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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001035-TA|BGIBMGA001035-PA|IPR000644|CBS, IPR001093|IMP
dehydrogenase/GMP reductase, IPR005990|IMP dehydrogenase
         (512 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_52186| Best HMM Match : IMPDH (HMM E-Value=0)                      559   e-159
SB_976| Best HMM Match : No HMM Matches (HMM E-Value=.)               305   4e-83
SB_34913| Best HMM Match : No HMM Matches (HMM E-Value=.)             129   5e-30
SB_56933| Best HMM Match : No HMM Matches (HMM E-Value=.)              51   2e-06
SB_31093| Best HMM Match : No HMM Matches (HMM E-Value=.)              31   1.7  
SB_909| Best HMM Match : Transgly_assoc (HMM E-Value=2.2)              31   2.2  
SB_51975| Best HMM Match : No HMM Matches (HMM E-Value=.)              31   2.9  
SB_45057| Best HMM Match : Rhabdo_NV (HMM E-Value=4.1)                 29   8.9  

>SB_52186| Best HMM Match : IMPDH (HMM E-Value=0)
          Length = 876

 Score =  559 bits (1380), Expect = e-159
 Identities = 274/400 (68%), Positives = 330/400 (82%), Gaps = 4/400 (1%)

Query: 11  DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70
           DGL+A   F   +GLTY+DFL+LPG+IDF+A+ V+L S LT++I LK P VS+PMDTVTE
Sbjct: 209 DGLTANALFGGGQGLTYDDFLILPGFIDFSADVVELNSALTREITLKTPFVSSPMDTVTE 268

Query: 71  ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130
           + MA++MAL GGIGIIHHNC+ E+QA+EV KVKKYK GFI DP+ + P +TV DV+E KK
Sbjct: 269 SAMAVAMALHGGIGIIHHNCSIEFQADEVKKVKKYKQGFINDPLVLSPRHTVKDVIEIKK 328

Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLS--LKEVMTPINDMITAQLGVTL 188
           KNGF+G P+T+NG +GG L GI+TSRDIDF  G   +   L E MTP+ND++ A+   TL
Sbjct: 329 KNGFSGIPLTENGCMGGVLAGIITSRDIDFL-GPEQIDEPLSEFMTPLNDLVVAKDDCTL 387

Query: 189 QDANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRD 248
           Q+AN IL++SKKGKLPI+N +GELV+LIA +DL+K R +P ASKDS KQLLVGAAIGTR 
Sbjct: 388 QEANRILQQSKKGKLPIVNENGELVSLIAYSDLRKNREFPLASKDSKKQLLVGAAIGTRA 447

Query: 249 TDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLI 308
            D+ R++ L++ GVDVI+LDSSQGNS YQI MIK IKE  P +QVV GNVVT  QAKNLI
Sbjct: 448 EDKLRVEALIHAGVDVIILDSSQGNSAYQIDMIKNIKELCPRLQVVAGNVVTACQAKNLI 507

Query: 309 DAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHII 368
           DAG DALRVGMGSGSICITQEVMA G PQATAV++VA YAR F +PVIADGGI++VGHI 
Sbjct: 508 DAGADALRVGMGSGSICITQEVMAVGRPQATAVFKVAEYARRFGIPVIADGGIRTVGHIT 567

Query: 369 KSLALGASTVMMGSLLAGTSEAPGEYFFS-DGVRLKKYRG 407
           K+L++GASTVMMGSLLAGTSEAPGEY+FS DGVRLKKYRG
Sbjct: 568 KALSVGASTVMMGSLLAGTSEAPGEYYFSNDGVRLKKYRG 607


>SB_976| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 447

 Score =  305 bits (750), Expect = 4e-83
 Identities = 168/306 (54%), Positives = 207/306 (67%), Gaps = 21/306 (6%)

Query: 72  DMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKK 131
           D   +  L GGIGIIHHNC+ E+QANE+ KVKK++ GFI  P+ +   NTVADV++AK++
Sbjct: 42  DFPATDVLNGGIGIIHHNCSIEFQANEIRKVKKFEQGFIMAPLVLSATNTVADVIDAKQR 101

Query: 132 NGFTGYPITQNGKLGGRLIGIVTSRDIDFREG-DPHLSLKEVMTPINDMITAQLGVTLQD 190
           +GF+G PIT+NG+LGG L GIVTSRDIDF  G + H  L EVMT + D++ A+ G+TL +
Sbjct: 102 HGFSGIPITENGQLGGILQGIVTSRDIDFLHGVENHKQLGEVMTRLEDLVVAKAGITLNE 161

Query: 191 ANYILEKSKK----GKLPIINNDGEL----VALI---------ARTDLKKARSYPNASKD 233
           AN IL+ SKK         +  D  L    V LI            D         A+ D
Sbjct: 162 ANKILQMSKKVLEDSPQKHLLRDWRLLCFFVVLIMTIDDGGGGGNDDDGGGNDDDGANND 221

Query: 234 ---SNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPE 290
              +N    VGAAIGTR+ D+ RL  LV  GVDV+V+DSSQGNS YQ+ +I +IKE YP 
Sbjct: 222 DDGANNDDDVGAAIGTREDDKARLHALVEAGVDVVVIDSSQGNSIYQLSLISHIKENYPN 281

Query: 291 IQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARH 350
           +Q+VGGNVVT  QAKNLIDAGVDALRVGMGSGSICITQEVMA G PQ TAVY+VA YAR 
Sbjct: 282 LQIVGGNVVTASQAKNLIDAGVDALRVGMGSGSICITQEVMAVGRPQGTAVYKVAEYARR 341

Query: 351 FNVPVI 356
           F + V+
Sbjct: 342 FGLFVL 347



 Score =  111 bits (266), Expect = 2e-24
 Identities = 49/76 (64%), Positives = 65/76 (85%)

Query: 431 ESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMK 490
           E+DK +VAQGVSGS+VDKGS+ +F+PYL AG+QH CQDLGA+S++ LR M +SG+L+F +
Sbjct: 372 ENDKVKVAQGVSGSVVDKGSIHKFVPYLTAGIQHGCQDLGAKSLTSLRSMMYSGELKFER 431

Query: 491 RTYSAQLEGNVHGLFS 506
           RT S+Q+EG VHGL S
Sbjct: 432 RTTSSQIEGGVHGLHS 447



 Score = 44.4 bits (100), Expect = 2e-04
 Identities = 19/34 (55%), Positives = 27/34 (79%), Gaps = 1/34 (2%)

Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEV 44
          DG++A   F  S+GLTY+DF++LPG+IDF A +V
Sbjct: 16 DGMTAGQLF-QSDGLTYSDFIILPGFIDFPATDV 48


>SB_34913| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 125

 Score =  129 bits (312), Expect = 5e-30
 Identities = 61/107 (57%), Positives = 86/107 (80%), Gaps = 5/107 (4%)

Query: 406 RGMGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHS 465
           + MGSL+A+E+K    S+ SRYF  ES++ +VAQGVSG++VDKGS+ RF+PYL +G+QH 
Sbjct: 24  KSMGSLDALENK----SSQSRYFI-ESERIKVAQGVSGAVVDKGSIHRFVPYLLSGLQHG 78

Query: 466 CQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNVHGLFSYEKRLF 512
           CQD+G +S+SVLR M +SG L+F KR+ +A++EG +H L SYEKRL+
Sbjct: 79  CQDMGCQSLSVLRSMMYSGQLKFEKRSSAARIEGGIHSLHSYEKRLY 125


>SB_56933| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 331

 Score = 51.2 bits (117), Expect = 2e-06
 Identities = 30/93 (32%), Positives = 51/93 (54%), Gaps = 2/93 (2%)

Query: 230 ASKDSNKQLLVGAAIGTRDTDRERLKLLVN--NGVDVIVLDSSQGNSTYQIKMIKYIKET 287
           AS+ S+      A+ G  D D E+L+ ++     V  I LD + G S + +  +K ++  
Sbjct: 237 ASEHSDVLPYTIASAGMADKDLEKLQKILELVPTVPGICLDVANGYSEHFVDFVKKVRSM 296

Query: 288 YPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMG 320
           +PE  ++ GNVVT    + LI +G D ++VG+G
Sbjct: 297 FPEHIIIAGNVVTGEMVEQLILSGADIVKVGIG 329


>SB_31093| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 374

 Score = 31.5 bits (68), Expect = 1.7
 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 7/104 (6%)

Query: 290 EIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYAR 349
           ++ +V   ++T   AK  +D GVDA+ V    G    +        P+     Q      
Sbjct: 190 KLPLVLKGIMTGEDAKLAVDHGVDAIIVSNHGGRQLDSVSATIDVLPEIVDAVQG----- 244

Query: 350 HFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGE 393
              + V  DGG++    + K+LALGA  V +G  +       GE
Sbjct: 245 --KLEVYMDGGVRLGTDVFKALALGARAVFLGRAVIWGLACKGE 286


>SB_909| Best HMM Match : Transgly_assoc (HMM E-Value=2.2)
          Length = 243

 Score = 31.1 bits (67), Expect = 2.2
 Identities = 21/77 (27%), Positives = 34/77 (44%)

Query: 1   MSLKTEGDLRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPL 60
           +S    G L  G+S E  F + + L     ++L G        +      T K L   PL
Sbjct: 127 LSFILSGSLIIGISCESLFKSKQELQPRSLIILSGTAAIVNGILSYIIFNTSKRLRSVPL 186

Query: 61  VSTPMDTVTEADMAISM 77
           ++  +DTV EA M++ +
Sbjct: 187 LTLSIDTVFEALMSLGV 203


>SB_51975| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 809

 Score = 30.7 bits (66), Expect = 2.9
 Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%)

Query: 362 QSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKG 421
           + V  I+K   +    V + +L++G +  P  Y +++GVR    R   +L   E  DGK 
Sbjct: 346 KDVPQIVKDTLVANVGVPLKALISGLANRPLRYVYTNGVRDTSRRTSQTLPTGERLDGKK 405

Query: 422 --SAMSRYF 428
             + M  YF
Sbjct: 406 TYAGMISYF 414


>SB_45057| Best HMM Match : Rhabdo_NV (HMM E-Value=4.1)
          Length = 522

 Score = 29.1 bits (62), Expect = 8.9
 Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 1/73 (1%)

Query: 415 ESKDGKGSAMS-RYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARS 473
           E K G+GSA   +Y  K S       GV G   D   ++R   +     QH  Q+ G  +
Sbjct: 191 EHKIGRGSASRYQYRRKNSRGEGCEDGVFGGASDAIDLVRKYGFPTTVGQHLEQNEGWIT 250

Query: 474 VSVLREMSHSGDL 486
              L+++  SGDL
Sbjct: 251 TPELKDLLDSGDL 263


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.317    0.135    0.382 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 16,097,572
Number of Sequences: 59808
Number of extensions: 666791
Number of successful extensions: 1318
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1306
Number of HSP's gapped (non-prelim): 11
length of query: 512
length of database: 16,821,457
effective HSP length: 85
effective length of query: 427
effective length of database: 11,737,777
effective search space: 5012030779
effective search space used: 5012030779
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 62 (29.1 bits)

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