BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001013-TA|BGIBMGA001013-PA|IPR002290|Serine/threonine protein kinase, IPR000719|Protein kinase, IPR008271|Serine/threonine protein kinase, active site, IPR001245|Tyrosine protein kinase, IPR011009|Protein kinase-like (360 letters) Database: spombe 5004 sequences; 2,362,478 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosac... 153 3e-38 SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |S... 151 1e-37 SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |S... 144 2e-35 SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schiz... 142 5e-35 SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |S... 138 1e-33 SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Sch... 133 3e-32 SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|c... 128 9e-31 SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase P... 125 8e-30 SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizo... 125 1e-29 SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosac... 124 3e-29 SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase... 122 6e-29 SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizos... 122 8e-29 SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1... 120 2e-28 SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosa... 119 7e-28 SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccha... 118 1e-27 SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalyt... 117 2e-27 SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosacc... 111 1e-25 SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizo... 111 1e-25 SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces ... 111 2e-25 SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc... 109 6e-25 SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosa... 109 8e-25 SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizo... 109 8e-25 SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosac... 104 2e-23 SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces... 101 1e-22 SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase ... 101 1e-22 SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizos... 101 2e-22 SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosa... 101 2e-22 SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|... 100 6e-22 SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2... 99 8e-22 SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1||... 99 8e-22 SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharom... 99 1e-21 SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosacc... 94 3e-20 SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizo... 94 3e-20 SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomy... 93 4e-20 SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schi... 92 1e-19 SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosacchar... 92 1e-19 SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizos... 91 2e-19 SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Sc... 91 3e-19 SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosa... 90 4e-19 SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe... 87 3e-18 SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccha... 86 6e-18 SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosa... 86 6e-18 SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Sch... 86 8e-18 SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosacchar... 86 8e-18 SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|S... 86 8e-18 SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizos... 85 1e-17 SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Sch... 85 1e-17 SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyc... 85 2e-17 SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schiz... 83 8e-17 SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosacch... 83 8e-17 SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces po... 82 1e-16 SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase S... 82 1e-16 SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase ki... 81 2e-16 SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosacch... 81 3e-16 SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomy... 79 1e-15 SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizo... 79 1e-15 SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyc... 77 4e-15 SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|ch... 77 5e-15 SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating ... 77 5e-15 SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizo... 76 7e-15 SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosac... 75 2e-14 SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity prote... 75 2e-14 SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schiz... 75 2e-14 SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosa... 74 3e-14 SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Pp... 73 5e-14 SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schiz... 73 6e-14 SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomy... 72 1e-13 SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosa... 72 1e-13 SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizos... 71 2e-13 SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosac... 71 3e-13 SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gc... 69 8e-13 SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccha... 69 1e-12 SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosac... 69 1e-12 SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizos... 67 3e-12 SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizo... 66 7e-12 SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Sch... 64 2e-11 SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schi... 63 7e-11 SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizos... 61 2e-10 SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |... 58 1e-09 SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizos... 56 6e-09 SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizos... 56 1e-08 SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein k... 53 7e-08 SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Sch... 51 2e-07 SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schi... 50 7e-07 SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizo... 49 9e-07 SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schi... 48 3e-06 SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizo... 47 5e-06 SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosac... 46 6e-06 SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosacchar... 46 8e-06 SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk... 45 1e-05 SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizos... 45 2e-05 SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosa... 44 3e-05 SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizo... 42 2e-04 SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizos... 41 2e-04 SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces po... 39 0.001 SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosa... 36 0.007 SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schiz... 36 0.007 SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizos... 35 0.020 SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosa... 34 0.036 SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosacchar... 31 0.33 SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces p... 30 0.44 SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizos... 30 0.58 SPBC2D10.13 |est1||telomerase regulator Est1|Schizosaccharomyces... 29 1.3 SPCC63.05 |||TAP42 family protein |Schizosaccharomyces pombe|chr... 28 1.8 SPAC17D4.04 ||SPAC458.01|tRNA |Schizosaccharomyces pombe|chr 1||... 28 1.8 SPAC3A12.13c |||translation initiation factor eIF3 complex subun... 28 2.3 SPBC15D4.01c ||SPBC2D10.21c|kinesin-like protein|Schizosaccharom... 27 3.1 SPCC74.06 |mak3|phk2|histidine kinase Mak3 |Schizosaccharomyces ... 27 4.1 SPAC1B1.04c |||poly|Schizosaccharomyces pombe|chr 1|||Manual 27 4.1 SPBC336.14c |ppk26||serine/threonine protein kinase Ppk26|Schizo... 27 4.1 SPAC343.04c |gnr1||heterotrimeric G protein beta subunit Gnr1|Sc... 27 4.1 SPAC144.05 |||ATP-dependent DNA helicase|Schizosaccharomyces pom... 26 7.2 SPAC29A4.09 |||rRNA processing protein Rrp17|Schizosaccharomyces... 26 7.2 SPAC1782.09c |clp1|flp1|Cdc14-related protein phosphatase Clp1/F... 26 7.2 SPAC1952.02 |||ribosome biogenesis protein|Schizosaccharomyces p... 26 9.5 SPAC11G7.06c |mug132||S. pombe specific UPF0300 family protein 3... 26 9.5 SPAC16E8.12c |||sequence orphan|Schizosaccharomyces pombe|chr 1|... 26 9.5 >SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosaccharomyces pombe|chr 3|||Manual Length = 460 Score = 153 bits (372), Expect = 3e-38 Identities = 84/283 (29%), Positives = 151/283 (53%), Gaps = 14/283 (4%) Query: 12 TQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMAC---KVIDTAKAPRDYL 68 +Q ++ + + + + +G G++A V A + ++I K++ T+ R Sbjct: 155 SQKNMIKSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKR--A 212 Query: 69 TKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSR 128 T+ RE+D+L ++HP +V IF+ + FI + + E GDL+DFL NG+I E + Sbjct: 213 TEMFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCK 272 Query: 129 LWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYC 188 ++Q++ L ++H + HRD+K EN+L+T ++++KI+DFG A+ + ET+C Sbjct: 273 PLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVI--HGTGTFLETFC 330 Query: 189 GSLSYAAPEVLKGV------PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVM 242 G++ Y APEVLK Y K+ D+WS+G +LY ML ++PF +S K E Sbjct: 331 GTMGYLAPEVLKSKNVNLDGGYDDKV-DIWSLGCVLYVMLTASIPFASSSQAKCIELISK 389 Query: 243 RKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTW 285 + + N++S E + + +++E P+ R + S W Sbjct: 390 GAYPIEPLLENEISEEGIDLINRMLEINPEKRISESEALQHPW 432 >SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 891 Score = 151 bits (366), Expect = 1e-37 Identities = 84/278 (30%), Positives = 148/278 (53%), Gaps = 22/278 (7%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIM-------------ACKVIDTAKAPRDYLTK 70 ++L K IG GS KV A H+ + +I A + KA + K Sbjct: 125 YVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKNK 184 Query: 71 FLP--RELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSR 128 + RE + + HP+I +++ + Y++ F + G +LD++ +G + E Q+R Sbjct: 185 EIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQAR 244 Query: 129 LWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYC 188 ++RQI S L Y+H ++ HRDLK EN+L++ ++KI DFG + R++ R T+C Sbjct: 245 KFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLYRRQSR---LRTFC 301 Query: 189 GSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFR 248 GSL +AAPE+L PY+ D+WS G++LY ++ +PF++ ++ L+ K ++K Sbjct: 302 GSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAK--IKKG--T 357 Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286 + LS++CK +++++ +P R T V N W+ Sbjct: 358 VEYPSYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWM 395 >SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 445 Score = 144 bits (348), Expect = 2e-35 Identities = 96/290 (33%), Positives = 153/290 (52%), Gaps = 30/290 (10%) Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80 E+ I ++++G G ++++Y A +D ACK+ID K F E+ +L Sbjct: 157 ERFNITQRLLGIGGFSRIYMA---MDNNTGGQYACKIIDKKKISTKRF--FEDHEMTILR 211 Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140 +++HP+I+ V+ + ++FIF GDL +LT+ G +PE + M QI+ GL+Y Sbjct: 212 KLDHPNIIKVNMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQILQGLKY 271 Query: 141 IHTMNIAHRDLKCENVLVTAN----YNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAP 196 +H NI HRDLK EN+L+ ++ + + +TDFG AR +++ R LS T+ G+ Y AP Sbjct: 272 LHEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCMQKGKR--LS-TFVGTPEYTAP 328 Query: 197 EV--LKGVPYMP--------KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWR 246 E+ LKG + K D+WS+GVI++ +L+ P VK EKQV Sbjct: 329 EIQRLKGRSQVEKENSSGYGKEVDLWSLGVIMFLLLSGNSPSFADGVK---EKQV----D 381 Query: 247 FRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGM-DSRLAKL 295 FR V +S + K+ ++ L++ P R T + W SRL KL Sbjct: 382 FRDPVWKSVSRQAKDLISNLLKTNPPDRFTVKQCLSHPWFARHSSRLTKL 431 >SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schizosaccharomyces pombe|chr 3|||Manual Length = 576 Score = 142 bits (345), Expect = 5e-35 Identities = 82/266 (30%), Positives = 141/266 (53%), Gaps = 11/266 (4%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 +I+ + +GEGS+ KV ATH + + +A K I + + + RE+ L + Sbjct: 34 YIIRETLGEGSFGKVKLATHYKTQQK---VALKFISRQLLKKSDMHMRVEREISYLKLLR 90 Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 HPHI+ + ++ + + +A G+L D++ + + E++ R + +QII ++Y H Sbjct: 91 HPHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHR 149 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203 I HRDLK EN+L+ N NVKI DFG + N+ D + L +T CGS +YAAPEV+ G Sbjct: 150 HKIVHRDLKPENLLLDDNLNVKIADFGLS-NI-MTDGNFL-KTSCGSPNYAAPEVINGKL 206 Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263 Y D+WS G++LY ML LPF++ + L++K + + + LS + + Sbjct: 207 YAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVY----VMPDFLSPGAQSLI 262 Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMD 289 +++ +P R T + W ++ Sbjct: 263 RRMIVADPMQRITIQEIRRDPWFNVN 288 >SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |Schizosaccharomyces pombe|chr 1|||Manual Length = 672 Score = 138 bits (334), Expect = 1e-33 Identities = 74/237 (31%), Positives = 129/237 (54%), Gaps = 11/237 (4%) Query: 8 DLSTTQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDY 67 DL T + + + +E V+GEGS+ KVY A H++ T KV+ + + Sbjct: 15 DLIATICNPRISDVGTYRIESVVGEGSFGKVYLAAHLLTNT-------KVVLKSSCRKQA 67 Query: 68 LTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQS 127 + L RE+ R+ HP+I + + + ++ + + NG+L D++ + + E + Sbjct: 68 I--ILAREIHHHRRLLHPNITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKTT 125 Query: 128 RLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETY 187 M Q+ +QY+H HRDLK EN+ + YNVK+ DFGF+R+ R T Sbjct: 126 CRIMWQLCCAIQYLHRQGCVHRDLKLENIFLDKAYNVKLGDFGFSRD-SDCSRRTFMNTR 184 Query: 188 CGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRK 244 CG+++Y APE+++G Y+ + D+WS+G+I+Y +L LPF+E V L E++++ + Sbjct: 185 CGTVAYCAPELVQGHKYIGECVDIWSLGIIMYALLIGRLPFDEDDV-SLTEQKIINE 240 >SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Schizosaccharomyces pombe|chr 2|||Manual Length = 423 Score = 133 bits (322), Expect = 3e-32 Identities = 85/272 (31%), Positives = 140/272 (51%), Gaps = 12/272 (4%) Query: 20 QEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVL 79 Q +I++K IG GS KV +++ + A K+I + + RE + Sbjct: 49 QVGNWIIKKTIGAGSMGKVKLVVNILTGEK---AALKMIPFTPNNTSQTVR-VQREALLG 104 Query: 80 IRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQ 139 + HP+I V + + A +I + G LL+++ G + E+ +R + Q+I+ L Sbjct: 105 RLLRHPNICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALV 164 Query: 140 YIHTMNIAHRDLKCENVLVTANYN-VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEV 198 Y+H I HRDLK ENVL+T + VK+ DFG + N +D D+L TYCGSL +AAPE+ Sbjct: 165 YLHKNFIVHRDLKIENVLLTQDSRQVKLIDFGLS-NFYSKD-DLL-RTYCGSLYFAAPEL 221 Query: 199 LKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258 L PY+ D+WS+GV++Y M+ +PF++ SV L+ K K F + +S + Sbjct: 222 LDAKPYIGPEVDVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEF----PSYISED 277 Query: 259 CKEQVTQLMEPEPKSRPTASAVFNGTWIGMDS 290 C + ++ P+ R + W+ +S Sbjct: 278 CCSLIAAMLNVNPRKRCSLEQAAKFPWLKKNS 309 >SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|chr 1|||Manual Length = 683 Score = 128 bits (310), Expect = 9e-31 Identities = 77/248 (31%), Positives = 125/248 (50%), Gaps = 9/248 (3%) Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIVH 89 IGEG +A+ ++ V + +I A KVI D L E+ V ++HP+IV Sbjct: 47 IGEGGFARCFR----VKDNYGNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQSMSHPNIVG 102 Query: 90 VSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHR 149 + F+ ++ L E+ L++ L + + E + R M QI+ L+Y+H + HR Sbjct: 103 FIDCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIHR 162 Query: 150 DLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKL- 208 DLK N+++ + NVKI DFG A + D + T CG+ +Y APE+L Sbjct: 163 DLKLGNIMLDESNNVKIGDFGLAALL--MDDEERKMTICGTPNYIAPEILFNSKEGHSFE 220 Query: 209 ADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLME 268 D+WS GV++Y +L PF + VK +Y K + F + V +S E K+ ++ L+ Sbjct: 221 VDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNV--DISAEAKDLISSLLT 278 Query: 269 PEPKSRPT 276 +P RP+ Sbjct: 279 HDPSIRPS 286 >SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase Ppk21|Schizosaccharomyces pombe|chr 2|||Manual Length = 550 Score = 125 bits (302), Expect = 8e-30 Identities = 70/222 (31%), Positives = 122/222 (54%), Gaps = 10/222 (4%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 ++ +IG+GS++KV +AT D+ A KV+D ++ K++ E D ++R+N Sbjct: 54 YVFGDIIGDGSFSKVRRAT---DKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMRLN 110 Query: 84 -HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142 P I + + FQ K + L A NG+LL ++ + + EN R + +I+S ++Y+H Sbjct: 111 GFPGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMH 170 Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFA-----RNVRQRDRDVLSETYCGSLSYAAPE 197 + I HRDLK EN+L N +VKITDFG A + V D ++ G+ Y APE Sbjct: 171 SCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPE 230 Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEK 239 +L + K +D+W+ ++Y M+ + PF+ ++ +++K Sbjct: 231 LLSR-QVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKK 271 >SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizosaccharomyces pombe|chr 3|||Manual Length = 569 Score = 125 bits (301), Expect = 1e-29 Identities = 75/252 (29%), Positives = 132/252 (52%), Gaps = 12/252 (4%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 F L KV+G+GS+ KV + D +R I A K + A E VL ++N Sbjct: 230 FELLKVVGKGSFGKVMQVRKR-DTSR--IYALKTMKKAHIVSRSEVDHTLAERTVLAQVN 286 Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 +P IV + FQ K ++ L F G+L L + G +++ ++ +++ L+ +H Sbjct: 287 NPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHE 346 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFAR-NVRQRDRDVLSETYCGSLSYAAPEVLKGV 202 N+ +RDLK EN+L+ ++ + DFG + N+ + DR + T+CG+ Y APE+L G Sbjct: 347 FNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDR---TNTFCGTPEYLAPELLLGH 403 Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262 Y K+ D W++GV+LY M+ PF + ++ ++Y K + RF + + + K+ Sbjct: 404 GY-TKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRF----PDNIDEKAKDL 458 Query: 263 VTQLMEPEPKSR 274 ++ L+ P+ R Sbjct: 459 LSGLLTRAPEKR 470 >SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 124 bits (298), Expect = 3e-29 Identities = 75/258 (29%), Positives = 134/258 (51%), Gaps = 18/258 (6%) Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85 L K +G GS + V A H + A K+I P Y + + E+ ++ + HP Sbjct: 14 LGKTLGTGSTSCVRLAKHA---KTGDLAAIKII-----PIRYAS--IGMEILMMRLLRHP 63 Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145 +I+ + +++ ++ L + +G+L ++ ++G + E ++ ++ QI+ + + H Sbjct: 64 NILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCHRFR 123 Query: 146 IAHRDLKCENVLVTAN-YNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPY 204 HRDLK EN+L+ N +KI DFG A D E YCGSL Y APE++ PY Sbjct: 124 FRHRDLKLENILIKVNEQQIKIADFGMAT---VEPNDSCLENYCGSLHYLAPEIVSHKPY 180 Query: 205 MPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVT 264 AD+WS GVILY++L+ LPF + +Y K +R + + + +S+ ++ + Sbjct: 181 RGAPADVWSCGVILYSLLSNKLPFGGQNTDVIYNK--IRHGAY--DLPSSISSAAQDLLH 236 Query: 265 QLMEPEPKSRPTASAVFN 282 ++++ P +R T VF+ Sbjct: 237 RMLDVNPSTRITIPEVFS 254 >SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase Cmk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 335 Score = 122 bits (295), Expect = 6e-29 Identities = 79/256 (30%), Positives = 133/256 (51%), Gaps = 12/256 (4%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN--HP 85 +V+G G+YA V +A H+ ET + + A K+++ K + F+ E+ +L R++ HP Sbjct: 35 RVLGGGTYATVREAVHI--ET-NKMYAAKIMN--KKMMEKKQDFVKNEIAILKRVSYEHP 89 Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145 +I+H+ + F+ ++ A G+L D + G+ E + MR S ++Y+H Sbjct: 90 NILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDNG 149 Query: 146 IAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202 I HRDLK EN+L + N ++ I DFG + +L T CG+ Y APEV + Sbjct: 150 IVHRDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLM-TACGTPEYMAPEVFRRT 208 Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262 Y K DMW+IGVI Y +L+ PF S ++ E + ++ F + +S K+ Sbjct: 209 GY-GKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGISETAKDF 267 Query: 263 VTQLMEPEPKSRPTAS 278 + + +E +P R TA+ Sbjct: 268 IKKCLENDPSKRLTAA 283 >SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizosaccharomyces pombe|chr 1|||Manual Length = 532 Score = 122 bits (294), Expect = 8e-29 Identities = 78/266 (29%), Positives = 135/266 (50%), Gaps = 11/266 (4%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 ++L + +G+G+ AKV H +T + V + +D K L RE+ +L +++ Sbjct: 23 WLLGRTLGQGNLAKVKLGKHF--QTNEKVALKMVYNDELEDKD-TWKRLQREVTILRQLH 79 Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 HP+I+ + +F R KY + + DL + ++ + E +R RQI+ + Y H Sbjct: 80 HPNIITLYQVF-RVPKYTVLALEYMDTDLHSMVVKHNRLDECTTRKIFRQIVHAIDYCHL 138 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203 +AHRDLK EN+L+ + VK+TDFG + + D LS T CG+ YAAPEV++G Sbjct: 139 HRVAHRDLKLENILLNKDLVVKLTDFGLSNFM--LDGSFLS-TSCGTPHYAAPEVIQGRY 195 Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263 Y D+W G++LY ML PF + ++ + + R + T+ + +S+ + + Sbjct: 196 YDGCDVDVWGCGILLYLMLVGEFPFEDVTISNV----LSRVCKGIYTIPSFVSSSASDLI 251 Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMD 289 Q++ P SR + + W D Sbjct: 252 RQMLMVLPTSRIKVAEIMQHPWFIAD 277 >SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1023 Score = 120 bits (290), Expect = 2e-28 Identities = 86/284 (30%), Positives = 140/284 (49%), Gaps = 22/284 (7%) Query: 24 FILEKVIGEGSYAKVYKATHM--VDETRHSIMACKVIDTAKAPRDYL-TKFLPRELDVLI 80 +IL + IG G + KV + + T H VI + + T L RE+ +L Sbjct: 492 YILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNCQTSRLMREVAILK 551 Query: 81 RI--NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138 + NHPHIV + + + + I L + G+L D++ + ++ + Q+ISG+ Sbjct: 552 GLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLISGV 611 Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFGFA----------RNVRQRDRDVLSETYC 188 Y+H+ + HRDLK EN+L+ N N+ I DFGFA + ++ L T C Sbjct: 612 AYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTFGHFNTLSEHSLPTEKPDLFSTSC 671 Query: 189 GSLSYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWR 246 GS YAAPE++ K Y AD+WS GVILY ML LPF++ E V R +R Sbjct: 672 GSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPFDDDPHNPNGE-NVPRLYR 730 Query: 247 F--RTTVV--NQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286 + T ++ ++ ++ + +++ P+P R SA+ N ++ Sbjct: 731 YICSTPLIFPEFFKSKARDILKKILVPDPAKRVRMSAIMNHAYL 774 >SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosaccharomyces pombe|chr 3|||Manual Length = 355 Score = 119 bits (286), Expect = 7e-28 Identities = 66/263 (25%), Positives = 136/263 (51%), Gaps = 11/263 (4%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 F + K +G+G + +VY A ++ I+A K + ++ + + K + RE+++ + Sbjct: 89 FEIGKPLGKGKFGRVYLAK---EKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLR 145 Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 H +I+ + F + ++ L FA G+L L + E + ++ Q+ + L Y+H Sbjct: 146 HKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHK 205 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203 ++ HRD+K EN+L+ + +K++DFG++ + R T CG+L Y PE+++G Sbjct: 206 KHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRR----TTLCGTLDYLPPEMVEGKE 261 Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263 + K+ D+WS+GV+ Y L A PF + S K++ + + + + + ++ + Sbjct: 262 HTEKV-DLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIA---KVDLKIPSFVPPDARDLI 317 Query: 264 TQLMEPEPKSRPTASAVFNGTWI 286 ++L++ P+ R + V WI Sbjct: 318 SRLLQHNPEKRMSLEQVMRHPWI 340 >SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 118 bits (284), Expect = 1e-27 Identities = 55/165 (33%), Positives = 102/165 (61%), Gaps = 3/165 (1%) Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134 EL +L I HP+++ + ++ + + F+ + + G+L D + + G+ E + ++ QI Sbjct: 58 ELVLLRLIEHPNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQI 117 Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYA 194 + GL+Y H ++I HRDLK EN+ + A+ ++KI +FG A +++Q + L +T CGS YA Sbjct: 118 LCGLEYCHKLHICHRDLKPENLYLDAHGSIKIGEFGMA-SIQQPGK--LLQTSCGSPHYA 174 Query: 195 APEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEK 239 +PE++ G Y +D+WS G+I + +L LPF++ +++ L K Sbjct: 175 SPEIIMGRSYDGCASDIWSCGIIFFALLTGKLPFDDDNIRSLLLK 219 >SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalytic subunit Pka1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 512 Score = 117 bits (282), Expect = 2e-27 Identities = 74/228 (32%), Positives = 116/228 (50%), Gaps = 12/228 (5%) Query: 12 TQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIM-ACKVIDTAKAPRDYLTK 70 T D +Q+ F+ + +G GS+ +V H+V + + A KV++ K + Sbjct: 191 TTKDRYGIQDFNFL--QTLGTGSFGRV----HLVQSNHNRLYYAIKVLEKKKIVDMKQIE 244 Query: 71 FLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLW 130 E +L R+ HP I + FQ F+ + FAE G+L L + PE ++ + Sbjct: 245 HTCDERYILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFY 304 Query: 131 MRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGS 190 ++I L Y+H I +RDLK EN+L+ ++KI DFGFA+ V + T CG+ Sbjct: 305 AAEVILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSN----CCTLCGT 360 Query: 191 LSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYE 238 Y APE++ PY K AD WS+G++++ ML PF + KLYE Sbjct: 361 PDYLAPEIISLKPY-NKAADWWSLGILIFEMLAGYPPFYSENPMKLYE 407 >SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosaccharomyces pombe|chr 1|||Manual Length = 636 Score = 111 bits (267), Expect = 1e-25 Identities = 74/272 (27%), Positives = 131/272 (48%), Gaps = 14/272 (5%) Query: 27 EKVIGEGSYAKVYKATHMVDETR---HSIMACKVI--DTAKAPRDYLTKFLPRELDVLIR 81 ++VIG G++ V + H VD ++ A K A++ + Y TK L E + Sbjct: 354 QEVIGRGAFG-VVRIAHKVDPQNSGSETLYAVKEFRRKPAESQKKY-TKRLTSEFCISSS 411 Query: 82 INHPHIVHVSNIFQR-RAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140 + HP+++H ++ Q + Y + GDL + G + ++ + +Q++ G+ Y Sbjct: 412 LRHPNVIHTLDLIQDGKGDYCEVMELCSGGDLYTLIMAAGRLEPMEADCFFKQLMRGVDY 471 Query: 141 IHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQR-DRDV-LSETYCGSLSYAAPEV 198 +H M +AHRDLK EN+L+T + ++KITDFG R +++ ++ CGS Y APE Sbjct: 472 LHDMGVAHRDLKPENLLLTVSGSLKITDFGNGECFRMAWEKEAHMTCGLCGSAPYIAPEE 531 Query: 199 LKGVPYMPKLADMWSIGVILYTMLNKALPFN--ETSVKKLYEKQVM-RKWRFRTTVVNQL 255 + P+ D+W+ GVI M + + S + Y + +M RK + L Sbjct: 532 YTESEFDPRAVDVWACGVIYMAMRTGRHLWRVAKKSEDEYYSRYLMDRKNESGYEPIEML 591 Query: 256 S-TECKEQVTQLMEPEPKSRPTASAVFNGTWI 286 + C+ + ++ P P R TA + W+ Sbjct: 592 ERSRCRNTLYNILHPNPTYRLTAKQIMKSEWV 623 >SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1401 Score = 111 bits (267), Expect = 1e-25 Identities = 77/291 (26%), Positives = 138/291 (47%), Gaps = 15/291 (5%) Query: 5 DKIDLSTTQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP 64 D I L+++ S+I + ++G + G + VY +M ++ K+ D+ + Sbjct: 1022 DFIKLASSFSNITIRWQQGHFVRS----GMFGDVYTGVNMETGDLLAVKEIKLQDS-RTF 1076 Query: 65 RDYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPE 124 R + + + E+ VL R+NHP++V + R K +IF+ F + G L D L E Sbjct: 1077 RSTVDQ-IHNEMTVLERLNHPNVVTYYGVEVHREKVYIFMEFCQGGSLADLLAHGRIEDE 1135 Query: 125 NQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFA--------RNVR 176 N ++++ Q++ GL YIH+ +I HRD+K N+L+ +K +DFG A VR Sbjct: 1136 NVLKVYVVQLLEGLAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEVR 1195 Query: 177 QRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLA-DMWSIGVILYTMLNKALPFNETSVKK 235 D + G+ Y APE++ G A D+WS+G ++ M+ + P++E + Sbjct: 1196 YEDIQPELQHLAGTPMYMAPEIILGTKKGDFGAMDIWSLGCVILEMMTGSTPWSEMDNEW 1255 Query: 236 LYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286 V ++S+ ++ + Q E +P+ RP A + WI Sbjct: 1256 AIMYHVAAMHTPSIPQNEKISSLARDFIEQCFERDPEQRPRAVDLLTHPWI 1306 >SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces pombe|chr 3|||Manual Length = 496 Score = 111 bits (266), Expect = 2e-25 Identities = 66/207 (31%), Positives = 107/207 (51%), Gaps = 9/207 (4%) Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 H +I+H N + ++ L FA+ GDL D + + I E+ ++ + Q++ G+ ++H+ Sbjct: 71 HKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFMHS 130 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203 +AHRDLK EN+L+ N N+KI+DFGFA + + L + GS YAAPE+ + Sbjct: 131 KGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEITQ--Q 188 Query: 204 YMPKLADMWSIGVILYTMLNKALPFNE----TSVKKLYEKQVMRKWRFRTTVVNQLSTEC 259 Y D+WS G+IL+ +L P++E T LY+KQ R N LS Sbjct: 189 YDGSKVDVWSCGIILFALLLGNTPWDEAISNTGDYLLYKKQCERP---SYHPWNLLSPGA 245 Query: 260 KEQVTQLMEPEPKSRPTASAVFNGTWI 286 +T ++ +P R + V W+ Sbjct: 246 YSIITGMLRSDPFKRYSVKHVVQHPWL 272 >SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc7|Schizosaccharomyces pombe|chr 2|||Manual Length = 1062 Score = 109 bits (262), Expect = 6e-25 Identities = 69/278 (24%), Positives = 129/278 (46%), Gaps = 12/278 (4%) Query: 19 LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDV 78 +Q L +G+G++ VY+ ++ + +A K + +K + L+ + E+D+ Sbjct: 4 IQASSITLGDCLGKGAFGAVYRGLNIKNG---ETVAVKKVKLSKMLKSDLS-VIKMEIDL 59 Query: 79 LIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138 L ++HP+IV +Q I L + ENG L G IPEN L+ Q++ GL Sbjct: 60 LKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGL 119 Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEV 198 Y+H + HRD+K N+L T + +K+ DFG A + + + GS + APEV Sbjct: 120 LYLHNQGVIHRDIKGANILTTKDGTIKLADFGVATKINALE----DHSVVGSPYWMAPEV 175 Query: 199 LKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258 ++ V +D+WS+G + +L+ P+ + + V + + + +S+ Sbjct: 176 IELVG-ATTASDIWSVGCTVIELLDGNPPYYDLDPTSALFRMVKDE---HPPLPSNISSA 231 Query: 259 CKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLT 296 K + Q + +P R + W+ M+ +K + Sbjct: 232 AKSFLMQCFQKDPNLRIKTRKLLKHPWVIMNQTSSKFS 269 >SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosaccharomyces pombe|chr 1|||Manual Length = 696 Score = 109 bits (261), Expect = 8e-25 Identities = 74/259 (28%), Positives = 125/259 (48%), Gaps = 11/259 (4%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 F ++IG+G++ +VY D R I A K I R E ++L+R + Sbjct: 302 FTALRLIGKGTFGQVY-LVRKNDTNR--IYAMKKISKKLIVRKKEVTHTLGERNILVRTS 358 Query: 84 ---HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140 P IV + FQ + ++ + G+L L G PE +++ ++ +++ L++ Sbjct: 359 LDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEH 418 Query: 141 IHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200 +H +I +RDLK EN+L+ A+ ++ + DFG ++ + + T+CG+ Y APEVL Sbjct: 419 LHKHDIIYRDLKPENILLDADGHIALCDFGLSK--ANLSANATTNTFCGTTEYLAPEVLL 476 Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECK 260 K D WS+GV+++ M PF V+++Y K RF V LS+E + Sbjct: 477 EDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGV---LSSEGR 533 Query: 261 EQVTQLMEPEPKSRPTASA 279 V L+ P R A A Sbjct: 534 SFVRGLLNRNPNHRLGAVA 552 >SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizosaccharomyces pombe|chr 1|||Manual Length = 646 Score = 109 bits (261), Expect = 8e-25 Identities = 71/254 (27%), Positives = 123/254 (48%), Gaps = 11/254 (4%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 F+ K+IG+G++ +VY D R + A KV+ R E D+L++ + Sbjct: 266 FVPLKLIGKGTFGQVY-LVRKKDTER--VYAMKVLSKKVIVRRKEVAHTVGERDILVQTS 322 Query: 84 ---HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140 P IV + FQ ++ + G+L L ++ PE +++ ++ +++ LQ Sbjct: 323 AADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQA 382 Query: 141 IHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200 +H I +RDLK EN+L+ ++ + DFG ++ + T+CG+ Y APEV+ Sbjct: 383 LHKRGIVYRDLKPENILLDVQGHIALCDFGLSK--ANLSVGTTTRTFCGTTDYLAPEVIL 440 Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECK 260 + D WS+GV+LY M PF + ++LY+ V K RF + LS E + Sbjct: 441 DEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGL---LSVEAR 497 Query: 261 EQVTQLMEPEPKSR 274 + + L+ PK R Sbjct: 498 DLIKLLLNRNPKHR 511 >SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 436 Score = 104 bits (250), Expect = 2e-23 Identities = 65/247 (26%), Positives = 121/247 (48%), Gaps = 12/247 (4%) Query: 29 VIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRINHPHI 87 V+G GSY KV + + A K + A R + E +L + HP I Sbjct: 96 VLGRGSYGKVLLVKQ---KNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRHPFI 152 Query: 88 VHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIA 147 + FQ + ++ L++A G+L L + +PE+ + ++ L ++H + I Sbjct: 153 CRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKLGIV 212 Query: 148 HRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPK 207 +RDLK EN L+ A ++ +TDFG ++ V + D S + G+ Y APE+L PY Sbjct: 213 YRDLKPENCLLDAEGHILLTDFGLSK-VAENGADCRS--FVGTEEYCAPEILLEQPY-DH 268 Query: 208 LADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLM 267 D WS+G++++ +L + PF + K++ EK R + + ++++ ++ + + + Sbjct: 269 AVDWWSMGILIFDLLTGSPPFTANNHKRIMEKIT----RAKPNIPFYVTSDARDIINKFL 324 Query: 268 EPEPKSR 274 + PK R Sbjct: 325 KKNPKQR 331 >SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces pombe|chr 1|||Manual Length = 312 Score = 101 bits (243), Expect = 1e-22 Identities = 72/251 (28%), Positives = 125/251 (49%), Gaps = 12/251 (4%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHI 87 ++IG+GS+ V++A D I+A KV+D A +D + + L +E++ LI +N HI Sbjct: 10 QLIGQGSFGSVFRAQ---DVESSKIVALKVVDL-DATKDQI-ETLTQEINFLIDLNSVHI 64 Query: 88 VHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIA 147 F + +I + + + G LD L +G E MRQ++ L Y+H Sbjct: 65 TKYYASFVDGFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQGKM 124 Query: 148 HRDLKCENVLVTANYNVKITDFGFARNVRQ-RDRDVLSETYCGSLSYAAPEVLKGVPYMP 206 HRD+K N+L + VK+ DFG + + RD+ ++ + G+ + APEV+K Y Sbjct: 125 HRDIKAANILTMKDGLVKLADFGVSGQLESLRDK---NDDFVGTPFWMAPEVVKQTGYNY 181 Query: 207 KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQL 266 K AD+WS+G+ Y + P++ K+ ++ K + ++ S + V+ Sbjct: 182 K-ADIWSLGITAYELATGEPPYSGIHPMKVL--LLIPKHSPPSLERSKFSRAFCDFVSNC 238 Query: 267 MEPEPKSRPTA 277 ++ PK R TA Sbjct: 239 LKKNPKDRATA 249 >SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase Ppk6|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 101 bits (243), Expect = 1e-22 Identities = 61/210 (29%), Positives = 116/210 (55%), Gaps = 15/210 (7%) Query: 28 KVIGEGSYAKVYKATHMVDETRH----SIMACKVI-DTAKAPRDYLTKFLPRELDVLIRI 82 K +G G+Y +V AT+ ++ SI +++ D+ +D T +P E+ +L + Sbjct: 507 KELGIGAYGQVKLATYKSNKVHEVILKSISKSRILLDSWMRDKDLGT--VPMEISILHFL 564 Query: 83 ---NHPHIVHVSNIFQRRAKYFIFLRFAENG-DLLDFLTQNGAIPENQSRLWMRQIISGL 138 +HP+IV + F+ Y++ + G DL D++ +I E +S+ QI + Sbjct: 565 KAHSHPNIVKMITFFEDNENYYLLTEPQKPGIDLFDYIELKPSISEKESKAIFFQIALAV 624 Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEV 198 ++H+ +I HRD+K ENV++ N ++ DFG + + D T+ G++ +AAPE+ Sbjct: 625 AHLHSFDIIHRDIKDENVILEGNGCARLIDFGSSSLTKNGPFD----TFRGTVGFAAPEL 680 Query: 199 LKGVPYMPKLADMWSIGVILYTMLNKALPF 228 L+G Y+ K D+W++G++LYT++ + P+ Sbjct: 681 LRGEKYLGKEQDIWALGILLYTIVYRENPY 710 >SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizosaccharomyces pombe|chr 1|||Manual Length = 513 Score = 101 bits (241), Expect = 2e-22 Identities = 74/271 (27%), Positives = 130/271 (47%), Gaps = 18/271 (6%) Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKV----IDTAKAPRDYLTKFLPRELDVLIR 81 L VIGEG+ + + D + I KV +DT+ R Y+ F+ E Sbjct: 243 LNNVIGEGASSFIRVIN---DRNKLPIYVAKVFRPPLDTSLLRR-YVRYFIA-EYTFAST 297 Query: 82 INHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141 + HP+I+ V +I +R + + DL F+T+ +++ Q++ G+ Y+ Sbjct: 298 LRHPNIIKVLDIIYKRHTILQIIEYVPY-DLFTFITKGHCSALKADQMFF-QLLDGVAYM 355 Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFG--FARNVRQRDRDVLSETYCGSLSYAAPEVL 199 H++ IAHRD+K +N+++ N NVKI DFG F + ++S+ GS Y APEVL Sbjct: 356 HSLGIAHRDIKLDNIMLDENLNVKIIDFGTAFVFHYPFESTTLMSDGVVGSKPYVAPEVL 415 Query: 200 KGVPYMPKLADMWSIGVILYTMLNKALPFN--ETSVKK--LYEKQVMRKWRFRTTVVNQL 255 PY P D+WS ++ + K P+ TS K+ LY Q ++ ++ L Sbjct: 416 TQKPYDPSAVDVWSCAIVYCCIALKRFPWKVPHTSDKRFNLYVTQ-RNDPNTKSQLIESL 474 Query: 256 STECKEQVTQLMEPEPKSRPTASAVFNGTWI 286 ++ + +++ + +R + S + TW+ Sbjct: 475 PMNSRDTIYHMLDIDFNTRCSISGARSTTWM 505 >SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosaccharomyces pombe|chr 3|||Manual Length = 592 Score = 101 bits (241), Expect = 2e-22 Identities = 72/270 (26%), Positives = 125/270 (46%), Gaps = 21/270 (7%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVL-IRI 82 F +++GEGSY+ V AT + ++I KV+D ++ K++ E + L I Sbjct: 99 FKFGEILGEGSYSTVLTATENSTKREYAI---KVLDKRHIIKEKKEKYVNIEKEALCILS 155 Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142 HP + + FQ + L A NG+LLD++ + G E ++ + I+ + Y+H Sbjct: 156 KHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMH 215 Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFAR-----------NVRQRDR-DVLSETYCGS 190 + HRDLK EN+L+ N KITDFG A+ + D+ S ++ G+ Sbjct: 216 GRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGT 275 Query: 191 LSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTT 250 Y +PEVL +D+W+ G IL+ ML PF + ++ + + Sbjct: 276 ARYVSPEVLSD-KIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYE---- 330 Query: 251 VVNQLSTECKEQVTQLMEPEPKSRPTASAV 280 + +S + + +L+ +PK R T + Sbjct: 331 IPPDISDVASDLIKKLLVLDPKDRLTVDEI 360 >SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|Schizosaccharomyces pombe|chr 3|||Manual Length = 288 Score = 99.5 bits (237), Expect = 6e-22 Identities = 62/198 (31%), Positives = 102/198 (51%), Gaps = 10/198 (5%) Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85 LEK +GEG+YA VYK + V I+A KVI T RE+ ++ + HP Sbjct: 6 LEK-LGEGTYAHVYKGQNRVTG---EIVALKVIRIDADEGTPSTAI--REISLMKELRHP 59 Query: 86 HIVHVSNIFQRRAKYFIFLRFAENG--DLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 +I+ +S++ Q K + + E +D GA+P +Q + + +Q++ G+ + H Sbjct: 60 NIMSLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHE 119 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203 + HRDLK +N+L+ + +K+ DFG AR++ +E +L Y AP+VL G Sbjct: 120 NRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNEVV--TLWYRAPDVLLGSR 177 Query: 204 YMPKLADMWSIGVILYTM 221 D+WS+G I+ M Sbjct: 178 VYSTSIDIWSVGCIMAEM 195 >SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2|Schizosaccharomyces pombe|chr 2|||Manual Length = 659 Score = 99.1 bits (236), Expect = 8e-22 Identities = 67/234 (28%), Positives = 113/234 (48%), Gaps = 19/234 (8%) Query: 10 STTQSDIAVLQEKG------FILEKVIGEGSYAKVYKATHMVDETRHSIMACK--VIDTA 61 STT D L+E +I +IG GS+ +VY ++ + +MA K ++D+ Sbjct: 374 STTSEDTNTLEEDTDDQSIKWIRGALIGSGSFGQVYLG---MNASSGELMAVKQVILDSV 430 Query: 62 KAPRDYLTKFLPR---ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQ 118 +D K L E+ +L ++H HIV IFL + G + LT Sbjct: 431 SESKDRHAKLLDALAGEIALLQELSHEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTM 490 Query: 119 NGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQR 178 G+ E + +++Q + GL+Y+H+ I HRD+K N+LV +KI+DFG ++ + Sbjct: 491 YGSFEETLVKNFIKQTLKGLEYLHSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELN 550 Query: 179 DRDVLS----ETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPF 228 + ++ GS + APEV+K + K D+WS+G ++ ML P+ Sbjct: 551 STSTKTGGARPSFQGSSFWMAPEVVKQTMHTEK-TDIWSLGCLVIEMLTSKHPY 603 >SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 1116 Score = 99.1 bits (236), Expect = 8e-22 Identities = 76/290 (26%), Positives = 139/290 (47%), Gaps = 16/290 (5%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTK----FLPRELDVLIRIN 83 ++IG G+Y KV+ A ++ ++ ++ T D L K + E+ ++ ++ Sbjct: 829 ELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISMIADLD 888 Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 H +IV + IFL + G + L G E R RQ++ GL Y+H+ Sbjct: 889 HLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRFVSRQVLYGLSYLHS 948 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFAR---NVRQRDRDVLSETYCGSLSYAAPEVLK 200 I HRDLK +N+L+ + KI+DFG ++ NV D ++ + GS+ + APEV+ Sbjct: 949 KGIIHRDLKADNLLIDFDGVCKISDFGISKHSDNVYDNDANLSMQ---GSIFWMAPEVIH 1005 Query: 201 G--VPYMPKLADMWSIGVILYTMLNKALPFN-ETSVKKLYEKQVMRKW-RFRTTVVNQLS 256 Y K+ D+WS+G ++ ML P++ + +++ +++ +K + +V+Q+S Sbjct: 1006 NDHQGYSAKV-DVWSLGCVVLEMLAGRRPWSTDEAIQAMFKLGTEKKAPPIPSELVSQVS 1064 Query: 257 TECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRL-AKLTFLEESLLKQ 305 E + + RPTA + N ++ D K T L + L K+ Sbjct: 1065 PEAIQFLNACFTVNADVRPTAEELLNHPFMKCDEEFNFKDTNLYDMLCKR 1114 >SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharomyces pombe|chr 2|||Manual Length = 1016 Score = 98.7 bits (235), Expect = 1e-21 Identities = 56/215 (26%), Positives = 105/215 (48%), Gaps = 4/215 (1%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 F V+G+G++ KV A ++ ++I K + TK R V R Sbjct: 683 FTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVANRER 742 Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 HP +V++ + FQ + + + F GDL+ + Q +++ + ++ L+Y H Sbjct: 743 HPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQE-QFSRRRAQFYAAEVCLALKYFHD 801 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203 I +RDLK +N+L++ + +VK+ D+G + D + T+CG+ + APE+L Sbjct: 802 NGIIYRDLKLDNILLSPDGHVKVADYGLCKEDMWHDN--TTATFCGTPEFMAPEILLEQQ 859 Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYE 238 Y + D W+ GV++Y ML PF +++++ Sbjct: 860 Y-TRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFD 893 >SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 658 Score = 93.9 bits (223), Expect = 3e-20 Identities = 69/275 (25%), Positives = 141/275 (51%), Gaps = 15/275 (5%) Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIVH 89 IG+G+ VY A + T S+ A K ++ + P+ +F+ E+ V+ +H +IV+ Sbjct: 392 IGQGASGDVYSARQV--GTNLSV-AIKKMNINQQPKK---EFIVNEILVMKSHHHKNIVN 445 Query: 90 VSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHR 149 + F +++ ++ + + G L + +T N + E Q ++ + GLQ++H I HR Sbjct: 446 FIDTFFYKSELWMVMEYMRGGSLTEVVTNN-TLSEGQIAAICKETLEGLQHLHENGIVHR 504 Query: 150 DLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSE-TYCGSLSYAAPEVLKGVPYMPKL 208 D+K +N+L++ ++K+TDFGF + D ++ T G+ + APEV+ Y K+ Sbjct: 505 DIKSDNILLSLQGDIKLTDFGFCAQI---DSNMTKRTTMVGTPYWMAPEVVTRKEYGFKV 561 Query: 209 ADMWSIGVILYTMLNKALPF-NETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLM 267 D+WS+G++ M+ P+ NE ++ LY + + + LS+ + +++ + Sbjct: 562 -DVWSLGIMAIEMVEGEPPYLNENPLRALYLIATIGTPKISRPEL--LSSVFHDFLSKSL 618 Query: 268 EPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESL 302 PK RP++ + ++ ++ L L +S+ Sbjct: 619 TVNPKQRPSSGELLRHPFLKQAVPVSSLIPLIKSI 653 >SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizosaccharomyces pombe|chr 3|||Manual Length = 338 Score = 93.9 bits (223), Expect = 3e-20 Identities = 64/209 (30%), Positives = 100/209 (47%), Gaps = 11/209 (5%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 F + VIG+GS++ V+ H + R A K I+ K + K L E+ +L +N Sbjct: 30 FKIRNVIGKGSWSTVFVVKHRQTKQR---FALKCINKKKHDEHKIKK-LRNEVLLLQSLN 85 Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 HP + + F+ K ++ GDL ++Q E+ R+WM +++S L YIH+ Sbjct: 86 HPLLCKFYSEFEDETKIYLVTDLMLGGDLRYHISQR-KFNESVIRIWMVELVSALIYIHS 144 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLS---YAAPEVL- 199 + HRD+K +N+L+ + K+ DF A V S G + Y APE L Sbjct: 145 KGVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPSKSNMTVGRVGTPVYMAPETLI 204 Query: 200 KGVPYMPKLADMWSIGVILYTMLNKALPF 228 V Y K +D WS+G+ Y L + PF Sbjct: 205 HAVSY--KESDWWSLGITFYECLFQVRPF 231 >SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 589 Score = 93.5 bits (222), Expect = 4e-20 Identities = 59/216 (27%), Positives = 109/216 (50%), Gaps = 7/216 (3%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 F ++ +G+G+ VY A +V + I I + + + E+ V+ Sbjct: 309 FNVKHKLGQGASGSVYLAK-VVGGKQLGIFDSVAIKSIDLQCQTRKELILNEITVMRESI 367 Query: 84 HPHIV-HVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142 HP+IV ++ + R ++ + + G L D + ++ +R+ + + G+Q++H Sbjct: 368 HPNIVTYLDSFLVRERHLWVVMEYMNAGSLTDIIEKSKLTEAQIARICL-ETCKGIQHLH 426 Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202 NI HRD+K +NVL+ + N+KITDFGF + R + T G+ + APEV+K Sbjct: 427 ARNIIHRDIKSDNVLLDNSGNIKITDFGFCARLSNRTNKRV--TMVGTPYWMAPEVVKQN 484 Query: 203 PYMPKLADMWSIGVILYTMLNKALPF-NETSVKKLY 237 Y K+ D+WS+G+++ M+ P+ E ++ LY Sbjct: 485 EYGTKV-DIWSLGIMIIEMIENEPPYLREDPIRALY 519 >SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schizosaccharomyces pombe|chr 2|||Manual Length = 470 Score = 91.9 bits (218), Expect = 1e-19 Identities = 59/188 (31%), Positives = 97/188 (51%), Gaps = 15/188 (7%) Query: 29 VIGEGSYAKVYKATHMVDETRHSIMA-CKVIDTAKAPRDYLTKFLPRELDVLIRIN-HPH 86 +IG G+Y VYKA + D T +++ A CK + K REL + R++ HP+ Sbjct: 23 IIGAGAYGVVYKAEDIYDGTLYAVKALCK-----DGLNEKQKKLQARELALHARVSSHPY 77 Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQS--RLWMRQIISGLQYIHTM 144 I+ + + + ++ L++ NGDL ++T+ N + Q+IS +++ H++ Sbjct: 78 IITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQLISAVEHCHSV 137 Query: 145 NIAHRDLKCENVLVTANYN-VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203 I HRDLK EN++V + N V + DFG A S+ CGSL Y +PE + V Sbjct: 138 GIYHRDLKPENIMVGNDVNTVYLADFGLATT-----EPYSSDFGCGSLFYMSPECQREVK 192 Query: 204 YMPKLADM 211 + L+DM Sbjct: 193 KLSSLSDM 200 >SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosaccharomyces pombe|chr 1|||Manual Length = 988 Score = 91.9 bits (218), Expect = 1e-19 Identities = 54/215 (25%), Positives = 104/215 (48%), Gaps = 4/215 (1%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 F V+G+G++ KV A + V++ ++I K K K +V + Sbjct: 664 FTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKHVFEVANKEK 723 Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 HP ++++ FQ + + + + GDL+ + Q ++R + ++ L+Y H Sbjct: 724 HPFLLNLFASFQTSTRVYFVMEYILGGDLMVHI-QRQQFSVKRARFYGAEVCLALKYFHE 782 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203 IA+RDLK +N+L+ + +++I D+G + + T+CG+ + APE+L Sbjct: 783 NGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGN--TTSTFCGTPEFMAPEILLEQQ 840 Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYE 238 Y K D W+ GV++Y ML PF +++++ Sbjct: 841 Y-SKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFD 874 >SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizosaccharomyces pombe|chr 2|||Manual Length = 461 Score = 91.5 bits (217), Expect = 2e-19 Identities = 80/296 (27%), Positives = 138/296 (46%), Gaps = 40/296 (13%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIM-ACKVIDTAKAPR----DYLTKFLPRELDVLIRI 82 K I +G+ + + TH T I A KV K + + FL RE + ++ Sbjct: 124 KSIAKGATSTIKVVTHRDKITDAKIYYAAKVYRKTKTSHKKRLNTMVYFL-REWSIQPKL 182 Query: 83 NHPHIVHV-------SNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQII 135 +HP+I+ V +++F + A + + + GDL + + E++ +++QI+ Sbjct: 183 DHPNILKVICPCVTLTSVFNKSAGFCLVQEYCPQGDLFKQIEEKVLTLEDKC-CYLKQIL 241 Query: 136 SGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNV-RQRDRDVLS--ETYCGSLS 192 + Y+ + IAHRDLK EN+L+ + +K+TDFG + V D + + GSL+ Sbjct: 242 QAVAYLQSQRIAHRDLKPENILIGRDGLLKLTDFGTSEIVGNPGDNESIRFVSGAVGSLA 301 Query: 193 YAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVK-KLYEKQVMR-------- 243 Y APE Y LAD WS G++L + PF +TSVK LY + M Sbjct: 302 YLAPEAFHENEYCGLLADRWSCGILLKVLFTGYFPF-KTSVKTDLYYSKYMSILTDTCGI 360 Query: 244 ----KWRFRTTVVNQLST---------ECKEQVTQLMEPEPKSRPTASAVFNGTWI 286 + F+T V+ Q+ T K+ + L+ P+ ++RP+ ++ W+ Sbjct: 361 SSTDESSFQTEVIKQIPTLQPLRYIPEGAKKIILSLLNPDSQNRPSLDSILGTAWV 416 >SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 474 Score = 90.6 bits (215), Expect = 3e-19 Identities = 97/358 (27%), Positives = 149/358 (41%), Gaps = 31/358 (8%) Query: 18 VLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELD 77 +LQ+KG+ +E+ + +GSY V A + R + + K +L + L Sbjct: 3 LLQKKGYKVERPLNKGSYGTVVLAHRLFRTPRCKDLKYAIKCIKKPAYTFLQEV--NILR 60 Query: 78 VLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNG-AIPENQSRLWMR---Q 133 L R H +I+H F+ Y++ L + GDL + + N +NQ + Q Sbjct: 61 QLSRSRHRNIIHFVESFEDNVYYYVVLEYCPLGDLYECILNNDFPNAKNQPEMIKNIFLQ 120 Query: 134 IISGLQYIHTMNIAHRDLKCENVLVTANYN-----VKITDFGFARNVRQRDRDVLSETY- 187 II G+ ++H+ I HRDLK EN L++ + + VKI+DFG A RD +S + Sbjct: 121 IIDGVAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLA------CRDKISYDFG 174 Query: 188 CGSLSYAAPEVLK---GVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRK 244 GS Y APE + G Y P+ AD+W++G+ L ++ PF K M Sbjct: 175 TGSDRYMAPEQFEEVDGAGYSPRAADIWALGICLLNLIFARNPFTYPHEKDPIFADYMLD 234 Query: 245 WRFRTTVVNQLSTECKE--QVTQLMEPEPKS-RPTASAVFNGT-WIGMDSRLAKLTFLEE 300 V LS + + + PE +S T AV T W D L EE Sbjct: 235 AMTLFDVFPTLSQDTYNVLRACLCVSPEKRSLAKTREAVLAVTKWTTDDEELESFVNEEE 294 Query: 301 SLLKQAHEESQKRDNSTEEDSEVERI------AELRRKGRGKEGLKVLKNVDANYAKS 352 ++ T+ D E R A ++G L L +VD N + S Sbjct: 295 EFRASDFMPAEDNVRCTQSDREPLRTPSVLTPANTIQRGLLPSKLPALSDVDENISTS 352 >SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 652 Score = 90.2 bits (214), Expect = 4e-19 Identities = 77/322 (23%), Positives = 149/322 (46%), Gaps = 26/322 (8%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVID-TAKAPR------DYLTKFLPRELDVLI 80 K +G G + KV D ++A K+I T + P+ + + RE+ +L Sbjct: 139 KELGRGMHGKVKLGR---DTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRREIAILK 195 Query: 81 RINHPHIVHVSNIFQ--RRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138 + HP++V + + K ++ L + G++ + + +++R + R ++ GL Sbjct: 196 KCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRDVVLGL 255 Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFG---FARNVRQRDRDVLSETYCGSLSYAA 195 +Y+H I HRD+K N+L+ ++ VKI+DFG A D DV G+ ++ A Sbjct: 256 EYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNEDNDVELAKTVGTPAFFA 315 Query: 196 PEVL-----KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTT 250 PE+ + P + + D+W++GV L+ +L PFN + +L++K V + +T Sbjct: 316 PELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPFNASMEYELFDKIVNERLNIPST 375 Query: 251 VVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLKQAHEES 310 + E ++ + +L+ +P+ R T V W +D +L+ + S Sbjct: 376 --PDIGEEGRDLLKRLLCKDPEQRITLVEVKLHPWT-LDGLKDPEKWLQNT---DPSTVS 429 Query: 311 QKRDNSTEEDSEVERIAELRRK 332 + ++ E S + + LRRK Sbjct: 430 RVEVSTDEVASAISLVGRLRRK 451 >SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 422 Score = 87.4 bits (207), Expect = 3e-18 Identities = 60/209 (28%), Positives = 103/209 (49%), Gaps = 10/209 (4%) Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80 E F + K +G+G+Y V A ++ + + ++ K+ + + LTK RE+ +LI Sbjct: 18 EPNFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFS--KSILTKRALREIKLLI 75 Query: 81 RI-NHPHIVHVSNIF----QRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQII 135 NH +I + ++ + +I+ E DL + + + + ++ QI+ Sbjct: 76 HFRNHRNITCIYDLDIINPYNFNEVYIYEELME-ADLNAIIKSGQPLTDAHFQSFIYQIL 134 Query: 136 SGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQ--RDRDVLSETYCGSLSY 193 GL+YIH+ N+ HRDLK N+LV A+ +KI DFG AR + + Y + Y Sbjct: 135 CGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGFMTEYVATRWY 194 Query: 194 AAPEVLKGVPYMPKLADMWSIGVILYTML 222 APE++ K D+WS+G IL +L Sbjct: 195 RAPEIMLSFSSYHKGIDVWSVGCILAELL 223 >SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccharomyces pombe|chr 2|||Manual Length = 605 Score = 86.2 bits (204), Expect = 6e-18 Identities = 73/264 (27%), Positives = 117/264 (44%), Gaps = 17/264 (6%) Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIVH 89 +G+G+Y VYKA H + MA K I + + + ELD+L + P+IV Sbjct: 326 LGKGNYGVVYKALH---QPTGVTMALKEIRLSLEEATFNQIIM--ELDILHKAVSPYIVD 380 Query: 90 VSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI-HTMNIAH 148 F FI + + + G + D L G E ++ GL+ + NI H Sbjct: 381 FYGAFFVEGSVFICMEYMDAGSM-DKLYAGGIKDEGVLARTAYAVVQGLKTLKEEHNIIH 439 Query: 149 RDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK------GV 202 RD+K NVLV +N VK+ DFG + N+ +S+T G SY APE ++ GV Sbjct: 440 RDVKPTNVLVNSNGQVKLCDFGVSGNLVAS----ISKTNIGCQSYMAPERIRVGGPTNGV 495 Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262 AD+WS+G+ + M A P+ S ++ + ++ + S E ++ Sbjct: 496 LTYTVQADVWSLGLTILEMALGAYPYPPESYTSIFAQLSAICDGDPPSLPDSFSPEARDF 555 Query: 263 VTQLMEPEPKSRPTASAVFNGTWI 286 V + + P RP + N W+ Sbjct: 556 VNKCLNKNPSLRPDYHELANHPWL 579 >SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosaccharomyces pombe|chr 3|||Manual Length = 877 Score = 86.2 bits (204), Expect = 6e-18 Identities = 76/273 (27%), Positives = 134/273 (49%), Gaps = 30/273 (10%) Query: 29 VIGEGSYAKVYKATHMVDET-RHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN-HPH 86 ++G G +++V++ V++T ++++ KV + R+ L + E+ + + H H Sbjct: 571 LLGSGEFSEVFQVEDPVEKTLKYAVKKLKVKFSGPKERNRLLQ----EVSIQRALKGHDH 626 Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPE-NQSRLW--MRQIISGLQYIHT 143 IV + + ++ ++ + ENG L FL + G + ++ R+W + ++ GLQ+IH Sbjct: 627 IVELMDSWEHGGFLYMQVELCENGSLDRFLEEQGQLSRLDEFRVWKILVEVALGLQFIHH 686 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203 N H DLK NV++T +KI DFG A +V R + E G Y APEVL Sbjct: 687 KNYVHLDLKPANVMITFEGTLKIGDFGMA-SVWPVPRGMERE---GDCEYIAPEVLANHL 742 Query: 204 YMPKLADMWSIGVILY-TMLNKALPFNETSVKKLYEKQVMRKWRFRTT-VVNQLSTECKE 261 Y K AD++S+G+ ++ N LP N S +KL + R +T + L++ +E Sbjct: 743 Y-DKPADIFSLGITVFEAAANIVLPDNGQSWQKLRSGDLSDAPRLSSTDNGSSLTSSSRE 801 Query: 262 Q--------------VTQLMEPEPKSRPTASAV 280 V ++ PEP++RPT + Sbjct: 802 TPANSIIGQGGLDRVVEWMLSPEPRNRPTIDQI 834 >SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Schizosaccharomyces pombe|chr 2|||Manual Length = 297 Score = 85.8 bits (203), Expect = 8e-18 Identities = 55/214 (25%), Positives = 107/214 (50%), Gaps = 7/214 (3%) Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIVH 89 IGEG+Y VYKA H + ++ ++ D ++ + + +V N + V Sbjct: 10 IGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDENNRSNCVR 69 Query: 90 VSNIFQRRAKYFIFLRFAENG--DLLDFLTQNGA--IPENQSRLWMRQIISGLQYIHTMN 145 + +I +K ++ F + +D +++ GA + + + Q+++G+ + H+ Sbjct: 70 LLDILHAESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNGVNFCHSRR 129 Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205 I HRDLK +N+L+ N+K+ DFG AR+ R+ E +L Y APEVL G + Sbjct: 130 IIHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRNYTHEIV--TLWYRAPEVLLGSRHY 187 Query: 206 PKLADMWSIGVILYTMLNKALPF-NETSVKKLYE 238 D+WS+G I M+ ++ F ++ + ++++ Sbjct: 188 STGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFK 221 >SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 340 Score = 85.8 bits (203), Expect = 8e-18 Identities = 59/219 (26%), Positives = 111/219 (50%), Gaps = 13/219 (5%) Query: 16 IAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRE 75 I+ L + + +GEG+ V H R+ MA K + + L K + RE Sbjct: 58 ISDLDNSSLEVVRHLGEGNGGAVSLVKH-----RNIFMARKTVYVGSDSK--LQKQILRE 110 Query: 76 LDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQII 135 L VL P+IV FQ + + + + + G L L + G IP + + ++ Sbjct: 111 LGVLHHCRSPYIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDILGKIINSMV 170 Query: 136 SGLQYIH-TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYA 194 GL Y++ ++I HRDLK NV+V + +K+ DFG + + + +++T+ G+ +Y Sbjct: 171 KGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGEL----VNSVAQTFVGTSTYM 226 Query: 195 APEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSV 233 +PE ++G Y K +D+WS+G+ + + + LP++ +++ Sbjct: 227 SPERIRGGKYTVK-SDIWSLGISIIELATQELPWSFSNI 264 >SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|Schizosaccharomyces pombe|chr 3|||Manual Length = 624 Score = 85.8 bits (203), Expect = 8e-18 Identities = 43/154 (27%), Positives = 79/154 (51%), Gaps = 3/154 (1%) Query: 19 LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDV 78 +Q F L +G+G Y V+ A H ++A K++ + + K + E D+ Sbjct: 157 IQCSHFDLLVKLGQGGYGSVWLAKK---RNTHELLAMKMMKKSTLQQLNEVKHILNERDI 213 Query: 79 LIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138 L N +V + FQ + K ++ + + GD FLT G + ENQ+R ++ ++++ + Sbjct: 214 LTNTNSEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAI 273 Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFGFA 172 +H + HRDLK EN L+ ++K++DFG + Sbjct: 274 SAVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLS 307 Score = 35.5 bits (78), Expect = 0.012 Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 1/49 (2%) Query: 189 GSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237 GS Y APEV+ G Y + D WS+G I Y L PF+ +++++ + Sbjct: 359 GSPEYMAPEVVYGKKY-DRTVDYWSLGCICYECLVGYPPFSGSTLQETW 406 >SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 85.0 bits (201), Expect = 1e-17 Identities = 54/203 (26%), Positives = 100/203 (49%), Gaps = 5/203 (2%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHI 87 +++G G+ V D ++ + + R+Y K + E + ++H +I Sbjct: 306 RMLGSGAGGSVRIMKRSSDGKIFAVKEFRARRPTETEREYARK-VTAEFCIGSALHHTNI 364 Query: 88 VHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIA 147 + +I + K++ + +A D+ + +G + + +Q++SG+ Y+H+M +A Sbjct: 365 IETLDIVEENKKFYEVMEYAPY-DMFS-IVMSGKMTMPEVYCCFKQLLSGVAYLHSMGLA 422 Query: 148 HRDLKCENVLVTANYNVKITDFGFARNVRQR-DRDVLSET-YCGSLSYAAPEVLKGVPYM 205 HRDLK +N++V +N VKI DFG A + + D++ T GS Y APE L Y Sbjct: 423 HRDLKLDNLVVDSNCFVKIIDFGSAVVFKYPFEADIVEATGVVGSDPYLAPETLVRKLYD 482 Query: 206 PKLADMWSIGVILYTMLNKALPF 228 P+ D+WS +I M + P+ Sbjct: 483 PRAVDIWSSAIIFCCMALRRFPW 505 >SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Schizosaccharomyces pombe|chr 3|||Manual Length = 830 Score = 85.0 bits (201), Expect = 1e-17 Identities = 78/290 (26%), Positives = 131/290 (45%), Gaps = 47/290 (16%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 +++ IG GS+A VYK H ET +++ K + T K + L L E+ +L I Sbjct: 14 YVIRSEIGRGSFAIVYKGKHT--ETNR-VISIKSVLTKKLTKKLLEN-LESEISILKEIR 69 Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQN---GAIP----------------- 123 H H+V + + + + + + GDL F+ + +IP Sbjct: 70 HVHVVELIDCIKAGRFIHLVMEYCSLGDLSYFIRKREKFNSIPSLAWINIDHPPVYKAGL 129 Query: 124 -ENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLV----TANY--------------NV 164 E R + +Q+ S LQ++ + ++ HRD+K +N+L+ TA Y + Sbjct: 130 NETLVRHFTQQLASALQFLRSRSLIHRDVKPQNLLLQPPPTAAYLEEHPQFVGSPKLPML 189 Query: 165 KITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNK 224 K+ DFGFAR ++ ++ET CGS Y APE+L+ Y K AD+WS+G +LY M Sbjct: 190 KLADFGFARYLQTSS---MAETLCGSPLYMAPEILRYEKYDAK-ADLWSVGAVLYEMAVG 245 Query: 225 ALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSR 274 PF + +L + K + + + K + L++ P R Sbjct: 246 KPPFKAPNHVELLRRIQKAKDVIKFPEEAFIHPDIKTLICALLKQNPADR 295 >SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 3|||Manual Length = 781 Score = 84.6 bits (200), Expect = 2e-17 Identities = 59/193 (30%), Positives = 93/193 (48%), Gaps = 14/193 (7%) Query: 67 YLTKFLPRELDVLIRINHPHIVHV------SNIFQRRAK-YFIFLRFAENGDLLDFLT-Q 118 Y+ K L E V R+ HP++V S+IF + + + F GDLL + + Sbjct: 494 YIAK-LASEWLVQCRMEHPNVVKSYDLCIDSHIFPLYSDTWCAVMDFCPRGDLLSLIEDR 552 Query: 119 NGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQR 178 + + + ++QI+ GL YIH+ IAHRD+K EN+L++ ++ITDFG + Sbjct: 553 HDRLGKKDFECMIKQILRGLNYIHSQGIAHRDIKPENILISEYGVLRITDFGACDVLCNP 612 Query: 179 DRDVL-----SETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSV 233 D+ S GS Y APE+L Y ADMWS ++L+ + + PF + S Sbjct: 613 GDDITAVESKSMGIFGSDPYMAPEILTPGSYNAFFADMWSTAIVLHCLYFRTYPFRKASQ 672 Query: 234 KKLYEKQVMRKWR 246 + + WR Sbjct: 673 NDQLYAKYCKAWR 685 >SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schizosaccharomyces pombe|chr 2|||Manual Length = 398 Score = 82.6 bits (195), Expect = 8e-17 Identities = 66/219 (30%), Positives = 114/219 (52%), Gaps = 14/219 (6%) Query: 25 ILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINH 84 ILEK I EGSY VY+ +D++ ++++A K I + L RE++ L I H Sbjct: 76 ILEK-IEEGSYGIVYRG---LDKSTNTLVALKKIKFDPNGIGFPITSL-REIESLSSIRH 130 Query: 85 PHIVHVSNIFQRR--AKYFIFLRFAENG--DLLDFLTQNGAIPENQSRLWMRQIISGLQY 140 +IV + + + ++ + F E+ LLD + ++ +++ + M Q+++ + Sbjct: 131 DNIVELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPED--FLQSEVKTLMLQLLAATAF 188 Query: 141 IHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200 +H HRDLK N+L+ +K+ DFG AR V + + L+ +L Y APE+L Sbjct: 189 MHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSE-PKSSLTRLVV-TLWYRAPELLL 246 Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPFN-ETSVKKLYE 238 G P K DMWSIG I M+ + F+ ++ + +LY+ Sbjct: 247 GAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYK 285 >SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 82.6 bits (195), Expect = 8e-17 Identities = 59/192 (30%), Positives = 94/192 (48%), Gaps = 11/192 (5%) Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIVH 89 IGEG+Y KVYKA + V ++A K I + +D RE+ +L R+ H +IV Sbjct: 283 IGEGTYGKVYKAINTVTG---DLVALKRI-RLEQEKDGFPITTVREVKILQRLRHKNIVR 338 Query: 90 VSNIFQRRAKYFIFLRFAENGDLLDFL--TQNGAIPENQSRLWMRQIISGLQYIHTMNIA 147 + I ++ ++ + ++ DL L +Q P N L +QI L Y+H + Sbjct: 339 LLEIMVEKSSVYMVFEYMDH-DLTGVLLNSQLHFTPGNIKHL-SKQIFEALAYLHHRGVL 396 Query: 148 HRDLKCENVLVTANYNVKITDFGFAR-NVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMP 206 HRD+K N+L+ N ++K DFG AR N + + + +L + PE+L G Sbjct: 397 HRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVI--TLWFRPPELLLGETAYD 454 Query: 207 KLADMWSIGVIL 218 D+WS G I+ Sbjct: 455 TAVDIWSAGCIV 466 >SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces pombe|chr 1|||Manual Length = 471 Score = 82.2 bits (194), Expect = 1e-16 Identities = 58/210 (27%), Positives = 99/210 (47%), Gaps = 10/210 (4%) Query: 19 LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDV 78 L + L + +G GS+ V+KA V I+A K ID D + +E+ + Sbjct: 4 LNANSYTLLRKLGSGSFGVVWKARENVSG---DIIAIKQIDLETGIDDITD--IEQEVFM 58 Query: 79 LIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138 L N +++ F +I + + G + L G + E + +R+++ GL Sbjct: 59 LSNCNSSNVIQYYGCFVDGYTLWILMEHMDGGSVSGLLKM-GRLNEQVISIILREVLYGL 117 Query: 139 QYIHTMNIAHRDLKCENVLVTANY-NVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197 Y+H N HRD+K N+L++++ NVK+ DFG A + + T+ G+ + APE Sbjct: 118 NYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVAAQL--SNAASRRHTFVGTPFWMAPE 175 Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALP 227 V++ Y AD+WS+G+ M N P Sbjct: 176 VIQQTSY-GLAADIWSLGITAIEMANGIPP 204 >SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase Srb10 |Schizosaccharomyces pombe|chr 1|||Manual Length = 352 Score = 81.8 bits (193), Expect = 1e-16 Identities = 71/252 (28%), Positives = 121/252 (48%), Gaps = 14/252 (5%) Query: 23 GFILEKVIGEGSYAKVYKA--THMVDETRHSIMACKVID---TAKAPRDYLTKFLPRELD 77 G+ + I G+Y KVYKA ++ D+ +I K ++ A + +++ RE+ Sbjct: 4 GYKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMM 63 Query: 78 VLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFL-----TQNGAIPENQSRLWMR 132 + I H +IV + + + + +AE+ DLL + ++ IP + + + Sbjct: 64 LCREIQHENIVSLVQVLLKDGTISMVFEYAEH-DLLQIIHFHSRSRTRQIPPSILKSILW 122 Query: 133 QIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVL-SETYCGSL 191 QII+G+ Y+H I HRDLK N+++TA VKI D G R +R S+ ++ Sbjct: 123 QIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFYSSDRVVVTI 182 Query: 192 SYAAPEVLKGV-PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTT 250 Y APE+L G Y P + D+W+IG I ML + F +K +K V + Sbjct: 183 WYRAPELLLGAHDYTPAI-DVWAIGCIYGEMLALSPLFKGDEIKMEDKKVVPFQSTQMLR 241 Query: 251 VVNQLSTECKEQ 262 ++ L T +E+ Sbjct: 242 IMELLGTPTEER 253 >SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase kinase Win1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1436 Score = 81.0 bits (191), Expect = 2e-16 Identities = 52/168 (30%), Positives = 91/168 (54%), Gaps = 10/168 (5%) Query: 8 DLSTTQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDY 67 +L++++S+I + ++G + IG GS+ VY+A ++ +MA K + K PR Sbjct: 1108 ELASSKSNITIRWQQGGL----IGSGSFGTVYRAVNL---DTGDLMAVKEVALHK-PRIS 1159 Query: 68 --LTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPEN 125 + K + E+ VL +HP++V I R K IF+ + L +FL E Sbjct: 1160 RPMIKRIKGEMLVLELFDHPNVVSYYGIEVHREKVNIFMELCQGSSLFEFLRYGRIEDEL 1219 Query: 126 QSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFAR 173 ++++ Q++ GL YIH+ ++H+D+K EN+L N +K TDFG A+ Sbjct: 1220 VIQVYVLQLLEGLAYIHSCGVSHQDVKPENILFDHNGIMKFTDFGSAK 1267 >SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosaccharomyces pombe|chr 2|||Manual Length = 652 Score = 80.6 bits (190), Expect = 3e-16 Identities = 71/275 (25%), Positives = 129/275 (46%), Gaps = 26/275 (9%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHI 87 +++G GSY VY+ + + T+ ++ A K+++ D ++ + +E+ VL + Sbjct: 14 ELVGRGSYGAVYRG--ICNLTKETV-AIKILNL-DTDEDEVSD-IQKEVAVLSELKQSD- 67 Query: 88 VHVSNIFQRRAKY------FIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141 V NI + Y +I + + G + L + G I E L +R+ + L++I Sbjct: 68 --VENIIKYHGSYLVGTNLWIIMDYCHGGSVRT-LMEAGPISEPCISLILRETLQALKFI 124 Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFGFAR--NVRQRDRDVLSETYCGSLSYAAPEVL 199 H I HRD+K N+LV+ + NVK+ DFG A N+ +R R T+ G+ + APEV+ Sbjct: 125 HHAGIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRKR----ITFIGTPYWMAPEVI 180 Query: 200 KGVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258 + +AD+WS+G+ Y + + P E + +Y R S Sbjct: 181 RDGQEYNVMADIWSLGITAYEIATGSPPHAKEDPFRAVYLIAHTAPPRLN----GNFSAL 236 Query: 259 CKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLA 293 KE + ++ P+ R +S + +I SR++ Sbjct: 237 LKEFIASCLQDVPQRRLDSSELLKSKFIKQYSRMS 271 >SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomyces pombe|chr 2|||Manual Length = 581 Score = 79.0 bits (186), Expect = 1e-15 Identities = 62/214 (28%), Positives = 107/214 (50%), Gaps = 12/214 (5%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINH-PH 86 K I E ++ VY + + T ++ K++ A + L +E+ +L R+ P Sbjct: 293 KPIHESDFSFVYHVSSINPPTE-TVYVVKMLKKNAAKFTGKERHL-QEVSILQRLQACPF 350 Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPE-NQSRLW--MRQIISGLQYIHT 143 +V++ N++ F+ L + ENGDL FL++ G + + R+W + Q+ L +IH Sbjct: 351 VVNLVNVWSYNDNIFLQLDYCENGDLSLFLSELGLLQVMDPFRVWKMLFQLTQALNFIHL 410 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203 + H D+K NVL+T + N+K+ DFG A ++ L G Y APE+L Sbjct: 411 LEFVHLDVKPSNVLITRDGNLKLGDFGLATSLPVSSMVDLE----GDRVYIAPEILASHN 466 Query: 204 YMPKLADMWSIGV-ILYTMLNKALPFNETSVKKL 236 Y K AD++S+G+ ++ N LP N ++L Sbjct: 467 Y-GKPADVYSLGLSMIEAATNVVLPENGVEWQRL 499 >SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizosaccharomyces pombe|chr 2|||Manual Length = 413 Score = 79.0 bits (186), Expect = 1e-15 Identities = 51/177 (28%), Positives = 91/177 (51%), Gaps = 20/177 (11%) Query: 70 KFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGA--IPENQS 127 K +E+ L ++HP +V + N + A+ + + GDL + ++ + E Sbjct: 150 KVFRQEIWALKTLSHPCVVQLLNYYVSSAELILVENYCMGGDLYHYTKKHHSDFSLEFVG 209 Query: 128 RLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNV---------------KITDFGFA 172 R++ +++ + Y+H+ + HRDLK EN+L+T YNV +I+DF + Sbjct: 210 RIFS-ELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTIDNWKNYPNALIQISDFELS 268 Query: 173 RNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFN 229 V ++ L ++ CGS YA PEV G+ + AD WS+G++L+ +L LPF+ Sbjct: 269 IFVDSKNH--LVQSSCGSQEYAPPEVYMGIAHDGFRADAWSLGIVLFALLEGRLPFD 323 >SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyces pombe|chr 1|||Manual Length = 349 Score = 77.0 bits (181), Expect = 4e-15 Identities = 56/193 (29%), Positives = 91/193 (47%), Gaps = 10/193 (5%) Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIVH 89 IG G++ V A + T ++ K++ P L K REL +L + H +I+ Sbjct: 26 IGMGAFGLVCSAKDQL--TGMNVAVKKIMKPFSTP--VLAKRTYRELKLLKHLRHENIIS 81 Query: 90 VSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHR 149 +S+IF + F+ DL LT + + ++ QI+ GL+++H+ + HR Sbjct: 82 LSDIFISPFEDIYFVTELLGTDLHRLLTSR-PLETQFIQYFLYQILRGLKFVHSAGVIHR 140 Query: 150 DLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLA 209 DLK N+L+ N ++KI DFG A R +D Y + Y APE++ Sbjct: 141 DLKPSNILINENCDLKICDFGLA-----RIQDPQMTGYVSTRYYRAPEIMLTWQKYNVEV 195 Query: 210 DMWSIGVILYTML 222 D+WS G I M+ Sbjct: 196 DIWSAGCIFAEMI 208 >SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 372 Score = 76.6 bits (180), Expect = 5e-15 Identities = 62/232 (26%), Positives = 108/232 (46%), Gaps = 17/232 (7%) Query: 2 GGGDKIDLSTTQS----DIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKV 57 G +K ++T++S D+ + + + +IG+G+Y V A H + +A K Sbjct: 13 GNSNKESVATSRSPHTHDLNFELPEEYEMINLIGQGAYGVVCAALHKPSGLK---VAVKK 69 Query: 58 IDTAKAPRDYLTKFLPRELDVLIRINHPHIVHVSNI-----FQRRAKYFIFLRFAENGDL 112 I P L RE+ +L H +I+ + +I +Q +I E DL Sbjct: 70 IHPFNHPVFCLRTL--REIKLLRHFRHENIISILDILPPPSYQELEDVYIVQELMET-DL 126 Query: 113 LDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFA 172 + ++ + ++ + + QI+ L+ +H+ + HRDLK N+L+ AN ++K+ DFG A Sbjct: 127 YRVI-RSQPLSDDHCQYFTYQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLA 185 Query: 173 RN-VRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLN 223 R+ Q Y + Y APE++ K D+WS G IL ML+ Sbjct: 186 RSTTAQGGNPGFMTEYVATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLS 237 >SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating kinase Crk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 335 Score = 76.6 bits (180), Expect = 5e-15 Identities = 55/210 (26%), Positives = 100/210 (47%), Gaps = 11/210 (5%) Query: 15 DIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR 74 DI + ++ E+ +GEG+YA V+ R +I KV +D + R Sbjct: 2 DIEKSDKWTYVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQF----KDGIDISALR 57 Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRL--WMR 132 E+ L H +++ + ++F ++ I L F ++ L+ L ++ I + + WM Sbjct: 58 EIKFLRESRHDNVIELVDVFSTKSNLNIILEFLDSD--LEMLIKDKFIVFQPAHIKSWMV 115 Query: 133 QIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLS 192 ++ GL +IH+ I HRDLK N+L++++ +K+ DFG +R+ +S + Sbjct: 116 MLLRGLHHIHSRFILHRDLKPNNLLISSDGVLKLADFGLSRDFGTPSH--MSHQVI-TRW 172 Query: 193 YAAPEVLKGVPYMPKLADMWSIGVILYTML 222 Y PE+ G DMWS+G I ++ Sbjct: 173 YRPPELFMGCRSYGTGVDMWSVGCIFAELM 202 >SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizosaccharomyces pombe|chr 1|||Manual Length = 566 Score = 76.2 bits (179), Expect = 7e-15 Identities = 60/274 (21%), Positives = 118/274 (43%), Gaps = 32/274 (11%) Query: 29 VIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIV 88 ++G+G +VY ++ A KV+ + + +K E +L NHP IV Sbjct: 200 LLGKGDVGRVYLVR---EKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILATSNHPFIV 256 Query: 89 HVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGA--IPENQSRLWMRQIISGLQYIHTMNI 146 + + FQ ++ + + G+ L + + EN+++ ++ ++ + L+Y+H M Sbjct: 257 TLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLMGF 316 Query: 147 AHRDLKCENVLVTANYNVKITDFGF--------------ARNVRQRDR-----------D 181 +RDLK EN+L+ + ++ ++DF ARN D Sbjct: 317 IYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYALDTKSCIAD 376 Query: 182 VLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQV 241 + ++ G+ Y APEV+KG + D W++G++ Y ML PF + + + Sbjct: 377 FRTNSFVGTEEYIAPEVIKGCGH-TSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNIL 435 Query: 242 MRKWRF-RTTVVNQLSTECKEQVTQLMEPEPKSR 274 + F +S+ CK + +L+ + R Sbjct: 436 HKDVIFPEYADAPSISSLCKNLIRKLLVKDENDR 469 >SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosaccharomyces pombe|chr 1|||Manual Length = 469 Score = 74.9 bits (176), Expect = 2e-14 Identities = 42/162 (25%), Positives = 82/162 (50%), Gaps = 3/162 (1%) Query: 19 LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDV 78 L + F KVIG+G++ +V + +D + M ++ T RD L + E D+ Sbjct: 88 LSLEDFSTIKVIGKGAFGEV-RLVQKLDTGKIYAMK-SLLKTEMFKRDQLAH-VKAERDL 144 Query: 79 LIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138 L+ + P +V + FQ ++ + F GDL+ L E+ +R +M + + + Sbjct: 145 LVESDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAI 204 Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDR 180 +H M HRD+K +N+L+ + ++K++DFG + ++D+ Sbjct: 205 ADVHRMGYIHRDIKPDNILIDRDGHIKLSDFGLSTGFYKQDQ 246 Score = 38.7 bits (86), Expect = 0.001 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 5/93 (5%) Query: 177 QRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKL 236 +++R V++ + G+ Y APE+ Y D WS+G I++ L PF + + Sbjct: 282 KKNRRVMAYSTVGTPDYIAPEIFLQQGYGQD-CDWWSLGAIMFECLIGWPPFCSENSHET 340 Query: 237 YEKQVMRKWRFRTTVVN--QLSTECKEQVTQLM 267 Y K + WR T N LS E ++ + +LM Sbjct: 341 YRKII--NWRETLTFPNDIHLSIEARDLMDRLM 371 >SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity protein kinase Mph1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 678 Score = 74.9 bits (176), Expect = 2e-14 Identities = 60/231 (25%), Positives = 114/231 (49%), Gaps = 21/231 (9%) Query: 13 QSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFL 72 Q D+ + FI V+G+G + VY+ D +R + A K ++ A + + + Sbjct: 305 QQDVVTVANLQFIKLGVVGKGGSSMVYRI-FSPDNSR--LYALKEVNFINADQTTIQGY- 360 Query: 73 PRELDVLIRIN-HPHIV--HVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQS-- 127 E+ +L +++ + I+ + + + + + + E DL + L +N P N + Sbjct: 361 KNEIALLRKLSGNDRIIKLYAAEVNDTLGQLNMVMECGET-DLANLLMKNMKKPINLNFI 419 Query: 128 RLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETY 187 R++ Q++ +Q +H NI H DLK N L+ N+K+ DFG A+ + ++ +++ Sbjct: 420 RMYWEQMLEAVQVVHDQNIVHSDLKPANFLLVEG-NLKLIDFGIAKAIGNDTTNIHRDSH 478 Query: 188 CGSLSYAAPEVL--------KGVPY--MPKLADMWSIGVILYTMLNKALPF 228 G+++Y APE L GV + + +D+WS+G ILY M+ PF Sbjct: 479 IGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQMVYGRAPF 529 >SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schizosaccharomyces pombe|chr 2|||Manual Length = 526 Score = 74.5 bits (175), Expect = 2e-14 Identities = 54/275 (19%), Positives = 122/275 (44%), Gaps = 32/275 (11%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHI 87 +++G+G KVY ++ H + A K+++ + + + + E ++L + HP I Sbjct: 159 RLLGQGDVGKVYLVRQ---KSNHRLFAMKILNKREMIKRHKVNRVLAEQEILTKSKHPFI 215 Query: 88 VHVSNIFQRRAKYFIFLRFAENGDLLDFLTQ--NGAIPENQSRLWMRQIISGLQYIHTMN 145 V + + FQ R ++ + + G+ L +PE + + ++ + L+Y+H M Sbjct: 216 VTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAALEYLHLMG 275 Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVR---------------QRDRDVL------- 183 +RDLK EN+L+ + ++ ++DF ++ + +++ L Sbjct: 276 FIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQEKPALDTNSYFS 335 Query: 184 ---SETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQ 240 + ++ G+ Y APEV++ + + D W++G+ +Y +L PF + + Sbjct: 336 NFRTNSFVGTEEYIAPEVIRSCGHTVAV-DWWTLGIFIYEILYGTTPFKGKNRHATFSNI 394 Query: 241 VMRKWRF-RTTVVNQLSTECKEQVTQLMEPEPKSR 274 + F +S+ CK + +L+ + R Sbjct: 395 LYSDVSFPEYHGAPNVSSTCKSLIRRLLVKDESKR 429 >SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosaccharomyces pombe|chr 1|||Manual Length = 650 Score = 74.1 bits (174), Expect = 3e-14 Identities = 61/211 (28%), Positives = 102/211 (48%), Gaps = 17/211 (8%) Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN-HPHIV 88 +G+G++ VY AT ++A K + A T+ RE+ L+R++ + +IV Sbjct: 42 VGDGTFGSVYLATTKTPSKE--VVAIKSMKKKLAKVSDATRL--REVHSLLRLSENENIV 97 Query: 89 HVSNIF--QRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146 ++ +++ Q R + + N L +N + Q + MRQI GL +IHT Sbjct: 98 NIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHTNGF 157 Query: 147 AHRDLKCENVLVTAN-----YNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKG 201 HRD+K EN+L+++N +NVKI DFG AR + R Y + Y APE+L Sbjct: 158 FHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPP---YTEYVSTRWYRAPELLLR 214 Query: 202 VPYMPKLADMWSIGVILYTM--LNKALPFNE 230 Y D+++ G + + + L P N+ Sbjct: 215 DSYYSFPVDIYAAGCMAFEIATLQPIFPGND 245 >SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Ppk34|Schizosaccharomyces pombe|chr 3|||Manual Length = 354 Score = 73.3 bits (172), Expect = 5e-14 Identities = 49/171 (28%), Positives = 85/171 (49%), Gaps = 13/171 (7%) Query: 71 FLPRELDVLIRINHPHIVHVSNIFQRRAK--YFIFLRFAENGDL--LDFLTQNGAIPENQ 126 ++ +ELDVL ++H ++V + + K + L + G L +D +P Sbjct: 117 YIRKELDVLKVLDHENVVKLYQVINSDYKDSLCMVLNYCPGGKLASVDHGISFDPMPLET 176 Query: 127 SRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSET 186 R RQ++ + YIH + HRD+K +N+L N N+ + DFG A + +D + Sbjct: 177 CRKSFRQLVLAVNYIHGKGVIHRDIKPDNILFKENNNLCVIDFGLAEFL---PKDGFVKP 233 Query: 187 YCGSLSYAAPEV----LKGVPYMPKLADMWSIGVILYTMLNKALPFNETSV 233 G+ ++ APE+ LK + P D+WS+GV LY + PFN +++ Sbjct: 234 ASGTPAFMAPELFDNELKKIKGKP--LDIWSMGVTLYVIAFAEFPFNGSTI 282 >SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schizosaccharomyces pombe|chr 1|||Manual Length = 504 Score = 72.9 bits (171), Expect = 6e-14 Identities = 41/129 (31%), Positives = 69/129 (53%), Gaps = 5/129 (3%) Query: 164 VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLN 223 + I DFGF++ V + T CG++ YAAPE++ Y K DMW++G +L+TML Sbjct: 234 ILIADFGFSKVVWNSK----TATPCGTVGYAAPEIVNDELYS-KNVDMWAMGCVLHTMLC 288 Query: 224 KALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNG 283 PF + ++K L K V ++ F + + +S K+ +T L+ +P+ R F Sbjct: 289 GFPPFFDENIKDLASKVVNGEFEFLSPWWDDISDSAKDLITHLLTVDPRERYDIHQFFQH 348 Query: 284 TWIGMDSRL 292 WI +S++ Sbjct: 349 PWIKGESKM 357 Score = 60.5 bits (140), Expect = 4e-10 Identities = 37/138 (26%), Positives = 76/138 (55%), Gaps = 6/138 (4%) Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80 EK ++E +G+G++++VYKA + +D H +A KVI + + +E++++ Sbjct: 63 EKYQLIEN-LGDGAFSQVYKA-YSIDRKEH--VAVKVIRKYEMNKKQRQGVF-KEVNIMR 117 Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140 R+ H ++V++ + + Y + + AE G+L + EN +R + Q+ +++ Sbjct: 118 RVKHKNVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLARHIIIQVAEAVKH 177 Query: 141 IHTM-NIAHRDLKCENVL 157 +H + I HRD+K EN+L Sbjct: 178 LHDVCGIVHRDIKPENLL 195 >SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomyces pombe|chr 1|||Manual Length = 607 Score = 72.1 bits (169), Expect = 1e-13 Identities = 37/146 (25%), Positives = 76/146 (52%), Gaps = 3/146 (2%) Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIVH 89 +G+G Y V+ A +T+ I+A K+++ + + + + E D+L N +V Sbjct: 214 VGQGGYGSVWLARKR--DTKE-IVALKIMNKSVLHKMDEIRHVLTERDILTTANSEWLVR 270 Query: 90 VSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHR 149 + FQ + ++ + F GD L+ +G + ++ ++ + ++ + +H + HR Sbjct: 271 LLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRDHHAKFYATEMFLAIDALHQLGYIHR 330 Query: 150 DLKCENVLVTANYNVKITDFGFARNV 175 DLK EN LV A+ ++K+TDFG + + Sbjct: 331 DLKPENFLVGASGHIKLTDFGLSSGI 356 Score = 44.4 bits (100), Expect = 3e-05 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 182 VLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQV 241 V + + GS Y APEVL+G Y + D WS+G I+Y L+ PF+ ++V + + Sbjct: 398 VYAHSVVGSPDYMAPEVLRGENYNHSV-DYWSLGCIMYECLSGFPPFSGSNVNETWSN-- 454 Query: 242 MRKWR 246 ++ WR Sbjct: 455 LKNWR 459 >SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosaccharomyces pombe|chr 1|||Manual Length = 722 Score = 72.1 bits (169), Expect = 1e-13 Identities = 58/241 (24%), Positives = 115/241 (47%), Gaps = 33/241 (13%) Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80 EK ILE IG GS+ ++YK + D +++A K I R +++ E+++L Sbjct: 2 EKYKILE-CIGHGSFGRIYKVQRLKDG---ALLAQKEIHFGNITRQE-KQYIADEVNILR 56 Query: 81 RINHPHIV-HVSNIFQRRAKYF-IFLRFAENGDLLDFLT----QNGAIPENQSRLWMRQI 134 + HP+IV + R A+ +++ + +GDL + + + E + + Q+ Sbjct: 57 NLKHPNIVQYCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQL 116 Query: 135 ISGLQYIH-------------------TMNIAHRDLKCENVLVTANYNVKITDFGFARNV 175 + L H ++ HRD+K N+ + N +VK+ DFG ++ + Sbjct: 117 LLALYRCHYGENAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLL 176 Query: 176 RQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKK 235 + V +++Y G+ Y +PE+++ PY K +D+W++G +++ + PF S + Sbjct: 177 --DNTRVFTQSYVGTPYYMSPEIIRSSPYSAK-SDVWALGCVIFEICMLTHPFEGRSYLE 233 Query: 236 L 236 L Sbjct: 234 L 234 >SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizosaccharomyces pombe|chr 2|||Manual Length = 591 Score = 71.3 bits (167), Expect = 2e-13 Identities = 58/218 (26%), Positives = 108/218 (49%), Gaps = 28/218 (12%) Query: 25 ILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINH 84 ++EK +GEG++ +VYK+ D +++ +++ + +T RE+ +L I H Sbjct: 38 LMEK-LGEGTFGEVYKSQRRKDGKVYALK--RILMHTEKEGFPITAI--REIKILKSIKH 92 Query: 85 PHIVHVSNI--------FQRRAKYFIFLRFAENGDLLDFLTQNGAIP--ENQSRLWMRQI 134 +I+ +S++ +RR ++ + ++ L L +N ++ E Q + +M+Q+ Sbjct: 93 ENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHD--LSGLLENPSVKFTEPQIKCYMKQL 150 Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLS--------ET 186 +G +Y+H I HRDLK N+L+ + +KI DFG AR + + + Sbjct: 151 FAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRRE 210 Query: 187 YCGSLS---YAAPEVLKGVPYMPKLADMWSIGVILYTM 221 Y G + Y +PE+L G DMWS+G I+ M Sbjct: 211 YTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEM 248 >SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosaccharomyces pombe|chr 2|||Manual Length = 559 Score = 70.9 bits (166), Expect = 3e-13 Identities = 56/213 (26%), Positives = 102/213 (47%), Gaps = 14/213 (6%) Query: 18 VLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELD 77 V+ E +++++ +G+GS+ VY A + +A K + + P+ RE Sbjct: 15 VIFEDRYLVKQKLGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESL 74 Query: 78 VLIRIN-HPHIVHVSNIFQRRAK-YFIFLRFAENGDLLDFLTQNGAIPENQSRL-WMRQI 134 L +I+ HP ++ + F + F+ + F + F + G + ++ + QI Sbjct: 75 ALRKISKHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQI 134 Query: 135 ISGLQYIHTMNIAHRDLKCENVLV--------TANYNVKITDFGFARNVRQRDRDVLSET 186 ISG+++IH HRD+K EN+LV ++ Y++K+ DFG AR D L+E Sbjct: 135 ISGIEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLAR--PSVSSDPLTE- 191 Query: 187 YCGSLSYAAPEVLKGVPYMPKLADMWSIGVILY 219 Y + Y APE+L D+++ G I++ Sbjct: 192 YVSTRWYRAPELLLRSGSYNHSVDLYAFGCIVF 224 >SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gcn2 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1576 Score = 69.3 bits (162), Expect = 8e-13 Identities = 49/138 (35%), Positives = 71/138 (51%), Gaps = 17/138 (12%) Query: 98 AKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVL 157 A +I + + E L D + IP ++ RQI+ L YIH+ + HRDLK N+ Sbjct: 722 ATLYIQMEYCEKLSLQDIIRDK--IPVDEMWRLFRQILEALAYIHSRGMMHRDLKPGNIF 779 Query: 158 VTANYNVKITDFGFA--------RNVRQRDRDVLSE---TYCGSLSYAAPEVL---KGVP 203 + N NVK+ DFG A N + ++R E T G+ Y APE+L GV Sbjct: 780 LDENRNVKLGDFGLATENENYQDNNDKWKNRQSADEDLTTGVGTALYVAPELLSRRNGVR 839 Query: 204 YMPKLADMWSIGVILYTM 221 Y K+ DM+S+G+IL+ M Sbjct: 840 YDAKV-DMYSLGIILFEM 856 Score = 42.3 bits (95), Expect = 1e-04 Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 10/125 (8%) Query: 128 RLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLS 184 R + I+ GL +H + I+H+ L +NV++ + + K+ DFGF R +R + Sbjct: 352 RAFSNNILEGLAELHRLGISHKSLHLDNVVLFHSGHRTFAKLMDFGFTRTLRDMNASHPF 411 Query: 185 ETYCGSLSYAAPEVL-------KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237 S++ PE L + D+W G+++ ML A N+ S KL Sbjct: 412 NINSQSITNILPEGLYPPEVSESSFAAASRKTDIWCFGLLVLQMLCGAHVLNKFSSLKLI 471 Query: 238 EKQVM 242 V+ Sbjct: 472 MTHVI 476 >SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 363 Score = 68.9 bits (161), Expect = 1e-12 Identities = 62/212 (29%), Positives = 94/212 (44%), Gaps = 16/212 (7%) Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82 G + +GEG V K + T+ I A K + AP L K L REL + Sbjct: 78 GILYMNSLGEGVSGSVRKCR--IRGTQ-MIFAMKTV--LAAPNTALQKQLLRELKINRSC 132 Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENG-DLLDFL-----TQNGAIPENQSRLWMRQIIS 136 P+IV A+ + + G LD + +Q G E ++S Sbjct: 133 TSPYIVKYYGACYNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTGERPLGKIAFGVLS 192 Query: 137 GLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAP 196 GL Y+H I HRD+K N+L+T+ VK+ DFG + + + L+ T+ G+ Y AP Sbjct: 193 GLSYLHDRKIIHRDIKPSNILLTSKGQVKLCDFGVSGEL----VNSLAGTFTGTSYYMAP 248 Query: 197 EVLKGVPYMPKLADMWSIGVILYTMLNKALPF 228 E + G Y +D+WS+G+ L + PF Sbjct: 249 ERISGGSYTIS-SDIWSLGLTLMEVALNRFPF 279 >SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosaccharomyces pombe|chr 3|||Manual Length = 477 Score = 68.5 bits (160), Expect = 1e-12 Identities = 55/210 (26%), Positives = 94/210 (44%), Gaps = 13/210 (6%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKF-LPRELDVLIR 81 +I++ +G+G ++ V A +D R+ A K+I + ++ L + + L R Sbjct: 159 YIVQSNLGKGMFSTVVSA---LDRNRNQTFAIKIIRNNEVMYKEGLKEVSILERLQAADR 215 Query: 82 INHPHIVHVSNIFQRRAKY-FIFLRFAEN-GDLLDFLTQNGAIPENQSRLWMRQIISGLQ 139 HI+H F + +F + N D+L +N + RL+ Q+ L Sbjct: 216 EGKQHIIHYERHFMHKNHLCMVFEMLSLNLRDILKKFGRNVGLSIKAVRLYAYQMFMALD 275 Query: 140 YIHTMNIAHRDLKCENVLVTANYNV-KITDFGFARNVRQRDRDVLSETYCGSLSYAAPEV 198 + N+ H D+K +N+LV N+ KI D G A + + + Y S Y APE+ Sbjct: 276 LLKQCNVIHSDIKPDNMLVNEKRNILKICDLGSASDASENE----ITPYLVSRFYRAPEI 331 Query: 199 LKGVPYMPKLADMWSIGVILYTMLNKALPF 228 + G PY + D WS+G LY + + F Sbjct: 332 ILGFPYSCPI-DTWSVGCSLYELYTGQILF 360 >SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizosaccharomyces pombe|chr 2|||Manual Length = 381 Score = 67.3 bits (157), Expect = 3e-12 Identities = 48/180 (26%), Positives = 88/180 (48%), Gaps = 14/180 (7%) Query: 70 KFLPRELDVLIRINHPHIV------HVSNIFQRRAKYFIFLRFAEN---GDLLDFLTQNG 120 ++ REL ++ I+HP+I+ H N + + L + D+ + + Sbjct: 61 RYKNRELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRK 120 Query: 121 AIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNV-KITDFGFARNVRQRD 179 +IP +L+ Q+ L Y+H+ + HRD+K +N+LV + K+ DFG A+ + + Sbjct: 121 SIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPSE 180 Query: 180 RDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIG-VILYTMLNKALPFNETSVKKLYE 238 +V +Y S Y APE++ G + D+WS VI + + L ++SV++L E Sbjct: 181 PNV---SYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVE 237 >SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 580 Score = 66.1 bits (154), Expect = 7e-12 Identities = 36/123 (29%), Positives = 66/123 (53%), Gaps = 5/123 (4%) Query: 164 VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLN 223 +++ DFG ++ V D ++T CG++ Y APE+++ Y K DMW++G +LYT+L Sbjct: 304 IRLADFGLSKVVW----DSHTQTPCGTMGYTAPEIVRDERYS-KGVDMWALGCVLYTILC 358 Query: 224 KALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNG 283 PF + S+ L +K ++ F + + +S K+ ++ L+ +P+SR Sbjct: 359 GFPPFYDESISLLTKKVSRGEYSFLSPWWDDISKSAKDLISHLLTVDPESRYDIHQFLAH 418 Query: 284 TWI 286 WI Sbjct: 419 PWI 421 Score = 64.5 bits (150), Expect = 2e-11 Identities = 42/147 (28%), Positives = 79/147 (53%), Gaps = 14/147 (9%) Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKA---PRDYLTKF------ 71 E+ +L+K+ G+G+++ VYKA H + T + A KV+ A+ PRD + Sbjct: 122 EQYTLLQKM-GDGAFSNVYKAIH--NRTGEKV-AIKVVQRAQPNTDPRDPRKRQGVESHN 177 Query: 72 LPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWM 131 + +E+ ++ R+ HP+I+ + Q Y++ L A+ G+L + + E+ SR + Sbjct: 178 ILKEVQIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSRHVI 237 Query: 132 RQIISGLQYIH-TMNIAHRDLKCENVL 157 Q+ ++Y+H + HRD+K EN+L Sbjct: 238 TQVAHAIRYLHEDCGVVHRDIKPENLL 264 >SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1316 Score = 64.5 bits (150), Expect = 2e-11 Identities = 31/146 (21%), Positives = 72/146 (49%), Gaps = 2/146 (1%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHI 87 K I +G++ VY + ++I + +D ++ + ++ + + Sbjct: 568 KPISKGTFGTVYLSRKNTTGEIYAIKVLRKVDMIS--KNQVANVKAERAVLMAQEESAFV 625 Query: 88 VHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIA 147 + FQ R ++ + F GD L IPE+ +++++ ++ GL+++H + I Sbjct: 626 AKLYYAFQSRDYLYLVMEFMNGGDCASLLKSLYTIPESWAKIYIAEVALGLEHLHRLGII 685 Query: 148 HRDLKCENVLVTANYNVKITDFGFAR 173 HRD+K +N+L++ ++K+ DFG ++ Sbjct: 686 HRDIKPDNILMSITGHLKLADFGLSQ 711 Score = 41.9 bits (94), Expect = 1e-04 Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 1/88 (1%) Query: 187 YCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWR 246 + G+ Y APE L+G + D W++G +L+ L PF+ + +K++E + Sbjct: 831 FVGTPDYLAPETLRGST-QDDMVDWWALGCVLFEFLFGYPPFHAETPEKVFENILANNIA 889 Query: 247 FRTTVVNQLSTECKEQVTQLMEPEPKSR 274 + + S E + + ++P P+ R Sbjct: 890 WPDLEMYPCSEEALDLINGFLQPNPERR 917 >SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 387 Score = 62.9 bits (146), Expect = 7e-11 Identities = 62/231 (26%), Positives = 108/231 (46%), Gaps = 24/231 (10%) Query: 19 LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDV 78 +++ + KV+G GS+ V + H+++ S A K + K +F REL + Sbjct: 27 VKQLSYTSSKVVGSGSFGVVMQV-HLIESD--SKAAIKRVLQDK-------RFKNRELQI 76 Query: 79 LIRINHPHIVHVSNIFQRRAK-----YF-IFLRFAENGDLLD---FLTQNGAIPENQSRL 129 + + HP+IV + + Y + L F + Q ++P + +L Sbjct: 77 MRIMKHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKL 136 Query: 130 WMRQIISGLQYIHTMNIAHRDLKCENVLV-TANYNVKITDFGFARNVRQRDRDVLSETYC 188 ++ Q++ L YIH I HRD+K +N+L+ N +K+ DFG A+ + + +V +Y Sbjct: 137 YIYQLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVAGEPNV---SYI 193 Query: 189 GSLSYAAPEVLKGVPYMPKLADMWSIG-VILYTMLNKALPFNETSVKKLYE 238 S Y APE++ G D+WS G V+ ML L E+ + +L E Sbjct: 194 CSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVE 244 >SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizosaccharomyces pombe|chr 2|||Manual Length = 872 Score = 61.3 bits (142), Expect = 2e-10 Identities = 61/235 (25%), Positives = 106/235 (45%), Gaps = 28/235 (11%) Query: 18 VLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELD 77 V+ + +EK I EG ++ VY I A V+ +P + +F+ E++ Sbjct: 19 VIGKYNVTIEKYIAEGGFSHVYLVQTNSKTDGSPITA--VLKRMYSPDENALRFVKTEIE 76 Query: 78 VLIRI-NHPHIVHV--SNIFQRRA-------KYFIFLRFAENGDLLDFLTQN--GAIPEN 125 + + ++PH+V S IF + + + + G L+DF+ Q + E+ Sbjct: 77 TMELLKSNPHVVSYIDSCIFPLEKAGVNTGFEILLLMEYCAGGGLIDFMNQRLQTRLSEH 136 Query: 126 QSRLWMRQIISGLQYIHTMN--IAHRDLKCENVLVTANYNVKITDFGF-------ARNVR 176 + + I+ G+ +H + + HRDLK ENVL++ N K+ DFG A N Sbjct: 137 EVLKIISDIVQGVASLHYLRPPLIHRDLKVENVLLSFN-TFKLCDFGSVTEPMHAAENSS 195 Query: 177 QRDRDVLSETYCGSLSYAAPEVLK---GVPYMPKLADMWSIGVILYTMLNKALPF 228 + S + Y APE++ G+ K +DMW++GV+LY + PF Sbjct: 196 EIQALEKSINTFTTYQYRAPEMINLYSGLGIDEK-SDMWALGVLLYKLCYYTTPF 249 >SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1032 Score = 58.4 bits (135), Expect = 1e-09 Identities = 41/158 (25%), Positives = 75/158 (47%), Gaps = 8/158 (5%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKF---LPRELDVLI 80 FIL K I G+Y +VY A + A K+I K+ D L K L + ++ I Sbjct: 528 FILLKEINRGAYGRVYLAKK---RSSGKYFALKMIP--KSSLDSLKKIKGLLLEKRNMHI 582 Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140 + P+ V + F + + + GD + + G +PE + ++++ ++ Sbjct: 583 QRYGPNTVKLYYAFDSGDYLCLVMDYFNGGDCETLIQKLGPLPEQWVCQYAAELLNAIEL 642 Query: 141 IHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQR 178 +H I H D+K N+LV ++++TDFG + NV ++ Sbjct: 643 LHQDGIIHHDIKPANMLVDETGHIRLTDFGLSENVEEK 680 Score = 54.4 bits (125), Expect = 2e-08 Identities = 26/99 (26%), Positives = 52/99 (52%), Gaps = 2/99 (2%) Query: 176 RQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKK 235 ++ +R + + G+ +Y APE+L GV ++ D+W++G +++ ML PF +VK Sbjct: 766 KKENRTFIKKDISGTPNYMAPEILMGVD--TQMGDIWAMGCVIFEMLTGTRPFEANTVKA 823 Query: 236 LYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSR 274 ++ + + V S E + +T+LM+P+ R Sbjct: 824 IWARIERNDIGWTKRVKESCSKEAVDLITKLMDPDCNKR 862 >SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1338 Score = 56.4 bits (130), Expect = 6e-09 Identities = 34/147 (23%), Positives = 68/147 (46%), Gaps = 4/147 (2%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKA-PRDYLTKFLPRELDVLIRINHPH 86 K I +G++ VY A T A K++ + ++ + ++ + P Sbjct: 593 KPISKGAFGSVYLAQK---RTTGDYFAIKILKKSNMIAKNQVINVRAERAILMSQGESPF 649 Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146 + + FQ + ++ + + GD L G + + R ++ + + L +H I Sbjct: 650 VAKLYYTFQSKDYLYLVMEYLNGGDCGSLLKTMGVLDLDWIRTYIAETVLCLGDLHDRGI 709 Query: 147 AHRDLKCENVLVTANYNVKITDFGFAR 173 HRD+K EN+L++ N ++K+TDFG +R Sbjct: 710 IHRDIKPENLLISQNGHLKLTDFGLSR 736 Score = 46.4 bits (105), Expect = 6e-06 Identities = 26/97 (26%), Positives = 51/97 (52%), Gaps = 1/97 (1%) Query: 184 SETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR 243 S+ + G+ Y APEV+ G P + K +D WS+G +++ L PFN + ++++ + R Sbjct: 854 SKRFIGTPDYIAPEVILGNPGI-KASDWWSLGCVVFEFLFGYPPFNAETPDQVFQNILAR 912 Query: 244 KWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAV 280 + + V S+ + + +L+ P +R A+ V Sbjct: 913 RINWPAEVFTAESSVALDLIDRLLCMNPANRLGANGV 949 >SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizosaccharomyces pombe|chr 2|||Manual Length = 953 Score = 55.6 bits (128), Expect = 1e-08 Identities = 59/271 (21%), Positives = 117/271 (43%), Gaps = 33/271 (12%) Query: 25 ILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN- 83 I+++ + EG ++ VY A +++ + V+ P + + E++ + R+ Sbjct: 58 IIQRYLSEGGFSHVYLA--LLENEKPF-----VLKRIYVPDKTALQLVHGEIETMKRLKG 110 Query: 84 HPHIVHV---SNIFQR---RAKYFIFLRFAENGDLLDFLTQN--GAIPENQSRLWMRQII 135 H HIV+ S ++ + R + ++ + F G L+DF+ + E + + + Sbjct: 111 HRHIVNYIDSSALYSKSENRYEVYLLMEFCAGGGLIDFMNTRLQHRLTEGEILKILADVC 170 Query: 136 SGLQYIHTMN--IAHRDLKCENVLVTANYNVKITDFGFA----RNVRQRDRDVLSETYCG 189 + +H ++ + HRDLK ENVL+ A + K+ DFG A D + E Sbjct: 171 DAVAAMHYLDPPLIHRDLKIENVLLVAPNSYKLCDFGSACEPLAPATTPDTIMFLEQNIA 230 Query: 190 SLS---YAAPEV--LKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRK 244 + + Y APE+ + + + +D+W+IGV+ Y + PF + + K Sbjct: 231 AYTTPQYRAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYYTTPFEQVG------NSAILK 284 Query: 245 WRFRTTVVNQLSTECKEQVTQLMEPEPKSRP 275 F + S K + ++ +P RP Sbjct: 285 ASFSFPPFPRYSDRMKRFIATCLQEQPSHRP 315 >SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein kinase Ppk5 |Schizosaccharomyces pombe|chr 1|||Manual Length = 836 Score = 52.8 bits (121), Expect = 7e-08 Identities = 52/195 (26%), Positives = 89/195 (45%), Gaps = 16/195 (8%) Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVI-DTAKAPRDYLTKF-LPRELDVLIRINHPHI 87 +G+GS+ +V K +D R ++A KVI + K L + + + L + ++ Sbjct: 524 VGKGSFGQVLKC---IDHKRGQVVAIKVIKNRQKFHGQTLVEVGILKRLCEADPADKNNV 580 Query: 88 VHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNG--AIPENQSRLWMRQIISGLQYIHTMN 145 + + F R I +L D + +N +P + + Q + L+ + N Sbjct: 581 IRYLSHFDFRGHLCIVTELL-GSNLFDVIRENNYKGLPLIVVKSFALQGLQALRLLQGQN 639 Query: 146 IAHRDLKCENVLVT--ANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203 I H DLK EN+L++ +K+ DFG + ++ TY S Y APE++ G+ Sbjct: 640 IIHCDLKPENLLLSHPLKARIKLIDFGSSCFYNEK-----VYTYLQSRFYRAPEIILGLE 694 Query: 204 YMPKLADMWSIGVIL 218 Y K D+WS G IL Sbjct: 695 Y-GKEIDIWSFGCIL 708 >SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Schizosaccharomyces pombe|chr 1|||Manual Length = 332 Score = 51.2 bits (117), Expect = 2e-07 Identities = 49/207 (23%), Positives = 93/207 (44%), Gaps = 16/207 (7%) Query: 20 QEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVL 79 Q+ I+ KV G G Y++V++ ++++ ++ I K P Y K + RE+ +L Sbjct: 40 QDNYEIIRKV-GRGKYSEVFEGLNVLNNSKCIIKVLK-------PVKY--KKIKREIKIL 89 Query: 80 IRI-NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138 + P+I+ + +I + L F E D +DF T + + R + +++ L Sbjct: 90 QNLAGGPNIISLLDIVRDPESKTPSLIF-EFVDNIDFRTLYPTLSDYDIRYYSYELLKAL 148 Query: 139 QYIHTMNIAHRDLKCENVLVT-ANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197 + H+ I HRD+K NV++ +++ D+G A + S + PE Sbjct: 149 DFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYH---AGMEYNVRVASRYFKGPE 205 Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNK 224 +L D+WS GV+ ++ K Sbjct: 206 LLVDFREYDYSLDIWSFGVMFAALIFK 232 >SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schizosaccharomyces pombe|chr 2|||Manual Length = 749 Score = 49.6 bits (113), Expect = 7e-07 Identities = 59/261 (22%), Positives = 116/261 (44%), Gaps = 30/261 (11%) Query: 66 DYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFL-TQNG---- 120 +Y+ + L +++ L R+ HP ++ V + F+ L DF+ + NG Sbjct: 72 NYVLELLRKDVSSLSRLRHPSLLQVVEPLEESKSSMSFVTRRIQSMLQDFIKSSNGGFSN 131 Query: 121 ------------AIPENQSRLWMRQIISGLQYIH-TMNIAHRDLKCENVLVTANYNVKIT 167 A+ E + + + QII GL ++H + + H +++ +V+V A + K+ Sbjct: 132 YGSSANGKSSGNALEEVEIQKGLLQIIDGLVFLHGSAKVIHYNIRPSSVVVDAKGDWKLC 191 Query: 168 DFGFARNVRQ-----RDRDV-LSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTM 221 F F+++V D D + + S+ + APE + P+ +D++S G ++Y++ Sbjct: 192 GFSFSQSVESARYEFNDYDFGIPSSLQQSMDFLAPEYITHEIAGPE-SDVFSFGCLIYSI 250 Query: 222 LNKALP-FNETSVKKLYEKQV--MRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTAS 278 NK N + YEK++ + F + N S K + + + +PK R + Sbjct: 251 FNKNQSIINANNHLLSYEKEITSLNSPTFIES-KNLPSENLKSLLKETLAVDPKQRASMF 309 Query: 279 AVFNGTWIGMDSRLAKLTFLE 299 + + S +A L FLE Sbjct: 310 ELERSPYF-TGSAIAALRFLE 329 >SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizosaccharomyces pombe|chr 1|||Manual Length = 534 Score = 49.2 bits (112), Expect = 9e-07 Identities = 35/93 (37%), Positives = 50/93 (53%), Gaps = 8/93 (8%) Query: 128 RLWMRQIISGLQYIHTMNIAHRDLKCENVLV--TANYNVKITDFGFARNVRQRDRDVLSE 185 R + Q++S + I H DLK EN+L+ ++ VK+ DFG A + RQ Sbjct: 235 RSFATQLLSCTSLLKQARIIHCDLKPENILLQDLSSPIVKVIDFGSACHERQ-----TVY 289 Query: 186 TYCGSLSYAAPEVLKGVPYMPKLADMWSIGVIL 218 TY S Y +PEV+ G+ Y + DMWS+G IL Sbjct: 290 TYIQSRFYRSPEVILGLHYNCGI-DMWSLGCIL 321 >SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 47.6 bits (108), Expect = 3e-06 Identities = 52/216 (24%), Positives = 93/216 (43%), Gaps = 29/216 (13%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83 + + +++G G++ KV + RH C + T P+ + EL VL I Sbjct: 362 YTVVRLLGHGTFGKVIQCYDQ-STGRH----CAIKVTRAIPKYREASLI--ELRVLQTIA 414 Query: 84 HPHIVHVSNIFQRR-----AKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWM--RQIIS 136 H + + Q R K+ + + DFL N IP + M +Q+ Sbjct: 415 HSDPTNENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKNNNYIPFPLKHIQMLSQQLFK 474 Query: 137 GLQYIHTMNIAHRDLKCENVLVTANYN--VKITDFGFARNV------RQRD------RDV 182 + ++H++ + H DLK ENVL+ +N + +++ +++ V R D D Sbjct: 475 SVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSATFEDE 534 Query: 183 LSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVIL 218 + + Y APE++ G+ + D+WSIG IL Sbjct: 535 YHSSVVSTRHYRAPEIILGLGWSYP-CDVWSIGCIL 569 >SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 46.8 bits (106), Expect = 5e-06 Identities = 47/197 (23%), Positives = 81/197 (41%), Gaps = 27/197 (13%) Query: 102 IFLRFAENGDLLDFLTQNGAIPENQSRLWM--RQIISGLQYIHTMN--IAHRDLKCENVL 157 + L + G L+DFL + ++ + + + +H + + HRDLK ENVL Sbjct: 114 VLLEYCPCGGLIDFLNTRLQVRLSEQEILKIASDVTEAVAVMHYLKPPLIHRDLKIENVL 173 Query: 158 VTANYNVKITDFG----------FARNVRQRDRDVLSETYCGSLSYAAPEVL---KGVPY 204 + A + K+ DFG A +Q + D+ T + Y PE++ KG Sbjct: 174 LAAPNSYKLCDFGSACHPIPGAKTAAEAKQLEYDIEKFT---TWQYRCPEMINVHKGFGI 230 Query: 205 MPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVT 264 K +D+W++GV+ Y + PF + + + F T S K ++ Sbjct: 231 DEK-SDIWALGVLFYKLCYYTTPFEHQGLAAIMNV----SYAFPT--FPPYSDRLKRLIS 283 Query: 265 QLMEPEPKSRPTASAVF 281 L++ P RP F Sbjct: 284 TLLQQYPWQRPNIYQTF 300 >SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosaccharomyces pombe|chr 2|||Manual Length = 365 Score = 46.4 bits (105), Expect = 6e-06 Identities = 36/131 (27%), Positives = 63/131 (48%), Gaps = 12/131 (9%) Query: 133 QIISGLQYIHTMNIAHRDLKCENVLV---TANYNVKITDFGFARNVRQRDRDV-----LS 184 Q+IS +++IH+ + HRD+K +N L+ V I DFG A+ R + + Sbjct: 113 QLISRIEFIHSKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKYRDHKTHLHIPYREN 172 Query: 185 ETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQV 241 + G+ YA+ G+ + D+ S+G +L +LP+ T+ K+ YEK + Sbjct: 173 KNLTGTARYASINTHLGIE-QSRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQKYEKIM 231 Query: 242 MRKWRFRTTVV 252 +K T V+ Sbjct: 232 EKKISTPTEVL 242 >SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1087 Score = 46.0 bits (104), Expect = 8e-06 Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 10/115 (8%) Query: 111 DLLDFLTQNG--AIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANY--NVKI 166 +L + + NG +P + RQ+I L ++ ++ H DLK EN+L+ + VK+ Sbjct: 784 NLYELIKSNGFKGLPIVVIKSITRQLIQCLTLLNEKHVIHCDLKPENILLCHPFKSQVKV 843 Query: 167 TDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTM 221 DFG + + TY S Y +PEV+ G+ Y + D+WS+G I+ M Sbjct: 844 IDFGSSCFEGE-----CVYTYIQSRFYRSPEVILGMGYGTPI-DVWSLGCIIAEM 892 >SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 306 Score = 45.2 bits (102), Expect = 1e-05 Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 4/157 (2%) Query: 78 VLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISG 137 +L I HPHI + + F ++L + +L + +I + + ++ + QI S Sbjct: 59 ILESIGHPHIERIVDSFIDNEAGSVYLITSFKSFVLSDVMDEISI-DTKCKIVL-QISSA 116 Query: 138 LQYIHTMNIAHRDLKCENVLV-TANYNVKITDFGFARNVRQRDRDVLS-ETYCGSLSYAA 195 L+Y+ I HRD+ N+L+ + N ++DF A + + +V G+ Y A Sbjct: 117 LEYLEKHGILHRDIHPNNILLDSMNGPAYLSDFSIAWSKQHPGEEVQELIPQIGTGHYRA 176 Query: 196 PEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETS 232 E L G D W+ G+++ + + F++ S Sbjct: 177 IETLFGCHSYGHEVDRWTFGILIAELFSNQALFDDGS 213 >SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 400 Score = 44.8 bits (101), Expect = 2e-05 Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 7/102 (6%) Query: 133 QIISGLQYIHTMNIAHRDLKCENVLVTANYN-VKITDFGFARNVRQRDRDVL-----SET 186 Q+IS ++Y+H+ + HRD+K +N L+ + N V + DFG A+ R V ++ Sbjct: 114 QLISRIEYVHSKSFLHRDIKPDNFLMKKHSNVVTMIDFGLAKKYRDFKTHVHIPYRDNKN 173 Query: 187 YCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPF 228 G+ YA+ G+ + D+ S+G +L +LP+ Sbjct: 174 LTGTARYASINTHIGIE-QSRRDDLESLGYVLLYFCRGSLPW 214 >SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1072 Score = 44.0 bits (99), Expect = 3e-05 Identities = 23/80 (28%), Positives = 43/80 (53%), Gaps = 11/80 (13%) Query: 133 QIISGLQYIHTMNIAHRDLKCENVLVTAN---------YNVKITDFGFARNVRQRDRDVL 183 QI G+ ++H++++ HRDLK +N+L+ N I+DFG ++ + + Sbjct: 757 QIAFGVSHLHSLDLVHRDLKPQNILLVVNNSPNLSKTRVRALISDFGLSKKLDFNQSSLR 816 Query: 184 SETY--CGSLSYAAPEVLKG 201 + T+ GS + +PE+L G Sbjct: 817 NTTFEAAGSYGWRSPEILSG 836 >SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizosaccharomyces pombe|chr 1|||Manual Length = 344 Score = 41.5 bits (93), Expect = 2e-04 Identities = 41/142 (28%), Positives = 67/142 (47%), Gaps = 14/142 (9%) Query: 148 HRDLKCENVLVTANYN-VKITDFG-------FARNVRQRD--RDVLSETYCGSLSYAAPE 197 H D+K +N+L+ N + +TDFG FA N + +D SE C ++ + APE Sbjct: 192 HGDIKPDNLLLHENSREIVLTDFGSICLVPIFASNNSEAIAIQDKASEN-C-TMPFRAPE 249 Query: 198 V--LKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQL 255 + +K + + AD+WS G LYT++ A PF + + ++ + Sbjct: 250 LFHVKAGSTITEKADIWSFGCTLYTIMFHASPFEREVSQGGSLALAVCNAQYSFPRKHPY 309 Query: 256 STECKEQVTQLMEPEPKSRPTA 277 ST E V ++ EP RP+A Sbjct: 310 STLLCEIVEACLQREPNKRPSA 331 >SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizosaccharomyces pombe|chr 2|||Manual Length = 1706 Score = 41.1 bits (92), Expect = 2e-04 Identities = 49/267 (18%), Positives = 111/267 (41%), Gaps = 24/267 (8%) Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKF--LPRELDVLIRINH 84 E+ +G+ + + ++ M D + ++ ++ K P L+ L +E I Sbjct: 27 ERSLGDSHFLRTFR---MQDRKGYDVLIKVFVN--KLPEISLSSIVNLLKEEQENISYRV 81 Query: 85 PHIV-HVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 P+ V ++ + RA Y + N L D ++ + + + M Q++ G+ H Sbjct: 82 PNAVPYIKTLVTLRAAYLVRPYVTHN--LYDRISTRPFLELTEKKWIMFQLLKGISDCHR 139 Query: 144 MNIAHRDLKCENVLVTANYNVKITDFG-----FARNVRQRDRDVLSETYCGSLSYAAPE- 197 + + H D+K EN+L+T+ ++DF + D +T + APE Sbjct: 140 LGVCHGDIKSENILITSWNWAYLSDFSSFKPTYLPEDNPADYGYFFDTSSRRVCNIAPER 199 Query: 198 -----VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVV 252 L+ P P + D++S+G + +L + P ++ +L+ + + ++ + Sbjct: 200 FVPASQLQPAPLSPAM-DIFSLGCVFAELLLEESPL--FTLSQLFSYKAHGSYDLQSVLE 256 Query: 253 NQLSTECKEQVTQLMEPEPKSRPTASA 279 + + +++ +P R +A A Sbjct: 257 QIEDKSTQNMILSMLDRDPSQRLSADA 283 >SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces pombe|chr 1|||Manual Length = 639 Score = 39.1 bits (87), Expect = 0.001 Identities = 49/191 (25%), Positives = 84/191 (43%), Gaps = 45/191 (23%) Query: 132 RQIISGLQYIHT-MNIAHRDLKCENVLVT------------ANYN----------VKITD 168 R II+G+ Y+H +N+ HRD+K N+ + +YN KI D Sbjct: 398 RMIINGVMYVHEGVNLIHRDIKPSNIFLAKSLPEDRGSVPLISYNDKNDLKEYITPKIGD 457 Query: 169 FGFARNVRQRDRDVLS------------ET-YCGSLSYAAPEVLKGVP----YMPKLADM 211 FG ++ LS ET + G+ +YAAPE+L + K D Sbjct: 458 FGLVVENKKNTETALSFLERNHLPNLQDETQHIGTATYAAPELLDAMSSQHNKFTKKIDT 517 Query: 212 WSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEP 271 +S+G++L+ +L+ PF +T++++ + Q +R+ V Q E + + +P Sbjct: 518 FSLGMVLFELLH---PF-QTNMERATKLQDLRRGNLPEEFVEQHICE-SSLILWMTAKDP 572 Query: 272 KSRPTASAVFN 282 RP+ V N Sbjct: 573 TKRPSLLEVLN 583 >SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosaccharomyces pombe|chr 2|||Manual Length = 429 Score = 36.3 bits (80), Expect = 0.007 Identities = 42/188 (22%), Positives = 81/188 (43%), Gaps = 26/188 (13%) Query: 21 EKGFILEKVIGEGSYAKVYKATHM-VDETRHSIMACKVI------DTAKAPRDYLTKF-- 71 E+ + + K++G GS++ V+KA D +S I D K P+++ Sbjct: 37 EEDYHVVKLVGAGSFSSVFKAVDRHFDSYDNSYWISSQIEDQMPHDKTKRPKNHFVALKR 96 Query: 72 -----LPRELDVLIRINHPH-----IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGA 121 LP + + + H ++++ + + + I L F ++ + DF + + Sbjct: 97 IYATVLPSRIQTELEMLHELRGSDCVLNMITAVRHQDQVLIVLPFIQHAEFRDFYMKY-S 155 Query: 122 IPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTA-NYNVKITDFGFARNVRQRDR 180 +PE + ++R ++ GL +I I HRD+K N I DFG A + ++ Sbjct: 156 LPEIGA--YLRDLLKGLAHIDAKGIIHRDIKPGNFAWNPYTQRGVILDFGLA---QWQEA 210 Query: 181 DVLSETYC 188 D +E C Sbjct: 211 DAPTENCC 218 Score = 33.5 bits (73), Expect = 0.047 Identities = 16/40 (40%), Positives = 20/40 (50%) Query: 189 GSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPF 228 G+ + APEVL D+WS+GVIL L PF Sbjct: 263 GTRGFRAPEVLFRCQNQTSSIDVWSVGVILLCFLTHRYPF 302 >SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 665 Score = 36.3 bits (80), Expect = 0.007 Identities = 27/117 (23%), Positives = 50/117 (42%), Gaps = 2/117 (1%) Query: 70 KFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRL 129 + L EL L ++H +++ + F + + + L L E Sbjct: 428 RLLLEELQRLSGLSHKNLIRYNESFWYLNNIWSVFEYKDPSTKLSALIPKYFFSELNIAS 487 Query: 130 WMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNV--RQRDRDVLS 184 +I SGL ++H IAH +L E + +T + +KI ++ F+ RQ +R +S Sbjct: 488 ICYEISSGLAFLHNSGIAHHNLTTECIYLTKSSCLKIGNYAFSSPYIERQTNRGAVS 544 >SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizosaccharomyces pombe|chr 2|||Manual Length = 435 Score = 34.7 bits (76), Expect = 0.020 Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 5/50 (10%) Query: 132 RQIISGLQYIHTMNIAHRDLKCENVLV----TANYN-VKITDFGFARNVR 176 +Q++S +Q IH N+ +RD+K +N L+ + N N V + DFG A+ R Sbjct: 113 KQMLSRVQTIHEKNLVYRDIKPDNFLIGRPSSRNANMVYMVDFGMAKYYR 162 >SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 507 Score = 33.9 bits (74), Expect = 0.036 Identities = 21/43 (48%), Positives = 26/43 (60%), Gaps = 3/43 (6%) Query: 189 GSLSYAAPEVL-KGVPYMPKLADMWSIGVILYTMLNKALP-FN 229 G+ + APEVL K PK+ D+WS GVIL + L K P FN Sbjct: 290 GTRGFRAPEVLFKCSSQSPKV-DIWSAGVILLSFLTKRFPMFN 331 Score = 31.5 bits (68), Expect = 0.19 Identities = 34/159 (21%), Positives = 63/159 (39%), Gaps = 13/159 (8%) Query: 25 ILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINH 84 I +V+ E S+ K K D + +A K I +P + EL++L + Sbjct: 99 IQSEVLKESSFGKE-KIPVNEDSRKPKYVAIKKIYATSSPAR-----IYNELEILYLLRG 152 Query: 85 PHIVH-VSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143 ++ + + + + L + E+ D + + ++ R + +Q T Sbjct: 153 SSVIAPLITALRNEDQVLVVLPYYEHTDFRQYYS---TFSYRDMSIYFRCLFQAMQQTQT 209 Query: 144 MNIAHRDLKCENVL--VTANYNVKITDFGFARNVRQRDR 180 + I HRD+K N L V + V + DFG A R + Sbjct: 210 LGIIHRDIKPSNFLFDVRTKHGV-LVDFGLAERYDGRQQ 247 >SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 544 Score = 30.7 bits (66), Expect = 0.33 Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 15/146 (10%) Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLP-----RELDV 78 +++E+ +G G ++ V+ A + R +A KV+ +A+ R+ + RE D Sbjct: 81 YVVERKLGWGHFSTVWLAYDRAAKRR---VALKVVRSAEHYRETSIDEIRILQKIREGDE 137 Query: 79 LIRINHPHIVHVSNIFQRRAKY--FIFLRFAENGD-LLDFLTQNG--AIPENQSRLWMRQ 133 + HI+ + + F R + + F G+ LL + G +P + Q Sbjct: 138 K-HLGKKHIISLLDYFVHRGPNGAHVCMVFEVLGENLLSLIQSYGHRGVPVGIVKQIAYQ 196 Query: 134 IISGLQYIHT-MNIAHRDLKCENVLV 158 ++ L Y+H I H DLK ENVL+ Sbjct: 197 LLIALDYLHRECGIIHTDLKPENVLI 222 >SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces pombe|chr 1|||Manual Length = 704 Score = 30.3 bits (65), Expect = 0.44 Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 6/62 (9%) Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKF-LPRELDVLIRINHPH 86 +++G+G Y VYKA + D +++ + R + T + RE L R+NHP+ Sbjct: 228 ELLGKGGYGSVYKARNKFDGVEYALKKIPL-----RLRSFSTSSNIFRESRTLARLNHPN 282 Query: 87 IV 88 ++ Sbjct: 283 VI 284 Score = 29.9 bits (64), Expect = 0.58 Identities = 12/33 (36%), Positives = 22/33 (66%), Gaps = 1/33 (3%) Query: 129 LWMRQIISGLQYIH-TMNIAHRDLKCENVLVTA 160 L +I+ G+ Y+H M++ HRDLK N+ +++ Sbjct: 469 LLFARILEGVLYLHDAMHLVHRDLKPRNIFLSS 501 >SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizosaccharomyces pombe|chr 2|||Manual Length = 446 Score = 29.9 bits (64), Expect = 0.58 Identities = 15/50 (30%), Positives = 30/50 (60%), Gaps = 5/50 (10%) Query: 132 RQIISGLQYIHTMNIAHRDLKCENVLV----TANYN-VKITDFGFARNVR 176 +Q+++ +Q IH ++ +RD+K +N L+ + N N + + DFG + R Sbjct: 113 KQMLARVQSIHEKSLVYRDIKPDNFLIGRPNSKNANMIYVVDFGMVKFYR 162 >SPBC2D10.13 |est1||telomerase regulator Est1|Schizosaccharomyces pombe|chr 2|||Manual Length = 490 Score = 28.7 bits (61), Expect = 1.3 Identities = 13/34 (38%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 50 HSIMAC-KVIDTAKAPRDYLTKFLPRELDVLIRI 82 H +AC K +++ +AP YLT LP +L R+ Sbjct: 357 HQTLACAKEVESERAPTSYLTSCLPSIKVILARV 390 >SPCC63.05 |||TAP42 family protein |Schizosaccharomyces pombe|chr 3|||Manual Length = 323 Score = 28.3 bits (60), Expect = 1.8 Identities = 14/35 (40%), Positives = 21/35 (60%) Query: 298 LEESLLKQAHEESQKRDNSTEEDSEVERIAELRRK 332 +E LLK+A E K ++S E+D E R E ++K Sbjct: 175 MEIDLLKRAQAELMKSEDSPEKDEETLRREERKQK 209 >SPAC17D4.04 ||SPAC458.01|tRNA |Schizosaccharomyces pombe|chr 1|||Manual Length = 654 Score = 28.3 bits (60), Expect = 1.8 Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Query: 297 FLEESLLKQAHEESQKRDNSTEEDSEVERIAELRRKGR 334 FL E L + + S+KR T+E S ++AE++ KG+ Sbjct: 418 FLREQKLP-SEQASKKRKQDTQETSSDSKLAEVKPKGK 454 >SPAC3A12.13c |||translation initiation factor eIF3 complex subunit|Schizosaccharomyces pombe|chr 1|||Manual Length = 274 Score = 27.9 bits (59), Expect = 2.3 Identities = 13/49 (26%), Positives = 27/49 (55%) Query: 299 EESLLKQAHEESQKRDNSTEEDSEVERIAELRRKGRGKEGLKVLKNVDA 347 +ESL +H SQK +S++ D ++ +++K + + K +K +A Sbjct: 48 KESLQNDSHSVSQKSSSSSQNDQGSNKMTRIQQKIQERNFEKAIKASEA 96 >SPBC15D4.01c ||SPBC2D10.21c|kinesin-like protein|Schizosaccharomyces pombe|chr 2|||Manual Length = 633 Score = 27.5 bits (58), Expect = 3.1 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 14/109 (12%) Query: 45 VDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFL 104 V+ R + CK+++ +K +L P LD+ + + H I ++ +Y I+L Sbjct: 135 VEFLRSQLEKCKIVEASK----FLRGEAP--LDIKVPNTEYYASHFPKIEEKNYQYAIYL 188 Query: 105 RFAE--NG---DLLD---FLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145 FAE N DLL+ F A+ +S ++ I+G+Q + N Sbjct: 189 SFAEIYNDRIFDLLEKASFFGHRHALSLKKSSTSDKKSIAGIQKVFVSN 237 >SPCC74.06 |mak3|phk2|histidine kinase Mak3 |Schizosaccharomyces pombe|chr 3|||Manual Length = 2344 Score = 27.1 bits (57), Expect = 4.1 Identities = 23/111 (20%), Positives = 54/111 (48%), Gaps = 15/111 (13%) Query: 138 LQYIHTMNIAHRDLKCENVLVTANY-NVKITDFGF----------ARNVRQRDRDVLSET 186 ++Y+H+ + H +++ ++ + ++Y NV + G A N R+ D SE+ Sbjct: 136 IEYLHSKGMVHGEIRLDSFIPISSYDNVYMLTVGSGASYFHNCLQAHNWRKYSED--SES 193 Query: 187 YCGSLSYAAPEVLKGVPY-MPKLADMWSIGVILYTMLNKALPFNETSVKKL 236 + + +PE Y + D++S+GV+ + L+ P+ + V+++ Sbjct: 194 -MSRILFISPEQTGRTSYSVGYRTDIYSLGVLFFHYLSDCSPYTGSFVQRI 243 >SPAC1B1.04c |||poly|Schizosaccharomyces pombe|chr 1|||Manual Length = 604 Score = 27.1 bits (57), Expect = 4.1 Identities = 13/52 (25%), Positives = 26/52 (50%) Query: 133 QIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLS 184 Q+IS L IH+ +A + + +NVL+ + I G +++ + L+ Sbjct: 344 QLISALYSIHSSGLAAKMVSLKNVLMVGKMRLAIFGLGIMDVIQEESTEPLT 395 >SPBC336.14c |ppk26||serine/threonine protein kinase Ppk26|Schizosaccharomyces pombe|chr 2|||Manual Length = 589 Score = 27.1 bits (57), Expect = 4.1 Identities = 14/52 (26%), Positives = 23/52 (44%) Query: 116 LTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKIT 167 L +N IPE + + Q+ L Y+H A L +LV ++I+ Sbjct: 324 LEENRKIPERELWNYFFQLTIALSYLHKSGFACNKLTPSRILVDQTERIRIS 375 >SPAC343.04c |gnr1||heterotrimeric G protein beta subunit Gnr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 507 Score = 27.1 bits (57), Expect = 4.1 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 11/92 (11%) Query: 256 STECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLKQAHEESQKRDN 315 S + E+ T L+ + AV G WI ++ + + +ES K+A QK Sbjct: 27 SLKALEKETGLVSETEDVKRLKQAVLQGDWITAEAAFSIMQLRDESKRKEAQFLLQK--- 83 Query: 316 STEEDSEVERIAELRRKGRGKEGLKVLKNVDA 347 +R EL R G E + VL+N ++ Sbjct: 84 --------QRCLELARSGAICEAIYVLQNFES 107 >SPAC144.05 |||ATP-dependent DNA helicase|Schizosaccharomyces pombe|chr 1|||Manual Length = 1375 Score = 26.2 bits (55), Expect = 7.2 Identities = 11/39 (28%), Positives = 23/39 (58%) Query: 44 MVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82 + + R IM+ +I T+K ++ KF+P++L + R+ Sbjct: 721 LAQDLRRKIMSDVIIKTSKHLEEFSEKFIPKKLVKIPRL 759 >SPAC29A4.09 |||rRNA processing protein Rrp17|Schizosaccharomyces pombe|chr 1|||Manual Length = 203 Score = 26.2 bits (55), Expect = 7.2 Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 2/37 (5%) Query: 294 KLTFLEE--SLLKQAHEESQKRDNSTEEDSEVERIAE 328 +L F +E S L+ E SQ+ D+S++ DSE E E Sbjct: 82 RLAFSKELNSSLENDEESSQQEDSSSKSDSEEESSME 118 >SPAC1782.09c |clp1|flp1|Cdc14-related protein phosphatase Clp1/Flp1|Schizosaccharomyces pombe|chr 1|||Manual Length = 537 Score = 26.2 bits (55), Expect = 7.2 Identities = 13/40 (32%), Positives = 21/40 (52%) Query: 304 KQAHEESQKRDNSTEEDSEVERIAELRRKGRGKEGLKVLK 343 KQ+ + K S+ EDSE++ E R G E + V++ Sbjct: 423 KQSIQNENKASYSSYEDSEIQNDDETRTVGTPTETISVVR 462 >SPAC1952.02 |||ribosome biogenesis protein|Schizosaccharomyces pombe|chr 1|||Manual Length = 202 Score = 25.8 bits (54), Expect = 9.5 Identities = 11/47 (23%), Positives = 29/47 (61%) Query: 288 MDSRLAKLTFLEESLLKQAHEESQKRDNSTEEDSEVERIAELRRKGR 334 +DS ++ ++ + + K + +ES KR+ S ++ + E+ +L++K + Sbjct: 116 LDSSVSPVSSKKVKVRKTSGKESSKREKSKKKKEKKEKKDKLKKKSK 162 >SPAC11G7.06c |mug132||S. pombe specific UPF0300 family protein 3|Schizosaccharomyces pombe|chr 1|||Manual Length = 430 Score = 25.8 bits (54), Expect = 9.5 Identities = 14/35 (40%), Positives = 19/35 (54%) Query: 93 IFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQS 127 IF+RR+KYF R +G L +L +I N S Sbjct: 269 IFRRRSKYFNLARSCVSGFELSWLIMMTSIGSNAS 303 >SPAC16E8.12c |||sequence orphan|Schizosaccharomyces pombe|chr 1|||Manual Length = 170 Score = 25.8 bits (54), Expect = 9.5 Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 1/37 (2%) Query: 91 SNIFQRRAKYFIFLRFA-ENGDLLDFLTQNGAIPENQ 126 +N+ RRAK + A E GD +T +G +PE + Sbjct: 102 ANLRNRRAKELLAAENASEEGDKKQIITDSGKLPETE 138 Database: spombe Posted date: Oct 3, 2007 3:31 PM Number of letters in database: 2,362,478 Number of sequences in database: 5004 Lambda K H 0.319 0.134 0.387 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,624,271 Number of Sequences: 5004 Number of extensions: 67886 Number of successful extensions: 495 Number of sequences better than 10.0: 117 Number of HSP's better than 10.0 without gapping: 105 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 214 Number of HSP's gapped (non-prelim): 147 length of query: 360 length of database: 2,362,478 effective HSP length: 74 effective length of query: 286 effective length of database: 1,992,182 effective search space: 569764052 effective search space used: 569764052 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.8 bits) S2: 54 (25.8 bits)
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