Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001013-TA|BGIBMGA001013-PA|IPR002290|Serine/threonine
protein kinase, IPR000719|Protein kinase, IPR008271|Serine/threonine
protein kinase, active site, IPR001245|Tyrosine protein kinase,
IPR011009|Protein kinase-like
(360 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 220 5e-57
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 220 5e-57
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 220 5e-57
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 220 7e-57
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 220 7e-57
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 220 7e-57
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 220 7e-57
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 206 9e-53
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 206 9e-53
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 206 9e-53
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 202 1e-51
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 202 1e-51
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 202 1e-51
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 202 1e-51
AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens ... 194 3e-49
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 191 4e-48
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 172 2e-42
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 172 2e-42
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 172 2e-42
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 172 2e-42
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 172 2e-42
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 172 2e-42
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 172 2e-42
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 172 2e-42
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 172 2e-42
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 171 2e-42
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 171 2e-42
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 171 2e-42
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 171 2e-42
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 171 2e-42
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 171 2e-42
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 171 2e-42
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 171 2e-42
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 171 3e-42
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 171 4e-42
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 171 4e-42
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 171 4e-42
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 171 4e-42
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 169 1e-41
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 169 1e-41
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 168 3e-41
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 168 3e-41
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 167 4e-41
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 167 4e-41
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 167 4e-41
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 165 3e-40
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 163 1e-39
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 163 1e-39
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 161 3e-39
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 161 3e-39
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 161 3e-39
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 161 3e-39
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 161 3e-39
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 161 3e-39
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 161 3e-39
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 161 3e-39
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 158 2e-38
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 158 2e-38
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 158 2e-38
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 158 2e-38
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 158 2e-38
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 155 2e-37
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 155 2e-37
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 153 7e-37
BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein. 153 1e-36
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 153 1e-36
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 153 1e-36
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 153 1e-36
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 153 1e-36
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 153 1e-36
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 153 1e-36
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 150 6e-36
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 150 9e-36
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 150 9e-36
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 150 9e-36
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 150 9e-36
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 150 9e-36
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 150 9e-36
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 147 6e-35
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 146 8e-35
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 145 2e-34
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 144 4e-34
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 144 4e-34
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 144 6e-34
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 144 6e-34
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 144 6e-34
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 144 6e-34
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 143 7e-34
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 143 7e-34
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 143 7e-34
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 143 7e-34
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 143 7e-34
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 143 1e-33
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 142 1e-33
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 140 7e-33
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 138 3e-32
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 138 3e-32
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 138 3e-32
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 138 3e-32
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 136 1e-31
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 136 1e-31
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 136 1e-31
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 136 1e-31
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 136 1e-31
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 136 1e-31
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 135 2e-31
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 135 3e-31
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 135 3e-31
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 135 3e-31
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 135 3e-31
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 135 3e-31
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 134 3e-31
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 134 3e-31
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 134 3e-31
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 134 3e-31
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 134 3e-31
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 134 3e-31
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 134 3e-31
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 134 3e-31
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 134 3e-31
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 134 3e-31
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 134 3e-31
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 134 3e-31
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 132 1e-30
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 132 2e-30
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 132 2e-30
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 132 2e-30
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 132 2e-30
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 132 2e-30
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 132 2e-30
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 131 3e-30
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 131 3e-30
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 131 4e-30
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 131 4e-30
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 130 7e-30
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 130 1e-29
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 130 1e-29
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 130 1e-29
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 130 1e-29
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 130 1e-29
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 130 1e-29
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 130 1e-29
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 130 1e-29
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 130 1e-29
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 130 1e-29
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 128 3e-29
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 128 4e-29
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 128 4e-29
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 127 5e-29
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 127 5e-29
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 127 5e-29
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 127 5e-29
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 127 5e-29
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 127 7e-29
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 127 7e-29
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 127 7e-29
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 127 7e-29
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 127 7e-29
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 127 7e-29
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 127 7e-29
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 127 7e-29
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 127 7e-29
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 127 7e-29
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 127 7e-29
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 127 7e-29
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 127 7e-29
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 127 7e-29
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 127 7e-29
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 127 7e-29
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 126 9e-29
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 126 9e-29
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 126 9e-29
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 126 9e-29
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 126 9e-29
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 126 9e-29
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 126 9e-29
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 126 9e-29
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 126 9e-29
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 126 9e-29
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 126 9e-29
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 126 9e-29
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 126 9e-29
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 126 9e-29
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 126 9e-29
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 126 9e-29
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 126 9e-29
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 126 9e-29
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 126 9e-29
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 126 9e-29
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 126 9e-29
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 126 9e-29
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 126 9e-29
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 126 1e-28
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 126 2e-28
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 126 2e-28
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 126 2e-28
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 126 2e-28
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 126 2e-28
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 126 2e-28
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 126 2e-28
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 126 2e-28
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 126 2e-28
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 125 2e-28
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 125 2e-28
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 125 3e-28
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 125 3e-28
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 124 4e-28
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 124 4e-28
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 124 4e-28
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 124 4e-28
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 124 4e-28
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 124 5e-28
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 124 6e-28
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 123 8e-28
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 123 8e-28
BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6 ki... 123 8e-28
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 123 8e-28
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 123 8e-28
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 123 8e-28
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 123 8e-28
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 123 8e-28
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 123 8e-28
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 123 8e-28
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 123 8e-28
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 123 8e-28
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 123 8e-28
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 123 8e-28
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 123 8e-28
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 123 8e-28
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 123 8e-28
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 123 8e-28
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 123 1e-27
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 123 1e-27
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 123 1e-27
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 123 1e-27
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 123 1e-27
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 123 1e-27
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 123 1e-27
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 123 1e-27
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 123 1e-27
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 123 1e-27
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 123 1e-27
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 123 1e-27
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 123 1e-27
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 123 1e-27
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 123 1e-27
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 123 1e-27
BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein. 122 1e-27
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 122 2e-27
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 122 2e-27
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 122 2e-27
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 122 2e-27
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 122 2e-27
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 122 2e-27
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 122 2e-27
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 122 2e-27
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 122 2e-27
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 122 2e-27
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 122 2e-27
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 122 2e-27
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 122 2e-27
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 122 2e-27
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 122 2e-27
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 122 2e-27
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 122 2e-27
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 122 3e-27
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 122 3e-27
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 122 3e-27
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 122 3e-27
Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 121 3e-27
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 121 3e-27
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 121 3e-27
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 121 3e-27
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 121 3e-27
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 121 3e-27
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 121 3e-27
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 121 3e-27
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 121 5e-27
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 121 5e-27
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 121 5e-27
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 120 6e-27
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 120 6e-27
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 120 6e-27
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 120 6e-27
Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 120 8e-27
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 120 8e-27
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 120 8e-27
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 120 1e-26
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 120 1e-26
BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing s... 120 1e-26
BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein. 120 1e-26
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 120 1e-26
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 120 1e-26
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 120 1e-26
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 120 1e-26
AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein. 120 1e-26
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 120 1e-26
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 119 1e-26
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 119 1e-26
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 119 1e-26
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 119 1e-26
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 119 1e-26
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 119 1e-26
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 119 1e-26
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 119 1e-26
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 119 1e-26
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 119 1e-26
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 119 1e-26
U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein ... 119 2e-26
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 119 2e-26
BC019256-1|AAH19256.1| 501|Homo sapiens CaM kinase-like vesicle... 119 2e-26
BC017363-1|AAH17363.1| 501|Homo sapiens CaM kinase-like vesicle... 119 2e-26
BC005828-1|AAH05828.1| 501|Homo sapiens CaM kinase-like vesicle... 119 2e-26
BC001921-1|AAH01921.1| 501|Homo sapiens CaM kinase-like vesicle... 119 2e-26
BC000497-1|AAH00497.1| 501|Homo sapiens CaM kinase-like vesicle... 119 2e-26
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 119 2e-26
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 119 2e-26
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 119 2e-26
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 119 2e-26
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 119 2e-26
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 119 2e-26
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 119 2e-26
AK075294-1|BAC11528.1| 470|Homo sapiens protein ( Homo sapiens ... 119 2e-26
AK074899-1|BAC11278.1| 470|Homo sapiens protein ( Homo sapiens ... 119 2e-26
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 119 2e-26
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 119 2e-26
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 119 2e-26
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 119 2e-26
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 118 2e-26
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 118 2e-26
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 118 2e-26
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 118 2e-26
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 118 2e-26
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 118 2e-26
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 118 2e-26
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 118 3e-26
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 118 3e-26
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 118 3e-26
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 118 3e-26
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 118 3e-26
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 118 3e-26
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 118 4e-26
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 118 4e-26
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 118 4e-26
U42390-1|AAC34245.1| 2861|Homo sapiens Trio protein. 117 6e-26
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 117 6e-26
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 117 6e-26
BC017268-1|AAH17268.1| 383|Homo sapiens TRIO protein protein. 117 6e-26
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 117 6e-26
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 117 6e-26
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 117 6e-26
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 117 6e-26
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 117 6e-26
AK131423-1|BAD18570.1| 596|Homo sapiens protein ( Homo sapiens ... 117 6e-26
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 117 6e-26
AF091395-1|AAC43042.1| 3038|Homo sapiens Trio isoform protein. 117 6e-26
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 117 6e-26
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 117 6e-26
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 117 7e-26
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 117 7e-26
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 117 7e-26
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 117 7e-26
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 117 7e-26
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 117 7e-26
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 117 7e-26
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 117 7e-26
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 117 7e-26
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 117 7e-26
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 117 7e-26
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 117 7e-26
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 116 1e-25
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 116 1e-25
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 116 1e-25
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 116 1e-25
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 116 1e-25
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 116 1e-25
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 116 1e-25
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 116 1e-25
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 116 1e-25
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 116 1e-25
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 116 1e-25
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 116 1e-25
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 116 2e-25
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 116 2e-25
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 116 2e-25
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 116 2e-25
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 116 2e-25
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 116 2e-25
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 116 2e-25
AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase... 116 2e-25
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 115 2e-25
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 115 2e-25
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 115 2e-25
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 115 2e-25
BC117311-1|AAI17312.1| 898|Homo sapiens CASK protein protein. 115 3e-25
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 115 3e-25
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 115 3e-25
AY705392-1|AAU10527.1| 921|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL627402-6|CAH71241.1| 590|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL627402-5|CAH71238.1| 897|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL627402-4|CAH71237.1| 909|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL627402-3|CAH71240.1| 926|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL627402-2|CAH71239.1| 921|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL603754-6|CAI41638.1| 590|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL603754-5|CAI41635.1| 926|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL603754-4|CAI41636.1| 921|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL603754-3|CAI41637.1| 897|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL603754-2|CAI41634.1| 909|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL445239-7|CAI41096.1| 590|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL445239-6|CAI41093.1| 926|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL445239-5|CAI41094.1| 921|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL445239-4|CAI41095.1| 897|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL445239-3|CAI41092.1| 909|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL353691-7|CAI42248.1| 590|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL353691-6|CAI42245.1| 926|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL353691-5|CAI42246.1| 921|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL353691-4|CAI42247.1| 897|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL353691-3|CAI42244.1| 909|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL158144-5|CAI42766.1| 590|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL158144-4|CAI42763.1| 926|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL158144-3|CAI42764.1| 921|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL158144-2|CAI42765.1| 897|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL158144-1|CAI42762.1| 909|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AF035582-1|AAB88198.1| 897|Homo sapiens CASK protein. 115 3e-25
AF032119-1|AAB88125.1| 921|Homo sapiens hCASK protein. 115 3e-25
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 114 4e-25
AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 ki... 114 4e-25
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 114 5e-25
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 114 5e-25
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 114 5e-25
AK074856-1|BAC11248.1| 501|Homo sapiens protein ( Homo sapiens ... 114 5e-25
AB208859-1|BAD92096.1| 917|Homo sapiens calcium/calmodulin-depe... 114 5e-25
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 113 7e-25
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 113 7e-25
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 113 7e-25
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 113 7e-25
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 113 7e-25
BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein. 113 7e-25
BC028079-1|AAH28079.1| 556|Homo sapiens Unknown (protein for IM... 113 7e-25
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 113 7e-25
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 113 7e-25
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 113 7e-25
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 113 7e-25
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 113 7e-25
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 113 7e-25
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 113 7e-25
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 113 9e-25
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 113 9e-25
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 113 9e-25
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 113 9e-25
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 113 1e-24
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 113 1e-24
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 113 1e-24
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 113 1e-24
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 113 1e-24
AL713896-5|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AL713896-3|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AL713896-2|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AL596247-5|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AL596247-3|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AL596247-2|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 113 1e-24
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 113 1e-24
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 112 2e-24
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 112 2e-24
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 111 3e-24
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 111 3e-24
D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein. 111 3e-24
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 111 3e-24
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 111 3e-24
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 111 3e-24
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 111 4e-24
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 111 4e-24
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 111 4e-24
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 111 4e-24
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 111 4e-24
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 111 4e-24
AF542390-1|AAN62841.1| 258|Homo sapiens AT03158-like protein pr... 111 5e-24
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 111 5e-24
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 111 5e-24
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 111 5e-24
AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human seri... 111 5e-24
AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein. 111 5e-24
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 111 5e-24
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 110 6e-24
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 110 6e-24
AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kina... 110 6e-24
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 110 8e-24
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 110 8e-24
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 109 1e-23
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 109 1e-23
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 109 1e-23
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 109 1e-23
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 109 1e-23
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 109 1e-23
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 109 1e-23
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 109 1e-23
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 109 1e-23
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 220 bits (538), Expect = 5e-57
Identities = 105/280 (37%), Positives = 177/280 (63%), Gaps = 8/280 (2%)
Query: 15 DIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR 74
D AVL+ +G++L +GEGSYAKV A E +A K+ID KAP D+L KFLPR
Sbjct: 3 DAAVLKRRGYLLGINLGEGSYAKVKSA---YSERLKFNVAIKIIDRKKAPADFLEKFLPR 59
Query: 75 ELDVLIRINHPHIVHVSNIFQR-RAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQ 133
E+++L +NH I+ IF+ K +I + A GDLL+ + GA+ E+++R Q
Sbjct: 60 EIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQ 119
Query: 134 IISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRD--RDVLSETYCGSL 191
+ ++Y H +++ HRDLKC+N+L+ ++N+K++DF F++ + D R LS+T+CGS
Sbjct: 120 LSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSP 179
Query: 192 SYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
+YAAPEVL+G+PY PK+ D+WS+GVILY M+ ++P++++++KK+ ++ ++ R
Sbjct: 180 AYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKML--RIQKEHRVNFPR 237
Query: 252 VNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSR 291
L+ ECK+ + +++P+ R + + W+ +R
Sbjct: 238 SKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKAR 277
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 220 bits (538), Expect = 5e-57
Identities = 105/280 (37%), Positives = 177/280 (63%), Gaps = 8/280 (2%)
Query: 15 DIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR 74
D AVL+ +G++L +GEGSYAKV A E +A K+ID KAP D+L KFLPR
Sbjct: 3 DAAVLKRRGYLLGINLGEGSYAKVKSA---YSERLKFNVAIKIIDRKKAPADFLEKFLPR 59
Query: 75 ELDVLIRINHPHIVHVSNIFQR-RAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQ 133
E+++L +NH I+ IF+ K +I + A GDLL+ + GA+ E+++R Q
Sbjct: 60 EIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQ 119
Query: 134 IISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRD--RDVLSETYCGSL 191
+ ++Y H +++ HRDLKC+N+L+ ++N+K++DF F++ + D R LS+T+CGS
Sbjct: 120 LSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSP 179
Query: 192 SYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
+YAAPEVL+G+PY PK+ D+WS+GVILY M+ ++P++++++KK+ ++ ++ R
Sbjct: 180 AYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKML--RIQKEHRVNFPR 237
Query: 252 VNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSR 291
L+ ECK+ + +++P+ R + + W+ +R
Sbjct: 238 SKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKAR 277
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 220 bits (538), Expect = 5e-57
Identities = 105/280 (37%), Positives = 177/280 (63%), Gaps = 8/280 (2%)
Query: 15 DIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR 74
D AVL+ +G++L +GEGSYAKV A E +A K+ID KAP D+L KFLPR
Sbjct: 3 DAAVLKRRGYLLGINLGEGSYAKVKSA---YSERLKFNVAIKIIDRKKAPADFLEKFLPR 59
Query: 75 ELDVLIRINHPHIVHVSNIFQR-RAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQ 133
E+++L +NH I+ IF+ K +I + A GDLL+ + GA+ E+++R Q
Sbjct: 60 EIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQ 119
Query: 134 IISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRD--RDVLSETYCGSL 191
+ ++Y H +++ HRDLKC+N+L+ ++N+K++DF F++ + D R LS+T+CGS
Sbjct: 120 LSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSP 179
Query: 192 SYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
+YAAPEVL+G+PY PK+ D+WS+GVILY M+ ++P++++++KK+ ++ ++ R
Sbjct: 180 AYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKML--RIQKEHRVNFPR 237
Query: 252 VNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSR 291
L+ ECK+ + +++P+ R + + W+ +R
Sbjct: 238 SKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKAR 277
>CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein.
Length = 358
Score = 220 bits (537), Expect = 7e-57
Identities = 102/275 (37%), Positives = 176/275 (64%), Gaps = 8/275 (2%)
Query: 15 DIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR 74
D VL++KG+I+ +G+GSYAKV A E +A K+ID K P D++ +FLPR
Sbjct: 3 DATVLRKKGYIVGINLGKGSYAKVKSA---YSERLKFNVAVKIIDRKKTPTDFVERFLPR 59
Query: 75 ELDVLIRINHPHIVHVSNIFQRR-AKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQ 133
E+D+L +NH I+ IF+ + +I + GDLL+F+ GA+ E+ +R RQ
Sbjct: 60 EMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQ 119
Query: 134 IISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQ--RDRDVLSETYCGSL 191
+ S ++Y H ++I HRDLKCEN+L+ ++N+K++DFGF++ + R +LS+T+CGS
Sbjct: 120 LSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSA 179
Query: 192 SYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
+YAAPEVL+ +PY PK+ D+WS+GVILY M+ ++P++++ ++K+ ++ ++ R
Sbjct: 180 AYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKML--RIQKEHRVDFPR 237
Query: 252 VNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
L+ ECK+ + ++++P+ R + + +W+
Sbjct: 238 SKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL 272
>BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 220 bits (537), Expect = 7e-57
Identities = 102/275 (37%), Positives = 176/275 (64%), Gaps = 8/275 (2%)
Query: 15 DIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR 74
D VL++KG+I+ +G+GSYAKV A E +A K+ID K P D++ +FLPR
Sbjct: 3 DATVLRKKGYIVGINLGKGSYAKVKSA---YSERLKFNVAVKIIDRKKTPTDFVERFLPR 59
Query: 75 ELDVLIRINHPHIVHVSNIFQRR-AKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQ 133
E+D+L +NH I+ IF+ + +I + GDLL+F+ GA+ E+ +R RQ
Sbjct: 60 EMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQ 119
Query: 134 IISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQ--RDRDVLSETYCGSL 191
+ S ++Y H ++I HRDLKCEN+L+ ++N+K++DFGF++ + R +LS+T+CGS
Sbjct: 120 LSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSA 179
Query: 192 SYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
+YAAPEVL+ +PY PK+ D+WS+GVILY M+ ++P++++ ++K+ ++ ++ R
Sbjct: 180 AYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKML--RIQKEHRVDFPR 237
Query: 252 VNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
L+ ECK+ + ++++P+ R + + +W+
Sbjct: 238 SKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL 272
>AF362953-1|AAK98531.1| 358|Homo sapiens testis specific
serine/threonine kinase 2 protein.
Length = 358
Score = 220 bits (537), Expect = 7e-57
Identities = 102/275 (37%), Positives = 176/275 (64%), Gaps = 8/275 (2%)
Query: 15 DIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR 74
D VL++KG+I+ +G+GSYAKV A E +A K+ID K P D++ +FLPR
Sbjct: 3 DATVLRKKGYIVGINLGKGSYAKVKSA---YSERLKFNVAVKIIDRKKTPTDFVERFLPR 59
Query: 75 ELDVLIRINHPHIVHVSNIFQRR-AKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQ 133
E+D+L +NH I+ IF+ + +I + GDLL+F+ GA+ E+ +R RQ
Sbjct: 60 EMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQ 119
Query: 134 IISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQ--RDRDVLSETYCGSL 191
+ S ++Y H ++I HRDLKCEN+L+ ++N+K++DFGF++ + R +LS+T+CGS
Sbjct: 120 LSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSA 179
Query: 192 SYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
+YAAPEVL+ +PY PK+ D+WS+GVILY M+ ++P++++ ++K+ ++ ++ R
Sbjct: 180 AYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKML--RIQKEHRVDFPR 237
Query: 252 VNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
L+ ECK+ + ++++P+ R + + +W+
Sbjct: 238 SKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL 272
>AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 220 bits (537), Expect = 7e-57
Identities = 102/275 (37%), Positives = 176/275 (64%), Gaps = 8/275 (2%)
Query: 15 DIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR 74
D VL++KG+I+ +G+GSYAKV A E +A K+ID K P D++ +FLPR
Sbjct: 3 DATVLRKKGYIVGINLGKGSYAKVKSA---YSERLKFNVAVKIIDRKKTPTDFVERFLPR 59
Query: 75 ELDVLIRINHPHIVHVSNIFQRR-AKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQ 133
E+D+L +NH I+ IF+ + +I + GDLL+F+ GA+ E+ +R RQ
Sbjct: 60 EMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQ 119
Query: 134 IISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQ--RDRDVLSETYCGSL 191
+ S ++Y H ++I HRDLKCEN+L+ ++N+K++DFGF++ + R +LS+T+CGS
Sbjct: 120 LSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSA 179
Query: 192 SYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
+YAAPEVL+ +PY PK+ D+WS+GVILY M+ ++P++++ ++K+ ++ ++ R
Sbjct: 180 AYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKML--RIQKEHRVDFPR 237
Query: 252 VNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
L+ ECK+ + ++++P+ R + + +W+
Sbjct: 238 SKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL 272
>BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine
kinase 6 protein.
Length = 273
Score = 206 bits (503), Expect = 9e-53
Identities = 112/271 (41%), Positives = 162/271 (59%), Gaps = 11/271 (4%)
Query: 18 VLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELD 77
+L E G+ L + IGEGSY+KV AT + +A KV+D +AP D++ KFLPREL
Sbjct: 6 LLSELGYKLGRTIGEGSYSKVKVAT---SKKYKGTVAIKVVDRRRAPPDFVNKFLPRELS 62
Query: 78 VLIRINHPHIVHVSNIFQR-RAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIIS 136
+L + HPHIVHV + K +I + A DLL + +NG IP Q+R QI
Sbjct: 63 ILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAG 121
Query: 137 GLQYIHTMNIAHRDLKCENVLVTANYN-VKITDFGFARNVRQRDRDVLSETYCGSLSYAA 195
++Y+H ++ HRDLKCENVL++ + VK+TDFGF R LS TYCGS +YA+
Sbjct: 122 AVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPD--LSTTYCGSAAYAS 179
Query: 196 PEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQL 255
PEVL G+PY PK D+WS+GV+LY M+ +PF+++ + L +Q R + + +L
Sbjct: 180 PEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQ-KRGVLYPEGL--EL 236
Query: 256 STECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
S CK + +L++ P +RP+A V W+
Sbjct: 237 SERCKALIAELLQFSPSARPSAGQVARNCWL 267
>AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine
kinase 4 protein.
Length = 328
Score = 206 bits (503), Expect = 9e-53
Identities = 113/301 (37%), Positives = 179/301 (59%), Gaps = 23/301 (7%)
Query: 1 MGGGDKIDLS-TTQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIM-ACKVI 58
MG GD ++ + TT + +++ E G+ + K IG GSY VY+A + T+ +M A K+I
Sbjct: 1 MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFY----TKQKVMVAVKII 56
Query: 59 DTAKAPRDYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQ 118
KA DYL KFLPRE+ V+ + H ++++ + ++ +I L A+ GD+L+++ +
Sbjct: 57 SKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQR 116
Query: 119 NGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQR 178
GA E + W Q+ G+ Y+H+ +I HRDLK EN+L+ NVKI+DFGFA+ V
Sbjct: 117 YGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSN 176
Query: 179 D--------RDV-----LSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKA 225
R V LS+TYCGS +YA PE+L+G+PY P L+D WS+GVILYT++
Sbjct: 177 QPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAH 236
Query: 226 LPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTW 285
LPF++T++KKL ++ ++ F + +S ECK + Q++ K R T + +W
Sbjct: 237 LPFDDTNLKKLL-RETQKEVTFPAN--HTISQECKNLILQMLRQATK-RATILDIIKDSW 292
Query: 286 I 286
+
Sbjct: 293 V 293
>AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protein
kinase SSTK protein.
Length = 273
Score = 206 bits (503), Expect = 9e-53
Identities = 112/271 (41%), Positives = 162/271 (59%), Gaps = 11/271 (4%)
Query: 18 VLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELD 77
+L E G+ L + IGEGSY+KV AT + +A KV+D +AP D++ KFLPREL
Sbjct: 6 LLSELGYKLGRTIGEGSYSKVKVAT---SKKYKGTVAIKVVDRRRAPPDFVNKFLPRELS 62
Query: 78 VLIRINHPHIVHVSNIFQR-RAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIIS 136
+L + HPHIVHV + K +I + A DLL + +NG IP Q+R QI
Sbjct: 63 ILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAG 121
Query: 137 GLQYIHTMNIAHRDLKCENVLVTANYN-VKITDFGFARNVRQRDRDVLSETYCGSLSYAA 195
++Y+H ++ HRDLKCENVL++ + VK+TDFGF R LS TYCGS +YA+
Sbjct: 122 AVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPD--LSTTYCGSAAYAS 179
Query: 196 PEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQL 255
PEVL G+PY PK D+WS+GV+LY M+ +PF+++ + L +Q R + + +L
Sbjct: 180 PEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQ-KRGVLYPEGL--EL 236
Query: 256 STECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
S CK + +L++ P +RP+A V W+
Sbjct: 237 SERCKALIAELLQFSPSARPSAGQVARNCWL 267
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 202 bits (494), Expect = 1e-51
Identities = 101/269 (37%), Positives = 169/269 (62%), Gaps = 9/269 (3%)
Query: 19 LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDV 78
L G+ L K IGEG+Y+KV +A + + +A KVID P +++ +FLPREL +
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRK---VAIKVIDKMGGPEEFIQRFLPRELQI 61
Query: 79 LIRINHPHIVHVSNIFQRR-AKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISG 137
+ ++H +I+ V + + K + + AE GD+ D + G +PE++++ RQ++
Sbjct: 62 VRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEA 121
Query: 138 LQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
++Y H +AHRDLKCEN L+ +N+K+TDFGFA+ + + R+ LS+T+CGS +YAAPE
Sbjct: 122 IRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRE-LSQTFCGSTAYAAPE 179
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL+G+P+ K D+WS+GV+LY ML +LPF++T + K+ +Q + F T + +S
Sbjct: 180 VLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQ-QKGVSFPTHL--SISA 236
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+C++ + +L+EP+ RP+ V W+
Sbjct: 237 DCQDLLKRLLEPDMILRPSIEEVSWHPWL 265
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 202 bits (494), Expect = 1e-51
Identities = 101/269 (37%), Positives = 169/269 (62%), Gaps = 9/269 (3%)
Query: 19 LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDV 78
L G+ L K IGEG+Y+KV +A + + +A KVID P +++ +FLPREL +
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRK---VAIKVIDKMGGPEEFIQRFLPRELQI 61
Query: 79 LIRINHPHIVHVSNIFQRR-AKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISG 137
+ ++H +I+ V + + K + + AE GD+ D + G +PE++++ RQ++
Sbjct: 62 VRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEA 121
Query: 138 LQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
++Y H +AHRDLKCEN L+ +N+K+TDFGFA+ + + R+ LS+T+CGS +YAAPE
Sbjct: 122 IRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRE-LSQTFCGSTAYAAPE 179
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL+G+P+ K D+WS+GV+LY ML +LPF++T + K+ +Q + F T + +S
Sbjct: 180 VLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQ-QKGVSFPTHL--SISA 236
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+C++ + +L+EP+ RP+ V W+
Sbjct: 237 DCQDLLKRLLEPDMILRPSIEEVSWHPWL 265
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 202 bits (494), Expect = 1e-51
Identities = 101/269 (37%), Positives = 169/269 (62%), Gaps = 9/269 (3%)
Query: 19 LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDV 78
L G+ L K IGEG+Y+KV +A + + +A KVID P +++ +FLPREL +
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRK---VAIKVIDKMGGPEEFIQRFLPRELQI 61
Query: 79 LIRINHPHIVHVSNIFQRR-AKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISG 137
+ ++H +I+ V + + K + + AE GD+ D + G +PE++++ RQ++
Sbjct: 62 VRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEA 121
Query: 138 LQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
++Y H +AHRDLKCEN L+ +N+K+TDFGFA+ + + R+ LS+T+CGS +YAAPE
Sbjct: 122 IRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRE-LSQTFCGSTAYAAPE 179
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL+G+P+ K D+WS+GV+LY ML +LPF++T + K+ +Q + F T + +S
Sbjct: 180 VLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQ-QKGVSFPTHL--SISA 236
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+C++ + +L+EP+ RP+ V W+
Sbjct: 237 DCQDLLKRLLEPDMILRPSIEEVSWHPWL 265
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 202 bits (494), Expect = 1e-51
Identities = 101/269 (37%), Positives = 169/269 (62%), Gaps = 9/269 (3%)
Query: 19 LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDV 78
L G+ L K IGEG+Y+KV +A + + +A KVID P +++ +FLPREL +
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRK---VAIKVIDKMGGPEEFIQRFLPRELQI 61
Query: 79 LIRINHPHIVHVSNIFQRR-AKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISG 137
+ ++H +I+ V + + K + + AE GD+ D + G +PE++++ RQ++
Sbjct: 62 VRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEA 121
Query: 138 LQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
++Y H +AHRDLKCEN L+ +N+K+TDFGFA+ + + R+ LS+T+CGS +YAAPE
Sbjct: 122 IRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRE-LSQTFCGSTAYAAPE 179
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL+G+P+ K D+WS+GV+LY ML +LPF++T + K+ +Q + F T + +S
Sbjct: 180 VLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQ-QKGVSFPTHL--SISA 236
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+C++ + +L+EP+ RP+ V W+
Sbjct: 237 DCQDLLKRLLEPDMILRPSIEEVSWHPWL 265
>AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens
cDNA FLJ29008 fis, clone TST06032. ).
Length = 338
Score = 194 bits (474), Expect = 3e-49
Identities = 113/311 (36%), Positives = 179/311 (57%), Gaps = 33/311 (10%)
Query: 1 MGGGDKIDLS-TTQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIM-ACKVI 58
MG GD ++ + TT + +++ E G+ + K IG GSY VY+A + T+ +M A K+I
Sbjct: 1 MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFY----TKQKVMVAVKII 56
Query: 59 DTAKAPRDYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQ 118
KA DYL KFLPRE+ V+ + H ++++ + ++ +I L A+ GD+L+++ +
Sbjct: 57 SKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIRR 116
Query: 119 NGAIPENQSRLWMRQIISGLQYIHTMNIAHR----------DLKCENVLVTANYNVKITD 168
GA E + W Q+ G+ Y+H+ +I HR DLK EN+L+ NVKI+D
Sbjct: 117 YGACSEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSAAGRDLKLENLLLDKWENVKISD 176
Query: 169 FGFARNVRQRD--------RDV-----LSETYCGSLSYAAPEVLKGVPYMPKLADMWSIG 215
FGFA+ V R V LS+TYCGS +YA PE+L+G+PY P L+D WS+G
Sbjct: 177 FGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMG 236
Query: 216 VILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRP 275
VILYT++ LPF++T++KKL ++ ++ F + +S ECK + Q++ K R
Sbjct: 237 VILYTLVVAHLPFDDTNLKKLL-RETQKEVTFPAN--HTISQECKNLILQMLRQATK-RA 292
Query: 276 TASAVFNGTWI 286
T + +W+
Sbjct: 293 TILDIIKDSWV 303
>AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens
cDNA FLJ24002 fis, clone KAIA4350, highly similar to
Homo sapiens serine/threonine protein kinase SSTK
(SSTK). ).
Length = 406
Score = 191 bits (465), Expect = 4e-48
Identities = 106/256 (41%), Positives = 152/256 (59%), Gaps = 11/256 (4%)
Query: 18 VLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELD 77
+L E G+ L + IGEGSY+KV AT + +A KV+D +AP D++ KFLPREL
Sbjct: 6 LLSELGYKLGRTIGEGSYSKVKVAT---SKKYKGTVAIKVVDRRRAPPDFVNKFLPRELS 62
Query: 78 VLIRINHPHIVHVSNIFQR-RAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIIS 136
+L + HPHIVHV + K +I + A DLL + +NG IP Q+R QI
Sbjct: 63 ILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAG 121
Query: 137 GLQYIHTMNIAHRDLKCENVLVTANYN-VKITDFGFARNVRQRDRDVLSETYCGSLSYAA 195
++Y+H ++ HRDLKCENVL++ + VK+TDFGF R LS TYCGS +YA+
Sbjct: 122 AVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPD--LSTTYCGSAAYAS 179
Query: 196 PEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQL 255
PEVL G+PY PK D+WS+GV+LY M+ +PF+++ + L +Q R + + +L
Sbjct: 180 PEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQ-KRGVLYPEGL--EL 236
Query: 256 STECKEQVTQLMEPEP 271
S CK + + +P
Sbjct: 237 SERCKALIAEAAAVQP 252
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 172 bits (418), Expect = 2e-42
Identities = 89/263 (33%), Positives = 152/263 (57%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 22 LLKTIGKGNFAKVKLARHILTGKE---VAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHP 77
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 137
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A+ N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 138 IVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKKYD 194
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 250
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + W+ +
Sbjct: 251 FLILNPSKRGTLEQIMKDRWMNV 273
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 172 bits (418), Expect = 2e-42
Identities = 90/261 (34%), Positives = 150/261 (57%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 58 LLKTIGKGNFAKVKLARHILTGRE---VAIKIIDKTQLNPTSLQKLF-REVRIMKILNHP 113
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKR 173
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A+ N+KI DFGF+ + +T+CGS YAAPE+ +G Y
Sbjct: 174 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGK---LDTFCGSPPYAAPELFQGKKYD 230
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 231 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKR 286
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
+ P R T + WI
Sbjct: 287 FLVLNPIKRGTLEQIMKDRWI 307
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 172 bits (418), Expect = 2e-42
Identities = 89/263 (33%), Positives = 152/263 (57%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 22 LLKTIGKGNFAKVKLARHILTGKE---VAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHP 77
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 137
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A+ N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 138 IVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKKYD 194
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 250
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + W+ +
Sbjct: 251 FLILNPSKRGTLEQIMKDRWMNV 273
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 172 bits (418), Expect = 2e-42
Identities = 89/263 (33%), Positives = 152/263 (57%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 55 LLKTIGKGNFAKVKLARHILTGKE---VAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHP 110
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 111 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 170
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A+ N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 171 IVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKKYD 227
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 228 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 283
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + W+ +
Sbjct: 284 FLILNPSKRGTLEQIMKDRWMNV 306
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 172 bits (418), Expect = 2e-42
Identities = 90/261 (34%), Positives = 150/261 (57%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 58 LLKTIGKGNFAKVKLARHILTGRE---VAIKIIDKTQLNPTSLQKLF-REVRIMKILNHP 113
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKR 173
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A+ N+KI DFGF+ + +T+CGS YAAPE+ +G Y
Sbjct: 174 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGK---LDTFCGSPPYAAPELFQGKKYD 230
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 231 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKR 286
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
+ P R T + WI
Sbjct: 287 FLVLNPIKRGTLEQIMKDRWI 307
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 172 bits (418), Expect = 2e-42
Identities = 89/263 (33%), Positives = 152/263 (57%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 45 LLKTIGKGNFAKVKLARHILTGKE---VAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHP 100
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 101 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 160
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A+ N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 161 IVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKKYD 217
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 218 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 273
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + W+ +
Sbjct: 274 FLILNPSKRGTLEQIMKDRWMNV 296
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 172 bits (418), Expect = 2e-42
Identities = 89/263 (33%), Positives = 152/263 (57%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 22 LLKTIGKGNFAKVKLARHILTGKE---VAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHP 77
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 137
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A+ N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 138 IVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKKYD 194
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 250
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + W+ +
Sbjct: 251 FLILNPSKRGTLEQIMKDRWMNV 273
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 172 bits (418), Expect = 2e-42
Identities = 90/261 (34%), Positives = 150/261 (57%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 58 LLKTIGKGNFAKVKLARHILTGRE---VAIKIIDKTQLNPTSLQKLF-REVRIMKILNHP 113
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKR 173
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A+ N+KI DFGF+ + +T+CGS YAAPE+ +G Y
Sbjct: 174 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGK---LDTFCGSPPYAAPELFQGKKYD 230
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 231 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKR 286
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
+ P R T + WI
Sbjct: 287 FLVLNPIKRGTLEQIMKDRWI 307
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 172 bits (418), Expect = 2e-42
Identities = 89/263 (33%), Positives = 152/263 (57%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 55 LLKTIGKGNFAKVKLARHILTGKE---VAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHP 110
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 111 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF 170
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A+ N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 171 IVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKKYD 227
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 228 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 283
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + W+ +
Sbjct: 284 FLILNPSKRGTLEQIMKDRWMNV 306
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 171 bits (417), Expect = 2e-42
Identities = 88/263 (33%), Positives = 153/263 (58%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L+K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 62 LQKTIGKGNFAKVKLARHVLTGRE---VAVKIIDKTQLNPTSLQKLF-REVRIMKILNHP 117
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ + N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKKYD 234
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 290
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
L+ P R + + W+ +
Sbjct: 291 LLVLNPIKRGSLEQIMKDRWMNV 313
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 171 bits (417), Expect = 2e-42
Identities = 88/263 (33%), Positives = 153/263 (58%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L+K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 62 LQKTIGKGNFAKVKLARHVLTGRE---VAVKIIDKTQLNPTSLQKLF-REVRIMKILNHP 117
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ + N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKKYD 234
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 290
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
L+ P R + + W+ +
Sbjct: 291 LLVLNPIKRGSLEQIMKDRWMNV 313
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 171 bits (417), Expect = 2e-42
Identities = 90/263 (34%), Positives = 150/263 (57%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 61 LLRTIGKGNFAKVKLARHILTGRE---VAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHP 116
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S + Y H N
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A N+KI DFGF+ + +T+CGS YAAPE+ +G Y
Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQGKKYD 233
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R V +ST+C+ + +
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYR----VPFYMSTDCESILRR 289
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + WI +
Sbjct: 290 FLVLNPAKRCTLEQIMKDKWINI 312
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 171 bits (417), Expect = 2e-42
Identities = 90/263 (34%), Positives = 150/263 (57%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 61 LLRTIGKGNFAKVKLARHILTGRE---VAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHP 116
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S + Y H N
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A N+KI DFGF+ + +T+CGS YAAPE+ +G Y
Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQGKKYD 233
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R V +ST+C+ + +
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYR----VPFYMSTDCESILRR 289
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + WI +
Sbjct: 290 FLVLNPAKRCTLEQIMKDKWINI 312
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 171 bits (417), Expect = 2e-42
Identities = 88/263 (33%), Positives = 153/263 (58%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L+K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 62 LQKTIGKGNFAKVKLARHVLTGRE---VAVKIIDKTQLNPTSLQKLF-REVRIMKILNHP 117
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ + N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKKYD 234
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 290
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
L+ P R + + W+ +
Sbjct: 291 LLVLNPIKRGSLEQIMKDRWMNV 313
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 171 bits (417), Expect = 2e-42
Identities = 90/263 (34%), Positives = 150/263 (57%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 61 LLRTIGKGNFAKVKLARHILTGRE---VAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHP 116
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S + Y H N
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A N+KI DFGF+ + +T+CGS YAAPE+ +G Y
Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQGKKYD 233
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R V +ST+C+ + +
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYR----VPFYMSTDCESILRR 289
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + WI +
Sbjct: 290 FLVLNPAKRCTLEQIMKDKWINI 312
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 171 bits (417), Expect = 2e-42
Identities = 88/263 (33%), Positives = 153/263 (58%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L+K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 62 LQKTIGKGNFAKVKLARHVLTGRE---VAVKIIDKTQLNPTSLQKLF-REVRIMKILNHP 117
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ + N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKKYD 234
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 290
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
L+ P R + + W+ +
Sbjct: 291 LLVLNPIKRGSLEQIMKDRWMNV 313
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 171 bits (417), Expect = 2e-42
Identities = 90/263 (34%), Positives = 150/263 (57%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 62 LLRTIGKGNFAKVKLARHILTGRE---VAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHP 117
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S + Y H N
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 177
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A N+KI DFGF+ + +T+CGS YAAPE+ +G Y
Sbjct: 178 IVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQGKKYD 234
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R V +ST+C+ + +
Sbjct: 235 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYR----VPFYMSTDCESILRR 290
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + WI +
Sbjct: 291 FLVLNPAKRCTLEQIMKDKWINI 313
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 171 bits (416), Expect = 3e-42
Identities = 90/261 (34%), Positives = 150/261 (57%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 58 LLKTIGKGNFAKVKLARHILTGRE---VAIKIIDKTQLNPTSLQKLF-REVRIMKILNHP 113
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + + ++ + +A G + D+L +G + E ++R RQI+S +QY H
Sbjct: 114 NIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKR 173
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A+ N+KI DFGF+ + +T+CGS YAAPE+ +G Y
Sbjct: 174 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGK---LDTFCGSPPYAAPELFQGKKYD 230
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 231 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKR 286
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
+ P R T + WI
Sbjct: 287 FLVLNPIKRGTLEQIMKDRWI 307
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 171 bits (415), Expect = 4e-42
Identities = 90/261 (34%), Positives = 154/261 (59%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
+E+ +G+G++A V A H V +T+ +A K+ID + L K RE+ ++ +NHP
Sbjct: 29 IERTLGKGNFAVVKLARHRVTKTQ---VAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHP 84
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + + + + +I FA+NG++ D+LT NG + EN++R QI+S ++Y H +
Sbjct: 85 HIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHH 144
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N ++K+ DFGF + + LS T+CGS YAAPEV +G Y
Sbjct: 145 IVHRDLKTENLLLDGNMDIKLADFGFGN--FYKSGEPLS-TWCGSPPYAAPEVFEGKEYE 201
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GV+LY ++ +LPF+ ++ L +Q + + RFR +S +C+ + +
Sbjct: 202 GPQLDIWSLGVVLYVLVCGSLPFDGPNLPTL--RQRVLEGRFRIPFF--MSQDCESLIRR 257
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
++ +P R T + + W+
Sbjct: 258 MLVVDPARRITIAQIRQHRWM 278
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 171 bits (415), Expect = 4e-42
Identities = 90/261 (34%), Positives = 154/261 (59%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
+E+ +G+G++A V A H V +T+ +A K+ID + L K RE+ ++ +NHP
Sbjct: 10 IERTLGKGNFAVVKLARHRVTKTQ---VAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHP 65
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + + + + +I FA+NG++ D+LT NG + EN++R QI+S ++Y H +
Sbjct: 66 HIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHH 125
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N ++K+ DFGF + + LS T+CGS YAAPEV +G Y
Sbjct: 126 IVHRDLKTENLLLDGNMDIKLADFGFGN--FYKSGEPLS-TWCGSPPYAAPEVFEGKEYE 182
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GV+LY ++ +LPF+ ++ L +Q + + RFR +S +C+ + +
Sbjct: 183 GPQLDIWSLGVVLYVLVCGSLPFDGPNLPTL--RQRVLEGRFRIPFF--MSQDCESLIRR 238
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
++ +P R T + + W+
Sbjct: 239 MLVVDPARRITIAQIRQHRWM 259
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 171 bits (415), Expect = 4e-42
Identities = 90/261 (34%), Positives = 149/261 (57%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 58 LLKTIGKGNFAKVKLARHILTGRE---VAIKIIDKTQLNPTSLQKLF-REVRIMKILNHP 113
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G + D+L +G + E ++R RQI+S +QY H
Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKR 173
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A+ N+KI DFGF+ + +T+CGS YAAPE+ +G Y
Sbjct: 174 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGK---LDTFCGSPPYAAPELFQGKKYD 230
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 231 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKR 286
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
+ P R T + WI
Sbjct: 287 FLVLNPIKRGTLEQIMKDRWI 307
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 171 bits (415), Expect = 4e-42
Identities = 90/261 (34%), Positives = 154/261 (59%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
+E+ +G+G++A V A H V +T+ +A K+ID + L K RE+ ++ +NHP
Sbjct: 29 IERTLGKGNFAVVKLARHRVTKTQ---VAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHP 84
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + + + + +I FA+NG++ D+LT NG + EN++R QI+S ++Y H +
Sbjct: 85 HIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHH 144
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N ++K+ DFGF + + LS T+CGS YAAPEV +G Y
Sbjct: 145 IVHRDLKTENLLLDGNMDIKLADFGFGN--FYKSGEPLS-TWCGSPPYAAPEVFEGKEYE 201
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GV+LY ++ +LPF+ ++ L +Q + + RFR +S +C+ + +
Sbjct: 202 GPQLDIWSLGVVLYVLVCGSLPFDGPNLPTL--RQRVLEGRFRIPFF--MSQDCESLIRR 257
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
++ +P R T + + W+
Sbjct: 258 MLVVDPARRITIAQIRQHRWM 278
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 169 bits (412), Expect = 1e-41
Identities = 90/263 (34%), Positives = 149/263 (56%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + IG+G+ AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 61 LLRTIGKGNSAKVKLARHILTGRE---VAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHP 116
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S + Y H N
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A N+KI DFGF+ + +T+CGS YAAPE+ +G Y
Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQGKKYD 233
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R V +ST+C+ + +
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYR----VPFYMSTDCESILRR 289
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + WI +
Sbjct: 290 FLVLNPAKRCTLEQIMKDKWINI 312
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 169 bits (412), Expect = 1e-41
Identities = 90/263 (34%), Positives = 149/263 (56%), Gaps = 11/263 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + IG+G+ AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 61 LLRTIGKGNSAKVKLARHILTGRE---VAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHP 116
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + + + ++ + +A G++ D+L +G + E ++R RQI+S + Y H N
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKN 176
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ A N+KI DFGF+ + +T+CGS YAAPE+ +G Y
Sbjct: 177 IVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQGKKYD 233
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R V +ST+C+ + +
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYR----VPFYMSTDCESILRR 289
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
+ P R T + WI +
Sbjct: 290 FLVLNPAKRCTLEQIMKDKWINI 312
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 168 bits (408), Expect = 3e-41
Identities = 83/261 (31%), Positives = 150/261 (57%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
+++ IG+G++A V +ATH+V + + +A K+ID + + L K RE+ ++ + HP
Sbjct: 10 IDRTIGKGNFAVVKRATHLVTKAK---VAIKIIDKTQLDEENLKKIF-REVQIMKMLCHP 65
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + + + ++ +A G++ D L +G + E ++R +QI++ + + H N
Sbjct: 66 HIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRN 125
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ AN N+KI DFGF+ L +T+CGS YAAPE+ +G Y
Sbjct: 126 IVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ---LLKTWCGSPPYAAPELFEGKEYD 182
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GV+LY ++ ALPF+ ++++ L + + K+R + +STEC+ +
Sbjct: 183 GPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFR----IPFFMSTECEHLIRH 238
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
++ +P R + + W+
Sbjct: 239 MLVLDPNKRLSMEQICKHKWM 259
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 168 bits (408), Expect = 3e-41
Identities = 83/261 (31%), Positives = 150/261 (57%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
+++ IG+G++A V +ATH+V + + +A K+ID + + L K RE+ ++ + HP
Sbjct: 118 IDRTIGKGNFAVVKRATHLVTKAK---VAIKIIDKTQLDEENLKKIF-REVQIMKMLCHP 173
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + + + ++ +A G++ D L +G + E ++R +QI++ + + H N
Sbjct: 174 HIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRN 233
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ AN N+KI DFGF+ L +T+CGS YAAPE+ +G Y
Sbjct: 234 IVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ---LLKTWCGSPPYAAPELFEGKEYD 290
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GV+LY ++ ALPF+ ++++ L + + K+R + +STEC+ +
Sbjct: 291 GPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFR----IPFFMSTECEHLIRH 346
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
++ +P R + + W+
Sbjct: 347 MLVLDPNKRLSMEQICKHKWM 367
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 167 bits (407), Expect = 4e-41
Identities = 97/312 (31%), Positives = 167/312 (53%), Gaps = 16/312 (5%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
E+ + +++G+GS+ V +AT ET+ +I K ++ KA + K L RE+++L
Sbjct: 113 EEIYTFGRILGKGSFGIVIEATDKETETKWAI---KKVNKEKAGSSAV-KLLEREVNILK 168
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+ H HI+H+ +F+ K ++ + E+G+L + L + G EN++R ++ + S + Y
Sbjct: 169 SVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAY 228
Query: 141 IHTMNIAHRDLKCENVLVTA---------NYNVKITDFGFARNVRQRDRDVLSETYCGSL 191
+H +I HRDLK EN++V + N N+K+TDFG A + R +L T CG+
Sbjct: 229 LHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQAT-CGTP 287
Query: 192 SYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
Y APEV+ Y + D+WSIGV++Y +L PF +S +KL+E + F V
Sbjct: 288 IYMAPEVISAHDYSQQ-CDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAV 346
Query: 252 VNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI-GMDSRLAKLTFLEESLLKQAHEES 310
N +S K + QLM+ +P R TA + + W+ G + T + E + + +
Sbjct: 347 WNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPE 406
Query: 311 QKRDNSTEEDSE 322
+N+TEE ++
Sbjct: 407 SVEENTTEEKNK 418
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 167 bits (407), Expect = 4e-41
Identities = 97/312 (31%), Positives = 167/312 (53%), Gaps = 16/312 (5%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
E+ + +++G+GS+ V +AT ET+ +I K ++ KA + K L RE+++L
Sbjct: 113 EEIYTFGRILGKGSFGIVIEATDKETETKWAI---KKVNKEKAGSSAV-KLLEREVNILK 168
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+ H HI+H+ +F+ K ++ + E+G+L + L + G EN++R ++ + S + Y
Sbjct: 169 SVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAY 228
Query: 141 IHTMNIAHRDLKCENVLVTA---------NYNVKITDFGFARNVRQRDRDVLSETYCGSL 191
+H +I HRDLK EN++V + N N+K+TDFG A + R +L T CG+
Sbjct: 229 LHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQAT-CGTP 287
Query: 192 SYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
Y APEV+ Y + D+WSIGV++Y +L PF +S +KL+E + F V
Sbjct: 288 IYMAPEVISAHDYSQQ-CDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAV 346
Query: 252 VNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI-GMDSRLAKLTFLEESLLKQAHEES 310
N +S K + QLM+ +P R TA + + W+ G + T + E + + +
Sbjct: 347 WNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPE 406
Query: 311 QKRDNSTEEDSE 322
+N+TEE ++
Sbjct: 407 SVEENTTEEKNK 418
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 167 bits (407), Expect = 4e-41
Identities = 97/312 (31%), Positives = 167/312 (53%), Gaps = 16/312 (5%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
E+ + +++G+GS+ V +AT ET+ +I K ++ KA + K L RE+++L
Sbjct: 113 EEIYTFGRILGKGSFGIVIEATDKETETKWAI---KKVNKEKAGSSAV-KLLEREVNILK 168
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+ H HI+H+ +F+ K ++ + E+G+L + L + G EN++R ++ + S + Y
Sbjct: 169 SVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAY 228
Query: 141 IHTMNIAHRDLKCENVLVTA---------NYNVKITDFGFARNVRQRDRDVLSETYCGSL 191
+H +I HRDLK EN++V + N N+K+TDFG A + R +L T CG+
Sbjct: 229 LHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQAT-CGTP 287
Query: 192 SYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
Y APEV+ Y + D+WSIGV++Y +L PF +S +KL+E + F V
Sbjct: 288 IYMAPEVISAHDYSQQ-CDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAV 346
Query: 252 VNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI-GMDSRLAKLTFLEESLLKQAHEES 310
N +S K + QLM+ +P R TA + + W+ G + T + E + + +
Sbjct: 347 WNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPE 406
Query: 311 QKRDNSTEEDSE 322
+N+TEE ++
Sbjct: 407 SVEENTTEEKNK 418
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 165 bits (400), Expect = 3e-40
Identities = 90/264 (34%), Positives = 154/264 (58%), Gaps = 14/264 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
+E+ +G+G++A V A H V +T+ +A K+ID + L K RE+ ++ +NHP
Sbjct: 29 IERTLGKGNFAVVKLARHRVTKTQ---VAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHP 84
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + + + + +I FA+NG++ D+LT NG + EN++R QI+S ++Y H +
Sbjct: 85 HIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHH 144
Query: 146 IAHRDLKCENVLVTANYNVKIT---DFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
I HRDLK EN+L+ N ++K+ DFGF + + LS T+CGS YAAPEV +G
Sbjct: 145 IVHRDLKTENLLLDGNMDIKLAGTEDFGFGN--FYKSGEPLS-TWCGSPPYAAPEVFEGK 201
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262
Y D+WS+GV+LY ++ +LPF+ ++ L +Q + + RFR +S +C+
Sbjct: 202 EYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTL--RQRVLEGRFRIPFF--MSQDCESL 257
Query: 263 VTQLMEPEPKSRPTASAVFNGTWI 286
+ +++ +P R T + + W+
Sbjct: 258 IRRMLVVDPARRITIAQIRQHRWM 281
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 163 bits (395), Expect = 1e-39
Identities = 90/260 (34%), Positives = 145/260 (55%), Gaps = 10/260 (3%)
Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRD-YLTKFLPRELDVLIRINHPHIV 88
+GEGS+AKV + H++ + +A KVID +A +D Y+TK L RE + I HP+I
Sbjct: 68 LGEGSFAKVREGLHVLTGEK---VAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNIT 124
Query: 89 HVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAH 148
+ +I + Y++ + G+L+ + + + E+++R ++RQ+IS ++++H + H
Sbjct: 125 QLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVH 184
Query: 149 RDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKL 208
RDLK EN+L+ + N+K+ DFG + T CGS +YAAPE+L Y PK+
Sbjct: 185 RDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKI 244
Query: 209 ADMWSIGVILYTMLNKALPF--NETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQL 266
D+WSIGV +Y ML LPF S++ LY+K V ++ + QLST + L
Sbjct: 245 -DVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKE---MNPLPTQLSTGAISFLRSL 300
Query: 267 MEPEPKSRPTASAVFNGTWI 286
+EP+P RP W+
Sbjct: 301 LEPDPVKRPNIQQALANRWL 320
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 163 bits (395), Expect = 1e-39
Identities = 81/261 (31%), Positives = 146/261 (55%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L++ +G+G+Y KV +AT + ++A K I K + + RE++++ +NHP
Sbjct: 94 LQETLGKGTYGKVKRAT---ERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHP 150
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + +F+ + K I + +A G+L D++++ + E ++R + RQI+S + Y H
Sbjct: 151 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNG 210
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
+ HRDLK EN+L+ N N+KI DFG + N+ Q+D+ +T+CGS YA+PE++ G PY
Sbjct: 211 VVHRDLKLENILLDDNCNIKIADFGLS-NLYQKDK--FLQTFCGSPLYASPEIVNGRPYR 267
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D W++GV+LYT++ +PF+ K L + ++R T ++ + +
Sbjct: 268 GPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQ-----PSDARGLIRW 322
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
++ P R T + N W+
Sbjct: 323 MLMVNPDRRATIEDIANHWWV 343
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 161 bits (391), Expect = 3e-39
Identities = 84/261 (32%), Positives = 150/261 (57%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
+E +G+G++A V H + +T +A K+ID ++ L K RE+ ++ ++HP
Sbjct: 22 IEGTLGKGNFAVVKLGRHRITKTE---VAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHP 77
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + + + ++ ++ +A+NG++ D+L +G + E+++R QI+S + Y H
Sbjct: 78 HIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRK 137
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N N+KI DFGF + + L T+CGS YAAPEV +G Y
Sbjct: 138 IVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGE---LLATWCGSPPYAAPEVFEGQQYE 194
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GV+LY ++ ALPF+ ++ L +Q + + RFR + +S +C+ + +
Sbjct: 195 GPQLDIWSMGVVLYVLVCGALPFDGPTLPIL--RQRVLEGRFR--IPYFMSEDCEHLIRR 250
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
++ +P R T + + W+
Sbjct: 251 MLVLDPSKRLTIAQIKEHKWM 271
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 161 bits (391), Expect = 3e-39
Identities = 84/261 (32%), Positives = 150/261 (57%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
+E +G+G++A V H + +T +A K+ID ++ L K RE+ ++ ++HP
Sbjct: 22 IEGTLGKGNFAVVKLGRHRITKTE---VAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHP 77
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + + + ++ ++ +A+NG++ D+L +G + E+++R QI+S + Y H
Sbjct: 78 HIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRK 137
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N N+KI DFGF + + L T+CGS YAAPEV +G Y
Sbjct: 138 IVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGE---LLATWCGSPPYAAPEVFEGQQYE 194
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GV+LY ++ ALPF+ ++ L +Q + + RFR + +S +C+ + +
Sbjct: 195 GPQLDIWSMGVVLYVLVCGALPFDGPTLPIL--RQRVLEGRFR--IPYFMSEDCEHLIRR 250
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
++ +P R T + + W+
Sbjct: 251 MLVLDPSKRLTIAQIKEHKWM 271
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 161 bits (391), Expect = 3e-39
Identities = 86/260 (33%), Positives = 147/260 (56%), Gaps = 11/260 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK +G+G V H + + +A K+++ K L K + RE+ +L I HP
Sbjct: 36 LEKTLGKGQTGLVKLGVHCITGQK---VAIKIVNREKLSESVLMK-VEREIAILKLIEHP 91
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
H++ + ++++ + ++ L G+L D+L + G + ++R + RQI+S L + H+ +
Sbjct: 92 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYS 151
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV+KG Y
Sbjct: 152 ICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIKGEKYD 208
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
+ ADMWS GVIL+ +L ALPF++ ++++L EK +++ F + + + +C+ +
Sbjct: 209 GRRADMWSCGVILFALLVGALPFDDDNLRQLLEK--VKRGVFH--MPHFIPPDCQSLLRG 264
Query: 266 LMEPEPKSRPTASAVFNGTW 285
++E EP+ R + + W
Sbjct: 265 MIEVEPEKRLSLEQIQKHPW 284
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 161 bits (391), Expect = 3e-39
Identities = 86/260 (33%), Positives = 147/260 (56%), Gaps = 11/260 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK +G+G V H + + +A K+++ K L K + RE+ +L I HP
Sbjct: 36 LEKTLGKGQTGLVKLGVHCITGQK---VAIKIVNREKLSESVLMK-VEREIAILKLIEHP 91
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
H++ + ++++ + ++ L G+L D+L + G + ++R + RQI+S L + H+ +
Sbjct: 92 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYS 151
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV+KG Y
Sbjct: 152 ICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIKGEKYD 208
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
+ ADMWS GVIL+ +L ALPF++ ++++L EK +++ F + + + +C+ +
Sbjct: 209 GRRADMWSCGVILFALLVGALPFDDDNLRQLLEK--VKRGVFH--MPHFIPPDCQSLLRG 264
Query: 266 LMEPEPKSRPTASAVFNGTW 285
++E EP+ R + + W
Sbjct: 265 MIEVEPEKRLSLEQIQKHPW 284
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 161 bits (391), Expect = 3e-39
Identities = 86/260 (33%), Positives = 147/260 (56%), Gaps = 11/260 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK +G+G V H + + +A K+++ K L K + RE+ +L I HP
Sbjct: 36 LEKTLGKGQTGLVKLGVHCITGQK---VAIKIVNREKLSESVLMK-VEREIAILKLIEHP 91
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
H++ + ++++ + ++ L G+L D+L + G + ++R + RQI+S L + H+ +
Sbjct: 92 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYS 151
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV+KG Y
Sbjct: 152 ICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIKGEKYD 208
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
+ ADMWS GVIL+ +L ALPF++ ++++L EK +++ F + + + +C+ +
Sbjct: 209 GRRADMWSCGVILFALLVGALPFDDDNLRQLLEK--VKRGVFH--MPHFIPPDCQSLLRG 264
Query: 266 LMEPEPKSRPTASAVFNGTW 285
++E EP+ R + + W
Sbjct: 265 MIEVEPEKRLSLEQIQKHPW 284
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 161 bits (391), Expect = 3e-39
Identities = 86/260 (33%), Positives = 147/260 (56%), Gaps = 11/260 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK +G+G V H + + +A K+++ K L K + RE+ +L I HP
Sbjct: 52 LEKTLGKGQTGLVKLGVHCITGQK---VAIKIVNREKLSESVLMK-VEREIAILKLIEHP 107
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
H++ + ++++ + ++ L G+L D+L + G + ++R + RQI+S L + H+ +
Sbjct: 108 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYS 167
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV+KG Y
Sbjct: 168 ICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIKGEKYD 224
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
+ ADMWS GVIL+ +L ALPF++ ++++L EK +++ F + + + +C+ +
Sbjct: 225 GRRADMWSCGVILFALLVGALPFDDDNLRQLLEK--VKRGVFH--MPHFIPPDCQSLLRG 280
Query: 266 LMEPEPKSRPTASAVFNGTW 285
++E EP+ R + + W
Sbjct: 281 MIEVEPEKRLSLEQIQKHPW 300
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 161 bits (391), Expect = 3e-39
Identities = 84/261 (32%), Positives = 150/261 (57%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
+E +G+G++A V H + +T +A K+ID ++ L K RE+ ++ ++HP
Sbjct: 20 IEGTLGKGNFAVVKLGRHRITKTE---VAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHP 75
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + + + ++ ++ +A+NG++ D+L +G + E+++R QI+S + Y H
Sbjct: 76 HIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRK 135
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N N+KI DFGF + + L T+CGS YAAPEV +G Y
Sbjct: 136 IVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGE---LLATWCGSPPYAAPEVFEGQQYE 192
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GV+LY ++ ALPF+ ++ L +Q + + RFR + +S +C+ + +
Sbjct: 193 GPQLDIWSMGVVLYVLVCGALPFDGPTLPIL--RQRVLEGRFR--IPYFMSEDCEHLIRR 248
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
++ +P R T + + W+
Sbjct: 249 MLVLDPSKRLTIAQIKEHKWM 269
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 161 bits (391), Expect = 3e-39
Identities = 84/261 (32%), Positives = 150/261 (57%), Gaps = 11/261 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
+E +G+G++A V H + +T +A K+ID ++ L K RE+ ++ ++HP
Sbjct: 46 IEGTLGKGNFAVVKLGRHRITKTE---VAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHP 101
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + + + ++ ++ +A+NG++ D+L +G + E+++R QI+S + Y H
Sbjct: 102 HIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRK 161
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N N+KI DFGF + + L T+CGS YAAPEV +G Y
Sbjct: 162 IVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGE---LLATWCGSPPYAAPEVFEGQQYE 218
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GV+LY ++ ALPF+ ++ L +Q + + RFR + +S +C+ + +
Sbjct: 219 GPQLDIWSMGVVLYVLVCGALPFDGPTLPIL--RQRVLEGRFR--IPYFMSEDCEHLIRR 274
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
++ +P R T + + W+
Sbjct: 275 MLVLDPSKRLTIAQIKEHKWM 295
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 158 bits (384), Expect = 2e-38
Identities = 89/271 (32%), Positives = 152/271 (56%), Gaps = 16/271 (5%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR---ELDV 78
K + L + IG G +AKV A H++ ++A K++D ++ L LPR E++
Sbjct: 14 KYYELHETIGTGGFAKVKLACHILTG---EMVAIKIMD-----KNTLGSDLPRIKTEIEA 65
Query: 79 LIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138
L + H HI + ++ + K F+ L + G+L D++ + E ++R+ RQI+S +
Sbjct: 66 LKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAV 125
Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEV 198
Y+H+ AHRDLK EN+L + +K+ DFG + ++D +T CGSL+YAAPE+
Sbjct: 126 AYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPK-GNKDYHLQTCCGSLAYAAPEL 184
Query: 199 LKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258
++G Y+ AD+WS+G++LY ++ LPF++ +V LY K++MR + V LS
Sbjct: 185 IQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALY-KKIMRG---KYDVPKWLSPS 240
Query: 259 CKEQVTQLMEPEPKSRPTASAVFNGTWIGMD 289
+ Q+++ +PK R + + N WI D
Sbjct: 241 SILLLQQMLQVDPKKRISMKNLLNHPWIMQD 271
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 158 bits (384), Expect = 2e-38
Identities = 89/271 (32%), Positives = 152/271 (56%), Gaps = 16/271 (5%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR---ELDV 78
K + L + IG G +AKV A H++ ++A K++D ++ L LPR E++
Sbjct: 9 KYYELHETIGTGGFAKVKLACHILTG---EMVAIKIMD-----KNTLGSDLPRIKTEIEA 60
Query: 79 LIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138
L + H HI + ++ + K F+ L + G+L D++ + E ++R+ RQI+S +
Sbjct: 61 LKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAV 120
Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEV 198
Y+H+ AHRDLK EN+L + +K+ DFG + ++D +T CGSL+YAAPE+
Sbjct: 121 AYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPK-GNKDYHLQTCCGSLAYAAPEL 179
Query: 199 LKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258
++G Y+ AD+WS+G++LY ++ LPF++ +V LY K++MR + V LS
Sbjct: 180 IQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALY-KKIMRG---KYDVPKWLSPS 235
Query: 259 CKEQVTQLMEPEPKSRPTASAVFNGTWIGMD 289
+ Q+++ +PK R + + N WI D
Sbjct: 236 SILLLQQMLQVDPKKRISMKNLLNHPWIMQD 266
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 158 bits (384), Expect = 2e-38
Identities = 89/271 (32%), Positives = 152/271 (56%), Gaps = 16/271 (5%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR---ELDV 78
K + L + IG G +AKV A H++ ++A K++D ++ L LPR E++
Sbjct: 9 KYYELHETIGTGGFAKVKLACHILTG---EMVAIKIMD-----KNTLGSDLPRIKTEIEA 60
Query: 79 LIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138
L + H HI + ++ + K F+ L + G+L D++ + E ++R+ RQI+S +
Sbjct: 61 LKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAV 120
Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEV 198
Y+H+ AHRDLK EN+L + +K+ DFG + ++D +T CGSL+YAAPE+
Sbjct: 121 AYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPK-GNKDYHLQTCCGSLAYAAPEL 179
Query: 199 LKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258
++G Y+ AD+WS+G++LY ++ LPF++ +V LY K++MR + V LS
Sbjct: 180 IQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALY-KKIMRG---KYDVPKWLSPS 235
Query: 259 CKEQVTQLMEPEPKSRPTASAVFNGTWIGMD 289
+ Q+++ +PK R + + N WI D
Sbjct: 236 SILLLQQMLQVDPKKRISMKNLLNHPWIMQD 266
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 158 bits (384), Expect = 2e-38
Identities = 89/271 (32%), Positives = 152/271 (56%), Gaps = 16/271 (5%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR---ELDV 78
K + L + IG G +AKV A H++ ++A K++D ++ L LPR E++
Sbjct: 9 KYYELHETIGTGGFAKVKLACHILTG---EMVAIKIMD-----KNTLGSDLPRIKTEIEA 60
Query: 79 LIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138
L + H HI + ++ + K F+ L + G+L D++ + E ++R+ RQI+S +
Sbjct: 61 LKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAV 120
Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEV 198
Y+H+ AHRDLK EN+L + +K+ DFG + ++D +T CGSL+YAAPE+
Sbjct: 121 AYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPK-GNKDYHLQTCCGSLAYAAPEL 179
Query: 199 LKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258
++G Y+ AD+WS+G++LY ++ LPF++ +V LY K++MR + V LS
Sbjct: 180 IQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALY-KKIMRG---KYDVPKWLSPS 235
Query: 259 CKEQVTQLMEPEPKSRPTASAVFNGTWIGMD 289
+ Q+++ +PK R + + N WI D
Sbjct: 236 SILLLQQMLQVDPKKRISMKNLLNHPWIMQD 266
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 158 bits (384), Expect = 2e-38
Identities = 89/271 (32%), Positives = 152/271 (56%), Gaps = 16/271 (5%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPR---ELDV 78
K + L + IG G +AKV A H++ ++A K++D ++ L LPR E++
Sbjct: 9 KYYELHETIGTGGFAKVKLACHILTG---EMVAIKIMD-----KNTLGSDLPRIKTEIEA 60
Query: 79 LIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138
L + H HI + ++ + K F+ L + G+L D++ + E ++R+ RQI+S +
Sbjct: 61 LKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAV 120
Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEV 198
Y+H+ AHRDLK EN+L + +K+ DFG + ++D +T CGSL+YAAPE+
Sbjct: 121 AYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPK-GNKDYHLQTCCGSLAYAAPEL 179
Query: 199 LKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258
++G Y+ AD+WS+G++LY ++ LPF++ +V LY K++MR + V LS
Sbjct: 180 IQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALY-KKIMRG---KYDVPKWLSPS 235
Query: 259 CKEQVTQLMEPEPKSRPTASAVFNGTWIGMD 289
+ Q+++ +PK R + + N WI D
Sbjct: 236 SILLLQQMLQVDPKKRISMKNLLNHPWIMQD 266
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 155 bits (377), Expect = 2e-37
Identities = 75/214 (35%), Positives = 125/214 (58%), Gaps = 8/214 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHI 87
+ +G+G+Y KV KA E+ ++A K I K + + RE++++ +NHPHI
Sbjct: 57 ETLGKGTYGKVKKAR----ESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHI 112
Query: 88 VHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIA 147
+ + +F+ +K I + +A GDL D++++ + E ++R + RQI+S + Y H +
Sbjct: 113 IAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVV 172
Query: 148 HRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPK 207
HRDLK EN+L+ AN N+KI DFG + Q +T+CGS YA+PE++ G PY
Sbjct: 173 HRDLKLENILLDANGNIKIADFGLSNLYHQ---GKFLQTFCGSPLYASPEIVNGKPYTGP 229
Query: 208 LADMWSIGVILYTMLNKALPFNETSVKKLYEKQV 241
D WS+GV+LY +++ +PF+ K+ KQ+
Sbjct: 230 EVDSWSLGVLLYILVHGTMPFDGHD-HKILVKQI 262
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 155 bits (377), Expect = 2e-37
Identities = 75/214 (35%), Positives = 125/214 (58%), Gaps = 8/214 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHI 87
+ +G+G+Y KV KA E+ ++A K I K + + RE++++ +NHPHI
Sbjct: 57 ETLGKGTYGKVKKAR----ESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHI 112
Query: 88 VHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIA 147
+ + +F+ +K I + +A GDL D++++ + E ++R + RQI+S + Y H +
Sbjct: 113 IAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVV 172
Query: 148 HRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPK 207
HRDLK EN+L+ AN N+KI DFG + Q +T+CGS YA+PE++ G PY
Sbjct: 173 HRDLKLENILLDANGNIKIADFGLSNLYHQ---GKFLQTFCGSPLYASPEIVNGKPYTGP 229
Query: 208 LADMWSIGVILYTMLNKALPFNETSVKKLYEKQV 241
D WS+GV+LY +++ +PF+ K+ KQ+
Sbjct: 230 EVDSWSLGVLLYILVHGTMPFDGHD-HKILVKQI 262
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 153 bits (372), Expect = 7e-37
Identities = 85/260 (32%), Positives = 145/260 (55%), Gaps = 11/260 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK +G+G V H V + +A K+++ K L K + RE+ +L I HP
Sbjct: 21 LEKTLGKGQTGLVKLGVHCVTCQK---VAIKIVNREKLSESVLMK-VEREIAILKLIEHP 76
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
H++ + ++++ + ++ L G+L D+L + G + ++R + RQIIS L + H+ +
Sbjct: 77 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHS 136
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV++G Y
Sbjct: 137 ICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIRGEKYD 193
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
+ AD+WS GVIL+ +L ALPF++ ++++L EK +++ F + + + +C+ +
Sbjct: 194 GRKADVWSCGVILFALLVGALPFDDDNLRQLLEK--VKRGVFH--MPHFIPPDCQSLLRG 249
Query: 266 LMEPEPKSRPTASAVFNGTW 285
++E + R T + W
Sbjct: 250 MIEVDAARRLTLEHIQKHIW 269
>BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein.
Length = 252
Score = 153 bits (370), Expect = 1e-36
Identities = 79/218 (36%), Positives = 129/218 (59%), Gaps = 17/218 (7%)
Query: 82 INHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
+ H ++++ + ++ +I L A+ GD+L+++ + GA E + W Q+ G+ Y+
Sbjct: 4 LRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYL 63
Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRD--------RDV-----LSETYC 188
H+ +I HRDLK EN+L+ NVKI+DFGFA+ V R V LS+TYC
Sbjct: 64 HSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYC 123
Query: 189 GSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFR 248
GS +YA PE+L+G+PY P L+D WS+GVILYT++ LPF++T++KKL ++ ++ F
Sbjct: 124 GSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLL-RETQKEVTFP 182
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+ +S ECK + Q++ K R T + +W+
Sbjct: 183 AN--HTISQECKNLILQMLRQATK-RATILDIIKDSWV 217
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 153 bits (370), Expect = 1e-36
Identities = 79/214 (36%), Positives = 126/214 (58%), Gaps = 7/214 (3%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK +G+G V H V + +A K+++ K L K + RE+ +L I HP
Sbjct: 21 LEKTLGKGQTGLVKLGVHCVTCQK---VAIKIVNREKLSESVLMK-VEREIAILKLIEHP 76
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
H++ + ++++ + ++ L G+L D+L + G + ++R + RQIIS L + H+ +
Sbjct: 77 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHS 136
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV++G Y
Sbjct: 137 ICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIRGEKYD 193
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEK 239
+ AD+WS GVIL+ +L ALPF++ ++++L EK
Sbjct: 194 GRKADVWSCGVILFALLVGALPFDDDNLRQLLEK 227
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 153 bits (370), Expect = 1e-36
Identities = 79/214 (36%), Positives = 126/214 (58%), Gaps = 7/214 (3%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK +G+G V H V + +A K+++ K L K + RE+ +L I HP
Sbjct: 21 LEKTLGKGQTGLVKLGVHCVTCQK---VAIKIVNREKLSESVLMK-VEREIAILKLIEHP 76
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
H++ + ++++ + ++ L G+L D+L + G + ++R + RQIIS L + H+ +
Sbjct: 77 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHS 136
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV++G Y
Sbjct: 137 ICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIRGEKYD 193
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEK 239
+ AD+WS GVIL+ +L ALPF++ ++++L EK
Sbjct: 194 GRKADVWSCGVILFALLVGALPFDDDNLRQLLEK 227
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 153 bits (370), Expect = 1e-36
Identities = 79/214 (36%), Positives = 126/214 (58%), Gaps = 7/214 (3%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK +G+G V H V + +A K+++ K L K + RE+ +L I HP
Sbjct: 21 LEKTLGKGQTGLVKLGVHCVTCQK---VAIKIVNREKLSESVLMK-VEREIAILKLIEHP 76
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
H++ + ++++ + ++ L G+L D+L + G + ++R + RQIIS L + H+ +
Sbjct: 77 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHS 136
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV++G Y
Sbjct: 137 ICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIRGEKYD 193
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEK 239
+ AD+WS GVIL+ +L ALPF++ ++++L EK
Sbjct: 194 GRKADVWSCGVILFALLVGALPFDDDNLRQLLEK 227
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 153 bits (370), Expect = 1e-36
Identities = 79/214 (36%), Positives = 126/214 (58%), Gaps = 7/214 (3%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK +G+G V H V + +A K+++ K L K + RE+ +L I HP
Sbjct: 21 LEKTLGKGQTGLVKLGVHCVTCQK---VAIKIVNREKLSESVLMK-VEREIAILKLIEHP 76
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
H++ + ++++ + ++ L G+L D+L + G + ++R + RQIIS L + H+ +
Sbjct: 77 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHS 136
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV++G Y
Sbjct: 137 ICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIRGEKYD 193
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEK 239
+ AD+WS GVIL+ +L ALPF++ ++++L EK
Sbjct: 194 GRKADVWSCGVILFALLVGALPFDDDNLRQLLEK 227
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 153 bits (370), Expect = 1e-36
Identities = 79/214 (36%), Positives = 126/214 (58%), Gaps = 7/214 (3%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK +G+G V H V + +A K+++ K L K + RE+ +L I HP
Sbjct: 21 LEKTLGKGQTGLVKLGVHCVTCQK---VAIKIVNREKLSESVLMK-VEREIAILKLIEHP 76
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
H++ + ++++ + ++ L G+L D+L + G + ++R + RQIIS L + H+ +
Sbjct: 77 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHS 136
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV++G Y
Sbjct: 137 ICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIRGEKYD 193
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEK 239
+ AD+WS GVIL+ +L ALPF++ ++++L EK
Sbjct: 194 GRKADVWSCGVILFALLVGALPFDDDNLRQLLEK 227
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 153 bits (370), Expect = 1e-36
Identities = 79/214 (36%), Positives = 126/214 (58%), Gaps = 7/214 (3%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK +G+G V H V + +A K+++ K L K + RE+ +L I HP
Sbjct: 21 LEKTLGKGQTGLVKLGVHCVTCQK---VAIKIVNREKLSESVLMK-VEREIAILKLIEHP 76
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
H++ + ++++ + ++ L G+L D+L + G + ++R + RQIIS L + H+ +
Sbjct: 77 HVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHS 136
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV++G Y
Sbjct: 137 ICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIRGEKYD 193
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEK 239
+ AD+WS GVIL+ +L ALPF++ ++++L EK
Sbjct: 194 GRKADVWSCGVILFALLVGALPFDDDNLRQLLEK 227
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 150 bits (364), Expect = 6e-36
Identities = 77/229 (33%), Positives = 133/229 (58%), Gaps = 8/229 (3%)
Query: 57 VIDTAKAPRDYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFL 116
+++ K L K + RE+ +L I HPH++ + ++++ + ++ L G+L D+L
Sbjct: 1 IVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL 59
Query: 117 TQNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVR 176
+ G + ++R + RQI+S L + H+ +I HRDLK EN+L+ N++I DFG A
Sbjct: 60 VKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMA---S 116
Query: 177 QRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKL 236
+ D L ET CGS YA PEV+KG Y + ADMWS GVIL+ +L ALPF++ ++++L
Sbjct: 117 LQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQL 176
Query: 237 YEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTW 285
EK +++ F + + + +C+ + ++E EP+ R + + W
Sbjct: 177 LEK--VKRGVFH--MPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 221
>BC032787-1|AAH32787.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 150 bits (363), Expect = 9e-36
Identities = 95/315 (30%), Positives = 159/315 (50%), Gaps = 15/315 (4%)
Query: 1 MGGGDKIDLSTTQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDT 60
MG ++ D S+ + ++ K FI +V+G G++++V+ + + A K I
Sbjct: 1 MGRKEEDDCSSWKKQTTNIR-KTFIFMEVLGSGAFSEVFLVKQRLTG---KLFALKCIKK 56
Query: 61 AKAPRDYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNG 120
+ A RD L E+ VL +I H +IV + +I++ Y++ ++ G+L D + + G
Sbjct: 57 SPAFRD---SSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERG 113
Query: 121 AIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQ 177
E + L ++Q++S ++Y+H I HRDLK EN+L N + ITDFG ++
Sbjct: 114 VYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK---- 169
Query: 178 RDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237
+++ + T CG+ Y APEVL PY K D WSIGVI Y +L PF E + KL+
Sbjct: 170 MEQNGIMSTACGTPGYVAPEVLAQKPY-SKAVDCWSIGVITYILLCGYPPFYEETESKLF 228
Query: 238 EKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTF 297
EK + F + + +S K+ + L+E +P R T + WI ++ L + +
Sbjct: 229 EKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIY 288
Query: 298 LEESLLKQAHEESQK 312
SL Q + K
Sbjct: 289 PSVSLQIQKNFAKSK 303
>AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein.
Length = 460
Score = 150 bits (363), Expect = 9e-36
Identities = 95/315 (30%), Positives = 159/315 (50%), Gaps = 15/315 (4%)
Query: 1 MGGGDKIDLSTTQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDT 60
MG ++ D S+ + ++ K FI +V+G G++++V+ + + A K I
Sbjct: 1 MGRKEEDDCSSWKKQTTNIR-KTFIFMEVLGSGAFSEVFLVKQRLTG---KLFALKCIKK 56
Query: 61 AKAPRDYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNG 120
+ A RD L E+ VL +I H +IV + +I++ Y++ ++ G+L D + + G
Sbjct: 57 SPAFRD---SSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERG 113
Query: 121 AIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQ 177
E + L ++Q++S ++Y+H I HRDLK EN+L N + ITDFG ++
Sbjct: 114 VYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK---- 169
Query: 178 RDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237
+++ + T CG+ Y APEVL PY K D WSIGVI Y +L PF E + KL+
Sbjct: 170 MEQNGIMSTACGTPGYVAPEVLAQKPY-SKAVDCWSIGVITYILLCGYPPFYEETESKLF 228
Query: 238 EKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTF 297
EK + F + + +S K+ + L+E +P R T + WI ++ L + +
Sbjct: 229 EKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIY 288
Query: 298 LEESLLKQAHEESQK 312
SL Q + K
Sbjct: 289 PSVSLQIQKNFAKSK 303
>AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein
protein.
Length = 481
Score = 150 bits (363), Expect = 9e-36
Identities = 95/315 (30%), Positives = 159/315 (50%), Gaps = 15/315 (4%)
Query: 1 MGGGDKIDLSTTQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDT 60
MG ++ D S+ + ++ K FI +V+G G++++V+ + + A K I
Sbjct: 6 MGRKEEDDCSSWKKQTTNIR-KTFIFMEVLGSGAFSEVFLVKQRLTG---KLFALKCIKK 61
Query: 61 AKAPRDYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNG 120
+ A RD L E+ VL +I H +IV + +I++ Y++ ++ G+L D + + G
Sbjct: 62 SPAFRD---SSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERG 118
Query: 121 AIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQ 177
E + L ++Q++S ++Y+H I HRDLK EN+L N + ITDFG ++
Sbjct: 119 VYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK---- 174
Query: 178 RDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237
+++ + T CG+ Y APEVL PY K D WSIGVI Y +L PF E + KL+
Sbjct: 175 MEQNGIMSTACGTPGYVAPEVLAQKPY-SKAVDCWSIGVITYILLCGYPPFYEETESKLF 233
Query: 238 EKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTF 297
EK + F + + +S K+ + L+E +P R T + WI ++ L + +
Sbjct: 234 EKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIY 293
Query: 298 LEESLLKQAHEESQK 312
SL Q + K
Sbjct: 294 PSVSLQIQKNFAKSK 308
>AL023754-3|CAI19991.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 150 bits (363), Expect = 9e-36
Identities = 95/315 (30%), Positives = 159/315 (50%), Gaps = 15/315 (4%)
Query: 1 MGGGDKIDLSTTQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDT 60
MG ++ D S+ + ++ K FI +V+G G++++V+ + + A K I
Sbjct: 1 MGRKEEDDCSSWKKQTTNIR-KTFIFMEVLGSGAFSEVFLVKQRLTG---KLFALKCIKK 56
Query: 61 AKAPRDYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNG 120
+ A RD L E+ VL +I H +IV + +I++ Y++ ++ G+L D + + G
Sbjct: 57 SPAFRD---SSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERG 113
Query: 121 AIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQ 177
E + L ++Q++S ++Y+H I HRDLK EN+L N + ITDFG ++
Sbjct: 114 VYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK---- 169
Query: 178 RDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237
+++ + T CG+ Y APEVL PY K D WSIGVI Y +L PF E + KL+
Sbjct: 170 MEQNGIMSTACGTPGYVAPEVLAQKPY-SKAVDCWSIGVITYILLCGYPPFYEETESKLF 228
Query: 238 EKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTF 297
EK + F + + +S K+ + L+E +P R T + WI ++ L + +
Sbjct: 229 EKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIY 288
Query: 298 LEESLLKQAHEESQK 312
SL Q + K
Sbjct: 289 PSVSLQIQKNFAKSK 303
>AF428261-1|AAL28100.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase I gamma
protein.
Length = 476
Score = 150 bits (363), Expect = 9e-36
Identities = 95/315 (30%), Positives = 159/315 (50%), Gaps = 15/315 (4%)
Query: 1 MGGGDKIDLSTTQSDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDT 60
MG ++ D S+ + ++ K FI +V+G G++++V+ + + A K I
Sbjct: 1 MGRKEEDDCSSWKKQTTNIR-KTFIFMEVLGSGAFSEVFLVKQRLTG---KLFALKCIKK 56
Query: 61 AKAPRDYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNG 120
+ A RD L E+ VL +I H +IV + +I++ Y++ ++ G+L D + + G
Sbjct: 57 SPAFRD---SSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERG 113
Query: 121 AIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQ 177
E + L ++Q++S ++Y+H I HRDLK EN+L N + ITDFG ++
Sbjct: 114 VYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK---- 169
Query: 178 RDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237
+++ + T CG+ Y APEVL PY K D WSIGVI Y +L PF E + KL+
Sbjct: 170 MEQNGIMSTACGTPGYVAPEVLAQKPY-SKAVDCWSIGVITYILLCGYPPFYEETESKLF 228
Query: 238 EKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTF 297
EK + F + + +S K+ + L+E +P R T + WI ++ L + +
Sbjct: 229 EKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIY 288
Query: 298 LEESLLKQAHEESQK 312
SL Q + K
Sbjct: 289 PSVSLQIQKNFAKSK 303
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 150 bits (363), Expect = 9e-36
Identities = 90/284 (31%), Positives = 150/284 (52%), Gaps = 34/284 (11%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 58 LLKTIGKGNFAKVKLARHILTGRE---VAIKIIDKTQLNPTSLQKLF-REVRIMKILNHP 113
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQ------------ 133
+IV + + + ++ + +A G++ D+L +G + E ++R RQ
Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQV 173
Query: 134 -----------IISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDV 182
I+S +QY H I HRDLK EN+L+ A+ N+KI DFGF+ +
Sbjct: 174 SFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGK-- 231
Query: 183 LSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVM 242
+T+CGS YAAPE+ +G Y D+WS+GVILYT+++ +LPF+ ++K+L E+ +
Sbjct: 232 -LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLR 290
Query: 243 RKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
K+R + +ST+C+ + + + P R T + WI
Sbjct: 291 GKYR----IPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWI 330
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 147 bits (356), Expect = 6e-35
Identities = 91/277 (32%), Positives = 141/277 (50%), Gaps = 12/277 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
+IL +G G++ KV H + T H + A K+++ K + + RE+ L
Sbjct: 18 YILGDTLGVGTFGKVKVGKHEL--TGHKV-AVKILNRQKIRSLDVVGKIRREIQNLKLFR 74
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HPHI+ + + + F+ + + G+L D++ +NG + E +SR +QI+SG+ Y H
Sbjct: 75 HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 134
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRDLK ENVL+ A+ N KI DFG + D + L T CGS +YAAPEV+ G
Sbjct: 135 HMVVHRDLKPENVLLDAHMNAKIADFGLSN--MMSDGEFL-RTSCGSPNYAAPEVISGRL 191
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y D+WS GVILY +L LPF++ V L++K + F T L+ +
Sbjct: 192 YAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKK--ICDGIFYTP--QYLNPSVISLL 247
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEE 300
+++ +P R T + W D L K F E+
Sbjct: 248 KHMLQVDPMKRATIKDIREHEWFKQD--LPKYLFPED 282
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 147 bits (355), Expect = 8e-35
Identities = 77/233 (33%), Positives = 134/233 (57%), Gaps = 8/233 (3%)
Query: 53 MACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDL 112
+A K+++ K L K + RE+ +L I HPH++ + ++++ + ++ L G+L
Sbjct: 91 VAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGEL 149
Query: 113 LDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFA 172
D+L + G + ++R + RQIIS L + H+ +I HRDLK EN+L+ N++I DFG A
Sbjct: 150 FDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA 209
Query: 173 RNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETS 232
+ D L ET CGS YA PEV++G Y + AD+WS GVIL+ +L ALPF++ +
Sbjct: 210 ---SLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDN 266
Query: 233 VKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTW 285
+++L EK +++ F + + + +C+ + ++E + R T + W
Sbjct: 267 LRQLLEK--VKRGVFH--MPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIW 315
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 145 bits (352), Expect = 2e-34
Identities = 79/216 (36%), Positives = 120/216 (55%), Gaps = 6/216 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
+IL +G G++ KV H + T H + A K+++ K + + RE+ L
Sbjct: 18 YILGDTLGVGTFGKVKVGKHEL--TGHKV-AVKILNRQKIRSLDVVGKIRREIQNLKLFR 74
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HPHI+ + + + F+ + + G+L D++ +NG + E +SR +QI+SG+ Y H
Sbjct: 75 HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 134
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRDLK ENVL+ A+ N KI DFG + D + L T CGS +YAAPEV+ G
Sbjct: 135 HMVVHRDLKPENVLLDAHMNAKIADFGLSN--MMSDGEFL-RTSCGSPNYAAPEVISGRL 191
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEK 239
Y D+WS GVILY +L LPF++ V L++K
Sbjct: 192 YAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKK 227
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 144 bits (349), Expect = 4e-34
Identities = 85/327 (25%), Positives = 163/327 (49%), Gaps = 11/327 (3%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
++ +IG GS+++V + H ++I K+I+T + + EL VL R+ H
Sbjct: 100 IKALIGRGSFSRVVRVEHRATRQPYAI---KMIETKYREGREVCE---SELRVLRRVRHA 153
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+I+ + +F+ + + ++ + A G+L D + G+ E + ++ ++ G++Y+H +
Sbjct: 154 NIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALG 213
Query: 146 IAHRDLKCENVLV---TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
I HRDLK EN+L + + ITDFG A + R++ D L +T CG+ Y APEVL
Sbjct: 214 ITHRDLKPENLLYYHPGTDSKIIITDFGLA-SARKKGDDCLMKTTCGTPEYIAPEVLVRK 272
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262
PY + DMW++GVI Y +L+ +PF + + +LY + + K+ + +S K+
Sbjct: 273 PYTNSV-DMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDF 331
Query: 263 VTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLKQAHEESQKRDNSTEEDSE 322
+ +L+ +P +R TA W+ + + + L S+ + + + R ST+
Sbjct: 332 IDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQS 391
Query: 323 VERIAELRRKGRGKEGLKVLKNVDANY 349
R + + L+ ++ Y
Sbjct: 392 TRSSRSTRSNKSRRVRERELRELNLRY 418
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 144 bits (349), Expect = 4e-34
Identities = 85/327 (25%), Positives = 163/327 (49%), Gaps = 11/327 (3%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
++ +IG GS+++V + H ++I K+I+T + + EL VL R+ H
Sbjct: 100 IKALIGRGSFSRVVRVEHRATRQPYAI---KMIETKYREGREVCE---SELRVLRRVRHA 153
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+I+ + +F+ + + ++ + A G+L D + G+ E + ++ ++ G++Y+H +
Sbjct: 154 NIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALG 213
Query: 146 IAHRDLKCENVLV---TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
I HRDLK EN+L + + ITDFG A + R++ D L +T CG+ Y APEVL
Sbjct: 214 ITHRDLKPENLLYYHPGTDSKIIITDFGLA-SARKKGDDCLMKTTCGTPEYIAPEVLVRK 272
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262
PY + DMW++GVI Y +L+ +PF + + +LY + + K+ + +S K+
Sbjct: 273 PYTNSV-DMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDF 331
Query: 263 VTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLKQAHEESQKRDNSTEEDSE 322
+ +L+ +P +R TA W+ + + + L S+ + + + R ST+
Sbjct: 332 IDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQS 391
Query: 323 VERIAELRRKGRGKEGLKVLKNVDANY 349
R + + L+ ++ Y
Sbjct: 392 TRSSRSTRSNKSRRVRERELRELNLRY 418
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 144 bits (348), Expect = 6e-34
Identities = 83/267 (31%), Positives = 145/267 (54%), Gaps = 14/267 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L+K +G G +A V A H+ + +A KVID K T L +E+ + + HP
Sbjct: 19 LDKTLGRGHFAVVKLARHVFTGEK---VAVKVIDKTKLDT-LATGHLFQEVRCMKLVQHP 74
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNG-AIPENQSRLWMRQIISGLQYIHTM 144
+IV + + + K ++ L + GD+ D++ ++ + E+ ++ + QI+ + Y H +
Sbjct: 75 NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 134
Query: 145 NIAHRDLKCENVLVTANYN-VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
++ HRDLK ENV+ VK+TDFGF+ + + T CGSL+Y+APE+L G
Sbjct: 135 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDE 191
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y D+WS+GVIL+ ++ PF E + + + K+ TV + +S ECK+ +
Sbjct: 192 YDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKY----TVPSHVSKECKDLI 247
Query: 264 TQLMEPEPKSRPTASAVFNGTWI-GMD 289
T++++ +PK R + + N W+ G+D
Sbjct: 248 TRMLQRDPKRRASLEEIENHPWLQGVD 274
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 144 bits (348), Expect = 6e-34
Identities = 89/332 (26%), Positives = 165/332 (49%), Gaps = 16/332 (4%)
Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIVH 89
IG G++++V H + + + +A K++D K + + L RE+ + +++HP+I+
Sbjct: 80 IGSGNFSQVKLGIHSLTKEK---VAIKILDKTKLDQK-TQRLLSREISSMEKLHHPNIIR 135
Query: 90 VSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHR 149
+ + + +K + + +A G+L ++ G + E +S+L QI+S ++++H I HR
Sbjct: 136 LYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHR 195
Query: 150 DLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLA 209
DLK ENV T+N VK+ DFGF+ ++ + + T+CGS YAAPE+ + Y+
Sbjct: 196 DLKAENVFYTSNTCVKVGDFGFSTVSKKGE---MLNTFCGSPPYAAPELFRDEHYIGIYV 252
Query: 210 DMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEP 269
D+W++GV+LY M+ +PF +V KL +K ++ +V +S C + +++
Sbjct: 253 DIWALGVLLYFMVTGTMPFRAETVAKL-KKSILEG---TYSVPPHVSEPCHRLIRGVLQQ 308
Query: 270 EPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLKQAH--EESQKRDNSTEEDSEVERIA 327
P R + N W+ + T LE L H E S ++ E S +E +
Sbjct: 309 IPTERYGIDCIMNDEWM---QGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLG 365
Query: 328 ELRRKGRGKEGLKVLKNVDANYAKSLYLFENK 359
R +G ++ Y L+ + K
Sbjct: 366 ITEEHIRNNQGRDARSSITGVYRIILHRVQRK 397
>AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 758
Score = 144 bits (348), Expect = 6e-34
Identities = 86/263 (32%), Positives = 144/263 (54%), Gaps = 33/263 (12%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L+K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 62 LQKTIGKGNFAKVKLARHVLTGRE---VAVKIIDKTQLNPTSLQKLF-REVRIMKILNHP 117
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+I G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 118 NI----------------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 155
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ + N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 156 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKKYD 212
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 213 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 268
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
L+ P R + + W+ +
Sbjct: 269 LLVLNPIKRGSLEQIMKDRWMNV 291
>AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein.
Length = 870
Score = 144 bits (348), Expect = 6e-34
Identities = 86/263 (32%), Positives = 144/263 (54%), Gaps = 33/263 (12%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L+K IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 174 LQKTIGKGNFAKVKLARHVLTGRE---VAVKIIDKTQLNPTSLQKLF-REVRIMKILNHP 229
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+I G++ D+L +G + E ++R RQI+S +QY H
Sbjct: 230 NI----------------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 267
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRDLK EN+L+ + N+KI DFGF+ ++ +T+CGS YAAPE+ +G Y
Sbjct: 268 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKKYD 324
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
D+WS+GVILYT+++ +LPF+ ++K+L E+ + K+R + +ST+C+ + +
Sbjct: 325 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKK 380
Query: 266 LMEPEPKSRPTASAVFNGTWIGM 288
L+ P R + + W+ +
Sbjct: 381 LLVLNPIKRGSLEQIMKDRWMNV 403
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 143 bits (347), Expect = 7e-34
Identities = 83/266 (31%), Positives = 136/266 (51%), Gaps = 10/266 (3%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++L +G G++ KV H + T H + A K+++ K + + RE+ L
Sbjct: 16 YVLGDTLGVGTFGKVNIGEHQL--TGHKV-AVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HPHI+ + + +F+ + + G+L D++ ++G + E ++R +QI+S + Y H
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRDLK ENVL+ A+ N KI DFG + D + L T CGS +YAAPEV+ G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSN--MMSDGEFL-RTSCGSPNYAAPEVISGRL 189
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y D+WS GVILY +L LPF++ V L++K +R F + L+ +
Sbjct: 190 YAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKK--IRGGVF--YIPEYLNRSVATLL 245
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMD 289
+++ +P R T + W D
Sbjct: 246 MHMLQVDPLKRATIKDIREHEWFKQD 271
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 143 bits (347), Expect = 7e-34
Identities = 83/266 (31%), Positives = 136/266 (51%), Gaps = 10/266 (3%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++L +G G++ KV H + T H + A K+++ K + + RE+ L
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQL--TGHKV-AVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HPHI+ + + +F+ + + G+L D++ ++G + E ++R +QI+S + Y H
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRDLK ENVL+ A+ N KI DFG + D + L T CGS +YAAPEV+ G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSN--MMSDGEFL-RTSCGSPNYAAPEVISGRL 189
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y D+WS GVILY +L LPF++ V L++K +R F + L+ +
Sbjct: 190 YAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKK--IRGGVF--YIPEYLNRSVATLL 245
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMD 289
+++ +P R T + W D
Sbjct: 246 MHMLQVDPLKRATIKDIREHEWFKQD 271
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 143 bits (347), Expect = 7e-34
Identities = 83/266 (31%), Positives = 136/266 (51%), Gaps = 10/266 (3%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++L +G G++ KV H + T H + A K+++ K + + RE+ L
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQL--TGHKV-AVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HPHI+ + + +F+ + + G+L D++ ++G + E ++R +QI+S + Y H
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRDLK ENVL+ A+ N KI DFG + D + L T CGS +YAAPEV+ G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSN--MMSDGEFL-RTSCGSPNYAAPEVISGRL 189
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y D+WS GVILY +L LPF++ V L++K +R F + L+ +
Sbjct: 190 YAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKK--IRGGVF--YIPEYLNRSVATLL 245
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMD 289
+++ +P R T + W D
Sbjct: 246 MHMLQVDPLKRATIKDIREHEWFKQD 271
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 143 bits (347), Expect = 7e-34
Identities = 83/266 (31%), Positives = 136/266 (51%), Gaps = 10/266 (3%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++L +G G++ KV H + T H + A K+++ K + + RE+ L
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQL--TGHKV-AVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HPHI+ + + +F+ + + G+L D++ ++G + E ++R +QI+S + Y H
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRDLK ENVL+ A+ N KI DFG + D + L T CGS +YAAPEV+ G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSN--MMSDGEFL-RTSCGSPNYAAPEVISGRL 189
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y D+WS GVILY +L LPF++ V L++K +R F + L+ +
Sbjct: 190 YAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKK--IRGGVF--YIPEYLNRSVATLL 245
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMD 289
+++ +P R T + W D
Sbjct: 246 MHMLQVDPLKRATIKDIREHEWFKQD 271
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 143 bits (347), Expect = 7e-34
Identities = 83/266 (31%), Positives = 136/266 (51%), Gaps = 10/266 (3%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++L +G G++ KV H + T H + A K+++ K + + RE+ L
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQL--TGHKV-AVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HPHI+ + + +F+ + + G+L D++ ++G + E ++R +QI+S + Y H
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRDLK ENVL+ A+ N KI DFG + D + L T CGS +YAAPEV+ G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSN--MMSDGEFL-RTSCGSPNYAAPEVISGRL 189
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y D+WS GVILY +L LPF++ V L++K +R F + L+ +
Sbjct: 190 YAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKK--IRGGVF--YIPEYLNRSVATLL 245
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMD 289
+++ +P R T + W D
Sbjct: 246 MHMLQVDPLKRATIKDIREHEWFKQD 271
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 143 bits (346), Expect = 1e-33
Identities = 83/267 (31%), Positives = 144/267 (53%), Gaps = 14/267 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L+K +G G +A V A H+ + +A KVID K T L +E+ + + HP
Sbjct: 18 LDKTLGRGHFAVVKLARHVFTGEK---VAVKVIDKTKLDT-LATGHLFQEVRCMKLVQHP 73
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNG-AIPENQSRLWMRQIISGLQYIHTM 144
+IV + + + K ++ L + GD+ D++ ++ + E+ + + QI+ + Y H +
Sbjct: 74 NIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKL 133
Query: 145 NIAHRDLKCENVLVTANYN-VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
++ HRDLK ENV+ VK+TDFGF+ + + T CGSL+Y+APE+L G
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDE 190
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y D+WS+GVIL+ ++ PF E + + + K+ TV + +S ECK+ +
Sbjct: 191 YDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKY----TVPSHVSKECKDLI 246
Query: 264 TQLMEPEPKSRPTASAVFNGTWI-GMD 289
T++++ +PK R + + N W+ G+D
Sbjct: 247 TRMLQRDPKRRASLEEIENHPWLQGVD 273
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 142 bits (345), Expect = 1e-33
Identities = 83/267 (31%), Positives = 144/267 (53%), Gaps = 14/267 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L+K +G G +A V A H+ + +A KVID K T L +E+ + + HP
Sbjct: 18 LDKTLGRGHFAVVKLARHVFTGEK---VAVKVIDKTKLDT-LATGHLFQEVRCMKLVQHP 73
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNG-AIPENQSRLWMRQIISGLQYIHTM 144
+IV + + + K ++ L + GD+ D++ ++ + E+ ++ + QI+ + Y H +
Sbjct: 74 NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133
Query: 145 NIAHRDLKCENVLVTANYN-VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
++ HRDLK ENV+ VK+TDFGF+ + + T CGSL+Y+APE+L G
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDE 190
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y D+WS+GVIL+ ++ PF E + + + K+ TV + +S ECK+ +
Sbjct: 191 YDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKY----TVPSHVSKECKDLI 246
Query: 264 TQLMEPEPKSRPTASAVFNGTWI-GMD 289
T++++ +PK R + N W+ G+D
Sbjct: 247 TRMLQRDPKRRAYLEEIENHPWLQGVD 273
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 140 bits (339), Expect = 7e-33
Identities = 81/262 (30%), Positives = 134/262 (51%), Gaps = 10/262 (3%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++L +G G++ KV H + T H + A K+++ K + + RE+ L
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQL--TGHKV-AVKILNRQKIRSLDVVGKIKREIQNLKLFR 72
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HPHI+ + + +F+ + + G+L D++ ++G + E ++R +QI+S + Y H
Sbjct: 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRDLK ENVL+ A+ N KI DFG + D + L T CGS +Y APEV+ G
Sbjct: 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSN--MMSDGEFL-RTSCGSPNYTAPEVISGRL 189
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y D+WS GVILY +L LPF++ V L++K +R F + L+ +
Sbjct: 190 YAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKK--IRGGVF--YIPEYLNRSVATLL 245
Query: 264 TQLMEPEPKSRPTASAVFNGTW 285
+++ +P R T + W
Sbjct: 246 MHMLQVDPLKRATIKDIREHEW 267
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 138 bits (334), Expect = 3e-32
Identities = 82/269 (30%), Positives = 139/269 (51%), Gaps = 12/269 (4%)
Query: 29 VIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIV 88
V+G G++++V A D+ ++A K I AK + + E+ VL +I HP+IV
Sbjct: 25 VLGTGAFSEVILAE---DKRTQKLVAIKCI--AKEALEGKEGSMENEIAVLHKIKHPNIV 79
Query: 89 HVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAH 148
+ +I++ ++ ++ G+L D + + G E + + Q++ ++Y+H + I H
Sbjct: 80 ALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVH 139
Query: 149 RDLKCENVL---VTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
RDLK EN+L + + + I+DFG + + D + T CG+ Y APEVL PY
Sbjct: 140 RDLKPENLLYYSLDEDSKIMISDFGLS---KMEDPGSVLSTACGTPGYVAPEVLAQKPY- 195
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S K+ +
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRH 255
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
LME +P+ R T WI D+ L K
Sbjct: 256 LMEKDPEKRFTCEQALQHPWIAGDTALDK 284
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 138 bits (334), Expect = 3e-32
Identities = 82/269 (30%), Positives = 139/269 (51%), Gaps = 12/269 (4%)
Query: 29 VIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIV 88
V+G G++++V A D+ ++A K I AK + + E+ VL +I HP+IV
Sbjct: 25 VLGTGAFSEVILAE---DKRTQKLVAIKCI--AKEALEGKEGSMENEIAVLHKIKHPNIV 79
Query: 89 HVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAH 148
+ +I++ ++ ++ G+L D + + G E + + Q++ ++Y+H + I H
Sbjct: 80 ALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVH 139
Query: 149 RDLKCENVL---VTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
RDLK EN+L + + + I+DFG + + D + T CG+ Y APEVL PY
Sbjct: 140 RDLKPENLLYYSLDEDSKIMISDFGLS---KMEDPGSVLSTACGTPGYVAPEVLAQKPY- 195
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S K+ +
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRH 255
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
LME +P+ R T WI D+ L K
Sbjct: 256 LMEKDPEKRFTCEQALQHPWIAGDTALDK 284
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 138 bits (334), Expect = 3e-32
Identities = 82/269 (30%), Positives = 139/269 (51%), Gaps = 12/269 (4%)
Query: 29 VIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIV 88
V+G G++++V A D+ ++A K I AK + + E+ VL +I HP+IV
Sbjct: 25 VLGTGAFSEVILAE---DKRTQKLVAIKCI--AKEALEGKEGSMENEIAVLHKIKHPNIV 79
Query: 89 HVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAH 148
+ +I++ ++ ++ G+L D + + G E + + Q++ ++Y+H + I H
Sbjct: 80 ALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVH 139
Query: 149 RDLKCENVL---VTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
RDLK EN+L + + + I+DFG + + D + T CG+ Y APEVL PY
Sbjct: 140 RDLKPENLLYYSLDEDSKIMISDFGLS---KMEDPGSVLSTACGTPGYVAPEVLAQKPY- 195
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S K+ +
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRH 255
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
LME +P+ R T WI D+ L K
Sbjct: 256 LMEKDPEKRFTCEQALQHPWIAGDTALDK 284
>AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens
cDNA FLJ90097 fis, clone HEMBA1005929, weakly similar to
H.sapiens mRNA for serine/threonine protein kinase EMK.
).
Length = 426
Score = 138 bits (334), Expect = 3e-32
Identities = 68/185 (36%), Positives = 109/185 (58%), Gaps = 7/185 (3%)
Query: 104 LRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYN 163
+ +A G++ D+L +G + E ++R RQI+S + Y H NI HRDLK EN+L+ A N
Sbjct: 1 MEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEAN 60
Query: 164 VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLN 223
+KI DFGF+ + +T+CGS YAAPE+ +G Y D+WS+GVILYT+++
Sbjct: 61 IKIADFGFSNEFTLGSK---LDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVS 117
Query: 224 KALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNG 283
+LPF+ ++K+L E+ + K+R V +ST+C+ + + + P R T +
Sbjct: 118 GSLPFDGHNLKELRERVLRGKYR----VPFYMSTDCESILRRFLVLNPAKRCTLEQIMKD 173
Query: 284 TWIGM 288
WI +
Sbjct: 174 KWINI 178
>BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2
(Drosophila) protein.
Length = 685
Score = 136 bits (328), Expect = 1e-31
Identities = 73/255 (28%), Positives = 136/255 (53%), Gaps = 10/255 (3%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR 81
K + KV+G+G +AK Y+ M D T + + A K+I ++ + + + + +E+++
Sbjct: 80 KRYCRGKVLGKGGFAKCYE---MTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRI 136
Query: 82 INHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
++H H+V + F+ + +I L + + L + E + R ++RQI+SGL+Y+
Sbjct: 137 LHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYL 196
Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKG 201
H I HRDLK N + +K+ DFG A R + T CG+ +Y +PEVL
Sbjct: 197 HEQEILHRDLKLGNFFINEAMELKVGDFGLA--ARLEPLEHRRRTICGTPNYLSPEVLNK 254
Query: 202 VPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKE 261
+ + +D+W++G ++YTML PF T++K+ Y + +R+ R+ T+ + L K
Sbjct: 255 QGHGCE-SDIWALGCVMYTMLLGRPPFETTNLKETY--RCIREARY--TMPSSLLAPAKH 309
Query: 262 QVTQLMEPEPKSRPT 276
+ ++ P+ RP+
Sbjct: 310 LIASMLSKNPEDRPS 324
>AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens
cDNA FLJ40844 fis, clone TRACH2014356, highly similar to
SERINE/THREONINE-PROTEIN KINASE SNK (EC 2.7.1.-). ).
Length = 372
Score = 136 bits (328), Expect = 1e-31
Identities = 73/255 (28%), Positives = 136/255 (53%), Gaps = 10/255 (3%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR 81
K + KV+G+G +AK Y+ M D T + + A K+I ++ + + + + +E+++
Sbjct: 73 KRYCRGKVLGKGGFAKCYE---MTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRI 129
Query: 82 INHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
++H H+V + F+ + +I L + + L + E + R ++RQI+SGL+Y+
Sbjct: 130 LHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYL 189
Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKG 201
H I HRDLK N + +K+ DFG A R + T CG+ +Y +PEVL
Sbjct: 190 HEQEILHRDLKLGNFFINEAMELKVGDFGLA--ARLEPLEHRRRTICGTPNYLSPEVLNK 247
Query: 202 VPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKE 261
+ + +D+W++G ++YTML PF T++K+ Y + +R+ R+ T+ + L K
Sbjct: 248 QGHGCE-SDIWALGCVMYTMLLGRPPFETTNLKETY--RCIREARY--TMPSSLLAPAKH 302
Query: 262 QVTQLMEPEPKSRPT 276
+ ++ P+ RP+
Sbjct: 303 LIASMLSKNPEDRPS 317
>AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens
cDNA FLJ14587 fis, clone NT2RM4001758, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK
(EC 2.7.1.-). ).
Length = 638
Score = 136 bits (328), Expect = 1e-31
Identities = 65/185 (35%), Positives = 111/185 (60%), Gaps = 7/185 (3%)
Query: 104 LRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYN 163
+ +A G++ D+L +G + E ++R RQI+S +QY H I HRDLK EN+L+ + N
Sbjct: 1 MEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMN 60
Query: 164 VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLN 223
+KI DFGF+ ++ +T+CGS YAAPE+ +G Y D+WS+GVILYT+++
Sbjct: 61 IKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 117
Query: 224 KALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNG 283
+LPF+ ++K+L E+ + K+R + +ST+C+ + +L+ P R + +
Sbjct: 118 GSLPFDGQNLKELRERVLRGKYR----IPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKD 173
Query: 284 TWIGM 288
W+ +
Sbjct: 174 RWMNV 178
>AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 603
Score = 136 bits (328), Expect = 1e-31
Identities = 63/158 (39%), Positives = 100/158 (63%), Gaps = 3/158 (1%)
Query: 82 INHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
I HPH++ + ++++ + ++ L G+L D+L + G + ++R + RQIIS L +
Sbjct: 2 IEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFC 61
Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKG 201
H+ +I HRDLK EN+L+ N++I DFG A + D L ET CGS YA PEV++G
Sbjct: 62 HSHSICHRDLKPENLLLDEKNNIRIADFGMA---SLQVGDSLLETSCGSPHYACPEVIRG 118
Query: 202 VPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEK 239
Y + AD+WS GVIL+ +L ALPF++ ++++L EK
Sbjct: 119 EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEK 156
>AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 136 bits (328), Expect = 1e-31
Identities = 73/255 (28%), Positives = 136/255 (53%), Gaps = 10/255 (3%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR 81
K + KV+G+G +AK Y+ M D T + + A K+I ++ + + + + +E+++
Sbjct: 80 KRYCRGKVLGKGGFAKCYE---MTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRI 136
Query: 82 INHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
++H H+V + F+ + +I L + + L + E + R ++RQI+SGL+Y+
Sbjct: 137 LHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYL 196
Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKG 201
H I HRDLK N + +K+ DFG A R + T CG+ +Y +PEVL
Sbjct: 197 HEQEILHRDLKLGNFFINEAMELKVGDFGLA--ARLEPLEHRRRTICGTPNYLSPEVLNK 254
Query: 202 VPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKE 261
+ + +D+W++G ++YTML PF T++K+ Y + +R+ R+ T+ + L K
Sbjct: 255 QGHGCE-SDIWALGCVMYTMLLGRPPFETTNLKETY--RCIREARY--TMPSSLLAPAKH 309
Query: 262 QVTQLMEPEPKSRPT 276
+ ++ P+ RP+
Sbjct: 310 LIASMLSKNPEDRPS 324
>AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 136 bits (328), Expect = 1e-31
Identities = 73/255 (28%), Positives = 136/255 (53%), Gaps = 10/255 (3%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR 81
K + KV+G+G +AK Y+ M D T + + A K+I ++ + + + + +E+++
Sbjct: 80 KRYCRGKVLGKGGFAKCYE---MTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRI 136
Query: 82 INHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
++H H+V + F+ + +I L + + L + E + R ++RQI+SGL+Y+
Sbjct: 137 LHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYL 196
Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKG 201
H I HRDLK N + +K+ DFG A R + T CG+ +Y +PEVL
Sbjct: 197 HEQEILHRDLKLGNFFINEAMELKVGDFGLA--ARLEPLEHRRRTICGTPNYLSPEVLNK 254
Query: 202 VPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKE 261
+ + +D+W++G ++YTML PF T++K+ Y + +R+ R+ T+ + L K
Sbjct: 255 QGHGCE-SDIWALGCVMYTMLLGRPPFETTNLKETY--RCIREARY--TMPSSLLAPAKH 309
Query: 262 QVTQLMEPEPKSRPT 276
+ ++ P+ RP+
Sbjct: 310 LIASMLSKNPEDRPS 324
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 135 bits (327), Expect = 2e-31
Identities = 67/179 (37%), Positives = 106/179 (59%), Gaps = 7/179 (3%)
Query: 110 GDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDF 169
G++ D+L +G + E ++R RQI+S + Y H NI HRDLK EN+L+ A N+KI DF
Sbjct: 171 GEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADF 230
Query: 170 GFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFN 229
GF+ + +T+CGS YAAPE+ +G Y D+WS+GVILYT+++ +LPF+
Sbjct: 231 GFSNEFTLGSK---LDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFD 287
Query: 230 ETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGM 288
++K+L E+ + K+R V +ST+C+ + + + P R T + WI +
Sbjct: 288 GHNLKELRERVLRGKYR----VPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINI 342
Score = 43.6 bits (98), Expect = 0.001
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 4/86 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + IG+G++AKV A H++ +A K+ID + L K RE+ ++ +NHP
Sbjct: 61 LLRTIGKGNFAKVKLARHILTGRE---VAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHP 116
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGD 111
+IV + + + ++ + +A G+
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGE 142
>U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine
protein kinase PRK protein.
Length = 607
Score = 135 bits (326), Expect = 3e-31
Identities = 79/259 (30%), Positives = 134/259 (51%), Gaps = 14/259 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++ +++G+G +A+ Y+AT D S A KVI ++ + + + + E+++ +
Sbjct: 23 YLKGRLLGKGGFARCYEAT---DTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQ 79
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
H HIV S+ F+ +IFL L + E + R ++RQI+SGL+Y+H
Sbjct: 80 HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQ 139
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK N +T N +K+ DFG A R + +T CG+ +Y APEVL
Sbjct: 140 RGILHRDLKLGNFFITENMELKVGDFGLA--ARLEPPEQRKKTICGTPNYVAPEVLLRQG 197
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYE--KQVMRKWRFRTTVVNQLSTECKE 261
+ P+ AD+WS+G ++YT+L + PF +K+ Y KQV T+ LS ++
Sbjct: 198 HGPE-ADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQV------HYTLPASLSLPARQ 250
Query: 262 QVTQLMEPEPKSRPTASAV 280
+ ++ P+ RP+ +
Sbjct: 251 LLAAILRASPRDRPSIDQI 269
>BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 135 bits (326), Expect = 3e-31
Identities = 79/259 (30%), Positives = 134/259 (51%), Gaps = 14/259 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++ +++G+G +A+ Y+AT D S A KVI ++ + + + + E+++ +
Sbjct: 62 YLKGRLLGKGGFARCYEAT---DTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQ 118
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
H HIV S+ F+ +IFL L + E + R ++RQI+SGL+Y+H
Sbjct: 119 HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQ 178
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK N +T N +K+ DFG A R + +T CG+ +Y APEVL
Sbjct: 179 RGILHRDLKLGNFFITENMELKVGDFGLA--ARLEPPEQRKKTICGTPNYVAPEVLLRQG 236
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYE--KQVMRKWRFRTTVVNQLSTECKE 261
+ P+ AD+WS+G ++YT+L + PF +K+ Y KQV T+ LS ++
Sbjct: 237 HGPE-ADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQV------HYTLPASLSLPARQ 289
Query: 262 QVTQLMEPEPKSRPTASAV 280
+ ++ P+ RP+ +
Sbjct: 290 LLAAILRASPRDRPSIDQI 308
>AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 135 bits (326), Expect = 3e-31
Identities = 79/259 (30%), Positives = 134/259 (51%), Gaps = 14/259 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++ +++G+G +A+ Y+AT D S A KVI ++ + + + + E+++ +
Sbjct: 62 YLKGRLLGKGGFARCYEAT---DTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQ 118
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
H HIV S+ F+ +IFL L + E + R ++RQI+SGL+Y+H
Sbjct: 119 HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQ 178
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK N +T N +K+ DFG A R + +T CG+ +Y APEVL
Sbjct: 179 RGILHRDLKLGNFFITENMELKVGDFGLA--ARLEPPEQRKKTICGTPNYVAPEVLLRQG 236
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYE--KQVMRKWRFRTTVVNQLSTECKE 261
+ P+ AD+WS+G ++YT+L + PF +K+ Y KQV T+ LS ++
Sbjct: 237 HGPE-ADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQV------HYTLPASLSLPARQ 289
Query: 262 QVTQLMEPEPKSRPTASAV 280
+ ++ P+ RP+ +
Sbjct: 290 LLAAILRASPRDRPSIDQI 308
>AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 135 bits (326), Expect = 3e-31
Identities = 79/259 (30%), Positives = 134/259 (51%), Gaps = 14/259 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++ +++G+G +A+ Y+AT D S A KVI ++ + + + + E+++ +
Sbjct: 62 YLKGRLLGKGGFARCYEAT---DTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQ 118
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
H HIV S+ F+ +IFL L + E + R ++RQI+SGL+Y+H
Sbjct: 119 HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQ 178
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK N +T N +K+ DFG A R + +T CG+ +Y APEVL
Sbjct: 179 RGILHRDLKLGNFFITENMELKVGDFGLA--ARLEPPEQRKKTICGTPNYVAPEVLLRQG 236
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYE--KQVMRKWRFRTTVVNQLSTECKE 261
+ P+ AD+WS+G ++YT+L + PF +K+ Y KQV T+ LS ++
Sbjct: 237 HGPE-ADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQV------HYTLPASLSLPARQ 289
Query: 262 QVTQLMEPEPKSRPTASAV 280
+ ++ P+ RP+ +
Sbjct: 290 LLAAILRASPRDRPSIDQI 308
>AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 variant
protein.
Length = 621
Score = 135 bits (326), Expect = 3e-31
Identities = 79/259 (30%), Positives = 134/259 (51%), Gaps = 14/259 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++ +++G+G +A+ Y+AT D S A KVI ++ + + + + E+++ +
Sbjct: 37 YLKGRLLGKGGFARCYEAT---DTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQ 93
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
H HIV S+ F+ +IFL L + E + R ++RQI+SGL+Y+H
Sbjct: 94 HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQ 153
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK N +T N +K+ DFG A R + +T CG+ +Y APEVL
Sbjct: 154 RGILHRDLKLGNFFITENMELKVGDFGLA--ARLEPPEQRKKTICGTPNYVAPEVLLRQG 211
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYE--KQVMRKWRFRTTVVNQLSTECKE 261
+ P+ AD+WS+G ++YT+L + PF +K+ Y KQV T+ LS ++
Sbjct: 212 HGPE-ADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQV------HYTLPASLSLPARQ 264
Query: 262 QVTQLMEPEPKSRPTASAV 280
+ ++ P+ RP+ +
Sbjct: 265 LLAAILRASPRDRPSIDQI 283
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 134 bits (325), Expect = 3e-31
Identities = 85/277 (30%), Positives = 143/277 (51%), Gaps = 12/277 (4%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
+K F ++ +G G++++V A ++ + A K I KA + + + E+ VL
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAE---EKATGKLFAVKCIPK-KALKGKESS-IENEIAVLR 74
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+I H +IV + +I++ ++ ++ G+L D + + G E + +RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 141 IHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
+H M I HRDLK EN+L + + I+DFG ++ + DV+S T CG+ Y APE
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS-TACGTPGYVAPE 191
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL PY K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S
Sbjct: 192 VLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
K+ + LME +P R T WI D+ L K
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 134 bits (325), Expect = 3e-31
Identities = 85/277 (30%), Positives = 143/277 (51%), Gaps = 12/277 (4%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
+K F ++ +G G++++V A ++ + A K I KA + + + E+ VL
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAE---EKATGKLFAVKCIPK-KALKGKESS-IENEIAVLR 74
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+I H +IV + +I++ ++ ++ G+L D + + G E + +RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 141 IHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
+H M I HRDLK EN+L + + I+DFG ++ + DV+S T CG+ Y APE
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS-TACGTPGYVAPE 191
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL PY K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S
Sbjct: 192 VLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
K+ + LME +P R T WI D+ L K
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 134 bits (325), Expect = 3e-31
Identities = 85/277 (30%), Positives = 143/277 (51%), Gaps = 12/277 (4%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
+K F ++ +G G++++V A ++ + A K I KA + + + E+ VL
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAE---EKATGKLFAVKCIPK-KALKGKESS-IENEIAVLR 74
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+I H +IV + +I++ ++ ++ G+L D + + G E + +RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 141 IHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
+H M I HRDLK EN+L + + I+DFG ++ + DV+S T CG+ Y APE
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS-TACGTPGYVAPE 191
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL PY K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S
Sbjct: 192 VLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
K+ + LME +P R T WI D+ L K
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 134 bits (325), Expect = 3e-31
Identities = 85/277 (30%), Positives = 143/277 (51%), Gaps = 12/277 (4%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
+K F ++ +G G++++V A ++ + A K I KA + + + E+ VL
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAE---EKATGKLFAVKCIPK-KALKGKESS-IENEIAVLR 74
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+I H +IV + +I++ ++ ++ G+L D + + G E + +RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 141 IHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
+H M I HRDLK EN+L + + I+DFG ++ + DV+S T CG+ Y APE
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS-TACGTPGYVAPE 191
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL PY K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S
Sbjct: 192 VLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
K+ + LME +P R T WI D+ L K
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 134 bits (325), Expect = 3e-31
Identities = 85/277 (30%), Positives = 143/277 (51%), Gaps = 12/277 (4%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
+K F ++ +G G++++V A ++ + A K I KA + + + E+ VL
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAE---EKATGKLFAVKCIPK-KALKGKESS-IENEIAVLR 74
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+I H +IV + +I++ ++ ++ G+L D + + G E + +RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 141 IHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
+H M I HRDLK EN+L + + I+DFG ++ + DV+S T CG+ Y APE
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS-TACGTPGYVAPE 191
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL PY K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S
Sbjct: 192 VLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
K+ + LME +P R T WI D+ L K
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 134 bits (325), Expect = 3e-31
Identities = 85/277 (30%), Positives = 143/277 (51%), Gaps = 12/277 (4%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
+K F ++ +G G++++V A ++ + A K I KA + + + E+ VL
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAE---EKATGKLFAVKCIPK-KALKGKESS-IENEIAVLR 74
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+I H +IV + +I++ ++ ++ G+L D + + G E + +RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 141 IHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
+H M I HRDLK EN+L + + I+DFG ++ + DV+S T CG+ Y APE
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS-TACGTPGYVAPE 191
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL PY K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S
Sbjct: 192 VLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
K+ + LME +P R T WI D+ L K
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 134 bits (325), Expect = 3e-31
Identities = 85/277 (30%), Positives = 143/277 (51%), Gaps = 12/277 (4%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
+K F ++ +G G++++V A ++ + A K I KA + + + E+ VL
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAE---EKATGKLFAVKCIPK-KALKGKESS-IENEIAVLR 74
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+I H +IV + +I++ ++ ++ G+L D + + G E + +RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 141 IHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
+H M I HRDLK EN+L + + I+DFG ++ + DV+S T CG+ Y APE
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS-TACGTPGYVAPE 191
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL PY K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S
Sbjct: 192 VLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
K+ + LME +P R T WI D+ L K
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 134 bits (325), Expect = 3e-31
Identities = 85/277 (30%), Positives = 143/277 (51%), Gaps = 12/277 (4%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
+K F ++ +G G++++V A ++ + A K I KA + + + E+ VL
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAE---EKATGKLFAVKCIPK-KALKGKESS-IENEIAVLR 74
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+I H +IV + +I++ ++ ++ G+L D + + G E + +RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 141 IHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
+H M I HRDLK EN+L + + I+DFG ++ + DV+S T CG+ Y APE
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS-TACGTPGYVAPE 191
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL PY K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S
Sbjct: 192 VLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
K+ + LME +P R T WI D+ L K
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 134 bits (325), Expect = 3e-31
Identities = 85/277 (30%), Positives = 143/277 (51%), Gaps = 12/277 (4%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
+K F ++ +G G++++V A ++ + A K I KA + + + E+ VL
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAE---EKATGKLFAVKCIPK-KALKGKESS-IENEIAVLR 74
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+I H +IV + +I++ ++ ++ G+L D + + G E + +RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 141 IHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
+H M I HRDLK EN+L + + I+DFG ++ + DV+S T CG+ Y APE
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS-TACGTPGYVAPE 191
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL PY K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S
Sbjct: 192 VLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
K+ + LME +P R T WI D+ L K
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
>AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine
protein kinase protein.
Length = 646
Score = 134 bits (325), Expect = 3e-31
Identities = 79/259 (30%), Positives = 134/259 (51%), Gaps = 14/259 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
++ +++G+G +A+ Y+AT D S A KVI ++ + + + + E+++ +
Sbjct: 62 YLKGRLLGKGGFARCYEAT---DTETGSAYAVKVIPQSRVVKPHQREKILNEIELHRDLQ 118
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
H HIV S+ F+ +IFL L + E + R ++RQI+SGL+Y+H
Sbjct: 119 HRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQ 178
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK N +T N +K+ DFG A R + +T CG+ +Y APEVL
Sbjct: 179 RGILHRDLKLGNFFITENMELKVGDFGLA--ARLEPPEQRKKTICGTPNYVAPEVLLRQG 236
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYE--KQVMRKWRFRTTVVNQLSTECKE 261
+ P+ AD+WS+G ++YT+L + PF +K+ Y KQV T+ LS ++
Sbjct: 237 HGPE-ADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQV------HYTLPASLSLPARQ 289
Query: 262 QVTQLMEPEPKSRPTASAV 280
+ ++ P+ RP+ +
Sbjct: 290 LLAAILRASPRDRPSIDQI 308
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 134 bits (325), Expect = 3e-31
Identities = 85/277 (30%), Positives = 143/277 (51%), Gaps = 12/277 (4%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
+K F ++ +G G++++V A ++ + A K I KA + + + E+ VL
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAE---EKATGKLFAVKCIPK-KALKGKESS-IENEIAVLR 74
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+I H +IV + +I++ ++ ++ G+L D + + G E + +RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 141 IHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
+H M I HRDLK EN+L + + I+DFG ++ + DV+S T CG+ Y APE
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS-TACGTPGYVAPE 191
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL PY K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S
Sbjct: 192 VLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
K+ + LME +P R T WI D+ L K
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 134 bits (325), Expect = 3e-31
Identities = 85/277 (30%), Positives = 143/277 (51%), Gaps = 12/277 (4%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
+K F ++ +G G++++V A ++ + A K I KA + + + E+ VL
Sbjct: 20 KKIFEFKETLGTGAFSEVVLAE---EKATGKLFAVKCIPK-KALKGKESS-IENEIAVLR 74
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+I H +IV + +I++ ++ ++ G+L D + + G E + +RQ++ + Y
Sbjct: 75 KIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYY 134
Query: 141 IHTMNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
+H M I HRDLK EN+L + + I+DFG ++ + DV+S T CG+ Y APE
Sbjct: 135 LHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS-TACGTPGYVAPE 191
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
VL PY K D WSIGVI Y +L PF + + KL+E+ + ++ F + + +S
Sbjct: 192 VLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISD 250
Query: 258 ECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAK 294
K+ + LME +P R T WI D+ L K
Sbjct: 251 SAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNK 287
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 132 bits (320), Expect = 1e-30
Identities = 84/271 (30%), Positives = 146/271 (53%), Gaps = 17/271 (6%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIM--ACKVIDTAKAPRDYLTKFLPRELDVLIR 81
F + ++G+GS+A VY+A E+ HS + A K+ID + + + + E+ + +
Sbjct: 12 FKVGNLLGKGSFAGVYRA-----ESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQ 66
Query: 82 INHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIP--ENQSRLWMRQIISGLQ 139
+ HP I+ + N F+ ++ L NG++ +L +N P EN++R +M QII+G+
Sbjct: 67 LKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYL-KNRVKPFSENEARHFMHQIITGML 125
Query: 140 YIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL 199
Y+H+ I HRDL N+L+T N N+KI DFG A ++ T CG+ +Y +PE+
Sbjct: 126 YLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEK--HYTLCGTPNYISPEIA 183
Query: 200 KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTEC 259
+ + +D+WS+G + YT+L PF+ +VK K V+ + T LS E
Sbjct: 184 TRSAHGLE-SDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTF----LSIEA 238
Query: 260 KEQVTQLMEPEPKSRPTASAVFNGTWIGMDS 290
K+ + QL+ P R + S+V + ++ +S
Sbjct: 239 KDLIHQLLRRNPADRLSLSSVLDHPFMSRNS 269
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 132 bits (319), Expect = 2e-30
Identities = 65/224 (29%), Positives = 126/224 (56%), Gaps = 4/224 (1%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F K++GEGS++ V A + ++I K+++ ++ ++ RE DV+ R++
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAI---KILEKRHIIKENKVPYVTRERDVMSRLD 138
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP V + FQ K + L +A+NG+LL ++ + G+ E +R + +I+S L+Y+H
Sbjct: 139 HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 198
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK EN+L+ + +++ITDFG A+ + + + ++ G+ Y +PE+L
Sbjct: 199 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 258
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRF 247
K +D+W++G I+Y ++ PF + +++K + ++ F
Sbjct: 259 AC-KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDF 301
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 132 bits (319), Expect = 2e-30
Identities = 65/224 (29%), Positives = 126/224 (56%), Gaps = 4/224 (1%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F K++GEGS++ V A + ++I K+++ ++ ++ RE DV+ R++
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAI---KILEKRHIIKENKVPYVTRERDVMSRLD 138
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP V + FQ K + L +A+NG+LL ++ + G+ E +R + +I+S L+Y+H
Sbjct: 139 HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 198
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK EN+L+ + +++ITDFG A+ + + + ++ G+ Y +PE+L
Sbjct: 199 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 258
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRF 247
K +D+W++G I+Y ++ PF + +++K + ++ F
Sbjct: 259 AC-KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDF 301
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 132 bits (319), Expect = 2e-30
Identities = 65/224 (29%), Positives = 126/224 (56%), Gaps = 4/224 (1%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F K++GEGS++ V A + ++I K+++ ++ ++ RE DV+ R++
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAI---KILEKRHIIKENKVPYVTRERDVMSRLD 138
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP V + FQ K + L +A+NG+LL ++ + G+ E +R + +I+S L+Y+H
Sbjct: 139 HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 198
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK EN+L+ + +++ITDFG A+ + + + ++ G+ Y +PE+L
Sbjct: 199 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 258
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRF 247
K +D+W++G I+Y ++ PF + +++K + ++ F
Sbjct: 259 AC-KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDF 301
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 132 bits (319), Expect = 2e-30
Identities = 65/224 (29%), Positives = 126/224 (56%), Gaps = 4/224 (1%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F K++GEGS++ V A + ++I K+++ ++ ++ RE DV+ R++
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAI---KILEKRHIIKENKVPYVTRERDVMSRLD 138
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP V + FQ K + L +A+NG+LL ++ + G+ E +R + +I+S L+Y+H
Sbjct: 139 HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 198
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK EN+L+ + +++ITDFG A+ + + + ++ G+ Y +PE+L
Sbjct: 199 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 258
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRF 247
K +D+W++G I+Y ++ PF + +++K + ++ F
Sbjct: 259 AC-KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDF 301
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 132 bits (319), Expect = 2e-30
Identities = 65/224 (29%), Positives = 126/224 (56%), Gaps = 4/224 (1%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F K++GEGS++ V A + ++I K+++ ++ ++ RE DV+ R++
Sbjct: 74 FKFGKILGEGSFSTVVLARELATSREYAI---KILEKRHIIKENKVPYVTRERDVMSRLD 130
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP V + FQ K + L +A+NG+LL ++ + G+ E +R + +I+S L+Y+H
Sbjct: 131 HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 190
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK EN+L+ + +++ITDFG A+ + + + ++ G+ Y +PE+L
Sbjct: 191 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 250
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRF 247
K +D+W++G I+Y ++ PF + +++K + ++ F
Sbjct: 251 AC-KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDF 293
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 132 bits (319), Expect = 2e-30
Identities = 65/224 (29%), Positives = 126/224 (56%), Gaps = 4/224 (1%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F K++GEGS++ V A + ++I K+++ ++ ++ RE DV+ R++
Sbjct: 120 FKFGKILGEGSFSTVVLARELATSREYAI---KILEKRHIIKENKVPYVTRERDVMSRLD 176
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP V + FQ K + L +A+NG+LL ++ + G+ E +R + +I+S L+Y+H
Sbjct: 177 HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 236
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK EN+L+ + +++ITDFG A+ + + + ++ G+ Y +PE+L
Sbjct: 237 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 296
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRF 247
K +D+W++G I+Y ++ PF + +++K + ++ F
Sbjct: 297 AC-KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDF 339
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 131 bits (317), Expect = 3e-30
Identities = 81/269 (30%), Positives = 143/269 (53%), Gaps = 13/269 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + ++G+GS+A VY+A + +A K+ID + + + + E+ + ++
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLE---VAIKMIDKKAMYKAGMVQRVKNEVKIHCQLK 68
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIP--ENQSRLWMRQIISGLQYI 141
HP I+ + N F+ ++ L NG++ +L +N P EN++R +M QII+G+ Y+
Sbjct: 69 HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYL-KNRVKPFSENEARHFMHQIITGMLYL 127
Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKG 201
H+ I HRDL N+L+T N N+KI DFG A ++ T CG+ +Y +PE+
Sbjct: 128 HSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEK--HYTLCGTPNYISPEIATR 185
Query: 202 VPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKE 261
+ + +D+WS+G + YT+L PF+ +VK K V+ + T LS E K+
Sbjct: 186 SAHGLE-SDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTF----LSIEAKD 240
Query: 262 QVTQLMEPEPKSRPTASAVFNGTWIGMDS 290
+ QL+ P R + S+V + ++ +S
Sbjct: 241 LIHQLLRRNPADRLSLSSVLDHPFMSRNS 269
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 131 bits (317), Expect = 3e-30
Identities = 91/292 (31%), Positives = 142/292 (48%), Gaps = 27/292 (9%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
+IL +G G++ KV H + T H + A K+++ K + + RE+ L
Sbjct: 27 YILGDTLGVGTFGKVKVGKHEL--TGHKV-AVKILNRQKIRSLDVVGKIRREIQNLKLFR 83
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGA---------------IPENQSR 128
HPHI+ + + + F+ + + G+L D++ +NG + E +SR
Sbjct: 84 HPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELDEKESR 143
Query: 129 LWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYC 188
+QI+SG+ Y H + HRDLK ENVL+ A+ N KI DFG + + D + L T C
Sbjct: 144 RLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS--DGEFL-RTSC 200
Query: 189 GSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFR 248
GS +YAAPEV+ G Y D+WS GVILY +L LPF++ V L++K + F
Sbjct: 201 GSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKK--ICDGIFY 258
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEE 300
T L+ + +++ +P R T + W D L K F E+
Sbjct: 259 TP--QYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQD--LPKYLFPED 306
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 131 bits (316), Expect = 4e-30
Identities = 71/206 (34%), Positives = 112/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GSY KV+ + + A KV+ A RD + + R D+L +
Sbjct: 60 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMER--DILAEV 117
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 118 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 177
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++KITDFG ++ D+ S +CG++ Y APEV+
Sbjct: 178 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYS--FCGTIEYMAPEVVNRR 235
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML ALPF
Sbjct: 236 GH-TQSADWWSFGVLMFEMLTGALPF 260
Score = 59.7 bits (138), Expect = 2e-08
Identities = 34/136 (25%), Positives = 70/136 (51%), Gaps = 11/136 (8%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H +T +++ K+I K+ RD E+++L+R
Sbjct: 415 GYEIKEDIGVGSYSVCKRCVHKATDTEYAV---KII--GKSKRDP-----SEEIEILLRY 464
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I + Y+
Sbjct: 465 GQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYL 524
Query: 142 HTMNIAHRDLKCENVL 157
H+ + HRDLK N+L
Sbjct: 525 HSQGVVHRDLKPSNIL 540
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 131 bits (316), Expect = 4e-30
Identities = 65/224 (29%), Positives = 125/224 (55%), Gaps = 4/224 (1%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F K++GEGS++ V A + ++I K+++ ++ ++ RE DV+ R++
Sbjct: 55 FKFGKILGEGSFSTVVLARELATSREYAI---KILEKRHIIKENKVPYVTRERDVMSRLD 111
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP V + FQ K + L +A+NG+LL ++ + G+ E +R + +I+S L+Y+H
Sbjct: 112 HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHG 171
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK EN+L+ + ++ITDFG A+ + + + ++ G+ Y +PE+L
Sbjct: 172 KGIIHRDLKPENILLNEDMYIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 231
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRF 247
K +D+W++G I+Y ++ PF + +++K + ++ F
Sbjct: 232 AC-KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDF 274
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 130 bits (314), Expect = 7e-30
Identities = 86/277 (31%), Positives = 146/277 (52%), Gaps = 17/277 (6%)
Query: 16 IAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRE 75
IA EK + +VIG+G++A V + H ETR + A K+ID ++ + E
Sbjct: 308 IAANVEKHYETGRVIGDGNFAVVKECRHR--ETRQAY-AMKIIDKSRLKGK--EDMVDSE 362
Query: 76 LDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQII 135
+ ++ ++HP+IV + +++ + ++ L + + GDL D + ++ PE + L + +
Sbjct: 363 ILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLC 422
Query: 136 SGLQYIHTMNIAHRDLKCENVLVTANYN----VKITDFGFARNVRQRDRDVLSETYCGSL 191
L ++H +I HRDLK EN+LV N + +K+ DFG A++V R + T CG+
Sbjct: 423 KALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHV---VRPIF--TVCGTP 477
Query: 192 SYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFN--ETSVKKLYEKQVMRKWRFRT 249
+Y APE+L Y ++ DMW+ GVILY +L PF E +L+ + + F
Sbjct: 478 TYVAPEILSEKGYGLEV-DMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLP 536
Query: 250 TVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+ +S K+ V++L+ +PK R TA V WI
Sbjct: 537 PYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWI 573
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 130 bits (313), Expect = 1e-29
Identities = 70/206 (33%), Positives = 112/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GSY KV+ + + A KV+ A RD + + R D+L +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMER--DILAEV 116
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++KITDFG ++ D+ S +CG++ Y APEV+
Sbjct: 177 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYS--FCGTIEYMAPEVVNRR 234
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML +LPF
Sbjct: 235 GH-TQSADWWSFGVLMFEMLTGSLPF 259
Score = 111 bits (266), Expect = 5e-24
Identities = 72/272 (26%), Positives = 139/272 (51%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H +T +++ K+ID +K RD E+++L+R
Sbjct: 414 GYEIKEDIGVGSYSVCKRCVHKATDTEYAV---KIIDKSK--RDP-----SEEIEILLRY 463
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I + Y+
Sbjct: 464 GQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYL 523
Query: 142 HTMNIAHRDLKCENVLVT----ANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H+ + HRDLK N+L + ++++ DFGFA+ +R + L T C + ++ APE
Sbjct: 524 HSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNG--LLMTPCYTANFVAPE 581
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+G++LYTML PF + + +++ + K+ +
Sbjct: 582 VLKRQGY-DAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDS 640
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA V W+
Sbjct: 641 ISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWV 672
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 130 bits (313), Expect = 1e-29
Identities = 70/206 (33%), Positives = 112/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GSY KV+ + + A KV+ A RD + + R D+L +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMER--DILAEV 116
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++KITDFG ++ D+ S +CG++ Y APEV+
Sbjct: 177 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYS--FCGTIEYMAPEVVNRR 234
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML +LPF
Sbjct: 235 GH-TQSADWWSFGVLMFEMLTGSLPF 259
Score = 111 bits (266), Expect = 5e-24
Identities = 72/272 (26%), Positives = 139/272 (51%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H +T +++ K+ID +K RD E+++L+R
Sbjct: 414 GYEIKEDIGVGSYSVCKRCVHKATDTEYAV---KIIDKSK--RDP-----SEEIEILLRY 463
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I + Y+
Sbjct: 464 GQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYL 523
Query: 142 HTMNIAHRDLKCENVLVT----ANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H+ + HRDLK N+L + ++++ DFGFA+ +R + L T C + ++ APE
Sbjct: 524 HSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNG--LLMTPCYTANFVAPE 581
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+G++LYTML PF + + +++ + K+ +
Sbjct: 582 VLKRQGY-DAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDS 640
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA V W+
Sbjct: 641 ISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWV 672
>BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 130 bits (313), Expect = 1e-29
Identities = 79/264 (29%), Positives = 136/264 (51%), Gaps = 11/264 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
++ +IG GS+++V + +T A KV++T + + EL VL R++H
Sbjct: 65 IKALIGTGSFSRVVRVEQ---KTTKKPFAIKVMETREREG---REACVSELSVLRRVSHR 118
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + IF+ + ++ + A G+L D L G+ E + ++ + G++Y+H +
Sbjct: 119 YIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQ 178
Query: 146 IAHRDLKCENVLV---TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
I HR+LK EN+L + ITDFG A + ++ D +T CG+ Y APEVL
Sbjct: 179 ITHRNLKPENLLYYHPGEESKILITDFGLAYS-GKKSGDWTMKTLCGTPEYIAPEVLLRK 237
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262
PY DMW++GVI Y +L+ LPF++ S +LY K + K+ + +S K+
Sbjct: 238 PY-TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDF 296
Query: 263 VTQLMEPEPKSRPTASAVFNGTWI 286
+ +L+ E R +A + W+
Sbjct: 297 IDKLLILEAGHRMSAGQALDHPWV 320
>BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 130 bits (313), Expect = 1e-29
Identities = 79/264 (29%), Positives = 136/264 (51%), Gaps = 11/264 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
++ +IG GS+++V + +T A KV++T + + EL VL R++H
Sbjct: 65 IKALIGTGSFSRVVRVEQ---KTTKKPFAIKVMETREREG---REACVSELSVLRRVSHR 118
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + IF+ + ++ + A G+L D L G+ E + ++ + G++Y+H +
Sbjct: 119 YIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQ 178
Query: 146 IAHRDLKCENVLV---TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
I HR+LK EN+L + ITDFG A + ++ D +T CG+ Y APEVL
Sbjct: 179 ITHRNLKPENLLYYHPGEESKILITDFGLAYS-GKKSGDWTMKTLCGTPEYIAPEVLLRK 237
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262
PY DMW++GVI Y +L+ LPF++ S +LY K + K+ + +S K+
Sbjct: 238 PY-TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDF 296
Query: 263 VTQLMEPEPKSRPTASAVFNGTWI 286
+ +L+ E R +A + W+
Sbjct: 297 IDKLLILEAGHRMSAGQALDHPWV 320
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 130 bits (313), Expect = 1e-29
Identities = 80/269 (29%), Positives = 144/269 (53%), Gaps = 13/269 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + ++G+GS+A VY+A + +A K+ID + + + + E+ + ++
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLE---VAIKMIDKKAMYKAGMVQRVQNEVKIHCQLK 68
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIP--ENQSRLWMRQIISGLQYI 141
HP I+ + N F+ ++ L NG++ +L +N P EN++R +M QII+G+ Y+
Sbjct: 69 HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYL-KNRVKPFSENEARHFMHQIITGMLYL 127
Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKG 201
H+ I HRDL N+L+T N N+KI DFG A ++ T CG+ +Y +PE+
Sbjct: 128 HSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEK--HYTLCGTPNYISPEIATR 185
Query: 202 VPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKE 261
+ + +D+WS+G + YT+L PF+ +VK K V+ + + + LS E K+
Sbjct: 186 SAHGLE-SDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYE----MPSFLSIEAKD 240
Query: 262 QVTQLMEPEPKSRPTASAVFNGTWIGMDS 290
+ QL+ P R + S+V + ++ +S
Sbjct: 241 LIHQLLRRNPADRLSLSSVLDHPFMSRNS 269
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 130 bits (313), Expect = 1e-29
Identities = 70/206 (33%), Positives = 112/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GSY KV+ + + A KV+ A RD + + R D+L +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMER--DILAEV 116
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++KITDFG ++ D+ S +CG++ Y APEV+
Sbjct: 177 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYS--FCGTIEYMAPEVVNRR 234
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML +LPF
Sbjct: 235 GH-TQSADWWSFGVLMFEMLTGSLPF 259
Score = 111 bits (266), Expect = 5e-24
Identities = 72/272 (26%), Positives = 139/272 (51%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H +T +++ K+ID +K RD E+++L+R
Sbjct: 414 GYEIKEDIGVGSYSVCKRCVHKATDTEYAV---KIIDKSK--RDP-----SEEIEILLRY 463
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I + Y+
Sbjct: 464 GQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYL 523
Query: 142 HTMNIAHRDLKCENVLVT----ANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H+ + HRDLK N+L + ++++ DFGFA+ +R + L T C + ++ APE
Sbjct: 524 HSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNG--LLMTPCYTANFVAPE 581
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+G++LYTML PF + + +++ + K+ +
Sbjct: 582 VLKRQGY-DAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDS 640
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA V W+
Sbjct: 641 ISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWV 672
>AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase
PSKH2 protein.
Length = 385
Score = 130 bits (313), Expect = 1e-29
Identities = 79/264 (29%), Positives = 136/264 (51%), Gaps = 11/264 (4%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
++ +IG GS+++V + +T A KV++T + + EL VL R++H
Sbjct: 65 IKALIGTGSFSRVVRVEQ---KTTKKPFAIKVMETREREG---REACVSELSVLRRVSHR 118
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + IF+ + ++ + A G+L D L G+ E + ++ + G++Y+H +
Sbjct: 119 YIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQ 178
Query: 146 IAHRDLKCENVLV---TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
I HR+LK EN+L + ITDFG A + ++ D +T CG+ Y APEVL
Sbjct: 179 ITHRNLKPENLLYYHPGEESKILITDFGLAYS-GKKSGDWTMKTLCGTPEYIAPEVLLRK 237
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262
PY DMW++GVI Y +L+ LPF++ S +LY K + K+ + +S K+
Sbjct: 238 PY-TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDF 296
Query: 263 VTQLMEPEPKSRPTASAVFNGTWI 286
+ +L+ E R +A + W+
Sbjct: 297 IDKLLILEAGHRMSAGQALDHPWV 320
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 130 bits (313), Expect = 1e-29
Identities = 70/206 (33%), Positives = 112/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GSY KV+ + + A KV+ A RD + + R D+L +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMER--DILAEV 116
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 117 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 176
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++KITDFG ++ D+ S +CG++ Y APEV+
Sbjct: 177 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYS--FCGTIEYMAPEVVNRR 234
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML +LPF
Sbjct: 235 GH-TQSADWWSFGVLMFEMLTGSLPF 259
Score = 111 bits (266), Expect = 5e-24
Identities = 72/272 (26%), Positives = 139/272 (51%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H +T +++ K+ID +K RD E+++L+R
Sbjct: 414 GYEIKEDIGVGSYSVCKRCVHKATDTEYAV---KIIDKSK--RDP-----SEEIEILLRY 463
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I + Y+
Sbjct: 464 GQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYL 523
Query: 142 HTMNIAHRDLKCENVLVT----ANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H+ + HRDLK N+L + ++++ DFGFA+ +R + L T C + ++ APE
Sbjct: 524 HSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNG--LLMTPCYTANFVAPE 581
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+G++LYTML PF + + +++ + K+ +
Sbjct: 582 VLKRQGY-DAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDS 640
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA V W+
Sbjct: 641 ISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWV 672
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 130 bits (313), Expect = 1e-29
Identities = 64/224 (28%), Positives = 125/224 (55%), Gaps = 4/224 (1%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F K++GEGS++ V A + ++I K+++ ++ ++ RE DV+ R++
Sbjct: 82 FKFGKILGEGSFSTVVLARELATSREYAI---KILEKRHIIKENKVPYVTRERDVMSRLD 138
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP V + FQ K + L +A+NG+LL ++ + G+ E +R + +I+S +Y+H
Sbjct: 139 HPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSASEYLHG 198
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
I HRDLK EN+L+ + +++ITDFG A+ + + + ++ G+ Y +PE+L
Sbjct: 199 KGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKS 258
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRF 247
K +D+W++G I+Y ++ PF + +++K + ++ F
Sbjct: 259 AC-KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDF 301
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 130 bits (313), Expect = 1e-29
Identities = 70/206 (33%), Positives = 112/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GSY KV+ + + A KV+ A RD + + R D+L +
Sbjct: 132 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMER--DILAEV 189
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 190 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 249
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++KITDFG ++ D+ S +CG++ Y APEV+
Sbjct: 250 SLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYS--FCGTIEYMAPEVVNRR 307
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML +LPF
Sbjct: 308 GH-TQSADWWSFGVLMFEMLTGSLPF 332
Score = 111 bits (266), Expect = 5e-24
Identities = 72/272 (26%), Positives = 139/272 (51%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H +T +++ K+ID +K RD E+++L+R
Sbjct: 487 GYEIKEDIGVGSYSVCKRCVHKATDTEYAV---KIIDKSK--RDP-----SEEIEILLRY 536
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I + Y+
Sbjct: 537 GQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYL 596
Query: 142 HTMNIAHRDLKCENVLVT----ANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H+ + HRDLK N+L + ++++ DFGFA+ +R + L T C + ++ APE
Sbjct: 597 HSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNG--LLMTPCYTANFVAPE 654
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+G++LYTML PF + + +++ + K+ +
Sbjct: 655 VLKRQGY-DAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDS 713
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA V W+
Sbjct: 714 ISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWV 745
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 128 bits (309), Expect = 3e-29
Identities = 76/238 (31%), Positives = 128/238 (53%), Gaps = 13/238 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L+K +G G +A V A H+ + +A KVID K T L +E+ + + HP
Sbjct: 18 LDKTLGRGHFAVVKLARHVFTGEK---VAVKVIDKTKLDT-LATGHLFQEVRCMKLVQHP 73
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNG-AIPENQSRLWMRQIISGLQYIHTM 144
+IV + + + K ++ L + GD+ D++ ++ + E+ ++ + QI+ + Y H +
Sbjct: 74 NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133
Query: 145 NIAHRDLKCENVLVTANYN-VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
++ HRDLK ENV+ VK+TDFGF+ + + T CGSL+Y+APE+L G
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDE 190
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKE 261
Y D+WS+GVIL+ ++ + PF E + + + K+ TV + +S ECKE
Sbjct: 191 YDAPAVDIWSLGVILFMLVCEQPPFQEANDSETLTMIMDCKY----TVPSHVSKECKE 244
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 128 bits (308), Expect = 4e-29
Identities = 67/206 (32%), Positives = 114/206 (55%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ ++ + A KV+ A RD + + R D+L+ +
Sbjct: 68 FELLKVLGQGSFGKVFLVKKILGSDARQLYAMKVLKKATLKVRDRVRTKMER--DILVEV 125
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ D + + ++CG++ Y APEV+
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSK--ESIDHEKKAYSFCGTVEYMAPEVVNRR 243
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 244 GH-TQSADWWSFGVLMFEMLTGTLPF 268
Score = 113 bits (271), Expect = 1e-24
Identities = 77/272 (28%), Positives = 138/272 (50%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H ++ K+ID +K RD E+++L+R
Sbjct: 421 GYEVKEDIGVGSYSVCKRCIHKATNMEFAV---KIIDKSK--RDPT-----EEIEILLRY 470
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I ++Y+
Sbjct: 471 GQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYL 530
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H + HRDLK N+L V + N ++I DFGFA+ +R + L T C + ++ APE
Sbjct: 531 HAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG--LLMTPCYTANFVAPE 588
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+GV+LYTML PF + + +++ + K+ N
Sbjct: 589 VLKRQGY-DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNS 647
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA+ V WI
Sbjct: 648 VSDTAKDLVSKMLHVDPHQRLTAALVLRHPWI 679
>BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 128 bits (308), Expect = 4e-29
Identities = 74/277 (26%), Positives = 142/277 (51%), Gaps = 10/277 (3%)
Query: 1 MGGGDKIDLSTTQSDIAV--LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVI 58
+G ++++L+ T ++ + F L +V+G+G Y KV++ + I A KV+
Sbjct: 42 VGHYEEVELTETSVNVGPERIGPHSFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVL 101
Query: 59 DTAKAPRDYL-TKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLT 117
AK R+ T E ++L + HP IV ++ FQ K ++ L G+L L
Sbjct: 102 RKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLE 161
Query: 118 QNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQ 177
+ G E+ + ++ +I L ++H+ I +RDLK EN+++++ ++K+TDFG +
Sbjct: 162 REGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCK--ES 219
Query: 178 RDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237
++ T+CG++ Y APE+L + + D WS+G ++Y ML + PF + KK
Sbjct: 220 IHEGAVTHTFCGTIEYMAPEILVRSGH-NRAVDWWSLGALMYDMLTGSPPFTAENRKKTM 278
Query: 238 EKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSR 274
+K + R + + L+ + ++ V + ++ P R
Sbjct: 279 DKII----RGKLALPPYLTPDARDLVKKFLKRNPSQR 311
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 127 bits (307), Expect = 5e-29
Identities = 74/268 (27%), Positives = 138/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A ++ H I+A KV+ ++ ++ + L RE+++ ++
Sbjct: 77 FEIGRPLGKGKFGNVYLAR---EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F R + ++ L +A G+L L ++ E ++ M ++ L Y H
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ +KI DFG++ + R +T CG+L Y PE+++G
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRM 249
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
+ K+ D+W IGV+ Y +L PF S + Y + V +F +V T ++ +
Sbjct: 250 HNEKV-DLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASV----PTGAQDLI 304
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ P R + V W+ +SR
Sbjct: 305 SKLLRHNPSERLPLAQVSAHPWVRANSR 332
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 127 bits (307), Expect = 5e-29
Identities = 74/268 (27%), Positives = 138/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A ++ H I+A KV+ ++ ++ + L RE+++ ++
Sbjct: 77 FEIGRPLGKGKFGNVYLAR---EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F R + ++ L +A G+L L ++ E ++ M ++ L Y H
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ +KI DFG++ + R +T CG+L Y PE+++G
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRM 249
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
+ K+ D+W IGV+ Y +L PF S + Y + V +F +V T ++ +
Sbjct: 250 HNEKV-DLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASV----PTGAQDLI 304
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ P R + V W+ +SR
Sbjct: 305 SKLLRHNPSERLPLAQVSAHPWVRANSR 332
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 127 bits (307), Expect = 5e-29
Identities = 74/268 (27%), Positives = 138/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A ++ H I+A KV+ ++ ++ + L RE+++ ++
Sbjct: 77 FEIGRPLGKGKFGNVYLAR---EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F R + ++ L +A G+L L ++ E ++ M ++ L Y H
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ +KI DFG++ + R +T CG+L Y PE+++G
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRM 249
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
+ K+ D+W IGV+ Y +L PF S + Y + V +F +V T ++ +
Sbjct: 250 HNEKV-DLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASV----PTGAQDLI 304
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ P R + V W+ +SR
Sbjct: 305 SKLLRHNPSERLPLAQVSAHPWVRANSR 332
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 127 bits (307), Expect = 5e-29
Identities = 74/268 (27%), Positives = 138/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A ++ H I+A KV+ ++ ++ + L RE+++ ++
Sbjct: 77 FEIGRPLGKGKFGNVYLAR---EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F R + ++ L +A G+L L ++ E ++ M ++ L Y H
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ +KI DFG++ + R +T CG+L Y PE+++G
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRM 249
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
+ K+ D+W IGV+ Y +L PF S + Y + V +F +V T ++ +
Sbjct: 250 HNEKV-DLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASV----PTGAQDLI 304
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ P R + V W+ +SR
Sbjct: 305 SKLLRHNPSERLPLAQVSAHPWVRANSR 332
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 127 bits (307), Expect = 5e-29
Identities = 74/268 (27%), Positives = 138/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A ++ H I+A KV+ ++ ++ + L RE+++ ++
Sbjct: 77 FEIGRPLGKGKFGNVYLAR---EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F R + ++ L +A G+L L ++ E ++ M ++ L Y H
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ +KI DFG++ + R +T CG+L Y PE+++G
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRM 249
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
+ K+ D+W IGV+ Y +L PF S + Y + V +F +V T ++ +
Sbjct: 250 HNEKV-DLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASV----PTGAQDLI 304
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ P R + V W+ +SR
Sbjct: 305 SKLLRHNPSERLPLAQVSAHPWVRANSR 332
>X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase
protein.
Length = 387
Score = 127 bits (306), Expect = 7e-29
Identities = 74/260 (28%), Positives = 139/260 (53%), Gaps = 12/260 (4%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDY--LTKFLPRELDVLIRIN 83
++++G G + V + H +++ V +P + L + +E+D+L +++
Sbjct: 23 KEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVS 82
Query: 84 -HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
HP+I+ + + ++ +F+ + G+L D+LT+ + E ++R MR ++ + +H
Sbjct: 83 GHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLH 142
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL--- 199
+NI HRDLK EN+L+ N N+K+TDFGF+ + +R L E CG+ SY APE++
Sbjct: 143 KLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER--LREV-CGTPSYLAPEIIECS 199
Query: 200 --KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
+ P K DMWS GVI+YT+L + PF + + ++F + + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 258 ECKEQVTQLMEPEPKSRPTA 277
K+ V++ + +P++R TA
Sbjct: 260 TVKDLVSRFLVVQPQNRYTA 279
>L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin dependent
protein kinase protein.
Length = 473
Score = 127 bits (306), Expect = 7e-29
Identities = 77/267 (28%), Positives = 137/267 (51%), Gaps = 16/267 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F +E +G G+ + VY+ + +++ K K R E+ VL+R++
Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRT--------EIGVLLRLS 97
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + IF+ + + L G+L D + + G E + ++QI+ + Y+H
Sbjct: 98 HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHE 157
Query: 144 MNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200
I HRDLK EN+L + +KI DFG ++ V + VL +T CG+ Y APE+L+
Sbjct: 158 NGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIV---EHQVLMKTVCGTPGYCAPEILR 214
Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKKLYEKQVMRKWRFRTTVVNQLSTEC 259
G Y P++ DMWS+G+I Y +L PF +E + ++ + + ++ F + +++S
Sbjct: 215 GCAYGPEV-DMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNA 273
Query: 260 KEQVTQLMEPEPKSRPTASAVFNGTWI 286
K+ V +L+ +PK R T W+
Sbjct: 274 KDLVRKLIVLDPKKRLTTFQALQHPWV 300
>L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-dependent
protein kinase protein.
Length = 473
Score = 127 bits (306), Expect = 7e-29
Identities = 77/267 (28%), Positives = 137/267 (51%), Gaps = 16/267 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F +E +G G+ + VY+ + +++ K K R E+ VL+R++
Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRT--------EIGVLLRLS 97
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + IF+ + + L G+L D + + G E + ++QI+ + Y+H
Sbjct: 98 HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHE 157
Query: 144 MNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200
I HRDLK EN+L + +KI DFG ++ V + VL +T CG+ Y APE+L+
Sbjct: 158 NGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIV---EHQVLMKTVCGTPGYCAPEILR 214
Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKKLYEKQVMRKWRFRTTVVNQLSTEC 259
G Y P++ DMWS+G+I Y +L PF +E + ++ + + ++ F + +++S
Sbjct: 215 GCAYGPEV-DMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNA 273
Query: 260 KEQVTQLMEPEPKSRPTASAVFNGTWI 286
K+ V +L+ +PK R T W+
Sbjct: 274 KDLVRKLIVLDPKKRLTTFQALQHPWV 300
>L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kinase
1 protein.
Length = 735
Score = 127 bits (306), Expect = 7e-29
Identities = 76/252 (30%), Positives = 128/252 (50%), Gaps = 10/252 (3%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + + A KV+ A RD + + R D+L +
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMER--DILADV 119
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP +V + FQ K ++ L F GDL L++ E + ++ ++ GL ++H
Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ ++ S +CG++ Y APEV+
Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQ 237
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262
+ AD WS GV+++ ML +LPF K+ + K + LSTE +
Sbjct: 238 GHSHS-ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAK----LGMPQFLSTEAQSL 292
Query: 263 VTQLMEPEPKSR 274
+ L + P +R
Sbjct: 293 LRALFKRNPANR 304
Score = 119 bits (287), Expect = 1e-26
Identities = 84/314 (26%), Positives = 160/314 (50%), Gaps = 23/314 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+++++ IG GSY++ + H +++ KVID +K RD E+++L+R
Sbjct: 417 GYVVKETIGVGSYSECKRCVHKATNMEYAV---KVIDKSK--RDP-----SEEIEILLRY 466
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ G+LLD + + E ++ + I ++Y+
Sbjct: 467 GQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYL 526
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H+ + HRDLK N+L V + N ++I DFGFA+ +R + L T C + ++ APE
Sbjct: 527 HSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENG--LLMTPCYTANFVAPE 584
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y + D+WS+G++LYTML PF + +++ + K+ N
Sbjct: 585 VLKRQGY-DEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNT 643
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRL--AKLTFLEESLLKQAHEESQK 312
+S K+ V++++ +P R TA V W+ +L ++L+ + L+K A +
Sbjct: 644 VSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQLSHQDLQLVKGAMAATYS 703
Query: 313 RDNSTEEDSEVERI 326
NS++ +++ I
Sbjct: 704 ALNSSKPTPQLKPI 717
>D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent protein
kinase IV protein.
Length = 473
Score = 127 bits (306), Expect = 7e-29
Identities = 77/267 (28%), Positives = 137/267 (51%), Gaps = 16/267 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F +E +G G+ + VY+ + +++ K K R E+ VL+R++
Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRT--------EIGVLLRLS 97
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + IF+ + + L G+L D + + G E + ++QI+ + Y+H
Sbjct: 98 HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHE 157
Query: 144 MNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200
I HRDLK EN+L + +KI DFG ++ V + VL +T CG+ Y APE+L+
Sbjct: 158 NGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIV---EHQVLMKTVCGTPGYCAPEILR 214
Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKKLYEKQVMRKWRFRTTVVNQLSTEC 259
G Y P++ DMWS+G+I Y +L PF +E + ++ + + ++ F + +++S
Sbjct: 215 GCAYGPEV-DMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNA 273
Query: 260 KEQVTQLMEPEPKSRPTASAVFNGTWI 286
K+ V +L+ +PK R T W+
Sbjct: 274 KDLVRKLIVLDPKKRLTTFQALQHPWV 300
>BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 127 bits (306), Expect = 7e-29
Identities = 74/260 (28%), Positives = 139/260 (53%), Gaps = 12/260 (4%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDY--LTKFLPRELDVLIRIN 83
++++G G + V + H +++ V +P + L + +E+D+L +++
Sbjct: 23 KEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVS 82
Query: 84 -HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
HP+I+ + + ++ +F+ + G+L D+LT+ + E ++R MR ++ + +H
Sbjct: 83 GHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLH 142
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL--- 199
+NI HRDLK EN+L+ N N+K+TDFGF+ + +R L E CG+ SY APE++
Sbjct: 143 KLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER--LREV-CGTPSYLAPEIIECS 199
Query: 200 --KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
+ P K DMWS GVI+YT+L + PF + + ++F + + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 258 ECKEQVTQLMEPEPKSRPTA 277
K+ V++ + +P++R TA
Sbjct: 260 TVKDLVSRFLVVQPQNRYTA 279
>BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 127 bits (306), Expect = 7e-29
Identities = 74/260 (28%), Positives = 139/260 (53%), Gaps = 12/260 (4%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDY--LTKFLPRELDVLIRIN 83
++++G G + V + H +++ V +P + L + +E+D+L +++
Sbjct: 23 KEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVS 82
Query: 84 -HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
HP+I+ + + ++ +F+ + G+L D+LT+ + E ++R MR ++ + +H
Sbjct: 83 GHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLH 142
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL--- 199
+NI HRDLK EN+L+ N N+K+TDFGF+ + +R L E CG+ SY APE++
Sbjct: 143 KLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER--LREV-CGTPSYLAPEIIECS 199
Query: 200 --KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
+ P K DMWS GVI+YT+L + PF + + ++F + + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 258 ECKEQVTQLMEPEPKSRPTA 277
K+ V++ + +P++R TA
Sbjct: 260 TVKDLVSRFLVVQPQNRYTA 279
>BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 127 bits (306), Expect = 7e-29
Identities = 74/260 (28%), Positives = 139/260 (53%), Gaps = 12/260 (4%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDY--LTKFLPRELDVLIRIN 83
++++G G + V + H +++ V +P + L + +E+D+L +++
Sbjct: 23 KEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVS 82
Query: 84 -HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
HP+I+ + + ++ +F+ + G+L D+LT+ + E ++R MR ++ + +H
Sbjct: 83 GHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLH 142
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL--- 199
+NI HRDLK EN+L+ N N+K+TDFGF+ + +R L E CG+ SY APE++
Sbjct: 143 KLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER--LREV-CGTPSYLAPEIIECS 199
Query: 200 --KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
+ P K DMWS GVI+YT+L + PF + + ++F + + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 258 ECKEQVTQLMEPEPKSRPTA 277
K+ V++ + +P++R TA
Sbjct: 260 TVKDLVSRFLVVQPQNRYTA 279
>BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 127 bits (306), Expect = 7e-29
Identities = 74/260 (28%), Positives = 139/260 (53%), Gaps = 12/260 (4%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDY--LTKFLPRELDVLIRIN 83
++++G G + V + H +++ V +P + L + +E+D+L +++
Sbjct: 23 KEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVS 82
Query: 84 -HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
HP+I+ + + ++ +F+ + G+L D+LT+ + E ++R MR ++ + +H
Sbjct: 83 GHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLH 142
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL--- 199
+NI HRDLK EN+L+ N N+K+TDFGF+ + +R L E CG+ SY APE++
Sbjct: 143 KLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER--LREV-CGTPSYLAPEIIECS 199
Query: 200 --KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
+ P K DMWS GVI+YT+L + PF + + ++F + + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 258 ECKEQVTQLMEPEPKSRPTA 277
K+ V++ + +P++R TA
Sbjct: 260 TVKDLVSRFLVVQPQNRYTA 279
>BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase,
gamma 1 (muscle) protein.
Length = 387
Score = 127 bits (306), Expect = 7e-29
Identities = 74/260 (28%), Positives = 139/260 (53%), Gaps = 12/260 (4%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDY--LTKFLPRELDVLIRIN 83
++++G G + V + H +++ V +P + L + +E+D+L +++
Sbjct: 23 KEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVS 82
Query: 84 -HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
HP+I+ + + ++ +F+ + G+L D+LT+ + E ++R MR ++ + +H
Sbjct: 83 GHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLH 142
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL--- 199
+NI HRDLK EN+L+ N N+K+TDFGF+ + +R L E CG+ SY APE++
Sbjct: 143 KLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER--LREV-CGTPSYLAPEIIECS 199
Query: 200 --KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
+ P K DMWS GVI+YT+L + PF + + ++F + + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 258 ECKEQVTQLMEPEPKSRPTA 277
K+ V++ + +P++R TA
Sbjct: 260 TVKDLVSRFLVVQPQNRYTA 279
>BC025687-1|AAH25687.1| 473|Homo sapiens
calcium/calmodulin-dependent protein kinase IV protein.
Length = 473
Score = 127 bits (306), Expect = 7e-29
Identities = 77/267 (28%), Positives = 137/267 (51%), Gaps = 16/267 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F +E +G G+ + VY+ + +++ K K R E+ VL+R++
Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRT--------EIGVLLRLS 97
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + IF+ + + L G+L D + + G E + ++QI+ + Y+H
Sbjct: 98 HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHE 157
Query: 144 MNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200
I HRDLK EN+L + +KI DFG ++ V + VL +T CG+ Y APE+L+
Sbjct: 158 NGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIV---EHQVLMKTVCGTPGYCAPEILR 214
Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKKLYEKQVMRKWRFRTTVVNQLSTEC 259
G Y P++ DMWS+G+I Y +L PF +E + ++ + + ++ F + +++S
Sbjct: 215 GCAYGPEV-DMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNA 273
Query: 260 KEQVTQLMEPEPKSRPTASAVFNGTWI 286
K+ V +L+ +PK R T W+
Sbjct: 274 KDLVRKLIVLDPKKRLTTFQALQHPWV 300
>BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein.
Length = 503
Score = 127 bits (306), Expect = 7e-29
Identities = 77/267 (28%), Positives = 137/267 (51%), Gaps = 16/267 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F +E +G G+ + VY+ + +++ K K R E+ VL+R++
Sbjct: 76 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRT--------EIGVLLRLS 127
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + IF+ + + L G+L D + + G E + ++QI+ + Y+H
Sbjct: 128 HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHE 187
Query: 144 MNIAHRDLKCENVLVTA---NYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200
I HRDLK EN+L + +KI DFG ++ V + VL +T CG+ Y APE+L+
Sbjct: 188 NGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIV---EHQVLMKTVCGTPGYCAPEILR 244
Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKKLYEKQVMRKWRFRTTVVNQLSTEC 259
G Y P++ DMWS+G+I Y +L PF +E + ++ + + ++ F + +++S
Sbjct: 245 GCAYGPEV-DMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNA 303
Query: 260 KEQVTQLMEPEPKSRPTASAVFNGTWI 286
K+ V +L+ +PK R T W+
Sbjct: 304 KDLVRKLIVLDPKKRLTTFQALQHPWV 330
>BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 127 bits (306), Expect = 7e-29
Identities = 76/252 (30%), Positives = 128/252 (50%), Gaps = 10/252 (3%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + + A KV+ A RD + + R D+L +
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMER--DILADV 119
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP +V + FQ K ++ L F GDL L++ E + ++ ++ GL ++H
Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ ++ S +CG++ Y APEV+
Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQ 237
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262
+ AD WS GV+++ ML +LPF K+ + K + LSTE +
Sbjct: 238 GHSHS-ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAK----LGMPQFLSTEAQSL 292
Query: 263 VTQLMEPEPKSR 274
+ L + P +R
Sbjct: 293 LRALFKRNPANR 304
Score = 119 bits (287), Expect = 1e-26
Identities = 84/314 (26%), Positives = 160/314 (50%), Gaps = 23/314 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+++++ IG GSY++ + H +++ KVID +K RD E+++L+R
Sbjct: 417 GYVVKETIGVGSYSECKRCVHKATNMEYAV---KVIDKSK--RDP-----SEEIEILLRY 466
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ G+LLD + + E ++ + I ++Y+
Sbjct: 467 GQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYL 526
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H+ + HRDLK N+L V + N ++I DFGFA+ +R + L T C + ++ APE
Sbjct: 527 HSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENG--LLMTPCYTANFVAPE 584
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y + D+WS+G++LYTML PF + +++ + K+ N
Sbjct: 585 VLKRQGY-DEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNT 643
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRL--AKLTFLEESLLKQAHEESQK 312
+S K+ V++++ +P R TA V W+ +L ++L+ + L+K A +
Sbjct: 644 VSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQLSHQDLQLVKGAMAATYS 703
Query: 313 RDNSTEEDSEVERI 326
NS++ +++ I
Sbjct: 704 ALNSSKPTPQLKPI 717
>AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 127 bits (306), Expect = 7e-29
Identities = 76/252 (30%), Positives = 128/252 (50%), Gaps = 10/252 (3%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + + A KV+ A RD + + R D+L +
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMER--DILADV 119
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP +V + FQ K ++ L F GDL L++ E + ++ ++ GL ++H
Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ ++ S +CG++ Y APEV+
Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYS--FCGTVEYMAPEVVNRQ 237
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQ 262
+ AD WS GV+++ ML +LPF K+ + K + LSTE +
Sbjct: 238 GHSHS-ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAK----LGMPQFLSTEAQSL 292
Query: 263 VTQLMEPEPKSR 274
+ L + P +R
Sbjct: 293 LRALFKRNPANR 304
Score = 119 bits (287), Expect = 1e-26
Identities = 84/314 (26%), Positives = 160/314 (50%), Gaps = 23/314 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+++++ IG GSY++ + H +++ KVID +K RD E+++L+R
Sbjct: 417 GYVVKETIGVGSYSECKRCVHKATNMEYAV---KVIDKSK--RDP-----SEEIEILLRY 466
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ G+LLD + + E ++ + I ++Y+
Sbjct: 467 GQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYL 526
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H+ + HRDLK N+L V + N ++I DFGFA+ +R + L T C + ++ APE
Sbjct: 527 HSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENG--LLMTPCYTANFVAPE 584
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y + D+WS+G++LYTML PF + +++ + K+ N
Sbjct: 585 VLKRQGY-DEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNT 643
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRL--AKLTFLEESLLKQAHEESQK 312
+S K+ V++++ +P R TA V W+ +L ++L+ + L+K A +
Sbjct: 644 VSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQLSHQDLQLVKGAMAATYS 703
Query: 313 RDNSTEEDSEVERI 326
NS++ +++ I
Sbjct: 704 ALNSSKPTPQLKPI 717
>AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase gamma
protein.
Length = 387
Score = 127 bits (306), Expect = 7e-29
Identities = 74/260 (28%), Positives = 139/260 (53%), Gaps = 12/260 (4%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDY--LTKFLPRELDVLIRIN 83
++++G G + V + H +++ V +P + L + +E+D+L +++
Sbjct: 23 KEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVS 82
Query: 84 -HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
HP+I+ + + ++ +F+ + G+L D+LT+ + E ++R MR ++ + +H
Sbjct: 83 GHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLH 142
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL--- 199
+NI HRDLK EN+L+ N N+K+TDFGF+ + +R L E CG+ SY APE++
Sbjct: 143 KLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER--LREV-CGTPSYLAPEIIECS 199
Query: 200 --KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
+ P K DMWS GVI+YT+L + PF + + ++F + + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 258 ECKEQVTQLMEPEPKSRPTA 277
K+ V++ + +P++R TA
Sbjct: 260 TVKDLVSRFLVVQPQNRYTA 279
>AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein.
Length = 387
Score = 127 bits (306), Expect = 7e-29
Identities = 74/260 (28%), Positives = 139/260 (53%), Gaps = 12/260 (4%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDY--LTKFLPRELDVLIRIN 83
++++G G + V + H +++ V +P + L + +E+D+L +++
Sbjct: 23 KEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVS 82
Query: 84 -HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
HP+I+ + + ++ +F+ + G+L D+LT+ + E ++R MR ++ + +H
Sbjct: 83 GHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLH 142
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL--- 199
+NI HRDLK EN+L+ N N+K+TDFGF+ + +R L E CG+ SY APE++
Sbjct: 143 KLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER--LREV-CGTPSYLAPEIIECS 199
Query: 200 --KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLST 257
+ P K DMWS GVI+YT+L + PF + + ++F + + S
Sbjct: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259
Query: 258 ECKEQVTQLMEPEPKSRPTA 277
K+ V++ + +P++R TA
Sbjct: 260 TVKDLVSRFLVVQPQNRYTA 279
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 126 bits (305), Expect = 9e-29
Identities = 69/227 (30%), Positives = 120/227 (52%), Gaps = 7/227 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR-INHPH 86
KVIG+GS+ KV A H +E +++ KV+ + K + E +VL++ + HP
Sbjct: 197 KVIGKGSFGKVLLARHKAEEVFYAV---KVLQKKAILKKKEEKHIMSERNVLLKNVKHPF 253
Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146
+V + FQ K + L + G+L L + E ++R + +I S L Y+H++NI
Sbjct: 254 LVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 313
Query: 147 AHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMP 206
+RDLK EN+L+ + ++ +TDFG + + + + T+CG+ Y APEVL PY
Sbjct: 314 VYRDLKPENILLDSQGHIVLTDFGLCK--ENIEHNSTTSTFCGTPEYLAPEVLHKQPY-D 370
Query: 207 KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVN 253
+ D W +G +LY ML PF + ++Y+ + + + + + N
Sbjct: 371 RTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN 417
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 126 bits (305), Expect = 9e-29
Identities = 69/227 (30%), Positives = 120/227 (52%), Gaps = 7/227 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR-INHPH 86
KVIG+GS+ KV A H +E +++ KV+ + K + E +VL++ + HP
Sbjct: 102 KVIGKGSFGKVLLARHKAEEVFYAV---KVLQKKAILKKKEEKHIMSERNVLLKNVKHPF 158
Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146
+V + FQ K + L + G+L L + E ++R + +I S L Y+H++NI
Sbjct: 159 LVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 218
Query: 147 AHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMP 206
+RDLK EN+L+ + ++ +TDFG + + + + T+CG+ Y APEVL PY
Sbjct: 219 VYRDLKPENILLDSQGHIVLTDFGLCK--ENIEHNSTTSTFCGTPEYLAPEVLHKQPY-D 275
Query: 207 KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVN 253
+ D W +G +LY ML PF + ++Y+ + + + + + N
Sbjct: 276 RTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN 322
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 126 bits (305), Expect = 9e-29
Identities = 67/206 (32%), Positives = 113/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + + A KV+ A RD + + R D+L+ +
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER--DILVEV 125
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ D + + ++CG++ Y APEV+
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSK--ESIDHEKKAYSFCGTVEYMAPEVVNRR 243
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 244 GH-TQSADWWSFGVLMFEMLTGTLPF 268
Score = 113 bits (271), Expect = 1e-24
Identities = 77/272 (28%), Positives = 138/272 (50%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H ++ K+ID +K RD E+++L+R
Sbjct: 421 GYEVKEDIGVGSYSVCKRCIHKATNMEFAV---KIIDKSK--RDPT-----EEIEILLRY 470
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I ++Y+
Sbjct: 471 GQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYL 530
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H + HRDLK N+L V + N ++I DFGFA+ +R + L T C + ++ APE
Sbjct: 531 HAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG--LLMTPCYTANFVAPE 588
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+GV+LYTML PF + + +++ + K+ N
Sbjct: 589 VLKRQGY-DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNS 647
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA+ V WI
Sbjct: 648 VSDTAKDLVSKMLHVDPHQRLTAALVLRHPWI 679
>L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kinase
3 protein.
Length = 580
Score = 126 bits (305), Expect = 9e-29
Identities = 67/206 (32%), Positives = 113/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + + A KV+ A RD + + R D+L+ +
Sbjct: 67 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER--DILVEV 124
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 125 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 184
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ D + + ++CG++ Y APEV+
Sbjct: 185 SLGIIYRDLKPENILLDEEGHIKLTDFGLSK--ESIDHEKKAYSFCGTVEYMAPEVVNRR 242
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 243 GH-TQSADWWSFGVLMFEMLTGTLPF 267
Score = 70.5 bits (165), Expect = 8e-12
Identities = 47/170 (27%), Positives = 89/170 (52%), Gaps = 16/170 (9%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ L++ IG GSY+ + H ++ K+ID +K RD E+++L+R
Sbjct: 420 GYELKEDIGVGSYSVCKRCIHKATNMEFAV---KIIDKSK--RDPT-----EEIEILLRY 469
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ +++++ KY + + G+LLD + + E ++ + I ++Y+
Sbjct: 470 GQHPNIITLNDVYDD-GKYVYVVTLMKGGELLDKILRQKFFSEREASAVLFTITKTVEYL 528
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETY 187
H + HRDLK N+L V + N ++I DFGFA+ +R + +++ Y
Sbjct: 529 HAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCY 578
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 126 bits (305), Expect = 9e-29
Identities = 67/206 (32%), Positives = 113/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + + A KV+ A RD + + R D+L+ +
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER--DILVEV 125
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ D + + ++CG++ Y APEV+
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSK--ESIDHEKKAYSFCGTVEYMAPEVVNRR 243
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 244 GH-TQSADWWSFGVLMFEMLTGTLPF 268
Score = 113 bits (271), Expect = 1e-24
Identities = 77/272 (28%), Positives = 138/272 (50%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H ++ K+ID +K RD E+++L+R
Sbjct: 421 GYEVKEDIGVGSYSVCKRCIHKATNMEFAV---KIIDKSK--RDPT-----EEIEILLRY 470
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I ++Y+
Sbjct: 471 GQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYL 530
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H + HRDLK N+L V + N ++I DFGFA+ +R + L T C + ++ APE
Sbjct: 531 HAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG--LLMTPCYTANFVAPE 588
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+GV+LYTML PF + + +++ + K+ N
Sbjct: 589 VLKRQGY-DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNS 647
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA+ V WI
Sbjct: 648 VSDTAKDLVSKMLHVDPHQRLTAALVLRHPWI 679
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 126 bits (305), Expect = 9e-29
Identities = 67/206 (32%), Positives = 113/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + + A KV+ A RD + + R D+L+ +
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER--DILVEV 125
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ D + + ++CG++ Y APEV+
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSK--ESIDHEKKAYSFCGTVEYMAPEVVNRR 243
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 244 GH-TQSADWWSFGVLMFEMLTGTLPF 268
Score = 113 bits (271), Expect = 1e-24
Identities = 77/272 (28%), Positives = 138/272 (50%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H ++ K+ID +K RD E+++L+R
Sbjct: 421 GYEVKEDIGVGSYSVCKRCIHKATNMEFAV---KIIDKSK--RDPT-----EEIEILLRY 470
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I ++Y+
Sbjct: 471 GQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYL 530
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H + HRDLK N+L V + N ++I DFGFA+ +R + L T C + ++ APE
Sbjct: 531 HAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG--LLMTPCYTANFVAPE 588
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+GV+LYTML PF + + +++ + K+ N
Sbjct: 589 VLKRQGY-DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNS 647
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA+ V WI
Sbjct: 648 VSDTAKDLVSKMLHVDPHQRLTAALVLRHPWI 679
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 126 bits (305), Expect = 9e-29
Identities = 69/227 (30%), Positives = 120/227 (52%), Gaps = 7/227 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR-INHPH 86
KVIG+GS+ KV A H +E +++ KV+ + K + E +VL++ + HP
Sbjct: 102 KVIGKGSFGKVLLARHKAEEVFYAV---KVLQKKAILKKKEEKHIMSERNVLLKNVKHPF 158
Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146
+V + FQ K + L + G+L L + E ++R + +I S L Y+H++NI
Sbjct: 159 LVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 218
Query: 147 AHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMP 206
+RDLK EN+L+ + ++ +TDFG + + + + T+CG+ Y APEVL PY
Sbjct: 219 VYRDLKPENILLDSQGHIVLTDFGLCK--ENIEHNSTTSTFCGTPEYLAPEVLHKQPY-D 275
Query: 207 KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVN 253
+ D W +G +LY ML PF + ++Y+ + + + + + N
Sbjct: 276 RTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN 322
>BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 126 bits (305), Expect = 9e-29
Identities = 74/277 (26%), Positives = 142/277 (51%), Gaps = 10/277 (3%)
Query: 1 MGGGDKIDLSTTQSDIAV--LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVI 58
+G ++++L+ T ++ + F L +V+G+G Y KV++ + I A KV+
Sbjct: 42 VGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVL 101
Query: 59 DTAKAPRDYL-TKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLT 117
AK R+ T E ++L + HP IV ++ FQ K ++ L G+L L
Sbjct: 102 RKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLE 161
Query: 118 QNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQ 177
+ G E+ + ++ +I L ++H+ I +RDLK EN+++++ ++K+TDFG +
Sbjct: 162 REGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCK--ES 219
Query: 178 RDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237
++ T+CG++ Y APE+L + + D WS+G ++Y ML + PF + KK
Sbjct: 220 IHEGAVTHTFCGTIEYMAPEILVRSGH-NRAVDWWSLGALMYDMLTGSPPFTAENRKKTM 278
Query: 238 EKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSR 274
+K + R + + L+ + ++ V + ++ P R
Sbjct: 279 DKII----RGKLALPPYLTPDARDLVKKFLKRNPSQR 311
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 126 bits (305), Expect = 9e-29
Identities = 67/206 (32%), Positives = 113/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + + A KV+ A RD + + R D+L+ +
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER--DILVEV 125
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ D + + ++CG++ Y APEV+
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSK--ESIDHEKKAYSFCGTVEYMAPEVVNRR 243
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 244 GH-TQSADWWSFGVLMFEMLTGTLPF 268
Score = 113 bits (271), Expect = 1e-24
Identities = 77/272 (28%), Positives = 138/272 (50%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H ++ K+ID +K RD E+++L+R
Sbjct: 421 GYEVKEDIGVGSYSVCKRCIHKATNMEFAV---KIIDKSK--RDPT-----EEIEILLRY 470
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I ++Y+
Sbjct: 471 GQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYL 530
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H + HRDLK N+L V + N ++I DFGFA+ +R + L T C + ++ APE
Sbjct: 531 HAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG--LLMTPCYTANFVAPE 588
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+GV+LYTML PF + + +++ + K+ N
Sbjct: 589 VLKRQGY-DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNS 647
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA+ V WI
Sbjct: 648 VSDTAKDLVSKMLHVDPHQRLTAALVLRHPWI 679
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 126 bits (305), Expect = 9e-29
Identities = 67/206 (32%), Positives = 113/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + + A KV+ A RD + + R D+L+ +
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER--DILVEV 125
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ D + + ++CG++ Y APEV+
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSK--ESIDHEKKAYSFCGTVEYMAPEVVNRR 243
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 244 GH-TQSADWWSFGVLMFEMLTGTLPF 268
Score = 113 bits (271), Expect = 1e-24
Identities = 77/272 (28%), Positives = 138/272 (50%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H ++ K+ID +K RD E+++L+R
Sbjct: 421 GYEVKEDIGVGSYSVCKRCIHKATNMEFAV---KIIDKSK--RDPT-----EEIEILLRY 470
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I ++Y+
Sbjct: 471 GQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYL 530
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H + HRDLK N+L V + N ++I DFGFA+ +R + L T C + ++ APE
Sbjct: 531 HAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG--LLMTPCYTANFVAPE 588
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+GV+LYTML PF + + +++ + K+ N
Sbjct: 589 VLKRQGY-DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNS 647
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA+ V WI
Sbjct: 648 VSDTAKDLVSKMLHVDPHQRLTAALVLRHPWI 679
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 126 bits (305), Expect = 9e-29
Identities = 69/227 (30%), Positives = 120/227 (52%), Gaps = 7/227 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR-INHPH 86
KVIG+GS+ KV A H +E +++ KV+ + K + E +VL++ + HP
Sbjct: 197 KVIGKGSFGKVLLARHKAEEVFYAV---KVLQKKAILKKKEEKHIMSERNVLLKNVKHPF 253
Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146
+V + FQ K + L + G+L L + E ++R + +I S L Y+H++NI
Sbjct: 254 LVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 313
Query: 147 AHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMP 206
+RDLK EN+L+ + ++ +TDFG + + + + T+CG+ Y APEVL PY
Sbjct: 314 VYRDLKPENILLDSQGHIVLTDFGLCK--ENIEHNSTTSTFCGTPEYLAPEVLHKQPY-D 370
Query: 207 KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVN 253
+ D W +G +LY ML PF + ++Y+ + + + + + N
Sbjct: 371 RTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN 417
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 126 bits (305), Expect = 9e-29
Identities = 69/227 (30%), Positives = 120/227 (52%), Gaps = 7/227 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR-INHPH 86
KVIG+GS+ KV A H +E +++ KV+ + K + E +VL++ + HP
Sbjct: 197 KVIGKGSFGKVLLARHKAEEVFYAV---KVLQKKAILKKKEEKHIMSERNVLLKNVKHPF 253
Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146
+V + FQ K + L + G+L L + E ++R + +I S L Y+H++NI
Sbjct: 254 LVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 313
Query: 147 AHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMP 206
+RDLK EN+L+ + ++ +TDFG + + + + T+CG+ Y APEVL PY
Sbjct: 314 VYRDLKPENILLDSQGHIVLTDFGLCK--ENIEHNSTTSTFCGTPEYLAPEVLHKQPY-D 370
Query: 207 KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVN 253
+ D W +G +LY ML PF + ++Y+ + + + + + N
Sbjct: 371 RTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN 417
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 126 bits (305), Expect = 9e-29
Identities = 69/227 (30%), Positives = 120/227 (52%), Gaps = 7/227 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR-INHPH 86
KVIG+GS+ KV A H +E +++ KV+ + K + E +VL++ + HP
Sbjct: 116 KVIGKGSFGKVLLARHKAEEVFYAV---KVLQKKAILKKKEEKHIMSERNVLLKNVKHPF 172
Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146
+V + FQ K + L + G+L L + E ++R + +I S L Y+H++NI
Sbjct: 173 LVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 232
Query: 147 AHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMP 206
+RDLK EN+L+ + ++ +TDFG + + + + T+CG+ Y APEVL PY
Sbjct: 233 VYRDLKPENILLDSQGHIVLTDFGLCK--ENIEHNSTTSTFCGTPEYLAPEVLHKQPY-D 289
Query: 207 KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVN 253
+ D W +G +LY ML PF + ++Y+ + + + + + N
Sbjct: 290 RTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN 336
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 126 bits (305), Expect = 9e-29
Identities = 69/227 (30%), Positives = 120/227 (52%), Gaps = 7/227 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR-INHPH 86
KVIG+GS+ KV A H +E +++ KV+ + K + E +VL++ + HP
Sbjct: 102 KVIGKGSFGKVLLARHKAEEVFYAV---KVLQKKAILKKKEEKHIMSERNVLLKNVKHPF 158
Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146
+V + FQ K + L + G+L L + E ++R + +I S L Y+H++NI
Sbjct: 159 LVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 218
Query: 147 AHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMP 206
+RDLK EN+L+ + ++ +TDFG + + + + T+CG+ Y APEVL PY
Sbjct: 219 VYRDLKPENILLDSQGHIVLTDFGLCK--ENIEHNSTTSTFCGTPEYLAPEVLHKQPY-D 275
Query: 207 KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVN 253
+ D W +G +LY ML PF + ++Y+ + + + + + N
Sbjct: 276 RTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN 322
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 126 bits (305), Expect = 9e-29
Identities = 69/227 (30%), Positives = 120/227 (52%), Gaps = 7/227 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR-INHPH 86
KVIG+GS+ KV A H +E +++ KV+ + K + E +VL++ + HP
Sbjct: 92 KVIGKGSFGKVLLARHKAEEVFYAV---KVLQKKAILKKKEEKHIMSERNVLLKNVKHPF 148
Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146
+V + FQ K + L + G+L L + E ++R + +I S L Y+H++NI
Sbjct: 149 LVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 208
Query: 147 AHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMP 206
+RDLK EN+L+ + ++ +TDFG + + + + T+CG+ Y APEVL PY
Sbjct: 209 VYRDLKPENILLDSQGHIVLTDFGLCK--ENIEHNSTTSTFCGTPEYLAPEVLHKQPY-D 265
Query: 207 KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVN 253
+ D W +G +LY ML PF + ++Y+ + + + + + N
Sbjct: 266 RTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN 312
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 126 bits (305), Expect = 9e-29
Identities = 69/227 (30%), Positives = 120/227 (52%), Gaps = 7/227 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR-INHPH 86
KVIG+GS+ KV A H +E +++ KV+ + K + E +VL++ + HP
Sbjct: 102 KVIGKGSFGKVLLARHKAEEVFYAV---KVLQKKAILKKKEEKHIMSERNVLLKNVKHPF 158
Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146
+V + FQ K + L + G+L L + E ++R + +I S L Y+H++NI
Sbjct: 159 LVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 218
Query: 147 AHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMP 206
+RDLK EN+L+ + ++ +TDFG + + + + T+CG+ Y APEVL PY
Sbjct: 219 VYRDLKPENILLDSQGHIVLTDFGLCK--ENIEHNSTTSTFCGTPEYLAPEVLHKQPY-D 275
Query: 207 KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVN 253
+ D W +G +LY ML PF + ++Y+ + + + + + N
Sbjct: 276 RTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN 322
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 126 bits (305), Expect = 9e-29
Identities = 69/227 (30%), Positives = 120/227 (52%), Gaps = 7/227 (3%)
Query: 28 KVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIR-INHPH 86
KVIG+GS+ KV A H +E +++ KV+ + K + E +VL++ + HP
Sbjct: 102 KVIGKGSFGKVLLARHKAEEVFYAV---KVLQKKAILKKKEEKHIMSERNVLLKNVKHPF 158
Query: 87 IVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNI 146
+V + FQ K + L + G+L L + E ++R + +I S L Y+H++NI
Sbjct: 159 LVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNI 218
Query: 147 AHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYMP 206
+RDLK EN+L+ + ++ +TDFG + + + + T+CG+ Y APEVL PY
Sbjct: 219 VYRDLKPENILLDSQGHIVLTDFGLCK--ENIEHNSTTSTFCGTPEYLAPEVLHKQPY-D 275
Query: 207 KLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVN 253
+ D W +G +LY ML PF + ++Y+ + + + + + N
Sbjct: 276 RTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITN 322
>AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinase
protein.
Length = 482
Score = 126 bits (305), Expect = 9e-29
Identities = 74/277 (26%), Positives = 142/277 (51%), Gaps = 10/277 (3%)
Query: 1 MGGGDKIDLSTTQSDIAV--LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVI 58
+G ++++L+ T ++ + F L +V+G+G Y KV++ + I A KV+
Sbjct: 42 VGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVL 101
Query: 59 DTAKAPRDYL-TKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLT 117
AK R+ T E ++L + HP IV ++ FQ K ++ L G+L L
Sbjct: 102 RKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLE 161
Query: 118 QNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQ 177
+ G E+ + ++ +I L ++H+ I +RDLK EN+++++ ++K+TDFG +
Sbjct: 162 REGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCK--ES 219
Query: 178 RDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237
++ T+CG++ Y APE+L + + D WS+G ++Y ML + PF + KK
Sbjct: 220 IHEGAVTHTFCGTIEYMAPEILVRSGH-NRAVDWWSLGALMYDMLTGSPPFTAENRKKTM 278
Query: 238 EKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSR 274
+K + R + + L+ + ++ V + ++ P R
Sbjct: 279 DKII----RGKLALPPYLTPDARDLVKKFLKRNPSQR 311
>AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase 14
beta protein.
Length = 482
Score = 126 bits (305), Expect = 9e-29
Identities = 74/277 (26%), Positives = 142/277 (51%), Gaps = 10/277 (3%)
Query: 1 MGGGDKIDLSTTQSDIAV--LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVI 58
+G ++++L+ T ++ + F L +V+G+G Y KV++ + I A KV+
Sbjct: 42 VGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVL 101
Query: 59 DTAKAPRDYL-TKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLT 117
AK R+ T E ++L + HP IV ++ FQ K ++ L G+L L
Sbjct: 102 RKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLE 161
Query: 118 QNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQ 177
+ G E+ + ++ +I L ++H+ I +RDLK EN+++++ ++K+TDFG +
Sbjct: 162 REGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCK--ES 219
Query: 178 RDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237
++ T+CG++ Y APE+L + + D WS+G ++Y ML + PF + KK
Sbjct: 220 IHEGAVTHTFCGTIEYMAPEILVRSGH-NRAVDWWSLGALMYDMLTGSPPFTAENRKKTM 278
Query: 238 EKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSR 274
+K + R + + L+ + ++ V + ++ P R
Sbjct: 279 DKII----RGKLALPPYLTPDARDLVKKFLKRNPSQR 311
>AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein
DKFZp761I032 variant protein.
Length = 796
Score = 126 bits (305), Expect = 9e-29
Identities = 90/329 (27%), Positives = 168/329 (51%), Gaps = 21/329 (6%)
Query: 14 SDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKA-PRDYLTKFL 72
S+ + L EK + + KVIG+G++A V + +D + A K+ID AK +++L +
Sbjct: 415 SESSTLLEK-YKIGKVIGDGNFAVVKEC---IDRSTGKEFALKIIDKAKCCGKEHL---I 467
Query: 73 PRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMR 132
E+ +L R+ HP+I+ + + + F+ + + GDL D +T + E +
Sbjct: 468 ENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVY 527
Query: 133 QIISGLQYIHTMNIAHRDLKCENVLV----TANYNVKITDFGFARNVRQRDRDVLSETYC 188
+ + L+Y+H ++I HRD+K EN+LV ++K+ DFG A V + T C
Sbjct: 528 NLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV-----EGPLYTVC 582
Query: 189 GSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKK-LYEKQVMRKWR 246
G+ +Y APE++ Y K+ D+W+ GVI Y +L PF +E ++++ L+++ + K
Sbjct: 583 GTPTYVAPEIIAETGYGLKV-DIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLE 641
Query: 247 FRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMD-SRLAKLTFLEESLLKQ 305
F + ++ KE ++Q+++ ++R TA + + W+ D S+ + LKQ
Sbjct: 642 FPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQ 701
Query: 306 AHEESQKRDNSTEEDSEVERIAELRRKGR 334
+ + NST V L ++G+
Sbjct: 702 HFNNALPKQNSTTTGVSVIMNTALDKEGQ 730
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 variant protein.
Length = 806
Score = 126 bits (305), Expect = 9e-29
Identities = 67/206 (32%), Positives = 113/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + + A KV+ A RD + + R D+L+ +
Sbjct: 135 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER--DILVEV 192
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 193 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 252
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ D + + ++CG++ Y APEV+
Sbjct: 253 SLGIIYRDLKPENILLDEEGHIKLTDFGLSK--ESIDHEKKAYSFCGTVEYMAPEVVNRR 310
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 311 GH-TQSADWWSFGVLMFEMLTGTLPF 335
Score = 113 bits (271), Expect = 1e-24
Identities = 77/272 (28%), Positives = 138/272 (50%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H ++ K+ID +K RD E+++L+R
Sbjct: 487 GYEVKEDIGVGSYSVCKRCIHKATNMEFAV---KIIDKSK--RDPT-----EEIEILLRY 536
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I ++Y+
Sbjct: 537 GQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYL 596
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H + HRDLK N+L V + N ++I DFGFA+ +R + L T C + ++ APE
Sbjct: 597 HAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG--LLMTPCYTANFVAPE 654
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+GV+LYTML PF + + +++ + K+ N
Sbjct: 655 VLKRQGY-DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNS 713
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA+ V WI
Sbjct: 714 VSDTAKDLVSKMLHVDPHQRLTAALVLRHPWI 745
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 126 bits (305), Expect = 9e-29
Identities = 67/206 (32%), Positives = 113/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + + A KV+ A RD + + R D+L+ +
Sbjct: 54 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMER--DILVEV 111
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GDL L++ E + ++ ++ L ++H
Sbjct: 112 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 171
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
++ I +RDLK EN+L+ ++K+TDFG ++ D + + ++CG++ Y APEV+
Sbjct: 172 SLGIIYRDLKPENILLDEEGHIKLTDFGLSK--ESIDHEKKAYSFCGTVEYMAPEVVNRR 229
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 230 GH-TQSADWWSFGVLMFEMLTGTLPF 254
Score = 113 bits (271), Expect = 1e-24
Identities = 77/272 (28%), Positives = 138/272 (50%), Gaps = 21/272 (7%)
Query: 23 GFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRI 82
G+ +++ IG GSY+ + H ++ K+ID +K RD E+++L+R
Sbjct: 407 GYEVKEDIGVGSYSVCKRCIHKATNMEFAV---KIIDKSK--RDPT-----EEIEILLRY 456
Query: 83 N-HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYI 141
HP+I+ + +++ ++ + G+LLD + + E ++ + I ++Y+
Sbjct: 457 GQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYL 516
Query: 142 HTMNIAHRDLKCENVL-VTANYN---VKITDFGFARNVRQRDRDVLSETYCGSLSYAAPE 197
H + HRDLK N+L V + N ++I DFGFA+ +R + L T C + ++ APE
Sbjct: 517 HAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG--LLMTPCYTANFVAPE 574
Query: 198 VLKGVPYMPKLADMWSIGVILYTMLNKALPF---NETSVKKLYEKQVMRKWRFRTTVVNQ 254
VLK Y D+WS+GV+LYTML PF + + +++ + K+ N
Sbjct: 575 VLKRQGY-DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNS 633
Query: 255 LSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
+S K+ V++++ +P R TA+ V WI
Sbjct: 634 VSDTAKDLVSKMLHVDPHQRLTAALVLRHPWI 665
>AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase
beta protein.
Length = 495
Score = 126 bits (305), Expect = 9e-29
Identities = 74/277 (26%), Positives = 142/277 (51%), Gaps = 10/277 (3%)
Query: 1 MGGGDKIDLSTTQSDIAV--LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVI 58
+G ++++L+ T ++ + F L +V+G+G Y KV++ + I A KV+
Sbjct: 55 VGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVL 114
Query: 59 DTAKAPRDYL-TKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLT 117
AK R+ T E ++L + HP IV ++ FQ K ++ L G+L L
Sbjct: 115 RKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLE 174
Query: 118 QNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQ 177
+ G E+ + ++ +I L ++H+ I +RDLK EN+++++ ++K+TDFG +
Sbjct: 175 REGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCK--ES 232
Query: 178 RDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237
++ T+CG++ Y APE+L + + D WS+G ++Y ML + PF + KK
Sbjct: 233 IHEGAVTHTFCGTIEYMAPEILVRSGH-NRAVDWWSLGALMYDMLTGSPPFTAENRKKTM 291
Query: 238 EKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSR 274
+K + R + + L+ + ++ V + ++ P R
Sbjct: 292 DKII----RGKLALPPYLTPDARDLVKKFLKRNPSQR 324
>AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein
protein.
Length = 716
Score = 126 bits (304), Expect = 1e-28
Identities = 90/329 (27%), Positives = 168/329 (51%), Gaps = 21/329 (6%)
Query: 14 SDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKA-PRDYLTKFL 72
S+ + L EK + + KVIG+G++A V + +D + A K+ID AK +++L +
Sbjct: 335 SESSTLLEK-YKIGKVIGDGNFAVVKEC---IDRSTGKEFALKIIDKAKCCGKEHL---I 387
Query: 73 PRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMR 132
E+ +L R+ HP+I+ + + + F+ + + GDL D +T + E +
Sbjct: 388 ENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVY 447
Query: 133 QIISGLQYIHTMNIAHRDLKCENVLV----TANYNVKITDFGFARNVRQRDRDVLSETYC 188
+ + L+Y+H ++I HRD+K EN+LV ++K+ DFG A V + T C
Sbjct: 448 NLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV-----EGPLYTVC 502
Query: 189 GSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKK-LYEKQVMRKWR 246
G+ +Y APE++ Y K+ D+W+ GVI Y +L PF +E ++++ L+++ + K
Sbjct: 503 GTPTYVAPEIIAETGYGLKV-DIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLE 561
Query: 247 FRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMD-SRLAKLTFLEESLLKQ 305
F + ++ KE ++Q+++ ++R TA + + W+ D S+ + LKQ
Sbjct: 562 FPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQ 621
Query: 306 AHEESQKRDNSTEEDSEVERIAELRRKGR 334
+ + NST V L ++G+
Sbjct: 622 HFNNALPKQNSTTTGVSVIMNTVLDKEGQ 650
>BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 126 bits (303), Expect = 2e-28
Identities = 87/300 (29%), Positives = 151/300 (50%), Gaps = 16/300 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK IG+GS+ +V+K +D ++A K+ID +A + + + +E+ VL + + P
Sbjct: 27 LEK-IGKGSFGEVFKG---IDNRTQKVVAIKIIDLEEAEDEI--EDIQQEITVLSQCDSP 80
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++ + + K +I + + G LD L + G + E Q +R+I+ GL Y+H+
Sbjct: 81 YVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEK 139
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
HRD+K NVL++ + VK+ DFG A + D + T+ G+ + APEV+K Y
Sbjct: 140 KIHRDIKAANVLLSEHGEVKLADFGVAGQL--TDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K AD+WS+G+ + P +E K+ + T+ S KE V
Sbjct: 198 SK-ADIWSLGITAIELARGEPPHSELHPMKVL---FLIPKNNPPTLEGNYSKPLKEFVEA 253
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLK-QAHEESQKRDNSTEEDSEVE 324
+ EP RPTA + +I +++ K ++L E + + + + Q D+S+ EDS+ E
Sbjct: 254 CLNKEPSFRPTAKELLKHKFILRNAK--KTSYLTELIDRYKRWKAEQSHDDSSSEDSDAE 311
>BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 126 bits (303), Expect = 2e-28
Identities = 87/300 (29%), Positives = 151/300 (50%), Gaps = 16/300 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK IG+GS+ +V+K +D ++A K+ID +A + + + +E+ VL + + P
Sbjct: 27 LEK-IGKGSFGEVFKG---IDNRTQKVVAIKIIDLEEAEDEI--EDIQQEITVLSQCDSP 80
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++ + + K +I + + G LD L + G + E Q +R+I+ GL Y+H+
Sbjct: 81 YVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEK 139
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
HRD+K NVL++ + VK+ DFG A + D + T+ G+ + APEV+K Y
Sbjct: 140 KIHRDIKAANVLLSEHGEVKLADFGVAGQL--TDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K AD+WS+G+ + P +E K+ + T+ S KE V
Sbjct: 198 SK-ADIWSLGITAIELARGEPPHSELHPMKVL---FLIPKNNPPTLEGNYSKPLKEFVEA 253
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLK-QAHEESQKRDNSTEEDSEVE 324
+ EP RPTA + +I +++ K ++L E + + + + Q D+S+ EDS+ E
Sbjct: 254 CLNKEPSFRPTAKELLKHKFILRNAK--KTSYLTELIDRYKRWKAEQSHDDSSSEDSDAE 311
>BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 126 bits (303), Expect = 2e-28
Identities = 87/300 (29%), Positives = 151/300 (50%), Gaps = 16/300 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK IG+GS+ +V+K +D ++A K+ID +A + + + +E+ VL + + P
Sbjct: 27 LEK-IGKGSFGEVFKG---IDNRTQKVVAIKIIDLEEAEDEI--EDIQQEITVLSQCDSP 80
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++ + + K +I + + G LD L + G + E Q +R+I+ GL Y+H+
Sbjct: 81 YVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEK 139
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
HRD+K NVL++ + VK+ DFG A + D + T+ G+ + APEV+K Y
Sbjct: 140 KIHRDIKAANVLLSEHGEVKLADFGVAGQL--TDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K AD+WS+G+ + P +E K+ + T+ S KE V
Sbjct: 198 SK-ADIWSLGITAIELARGEPPHSELHPMKVL---FLIPKNNPPTLEGNYSKPLKEFVEA 253
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLK-QAHEESQKRDNSTEEDSEVE 324
+ EP RPTA + +I +++ K ++L E + + + + Q D+S+ EDS+ E
Sbjct: 254 CLNKEPSFRPTAKELLKHKFILRNAK--KTSYLTELIDRYKRWKAEQSHDDSSSEDSDAE 311
>AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 126 bits (303), Expect = 2e-28
Identities = 87/300 (29%), Positives = 151/300 (50%), Gaps = 16/300 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK IG+GS+ +V+K +D ++A K+ID +A + + + +E+ VL + + P
Sbjct: 27 LEK-IGKGSFGEVFKG---IDNRTQKVVAIKIIDLEEAEDEI--EDIQQEITVLSQCDSP 80
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++ + + K +I + + G LD L + G + E Q +R+I+ GL Y+H+
Sbjct: 81 YVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEK 139
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
HRD+K NVL++ + VK+ DFG A + D + T+ G+ + APEV+K Y
Sbjct: 140 KIHRDIKAANVLLSEHGEVKLADFGVAGQL--TDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K AD+WS+G+ + P +E K+ + T+ S KE V
Sbjct: 198 SK-ADIWSLGITAIELARGEPPHSELHPMKVL---FLIPKNNPPTLEGNYSKPLKEFVEA 253
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLK-QAHEESQKRDNSTEEDSEVE 324
+ EP RPTA + +I +++ K ++L E + + + + Q D+S+ EDS+ E
Sbjct: 254 CLNKEPSFRPTAKELLKHKFILRNAK--KTSYLTELIDRYKRWKAEQSHDDSSSEDSDAE 311
>AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 126 bits (303), Expect = 2e-28
Identities = 87/300 (29%), Positives = 151/300 (50%), Gaps = 16/300 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK IG+GS+ +V+K +D ++A K+ID +A + + + +E+ VL + + P
Sbjct: 39 LEK-IGKGSFGEVFKG---IDNRTQKVVAIKIIDLEEAEDEI--EDIQQEITVLSQCDSP 92
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++ + + K +I + + G LD L + G + E Q +R+I+ GL Y+H+
Sbjct: 93 YVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEK 151
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
HRD+K NVL++ + VK+ DFG A + D + T+ G+ + APEV+K Y
Sbjct: 152 KIHRDIKAANVLLSEHGEVKLADFGVAGQL--TDTQIKRNTFVGTPFWMAPEVIKQSAYD 209
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K AD+WS+G+ + P +E K+ + T+ S KE V
Sbjct: 210 SK-ADIWSLGITAIELARGEPPHSELHPMKVL---FLIPKNNPPTLEGNYSKPLKEFVEA 265
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLK-QAHEESQKRDNSTEEDSEVE 324
+ EP RPTA + +I +++ K ++L E + + + + Q D+S+ EDS+ E
Sbjct: 266 CLNKEPSFRPTAKELLKHKFILRNAK--KTSYLTELIDRYKRWKAEQSHDDSSSEDSDAE 323
>AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 126 bits (303), Expect = 2e-28
Identities = 87/300 (29%), Positives = 151/300 (50%), Gaps = 16/300 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK IG+GS+ +V+K +D ++A K+ID +A + + + +E+ VL + + P
Sbjct: 27 LEK-IGKGSFGEVFKG---IDNRTQKVVAIKIIDLEEAEDEI--EDIQQEITVLSQCDSP 80
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++ + + K +I + + G LD L + G + E Q +R+I+ GL Y+H+
Sbjct: 81 YVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEK 139
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
HRD+K NVL++ + VK+ DFG A + D + T+ G+ + APEV+K Y
Sbjct: 140 KIHRDIKAANVLLSEHGEVKLADFGVAGQL--TDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K AD+WS+G+ + P +E K+ + T+ S KE V
Sbjct: 198 SK-ADIWSLGITAIELARGEPPHSELHPMKVL---FLIPKNNPPTLEGNYSKPLKEFVEA 253
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLK-QAHEESQKRDNSTEEDSEVE 324
+ EP RPTA + +I +++ K ++L E + + + + Q D+S+ EDS+ E
Sbjct: 254 CLNKEPSFRPTAKELLKHKFILRNAK--KTSYLTELIDRYKRWKAEQSHDDSSSEDSDAE 311
>AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 126 bits (303), Expect = 2e-28
Identities = 87/300 (29%), Positives = 151/300 (50%), Gaps = 16/300 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK IG+GS+ +V+K +D ++A K+ID +A + + + +E+ VL + + P
Sbjct: 39 LEK-IGKGSFGEVFKG---IDNRTQKVVAIKIIDLEEAEDEI--EDIQQEITVLSQCDSP 92
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++ + + K +I + + G LD L + G + E Q +R+I+ GL Y+H+
Sbjct: 93 YVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEK 151
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
HRD+K NVL++ + VK+ DFG A + D + T+ G+ + APEV+K Y
Sbjct: 152 KIHRDIKAANVLLSEHGEVKLADFGVAGQL--TDTQIKRNTFVGTPFWMAPEVIKQSAYD 209
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K AD+WS+G+ + P +E K+ + T+ S KE V
Sbjct: 210 SK-ADIWSLGITAIELARGEPPHSELHPMKVL---FLIPKNNPPTLEGNYSKPLKEFVEA 265
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLK-QAHEESQKRDNSTEEDSEVE 324
+ EP RPTA + +I +++ K ++L E + + + + Q D+S+ EDS+ E
Sbjct: 266 CLNKEPSFRPTAKELLKHKFILRNAK--KTSYLTELIDRYKRWKAEQSHDDSSSEDSDAE 323
>AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-like
protein kinase 3 protein.
Length = 443
Score = 126 bits (303), Expect = 2e-28
Identities = 87/300 (29%), Positives = 151/300 (50%), Gaps = 16/300 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK IG+GS+ +V+K +D ++A K+ID +A + + + +E+ VL + + P
Sbjct: 39 LEK-IGKGSFGEVFKG---IDNRTQKVVAIKIIDLEEAEDEI--EDIQQEITVLSQCDSP 92
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++ + + K +I + + G LD L + G + E Q +R+I+ GL Y+H+
Sbjct: 93 YVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEK 151
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
HRD+K NVL++ + VK+ DFG A + D + T+ G+ + APEV+K Y
Sbjct: 152 KIHRDIKAANVLLSEHGEVKLADFGVAGQL--TDTQIKRNTFVGTPFWMAPEVIKQSAYD 209
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K AD+WS+G+ + P +E K+ + T+ S KE V
Sbjct: 210 SK-ADIWSLGITAIELARGEPPHSELHPMKVL---FLIPKNNPPTLEGNYSKPLKEFVEA 265
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLK-QAHEESQKRDNSTEEDSEVE 324
+ EP RPTA + +I +++ K ++L E + + + + Q D+S+ EDS+ E
Sbjct: 266 CLNKEPSFRPTAKELLKHKFILRNAK--KTSYLTELIDRYKRWKAEQSHDDSSSEDSDAE 323
>AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3
protein.
Length = 431
Score = 126 bits (303), Expect = 2e-28
Identities = 87/300 (29%), Positives = 151/300 (50%), Gaps = 16/300 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK IG+GS+ +V+K +D ++A K+ID +A + + + +E+ VL + + P
Sbjct: 27 LEK-IGKGSFGEVFKG---IDNRTQKVVAIKIIDLEEAEDEI--EDIQQEITVLSQCDSP 80
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++ + + K +I + + G LD L + G + E Q +R+I+ GL Y+H+
Sbjct: 81 YVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEK 139
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
HRD+K NVL++ + VK+ DFG A + D + T+ G+ + APEV+K Y
Sbjct: 140 KIHRDIKAANVLLSEHGEVKLADFGVAGQL--TDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K AD+WS+G+ + P +E K+ + T+ S KE V
Sbjct: 198 SK-ADIWSLGITAIELARGEPPHSELHPMKVL---FLIPKNNPPTLEGNYSKPLKEFVEA 253
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLK-QAHEESQKRDNSTEEDSEVE 324
+ EP RPTA + +I +++ K ++L E + + + + Q D+S+ EDS+ E
Sbjct: 254 CLNKEPSFRPTAKELLKHKFILRNAK--KTSYLTELIDRYKRWKAEQSHDDSSSEDSDAE 311
>AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens
cDNA FLJ16392 fis, clone TRACH2020048, moderately
similar to Mus musculus serine/threonine-protein kinase
NEK3 (Nek3) mRNA. ).
Length = 510
Score = 125 bits (302), Expect = 2e-28
Identities = 90/339 (26%), Positives = 164/339 (48%), Gaps = 20/339 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
+++ ++IGEGS+ + H E+ + + A K I K+ + T+ +E +L ++
Sbjct: 25 YMVLRMIGEGSFGRALLVQH---ESSNQMFAMKEIRLPKSFSN--TQNSRKEAVLLAKMK 79
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGA--IPENQSRLWMRQIISGLQYI 141
HP+IV F+ +I + + + GDL+ + Q PE+ W Q+ G+ +I
Sbjct: 80 HPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHI 139
Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKG 201
H + HRD+K +N+ +T N VK+ DFG AR + + + TY G+ Y PE+ +
Sbjct: 140 HKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLL--SNPMAFACTYVGTPYYVPPEIWEN 197
Query: 202 VPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKE 261
+PY K +D+WS+G ILY + PF S K L K + + + S E +
Sbjct: 198 LPYNNK-SDIWSLGCILYELCTLKHPFQANSWKNLILKVCQ---GCISPLPSHYSYELQF 253
Query: 262 QVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLKQAHEESQKRDNSTEEDS 321
V Q+ + P RP+A+ + + G+ +RL + E +++ E ++ NS
Sbjct: 254 LVKQMFKRNPSHRPSATTLLSR---GIVARLVQKCLPPEIIMEYGEEVLEEIKNSKHNTP 310
Query: 322 EVERIAELRRKGRGKEGLKVLKNVDANYAKSLYLFENKD 360
++ E RKG + L++++ N +S N++
Sbjct: 311 RKKQEEEQDRKGSHTD----LESINENLVESALRRVNRE 345
>AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein.
Length = 443
Score = 125 bits (302), Expect = 2e-28
Identities = 87/312 (27%), Positives = 162/312 (51%), Gaps = 21/312 (6%)
Query: 14 SDIAVLQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKA-PRDYLTKFL 72
S+ + L EK + + KVIG+G++A V + +D + A K+ID AK +++L +
Sbjct: 132 SESSTLLEK-YKIGKVIGDGNFAVVKEC---IDRSTGKEFALKIIDKAKCCGKEHL---I 184
Query: 73 PRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMR 132
E+ +L R+ HP+I+ + + + F+ + + GDL D +T + E +
Sbjct: 185 ENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVY 244
Query: 133 QIISGLQYIHTMNIAHRDLKCENVLV----TANYNVKITDFGFARNVRQRDRDVLSETYC 188
+ + L+Y+H ++I HRD+K EN+LV ++K+ DFG A V + T C
Sbjct: 245 NLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVV-----EGPLYTVC 299
Query: 189 GSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKK-LYEKQVMRKWR 246
G+ +Y APE++ Y K+ D+W+ GVI Y +L PF +E ++++ L+++ + K
Sbjct: 300 GTPTYVAPEIIAETGYGLKV-DIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLE 358
Query: 247 FRTTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWIGMD-SRLAKLTFLEESLLKQ 305
F + ++ KE ++Q+++ ++R TA + + W+ D S+ + LKQ
Sbjct: 359 FPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQ 418
Query: 306 AHEESQKRDNST 317
+ + NST
Sbjct: 419 HFNNALPKQNST 430
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 125 bits (301), Expect = 3e-28
Identities = 73/268 (27%), Positives = 137/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A ++ H I+A KV+ ++ ++ + L RE+++ ++
Sbjct: 104 FEIGRPLGKGKFGNVYLAR---EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 160
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F R + ++ L +A G+L L ++ E ++ M ++ L Y H
Sbjct: 161 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 220
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ +KI DFG++ + R +T CG+L Y PE+++G
Sbjct: 221 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRM 276
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
+ K+ D+W IGV+ Y +L PF S + Y + V +F +V ++ +
Sbjct: 277 HNEKV-DLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASV----PMGAQDLI 331
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ P R + V W+ +SR
Sbjct: 332 SKLLRHNPSERLPLAQVSAHPWVRANSR 359
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 125 bits (301), Expect = 3e-28
Identities = 73/268 (27%), Positives = 137/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A ++ H I+A KV+ ++ ++ + L RE+++ ++
Sbjct: 77 FEIGRPLGKGKFGNVYLAR---EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F R + ++ L +A G+L L ++ E ++ M ++ L Y H
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ +KI DFG++ + R +T CG+L Y PE+++G
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRM 249
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
+ K+ D+W IGV+ Y +L PF S + Y + V +F +V ++ +
Sbjct: 250 HNEKV-DLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASV----PMGAQDLI 304
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ P R + V W+ +SR
Sbjct: 305 SKLLRHNPSERLPLAQVSAHPWVRANSR 332
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 124 bits (300), Expect = 4e-28
Identities = 75/271 (27%), Positives = 136/271 (50%), Gaps = 10/271 (3%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
E + + + +G G +A V K ++ K + + R + + RE+++L
Sbjct: 10 EDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILR 69
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
I HP+I+ + +IF+ + + L G+L DFL + ++ E+++ +++QI+ G+ Y
Sbjct: 70 EIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHY 129
Query: 141 IHTMNIAHRDLKCENVLV----TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAP 196
+H+ IAH DLK EN+++ N +K+ DFG A + + + G+ + AP
Sbjct: 130 LHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNE---FKNIFGTPEFVAP 186
Query: 197 EVLKGVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKKLYEKQVMRKWRFRTTVVNQL 255
E++ P + ADMWSIGVI Y +L+ A PF ET + L + + F +
Sbjct: 187 EIVNYEP-LGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAV-NYDFDEEYFSNT 244
Query: 256 STECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
S K+ + +L+ +PK R T + +WI
Sbjct: 245 SELAKDFIRRLLVKDPKRRMTIAQSLEHSWI 275
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 124 bits (300), Expect = 4e-28
Identities = 75/271 (27%), Positives = 136/271 (50%), Gaps = 10/271 (3%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
E + + + +G G +A V K ++ K + + R + + RE+++L
Sbjct: 10 EDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILR 69
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
I HP+I+ + +IF+ + + L G+L DFL + ++ E+++ +++QI+ G+ Y
Sbjct: 70 EIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHY 129
Query: 141 IHTMNIAHRDLKCENVLV----TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAP 196
+H+ IAH DLK EN+++ N +K+ DFG A + + + G+ + AP
Sbjct: 130 LHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNE---FKNIFGTPEFVAP 186
Query: 197 EVLKGVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKKLYEKQVMRKWRFRTTVVNQL 255
E++ P + ADMWSIGVI Y +L+ A PF ET + L + + F +
Sbjct: 187 EIVNYEP-LGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAV-NYDFDEEYFSNT 244
Query: 256 STECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
S K+ + +L+ +PK R T + +WI
Sbjct: 245 SELAKDFIRRLLVKDPKRRMTIAQSLEHSWI 275
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 124 bits (300), Expect = 4e-28
Identities = 75/271 (27%), Positives = 136/271 (50%), Gaps = 10/271 (3%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
E + + + +G G +A V K ++ K + + R + + RE+++L
Sbjct: 10 EDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILR 69
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
I HP+I+ + +IF+ + + L G+L DFL + ++ E+++ +++QI+ G+ Y
Sbjct: 70 EIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHY 129
Query: 141 IHTMNIAHRDLKCENVLV----TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAP 196
+H+ IAH DLK EN+++ N +K+ DFG A + + + G+ + AP
Sbjct: 130 LHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNE---FKNIFGTPEFVAP 186
Query: 197 EVLKGVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKKLYEKQVMRKWRFRTTVVNQL 255
E++ P + ADMWSIGVI Y +L+ A PF ET + L + + F +
Sbjct: 187 EIVNYEP-LGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAV-NYDFDEEYFSNT 244
Query: 256 STECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
S K+ + +L+ +PK R T + +WI
Sbjct: 245 SELAKDFIRRLLVKDPKRRMTIAQSLEHSWI 275
>AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein.
Length = 481
Score = 124 bits (300), Expect = 4e-28
Identities = 75/277 (27%), Positives = 142/277 (51%), Gaps = 11/277 (3%)
Query: 1 MGGGDKIDLSTTQSDIAV--LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVI 58
+G ++++L+ T ++ + F L +V+G+G Y KV++ V I A KV+
Sbjct: 42 VGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQV-RKVQGNLGKIYAMKVL 100
Query: 59 DTAKAPRDYL-TKFLPRELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLT 117
AK R+ T E ++L + HP IV ++ FQ K ++ L G+L L
Sbjct: 101 RKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLE 160
Query: 118 QNGAIPENQSRLWMRQIISGLQYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQ 177
+ G E+ + ++ +I L ++H+ I +RDLK EN+++++ ++K+TDFG +
Sbjct: 161 REGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCK--ES 218
Query: 178 RDRDVLSETYCGSLSYAAPEVLKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLY 237
++ T+CG++ Y APE+L + + D WS+G ++Y ML + PF + KK
Sbjct: 219 IHEGAVTHTFCGTIEYMAPEILVRSGH-NRAVDWWSLGALMYDMLTGSPPFTAENRKKTM 277
Query: 238 EKQVMRKWRFRTTVVNQLSTECKEQVTQLMEPEPKSR 274
+K + R + + L+ + ++ V + ++ P R
Sbjct: 278 DKII----RGKLALPPYLTPDARDLVKKFLKRNPSQR 310
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 124 bits (300), Expect = 4e-28
Identities = 75/271 (27%), Positives = 136/271 (50%), Gaps = 10/271 (3%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
E + + + +G G +A V K ++ K + + R + + RE+++L
Sbjct: 10 EDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILR 69
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
I HP+I+ + +IF+ + + L G+L DFL + ++ E+++ +++QI+ G+ Y
Sbjct: 70 EIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHY 129
Query: 141 IHTMNIAHRDLKCENVLV----TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAP 196
+H+ IAH DLK EN+++ N +K+ DFG A + + + G+ + AP
Sbjct: 130 LHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNE---FKNIFGTPEFVAP 186
Query: 197 EVLKGVPYMPKLADMWSIGVILYTMLNKALPF-NETSVKKLYEKQVMRKWRFRTTVVNQL 255
E++ P + ADMWSIGVI Y +L+ A PF ET + L + + F +
Sbjct: 187 EIVNYEP-LGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAV-NYDFDEEYFSNT 244
Query: 256 STECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
S K+ + +L+ +PK R T + +WI
Sbjct: 245 SELAKDFIRRLLVKDPKRRMTIAQSLEHSWI 275
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 124 bits (299), Expect = 5e-28
Identities = 73/268 (27%), Positives = 138/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A + E+ H I+A KV+ ++ ++ L L RE+++ +
Sbjct: 9 FEIGRPLGKGKFGNVYLAR--LKES-HFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 65
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F + ++ L +A G+L L ++ + E ++ + ++ L Y H
Sbjct: 66 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTYCHD 125
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ VKI DFG++ + +R +T CG+L Y PE+++G
Sbjct: 126 KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPER----KTMCGTLDYLPPEMIEGRT 181
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y K+ D+W IGV+ Y +L PF S + Y + + RF + + ++ +
Sbjct: 182 YDEKV-DLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLS----MPLGARDLI 236
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ +P R + + W+ SR
Sbjct: 237 SRLLRYQPLERLPLAQILKHPWVQAHSR 264
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 124 bits (298), Expect = 6e-28
Identities = 79/254 (31%), Positives = 134/254 (52%), Gaps = 13/254 (5%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
EK +LE +IGEGS+ +VYK ++A K I L L RE++++
Sbjct: 2 EKYHVLE-MIGEGSFGRVYKGRRKYSA---QVVALKFIPKLGRSEKELRN-LQREIEIMR 56
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+ HP+IVH+ + F+ + + +AE G+L L +G +PE+Q + Q++S L Y
Sbjct: 57 GLRHPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYY 115
Query: 141 IHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200
+H+ I HRD+K +N+L+ +K+ DFGFAR ++ + G+ Y +PE+++
Sbjct: 116 LHSHRILHRDMKPQNILLAKGGGIKLCDFGFAR--AMSTNTMVLTSIKGTPLYMSPELVE 173
Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECK 260
PY AD+WS+G ILY + PF TS+ +L + R+ +T+ S K
Sbjct: 174 ERPY-DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTI----SPCFK 228
Query: 261 EQVTQLMEPEPKSR 274
+ + L+ +P+ R
Sbjct: 229 DFLQGLLTKDPRQR 242
>CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein.
Length = 431
Score = 123 bits (297), Expect = 8e-28
Identities = 86/300 (28%), Positives = 150/300 (50%), Gaps = 16/300 (5%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
LEK IG+GS+ +V+K +D ++A K+ID +A + + + +E+ VL + + P
Sbjct: 27 LEK-IGKGSFGEVFKG---IDNRTQKVVAIKIIDLEEAEDEI--EDIQQEITVLSQCDSP 80
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++ + + K +I + + G LD L + G + E Q +R+I+ GL Y+H+
Sbjct: 81 YVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEK 139
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
HRD+K NVL++ + VK+ D G A + D + T+ G+ + APEV+K Y
Sbjct: 140 KIHRDIKAANVLLSEHGEVKLADIGVAGQL--TDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
K AD+WS+G+ + P +E K+ + T+ S KE V
Sbjct: 198 SK-ADIWSLGITAIELARGEPPHSELHPMKVL---FLIPKNNPPTLEGNYSKPLKEFVEA 253
Query: 266 LMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLK-QAHEESQKRDNSTEEDSEVE 324
+ EP RPTA + +I +++ K ++L E + + + + Q D+S+ EDS+ E
Sbjct: 254 CLNKEPSFRPTAKELLKHKFILRNAK--KTSYLTELIDRYKRWKAEQSHDDSSSEDSDAE 311
>CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein.
Length = 586
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 316 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 374
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 375 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 431
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 432 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 491
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 492 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 529
>BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 5 protein.
Length = 549
Score = 123 bits (297), Expect = 8e-28
Identities = 71/256 (27%), Positives = 129/256 (50%), Gaps = 4/256 (1%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDYLTKFLPRELDVLI 80
+ F L KV+G G+Y KV+ + + A KV+ A + T+ E VL
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 81 RINH-PHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQ 139
I P +V + FQ K + L + G+L L+Q E++ ++++ +I+ L+
Sbjct: 107 HIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALE 166
Query: 140 YIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL 199
++H + I +RD+K EN+L+ +N +V +TDFG ++ D + ++CG++ Y AP+++
Sbjct: 167 HLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEF-VADETERAYSFCGTIEYMAPDIV 225
Query: 200 KGVPY-MPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258
+G K D WS+GV++Y +L A PF K + R + ++S
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSAL 285
Query: 259 CKEQVTQLMEPEPKSR 274
K+ + +L+ +PK R
Sbjct: 286 AKDLIQRLLMKDPKKR 301
Score = 51.6 bits (118), Expect = 4e-06
Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 10/129 (7%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVL-IRINHP 85
+K +GEGS++ K H + + A K+I +E+ L + HP
Sbjct: 429 DKPLGEGSFSICRKCVH---KKSNQAFAVKIISKRMEANTQ------KEITALKLCEGHP 479
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + +F + F+ + G+L + + + E ++ MR+++S + ++H +
Sbjct: 480 NIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVG 539
Query: 146 IAHRDLKCE 154
+ HRDLK E
Sbjct: 540 VVHRDLKPE 548
>BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 388
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 389 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 448
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 449 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 486
>AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 388
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 389 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 448
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 449 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 486
>AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2
transcript variant del2-3 protein.
Length = 452
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 182 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 240
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 241 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 297
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 298 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 357
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 358 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 395
>AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2
transcript variant insX protein.
Length = 586
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 316 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 374
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 375 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 431
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 432 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 491
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 492 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 529
>AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 388
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 389 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 448
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 449 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 486
>AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 388
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 389 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 448
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 449 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 486
>AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein.
Length = 543
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 388
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 389 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 448
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 449 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 486
>AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein.
Length = 322
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 52 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 110
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 111 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 167
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 168 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 227
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 228 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 265
>AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2
protein.
Length = 543
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 388
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 389 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 448
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 449 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 486
>AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein.
Length = 543
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 388
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 389 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 448
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 449 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 486
>AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kinase
protein.
Length = 809
Score = 123 bits (297), Expect = 8e-28
Identities = 71/256 (27%), Positives = 129/256 (50%), Gaps = 4/256 (1%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDYLTKFLPRELDVLI 80
+ F L KV+G G+Y KV+ + + A KV+ A + T+ E VL
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 81 RINH-PHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQ 139
I P +V + FQ K + L + G+L L+Q E++ ++++ +I+ L+
Sbjct: 107 HIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALE 166
Query: 140 YIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL 199
++H + I +RD+K EN+L+ +N +V +TDFG ++ D + ++CG++ Y AP+++
Sbjct: 167 HLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEF-VADETERAYSFCGTIEYMAPDIV 225
Query: 200 KGVPY-MPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258
+G K D WS+GV++Y +L A PF K + R + ++S
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSAL 285
Query: 259 CKEQVTQLMEPEPKSR 274
K+ + +L+ +PK R
Sbjct: 286 AKDLIQRLLMKDPKKR 301
Score = 115 bits (276), Expect = 3e-25
Identities = 82/288 (28%), Positives = 137/288 (47%), Gaps = 23/288 (7%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVL-IRINHP 85
+K +GEGS++ K H + + + K+I +E+ L + HP
Sbjct: 429 DKPLGEGSFSICRKCVH---KKSNQALQVKIISKRMEANTQ------KEITALKLCEGHP 479
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + +F + F+ + G+L D L + E ++ MR+++S L ++H +
Sbjct: 480 NIVKLHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLG 539
Query: 146 IAHRDLKCENVLVT---ANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
+ HRDLK EN+L T N +KI DFGFAR ++ D L +T C +L PE+L
Sbjct: 540 VVHRDLKPENLLFTDENDNLEIKIIDFGFAR-LKPPDNQPL-KTPCFTLHSCRPELLNQN 597
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNE-------TSVKKLYEKQVMRKWRFRTTVVNQL 255
Y + D+WS+GVILYTML+ +PF TS ++ +K + F +
Sbjct: 598 GY-DESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNV 656
Query: 256 STECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLL 303
S E K+ + L+ +P R S + W+ S+L+ + +L
Sbjct: 657 SQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDIL 704
>AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2
protein.
Length = 543
Score = 123 bits (297), Expect = 8e-28
Identities = 72/218 (33%), Positives = 117/218 (53%), Gaps = 10/218 (4%)
Query: 75 ELDVLIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQI 134
E+++L ++NHP I+ + N F Y+I L E G+L D + N + E +L+ Q+
Sbjct: 273 EIEILKKLNHPCIIKIKNFFDAE-DYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQM 331
Query: 135 ISGLQYIHTMNIAHRDLKCENVLVTANYN---VKITDFGFARNVRQRDRDVLSETYCGSL 191
+ +QY+H I HRDLK ENVL+++ +KITDFG ++ + + L T CG+
Sbjct: 332 LLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETS---LMRTLCGTP 388
Query: 192 SYAAPEVL--KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMR-KWRFR 248
+Y APEVL G + D WS+GVIL+ L+ PF+E + + Q+ K+ F
Sbjct: 389 TYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFI 448
Query: 249 TTVVNQLSTECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
V ++S + + V +L+ +PK+R T W+
Sbjct: 449 PEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL 486
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase
RLPK protein.
Length = 802
Score = 123 bits (297), Expect = 8e-28
Identities = 71/256 (27%), Positives = 129/256 (50%), Gaps = 4/256 (1%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDYLTKFLPRELDVLI 80
+ F L KV+G G+Y KV+ + + A KV+ A + T+ E VL
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 81 RINH-PHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQ 139
I P +V + FQ K + L + G+L L+Q E++ ++++ +I+ L+
Sbjct: 107 HIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALE 166
Query: 140 YIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL 199
++H + I +RD+K EN+L+ +N +V +TDFG ++ D + ++CG++ Y AP+++
Sbjct: 167 HLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEF-VADETERAYSFCGTIEYMAPDIV 225
Query: 200 KGVPY-MPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258
+G K D WS+GV++Y +L A PF K + R + ++S
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSAL 285
Query: 259 CKEQVTQLMEPEPKSR 274
K+ + +L+ +PK R
Sbjct: 286 AKDLIQRLLMKDPKKR 301
Score = 119 bits (286), Expect = 2e-26
Identities = 83/288 (28%), Positives = 140/288 (48%), Gaps = 23/288 (7%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVL-IRINHP 85
+K +GEGS++ K H + + A K+I +E+ L + HP
Sbjct: 429 DKPLGEGSFSICRKCVH---KKSNQAFAVKIISKRMEANTQ------KEITALKLCEGHP 479
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + +F + F+ + G+L + + + E ++ MR+++S + ++H +
Sbjct: 480 NIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVG 539
Query: 146 IAHRDLKCENVLVT---ANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
+ HRDLK EN+L T N +KI DFGFAR ++ D L +T C +L YAAPE+L
Sbjct: 540 VVHRDLKPENLLFTDENDNLEIKIIDFGFAR-LKPPDNQPL-KTPCFTLHYAAPELLNQN 597
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNE-------TSVKKLYEKQVMRKWRFRTTVVNQL 255
Y + D+WS+GVILYTML+ +PF TS ++ +K + F +
Sbjct: 598 GY-DESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNV 656
Query: 256 STECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLL 303
S E K+ + L+ +P R S + W+ S+L+ + +L
Sbjct: 657 SQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDIL 704
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 123 bits (297), Expect = 8e-28
Identities = 71/256 (27%), Positives = 129/256 (50%), Gaps = 4/256 (1%)
Query: 22 KGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDYLTKFLPRELDVLI 80
+ F L KV+G G+Y KV+ + + A KV+ A + T+ E VL
Sbjct: 47 ENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLE 106
Query: 81 RINH-PHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQ 139
I P +V + FQ K + L + G+L L+Q E++ ++++ +I+ L+
Sbjct: 107 HIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALE 166
Query: 140 YIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL 199
++H + I +RD+K EN+L+ +N +V +TDFG ++ D + ++CG++ Y AP+++
Sbjct: 167 HLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEF-VADETERAYSFCGTIEYMAPDIV 225
Query: 200 KGVPY-MPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTE 258
+G K D WS+GV++Y +L A PF K + R + ++S
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSAL 285
Query: 259 CKEQVTQLMEPEPKSR 274
K+ + +L+ +PK R
Sbjct: 286 AKDLIQRLLMKDPKKR 301
Score = 119 bits (286), Expect = 2e-26
Identities = 83/288 (28%), Positives = 140/288 (48%), Gaps = 23/288 (7%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVL-IRINHP 85
+K +GEGS++ K H + + A K+I +E+ L + HP
Sbjct: 429 DKPLGEGSFSICRKCVH---KKSNQAFAVKIISKRMEANTQ------KEITALKLCEGHP 479
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
+IV + +F + F+ + G+L + + + E ++ MR+++S + ++H +
Sbjct: 480 NIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVG 539
Query: 146 IAHRDLKCENVLVT---ANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
+ HRDLK EN+L T N +KI DFGFAR ++ D L +T C +L YAAPE+L
Sbjct: 540 VVHRDLKPENLLFTDENDNLEIKIIDFGFAR-LKPPDNQPL-KTPCFTLHYAAPELLNQN 597
Query: 203 PYMPKLADMWSIGVILYTMLNKALPFNE-------TSVKKLYEKQVMRKWRFRTTVVNQL 255
Y + D+WS+GVILYTML+ +PF TS ++ +K + F +
Sbjct: 598 GY-DESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNV 656
Query: 256 STECKEQVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLL 303
S E K+ + L+ +P R S + W+ S+L+ + +L
Sbjct: 657 SQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDIL 704
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 123 bits (297), Expect = 8e-28
Identities = 74/233 (31%), Positives = 125/233 (53%), Gaps = 9/233 (3%)
Query: 19 LQEKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDV 78
+ EK +LE +IGEGS+ +VYK ++A K I L L RE+++
Sbjct: 17 VMEKYHVLE-MIGEGSFGRVYKGRRKYSA---QVVALKFIPKLGRSEKELRN-LQREIEI 71
Query: 79 LIRINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGL 138
+ + HP+IVH+ + F+ + + +AE G+L L +G +PE+Q + Q++S L
Sbjct: 72 MRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSAL 130
Query: 139 QYIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEV 198
Y+H+ I HRD+K +N+L+ +K+ DFGFAR ++ + G+ Y +PE+
Sbjct: 131 YYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFAR--AMSTNTMVLTSIKGTPLYMSPEL 188
Query: 199 LKGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
++ PY AD+WS+G ILY + PF TS+ +L + R+ +T+
Sbjct: 189 VEERPY-DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTI 240
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 123 bits (296), Expect = 1e-27
Identities = 73/268 (27%), Positives = 137/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A + E+ H I+A KV+ ++ ++ L L RE+++ +
Sbjct: 9 FEIGRPLGKGKFGNVYLAR--LKES-HFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 65
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F + ++ L +A G+L L ++ + E ++ + ++ L Y H
Sbjct: 66 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 125
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ VKI DFG++ + R +T CG+L Y PE+++G
Sbjct: 126 KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRR----KTMCGTLDYLPPEMIEGRT 181
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y K+ D+W IGV+ Y +L PF S + Y + + RF + + ++ +
Sbjct: 182 YDEKV-DLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLS----MPLGARDLI 236
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ +P R + + W+ SR
Sbjct: 237 SRLLRYQPLERLPLAQILKHPWVQAHSR 264
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 123 bits (296), Expect = 1e-27
Identities = 65/207 (31%), Positives = 116/207 (56%), Gaps = 5/207 (2%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + +GEG+Y +V A + V E +A K++D +A + + +E+ + +NH
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTE---EAVAVKIVDMKRAVD--CPENIKKEICINKMLNHE 65
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++V + ++FL + G+L D + + +PE ++ + Q+++G+ Y+H +
Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIG 125
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRD+K EN+L+ N+KI+DFG A R +R+ L CG+L Y APE+LK +
Sbjct: 126 ITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFH 185
Query: 206 PKLADMWSIGVILYTMLNKALPFNETS 232
+ D+WS G++L ML LP+++ S
Sbjct: 186 AEPVDVWSCGIVLTAMLAGELPWDQPS 212
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 123 bits (296), Expect = 1e-27
Identities = 65/207 (31%), Positives = 116/207 (56%), Gaps = 5/207 (2%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + +GEG+Y +V A + V E +A K++D +A + + +E+ + +NH
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTE---EAVAVKIVDMKRAVD--CPENIKKEICINKMLNHE 65
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++V + ++FL + G+L D + + +PE ++ + Q+++G+ Y+H +
Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIG 125
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRD+K EN+L+ N+KI+DFG A R +R+ L CG+L Y APE+LK +
Sbjct: 126 ITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFH 185
Query: 206 PKLADMWSIGVILYTMLNKALPFNETS 232
+ D+WS G++L ML LP+++ S
Sbjct: 186 AEPVDVWSCGIVLTAMLAGELPWDQPS 212
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 123 bits (296), Expect = 1e-27
Identities = 73/268 (27%), Positives = 137/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A + E+ H I+A KV+ ++ ++ L L RE+++ +
Sbjct: 40 FEIGRPLGKGKFGNVYLAR--LKES-HFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 96
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F + ++ L +A G+L L ++ + E ++ + ++ L Y H
Sbjct: 97 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 156
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ VKI DFG++ + R +T CG+L Y PE+++G
Sbjct: 157 KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRR----KTMCGTLDYLPPEMIEGRT 212
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y K+ D+W IGV+ Y +L PF S + Y + + RF + + ++ +
Sbjct: 213 YDEKV-DLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLS----MPLGARDLI 267
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ +P R + + W+ SR
Sbjct: 268 SRLLRYQPLERLPLAQILKHPWVQAHSR 295
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 123 bits (296), Expect = 1e-27
Identities = 73/268 (27%), Positives = 137/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A + E+ H I+A KV+ ++ ++ L L RE+++ +
Sbjct: 24 FEIGRPLGKGKFGNVYLAR--LKES-HFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 80
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F + ++ L +A G+L L ++ + E ++ + ++ L Y H
Sbjct: 81 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 140
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ VKI DFG++ + R +T CG+L Y PE+++G
Sbjct: 141 KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRR----KTMCGTLDYLPPEMIEGRT 196
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y K+ D+W IGV+ Y +L PF S + Y + + RF + + ++ +
Sbjct: 197 YDEKV-DLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLS----MPLGARDLI 251
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ +P R + + W+ SR
Sbjct: 252 SRLLRYQPLERLPLAQILKHPWVQAHSR 279
>AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 123 bits (296), Expect = 1e-27
Identities = 66/206 (32%), Positives = 112/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + A KV+ A RD + + R D+L+ +
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMER--DILVEV 130
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GD+ L++ E + ++ ++ L ++H
Sbjct: 131 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH 190
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
+ I +RDLK EN+L+ ++K+TDFG ++ D++ + ++CG++ Y APEV+
Sbjct: 191 QLGIVYRDLKPENILLDEIGHIKLTDFGLSK--ESVDQEKKAYSFCGTVEYMAPEVVNRR 248
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 249 GH-SQSADWWSYGVLMFEMLTGTLPF 273
Score = 100 bits (239), Expect = 9e-21
Identities = 75/270 (27%), Positives = 134/270 (49%), Gaps = 23/270 (8%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN-H 84
L++ IG GSY+ + H T + A K+ID +K RD E+++L+R H
Sbjct: 428 LKEDIGVGSYSVCKRCIHA---TTNMEFAVKIIDKSK--RDP-----SEEIEILMRYGQH 477
Query: 85 PHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTM 144
P+I+ + ++F ++ + G+LLD + + E ++ + I + Y+H
Sbjct: 478 PNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQ 537
Query: 145 NIAHRDLKCENVLV----TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200
+ HRDLK N+L + +++I DFGFA+ +R + +L T C + ++ APEVL
Sbjct: 538 GVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLL--TPCYTANFVAPEVLM 595
Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPF----NETSVKKLYEKQVMRKWRFRTTVVNQLS 256
Y D+WS+GV+ YTML PF N+T +++ + K+ + +S
Sbjct: 596 QQGY-DAACDIWSLGVLFYTMLAGYTPFANGPNDTP-EEILLRIGNGKFSLSGGNWDNIS 653
Query: 257 TECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
K+ ++ ++ +P R TA + +WI
Sbjct: 654 DGAKDLLSHMLHMDPHQRYTAEQILKHSWI 683
>AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 123 bits (296), Expect = 1e-27
Identities = 66/206 (32%), Positives = 112/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + A KV+ A RD + + R D+L+ +
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMER--DILVEV 130
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GD+ L++ E + ++ ++ L ++H
Sbjct: 131 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH 190
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
+ I +RDLK EN+L+ ++K+TDFG ++ D++ + ++CG++ Y APEV+
Sbjct: 191 QLGIVYRDLKPENILLDEIGHIKLTDFGLSK--ESVDQEKKAYSFCGTVEYMAPEVVNRR 248
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 249 GH-SQSADWWSYGVLMFEMLTGTLPF 273
Score = 100 bits (239), Expect = 9e-21
Identities = 75/270 (27%), Positives = 134/270 (49%), Gaps = 23/270 (8%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN-H 84
L++ IG GSY+ + H T + A K+ID +K RD E+++L+R H
Sbjct: 428 LKEDIGVGSYSVCKRCIHA---TTNMEFAVKIIDKSK--RDP-----SEEIEILMRYGQH 477
Query: 85 PHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTM 144
P+I+ + ++F ++ + G+LLD + + E ++ + I + Y+H
Sbjct: 478 PNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQ 537
Query: 145 NIAHRDLKCENVLV----TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200
+ HRDLK N+L + +++I DFGFA+ +R + +L T C + ++ APEVL
Sbjct: 538 GVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLL--TPCYTANFVAPEVLM 595
Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPF----NETSVKKLYEKQVMRKWRFRTTVVNQLS 256
Y D+WS+GV+ YTML PF N+T +++ + K+ + +S
Sbjct: 596 QQGY-DAACDIWSLGVLFYTMLAGYTPFANGPNDTP-EEILLRIGNGKFSLSGGNWDNIS 653
Query: 257 TECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
K+ ++ ++ +P R TA + +WI
Sbjct: 654 DGAKDLLSHMLHMDPHQRYTAEQILKHSWI 683
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 123 bits (296), Expect = 1e-27
Identities = 65/207 (31%), Positives = 116/207 (56%), Gaps = 5/207 (2%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + +GEG+Y +V A + V E +A K++D +A + + +E+ + +NH
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTE---EAVAVKIVDMKRAVD--CPENIKKEICINKMLNHE 65
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++V + ++FL + G+L D + + +PE ++ + Q+++G+ Y+H +
Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIG 125
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRD+K EN+L+ N+KI+DFG A R +R+ L CG+L Y APE+LK +
Sbjct: 126 ITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFH 185
Query: 206 PKLADMWSIGVILYTMLNKALPFNETS 232
+ D+WS G++L ML LP+++ S
Sbjct: 186 AEPVDVWSCGIVLTAMLAGELPWDQPS 212
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 123 bits (296), Expect = 1e-27
Identities = 74/231 (32%), Positives = 124/231 (53%), Gaps = 9/231 (3%)
Query: 21 EKGFILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLI 80
EK +LE +IGEGS+ +VYK ++A K I L L RE++++
Sbjct: 2 EKYHVLE-MIGEGSFGRVYKGRRKYSA---QVVALKFIPKLGRSEKELRN-LQREIEIMR 56
Query: 81 RINHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQY 140
+ HP+IVH+ + F+ + + +AE G+L L +G +PE+Q + Q++S L Y
Sbjct: 57 GLRHPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYY 115
Query: 141 IHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200
+H+ I HRD+K +N+L+ +K+ DFGFAR ++ + G+ Y +PE+++
Sbjct: 116 LHSHRILHRDMKPQNILLAKGGGIKLCDFGFAR--AMSTNTMVLTSIKGTPLYMSPELVE 173
Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTV 251
PY AD+WS+G ILY + PF TS+ +L + R+ +T+
Sbjct: 174 ERPY-DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTI 223
>AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase
protein.
Length = 745
Score = 123 bits (296), Expect = 1e-27
Identities = 66/206 (32%), Positives = 112/206 (54%), Gaps = 6/206 (2%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAP-RDYLTKFLPRELDVLIRI 82
F L KV+G+GS+ KV+ + A KV+ A RD + + R D+L+ +
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMER--DILVEV 130
Query: 83 NHPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIH 142
NHP IV + FQ K ++ L F GD+ L++ E + ++ ++ L ++H
Sbjct: 131 NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLH 190
Query: 143 TMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGV 202
+ I +RDLK EN+L+ ++K+TDFG ++ D++ + ++CG++ Y APEV+
Sbjct: 191 QLGIVYRDLKPENILLDEIGHIKLTDFGLSK--ESVDQEKKAYSFCGTVEYMAPEVVNRR 248
Query: 203 PYMPKLADMWSIGVILYTMLNKALPF 228
+ + AD WS GV+++ ML LPF
Sbjct: 249 GH-SQSADWWSYGVLMFEMLTGTLPF 273
Score = 100 bits (239), Expect = 9e-21
Identities = 75/270 (27%), Positives = 134/270 (49%), Gaps = 23/270 (8%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN-H 84
L++ IG GSY+ + H T + A K+ID +K RD E+++L+R H
Sbjct: 428 LKEDIGVGSYSVCKRCIHA---TTNMEFAVKIIDKSK--RDP-----SEEIEILMRYGQH 477
Query: 85 PHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTM 144
P+I+ + ++F ++ + G+LLD + + E ++ + I + Y+H
Sbjct: 478 PNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQ 537
Query: 145 NIAHRDLKCENVLV----TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK 200
+ HRDLK N+L + +++I DFGFA+ +R + +L T C + ++ APEVL
Sbjct: 538 GVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLL--TPCYTANFVAPEVLM 595
Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPF----NETSVKKLYEKQVMRKWRFRTTVVNQLS 256
Y D+WS+GV+ YTML PF N+T +++ + K+ + +S
Sbjct: 596 QQGY-DAACDIWSLGVLFYTMLAGYTPFANGPNDTP-EEILLRIGNGKFSLSGGNWDNIS 653
Query: 257 TECKEQVTQLMEPEPKSRPTASAVFNGTWI 286
K+ ++ ++ +P R TA + +WI
Sbjct: 654 DGAKDLLSHMLHMDPHQRYTAEQILKHSWI 683
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 123 bits (296), Expect = 1e-27
Identities = 65/207 (31%), Positives = 116/207 (56%), Gaps = 5/207 (2%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + +GEG+Y +V A + V E +A K++D +A + + +E+ + +NH
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTE---EAVAVKIVDMKRAVD--CPENIKKEICINKMLNHE 65
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++V + ++FL + G+L D + + +PE ++ + Q+++G+ Y+H +
Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIG 125
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRD+K EN+L+ N+KI+DFG A R +R+ L CG+L Y APE+LK +
Sbjct: 126 ITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFH 185
Query: 206 PKLADMWSIGVILYTMLNKALPFNETS 232
+ D+WS G++L ML LP+++ S
Sbjct: 186 AEPVDVWSCGIVLTAMLAGELPWDQPS 212
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 123 bits (296), Expect = 1e-27
Identities = 65/207 (31%), Positives = 116/207 (56%), Gaps = 5/207 (2%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + +GEG+Y +V A + V E +A K++D +A + + +E+ + +NH
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTE---EAVAVKIVDMKRAVD--CPENIKKEICINKMLNHE 65
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++V + ++FL + G+L D + + +PE ++ + Q+++G+ Y+H +
Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIG 125
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRD+K EN+L+ N+KI+DFG A R +R+ L CG+L Y APE+LK +
Sbjct: 126 ITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFH 185
Query: 206 PKLADMWSIGVILYTMLNKALPFNETS 232
+ D+WS G++L ML LP+++ S
Sbjct: 186 AEPVDVWSCGIVLTAMLAGELPWDQPS 212
>AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein
kinase 3 protein.
Length = 489
Score = 123 bits (296), Expect = 1e-27
Identities = 89/339 (26%), Positives = 163/339 (48%), Gaps = 20/339 (5%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
+++ ++IGEG + + H E+ + + A K I K+ + T+ +E +L ++
Sbjct: 4 YMVLRMIGEGFFGRALLVQH---ESSNQMFAMKEIRLPKSFSN--TQNSRKEAVLLAKMK 58
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGA--IPENQSRLWMRQIISGLQYI 141
HP+IV F+ +I + + + GDL+ + Q PE+ W Q+ G+ +I
Sbjct: 59 HPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHI 118
Query: 142 HTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKG 201
H + HRD+K +N+ +T N VK+ DFG AR + + + TY G+ Y PE+ +
Sbjct: 119 HKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLL--SNPMAFACTYVGTPYYVPPEIWEN 176
Query: 202 VPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKE 261
+PY K +D+WS+G ILY + PF S K L K + + + S E +
Sbjct: 177 LPYNNK-SDIWSLGCILYELCTLKHPFQANSWKNLILKVCQ---GCISPLPSHYSYELQF 232
Query: 262 QVTQLMEPEPKSRPTASAVFNGTWIGMDSRLAKLTFLEESLLKQAHEESQKRDNSTEEDS 321
V Q+ + P RP+A+ + + G+ +RL + E +++ E ++ NS
Sbjct: 233 LVKQMFKRNPSHRPSATTLLSR---GIVARLVQKCLPPEIIMEYGEEVLEEIKNSKHNTP 289
Query: 322 EVERIAELRRKGRGKEGLKVLKNVDANYAKSLYLFENKD 360
++ E RKG + L++++ N +S N++
Sbjct: 290 RKKQEEEQDRKGSHTD----LESINENLVESALRRVNRE 324
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 123 bits (296), Expect = 1e-27
Identities = 65/207 (31%), Positives = 116/207 (56%), Gaps = 5/207 (2%)
Query: 26 LEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHP 85
L + +GEG+Y +V A + V E +A K++D +A + + +E+ + +NH
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTE---EAVAVKIVDMKRAVD--CPENIKKEICINKMLNHE 65
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
++V + ++FL + G+L D + + +PE ++ + Q+++G+ Y+H +
Sbjct: 66 NVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIG 125
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
I HRD+K EN+L+ N+KI+DFG A R +R+ L CG+L Y APE+LK +
Sbjct: 126 ITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFH 185
Query: 206 PKLADMWSIGVILYTMLNKALPFNETS 232
+ D+WS G++L ML LP+++ S
Sbjct: 186 AEPVDVWSCGIVLTAMLAGELPWDQPS 212
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 123 bits (296), Expect = 1e-27
Identities = 73/268 (27%), Positives = 137/268 (51%), Gaps = 12/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A + E+ H I+A KV+ ++ ++ L L RE+++ +
Sbjct: 43 FEIGRPLGKGKFGNVYLAR--LKES-HFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 99
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F + ++ L +A G+L L ++ + E ++ + ++ L Y H
Sbjct: 100 HPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHD 159
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ VKI DFG++ + R +T CG+L Y PE+++G
Sbjct: 160 KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRR----KTMCGTLDYLPPEMIEGRT 215
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
Y K+ D+W IGV+ Y +L PF S + Y + + RF + + ++ +
Sbjct: 216 YDEKV-DLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLS----MPLGARDLI 270
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ +P R + + W+ SR
Sbjct: 271 SRLLRYQPLERLPLAQILKHPWVQAHSR 298
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 123 bits (296), Expect = 1e-27
Identities = 74/268 (27%), Positives = 137/268 (51%), Gaps = 13/268 (4%)
Query: 24 FILEKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRIN 83
F + + +G+G + VY A ++ H I+A KV+ ++ ++ + L RE+++ ++
Sbjct: 77 FEIGRPLGKGKFGNVYLAR---EKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLH 133
Query: 84 HPHIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHT 143
HP+I+ + N F R + ++ L +A G+L L ++ E ++ M ++ L Y H
Sbjct: 134 HPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHG 193
Query: 144 MNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVP 203
+ HRD+K EN+L+ +KI DFG++ + R +T CG+L Y PE+++G
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHATSLRR----KTMCGTLDYLPPEMIEGRI 249
Query: 204 YMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQV 263
K+ D+W IGV+ Y +L PF S + Y + V +F +V T ++ +
Sbjct: 250 DNEKV-DLWCIGVLCYELL-VGNPFESASHNETYRRIVKVDLKFPASV----PTGAQDLI 303
Query: 264 TQLMEPEPKSRPTASAVFNGTWIGMDSR 291
++L+ P R + V W+ +SR
Sbjct: 304 SKLLRHNPSERLPLAQVSAHPWVRANSR 331
>BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein.
Length = 390
Score = 122 bits (295), Expect = 1e-27
Identities = 76/263 (28%), Positives = 141/263 (53%), Gaps = 15/263 (5%)
Query: 27 EKVIGEGSYAKVYKATHMVDETRHSIMACKVIDTAK-APRDY--LTKFLPRELDVLIRIN 83
++++G G + V + H +++ V +P + L + +E+D+L +++
Sbjct: 23 KEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKVS 82
Query: 84 -HPHIVHVSNIFQRRAKYF-IFLRF--AENGDLLDFLTQNGAIPENQSRLWMRQIISGLQ 139
HP+I+ + + ++ +F +F F + G+L D+LT+ + E ++R MR ++ +
Sbjct: 83 GHPNIIQLKDTYETNTFFFLVFDLFHRMKRGELFDYLTEKATLSEKETRKIMRALLEVIC 142
Query: 140 YIHTMNIAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVL 199
+H +NI HRDLK EN+L+ N N+K+TDFGF+ + +R L E CG+ SY APE++
Sbjct: 143 TLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER--LREV-CGTPSYLAPEII 199
Query: 200 -----KGVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQ 254
+ P K DMWS GVI+YT+L + PF + + ++F + +
Sbjct: 200 ECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDD 259
Query: 255 LSTECKEQVTQLMEPEPKSRPTA 277
S K+ V++ + +P++R TA
Sbjct: 260 YSDTVKDLVSRFLVVQPQNRYTA 282
>Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamma
subunit protein.
Length = 406
Score = 122 bits (294), Expect = 2e-27
Identities = 72/257 (28%), Positives = 137/257 (53%), Gaps = 11/257 (4%)
Query: 29 VIGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPR--DYLTKFLPRELDVLIRI-NHP 85
VIG G + V + H ++ +V +P + + + RE +L ++ HP
Sbjct: 29 VIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHP 88
Query: 86 HIVHVSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMN 145
HI+ + + ++ + F+ G+L D+LT+ A+ E ++R MR ++ + ++H N
Sbjct: 89 HIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANN 148
Query: 146 IAHRDLKCENVLVTANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLK----- 200
I HRDLK EN+L+ N ++++DFGF+ ++ ++ L E CG+ Y APE+LK
Sbjct: 149 IVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEK--LRE-LCGTPGYLAPEILKCSMDE 205
Query: 201 GVPYMPKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECK 260
P K D+W+ GVIL+T+L + PF + + +++F + + S+ K
Sbjct: 206 THPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVK 265
Query: 261 EQVTQLMEPEPKSRPTA 277
+ +++L++ +P++R TA
Sbjct: 266 DLISRLLQVDPEARLTA 282
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 122 bits (294), Expect = 2e-27
Identities = 70/261 (26%), Positives = 127/261 (48%), Gaps = 8/261 (3%)
Query: 30 IGEGSYAKVYKATHMVDETRHSIMACKVIDTAKAPRDYLTKFLPRELDVLIRINHPHIVH 89
+G G +A V K +++ K T + R + + RE+ +L I HP+++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVIT 78
Query: 90 VSNIFQRRAKYFIFLRFAENGDLLDFLTQNGAIPENQSRLWMRQIISGLQYIHTMNIAHR 149
+ +++ + + L G+L DFL + ++ E ++ +++QI++G+ Y+H++ IAH
Sbjct: 79 LHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHF 138
Query: 150 DLKCENVLV----TANYNVKITDFGFARNVRQRDRDVLSETYCGSLSYAAPEVLKGVPYM 205
DLK EN+++ +KI DFG A + D + G+ + APE++ P +
Sbjct: 139 DLKPENIMLLDRNVPKPRIKIIDFGLAHKI---DFGNEFKNIFGTPEFVAPEIVNYEP-L 194
Query: 206 PKLADMWSIGVILYTMLNKALPFNETSVKKLYEKQVMRKWRFRTTVVNQLSTECKEQVTQ 265
ADMWSIGVI Y +L+ A PF + ++ + F + S K+ + +
Sbjct: 195 GLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRR 254
Query: 266 LMEPEPKSRPTASAVFNGTWI 286
L+ +PK R T WI
Sbjct: 255 LLVKDPKKRMTIQDSLQHPWI 275
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.134 0.387
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 49,292,462
Number of Sequences: 224733
Number of extensions: 1933650
Number of successful extensions: 16206
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2469
Number of HSP's successfully gapped in prelim test: 359
Number of HSP's that attempted gapping in prelim test: 9046
Number of HSP's gapped (non-prelim): 3333
length of query: 360
length of database: 73,234,838
effective HSP length: 91
effective length of query: 269
effective length of database: 52,784,135
effective search space: 14198932315
effective search space used: 14198932315
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
- SilkBase 1999-2023 -