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
GE ++T + + L+++ SG + + V ++D T V H ++ +
Sbjct: 209 GEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSAS 268
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVF 298
+ S ILT S D K+ D G + TL+GH+ + F TG ++A D
Sbjct: 269 FNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTAR 328
Query: 299 IWKTNFTDLSSESKENEGQ 317
I+ ++ + +EG+
Sbjct: 329 IFSAATRKCIAKLEGHEGE 347
Score = 107 bits (256), Expect = 2e-22
Identities = 70/292 (23%), Positives = 122/292 (41%), Gaps = 7/292 (2%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L K LK H +T + N + T S D + LWD +GH V + F+
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 73 SS-GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+ G +A+ S DKT ++W F+ H+ + + F+ + + T S D KL
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + + GH+ + + G I + S D + +W+ D+G ++ L GH
Sbjct: 204 WDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNI---LIGH 260
Query: 192 GLHL---AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILT 248
+ +++ + + KL+D V + H++ + +G I T
Sbjct: 261 CAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIAT 320
Query: 249 ASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
AS DG +I I L GH G ++ ++F+P G+ + DK IW
Sbjct: 321 ASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIW 372
Score = 54.8 bits (126), Expect = 1e-06
Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
C+ K L+GH+ I+ + +NP + T S D + +WD + +GH + + F
Sbjct: 337 CIAK-LEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAF 395
Query: 72 SSSGKYMASASRDKTVRIW 90
+ G + + S+D T RIW
Sbjct: 396 NYKGNIVITGSKDNTCRIW 414
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
T L + H +T VA++ SGS +T S D K+ D G + TL GH V A+
Sbjct: 81 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAI 140
Query: 280 NF-SPTGDTFSSAGDDKLVFIW 300
F +P GD ++ DK +W
Sbjct: 141 AFNNPYGDKIATGSFDKTCKLW 162
>AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ40090 fis, clone TESTI2003596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 415
Score = 144 bits (348), Expect = 2e-33
Identities = 74/286 (25%), Positives = 139/286 (48%), Gaps = 1/286 (0%)
Query: 17 LKGHKNAITALYYN-PNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
L+GH+N + A+ +N P +IAT S D + LW + + F+GH ++ ++F+
Sbjct: 130 LEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQS 189
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+A+ S D T ++W + HS + S+ F++ G +IIT S D V +W
Sbjct: 190 TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDAD 249
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL 195
+ ++ +GH + A + D S+I + S DK+ KLW+ +G+C+ T L
Sbjct: 250 TGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDS 309
Query: 196 AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKM 255
+ +G +A A++ G +++ T + H +++++ +P G+++LT S D
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTA 369
Query: 256 KILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
+I D G + L GH + + F+ G+ + D IW+
Sbjct: 370 RIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR 415
Score = 107 bits (258), Expect = 1e-22
Identities = 66/259 (25%), Positives = 118/259 (45%), Gaps = 1/259 (0%)
Query: 60 QGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSD-GS 118
+ H + +V + SG + S D+T ++W + H V ++ F++ G
Sbjct: 89 KAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGD 148
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
KI T S DK KLWS K +F GHT + C + +++A+ S D + KLW++ +
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQN 208
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
GE ++T + + L+++ SG + + V ++D T V H ++ +
Sbjct: 209 GEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSAS 268
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVF 298
+ S ILT S D K+ D G + TL+GH+ + F TG ++A D
Sbjct: 269 FNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTAR 328
Query: 299 IWKTNFTDLSSESKENEGQ 317
I+ ++ + +EG+
Sbjct: 329 IFSAATRKCIAKLEGHEGE 347
Score = 107 bits (256), Expect = 2e-22
Identities = 70/292 (23%), Positives = 122/292 (41%), Gaps = 7/292 (2%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L K LK H +T + N + T S D + LWD +GH V + F+
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 73 SS-GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+ G +A+ S DKT ++W F+ H+ + + F+ + + T S D KL
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + + GH+ + + G I + S D + +W+ D+G ++ L GH
Sbjct: 204 WDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNI---LIGH 260
Query: 192 GLHL---AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILT 248
+ +++ + + KL+D V + H++ + +G I T
Sbjct: 261 CAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIAT 320
Query: 249 ASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
AS DG +I I L GH G ++ ++F+P G+ + DK IW
Sbjct: 321 ASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIW 372
Score = 54.8 bits (126), Expect = 1e-06
Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
C+ K L+GH+ I+ + +NP + T S D + +WD + +GH + + F
Sbjct: 337 CIAK-LEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAF 395
Query: 72 SSSGKYMASASRDKTVRIW 90
+ G + + S+D T RIW
Sbjct: 396 NYKGNIVITGSKDNTCRIW 414
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
T L + H +T VA++ SGS +T S D K+ D G + TL GH V A+
Sbjct: 81 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAI 140
Query: 280 NF-SPTGDTFSSAGDDKLVFIW 300
F +P GD ++ DK +W
Sbjct: 141 AFNNPYGDKIATGSFDKTCKLW 162
>AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein.
Length = 415
Score = 144 bits (348), Expect = 2e-33
Identities = 74/286 (25%), Positives = 139/286 (48%), Gaps = 1/286 (0%)
Query: 17 LKGHKNAITALYYN-PNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
L+GH+N + A+ +N P +IAT S D + LW + + F+GH ++ ++F+
Sbjct: 130 LEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQS 189
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+A+ S D T ++W + HS + S+ F++ G +IIT S D V +W
Sbjct: 190 TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDAD 249
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL 195
+ ++ +GH + A + D S+I + S DK+ KLW+ +G+C+ T L
Sbjct: 250 TGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDS 309
Query: 196 AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKM 255
+ +G +A A++ G +++ T + H +++++ +P G+++LT S D
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTA 369
Query: 256 KILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
+I D G + L GH + + F+ G+ + D IW+
Sbjct: 370 RIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR 415
Score = 107 bits (258), Expect = 1e-22
Identities = 66/259 (25%), Positives = 118/259 (45%), Gaps = 1/259 (0%)
Query: 60 QGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSD-GS 118
+ H + +V + SG + S D+T ++W + H V ++ F++ G
Sbjct: 89 KAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGD 148
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
KI T S DK KLWS K +F GHT + C + +++A+ S D + KLW++ +
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQN 208
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
GE ++T + + L+++ SG + + V ++D T V H ++ +
Sbjct: 209 GEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSAS 268
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVF 298
+ S ILT S D K+ D G + TL+GH+ + F TG ++A D
Sbjct: 269 FNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTAR 328
Query: 299 IWKTNFTDLSSESKENEGQ 317
I+ ++ + +EG+
Sbjct: 329 IFSAATRKCIAKLEGHEGE 347
Score = 107 bits (256), Expect = 2e-22
Identities = 70/292 (23%), Positives = 122/292 (41%), Gaps = 7/292 (2%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L K LK H +T + N + T S D + LWD +GH V + F+
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 73 SS-GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+ G +A+ S DKT ++W F+ H+ + + F+ + + T S D KL
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + + GH+ + + G I + S D + +W+ D+G ++ L GH
Sbjct: 204 WDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNI---LIGH 260
Query: 192 GLHL---AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILT 248
+ +++ + + KL+D V + H++ + +G I T
Sbjct: 261 CAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIAT 320
Query: 249 ASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
AS DG +I I L GH G ++ ++F+P G+ + DK IW
Sbjct: 321 ASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIW 372
Score = 54.8 bits (126), Expect = 1e-06
Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
C+ K L+GH+ I+ + +NP + T S D + +WD + +GH + + F
Sbjct: 337 CIAK-LEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAF 395
Query: 72 SSSGKYMASASRDKTVRIW 90
+ G + + S+D T RIW
Sbjct: 396 NYKGNIVITGSKDNTCRIW 414
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
T L + H +T VA++ SGS +T S D K+ D G + TL GH V A+
Sbjct: 81 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAI 140
Query: 280 NF-SPTGDTFSSAGDDKLVFIW 300
F +P GD ++ DK +W
Sbjct: 141 AFNNPYGDKIATGSFDKTCKLW 162
>AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 143 bits (347), Expect = 2e-33
Identities = 80/313 (25%), Positives = 149/313 (47%), Gaps = 20/313 (6%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P P K L GH++ +T + ++P + ++S D ++ +WD +GH ++V D
Sbjct: 96 PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQD 155
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
++F SGK +AS S D T+++ H V SV +G I++AS DK
Sbjct: 156 ISFDHSGKLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKT 215
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+K+W + +F GH WVR R + DG++IASCS+D++ ++W + + EC ++
Sbjct: 216 IKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREH 275
Query: 189 KGHGLHLAWHPSGCYVAVATSHGN--------------------VKLYDIRTHNLVQYYS 228
+ ++W P Y +++ + G+ +K++D+ T +
Sbjct: 276 EHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV 335
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTF 288
H+ V V H G +IL+ + D +++ D + TL+ H V +++F T
Sbjct: 336 GHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYV 395
Query: 289 SSAGDDKLVFIWK 301
+ D+ V +W+
Sbjct: 396 VTGSVDQTVKVWE 408
Score = 101 bits (241), Expect = 2e-20
Identities = 56/225 (24%), Positives = 102/225 (45%), Gaps = 20/225 (8%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ + GH + ++++ PN I ++S D ++ +W+++ F GH E V V +
Sbjct: 186 RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQD 245
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK--------------- 119
G +AS S D+TVR+WV + H V + ++ + S
Sbjct: 246 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 305
Query: 120 -----IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
+++ S DK +K+W + + VGH NWVR + G I SC+DDK+ ++W
Sbjct: 306 KPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+ + C+ T + L +H + YV + VK+++ R
Sbjct: 366 DYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
Score = 81.0 bits (191), Expect = 2e-14
Identities = 50/204 (24%), Positives = 95/204 (46%), Gaps = 2/204 (0%)
Query: 90 WVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNW 149
W+P + H V V F S +++AS+D +K+W F + GHT+
Sbjct: 94 WIPRPPEKYAL-SGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS 152
Query: 150 VRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATS 209
V+ + G ++ASCS D + KL + ECI T + +A P+G ++ A+
Sbjct: 153 VQDISFDHSGKLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASR 212
Query: 210 HGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTL 269
+K+++++T V+ ++ H E V V + G+ I + S D +++ + L
Sbjct: 213 DKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272
Query: 270 SGHNGPVNAVNFSPTGDTFSSAGD 293
H V ++++P ++SS +
Sbjct: 273 REHEHVVECISWAPE-SSYSSISE 295
Score = 78.2 bits (184), Expect = 1e-13
Identities = 41/156 (26%), Positives = 83/156 (53%)
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S++ S S+D + K+W+ ++G+ T K +++ SG +A ++ +KL D +
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLRDFQ 180
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
++ H+ V+ VAI P+G +I++AS+D +K+ ++ G+ + T +GH V V
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV 240
Query: 280 NFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENE 315
+ G +S +D+ V +W + +E +E+E
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>BC060876-1|AAH60876.1| 650|Homo sapiens tudor domain containing 3
protein.
Length = 650
Score = 142 bits (344), Expect = 5e-33
Identities = 119/380 (31%), Positives = 180/380 (47%), Gaps = 72/380 (18%)
Query: 403 MLKLTLHDGKVTCTGLEISHIPSLSINTPPGTKLLLKNEELEVCHGVVWLTPSVISVLGG 462
ML+L + DG ++CT +E S++ +S+NTPPGTK+ L +++ +G + L S +VLGG
Sbjct: 1 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGI-VDIKNGFLLLNDSNTTVLGG 59
Query: 463 TVSHMIEKWELNRSLAKHTRGGIGAEGGPPPWIPFGQRLEALSVDK----QFKSLQEA-- 516
V H+IEKWEL RSL+KH R IG EGGPPP++PFGQ + + VD + K+LQ
Sbjct: 60 EVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQCVSRVQVDSRELDRRKTLQVTMP 119
Query: 517 --AKQDNPEFEAQRKGAIAEAQRMS-----GVFGGGTKPLLDANV------QKIVDAGFT 563
DN EFE QR AIAE + G GGG + L+ N + + T
Sbjct: 120 VKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKST 179
Query: 564 EEQAEATLKYTKNNVDRALKILQK------------RDNSEN----------RNKEKP-- 599
+ + + Y + ++ALK + + DN N NK+KP
Sbjct: 180 KSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVM 239
Query: 600 -QKEQDPVKRKGRHKESGDEDGVPVKPSGKVSLFDFLEDKLPNVPEKDKNTRQNNSSMED 658
+ K +GR + +ED +PS +LFDFLE K+ + N + S +
Sbjct: 240 GPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTL-----NVEEPKSQPQQ 294
Query: 659 RYDXXXXXXXXXXXXXXXXXHEGANRNRSDRRHYSNDNLYSSY--REDRKYQSQNEKPPR 716
H+G R+ + ++ DN + + R D + Q +NEKPPR
Sbjct: 295 -------------------LHQGQYRSSNTEQNGVKDNNHLRHPPRNDTR-QPRNEKPPR 334
Query: 717 FQKIQEEMNKHHQNMNMPYN 736
FQ+ + + +P N
Sbjct: 335 FQRDSQNSKSVLEGSGLPRN 354
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/52 (61%), Positives = 35/52 (67%), Gaps = 2/52 (3%)
Query: 904 WKVGDRCLALYWEDNNFYEAEITGV--SANTVVVKFCAYGNHEEVLKSNCLP 953
WK GD C ALYWEDN FY AE+ + S T VVKF YGN+EEVL SN P
Sbjct: 555 WKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKP 606
>AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ25955 fis, clone TST03904. ).
Length = 415
Score = 141 bits (341), Expect = 1e-32
Identities = 73/286 (25%), Positives = 138/286 (48%), Gaps = 1/286 (0%)
Query: 17 LKGHKNAITALYYN-PNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
L+GH+N + A+ +N P +IAT S D + LW + + F+GH ++ ++F+
Sbjct: 130 LEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQS 189
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+A+ S D T ++W + HS + S+ F++ G +IIT S D V +W
Sbjct: 190 TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDAD 249
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL 195
+ ++ +GH + A + D S+I + S DK+ KLW+ +G+C+ T L
Sbjct: 250 TGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDS 309
Query: 196 AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKM 255
+ +G +A A++ G +++ T + H +++++ +P G+++LT S D
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTA 369
Query: 256 KILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
+I D G + L GH + + F+ G+ + IW+
Sbjct: 370 RIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKGNTCRIWR 415
Score = 107 bits (258), Expect = 1e-22
Identities = 66/259 (25%), Positives = 118/259 (45%), Gaps = 1/259 (0%)
Query: 60 QGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSD-GS 118
+ H + +V + SG + S D+T ++W + H V ++ F++ G
Sbjct: 89 KAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGD 148
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
KI T S DK KLWS K +F GHT + C + +++A+ S D + KLW++ +
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQN 208
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
GE ++T + + L+++ SG + + V ++D T V H ++ +
Sbjct: 209 GEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSAS 268
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVF 298
+ S ILT S D K+ D G + TL+GH+ + F TG ++A D
Sbjct: 269 FNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTAR 328
Query: 299 IWKTNFTDLSSESKENEGQ 317
I+ ++ + +EG+
Sbjct: 329 IFSAATRKCIAKLEGHEGE 347
Score = 106 bits (255), Expect = 3e-22
Identities = 70/292 (23%), Positives = 122/292 (41%), Gaps = 7/292 (2%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L K LK H +T + N + T S D + LWD +GH V + F+
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFN 143
Query: 73 SS-GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+ G +A+ S DKT ++W F+ H+ + + F+ + + T S D KL
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + + GH+ + + G I + S D + +W+ D+G ++ L GH
Sbjct: 204 WDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNI---LIGH 260
Query: 192 GLHL---AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILT 248
+ +++ + + KL+D V + H++ + +G I T
Sbjct: 261 CAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIAT 320
Query: 249 ASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
AS DG +I I L GH G ++ ++F+P G+ + DK IW
Sbjct: 321 ASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIW 372
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
C+ K L+GH+ I+ + +NP + T S D + +WD + +GH + + F
Sbjct: 337 CIAK-LEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAF 395
Query: 72 SSSGKYMASASRDKTVRIW 90
+ G + + S+ T RIW
Sbjct: 396 NYKGNIVITGSKGNTCRIW 414
Score = 49.6 bits (113), Expect = 5e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
T L + H +T VA++ SGS +T S D K+ D G + TL GH V A+
Sbjct: 81 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAI 140
Query: 280 NF-SPTGDTFSSAGDDKLVFIW 300
F +P GD ++ DK +W
Sbjct: 141 AFNNPYGDKIATGSFDKTCKLW 162
>BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 139 bits (337), Expect = 4e-32
Identities = 85/301 (28%), Positives = 145/301 (48%), Gaps = 6/301 (1%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P LK L GH A++++ ++PN + +A+SS D + +W GH + D
Sbjct: 33 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISD 92
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V +SS + SAS DKT++IW + K HS V F+ + I++ S D+
Sbjct: 93 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES 152
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
V++W K + + H++ V + DGS+I S S D ++W+ SG+C+ T D
Sbjct: 153 VRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD 212
Query: 189 KGHGL-HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH-NEAVTQVAIH--PSGS 244
+ + + P+G Y+ AT +KL+D ++ Y+ H NE A G
Sbjct: 213 DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK 272
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG--DDKLVFIWKT 302
+I++ S+D + I +L + L GH V + PT + +SA +DK + +WK+
Sbjct: 273 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 332
Query: 303 N 303
+
Sbjct: 333 D 333
Score = 54.8 bits (126), Expect = 1e-06
Identities = 35/133 (26%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-RG-TMRSYRFQGHDE 64
T CLK + ++ + ++PN + I ++LDN++ LWD +G +++Y +++
Sbjct: 200 TASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEK 259
Query: 65 AVMDVTFS-SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITA 123
+ FS + GK++ S S D V IW + H+ V S + I +A
Sbjct: 260 YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASA 319
Query: 124 S--DDKVVKLWST 134
+ +DK +KLW +
Sbjct: 320 ALENDKTIKLWKS 332
>BX537910-1|CAD97894.1| 651|Homo sapiens hypothetical protein
protein.
Length = 651
Score = 139 bits (337), Expect = 4e-32
Identities = 119/381 (31%), Positives = 181/381 (47%), Gaps = 73/381 (19%)
Query: 403 MLKLTLHDGKVTCTGLEISHIPSLSINTPPGTKLLLKNEELEVCHGVVWLTPSVISVLGG 462
ML+L + DG ++CT +E S++ +S+NTPPGTK+ L +++ +G + L S +VLGG
Sbjct: 1 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGI-VDIKNGFLLLNDSNTTVLGG 59
Query: 463 TVSHMIEKWELNRSLAKHTRGGIGAEGGPPPWIPFGQR-LEALSVDK----QFKSLQEA- 516
V H+IEKWEL RSL+KH R IG EGGPPP++PFGQ+ + + VD + K+LQ
Sbjct: 60 EVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTM 119
Query: 517 ---AKQDNPEFEAQRKGAIAEAQRMS-----GVFGGGTKPLLDANV------QKIVDAGF 562
DN EFE QR AIAE + G GGG + L+ N + +
Sbjct: 120 PVKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKS 179
Query: 563 TEEQAEATLKYTKNNVDRALKILQK------------RDNSEN----------RNKEKP- 599
T+ + + Y + ++ALK + + DN N NK+KP
Sbjct: 180 TKSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPV 239
Query: 600 --QKEQDPVKRKGRHKESGDEDGVPVKPSGKVSLFDFLEDKLPNVPEKDKNTRQNNSSME 657
+ K +GR + +ED +PS +LFDFLE K+ + N + S +
Sbjct: 240 MGPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTL-----NVEEPKSQPQ 294
Query: 658 DRYDXXXXXXXXXXXXXXXXXHEGANRNRSDRRHYSNDNLYSSY--REDRKYQSQNEKPP 715
H+G R+ + ++ DN + + R D + Q +NEKPP
Sbjct: 295 Q-------------------LHQGQYRSSNTEQNGVKDNNHLRHPPRNDTR-QPRNEKPP 334
Query: 716 RFQKIQEEMNKHHQNMNMPYN 736
RFQ+ + + +P N
Sbjct: 335 RFQRDSQNSKSVLEGSGLPRN 355
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/52 (61%), Positives = 35/52 (67%), Gaps = 2/52 (3%)
Query: 904 WKVGDRCLALYWEDNNFYEAEITGV--SANTVVVKFCAYGNHEEVLKSNCLP 953
WK GD C ALYWEDN FY AE+ + S T VVKF YGN+EEVL SN P
Sbjct: 556 WKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKP 607
>BC030514-1|AAH30514.1| 651|Homo sapiens tudor domain containing 3
protein.
Length = 651
Score = 139 bits (337), Expect = 4e-32
Identities = 119/381 (31%), Positives = 181/381 (47%), Gaps = 73/381 (19%)
Query: 403 MLKLTLHDGKVTCTGLEISHIPSLSINTPPGTKLLLKNEELEVCHGVVWLTPSVISVLGG 462
ML+L + DG ++CT +E S++ +S+NTPPGTK+ L +++ +G + L S +VLGG
Sbjct: 1 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGI-VDIKNGFLLLNDSNTTVLGG 59
Query: 463 TVSHMIEKWELNRSLAKHTRGGIGAEGGPPPWIPFGQR-LEALSVDK----QFKSLQEA- 516
V H+IEKWEL RSL+KH R IG EGGPPP++PFGQ+ + + VD + K+LQ
Sbjct: 60 EVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTM 119
Query: 517 ---AKQDNPEFEAQRKGAIAEAQRMS-----GVFGGGTKPLLDANV------QKIVDAGF 562
DN EFE QR AIAE + G GGG + L+ N + +
Sbjct: 120 PVKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKS 179
Query: 563 TEEQAEATLKYTKNNVDRALKILQK------------RDNSEN----------RNKEKP- 599
T+ + + Y + ++ALK + + DN N NK+KP
Sbjct: 180 TKSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPV 239
Query: 600 --QKEQDPVKRKGRHKESGDEDGVPVKPSGKVSLFDFLEDKLPNVPEKDKNTRQNNSSME 657
+ K +GR + +ED +PS +LFDFLE K+ + N + S +
Sbjct: 240 MGPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTL-----NVEEPKSQPQ 294
Query: 658 DRYDXXXXXXXXXXXXXXXXXHEGANRNRSDRRHYSNDNLYSSY--REDRKYQSQNEKPP 715
H+G R+ + ++ DN + + R D + Q +NEKPP
Sbjct: 295 Q-------------------LHQGQYRSSNTEQNGVKDNNHLRHPPRNDTR-QPRNEKPP 334
Query: 716 RFQKIQEEMNKHHQNMNMPYN 736
RFQ+ + + +P N
Sbjct: 335 RFQRDSQNSKSVLEGSGLPRN 355
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/52 (61%), Positives = 35/52 (67%), Gaps = 2/52 (3%)
Query: 904 WKVGDRCLALYWEDNNFYEAEITGV--SANTVVVKFCAYGNHEEVLKSNCLP 953
WK GD C ALYWEDN FY AE+ + S T VVKF YGN+EEVL SN P
Sbjct: 556 WKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKP 607
>BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 139 bits (337), Expect = 4e-32
Identities = 85/301 (28%), Positives = 145/301 (48%), Gaps = 6/301 (1%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P LK L GH A++++ ++PN + +A+SS D + +W GH + D
Sbjct: 33 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISD 92
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V +SS + SAS DKT++IW + K HS V F+ + I++ S D+
Sbjct: 93 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES 152
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
V++W K + + H++ V + DGS+I S S D ++W+ SG+C+ T D
Sbjct: 153 VRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD 212
Query: 189 KGHGL-HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH-NEAVTQVAIH--PSGS 244
+ + + P+G Y+ AT +KL+D ++ Y+ H NE A G
Sbjct: 213 DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK 272
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG--DDKLVFIWKT 302
+I++ S+D + I +L + L GH V + PT + +SA +DK + +WK+
Sbjct: 273 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 332
Query: 303 N 303
+
Sbjct: 333 D 333
Score = 54.8 bits (126), Expect = 1e-06
Identities = 35/133 (26%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-RG-TMRSYRFQGHDE 64
T CLK + ++ + ++PN + I ++LDN++ LWD +G +++Y +++
Sbjct: 200 TASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEK 259
Query: 65 AVMDVTFS-SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITA 123
+ FS + GK++ S S D V IW + H+ V S + I +A
Sbjct: 260 YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASA 319
Query: 124 S--DDKVVKLWST 134
+ +DK +KLW +
Sbjct: 320 ALENDKTIKLWKS 332
>AL512666-2|CAH74000.1| 651|Homo sapiens tudor domain containing 3
protein.
Length = 651
Score = 139 bits (337), Expect = 4e-32
Identities = 119/381 (31%), Positives = 181/381 (47%), Gaps = 73/381 (19%)
Query: 403 MLKLTLHDGKVTCTGLEISHIPSLSINTPPGTKLLLKNEELEVCHGVVWLTPSVISVLGG 462
ML+L + DG ++CT +E S++ +S+NTPPGTK+ L +++ +G + L S +VLGG
Sbjct: 1 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGI-VDIKNGFLLLNDSNTTVLGG 59
Query: 463 TVSHMIEKWELNRSLAKHTRGGIGAEGGPPPWIPFGQR-LEALSVDK----QFKSLQEA- 516
V H+IEKWEL RSL+KH R IG EGGPPP++PFGQ+ + + VD + K+LQ
Sbjct: 60 EVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTM 119
Query: 517 ---AKQDNPEFEAQRKGAIAEAQRMS-----GVFGGGTKPLLDANV------QKIVDAGF 562
DN EFE QR AIAE + G GGG + L+ N + +
Sbjct: 120 PVKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKS 179
Query: 563 TEEQAEATLKYTKNNVDRALKILQK------------RDNSEN----------RNKEKP- 599
T+ + + Y + ++ALK + + DN N NK+KP
Sbjct: 180 TKSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPV 239
Query: 600 --QKEQDPVKRKGRHKESGDEDGVPVKPSGKVSLFDFLEDKLPNVPEKDKNTRQNNSSME 657
+ K +GR + +ED +PS +LFDFLE K+ + N + S +
Sbjct: 240 MGPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTL-----NVEEPKSQPQ 294
Query: 658 DRYDXXXXXXXXXXXXXXXXXHEGANRNRSDRRHYSNDNLYSSY--REDRKYQSQNEKPP 715
H+G R+ + ++ DN + + R D + Q +NEKPP
Sbjct: 295 Q-------------------LHQGQYRSSNTEQNGVKDNNHLRHPPRNDTR-QPRNEKPP 334
Query: 716 RFQKIQEEMNKHHQNMNMPYN 736
RFQ+ + + +P N
Sbjct: 335 RFQRDSQNSKSVLEGSGLPRN 355
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/52 (61%), Positives = 35/52 (67%), Gaps = 2/52 (3%)
Query: 904 WKVGDRCLALYWEDNNFYEAEITGV--SANTVVVKFCAYGNHEEVLKSNCLP 953
WK GD C ALYWEDN FY AE+ + S T VVKF YGN+EEVL SN P
Sbjct: 556 WKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKP 607
>AL354764-2|CAH72281.1| 651|Homo sapiens tudor domain containing 3
protein.
Length = 651
Score = 139 bits (337), Expect = 4e-32
Identities = 119/381 (31%), Positives = 181/381 (47%), Gaps = 73/381 (19%)
Query: 403 MLKLTLHDGKVTCTGLEISHIPSLSINTPPGTKLLLKNEELEVCHGVVWLTPSVISVLGG 462
ML+L + DG ++CT +E S++ +S+NTPPGTK+ L +++ +G + L S +VLGG
Sbjct: 1 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGI-VDIKNGFLLLNDSNTTVLGG 59
Query: 463 TVSHMIEKWELNRSLAKHTRGGIGAEGGPPPWIPFGQR-LEALSVDK----QFKSLQEA- 516
V H+IEKWEL RSL+KH R IG EGGPPP++PFGQ+ + + VD + K+LQ
Sbjct: 60 EVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTM 119
Query: 517 ---AKQDNPEFEAQRKGAIAEAQRMS-----GVFGGGTKPLLDANV------QKIVDAGF 562
DN EFE QR AIAE + G GGG + L+ N + +
Sbjct: 120 PVKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKS 179
Query: 563 TEEQAEATLKYTKNNVDRALKILQK------------RDNSEN----------RNKEKP- 599
T+ + + Y + ++ALK + + DN N NK+KP
Sbjct: 180 TKSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPV 239
Query: 600 --QKEQDPVKRKGRHKESGDEDGVPVKPSGKVSLFDFLEDKLPNVPEKDKNTRQNNSSME 657
+ K +GR + +ED +PS +LFDFLE K+ + N + S +
Sbjct: 240 MGPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTL-----NVEEPKSQPQ 294
Query: 658 DRYDXXXXXXXXXXXXXXXXXHEGANRNRSDRRHYSNDNLYSSY--REDRKYQSQNEKPP 715
H+G R+ + ++ DN + + R D + Q +NEKPP
Sbjct: 295 Q-------------------LHQGQYRSSNTEQNGVKDNNHLRHPPRNDTR-QPRNEKPP 334
Query: 716 RFQKIQEEMNKHHQNMNMPYN 736
RFQ+ + + +P N
Sbjct: 335 RFQRDSQNSKSVLEGSGLPRN 355
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/52 (61%), Positives = 35/52 (67%), Gaps = 2/52 (3%)
Query: 904 WKVGDRCLALYWEDNNFYEAEITGV--SANTVVVKFCAYGNHEEVLKSNCLP 953
WK GD C ALYWEDN FY AE+ + S T VVKF YGN+EEVL SN P
Sbjct: 556 WKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKP 607
>AK024660-1|BAB14950.1| 651|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21007 fis, clone CAE03871. ).
Length = 651
Score = 139 bits (337), Expect = 4e-32
Identities = 119/381 (31%), Positives = 181/381 (47%), Gaps = 73/381 (19%)
Query: 403 MLKLTLHDGKVTCTGLEISHIPSLSINTPPGTKLLLKNEELEVCHGVVWLTPSVISVLGG 462
ML+L + DG ++CT +E S++ +S+NTPPGTK+ L +++ +G + L S +VLGG
Sbjct: 1 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGI-VDIKNGFLLLNDSNTTVLGG 59
Query: 463 TVSHMIEKWELNRSLAKHTRGGIGAEGGPPPWIPFGQR-LEALSVDK----QFKSLQEA- 516
V H+IEKWEL RSL+KH R IG EGGPPP++PFGQ+ + + VD + K+LQ
Sbjct: 60 EVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTM 119
Query: 517 ---AKQDNPEFEAQRKGAIAEAQRMS-----GVFGGGTKPLLDANV------QKIVDAGF 562
DN EFE QR AIAE + G GGG + L+ N + +
Sbjct: 120 PVKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKS 179
Query: 563 TEEQAEATLKYTKNNVDRALKILQK------------RDNSEN----------RNKEKP- 599
T+ + + Y + ++ALK + + DN N NK+KP
Sbjct: 180 TKSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPV 239
Query: 600 --QKEQDPVKRKGRHKESGDEDGVPVKPSGKVSLFDFLEDKLPNVPEKDKNTRQNNSSME 657
+ K +GR + +ED +PS +LFDFLE K+ + N + S +
Sbjct: 240 MGPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTL-----NVEEPKSQPQ 294
Query: 658 DRYDXXXXXXXXXXXXXXXXXHEGANRNRSDRRHYSNDNLYSSY--REDRKYQSQNEKPP 715
H+G R+ + ++ DN + + R D + Q +NEKPP
Sbjct: 295 Q-------------------LHQGQYRSSNTEQNGVKDNNHLRHPPRNDTR-QPRNEKPP 334
Query: 716 RFQKIQEEMNKHHQNMNMPYN 736
RFQ+ + + +P N
Sbjct: 335 RFQRDSQNSKSVLEGSGLPRN 355
Score = 70.1 bits (164), Expect = 3e-11
Identities = 32/52 (61%), Positives = 35/52 (67%), Gaps = 2/52 (3%)
Query: 904 WKVGDRCLALYWEDNNFYEAEITGV--SANTVVVKFCAYGNHEEVLKSNCLP 953
WK GD C ALYWEDN FY AE+ + S T VVKF YGN+EEVL SN P
Sbjct: 556 WKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKP 607
>AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens
cDNA FLJ20545 fis, clone KAT11476. ).
Length = 334
Score = 139 bits (337), Expect = 4e-32
Identities = 85/301 (28%), Positives = 145/301 (48%), Gaps = 6/301 (1%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P LK L GH A++++ ++PN + +A+SS D + +W GH + D
Sbjct: 33 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISD 92
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V +SS + SAS DKT++IW + K HS V F+ + I++ S D+
Sbjct: 93 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES 152
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
V++W K + + H++ V + DGS+I S S D ++W+ SG+C+ T D
Sbjct: 153 VRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD 212
Query: 189 KGHGL-HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH-NEAVTQVAIH--PSGS 244
+ + + P+G Y+ AT +KL+D ++ Y+ H NE A G
Sbjct: 213 DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK 272
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG--DDKLVFIWKT 302
+I++ S+D + I +L + L GH V + PT + +SA +DK + +WK+
Sbjct: 273 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 332
Query: 303 N 303
+
Sbjct: 333 D 333
Score = 54.8 bits (126), Expect = 1e-06
Identities = 35/133 (26%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-RG-TMRSYRFQGHDE 64
T CLK + ++ + ++PN + I ++LDN++ LWD +G +++Y +++
Sbjct: 200 TASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEK 259
Query: 65 AVMDVTFS-SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITA 123
+ FS + GK++ S S D V IW + H+ V S + I +A
Sbjct: 260 YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASA 319
Query: 124 S--DDKVVKLWST 134
+ +DK +KLW +
Sbjct: 320 ALENDKTIKLWKS 332
>AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein
protein.
Length = 362
Score = 139 bits (337), Expect = 4e-32
Identities = 85/301 (28%), Positives = 145/301 (48%), Gaps = 6/301 (1%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P LK L GH A++++ ++PN + +A+SS D + +W GH + D
Sbjct: 61 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISD 120
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V +SS + SAS DKT++IW + K HS V F+ + I++ S D+
Sbjct: 121 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES 180
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
V++W K + + H++ V + DGS+I S S D ++W+ SG+C+ T D
Sbjct: 181 VRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD 240
Query: 189 KGHGL-HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH-NEAVTQVAIH--PSGS 244
+ + + P+G Y+ AT +KL+D ++ Y+ H NE A G
Sbjct: 241 DNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGK 300
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG--DDKLVFIWKT 302
+I++ S+D + I +L + L GH V + PT + +SA +DK + +WK+
Sbjct: 301 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKS 360
Query: 303 N 303
+
Sbjct: 361 D 361
Score = 54.8 bits (126), Expect = 1e-06
Identities = 35/133 (26%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-RG-TMRSYRFQGHDE 64
T CLK + ++ + ++PN + I ++LDN++ LWD +G +++Y +++
Sbjct: 228 TASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEK 287
Query: 65 AVMDVTFS-SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITA 123
+ FS + GK++ S S D V IW + H+ V S + I +A
Sbjct: 288 YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASA 347
Query: 124 S--DDKVVKLWST 134
+ +DK +KLW +
Sbjct: 348 ALENDKTIKLWKS 360
>CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein.
Length = 330
Score = 136 bits (330), Expect = 3e-31
Identities = 85/301 (28%), Positives = 144/301 (47%), Gaps = 6/301 (1%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P LK L GH A++++ ++PN + +A+SS D +++W GH+ + D
Sbjct: 29 PNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISD 88
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V +SS + SAS DKT+++W K HS V F+ + II+ S D+
Sbjct: 89 VAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDET 148
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
VK+W K + + H++ V + GS+I S S D ++W+ SG+C+ T D
Sbjct: 149 VKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDD 208
Query: 189 KGHGL-HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH-NEAVTQVAIH--PSGS 244
+ + + P+G Y+ AT +KL+D ++ Y+ H NE A G
Sbjct: 209 DNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGK 268
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG--DDKLVFIWKT 302
+I++ S+D + I +L + L GH V + PT + +SA +DK + +W +
Sbjct: 269 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMS 328
Query: 303 N 303
N
Sbjct: 329 N 329
Score = 105 bits (251), Expect = 1e-21
Identities = 66/255 (25%), Positives = 119/255 (46%), Gaps = 4/255 (1%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
+K L GH I+ + ++ + ++ ++S D ++ LWD+R +GH V F+
Sbjct: 76 EKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNP 135
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S S D+TV+IW AHS V +V F+ GS I++ S D + ++W
Sbjct: 136 PSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWD 195
Query: 134 THKHKFISSFVGHTN-WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG-- 190
+ + + V N V + S +G I + + D + KLW+ G C+ TY K
Sbjct: 196 AASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEK 255
Query: 191 HGLHLAWHPSGCYVAVATSHGN-VKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
+ + + +G V+ S N V +++++T +VQ H + V A HP+ + I +A
Sbjct: 256 YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASA 315
Query: 250 SKDGKMKILDLLEGH 264
+ + I + H
Sbjct: 316 ALENDKTIKLWMSNH 330
>BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B
protein.
Length = 330
Score = 136 bits (330), Expect = 3e-31
Identities = 85/301 (28%), Positives = 144/301 (47%), Gaps = 6/301 (1%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P LK L GH A++++ ++PN + +A+SS D +++W GH+ + D
Sbjct: 29 PNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISD 88
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V +SS + SAS DKT+++W K HS V F+ + II+ S D+
Sbjct: 89 VAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDET 148
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
VK+W K + + H++ V + GS+I S S D ++W+ SG+C+ T D
Sbjct: 149 VKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDD 208
Query: 189 KGHGL-HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH-NEAVTQVAIH--PSGS 244
+ + + P+G Y+ AT +KL+D ++ Y+ H NE A G
Sbjct: 209 DNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGK 268
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG--DDKLVFIWKT 302
+I++ S+D + I +L + L GH V + PT + +SA +DK + +W +
Sbjct: 269 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMS 328
Query: 303 N 303
N
Sbjct: 329 N 329
Score = 105 bits (251), Expect = 1e-21
Identities = 66/255 (25%), Positives = 119/255 (46%), Gaps = 4/255 (1%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
+K L GH I+ + ++ + ++ ++S D ++ LWD+R +GH V F+
Sbjct: 76 EKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNP 135
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S S D+TV+IW AHS V +V F+ GS I++ S D + ++W
Sbjct: 136 PSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWD 195
Query: 134 THKHKFISSFVGHTN-WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG-- 190
+ + + V N V + S +G I + + D + KLW+ G C+ TY K
Sbjct: 196 AASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEK 255
Query: 191 HGLHLAWHPSGCYVAVATSHGN-VKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
+ + + +G V+ S N V +++++T +VQ H + V A HP+ + I +A
Sbjct: 256 YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASA 315
Query: 250 SKDGKMKILDLLEGH 264
+ + I + H
Sbjct: 316 ALENDKTIKLWMSNH 330
>AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ11287 fis, clone PLACE1009596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 330
Score = 134 bits (325), Expect = 1e-30
Identities = 86/301 (28%), Positives = 142/301 (47%), Gaps = 6/301 (1%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P LK L GH A++++ ++PN + +A+SS D +++W GH+ + D
Sbjct: 29 PNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISD 88
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V +SS + SAS DKT+++W K HS V F+ + II+ S D+
Sbjct: 89 VAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDET 148
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
VK+W K + + H++ V + GS+I S S D ++W+ SG+C+ T D
Sbjct: 149 VKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDD 208
Query: 189 KGHGL-HLAWHPSGCYVAVATSHGNVKLYDI-RTHNLVQYYSIHNEAVTQVAIH--PSGS 244
+ + + P+G Y+ AT +KL+D R L Y NE A G
Sbjct: 209 DNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQKNEKYCIFANFSVTGGK 268
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG--DDKLVFIWKT 302
+I++ S+D + I +L + L GH V + PT + +SA +DK + +W +
Sbjct: 269 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMS 328
Query: 303 N 303
N
Sbjct: 329 N 329
Score = 105 bits (252), Expect = 8e-22
Identities = 66/255 (25%), Positives = 119/255 (46%), Gaps = 4/255 (1%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
+K L GH I+ + ++ + ++ ++S D ++ LWD+R +GH V F+
Sbjct: 76 EKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNP 135
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S S D+TV+IW AHS V +V F+ GS I++ S D + ++W
Sbjct: 136 PSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWD 195
Query: 134 THKHKFISSFVGHTN-WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG-- 190
+ + + V N V + S +G I + + D + KLW+ G C+ TY K
Sbjct: 196 AASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQKNEK 255
Query: 191 HGLHLAWHPSGCYVAVATSHGN-VKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
+ + + +G V+ S N V +++++T +VQ H + V A HP+ + I +A
Sbjct: 256 YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASA 315
Query: 250 SKDGKMKILDLLEGH 264
+ + I + H
Sbjct: 316 ALENDKTIKLWMSNH 330
>L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 288
Score = 133 bits (321), Expect = 3e-30
Identities = 73/286 (25%), Positives = 136/286 (47%), Gaps = 20/286 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+ ++S D ++ +WD +GH ++V D++F SGK +AS S D T+++W
Sbjct: 1 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 60
Query: 96 GSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
H V SV +G I++AS DK +K+W + +F GH WVR R
Sbjct: 61 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 120
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN--- 212
+ DG++IASCS+D++ ++W + + EC ++ + ++W P Y +++ + G+
Sbjct: 121 NQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETK 180
Query: 213 -----------------VKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKM 255
+K++D+ T + H+ V V H G +IL+ + D +
Sbjct: 181 KSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTXVGHDNWVRGVLFHSGGKFILSCADDKTL 240
Query: 256 KILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
++ D + TL+ H V +++F T + D+ V +W+
Sbjct: 241 RVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 286
Score = 109 bits (261), Expect = 6e-23
Identities = 64/264 (24%), Positives = 123/264 (46%), Gaps = 20/264 (7%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ LKGH +++ + ++ + + +A+ S D ++ LWD +G GHD V V
Sbjct: 21 ERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMP 80
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW- 132
+G ++ SASRDKT+++W F H + VR V+ + DG+ I + S+D+ V++W
Sbjct: 81 NGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 140
Query: 133 ----------STHKH--KFIS-------SFVGHTNWVRCARMSNDGSIIASCSDDKSTKL 173
H+H + IS S + + G + S S DK+ K+
Sbjct: 141 VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKM 200
Query: 174 WNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
W++ +G C+ T + +H G ++ ++++D + ++ + H
Sbjct: 201 WDVSTGMCLMTXVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHF 260
Query: 234 VTQVAIHPSGSYILTASKDGKMKI 257
VT + H + Y++T S D +K+
Sbjct: 261 VTSLDFHKTAPYVVTGSVDQTVKV 284
Score = 100 bits (240), Expect = 2e-20
Identities = 56/225 (24%), Positives = 102/225 (45%), Gaps = 20/225 (8%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ + GH + ++++ PN I ++S D ++ +W+++ F GH E V V +
Sbjct: 64 RTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQD 123
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK--------------- 119
G +AS S D+TVR+WV + H V + ++ + S
Sbjct: 124 GTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSG 183
Query: 120 -----IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
+++ S DK +K+W + + VGH NWVR + G I SC+DDK+ ++W
Sbjct: 184 KPGPFLLSGSRDKTIKMWDVSTGMCLMTXVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 243
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+ + C+ T + L +H + YV + VK+++ R
Sbjct: 244 DYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 288
Score = 77.0 bits (181), Expect = 3e-13
Identities = 40/154 (25%), Positives = 82/154 (53%)
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTH 221
+ S S+D + K+W+ ++G+ T K +++ SG +A ++ +KL+D +
Sbjct: 1 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 60
Query: 222 NLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNF 281
++ H+ V+ VAI P+G +I++AS+D +K+ ++ G+ + T +GH V V
Sbjct: 61 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRP 120
Query: 282 SPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENE 315
+ G +S +D+ V +W + +E +E+E
Sbjct: 121 NQDGTLIASCSNDQTVRVWVVATKECKAELREHE 154
>M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.3
protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 222
>AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7
protein.
Length = 347
Score = 125 bits (301), Expect = 9e-28
Identities = 92/312 (29%), Positives = 139/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 32 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 91
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 92 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 151
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 152 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 211
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D+ Y++ +
Sbjct: 212 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK--HLYTLDGGDIINAL 269
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 270 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 329
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 330 AGYTDNLVRVWQ 341
Score = 59.3 bits (137), Expect = 6e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 39 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 98
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 99 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 158
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 159 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 216
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 217 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN 252
Score = 58.8 bits (136), Expect = 9e-08
Identities = 51/198 (25%), Positives = 84/198 (42%), Gaps = 11/198 (5%)
Query: 113 FSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWV-RCARMSNDGSIIASCSDDKST 171
FS S I+ A+ + T + + GH WV + A +I S S DK+
Sbjct: 11 FSKPSSAILVAAATHALAAAMTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTI 70
Query: 172 KLWNLDSGECIH--TYKDLKGHG---LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQY 226
+W L E + + L+GH + G + + G ++L+D+ T +
Sbjct: 71 IMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRR 130
Query: 227 YSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTL--SGHNGPVNAVNFSPT 284
+ H + V VA I++ S+D +K+ + L G +T+ H+ V+ V FSP
Sbjct: 131 FVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPN 189
Query: 285 GDT--FSSAGDDKLVFIW 300
S G DKLV +W
Sbjct: 190 SSNPIIVSCGWDKLVKVW 207
>AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 varia
protein.
Length = 317
Score = 124 bits (299), Expect = 2e-27
Identities = 92/312 (29%), Positives = 138/312 (44%), Gaps = 20/312 (6%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPN-DQQIATSSLDNSVLLWDLRGTMRSY-----RFQG 61
T + L+ LKGH +T + P I ++S D ++++W L +Y +G
Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRG 61
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H V DV SS G++ S S D T+R+W T +T F H++ V SV FSSD +I+
Sbjct: 62 HSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIV 121
Query: 122 TASDDKVVKLWST-HKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDS 178
+ S DK +KLW+T K+ H+ WV C R S + S II SC DK K+WNL +
Sbjct: 122 SGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ + G+ + P G A G L+D Y++ +
Sbjct: 182 CKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDFNEGK--HLYTLDGGDIINAL 239
Query: 239 IHPSGSYILTASKDGKMKILDL--------LEGHPIFTLSGHNGP-VNAVNFSPTGDTFS 289
Y L A+ +KI DL L+ I T S P ++ +S G T
Sbjct: 240 CFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLF 299
Query: 290 SAGDDKLVFIWK 301
+ D LV +W+
Sbjct: 300 AGYTDNLVRVWQ 311
Score = 58.8 bits (136), Expect = 9e-08
Identities = 52/216 (24%), Positives = 92/216 (42%), Gaps = 13/216 (6%)
Query: 99 GMFKAHSQTVRSVQFSSD-GSKIITASDDKVVKLWSTHKHKFI-----SSFVGHTNWVRC 152
G K H+ V + + I++AS DK + +W + + + GH+++V
Sbjct: 9 GTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSD 68
Query: 153 ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN 212
+S+DG S S D + +LW+L +G + L +A+ + +
Sbjct: 69 VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKT 128
Query: 213 VKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIF 267
+KL++ T + +Y H+E V+ V P+ S I++ D +K+ +L
Sbjct: 129 IKLWN--TLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKT 186
Query: 268 TLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH G +N V SP G +S G D +W N
Sbjct: 187 NHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDFN 222
>AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit
protein.
Length = 655
Score = 122 bits (294), Expect = 6e-27
Identities = 65/199 (32%), Positives = 100/199 (50%), Gaps = 1/199 (0%)
Query: 103 AHSQTVRSVQFS-SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
AH+ V S+ + G + T DD V LWS +K I S GHT+ V R++ +
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTH 221
I + S S ++W+L++ + + T LK + L +HP G +VA + N+KL+DIR
Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
Query: 222 NLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNF 281
V Y H++AV + P G ++ +A+ D +K+ DL G + GH GPVN V F
Sbjct: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
Query: 282 SPTGDTFSSAGDDKLVFIW 300
P +S D + W
Sbjct: 198 HPNEYLLASGSSDGTIRFW 216
Score = 105 bits (251), Expect = 1e-21
Identities = 52/186 (27%), Positives = 90/186 (48%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH + + ++ N ++ I S S+ +WDL G + + F G+
Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGE 118
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++AS S+D +++W G ++ HSQ VR ++FS DG + +A+DD VKLW
Sbjct: 119 FVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 178
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
K +S F GHT V + ++AS S D + + W+L+ + + + G +
Sbjct: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDGTIRFWDLEKFQVVSRIEGEPGPVRSVL 238
Query: 197 WHPSGC 202
++P GC
Sbjct: 239 FNPDGC 244
Score = 95.9 bits (228), Expect = 6e-19
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 1/230 (0%)
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+SG+ +A+ D V +W H+ V SV+ ++ I+ S +++W
Sbjct: 31 ASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + + +G + G +AS S D + KLW++ C+ Y+
Sbjct: 91 DLEAAKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAV 150
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
L + P G ++A A VKL+D+ ++ + H V V HP+ + + S D
Sbjct: 151 RCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKL-VFIWK 301
G ++ DL + + + G GPV +V F+P G S D L V+ W+
Sbjct: 211 GTIRFWDLEKFQVVSRIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWE 260
Score = 95.1 bits (226), Expect = 1e-18
Identities = 57/252 (22%), Positives = 108/252 (42%), Gaps = 1/252 (0%)
Query: 2 MEDKVTTPEPCLKKQLKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQ 60
M V T +++ H + +++L + + +AT D V LW +
Sbjct: 1 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLT 60
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKI 120
GH V V ++ + + + S+ ++R+W + S+ F G +
Sbjct: 61 GHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGEFV 120
Query: 121 ITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGE 180
+ S D +KLW + + + GH+ VRC R S DG +AS +DD + KLW+L +G+
Sbjct: 121 ASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
Query: 181 CIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIH 240
+ + G + +HP+ +A +S G ++ +D+ +V V V +
Sbjct: 181 MMSEFPGHTGPVNVVEFHPNEYLLASGSSDGTIRFWDLEKFQVVSRIEGEPGPVRSVLFN 240
Query: 241 PSGSYILTASKD 252
P G + + +D
Sbjct: 241 PDGCCLYSGCQD 252
Score = 92.7 bits (220), Expect = 6e-18
Identities = 59/203 (29%), Positives = 96/203 (47%), Gaps = 4/203 (1%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ L G K I +L ++P + +A+ S D ++ LWD+R +R++GH +AV + FS
Sbjct: 99 RTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPD 158
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
GK++ASA+ D TV++W T F H+ V V+F + + + S D ++ W
Sbjct: 159 GKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDGTIRFWDL 218
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIAS-CSDDKSTKLWNLDSGECIHTYKDLKGHGL 193
K + +S G VR + DG + S C D S +++ + C G
Sbjct: 219 EKFQVVSRIEGEPGPVRSVLFNPDGCCLYSGCQD--SLRVYGWEPERCFDVVLVNWGKVA 276
Query: 194 HLAWHPSGCYVAVATSHGNVKLY 216
LA + + VA S NV Y
Sbjct: 277 DLA-ICNDQLIGVAFSQSNVSSY 298
Score = 66.5 bits (155), Expect = 4e-10
Identities = 34/158 (21%), Positives = 70/158 (44%)
Query: 159 GSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI 218
G ++A+ DD LW+++ CI + + + + + G+++++D+
Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
Query: 219 RTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNA 278
+++ + + HP G ++ + S+D +K+ D+ +F GH+ V
Sbjct: 93 EAAKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
Query: 279 VNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEG 316
+ FSP G +SA DD V +W + SE + G
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190
>EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein.
Length = 357
Score = 122 bits (293), Expect = 8e-27
Identities = 79/293 (26%), Positives = 134/293 (45%), Gaps = 11/293 (3%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR-FQGHDEAVMDVTFSSSG 75
L GH+ + ++PN +A++ D +LLW++ G +Y +GH AVM++ +++ G
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII-TASDDKVVKLWST 134
+ SAS DKTV +W K H+ V S + G +++ T SDD VKLW
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
K I +F +T V ++ I S D K+W+L + +T +
Sbjct: 182 RKKAAIQTF-QNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTG 240
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIR----THNLVQYY--SIHN--EAVTQVAIHPSGSYI 246
L+ G Y+ V+++D+R V+ + ++HN + + + + P GS I
Sbjct: 241 LSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKI 300
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
S D + + D ++ L GH G +N V F P SA DK +++
Sbjct: 301 AAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYM 353
Score = 106 bits (255), Expect = 3e-22
Identities = 64/252 (25%), Positives = 124/252 (49%), Gaps = 11/252 (4%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
GH+ V F +G +ASA D+ + +W V + K HS V + +++DGS
Sbjct: 64 GHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSM 123
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVR-CARMSNDGSIIASCSDDKSTKLWNLDS 178
+ +AS DK V +W + + + GHT++V C ++ + SDD + KLW++
Sbjct: 124 LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRK 183
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
I T+++ L + ++ + + ++K++D+R + L H ++VT ++
Sbjct: 184 KAAIQTFQNTY-QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHP------IFTLSGHNGPVNAV--NFSPTGDTFSS 290
+ GSY+L+ + D +++ D+ P IF + HN N + ++SP G ++
Sbjct: 243 LSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAA 302
Query: 291 AGDDKLVFIWKT 302
D+ V++W T
Sbjct: 303 GSADRFVYVWDT 314
Score = 83.0 bits (196), Expect = 5e-15
Identities = 57/215 (26%), Positives = 102/215 (47%), Gaps = 12/215 (5%)
Query: 15 KQLKGHKNAITALY-YNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
K+LKGH + + + Y Q + T S D +V LWD+R FQ + V+ VTF+
Sbjct: 145 KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQ-VLAVTFND 203
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ + S D +++W T + H+ +V + SS+GS +++ + D V++W
Sbjct: 204 TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263
Query: 134 TH----KHKFISSFVGHT-----NWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
K + + F G+ N +RC+ S DGS IA+ S D+ +W+ S ++
Sbjct: 264 VRPFAPKERCVKIFQGNVHNFEKNLLRCS-WSPDGSKIAAGSADRFVYVWDTTSRRILYK 322
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
G +A+HP + A+S + + +I+
Sbjct: 323 LPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
Score = 82.2 bits (194), Expect = 8e-15
Identities = 54/206 (26%), Positives = 97/206 (47%), Gaps = 9/206 (4%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH-KFISSFVGHTNWVRCARMSND 158
+ H V +F +GS + +A D+++ LW+ + ++ GH+ V + D
Sbjct: 61 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTD 120
Query: 159 GSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPS---GCYVAVATSHGNVK 214
GS++ S S DK+ +W+ ++GE + K LKGH + + +P+ V + G VK
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERV---KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVK 177
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
L+DIR +Q + + V V + + I++ D +K+ DL + +T+ GH
Sbjct: 178 LWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD 236
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ S G S D V +W
Sbjct: 237 SVTGLSLSSEGSYLLSNAMDNTVRVW 262
Score = 44.8 bits (101), Expect = 0.001
Identities = 18/36 (50%), Positives = 22/36 (61%)
Query: 265 PIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
PI LSGH G V F P G T +SAG D+L+ +W
Sbjct: 58 PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLW 93
>BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 122 bits (293), Expect = 8e-27
Identities = 79/293 (26%), Positives = 134/293 (45%), Gaps = 11/293 (3%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR-FQGHDEAVMDVTFSSSG 75
L GH+ + ++PN +A++ D +LLW++ G +Y +GH AVM++ +++ G
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII-TASDDKVVKLWST 134
+ SAS DKTV +W K H+ V S + G +++ T SDD VKLW
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
K I +F +T V ++ I S D K+W+L + +T +
Sbjct: 182 RKKAAIQTF-QNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTG 240
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIR----THNLVQYY--SIHN--EAVTQVAIHPSGSYI 246
L+ G Y+ V+++D+R V+ + ++HN + + + + P GS I
Sbjct: 241 LSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKI 300
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
S D + + D ++ L GH G +N V F P SA DK +++
Sbjct: 301 AAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYM 353
Score = 106 bits (255), Expect = 3e-22
Identities = 64/252 (25%), Positives = 124/252 (49%), Gaps = 11/252 (4%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
GH+ V F +G +ASA D+ + +W V + K HS V + +++DGS
Sbjct: 64 GHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSM 123
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVR-CARMSNDGSIIASCSDDKSTKLWNLDS 178
+ +AS DK V +W + + + GHT++V C ++ + SDD + KLW++
Sbjct: 124 LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRK 183
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
I T+++ L + ++ + + ++K++D+R + L H ++VT ++
Sbjct: 184 KAAIQTFQNTY-QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHP------IFTLSGHNGPVNAV--NFSPTGDTFSS 290
+ GSY+L+ + D +++ D+ P IF + HN N + ++SP G ++
Sbjct: 243 LSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAA 302
Query: 291 AGDDKLVFIWKT 302
D+ V++W T
Sbjct: 303 GSADRFVYVWDT 314
Score = 83.0 bits (196), Expect = 5e-15
Identities = 57/215 (26%), Positives = 102/215 (47%), Gaps = 12/215 (5%)
Query: 15 KQLKGHKNAITALY-YNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
K+LKGH + + + Y Q + T S D +V LWD+R FQ + V+ VTF+
Sbjct: 145 KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQ-VLAVTFND 203
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ + S D +++W T + H+ +V + SS+GS +++ + D V++W
Sbjct: 204 TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263
Query: 134 TH----KHKFISSFVGHT-----NWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
K + + F G+ N +RC+ S DGS IA+ S D+ +W+ S ++
Sbjct: 264 VRPFAPKERCVKIFQGNVHNFEKNLLRCS-WSPDGSKIAAGSADRFVYVWDTTSRRILYK 322
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
G +A+HP + A+S + + +I+
Sbjct: 323 LPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
Score = 82.2 bits (194), Expect = 8e-15
Identities = 54/206 (26%), Positives = 97/206 (47%), Gaps = 9/206 (4%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH-KFISSFVGHTNWVRCARMSND 158
+ H V +F +GS + +A D+++ LW+ + ++ GH+ V + D
Sbjct: 61 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTD 120
Query: 159 GSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPS---GCYVAVATSHGNVK 214
GS++ S S DK+ +W+ ++GE + K LKGH + + +P+ V + G VK
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERV---KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVK 177
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
L+DIR +Q + + V V + + I++ D +K+ DL + +T+ GH
Sbjct: 178 LWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD 236
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ S G S D V +W
Sbjct: 237 SVTGLSLSSEGSYLLSNAMDNTVRVW 262
Score = 44.8 bits (101), Expect = 0.001
Identities = 18/36 (50%), Positives = 22/36 (61%)
Query: 265 PIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
PI LSGH G V F P G T +SAG D+L+ +W
Sbjct: 58 PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLW 93
>AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 122 bits (293), Expect = 8e-27
Identities = 79/293 (26%), Positives = 134/293 (45%), Gaps = 11/293 (3%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR-FQGHDEAVMDVTFSSSG 75
L GH+ + ++PN +A++ D +LLW++ G +Y +GH AVM++ +++ G
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII-TASDDKVVKLWST 134
+ SAS DKTV +W K H+ V S + G +++ T SDD VKLW
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
K I +F +T V ++ I S D K+W+L + +T +
Sbjct: 182 RKKAAIQTF-QNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTG 240
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIR----THNLVQYY--SIHN--EAVTQVAIHPSGSYI 246
L+ G Y+ V+++D+R V+ + ++HN + + + + P GS I
Sbjct: 241 LSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKI 300
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
S D + + D ++ L GH G +N V F P SA DK +++
Sbjct: 301 AAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYM 353
Score = 106 bits (255), Expect = 3e-22
Identities = 64/252 (25%), Positives = 124/252 (49%), Gaps = 11/252 (4%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
GH+ V F +G +ASA D+ + +W V + K HS V + +++DGS
Sbjct: 64 GHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSM 123
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVR-CARMSNDGSIIASCSDDKSTKLWNLDS 178
+ +AS DK V +W + + + GHT++V C ++ + SDD + KLW++
Sbjct: 124 LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRK 183
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
I T+++ L + ++ + + ++K++D+R + L H ++VT ++
Sbjct: 184 KAAIQTFQNTY-QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHP------IFTLSGHNGPVNAV--NFSPTGDTFSS 290
+ GSY+L+ + D +++ D+ P IF + HN N + ++SP G ++
Sbjct: 243 LSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAA 302
Query: 291 AGDDKLVFIWKT 302
D+ V++W T
Sbjct: 303 GSADRFVYVWDT 314
Score = 83.0 bits (196), Expect = 5e-15
Identities = 57/215 (26%), Positives = 102/215 (47%), Gaps = 12/215 (5%)
Query: 15 KQLKGHKNAITALY-YNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
K+LKGH + + + Y Q + T S D +V LWD+R FQ + V+ VTF+
Sbjct: 145 KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQ-VLAVTFND 203
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ + S D +++W T + H+ +V + SS+GS +++ + D V++W
Sbjct: 204 TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263
Query: 134 TH----KHKFISSFVGHT-----NWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
K + + F G+ N +RC+ S DGS IA+ S D+ +W+ S ++
Sbjct: 264 VRPFAPKERCVKIFQGNVHNFEKNLLRCS-WSPDGSKIAAGSADRFVYVWDTTSRRILYK 322
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
G +A+HP + A+S + + +I+
Sbjct: 323 LPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
Score = 82.2 bits (194), Expect = 8e-15
Identities = 54/206 (26%), Positives = 97/206 (47%), Gaps = 9/206 (4%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH-KFISSFVGHTNWVRCARMSND 158
+ H V +F +GS + +A D+++ LW+ + ++ GH+ V + D
Sbjct: 61 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTD 120
Query: 159 GSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPS---GCYVAVATSHGNVK 214
GS++ S S DK+ +W+ ++GE + K LKGH + + +P+ V + G VK
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERV---KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVK 177
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
L+DIR +Q + + V V + + I++ D +K+ DL + +T+ GH
Sbjct: 178 LWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD 236
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ S G S D V +W
Sbjct: 237 SVTGLSLSSEGSYLLSNAMDNTVRVW 262
Score = 44.8 bits (101), Expect = 0.001
Identities = 18/36 (50%), Positives = 22/36 (61%)
Query: 265 PIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
PI LSGH G V F P G T +SAG D+L+ +W
Sbjct: 58 PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLW 93
>CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein.
Length = 655
Score = 121 bits (291), Expect = 1e-26
Identities = 64/199 (32%), Positives = 100/199 (50%), Gaps = 1/199 (0%)
Query: 103 AHSQTVRSVQFS-SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
AH+ V S+ + G + T DD V LWS +K I S GHT+ V R++ +
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTH 221
I + S S ++W+L++ + + T K + L +HP G +VA + N+KL+DIR
Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
Query: 222 NLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNF 281
V Y H++AV + P G ++ +A+ D +K+ DL G + GH GPVN V F
Sbjct: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
Query: 282 SPTGDTFSSAGDDKLVFIW 300
P +S D+ + W
Sbjct: 198 HPNEYLLASGSSDRTIRFW 216
Score = 111 bits (266), Expect = 2e-23
Identities = 53/186 (28%), Positives = 92/186 (49%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH + + ++ N ++ I S S+ +WDL GH + + F G+
Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGE 118
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++AS S+D +++W G ++ HSQ VR ++FS DG + +A+DD VKLW
Sbjct: 119 FVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 178
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
K +S F GHT V + ++AS S D++ + W+L+ + + + G +
Sbjct: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
Query: 197 WHPSGC 202
++P GC
Sbjct: 239 FNPDGC 244
Score = 98.7 bits (235), Expect = 9e-20
Identities = 60/203 (29%), Positives = 98/203 (48%), Gaps = 4/203 (1%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ L GHK I +L ++P + +A+ S D ++ LWD+R +R++GH +AV + FS
Sbjct: 99 RTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPD 158
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
GK++ASA+ D TV++W T F H+ V V+F + + + S D+ ++ W
Sbjct: 159 GKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIAS-CSDDKSTKLWNLDSGECIHTYKDLKGHGL 193
K + +S G VR + DG + S C D S +++ + C G
Sbjct: 219 EKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD--SLRVYGWEPERCFDVVLVNWGKVA 276
Query: 194 HLAWHPSGCYVAVATSHGNVKLY 216
LA + + VA S NV Y
Sbjct: 277 DLA-ICNDQLIGVAFSQSNVSSY 298
Score = 97.1 bits (231), Expect = 3e-19
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 1/230 (0%)
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+SG+ +A+ D V +W H+ V SV+ ++ I+ S +++W
Sbjct: 31 ASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + + +GH + G +AS S D + KLW++ C+ Y+
Sbjct: 91 DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAV 150
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
L + P G ++A A VKL+D+ ++ + H V V HP+ + + S D
Sbjct: 151 RCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKL-VFIWK 301
++ DL + + + G GPV +V F+P G S D L V+ W+
Sbjct: 211 RTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWE 260
Score = 96.3 bits (229), Expect = 5e-19
Identities = 57/252 (22%), Positives = 108/252 (42%), Gaps = 1/252 (0%)
Query: 2 MEDKVTTPEPCLKKQLKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQ 60
M V T +++ H + +++L + + +AT D V LW +
Sbjct: 1 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLT 60
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKI 120
GH V V ++ + + + S+ ++R+W H + S+ F G +
Sbjct: 61 GHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFV 120
Query: 121 ITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGE 180
+ S D +KLW + + + GH+ VRC R S DG +AS +DD + KLW+L +G+
Sbjct: 121 ASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
Query: 181 CIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIH 240
+ + G + +HP+ +A +S ++ +D+ +V V V +
Sbjct: 181 MMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFN 240
Query: 241 PSGSYILTASKD 252
P G + + +D
Sbjct: 241 PDGCCLYSGCQD 252
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/158 (22%), Positives = 71/158 (44%)
Query: 159 GSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI 218
G ++A+ DD LW+++ CI + + + + + G+++++D+
Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
Query: 219 RTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNA 278
+++ H + + HP G ++ + S+D +K+ D+ +F GH+ V
Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
Query: 279 VNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEG 316
+ FSP G +SA DD V +W + SE + G
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190
>BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80
(WD40-containing) subunit B 1 protein.
Length = 655
Score = 121 bits (291), Expect = 1e-26
Identities = 64/199 (32%), Positives = 100/199 (50%), Gaps = 1/199 (0%)
Query: 103 AHSQTVRSVQFS-SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
AH+ V S+ + G + T DD V LWS +K I S GHT+ V R++ +
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTH 221
I + S S ++W+L++ + + T K + L +HP G +VA + N+KL+DIR
Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
Query: 222 NLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNF 281
V Y H++AV + P G ++ +A+ D +K+ DL G + GH GPVN V F
Sbjct: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
Query: 282 SPTGDTFSSAGDDKLVFIW 300
P +S D+ + W
Sbjct: 198 HPNEYLLASGSSDRTIRFW 216
Score = 111 bits (266), Expect = 2e-23
Identities = 53/186 (28%), Positives = 92/186 (49%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH + + ++ N ++ I S S+ +WDL GH + + F G+
Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGE 118
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++AS S+D +++W G ++ HSQ VR ++FS DG + +A+DD VKLW
Sbjct: 119 FVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 178
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
K +S F GHT V + ++AS S D++ + W+L+ + + + G +
Sbjct: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
Query: 197 WHPSGC 202
++P GC
Sbjct: 239 FNPDGC 244
Score = 98.7 bits (235), Expect = 9e-20
Identities = 60/203 (29%), Positives = 98/203 (48%), Gaps = 4/203 (1%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ L GHK I +L ++P + +A+ S D ++ LWD+R +R++GH +AV + FS
Sbjct: 99 RTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPD 158
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
GK++ASA+ D TV++W T F H+ V V+F + + + S D+ ++ W
Sbjct: 159 GKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIAS-CSDDKSTKLWNLDSGECIHTYKDLKGHGL 193
K + +S G VR + DG + S C D S +++ + C G
Sbjct: 219 EKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD--SLRVYGWEPERCFDVVLVNWGKVA 276
Query: 194 HLAWHPSGCYVAVATSHGNVKLY 216
LA + + VA S NV Y
Sbjct: 277 DLA-ICNDQLIGVAFSQSNVSSY 298
Score = 97.1 bits (231), Expect = 3e-19
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 1/230 (0%)
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+SG+ +A+ D V +W H+ V SV+ ++ I+ S +++W
Sbjct: 31 ASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + + +GH + G +AS S D + KLW++ C+ Y+
Sbjct: 91 DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAV 150
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
L + P G ++A A VKL+D+ ++ + H V V HP+ + + S D
Sbjct: 151 RCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKL-VFIWK 301
++ DL + + + G GPV +V F+P G S D L V+ W+
Sbjct: 211 RTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWE 260
Score = 96.3 bits (229), Expect = 5e-19
Identities = 57/252 (22%), Positives = 108/252 (42%), Gaps = 1/252 (0%)
Query: 2 MEDKVTTPEPCLKKQLKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQ 60
M V T +++ H + +++L + + +AT D V LW +
Sbjct: 1 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLT 60
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKI 120
GH V V ++ + + + S+ ++R+W H + S+ F G +
Sbjct: 61 GHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFV 120
Query: 121 ITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGE 180
+ S D +KLW + + + GH+ VRC R S DG +AS +DD + KLW+L +G+
Sbjct: 121 ASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
Query: 181 CIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIH 240
+ + G + +HP+ +A +S ++ +D+ +V V V +
Sbjct: 181 MMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFN 240
Query: 241 PSGSYILTASKD 252
P G + + +D
Sbjct: 241 PDGCCLYSGCQD 252
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/158 (22%), Positives = 71/158 (44%)
Query: 159 GSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI 218
G ++A+ DD LW+++ CI + + + + + G+++++D+
Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
Query: 219 RTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNA 278
+++ H + + HP G ++ + S+D +K+ D+ +F GH+ V
Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
Query: 279 VNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEG 316
+ FSP G +SA DD V +W + SE + G
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190
>BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat
containing) subunit B 1 protein.
Length = 655
Score = 121 bits (291), Expect = 1e-26
Identities = 64/199 (32%), Positives = 100/199 (50%), Gaps = 1/199 (0%)
Query: 103 AHSQTVRSVQFS-SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
AH+ V S+ + G + T DD V LWS +K I S GHT+ V R++ +
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTH 221
I + S S ++W+L++ + + T K + L +HP G +VA + N+KL+DIR
Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
Query: 222 NLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNF 281
V Y H++AV + P G ++ +A+ D +K+ DL G + GH GPVN V F
Sbjct: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
Query: 282 SPTGDTFSSAGDDKLVFIW 300
P +S D+ + W
Sbjct: 198 HPNEYLLASGSSDRTIRFW 216
Score = 111 bits (266), Expect = 2e-23
Identities = 53/186 (28%), Positives = 92/186 (49%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH + + ++ N ++ I S S+ +WDL GH + + F G+
Sbjct: 59 LTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGE 118
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++AS S+D +++W G ++ HSQ VR ++FS DG + +A+DD VKLW
Sbjct: 119 FVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA 178
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
K +S F GHT V + ++AS S D++ + W+L+ + + + G +
Sbjct: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
Query: 197 WHPSGC 202
++P GC
Sbjct: 239 FNPDGC 244
Score = 98.7 bits (235), Expect = 9e-20
Identities = 60/203 (29%), Positives = 98/203 (48%), Gaps = 4/203 (1%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
+ L GHK I +L ++P + +A+ S D ++ LWD+R +R++GH +AV + FS
Sbjct: 99 RTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPD 158
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
GK++ASA+ D TV++W T F H+ V V+F + + + S D+ ++ W
Sbjct: 159 GKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL 218
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIAS-CSDDKSTKLWNLDSGECIHTYKDLKGHGL 193
K + +S G VR + DG + S C D S +++ + C G
Sbjct: 219 EKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD--SLRVYGWEPERCFDVVLVNWGKVA 276
Query: 194 HLAWHPSGCYVAVATSHGNVKLY 216
LA + + VA S NV Y
Sbjct: 277 DLA-ICNDQLIGVAFSQSNVSSY 298
Score = 97.1 bits (231), Expect = 3e-19
Identities = 57/230 (24%), Positives = 100/230 (43%), Gaps = 1/230 (0%)
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+SG+ +A+ D V +W H+ V SV+ ++ I+ S +++W
Sbjct: 31 ASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVW 90
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + + +GH + G +AS S D + KLW++ C+ Y+
Sbjct: 91 DLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAV 150
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
L + P G ++A A VKL+D+ ++ + H V V HP+ + + S D
Sbjct: 151 RCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSD 210
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKL-VFIWK 301
++ DL + + + G GPV +V F+P G S D L V+ W+
Sbjct: 211 RTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWE 260
Score = 96.3 bits (229), Expect = 5e-19
Identities = 57/252 (22%), Positives = 108/252 (42%), Gaps = 1/252 (0%)
Query: 2 MEDKVTTPEPCLKKQLKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQ 60
M V T +++ H + +++L + + +AT D V LW +
Sbjct: 1 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLT 60
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKI 120
GH V V ++ + + + S+ ++R+W H + S+ F G +
Sbjct: 61 GHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFV 120
Query: 121 ITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGE 180
+ S D +KLW + + + GH+ VRC R S DG +AS +DD + KLW+L +G+
Sbjct: 121 ASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGK 180
Query: 181 CIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIH 240
+ + G + +HP+ +A +S ++ +D+ +V V V +
Sbjct: 181 MMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFN 240
Query: 241 PSGSYILTASKD 252
P G + + +D
Sbjct: 241 PDGCCLYSGCQD 252
Score = 70.9 bits (166), Expect = 2e-11
Identities = 35/158 (22%), Positives = 71/158 (44%)
Query: 159 GSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI 218
G ++A+ DD LW+++ CI + + + + + G+++++D+
Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92
Query: 219 RTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNA 278
+++ H + + HP G ++ + S+D +K+ D+ +F GH+ V
Sbjct: 93 EAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
Query: 279 VNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEG 316
+ FSP G +SA DD V +W + SE + G
Sbjct: 153 LRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTG 190
>AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kDa
protein protein.
Length = 357
Score = 120 bits (288), Expect = 3e-26
Identities = 78/293 (26%), Positives = 133/293 (45%), Gaps = 11/293 (3%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR-FQGHDEAVMDVTFSSSG 75
L GH+ + ++PN +A++ D +LLW++ G +Y +GH AVM++ +++ G
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII-TASDDKVVKLWST 134
+ SAS DKTV +W K H+ V S + +++ T SDD VKLW
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDI 181
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
K I +F +T V ++ I S D K+W+L + +T +
Sbjct: 182 RKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTG 240
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRT----HNLVQYY--SIHN--EAVTQVAIHPSGSYI 246
L+ G Y+ V+++D+R V+ + ++HN + + + + P GS I
Sbjct: 241 LSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKI 300
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
S D + + D ++ L GH G +N V F P SA DK +++
Sbjct: 301 AAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYM 353
Score = 107 bits (256), Expect = 2e-22
Identities = 64/252 (25%), Positives = 124/252 (49%), Gaps = 11/252 (4%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
GH+ V F +G +ASA D+ + +W V + K HS V + +++DGS
Sbjct: 64 GHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSM 123
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVR-CARMSNDGSIIASCSDDKSTKLWNLDS 178
+ +AS DK V +W + + + GHT++V C ++ + SDD + KLW++
Sbjct: 124 LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDIRK 183
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
I T+++ L + ++ + + ++K++D+R + L H ++VT ++
Sbjct: 184 KAAIQTFQNTY-QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHP------IFTLSGHNGPVNAV--NFSPTGDTFSS 290
+ GSY+L+ + D +++ D+ P IF + HN N + ++SP G ++
Sbjct: 243 LSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAA 302
Query: 291 AGDDKLVFIWKT 302
D+ V++W T
Sbjct: 303 GSADRFVYVWDT 314
Score = 83.8 bits (198), Expect = 3e-15
Identities = 57/215 (26%), Positives = 103/215 (47%), Gaps = 12/215 (5%)
Query: 15 KQLKGHKNAITALY-YNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
K+LKGH + + + Y + Q + T S D +V LWD+R FQ + V+ VTF+
Sbjct: 145 KRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQ-VLAVTFND 203
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ + S D +++W T + H+ +V + SS+GS +++ + D V++W
Sbjct: 204 TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263
Query: 134 TH----KHKFISSFVGHT-----NWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
K + + F G+ N +RC+ S DGS IA+ S D+ +W+ S ++
Sbjct: 264 VRPFAPKERCVKIFQGNVHNFEKNLLRCS-WSPDGSKIAAGSADRFVYVWDTTSRRILYK 322
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
G +A+HP + A+S + + +I+
Sbjct: 323 LPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
Score = 83.4 bits (197), Expect = 3e-15
Identities = 55/206 (26%), Positives = 97/206 (47%), Gaps = 9/206 (4%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH-KFISSFVGHTNWVRCARMSND 158
+ H V +F +GS + +A D+++ LW+ + ++ GH+ V + D
Sbjct: 61 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTD 120
Query: 159 GSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHP---SGCYVAVATSHGNVK 214
GS++ S S DK+ +W+ ++GE + K LKGH + + +P S V + G VK
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERV---KRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVK 177
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
L+DIR +Q + + V V + + I++ D +K+ DL + +T+ GH
Sbjct: 178 LWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD 236
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ S G S D V +W
Sbjct: 237 SVTGLSLSSEGSYLLSNAMDNTVRVW 262
Score = 44.8 bits (101), Expect = 0.001
Identities = 18/36 (50%), Positives = 22/36 (61%)
Query: 265 PIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
PI LSGH G V F P G T +SAG D+L+ +W
Sbjct: 58 PIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLW 93
>AL512666-1|CAH73999.1| 129|Homo sapiens tudor domain containing 3
protein.
Length = 129
Score = 117 bits (282), Expect = 2e-25
Identities = 51/98 (52%), Positives = 72/98 (73%), Gaps = 1/98 (1%)
Query: 403 MLKLTLHDGKVTCTGLEISHIPSLSINTPPGTKLLLKNEELEVCHGVVWLTPSVISVLGG 462
ML+L + DG ++CT +E S++ +S+NTPPGTK+ L +++ +G + L S +VLGG
Sbjct: 1 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGI-VDIKNGFLLLNDSNTTVLGG 59
Query: 463 TVSHMIEKWELNRSLAKHTRGGIGAEGGPPPWIPFGQR 500
V H+IEKWEL RSL+KH R IG EGGPPP++PFGQ+
Sbjct: 60 EVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQK 97
>AL354764-1|CAH72280.1| 129|Homo sapiens tudor domain containing 3
protein.
Length = 129
Score = 117 bits (282), Expect = 2e-25
Identities = 51/98 (52%), Positives = 72/98 (73%), Gaps = 1/98 (1%)
Query: 403 MLKLTLHDGKVTCTGLEISHIPSLSINTPPGTKLLLKNEELEVCHGVVWLTPSVISVLGG 462
ML+L + DG ++CT +E S++ +S+NTPPGTK+ L +++ +G + L S +VLGG
Sbjct: 1 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGI-VDIKNGFLLLNDSNTTVLGG 59
Query: 463 TVSHMIEKWELNRSLAKHTRGGIGAEGGPPPWIPFGQR 500
V H+IEKWEL RSL+KH R IG EGGPPP++PFGQ+
Sbjct: 60 EVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQK 97
>BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide binding
protein (G protein), beta 5 protein.
Length = 353
Score = 115 bits (277), Expect = 7e-25
Identities = 74/297 (24%), Positives = 130/297 (43%), Gaps = 10/297 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ LKGH N + + + + ++I +SS D V++WD T + + VM ++
Sbjct: 56 RRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAP 115
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGM------FKAHSQTVRSVQFSSDGSKIITASDDK 127
SG +A D ++ T + M H+ + + F++ +I+TAS D
Sbjct: 116 SGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDG 175
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARM--SNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
LW + + SF GH V C + S G+ S DK +W++ SG+C+ +
Sbjct: 176 TCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAF 235
Query: 186 KDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHN--EAVTQVAIHPSG 243
+ + + ++PSG A + +LYD+R V YS + + V SG
Sbjct: 236 ETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSG 295
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D + + D+L+G + L GH V+ + SP G F S D + +W
Sbjct: 296 RLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 49.2 bits (112), Expect = 7e-05
Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGT--MRSYRFQGHDEAVMDVTFSSSGKY 77
H++ I ++ Y P+ A+ S D + L+DLR + Y + V FS SG+
Sbjct: 238 HESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRL 297
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ + D T+ +W + H V +++ S DG+ + S D +++W+
Sbjct: 298 LFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 353
>AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide binding
protein beta 5 protein.
Length = 353
Score = 115 bits (277), Expect = 7e-25
Identities = 74/297 (24%), Positives = 130/297 (43%), Gaps = 10/297 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ LKGH N + + + + ++I +SS D V++WD T + + VM ++
Sbjct: 56 RRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAP 115
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGM------FKAHSQTVRSVQFSSDGSKIITASDDK 127
SG +A D ++ T + M H+ + + F++ +I+TAS D
Sbjct: 116 SGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDG 175
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARM--SNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
LW + + SF GH V C + S G+ S DK +W++ SG+C+ +
Sbjct: 176 TCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAF 235
Query: 186 KDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHN--EAVTQVAIHPSG 243
+ + + ++PSG A + +LYD+R V YS + + V SG
Sbjct: 236 ETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSG 295
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D + + D+L+G + L GH V+ + SP G F S D + +W
Sbjct: 296 RLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 49.2 bits (112), Expect = 7e-05
Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGT--MRSYRFQGHDEAVMDVTFSSSGKY 77
H++ I ++ Y P+ A+ S D + L+DLR + Y + V FS SG+
Sbjct: 238 HESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRL 297
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ + D T+ +W + H V +++ S DG+ + S D +++W+
Sbjct: 298 LFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 353
>AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide binding
protein beta subunit 5L protein.
Length = 395
Score = 115 bits (277), Expect = 7e-25
Identities = 74/297 (24%), Positives = 130/297 (43%), Gaps = 10/297 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ LKGH N + + + + ++I +SS D V++WD T + + VM ++
Sbjct: 98 RRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAP 157
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGM------FKAHSQTVRSVQFSSDGSKIITASDDK 127
SG +A D ++ T + M H+ + + F++ +I+TAS D
Sbjct: 158 SGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDG 217
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARM--SNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
LW + + SF GH V C + S G+ S DK +W++ SG+C+ +
Sbjct: 218 TCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAF 277
Query: 186 KDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHN--EAVTQVAIHPSG 243
+ + + ++PSG A + +LYD+R V YS + + V SG
Sbjct: 278 ETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSG 337
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D + + D+L+G + L GH V+ + SP G F S D + +W
Sbjct: 338 RLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
Score = 49.2 bits (112), Expect = 7e-05
Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGT--MRSYRFQGHDEAVMDVTFSSSGKY 77
H++ I ++ Y P+ A+ S D + L+DLR + Y + V FS SG+
Sbjct: 280 HESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRL 339
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ + D T+ +W + H V +++ S DG+ + S D +++W+
Sbjct: 340 LFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 395
>AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subunit
protein.
Length = 353
Score = 115 bits (277), Expect = 7e-25
Identities = 74/297 (24%), Positives = 130/297 (43%), Gaps = 10/297 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ LKGH N + + + + ++I +SS D V++WD T + + VM ++
Sbjct: 56 RRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAP 115
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGM------FKAHSQTVRSVQFSSDGSKIITASDDK 127
SG +A D ++ T + M H+ + + F++ +I+TAS D
Sbjct: 116 SGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDG 175
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARM--SNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
LW + + SF GH V C + S G+ S DK +W++ SG+C+ +
Sbjct: 176 TCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAF 235
Query: 186 KDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHN--EAVTQVAIHPSG 243
+ + + ++PSG A + +LYD+R V YS + + V SG
Sbjct: 236 ETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSG 295
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D + + D+L+G + L GH V+ + SP G F S D + +W
Sbjct: 296 RLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 49.2 bits (112), Expect = 7e-05
Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGT--MRSYRFQGHDEAVMDVTFSSSGKY 77
H++ I ++ Y P+ A+ S D + L+DLR + Y + V FS SG+
Sbjct: 238 HESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRL 297
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ + D T+ +W + H V +++ S DG+ + S D +++W+
Sbjct: 298 LFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 353
>AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymerase
II, p300/CBP-associated factor (PCAF)-associated facto
protein.
Length = 589
Score = 113 bits (271), Expect = 4e-24
Identities = 65/208 (31%), Positives = 101/208 (48%), Gaps = 6/208 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K L+GH + + + + + + S D S+ WDL + +QGH V D+ S
Sbjct: 336 KILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPY 395
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
Y AS S D+T R+W T ++ H V V+F + + + T S DK V+LWS
Sbjct: 396 SLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSA 455
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG-- 192
+ + F GH V S +G +AS +D+ KLW+L SG YK+L+GH
Sbjct: 456 QQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGT---LYKELRGHTDN 512
Query: 193 -LHLAWHPSGCYVAVATSHGNVKLYDIR 219
L + P +A A+ +V+++DIR
Sbjct: 513 ITSLTFSPDSGLIASASMDNSVRVWDIR 540
Score = 97.9 bits (233), Expect = 2e-19
Identities = 56/226 (24%), Positives = 104/226 (46%), Gaps = 2/226 (0%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDG 159
+ + H V S +F +D S +++ S+D ++ W + GH V +S
Sbjct: 337 ILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYS 396
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
AS S D++ +LW+ D + Y + +HP+ Y+A ++ V+L+ +
Sbjct: 397 LYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQ 456
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
N V+ ++ H V +A P+G Y+ +A +D ++K+ DL G L GH + ++
Sbjct: 457 QGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSL 516
Query: 280 NFSPTGDTFSSAGDDKLVFIW--KTNFTDLSSESKENEGQNMITGQ 323
FSP +SA D V +W + + ++ +E + TGQ
Sbjct: 517 TFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQ 562
Score = 96.3 bits (229), Expect = 5e-19
Identities = 50/201 (24%), Positives = 94/201 (46%)
Query: 60 QGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
+GH V F + + S S D ++R W +T +++ H+ V + S
Sbjct: 339 RGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLY 398
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG 179
+ S D+ +LWS + + + GH V C + + + +A+ S DK+ +LW+ G
Sbjct: 399 FASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQG 458
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI 239
+ + +G L LA+ P+G Y+A A +KL+D+ + L + H + +T +
Sbjct: 459 NSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTF 518
Query: 240 HPSGSYILTASKDGKMKILDL 260
P I +AS D +++ D+
Sbjct: 519 SPDSGLIASASMDNSVRVWDI 539
Score = 91.5 bits (217), Expect = 1e-17
Identities = 50/164 (30%), Positives = 76/164 (46%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + L +P A+ S D + LW T + GH V V F + Y
Sbjct: 381 QGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNY 440
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+A+ S DKTVR+W S +F H V S+ FS +G + +A +D+ +KLW
Sbjct: 441 LATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASG 500
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
GHT+ + S D +IAS S D S ++W++ + C
Sbjct: 501 TLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYC 544
Score = 50.0 bits (114), Expect = 4e-05
Identities = 23/57 (40%), Positives = 37/57 (64%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
L K+L+GH + IT+L ++P+ IA++S+DNSV +WD+R T S G ++ V
Sbjct: 502 LYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGV 558
>AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription
factor protein.
Length = 260
Score = 113 bits (271), Expect = 4e-24
Identities = 65/208 (31%), Positives = 101/208 (48%), Gaps = 6/208 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K L+GH + + + + + + S D S+ WDL + +QGH V D+ S
Sbjct: 7 KILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPY 66
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
Y AS S D+T R+W T ++ H V V+F + + + T S DK V+LWS
Sbjct: 67 SLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSA 126
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG-- 192
+ + F GH V S +G +AS +D+ KLW+L SG YK+L+GH
Sbjct: 127 QQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGT---LYKELRGHTDN 183
Query: 193 -LHLAWHPSGCYVAVATSHGNVKLYDIR 219
L + P +A A+ +V+++DIR
Sbjct: 184 ITSLTFSPDSGLIASASMDNSVRVWDIR 211
Score = 97.9 bits (233), Expect = 2e-19
Identities = 56/226 (24%), Positives = 104/226 (46%), Gaps = 2/226 (0%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDG 159
+ + H V S +F +D S +++ S+D ++ W + GH V +S
Sbjct: 8 ILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYS 67
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
AS S D++ +LW+ D + Y + +HP+ Y+A ++ V+L+ +
Sbjct: 68 LYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQ 127
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
N V+ ++ H V +A P+G Y+ +A +D ++K+ DL G L GH + ++
Sbjct: 128 QGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSL 187
Query: 280 NFSPTGDTFSSAGDDKLVFIW--KTNFTDLSSESKENEGQNMITGQ 323
FSP +SA D V +W + + ++ +E + TGQ
Sbjct: 188 TFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQ 233
Score = 96.3 bits (229), Expect = 5e-19
Identities = 50/201 (24%), Positives = 94/201 (46%)
Query: 60 QGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
+GH V F + + S S D ++R W +T +++ H+ V + S
Sbjct: 10 RGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLY 69
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG 179
+ S D+ +LWS + + + GH V C + + + +A+ S DK+ +LW+ G
Sbjct: 70 FASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQG 129
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI 239
+ + +G L LA+ P+G Y+A A +KL+D+ + L + H + +T +
Sbjct: 130 NSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTF 189
Query: 240 HPSGSYILTASKDGKMKILDL 260
P I +AS D +++ D+
Sbjct: 190 SPDSGLIASASMDNSVRVWDI 210
Score = 91.5 bits (217), Expect = 1e-17
Identities = 50/164 (30%), Positives = 76/164 (46%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + L +P A+ S D + LW T + GH V V F + Y
Sbjct: 52 QGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNY 111
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+A+ S DKTVR+W S +F H V S+ FS +G + +A +D+ +KLW
Sbjct: 112 LATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASG 171
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
GHT+ + S D +IAS S D S ++W++ + C
Sbjct: 172 TLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYC 215
Score = 50.0 bits (114), Expect = 4e-05
Identities = 23/57 (40%), Positives = 37/57 (64%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
L K+L+GH + IT+L ++P+ IA++S+DNSV +WD+R T S G ++ V
Sbjct: 173 LYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGV 229
>AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor 65
beta protein.
Length = 589
Score = 113 bits (271), Expect = 4e-24
Identities = 65/208 (31%), Positives = 101/208 (48%), Gaps = 6/208 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K L+GH + + + + + + S D S+ WDL + +QGH V D+ S
Sbjct: 336 KILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPY 395
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
Y AS S D+T R+W T ++ H V V+F + + + T S DK V+LWS
Sbjct: 396 SLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSA 455
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG-- 192
+ + F GH V S +G +AS +D+ KLW+L SG YK+L+GH
Sbjct: 456 QQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGT---LYKELRGHTDN 512
Query: 193 -LHLAWHPSGCYVAVATSHGNVKLYDIR 219
L + P +A A+ +V+++DIR
Sbjct: 513 ITSLTFSPDSGLIASASMDNSVRVWDIR 540
Score = 97.9 bits (233), Expect = 2e-19
Identities = 56/226 (24%), Positives = 104/226 (46%), Gaps = 2/226 (0%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDG 159
+ + H V S +F +D S +++ S+D ++ W + GH V +S
Sbjct: 337 ILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYS 396
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
AS S D++ +LW+ D + Y + +HP+ Y+A ++ V+L+ +
Sbjct: 397 LYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQ 456
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
N V+ ++ H V +A P+G Y+ +A +D ++K+ DL G L GH + ++
Sbjct: 457 QGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSL 516
Query: 280 NFSPTGDTFSSAGDDKLVFIW--KTNFTDLSSESKENEGQNMITGQ 323
FSP +SA D V +W + + ++ +E + TGQ
Sbjct: 517 TFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQ 562
Score = 96.3 bits (229), Expect = 5e-19
Identities = 50/201 (24%), Positives = 94/201 (46%)
Query: 60 QGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
+GH V F + + S S D ++R W +T +++ H+ V + S
Sbjct: 339 RGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLY 398
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG 179
+ S D+ +LWS + + + GH V C + + + +A+ S DK+ +LW+ G
Sbjct: 399 FASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQG 458
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI 239
+ + +G L LA+ P+G Y+A A +KL+D+ + L + H + +T +
Sbjct: 459 NSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTF 518
Query: 240 HPSGSYILTASKDGKMKILDL 260
P I +AS D +++ D+
Sbjct: 519 SPDSGLIASASMDNSVRVWDI 539
Score = 91.5 bits (217), Expect = 1e-17
Identities = 50/164 (30%), Positives = 76/164 (46%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + L +P A+ S D + LW T + GH V V F + Y
Sbjct: 381 QGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNY 440
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+A+ S DKTVR+W S +F H V S+ FS +G + +A +D+ +KLW
Sbjct: 441 LATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASG 500
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
GHT+ + S D +IAS S D S ++W++ + C
Sbjct: 501 TLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYC 544
Score = 50.0 bits (114), Expect = 4e-05
Identities = 23/57 (40%), Positives = 37/57 (64%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
L K+L+GH + IT+L ++P+ IA++S+DNSV +WD+R T S G ++ V
Sbjct: 502 LYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGV 558
>X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein.
Length = 799
Score = 112 bits (269), Expect = 7e-24
Identities = 67/226 (29%), Positives = 110/226 (48%), Gaps = 9/226 (3%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
GH V +FS Y+ S+S D TVR+W + T T G +K H+ V QFS G
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG-YKGHNYPVWDTQFSPYGYY 599
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG 179
++ D+V +LW+T ++ + F GH V C R + + +A+ S D++ +LW++ +G
Sbjct: 600 FVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNG 659
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI 239
C+ + KG L + P+G ++A + G V L+DI +V H + V +
Sbjct: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 240 HPSGSYILTASKDGKMKILDL------LEGHPIFTLSGH-NGPVNA 278
G + + S D +++ D LE T +GH N P N+
Sbjct: 720 SRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENS 765
Score = 97.9 bits (233), Expect = 2e-19
Identities = 70/290 (24%), Positives = 126/290 (43%), Gaps = 15/290 (5%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGT-MRSYRFQGHDEAVMDVTFSSSGKYMASAS 82
+TA+ + IA D++V +W + +RS + Q D +++D S
Sbjct: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVK-QASDLSLID-----------KES 520
Query: 83 RDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
D RI + HS V FS D + ++++S+D V+LWS +
Sbjct: 521 DDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 580
Query: 143 FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGC 202
+ GH V + S G S D+ +LW D + + + +HP+
Sbjct: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSN 640
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
YVA ++ V+L+D+ N V+ ++ H + + P+G ++ T + DG++ + D+
Sbjct: 641 YVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH 700
Query: 263 GHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT--NFTDLSSE 310
G + L GH V ++ FS G+ +S D V +W F DL ++
Sbjct: 701 GLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETD 750
Score = 90.6 bits (215), Expect = 2e-17
Identities = 54/206 (26%), Positives = 89/206 (43%), Gaps = 6/206 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K L GH + ++P+ + +SS D +V LW L+ ++GH+ V D FS
Sbjct: 537 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 596
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
G Y S D+ R+W +F H V +F + + + T S D+ V+LW
Sbjct: 597 GYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV 656
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG-- 192
+ F GH + S +G +A+ + D LW++ G + +LKGH
Sbjct: 657 LNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMV---GELKGHTDT 713
Query: 193 -LHLAWHPSGCYVAVATSHGNVKLYD 217
L + G +A + V+L+D
Sbjct: 714 VCSLRFSRDGEILASGSMDNTVRLWD 739
>U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100
protein.
Length = 800
Score = 112 bits (269), Expect = 7e-24
Identities = 67/226 (29%), Positives = 110/226 (48%), Gaps = 9/226 (3%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
GH V +FS Y+ S+S D TVR+W + T T G +K H+ V QFS G
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG-YKGHNYPVWDTQFSPYGYY 599
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG 179
++ D+V +LW+T ++ + F GH V C R + + +A+ S D++ +LW++ +G
Sbjct: 600 FVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNG 659
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI 239
C+ + KG L + P+G ++A + G V L+DI +V H + V +
Sbjct: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 240 HPSGSYILTASKDGKMKILDL------LEGHPIFTLSGH-NGPVNA 278
G + + S D +++ D LE T +GH N P N+
Sbjct: 720 SRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENS 765
Score = 99.1 bits (236), Expect = 7e-20
Identities = 73/305 (23%), Positives = 131/305 (42%), Gaps = 16/305 (5%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGT-MRSYRFQGHDEAVM 67
P C L ++ +TA+ + IA D++V +W + +RS + Q D +++
Sbjct: 459 PSICFYTFLNAYQG-LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVK-QASDLSLI 516
Query: 68 DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK 127
D S D RI + HS V FS D + ++++S+D
Sbjct: 517 D-----------KESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDG 565
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
V+LWS + + GH V + S G S D+ +LW D + + +
Sbjct: 566 TVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAG 625
Query: 188 LKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL 247
+HP+ YVA ++ V+L+D+ N V+ ++ H + + P+G ++
Sbjct: 626 HLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLA 685
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT--NFT 305
T + DG++ + D+ G + L GH V ++ FS G+ +S D V +W F
Sbjct: 686 TGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFE 745
Query: 306 DLSSE 310
DL ++
Sbjct: 746 DLETD 750
>U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor
protein.
Length = 801
Score = 112 bits (269), Expect = 7e-24
Identities = 67/226 (29%), Positives = 110/226 (48%), Gaps = 9/226 (3%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
GH V +FS Y+ S+S D TVR+W + T T G +K H+ V QFS G
Sbjct: 542 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG-YKGHNYPVWDTQFSPYGYY 600
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG 179
++ D+V +LW+T ++ + F GH V C R + + +A+ S D++ +LW++ +G
Sbjct: 601 FVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNG 660
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI 239
C+ + KG L + P+G ++A + G V L+DI +V H + V +
Sbjct: 661 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 720
Query: 240 HPSGSYILTASKDGKMKILDL------LEGHPIFTLSGH-NGPVNA 278
G + + S D +++ D LE T +GH N P N+
Sbjct: 721 SRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENS 766
Score = 99.1 bits (236), Expect = 7e-20
Identities = 73/305 (23%), Positives = 131/305 (42%), Gaps = 16/305 (5%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGT-MRSYRFQGHDEAVM 67
P C L ++ +TA+ + IA D++V +W + +RS + Q D +++
Sbjct: 460 PSICFYTFLNAYQG-LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVK-QASDLSLI 517
Query: 68 DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK 127
D S D RI + HS V FS D + ++++S+D
Sbjct: 518 D-----------KESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDG 566
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
V+LWS + + GH V + S G S D+ +LW D + + +
Sbjct: 567 TVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAG 626
Query: 188 LKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL 247
+HP+ YVA ++ V+L+D+ N V+ ++ H + + P+G ++
Sbjct: 627 HLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLA 686
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT--NFT 305
T + DG++ + D+ G + L GH V ++ FS G+ +S D V +W F
Sbjct: 687 TGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFE 746
Query: 306 DLSSE 310
DL ++
Sbjct: 747 DLETD 751
>BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 112 bits (269), Expect = 7e-24
Identities = 67/226 (29%), Positives = 110/226 (48%), Gaps = 9/226 (3%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
GH V +FS Y+ S+S D TVR+W + T T G +K H+ V QFS G
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG-YKGHNYPVWDTQFSPYGYY 599
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG 179
++ D+V +LW+T ++ + F GH V C R + + +A+ S D++ +LW++ +G
Sbjct: 600 FVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNG 659
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI 239
C+ + KG L + P+G ++A + G V L+DI +V H + V +
Sbjct: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 240 HPSGSYILTASKDGKMKILDL------LEGHPIFTLSGH-NGPVNA 278
G + + S D +++ D LE T +GH N P N+
Sbjct: 720 SRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENS 765
Score = 99.1 bits (236), Expect = 7e-20
Identities = 73/305 (23%), Positives = 131/305 (42%), Gaps = 16/305 (5%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGT-MRSYRFQGHDEAVM 67
P C L ++ +TA+ + IA D++V +W + +RS + Q D +++
Sbjct: 459 PSICFYTFLNAYQG-LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVK-QASDLSLI 516
Query: 68 DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK 127
D S D RI + HS V FS D + ++++S+D
Sbjct: 517 D-----------KESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDG 565
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
V+LWS + + GH V + S G S D+ +LW D + + +
Sbjct: 566 TVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAG 625
Query: 188 LKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL 247
+HP+ YVA ++ V+L+D+ N V+ ++ H + + P+G ++
Sbjct: 626 HLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLA 685
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT--NFT 305
T + DG++ + D+ G + L GH V ++ FS G+ +S D V +W F
Sbjct: 686 TGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFE 745
Query: 306 DLSSE 310
DL ++
Sbjct: 746 DLETD 750
>AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 112 bits (269), Expect = 7e-24
Identities = 67/226 (29%), Positives = 110/226 (48%), Gaps = 9/226 (3%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
GH V +FS Y+ S+S D TVR+W + T T G +K H+ V QFS G
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG-YKGHNYPVWDTQFSPYGYY 599
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG 179
++ D+V +LW+T ++ + F GH V C R + + +A+ S D++ +LW++ +G
Sbjct: 600 FVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNG 659
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI 239
C+ + KG L + P+G ++A + G V L+DI +V H + V +
Sbjct: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 240 HPSGSYILTASKDGKMKILDL------LEGHPIFTLSGH-NGPVNA 278
G + + S D +++ D LE T +GH N P N+
Sbjct: 720 SRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENS 765
Score = 99.1 bits (236), Expect = 7e-20
Identities = 73/305 (23%), Positives = 131/305 (42%), Gaps = 16/305 (5%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGT-MRSYRFQGHDEAVM 67
P C L ++ +TA+ + IA D++V +W + +RS + Q D +++
Sbjct: 459 PSICFYTFLNAYQG-LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVK-QASDLSLI 516
Query: 68 DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK 127
D S D RI + HS V FS D + ++++S+D
Sbjct: 517 D-----------KESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDG 565
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
V+LWS + + GH V + S G S D+ +LW D + + +
Sbjct: 566 TVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAG 625
Query: 188 LKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL 247
+HP+ YVA ++ V+L+D+ N V+ ++ H + + P+G ++
Sbjct: 626 HLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLA 685
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT--NFT 305
T + DG++ + D+ G + L GH V ++ FS G+ +S D V +W F
Sbjct: 686 TGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFE 745
Query: 306 DLSSE 310
DL ++
Sbjct: 746 DLETD 750
>AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiation
factor TFIID subunit 5 variant protein.
Length = 803
Score = 112 bits (269), Expect = 7e-24
Identities = 67/226 (29%), Positives = 110/226 (48%), Gaps = 9/226 (3%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
GH V +FS Y+ S+S D TVR+W + T T G +K H+ V QFS G
Sbjct: 544 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG-YKGHNYPVWDTQFSPYGYY 602
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG 179
++ D+V +LW+T ++ + F GH V C R + + +A+ S D++ +LW++ +G
Sbjct: 603 FVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNG 662
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI 239
C+ + KG L + P+G ++A + G V L+DI +V H + V +
Sbjct: 663 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 722
Query: 240 HPSGSYILTASKDGKMKILDL------LEGHPIFTLSGH-NGPVNA 278
G + + S D +++ D LE T +GH N P N+
Sbjct: 723 SRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENS 768
Score = 99.1 bits (236), Expect = 7e-20
Identities = 73/305 (23%), Positives = 131/305 (42%), Gaps = 16/305 (5%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGT-MRSYRFQGHDEAVM 67
P C L ++ +TA+ + IA D++V +W + +RS + Q D +++
Sbjct: 462 PSICFYTFLNAYQG-LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVK-QASDLSLI 519
Query: 68 DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK 127
D S D RI + HS V FS D + ++++S+D
Sbjct: 520 D-----------KESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDG 568
Query: 128 VVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
V+LWS + + GH V + S G S D+ +LW D + + +
Sbjct: 569 TVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAG 628
Query: 188 LKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL 247
+HP+ YVA ++ V+L+D+ N V+ ++ H + + P+G ++
Sbjct: 629 HLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLA 688
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT--NFT 305
T + DG++ + D+ G + L GH V ++ FS G+ +S D V +W F
Sbjct: 689 TGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFE 748
Query: 306 DLSSE 310
DL ++
Sbjct: 749 DLETD 753
>BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein.
Length = 571
Score = 111 bits (267), Expect = 1e-23
Identities = 69/238 (28%), Positives = 114/238 (47%), Gaps = 1/238 (0%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + ++ ++P+ ++ATSS D +V LWDL F+GH AV T+ S G ++
Sbjct: 332 GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFV 391
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHK 138
AS+S DKT +IW H+ +V S++F + ++T+S DK + +W
Sbjct: 392 ASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGI 451
Query: 139 FISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWH 198
S GH + + A G +IASC TKLW+ I + G + +
Sbjct: 452 CEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFD 511
Query: 199 PSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMK 256
SG +A A+ +G + L D+++ + + NEA T V H G + + DG ++
Sbjct: 512 SSGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVVFSH-DGEILFSGGSDGTVR 568
Score = 100 bits (239), Expect = 3e-20
Identities = 77/293 (26%), Positives = 130/293 (44%), Gaps = 11/293 (3%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ---GHDEAVMDV 69
LK + H+ ++ + +P+ + + D LW + G + GH + + D
Sbjct: 284 LKNIFRLHELPVSCVSMHPHKDILVSCGEDR---LWKVLGLPKCNVLLTGFGHTDWLSDC 340
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVV 129
F SG +A++S D TV++W F+ HS+ V S + S G+ + ++S DK
Sbjct: 341 CFHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTS 400
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT-YKDL 188
K+W + + + GHT+ V + + + S DK+ +W+ +G C + Y +
Sbjct: 401 KIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHM 460
Query: 189 KGHGLHLA-WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL 247
H ++ A + P G +A + G KL+D R + I +V SG +
Sbjct: 461 --HSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLA 518
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
AS +G + +LDL G I L GH + V FS G+ S G D V W
Sbjct: 519 QASGNGVIHLLDLKSGE-IHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTW 570
Score = 79.4 bits (187), Expect = 6e-14
Identities = 52/218 (23%), Positives = 93/218 (42%), Gaps = 1/218 (0%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
H+ + F G K+ T+S D VKLW K I +F GH+ V + G+ +A
Sbjct: 333 HTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVA 392
Query: 164 SCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNL 223
S S DK++K+W+++S C T + + P + +++ + ++D RT
Sbjct: 393 SSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGIC 452
Query: 224 VQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSP 283
Q H ++ P G I + G K+ D + PI ++ P N VNF
Sbjct: 453 EQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDS 512
Query: 284 TGDTFSSAGDDKLVFIWKTNFTDLSS-ESKENEGQNMI 320
+G + A + ++ + ++ ENE ++
Sbjct: 513 SGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVV 550
Score = 71.7 bits (168), Expect = 1e-11
Identities = 45/164 (27%), Positives = 74/164 (45%)
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
+K + F H V C M I+ SC +D+ K+ L + T
Sbjct: 282 YKLKNIFRLHELPVSCVSMHPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCC 341
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMK 256
+HPSG +A ++ VKL+D+ + + + H+ AV H G+++ ++S D K
Sbjct: 342 FHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSK 401
Query: 257 ILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
I D+ TL GH VN++ F P +T ++ DK + IW
Sbjct: 402 IWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIW 445
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/164 (25%), Positives = 70/164 (42%), Gaps = 11/164 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH +++ ++ + P + TSS D ++ +WD R + GH ++ D F G
Sbjct: 414 LYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGH 473
Query: 77 YMASASRDKTVRIW-----VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+AS ++W +P V+ G + V F S G + AS + V+ L
Sbjct: 474 MIASCDACGVTKLWDFRKLLPIVSIDIGPSPGN-----EVNFDSSGRVLAQASGNGVIHL 528
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K I +GH N S+DG I+ S D + + W+
Sbjct: 529 LDL-KSGEIHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS 571
>AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD repeat
protein protein.
Length = 631
Score = 111 bits (267), Expect = 1e-23
Identities = 69/238 (28%), Positives = 114/238 (47%), Gaps = 1/238 (0%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + ++ ++P+ ++ATSS D +V LWDL F+GH AV T+ S G ++
Sbjct: 392 GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFV 451
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHK 138
AS+S DKT +IW H+ +V S++F + ++T+S DK + +W
Sbjct: 452 ASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGI 511
Query: 139 FISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWH 198
S GH + + A G +IASC TKLW+ I + G + +
Sbjct: 512 CEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFD 571
Query: 199 PSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMK 256
SG +A A+ +G + L D+++ + + NEA T V H G + + DG ++
Sbjct: 572 SSGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVVFSH-DGEILFSGGSDGTVR 628
Score = 100 bits (240), Expect = 2e-20
Identities = 69/242 (28%), Positives = 111/242 (45%), Gaps = 5/242 (2%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKI 120
GH + + D F SG +A++S D TV++W F+ HS+ V S + S G+ +
Sbjct: 392 GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFV 451
Query: 121 ITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGE 180
++S DK K+W + + + GHT+ V + + + S DK+ +W+ +G
Sbjct: 452 ASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGI 511
Query: 181 CIHT-YKDLKGHGLHLA-WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
C + Y + H ++ A + P G +A + G KL+D R + I +V
Sbjct: 512 CEQSLYGHM--HSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVN 569
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVF 298
SG + AS +G + +LDL G I L GH + V FS G+ S G D V
Sbjct: 570 FDSSGRVLAQASGNGVIHLLDLKSGE-IHKLMGHENEAHTVVFSHDGEILFSGGSDGTVR 628
Query: 299 IW 300
W
Sbjct: 629 TW 630
Score = 86.6 bits (205), Expect = 4e-16
Identities = 49/201 (24%), Positives = 89/201 (44%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDG 159
+F+ H V V +++ +D++ K+ K + + GHT+W+ G
Sbjct: 347 IFRLHELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSG 406
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+A+ S D + KLW+L +G+CI T++ WH G +VA ++ K++D+
Sbjct: 407 DKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVN 466
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
+ H ++V + P + +LT+S D + I D G +L GH +N
Sbjct: 467 SERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDA 526
Query: 280 NFSPTGDTFSSAGDDKLVFIW 300
F P G +S + +W
Sbjct: 527 IFDPRGHMIASCDACGVTKLW 547
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/218 (23%), Positives = 92/218 (42%), Gaps = 1/218 (0%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
H+ + F G K+ T+S D VKLW I +F GH+ V + G+ +A
Sbjct: 393 HTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVA 452
Query: 164 SCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNL 223
S S DK++K+W+++S C T + + P + +++ + ++D RT
Sbjct: 453 SSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGIC 512
Query: 224 VQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSP 283
Q H ++ P G I + G K+ D + PI ++ P N VNF
Sbjct: 513 EQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDS 572
Query: 284 TGDTFSSAGDDKLVFIWKTNFTDLSS-ESKENEGQNMI 320
+G + A + ++ + ++ ENE ++
Sbjct: 573 SGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVV 610
Score = 74.5 bits (175), Expect = 2e-12
Identities = 46/164 (28%), Positives = 75/164 (45%)
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
+K + F H V C M I+ SC +D+ K+ L + T
Sbjct: 342 YKLKNIFRLHELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCC 401
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMK 256
+HPSG +A ++ VKL+D+ T + + + H+ AV H G+++ ++S D K
Sbjct: 402 FHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSK 461
Query: 257 ILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
I D+ TL GH VN++ F P +T ++ DK + IW
Sbjct: 462 IWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIW 505
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/164 (25%), Positives = 70/164 (42%), Gaps = 11/164 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH +++ ++ + P + TSS D ++ +WD R + GH ++ D F G
Sbjct: 474 LYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGH 533
Query: 77 YMASASRDKTVRIW-----VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+AS ++W +P V+ G + V F S G + AS + V+ L
Sbjct: 534 MIASCDACGVTKLWDFRKLLPIVSIDIGPSPGN-----EVNFDSSGRVLAQASGNGVIHL 588
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K I +GH N S+DG I+ S D + + W+
Sbjct: 589 LDL-KSGEIHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS 631
Score = 58.8 bits (136), Expect = 9e-08
Identities = 44/174 (25%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH A+ + ++ +A+SSLD + +WD+ GH ++V + F
Sbjct: 433 EGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNT 492
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ ++S DKT+ IW H ++ F G I + V KLW K
Sbjct: 493 LLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKL 552
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
I S + + G ++A S + L +L SGE IH L GH
Sbjct: 553 LPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGE-IH---KLMGH 602
Score = 52.8 bits (121), Expect = 6e-06
Identities = 30/120 (25%), Positives = 50/120 (41%), Gaps = 1/120 (0%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L GH ++I ++P IA+ LWD R + +V F S
Sbjct: 513 EQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDS 572
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
SG+ +A AS + + + + +G H +V FS DG + + D V+ WS
Sbjct: 573 SGRVLAQASGNGVIHL-LDLKSGEIHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS 631
>AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein.
Length = 631
Score = 111 bits (267), Expect = 1e-23
Identities = 69/238 (28%), Positives = 114/238 (47%), Gaps = 1/238 (0%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + ++ ++P+ ++ATSS D +V LWDL F+GH AV T+ S G ++
Sbjct: 392 GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFV 451
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHK 138
AS+S DKT +IW H+ +V S++F + ++T+S DK + +W
Sbjct: 452 ASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGI 511
Query: 139 FISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWH 198
S GH + + A G +IASC TKLW+ I + G + +
Sbjct: 512 CEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFD 571
Query: 199 PSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMK 256
SG +A A+ +G + L D+++ + + NEA T V H G + + DG ++
Sbjct: 572 SSGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVVFSH-DGEILFSGGSDGTVR 628
Score = 100 bits (240), Expect = 2e-20
Identities = 69/242 (28%), Positives = 111/242 (45%), Gaps = 5/242 (2%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKI 120
GH + + D F SG +A++S D TV++W F+ HS+ V S + S G+ +
Sbjct: 392 GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFV 451
Query: 121 ITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGE 180
++S DK K+W + + + GHT+ V + + + S DK+ +W+ +G
Sbjct: 452 ASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGI 511
Query: 181 CIHT-YKDLKGHGLHLA-WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
C + Y + H ++ A + P G +A + G KL+D R + I +V
Sbjct: 512 CEQSLYGHM--HSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVN 569
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVF 298
SG + AS +G + +LDL G I L GH + V FS G+ S G D V
Sbjct: 570 FDSSGRVLAQASGNGVIHLLDLKSGE-IHKLMGHENEAHTVVFSHDGEILFSGGSDGTVR 628
Query: 299 IW 300
W
Sbjct: 629 TW 630
Score = 86.6 bits (205), Expect = 4e-16
Identities = 49/201 (24%), Positives = 89/201 (44%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDG 159
+F+ H V V +++ +D++ K+ K + + GHT+W+ G
Sbjct: 347 IFRLHELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSG 406
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+A+ S D + KLW+L +G+CI T++ WH G +VA ++ K++D+
Sbjct: 407 DKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVN 466
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
+ H ++V + P + +LT+S D + I D G +L GH +N
Sbjct: 467 SERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDA 526
Query: 280 NFSPTGDTFSSAGDDKLVFIW 300
F P G +S + +W
Sbjct: 527 IFDPRGHMIASCDACGVTKLW 547
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/218 (23%), Positives = 92/218 (42%), Gaps = 1/218 (0%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
H+ + F G K+ T+S D VKLW I +F GH+ V + G+ +A
Sbjct: 393 HTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVA 452
Query: 164 SCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNL 223
S S DK++K+W+++S C T + + P + +++ + ++D RT
Sbjct: 453 SSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGIC 512
Query: 224 VQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSP 283
Q H ++ P G I + G K+ D + PI ++ P N VNF
Sbjct: 513 EQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDS 572
Query: 284 TGDTFSSAGDDKLVFIWKTNFTDLSS-ESKENEGQNMI 320
+G + A + ++ + ++ ENE ++
Sbjct: 573 SGRVLAQASGNGVIHLLDLKSGEIHKLMGHENEAHTVV 610
Score = 74.5 bits (175), Expect = 2e-12
Identities = 46/164 (28%), Positives = 75/164 (45%)
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
+K + F H V C M I+ SC +D+ K+ L + T
Sbjct: 342 YKLKNIFRLHELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCC 401
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMK 256
+HPSG +A ++ VKL+D+ T + + + H+ AV H G+++ ++S D K
Sbjct: 402 FHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSK 461
Query: 257 ILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
I D+ TL GH VN++ F P +T ++ DK + IW
Sbjct: 462 IWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIW 505
Score = 62.9 bits (146), Expect = 5e-09
Identities = 42/164 (25%), Positives = 70/164 (42%), Gaps = 11/164 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH +++ ++ + P + TSS D ++ +WD R + GH ++ D F G
Sbjct: 474 LYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGH 533
Query: 77 YMASASRDKTVRIW-----VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+AS ++W +P V+ G + V F S G + AS + V+ L
Sbjct: 534 MIASCDACGVTKLWDFRKLLPIVSIDIGPSPGN-----EVNFDSSGRVLAQASGNGVIHL 588
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K I +GH N S+DG I+ S D + + W+
Sbjct: 589 LDL-KSGEIHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS 631
Score = 58.8 bits (136), Expect = 9e-08
Identities = 44/174 (25%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH A+ + ++ +A+SSLD + +WD+ GH ++V + F
Sbjct: 433 EGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNT 492
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ ++S DKT+ IW H ++ F G I + V KLW K
Sbjct: 493 LLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKL 552
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
I S + + G ++A S + L +L SGE IH L GH
Sbjct: 553 LPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGE-IH---KLMGH 602
Score = 52.8 bits (121), Expect = 6e-06
Identities = 30/120 (25%), Positives = 50/120 (41%), Gaps = 1/120 (0%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L GH ++I ++P IA+ LWD R + +V F S
Sbjct: 513 EQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDS 572
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
SG+ +A AS + + + + +G H +V FS DG + + D V+ WS
Sbjct: 573 SGRVLAQASGNGVIHL-LDLKSGEIHKLMGHENEAHTVVFSHDGEILFSGGSDGTVRTWS 631
>BC113421-1|AAI13422.1| 514|Homo sapiens transducin (beta)-like
1X-linked receptor 1 protein.
Length = 514
Score = 109 bits (262), Expect = 5e-23
Identities = 75/288 (26%), Positives = 128/288 (44%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N +AT S D +W G + S Q H + + ++ G ++ SA
Sbjct: 228 VTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQ-HKGPIFALKWNKKGNFILSAGV 286
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + S+ + + S D + + + + I +F
Sbjct: 287 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNT-FASCSTDMCIHVCKLGQDRPIKTF 345
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G+++ASCSDD + K+W++ C+H DL+ H + W P+
Sbjct: 346 QGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVH---DLQAHNKEIYTIKWSPT 402
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+D+ + + H E V VA P G Y+ + S
Sbjct: 403 GPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSF 462
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G + + G G + V ++ GD ++ D V +
Sbjct: 463 DKCVHIWNTQTGALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCV 509
Score = 100 bits (240), Expect = 2e-20
Identities = 64/265 (24%), Positives = 120/265 (45%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T + L L HK I AL +N I ++ +D + ++WD +F H
Sbjct: 250 RIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSA 309
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + S+ + AS S D + + F+ H+ V ++++ G+ + + S
Sbjct: 310 PALDVDWQSNNTF-ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCS 368
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + + H + + S N ++AS S D + +LW+
Sbjct: 369 DDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD 428
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
+D G CIHT + +A+ P G Y+A + V +++ +T LV Y +
Sbjct: 429 VDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYR-GTGGIF 487
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + +G + ++ DG + +LDL
Sbjct: 488 EVCWNAAGDKVGASASDGSVCVLDL 512
Score = 96.7 bits (230), Expect = 3e-19
Identities = 77/310 (24%), Positives = 135/310 (43%), Gaps = 27/310 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L S Q G D
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++S G +A+ S D RIW T G+ H + +++++ G+ I+
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW--TKDGNLASTLGQHKGPIFALKWNKKGNFIL 282
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ ++ + ASCS D + L
Sbjct: 283 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTF-ASCSTDMCIHVCKLGQDRP 341
Query: 182 IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
I T++ + W P+G +A + +K++ ++ N V HN+ + + P
Sbjct: 342 IKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSP 401
Query: 242 SGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+G + +AS D +++ D+ G I TL+ H PV +V FSP G +S
Sbjct: 402 TGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGS 461
Query: 293 DDKLVFIWKT 302
DK V IW T
Sbjct: 462 FDKCVHIWNT 471
Score = 82.6 bits (195), Expect = 6e-15
Identities = 56/215 (26%), Positives = 95/215 (44%), Gaps = 11/215 (5%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
K+Q H + + N+ A+ S D + + L FQGH V + +
Sbjct: 301 KQQFPFHSAPALDVDWQSNNT-FASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDP 359
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS---------KIITAS 124
+G +AS S D T++IW +AH++ + ++++S G + +AS
Sbjct: 360 TGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASAS 419
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
D V+LW + I + H V S DG +AS S DK +WN +G +H+
Sbjct: 420 FDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHS 479
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
Y+ G + W+ +G V + S G+V + D+R
Sbjct: 480 YRGTGGI-FEVCWNAAGDKVGASASDGSVCVLDLR 513
>BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 4 protein.
Length = 340
Score = 109 bits (262), Expect = 5e-23
Identities = 71/293 (24%), Positives = 133/293 (45%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D S+I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDD-SQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GH+ V +S D S + D S+KLW++ G C ++
Sbjct: 167 ALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHV 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+++ P+G A + +L+D+R + YS N +T VA SG +L
Sbjct: 227 SDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D L+G L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIW 339
Score = 77.0 bits (181), Expect = 3e-13
Identities = 57/256 (22%), Positives = 104/256 (40%), Gaps = 8/256 (3%)
Query: 54 MRSYR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
MR+ R +GH + + + + + SAS+D + IW T S V +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCA 104
Query: 113 FSSDGSKIITASDDKVVKLWSTHKH----KFISSFVGHTNWVRCARMSNDGSIIASCSDD 168
++ G+ + D + +++ + GHT ++ C R +D I+ S S D
Sbjct: 105 YAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTS-SGD 163
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS 228
+ LW++++ + T+ G + L+ P + KL+DIR Q ++
Sbjct: 164 TTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFT 223
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN--GPVNAVNFSPTGD 286
H + V+ P+G T S D ++ DL + S N + +V FS +G
Sbjct: 224 GHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGR 283
Query: 287 TFSSAGDDKLVFIWKT 302
+ DD +W T
Sbjct: 284 LLLAGYDDFNCNVWDT 299
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 73/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L +P+ + + + D S LWD+R M F GH + V+F +G
Sbjct: 182 GHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ ++ +H + SV FS G ++ DD +W T
Sbjct: 242 ATGSDDATCRLFDLRADQELLLY-SHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D ++WN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
>AK022956-1|BAB14331.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ12894 fis, clone NT2RP2004170, moderately
similar to Homo sapiens mRNA for transducin (beta) like
1 protein. ).
Length = 514
Score = 109 bits (262), Expect = 5e-23
Identities = 75/288 (26%), Positives = 128/288 (44%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N +AT S D +W G + S Q H + + ++ G ++ SA
Sbjct: 228 VTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQ-HKGPIFALKWNKKGNFILSAGV 286
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + S+ + + S D + + + + I +F
Sbjct: 287 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNT-FASCSTDMCIHVCKLGQDRPIKTF 345
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G+++ASCSDD + K+W++ C+H DL+ H + W P+
Sbjct: 346 QGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVH---DLQAHNKEIYTIKWSPT 402
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+D+ + + H E V VA P G Y+ + S
Sbjct: 403 GPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSF 462
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G + + G G + V ++ GD ++ D V +
Sbjct: 463 DKCVHIWNTQTGALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCV 509
Score = 100 bits (240), Expect = 2e-20
Identities = 64/265 (24%), Positives = 120/265 (45%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T + L L HK I AL +N I ++ +D + ++WD +F H
Sbjct: 250 RIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSA 309
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + S+ + AS S D + + F+ H+ V ++++ G+ + + S
Sbjct: 310 PALDVDWQSNNTF-ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCS 368
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + + H + + S N ++AS S D + +LW+
Sbjct: 369 DDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD 428
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
+D G CIHT + +A+ P G Y+A + V +++ +T LV Y +
Sbjct: 429 VDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYR-GTGGIF 487
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + +G + ++ DG + +LDL
Sbjct: 488 EVCWNAAGDKVGASASDGSVCVLDL 512
Score = 96.7 bits (230), Expect = 3e-19
Identities = 77/310 (24%), Positives = 135/310 (43%), Gaps = 27/310 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L S Q G D
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++S G +A+ S D RIW T G+ H + +++++ G+ I+
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW--TKDGNLASTLGQHKGPIFALKWNKKGNFIL 282
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ ++ + ASCS D + L
Sbjct: 283 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTF-ASCSTDMCIHVCKLGQDRP 341
Query: 182 IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
I T++ + W P+G +A + +K++ ++ N V HN+ + + P
Sbjct: 342 IKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSP 401
Query: 242 SGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+G + +AS D +++ D+ G I TL+ H PV +V FSP G +S
Sbjct: 402 TGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGS 461
Query: 293 DDKLVFIWKT 302
DK V IW T
Sbjct: 462 FDKCVHIWNT 471
Score = 82.6 bits (195), Expect = 6e-15
Identities = 56/215 (26%), Positives = 95/215 (44%), Gaps = 11/215 (5%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
K+Q H + + N+ A+ S D + + L FQGH V + +
Sbjct: 301 KQQFPFHSAPALDVDWQSNNT-FASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDP 359
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS---------KIITAS 124
+G +AS S D T++IW +AH++ + ++++S G + +AS
Sbjct: 360 TGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASAS 419
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
D V+LW + I + H V S DG +AS S DK +WN +G +H+
Sbjct: 420 FDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHS 479
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
Y+ G + W+ +G V + S G+V + D+R
Sbjct: 480 YRGTGGI-FEVCWNAAGDKVGASASDGSVCVLDLR 513
>AF314544-1|AAK00301.1| 514|Homo sapiens nuclear receptor
co-repressor/HDAC3 complex subunit TBLR1 protein.
Length = 514
Score = 109 bits (262), Expect = 5e-23
Identities = 75/288 (26%), Positives = 128/288 (44%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N +AT S D +W G + S Q H + + ++ G ++ SA
Sbjct: 228 VTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQ-HKGPIFALKWNKKGNFILSAGV 286
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + S+ + + S D + + + + I +F
Sbjct: 287 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNT-FASCSTDMCIHVCKLGQDRPIKTF 345
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G+++ASCSDD + K+W++ C+H DL+ H + W P+
Sbjct: 346 QGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVH---DLQAHNKEIYTIKWSPT 402
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+D+ + + H E V VA P G Y+ + S
Sbjct: 403 GPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSF 462
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G + + G G + V ++ GD ++ D V +
Sbjct: 463 DKCVHIWNTQTGALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCV 509
Score = 100 bits (240), Expect = 2e-20
Identities = 64/265 (24%), Positives = 120/265 (45%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T + L L HK I AL +N I ++ +D + ++WD +F H
Sbjct: 250 RIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSA 309
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + S+ + AS S D + + F+ H+ V ++++ G+ + + S
Sbjct: 310 PALDVDWQSNNTF-ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCS 368
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + + H + + S N ++AS S D + +LW+
Sbjct: 369 DDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD 428
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
+D G CIHT + +A+ P G Y+A + V +++ +T LV Y +
Sbjct: 429 VDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYR-GTGGIF 487
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + +G + ++ DG + +LDL
Sbjct: 488 EVCWNAAGDKVGASASDGSVCVLDL 512
Score = 96.7 bits (230), Expect = 3e-19
Identities = 77/310 (24%), Positives = 135/310 (43%), Gaps = 27/310 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L S Q G D
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++S G +A+ S D RIW T G+ H + +++++ G+ I+
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW--TKDGNLASTLGQHKGPIFALKWNKKGNFIL 282
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ ++ + ASCS D + L
Sbjct: 283 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTF-ASCSTDMCIHVCKLGQDRP 341
Query: 182 IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
I T++ + W P+G +A + +K++ ++ N V HN+ + + P
Sbjct: 342 IKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSP 401
Query: 242 SGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+G + +AS D +++ D+ G I TL+ H PV +V FSP G +S
Sbjct: 402 TGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGS 461
Query: 293 DDKLVFIWKT 302
DK V IW T
Sbjct: 462 FDKCVHIWNT 471
Score = 82.6 bits (195), Expect = 6e-15
Identities = 56/215 (26%), Positives = 95/215 (44%), Gaps = 11/215 (5%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
K+Q H + + N+ A+ S D + + L FQGH V + +
Sbjct: 301 KQQFPFHSAPALDVDWQSNNT-FASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDP 359
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS---------KIITAS 124
+G +AS S D T++IW +AH++ + ++++S G + +AS
Sbjct: 360 TGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASAS 419
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
D V+LW + I + H V S DG +AS S DK +WN +G +H+
Sbjct: 420 FDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHS 479
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
Y+ G + W+ +G V + S G+V + D+R
Sbjct: 480 YRGTGGI-FEVCWNAAGDKVGASASDGSVCVLDLR 513
>AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide binding
protein beta subunit 4 protein.
Length = 340
Score = 109 bits (262), Expect = 5e-23
Identities = 71/293 (24%), Positives = 133/293 (45%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D S+I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDD-SQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GH+ V +S D S + D S+KLW++ G C ++
Sbjct: 167 ALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHV 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+++ P+G A + +L+D+R + YS N +T VA SG +L
Sbjct: 227 SDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D L+G L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIW 339
Score = 77.0 bits (181), Expect = 3e-13
Identities = 57/256 (22%), Positives = 104/256 (40%), Gaps = 8/256 (3%)
Query: 54 MRSYR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
MR+ R +GH + + + + + SAS+D + IW T S V +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCA 104
Query: 113 FSSDGSKIITASDDKVVKLWSTHKH----KFISSFVGHTNWVRCARMSNDGSIIASCSDD 168
++ G+ + D + +++ + GHT ++ C R +D I+ S S D
Sbjct: 105 YAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTS-SGD 163
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS 228
+ LW++++ + T+ G + L+ P + KL+DIR Q ++
Sbjct: 164 TTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFT 223
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN--GPVNAVNFSPTGD 286
H + V+ P+G T S D ++ DL + S N + +V FS +G
Sbjct: 224 GHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGR 283
Query: 287 TFSSAGDDKLVFIWKT 302
+ DD +W T
Sbjct: 284 LLLAGYDDFNCNVWDT 299
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 73/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L +P+ + + + D S LWD+R M F GH + V+F +G
Sbjct: 182 GHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ ++ +H + SV FS G ++ DD +W T
Sbjct: 242 ATGSDDATCRLFDLRADQELLLY-SHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D ++WN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
>AF268193-1|AAG44736.1| 514|Homo sapiens IRA1 protein.
Length = 514
Score = 109 bits (262), Expect = 5e-23
Identities = 72/285 (25%), Positives = 125/285 (43%), Gaps = 12/285 (4%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N +AT S D +W G + S Q H + + ++ G ++ SA
Sbjct: 228 VTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQ-HKGPIFALKWNKKGNFILSAGV 286
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + S+ + + S D + + + + I +F
Sbjct: 287 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNT-FASCSTDMCIHVCKLGQDRPIKTF 345
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSG-- 201
GHTN V + G+++ASCSDD + K+W++ C+H + + W P+G
Sbjct: 346 QGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQQHNKEIYTIKWSPTGPG 405
Query: 202 -------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGK 254
+A A+ V+L+D+ + + H E V VA P G Y+ + S D
Sbjct: 406 TNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKC 465
Query: 255 MKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
+ I + G + + G G + V ++ GD ++ D V +
Sbjct: 466 VHIWNTQTGALVHSYRG-TGGIFEVCWNAAGDKVGASASDGSVCV 509
Score = 99 bits (238), Expect = 4e-20
Identities = 64/265 (24%), Positives = 120/265 (45%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T + L L HK I AL +N I ++ +D + ++WD +F H
Sbjct: 250 RIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSA 309
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + S+ + AS S D + + F+ H+ V ++++ G+ + + S
Sbjct: 310 PALDVDWQSNNTF-ASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCS 368
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + + H + + S N ++AS S D + +LW+
Sbjct: 369 DDMTLKIWSMKQDNCVHDLQQHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD 428
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
+D G CIHT + +A+ P G Y+A + V +++ +T LV Y +
Sbjct: 429 VDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYR-GTGGIF 487
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + +G + ++ DG + +LDL
Sbjct: 488 EVCWNAAGDKVGASASDGSVCVLDL 512
Score = 95.9 bits (228), Expect = 6e-19
Identities = 77/310 (24%), Positives = 135/310 (43%), Gaps = 27/310 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L S Q G D
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++S G +A+ S D RIW T G+ H + +++++ G+ I+
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIW--TKDGNLASTLGQHKGPIFALKWNKKGNFIL 282
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ ++ + ASCS D + L
Sbjct: 283 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTF-ASCSTDMCIHVCKLGQDRP 341
Query: 182 IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
I T++ + W P+G +A + +K++ ++ N V HN+ + + P
Sbjct: 342 IKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQQHNKEIYTIKWSP 401
Query: 242 SGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+G + +AS D +++ D+ G I TL+ H PV +V FSP G +S
Sbjct: 402 TGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGS 461
Query: 293 DDKLVFIWKT 302
DK V IW T
Sbjct: 462 FDKCVHIWNT 471
Score = 80.6 bits (190), Expect = 2e-14
Identities = 55/215 (25%), Positives = 94/215 (43%), Gaps = 11/215 (5%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
K+Q H + + N+ A+ S D + + L FQGH V + +
Sbjct: 301 KQQFPFHSAPALDVDWQSNNT-FASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDP 359
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS---------KIITAS 124
+G +AS S D T++IW + H++ + ++++S G + +AS
Sbjct: 360 TGNLLASCSDDMTLKIWSMKQDNCVHDLQQHNKEIYTIKWSPTGPGTNNPNANLMLASAS 419
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
D V+LW + I + H V S DG +AS S DK +WN +G +H+
Sbjct: 420 FDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHS 479
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
Y+ G + W+ +G V + S G+V + D+R
Sbjct: 480 YRGTGGI-FEVCWNAAGDKVGASASDGSVCVLDLR 513
>Y12781-1|CAA73319.1| 577|Homo sapiens transducin (beta) like 1
protein protein.
Length = 577
Score = 109 bits (261), Expect = 6e-23
Identities = 77/288 (26%), Positives = 127/288 (44%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N N +AT S D +W G + S Q H + + ++ G Y+ SA
Sbjct: 291 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQ-HKGPIFALKWNRKGNYILSAGV 349
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + ++ + + S D + + + + +F
Sbjct: 350 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-TTFASCSTDMCIHVCRLGCDRPVKTF 408
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G ++ASCSDD + K+W++ CIH DL+ H + W P+
Sbjct: 409 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIH---DLQAHNKEIYTIKWSPT 465
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+DI + H E V VA P G Y+ + S
Sbjct: 466 GPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSF 525
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G+ + + G G + V ++ GD ++ D V +
Sbjct: 526 DKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCV 572
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/265 (23%), Positives = 118/265 (44%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T + L L HK I AL +N I ++ +D + ++WD +F H
Sbjct: 313 RIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSA 372
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + ++ + AS S D + + F+ H+ V ++++ G + + S
Sbjct: 373 PALDVDWQNNTTF-ASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCS 431
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + I H + + S N ++AS S D + +LW+
Sbjct: 432 DDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD 491
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
++ G C HT + +A+ P G Y+A + V +++ ++ NLV Y +
Sbjct: 492 IERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYR-GTGGIF 550
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + G + ++ DG + +LDL
Sbjct: 551 EVCWNARGDKVGASASDGSVCVLDL 575
Score = 97.1 bits (231), Expect = 3e-19
Identities = 75/315 (23%), Positives = 136/315 (43%), Gaps = 27/315 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L Q GHD
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++++G +A+ S D RIW T G+ H + +++++ G+ I+
Sbjct: 288 NKDVTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKWNRKGNYIL 345
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ N+ + ASCS D + L
Sbjct: 346 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-TTFASCSTDMCIHVCRLGCDRP 404
Query: 182 IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+ T++ + W PSG +A + +K++ ++ + HN+ + + P
Sbjct: 405 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSP 464
Query: 242 SGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+G + +AS D +++ D+ G TL+ H PV +V FSP G +S
Sbjct: 465 TGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGS 524
Query: 293 DDKLVFIWKTNFTDL 307
DK V IW T +L
Sbjct: 525 FDKCVHIWNTQSGNL 539
>X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRNA
for beta-subunit signal transducing proteins Gs/Gi
(beta-G). ).
Length = 340
Score = 109 bits (261), Expect = 6e-23
Identities = 69/293 (23%), Positives = 132/293 (45%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D ++I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GHT V ++ D + S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+ + P+G A + +L+D+R + YS N +T V+ SG +L
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D L+ L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S LWD+R M F GH+ + + F +G
Sbjct: 182 GHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ M +H + SV FS G ++ DD +W
Sbjct: 242 ATGSDDATCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN AT S D + L+DLR + HD + +
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W G+ H V + + DG + T S D
Sbjct: 274 TSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein.
Length = 340
Score = 109 bits (261), Expect = 6e-23
Identities = 69/293 (23%), Positives = 132/293 (45%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D ++I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GHT V ++ D + S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+ + P+G A + +L+D+R + YS N +T V+ SG +L
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D L+ L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S LWD+R M F GH+ + + F +G
Sbjct: 182 GHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ M +H + SV FS G ++ DD +W
Sbjct: 242 ATGSDDATCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN AT S D + L+DLR + HD + +
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W G+ H V + + DG + T S D
Sbjct: 274 TSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 109 bits (261), Expect = 6e-23
Identities = 69/293 (23%), Positives = 132/293 (45%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D ++I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GHT V ++ D + S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+ + P+G A + +L+D+R + YS N +T V+ SG +L
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D L+ L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S LWD+R M F GH+ + + F +G
Sbjct: 182 GHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ M +H + SV FS G ++ DD +W
Sbjct: 242 ATGSDDATCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN AT S D + L+DLR + HD + +
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W G+ H V + + DG + T S D
Sbjct: 274 TSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>BC052304-1|AAH52304.1| 577|Homo sapiens transducin (beta)-like
1X-linked protein.
Length = 577
Score = 109 bits (261), Expect = 6e-23
Identities = 77/288 (26%), Positives = 127/288 (44%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N N +AT S D +W G + S Q H + + ++ G Y+ SA
Sbjct: 291 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQ-HKGPIFALKWNRKGNYILSAGV 349
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + ++ + + S D + + + + +F
Sbjct: 350 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-TTFASCSTDMCIHVCRLGCDRPVKTF 408
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G ++ASCSDD + K+W++ CIH DL+ H + W P+
Sbjct: 409 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIH---DLQAHNKEIYTIKWSPT 465
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+DI + H E V VA P G Y+ + S
Sbjct: 466 GPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSF 525
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G+ + + G G + V ++ GD ++ D V +
Sbjct: 526 DKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCV 572
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/265 (23%), Positives = 118/265 (44%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T + L L HK I AL +N I ++ +D + ++WD +F H
Sbjct: 313 RIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSA 372
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + ++ + AS S D + + F+ H+ V ++++ G + + S
Sbjct: 373 PALDVDWQNNTTF-ASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCS 431
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + I H + + S N ++AS S D + +LW+
Sbjct: 432 DDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD 491
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
++ G C HT + +A+ P G Y+A + V +++ ++ NLV Y +
Sbjct: 492 IERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYR-GTGGIF 550
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + G + ++ DG + +LDL
Sbjct: 551 EVCWNARGDKVGASASDGSVCVLDL 575
Score = 97.1 bits (231), Expect = 3e-19
Identities = 75/315 (23%), Positives = 136/315 (43%), Gaps = 27/315 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L Q GHD
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++++G +A+ S D RIW T G+ H + +++++ G+ I+
Sbjct: 288 NKDVTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKWNRKGNYIL 345
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ N+ + ASCS D + L
Sbjct: 346 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-TTFASCSTDMCIHVCRLGCDRP 404
Query: 182 IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+ T++ + W PSG +A + +K++ ++ + HN+ + + P
Sbjct: 405 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSP 464
Query: 242 SGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+G + +AS D +++ D+ G TL+ H PV +V FSP G +S
Sbjct: 465 TGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGS 524
Query: 293 DDKLVFIWKTNFTDL 307
DK V IW T +L
Sbjct: 525 FDKCVHIWNTQSGNL 539
>BC032708-1|AAH32708.1| 526|Homo sapiens TBL1X protein protein.
Length = 526
Score = 109 bits (261), Expect = 6e-23
Identities = 77/288 (26%), Positives = 127/288 (44%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N N +AT S D +W G + S Q H + + ++ G Y+ SA
Sbjct: 240 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQ-HKGPIFALKWNRKGNYILSAGV 298
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + ++ + + S D + + + + +F
Sbjct: 299 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-TTFASCSTDMCIHVCRLGCDRPVKTF 357
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G ++ASCSDD + K+W++ CIH DL+ H + W P+
Sbjct: 358 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIH---DLQAHNKEIYTIKWSPT 414
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+DI + H E V VA P G Y+ + S
Sbjct: 415 GPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSF 474
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G+ + + G G + V ++ GD ++ D V +
Sbjct: 475 DKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCV 521
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/265 (23%), Positives = 118/265 (44%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T + L L HK I AL +N I ++ +D + ++WD +F H
Sbjct: 262 RIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSA 321
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + ++ + AS S D + + F+ H+ V ++++ G + + S
Sbjct: 322 PALDVDWQNNTTF-ASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCS 380
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + I H + + S N ++AS S D + +LW+
Sbjct: 381 DDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD 440
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
++ G C HT + +A+ P G Y+A + V +++ ++ NLV Y +
Sbjct: 441 IERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYR-GTGGIF 499
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + G + ++ DG + +LDL
Sbjct: 500 EVCWNARGDKVGASASDGSVCVLDL 524
Score = 97.1 bits (231), Expect = 3e-19
Identities = 75/315 (23%), Positives = 136/315 (43%), Gaps = 27/315 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L Q GHD
Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++++G +A+ S D RIW T G+ H + +++++ G+ I+
Sbjct: 237 NKDVTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKWNRKGNYIL 294
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ N+ + ASCS D + L
Sbjct: 295 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-TTFASCSTDMCIHVCRLGCDRP 353
Query: 182 IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+ T++ + W PSG +A + +K++ ++ + HN+ + + P
Sbjct: 354 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSP 413
Query: 242 SGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+G + +AS D +++ D+ G TL+ H PV +V FSP G +S
Sbjct: 414 TGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGS 473
Query: 293 DDKLVFIWKTNFTDL 307
DK V IW T +L
Sbjct: 474 FDKCVHIWNTQSGNL 488
>BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 109 bits (261), Expect = 6e-23
Identities = 69/293 (23%), Positives = 132/293 (45%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D ++I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GHT V ++ D + S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+ + P+G A + +L+D+R + YS N +T V+ SG +L
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D L+ L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S LWD+R M F GH+ + + F +G
Sbjct: 182 GHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ M +H + SV FS G ++ DD +W
Sbjct: 242 ATGSDDATCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN AT S D + L+DLR + HD + +
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W G+ H V + + DG + T S D
Sbjct: 274 TSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 109 bits (261), Expect = 6e-23
Identities = 69/293 (23%), Positives = 132/293 (45%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D ++I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GHT V ++ D + S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+ + P+G A + +L+D+R + YS N +T V+ SG +L
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D L+ L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S LWD+R M F GH+ + + F +G
Sbjct: 182 GHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ M +H + SV FS G ++ DD +W
Sbjct: 242 ATGSDDATCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN AT S D + L+DLR + HD + +
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W G+ H V + + DG + T S D
Sbjct: 274 TSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 109 bits (261), Expect = 6e-23
Identities = 69/293 (23%), Positives = 132/293 (45%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D ++I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GHT V ++ D + S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+ + P+G A + +L+D+R + YS N +T V+ SG +L
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D L+ L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S LWD+R M F GH+ + + F +G
Sbjct: 182 GHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ M +H + SV FS G ++ DD +W
Sbjct: 242 ATGSDDATCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN AT S D + L+DLR + HD + +
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W G+ H V + + DG + T S D
Sbjct: 274 TSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 109 bits (261), Expect = 6e-23
Identities = 69/293 (23%), Positives = 132/293 (45%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D ++I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GHT V ++ D + S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+ + P+G A + +L+D+R + YS N +T V+ SG +L
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D L+ L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S LWD+R M F GH+ + + F +G
Sbjct: 182 GHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ M +H + SV FS G ++ DD +W
Sbjct: 242 ATGSDDATCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN AT S D + L+DLR + HD + +
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W G+ H V + + DG + T S D
Sbjct: 274 TSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 109 bits (261), Expect = 6e-23
Identities = 69/293 (23%), Positives = 132/293 (45%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D ++I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GHT V ++ D + S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+ + P+G A + +L+D+R + YS N +T V+ SG +L
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D L+ L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S LWD+R M F GH+ + + F +G
Sbjct: 182 GHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ M +H + SV FS G ++ DD +W
Sbjct: 242 ATGSDDATCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN AT S D + L+DLR + HD + +
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W G+ H V + + DG + T S D
Sbjct: 274 TSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 109 bits (261), Expect = 6e-23
Identities = 71/302 (23%), Positives = 141/302 (46%), Gaps = 17/302 (5%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 670
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN V R S D ++ASCS D + KLW+ S + I+
Sbjct: 731 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 790
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQVAIH 240
+D++ +W G + VA + + L+DI T L+ + ++ H+ +
Sbjct: 791 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLFDIHTSGLLGEIHTGHHSTIQYCDFS 849
Query: 241 PSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
P + A +++ + + GH V+ V FSP G +F ++ DD+ + +W
Sbjct: 850 PQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLW 909
Query: 301 KT 302
+T
Sbjct: 910 ET 911
Score = 78.6 bits (185), Expect = 1e-13
Identities = 67/296 (22%), Positives = 129/296 (43%), Gaps = 20/296 (6%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRF--------QGHDEA 65
GH N++ ++P+D+ +A+ S D ++ LWD R ++ +F + +
Sbjct: 741 GHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVI 800
Query: 66 VMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTG-MFKAHSQTVRSVQFSSDGSKIITAS 124
V ++S+ G + A+++K + T +G G + H T++ FS + A
Sbjct: 801 VKCCSWSADGARIMVAAKNKIFLFDIHT-SGLLGEIHTGHHSTIQYCDFSPQNHLAVVAL 859
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
V+LW+T ++ GH +WV S DGS + SDD++ +LW C ++
Sbjct: 860 SQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNS 918
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGS 244
LK + + + + V ++L + RT + Y + V+ + P
Sbjct: 919 AVMLK-QEVDVVFQENEVMVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQ 974
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
YI ++G ++IL+L+ + H V + F+ T S+ DD + +W
Sbjct: 975 YIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 1030
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 970 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 1028
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 1029 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1086
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1087 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1146
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1147 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1204
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1205 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1246
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 879 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 936
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 937 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 992
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 993 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1048
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1049 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1108
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1109 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1161
>AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide binding
protein beta 1 protein.
Length = 340
Score = 109 bits (261), Expect = 6e-23
Identities = 69/293 (23%), Positives = 132/293 (45%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D ++I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GHT V ++ D + S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+ + P+G A + +L+D+R + YS N +T V+ SG +L
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D L+ L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S LWD+R M F GH+ + + F +G
Sbjct: 182 GHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ M +H + SV FS G ++ DD +W
Sbjct: 242 ATGSDDATCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN AT S D + L+DLR + HD + +
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W G+ H V + + DG + T S D
Sbjct: 274 TSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 109 bits (261), Expect = 6e-23
Identities = 71/302 (23%), Positives = 141/302 (46%), Gaps = 17/302 (5%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 670
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN V R S D ++ASCS D + KLW+ S + I+
Sbjct: 731 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 790
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQVAIH 240
+D++ +W G + VA + + L+DI T L+ + ++ H+ +
Sbjct: 791 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLFDIHTSGLLGEIHTGHHSTIQYCDFS 849
Query: 241 PSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
P + A +++ + + GH V+ V FSP G +F ++ DD+ + +W
Sbjct: 850 PQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLW 909
Query: 301 KT 302
+T
Sbjct: 910 ET 911
Score = 78.6 bits (185), Expect = 1e-13
Identities = 67/296 (22%), Positives = 129/296 (43%), Gaps = 20/296 (6%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRF--------QGHDEA 65
GH N++ ++P+D+ +A+ S D ++ LWD R ++ +F + +
Sbjct: 741 GHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVI 800
Query: 66 VMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTG-MFKAHSQTVRSVQFSSDGSKIITAS 124
V ++S+ G + A+++K + T +G G + H T++ FS + A
Sbjct: 801 VKCCSWSADGARIMVAAKNKIFLFDIHT-SGLLGEIHTGHHSTIQYCDFSPQNHLAVVAL 859
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
V+LW+T ++ GH +WV S DGS + SDD++ +LW C ++
Sbjct: 860 SQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNS 918
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGS 244
LK + + + + V ++L + RT + Y + V+ + P
Sbjct: 919 AVMLK-QEVDVVFQENEVMVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQ 974
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
YI ++G ++IL+L+ + H V + F+ T S+ DD + +W
Sbjct: 975 YIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 1030
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 970 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 1028
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 1029 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1086
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1087 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1146
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1147 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1204
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1205 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1246
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 879 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 936
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 937 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 992
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 993 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1048
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1049 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1108
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1109 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1161
>AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease
activating factor-1 long isoform APAF-1L protein.
Length = 1237
Score = 109 bits (261), Expect = 6e-23
Identities = 71/302 (23%), Positives = 141/302 (46%), Gaps = 17/302 (5%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 600 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 659
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 660 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 719
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN V R S D ++ASCS D + KLW+ S + I+
Sbjct: 720 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 779
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQVAIH 240
+D++ +W G + VA + + L+DI T L+ + ++ H+ +
Sbjct: 780 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLFDIHTSGLLGEIHTGHHSTIQYCDFS 838
Query: 241 PSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
P + A +++ + + GH V+ V FSP G +F ++ DD+ + +W
Sbjct: 839 PQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLW 898
Query: 301 KT 302
+T
Sbjct: 899 ET 900
Score = 78.6 bits (185), Expect = 1e-13
Identities = 67/296 (22%), Positives = 129/296 (43%), Gaps = 20/296 (6%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRF--------QGHDEA 65
GH N++ ++P+D+ +A+ S D ++ LWD R ++ +F + +
Sbjct: 730 GHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVI 789
Query: 66 VMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTG-MFKAHSQTVRSVQFSSDGSKIITAS 124
V ++S+ G + A+++K + T +G G + H T++ FS + A
Sbjct: 790 VKCCSWSADGARIMVAAKNKIFLFDIHT-SGLLGEIHTGHHSTIQYCDFSPQNHLAVVAL 848
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
V+LW+T ++ GH +WV S DGS + SDD++ +LW C ++
Sbjct: 849 SQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNS 907
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGS 244
LK + + + + V ++L + RT + Y + V+ + P
Sbjct: 908 AVMLK-QEVDVVFQENEVMVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQ 963
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
YI ++G ++IL+L+ + H V + F+ T S+ DD + +W
Sbjct: 964 YIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 1019
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 959 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 1017
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 1018 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1075
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1076 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1135
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1136 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1193
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1194 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1235
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 868 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 925
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 926 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 981
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 982 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1037
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1038 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1097
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1098 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1150
>AB209608-1|BAD92845.1| 540|Homo sapiens transducin beta-like 1X
variant protein.
Length = 540
Score = 109 bits (261), Expect = 6e-23
Identities = 77/288 (26%), Positives = 127/288 (44%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N N +AT S D +W G + S Q H + + ++ G Y+ SA
Sbjct: 254 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQ-HKGPIFALKWNRKGNYILSAGV 312
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + ++ + + S D + + + + +F
Sbjct: 313 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-TTFASCSTDMCIHVCRLGCDRPVKTF 371
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G ++ASCSDD + K+W++ CIH DL+ H + W P+
Sbjct: 372 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIH---DLQAHNKEIYTIKWSPT 428
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+DI + H E V VA P G Y+ + S
Sbjct: 429 GPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSF 488
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G+ + + G G + V ++ GD ++ D V +
Sbjct: 489 DKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSVCV 535
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/265 (23%), Positives = 118/265 (44%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T + L L HK I AL +N I ++ +D + ++WD +F H
Sbjct: 276 RIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSA 335
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + ++ + AS S D + + F+ H+ V ++++ G + + S
Sbjct: 336 PALDVDWQNNTTF-ASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCS 394
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + I H + + S N ++AS S D + +LW+
Sbjct: 395 DDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD 454
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
++ G C HT + +A+ P G Y+A + V +++ ++ NLV Y +
Sbjct: 455 IERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYR-GTGGIF 513
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + G + ++ DG + +LDL
Sbjct: 514 EVCWNARGDKVGASASDGSVCVLDL 538
Score = 97.1 bits (231), Expect = 3e-19
Identities = 75/315 (23%), Positives = 136/315 (43%), Gaps = 27/315 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L Q GHD
Sbjct: 191 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 250
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++++G +A+ S D RIW T G+ H + +++++ G+ I+
Sbjct: 251 NKDVTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKWNRKGNYIL 308
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ N+ + ASCS D + L
Sbjct: 309 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-TTFASCSTDMCIHVCRLGCDRP 367
Query: 182 IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+ T++ + W PSG +A + +K++ ++ + HN+ + + P
Sbjct: 368 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSP 427
Query: 242 SGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+G + +AS D +++ D+ G TL+ H PV +V FSP G +S
Sbjct: 428 TGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGS 487
Query: 293 DDKLVFIWKTNFTDL 307
DK V IW T +L
Sbjct: 488 FDKCVHIWNTQSGNL 502
>AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein.
Length = 1237
Score = 109 bits (261), Expect = 6e-23
Identities = 71/302 (23%), Positives = 141/302 (46%), Gaps = 17/302 (5%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 600 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 659
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 660 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 719
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN V R S D ++ASCS D + KLW+ S + I+
Sbjct: 720 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 779
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQVAIH 240
+D++ +W G + VA + + L+DI T L+ + ++ H+ +
Sbjct: 780 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLFDIHTSGLLGEIHTGHHSTIQYCDFS 838
Query: 241 PSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
P + A +++ + + GH V+ V FSP G +F ++ DD+ + +W
Sbjct: 839 PQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLW 898
Query: 301 KT 302
+T
Sbjct: 899 ET 900
Score = 78.6 bits (185), Expect = 1e-13
Identities = 67/296 (22%), Positives = 129/296 (43%), Gaps = 20/296 (6%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRF--------QGHDEA 65
GH N++ ++P+D+ +A+ S D ++ LWD R ++ +F + +
Sbjct: 730 GHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVI 789
Query: 66 VMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTG-MFKAHSQTVRSVQFSSDGSKIITAS 124
V ++S+ G + A+++K + T +G G + H T++ FS + A
Sbjct: 790 VKCCSWSADGARIMVAAKNKIFLFDIHT-SGLLGEIHTGHHSTIQYCDFSPQNHLAVVAL 848
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
V+LW+T ++ GH +WV S DGS + SDD++ +LW C ++
Sbjct: 849 SQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNS 907
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGS 244
LK + + + + V ++L + RT + Y + V+ + P
Sbjct: 908 AVMLK-QEVDVVFQENEVMVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQ 963
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
YI ++G ++IL+L+ + H V + F+ T S+ DD + +W
Sbjct: 964 YIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 1019
Score = 72.5 bits (170), Expect = 6e-12
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 959 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 1017
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 1018 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1075
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1076 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1135
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1136 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1193
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1194 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGIIYILQT 1235
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 868 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 925
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 926 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 981
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 982 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1037
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1038 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1097
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1098 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1150
>EF079890-1|ABN48555.1| 444|Homo sapiens ATG16 autophagy related
16-like protein 1 protein.
Length = 444
Score = 107 bits (257), Expect = 2e-22
Identities = 76/289 (26%), Positives = 127/289 (43%), Gaps = 13/289 (4%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR--FQGHDEAVMDVTFSSSGKY 77
H + A+ ++P + +AT +D V LW++ G ++ G + + + F S+G Y
Sbjct: 158 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 217
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +AS D RIW HS V S +F D ++I++ S D+ +KLW
Sbjct: 218 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 277
Query: 138 KFISS-FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
I + F G + C + + S DK + W++ S E I +L G L
Sbjct: 278 VCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRS-ESIVREMELLGKITALD 332
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH----NEAVTQVAIHPSGSYILTASKD 252
+P + + +K+ D+RT+ + Q +S T+V P GSY+ S +
Sbjct: 333 LNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAE 392
Query: 253 GKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
G + I +L G LS H+ +NAV +SP+G S +W
Sbjct: 393 GSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 441
Score = 91.5 bits (217), Expect = 1e-17
Identities = 65/250 (26%), Positives = 117/250 (46%), Gaps = 14/250 (5%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFS 114
F HD V V FS + +A+ D+ V++W V G FK + + S++F
Sbjct: 155 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLW--EVFGEKCEFKGSLSGSNAGITSIEFD 212
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
S GS ++ AS+D ++W+ ++ + GH+ V A+ D + I S S D++ KLW
Sbjct: 213 SAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 272
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV 234
+L S CI T G + C V ++ +DIR+ ++V+ + + +
Sbjct: 273 DLRSKVCIKTV--FAGSSCNDIVCTEQC-VMSGHFDKKIRFWDIRSESIVREMELLGK-I 328
Query: 235 TQVAIHPSGSYILTASKDGKMKILDLLEG--HPIFTLSGH--NGPVNAVNFSPTGDTFSS 290
T + ++P + +L+ S+D +K++DL F+ G V FSP G ++
Sbjct: 329 TALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAA 388
Query: 291 AGDDKLVFIW 300
+ ++IW
Sbjct: 389 GSAEGSLYIW 398
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/251 (19%), Positives = 99/251 (39%), Gaps = 10/251 (3%)
Query: 10 EPC-LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
E C K L G IT++ ++ + +S D + +W + + GH V+
Sbjct: 191 EKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLS 250
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
F + S S D+T+++W S K +++ DK
Sbjct: 251 AKFLLDNARIVSGSHDRTLKLW---DLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKK 307
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK-- 186
++ W + + + ++ + + + SCS D K+ +L + T+
Sbjct: 308 IRFWDIRSESIVRE-MELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAP 366
Query: 187 --DLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS-IHNEAVTQVAIHPSG 243
+ + P G YVA ++ G++ ++ + T + + S H+ ++ VA PSG
Sbjct: 367 GFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSG 426
Query: 244 SYILTASKDGK 254
S++++ K K
Sbjct: 427 SHVVSVDKGCK 437
Score = 54.0 bits (124), Expect = 2e-06
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST--HKHKFISSFVGHTNWVRCARMSN 157
+F AH V +VQFS + T D+ VKLW K +F S G + +
Sbjct: 154 VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 213
Query: 158 DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYD 217
GS + + S+D ++++W +D HT G L + + + +KL+D
Sbjct: 214 AGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 273
Query: 218 IRT 220
+R+
Sbjct: 274 LRS 276
Score = 46.0 bits (104), Expect = 6e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHD-EAVMD---VTFSSSGKYMA 79
ITAL NP ++ + S D+ + + DLR F + D V FS G Y+A
Sbjct: 328 ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 387
Query: 80 SASRDKTVRIWVPTVTGSTG--MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S + ++ IW +TG + K HS ++ +V +S GS +++ LW+ +
Sbjct: 388 AGSAEGSLYIW-SVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY 444
Score = 32.3 bits (70), Expect = 8.5
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 272 HNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
H+G VNAV FSP ++ G D+ V +W+
Sbjct: 158 HDGEVNAVQFSPGSRLLATGGMDRRVKLWE 187
>EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related
16-like protein 1 protein.
Length = 588
Score = 107 bits (257), Expect = 2e-22
Identities = 76/289 (26%), Positives = 127/289 (43%), Gaps = 13/289 (4%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR--FQGHDEAVMDVTFSSSGKY 77
H + A+ ++P + +AT +D V LW++ G ++ G + + + F S+G Y
Sbjct: 302 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 361
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +AS D RIW HS V S +F D ++I++ S D+ +KLW
Sbjct: 362 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 421
Query: 138 KFISS-FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
I + F G + C + + S DK + W++ S E I +L G L
Sbjct: 422 VCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRS-ESIVREMELLGKITALD 476
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH----NEAVTQVAIHPSGSYILTASKD 252
+P + + +K+ D+RT+ + Q +S T+V P GSY+ S +
Sbjct: 477 LNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAE 536
Query: 253 GKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
G + I +L G LS H+ +NAV +SP+G S +W
Sbjct: 537 GSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 585
Score = 91.5 bits (217), Expect = 1e-17
Identities = 65/250 (26%), Positives = 117/250 (46%), Gaps = 14/250 (5%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFS 114
F HD V V FS + +A+ D+ V++W V G FK + + S++F
Sbjct: 299 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLW--EVFGEKCEFKGSLSGSNAGITSIEFD 356
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
S GS ++ AS+D ++W+ ++ + GH+ V A+ D + I S S D++ KLW
Sbjct: 357 SAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 416
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV 234
+L S CI T G + C V ++ +DIR+ ++V+ + + +
Sbjct: 417 DLRSKVCIKTV--FAGSSCNDIVCTEQC-VMSGHFDKKIRFWDIRSESIVREMELLGK-I 472
Query: 235 TQVAIHPSGSYILTASKDGKMKILDLLEG--HPIFTLSGH--NGPVNAVNFSPTGDTFSS 290
T + ++P + +L+ S+D +K++DL F+ G V FSP G ++
Sbjct: 473 TALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAA 532
Query: 291 AGDDKLVFIW 300
+ ++IW
Sbjct: 533 GSAEGSLYIW 542
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/251 (19%), Positives = 99/251 (39%), Gaps = 10/251 (3%)
Query: 10 EPC-LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
E C K L G IT++ ++ + +S D + +W + + GH V+
Sbjct: 335 EKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLS 394
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
F + S S D+T+++W S K +++ DK
Sbjct: 395 AKFLLDNARIVSGSHDRTLKLW---DLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKK 451
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK-- 186
++ W + + + ++ + + + SCS D K+ +L + T+
Sbjct: 452 IRFWDIRSESIVRE-MELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAP 510
Query: 187 --DLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS-IHNEAVTQVAIHPSG 243
+ + P G YVA ++ G++ ++ + T + + S H+ ++ VA PSG
Sbjct: 511 GFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSG 570
Query: 244 SYILTASKDGK 254
S++++ K K
Sbjct: 571 SHVVSVDKGCK 581
Score = 54.0 bits (124), Expect = 2e-06
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST--HKHKFISSFVGHTNWVRCARMSN 157
+F AH V +VQFS + T D+ VKLW K +F S G + +
Sbjct: 298 VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 357
Query: 158 DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYD 217
GS + + S+D ++++W +D HT G L + + + +KL+D
Sbjct: 358 AGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 417
Query: 218 IRT 220
+R+
Sbjct: 418 LRS 420
Score = 46.0 bits (104), Expect = 6e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHD-EAVMD---VTFSSSGKYMA 79
ITAL NP ++ + S D+ + + DLR F + D V FS G Y+A
Sbjct: 472 ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 531
Query: 80 SASRDKTVRIWVPTVTGSTG--MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S + ++ IW +TG + K HS ++ +V +S GS +++ LW+ +
Sbjct: 532 AGSAEGSLYIW-SVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY 588
Score = 32.3 bits (70), Expect = 8.5
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 272 HNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
H+G VNAV FSP ++ G D+ V +W+
Sbjct: 302 HDGEVNAVQFSPGSRLLATGGMDRRVKLWE 331
>BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein.
Length = 523
Score = 107 bits (257), Expect = 2e-22
Identities = 76/289 (26%), Positives = 127/289 (43%), Gaps = 13/289 (4%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR--FQGHDEAVMDVTFSSSGKY 77
H + A+ ++P + +AT +D V LW++ G ++ G + + + F S+G Y
Sbjct: 237 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 296
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +AS D RIW HS V S +F D ++I++ S D+ +KLW
Sbjct: 297 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 356
Query: 138 KFISS-FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
I + F G + C + + S DK + W++ S E I +L G L
Sbjct: 357 VCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRS-ESIVREMELLGKITALD 411
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH----NEAVTQVAIHPSGSYILTASKD 252
+P + + +K+ D+RT+ + Q +S T+V P GSY+ S +
Sbjct: 412 LNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAE 471
Query: 253 GKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
G + I +L G LS H+ +NAV +SP+G S +W
Sbjct: 472 GSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 520
Score = 91.5 bits (217), Expect = 1e-17
Identities = 65/250 (26%), Positives = 117/250 (46%), Gaps = 14/250 (5%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFS 114
F HD V V FS + +A+ D+ V++W V G FK + + S++F
Sbjct: 234 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLW--EVFGEKCEFKGSLSGSNAGITSIEFD 291
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
S GS ++ AS+D ++W+ ++ + GH+ V A+ D + I S S D++ KLW
Sbjct: 292 SAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 351
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV 234
+L S CI T G + C V ++ +DIR+ ++V+ + + +
Sbjct: 352 DLRSKVCIKTV--FAGSSCNDIVCTEQC-VMSGHFDKKIRFWDIRSESIVREMELLGK-I 407
Query: 235 TQVAIHPSGSYILTASKDGKMKILDLLEG--HPIFTLSGH--NGPVNAVNFSPTGDTFSS 290
T + ++P + +L+ S+D +K++DL F+ G V FSP G ++
Sbjct: 408 TALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAA 467
Query: 291 AGDDKLVFIW 300
+ ++IW
Sbjct: 468 GSAEGSLYIW 477
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/251 (19%), Positives = 99/251 (39%), Gaps = 10/251 (3%)
Query: 10 EPC-LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
E C K L G IT++ ++ + +S D + +W + + GH V+
Sbjct: 270 EKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLS 329
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
F + S S D+T+++W S K +++ DK
Sbjct: 330 AKFLLDNARIVSGSHDRTLKLW---DLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKK 386
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK-- 186
++ W + + + ++ + + + SCS D K+ +L + T+
Sbjct: 387 IRFWDIRSESIVRE-MELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAP 445
Query: 187 --DLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS-IHNEAVTQVAIHPSG 243
+ + P G YVA ++ G++ ++ + T + + S H+ ++ VA PSG
Sbjct: 446 GFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSG 505
Query: 244 SYILTASKDGK 254
S++++ K K
Sbjct: 506 SHVVSVDKGCK 516
Score = 54.0 bits (124), Expect = 2e-06
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST--HKHKFISSFVGHTNWVRCARMSN 157
+F AH V +VQFS + T D+ VKLW K +F S G + +
Sbjct: 233 VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 292
Query: 158 DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYD 217
GS + + S+D ++++W +D HT G L + + + +KL+D
Sbjct: 293 AGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 352
Query: 218 IRT 220
+R+
Sbjct: 353 LRS 355
Score = 46.0 bits (104), Expect = 6e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHD-EAVMD---VTFSSSGKYMA 79
ITAL NP ++ + S D+ + + DLR F + D V FS G Y+A
Sbjct: 407 ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 466
Query: 80 SASRDKTVRIWVPTVTGSTG--MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S + ++ IW +TG + K HS ++ +V +S GS +++ LW+ +
Sbjct: 467 AGSAEGSLYIW-SVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY 523
Score = 32.3 bits (70), Expect = 8.5
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 272 HNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
H+G VNAV FSP ++ G D+ V +W+
Sbjct: 237 HDGEVNAVQFSPGSRLLATGGMDRRVKLWE 266
>BC071846-1|AAH71846.1| 475|Homo sapiens ATG16L1 protein protein.
Length = 475
Score = 107 bits (257), Expect = 2e-22
Identities = 76/289 (26%), Positives = 127/289 (43%), Gaps = 13/289 (4%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR--FQGHDEAVMDVTFSSSGKY 77
H + A+ ++P + +AT +D V LW++ G ++ G + + + F S+G Y
Sbjct: 189 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 248
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +AS D RIW HS V S +F D ++I++ S D+ +KLW
Sbjct: 249 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 308
Query: 138 KFISS-FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
I + F G + C + + S DK + W++ S E I +L G L
Sbjct: 309 VCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRS-ESIVREMELLGKITALD 363
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH----NEAVTQVAIHPSGSYILTASKD 252
+P + + +K+ D+RT+ + Q +S T+V P GSY+ S +
Sbjct: 364 LNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAE 423
Query: 253 GKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
G + I +L G LS H+ +NAV +SP+G S +W
Sbjct: 424 GSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 472
Score = 91.5 bits (217), Expect = 1e-17
Identities = 65/250 (26%), Positives = 117/250 (46%), Gaps = 14/250 (5%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFS 114
F HD V V FS + +A+ D+ V++W V G FK + + S++F
Sbjct: 186 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLW--EVFGEKCEFKGSLSGSNAGITSIEFD 243
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
S GS ++ AS+D ++W+ ++ + GH+ V A+ D + I S S D++ KLW
Sbjct: 244 SAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 303
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV 234
+L S CI T G + C V ++ +DIR+ ++V+ + + +
Sbjct: 304 DLRSKVCIKTV--FAGSSCNDIVCTEQC-VMSGHFDKKIRFWDIRSESIVREMELLGK-I 359
Query: 235 TQVAIHPSGSYILTASKDGKMKILDLLEG--HPIFTLSGH--NGPVNAVNFSPTGDTFSS 290
T + ++P + +L+ S+D +K++DL F+ G V FSP G ++
Sbjct: 360 TALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAA 419
Query: 291 AGDDKLVFIW 300
+ ++IW
Sbjct: 420 GSAEGSLYIW 429
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/251 (19%), Positives = 99/251 (39%), Gaps = 10/251 (3%)
Query: 10 EPC-LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
E C K L G IT++ ++ + +S D + +W + + GH V+
Sbjct: 222 EKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLS 281
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
F + S S D+T+++W S K +++ DK
Sbjct: 282 AKFLLDNARIVSGSHDRTLKLW---DLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKK 338
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK-- 186
++ W + + + ++ + + + SCS D K+ +L + T+
Sbjct: 339 IRFWDIRSESIVRE-MELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAP 397
Query: 187 --DLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS-IHNEAVTQVAIHPSG 243
+ + P G YVA ++ G++ ++ + T + + S H+ ++ VA PSG
Sbjct: 398 GFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSG 457
Query: 244 SYILTASKDGK 254
S++++ K K
Sbjct: 458 SHVVSVDKGCK 468
Score = 54.0 bits (124), Expect = 2e-06
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST--HKHKFISSFVGHTNWVRCARMSN 157
+F AH V +VQFS + T D+ VKLW K +F S G + +
Sbjct: 185 VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 244
Query: 158 DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYD 217
GS + + S+D ++++W +D HT G L + + + +KL+D
Sbjct: 245 AGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 304
Query: 218 IRT 220
+R+
Sbjct: 305 LRS 307
Score = 46.0 bits (104), Expect = 6e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHD-EAVMD---VTFSSSGKYMA 79
ITAL NP ++ + S D+ + + DLR F + D V FS G Y+A
Sbjct: 359 ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 418
Query: 80 SASRDKTVRIWVPTVTGSTG--MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S + ++ IW +TG + K HS ++ +V +S GS +++ LW+ +
Sbjct: 419 AGSAEGSLYIW-SVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY 475
Score = 32.3 bits (70), Expect = 8.5
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 272 HNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
H+G VNAV FSP ++ G D+ V +W+
Sbjct: 189 HDGEVNAVQFSPGSRLLATGGMDRRVKLWE 218
>AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein.
Length = 607
Score = 107 bits (257), Expect = 2e-22
Identities = 76/289 (26%), Positives = 127/289 (43%), Gaps = 13/289 (4%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR--FQGHDEAVMDVTFSSSGKY 77
H + A+ ++P + +AT +D V LW++ G ++ G + + + F S+G Y
Sbjct: 321 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 380
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +AS D RIW HS V S +F D ++I++ S D+ +KLW
Sbjct: 381 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 440
Query: 138 KFISS-FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
I + F G + C + + S DK + W++ S E I +L G L
Sbjct: 441 VCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRS-ESIVREMELLGKITALD 495
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH----NEAVTQVAIHPSGSYILTASKD 252
+P + + +K+ D+RT+ + Q +S T+V P GSY+ S +
Sbjct: 496 LNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAE 555
Query: 253 GKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
G + I +L G LS H+ +NAV +SP+G S +W
Sbjct: 556 GSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 604
Score = 91.5 bits (217), Expect = 1e-17
Identities = 65/250 (26%), Positives = 117/250 (46%), Gaps = 14/250 (5%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFS 114
F HD V V FS + +A+ D+ V++W V G FK + + S++F
Sbjct: 318 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLW--EVFGEKCEFKGSLSGSNAGITSIEFD 375
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
S GS ++ AS+D ++W+ ++ + GH+ V A+ D + I S S D++ KLW
Sbjct: 376 SAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 435
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV 234
+L S CI T G + C V ++ +DIR+ ++V+ + + +
Sbjct: 436 DLRSKVCIKTV--FAGSSCNDIVCTEQC-VMSGHFDKKIRFWDIRSESIVREMELLGK-I 491
Query: 235 TQVAIHPSGSYILTASKDGKMKILDLLEG--HPIFTLSGH--NGPVNAVNFSPTGDTFSS 290
T + ++P + +L+ S+D +K++DL F+ G V FSP G ++
Sbjct: 492 TALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAA 551
Query: 291 AGDDKLVFIW 300
+ ++IW
Sbjct: 552 GSAEGSLYIW 561
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/251 (19%), Positives = 99/251 (39%), Gaps = 10/251 (3%)
Query: 10 EPC-LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
E C K L G IT++ ++ + +S D + +W + + GH V+
Sbjct: 354 EKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLS 413
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
F + S S D+T+++W S K +++ DK
Sbjct: 414 AKFLLDNARIVSGSHDRTLKLW---DLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKK 470
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK-- 186
++ W + + + ++ + + + SCS D K+ +L + T+
Sbjct: 471 IRFWDIRSESIVRE-MELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAP 529
Query: 187 --DLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS-IHNEAVTQVAIHPSG 243
+ + P G YVA ++ G++ ++ + T + + S H+ ++ VA PSG
Sbjct: 530 GFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSG 589
Query: 244 SYILTASKDGK 254
S++++ K K
Sbjct: 590 SHVVSVDKGCK 600
Score = 54.0 bits (124), Expect = 2e-06
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST--HKHKFISSFVGHTNWVRCARMSN 157
+F AH V +VQFS + T D+ VKLW K +F S G + +
Sbjct: 317 VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 376
Query: 158 DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYD 217
GS + + S+D ++++W +D HT G L + + + +KL+D
Sbjct: 377 AGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 436
Query: 218 IRT 220
+R+
Sbjct: 437 LRS 439
Score = 46.0 bits (104), Expect = 6e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHD-EAVMD---VTFSSSGKYMA 79
ITAL NP ++ + S D+ + + DLR F + D V FS G Y+A
Sbjct: 491 ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 550
Query: 80 SASRDKTVRIWVPTVTGSTG--MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S + ++ IW +TG + K HS ++ +V +S GS +++ LW+ +
Sbjct: 551 AGSAEGSLYIW-SVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY 607
Score = 32.3 bits (70), Expect = 8.5
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 272 HNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
H+G VNAV FSP ++ G D+ V +W+
Sbjct: 321 HDGEVNAVQFSPGSRLLATGGMDRRVKLWE 350
>AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein.
Length = 523
Score = 107 bits (257), Expect = 2e-22
Identities = 76/289 (26%), Positives = 127/289 (43%), Gaps = 13/289 (4%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR--FQGHDEAVMDVTFSSSGKY 77
H + A+ ++P + +AT +D V LW++ G ++ G + + + F S+G Y
Sbjct: 237 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 296
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +AS D RIW HS V S +F D ++I++ S D+ +KLW
Sbjct: 297 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 356
Query: 138 KFISS-FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
I + F G + C + + S DK + W++ S E I +L G L
Sbjct: 357 VCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRS-ESIVREMELLGKITALD 411
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH----NEAVTQVAIHPSGSYILTASKD 252
+P + + +K+ D+RT+ + Q +S T+V P GSY+ S +
Sbjct: 412 LNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAE 471
Query: 253 GKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
G + I +L G LS H+ +NAV +SP+G S +W
Sbjct: 472 GSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 520
Score = 91.5 bits (217), Expect = 1e-17
Identities = 65/250 (26%), Positives = 117/250 (46%), Gaps = 14/250 (5%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFS 114
F HD V V FS + +A+ D+ V++W V G FK + + S++F
Sbjct: 234 FDAHDGEVNAVQFSPGSRLLATGGMDRRVKLW--EVFGEKCEFKGSLSGSNAGITSIEFD 291
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
S GS ++ AS+D ++W+ ++ + GH+ V A+ D + I S S D++ KLW
Sbjct: 292 SAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 351
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV 234
+L S CI T G + C V ++ +DIR+ ++V+ + + +
Sbjct: 352 DLRSKVCIKTV--FAGSSCNDIVCTEQC-VMSGHFDKKIRFWDIRSESIVREMELLGK-I 407
Query: 235 TQVAIHPSGSYILTASKDGKMKILDLLEG--HPIFTLSGH--NGPVNAVNFSPTGDTFSS 290
T + ++P + +L+ S+D +K++DL F+ G V FSP G ++
Sbjct: 408 TALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAA 467
Query: 291 AGDDKLVFIW 300
+ ++IW
Sbjct: 468 GSAEGSLYIW 477
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/251 (19%), Positives = 99/251 (39%), Gaps = 10/251 (3%)
Query: 10 EPC-LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
E C K L G IT++ ++ + +S D + +W + + GH V+
Sbjct: 270 EKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLS 329
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
F + S S D+T+++W S K +++ DK
Sbjct: 330 AKFLLDNARIVSGSHDRTLKLW---DLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKK 386
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK-- 186
++ W + + + ++ + + + SCS D K+ +L + T+
Sbjct: 387 IRFWDIRSESIVRE-MELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAP 445
Query: 187 --DLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS-IHNEAVTQVAIHPSG 243
+ + P G YVA ++ G++ ++ + T + + S H+ ++ VA PSG
Sbjct: 446 GFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSG 505
Query: 244 SYILTASKDGK 254
S++++ K K
Sbjct: 506 SHVVSVDKGCK 516
Score = 54.0 bits (124), Expect = 2e-06
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST--HKHKFISSFVGHTNWVRCARMSN 157
+F AH V +VQFS + T D+ VKLW K +F S G + +
Sbjct: 233 VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 292
Query: 158 DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYD 217
GS + + S+D ++++W +D HT G L + + + +KL+D
Sbjct: 293 AGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 352
Query: 218 IRT 220
+R+
Sbjct: 353 LRS 355
Score = 46.0 bits (104), Expect = 6e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHD-EAVMD---VTFSSSGKYMA 79
ITAL NP ++ + S D+ + + DLR F + D V FS G Y+A
Sbjct: 407 ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 466
Query: 80 SASRDKTVRIWVPTVTGSTG--MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S + ++ IW +TG + K HS ++ +V +S GS +++ LW+ +
Sbjct: 467 AGSAEGSLYIW-SVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY 523
Score = 32.3 bits (70), Expect = 8.5
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 272 HNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
H+G VNAV FSP ++ G D+ V +W+
Sbjct: 237 HDGEVNAVQFSPGSRLLATGGMDRRVKLWE 266
>AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens
cDNA FLJ45988 fis, clone PUAEN2006639, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 369
Score = 106 bits (255), Expect = 3e-22
Identities = 63/236 (26%), Positives = 109/236 (46%), Gaps = 1/236 (0%)
Query: 60 QGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSD-GS 118
+ H + +V + SG + S D+T ++W + H V ++ F++ G
Sbjct: 89 KAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGD 148
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
KI T S DK KLWS K +F GHT + C + +++A+ S D + KLW++ +
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQN 208
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
GE ++T + + L+++ SG + + V ++D T V H ++ +
Sbjct: 209 GEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSAS 268
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDD 294
+ S ILT S D K+ D G + TL+GH+ + F TG ++A D
Sbjct: 269 FNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASAD 324
Score = 105 bits (251), Expect = 1e-21
Identities = 56/200 (28%), Positives = 100/200 (50%), Gaps = 1/200 (0%)
Query: 17 LKGHKNAITALYYN-PNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
L+GH+N + A+ +N P +IAT S D + LW + + F+GH ++ ++F+
Sbjct: 130 LEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQS 189
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+A+ S D T ++W + HS + S+ F++ G +IIT S D V +W
Sbjct: 190 TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDAD 249
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL 195
+ ++ +GH + A + D S+I + S DK+ KLW+ +G+C+ T L
Sbjct: 250 TGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDS 309
Query: 196 AWHPSGCYVAVATSHGNVKL 215
+ +G +A A++ V L
Sbjct: 310 CFDYTGKLIATASADDGVSL 329
Score = 99.1 bits (236), Expect = 7e-20
Identities = 56/202 (27%), Positives = 99/202 (49%), Gaps = 1/202 (0%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSND- 158
+ KAH + +V + GS IT S D+ KLW + + +++ GH N V +N
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPY 146
Query: 159 GSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI 218
G IA+ S DK+ KLW++++G+C HT++ + L+++P VA + KL+DI
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 219 RTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNA 278
+ V H+ + ++ + SG I+T S D + + D G + L GH +++
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISS 266
Query: 279 VNFSPTGDTFSSAGDDKLVFIW 300
+F+ + DK +W
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLW 288
Score = 78.2 bits (184), Expect = 1e-13
Identities = 56/244 (22%), Positives = 100/244 (40%), Gaps = 7/244 (2%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L K LK H +T + N + T S D + LWD +GH V + F+
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFN 143
Query: 73 SS-GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+ G +A+ S DKT ++W F+ H+ + + F+ + + T S D KL
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + + GH+ + + G I + S D + +W+ D+G ++ L GH
Sbjct: 204 WDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNI---LIGH 260
Query: 192 GLHL---AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILT 248
+ +++ + + KL+D V + H++ + +G I T
Sbjct: 261 CAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIAT 320
Query: 249 ASKD 252
AS D
Sbjct: 321 ASAD 324
Score = 49.6 bits (113), Expect = 5e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
T L + H +T VA++ SGS +T S D K+ D G + TL GH V A+
Sbjct: 81 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAI 140
Query: 280 NF-SPTGDTFSSAGDDKLVFIW 300
F +P GD ++ DK +W
Sbjct: 141 AFNNPYGDKIATGSFDKTCKLW 162
Score = 46.4 bits (105), Expect = 5e-04
Identities = 25/76 (32%), Positives = 38/76 (50%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH I++ +N + I T S+D + LWD GHD+ ++D F +GK
Sbjct: 257 LIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGK 316
Query: 77 YMASASRDKTVRIWVP 92
+A+AS D V + P
Sbjct: 317 LIATASADDGVSLCRP 332
>AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens
cDNA FLJ14948 fis, clone PLACE2000164, weakly similar to
TIPD PROTEIN. ).
Length = 504
Score = 106 bits (255), Expect = 3e-22
Identities = 76/289 (26%), Positives = 126/289 (43%), Gaps = 13/289 (4%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR--FQGHDEAVMDVTFSSSGKY 77
H + A ++P + +AT +D V LW++ G ++ G + + + F S+G Y
Sbjct: 218 HDGEVNAAQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 277
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +AS D RIW HS V S +F D ++I++ S D+ +KLW
Sbjct: 278 LLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 337
Query: 138 KFISS-FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
I + F G + C + + S DK + W++ S E I +L G L
Sbjct: 338 VCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRS-ESIVREMELLGKITALD 392
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIH----NEAVTQVAIHPSGSYILTASKD 252
+P + + +K+ D+RT+ + Q +S T+V P GSY+ S +
Sbjct: 393 LNPERTELLSCSRDDLLKVIDLRTNAIKQTFSATGFKCGSDWTRVVFSPDGSYVAAGSAE 452
Query: 253 GKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
G + I +L G LS H+ +NAV +SP+G S +W
Sbjct: 453 GSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 501
Score = 90.6 bits (215), Expect = 2e-17
Identities = 64/250 (25%), Positives = 117/250 (46%), Gaps = 14/250 (5%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFS 114
F HD V FS + +A+ D+ V++W V G FK + + S++F
Sbjct: 215 FDAHDGEVNAAQFSPGSRLLATGGMDRRVKLW--EVFGEKCEFKGSLSGSNAGITSIEFD 272
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
S GS ++ AS+D ++W+ ++ + GH+ V A+ D + I S S D++ KLW
Sbjct: 273 SAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 332
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV 234
+L S CI T G + C V ++ +DIR+ ++V+ + + +
Sbjct: 333 DLRSKVCIKTV--FAGSSCNDIVCTEQC-VMSGHFDKKIRFWDIRSESIVREMELLGK-I 388
Query: 235 TQVAIHPSGSYILTASKDGKMKILDLLEG--HPIFTLSGH--NGPVNAVNFSPTGDTFSS 290
T + ++P + +L+ S+D +K++DL F+ +G V FSP G ++
Sbjct: 389 TALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSATGFKCGSDWTRVVFSPDGSYVAA 448
Query: 291 AGDDKLVFIW 300
+ ++IW
Sbjct: 449 GSAEGSLYIW 458
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/251 (19%), Positives = 99/251 (39%), Gaps = 10/251 (3%)
Query: 10 EPC-LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
E C K L G IT++ ++ + +S D + +W + + GH V+
Sbjct: 251 EKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLS 310
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
F + S S D+T+++W S K +++ DK
Sbjct: 311 AKFLLDNARIVSGSHDRTLKLW---DLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKK 367
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK-- 186
++ W + + + ++ + + + SCS D K+ +L + T+
Sbjct: 368 IRFWDIRSESIVRE-MELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAT 426
Query: 187 --DLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS-IHNEAVTQVAIHPSG 243
+ + P G YVA ++ G++ ++ + T + + S H+ ++ VA PSG
Sbjct: 427 GFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSG 486
Query: 244 SYILTASKDGK 254
S++++ K K
Sbjct: 487 SHVVSVDKGCK 497
Score = 52.4 bits (120), Expect = 7e-06
Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 2/123 (1%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST--HKHKFISSFVGHTNWVRCARMSN 157
+F AH V + QFS + T D+ VKLW K +F S G + +
Sbjct: 214 VFDAHDGEVNAAQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 273
Query: 158 DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYD 217
GS + + S+D ++++W +D HT G L + + + +KL+D
Sbjct: 274 AGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 333
Query: 218 IRT 220
+R+
Sbjct: 334 LRS 336
Score = 46.0 bits (104), Expect = 6e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHD-EAVMD---VTFSSSGKYMA 79
ITAL NP ++ + S D+ + + DLR F + D V FS G Y+A
Sbjct: 388 ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSATGFKCGSDWTRVVFSPDGSYVA 447
Query: 80 SASRDKTVRIWVPTVTGSTG--MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S + ++ IW +TG + K HS ++ +V +S GS +++ LW+ +
Sbjct: 448 AGSAEGSLYIW-SVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY 504
>AL117629-1|CAB56021.1| 192|Homo sapiens hypothetical protein
protein.
Length = 192
Score = 106 bits (254), Expect = 4e-22
Identities = 43/84 (51%), Positives = 61/84 (72%)
Query: 221 HNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
H L+Q+Y +H+ AV ++ HPSG+Y++TAS D +KILDL+EG ++TL GH GP V
Sbjct: 4 HRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVA 63
Query: 281 FSPTGDTFSSAGDDKLVFIWKTNF 304
FS TG+ F+S G D+ V +WK+NF
Sbjct: 64 FSRTGEYFASGGSDEQVMVWKSNF 87
Score = 50.0 bits (114), Expect = 4e-05
Identities = 22/71 (30%), Positives = 36/71 (50%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMA 79
H A+ L ++P+ + T+S D+++ + DL Y GH V FS +G+Y A
Sbjct: 13 HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 72
Query: 80 SASRDKTVRIW 90
S D+ V +W
Sbjct: 73 SGGSDEQVMVW 83
Score = 41.1 bits (92), Expect = 0.018
Identities = 19/74 (25%), Positives = 32/74 (43%)
Query: 101 FKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS 160
++ HS V + F G+ +ITAS D +K+ + + + + GH S G
Sbjct: 10 YQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGE 69
Query: 161 IIASCSDDKSTKLW 174
AS D+ +W
Sbjct: 70 YFASGGSDEQVMVW 83
Score = 38.3 bits (85), Expect = 0.13
Identities = 21/77 (27%), Positives = 34/77 (44%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
+Q H AV ++F SG Y+ +AS D T++I H +V FS G
Sbjct: 10 YQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGE 69
Query: 119 KIITASDDKVVKLWSTH 135
+ D+ V +W ++
Sbjct: 70 YFASGGSDEQVMVWKSN 86
>AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor
protein.
Length = 310
Score = 106 bits (254), Expect = 4e-22
Identities = 63/252 (25%), Positives = 124/252 (49%), Gaps = 11/252 (4%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
GH+ V F +G +ASA D+ + +W V + K HS V + +++DGS
Sbjct: 5 GHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSM 64
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVR-CARMSNDGSIIASCSDDKSTKLWNLDS 178
+ +AS DK V +W + + + GHT++V C ++ + SDD + KLW++
Sbjct: 65 LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRK 124
Query: 179 GECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
+ T+++ L + ++ + + ++K++D+R + L H ++VT ++
Sbjct: 125 KAAVQTFQNTY-QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 183
Query: 239 IHPSGSYILTASKDGKMKILDLLEGHP------IFTLSGHNGPVNAV--NFSPTGDTFSS 290
+ GSY+L+ + D +++ D+ P IF + HN N + ++SP G ++
Sbjct: 184 LSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAA 243
Query: 291 AGDDKLVFIWKT 302
D+ V++W T
Sbjct: 244 GSADRFVYVWDT 255
Score = 99 bits (238), Expect = 4e-20
Identities = 66/253 (26%), Positives = 116/253 (45%), Gaps = 11/253 (4%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR-FQGHDEAVMDVTFSSSG 75
L GH+ + ++PN +A++ D +LLW++ G +Y +GH AVM++ +++ G
Sbjct: 3 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 62
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII-TASDDKVVKLWST 134
+ SAS DKTV +W K H+ V S + G +++ T SDD VKLW
Sbjct: 63 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 122
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
K + +F +T V ++ I S D K+W+L + +T +
Sbjct: 123 RKKAAVQTF-QNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTG 181
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIR----THNLVQYY--SIHN--EAVTQVAIHPSGSYI 246
L+ G Y+ V+++D+R V+ + ++HN + + + + P GS I
Sbjct: 182 LSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKI 241
Query: 247 LTASKDGKMKILD 259
S D + + D
Sbjct: 242 AAGSADRFVYVWD 254
Score = 82.6 bits (195), Expect = 6e-15
Identities = 55/206 (26%), Positives = 97/206 (47%), Gaps = 9/206 (4%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH-KFISSFVGHTNWVRCARMSND 158
+ H V +F +GS + +A D+++ LW+ + ++ GH+ V + D
Sbjct: 2 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTD 61
Query: 159 GSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPS---GCYVAVATSHGNVK 214
GS++ S S DK+ +W+ ++GE + K LKGH + + +P+ V + G VK
Sbjct: 62 GSMLFSASTDKTVAVWDSETGERV---KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVK 118
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
L+DIR VQ + + V V + + I++ D +K+ DL + +T+ GH
Sbjct: 119 LWDIRKKAAVQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD 177
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ S G S D V +W
Sbjct: 178 SVTGLSLSSEGSYLLSNAMDNTVRVW 203
Score = 76.2 bits (179), Expect = 5e-13
Identities = 50/174 (28%), Positives = 85/174 (48%), Gaps = 12/174 (6%)
Query: 15 KQLKGHKNAITALY-YNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
K+LKGH + + + Y Q + T S D +V LWD+R FQ + V+ VTF+
Sbjct: 86 KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQNTYQ-VLAVTFND 144
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ + S D +++W T + H+ +V + SS+GS +++ + D V++W
Sbjct: 145 TSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 204
Query: 134 TH----KHKFISSFVGHT-----NWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
K + + F G+ N +RC+ S DGS IA+ S D+ +W+ S
Sbjct: 205 VRPFAPKERCVKIFQGNVHNFEKNLLRCS-WSPDGSKIAAGSADRFVYVWDTTS 257
Score = 71.7 bits (168), Expect = 1e-11
Identities = 39/127 (30%), Positives = 62/127 (48%), Gaps = 8/127 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+ A+ +N QI + +DN + +WDLR +Y +GH ++V ++ SS G Y+ S +
Sbjct: 137 VLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAM 196
Query: 84 DKTVRIW-VPTVTGSTGMFKAHSQTVRSVQ-------FSSDGSKIITASDDKVVKLWSTH 135
D TVR+W V K V + + +S DGSKI S D+ V +W T
Sbjct: 197 DNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTT 256
Query: 136 KHKFISS 142
+ +S
Sbjct: 257 SRRSCTS 263
>AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 105 bits (253), Expect = 6e-22
Identities = 70/302 (23%), Positives = 140/302 (46%), Gaps = 17/302 (5%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 670
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN V R S D ++ASCS D + KLW+ S + I+
Sbjct: 731 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 790
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQVAIH 240
+D++ +W G + VA + + L+ I T L+ + ++ H+ +
Sbjct: 791 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLFAIHTSGLLGEIHTGHHSTIQYCDFS 849
Query: 241 PSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
P + A +++ + + GH V+ V FSP G +F ++ DD+ + +W
Sbjct: 850 PQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLW 909
Query: 301 KT 302
+T
Sbjct: 910 ET 911
Score = 79.0 bits (186), Expect = 7e-14
Identities = 67/296 (22%), Positives = 129/296 (43%), Gaps = 20/296 (6%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRF--------QGHDEA 65
GH N++ ++P+D+ +A+ S D ++ LWD R ++ +F + +
Sbjct: 741 GHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVI 800
Query: 66 VMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTG-MFKAHSQTVRSVQFSSDGSKIITAS 124
V ++S+ G + A+++K + T +G G + H T++ FS + A
Sbjct: 801 VKCCSWSADGARIMVAAKNKIFLFAIHT-SGLLGEIHTGHHSTIQYCDFSPQNHLAVVAL 859
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
V+LW+T ++ GH +WV S DGS + SDD++ +LW C ++
Sbjct: 860 SQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNS 918
Query: 185 YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGS 244
LK + + + + V ++L + RT + Y + V+ + P
Sbjct: 919 AVMLK-QEVDVVFQENEVMVLAVDHIRRLQLVNGRT-GQIDY--LTEAQVSCCCLSPHLQ 974
Query: 245 YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
YI ++G ++IL+L+ + H V + F+ T S+ DD + +W
Sbjct: 975 YIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 1030
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 970 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 1028
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 1029 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1086
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1087 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1146
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1147 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1204
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1205 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1246
Score = 64.1 bits (149), Expect = 2e-09
Identities = 66/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 879 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 936
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ V G TG ++ S S + I D+ +++
Sbjct: 937 VLAVDHIRRLQL----VNGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 992
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 993 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1048
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1049 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1108
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1109 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1161
>M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transducin
beta-2 subunit mRNA, complete cds. ).
Length = 340
Score = 105 bits (252), Expect = 8e-22
Identities = 70/293 (23%), Positives = 130/293 (44%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + T G+ + + H+ + +F D ++IIT+S D
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + F GH+ V ++ DG S + D S KLW++ C T+ +
Sbjct: 167 ALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+A+ P+G + +L+D+R + YS N +T VA SG +L
Sbjct: 227 SDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D I D ++G L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 83.8 bits (198), Expect = 3e-15
Identities = 60/254 (23%), Positives = 105/254 (41%), Gaps = 8/254 (3%)
Query: 54 MRSYR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
MR+ R +GH + + + + + + SAS+D + IW T S V +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA 104
Query: 113 FSSDGSKIITASDDKVVKLWSTHKH----KFISSFVGHTNWVRCARMSNDGSIIASCSDD 168
++ G+ + D + ++S + GHT ++ C R +D II S S D
Sbjct: 105 YAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGD 163
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS 228
+ LW++++G+ + G + L+ P G ++KL+D+R Q +
Sbjct: 164 TTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFI 223
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN--GPVNAVNFSPTGD 286
H + VA P+G T S D ++ DL + S N + +V FS +G
Sbjct: 224 GHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 287 TFSSAGDDKLVFIW 300
+ DD IW
Sbjct: 284 LLLAGYDDFNCNIW 297
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S+ LWD+R +M F GH+ + V F +G
Sbjct: 182 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S D T R++ M+ +H + SV FS G ++ DD +W
Sbjct: 242 TTGSDDATCRLFDLRADQELLMY-SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 105 bits (252), Expect = 8e-22
Identities = 70/293 (23%), Positives = 130/293 (44%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + T G+ + + H+ + +F D ++IIT+S D
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + F GH+ V ++ DG S + D S KLW++ C T+ +
Sbjct: 167 ALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+A+ P+G + +L+D+R + YS N +T VA SG +L
Sbjct: 227 SDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D I D ++G L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 83.8 bits (198), Expect = 3e-15
Identities = 60/254 (23%), Positives = 105/254 (41%), Gaps = 8/254 (3%)
Query: 54 MRSYR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
MR+ R +GH + + + + + + SAS+D + IW T S V +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA 104
Query: 113 FSSDGSKIITASDDKVVKLWSTHKH----KFISSFVGHTNWVRCARMSNDGSIIASCSDD 168
++ G+ + D + ++S + GHT ++ C R +D II S S D
Sbjct: 105 YAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGD 163
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS 228
+ LW++++G+ + G + L+ P G ++KL+D+R Q +
Sbjct: 164 TTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFI 223
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN--GPVNAVNFSPTGD 286
H + VA P+G T S D ++ DL + S N + +V FS +G
Sbjct: 224 GHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 287 TFSSAGDDKLVFIW 300
+ DD IW
Sbjct: 284 LLLAGYDDFNCNIW 297
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S+ LWD+R +M F GH+ + V F +G
Sbjct: 182 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S D T R++ M+ +H + SV FS G ++ DD +W
Sbjct: 242 TTGSDDATCRLFDLRADQELLMY-SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 105 bits (252), Expect = 8e-22
Identities = 70/293 (23%), Positives = 130/293 (44%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + T G+ + + H+ + +F D ++IIT+S D
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + F GH+ V ++ DG S + D S KLW++ C T+ +
Sbjct: 167 ALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+A+ P+G + +L+D+R + YS N +T VA SG +L
Sbjct: 227 SDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D I D ++G L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 83.8 bits (198), Expect = 3e-15
Identities = 60/254 (23%), Positives = 105/254 (41%), Gaps = 8/254 (3%)
Query: 54 MRSYR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
MR+ R +GH + + + + + + SAS+D + IW T S V +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA 104
Query: 113 FSSDGSKIITASDDKVVKLWSTHKH----KFISSFVGHTNWVRCARMSNDGSIIASCSDD 168
++ G+ + D + ++S + GHT ++ C R +D II S S D
Sbjct: 105 YAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGD 163
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS 228
+ LW++++G+ + G + L+ P G ++KL+D+R Q +
Sbjct: 164 TTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFI 223
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN--GPVNAVNFSPTGD 286
H + VA P+G T S D ++ DL + S N + +V FS +G
Sbjct: 224 GHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 287 TFSSAGDDKLVFIW 300
+ DD IW
Sbjct: 284 LLLAGYDDFNCNIW 297
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S+ LWD+R +M F GH+ + V F +G
Sbjct: 182 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S D T R++ M+ +H + SV FS G ++ DD +W
Sbjct: 242 TTGSDDATCRLFDLRADQELLMY-SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 105 bits (252), Expect = 8e-22
Identities = 70/293 (23%), Positives = 130/293 (44%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + T G+ + + H+ + +F D ++IIT+S D
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + F GH+ V ++ DG S + D S KLW++ C T+ +
Sbjct: 167 ALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+A+ P+G + +L+D+R + YS N +T VA SG +L
Sbjct: 227 SDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D I D ++G L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 83.8 bits (198), Expect = 3e-15
Identities = 60/254 (23%), Positives = 105/254 (41%), Gaps = 8/254 (3%)
Query: 54 MRSYR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
MR+ R +GH + + + + + + SAS+D + IW T S V +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA 104
Query: 113 FSSDGSKIITASDDKVVKLWSTHKH----KFISSFVGHTNWVRCARMSNDGSIIASCSDD 168
++ G+ + D + ++S + GHT ++ C R +D II S S D
Sbjct: 105 YAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGD 163
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS 228
+ LW++++G+ + G + L+ P G ++KL+D+R Q +
Sbjct: 164 TTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFI 223
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN--GPVNAVNFSPTGD 286
H + VA P+G T S D ++ DL + S N + +V FS +G
Sbjct: 224 GHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 287 TFSSAGDDKLVFIW 300
+ DD IW
Sbjct: 284 LLLAGYDDFNCNIW 297
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S+ LWD+R +M F GH+ + V F +G
Sbjct: 182 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S D T R++ M+ +H + SV FS G ++ DD +W
Sbjct: 242 TTGSDDATCRLFDLRADQELLMY-SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 105 bits (252), Expect = 8e-22
Identities = 70/293 (23%), Positives = 130/293 (44%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + T G+ + + H+ + +F D ++IIT+S D
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + F GH+ V ++ DG S + D S KLW++ C T+ +
Sbjct: 167 ALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+A+ P+G + +L+D+R + YS N +T VA SG +L
Sbjct: 227 SDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D I D ++G L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 83.8 bits (198), Expect = 3e-15
Identities = 60/254 (23%), Positives = 105/254 (41%), Gaps = 8/254 (3%)
Query: 54 MRSYR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
MR+ R +GH + + + + + + SAS+D + IW T S V +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA 104
Query: 113 FSSDGSKIITASDDKVVKLWSTHKH----KFISSFVGHTNWVRCARMSNDGSIIASCSDD 168
++ G+ + D + ++S + GHT ++ C R +D II S S D
Sbjct: 105 YAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGD 163
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS 228
+ LW++++G+ + G + L+ P G ++KL+D+R Q +
Sbjct: 164 TTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFI 223
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN--GPVNAVNFSPTGD 286
H + VA P+G T S D ++ DL + S N + +V FS +G
Sbjct: 224 GHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 287 TFSSAGDDKLVFIW 300
+ DD IW
Sbjct: 284 LLLAGYDDFNCNIW 297
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S+ LWD+R +M F GH+ + V F +G
Sbjct: 182 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S D T R++ M+ +H + SV FS G ++ DD +W
Sbjct: 242 TTGSDDATCRLFDLRADQELLMY-SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 105 bits (252), Expect = 8e-22
Identities = 70/293 (23%), Positives = 130/293 (44%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + T G+ + + H+ + +F D ++IIT+S D
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + F GH+ V ++ DG S + D S KLW++ C T+ +
Sbjct: 167 ALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+A+ P+G + +L+D+R + YS N +T VA SG +L
Sbjct: 227 SDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D I D ++G L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 83.8 bits (198), Expect = 3e-15
Identities = 60/254 (23%), Positives = 105/254 (41%), Gaps = 8/254 (3%)
Query: 54 MRSYR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
MR+ R +GH + + + + + + SAS+D + IW T S V +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA 104
Query: 113 FSSDGSKIITASDDKVVKLWSTHKH----KFISSFVGHTNWVRCARMSNDGSIIASCSDD 168
++ G+ + D + ++S + GHT ++ C R +D II S S D
Sbjct: 105 YAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGD 163
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS 228
+ LW++++G+ + G + L+ P G ++KL+D+R Q +
Sbjct: 164 TTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFI 223
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN--GPVNAVNFSPTGD 286
H + VA P+G T S D ++ DL + S N + +V FS +G
Sbjct: 224 GHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 287 TFSSAGDDKLVFIW 300
+ DD IW
Sbjct: 284 LLLAGYDDFNCNIW 297
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S+ LWD+R +M F GH+ + V F +G
Sbjct: 182 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S D T R++ M+ +H + SV FS G ++ DD +W
Sbjct: 242 TTGSDDATCRLFDLRADQELLMY-SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide binding
protein beta 2 protein.
Length = 340
Score = 105 bits (252), Expect = 8e-22
Identities = 70/293 (23%), Positives = 130/293 (44%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + T G+ + + H+ + +F D ++IIT+S D
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + F GH+ V ++ DG S + D S KLW++ C T+ +
Sbjct: 167 ALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+A+ P+G + +L+D+R + YS N +T VA SG +L
Sbjct: 227 SDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D I D ++G L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 83.8 bits (198), Expect = 3e-15
Identities = 60/254 (23%), Positives = 105/254 (41%), Gaps = 8/254 (3%)
Query: 54 MRSYR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
MR+ R +GH + + + + + + SAS+D + IW T S V +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA 104
Query: 113 FSSDGSKIITASDDKVVKLWSTHKH----KFISSFVGHTNWVRCARMSNDGSIIASCSDD 168
++ G+ + D + ++S + GHT ++ C R +D II S S D
Sbjct: 105 YAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGD 163
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS 228
+ LW++++G+ + G + L+ P G ++KL+D+R Q +
Sbjct: 164 TTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFI 223
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN--GPVNAVNFSPTGD 286
H + VA P+G T S D ++ DL + S N + +V FS +G
Sbjct: 224 GHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 287 TFSSAGDDKLVFIW 300
+ DD IW
Sbjct: 284 LLLAGYDDFNCNIW 297
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S+ LWD+R +M F GH+ + V F +G
Sbjct: 182 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S D T R++ M+ +H + SV FS G ++ DD +W
Sbjct: 242 TTGSDDATCRLFDLRADQELLMY-SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 105 bits (252), Expect = 8e-22
Identities = 70/293 (23%), Positives = 130/293 (44%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + T G+ + + H+ + +F D ++IIT+S D
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + F GH+ V ++ DG S + D S KLW++ C T+ +
Sbjct: 167 ALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+A+ P+G + +L+D+R + YS N +T VA SG +L
Sbjct: 227 SDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D I D ++G L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 83.8 bits (198), Expect = 3e-15
Identities = 60/254 (23%), Positives = 105/254 (41%), Gaps = 8/254 (3%)
Query: 54 MRSYR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
MR+ R +GH + + + + + + SAS+D + IW T S V +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA 104
Query: 113 FSSDGSKIITASDDKVVKLWSTHKH----KFISSFVGHTNWVRCARMSNDGSIIASCSDD 168
++ G+ + D + ++S + GHT ++ C R +D II S S D
Sbjct: 105 YAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGD 163
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS 228
+ LW++++G+ + G + L+ P G ++KL+D+R Q +
Sbjct: 164 TTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFI 223
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN--GPVNAVNFSPTGD 286
H + VA P+G T S D ++ DL + S N + +V FS +G
Sbjct: 224 GHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 287 TFSSAGDDKLVFIW 300
+ DD IW
Sbjct: 284 LLLAGYDDFNCNIW 297
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S+ LWD+R +M F GH+ + V F +G
Sbjct: 182 GHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S D T R++ M+ +H + SV FS G ++ DD +W
Sbjct: 242 TTGSDDATCRLFDLRADQELLMY-SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC127949-1|AAI27950.1| 314|Homo sapiens similar to hypothetical
protein FLJ25955 protein.
Length = 314
Score = 104 bits (250), Expect = 1e-21
Identities = 71/279 (25%), Positives = 123/279 (44%), Gaps = 4/279 (1%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMA 79
H + + ++P+ Q + T S D V W+ R +R GH V FS G A
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 80 SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKF 139
SAS D TVR+W + K H ++V +V FS D ++ + DK V LW +
Sbjct: 80 SASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM 139
Query: 140 ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LA 196
+ VGH + ++ + S + +A+ S D + ++W+L +++ L+GH + L
Sbjct: 140 LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNISCLC 199
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMK 256
+ SG +A + + ++ T +L+ H V +A P ++ +A +K
Sbjct: 200 YSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVK 258
Query: 257 ILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ D G + TL G + F+P G S D+
Sbjct: 259 VWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQ 297
Score = 100 bits (239), Expect = 3e-20
Identities = 53/193 (27%), Positives = 95/193 (49%), Gaps = 5/193 (2%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ LKGH+ ++ + ++P+ +Q+A+ D V+LWD++ GH +++ F
Sbjct: 97 CLRV-LKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDF 155
Query: 72 SSSGKYMASASRDKTVRIW---VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
S + +A+ S D TVRIW + T S + HS + + +S+ G + + S DK
Sbjct: 156 SPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNISCLCYSASG-LLASGSWDKT 214
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+ +W + GH WV+ S D +AS + K+W+ ++G+C+ T K +
Sbjct: 215 IHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGV 274
Query: 189 KGHGLHLAWHPSG 201
A+ P G
Sbjct: 275 LDVAHTCAFTPDG 287
Score = 95.1 bits (226), Expect = 1e-18
Identities = 58/215 (26%), Positives = 102/215 (47%), Gaps = 4/215 (1%)
Query: 101 FKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS 160
F H V S FS DG ++T S+D V W T + + GHT V+ R S DG
Sbjct: 17 FGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGH 76
Query: 161 IIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRT 220
+ AS S D + +LW++ +C+ K + +++ P +A V L+D+++
Sbjct: 77 LFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQS 136
Query: 221 HNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFT---LSGHNGPVN 277
+++ H +++ P+ + + T S D ++I DL P + L GH+G ++
Sbjct: 137 GQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNIS 196
Query: 278 AVNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESK 312
+ +S +G +S DK + IWK + L + K
Sbjct: 197 CLCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLK 230
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/159 (30%), Positives = 83/159 (52%), Gaps = 4/159 (2%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ---GHDEAVMDVTFSS 73
L GH+++I + ++P +AT S D++V +WDLR + Q GH + + +S+
Sbjct: 143 LVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNISCLCYSA 202
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
SG +AS S DKT+ IW PT + K H V+S+ FS D + +A ++VK+W
Sbjct: 203 SG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWD 261
Query: 134 THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTK 172
+ K + + G + + DG I+ S + D++ +
Sbjct: 262 CNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQTRR 300
Score = 79.0 bits (186), Expect = 7e-14
Identities = 60/243 (24%), Positives = 106/243 (43%), Gaps = 10/243 (4%)
Query: 16 QLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
+L GH + ++P+ A++S D +V LWD+ +GH +V V+FS
Sbjct: 58 RLGGHTGPVKFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDS 117
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ +AS DK V +W + H +++S FS + + T S D V++W
Sbjct: 118 RQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLR 177
Query: 136 K-HKFIS--SFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+S + GH+ + C S G ++AS S DK+ +W + + LKGH
Sbjct: 178 MVTPAVSHQALEGHSGNISCLCYSASG-LLASGSWDKTIHIWKPTTSSLL---IQLKGHV 233
Query: 193 L---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
+A+ P ++A A VK++D T ++ + A P G +++
Sbjct: 234 TWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSG 293
Query: 250 SKD 252
+ D
Sbjct: 294 AAD 296
Score = 76.6 bits (180), Expect = 4e-13
Identities = 63/254 (24%), Positives = 106/254 (41%), Gaps = 5/254 (1%)
Query: 54 MRSYRFQG-HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
+R +F G H V FS G+ + + S D V W H+ V+ +
Sbjct: 11 VRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCR 70
Query: 113 FSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTK 172
FS DG +AS D V+LW + K + GH V S D +AS DK
Sbjct: 71 FSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVM 130
Query: 173 LWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHN-LVQYYSI-- 229
LW++ SG+ + + + P+ +A + V+++D+R V + ++
Sbjct: 131 LWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEG 190
Query: 230 HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFS 289
H+ ++ + SG + + S D + I + L GH V ++ FSP +
Sbjct: 191 HSGNISCLCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLA 249
Query: 290 SAGDDKLVFIWKTN 303
SAG ++V +W N
Sbjct: 250 SAGYSRMVKVWDCN 263
Score = 60.9 bits (141), Expect = 2e-08
Identities = 39/179 (21%), Positives = 72/179 (40%)
Query: 140 ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHP 199
+ F H V + S DG ++ + S+D W SG+ + G + P
Sbjct: 14 VKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSP 73
Query: 200 SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
G A A+ V+L+D+ ++ H +V V+ P + + D ++ + D
Sbjct: 74 DGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD 133
Query: 260 LLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEGQN 318
+ G + L GH + + +FSPT + ++ D V IW + + EG +
Sbjct: 134 VQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHS 192
>AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38
protein.
Length = 314
Score = 104 bits (250), Expect = 1e-21
Identities = 71/279 (25%), Positives = 122/279 (43%), Gaps = 4/279 (1%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMA 79
H + + ++P+ Q + T S D V W+ R +R GH V FS G A
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 80 SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKF 139
SAS D TVR+W + K H ++V +V FS D ++ + DK V LW +
Sbjct: 80 SASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM 139
Query: 140 ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LA 196
+ VGH + ++ + S + +A+ S D + +W+L +++ L+GH + L
Sbjct: 140 LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLC 199
Query: 197 WHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMK 256
+ SG +A + + ++ T +L+ H V +A P ++ +A +K
Sbjct: 200 YSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVK 258
Query: 257 ILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ D G + TL G + F+P G S D+
Sbjct: 259 VWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQ 297
Score = 98.7 bits (235), Expect = 9e-20
Identities = 52/193 (26%), Positives = 94/193 (48%), Gaps = 5/193 (2%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ LKGH+ ++ + ++P+ +Q+A+ D V+LWD++ GH +++ F
Sbjct: 97 CLRV-LKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDF 155
Query: 72 SSSGKYMASASRDKTVRIW---VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
S + +A+ S D TV IW + T S + HS + + +S+ G + + S DK
Sbjct: 156 SPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASG-LLASGSWDKT 214
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+ +W + GH WV+ S D +AS + K+W+ ++G+C+ T K +
Sbjct: 215 IHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGV 274
Query: 189 KGHGLHLAWHPSG 201
A+ P G
Sbjct: 275 LDVAHTCAFTPDG 287
Score = 91.5 bits (217), Expect = 1e-17
Identities = 57/215 (26%), Positives = 100/215 (46%), Gaps = 4/215 (1%)
Query: 101 FKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS 160
F H V S FS DG ++T S+D V W T + + GHT V+ R S DG
Sbjct: 17 FGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGH 76
Query: 161 IIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRT 220
+ AS S D + +LW++ +C+ K + +++ P +A V L+D+++
Sbjct: 77 LFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQS 136
Query: 221 HNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFT---LSGHNGPVN 277
+++ H +++ P+ + + T S D + I DL P + L GH+ ++
Sbjct: 137 GQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANIS 196
Query: 278 AVNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESK 312
+ +S +G +S DK + IWK + L + K
Sbjct: 197 CLCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLK 230
Score = 85.0 bits (201), Expect = 1e-15
Identities = 48/159 (30%), Positives = 83/159 (52%), Gaps = 4/159 (2%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ---GHDEAVMDVTFSS 73
L GH+++I + ++P +AT S D++V +WDLR + Q GH + + +S+
Sbjct: 143 LVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSA 202
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
SG +AS S DKT+ IW PT + K H V+S+ FS D + +A ++VK+W
Sbjct: 203 SG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWD 261
Query: 134 THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTK 172
+ K + + G + + DG I+ S + D++ +
Sbjct: 262 CNTGKCLETLKGVLDVAHTCAFTPDGKILVSGAADQTRR 300
Score = 77.0 bits (181), Expect = 3e-13
Identities = 60/243 (24%), Positives = 105/243 (43%), Gaps = 10/243 (4%)
Query: 16 QLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
+L GH + ++P+ A++S D +V LWD+ +GH +V V+FS
Sbjct: 58 RLGGHTGPVKFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDS 117
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ +AS DK V +W + H +++S FS + + T S D V +W
Sbjct: 118 RQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLR 177
Query: 136 K-HKFIS--SFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+S + GH+ + C S G ++AS S DK+ +W + + LKGH
Sbjct: 178 MVTPAVSHQALEGHSANISCLCYSASG-LLASGSWDKTIHIWKPTTSSLL---IQLKGHV 233
Query: 193 L---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
+A+ P ++A A VK++D T ++ + A P G +++
Sbjct: 234 TWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFTPDGKILVSG 293
Query: 250 SKD 252
+ D
Sbjct: 294 AAD 296
Score = 76.2 bits (179), Expect = 5e-13
Identities = 63/253 (24%), Positives = 103/253 (40%), Gaps = 3/253 (1%)
Query: 54 MRSYRFQG-HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
+R +F G H V FS G+ + + S D V W H+ V+ +
Sbjct: 11 VRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCR 70
Query: 113 FSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTK 172
FS DG +AS D V+LW + K + GH V S D +AS DK
Sbjct: 71 FSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVM 130
Query: 173 LWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHN-LVQYYSIHN 231
LW++ SG+ + + + P+ +A + V ++D+R V + ++
Sbjct: 131 LWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEG 190
Query: 232 EAVTQVAIHPSGSYILTA-SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSS 290
+ + S S +L + S D + I + L GH V ++ FSP +S
Sbjct: 191 HSANISCLCYSASGLLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLAS 250
Query: 291 AGDDKLVFIWKTN 303
AG ++V +W N
Sbjct: 251 AGYSRMVKVWDCN 263
Score = 61.7 bits (143), Expect = 1e-08
Identities = 39/179 (21%), Positives = 72/179 (40%)
Query: 140 ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHP 199
+ F H V + S DG ++ + S+D W SG+ + G + P
Sbjct: 14 VKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSP 73
Query: 200 SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
G A A+ V+L+D+ ++ H +V V+ P + + D ++ + D
Sbjct: 74 DGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD 133
Query: 260 LLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEGQN 318
+ G + L GH + + +FSPT + ++ D V IW + + EG +
Sbjct: 134 VQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHS 192
>BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein.
Length = 332
Score = 104 bits (249), Expect = 2e-21
Identities = 67/283 (23%), Positives = 128/283 (45%), Gaps = 7/283 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG Y+A D I+ + T G+ + + H+ + +F D ++I+T+S D
Sbjct: 108 SGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + ++F GHT V ++ D + S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+ + P+G A + +L+D+R + YS N +T V+ SG +L
Sbjct: 227 SDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSS 290
D + D L+ L+GH+ V+ + + G +S
Sbjct: 287 AGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVAS 329
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/196 (22%), Positives = 91/196 (46%), Gaps = 3/196 (1%)
Query: 102 KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
+ H + ++ + +D +++AS D + +W ++ + + ++WV + G+
Sbjct: 52 RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNY 111
Query: 162 IASCSDDKSTKLWNLDSGEC-IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVK--LYDI 218
+A D ++NL + E + ++L GH +L+ + TS G+ L+DI
Sbjct: 112 VACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDI 171
Query: 219 RTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNA 278
T ++ H V +++ P ++ + D K+ D+ EG T +GH +NA
Sbjct: 172 ETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINA 231
Query: 279 VNFSPTGDTFSSAGDD 294
+ F P G+ F++ DD
Sbjct: 232 ICFFPNGNAFATGSDD 247
Score = 49.6 bits (113), Expect = 5e-05
Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 4/114 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN AT S D + L+DLR + HD + +
Sbjct: 215 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKI 120
T FS SG+ + + D +W G+ H V + + DG +
Sbjct: 274 TSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAV 327
Score = 46.4 bits (105), Expect = 5e-04
Identities = 34/159 (21%), Positives = 59/159 (37%), Gaps = 3/159 (1%)
Query: 145 GHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYV 204
GH + D ++ S S D +W+ + +H + A+ PSG YV
Sbjct: 53 GHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYV 112
Query: 205 AVATSHGNVKLYDIRTHN---LVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLL 261
A +Y+++T V + + I+T+S D + D+
Sbjct: 113 ACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIE 172
Query: 262 EGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
G T +GH G V +++ +P F S D +W
Sbjct: 173 TGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLW 211
>M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human
signal-transducing guanine nucleotide-binding regulatory
(G) protein beta subunit mRNA, complete cds. ).
Length = 340
Score = 103 bits (248), Expect = 2e-21
Identities = 69/293 (23%), Positives = 130/293 (44%), Gaps = 7/293 (2%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAX 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + T G+ + + H+ + +F D ++IIT+S D
Sbjct: 108 SGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + F GH+ V ++ +G S + D S KLW++ C T+ +
Sbjct: 167 ALWDIETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTFIGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAIHPSGSYIL 247
+A+ P+G + +L+D+R + YS N +T VA SG +L
Sbjct: 227 SDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLL 286
Query: 248 TASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D I D ++G L+GH+ V+ + + G ++ D + IW
Sbjct: 287 AGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 84.6 bits (200), Expect = 2e-15
Identities = 60/254 (23%), Positives = 106/254 (41%), Gaps = 8/254 (3%)
Query: 54 MRSYR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ 112
MR+ R +GH + + + + + + SAS+D + IW T S V +
Sbjct: 45 MRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCA 104
Query: 113 FSSDGSKIITASDDKVVKLWSTHKH----KFISSFVGHTNWVRCARMSNDGSIIASCSDD 168
++ G+ + D + ++S + GHT ++ C R +D II S S D
Sbjct: 105 YAXSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITS-SGD 163
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS 228
+ LW++++G+ + G + L+ P+G ++KL+D+R Q +
Sbjct: 164 TTCALWDIETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTFI 223
Query: 229 IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN--GPVNAVNFSPTGD 286
H + VA P+G T S D ++ DL + S N + +V FS +G
Sbjct: 224 GHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGR 283
Query: 287 TFSSAGDDKLVFIW 300
+ DD IW
Sbjct: 284 LLLAGYDDFNCNIW 297
Score = 79.8 bits (188), Expect = 4e-14
Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L PN + + + D S+ LWD+R +M F GH+ + V F +G
Sbjct: 182 GHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAF 241
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQT---VRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ S D T R++ M+ +H + SV FS G ++ DD +W
Sbjct: 242 TTGSDDATCRLFDLRADQELLMY-SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/171 (23%), Positives = 78/171 (45%), Gaps = 5/171 (2%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
+ ++L GH ++ + +D QI TSS D + LWD+ ++ F GH VM ++ +
Sbjct: 135 VSRELPGHTGYLSCCRFL-DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLA 193
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+G+ S + D ++++W + F H + +V F +G T SDD +L+
Sbjct: 194 PNGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLF 253
Query: 133 STHKHKFISSFVGHTN---WVRCARMSNDGSIIASCSDDKSTKLWNLDSGE 180
+ + + H N + S G ++ + DD + +W+ G+
Sbjct: 254 DLRADQELLMY-SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGD 303
>BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 103 bits (247), Expect = 3e-21
Identities = 77/310 (24%), Positives = 146/310 (47%), Gaps = 23/310 (7%)
Query: 13 LKKQLK-GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRS---YRFQGH----D 63
L + +K G K+ + ++P+ Q + T S+D + +W+ G +R Y+ Q + D
Sbjct: 205 LSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMD 264
Query: 64 EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIIT 122
+AV+ + FS + +A+ ++D +++W F +AHS+ V + FS D S+I++
Sbjct: 265 DAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILS 324
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECI 182
AS D+ +++ K + F GH+++V A + DG I S S D + K+WN+ + EC
Sbjct: 325 ASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECS 384
Query: 183 HTYKDLKGHG---------LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
+T+K L + L +P + V V + +++ + + S E
Sbjct: 385 NTFKSLGSTAGTDITVNSVILLPKNPE--HFVVCNRSNTVVIMNMQGQIVRSFSSGKREG 442
Query: 234 VTQV--AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSA 291
V A+ P G +I +D + + G TL+ H V + P + ++
Sbjct: 443 GDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIATY 502
Query: 292 GDDKLVFIWK 301
+D L+ +WK
Sbjct: 503 SEDALLKLWK 512
Score = 65.3 bits (152), Expect = 1e-09
Identities = 59/264 (22%), Positives = 113/264 (42%), Gaps = 26/264 (9%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQ--------TVRSVQ 112
G V FS G+Y+ + S D + +W T K +Q V +
Sbjct: 212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMC 271
Query: 113 FSSDGSKIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKST 171
FS D + T + D +K+W + + F H+ V C S D S I S S D++
Sbjct: 272 FSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTI 331
Query: 172 KLWNLDSGECIHTYKDLKGHGLHL---AWHPSGCYVAVATSHGNVKLYDIRTHNLVQ-YY 227
++ L SG+ T K+ +GH + + G Y+ A+S G VK+++++T +
Sbjct: 332 RIHGLKSGK---TLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFK 388
Query: 228 SIHNEAVTQVAIH------PSGSYILTASKDGKMKILDLLEGHPIFTLSG---HNGPVNA 278
S+ + A T + ++ + + + ++ + I++ ++G + + S G
Sbjct: 389 SLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMN-MQGQIVRSFSSGKREGGDFVC 447
Query: 279 VNFSPTGDTFSSAGDDKLVFIWKT 302
SP G+ G+D +++ + T
Sbjct: 448 CALSPRGEWIYCVGEDFVLYCFST 471
Score = 65.3 bits (152), Expect = 1e-09
Identities = 30/96 (31%), Positives = 50/96 (52%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL++ + H +T L ++ + QI ++S D ++ + L+ F+GH V + TF
Sbjct: 298 CLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATF 357
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQT 107
+ G Y+ SAS D TV+IW T + FK+ T
Sbjct: 358 TQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGST 393
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/180 (27%), Positives = 79/180 (43%), Gaps = 15/180 (8%)
Query: 145 GHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG-----------L 193
G + V CAR S DG + + S D ++WN +G+ KDLK L
Sbjct: 212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKI---RKDLKYQAQDNFMMMDDAVL 268
Query: 194 HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYS-IHNEAVTQVAIHPSGSYILTASKD 252
+ + +A G +K++ I++ ++ + H++ VT ++ S IL+AS D
Sbjct: 269 CMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFD 328
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESK 312
++I L G + GH+ VN F+ G SA D V IW T+ S+ K
Sbjct: 329 QTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFK 388
>EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein.
Length = 513
Score = 103 bits (246), Expect = 4e-21
Identities = 77/310 (24%), Positives = 146/310 (47%), Gaps = 23/310 (7%)
Query: 13 LKKQLK-GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRS---YRFQGH----D 63
L + +K G K+ + ++P+ Q + T S+D + +W+ G +R Y+ Q + D
Sbjct: 205 LSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMD 264
Query: 64 EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIIT 122
+AV+ + FS + +A+ ++D +++W F +AHS+ V + FS D S+I++
Sbjct: 265 DAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILS 324
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECI 182
AS D+ +++ K + F GH+++V A + DG I S S D + K+WN+ + EC
Sbjct: 325 ASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECS 384
Query: 183 HTYKDLKGHG---------LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
+T+K L + L +P + V V + +++ + + S E
Sbjct: 385 NTFKSLGSTAGTDITVNSVILLPKNPE--HFVVCNRSNTVVIMNMQGQIVRSFSSGKREG 442
Query: 234 VTQV--AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSA 291
V A+ P G +I +D + + G TL+ H V + P + ++
Sbjct: 443 GDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIATY 502
Query: 292 GDDKLVFIWK 301
+D L+ +WK
Sbjct: 503 SEDGLLKLWK 512
Score = 67.3 bits (157), Expect = 2e-10
Identities = 67/303 (22%), Positives = 130/303 (42%), Gaps = 27/303 (8%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQ--------TVRSVQ 112
G V FS G+Y+ + S D + +W T K +Q V +
Sbjct: 212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMC 271
Query: 113 FSSDGSKIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKST 171
FS D + T + D +K+W + + F H+ V C S D S I S S D++
Sbjct: 272 FSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTI 331
Query: 172 KLWNLDSGECIHTYKDLKGHGLHL---AWHPSGCYVAVATSHGNVKLYDIRTHNLVQ-YY 227
++ L SG+ T K+ +GH + + G Y+ A+S G VK+++++T +
Sbjct: 332 RIHGLKSGK---TLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFK 388
Query: 228 SIHNEAVTQVAIH------PSGSYILTASKDGKMKILDLLEGHPIFTLSG---HNGPVNA 278
S+ + A T + ++ + + + ++ + I++ ++G + + S G
Sbjct: 389 SLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMN-MQGQIVRSFSSGKREGGDFVC 447
Query: 279 VNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENG 338
SP G+ G+D +++ + T L +E +++I H + I T +E+G
Sbjct: 448 CALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHE-KDVIGIAHHPHQNLIATYSEDG 506
Query: 339 QIQ 341
++
Sbjct: 507 LLK 509
Score = 65.3 bits (152), Expect = 1e-09
Identities = 30/96 (31%), Positives = 50/96 (52%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL++ + H +T L ++ + QI ++S D ++ + L+ F+GH V + TF
Sbjct: 298 CLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATF 357
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQT 107
+ G Y+ SAS D TV+IW T + FK+ T
Sbjct: 358 TQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGST 393
>BC130473-1|AAI30474.1| 522|Homo sapiens transducin (beta)-like
1Y-linked protein.
Length = 522
Score = 103 bits (246), Expect = 4e-21
Identities = 73/288 (25%), Positives = 123/288 (42%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N + +A S D +W G + S Q H + + ++ G Y+ SA
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQ-HKGPIFALKWNKKGNYVLSAGV 296
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + ++ + + S D + + + +F
Sbjct: 297 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMT-FASCSTDMCIHVCRLGCDHPVKTF 355
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G ++ASCSDD + K+W++ C+H DL+ H + W P+
Sbjct: 356 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVH---DLQAHSKEIYTIKWSPT 412
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+D+ H E V VA P G Y+ + S
Sbjct: 413 GPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSF 472
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G + + G G + V ++ GD ++ D V +
Sbjct: 473 DKYVHIWNTQSGSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSVCV 519
Score = 95.5 bits (227), Expect = 8e-19
Identities = 78/313 (24%), Positives = 134/313 (42%), Gaps = 33/313 (10%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L Q GHD
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++S G +A S D RIW T G+ H + +++++ G+ ++
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIW--TENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ N+ + ASCS D + L C
Sbjct: 293 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTF-ASCSTDMCIHVCRLG---C 348
Query: 182 IHTYKDLKGHGLH---LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
H K +GH + W PSG +A + +K++ ++ V H++ + +
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIK 408
Query: 239 IHPSGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFS 289
P+G + +AS D +++ D+ +G TL H PV +V FSP G +
Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLA 468
Query: 290 SAGDDKLVFIWKT 302
S DK V IW T
Sbjct: 469 SGSFDKYVHIWNT 481
Score = 95.5 bits (227), Expect = 8e-19
Identities = 59/265 (22%), Positives = 118/265 (44%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T L L HK I AL +N + ++ +D + ++WD +F H
Sbjct: 260 RIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSA 319
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + ++ + AS S D + + F+ H+ V ++++ G + + S
Sbjct: 320 PALDVDWQNNMTF-ASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCS 378
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + + H+ + + S N ++AS S D + +LW+
Sbjct: 379 DDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD 438
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
++ G C HT + +A+ P G Y+A + V +++ ++ +LV Y +
Sbjct: 439 VEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQ-GTGGIF 497
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + G + ++ DG + +LDL
Sbjct: 498 EVCWNARGDKVGASASDGSVCVLDL 522
>BC130471-1|AAI30472.1| 522|Homo sapiens transducin (beta)-like
1Y-linked protein.
Length = 522
Score = 103 bits (246), Expect = 4e-21
Identities = 73/288 (25%), Positives = 123/288 (42%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N + +A S D +W G + S Q H + + ++ G Y+ SA
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQ-HKGPIFALKWNKKGNYVLSAGV 296
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + ++ + + S D + + + +F
Sbjct: 297 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMT-FASCSTDMCIHVCRLGCDHPVKTF 355
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G ++ASCSDD + K+W++ C+H DL+ H + W P+
Sbjct: 356 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVH---DLQAHSKEIYTIKWSPT 412
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+D+ H E V VA P G Y+ + S
Sbjct: 413 GPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSF 472
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G + + G G + V ++ GD ++ D V +
Sbjct: 473 DKYVHIWNTQSGSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSVCV 519
Score = 95.5 bits (227), Expect = 8e-19
Identities = 78/313 (24%), Positives = 134/313 (42%), Gaps = 33/313 (10%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L Q GHD
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++S G +A S D RIW T G+ H + +++++ G+ ++
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIW--TENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ N+ + ASCS D + L C
Sbjct: 293 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTF-ASCSTDMCIHVCRLG---C 348
Query: 182 IHTYKDLKGHGLH---LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
H K +GH + W PSG +A + +K++ ++ V H++ + +
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIK 408
Query: 239 IHPSGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFS 289
P+G + +AS D +++ D+ +G TL H PV +V FSP G +
Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLA 468
Query: 290 SAGDDKLVFIWKT 302
S DK V IW T
Sbjct: 469 SGSFDKYVHIWNT 481
Score = 95.5 bits (227), Expect = 8e-19
Identities = 59/265 (22%), Positives = 118/265 (44%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T L L HK I AL +N + ++ +D + ++WD +F H
Sbjct: 260 RIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSA 319
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + ++ + AS S D + + F+ H+ V ++++ G + + S
Sbjct: 320 PALDVDWQNNMTF-ASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCS 378
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + + H+ + + S N ++AS S D + +LW+
Sbjct: 379 DDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD 438
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
++ G C HT + +A+ P G Y+A + V +++ ++ +LV Y +
Sbjct: 439 VEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQ-GTGGIF 497
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + G + ++ DG + +LDL
Sbjct: 498 EVCWNARGDKVGASASDGSVCVLDL 522
>BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 103 bits (246), Expect = 4e-21
Identities = 77/310 (24%), Positives = 146/310 (47%), Gaps = 23/310 (7%)
Query: 13 LKKQLK-GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRS---YRFQGH----D 63
L + +K G K+ + ++P+ Q + T S+D + +W+ G +R Y+ Q + D
Sbjct: 205 LSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMD 264
Query: 64 EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIIT 122
+AV+ + FS + +A+ ++D +++W F +AHS+ V + FS D S+I++
Sbjct: 265 DAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILS 324
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECI 182
AS D+ +++ K + F GH+++V A + DG I S S D + K+WN+ + EC
Sbjct: 325 ASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECS 384
Query: 183 HTYKDLKGHG---------LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
+T+K L + L +P + V V + +++ + + S E
Sbjct: 385 NTFKSLGSTAGTDITVNSVILLPKNPE--HFVVCNRSNTVVIMNMQGQIVRSFSSGKREG 442
Query: 234 VTQV--AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSA 291
V A+ P G +I +D + + G TL+ H V + P + ++
Sbjct: 443 GDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIATY 502
Query: 292 GDDKLVFIWK 301
+D L+ +WK
Sbjct: 503 SEDGLLKLWK 512
Score = 67.3 bits (157), Expect = 2e-10
Identities = 67/303 (22%), Positives = 130/303 (42%), Gaps = 27/303 (8%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQ--------TVRSVQ 112
G V FS G+Y+ + S D + +W T K +Q V +
Sbjct: 212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMC 271
Query: 113 FSSDGSKIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKST 171
FS D + T + D +K+W + + F H+ V C S D S I S S D++
Sbjct: 272 FSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTI 331
Query: 172 KLWNLDSGECIHTYKDLKGHGLHL---AWHPSGCYVAVATSHGNVKLYDIRTHNLVQ-YY 227
++ L SG+ T K+ +GH + + G Y+ A+S G VK+++++T +
Sbjct: 332 RIHGLKSGK---TLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFK 388
Query: 228 SIHNEAVTQVAIH------PSGSYILTASKDGKMKILDLLEGHPIFTLSG---HNGPVNA 278
S+ + A T + ++ + + + ++ + I++ ++G + + S G
Sbjct: 389 SLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMN-MQGQIVRSFSSGKREGGDFVC 447
Query: 279 VNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENG 338
SP G+ G+D +++ + T L +E +++I H + I T +E+G
Sbjct: 448 CALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHE-KDVIGIAHHPHQNLIATYSEDG 506
Query: 339 QIQ 341
++
Sbjct: 507 LLK 509
Score = 65.3 bits (152), Expect = 1e-09
Identities = 30/96 (31%), Positives = 50/96 (52%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL++ + H +T L ++ + QI ++S D ++ + L+ F+GH V + TF
Sbjct: 298 CLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATF 357
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQT 107
+ G Y+ SAS D TV+IW T + FK+ T
Sbjct: 358 TQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGST 393
>AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 103 bits (246), Expect = 4e-21
Identities = 77/310 (24%), Positives = 146/310 (47%), Gaps = 23/310 (7%)
Query: 13 LKKQLK-GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRS---YRFQGH----D 63
L + +K G K+ + ++P+ Q + T S+D + +W+ G +R Y+ Q + D
Sbjct: 205 LSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMD 264
Query: 64 EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIIT 122
+AV+ + FS + +A+ ++D +++W F +AHS+ V + FS D S+I++
Sbjct: 265 DAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILS 324
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECI 182
AS D+ +++ K + F GH+++V A + DG I S S D + K+WN+ + EC
Sbjct: 325 ASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECS 384
Query: 183 HTYKDLKGHG---------LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
+T+K L + L +P + V V + +++ + + S E
Sbjct: 385 NTFKSLGSTAGTDITVNSVILLPKNPE--HFVVCNRSNTVVIMNMQGQIVRSFSSGKREG 442
Query: 234 VTQV--AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSA 291
V A+ P G +I +D + + G TL+ H V + P + ++
Sbjct: 443 GDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIATY 502
Query: 292 GDDKLVFIWK 301
+D L+ +WK
Sbjct: 503 SEDGLLKLWK 512
Score = 67.3 bits (157), Expect = 2e-10
Identities = 67/303 (22%), Positives = 130/303 (42%), Gaps = 27/303 (8%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQ--------TVRSVQ 112
G V FS G+Y+ + S D + +W T K +Q V +
Sbjct: 212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMC 271
Query: 113 FSSDGSKIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKST 171
FS D + T + D +K+W + + F H+ V C S D S I S S D++
Sbjct: 272 FSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTI 331
Query: 172 KLWNLDSGECIHTYKDLKGHGLHL---AWHPSGCYVAVATSHGNVKLYDIRTHNLVQ-YY 227
++ L SG+ T K+ +GH + + G Y+ A+S G VK+++++T +
Sbjct: 332 RIHGLKSGK---TLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFK 388
Query: 228 SIHNEAVTQVAIH------PSGSYILTASKDGKMKILDLLEGHPIFTLSG---HNGPVNA 278
S+ + A T + ++ + + + ++ + I++ ++G + + S G
Sbjct: 389 SLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMN-MQGQIVRSFSSGKREGGDFVC 447
Query: 279 VNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENG 338
SP G+ G+D +++ + T L +E +++I H + I T +E+G
Sbjct: 448 CALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHE-KDVIGIAHHPHQNLIATYSEDG 506
Query: 339 QIQ 341
++
Sbjct: 507 LLK 509
Score = 65.3 bits (152), Expect = 1e-09
Identities = 30/96 (31%), Positives = 50/96 (52%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL++ + H +T L ++ + QI ++S D ++ + L+ F+GH V + TF
Sbjct: 298 CLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATF 357
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQT 107
+ G Y+ SAS D TV+IW T + FK+ T
Sbjct: 358 TQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGST 393
>AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens
cDNA FLJ10805 fis, clone NT2RP4000839, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 513
Score = 103 bits (246), Expect = 4e-21
Identities = 77/310 (24%), Positives = 146/310 (47%), Gaps = 23/310 (7%)
Query: 13 LKKQLK-GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRS---YRFQGH----D 63
L + +K G K+ + ++P+ Q + T S+D + +W+ G +R Y+ Q + D
Sbjct: 205 LSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMD 264
Query: 64 EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIIT 122
+AV+ + FS + +A+ ++D +++W F +AHS+ V + FS D S+I++
Sbjct: 265 DAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILS 324
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECI 182
AS D+ +++ K + F GH+++V A + DG I S S D + K+WN+ + EC
Sbjct: 325 ASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECS 384
Query: 183 HTYKDLKGHG---------LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
+T+K L + L +P + V V + +++ + + S E
Sbjct: 385 NTFKSLGSTAGTDITVNSVILLPKNPE--HFVVCNRSNTVVIMNMQGQIVRSFSSGKREG 442
Query: 234 VTQV--AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSA 291
V A+ P G +I +D + + G TL+ H V + P + ++
Sbjct: 443 GDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNPIATY 502
Query: 292 GDDKLVFIWK 301
+D L+ +WK
Sbjct: 503 SEDGLLKLWK 512
Score = 68.1 bits (159), Expect = 1e-10
Identities = 67/303 (22%), Positives = 130/303 (42%), Gaps = 27/303 (8%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQ--------TVRSVQ 112
G V FS G+Y+ + S D + +W T K +Q V +
Sbjct: 212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMC 271
Query: 113 FSSDGSKIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKST 171
FS D + T + D +K+W + + F H+ V C S D S I S S D++
Sbjct: 272 FSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTI 331
Query: 172 KLWNLDSGECIHTYKDLKGHGLHL---AWHPSGCYVAVATSHGNVKLYDIRTHNLVQ-YY 227
++ L SG+ T K+ +GH + + G Y+ A+S G VK+++++T +
Sbjct: 332 RIHGLKSGK---TLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFK 388
Query: 228 SIHNEAVTQVAIH------PSGSYILTASKDGKMKILDLLEGHPIFTLSG---HNGPVNA 278
S+ + A T + ++ + + + ++ + I++ ++G + + S G
Sbjct: 389 SLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMN-MQGQIVRSFSSGKREGGDFVC 447
Query: 279 VNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENG 338
SP G+ G+D +++ + T L +E +++I H + I T +E+G
Sbjct: 448 CALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHE-KDVIGIAHHPHQNPIATYSEDG 506
Query: 339 QIQ 341
++
Sbjct: 507 LLK 509
Score = 65.3 bits (152), Expect = 1e-09
Identities = 30/96 (31%), Positives = 50/96 (52%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL++ + H +T L ++ + QI ++S D ++ + L+ F+GH V + TF
Sbjct: 298 CLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATF 357
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQT 107
+ G Y+ SAS D TV+IW T + FK+ T
Sbjct: 358 TQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGST 393
>AF332222-1|AAK13474.1| 522|Homo sapiens transducin beta-like 1
protein.
Length = 522
Score = 103 bits (246), Expect = 4e-21
Identities = 73/288 (25%), Positives = 123/288 (42%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N + +A S D +W G + S Q H + + ++ G Y+ SA
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQ-HKGPIFALKWNKKGNYVLSAGV 296
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + ++ + + S D + + + +F
Sbjct: 297 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMT-FASCSTDMCIHVCRLGCDHPVKTF 355
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G ++ASCSDD + K+W++ C+H DL+ H + W P+
Sbjct: 356 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVH---DLQAHSKEIYTIKWSPT 412
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+D+ H E V VA P G Y+ + S
Sbjct: 413 GPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSF 472
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G + + G G + V ++ GD ++ D V +
Sbjct: 473 DKYVHIWNTQSGSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSVCV 519
Score = 95.5 bits (227), Expect = 8e-19
Identities = 78/313 (24%), Positives = 134/313 (42%), Gaps = 33/313 (10%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L Q GHD
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++S G +A S D RIW T G+ H + +++++ G+ ++
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIW--TENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ N+ + ASCS D + L C
Sbjct: 293 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTF-ASCSTDMCIHVCRLG---C 348
Query: 182 IHTYKDLKGHGLH---LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
H K +GH + W PSG +A + +K++ ++ V H++ + +
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIK 408
Query: 239 IHPSGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFS 289
P+G + +AS D +++ D+ +G TL H PV +V FSP G +
Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLA 468
Query: 290 SAGDDKLVFIWKT 302
S DK V IW T
Sbjct: 469 SGSFDKYVHIWNT 481
Score = 95.5 bits (227), Expect = 8e-19
Identities = 59/265 (22%), Positives = 118/265 (44%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T L L HK I AL +N + ++ +D + ++WD +F H
Sbjct: 260 RIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSA 319
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + ++ + AS S D + + F+ H+ V ++++ G + + S
Sbjct: 320 PALDVDWQNNMTF-ASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCS 378
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + + H+ + + S N ++AS S D + +LW+
Sbjct: 379 DDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD 438
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
++ G C HT + +A+ P G Y+A + V +++ ++ +LV Y +
Sbjct: 439 VEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQ-GTGGIF 497
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + G + ++ DG + +LDL
Sbjct: 498 EVCWNARGDKVGASASDGSVCVLDL 522
>AF332221-1|AAK13473.1| 522|Homo sapiens transducin beta-like 1
protein.
Length = 522
Score = 103 bits (246), Expect = 4e-21
Identities = 73/288 (25%), Positives = 123/288 (42%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N + +A S D +W G + S Q H + + ++ G Y+ SA
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQ-HKGPIFALKWNKKGNYVLSAGV 296
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + ++ + + S D + + + +F
Sbjct: 297 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMT-FASCSTDMCIHVCRLGCDHPVKTF 355
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G ++ASCSDD + K+W++ C+H DL+ H + W P+
Sbjct: 356 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVH---DLQAHSKEIYTIKWSPT 412
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+D+ H E V VA P G Y+ + S
Sbjct: 413 GPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSF 472
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G + + G G + V ++ GD ++ D V +
Sbjct: 473 DKYVHIWNTQSGSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSVCV 519
Score = 95.5 bits (227), Expect = 8e-19
Identities = 78/313 (24%), Positives = 134/313 (42%), Gaps = 33/313 (10%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L Q GHD
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++S G +A S D RIW T G+ H + +++++ G+ ++
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIW--TENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ N+ + ASCS D + L C
Sbjct: 293 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTF-ASCSTDMCIHVCRLG---C 348
Query: 182 IHTYKDLKGHGLH---LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
H K +GH + W PSG +A + +K++ ++ V H++ + +
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIK 408
Query: 239 IHPSGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFS 289
P+G + +AS D +++ D+ +G TL H PV +V FSP G +
Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLA 468
Query: 290 SAGDDKLVFIWKT 302
S DK V IW T
Sbjct: 469 SGSFDKYVHIWNT 481
Score = 95.5 bits (227), Expect = 8e-19
Identities = 59/265 (22%), Positives = 118/265 (44%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T L L HK I AL +N + ++ +D + ++WD +F H
Sbjct: 260 RIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSA 319
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + ++ + AS S D + + F+ H+ V ++++ G + + S
Sbjct: 320 PALDVDWQNNMTF-ASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCS 378
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + + H+ + + S N ++AS S D + +LW+
Sbjct: 379 DDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD 438
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
++ G C HT + +A+ P G Y+A + V +++ ++ +LV Y +
Sbjct: 439 VEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQ-GTGGIF 497
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + G + ++ DG + +LDL
Sbjct: 498 EVCWNARGDKVGASASDGSVCVLDL 522
>AF332220-1|AAK13472.1| 522|Homo sapiens transducin beta-like 1
protein.
Length = 522
Score = 103 bits (246), Expect = 4e-21
Identities = 73/288 (25%), Positives = 123/288 (42%), Gaps = 18/288 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+T+L +N + +A S D +W G + S Q H + + ++ G Y+ SA
Sbjct: 238 VTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQ-HKGPIFALKWNKKGNYVLSAGV 296
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
DKT IW + F HS V + ++ + + S D + + + +F
Sbjct: 297 DKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMT-FASCSTDMCIHVCRLGCDHPVKTF 355
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHPS 200
GHTN V + G ++ASCSDD + K+W++ C+H DL+ H + W P+
Sbjct: 356 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVH---DLQAHSKEIYTIKWSPT 412
Query: 201 G---------CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASK 251
G +A A+ V+L+D+ H E V VA P G Y+ + S
Sbjct: 413 GPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSF 472
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
D + I + G + + G G + V ++ GD ++ D V +
Sbjct: 473 DKYVHIWNTQSGSLVHSYQG-TGGIFEVCWNARGDKVGASASDGSVCV 519
Score = 95.5 bits (227), Expect = 8e-19
Identities = 78/313 (24%), Positives = 134/313 (42%), Gaps = 33/313 (10%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQ----------GHD--- 63
L+GH++ + +NP +A+ S D++ +W+L Q GHD
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 64 -EAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGS-TGMFKAHSQTVRSVQFSSDGSKII 121
+ V + ++S G +A S D RIW T G+ H + +++++ G+ ++
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIW--TENGNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
+A DK +W H + F H+ N+ + ASCS D + L C
Sbjct: 293 SAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTF-ASCSTDMCIHVCRLG---C 348
Query: 182 IHTYKDLKGHGLH---LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA 238
H K +GH + W PSG +A + +K++ ++ V H++ + +
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIK 408
Query: 239 IHPSGS---------YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFS 289
P+G + +AS D +++ D+ +G TL H PV +V FSP G +
Sbjct: 409 WSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLA 468
Query: 290 SAGDDKLVFIWKT 302
S DK V IW T
Sbjct: 469 SGSFDKYVHIWNT 481
Score = 95.5 bits (227), Expect = 8e-19
Identities = 59/265 (22%), Positives = 118/265 (44%), Gaps = 11/265 (4%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
++ T L L HK I AL +N + ++ +D + ++WD +F H
Sbjct: 260 RIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSA 319
Query: 65 AVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+DV + ++ + AS S D + + F+ H+ V ++++ G + + S
Sbjct: 320 PALDVDWQNNMTF-ASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCS 378
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMS---------NDGSIIASCSDDKSTKLWN 175
DD +K+WS + + H+ + + S N ++AS S D + +LW+
Sbjct: 379 DDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD 438
Query: 176 LDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
++ G C HT + +A+ P G Y+A + V +++ ++ +LV Y +
Sbjct: 439 VEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQ-GTGGIF 497
Query: 236 QVAIHPSGSYILTASKDGKMKILDL 260
+V + G + ++ DG + +LDL
Sbjct: 498 EVCWNARGDKVGASASDGSVCVLDL 522
>BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 101 bits (241), Expect = 2e-20
Identities = 67/294 (22%), Positives = 134/294 (45%), Gaps = 9/294 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + + G+ + + AH+ + +F D + I+T+S D
Sbjct: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + + FVGHT +S D ++ S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE---AVTQVAIHPSGSYI 246
+ + P+G + + + +L+D+R + +S H ++T VA SG +
Sbjct: 227 SDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS-HESIICSITSVAFSLSGRLL 285
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D ++ + LSGH+ V+ + + G ++ D + IW
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 71.3 bits (167), Expect = 2e-11
Identities = 45/160 (28%), Positives = 73/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKY 77
GH +L +P+ + + D S LWD+R GT R F GH+ + + F +G+
Sbjct: 182 GHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQ-TFTGHESDINAICFFPNGEA 240
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQ--TVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ + S D + R++ F S ++ SV FS G + DD +W +
Sbjct: 241 ICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K + + GH N V C ++ DG +A+ S D K+WN
Sbjct: 301 KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 62.1 bits (144), Expect = 9e-09
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN + I T S D S L+DLR F H+ + +
Sbjct: 215 EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICF-SHESIICSI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W + G+ H V + ++DG + T S D
Sbjct: 274 TSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 101 bits (241), Expect = 2e-20
Identities = 67/294 (22%), Positives = 134/294 (45%), Gaps = 9/294 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + + G+ + + AH+ + +F D + I+T+S D
Sbjct: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + + FVGHT +S D ++ S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE---AVTQVAIHPSGSYI 246
+ + P+G + + + +L+D+R + +S H ++T VA SG +
Sbjct: 227 SDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS-HESIICSITSVAFSLSGRLL 285
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D ++ + LSGH+ V+ + + G ++ D + IW
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 71.3 bits (167), Expect = 2e-11
Identities = 45/160 (28%), Positives = 73/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKY 77
GH +L +P+ + + D S LWD+R GT R F GH+ + + F +G+
Sbjct: 182 GHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQ-TFTGHESDINAICFFPNGEA 240
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQ--TVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ + S D + R++ F S ++ SV FS G + DD +W +
Sbjct: 241 ICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K + + GH N V C ++ DG +A+ S D K+WN
Sbjct: 301 KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 62.1 bits (144), Expect = 9e-09
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN + I T S D S L+DLR F H+ + +
Sbjct: 215 EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICF-SHESIICSI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W + G+ H V + ++DG + T S D
Sbjct: 274 TSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 101 bits (241), Expect = 2e-20
Identities = 67/294 (22%), Positives = 134/294 (45%), Gaps = 9/294 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + + G+ + + AH+ + +F D + I+T+S D
Sbjct: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + + FVGHT +S D ++ S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE---AVTQVAIHPSGSYI 246
+ + P+G + + + +L+D+R + +S H ++T VA SG +
Sbjct: 227 SDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS-HESIICSITSVAFSLSGRLL 285
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D ++ + LSGH+ V+ + + G ++ D + IW
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 71.3 bits (167), Expect = 2e-11
Identities = 45/160 (28%), Positives = 73/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKY 77
GH +L +P+ + + D S LWD+R GT R F GH+ + + F +G+
Sbjct: 182 GHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQ-TFTGHESDINAICFFPNGEA 240
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQ--TVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ + S D + R++ F S ++ SV FS G + DD +W +
Sbjct: 241 ICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFAGYDDFNCNVWDSM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K + + GH N V C ++ DG +A+ S D K+WN
Sbjct: 301 KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 62.1 bits (144), Expect = 9e-09
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN + I T S D S L+DLR F H+ + +
Sbjct: 215 EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICF-SHESIICSI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W + G+ H V + ++DG + T S D
Sbjct: 274 TSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa protein
protein.
Length = 521
Score = 101 bits (241), Expect = 2e-20
Identities = 68/291 (23%), Positives = 121/291 (41%), Gaps = 9/291 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY- 77
G I+ +++PN + +AT+ LW + + +GH+ V + F
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 78 -------MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVK 130
+AS + D +V++W + H+ V V + G + T D+ +
Sbjct: 288 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
LW + I GH+ V DGS+ + D ++W+L +G CI +D
Sbjct: 348 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEDHLK 407
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP-SGSYILTA 249
+ + P+G ++A + K++D+R V H VT V P G+++LT
Sbjct: 408 EIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPPHQNLVTGVKFEPIHGNFLLTG 467
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D KI P+ TL+GH G V ++ S G ++ D+ +W
Sbjct: 468 AYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATYSYDRTFKLW 518
Score = 74.9 bits (176), Expect = 1e-12
Identities = 47/202 (23%), Positives = 84/202 (41%), Gaps = 3/202 (1%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++GH + + ++P+ + + T+ D S LWDL +GH V D+ F G
Sbjct: 318 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 377
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ D R+W TG MF + H + + + FS +G I T S D K+W
Sbjct: 378 LAGTGGLDAFGRVW-DLRTGRCIMFLEDHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR 436
Query: 136 KHKFISSFVGHTNWVRCARMSN-DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
+ + + + H N V + G+ + + + D + K+W + T +G +
Sbjct: 437 QRRCVYTIPPHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMG 496
Query: 195 LAWHPSGCYVAVATSHGNVKLY 216
L G +A + KL+
Sbjct: 497 LDISSDGQLIATYSYDRTFKLW 518
Score = 74.1 bits (174), Expect = 2e-12
Identities = 44/162 (27%), Positives = 77/162 (47%), Gaps = 3/162 (1%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRF-QGHDEAVMDVTFSSSGK 76
+GH + + ++ + T LD +WDLR T R F + H + + + FS +G
Sbjct: 361 EGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLR-TGRCIMFLEDHLKEIYGINFSPNGY 419
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSS-DGSKIITASDDKVVKLWSTH 135
++A+ S D T ++W H V V+F G+ ++T + D K+W+
Sbjct: 420 HIATGSGDNTCKVWDLRQRRCVYTIPPHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHP 479
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
+ + GH V +S+DG +IA+ S D++ KLW L+
Sbjct: 480 GWSPLKTLAGHEGKVMGLDISSDGQLIATYSYDRTFKLWMLE 521
Score = 49.6 bits (113), Expect = 5e-05
Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 14/170 (8%)
Query: 142 SFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWH 198
S +G + S + ++A+ KLW++ +HT L+GH + + +H
Sbjct: 225 SQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHT---LRGHNTNVGAIVFH 281
Query: 199 PSGCY--------VAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
P +A + G+VKL+ + + V H V +V HPSG ++ T
Sbjct: 282 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 341
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D ++ DL I GH+ V + F G + G D +W
Sbjct: 342 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 391
>Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-binding
protein beta3 subunit protein.
Length = 340
Score = 100 bits (240), Expect = 2e-20
Identities = 67/294 (22%), Positives = 133/294 (45%), Gaps = 9/294 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + + G+ + + AH+ + +F D + I+T+S D
Sbjct: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + + FVGHT +S D ++ S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE---AVTQVAIHPSGSYI 246
+ + P+G + + + +L+D+R + +S H +T VA SG +
Sbjct: 227 SDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS-HESIICGITSVAFSLSGRLL 285
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D ++ + LSGH+ V+ + + G ++ D + IW
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 70.5 bits (165), Expect = 3e-11
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKY 77
GH +L +P+ + + D S LWD+R GT R F GH+ + + F +G+
Sbjct: 182 GHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQ-TFTGHESDINAICFFPNGEA 240
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQT--VRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ + S D + R++ F S + SV FS G + DD +W +
Sbjct: 241 ICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K + + GH N V C ++ DG +A+ S D K+WN
Sbjct: 301 KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 61.7 bits (143), Expect = 1e-08
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN + I T S D S L+DLR F H+ + +
Sbjct: 215 EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICF-SHESIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W + G+ H V + ++DG + T S D
Sbjct: 274 TSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain
protein.
Length = 340
Score = 100 bits (240), Expect = 2e-20
Identities = 67/294 (22%), Positives = 133/294 (45%), Gaps = 9/294 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + + G+ + + AH+ + +F D + I+T+S D
Sbjct: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + + FVGHT +S D ++ S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE---AVTQVAIHPSGSYI 246
+ + P+G + + + +L+D+R + +S H +T VA SG +
Sbjct: 227 SDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS-HESIICGITSVAFSLSGRLL 285
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D ++ + LSGH+ V+ + + G ++ D + IW
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 70.5 bits (165), Expect = 3e-11
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKY 77
GH +L +P+ + + D S LWD+R GT R F GH+ + + F +G+
Sbjct: 182 GHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQ-TFTGHESDINAICFFPNGEA 240
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQT--VRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ + S D + R++ F S + SV FS G + DD +W +
Sbjct: 241 ICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K + + GH N V C ++ DG +A+ S D K+WN
Sbjct: 301 KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 61.7 bits (143), Expect = 1e-08
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN + I T S D S L+DLR F H+ + +
Sbjct: 215 EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICF-SHESIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W + G+ H V + ++DG + T S D
Sbjct: 274 TSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein.
Length = 340
Score = 100 bits (240), Expect = 2e-20
Identities = 67/294 (22%), Positives = 133/294 (45%), Gaps = 9/294 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + + G+ + + AH+ + +F D + I+T+S D
Sbjct: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + + FVGHT +S D ++ S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE---AVTQVAIHPSGSYI 246
+ + P+G + + + +L+D+R + +S H +T VA SG +
Sbjct: 227 SDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS-HESIICGITSVAFSLSGRLL 285
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D ++ + LSGH+ V+ + + G ++ D + IW
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 70.5 bits (165), Expect = 3e-11
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKY 77
GH +L +P+ + + D S LWD+R GT R F GH+ + + F +G+
Sbjct: 182 GHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQ-TFTGHESDINAICFFPNGEA 240
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQT--VRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ + S D + R++ F S + SV FS G + DD +W +
Sbjct: 241 ICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K + + GH N V C ++ DG +A+ S D K+WN
Sbjct: 301 KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 61.7 bits (143), Expect = 1e-08
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN + I T S D S L+DLR F H+ + +
Sbjct: 215 EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICF-SHESIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W + G+ H V + ++DG + T S D
Sbjct: 274 TSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 100 bits (240), Expect = 2e-20
Identities = 67/294 (22%), Positives = 133/294 (45%), Gaps = 9/294 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + + G+ + + AH+ + +F D + I+T+S D
Sbjct: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + + FVGHT +S D ++ S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE---AVTQVAIHPSGSYI 246
+ + P+G + + + +L+D+R + +S H +T VA SG +
Sbjct: 227 SDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS-HESIICGITSVAFSLSGRLL 285
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D ++ + LSGH+ V+ + + G ++ D + IW
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 70.5 bits (165), Expect = 3e-11
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKY 77
GH +L +P+ + + D S LWD+R GT R F GH+ + + F +G+
Sbjct: 182 GHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQ-TFTGHESDINAICFFPNGEA 240
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQT--VRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ + S D + R++ F S + SV FS G + DD +W +
Sbjct: 241 ICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K + + GH N V C ++ DG +A+ S D K+WN
Sbjct: 301 KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 61.7 bits (143), Expect = 1e-08
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN + I T S D S L+DLR F H+ + +
Sbjct: 215 EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICF-SHESIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W + G+ H V + ++DG + T S D
Sbjct: 274 TSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide binding
protein beta 3 protein.
Length = 340
Score = 100 bits (240), Expect = 2e-20
Identities = 67/294 (22%), Positives = 133/294 (45%), Gaps = 9/294 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 48 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP 107
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + + G+ + + AH+ + +F D + I+T+S D
Sbjct: 108 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTC 166
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + + FVGHT +S D ++ S + D S KLW++ G C T+ +
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE 226
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE---AVTQVAIHPSGSYI 246
+ + P+G + + + +L+D+R + +S H +T VA SG +
Sbjct: 227 SDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS-HESIICGITSVAFSLSGRLL 285
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D ++ + LSGH+ V+ + + G ++ D + IW
Sbjct: 286 FAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 70.5 bits (165), Expect = 3e-11
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKY 77
GH +L +P+ + + D S LWD+R GT R F GH+ + + F +G+
Sbjct: 182 GHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQ-TFTGHESDINAICFFPNGEA 240
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQT--VRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ + S D + R++ F S + SV FS G + DD +W +
Sbjct: 241 ICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSM 300
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K + + GH N V C ++ DG +A+ S D K+WN
Sbjct: 301 KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
Score = 61.7 bits (143), Expect = 1e-08
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN + I T S D S L+DLR F H+ + +
Sbjct: 215 EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICF-SHESIICGI 273
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W + G+ H V + ++DG + T S D
Sbjct: 274 TSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWD 333
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 334 SFLKIWN 340
>AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-binding
protein, beta-3 subunit variant protein.
Length = 327
Score = 100 bits (240), Expect = 2e-20
Identities = 67/294 (22%), Positives = 133/294 (45%), Gaps = 9/294 (3%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
++ L+GH I A+++ + + + ++S D +++WD T + + VM ++
Sbjct: 35 RRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAP 94
Query: 74 SGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKIITASDDKVV 129
SG ++A D I+ + + G+ + + AH+ + +F D + I+T+S D
Sbjct: 95 SGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTC 153
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
LW + + FVGHT +S D ++ S + D S KLW++ G C T+ +
Sbjct: 154 ALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE 213
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE---AVTQVAIHPSGSYI 246
+ + P+G + + + +L+D+R + +S H +T VA SG +
Sbjct: 214 SDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFS-HESIICGITSVAFSLSGRLL 272
Query: 247 LTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D + D ++ + LSGH+ V+ + + G ++ D + IW
Sbjct: 273 FAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 326
Score = 70.5 bits (165), Expect = 3e-11
Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKY 77
GH +L +P+ + + D S LWD+R GT R F GH+ + + F +G+
Sbjct: 169 GHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQ-TFTGHESDINAICFFPNGEA 227
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQT--VRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ + S D + R++ F S + SV FS G + DD +W +
Sbjct: 228 ICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSM 287
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K + + GH N V C ++ DG +A+ S D K+WN
Sbjct: 288 KSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 327
Score = 61.7 bits (143), Expect = 1e-08
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN + I T S D S L+DLR F H+ + +
Sbjct: 202 EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICF-SHESIICGI 260
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W + G+ H V + ++DG + T S D
Sbjct: 261 TSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWD 320
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 321 SFLKIWN 327
>CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein.
Length = 521
Score = 99 bits (238), Expect = 4e-20
Identities = 67/291 (23%), Positives = 120/291 (41%), Gaps = 9/291 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY- 77
G I+ +++PN + +AT+ LW + + +GH+ V + F
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 78 -------MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVK 130
+AS + D +V++W + H+ V V + G + T D+ +
Sbjct: 288 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
LW + I GH+ V DGS+ + D ++W+L +G CI +
Sbjct: 348 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 407
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP-SGSYILTA 249
+ + P+G ++A + K++D+R V H VT V P G+++LT
Sbjct: 408 EIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTG 467
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D KI P+ TL+GH G V ++ S G ++ D+ +W
Sbjct: 468 AYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 83.0 bits (196), Expect = 5e-15
Identities = 47/162 (29%), Positives = 79/162 (48%), Gaps = 3/162 (1%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRF-QGHDEAVMDVTFSSSGK 76
+GH + + ++ + T LD +WDLR T R F +GH + + + FS +G
Sbjct: 361 EGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLR-TGRCIMFLEGHLKEIYGINFSPNGY 419
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSS-DGSKIITASDDKVVKLWSTH 135
++A+ S D T ++W AH V V+F G+ ++T + D K+W+
Sbjct: 420 HIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHP 479
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
+ + GH V +S+DG +IA+CS D++ KLW D
Sbjct: 480 GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAD 521
Score = 79.8 bits (188), Expect = 4e-14
Identities = 60/260 (23%), Positives = 105/260 (40%), Gaps = 9/260 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPN--------DQQIATSSLDNSVLLWDLRGTMRSYR 58
+ P+ L L+GH + A+ ++P D +A+ + D SV LW L
Sbjct: 258 SVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVAD 317
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
+GH V V + SG+++ + D++ R+W + HS V + F DGS
Sbjct: 318 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 377
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
T D ++W + I GH + S +G IA+ S D + K+W+L
Sbjct: 378 LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQ 437
Query: 179 GECIHTYKDLKGHGLHLAWHP-SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
C++T + + + P G ++ K++ + ++ + H V +
Sbjct: 438 RRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 497
Query: 238 AIHPSGSYILTASKDGKMKI 257
I G I T S D K+
Sbjct: 498 DISSDGQLIATCSYDRTFKL 517
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/202 (23%), Positives = 84/202 (41%), Gaps = 3/202 (1%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++GH + + ++P+ + + T+ D S LWDL +GH V D+ F G
Sbjct: 318 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 377
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ D R+W TG MF + H + + + FS +G I T S D K+W
Sbjct: 378 LAGTGGLDAFGRVW-DLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR 436
Query: 136 KHKFISSFVGHTNWVRCARMSN-DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
+ + + + H N V + G+ + + + D + K+W + T +G +
Sbjct: 437 QRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMG 496
Query: 195 LAWHPSGCYVAVATSHGNVKLY 216
L G +A + KL+
Sbjct: 497 LDISSDGQLIATCSYDRTFKLW 518
Score = 49.6 bits (113), Expect = 5e-05
Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 14/170 (8%)
Query: 142 SFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWH 198
S +G + S + ++A+ KLW++ +HT L+GH + + +H
Sbjct: 225 SQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHT---LRGHNTNVGAIVFH 281
Query: 199 PSGCY--------VAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
P +A + G+VKL+ + + V H V +V HPSG ++ T
Sbjct: 282 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 341
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D ++ DL I GH+ V + F G + G D +W
Sbjct: 342 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 391
>BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 99 bits (238), Expect = 4e-20
Identities = 67/291 (23%), Positives = 120/291 (41%), Gaps = 9/291 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY- 77
G I+ +++PN + +AT+ LW + + +GH+ V + F
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 78 -------MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVK 130
+AS + D +V++W + H+ V V + G + T D+ +
Sbjct: 288 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
LW + I GH+ V DGS+ + D ++W+L +G CI +
Sbjct: 348 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 407
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP-SGSYILTA 249
+ + P+G ++A + K++D+R V H VT V P G+++LT
Sbjct: 408 EIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTG 467
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D KI P+ TL+GH G V ++ S G ++ D+ +W
Sbjct: 468 AYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 79.8 bits (188), Expect = 4e-14
Identities = 60/260 (23%), Positives = 105/260 (40%), Gaps = 9/260 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPN--------DQQIATSSLDNSVLLWDLRGTMRSYR 58
+ P+ L L+GH + A+ ++P D +A+ + D SV LW L
Sbjct: 258 SVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVAD 317
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
+GH V V + SG+++ + D++ R+W + HS V + F DGS
Sbjct: 318 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 377
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
T D ++W + I GH + S +G IA+ S D + K+W+L
Sbjct: 378 LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQ 437
Query: 179 GECIHTYKDLKGHGLHLAWHP-SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
C++T + + + P G ++ K++ + ++ + H V +
Sbjct: 438 RRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 497
Query: 238 AIHPSGSYILTASKDGKMKI 257
I G I T S D K+
Sbjct: 498 DISSDGQLIATCSYDRTFKL 517
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/202 (23%), Positives = 84/202 (41%), Gaps = 3/202 (1%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++GH + + ++P+ + + T+ D S LWDL +GH V D+ F G
Sbjct: 318 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 377
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ D R+W TG MF + H + + + FS +G I T S D K+W
Sbjct: 378 LAGTGGLDAFGRVW-DLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR 436
Query: 136 KHKFISSFVGHTNWVRCARMSN-DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
+ + + + H N V + G+ + + + D + K+W + T +G +
Sbjct: 437 QRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMG 496
Query: 195 LAWHPSGCYVAVATSHGNVKLY 216
L G +A + KL+
Sbjct: 497 LDISSDGQLIATCSYDRTFKLW 518
Score = 49.6 bits (113), Expect = 5e-05
Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 14/170 (8%)
Query: 142 SFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWH 198
S +G + S + ++A+ KLW++ +HT L+GH + + +H
Sbjct: 225 SQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHT---LRGHNTNVGAIVFH 281
Query: 199 PSGCY--------VAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
P +A + G+VKL+ + + V H V +V HPSG ++ T
Sbjct: 282 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 341
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D ++ DL I GH+ V + F G + G D +W
Sbjct: 342 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 391
Score = 47.6 bits (108), Expect = 2e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 17 LKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
+ H+N +T + + P + + T + DN+ +W G GH+ VM + SS G
Sbjct: 444 IPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDG 503
Query: 76 KYMASASRDKTVRIWV 91
+ +A+ S D+T ++W+
Sbjct: 504 QLIATCSYDRTFKLWM 519
>BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 99 bits (238), Expect = 4e-20
Identities = 67/291 (23%), Positives = 120/291 (41%), Gaps = 9/291 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY- 77
G I+ +++PN + +AT+ LW + + +GH+ V + F
Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 78 -------MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVK 130
+AS + D +V++W + H+ V V + G + T D+ +
Sbjct: 289 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 348
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
LW + I GH+ V DGS+ + D ++W+L +G CI +
Sbjct: 349 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 408
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP-SGSYILTA 249
+ + P+G ++A + K++D+R V H VT V P G+++LT
Sbjct: 409 EIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTG 468
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D KI P+ TL+GH G V ++ S G ++ D+ +W
Sbjct: 469 AYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 79.8 bits (188), Expect = 4e-14
Identities = 60/260 (23%), Positives = 105/260 (40%), Gaps = 9/260 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPN--------DQQIATSSLDNSVLLWDLRGTMRSYR 58
+ P+ L L+GH + A+ ++P D +A+ + D SV LW L
Sbjct: 259 SVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVAD 318
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
+GH V V + SG+++ + D++ R+W + HS V + F DGS
Sbjct: 319 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 378
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
T D ++W + I GH + S +G IA+ S D + K+W+L
Sbjct: 379 LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQ 438
Query: 179 GECIHTYKDLKGHGLHLAWHP-SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
C++T + + + P G ++ K++ + ++ + H V +
Sbjct: 439 RRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 498
Query: 238 AIHPSGSYILTASKDGKMKI 257
I G I T S D K+
Sbjct: 499 DISSDGQLIATCSYDRTFKL 518
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/202 (23%), Positives = 84/202 (41%), Gaps = 3/202 (1%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++GH + + ++P+ + + T+ D S LWDL +GH V D+ F G
Sbjct: 319 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 378
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ D R+W TG MF + H + + + FS +G I T S D K+W
Sbjct: 379 LAGTGGLDAFGRVW-DLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR 437
Query: 136 KHKFISSFVGHTNWVRCARMSN-DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
+ + + + H N V + G+ + + + D + K+W + T +G +
Sbjct: 438 QRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMG 497
Query: 195 LAWHPSGCYVAVATSHGNVKLY 216
L G +A + KL+
Sbjct: 498 LDISSDGQLIATCSYDRTFKLW 519
Score = 49.6 bits (113), Expect = 5e-05
Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 14/170 (8%)
Query: 142 SFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWH 198
S +G + S + ++A+ KLW++ +HT L+GH + + +H
Sbjct: 226 SQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHT---LRGHNTNVGAIVFH 282
Query: 199 PSGCY--------VAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
P +A + G+VKL+ + + V H V +V HPSG ++ T
Sbjct: 283 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 342
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D ++ DL I GH+ V + F G + G D +W
Sbjct: 343 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 392
Score = 47.6 bits (108), Expect = 2e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 17 LKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
+ H+N +T + + P + + T + DN+ +W G GH+ VM + SS G
Sbjct: 445 IPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDG 504
Query: 76 KYMASASRDKTVRIWV 91
+ +A+ S D+T ++W+
Sbjct: 505 QLIATCSYDRTFKLWM 520
>AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6
snRNP-specific spliceosomal protein protein.
Length = 521
Score = 99 bits (238), Expect = 4e-20
Identities = 67/291 (23%), Positives = 120/291 (41%), Gaps = 9/291 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY- 77
G I+ +++PN + +AT+ LW + + +GH+ V + F
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 78 -------MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVK 130
+AS + D +V++W + H+ V V + G + T D+ +
Sbjct: 288 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
LW + I GH+ V DGS+ + D ++W+L +G CI +
Sbjct: 348 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 407
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP-SGSYILTA 249
+ + P+G ++A + K++D+R V H VT V P G+++LT
Sbjct: 408 EIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTG 467
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D KI P+ TL+GH G V ++ S G ++ D+ +W
Sbjct: 468 AYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 79.8 bits (188), Expect = 4e-14
Identities = 60/260 (23%), Positives = 105/260 (40%), Gaps = 9/260 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPN--------DQQIATSSLDNSVLLWDLRGTMRSYR 58
+ P+ L L+GH + A+ ++P D +A+ + D SV LW L
Sbjct: 258 SVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVAD 317
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
+GH V V + SG+++ + D++ R+W + HS V + F DGS
Sbjct: 318 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 377
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
T D ++W + I GH + S +G IA+ S D + K+W+L
Sbjct: 378 LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQ 437
Query: 179 GECIHTYKDLKGHGLHLAWHP-SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
C++T + + + P G ++ K++ + ++ + H V +
Sbjct: 438 RRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 497
Query: 238 AIHPSGSYILTASKDGKMKI 257
I G I T S D K+
Sbjct: 498 DISSDGQLIATCSYDRTFKL 517
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/202 (23%), Positives = 84/202 (41%), Gaps = 3/202 (1%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++GH + + ++P+ + + T+ D S LWDL +GH V D+ F G
Sbjct: 318 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 377
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ D R+W TG MF + H + + + FS +G I T S D K+W
Sbjct: 378 LAGTGGLDAFGRVW-DLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR 436
Query: 136 KHKFISSFVGHTNWVRCARMSN-DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
+ + + + H N V + G+ + + + D + K+W + T +G +
Sbjct: 437 QRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMG 496
Query: 195 LAWHPSGCYVAVATSHGNVKLY 216
L G +A + KL+
Sbjct: 497 LDISSDGQLIATCSYDRTFKLW 518
Score = 49.6 bits (113), Expect = 5e-05
Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 14/170 (8%)
Query: 142 SFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWH 198
S +G + S + ++A+ KLW++ +HT L+GH + + +H
Sbjct: 225 SQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHT---LRGHNTNVGAIVFH 281
Query: 199 PSGCY--------VAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
P +A + G+VKL+ + + V H V +V HPSG ++ T
Sbjct: 282 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 341
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D ++ DL I GH+ V + F G + G D +W
Sbjct: 342 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 391
Score = 47.6 bits (108), Expect = 2e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 17 LKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
+ H+N +T + + P + + T + DN+ +W G GH+ VM + SS G
Sbjct: 444 IPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDG 503
Query: 76 KYMASASRDKTVRIWV 91
+ +A+ S D+T ++W+
Sbjct: 504 QLIATCSYDRTFKLWM 519
>AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 99 bits (238), Expect = 4e-20
Identities = 67/291 (23%), Positives = 120/291 (41%), Gaps = 9/291 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY- 77
G I+ +++PN + +AT+ LW + + +GH+ V + F
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 78 -------MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVK 130
+AS + D +V++W + H+ V V + G + T D+ +
Sbjct: 288 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
LW + I GH+ V DGS+ + D ++W+L +G CI +
Sbjct: 348 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 407
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP-SGSYILTA 249
+ + P+G ++A + K++D+R V H VT V P G+++LT
Sbjct: 408 EIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTG 467
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D KI P+ TL+GH G V ++ S G ++ D+ +W
Sbjct: 468 AYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 79.8 bits (188), Expect = 4e-14
Identities = 60/260 (23%), Positives = 105/260 (40%), Gaps = 9/260 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPN--------DQQIATSSLDNSVLLWDLRGTMRSYR 58
+ P+ L L+GH + A+ ++P D +A+ + D SV LW L
Sbjct: 258 SVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVAD 317
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
+GH V V + SG+++ + D++ R+W + HS V + F DGS
Sbjct: 318 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 377
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
T D ++W + I GH + S +G IA+ S D + K+W+L
Sbjct: 378 LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQ 437
Query: 179 GECIHTYKDLKGHGLHLAWHP-SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
C++T + + + P G ++ K++ + ++ + H V +
Sbjct: 438 RRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 497
Query: 238 AIHPSGSYILTASKDGKMKI 257
I G I T S D K+
Sbjct: 498 DISSDGQLIATCSYDRTFKL 517
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/202 (23%), Positives = 84/202 (41%), Gaps = 3/202 (1%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++GH + + ++P+ + + T+ D S LWDL +GH V D+ F G
Sbjct: 318 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 377
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ D R+W TG MF + H + + + FS +G I T S D K+W
Sbjct: 378 LAGTGGLDAFGRVW-DLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR 436
Query: 136 KHKFISSFVGHTNWVRCARMSN-DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
+ + + + H N V + G+ + + + D + K+W + T +G +
Sbjct: 437 QRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMG 496
Query: 195 LAWHPSGCYVAVATSHGNVKLY 216
L G +A + KL+
Sbjct: 497 LDISSDGQLIATCSYDRTFKLW 518
Score = 49.6 bits (113), Expect = 5e-05
Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 14/170 (8%)
Query: 142 SFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWH 198
S +G + S + ++A+ KLW++ +HT L+GH + + +H
Sbjct: 225 SQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHT---LRGHNTNVGAIVFH 281
Query: 199 PSGCY--------VAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
P +A + G+VKL+ + + V H V +V HPSG ++ T
Sbjct: 282 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 341
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D ++ DL I GH+ V + F G + G D +W
Sbjct: 342 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 391
Score = 47.6 bits (108), Expect = 2e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 17 LKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
+ H+N +T + + P + + T + DN+ +W G GH+ VM + SS G
Sbjct: 444 IPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDG 503
Query: 76 KYMASASRDKTVRIWV 91
+ +A+ S D+T ++W+
Sbjct: 504 QLIATCSYDRTFKLWM 519
>AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 99 bits (238), Expect = 4e-20
Identities = 67/291 (23%), Positives = 120/291 (41%), Gaps = 9/291 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY- 77
G I+ +++PN + +AT+ LW + + +GH+ V + F
Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 78 -------MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVK 130
+AS + D +V++W + H+ V V + G + T D+ +
Sbjct: 289 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 348
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
LW + I GH+ V DGS+ + D ++W+L +G CI +
Sbjct: 349 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 408
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP-SGSYILTA 249
+ + P+G ++A + K++D+R V H VT V P G+++LT
Sbjct: 409 EIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTG 468
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D KI P+ TL+GH G V ++ S G ++ D+ +W
Sbjct: 469 AYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 79.8 bits (188), Expect = 4e-14
Identities = 60/260 (23%), Positives = 105/260 (40%), Gaps = 9/260 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPN--------DQQIATSSLDNSVLLWDLRGTMRSYR 58
+ P+ L L+GH + A+ ++P D +A+ + D SV LW L
Sbjct: 259 SVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVAD 318
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
+GH V V + SG+++ + D++ R+W + HS V + F DGS
Sbjct: 319 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 378
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
T D ++W + I GH + S +G IA+ S D + K+W+L
Sbjct: 379 LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQ 438
Query: 179 GECIHTYKDLKGHGLHLAWHP-SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
C++T + + + P G ++ K++ + ++ + H V +
Sbjct: 439 RRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 498
Query: 238 AIHPSGSYILTASKDGKMKI 257
I G I T S D K+
Sbjct: 499 DISSDGQLIATCSYDRTFKL 518
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/202 (23%), Positives = 84/202 (41%), Gaps = 3/202 (1%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++GH + + ++P+ + + T+ D S LWDL +GH V D+ F G
Sbjct: 319 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 378
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ D R+W TG MF + H + + + FS +G I T S D K+W
Sbjct: 379 LAGTGGLDAFGRVW-DLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR 437
Query: 136 KHKFISSFVGHTNWVRCARMSN-DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
+ + + + H N V + G+ + + + D + K+W + T +G +
Sbjct: 438 QRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMG 497
Query: 195 LAWHPSGCYVAVATSHGNVKLY 216
L G +A + KL+
Sbjct: 498 LDISSDGQLIATCSYDRTFKLW 519
Score = 49.6 bits (113), Expect = 5e-05
Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 14/170 (8%)
Query: 142 SFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWH 198
S +G + S + ++A+ KLW++ +HT L+GH + + +H
Sbjct: 226 SQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHT---LRGHNTNVGAIVFH 282
Query: 199 PSGCY--------VAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
P +A + G+VKL+ + + V H V +V HPSG ++ T
Sbjct: 283 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 342
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D ++ DL I GH+ V + F G + G D +W
Sbjct: 343 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 392
Score = 47.6 bits (108), Expect = 2e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 17 LKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
+ H+N +T + + P + + T + DN+ +W G GH+ VM + SS G
Sbjct: 445 IPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDG 504
Query: 76 KYMASASRDKTVRIWV 91
+ +A+ S D+T ++W+
Sbjct: 505 QLIATCSYDRTFKLWM 520
>AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear
ribonucleoprotein hPrp4 protein.
Length = 522
Score = 99 bits (238), Expect = 4e-20
Identities = 67/291 (23%), Positives = 120/291 (41%), Gaps = 9/291 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY- 77
G I+ +++PN + +AT+ LW + + +GH+ V + F
Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 78 -------MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVK 130
+AS + D +V++W + H+ V V + G + T D+ +
Sbjct: 289 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 348
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
LW + I GH+ V DGS+ + D ++W+L +G CI +
Sbjct: 349 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 408
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP-SGSYILTA 249
+ + P+G ++A + K++D+R V H VT V P G+++LT
Sbjct: 409 EIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTG 468
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D KI P+ TL+GH G V ++ S G ++ D+ +W
Sbjct: 469 AYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 79.8 bits (188), Expect = 4e-14
Identities = 60/260 (23%), Positives = 105/260 (40%), Gaps = 9/260 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPN--------DQQIATSSLDNSVLLWDLRGTMRSYR 58
+ P+ L L+GH + A+ ++P D +A+ + D SV LW L
Sbjct: 259 SVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVAD 318
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
+GH V V + SG+++ + D++ R+W + HS V + F DGS
Sbjct: 319 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 378
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
T D ++W + I GH + S +G IA+ S D + K+W+L
Sbjct: 379 LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQ 438
Query: 179 GECIHTYKDLKGHGLHLAWHP-SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
C++T + + + P G ++ K++ + ++ + H V +
Sbjct: 439 RRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 498
Query: 238 AIHPSGSYILTASKDGKMKI 257
I G I T S D K+
Sbjct: 499 DISSDGQLIATCSYDRTFKL 518
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/202 (23%), Positives = 84/202 (41%), Gaps = 3/202 (1%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++GH + + ++P+ + + T+ D S LWDL +GH V D+ F G
Sbjct: 319 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 378
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ D R+W TG MF + H + + + FS +G I T S D K+W
Sbjct: 379 LAGTGGLDAFGRVW-DLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR 437
Query: 136 KHKFISSFVGHTNWVRCARMSN-DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
+ + + + H N V + G+ + + + D + K+W + T +G +
Sbjct: 438 QRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMG 497
Query: 195 LAWHPSGCYVAVATSHGNVKLY 216
L G +A + KL+
Sbjct: 498 LDISSDGQLIATCSYDRTFKLW 519
Score = 49.6 bits (113), Expect = 5e-05
Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 14/170 (8%)
Query: 142 SFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWH 198
S +G + S + ++A+ KLW++ +HT L+GH + + +H
Sbjct: 226 SQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHT---LRGHNTNVGAIVFH 282
Query: 199 PSGCY--------VAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
P +A + G+VKL+ + + V H V +V HPSG ++ T
Sbjct: 283 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 342
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D ++ DL I GH+ V + F G + G D +W
Sbjct: 343 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 392
Score = 47.6 bits (108), Expect = 2e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 17 LKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
+ H+N +T + + P + + T + DN+ +W G GH+ VM + SS G
Sbjct: 445 IPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDG 504
Query: 76 KYMASASRDKTVRIWV 91
+ +A+ S D+T ++W+
Sbjct: 505 QLIATCSYDRTFKLWM 520
>AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant
protein.
Length = 537
Score = 99 bits (238), Expect = 4e-20
Identities = 67/291 (23%), Positives = 120/291 (41%), Gaps = 9/291 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY- 77
G I+ +++PN + +AT+ LW + + +GH+ V + F
Sbjct: 244 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 303
Query: 78 -------MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVK 130
+AS + D +V++W + H+ V V + G + T D+ +
Sbjct: 304 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 363
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
LW + I GH+ V DGS+ + D ++W+L +G CI +
Sbjct: 364 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 423
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP-SGSYILTA 249
+ + P+G ++A + K++D+R V H VT V P G+++LT
Sbjct: 424 EIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTG 483
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D KI P+ TL+GH G V ++ S G ++ D+ +W
Sbjct: 484 AYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 534
Score = 79.8 bits (188), Expect = 4e-14
Identities = 60/260 (23%), Positives = 105/260 (40%), Gaps = 9/260 (3%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPN--------DQQIATSSLDNSVLLWDLRGTMRSYR 58
+ P+ L L+GH + A+ ++P D +A+ + D SV LW L
Sbjct: 274 SVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVAD 333
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
+GH V V + SG+++ + D++ R+W + HS V + F DGS
Sbjct: 334 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 393
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
T D ++W + I GH + S +G IA+ S D + K+W+L
Sbjct: 394 LAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQ 453
Query: 179 GECIHTYKDLKGHGLHLAWHP-SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
C++T + + + P G ++ K++ + ++ + H V +
Sbjct: 454 RRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 513
Query: 238 AIHPSGSYILTASKDGKMKI 257
I G I T S D K+
Sbjct: 514 DISSDGQLIATCSYDRTFKL 533
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/202 (23%), Positives = 84/202 (41%), Gaps = 3/202 (1%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++GH + + ++P+ + + T+ D S LWDL +GH V D+ F G
Sbjct: 334 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 393
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ D R+W TG MF + H + + + FS +G I T S D K+W
Sbjct: 394 LAGTGGLDAFGRVW-DLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR 452
Query: 136 KHKFISSFVGHTNWVRCARMSN-DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
+ + + + H N V + G+ + + + D + K+W + T +G +
Sbjct: 453 QRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMG 512
Query: 195 LAWHPSGCYVAVATSHGNVKLY 216
L G +A + KL+
Sbjct: 513 LDISSDGQLIATCSYDRTFKLW 534
Score = 49.6 bits (113), Expect = 5e-05
Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 14/170 (8%)
Query: 142 SFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWH 198
S +G + S + ++A+ KLW++ +HT L+GH + + +H
Sbjct: 241 SQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHT---LRGHNTNVGAIVFH 297
Query: 199 PSGCY--------VAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
P +A + G+VKL+ + + V H V +V HPSG ++ T
Sbjct: 298 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 357
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
D ++ DL I GH+ V + F G + G D +W
Sbjct: 358 YDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 407
Score = 47.6 bits (108), Expect = 2e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 17 LKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
+ H+N +T + + P + + T + DN+ +W G GH+ VM + SS G
Sbjct: 460 IPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDG 519
Query: 76 KYMASASRDKTVRIWV 91
+ +A+ S D+T ++W+
Sbjct: 520 QLIATCSYDRTFKLWM 535
>AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 99.5 bits (237), Expect = 5e-20
Identities = 67/256 (26%), Positives = 120/256 (46%), Gaps = 16/256 (6%)
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H +AV FS G+ +AS DKT++++ KAH V FS+D I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDSG 179
T S DK VK+W++ + + ++ H+ V C +N ++A+ S D KLW+L+
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI------RTHNLVQYYSIHNEA 233
EC +T H + P +A ++ G +KL+D ++ N+ Q++ +
Sbjct: 734 ECRNTMFGHTNSANHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 793
Query: 234 VTQVAI-------HPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD 286
+ + G+ I+ A+K+ K+ + + + GH V+ V FSP G
Sbjct: 794 QEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGS 852
Query: 287 TFSSAGDDKLVFIWKT 302
+F ++ DD+ + +W+T
Sbjct: 853 SFLTSSDDQTIRLWET 868
Score = 87.0 bits (206), Expect = 3e-16
Identities = 61/256 (23%), Positives = 118/256 (46%), Gaps = 16/256 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 670
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN R S D ++ASCS D + KLW+ S + I+
Sbjct: 731 NQKECRNTMFGHTNSANHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 790
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+D++ +W G + VA + + L++ + + V H V V P
Sbjct: 791 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 242 SGSYILTASKDGKMKI 257
GS LT+S D +++
Sbjct: 850 DGSSFLTSSDDQTIRL 865
Score = 81.4 bits (192), Expect = 1e-14
Identities = 67/278 (24%), Positives = 116/278 (41%), Gaps = 19/278 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+AT S D + LWDL GH + FS K +AS S D T+++W T
Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGHTNSANHCRFSPDDKLLASCSADGTLKLWDATSA 775
Query: 96 GSTGMFKAHS-------------QTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
V+ +S+DG++I+ A+ +K+ LW+T ++
Sbjct: 776 NERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVAD 834
Query: 143 FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGC 202
GH +WV S DGS + SDD++ +LW C ++ LK + + + +
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNSAVMLK-QEVDVVFQENEV 892
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
V ++L + RT + Y + V+ + P YI ++G ++IL+L+
Sbjct: 893 MVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 263 GHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ H V + F+ T S+ DD + +W
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 987
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 2/160 (1%)
Query: 102 KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
+ H+ V FS DG +I + DK ++++ + + H + V C S D
Sbjct: 612 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN--VKLYDIR 219
IA+CS DK K+WN +GE +HTY + + S ++ +AT + +KL+D+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
H + P + + S DG +K+ D
Sbjct: 732 QKECRNTMFGHTNSANHCRFSPDDKLLASCSADGTLKLWD 771
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 927 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 986 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1161
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1162 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1203
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 893
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 894 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1005
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1006 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1065
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1066 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 59.7 bits (138), Expect = 5e-08
Identities = 55/233 (23%), Positives = 102/233 (43%), Gaps = 24/233 (10%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
K T E L ++K H++ + ++ +D+ IAT S+D V +W+ + + H E
Sbjct: 643 KAETGEKLL--EIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSE 700
Query: 65 AVMDVTFSSSGKY--MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
V F++S + +A+ S D +++W H+ + +FS D + +
Sbjct: 701 QVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSANHCRFSPDDKLLAS 760
Query: 123 ASDDKVVKLW---STHKHKFISSFVGHTNW----------VRCARMSNDGSIIASCSDDK 169
S D +KLW S ++ K I+ N V+C S DG+ I + +K
Sbjct: 761 CSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK 820
Query: 170 STKLWNLDSGECIHTYKDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIR 219
LWN DS + D +GH +H + + P G ++ ++L++ +
Sbjct: 821 -IFLWNTDSRSKV---ADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETK 869
>AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog
variant protein.
Length = 487
Score = 99.5 bits (237), Expect = 5e-20
Identities = 71/294 (24%), Positives = 130/294 (44%), Gaps = 14/294 (4%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L+GH A+ ++ ++P + +A+ S D +V WDL + +GH V+ +++S GK
Sbjct: 112 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 171
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKA-HSQTVRSVQF-----SSDGSKIITASDDKVVK 130
+AS ++ + +W P+ G A HS+ + + + + + + ++S D V+
Sbjct: 172 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 231
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
+W T + GHT V C R DG ++ S S D++ K+W G T L+G
Sbjct: 232 IWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRT---LQG 287
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQY-YSIHNEAVTQV-AIHPSGSYILT 248
HG + A+ T + +L + + A+++ + G L
Sbjct: 288 HGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGFLQELKERALSRYNLVRGQGPERLV 347
Query: 249 ASKDGKMKIL--DLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D L + P+ ++GH +N V FSP +SA DK + +W
Sbjct: 348 SGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLW 401
Score = 89.0 bits (211), Expect = 7e-17
Identities = 62/300 (20%), Positives = 127/300 (42%), Gaps = 8/300 (2%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWD-LRGTMRSYRFQGHDEAVMDVTF----- 71
KGH++ + ++ ++P+ +++A+ + +LLWD G GH + + +++
Sbjct: 155 KGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHA 214
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+ +Y+AS+S+D +VRIW T + H+Q+V +++ DG + +AS D+ +K+
Sbjct: 215 NPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKV 273
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W H + GH +WV +S D ++ + + D + K+
Sbjct: 274 WRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGFLQELKERALS 333
Query: 192 GLHLAWHPSGCYVAVATSHGNVKLYD-IRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
+L + + + L+ + + H + QV P + +AS
Sbjct: 334 RYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASAS 393
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSE 310
D +K+ D G + +L GH V + +S S D + +W L+ +
Sbjct: 394 FDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMD 453
Score = 86.6 bits (205), Expect = 4e-16
Identities = 76/296 (25%), Positives = 124/296 (41%), Gaps = 13/296 (4%)
Query: 15 KQLKGHKNAITALYY-----NPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
+ L GH IT L + NP + +A+SS D SV +WD GH ++V +
Sbjct: 195 RTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCL 254
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVV 129
+ G + SAS+D+T+++W + H V ++ S+D + A +
Sbjct: 255 RWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEA 313
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDG-SIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+ F+ R + G + S SDD + LW+ E +
Sbjct: 314 SVNPQDLQGFLQELKERA-LSRYNLVRGQGPERLVSGSDDFTLFLWS--PAEDKKPLTRM 370
Query: 189 KGHGL---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSY 245
GH + + P VA A+ ++KL+D RT + H AV Q+A
Sbjct: 371 TGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRL 430
Query: 246 ILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
+++ S D +K+ D+ L GH V AV++SP G +S G DK + IW+
Sbjct: 431 LVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 486
Score = 77.8 bits (183), Expect = 2e-13
Identities = 56/252 (22%), Positives = 105/252 (41%), Gaps = 3/252 (1%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAV 66
TT C ++ L GH ++T L + D + ++S D ++ +W + QGH V
Sbjct: 235 TTAGRC-ERILTGHTQSVTCLRWG-GDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWV 292
Query: 67 MDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
+ S+ A + + G K + + ++ ++++ SDD
Sbjct: 293 NTMALSTDYALRTGAFEPAEASVNPQDLQGFLQELKERALSRYNLVRGQGPERLVSGSDD 352
Query: 127 KVVKLWSTHKHKF-ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
+ LWS + K ++ GH + S D I+AS S DKS KLW+ +G+ + +
Sbjct: 353 FTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASL 412
Query: 186 KDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSY 245
+ +AW + +S +K++D++ L H + V V P G
Sbjct: 413 RGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQR 472
Query: 246 ILTASKDGKMKI 257
+ + KD ++I
Sbjct: 473 VASGGKDKCLRI 484
Score = 73.7 bits (173), Expect = 3e-12
Identities = 57/200 (28%), Positives = 90/200 (45%), Gaps = 11/200 (5%)
Query: 91 VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWV 150
V VT T + HS+ V SV FS G + + S D V+ W + GH +WV
Sbjct: 102 VRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWV 161
Query: 151 RCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG---LHLAWHP----SGC- 202
S DG +AS + LW+ +G+ + + L GH L+W P C
Sbjct: 162 LSISWSPDGKKLASGCKNGQILLWDPSTGKQVG--RTLAGHSKWITGLSWEPLHANPECR 219
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
YVA ++ G+V+++D + + H ++VT + G + +AS+D +K+ +
Sbjct: 220 YVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHD 278
Query: 263 GHPIFTLSGHNGPVNAVNFS 282
G TL GH VN + S
Sbjct: 279 GVLCRTLQGHGHWVNTMALS 298
Score = 67.7 bits (158), Expect = 2e-10
Identities = 46/169 (27%), Positives = 81/169 (47%), Gaps = 7/169 (4%)
Query: 141 SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPS 200
SS GH+ V S G +AS S D + + W+L + T K + L ++W P
Sbjct: 110 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 169
Query: 201 GCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQVA---IH--PSGSYILTASKDGK 254
G +A +G + L+D T V + + H++ +T ++ +H P Y+ ++SKDG
Sbjct: 170 GKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGS 229
Query: 255 MKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
++I D G L+GH V + + G + SA D+ + +W+ +
Sbjct: 230 VRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAH 277
>BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1
(Drosophila) protein.
Length = 485
Score = 98.7 bits (235), Expect = 9e-20
Identities = 71/294 (24%), Positives = 129/294 (43%), Gaps = 14/294 (4%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L+GH A+ ++ ++P + +A+ S D +V WDL + +GH V+ +++S GK
Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 169
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKA-HSQTVRSVQF-----SSDGSKIITASDDKVVK 130
+AS ++ + +W P+ G A HS+ + + + + + + ++S D V+
Sbjct: 170 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 229
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
+W T + GHT V C R DG ++ S S D++ K+W G T L+G
Sbjct: 230 IWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRT---LQG 285
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQV-AIHPSGSYILT 248
HG + A+ T + +L + A+++ + G L
Sbjct: 286 HGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLV 345
Query: 249 ASKDGKMKIL--DLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D L + P+ ++GH +N V FSP +SA DK + +W
Sbjct: 346 SGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLW 399
Score = 89.4 bits (212), Expect = 5e-17
Identities = 62/300 (20%), Positives = 127/300 (42%), Gaps = 8/300 (2%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWD-LRGTMRSYRFQGHDEAVMDVTF----- 71
KGH++ + ++ ++P+ +++A+ + +LLWD G GH + + +++
Sbjct: 153 KGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHA 212
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+ +Y+AS+S+D +VRIW T + H+Q+V +++ DG + +AS D+ +K+
Sbjct: 213 NPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKV 271
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W H + GH +WV +S D ++ + + D + K+
Sbjct: 272 WRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALS 331
Query: 192 GLHLAWHPSGCYVAVATSHGNVKLYD-IRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
+L + + + L+ + + H + QV P + +AS
Sbjct: 332 RYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASAS 391
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSE 310
D +K+ D G + +L GH V + +S S D + +W L+ +
Sbjct: 392 FDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMD 451
Score = 83.4 bits (197), Expect = 3e-15
Identities = 75/296 (25%), Positives = 123/296 (41%), Gaps = 13/296 (4%)
Query: 15 KQLKGHKNAITALYY-----NPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
+ L GH IT L + NP + +A+SS D SV +WD GH ++V +
Sbjct: 193 RTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCL 252
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVV 129
+ G + SAS+D+T+++W + H V ++ S+D + A +
Sbjct: 253 RWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEA 311
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDG-SIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+ + R + G + S SDD + LW+ E +
Sbjct: 312 SVNPQDLQGSLQELKERA-LSRYNLVRGQGPERLVSGSDDFTLFLWS--PAEDKKPLTRM 368
Query: 189 KGHGL---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSY 245
GH + + P VA A+ ++KL+D RT + H AV Q+A
Sbjct: 369 TGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRL 428
Query: 246 ILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
+++ S D +K+ D+ L GH V AV++SP G +S G DK + IW+
Sbjct: 429 LVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 484
Score = 80.2 bits (189), Expect = 3e-14
Identities = 57/252 (22%), Positives = 106/252 (42%), Gaps = 3/252 (1%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAV 66
TT C ++ L GH ++T L + D + ++S D ++ +W + QGH V
Sbjct: 233 TTAGRC-ERILTGHTQSVTCLRWG-GDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWV 290
Query: 67 MDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
+ S+ A + + GS K + + ++ ++++ SDD
Sbjct: 291 NTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDD 350
Query: 127 KVVKLWSTHKHKF-ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
+ LWS + K ++ GH + S D I+AS S DKS KLW+ +G+ + +
Sbjct: 351 FTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASL 410
Query: 186 KDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSY 245
+ +AW + +S +K++D++ L H + V V P G
Sbjct: 411 RGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQR 470
Query: 246 ILTASKDGKMKI 257
+ + KD ++I
Sbjct: 471 VASGGKDKCLRI 482
Score = 73.7 bits (173), Expect = 3e-12
Identities = 57/200 (28%), Positives = 90/200 (45%), Gaps = 11/200 (5%)
Query: 91 VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWV 150
V VT T + HS+ V SV FS G + + S D V+ W + GH +WV
Sbjct: 100 VRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWV 159
Query: 151 RCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG---LHLAWHP----SGC- 202
S DG +AS + LW+ +G+ + + L GH L+W P C
Sbjct: 160 LSISWSPDGKKLASGCKNGQILLWDPSTGKQVG--RTLAGHSKWITGLSWEPLHANPECR 217
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
YVA ++ G+V+++D + + H ++VT + G + +AS+D +K+ +
Sbjct: 218 YVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHD 276
Query: 263 GHPIFTLSGHNGPVNAVNFS 282
G TL GH VN + S
Sbjct: 277 GVLCRTLQGHGHWVNTMALS 296
Score = 67.7 bits (158), Expect = 2e-10
Identities = 46/169 (27%), Positives = 81/169 (47%), Gaps = 7/169 (4%)
Query: 141 SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPS 200
SS GH+ V S G +AS S D + + W+L + T K + L ++W P
Sbjct: 108 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 167
Query: 201 GCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQVA---IH--PSGSYILTASKDGK 254
G +A +G + L+D T V + + H++ +T ++ +H P Y+ ++SKDG
Sbjct: 168 GKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGS 227
Query: 255 MKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
++I D G L+GH V + + G + SA D+ + +W+ +
Sbjct: 228 VRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAH 275
>BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein.
Length = 484
Score = 98.7 bits (235), Expect = 9e-20
Identities = 71/294 (24%), Positives = 129/294 (43%), Gaps = 14/294 (4%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L+GH A+ ++ ++P + +A+ S D +V WDL + +GH V+ +++S GK
Sbjct: 109 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 168
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKA-HSQTVRSVQF-----SSDGSKIITASDDKVVK 130
+AS ++ + +W P+ G A HS+ + + + + + + ++S D V+
Sbjct: 169 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 228
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
+W T + GHT V C R DG ++ S S D++ K+W G T L+G
Sbjct: 229 IWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRT---LQG 284
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQV-AIHPSGSYILT 248
HG + A+ T + +L + A+++ + G L
Sbjct: 285 HGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLV 344
Query: 249 ASKDGKMKIL--DLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D L + P+ ++GH +N V FSP +SA DK + +W
Sbjct: 345 SGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLW 398
Score = 89.4 bits (212), Expect = 5e-17
Identities = 62/300 (20%), Positives = 127/300 (42%), Gaps = 8/300 (2%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWD-LRGTMRSYRFQGHDEAVMDVTF----- 71
KGH++ + ++ ++P+ +++A+ + +LLWD G GH + + +++
Sbjct: 152 KGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHA 211
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+ +Y+AS+S+D +VRIW T + H+Q+V +++ DG + +AS D+ +K+
Sbjct: 212 NPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKV 270
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W H + GH +WV +S D ++ + + D + K+
Sbjct: 271 WRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALS 330
Query: 192 GLHLAWHPSGCYVAVATSHGNVKLYD-IRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
+L + + + L+ + + H + QV P + +AS
Sbjct: 331 RYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASAS 390
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSE 310
D +K+ D G + +L GH V + +S S D + +W L+ +
Sbjct: 391 FDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMD 450
Score = 83.4 bits (197), Expect = 3e-15
Identities = 75/296 (25%), Positives = 123/296 (41%), Gaps = 13/296 (4%)
Query: 15 KQLKGHKNAITALYY-----NPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
+ L GH IT L + NP + +A+SS D SV +WD GH ++V +
Sbjct: 192 RTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCL 251
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVV 129
+ G + SAS+D+T+++W + H V ++ S+D + A +
Sbjct: 252 RWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEA 310
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDG-SIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+ + R + G + S SDD + LW+ E +
Sbjct: 311 SVNPQDLQGSLQELKERA-LSRYNLVRGQGPERLVSGSDDFTLFLWS--PAEDKKPLTRM 367
Query: 189 KGHGL---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSY 245
GH + + P VA A+ ++KL+D RT + H AV Q+A
Sbjct: 368 TGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRL 427
Query: 246 ILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
+++ S D +K+ D+ L GH V AV++SP G +S G DK + IW+
Sbjct: 428 LVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 483
Score = 80.2 bits (189), Expect = 3e-14
Identities = 57/252 (22%), Positives = 106/252 (42%), Gaps = 3/252 (1%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAV 66
TT C ++ L GH ++T L + D + ++S D ++ +W + QGH V
Sbjct: 232 TTAGRC-ERILTGHTQSVTCLRWG-GDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWV 289
Query: 67 MDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
+ S+ A + + GS K + + ++ ++++ SDD
Sbjct: 290 NTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDD 349
Query: 127 KVVKLWSTHKHKF-ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
+ LWS + K ++ GH + S D I+AS S DKS KLW+ +G+ + +
Sbjct: 350 FTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASL 409
Query: 186 KDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSY 245
+ +AW + +S +K++D++ L H + V V P G
Sbjct: 410 RGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQR 469
Query: 246 ILTASKDGKMKI 257
+ + KD ++I
Sbjct: 470 VASGGKDKCLRI 481
Score = 73.7 bits (173), Expect = 3e-12
Identities = 57/200 (28%), Positives = 90/200 (45%), Gaps = 11/200 (5%)
Query: 91 VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWV 150
V VT T + HS+ V SV FS G + + S D V+ W + GH +WV
Sbjct: 99 VRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWV 158
Query: 151 RCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG---LHLAWHP----SGC- 202
S DG +AS + LW+ +G+ + + L GH L+W P C
Sbjct: 159 LSISWSPDGKKLASGCKNGQILLWDPSTGKQVG--RTLAGHSKWITGLSWEPLHANPECR 216
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
YVA ++ G+V+++D + + H ++VT + G + +AS+D +K+ +
Sbjct: 217 YVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHD 275
Query: 263 GHPIFTLSGHNGPVNAVNFS 282
G TL GH VN + S
Sbjct: 276 GVLCRTLQGHGHWVNTMALS 295
Score = 67.7 bits (158), Expect = 2e-10
Identities = 46/169 (27%), Positives = 81/169 (47%), Gaps = 7/169 (4%)
Query: 141 SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPS 200
SS GH+ V S G +AS S D + + W+L + T K + L ++W P
Sbjct: 107 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 166
Query: 201 GCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQVA---IH--PSGSYILTASKDGK 254
G +A +G + L+D T V + + H++ +T ++ +H P Y+ ++SKDG
Sbjct: 167 GKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGS 226
Query: 255 MKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
++I D G L+GH V + + G + SA D+ + +W+ +
Sbjct: 227 VRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAH 274
>AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens
cDNA FLJ10458 fis, clone NT2RP1001457, highly similar to
Homo sapiens partial mRNA for beta-transducin family
protein. ).
Length = 485
Score = 98.7 bits (235), Expect = 9e-20
Identities = 71/294 (24%), Positives = 129/294 (43%), Gaps = 14/294 (4%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L+GH A+ ++ ++P + +A+ S D +V WDL + +GH V+ +++S GK
Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 169
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKA-HSQTVRSVQF-----SSDGSKIITASDDKVVK 130
+AS ++ + +W P+ G A HS+ + + + + + + ++S D V+
Sbjct: 170 KLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVR 229
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
+W T + GHT V C R DG ++ S S D++ K+W G T L+G
Sbjct: 230 IWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRT---LQG 285
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQV-AIHPSGSYILT 248
HG + A+ T + +L + A+++ + G L
Sbjct: 286 HGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLV 345
Query: 249 ASKDGKMKIL--DLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D L + P+ ++GH +N V FSP +SA DK + +W
Sbjct: 346 SGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLW 399
Score = 89.4 bits (212), Expect = 5e-17
Identities = 62/300 (20%), Positives = 127/300 (42%), Gaps = 8/300 (2%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWD-LRGTMRSYRFQGHDEAVMDVTF----- 71
KGH++ + ++ ++P+ +++A+ + +LLWD G GH + + +++
Sbjct: 153 KGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHA 212
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
+ +Y+AS+S+D +VRIW T + H+Q+V +++ DG + +AS D+ +K+
Sbjct: 213 NPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKV 271
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W H + GH +WV +S D ++ + + D + K+
Sbjct: 272 WRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALS 331
Query: 192 GLHLAWHPSGCYVAVATSHGNVKLYD-IRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
+L + + + L+ + + H + QV P + +AS
Sbjct: 332 RYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASAS 391
Query: 251 KDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSE 310
D +K+ D G + +L GH V + +S S D + +W L+ +
Sbjct: 392 FDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMD 451
Score = 83.4 bits (197), Expect = 3e-15
Identities = 75/296 (25%), Positives = 123/296 (41%), Gaps = 13/296 (4%)
Query: 15 KQLKGHKNAITALYY-----NPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
+ L GH IT L + NP + +A+SS D SV +WD GH ++V +
Sbjct: 193 RTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCL 252
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVV 129
+ G + SAS+D+T+++W + H V ++ S+D + A +
Sbjct: 253 RWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEA 311
Query: 130 KLWSTHKHKFISSFVGHTNWVRCARMSNDG-SIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+ + R + G + S SDD + LW+ E +
Sbjct: 312 SVNPQDLQGSLQELKERA-LSRYNLVRGQGPERLVSGSDDFTLFLWS--PAEDKKPLTRM 368
Query: 189 KGHGL---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSY 245
GH + + P VA A+ ++KL+D RT + H AV Q+A
Sbjct: 369 TGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRL 428
Query: 246 ILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWK 301
+++ S D +K+ D+ L GH V AV++SP G +S G DK + IW+
Sbjct: 429 LVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWR 484
Score = 80.2 bits (189), Expect = 3e-14
Identities = 57/252 (22%), Positives = 106/252 (42%), Gaps = 3/252 (1%)
Query: 7 TTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAV 66
TT C ++ L GH ++T L + D + ++S D ++ +W + QGH V
Sbjct: 233 TTAGRC-ERILTGHTQSVTCLRWG-GDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWV 290
Query: 67 MDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
+ S+ A + + GS K + + ++ ++++ SDD
Sbjct: 291 NTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDD 350
Query: 127 KVVKLWSTHKHKF-ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
+ LWS + K ++ GH + S D I+AS S DKS KLW+ +G+ + +
Sbjct: 351 FTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASL 410
Query: 186 KDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSY 245
+ +AW + +S +K++D++ L H + V V P G
Sbjct: 411 RGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQR 470
Query: 246 ILTASKDGKMKI 257
+ + KD ++I
Sbjct: 471 VASGGKDKCLRI 482
Score = 73.7 bits (173), Expect = 3e-12
Identities = 57/200 (28%), Positives = 90/200 (45%), Gaps = 11/200 (5%)
Query: 91 VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWV 150
V VT T + HS+ V SV FS G + + S D V+ W + GH +WV
Sbjct: 100 VRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWV 159
Query: 151 RCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG---LHLAWHP----SGC- 202
S DG +AS + LW+ +G+ + + L GH L+W P C
Sbjct: 160 LSISWSPDGKKLASGCKNGQILLWDPSTGKQVG--RTLAGHSKWITGLSWEPLHANPECR 217
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
YVA ++ G+V+++D + + H ++VT + G + +AS+D +K+ +
Sbjct: 218 YVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHD 276
Query: 263 GHPIFTLSGHNGPVNAVNFS 282
G TL GH VN + S
Sbjct: 277 GVLCRTLQGHGHWVNTMALS 296
Score = 67.7 bits (158), Expect = 2e-10
Identities = 46/169 (27%), Positives = 81/169 (47%), Gaps = 7/169 (4%)
Query: 141 SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPS 200
SS GH+ V S G +AS S D + + W+L + T K + L ++W P
Sbjct: 108 SSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 167
Query: 201 GCYVAVATSHGNVKLYDIRTHNLV-QYYSIHNEAVTQVA---IH--PSGSYILTASKDGK 254
G +A +G + L+D T V + + H++ +T ++ +H P Y+ ++SKDG
Sbjct: 168 GKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGS 227
Query: 255 MKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
++I D G L+GH V + + G + SA D+ + +W+ +
Sbjct: 228 VRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVWRAH 275
>AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 98.7 bits (235), Expect = 9e-20
Identities = 67/256 (26%), Positives = 120/256 (46%), Gaps = 16/256 (6%)
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H +AV FS G+ +AS DKT++++ KAH V FS+D I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDSG 179
T S DK VK+W++ + + ++ H+ V C +N ++A+ S D KLW+L+
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI------RTHNLVQYYSIHNEA 233
EC +T H + P +A ++ G +KL+D ++ N+ Q++ +
Sbjct: 734 ECRNTMFGRTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 793
Query: 234 VTQVAI-------HPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD 286
+ + G+ I+ A+K+ K+ + + + GH V+ V FSP G
Sbjct: 794 QEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGS 852
Query: 287 TFSSAGDDKLVFIWKT 302
+F ++ DD+ + +W+T
Sbjct: 853 SFLTSSDDQTIRLWET 868
Score = 85.4 bits (202), Expect = 9e-16
Identities = 61/256 (23%), Positives = 118/256 (46%), Gaps = 16/256 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 670
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ G TN V R S D ++ASCS D + KLW+ S + I+
Sbjct: 731 NQKECRNTMFGRTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 790
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+D++ +W G + VA + + L++ + + V H V V P
Sbjct: 791 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 242 SGSYILTASKDGKMKI 257
GS LT+S D +++
Sbjct: 850 DGSSFLTSSDDQTIRL 865
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/278 (24%), Positives = 116/278 (41%), Gaps = 19/278 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+AT S D + LWDL G +V FS K +AS S D T+++W T
Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGRTNSVNHCRFSPDDKLLASCSADGTLKLWDATSA 775
Query: 96 GSTGMFKAHS-------------QTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
V+ +S+DG++I+ A+ +K+ LW+T ++
Sbjct: 776 NERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVAD 834
Query: 143 FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGC 202
GH +WV S DGS + SDD++ +LW C ++ LK + + + +
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNSAVMLK-QEVDVVFQENEV 892
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
V ++L + RT + Y + V+ + P YI ++G ++IL+L+
Sbjct: 893 MVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 263 GHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ H V + F+ T S+ DD + +W
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 987
Score = 72.5 bits (170), Expect = 6e-12
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 2/160 (1%)
Query: 102 KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
+ H+ V FS DG +I + DK ++++ + + H + V C S D
Sbjct: 612 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN--VKLYDIR 219
IA+CS DK K+WN +GE +HTY + + S ++ +AT + +KL+D+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
+V P + + S DG +K+ D
Sbjct: 732 QKECRNTMFGRTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 927 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 986 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1161
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1162 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1203
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 893
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 894 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1005
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1006 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1065
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1066 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 58.0 bits (134), Expect = 1e-07
Identities = 55/233 (23%), Positives = 102/233 (43%), Gaps = 24/233 (10%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
K T E L ++K H++ + ++ +D+ IAT S+D V +W+ + + H E
Sbjct: 643 KAETGEKLL--EIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSE 700
Query: 65 AVMDVTFSSSGKY--MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
V F++S + +A+ S D +++W + +V +FS D + +
Sbjct: 701 QVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGRTNSVNHCRFSPDDKLLAS 760
Query: 123 ASDDKVVKLW---STHKHKFISSFVGHTNW----------VRCARMSNDGSIIASCSDDK 169
S D +KLW S ++ K I+ N V+C S DG+ I + +K
Sbjct: 761 CSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK 820
Query: 170 STKLWNLDSGECIHTYKDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIR 219
LWN DS + D +GH +H + + P G ++ ++L++ +
Sbjct: 821 -IFLWNTDSRSKV---ADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETK 869
>U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p
protein.
Length = 520
Score = 98.3 bits (234), Expect = 1e-19
Identities = 68/291 (23%), Positives = 122/291 (41%), Gaps = 9/291 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHD------EAVMDVTFS 72
G I+ +++PN + +AT+ LW + + +GH+ ++ T S
Sbjct: 227 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTKKEQLHSIPKSTVS 286
Query: 73 SSGK--YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVK 130
K +AS + D +V++W + H+ V V + G + T D+ +
Sbjct: 287 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 346
Query: 131 LWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
LW + I GH+ V DGS+ + D ++W+L +G CI +
Sbjct: 347 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 406
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP-SGSYILTA 249
+ + P+G ++A + K++D+R V H VT V P G+++LT
Sbjct: 407 EIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTG 466
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ D KI P+ TL+GH G V ++ S G ++ D+ +W
Sbjct: 467 AYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 517
Score = 78.2 bits (184), Expect = 1e-13
Identities = 58/245 (23%), Positives = 100/245 (40%), Gaps = 3/245 (1%)
Query: 14 KKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSS 73
K+QL + +L +P D +A+ + D SV LW L +GH V V +
Sbjct: 274 KEQLHSIPKSTVSL--DPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP 331
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
SG+++ + D++ R+W + HS V + F DGS T D ++W
Sbjct: 332 SGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWD 391
Query: 134 THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGL 193
+ I GH + S +G IA+ S D + K+W+L C++T +
Sbjct: 392 LRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVT 451
Query: 194 HLAWHP-SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
+ + P G ++ K++ + ++ + H V + I G I T S D
Sbjct: 452 GVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYD 511
Query: 253 GKMKI 257
K+
Sbjct: 512 RTFKL 516
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/202 (23%), Positives = 84/202 (41%), Gaps = 3/202 (1%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++GH + + ++P+ + + T+ D S LWDL +GH V D+ F G
Sbjct: 317 IEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS 376
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF-KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+ D R+W TG MF + H + + + FS +G I T S D K+W
Sbjct: 377 LAGTGGLDAFGRVW-DLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLR 435
Query: 136 KHKFISSFVGHTNWVRCARMSN-DGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
+ + + + H N V + G+ + + + D + K+W + T +G +
Sbjct: 436 QRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMG 495
Query: 195 LAWHPSGCYVAVATSHGNVKLY 216
L G +A + KL+
Sbjct: 496 LDISSDGQLIATCSYDRTFKLW 517
Score = 47.6 bits (108), Expect = 2e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 17 LKGHKNAITALYYNP-NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSG 75
+ H+N +T + + P + + T + DN+ +W G GH+ VM + SS G
Sbjct: 443 IPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDG 502
Query: 76 KYMASASRDKTVRIWV 91
+ +A+ S D+T ++W+
Sbjct: 503 QLIATCSYDRTFKLWM 518
>BT020045-1|AAV38848.1| 350|Homo sapiens unr-interacting protein
protein.
Length = 350
Score = 98.3 bits (234), Expect = 1e-19
Identities = 58/245 (23%), Positives = 121/245 (49%), Gaps = 6/245 (2%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
F GH AV T + A+A+ D T ++W V+G M AH V++V F+ D +
Sbjct: 55 FLGHKGAVWGATLNKDATKAATAAADFTAKVW-DAVSGDELMTLAHKHIVKTVDFTQDSN 113
Query: 119 KIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
++T DK+++++ +K + + GHT+ ++ A ++ I S +DDK+ +LW+
Sbjct: 114 YLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHA 172
Query: 178 SGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
+ + + + + + P G + V T ++ + + + ++ + +
Sbjct: 173 TMTEVKSL-NFNMSVSSMEYIPEG-EILVITYGRSIAFHSAVSLDPIKSFEA-PATINSA 229
Query: 238 AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLV 297
++HP +++ +D K+ D G + + GH GP++ V FSP G+ ++S +D +
Sbjct: 230 SLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTL 289
Query: 298 FIWKT 302
+W+T
Sbjct: 290 RLWQT 294
Score = 56.0 bits (129), Expect = 6e-07
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K++ GH + I + D+QI ++ D +V LWD TM + + +V + +
Sbjct: 137 KEISGHTSGIKKALWCSEDKQILSAD-DKTVRLWD-HATMTEVKSLNFNMSVSSMEYIPE 194
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
G+ + + +++ F+A + T+ S + ++ +D + +
Sbjct: 195 GEILV-ITYGRSIAFHSAVSLDPIKSFEAPA-TINSASLHPEKEFLVAGGEDFKLYKYDY 252
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
+ + + S+ GH + C R S DG + AS S+D + +LW G+ +K
Sbjct: 253 NSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWK 304
Score = 53.2 bits (122), Expect = 4e-06
Identities = 49/246 (19%), Positives = 97/246 (39%), Gaps = 6/246 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GHK A+ N + + AT++ D + +WD H V V F+ Y+
Sbjct: 57 GHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYL 115
Query: 79 ASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +DK +RI+ + H+ ++ + S+ +I++A DDK V+LW
Sbjct: 116 LTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSA-DDKTVRLWDHATM 174
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAW 197
+ S + V +G I+ + +S + S + I ++ + +
Sbjct: 175 TEVKS-LNFNMSVSSMEYIPEGEILV-ITYGRSIAFHSAVSLDPIKSF-EAPATINSASL 231
Query: 198 HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKI 257
HP ++ + YD + ++ Y H + V P G + S+DG +++
Sbjct: 232 HPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRL 291
Query: 258 LDLLEG 263
+ G
Sbjct: 292 WQTVVG 297
Score = 50.4 bits (115), Expect = 3e-05
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 11/248 (4%)
Query: 61 GHDEAVMDVTFSSS---GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDG 117
GH V+D+ FS G ++ SA +D + G F H V + D
Sbjct: 12 GHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 118 SKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
+K TA+ D K+W + + + H + V+ + D + + + DK ++++L+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMT-LAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 178 SGECIHTYKDLKGH--GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
E K++ GH G+ A S ++ V+L+D T V+ + N +V+
Sbjct: 131 KPEA--EPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNF-NMSVS 187
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ P G IL + + + PI + +N+ + P + + G+D
Sbjct: 188 SMEYIPEGE-ILVITYGRSIAFHSAVSLDPIKSFEA-PATINSASLHPEKEFLVAGGEDF 245
Query: 296 LVFIWKTN 303
++ + N
Sbjct: 246 KLYKYDYN 253
>BT020044-1|AAV38847.1| 350|Homo sapiens unr-interacting protein
protein.
Length = 350
Score = 98.3 bits (234), Expect = 1e-19
Identities = 58/245 (23%), Positives = 121/245 (49%), Gaps = 6/245 (2%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
F GH AV T + A+A+ D T ++W V+G M AH V++V F+ D +
Sbjct: 55 FLGHKGAVWGATLNKDATKAATAAADFTAKVW-DAVSGDELMTLAHKHIVKTVDFTQDSN 113
Query: 119 KIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
++T DK+++++ +K + + GHT+ ++ A ++ I S +DDK+ +LW+
Sbjct: 114 YLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHA 172
Query: 178 SGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
+ + + + + + P G + V T ++ + + + ++ + +
Sbjct: 173 TMTEVKSL-NFNMSVSSMEYIPEG-EILVITYGRSIAFHSAVSLDPIKSFEA-PATINSA 229
Query: 238 AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLV 297
++HP +++ +D K+ D G + + GH GP++ V FSP G+ ++S +D +
Sbjct: 230 SLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTL 289
Query: 298 FIWKT 302
+W+T
Sbjct: 290 RLWQT 294
Score = 56.0 bits (129), Expect = 6e-07
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K++ GH + I + D+QI ++ D +V LWD TM + + +V + +
Sbjct: 137 KEISGHTSGIKKALWCSEDKQILSAD-DKTVRLWD-HATMTEVKSLNFNMSVSSMEYIPE 194
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
G+ + + +++ F+A + T+ S + ++ +D + +
Sbjct: 195 GEILV-ITYGRSIAFHSAVSLDPIKSFEAPA-TINSASLHPEKEFLVAGGEDFKLYKYDY 252
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
+ + + S+ GH + C R S DG + AS S+D + +LW G+ +K
Sbjct: 253 NSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWK 304
Score = 53.2 bits (122), Expect = 4e-06
Identities = 49/246 (19%), Positives = 97/246 (39%), Gaps = 6/246 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GHK A+ N + + AT++ D + +WD H V V F+ Y+
Sbjct: 57 GHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYL 115
Query: 79 ASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +DK +RI+ + H+ ++ + S+ +I++A DDK V+LW
Sbjct: 116 LTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSA-DDKTVRLWDHATM 174
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAW 197
+ S + V +G I+ + +S + S + I ++ + +
Sbjct: 175 TEVKS-LNFNMSVSSMEYIPEGEILV-ITYGRSIAFHSAVSLDPIKSF-EAPATINSASL 231
Query: 198 HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKI 257
HP ++ + YD + ++ Y H + V P G + S+DG +++
Sbjct: 232 HPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRL 291
Query: 258 LDLLEG 263
+ G
Sbjct: 292 WQTVVG 297
Score = 50.4 bits (115), Expect = 3e-05
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 11/248 (4%)
Query: 61 GHDEAVMDVTFSSS---GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDG 117
GH V+D+ FS G ++ SA +D + G F H V + D
Sbjct: 12 GHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 118 SKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
+K TA+ D K+W + + + H + V+ + D + + + DK ++++L+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMT-LAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 178 SGECIHTYKDLKGH--GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
E K++ GH G+ A S ++ V+L+D T V+ + N +V+
Sbjct: 131 KPEA--EPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNF-NMSVS 187
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ P G IL + + + PI + +N+ + P + + G+D
Sbjct: 188 SMEYIPEGE-ILVITYGRSIAFHSAVSLDPIKSFEA-PATINSASLHPEKEFLVAGGEDF 245
Query: 296 LVFIWKTN 303
++ + N
Sbjct: 246 KLYKYDYN 253
>BC062306-1|AAH62306.1| 350|Homo sapiens serine/threonine kinase
receptor associated protein protein.
Length = 350
Score = 98.3 bits (234), Expect = 1e-19
Identities = 58/245 (23%), Positives = 121/245 (49%), Gaps = 6/245 (2%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
F GH AV T + A+A+ D T ++W V+G M AH V++V F+ D +
Sbjct: 55 FLGHKGAVWGATLNKDATKAATAAADFTAKVW-DAVSGDELMTLAHKHIVKTVDFTQDSN 113
Query: 119 KIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
++T DK+++++ +K + + GHT+ ++ A ++ I S +DDK+ +LW+
Sbjct: 114 YLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHA 172
Query: 178 SGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
+ + + + + + P G + V T ++ + + + ++ + +
Sbjct: 173 TMTEVKSL-NFNMSVSSMEYIPEG-EILVITYGRSIAFHSAVSLDPIKSFEA-PATINSA 229
Query: 238 AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLV 297
++HP +++ +D K+ D G + + GH GP++ V FSP G+ ++S +D +
Sbjct: 230 SLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTL 289
Query: 298 FIWKT 302
+W+T
Sbjct: 290 RLWQT 294
Score = 56.0 bits (129), Expect = 6e-07
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K++ GH + I + D+QI ++ D +V LWD TM + + +V + +
Sbjct: 137 KEISGHTSGIKKALWCSEDKQILSAD-DKTVRLWD-HATMTEVKSLNFNMSVSSMEYIPE 194
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
G+ + + +++ F+A + T+ S + ++ +D + +
Sbjct: 195 GEILV-ITYGRSIAFHSAVSLDPIKSFEAPA-TINSASLHPEKEFLVAGGEDFKLYKYDY 252
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
+ + + S+ GH + C R S DG + AS S+D + +LW G+ +K
Sbjct: 253 NSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWK 304
Score = 53.2 bits (122), Expect = 4e-06
Identities = 49/246 (19%), Positives = 97/246 (39%), Gaps = 6/246 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GHK A+ N + + AT++ D + +WD H V V F+ Y+
Sbjct: 57 GHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYL 115
Query: 79 ASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +DK +RI+ + H+ ++ + S+ +I++A DDK V+LW
Sbjct: 116 LTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSA-DDKTVRLWDHATM 174
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAW 197
+ S + V +G I+ + +S + S + I ++ + +
Sbjct: 175 TEVKS-LNFNMSVSSMEYIPEGEILV-ITYGRSIAFHSAVSLDPIKSF-EAPATINSASL 231
Query: 198 HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKI 257
HP ++ + YD + ++ Y H + V P G + S+DG +++
Sbjct: 232 HPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRL 291
Query: 258 LDLLEG 263
+ G
Sbjct: 292 WQTVVG 297
Score = 50.4 bits (115), Expect = 3e-05
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 11/248 (4%)
Query: 61 GHDEAVMDVTFSSS---GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDG 117
GH V+D+ FS G ++ SA +D + G F H V + D
Sbjct: 12 GHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 118 SKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
+K TA+ D K+W + + + H + V+ + D + + + DK ++++L+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMT-LAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 178 SGECIHTYKDLKGH--GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
E K++ GH G+ A S ++ V+L+D T V+ + N +V+
Sbjct: 131 KPEA--EPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNF-NMSVS 187
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ P G IL + + + PI + +N+ + P + + G+D
Sbjct: 188 SMEYIPEGE-ILVITYGRSIAFHSAVSLDPIKSFEA-PATINSASLHPEKEFLVAGGEDF 245
Query: 296 LVFIWKTN 303
++ + N
Sbjct: 246 KLYKYDYN 253
>BC000162-1|AAH00162.1| 350|Homo sapiens serine/threonine kinase
receptor associated protein protein.
Length = 350
Score = 98.3 bits (234), Expect = 1e-19
Identities = 58/245 (23%), Positives = 121/245 (49%), Gaps = 6/245 (2%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
F GH AV T + A+A+ D T ++W V+G M AH V++V F+ D +
Sbjct: 55 FLGHKGAVWGATLNKDATKAATAAADFTAKVW-DAVSGDELMTLAHKHIVKTVDFTQDSN 113
Query: 119 KIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
++T DK+++++ +K + + GHT+ ++ A ++ I S +DDK+ +LW+
Sbjct: 114 YLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHA 172
Query: 178 SGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
+ + + + + + P G + V T ++ + + + ++ + +
Sbjct: 173 TMTEVKSL-NFNMSVSSMEYIPEG-EILVITYGRSIAFHSAVSLDPIKSFEA-PATINSA 229
Query: 238 AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLV 297
++HP +++ +D K+ D G + + GH GP++ V FSP G+ ++S +D +
Sbjct: 230 SLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTL 289
Query: 298 FIWKT 302
+W+T
Sbjct: 290 RLWQT 294
Score = 56.0 bits (129), Expect = 6e-07
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K++ GH + I + D+QI ++ D +V LWD TM + + +V + +
Sbjct: 137 KEISGHTSGIKKALWCSEDKQILSAD-DKTVRLWD-HATMTEVKSLNFNMSVSSMEYIPE 194
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
G+ + + +++ F+A + T+ S + ++ +D + +
Sbjct: 195 GEILV-ITYGRSIAFHSAVSLDPIKSFEAPA-TINSASLHPEKEFLVAGGEDFKLYKYDY 252
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
+ + + S+ GH + C R S DG + AS S+D + +LW G+ +K
Sbjct: 253 NSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWK 304
Score = 53.2 bits (122), Expect = 4e-06
Identities = 49/246 (19%), Positives = 97/246 (39%), Gaps = 6/246 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GHK A+ N + + AT++ D + +WD H V V F+ Y+
Sbjct: 57 GHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYL 115
Query: 79 ASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +DK +RI+ + H+ ++ + S+ +I++A DDK V+LW
Sbjct: 116 LTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSA-DDKTVRLWDHATM 174
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAW 197
+ S + V +G I+ + +S + S + I ++ + +
Sbjct: 175 TEVKS-LNFNMSVSSMEYIPEGEILV-ITYGRSIAFHSAVSLDPIKSF-EAPATINSASL 231
Query: 198 HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKI 257
HP ++ + YD + ++ Y H + V P G + S+DG +++
Sbjct: 232 HPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRL 291
Query: 258 LDLLEG 263
+ G
Sbjct: 292 WQTVVG 297
Score = 50.4 bits (115), Expect = 3e-05
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 11/248 (4%)
Query: 61 GHDEAVMDVTFSSS---GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDG 117
GH V+D+ FS G ++ SA +D + G F H V + D
Sbjct: 12 GHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 118 SKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
+K TA+ D K+W + + + H + V+ + D + + + DK ++++L+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMT-LAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 178 SGECIHTYKDLKGH--GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
E K++ GH G+ A S ++ V+L+D T V+ + N +V+
Sbjct: 131 KPEA--EPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNF-NMSVS 187
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ P G IL + + + PI + +N+ + P + + G+D
Sbjct: 188 SMEYIPEGE-ILVITYGRSIAFHSAVSLDPIKSFEA-PATINSASLHPEKEFLVAGGEDF 245
Query: 296 LVFIWKTN 303
++ + N
Sbjct: 246 KLYKYDYN 253
>AY049776-1|AAL15433.1| 350|Homo sapiens unr-interacting protein
protein.
Length = 350
Score = 98.3 bits (234), Expect = 1e-19
Identities = 58/245 (23%), Positives = 121/245 (49%), Gaps = 6/245 (2%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
F GH AV T + A+A+ D T ++W V+G M AH V++V F+ D +
Sbjct: 55 FLGHKGAVWGATLNKDATKAATAAADFTAKVW-DAVSGDELMTLAHKHIVKTVDFTQDSN 113
Query: 119 KIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
++T DK+++++ +K + + GHT+ ++ A ++ I S +DDK+ +LW+
Sbjct: 114 YLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHA 172
Query: 178 SGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
+ + + + + + P G + V T ++ + + + ++ + +
Sbjct: 173 TMTEVKSL-NFNMSVSSMEYIPEG-EILVITYGRSIAFHSAVSLDPIKSFEA-PATINSA 229
Query: 238 AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLV 297
++HP +++ +D K+ D G + + GH GP++ V FSP G+ ++S +D +
Sbjct: 230 SLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTL 289
Query: 298 FIWKT 302
+W+T
Sbjct: 290 RLWQT 294
Score = 56.0 bits (129), Expect = 6e-07
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K++ GH + I + D+QI ++ D +V LWD TM + + +V + +
Sbjct: 137 KEISGHTSGIKKALWCSEDKQILSAD-DKTVRLWD-HATMTEVKSLNFNMSVSSMEYIPE 194
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
G+ + + +++ F+A + T+ S + ++ +D + +
Sbjct: 195 GEILV-ITYGRSIAFHSAVSLDPIKSFEAPA-TINSASLHPEKEFLVAGGEDFKLYKYDY 252
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
+ + + S+ GH + C R S DG + AS S+D + +LW G+ +K
Sbjct: 253 NSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWK 304
Score = 53.2 bits (122), Expect = 4e-06
Identities = 49/246 (19%), Positives = 97/246 (39%), Gaps = 6/246 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GHK A+ N + + AT++ D + +WD H V V F+ Y+
Sbjct: 57 GHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYL 115
Query: 79 ASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +DK +RI+ + H+ ++ + S+ +I++A DDK V+LW
Sbjct: 116 LTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSA-DDKTVRLWDHATM 174
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAW 197
+ S + V +G I+ + +S + S + I ++ + +
Sbjct: 175 TEVKS-LNFNMSVSSMEYIPEGEILV-ITYGRSIAFHSAVSLDPIKSF-EAPATINSASL 231
Query: 198 HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKI 257
HP ++ + YD + ++ Y H + V P G + S+DG +++
Sbjct: 232 HPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRL 291
Query: 258 LDLLEG 263
+ G
Sbjct: 292 WQTVVG 297
Score = 50.4 bits (115), Expect = 3e-05
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 11/248 (4%)
Query: 61 GHDEAVMDVTFSSS---GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDG 117
GH V+D+ FS G ++ SA +D + G F H V + D
Sbjct: 12 GHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 118 SKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
+K TA+ D K+W + + + H + V+ + D + + + DK ++++L+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMT-LAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 178 SGECIHTYKDLKGH--GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
E K++ GH G+ A S ++ V+L+D T V+ + N +V+
Sbjct: 131 KPEA--EPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNF-NMSVS 187
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ P G IL + + + PI + +N+ + P + + G+D
Sbjct: 188 SMEYIPEGE-ILVITYGRSIAFHSAVSLDPIKSFEA-PATINSASLHPEKEFLVAGGEDF 245
Query: 296 LVFIWKTN 303
++ + N
Sbjct: 246 KLYKYDYN 253
>AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 98.3 bits (234), Expect = 1e-19
Identities = 67/256 (26%), Positives = 120/256 (46%), Gaps = 16/256 (6%)
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H +AV FS G+ +AS DKT++++ KAH V FS+D I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDSG 179
T S DK VK+W++ + + ++ H+ V C +N ++A+ S D KLW+L+
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI------RTHNLVQYYSIHNEA 233
EC +T H + P +A ++ G +KL+D ++ N+ Q++ +
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 793
Query: 234 VTQVAI-------HPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD 286
+ + G+ I+ A+K+ K+ + + + GH V+ V FSP G
Sbjct: 794 QEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGS 852
Query: 287 TFSSAGDDKLVFIWKT 302
+F ++ DD+ + +W+T
Sbjct: 853 SFLTSSDDQTIRLWET 868
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/256 (24%), Positives = 119/256 (46%), Gaps = 16/256 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 670
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN V R S D ++ASCS D + KLW+ S + I+
Sbjct: 731 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 790
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+D++ +W G + VA + + L++ + + V H V V P
Sbjct: 791 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 242 SGSYILTASKDGKMKI 257
GS LT+S D +++
Sbjct: 850 DGSSFLTSSDDQTIRL 865
Score = 83.4 bits (197), Expect = 3e-15
Identities = 68/278 (24%), Positives = 117/278 (42%), Gaps = 19/278 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+AT S D + LWDL GH +V FS K +AS S D T+++W T
Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSA 775
Query: 96 GSTGMFKAHS-------------QTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
V+ +S+DG++I+ A+ +K+ LW+T ++
Sbjct: 776 NERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVAD 834
Query: 143 FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGC 202
GH +WV S DGS + SDD++ +LW C ++ LK + + + +
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNSAVMLK-QEVDVVFQENEV 892
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
V ++L + RT + Y + V+ + P YI ++G ++IL+L+
Sbjct: 893 MVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 263 GHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ H V + F+ T S+ DD + +W
Sbjct: 950 NRIFQSRFQHKKTVWRIQFTADEKTLISSSDDAEIQVW 987
Score = 75.8 bits (178), Expect = 7e-13
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 2/160 (1%)
Query: 102 KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
+ H+ V FS DG +I + DK ++++ + + H + V C S D
Sbjct: 612 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN--VKLYDIR 219
IA+CS DK K+WN +GE +HTY + + S ++ +AT + +KL+D+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
H +V P + + S DG +K+ D
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 69.3 bits (162), Expect = 6e-11
Identities = 58/282 (20%), Positives = 127/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 927 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWRIQFTADEKTLISSSDDAEIQ 985
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + ++++ S D VK+W+ FV H
Sbjct: 986 VWNWQLDKCI-FLRGHQETVKDFRLLKN-PRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1161
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1162 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1203
Score = 64.5 bits (150), Expect = 2e-09
Identities = 67/298 (22%), Positives = 123/298 (41%), Gaps = 23/298 (7%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 893
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 894 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH----- 191
++ S H V + + D + S SDD ++WN +CI L+GH
Sbjct: 950 NRIFQSRFQHKKTVWRIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1005
Query: 192 GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-A 249
L +P + + G VK+++I T N + + H V I H + + T A
Sbjct: 1006 DFRLLKNPR---LLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSA 1062
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1063 DKTAKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 61.3 bits (142), Expect = 2e-08
Identities = 56/233 (24%), Positives = 103/233 (44%), Gaps = 24/233 (10%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
K T E L ++K H++ + ++ +D+ IAT S+D V +W+ + + H E
Sbjct: 643 KAETGEKLL--EIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSE 700
Query: 65 AVMDVTFSSSGKY--MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
V F++S + +A+ S D +++W H+ +V +FS D + +
Sbjct: 701 QVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLAS 760
Query: 123 ASDDKVVKLW---STHKHKFISSFVGHTNW----------VRCARMSNDGSIIASCSDDK 169
S D +KLW S ++ K I+ N V+C S DG+ I + +K
Sbjct: 761 CSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK 820
Query: 170 STKLWNLDSGECIHTYKDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIR 219
LWN DS + D +GH +H + + P G ++ ++L++ +
Sbjct: 821 -IFLWNTDSRSKV---ADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETK 869
>AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 98.3 bits (234), Expect = 1e-19
Identities = 67/256 (26%), Positives = 120/256 (46%), Gaps = 16/256 (6%)
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H +AV FS G+ +AS DKT++++ KAH V FS+D I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDSG 179
T S DK VK+W++ + + ++ H+ V C +N ++A+ S D KLW+L+
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI------RTHNLVQYYSIHNEA 233
EC +T H + P +A ++ G +KL+D ++ N+ Q++ +
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 793
Query: 234 VTQVAI-------HPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD 286
+ + G+ I+ A+K+ K+ + + + GH V+ V FSP G
Sbjct: 794 QEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGS 852
Query: 287 TFSSAGDDKLVFIWKT 302
+F ++ DD+ + +W+T
Sbjct: 853 SFLTSSDDQTIRLWET 868
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/256 (24%), Positives = 119/256 (46%), Gaps = 16/256 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 670
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN V R S D ++ASCS D + KLW+ S + I+
Sbjct: 731 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 790
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+D++ +W G + VA + + L++ + + V H V V P
Sbjct: 791 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 242 SGSYILTASKDGKMKI 257
GS LT+S D +++
Sbjct: 850 DGSSFLTSSDDQTIRL 865
Score = 83.0 bits (196), Expect = 5e-15
Identities = 68/278 (24%), Positives = 117/278 (42%), Gaps = 19/278 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+AT S D + LWDL GH +V FS K +AS S D T+++W T
Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSA 775
Query: 96 GSTGMFKAHS-------------QTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
V+ +S+DG++I+ A+ +K+ LW+T ++
Sbjct: 776 NERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVAD 834
Query: 143 FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGC 202
GH +WV S DGS + SDD++ +LW C ++ LK + + + +
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNSAVMLK-QEVDVVFQENEV 892
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
V ++L + RT + Y + V+ + P YI ++G ++IL+L+
Sbjct: 893 MVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 263 GHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ H V + F+ T S+ DD + +W
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 987
Score = 75.8 bits (178), Expect = 7e-13
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 2/160 (1%)
Query: 102 KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
+ H+ V FS DG +I + DK ++++ + + H + V C S D
Sbjct: 612 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN--VKLYDIR 219
IA+CS DK K+WN +GE +HTY + + S ++ +AT + +KL+D+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
H +V P + + S DG +K+ D
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 927 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 986 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1161
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1162 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1203
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 893
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 894 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1005
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1006 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1065
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1066 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 61.3 bits (142), Expect = 2e-08
Identities = 56/233 (24%), Positives = 103/233 (44%), Gaps = 24/233 (10%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
K T E L ++K H++ + ++ +D+ IAT S+D V +W+ + + H E
Sbjct: 643 KAETGEKLL--EIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSE 700
Query: 65 AVMDVTFSSSGKY--MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
V F++S + +A+ S D +++W H+ +V +FS D + +
Sbjct: 701 QVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLAS 760
Query: 123 ASDDKVVKLW---STHKHKFISSFVGHTNW----------VRCARMSNDGSIIASCSDDK 169
S D +KLW S ++ K I+ N V+C S DG+ I + +K
Sbjct: 761 CSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK 820
Query: 170 STKLWNLDSGECIHTYKDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIR 219
LWN DS + D +GH +H + + P G ++ ++L++ +
Sbjct: 821 -IFLWNTDSRSKV---ADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETK 869
>AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 98.3 bits (234), Expect = 1e-19
Identities = 67/256 (26%), Positives = 120/256 (46%), Gaps = 16/256 (6%)
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H +AV FS G+ +AS DKT++++ KAH V FS+D I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDSG 179
T S DK VK+W++ + + ++ H+ V C +N ++A+ S D KLW+L+
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI------RTHNLVQYYSIHNEA 233
EC +T H + P +A ++ G +KL+D ++ N+ Q++ +
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 793
Query: 234 VTQVAI-------HPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD 286
+ + G+ I+ A+K+ K+ + + + GH V+ V FSP G
Sbjct: 794 QEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGS 852
Query: 287 TFSSAGDDKLVFIWKT 302
+F ++ DD+ + +W+T
Sbjct: 853 SFLTSSDDQTIRLWET 868
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/256 (24%), Positives = 119/256 (46%), Gaps = 16/256 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 670
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDCFLKLWDL 730
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN V R S D ++ASCS D + KLW+ S + I+
Sbjct: 731 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 790
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+D++ +W G + VA + + L++ + + V H V V P
Sbjct: 791 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 242 SGSYILTASKDGKMKI 257
GS LT+S D +++
Sbjct: 850 DGSSFLTSSDDQTIRL 865
Score = 83.0 bits (196), Expect = 5e-15
Identities = 68/278 (24%), Positives = 117/278 (42%), Gaps = 19/278 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+AT S D + LWDL GH +V FS K +AS S D T+++W T
Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSA 775
Query: 96 GSTGMFKAHS-------------QTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
V+ +S+DG++I+ A+ +K+ LW+T ++
Sbjct: 776 NERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVAD 834
Query: 143 FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGC 202
GH +WV S DGS + SDD++ +LW C ++ LK + + + +
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNSAVMLK-QEVDVVFQENEV 892
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
V ++L + RT + Y + V+ + P YI ++G ++IL+L+
Sbjct: 893 MVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 263 GHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ H V + F+ T S+ DD + +W
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 987
Score = 77.0 bits (181), Expect = 3e-13
Identities = 43/160 (26%), Positives = 71/160 (44%), Gaps = 2/160 (1%)
Query: 102 KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
+ H+ V FS DG +I + DK ++++ + + H + V C S D
Sbjct: 612 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKD--LKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
IA+CS DK K+WN +GE +HTY + + + H A +A +S +KL+D+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDCFLKLWDLN 731
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
H +V P + + S DG +K+ D
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 927 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 986 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1161
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1162 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1203
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 893
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 894 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1005
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1006 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1065
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1066 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 61.3 bits (142), Expect = 2e-08
Identities = 56/233 (24%), Positives = 103/233 (44%), Gaps = 24/233 (10%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
K T E L ++K H++ + ++ +D+ IAT S+D V +W+ + + H E
Sbjct: 643 KAETGEKLL--EIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSE 700
Query: 65 AVMDVTFSSSGKY--MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
V F++S + +A+ S D +++W H+ +V +FS D + +
Sbjct: 701 QVNCCHFANSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLAS 760
Query: 123 ASDDKVVKLW---STHKHKFISSFVGHTNW----------VRCARMSNDGSIIASCSDDK 169
S D +KLW S ++ K I+ N V+C S DG+ I + +K
Sbjct: 761 CSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK 820
Query: 170 STKLWNLDSGECIHTYKDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIR 219
LWN DS + D +GH +H + + P G ++ ++L++ +
Sbjct: 821 -IFLWNTDSRSKV---ADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETK 869
>AJ010025-1|CAB38041.1| 350|Homo sapiens unr-interacting protein
protein.
Length = 350
Score = 98.3 bits (234), Expect = 1e-19
Identities = 58/245 (23%), Positives = 121/245 (49%), Gaps = 6/245 (2%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
F GH AV T + A+A+ D T ++W V+G M AH V++V F+ D +
Sbjct: 55 FLGHKGAVWGATLNKDATKAATAAADFTAKVW-DAVSGDELMTLAHKHIVKTVDFTQDSN 113
Query: 119 KIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
++T DK+++++ +K + + GHT+ ++ A ++ I S +DDK+ +LW+
Sbjct: 114 YLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHA 172
Query: 178 SGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
+ + + + + + P G + V T ++ + + + ++ + +
Sbjct: 173 TMTEVKSL-NFNMSVSSMEYIPEG-EILVITYGRSIAFHSAVSLDPIKSFEA-PATINSA 229
Query: 238 AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLV 297
++HP +++ +D K+ D G + + GH GP++ V FSP G+ ++S +D +
Sbjct: 230 SLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTL 289
Query: 298 FIWKT 302
+W+T
Sbjct: 290 RLWQT 294
Score = 56.0 bits (129), Expect = 6e-07
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K++ GH + I + D+QI ++ D +V LWD TM + + +V + +
Sbjct: 137 KEISGHTSGIKKALWCSEDKQILSAD-DKTVRLWD-HATMTEVKSLNFNMSVSSMEYIPE 194
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
G+ + + +++ F+A + T+ S + ++ +D + +
Sbjct: 195 GEILV-ITYGRSIAFHSAVSLDPIKSFEAPA-TINSASLHPEKEFLVAGGEDFKLYKYDY 252
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
+ + + S+ GH + C R S DG + AS S+D + +LW G+ +K
Sbjct: 253 NSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWK 304
Score = 53.2 bits (122), Expect = 4e-06
Identities = 49/246 (19%), Positives = 97/246 (39%), Gaps = 6/246 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GHK A+ N + + AT++ D + +WD H V V F+ Y+
Sbjct: 57 GHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYL 115
Query: 79 ASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +DK +RI+ + H+ ++ + S+ +I++A DDK V+LW
Sbjct: 116 LTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSA-DDKTVRLWDHATM 174
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAW 197
+ S + V +G I+ + +S + S + I ++ + +
Sbjct: 175 TEVKS-LNFNMSVSSMEYIPEGEILV-ITYGRSIAFHSAVSLDPIKSF-EAPATINSASL 231
Query: 198 HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKI 257
HP ++ + YD + ++ Y H + V P G + S+DG +++
Sbjct: 232 HPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRL 291
Query: 258 LDLLEG 263
+ G
Sbjct: 292 WQTVVG 297
Score = 50.4 bits (115), Expect = 3e-05
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 11/248 (4%)
Query: 61 GHDEAVMDVTFSSS---GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDG 117
GH V+D+ FS G ++ SA +D + G F H V + D
Sbjct: 12 GHTRPVVDLAFSGITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 118 SKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
+K TA+ D K+W + + + H + V+ + D + + + DK ++++L+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMT-LAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 178 SGECIHTYKDLKGH--GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
E K++ GH G+ A S ++ V+L+D T V+ + N +V+
Sbjct: 131 KPEA--EPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNF-NMSVS 187
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ P G IL + + + PI + +N+ + P + + G+D
Sbjct: 188 SMEYIPEGE-ILVITYGRSIAFHSAVSLDPIKSFEA-PATINSASLHPEKEFLVAGGEDF 245
Query: 296 LVFIWKTN 303
++ + N
Sbjct: 246 KLYKYDYN 253
>AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1194
Score = 98.3 bits (234), Expect = 1e-19
Identities = 67/256 (26%), Positives = 120/256 (46%), Gaps = 16/256 (6%)
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H +AV FS G+ +AS DKT++++ KAH V FS+D I
Sbjct: 603 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 662
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDSG 179
T S DK VK+W++ + + ++ H+ V C +N ++A+ S D KLW+L+
Sbjct: 663 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 722
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI------RTHNLVQYYSIHNEA 233
EC +T H + P +A ++ G +KL+D ++ N+ Q++ +
Sbjct: 723 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 782
Query: 234 VTQVAI-------HPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD 286
+ + G+ I+ A+K+ K+ + + + GH V+ V FSP G
Sbjct: 783 QEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGS 841
Query: 287 TFSSAGDDKLVFIWKT 302
+F ++ DD+ + +W+T
Sbjct: 842 SFLTSSDDQTIRLWET 857
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/256 (24%), Positives = 119/256 (46%), Gaps = 16/256 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 600 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 659
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 660 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 719
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN V R S D ++ASCS D + KLW+ S + I+
Sbjct: 720 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 779
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+D++ +W G + VA + + L++ + + V H V V P
Sbjct: 780 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSP 838
Query: 242 SGSYILTASKDGKMKI 257
GS LT+S D +++
Sbjct: 839 DGSSFLTSSDDQTIRL 854
Score = 83.0 bits (196), Expect = 5e-15
Identities = 68/278 (24%), Positives = 117/278 (42%), Gaps = 19/278 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+AT S D + LWDL GH +V FS K +AS S D T+++W T
Sbjct: 705 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSA 764
Query: 96 GSTGMFKAHS-------------QTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
V+ +S+DG++I+ A+ +K+ LW+T ++
Sbjct: 765 NERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVAD 823
Query: 143 FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGC 202
GH +WV S DGS + SDD++ +LW C ++ LK + + + +
Sbjct: 824 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNSAVMLK-QEVDVVFQENEV 881
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
V ++L + RT + Y + V+ + P YI ++G ++IL+L+
Sbjct: 882 MVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 938
Query: 263 GHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ H V + F+ T S+ DD + +W
Sbjct: 939 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 976
Score = 75.8 bits (178), Expect = 7e-13
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 2/160 (1%)
Query: 102 KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
+ H+ V FS DG +I + DK ++++ + + H + V C S D
Sbjct: 601 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 660
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN--VKLYDIR 219
IA+CS DK K+WN +GE +HTY + + S ++ +AT + +KL+D+
Sbjct: 661 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 720
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
H +V P + + S DG +K+ D
Sbjct: 721 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 760
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 916 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 974
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 975 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1032
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1033 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1092
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1093 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1150
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1151 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1192
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 825 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 882
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 883 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 938
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 939 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 994
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 995 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1054
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1055 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1107
Score = 61.3 bits (142), Expect = 2e-08
Identities = 56/233 (24%), Positives = 103/233 (44%), Gaps = 24/233 (10%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
K T E L ++K H++ + ++ +D+ IAT S+D V +W+ + + H E
Sbjct: 632 KAETGEKLL--EIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSE 689
Query: 65 AVMDVTFSSSGKY--MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
V F++S + +A+ S D +++W H+ +V +FS D + +
Sbjct: 690 QVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLAS 749
Query: 123 ASDDKVVKLW---STHKHKFISSFVGHTNW----------VRCARMSNDGSIIASCSDDK 169
S D +KLW S ++ K I+ N V+C S DG+ I + +K
Sbjct: 750 CSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK 809
Query: 170 STKLWNLDSGECIHTYKDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIR 219
LWN DS + D +GH +H + + P G ++ ++L++ +
Sbjct: 810 -IFLWNTDSRSKV---ADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETK 858
>AB024327-1|BAA75544.1| 350|Homo sapiens WD-40 repeat protein
protein.
Length = 350
Score = 98.3 bits (234), Expect = 1e-19
Identities = 58/245 (23%), Positives = 121/245 (49%), Gaps = 6/245 (2%)
Query: 59 FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGS 118
F GH AV T + A+A+ D T ++W V+G M AH V++V F+ D +
Sbjct: 55 FLGHKGAVWGATLNKDATKAATAAADFTAKVW-DAVSGDELMTLAHKHIVKTVDFTQDSN 113
Query: 119 KIITASDDKVVKLWSTHKHKFISSFV-GHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
++T DK+++++ +K + + GHT+ ++ A ++ I S +DDK+ +LW+
Sbjct: 114 YLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVRLWDHA 172
Query: 178 SGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQV 237
+ + + + + + P G + V T ++ + + + ++ + +
Sbjct: 173 TMTEVKSL-NFNMSVSSMEYIPEG-EILVITYGRSIAFHSAVSLDPIKSFEA-PATINSA 229
Query: 238 AIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLV 297
++HP +++ +D K+ D G + + GH GP++ V FSP G+ ++S +D +
Sbjct: 230 SLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTL 289
Query: 298 FIWKT 302
+W+T
Sbjct: 290 RLWQT 294
Score = 56.0 bits (129), Expect = 6e-07
Identities = 37/172 (21%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K++ GH + I + D+QI ++ D +V LWD TM + + +V + +
Sbjct: 137 KEISGHTSGIKKALWCSEDKQILSAD-DKTVRLWD-HATMTEVKSLNFNMSVSSMEYIPE 194
Query: 75 GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
G+ + + +++ F+A + T+ S + ++ +D + +
Sbjct: 195 GEILV-ITYGRSIAFHSAVSLDPIKSFEAPA-TINSASLHPEKEFLVAGGEDFKLYKYDY 252
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
+ + + S+ GH + C R S DG + AS S+D + +LW G+ +K
Sbjct: 253 NSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLWK 304
Score = 53.2 bits (122), Expect = 4e-06
Identities = 49/246 (19%), Positives = 97/246 (39%), Gaps = 6/246 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GHK A+ N + + AT++ D + +WD H V V F+ Y+
Sbjct: 57 GHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYL 115
Query: 79 ASASRDKTVRIW-VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH 137
+ +DK +RI+ + H+ ++ + S+ +I++A DDK V+LW
Sbjct: 116 LTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSA-DDKTVRLWDHATM 174
Query: 138 KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAW 197
+ S + V +G I+ + +S + S + I ++ + +
Sbjct: 175 TEVKS-LNFNMSVSSMEYIPEGEILV-ITYGRSIAFHSAVSLDPIKSF-EAPATINSASL 231
Query: 198 HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKI 257
HP ++ + YD + ++ Y H + V P G + S+DG +++
Sbjct: 232 HPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRL 291
Query: 258 LDLLEG 263
+ G
Sbjct: 292 WQTVVG 297
Score = 50.4 bits (115), Expect = 3e-05
Identities = 52/248 (20%), Positives = 101/248 (40%), Gaps = 11/248 (4%)
Query: 61 GHDEAVMDVTFSSS---GKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDG 117
GH V+D+ FS G ++ SA +D + G F H V + D
Sbjct: 12 GHTRPVVDLAFSDITPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 118 SKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
+K TA+ D K+W + + + H + V+ + D + + + DK ++++L+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMT-LAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 178 SGECIHTYKDLKGH--GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
E K++ GH G+ A S ++ V+L+D T V+ + N +V+
Sbjct: 131 KPEA--EPKEISGHTSGIKKALWCSEDKQILSADDKTVRLWDHATMTEVKSLNF-NMSVS 187
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ P G IL + + + PI + +N+ + P + + G+D
Sbjct: 188 SMEYIPEGE-ILVITYGRSIAFHSAVSLDPIKSFEA-PATINSASLHPEKEFLVAGGEDF 245
Query: 296 LVFIWKTN 303
++ + N
Sbjct: 246 KLYKYDYN 253
>BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61
protein.
Length = 305
Score = 97.9 bits (233), Expect = 2e-19
Identities = 74/297 (24%), Positives = 131/297 (44%), Gaps = 12/297 (4%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQ----IATSSLDNSVLLWDLRGTM--RSYRFQGHDEAV 66
L KQ + H +AI ++ + N ++ + T SLD+ V +W R + +GH V
Sbjct: 8 LFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGV 67
Query: 67 MDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
+ V S + AS+S D +R+W A ++ FS D + T +
Sbjct: 68 VSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHV 127
Query: 127 KVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
V ++ K S ++ S DG +AS + D ++++ +G+ +HT
Sbjct: 128 GKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT-- 185
Query: 187 DLKGHGL---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSG 243
L+GH + L + P + A+ G +K+YD++ NL S H V VA P
Sbjct: 186 -LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDD 244
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
++ +++S D +K+ D+ + T H V V ++ G S GDD+ + I+
Sbjct: 245 THFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 97.9 bits (233), Expect = 2e-19
Identities = 46/191 (24%), Positives = 90/191 (47%)
Query: 27 LYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKT 86
L ++P+ Q +AT + V ++ + + Y + ++ + +S GKY+AS + D
Sbjct: 112 LAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGI 171
Query: 87 VRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGH 146
+ I+ + H+ +RS+ FS D ++TASDD +K++ + GH
Sbjct: 172 INIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGH 231
Query: 147 TNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAV 206
+WV D + S S DKS K+W++ + C+HT+ D + + ++ +G +
Sbjct: 232 ASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVS 291
Query: 207 ATSHGNVKLYD 217
+ +YD
Sbjct: 292 VGDDQEIHIYD 302
Score = 88.2 bits (209), Expect = 1e-16
Identities = 55/213 (25%), Positives = 97/213 (45%), Gaps = 6/213 (2%)
Query: 102 KAHSQTVRSVQFSSDGSK----IITASDDKVVKLWSTHKHKFIS--SFVGHTNWVRCARM 155
+AH + SV + ++ + ++T S D +VK+W + S GH V +
Sbjct: 13 QAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDI 72
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKL 215
S+ I AS S D +LW+L++G+ I + LA+ P Y+A T G V +
Sbjct: 73 SHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNI 132
Query: 216 YDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGP 275
+ + + + + +A P G Y+ + + DG + I D+ G + TL GH P
Sbjct: 133 FGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMP 192
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLS 308
+ ++ FSP +A DD + I+ +L+
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDVQHANLA 225
Score = 84.2 bits (199), Expect = 2e-15
Identities = 53/247 (21%), Positives = 108/247 (43%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L+ L+GH+ + ++ + A+SSLD + LWDL + + FS
Sbjct: 56 LQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFS 115
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+Y+A+ + V I+ + + S+ +S DG + + + D ++ ++
Sbjct: 116 PDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + + GH +R S D ++ + SDD K++++ T
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWV 235
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
L++A+ P + ++S +VK++D+ T V + H + V V + +GS I++ D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 253 GKMKILD 259
++ I D
Sbjct: 296 QEIHIYD 302
>AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21101 fis, clone CAS04682. ).
Length = 305
Score = 97.9 bits (233), Expect = 2e-19
Identities = 74/297 (24%), Positives = 131/297 (44%), Gaps = 12/297 (4%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQ----IATSSLDNSVLLWDLRGTM--RSYRFQGHDEAV 66
L KQ + H +AI ++ + N ++ + T SLD+ V +W R + +GH V
Sbjct: 8 LFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGV 67
Query: 67 MDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
+ V S + AS+S D +R+W A ++ FS D + T +
Sbjct: 68 VSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHV 127
Query: 127 KVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
V ++ K S ++ S DG +AS + D ++++ +G+ +HT
Sbjct: 128 GKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT-- 185
Query: 187 DLKGHGL---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSG 243
L+GH + L + P + A+ G +K+YD++ NL S H V VA P
Sbjct: 186 -LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDD 244
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
++ +++S D +K+ D+ + T H V V ++ G S GDD+ + I+
Sbjct: 245 THFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 97.9 bits (233), Expect = 2e-19
Identities = 46/191 (24%), Positives = 90/191 (47%)
Query: 27 LYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKT 86
L ++P+ Q +AT + V ++ + + Y + ++ + +S GKY+AS + D
Sbjct: 112 LAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGI 171
Query: 87 VRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGH 146
+ I+ + H+ +RS+ FS D ++TASDD +K++ + GH
Sbjct: 172 INIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGH 231
Query: 147 TNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAV 206
+WV D + S S DKS K+W++ + C+HT+ D + + ++ +G +
Sbjct: 232 ASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVS 291
Query: 207 ATSHGNVKLYD 217
+ +YD
Sbjct: 292 VGDDQEIHIYD 302
Score = 88.2 bits (209), Expect = 1e-16
Identities = 55/213 (25%), Positives = 97/213 (45%), Gaps = 6/213 (2%)
Query: 102 KAHSQTVRSVQFSSDGSK----IITASDDKVVKLWSTHKHKFIS--SFVGHTNWVRCARM 155
+AH + SV + ++ + ++T S D +VK+W + S GH V +
Sbjct: 13 QAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDI 72
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKL 215
S+ I AS S D +LW+L++G+ I + LA+ P Y+A T G V +
Sbjct: 73 SHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNI 132
Query: 216 YDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGP 275
+ + + + + +A P G Y+ + + DG + I D+ G + TL GH P
Sbjct: 133 FGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMP 192
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLS 308
+ ++ FSP +A DD + I+ +L+
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDVQHANLA 225
Score = 84.2 bits (199), Expect = 2e-15
Identities = 53/247 (21%), Positives = 108/247 (43%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L+ L+GH+ + ++ + A+SSLD + LWDL + + FS
Sbjct: 56 LQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFS 115
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+Y+A+ + V I+ + + S+ +S DG + + + D ++ ++
Sbjct: 116 PDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + + GH +R S D ++ + SDD K++++ T
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWV 235
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
L++A+ P + ++S +VK++D+ T V + H + V V + +GS I++ D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 253 GKMKILD 259
++ I D
Sbjct: 296 QEIHIYD 302
>AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 97.9 bits (233), Expect = 2e-19
Identities = 67/256 (26%), Positives = 120/256 (46%), Gaps = 16/256 (6%)
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H +AV FS G+ +AS DKT++++ KAH V FS+D I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDSG 179
T S DK VK+W++ + + ++ H+ V C +N ++A+ S D KLW+L+
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI------RTHNLVQYYSIHNEA 233
EC +T H + P +A ++ G +KL+D ++ N+ Q++ +
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 793
Query: 234 VTQVAI-------HPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD 286
+ + G+ I+ A+K+ K+ + + + GH V+ V FSP G
Sbjct: 794 QGDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVTDCRGHLSWVHGVMFSPDGS 852
Query: 287 TFSSAGDDKLVFIWKT 302
+F ++ DD+ + +W+T
Sbjct: 853 SFLTSSDDQTIRLWET 868
Score = 88.6 bits (210), Expect = 9e-17
Identities = 62/256 (24%), Positives = 118/256 (46%), Gaps = 16/256 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 670
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---------ECIHTY 185
++ + ++ GHTN V R S D ++ASCS D + KLW+ S +
Sbjct: 731 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 790
Query: 186 KDLKGHGLHL----AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+D +G + +W G + VA + + L++ + + V H V V P
Sbjct: 791 EDPQGDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVTDCRGHLSWVHGVMFSP 849
Query: 242 SGSYILTASKDGKMKI 257
GS LT+S D +++
Sbjct: 850 DGSSFLTSSDDQTIRL 865
Score = 83.0 bits (196), Expect = 5e-15
Identities = 68/278 (24%), Positives = 117/278 (42%), Gaps = 19/278 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+AT S D + LWDL GH +V FS K +AS S D T+++W T
Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSA 775
Query: 96 GSTGMFKAHS-------------QTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
V+ +S+DG++I+ A+ +K+ LW+T ++
Sbjct: 776 NERKSINVKQFFLNLEDPQGDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVTD 834
Query: 143 FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGC 202
GH +WV S DGS + SDD++ +LW C ++ LK + + + +
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNSAVMLK-QEVDVVFQENEV 892
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
V ++L + RT + Y + V+ + P YI ++G ++IL+L+
Sbjct: 893 MVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 263 GHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ H V + F+ T S+ DD + +W
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 987
Score = 75.8 bits (178), Expect = 7e-13
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 2/160 (1%)
Query: 102 KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
+ H+ V FS DG +I + DK ++++ + + H + V C S D
Sbjct: 612 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN--VKLYDIR 219
IA+CS DK K+WN +GE +HTY + + S ++ +AT + +KL+D+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
H +V P + + S DG +K+ D
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 927 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 986 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1161
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1162 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1203
Score = 64.1 bits (149), Expect = 2e-09
Identities = 62/271 (22%), Positives = 123/271 (45%), Gaps = 20/271 (7%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRF-------QGHDEAV 66
GH N++ ++P+D+ +A+ S D ++ LWD R ++ +F QG E +
Sbjct: 741 GHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQGDMEVI 800
Query: 67 MDV-TFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASD 125
+ ++S+ G + A+++K + +W + H V V FS DGS +T+SD
Sbjct: 801 VKCCSWSADGARIMVAAKNK-IFLWNTDSRSKVTDCRGHLSWVHGVMFSPDGSSFLTSSD 859
Query: 126 DKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
D+ ++LW T K +S V V N+ ++A + +L N +G+ I
Sbjct: 860 DQTIRLWET-KKVCKNSAVMLKQEVDVVFQENEVMVLA-VDHIRRLQLINGRTGQ-IDYL 916
Query: 186 KDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSY 245
+ + L+ H Y+A +G +++ ++ + + Q H + V +
Sbjct: 917 TEAQVSCCCLSPHLQ--YIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKT 974
Query: 246 ILTASKDGKMKILDLLEGHPIFTLSGHNGPV 276
++++S D ++++ + IF L GH V
Sbjct: 975 LISSSDDAEIQVWNWQLDKCIF-LRGHQETV 1004
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 893
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 894 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1005
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1006 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1065
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1066 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 61.3 bits (142), Expect = 2e-08
Identities = 56/233 (24%), Positives = 103/233 (44%), Gaps = 24/233 (10%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
K T E L ++K H++ + ++ +D+ IAT S+D V +W+ + + H E
Sbjct: 643 KAETGEKLL--EIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSE 700
Query: 65 AVMDVTFSSSGKY--MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
V F++S + +A+ S D +++W H+ +V +FS D + +
Sbjct: 701 QVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLAS 760
Query: 123 ASDDKVVKLW---STHKHKFISSFVGHTNW----------VRCARMSNDGSIIASCSDDK 169
S D +KLW S ++ K I+ N V+C S DG+ I + +K
Sbjct: 761 CSADGTLKLWDATSANERKSINVKQFFLNLEDPQGDMEVIVKCCSWSADGARIMVAAKNK 820
Query: 170 STKLWNLDSGECIHTYKDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIR 219
LWN DS + D +GH +H + + P G ++ ++L++ +
Sbjct: 821 -IFLWNTDSRSKV---TDCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETK 869
>AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination
protein REC14 protein.
Length = 305
Score = 97.9 bits (233), Expect = 2e-19
Identities = 74/297 (24%), Positives = 131/297 (44%), Gaps = 12/297 (4%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQ----IATSSLDNSVLLWDLRGTM--RSYRFQGHDEAV 66
L KQ + H +AI ++ + N ++ + T SLD+ V +W R + +GH V
Sbjct: 8 LFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGV 67
Query: 67 MDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
+ V S + AS+S D +R+W A ++ FS D + T +
Sbjct: 68 VSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHV 127
Query: 127 KVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
V ++ K S ++ S DG +AS + D ++++ +G+ +HT
Sbjct: 128 GKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT-- 185
Query: 187 DLKGHGL---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSG 243
L+GH + L + P + A+ G +K+YD++ NL S H V VA P
Sbjct: 186 -LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDD 244
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
++ +++S D +K+ D+ + T H V V ++ G S GDD+ + I+
Sbjct: 245 THFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 97.9 bits (233), Expect = 2e-19
Identities = 46/191 (24%), Positives = 90/191 (47%)
Query: 27 LYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKT 86
L ++P+ Q +AT + V ++ + + Y + ++ + +S GKY+AS + D
Sbjct: 112 LAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGI 171
Query: 87 VRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGH 146
+ I+ + H+ +RS+ FS D ++TASDD +K++ + GH
Sbjct: 172 INIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGH 231
Query: 147 TNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAV 206
+WV D + S S DKS K+W++ + C+HT+ D + + ++ +G +
Sbjct: 232 ASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVS 291
Query: 207 ATSHGNVKLYD 217
+ +YD
Sbjct: 292 VGDDQEIHIYD 302
Score = 88.2 bits (209), Expect = 1e-16
Identities = 55/213 (25%), Positives = 97/213 (45%), Gaps = 6/213 (2%)
Query: 102 KAHSQTVRSVQFSSDGSK----IITASDDKVVKLWSTHKHKFIS--SFVGHTNWVRCARM 155
+AH + SV + ++ + ++T S D +VK+W + S GH V +
Sbjct: 13 QAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDI 72
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKL 215
S+ I AS S D +LW+L++G+ I + LA+ P Y+A T G V +
Sbjct: 73 SHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNI 132
Query: 216 YDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGP 275
+ + + + + +A P G Y+ + + DG + I D+ G + TL GH P
Sbjct: 133 FGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMP 192
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLS 308
+ ++ FSP +A DD + I+ +L+
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDVQHANLA 225
Score = 84.2 bits (199), Expect = 2e-15
Identities = 53/247 (21%), Positives = 108/247 (43%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L+ L+GH+ + ++ + A+SSLD + LWDL + + FS
Sbjct: 56 LQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFS 115
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+Y+A+ + V I+ + + S+ +S DG + + + D ++ ++
Sbjct: 116 PDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + + GH +R S D ++ + SDD K++++ T
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWV 235
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
L++A+ P + ++S +VK++D+ T V + H + V V + +GS I++ D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 253 GKMKILD 259
++ I D
Sbjct: 296 QEIHIYD 302
>AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta
subunit-like protein protein.
Length = 305
Score = 97.9 bits (233), Expect = 2e-19
Identities = 74/297 (24%), Positives = 131/297 (44%), Gaps = 12/297 (4%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQ----IATSSLDNSVLLWDLRGTM--RSYRFQGHDEAV 66
L KQ + H +AI ++ + N ++ + T SLD+ V +W R + +GH V
Sbjct: 8 LFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGV 67
Query: 67 MDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
+ V S + AS+S D +R+W A ++ FS D + T +
Sbjct: 68 VSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHV 127
Query: 127 KVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
V ++ K S ++ S DG +AS + D ++++ +G+ +HT
Sbjct: 128 GKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT-- 185
Query: 187 DLKGHGL---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSG 243
L+GH + L + P + A+ G +K+YD++ NL S H V VA P
Sbjct: 186 -LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDD 244
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
++ +++S D +K+ D+ + T H V V ++ G S GDD+ + I+
Sbjct: 245 THFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 97.9 bits (233), Expect = 2e-19
Identities = 46/191 (24%), Positives = 90/191 (47%)
Query: 27 LYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKT 86
L ++P+ Q +AT + V ++ + + Y + ++ + +S GKY+AS + D
Sbjct: 112 LAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGI 171
Query: 87 VRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGH 146
+ I+ + H+ +RS+ FS D ++TASDD +K++ + GH
Sbjct: 172 INIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGH 231
Query: 147 TNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAV 206
+WV D + S S DKS K+W++ + C+HT+ D + + ++ +G +
Sbjct: 232 ASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVS 291
Query: 207 ATSHGNVKLYD 217
+ +YD
Sbjct: 292 VGDDQEIHIYD 302
Score = 88.2 bits (209), Expect = 1e-16
Identities = 55/213 (25%), Positives = 97/213 (45%), Gaps = 6/213 (2%)
Query: 102 KAHSQTVRSVQFSSDGSK----IITASDDKVVKLWSTHKHKFIS--SFVGHTNWVRCARM 155
+AH + SV + ++ + ++T S D +VK+W + S GH V +
Sbjct: 13 QAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDI 72
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKL 215
S+ I AS S D +LW+L++G+ I + LA+ P Y+A T G V +
Sbjct: 73 SHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNI 132
Query: 216 YDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGP 275
+ + + + + +A P G Y+ + + DG + I D+ G + TL GH P
Sbjct: 133 FGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMP 192
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLS 308
+ ++ FSP +A DD + I+ +L+
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDVQHANLA 225
Score = 84.2 bits (199), Expect = 2e-15
Identities = 53/247 (21%), Positives = 108/247 (43%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L+ L+GH+ + ++ + A+SSLD + LWDL + + FS
Sbjct: 56 LQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFS 115
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+Y+A+ + V I+ + + S+ +S DG + + + D ++ ++
Sbjct: 116 PDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + + GH +R S D ++ + SDD K++++ T
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWV 235
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
L++A+ P + ++S +VK++D+ T V + H + V V + +GS I++ D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 253 GKMKILD 259
++ I D
Sbjct: 296 QEIHIYD 302
>AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease
activating factor-1 protein.
Length = 1171
Score = 97.5 bits (232), Expect = 2e-19
Identities = 67/256 (26%), Positives = 120/256 (46%), Gaps = 16/256 (6%)
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H +AV FS G+ +AS DKT++++ KAH V FS+D I
Sbjct: 622 HTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 681
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDSG 179
T S DK VK+W++ + + ++ H+ V C +N ++A+ S D KLW+L+
Sbjct: 682 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 741
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI------RTHNLVQYYSIHNEA 233
EC +T H + P +A ++ G +KL+D ++ N+ Q++ +
Sbjct: 742 ECRNTMFGHTNSVNHCRFSPDDKPLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 801
Query: 234 VTQVAI-------HPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD 286
+ + G+ I+ A+K+ K+ + + + GH V+ V FSP G
Sbjct: 802 QEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGS 860
Query: 287 TFSSAGDDKLVFIWKT 302
+F ++ DD+ + +W+T
Sbjct: 861 SFLTSSDDQTIRLWET 876
Score = 86.6 bits (205), Expect = 4e-16
Identities = 62/256 (24%), Positives = 118/256 (46%), Gaps = 16/256 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 619 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 678
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 679 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 738
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN V R S D +ASCS D + KLW+ S + I+
Sbjct: 739 NQKECRNTMFGHTNSVNHCRFSPDDKPLASCSADGTLKLWDATSANERKSINVKQFFLNL 798
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+D++ +W G + VA + + L++ + + V H V V P
Sbjct: 799 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSP 857
Query: 242 SGSYILTASKDGKMKI 257
GS LT+S D +++
Sbjct: 858 DGSSFLTSSDDQTIRL 873
Score = 82.2 bits (194), Expect = 8e-15
Identities = 68/278 (24%), Positives = 117/278 (42%), Gaps = 19/278 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+AT S D + LWDL GH +V FS K +AS S D T+++W T
Sbjct: 724 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKPLASCSADGTLKLWDATSA 783
Query: 96 GSTGMFKAHS-------------QTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
V+ +S+DG++I+ A+ +K+ LW+T ++
Sbjct: 784 NERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVAD 842
Query: 143 FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGC 202
GH +WV S DGS + SDD++ +LW C ++ LK + + + +
Sbjct: 843 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNSAVMLK-QEVDVVFQENEV 900
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
V ++L + RT + Y + V+ + P YI ++G ++IL+L+
Sbjct: 901 MVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 957
Query: 263 GHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ H V + F+ T S+ DD + +W
Sbjct: 958 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 995
Score = 77.8 bits (183), Expect = 2e-13
Identities = 57/240 (23%), Positives = 112/240 (46%), Gaps = 10/240 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 935 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 993
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 994 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1051
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL--KGHGLHLAWHPSGCY--- 203
V +S+D + +S S DK+ K+WN+ +GE +H L +G H W C+
Sbjct: 1052 TVLSCDISHDATKFSSTSADKTAKIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPD 1111
Query: 204 -VAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
+ ++ G +K +++ T Q + + + ++ + P +T G + IL LE
Sbjct: 1112 GKMLISAGGYIKWWNVVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQTLE 1171
Score = 74.9 bits (176), Expect = 1e-12
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 2/160 (1%)
Query: 102 KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
+ H+ V FS DG +I + DK ++++ + + H + V C S D
Sbjct: 620 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 679
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN--VKLYDIR 219
IA+CS DK K+WN +GE +HTY + + S ++ +AT + +KL+D+
Sbjct: 680 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 739
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
H +V P + + S DG +K+ D
Sbjct: 740 QKECRNTMFGHTNSVNHCRFSPDDKPLASCSADGTLKLWD 779
Score = 61.7 bits (143), Expect = 1e-08
Identities = 56/233 (24%), Positives = 103/233 (44%), Gaps = 24/233 (10%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
K T E L ++K H++ + ++ +D+ IAT S+D V +W+ + + H E
Sbjct: 651 KAETGEKLL--EIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSE 708
Query: 65 AVMDVTFSSSGKY--MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
V F++S + +A+ S D +++W H+ +V +FS D + +
Sbjct: 709 QVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKPLAS 768
Query: 123 ASDDKVVKLW---STHKHKFISSFVGHTNW----------VRCARMSNDGSIIASCSDDK 169
S D +KLW S ++ K I+ N V+C S DG+ I + +K
Sbjct: 769 CSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK 828
Query: 170 STKLWNLDSGECIHTYKDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIR 219
LWN DS + D +GH +H + + P G ++ ++L++ +
Sbjct: 829 -IFLWNTDSRSKV---ADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETK 877
Score = 55.2 bits (127), Expect = 1e-06
Identities = 68/313 (21%), Positives = 122/313 (38%), Gaps = 24/313 (7%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 844 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 901
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 902 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 957
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 958 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1013
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGK 254
+ + G VK+++I T N + + H V I + + S D
Sbjct: 1014 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1073
Query: 255 MKILDLLEG---HPIFTLS-----GHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTD 306
KI ++ G H LS H G V + FSP G SAG W T
Sbjct: 1074 AKIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGG---YIKWWNVVTG 1130
Query: 307 LSSESKENEGQNM 319
SS++ G N+
Sbjct: 1131 ESSQTFYTNGTNL 1143
>AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 97.5 bits (232), Expect = 2e-19
Identities = 67/256 (26%), Positives = 119/256 (46%), Gaps = 16/256 (6%)
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H +AV FS G+ +AS DKT +++ KAH V FS+D I
Sbjct: 614 HTDAVYHACFSEDGQRIASCGADKTFQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDSG 179
T S DK VK+W++ + + ++ H+ V C +N ++A+ S D KLW+L+
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI------RTHNLVQYYSIHNEA 233
EC +T H + P +A ++ G +KL+D ++ N+ Q++ +
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 793
Query: 234 VTQVAI-------HPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD 286
+ + G+ I+ A+K+ K+ + + + GH V+ V FSP G
Sbjct: 794 QEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGS 852
Query: 287 TFSSAGDDKLVFIWKT 302
+F ++ DD+ + +W+T
Sbjct: 853 SFLTSSDDQTIRLWET 868
Score = 87.8 bits (208), Expect = 2e-16
Identities = 62/256 (24%), Positives = 118/256 (46%), Gaps = 16/256 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D + ++ + + H++ V+ FS+ +
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTFQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 670
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---ECIHT------- 184
++ + ++ GHTN V R S D ++ASCS D + KLW+ S + I+
Sbjct: 731 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL 790
Query: 185 ---YKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHP 241
+D++ +W G + VA + + L++ + + V H V V P
Sbjct: 791 EDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 242 SGSYILTASKDGKMKI 257
GS LT+S D +++
Sbjct: 850 DGSSFLTSSDDQTIRL 865
Score = 83.0 bits (196), Expect = 5e-15
Identities = 68/278 (24%), Positives = 117/278 (42%), Gaps = 19/278 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+AT S D + LWDL GH +V FS K +AS S D T+++W T
Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSA 775
Query: 96 GSTGMFKAHS-------------QTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
V+ +S+DG++I+ A+ +K+ LW+T ++
Sbjct: 776 NERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIF-LWNTDSRSKVAD 834
Query: 143 FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGC 202
GH +WV S DGS + SDD++ +LW C ++ LK + + + +
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNSAVMLK-QEVDVVFQENEV 892
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
V ++L + RT + Y + V+ + P YI ++G ++IL+L+
Sbjct: 893 MVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 263 GHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ H V + F+ T S+ DD + +W
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 987
Score = 74.9 bits (176), Expect = 1e-12
Identities = 42/160 (26%), Positives = 70/160 (43%), Gaps = 2/160 (1%)
Query: 102 KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
+ H+ V FS DG +I + DK +++ + + H + V C S D
Sbjct: 612 RPHTDAVYHACFSEDGQRIASCGADKTFQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN--VKLYDIR 219
IA+CS DK K+WN +GE +HTY + + S ++ +AT + +KL+D+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
H +V P + + S DG +K+ D
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 927 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 986 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1161
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1162 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1203
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 893
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 894 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1005
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1006 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1065
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1066 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 61.3 bits (142), Expect = 2e-08
Identities = 56/233 (24%), Positives = 103/233 (44%), Gaps = 24/233 (10%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
K T E L ++K H++ + ++ +D+ IAT S+D V +W+ + + H E
Sbjct: 643 KAETGEKLL--EIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSE 700
Query: 65 AVMDVTFSSSGKY--MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
V F++S + +A+ S D +++W H+ +V +FS D + +
Sbjct: 701 QVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLAS 760
Query: 123 ASDDKVVKLW---STHKHKFISSFVGHTNW----------VRCARMSNDGSIIASCSDDK 169
S D +KLW S ++ K I+ N V+C S DG+ I + +K
Sbjct: 761 CSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNK 820
Query: 170 STKLWNLDSGECIHTYKDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIR 219
LWN DS + D +GH +H + + P G ++ ++L++ +
Sbjct: 821 -IFLWNTDSRSKV---ADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETK 869
>AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating
factor-1 protein.
Length = 1205
Score = 97.1 bits (231), Expect = 3e-19
Identities = 67/256 (26%), Positives = 120/256 (46%), Gaps = 16/256 (6%)
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H +AV FS G+ +AS DKT++++ KAH V FS+D I
Sbjct: 614 HTDAVYRACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIA 673
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGS--IIASCSDDKSTKLWNLDSG 179
T S DK VK+W++ + + ++ H+ V C +N ++A+ S D KLW+L+
Sbjct: 674 TCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 180 ECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI------RTHNLVQYYSIHNEA 233
EC +T H + P +A ++ G +KL+D ++ N+ Q++ +
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 793
Query: 234 VTQVAI-------HPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD 286
+ + G+ I+ A+K+ K+ + + + GH V+ V FSP G
Sbjct: 794 QEDMGVIVKCCSWSADGARIMVAAKN-KIFLWNTDLRSKVADCRGHLSWVHGVMFSPDGS 852
Query: 287 TFSSAGDDKLVFIWKT 302
+F ++ DD+ + +W+T
Sbjct: 853 SFLTSSDDQTIRLWET 868
Score = 87.8 bits (208), Expect = 2e-16
Identities = 63/257 (24%), Positives = 118/257 (45%), Gaps = 18/257 (7%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
++ H +A+ ++ + Q+IA+ D ++ ++ + + H++ V+ FS+ +
Sbjct: 611 VRPHTDAVYRACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDR 670
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWST 134
++A+ S DK V+IW + HS+ V F++ ++ T S D +KLW
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 135 HKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
++ + ++ GHTN V R S D ++ASCS D + KLW+ S + ++K L+
Sbjct: 731 NQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSI-NVKQFFLN 789
Query: 195 L--------------AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIH 240
L +W G + VA + + L++ + V H V V
Sbjct: 790 LEDPQEDMGVIVKCCSWSADGARIMVAAKN-KIFLWNTDLRSKVADCRGHLSWVHGVMFS 848
Query: 241 PSGSYILTASKDGKMKI 257
P GS LT+S D +++
Sbjct: 849 PDGSSFLTSSDDQTIRL 865
Score = 82.2 bits (194), Expect = 8e-15
Identities = 68/278 (24%), Positives = 117/278 (42%), Gaps = 19/278 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+AT S D + LWDL GH +V FS K +AS S D T+++W T
Sbjct: 716 LATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSA 775
Query: 96 GSTGMFKAHS-------------QTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
V+ +S+DG++I+ A+ +K+ LW+T ++
Sbjct: 776 NERKSINVKQFFLNLEDPQEDMGVIVKCCSWSADGARIMVAAKNKIF-LWNTDLRSKVAD 834
Query: 143 FVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGC 202
GH +WV S DGS + SDD++ +LW C ++ LK + + + +
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK-VCKNSAVMLK-QEVDVVFQENEV 892
Query: 203 YVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLE 262
V ++L + RT + Y + V+ + P YI ++G ++IL+L+
Sbjct: 893 MVLAVDHIRRLQLINGRT-GQIDY--LTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 263 GHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ H V + F+ T S+ DD + +W
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVW 987
Score = 75.8 bits (178), Expect = 7e-13
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 2/160 (1%)
Query: 102 KAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
+ H+ V FS DG +I + DK ++++ + + H + V C S D
Sbjct: 612 RPHTDAVYRACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN--VKLYDIR 219
IA+CS DK K+WN +GE +HTY + + S ++ +AT + +KL+D+
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
H +V P + + S DG +K+ D
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/282 (20%), Positives = 128/282 (45%), Gaps = 14/282 (4%)
Query: 30 NPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
+P+ Q IA + ++ + +L + RFQ H + V + F++ K + S+S D ++
Sbjct: 927 SPHLQYIAFGDENGAIEILELVNNRIFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQ 985
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
+W + + H +TV+ + + S++++ S D VK+W+ FV H
Sbjct: 986 VWNWQLDKCI-FLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKEKDFVCHQG 1043
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V +S+D + +S S DK+ K+W+ D +H + G A+ +A
Sbjct: 1044 TVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 209 SHGNVKLYDIRTHNLV--------QYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
+G ++++++ L+ + + H VT + P G +++A G +K ++
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--GYIKWWNV 1161
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
+ G T + + ++ SP T+ + + +++I +T
Sbjct: 1162 VTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQT 1203
Score = 63.7 bits (148), Expect = 3e-09
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (5%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY 77
+GH + + + ++P+ TSS D ++ LW+ + ++ E +DV F +
Sbjct: 836 RGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQE--VDVVFQENEVM 893
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDK-VVKLWSTHK 136
+ + + +++ + G TG ++ S S + I D+ +++
Sbjct: 894 VLAVDHIRRLQL----INGRTGQIDYLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVN 949
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
++ S H V + + D + S SDD ++WN +CI L+GH +
Sbjct: 950 NRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIF----LRGHQETVK 1005
Query: 197 WHP--SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAI-HPSGSYILT-ASKD 252
+ + G VK+++I T N + + H V I H + + T A K
Sbjct: 1006 DFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKT 1065
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDL 307
K+ DLL P+ L GHNG V FS ++ D+ + IW + +L
Sbjct: 1066 AKIWSFDLL--LPLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 58.8 bits (136), Expect = 9e-08
Identities = 55/233 (23%), Positives = 102/233 (43%), Gaps = 24/233 (10%)
Query: 5 KVTTPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDE 64
K T E L ++K H++ + ++ +D+ IAT S+D V +W+ + + H E
Sbjct: 643 KAETGEKLL--EIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSE 700
Query: 65 AVMDVTFSSSGKY--MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
V F++S + +A+ S D +++W H+ +V +FS D + +
Sbjct: 701 QVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLAS 760
Query: 123 ASDDKVVKLW---STHKHKFISSFVGHTNW----------VRCARMSNDGSIIASCSDDK 169
S D +KLW S ++ K I+ N V+C S DG+ I + +K
Sbjct: 761 CSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMGVIVKCCSWSADGARIMVAAKNK 820
Query: 170 STKLWNLDSGECIHTYKDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIR 219
LWN D + D +GH +H + + P G ++ ++L++ +
Sbjct: 821 -IFLWNTDLRSKV---ADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETK 869
>BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 413 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 469
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR VQ+ DG ++++ + D +VK+
Sbjct: 470 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKV 525
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 526 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 580
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 581 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 638
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 639 TSSDDGTVKLWDLKTGEFIRNL 660
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 13/206 (6%)
Query: 97 STGMFKAHSQ-TVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
S + K H + +QF G++I++ SDD +K+WS K + + VGHT V ++M
Sbjct: 372 SPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM 429
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVK 214
+ +II S S D++ K+WN ++GECIHT L GH + H V + ++
Sbjct: 430 RD--NIIISGSTDRTLKVWNAETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLR 484
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
++DI T + H AV + G +++ + D +K+ D + TL GH
Sbjct: 485 VWDIETGQCLHVLMGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN 542
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ F G S D + +W
Sbjct: 543 RVYSLQFD--GIHVVSGSLDTSIRVW 566
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 497 LMGHVAAVRCVQYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 552
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 553 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 610
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 611 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 667
>BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 413 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 469
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR VQ+ DG ++++ + D +VK+
Sbjct: 470 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKV 525
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 526 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 580
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 581 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 638
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 639 TSSDDGTVKLWDLKTGEFIRNL 660
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 13/206 (6%)
Query: 97 STGMFKAHSQ-TVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
S + K H + +QF G++I++ SDD +K+WS K + + VGHT V ++M
Sbjct: 372 SPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM 429
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVK 214
+ +II S S D++ K+WN ++GECIHT L GH + H V + ++
Sbjct: 430 RD--NIIISGSTDRTLKVWNAETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLR 484
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
++DI T + H AV + G +++ + D +K+ D + TL GH
Sbjct: 485 VWDIETGQCLHVLMGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN 542
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ F G S D + +W
Sbjct: 543 RVYSLQFD--GIHVVSGSLDTSIRVW 566
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 497 LMGHVAAVRCVQYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 552
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 553 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 610
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 611 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 667
>BC035409-1|AAH35409.1| 808|Homo sapiens transducin (beta)-like 3
protein.
Length = 808
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/301 (24%), Positives = 133/301 (44%), Gaps = 19/301 (6%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF--SSSGKY 77
H + + ++P +AT D +V +WD+ ++ F+G V V F +
Sbjct: 108 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLL 167
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW---ST 134
+ S++ D +R+W + AH V S+ FS+DG ++++ DK+ +W S
Sbjct: 168 LFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSC 227
Query: 135 HKHKFISSFVGHTNWVRCAR-------MSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
+ + F V + + G + D + ++W SG+C++T
Sbjct: 228 QATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQ 287
Query: 188 LKGHGLHLAW----HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA-IHPS 242
G G L H +G V AT+ N+ LY+ R+ L + ++ ++E V V + P
Sbjct: 288 PPGPGQELTHCTLAHTAGV-VLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPE 346
Query: 243 GSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
S+++ AS +K+ +L + L GH V A++ G F+S D+ V IW+
Sbjct: 347 DSHVVVASNSPCLKVFEL-QTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRM 405
Query: 303 N 303
N
Sbjct: 406 N 406
Score = 87.8 bits (208), Expect = 2e-16
Identities = 70/334 (20%), Positives = 143/334 (42%), Gaps = 22/334 (6%)
Query: 13 LKKQLKGHKNAITAL-YYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
L+KQ G+ + + + P D + +S + +++L+ T GH + V+ +
Sbjct: 326 LQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQ-TSACQILHGHTDIVLALDV 384
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGST---GMFKAHSQTVRSVQFSS-DGSKIITASDDK 127
G AS ++D++VRIW G H+ +V +V S S ++T S D
Sbjct: 385 FRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDC 444
Query: 128 VVKLWSTHKHKFISSFVG---------------HTNWVRCARMSNDGSIIASCSDDKSTK 172
VKLW K + H + ++ + ++A+ S D++ K
Sbjct: 445 TVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAK 504
Query: 173 LWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE 232
LW L + + + + + + P +A A++ G +KL+ ++ + ++ + H+
Sbjct: 505 LWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDA 564
Query: 233 AVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+V +VA G+ +L++ DG +K+ + + TL H V ++ S D +
Sbjct: 565 SVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGA 624
Query: 293 DDKLVFIWKTNFTDLSSESKENEGQNMITGQRHL 326
D V +WK + T+ ++ + + Q+ L
Sbjct: 625 SDSRVILWK-DVTEAEQAEEQARQEEQVVRQQEL 657
Score = 74.9 bits (176), Expect = 1e-12
Identities = 68/287 (23%), Positives = 126/287 (43%), Gaps = 25/287 (8%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF-SSSGKYMASASRDKTVRIWVPTV 94
+ T++ D+++LL++ R +F G+ E V+DV F ++ AS ++++
Sbjct: 307 VLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVF-ELQ 365
Query: 95 TGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH---KFISSFVGHTN--- 148
T + + H+ V ++ G + + D+ V++W +K ++ GHT+
Sbjct: 366 TSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVG 425
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNL-----------DSGECI---HTYKDLKGHGLH 194
V C+R+ S + + S D + KLW L D+G + T + ++
Sbjct: 426 TVCCSRLKE--SFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDIN 483
Query: 195 -LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDG 253
+A P+ +A + KL+ + L+ +S H + V P + TAS DG
Sbjct: 484 SVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADG 543
Query: 254 KMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+K+ L + + T GH+ V V F G S+G D LV +W
Sbjct: 544 TIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLW 590
Score = 68.1 bits (159), Expect = 1e-10
Identities = 36/124 (29%), Positives = 57/124 (45%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P+ L GH+ + + ++P DQ +AT+S D ++ LW L+ F+GHD +V+
Sbjct: 509 PQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLK 568
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V F S G + S+ D V++W AH V + S +T + D
Sbjct: 569 VAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSR 628
Query: 129 VKLW 132
V LW
Sbjct: 629 VILW 632
Score = 54.8 bits (126), Expect = 1e-06
Identities = 37/164 (22%), Positives = 70/164 (42%), Gaps = 3/164 (1%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKYMASAS 82
ITA +P+++ + T+S + W + G++ H V + F + +A+
Sbjct: 69 ITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLSKAIHTAPVATMAFDPTSTLLATGG 128
Query: 83 RDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWSTHKHKFI 140
D VR+W T F+ V V F D ++++ +++ D +++WS +
Sbjct: 129 CDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCL 188
Query: 141 SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
+ H + V S DG + S DK +W+L S + T
Sbjct: 189 AVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRT 232
Score = 52.0 bits (119), Expect = 1e-05
Identities = 35/149 (23%), Positives = 65/149 (43%), Gaps = 3/149 (2%)
Query: 155 MSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH-LAWHPSGCYVAVATSHGNV 213
+S D ++ + S W G K + + +A+ P+ +A G V
Sbjct: 74 LSPDNEVLVTASRALLLAQWAWQEGSVTRLSKAIHTAPVATMAFDPTSTLLATGGCDGAV 133
Query: 214 KLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL--TASKDGKMKILDLLEGHPIFTLSG 271
+++DI H ++ V VA HP + +L +++ D +++ L + + L+
Sbjct: 134 RVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTA 193
Query: 272 HNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
H V ++ FS G T S+G DK+ IW
Sbjct: 194 HYSAVTSLAFSADGHTMLSSGRDKICIIW 222
Score = 44.8 bits (101), Expect = 0.001
Identities = 57/281 (20%), Positives = 113/281 (40%), Gaps = 25/281 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR---FQGHDEAVM------ 67
L H +A+T+L ++ + + +S D ++WDL+ + F+ + AV+
Sbjct: 191 LTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPV 250
Query: 68 -DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFSSDGSKIIT 122
+ S G Y +A T+R+W +G +A Q + + ++T
Sbjct: 251 SQLGVKSPGLYFLTAGDQGTLRVW-EAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLT 309
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCAR-MSNDGSIIASCSDDKSTKLWNLDSGEC 181
A+ D + L+ + F G++ V R + + S + S+ K++ L + C
Sbjct: 310 ATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSAC 369
Query: 182 --IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAV-T 235
+H + D+ L L G A +V+++ + V S H +V T
Sbjct: 370 QILHGHTDIV---LALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGT 426
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPV 276
S+++T S+D +K+ L + + NGP+
Sbjct: 427 VCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPI 467
>BC014007-1|AAH14007.1| 808|Homo sapiens TBL3 protein protein.
Length = 808
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/301 (24%), Positives = 133/301 (44%), Gaps = 19/301 (6%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF--SSSGKY 77
H + + ++P +AT D +V +WD+ ++ F+G V V F +
Sbjct: 108 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLL 167
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW---ST 134
+ S++ D +R+W + AH V S+ FS+DG ++++ DK+ +W S
Sbjct: 168 LFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSC 227
Query: 135 HKHKFISSFVGHTNWVRCAR-------MSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
+ + F V + + G + D + ++W SG+C++T
Sbjct: 228 QATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQ 287
Query: 188 LKGHGLHLAW----HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA-IHPS 242
G G L H +G V AT+ N+ LY+ R+ L + ++ ++E V V + P
Sbjct: 288 PPGPGQELTHCTLAHTAGV-VLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPE 346
Query: 243 GSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
S+++ AS +K+ +L + L GH V A++ G F+S D+ V IW+
Sbjct: 347 DSHVVVASNSPCLKVFEL-QTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRM 405
Query: 303 N 303
N
Sbjct: 406 N 406
Score = 87.8 bits (208), Expect = 2e-16
Identities = 70/334 (20%), Positives = 143/334 (42%), Gaps = 22/334 (6%)
Query: 13 LKKQLKGHKNAITAL-YYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
L+KQ G+ + + + P D + +S + +++L+ T GH + V+ +
Sbjct: 326 LQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQ-TSACQILHGHTDIVLALDV 384
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGST---GMFKAHSQTVRSVQFSS-DGSKIITASDDK 127
G AS ++D++VRIW G H+ +V +V S S ++T S D
Sbjct: 385 FRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDC 444
Query: 128 VVKLWSTHKHKFISSFVG---------------HTNWVRCARMSNDGSIIASCSDDKSTK 172
VKLW K + H + ++ + ++A+ S D++ K
Sbjct: 445 TVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAK 504
Query: 173 LWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE 232
LW L + + + + + + P +A A++ G +KL+ ++ + ++ + H+
Sbjct: 505 LWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDA 564
Query: 233 AVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+V +VA G+ +L++ DG +K+ + + TL H V ++ S D +
Sbjct: 565 SVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGA 624
Query: 293 DDKLVFIWKTNFTDLSSESKENEGQNMITGQRHL 326
D V +WK + T+ ++ + + Q+ L
Sbjct: 625 SDSRVILWK-DVTEAEQAEEQARQEEQVVRQQEL 657
Score = 74.9 bits (176), Expect = 1e-12
Identities = 68/287 (23%), Positives = 126/287 (43%), Gaps = 25/287 (8%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF-SSSGKYMASASRDKTVRIWVPTV 94
+ T++ D+++LL++ R +F G+ E V+DV F ++ AS ++++
Sbjct: 307 VLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVF-ELQ 365
Query: 95 TGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH---KFISSFVGHTN--- 148
T + + H+ V ++ G + + D+ V++W +K ++ GHT+
Sbjct: 366 TSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVG 425
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNL-----------DSGECI---HTYKDLKGHGLH 194
V C+R+ S + + S D + KLW L D+G + T + ++
Sbjct: 426 TVCCSRLKE--SFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDIN 483
Query: 195 -LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDG 253
+A P+ +A + KL+ + L+ +S H + V P + TAS DG
Sbjct: 484 SVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADG 543
Query: 254 KMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+K+ L + + T GH+ V V F G S+G D LV +W
Sbjct: 544 TIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLW 590
Score = 68.1 bits (159), Expect = 1e-10
Identities = 36/124 (29%), Positives = 57/124 (45%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P+ L GH+ + + ++P DQ +AT+S D ++ LW L+ F+GHD +V+
Sbjct: 509 PQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLK 568
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V F S G + S+ D V++W AH V + S +T + D
Sbjct: 569 VAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSR 628
Query: 129 VKLW 132
V LW
Sbjct: 629 VILW 632
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/164 (22%), Positives = 70/164 (42%), Gaps = 3/164 (1%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKYMASAS 82
ITA +P+++ + T+S + W + G++ H V + F + +A+
Sbjct: 69 ITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGG 128
Query: 83 RDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWSTHKHKFI 140
D VR+W T F+ V V F D ++++ +++ D +++WS +
Sbjct: 129 CDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCL 188
Query: 141 SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
+ H + V S DG + S DK +W+L S + T
Sbjct: 189 AVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRT 232
Score = 53.6 bits (123), Expect = 3e-06
Identities = 35/149 (23%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Query: 155 MSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH-LAWHPSGCYVAVATSHGNV 213
+S D ++ + S W G +K + + +A+ P+ +A G V
Sbjct: 74 LSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAV 133
Query: 214 KLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL--TASKDGKMKILDLLEGHPIFTLSG 271
+++DI H ++ V VA HP + +L +++ D +++ L + + L+
Sbjct: 134 RVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTA 193
Query: 272 HNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
H V ++ FS G T S+G DK+ IW
Sbjct: 194 HYSAVTSLAFSADGHTMLSSGRDKICIIW 222
Score = 44.8 bits (101), Expect = 0.001
Identities = 57/281 (20%), Positives = 113/281 (40%), Gaps = 25/281 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR---FQGHDEAVM------ 67
L H +A+T+L ++ + + +S D ++WDL+ + F+ + AV+
Sbjct: 191 LTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPV 250
Query: 68 -DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFSSDGSKIIT 122
+ S G Y +A T+R+W +G +A Q + + ++T
Sbjct: 251 SQLGVKSPGLYFLTAGDQGTLRVW-EAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLT 309
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCAR-MSNDGSIIASCSDDKSTKLWNLDSGEC 181
A+ D + L+ + F G++ V R + + S + S+ K++ L + C
Sbjct: 310 ATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSAC 369
Query: 182 --IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAV-T 235
+H + D+ L L G A +V+++ + V S H +V T
Sbjct: 370 QILHGHTDIV---LALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGT 426
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPV 276
S+++T S+D +K+ L + + NGP+
Sbjct: 427 VCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPI 467
>BC010231-1|AAH10231.1| 808|Homo sapiens transducin (beta)-like 3
protein.
Length = 808
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/301 (24%), Positives = 133/301 (44%), Gaps = 19/301 (6%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF--SSSGKY 77
H + + ++P +AT D +V +WD+ ++ F+G V V F +
Sbjct: 108 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLL 167
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW---ST 134
+ S++ D +R+W + AH V S+ FS+DG ++++ DK+ +W S
Sbjct: 168 LFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSC 227
Query: 135 HKHKFISSFVGHTNWVRCAR-------MSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
+ + F V + + G + D + ++W SG+C++T
Sbjct: 228 QATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQ 287
Query: 188 LKGHGLHLAW----HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA-IHPS 242
G G L H +G V AT+ N+ LY+ R+ L + ++ ++E V V + P
Sbjct: 288 PPGPGQELTHCTLAHTAGV-VLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPE 346
Query: 243 GSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
S+++ AS +K+ +L + L GH V A++ G F+S D+ V IW+
Sbjct: 347 DSHVVVASNSPCLKVFEL-QTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRM 405
Query: 303 N 303
N
Sbjct: 406 N 406
Score = 87.8 bits (208), Expect = 2e-16
Identities = 70/334 (20%), Positives = 143/334 (42%), Gaps = 22/334 (6%)
Query: 13 LKKQLKGHKNAITAL-YYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
L+KQ G+ + + + P D + +S + +++L+ T GH + V+ +
Sbjct: 326 LQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQ-TSACQILHGHTDIVLALDV 384
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGST---GMFKAHSQTVRSVQFSS-DGSKIITASDDK 127
G AS ++D++VRIW G H+ +V +V S S ++T S D
Sbjct: 385 FRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDC 444
Query: 128 VVKLWSTHKHKFISSFVG---------------HTNWVRCARMSNDGSIIASCSDDKSTK 172
VKLW K + H + ++ + ++A+ S D++ K
Sbjct: 445 TVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAK 504
Query: 173 LWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE 232
LW L + + + + + + P +A A++ G +KL+ ++ + ++ + H+
Sbjct: 505 LWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDA 564
Query: 233 AVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+V +VA G+ +L++ DG +K+ + + TL H V ++ S D +
Sbjct: 565 SVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGA 624
Query: 293 DDKLVFIWKTNFTDLSSESKENEGQNMITGQRHL 326
D V +WK + T+ ++ + + Q+ L
Sbjct: 625 SDSRVILWK-DVTEAEQAEEQARQEEQVVRQQEL 657
Score = 74.9 bits (176), Expect = 1e-12
Identities = 68/287 (23%), Positives = 126/287 (43%), Gaps = 25/287 (8%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF-SSSGKYMASASRDKTVRIWVPTV 94
+ T++ D+++LL++ R +F G+ E V+DV F ++ AS ++++
Sbjct: 307 VLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVF-ELQ 365
Query: 95 TGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH---KFISSFVGHTN--- 148
T + + H+ V ++ G + + D+ V++W +K ++ GHT+
Sbjct: 366 TSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVG 425
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNL-----------DSGECI---HTYKDLKGHGLH 194
V C+R+ S + + S D + KLW L D+G + T + ++
Sbjct: 426 TVCCSRLKE--SFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDIN 483
Query: 195 -LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDG 253
+A P+ +A + KL+ + L+ +S H + V P + TAS DG
Sbjct: 484 SVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADG 543
Query: 254 KMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+K+ L + + T GH+ V V F G S+G D LV +W
Sbjct: 544 TIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLW 590
Score = 68.1 bits (159), Expect = 1e-10
Identities = 36/124 (29%), Positives = 57/124 (45%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P+ L GH+ + + ++P DQ +AT+S D ++ LW L+ F+GHD +V+
Sbjct: 509 PQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLK 568
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V F S G + S+ D V++W AH V + S +T + D
Sbjct: 569 VAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSR 628
Query: 129 VKLW 132
V LW
Sbjct: 629 VILW 632
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/164 (22%), Positives = 70/164 (42%), Gaps = 3/164 (1%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKYMASAS 82
ITA +P+++ + T+S + W + G++ H V + F + +A+
Sbjct: 69 ITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGG 128
Query: 83 RDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWSTHKHKFI 140
D VR+W T F+ V V F D ++++ +++ D +++WS +
Sbjct: 129 CDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCL 188
Query: 141 SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
+ H + V S DG + S DK +W+L S + T
Sbjct: 189 AVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRT 232
Score = 53.6 bits (123), Expect = 3e-06
Identities = 35/149 (23%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Query: 155 MSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH-LAWHPSGCYVAVATSHGNV 213
+S D ++ + S W G +K + + +A+ P+ +A G V
Sbjct: 74 LSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAV 133
Query: 214 KLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL--TASKDGKMKILDLLEGHPIFTLSG 271
+++DI H ++ V VA HP + +L +++ D +++ L + + L+
Sbjct: 134 RVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTA 193
Query: 272 HNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
H V ++ FS G T S+G DK+ IW
Sbjct: 194 HYSAVTSLAFSADGHTMLSSGRDKICIIW 222
Score = 44.8 bits (101), Expect = 0.001
Identities = 57/281 (20%), Positives = 113/281 (40%), Gaps = 25/281 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR---FQGHDEAVM------ 67
L H +A+T+L ++ + + +S D ++WDL+ + F+ + AV+
Sbjct: 191 LTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPV 250
Query: 68 -DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFSSDGSKIIT 122
+ S G Y +A T+R+W +G +A Q + + ++T
Sbjct: 251 SQLGVKSPGLYFLTAGDQGTLRVW-EAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLT 309
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCAR-MSNDGSIIASCSDDKSTKLWNLDSGEC 181
A+ D + L+ + F G++ V R + + S + S+ K++ L + C
Sbjct: 310 ATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSAC 369
Query: 182 --IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAV-T 235
+H + D+ L L G A +V+++ + V S H +V T
Sbjct: 370 QILHGHTDIV---LALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGT 426
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPV 276
S+++T S+D +K+ L + + NGP+
Sbjct: 427 VCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPI 467
>AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4
protein.
Length = 707
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 413 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 469
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR VQ+ DG ++++ + D +VK+
Sbjct: 470 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKV 525
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 526 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 580
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 581 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 638
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 639 TSSDDGTVKLWDLKTGEFIRNL 660
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 13/206 (6%)
Query: 97 STGMFKAHSQ-TVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
S + K H + +QF G++I++ SDD +K+WS K + + VGHT V ++M
Sbjct: 372 SPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM 429
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVK 214
+ +II S S D++ K+WN ++GECIHT L GH + H V + ++
Sbjct: 430 RD--NIIISGSTDRTLKVWNAETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLR 484
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
++DI T + H AV + G +++ + D +K+ D + TL GH
Sbjct: 485 VWDIETGQCLHVLMGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN 542
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ F G S D + +W
Sbjct: 543 RVYSLQFD--GIHVVSGSLDTSIRVW 566
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 497 LMGHVAAVRCVQYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 552
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 553 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 610
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 611 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 667
>AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7
protein.
Length = 627
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 333 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 389
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR VQ+ DG ++++ + D +VK+
Sbjct: 390 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKV 445
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 446 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 500
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 501 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 558
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 559 TSSDDGTVKLWDLKTGEFIRNL 580
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 13/206 (6%)
Query: 97 STGMFKAHSQ-TVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
S + K H + +QF G++I++ SDD +K+WS K + + VGHT V ++M
Sbjct: 292 SPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM 349
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVK 214
+ +II S S D++ K+WN ++GECIHT L GH + H V + ++
Sbjct: 350 RD--NIIISGSTDRTLKVWNAETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLR 404
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
++DI T + H AV + G +++ + D +K+ D + TL GH
Sbjct: 405 VWDIETGQCLHVLMGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN 462
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ F G S D + +W
Sbjct: 463 RVYSLQFD--GIHVVSGSLDTSIRVW 486
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 417 LMGHVAAVRCVQYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 472
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 473 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 530
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 531 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 587
>AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10
protein.
Length = 589
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 295 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 351
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR VQ+ DG ++++ + D +VK+
Sbjct: 352 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKV 407
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 408 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 462
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 463 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 520
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 521 TSSDDGTVKLWDLKTGEFIRNL 542
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 13/206 (6%)
Query: 97 STGMFKAHSQ-TVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
S + K H + +QF G++I++ SDD +K+WS K + + VGHT V ++M
Sbjct: 254 SPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM 311
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVK 214
+ +II S S D++ K+WN ++GECIHT L GH + H V + ++
Sbjct: 312 RD--NIIISGSTDRTLKVWNAETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLR 366
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
++DI T + H AV + G +++ + D +K+ D + TL GH
Sbjct: 367 VWDIETGQCLHVLMGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN 424
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ F G S D + +W
Sbjct: 425 RVYSLQFD--GIHVVSGSLDTSIRVW 448
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 379 LMGHVAAVRCVQYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 434
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 435 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 492
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 493 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 549
>AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 627
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 333 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 389
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR VQ+ DG ++++ + D +VK+
Sbjct: 390 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKV 445
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 446 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 500
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 501 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 558
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 559 TSSDDGTVKLWDLKTGEFIRNL 580
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 13/206 (6%)
Query: 97 STGMFKAHSQ-TVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
S + K H + +QF G++I++ SDD +K+WS K + + VGHT V ++M
Sbjct: 292 SPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM 349
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVK 214
+ +II S S D++ K+WN ++GECIHT L GH + H V + ++
Sbjct: 350 RD--NIIISGSTDRTLKVWNAETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLR 404
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
++DI T + H AV + G +++ + D +K+ D + TL GH
Sbjct: 405 VWDIETGQCLHVLMGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN 462
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ F G S D + +W
Sbjct: 463 RVYSLQFD--GIHVVSGSLDTSIRVW 486
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 417 LMGHVAAVRCVQYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 472
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 473 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 530
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 531 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 587
>AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ11071 fis, clone PLACE1004937, moderately
similar to SEL-10 PROTEIN. ).
Length = 553
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 259 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 315
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR VQ+ DG ++++ + D +VK+
Sbjct: 316 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKV 371
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 372 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 426
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 427 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 484
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 485 TSSDDGTVKLWDLKTGEFIRNL 506
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 13/206 (6%)
Query: 97 STGMFKAHSQ-TVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
S + K H + +QF G++I++ SDD +K+WS K + + VGHT V ++M
Sbjct: 218 SPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM 275
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVK 214
+ +II S S D++ K+WN ++GECIHT L GH + H V + ++
Sbjct: 276 RD--NIIISGSTDRTLKVWNAETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLR 330
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
++DI T + H AV + G +++ + D +K+ D + TL GH
Sbjct: 331 VWDIETGQCLHVLMGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN 388
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ F G S D + +W
Sbjct: 389 RVYSLQFD--GIHVVSGSLDTSIRVW 412
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 343 LMGHVAAVRCVQYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 398
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 399 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 456
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 457 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 513
>AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form
protein.
Length = 627
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 333 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 389
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR VQ+ DG ++++ + D +VK+
Sbjct: 390 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKV 445
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 446 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 500
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 501 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 558
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 559 TSSDDGTVKLWDLKTGEFIRNL 580
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 13/206 (6%)
Query: 97 STGMFKAHSQ-TVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
S + K H + +QF G++I++ SDD +K+WS K + + VGHT V ++M
Sbjct: 292 SPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM 349
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVK 214
+ +II S S D++ K+WN ++GECIHT L GH + H V + ++
Sbjct: 350 RD--NIIISGSTDRTLKVWNAETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLR 404
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
++DI T + H AV + G +++ + D +K+ D + TL GH
Sbjct: 405 VWDIETGQCLHVLMGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN 462
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ F G S D + +W
Sbjct: 463 RVYSLQFD--GIHVVSGSLDTSIRVW 486
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 417 LMGHVAAVRCVQYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 472
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 473 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 530
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 531 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 587
>AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form
protein.
Length = 707
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 413 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 469
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR VQ+ DG ++++ + D +VK+
Sbjct: 470 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKV 525
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 526 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 580
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 581 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 638
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 639 TSSDDGTVKLWDLKTGEFIRNL 660
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 13/206 (6%)
Query: 97 STGMFKAHSQ-TVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
S + K H + +QF G++I++ SDD +K+WS K + + VGHT V ++M
Sbjct: 372 SPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM 429
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVK 214
+ +II S S D++ K+WN ++GECIHT L GH + H V + ++
Sbjct: 430 RD--NIIISGSTDRTLKVWNAETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLR 484
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
++DI T + H AV + G +++ + D +K+ D + TL GH
Sbjct: 485 VWDIETGQCLHVLMGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN 542
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ F G S D + +W
Sbjct: 543 RVYSLQFD--GIHVVSGSLDTSIRVW 566
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 497 LMGHVAAVRCVQYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 552
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 553 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 610
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 611 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 667
>AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30
protein.
Length = 561
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 267 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 323
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR VQ+ DG ++++ + D +VK+
Sbjct: 324 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKV 379
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 380 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 434
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 435 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 492
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 493 TSSDDGTVKLWDLKTGEFIRNL 514
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 13/206 (6%)
Query: 97 STGMFKAHSQ-TVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
S + K H + +QF G++I++ SDD +K+WS K + + VGHT V ++M
Sbjct: 226 SPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM 283
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVK 214
+ +II S S D++ K+WN ++GECIHT L GH + H V + ++
Sbjct: 284 RD--NIIISGSTDRTLKVWNAETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLR 338
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
++DI T + H AV + G +++ + D +K+ D + TL GH
Sbjct: 339 VWDIETGQCLHVLMGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN 396
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ F G S D + +W
Sbjct: 397 RVYSLQFD--GIHVVSGSLDTSIRVW 420
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 351 LMGHVAAVRCVQYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 406
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 407 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 464
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 465 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 521
>AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 624
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 330 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 386
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR VQ+ DG ++++ + D +VK+
Sbjct: 387 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKV 442
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 443 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 497
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 498 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 555
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 556 TSSDDGTVKLWDLKTGEFIRNL 577
Score = 79.8 bits (188), Expect = 4e-14
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 13/206 (6%)
Query: 97 STGMFKAHSQ-TVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARM 155
S + K H + +QF G++I++ SDD +K+WS K + + VGHT V ++M
Sbjct: 289 SPKVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM 346
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVK 214
+ +II S S D++ K+WN ++GECIHT L GH + H V + ++
Sbjct: 347 RD--NIIISGSTDRTLKVWNAETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLR 401
Query: 215 LYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNG 274
++DI T + H AV + G +++ + D +K+ D + TL GH
Sbjct: 402 VWDIETGQCLHVLMGHVAAVR--CVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTN 459
Query: 275 PVNAVNFSPTGDTFSSAGDDKLVFIW 300
V ++ F G S D + +W
Sbjct: 460 RVYSLQFD--GIHVVSGSLDTSIRVW 483
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 414 LMGHVAAVRCVQYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 469
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 470 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 527
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 528 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 584
>AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3
variant protein.
Length = 832
Score = 96.7 bits (230), Expect = 3e-19
Identities = 73/301 (24%), Positives = 133/301 (44%), Gaps = 19/301 (6%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF--SSSGKY 77
H + + ++P +AT D +V +WD+ ++ F+G V V F +
Sbjct: 132 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLL 191
Query: 78 MASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW---ST 134
+ S++ D +R+W + AH V S+ FS+DG ++++ DK+ +W S
Sbjct: 192 LFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSC 251
Query: 135 HKHKFISSFVGHTNWVRCAR-------MSNDGSIIASCSDDKSTKLWNLDSGECIHTYKD 187
+ + F V + + G + D + ++W SG+C++T
Sbjct: 252 QATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQ 311
Query: 188 LKGHGLHLAW----HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA-IHPS 242
G G L H +G V AT+ N+ LY+ R+ L + ++ ++E V V + P
Sbjct: 312 PPGPGRELTHCTLAHTAGV-VLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPE 370
Query: 243 GSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKT 302
S+++ AS +K+ +L + L GH V A++ G F+S D+ V IW+
Sbjct: 371 DSHVVVASNSPCLKVFEL-QTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRM 429
Query: 303 N 303
N
Sbjct: 430 N 430
Score = 87.4 bits (207), Expect = 2e-16
Identities = 70/334 (20%), Positives = 143/334 (42%), Gaps = 22/334 (6%)
Query: 13 LKKQLKGHKNAITAL-YYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
L+KQ G+ + + + P D + +S + +++L+ T GH + V+ +
Sbjct: 350 LQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQ-TSACQILHGHTDIVLALDV 408
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGST---GMFKAHSQTVRSVQFSS-DGSKIITASDDK 127
G AS ++D++VRIW G H+ +V +V S S ++T S D
Sbjct: 409 FRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDC 468
Query: 128 VVKLWSTHKHKFISSFVG---------------HTNWVRCARMSNDGSIIASCSDDKSTK 172
VKLW K + H + ++ + ++A+ S D++ K
Sbjct: 469 TVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAK 528
Query: 173 LWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE 232
LW L + + + + + + P +A A++ G +KL+ ++ + ++ + H+
Sbjct: 529 LWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDA 588
Query: 233 AVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+V +VA G+ +L++ DG +K+ + + TL H V ++ S D +
Sbjct: 589 SVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGA 648
Query: 293 DDKLVFIWKTNFTDLSSESKENEGQNMITGQRHL 326
D V +WK + T+ ++ + + Q+ L
Sbjct: 649 SDSRVILWK-DVTEAEQAEEQARQEEQVVRQQEL 681
Score = 74.9 bits (176), Expect = 1e-12
Identities = 68/287 (23%), Positives = 126/287 (43%), Gaps = 25/287 (8%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF-SSSGKYMASASRDKTVRIWVPTV 94
+ T++ D+++LL++ R +F G+ E V+DV F ++ AS ++++
Sbjct: 331 VLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVF-ELQ 389
Query: 95 TGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH---KFISSFVGHTN--- 148
T + + H+ V ++ G + + D+ V++W +K ++ GHT+
Sbjct: 390 TSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVG 449
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNL-----------DSGECI---HTYKDLKGHGLH 194
V C+R+ S + + S D + KLW L D+G + T + ++
Sbjct: 450 TVCCSRLKE--SFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDKDIN 507
Query: 195 -LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDG 253
+A P+ +A + KL+ + L+ +S H + V P + TAS DG
Sbjct: 508 SVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADG 567
Query: 254 KMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+K+ L + + T GH+ V V F G S+G D LV +W
Sbjct: 568 TIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLW 614
Score = 68.1 bits (159), Expect = 1e-10
Identities = 36/124 (29%), Positives = 57/124 (45%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P+ L GH+ + + ++P DQ +AT+S D ++ LW L+ F+GHD +V+
Sbjct: 533 PQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLK 592
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V F S G + S+ D V++W AH V + S +T + D
Sbjct: 593 VAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSR 652
Query: 129 VKLW 132
V LW
Sbjct: 653 VILW 656
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/164 (22%), Positives = 70/164 (42%), Gaps = 3/164 (1%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRSYRFQGHDEAVMDVTFSSSGKYMASAS 82
ITA +P+++ + T+S + W + G++ H V + F + +A+
Sbjct: 93 ITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGG 152
Query: 83 RDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII--TASDDKVVKLWSTHKHKFI 140
D VR+W T F+ V V F D ++++ +++ D +++WS +
Sbjct: 153 CDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCL 212
Query: 141 SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHT 184
+ H + V S DG + S DK +W+L S + T
Sbjct: 213 AVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRT 256
Score = 53.6 bits (123), Expect = 3e-06
Identities = 35/149 (23%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Query: 155 MSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH-LAWHPSGCYVAVATSHGNV 213
+S D ++ + S W G +K + + +A+ P+ +A G V
Sbjct: 98 LSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAV 157
Query: 214 KLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL--TASKDGKMKILDLLEGHPIFTLSG 271
+++DI H ++ V VA HP + +L +++ D +++ L + + L+
Sbjct: 158 RVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTA 217
Query: 272 HNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
H V ++ FS G T S+G DK+ IW
Sbjct: 218 HYSAVTSLAFSADGHTMLSSGRDKICIIW 246
Score = 42.7 bits (96), Expect = 0.006
Identities = 56/281 (19%), Positives = 113/281 (40%), Gaps = 25/281 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR---FQGHDEAVM------ 67
L H +A+T+L ++ + + +S D ++WDL+ + F+ + AV+
Sbjct: 215 LTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPV 274
Query: 68 -DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFSSDGSKIIT 122
+ S G Y +A T+R+W +G +A + + + ++T
Sbjct: 275 SQLGVKSPGLYFLTAGDQGTLRVW-EAASGQCVYTQAQPPGPGRELTHCTLAHTAGVVLT 333
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCAR-MSNDGSIIASCSDDKSTKLWNLDSGEC 181
A+ D + L+ + F G++ V R + + S + S+ K++ L + C
Sbjct: 334 ATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSAC 393
Query: 182 --IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAV-T 235
+H + D+ L L G A +V+++ + V S H +V T
Sbjct: 394 QILHGHTDIV---LALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGT 450
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPV 276
S+++T S+D +K+ L + + NGP+
Sbjct: 451 VCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPI 491
>CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein.
Length = 305
Score = 96.3 bits (229), Expect = 5e-19
Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 12/297 (4%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQ----IATSSLDNSVLLWDLRGTM--RSYRFQGHDEAV 66
L KQ + H +AI ++ + N ++ + T SLD+ V +W R + +GH V
Sbjct: 8 LFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGV 67
Query: 67 MDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
+ V S + AS+S D +R+W A ++ FS D + T +
Sbjct: 68 VSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHV 127
Query: 127 KVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
V ++ K S ++ S DG +AS + D ++++ +G+ +HT
Sbjct: 128 GKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT-- 185
Query: 187 DLKGHGL---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSG 243
L+GH + L + P + A+ G +K+YD++ NL H V VA P
Sbjct: 186 -LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLGGHASWVLNVAFCPDD 244
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
++ +++S D +K+ D+ + T H V V ++ G S GDD+ + I+
Sbjct: 245 THFVSSSSDKNVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 96.3 bits (229), Expect = 5e-19
Identities = 45/191 (23%), Positives = 90/191 (47%)
Query: 27 LYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKT 86
L ++P+ Q +AT + V ++ + + Y + ++ + +S GKY+AS + D
Sbjct: 112 LAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGI 171
Query: 87 VRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGH 146
+ I+ + H+ +RS+ FS D ++TASDD +K++ + GH
Sbjct: 172 INIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLGGH 231
Query: 147 TNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAV 206
+WV D + S S DK+ K+W++ + C+HT+ D + + ++ +G +
Sbjct: 232 ASWVLNVAFCPDDTHFVSSSSDKNVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVS 291
Query: 207 ATSHGNVKLYD 217
+ +YD
Sbjct: 292 VGDDQEIHIYD 302
Score = 88.2 bits (209), Expect = 1e-16
Identities = 55/213 (25%), Positives = 97/213 (45%), Gaps = 6/213 (2%)
Query: 102 KAHSQTVRSVQFSSDGSK----IITASDDKVVKLWSTHKHKFIS--SFVGHTNWVRCARM 155
+AH + SV + ++ + ++T S D +VK+W + S GH V +
Sbjct: 13 QAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDI 72
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKL 215
S+ I AS S D +LW+L++G+ I + LA+ P Y+A T G V +
Sbjct: 73 SHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNI 132
Query: 216 YDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGP 275
+ + + + + +A P G Y+ + + DG + I D+ G + TL GH P
Sbjct: 133 FGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMP 192
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLS 308
+ ++ FSP +A DD + I+ +L+
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDVQHANLA 225
Score = 85.4 bits (202), Expect = 9e-16
Identities = 54/247 (21%), Positives = 108/247 (43%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L+ L+GH+ + ++ + A+SSLD + LWDL + + FS
Sbjct: 56 LQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFS 115
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+Y+A+ + V I+ + + S+ +S DG + + + D ++ ++
Sbjct: 116 PDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + + GH +R S D ++ + SDD K++++ T
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLGGHASWV 235
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
L++A+ P + ++S NVK++D+ T V + H + V V + +GS I++ D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKNVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 253 GKMKILD 259
++ I D
Sbjct: 296 QEIHIYD 302
>BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein.
Length = 621
Score = 95.1 bits (226), Expect = 1e-18
Identities = 72/262 (27%), Positives = 121/262 (46%), Gaps = 18/262 (6%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CL+ L GH + + D I + S D ++ +W+ + GH V +
Sbjct: 327 CLRT-LVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHL 383
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
K + S SRD T+R+W + H VR V++ DG ++++ + D +VK+
Sbjct: 384 HE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVRY--DGRRVVSGAYDFMVKV 439
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGH 191
W + + GHTN R + DG + S S D S ++W++++G CIHT L GH
Sbjct: 440 WDPETETCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHT---LTGH 494
Query: 192 -GLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAVTQVAIHPSGSYIL 247
L + + VK++DI+T +Q + H AVT + + ++++
Sbjct: 495 QSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVT--CLQFNKNFVI 552
Query: 248 TASKDGKMKILDLLEGHPIFTL 269
T+S DG +K+ DL G I L
Sbjct: 553 TSSDDGTVKLWDLKTGEFIRNL 574
Score = 78.6 bits (185), Expect = 1e-13
Identities = 54/185 (29%), Positives = 90/185 (48%), Gaps = 10/185 (5%)
Query: 117 GSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNL 176
G++I++ SDD +K+WS K + + VGHT V ++M + +II S S D++ K+WN
Sbjct: 305 GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRD--NIIISGSTDRTLKVWNA 362
Query: 177 DSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
++GECIHT L GH + H V + ++++DI T + H AV
Sbjct: 363 ETGECIHT---LYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVR 419
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ G +++ + D +K+ D + TL GH V ++ F G S D
Sbjct: 420 --CVRYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GIHVVSGSLDT 475
Query: 296 LVFIW 300
+ +W
Sbjct: 476 SIRVW 480
Score = 63.7 bits (148), Expect = 3e-09
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 11/179 (6%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH A+ + Y+ +++ + + D V +WD + QGH V + F G
Sbjct: 411 LMGHVAAVRCVRYD--GRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFD--GI 466
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHK 136
++ S S D ++R+W H ++ + +++ + D VK+W
Sbjct: 467 HVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDN--ILVSGNADSTVKIWDIKT 524
Query: 137 HKFISSFVG---HTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + + G H + V C + N +I S SDD + KLW+L +GE I L+ G
Sbjct: 525 GQCLQTLQGPNKHQSAVTCLQF-NKNFVITS-SDDGTVKLWDLKTGEFIRNLVTLESGG 581
>BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1
(PRL1 homolog, Arabidopsis) protein.
Length = 514
Score = 94.7 bits (225), Expect = 1e-18
Identities = 63/232 (27%), Positives = 96/232 (41%), Gaps = 4/232 (1%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDG 159
+ H VR + +T S D+ +K+W K S GH + VR +S
Sbjct: 199 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 258
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+ SC +DK K W+L+ + I Y L HP+ + + +++D+R
Sbjct: 259 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 318
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
T V S H AV V + I+T S D +++ DL+ G TL+ H V AV
Sbjct: 319 TKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAV 378
Query: 280 NFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGI 331
P TF+S D + WK F D S + G N I + +G+
Sbjct: 379 VLHPRHYTFASGSPDN-IKQWK--FPD-GSFIQNLSGHNAIINTLTVNSDGV 426
Score = 93.1 bits (221), Expect = 4e-18
Identities = 58/252 (23%), Positives = 101/252 (40%), Gaps = 2/252 (0%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L + + GH + + P +Q T S D ++ +WDL GH V V S
Sbjct: 196 LYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS 255
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+ Y+ S DK V+ W + H V + ++T S D ++W
Sbjct: 256 TRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 315
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + GHTN V R I + S D + +LW+L +G+ T + K
Sbjct: 316 DVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSV 375
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
+ HP Y + S N+K + + +Q S HN + + ++ G +++ + +
Sbjct: 376 RAVVLHPRH-YTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDG-VLVSGADN 433
Query: 253 GKMKILDLLEGH 264
G M + D G+
Sbjct: 434 GTMHLWDWRTGY 445
Score = 83.4 bits (197), Expect = 3e-15
Identities = 63/256 (24%), Positives = 112/256 (43%), Gaps = 15/256 (5%)
Query: 57 YR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGM-FKAHSQTVRSVQFS 114
YR GH V + ++ + S D+T++IW +G + H TVR V S
Sbjct: 197 YRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIW-DLASGKLKLSLTGHISTVRGVIVS 255
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
+ + + +DK VK W +K I + GH + V + ++ +CS D + ++W
Sbjct: 256 TRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 315
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVA----VATSHGN-VKLYDIRTHNLVQYYSI 229
++ + +HT L GH +A C A + SH ++L+D+ +
Sbjct: 316 DVRTKASVHT---LSGHTNAVA--TVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTN 370
Query: 230 HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFS 289
H ++V V +HP Y + +K +G I LSGHN +N + + G S
Sbjct: 371 HKKSVRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVS 429
Query: 290 SAGDDKL-VFIWKTNF 304
A + + ++ W+T +
Sbjct: 430 GADNGTMHLWDWRTGY 445
Score = 79.0 bits (186), Expect = 7e-14
Identities = 69/256 (26%), Positives = 104/256 (40%), Gaps = 16/256 (6%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
LK L GH + + + + + + D V WDL + GH AV +
Sbjct: 238 LKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLH 297
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+ + + SRD T RIW S H+ V +V+ + +IIT S D ++LW
Sbjct: 298 PTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLW 357
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + H VR + AS S D + K W G I ++L GH
Sbjct: 358 DLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFI---QNLSGHN 413
Query: 193 L---HLAWHPSGCYVAVATSHGNVKLYDIRT-------HNLVQYYSIHNEA-VTQVAIHP 241
L + G V+ A +G + L+D RT H VQ S+ +E+ + A
Sbjct: 414 AIINTLTVNSDGVLVSGA-DNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQ 472
Query: 242 SGSYILTASKDGKMKI 257
S S +LTA D +K+
Sbjct: 473 SESRLLTAEADKTIKV 488
Score = 44.0 bits (99), Expect = 0.003
Identities = 26/82 (31%), Positives = 36/82 (43%)
Query: 223 LVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFS 282
L + S H V +A+ P + +T S D +KI DL G +L+GH V V S
Sbjct: 196 LYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS 255
Query: 283 PTGDTFSSAGDDKLVFIWKTNF 304
S G+DK V W +
Sbjct: 256 TRSPYLFSCGEDKQVKCWDLEY 277
Score = 35.1 bits (77), Expect = 1.2
Identities = 27/124 (21%), Positives = 53/124 (42%), Gaps = 10/124 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L HK ++ A+ +P A+ S DN + W GH+ + +T +S G
Sbjct: 368 LTNHKKSVRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSGHNAIINTLTVNSDG- 425
Query: 77 YMASASRDKTVRIW-------VPTVTGSTGMFKAHSQT-VRSVQFSSDGSKIITASDDKV 128
+ S + + T+ +W V + S++ + + F S+++TA DK
Sbjct: 426 VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKT 485
Query: 129 VKLW 132
+K++
Sbjct: 486 IKVY 489
>BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein.
Length = 505
Score = 94.7 bits (225), Expect = 1e-18
Identities = 63/232 (27%), Positives = 96/232 (41%), Gaps = 4/232 (1%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDG 159
+ H VR + +T S D+ +K+W K S GH + VR +S
Sbjct: 190 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 249
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+ SC +DK K W+L+ + I Y L HP+ + + +++D+R
Sbjct: 250 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 309
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
T V S H AV V + I+T S D +++ DL+ G TL+ H V AV
Sbjct: 310 TKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAV 369
Query: 280 NFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGI 331
P TF+S D + WK F D S + G N I + +G+
Sbjct: 370 VLHPRHYTFASGSPDN-IKQWK--FPD-GSFIQNLSGHNAIINTLTVNSDGV 417
Score = 93.1 bits (221), Expect = 4e-18
Identities = 58/252 (23%), Positives = 101/252 (40%), Gaps = 2/252 (0%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L + + GH + + P +Q T S D ++ +WDL GH V V S
Sbjct: 187 LYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS 246
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+ Y+ S DK V+ W + H V + ++T S D ++W
Sbjct: 247 TRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 306
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + GHTN V R I + S D + +LW+L +G+ T + K
Sbjct: 307 DVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSV 366
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
+ HP Y + S N+K + + +Q S HN + + ++ G +++ + +
Sbjct: 367 RAVVLHPRH-YTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDG-VLVSGADN 424
Query: 253 GKMKILDLLEGH 264
G M + D G+
Sbjct: 425 GTMHLWDWRTGY 436
Score = 83.4 bits (197), Expect = 3e-15
Identities = 63/256 (24%), Positives = 112/256 (43%), Gaps = 15/256 (5%)
Query: 57 YR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGM-FKAHSQTVRSVQFS 114
YR GH V + ++ + S D+T++IW +G + H TVR V S
Sbjct: 188 YRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIW-DLASGKLKLSLTGHISTVRGVIVS 246
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
+ + + +DK VK W +K I + GH + V + ++ +CS D + ++W
Sbjct: 247 TRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 306
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVA----VATSHGN-VKLYDIRTHNLVQYYSI 229
++ + +HT L GH +A C A + SH ++L+D+ +
Sbjct: 307 DVRTKASVHT---LSGHTNAVA--TVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTN 361
Query: 230 HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFS 289
H ++V V +HP Y + +K +G I LSGHN +N + + G S
Sbjct: 362 HKKSVRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVS 420
Query: 290 SAGDDKL-VFIWKTNF 304
A + + ++ W+T +
Sbjct: 421 GADNGTMHLWDWRTGY 436
Score = 79.0 bits (186), Expect = 7e-14
Identities = 69/256 (26%), Positives = 104/256 (40%), Gaps = 16/256 (6%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
LK L GH + + + + + + D V WDL + GH AV +
Sbjct: 229 LKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLH 288
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+ + + SRD T RIW S H+ V +V+ + +IIT S D ++LW
Sbjct: 289 PTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLW 348
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + H VR + AS S D + K W G I ++L GH
Sbjct: 349 DLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFI---QNLSGHN 404
Query: 193 L---HLAWHPSGCYVAVATSHGNVKLYDIRT-------HNLVQYYSIHNEA-VTQVAIHP 241
L + G V+ A +G + L+D RT H VQ S+ +E+ + A
Sbjct: 405 AIINTLTVNSDGVLVSGA-DNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQ 463
Query: 242 SGSYILTASKDGKMKI 257
S S +LTA D +K+
Sbjct: 464 SESRLLTAEADKTIKV 479
Score = 44.0 bits (99), Expect = 0.003
Identities = 26/82 (31%), Positives = 36/82 (43%)
Query: 223 LVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFS 282
L + S H V +A+ P + +T S D +KI DL G +L+GH V V S
Sbjct: 187 LYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS 246
Query: 283 PTGDTFSSAGDDKLVFIWKTNF 304
S G+DK V W +
Sbjct: 247 TRSPYLFSCGEDKQVKCWDLEY 268
Score = 35.1 bits (77), Expect = 1.2
Identities = 27/124 (21%), Positives = 53/124 (42%), Gaps = 10/124 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L HK ++ A+ +P A+ S DN + W GH+ + +T +S G
Sbjct: 359 LTNHKKSVRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSGHNAIINTLTVNSDG- 416
Query: 77 YMASASRDKTVRIW-------VPTVTGSTGMFKAHSQT-VRSVQFSSDGSKIITASDDKV 128
+ S + + T+ +W V + S++ + + F S+++TA DK
Sbjct: 417 VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKT 476
Query: 129 VKLW 132
+K++
Sbjct: 477 IKVY 480
>AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing
gene 21 protein.
Length = 271
Score = 94.7 bits (225), Expect = 1e-18
Identities = 63/203 (31%), Positives = 106/203 (52%), Gaps = 12/203 (5%)
Query: 58 RFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPT-VTGSTGMFKAHSQTVRSVQFSSD 116
RF GH + V+ V FSS + + S SRDKT+++W V T ++HS+ V V+FS +
Sbjct: 54 RFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPN 113
Query: 117 GSK--IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
S I++ DK+VK+W+ K ++ +GHT ++ +S DGS+ AS D LW
Sbjct: 114 SSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLW 173
Query: 175 NLDSGECIHTYKDLKGHGL--HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE 232
+L+ G+ ++T L G + L + P+ ++ AT ++K++D+ +V + E
Sbjct: 174 DLNEGKHLYT---LDGGDIINALCFSPNRYWLCAATG-PSIKIWDLEGKIIVD--ELKQE 227
Query: 233 AV-TQVAIHPSGSYILTASKDGK 254
+ T P L S DG+
Sbjct: 228 VISTSSKAEPPQCTSLAWSADGQ 250
Score = 80.2 bits (189), Expect = 3e-14
Identities = 63/217 (29%), Positives = 94/217 (43%), Gaps = 14/217 (6%)
Query: 97 STGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWST-HKHKFISSFVGHTNWVRCARM 155
+T F H++ V SV FSSD +I++ S DK +KLW+T K+ H+ WV C R
Sbjct: 51 TTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRF 110
Query: 156 SNDGS--IIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNV 213
S + S II SC DK K+WNL + + + G+ + P G A G
Sbjct: 111 SPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQA 170
Query: 214 KLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL--------LEGHP 265
L+D+ Y++ + Y L A+ +KI DL L+
Sbjct: 171 MLWDLNEGK--HLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEV 228
Query: 266 IFTLSGHNGP-VNAVNFSPTGDTFSSAGDDKLVFIWK 301
I T S P ++ +S G T + D LV +W+
Sbjct: 229 ISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQ 265
Score = 52.8 bits (121), Expect = 6e-06
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 3/134 (2%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMR-SYRFQGHDEAVMDVTFS- 72
++ GH + ++ ++ +++QI + S D ++ LW+ G + + + + H E V V FS
Sbjct: 53 RRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSP 112
Query: 73 -SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
SS + S DK V++W H+ + +V S DGS + D L
Sbjct: 113 NSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAML 172
Query: 132 WSTHKHKFISSFVG 145
W ++ K + + G
Sbjct: 173 WDLNEGKHLYTLDG 186
Score = 41.1 bits (92), Expect = 0.018
Identities = 30/130 (23%), Positives = 52/130 (40%), Gaps = 13/130 (10%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
LK GH + + +P+ A+ D +LWDL Y G D +++
Sbjct: 138 LKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD--IINALCF 195
Query: 73 SSGKYMASASRDKTVRIW----------VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIIT 122
S +Y A+ +++IW + ST KA S+ +S+DG +
Sbjct: 196 SPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSS-KAEPPQCTSLAWSADGQTLFA 254
Query: 123 ASDDKVVKLW 132
D +V++W
Sbjct: 255 GYTDNLVRVW 264
Score = 36.7 bits (81), Expect = 0.39
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 230 HNEAVTQVAIHPSGS--YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDT 287
H+E V+ V P+ S I++ D +K+ +L GH G +N V SP G
Sbjct: 101 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSL 160
Query: 288 FSSAGDDKLVFIWKTN 303
+S G D +W N
Sbjct: 161 CASGGKDGQAMLWDLN 176
>AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1
protein.
Length = 514
Score = 94.7 bits (225), Expect = 1e-18
Identities = 63/232 (27%), Positives = 96/232 (41%), Gaps = 4/232 (1%)
Query: 100 MFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDG 159
+ H VR + +T S D+ +K+W K S GH + VR +S
Sbjct: 199 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 258
Query: 160 SIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
+ SC +DK K W+L+ + I Y L HP+ + + +++D+R
Sbjct: 259 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR 318
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAV 279
T V S H AV V + I+T S D +++ DL+ G TL+ H V AV
Sbjct: 319 TKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAV 378
Query: 280 NFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGI 331
P TF+S D + WK F D S + G N I + +G+
Sbjct: 379 VLHPRHYTFASGSPDN-IKQWK--FPD-GSFIQNLSGHNAIINTLTVNSDGV 426
Score = 93.1 bits (221), Expect = 4e-18
Identities = 58/252 (23%), Positives = 101/252 (40%), Gaps = 2/252 (0%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L + + GH + + P +Q T S D ++ +WDL GH V V S
Sbjct: 196 LYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS 255
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+ Y+ S DK V+ W + H V + ++T S D ++W
Sbjct: 256 TRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 315
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ + GHTN V R I + S D + +LW+L +G+ T + K
Sbjct: 316 DVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSV 375
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
+ HP Y + S N+K + + +Q S HN + + ++ G +++ + +
Sbjct: 376 RAVVLHPRH-YTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDG-VLVSGADN 433
Query: 253 GKMKILDLLEGH 264
G M + D G+
Sbjct: 434 GTMHLWDWRTGY 445
Score = 83.4 bits (197), Expect = 3e-15
Identities = 63/256 (24%), Positives = 112/256 (43%), Gaps = 15/256 (5%)
Query: 57 YR-FQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGM-FKAHSQTVRSVQFS 114
YR GH V + ++ + S D+T++IW +G + H TVR V S
Sbjct: 197 YRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIW-DLASGKLKLSLTGHISTVRGVIVS 255
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
+ + + +DK VK W +K I + GH + V + ++ +CS D + ++W
Sbjct: 256 TRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIW 315
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVA----VATSHGN-VKLYDIRTHNLVQYYSI 229
++ + +HT L GH +A C A + SH ++L+D+ +
Sbjct: 316 DVRTKASVHT---LSGHTNAVA--TVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTN 370
Query: 230 HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFS 289
H ++V V +HP Y + +K +G I LSGHN +N + + G S
Sbjct: 371 HKKSVRAVVLHPR-HYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVS 429
Query: 290 SAGDDKL-VFIWKTNF 304
A + + ++ W+T +
Sbjct: 430 GADNGTMHLWDWRTGY 445
Score = 79.0 bits (186), Expect = 7e-14
Identities = 69/256 (26%), Positives = 104/256 (40%), Gaps = 16/256 (6%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
LK L GH + + + + + + D V WDL + GH AV +
Sbjct: 238 LKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLH 297
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+ + + SRD T RIW S H+ V +V+ + +IIT S D ++LW
Sbjct: 298 PTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLW 357
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
K + H VR + AS S D + K W G I ++L GH
Sbjct: 358 DLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFI---QNLSGHN 413
Query: 193 L---HLAWHPSGCYVAVATSHGNVKLYDIRT-------HNLVQYYSIHNEA-VTQVAIHP 241
L + G V+ A +G + L+D RT H VQ S+ +E+ + A
Sbjct: 414 AIINTLTVNSDGVLVSGA-DNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQ 472
Query: 242 SGSYILTASKDGKMKI 257
S S +LTA D +K+
Sbjct: 473 SESRLLTAEADKTIKV 488
Score = 44.0 bits (99), Expect = 0.003
Identities = 26/82 (31%), Positives = 36/82 (43%)
Query: 223 LVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFS 282
L + S H V +A+ P + +T S D +KI DL G +L+GH V V S
Sbjct: 196 LYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVS 255
Query: 283 PTGDTFSSAGDDKLVFIWKTNF 304
S G+DK V W +
Sbjct: 256 TRSPYLFSCGEDKQVKCWDLEY 277
Score = 35.1 bits (77), Expect = 1.2
Identities = 27/124 (21%), Positives = 53/124 (42%), Gaps = 10/124 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L HK ++ A+ +P A+ S DN + W GH+ + +T +S G
Sbjct: 368 LTNHKKSVRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSGHNAIINTLTVNSDG- 425
Query: 77 YMASASRDKTVRIW-------VPTVTGSTGMFKAHSQT-VRSVQFSSDGSKIITASDDKV 128
+ S + + T+ +W V + S++ + + F S+++TA DK
Sbjct: 426 VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTAEADKT 485
Query: 129 VKLW 132
+K++
Sbjct: 486 IKVY 489
>U02609-1|AAA18945.1| 519|Homo sapiens transducin-like protein
protein.
Length = 519
Score = 93.9 bits (223), Expect = 2e-18
Identities = 72/292 (24%), Positives = 130/292 (44%), Gaps = 19/292 (6%)
Query: 29 YNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF--SSSGKYMASASRDKT 86
++P +AT D +V +WD+ ++ F+G V V F + + S++ D
Sbjct: 3 FDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAA 62
Query: 87 VRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW---STHKHKFISSF 143
+R+W + AH V S+ FS+DG ++++ DK+ +W S + + F
Sbjct: 63 IRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVF 122
Query: 144 VGHTNWVRCAR-------MSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA 196
V + + G + D + ++W SG+C++T G G L
Sbjct: 123 ESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELT 182
Query: 197 W----HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVA-IHPSGSYILTASK 251
H +G V AT+ N+ LY+ R+ L + ++ ++E V V + P S+++ AS
Sbjct: 183 HCTLAHTAG-VVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASN 241
Query: 252 DGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
+K+ + L+ L GH V A++ G F+S D+ V IW+ N
Sbjct: 242 SPCLKVFE-LQTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMN 292
Score = 56.4 bits (130), Expect = 5e-07
Identities = 63/323 (19%), Positives = 127/323 (39%), Gaps = 21/323 (6%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+ A + +P + +S+ D ++ +W L+ H AV + FS+ G M S+ R
Sbjct: 42 LVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGR 101
Query: 84 DKTVRIW----------VPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
DK IW VP + V + S G +TA D +++W
Sbjct: 102 DKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWE 161
Query: 134 THKHKFISSFV---GHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
+ + + G + +++ ++ + + D + L+ S +
Sbjct: 162 AASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSE 221
Query: 191 HGLHLAW-HPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
L + + P +V VA++ +K+++++T + Q H + V + + G +
Sbjct: 222 EVLDVRFLGPEDSHVVVASNSPCLKVFELQT-SACQILHGHTDIVLALDVFRKGWLFASC 280
Query: 250 SKDGKMKILDLLEGHPIFTL---SGHNGPVNAVNFSPTGDTFSSAG-DDKLVFIWKTNFT 305
+KD ++I + + + + SGH V V S ++F G D V +W
Sbjct: 281 AKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKA 340
Query: 306 DLSSESKENEGQNMITGQRHLTE 328
LS + + G ++ Q H T+
Sbjct: 341 LLSKNTAPDNGPILL--QAHTTQ 361
Score = 51.2 bits (117), Expect = 2e-05
Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYIL--TASKD 252
+A+ P+ +A G V+++DI H ++ V VA HP + +L +++ D
Sbjct: 1 MAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATD 60
Query: 253 GKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+++ L + + L+ H V ++ FS G T S+G DK+ IW
Sbjct: 61 AAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIW 108
Score = 44.8 bits (101), Expect = 0.001
Identities = 57/281 (20%), Positives = 113/281 (40%), Gaps = 25/281 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR---FQGHDEAVM------ 67
L H +A+T+L ++ + + +S D ++WDL+ + F+ + AV+
Sbjct: 77 LTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEPV 136
Query: 68 -DVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFSSDGSKIIT 122
+ S G Y +A T+R+W +G +A Q + + ++T
Sbjct: 137 SQLGVKSPGLYFLTAGDQGTLRVW-EAASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLT 195
Query: 123 ASDDKVVKLWSTHKHKFISSFVGHTNWVRCAR-MSNDGSIIASCSDDKSTKLWNLDSGEC 181
A+ D + L+ + F G++ V R + + S + S+ K++ L + C
Sbjct: 196 ATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSAC 255
Query: 182 --IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNEAV-T 235
+H + D+ L L G A +V+++ + V S H +V T
Sbjct: 256 QILHGHTDIV---LALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGT 312
Query: 236 QVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPV 276
S+++T S+D +K+ L + + NGP+
Sbjct: 313 VCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPI 353
Score = 41.5 bits (93), Expect = 0.014
Identities = 40/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
G ++ L+ P ++ DN +L T R HD+ + V + + K +
Sbjct: 326 GSQDCTVKLWPLPKALLSKNTAPDNGPILLQAHTTQRC-----HDKDINSVAIAPNDKLL 380
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHK 138
A+ S+D+T ++W G+F H R +S + S+ H
Sbjct: 381 ATGSQDRTAKLWALPQCQLLGVFSGH----RVASGASSSLPWTRCWPRPQLMAPSSSGHS 436
Query: 139 FISSFVGHT--NWVRCARMS--NDGSIIASCSDDKSTKLWNLDSGECIHTY--KDLKGHG 192
S+ H + C +++ + G+ + S D KLW + + EC+ T + K G
Sbjct: 437 RTSAVSRHLRGTMLLCLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWG 496
Query: 193 LHLAW 197
L W
Sbjct: 497 LQAGW 501
>AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta
subunit-like protein protein.
Length = 305
Score = 93.5 bits (222), Expect = 3e-18
Identities = 45/191 (23%), Positives = 89/191 (46%)
Query: 27 LYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKT 86
L ++P+ Q +AT + V ++ + + Y + ++ + +S GKY+AS + D
Sbjct: 112 LAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGI 171
Query: 87 VRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGH 146
+ I+ + H+ +RS+ FS D ++TASDD +K++ + GH
Sbjct: 172 INIFAIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGH 231
Query: 147 TNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAV 206
+WV D + S S DKS K+ ++ + C+HT+ D + + ++ +G +
Sbjct: 232 ASWVLNVAFCPDDTHFVSSSSDKSVKVRDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVS 291
Query: 207 ATSHGNVKLYD 217
+ +YD
Sbjct: 292 VGDDQEIHIYD 302
Score = 91.1 bits (216), Expect = 2e-17
Identities = 73/297 (24%), Positives = 129/297 (43%), Gaps = 12/297 (4%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQ----IATSSLDNSVLLWDLRGTM--RSYRFQGHDEAV 66
L KQ + H +AI ++ + N ++ + T SLD+ V +W R + +GH V
Sbjct: 8 LFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGV 67
Query: 67 MDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
+ V S + AS+S D +R+ A ++ FS D + T +
Sbjct: 68 VSVDISHTLPIAASSSLDAHIRLRDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHV 127
Query: 127 KVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK 186
V ++ K S ++ S DG +AS + D ++ + +G+ +HT
Sbjct: 128 GKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFAIATGKLLHT-- 185
Query: 187 DLKGHGL---HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSG 243
L+GH + L + P + A+ G +K+YD++ NL S H V VA P
Sbjct: 186 -LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDD 244
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
++ +++S D +K+ D+ + T H V V ++ G S GDD+ + I+
Sbjct: 245 THFVSSSSDKSVKVRDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIY 301
Score = 79.4 bits (187), Expect = 6e-14
Identities = 53/213 (24%), Positives = 95/213 (44%), Gaps = 6/213 (2%)
Query: 102 KAHSQTVRSVQFSSDGSK----IITASDDKVVKLWSTHKHKFIS--SFVGHTNWVRCARM 155
+AH + SV + ++ + ++T S D +VK+W + S GH V +
Sbjct: 13 QAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDI 72
Query: 156 SNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKL 215
S+ I AS S D +L +L++G+ I + LA+ P Y+A T G V +
Sbjct: 73 SHTLPIAASSSLDAHIRLRDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNI 132
Query: 216 YDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGP 275
+ + + + + +A P G Y+ + + DG + I + G + TL GH P
Sbjct: 133 FGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFAIATGKLLHTLEGHAMP 192
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLS 308
+ ++ FSP +A DD + I+ +L+
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDVQHANLA 225
Score = 77.4 bits (182), Expect = 2e-13
Identities = 52/247 (21%), Positives = 107/247 (43%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
L+ L+GH+ + ++ + A+SSLD + L DL + + FS
Sbjct: 56 LQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLRDLENGKQIKSIDAGPVDAWTLAFS 115
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+Y+A+ + V I+ + + S+ +S DG + + + D ++ ++
Sbjct: 116 PDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG 192
+ K + + GH +R S D ++ + SDD K++++ T
Sbjct: 176 AIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWV 235
Query: 193 LHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKD 252
L++A+ P + ++S +VK+ D+ T V + H + V V + +GS I++ D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKSVKVRDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 253 GKMKILD 259
++ I D
Sbjct: 296 QEIHIYD 302
>BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 92.7 bits (220), Expect = 6e-18
Identities = 68/276 (24%), Positives = 117/276 (42%), Gaps = 6/276 (2%)
Query: 24 ITALYYNPND-QQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASAS 82
I AL P+D +I T D +V+++D +GH + V V F S + SAS
Sbjct: 224 ILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSAS 283
Query: 83 RDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
D T+RIW + +AH V + + G ++++SDD+ + ++
Sbjct: 284 PDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTK 343
Query: 143 FVGHTNW--VRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPS 200
T+ + CA+ DG I + + D K+W+L + + G +A+ +
Sbjct: 344 VTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSEN 403
Query: 201 GCYVAVATSHGNVKLYDIR-THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
G Y+A A +VKL+D+R N +N V + SG+Y+ D ++I
Sbjct: 404 GYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIYI 461
Query: 260 LLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ I + H+G V F +S G D+
Sbjct: 462 CKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDR 497
Score = 89.0 bits (211), Expect = 7e-17
Identities = 58/250 (23%), Positives = 116/250 (46%), Gaps = 11/250 (4%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
LKGH +T++ ++P+ + ++S D ++ +W + + H+ AV ++ ++G
Sbjct: 260 LKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD 319
Query: 77 YMASASRDKTVRIWV-PTVTGSTGMFKAHSQT----VRSVQFSSDGSKIITASDDKVVKL 131
Y+ S+S D + W + + K +T + QF DG T + D +K+
Sbjct: 320 YLLSSSDD---QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKI 376
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK-DLKG 190
W + +++F GH+ + S +G +A+ +DD S KLW+L + T + D
Sbjct: 377 WDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNF 436
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
L + SG Y+A+ + +V++Y + + +++ H+ T VA +I +
Sbjct: 437 EVKSLIFDQSGTYLALGGT--DVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTG 494
Query: 251 KDGKMKILDL 260
D +K L
Sbjct: 495 MDRSLKFYSL 504
Score = 85.8 bits (203), Expect = 7e-16
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 2/188 (1%)
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
SD +KI+T DK V ++ + +++ GHT V ++ S S D + ++W
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIW 291
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE-- 232
++ + C+ + + L+ H +G Y+ ++ DI+T ++ +
Sbjct: 292 SVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGC 351
Query: 233 AVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
++T HP G T + D ++KI DL E + GH+GP+ ++ FS G ++A
Sbjct: 352 SLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAA 411
Query: 293 DDKLVFIW 300
DD V +W
Sbjct: 412 DDSSVKLW 419
>BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 92.7 bits (220), Expect = 6e-18
Identities = 68/276 (24%), Positives = 117/276 (42%), Gaps = 6/276 (2%)
Query: 24 ITALYYNPND-QQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASAS 82
I AL P+D +I T D +V+++D +GH + V V F S + SAS
Sbjct: 224 ILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSAS 283
Query: 83 RDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
D T+RIW + +AH V + + G ++++SDD+ + ++
Sbjct: 284 PDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTK 343
Query: 143 FVGHTNW--VRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPS 200
T+ + CA+ DG I + + D K+W+L + + G +A+ +
Sbjct: 344 VTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSEN 403
Query: 201 GCYVAVATSHGNVKLYDIR-THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
G Y+A A +VKL+D+R N +N V + SG+Y+ D ++I
Sbjct: 404 GYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIYI 461
Query: 260 LLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ I + H+G V F +S G D+
Sbjct: 462 CKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDR 497
Score = 89.0 bits (211), Expect = 7e-17
Identities = 58/250 (23%), Positives = 116/250 (46%), Gaps = 11/250 (4%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
LKGH +T++ ++P+ + ++S D ++ +W + + H+ AV ++ ++G
Sbjct: 260 LKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD 319
Query: 77 YMASASRDKTVRIWV-PTVTGSTGMFKAHSQT----VRSVQFSSDGSKIITASDDKVVKL 131
Y+ S+S D + W + + K +T + QF DG T + D +K+
Sbjct: 320 YLLSSSDD---QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKI 376
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK-DLKG 190
W + +++F GH+ + S +G +A+ +DD S KLW+L + T + D
Sbjct: 377 WDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNF 436
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
L + SG Y+A+ + +V++Y + + +++ H+ T VA +I +
Sbjct: 437 EVKSLIFDQSGTYLALGGT--DVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTG 494
Query: 251 KDGKMKILDL 260
D +K L
Sbjct: 495 MDRSLKFYSL 504
Score = 85.8 bits (203), Expect = 7e-16
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 2/188 (1%)
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
SD +KI+T DK V ++ + +++ GHT V ++ S S D + ++W
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIW 291
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE-- 232
++ + C+ + + L+ H +G Y+ ++ DI+T ++ +
Sbjct: 292 SVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGC 351
Query: 233 AVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
++T HP G T + D ++KI DL E + GH+GP+ ++ FS G ++A
Sbjct: 352 SLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAA 411
Query: 293 DDKLVFIW 300
DD V +W
Sbjct: 412 DDSSVKLW 419
>BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 92.7 bits (220), Expect = 6e-18
Identities = 68/276 (24%), Positives = 117/276 (42%), Gaps = 6/276 (2%)
Query: 24 ITALYYNPND-QQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASAS 82
I AL P+D +I T D +V+++D +GH + V V F S + SAS
Sbjct: 224 ILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSAS 283
Query: 83 RDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
D T+RIW + +AH V + + G ++++SDD+ + ++
Sbjct: 284 PDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTK 343
Query: 143 FVGHTNW--VRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPS 200
T+ + CA+ DG I + + D K+W+L + + G +A+ +
Sbjct: 344 VTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSEN 403
Query: 201 GCYVAVATSHGNVKLYDIR-THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
G Y+A A +VKL+D+R N +N V + SG+Y+ D ++I
Sbjct: 404 GYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIYI 461
Query: 260 LLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ I + H+G V F +S G D+
Sbjct: 462 CKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDR 497
Score = 89.0 bits (211), Expect = 7e-17
Identities = 58/250 (23%), Positives = 116/250 (46%), Gaps = 11/250 (4%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
LKGH +T++ ++P+ + ++S D ++ +W + + H+ AV ++ ++G
Sbjct: 260 LKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD 319
Query: 77 YMASASRDKTVRIWV-PTVTGSTGMFKAHSQT----VRSVQFSSDGSKIITASDDKVVKL 131
Y+ S+S D + W + + K +T + QF DG T + D +K+
Sbjct: 320 YLLSSSDD---QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKI 376
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK-DLKG 190
W + +++F GH+ + S +G +A+ +DD S KLW+L + T + D
Sbjct: 377 WDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNF 436
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
L + SG Y+A+ + +V++Y + + +++ H+ T VA +I +
Sbjct: 437 EVKSLIFDQSGTYLALGGT--DVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTG 494
Query: 251 KDGKMKILDL 260
D +K L
Sbjct: 495 MDRSLKFYSL 504
Score = 85.8 bits (203), Expect = 7e-16
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 2/188 (1%)
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
SD +KI+T DK V ++ + +++ GHT V ++ S S D + ++W
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIW 291
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE-- 232
++ + C+ + + L+ H +G Y+ ++ DI+T ++ +
Sbjct: 292 SVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGC 351
Query: 233 AVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
++T HP G T + D ++KI DL E + GH+GP+ ++ FS G ++A
Sbjct: 352 SLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAA 411
Query: 293 DDKLVFIW 300
DD V +W
Sbjct: 412 DDSSVKLW 419
>AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein
NMP200 protein.
Length = 504
Score = 92.7 bits (220), Expect = 6e-18
Identities = 68/276 (24%), Positives = 117/276 (42%), Gaps = 6/276 (2%)
Query: 24 ITALYYNPND-QQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASAS 82
I AL P+D +I T D +V+++D +GH + V V F S + SAS
Sbjct: 224 ILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSAS 283
Query: 83 RDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISS 142
D T+RIW + +AH V + + G ++++SDD+ + ++
Sbjct: 284 PDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTK 343
Query: 143 FVGHTNW--VRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPS 200
T+ + CA+ DG I + + D K+W+L + + G +A+ +
Sbjct: 344 VTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSEN 403
Query: 201 GCYVAVATSHGNVKLYDIR-THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
G Y+A A +VKL+D+R N +N V + SG+Y+ D ++I
Sbjct: 404 GYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIYI 461
Query: 260 LLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
+ I + H+G V F +S G D+
Sbjct: 462 CKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDR 497
Score = 89.0 bits (211), Expect = 7e-17
Identities = 58/250 (23%), Positives = 116/250 (46%), Gaps = 11/250 (4%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
LKGH +T++ ++P+ + ++S D ++ +W + + H+ AV ++ ++G
Sbjct: 260 LKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD 319
Query: 77 YMASASRDKTVRIWV-PTVTGSTGMFKAHSQT----VRSVQFSSDGSKIITASDDKVVKL 131
Y+ S+S D + W + + K +T + QF DG T + D +K+
Sbjct: 320 YLLSSSDD---QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKI 376
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYK-DLKG 190
W + +++F GH+ + S +G +A+ +DD S KLW+L + T + D
Sbjct: 377 WDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNF 436
Query: 191 HGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTAS 250
L + SG Y+A+ + +V++Y + + +++ H+ T VA +I +
Sbjct: 437 EVKSLIFDQSGTYLALGGT--DVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTG 494
Query: 251 KDGKMKILDL 260
D +K L
Sbjct: 495 MDRSLKFYSL 504
Score = 85.8 bits (203), Expect = 7e-16
Identities = 47/188 (25%), Positives = 88/188 (46%), Gaps = 2/188 (1%)
Query: 115 SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
SD +KI+T DK V ++ + +++ GHT V ++ S S D + ++W
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIW 291
Query: 175 NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE-- 232
++ + C+ + + L+ H +G Y+ ++ DI+T ++ +
Sbjct: 292 SVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGC 351
Query: 233 AVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
++T HP G T + D ++KI DL E + GH+GP+ ++ FS G ++A
Sbjct: 352 SLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAA 411
Query: 293 DDKLVFIW 300
DD V +W
Sbjct: 412 DDSSVKLW 419
>BC039254-1|AAH39254.1| 893|Homo sapiens WDR47 protein protein.
Length = 893
Score = 91.1 bits (216), Expect = 2e-17
Identities = 75/270 (27%), Positives = 120/270 (44%), Gaps = 21/270 (7%)
Query: 54 MRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWV-------PTVTGSTGMFKAHSQ 106
+R R + H ++ V +S G+ +A+ S DK V++ TV+G F H
Sbjct: 624 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATVSGPDLEFSMHDG 683
Query: 107 TVRSVQF----SSDGSKIITA-SDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSI 161
T+R + F S G+ +I+A + D + + + + + GHT + A + G +
Sbjct: 684 TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI-LALYTWSGWM 742
Query: 162 IASCSDDKSTKLWNLDSGECIH----TYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYD 217
IAS S DK+ + W+L C+ T+ +A PSG +A + LYD
Sbjct: 743 IASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYD 802
Query: 218 IRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKIL----DLLEGHPIFTLSGHN 273
IR +VQ Y H+ V V P Y+LT S D K+K+ DL + PI + H
Sbjct: 803 IRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHK 862
Query: 274 GPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
V + +F S+ D+ V +W N
Sbjct: 863 DKVIQCRWHTQDLSFLSSSADRTVTLWTYN 892
Score = 50.0 bits (114), Expect = 4e-05
Identities = 56/267 (20%), Positives = 103/267 (38%), Gaps = 22/267 (8%)
Query: 7 TTPEPCLK-KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRG-------TMRSYR 58
T +P ++ K+ K HK +I + ++P Q +AT S D V + +
Sbjct: 618 TPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATVSGPDLE 677
Query: 59 FQGHDEAVMDVTF----SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ-F 113
F HD + D+ F S G + SA I+ G+ T + +
Sbjct: 678 FSMHDGTIRDLAFMEGPESGGAILISAGAG-DCNIYTTDCQRGQGLHALSGHTGHILALY 736
Query: 114 SSDGSKIITASDDKVVKLWSTHKHKFI----SSFVGHTNWVRCARMSNDGSIIASCSDDK 169
+ G I + S DK V+ W + ++F G + V + G ++A+ +D
Sbjct: 737 TWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDS 796
Query: 170 STKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR---THNL-VQ 225
S L+++ G + +Y + + P Y+ + +K+ D++ T L +
Sbjct: 797 SCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIM 856
Query: 226 YYSIHNEAVTQVAIHPSGSYILTASKD 252
H + V Q H L++S D
Sbjct: 857 VVGEHKDKVIQCRWHTQDLSFLSSSAD 883
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
G +A+ ++ +P+ + +AT D+S +L+D+RG + H V V FS Y+
Sbjct: 772 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYL 831
Query: 79 ASASRDKTVRI--WVPTVTGSTGMFKA--HSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S D +++ +T + H V ++ + +++S D+ V LW+
Sbjct: 832 LTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWT 890
>AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein.
Length = 1336
Score = 91.1 bits (216), Expect = 2e-17
Identities = 61/242 (25%), Positives = 110/242 (45%), Gaps = 11/242 (4%)
Query: 66 VMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASD 125
V V ++ G+ + + + +W + +AH VR++ +S + ++TA
Sbjct: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADH 181
Query: 126 DKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
VK W ++ + + F H +R A S + A+CSDD + ++W D C H
Sbjct: 182 GGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIW--DFLRC-HEE 237
Query: 186 KDLKGHGLHLA---WHPSGCYVAVAT--SHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIH 240
+ L+GHG + WHP+ V + S +K +D +T + H V +V ++
Sbjct: 238 RILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN 297
Query: 241 PSGSYILTASKDGKMKILDLLE-GHPIFTLSGHNGPVNAVNFSPTGD-TFSSAGDDKLVF 298
+G+++LTAS+D K+ D+ + GH AV + P + F+S G D +
Sbjct: 298 LNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLL 357
Query: 299 IW 300
W
Sbjct: 358 FW 359
Score = 88.2 bits (209), Expect = 1e-16
Identities = 70/317 (22%), Positives = 131/317 (41%), Gaps = 11/317 (3%)
Query: 21 KNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMAS 80
K + + + P +++ T + LW+ Q HD V +T+S + +M +
Sbjct: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
Query: 81 ASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFI 140
A V+ W + + MF+AH + +R FS +K T SDD V++W +
Sbjct: 179 ADHGGYVKYWQSNM-NNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEE 237
Query: 141 SSFVGHTNWVRCARMSNDGSIIASCSDD--KSTKLWNLDSGECIHTYKDLKGHGLHLAWH 198
GH V+C ++ S S D + K W+ +G+ + T K + + +
Sbjct: 238 RILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN 297
Query: 199 PSGCYVAVATSHGNVKLYDIRT-HNLVQYYSIHNEAVTQVAIHP-SGSYILTASKDGKMK 256
+G ++ A+ KL+DIR +Q + H + T VA HP + DG +
Sbjct: 298 LNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLL 357
Query: 257 ILDL-LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENE 315
+ +E H G + ++ + P G S +D W N + ++
Sbjct: 358 FWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRP--GDKMRDRY 415
Query: 316 GQNMITGQRHLTEEGID 332
N++ G ++E+G++
Sbjct: 416 NLNLLPG---MSEDGVE 429
Score = 72.5 bits (170), Expect = 6e-12
Identities = 53/193 (27%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K + HK AI ++P D + AT S D +V +WD +GH V V + +
Sbjct: 196 KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPT 255
Query: 75 GKYMASASRD--KTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+ S S+D + ++ W P S AH TV V+ + +G+ ++TAS D + KL+
Sbjct: 256 KGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLF 315
Query: 133 STHKHK-FISSFVGHTNWVRCARMS--NDGSIIASCSDDKSTKLWNLDSGECIHTYKDL- 188
K + F GH ++G + AS D S W++ + + +
Sbjct: 316 DIRNLKEELQVFRGHKKEATAVAWHPVHEG-LFASGGSDGSLLFWHVGVEKEVGGMEMAH 374
Query: 189 KGHGLHLAWHPSG 201
+G LAWHP G
Sbjct: 375 EGMIWSLAWHPLG 387
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/155 (25%), Positives = 65/155 (41%), Gaps = 11/155 (7%)
Query: 147 TNWVRC----ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHP 199
TN V+C R + +G + + + LWN G + L+ H + W
Sbjct: 115 TNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWN---GLTFNFETILQAHDSPVRAMTWSH 171
Query: 200 SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
+ ++ A G VK + +N V+ + H EA+ + + P+ + T S DG ++I D
Sbjct: 172 NDMWMLTADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
Query: 260 LLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDD 294
L H L GH V V++ PT S D
Sbjct: 231 FLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKD 265
>AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein.
Length = 1336
Score = 91.1 bits (216), Expect = 2e-17
Identities = 61/242 (25%), Positives = 110/242 (45%), Gaps = 11/242 (4%)
Query: 66 VMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASD 125
V V ++ G+ + + + +W + +AH VR++ +S + ++TA
Sbjct: 122 VFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADH 181
Query: 126 DKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
VK W ++ + + F H +R A S + A+CSDD + ++W D C H
Sbjct: 182 GGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIW--DFLRC-HEE 237
Query: 186 KDLKGHGLHLA---WHPSGCYVAVAT--SHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIH 240
+ L+GHG + WHP+ V + S +K +D +T + H V +V ++
Sbjct: 238 RILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN 297
Query: 241 PSGSYILTASKDGKMKILDLLE-GHPIFTLSGHNGPVNAVNFSPTGD-TFSSAGDDKLVF 298
+G+++LTAS+D K+ D+ + GH AV + P + F+S G D +
Sbjct: 298 LNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLL 357
Query: 299 IW 300
W
Sbjct: 358 FW 359
Score = 88.2 bits (209), Expect = 1e-16
Identities = 70/317 (22%), Positives = 131/317 (41%), Gaps = 11/317 (3%)
Query: 21 KNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMAS 80
K + + + P +++ T + LW+ Q HD V +T+S + +M +
Sbjct: 119 KCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLT 178
Query: 81 ASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFI 140
A V+ W + + MF+AH + +R FS +K T SDD V++W +
Sbjct: 179 ADHGGYVKYWQSNM-NNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEE 237
Query: 141 SSFVGHTNWVRCARMSNDGSIIASCSDD--KSTKLWNLDSGECIHTYKDLKGHGLHLAWH 198
GH V+C ++ S S D + K W+ +G+ + T K + + +
Sbjct: 238 RILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN 297
Query: 199 PSGCYVAVATSHGNVKLYDIRT-HNLVQYYSIHNEAVTQVAIHP-SGSYILTASKDGKMK 256
+G ++ A+ KL+DIR +Q + H + T VA HP + DG +
Sbjct: 298 LNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLL 357
Query: 257 ILDL-LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTDLSSESKENE 315
+ +E H G + ++ + P G S +D W N + ++
Sbjct: 358 FWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRP--GDKMRDRY 415
Query: 316 GQNMITGQRHLTEEGID 332
N++ G ++E+G++
Sbjct: 416 NLNLLPG---MSEDGVE 429
Score = 72.5 bits (170), Expect = 6e-12
Identities = 53/193 (27%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSS 74
K + HK AI ++P D + AT S D +V +WD +GH V V + +
Sbjct: 196 KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPT 255
Query: 75 GKYMASASRD--KTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+ S S+D + ++ W P S AH TV V+ + +G+ ++TAS D + KL+
Sbjct: 256 KGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLF 315
Query: 133 STHKHK-FISSFVGHTNWVRCARMS--NDGSIIASCSDDKSTKLWNLDSGECIHTYKDL- 188
K + F GH ++G + AS D S W++ + + +
Sbjct: 316 DIRNLKEELQVFRGHKKEATAVAWHPVHEG-LFASGGSDGSLLFWHVGVEKEVGGMEMAH 374
Query: 189 KGHGLHLAWHPSG 201
+G LAWHP G
Sbjct: 375 EGMIWSLAWHPLG 387
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/155 (25%), Positives = 65/155 (41%), Gaps = 11/155 (7%)
Query: 147 TNWVRC----ARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH---LAWHP 199
TN V+C R + +G + + + LWN G + L+ H + W
Sbjct: 115 TNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWN---GLTFNFETILQAHDSPVRAMTWSH 171
Query: 200 SGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILD 259
+ ++ A G VK + +N V+ + H EA+ + + P+ + T S DG ++I D
Sbjct: 172 NDMWMLTADHGGYVKYWQSNMNN-VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWD 230
Query: 260 LLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDD 294
L H L GH V V++ PT S D
Sbjct: 231 FLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKD 265
>BX679664-5|CAH71327.1| 919|Homo sapiens WD repeat domain 47
protein.
Length = 919
Score = 90.6 bits (215), Expect = 2e-17
Identities = 74/268 (27%), Positives = 118/268 (44%), Gaps = 19/268 (7%)
Query: 54 MRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIW-----VPTVTGSTGMFKAHSQTV 108
+R R + H ++ V +S G+ +A+ S DK V++ TG F H T+
Sbjct: 652 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTI 711
Query: 109 RSVQF----SSDGSKIITA-SDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
R + F S G+ +I+A + D + + + + + GHT + A + G +IA
Sbjct: 712 RDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI-LALYTWSGWMIA 770
Query: 164 SCSDDKSTKLWNLDSGECIH----TYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S S DK+ + W+L C+ T+ +A PSG +A + LYDIR
Sbjct: 771 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR 830
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKIL----DLLEGHPIFTLSGHNGP 275
+VQ Y H+ V V P Y+LT S D K+K+ DL + PI + H
Sbjct: 831 GGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDK 890
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
V + +F S+ D+ V +W N
Sbjct: 891 VIQCRWHTQDLSFLSSSADRTVTLWTYN 918
Score = 53.2 bits (122), Expect = 4e-06
Identities = 57/265 (21%), Positives = 103/265 (38%), Gaps = 20/265 (7%)
Query: 7 TTPEPCLK-KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRFQ 60
T +P ++ K+ K HK +I + ++P Q +AT S D V + T F
Sbjct: 646 TPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFS 705
Query: 61 GHDEAVMDVTF----SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ-FSS 115
HD + D+ F S G + SA I+ G+ T + ++
Sbjct: 706 MHDGTIRDLAFMEGPESGGAILISAGAG-DCNIYTTDCQRGQGLHALSGHTGHILALYTW 764
Query: 116 DGSKIITASDDKVVKLWSTHKHKFI----SSFVGHTNWVRCARMSNDGSIIASCSDDKST 171
G I + S DK V+ W + ++F G + V + G ++A+ +D S
Sbjct: 765 SGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSC 824
Query: 172 KLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR---THNL-VQYY 227
L+++ G + +Y + + P Y+ + +K+ D++ T L +
Sbjct: 825 MLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVV 884
Query: 228 SIHNEAVTQVAIHPSGSYILTASKD 252
H + V Q H L++S D
Sbjct: 885 GEHKDKVIQCRWHTQDLSFLSSSAD 909
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
G +A+ ++ +P+ + +AT D+S +L+D+RG + H V V FS Y+
Sbjct: 798 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYL 857
Query: 79 ASASRDKTVRI--WVPTVTGSTGMFKA--HSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S D +++ +T + H V ++ + +++S D+ V LW+
Sbjct: 858 LTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWT 916
>BX679664-4|CAH71326.1| 920|Homo sapiens WD repeat domain 47
protein.
Length = 920
Score = 90.6 bits (215), Expect = 2e-17
Identities = 74/268 (27%), Positives = 118/268 (44%), Gaps = 19/268 (7%)
Query: 54 MRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIW-----VPTVTGSTGMFKAHSQTV 108
+R R + H ++ V +S G+ +A+ S DK V++ TG F H T+
Sbjct: 653 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTI 712
Query: 109 RSVQF----SSDGSKIITA-SDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
R + F S G+ +I+A + D + + + + + GHT + A + G +IA
Sbjct: 713 RDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI-LALYTWSGWMIA 771
Query: 164 SCSDDKSTKLWNLDSGECIH----TYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S S DK+ + W+L C+ T+ +A PSG +A + LYDIR
Sbjct: 772 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR 831
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKIL----DLLEGHPIFTLSGHNGP 275
+VQ Y H+ V V P Y+LT S D K+K+ DL + PI + H
Sbjct: 832 GGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDK 891
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
V + +F S+ D+ V +W N
Sbjct: 892 VIQCRWHTQDLSFLSSSADRTVTLWTYN 919
Score = 53.2 bits (122), Expect = 4e-06
Identities = 57/265 (21%), Positives = 103/265 (38%), Gaps = 20/265 (7%)
Query: 7 TTPEPCLK-KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRFQ 60
T +P ++ K+ K HK +I + ++P Q +AT S D V + T F
Sbjct: 647 TPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFS 706
Query: 61 GHDEAVMDVTF----SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ-FSS 115
HD + D+ F S G + SA I+ G+ T + ++
Sbjct: 707 MHDGTIRDLAFMEGPESGGAILISAGAG-DCNIYTTDCQRGQGLHALSGHTGHILALYTW 765
Query: 116 DGSKIITASDDKVVKLWSTHKHKFI----SSFVGHTNWVRCARMSNDGSIIASCSDDKST 171
G I + S DK V+ W + ++F G + V + G ++A+ +D S
Sbjct: 766 SGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSC 825
Query: 172 KLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR---THNL-VQYY 227
L+++ G + +Y + + P Y+ + +K+ D++ T L +
Sbjct: 826 MLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVV 885
Query: 228 SIHNEAVTQVAIHPSGSYILTASKD 252
H + V Q H L++S D
Sbjct: 886 GEHKDKVIQCRWHTQDLSFLSSSAD 910
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
G +A+ ++ +P+ + +AT D+S +L+D+RG + H V V FS Y+
Sbjct: 799 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYL 858
Query: 79 ASASRDKTVRI--WVPTVTGSTGMFKA--HSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S D +++ +T + H V ++ + +++S D+ V LW+
Sbjct: 859 LTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWT 917
>BX679664-3|CAH71325.1| 891|Homo sapiens WD repeat domain 47
protein.
Length = 891
Score = 90.6 bits (215), Expect = 2e-17
Identities = 74/268 (27%), Positives = 118/268 (44%), Gaps = 19/268 (7%)
Query: 54 MRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIW-----VPTVTGSTGMFKAHSQTV 108
+R R + H ++ V +S G+ +A+ S DK V++ TG F H T+
Sbjct: 624 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTI 683
Query: 109 RSVQF----SSDGSKIITA-SDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
R + F S G+ +I+A + D + + + + + GHT + A + G +IA
Sbjct: 684 RDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI-LALYTWSGWMIA 742
Query: 164 SCSDDKSTKLWNLDSGECIH----TYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S S DK+ + W+L C+ T+ +A PSG +A + LYDIR
Sbjct: 743 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR 802
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKIL----DLLEGHPIFTLSGHNGP 275
+VQ Y H+ V V P Y+LT S D K+K+ DL + PI + H
Sbjct: 803 GGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDK 862
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
V + +F S+ D+ V +W N
Sbjct: 863 VIQCRWHTQDLSFLSSSADRTVTLWTYN 890
Score = 53.2 bits (122), Expect = 4e-06
Identities = 57/265 (21%), Positives = 103/265 (38%), Gaps = 20/265 (7%)
Query: 7 TTPEPCLK-KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRFQ 60
T +P ++ K+ K HK +I + ++P Q +AT S D V + T F
Sbjct: 618 TPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFS 677
Query: 61 GHDEAVMDVTF----SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ-FSS 115
HD + D+ F S G + SA I+ G+ T + ++
Sbjct: 678 MHDGTIRDLAFMEGPESGGAILISAGAG-DCNIYTTDCQRGQGLHALSGHTGHILALYTW 736
Query: 116 DGSKIITASDDKVVKLWSTHKHKFI----SSFVGHTNWVRCARMSNDGSIIASCSDDKST 171
G I + S DK V+ W + ++F G + V + G ++A+ +D S
Sbjct: 737 SGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSC 796
Query: 172 KLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR---THNL-VQYY 227
L+++ G + +Y + + P Y+ + +K+ D++ T L +
Sbjct: 797 MLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVV 856
Query: 228 SIHNEAVTQVAIHPSGSYILTASKD 252
H + V Q H L++S D
Sbjct: 857 GEHKDKVIQCRWHTQDLSFLSSSAD 881
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
G +A+ ++ +P+ + +AT D+S +L+D+RG + H V V FS Y+
Sbjct: 770 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYL 829
Query: 79 ASASRDKTVRI--WVPTVTGSTGMFKA--HSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S D +++ +T + H V ++ + +++S D+ V LW+
Sbjct: 830 LTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWT 888
>BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein.
Length = 452
Score = 90.6 bits (215), Expect = 2e-17
Identities = 54/193 (27%), Positives = 93/193 (48%), Gaps = 8/193 (4%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRF-QGHDEAVMDVTFSSSGKYM 78
H +IT+ ++P+ Q++A+ SLD + +WD+ + H A+ + F+ SG ++
Sbjct: 255 HTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFL 314
Query: 79 ASASRDKTVRIW-VPT-----VTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
++S DK ++IW V T + + H +V S F+ D S +I+ D+ V +W
Sbjct: 315 CTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIW 374
Query: 133 STHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS-GECIHTYKDLKGH 191
+ S GH +WV +SN+ I S S D++ +LWN++ E K K
Sbjct: 375 DVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWNIEEIDEIPLVIKYKKAV 434
Query: 192 GLHLAWHPSGCYV 204
GL L Y+
Sbjct: 435 GLKLKQEKKEAYL 447
Score = 85.8 bits (203), Expect = 7e-16
Identities = 72/303 (23%), Positives = 134/303 (44%), Gaps = 13/303 (4%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEA-VMDVTFSS 73
K L GH++A++ ++ +D ++ + S D +V LWD F+ +A V++ + +
Sbjct: 122 KILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITG 181
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQT-VRSVQFSSDGSKIITASD-DKVVKL 131
+ +AS DKTVR W TG ++K T + S +FS DG +++ D D + +
Sbjct: 182 DSSRVIAASYDKTVRAW-DLETGKL-LWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICI 239
Query: 132 WSTHKHKFISSFVGH-TNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
+S H T + D +AS S D+ K+W++ S + T
Sbjct: 240 MDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHS 299
Query: 191 HGL-HLAWHPSGCYVAVATSHGNVKLYDIRTHNL------VQYYSIHNEAVTQVAIHPSG 243
+ + + + SG ++ ++ N+K++++ T V H +V+
Sbjct: 300 NAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDS 359
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
S++++ D + I D+ EG+ +L GHN V V S SA D+ + +W
Sbjct: 360 SFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWNIE 419
Query: 304 FTD 306
D
Sbjct: 420 EID 422
Score = 58.0 bits (134), Expect = 1e-07
Identities = 36/132 (27%), Positives = 62/132 (46%), Gaps = 6/132 (4%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRS-----YRFQG 61
T + L K H NAI+ + + + TSS D ++ +W++ G R+ QG
Sbjct: 286 TSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNCGACVTLMQG 345
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H+ +V F+ ++ S D+TV IW K H+ V V S++ I+
Sbjct: 346 HEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNNKKWIL 405
Query: 122 TASDDKVVKLWS 133
+AS D+ ++LW+
Sbjct: 406 SASKDRTMRLWN 417
>AL449266-4|CAI14352.1| 891|Homo sapiens WD repeat domain 47
protein.
Length = 891
Score = 90.6 bits (215), Expect = 2e-17
Identities = 74/268 (27%), Positives = 118/268 (44%), Gaps = 19/268 (7%)
Query: 54 MRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIW-----VPTVTGSTGMFKAHSQTV 108
+R R + H ++ V +S G+ +A+ S DK V++ TG F H T+
Sbjct: 624 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTI 683
Query: 109 RSVQF----SSDGSKIITA-SDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
R + F S G+ +I+A + D + + + + + GHT + A + G +IA
Sbjct: 684 RDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI-LALYTWSGWMIA 742
Query: 164 SCSDDKSTKLWNLDSGECIH----TYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S S DK+ + W+L C+ T+ +A PSG +A + LYDIR
Sbjct: 743 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR 802
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKIL----DLLEGHPIFTLSGHNGP 275
+VQ Y H+ V V P Y+LT S D K+K+ DL + PI + H
Sbjct: 803 GGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDK 862
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
V + +F S+ D+ V +W N
Sbjct: 863 VIQCRWHTQDLSFLSSSADRTVTLWTYN 890
Score = 53.2 bits (122), Expect = 4e-06
Identities = 57/265 (21%), Positives = 103/265 (38%), Gaps = 20/265 (7%)
Query: 7 TTPEPCLK-KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRFQ 60
T +P ++ K+ K HK +I + ++P Q +AT S D V + T F
Sbjct: 618 TPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFS 677
Query: 61 GHDEAVMDVTF----SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ-FSS 115
HD + D+ F S G + SA I+ G+ T + ++
Sbjct: 678 MHDGTIRDLAFMEGPESGGAILISAGAG-DCNIYTTDCQRGQGLHALSGHTGHILALYTW 736
Query: 116 DGSKIITASDDKVVKLWSTHKHKFI----SSFVGHTNWVRCARMSNDGSIIASCSDDKST 171
G I + S DK V+ W + ++F G + V + G ++A+ +D S
Sbjct: 737 SGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSC 796
Query: 172 KLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR---THNL-VQYY 227
L+++ G + +Y + + P Y+ + +K+ D++ T L +
Sbjct: 797 MLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVV 856
Query: 228 SIHNEAVTQVAIHPSGSYILTASKD 252
H + V Q H L++S D
Sbjct: 857 GEHKDKVIQCRWHTQDLSFLSSSAD 881
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
G +A+ ++ +P+ + +AT D+S +L+D+RG + H V V FS Y+
Sbjct: 770 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYL 829
Query: 79 ASASRDKTVRI--WVPTVTGSTGMFKA--HSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S D +++ +T + H V ++ + +++S D+ V LW+
Sbjct: 830 LTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWT 888
>AL449266-3|CAI14353.1| 919|Homo sapiens WD repeat domain 47
protein.
Length = 919
Score = 90.6 bits (215), Expect = 2e-17
Identities = 74/268 (27%), Positives = 118/268 (44%), Gaps = 19/268 (7%)
Query: 54 MRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIW-----VPTVTGSTGMFKAHSQTV 108
+R R + H ++ V +S G+ +A+ S DK V++ TG F H T+
Sbjct: 652 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTI 711
Query: 109 RSVQF----SSDGSKIITA-SDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
R + F S G+ +I+A + D + + + + + GHT + A + G +IA
Sbjct: 712 RDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI-LALYTWSGWMIA 770
Query: 164 SCSDDKSTKLWNLDSGECIH----TYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S S DK+ + W+L C+ T+ +A PSG +A + LYDIR
Sbjct: 771 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR 830
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKIL----DLLEGHPIFTLSGHNGP 275
+VQ Y H+ V V P Y+LT S D K+K+ DL + PI + H
Sbjct: 831 GGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDK 890
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
V + +F S+ D+ V +W N
Sbjct: 891 VIQCRWHTQDLSFLSSSADRTVTLWTYN 918
Score = 53.2 bits (122), Expect = 4e-06
Identities = 57/265 (21%), Positives = 103/265 (38%), Gaps = 20/265 (7%)
Query: 7 TTPEPCLK-KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRFQ 60
T +P ++ K+ K HK +I + ++P Q +AT S D V + T F
Sbjct: 646 TPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFS 705
Query: 61 GHDEAVMDVTF----SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ-FSS 115
HD + D+ F S G + SA I+ G+ T + ++
Sbjct: 706 MHDGTIRDLAFMEGPESGGAILISAGAG-DCNIYTTDCQRGQGLHALSGHTGHILALYTW 764
Query: 116 DGSKIITASDDKVVKLWSTHKHKFI----SSFVGHTNWVRCARMSNDGSIIASCSDDKST 171
G I + S DK V+ W + ++F G + V + G ++A+ +D S
Sbjct: 765 SGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSC 824
Query: 172 KLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR---THNL-VQYY 227
L+++ G + +Y + + P Y+ + +K+ D++ T L +
Sbjct: 825 MLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVV 884
Query: 228 SIHNEAVTQVAIHPSGSYILTASKD 252
H + V Q H L++S D
Sbjct: 885 GEHKDKVIQCRWHTQDLSFLSSSAD 909
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
G +A+ ++ +P+ + +AT D+S +L+D+RG + H V V FS Y+
Sbjct: 798 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYL 857
Query: 79 ASASRDKTVRI--WVPTVTGSTGMFKA--HSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S D +++ +T + H V ++ + +++S D+ V LW+
Sbjct: 858 LTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWT 916
>AL449266-2|CAI14351.1| 920|Homo sapiens WD repeat domain 47
protein.
Length = 920
Score = 90.6 bits (215), Expect = 2e-17
Identities = 74/268 (27%), Positives = 118/268 (44%), Gaps = 19/268 (7%)
Query: 54 MRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIW-----VPTVTGSTGMFKAHSQTV 108
+R R + H ++ V +S G+ +A+ S DK V++ TG F H T+
Sbjct: 653 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTI 712
Query: 109 RSVQF----SSDGSKIITA-SDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
R + F S G+ +I+A + D + + + + + GHT + A + G +IA
Sbjct: 713 RDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI-LALYTWSGWMIA 771
Query: 164 SCSDDKSTKLWNLDSGECIH----TYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S S DK+ + W+L C+ T+ +A PSG +A + LYDIR
Sbjct: 772 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR 831
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKIL----DLLEGHPIFTLSGHNGP 275
+VQ Y H+ V V P Y+LT S D K+K+ DL + PI + H
Sbjct: 832 GGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDK 891
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
V + +F S+ D+ V +W N
Sbjct: 892 VIQCRWHTQDLSFLSSSADRTVTLWTYN 919
Score = 53.2 bits (122), Expect = 4e-06
Identities = 57/265 (21%), Positives = 103/265 (38%), Gaps = 20/265 (7%)
Query: 7 TTPEPCLK-KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRFQ 60
T +P ++ K+ K HK +I + ++P Q +AT S D V + T F
Sbjct: 647 TPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFS 706
Query: 61 GHDEAVMDVTF----SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ-FSS 115
HD + D+ F S G + SA I+ G+ T + ++
Sbjct: 707 MHDGTIRDLAFMEGPESGGAILISAGAG-DCNIYTTDCQRGQGLHALSGHTGHILALYTW 765
Query: 116 DGSKIITASDDKVVKLWSTHKHKFI----SSFVGHTNWVRCARMSNDGSIIASCSDDKST 171
G I + S DK V+ W + ++F G + V + G ++A+ +D S
Sbjct: 766 SGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSC 825
Query: 172 KLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR---THNL-VQYY 227
L+++ G + +Y + + P Y+ + +K+ D++ T L +
Sbjct: 826 MLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVV 885
Query: 228 SIHNEAVTQVAIHPSGSYILTASKD 252
H + V Q H L++S D
Sbjct: 886 GEHKDKVIQCRWHTQDLSFLSSSAD 910
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
G +A+ ++ +P+ + +AT D+S +L+D+RG + H V V FS Y+
Sbjct: 799 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYL 858
Query: 79 ASASRDKTVRI--WVPTVTGSTGMFKA--HSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S D +++ +T + H V ++ + +++S D+ V LW+
Sbjct: 859 LTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWT 917
>AB020700-1|BAA74916.2| 974|Homo sapiens KIAA0893 protein protein.
Length = 974
Score = 90.6 bits (215), Expect = 2e-17
Identities = 74/268 (27%), Positives = 118/268 (44%), Gaps = 19/268 (7%)
Query: 54 MRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIW-----VPTVTGSTGMFKAHSQTV 108
+R R + H ++ V +S G+ +A+ S DK V++ TG F H T+
Sbjct: 707 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTI 766
Query: 109 RSVQF----SSDGSKIITA-SDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
R + F S G+ +I+A + D + + + + + GHT + A + G +IA
Sbjct: 767 RDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI-LALYTWSGWMIA 825
Query: 164 SCSDDKSTKLWNLDSGECIH----TYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S S DK+ + W+L C+ T+ +A PSG +A + LYDIR
Sbjct: 826 SGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR 885
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKIL----DLLEGHPIFTLSGHNGP 275
+VQ Y H+ V V P Y+LT S D K+K+ DL + PI + H
Sbjct: 886 GGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDK 945
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
V + +F S+ D+ V +W N
Sbjct: 946 VIQCRWHTQDLSFLSSSADRTVTLWTYN 973
Score = 53.2 bits (122), Expect = 4e-06
Identities = 57/265 (21%), Positives = 103/265 (38%), Gaps = 20/265 (7%)
Query: 7 TTPEPCLK-KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRFQ 60
T +P ++ K+ K HK +I + ++P Q +AT S D V + T F
Sbjct: 701 TPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFS 760
Query: 61 GHDEAVMDVTF----SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ-FSS 115
HD + D+ F S G + SA I+ G+ T + ++
Sbjct: 761 MHDGTIRDLAFMEGPESGGAILISAGAG-DCNIYTTDCQRGQGLHALSGHTGHILALYTW 819
Query: 116 DGSKIITASDDKVVKLWSTHKHKFI----SSFVGHTNWVRCARMSNDGSIIASCSDDKST 171
G I + S DK V+ W + ++F G + V + G ++A+ +D S
Sbjct: 820 SGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSC 879
Query: 172 KLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR---THNL-VQYY 227
L+++ G + +Y + + P Y+ + +K+ D++ T L +
Sbjct: 880 MLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVV 939
Query: 228 SIHNEAVTQVAIHPSGSYILTASKD 252
H + V Q H L++S D
Sbjct: 940 GEHKDKVIQCRWHTQDLSFLSSSAD 964
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
G +A+ ++ +P+ + +AT D+S +L+D+RG + H V V FS Y+
Sbjct: 853 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYL 912
Query: 79 ASASRDKTVRI--WVPTVTGSTGMFKA--HSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S D +++ +T + H V ++ + +++S D+ V LW+
Sbjct: 913 LTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWT 971
>X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer complex
protein.
Length = 906
Score = 90.2 bits (214), Expect = 3e-17
Identities = 66/252 (26%), Positives = 117/252 (46%), Gaps = 10/252 (3%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
+K++L + + ++ +P + + S + SV +W+ F+ D V F
Sbjct: 7 IKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFV 66
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+ ++ + + D +R++ MF+AHS +R + I+T+SDD ++KLW
Sbjct: 67 ARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 126
Query: 133 STHKHKFISS-FVGHTNWV-RCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
K S F GHT++V + D + AS S D++ K+W L S T L+G
Sbjct: 127 DWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFT---LEG 183
Query: 191 H--GLHLAWHPSG---CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSY 245
H G++ + SG Y+ VK++D + VQ H + V+ + HP
Sbjct: 184 HEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPI 243
Query: 246 ILTASKDGKMKI 257
I+T S+DG ++I
Sbjct: 244 IITGSEDGTVRI 255
Score = 81.4 bits (192), Expect = 1e-14
Identities = 45/162 (27%), Positives = 78/162 (48%), Gaps = 4/162 (2%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFS-SSG 75
+ H + I + +P I TSS D + LWD + S F+GH VM + +
Sbjct: 96 EAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDN 155
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK--IITASDDKVVKLWS 133
ASAS D+T+++W + + H + V + + S G K +I+ +DD++VK+W
Sbjct: 156 NQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWD 215
Query: 134 THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
+ + GH V CA + II + S+D + ++W+
Sbjct: 216 YQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH 257
Score = 74.1 bits (174), Expect = 2e-12
Identities = 58/243 (23%), Positives = 109/243 (44%), Gaps = 5/243 (2%)
Query: 103 AHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSII 162
A S V+SV ++ + + V +W+ + +F VR A+ + +
Sbjct: 13 ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWV 72
Query: 163 ASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI-RTH 221
+ +DD +++N ++ E +H ++ + +A HP+ ++ ++ +KL+D +
Sbjct: 73 VTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKW 132
Query: 222 NLVQYYSIHNEAVTQVAIHPS-GSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ Q + H V Q+ I+P + +AS D +K+ L P FTL GH VN ++
Sbjct: 133 SCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCID 192
Query: 281 FSPTGDT--FSSAGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENG 338
+ GD S DD+LV IW ++ E QN+ H I T +E+G
Sbjct: 193 YYSGGDKPYLISGADDRLVKIWDYQ-NKTCVQTLEGHAQNVSCASFHPELPIIITGSEDG 251
Query: 339 QIQ 341
++
Sbjct: 252 TVR 254
Score = 69.3 bits (162), Expect = 6e-11
Identities = 50/256 (19%), Positives = 110/256 (42%), Gaps = 4/256 (1%)
Query: 58 RFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDG 117
+ + V V + +M ++ + +V +W F+ VR+ +F +
Sbjct: 10 KLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARK 69
Query: 118 SKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
+ ++T +DD +++++ + + + F H++++RC + I + SDD KLW+ D
Sbjct: 70 NWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWD 129
Query: 178 SG-ECIHTYKDLKGHGLHLAWHPS-GCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
C ++ + + + +P A A+ +K++ + + + H + V
Sbjct: 130 KKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVN 189
Query: 236 QVAIHPSGS--YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGD 293
+ + G Y+++ + D +KI D + TL GH V+ +F P + +
Sbjct: 190 CIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSE 249
Query: 294 DKLVFIWKTNFTDLSS 309
D V IW ++ L S
Sbjct: 250 DGTVRIWHSSTYRLES 265
Score = 65.3 bits (152), Expect = 1e-09
Identities = 49/248 (19%), Positives = 108/248 (43%), Gaps = 12/248 (4%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+ T + D + +++ R + F+ H + + + + ++ ++S D +++W
Sbjct: 72 VVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKK 131
Query: 96 GSTG-MFKAHSQTVRSVQFS-SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCA 153
S +F+ H+ V + + D ++ +AS D+ +K+W + GH V C
Sbjct: 132 WSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCI 191
Query: 154 RMSNDGS--IIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL---AWHPSGCYVAVAT 208
+ G + S +DD+ K+W+ + C+ T L+GH ++ ++HP + +
Sbjct: 192 DYYSGGDKPYLISGADDRLVKIWDYQNKTCVQT---LEGHAQNVSCASFHPELPIIITGS 248
Query: 209 SHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFT 268
G V+++ T+ L + E V VA + + +G + I+ L P +
Sbjct: 249 EDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSI-IVKLGREEPAMS 307
Query: 269 LSGHNGPV 276
+ NG +
Sbjct: 308 MDA-NGKI 314
>BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein complex,
subunit beta 2 (beta prime) protein.
Length = 906
Score = 90.2 bits (214), Expect = 3e-17
Identities = 66/252 (26%), Positives = 117/252 (46%), Gaps = 10/252 (3%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
+K++L + + ++ +P + + S + SV +W+ F+ D V F
Sbjct: 7 IKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFV 66
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+ ++ + + D +R++ MF+AHS +R + I+T+SDD ++KLW
Sbjct: 67 ARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLW 126
Query: 133 STHKHKFISS-FVGHTNWV-RCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
K S F GHT++V + D + AS S D++ K+W L S T L+G
Sbjct: 127 DWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFT---LEG 183
Query: 191 H--GLHLAWHPSG---CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSY 245
H G++ + SG Y+ VK++D + VQ H + V+ + HP
Sbjct: 184 HEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPI 243
Query: 246 ILTASKDGKMKI 257
I+T S+DG ++I
Sbjct: 244 IITGSEDGTVRI 255
Score = 81.4 bits (192), Expect = 1e-14
Identities = 45/162 (27%), Positives = 78/162 (48%), Gaps = 4/162 (2%)
Query: 18 KGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFS-SSG 75
+ H + I + +P I TSS D + LWD + S F+GH VM + +
Sbjct: 96 EAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDN 155
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK--IITASDDKVVKLWS 133
ASAS D+T+++W + + H + V + + S G K +I+ +DD++VK+W
Sbjct: 156 NQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWD 215
Query: 134 THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
+ + GH V CA + II + S+D + ++W+
Sbjct: 216 YQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWH 257
Score = 74.1 bits (174), Expect = 2e-12
Identities = 58/243 (23%), Positives = 109/243 (44%), Gaps = 5/243 (2%)
Query: 103 AHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSII 162
A S V+SV ++ + + V +W+ + +F VR A+ + +
Sbjct: 13 ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWV 72
Query: 163 ASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDI-RTH 221
+ +DD +++N ++ E +H ++ + +A HP+ ++ ++ +KL+D +
Sbjct: 73 VTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKW 132
Query: 222 NLVQYYSIHNEAVTQVAIHPS-GSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ Q + H V Q+ I+P + +AS D +K+ L P FTL GH VN ++
Sbjct: 133 SCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCID 192
Query: 281 FSPTGDT--FSSAGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENG 338
+ GD S DD+LV IW ++ E QN+ H I T +E+G
Sbjct: 193 YYSGGDKPYLISGADDRLVKIWDYQ-NKTCVQTLEGHAQNVSCASFHPELPIIITGSEDG 251
Query: 339 QIQ 341
++
Sbjct: 252 TVR 254
Score = 69.3 bits (162), Expect = 6e-11
Identities = 50/256 (19%), Positives = 110/256 (42%), Gaps = 4/256 (1%)
Query: 58 RFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDG 117
+ + V V + +M ++ + +V +W F+ VR+ +F +
Sbjct: 10 KLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARK 69
Query: 118 SKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
+ ++T +DD +++++ + + + F H++++RC + I + SDD KLW+ D
Sbjct: 70 NWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWD 129
Query: 178 SG-ECIHTYKDLKGHGLHLAWHPS-GCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT 235
C ++ + + + +P A A+ +K++ + + + H + V
Sbjct: 130 KKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVN 189
Query: 236 QVAIHPSGS--YILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGD 293
+ + G Y+++ + D +KI D + TL GH V+ +F P + +
Sbjct: 190 CIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSE 249
Query: 294 DKLVFIWKTNFTDLSS 309
D V IW ++ L S
Sbjct: 250 DGTVRIWHSSTYRLES 265
Score = 65.3 bits (152), Expect = 1e-09
Identities = 49/248 (19%), Positives = 108/248 (43%), Gaps = 12/248 (4%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVT 95
+ T + D + +++ R + F+ H + + + + ++ ++S D +++W
Sbjct: 72 VVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKK 131
Query: 96 GSTG-MFKAHSQTVRSVQFS-SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCA 153
S +F+ H+ V + + D ++ +AS D+ +K+W + GH V C
Sbjct: 132 WSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCI 191
Query: 154 RMSNDGS--IIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHL---AWHPSGCYVAVAT 208
+ G + S +DD+ K+W+ + C+ T L+GH ++ ++HP + +
Sbjct: 192 DYYSGGDKPYLISGADDRLVKIWDYQNKTCVQT---LEGHAQNVSCASFHPELPIIITGS 248
Query: 209 SHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFT 268
G V+++ T+ L + E V VA + + +G + I+ L P +
Sbjct: 249 EDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSI-IVKLGREEPAMS 307
Query: 269 LSGHNGPV 276
+ NG +
Sbjct: 308 MDA-NGKI 314
>AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens
cDNA FLJ16579 fis, clone TESTI2049956, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 472
Score = 89.4 bits (212), Expect = 5e-17
Identities = 47/166 (28%), Positives = 85/166 (51%), Gaps = 9/166 (5%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRF-QGHDEAVMDVTFSSSGKYM 78
H +IT+ ++P+ Q++A+ SLD + +WD+ + H A+ + F+ SG ++
Sbjct: 229 HTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFL 288
Query: 79 ASASRDKTVRIWVPTVTGS-------TGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
++S DK ++IW TG + + H +V S F+ D S +I+ D+ V +
Sbjct: 289 CTSSWDKNLKIW-NVHTGEFRNRGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAI 347
Query: 132 WSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLD 177
W + S GH +WV +SN+ I S S D++ +LWN++
Sbjct: 348 WDVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWNIE 393
Score = 85.8 bits (203), Expect = 7e-16
Identities = 72/303 (23%), Positives = 134/303 (44%), Gaps = 13/303 (4%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEA-VMDVTFSS 73
K L GH++A++ ++ +D ++ + S D +V LWD F+ +A V++ + +
Sbjct: 96 KILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITG 155
Query: 74 SGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQT-VRSVQFSSDGSKIITASD-DKVVKL 131
+ +AS DKTVR W TG ++K T + S +FS DG +++ D D + +
Sbjct: 156 DSSRVIAASYDKTVRAW-DLETGKL-LWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICI 213
Query: 132 WSTHKHKFISSFVGH-TNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKG 190
+S H T + D +AS S D+ K+W++ S + T
Sbjct: 214 MDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHS 273
Query: 191 HGL-HLAWHPSGCYVAVATSHGNVKLYDIRTHNL------VQYYSIHNEAVTQVAIHPSG 243
+ + + + SG ++ ++ N+K++++ T V H +V+
Sbjct: 274 NAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNRGACVTLMQGHEGSVSSCHFARDS 333
Query: 244 SYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
S++++ D + I D+ EG+ +L GHN V V S SA D+ + +W
Sbjct: 334 SFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWNIE 393
Query: 304 FTD 306
D
Sbjct: 394 EID 396
Score = 58.0 bits (134), Expect = 1e-07
Identities = 36/132 (27%), Positives = 62/132 (46%), Gaps = 6/132 (4%)
Query: 8 TPEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLR-GTMRS-----YRFQG 61
T + L K H NAI+ + + + TSS D ++ +W++ G R+ QG
Sbjct: 260 TSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNRGACVTLMQG 319
Query: 62 HDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKII 121
H+ +V F+ ++ S D+TV IW K H+ V V S++ I+
Sbjct: 320 HEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNNKKWIL 379
Query: 122 TASDDKVVKLWS 133
+AS D+ ++LW+
Sbjct: 380 SASKDRTMRLWN 391
>U63810-1|AAC24948.1| 339|Homo sapiens WD40 protein Ciao 1 protein.
Length = 339
Score = 88.6 bits (210), Expect = 9e-17
Identities = 55/199 (27%), Positives = 96/199 (48%), Gaps = 10/199 (5%)
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTG---STGMFKAHSQTVRSVQFSSDGSKIITASD 125
+ ++ +G +AS D+ +RIW + + + H +TVR V +S G+ + +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 126 DKVVKLWSTHKHKF--ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---E 180
D +W ++ F +++ GH N V+ + G+++A+CS DKS +W +D E
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYE 141
Query: 181 CIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI--HNEAVTQVA 238
C+ H+ WHPS +A A+ VKLY + V ++ H V +A
Sbjct: 142 CVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLA 201
Query: 239 IHPSGSYILTASKDGKMKI 257
PSG + + S D ++I
Sbjct: 202 FDPSGQRLASCSDDRTVRI 220
Score = 87.0 bits (206), Expect = 3e-16
Identities = 56/195 (28%), Positives = 94/195 (48%), Gaps = 10/195 (5%)
Query: 117 GSKIITASDDKVVKLWSTHKHKFISSFV---GHTNWVRCARMSNDGSIIASCSDDKSTKL 173
G+ + + D+ +++W T +I V GH VR S G+ +AS S D +T +
Sbjct: 28 GTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCI 87
Query: 174 W--NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI-- 229
W N D EC+ T + + +AW PSG +A + +V ++++ + + S+
Sbjct: 88 WKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLN 147
Query: 230 -HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIF--TLSGHNGPVNAVNFSPTGD 286
H + V V HPS + +AS D +K+ E + TL GH V ++ F P+G
Sbjct: 148 SHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQ 207
Query: 287 TFSSAGDDKLVFIWK 301
+S DD+ V IW+
Sbjct: 208 RLASCSDDRTVRIWR 222
Score = 73.3 bits (172), Expect = 4e-12
Identities = 42/170 (24%), Positives = 80/170 (47%), Gaps = 7/170 (4%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSY--RFQGHDEAVMDV 69
C +GH+ + + ++P +A++S D + +W +GH+ V V
Sbjct: 52 CKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSV 111
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGS---TGMFKAHSQTVRSVQFSSDGSKIITASDD 126
++ SG +A+ SRDK+V +W + +H+Q V+ V + + +AS D
Sbjct: 112 AWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYD 171
Query: 127 KVVKLWSTHKHKFI--SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
VKL+ + ++ ++ GH + V G +ASCSDD++ ++W
Sbjct: 172 DTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIW 221
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 28/192 (14%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLW--DLRGTMRSYRFQGHDEAVMDVTFSSS 74
L H + + ++P+ + +A++S D++V L+ + + +GH+ V + F S
Sbjct: 146 LNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPS 205
Query: 75 GKYMASASRDKTVRIW---VP------TVTGSTGMFKA-------HSQTVRSVQFSSDGS 118
G+ +AS S D+TVRIW +P +GS +K HS+T+ + +
Sbjct: 206 GQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTG 265
Query: 119 KIITASDDKVVKLWSTHKHK-------FISSFV--GHTNWVRCARMS-NDGSIIASCSDD 168
+ TA D ++++ + +++ + H+ V C + + ++ASCSDD
Sbjct: 266 ALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDD 325
Query: 169 KSTKLWNLDSGE 180
W E
Sbjct: 326 GEVAFWKYQRPE 337
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI---HNEAVTQVAIHPSGSYILTASK 251
LAW+P+G +A ++++ + + + H V +VA P G+Y+ +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 252 DGKMKILDLLEG--HPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTD 306
D I + + TL GH V +V ++P+G+ ++ DK V++W+ + D
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEED 138
>EF011618-1|ABK41108.1| 339|Homo sapiens CDW8/WDR39 protein.
Length = 339
Score = 88.6 bits (210), Expect = 9e-17
Identities = 55/199 (27%), Positives = 96/199 (48%), Gaps = 10/199 (5%)
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTG---STGMFKAHSQTVRSVQFSSDGSKIITASD 125
+ ++ +G +AS D+ +RIW + + + H +TVR V +S G+ + +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 126 DKVVKLWSTHKHKF--ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---E 180
D +W ++ F +++ GH N V+ + G+++A+CS DKS +W +D E
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYE 141
Query: 181 CIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI--HNEAVTQVA 238
C+ H+ WHPS +A A+ VKLY + V ++ H V +A
Sbjct: 142 CVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLA 201
Query: 239 IHPSGSYILTASKDGKMKI 257
PSG + + S D ++I
Sbjct: 202 FDPSGQRLASCSDDRTVRI 220
Score = 87.0 bits (206), Expect = 3e-16
Identities = 56/195 (28%), Positives = 94/195 (48%), Gaps = 10/195 (5%)
Query: 117 GSKIITASDDKVVKLWSTHKHKFISSFV---GHTNWVRCARMSNDGSIIASCSDDKSTKL 173
G+ + + D+ +++W T +I V GH VR S G+ +AS S D +T +
Sbjct: 28 GTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCI 87
Query: 174 W--NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI-- 229
W N D EC+ T + + +AW PSG +A + +V ++++ + + S+
Sbjct: 88 WKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLN 147
Query: 230 -HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIF--TLSGHNGPVNAVNFSPTGD 286
H + V V HPS + +AS D +K+ E + TL GH V ++ F P+G
Sbjct: 148 SHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQ 207
Query: 287 TFSSAGDDKLVFIWK 301
+S DD+ V IW+
Sbjct: 208 RLASCSDDRTVRIWR 222
Score = 73.3 bits (172), Expect = 4e-12
Identities = 42/170 (24%), Positives = 80/170 (47%), Gaps = 7/170 (4%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSY--RFQGHDEAVMDV 69
C +GH+ + + ++P +A++S D + +W +GH+ V V
Sbjct: 52 CKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSV 111
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGS---TGMFKAHSQTVRSVQFSSDGSKIITASDD 126
++ SG +A+ SRDK+V +W + +H+Q V+ V + + +AS D
Sbjct: 112 AWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYD 171
Query: 127 KVVKLWSTHKHKFI--SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
VKL+ + ++ ++ GH + V G +ASCSDD++ ++W
Sbjct: 172 DTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIW 221
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 28/192 (14%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLW--DLRGTMRSYRFQGHDEAVMDVTFSSS 74
L H + + ++P+ + +A++S D++V L+ + + +GH+ V + F S
Sbjct: 146 LNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPS 205
Query: 75 GKYMASASRDKTVRIW---VP------TVTGSTGMFKA-------HSQTVRSVQFSSDGS 118
G+ +AS S D+TVRIW +P +GS +K HS+T+ + +
Sbjct: 206 GQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTG 265
Query: 119 KIITASDDKVVKLWSTHKHK-------FISSFV--GHTNWVRCARMS-NDGSIIASCSDD 168
+ TA D ++++ + +++ + H+ V C + + ++ASCSDD
Sbjct: 266 ALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDD 325
Query: 169 KSTKLWNLDSGE 180
W E
Sbjct: 326 GEVAFWKYQRPE 337
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI---HNEAVTQVAIHPSGSYILTASK 251
LAW+P+G +A ++++ + + + H V +VA P G+Y+ +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 252 DGKMKILDLLEG--HPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTD 306
D I + + TL GH V +V ++P+G+ ++ DK V++W+ + D
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEED 138
>CR456802-1|CAG33083.1| 339|Homo sapiens CIAO1 protein.
Length = 339
Score = 88.6 bits (210), Expect = 9e-17
Identities = 55/199 (27%), Positives = 96/199 (48%), Gaps = 10/199 (5%)
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTG---STGMFKAHSQTVRSVQFSSDGSKIITASD 125
+ ++ +G +AS D+ +RIW + + + H +TVR V +S G+ + +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 126 DKVVKLWSTHKHKF--ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---E 180
D +W ++ F +++ GH N V+ + G+++A+CS DKS +W +D E
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYE 141
Query: 181 CIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI--HNEAVTQVA 238
C+ H+ WHPS +A A+ VKLY + V ++ H V +A
Sbjct: 142 CVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLA 201
Query: 239 IHPSGSYILTASKDGKMKI 257
PSG + + S D ++I
Sbjct: 202 FDPSGQRLASCSDDRTVRI 220
Score = 87.0 bits (206), Expect = 3e-16
Identities = 56/195 (28%), Positives = 94/195 (48%), Gaps = 10/195 (5%)
Query: 117 GSKIITASDDKVVKLWSTHKHKFISSFV---GHTNWVRCARMSNDGSIIASCSDDKSTKL 173
G+ + + D+ +++W T +I V GH VR S G+ +AS S D +T +
Sbjct: 28 GTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCI 87
Query: 174 W--NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI-- 229
W N D EC+ T + + +AW PSG +A + +V ++++ + + S+
Sbjct: 88 WKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLN 147
Query: 230 -HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIF--TLSGHNGPVNAVNFSPTGD 286
H + V V HPS + +AS D +K+ E + TL GH V ++ F P+G
Sbjct: 148 SHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQ 207
Query: 287 TFSSAGDDKLVFIWK 301
+S DD+ V IW+
Sbjct: 208 RLASCSDDRTVRIWR 222
Score = 73.3 bits (172), Expect = 4e-12
Identities = 42/170 (24%), Positives = 80/170 (47%), Gaps = 7/170 (4%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSY--RFQGHDEAVMDV 69
C +GH+ + + ++P +A++S D + +W +GH+ V V
Sbjct: 52 CKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSV 111
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGS---TGMFKAHSQTVRSVQFSSDGSKIITASDD 126
++ SG +A+ SRDK+V +W + +H+Q V+ V + + +AS D
Sbjct: 112 AWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYD 171
Query: 127 KVVKLWSTHKHKFI--SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
VKL+ + ++ ++ GH + V G +ASCSDD++ ++W
Sbjct: 172 DTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIW 221
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 28/192 (14%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLW--DLRGTMRSYRFQGHDEAVMDVTFSSS 74
L H + + ++P+ + +A++S D++V L+ + + +GH+ V + F S
Sbjct: 146 LNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPS 205
Query: 75 GKYMASASRDKTVRIW---VP------TVTGSTGMFKA-------HSQTVRSVQFSSDGS 118
G+ +AS S D+TVRIW +P +GS +K HS+T+ + +
Sbjct: 206 GQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTG 265
Query: 119 KIITASDDKVVKLWSTHKHK-------FISSFV--GHTNWVRCARMS-NDGSIIASCSDD 168
+ TA D ++++ + +++ + H+ V C + + ++ASCSDD
Sbjct: 266 ALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDD 325
Query: 169 KSTKLWNLDSGE 180
W E
Sbjct: 326 GEVAFWKYQRPE 337
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI---HNEAVTQVAIHPSGSYILTASK 251
LAW+P+G +A ++++ + + + H V +VA P G+Y+ +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 252 DGKMKILDLLEG--HPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTD 306
D I + + TL GH V +V ++P+G+ ++ DK V++W+ + D
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEED 138
>BC068499-1|AAH68499.1| 351|Homo sapiens THO complex 3 protein.
Length = 351
Score = 88.6 bits (210), Expect = 9e-17
Identities = 55/207 (26%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Query: 98 TGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFI--SSFVGHTNWVR--CA 153
T F AHS V SV +S DG ++ + S DK ++ K + + +++ GH + V C
Sbjct: 48 TREFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCW 107
Query: 154 RMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNV 213
SN + + S DK+ ++W++ + +CI T + KG +++ W P G +AV V
Sbjct: 108 HPSNP-DLFVTASGDKTIRIWDVRTTKCIATV-NTKGENINICWSPDGQTIAVGNKDDVV 165
Query: 214 KLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN 273
D +TH E V +++ + + + +G + IL E P+ +++ H
Sbjct: 166 TFIDAKTHRSKAEEQFKFE-VNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHP 224
Query: 274 GPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ F P G F++ D LV +W
Sbjct: 225 SNCICIKFDPMGKYFATGSADALVSLW 251
Score = 63.7 bits (148), Expect = 3e-09
Identities = 55/252 (21%), Positives = 99/252 (39%), Gaps = 5/252 (1%)
Query: 51 RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTG--STGMFKAHSQTV 108
RG ++ F H V V +S G+ +AS S DKT +++ ++ H +V
Sbjct: 43 RGHSKTREFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSV 102
Query: 109 RSVQFS-SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSD 167
+ + S+ +TAS DK +++W K I++ + S DG IA +
Sbjct: 103 DQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENINIC-WSPDGQTIAVGNK 161
Query: 168 DKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY 227
D + + + K ++W+ + +G + + VQ
Sbjct: 162 DDVVTFIDAKTHRS-KAEEQFKFEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSI 220
Query: 228 SIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDT 287
+ H + P G Y T S D + + D+ E + S + PV ++FS G
Sbjct: 221 NAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKM 280
Query: 288 FSSAGDDKLVFI 299
+SA +D + I
Sbjct: 281 LASASEDHFIDI 292
Score = 61.7 bits (143), Expect = 1e-08
Identities = 57/286 (19%), Positives = 124/286 (43%), Gaps = 10/286 (3%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDN--SVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
++ H + ++ ++ + +++A+ S D SV L + ++ ++GH ++V + +
Sbjct: 49 REFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWH 108
Query: 73 SSGKYM-ASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
S + +AS DKT+RIW T + + ++ +S DG I + D VV
Sbjct: 109 PSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENI-NICWSPDGQTIAVGNKDDVVTF 167
Query: 132 WS--THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
TH+ K F N + +ND ++ + + + + + + +
Sbjct: 168 IDAKTHRSKAEEQFKFEVNEIS---WNNDNNMFFLTNGNGCINILSYPELKPVQSINAHP 224
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
+ + + + P G Y A ++ V L+D+ V+ +S + V ++ G + +A
Sbjct: 225 SNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASA 284
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
S+D + I ++ G ++ + + P V + P + A DDK
Sbjct: 285 SEDHFIDIAEVETGDKLWEVQCES-PTFTVAWHPKRPLLAFACDDK 329
Score = 61.3 bits (142), Expect = 2e-08
Identities = 53/244 (21%), Positives = 108/244 (44%), Gaps = 14/244 (5%)
Query: 18 KGHKNAITALYYNPNDQQI-ATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
+GH +++ L ++P++ + T+S D ++ +WD+R T E + ++ +S G+
Sbjct: 96 RGHGDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENI-NICWSPDGQ 154
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQ---TVRSVQFSSDGSKIITASDDKVVKLWS 133
+A ++D V + T KA Q V + +++D + + + + + S
Sbjct: 155 TIAVGNKDDVVTF----IDAKTHRSKAEEQFKFEVNEISWNNDNNMFFLTNGNGCINILS 210
Query: 134 THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGL 193
+ K + S H + C + G A+ S D LW++D C+ + L
Sbjct: 211 YPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVR 270
Query: 194 HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT-QVAIHPSGSYILTA--S 250
L++ G +A A+ + + ++ T + + + + E+ T VA HP + A
Sbjct: 271 TLSFSHDGKMLASASEDHFIDIAEVETGD--KLWEVQCESPTFTVAWHPKRPLLAFACDD 328
Query: 251 KDGK 254
KDGK
Sbjct: 329 KDGK 332
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/206 (21%), Positives = 86/206 (41%), Gaps = 4/206 (1%)
Query: 29 YNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
++P+ Q IA + D+ V D + T RS + V ++++++ + + +
Sbjct: 149 WSPDGQTIAVGNKDDVVTFIDAK-THRSKAEEQFKFEVNEISWNNDNNMFFLTNGNGCIN 207
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
I AH ++F G T S D +V LW + + F +
Sbjct: 208 ILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCF-SRLD 266
Query: 149 W-VRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVA 207
W VR S+DG ++AS S+D + +++G+ + + + +AWHP +A A
Sbjct: 267 WPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQ-CESPTFTVAWHPKRPLLAFA 325
Query: 208 TSHGNVKLYDIRTHNLVQYYSIHNEA 233
+ K R V+ + + N++
Sbjct: 326 CDDKDGKYDSSREAGTVKLFGLPNDS 351
Score = 41.1 bits (92), Expect = 0.018
Identities = 25/81 (30%), Positives = 38/81 (46%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
PE + + H + + ++P + AT S D V LWD+ + F D V
Sbjct: 212 PELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRT 271
Query: 69 VTFSSSGKYMASASRDKTVRI 89
++FS GK +ASAS D + I
Sbjct: 272 LSFSHDGKMLASASEDHFIDI 292
>BC066325-1|AAH66325.1| 327|Homo sapiens THOC3 protein protein.
Length = 327
Score = 88.6 bits (210), Expect = 9e-17
Identities = 55/207 (26%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Query: 98 TGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFI--SSFVGHTNWVR--CA 153
T F AHS V SV +S DG ++ + S DK ++ K + + +++ GH + V C
Sbjct: 48 TREFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCW 107
Query: 154 RMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNV 213
SN + + S DK+ ++W++ + +CI T + KG +++ W P G +AV V
Sbjct: 108 HPSNP-DLFVTASGDKTIRIWDVRTTKCIATV-NTKGENINICWSPDGQTIAVGNKDDVV 165
Query: 214 KLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN 273
D +TH E V +++ + + + +G + IL E P+ +++ H
Sbjct: 166 TFIDAKTHRSKAEEQFKFE-VNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHP 224
Query: 274 GPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ F P G F++ D LV +W
Sbjct: 225 SNCICIKFDPMGKYFATGSADALVSLW 251
Score = 63.7 bits (148), Expect = 3e-09
Identities = 55/252 (21%), Positives = 99/252 (39%), Gaps = 5/252 (1%)
Query: 51 RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTG--STGMFKAHSQTV 108
RG ++ F H V V +S G+ +AS S DKT +++ ++ H +V
Sbjct: 43 RGHSKTREFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSV 102
Query: 109 RSVQFS-SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSD 167
+ + S+ +TAS DK +++W K I++ + S DG IA +
Sbjct: 103 DQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENINIC-WSPDGQTIAVGNK 161
Query: 168 DKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY 227
D + + + K ++W+ + +G + + VQ
Sbjct: 162 DDVVTFIDAKTHRS-KAEEQFKFEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSI 220
Query: 228 SIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDT 287
+ H + P G Y T S D + + D+ E + S + PV ++FS G
Sbjct: 221 NAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKM 280
Query: 288 FSSAGDDKLVFI 299
+SA +D + I
Sbjct: 281 LASASEDHFIDI 292
Score = 62.1 bits (144), Expect = 9e-09
Identities = 46/221 (20%), Positives = 98/221 (44%), Gaps = 9/221 (4%)
Query: 18 KGHKNAITALYYNPNDQQI-ATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
+GH +++ L ++P++ + T+S D ++ +WD+R T E + ++ +S G+
Sbjct: 96 RGHGDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENI-NICWSPDGQ 154
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQ---TVRSVQFSSDGSKIITASDDKVVKLWS 133
+A ++D V + T KA Q V + +++D + + + + + S
Sbjct: 155 TIAVGNKDDVVTF----IDAKTHRSKAEEQFKFEVNEISWNNDNNMFFLTNGNGCINILS 210
Query: 134 THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGL 193
+ K + S H + C + G A+ S D LW++D C+ + L
Sbjct: 211 YPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVR 270
Query: 194 HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV 234
L++ G +A A+ + + ++ T N ++ Y + AV
Sbjct: 271 TLSFSHDGKMLASASEDHFIDIAEVETGNFMRIYRLSPLAV 311
Score = 56.8 bits (131), Expect = 3e-07
Identities = 50/255 (19%), Positives = 112/255 (43%), Gaps = 9/255 (3%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDN--SVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
++ H + ++ ++ + +++A+ S D SV L + ++ ++GH ++V + +
Sbjct: 49 REFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWH 108
Query: 73 SSGKYM-ASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
S + +AS DKT+RIW T + + ++ +S DG I + D VV
Sbjct: 109 PSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENI-NICWSPDGQTIAVGNKDDVVTF 167
Query: 132 WS--THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
TH+ K F N + +ND ++ + + + + + + +
Sbjct: 168 IDAKTHRSKAEEQFKFEVNEIS---WNNDNNMFFLTNGNGCINILSYPELKPVQSINAHP 224
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
+ + + + P G Y A ++ V L+D+ V+ +S + V ++ G + +A
Sbjct: 225 SNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASA 284
Query: 250 SKDGKMKILDLLEGH 264
S+D + I ++ G+
Sbjct: 285 SEDHFIDIAEVETGN 299
Score = 41.1 bits (92), Expect = 0.018
Identities = 25/81 (30%), Positives = 38/81 (46%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
PE + + H + + ++P + AT S D V LWD+ + F D V
Sbjct: 212 PELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRT 271
Query: 69 VTFSSSGKYMASASRDKTVRI 89
++FS GK +ASAS D + I
Sbjct: 272 LSFSHDGKMLASASEDHFIDI 292
>BC032812-1|AAH32812.1| 339|Homo sapiens cytosolic iron-sulfur
protein assembly 1 homolog (S. cerevisiae) protein.
Length = 339
Score = 88.6 bits (210), Expect = 9e-17
Identities = 55/199 (27%), Positives = 96/199 (48%), Gaps = 10/199 (5%)
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTG---STGMFKAHSQTVRSVQFSSDGSKIITASD 125
+ ++ +G +AS D+ +RIW + + + H +TVR V +S G+ + +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 126 DKVVKLWSTHKHKF--ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---E 180
D +W ++ F +++ GH N V+ + G+++A+CS DKS +W +D E
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYE 141
Query: 181 CIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI--HNEAVTQVA 238
C+ H+ WHPS +A A+ VKLY + V ++ H V +A
Sbjct: 142 CVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLA 201
Query: 239 IHPSGSYILTASKDGKMKI 257
PSG + + S D ++I
Sbjct: 202 FDPSGQRLASCSDDRTVRI 220
Score = 87.0 bits (206), Expect = 3e-16
Identities = 56/195 (28%), Positives = 94/195 (48%), Gaps = 10/195 (5%)
Query: 117 GSKIITASDDKVVKLWSTHKHKFISSFV---GHTNWVRCARMSNDGSIIASCSDDKSTKL 173
G+ + + D+ +++W T +I V GH VR S G+ +AS S D +T +
Sbjct: 28 GTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCI 87
Query: 174 W--NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI-- 229
W N D EC+ T + + +AW PSG +A + +V ++++ + + S+
Sbjct: 88 WKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLN 147
Query: 230 -HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIF--TLSGHNGPVNAVNFSPTGD 286
H + V V HPS + +AS D +K+ E + TL GH V ++ F P+G
Sbjct: 148 SHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQ 207
Query: 287 TFSSAGDDKLVFIWK 301
+S DD+ V IW+
Sbjct: 208 RLASCSDDRTVRIWR 222
Score = 73.3 bits (172), Expect = 4e-12
Identities = 42/170 (24%), Positives = 80/170 (47%), Gaps = 7/170 (4%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSY--RFQGHDEAVMDV 69
C +GH+ + + ++P +A++S D + +W +GH+ V V
Sbjct: 52 CKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSV 111
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGS---TGMFKAHSQTVRSVQFSSDGSKIITASDD 126
++ SG +A+ SRDK+V +W + +H+Q V+ V + + +AS D
Sbjct: 112 AWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYD 171
Query: 127 KVVKLWSTHKHKFI--SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
VKL+ + ++ ++ GH + V G +ASCSDD++ ++W
Sbjct: 172 DTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIW 221
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 28/192 (14%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLW--DLRGTMRSYRFQGHDEAVMDVTFSSS 74
L H + + ++P+ + +A++S D++V L+ + + +GH+ V + F S
Sbjct: 146 LNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPS 205
Query: 75 GKYMASASRDKTVRIW---VP------TVTGSTGMFKA-------HSQTVRSVQFSSDGS 118
G+ +AS S D+TVRIW +P +GS +K HS+T+ + +
Sbjct: 206 GQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTG 265
Query: 119 KIITASDDKVVKLWSTHKHK-------FISSFV--GHTNWVRCARMS-NDGSIIASCSDD 168
+ TA D ++++ + +++ + H+ V C + + ++ASCSDD
Sbjct: 266 ALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDD 325
Query: 169 KSTKLWNLDSGE 180
W E
Sbjct: 326 GEVAFWKYQRPE 337
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI---HNEAVTQVAIHPSGSYILTASK 251
LAW+P+G +A ++++ + + + H V +VA P G+Y+ +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 252 DGKMKILDLLEG--HPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTD 306
D I + + TL GH V +V ++P+G+ ++ DK V++W+ + D
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEED 138
>BC006849-1|AAH06849.1| 351|Homo sapiens THO complex 3 protein.
Length = 351
Score = 88.6 bits (210), Expect = 9e-17
Identities = 55/207 (26%), Positives = 98/207 (47%), Gaps = 7/207 (3%)
Query: 98 TGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFI--SSFVGHTNWVR--CA 153
T F AHS V SV +S DG ++ + S DK ++ K + + +++ GH + V C
Sbjct: 48 TREFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCW 107
Query: 154 RMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNV 213
SN + + S DK+ ++W++ + +CI T + KG +++ W P G +AV V
Sbjct: 108 HPSNP-DLFVTASGDKTIRIWDVRTTKCIATV-NTKGENINICWSPDGQTIAVGNKDDVV 165
Query: 214 KLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHN 273
D +TH E V +++ + + + +G + IL E P+ +++ H
Sbjct: 166 TFIDAKTHRSKAEEQFKFE-VNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHP 224
Query: 274 GPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ F P G F++ D LV +W
Sbjct: 225 SNCICIKFDPMGKYFATGSADALVSLW 251
Score = 63.7 bits (148), Expect = 3e-09
Identities = 55/252 (21%), Positives = 99/252 (39%), Gaps = 5/252 (1%)
Query: 51 RGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTG--STGMFKAHSQTV 108
RG ++ F H V V +S G+ +AS S DKT +++ ++ H +V
Sbjct: 43 RGHSKTREFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSV 102
Query: 109 RSVQFS-SDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSD 167
+ + S+ +TAS DK +++W K I++ + S DG IA +
Sbjct: 103 DQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENINIC-WSPDGQTIAVGNK 161
Query: 168 DKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY 227
D + + + K ++W+ + +G + + VQ
Sbjct: 162 DDVVTFIDAKTHRS-KAEEQFKFEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSI 220
Query: 228 SIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDT 287
+ H + P G Y T S D + + D+ E + S + PV ++FS G
Sbjct: 221 NAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKM 280
Query: 288 FSSAGDDKLVFI 299
+SA +D + I
Sbjct: 281 LASASEDHFIDI 292
Score = 61.7 bits (143), Expect = 1e-08
Identities = 57/286 (19%), Positives = 124/286 (43%), Gaps = 10/286 (3%)
Query: 15 KQLKGHKNAITALYYNPNDQQIATSSLDN--SVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
++ H + ++ ++ + +++A+ S D SV L + ++ ++GH ++V + +
Sbjct: 49 REFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWH 108
Query: 73 SSGKYM-ASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKL 131
S + +AS DKT+RIW T + + ++ +S DG I + D VV
Sbjct: 109 PSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENI-NICWSPDGQTIAVGNKDDVVTF 167
Query: 132 WS--THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLK 189
TH+ K F N + +ND ++ + + + + + + +
Sbjct: 168 IDAKTHRSKAEEQFKFEVNEIS---WNNDNNMFFLTNGNGCINILSYPELKPVQSINAHP 224
Query: 190 GHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTA 249
+ + + + P G Y A ++ V L+D+ V+ +S + V ++ G + +A
Sbjct: 225 SNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASA 284
Query: 250 SKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDK 295
S+D + I ++ G ++ + + P V + P + A DDK
Sbjct: 285 SEDHFIDIAEVETGDKLWEVQCES-PTFTVAWHPKRPLLAFACDDK 329
Score = 61.3 bits (142), Expect = 2e-08
Identities = 53/244 (21%), Positives = 108/244 (44%), Gaps = 14/244 (5%)
Query: 18 KGHKNAITALYYNPNDQQI-ATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
+GH +++ L ++P++ + T+S D ++ +WD+R T E + ++ +S G+
Sbjct: 96 RGHGDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENI-NICWSPDGQ 154
Query: 77 YMASASRDKTVRIWVPTVTGSTGMFKAHSQ---TVRSVQFSSDGSKIITASDDKVVKLWS 133
+A ++D V + T KA Q V + +++D + + + + + S
Sbjct: 155 TIAVGNKDDVVTF----IDAKTHRSKAEEQFKFEVNEISWNNDNNMFFLTNGNGCINILS 210
Query: 134 THKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGL 193
+ K + S H + C + G A+ S D LW++D C+ + L
Sbjct: 211 YPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVR 270
Query: 194 HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVT-QVAIHPSGSYILTA--S 250
L++ G +A A+ + + ++ T + + + + E+ T VA HP + A
Sbjct: 271 TLSFSHDGKMLASASEDHFIDIAEVETGD--KLWEVQCESPTFTVAWHPKRPLLAFACDD 328
Query: 251 KDGK 254
KDGK
Sbjct: 329 KDGK 332
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/206 (21%), Positives = 86/206 (41%), Gaps = 4/206 (1%)
Query: 29 YNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVR 88
++P+ Q IA + D+ V D + T RS + V ++++++ + + +
Sbjct: 149 WSPDGQTIAVGNKDDVVTFIDAK-THRSKAEEQFKFEVNEISWNNDNNMFFLTNGNGCIN 207
Query: 89 IWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTN 148
I AH ++F G T S D +V LW + + F +
Sbjct: 208 ILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCF-SRLD 266
Query: 149 W-VRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVA 207
W VR S+DG ++AS S+D + +++G+ + + + +AWHP +A A
Sbjct: 267 WPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQ-CESPTFTVAWHPKRPLLAFA 325
Query: 208 TSHGNVKLYDIRTHNLVQYYSIHNEA 233
+ K R V+ + + N++
Sbjct: 326 CDDKDGKYDSSREAGTVKLFGLPNDS 351
Score = 41.1 bits (92), Expect = 0.018
Identities = 25/81 (30%), Positives = 38/81 (46%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
PE + + H + + ++P + AT S D V LWD+ + F D V
Sbjct: 212 PELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRT 271
Query: 69 VTFSSSGKYMASASRDKTVRI 89
++FS GK +ASAS D + I
Sbjct: 272 LSFSHDGKMLASASEDHFIDI 292
>BC001395-1|AAH01395.1| 339|Homo sapiens cytosolic iron-sulfur
protein assembly 1 homolog (S. cerevisiae) protein.
Length = 339
Score = 88.6 bits (210), Expect = 9e-17
Identities = 55/199 (27%), Positives = 96/199 (48%), Gaps = 10/199 (5%)
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTG---STGMFKAHSQTVRSVQFSSDGSKIITASD 125
+ ++ +G +AS D+ +RIW + + + H +TVR V +S G+ + +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 126 DKVVKLWSTHKHKF--ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---E 180
D +W ++ F +++ GH N V+ + G+++A+CS DKS +W +D E
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYE 141
Query: 181 CIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI--HNEAVTQVA 238
C+ H+ WHPS +A A+ VKLY + V ++ H V +A
Sbjct: 142 CVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLA 201
Query: 239 IHPSGSYILTASKDGKMKI 257
PSG + + S D ++I
Sbjct: 202 FDPSGQRLASCSDDRTVRI 220
Score = 87.0 bits (206), Expect = 3e-16
Identities = 56/195 (28%), Positives = 94/195 (48%), Gaps = 10/195 (5%)
Query: 117 GSKIITASDDKVVKLWSTHKHKFISSFV---GHTNWVRCARMSNDGSIIASCSDDKSTKL 173
G+ + + D+ +++W T +I V GH VR S G+ +AS S D +T +
Sbjct: 28 GTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCI 87
Query: 174 W--NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI-- 229
W N D EC+ T + + +AW PSG +A + +V ++++ + + S+
Sbjct: 88 WKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLN 147
Query: 230 -HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIF--TLSGHNGPVNAVNFSPTGD 286
H + V V HPS + +AS D +K+ E + TL GH V ++ F P+G
Sbjct: 148 SHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQ 207
Query: 287 TFSSAGDDKLVFIWK 301
+S DD+ V IW+
Sbjct: 208 RLASCSDDRTVRIWR 222
Score = 73.3 bits (172), Expect = 4e-12
Identities = 42/170 (24%), Positives = 80/170 (47%), Gaps = 7/170 (4%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSY--RFQGHDEAVMDV 69
C +GH+ + + ++P +A++S D + +W +GH+ V V
Sbjct: 52 CKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSV 111
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGS---TGMFKAHSQTVRSVQFSSDGSKIITASDD 126
++ SG +A+ SRDK+V +W + +H+Q V+ V + + +AS D
Sbjct: 112 AWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYD 171
Query: 127 KVVKLWSTHKHKFI--SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
VKL+ + ++ ++ GH + V G +ASCSDD++ ++W
Sbjct: 172 DTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIW 221
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 28/192 (14%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLW--DLRGTMRSYRFQGHDEAVMDVTFSSS 74
L H + + ++P+ + +A++S D++V L+ + + +GH+ V + F S
Sbjct: 146 LNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPS 205
Query: 75 GKYMASASRDKTVRIW---VP------TVTGSTGMFKA-------HSQTVRSVQFSSDGS 118
G+ +AS S D+TVRIW +P +GS +K HS+T+ + +
Sbjct: 206 GQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTG 265
Query: 119 KIITASDDKVVKLWSTHKHK-------FISSFV--GHTNWVRCARMS-NDGSIIASCSDD 168
+ TA D ++++ + +++ + H+ V C + + ++ASCSDD
Sbjct: 266 ALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDD 325
Query: 169 KSTKLWNLDSGE 180
W E
Sbjct: 326 GEVAFWKYQRPE 337
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI---HNEAVTQVAIHPSGSYILTASK 251
LAW+P+G +A ++++ + + + H V +VA P G+Y+ +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 252 DGKMKILDLLEG--HPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTD 306
D I + + TL GH V +V ++P+G+ ++ DK V++W+ + D
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEED 138
>AK223257-1|BAD96977.1| 339|Homo sapiens WD40 protein Ciao1 variant
protein.
Length = 339
Score = 88.6 bits (210), Expect = 9e-17
Identities = 55/199 (27%), Positives = 96/199 (48%), Gaps = 10/199 (5%)
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTG---STGMFKAHSQTVRSVQFSSDGSKIITASD 125
+ ++ +G +AS D+ +RIW + + + H +TVR V +S G+ + +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 126 DKVVKLWSTHKHKF--ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---E 180
D +W ++ F +++ GH N V+ + G+++A+CS DKS +W +D E
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYE 141
Query: 181 CIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI--HNEAVTQVA 238
C+ H+ WHPS +A A+ VKLY + V ++ H V +A
Sbjct: 142 CVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLA 201
Query: 239 IHPSGSYILTASKDGKMKI 257
PSG + + S D ++I
Sbjct: 202 FDPSGQRLASCSDDRTVRI 220
Score = 87.0 bits (206), Expect = 3e-16
Identities = 56/195 (28%), Positives = 94/195 (48%), Gaps = 10/195 (5%)
Query: 117 GSKIITASDDKVVKLWSTHKHKFISSFV---GHTNWVRCARMSNDGSIIASCSDDKSTKL 173
G+ + + D+ +++W T +I V GH VR S G+ +AS S D +T +
Sbjct: 28 GTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCI 87
Query: 174 W--NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI-- 229
W N D EC+ T + + +AW PSG +A + +V ++++ + + S+
Sbjct: 88 WKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLN 147
Query: 230 -HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIF--TLSGHNGPVNAVNFSPTGD 286
H + V V HPS + +AS D +K+ E + TL GH V ++ F P+G
Sbjct: 148 SHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQ 207
Query: 287 TFSSAGDDKLVFIWK 301
+S DD+ V IW+
Sbjct: 208 RLASCSDDRTVRIWR 222
Score = 73.3 bits (172), Expect = 4e-12
Identities = 42/170 (24%), Positives = 80/170 (47%), Gaps = 7/170 (4%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSY--RFQGHDEAVMDV 69
C +GH+ + + ++P +A++S D + +W +GH+ V V
Sbjct: 52 CKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSV 111
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGS---TGMFKAHSQTVRSVQFSSDGSKIITASDD 126
++ SG +A+ SRDK+V +W + +H+Q V+ V + + +AS D
Sbjct: 112 AWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYD 171
Query: 127 KVVKLWSTHKHKFI--SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
VKL+ + ++ ++ GH + V G +ASCSDD++ ++W
Sbjct: 172 DTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIW 221
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 28/192 (14%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLW--DLRGTMRSYRFQGHDEAVMDVTFSSS 74
L H + + ++P+ + +A++S D++V L+ + + +GH+ V + F S
Sbjct: 146 LNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPS 205
Query: 75 GKYMASASRDKTVRIW---VP------TVTGSTGMFKA-------HSQTVRSVQFSSDGS 118
G+ +AS S D+TVRIW +P +GS +K HS+T+ + +
Sbjct: 206 GQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKGICTLSGFHSRTIYDIAWCQLTG 265
Query: 119 KIITASDDKVVKLWSTHKHK-------FISSFV--GHTNWVRCARMS-NDGSIIASCSDD 168
+ TA D ++++ + +++ + H+ V C + + ++ASCSDD
Sbjct: 266 ALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDD 325
Query: 169 KSTKLWNLDSGE 180
W E
Sbjct: 326 GEVAFWKYQRPE 337
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI---HNEAVTQVAIHPSGSYILTASK 251
LAW+P+G +A ++++ + + + H V +VA P G+Y+ +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 252 DGKMKILDLLEG--HPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTD 306
D I + + TL GH V +V ++P+G+ ++ DK V++W+ + D
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEED 138
>AC004020-1|AAC23493.1| 339|Homo sapiens Unknown gene product
protein.
Length = 339
Score = 88.6 bits (210), Expect = 9e-17
Identities = 55/199 (27%), Positives = 96/199 (48%), Gaps = 10/199 (5%)
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTG---STGMFKAHSQTVRSVQFSSDGSKIITASD 125
+ ++ +G +AS D+ +RIW + + + H +TVR V +S G+ + +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 126 DKVVKLWSTHKHKF--ISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG---E 180
D +W ++ F +++ GH N V+ + G+++A+CS DKS +W +D E
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYE 141
Query: 181 CIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI--HNEAVTQVA 238
C+ H+ WHPS +A A+ VKLY + V ++ H V +A
Sbjct: 142 CVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLA 201
Query: 239 IHPSGSYILTASKDGKMKI 257
PSG + + S D ++I
Sbjct: 202 FDPSGQRLASCSDDRTVRI 220
Score = 87.0 bits (206), Expect = 3e-16
Identities = 56/195 (28%), Positives = 94/195 (48%), Gaps = 10/195 (5%)
Query: 117 GSKIITASDDKVVKLWSTHKHKFISSFV---GHTNWVRCARMSNDGSIIASCSDDKSTKL 173
G+ + + D+ +++W T +I V GH VR S G+ +AS S D +T +
Sbjct: 28 GTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCI 87
Query: 174 W--NLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI-- 229
W N D EC+ T + + +AW PSG +A + +V ++++ + + S+
Sbjct: 88 WKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLN 147
Query: 230 -HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIF--TLSGHNGPVNAVNFSPTGD 286
H + V V HPS + +AS D +K+ E + TL GH V ++ F P+G
Sbjct: 148 SHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQ 207
Query: 287 TFSSAGDDKLVFIWK 301
+S DD+ V IW+
Sbjct: 208 RLASCSDDRTVRIWR 222
Score = 73.3 bits (172), Expect = 4e-12
Identities = 42/170 (24%), Positives = 80/170 (47%), Gaps = 7/170 (4%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSY--RFQGHDEAVMDV 69
C +GH+ + + ++P +A++S D + +W +GH+ V V
Sbjct: 52 CKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSV 111
Query: 70 TFSSSGKYMASASRDKTVRIWVPTVTGS---TGMFKAHSQTVRSVQFSSDGSKIITASDD 126
++ SG +A+ SRDK+V +W + +H+Q V+ V + + +AS D
Sbjct: 112 AWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYD 171
Query: 127 KVVKLWSTHKHKFI--SSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
VKL+ + ++ ++ GH + V G +ASCSDD++ ++W
Sbjct: 172 DTVKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIW 221
Score = 51.6 bits (118), Expect = 1e-05
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 28/192 (14%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLW--DLRGTMRSYRFQGHDEAVMDVTFSSS 74
L H + + ++P+ + +A++S D++V L+ + + +GH+ V + F S
Sbjct: 146 LNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDPS 205
Query: 75 GKYMASASRDKTVRIW---VP------TVTGSTGMFKA-------HSQTVRSVQFSSDGS 118
G+ +AS S D+TVRIW +P +GS +K HS+T+ + +
Sbjct: 206 GQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHSRTIYDIAWCQLTG 265
Query: 119 KIITASDDKVVKLWSTHKHK-------FISSFV--GHTNWVRCARMS-NDGSIIASCSDD 168
+ TA D ++++ + +++ + H+ V C + + ++ASCSDD
Sbjct: 266 ALATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDD 325
Query: 169 KSTKLWNLDSGE 180
W E
Sbjct: 326 GEVAFWKYQRPE 337
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI---HNEAVTQVAIHPSGSYILTASK 251
LAW+P+G +A ++++ + + + H V +VA P G+Y+ +AS
Sbjct: 22 LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81
Query: 252 DGKMKILDLLEG--HPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTNFTD 306
D I + + TL GH V +V ++P+G+ ++ DK V++W+ + D
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEED 138
>BC029520-1|AAH29520.1| 384|Homo sapiens WDSUB1 protein protein.
Length = 384
Score = 88.2 bits (209), Expect = 1e-16
Identities = 76/298 (25%), Positives = 138/298 (46%), Gaps = 21/298 (7%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFI--SSFVGHTNWVRCARMSNDGSI 161
H V FS S + T S DK ++L+S + S HT V C S G I
Sbjct: 11 HGDDVNCCAFSF--SLLATCSLDKTIRLYSLRDFTELPHSPLKFHTYAVHCCCFSPSGHI 68
Query: 162 IASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLA-WHPSGCYVAVATSHGNVKLYDIRT 220
+ASCS D +T LWN ++G+ + + G + + + P +A + G V L++ ++
Sbjct: 69 LASCSTDGTTVLWNTENGQMLAVMEQPSGSPVRVCQFSPDSTCLASGAADGTVVLWNAQS 128
Query: 221 HNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ L + S+ + ++ A P+GS+ +T S G + + D + + + H+ + +
Sbjct: 129 YKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWD-DKMRCLHSEKAHDLGITCCD 187
Query: 281 FS--PTGD--------TFSSAGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEG 330
FS P D +S G D V IW +FTD+ + E++ + +EE
Sbjct: 188 FSSQPVSDGEQGLQFFRLASCGQDCQVKIWIVSFTDILARRTEHQLKQF---TEDWSEED 244
Query: 331 IDTITENGQIQD-VNILSKKALD-YDLRDISEGSLPEDFVKDPSKLESPVVVQIQKIR 386
+ T ++D V I +D +L ++++ SL +D + L S V+ +I+++R
Sbjct: 245 VSTWLCAQDLKDLVGIFKMNNIDGKELLNLTKESLADDLKIESLGLRSKVLRKIEELR 302
Score = 48.4 bits (110), Expect = 1e-04
Identities = 42/169 (24%), Positives = 68/169 (40%), Gaps = 12/169 (7%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-RGTMRSYRFQGHDEAVMDVTFSSSG 75
LK H A+ ++P+ +A+ S D + +LW+ G M + Q V FS
Sbjct: 50 LKFHTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLAVMEQPSGSPVRVCQFSPDS 109
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
+AS + D TV +W ++ + FS +GS +T S + +W
Sbjct: 110 TCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWD-D 168
Query: 136 KHKFISSFVGHTNWVRCARMS----NDGS------IIASCSDDKSTKLW 174
K + + S H + C S +DG +ASC D K+W
Sbjct: 169 KMRCLHSEKAHDLGITCCDFSSQPVSDGEQGLQFFRLASCGQDCQVKIW 217
>AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3
protein.
Length = 943
Score = 88.2 bits (209), Expect = 1e-16
Identities = 62/244 (25%), Positives = 111/244 (45%), Gaps = 17/244 (6%)
Query: 28 YYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTV 87
++ P D+Q+ + + L+DL HD A+ ++ S + + DK+V
Sbjct: 461 FFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSV 520
Query: 88 RIW-VPTVTGSTGMFKAHS-QTVRSVQFSSD--------GSKIITASD-DKVVKLWSTHK 136
+ W V K S + R++Q D K++ S D VK++
Sbjct: 521 KFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDT 580
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG---L 193
KF S GH V C +S+DG++IA+ S D++ K+W LD G+C +K L H +
Sbjct: 581 LKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDC---HKSLFAHDDSVM 637
Query: 194 HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDG 253
+L + P A +K +D +Q H++ + +A+ PSG Y++++S D
Sbjct: 638 YLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDK 697
Query: 254 KMKI 257
+++
Sbjct: 698 SLRL 701
Score = 76.2 bits (179), Expect = 5e-13
Identities = 43/151 (28%), Positives = 67/151 (44%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+ + Y+PN + +A S LD +V ++ + GH V+ + S G +A+ S
Sbjct: 552 VLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSA 611
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
D+ V+IW AH +V +QF TA D +K W K + I +
Sbjct: 612 DRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTL 671
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
GH + C +S G + S S DKS +LW
Sbjct: 672 EGHHQEIWCLAVSPSGDYVVSSSHDKSLRLW 702
Score = 70.9 bits (166), Expect = 2e-11
Identities = 71/331 (21%), Positives = 142/331 (42%), Gaps = 23/331 (6%)
Query: 2 MEDKVTTPEPCLKKQLK--GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRF 59
+ + TP+P ++ GH++ + L ++ ++ + +++ D S+ +W+ R T++ R
Sbjct: 394 LNPSLPTPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAAD-SIKIWN-RSTLQCIRT 451
Query: 60 QGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
+ A+ F + + ++ ++++ AH + S+ S D
Sbjct: 452 MTCEYALCSF-FVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRG 510
Query: 120 IITASDDKVVKLW---------STHKHKFISSF--VGHTNWVRCARMSNDGSIIASCSDD 168
+T DK VK W ST K + + V C S + ++A D
Sbjct: 511 FVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLD 570
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHP---SGCYVAVATSHGNVKLYDIRTHNLVQ 225
+ K++ +D+ + + L GH L + G +A ++ NVK++ + + +
Sbjct: 571 CTVKIFYVDT---LKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHK 627
Query: 226 YYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTG 285
H+++V + P TA KD K+K D + I TL GH+ + + SP+G
Sbjct: 628 SLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSG 687
Query: 286 DTFSSAGDDKLVFIW-KTNFTDLSSESKENE 315
D S+ DK + +W +T + E +E E
Sbjct: 688 DYVVSSSHDKSLRLWERTREPLILEEEREME 718
Score = 66.9 bits (156), Expect = 3e-10
Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L+G K +T L +P+ +A D S+ ++ L + F GH A+ + + G
Sbjct: 61 LQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGG 120
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF--KAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
+AS S+D + +W V +G++ K H + F + + ++T+ D +VK W
Sbjct: 121 RLASGSKDTDIIVW--DVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDL 178
Query: 135 HKHKFISSFVGHTNWV-RCARMSNDGSIIASCSDDKSTKLWNL 176
+ VGH V +S + +I SD + ++W++
Sbjct: 179 DTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSE-LRVWDI 220
Score = 56.8 bits (131), Expect = 3e-07
Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 3/147 (2%)
Query: 45 VLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH 104
V +WDLR + QG + V + S G ++A D ++RI+ F H
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGH 106
Query: 105 SQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIAS 164
+ ++++ G ++ + S D + +W + GH + + A + +++ +
Sbjct: 107 KAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVT 166
Query: 165 CSDDKSTKLWNLDSGECIHTYKDLKGH 191
D K W+LD+ C +K + GH
Sbjct: 167 SGKDTMVKWWDLDTQHC---FKTMVGH 190
Score = 52.4 bits (120), Expect = 7e-06
Identities = 29/128 (22%), Positives = 58/128 (45%)
Query: 173 LWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE 232
+W+L GE I + LK L P G ++AV G+++++ + + ++ H
Sbjct: 49 IWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKA 108
Query: 233 AVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
A+T + G + + SKD + + D++ ++ L GH + F + ++G
Sbjct: 109 AITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSG 168
Query: 293 DDKLVFIW 300
D +V W
Sbjct: 169 KDTMVKWW 176
Score = 49.6 bits (113), Expect = 5e-05
Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 1/169 (0%)
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
V +W K + I G V C S DG +A +D S ++++L SGE T+
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGH 106
Query: 189 KGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILT 248
K L + G +A + ++ ++D+ + + H +A+TQ + ++T
Sbjct: 107 KAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVT 166
Query: 249 ASKDGKMKILDLLEGHPIFTLSGHNGPV-NAVNFSPTGDTFSSAGDDKL 296
+ KD +K DL H T+ GH V V S + A D +L
Sbjct: 167 SGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSEL 215
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 1/100 (1%)
Query: 201 GCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
G YVAV +V ++D+R + + VT + P G ++ +DG ++I L
Sbjct: 36 GRYVAVPACE-HVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSL 94
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
L G T +GH + + + G +S D + +W
Sbjct: 95 LSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVW 134
Score = 43.2 bits (97), Expect = 0.005
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 16 QLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR-FQGHDEAVMDVTFSSS 74
+LKGHK+AIT + + TS D V WDL T ++ GH V + S
Sbjct: 144 RLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDL-DTQHCFKTMVGHRTEVWGLVLLSE 202
Query: 75 GKYMASASRDKTVRIW 90
K + + + D +R+W
Sbjct: 203 EKRLITGASDSELRVW 218
>AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3
protein.
Length = 943
Score = 88.2 bits (209), Expect = 1e-16
Identities = 62/244 (25%), Positives = 111/244 (45%), Gaps = 17/244 (6%)
Query: 28 YYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTV 87
++ P D+Q+ + + L+DL HD A+ ++ S + + DK+V
Sbjct: 461 FFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSV 520
Query: 88 RIW-VPTVTGSTGMFKAHS-QTVRSVQFSSD--------GSKIITASD-DKVVKLWSTHK 136
+ W V K S + R++Q D K++ S D VK++
Sbjct: 521 KFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDT 580
Query: 137 HKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHG---L 193
KF S GH V C +S+DG++IA+ S D++ K+W LD G+C +K L H +
Sbjct: 581 LKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDC---HKSLFAHDDSVM 637
Query: 194 HLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDG 253
+L + P A +K +D +Q H++ + +A+ PSG Y++++S D
Sbjct: 638 YLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDK 697
Query: 254 KMKI 257
+++
Sbjct: 698 SLRL 701
Score = 76.2 bits (179), Expect = 5e-13
Identities = 43/151 (28%), Positives = 67/151 (44%)
Query: 24 ITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASR 83
+ + Y+PN + +A S LD +V ++ + GH V+ + S G +A+ S
Sbjct: 552 VLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSA 611
Query: 84 DKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSF 143
D+ V+IW AH +V +QF TA D +K W K + I +
Sbjct: 612 DRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTL 671
Query: 144 VGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
GH + C +S G + S S DKS +LW
Sbjct: 672 EGHHQEIWCLAVSPSGDYVVSSSHDKSLRLW 702
Score = 70.9 bits (166), Expect = 2e-11
Identities = 71/331 (21%), Positives = 142/331 (42%), Gaps = 23/331 (6%)
Query: 2 MEDKVTTPEPCLKKQLK--GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRF 59
+ + TP+P ++ GH++ + L ++ ++ + +++ D S+ +W+ R T++ R
Sbjct: 394 LNPSLPTPQPVRTSRITIGGHRSDVRTLSFSSDNIAVLSAAAD-SIKIWN-RSTLQCIRT 451
Query: 60 QGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSK 119
+ A+ F + + ++ ++++ AH + S+ S D
Sbjct: 452 MTCEYALCSF-FVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRG 510
Query: 120 IITASDDKVVKLW---------STHKHKFISSF--VGHTNWVRCARMSNDGSIIASCSDD 168
+T DK VK W ST K + + V C S + ++A D
Sbjct: 511 FVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLD 570
Query: 169 KSTKLWNLDSGECIHTYKDLKGHGLHLAWHP---SGCYVAVATSHGNVKLYDIRTHNLVQ 225
+ K++ +D+ + + L GH L + G +A ++ NVK++ + + +
Sbjct: 571 CTVKIFYVDT---LKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHK 627
Query: 226 YYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTG 285
H+++V + P TA KD K+K D + I TL GH+ + + SP+G
Sbjct: 628 SLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSG 687
Query: 286 DTFSSAGDDKLVFIW-KTNFTDLSSESKENE 315
D S+ DK + +W +T + E +E E
Sbjct: 688 DYVVSSSHDKSLRLWERTREPLILEEEREME 718
Score = 66.9 bits (156), Expect = 3e-10
Identities = 39/163 (23%), Positives = 74/163 (45%), Gaps = 6/163 (3%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L+G K +T L +P+ +A D S+ ++ L + F GH A+ + + G
Sbjct: 61 LQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGG 120
Query: 77 YMASASRDKTVRIWVPTVTGSTGMF--KAHSQTVRSVQFSSDGSKIITASDDKVVKLWST 134
+AS S+D + +W V +G++ K H + F + + ++T+ D +VK W
Sbjct: 121 RLASGSKDTDIIVW--DVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDL 178
Query: 135 HKHKFISSFVGHTNWV-RCARMSNDGSIIASCSDDKSTKLWNL 176
+ VGH V +S + +I SD + ++W++
Sbjct: 179 DTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSE-LRVWDI 220
Score = 56.8 bits (131), Expect = 3e-07
Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 3/147 (2%)
Query: 45 VLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH 104
V +WDLR + QG + V + S G ++A D ++RI+ F H
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGH 106
Query: 105 SQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIAS 164
+ ++++ G ++ + S D + +W + GH + + A + +++ +
Sbjct: 107 KAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVT 166
Query: 165 CSDDKSTKLWNLDSGECIHTYKDLKGH 191
D K W+LD+ C +K + GH
Sbjct: 167 SGKDTMVKWWDLDTQHC---FKTMVGH 190
Score = 52.4 bits (120), Expect = 7e-06
Identities = 29/128 (22%), Positives = 58/128 (45%)
Query: 173 LWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE 232
+W+L GE I + LK L P G ++AV G+++++ + + ++ H
Sbjct: 49 IWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKA 108
Query: 233 AVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
A+T + G + + SKD + + D++ ++ L GH + F + ++G
Sbjct: 109 AITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSG 168
Query: 293 DDKLVFIW 300
D +V W
Sbjct: 169 KDTMVKWW 176
Score = 49.6 bits (113), Expect = 5e-05
Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 1/169 (0%)
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
V +W K + I G V C S DG +A +D S ++++L SGE T+
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGH 106
Query: 189 KGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILT 248
K L + G +A + ++ ++D+ + + H +A+TQ + ++T
Sbjct: 107 KAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVT 166
Query: 249 ASKDGKMKILDLLEGHPIFTLSGHNGPV-NAVNFSPTGDTFSSAGDDKL 296
+ KD +K DL H T+ GH V V S + A D +L
Sbjct: 167 SGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSEL 215
Score = 48.0 bits (109), Expect = 2e-04
Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 1/100 (1%)
Query: 201 GCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDL 260
G YVAV +V ++D+R + + VT + P G ++ +DG ++I L
Sbjct: 36 GRYVAVPACE-HVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSL 94
Query: 261 LEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
L G T +GH + + + G +S D + +W
Sbjct: 95 LSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVW 134
Score = 43.2 bits (97), Expect = 0.005
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 16 QLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYR-FQGHDEAVMDVTFSSS 74
+LKGHK+AIT + + TS D V WDL T ++ GH V + S
Sbjct: 144 RLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDL-DTQHCFKTMVGHRTEVWGLVLLSE 202
Query: 75 GKYMASASRDKTVRIW 90
K + + + D +R+W
Sbjct: 203 EKRLITGASDSELRVW 218
>M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transducin
beta-1 subunit mRNA, 3' end. ).
Length = 247
Score = 87.8 bits (208), Expect = 2e-16
Identities = 59/241 (24%), Positives = 106/241 (43%), Gaps = 7/241 (2%)
Query: 66 VMDVTFSSSGKYMASASRDKTVRIW-VPTVTGSTGMFK---AHSQTVRSVQFSSDGSKII 121
VM ++ SG Y+A D I+ + T G+ + + H+ + +F D ++I+
Sbjct: 7 VMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDD-NQIV 65
Query: 122 TASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGEC 181
T+S D LW + ++F GHT V ++ D + S + D S KLW++ G C
Sbjct: 66 TSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMC 125
Query: 182 IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE--AVTQVAI 239
T+ + + + P+G A + +L+D+R + YS N +T V+
Sbjct: 126 RQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSF 185
Query: 240 HPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFI 299
SG +L D + D L+ L+GH+ V+ + + G ++ D + I
Sbjct: 186 SKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKI 245
Query: 300 W 300
W
Sbjct: 246 W 246
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/160 (28%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
GH + +L P+ + + + D S LWD+R M F GH+ + + F +G
Sbjct: 89 GHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF 148
Query: 79 ASASRDKTVRIWVPTVTGSTGMFKAHSQTV---RSVQFSSDGSKIITASDDKVVKLWSTH 135
A+ S D T R++ M +H + SV FS G ++ DD +W
Sbjct: 149 ATGSDDATCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 207
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWN 175
K GH N V C +++DG +A+ S D K+WN
Sbjct: 208 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 247
Score = 64.9 bits (151), Expect = 1e-09
Identities = 37/166 (22%), Positives = 74/166 (44%), Gaps = 5/166 (3%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFS 72
+ ++L GH ++ + +D QI TSS D + LWD+ ++ F GH VM ++ +
Sbjct: 42 VSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLA 100
Query: 73 SSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLW 132
+ S + D + ++W F H + ++ F +G+ T SDD +L+
Sbjct: 101 PDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 160
Query: 133 STHKHKFISSFVGHTN---WVRCARMSNDGSIIASCSDDKSTKLWN 175
+ + ++ H N + S G ++ + DD + +W+
Sbjct: 161 DLRADQELMTY-SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD 205
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 10 EPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDV 69
E ++ GH++ I A+ + PN AT S D + L+DLR + HD + +
Sbjct: 122 EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGI 180
Query: 70 T---FSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDD 126
T FS SG+ + + D +W G+ H V + + DG + T S D
Sbjct: 181 TSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWD 240
Query: 127 KVVKLWS 133
+K+W+
Sbjct: 241 SFLKIWN 247
>BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat domain
containing 11 protein.
Length = 529
Score = 87.8 bits (208), Expect = 2e-16
Identities = 54/183 (29%), Positives = 96/183 (52%), Gaps = 15/183 (8%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CLK L GH ++ L Y+ ++ I T S D++V +WD+ H+EAV+ + F
Sbjct: 259 CLKV-LTGHTGSVLCLQYD--ERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF 315
Query: 72 SSSGKYMASASRDKTVRIW-VPTVTGST--GMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
S+ M + S+D+++ +W + + T T + H V V F D I++AS D+
Sbjct: 316 SNG--LMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRT 371
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+K+WST +F+ + GH + C + + ++ S S D + +LW+++ G C+ L
Sbjct: 372 IKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRV---L 426
Query: 189 KGH 191
+GH
Sbjct: 427 EGH 429
Score = 70.9 bits (166), Expect = 2e-11
Identities = 72/282 (25%), Positives = 122/282 (43%), Gaps = 26/282 (9%)
Query: 32 NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWV 91
+D++I + DNS+ +WD GH +V+ + + + + + S D TVR+W
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE--RVIVTGSSDSTVRVWD 293
Query: 92 PTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFIS---SFVGHTN 148
H++ V ++FS+ ++T S D+ + +W I+ VGH
Sbjct: 294 VNTGEVLNTLIHHNEAVLHLRFSN--GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA 351
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V + D I S S D++ K+W+ + E + T L GH +A + V+
Sbjct: 352 AVNV--VDFDDKYIVSASGDRTIKVWSTSTCEFVRT---LNGHKRGIACLQYRDRLVVSG 406
Query: 209 SHGN-VKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEG-HP- 265
S N ++L+DI ++ H E V I I++ + DGK+K+ DL P
Sbjct: 407 SSDNTIRLWDIECGACLRVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPR 464
Query: 266 -------IFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ TL H+G V + F SS+ DD + IW
Sbjct: 465 APASTLCLRTLVEHSGRVFRLQFDEF-QIISSSHDD-TILIW 504
Score = 65.7 bits (153), Expect = 7e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 13/163 (7%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRG----TMRSYRFQGHDEAVMDVTFSSSG 75
H A+ L ++ + + T S D S+ +WD+ T+R GH AV V F
Sbjct: 306 HNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRV-LVGHRAAVNVVDFDD-- 360
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
KY+ SAS D+T+++W + H + + +Q+ +++ S D ++LW
Sbjct: 361 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIE 418
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
+ GH VRC R N I++ D K K+W+L +
Sbjct: 419 CGACLRVLEGHEELVRCIRFDNK-RIVSGAYDGK-IKVWDLQA 459
Score = 56.0 bits (129), Expect = 6e-07
Identities = 45/200 (22%), Positives = 88/200 (44%), Gaps = 13/200 (6%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
+S+ V +Q+ D KII+ D +K+W + + GHT V C + D +I
Sbjct: 226 NSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLC--LQYDERVIV 281
Query: 164 SCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNL 223
+ S D + ++W++++GE ++T LHL + S + + ++ ++D+ +
Sbjct: 282 TGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATD 339
Query: 224 VQYYSI---HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ + H AV V YI++AS D +K+ + TL+GH + +
Sbjct: 340 ITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQ 397
Query: 281 FSPTGDTFSSAGDDKLVFIW 300
+ S D + +W
Sbjct: 398 YRDR--LVVSGSSDNTIRLW 415
>BC007620-1|AAH07620.1| 570|Homo sapiens TBL3 protein protein.
Length = 570
Score = 87.8 bits (208), Expect = 2e-16
Identities = 70/334 (20%), Positives = 143/334 (42%), Gaps = 22/334 (6%)
Query: 13 LKKQLKGHKNAITAL-YYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
L+KQ G+ + + + P D + +S + +++L+ T GH + V+ +
Sbjct: 88 LQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQ-TSACQILHGHTDIVLALDV 146
Query: 72 SSSGKYMASASRDKTVRIWVPTVTGST---GMFKAHSQTVRSVQFSS-DGSKIITASDDK 127
G AS ++D++VRIW G H+ +V +V S S ++T S D
Sbjct: 147 FRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDC 206
Query: 128 VVKLWSTHKHKFISSFVG---------------HTNWVRCARMSNDGSIIASCSDDKSTK 172
VKLW K + H + ++ + ++A+ S D++ K
Sbjct: 207 TVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAK 266
Query: 173 LWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNE 232
LW L + + + + + + P +A A++ G +KL+ ++ + ++ + H+
Sbjct: 267 LWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDA 326
Query: 233 AVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAG 292
+V +VA G+ +L++ DG +K+ + + TL H V ++ S D +
Sbjct: 327 SVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGA 386
Query: 293 DDKLVFIWKTNFTDLSSESKENEGQNMITGQRHL 326
D V +WK + T+ ++ + + Q+ L
Sbjct: 387 SDSRVILWK-DVTEAEQAEEQARQEEQVVRQQEL 419
Score = 74.9 bits (176), Expect = 1e-12
Identities = 68/287 (23%), Positives = 126/287 (43%), Gaps = 25/287 (8%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF-SSSGKYMASASRDKTVRIWVPTV 94
+ T++ D+++LL++ R +F G+ E V+DV F ++ AS ++++
Sbjct: 69 VLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVF-ELQ 127
Query: 95 TGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKH---KFISSFVGHTN--- 148
T + + H+ V ++ G + + D+ V++W +K ++ GHT+
Sbjct: 128 TSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVG 187
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNL-----------DSGECI---HTYKDLKGHGLH 194
V C+R+ S + + S D + KLW L D+G + T + ++
Sbjct: 188 TVCCSRLKE--SFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDIN 245
Query: 195 -LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDG 253
+A P+ +A + KL+ + L+ +S H + V P + TAS DG
Sbjct: 246 SVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADG 305
Query: 254 KMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+K+ L + + T GH+ V V F G S+G D LV +W
Sbjct: 306 TIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLW 352
Score = 68.1 bits (159), Expect = 1e-10
Identities = 36/124 (29%), Positives = 57/124 (45%)
Query: 9 PEPCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMD 68
P+ L GH+ + + ++P DQ +AT+S D ++ LW L+ F+GHD +V+
Sbjct: 271 PQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLK 330
Query: 69 VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
V F S G + S+ D V++W AH V + S +T + D
Sbjct: 331 VAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSR 390
Query: 129 VKLW 132
V LW
Sbjct: 391 VILW 394
Score = 61.7 bits (143), Expect = 1e-08
Identities = 42/154 (27%), Positives = 74/154 (48%), Gaps = 7/154 (4%)
Query: 155 MSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAW----HPSGCYVAVATSH 210
+ + G + D + ++W SG+C++T G G L H +G V AT+
Sbjct: 17 VKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTLAHTAG-VVLTATAD 75
Query: 211 GNVKLYDIRTHNLVQYYSIHNEAVTQVA-IHPSGSYILTASKDGKMKILDLLEGHPIFTL 269
N+ LY+ R+ L + ++ ++E V V + P S+++ AS +K+ + L+ L
Sbjct: 76 HNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFE-LQTSACQIL 134
Query: 270 SGHNGPVNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
GH V A++ G F+S D+ V IW+ N
Sbjct: 135 HGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMN 168
Score = 54.0 bits (124), Expect = 2e-06
Identities = 53/260 (20%), Positives = 105/260 (40%), Gaps = 21/260 (8%)
Query: 61 GHDEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQF-SSDGSK 119
G + + T + + + +A+ D + ++ F +S+ V V+F + S
Sbjct: 52 GPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSH 111
Query: 120 IITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSG 179
++ AS+ +K++ GHT+ V + G + ASC+ D+S ++W ++
Sbjct: 112 VVVASNSPCLKVFELQTSA-CQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKA 170
Query: 180 ECIHTYKDLKGH----GLHLAWHPSGCYVAVATSHGNVKLYD----IRTHN--------L 223
+ GH G ++ + VKL+ + + N L
Sbjct: 171 GQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPIL 230
Query: 224 VQYYS---IHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+Q + H++ + VAI P+ + T S+D K+ L + + SGH + V
Sbjct: 231 LQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQ 290
Query: 281 FSPTGDTFSSAGDDKLVFIW 300
FSP ++A D + +W
Sbjct: 291 FSPMDQVLATASADGTIKLW 310
Score = 35.1 bits (77), Expect = 1.2
Identities = 46/225 (20%), Positives = 88/225 (39%), Gaps = 15/225 (6%)
Query: 63 DEAVMDVTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAH----SQTVRSVQFSSDGS 118
+E V + S G Y +A T+R+W +G +A Q + +
Sbjct: 9 EEPVSQLGVKSPGLYFLTAGDQGTLRVW-EAASGQCVYTQAQPPGPGQELTHCTLAHTAG 67
Query: 119 KIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCAR-MSNDGSIIASCSDDKSTKLWNLD 177
++TA+ D + L+ + F G++ V R + + S + S+ K++ L
Sbjct: 68 VVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLKVFELQ 127
Query: 178 SGEC--IHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYY---SIHNE 232
+ C +H + D+ L L G A +V+++ + V S H
Sbjct: 128 TSACQILHGHTDIV---LALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTH 184
Query: 233 AV-TQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPV 276
+V T S+++T S+D +K+ L + + NGP+
Sbjct: 185 SVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPI 229
>AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b
protein.
Length = 542
Score = 87.8 bits (208), Expect = 2e-16
Identities = 54/183 (29%), Positives = 96/183 (52%), Gaps = 15/183 (8%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CLK L GH ++ L Y+ ++ I T S D++V +WD+ H+EAV+ + F
Sbjct: 272 CLKV-LTGHTGSVLCLQYD--ERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF 328
Query: 72 SSSGKYMASASRDKTVRIW-VPTVTGST--GMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
S+ M + S+D+++ +W + + T T + H V V F D I++AS D+
Sbjct: 329 SNG--LMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRT 384
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+K+WST +F+ + GH + C + + ++ S S D + +LW+++ G C+ L
Sbjct: 385 IKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRV---L 439
Query: 189 KGH 191
+GH
Sbjct: 440 EGH 442
Score = 70.9 bits (166), Expect = 2e-11
Identities = 72/282 (25%), Positives = 122/282 (43%), Gaps = 26/282 (9%)
Query: 32 NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWV 91
+D++I + DNS+ +WD GH +V+ + + + + + S D TVR+W
Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE--RVIVTGSSDSTVRVWD 306
Query: 92 PTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFIS---SFVGHTN 148
H++ V ++FS+ ++T S D+ + +W I+ VGH
Sbjct: 307 VNTGEVLNTLIHHNEAVLHLRFSN--GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA 364
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V + D I S S D++ K+W+ + E + T L GH +A + V+
Sbjct: 365 AVNV--VDFDDKYIVSASGDRTIKVWSTSTCEFVRT---LNGHKRGIACLQYRDRLVVSG 419
Query: 209 SHGN-VKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEG-HP- 265
S N ++L+DI ++ H E V I I++ + DGK+K+ DL P
Sbjct: 420 SSDNTIRLWDIECGACLRVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPR 477
Query: 266 -------IFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ TL H+G V + F SS+ DD + IW
Sbjct: 478 APASTLCLRTLVEHSGRVFRLQFDEF-QIISSSHDD-TILIW 517
Score = 65.7 bits (153), Expect = 7e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 13/163 (7%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRG----TMRSYRFQGHDEAVMDVTFSSSG 75
H A+ L ++ + + T S D S+ +WD+ T+R GH AV V F
Sbjct: 319 HNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRV-LVGHRAAVNVVDFDD-- 373
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
KY+ SAS D+T+++W + H + + +Q+ +++ S D ++LW
Sbjct: 374 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIE 431
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
+ GH VRC R N I++ D K K+W+L +
Sbjct: 432 CGACLRVLEGHEELVRCIRFDNK-RIVSGAYDGK-IKVWDLQA 472
Score = 56.0 bits (129), Expect = 6e-07
Identities = 45/200 (22%), Positives = 88/200 (44%), Gaps = 13/200 (6%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
+S+ V +Q+ D KII+ D +K+W + + GHT V C + D +I
Sbjct: 239 NSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLC--LQYDERVIV 294
Query: 164 SCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNL 223
+ S D + ++W++++GE ++T LHL + S + + ++ ++D+ +
Sbjct: 295 TGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATD 352
Query: 224 VQYYSI---HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ + H AV V YI++AS D +K+ + TL+GH + +
Sbjct: 353 ITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQ 410
Query: 281 FSPTGDTFSSAGDDKLVFIW 300
+ S D + +W
Sbjct: 411 YRDR--LVVSGSSDNTIRLW 428
>AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform C protein.
Length = 542
Score = 87.8 bits (208), Expect = 2e-16
Identities = 54/183 (29%), Positives = 96/183 (52%), Gaps = 15/183 (8%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CLK L GH ++ L Y+ ++ I T S D++V +WD+ H+EAV+ + F
Sbjct: 272 CLKV-LTGHTGSVLCLQYD--ERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF 328
Query: 72 SSSGKYMASASRDKTVRIW-VPTVTGST--GMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
S+ M + S+D+++ +W + + T T + H V V F D I++AS D+
Sbjct: 329 SNG--LMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRT 384
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+K+WST +F+ + GH + C + + ++ S S D + +LW+++ G C+ L
Sbjct: 385 IKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRV---L 439
Query: 189 KGH 191
+GH
Sbjct: 440 EGH 442
Score = 70.9 bits (166), Expect = 2e-11
Identities = 72/282 (25%), Positives = 122/282 (43%), Gaps = 26/282 (9%)
Query: 32 NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWV 91
+D++I + DNS+ +WD GH +V+ + + + + + S D TVR+W
Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE--RVIVTGSSDSTVRVWD 306
Query: 92 PTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFIS---SFVGHTN 148
H++ V ++FS+ ++T S D+ + +W I+ VGH
Sbjct: 307 VNTGEVLNTLIHHNEAVLHLRFSN--GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA 364
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V + D I S S D++ K+W+ + E + T L GH +A + V+
Sbjct: 365 AVNV--VDFDDKYIVSASGDRTIKVWSTSTCEFVRT---LNGHKRGIACLQYRDRLVVSG 419
Query: 209 SHGN-VKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEG-HP- 265
S N ++L+DI ++ H E V I I++ + DGK+K+ DL P
Sbjct: 420 SSDNTIRLWDIECGACLRVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPR 477
Query: 266 -------IFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ TL H+G V + F SS+ DD + IW
Sbjct: 478 APASTLCLRTLVEHSGRVFRLQFDEF-QIISSSHDD-TILIW 517
Score = 65.7 bits (153), Expect = 7e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 13/163 (7%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRG----TMRSYRFQGHDEAVMDVTFSSSG 75
H A+ L ++ + + T S D S+ +WD+ T+R GH AV V F
Sbjct: 319 HNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRV-LVGHRAAVNVVDFDD-- 373
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
KY+ SAS D+T+++W + H + + +Q+ +++ S D ++LW
Sbjct: 374 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIE 431
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
+ GH VRC R N I++ D K K+W+L +
Sbjct: 432 CGACLRVLEGHEELVRCIRFDNK-RIVSGAYDGK-IKVWDLQA 472
Score = 56.0 bits (129), Expect = 6e-07
Identities = 45/200 (22%), Positives = 88/200 (44%), Gaps = 13/200 (6%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
+S+ V +Q+ D KII+ D +K+W + + GHT V C + D +I
Sbjct: 239 NSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLC--LQYDERVIV 294
Query: 164 SCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNL 223
+ S D + ++W++++GE ++T LHL + S + + ++ ++D+ +
Sbjct: 295 TGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATD 352
Query: 224 VQYYSI---HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ + H AV V YI++AS D +K+ + TL+GH + +
Sbjct: 353 ITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQ 410
Query: 281 FSPTGDTFSSAGDDKLVFIW 300
+ S D + +W
Sbjct: 411 YRDR--LVVSGSSDNTIRLW 428
>AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform B protein.
Length = 529
Score = 87.8 bits (208), Expect = 2e-16
Identities = 54/183 (29%), Positives = 96/183 (52%), Gaps = 15/183 (8%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CLK L GH ++ L Y+ ++ I T S D++V +WD+ H+EAV+ + F
Sbjct: 259 CLKV-LTGHTGSVLCLQYD--ERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF 315
Query: 72 SSSGKYMASASRDKTVRIW-VPTVTGST--GMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
S+ M + S+D+++ +W + + T T + H V V F D I++AS D+
Sbjct: 316 SNG--LMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRT 371
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+K+WST +F+ + GH + C + + ++ S S D + +LW+++ G C+ L
Sbjct: 372 IKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRV---L 426
Query: 189 KGH 191
+GH
Sbjct: 427 EGH 429
Score = 70.9 bits (166), Expect = 2e-11
Identities = 72/282 (25%), Positives = 122/282 (43%), Gaps = 26/282 (9%)
Query: 32 NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWV 91
+D++I + DNS+ +WD GH +V+ + + + + + S D TVR+W
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE--RVIVTGSSDSTVRVWD 293
Query: 92 PTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFIS---SFVGHTN 148
H++ V ++FS+ ++T S D+ + +W I+ VGH
Sbjct: 294 VNTGEVLNTLIHHNEAVLHLRFSN--GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA 351
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V + D I S S D++ K+W+ + E + T L GH +A + V+
Sbjct: 352 AVNV--VDFDDKYIVSASGDRTIKVWSTSTCEFVRT---LNGHKRGIACLQYRDRLVVSG 406
Query: 209 SHGN-VKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEG-HP- 265
S N ++L+DI ++ H E V I I++ + DGK+K+ DL P
Sbjct: 407 SSDNTIRLWDIECGACLRVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPR 464
Query: 266 -------IFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ TL H+G V + F SS+ DD + IW
Sbjct: 465 APASTLCLRTLVEHSGRVFRLQFDEF-QIISSSHDD-TILIW 504
Score = 65.7 bits (153), Expect = 7e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 13/163 (7%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRG----TMRSYRFQGHDEAVMDVTFSSSG 75
H A+ L ++ + + T S D S+ +WD+ T+R GH AV V F
Sbjct: 306 HNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRV-LVGHRAAVNVVDFDD-- 360
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
KY+ SAS D+T+++W + H + + +Q+ +++ S D ++LW
Sbjct: 361 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIE 418
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
+ GH VRC R N I++ D K K+W+L +
Sbjct: 419 CGACLRVLEGHEELVRCIRFDNK-RIVSGAYDGK-IKVWDLQA 459
Score = 56.0 bits (129), Expect = 6e-07
Identities = 45/200 (22%), Positives = 88/200 (44%), Gaps = 13/200 (6%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
+S+ V +Q+ D KII+ D +K+W + + GHT V C + D +I
Sbjct: 226 NSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLC--LQYDERVIV 281
Query: 164 SCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNL 223
+ S D + ++W++++GE ++T LHL + S + + ++ ++D+ +
Sbjct: 282 TGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATD 339
Query: 224 VQYYSI---HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ + H AV V YI++AS D +K+ + TL+GH + +
Sbjct: 340 ITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQ 397
Query: 281 FSPTGDTFSSAGDDKLVFIW 300
+ S D + +W
Sbjct: 398 YRDR--LVVSGSSDNTIRLW 415
>AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform A protein.
Length = 508
Score = 87.8 bits (208), Expect = 2e-16
Identities = 54/183 (29%), Positives = 96/183 (52%), Gaps = 15/183 (8%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CLK L GH ++ L Y+ ++ I T S D++V +WD+ H+EAV+ + F
Sbjct: 238 CLKV-LTGHTGSVLCLQYD--ERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF 294
Query: 72 SSSGKYMASASRDKTVRIW-VPTVTGST--GMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
S+ M + S+D+++ +W + + T T + H V V F D I++AS D+
Sbjct: 295 SNG--LMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRT 350
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+K+WST +F+ + GH + C + + ++ S S D + +LW+++ G C+ L
Sbjct: 351 IKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRV---L 405
Query: 189 KGH 191
+GH
Sbjct: 406 EGH 408
Score = 70.9 bits (166), Expect = 2e-11
Identities = 72/282 (25%), Positives = 122/282 (43%), Gaps = 26/282 (9%)
Query: 32 NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWV 91
+D++I + DNS+ +WD GH +V+ + + + + + S D TVR+W
Sbjct: 215 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE--RVIVTGSSDSTVRVWD 272
Query: 92 PTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFIS---SFVGHTN 148
H++ V ++FS+ ++T S D+ + +W I+ VGH
Sbjct: 273 VNTGEVLNTLIHHNEAVLHLRFSN--GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA 330
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V + D I S S D++ K+W+ + E + T L GH +A + V+
Sbjct: 331 AVNV--VDFDDKYIVSASGDRTIKVWSTSTCEFVRT---LNGHKRGIACLQYRDRLVVSG 385
Query: 209 SHGN-VKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEG-HP- 265
S N ++L+DI ++ H E V I I++ + DGK+K+ DL P
Sbjct: 386 SSDNTIRLWDIECGACLRVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPR 443
Query: 266 -------IFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ TL H+G V + F SS+ DD + IW
Sbjct: 444 APASTLCLRTLVEHSGRVFRLQFDEF-QIISSSHDD-TILIW 483
Score = 65.7 bits (153), Expect = 7e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 13/163 (7%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRG----TMRSYRFQGHDEAVMDVTFSSSG 75
H A+ L ++ + + T S D S+ +WD+ T+R GH AV V F
Sbjct: 285 HNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRV-LVGHRAAVNVVDFDD-- 339
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
KY+ SAS D+T+++W + H + + +Q+ +++ S D ++LW
Sbjct: 340 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIE 397
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
+ GH VRC R N I++ D K K+W+L +
Sbjct: 398 CGACLRVLEGHEELVRCIRFDNK-RIVSGAYDGK-IKVWDLQA 438
Score = 56.0 bits (129), Expect = 6e-07
Identities = 45/200 (22%), Positives = 88/200 (44%), Gaps = 13/200 (6%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
+S+ V +Q+ D KII+ D +K+W + + GHT V C + D +I
Sbjct: 205 NSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLC--LQYDERVIV 260
Query: 164 SCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNL 223
+ S D + ++W++++GE ++T LHL + S + + ++ ++D+ +
Sbjct: 261 TGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATD 318
Query: 224 VQYYSI---HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ + H AV V YI++AS D +K+ + TL+GH + +
Sbjct: 319 ITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQ 376
Query: 281 FSPTGDTFSSAGDDKLVFIW 300
+ S D + +W
Sbjct: 377 YRDR--LVVSGSSDNTIRLW 394
>AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein.
Length = 550
Score = 87.8 bits (208), Expect = 2e-16
Identities = 54/183 (29%), Positives = 96/183 (52%), Gaps = 15/183 (8%)
Query: 12 CLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTF 71
CLK L GH ++ L Y+ ++ I T S D++V +WD+ H+EAV+ + F
Sbjct: 280 CLKV-LTGHTGSVLCLQYD--ERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF 336
Query: 72 SSSGKYMASASRDKTVRIW-VPTVTGST--GMFKAHSQTVRSVQFSSDGSKIITASDDKV 128
S+ M + S+D+++ +W + + T T + H V V F D I++AS D+
Sbjct: 337 SNG--LMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRT 392
Query: 129 VKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDL 188
+K+WST +F+ + GH + C + + ++ S S D + +LW+++ G C+ L
Sbjct: 393 IKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRV---L 447
Query: 189 KGH 191
+GH
Sbjct: 448 EGH 450
Score = 70.9 bits (166), Expect = 2e-11
Identities = 72/282 (25%), Positives = 122/282 (43%), Gaps = 26/282 (9%)
Query: 32 NDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIWV 91
+D++I + DNS+ +WD GH +V+ + + + + + S D TVR+W
Sbjct: 257 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDE--RVIVTGSSDSTVRVWD 314
Query: 92 PTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFIS---SFVGHTN 148
H++ V ++FS+ ++T S D+ + +W I+ VGH
Sbjct: 315 VNTGEVLNTLIHHNEAVLHLRFSN--GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA 372
Query: 149 WVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVAT 208
V + D I S S D++ K+W+ + E + T L GH +A + V+
Sbjct: 373 AVNV--VDFDDKYIVSASGDRTIKVWSTSTCEFVRT---LNGHKRGIACLQYRDRLVVSG 427
Query: 209 SHGN-VKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEG-HP- 265
S N ++L+DI ++ H E V I I++ + DGK+K+ DL P
Sbjct: 428 SSDNTIRLWDIECGACLRVLEGHEELVR--CIRFDNKRIVSGAYDGKIKVWDLQAALDPR 485
Query: 266 -------IFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
+ TL H+G V + F SS+ DD + IW
Sbjct: 486 APASTLCLRTLVEHSGRVFRLQFDEF-QIISSSHDD-TILIW 525
Score = 65.7 bits (153), Expect = 7e-10
Identities = 44/163 (26%), Positives = 74/163 (45%), Gaps = 13/163 (7%)
Query: 20 HKNAITALYYNPNDQQIATSSLDNSVLLWDLRG----TMRSYRFQGHDEAVMDVTFSSSG 75
H A+ L ++ + + T S D S+ +WD+ T+R GH AV V F
Sbjct: 327 HNEAVLHLRFS--NGLMVTCSKDRSIAVWDMASATDITLRRV-LVGHRAAVNVVDFDD-- 381
Query: 76 KYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTH 135
KY+ SAS D+T+++W + H + + +Q+ +++ S D ++LW
Sbjct: 382 KYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIE 439
Query: 136 KHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDS 178
+ GH VRC R N I++ D K K+W+L +
Sbjct: 440 CGACLRVLEGHEELVRCIRFDNK-RIVSGAYDGK-IKVWDLQA 480
Score = 56.0 bits (129), Expect = 6e-07
Identities = 45/200 (22%), Positives = 88/200 (44%), Gaps = 13/200 (6%)
Query: 104 HSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
+S+ V +Q+ D KII+ D +K+W + + GHT V C + D +I
Sbjct: 247 NSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLC--LQYDERVIV 302
Query: 164 SCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIRTHNL 223
+ S D + ++W++++GE ++T LHL + S + + ++ ++D+ +
Sbjct: 303 TGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATD 360
Query: 224 VQYYSI---HNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVN 280
+ + H AV V YI++AS D +K+ + TL+GH + +
Sbjct: 361 ITLRRVLVGHRAAVNVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQ 418
Query: 281 FSPTGDTFSSAGDDKLVFIW 300
+ S D + +W
Sbjct: 419 YRDR--LVVSGSSDNTIRLW 436
>BC034964-1|AAH34964.1| 920|Homo sapiens WD repeat domain 47
protein.
Length = 920
Score = 87.4 bits (207), Expect = 2e-16
Identities = 74/268 (27%), Positives = 116/268 (43%), Gaps = 19/268 (7%)
Query: 54 MRSYRFQGHDEAVMDVTFSSSGKYMASASRDKTVRIW-----VPTVTGSTGMFKAHSQTV 108
+R R + H ++ V +S G+ +A+ S DK V++ TG F H T+
Sbjct: 653 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTI 712
Query: 109 RSVQF----SSDGSKIITA-SDDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIA 163
R + F S G+ +I+A + D + + + + + GHT + A + G +IA
Sbjct: 713 RDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI-LALYTWSGWMIA 771
Query: 164 SCSDDKSTKLWNLDSGECIH----TYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR 219
S S DK+ W+L C T+ +A PSG +A + LYDIR
Sbjct: 772 SGSQDKTVGFWDLRVPSCARVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIR 831
Query: 220 THNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKIL----DLLEGHPIFTLSGHNGP 275
+VQ Y H+ V V P Y+LT S D K+K+ DL + PI + H
Sbjct: 832 GGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDK 891
Query: 276 VNAVNFSPTGDTFSSAGDDKLVFIWKTN 303
V + +F S+ D+ V +W N
Sbjct: 892 VIQCRWHTQDLSFLSSSADRTVTLWTYN 919
Score = 50.0 bits (114), Expect = 4e-05
Identities = 57/265 (21%), Positives = 101/265 (38%), Gaps = 20/265 (7%)
Query: 7 TTPEPCLK-KQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL-----RGTMRSYRFQ 60
T +P ++ K+ K HK +I + ++P Q +AT S D V + T F
Sbjct: 647 TPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFS 706
Query: 61 GHDEAVMDVTF----SSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQ-FSS 115
HD + D+ F S G + SA I+ G+ T + ++
Sbjct: 707 MHDGTIRDLAFMEGPESGGAILISAGAG-DCNIYTTDCQRGQGLHALSGHTGHILALYTW 765
Query: 116 DGSKIITASDDKVVKLWSTHKHKFI----SSFVGHTNWVRCARMSNDGSIIASCSDDKST 171
G I + S DK V W ++F G + V + G ++A+ +D S
Sbjct: 766 SGWMIASGSQDKTVGFWDLRVPSCARVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSC 825
Query: 172 KLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGNVKLYDIR---THNL-VQYY 227
L+++ G + +Y + + P Y+ + +K+ D++ T L +
Sbjct: 826 MLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVV 885
Query: 228 SIHNEAVTQVAIHPSGSYILTASKD 252
H + V Q H L++S D
Sbjct: 886 GEHKDKVIQCRWHTQDLSFLSSSAD 910
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 19 GHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKYM 78
G +A+ ++ +P+ + +AT D+S +L+D+RG + H V V FS Y+
Sbjct: 799 GTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYL 858
Query: 79 ASASRDKTVRI--WVPTVTGSTGMFKA--HSQTVRSVQFSSDGSKIITASDDKVVKLWS 133
+ S D +++ +T + H V ++ + +++S D+ V LW+
Sbjct: 859 LTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWT 917
>BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS
box-containing 2 protein.
Length = 404
Score = 87.4 bits (207), Expect = 2e-16
Identities = 60/235 (25%), Positives = 107/235 (45%), Gaps = 16/235 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY-MASASRDKTVRIWVPTV 94
+AT D + +W+++ + GH + V D++F+ SG + SASRDKT+RIW
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185
Query: 95 TGST-GMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCA 153
G + H Q V S D S + +A+ +K V LWS + I GH + V
Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSC 245
Query: 154 RMSNDGSIIASCSDDKSTKLWNLDSGECI----HTYKD--LKGHGLHLA------WHPSG 201
S D +++ + S D + +W+ +GE + HT D + +H++ + P G
Sbjct: 246 DFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEG 305
Query: 202 CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMK 256
Y+A ++++ + + + + N P G I T ++DG ++
Sbjct: 306 LYLATVADDRLLRIWALELKTPIAFAPMTNGLC--CTFFPHGGVIATGTRDGHVQ 358
Score = 78.6 bits (185), Expect = 1e-13
Identities = 64/238 (26%), Positives = 101/238 (42%), Gaps = 18/238 (7%)
Query: 78 MASASRDKTVRIWVPTVTGSTGM-FKAHSQTVRSVQFSSDGSKI-ITASDDKVVKLWSTH 135
+A+ D ++IW TG + H VR + F+ GS I ++AS DK +++W +
Sbjct: 126 LATGLNDGQIKIW-EVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
Query: 136 KH-KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
KH K I GH WV C +S D S++ S + +KS LW++ S I + + +
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVS 244
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRT--------HNLVQYY----SIHNEAVTQVAIHPS 242
+ P + A+ NV ++D T H V +H ++ V P
Sbjct: 245 CDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPE 304
Query: 243 GSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
G Y+ T + D ++I L PI NG F P G ++ D V W
Sbjct: 305 GLYLATVADDRLLRIWALELKTPIAFAPMTNG--LCCTFFPHGGVIATGTRDGHVQFW 360
Score = 63.7 bits (148), Expect = 3e-09
Identities = 42/170 (24%), Positives = 77/170 (45%), Gaps = 14/170 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH + +P+ + +++ + SV LW +R + +GH +V+ FS
Sbjct: 193 LSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSA 252
Query: 77 YMASASRDKTVRIWVP------------TVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+ +AS D V +W P V + H ++RSV FS +G + T +
Sbjct: 253 LLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGLYLATVA 312
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
DD+++++W+ + K +F TN + C G +IA+ + D + W
Sbjct: 313 DDRLLRIWAL-ELKTPIAFAPMTNGL-CCTFFPHGGVIATGTRDGHVQFW 360
Score = 48.0 bits (109), Expect = 2e-04
Identities = 35/133 (26%), Positives = 63/133 (47%), Gaps = 14/133 (10%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWD--LRGTMRSYRFQGHDEAVMD-- 68
L ++L+GH++++ + ++P+ + T+S D +V++WD +RS D A+ D
Sbjct: 231 LIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSD 290
Query: 69 --------VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKI 120
V FS G Y+A+ + D+ +RIW + T + A F G I
Sbjct: 291 VHISSLRSVCFSPEGLYLATVADDRLLRIWALEL--KTPIAFAPMTNGLCCTFFPHGGVI 348
Query: 121 ITASDDKVVKLWS 133
T + D V+ W+
Sbjct: 349 ATGTRDGHVQFWT 361
Score = 47.2 bits (107), Expect = 3e-04
Identities = 33/142 (23%), Positives = 65/142 (45%), Gaps = 2/142 (1%)
Query: 161 IIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN-VKLYDIR 219
++A+ +D K+W + +G + + L++ PSG + V+ S ++++D+
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
Query: 220 THNL-VQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNA 278
H +Q S H + V +I P S + +A+ + + + + I L GH V +
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVS 244
Query: 279 VNFSPTGDTFSSAGDDKLVFIW 300
+FSP +A D V +W
Sbjct: 245 CDFSPDSALLVTASYDTNVIMW 266
Score = 40.3 bits (90), Expect = 0.032
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 246 ILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD-TFSSAGDDKLVFIWKTN 303
+ T DG++KI ++ G + LSGH V ++F+P+G SA DK + IW N
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
>AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD
protein protein.
Length = 404
Score = 87.4 bits (207), Expect = 2e-16
Identities = 60/235 (25%), Positives = 107/235 (45%), Gaps = 16/235 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY-MASASRDKTVRIWVPTV 94
+AT D + +W+++ + GH + V D++F+ SG + SASRDKT+RIW
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185
Query: 95 TGST-GMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCA 153
G + H Q V S D S + +A+ +K V LWS + I GH + V
Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSC 245
Query: 154 RMSNDGSIIASCSDDKSTKLWNLDSGECI----HTYKD--LKGHGLHLA------WHPSG 201
S D +++ + S D + +W+ +GE + HT D + +H++ + P G
Sbjct: 246 DFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEG 305
Query: 202 CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMK 256
Y+A ++++ + + + + N P G I T ++DG ++
Sbjct: 306 LYLATVADDRLLRIWALELKTPIAFAPMTNGLC--CTFFPHGGVIATGTRDGHVQ 358
Score = 78.6 bits (185), Expect = 1e-13
Identities = 64/238 (26%), Positives = 101/238 (42%), Gaps = 18/238 (7%)
Query: 78 MASASRDKTVRIWVPTVTGSTGM-FKAHSQTVRSVQFSSDGSKI-ITASDDKVVKLWSTH 135
+A+ D ++IW TG + H VR + F+ GS I ++AS DK +++W +
Sbjct: 126 LATGLNDGQIKIW-EVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
Query: 136 KH-KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
KH K I GH WV C +S D S++ S + +KS LW++ S I + + +
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVS 244
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRT--------HNLVQYY----SIHNEAVTQVAIHPS 242
+ P + A+ NV ++D T H V +H ++ V P
Sbjct: 245 CDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPE 304
Query: 243 GSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
G Y+ T + D ++I L PI NG F P G ++ D V W
Sbjct: 305 GLYLATVADDRLLRIWALELKTPIAFAPMTNG--LCCTFFPHGGVIATGTRDGHVQFW 360
Score = 63.7 bits (148), Expect = 3e-09
Identities = 42/170 (24%), Positives = 77/170 (45%), Gaps = 14/170 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH + +P+ + +++ + SV LW +R + +GH +V+ FS
Sbjct: 193 LSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSA 252
Query: 77 YMASASRDKTVRIWVP------------TVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+ +AS D V +W P V + H ++RSV FS +G + T +
Sbjct: 253 LLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGLYLATVA 312
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
DD+++++W+ + K +F TN + C G +IA+ + D + W
Sbjct: 313 DDRLLRIWAL-ELKTPIAFAPMTNGL-CCTFFPHGGVIATGTRDGHVQFW 360
Score = 48.0 bits (109), Expect = 2e-04
Identities = 35/133 (26%), Positives = 63/133 (47%), Gaps = 14/133 (10%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWD--LRGTMRSYRFQGHDEAVMD-- 68
L ++L+GH++++ + ++P+ + T+S D +V++WD +RS D A+ D
Sbjct: 231 LIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSD 290
Query: 69 --------VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKI 120
V FS G Y+A+ + D+ +RIW + T + A F G I
Sbjct: 291 VHISSLRSVCFSPEGLYLATVADDRLLRIWALEL--KTPIAFAPMTNGLCCTFFPHGGVI 348
Query: 121 ITASDDKVVKLWS 133
T + D V+ W+
Sbjct: 349 ATGTRDGHVQFWT 361
Score = 47.2 bits (107), Expect = 3e-04
Identities = 33/142 (23%), Positives = 65/142 (45%), Gaps = 2/142 (1%)
Query: 161 IIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN-VKLYDIR 219
++A+ +D K+W + +G + + L++ PSG + V+ S ++++D+
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
Query: 220 THNL-VQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNA 278
H +Q S H + V +I P S + +A+ + + + + I L GH V +
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVS 244
Query: 279 VNFSPTGDTFSSAGDDKLVFIW 300
+FSP +A D V +W
Sbjct: 245 CDFSPDSALLVTASYDTNVIMW 266
Score = 40.3 bits (90), Expect = 0.032
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 246 ILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD-TFSSAGDDKLVFIWKTN 303
+ T DG++KI ++ G + LSGH V ++F+P+G SA DK + IW N
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
>AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein.
Length = 404
Score = 87.4 bits (207), Expect = 2e-16
Identities = 60/235 (25%), Positives = 107/235 (45%), Gaps = 16/235 (6%)
Query: 36 IATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGKY-MASASRDKTVRIWVPTV 94
+AT D + +W+++ + GH + V D++F+ SG + SASRDKT+RIW
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185
Query: 95 TGST-GMFKAHSQTVRSVQFSSDGSKIITASDDKVVKLWSTHKHKFISSFVGHTNWVRCA 153
G + H Q V S D S + +A+ +K V LWS + I GH + V
Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSC 245
Query: 154 RMSNDGSIIASCSDDKSTKLWNLDSGECI----HTYKD--LKGHGLHLA------WHPSG 201
S D +++ + S D + +W+ +GE + HT D + +H++ + P G
Sbjct: 246 DFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEG 305
Query: 202 CYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAVTQVAIHPSGSYILTASKDGKMK 256
Y+A ++++ + + + + N P G I T ++DG ++
Sbjct: 306 LYLATVADDRLLRIWALELKTPIAFAPMTNGLC--CTFFPHGGVIATGTRDGHVQ 358
Score = 78.6 bits (185), Expect = 1e-13
Identities = 64/238 (26%), Positives = 101/238 (42%), Gaps = 18/238 (7%)
Query: 78 MASASRDKTVRIWVPTVTGSTGM-FKAHSQTVRSVQFSSDGSKI-ITASDDKVVKLWSTH 135
+A+ D ++IW TG + H VR + F+ GS I ++AS DK +++W +
Sbjct: 126 LATGLNDGQIKIW-EVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
Query: 136 KH-KFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLH 194
KH K I GH WV C +S D S++ S + +KS LW++ S I + + +
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVS 244
Query: 195 LAWHPSGCYVAVATSHGNVKLYDIRT--------HNLVQYY----SIHNEAVTQVAIHPS 242
+ P + A+ NV ++D T H V +H ++ V P
Sbjct: 245 CDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPE 304
Query: 243 GSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGDTFSSAGDDKLVFIW 300
G Y+ T + D ++I L PI NG F P G ++ D V W
Sbjct: 305 GLYLATVADDRLLRIWALELKTPIAFAPMTNG--LCCTFFPHGGVIATGTRDGHVQFW 360
Score = 63.7 bits (148), Expect = 3e-09
Identities = 42/170 (24%), Positives = 77/170 (45%), Gaps = 14/170 (8%)
Query: 17 LKGHKNAITALYYNPNDQQIATSSLDNSVLLWDLRGTMRSYRFQGHDEAVMDVTFSSSGK 76
L GH + +P+ + +++ + SV LW +R + +GH +V+ FS
Sbjct: 193 LSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSA 252
Query: 77 YMASASRDKTVRIWVP------------TVTGSTGMFKAHSQTVRSVQFSSDGSKIITAS 124
+ +AS D V +W P V + H ++RSV FS +G + T +
Sbjct: 253 LLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGLYLATVA 312
Query: 125 DDKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLW 174
DD+++++W+ + K +F TN + C G +IA+ + D + W
Sbjct: 313 DDRLLRIWAL-ELKTPIAFAPMTNGL-CCTFFPHGGVIATGTRDGHVQFW 360
Score = 48.0 bits (109), Expect = 2e-04
Identities = 35/133 (26%), Positives = 63/133 (47%), Gaps = 14/133 (10%)
Query: 13 LKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWD--LRGTMRSYRFQGHDEAVMD-- 68
L ++L+GH++++ + ++P+ + T+S D +V++WD +RS D A+ D
Sbjct: 231 LIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSD 290
Query: 69 --------VTFSSSGKYMASASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFSSDGSKI 120
V FS G Y+A+ + D+ +RIW + T + A F G I
Sbjct: 291 VHISSLRSVCFSPEGLYLATVADDRLLRIWALEL--KTPIAFAPMTNGLCCTFFPHGGVI 348
Query: 121 ITASDDKVVKLWS 133
T + D V+ W+
Sbjct: 349 ATGTRDGHVQFWT 361
Score = 47.2 bits (107), Expect = 3e-04
Identities = 33/142 (23%), Positives = 65/142 (45%), Gaps = 2/142 (1%)
Query: 161 IIASCSDDKSTKLWNLDSGECIHTYKDLKGHGLHLAWHPSGCYVAVATSHGN-VKLYDIR 219
++A+ +D K+W + +G + + L++ PSG + V+ S ++++D+
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
Query: 220 THNL-VQYYSIHNEAVTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLSGHNGPVNA 278
H +Q S H + V +I P S + +A+ + + + + I L GH V +
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVS 244
Query: 279 VNFSPTGDTFSSAGDDKLVFIW 300
+FSP +A D V +W
Sbjct: 245 CDFSPDSALLVTASYDTNVIMW 266
Score = 40.3 bits (90), Expect = 0.032
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 246 ILTASKDGKMKILDLLEGHPIFTLSGHNGPVNAVNFSPTGD-TFSSAGDDKLVFIWKTN 303
+ T DG++KI ++ G + LSGH V ++F+P+G SA DK + IW N
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184
>BC002489-1|AAH02489.1| 606|Homo sapiens WD repeat domain 1
protein.
Length = 606
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/342 (21%), Positives = 142/342 (41%), Gaps = 22/342 (6%)
Query: 11 PCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL--RGTMRSYRFQGHDEAVMD 68
P L H + + Y P+ IA+ + + +WD + + Y +Q + D
Sbjct: 48 PALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKD 107
Query: 69 VTFSSSGKYMA--SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFS-SDGSKIITASD 125
+ ++ K +A R+K +++ S G H++ + SV S ++ T SD
Sbjct: 108 IAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSD 167
Query: 126 DKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
D + KF + H+ +V C R S DG+ A+ S D +++ +GE +
Sbjct: 168 DNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCAL 227
Query: 186 KDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV-TQVAIHP 241
K H G++ ++W P ++ A+ K++D+ +++V + + + + Q+
Sbjct: 228 GGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLW 287
Query: 242 SGSYILTASKDGKMKILDLLE-GHPIFTLSGHNGPVNAVNFSPTG--DTFSSAGDDKLVF 298
++L+ S G + LD P+ + GH+ + + G S D +
Sbjct: 288 QKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHIN 347
Query: 299 IWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQI 340
W SE+ EN+ G+ H + T+ E+GQ+
Sbjct: 348 YW-------DSETGENDS---FAGKGHTNQVSRMTVDESGQL 379
Score = 61.7 bits (143), Expect = 1e-08
Identities = 62/295 (21%), Positives = 121/295 (41%), Gaps = 16/295 (5%)
Query: 60 QGHDEAVMDVTFSSSG--KYMASASRDKTVRIWVPTVTGSTGMF--KAHSQTVRSVQFSS 115
+GH +++ +T +G Y+ S S D + W + TG F K H+ V +
Sbjct: 317 KGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYW-DSETGENDSFAGKGHTNQVSRMTVDE 375
Query: 116 DGSKIITASDDKVVKLWSTHKHKFISSFVGHTN-WVRCARMSNDGSIIASCSDDKSTKLW 174
G ++I+ S D V+ S + V + +C + G + C +
Sbjct: 376 SG-QLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQI---VL 431
Query: 175 NLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
D +C D G+ + A HP G VA+ GNV+LY I L +
Sbjct: 432 LKDQRKCFSI--DNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAK 489
Query: 234 --VTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSS 290
VT VA G+++ + + + +G+ + GH+ + + +SP + F+S
Sbjct: 490 GPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFAS 549
Query: 291 AGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQIQDVNI 345
G D +V++W + + + ++ + ++ L E + T + + +++ I
Sbjct: 550 GGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTI 604
>AF020260-1|AAD05045.1| 534|Homo sapiens WDR1 protein protein.
Length = 534
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/342 (21%), Positives = 142/342 (41%), Gaps = 22/342 (6%)
Query: 11 PCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL--RGTMRSYRFQGHDEAVMD 68
P L H + + Y P+ IA+ + + +WD + + Y +Q + D
Sbjct: 48 PALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKD 107
Query: 69 VTFSSSGKYMA--SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFS-SDGSKIITASD 125
+ ++ K +A R+K +++ S G H++ + SV S ++ T SD
Sbjct: 108 IAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSD 167
Query: 126 DKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
D + KF + H+ +V C R S DG+ A+ S D +++ +GE +
Sbjct: 168 DNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCAL 227
Query: 186 KDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV-TQVAIHP 241
K H G++ ++W P ++ A+ K++D+ +++V + + + + Q+
Sbjct: 228 GGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLW 287
Query: 242 SGSYILTASKDGKMKILDLLE-GHPIFTLSGHNGPVNAVNFSPTG--DTFSSAGDDKLVF 298
++L+ S G + LD P+ + GH+ + + G S D +
Sbjct: 288 QKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHIN 347
Query: 299 IWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQI 340
W SE+ EN+ G+ H + T+ E+GQ+
Sbjct: 348 YW-------DSETGENDS---FAGKGHTNQVSRMTVDESGQL 379
Score = 40.7 bits (91), Expect = 0.024
Identities = 48/213 (22%), Positives = 83/213 (38%), Gaps = 15/213 (7%)
Query: 60 QGHDEAVMDVTFSSSG--KYMASASRDKTVRIWVPTVTGSTGMF--KAHSQTVRSVQFSS 115
+GH +++ +T +G Y+ S S D + W + TG F K H+ V +
Sbjct: 317 KGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYW-DSETGENDSFAGKGHTNQVSRMTVDE 375
Query: 116 DGSKIITASDDKVVKLWSTHKHKFISSFVGHTN-WVRCARMSNDGSIIASCSDDKSTKLW 174
G ++I+ S D V+ S + V + +C + G + C +
Sbjct: 376 SG-QLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQI---VL 431
Query: 175 NLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSI--HN 231
D +C D G+ + A HP G VA+ GNV+LY I L +
Sbjct: 432 LKDQRKCFSI--DNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAK 489
Query: 232 EAVTQVAIHPSGSYILTASKDGKMKILDLLEGH 264
VT VA G+++ + + + +G+
Sbjct: 490 GPVTDVAYSHDGAFLAVCDASKVVTVFSVADGY 522
>AF020056-1|AAD05044.1| 606|Homo sapiens WDR1 protein protein.
Length = 606
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/342 (21%), Positives = 142/342 (41%), Gaps = 22/342 (6%)
Query: 11 PCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL--RGTMRSYRFQGHDEAVMD 68
P L H + + Y P+ IA+ + + +WD + + Y +Q + D
Sbjct: 48 PALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKD 107
Query: 69 VTFSSSGKYMA--SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFS-SDGSKIITASD 125
+ ++ K +A R+K +++ S G H++ + SV S ++ T SD
Sbjct: 108 IAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSD 167
Query: 126 DKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
D + KF + H+ +V C R S DG+ A+ S D +++ +GE +
Sbjct: 168 DNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCAL 227
Query: 186 KDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV-TQVAIHP 241
K H G++ ++W P ++ A+ K++D+ +++V + + + + Q+
Sbjct: 228 GGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLW 287
Query: 242 SGSYILTASKDGKMKILDLLE-GHPIFTLSGHNGPVNAVNFSPTG--DTFSSAGDDKLVF 298
++L+ S G + LD P+ + GH+ + + G S D +
Sbjct: 288 QKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHIN 347
Query: 299 IWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQI 340
W SE+ EN+ G+ H + T+ E+GQ+
Sbjct: 348 YW-------DSETGENDS---FAGKGHTNQVSRMTVDESGQL 379
Score = 61.7 bits (143), Expect = 1e-08
Identities = 62/295 (21%), Positives = 121/295 (41%), Gaps = 16/295 (5%)
Query: 60 QGHDEAVMDVTFSSSG--KYMASASRDKTVRIWVPTVTGSTGMF--KAHSQTVRSVQFSS 115
+GH +++ +T +G Y+ S S D + W + TG F K H+ V +
Sbjct: 317 KGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYW-DSETGENDSFAGKGHTNQVSRMTVDE 375
Query: 116 DGSKIITASDDKVVKLWSTHKHKFISSFVGHTN-WVRCARMSNDGSIIASCSDDKSTKLW 174
G ++I+ S D V+ S + V + +C + G + C +
Sbjct: 376 SG-QLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQI---VL 431
Query: 175 NLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
D +C D G+ + A HP G VA+ GNV+LY I L +
Sbjct: 432 LKDQRKCFSI--DNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAK 489
Query: 234 --VTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSS 290
VT VA G+++ + + + +G+ + GH+ + + +SP + F+S
Sbjct: 490 GPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFAS 549
Query: 291 AGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQIQDVNI 345
G D +V++W + + + ++ + ++ L E + T + + +++ I
Sbjct: 550 GGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTI 604
>AB010427-1|BAA31855.2| 606|Homo sapiens NORI-1 protein.
Length = 606
Score = 87.0 bits (206), Expect = 3e-16
Identities = 72/342 (21%), Positives = 142/342 (41%), Gaps = 22/342 (6%)
Query: 11 PCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL--RGTMRSYRFQGHDEAVMD 68
P L H + + Y P+ IA+ + + +WD + + Y +Q + D
Sbjct: 48 PALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKD 107
Query: 69 VTFSSSGKYMA--SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFS-SDGSKIITASD 125
+ ++ K +A R+K +++ S G H++ + SV S ++ T SD
Sbjct: 108 IAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSD 167
Query: 126 DKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
D + KF + H+ +V C R S DG+ A+ S D +++ +GE +
Sbjct: 168 DNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCAL 227
Query: 186 KDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV-TQVAIHP 241
K H G++ ++W P ++ A+ K++D+ +++V + + + + Q+
Sbjct: 228 GGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLW 287
Query: 242 SGSYILTASKDGKMKILDLLE-GHPIFTLSGHNGPVNAVNFSPTG--DTFSSAGDDKLVF 298
++L+ S G + LD P+ + GH+ + + G S D +
Sbjct: 288 QKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHIN 347
Query: 299 IWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQI 340
W SE+ EN+ G+ H + T+ E+GQ+
Sbjct: 348 YW-------DSETGENDS---FAGKGHTNQVSRMTVDESGQL 379
Score = 61.7 bits (143), Expect = 1e-08
Identities = 62/295 (21%), Positives = 121/295 (41%), Gaps = 16/295 (5%)
Query: 60 QGHDEAVMDVTFSSSG--KYMASASRDKTVRIWVPTVTGSTGMF--KAHSQTVRSVQFSS 115
+GH +++ +T +G Y+ S S D + W + TG F K H+ V +
Sbjct: 317 KGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYW-DSETGENDSFAGKGHTNQVSRMTVDE 375
Query: 116 DGSKIITASDDKVVKLWSTHKHKFISSFVGHTN-WVRCARMSNDGSIIASCSDDKSTKLW 174
G ++I+ S D V+ S + V + +C + G + C +
Sbjct: 376 SG-QLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQI---VL 431
Query: 175 NLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
D +C D G+ + A HP G VA+ GNV+LY I L +
Sbjct: 432 LKDQRKCFSI--DNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAK 489
Query: 234 --VTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSS 290
VT VA G+++ + + + +G+ + GH+ + + +SP + F+S
Sbjct: 490 GPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFAS 549
Query: 291 AGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQIQDVNI 345
G D +V++W + + + ++ + ++ L E + T + + +++ I
Sbjct: 550 GGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTI 604
>BC000201-1|AAH00201.1| 606|Homo sapiens WD repeat domain 1
protein.
Length = 606
Score = 86.6 bits (205), Expect = 4e-16
Identities = 72/342 (21%), Positives = 142/342 (41%), Gaps = 22/342 (6%)
Query: 11 PCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL--RGTMRSYRFQGHDEAVMD 68
P L H + + Y P+ IA+ + + +WD + + Y +Q + D
Sbjct: 48 PALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKD 107
Query: 69 VTFSSSGKYMA--SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFS-SDGSKIITASD 125
+ ++ K +A R+K +++ S G H++ + SV S ++ T SD
Sbjct: 108 IAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSD 167
Query: 126 DKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
D + KF + H+ +V C R S DG+ A+ S D +++ +GE +
Sbjct: 168 DNCAAFFEGPPFKFKFTVGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCAL 227
Query: 186 KDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV-TQVAIHP 241
K H G++ ++W P ++ A+ K++D+ +++V + + + + Q+
Sbjct: 228 GGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLW 287
Query: 242 SGSYILTASKDGKMKILDLLE-GHPIFTLSGHNGPVNAVNFSPTG--DTFSSAGDDKLVF 298
++L+ S G + LD P+ + GH+ + + G S D +
Sbjct: 288 QKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHIN 347
Query: 299 IWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQI 340
W SE+ EN+ G+ H + T+ E+GQ+
Sbjct: 348 YW-------DSETGENDS---FAGKGHTNQVSRMTVDESGQL 379
Score = 61.7 bits (143), Expect = 1e-08
Identities = 62/295 (21%), Positives = 121/295 (41%), Gaps = 16/295 (5%)
Query: 60 QGHDEAVMDVTFSSSG--KYMASASRDKTVRIWVPTVTGSTGMF--KAHSQTVRSVQFSS 115
+GH +++ +T +G Y+ S S D + W + TG F K H+ V +
Sbjct: 317 KGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYW-DSETGENDSFAGKGHTNQVSRMTVDE 375
Query: 116 DGSKIITASDDKVVKLWSTHKHKFISSFVGHTN-WVRCARMSNDGSIIASCSDDKSTKLW 174
G ++I+ S D V+ S + V + +C + G + C +
Sbjct: 376 SG-QLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQI---VL 431
Query: 175 NLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
D +C D G+ + A HP G VA+ GNV+LY I L +
Sbjct: 432 LKDQRKCFSI--DNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAK 489
Query: 234 --VTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSS 290
VT VA G+++ + + + +G+ + GH+ + + +SP + F+S
Sbjct: 490 GPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFAS 549
Query: 291 AGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQIQDVNI 345
G D +V++W + + + ++ + ++ L E + T + + +++ I
Sbjct: 550 GGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTI 604
>AK222897-1|BAD96617.1| 606|Homo sapiens WD repeat-containing
protein 1 isoform 1 variant protein.
Length = 606
Score = 86.6 bits (205), Expect = 4e-16
Identities = 72/342 (21%), Positives = 142/342 (41%), Gaps = 22/342 (6%)
Query: 11 PCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL--RGTMRSYRFQGHDEAVMD 68
P L H + + Y P+ IA+ + + +WD + + Y +Q + D
Sbjct: 48 PALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKD 107
Query: 69 VTFSSSGKYMA--SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFS-SDGSKIITASD 125
+ ++ K +A R+K +++ S G H++ + SV S ++ T SD
Sbjct: 108 IAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSD 167
Query: 126 DKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
D + KF + H+ +V C R S DG+ A+ S D +++ +GE +
Sbjct: 168 DNCAAFFEGPPFKFKFTVGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCAL 227
Query: 186 KDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV-TQVAIHP 241
K H G++ ++W P ++ A+ K++D+ +++V + + + + Q+
Sbjct: 228 GGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLW 287
Query: 242 SGSYILTASKDGKMKILDLLE-GHPIFTLSGHNGPVNAVNFSPTG--DTFSSAGDDKLVF 298
++L+ S G + LD P+ + GH+ + + G S D +
Sbjct: 288 QKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHIN 347
Query: 299 IWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQI 340
W SE+ EN+ G+ H + T+ E+GQ+
Sbjct: 348 YW-------DSETGENDS---FAGKGHTNQVSRMTVDESGQL 379
Score = 61.7 bits (143), Expect = 1e-08
Identities = 62/295 (21%), Positives = 121/295 (41%), Gaps = 16/295 (5%)
Query: 60 QGHDEAVMDVTFSSSG--KYMASASRDKTVRIWVPTVTGSTGMF--KAHSQTVRSVQFSS 115
+GH +++ +T +G Y+ S S D + W + TG F K H+ V +
Sbjct: 317 KGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYW-DSETGENDSFAGKGHTNQVSRMTVDE 375
Query: 116 DGSKIITASDDKVVKLWSTHKHKFISSFVGHTN-WVRCARMSNDGSIIASCSDDKSTKLW 174
G ++I+ S D V+ S + V + +C + G + C +
Sbjct: 376 SG-QLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQI---VL 431
Query: 175 NLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
D +C D G+ + A HP G VA+ GNV+LY I L +
Sbjct: 432 LKDQRKCFSI--DNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAK 489
Query: 234 --VTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSS 290
VT VA G+++ + + + +G+ + GH+ + + +SP + F+S
Sbjct: 490 GPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFAS 549
Query: 291 AGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQIQDVNI 345
G D +V++W + + + ++ + ++ L E + T + + +++ I
Sbjct: 550 GGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTI 604
>AK222764-1|BAD96484.1| 606|Homo sapiens WD repeat-containing
protein 1 isoform 1 variant protein.
Length = 606
Score = 86.6 bits (205), Expect = 4e-16
Identities = 72/342 (21%), Positives = 142/342 (41%), Gaps = 22/342 (6%)
Query: 11 PCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL--RGTMRSYRFQGHDEAVMD 68
P L H + + Y P+ IA+ + + +WD + + Y +Q + D
Sbjct: 48 PALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKD 107
Query: 69 VTFSSSGKYMA--SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFS-SDGSKIITASD 125
+ ++ K +A R+K +++ S G H++ + SV S ++ T SD
Sbjct: 108 IAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSD 167
Query: 126 DKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
D + KF + H+ +V C R S DG+ A+ S D +++ +GE +
Sbjct: 168 DNCAAFFEGPPFKFKFTVGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCAL 227
Query: 186 KDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV-TQVAIHP 241
K H G++ ++W P ++ A+ K++D+ +++V + + + + Q+
Sbjct: 228 GGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLW 287
Query: 242 SGSYILTASKDGKMKILDLLE-GHPIFTLSGHNGPVNAVNFSPTG--DTFSSAGDDKLVF 298
++L+ S G + LD P+ + GH+ + + G S D +
Sbjct: 288 QKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHIN 347
Query: 299 IWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQI 340
W SE+ EN+ G+ H + T+ E+GQ+
Sbjct: 348 YW-------DSETGENDS---FAGKGHTNQVSRMTVDESGQL 379
Score = 61.7 bits (143), Expect = 1e-08
Identities = 62/295 (21%), Positives = 121/295 (41%), Gaps = 16/295 (5%)
Query: 60 QGHDEAVMDVTFSSSG--KYMASASRDKTVRIWVPTVTGSTGMF--KAHSQTVRSVQFSS 115
+GH +++ +T +G Y+ S S D + W + TG F K H+ V +
Sbjct: 317 KGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYW-DSETGENDSFAGKGHTNQVSRMTVDE 375
Query: 116 DGSKIITASDDKVVKLWSTHKHKFISSFVGHTN-WVRCARMSNDGSIIASCSDDKSTKLW 174
G ++I+ S D V+ S + V + +C + G + C +
Sbjct: 376 SG-QLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQI---VL 431
Query: 175 NLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
D +C D G+ + A HP G VA+ GNV+LY I L +
Sbjct: 432 LKDQRKCFSI--DNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAK 489
Query: 234 --VTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSS 290
VT VA G+++ + + + +G+ + GH+ + + +SP + F+S
Sbjct: 490 GPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFAS 549
Query: 291 AGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQIQDVNI 345
G D +V++W + + + ++ + ++ L E + T + + +++ I
Sbjct: 550 GGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLFTTSHDASVKEWTI 604
>AB209746-1|BAD92983.1| 624|Homo sapiens WD repeat-containing
protein 1 isoform 1 variant protein.
Length = 624
Score = 86.6 bits (205), Expect = 4e-16
Identities = 72/342 (21%), Positives = 142/342 (41%), Gaps = 22/342 (6%)
Query: 11 PCLKKQLKGHKNAITALYYNPNDQQIATSSLDNSVLLWDL--RGTMRSYRFQGHDEAVMD 68
P L H + + Y P+ IA+ + + +WD + + Y +Q + D
Sbjct: 66 PALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFAGKIKD 125
Query: 69 VTFSSSGKYMA--SASRDKTVRIWVPTVTGSTGMFKAHSQTVRSVQFS-SDGSKIITASD 125
+ ++ K +A R+K +++ S G H++ + SV S ++ T SD
Sbjct: 126 IAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSD 185
Query: 126 DKVVKLWSTHKHKFISSFVGHTNWVRCARMSNDGSIIASCSDDKSTKLWNLDSGECIHTY 185
D + KF + H+ +V C R S DG+ A+ S D +++ +GE +
Sbjct: 186 DNCAAFFEGPPFKFKFTVGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCAL 245
Query: 186 KDLKGH--GLH-LAWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEAV-TQVAIHP 241
K H G++ ++W P ++ A+ K++D+ +++V + + + + Q+
Sbjct: 246 GGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGSTVLDQQLGCLW 305
Query: 242 SGSYILTASKDGKMKILDLLE-GHPIFTLSGHNGPVNAVNFSPTG--DTFSSAGDDKLVF 298
++L+ S G + LD P+ + GH+ + + G S D +
Sbjct: 306 QKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGKSYIYSGSHDGHIN 365
Query: 299 IWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQI 340
W SE+ EN+ G+ H + T+ E+GQ+
Sbjct: 366 YW-------DSETGENDS---FAGKGHTNQVSRMTVDESGQL 397
Score = 61.7 bits (143), Expect = 1e-08
Identities = 62/295 (21%), Positives = 121/295 (41%), Gaps = 16/295 (5%)
Query: 60 QGHDEAVMDVTFSSSG--KYMASASRDKTVRIWVPTVTGSTGMF--KAHSQTVRSVQFSS 115
+GH +++ +T +G Y+ S S D + W + TG F K H+ V +
Sbjct: 335 KGHSKSIQCLTVHKNGGKSYIYSGSHDGHINYW-DSETGENDSFAGKGHTNQVSRMTVDE 393
Query: 116 DGSKIITASDDKVVKLWSTHKHKFISSFVGHTN-WVRCARMSNDGSIIASCSDDKSTKLW 174
G ++I+ S D V+ S + V + +C + G + C +
Sbjct: 394 SG-QLISCSMDDTVRYTSLMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQI---VL 449
Query: 175 NLDSGECIHTYKDLKGHGLHL-AWHPSGCYVAVATSHGNVKLYDIRTHNLVQYYSIHNEA 233
D +C D G+ + A HP G VA+ GNV+LY I L +
Sbjct: 450 LKDQRKCFSI--DNPGYEPEVVAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAK 507
Query: 234 --VTQVAIHPSGSYILTASKDGKMKILDLLEGHPIFTLS-GHNGPVNAVNFSPTGDTFSS 290
VT VA G+++ + + + +G+ + GH+ + + +SP + F+S
Sbjct: 508 GPVTDVAYSHDGAFLAVCDASKVVTVFSVADGYSENNVFYGHHAKIVCLAWSPDNEHFAS 567
Query: 291 AGDDKLVFIWKTNFTDLSSESKENEGQNMITGQRHLTEEGIDTITENGQIQDVNI 345
G D +V++W + + + ++ + ++ L E + T + + +++ I
Sbjct: 568 GGMDMMVYVWTLSDPETRVKIQDAHRLHHVSSLAWLDEHTLVTTSHDASVKEWTI 622
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.313 0.130 0.382
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 145,874,926
Number of Sequences: 224733
Number of extensions: 6353854
Number of successful extensions: 28521
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 843
Number of HSP's successfully gapped in prelim test: 494
Number of HSP's that attempted gapping in prelim test: 15466
Number of HSP's gapped (non-prelim): 7382
length of query: 961
length of database: 73,234,838
effective HSP length: 97
effective length of query: 864
effective length of database: 51,435,737
effective search space: 44440476768
effective search space used: 44440476768
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.9 bits)
S2: 70 (32.3 bits)
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