BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001035-TA|BGIBMGA001035-PA|IPR000644|CBS, IPR001093|IMP dehydrogenase/GMP reductase, IPR005990|IMP dehydrogenase (512 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_P20839 Cluster: Inosine-5'-monophosphate dehydrogenase ... 739 0.0 UniRef50_P12268 Cluster: Inosine-5'-monophosphate dehydrogenase ... 725 0.0 UniRef50_P21620 Cluster: Inosine-5'-monophosphate dehydrogenase;... 516 e-145 UniRef50_O96387 Cluster: Inosine-5'-monophosphate dehydrogenase;... 490 e-137 UniRef50_Q01F10 Cluster: IpdH inosine 5'-phosphate dehydrogenase... 481 e-134 UniRef50_Q4VRV8 Cluster: Inosine 5'monophosphate dehydrogenase; ... 481 e-134 UniRef50_Q4UCL4 Cluster: Inosine-5'-monophosphate dehydrogenase,... 472 e-131 UniRef50_P47996 Cluster: Inosine-5'-monophosphate dehydrogenase;... 434 e-120 UniRef50_A7QMJ8 Cluster: Chromosome chr19 scaffold_126, whole ge... 427 e-118 UniRef50_Q4SBU2 Cluster: Chromosome 19 SCAF14664, whole genome s... 419 e-115 UniRef50_A6R4D7 Cluster: Inosine-5'-monophosphate dehydrogenase;... 383 e-105 UniRef50_O67820 Cluster: Inosine-5'-monophosphate dehydrogenase;... 375 e-102 UniRef50_Q39F71 Cluster: IMP dehydrogenase; n=31; Proteobacteria... 357 4e-97 UniRef50_Q49729 Cluster: Inosine-5'-monophosphate dehydrogenase;... 346 7e-94 UniRef50_Q9RT87 Cluster: Inosine-5`-monophosphate dehydrogenase;... 331 2e-89 UniRef50_A7DPR0 Cluster: Inosine-5'-monophosphate dehydrogenase;... 331 2e-89 UniRef50_P0ADG9 Cluster: Inosine-5'-monophosphate dehydrogenase;... 325 1e-87 UniRef50_Q59011 Cluster: Inosine-5'-monophosphate dehydrogenase;... 313 8e-84 UniRef50_A6DTA2 Cluster: Inosine-5'-monophosphate dehydrogenase;... 305 1e-81 UniRef50_Q4QEB3 Cluster: Inosine-5'-monophosphate dehydrogenase;... 294 3e-78 UniRef50_Q4PBE7 Cluster: Putative uncharacterized protein; n=2; ... 281 2e-74 UniRef50_Q0DN24 Cluster: Os03g0780500 protein; n=7; Magnoliophyt... 265 2e-69 UniRef50_A7CYS7 Cluster: Malate dehydrogenase precursor; n=1; Op... 256 1e-66 UniRef50_Q8EW89 Cluster: Inosine-5'-monophosphate dehydrogenase;... 252 2e-65 UniRef50_P50097 Cluster: Inosine-5'-monophosphate dehydrogenase;... 240 7e-62 UniRef50_Q08MB8 Cluster: Inosine-5'-monophosphate dehydrogenase;... 223 9e-57 UniRef50_UPI00015B43E8 Cluster: PREDICTED: similar to GA14756-PA... 218 2e-55 UniRef50_P49058 Cluster: Inosine-5'-monophosphate dehydrogenase;... 205 2e-51 UniRef50_Q74LZ0 Cluster: Inosine-5-monophosphate dehydrogenase; ... 189 1e-46 UniRef50_P65172 Cluster: Uncharacterized oxidoreductase Rv1843c/... 170 9e-41 UniRef50_A3H9U2 Cluster: IMP dehydrogenase; n=1; Caldivirga maqu... 167 5e-40 UniRef50_Q6MM64 Cluster: Inosine-5-monophosphate dehydrogenase; ... 164 4e-39 UniRef50_A1RZ33 Cluster: GMP reductase; n=1; Thermofilum pendens... 151 3e-35 UniRef50_Q5V6J1 Cluster: Inosine-5'-monophosphate dehydrogenase;... 149 2e-34 UniRef50_Q1IAJ4 Cluster: Putative inosine-5'-monophosphate dehyd... 142 2e-32 UniRef50_Q2JC64 Cluster: GMP reductase; n=2; Bacteria|Rep: GMP r... 140 8e-32 UniRef50_Q9P2T1 Cluster: GMP reductase 2; n=169; cellular organi... 124 6e-27 UniRef50_P60565 Cluster: GMP reductase; n=111; root|Rep: GMP red... 121 5e-26 UniRef50_Q9YBU2 Cluster: Inosine-5'-monophosphate dehydrogenase;... 119 2e-25 UniRef50_Q5ZRN7 Cluster: Inosine 5'-monophosphate dehydrogenase;... 116 1e-24 UniRef50_A4GHK1 Cluster: Guanosine monophosphate reductase; n=1;... 105 4e-21 UniRef50_Q7NTY1 Cluster: GMP reductase; n=1; Chromobacterium vio... 101 3e-20 UniRef50_Q4S0S1 Cluster: Chromosome undetermined SCAF14779, whol... 99 3e-19 UniRef50_Q4X988 Cluster: Putative uncharacterized protein; n=6; ... 97 7e-19 UniRef50_Q4S0S8 Cluster: Chromosome undetermined SCAF14779, whol... 97 1e-18 UniRef50_Q0PQW0 Cluster: Putative inosine-5'-monophosphate dehyd... 95 4e-18 UniRef50_Q4UGU3 Cluster: Gmp reductase, putative; n=3; Piroplasm... 93 2e-17 UniRef50_Q2JL45 Cluster: IMP dehydrogenase family protein; n=43;... 84 7e-15 UniRef50_Q5RGU9 Cluster: Novel protein similar to vertebrate IMP... 77 8e-13 UniRef50_Q7VQ71 Cluster: GuaB gene for inosine 5-monophosphase d... 74 1e-11 UniRef50_Q4T162 Cluster: Chromosome 21 SCAF10714, whole genome s... 71 7e-11 UniRef50_Q8EUA0 Cluster: Guanosine 5'-monophosphate oxidoreducta... 71 7e-11 UniRef50_A1SMV5 Cluster: IMP dehydrogenase family protein; n=7; ... 70 2e-10 UniRef50_Q03YG3 Cluster: IMP dehydrogenase/GMP reductase; n=1; L... 69 3e-10 UniRef50_P74477 Cluster: Chloride channel protein; n=3; Chroococ... 66 3e-09 UniRef50_A6Y440 Cluster: GMP reductase; n=1; Vibrio cholerae RC3... 64 6e-09 UniRef50_P65170 Cluster: Uncharacterized oxidoreductase Rv3410c/... 64 6e-09 UniRef50_Q57647 Cluster: Uncharacterized protein MJ0188; n=6; Me... 63 1e-08 UniRef50_Q0S3A9 Cluster: Possible IMP dehydrogenase/GMP reductas... 63 2e-08 UniRef50_O27343 Cluster: Inosine-5'-monophosphate dehydrogenase ... 62 3e-08 UniRef50_O29009 Cluster: Inosine monophosphate dehydrogenase, pu... 57 1e-06 UniRef50_O28857 Cluster: Chloride channel, putative; n=2; Euryar... 56 2e-06 UniRef50_Q191T3 Cluster: Polynucleotide adenylyltransferase regi... 56 3e-06 UniRef50_O26907 Cluster: Sporulation protein IVFB related protei... 56 3e-06 UniRef50_Q2NEF3 Cluster: Putative uncharacterized protein; n=1; ... 54 7e-06 UniRef50_Q97F91 Cluster: Proline/glycine betaine ABC-type transp... 54 1e-05 UniRef50_Q02B15 Cluster: Putative signal-transduction protein wi... 54 1e-05 UniRef50_Q64C69 Cluster: Chloride channel; n=1; uncultured archa... 54 1e-05 UniRef50_O27290 Cluster: Inosine-5'-monophosphate dehydrogenase ... 53 2e-05 UniRef50_Q4TGB6 Cluster: Chromosome undetermined SCAF3807, whole... 53 2e-05 UniRef50_Q9HRK9 Cluster: Inosine-5'-monophosphate dehydrogenase;... 52 4e-05 UniRef50_Q2ACT2 Cluster: CBS:Phosphoesterase, RecJ-like:Polynucl... 52 5e-05 UniRef50_Q3AAR6 Cluster: PolyA polymerase family protein; n=1; C... 51 6e-05 UniRef50_A7HLG0 Cluster: Polynucleotide adenylyltransferase regi... 51 8e-05 UniRef50_A1HSL2 Cluster: Putative signal transduction protein wi... 51 8e-05 UniRef50_A6TR64 Cluster: Polynucleotide adenylyltransferase regi... 50 1e-04 UniRef50_A4J3L2 Cluster: Polynucleotide adenylyltransferase regi... 50 1e-04 UniRef50_Q31MV1 Cluster: CBS; n=3; Synechococcus elongatus|Rep: ... 50 1e-04 UniRef50_Q58629 Cluster: Uncharacterized protein MJ1232; n=6; Me... 50 1e-04 UniRef50_A7HD42 Cluster: Putative signal transduction protein wi... 50 2e-04 UniRef50_Q3E1R1 Cluster: CBS; n=3; Bacteria|Rep: CBS - Chlorofle... 49 3e-04 UniRef50_Q2NBF2 Cluster: CBS; n=3; Bacteria|Rep: CBS - Erythroba... 49 3e-04 UniRef50_Q898U3 Cluster: Inosine-5-monophosphate dehydrogenase r... 49 3e-04 UniRef50_Q8DLH3 Cluster: Tll0519 protein; n=4; Cyanobacteria|Rep... 48 4e-04 UniRef50_O66749 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04 UniRef50_A7RLX0 Cluster: Predicted protein; n=1; Nematostella ve... 48 4e-04 UniRef50_UPI00015BB20C Cluster: putative signal transduction pro... 48 8e-04 UniRef50_Q2JHW1 Cluster: PolyA polymerase family protein; n=3; S... 48 8e-04 UniRef50_Q8TWX4 Cluster: Prdicted regulatory protein consisting ... 48 8e-04 UniRef50_Q8R911 Cluster: CBS domains; n=3; Thermoanaerobacter|Re... 47 0.001 UniRef50_Q6Q303 Cluster: IMP dehydrogenase; n=1; Synechococcus s... 47 0.001 UniRef50_A0LGS9 Cluster: CBS domain containing membrane protein;... 47 0.001 UniRef50_Q96YR0 Cluster: Putative uncharacterized protein ST2113... 47 0.001 UniRef50_Q9X175 Cluster: Inosine-5-monophosphate dehydrogenase-r... 46 0.002 UniRef50_A5IN38 Cluster: CBS domain containing protein; n=2; The... 46 0.002 UniRef50_Q2ACR8 Cluster: CBS; n=1; Halothermothrix orenii H 168|... 46 0.002 UniRef50_A4M812 Cluster: Polynucleotide adenylyltransferase regi... 46 0.002 UniRef50_O29915 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002 UniRef50_Q7NVZ6 Cluster: Putative uncharacterized protein; n=3; ... 46 0.003 UniRef50_O26229 Cluster: Inosine-5'-monophosphate dehydrogenase ... 46 0.003 UniRef50_A3CWH1 Cluster: CBS domain containing protein; n=1; Met... 46 0.003 UniRef50_A7HCW1 Cluster: Putative signal-transduction protein wi... 45 0.004 UniRef50_A2ST08 Cluster: CBS domain containing protein; n=2; Met... 45 0.004 UniRef50_A6SYJ5 Cluster: Inosine-5'-monophosphate dehydrogenase;... 45 0.006 UniRef50_A5WFG6 Cluster: FMN-dependent alpha-hydroxy acid dehydr... 45 0.006 UniRef50_A1VAU2 Cluster: CBS domain containing protein; n=3; Des... 45 0.006 UniRef50_A7D0I7 Cluster: Peptidase M50; n=4; Halobacteriaceae|Re... 45 0.006 UniRef50_A0B5X6 Cluster: Putative signal-transduction protein wi... 45 0.006 UniRef50_Q67L31 Cluster: Glycine betaine/carnitine/choline ABC t... 44 0.007 UniRef50_Q3AFS5 Cluster: CBS/GGDEF domain protein; n=1; Carboxyd... 44 0.007 UniRef50_A5N386 Cluster: Putative uncharacterized protein; n=1; ... 44 0.007 UniRef50_A2SQ80 Cluster: CBS domain containing protein; n=4; Met... 44 0.007 UniRef50_A2BJ31 Cluster: Predicted transcriptional regulator; n=... 44 0.007 UniRef50_Q9WZH4 Cluster: TRNA nucleotidyl transferase-related pr... 44 0.010 UniRef50_A1CVD5 Cluster: 2-nitropropane dioxygenase family oxido... 44 0.010 UniRef50_A2BLX1 Cluster: Conserved archaeal protein; n=1; Hypert... 44 0.010 UniRef50_Q67NF3 Cluster: Putative poly A polymerase; n=1; Symbio... 44 0.013 UniRef50_A5V6U0 Cluster: FMN-dependent alpha-hydroxy acid dehydr... 44 0.013 UniRef50_A1HPJ0 Cluster: Sigma54 specific transcriptional regula... 44 0.013 UniRef50_Q0W4Y8 Cluster: Putative uncharacterized protein; n=1; ... 44 0.013 UniRef50_Q835K5 Cluster: CBS domain protein; n=6; Bacilli|Rep: C... 43 0.017 UniRef50_Q1IKU8 Cluster: 2-nitropropane dioxygenase, NPD; n=2; B... 43 0.017 UniRef50_A5D444 Cluster: Putative uncharacterized protein; n=1; ... 43 0.017 UniRef50_Q2H129 Cluster: Putative uncharacterized protein; n=1; ... 43 0.017 UniRef50_Q8TX12 Cluster: CBS-domain-containing protein; n=3; Eur... 43 0.017 UniRef50_Q57976 Cluster: Methylated protein MJ0556; n=2; Methano... 43 0.017 UniRef50_Q97M06 Cluster: Deoxyphosphogluconate aldolase; n=1; Cl... 43 0.022 UniRef50_Q5WEY2 Cluster: Putative uncharacterized protein; n=1; ... 43 0.022 UniRef50_Q3JCC7 Cluster: Peptidase M50; n=1; Nitrosococcus ocean... 43 0.022 UniRef50_Q0SD75 Cluster: Possible nitropropane dioxygenase; n=1;... 43 0.022 UniRef50_Q0SD94 Cluster: Possible 2-nitropropane dioxygenase; n=... 43 0.022 UniRef50_A4J1P0 Cluster: Putative signal-transduction protein wi... 43 0.022 UniRef50_Q2FT94 Cluster: Putative signal-transduction protein wi... 43 0.022 UniRef50_Q1D9V2 Cluster: CBS domain protein; n=1; Myxococcus xan... 42 0.029 UniRef50_A7HHL2 Cluster: Putative CBS domain and cyclic nucleoti... 42 0.039 UniRef50_A6GTG2 Cluster: Putative uncharacterized protein; n=1; ... 42 0.039 UniRef50_A0TVV5 Cluster: 2-nitropropane dioxygenase, NPD; n=1; B... 42 0.039 UniRef50_A0LL65 Cluster: Peptidase M50; n=2; Syntrophobacter fum... 42 0.039 UniRef50_Q8R7I7 Cluster: Putative N-acetylmannosamine-6-phosphat... 42 0.039 UniRef50_Q3ZXE7 Cluster: Metallopeptidase, M50 family; n=3; Deha... 42 0.051 UniRef50_Q3DF47 Cluster: AcuB family protein; n=27; Streptococcu... 42 0.051 UniRef50_Q24MB2 Cluster: Putative uncharacterized protein; n=2; ... 42 0.051 UniRef50_Q0PQV9 Cluster: Putative inosine-5'-monophosphate dehyd... 42 0.051 UniRef50_Q9YFL7 Cluster: Putative uncharacterized protein; n=1; ... 42 0.051 UniRef50_Q8PYN6 Cluster: Conserved protein; n=6; Euryarchaeota|R... 42 0.051 UniRef50_Q8PUG3 Cluster: Conserved protein; n=8; Euryarchaeota|R... 42 0.051 UniRef50_O27616 Cluster: Inosine-5'-monophosphate dehydrogenase ... 42 0.051 UniRef50_P54606 Cluster: Uncharacterized protein yhcV; n=6; Baci... 42 0.051 UniRef50_Q5LSF9 Cluster: Nucleotidyltransferase/CBS/cyclic nucle... 41 0.068 UniRef50_Q8VKG1 Cluster: FMN-dependent alpha-hydroxy acid dehydr... 41 0.068 UniRef50_Q1AXH4 Cluster: CBS domain containing membrane protein;... 41 0.068 UniRef50_A5UX62 Cluster: Polynucleotide adenylyltransferase regi... 41 0.068 UniRef50_A3W676 Cluster: Nucleotidyltransferase/CBS/cyclic nucle... 41 0.068 UniRef50_A0QGC0 Cluster: Oxidoreductase, 2-nitropropane dioxygen... 41 0.068 UniRef50_A0PYB8 Cluster: CBS domain containing protein; n=3; Clo... 41 0.068 UniRef50_A0G4J4 Cluster: 2-nitropropane dioxygenase, NPD; n=1; B... 41 0.068 UniRef50_O86223 Cluster: Putative uncharacterized protein HI0221... 41 0.068 UniRef50_Q3ZYM9 Cluster: 1-(5-phosphoribosyl)-5-[(5-phosphoribos... 41 0.068 UniRef50_Q98QF8 Cluster: MG2+ TRANSPORT PROTEIN; n=1; Mycoplasma... 41 0.090 UniRef50_Q74HC1 Cluster: Glycolate oxidase; n=8; Lactobacillacea... 41 0.090 UniRef50_Q9LUF7 Cluster: Emb|CAB86899.1; n=6; Magnoliophyta|Rep:... 41 0.090 UniRef50_Q3IUS4 Cluster: Probable metalloprotease/ CBS domain pr... 41 0.090 UniRef50_A2BJY0 Cluster: Voltage-gated chloride channel protein;... 41 0.090 UniRef50_Q58069 Cluster: Uncharacterized protein MJ0653; n=1; Me... 41 0.090 UniRef50_Q9RVN7 Cluster: Acetoin utilization protein, putative; ... 40 0.12 UniRef50_A4AAP3 Cluster: Acetoin utilization protein AcuB; n=1; ... 40 0.12 UniRef50_A3SFF5 Cluster: FMN-dependent alpha-hydroxy acid dehydr... 40 0.12 UniRef50_Q3SB86 Cluster: CBS domain protein; n=1; uncultured eur... 40 0.12 UniRef50_A7IAI3 Cluster: Putative signal transduction protein wi... 40 0.12 UniRef50_Q15XE0 Cluster: 2-nitropropane dioxygenase, NPD; n=9; P... 40 0.16 UniRef50_A6GD90 Cluster: Acetoin utilization protein AcuB; n=1; ... 40 0.16 UniRef50_A6CN21 Cluster: CBS domain protein; n=1; Bacillus sp. S... 40 0.16 UniRef50_Q01N18 Cluster: OSIGBa0147B06.5 protein; n=3; Oryza sat... 40 0.16 UniRef50_A7DSJ1 Cluster: Putative signal-transduction protein wi... 40 0.16 UniRef50_Q9CG58 Cluster: L-lactate oxidase; n=6; Bacteria|Rep: L... 40 0.21 UniRef50_Q62DY2 Cluster: FMN-dependent dehydrogenase; n=17; Prot... 40 0.21 UniRef50_Q2CIM8 Cluster: Alcohol dehydrogenase, zinc containing;... 40 0.21 UniRef50_Q1AXT4 Cluster: Inorganic diphosphatase; n=1; Rubrobact... 40 0.21 UniRef50_A5URS2 Cluster: CBS domain containing protein; n=2; Ros... 40 0.21 UniRef50_Q4PDX7 Cluster: Putative uncharacterized protein; n=1; ... 40 0.21 UniRef50_Q8TZ50 Cluster: CBS-domain-containing protein; n=1; Met... 40 0.21 UniRef50_O13965 Cluster: Meiotically up-regulated gene 70 protei... 40 0.21 UniRef50_Q7U851 Cluster: 1-(5-phosphoribosyl)-5-[(5-phosphoribos... 40 0.21 UniRef50_Q4US80 Cluster: 2-nitropropane dioxygenase; n=9; Proteo... 39 0.27 UniRef50_Q180W2 Cluster: Putative uncharacterized protein; n=1; ... 39 0.27 UniRef50_A6QB31 Cluster: 2-nitropropane dioxygenase; n=29; Bacte... 39 0.27 UniRef50_A3PVW7 Cluster: 2-nitropropane dioxygenase, NPD; n=8; C... 39 0.27 UniRef50_A1ZUR2 Cluster: CBS domain protein; n=2; Bacteroidetes|... 39 0.27 UniRef50_Q54H97 Cluster: Putative acetoin dehydrogenase; n=1; Di... 39 0.27 UniRef50_Q2RGX5 Cluster: Ferredoxin-dependent glutamate synthase... 39 0.36 UniRef50_Q08PS9 Cluster: CBS; n=1; Stigmatella aurantiaca DW4/3-... 39 0.36 UniRef50_A3M1P1 Cluster: Magnesium and cobalt efflux protein; n=... 39 0.36 UniRef50_A0HCZ3 Cluster: FMN-dependent alpha-hydroxy acid dehydr... 39 0.36 UniRef50_Q97U50 Cluster: Putative uncharacterized protein; n=1; ... 39 0.36 UniRef50_Q8TXY3 Cluster: CBS domain-containing protein; n=1; Met... 39 0.36 UniRef50_O26296 Cluster: Glutamate synthase (NADPH), alpha subun... 39 0.36 UniRef50_A5UM30 Cluster: IMP dehydrogenase related protein; n=1;... 39 0.36 UniRef50_A0B5X2 Cluster: CBS domain containing membrane protein;... 39 0.36 UniRef50_Q57837 Cluster: Putative zinc metalloprotease MJ0392; n... 39 0.36 UniRef50_Q9KGA2 Cluster: BH0210 protein; n=7; Bacillaceae|Rep: B... 38 0.48 UniRef50_Q8F624 Cluster: L-lactate dehydrogenase; n=4; Leptospir... 38 0.48 UniRef50_Q6AJC1 Cluster: Related to acetoin utilization protein;... 38 0.48 UniRef50_Q5QUI2 Cluster: Signaling protein with a cAMP-binding, ... 38 0.48 UniRef50_P74081 Cluster: PolyA polymerase; n=4; Cyanobacteria|Re... 38 0.48 UniRef50_Q3T556 Cluster: CBS domain-like protein; n=5; Bacteria|... 38 0.48 UniRef50_Q11EL1 Cluster: CBS domain containing protein; n=13; Pr... 38 0.48 UniRef50_A6LV86 Cluster: Sigma54 specific transcriptional regula... 38 0.48 UniRef50_A5URS3 Cluster: CBS domain containing protein; n=4; Chl... 38 0.48 UniRef50_A4M3K4 Cluster: CBS domain containing membrane protein;... 38 0.48 UniRef50_A3ZL92 Cluster: Putative uncharacterized protein; n=1; ... 38 0.48 UniRef50_O27702 Cluster: Glutamate synthase (NADPH), alpha subun... 38 0.48 UniRef50_A3CWH3 Cluster: CBS domain containing protein; n=1; Met... 38 0.48 UniRef50_Q97EU8 Cluster: CBS domain containing protein; n=1; Clo... 38 0.63 UniRef50_Q3J9M3 Cluster: CBS domain containing protein; n=1; Nit... 38 0.63 UniRef50_Q8GA65 Cluster: Putative FMN-dependent dehydrogenase; n... 38 0.63 UniRef50_Q3RE81 Cluster: 2-nitropropane dioxygenase, NPD precurs... 38 0.63 UniRef50_A4WYL0 Cluster: Putative uncharacterized protein; n=1; ... 38 0.63 UniRef50_A4M6L8 Cluster: 2-nitropropane dioxygenase, NPD; n=2; B... 38 0.63 UniRef50_A1IEP7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.63 UniRef50_A1I7E2 Cluster: 2-nitropropane dioxygenase, NPD; n=1; C... 38 0.63 UniRef50_O29411 Cluster: Inosine monophosphate dehydrogenase; n=... 38 0.63 UniRef50_Q58410 Cluster: Uncharacterized protein MJ1004; n=6; Me... 38 0.63 UniRef50_A3CTR9 Cluster: 1-(5-phosphoribosyl)-5-[(5-phosphoribos... 38 0.63 UniRef50_UPI00015BAEC4 Cluster: putative signal-transduction pro... 38 0.84 UniRef50_Q9K9P0 Cluster: BH2605 protein; n=6; Bacteria|Rep: BH26... 38 0.84 UniRef50_Q3WH73 Cluster: CBS domain; n=2; Frankia|Rep: CBS domai... 38 0.84 UniRef50_Q122S0 Cluster: 2-nitropropane dioxygenase, NPD; n=68; ... 38 0.84 UniRef50_Q0VMM0 Cluster: 2-nitropropane dioxygenase, putative; n... 38 0.84 UniRef50_Q0AHF1 Cluster: Putative signal-transduction protein wi... 38 0.84 UniRef50_A1SM43 Cluster: 2-nitropropane dioxygenase, NPD; n=1; N... 38 0.84 UniRef50_Q6C9A7 Cluster: Similar to sp|Q9WU19 Mus musculus Hydro... 38 0.84 UniRef50_Q6LXU6 Cluster: Putative uncharacterized protein; n=5; ... 38 0.84 UniRef50_Q4JBX5 Cluster: Conserved CBS domain protein; n=2; Sulf... 38 0.84 UniRef50_Q4JAS3 Cluster: Protein pcrB homolog; n=4; Sulfolobacea... 38 0.84 UniRef50_A4FVH7 Cluster: Hao1 protein; n=9; Deuterostomia|Rep: H... 37 1.1 UniRef50_Q9KDK7 Cluster: BH1205 protein; n=2; Bacillus|Rep: BH12... 37 1.1 UniRef50_Q98DX5 Cluster: Cysteine synthase; n=42; Bacteria|Rep: ... 37 1.1 UniRef50_Q98DF1 Cluster: Glycolate oxidase (S)-2-hydroxy-acid ox... 37 1.1 UniRef50_Q8NQY4 Cluster: Predicted signal-transduction protein c... 37 1.1 UniRef50_Q8DHZ1 Cluster: CBS domain protein; n=1; Synechococcus ... 37 1.1 UniRef50_Q8CXK9 Cluster: Glutamate synthase (NADPH) large (Alpha... 37 1.1 UniRef50_Q5LKQ6 Cluster: Oxidoreductase, 2-nitropropane dioxygen... 37 1.1 UniRef50_Q3A5H4 Cluster: Putative Fe-S oxidoreductase; n=1; Pelo... 37 1.1 UniRef50_Q21UP4 Cluster: Putative signal-transduction protein wi... 37 1.1 UniRef50_Q1Q2I4 Cluster: Putative uncharacterized protein; n=1; ... 37 1.1 UniRef50_Q1LK44 Cluster: 2-nitropropane dioxygenase, NPD; n=2; B... 37 1.1 UniRef50_A6CKR1 Cluster: Putative uncharacterized protein; n=1; ... 37 1.1 UniRef50_A5UUL3 Cluster: Thiamine-phosphate pyrophosphorylase; n... 37 1.1 UniRef50_O27292 Cluster: Inosine-5'-monophosphate dehydrogenase ... 37 1.1 UniRef50_P61411 Cluster: Putative thiamine-phosphate pyrophospho... 37 1.1 UniRef50_Q3AYT2 Cluster: 1-(5-phosphoribosyl)-5-[(5-phosphoribos... 37 1.1 UniRef50_O87392 Cluster: Glutamate synthase large subunit-like p... 37 1.1 UniRef50_UPI0000E45D53 Cluster: PREDICTED: similar to Hao1 prote... 37 1.5 UniRef50_Q89DV5 Cluster: Blr7332 protein; n=2; Proteobacteria|Re... 37 1.5 UniRef50_Q18QE4 Cluster: Ferredoxin-dependent glutamate synthase... 37 1.5 UniRef50_Q0RJ56 Cluster: Putative Glycolate oxidase; n=1; Franki... 37 1.5 UniRef50_A0YE28 Cluster: CBS domain containing membrane protein;... 37 1.5 UniRef50_A0WCB8 Cluster: Twin-arginine translocation pathway sig... 37 1.5 UniRef50_Q3IUC7 Cluster: CBS domain protein 2; n=4; Halobacteria... 37 1.5 UniRef50_Q8YSG5 Cluster: Sensor protein; n=3; Cyanobacteria|Rep:... 36 1.9 UniRef50_Q7MZC1 Cluster: Similar to lactate oxidase; n=1; Photor... 36 1.9 UniRef50_Q6ASD5 Cluster: Related to poly(A) polymerase; n=1; Des... 36 1.9 UniRef50_Q5WGH8 Cluster: Proline/glycine betaine ABC transporter... 36 1.9 UniRef50_Q5HNK0 Cluster: CBS domain protein; n=16; Staphylococcu... 36 1.9 UniRef50_Q3SPZ7 Cluster: Histidine biosynthesis; n=1; Nitrobacte... 36 1.9 UniRef50_Q2RL38 Cluster: Diguanylate cyclase; n=2; Clostridia|Re... 36 1.9 UniRef50_Q2IQL5 Cluster: Putative transcriptional regulator, XRE... 36 1.9 UniRef50_Q1CVT6 Cluster: CBS domain protein; n=1; Myxococcus xan... 36 1.9 UniRef50_A5VE75 Cluster: FMN-dependent alpha-hydroxy acid dehydr... 36 1.9 UniRef50_A1W7G3 Cluster: CBS domain containing protein; n=3; Com... 36 1.9 UniRef50_A0NXC3 Cluster: 2-nitropropane dioxygenase, NPD; n=1; S... 36 1.9 UniRef50_Q01E22 Cluster: COG2070: Dioxygenases related to 2-nitr... 36 1.9 UniRef50_O27073 Cluster: Inosine-5'-monophosphate dehydrogenase ... 36 1.9 UniRef50_Q0W6W1 Cluster: Predicted metalloprotease; n=1; uncultu... 36 1.9 UniRef50_Q0W3K0 Cluster: Conserved hypothetical CBS domain prote... 36 1.9 UniRef50_Q0W3J9 Cluster: Conserved hypothetical CBS domain prote... 36 1.9 UniRef50_P50100 Cluster: Uncharacterized protein MK0525; n=1; Me... 36 1.9 UniRef50_Q58799 Cluster: Uncharacterized protein MJ1404; n=7; Ar... 36 1.9 UniRef50_P20932 Cluster: (S)-mandelate dehydrogenase (EC 1.1.99.... 36 1.9 UniRef50_UPI000023D501 Cluster: hypothetical protein FG00145.1; ... 36 2.6 UniRef50_Q7V9S3 Cluster: L-lactate dehydrogenase (FMN-dependent)... 36 2.6 UniRef50_Q6ML62 Cluster: 2-nitropropane dioxygenase; n=1; Bdello... 36 2.6 UniRef50_Q39UG3 Cluster: CBS domain containing membrane protein;... 36 2.6 UniRef50_Q41GS5 Cluster: CBS; n=1; Exiguobacterium sibiricum 255... 36 2.6 UniRef50_Q1Q3V8 Cluster: Putative uncharacterized protein; n=1; ... 36 2.6 UniRef50_Q1AXV7 Cluster: Putative signal transduction protein wi... 36 2.6 UniRef50_A0LCY3 Cluster: Putative signal-transduction protein wi... 36 2.6 UniRef50_A0HLX4 Cluster: 2-nitropropane dioxygenase, NPD; n=2; C... 36 2.6 UniRef50_Q97AJ9 Cluster: Inosine-5-monophosphate dehydrogenase; ... 36 2.6 UniRef50_O28109 Cluster: 2-nitropropane dioxygenase; n=1; Archae... 36 2.6 UniRef50_A3CWH2 Cluster: CBS domain containing protein; n=2; Met... 36 2.6 UniRef50_P35500-9 Cluster: Isoform exond of P35500 ; n=24; Arthr... 36 3.4 UniRef50_Q8DKD5 Cluster: Tlr0924 protein; n=1; Synechococcus elo... 36 3.4 UniRef50_Q89K26 Cluster: Bll5092 protein; n=3; Bradyrhizobium|Re... 36 3.4 UniRef50_Q6N8G2 Cluster: Possible 2-nitropropane dioxygenase; n=... 36 3.4 UniRef50_Q6MJ98 Cluster: Putative inosine-5'-monophosphate dehyd... 36 3.4 UniRef50_Q6AN54 Cluster: Related to two-component system respons... 36 3.4 UniRef50_Q2SLE2 Cluster: L-lactate dehydrogenase (FMN-dependent)... 36 3.4 UniRef50_Q2RZU3 Cluster: CBS domain pair protein; n=2; Salinibac... 36 3.4 UniRef50_Q6SH70 Cluster: Oxidoreductase, 2-nitropropane dioxygen... 36 3.4 UniRef50_Q4AIJ6 Cluster: Geranylgeranylglyceryl phosphate syntha... 36 3.4 UniRef50_Q3W684 Cluster: FMN-dependent alpha-hydroxy acid dehydr... 36 3.4 UniRef50_Q1D9J4 Cluster: Tetratricopeptide repeat protein; n=1; ... 36 3.4 UniRef50_Q18SL5 Cluster: Ferredoxin-dependent glutamate synthase... 36 3.4 UniRef50_Q0K474 Cluster: 2-Nitropropane dioxygenase; n=3; Cupria... 36 3.4 UniRef50_Q0AX27 Cluster: PolyA polymerase family protein precurs... 36 3.4 UniRef50_Q01QB6 Cluster: FMN-dependent alpha-hydroxy acid dehydr... 36 3.4 UniRef50_A7AGI1 Cluster: Putative uncharacterized protein; n=1; ... 36 3.4 UniRef50_A6SYD0 Cluster: Signal transduction protein; n=1; Janth... 36 3.4 UniRef50_A5VE54 Cluster: L-lactate dehydrogenase; n=1; Sphingomo... 36 3.4 UniRef50_Q2V3V9 Cluster: Uncharacterized protein At3g14420.3; n=... 36 3.4 UniRef50_Q86H81 Cluster: Similar to Oceanobacillus iheyensis. 2-... 36 3.4 UniRef50_Q4FYS1 Cluster: Cysteine peptidase, Clan CA, family C2,... 36 3.4 UniRef50_Q2GMR8 Cluster: Putative uncharacterized protein; n=1; ... 36 3.4 UniRef50_Q0CRW0 Cluster: Putative uncharacterized protein; n=1; ... 36 3.4 UniRef50_P95951 Cluster: Orf c04012 protein; n=4; Sulfolobaceae|... 36 3.4 UniRef50_A3CTZ5 Cluster: PAS/PAC sensor signal transduction hist... 36 3.4 UniRef50_A2BLX4 Cluster: Conserved archaeal protein; n=1; Hypert... 36 3.4 UniRef50_P35500 Cluster: Sodium channel protein para; n=55; Arth... 36 3.4 UniRef50_Q8DGQ5 Cluster: Putative N-acetylmannosamine-6-phosphat... 36 3.4 UniRef50_Q9LRS0 Cluster: Probable peroxisomal (S)-2-hydroxy-acid... 36 3.4 UniRef50_UPI0000E4606B Cluster: PREDICTED: similar to MGC108441 ... 35 4.5 UniRef50_UPI00006D0109 Cluster: hypothetical protein TTHERM_0082... 35 4.5 UniRef50_Q8F0T1 Cluster: Putative uncharacterized protein; n=4; ... 35 4.5 UniRef50_Q89LA1 Cluster: Blr4646 protein; n=3; Bradyrhizobiaceae... 35 4.5 UniRef50_Q55552 Cluster: IMP dehydrogenase; n=8; Cyanobacteria|R... 35 4.5 UniRef50_Q1NPF0 Cluster: CBS; n=1; delta proteobacterium MLMS-1|... 35 4.5 UniRef50_Q1LA70 Cluster: 2-nitropropane dioxygenase, NPD; n=1; R... 35 4.5 UniRef50_Q0F1M3 Cluster: Acetoin utilization protein AcuB; n=1; ... 35 4.5 UniRef50_A7HKN4 Cluster: 2-nitropropane dioxygenase NPD; n=1; Fe... 35 4.5 UniRef50_A4ASV9 Cluster: Cyclic nucleotide-binding domain (CNMP-... 35 4.5 UniRef50_A3WHK4 Cluster: Putative signal-transduction protein wi... 35 4.5 UniRef50_A1W3D8 Cluster: (S)-2-hydroxy-acid oxidase; n=2; Proteo... 35 4.5 UniRef50_A1U351 Cluster: FMN-dependent alpha-hydroxy acid dehydr... 35 4.5 UniRef50_A0JYV5 Cluster: 2-nitropropane dioxygenase, NPD; n=2; A... 35 4.5 UniRef50_A5BR80 Cluster: Putative uncharacterized protein; n=1; ... 35 4.5 UniRef50_Q2HCD3 Cluster: Putative uncharacterized protein; n=1; ... 35 4.5 UniRef50_Q9HKI7 Cluster: Inosine-5'-monophosphate dehydrogenase ... 35 4.5 UniRef50_Q4JBJ8 Cluster: CBS domain protein; n=4; Sulfolobaceae|... 35 4.5 UniRef50_Q8G4D5 Cluster: Possible prolidase (X-Pro dipeptidase) ... 35 5.9 UniRef50_Q81UX7 Cluster: Regulatory protein TenI; n=10; Bacillus... 35 5.9 UniRef50_Q7NHC3 Cluster: Glr2614 protein; n=1; Gloeobacter viola... 35 5.9 UniRef50_Q4A6K5 Cluster: Putative N-acetylmannosamine-6-p epimer... 35 5.9 UniRef50_Q21XZ1 Cluster: CBS domain containing membrane protein;... 35 5.9 UniRef50_Q1NKC6 Cluster: CBS:Phosphoesterase, RecJ-like:Polynucl... 35 5.9 UniRef50_Q1F0W8 Cluster: Dihydroorotate dehydrogenase 1; n=1; Cl... 35 5.9 UniRef50_Q1CWF0 Cluster: Alanine racemase; n=2; Cystobacterineae... 35 5.9 UniRef50_Q0SII9 Cluster: Probable 2-nitropropane dioxygenase; n=... 35 5.9 UniRef50_Q0G2G5 Cluster: CBS domain containing membrane protein;... 35 5.9 UniRef50_Q0FCN2 Cluster: Inosine-5'-monophosphate dehydrogenase;... 35 5.9 UniRef50_A7BWJ0 Cluster: Cl-channel, voltage gated; n=1; Beggiat... 35 5.9 UniRef50_A6WDG0 Cluster: CBS domain containing protein precursor... 35 5.9 UniRef50_A6UKQ5 Cluster: L-lactate dehydrogenase; n=2; Alphaprot... 35 5.9 UniRef50_A6G8F7 Cluster: CBS domain protein; n=1; Plesiocystis p... 35 5.9 UniRef50_A6E6Z2 Cluster: Phosphoribosylformimino-5-aminoimidazol... 35 5.9 UniRef50_A3VMI7 Cluster: L-lactate dehydrogenase; n=3; Rhodobact... 35 5.9 UniRef50_A3DD07 Cluster: Thiamine-phosphate pyrophosphorylase; n... 35 5.9 UniRef50_A0FY21 Cluster: Putative signal transduction protein wi... 35 5.9 UniRef50_Q8MPT5 Cluster: Putative uncharacterized protein T01B6.... 35 5.9 UniRef50_A2QFW7 Cluster: Putative uncharacterized protein; n=1; ... 35 5.9 UniRef50_A2QBL3 Cluster: Remark: 4 possible sequencing errors we... 35 5.9 UniRef50_Q8TVZ3 Cluster: CBS-domain; n=1; Methanopyrus kandleri|... 35 5.9 UniRef50_Q6L002 Cluster: CBS domain containing protein; n=4; The... 35 5.9 UniRef50_O27293 Cluster: Inosine-5'-monophosphate dehydrogenase ... 35 5.9 UniRef50_Q12WB7 Cluster: CBS domain protein; n=4; Methanosarcina... 35 5.9 UniRef50_A0RYM1 Cluster: Phosphate-binding enzymes, TIM-barrel f... 35 5.9 UniRef50_A0RYL5 Cluster: CBS domain; n=1; Cenarchaeum symbiosum|... 35 5.9 UniRef50_Q57564 Cluster: Uncharacterized protein MJ0100; n=24; c... 35 5.9 UniRef50_Q894H0 Cluster: 1-deoxy-D-xylulose-5-phosphate synthase... 35 5.9 UniRef50_UPI0000DAECD7 Cluster: hypothetical protein CburR_01002... 34 7.8 UniRef50_UPI00004987F4 Cluster: isopentenyl-diphosphate delta-is... 34 7.8 UniRef50_Q97L84 Cluster: CBS domains; n=5; Clostridium|Rep: CBS ... 34 7.8 UniRef50_Q81YV1 Cluster: Glutamate synthase, large subunit, puta... 34 7.8 UniRef50_Q7NT73 Cluster: Probable TonB-dependent receptor; n=1; ... 34 7.8 UniRef50_Q72GV4 Cluster: Lactate 2-monooxygenase; n=1; Thermus t... 34 7.8 UniRef50_Q64WA1 Cluster: Dioxygenase; n=24; cellular organisms|R... 34 7.8 UniRef50_Q47UD0 Cluster: CBS domain protein; n=2; Alteromonadale... 34 7.8 UniRef50_Q7WYR2 Cluster: Imidazole glycerol phosphate synthase, ... 34 7.8 UniRef50_Q3WCL7 Cluster: L-lactate dehydrogenase; n=1; Frankia s... 34 7.8 UniRef50_Q3ESZ4 Cluster: Enoyl-[acyl-carrier protein] reductase;... 34 7.8 UniRef50_Q2B3A9 Cluster: Acetoin utilization protein; n=2; Bacil... 34 7.8 UniRef50_Q1AX99 Cluster: CBS domain containing membrane protein;... 34 7.8 UniRef50_Q027N8 Cluster: FMN-dependent alpha-hydroxy acid dehydr... 34 7.8 UniRef50_A6LTL9 Cluster: CBS domain containing protein; n=1; Clo... 34 7.8 UniRef50_A4VT21 Cluster: L-lactate dehydrogenase (FMN-dependent)... 34 7.8 UniRef50_A4CMN3 Cluster: Putative uncharacterized protein; n=1; ... 34 7.8 UniRef50_A4BBH2 Cluster: CBS-domain-containing protein; n=1; Rei... 34 7.8 UniRef50_A1SFC7 Cluster: CBS domain containing protein; n=1; Noc... 34 7.8 UniRef50_A0LZM5 Cluster: Protein containing response regulator r... 34 7.8 UniRef50_A1D3U7 Cluster: CBS and PB1 domain protein; n=17; Ascom... 34 7.8 UniRef50_Q3IR34 Cluster: CBS domain protein 5; n=2; Halobacteria... 34 7.8 UniRef50_O26740 Cluster: Conserved protein; n=1; Methanothermoba... 34 7.8 UniRef50_Q5Y0L9 Cluster: Inosine-5'-monophosphate dehydrogenase;... 34 7.8 UniRef50_Q5Y0L8 Cluster: Inosine-5'-monophosphate dehydrogenase;... 34 7.8 UniRef50_A0B5X3 Cluster: Putative signal transduction protein wi... 34 7.8 UniRef50_P32987 Cluster: Uncharacterized 17.7 kDa protein in bps... 34 7.8 UniRef50_O67328 Cluster: 1-(5-phosphoribosyl)-5-[(5-phosphoribos... 34 7.8 UniRef50_P05414 Cluster: Peroxisomal (S)-2-hydroxy-acid oxidase;... 34 7.8 >UniRef50_P20839 Cluster: Inosine-5'-monophosphate dehydrogenase 1; n=135; cellular organisms|Rep: Inosine-5'-monophosphate dehydrogenase 1 - Homo sapiens (Human) Length = 514 Score = 739 bits (1826), Expect = 0.0 Identities = 355/503 (70%), Positives = 419/503 (83%), Gaps = 5/503 (0%) Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70 DGL+A+ FA+++GLTYNDFL+LPG+IDF A+EVDLTS LT+KI LK PL+S+PMDTVTE Sbjct: 16 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 75 Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130 ADMAI+MAL GGIG IHHNCTPE+QANEV KVKK++ GFI DPV + P +TV DVLEAK Sbjct: 76 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 135 Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSL-KEVMTPINDMITAQLGVTLQ 189 ++GF+G PIT+ G +G +L+GIVTSRDIDF H +L EVMTP +++ A GVTL+ Sbjct: 136 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 195 Query: 190 DANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDT 249 +AN IL++SKKGKLPI+N+ ELVA+IARTDLKK R YP ASKDS KQLL GAA+GTR+ Sbjct: 196 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 255 Query: 250 DRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309 D+ RL LL GVDVIVLDSSQGNS YQI M+ YIK+ YP +QV+GGNVVT QAKNLID Sbjct: 256 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 315 Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369 AGVD LRVGMG GSICITQEVMACG PQ TAVY+VA YAR F VP+IADGGIQ+VGH++K Sbjct: 316 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 375 Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH 429 +LALGASTVMMGSLLA T+EAPGEYFFSDGVRLKKYRGMGSL+AME S+ RYF Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEK---SSSSQKRYF- 431 Query: 430 KESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFM 489 E DK ++AQGVSGSI DKGS+ +F+PYL AG+QH CQD+GARS+SVLR M +SG+L+F Sbjct: 432 SEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFE 491 Query: 490 KRTYSAQLEGNVHGLFSYEKRLF 512 KRT SAQ+EG VHGL SYEKRL+ Sbjct: 492 KRTMSAQIEGGVHGLHSYEKRLY 514 >UniRef50_P12268 Cluster: Inosine-5'-monophosphate dehydrogenase 2; n=30; Euteleostomi|Rep: Inosine-5'-monophosphate dehydrogenase 2 - Homo sapiens (Human) Length = 514 Score = 725 bits (1792), Expect = 0.0 Identities = 350/503 (69%), Positives = 418/503 (83%), Gaps = 5/503 (0%) Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70 DGL+A+ F +GLTYNDFL+LPGYIDFTA++VDLTS LTKKI LK PLVS+PMDTVTE Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75 Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130 A MAI+MAL GGIG IHHNCTPE+QANEV KVKKY+ GFI DPV + P++ V DV EAK Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135 Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPH-LSLKEVMTPINDMITAQLGVTLQ 189 ++GF G PIT G++G RL+GI++SRDIDF + + H L+E+MT D++ A G+TL+ Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLK 195 Query: 190 DANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDT 249 +AN IL++SKKGKLPI+N D ELVA+IARTDLKK R YP ASKD+ KQLL GAAIGT + Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255 Query: 250 DRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309 D+ RL LL GVDV+VLDSSQGNS +QI MIKYIK+ YP +QV+GGNVVT QAKNLID Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315 Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369 AGVDALRVGMGSGSICITQEV+ACG PQATAVY+V+ YAR F VPVIADGGIQ+VGHI K Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375 Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH 429 +LALGASTVMMGSLLA T+EAPGEYFFSDG+RLKKYRGMGSL+AM D S+ +RYF Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM---DKHLSSQNRYF- 431 Query: 430 KESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFM 489 E+DK +VAQGVSG++ DKGS+ +F+PYL AG+QHSCQD+GA+S++ +R M +SG+L+F Sbjct: 432 SEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFE 491 Query: 490 KRTYSAQLEGNVHGLFSYEKRLF 512 KRT SAQ+EG VH L SYEKRLF Sbjct: 492 KRTSSAQVEGGVHSLHSYEKRLF 514 >UniRef50_P21620 Cluster: Inosine-5'-monophosphate dehydrogenase; n=11; Eukaryota|Rep: Inosine-5'-monophosphate dehydrogenase - Leishmania donovani Length = 514 Score = 516 bits (1272), Expect = e-145 Identities = 250/504 (49%), Positives = 352/504 (69%), Gaps = 6/504 (1%) Query: 9 LRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTV 68 ++DG +AE+ F +GLTYNDF++LPG+IDF A +V+++ TK+I L P+VS+PMDT+ Sbjct: 13 IKDGCTAEELF-RGDGLTYNDFIILPGFIDFGAADVNISGQFTKRIRLHIPIVSSPMDTI 71 Query: 69 TEADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEA 128 TE +MA +MAL GG+G++H+NCT E Q V VK Y++GFI P + P +++++ Sbjct: 72 TENEMAKTMALMGGVGVLHNNCTVERQVEMVKSVKAYRNGFISKPKSVPPNTPISNIIRI 131 Query: 129 KKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTL 188 K++ G +G +T+NG G+L+GIV ++DID+ + + + VMT M + + L Sbjct: 132 KEEKGISGILVTENGDPHGKLLGIVCTKDIDYVK-NKDTPVSAVMTRREKMTVERAPIQL 190 Query: 189 QDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRD 248 ++A +L +S+ G LPI+N + E+V L +R D +AR YP+++ D + +L+ AA TR Sbjct: 191 EEAMDVLNRSRYGYLPIVNENDEVVNLCSRRDAVRARDYPHSTLDKSGRLICAAATSTRP 250 Query: 249 TDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLI 308 D+ R+ L + GVDV+VLDSSQGN+ YQI IK++K TYP ++VV GNVVT+ QAKNLI Sbjct: 251 EDKRRVAALADVGVDVLVLDSSQGNTIYQIAFIKWVKSTYPHLEVVAGNVVTQDQAKNLI 310 Query: 309 DAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHII 368 DAG D +R+GMGSGSICITQEV+ACG PQ TAVY+VA Y VP ADGG++ VG I Sbjct: 311 DAGADGIRIGMGSGSICITQEVLACGRPQGTAVYKVAQYCASRGVPCTADGGLRQVGDIC 370 Query: 369 KSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYF 428 K+LA+GA+ M+G +L+GT+E PGEYFF GVRLK YRGMGSLEAM GK S RY Sbjct: 371 KALAIGANCAMLGGMLSGTTETPGEYFFKGGVRLKVYRGMGSLEAM--SQGKESG-KRYL 427 Query: 429 HKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRF 488 E++ +VAQGVSG++VDKGS + + Y+ G+Q S QD+G S +RE ++G + F Sbjct: 428 -SENEAVQVAQGVSGNVVDKGSAAKLIAYVSKGLQQSAQDIGEISFDAIREKMYAGQVLF 486 Query: 489 MKRTYSAQLEGNVHGLFSYEKRLF 512 +R+ +AQ EG VH L SYEK+LF Sbjct: 487 SRRSPTAQGEGGVHSLHSYEKKLF 510 >UniRef50_O96387 Cluster: Inosine-5'-monophosphate dehydrogenase; n=3; Plasmodium|Rep: Inosine-5'-monophosphate dehydrogenase - Plasmodium falciparum Length = 510 Score = 490 bits (1208), Expect = e-137 Identities = 242/511 (47%), Positives = 339/511 (66%), Gaps = 10/511 (1%) Query: 9 LRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTV 68 + G A++ F TY+ + +PGYIDF ++DLT+ +T I LK P++S+PMDTV Sbjct: 1 MASGWKADEVFGGVMSYTYDVIICMPGYIDFALSDIDLTNNMTDNITLKTPVISSPMDTV 60 Query: 69 TEADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEA 128 T M+I++AL GG+G+IH+N + E Q EV KVK++++GFI DP PE+TVADVLE Sbjct: 61 TGHKMSIALALSGGLGVIHNNMSIEKQIEEVKKVKRFENGFIFDPYTFSPEHTVADVLET 120 Query: 129 KKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTL 188 K + G+ YPIT +GK+G +L+GI+T D + + + + ++MT D++T + L Sbjct: 121 KNRVGYKSYPITVDGKVGSKLVGIITGIDYLYLT-NKSMKIGDIMT--TDVVTGSYPINL 177 Query: 189 QDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRD 248 DAN +L KK LPI+N + EL+AL+ R D+ K R +P+ASK NKQL+VGA+I TR+ Sbjct: 178 SDANKVLCDEKKSVLPIVNKNNELIALVCRNDMHKNRIFPHASKSQNKQLIVGASISTRE 237 Query: 249 TDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLI 308 D ER L+ N +DVI +DSSQGNS YQI IK IK +P+I ++GGNVVT QAKNLI Sbjct: 238 HDLERANQLIKNMIDVICIDSSQGNSIYQIDTIKKIKSAHPDIPIIGGNVVTSQQAKNLI 297 Query: 309 DAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHII 368 DAG D LR+GMGSGSIC TQ+V A G Q TAVY V+ YA N+ IADGGI++ G+I+ Sbjct: 298 DAGADVLRIGMGSGSICTTQDVCAVGRAQGTAVYHVSKYAHTRNIKTIADGGIKNSGNIV 357 Query: 369 KSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSA----- 423 K+L+LGA VM+G+LLA T E+ EY+F + VRLK YRGMGS+EAM +K + Sbjct: 358 KALSLGADFVMLGNLLAATEESCSEYYFENNVRLKIYRGMGSMEAMYNKGFNSKSRYLVD 417 Query: 424 --MSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMS 481 + Y + D+ +V+QGVS S+VDKGSVL +P+L ++H Q +G R++ L Sbjct: 418 ERKNEYTDENIDEIKVSQGVSASLVDKGSVLNLIPHLFKAVKHGFQSMGIRNIPELHSKL 477 Query: 482 HSGDLRFMKRTYSAQLEGNVHGLFSYEKRLF 512 +SGD+RF R+++ EG V + + F Sbjct: 478 YSGDIRFDVRSFNTIKEGKVSDNLIFNNKKF 508 >UniRef50_Q01F10 Cluster: IpdH inosine 5'-phosphate dehydrogenase; n=2; Ostreococcus|Rep: IpdH inosine 5'-phosphate dehydrogenase - Ostreococcus tauri Length = 502 Score = 481 bits (1187), Expect = e-134 Identities = 243/502 (48%), Positives = 342/502 (68%), Gaps = 10/502 (1%) Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70 DG SAE F TY+D + PG+IDF A++VDL++ +++ I ++ PLVS+PMDTVTE Sbjct: 5 DGYSAEVLFNQGFCYTYDDVIFHPGFIDFAADQVDLSTRVSRNITIRTPLVSSPMDTVTE 64 Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130 ++MA++MA GG+G +H+N T E Q V +VK + G++ +P MGP T++++ + Sbjct: 65 SEMAVAMAEVGGMGFLHYNMTMESQVEHVKRVKSHNPGYVANPAIMGPSATLSELDKLLT 124 Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQD 190 GFT +T++G G L+G+VT+RDI+F D +L EVMT + ++ +TLQ+ Sbjct: 125 ARGFTSVCVTEDGASEGTLLGLVTTRDIEFVR-DRTTALSEVMTTVGKLVLGSTDMTLQE 183 Query: 191 ANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASK---DSNKQLLVGAAIGTR 247 L + K+GKLPI+N G L L+ R ++K + P A D++ +LL GAAIGTR Sbjct: 184 NETTLLECKRGKLPIVNRHGCLTGLLTRANVKARLNRPAAGAPALDNHGKLLCGAAIGTR 243 Query: 248 DTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNL 307 DTDR R + L GV+ I+LDSSQG+S YQ++MIK++K P++ V+ GNVVT+ QA+ L Sbjct: 244 DTDRVRAQQLFGAGVNAIILDSSQGDSVYQLEMIKFLKNELPQLDVIAGNVVTQQQARRL 303 Query: 308 IDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHI 367 ++AG D LRVGMGSGSIC TQEV A G QATAVY+V AR F+VP+IADGGIQ+ GHI Sbjct: 304 LEAGADGLRVGMGSGSICTTQEVCAVGRGQATAVYKVGQVAREFDVPIIADGGIQNSGHI 363 Query: 368 IKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRY 427 +K+LALGA+ M GS+ +G++EAPG+YF+ DG R+KKYRGMGSL+AM+ KGS SRY Sbjct: 364 VKALALGANVAMCGSVFSGSTEAPGQYFYQDGARVKKYRGMGSLDAMK----KGSD-SRY 418 Query: 428 FHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLR 487 ES ++AQGVSG++ DKGS+ +PYL G + QDLGA S+ + +M +G + Sbjct: 419 L-SESGHLKIAQGVSGTVRDKGSIKSTIPYLIHGAKQGFQDLGADSLEKVHQMLANGLMT 477 Query: 488 FMKRTYSAQLEGNVHGLFSYEK 509 RT +AQ EG +H + SY K Sbjct: 478 MEVRTNAAQKEGGIHDMHSYTK 499 >UniRef50_Q4VRV8 Cluster: Inosine 5'monophosphate dehydrogenase; n=2; Toxoplasma gondii|Rep: Inosine 5'monophosphate dehydrogenase - Toxoplasma gondii Length = 551 Score = 481 bits (1186), Expect = e-134 Identities = 238/410 (58%), Positives = 306/410 (74%), Gaps = 5/410 (1%) Query: 9 LRDGLSAEDTFANSE-GLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDT 67 + DG AE F + G TY+D +L+PG+IDF +VDL++ +T+ + ++ P+VS+PMDT Sbjct: 1 MADGWDAEKIFNTTVFGFTYDDLILMPGHIDFGVNDVDLSTRITRNLHVRTPIVSSPMDT 60 Query: 68 VTEADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLE 127 VTE MAI AL GG+G+IH+N Q EV KVK+Y++GFI DP + P ++VADV Sbjct: 61 VTEHRMAIGCALMGGMGVIHNNMETARQVAEVQKVKRYENGFILDPFVLRPSDSVADVYR 120 Query: 128 AKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVT 187 K+K G++ PIT G LGG+L+GIVTSRDIDF D H L EVMT +D++ V Sbjct: 121 IKEKYGYSSVPITDTGMLGGKLLGIVTSRDIDFLT-DVHTPLSEVMT--SDLVVGHEPVQ 177 Query: 188 LQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTR 247 L +AN +L +SKKGKLPI+N++ ELVALI+R DLKK R +P ASKDSNKQLLVGAA+ T+ Sbjct: 178 LAEANELLRESKKGKLPIVNDNFELVALISRNDLKKNREFPLASKDSNKQLLVGAAVSTK 237 Query: 248 DTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNL 307 D ER K L G DV+V+DSSQG+S YQ+ ++K +K +PE+Q++GGNVVT QAK+L Sbjct: 238 PHDIERAKALQEAGADVLVVDSSQGDSIYQVDLVKRLKAAFPELQIIGGNVVTARQAKSL 297 Query: 308 IDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYAR-HFNVPVIADGGIQSVGH 366 IDAGVD LR+GMGSGSIC TQ V A G QATAVY V YAR H +VP IADGGIQ+ GH Sbjct: 298 IDAGVDGLRIGMGSGSICTTQVVCAVGRAQATAVYHVCKYAREHGDVPCIADGGIQNSGH 357 Query: 367 IIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMES 416 ++K+LALGA+ VMMGS+LAGT EAPGEY+F +GVR+K YRGMGSL+AM + Sbjct: 358 VMKALALGANAVMMGSMLAGTEEAPGEYYFHNGVRVKTYRGMGSLDAMRA 407 Score = 91.9 bits (218), Expect = 4e-17 Identities = 47/101 (46%), Positives = 69/101 (68%), Gaps = 2/101 (1%) Query: 412 EAMESKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGA 471 EA + GSA +RYF E+ RVAQGVSG +VDKG+V++ +PY+ G++H QD+GA Sbjct: 452 EASRTSTSTGSA-ARYF-AENQTIRVAQGVSGCVVDKGTVMQLIPYVIQGVKHGMQDIGA 509 Query: 472 RSVSVLREMSHSGDLRFMKRTYSAQLEGNVHGLFSYEKRLF 512 R++ L G+LRF R+ +AQ EG+VH L S+E++L+ Sbjct: 510 RTLRDLHAQLVGGELRFDVRSGAAQREGDVHDLHSFERKLY 550 >UniRef50_Q4UCL4 Cluster: Inosine-5'-monophosphate dehydrogenase, putative; n=7; Aconoidasida|Rep: Inosine-5'-monophosphate dehydrogenase, putative - Theileria annulata Length = 511 Score = 472 bits (1163), Expect = e-131 Identities = 244/507 (48%), Positives = 353/507 (69%), Gaps = 18/507 (3%) Query: 9 LRDGLSAEDTFANSE-GLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDT 67 + DG SA + F ++ L+Y D ++LPGYI + ++VDL+S +T+ I L+ P++S+PMDT Sbjct: 1 MADGYSAAEFFNFTKLSLSYEDLIILPGYIRDSVDKVDLSSNVTRNIKLRIPILSSPMDT 60 Query: 68 VTEADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLE 127 VTE+ MA +MAL GG+G+IH+N + + EV VK++++GF+ +PVC+ P +TV+D +E Sbjct: 61 VTESKMATAMALLGGLGVIHNNLSIDNLIKEVKAVKRFENGFVHNPVCLKPTSTVSDWVE 120 Query: 128 AKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVT 187 + K GFT PIT +G G +L+GIVT D+ F E ++SL+E+M+ +++ + + Sbjct: 121 IRDKLGFTSVPITSDGNPGSKLLGIVTKTDMYFVE-SKNVSLEEIMS--TNLVVGKHPMK 177 Query: 188 LQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTR 247 L DAN +L SKKG LPI+N D EL++++ R+D K++ YP ASKD NKQLLVGAAI T Sbjct: 178 LNDANELLFMSKKGVLPIVNEDYELMSIVTRSDFYKSKLYPYASKDDNKQLLVGAAISTN 237 Query: 248 D----TDR----ERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVV 299 + DR E K L++ VDVI++DSSQGNS +QI +IK +K YP +Q++GGNVV Sbjct: 238 NFANGFDRVNGLEVAKKLIDAKVDVILVDSSQGNSVFQIDLIKQLKSAYPNVQIIGGNVV 297 Query: 300 TRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYA-RHFN-VPVIA 357 + QAKN+++AG D+++VGMG GSIC TQ + G QAT+VY V+ Y H+N VPVIA Sbjct: 298 SAQQAKNVLEAGCDSIKVGMGIGSICTTQNICGVGRGQATSVYYVSRYTFEHWNGVPVIA 357 Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAME-- 415 DGGI++ G I+K+L+LGAS VM GS+ AG+ EAPGEY+F++GVR+K YRGMGS +A+ Sbjct: 358 DGGIKTSGDIVKALSLGASCVMGGSIFAGSKEAPGEYYFNNGVRMKSYRGMGSKDAINDS 417 Query: 416 -SKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSV 474 G ++SRY H D+ ++QGVSG ++DKGSV LP L G++H Q++GA SV Sbjct: 418 LQNTGLMGSLSRY-HLVDDQKIISQGVSGLVIDKGSVNNILPNLTQGVKHGLQNIGAFSV 476 Query: 475 SVLREMSHSGDLRFMKRTYSAQLEGNV 501 L E +SG LR +RT + ++ NV Sbjct: 477 KELHEALYSGQLRLEQRTAQSIVDANV 503 >UniRef50_P47996 Cluster: Inosine-5'-monophosphate dehydrogenase; n=9; core eudicotyledons|Rep: Inosine-5'-monophosphate dehydrogenase - Arabidopsis thaliana (Mouse-ear cress) Length = 503 Score = 434 bits (1069), Expect = e-120 Identities = 235/512 (45%), Positives = 332/512 (64%), Gaps = 20/512 (3%) Query: 9 LRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTV 68 L DG A+ FA TY+D + LP +IDF+ + V L++ L++++ L P VS+PMDTV Sbjct: 4 LEDGFPADKLFAQGYSYTYDDVIFLPHFIDFSTDAVSLSTRLSRRVPLSIPCVSSPMDTV 63 Query: 69 TEADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEA 128 +E+ MA +MA GGIGI+H+NC QA+ + + K KH D PE + L+A Sbjct: 64 SESHMAAAMASLGGIGIVHYNCGIAAQASIIRQAKSLKHPIASDAGVKFPEYEITS-LDA 122 Query: 129 KKKNGFTGYPITQNGKLGG-RLIGIVTS---RDIDFREGDPHLSLKEVMTPINDM-ITAQ 183 + F + Q G + +L+G VT + +++ + + + + + M + Sbjct: 123 FGPSSFVF--VEQTGTMTTPKLLGYVTKSQWKRMNYEQRE--MKIYDYMKSCDSSDYCVP 178 Query: 184 LGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDS---NKQLLV 240 + + ++LE +KG + ++ DGE V ++ + D+++ + YP + + + + +V Sbjct: 179 WEIDFEKLEFVLEDKQKGFV-VLERDGETVNVVTKDDIQRVKGYPKSGPGTVGPDGEWMV 237 Query: 241 GAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVT 300 GAAIGTR++D+ERL+ LVN GV+ +VLDSSQGNS YQ++MIKY+K+TYPE+ V+GGNVVT Sbjct: 238 GAAIGTRESDKERLEHLVNVGVNAVVLDSSQGNSIYQLEMIKYVKKTYPELDVIGGNVVT 297 Query: 301 RMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGG 360 QA+NLI AGVD LRVGMGSGSIC TQEV A G QATAVY+V S A +PVIADGG Sbjct: 298 MYQAQNLIQAGVDGLRVGMGSGSICTTQEVCAVGRGQATAVYKVCSIAAQSGIPVIADGG 357 Query: 361 IQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGK 420 I + GHI+K+L LGASTVMMGS LAG++EAPG Y +++G R+KKYRGMGSLEAM K Sbjct: 358 ISNSGHIVKALVLGASTVMMGSFLAGSTEAPGGYEYTNGKRIKKYRGMGSLEAMT----K 413 Query: 421 GSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREM 480 GS RY ++ K ++AQGV G++ DKGSVL+ +PY ++ QDLGA S+ + Sbjct: 414 GSD-QRYLGDQT-KLKIAQGVVGAVADKGSVLKLIPYTMHAVKQGFQDLGASSLQSAHGL 471 Query: 481 SHSGDLRFMKRTYSAQLEGNVHGLFSYEKRLF 512 S LR RT +AQ+EG VHGL SYEK+ F Sbjct: 472 LRSNILRLEARTGAAQVEGGVHGLVSYEKKSF 503 >UniRef50_A7QMJ8 Cluster: Chromosome chr19 scaffold_126, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr19 scaffold_126, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 578 Score = 427 bits (1053), Expect = e-118 Identities = 240/508 (47%), Positives = 327/508 (64%), Gaps = 19/508 (3%) Query: 9 LRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTV 68 + DG A F TY+D + PGYIDF A+ V L + L++ + L P V++PMDTV Sbjct: 86 IEDGFPAVKLFNQGYSYTYDDVIFHPGYIDFPADAVQLGTKLSRNVHLSIPCVASPMDTV 145 Query: 69 TEADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEA 128 TE+ MA++MA GG+GIIH N + QA V K + F+ DPV ++V V + Sbjct: 146 TESAMAVAMATVGGVGIIHSNNSAAEQAALVRSAKSRRVPFVSDPVVKSAFDSVDSVSDF 205 Query: 129 KKKNGFTGYP-ITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVT 187 G Y +T++G +++G+V D + + D + + E M + + A Sbjct: 206 ----GSAPYVLVTESGTAKSKMLGVVLRSDWE-KLSDKGVKVCEYMVSSPESVPASYDFE 260 Query: 188 LQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNA---SKDSNKQLLVGAAI 244 Q A Y+ K K +P++ +D E+V ++ D+++ R +P S D+ + LVGAAI Sbjct: 261 -QVAGYLAAK-KLSFVPLVRDD-EVVDVVTTADVERIRGFPKLGMPSLDAKGEFLVGAAI 317 Query: 245 GTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQA 304 GTR++D+ERL+ LV G +VIVLDSSQGNS YQI+M KY K+ +PE+ V+GGNVVT QA Sbjct: 318 GTRESDKERLEHLVKAGANVIVLDSSQGNSIYQIEMTKYAKKMFPEVDVIGGNVVTIRQA 377 Query: 305 KNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSV 364 +NLI AGVD LRVGMGSGSIC TQEV A G QATAVY+V+S A VPVIADGGI + Sbjct: 378 QNLIQAGVDGLRVGMGSGSICTTQEVCAVGRGQATAVYKVSSIAERSGVPVIADGGISNS 437 Query: 365 GHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAM 424 GHI+K+L LGASTVMMGS LAG+SEAPG Y +G+++KKYRGMGSLEAM KGS Sbjct: 438 GHIVKALTLGASTVMMGSFLAGSSEAPGAYENKNGLKIKKYRGMGSLEAMT----KGSD- 492 Query: 425 SRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSG 484 +RY ++ K ++AQGV G++ DKGSVL+F+PY ++ QDLGA S+ ++ S Sbjct: 493 ARYL-GDTAKLKIAQGVVGAVADKGSVLKFIPYTMQAVKQGFQDLGASSLQSAHDLLRS- 550 Query: 485 DLRFMKRTYSAQLEGNVHGLFSYEKRLF 512 +LR RT +AQ+EG VHGL S+EK+ F Sbjct: 551 ELRLEVRTGAAQVEGGVHGLVSHEKKYF 578 >UniRef50_Q4SBU2 Cluster: Chromosome 19 SCAF14664, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 19 SCAF14664, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 571 Score = 419 bits (1031), Expect = e-115 Identities = 213/322 (66%), Positives = 250/322 (77%), Gaps = 3/322 (0%) Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEV-DLTSPLT-KKILLKAPLVSTPMDTV 68 DGLSA+ F+ +GLTY TAEE+ LT KKI LK PL+S+PMDTV Sbjct: 17 DGLSAQQLFSIGDGLTYKSDQQCVVSDGHTAEELCSKGDGLTYKKITLKTPLISSPMDTV 76 Query: 69 TEADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEA 128 TE+ MAI+MAL GGIGIIHHNCTPE+QANEV KVK+++ GFI DPV M P +TV DV+EA Sbjct: 77 TESAMAIAMALMGGIGIIHHNCTPEFQANEVRKVKRFEQGFITDPVVMSPRHTVGDVVEA 136 Query: 129 KKKNGFTGYPITQNGKLGGRLIGIVTSRDIDF-REGDPHLSLKEVMTPINDMITAQLGVT 187 K ++GF+G PIT+ GK+G +L+GIVTSRDIDF E D L+E MT D++ A GVT Sbjct: 137 KTRHGFSGIPITETGKMGSKLVGIVTSRDIDFLSEKDHDKPLEEAMTKREDLVVAPAGVT 196 Query: 188 LQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTR 247 L++AN IL++SKKGKLPI+NN+ ELVA+IARTDLKK R YP ASKDS KQLL GAAIGTR Sbjct: 197 LKEANDILQRSKKGKLPIVNNNDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGTR 256 Query: 248 DTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNL 307 D D+ RL LLV GVDV+VLDSSQGNS +QI MI YIK+ Y ++QVVGGNVVT QAKNL Sbjct: 257 DDDKYRLDLLVQAGVDVVVLDSSQGNSVFQISMINYIKQKYADLQVVGGNVVTAAQAKNL 316 Query: 308 IDAGVDALRVGMGSGSICITQE 329 IDAGVDALRVGMG GSICITQE Sbjct: 317 IDAGVDALRVGMGCGSICITQE 338 Score = 260 bits (637), Expect = 6e-68 Identities = 124/177 (70%), Positives = 150/177 (84%), Gaps = 4/177 (2%) Query: 330 VMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSE 389 VMACG PQ T+VY+VA YAR F+VPVIADGGIQ+VGH++K+L+LGASTVMMGSLLA T+E Sbjct: 399 VMACGRPQGTSVYKVAEYARRFSVPVIADGGIQTVGHVVKALSLGASTVMMGSLLAATTE 458 Query: 390 APGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKG 449 APGEYFF+DGVRLKKYRGMGSL+AME S+ RYF E DK +VAQGVSGS+ DKG Sbjct: 459 APGEYFFADGVRLKKYRGMGSLDAMEKST---SSQKRYF-SEGDKVKVAQGVSGSVQDKG 514 Query: 450 SVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNVHGLFS 506 S+ +F+PYL AG+QH CQD+GA+S+S+LR M +SG+L+F KRT SAQ+EG VHGL S Sbjct: 515 SIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKFEKRTMSAQVEGGVHGLHS 571 >UniRef50_A6R4D7 Cluster: Inosine-5'-monophosphate dehydrogenase; n=1; Ajellomyces capsulatus NAm1|Rep: Inosine-5'-monophosphate dehydrogenase - Ajellomyces capsulatus NAm1 Length = 508 Score = 383 bits (943), Expect = e-105 Identities = 231/515 (44%), Positives = 316/515 (61%), Gaps = 59/515 (11%) Query: 11 DGLSAEDTFANSE--GLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTV 68 DGL + + LTYNDFL+LPGYI F A +V L +P+T++I LKAPL+S+PMDTV Sbjct: 39 DGLDINQLIDSEKRGALTYNDFLILPGYIGFPASDVSLETPVTRRITLKAPLLSSPMDTV 98 Query: 69 TEADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEA 128 TE MAI MAL GG+G+IHHNC+ E QAN V KVK+Y++GFI +PV + P TVA+ Sbjct: 99 TEHSMAIHMALLGGLGVIHHNCSAEDQANMVRKVKRYENGFILEPVVLSPTTTVAEAKAL 158 Query: 129 KKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTL 188 K+K GF G+P+T+NG L +LIG++TSRDI F + VMT D++TA G TL Sbjct: 159 KEKWGFGGFPVTENGTLPSKLIGMITSRDIQFHPTGED-PVPAVMT--TDLLTAPSGTTL 215 Query: 189 QDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRD 248 +AN + ++ LP + A P+ +KQL+ AAI TR Sbjct: 216 AEANEV-RSHEEPSLPYL-----------------ASKLPH-----SKQLICAAAICTRP 252 Query: 249 TDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLI 308 D+ERL L+ G+D+++LDSSQGNS YQI+MIKY + P + V ++ Sbjct: 253 EDKERLPKLIEAGLDIVILDSSQGNSIYQIEMIKYRTKQLPLLPQV-----------RMV 301 Query: 309 DAGVDALRVGMGSGSICITQEVMACGCP--QATAVYQVASYARHFNVPVIADGGIQSVGH 366 V A V + +++ G P Q AVY +A PV+ + + H Sbjct: 302 SVLVWAAEV------LASHKKLWPSGDPRLQLCAVYPNLLHAS--ESPVLRMAVFRILAH 353 Query: 367 IIKSLALGASTVMMGSLLAGTSEAPGEYFFS-DGVRLKKYRGMGSLEAMESK---DGKG- 421 I+K LA+GA+TVMMG LLAGT+E+PG YF S +G +K YRGMGS++AME K GKG Sbjct: 354 IVKGLAMGATTVMMGGLLAGTTESPGSYFVSREGQLVKAYRGMGSIDAMEDKKAGGGKGG 413 Query: 422 ----SAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477 + +RYF ESD+ VAQGVSGS++D+GSV +F+PYL AG+QHS QD+G +S+ L Sbjct: 414 QANNAGTARYF-SESDRLLVAQGVSGSVLDRGSVTKFVPYLMAGIQHSLQDIGVKSLKEL 472 Query: 478 REMSHSGDLRFMKRTYSAQLEGNVHGLFSYEKRLF 512 + +G +RF R+ SAQ EG VHGL S++K+L+ Sbjct: 473 HDGVAAGTVRFEVRSVSAQAEGGVHGLHSFDKKLY 507 >UniRef50_O67820 Cluster: Inosine-5'-monophosphate dehydrogenase; n=59; cellular organisms|Rep: Inosine-5'-monophosphate dehydrogenase - Aquifex aeolicus Length = 490 Score = 375 bits (923), Expect = e-102 Identities = 207/481 (43%), Positives = 301/481 (62%), Gaps = 15/481 (3%) Query: 23 EGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGG 82 EGLT++D LL+P Y + EVD+++ LTK+I L P+VS MDTVTEA +AI++A GG Sbjct: 10 EGLTFDDVLLVPQYSEVLPHEVDVSTYLTKRIKLNIPIVSAAMDTVTEARLAIALAREGG 69 Query: 83 IGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQN 142 IGIIH N + QA EV KVKK + G I +PV + P+ V + L+ K +G P+ Sbjct: 70 IGIIHRNLPIKKQAEEVEKVKKSESGMIINPVTVKPDTRVKEALDIMAKYKISGVPVVDE 129 Query: 143 GKLGGRLIGIVTSRDIDF-REGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKG 201 + +LIGI+T+RD+ F + D + E MT N +ITA G+TL +A I K K Sbjct: 130 ER---KLIGILTNRDLRFIKPEDYSKPVSEFMTKEN-LITAPEGITLDEAEEIFRKYKIE 185 Query: 202 KLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNG 261 KLPI++ +G++ LI D+ K + YPNA KD +L VGAA+GT + +R+ LV G Sbjct: 186 KLPIVDKEGKIKGLITIKDIVKRKKYPNACKDELGRLRVGAAVGTGEETLDRVAALVEAG 245 Query: 262 VDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGS 321 VDVIV+D++ G+S ++ ++ IK +PE+ V+ GNV T K LI+AG DA++VG+G Sbjct: 246 VDVIVVDTAHGHSKRVLETVEKIKANFPEVDVIAGNVATAEGTKALIEAGADAVKVGVGP 305 Query: 322 GSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMG 381 GSIC T+ V G PQ TA+ + AS AR +++P+IADGGI+ G I+K+LA GAS VM+G Sbjct: 306 GSICTTRIVAGVGVPQLTAIMEAASAAREYDIPIIADGGIRYSGDIVKALAAGASAVMLG 365 Query: 382 SLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGV 441 +LLAGT EAPGE + G K YRGMGSL AM S+ + RY ++ +K V +G+ Sbjct: 366 NLLAGTEEAPGETIYYQGRAYKVYRGMGSLGAMSSR----LSSDRYGQEKMEKF-VPEGI 420 Query: 442 SGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNV 501 G + KG + + L G++ +GAR++ L+E + +F++ T++ E +V Sbjct: 421 EGRVPYKGKLADVVYQLVGGLRSGMGYVGARNIKELQEKA-----KFVRITWAGYRESHV 475 Query: 502 H 502 H Sbjct: 476 H 476 >UniRef50_Q39F71 Cluster: IMP dehydrogenase; n=31; Proteobacteria|Rep: IMP dehydrogenase - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 486 Score = 357 bits (878), Expect = 4e-97 Identities = 191/483 (39%), Positives = 294/483 (60%), Gaps = 19/483 (3%) Query: 23 EGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGG 82 + LT++D LL+P + D + L + LT+ I L PLVS MDTVTE +AI+MA GG Sbjct: 6 KALTFDDVLLVPAFSDVLPRDTSLKTKLTRNISLNMPLVSAAMDTVTEGRLAIAMAQQGG 65 Query: 83 IGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQN 142 +GI+H N TP QA EV KVK+++ G +RDP+ + P+ V DV+ +++G +G+P+ + Sbjct: 66 VGIVHKNLTPAEQAREVAKVKRFESGVVRDPITVPPQMKVRDVIALSRQHGISGFPVVE- 124 Query: 143 GKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGK 202 G +L+GIVT+RD+ F E +K +MTP ++T + G L +A ++ + + Sbjct: 125 ---GPQLVGIVTNRDLRF-ETRLDEPVKSIMTPRERLVTVKEGTPLAEAKALMHSHRLER 180 Query: 203 LPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGV 262 + ++N+ EL L+ D+ K +P+A KD + +L GAA+G + ER++LLV GV Sbjct: 181 VLVVNDAFELRGLMTVKDITKQTEHPDACKDEHGKLRAGAAVGVGPDNEERVELLVQAGV 240 Query: 263 DVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSG 322 DVIV+D++ G+S ++ ++++K+ +P ++V+GGN+ T AK L++ G DA++VG+G G Sbjct: 241 DVIVVDTAHGHSKGVLERVRWVKQNFPHVEVIGGNIATAAAAKALVEYGADAVKVGIGPG 300 Query: 323 SICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGS 382 SIC T+ V G PQ +A+ VA + VP IADGG++ G + K+LA GA+ VMMGS Sbjct: 301 SICTTRIVAGVGVPQISAIANVAEALKGTGVPCIADGGVRFSGDVSKALAAGANAVMMGS 360 Query: 383 LLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKES---DKHRVAQ 439 + AGT EAPG+ F G + K YRGMGS+ AM KDG A RYF S DK V + Sbjct: 361 MFAGTEEAPGDVFLYQGRQYKSYRGMGSVGAM--KDG---AADRYFQDNSANIDK-LVPE 414 Query: 440 GVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEG 499 G+ G + KGSV L L G++ S G +++ L + + F++ T + E Sbjct: 415 GIEGRVAYKGSVNAILFQLVGGVRASMGYCGCKTIDELHDKA-----EFVQITAAGMRES 469 Query: 500 NVH 502 +VH Sbjct: 470 HVH 472 >UniRef50_Q49729 Cluster: Inosine-5'-monophosphate dehydrogenase; n=581; cellular organisms|Rep: Inosine-5'-monophosphate dehydrogenase - Mycobacterium leprae Length = 529 Score = 346 bits (851), Expect = 7e-94 Identities = 193/460 (41%), Positives = 278/460 (60%), Gaps = 9/460 (1%) Query: 24 GLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGGI 83 GLT++D LLLP D D++S LTKKI LK PLVS+ MDTVTEA MAI+MA GG+ Sbjct: 44 GLTFDDVLLLPAASDVVPATADISSQLTKKIRLKVPLVSSAMDTVTEARMAIAMARAGGM 103 Query: 84 GIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNG 143 G++H N QA +V VK+ + G + DPV P+NT+A V + +G P+ + Sbjct: 104 GVLHRNLPVGEQAGQVETVKRSEAGMVTDPVTCRPDNTLAQVGALCARFRISGLPVVDDS 163 Query: 144 KLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKL 203 G L GI+T+RD+ F E D + EVMT +ITA GV+ A +L ++K KL Sbjct: 164 ---GALAGIITNRDMRF-EVDQSKQVAEVMTK-TPLITAAEGVSADAALGLLRRNKIEKL 218 Query: 204 PIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVD 263 P+++ G L LI D K +P A+KD++ +LLVGAA+G R +LV+ GVD Sbjct: 219 PVVDGHGRLTGLITVKDFVKTEQHPLATKDNDGRLLVGAAVGVGGDAWVRAMMLVDAGVD 278 Query: 264 VIVLDSSQGNSTYQIKMIKYIK-ETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSG 322 V+++D++ ++ + M+ +K E +QV+GGNV TR A L++AG DA++VG+G G Sbjct: 279 VLIVDTAHAHNRLVLDMVGKLKVEIGDRVQVIGGNVATRSAAAALVEAGADAVKVGVGPG 338 Query: 323 SICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGS 382 S C T+ V G PQ TA+ + + VPVIADGG+Q G I K+LA GAST M+GS Sbjct: 339 STCTTRVVAGVGAPQITAILEAVAACGPAGVPVIADGGLQYSGDIAKALAAGASTTMLGS 398 Query: 383 LLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDG-KGSAMSRYFHKE--SDKHRVAQ 439 LLAGT+EAPGE F +G + K YRGMGSL AM+ + G K + RYF + S+ V + Sbjct: 399 LLAGTAEAPGELIFVNGKQFKSYRGMGSLGAMQGRGGDKSYSKDRYFADDALSEDKLVPE 458 Query: 440 GVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLRE 479 G+ G + +G + + L G++ + G+ ++ VL++ Sbjct: 459 GIEGRVPFRGPLSSVIHQLVGGLRAAMGYTGSPTIEVLQQ 498 >UniRef50_Q9RT87 Cluster: Inosine-5`-monophosphate dehydrogenase; n=14; cellular organisms|Rep: Inosine-5`-monophosphate dehydrogenase - Deinococcus radiodurans Length = 500 Score = 331 bits (814), Expect = 2e-89 Identities = 194/483 (40%), Positives = 290/483 (60%), Gaps = 20/483 (4%) Query: 23 EGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGG 82 EG+T++D LL P + EVD+++ LT+++ L P VS MDTVTE +MAI+MA GG Sbjct: 25 EGITFDDVLLQPRHSQVLPHEVDVSAQLTRRVRLNIPFVSAAMDTVTETNMAIAMAREGG 84 Query: 83 IGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQN 142 IG++H N + + QA + KVK+ + G I DP+ + P TV D + +G P+T Sbjct: 85 IGVVHKNMSIDAQAEMIRKVKRSESGMIVDPITLPPSATVRDADRLMGEYRISGVPVTAP 144 Query: 143 GKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGK 202 G+L+GI+T+RD+ F + D + L +VMT ++T +G L+ A + + ++ K Sbjct: 145 D---GKLLGIITNRDMRFID-DLDVPLGDVMTR-EHLVTVPVGTDLEQARELFKLNRIEK 199 Query: 203 LPIINNDGE-LVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNG 261 L + +GE L LI D++K+ YPNA+KD +L V AAIG +R LV G Sbjct: 200 LLV--TEGEYLRGLITIKDIEKSVKYPNAAKDDLGRLRVAAAIGVSADLMDRAGALVQAG 257 Query: 262 VDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGS 321 DV+VLDS+ G+S + + +KE + ++ V+ GNV TR A++LI AG DA++VG+G Sbjct: 258 ADVLVLDSAHGHSQGILNALSRVKEQF-DVDVIAGNVATRSGARDLILAGADAVKVGIGP 316 Query: 322 GSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMG 381 GSIC T+ V G PQ TA+++ ++ A +PVIADGGI+ G + K++A GAS VMMG Sbjct: 317 GSICTTRVVTGVGVPQVTAIFEASAAAMEAGIPVIADGGIKQTGDVPKAIAAGASVVMMG 376 Query: 382 SLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGV 441 S+LAGT EAPGE DG R K YRGMGSL AM+ +GSA RYF S K V +G+ Sbjct: 377 SMLAGTDEAPGETILRDGRRYKSYRGMGSLGAMD----QGSA-DRYFQGGSRKF-VPEGI 430 Query: 442 SGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNV 501 G I +G+ + G++ S GA ++ LR+ + +F++ T ++ +E + Sbjct: 431 EGIIAYRGTAGEVIYQFVGGLKSSMGYCGAPDLTTLRDTA-----QFVRITGASLVESHP 485 Query: 502 HGL 504 HG+ Sbjct: 486 HGV 488 >UniRef50_A7DPR0 Cluster: Inosine-5'-monophosphate dehydrogenase; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Inosine-5'-monophosphate dehydrogenase - Candidatus Nitrosopumilus maritimus SCM1 Length = 476 Score = 331 bits (814), Expect = 2e-89 Identities = 183/459 (39%), Positives = 273/459 (59%), Gaps = 12/459 (2%) Query: 23 EGLTYNDFLLLPGYIDFTAE-EVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCG 81 EGLT++D LL+P Y D T+ + DLT+ L++ I + P VS MDTVTE+ MA++MA G Sbjct: 5 EGLTFDDVLLVPKYSDITSRSQTDLTTKLSRNITINIPFVSANMDTVTESSMAVAMARAG 64 Query: 82 GIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQ 141 GIGIIH T + QANEV KVK+ I +P + + ++ D L+ + +G + Sbjct: 65 GIGIIHRFLTIQEQANEVLKVKRSGSVMIENPYSISSDKSIQDALDYAEDKEISGLLVVD 124 Query: 142 NGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKG 201 + +L+GIVT RD+ F + ++ +VMT D++TA+ GV+L +A IL K + Sbjct: 125 SNS---KLVGIVTERDLLFAGSNG--TIADVMT--KDVVTAKPGVSLDEAKDILHKHRIE 177 Query: 202 KLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNG 261 KLPI+++ G + LI D+ YPNASKD + LVGAA+G + ER + L+N G Sbjct: 178 KLPIVDDSGIIQGLITSKDITNNTDYPNASKDKKGRPLVGAAVGVKGDFLERSESLLNAG 237 Query: 262 VDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGS 321 DV+V+D + G+S I ++ IK+ +P+ +++ GN+ T A++LI AGVDA++VG+GS Sbjct: 238 ADVLVVDIAHGHSENAISTVRNIKKAFPDCELIAGNIATAQGAEDLIKAGVDAVKVGVGS 297 Query: 322 GSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMG 381 GSICIT+ + G PQ TAV A +P+I+DGG ++ G K+LA GAS+VM+G Sbjct: 298 GSICITRVITGSGVPQLTAVMDCAKIGNDHGIPIISDGGTRTSGDATKALAAGASSVMVG 357 Query: 382 SLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESD-KHRVAQG 440 S+L GT E+PG +G R K YRGM SL A G+ S + E D VA+G Sbjct: 358 SMLGGTDESPGTVLTKNGKRFKVYRGMASLAA---SIGRKSKETGSISLEDDLNDYVAEG 414 Query: 441 VSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLRE 479 V + KG+V L L G++ GA ++ +++ Sbjct: 415 VEAMVPYKGTVTDILKQLAGGVRSGLSYCGAHTIPQMQQ 453 >UniRef50_P0ADG9 Cluster: Inosine-5'-monophosphate dehydrogenase; n=14; Gammaproteobacteria|Rep: Inosine-5'-monophosphate dehydrogenase - Shigella flexneri Length = 488 Score = 325 bits (799), Expect = 1e-87 Identities = 184/458 (40%), Positives = 267/458 (58%), Gaps = 12/458 (2%) Query: 23 EGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGG 82 E LT++D LL+P + DL++ LTK I L P++S MDTVTEA +AI++A GG Sbjct: 7 EALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIALAQEGG 66 Query: 83 IGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQN 142 IG IH N + E QA EV +VKK++ G + DP + P T+ +V E ++NGF GYP+ Sbjct: 67 IGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLREVKELTERNGFAGYPVVTE 126 Query: 143 GKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGK 202 L+GI+T RD+ F D + + MTP ++T + G + + + + K Sbjct: 127 EN---ELVGIITGRDVRFVT-DLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRVEK 182 Query: 203 LPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGV 262 +++++ L+ +I D +KA PNA KD +L VGAA+G + ER+ LV GV Sbjct: 183 ALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRLRVGAAVGAGAGNEERVDALVAAGV 242 Query: 263 DVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSG 322 DV+++DSS G+S ++ I+ + YP++Q++GGNV T A+ L +AG A++VG+G G Sbjct: 243 DVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVATAAGARALAEAGCSAVKVGIGPG 302 Query: 323 SICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGS 382 SIC T+ V G PQ TAV +PVIADGGI+ G I K++A GAS VM+GS Sbjct: 303 SICTTRIVTGVGVPQITAVADAVEALEGTGIPVIADGGIRFSGDIAKAIAAGASAVMVGS 362 Query: 383 LLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHR-VAQGV 441 +LAGT E+PGE G K YRGMGSL AM KGS+ RYF ++ + V +G+ Sbjct: 363 MLAGTEESPGEIELYQGRSYKSYRGMGSLGAM----SKGSS-DRYFQSDNAADKLVPEGI 417 Query: 442 SGSIVDKGSVLRFLPYLQAGMQHSCQDL-GARSVSVLR 478 G + KG L+ + + Q G SC L G ++ LR Sbjct: 418 EGRVAYKGR-LKEIIHQQMGGLRSCMGLTGCGTIDELR 454 >UniRef50_Q59011 Cluster: Inosine-5'-monophosphate dehydrogenase; n=15; Euryarchaeota|Rep: Inosine-5'-monophosphate dehydrogenase - Methanococcus jannaschii Length = 496 Score = 313 bits (768), Expect = 8e-84 Identities = 181/486 (37%), Positives = 283/486 (58%), Gaps = 23/486 (4%) Query: 26 TYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGGIGI 85 T++D LL+P ++ D+++ L + L P+VS MDTVTE +MAI++A GG+G+ Sbjct: 14 TFDDVLLVPNASWVEPKDTDVSTDLAG-LKLNIPIVSAAMDTVTEKEMAIALARLGGLGV 72 Query: 86 IHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKL 145 IH N + E Q ++V VKK I+D + + P++TV + + + +G P+ N Sbjct: 73 IHRNMSIEEQVHQVQAVKKADEVVIKDVITVSPDDTVGEAINVMETYSISGLPVVDNED- 131 Query: 146 GGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPI 205 +L+GI+T RD+ E D +K+VMT D++ A+ V ++A ++ ++ +LPI Sbjct: 132 --KLVGIITHRDVKAIE-DKTKKVKDVMT--KDVVCAKEDVEEEEALELMYANRVERLPI 186 Query: 206 INNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVI 265 ++++ L+ +I D+ K R YP A++D +LLV AA G D ER K L+ VD I Sbjct: 187 VDDENRLIGIITLRDILKRRKYPQAARDKKGRLLVAAACGPHDF--ERAKALIEAEVDAI 244 Query: 266 VLDSSQGNSTYQIKMIKYIKETYP--EIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGS 323 +D + ++ ++ +K KE +I+++ GN+ T+ A++LI AG D L+VG+G GS Sbjct: 245 AIDCAHAHNMRVVENVKKFKEMLEGTDIKLIVGNIATKEAAEDLIKAGADVLKVGIGPGS 304 Query: 324 ICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSL 383 IC T+ V G PQ TAV +VA A+ NVP+IADGGI+ G I K++A GA VM+GSL Sbjct: 305 ICTTRVVAGVGVPQLTAVAEVADVAKEHNVPIIADGGIRYSGDIAKAIAAGADAVMLGSL 364 Query: 384 LAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHR-----VA 438 LAGT EAPG+ +G + K+YRGMGSL AM G G+ RYF + H V Sbjct: 365 LAGTDEAPGQLMVINGRKYKQYRGMGSLGAMTG--GVGAGADRYFQAPAKSHMKHVKLVP 422 Query: 439 QGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLE 498 +GV G++ KG V + L G++ S GA+++ ++E + RF+ T S Q+E Sbjct: 423 EGVEGAVPYKGPVSEVVFQLIGGLRASMGYCGAKNLKEMQEKA-----RFVIITPSGQVE 477 Query: 499 GNVHGL 504 + H + Sbjct: 478 SHPHDI 483 >UniRef50_A6DTA2 Cluster: Inosine-5'-monophosphate dehydrogenase; n=2; Lentisphaerae|Rep: Inosine-5'-monophosphate dehydrogenase - Lentisphaera araneosa HTCC2155 Length = 500 Score = 305 bits (750), Expect = 1e-81 Identities = 192/464 (41%), Positives = 264/464 (56%), Gaps = 19/464 (4%) Query: 23 EGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGG 82 +GLT++D L+ Y DF EE + S ++ I L P VS MDTVT MAI++A GG Sbjct: 17 QGLTFDDVTLVTQYADFLPEETSIKSKFSRNIGLNIPFVSAAMDTVTGPSMAIAIARLGG 76 Query: 83 IGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAK--KKNGFTGYPIT 140 IG+IH N A V KVK + +G I+DPV TV ++L K K+ F+G+PI Sbjct: 77 IGVIHKNMDIALHAEAVKKVKLHSNGLIQDPVSFQESQTVEELLNYKDEKRLPFSGFPIV 136 Query: 141 QNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKK 200 GR+ GI+T++D+ F D L LK+VMT + ++TA G TL+DA I+ K Sbjct: 137 D---ANGRVAGILTAKDLKFC-NDSRLKLKDVMT--SSILTANEGTTLEDAYKIMIDKKI 190 Query: 201 GKLPIINNDGELVALIARTDLKKARSYPN--ASKDSNKQLLVGAAIGTRDTDRERLKLLV 258 GKLP++ +G L L + D+ + + + DS QL AAI D R + L+ Sbjct: 191 GKLPLLCENGSLAGLYSFHDVNALITGTSKLENLDSKYQLRCAAAISPYDFG--RAEALI 248 Query: 259 NNGVDVIVLDSSQGNSTYQIKMIKYIKETY-PEIQVVGGNVVTRMQAKNLIDAGVDALRV 317 N GVD IV+D++ G+S I+ +K +K + V+ GNV T + AK L DAG DA++V Sbjct: 249 NAGVDAIVIDTAHGHSKGVIETVKELKAGMGSSVDVIAGNVGTAVGAKALADAGADAVKV 308 Query: 318 GMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGAST 377 G+G GSIC T+ V G PQ TAVY+ AS A +VP+IADGGI+ G + K++ GAS+ Sbjct: 309 GIGPGSICTTRVVCGVGVPQITAVYE-ASRAVPSDVPIIADGGIKQSGDVPKAITSGASS 367 Query: 378 VMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH--KESDKH 435 VMMG LLA T E+PGE G R YRGMGSLEAM K GKGS RY E Sbjct: 368 VMMGGLLAATEESPGEKIMMQGRRFVVYRGMGSLEAM--KSGKGS-RERYSQGDVEDSSQ 424 Query: 436 RVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLRE 479 + QGV G + +G+ L ++ S GA++V L++ Sbjct: 425 LIPQGVEGRVPYRGTAGSVLHQFAGSLKFSLGYCGAKTVPELQQ 468 >UniRef50_Q4QEB3 Cluster: Inosine-5'-monophosphate dehydrogenase; n=7; cellular organisms|Rep: Inosine-5'-monophosphate dehydrogenase - Leishmania major Length = 553 Score = 294 bits (722), Expect = 3e-78 Identities = 176/490 (35%), Positives = 274/490 (55%), Gaps = 20/490 (4%) Query: 23 EGLTYNDFLLLPGYIDFTAEE-VDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCG 81 EGLTY+D LL+P + + V+ ++ L++ I LK P+V++ MDTV E A++MA G Sbjct: 73 EGLTYDDVLLIPQRSPVRSRKAVNTSTRLSRNIHLKIPIVASNMDTVCEDKTAVTMAREG 132 Query: 82 GIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYP--- 138 GIGI+H C+ E Q V KVK+ + I DP + P T A+ LE +G G Sbjct: 133 GIGILHRFCSIEEQCAMVRKVKRAQSFLIEDPRMILPSATKAEALEELNWSGRKGGVSCL 192 Query: 139 ITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITA-QLGVTLQDANYILEK 197 + + RL G++T D+ F G ++ +MTP++ M+ + +TL++A ++ Sbjct: 193 MVVDDLTSRRLCGVLTKSDLTFATGSA--LVETLMTPVSRMVVSTNTAITLEEAREVMRT 250 Query: 198 SKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLL 257 + +P++ GEL+ LI R+D+ K NA+ DS +L+VGAAIG + D ER L Sbjct: 251 KRTKNIPLLGPKGELLYLITRSDILKLTGNLNATLDSRGRLIVGAAIGVKKEDHERAAAL 310 Query: 258 VNNGVDVIVLDSSQGNSTYQIKMIKYIKET--YPEIQVVGGNVVTRMQAKNLIDAGVDAL 315 V+ G DV+V+D + G+S I M+K +K ++ ++ GN+ T A++LIDAG D L Sbjct: 311 VDAGADVLVVDIAHGHSDLCIDMVKALKVNPLTNKVDIIAGNIATAEAAQDLIDAGADGL 370 Query: 316 RVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGA 375 ++G+G GSICIT+ V G PQ ++V A A+ VP IADGGI++ G I K++A GA Sbjct: 371 KIGVGPGSICITRLVAGSGVPQLSSVMDCARVAKKHGVPCIADGGIKTAGDICKAIAAGA 430 Query: 376 STVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSR-YFHKESDK 434 TVM+G++LAGT EAPG DG ++K RGM A SK + + FH Sbjct: 431 DTVMLGNMLAGTDEAPGRVLVKDGKKVKIIRGMAGFGANISKAEREQRLDEDVFH----- 485 Query: 435 HRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYS 494 V +GV GS+ KG + L L G++ G+ S++ +++ + RF++ + + Sbjct: 486 DLVPEGVEGSVPCKGPLAPILKQLVGGLRSGISYCGSHSIADMQQRA-----RFVRMSGA 540 Query: 495 AQLEGNVHGL 504 E H + Sbjct: 541 GLRESGSHDI 550 >UniRef50_Q4PBE7 Cluster: Putative uncharacterized protein; n=2; Fungi/Metazoa group|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 247 Score = 281 bits (690), Expect = 2e-74 Identities = 155/253 (61%), Positives = 181/253 (71%), Gaps = 28/253 (11%) Query: 280 MIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQAT 339 MI++IK+TYP+I VV GNVVTR QA +LI AG DALRVGMGSGSICITQEVMA G PQ T Sbjct: 1 MIQWIKQTYPQIDVVAGNVVTREQAASLIAAGADALRVGMGSGSICITQEVMAVGRPQGT 60 Query: 340 AVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDG 399 AV+ F VPVIADGGI +VGHI K+LALGAS VMMG LLAGT+E+PG+YF+ DG Sbjct: 61 AVHA-------FGVPVIADGGISNVGHIAKALALGASAVMMGGLLAGTTESPGDYFYRDG 113 Query: 400 VRLKKYRGMGSLEAMESK--------DGKGSAMS------------RYFHKESDKHRVAQ 439 RLK YRGMGS+EAME + GKG+A + RYF ESD +VAQ Sbjct: 114 KRLKGYRGMGSIEAMEHQKKGKIAGATGKGAAKADKVATDENAATQRYF-SESDAVKVAQ 172 Query: 440 GVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEG 499 GV+G++ DKGSV +FLPYL G+QHS QD+G + LR SG +RF RT SAQ+EG Sbjct: 173 GVAGAVQDKGSVKKFLPYLYTGLQHSLQDMGVPHLYQLRSAVASGQVRFELRTASAQVEG 232 Query: 500 NVHGLFSYEKRLF 512 VHGL SYEKRLF Sbjct: 233 GVHGLHSYEKRLF 245 >UniRef50_Q0DN24 Cluster: Os03g0780500 protein; n=7; Magnoliophyta|Rep: Os03g0780500 protein - Oryza sativa subsp. japonica (Rice) Length = 220 Score = 265 bits (650), Expect = 2e-69 Identities = 136/225 (60%), Positives = 168/225 (74%), Gaps = 6/225 (2%) Query: 288 YPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASY 347 YPE+ ++GGNVVT QA+NL+ +GVD LRVGMGSGSIC TQEV A G QATAVY+VASY Sbjct: 2 YPEVDLIGGNVVTIAQAQNLVASGVDGLRVGMGSGSICTTQEVCAVGRGQATAVYKVASY 61 Query: 348 ARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRG 407 A+ NVPVIADGGI + GHI+K+L+LGASTVMMGS LAG+ EAPG Y + DG R+KKYRG Sbjct: 62 AKDHNVPVIADGGISNSGHIVKALSLGASTVMMGSFLAGSHEAPGTYEYKDGHRVKKYRG 121 Query: 408 MGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQ 467 MGSLEAM KGS +RY ++ K +VAQGV G++ DKGSVLRF+PY ++ Q Sbjct: 122 MGSLEAMT----KGSD-ARYL-GDTLKLKVAQGVVGAVADKGSVLRFIPYTMQAVKQGFQ 175 Query: 468 DLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNVHGLFSYEKRLF 512 DLGA S+ E+ S ++ RT +AQ+EG +HGL SYEK+ F Sbjct: 176 DLGASSLQSAHELLRSETIKLEVRTGAAQVEGGIHGLVSYEKKAF 220 >UniRef50_A7CYS7 Cluster: Malate dehydrogenase precursor; n=1; Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase precursor - Opitutaceae bacterium TAV2 Length = 564 Score = 256 bits (626), Expect = 1e-66 Identities = 167/479 (34%), Positives = 264/479 (55%), Gaps = 35/479 (7%) Query: 24 GLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGGI 83 GLT++D L Y D ++ D ++ L+ + L P++S+ MDTVTE MAI+MAL GG+ Sbjct: 69 GLTFDDVSLATLYSDILPKDADTSTSLSDALKLSIPIISSDMDTVTEERMAIAMALNGGL 128 Query: 84 GIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEA--KKKNGFTGYPITQ 141 G+IH+N Q V +VK++ HG I+DP+ + P VADVL+ K+ F +P+ Sbjct: 129 GLIHYNMPARDQVKAVARVKRHIHGLIQDPITVTPNQYVADVLDLVEHKRYDFRTFPVVD 188 Query: 142 NGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITA---QLG---VTLQDANYIL 195 G+L+G+++ + RE ++ E M+P ++ T QL + DA + Sbjct: 189 EH---GKLVGLLSGSSV--RERYKGKTVAEAMSPRGEIQTLHERQLQPDPIKAADA-FFT 242 Query: 196 EKSKKGKLPIINNDGELVALIARTD----LKKARSYPNASKDSNKQLLVGAAI------- 244 E K+ +++++ L L+ +D L+++RS ++D +L+VGAAI Sbjct: 243 EHIGIHKMLVVDDNDRLRGLVTFSDIDSILQESRSRRKPARDHAFRLVVGAAIAPVRHPD 302 Query: 245 GTRDTDR--ERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRM 302 GT D D+ + LV+ +D + + ++ G++T M+K ++ +P + ++ GNV + Sbjct: 303 GTLDRDKIISHVGHLVDESIDAVAVSTAHGHTTGVGDMVKLVRAAFPNLTIIAGNVTSGA 362 Query: 303 QAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQ 362 + L D G +A++VG G GSIC T+ V G PQ TA+Y + AR N+ +IADGGI Sbjct: 363 GVEFLADCGANAIKVGQGPGSICTTRIVAGVGIPQLTALYVASRAARGKNIKIIADGGIT 422 Query: 363 SVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGS 422 G I+K+L LG V++G LLAG EAPGE +G K+YRGMGSL AM + GS Sbjct: 423 KSGDIVKALTLG-DAVILGGLLAGCREAPGEIIDINGKLYKQYRGMGSLSAMNA----GS 477 Query: 423 AMSRYFHKESDKHR--VAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLRE 479 A +RY H ++D R A+G+ GS L L G+Q LG++ + LR+ Sbjct: 478 A-ARYGHDKTDTTRKLTAEGIEALKEVSGSADDVLATLVGGVQSGMGYLGSKDLPTLRQ 535 >UniRef50_Q8EW89 Cluster: Inosine-5'-monophosphate dehydrogenase; n=1; Mycoplasma penetrans|Rep: Inosine-5'-monophosphate dehydrogenase - Mycoplasma penetrans Length = 483 Score = 252 bits (617), Expect = 2e-65 Identities = 153/481 (31%), Positives = 269/481 (55%), Gaps = 17/481 (3%) Query: 25 LTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGGIG 84 LT++D LL P Y + +E D+ + L+ + +K P++S MDTVTE +MA +M+L GGIG Sbjct: 11 LTFDDVLLRPQYSEVLPKETDVRTTLSSRFQMKIPIMSASMDTVTEIEMAYNMSLNGGIG 70 Query: 85 IIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGK 144 +IH N + Q+N + ++K K+G + + N ++ + E K + + I Sbjct: 71 VIHKNLSHSQQSNMIKQIKHIKNGLYYNIMAFESSNKISMIKE-KVFDEYLDDCIFVT-- 127 Query: 145 LGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLP 204 + G ++ IV+ D++ ++ D + +L+ + +I A+ +L++ I++++K +P Sbjct: 128 VNGSIVNIVSKEDLENKKIDSNSTLESIGR--KKIIFAKDSSSLEEILKIMDENKLDFMP 185 Query: 205 IINNDGE-LVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVD 263 I++ ++A+ R L + + DS ++ V AIG + ER KLL+ GVD Sbjct: 186 IVSETTNGIIAVAKRKWLVPYLNSDDPLIDSKERPKVCGAIGVTEDSIERAKLLIAAGVD 245 Query: 264 VIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGS 323 I++D + G+S I++ + IK+ +P++ ++ GNVVT +L AG DA+++G+G G+ Sbjct: 246 AIIIDCAHGHSKKVIELTREIKKLFPKLFLIVGNVVTANGVNDLYKAGADAVKIGVGPGA 305 Query: 324 ICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSL 383 IC T+ V G PQ +A+ + A+ N+P+IADGGI++ G ++K+LA GA VM+GSL Sbjct: 306 ICTTRTVSGVGIPQFSAILECYEEAKKLNIPIIADGGIKNSGDMVKALAAGADAVMLGSL 365 Query: 384 LAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGVSG 443 LAG E+P + K+YRGMGS+ AM K + RY ++ K VA+GV G Sbjct: 366 LAGCDESPSVKVMHNNKMYKQYRGMGSIAAM-----KAGSSDRY-GQDGIKKLVAEGVEG 419 Query: 444 SIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNVHG 503 + G V L L G++ +GA++++ L+ + F+++T E + H Sbjct: 420 LMPYIGPVKESLYQLVGGLKSGMGYVGAKTLTDLKNKA-----EFVEQTGIGLKESSTHS 474 Query: 504 L 504 + Sbjct: 475 I 475 >UniRef50_P50097 Cluster: Inosine-5'-monophosphate dehydrogenase; n=28; cellular organisms|Rep: Inosine-5'-monophosphate dehydrogenase - Tritrichomonas foetus (Trichomonas foetus) Length = 503 Score = 240 bits (587), Expect = 7e-62 Identities = 152/404 (37%), Positives = 223/404 (55%), Gaps = 17/404 (4%) Query: 26 TYNDFLLLPGY--IDFTAEEVDLTSPLTK-------KILLKAPLVSTPMDTVTEADMAIS 76 T+N++LL+PG +D V+L++PL K +I LK PLVS M +V+ MAI+ Sbjct: 11 TFNEYLLIPGLSTVDCIPSNVNLSTPLVKFQKGQQSEINLKIPLVSAIMQSVSGEKMAIA 70 Query: 77 MALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTG 136 +A GGI I + + E QA VH VK +K GF+ + P+ T ADVL ++ Sbjct: 71 LAREGGISFIFGSQSIESQAAMVHAVKNFKAGFVVSDSNVKPDQTFADVLAISQRTTHNT 130 Query: 137 YPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILE 196 +T +G G L+G+VT RD + ++MTP + ++TA L +AN I+ Sbjct: 131 VAVTDDGTPHGVLLGLVTQRDYPIDLTQTETKVSDMMTPFSKLVTAHQDTKLSEANKIIW 190 Query: 197 KSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKL 256 + K LPII++D L ++ R D +++ N DS K+ LVGA I TRD RER+ Sbjct: 191 EKKLNALPIIDDDQHLRYIVFRKDYDRSQVCHNELVDSQKRYLVGAGINTRDF-RERVPA 249 Query: 257 LVNNGVDVIVLDSSQGNSTYQIKMIKYIKETY-PEIQVVGGNVVTRMQAKNLIDAGVDAL 315 LV G DV+ +DSS G S +Q I +I+E Y +++V GN+V + L DAG D + Sbjct: 250 LVEAGADVLCIDSSDGFSEWQKITIGWIREKYGDKVKVGAGNIVDGEGFRYLADAGADFI 309 Query: 316 RVGMGSGSICITQEVMACGCPQATAVYQ-VASYARHFN-----VPVIADGGIQSVGHIIK 369 ++G+G GSICIT+E G QATAV VA ++F +PV +DGGI H+ Sbjct: 310 KIGIGGGSICITREQKGIGRGQATAVIDVVAERNKYFEETGIYIPVCSDGGIVYDYHMTL 369 Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEA 413 +LA+GA +M+G A E+P +G +K+Y G GS A Sbjct: 370 ALAMGADFIMLGRYFARFEESPTRKVTINGSVMKEYWGEGSSRA 413 >UniRef50_Q08MB8 Cluster: Inosine-5'-monophosphate dehydrogenase; n=1; Stigmatella aurantiaca DW4/3-1|Rep: Inosine-5'-monophosphate dehydrogenase - Stigmatella aurantiaca DW4/3-1 Length = 344 Score = 223 bits (545), Expect = 9e-57 Identities = 125/293 (42%), Positives = 188/293 (64%), Gaps = 9/293 (3%) Query: 25 LTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGGIG 84 LT++D LLLP +V+L++ LT+++ L PL+S MDTVTE+ AI+MA GGIG Sbjct: 46 LTFDDVLLLPAESSVVPRDVELSTRLTRQLRLHIPLLSAAMDTVTESRSAIAMAQEGGIG 105 Query: 85 IIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGK 144 +IH N TPE QA EV KVKK++ G + DPV + P +A LE + +G +G P+TQ Sbjct: 106 VIHKNMTPEQQALEVLKVKKFESGMVVDPVTIEPGAPLARALELMRHHGVSGVPVTQ--- 162 Query: 145 LGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLP 204 G RL+GIVTSRD+ F E + +++VMT +IT + G+T +A +L + + KL Sbjct: 163 -GRRLVGIVTSRDVRF-ETNLTQKVEQVMT--RKLITGREGITQPEAQALLHQHRIEKLL 218 Query: 205 IINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRE-RLKLLVNNGVD 263 I+N + EL LI D++K R++PNA+KD+ +LL AA+G DRE R+ LV GVD Sbjct: 219 IVNEEFELKGLITIKDIEKRRTHPNAAKDAKGRLLCAAAVGV-SADREARIDALVKAGVD 277 Query: 264 VIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALR 316 VIV+D++ G+S + I ++ ++ + +++ GNV T + LI+AGVDA++ Sbjct: 278 VIVVDTAHGHSRFVIDGVRDTRKNFKGFELIAGNVATAEGTRALIEAGVDAVK 330 >UniRef50_UPI00015B43E8 Cluster: PREDICTED: similar to GA14756-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA14756-PA - Nasonia vitripennis Length = 240 Score = 218 bits (533), Expect = 2e-55 Identities = 98/128 (76%), Positives = 115/128 (89%) Query: 385 AGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGVSGS 444 AGTSEAPGEYFFSDGVRLKKYRGMGS+EAM+ KD GSAM RYFH E DK +VAQGVSGS Sbjct: 113 AGTSEAPGEYFFSDGVRLKKYRGMGSIEAMDRKDASGSAMDRYFHNEMDKLKVAQGVSGS 172 Query: 445 IVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNVHGL 504 IVDKG+VL+FLPYLQ G++H CQD+GA+S++ L++M ++G+LRF KRT+SAQ EGNVHGL Sbjct: 173 IVDKGTVLKFLPYLQCGIKHGCQDIGAKSITALKQMMYNGELRFEKRTHSAQQEGNVHGL 232 Query: 505 FSYEKRLF 512 FSYEKRLF Sbjct: 233 FSYEKRLF 240 Score = 171 bits (417), Expect = 3e-41 Identities = 77/91 (84%), Positives = 85/91 (93%) Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70 DGL+A FAN +GLTYNDF++LPGYIDFTA+EVDL SPLTKKI LKAPLVS+PMDTVTE Sbjct: 20 DGLTAAQLFANGDGLTYNDFIILPGYIDFTADEVDLHSPLTKKITLKAPLVSSPMDTVTE 79 Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHK 101 +DMAI+MALCGGIGIIHHNCTPEYQANEVHK Sbjct: 80 SDMAIAMALCGGIGIIHHNCTPEYQANEVHK 110 >UniRef50_P49058 Cluster: Inosine-5'-monophosphate dehydrogenase; n=7; cellular organisms|Rep: Inosine-5'-monophosphate dehydrogenase - Borrelia burgdorferi (Lyme disease spirochete) Length = 404 Score = 205 bits (500), Expect = 2e-51 Identities = 113/282 (40%), Positives = 169/282 (59%), Gaps = 12/282 (4%) Query: 227 YPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKE 286 +PNA KD N +L VGAA+ ER++ LV VD++V+DS+ G+ST I++IK IK Sbjct: 131 FPNACKDLNNKLRVGAAVSIDIDTIERVEELVKAHVDILVIDSAHGHSTRIIELIKKIKT 190 Query: 287 TYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVAS 346 YP + ++ GN+VT+ A +LI G D L+VG+G GSIC T+ V G PQ TA+ V Sbjct: 191 KYPNLDLIAGNIVTKEAALDLISVGADCLKVGIGPGSICTTRIVAGVGVPQITAICDVYE 250 Query: 347 YARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYR 406 + N+ +IADGGI+ G ++K++A GA +VM+G+L AGT E+P E +G + K Y Sbjct: 251 ACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLFAGTKESPSEEIIYNGKKFKSYV 310 Query: 407 GMGSLEAMESKDGKGSAMSRYFHKESD--KHRVAQGVSGSIVDKGSVLRFLPYLQAGMQH 464 GMGS+ AM K + SRYF E++ K V +G+ G + G + L L+ G+ Sbjct: 311 GMGSISAM-----KRGSKSRYFQLENNEPKKLVPEGIEGMVPYSGKLKDILTQLKGGLMS 365 Query: 465 SCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNVHGLFS 506 LGA ++S L+ S +F+K ++S+ E + H +FS Sbjct: 366 GMGYLGAATISDLKINS-----KFVKISHSSLKESHPHDVFS 402 Score = 81.4 bits (192), Expect = 5e-14 Identities = 42/84 (50%), Positives = 53/84 (63%) Query: 23 EGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGG 82 E LT++D L+P EV L + LTK I L P +S+ MDTVTE+ MAI++A GG Sbjct: 8 EALTFDDVSLIPRKSSVLPSEVSLKTQLTKNISLNIPFLSSAMDTVTESQMAIAIAKEGG 67 Query: 83 IGIIHHNCTPEYQANEVHKVKKYK 106 IGIIH N + E Q E+ KVK YK Sbjct: 68 IGIIHKNMSIEAQRKEIEKVKTYK 91 >UniRef50_Q74LZ0 Cluster: Inosine-5-monophosphate dehydrogenase; n=20; Bacteria|Rep: Inosine-5-monophosphate dehydrogenase - Lactobacillus johnsonii Length = 384 Score = 189 bits (461), Expect = 1e-46 Identities = 102/299 (34%), Positives = 165/299 (55%), Gaps = 5/299 (1%) Query: 187 TLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSY----PNASKDSNKQLLVGA 242 T+ + N + ++ G L +I+ + + + K ++ P+ + D +LL A Sbjct: 55 TVTEGNMAIAMAENGGLGVIHKNLSIEVQVEEVKKAKGKTVDPNLPHPAVDDQGRLLAAA 114 Query: 243 AIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRM 302 A+G ER + L+ G D IV+D++ G+S ++ IK I+E +P ++ GNV T Sbjct: 115 AVGVTSDTFERAESLLEAGADAIVIDTAHGHSAGVLRKIKEIREHFPNATLIAGNVATGE 174 Query: 303 QAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQ 362 L DAGVD ++VG+G GSIC T+ V G PQ TA+Y AS A+ + +IADGGI+ Sbjct: 175 GTAALFDAGVDVVKVGIGPGSICTTRIVAGVGVPQITAIYDAASVAQKYGKKIIADGGIK 234 Query: 363 SVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGS 422 G ++K+LA G + VM+GS+ +GT+EAPG F ++G + K YRGMG++ AM + G Sbjct: 235 YSGDVVKALAAGGNAVMLGSMFSGTTEAPGTIFTNEGKQFKSYRGMGAVGAMSQQHGSSD 294 Query: 423 AMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMS 481 + E++K V +GV + KG V + + G++ +GA ++ L E S Sbjct: 295 RYFQGGVNEANK-LVPEGVEALVPYKGDVSNIIYQIDGGLRAGMGYVGAGTIKELIENS 352 Score = 76.6 bits (180), Expect = 1e-12 Identities = 41/88 (46%), Positives = 53/88 (60%), Gaps = 1/88 (1%) Query: 16 EDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAI 75 E FA +GLT++D LL+P EV L + L + L PL+S MDTVTE +MAI Sbjct: 5 ETKFAK-KGLTFDDVLLIPAESHVLPNEVKLDTKLAPNLQLHIPLISAGMDTVTEGNMAI 63 Query: 76 SMALCGGIGIIHHNCTPEYQANEVHKVK 103 +MA GG+G+IH N + E Q EV K K Sbjct: 64 AMAENGGLGVIHKNLSIEVQVEEVKKAK 91 >UniRef50_P65172 Cluster: Uncharacterized oxidoreductase Rv1843c/MT1891; n=42; Bacteria|Rep: Uncharacterized oxidoreductase Rv1843c/MT1891 - Mycobacterium tuberculosis Length = 479 Score = 170 bits (413), Expect = 9e-41 Identities = 130/462 (28%), Positives = 227/462 (49%), Gaps = 15/462 (3%) Query: 25 LTYNDFLLLPGYIDFTAE-EVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGGI 83 LTYND ++P + + +VDL++ + P+V M V MA ++A GGI Sbjct: 14 LTYNDVFIVPNRSEVASRFDVDLSTADGSGTTI--PVVVANMTAVAGRRMAETVARRGGI 71 Query: 84 GIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNG 143 I+ + P + K + + PV + P+++V+D + K G + Sbjct: 72 VILPQDL-PIPAVKQTVAFVKSRDLVLDTPVTLAPDDSVSDAMALIHKRAH-GVAVVI-- 127 Query: 144 KLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKL 203 L GR IG+V R+ D ++++ + D +TA G + +LE + Sbjct: 128 -LEGRPIGLV--RESSCLGVDRFTRVRDIA--VTDYVTAPAGTEPRKIFDLLEHAPVDVA 182 Query: 204 PIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVD 263 + + DG L +++RT +A Y A+ DS +L +GAA+G + + L GVD Sbjct: 183 VLTDADGTLAGVLSRTGAIRAGIYTPAT-DSAGRLRIGAAVGINGDVGAKARALAEAGVD 241 Query: 264 VIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGS 323 V+V+D++ G+ + IK + + + GNVV+ ++L+ AG + ++VG+G G+ Sbjct: 242 VLVIDTAHGHQVKTLDAIKAVSALDLGLPLAAGNVVSAEGTRDLLKAGANVVKVGVGPGA 301 Query: 324 ICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSL 383 +C T+ + G PQ +AV + AS AR + ADGGI+ + +LA GAS VM+GS Sbjct: 302 MCTTRMMTGVGRPQFSAVLECASAARQLGGHIWADGGIRHPRDVALALAAGASNVMIGSW 361 Query: 384 LAGTSEAPGEYFFS-DGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGVS 442 AGT E+PG+ D K+ GM S A+ ++ G + R K + ++ Sbjct: 362 FAGTYESPGDLMRDRDDQPYKESYGMASKRAVVARTGADNPFDR-ARKALFEEGISTSRM 420 Query: 443 GSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSG 484 G D+G V + ++ +G++ +C +GA +++ L E + G Sbjct: 421 GLDPDRGGVEDLIDHITSGVRSTCTYVGASNLAELHERAVVG 462 >UniRef50_A3H9U2 Cluster: IMP dehydrogenase; n=1; Caldivirga maquilingensis IC-167|Rep: IMP dehydrogenase - Caldivirga maquilingensis IC-167 Length = 491 Score = 167 bits (407), Expect = 5e-40 Identities = 139/486 (28%), Positives = 225/486 (46%), Gaps = 37/486 (7%) Query: 25 LTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGGIG 84 +T+ND +LLPG +D ++ +++ + + PLVS+PMDTVTE +AI++A GG+G Sbjct: 33 VTFNDVVLLPGKATLDPISIDTSTKVSRSVSINIPLVSSPMDTVTEDALAIALARLGGVG 92 Query: 85 IIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGK 144 +IH N T + N V VK + P + P + + + ++ PI Sbjct: 93 VIHRNMTINDEVNAVKAVKD-ASPYPVIPFSLNPLMSSEEAMAELRRLNLDTLPIVDE-- 149 Query: 145 LGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLP 204 GR+IG + + L+ K VM P+ G + + I+ ++ + Sbjct: 150 --GRVIGYIRRSRLLTGGRLIELAEKPVMAPV--------GSSGDELVKIMRENGTDTVA 199 Query: 205 IINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDV 264 +++ D + + + DL + A+ D +L+VGAA+ D +R + V+ D Sbjct: 200 LVDKDNVFIGIASYYDLNYKPPFKPAT-DGEGRLIVGAAVSPFDVER---AVKVSKYADF 255 Query: 265 IVLDSSQ-GNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDA--GVDALRVGMGS 321 +V+D + N + K +KET + V+ GN+ T A + I + RVG+ S Sbjct: 256 LVVDVAHVDNENALTALAKLVKET--PVDVIVGNLGTYDGAVDAITRVDPIGGFRVGIAS 313 Query: 322 GSICITQEVMACGCPQATAVYQVASYARHF---NVPVIADGGIQSVGHIIKSLALGASTV 378 GSIC T V P AV QVA A + + P+IADGGI+ G ++K++A GA Sbjct: 314 GSICSTGVVTGVAAPTLWAVAQVADAALDYGLGSTPIIADGGIREPGDVVKAMAAGAWAA 373 Query: 379 MMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHRVA 438 MMG + A +E+P K YRGM S E + AM RY K + + Sbjct: 374 MMGRVFAQATESPSPIIRVGNRLYKYYRGMAS----EGARARRFAMDRYAPKVKN---IE 426 Query: 439 QGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLE 498 +GV G + +G + + G+Q + +GA + + R RFM T S + E Sbjct: 427 EGVEGLVPYRGDLANIVREFVGGIQAALGYIGASNTAEARVKG-----RFMIVTESGRGE 481 Query: 499 GNVHGL 504 H L Sbjct: 482 VEPHDL 487 >UniRef50_Q6MM64 Cluster: Inosine-5-monophosphate dehydrogenase; n=1; Bdellovibrio bacteriovorus|Rep: Inosine-5-monophosphate dehydrogenase - Bdellovibrio bacteriovorus Length = 346 Score = 164 bits (399), Expect = 4e-39 Identities = 96/300 (32%), Positives = 168/300 (56%), Gaps = 23/300 (7%) Query: 206 INNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVI 265 +N G + L D+++ + K++ +++ G+ +G + + R K LV GV++I Sbjct: 67 MNQLGGMGILHRFLDIEEQAAQARRLKENGVKVISGS-VGVGEEFKTRAKALVEAGVNII 125 Query: 266 VLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSIC 325 +D + G+S ++ +K++K+ YP++ ++ GN+ T A++LI+AG DA++VG+G GS+C Sbjct: 126 TIDIAHGHSVQMMETMKWLKDQYPQVDLIAGNLATPDAARDLIEAGADAIKVGIGPGSMC 185 Query: 326 ITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLA 385 T+ + CG PQ TA+ A + VPVIADGGI++ G ++K+ A GASTVM+GS+L+ Sbjct: 186 TTRIITGCGVPQLTAIGLCAEIGESYGVPVIADGGIRTSGDMVKAFAAGASTVMLGSMLS 245 Query: 386 GTSEAPGEYFFSDGVRLKKYRGMGSLEAMES-KDGKGSAMSRYFHKESDKHRVAQGVSGS 444 GT E PGE +G K+YRGM S A +S + G M+ +G S Sbjct: 246 GTIETPGE--IKNG--KKQYRGMASRSAQDSWRGGVPEGMA------------PEGESTQ 289 Query: 445 IVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNVHGL 504 + KG V + + G++ + A S++ +++ + FM+ + + E HG+ Sbjct: 290 VTVKGHVKDVILEVTGGIRSGMSYINATSIAEIKDKA-----LFMEMSSNGIAESRAHGV 344 Score = 66.9 bits (156), Expect = 1e-09 Identities = 38/105 (36%), Positives = 58/105 (55%), Gaps = 1/105 (0%) Query: 16 EDTFANSEGLTYNDFLLLPGYIDFTAE-EVDLTSPLTKKILLKAPLVSTPMDTVTEADMA 74 +D +GLT++D L++P D + + LTS +TK ++ P+VS MD VTE DMA Sbjct: 5 KDIKNRGKGLTFDDVLIIPARSDVRSRRDPRLTSKVTKNFTIETPIVSANMDMVTEYDMA 64 Query: 75 ISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPE 119 +M GG+GI+H E QA + ++K+ I V +G E Sbjct: 65 FAMNQLGGMGILHRFLDIEEQAAQARRLKENGVKVISGSVGVGEE 109 >UniRef50_A1RZ33 Cluster: GMP reductase; n=1; Thermofilum pendens Hrk 5|Rep: GMP reductase - Thermofilum pendens (strain Hrk 5) Length = 349 Score = 151 bits (367), Expect = 3e-35 Identities = 103/273 (37%), Positives = 148/273 (54%), Gaps = 19/273 (6%) Query: 232 KDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEI 291 K S + L VG A+G D ER+ ++ G +IV+D++ G+S ++ + E Sbjct: 91 KISGENLPVGVAVGPFDD--ERVSKALDAGASIIVIDTAHGHSRNVLEATRRYAGMGAE- 147 Query: 292 QVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHF 351 V+ GN+VT A +LI AG +LRVG+G G C T+EV G PQ +AV +VA AR Sbjct: 148 -VMAGNIVTAEAALDLIGAGAVSLRVGVGPGHACTTREVAGVGYPQLSAVAKVADAARSH 206 Query: 352 NVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSL 411 V V+ADGGI+ I+K+LA GA VM+G LLAG+ EAPG G K YRGMGS Sbjct: 207 GVSVVADGGIEKPADIVKALAAGADAVMLGYLLAGSDEAPGHVVVRGGECFKVYRGMGSR 266 Query: 412 EAMESKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGA 471 A+ S GS +RY + RV +GV G + +G V + +L G++ +GA Sbjct: 267 GALRS----GS--TRY----GEFKRVPEGVEGLVPCRGPVEGVVEFLVNGLKQGMGYVGA 316 Query: 472 RSVSVLREMSHSGDLRFMKRTYSAQLEGNVHGL 504 R++ LR + F++ T++ E GL Sbjct: 317 RNLEELRVKA-----EFVRLTHAGVRESGPRGL 344 Score = 76.2 bits (179), Expect = 2e-12 Identities = 37/88 (42%), Positives = 57/88 (64%), Gaps = 1/88 (1%) Query: 16 EDTFANSE-GLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMA 74 E+ NSE GL+++D LL+P Y D +EVD+++ LTK +LLK P++S+PMDTVT +MA Sbjct: 5 EEKIKNSELGLSFDDVLLVPKYSDVRIDEVDVSTRLTKNLLLKIPIISSPMDTVTGFEMA 64 Query: 75 ISMALCGGIGIIHHNCTPEYQANEVHKV 102 + GG+G++ N + V K+ Sbjct: 65 RKLGELGGLGVLPRNIPLDAVVEYVKKI 92 >UniRef50_Q5V6J1 Cluster: Inosine-5'-monophosphate dehydrogenase; n=3; Halobacteriaceae|Rep: Inosine-5'-monophosphate dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 369 Score = 149 bits (360), Expect = 2e-34 Identities = 83/240 (34%), Positives = 127/240 (52%), Gaps = 11/240 (4%) Query: 240 VGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVV 299 VGAA+G + R ++ GVD +V+D + G+ + ++ + + +P+ ++ GNV Sbjct: 93 VGAAVGINEDYVARSAAVITAGVDALVVDVAHGHLNRALDAVETLADEFPDADIIAGNVA 152 Query: 300 TRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADG 359 T ++L AG D ++VG+G GS C T++V G PQ TAV A+ A +V + ADG Sbjct: 153 TPAGVEDLAAAGADCVKVGIGPGSHCTTRKVAGAGVPQLTAVDDCATAAEDLDVTICADG 212 Query: 360 GIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDG 419 GI++ G +K+L GA TVM+GSL AGT EAPG DG R K+ RGM + A E +D Sbjct: 213 GIRTSGDAVKALMAGADTVMLGSLFAGTEEAPGVVVEVDGTRYKRSRGMATTAAAEDRDD 272 Query: 420 KGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLRE 479 K + +S +GV KGSV AG++ G +++ R+ Sbjct: 273 KQNNVS-----------ADEGVEALTPYKGSVAAVAEEFCAGIRSGLSYCGGHTIAAARD 321 Score = 76.6 bits (180), Expect = 1e-12 Identities = 38/81 (46%), Positives = 54/81 (66%), Gaps = 3/81 (3%) Query: 24 GLTYNDFLLLP--GYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCG 81 GL+Y D LL+P +D + ++DL++PLT + L PLVS MDTVTEA++AI + G Sbjct: 7 GLSYGDVLLVPKRSPVD-SRSDIDLSTPLTPTVELDTPLVSAAMDTVTEAELAIELGQSG 65 Query: 82 GIGIIHHNCTPEYQANEVHKV 102 G G++H TPE QA +V +V Sbjct: 66 GFGVLHRFLTPEEQAEQVEQV 86 >UniRef50_Q1IAJ4 Cluster: Putative inosine-5'-monophosphate dehydrogenase; n=1; Pseudomonas entomophila L48|Rep: Putative inosine-5'-monophosphate dehydrogenase - Pseudomonas entomophila (strain L48) Length = 381 Score = 142 bits (344), Expect = 2e-32 Identities = 89/248 (35%), Positives = 127/248 (51%), Gaps = 5/248 (2%) Query: 233 DSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQ 292 DS +L VG +IG D +R L VD + LD + G+ST+ I I +KE +I Sbjct: 101 DSQGRLKVGGSIGIVDDYLQRAAGLAACDVDFLTLDIAHGHSTHAIAAIANVKERLGDIP 160 Query: 293 VVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFN 352 +V GNV T +L AG ++VG+G GS+C T+ V G PQ TA+ + A+ AR Sbjct: 161 IVAGNVATPEGVLDLAKAGASVIKVGIGPGSVCTTRSVTGAGVPQLTAILECAAAAREAG 220 Query: 353 VPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLE 412 V +IADGGI+S G I+K+LA GA VM+G +LAGT E+ + G R K RG + Sbjct: 221 VSIIADGGIRSSGDIVKALAAGAHAVMLGRMLAGTDESAAQLLEVSGKRFKLTRGFVTFG 280 Query: 413 A-MESKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGA 471 +E K +G ++ +E V +G+ G + +L L G+Q GA Sbjct: 281 TNLELKRLQGQKIT----EEQLLRYVPEGIEACFEYAGPLRAYLYQLIGGVQSGFSYCGA 336 Query: 472 RSVSVLRE 479 L E Sbjct: 337 SDYQQLLE 344 Score = 48.8 bits (111), Expect = 3e-04 Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Query: 23 EGLTYNDFLLLPGYIDFTA-EEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCG 81 +G ++D LL+P + ++ D+ L L P++S TE MA+ MA G Sbjct: 4 KGYVFDDVLLVPKKTHLASRKDADIGVELKGLGRLSVPVISANTQWCTEDRMAMEMARMG 63 Query: 82 GIGIIHHNCTPEYQANEVHKVK 103 G+GI+H C+ E Q VH VK Sbjct: 64 GLGIVHRMCSIEDQVAFVHAVK 85 >UniRef50_Q2JC64 Cluster: GMP reductase; n=2; Bacteria|Rep: GMP reductase - Frankia sp. (strain CcI3) Length = 385 Score = 140 bits (339), Expect = 8e-32 Identities = 83/254 (32%), Positives = 134/254 (52%), Gaps = 6/254 (2%) Query: 230 ASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYP 289 A+ D +LLVGAA+GT+ +R L+V +G D++++D + G+S I + + +P Sbjct: 100 ATVDPVGRLLVGAAVGTKGDYLDRAALMVEHGADLLLVDVAHGHSDQVIDTVGKLHARHP 159 Query: 290 EIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYAR 349 + +V GNV T +L+DAG D ++VG+G G +C T+ V G PQ TA+ A A Sbjct: 160 RVPIVAGNVATAGGTNDLLDAGADVVKVGIGPGGVCTTRLVAGSGVPQLTAIIDCAHAAA 219 Query: 350 HFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEA-PGEYFFSDGVRLKKYRGM 408 + VIADGG++ G + K+LA GA+ VM+GS LAG E+ G DG R + RG Sbjct: 220 QRDATVIADGGVRQSGDLAKALAAGAAAVMLGSALAGADESEAGVVDLPDGSRYRCSRGF 279 Query: 409 GSL-EAMESKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQ 467 +L A + G ++R + + +GV + G V + L G++ + Sbjct: 280 ATLGMANTLRAAAGGRLTR----DDVVGYIPEGVEMTFAPSGPVADTVYQLVGGLRSAMS 335 Query: 468 DLGARSVSVLREMS 481 GA ++ R ++ Sbjct: 336 YTGAADMAEFRRLA 349 Score = 45.2 bits (102), Expect = 0.004 Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Query: 24 GLTYNDFLLLPGYIDFTAE-EVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGG 82 GL+++D LL+P + +VD T L + L P++ T MA ++A GG Sbjct: 11 GLSFDDVLLVPHRTRVRSRADVDTTVDLAPGVRLWVPVIGANTQWCTGGAMAAALARVGG 70 Query: 83 IGIIHHNCTPEYQANEVHKVK 103 +G +H T E QA + VK Sbjct: 71 LGFVHRMQTVERQATHIASVK 91 >UniRef50_Q9P2T1 Cluster: GMP reductase 2; n=169; cellular organisms|Rep: GMP reductase 2 - Homo sapiens (Human) Length = 348 Score = 124 bits (299), Expect = 6e-27 Identities = 76/240 (31%), Positives = 128/240 (53%), Gaps = 13/240 (5%) Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297 + A+ GT +D E+L+ ++ V I LD + G S + ++ +K +++ +P+ ++ GN Sbjct: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158 Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357 VVT + LI +G D ++VG+G GS+C T++ G PQ +AV + A A +I+ Sbjct: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS 218 Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417 DGG G + K+ GA VM+G +LAG SE+ GE DG + K + GM S AM+ Sbjct: 219 DGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY 278 Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477 G G A ++R ++G + + KG V + + G++ +C +GA + L Sbjct: 279 AG-GVA----------EYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 327 >UniRef50_P60565 Cluster: GMP reductase; n=111; root|Rep: GMP reductase - Lactobacillus johnsonii Length = 330 Score = 121 bits (291), Expect = 5e-26 Identities = 70/180 (38%), Positives = 99/180 (55%), Gaps = 7/180 (3%) Query: 235 NKQLLVGAAIGTRDTDRERLKLLVNNGV--DVIVLDSSQGNSTYQIKMIKYIKETYPEIQ 292 +K L ++G +D++ + + L + + +D + G+S Y IKMIKYIKE P+ Sbjct: 88 DKGLFASISVGIKDSEYDFIDYLAKENIIPEYTTIDVAHGHSDYVIKMIKYIKEKLPDTF 147 Query: 293 VVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCP--QATAVYQVASYARH 350 + GN+ T + L +AG DA +VG+G G CIT+ G Q A+ + AR Sbjct: 148 LTAGNIATPEAVRELENAGADATKVGVGPGRACITKLKTGFGTGGWQLAALRMCSKAARK 207 Query: 351 FNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGS 410 P+IADGGI+ G I KS+ GAS VM+GSL AG E+PG DG R K+Y G S Sbjct: 208 ---PLIADGGIRHNGDIAKSVRFGASMVMIGSLFAGHEESPGNLITIDGKRYKQYWGSAS 264 >UniRef50_Q9YBU2 Cluster: Inosine-5'-monophosphate dehydrogenase; n=1; Aeropyrum pernix|Rep: Inosine-5'-monophosphate dehydrogenase - Aeropyrum pernix Length = 433 Score = 119 bits (287), Expect = 2e-25 Identities = 106/348 (30%), Positives = 169/348 (48%), Gaps = 34/348 (9%) Query: 150 IGIVTSRDIDFREGDPHLSLKEVMTPI--NDMITAQLGVTLQDANYILEKSKKGKLPIIN 207 +G++ R++ E H+S+ + ++P +++ +L L++ + ILE+ G + Sbjct: 72 VGVI-HRNMPREEQARHVSMVKSVSPSPWSEVPRIRLPDGLENYSLILEELDAGAAVVFG 130 Query: 208 NDG-ELVALIARTD----LKKARSY--------PNASKDSNKQLLVGAAIGTRDTDRERL 254 +DG + ++ R D L+KAR P + D +L+VGAA+ D DR RL Sbjct: 131 DDGIKGYLVLERPDAQLWLEKARYLSLYLTRIRPFPTIDGEGRLVVGAAVSPFDLDRARL 190 Query: 255 KLLVNNGVDVIVLDSSQGNSTYQIKMI-KYIKETYPEIQVVGGNVVTRMQAKNLIDAG-- 311 L +G D +V+D + ++ + + + +KE I VV GN+ TR + + Sbjct: 191 --LEKSGADFLVIDVAHLHNRNALSSLSRLVKEV--SIDVVAGNLGTREGVLDTLARAEE 246 Query: 312 VDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFN----VPVIADGGIQSVGHI 367 V LR+G+ SGSIC T EV P TAV +P+IADGG+++ G Sbjct: 247 VAGLRMGISSGSICSTGEVAGAAVPTLTAVMNAVLALEELGLAGRIPIIADGGVRNAGDA 306 Query: 368 IKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRY 427 K++ GAS VM G L AG E+PG K YRGM S AME + A+ RY Sbjct: 307 AKAIIAGASAVMGGRLFAGADESPGPRIRVGDKLYKPYRGMASRGAMERR----FAVDRY 362 Query: 428 FHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVS 475 + V +GV G + G V++ L L G++ + GA+ V+ Sbjct: 363 SRQAK---AVEEGVEGLVPYTGPVVKTLYELAEGLKAALGYAGAQDVT 407 Score = 73.3 bits (172), Expect = 1e-11 Identities = 35/79 (44%), Positives = 50/79 (63%) Query: 25 LTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGGIG 84 LT++D +LPG +V+L+S +++ I + PLVS+PMDTVTE MA ++A G +G Sbjct: 14 LTFDDVAILPGLSTVEPHDVELSSRVSRSIFVSTPLVSSPMDTVTEWRMAAALARLGAVG 73 Query: 85 IIHHNCTPEYQANEVHKVK 103 +IH N E QA V VK Sbjct: 74 VIHRNMPREEQARHVSMVK 92 >UniRef50_Q5ZRN7 Cluster: Inosine 5'-monophosphate dehydrogenase; n=4; Legionella pneumophila|Rep: Inosine 5'-monophosphate dehydrogenase - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 337 Score = 116 bits (279), Expect = 1e-24 Identities = 72/240 (30%), Positives = 123/240 (51%), Gaps = 16/240 (6%) Query: 240 VGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVV 299 V ++G + + +R + L + G D +D + ++ Y K +K +++ ++ GNV Sbjct: 89 VFVSVGCTENELQRAEALRDAGADFFCVDVAHAHAKYVGKTLKSLRQLLGSRCIMAGNVA 148 Query: 300 TRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADG 359 T A L G D ++ G+G GS+C T+ G P T + + R ++ADG Sbjct: 149 TYAGADYLASCGADIIKAGIGGGSVCSTRIKTGFGVPMLTCIQDCSRADR----SIVADG 204 Query: 360 GIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYF-FSDGVRLKKYRGMGSLEAMESKD 418 GI++ G I+K+LA GA VM+G +LAG++ PGE F DG ++K+YRGM S EA E+ Sbjct: 205 GIKTSGDIVKALAFGADFVMIGGMLAGSAPTPGEVFQKDDGSKVKRYRGMASREAQEA-- 262 Query: 419 GKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLR 478 F + + + A+GV+ + K + + + G++ GA S+S L+ Sbjct: 263 ---------FLGQMHEWKTAEGVATEVPFKENPDGIIADIIGGLRSGLTYAGADSISELQ 313 Score = 50.4 bits (115), Expect = 1e-04 Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 2/83 (2%) Query: 23 EGLTYNDFLLLPGYIDFTAEEVDLTSPLTK--KILLKAPLVSTPMDTVTEADMAISMALC 80 + +T++D LL+P Y + V T+ + K+ L P++S MDT+TE++MA M Sbjct: 4 QAITFDDVLLVPSYNHHESRRVVETTSTDRLGKLTLNLPVISANMDTITESNMANFMHSK 63 Query: 81 GGIGIIHHNCTPEYQANEVHKVK 103 G +G +H T E E K K Sbjct: 64 GAMGALHRFMTIEENIQEFKKCK 86 >UniRef50_A4GHK1 Cluster: Guanosine monophosphate reductase; n=1; uncultured marine bacterium EB0_35D03|Rep: Guanosine monophosphate reductase - uncultured marine bacterium EB0_35D03 Length = 366 Score = 105 bits (251), Expect = 4e-21 Identities = 76/281 (27%), Positives = 134/281 (47%), Gaps = 14/281 (4%) Query: 205 IINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLL---VNNG 261 I++ L+ + + +Y NA D ++ V +IG D D + K + V+ G Sbjct: 72 ILSKQQIFTCLVKTLAVDELVNYFNAKNDFRREH-VAMSIGITDNDSAKFKEVYKQVDKG 130 Query: 262 -VDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMG 320 + + +D + G S ++ ++ YP + ++ GNVVT + LI G D ++VG+G Sbjct: 131 NLKYVCIDVANGYSERFSNFVRKFRKQYPNVVIIAGNVVTGEMTEELILNGADIVKVGIG 190 Query: 321 SGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMM 380 GS+C T+ G PQ +AV + A A +IADGG S G ++K+ A G+ VM+ Sbjct: 191 PGSVCTTRIQTGVGYPQLSAVIECADAAHGLGGHIIADGGCASPGDVVKAFAGGSDFVML 250 Query: 381 GSLLAGTSEAPGEY----FFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHR 436 G +LAG E G+ + + V + + + M S +A ++F D +R Sbjct: 251 GGMLAGHDEGGGKIITKEYITKEVDVTEEKSFIQFYGMSS----DAANVKHFGGLKD-YR 305 Query: 437 VAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477 ++G + +G V + + G++ SC GA+ + L Sbjct: 306 SSEGREVLVPYRGEVSNTIQDILGGIRSSCTYAGAQRLKHL 346 >UniRef50_Q7NTY1 Cluster: GMP reductase; n=1; Chromobacterium violaceum|Rep: GMP reductase - Chromobacterium violaceum Length = 316 Score = 101 bits (243), Expect = 3e-20 Identities = 78/245 (31%), Positives = 116/245 (47%), Gaps = 23/245 (9%) Query: 238 LLVGAAIGTRDTDRERLKLLVNNGV--DVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVG 295 L ++G D E+L L G+ + + LD + +MIK+IK+ +P ++G Sbjct: 86 LFASISVGVNDDTYEQLDALKAAGLSPEYMTLDIANAWCVKAERMIKHIKQHFPNTFLIG 145 Query: 296 GNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPV 355 GNV T A++L G DA++ G+ G +CIT+ P + V + +PV Sbjct: 146 GNVATAEAARDLEAWGCDAIKAGIAGGRVCITKNKTGFHRPMVSTVRDCVAAV---TIPV 202 Query: 356 IADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAME 415 IADGGI G I K+L GA+ VM GSL AG E+ G+ G K+Y G Sbjct: 203 IADGGIVEHGDIAKALVCGATMVMAGSLFAGYDESAGDIVEIAGKHYKEYFGSA------ 256 Query: 416 SKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVS 475 S+ KG+ Y + E K V KGS+ + L LQ +Q S G +++ Sbjct: 257 SQFNKGA----YVNVEGKKILVEY--------KGSMGKLLRELQEDLQSSVSYAGGTTLA 304 Query: 476 VLREM 480 LRE+ Sbjct: 305 ALREV 309 >UniRef50_Q4S0S1 Cluster: Chromosome undetermined SCAF14779, whole genome shotgun sequence; n=8; Eumetazoa|Rep: Chromosome undetermined SCAF14779, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 271 Score = 98.7 bits (235), Expect = 3e-19 Identities = 64/190 (33%), Positives = 96/190 (50%), Gaps = 5/190 (2%) Query: 288 YPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASY 347 +PE V GNVVT + LI AG D ++VG+G GS+C T++ G PQ +AV + A Sbjct: 70 HPEC-VKAGNVVTGEMVEELILAGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVIECADA 128 Query: 348 ARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRG 407 A +I+DGG G + K+ GA VM+G +LAG SE+ G+ G + K + G Sbjct: 129 AHGLGGHIISDGGCTCPGDVSKAFGAGADFVMLGGMLAGHSESGGDIIEKSGKKYKLFYG 188 Query: 408 MGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQ 467 M S AM G G A + S ++G + + KG V + + G++ +C Sbjct: 189 MSSDTAMRKHAG-GVA---EYRSASASCGASEGKTVEVPYKGPVEVTIRDVLGGVRSTCT 244 Query: 468 DLGARSVSVL 477 +GA + L Sbjct: 245 YVGAGKLKEL 254 >UniRef50_Q4X988 Cluster: Putative uncharacterized protein; n=6; Plasmodium|Rep: Putative uncharacterized protein - Plasmodium chabaudi Length = 187 Score = 97.5 bits (232), Expect = 7e-19 Identities = 46/97 (47%), Positives = 69/97 (71%), Gaps = 1/97 (1%) Query: 186 VTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIG 245 ++L DAN +L KK LPI+N++ EL+AL+ R D+ K + +P+ASK NKQL+VGA+I Sbjct: 2 ISLSDANKVLCDEKK-ILPIVNDNYELIALVCRNDMHKNKIFPHASKRENKQLIVGASIS 60 Query: 246 TRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIK 282 TR++D E++ L N +D+I +DSSQGNS + +K Sbjct: 61 TRESDLEKVNKLAQNMIDIICIDSSQGNSVTSLSFMK 97 >UniRef50_Q4S0S8 Cluster: Chromosome undetermined SCAF14779, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14779, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 376 Score = 97.1 bits (231), Expect = 1e-18 Identities = 61/182 (33%), Positives = 92/182 (50%), Gaps = 4/182 (2%) Query: 296 GNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPV 355 GNVVT + LI AG D ++VG+G GS+C T++ G PQ +AV + A A + Sbjct: 178 GNVVTGEMVEELILAGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVIECADAAHGLGGHI 237 Query: 356 IADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAME 415 I+DGG G + K+ GA VM+G +LAG SE+ G+ G + K + GM S AM Sbjct: 238 ISDGGCTCPGDVSKAFGAGADFVMLGGMLAGHSESGGDIIEKSGKKYKLFYGMSSDTAMR 297 Query: 416 SKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVS 475 G G A + S ++G + + KG V + + G++ +C +GA + Sbjct: 298 KHAG-GVA---EYRSASASCGASEGKTVEVPYKGPVEVTIRDVLGGVRSTCTYVGAGKLK 353 Query: 476 VL 477 L Sbjct: 354 EL 355 >UniRef50_Q0PQW0 Cluster: Putative inosine-5'-monophosphate dehydrogenase; n=1; Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Putative inosine-5'-monophosphate dehydrogenase - Endoriftia persephone 'Hot96_1+Hot96_2' Length = 173 Score = 95.1 bits (226), Expect = 4e-18 Identities = 46/86 (53%), Positives = 58/86 (67%) Query: 308 IDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHI 367 +DAG DA++VG+G GSIC T+ V G PQ TAV VA VP+IADGG++ G I Sbjct: 1 VDAGADAVKVGIGPGSICTTRIVAGVGVPQVTAVSNVAKQLEDSGVPLIADGGLRYSGDI 60 Query: 368 IKSLALGASTVMMGSLLAGTSEAPGE 393 K LA GA +VM+G + AGT E+PGE Sbjct: 61 AKVLASGAYSVMVGGMFAGTDESPGE 86 >UniRef50_Q4UGU3 Cluster: Gmp reductase, putative; n=3; Piroplasmida|Rep: Gmp reductase, putative - Theileria annulata Length = 330 Score = 92.7 bits (220), Expect = 2e-17 Identities = 61/181 (33%), Positives = 94/181 (51%), Gaps = 7/181 (3%) Query: 238 LLVGAAIGTRDTDRERL-KLLVNNGV-DVIVLDSSQGNSTYQIKMIKYIKETYP-EIQVV 294 L V ++G ++ + + +L NN V D I +D S G++ MI +I+ + + ++ Sbjct: 95 LFVSISVGVKEESYDVVTELKENNEVPDFITIDISHGHNQRVKGMIDHIRSCFGNKTFII 154 Query: 295 GGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCP--QATAVYQVASYARHFN 352 GNV T +++ G +A++VG+G G C T G Q +AV + A A Sbjct: 155 AGNVTTPEGIRDMESWGANAIKVGLGPGHACTTSPRTGFGSRGWQLSAVARCAKVAT--K 212 Query: 353 VPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLE 412 +I DGG + G I K++ +GA +M G L +GT E+PGE DGVR K Y G SL Sbjct: 213 AVIICDGGASNSGDIAKAINMGADWIMSGFLFSGTLESPGEIVVRDGVRCKSYYGSSSLV 272 Query: 413 A 413 A Sbjct: 273 A 273 >UniRef50_Q2JL45 Cluster: IMP dehydrogenase family protein; n=43; Bacteria|Rep: IMP dehydrogenase family protein - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 387 Score = 84.2 bits (199), Expect = 7e-15 Identities = 50/111 (45%), Positives = 64/111 (57%), Gaps = 6/111 (5%) Query: 291 IQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARH 350 I VV GN VT A L+ AG + VG+G G+ C ++ V+ G PQATA+ A+ Sbjct: 188 IPVVVGNCVTYDVALELMQAGAAGVLVGIGPGAACTSRGVLGVGVPQATAIADCAAAREQ 247 Query: 351 F------NVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYF 395 F VPVIADGG+ + G I K++A GA VM+GS LA EAPG F Sbjct: 248 FLAETGAYVPVIADGGLVTGGDICKAIACGADAVMIGSPLARAYEAPGRGF 298 >UniRef50_Q5RGU9 Cluster: Novel protein similar to vertebrate IMP (Inosine monophosphate) dehydrogenase 1; n=1; Danio rerio|Rep: Novel protein similar to vertebrate IMP (Inosine monophosphate) dehydrogenase 1 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 126 Score = 77.4 bits (182), Expect = 8e-13 Identities = 35/47 (74%), Positives = 41/47 (87%) Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLK 57 DGLSA+ FA +GLTYNDFL+LPG+IDFT++EVDLTS LTKKI LK Sbjct: 80 DGLSAQQLFAVGDGLTYNDFLILPGFIDFTSDEVDLTSALTKKITLK 126 >UniRef50_Q7VQ71 Cluster: GuaB gene for inosine 5-monophosphase dehydrogenase subunit; n=4; cellular organisms|Rep: GuaB gene for inosine 5-monophosphase dehydrogenase subunit - Chlamydia pneumoniae (Chlamydophila pneumoniae) Length = 87 Score = 73.7 bits (173), Expect = 1e-11 Identities = 33/82 (40%), Positives = 54/82 (65%) Query: 23 EGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGG 82 E LT++D LL+P Y + EV L + ++K + L P++S MD+VTE MA+++A GG Sbjct: 3 EALTFDDVLLIPQYSEILPSEVSLKTAISKTLSLNIPILSAAMDSVTETAMALALAQEGG 62 Query: 83 IGIIHHNCTPEYQANEVHKVKK 104 +GI+H N + Q++ V K+K+ Sbjct: 63 LGILHKNMSEVEQSSSVRKIKE 84 >UniRef50_Q4T162 Cluster: Chromosome 21 SCAF10714, whole genome shotgun sequence; n=2; cellular organisms|Rep: Chromosome 21 SCAF10714, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 364 Score = 70.9 bits (166), Expect = 7e-11 Identities = 38/120 (31%), Positives = 66/120 (55%), Gaps = 2/120 (1%) Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297 V A+ G+ D E+L ++ + I LD + G S + ++ +K ++E +P+ ++ GN Sbjct: 104 VAASSGSSAADLEKLCSVLEAVPALQYICLDVANGYSEHFVEFVKMVREKFPKHTIMAGN 163 Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357 VVT + LI +G D ++VG+G GS+C T+ G PQ +AV + A A +I+ Sbjct: 164 VVTGEMVEELILSGADIIKVGIGPGSVCTTRIKTGVGYPQLSAVIECADSAHGLKGHIIS 223 >UniRef50_Q8EUA0 Cluster: Guanosine 5'-monophosphate oxidoreductase; n=1; Mycoplasma penetrans|Rep: Guanosine 5'-monophosphate oxidoreductase - Mycoplasma penetrans Length = 378 Score = 70.9 bits (166), Expect = 7e-11 Identities = 43/146 (29%), Positives = 73/146 (50%), Gaps = 12/146 (8%) Query: 265 IVLDSSQGNSTYQIKMIKYIKETYP-EIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGS 323 I++D S G+ I+ +K + +I ++ GN+ + + L +AG D +RVG+G+G Sbjct: 112 ILIDISNGHMRRLANSIRDLKRIFRNKISIMCGNIANPLTFQYLSEAGADYIRVGIGAGC 171 Query: 324 ICITQEVMACGCPQATAVYQVASYARHFN-----------VPVIADGGIQSVGHIIKSLA 372 CIT P + +Y+ ++ADGG+++ +IIKSL Sbjct: 172 GCITASNTGIFYPMGSLIYECRKIQEKMEESYRLNGTSKPAKIVADGGMKNYDYIIKSLY 231 Query: 373 LGASTVMMGSLLAGTSEAPGEYFFSD 398 LGA VM G L + E+PGE ++ + Sbjct: 232 LGADYVMCGRLFSQCWESPGEIWYKE 257 >UniRef50_A1SMV5 Cluster: IMP dehydrogenase family protein; n=7; Actinobacteridae|Rep: IMP dehydrogenase family protein - Nocardioides sp. (strain BAA-499 / JS614) Length = 368 Score = 69.7 bits (163), Expect = 2e-10 Identities = 49/152 (32%), Positives = 77/152 (50%), Gaps = 11/152 (7%) Query: 255 KLLVNNGVDVIVLDSSQGNSTY---QIKMIKYIKETYP-EIQVVGGNVVTRMQAKNLIDA 310 K +V+ GVD+ V+ + ++ + Q + + + Y ++ VV G T A +L+ Sbjct: 148 KAVVDAGVDMFVIRGTTVSAEHVSSQAEPLNLKEFIYELDVPVVVGGCATHQAALHLMRT 207 Query: 311 GVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHF-------NVPVIADGGIQS 363 G + VG G G+ T+ V+ P A+AV VA+ R + V VIADG I Sbjct: 208 GAAGVLVGFGGGAAHTTRTVLGVAVPMASAVADVAAARRDYLDESGGRYVHVIADGSIGK 267 Query: 364 VGHIIKSLALGASTVMMGSLLAGTSEAPGEYF 395 G + K++A GA VM+GS A ++APG F Sbjct: 268 SGDVAKAIACGADAVMVGSPFARATDAPGRGF 299 >UniRef50_Q03YG3 Cluster: IMP dehydrogenase/GMP reductase; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: IMP dehydrogenase/GMP reductase - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 328 Score = 68.9 bits (161), Expect = 3e-10 Identities = 52/170 (30%), Positives = 78/170 (45%), Gaps = 6/170 (3%) Query: 227 YPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKE 286 YPNA DS L V A + R+ LVN G D I + + +IK I++ Sbjct: 96 YPNALVDSQNHLRVAAEVWLVAGAETRVAALVNAGADAIFFYLHETLAKNTRDLIKQIRQ 155 Query: 287 TYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVAS 346 +P++ + G V + A L +AG D + G S + ++ P T +A Sbjct: 156 AHPDLFIAVGVVEDQSIAAALYEAGADTILAGRSVDS-SLPNDITY---PFLTVTMNIAD 211 Query: 347 YARHF-NVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGT-SEAPGEY 394 A + N VIA GGI G I+K++A GA M+ LL G+ E+ G + Sbjct: 212 VAAAYDNKSVIAVGGIHYSGDIVKAIAAGADATMVSDLLKGSVLESDGSF 261 Score = 38.3 bits (85), Expect = 0.48 Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Query: 24 GLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGGI 83 GL Y+ LL+PG + V L + L++ L PLVS T+ +A AL GG+ Sbjct: 9 GLGYDQVLLVPGASNVLPYSVTLRTQLSENFELNIPLVSEAFGPETDTRVA-PTALNGGL 67 Query: 84 GIIHHNCTPEYQANEVHKVKK 104 G++ Q + +VK+ Sbjct: 68 GVVAEQEDLSKQVASLQQVKE 88 >UniRef50_P74477 Cluster: Chloride channel protein; n=3; Chroococcales|Rep: Chloride channel protein - Synechocystis sp. (strain PCC 6803) Length = 899 Score = 65.7 bits (153), Expect = 3e-09 Identities = 34/102 (33%), Positives = 58/102 (56%), Gaps = 7/102 (6%) Query: 121 TVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI-DFREGDPHLSLKEVMTPINDM 179 T+A VL + G+P+ Q GG+L+G+ T D+ + + H++LK++MTP + Sbjct: 471 TLAQVLPIMSNSHHRGFPVVQ----GGKLVGVFTQTDLANAAQESVHIALKQIMTP--NP 524 Query: 180 ITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 IT L D Y+L + + +LP++ D +LV +I RTD+ Sbjct: 525 ITVDPEAPLSDVLYLLNRYQLSRLPVVEGDNKLVGIITRTDI 566 >UniRef50_A6Y440 Cluster: GMP reductase; n=1; Vibrio cholerae RC385|Rep: GMP reductase - Vibrio cholerae RC385 Length = 248 Score = 64.5 bits (150), Expect = 6e-09 Identities = 34/122 (27%), Positives = 68/122 (55%), Gaps = 4/122 (3%) Query: 232 KDSNKQLL--VGAAIGTRDTDRERLK--LLVNNGVDVIVLDSSQGNSTYQIKMIKYIKET 287 K ++K L V + GT + D ++ K + +++ + I +D + G S + ++ ++ ++ Sbjct: 89 KSADKATLNNVMVSTGTSEADFQKTKDVMALSDELIFICIDIANGYSEHLVEYVQRVRAA 148 Query: 288 YPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASY 347 +P+ + GNVVT + LI AG D ++VG+G GS+C T+ G PQ +A+ + + Sbjct: 149 FPDKVISAGNVVTGDMVEELILAGADIVKVGIGPGSVCTTRVKTGVGYPQLSAIIEYTAQ 208 Query: 348 AR 349 + Sbjct: 209 TK 210 >UniRef50_P65170 Cluster: Uncharacterized oxidoreductase Rv3410c/MT3518; n=31; Actinomycetales|Rep: Uncharacterized oxidoreductase Rv3410c/MT3518 - Mycobacterium tuberculosis Length = 375 Score = 64.5 bits (150), Expect = 6e-09 Identities = 48/155 (30%), Positives = 79/155 (50%), Gaps = 16/155 (10%) Query: 256 LLVNNGVDVIVLDSS------QGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309 +LV G+D++V+ + + + + +I E +I VV G V+ A +L+ Sbjct: 152 VLVAAGIDLLVIQGTIVSAERVASDGEPLNLKTFISEL--DIPVVAGGVLDHRTALHLMR 209 Query: 310 AGVDALRVGMGSGS-ICITQEVMACGCPQATAVYQVASYARHF-------NVPVIADGGI 361 G + VG GS + T EV+ P ATA+ A+ R + V V+ADG I Sbjct: 210 TGAAGVIVGYGSTQGVTTTDEVLGISVPMATAIADAAAARRDYLDETGGRYVHVLADGDI 269 Query: 362 QSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFF 396 + G + K++A GA V++G+ LA ++EA GE +F Sbjct: 270 HTSGELAKAIACGADAVVLGTPLAESAEALGEGWF 304 >UniRef50_Q57647 Cluster: Uncharacterized protein MJ0188; n=6; Methanococcales|Rep: Uncharacterized protein MJ0188 - Methanococcus jannaschii Length = 265 Score = 63.3 bits (147), Expect = 1e-08 Identities = 34/112 (30%), Positives = 62/112 (55%), Gaps = 6/112 (5%) Query: 114 VCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVM 173 V + +NTV DV++ K+ G +P+ +NGK LIGIV+ DI + D + ++ VM Sbjct: 14 VTVSKDNTVKDVIKLLKETGHNSFPVVENGK----LIGIVSVHDIVGK--DDNEKVENVM 67 Query: 174 TPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKAR 225 T DM+ + D I+ ++ KLP+++ + LV +I+ D+ +++ Sbjct: 68 TKRKDMVVTTPDANIMDVGRIMFRTGFSKLPVVDEENNLVGIISNMDVIRSQ 119 >UniRef50_Q0S3A9 Cluster: Possible IMP dehydrogenase/GMP reductase; n=17; Actinobacteria (class)|Rep: Possible IMP dehydrogenase/GMP reductase - Rhodococcus sp. (strain RHA1) Length = 379 Score = 62.9 bits (146), Expect = 2e-08 Identities = 49/147 (33%), Positives = 72/147 (48%), Gaps = 11/147 (7%) Query: 254 LKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVD 313 + LLV +G + G+S + + +I E ++ VV G V A +L+ G Sbjct: 161 IDLLVVHGTIISAEHVVHGDSE-PLNLKTFISEL--DVPVVAGGVSDHRTALHLMRTGAA 217 Query: 314 ALRVGMGSGS-ICITQEVMACGCPQATAVYQVASYARHF-------NVPVIADGGIQSVG 365 + VG GS T EV+ G P ATA+ A+ R + V VIADG I S G Sbjct: 218 GVIVGYGSTEGATTTGEVLGIGLPMATAIADAAAARRDYLDETGGRYVHVIADGDITSSG 277 Query: 366 HIIKSLALGASTVMMGSLLAGTSEAPG 392 + K++A GA ++G+ LA +EAPG Sbjct: 278 DLAKAIACGADAAVLGAPLAVAAEAPG 304 >UniRef50_O27343 Cluster: Inosine-5'-monophosphate dehydrogenase related protein VI; n=3; Methanobacteriaceae|Rep: Inosine-5'-monophosphate dehydrogenase related protein VI - Methanobacterium thermoautotrophicum Length = 269 Score = 62.1 bits (144), Expect = 3e-08 Identities = 50/176 (28%), Positives = 91/176 (51%), Gaps = 20/176 (11%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK 170 RD + + + + A++++ K+ G G+P+ NG + IG+VT+ D+ + +S Sbjct: 13 RDVITVSSDTSTAEIIKLMKETGHDGFPVKDNGSV----IGMVTAFDLLIKPWVKTVS-- 66 Query: 171 EVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA---RSY 227 E+M+ D++ A ++L DA ++ + +LP+IN +G+LV +I TD+ ++ RS Sbjct: 67 EIMS--RDVVVADQDMSLNDAARVMFRMGISRLPVINKEGKLVGIITNTDIVRSHIERST 124 Query: 228 P---NASKDSNKQLL-VGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIK 279 P N K + +QL V + E+L+ N + D QG TY+IK Sbjct: 125 PMKVNYFKKTLEQLYGVKPEVKRMKVPIEKLRPTQNK----VYADELQGR-TYEIK 175 >UniRef50_O29009 Cluster: Inosine monophosphate dehydrogenase, putative; n=4; Euryarchaeota|Rep: Inosine monophosphate dehydrogenase, putative - Archaeoglobus fulgidus Length = 259 Score = 57.2 bits (132), Expect = 1e-06 Identities = 28/122 (22%), Positives = 67/122 (54%), Gaps = 7/122 (5%) Query: 104 KYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREG 163 K K ++ + P+NTV D +E +K G +P+ + R++G +++ +D + Sbjct: 4 KVKDYMTKNVYTLKPDNTVKDAIELVRKTGHDSFPVVDDNM---RVVGYISA--VDLLDK 58 Query: 164 DPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 P ++++M+ ++ A+ + L+DA ++ ++ KLP+++ D LV +I+ D+ + Sbjct: 59 SPETKIRDIMS--RELYVARDFMDLRDAARVMFRTGHSKLPVVDEDNRLVGIISNADVIR 116 Query: 224 AR 225 ++ Sbjct: 117 SQ 118 >UniRef50_O28857 Cluster: Chloride channel, putative; n=2; Euryarchaeota|Rep: Chloride channel, putative - Archaeoglobus fulgidus Length = 589 Score = 56.0 bits (129), Expect = 2e-06 Identities = 37/118 (31%), Positives = 67/118 (56%), Gaps = 12/118 (10%) Query: 114 VCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID---FREGDPHLSLK 170 V + P V++VLE +K G G+P+ + GRL+G+VT D++ E D L ++ Sbjct: 471 VVVTPYQRVSEVLELIEKTGHMGFPVV----MDGRLVGMVTFEDVERVPLEERDKKL-VR 525 Query: 171 EVMTPINDMITAQLGVTLQDANYILEKSKKGKLPII--NNDGELVALIARTDLKKARS 226 ++MT ++I TL++A L G+LP++ N++ +L+ +I R+D+ KA + Sbjct: 526 DIMT--RELIVTYPDETLEEALIKLVDKGIGRLPVVDRNDEKKLLGIITRSDIMKAHA 581 >UniRef50_Q191T3 Cluster: Polynucleotide adenylyltransferase region precursor; n=3; Bacteria|Rep: Polynucleotide adenylyltransferase region precursor - Desulfitobacterium hafniense (strain DCB-2) Length = 873 Score = 55.6 bits (128), Expect = 3e-06 Identities = 31/128 (24%), Positives = 67/128 (52%), Gaps = 9/128 (7%) Query: 96 ANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTS 155 A + H++ + + + PE +++V + K G TG P+ Q G +L+GI++ Sbjct: 298 AQQAHRINRVRDIMSYPVKTVSPEMKLSEVEQILLKYGHTGVPVAQ----GEKLVGIISR 353 Query: 156 RDID--FREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELV 213 RD+D + G H +K MT D++ + + +D + + G++P++ +G+L Sbjct: 354 RDVDKAIKHGLAHAPVKGFMT--KDVVVVEADSSWEDVQRTMVQHDIGRVPVL-EEGKLA 410 Query: 214 ALIARTDL 221 +++R+D+ Sbjct: 411 GIVSRSDI 418 >UniRef50_O26907 Cluster: Sporulation protein IVFB related protein; n=1; Methanothermobacter thermautotrophicus str. Delta H|Rep: Sporulation protein IVFB related protein - Methanobacterium thermoautotrophicum Length = 341 Score = 55.6 bits (128), Expect = 3e-06 Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 9/118 (7%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKE 171 +PV + P TV + L+ + GYP+T+ G L GIVT DI D L +++ Sbjct: 229 NPVTLHPHMTVKEALDVMFREKHMGYPVTE----AGELRGIVTFHDISDASRD--LRVED 282 Query: 172 VMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPN 229 VMT D++T + + A + + + G+LP++ DG+L +I+RTD+ + + N Sbjct: 283 VMT--GDVVTVRDDEEVTGALEKMNRLQLGRLPVM-RDGKLTGIISRTDIVRTLNLMN 337 >UniRef50_Q2NEF3 Cluster: Putative uncharacterized protein; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Putative uncharacterized protein - Methanosphaera stadtmanae (strain DSM 3091) Length = 311 Score = 54.4 bits (125), Expect = 7e-06 Identities = 55/225 (24%), Positives = 103/225 (45%), Gaps = 24/225 (10%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI-DFREG------ 163 +D V +++ ++ KN F PIT G G+L+GIVT+ DI DF G Sbjct: 34 KDVVTAPQSSSIIEIANLMSKNDFRRIPITDPGS--GKLLGIVTTMDILDFFGGGKKYNI 91 Query: 164 --DPHLS--LKEVMTPINDMITAQLGV-----TLQDANYILEKSKKGKLPIINNDGELVA 214 D H L + PI +++T + T+ D ++ + G LPIINND ++V Sbjct: 92 ITDKHKGNFLSAINAPIKEIMTVGVKTMTNTDTIVDTTTLMLEEGIGGLPIINNDEKIVG 151 Query: 215 LIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERL-KLLVNNGV-DVIVLDSSQG 272 ++ D+ K A + + T T E + K++V N + V ++ Q Sbjct: 152 IVTEGDIVKKLGKLCADLEVQDIMATNVITTTPGTPIEGIAKIMVRNSLRRVPIVGEDQE 211 Query: 273 NSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRV 317 + + + K++ ++ + ++ +G + ++ AK + G D ++V Sbjct: 212 SQSKEEKLLGFVTAS-DILKYIGDH---KLFAKLFSNEGEDVVKV 252 >UniRef50_Q97F91 Cluster: Proline/glycine betaine ABC-type transport system, ATPase component; n=42; Bacteria|Rep: Proline/glycine betaine ABC-type transport system, ATPase component - Clostridium acetobutylicum Length = 377 Score = 53.6 bits (123), Expect = 1e-05 Identities = 39/132 (29%), Positives = 62/132 (46%), Gaps = 6/132 (4%) Query: 104 KYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREG 163 K K I + + PE T LE K N + +L+GIVT R++ F Sbjct: 249 KVKDIMINNVIKSSPERTSIQALEIMKSNHVDRLIVASKDN---KLLGIVTLRELKFSIN 305 Query: 164 DPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 + + LK++M N++ T ++ + I+E K G +P+INND LV LI ++ L Sbjct: 306 E-NKKLKDIMK--NNITTINENDSIVNVLDIVENQKIGFIPVINNDSSLVGLITKSSLLS 362 Query: 224 ARSYPNASKDSN 235 S +K+ N Sbjct: 363 VLSNQFINKEVN 374 >UniRef50_Q02B15 Cluster: Putative signal-transduction protein with CBS domains; n=1; Solibacter usitatus Ellin6076|Rep: Putative signal-transduction protein with CBS domains - Solibacter usitatus (strain Ellin6076) Length = 147 Score = 53.6 bits (123), Expect = 1e-05 Identities = 38/130 (29%), Positives = 67/130 (51%), Gaps = 8/130 (6%) Query: 104 KYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR-- 161 K K DPVC P +TV++V + K P+ ++ + +L+GI+T RD+ + Sbjct: 2 KCKQAMTPDPVCCIPTDTVSNVAKRMKTEDVGSLPVCES-RTSRKLVGIITDRDLAIKVV 60 Query: 162 --EGDPH-LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIAR 218 DP+ ++ +VMT N M T L A + ++ + ++PI+N+ G LV +I++ Sbjct: 61 ADSRDPNKVTTGDVMT-WNPM-TCHPDDDLDIAVHSMQSEQVRRIPIVNDAGVLVGIISQ 118 Query: 219 TDLKKARSYP 228 D+ S P Sbjct: 119 ADIALRGSRP 128 >UniRef50_Q64C69 Cluster: Chloride channel; n=1; uncultured archaeon GZfos26B2|Rep: Chloride channel - uncultured archaeon GZfos26B2 Length = 608 Score = 53.6 bits (123), Expect = 1e-05 Identities = 33/114 (28%), Positives = 61/114 (53%), Gaps = 8/114 (7%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID-FREGD-PHLSL 169 D + + P N V VL K G GYP+ + RL+G+VT +D + + GD + + Sbjct: 491 DVMPVNPTNNVQTVLNLITKYGHIGYPVLDDN----RLVGVVTFKDAERVQAGDREEVLV 546 Query: 170 KEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINND--GELVALIARTDL 221 +VMTP +I +L+DA L + G+LP+++ D +++ ++ ++D+ Sbjct: 547 DQVMTPATSLIVTYPDESLEDALRKLVLNDIGRLPVVDRDDQSKILGIVTKSDI 600 >UniRef50_O27290 Cluster: Inosine-5'-monophosphate dehydrogenase related protein I; n=1; Methanothermobacter thermautotrophicus str. Delta H|Rep: Inosine-5'-monophosphate dehydrogenase related protein I - Methanobacterium thermoautotrophicum Length = 275 Score = 53.2 bits (122), Expect = 2e-05 Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 12/119 (10%) Query: 112 DPVCMGPENTVADVLE-AKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGD------ 164 DPVC+ + + D L K+N I N L+GIVT +DI + G Sbjct: 13 DPVCIDKDQNICDALRLMDKRNVSRLLVINTNSDHERELVGIVTEKDIALKLGSSRYGNM 72 Query: 165 --PHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 H + VMTP ++ITA+ + +A ++ ++ G LP++ +DGE++ ++ ++DL Sbjct: 73 APSHFHVSTVMTP--ELITAEPDMDAGNAASVMLENNIGSLPVL-HDGEIMGIVTKSDL 128 >UniRef50_Q4TGB6 Cluster: Chromosome undetermined SCAF3807, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF3807, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 258 Score = 52.8 bits (121), Expect = 2e-05 Identities = 45/189 (23%), Positives = 84/189 (44%), Gaps = 8/189 (4%) Query: 241 GAAIGTRDTDRERLKLLVNNGVDV--IVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNV 298 G + GT +TD ER+ ++ ++ I +D + G S + + +K ++E +P ++ G + Sbjct: 2 GFSTGTGETDFERISAILAAVPELQYICVDVANGYSEHFVHFVKDVREKFPSHTIMVGPL 61 Query: 299 VTRMQAKNLIDAGVDALRVG-MGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357 R + L+ + + G + +G + +E++ G S Sbjct: 62 PPRPRQPALLHRRISVCQAGNVVTGEM--VEELILAGADIIKVGIGPGSVCT--TRKKTG 117 Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKY-RGMGSLEAMES 416 DGG G + K+ GA VM+G +LAG SE+ G+ G + K + R E+ Sbjct: 118 DGGCTCPGDVSKAFGAGADFVMLGGMLAGHSESGGDIIEKSGKKYKLFLRNELRHGHEEA 177 Query: 417 KDGKGSAMS 425 + G+G S Sbjct: 178 RGGRGRVQS 186 >UniRef50_Q9HRK9 Cluster: Inosine-5'-monophosphate dehydrogenase; n=5; Euryarchaeota|Rep: Inosine-5'-monophosphate dehydrogenase - Halobacterium salinarium (Halobacterium halobium) Length = 272 Score = 52.0 bits (119), Expect = 4e-05 Identities = 33/115 (28%), Positives = 62/115 (53%), Gaps = 8/115 (6%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK 170 RD + ++TV+DV ++ G+P+T G + G V++RD+ DP L Sbjct: 21 RDVATVSADDTVSDVAARISESDHNGFPVTD----GRHVEGFVSARDLLL--ADPDELLF 74 Query: 171 EVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKAR 225 +VMT D++ A + + DA ++ +S KLP++++ G LV +I D+ +++ Sbjct: 75 KVMT--EDLVVAHPEMDVTDAARVILRSGIQKLPVVDDAGNLVGIITNADVIRSQ 127 >UniRef50_Q2ACT2 Cluster: CBS:Phosphoesterase, RecJ-like:Polynucleotide adenylyltransferase region:Phosphoesterase, DHHA1; n=1; Halothermothrix orenii H 168|Rep: CBS:Phosphoesterase, RecJ-like:Polynucleotide adenylyltransferase region:Phosphoesterase, DHHA1 - Halothermothrix orenii H 168 Length = 865 Score = 51.6 bits (118), Expect = 5e-05 Identities = 32/108 (29%), Positives = 62/108 (57%), Gaps = 9/108 (8%) Query: 116 MGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID-FREGDP-HLSLKEVM 173 + P+ + +V + K G TG + +NG++ +G+ + RD++ +E D H +K M Sbjct: 319 VNPDTRIGEVEKILDKYGHTGIVVCENGEI----VGVFSKRDLNKVKEHDLLHSPVKGYM 374 Query: 174 TPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 + D+IT + T++ A ++ K G+LP+I DG+LV ++ R+D+ Sbjct: 375 S--TDVITIDVDETIRYAQKLMVKYDIGRLPVI-EDGKLVGIVTRSDI 419 >UniRef50_Q3AAR6 Cluster: PolyA polymerase family protein; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: PolyA polymerase family protein - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 864 Score = 51.2 bits (117), Expect = 6e-05 Identities = 32/112 (28%), Positives = 61/112 (54%), Gaps = 9/112 (8%) Query: 119 ENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID--FREGDPHLSLKEVMTPI 176 ++TV + + + G +G P+ + G +L+GI++ RD+D H +K M+ Sbjct: 323 DSTVEEARKIMVRYGHSGLPVLE----GDKLVGIISRRDVDKIIHHNLGHAPVKAYMS-- 376 Query: 177 NDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYP 228 + +T + +L++A +L K G+LP++ G+L+ +I+RTDL K P Sbjct: 377 KNPVTIEPEASLEEALRLLIKHDIGRLPVVEG-GKLIGIISRTDLLKQYHRP 427 >UniRef50_A7HLG0 Cluster: Polynucleotide adenylyltransferase region; n=2; Thermotogaceae|Rep: Polynucleotide adenylyltransferase region - Fervidobacterium nodosum Rt17-B1 Length = 883 Score = 50.8 bits (116), Expect = 8e-05 Identities = 36/156 (23%), Positives = 77/156 (49%), Gaps = 8/156 (5%) Query: 121 TVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID--FREGDPHLSLKEVMTPIND 178 ++ +V + + G +G P+ + G +L+GIVT + +D G +K +M+ + Sbjct: 334 SIEEVNKIMEITGHSGMPVVE----GNKLVGIVTKKTVDKALNHGLGKRPIKSIMS--SK 387 Query: 179 MITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQL 238 +ITA+L + ++ ++ G++PI++ + LV ++ R+D+ +A S P S ++ Sbjct: 388 LITAKLDTPVSVLRKLMIENDIGRIPILDENNILVGIVTRSDIIRAESSPKKSYLEKREE 447 Query: 239 LVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNS 274 + ERL + N + +I ++ NS Sbjct: 448 IKTTFNNISHLINERLSRRIVNLLRLIGFFGNEMNS 483 >UniRef50_A1HSL2 Cluster: Putative signal transduction protein with CBS domains; n=1; Thermosinus carboxydivorans Nor1|Rep: Putative signal transduction protein with CBS domains - Thermosinus carboxydivorans Nor1 Length = 214 Score = 50.8 bits (116), Expect = 8e-05 Identities = 40/128 (31%), Positives = 63/128 (49%), Gaps = 24/128 (18%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDP------ 165 +PV + P TVAD E + + F P+ GRL+GIVT RD+ RE P Sbjct: 10 NPVTISPTATVADASELMRTHKFRRLPVVDK----GRLVGIVTDRDL--REVSPSPATTL 63 Query: 166 ----------HLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVAL 215 + +KEVM ++IT + T+++A ++ +K G L ++N G +V + Sbjct: 64 SIFELNYLLAKMQVKEVMR--TNVITIRDDATIEEAALLMYNNKIGGLVVVNAAGAVVGI 121 Query: 216 IARTDLKK 223 I TD+ K Sbjct: 122 ITETDIFK 129 >UniRef50_A6TR64 Cluster: Polynucleotide adenylyltransferase region precursor; n=1; Alkaliphilus metalliredigens QYMF|Rep: Polynucleotide adenylyltransferase region precursor - Alkaliphilus metalliredigens QYMF Length = 875 Score = 50.4 bits (115), Expect = 1e-04 Identities = 30/104 (28%), Positives = 57/104 (54%), Gaps = 9/104 (8%) Query: 122 VADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID--FREGDPHLSLKEVMTPINDM 179 + +V + + G TG P+ + G ++IGI++ D+D G H +K MT ++ Sbjct: 326 IQEVNKIMLRYGHTGMPVLE----GDQMIGIISRTDVDKAIIHGLGHAPVKGFMT--KNV 379 Query: 180 ITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 T TL++ N +L ++ G+LP++ D +L+ ++ RTD+ K Sbjct: 380 KTINPSTTLKEMNLLLTRNNIGRLPVV-EDNQLIGIVTRTDVLK 422 >UniRef50_A4J3L2 Cluster: Polynucleotide adenylyltransferase region precursor; n=2; Peptococcaceae|Rep: Polynucleotide adenylyltransferase region precursor - Desulfotomaculum reducens MI-1 Length = 907 Score = 50.4 bits (115), Expect = 1e-04 Identities = 34/132 (25%), Positives = 68/132 (51%), Gaps = 11/132 (8%) Query: 93 EYQANEVHKVKKYKHGFIRDPVCMG-PENTVADVLEAKKKNGFTGYPITQNGKLGGRLIG 151 E ++H + K + PV M PE T+ + + + G TG P+ ++GKL G Sbjct: 299 ELVKEKIHPLLTVKD-IMSSPVKMVFPETTIEEAGKIMLRYGHTGLPVIKDGKLS----G 353 Query: 152 IVTSRDID--FREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINND 209 +++ RD++ G H +K MT ++IT Q + + D ++ + G+LP++ + Sbjct: 354 VISRRDVEKATHHGLGHAPVKGYMT--TNVITVQKDMNIHDVQDLMIEKDIGRLPVVEGN 411 Query: 210 GELVALIARTDL 221 ++ +++RTD+ Sbjct: 412 -MVIGIVSRTDV 422 >UniRef50_Q31MV1 Cluster: CBS; n=3; Synechococcus elongatus|Rep: CBS - Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2) Length = 859 Score = 50.0 bits (114), Expect = 1e-04 Identities = 33/108 (30%), Positives = 57/108 (52%), Gaps = 10/108 (9%) Query: 122 VADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID---FREGDPHLSLKEVMTPIND 178 + +V++ + G+P+TQ G L +GIVTS D+D + + L E+MTP Sbjct: 455 LTEVIQQFNRTHHRGFPVTQKGAL----VGIVTSSDLDEQTLKGKGESVRLSEIMTP--H 508 Query: 179 MITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARS 226 +T TL Y+L + + +LP+++ +LV +I R D+ +A S Sbjct: 509 PLTVAPQDTLAHVLYVLNRFQISRLPVVDG-RKLVGIITRADIIRAES 555 >UniRef50_Q58629 Cluster: Uncharacterized protein MJ1232; n=6; Methanococcales|Rep: Uncharacterized protein MJ1232 - Methanococcus jannaschii Length = 296 Score = 50.0 bits (114), Expect = 1e-04 Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 6/114 (5%) Query: 110 IRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSL 169 I++ + P T+ + + + +G P+ N KL +G+++ DI + + Sbjct: 177 IKEVWTINPNCTLRETAKLFAEKYISGAPVVDNDKL----VGVISLHDIAENIDNIDKKV 232 Query: 170 KEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 KEVM D+IT + DA I+ K+ G+L I++++ ++V +I RTD+ K Sbjct: 233 KEVMR--RDVITIHKDEKIYDALKIMNKNNVGRLVIVDDNNKIVGIITRTDILK 284 >UniRef50_A7HD42 Cluster: Putative signal transduction protein with CBS domains precursor; n=2; Anaeromyxobacter|Rep: Putative signal transduction protein with CBS domains precursor - Anaeromyxobacter sp. Fw109-5 Length = 166 Score = 49.6 bits (113), Expect = 2e-04 Identities = 33/115 (28%), Positives = 57/115 (49%), Gaps = 11/115 (9%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI-----DFREGDP 165 +D V +G + +A + +G P+ ++G RL+G+VT RD+ R G Sbjct: 30 KDLVTVGESDDLALAESLLRLSGIRHLPVVKDG----RLVGLVTQRDVLRSGQSGRSGAR 85 Query: 166 HLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTD 220 L++ EVMT D+ T + L A ++ + K G LP+ + +G LV ++ D Sbjct: 86 TLAVSEVMT--RDLTTVRPATALSQAARLMLERKYGCLPVCDEEGRLVGIVTEAD 138 >UniRef50_Q3E1R1 Cluster: CBS; n=3; Bacteria|Rep: CBS - Chloroflexus aurantiacus J-10-fl Length = 155 Score = 49.2 bits (112), Expect = 3e-04 Identities = 28/111 (25%), Positives = 59/111 (53%), Gaps = 9/111 (8%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK 170 ++ VC+ + V D +N +G P+ G L+G+VT D+ +EG ++K Sbjct: 9 KNVVCVTDDAAVEDAARLMTRNRISGLPVVNPQ---GMLVGLVTEHDLIAKEG---RTVK 62 Query: 171 EVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 E+MT +I+ ++ ++L + ++P++ N G++V +++R+DL Sbjct: 63 EIMT--RSVISVSPDTEVEQIQHLLTNQRIRRVPVVEN-GKVVGIVSRSDL 110 >UniRef50_Q2NBF2 Cluster: CBS; n=3; Bacteria|Rep: CBS - Erythrobacter litoralis (strain HTCC2594) Length = 147 Score = 49.2 bits (112), Expect = 3e-04 Identities = 30/122 (24%), Positives = 59/122 (48%), Gaps = 9/122 (7%) Query: 106 KHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---E 162 K+ +P C P +V + KN P+ + G L+G++T RDI R + Sbjct: 4 KNVMTSNPACCNPSTSVREAANLMVKNDCGEIPVVDDS---GTLVGVITDRDIACRCVAD 60 Query: 163 G-DPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 G S+++VMT + IT ++ D +E +K +LP+++ G+ ++++ D+ Sbjct: 61 GKSSDTSVEDVMT--SSPITVTPDTSVDDCRSKMEDNKVRRLPVVDESGKCCGIVSQADI 118 Query: 222 KK 223 + Sbjct: 119 AR 120 >UniRef50_Q898U3 Cluster: Inosine-5-monophosphate dehydrogenase related protein; n=3; Clostridium|Rep: Inosine-5-monophosphate dehydrogenase related protein - Clostridium tetani Length = 143 Score = 48.8 bits (111), Expect = 3e-04 Identities = 36/133 (27%), Positives = 66/133 (49%), Gaps = 15/133 (11%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR-----EGDP 165 +D V + E+TV + K++G PI GK ++GI+T RDI R E Sbjct: 9 KDIVSLQAEDTVEHAAQLMKEHGVGSLPICNEGK----IVGIITDRDIALRSVAMGESIQ 64 Query: 166 HLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKAR 225 + +++ +MT ++ IT ++ +A I+ K + +LP++ N LV +++ D+ Sbjct: 65 NQTVRNIMT--SNPITVSPNISATEAAEIMSKKQIRRLPVVENK-NLVGMVSLGDIS--- 118 Query: 226 SYPNASKDSNKQL 238 + PN + K L Sbjct: 119 TEPNLENSAGKAL 131 >UniRef50_Q8DLH3 Cluster: Tll0519 protein; n=4; Cyanobacteria|Rep: Tll0519 protein - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 907 Score = 48.4 bits (110), Expect = 4e-04 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 9/107 (8%) Query: 118 PENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID--FREGDPHLSLKEVM-T 174 PE +AD + G +G + G L+GI++ RD+D G H +K M Sbjct: 324 PETPIADAHRVLLRYGHSGLSVVS---AEGELLGIISRRDLDVALHHGFAHAPVKGYMKA 380 Query: 175 PINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 P+ T L + ++ + G+LP++N+ G+LV ++ RTD+ Sbjct: 381 PVR---TISPTTPLPEIQALMVQYDIGRLPVVNDQGDLVGIVTRTDV 424 >UniRef50_O66749 Cluster: Putative uncharacterized protein; n=1; Aquifex aeolicus|Rep: Putative uncharacterized protein - Aquifex aeolicus Length = 319 Score = 48.4 bits (110), Expect = 4e-04 Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 6/115 (5%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKE 171 +P+ + P T+ +V E K+ G P+ GK L+GIVT DI + + Sbjct: 203 NPITVSPNQTLKEVEEILSKHLIGGLPVVAKGK----LVGIVTKSDIQKVPSELREKKRV 258 Query: 172 VMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDG--ELVALIARTDLKKA 224 ++IT +L + I G+LP++ + G EL+ +I R D+ KA Sbjct: 259 YDVMSTNLITVTEEESLAEVLRIFSSKGIGRLPVVKHKGSSELIGIITRADIGKA 313 >UniRef50_A7RLX0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 209 Score = 48.4 bits (110), Expect = 4e-04 Identities = 22/30 (73%), Positives = 26/30 (86%) Query: 55 LLKAPLVSTPMDTVTEADMAISMALCGGIG 84 LLK P VS+PMDTVTE+ MA++MAL GGIG Sbjct: 154 LLKTPFVSSPMDTVTESAMAVAMALHGGIG 183 >UniRef50_UPI00015BB20C Cluster: putative signal transduction protein with CBS domains; n=1; Ignicoccus hospitalis KIN4/I|Rep: putative signal transduction protein with CBS domains - Ignicoccus hospitalis KIN4/I Length = 138 Score = 47.6 bits (108), Expect = 8e-04 Identities = 29/111 (26%), Positives = 58/111 (52%), Gaps = 6/111 (5%) Query: 113 PVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDF--REGDPHLSLK 170 P+ + P+ +V DV + ++G+ + ++ KL IGIVT RD+ + EG+ + LK Sbjct: 19 PLVVSPDESVVDVAKKMLEHGYGSALVIEDDKL----IGIVTERDLLYALSEGEEGVKLK 74 Query: 171 EVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 D I+ + + +A I++ + LP++++ G V ++A D+ Sbjct: 75 ASDVMTEDPISVKAKTDIMEAIKIMKDANVRHLPVVDDKGRPVGVVAFRDI 125 >UniRef50_Q2JHW1 Cluster: PolyA polymerase family protein; n=3; Synechococcus|Rep: PolyA polymerase family protein - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 908 Score = 47.6 bits (108), Expect = 8e-04 Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 8/106 (7%) Query: 118 PENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID--FREGDPHLSLKEVMTP 175 PE T+ + + G +G + GRL+G+++ RDID G H +K MT Sbjct: 336 PEITIDEAQRVLLRYGHSGLVVVD---AQGRLVGVISRRDIDIALHHGFGHAPVKGYMT- 391 Query: 176 INDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 D+ T L + ++ + G+LP++ DG+LV ++ RTD+ Sbjct: 392 -TDVKTLSPDTPLAEIQRLMVQWDIGRLPVL-QDGQLVGIVTRTDV 435 >UniRef50_Q8TWX4 Cluster: Prdicted regulatory protein consisting of a uncharacterized conserved domain fused to a CBS domain; n=7; Euryarchaeota|Rep: Prdicted regulatory protein consisting of a uncharacterized conserved domain fused to a CBS domain - Methanopyrus kandleri Length = 501 Score = 47.6 bits (108), Expect = 8e-04 Identities = 28/108 (25%), Positives = 54/108 (50%), Gaps = 5/108 (4%) Query: 114 VCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVM 173 V P+ ++ DV + P+ GR++GIVTS DI + LK++M Sbjct: 391 VTASPDESIEDVARRLIEKEINHIPVVDEE---GRIVGIVTSWDIAAAVAEGKRRLKDIM 447 Query: 174 TPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 T D+IT + ++ +A +++ LP+++ + +V ++ RTD+ Sbjct: 448 T--EDVITIRPHESVDEALRRMDRHNISCLPVVDGENRVVGIVTRTDI 493 >UniRef50_Q8R911 Cluster: CBS domains; n=3; Thermoanaerobacter|Rep: CBS domains - Thermoanaerobacter tengcongensis Length = 435 Score = 46.8 bits (106), Expect = 0.001 Identities = 36/116 (31%), Positives = 56/116 (48%), Gaps = 8/116 (6%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKE 171 +PV M P+ TV D + T +P+ + G L+G+VTSRD+ D + + Sbjct: 196 NPVYMTPQQTVRDWKRLYAETKHTRFPVVDSK---GMLVGMVTSRDVATASDDDRIG--D 250 Query: 172 VMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSY 227 +MTP +T TL A +++ LP+ EL+ LI+R D+ KA Y Sbjct: 251 IMTPNPVFVTDT--TTLSYAAHLMIWWNVEILPVTRGK-ELIGLISREDVIKALHY 303 >UniRef50_Q6Q303 Cluster: IMP dehydrogenase; n=1; Synechococcus sp. PCC 7002|Rep: IMP dehydrogenase - Synechococcus sp. (strain PCC 7002) (Agmenellum quadruplicatum) Length = 258 Score = 46.8 bits (106), Expect = 0.001 Identities = 25/51 (49%), Positives = 32/51 (62%) Query: 291 IQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAV 341 I VV GN VT A L+ AG A+ VG+G G+ C ++ V+ G PQATAV Sbjct: 188 IPVVLGNCVTYDAALELMRAGAAAVLVGIGPGAACTSRGVLGVGVPQATAV 238 >UniRef50_A0LGS9 Cluster: CBS domain containing membrane protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: CBS domain containing membrane protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 225 Score = 46.8 bits (106), Expect = 0.001 Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 20/126 (15%) Query: 114 VCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI--------------- 158 V +GP + + + E K+ F P+ RL+GIVT RDI Sbjct: 12 VTVGPNDGILETRELLAKSSFRHLPVVDEEN---RLVGIVTDRDIRSAMPSVFLDENETL 68 Query: 159 DFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIAR 218 RE + +K++MT + +T TL+DA ++++ + G P+++ +G+L +++ Sbjct: 69 KERERLAQMKIKDIMT--KNPVTVNPANTLEDAILLMQRMRVGAFPVVDREGKLRGMLSI 126 Query: 219 TDLKKA 224 DL +A Sbjct: 127 RDLVRA 132 >UniRef50_Q96YR0 Cluster: Putative uncharacterized protein ST2113; n=2; Sulfolobaceae|Rep: Putative uncharacterized protein ST2113 - Sulfolobus tokodaii Length = 268 Score = 46.8 bits (106), Expect = 0.001 Identities = 38/172 (22%), Positives = 82/172 (47%), Gaps = 12/172 (6%) Query: 59 PLVSTPMDTVTEADMAISMALCGGI-GIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMG 117 PL ++ + +A + I ++ G I G+I + +Y A + + K ++P+ + Sbjct: 83 PLEASQIMIEKKAPLLIVISDTGKILGMIIKSDLAQYYATLIRGIHKVSEYMSKNPITVN 142 Query: 118 PENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDF-----REGDPHLSLKEV 172 ++T+ +V + + + NGK ++G +T+ D+ + + D + +KEV Sbjct: 143 KDSTLDEVTKIILEKNIGRLIVEDNGK----ILGTITTTDLLYLAPVLKFKDLKIKVKEV 198 Query: 173 MTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 MTP ++ L A ++ K +PI++ +GEL ++ TD+ +A Sbjct: 199 MTP--TIVVMDENEDLNYAAKLMANRKVKGIPIVSANGELKGIVTTTDIVRA 248 >UniRef50_Q9X175 Cluster: Inosine-5-monophosphate dehydrogenase-related protein; n=4; Thermotogaceae|Rep: Inosine-5-monophosphate dehydrogenase-related protein - Thermotoga maritima Length = 321 Score = 46.4 bits (105), Expect = 0.002 Identities = 30/112 (26%), Positives = 61/112 (54%), Gaps = 7/112 (6%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHL--SL 169 D + + P+ T+ V E + +G P+ + K R++GIV+ DI ++ S+ Sbjct: 25 DVIYVTPDKTLLHVKEIMRIKRISGVPVVDDKK---RVVGIVSLEDIIKALEGSYIKDSV 81 Query: 170 KEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 ++ MT +++ + TLQDA EK G+ P+++++G+LV ++ + D+ Sbjct: 82 EKRMT--KNVVCLKETDTLQDAVKTFEKYGYGRFPVVDDEGKLVGIVTKHDI 131 >UniRef50_A5IN38 Cluster: CBS domain containing protein; n=2; Thermotoga|Rep: CBS domain containing protein - Thermotoga petrophila RKU-1 Length = 215 Score = 46.4 bits (105), Expect = 0.002 Identities = 31/127 (24%), Positives = 64/127 (50%), Gaps = 20/127 (15%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDP----- 165 R+P+ + PE + ++ L+ K+N + ++ K+ +GIVT +D+ + Sbjct: 9 RNPITIAPETSFSEALKLMKQNKIKRLIVMKDEKI----VGIVTEKDLLYASPSKATTLN 64 Query: 166 ---------HLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALI 216 L ++E+MT +++T ++DA I+E+ LP++++ G LV +I Sbjct: 65 IWELHYLLSKLKIEEIMT--KNVVTVNENAPIEDAARIMEEKDISGLPVVDDAGRLVGII 122 Query: 217 ARTDLKK 223 +TD+ K Sbjct: 123 TQTDIFK 129 >UniRef50_Q2ACR8 Cluster: CBS; n=1; Halothermothrix orenii H 168|Rep: CBS - Halothermothrix orenii H 168 Length = 262 Score = 46.0 bits (104), Expect = 0.002 Identities = 28/111 (25%), Positives = 56/111 (50%), Gaps = 7/111 (6%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK 170 +DP+ + PE TV + + N + ++ L +GI+T D+ + D + + Sbjct: 9 KDPITISPETTVVEAEKLMSINNIGRLIVVEDEGL----VGILTDGDLVIQH-DLNAPID 63 Query: 171 EVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 + M+ ++IT T+Q+A +L G LP+++ DG+LV ++ D+ Sbjct: 64 KFMS--REVITISQNATVQEAAKVLSDHGIGGLPVLDEDGKLVGIVTADDI 112 >UniRef50_A4M812 Cluster: Polynucleotide adenylyltransferase region; n=1; Petrotoga mobilis SJ95|Rep: Polynucleotide adenylyltransferase region - Petrotoga mobilis SJ95 Length = 885 Score = 46.0 bits (104), Expect = 0.002 Identities = 31/106 (29%), Positives = 56/106 (52%), Gaps = 9/106 (8%) Query: 121 TVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID--FREGDPHLSLKEVMTPIND 178 TV E + G +G P+ + KL +GIVT +DI+ + G + +K +M+ + Sbjct: 335 TVEIAHELMFQTGHSGLPVISDNKL----VGIVTKKDIEKAMKHGLKNAPVKAIMS--TN 388 Query: 179 MITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 + + +L I+ ++ G++P++ DG LV +I RTDL +A Sbjct: 389 LKVVDVETSLTQVRRIMAEADIGRIPVLK-DGILVGIITRTDLLRA 433 >UniRef50_O29915 Cluster: Putative uncharacterized protein; n=1; Archaeoglobus fulgidus|Rep: Putative uncharacterized protein - Archaeoglobus fulgidus Length = 362 Score = 46.0 bits (104), Expect = 0.002 Identities = 30/112 (26%), Positives = 61/112 (54%), Gaps = 9/112 (8%) Query: 114 VCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVM 173 V + PE TV++V++ K G+P+ + G RL+GI+T DI E P + +M Sbjct: 243 VTVTPEMTVSEVIDLILKTKHLGFPVVE----GERLVGIITLHDIIGVE--PEERVGNIM 296 Query: 174 TPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKAR 225 + +++ + +A I+ + G+LP++ + G +V +++R+DL + + Sbjct: 297 S--REVVAVSPNQSAFEAFKIMSEMGIGRLPVVEH-GRVVGIVSRSDLMRIK 345 >UniRef50_Q7NVZ6 Cluster: Putative uncharacterized protein; n=3; Proteobacteria|Rep: Putative uncharacterized protein - Chromobacterium violaceum Length = 343 Score = 45.6 bits (103), Expect = 0.003 Identities = 26/82 (31%), Positives = 41/82 (50%) Query: 320 GSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVM 379 G+ ++ +T A T + + + R ++P++A GG +I +LALGA V Sbjct: 130 GADALLVTGHEAAAHGGSVTTLVLIPAIRRASSLPIVAAGGFADGAGLIAALALGADAVA 189 Query: 380 MGSLLAGTSEAPGEYFFSDGVR 401 MGS LA T E+P D +R Sbjct: 190 MGSRLAMTRESPVHAQTKDMIR 211 >UniRef50_O26229 Cluster: Inosine-5'-monophosphate dehydrogenase related protein VII; n=2; Methanobacteriaceae|Rep: Inosine-5'-monophosphate dehydrogenase related protein VII - Methanobacterium thermoautotrophicum Length = 302 Score = 45.6 bits (103), Expect = 0.003 Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 8/113 (7%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI--DFREGDPHLS 168 RD V + P+ TV + G G PI ++ ++ G IVT DI G + Sbjct: 188 RDLVTLAPDITVKEAAARLSSLGIEGAPIVEDDEVKG----IVTLSDITASIAAGTEFMQ 243 Query: 169 LKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 + ++M+ ++IT + + DA ++ K G+L + +++G +I RTD+ Sbjct: 244 VSDIMS--KNIITVKQDTMIADAIEVMNKHNIGRLIVTDSEGRPTGIITRTDI 294 >UniRef50_A3CWH1 Cluster: CBS domain containing protein; n=1; Methanoculleus marisnigri JR1|Rep: CBS domain containing protein - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 251 Score = 45.6 bits (103), Expect = 0.003 Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 11/121 (9%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK 170 R+PV P+ V + +GFT +P+ Q + IGIV+ RD+ R G S+K Sbjct: 134 REPVTSTPDEPVHRIYSLIVASGFTAFPVVQKKE----TIGIVSRRDL-LRAGSVRTSVK 188 Query: 171 -EVMTPINDMITAQL-----GVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 + T + ++T + G T+ A+ ++ + LP+I+ +LV +I R D+ Sbjct: 189 NQADTTVERVMTTPVISVTPGDTIATASRLMVEHDVSMLPVIDEKKQLVGVIDRHDVLSG 248 Query: 225 R 225 R Sbjct: 249 R 249 >UniRef50_A7HCW1 Cluster: Putative signal-transduction protein with CBS domains; n=2; Anaeromyxobacter|Rep: Putative signal-transduction protein with CBS domains - Anaeromyxobacter sp. Fw109-5 Length = 145 Score = 45.2 bits (102), Expect = 0.004 Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 9/116 (7%) Query: 110 IRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---EGDPH 166 ++ +C P++T D K+ PI +G +T RD+ R +G P Sbjct: 8 MKSAMCCRPDDTARDCARLMKEENIGFVPICNESD---EPVGTITDRDLALRILADGRPS 64 Query: 167 -LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 L VMT ++++ +LG L+DA ++ + +K ++ + + +G+L +I+ +D+ Sbjct: 65 DAKLDGVMT--REVVSCRLGDDLRDAERLMREHRKSRIMVCDTEGKLQGVISLSDI 118 >UniRef50_A2ST08 Cluster: CBS domain containing protein; n=2; Methanomicrobiales|Rep: CBS domain containing protein - Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) Length = 512 Score = 45.2 bits (102), Expect = 0.004 Identities = 32/123 (26%), Positives = 61/123 (49%), Gaps = 8/123 (6%) Query: 103 KKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFRE 162 K+ + D + + TV DV+ G+P+ + GK+ +G +++RDI Sbjct: 4 KQVRDYMTHDVISIDASKTVGDVIRLIHTTDHDGFPVLRLGKV----VGYISARDII--- 56 Query: 163 GDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLK 222 G+ H S K + ITA+ VT+ + + ++ KLP+I D EL+ +I+ D+ Sbjct: 57 GE-HPSTKVELRMTRHPITARPDVTITEVARRIFRTGIQKLPVIGPDNELLGIISNMDVI 115 Query: 223 KAR 225 +++ Sbjct: 116 RSQ 118 >UniRef50_A6SYJ5 Cluster: Inosine-5'-monophosphate dehydrogenase; n=1; Janthinobacterium sp. Marseille|Rep: Inosine-5'-monophosphate dehydrogenase - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 139 Score = 44.8 bits (101), Expect = 0.006 Identities = 32/114 (28%), Positives = 59/114 (51%), Gaps = 10/114 (8%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---EGDPHLS 168 D + PE T+ D + K+ F P+ +N R+IG ++ RDI R EG P + Sbjct: 11 DVQVISPEATIQDAAKKMKEGNFGMLPVHEND----RMIGSISDRDIVIRAVAEGKPSST 66 Query: 169 -LKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 +++VMT ++ A +L + ++ + + +LPI+N+ LV ++A D+ Sbjct: 67 KVRDVMT--KGIVWAFEDSSLSEGVRLMSQHQVRRLPIVNSQKRLVGIVAIGDV 118 >UniRef50_A5WFG6 Cluster: FMN-dependent alpha-hydroxy acid dehydrogenase; n=1; Psychrobacter sp. PRwf-1|Rep: FMN-dependent alpha-hydroxy acid dehydrogenase - Psychrobacter sp. PRwf-1 Length = 352 Score = 44.8 bits (101), Expect = 0.006 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 7/105 (6%) Query: 288 YPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASY 347 Y + V+ +V A+ +D G + V G T P A+ +VA Sbjct: 218 YTSLPVLIKGIVNAEDAQRALDIGASGIIVSNHGGRKLDTAP------PTIEALQRVAER 271 Query: 348 ARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPG 392 H VPV+ DGGI+ ++K+LALGA V++G +A A G Sbjct: 272 VDH-RVPVLIDGGIRRGTDVLKALALGADAVLLGKPIAQALGAAG 315 >UniRef50_A1VAU2 Cluster: CBS domain containing protein; n=3; Desulfovibrio|Rep: CBS domain containing protein - Desulfovibrio vulgaris subsp. vulgaris (strain DP4) Length = 256 Score = 44.8 bits (101), Expect = 0.006 Identities = 33/129 (25%), Positives = 63/129 (48%), Gaps = 23/129 (17%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDP----- 165 R+ + + P+ ++ + K+NGF P+ G+LIGIV+ RDI +E P Sbjct: 38 RNVITVTPDTSMMKASKLMKENGFRRLPVLDGN---GKLIGIVSDRDI--KEASPSKATT 92 Query: 166 -----------HLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVA 214 + +K++MT D I Q T++ ++ + G +P+++ +G+LV Sbjct: 93 LDMHELYYLLSEIKVKDIMT--RDPICVQPDETVERVALLMIEKHIGGMPVVDEEGQLVG 150 Query: 215 LIARTDLKK 223 +I +D+ K Sbjct: 151 IITDSDIFK 159 Score = 35.5 bits (78), Expect = 3.4 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 3/55 (5%) Query: 104 KYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI 158 K K RDP+C+ P+ TV V + G P+ G+L+GI+T DI Sbjct: 106 KVKDIMTRDPICVQPDETVERVALLMIEKHIGGMPVVDE---EGQLVGIITDSDI 157 >UniRef50_A7D0I7 Cluster: Peptidase M50; n=4; Halobacteriaceae|Rep: Peptidase M50 - Halorubrum lacusprofundi ATCC 49239 Length = 394 Score = 44.8 bits (101), Expect = 0.006 Identities = 28/106 (26%), Positives = 55/106 (51%), Gaps = 4/106 (3%) Query: 119 ENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPIND 178 + +VAD++ + TGYP+ G L G ++ + +R + E D + + +VM + Sbjct: 266 DTSVADLMSRMFEERHTGYPVLHGGNLVG-MVTLEDARSVRDVERDAY-QVADVME--TE 321 Query: 179 MITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 ++ A ++++ G+LP+++ ELV LI+R+DL A Sbjct: 322 VVGVGPEADAMTALQTMQENGVGRLPVVDRSDELVGLISRSDLMTA 367 >UniRef50_A0B5X6 Cluster: Putative signal-transduction protein with CBS domains; n=1; Methanosaeta thermophila PT|Rep: Putative signal-transduction protein with CBS domains - Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrixthermophila (strain DSM 6194 / PT)) Length = 185 Score = 44.8 bits (101), Expect = 0.006 Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 7/86 (8%) Query: 146 GGRLIGIVTSRD----IDFREGDPHLS-LKEVMTPINDMITAQLGVTLQDANYILEKSKK 200 G + IGI+T RD + R DP S + +VM + +I +L+DA ++ KS Sbjct: 44 GAKPIGIITERDLVKKVVARAEDPRKSRVGDVMN--SPLIKIHPDASLRDAAELMLKSGV 101 Query: 201 GKLPIINNDGELVALIARTDLKKARS 226 +LP+I++DG+LV +I TDL S Sbjct: 102 KRLPVISDDGKLVGIITDTDLVSGAS 127 >UniRef50_Q67L31 Cluster: Glycine betaine/carnitine/choline ABC transporter ATP-binding protein; n=4; Firmicutes|Rep: Glycine betaine/carnitine/choline ABC transporter ATP-binding protein - Symbiobacterium thermophilum Length = 376 Score = 44.4 bits (100), Expect = 0.007 Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 6/112 (5%) Query: 110 IRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSL 169 I DPV GPE +A+ + ++ + GRL+GIVT+R ++ R H +L Sbjct: 256 IPDPVTAGPEYGIAEAVATMRRRRVNSVLVVDGD---GRLLGIVTARAVE-RGLASHRTL 311 Query: 170 KEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 E+M + VT +LE+ + LP+++ G L L+ T L Sbjct: 312 GEIMETRLTTVLPHQPVTHAVQRMLLERLE--FLPVVDEQGRLQGLVTNTSL 361 >UniRef50_Q3AFS5 Cluster: CBS/GGDEF domain protein; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: CBS/GGDEF domain protein - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 271 Score = 44.4 bits (100), Expect = 0.007 Identities = 32/122 (26%), Positives = 61/122 (50%), Gaps = 8/122 (6%) Query: 102 VKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR 161 +K+ + R+PV + P ++ D E + G P+ +N K LIGI+TS+D+ F Sbjct: 2 IKQVREVMTRNPVTIEPYRSLWDAKELMRSQRIGGLPVVENEK----LIGIITSKDLIFY 57 Query: 162 EGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 + L + + MT + + + L DA + ++ +LP+I+ G L +I R + Sbjct: 58 P-ENRLVI-DAMT--EEPVVIEEKAYLFDAYQKMLENNIERLPVIDESGALTGIITRKVI 113 Query: 222 KK 223 ++ Sbjct: 114 ER 115 >UniRef50_A5N386 Cluster: Putative uncharacterized protein; n=1; Clostridium kluyveri DSM 555|Rep: Putative uncharacterized protein - Clostridium kluyveri DSM 555 Length = 141 Score = 44.4 bits (100), Expect = 0.007 Identities = 27/120 (22%), Positives = 60/120 (50%), Gaps = 7/120 (5%) Query: 104 KYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREG 163 K ++ + + P++T+ + +N P+ Q GK+ IGI+T RDI R Sbjct: 2 KVENVMTKSVASLNPDDTIDKAAQVMMENNIGSLPVCQQGKI----IGILTDRDISIRAM 57 Query: 164 DPHLSLKEVMTPI--NDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 S + + I ++ +TA + ++D + I+ + + ++P++ N+ +V +++ DL Sbjct: 58 GNKASNSKTVRDIMSSNPVTASPDMDVKDVSRIMSERQIRRVPVVENN-NVVGIVSLGDL 116 >UniRef50_A2SQ80 Cluster: CBS domain containing protein; n=4; Methanomicrobiales|Rep: CBS domain containing protein - Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) Length = 284 Score = 44.4 bits (100), Expect = 0.007 Identities = 29/98 (29%), Positives = 53/98 (54%), Gaps = 7/98 (7%) Query: 124 DVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQ 183 DVL K+ G +G P+ + + +L+GIVT +DI + + ++L P+ T + Sbjct: 25 DVLRILKRTGISGVPVVKGPEK--KLLGIVTRKDILRKPEETQVALLMSSEPL----TIR 78 Query: 184 LGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 VTL +A I+ K +LP++ D L+ +++ +DL Sbjct: 79 PEVTLSEAAEIMTKMNVRRLPVVEGD-NLIGILSVSDL 115 >UniRef50_A2BJ31 Cluster: Predicted transcriptional regulator; n=1; Hyperthermus butylicus DSM 5456|Rep: Predicted transcriptional regulator - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 296 Score = 44.4 bits (100), Expect = 0.007 Identities = 31/112 (27%), Positives = 57/112 (50%), Gaps = 7/112 (6%) Query: 114 VCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID--FREGDPHLSLKE 171 + + P+ T+ D + + G P+ + GRLIGI+T DI EG ++KE Sbjct: 184 ITIEPDATIKDAAKLMIERRVKGLPVIDSR---GRLIGIITQTDIAKAVAEGRIDATVKE 240 Query: 172 VMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 M+ +IT + + DA ++ G+L + +++G+ + +I RTD+ K Sbjct: 241 YMS--FPVITIRSDEDIGDAIELMNLRDIGRLVVTDSEGKPIGIITRTDILK 290 Score = 39.9 bits (89), Expect = 0.16 Identities = 27/81 (33%), Positives = 48/81 (59%), Gaps = 7/81 (8%) Query: 145 LGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDA-NYILEKSKKGKL 203 L + IGI +R I P + + E+ + I ++IT + T++DA ++E+ KG L Sbjct: 154 LATKQIGIKITRLISV----PRIPVGEIAS-IGNIITIEPDATIKDAAKLMIERRVKG-L 207 Query: 204 PIINNDGELVALIARTDLKKA 224 P+I++ G L+ +I +TD+ KA Sbjct: 208 PVIDSRGRLIGIITQTDIAKA 228 >UniRef50_Q9WZH4 Cluster: TRNA nucleotidyl transferase-related protein; n=2; Thermotoga|Rep: TRNA nucleotidyl transferase-related protein - Thermotoga maritima Length = 863 Score = 44.0 bits (99), Expect = 0.010 Identities = 27/106 (25%), Positives = 56/106 (52%), Gaps = 9/106 (8%) Query: 121 TVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID--FREGDPHLSLKEVMTPIND 178 T+ +V K+ G +G+P+ + G RL+GIVT + ++ G +K +M+ + Sbjct: 320 TIKEVDRLMKQTGHSGFPVVE----GNRLVGIVTKKAVEKAMNHGLGDRPVKSIMS--TN 373 Query: 179 MITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 ++ A + ++ + G++PI+ N G LV ++ R+D+ +A Sbjct: 374 LVVASPDTPVTRLRELMVEHAIGRIPILEN-GILVGIVTRSDVLRA 418 >UniRef50_A1CVD5 Cluster: 2-nitropropane dioxygenase family oxidoreductase, putative; n=1; Neosartorya fischeri NRRL 181|Rep: 2-nitropropane dioxygenase family oxidoreductase, putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 345 Score = 44.0 bits (99), Expect = 0.010 Identities = 49/168 (29%), Positives = 77/168 (45%), Gaps = 15/168 (8%) Query: 233 DSNKQLLVGAAIGTR--DTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPE 290 DSN L +G T DT ++ LVN V V + + + ++I+ ++ T + Sbjct: 77 DSNTLLPIGIGCLTMKSDTWKDNFVQLVNEYRPVAVWLFAYTHRSQHAELIQALQNTGKD 136 Query: 291 --IQVVGGNVVTRMQAKNLIDAGVDALRV-GMGSGSICITQEVMACGCPQATAVYQVASY 347 ++V+ V T A+ ID G D L V G +G Q G T + +VA Sbjct: 137 WGLKVIV-QVGTVESAREAIDDGADILSVQGSDAGGHQFKQ-----GASLMTLLPEVADM 190 Query: 348 AR----HFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAP 391 R N+P++A GGI + +L LGAS ++MG+ T+E P Sbjct: 191 VRSEYPEKNIPLLAAGGIMDGRGVAAALMLGASGIVMGTGFLCTTECP 238 >UniRef50_A2BLX1 Cluster: Conserved archaeal protein; n=1; Hyperthermus butylicus DSM 5456|Rep: Conserved archaeal protein - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 153 Score = 44.0 bits (99), Expect = 0.010 Identities = 35/109 (32%), Positives = 55/109 (50%), Gaps = 10/109 (9%) Query: 118 PENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---EG-DPHLSL-KEV 172 P++TV D K G + + K G ++GI+T DI R G DP +L ++V Sbjct: 27 PDDTVVDAARKMAKYSI-GSVVVVDDK--GTILGILTEGDIVRRVVARGLDPSRTLVRDV 83 Query: 173 MTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 MT + +T TL A +++ G LP++N G LV +I +TD+ Sbjct: 84 MT--TNPVTIYSDATLAAAAEYMKRKGIGHLPVVNEQGRLVGIITKTDI 130 >UniRef50_Q67NF3 Cluster: Putative poly A polymerase; n=1; Symbiobacterium thermophilum|Rep: Putative poly A polymerase - Symbiobacterium thermophilum Length = 890 Score = 43.6 bits (98), Expect = 0.013 Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 8/102 (7%) Query: 122 VADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID--FREGDPHLSLKEVMTPINDM 179 + D ++G TG P+ GR++G+V+ RD++ R G H +K VM + + Sbjct: 338 IRDAERLMLRHGHTGLPVVDEQ---GRVVGVVSLRDVEKARRHGLEHAPVKSVMR--SQV 392 Query: 180 ITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 I + ++ + G++P++ DG LV +I R+D+ Sbjct: 393 IAVHPDTPADEVQELMIERDIGRVPVV-ADGNLVGIITRSDI 433 >UniRef50_A5V6U0 Cluster: FMN-dependent alpha-hydroxy acid dehydrogenase; n=1; Sphingomonas wittichii RW1|Rep: FMN-dependent alpha-hydroxy acid dehydrogenase - Sphingomonas wittichii RW1 Length = 395 Score = 43.6 bits (98), Expect = 0.013 Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 8/115 (6%) Query: 279 KMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQA 338 K I +++ + V+ G ++ R A +DAG DAL V G + P A Sbjct: 239 KDIAWLRNQWKGRLVIKG-ILDRRDATMALDAGADALVVSNHGG------RQLDGVAPTA 291 Query: 339 TAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGE 393 A+ +A A P++ DGG++S ++K+L LGA V++G A + A GE Sbjct: 292 VALPAIAR-AVGGRAPLLVDGGVRSGQDVLKALLLGADGVLIGRAWAYAAAAGGE 345 >UniRef50_A1HPJ0 Cluster: Sigma54 specific transcriptional regulator, Fis family; n=6; Bacteria|Rep: Sigma54 specific transcriptional regulator, Fis family - Thermosinus carboxydivorans Nor1 Length = 700 Score = 43.6 bits (98), Expect = 0.013 Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 9/162 (5%) Query: 114 VCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVT-SRDIDFREGDPHLSLK-- 170 V + P T+ G G P+ G+LIG+VT S I D +L+ Sbjct: 12 VTVTPGMTLQQTARIFDSVGIDGAPVVD---ANGKLIGLVTKSHLIKALAADNFYNLRVG 68 Query: 171 EVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNA 230 +VMTP D+ T Q T+Q+ + G+ P+++ + + I RTDL K S + Sbjct: 69 DVMTP--DVFTLQENTTIQELQQNNRIFRYGRFPVVDGENRPIGFITRTDLVKYLSERSL 126 Query: 231 -SKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQ 271 D + +L G T+ + + L N + I SS+ Sbjct: 127 FLADEMQAVLNSVCNGVIVTNADGIVTLFNPAAEYITGLSSE 168 >UniRef50_Q0W4Y8 Cluster: Putative uncharacterized protein; n=1; uncultured methanogenic archaeon RC-I|Rep: Putative uncharacterized protein - Uncultured methanogenic archaeon RC-I Length = 138 Score = 43.6 bits (98), Expect = 0.013 Identities = 34/125 (27%), Positives = 65/125 (52%), Gaps = 11/125 (8%) Query: 104 KYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR-- 161 K K + C+ ++T AD AK KN TG I +G + GIVT R I + Sbjct: 2 KIKDVMTSEIACVDTKSTAADAA-AKMKNQNTGTVIVVDGD---SVKGIVTDRQIAIKAV 57 Query: 162 --EGDP-HLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIAR 218 + DP + + ++MT D++ + + DA + ++K +LP++N++ +LV +++ Sbjct: 58 AEKKDPKNTPVSDIMT--KDIVGCRENDDIFDALKTMGENKVRRLPVVNDNSQLVGIVSI 115 Query: 219 TDLKK 223 +D+ + Sbjct: 116 SDIAR 120 >UniRef50_Q835K5 Cluster: CBS domain protein; n=6; Bacilli|Rep: CBS domain protein - Enterococcus faecalis (Streptococcus faecalis) Length = 439 Score = 43.2 bits (97), Expect = 0.017 Identities = 29/104 (27%), Positives = 56/104 (53%), Gaps = 7/104 (6%) Query: 121 TVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMI 180 T+AD + + +P+ N KL RL+GIVT++D+ + HL++ +VMT +++ Sbjct: 209 TIADYQALSESTHHSRFPVV-NKKL--RLVGIVTAKDVIGK--SEHLTVDKVMTKDPNVV 263 Query: 181 TAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 + V I + + +P++ +D LV +++R D+ KA Sbjct: 264 KKMMSVASVSHQMIWDGLE--VMPVVEDDLALVGIVSRQDVMKA 305 >UniRef50_Q1IKU8 Cluster: 2-nitropropane dioxygenase, NPD; n=2; Bacteria|Rep: 2-nitropropane dioxygenase, NPD - Acidobacteria bacterium (strain Ellin345) Length = 356 Score = 43.2 bits (97), Expect = 0.017 Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 4/118 (3%) Query: 275 TYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRV-GMGSGSICITQEV-MA 332 T+ I + I+ +V G T + + L AGVDA+ G +G T +V Sbjct: 131 TFGIPLASAIQRAQKRGILVFGTATTVREGQLLASAGVDAIVAQGAEAGGQRGTFDVSFE 190 Query: 333 CGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEA 390 G A+ VA A +PVIA GGI + I + L LGAS V +G++ T EA Sbjct: 191 EGLVPLRAL--VAGLANAVALPVIASGGIMNGREIAEMLRLGASAVQLGTVFLCTPEA 246 >UniRef50_A5D444 Cluster: Putative uncharacterized protein; n=1; Pelotomaculum thermopropionicum SI|Rep: Putative uncharacterized protein - Pelotomaculum thermopropionicum SI Length = 281 Score = 43.2 bits (97), Expect = 0.017 Identities = 30/102 (29%), Positives = 55/102 (53%), Gaps = 9/102 (8%) Query: 120 NTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDM 179 ++VA +K+G G P+ + KL GI+TSRD+ R P+ + + M+ ++ Sbjct: 19 DSVAKAALLMEKHGIGGLPVLNDDKL----CGIITSRDV--RRAHPNRIVADAMS--KNV 70 Query: 180 ITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 I+ +L +A I+ + K +LP++ D LV +I +TD+ Sbjct: 71 ISVNSNESLLNAMNIIGEKKVERLPVL-EDCRLVGIITKTDI 111 >UniRef50_Q2H129 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 249 Score = 43.2 bits (97), Expect = 0.017 Identities = 24/60 (40%), Positives = 33/60 (55%) Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369 AG++ L++GMG GS CI QEVM A V +A + P + G IQ+VG + K Sbjct: 83 AGLEGLKIGMGRGSACIIQEVMKVRLLPGEAGDSVPPFAGNPAKPKVRVGSIQNVGPMDK 142 >UniRef50_Q8TX12 Cluster: CBS-domain-containing protein; n=3; Euryarchaeota|Rep: CBS-domain-containing protein - Methanopyrus kandleri Length = 138 Score = 43.2 bits (97), Expect = 0.017 Identities = 25/65 (38%), Positives = 39/65 (60%), Gaps = 2/65 (3%) Query: 160 FREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIART 219 FRE ++E+MT D ITA V + +A I+ K G LP+++++G L+ L+ RT Sbjct: 3 FREKLRGCKVEELMT--KDPITASPQVGVIEAFEIMLKHDVGALPVVDDEGRLIGLVTRT 60 Query: 220 DLKKA 224 DL +A Sbjct: 61 DLGRA 65 Score = 40.3 bits (90), Expect = 0.12 Identities = 30/118 (25%), Positives = 59/118 (50%), Gaps = 12/118 (10%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR----EGDPH 166 +DP+ P+ V + E K+ P+ + GRLIG+VT D+ E +P Sbjct: 18 KDPITASPQVGVIEAFEIMLKHDVGALPVVDDE---GRLIGLVTRTDLGRALLEDEYEPG 74 Query: 167 LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKG---KLPIINNDGELVALIARTDL 221 +++EVM D++ TL +A + + +G +LP+++++ +LV ++ D+ Sbjct: 75 TTVEEVME--RDVVVVHPDDTLLEALKRMTSAPEGIYNQLPVVDDEEKLVGILTDGDI 130 >UniRef50_Q57976 Cluster: Methylated protein MJ0556; n=2; Methanocaldococcus jannaschii|Rep: Methylated protein MJ0556 - Methanococcus jannaschii Length = 174 Score = 43.2 bits (97), Expect = 0.017 Identities = 36/143 (25%), Positives = 62/143 (43%), Gaps = 11/143 (7%) Query: 98 EVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRD 157 E+ K++ D + PE T+ ++ + K+ +G P+ + G +IG +T R+ Sbjct: 18 ELQKIRVKDVMISGDVIITTPEKTIKEIFDEMIKHNISGMPVVDD---RGVMIGFITLRE 74 Query: 158 I-DFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINND------G 210 I + P+L++ EVM TA + I K +LP+IN G Sbjct: 75 IRKYMTSHPYLNVGEVMLKNPPYTTADEDIITAFEKMIESNKKLDQLPVINTKYPEKILG 134 Query: 211 ELVALIARTDLKKARSYPNASKD 233 +L +I D+ K Y N K+ Sbjct: 135 KLEGIIFMEDIIKL-LYENIIKE 156 >UniRef50_Q97M06 Cluster: Deoxyphosphogluconate aldolase; n=1; Clostridium acetobutylicum|Rep: Deoxyphosphogluconate aldolase - Clostridium acetobutylicum Length = 208 Score = 42.7 bits (96), Expect = 0.022 Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 3/102 (2%) Query: 255 KLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDA 314 K L++ G+D I + S ++ K+IK +K+ YP + G VVT QAK ID G D Sbjct: 31 KRLISQGIDTIEVTYSVKDAG---KLIKALKDEYPNSLIGAGTVVTAAQAKEAIDYGADF 87 Query: 315 LRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVI 356 + +C C Q TA A A +I Sbjct: 88 IVSPCIVEEVCEYCVKNDIACSQGTATPTEAFKAASLGADII 129 >UniRef50_Q5WEY2 Cluster: Putative uncharacterized protein; n=1; Bacillus clausii KSM-K16|Rep: Putative uncharacterized protein - Bacillus clausii (strain KSM-K16) Length = 698 Score = 42.7 bits (96), Expect = 0.022 Identities = 29/110 (26%), Positives = 59/110 (53%), Gaps = 8/110 (7%) Query: 122 VADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI-DFRE-GDPHLSLKEVMTPINDM 179 + +V + ++G +G+P+ G L G++T D+ R+ G + EVM+ N Sbjct: 195 IDEVWQTLLRSGHSGFPVVDET---GALAGVITRMDLAKARQFGMGEAQVTEVMSMPN-- 249 Query: 180 ITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPN 229 IT + ++ A L ++ G+LP++ ++ E + ++ RTD+ ++ YPN Sbjct: 250 ITLRANDSIDAACAHLAYNQVGRLPVVGDNNEPIGIVTRTDIVRS-LYPN 298 >UniRef50_Q3JCC7 Cluster: Peptidase M50; n=1; Nitrosococcus oceani ATCC 19707|Rep: Peptidase M50 - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 404 Score = 42.7 bits (96), Expect = 0.022 Identities = 32/113 (28%), Positives = 56/113 (49%), Gaps = 4/113 (3%) Query: 112 DPVCMGPENTVADVLEAK-KKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK 170 D V + P+ V ++E ++ +P+ +N +L G +I I R I RE ++ Sbjct: 274 DFVKVNPDMRVRTLVEEHLMRSDQRAFPVEENNRLAG-IISIPDIRKIS-REKWSQTTIG 331 Query: 171 EVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 E+MTP+ + +A +IL + +LP++ N G++ LI R DL K Sbjct: 332 ELMTPVRKVALTSPKGGAAEALFILARRNINQLPVVEN-GQIRGLIRREDLLK 383 >UniRef50_Q0SD75 Cluster: Possible nitropropane dioxygenase; n=1; Rhodococcus sp. RHA1|Rep: Possible nitropropane dioxygenase - Rhodococcus sp. (strain RHA1) Length = 266 Score = 42.7 bits (96), Expect = 0.022 Identities = 19/48 (39%), Positives = 30/48 (62%) Query: 344 VASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAP 391 + + AR +P+IA GG + ++ +LALGAS V MG+ ++EAP Sbjct: 94 IPAAARQVRIPLIASGGFATGSGLVAALALGASAVNMGTRFVASTEAP 141 >UniRef50_Q0SD94 Cluster: Possible 2-nitropropane dioxygenase; n=74; cellular organisms|Rep: Possible 2-nitropropane dioxygenase - Rhodococcus sp. (strain RHA1) Length = 334 Score = 42.7 bits (96), Expect = 0.022 Identities = 19/48 (39%), Positives = 30/48 (62%) Query: 344 VASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAP 391 + + AR +P+IA GG + ++ +LALGAS V MG+ ++EAP Sbjct: 162 IPAAARQVRIPLIASGGFATGSGLVAALALGASAVNMGTRFVASTEAP 209 >UniRef50_A4J1P0 Cluster: Putative signal-transduction protein with CBS domains; n=3; Firmicutes|Rep: Putative signal-transduction protein with CBS domains - Desulfotomaculum reducens MI-1 Length = 145 Score = 42.7 bits (96), Expect = 0.022 Identities = 28/137 (20%), Positives = 64/137 (46%), Gaps = 12/137 (8%) Query: 103 KKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR- 161 +K K ++ + P+ ++ + + ++ P+ +NG +GIVT RDI R Sbjct: 3 QKLKEIMTQNIATVSPQQSIQEATQLMSQHNVGSIPVVENGNC----VGIVTDRDIALRA 58 Query: 162 ----EGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIA 217 + +++ VMT + ++T + + +A ++ + + +LP++ N G + ++A Sbjct: 59 VSQGQNPSSTTVQSVMT--SGVVTGSPEMDVHEAANLMAERQVRRLPVVEN-GSITGMVA 115 Query: 218 RTDLKKARSYPNASKDS 234 DL Y N + + Sbjct: 116 LGDLATQNIYQNEASQA 132 >UniRef50_Q2FT94 Cluster: Putative signal-transduction protein with CBS domains; n=3; Methanomicrobiales|Rep: Putative signal-transduction protein with CBS domains - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 188 Score = 42.7 bits (96), Expect = 0.022 Identities = 26/82 (31%), Positives = 49/82 (59%), Gaps = 11/82 (13%) Query: 147 GRLIGIVTSRDI-------DFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSK 199 G +GIVT +DI D R + H+S E+MT + +IT T++DA +++ +++ Sbjct: 55 GVAVGIVTEQDINCKVVARDLRPSEVHVS--EIMT--SPLITIGTDKTVEDAAHLMIRNR 110 Query: 200 KGKLPIINNDGELVALIARTDL 221 +LPIIN+ G ++ +++ D+ Sbjct: 111 VRRLPIINDKGVVIGIVSVRDI 132 >UniRef50_Q1D9V2 Cluster: CBS domain protein; n=1; Myxococcus xanthus DK 1622|Rep: CBS domain protein - Myxococcus xanthus (strain DK 1622) Length = 138 Score = 42.3 bits (95), Expect = 0.029 Identities = 26/81 (32%), Positives = 47/81 (58%), Gaps = 7/81 (8%) Query: 146 GGRLIGIVTSRDIDFREG----DPHLS-LKEVMTPINDMITAQLGVTLQDANYILEKSKK 200 GG+L+G++T RDI R DP+ + ++EVMT +IT + TL+ A ++E+ Sbjct: 40 GGQLVGMLTDRDIAVRSAALGQDPNTTPVREVMTA--TVITCDVDATLEVAEKVMEEKMV 97 Query: 201 GKLPIINNDGELVALIARTDL 221 +L +++ + V L++ DL Sbjct: 98 RRLVVVDGERRPVGLLSLDDL 118 >UniRef50_A7HHL2 Cluster: Putative CBS domain and cyclic nucleotide-regulated nucleotidyltransferase; n=1; Anaeromyxobacter sp. Fw109-5|Rep: Putative CBS domain and cyclic nucleotide-regulated nucleotidyltransferase - Anaeromyxobacter sp. Fw109-5 Length = 641 Score = 41.9 bits (94), Expect = 0.039 Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 6/80 (7%) Query: 146 GGRLIGIVTSRDIDFR---EG-DPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKG 201 GG L+G+V+ RD+ R G D + EVMTP + + A G+ L +A ++ +S Sbjct: 211 GGALVGVVSERDLVERALANGLDAARPVSEVMTPAGEPMPA--GLALAEAMEVMVRSGVR 268 Query: 202 KLPIINNDGELVALIARTDL 221 L + + GE+V L+A DL Sbjct: 269 SLAVAGDRGEIVGLLADDDL 288 >UniRef50_A6GTG2 Cluster: Putative uncharacterized protein; n=1; Limnobacter sp. MED105|Rep: Putative uncharacterized protein - Limnobacter sp. MED105 Length = 362 Score = 41.9 bits (94), Expect = 0.039 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 7/98 (7%) Query: 295 GGNV-VTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNV 353 GG V VT + AK+ + A G+ ++ +T A T++ V + + + Sbjct: 110 GGKVIVTVVNAKHALKAEQS------GADALLVTGHEAAAHGGAVTSLVLVPAIRQVTKL 163 Query: 354 PVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAP 391 P+IA GG + G ++ +LALGA V MG+ A + E+P Sbjct: 164 PIIAAGGFGTGGGVVAALALGADGVAMGTRWAASKESP 201 Score = 35.9 bits (79), Expect = 2.6 Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 1/55 (1%) Query: 50 LTKKILLKAPLVSTPMDTVTEADMAISMALCGGIGIIH-HNCTPEYQANEVHKVK 103 +T+ ++ PLV M V AD+ + A GG+GI+ + TPE +E+ KV+ Sbjct: 5 ITEMFNIQYPLVCPGMTYVANADLVAATANAGGLGILAIGHLTPEQTLSEIRKVR 59 >UniRef50_A0TVV5 Cluster: 2-nitropropane dioxygenase, NPD; n=1; Burkholderia cenocepacia MC0-3|Rep: 2-nitropropane dioxygenase, NPD - Burkholderia cenocepacia MC0-3 Length = 330 Score = 41.9 bits (94), Expect = 0.039 Identities = 72/294 (24%), Positives = 117/294 (39%), Gaps = 40/294 (13%) Query: 184 LGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAA 243 LG + DA Y+ G + I G A R +L+ R A K L + Sbjct: 25 LGPRVSDARYVAAVVNAGGMGFIVGAGFPDADEFRDELRTCRELSGA-KRFGVNLYISRQ 83 Query: 244 IGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQ 303 G + ++++++L+ GV V + G S I P ++ G V+ ++ Sbjct: 84 AGGMERVKQQIRILIEEGV---VCVETAGASPEAI---------VPLLKEAGVKVLHKVP 131 Query: 304 AKNLIDAGVDALRVGMGSGSICITQEVMAC-GCPQATAVYQVASYARHFNVPVIADGGIQ 362 A A+R+G+ G I + E G Q ++ Q A R ++PV+ GGI Sbjct: 132 AVRYAHT---AMRMGV-DGVIVVGNECGGHPGIYQIGSIVQAAQAPREIDLPVVIGGGIG 187 Query: 363 SVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGS 422 + + LA+G V+MG+ + E + V+ K G GS E++ K S Sbjct: 188 TGRQLAGVLAMGGDAVIMGTRML----VAEELWIHPDVKAKVVEGDGS-ESVVVK----S 238 Query: 423 AMSRYFHKESDKHRVAQGVSGSIV---DKGSVL---RFLPYLQAGMQHSCQDLG 470 A+ D HRV + S V D+ V RF P++ + H G Sbjct: 239 AI-------RDHHRVLRNESAEAVLELDRAQVTEFERFRPHVMGALAHEAYVTG 285 >UniRef50_A0LL65 Cluster: Peptidase M50; n=2; Syntrophobacter fumaroxidans MPOB|Rep: Peptidase M50 - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 383 Score = 41.9 bits (94), Expect = 0.039 Identities = 35/117 (29%), Positives = 60/117 (51%), Gaps = 7/117 (5%) Query: 110 IRDPVCMGPENTVADVLEAKK-KNGFTGYPITQNGKLGGRLIGIVTSRDI-DFREGDPHL 167 +R+ + + P+ V+ ++ A + G+ GYP+ + G IGIV I D E D Sbjct: 261 VREVIGVPPDLPVSRLISAYLLRYGYKGYPVMERA---GEPIGIVEIFHIKDIHEEDRQS 317 Query: 168 -SLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 ++ EVM PIN + + + L DA + S G+L +I D ++V LI ++ L + Sbjct: 318 RTVAEVMEPINPDLVVEPDLPLIDALKKIGDSDLGRLLVI-QDKQMVGLITKSGLNR 373 >UniRef50_Q8R7I7 Cluster: Putative N-acetylmannosamine-6-phosphate 2-epimerase; n=8; Firmicutes|Rep: Putative N-acetylmannosamine-6-phosphate 2-epimerase - Thermoanaerobacter tengcongensis Length = 237 Score = 41.9 bits (94), Expect = 0.039 Identities = 33/141 (23%), Positives = 67/141 (47%), Gaps = 11/141 (7%) Query: 252 ERLKLLVNNGVDVIVLDSSQGNSTYQI---KMIKYIKETYPEIQVVGGNVVTRMQAKNLI 308 E + ++ G D++ +D+++ + + +K IKE YP+I V+ ++ T Sbjct: 85 EEVDKVIEAGADIVAIDATKAYKPGGLTTGEFLKRIKEKYPKILVMA-DIST-------Y 136 Query: 309 DAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHII 368 + G++A ++G S ++ + + AR NVP+IA+G I + + Sbjct: 137 EEGIEAEKLGFDLISTTLSGYTEYSPELEGPDYELIERLARKVNVPIIAEGRIWTPEEAV 196 Query: 369 KSLALGASTVMMGSLLAGTSE 389 K+L GA V++G+ + E Sbjct: 197 KALEKGAYAVVVGTAITRPHE 217 >UniRef50_Q3ZXE7 Cluster: Metallopeptidase, M50 family; n=3; Dehalococcoides|Rep: Metallopeptidase, M50 family - Dehalococcoides sp. (strain CBDB1) Length = 379 Score = 41.5 bits (93), Expect = 0.051 Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 4/105 (3%) Query: 118 PENTVADVL-EAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPI 176 P+NT+ L E P+ +NGKL G LI + + I + + S+++ MTP Sbjct: 259 PDNTLYQALHEYILPLNQRALPVFENGKLAG-LISLSDIKKIPTNQLN-QTSVRQAMTPF 316 Query: 177 NDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 + T L + +L+ +LP+++ +G+L+ LI+RTDL Sbjct: 317 EKLRTVGPEEHLGNVLNLLQSEDINQLPVLS-EGKLIGLISRTDL 360 >UniRef50_Q3DF47 Cluster: AcuB family protein; n=27; Streptococcus|Rep: AcuB family protein - Streptococcus agalactiae CJB111 Length = 219 Score = 41.5 bits (93), Expect = 0.051 Identities = 41/204 (20%), Positives = 91/204 (44%), Gaps = 11/204 (5%) Query: 114 VCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLI-GIVT------SRDIDFREGDPH 166 V + P+ TVA+ + +++ P+ +N +L G + G + + + E + Sbjct: 12 VYVSPDTTVAEAADLLREHHLRRLPVVENDQLVGLVTEGTMAEAQPSKATSLSIYEMNYL 71 Query: 167 LSLKEVMT-PINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKAR 225 L+ ++ I D++T +L+DA Y++ K G LP+++N G+L ++ D+ KA Sbjct: 72 LNKTKIRDIMIKDIVTVSQYASLEDAIYLMMSRKIGVLPVVDN-GQLYGIVTDRDVFKAF 130 Query: 226 SYPNASKDSNKQLLVGA--AIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKY 283 +L++ A IG RL + +++++ G +I++ Y Sbjct: 131 LEIAGYGQEGYRLVILADEGIGVLSKVLNRLSSANLSVKRLVIIERKAGKKAVEIQLEGY 190 Query: 284 IKETYPEIQVVGGNVVTRMQAKNL 307 + + ++V +V+ K + Sbjct: 191 ADKDVLKQELVFDDVIVETLEKTV 214 >UniRef50_Q24MB2 Cluster: Putative uncharacterized protein; n=2; Desulfitobacterium hafniense|Rep: Putative uncharacterized protein - Desulfitobacterium hafniense (strain Y51) Length = 214 Score = 41.5 bits (93), Expect = 0.051 Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 21/120 (17%) Query: 116 MGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPH----LSLKE 171 + PE+ +AD + ++ P+ GK L+GIVT D D RE P LS+ E Sbjct: 20 VSPEDNIADTMALMREKQINRLPVVDKGK----LVGIVT--DGDLREVSPSPATTLSIFE 73 Query: 172 V-----MTPIND-----MITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 + T I D +IT ++DA ++ + G LP++ N G+LV ++ +D+ Sbjct: 74 LNYLVGKTSIRDVAVKKVITCTPDTKIEDAALLMREHGIGALPVVEN-GKLVGIVTESDI 132 >UniRef50_Q0PQV9 Cluster: Putative inosine-5'-monophosphate dehydrogenase; n=1; Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Putative inosine-5'-monophosphate dehydrogenase - Endoriftia persephone 'Hot96_1+Hot96_2' Length = 137 Score = 41.5 bits (93), Expect = 0.051 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 9/94 (9%) Query: 410 SLEAMESKDGKGSAMSRYFHKESDKHR-VAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQD 468 SL AM K G RYF + +DK + V +G+ G + KGSV + L G++ S Sbjct: 38 SLGAMSGKQGSSD---RYFQESTDKEKLVPEGIEGRVPYKGSVTNIIYQLVGGIRSSMGY 94 Query: 469 LGARSVSVLREMSHSGDLRFMKRTYSAQLEGNVH 502 G ++ +R RF++ T + E +VH Sbjct: 95 TGCANLDEMRTKP-----RFVRVTGAGMTESHVH 123 >UniRef50_Q9YFL7 Cluster: Putative uncharacterized protein; n=1; Aeropyrum pernix|Rep: Putative uncharacterized protein - Aeropyrum pernix Length = 287 Score = 41.5 bits (93), Expect = 0.051 Identities = 36/129 (27%), Positives = 61/129 (47%), Gaps = 9/129 (6%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFRE--GDPHLS 168 RD + P++T+A + + + P+ + KL G +I I D R+ P S Sbjct: 11 RDVYTVSPDDTLAHARKLMLTHDISRLPVVEGSKLRG-IITITDIADALVRKYPSRPANS 69 Query: 169 L--KEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARS 226 + +EVM D++T + +++ A ++ K G +P++ DG L +I RTDL R Sbjct: 70 IYVREVMA--RDVVTIEGTKSVKTAASLMLKHNIGGVPVVAPDGTLEGIITRTDL--TRY 125 Query: 227 YPNASKDSN 235 Y K N Sbjct: 126 YSEKMKGVN 134 >UniRef50_Q8PYN6 Cluster: Conserved protein; n=6; Euryarchaeota|Rep: Conserved protein - Methanosarcina mazei (Methanosarcina frisia) Length = 283 Score = 41.5 bits (93), Expect = 0.051 Identities = 33/112 (29%), Positives = 57/112 (50%), Gaps = 9/112 (8%) Query: 110 IRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSL 169 +RD C + +VL+ K +G P+ ++ K ++GIVT ++ + L+L Sbjct: 12 VRDVACATLPGSRDEVLKILKNKHISGVPVLKDSK----VVGIVTRTNLLQNPEEEQLAL 67 Query: 170 KEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 +MT D IT G LQ A +L + +LP++ +DG+LV L+ D+ Sbjct: 68 --LMT--RDPITISPGSDLQSAARLLLQHGIRRLPVV-DDGKLVGLVTVADV 114 >UniRef50_Q8PUG3 Cluster: Conserved protein; n=8; Euryarchaeota|Rep: Conserved protein - Methanosarcina mazei (Methanosarcina frisia) Length = 291 Score = 41.5 bits (93), Expect = 0.051 Identities = 30/121 (24%), Positives = 57/121 (47%), Gaps = 9/121 (7%) Query: 103 KKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI--DF 160 K KH P+ + ++ + +N G P+ GK ++GI+T DI Sbjct: 171 KHVKHYMKYPPLLVNLNASIQEATRLFIRNNVHGAPVEDKGK----IVGIITYTDIAHAI 226 Query: 161 REGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTD 220 +G P++ +K++MT ++IT + L D + K G+L I+ +G +++TD Sbjct: 227 AQGKPNVKVKDIMT--KELITVDGDMQLYDVVKLFHKYNVGRL-IVTINGVPKGTLSKTD 283 Query: 221 L 221 + Sbjct: 284 V 284 >UniRef50_O27616 Cluster: Inosine-5'-monophosphate dehydrogenase related protein X; n=1; Methanothermobacter thermautotrophicus str. Delta H|Rep: Inosine-5'-monophosphate dehydrogenase related protein X - Methanobacterium thermoautotrophicum Length = 133 Score = 41.5 bits (93), Expect = 0.051 Identities = 29/116 (25%), Positives = 58/116 (50%), Gaps = 8/116 (6%) Query: 110 IRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDP-HLS 168 +RD + P++ VA + G P+ + G +L+G++T RDI G+ L Sbjct: 20 LRDVIVSHPDDLVAAANLKMVRANVGGVPVVE----GDKLVGLITHRDILLAGGEALKLR 75 Query: 169 LKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 +K++M+ D++ + + I+ + ++P++ DG LV LI ++ + KA Sbjct: 76 VKDIMS--QDLVVIDEETPISRISRIMADTGYQRIPVV-RDGRLVGLITQSCIIKA 128 >UniRef50_P54606 Cluster: Uncharacterized protein yhcV; n=6; Bacillaceae|Rep: Uncharacterized protein yhcV - Bacillus subtilis Length = 140 Score = 41.5 bits (93), Expect = 0.051 Identities = 29/110 (26%), Positives = 57/110 (51%), Gaps = 11/110 (10%) Query: 116 MGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---EG-DPHLSLKE 171 + P T+ + K++ P+ + G L G L T RDI R +G D + E Sbjct: 15 VSPNQTIQEAASLMKQHNVGAIPVVEQGVLKGML----TDRDIALRTTAQGRDGQTPVSE 70 Query: 172 VMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 VM+ ++++ ++L+DA+ ++ + + +LPI++ + LV ++A DL Sbjct: 71 VMS--TELVSGNPNMSLEDASQLMAQHQIRRLPIVDQN-NLVGIVALGDL 117 >UniRef50_Q5LSF9 Cluster: Nucleotidyltransferase/CBS/cyclic nucleotide-binding domain protein; n=15; Alphaproteobacteria|Rep: Nucleotidyltransferase/CBS/cyclic nucleotide-binding domain protein - Silicibacter pomeroyi Length = 607 Score = 41.1 bits (92), Expect = 0.068 Identities = 33/137 (24%), Positives = 59/137 (43%), Gaps = 11/137 (8%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR----EGDPH 166 RDP P+ TV + + + + ++ G L+GI+T RD+ + P Sbjct: 150 RDPATCAPDTTVQAAAQEMRARSISSLCVCED----GALVGILTQRDLSGKVVAEARSPD 205 Query: 167 LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARS 226 + +VMTP +T D + + + G +PI+ G LV ++ +TDL + ++ Sbjct: 206 TPVDQVMTPA--PLTLAPSAIGSDVLHAMMERHIGHIPIV-EAGRLVGMVTQTDLTRFQA 262 Query: 227 YPNASKDSNKQLLVGAA 243 +A S AA Sbjct: 263 VSSAELVSRLARATSAA 279 >UniRef50_Q8VKG1 Cluster: FMN-dependent alpha-hydroxy acid dehydrogenase family protein; n=27; Actinobacteria (class)|Rep: FMN-dependent alpha-hydroxy acid dehydrogenase family protein - Mycobacterium tuberculosis Length = 419 Score = 41.1 bits (92), Expect = 0.068 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 7/78 (8%) Query: 304 AKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQS 363 AK +DAGV A+ V G+ G P + S A V V+ DGGI+ Sbjct: 262 AKRAVDAGVSAISVSNHGGN-------NLDGTPASIRALPAVSAAVGDQVEVLLDGGIRR 314 Query: 364 VGHIIKSLALGASTVMMG 381 ++K++ALGA VM+G Sbjct: 315 GSDVVKAVALGARAVMIG 332 >UniRef50_Q1AXH4 Cluster: CBS domain containing membrane protein; n=1; Rubrobacter xylanophilus DSM 9941|Rep: CBS domain containing membrane protein - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 232 Score = 41.1 bits (92), Expect = 0.068 Identities = 33/132 (25%), Positives = 67/132 (50%), Gaps = 21/132 (15%) Query: 104 KYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREG 163 + + R+ V + PE +VA+ E +++ P+ + GGRL+G+V+ RD+ R+ Sbjct: 15 RVRDSMTREVVTITPEASVAEAWELCRRHRIRHLPVVE----GGRLVGLVSDRDL--RDA 68 Query: 164 DPHLS------------LKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGE 211 P S ++++M+ ++IT T++ A + + + G LP++ DG Sbjct: 69 SPPRSTGDEEHSFGWARMRDIMS--TELITIHPLDTIEHAAREIYERRIGCLPVV-EDGR 125 Query: 212 LVALIARTDLKK 223 LV +I +D+ + Sbjct: 126 LVGIITSSDMMR 137 >UniRef50_A5UX62 Cluster: Polynucleotide adenylyltransferase region; n=2; Roseiflexus|Rep: Polynucleotide adenylyltransferase region - Roseiflexus sp. RS-1 Length = 874 Score = 41.1 bits (92), Expect = 0.068 Identities = 23/61 (37%), Positives = 37/61 (60%), Gaps = 4/61 (6%) Query: 165 PHLSLKEVMT-PINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 P L+ ++MT P++ TA L T+ A +L + G LP++N+DG + LI+R DL + Sbjct: 303 PALTAADIMTRPVH---TAPLDATVAQAEELLLRYGHGALPVVNHDGVVQGLISRRDLDR 359 Query: 224 A 224 A Sbjct: 360 A 360 Score = 34.7 bits (76), Expect = 5.9 Identities = 38/153 (24%), Positives = 70/153 (45%), Gaps = 9/153 (5%) Query: 113 PVCMGP-ENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID--FREGDPHLSL 169 PV P + TVA E + G P+ + G + G+++ RD+D R G L Sbjct: 314 PVHTAPLDATVAQAEELLLRYGHGALPVVNHD---GVVQGLISRRDLDRALRHGLRDAPL 370 Query: 170 KEVMTPINDMITAQLGV-TLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYP 228 + +++ + T++ A + G+L ++++ L+ +I R+DL +A + Sbjct: 371 ARYLWHGPTLLSPDASLATVRSALAADNGDRTGRLLVVDSQKRLLGIITRSDLLRAWAAG 430 Query: 229 NASKDSNKQLLVGAAIGTRDTDRERLKLLVNNG 261 + S+ LVG A+ R DR+ L +L G Sbjct: 431 QVAGTSDHD-LVGEAL-ERFLDRDLLAILRRAG 461 >UniRef50_A3W676 Cluster: Nucleotidyltransferase/CBS/cyclic nucleotide-binding domain protein; n=4; Rhodobacteraceae|Rep: Nucleotidyltransferase/CBS/cyclic nucleotide-binding domain protein - Roseovarius sp. 217 Length = 612 Score = 41.1 bits (92), Expect = 0.068 Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 11/113 (9%) Query: 113 PVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID---FREG-DPHLS 168 P+ P+ T+ +V + + + + + G RL GI+T RD+ EG + Sbjct: 157 PITCSPDATIKEVARLMRDHVISSVVVME----GARLAGIITVRDLSNKVLAEGLGGDIR 212 Query: 169 LKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 + +VMTP D +T + G DA +L K LP+ G ++ +I +TDL Sbjct: 213 VAQVMTP--DPVTIEPGRLGLDALMLLSDLKINHLPVAQG-GRVLGMIGKTDL 262 >UniRef50_A0QGC0 Cluster: Oxidoreductase, 2-nitropropane dioxygenase family protein; n=5; Actinomycetales|Rep: Oxidoreductase, 2-nitropropane dioxygenase family protein - Mycobacterium avium (strain 104) Length = 293 Score = 41.1 bits (92), Expect = 0.068 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Query: 298 VVTRMQAKNLIDAGVDALRV-GMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVI 356 V T AK +DAGVD L V G+ G G A+ + + A H +VP++ Sbjct: 95 VGTLAAAKKAVDAGVDGLVVEGVEGGGF-----KNRFG---ASTMVLLPLVAAHVDVPIV 146 Query: 357 ADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAP 391 A GGI + + LGA V MG+ L ++++P Sbjct: 147 AAGGICDARSMAAAFVLGAEAVQMGTRLLASADSP 181 >UniRef50_A0PYB8 Cluster: CBS domain containing protein; n=3; Clostridium|Rep: CBS domain containing protein - Clostridium novyi (strain NT) Length = 431 Score = 41.1 bits (92), Expect = 0.068 Identities = 29/115 (25%), Positives = 60/115 (52%), Gaps = 8/115 (6%) Query: 110 IRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSL 169 I DP+ + ++T+ + +KN YP+ N K ++GI+T +D+ ++ D L + Sbjct: 195 ITDPIYVKFDDTIENFKNIIEKNKHQRYPVVDNNK---NVVGIITIKDLQ-KQNDNKL-V 249 Query: 170 KEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 KE+M+ ++IT T+ A +I+ P++ +L+ +++ D+ KA Sbjct: 250 KEIMS--KELITVTEKTTVAYAAHIMGWEGIELCPVVQG-RQLIGVVSTEDILKA 301 Score = 35.9 bits (79), Expect = 2.6 Identities = 17/64 (26%), Positives = 35/64 (54%) Query: 176 INDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSN 235 I D I + T+++ I+EK+K + P+++N+ +V +I DL+K + + Sbjct: 195 ITDPIYVKFDDTIENFKNIIEKNKHQRYPVVDNNKNVVGIITIKDLQKQNDNKLVKEIMS 254 Query: 236 KQLL 239 K+L+ Sbjct: 255 KELI 258 >UniRef50_A0G4J4 Cluster: 2-nitropropane dioxygenase, NPD; n=1; Burkholderia phymatum STM815|Rep: 2-nitropropane dioxygenase, NPD - Burkholderia phymatum STM815 Length = 371 Score = 41.1 bits (92), Expect = 0.068 Identities = 19/38 (50%), Positives = 26/38 (68%) Query: 353 VPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEA 390 VPV+A GG+ HI+ +LALG V +GSL GT+E+ Sbjct: 218 VPVLAAGGVTRGSHILAALALGCQGVWVGSLWLGTAES 255 >UniRef50_O86223 Cluster: Putative uncharacterized protein HI0221.1; n=1; Haemophilus influenzae|Rep: Putative uncharacterized protein HI0221.1 - Haemophilus influenzae Length = 163 Score = 41.1 bits (92), Expect = 0.068 Identities = 32/82 (39%), Positives = 43/82 (52%), Gaps = 8/82 (9%) Query: 399 GVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHR-VAQGVSGSIVDKGSVLRFLPY 457 G K YRGMGSL AM KGS+ RYF ++ + V +G+ G I KG L+ + + Sbjct: 55 GRAFKSYRGMGSLGAM----AKGSS-DRYFQSDNAADKLVPEGIEGRIPYKG-YLKEIIH 108 Query: 458 LQAGMQHSCQDL-GARSVSVLR 478 Q G SC L G ++ LR Sbjct: 109 QQMGGLRSCMGLTGCATIDELR 130 >UniRef50_Q3ZYM9 Cluster: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; n=4; Chloroflexi|Rep: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase - Dehalococcoides sp. (strain CBDB1) Length = 244 Score = 41.1 bits (92), Expect = 0.068 Identities = 37/159 (23%), Positives = 63/159 (39%), Gaps = 9/159 (5%) Query: 232 KDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMI--KYIKETYP 289 K+ L+ +G E +K L+ GVD ++L ++ + +K I +Y Sbjct: 74 KEIANSALIPVEVGGGIRSMETVKKLLVAGVDRVILGTAAVENPELVKEICARYADSVAV 133 Query: 290 EIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQ----EVMACGCPQATAVYQVA 345 I G V TR N +DAL + + I + ++ G + Sbjct: 134 SIDARNGKVATRGWVTN---TEIDALELARSMKKLGIRRFIYTDISRDGTLSEPNFAAIR 190 Query: 346 SYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLL 384 NVPVIA GG+ S+ H+ +GA ++G + Sbjct: 191 DLISAINVPVIASGGVSSLSHLRLLKDIGAEGAIVGKAI 229 >UniRef50_Q98QF8 Cluster: MG2+ TRANSPORT PROTEIN; n=1; Mycoplasma pulmonis|Rep: MG2+ TRANSPORT PROTEIN - Mycoplasma pulmonis Length = 485 Score = 40.7 bits (91), Expect = 0.090 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%) Query: 148 RLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIIN 207 +L+G V DI F DP+ +K VM +N ++T TL+ A I K LP+IN Sbjct: 173 KLLGSVALEDIIFE--DPYEKIKNVMFSVNSILTTD---TLEHAALIFSKEGMSVLPVIN 227 Query: 208 NDGELVALIARTDL 221 + L+ ++ ++ Sbjct: 228 QNKYLIGMVTTDEI 241 >UniRef50_Q74HC1 Cluster: Glycolate oxidase; n=8; Lactobacillaceae|Rep: Glycolate oxidase - Lactobacillus johnsonii Length = 412 Score = 40.7 bits (91), Expect = 0.090 Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 11/104 (10%) Query: 281 IKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATA 340 I+ IKE ++ V+ V A I AG D + V G +EV G P Sbjct: 227 IRKIKEI-ADVPVIVKGVECAEDAMLAIGAGADGIVVSNHGG-----REVD--GAPATID 278 Query: 341 VY-QVASYARHFN--VPVIADGGIQSVGHIIKSLALGASTVMMG 381 V ++A R N VP+I DGG++ H+ K+LALGA V +G Sbjct: 279 VLPEIAKAVRSSNHRVPIILDGGVRRGSHVFKALALGADLVGIG 322 >UniRef50_Q9LUF7 Cluster: Emb|CAB86899.1; n=6; Magnoliophyta|Rep: Emb|CAB86899.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 548 Score = 40.7 bits (91), Expect = 0.090 Identities = 24/74 (32%), Positives = 45/74 (60%), Gaps = 7/74 (9%) Query: 148 RLIGIVTSRDIDFREGDPHL-----SLKEVMTPINDMITAQLGVTLQDANYILEKSKKGK 202 +L+GI+TS+DI R +L ++++VMTP + T + + +A +I+ K Sbjct: 271 KLVGILTSKDILMRVISQNLPQETTTVEKVMTPNPESATVDMAIV--EALHIMHNGKFLH 328 Query: 203 LPIINNDGELVALI 216 LP+++ DG++VA+I Sbjct: 329 LPVLDKDGDVVAVI 342 >UniRef50_Q3IUS4 Cluster: Probable metalloprotease/ CBS domain protein; n=1; Natronomonas pharaonis DSM 2160|Rep: Probable metalloprotease/ CBS domain protein - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 396 Score = 40.7 bits (91), Expect = 0.090 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 4/104 (3%) Query: 121 TVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMI 180 T+ +L+ + TGYP+ + GG+L+GIVT DI + + D+ Sbjct: 279 TLDAILDRMFEERHTGYPVVE----GGKLVGIVTLADIRNVHPEKRSETRVADVMSEDLE 334 Query: 181 TAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 DA L + G+L + + G L L+ R+DL A Sbjct: 335 AVSPDTEAMDAMRQLAQHSVGRLVVTDEFGNLAGLLTRSDLVTA 378 >UniRef50_A2BJY0 Cluster: Voltage-gated chloride channel protein; n=1; Hyperthermus butylicus DSM 5456|Rep: Voltage-gated chloride channel protein - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 563 Score = 40.7 bits (91), Expect = 0.090 Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 10/118 (8%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI-DFREGD-PHLS 168 R V + P++ + V+E + TG+P+ + GR++G++T D+ +R + + Sbjct: 444 RSVVVVRPDDPLKRVIELTAETHHTGFPVV----VDGRVVGMITLSDVLRYRHSELGKVK 499 Query: 169 LKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINN--DGELVALIARTDLKKA 224 +KE MT +I +L DA + + G+LP++ N +L+ +I + D+ +A Sbjct: 500 VKEAMT--RSVIAVLPDDSLADALRKMLRYGIGRLPVVENYESMKLIGIITKKDIVRA 555 >UniRef50_Q58069 Cluster: Uncharacterized protein MJ0653; n=1; Methanocaldococcus jannaschii|Rep: Uncharacterized protein MJ0653 - Methanococcus jannaschii Length = 194 Score = 40.7 bits (91), Expect = 0.090 Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 9/113 (7%) Query: 113 PVCMGPEN-TVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKE 171 PV +N ++ D+ +N I +N K IGIVT RDI R +L K+ Sbjct: 16 PVIKATKNMSIYDIANIMTENNIGAVVIVENNKP----IGIVTERDIVKRVVSKNLKPKD 71 Query: 172 VMTP---INDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 V+ +IT ++ +A I+ +LP++ DGELV ++ ++D+ Sbjct: 72 VLAEEVMSKKIITIPQNASITEAAKIMATHGIKRLPVV-KDGELVGIVTQSDI 123 >UniRef50_Q9RVN7 Cluster: Acetoin utilization protein, putative; n=4; Deinococci|Rep: Acetoin utilization protein, putative - Deinococcus radiodurans Length = 209 Score = 40.3 bits (90), Expect = 0.12 Identities = 40/186 (21%), Positives = 84/186 (45%), Gaps = 22/186 (11%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI------------ 158 R PV + P+ V D L+ + P+ ++GK L+GI T +D+ Sbjct: 9 RTPVTVTPDTPVMDALKLISERRVRRLPVLRDGK----LVGITTRKDLKDAMPSKATTLS 64 Query: 159 --DFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALI 216 + L+++E+M +ITAQ ++DA +++ K G LP++N G++ +I Sbjct: 65 VWELNYLLSKLTVEEIMG--RPVITAQEDEYMEDAALRMQEHKFGGLPVLNAQGQMSDII 122 Query: 217 ARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIV--LDSSQGNS 274 +D+ +A + + ++L + +R + +N + V +D + GN Sbjct: 123 TTSDVIRAFTTILGMNEGGQRLTLDMPDVPGSLERAAQAVQPSNIISVATYDVDGAGGNR 182 Query: 275 TYQIKM 280 + +++ Sbjct: 183 RFVLRV 188 >UniRef50_A4AAP3 Cluster: Acetoin utilization protein AcuB; n=1; Congregibacter litoralis KT71|Rep: Acetoin utilization protein AcuB - Congregibacter litoralis KT71 Length = 147 Score = 40.3 bits (90), Expect = 0.12 Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 15/119 (12%) Query: 113 PVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI----DFR--EGDPH 166 P +GP++++ D +++ PI N G +IG+V+ RD+ D R D Sbjct: 12 PYTLGPDDSLLDAASLMREHHIRHVPIVAN---DGNVIGVVSHRDVLAASDSRLVHQDLQ 68 Query: 167 LSLKEVMTPINDMITAQLGVTLQDANY-----ILEKSKKGKLPIINNDGELVALIARTD 220 S KE ++ ++T+ + +DA L K + G +P + DG LV +I+ +D Sbjct: 69 SSAKENYVALSAVMTSPVQTVTEDAELRAVAGYLRKQRLGCMP-VTRDGALVGIISDSD 126 >UniRef50_A3SFF5 Cluster: FMN-dependent alpha-hydroxy acid dehydrogenase; n=2; Sulfitobacter|Rep: FMN-dependent alpha-hydroxy acid dehydrogenase - Sulfitobacter sp. EE-36 Length = 375 Score = 40.3 bits (90), Expect = 0.12 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 7/78 (8%) Query: 304 AKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQS 363 A+ +DAGV + V G + T + Q AV Q +VPV DGGI+ Sbjct: 246 ARRFVDAGVAGIIVSNHGGRVLDT---VPAPVTQLAAVVQAVGQ----DVPVYLDGGIRR 298 Query: 364 VGHIIKSLALGASTVMMG 381 + K+LALGA V++G Sbjct: 299 GSDVFKALALGAEAVLVG 316 >UniRef50_Q3SB86 Cluster: CBS domain protein; n=1; uncultured euryarchaeote Alv-FOS5|Rep: CBS domain protein - uncultured euryarchaeote Alv-FOS5 Length = 156 Score = 40.3 bits (90), Expect = 0.12 Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 5/95 (5%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK 170 +D V + +A V++ KK +G P+ N G+LIG+VT DI P Sbjct: 10 KDVVYVHDNEGIAKVIDIMKKRKISGLPVVNNS---GKLIGVVTDGDIIRSLDIPDFPTS 66 Query: 171 EVMTPINDMITAQLGVTLQ--DANYILEKSKKGKL 203 V P D I + V ++ D LE K GK+ Sbjct: 67 AVSPPPFDFIERLIKVKMEEWDVERALEMWKSGKV 101 Score = 34.3 bits (75), Expect = 7.8 Identities = 17/56 (30%), Positives = 33/56 (58%), Gaps = 2/56 (3%) Query: 169 LKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 + +VMT D + + ++ A I+ + +LP++++DG+LV ++ R DL KA Sbjct: 101 VSDVMT--KDPASVHMNDDVEKAADIMLEKNVHRLPVVDDDGKLVGIVTRLDLLKA 154 >UniRef50_A7IAI3 Cluster: Putative signal transduction protein with CBS domains; n=1; Candidatus Methanoregula boonei 6A8|Rep: Putative signal transduction protein with CBS domains - Methanoregula boonei (strain 6A8) Length = 249 Score = 40.3 bits (90), Expect = 0.12 Identities = 29/110 (26%), Positives = 56/110 (50%), Gaps = 12/110 (10%) Query: 118 PENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTP-- 175 P +T+ V + GFT +P+ + RL+G+++ RD+ R G ++ + T Sbjct: 141 PADTLQQVYAKITECGFTAFPVVKKR----RLVGLISRRDL-IRSGGVRSAIAQNSTRTV 195 Query: 176 ----INDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 I D+IT G L +A ++ + +LP+++N+ +V +I R D+ Sbjct: 196 GDVMIPDVITVPSGSLLSEAARLMVDNDISRLPVVDNE-SVVGIIDRHDV 244 >UniRef50_Q15XE0 Cluster: 2-nitropropane dioxygenase, NPD; n=9; Proteobacteria|Rep: 2-nitropropane dioxygenase, NPD - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 319 Score = 39.9 bits (89), Expect = 0.16 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 7/88 (7%) Query: 304 AKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQS 363 A ++AGVD L V G G + +++ + NVP++A GGI Sbjct: 128 ALKAVEAGVDGLIVEGGEGGGFKNAD-------DVSSMVLIPQVCEAVNVPIVAAGGIMD 180 Query: 364 VGHIIKSLALGASTVMMGSLLAGTSEAP 391 + ++ALGA V+MG+ + +E+P Sbjct: 181 GRSMAAAMALGAEGVLMGTRILSATESP 208 >UniRef50_A6GD90 Cluster: Acetoin utilization protein AcuB; n=1; Plesiocystis pacifica SIR-1|Rep: Acetoin utilization protein AcuB - Plesiocystis pacifica SIR-1 Length = 141 Score = 39.9 bits (89), Expect = 0.16 Identities = 23/59 (38%), Positives = 37/59 (62%), Gaps = 3/59 (5%) Query: 167 LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKAR 225 +SL VMT D+ITA T+++A +LE S LP++ NDG L+ +++ DL++ R Sbjct: 1 MSLDAVMT--TDLITAPPTATVREALRLLEDSDIRHLPVV-NDGHLIGIVSDRDLREYR 56 >UniRef50_A6CN21 Cluster: CBS domain protein; n=1; Bacillus sp. SG-1|Rep: CBS domain protein - Bacillus sp. SG-1 Length = 144 Score = 39.9 bits (89), Expect = 0.16 Identities = 29/106 (27%), Positives = 57/106 (53%), Gaps = 11/106 (10%) Query: 120 NTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---EGDPHLS-LKEVMTP 175 + V +V K+N G PI G L+G++T RDI R E P S ++EVM+ Sbjct: 18 DNVYEVAVKMKENDVGGIPIVD----GDHLVGMITDRDIVVRGVAEKHPGSSKVEEVMS- 72 Query: 176 INDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 ++++T T+ +A ++ + + +LP+++ +L+ +++ DL Sbjct: 73 -DELVTVGADTTIDEAASLMSRHQIRRLPVVDGQ-KLIGIVSLGDL 116 >UniRef50_Q01N18 Cluster: OSIGBa0147B06.5 protein; n=3; Oryza sativa|Rep: OSIGBa0147B06.5 protein - Oryza sativa (Rice) Length = 224 Score = 39.9 bits (89), Expect = 0.16 Identities = 22/78 (28%), Positives = 43/78 (55%), Gaps = 2/78 (2%) Query: 147 GRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPII 206 GR IG+V+ +D ++ EVM+ + IT T+ +A ++ K K ++P++ Sbjct: 143 GRCIGVVSKKDKAKASNGLDSTVGEVMS--SPAITLTPEKTVLEAAALMLKEKVHRIPVV 200 Query: 207 NNDGELVALIARTDLKKA 224 N +++ ++ RTD+ KA Sbjct: 201 NEQQQVIGIVTRTDVFKA 218 >UniRef50_A7DSJ1 Cluster: Putative signal-transduction protein with CBS domains; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Putative signal-transduction protein with CBS domains - Candidatus Nitrosopumilus maritimus SCM1 Length = 165 Score = 39.9 bits (89), Expect = 0.16 Identities = 29/87 (33%), Positives = 47/87 (54%), Gaps = 7/87 (8%) Query: 150 IGIVTSRD----IDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPI 205 +GIVT RD I PH + EVM+ + +IT + T+ +A I+++ KLP+ Sbjct: 67 LGIVTERDFVTKIVAERKTPHTKIFEVMS--SPLITIKSESTIWEAAEIMKEKSIHKLPV 124 Query: 206 INNDGELVALIARTDLKKARSYPNASK 232 I D E+V +I TD+ + S + S+ Sbjct: 125 I-EDEEIVGIITTTDIVRISSVGSDSQ 150 >UniRef50_Q9CG58 Cluster: L-lactate oxidase; n=6; Bacteria|Rep: L-lactate oxidase - Lactococcus lactis subsp. lactis (Streptococcus lactis) Length = 383 Score = 39.5 bits (88), Expect = 0.21 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 11/121 (9%) Query: 261 GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMG 320 G+ I + QG I+ IK I + V+ V + + A + I+AG D + V Sbjct: 226 GISEIYAAAKQGLVLEDIQKIKKITN----LPVIVKGVQSPIDADDAINAGADGIWVSNH 281 Query: 321 SGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMM 380 G G P + V + + + + VP++ D G++ H+ K+LA GA V + Sbjct: 282 GGR-------QLDGGPASIDVLPLIAKSVNHRVPIVFDSGVRRGEHVFKALAQGADVVAV 334 Query: 381 G 381 G Sbjct: 335 G 335 >UniRef50_Q62DY2 Cluster: FMN-dependent dehydrogenase; n=17; Proteobacteria|Rep: FMN-dependent dehydrogenase - Burkholderia mallei (Pseudomonas mallei) Length = 412 Score = 39.5 bits (88), Expect = 0.21 Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 8/134 (5%) Query: 281 IKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATA 340 +K+++ +P V+ G ++ A+ +D GVD + + G P Sbjct: 243 VKWLRARWPGRIVIKG-ILDPDDARRAVDEGVDGILISNHGGR-------QLDPAPSVMD 294 Query: 341 VYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGV 400 V + A ++ DGG++ +IK+LALGAS V +G A GE S + Sbjct: 295 VLPEIAEAVGKRTEILMDGGVRRGADVIKALALGASAVSIGRAYVYGLGAAGEKGVSRCL 354 Query: 401 RLKKYRGMGSLEAM 414 L K + +L M Sbjct: 355 ELLKGEMLPALNMM 368 >UniRef50_Q2CIM8 Cluster: Alcohol dehydrogenase, zinc containing; n=2; Rhodobacterales|Rep: Alcohol dehydrogenase, zinc containing - Oceanicola granulosus HTCC2516 Length = 329 Score = 39.5 bits (88), Expect = 0.21 Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 8/156 (5%) Query: 295 GGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVP 354 GG + ++ + G + + + + ++ +M G P+ ++ RH V Sbjct: 17 GGPEALKPVSRTMPAPGPKDVLIRVRASAVSRADGMMRAGTPRFARLFLGLRRPRHDLVG 76 Query: 355 VIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAM 414 G + SVGH + + A G M L G + A DGV L K M EA Sbjct: 77 TCFSGEVVSVGHAVSNFAAGDPVYGMSGLNFG-ANASHICMDEDGVLLHKPAAMSHEEAA 135 Query: 415 ESKDGKGSAMSRYFHKESDKHRVAQ-----GVSGSI 445 DG ++++ F KE + R Q G SGS+ Sbjct: 136 VMSDGAVTSLN--FLKEIGELRAGQRILILGASGSL 169 >UniRef50_Q1AXT4 Cluster: Inorganic diphosphatase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Inorganic diphosphatase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 540 Score = 39.5 bits (88), Expect = 0.21 Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 4/80 (5%) Query: 167 LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARS 226 L +K+VM +++TA L + K+ G++PI+++DG L +I DL AR Sbjct: 68 LRVKDVMN--KNLVTANRNDPLHSVGLAMAKNNIGQIPIVDDDGTLAGIITERDL--ARM 123 Query: 227 YPNASKDSNKQLLVGAAIGT 246 Y S+D + ++G+ Sbjct: 124 YIRESRDPSTFAHTPVSVGS 143 >UniRef50_A5URS2 Cluster: CBS domain containing protein; n=2; Roseiflexus|Rep: CBS domain containing protein - Roseiflexus sp. RS-1 Length = 225 Score = 39.5 bits (88), Expect = 0.21 Identities = 29/117 (24%), Positives = 58/117 (49%), Gaps = 11/117 (9%) Query: 114 VCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLI--GIVTSRDID-------FREGD 164 + + P T+A+ ++ PI +NGKL G + + +++ +D +R Sbjct: 15 IVIAPTATLAEAQRLMEQRRIRRLPIVENGKLAGIITRGDLRSAQPVDTTLSYYEWRALL 74 Query: 165 PHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 +++ E MT +IT + DA ++ K K G LP+++++G +V +I +DL Sbjct: 75 DRVTVAECMT--RHVITITPDASTLDAARLMLKHKIGGLPVVDDEGRVVGIITESDL 129 >UniRef50_Q4PDX7 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 708 Score = 39.5 bits (88), Expect = 0.21 Identities = 33/101 (32%), Positives = 51/101 (50%), Gaps = 8/101 (7%) Query: 121 TVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---EG-DPHL-SLKEVMTP 175 T V+E+ TG I G + G++ GI TS+D+ R G DP S+ VMTP Sbjct: 265 TAVCVMESTGSGPGTGQ-IGGGGAVSGKIAGIFTSKDVVLRVIAAGLDPKTCSVVRVMTP 323 Query: 176 INDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALI 216 D TA +T+Q+A + + LP+++ D LV ++ Sbjct: 324 HPD--TAPPSLTIQEALRKMHDGRYLNLPVVDVDSRLVGVV 362 >UniRef50_Q8TZ50 Cluster: CBS-domain-containing protein; n=1; Methanopyrus kandleri|Rep: CBS-domain-containing protein - Methanopyrus kandleri Length = 393 Score = 39.5 bits (88), Expect = 0.21 Identities = 30/114 (26%), Positives = 55/114 (48%), Gaps = 12/114 (10%) Query: 113 PVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI-DF-REGDP--HLS 168 P + P+ + + + +G P+ ++G+ +G+VT DI D RE D + Sbjct: 79 PETVTPDTLIVEAITEMIDSGLRALPVVEDGEF----VGLVTEYDIIDVARESDELTKID 134 Query: 169 LKEVM-TPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 +EVM TP+ IT T+ A I+ +LP++N+ +L ++ TD+ Sbjct: 135 AREVMSTPV---ITIHENDTIAKARAIMRDHGISRLPVVNDANKLRGIVTTTDI 185 Score = 35.5 bits (78), Expect = 3.4 Identities = 19/56 (33%), Positives = 35/56 (62%), Gaps = 1/56 (1%) Query: 169 LKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 ++E+MTP ++ITA+ G L LE+ ++PI+ +DG++V +I+ D+ A Sbjct: 8 VEEIMTPAEEVITAEPGEPLSKIFSKLERHGVKEIPIV-DDGKVVGMISYYDVVDA 62 >UniRef50_O13965 Cluster: Meiotically up-regulated gene 70 protein; n=2; Schizosaccharomyces pombe|Rep: Meiotically up-regulated gene 70 protein - Schizosaccharomyces pombe (Fission yeast) Length = 730 Score = 39.5 bits (88), Expect = 0.21 Identities = 38/160 (23%), Positives = 71/160 (44%), Gaps = 12/160 (7%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---EG-DPH- 166 +P +G TVA+ E+ ++G + + NG + G+ T+ D+ R G DP+ Sbjct: 266 EPFLVGTRTTVAEATESMARSGVSAVLVMDNGAVS----GVFTAHDVVLRVLAAGLDPYR 321 Query: 167 LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA-R 225 S+ VMTP D A L V+ I + K LP+++ ++ +++ L A Sbjct: 322 SSVIRVMTPHPDCALASLRVSTALERMI--EGKFSNLPVVDESDAIIGMLSLFHLATAIE 379 Query: 226 SYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVI 265 P ++ Q A I + ++ + L+ N +V+ Sbjct: 380 QTPEEEEEVFDQAENDAGIEPSNGFEDQQQQLLGNSNEVV 419 >UniRef50_Q7U851 Cluster: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; n=39; Bacteria|Rep: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase - Synechococcus sp. (strain WH8102) Length = 255 Score = 39.5 bits (88), Expect = 0.21 Identities = 40/142 (28%), Positives = 64/142 (45%), Gaps = 12/142 (8%) Query: 252 ERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVG-----GNVVTRMQAKN 306 ER + L+ G+D ++L + + Q +++ + E YP VVG G V TR + Sbjct: 87 ERAEQLLACGLDRVILGTV---AIEQPDLVRSLAERYPGRIVVGIDAKDGRVATRGWIEQ 143 Query: 307 LIDAGVDALRVGMGSG-SICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVG 365 D R SG + IT ++ G + + + A +VPVIA GGI + Sbjct: 144 SDVLATDLARTFSSSGIAAIITTDIATDGTLAGPNLEALRTMAASSSVPVIASGGIGCMA 203 Query: 366 HIIKSL---ALGASTVMMGSLL 384 ++ L LG S V++G L Sbjct: 204 DLLSLLPLEPLGVSGVIVGRAL 225 >UniRef50_Q4US80 Cluster: 2-nitropropane dioxygenase; n=9; Proteobacteria|Rep: 2-nitropropane dioxygenase - Xanthomonas campestris pv. campestris (strain 8004) Length = 364 Score = 39.1 bits (87), Expect = 0.27 Identities = 22/47 (46%), Positives = 27/47 (57%), Gaps = 2/47 (4%) Query: 350 HFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEA--PGEY 394 H +PVIA GGI I +L LGAS V +G+ L T EA PG + Sbjct: 217 HLEIPVIAAGGIADARGIAAALTLGASAVQIGTGLLRTPEAALPGAW 263 >UniRef50_Q180W2 Cluster: Putative uncharacterized protein; n=1; Clostridium difficile 630|Rep: Putative uncharacterized protein - Clostridium difficile (strain 630) Length = 153 Score = 39.1 bits (87), Expect = 0.27 Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Query: 170 KEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPN 229 KE+MT D+I A+ ++ D +L K G LP+++++ +V +I+ TD+ K Y Sbjct: 7 KEIMT--TDVIVAKQDDSIADVANMLIAEKIGGLPVVDSENRVVGIISETDILKKEKYIE 64 Query: 230 A 230 A Sbjct: 65 A 65 >UniRef50_A6QB31 Cluster: 2-nitropropane dioxygenase; n=29; Bacteria|Rep: 2-nitropropane dioxygenase - Sulfurovum sp. (strain NBC37-1) Length = 369 Score = 39.1 bits (87), Expect = 0.27 Identities = 18/38 (47%), Positives = 24/38 (63%) Query: 352 NVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSE 389 ++PVIA GG+ I+K + LGAS V MG+ GT E Sbjct: 215 DIPVIAAGGVWDRADIVKMMELGASAVQMGTRFIGTVE 252 >UniRef50_A3PVW7 Cluster: 2-nitropropane dioxygenase, NPD; n=8; Corynebacterineae|Rep: 2-nitropropane dioxygenase, NPD - Mycobacterium sp. (strain JLS) Length = 295 Score = 39.1 bits (87), Expect = 0.27 Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 8/93 (8%) Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357 V T A+ +DAG+D L V G+ E G P+ + + F+VPV+A Sbjct: 120 VGTAAAARRAVDAGIDVL-VARGA-------EGGGHGEPRVGTLALLTDLLERFDVPVLA 171 Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEA 390 GGI S + LA GAS +G+ A EA Sbjct: 172 AGGIASGRGLAAVLAAGASAAWIGTGFAACPEA 204 >UniRef50_A1ZUR2 Cluster: CBS domain protein; n=2; Bacteroidetes|Rep: CBS domain protein - Microscilla marina ATCC 23134 Length = 140 Score = 39.1 bits (87), Expect = 0.27 Identities = 22/57 (38%), Positives = 37/57 (64%), Gaps = 3/57 (5%) Query: 167 LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 L++++VM I+ ++T T+++A IL K + LP+I+N+G LV +I TDL K Sbjct: 80 LTIEQVM--IDQLVTVNTETTIREAAEILSKKEFHALPVIDNNG-LVGIITTTDLIK 133 >UniRef50_Q54H97 Cluster: Putative acetoin dehydrogenase; n=1; Dictyostelium discoideum AX4|Rep: Putative acetoin dehydrogenase - Dictyostelium discoideum AX4 Length = 145 Score = 39.1 bits (87), Expect = 0.27 Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 16/115 (13%) Query: 120 NTVADV-LEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLS------LKEV 172 +T DV L++ N P+ N G L GI+T RD+ P L L+++ Sbjct: 19 DTTLDVALKSLNANSIHRLPVVDND---GNLKGIITDRDLRLATDSPFLPENNEDRLEKL 75 Query: 173 MTPINDMITAQLGVTLQDANYILEKSKK------GKLPIINNDGELVALIARTDL 221 I Q VT++D + ++E +K G LP+++ G L+ ++ R+DL Sbjct: 76 RLHKVSSIMKQNPVTIEDFSPVVEAAKLMRVTNVGGLPVLDKKGRLIGMVTRSDL 130 Score = 34.7 bits (76), Expect = 5.9 Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%) Query: 169 LKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYP 228 +K++M+ + T L TL A L + +LP+++NDG L +I DL+ A P Sbjct: 5 VKQLMS--KSLFTINLDTTLDVALKSLNANSIHRLPVVDNDGNLKGIITDRDLRLATDSP 62 Query: 229 NASKDSNKQL 238 +++ +L Sbjct: 63 FLPENNEDRL 72 >UniRef50_Q2RGX5 Cluster: Ferredoxin-dependent glutamate synthase; n=1; Moorella thermoacetica ATCC 39073|Rep: Ferredoxin-dependent glutamate synthase - Moorella thermoacetica (strain ATCC 39073) Length = 472 Score = 38.7 bits (86), Expect = 0.36 Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 10/85 (11%) Query: 307 LIDAGVDALRV-GMGS---GSICITQEVMACGCPQATAVYQVASYARHFNVP----VIAD 358 L++AGVD + + G G+ GS I Q+ G P AV + A++ + V +IA Sbjct: 292 LLEAGVDFIAIDGAGAASKGSPPIVQDDF--GVPTVYAVNRAATFLKKQGVKDRVSLIAG 349 Query: 359 GGIQSVGHIIKSLALGASTVMMGSL 383 GG+ + G +K LALGA V +G++ Sbjct: 350 GGLVTPGDFLKILALGADAVYIGTI 374 >UniRef50_Q08PS9 Cluster: CBS; n=1; Stigmatella aurantiaca DW4/3-1|Rep: CBS - Stigmatella aurantiaca DW4/3-1 Length = 142 Score = 38.7 bits (86), Expect = 0.36 Identities = 32/136 (23%), Positives = 67/136 (49%), Gaps = 13/136 (9%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK 170 RD + P+ T+ D + ++ GF P+ K+ IG++T RDI F+ L + Sbjct: 9 RDVTSIRPDQTLTDAAKHMRQQGFGLLPVCHVQKM----IGLLTDRDIVFQAIAERLDPQ 64 Query: 171 EVMTPINDMIT------AQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 + TP++D+++ A L A ++ + +LP+++ LV +++ D+ + Sbjct: 65 Q--TPVSDILSEGPPRYAFEDDELATAARLMTEHGLPRLPVLDRHQNLVGMVSLKDVSRE 122 Query: 225 R-SYPNASKDSNKQLL 239 + P+ + S ++LL Sbjct: 123 EPAMPSRTDTSLEELL 138 >UniRef50_A3M1P1 Cluster: Magnesium and cobalt efflux protein; n=1; Acinetobacter baumannii ATCC 17978|Rep: Magnesium and cobalt efflux protein - Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) Length = 234 Score = 38.7 bits (86), Expect = 0.36 Identities = 27/130 (20%), Positives = 56/130 (43%), Gaps = 2/130 (1%) Query: 165 PHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINND--GELVALIARTDLK 222 P ++EVMTP MI+ Q L D ++L +S + P+ + D +V ++ DL Sbjct: 9 PATKIREVMTPRTAMISMQEDDQLLDILHVLVESAHSRFPVFSADQPDNVVGILLAKDLL 68 Query: 223 KARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIK 282 + PN D + + + L++L + + ++ G++ + + Sbjct: 69 PFLTEPNTKLDIGSLMRQPLFVPESARSDQVLRMLKHTQTHIAIVIDEYGSTAGLVTLED 128 Query: 283 YIKETYPEIQ 292 ++E EI+ Sbjct: 129 ILEEIVGEIE 138 >UniRef50_A0HCZ3 Cluster: FMN-dependent alpha-hydroxy acid dehydrogenase; n=1; Comamonas testosteroni KF-1|Rep: FMN-dependent alpha-hydroxy acid dehydrogenase - Comamonas testosteroni KF-1 Length = 380 Score = 38.7 bits (86), Expect = 0.36 Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Query: 305 KNLIDAGVDALRVGMGSGSICITQEV--MACGCPQATAVYQVASYARHFNVPVIADGGIQ 362 K L+ A A V +G+ +I ++ + A V A ++P++ DGG++ Sbjct: 253 KGLLSARAAAKAVELGADAIVVSNHGGRVLDSAVSALEVLPAIREATPAHIPLLMDGGVR 312 Query: 363 SVGHIIKSLALGASTVMMG 381 ++K++ALGAS V++G Sbjct: 313 QGTDVLKAIALGASAVLLG 331 >UniRef50_Q97U50 Cluster: Putative uncharacterized protein; n=1; Sulfolobus solfataricus|Rep: Putative uncharacterized protein - Sulfolobus solfataricus Length = 131 Score = 38.7 bits (86), Expect = 0.36 Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 6/116 (5%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK 170 R+P+ + PE ++ D + K+ I + IGIVT RDI R ++L Sbjct: 9 RNPLTVKPETSIRDAAKIMKRENLGSLIIVDETN---KPIGIVTERDI-LRAVADEVALD 64 Query: 171 EVMTPI--NDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 ++ I +IT + +A I+ ++ L ++ GELV +I+ D KA Sbjct: 65 SPVSTIMTRGLITIPPNKDVTEALIIMYQNNVRHLAVVGQSGELVGVISIRDAAKA 120 >UniRef50_Q8TXY3 Cluster: CBS domain-containing protein; n=1; Methanopyrus kandleri|Rep: CBS domain-containing protein - Methanopyrus kandleri Length = 278 Score = 38.7 bits (86), Expect = 0.36 Identities = 32/125 (25%), Positives = 58/125 (46%), Gaps = 17/125 (13%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR------EGDP 165 DP + + TV + E F P+ +N GRL G+VT+ D+ E P Sbjct: 154 DPETVPSDITVLEAAEIMVDREFRRLPVVEN----GRLCGLVTATDVLHHVSSMATETSP 209 Query: 166 HLSLKEVM-TPI-----NDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIART 219 S++EVM P+ D+IT + V +++A ++ + G L ++ +++ +I Sbjct: 210 DASVEEVMDVPVEEIMTEDVITIEPDVNIEEAALTMKGANVGSL-VVTEGNDVIGIITER 268 Query: 220 DLKKA 224 D+ A Sbjct: 269 DIMYA 273 Score = 35.5 bits (78), Expect = 3.4 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 18/123 (14%) Query: 114 VCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI-DFREGDPH------ 166 V M P TV ++ + GF P+T+ G+L L+GI+T +D+ D+ G+ Sbjct: 15 VSMPPTATVKSAVDTMIRYGFRRIPVTEPGEL--ELVGIMTGKDVLDYLVGERRKIIERR 72 Query: 167 ---LSLKEVMTPINDMITAQLGV-----TLQDANYILEKSKKGKLPIINNDGELVALIAR 218 L + P+ ++ ++ V T++ A + + + G LPI+ D +LV +I Sbjct: 73 YGSTFLPALHEPVRSLMRTEVYVITPYDTVRKAVRTMFEFEVGALPIV-KDKKLVGIITE 131 Query: 219 TDL 221 D+ Sbjct: 132 RDI 134 >UniRef50_O26296 Cluster: Glutamate synthase (NADPH), alpha subunit; n=2; Methanobacteriaceae|Rep: Glutamate synthase (NADPH), alpha subunit - Methanobacterium thermoautotrophicum Length = 499 Score = 38.7 bits (86), Expect = 0.36 Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 7/75 (9%) Query: 312 VDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFN----VPVIADGGIQSVGHI 367 VD ++ G G+G +T+ G P A+ + + N V +IA GGI+S + Sbjct: 330 VDGMQGGTGAGPDVVTEH---SGIPTIAAIVEADEALKEVNLRDEVSLIAAGGIRSGADV 386 Query: 368 IKSLALGASTVMMGS 382 K++ALGA V +G+ Sbjct: 387 AKAIALGADAVYIGT 401 >UniRef50_A5UM30 Cluster: IMP dehydrogenase related protein; n=1; Methanobrevibacter smithii ATCC 35061|Rep: IMP dehydrogenase related protein - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 272 Score = 38.7 bits (86), Expect = 0.36 Identities = 26/116 (22%), Positives = 56/116 (48%), Gaps = 7/116 (6%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGR-LIGIVTSRDIDFREGD------ 164 D + + + ++D L+ KN + P+ K R L+GI++ RD+ + G Sbjct: 10 DLITVDKDQKLSDGLKLLAKNDVSRLPVINTNKDHQRELVGIISERDVADKLGSSKYENM 69 Query: 165 PHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTD 220 P L + D+I+ + L D ++ ++ G +PI+++D +V ++++ D Sbjct: 70 PASRLHISSVMVKDVISVVETMDLADVANLMLENGIGSVPIVSDDDMMVGIVSKAD 125 >UniRef50_A0B5X2 Cluster: CBS domain containing membrane protein; n=1; Methanosaeta thermophila PT|Rep: CBS domain containing membrane protein - Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrixthermophila (strain DSM 6194 / PT)) Length = 262 Score = 38.7 bits (86), Expect = 0.36 Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 16/87 (18%) Query: 146 GGRLIGIVTSRDI-----------DFREGDP---HLSLKEVMTPINDMITAQLGVTLQDA 191 GG+L+GI+T RDI +R+ + +L + +VMT +D+ + L++ Sbjct: 163 GGKLVGILTERDIARALRAFRDLVSWRQQETRIKNLLVSDVMT--HDVKYVYVDTPLEEV 220 Query: 192 NYILEKSKKGKLPIINNDGELVALIAR 218 I+ + +G LP++N+DG L +I R Sbjct: 221 RRIILEENRGGLPVLNSDGTLAGMITR 247 >UniRef50_Q57837 Cluster: Putative zinc metalloprotease MJ0392; n=6; Methanococcales|Rep: Putative zinc metalloprotease MJ0392 - Methanococcus jannaschii Length = 339 Score = 38.7 bits (86), Expect = 0.36 Identities = 31/132 (23%), Positives = 59/132 (44%), Gaps = 14/132 (10%) Query: 95 QANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVT 154 + + K K K +PV + P+ ++ + L+ K+ + GYP+ +NGK L+G + Sbjct: 212 EVETIFKNIKAKDIMTPNPVYVTPDMSIEEFLDFMLKHKYFGYPVVENGK----LVGCIG 267 Query: 155 SRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVA 214 +I +EG +++ + D D IL K + G+L Sbjct: 268 IGNIHKKEGTVRDYMEKPVVVSED----------TDIKEILRKMANTDRVFVVEGGKLKG 317 Query: 215 LIARTDLKKARS 226 +I++TD+ +A S Sbjct: 318 IISKTDILRAMS 329 >UniRef50_Q9KGA2 Cluster: BH0210 protein; n=7; Bacillaceae|Rep: BH0210 protein - Bacillus halodurans Length = 315 Score = 38.3 bits (85), Expect = 0.48 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Query: 314 ALRVGMGSGSICITQEVMACGC---PQATAVYQVASYARHFNVPVIADGGIQSVGHIIKS 370 AL+ + + + A G + T + A+ VP+IA GG+ + ++ + Sbjct: 123 ALKAEQHGADVIVAEGFEAAGLNSSEELTTFTLIPQIAKAVTVPLIAAGGVGNGAGLLAA 182 Query: 371 LALGASTVMMGSLLAGTSEA 390 L+LGA V MG+ L T EA Sbjct: 183 LSLGAQGVQMGTRLIATKEA 202 >UniRef50_Q8F624 Cluster: L-lactate dehydrogenase; n=4; Leptospira|Rep: L-lactate dehydrogenase - Leptospira interrogans Length = 760 Score = 38.3 bits (85), Expect = 0.48 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 7/99 (7%) Query: 287 TYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVAS 346 ++ ++ + ++T A+ IDAG D + V G + P V Sbjct: 614 SFTKLPFIVKGIMTPQDAQLAIDAGADCIVVSNHGGRVLDDM-------PGTARVLSGIR 666 Query: 347 YARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLA 385 + ++ADGG++S + K +ALGA TV++G +A Sbjct: 667 NVIGDKIQIVADGGVRSGMDVFKMIALGADTVLVGRPMA 705 >UniRef50_Q6AJC1 Cluster: Related to acetoin utilization protein; n=1; Desulfotalea psychrophila|Rep: Related to acetoin utilization protein - Desulfotalea psychrophila Length = 216 Score = 38.3 bits (85), Expect = 0.48 Identities = 35/146 (23%), Positives = 66/146 (45%), Gaps = 19/146 (13%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI------DFREGDP 165 +P+ + P + + F P+ +G+ RL+GI+T RD+ G+ Sbjct: 10 EPLTIYPHTLLPEARGILDAFKFRHLPVVDDGQ---RLLGIITDRDLRSAYPSSLESGEE 66 Query: 166 HLS--LKEVMTPINDMITAQLG-----VTLQDANYILEKSKKGKLPIINNDGELVALIAR 218 L TP+++++T TL DA ++ ++ K G +P++N+ +V + + Sbjct: 67 SSGKFLGVEKTPVSEIMTVNCATIHPQATLDDALFLFDREKVGGVPVVNDQDLVVGMFSI 126 Query: 219 TDLKKARSYPNASKDSNK-QLLVGAA 243 DL A Y N ++K L+G A Sbjct: 127 RDLIAA--YKNLFGVADKGSALIGIA 150 >UniRef50_Q5QUI2 Cluster: Signaling protein with a cAMP-binding, CBS domains and predicted nucleotidyltransferase domain; n=2; Idiomarina|Rep: Signaling protein with a cAMP-binding, CBS domains and predicted nucleotidyltransferase domain - Idiomarina loihiensis Length = 610 Score = 38.3 bits (85), Expect = 0.48 Identities = 31/121 (25%), Positives = 58/121 (47%), Gaps = 11/121 (9%) Query: 113 PVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---EGDP-HLS 168 PV + +V + + +G + + + +L +GI+T RD+ R EG P + Sbjct: 156 PVSLSSSTSVQEAAKLMASHGISSVLVVDDTQL----VGILTDRDLRNRVVAEGLPLDVR 211 Query: 169 LKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL-KKARSY 227 + VMT + + + +L DA + S LP++N+ + V ++ TDL ++ RS Sbjct: 212 VSSVMTQLPESVYENR--SLMDALTTMTSSNIHHLPVVNDQNQPVGMVTATDLIRQQRSD 269 Query: 228 P 228 P Sbjct: 270 P 270 >UniRef50_P74081 Cluster: PolyA polymerase; n=4; Cyanobacteria|Rep: PolyA polymerase - Synechocystis sp. (strain PCC 6803) Length = 942 Score = 38.3 bits (85), Expect = 0.48 Identities = 29/116 (25%), Positives = 54/116 (46%), Gaps = 9/116 (7%) Query: 109 FIRDPV-CMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDID--FREGDP 165 F+ PV + P T+ + G +G + + +L+GI++ RD+D G Sbjct: 334 FMSSPVRTIRPHTTIEQAQRVLFRYGHSGLTVVNQEE---KLVGIISRRDLDLALHHGFS 390 Query: 166 HLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 H +K MT ++ T L I+ G+LP+++ + +LV ++ RTD+ Sbjct: 391 HAPVKGYMT--RNVKTIAPDTPLPRIEAIMVADDVGRLPVMDQE-KLVGIVTRTDV 443 >UniRef50_Q3T556 Cluster: CBS domain-like protein; n=5; Bacteria|Rep: CBS domain-like protein - Acidithiobacillus caldus Length = 158 Score = 38.3 bits (85), Expect = 0.48 Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 3/60 (5%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKE 171 +P+ + PE VA++ ++ G P+T GRL+GIVT D+ R D L +E Sbjct: 10 NPIQIAPETAVAEIARILIEHRINGVPVTDTE---GRLLGIVTEGDLVHRAADERLEPRE 66 >UniRef50_Q11EL1 Cluster: CBS domain containing protein; n=13; Proteobacteria|Rep: CBS domain containing protein - Mesorhizobium sp. (strain BNC1) Length = 151 Score = 38.3 bits (85), Expect = 0.48 Identities = 27/116 (23%), Positives = 54/116 (46%), Gaps = 12/116 (10%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK 170 RD P++T+ D + P+ N RL+G++T RDI R L + Sbjct: 9 RDVRVASPDDTIEDAARIMAEIDAGSLPVGDND----RLVGMITDRDIAVRAVAKGLGPE 64 Query: 171 EVMTPINDMITAQLGVTLQDAN-----YILEKSKKGKLPIINNDGELVALIARTDL 221 P++D++T ++ +D + + + + +LP++N D LV +++ D+ Sbjct: 65 ---CPVSDVMTREIRYCFEDEDTDDIAHNMADQQIRRLPVVNRDKRLVGILSLGDI 117 >UniRef50_A6LV86 Cluster: Sigma54 specific transcriptional regulator, Fis family; n=2; Clostridium|Rep: Sigma54 specific transcriptional regulator, Fis family - Clostridium beijerinckii NCIMB 8052 Length = 590 Score = 38.3 bits (85), Expect = 0.48 Identities = 28/118 (23%), Positives = 53/118 (44%), Gaps = 8/118 (6%) Query: 104 KYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI-DFRE 162 K K + + + P NT + + +NG G P+ G+LI IVT D+ Sbjct: 2 KVKELMTKKVLVLKPNNTFEEAAKLFIENGIDGAPVVDRD---GKLISIVTKTDLMKAIL 58 Query: 163 GDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTD 220 ++ K + +IT + ++D + K G+LP+I+ + +++ +I TD Sbjct: 59 NKLEMNTKLETLELKKVITINSEMNIED----VLKYNVGRLPVIDKNNKIIGIITHTD 112 >UniRef50_A5URS3 Cluster: CBS domain containing protein; n=4; Chloroflexaceae|Rep: CBS domain containing protein - Roseiflexus sp. RS-1 Length = 162 Score = 38.3 bits (85), Expect = 0.48 Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 2/95 (2%) Query: 139 ITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQLGVTLQDANYILEKS 198 ITQ G L+ + D + + + EVM+ D IT +L++A ++ ++ Sbjct: 65 ITQGDIRGADLLRVAGMDPFDIADALRRIKVYEVMS--EDPITVTPETSLREAAMLMIEN 122 Query: 199 KKGKLPIINNDGELVALIARTDLKKARSYPNASKD 233 K G LP+++ + +V +I +DL +A + S+D Sbjct: 123 KIGGLPVVDENRMVVGIITESDLFEALVHVLESRD 157 >UniRef50_A4M3K4 Cluster: CBS domain containing membrane protein; n=3; Bacteria|Rep: CBS domain containing membrane protein - Geobacter bemidjiensis Bem Length = 216 Score = 38.3 bits (85), Expect = 0.48 Identities = 40/172 (23%), Positives = 73/172 (42%), Gaps = 17/172 (9%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK- 170 +P+ + P+ +V + L P+ + G+L+GIV+ RD+ P SL Sbjct: 10 NPITITPDISVTEALRLMGDKKIRRLPVVERT---GKLVGIVSDRDLFQASPSPATSLAI 66 Query: 171 -EV----------MTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIART 219 E+ T D+IT L++A ++ + G LP++ D LV +I + Sbjct: 67 WEIHDLLAKLTVDKTMATDVITVTEDTPLEEAARVMVDRRIGGLPVMKGDA-LVGIITES 125 Query: 220 DLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQ 271 DL +A + +L V G + T + + + G D++ L S+ Sbjct: 126 DLFQALLELLGGRRHGVRLTV-TTTGAKGTLADVAQTIYQAGGDIVGLGFSE 176 >UniRef50_A3ZL92 Cluster: Putative uncharacterized protein; n=1; Blastopirellula marina DSM 3645|Rep: Putative uncharacterized protein - Blastopirellula marina DSM 3645 Length = 363 Score = 38.3 bits (85), Expect = 0.48 Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 7/80 (8%) Query: 147 GRLIGIVTSRDID--FREGDPHL---SLKEVMTPINDMITAQLGVTLQDANYILEKSKKG 201 G+L GI T D+ F G L + VMT +T+ GV + +A + KSK Sbjct: 253 GKLAGIFTDSDLARIFETGRTELLDQPISIVMTQSPKTVTS--GVRVLEALSAIAKSKIS 310 Query: 202 KLPIINNDGELVALIARTDL 221 +LP+IN+ GE + ++ TDL Sbjct: 311 ELPVINDTGEPIGMLDITDL 330 >UniRef50_O27702 Cluster: Glutamate synthase (NADPH), alpha subunit related protein; n=1; Methanothermobacter thermautotrophicus str. Delta H|Rep: Glutamate synthase (NADPH), alpha subunit related protein - Methanobacterium thermoautotrophicum Length = 383 Score = 38.3 bits (85), Expect = 0.48 Identities = 30/93 (32%), Positives = 47/93 (50%), Gaps = 8/93 (8%) Query: 296 GNVVTRMQAKNLIDAGVDALRV-GMGSGSICITQEVMA-CGCPQATAVYQ----VASYAR 349 GNV ++A L+DAGVD + + G G G+ + + G P A+ + V + Sbjct: 229 GNVEDDVKA--LLDAGVDFISLDGFGGGTGAVNPHIRDNTGIPLIAAIPRAVKTVINEGH 286 Query: 350 HFNVPVIADGGIQSVGHIIKSLALGASTVMMGS 382 V +IA GG+++ + K LALGA V G+ Sbjct: 287 GDRVSLIAGGGLRTAADMAKCLALGADAVYTGT 319 >UniRef50_A3CWH3 Cluster: CBS domain containing protein; n=1; Methanoculleus marisnigri JR1|Rep: CBS domain containing protein - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 279 Score = 38.3 bits (85), Expect = 0.48 Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 6/110 (5%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKE 171 +P+ + PE + D+ +G P+ GK+ GIVT D+ R + Sbjct: 80 EPITIAPETGIRDIAAIMLDRDISGLPVVNEGKVS----GIVTKLDL-MRSAHIRGLTAQ 134 Query: 172 VMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 V + D T +L + K K KL ++N++G L +I ++L Sbjct: 135 VSEIMEDAATVNRYHSLDHVIDTI-KGKNDKLIVVNDNGSLAGIITESNL 183 >UniRef50_Q97EU8 Cluster: CBS domain containing protein; n=1; Clostridium acetobutylicum|Rep: CBS domain containing protein - Clostridium acetobutylicum Length = 133 Score = 37.9 bits (84), Expect = 0.63 Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Query: 173 MTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL-KKARSYPNAS 231 +TP ++ A+L TL+ A ++ K +L I+N+ GE V I + DL KK ++ PN Sbjct: 7 ITPKKQVVYAKLTSTLRQAFERMKYYKCHELIILNDKGEYVGFITKEDLVKKIKNSPNLH 66 Query: 232 -KDSNK 236 KD NK Sbjct: 67 LKDFNK 72 >UniRef50_Q3J9M3 Cluster: CBS domain containing protein; n=1; Nitrosococcus oceani ATCC 19707|Rep: CBS domain containing protein - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 286 Score = 37.9 bits (84), Expect = 0.63 Identities = 32/106 (30%), Positives = 59/106 (55%), Gaps = 13/106 (12%) Query: 123 ADVLEAKK--KNGFTGYPITQNGKLGGRLIGIVTSRDIDFR----EGDP-HLSLKEVMTP 175 + VLEA + +N G + Q+ GR++GIVT RD+ R + DP + ++ EVMTP Sbjct: 18 SSVLEAARAMENNSIGAIVVQDH---GRIVGIVTDRDLAVRALGHKLDPENTAITEVMTP 74 Query: 176 INDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 M+T L + ++A ++++ ++P+ N+ +V ++ DL Sbjct: 75 SPLMLT--LADSREEAIALMQQGNVRRIPLSENN-RVVGMVTLDDL 117 >UniRef50_Q8GA65 Cluster: Putative FMN-dependent dehydrogenase; n=4; Escherichia coli|Rep: Putative FMN-dependent dehydrogenase - Escherichia coli Length = 405 Score = 37.9 bits (84), Expect = 0.63 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 10/102 (9%) Query: 281 IKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATA 340 I+++K+ + V+ ++ A IDAG DA++V G G P A + Sbjct: 260 IEFVKKI-TGLPVIVKGILRGEDAVVAIDAGADAIQVSNHGGR-------QIDGVPSAIS 311 Query: 341 VYQ-VASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMG 381 Q VA+ H VPVI D GI+ ++++++LGA+ V +G Sbjct: 312 QLQEVAARVGH-KVPVIFDSGIRRGIDVVRAISLGATAVAVG 352 >UniRef50_Q3RE81 Cluster: 2-nitropropane dioxygenase, NPD precursor; n=6; Bacteria|Rep: 2-nitropropane dioxygenase, NPD precursor - Xylella fastidiosa Dixon Length = 343 Score = 37.9 bits (84), Expect = 0.63 Identities = 43/163 (26%), Positives = 70/163 (42%), Gaps = 9/163 (5%) Query: 244 IGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQ 303 +G D ++L LL+N+ V V+ + T+ + ++ I V +V + Sbjct: 106 MGDDDGWPDKLALLLNDPVPVV-------SFTFGLPAVRDIAALRCAGSRVLASVTLPAE 158 Query: 304 AKNLIDAGVDALRV-GMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQ 362 A+ ++AGVD L V G +G T + P T V V ++PVIA GG+ Sbjct: 159 AQAAMEAGVDGLVVQGPDAGGHSATYDPGRPFTPLKT-VSLVRRVCAVSSLPVIAAGGVD 217 Query: 363 SVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKY 405 + L GA+ V +G+LL T E+ D + Y Sbjct: 218 GPVMVRALLQAGAAAVAIGTLLLRTKESGATQVHKDALANPAY 260 >UniRef50_A4WYL0 Cluster: Putative uncharacterized protein; n=1; Rhodobacter sphaeroides ATCC 17025|Rep: Putative uncharacterized protein - Rhodobacter sphaeroides ATCC 17025 Length = 139 Score = 37.9 bits (84), Expect = 0.63 Identities = 29/108 (26%), Positives = 57/108 (52%), Gaps = 11/108 (10%) Query: 119 ENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---EG-DPHLS-LKEVM 173 + V++V K + P+ ++ RLIG++T RD+ R EG DP + +VM Sbjct: 17 DTPVSEVARQMKADDIGALPVGRDD----RLIGMITDRDLVLRVLAEGRDPKTTKASDVM 72 Query: 174 TPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 T ++ + + DA + +E+ + +LP+I+++ LV ++A D+ Sbjct: 73 T--EGIVWCRTSQPISDAIHQMEERRIRRLPVIDDNKRLVGMLALGDI 118 >UniRef50_A4M6L8 Cluster: 2-nitropropane dioxygenase, NPD; n=2; Bacteria|Rep: 2-nitropropane dioxygenase, NPD - Petrotoga mobilis SJ95 Length = 317 Score = 37.9 bits (84), Expect = 0.63 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 3/78 (3%) Query: 314 ALRVGMGSGSICITQEVMACG--CPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSL 371 ALR+ +G+ I E M CG T + V + +VPVIA GGI + + +L Sbjct: 126 ALRLE-NAGAEAIIGEGMECGGHIGDVTTMVLVPKLSSILSVPVIAAGGIANGPGAVAAL 184 Query: 372 ALGASTVMMGSLLAGTSE 389 +LGA + MG+ T E Sbjct: 185 SLGAEGIQMGTRFIATYE 202 >UniRef50_A1IEP7 Cluster: Putative uncharacterized protein; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Putative uncharacterized protein - Candidatus Desulfococcus oleovorans Hxd3 Length = 355 Score = 37.9 bits (84), Expect = 0.63 Identities = 21/72 (29%), Positives = 33/72 (45%) Query: 320 GSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVM 379 G+ ++ +T A ++ + N+PVIA GGI + +L LGA V Sbjct: 138 GADALIVTGHEAAAHGGAVASMVLIPGIVDRVNIPVIAAGGIADGRGLAAALVLGAEGVA 197 Query: 380 MGSLLAGTSEAP 391 MG+ T E+P Sbjct: 198 MGTRFMNTRESP 209 >UniRef50_A1I7E2 Cluster: 2-nitropropane dioxygenase, NPD; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: 2-nitropropane dioxygenase, NPD - Candidatus Desulfococcus oleovorans Hxd3 Length = 322 Score = 37.9 bits (84), Expect = 0.63 Identities = 21/48 (43%), Positives = 25/48 (52%) Query: 344 VASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAP 391 V S VPVI GG+ ++ LALGA V+MGS L T E P Sbjct: 163 VPSVVDAVKVPVIGGGGVSDGRGLLAVLALGAGAVIMGSRLLVTRECP 210 >UniRef50_O29411 Cluster: Inosine monophosphate dehydrogenase; n=1; Archaeoglobus fulgidus|Rep: Inosine monophosphate dehydrogenase - Archaeoglobus fulgidus Length = 189 Score = 37.9 bits (84), Expect = 0.63 Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 7/80 (8%) Query: 147 GRLIGIVTSRD----IDFREGDPHLSL-KEVMTPINDMITAQLGVTLQDANYILEKSKKG 201 GR +GIVT +D I R P L +EVM+ +IT +L++A I+ K Sbjct: 45 GRPVGIVTEKDLISKIVARNKVPSKVLVEEVMS--QPVITIGPNTSLREAARIMMKRGIR 102 Query: 202 KLPIINNDGELVALIARTDL 221 +LP++NN+ EL+ +I D+ Sbjct: 103 RLPVVNNNQELIGIITDNDI 122 >UniRef50_Q58410 Cluster: Uncharacterized protein MJ1004; n=6; Methanococcales|Rep: Uncharacterized protein MJ1004 - Methanococcus jannaschii Length = 214 Score = 37.9 bits (84), Expect = 0.63 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 4/106 (3%) Query: 119 ENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI-DFREGDPHLSLKEVMTPIN 177 + TV D + KK PI RL+G VT+ ++ E D + E M P+ Sbjct: 17 DETVEDAINLLKKKKRFSAPIVDKED---RLVGWVTTLELLGISEKDFKKPITEFMRPVE 73 Query: 178 DMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 ++IT ++ K K +P++ DG ++ ++ D+ K Sbjct: 74 EVITVYEDDEARNVVLKFVKYKVVSIPVLTRDGRVIGMVRNCDVVK 119 >UniRef50_A3CTR9 Cluster: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; n=4; Methanomicrobiales|Rep: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 239 Score = 37.9 bits (84), Expect = 0.63 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 2/74 (2%) Query: 319 MGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTV 378 +G+GS+ T V G Q A+ V VPV+ GGI S G + GA+ Sbjct: 157 LGAGSLLYTN-VDVEGLQQGIAIEPVTELLARVKVPVVVSGGISSPGDVAALRDAGAAGA 215 Query: 379 MMGS-LLAGTSEAP 391 ++GS L AG P Sbjct: 216 VLGSALYAGKVRLP 229 >UniRef50_UPI00015BAEC4 Cluster: putative signal-transduction protein with CBS domains; n=1; Ignicoccus hospitalis KIN4/I|Rep: putative signal-transduction protein with CBS domains - Ignicoccus hospitalis KIN4/I Length = 131 Score = 37.5 bits (83), Expect = 0.84 Identities = 30/124 (24%), Positives = 62/124 (50%), Gaps = 6/124 (4%) Query: 102 VKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR 161 ++KY G R + + E T+ + +E +NG +T+ + G G++T RD+ Sbjct: 4 IEKY-FGRERMIITIDEEATIGEAVELMHENGIGALLVTREEEGGVAAAGLLTERDVIAA 62 Query: 162 ---EGDPH-LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIA 217 DP+ +K MTP D+IT +++A I+ ++ L +++ + +++ +I+ Sbjct: 63 LALGADPNRAKVKYYMTPWKDVITVTPETPIKEALRIMIENGIRHLVVVSGE-KVLGIIS 121 Query: 218 RTDL 221 DL Sbjct: 122 MRDL 125 >UniRef50_Q9K9P0 Cluster: BH2605 protein; n=6; Bacteria|Rep: BH2605 protein - Bacillus halodurans Length = 142 Score = 37.5 bits (83), Expect = 0.84 Identities = 29/108 (26%), Positives = 59/108 (54%), Gaps = 11/108 (10%) Query: 118 PENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---EGDPHLS-LKEVM 173 P++ + +V +++ PI + +L +G+VT RDI R + P+ + +KEVM Sbjct: 17 PDDNIFEVAVKMERDNVGAVPICEEEQL----LGMVTDRDIVIRSVAKKKPNSTPVKEVM 72 Query: 174 TPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 + ++TA +T+Q+A ++ + +LP++ N+ LV + + DL Sbjct: 73 S--EHLVTATPDMTVQEAAKLMATKQIRRLPVVENN-RLVGICSLGDL 117 >UniRef50_Q3WH73 Cluster: CBS domain; n=2; Frankia|Rep: CBS domain - Frankia sp. EAN1pec Length = 139 Score = 37.5 bits (83), Expect = 0.84 Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 8/118 (6%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR---EG-DPH 166 R+P +G + +A+ K + N GR+ GIVT RDI R EG DP Sbjct: 11 RNPATVGMDQPIAEAARRMKTVNAGDVIVLDNT---GRVAGIVTDRDITLRVVAEGRDPE 67 Query: 167 LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 + + +IT T A ++ + +LP+++ G V +I+ DL +A Sbjct: 68 RTATREVCTQTGLITIAPDTTTDTAVQLIRERHIRRLPVVDK-GRPVGVISLGDLARA 124 >UniRef50_Q122S0 Cluster: 2-nitropropane dioxygenase, NPD; n=68; Betaproteobacteria|Rep: 2-nitropropane dioxygenase, NPD - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 422 Score = 37.5 bits (83), Expect = 0.84 Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 2/61 (3%) Query: 336 PQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYF 395 PQ ++ A R +P+IA GGI I++ ALGAS V +G+ A T E + Sbjct: 234 PQVLEFFKTAGIERE--IPLIAAGGINCRDDILRLQALGASAVQLGTAFAVTLECDADPA 291 Query: 396 F 396 F Sbjct: 292 F 292 >UniRef50_Q0VMM0 Cluster: 2-nitropropane dioxygenase, putative; n=1; Alcanivorax borkumensis SK2|Rep: 2-nitropropane dioxygenase, putative - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 333 Score = 37.5 bits (83), Expect = 0.84 Identities = 17/39 (43%), Positives = 25/39 (64%) Query: 352 NVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEA 390 +VPV+A GGI S G ++ + ++GA V +GS T EA Sbjct: 173 DVPVVASGGIASGGAMLAAFSMGAQGVSLGSAFLATHEA 211 >UniRef50_Q0AHF1 Cluster: Putative signal-transduction protein with CBS domains; n=2; Nitrosomonadaceae|Rep: Putative signal-transduction protein with CBS domains - Nitrosomonas eutropha (strain C71) Length = 149 Score = 37.5 bits (83), Expect = 0.84 Identities = 24/82 (29%), Positives = 44/82 (53%), Gaps = 7/82 (8%) Query: 150 IGIVTSRDIDFREGDPHLSLKEVMTPINDMITAQL-----GVTLQDANYILEKSKKGKLP 204 +G++T RD+ L KE +T ++D++T +L + DA + + +LP Sbjct: 48 VGVITDRDLVVEVLATGLD-KEAIT-VDDVMTQELFAVKENTAIHDAINFMRRKTIRRLP 105 Query: 205 IINNDGELVALIARTDLKKARS 226 IIN++GELV ++ D+ + S Sbjct: 106 IINDNGELVGILTTDDIMEILS 127 >UniRef50_A1SM43 Cluster: 2-nitropropane dioxygenase, NPD; n=1; Nocardioides sp. JS614|Rep: 2-nitropropane dioxygenase, NPD - Nocardioides sp. (strain BAA-499 / JS614) Length = 328 Score = 37.5 bits (83), Expect = 0.84 Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 8/108 (7%) Query: 294 VGGNVVTRMQAKNLIDAGVDALRV-GMGSGSICITQEVMACGCPQATAVYQVASYARHFN 352 V V T +A+ + AGVD L V G+ +G + E +A P+ V VA Sbjct: 110 VFATVGTAQEARAALAAGVDGLVVQGLEAGGHLVGVEPLAAALPR---VLDVAGD----K 162 Query: 353 VPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGV 400 VPV+A GG+ + + L GAS + G+ T E+ + + V Sbjct: 163 VPVLAAGGVADSADVRRLLESGASAAVAGTRFLLTDESAAHPVYKERV 210 >UniRef50_Q6C9A7 Cluster: Similar to sp|Q9WU19 Mus musculus Hydroxyacid oxidase 1; n=1; Yarrowia lipolytica|Rep: Similar to sp|Q9WU19 Mus musculus Hydroxyacid oxidase 1 - Yarrowia lipolytica (Candida lipolytica) Length = 382 Score = 37.5 bits (83), Expect = 0.84 Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 7/91 (7%) Query: 291 IQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARH 350 +Q+ VVT I+AGVD + V G + G A+ +V A Sbjct: 243 MQIWVKGVVTAEDTHAAIEAGVDGIWVSNHGG------RQLDSGLATIDALPEVVEAAAG 296 Query: 351 FNVPVIADGGIQSVGHIIKSLALGASTVMMG 381 VP+ DGGI+ G + K LALGA V +G Sbjct: 297 -RVPIHIDGGIRRGGDVFKCLALGADFVWLG 326 >UniRef50_Q6LXU6 Cluster: Putative uncharacterized protein; n=5; Methanococcus|Rep: Putative uncharacterized protein - Methanococcus maripaludis Length = 186 Score = 37.5 bits (83), Expect = 0.84 Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 7/108 (6%) Query: 119 ENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKEVMT---P 175 + T DV K+ G G + N G+ +GI+T RD+ +L KEV+ Sbjct: 21 DTTAYDVANILKEKGI-GCLVVLND--AGKPVGIITERDLALGVVSRNLKSKEVIVEEIS 77 Query: 176 INDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 + +I TL DA ++ +LP+I+ D EL+ ++ +D+ K Sbjct: 78 SSKLIAIAPKSTLMDAARKMDTENVKRLPVIDGD-ELLGIVTVSDITK 124 >UniRef50_Q4JBX5 Cluster: Conserved CBS domain protein; n=2; Sulfolobus|Rep: Conserved CBS domain protein - Sulfolobus acidocaldarius Length = 131 Score = 37.5 bits (83), Expect = 0.84 Identities = 29/117 (24%), Positives = 53/117 (45%), Gaps = 8/117 (6%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDP---HL 167 R PV + + ++ D + ++ G I N R +GIVT RDI + Sbjct: 9 RKPVTVDLKTSIKDATKVMRREGVGSLVIVDNDF---RPVGIVTERDIVYAIAQDIPIDT 65 Query: 168 SLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKA 224 + E+M+ D ++ G + +A ++ L +INN+G + +I+ D+ KA Sbjct: 66 PISEIMS--RDPVSINGGSDVSEAVALMTSRGIRHLVVINNEGRTIGVISVRDVVKA 120 >UniRef50_Q4JAS3 Cluster: Protein pcrB homolog; n=4; Sulfolobaceae|Rep: Protein pcrB homolog - Sulfolobus acidocaldarius Length = 257 Score = 37.5 bits (83), Expect = 0.84 Identities = 21/60 (35%), Positives = 35/60 (58%), Gaps = 2/60 (3%) Query: 261 GVDVIVLDSSQGNS-TYQIKMIKYIKETYPE-IQVVGGNVVTRMQAKNLIDAGVDALRVG 318 G+ I L++ G S T + + IK +K T + + +VGG V + +A+NL+ AG D + G Sbjct: 170 GMKYIYLEAGSGASETVKPEAIKVVKNTVKDGVVIVGGGVTSEERARNLVLAGADIIVTG 229 >UniRef50_A4FVH7 Cluster: Hao1 protein; n=9; Deuterostomia|Rep: Hao1 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 369 Score = 37.1 bits (82), Expect = 1.1 Identities = 35/126 (27%), Positives = 54/126 (42%), Gaps = 8/126 (6%) Query: 273 NSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMA 332 ++T + + I ++K T ++ VV V+T AK + GVD + V Sbjct: 214 DATVRWQDIGWLK-TLTKLPVVVKGVLTAEDAKEALKYGVDGILVSNHGARQLDGVPATI 272 Query: 333 CGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPG 392 P+ A VA V V DGG++ ++K+LALGA V +G + G Sbjct: 273 DALPEVVAA--VAG-----QVEVFMDGGVRMGSDVLKALALGAKAVFIGRPVLWALACQG 325 Query: 393 EYFFSD 398 E SD Sbjct: 326 EKGVSD 331 >UniRef50_Q9KDK7 Cluster: BH1205 protein; n=2; Bacillus|Rep: BH1205 protein - Bacillus halodurans Length = 365 Score = 37.1 bits (82), Expect = 1.1 Identities = 18/41 (43%), Positives = 25/41 (60%) Query: 350 HFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEA 390 H VPV+A GG+ ++ +LALGA+ V MG+ T EA Sbjct: 208 HVQVPVVAAGGVVDGRGLVAALALGAAGVQMGTRFLLTKEA 248 >UniRef50_Q98DX5 Cluster: Cysteine synthase; n=42; Bacteria|Rep: Cysteine synthase - Rhizobium loti (Mesorhizobium loti) Length = 479 Score = 37.1 bits (82), Expect = 1.1 Identities = 30/113 (26%), Positives = 53/113 (46%), Gaps = 7/113 (6%) Query: 112 DPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLKE 171 D V +GP+ ++ + +++ + P+ ++GK LIGIV DI + P+ E Sbjct: 363 DTVYVGPDESLLNAYGRMRRSDVSQLPVLEDGK----LIGIVDESDILAKVDGPYDGRWE 418 Query: 172 VMT-PINDMITAQLGV--TLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 P+ +T+ L Q + +L + ++ II + E V LI R DL Sbjct: 419 RFNGPVRTAMTSNLHTLQASQTLDALLPVFDRNEVAIIFDGDEFVGLITRIDL 471 >UniRef50_Q98DF1 Cluster: Glycolate oxidase (S)-2-hydroxy-acid oxidase, peroxisomal; n=1; Mesorhizobium loti|Rep: Glycolate oxidase (S)-2-hydroxy-acid oxidase, peroxisomal - Rhizobium loti (Mesorhizobium loti) Length = 352 Score = 37.1 bits (82), Expect = 1.1 Identities = 14/29 (48%), Positives = 23/29 (79%) Query: 353 VPVIADGGIQSVGHIIKSLALGASTVMMG 381 +P+I DGG++ ++K++ALGAS VM+G Sbjct: 277 IPIILDGGVRRGTDVLKAIALGASAVMIG 305 >UniRef50_Q8NQY4 Cluster: Predicted signal-transduction protein containing cAMP-binding and CBS domains; n=3; Corynebacterium|Rep: Predicted signal-transduction protein containing cAMP-binding and CBS domains - Corynebacterium glutamicum (Brevibacterium flavum) Length = 622 Score = 37.1 bits (82), Expect = 1.1 Identities = 30/118 (25%), Positives = 58/118 (49%), Gaps = 11/118 (9%) Query: 110 IRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFR----EGDP 165 I +P+ P+ T+ D + G + + ++ G L GI+T RD+ R + D Sbjct: 162 IANPISCSPDTTIMDAAIKMDEFGVSSLLV----QIDGELKGIITDRDMRSRVVAKDLDI 217 Query: 166 HLSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKK 223 L + EVMT T+Q G+ +A ++ + + LPI+ +DG++ ++ D+ + Sbjct: 218 QLPVSEVMTVDPRCATSQ-GLAF-EAMLLMSELRIHHLPIV-DDGQISGIVTAADIMR 272 >UniRef50_Q8DHZ1 Cluster: CBS domain protein; n=1; Synechococcus elongatus|Rep: CBS domain protein - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 156 Score = 37.1 bits (82), Expect = 1.1 Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 2/63 (3%) Query: 169 LKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYP 228 +++VMTP + T + + +A ++ +LP++N+ GELV +I+R DL +A Sbjct: 95 VQDVMTP--NPHTINVDAPISEAARLMVNHHISRLPVLNDQGELVGIISRHDLLRALHAQ 152 Query: 229 NAS 231 AS Sbjct: 153 EAS 155 >UniRef50_Q8CXK9 Cluster: Glutamate synthase (NADPH) large (Alpha) subunit; n=1; Oceanobacillus iheyensis|Rep: Glutamate synthase (NADPH) large (Alpha) subunit - Oceanobacillus iheyensis Length = 482 Score = 37.1 bits (82), Expect = 1.1 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 8/99 (8%) Query: 295 GGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMA--CGCPQATAVYQVASYARHFN 352 GG + + A L++ GVD + V G + ++ G P A+ + ++ N Sbjct: 275 GGKIEDDIDA--LLEIGVDYIAVDGGQAATYGAAPLLTDDFGIPTLHALIRAVNHLEKIN 332 Query: 353 ----VPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGT 387 + +I GG+ + G +K+LALGA V +GS++ T Sbjct: 333 KKNEISLIISGGMFTPGEYLKALALGADAVYLGSVMLFT 371 >UniRef50_Q5LKQ6 Cluster: Oxidoreductase, 2-nitropropane dioxygenase family; n=1; Silicibacter pomeroyi|Rep: Oxidoreductase, 2-nitropropane dioxygenase family - Silicibacter pomeroyi Length = 358 Score = 37.1 bits (82), Expect = 1.1 Identities = 19/38 (50%), Positives = 23/38 (60%) Query: 353 VPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEA 390 VPV+A GGI I +LALGAS MG+ T+EA Sbjct: 210 VPVVASGGITDGRGIAAALALGASAAQMGTAFLTTTEA 247 >UniRef50_Q3A5H4 Cluster: Putative Fe-S oxidoreductase; n=1; Pelobacter carbinolicus DSM 2380|Rep: Putative Fe-S oxidoreductase - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 425 Score = 37.1 bits (82), Expect = 1.1 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 1/85 (1%) Query: 248 DTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPE-IQVVGGNVVTRMQAKN 306 DT K +++N +DV+ + + I K+ P+ I VVGG ++T Sbjct: 46 DTKESLKKKIIDNNIDVLCIGGLSDQYNEIKRTIDLSKQIKPDLIIVVGGGLITAQPTLI 105 Query: 307 LIDAGVDALRVGMGSGSICITQEVM 331 + + G D VG G +IC E + Sbjct: 106 MENIGADYAIVGQGEITICELAEAL 130 >UniRef50_Q21UP4 Cluster: Putative signal-transduction protein with CBS domains; n=1; Rhodoferax ferrireducens T118|Rep: Putative signal-transduction protein with CBS domains - Rhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118) Length = 146 Score = 37.1 bits (82), Expect = 1.1 Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 3/70 (4%) Query: 111 RDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSLK 170 R+P +GP+ VAD + + GF PI G+++G+ + RD RE +SL Sbjct: 79 RNPQSVGPDMRVADAVVIMIERGFRHLPIINT---AGKILGVFSIRDAMPREIGNAVSLA 135 Query: 171 EVMTPINDMI 180 E +ND + Sbjct: 136 EFNDQVNDAL 145 >UniRef50_Q1Q2I4 Cluster: Putative uncharacterized protein; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Putative uncharacterized protein - Candidatus Kuenenia stuttgartiensis Length = 133 Score = 37.1 bits (82), Expect = 1.1 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 11/87 (12%) Query: 146 GGRLIGIVTSRDI----------DFREGDPHL-SLKEVMTPINDMITAQLGVTLQDANYI 194 G ++GI+T RD+ ++ E L S+K D+IT +++DA I Sbjct: 35 GKEIVGILTQRDLYKASLTSIVTNWEENKTFLDSVKVAEVMTKDVITISPNTSIEDAAQI 94 Query: 195 LEKSKKGKLPIINNDGELVALIARTDL 221 + K G LP++ + L+ LI TD+ Sbjct: 95 MIDKKVGCLPVVEDKNTLLGLITETDV 121 >UniRef50_Q1LK44 Cluster: 2-nitropropane dioxygenase, NPD; n=2; Burkholderiaceae|Rep: 2-nitropropane dioxygenase, NPD - Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) Length = 342 Score = 37.1 bits (82), Expect = 1.1 Identities = 24/71 (33%), Positives = 36/71 (50%) Query: 312 VDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSL 371 V A R+G+ + ++ +E G Q +A A +P++ GGI S I +L Sbjct: 144 VTAQRLGVDAVALVGLEEGGHPGANQLSAFVNGAFALERVEIPLVIGGGIGSGRQIAAAL 203 Query: 372 ALGASTVMMGS 382 ALGA V+MGS Sbjct: 204 ALGADGVVMGS 214 >UniRef50_A6CKR1 Cluster: Putative uncharacterized protein; n=1; Bacillus sp. SG-1|Rep: Putative uncharacterized protein - Bacillus sp. SG-1 Length = 685 Score = 37.1 bits (82), Expect = 1.1 Identities = 16/55 (29%), Positives = 35/55 (63%), Gaps = 2/55 (3%) Query: 167 LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELVALIARTDL 221 + ++++TP++ M+T + TL++A I+++ K LP+ +N G+L + R+ L Sbjct: 2 IHFQDIVTPVDCMVTEE--TTLKEAVEIIKQKKWNLLPVTDNQGDLQGIFTRSGL 54 >UniRef50_A5UUL3 Cluster: Thiamine-phosphate pyrophosphorylase; n=3; Bacteria|Rep: Thiamine-phosphate pyrophosphorylase - Roseiflexus sp. RS-1 Length = 236 Score = 37.1 bits (82), Expect = 1.1 Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 15/129 (11%) Query: 256 LLVNNGVDV-IVLDSSQ---GNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAG 311 L+VN+ VDV + LD+ G +M++ I PE +++G +V T QA+ +DAG Sbjct: 86 LIVNDRVDVALALDADGVHVGQDDIPAEMVRRI--IGPE-RILGVSVATVEQAQRAMDAG 142 Query: 312 VDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQ--SVGHIIK 369 + VG G T G P + +A AR N+PV+ GGI + +I+ Sbjct: 143 ATYVSVGDLFG----TPSKPDAGPP--IGLEPLAEIARTVNLPVLGIGGINLANAASVIR 196 Query: 370 SLALGASTV 378 + A+G + + Sbjct: 197 AGAVGVAVI 205 >UniRef50_O27292 Cluster: Inosine-5'-monophosphate dehydrogenase related protein III; n=2; Methanobacteriaceae|Rep: Inosine-5'-monophosphate dehydrogenase related protein III - Methanobacterium thermoautotrophicum Length = 313 Score = 37.1 bits (82), Expect = 1.1 Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 20/117 (17%) Query: 121 TVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVTSRDI-DFREGDPHLS----------L 169 T+ + E KN F PIT G G+L GIVT+ DI DF G L Sbjct: 47 TIKEAAEIMVKNKFRRLPITNPGT--GKLQGIVTAMDILDFLGGGDKSKIIDKKYDDNFL 104 Query: 170 KEVMTPINDMITAQ-LGVTLQDA-----NYILEKSKKGKLPIINNDGELVALIARTD 220 V P+ ++T + +T +D+ + +LE S G LP++++D ++ +++ D Sbjct: 105 AAVNEPVKSIMTRDVISITTRDSIADAVSMMLENSV-GALPVVDDDEKIAGIVSERD 160 >UniRef50_P61411 Cluster: Putative thiamine-phosphate pyrophosphorylase; n=8; Desulfuromonadales|Rep: Putative thiamine-phosphate pyrophosphorylase - Geobacter sulfurreducens Length = 213 Score = 37.1 bits (82), Expect = 1.1 Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 8/150 (5%) Query: 236 KQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYI-KETYPEIQVV 294 + LL A R TDR +LL+N+ VD+ + + G + M + +E +++ Sbjct: 47 RTLLELARAMRRLTDRFGARLLINDRVDIALAAGADGVHLGEEGMPAAVARELLGSGRLI 106 Query: 295 GGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVP 354 G + R A + G D + G + T A G P + Q+A+ + ++P Sbjct: 107 GVSCHGRGGAAAAVAQGADFITF----GPVYPTPSKAAYGEP--VGIDQLAATTKEIHIP 160 Query: 355 VIADGGIQSVGHIIKSLALGASTVMMGSLL 384 V A GGI+ +I ++LA GA+ V + S + Sbjct: 161 VFALGGIKE-ANIPEALAAGAAGVALISAI 189 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.317 0.135 0.382 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 554,303,674 Number of Sequences: 1657284 Number of extensions: 23354367 Number of successful extensions: 59824 Number of sequences better than 10.0: 398 Number of HSP's better than 10.0 without gapping: 146 Number of HSP's successfully gapped in prelim test: 252 Number of HSP's that attempted gapping in prelim test: 59317 Number of HSP's gapped (non-prelim): 569 length of query: 512 length of database: 575,637,011 effective HSP length: 104 effective length of query: 408 effective length of database: 403,279,475 effective search space: 164538025800 effective search space used: 164538025800 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 75 (34.3 bits)
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