BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001035-TA|BGIBMGA001035-PA|IPR000644|CBS, IPR001093|IMP dehydrogenase/GMP reductase, IPR005990|IMP dehydrogenase (512 letters) Database: nematostella 59,808 sequences; 16,821,457 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SB_52186| Best HMM Match : IMPDH (HMM E-Value=0) 559 e-159 SB_976| Best HMM Match : No HMM Matches (HMM E-Value=.) 305 4e-83 SB_34913| Best HMM Match : No HMM Matches (HMM E-Value=.) 129 5e-30 SB_56933| Best HMM Match : No HMM Matches (HMM E-Value=.) 51 2e-06 SB_31093| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 1.7 SB_909| Best HMM Match : Transgly_assoc (HMM E-Value=2.2) 31 2.2 SB_51975| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 2.9 SB_45057| Best HMM Match : Rhabdo_NV (HMM E-Value=4.1) 29 8.9 >SB_52186| Best HMM Match : IMPDH (HMM E-Value=0) Length = 876 Score = 559 bits (1380), Expect = e-159 Identities = 274/400 (68%), Positives = 330/400 (82%), Gaps = 4/400 (1%) Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70 DGL+A F +GLTY+DFL+LPG+IDF+A+ V+L S LT++I LK P VS+PMDTVTE Sbjct: 209 DGLTANALFGGGQGLTYDDFLILPGFIDFSADVVELNSALTREITLKTPFVSSPMDTVTE 268 Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130 + MA++MAL GGIGIIHHNC+ E+QA+EV KVKKYK GFI DP+ + P +TV DV+E KK Sbjct: 269 SAMAVAMALHGGIGIIHHNCSIEFQADEVKKVKKYKQGFINDPLVLSPRHTVKDVIEIKK 328 Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLS--LKEVMTPINDMITAQLGVTL 188 KNGF+G P+T+NG +GG L GI+TSRDIDF G + L E MTP+ND++ A+ TL Sbjct: 329 KNGFSGIPLTENGCMGGVLAGIITSRDIDFL-GPEQIDEPLSEFMTPLNDLVVAKDDCTL 387 Query: 189 QDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRD 248 Q+AN IL++SKKGKLPI+N +GELV+LIA +DL+K R +P ASKDS KQLLVGAAIGTR Sbjct: 388 QEANRILQQSKKGKLPIVNENGELVSLIAYSDLRKNREFPLASKDSKKQLLVGAAIGTRA 447 Query: 249 TDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLI 308 D+ R++ L++ GVDVI+LDSSQGNS YQI MIK IKE P +QVV GNVVT QAKNLI Sbjct: 448 EDKLRVEALIHAGVDVIILDSSQGNSAYQIDMIKNIKELCPRLQVVAGNVVTACQAKNLI 507 Query: 309 DAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHII 368 DAG DALRVGMGSGSICITQEVMA G PQATAV++VA YAR F +PVIADGGI++VGHI Sbjct: 508 DAGADALRVGMGSGSICITQEVMAVGRPQATAVFKVAEYARRFGIPVIADGGIRTVGHIT 567 Query: 369 KSLALGASTVMMGSLLAGTSEAPGEYFFS-DGVRLKKYRG 407 K+L++GASTVMMGSLLAGTSEAPGEY+FS DGVRLKKYRG Sbjct: 568 KALSVGASTVMMGSLLAGTSEAPGEYYFSNDGVRLKKYRG 607 >SB_976| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 447 Score = 305 bits (750), Expect = 4e-83 Identities = 168/306 (54%), Positives = 207/306 (67%), Gaps = 21/306 (6%) Query: 72 DMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKK 131 D + L GGIGIIHHNC+ E+QANE+ KVKK++ GFI P+ + NTVADV++AK++ Sbjct: 42 DFPATDVLNGGIGIIHHNCSIEFQANEIRKVKKFEQGFIMAPLVLSATNTVADVIDAKQR 101 Query: 132 NGFTGYPITQNGKLGGRLIGIVTSRDIDFREG-DPHLSLKEVMTPINDMITAQLGVTLQD 190 +GF+G PIT+NG+LGG L GIVTSRDIDF G + H L EVMT + D++ A+ G+TL + Sbjct: 102 HGFSGIPITENGQLGGILQGIVTSRDIDFLHGVENHKQLGEVMTRLEDLVVAKAGITLNE 161 Query: 191 ANYILEKSKK----GKLPIINNDGEL----VALI---------ARTDLKKARSYPNASKD 233 AN IL+ SKK + D L V LI D A+ D Sbjct: 162 ANKILQMSKKVLEDSPQKHLLRDWRLLCFFVVLIMTIDDGGGGGNDDDGGGNDDDGANND 221 Query: 234 ---SNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPE 290 +N VGAAIGTR+ D+ RL LV GVDV+V+DSSQGNS YQ+ +I +IKE YP Sbjct: 222 DDGANNDDDVGAAIGTREDDKARLHALVEAGVDVVVIDSSQGNSIYQLSLISHIKENYPN 281 Query: 291 IQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARH 350 +Q+VGGNVVT QAKNLIDAGVDALRVGMGSGSICITQEVMA G PQ TAVY+VA YAR Sbjct: 282 LQIVGGNVVTASQAKNLIDAGVDALRVGMGSGSICITQEVMAVGRPQGTAVYKVAEYARR 341 Query: 351 FNVPVI 356 F + V+ Sbjct: 342 FGLFVL 347 Score = 111 bits (266), Expect = 2e-24 Identities = 49/76 (64%), Positives = 65/76 (85%) Query: 431 ESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMK 490 E+DK +VAQGVSGS+VDKGS+ +F+PYL AG+QH CQDLGA+S++ LR M +SG+L+F + Sbjct: 372 ENDKVKVAQGVSGSVVDKGSIHKFVPYLTAGIQHGCQDLGAKSLTSLRSMMYSGELKFER 431 Query: 491 RTYSAQLEGNVHGLFS 506 RT S+Q+EG VHGL S Sbjct: 432 RTTSSQIEGGVHGLHS 447 Score = 44.4 bits (100), Expect = 2e-04 Identities = 19/34 (55%), Positives = 27/34 (79%), Gaps = 1/34 (2%) Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEV 44 DG++A F S+GLTY+DF++LPG+IDF A +V Sbjct: 16 DGMTAGQLF-QSDGLTYSDFIILPGFIDFPATDV 48 >SB_34913| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 125 Score = 129 bits (312), Expect = 5e-30 Identities = 61/107 (57%), Positives = 86/107 (80%), Gaps = 5/107 (4%) Query: 406 RGMGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHS 465 + MGSL+A+E+K S+ SRYF ES++ +VAQGVSG++VDKGS+ RF+PYL +G+QH Sbjct: 24 KSMGSLDALENK----SSQSRYFI-ESERIKVAQGVSGAVVDKGSIHRFVPYLLSGLQHG 78 Query: 466 CQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNVHGLFSYEKRLF 512 CQD+G +S+SVLR M +SG L+F KR+ +A++EG +H L SYEKRL+ Sbjct: 79 CQDMGCQSLSVLRSMMYSGQLKFEKRSSAARIEGGIHSLHSYEKRLY 125 >SB_56933| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 331 Score = 51.2 bits (117), Expect = 2e-06 Identities = 30/93 (32%), Positives = 51/93 (54%), Gaps = 2/93 (2%) Query: 230 ASKDSNKQLLVGAAIGTRDTDRERLKLLVN--NGVDVIVLDSSQGNSTYQIKMIKYIKET 287 AS+ S+ A+ G D D E+L+ ++ V I LD + G S + + +K ++ Sbjct: 237 ASEHSDVLPYTIASAGMADKDLEKLQKILELVPTVPGICLDVANGYSEHFVDFVKKVRSM 296 Query: 288 YPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMG 320 +PE ++ GNVVT + LI +G D ++VG+G Sbjct: 297 FPEHIIIAGNVVTGEMVEQLILSGADIVKVGIG 329 >SB_31093| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 374 Score = 31.5 bits (68), Expect = 1.7 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 7/104 (6%) Query: 290 EIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYAR 349 ++ +V ++T AK +D GVDA+ V G + P+ Q Sbjct: 190 KLPLVLKGIMTGEDAKLAVDHGVDAIIVSNHGGRQLDSVSATIDVLPEIVDAVQG----- 244 Query: 350 HFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGE 393 + V DGG++ + K+LALGA V +G + GE Sbjct: 245 --KLEVYMDGGVRLGTDVFKALALGARAVFLGRAVIWGLACKGE 286 >SB_909| Best HMM Match : Transgly_assoc (HMM E-Value=2.2) Length = 243 Score = 31.1 bits (67), Expect = 2.2 Identities = 21/77 (27%), Positives = 34/77 (44%) Query: 1 MSLKTEGDLRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPL 60 +S G L G+S E F + + L ++L G + T K L PL Sbjct: 127 LSFILSGSLIIGISCESLFKSKQELQPRSLIILSGTAAIVNGILSYIIFNTSKRLRSVPL 186 Query: 61 VSTPMDTVTEADMAISM 77 ++ +DTV EA M++ + Sbjct: 187 LTLSIDTVFEALMSLGV 203 >SB_51975| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 809 Score = 30.7 bits (66), Expect = 2.9 Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%) Query: 362 QSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKG 421 + V I+K + V + +L++G + P Y +++GVR R +L E DGK Sbjct: 346 KDVPQIVKDTLVANVGVPLKALISGLANRPLRYVYTNGVRDTSRRTSQTLPTGERLDGKK 405 Query: 422 --SAMSRYF 428 + M YF Sbjct: 406 TYAGMISYF 414 >SB_45057| Best HMM Match : Rhabdo_NV (HMM E-Value=4.1) Length = 522 Score = 29.1 bits (62), Expect = 8.9 Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Query: 415 ESKDGKGSAMS-RYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARS 473 E K G+GSA +Y K S GV G D ++R + QH Q+ G + Sbjct: 191 EHKIGRGSASRYQYRRKNSRGEGCEDGVFGGASDAIDLVRKYGFPTTVGQHLEQNEGWIT 250 Query: 474 VSVLREMSHSGDL 486 L+++ SGDL Sbjct: 251 TPELKDLLDSGDL 263 Database: nematostella Posted date: Oct 22, 2007 1:22 PM Number of letters in database: 16,821,457 Number of sequences in database: 59,808 Lambda K H 0.317 0.135 0.382 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 16,097,572 Number of Sequences: 59808 Number of extensions: 666791 Number of successful extensions: 1318 Number of sequences better than 10.0: 8 Number of HSP's better than 10.0 without gapping: 5 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 1306 Number of HSP's gapped (non-prelim): 11 length of query: 512 length of database: 16,821,457 effective HSP length: 85 effective length of query: 427 effective length of database: 11,737,777 effective search space: 5012030779 effective search space used: 5012030779 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 62 (29.1 bits)
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