Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001035-TA|BGIBMGA001035-PA|IPR000644|CBS, IPR001093|IMP
dehydrogenase/GMP reductase, IPR005990|IMP dehydrogenase
(512 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC033622-1|AAH33622.2| 563|Homo sapiens IMP (inosine monophosph... 739 0.0
J05272-1|AAA36114.1| 514|Homo sapiens protein ( Human IMP dehyd... 725 0.0
L39210-1|AAB70699.1| 514|Homo sapiens inosine monophosphate deh... 725 0.0
L33842-1|AAA67054.1| 514|Homo sapiens inosine monophosphate deh... 725 0.0
BC015567-1|AAH15567.1| 514|Homo sapiens IMP (inosine monophosph... 725 0.0
BC012840-1|AAH12840.1| 514|Homo sapiens IMP (inosine monophosph... 725 0.0
BC006124-1|AAH06124.1| 514|Homo sapiens IMP (inosine monophosph... 725 0.0
J04208-1|AAA36112.1| 514|Homo sapiens protein ( Human inosine-5... 722 0.0
AK131294-1|BAD18464.1| 530|Homo sapiens protein ( Homo sapiens ... 712 0.0
AK054640-1|BAB70780.1| 489|Homo sapiens protein ( Homo sapiens ... 667 0.0
AY545560-1|AAS50155.1| 162|Homo sapiens IMP dehydrogenase 2 pro... 202 2e-51
BC093039-1|AAH93039.1| 348|Homo sapiens guanosine monophosphate... 124 8e-28
BC009832-1|AAH09832.1| 348|Homo sapiens guanosine monophosphate... 124 8e-28
BC008021-1|AAH08021.2| 366|Homo sapiens guanosine monophosphate... 124 8e-28
AF419346-1|AAN32701.1| 348|Homo sapiens guanosine monophosphate... 124 8e-28
AF135159-1|AAG09132.1| 348|Homo sapiens GMP reductase protein. 124 8e-28
AB032903-1|BAA93080.1| 348|Homo sapiens guanosine monophosphate... 124 8e-28
CR457156-1|CAG33437.1| 348|Homo sapiens GMPR2 protein. 123 2e-27
BC003053-1|AAH03053.1| 409|Homo sapiens GMPR2 protein protein. 121 5e-27
AL138883-1|CAI19917.1| 345|Homo sapiens guanosine monophosphate... 119 3e-26
AL009031-1|CAI21422.1| 345|Homo sapiens guanosine monophosphate... 119 3e-26
M24470-1|AAA52498.1| 345|Homo sapiens glucose-6-phosphate dehyd... 116 2e-25
BC008281-1|AAH08281.1| 345|Homo sapiens guanosine monophosphate... 116 2e-25
AF086919-1|AAP97149.1| 350|Homo sapiens GMP dehydrogenase protein. 111 4e-24
AY491522-1|AAR84630.1| 66|Homo sapiens inosine monophosphate d... 94 1e-18
L08114-1|AAA36113.1| 54|Homo sapiens inosine monophosphate deh... 80 2e-14
BC127892-1|AAI27893.1| 82|Homo sapiens Unknown (protein for MG... 76 3e-13
AY491523-1|AAR84631.1| 31|Homo sapiens inosine monophosphate d... 61 1e-08
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 33 2.4
BC113667-1|AAI13668.1| 370|Homo sapiens hydroxyacid oxidase (gl... 32 5.5
BC113665-1|AAI13666.1| 370|Homo sapiens hydroxyacid oxidase (gl... 32 5.5
BC036050-1|AAH36050.1| 715|Homo sapiens coiled-coil domain cont... 32 5.5
AL121739-1|CAB57329.1| 370|Homo sapiens hypothetical protein pr... 32 5.5
AL021879-1|CAC34364.1| 370|Homo sapiens hydroxyacid oxidase (gl... 32 5.5
AK058196-1|BAB71711.1| 276|Homo sapiens protein ( Homo sapiens ... 32 5.5
AF244134-1|AAF63219.1| 370|Homo sapiens glycolate oxidase protein. 32 5.5
AF231916-1|AAF40199.1| 370|Homo sapiens short chain 2-hydroxy a... 32 5.5
BC020863-1|AAH20863.1| 351|Homo sapiens hydroxyacid oxidase 2 (... 31 7.3
AY513277-1|AAT08030.1| 351|Homo sapiens growth-inhibiting prote... 31 7.3
AL359553-3|CAC19798.1| 351|Homo sapiens hydroxyacid oxidase 2 (... 31 7.3
AL359553-1|CAI23077.1| 364|Homo sapiens hydroxyacid oxidase 2 (... 31 7.3
AF231917-1|AAF40200.1| 351|Homo sapiens long-chain 2-hydroxy ac... 31 7.3
AB024079-1|BAA82872.1| 370|Homo sapiens protein ( Homo sapiens ... 31 7.3
Z73420-3|CAA97763.1| 297|Homo sapiens mercaptopyruvate sulfurtr... 31 9.7
X59434-1|CAA42060.1| 296|Homo sapiens thiosulfate sulfurtransfe... 31 9.7
CR541712-1|CAG46513.1| 297|Homo sapiens MPST protein. 31 9.7
CR456523-1|CAG30409.1| 297|Homo sapiens MPST protein. 31 9.7
BT019636-1|AAV38442.1| 297|Homo sapiens mercaptopyruvate sulfur... 31 9.7
BC018717-1|AAH18717.1| 297|Homo sapiens mercaptopyruvate sulfur... 31 9.7
BC016737-1|AAH16737.1| 297|Homo sapiens mercaptopyruvate sulfur... 31 9.7
BC003508-1|AAH03508.1| 297|Homo sapiens mercaptopyruvate sulfur... 31 9.7
>BC033622-1|AAH33622.2| 563|Homo sapiens IMP (inosine
monophosphate) dehydrogenase 1 protein.
Length = 563
Score = 739 bits (1826), Expect = 0.0
Identities = 355/503 (70%), Positives = 419/503 (83%), Gaps = 5/503 (0%)
Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70
DGL+A+ FA+++GLTYNDFL+LPG+IDF A+EVDLTS LT+KI LK PL+S+PMDTVTE
Sbjct: 65 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 124
Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130
ADMAI+MAL GGIG IHHNCTPE+QANEV KVKK++ GFI DPV + P +TV DVLEAK
Sbjct: 125 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 184
Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSL-KEVMTPINDMITAQLGVTLQ 189
++GF+G PIT+ G +G +L+GIVTSRDIDF H +L EVMTP +++ A GVTL+
Sbjct: 185 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 244
Query: 190 DANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDT 249
+AN IL++SKKGKLPI+N+ ELVA+IARTDLKK R YP ASKDS KQLL GAA+GTR+
Sbjct: 245 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 304
Query: 250 DRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309
D+ RL LL GVDVIVLDSSQGNS YQI M+ YIK+ YP +QV+GGNVVT QAKNLID
Sbjct: 305 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 364
Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369
AGVD LRVGMG GSICITQEVMACG PQ TAVY+VA YAR F VP+IADGGIQ+VGH++K
Sbjct: 365 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 424
Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH 429
+LALGASTVMMGSLLA T+EAPGEYFFSDGVRLKKYRGMGSL+AME S+ RYF
Sbjct: 425 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEK---SSSSQKRYF- 480
Query: 430 KESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFM 489
E DK ++AQGVSGSI DKGS+ +F+PYL AG+QH CQD+GARS+SVLR M +SG+L+F
Sbjct: 481 SEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFE 540
Query: 490 KRTYSAQLEGNVHGLFSYEKRLF 512
KRT SAQ+EG VHGL SYEKRL+
Sbjct: 541 KRTMSAQIEGGVHGLHSYEKRLY 563
>J05272-1|AAA36114.1| 514|Homo sapiens protein ( Human IMP
dehydrogenase type 1 mRNA complete cds. ).
Length = 514
Score = 725 bits (1793), Expect = 0.0
Identities = 349/503 (69%), Positives = 413/503 (82%), Gaps = 5/503 (0%)
Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70
DGL+A+ FA+++ LTYNDFL+LPG+IDF A+EVDLTS LT+KI LK PL+S+PMDTVTE
Sbjct: 16 DGLTAQQLFASADDLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130
ADMAI+MAL GGIG IHHNCTPE+QANEV KVK ++ GFI DPV + P +TV DVLEAK
Sbjct: 76 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKNFEQGFITDPVVLSPSHTVGDVLEAKM 135
Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSL-KEVMTPINDMITAQLGVTLQ 189
++GF+G PIT+ G +G +L+GIVTSRDIDF H +L EVMTP +++ A GVTL+
Sbjct: 136 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 195
Query: 190 DANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDT 249
+AN IL++SKKGKLPI+N+ ELVA+IARTDLKK R YP ASKDS KQLL GAA+GTR+
Sbjct: 196 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 255
Query: 250 DRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309
D+ RL LL GVDVIV SSQGNS YQI M+ YIK+ YP +QV+GGNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQAGVDVIVFHSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 315
Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369
AGVD LRVGMG GSICITQEVMACG PQ TAVY+VA YAR F VP+IADGGIQ+VGH++K
Sbjct: 316 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 375
Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH 429
+LALGASTVMMGSLLA T+EAPGEYFFSDGVRLKKYRGMGSL+ ME S+ RYF
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDPMEK---SSSSQKRYF- 431
Query: 430 KESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFM 489
E DK ++AQGVSGSI DKGS+ +F+PYL AG+QH CQD+GARS+SVLR M +SG+L+F
Sbjct: 432 SEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFE 491
Query: 490 KRTYSAQLEGNVHGLFSYEKRLF 512
KRT S Q+EG VHGL SYEKRL+
Sbjct: 492 KRTMSPQIEGGVHGLHSYEKRLY 514
>L39210-1|AAB70699.1| 514|Homo sapiens inosine monophosphate
dehydrogenase type II protein.
Length = 514
Score = 725 bits (1792), Expect = 0.0
Identities = 350/503 (69%), Positives = 418/503 (83%), Gaps = 5/503 (0%)
Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70
DGL+A+ F +GLTYNDFL+LPGYIDFTA++VDLTS LTKKI LK PLVS+PMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130
A MAI+MAL GGIG IHHNCTPE+QANEV KVKKY+ GFI DPV + P++ V DV EAK
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPH-LSLKEVMTPINDMITAQLGVTLQ 189
++GF G PIT G++G RL+GI++SRDIDF + + H L+E+MT D++ A G+TL+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLK 195
Query: 190 DANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDT 249
+AN IL++SKKGKLPI+N D ELVA+IARTDLKK R YP ASKD+ KQLL GAAIGT +
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309
D+ RL LL GVDV+VLDSSQGNS +QI MIKYIK+ YP +QV+GGNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369
AGVDALRVGMGSGSICITQEV+ACG PQATAVY+V+ YAR F VPVIADGGIQ+VGHI K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH 429
+LALGASTVMMGSLLA T+EAPGEYFFSDG+RLKKYRGMGSL+AM D S+ +RYF
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM---DKHLSSQNRYF- 431
Query: 430 KESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFM 489
E+DK +VAQGVSG++ DKGS+ +F+PYL AG+QHSCQD+GA+S++ +R M +SG+L+F
Sbjct: 432 SEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFE 491
Query: 490 KRTYSAQLEGNVHGLFSYEKRLF 512
KRT SAQ+EG VH L SYEKRLF
Sbjct: 492 KRTSSAQVEGGVHSLHSYEKRLF 514
>L33842-1|AAA67054.1| 514|Homo sapiens inosine monophosphate
dehydrogenase type II protein.
Length = 514
Score = 725 bits (1792), Expect = 0.0
Identities = 350/503 (69%), Positives = 418/503 (83%), Gaps = 5/503 (0%)
Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70
DGL+A+ F +GLTYNDFL+LPGYIDFTA++VDLTS LTKKI LK PLVS+PMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130
A MAI+MAL GGIG IHHNCTPE+QANEV KVKKY+ GFI DPV + P++ V DV EAK
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPH-LSLKEVMTPINDMITAQLGVTLQ 189
++GF G PIT G++G RL+GI++SRDIDF + + H L+E+MT D++ A G+TL+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLK 195
Query: 190 DANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDT 249
+AN IL++SKKGKLPI+N D ELVA+IARTDLKK R YP ASKD+ KQLL GAAIGT +
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309
D+ RL LL GVDV+VLDSSQGNS +QI MIKYIK+ YP +QV+GGNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369
AGVDALRVGMGSGSICITQEV+ACG PQATAVY+V+ YAR F VPVIADGGIQ+VGHI K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH 429
+LALGASTVMMGSLLA T+EAPGEYFFSDG+RLKKYRGMGSL+AM D S+ +RYF
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM---DKHLSSQNRYF- 431
Query: 430 KESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFM 489
E+DK +VAQGVSG++ DKGS+ +F+PYL AG+QHSCQD+GA+S++ +R M +SG+L+F
Sbjct: 432 SEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFE 491
Query: 490 KRTYSAQLEGNVHGLFSYEKRLF 512
KRT SAQ+EG VH L SYEKRLF
Sbjct: 492 KRTSSAQVEGGVHSLHSYEKRLF 514
>BC015567-1|AAH15567.1| 514|Homo sapiens IMP (inosine
monophosphate) dehydrogenase 2 protein.
Length = 514
Score = 725 bits (1792), Expect = 0.0
Identities = 350/503 (69%), Positives = 418/503 (83%), Gaps = 5/503 (0%)
Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70
DGL+A+ F +GLTYNDFL+LPGYIDFTA++VDLTS LTKKI LK PLVS+PMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130
A MAI+MAL GGIG IHHNCTPE+QANEV KVKKY+ GFI DPV + P++ V DV EAK
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPH-LSLKEVMTPINDMITAQLGVTLQ 189
++GF G PIT G++G RL+GI++SRDIDF + + H L+E+MT D++ A G+TL+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLK 195
Query: 190 DANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDT 249
+AN IL++SKKGKLPI+N D ELVA+IARTDLKK R YP ASKD+ KQLL GAAIGT +
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309
D+ RL LL GVDV+VLDSSQGNS +QI MIKYIK+ YP +QV+GGNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369
AGVDALRVGMGSGSICITQEV+ACG PQATAVY+V+ YAR F VPVIADGGIQ+VGHI K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH 429
+LALGASTVMMGSLLA T+EAPGEYFFSDG+RLKKYRGMGSL+AM D S+ +RYF
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM---DKHLSSQNRYF- 431
Query: 430 KESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFM 489
E+DK +VAQGVSG++ DKGS+ +F+PYL AG+QHSCQD+GA+S++ +R M +SG+L+F
Sbjct: 432 SEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFE 491
Query: 490 KRTYSAQLEGNVHGLFSYEKRLF 512
KRT SAQ+EG VH L SYEKRLF
Sbjct: 492 KRTSSAQVEGGVHSLHSYEKRLF 514
>BC012840-1|AAH12840.1| 514|Homo sapiens IMP (inosine
monophosphate) dehydrogenase 2 protein.
Length = 514
Score = 725 bits (1792), Expect = 0.0
Identities = 350/503 (69%), Positives = 418/503 (83%), Gaps = 5/503 (0%)
Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70
DGL+A+ F +GLTYNDFL+LPGYIDFTA++VDLTS LTKKI LK PLVS+PMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130
A MAI+MAL GGIG IHHNCTPE+QANEV KVKKY+ GFI DPV + P++ V DV EAK
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPH-LSLKEVMTPINDMITAQLGVTLQ 189
++GF G PIT G++G RL+GI++SRDIDF + + H L+E+MT D++ A G+TL+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLK 195
Query: 190 DANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDT 249
+AN IL++SKKGKLPI+N D ELVA+IARTDLKK R YP ASKD+ KQLL GAAIGT +
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309
D+ RL LL GVDV+VLDSSQGNS +QI MIKYIK+ YP +QV+GGNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369
AGVDALRVGMGSGSICITQEV+ACG PQATAVY+V+ YAR F VPVIADGGIQ+VGHI K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH 429
+LALGASTVMMGSLLA T+EAPGEYFFSDG+RLKKYRGMGSL+AM D S+ +RYF
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM---DKHLSSQNRYF- 431
Query: 430 KESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFM 489
E+DK +VAQGVSG++ DKGS+ +F+PYL AG+QHSCQD+GA+S++ +R M +SG+L+F
Sbjct: 432 SEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFE 491
Query: 490 KRTYSAQLEGNVHGLFSYEKRLF 512
KRT SAQ+EG VH L SYEKRLF
Sbjct: 492 KRTSSAQVEGGVHSLHSYEKRLF 514
>BC006124-1|AAH06124.1| 514|Homo sapiens IMP (inosine
monophosphate) dehydrogenase 2 protein.
Length = 514
Score = 725 bits (1792), Expect = 0.0
Identities = 350/503 (69%), Positives = 418/503 (83%), Gaps = 5/503 (0%)
Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70
DGL+A+ F +GLTYNDFL+LPGYIDFTA++VDLTS LTKKI LK PLVS+PMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130
A MAI+MAL GGIG IHHNCTPE+QANEV KVKKY+ GFI DPV + P++ V DV EAK
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPH-LSLKEVMTPINDMITAQLGVTLQ 189
++GF G PIT G++G RL+GI++SRDIDF + + H L+E+MT D++ A G+TL+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLK 195
Query: 190 DANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDT 249
+AN IL++SKKGKLPI+N D ELVA+IARTDLKK R YP ASKD+ KQLL GAAIGT +
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309
D+ RL LL GVDV+VLDSSQGNS +QI MIKYIK+ YP +QV+GGNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369
AGVDALRVGMGSGSICITQEV+ACG PQATAVY+V+ YAR F VPVIADGGIQ+VGHI K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH 429
+LALGASTVMMGSLLA T+EAPGEYFFSDG+RLKKYRGMGSL+AM D S+ +RYF
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM---DKHLSSQNRYF- 431
Query: 430 KESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFM 489
E+DK +VAQGVSG++ DKGS+ +F+PYL AG+QHSCQD+GA+S++ +R M +SG+L+F
Sbjct: 432 SEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFE 491
Query: 490 KRTYSAQLEGNVHGLFSYEKRLF 512
KRT SAQ+EG VH L SYEKRLF
Sbjct: 492 KRTSSAQVEGGVHSLHSYEKRLF 514
>J04208-1|AAA36112.1| 514|Homo sapiens protein ( Human
inosine-5'-monophosphate dehydrogenase (IMP) mRNA,
complete cds. ).
Length = 514
Score = 722 bits (1785), Expect = 0.0
Identities = 349/503 (69%), Positives = 417/503 (82%), Gaps = 5/503 (0%)
Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70
DGL+A+ F +GLTYNDFL+LPGYIDFTA++VDLTS LTKKI LK PLVS+PMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130
A MAI+MAL GGIG IHHNCTPE+QANEV KVKKY+ GFI DPV + P++ V DV EAK
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPH-LSLKEVMTPINDMITAQLGVTLQ 189
++GF G PIT G++G RL+GI++SRDIDF + + H L+E+MT D++ A +TL+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPRSITLK 195
Query: 190 DANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDT 249
+AN IL++SKKGKLPI+N D ELVA+IARTDLKK R YP ASKD+ KQLL GAAIGT +
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309
D+ RL LL GVDV+VLDSSQGNS +QI MIKYIK+ YP +QV+GGNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369
AGVDALRVGMGSGSICITQEV+ACG PQATAVY+V+ YAR F VPVIADGGIQ+VGHI K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH 429
+LALGASTVMMGSLLA T+EAPGEYFFSDG+RLKKYRGMGSL+AM D S+ +RYF
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM---DKHLSSQNRYF- 431
Query: 430 KESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFM 489
E+DK +VAQGVSG++ DKGS+ +F+PYL AG+QHSCQD+GA+S++ +R M +SG+L+F
Sbjct: 432 SEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFE 491
Query: 490 KRTYSAQLEGNVHGLFSYEKRLF 512
KRT SAQ+EG VH L SYEKRLF
Sbjct: 492 KRTSSAQVEGGVHSLHSYEKRLF 514
>AK131294-1|BAD18464.1| 530|Homo sapiens protein ( Homo sapiens
cDNA FLJ16255 fis, clone HLUNG2015548, highly similar
to INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 1 (EC
1.1.1.205). ).
Length = 530
Score = 712 bits (1759), Expect = 0.0
Identities = 343/486 (70%), Positives = 403/486 (82%), Gaps = 5/486 (1%)
Query: 28 NDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTEADMAISMALCGGIGIIH 87
+DFL+LPG+IDF A+EVDLTS LT+KI LK PL+S+PMDTVTEADMA +MAL GGIG IH
Sbjct: 49 SDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAFAMALMGGIGFIH 108
Query: 88 HNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGG 147
HNCTPE+QANEV KVKK++ GFI DPV + P +TV DVLEAK ++GF+G PIT+ G +G
Sbjct: 109 HNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGS 168
Query: 148 RLIGIVTSRDIDFREGDPHLSL-KEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPII 206
+L+GIVTSRDIDF H +L EVMTP +++ A GVTL++AN IL++SKKGKLPI+
Sbjct: 169 KLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIV 228
Query: 207 NNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNGVDVIV 266
N+ ELVA+IARTDLKK R YP ASKDS KQLL GAA+GTR+ D+ RL LL GVDVIV
Sbjct: 229 NDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIV 288
Query: 267 LDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICI 326
LDSSQGNS YQI M+ YIK+ YP +QV+GGNVVT QAKNLIDAGVD LRVGMG GSICI
Sbjct: 289 LDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICI 348
Query: 327 TQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAG 386
TQEVMACG PQ TAVY+VA YAR F VP+IADGGIQ+VGH++K+LALGASTVMMGSLLA
Sbjct: 349 TQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAA 408
Query: 387 TSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGVSGSIV 446
T+EAPGEYFFSDGVRLKKYRGMGSL+AME S+ RYF E DK ++AQGVSGSI
Sbjct: 409 TTEAPGEYFFSDGVRLKKYRGMGSLDAMEK---SSSSQKRYF-SEGDKVKIAQGVSGSIQ 464
Query: 447 DKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNVHGLFS 506
DKGS+ +F+PYL AG+QH CQD+GARS+SVLR M +SG+L+F KRT SAQ+EG VHGL S
Sbjct: 465 DKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHS 524
Query: 507 YEKRLF 512
YEKRL+
Sbjct: 525 YEKRLY 530
>AK054640-1|BAB70780.1| 489|Homo sapiens protein ( Homo sapiens
cDNA FLJ30078 fis, clone BGGI12000533, highly similar to
INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 (EC 1.1.1.205).
).
Length = 489
Score = 667 bits (1649), Expect = 0.0
Identities = 334/503 (66%), Positives = 397/503 (78%), Gaps = 30/503 (5%)
Query: 11 DGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTPMDTVTE 70
DGL+A+ FA+++GLTYNDFL+LPG+IDF A+EVDLTS LT+KI LK PL+S+PMDTVTE
Sbjct: 16 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 71 ADMAISMALCGGIGIIHHNCTPEYQANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKK 130
ADMAI+MA K++ GFI DPV + P +TV DVLEAK
Sbjct: 76 ADMAIAMA-------------------------KFEQGFITDPVVLSPSHTVGDVLEAKM 110
Query: 131 KNGFTGYPITQNGKLGGRLIGIVTSRDIDFREGDPHLSL-KEVMTPINDMITAQLGVTLQ 189
++GF+G PIT+ G +G +L+GIVTSRDIDF H +L EVMTP +++ A GVTL+
Sbjct: 111 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 170
Query: 190 DANYILEKSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDT 249
+AN IL++SKKGKLPI+N+ ELVA+IARTDLKK R YP ASKDS KQLL GAA+GTR+
Sbjct: 171 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 230
Query: 250 DRERLKLLVNNGVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLID 309
D+ RL LL GVDVIVLDSSQGNS YQI M+ YIK+ YP +QV+GGNVVT QAKNLID
Sbjct: 231 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 290
Query: 310 AGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIK 369
AGVD LRVGMG GSICITQEVMACG PQ TAVY+VA YAR F VP+IADGGIQ+VGH++K
Sbjct: 291 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 350
Query: 370 SLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESKDGKGSAMSRYFH 429
+LALGASTVMMGSLLA T+EAPGEYFFSDGVRLKKYRGMGSL+AME S+ RYF
Sbjct: 351 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEK---SSSSQKRYF- 406
Query: 430 KESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMSHSGDLRFM 489
E DK ++AQGVSGSI DKGS+ +F+PYL AG+QH CQD+GARS+SVLR M +SG+L+F
Sbjct: 407 SEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFE 466
Query: 490 KRTYSAQLEGNVHGLFSYEKRLF 512
KRT SAQ+EG VHGL SYEKRL+
Sbjct: 467 KRTMSAQIEGGVHGLHSYEKRLY 489
>AY545560-1|AAS50155.1| 162|Homo sapiens IMP dehydrogenase 2
protein.
Length = 162
Score = 202 bits (494), Expect = 2e-51
Identities = 96/160 (60%), Positives = 123/160 (76%), Gaps = 1/160 (0%)
Query: 95 QANEVHKVKKYKHGFIRDPVCMGPENTVADVLEAKKKNGFTGYPITQNGKLGGRLIGIVT 154
QANEV KVKKY+ GFI DPV + P++ V DV EAK ++GF G PIT G++G RL+GI++
Sbjct: 3 QANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIIS 62
Query: 155 SRDIDFREGDPH-LSLKEVMTPINDMITAQLGVTLQDANYILEKSKKGKLPIINNDGELV 213
SRDIDF + + H L+E+MT D++ A G+TL++AN IL++SKKGKLPI+N D ELV
Sbjct: 63 SRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELV 122
Query: 214 ALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRER 253
A+IARTDLKK R YP ASKD+ KQLL GAAIGT + D+ R
Sbjct: 123 AIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYR 162
>BC093039-1|AAH93039.1| 348|Homo sapiens guanosine monophosphate
reductase 2 protein.
Length = 348
Score = 124 bits (299), Expect = 8e-28
Identities = 76/240 (31%), Positives = 128/240 (53%), Gaps = 13/240 (5%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
+ A+ GT +D E+L+ ++ V I LD + G S + ++ +K +++ +P+ ++ GN
Sbjct: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T++ G PQ +AV + A A +I+
Sbjct: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS 218
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G +LAG SE+ GE DG + K + GM S AM+
Sbjct: 219 DGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY 278
Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477
G G A ++R ++G + + KG V + + G++ +C +GA + L
Sbjct: 279 AG-GVA----------EYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 327
>BC009832-1|AAH09832.1| 348|Homo sapiens guanosine monophosphate
reductase 2 protein.
Length = 348
Score = 124 bits (299), Expect = 8e-28
Identities = 76/240 (31%), Positives = 128/240 (53%), Gaps = 13/240 (5%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
+ A+ GT +D E+L+ ++ V I LD + G S + ++ +K +++ +P+ ++ GN
Sbjct: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T++ G PQ +AV + A A +I+
Sbjct: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS 218
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G +LAG SE+ GE DG + K + GM S AM+
Sbjct: 219 DGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY 278
Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477
G G A ++R ++G + + KG V + + G++ +C +GA + L
Sbjct: 279 AG-GVA----------EYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 327
>BC008021-1|AAH08021.2| 366|Homo sapiens guanosine monophosphate
reductase 2 protein.
Length = 366
Score = 124 bits (299), Expect = 8e-28
Identities = 76/240 (31%), Positives = 128/240 (53%), Gaps = 13/240 (5%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
+ A+ GT +D E+L+ ++ V I LD + G S + ++ +K +++ +P+ ++ GN
Sbjct: 117 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 176
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T++ G PQ +AV + A A +I+
Sbjct: 177 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS 236
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G +LAG SE+ GE DG + K + GM S AM+
Sbjct: 237 DGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY 296
Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477
G G A ++R ++G + + KG V + + G++ +C +GA + L
Sbjct: 297 AG-GVA----------EYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 345
>AF419346-1|AAN32701.1| 348|Homo sapiens guanosine monophosphate
reductase 2 protein.
Length = 348
Score = 124 bits (299), Expect = 8e-28
Identities = 76/240 (31%), Positives = 128/240 (53%), Gaps = 13/240 (5%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
+ A+ GT +D E+L+ ++ V I LD + G S + ++ +K +++ +P+ ++ GN
Sbjct: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T++ G PQ +AV + A A +I+
Sbjct: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS 218
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G +LAG SE+ GE DG + K + GM S AM+
Sbjct: 219 DGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY 278
Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477
G G A ++R ++G + + KG V + + G++ +C +GA + L
Sbjct: 279 AG-GVA----------EYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 327
>AF135159-1|AAG09132.1| 348|Homo sapiens GMP reductase protein.
Length = 348
Score = 124 bits (299), Expect = 8e-28
Identities = 76/240 (31%), Positives = 128/240 (53%), Gaps = 13/240 (5%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
+ A+ GT +D E+L+ ++ V I LD + G S + ++ +K +++ +P+ ++ GN
Sbjct: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T++ G PQ +AV + A A +I+
Sbjct: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS 218
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G +LAG SE+ GE DG + K + GM S AM+
Sbjct: 219 DGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY 278
Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477
G G A ++R ++G + + KG V + + G++ +C +GA + L
Sbjct: 279 AG-GVA----------EYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 327
>AB032903-1|BAA93080.1| 348|Homo sapiens guanosine monophosphate
reductase isolog protein.
Length = 348
Score = 124 bits (299), Expect = 8e-28
Identities = 76/240 (31%), Positives = 128/240 (53%), Gaps = 13/240 (5%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
+ A+ GT +D E+L+ ++ V I LD + G S + ++ +K +++ +P+ ++ GN
Sbjct: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T++ G PQ +AV + A A +I+
Sbjct: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS 218
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G +LAG SE+ GE DG + K + GM S AM+
Sbjct: 219 DGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY 278
Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477
G G A ++R ++G + + KG V + + G++ +C +GA + L
Sbjct: 279 AG-GVA----------EYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 327
>CR457156-1|CAG33437.1| 348|Homo sapiens GMPR2 protein.
Length = 348
Score = 123 bits (296), Expect = 2e-27
Identities = 76/240 (31%), Positives = 127/240 (52%), Gaps = 13/240 (5%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
+ A+ GT +D E+L+ ++ V I LD + G S + ++ +K +++ +P+ ++ GN
Sbjct: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T++ G PQ AV + A A +I+
Sbjct: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLGAVMECADAAHGLKGHIIS 218
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G +LAG SE+ GE DG + K + GM S AM+
Sbjct: 219 DGGCNCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY 278
Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477
G G A ++R ++G + + KG V + + G++ +C +GA + L
Sbjct: 279 AG-GVA----------EYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 327
>BC003053-1|AAH03053.1| 409|Homo sapiens GMPR2 protein protein.
Length = 409
Score = 121 bits (292), Expect = 5e-27
Identities = 68/190 (35%), Positives = 107/190 (56%), Gaps = 3/190 (1%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
+ A+ GT +D E+L+ ++ V I LD + G S + ++ +K +++ +P+ ++ GN
Sbjct: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T++ G PQ +AV + A A +I+
Sbjct: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS 218
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G +LAG SE+ GE DG + K + GM S AM+
Sbjct: 219 DGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY 278
Query: 418 DGKGSAMSRY 427
G G A RY
Sbjct: 279 AG-GVAEYRY 287
>AL138883-1|CAI19917.1| 345|Homo sapiens guanosine monophosphate
reductase protein.
Length = 345
Score = 119 bits (286), Expect = 3e-26
Identities = 73/240 (30%), Positives = 123/240 (51%), Gaps = 13/240 (5%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
V + G+ D E++ ++ V I LD + G S + ++ +K ++ +PE ++ GN
Sbjct: 99 VAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGN 158
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T+ G PQ +AV + A A +I+
Sbjct: 159 VVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIIS 218
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G + +G +E GE F +G +LK + GM S AM +K
Sbjct: 219 DGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAM-NK 277
Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477
G A ++R ++G + + KG V + + G++ +C +GA + L
Sbjct: 278 HAGGVA----------EYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKEL 327
>AL009031-1|CAI21422.1| 345|Homo sapiens guanosine monophosphate
reductase protein.
Length = 345
Score = 119 bits (286), Expect = 3e-26
Identities = 73/240 (30%), Positives = 123/240 (51%), Gaps = 13/240 (5%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
V + G+ D E++ ++ V I LD + G S + ++ +K ++ +PE ++ GN
Sbjct: 99 VAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGN 158
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T+ G PQ +AV + A A +I+
Sbjct: 159 VVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIIS 218
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G + +G +E GE F +G +LK + GM S AM +K
Sbjct: 219 DGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAM-NK 277
Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477
G A ++R ++G + + KG V + + G++ +C +GA + L
Sbjct: 278 HAGGVA----------EYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKEL 327
>M24470-1|AAA52498.1| 345|Homo sapiens glucose-6-phosphate
dehydrogenase protein.
Length = 345
Score = 116 bits (280), Expect = 2e-25
Identities = 72/240 (30%), Positives = 122/240 (50%), Gaps = 13/240 (5%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
V + G+ D E++ ++ V I LD + G S + ++ +K ++ +PE ++ GN
Sbjct: 99 VAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGN 158
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T+ G PQ +AV + A A +I+
Sbjct: 159 VVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIIS 218
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G + +G +E GE +G +LK + GM S AM +K
Sbjct: 219 DGGCTCPGDVAKAFGTGADFVMLGGMFSGHTECAGEVIERNGRKLKLFYGMSSDTAM-NK 277
Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477
G A ++R ++G + + KG V + + G++ +C +GA + L
Sbjct: 278 HAGGVA----------EYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKEL 327
>BC008281-1|AAH08281.1| 345|Homo sapiens guanosine monophosphate
reductase protein.
Length = 345
Score = 116 bits (280), Expect = 2e-25
Identities = 72/240 (30%), Positives = 122/240 (50%), Gaps = 13/240 (5%)
Query: 240 VGAAIGTRDTDRERLKLLVNN--GVDVIVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGN 297
V + G+ D E++ ++ V I LD + G S + ++ +K ++ +PE ++ GN
Sbjct: 99 VAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGN 158
Query: 298 VVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQATAVYQVASYARHFNVPVIA 357
VVT + LI +G D ++VG+G GS+C T+ G PQ +AV + A A +I+
Sbjct: 159 VVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIIS 218
Query: 358 DGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMESK 417
DGG G + K+ GA VM+G + +G +E GE +G +LK + GM S AM +K
Sbjct: 219 DGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVIERNGRKLKLFYGMSSDTAM-NK 277
Query: 418 DGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVL 477
G A ++R ++G + + KG V + + G++ +C +GA + L
Sbjct: 278 HAGGVA----------EYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKEL 327
>AF086919-1|AAP97149.1| 350|Homo sapiens GMP dehydrogenase protein.
Length = 350
Score = 111 bits (268), Expect = 4e-24
Identities = 64/200 (32%), Positives = 107/200 (53%), Gaps = 11/200 (5%)
Query: 278 IKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSICITQEVMACGCPQ 337
++ +K +++ +P+ ++ GNVVT + LI +G D ++VG+G GS+C T++ G PQ
Sbjct: 141 VEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQ 200
Query: 338 ATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEYFFS 397
+AV + A A +I+DGG G + K+ GA VM+G +LAG SE+ GE
Sbjct: 201 LSAVMECADAAHGLKGTIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIER 260
Query: 398 DGVRLKKYRGMGSLEAMESKDGKGSAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPY 457
DG + K + GM S AM+ G G A ++R ++G + + KG V +
Sbjct: 261 DGKKYKLFYGMSSEMAMKKYAG-GVA----------EYRASEGKTVEVPFKGDVEHTIRD 309
Query: 458 LQAGMQHSCQDLGARSVSVL 477
+ G++ +C +GA + L
Sbjct: 310 ILGGIRSTCTYVGAAKLKEL 329
>AY491522-1|AAR84630.1| 66|Homo sapiens inosine monophosphate
dehydrogenase type II protein.
Length = 66
Score = 93.9 bits (223), Expect = 1e-18
Identities = 46/66 (69%), Positives = 52/66 (78%)
Query: 202 KLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKLLVNNG 261
KLPI+N D ELVA+IARTDLKK R YP ASKD+ KQLL GAAIGT + D+ RL LL G
Sbjct: 1 KLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAG 60
Query: 262 VDVIVL 267
VDV+VL
Sbjct: 61 VDVVVL 66
>L08114-1|AAA36113.1| 54|Homo sapiens inosine monophosphate
dehydrogenase protein.
Length = 54
Score = 79.8 bits (188), Expect = 2e-14
Identities = 35/53 (66%), Positives = 45/53 (84%)
Query: 460 AGMQHSCQDLGARSVSVLREMSHSGDLRFMKRTYSAQLEGNVHGLFSYEKRLF 512
AG+QHSCQD+GA+S++ +R M +SG+L+F KRT SAQ+EG VH L SYEKRLF
Sbjct: 2 AGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 54
>BC127892-1|AAI27893.1| 82|Homo sapiens Unknown (protein for
MGC:158030) protein.
Length = 82
Score = 76.2 bits (179), Expect = 3e-13
Identities = 42/91 (46%), Positives = 56/91 (61%), Gaps = 14/91 (15%)
Query: 422 SAMSRYFHKESDKHRVAQGVSGSIVDKGSVLRFLPYLQAGMQHSCQDLGARSVSVLREMS 481
S+ RYF E +K + QGVS SI DKGS+ +F+PYL A QH M
Sbjct: 6 SSQKRYF-SEGEKVNIVQGVSASIQDKGSIQKFVPYLIASNQHG-------------SMM 51
Query: 482 HSGDLRFMKRTYSAQLEGNVHGLFSYEKRLF 512
+SG+L+F K T SAQ+EG VHGL +Y+K+L+
Sbjct: 52 YSGELKFEKWTMSAQIEGGVHGLHAYQKQLY 82
>AY491523-1|AAR84631.1| 31|Homo sapiens inosine monophosphate
dehydrogenase type II protein.
Length = 31
Score = 60.9 bits (141), Expect = 1e-08
Identities = 29/31 (93%), Positives = 29/31 (93%)
Query: 299 VTRMQAKNLIDAGVDALRVGMGSGSICITQE 329
VT QAKNLIDAGVDALRVGMGSGSICITQE
Sbjct: 1 VTAAQAKNLIDAGVDALRVGMGSGSICITQE 31
>AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein.
Length = 1416
Score = 33.1 bits (72), Expect = 2.4
Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 197 KSKKGKLPIINNDGELVALIARTDLKKARSYPNASKDSNKQLLVGAAIGTRDTDRERLKL 256
K KG+ P++ I + + + + K + L++G G RD +++
Sbjct: 163 KDVKGRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDA----VEV 218
Query: 257 LVNNGVDVIVLDSSQGNSTYQIKM 280
L+ NG D+ +LD+ +S+Y ++
Sbjct: 219 LIKNGADISLLDALGHDSSYYARI 242
>BC113667-1|AAI13668.1| 370|Homo sapiens hydroxyacid oxidase
(glycolate oxidase) 1 protein.
Length = 370
Score = 31.9 bits (69), Expect = 5.5
Identities = 21/71 (29%), Positives = 30/71 (42%)
Query: 334 GCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGE 393
G P V A V V DGG++ ++K+LALGA V +G + GE
Sbjct: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326
Query: 394 YFFSDGVRLKK 404
D + + K
Sbjct: 327 KGVQDVLEILK 337
>BC113665-1|AAI13666.1| 370|Homo sapiens hydroxyacid oxidase
(glycolate oxidase) 1 protein.
Length = 370
Score = 31.9 bits (69), Expect = 5.5
Identities = 21/71 (29%), Positives = 30/71 (42%)
Query: 334 GCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGE 393
G P V A V V DGG++ ++K+LALGA V +G + GE
Sbjct: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326
Query: 394 YFFSDGVRLKK 404
D + + K
Sbjct: 327 KGVQDVLEILK 337
>BC036050-1|AAH36050.1| 715|Homo sapiens coiled-coil domain
containing 13 protein.
Length = 715
Score = 31.9 bits (69), Expect = 5.5
Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 265 IVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSI 324
+++ S+G T ++ I+E E+Q +TR+ AK DAG R MG ++
Sbjct: 146 LLMAESEGAKTRVKQLTNRIQELERELQTA----LTRLSAKGATDAGAKPPRAQMGDRAL 201
Query: 325 CITQEVMA 332
T EV A
Sbjct: 202 LETPEVKA 209
>AL121739-1|CAB57329.1| 370|Homo sapiens hypothetical protein
protein.
Length = 370
Score = 31.9 bits (69), Expect = 5.5
Identities = 21/71 (29%), Positives = 30/71 (42%)
Query: 334 GCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGE 393
G P V A V V DGG++ ++K+LALGA V +G + GE
Sbjct: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326
Query: 394 YFFSDGVRLKK 404
D + + K
Sbjct: 327 KGVQDVLEILK 337
>AL021879-1|CAC34364.1| 370|Homo sapiens hydroxyacid oxidase
(glycolate oxidase) 1 protein.
Length = 370
Score = 31.9 bits (69), Expect = 5.5
Identities = 21/71 (29%), Positives = 30/71 (42%)
Query: 334 GCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGE 393
G P V A V V DGG++ ++K+LALGA V +G + GE
Sbjct: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326
Query: 394 YFFSDGVRLKK 404
D + + K
Sbjct: 327 KGVQDVLEILK 337
>AK058196-1|BAB71711.1| 276|Homo sapiens protein ( Homo sapiens
cDNA FLJ25467 fis, clone TST09387. ).
Length = 276
Score = 31.9 bits (69), Expect = 5.5
Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 265 IVLDSSQGNSTYQIKMIKYIKETYPEIQVVGGNVVTRMQAKNLIDAGVDALRVGMGSGSI 324
+++ S+G T ++ I+E E+Q +TR+ AK DAG R MG ++
Sbjct: 146 LLMAESEGAKTRVKQLTNRIQELERELQTA----LTRLSAKGATDAGAKPPRAQMGDRAL 201
Query: 325 CITQEVMA 332
T EV A
Sbjct: 202 LETPEVKA 209
>AF244134-1|AAF63219.1| 370|Homo sapiens glycolate oxidase protein.
Length = 370
Score = 31.9 bits (69), Expect = 5.5
Identities = 21/71 (29%), Positives = 30/71 (42%)
Query: 334 GCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGE 393
G P V A V V DGG++ ++K+LALGA V +G + GE
Sbjct: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326
Query: 394 YFFSDGVRLKK 404
D + + K
Sbjct: 327 KGVQDVLEILK 337
>AF231916-1|AAF40199.1| 370|Homo sapiens short chain 2-hydroxy acid
oxidase HAOX1 protein.
Length = 370
Score = 31.9 bits (69), Expect = 5.5
Identities = 21/71 (29%), Positives = 30/71 (42%)
Query: 334 GCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGE 393
G P V A V V DGG++ ++K+LALGA V +G + GE
Sbjct: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326
Query: 394 YFFSDGVRLKK 404
D + + K
Sbjct: 327 KGVQDVLEILK 337
>BC020863-1|AAH20863.1| 351|Homo sapiens hydroxyacid oxidase 2
(long chain) protein.
Length = 351
Score = 31.5 bits (68), Expect = 7.3
Identities = 13/42 (30%), Positives = 24/42 (57%)
Query: 353 VPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEY 394
+ V DGG+++ ++K+LALGA + +G + GE+
Sbjct: 272 IEVYLDGGVRTGNDVLKALALGAKCIFLGRPILWGLACKGEH 313
>AY513277-1|AAT08030.1| 351|Homo sapiens growth-inhibiting protein
16 protein.
Length = 351
Score = 31.5 bits (68), Expect = 7.3
Identities = 13/42 (30%), Positives = 24/42 (57%)
Query: 353 VPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEY 394
+ V DGG+++ ++K+LALGA + +G + GE+
Sbjct: 272 IEVYLDGGVRTGNDVLKALALGAKCIFLGRPILWGLACKGEH 313
>AL359553-3|CAC19798.1| 351|Homo sapiens hydroxyacid oxidase 2
(long chain) protein.
Length = 351
Score = 31.5 bits (68), Expect = 7.3
Identities = 13/42 (30%), Positives = 24/42 (57%)
Query: 353 VPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEY 394
+ V DGG+++ ++K+LALGA + +G + GE+
Sbjct: 272 IEVYLDGGVRTGNDVLKALALGAKCIFLGRPILWGLACKGEH 313
>AL359553-1|CAI23077.1| 364|Homo sapiens hydroxyacid oxidase 2
(long chain) protein.
Length = 364
Score = 31.5 bits (68), Expect = 7.3
Identities = 13/42 (30%), Positives = 24/42 (57%)
Query: 353 VPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEY 394
+ V DGG+++ ++K+LALGA + +G + GE+
Sbjct: 285 IEVYLDGGVRTGNDVLKALALGAKCIFLGRPILWGLACKGEH 326
>AF231917-1|AAF40200.1| 351|Homo sapiens long-chain 2-hydroxy acid
oxidase HAOX2 protein.
Length = 351
Score = 31.5 bits (68), Expect = 7.3
Identities = 13/42 (30%), Positives = 24/42 (57%)
Query: 353 VPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGEY 394
+ V DGG+++ ++K+LALGA + +G + GE+
Sbjct: 272 IEVYLDGGVRTGNDVLKALALGAKCIFLGRPILWGLACKGEH 313
>AB024079-1|BAA82872.1| 370|Homo sapiens protein ( Homo sapiens
mRNA for liver specific gene product, complete cds. ).
Length = 370
Score = 31.5 bits (68), Expect = 7.3
Identities = 21/71 (29%), Positives = 30/71 (42%)
Query: 334 GCPQATAVYQVASYARHFNVPVIADGGIQSVGHIIKSLALGASTVMMGSLLAGTSEAPGE 393
G P V A V V DGG++ ++K+LALGA V +G + GE
Sbjct: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326
Query: 394 YFFSDGVRLKK 404
D + + K
Sbjct: 327 KGVQDVLXILK 337
>Z73420-3|CAA97763.1| 297|Homo sapiens mercaptopyruvate
sulfurtransferase protein.
Length = 297
Score = 31.1 bits (67), Expect = 9.7
Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 5 TEGDLRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTP 64
TE + RDG+ + + + DFL G ++ + EE+ KK+ L PLV+T
Sbjct: 192 TEPEPRDGIEPGH-IPGTVNIPFTDFLSQEG-LEKSPEEIRHLFQ-EKKVDLSKPLVATC 248
Query: 65 MDTVTEADMAISMALCG 81
VT +A+ LCG
Sbjct: 249 GSGVTACHVALGAYLCG 265
>X59434-1|CAA42060.1| 296|Homo sapiens thiosulfate
sulfurtransferase protein.
Length = 296
Score = 31.1 bits (67), Expect = 9.7
Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 5 TEGDLRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTP 64
TE + RDG+ + + + DFL G ++ + EE+ KK+ L PLV+T
Sbjct: 191 TEPEPRDGIEPGH-IPGTVNIPFTDFLSQEG-LEKSPEEIRHLFQ-EKKVDLSKPLVATC 247
Query: 65 MDTVTEADMAISMALCG 81
VT +A+ LCG
Sbjct: 248 GSGVTACHVALGAYLCG 264
>CR541712-1|CAG46513.1| 297|Homo sapiens MPST protein.
Length = 297
Score = 31.1 bits (67), Expect = 9.7
Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 5 TEGDLRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTP 64
TE + RDG+ + + + DFL G ++ + EE+ KK+ L PLV+T
Sbjct: 192 TEPEPRDGIEPGH-IPGTVNIPFTDFLSQEG-LEKSPEEIRHLFQ-EKKVDLSKPLVATC 248
Query: 65 MDTVTEADMAISMALCG 81
VT +A+ LCG
Sbjct: 249 GSGVTACHVALGAYLCG 265
>CR456523-1|CAG30409.1| 297|Homo sapiens MPST protein.
Length = 297
Score = 31.1 bits (67), Expect = 9.7
Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 5 TEGDLRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTP 64
TE + RDG+ + + + DFL G ++ + EE+ KK+ L PLV+T
Sbjct: 192 TEPEPRDGIEPGH-IPGTVNIPFTDFLSQEG-LEKSPEEIRHLFQ-EKKVDLSKPLVATC 248
Query: 65 MDTVTEADMAISMALCG 81
VT +A+ LCG
Sbjct: 249 GSGVTACHVALGAYLCG 265
>BT019636-1|AAV38442.1| 297|Homo sapiens mercaptopyruvate
sulfurtransferase protein.
Length = 297
Score = 31.1 bits (67), Expect = 9.7
Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 5 TEGDLRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTP 64
TE + RDG+ + + + DFL G ++ + EE+ KK+ L PLV+T
Sbjct: 192 TEPEPRDGIEPGH-IPGTVNIPFTDFLSQEG-LEKSPEEIRHLFQ-EKKVDLSKPLVATC 248
Query: 65 MDTVTEADMAISMALCG 81
VT +A+ LCG
Sbjct: 249 GSGVTACHVALGAYLCG 265
>BC018717-1|AAH18717.1| 297|Homo sapiens mercaptopyruvate
sulfurtransferase protein.
Length = 297
Score = 31.1 bits (67), Expect = 9.7
Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 5 TEGDLRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTP 64
TE + RDG+ + + + DFL G ++ + EE+ KK+ L PLV+T
Sbjct: 192 TEPEPRDGIEPGH-IPGTVNIPFTDFLSQEG-LEKSPEEIRHLFQ-EKKVDLSKPLVATC 248
Query: 65 MDTVTEADMAISMALCG 81
VT +A+ LCG
Sbjct: 249 GSGVTACHVALGAYLCG 265
>BC016737-1|AAH16737.1| 297|Homo sapiens mercaptopyruvate
sulfurtransferase protein.
Length = 297
Score = 31.1 bits (67), Expect = 9.7
Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 5 TEGDLRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTP 64
TE + RDG+ + + + DFL G ++ + EE+ KK+ L PLV+T
Sbjct: 192 TEPEPRDGIEPGH-IPGTVNIPFTDFLSQEG-LEKSPEEIRHLFQ-EKKVDLSKPLVATC 248
Query: 65 MDTVTEADMAISMALCG 81
VT +A+ LCG
Sbjct: 249 GSGVTACHVALGAYLCG 265
>BC003508-1|AAH03508.1| 297|Homo sapiens mercaptopyruvate
sulfurtransferase protein.
Length = 297
Score = 31.1 bits (67), Expect = 9.7
Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 5 TEGDLRDGLSAEDTFANSEGLTYNDFLLLPGYIDFTAEEVDLTSPLTKKILLKAPLVSTP 64
TE + RDG+ + + + DFL G ++ + EE+ KK+ L PLV+T
Sbjct: 192 TEPEPRDGIEPGH-IPGTVNIPFTDFLSQEG-LEKSPEEIRHLFQ-EKKVDLSKPLVATC 248
Query: 65 MDTVTEADMAISMALCG 81
VT +A+ LCG
Sbjct: 249 GSGVTACHVALGAYLCG 265
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.317 0.135 0.382
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 69,378,140
Number of Sequences: 224733
Number of extensions: 2865018
Number of successful extensions: 4947
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 4871
Number of HSP's gapped (non-prelim): 53
length of query: 512
length of database: 73,234,838
effective HSP length: 93
effective length of query: 419
effective length of database: 52,334,669
effective search space: 21928226311
effective search space used: 21928226311
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 67 (31.1 bits)
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