BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001012-TA|BGIBMGA001012-PA|IPR011009|Protein kinase-like, IPR000719|Protein kinase, IPR008271|Serine/threonine protein kinase, active site, IPR001245|Tyrosine protein kinase, IPR002290|Serine/threonine protein kinase (655 letters) Database: spombe 5004 sequences; 2,362,478 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosac... 154 3e-38 SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |S... 150 5e-37 SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schiz... 144 3e-35 SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Sch... 142 2e-34 SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|c... 135 2e-32 SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |S... 134 3e-32 SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |S... 133 6e-32 SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1... 128 3e-30 SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosa... 127 4e-30 SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizos... 126 1e-29 SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizo... 124 3e-29 SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase... 122 2e-28 SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosac... 121 3e-28 SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccha... 117 4e-27 SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase P... 116 8e-27 SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosacc... 116 8e-27 SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosa... 116 1e-26 SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase ... 114 4e-26 SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalyt... 113 6e-26 SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces ... 111 2e-25 SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizo... 111 4e-25 SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosacchar... 111 4e-25 SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosac... 109 9e-25 SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizos... 109 2e-24 SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharom... 108 2e-24 SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosa... 108 3e-24 SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosacc... 106 1e-23 SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc... 105 3e-23 SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizo... 102 1e-22 SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosa... 102 2e-22 SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomy... 98 3e-21 SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizo... 95 4e-20 SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|S... 92 2e-19 SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces po... 91 6e-19 SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2... 90 8e-19 SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schiz... 90 1e-18 SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces... 90 1e-18 SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizo... 89 2e-18 SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizos... 89 2e-18 SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|... 89 2e-18 SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1||... 88 4e-18 SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Sch... 87 5e-18 SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosacch... 87 1e-17 SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|ch... 85 2e-17 SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosacch... 85 2e-17 SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizo... 85 4e-17 SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosacchar... 84 5e-17 SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe... 84 7e-17 SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schiz... 83 9e-17 SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosa... 81 4e-16 SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomy... 81 5e-16 SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomy... 81 6e-16 SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizos... 81 6e-16 SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Sc... 81 6e-16 SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schi... 80 8e-16 SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Pp... 79 3e-15 SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schiz... 78 3e-15 SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosa... 78 3e-15 SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosac... 78 4e-15 SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizo... 77 1e-14 SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Sch... 76 1e-14 SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizos... 76 2e-14 SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosa... 75 4e-14 SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Sch... 74 5e-14 SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizos... 74 7e-14 SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizos... 74 7e-14 SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccha... 73 2e-13 SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyc... 73 2e-13 SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase S... 72 2e-13 SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccha... 72 2e-13 SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating ... 71 7e-13 SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizos... 70 1e-12 SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase ki... 69 2e-12 SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosac... 67 8e-12 SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizo... 66 2e-11 SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosac... 66 2e-11 SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity prote... 66 2e-11 SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gc... 64 6e-11 SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizos... 63 1e-10 SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyc... 63 1e-10 SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schi... 59 2e-09 SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |... 57 9e-09 SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosacchar... 56 2e-08 SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosa... 51 4e-07 SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein k... 48 3e-06 SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Sch... 48 5e-06 SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizos... 46 2e-05 SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schi... 46 2e-05 SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk... 45 3e-05 SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schiz... 43 1e-04 SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizo... 42 2e-04 SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizo... 41 6e-04 SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizos... 39 0.003 SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizos... 38 0.006 SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosa... 37 0.010 SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosa... 35 0.031 SPAC27E2.09 |mak2|phk1|histidine kinase Mak2 |Schizosaccharomyce... 35 0.031 SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosac... 35 0.041 SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosa... 33 0.13 SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosacchar... 32 0.22 SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizos... 32 0.29 SPCC74.06 |mak3|phk2|histidine kinase Mak3 |Schizosaccharomyces ... 31 0.50 SPAC20H4.05c |||adducin|Schizosaccharomyces pombe|chr 1|||Manual 31 0.67 SPCC736.10c |mrps8||mitochondrial ribosomal protein subunit S8|S... 30 0.88 SPBC29A3.14c |trt1||telomerase reverse transcriptase 1 protein T... 30 1.2 SPBC336.14c |ppk26||serine/threonine protein kinase Ppk26|Schizo... 29 1.5 SPCC24B10.22 ||SPCPB16A4.01|mitochondrial DNA polymerase gamma c... 29 1.5 SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces p... 29 1.5 SPAC144.05 |||ATP-dependent DNA helicase|Schizosaccharomyces pom... 29 2.0 SPBC19G7.13 |trf1||telomeric DNA binding factor Trf1|Schizosacch... 29 2.7 SPBC691.03c |apl3||AP-2 adaptor complex subunit Alp3 |Schizosacc... 28 3.6 SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces po... 28 3.6 SPAC22A12.03c |csn4||COP9/signalosome complex subunit Csn4 |Schi... 28 4.7 SPBC428.08c |clr4||histone H3 methyltransferase Clr4|Schizosacch... 27 6.2 SPAC7D4.04 |taf1||Taz1 interacting factor 1|Schizosaccharomyces ... 27 6.2 SPAP27G11.07c |||serine/threonine protein kinase |Schizosaccharo... 27 6.2 SPAC22F3.12c |rgs1||regulator of G-protein signaling Rgs1|Schizo... 27 8.2 SPAC3A11.12c |rpt5|pam2, tbp1|19S proteasome regulatory subunit ... 27 8.2 >SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosaccharomyces pombe|chr 3|||Manual Length = 460 Score = 154 bits (374), Expect = 3e-38 Identities = 93/284 (32%), Positives = 149/284 (52%), Gaps = 16/284 (5%) Query: 9 SEENTLLTKG--YKLTKFVGEGAYAKVYLTEY--SSKEDSHKSTLACKIIETAKAPKDFV 64 S++N + ++ Y++ + +G G +A V L S K + K KI+ T+ + Sbjct: 155 SQKNMIKSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKR--A 212 Query: 65 VKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQAR 124 + REID+L L+HP ++ H IF+ + +I M Y E GDL+ +++ NG + E + Sbjct: 213 TEMFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCK 272 Query: 125 VWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETY 184 +QL L +LH+ + HRDIK EN+L+T +F++K+SDFG ++ ET+ Sbjct: 273 PLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVI---HGTGTFLETF 329 Query: 185 CGSMSYAAPEILRGK------PYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQM 238 CG+M Y APE+L+ K Y K D+WSLG VL+VML S+PF + K E Sbjct: 330 CGTMGYLAPEVLKSKNVNLDGGYDDK-VDIWSLGCVLYVMLTASIPFASSSQAKCIELIS 388 Query: 239 GKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282 Y + + +S E ++ +LE +P R S + L W Sbjct: 389 KGAYPIEPLLENEISEEGIDLINRMLEINPEKRISESEALQHPW 432 Score = 134 bits (324), Expect = 4e-32 Identities = 82/262 (31%), Positives = 134/262 (51%), Gaps = 11/262 (4%) Query: 356 KVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEF 415 K++ TS+ R + REI++L L HP +V H IF+ + FI M Y+E GDL++F Sbjct: 202 KILLTSSEKR--ATEMFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDF 259 Query: 416 VLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMC 475 ++ G++ E + +QL + ++H+ + HRDIK EN+L+T + ++K+SDFG A++ Sbjct: 260 LIANGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVI 319 Query: 476 VDKKLNEIRSETFCGSLSYTAPEILQGTPY-----LPKPTDVWSLGIVVYVMLNRAMPFE 530 ETFCG++ Y APE+L+ D+WSLG V+YVML ++PF Sbjct: 320 HG---TGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFA 376 Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590 + + + + IS+ LI MLE N + R+ + + W Sbjct: 377 SSSQAKCIELISKGAYPIEPLLENEISEEGIDLINRMLEINPEKRISESEALQHPWFYTV 436 Query: 591 SRLLEWTPQETLAYKKAREEKN 612 S TP + + +A E+ N Sbjct: 437 STHEHRTPPSSSEH-EATEQLN 457 >SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 891 Score = 150 bits (364), Expect = 5e-37 Identities = 69/214 (32%), Positives = 123/214 (57%), Gaps = 8/214 (3%) Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433 RE + L HP++ ++ Y++ +++ G +L++++ G ++E QAR + RQ Sbjct: 190 REAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQARKFVRQ 249 Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493 + A+ Y+H+ + HRD+K EN+L++ ++K+ DFG + + + R TFCGSL Sbjct: 250 IGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNL----YRRQSRLRTFCGSLY 305 Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553 + APE+L PY+ DVWS GIV+YV++ +PF+D+++ LH A+I K Y Sbjct: 306 FAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALH-AKIKKG---TVEYP 361 Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587 +S +CK L+ ML + R + +++N W+ Sbjct: 362 SYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWM 395 Score = 149 bits (361), Expect = 1e-36 Identities = 74/238 (31%), Positives = 128/238 (53%), Gaps = 9/238 (3%) Query: 46 KSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTEN 105 K+ + + + A++ K+ ++ + RE + L HP++ ++ + YY+ + + Sbjct: 167 KAAASAEATKAAQSEKNKEIRTV-REAALSTLLRHPYICEARDVYITNSHYYMVFEFVDG 225 Query: 106 GDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDF 165 G +L YI+ +G + E QAR + RQ+ L YLH+ + HRD+K EN+L++ ++K+ DF Sbjct: 226 GQMLDYIISHGKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDF 285 Query: 166 GFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 G S T+CGS+ +AAPE+L +PY D+WS G+VL+V++ +PF Sbjct: 286 GLSNLYRRQSR----LRTFCGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPF 341 Query: 226 DDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283 DD M L+ K + S LS +CK ++ +L DP R + VL+ W+ Sbjct: 342 DDQNMSALH----AKIKKGTVEYPSYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWM 395 >SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schizosaccharomyces pombe|chr 3|||Manual Length = 576 Score = 144 bits (350), Expect = 3e-35 Identities = 83/265 (31%), Positives = 141/265 (53%), Gaps = 15/265 (5%) Query: 19 YKLTKFVGEGAYAKVYL-TEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVR 77 Y + + +GEG++ KV L T Y +++ +A K I K + + REI L Sbjct: 34 YIIRETLGEGSFGKVKLATHYKTQQK-----VALKFISRQLLKKSDMHMRVEREISYLKL 88 Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137 L HPH+I ++ + T + + Y G+L YI++ ++E++ R + +Q+ ++Y Sbjct: 89 LRHPHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYC 147 Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197 H +I HRD+K EN+LL N NVK++DFG S + + +T CGS +YAAPE++ Sbjct: 148 HRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGN----FLKTSCGSPNYAAPEVIN 203 Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257 GK Y D+WS G+VL+VML +PFDD + L+++ Y + LS + Sbjct: 204 GKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVY----VMPDFLSPGAQ 259 Query: 258 TVVKHLLEPDPGLRHSATNVLDSEW 282 ++++ ++ DP R + + W Sbjct: 260 SLIRRMIVADPMQRITIQEIRRDPW 284 Score = 130 bits (315), Expect = 5e-31 Identities = 75/234 (32%), Positives = 122/234 (52%), Gaps = 9/234 (3%) Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412 +A K I + + + REI L L HPH++ + + + + Y G+L Sbjct: 60 VALKFISRQLLKKSDMHMRVEREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYAG-GEL 118 Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472 ++++++ + ED+ R + +Q+ AI+Y H +I HRD+K EN+LL N NVK++DFG + Sbjct: 119 FDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLS 178 Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532 + D +T CGS +Y APE++ G Y DVWS GIV+YVML +PF+D+ Sbjct: 179 NIMTDGNF----LKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDE 234 Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586 I L + ++N D +S + LI M+ + R+ I +I W Sbjct: 235 FIPNLFK-KVNSCVYVMP---DFLSPGAQSLIRRMIVADPMQRITIQEIRRDPW 284 >SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Schizosaccharomyces pombe|chr 2|||Manual Length = 423 Score = 142 bits (343), Expect = 2e-34 Identities = 82/211 (38%), Positives = 112/211 (53%), Gaps = 9/211 (4%) Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137 L HP++ V + YI Y G LL YIL G + E+ AR + QL L YL Sbjct: 107 LRHPNICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYL 166 Query: 138 HELEIAHRDIKCENVLLTANFN-VKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196 H+ I HRD+K ENVLLT + VKL DFG S F + D L TYCGS+ +AAPE+L Sbjct: 167 HKNFIVHRDLKIENVLLTQDSRQVKLIDFGLSNFYSKDD----LLRTYCGSLYFAAPELL 222 Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256 KPY D+WSLGVV++VM+ +PFDD + L+ + K F S +S +C Sbjct: 223 DAKPYIGPEVDVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEF----PSYISEDC 278 Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWIAMDS 287 +++ +L +P R S W+ +S Sbjct: 279 CSLIAAMLNVNPRKRCSLEQAAKFPWLKKNS 309 Score = 138 bits (335), Expect = 2e-33 Identities = 78/211 (36%), Positives = 112/211 (53%), Gaps = 9/211 (4%) Query: 382 LSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYM 441 L HP++ + +I Y+ G LLE++L RG + ED AR + QL A+ Y+ Sbjct: 107 LRHPNICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYL 166 Query: 442 HELEIAHRDIKCENVLLTAN-QNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEIL 500 H+ I HRD+K ENVLLT + + VKL DFG + L T+CGSL + APE+L Sbjct: 167 HKNFIVHRDLKIENVLLTQDSRQVKLIDFGLSNFYSKDDL----LRTYCGSLYFAAPELL 222 Query: 501 QGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNC 560 PY+ DVWSLG+V+YVM+ +PF+D + LH + +F S IS++C Sbjct: 223 DAKPYIGPEVDVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFPS----YISEDC 278 Query: 561 KRLIGLMLEPNHQNRLKIYDIVNSEWIAMDS 591 LI ML N + R + W+ +S Sbjct: 279 CSLIAAMLNVNPRKRCSLEQAAKFPWLKKNS 309 >SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|chr 1|||Manual Length = 683 Score = 135 bits (326), Expect = 2e-32 Identities = 78/269 (28%), Positives = 135/269 (50%), Gaps = 11/269 (4%) Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84 +GEG +A+ + + D++ + A K+I D L EI V ++HP+++ Sbjct: 47 IGEGGFARCFRVK-----DNYGNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQSMSHPNIV 101 Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144 F+ T Y+ + E+ L+ + K ++E + R Q+ L+Y+H+ + H Sbjct: 102 GFIDCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIH 161 Query: 145 RDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL-RGKPYCP 203 RD+K N++L + NVK+ DFG + ++ + + + T CG+ +Y APEIL K Sbjct: 162 RDLKLGNIMLDESNNVKIGDFGLAALLMDDEERKM---TICGTPNYIAPEILFNSKEGHS 218 Query: 204 KPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHL 263 DLWS GVV++ +L PF D ++ +Y + Y F S V +S E K ++ L Sbjct: 219 FEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVD--ISAEAKDLISSL 276 Query: 264 LEPDPGLRHSATNVLDSEWIAMDSRLTTL 292 L DP +R S +++D E+ +TL Sbjct: 277 LTHDPSIRPSIDDIVDHEFFHTGYMASTL 305 Score = 127 bits (306), Expect = 6e-30 Identities = 79/242 (32%), Positives = 129/242 (53%), Gaps = 6/242 (2%) Query: 346 KNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMR 405 K++ +I A KVI + D K L EI++ +SHP++V F+ ++ + Sbjct: 59 KDNYGNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQSMSHPNIVGFIDCFEDSTNIYLILE 118 Query: 406 YMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVK 465 E L+E + +R + E + R Q+ A++YMH+ + HRD+K N++L + NVK Sbjct: 119 LCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIHRDLKLGNIMLDESNNVK 178 Query: 466 LSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPK-PTDVWSLGIVVYVMLN 524 + DFG A + +D +E R T CG+ +Y APEIL + D+WS G+V+Y +L Sbjct: 179 IGDFGLAALLMD---DEERKMTICGTPNYIAPEILFNSKEGHSFEVDLWSAGVVMYALLI 235 Query: 525 RAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNS 584 PF+DK +K +++ ++ F S +D IS K LI +L + R I DIV+ Sbjct: 236 GKPPFQDKEVKTIYRKIKANSYSFPSN-VD-ISAEAKDLISSLLTHDPSIRPSIDDIVDH 293 Query: 585 EW 586 E+ Sbjct: 294 EF 295 >SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |Schizosaccharomyces pombe|chr 1|||Manual Length = 672 Score = 134 bits (325), Expect = 3e-32 Identities = 83/261 (31%), Positives = 138/261 (52%), Gaps = 18/261 (6%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y++ VGEG++ KVYL +H T K++ + K ++ L REI RL Sbjct: 31 YRIESVVGEGSFGKVYLA-------AHLLTNT-KVVLKSSCRKQAII--LAREIHHHRRL 80 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138 HP++ ++ + + + Y+ M Y NG+L ++ + + E QL +QYLH Sbjct: 81 LHPNITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMWQLCCAIQYLH 140 Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESD-NQPVLSETYCGSMSYAAPEILR 197 HRD+K EN+ L +NVKL DFGFSR +SD ++ T CG+++Y APE+++ Sbjct: 141 RQGCVHRDLKLENIFLDKAYNVKLGDFGFSR---DSDCSRRTFMNTRCGTVAYCAPELVQ 197 Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257 G Y + D+WSLG++++ +L +PFD+ + L EQ++ + + LS Sbjct: 198 GHKYIGECVDIWSLGIIMYALLIGRLPFDEDDV-SLTEQKIINEC---PQYPETLSKNSS 253 Query: 258 TVVKHLLEPDPGLRHSATNVL 278 +++K LL D LR S ++ Sbjct: 254 SLLKSLLCKDYRLRPSIDQII 274 Score = 122 bits (293), Expect = 2e-28 Identities = 68/212 (32%), Positives = 113/212 (53%), Gaps = 6/212 (2%) Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431 L REI +L HP++ + + + ++ M Y G+L ++V + + E Sbjct: 70 LAREIHHHRRLLHPNITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIM 129 Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491 QL AIQY+H HRD+K EN+ L NVKL DFGF+R + + T CG+ Sbjct: 130 WQLCCAIQYLHRQGCVHRDLKLENIFLDKAYNVKLGDFGFSRDSDCSRRTFM--NTRCGT 187 Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551 ++Y APE++QG Y+ + D+WSLGI++Y +L +PF++ + Q IN+ + Sbjct: 188 VAYCAPELVQGHKYIGECVDIWSLGIIMYALLIGRLPFDEDDVSLTEQKIINE----CPQ 243 Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKIYDIVN 583 Y +T+S N L+ +L +++ R I I++ Sbjct: 244 YPETLSKNSSSLLKSLLCKDYRLRPSIDQIIS 275 >SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 445 Score = 133 bits (322), Expect = 6e-32 Identities = 98/301 (32%), Positives = 159/301 (52%), Gaps = 36/301 (11%) Query: 23 KFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAK-APKDFVVKFLPREIDVLVRLNHP 81 + +G G ++++Y+ + +++ ACKII+ K + K F F E+ +L +L+HP Sbjct: 164 RLLGIGGFSRIYM----AMDNNTGGQYACKIIDKKKISTKRF---FEDHEMTILRKLDHP 216 Query: 82 HLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELE 141 ++I V+ + +T+++IF GDL SY+ K G V E Q+ GL+YLHE Sbjct: 217 NIIKVNMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQILQGLKYLHEQN 276 Query: 142 IAHRDIKCENVLLTAN----FNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEI-- 195 I HRD+K EN+L+ ++ F + L+DFG +R C++ + LS T+ G+ Y APEI Sbjct: 277 IIHRDLKLENILIASSSDTIFRIILTDFGVAR-CMQKGKR--LS-TFVGTPEYTAPEIQR 332 Query: 196 LRGKPYCP--------KPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSR 247 L+G+ K DLWSLGV++F++L+ + P +++ K+ FR Sbjct: 333 LKGRSQVEKENSSGYGKEVDLWSLGVIMFLLLSGNSPSFADGVKE-------KQVDFRDP 385 Query: 248 VASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAM-DSRLTTLNAVEAAALKRAKED 306 V +S + K ++ +LL+ +P R + L W A SRLT L E LK K Sbjct: 386 VWKSVSRQAKDLISNLLKTNPPDRFTVKQCLSHPWFARHSSRLTKL--YETRILKPLKHS 443 Query: 307 R 307 R Sbjct: 444 R 444 Score = 108 bits (260), Expect = 2e-24 Identities = 76/255 (29%), Positives = 125/255 (49%), Gaps = 27/255 (10%) Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLL 413 ACK+ID + F E+ +L KL HP+++ + + ++FIF + GDL Sbjct: 187 ACKIIDKKKISTK--RFFEDHEMTILRKLDHPNIIKVNMEYNSETQFFIFEEMVTGGDLF 244 Query: 414 EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQN----VKLSDF 469 ++ + G V E Q+ ++Y+HE I HRD+K EN+L+ ++ + + L+DF Sbjct: 245 SYLTKLGTVPEVTTLFIMFQILQGLKYLHEQNIIHRDLKLENILIASSSDTIFRIILTDF 304 Query: 470 GFARMCVDKKLNEIRSETFCGSLSYTAPEI--LQGTPYLP--------KPTDVWSLGIVV 519 G AR C+ K R TF G+ YTAPEI L+G + K D+WSLG+++ Sbjct: 305 GVAR-CMQKGK---RLSTFVGTPEYTAPEIQRLKGRSQVEKENSSGYGKEVDLWSLGVIM 360 Query: 520 YVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIY 579 +++L+ P +K+ K FR ++S K LI +L+ N +R + Sbjct: 361 FLLLSGNSPSFADGVKE-------KQVDFRDPVWKSVSRQAKDLISNLLKTNPPDRFTVK 413 Query: 580 DIVNSEWIAMDSRLL 594 ++ W A S L Sbjct: 414 QCLSHPWFARHSSRL 428 >SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1023 Score = 128 bits (308), Expect = 3e-30 Identities = 94/303 (31%), Positives = 145/303 (47%), Gaps = 21/303 (6%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDS--HKSTLACKIIETAKAPKDFVVKFLPREIDVLV 76 Y L + +G G + KV L K +S H+ST I ++ L RE+ +L Sbjct: 492 YILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNCQTSRLMREVAILK 551 Query: 77 RL--NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134 L NHPH++ + K + I + Y G+L YIL + ++ A QL G+ Sbjct: 552 GLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLISGV 611 Query: 135 QYLHELEIAHRDIKCENVLLTANFNVKLSDFGFS----RFCVESDN-----QPVLSETYC 185 YLH + HRD+K EN+LL N N+ ++DFGF+ F S++ +P L T C Sbjct: 612 AYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTFGHFNTLSEHSLPTEKPDLFSTSC 671 Query: 186 GSMSYAAPEILRGKP--YCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYR 243 GS YAAPE++ K Y D+WS GV+L+ ML +PFDD E + + YR Sbjct: 672 GSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPFDDDPHNPNGE-NVPRLYR 730 Query: 244 FRSRVASI----LSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMD-SRLTTLNAVEAA 298 + I + + ++K +L PDP R + +++ ++ S T N EA Sbjct: 731 YICSTPLIFPEFFKSKARDILKKILVPDPAKRVRMSAIMNHAYLRSHVSLFETYNDDEAT 790 Query: 299 ALK 301 +L+ Sbjct: 791 SLR 793 Score = 100 bits (239), Expect = 7e-22 Identities = 55/173 (31%), Positives = 93/173 (53%), Gaps = 13/173 (7%) Query: 372 LPREIEMLIKL--SHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARI 429 L RE+ +L L +HPH+V + ++ + I + Y+ G+L +++L R +++ A Sbjct: 543 LMREVAILKGLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVACR 602 Query: 430 WTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA------RMCVDKKLNEI 483 QL + Y+H + HRD+K EN+LL N+N+ ++DFGFA + L Sbjct: 603 LFAQLISGVAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTFGHFNTLSEHSLPTE 662 Query: 484 RSETF---CGSLSYTAPEIL--QGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531 + + F CGS Y APE++ + Y D+WS G+++Y ML +PF+D Sbjct: 663 KPDLFSTSCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLPFDD 715 >SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosaccharomyces pombe|chr 3|||Manual Length = 355 Score = 127 bits (307), Expect = 4e-30 Identities = 76/265 (28%), Positives = 139/265 (52%), Gaps = 13/265 (4%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 +++ K +G+G + +VYL +KE +A K + ++ + + K + REI++ L Sbjct: 89 FEIGKPLGKGKFGRVYL----AKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNL 144 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138 H +++ ++ F + + Y+ + + G+L ++ + SE A + Q+A L YLH Sbjct: 145 RHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLH 204 Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198 + + HRDIK EN+LL + +KLSDFG+S V + + T CG++ Y PE++ G Sbjct: 205 KKHVIHRDIKPENILLGIDGEIKLSDFGWS---VHAPSN--RRTTLCGTLDYLPPEMVEG 259 Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258 K + K DLWSLGV+ + L + PF+D +++ K ++ S + + + Sbjct: 260 KEHTEK-VDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAK---VDLKIPSFVPPDARD 315 Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283 ++ LL+ +P R S V+ WI Sbjct: 316 LISRLLQHNPEKRMSLEQVMRHPWI 340 Score = 124 bits (300), Expect = 3e-29 Identities = 76/253 (30%), Positives = 130/253 (51%), Gaps = 14/253 (5%) Query: 335 RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIF 394 RVYLA+ + I+A K + S + ++K + REIE+ L H +++ + F Sbjct: 102 RVYLAKEKKTG-----FIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKNILRLYGHF 156 Query: 395 QRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCE 454 + ++ + + RG+L + + + E+ A + Q+A A+ Y+H+ + HRDIK E Sbjct: 157 HDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHVIHRDIKPE 216 Query: 455 NVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWS 514 N+LL + +KLSDFG++ V N R T CG+L Y PE+++G + K D+WS Sbjct: 217 NILLGIDGEIKLSDFGWS---VHAPSN--RRTTLCGTLDYLPPEMVEGKEHTEK-VDLWS 270 Query: 515 LGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQN 574 LG++ Y L A PFED H A + K + + + + LI +L+ N + Sbjct: 271 LGVLTYEFLVGAPPFED---MSGHSATYKRIAKVDLKIPSFVPPDARDLISRLLQHNPEK 327 Query: 575 RLKIYDIVNSEWI 587 R+ + ++ WI Sbjct: 328 RMSLEQVMRHPWI 340 >SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizosaccharomyces pombe|chr 1|||Manual Length = 532 Score = 126 bits (303), Expect = 1e-29 Identities = 76/266 (28%), Positives = 132/266 (49%), Gaps = 13/266 (4%) Query: 21 LTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNH 80 L + +G+G AKV L ++ + +A K++ + K L RE+ +L +L+H Sbjct: 25 LGRTLGQGNLAKVKLGKHFQTNEK----VALKMVYNDELEDKDTWKRLQREVTILRQLHH 80 Query: 81 PHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHEL 140 P++I ++ +F R KY + + DL S ++K+ + E R RQ+ + Y H Sbjct: 81 PNIITLYQVF-RVPKYTVLALEYMDTDLHSMVVKHNRLDECTTRKIFRQIVHAIDYCHLH 139 Query: 141 EIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKP 200 +AHRD+K EN+LL + VKL+DFG S F ++ T CG+ YAAPE+++G+ Sbjct: 140 RVAHRDLKLENILLNKDLVVKLTDFGLSNFMLDGS----FLSTSCGTPHYAAPEVIQGRY 195 Query: 201 YCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVV 260 Y D+W G++L++ML PF+D + + + Y + S +S ++ Sbjct: 196 YDGCDVDVWGCGILLYLMLVGEFPFEDVTISNVLSRVCKGIY----TIPSFVSSSASDLI 251 Query: 261 KHLLEPDPGLRHSATNVLDSEWIAMD 286 + +L P R ++ W D Sbjct: 252 RQMLMVLPTSRIKVAEIMQHPWFIAD 277 Score = 118 bits (284), Expect = 3e-27 Identities = 77/236 (32%), Positives = 119/236 (50%), Gaps = 11/236 (4%) Query: 370 KFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIF-MRYMERGDLLEFVLQRGAVQEDQAR 428 K L RE+ +L +L HP+++ + +F R KY + + YM+ DL V++ + E R Sbjct: 66 KRLQREVTILRQLHHPNIITLYQVF-RVPKYTVLALEYMDT-DLHSMVVKHNRLDECTTR 123 Query: 429 IWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETF 488 RQ+ AI Y H +AHRD+K EN+LL + VKL+DFG + +D T Sbjct: 124 KIFRQIVHAIDYCHLHRVAHRDLKLENILLNKDLVVKLTDFGLSNFMLDGSF----LSTS 179 Query: 489 CGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKF 548 CG+ Y APE++QG Y DVW GI++Y+ML PFED I + + Sbjct: 180 CGTPHYAAPEVIQGRYYDGCDVDVWGCGILLYLMLVGEFPFEDVTISNVLSRVCKGIYTI 239 Query: 549 RSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLLEWTPQETLAY 604 S + SD +++ LM+ P +R+K+ +I+ W D P T ++ Sbjct: 240 PSFVSSSASDLIRQM--LMVLPT--SRIKVAEIMQHPWFIADLPTHSRLPSRTSSF 291 >SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizosaccharomyces pombe|chr 3|||Manual Length = 569 Score = 124 bits (300), Expect = 3e-29 Identities = 69/241 (28%), Positives = 123/241 (51%), Gaps = 8/241 (3%) Query: 8 PSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKF 67 P++ L ++L K VG+G++ KV K D+ + A K ++ A V Sbjct: 219 PNQSTPLTIDAFELLKVVGKGSFGKVMQVR---KRDTSR-IYALKTMKKAHIVSRSEVDH 274 Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127 E VL ++N+P ++ + FQ K Y+ + + G+L ++ + GC +A+ + Sbjct: 275 TLAERTVLAQVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYI 334 Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187 +L + L+ LHE + +RD+K EN+LL ++ L DFG + + ++ + T+CG+ Sbjct: 335 AELLVALECLHEFNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDR---TNTFCGT 391 Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSR 247 Y APE+L G Y K D W+LGV+L+ M+ PF D + ++Y + + RF Sbjct: 392 PEYLAPELLLGHGY-TKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDN 450 Query: 248 V 248 + Sbjct: 451 I 451 Score = 105 bits (253), Expect = 1e-23 Identities = 59/202 (29%), Positives = 110/202 (54%), Gaps = 8/202 (3%) Query: 375 EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQL 434 E +L ++++P +V FQ K ++ + ++ G+L + + G +A+ + +L Sbjct: 278 ERTVLAQVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAEL 337 Query: 435 ALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSY 494 +A++ +HE + +RD+K EN+LL ++ L DFG ++ + K R+ TFCG+ Y Sbjct: 338 LVALECLHEFNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAK---TDRTNTFCGTPEY 394 Query: 495 TAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYID 554 APE+L G Y K D W+LG+++Y M+ PF D++I ++++ K + R+ D Sbjct: 395 LAPELLLGHGY-TKVVDWWTLGVLLYEMITGLPPFYDENINEMYR----KILQDPLRFPD 449 Query: 555 TISDNCKRLIGLMLEPNHQNRL 576 I + K L+ +L + RL Sbjct: 450 NIDEKAKDLLSGLLTRAPEKRL 471 >SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase Cmk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 335 Score = 122 bits (294), Expect = 2e-28 Identities = 83/289 (28%), Positives = 138/289 (47%), Gaps = 15/289 (5%) Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP 69 ++ LL Y++ + +G G YA V + + + + K + K +DFV Sbjct: 22 DQKQLLPCKYRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKK--QDFV----K 75 Query: 70 REIDVLVRLN--HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127 EI +L R++ HP+++H+ F+ Y+ G+L I G E A Sbjct: 76 NEIAILKRVSYEHPNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALM 135 Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTA---NFNVKLSDFGFSRFCVESDNQPVLSETY 184 R ++YLH+ I HRD+K EN+L + N ++ ++DFG S F D+Q + T Sbjct: 136 RTTTSAVKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSHF--YEDSQYYMLMTA 193 Query: 185 CGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRF 244 CG+ Y APE+ R Y KP D+W++GV+ + +L+ PF ++ E + +Y F Sbjct: 194 CGTPEYMAPEVFRRTGY-GKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTF 252 Query: 245 RSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLN 293 S +S K +K LE DP R +A + L +++ + R T N Sbjct: 253 NDPCWSGISETAKDFIKKCLENDPSKRLTAADALKHPFLS-EKRPATSN 300 Score = 102 bits (244), Expect = 2e-22 Identities = 65/255 (25%), Positives = 122/255 (47%), Gaps = 10/255 (3%) Query: 339 AEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLS--HPHLVHTHSIFQR 396 A R A + + A K+++ + + F+ EI +L ++S HP+++H F+ Sbjct: 43 ATVREAVHIETNKMYAAKIMNKKMMEKK--QDFVKNEIAILKRVSYEHPNILHLVDFFET 100 Query: 397 RYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENV 456 ++ G+L + + +G+ E A R A++Y+H+ I HRD+K EN+ Sbjct: 101 VNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDNGIVHRDLKPENL 160 Query: 457 LLTA---NQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVW 513 L + N ++ ++DFG + D + + T CG+ Y APE+ + T Y KP D+W Sbjct: 161 LYRSKDPNSDLLIADFGLSHFYEDSQYYMLM--TACGTPEYMAPEVFRRTGY-GKPVDMW 217 Query: 514 SLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQ 573 ++G++ Y +L+ PF ++ +A + + F IS+ K I LE + Sbjct: 218 AIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGISETAKDFIKKCLENDPS 277 Query: 574 NRLKIYDIVNSEWIA 588 RL D + +++ Sbjct: 278 KRLTAADALKHPFLS 292 >SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 121 bits (292), Expect = 3e-28 Identities = 76/277 (27%), Positives = 142/277 (51%), Gaps = 20/277 (7%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 ++L K +G G+ + V L +++ D A KII A + EI ++ L Sbjct: 12 WRLGKTLGTGSTSCVRLAKHAKTGD----LAAIKIIPIRYAS-------IGMEILMMRLL 60 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138 HP+++ ++ ++ Y+ + Y +G+L YI K+G +SE +A + Q+ + + H Sbjct: 61 RHPNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCH 120 Query: 139 ELEIAHRDIKCENVLLTAN-FNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197 HRD+K EN+L+ N +K++DFG + VE ++ + E YCGS+ Y APEI+ Sbjct: 121 RFRFRHRDLKLENILIKVNEQQIKIADFGMA--TVEPNDSCL--ENYCGSLHYLAPEIVS 176 Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257 KPY P D+WS GV+L+ +L+ +PF +Y + Y S ++S + Sbjct: 177 HKPYRGAPADVWSCGVILYSLLSNKLPFGGQNTDVIYNKIRHGAYDLPSSISS----AAQ 232 Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNA 294 ++ +L+ +P R + V ++ + L+++++ Sbjct: 233 DLLHRMLDVNPSTRITIPEVFSHPFLMGCTSLSSMDS 269 Score = 118 bits (284), Expect = 3e-27 Identities = 61/214 (28%), Positives = 115/214 (53%), Gaps = 9/214 (4%) Query: 375 EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQL 434 EI M+ L HP+++ + ++ ++ + Y+ G+L ++ + G + E +A + Q+ Sbjct: 53 EILMMRLLRHPNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQI 112 Query: 435 ALAIQYMHELEIAHRDIKCENVLLTAN-QNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493 A+ + H HRD+K EN+L+ N Q +K++DFG A + + N+ E +CGSL Sbjct: 113 LDAVAHCHRFRFRHRDLKLENILIKVNEQQIKIADFGMATV----EPNDSCLENYCGSLH 168 Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553 Y APEI+ PY P DVWS G+++Y +L+ +PF ++ ++ + + S Sbjct: 169 YLAPEIVSHKPYRGAPADVWSCGVILYSLLSNKLPFGGQNTDVIYNKIRHGAYDLPS--- 225 Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587 +IS + L+ ML+ N R+ I ++ + ++ Sbjct: 226 -SISSAAQDLLHRMLDVNPSTRITIPEVFSHPFL 258 >SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 117 bits (282), Expect = 4e-27 Identities = 57/162 (35%), Positives = 95/162 (58%), Gaps = 7/162 (4%) Query: 74 VLVRL-NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLAL 132 VL+RL HP+++ + + + + ++ + Y G+L +L+ G +E + Q+ Sbjct: 60 VLLRLIEHPNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILC 119 Query: 133 GLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQP-VLSETYCGSMSYA 191 GL+Y H+L I HRD+K EN+ L A+ ++K+ +FG + S QP L +T CGS YA Sbjct: 120 GLEYCHKLHICHRDLKPENLYLDAHGSIKIGEFGMA-----SIQQPGKLLQTSCGSPHYA 174 Query: 192 APEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKL 233 +PEI+ G+ Y +D+WS G++ F +L +PFDD +R L Sbjct: 175 SPEIIMGRSYDGCASDIWSCGIIFFALLTGKLPFDDDNIRSL 216 Score = 113 bits (272), Expect = 7e-26 Identities = 60/207 (28%), Positives = 110/207 (53%), Gaps = 8/207 (3%) Query: 375 EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQL 434 E+ +L + HP+++ + + + F+ + YM G+L + +L++G+ E + Q+ Sbjct: 58 ELVLLRLIEHPNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQI 117 Query: 435 ALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSY 494 ++Y H+L I HRD+K EN+ L A+ ++K+ +FG A + KL +T CGS Y Sbjct: 118 LCGLEYCHKLHICHRDLKPENLYLDAHGSIKIGEFGMASIQQPGKL----LQTSCGSPHY 173 Query: 495 TAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYID 554 +PEI+ G Y +D+WS GI+ + +L +PF+D +I+ L ++ S Sbjct: 174 ASPEIIMGRSYDGCASDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQGQFEMPS---- 229 Query: 555 TISDNCKRLIGLMLEPNHQNRLKIYDI 581 IS + L+ ML+ + R+ + I Sbjct: 230 NISPQAQHLLYRMLDVDSSTRITMEQI 256 >SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase Ppk21|Schizosaccharomyces pombe|chr 2|||Manual Length = 550 Score = 116 bits (280), Expect = 8e-27 Identities = 72/264 (27%), Positives = 129/264 (48%), Gaps = 14/264 (5%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y +G+G+++KV ++ + S K A K+++ K+ VK++ E D ++RL Sbjct: 54 YVFGDIIGDGSFSKV---RRATDKKSWKE-YAIKVLDKKYIVKENKVKYVNIERDSMMRL 109 Query: 79 N-HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137 N P + + FQ K Y + NG+LL YI K + EN R + ++ ++Y+ Sbjct: 110 NGFPGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYM 169 Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFC----VESDNQPVLSETYCGSMSYAAP 193 H I HRD+K EN+L N +VK++DFG ++ V S + ++ G+ Y AP Sbjct: 170 HSCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAP 229 Query: 194 EILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILS 253 E+L + K +DLW+ V++ M+ S PF + ++++ M +Y + +L Sbjct: 230 ELL-SRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEY----ELPKLLP 284 Query: 254 LECKTVVKHLLEPDPGLRHSATNV 277 + + HL P R + + Sbjct: 285 PDIVPLFSHLFRIQPSDRSTTQQI 308 Score = 96.3 bits (229), Expect = 1e-20 Identities = 56/196 (28%), Positives = 100/196 (51%), Gaps = 6/196 (3%) Query: 339 AEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLS-HPHLVHTHSIFQRR 397 ++ R A+ A KV+D ++ K++ E + +++L+ P + FQ Sbjct: 66 SKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMRLNGFPGISRLFHTFQDD 125 Query: 398 YKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVL 457 K + + G+LL+++ + + E+ R + ++ +I+YMH I HRD+K EN+L Sbjct: 126 LKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMHSCGIIHRDLKPENIL 185 Query: 458 LTANQNVKLSDFGFARMCVDKKLNEIRSET----FCGSLSYTAPEILQGTPYLPKPTDVW 513 N +VK++DFG A++ K +N T F G+ Y APE+L + K +D+W Sbjct: 186 FDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPELL-SRQVVSKSSDLW 244 Query: 514 SLGIVVYVMLNRAMPF 529 + VVY M+ + PF Sbjct: 245 AFACVVYQMIVGSPPF 260 >SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosaccharomyces pombe|chr 1|||Manual Length = 636 Score = 116 bits (280), Expect = 8e-27 Identities = 81/292 (27%), Positives = 141/292 (48%), Gaps = 17/292 (5%) Query: 5 KTTPSEENTLLTKGY-KLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDF 63 K P++ + + Y + + +G GA+ V + ++S TL + E + P + Sbjct: 336 KKDPAKVSASFVEKYGRCQEVIGRGAFGVVRIAHKVDPQNSGSETLYA-VKEFRRKPAES 394 Query: 64 VVKFLPR---EIDVLVRLNHPHLIHVHSIFQR-KTKYYIFMRYTENGDLLSYILKNGCVS 119 K+ R E + L HP++IH + Q K Y M GDL + I+ G + Sbjct: 395 QKKYTKRLTSEFCISSSLRHPNVIHTLDLIQDGKGDYCEVMELCSGGDLYTLIMAAGRLE 454 Query: 120 ENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSR-FCVESDNQP 178 +A + +QL G+ YLH++ +AHRD+K EN+LLT + ++K++DFG F + + + Sbjct: 455 PMEADCFFKQLMRGVDYLHDMGVAHRDLKPENLLLTVSGSLKITDFGNGECFRMAWEKEA 514 Query: 179 VLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQM 238 ++ CGS Y APE + P+ D+W+ GV+ M + R+ K E + Sbjct: 515 HMTCGLCGSAPYIAPEEYTESEFDPRAVDVWACGVIYMAMRTGRHLW---RVAKKSEDEY 571 Query: 239 GKKY----RFRSRVASILSLE---CKTVVKHLLEPDPGLRHSATNVLDSEWI 283 +Y + S I LE C+ + ++L P+P R +A ++ SEW+ Sbjct: 572 YSRYLMDRKNESGYEPIEMLERSRCRNTLYNILHPNPTYRLTAKQIMKSEWV 623 Score = 101 bits (242), Expect = 3e-22 Identities = 68/235 (28%), Positives = 118/235 (50%), Gaps = 13/235 (5%) Query: 364 PRDFVKKFLPR---EIEMLIKLSHPHLVHTHSIFQR-RYKYFIFMRYMERGDLLEFVLQR 419 P + KK+ R E + L HP+++HT + Q + Y M GDL ++ Sbjct: 391 PAESQKKYTKRLTSEFCISSSLRHPNVIHTLDLIQDGKGDYCEVMELCSGGDLYTLIMAA 450 Query: 420 GAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA---RMCV 476 G ++ +A + +QL + Y+H++ +AHRD+K EN+LLT + ++K++DFG RM Sbjct: 451 GRLEPMEADCFFKQLMRGVDYLHDMGVAHRDLKPENLLLTVSGSLKITDFGNGECFRMAW 510 Query: 477 DKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVM-LNRAMPFEDKHIK 535 +K+ + + CGS Y APE + + P+ DVW+ G++ M R + K + Sbjct: 511 EKEAH--MTCGLCGSAPYIAPEEYTESEFDPRAVDVWACGVIYMAMRTGRHLWRVAKKSE 568 Query: 536 QLHQAQINKNWKFRSRY--IDTIS-DNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587 + ++ + K S Y I+ + C+ + +L PN RL I+ SEW+ Sbjct: 569 DEYYSRYLMDRKNESGYEPIEMLERSRCRNTLYNILHPNPTYRLTAKQIMKSEWV 623 >SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosaccharomyces pombe|chr 1|||Manual Length = 696 Score = 116 bits (278), Expect = 1e-26 Identities = 77/255 (30%), Positives = 130/255 (50%), Gaps = 13/255 (5%) Query: 23 KFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLN--- 79 + +G+G + +VYL K D+++ KI + K V L E ++LVR + Sbjct: 306 RLIGKGTFGQVYLVR---KNDTNRIYAMKKISKKLIVRKKEVTHTLG-ERNILVRTSLDE 361 Query: 80 HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHE 139 P ++ + FQ + Y+ Y G+L ++ G E +A+ + +L L L++LH+ Sbjct: 362 SPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHLHK 421 Query: 140 LEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGK 199 +I +RD+K EN+LL A+ ++ L DFG S+ + ++ + T+CG+ Y APE+L Sbjct: 422 HDIIYRDLKPENILLDADGHIALCDFGLSKANLSAN---ATTNTFCGTTEYLAPEVLLED 478 Query: 200 PYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTV 259 K D WSLGV++F M PF ++++Y K RF +LS E ++ Sbjct: 479 KGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPK---GVLSSEGRSF 535 Query: 260 VKHLLEPDPGLRHSA 274 V+ LL +P R A Sbjct: 536 VRGLLNRNPNHRLGA 550 Score = 99.1 bits (236), Expect = 2e-21 Identities = 59/197 (29%), Positives = 97/197 (49%), Gaps = 6/197 (3%) Query: 346 KNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLS---HPHLVHTHSIFQRRYKYFI 402 KND I A K I R E +L++ S P +V FQ ++ Sbjct: 321 KNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTSLDESPFIVGLKFSFQTASDLYL 380 Query: 403 FMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQ 462 YM G+L + G E +A+ + +L LA++++H+ +I +RD+K EN+LL A+ Sbjct: 381 ITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHLHKHDIIYRDLKPENILLDADG 440 Query: 463 NVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVM 522 ++ L DFG ++ + + TFCG+ Y APE+L K D WSLG++V+ M Sbjct: 441 HIALCDFGLSKANLSANAT---TNTFCGTTEYLAPEVLLEDKGYTKQVDFWSLGVLVFEM 497 Query: 523 LNRAMPFEDKHIKQLHQ 539 PF ++Q+++ Sbjct: 498 CCGWSPFYAPDVQQMYR 514 >SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase Ppk6|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 114 bits (274), Expect = 4e-26 Identities = 71/214 (33%), Positives = 117/214 (54%), Gaps = 13/214 (6%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSH---KSTLACKIIETAKAPKDFVVKFLPREIDVL 75 Y K +G GAY +V L Y S + KS +I+ + +D + +P EI +L Sbjct: 503 YTTIKELGIGAYGQVKLATYKSNKVHEVILKSISKSRILLDSWM-RDKDLGTVPMEISIL 561 Query: 76 VRL---NHPHLIHVHSIFQRKTKYYIFMRYTENG-DLLSYILKNGCVSENQARVWTRQLA 131 L +HP+++ + + F+ YY+ + G DL YI +SE +++ Q+A Sbjct: 562 HFLKAHSHPNIVKMITFFEDNENYYLLTEPQKPGIDLFDYIELKPSISEKESKAIFFQIA 621 Query: 132 LGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYA 191 L + +LH +I HRDIK ENV+L N +L DFG S + N P +T+ G++ +A Sbjct: 622 LAVAHLHSFDIIHRDIKDENVILEGNGCARLIDFGSSSL---TKNGPF--DTFRGTVGFA 676 Query: 192 APEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 APE+LRG+ Y K D+W+LG++L+ ++ + P+ Sbjct: 677 APELLRGEKYLGKEQDIWALGILLYTIVYRENPY 710 Score = 109 bits (262), Expect = 1e-24 Identities = 77/267 (28%), Positives = 143/267 (53%), Gaps = 23/267 (8%) Query: 335 RVYLAEYRNASKNDKL--SILACKVIDTSTAPRDFVKKFLPREIEMLIKL---SHPHLVH 389 +V LA Y++ ++ + SI +++ S RD +P EI +L L SHP++V Sbjct: 516 QVKLATYKSNKVHEVILKSISKSRILLDSWM-RDKDLGTVPMEISILHFLKAHSHPNIVK 574 Query: 390 THSIFQRRYKYFIFMRYMERG-DLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAH 448 + F+ Y++ + G DL +++ + ++ E +++ Q+ALA+ ++H +I H Sbjct: 575 MITFFEDNENYYLLTEPQKPGIDLFDYIELKPSISEKESKAIFFQIALAVAHLHSFDIIH 634 Query: 449 RDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPK 508 RDIK ENV+L N +L DFG + + + +TF G++ + APE+L+G YL K Sbjct: 635 RDIKDENVILEGNGCARLIDFGSSSLTKNGPF-----DTFRGTVGFAAPELLRGEKYLGK 689 Query: 509 PTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLML 568 D+W+LGI++Y ++ R P+ +I+++ A++ ++ +D I C+ ML Sbjct: 690 EQDIWALGILLYTIVYRENPY--YNIEEILDAKLRIPFELSKDNVDLI---CR-----ML 739 Query: 569 EPNHQNRLKIYDIVNSEWIAMDSRLLE 595 + N +R+ I + + W D R L+ Sbjct: 740 DRNVHDRITIEETLQHHWFD-DIRYLD 765 >SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalytic subunit Pka1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 512 Score = 113 bits (273), Expect = 6e-26 Identities = 78/254 (30%), Positives = 129/254 (50%), Gaps = 14/254 (5%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 + + +G G++ +V+L + + ++ A K++E K ++ E +L R+ Sbjct: 201 FNFLQTLGTGSFGRVHLVQ----SNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILSRV 256 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138 HP + + FQ ++ M + E G+L S + K E A+ + ++ L L YLH Sbjct: 257 QHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLH 316 Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198 +I +RD+K EN+LL ++K+ DFGF++ V + N T CG+ Y APEI+ Sbjct: 317 HNQIVYRDLKPENLLLDRFGHLKIVDFGFAK-RVSTSN----CCTLCGTPDYLAPEIISL 371 Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258 KPY K D WSLG+++F ML PF KLYE + K + S S S++ Sbjct: 372 KPY-NKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPS-YFSPASID--- 426 Query: 259 VVKHLLEPDPGLRH 272 ++ HLL+ D R+ Sbjct: 427 LLSHLLQRDITCRY 440 Score = 96.3 bits (229), Expect = 1e-20 Identities = 59/189 (31%), Positives = 98/189 (51%), Gaps = 10/189 (5%) Query: 378 MLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALA 437 +L ++ HP + FQ F+ M + E G+L + + E A+ + ++ LA Sbjct: 252 ILSRVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILA 311 Query: 438 IQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAP 497 + Y+H +I +RD+K EN+LL ++K+ DFGFA K+++ T CG+ Y AP Sbjct: 312 LDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFA-----KRVSTSNCCTLCGTPDYLAP 366 Query: 498 EILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLH----QAQINKNWKFRSRYI 553 EI+ PY K D WSLGI+++ ML PF ++ +L+ + ++N F I Sbjct: 367 EIISLKPY-NKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASI 425 Query: 554 DTISDNCKR 562 D +S +R Sbjct: 426 DLLSHLLQR 434 >SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces pombe|chr 3|||Manual Length = 496 Score = 111 bits (268), Expect = 2e-25 Identities = 76/278 (27%), Positives = 133/278 (47%), Gaps = 8/278 (2%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y + + +G GA+A V L Y + K T+ + + EI + Sbjct: 10 YHIGREIGTGAFASVRLC-YDDNAKIYAVKFVNKKHATSCMNAGVWARRMASEIQLHKLC 68 Query: 79 N-HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137 N H ++IH ++ + ++ + + + GDL I + + E+ A+ + QL G+ ++ Sbjct: 69 NGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFM 128 Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197 H +AHRD+K EN+LL N N+K+SDFGF+ +L+ GS YAAPEI Sbjct: 129 HSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSP-VGSPPYAAPEIT- 186 Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA--SILSLE 255 + Y D+WS G++LF +L + P+D+ + + + KK R ++LS Sbjct: 187 -QQYDGSKVDVWSCGIILFALLLGNTPWDEA-ISNTGDYLLYKKQCERPSYHPWNLLSPG 244 Query: 256 CKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLN 293 +++ +L DP R+S +V+ W+ + T N Sbjct: 245 AYSIITGMLRSDPFKRYSVKHVVQHPWLTSSTPFRTKN 282 Score = 96.3 bits (229), Expect = 1e-20 Identities = 61/206 (29%), Positives = 101/206 (49%), Gaps = 6/206 (2%) Query: 384 HPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHE 443 H +++H ++ + ++ + + + GDL + + + ED A+ + QL I +MH Sbjct: 71 HKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFMHS 130 Query: 444 LEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGT 503 +AHRD+K EN+LL N N+K+SDFGFA + K + + + GS Y APEI Q Sbjct: 131 KGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSP-VGSPPYAAPEITQ-- 187 Query: 504 PYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRY--IDTISDNCK 561 Y DVWS GI+++ +L P+ D+ I + K R Y + +S Sbjct: 188 QYDGSKVDVWSCGIILFALLLGNTPW-DEAISNTGDYLLYKKQCERPSYHPWNLLSPGAY 246 Query: 562 RLIGLMLEPNHQNRLKIYDIVNSEWI 587 +I ML + R + +V W+ Sbjct: 247 SIITGMLRSDPFKRYSVKHVVQHPWL 272 >SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizosaccharomyces pombe|chr 1|||Manual Length = 646 Score = 111 bits (266), Expect = 4e-25 Identities = 75/255 (29%), Positives = 127/255 (49%), Gaps = 13/255 (5%) Query: 23 KFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLN--- 79 K +G+G + +VYL K+D+ + A K++ + V E D+LV+ + Sbjct: 270 KLIGKGTFGQVYLVR---KKDTER-VYAMKVLSKKVIVRRKEVAHTVGERDILVQTSAAD 325 Query: 80 HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHE 139 P ++ + FQ Y+ Y G+L ++ K+ E +A+ + +L L LQ LH+ Sbjct: 326 SPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQALHK 385 Query: 140 LEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGK 199 I +RD+K EN+LL ++ L DFG S+ + + + T+CG+ Y APE++ + Sbjct: 386 RGIVYRDLKPENILLDVQGHIALCDFGLSK---ANLSVGTTTRTFCGTTDYLAPEVILDE 442 Query: 200 PYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTV 259 D WSLGV+L+ M PF ++LY+ + K RF +LS+E + + Sbjct: 443 AGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRF---PRGLLSVEARDL 499 Query: 260 VKHLLEPDPGLRHSA 274 +K LL +P R A Sbjct: 500 IKLLLNRNPKHRLGA 514 Score = 91.5 bits (217), Expect = 3e-19 Identities = 64/234 (27%), Positives = 110/234 (47%), Gaps = 9/234 (3%) Query: 346 KNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLS---HPHLVHTHSIFQRRYKYFI 402 K D + A KV+ R E ++L++ S P +V FQ ++ Sbjct: 285 KKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSAADSPFIVALRFSFQTPKDLYL 344 Query: 403 FMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQ 462 YM G+L + + E++A+ + +L LA+Q +H+ I +RD+K EN+LL Sbjct: 345 VTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQALHKRGIVYRDLKPENILLDVQG 404 Query: 463 NVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVM 522 ++ L DFG ++ + + TFCG+ Y APE++ D WSLG+++Y M Sbjct: 405 HIALCDFGLSKANLSVGTT---TRTFCGTTDYLAPEVILDEAGYDMMVDFWSLGVLLYEM 461 Query: 523 LNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRL 576 PF + +QL++ + +F +S + LI L+L N ++RL Sbjct: 462 TCGWSPFYADNTQQLYKNIVFGKVRFPR---GLLSVEARDLIKLLLNRNPKHRL 512 >SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosaccharomyces pombe|chr 1|||Manual Length = 988 Score = 111 bits (266), Expect = 4e-25 Identities = 72/265 (27%), Positives = 135/265 (50%), Gaps = 16/265 (6%) Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP 69 ++N + + +G+G + KV L EY +K A K+++ K+ ++ L Sbjct: 655 KKNRVTLDDFTFLAVLGKGNFGKVMLAEYKV----NKKFYAIKVLKKEAILKNEELESLK 710 Query: 70 RE---IDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVW 126 E +V + HP L+++ + FQ T+ Y M Y GDL+ +I + S +AR + Sbjct: 711 TEKHVFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQQ-FSVKRARFY 769 Query: 127 TRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCG 186 ++ L L+Y HE IA+RD+K +N+LL + +++++D+G C E+ + T+CG Sbjct: 770 GAEVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYG---LCKENMLLGNTTSTFCG 826 Query: 187 SMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRS 246 + + APEIL + Y K D W+ GV+++ ML PF ++++ + + F Sbjct: 827 TPEFMAPEILLEQQY-SKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPI 885 Query: 247 RVASILSLECKTVVKHLLEPDPGLR 271 + + + ++++ LL DP R Sbjct: 886 NMPA----DAVSLLRGLLTRDPNQR 906 Score = 103 bits (246), Expect = 1e-22 Identities = 70/240 (29%), Positives = 123/240 (51%), Gaps = 11/240 (4%) Query: 335 RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIF 394 +V LAEY+ K + +L + I + K E+ K HP L++ + F Sbjct: 677 KVMLAEYKVNKKFYAIKVLKKEAILKNEELESL--KTEKHVFEVANKEKHPFLLNLFASF 734 Query: 395 QRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCE 454 Q + + M Y+ GDL+ + QR +AR + ++ LA++Y HE IA+RD+K + Sbjct: 735 QTSTRVYFVMEYILGGDLMVHI-QRQQFSVKRARFYGAEVCLALKYFHENGIAYRDLKLD 793 Query: 455 NVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWS 514 N+LL + +++++D+G +C + L + TFCG+ + APEIL Y K D W+ Sbjct: 794 NILLCPDGHIRIADYG---LCKENMLLGNTTSTFCGTPEFMAPEILLEQQY-SKDVDWWA 849 Query: 515 LGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLML-EPNHQ 573 G+++Y ML PF+ + +++ A ++ F I+ +D L GL+ +PN + Sbjct: 850 FGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFP---INMPADAVSLLRGLLTRDPNQR 906 >SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 436 Score = 109 bits (263), Expect = 9e-25 Identities = 68/252 (26%), Positives = 125/252 (49%), Gaps = 16/252 (6%) Query: 25 VGEGAYAKVYLTEYSS--KEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPH 82 +G G+Y KV L + + + + K I+ AK ++ E +L + HP Sbjct: 97 LGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKG-----LEQTKNERQILEEVRHPF 151 Query: 83 LIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEI 142 + ++ FQ + Y+ ++Y G+L S++ + + E+ +T +L L L +LH+L I Sbjct: 152 ICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKLGI 211 Query: 143 AHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYC 202 +RD+K EN LL A ++ L+DFG S+ + ++ G+ Y APEIL +PY Sbjct: 212 VYRDLKPENCLLDAEGHILLTDFGLSKVAENGAD----CRSFVGTEEYCAPEILLEQPY- 266 Query: 203 PKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKH 262 D WS+G+++F +L S PF +++ E K R + + ++ + + ++ Sbjct: 267 DHAVDWWSMGILIFDLLTGSPPFTANNHKRIME----KITRAKPNIPFYVTSDARDIINK 322 Query: 263 LLEPDPGLRHSA 274 L+ +P R A Sbjct: 323 FLKKNPKQRLGA 334 Score = 97.5 bits (232), Expect = 5e-21 Identities = 56/202 (27%), Positives = 106/202 (52%), Gaps = 9/202 (4%) Query: 375 EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQL 434 E ++L ++ HP + + FQ + ++ ++Y G+L + ++ + ED +T +L Sbjct: 140 ERQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAEL 199 Query: 435 ALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSY 494 LA+ ++H+L I +RD+K EN LL A ++ L+DFG +++ N +F G+ Y Sbjct: 200 TLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAE----NGADCRSFVGTEEY 255 Query: 495 TAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYID 554 APEIL PY D WS+GI+++ +L + PF + H+ + K + + Sbjct: 256 CAPEILLEQPY-DHAVDWWSMGILIFDLLTGSPPFTANN----HKRIMEKITRAKPNIPF 310 Query: 555 TISDNCKRLIGLMLEPNHQNRL 576 ++ + + +I L+ N + RL Sbjct: 311 YVTSDARDIINKFLKKNPKQRL 332 >SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizosaccharomyces pombe|chr 1|||Manual Length = 513 Score = 109 bits (261), Expect = 2e-24 Identities = 78/270 (28%), Positives = 128/270 (47%), Gaps = 12/270 (4%) Query: 20 KLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLN 79 KL +GEGA + + + +K + + + ++T+ + V++ E L Sbjct: 242 KLNNVIGEGASSFIRVINDRNKLPIYVAKVFRPPLDTSLLRR--YVRYFIAEYTFASTLR 299 Query: 80 HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHE 139 HP++I V I ++ + Y DL ++I K C S +A QL G+ Y+H Sbjct: 300 HPNIIKVLDIIYKRHTILQIIEYVPY-DLFTFITKGHC-SALKADQMFFQLLDGVAYMHS 357 Query: 140 LEIAHRDIKCENVLLTANFNVKLSDFGFS-RFCVESDNQPVLSETYCGSMSYAAPEILRG 198 L IAHRDIK +N++L N NVK+ DFG + F ++ ++S+ GS Y APE+L Sbjct: 358 LGIAHRDIKLDNIMLDENLNVKIIDFGTAFVFHYPFESTTLMSDGVVGSKPYVAPEVLTQ 417 Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPF-----DDTRMRKLYEQQMGKKYRFRSRVASILS 253 KPY P D+WS +V + K P+ D R LY Q +S++ L Sbjct: 418 KPYDPSAVDVWSCAIVYCCIALKRFPWKVPHTSDKRF-NLYVTQRNDP-NTKSQLIESLP 475 Query: 254 LECKTVVKHLLEPDPGLRHSATNVLDSEWI 283 + + + H+L+ D R S + + W+ Sbjct: 476 MNSRDTIYHMLDIDFNTRCSISGARSTTWM 505 Score = 98.7 bits (235), Expect = 2e-21 Identities = 79/257 (30%), Positives = 123/257 (47%), Gaps = 18/257 (7%) Query: 342 RNASKNDKLSILACKV----IDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRR 397 R + +KL I KV +DTS R +V+ F+ E L HP+++ I +R Sbjct: 256 RVINDRNKLPIYVAKVFRPPLDTSLLRR-YVRYFIA-EYTFASTLRHPNIIKVLDIIYKR 313 Query: 398 YKYFIFMRYMERGDLLEFVLQR--GAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCEN 455 + + Y+ DL F+ + A++ DQ QL + YMH L IAHRDIK +N Sbjct: 314 HTILQIIEYVPY-DLFTFITKGHCSALKADQMFF---QLLDGVAYMHSLGIAHRDIKLDN 369 Query: 456 VLLTANQNVKLSDFGFARMC-VDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWS 514 ++L N NVK+ DFG A + + + S+ GS Y APE+L PY P DVWS Sbjct: 370 IMLDENLNVKIIDFGTAFVFHYPFESTTLMSDGVVGSKPYVAPEVLTQKPYDPSAVDVWS 429 Query: 515 LGIVVYVMLNRAMPFEDKHIK----QLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEP 570 IV + + P++ H L+ Q N + +S+ I+++ N + I ML+ Sbjct: 430 CAIVYCCIALKRFPWKVPHTSDKRFNLYVTQRN-DPNTKSQLIESLPMNSRDTIYHMLDI 488 Query: 571 NHQNRLKIYDIVNSEWI 587 + R I ++ W+ Sbjct: 489 DFNTRCSISGARSTTWM 505 >SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharomyces pombe|chr 2|||Manual Length = 1016 Score = 108 bits (260), Expect = 2e-24 Identities = 64/203 (31%), Positives = 111/203 (54%), Gaps = 10/203 (4%) Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACK--IIETAKAPKDFVVKFLPREIDVLVRLNHPH 82 +G+G + KV L E S++ + + K I+E + K R V R HP Sbjct: 689 LGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVES---TKSEKRVFLVANRERHPF 745 Query: 83 LIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEI 142 L+++HS FQ +T+ Y M + GDL+ +I + S +A+ + ++ L L+Y H+ I Sbjct: 746 LVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQEQ-FSRRRAQFYAAEVCLALKYFHDNGI 804 Query: 143 AHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYC 202 +RD+K +N+LL+ + +VK++D+G + + DN + T+CG+ + APEIL + Y Sbjct: 805 IYRDLKLDNILLSPDGHVKVADYGLCKEDMWHDN---TTATFCGTPEFMAPEILLEQQY- 860 Query: 203 PKPTDLWSLGVVLFVMLNKSMPF 225 + D W+ GV+++ ML PF Sbjct: 861 TRSVDWWAFGVLIYQMLLGQSPF 883 Score = 99 bits (238), Expect = 1e-21 Identities = 49/157 (31%), Positives = 91/157 (57%), Gaps = 5/157 (3%) Query: 384 HPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHE 443 HP LV+ HS FQ + + M ++ GDL+ + Q+ +A+ + ++ LA++Y H+ Sbjct: 743 HPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHI-QQEQFSRRRAQFYAAEVCLALKYFHD 801 Query: 444 LEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGT 503 I +RD+K +N+LL+ + +VK++D+G +C + ++ + TFCG+ + APEIL Sbjct: 802 NGIIYRDLKLDNILLSPDGHVKVADYG---LCKEDMWHDNTTATFCGTPEFMAPEILLEQ 858 Query: 504 PYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQA 540 Y + D W+ G+++Y ML PF + +++ A Sbjct: 859 QY-TRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDA 894 >SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 652 Score = 108 bits (259), Expect = 3e-24 Identities = 83/281 (29%), Positives = 142/281 (50%), Gaps = 24/281 (8%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKII-ETAKAPK------DFVVKFLPRE 71 Y++ K +G G + KV L ++ + LA KII +T + PK + + RE Sbjct: 135 YEIIKELGRGMHGKVKL----GRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVRRE 190 Query: 72 IDVLVRLNHPHLIHVHSIFQ--RKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129 I +L + HP+++ + + TK Y+ + Y G++ + +S ++AR + R Sbjct: 191 IAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRD 250 Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFC---VESDNQPVLSETYCG 186 + LGL+YLH I HRDIK N+LL ++ VK+SDFG S + DN L++T G Sbjct: 251 VVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNEDNDVELAKT-VG 309 Query: 187 SMSYAAPEIL-----RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKK 241 + ++ APE+ R +P + D+W+LGV LF +L PF+ + +L+++ + ++ Sbjct: 310 TPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPFNASMEYELFDKIVNER 369 Query: 242 YRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282 S + E + ++K LL DP R + V W Sbjct: 370 LNIPS--TPDIGEEGRDLLKRLLCKDPEQRITLVEVKLHPW 408 Score = 81.4 bits (192), Expect = 4e-16 Identities = 56/227 (24%), Positives = 108/227 (47%), Gaps = 11/227 (4%) Query: 369 KKFLPREIEMLIKLSHPHLVHTHSIFQ--RRYKYFIFMRYMERGDLLEFVLQRGAVQEDQ 426 K+ + REI +L K HP++V + K ++ + YM G++ + + Sbjct: 184 KEKVRREIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISE 243 Query: 427 ARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVD--KKLNEIR 484 AR + R + L ++Y+H I HRDIK N+LL ++ VK+SDFG + + + N++ Sbjct: 244 ARQYFRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNEDNDVE 303 Query: 485 SETFCGSLSYTAPEIL-----QGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQ 539 G+ ++ APE+ + P + + DVW+LG+ ++ +L PF +L Sbjct: 304 LAKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRCPFNASMEYELFD 363 Query: 540 AQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586 +N+ S I + + L+ +L + + R+ + ++ W Sbjct: 364 KIVNERLNIPS--TPDIGEEGRDLLKRLLCKDPEQRITLVEVKLHPW 408 >SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 658 Score = 106 bits (254), Expect = 1e-23 Identities = 66/211 (31%), Positives = 113/211 (53%), Gaps = 13/211 (6%) Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84 +G+GA VY S+++ ++A K + + PK +F+ EI V+ +H +++ Sbjct: 392 IGQGASGDVY----SARQVGTNLSVAIKKMNINQQPKK---EFIVNEILVMKSHHHKNIV 444 Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144 + F K++ ++ M Y G L ++ N +SE Q ++ GLQ+LHE I H Sbjct: 445 NFIDTFFYKSELWMVMEYMRGGSLTE-VVTNNTLSEGQIAAICKETLEGLQHLHENGIVH 503 Query: 145 RDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPK 204 RDIK +N+LL+ ++KL+DFG FC + D+ T G+ + APE++ K Y K Sbjct: 504 RDIKSDNILLSLQGDIKLTDFG---FCAQIDSNMTKRTTMVGTPYWMAPEVVTRKEYGFK 560 Query: 205 PTDLWSLGVVLFVMLNKSMPF-DDTRMRKLY 234 D+WSLG++ M+ P+ ++ +R LY Sbjct: 561 -VDVWSLGIMAIEMVEGEPPYLNENPLRALY 590 Score = 88.2 bits (209), Expect = 3e-18 Identities = 55/177 (31%), Positives = 92/177 (51%), Gaps = 8/177 (4%) Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412 +A K ++ + P+ K+F+ EI ++ H ++V+ F + + ++ M YM G L Sbjct: 412 VAIKKMNINQQPK---KEFIVNEILVMKSHHHKNIVNFIDTFFYKSELWMVMEYMRGGSL 468 Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472 E V+ + E Q ++ +Q++HE I HRDIK +N+LL+ ++KL+DFGF Sbjct: 469 TE-VVTNNTLSEGQIAAICKETLEGLQHLHENGIVHRDIKSDNILLSLQGDIKLTDFGF- 526 Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF 529 C N + T G+ + APE++ Y K DVWSLGI+ M+ P+ Sbjct: 527 --CAQIDSNMTKRTTMVGTPYWMAPEVVTRKEYGFK-VDVWSLGIMAIEMVEGEPPY 580 >SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc7|Schizosaccharomyces pombe|chr 2|||Manual Length = 1062 Score = 105 bits (251), Expect = 3e-23 Identities = 71/262 (27%), Positives = 123/262 (46%), Gaps = 14/262 (5%) Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84 +G+GA+ VY + T+A K ++ +K K + + EID+L L+HP+++ Sbjct: 15 LGKGAFGAVY----RGLNIKNGETVAVKKVKLSKMLKSDL-SVIKMEIDLLKNLDHPNIV 69 Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144 +Q I + Y ENG L S G + EN ++T Q+ GL YLH + H Sbjct: 70 KYRGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQGVIH 129 Query: 145 RDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPK 204 RDIK N+L T + +KL+DFG V + + + GS + APE++ Sbjct: 130 RDIKGANILTTKDGTIKLADFG-----VATKINALEDHSVVGSPYWMAPEVIE-LVGATT 183 Query: 205 PTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLL 264 +D+WS+G + +L+ + P+ D + + ++ + S +S K+ + Sbjct: 184 ASDIWSVGCTVIELLDGNPPYYDLDPTSALFRMVKDEH---PPLPSNISSAAKSFLMQCF 240 Query: 265 EPDPGLRHSATNVLDSEWIAMD 286 + DP LR +L W+ M+ Sbjct: 241 QKDPNLRIKTRKLLKHPWVIMN 262 Score = 88.6 bits (210), Expect = 2e-18 Identities = 48/157 (30%), Positives = 79/157 (50%), Gaps = 6/157 (3%) Query: 375 EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQL 434 EI++L L HP++V +Q I + Y E G L G + E+ ++T Q+ Sbjct: 56 EIDLLKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQV 115 Query: 435 ALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSY 494 + Y+H + HRDIK N+L T + +KL+DFG A K+N + + GS + Sbjct: 116 LQGLLYLHNQGVIHRDIKGANILTTKDGTIKLADFGVA-----TKINALEDHSVVGSPYW 170 Query: 495 TAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531 APE+++ +D+WS+G V +L+ P+ D Sbjct: 171 MAPEVIE-LVGATTASDIWSVGCTVIELLDGNPPYYD 206 >SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1401 Score = 102 bits (245), Expect = 1e-22 Identities = 72/241 (29%), Positives = 108/241 (44%), Gaps = 11/241 (4%) Query: 71 EIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQL 130 E+ VL RLNHP+++ + + + K YIFM + + G L + EN +V+ QL Sbjct: 1086 EMTVLERLNHPNVVTYYGVEVHREKVYIFMEFCQGGSLADLLAHGRIEDENVLKVYVVQL 1145 Query: 131 ALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVE--------SDNQPVLSE 182 GL Y+H I HRDIK N+LL +K SDFG + + D QP L Sbjct: 1146 LEGLAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQH 1205 Query: 183 TYCGSMSYAAPEILRG-KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKK 241 G+ Y APEI+ G K D+WSLG V+ M+ S P+ + + Sbjct: 1206 L-AGTPMYMAPEIILGTKKGDFGAMDIWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAM 1264 Query: 242 YRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALK 301 + +S + ++ E DP R A ++L WI D R T+ + A + Sbjct: 1265 HTPSIPQNEKISSLARDFIEQCFERDPEQRPRAVDLLTHPWIT-DFRKKTIITMPPATIT 1323 Query: 302 R 302 + Sbjct: 1324 K 1324 Score = 94.3 bits (224), Expect = 5e-20 Identities = 79/294 (26%), Positives = 129/294 (43%), Gaps = 27/294 (9%) Query: 343 NASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFI 402 N D L++ K+ D+ T R V + + E+ +L +L+HP++V + + R K +I Sbjct: 1056 NMETGDLLAVKEIKLQDSRTF-RSTVDQ-IHNEMTVLERLNHPNVVTYYGVEVHREKVYI 1113 Query: 403 FMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQ 462 FM + + G L + + E+ +++ QL + Y+H I HRDIK N+LL Sbjct: 1114 FMEFCQGGSLADLLAHGRIEDENVLKVYVVQLLEGLAYIHSQHILHRDIKPANILLDHRG 1173 Query: 463 NVKLSDFGFARMCVDKKLNEIRSET-------FCGSLSYTAPEILQGTPYLP-KPTDVWS 514 +K SDFG A E+R E G+ Y APEI+ GT D+WS Sbjct: 1174 MIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMYMAPEIILGTKKGDFGAMDIWS 1233 Query: 515 LGIVVYVMLNRAMPFEDK--------HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGL 566 LG V+ M+ + P+ + H+ +H I +N K S D I + C Sbjct: 1234 LGCVILEMMTGSTPWSEMDNEWAIMYHVAAMHTPSIPQNEKISSLARDFI-EQC------ 1286 Query: 567 MLEPNHQNRLKIYDIVNSEWIA-MDSRLLEWTPQETLAYKKAREEKNKLHKTVE 619 E + + R + D++ WI + + P T+ K + KT + Sbjct: 1287 -FERDPEQRPRAVDLLTHPWITDFRKKTIITMPPATITKKTSLSHTITEEKTAQ 1339 >SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosaccharomyces pombe|chr 3|||Manual Length = 592 Score = 102 bits (244), Expect = 2e-22 Identities = 74/272 (27%), Positives = 123/272 (45%), Gaps = 21/272 (7%) Query: 9 SEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68 S N +K + +GEG+Y+ V ++ E+S K A K+++ K+ K++ Sbjct: 89 STPNIKRVSDFKFGEILGEGSYSTVL----TATENSTKREYAIKVLDKRHIIKEKKEKYV 144 Query: 69 PREIDVLVRLN-HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127 E + L L+ HP I + FQ Y + NG+LL YI K G +E A+ + Sbjct: 145 NIEKEALCILSKHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYA 204 Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVES-----------DN 176 + + Y+H + HRD+K EN+LL N K++DFG ++ S D Sbjct: 205 ALIVDSIDYMHGRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADK 264 Query: 177 QPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ 236 S ++ G+ Y +PE+L K +D+W+ G +LF ML PF ++ Sbjct: 265 PQAHSRSFVGTARYVSPEVLSDK-IAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQS 323 Query: 237 QMGKKYRFRSRVASILSLECKTVVKHLLEPDP 268 + Y ++ + S ++K LL DP Sbjct: 324 ILHLSYEIPPDISDVAS----DLIKKLLVLDP 351 Score = 91.5 bits (217), Expect = 3e-19 Identities = 75/285 (26%), Positives = 133/285 (46%), Gaps = 28/285 (9%) Query: 331 ESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLS-HPHLVH 389 E ++ L N++K + A KV+D ++ +K++ E E L LS HP + Sbjct: 107 EGSYSTVLTATENSTKRE----YAIKVLDKRHIIKEKKEKYVNIEKEALCILSKHPGFIK 162 Query: 390 THSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHR 449 FQ + + + G+LL+++ + G E A+ + + +I YMH + HR Sbjct: 163 LFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMHGRGVIHR 222 Query: 450 DIKCENVLLTANQNVKLSDFGFARMC-------------VDKKLNEIRSETFCGSLSYTA 496 D+K EN+LL N K++DFG A++ DK + S +F G+ Y + Sbjct: 223 DLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKP--QAHSRSFVGTARYVS 280 Query: 497 PEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTI 556 PE+L +D+W+ G +++ ML PF + Q+ ++ +++ D Sbjct: 281 PEVL-SDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIPPDISDVA 339 Query: 557 SDNCKRLIGLMLEPNHQNRLKIYDIVNSEW---IAMDSRLLEWTP 598 SD K+L L+L+P ++RL + +I + I D+ L E P Sbjct: 340 SDLIKKL--LVLDP--KDRLTVDEIHQHPFFNGIKFDNTLWELPP 380 >SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 589 Score = 98.3 bits (234), Expect = 3e-21 Identities = 73/263 (27%), Positives = 128/263 (48%), Gaps = 15/263 (5%) Query: 25 VGEGAYAKVYLTEY-SSKEDSHKSTLACKIIET-AKAPKDFVVKFLPREIDVLVRLNHPH 82 +G+GA VYL + K+ ++A K I+ + K+ ++ EI V+ HP+ Sbjct: 315 LGQGASGSVYLAKVVGGKQLGIFDSVAIKSIDLQCQTRKELILN----EITVMRESIHPN 370 Query: 83 LI-HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELE 141 ++ ++ S R+ ++ M Y G L I K+ AR+ + G+Q+LH Sbjct: 371 IVTYLDSFLVRERHLWVVMEYMNAGSLTDIIEKSKLTEAQIARICL-ETCKGIQHLHARN 429 Query: 142 IAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPY 201 I HRDIK +NVLL + N+K++DFG FC N+ T G+ + APE+++ Y Sbjct: 430 IIHRDIKSDNVLLDNSGNIKITDFG---FCARLSNRTNKRVTMVGTPYWMAPEVVKQNEY 486 Query: 202 CPKPTDLWSLGVVLFVMLNKSMPF-DDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVV 260 K D+WSLG+++ M+ P+ + +R LY + K + +++S K+ + Sbjct: 487 GTK-VDIWSLGIMIIEMIENEPPYLREDPIRALY--LIAKNGTPTLKKPNLVSKNLKSFL 543 Query: 261 KHLLEPDPGLRHSATNVLDSEWI 283 L D R +A +L ++ Sbjct: 544 NSCLTIDTIFRATAAELLTHSFL 566 Score = 95.9 bits (228), Expect = 2e-20 Identities = 77/275 (28%), Positives = 127/275 (46%), Gaps = 16/275 (5%) Query: 300 LKRAKEDRRKLS----DVHKHPPKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILAC 355 L R DR+ L+ V H P ++ + ++ VYLA+ + +A Sbjct: 283 LSRRMTDRQALAMLKDSVTSHDPVEYFNVKHKLGQGASGSVYLAKVVGGKQLGIFDSVAI 342 Query: 356 KVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLV-HTHSIFQRRYKYFIFMRYMERGDLLE 414 K ID R K+ + EI ++ + HP++V + S R ++ M YM G L + Sbjct: 343 KSIDLQCQTR---KELILNEITVMRESIHPNIVTYLDSFLVRERHLWVVMEYMNAGSLTD 399 Query: 415 FVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARM 474 + + + ARI + IQ++H I HRDIK +NVLL + N+K++DFGF Sbjct: 400 IIEKSKLTEAQIARICL-ETCKGIQHLHARNIIHRDIKSDNVLLDNSGNIKITDFGF--- 455 Query: 475 CVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF-EDKH 533 C + T G+ + APE+++ Y K D+WSLGI++ M+ P+ + Sbjct: 456 CARLSNRTNKRVTMVGTPYWMAPEVVKQNEYGTK-VDIWSLGIMIIEMIENEPPYLREDP 514 Query: 534 IKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLML 568 I+ L+ I KN + + +S N K + L Sbjct: 515 IRALY--LIAKNGTPTLKKPNLVSKNLKSFLNSCL 547 >SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizosaccharomyces pombe|chr 3|||Manual Length = 338 Score = 94.7 bits (225), Expect = 4e-20 Identities = 69/251 (27%), Positives = 117/251 (46%), Gaps = 13/251 (5%) Query: 8 PSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKF 67 P+ N +K+ +G+G+++ V++ ++ K A K I K + +K Sbjct: 19 PNATNFESVSQFKIRNVIGKGSWSTVFVVKHRQT----KQRFALKCINKKKHD-EHKIKK 73 Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127 L E+ +L LNHP L +S F+ +TK Y+ GDL Y + +E+ R+W Sbjct: 74 LRNEVLLLQSLNHPLLCKFYSEFEDETKIYLVTDLMLGGDL-RYHISQRKFNESVIRIWM 132 Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187 +L L Y+H + HRD+K +N+LL + KL+DF + V + + P S G Sbjct: 133 VELVSALIYIHSKGVLHRDVKPDNILLDEKGHCKLADFNVAA-KVHTSSSPSKSNMTVGR 191 Query: 188 MS---YAAPE-ILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYR 243 + Y APE ++ Y K +D WSLG+ + L + PF + + +K Sbjct: 192 VGTPVYMAPETLIHAVSY--KESDWWSLGITFYECLFQVRPFPNHLLINWIRASEEEKAS 249 Query: 244 FRSRVASILSL 254 R++S L + Sbjct: 250 SADRLSSALHI 260 Score = 82.6 bits (195), Expect = 2e-16 Identities = 60/180 (33%), Positives = 86/180 (47%), Gaps = 9/180 (5%) Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLL 413 A K I+ +KK L E+ +L L+HP L +S F+ K ++ M GDL Sbjct: 57 ALKCINKKKHDEHKIKK-LRNEVLLLQSLNHPLLCKFYSEFEDETKIYLVTDLMLGGDLR 115 Query: 414 EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFAR 473 + QR E RIW +L A+ Y+H + HRD+K +N+LL + KL+DF A Sbjct: 116 YHISQR-KFNESVIRIWMVELVSALIYIHSKGVLHRDVKPDNILLDEKGHCKLADFNVAA 174 Query: 474 MCVDKKLNEIRSETFCGSLS---YTAPE-ILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF 529 V + +S G + Y APE ++ Y K +D WSLGI Y L + PF Sbjct: 175 K-VHTSSSPSKSNMTVGRVGTPVYMAPETLIHAVSY--KESDWWSLGITFYECLFQVRPF 231 >SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|Schizosaccharomyces pombe|chr 3|||Manual Length = 624 Score = 92.3 bits (219), Expect = 2e-19 Identities = 49/151 (32%), Positives = 82/151 (54%), Gaps = 4/151 (2%) Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84 +G+G Y V+L + K ++H+ LA K+++ + + VK + E D+L N L+ Sbjct: 168 LGQGGYGSVWLAK---KRNTHE-LLAMKMMKKSTLQQLNEVKHILNERDILTNTNSEWLV 223 Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144 ++ FQ K K Y+ M Y GD +++ G + ENQ R + ++ + +H+L H Sbjct: 224 KLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAISAVHKLGYMH 283 Query: 145 RDIKCENVLLTANFNVKLSDFGFSRFCVESD 175 RD+K EN L+ ++KLSDFG S V S+ Sbjct: 284 RDLKPENFLIDQKGHIKLSDFGLSTAIVTSN 314 Score = 78.2 bits (184), Expect = 3e-15 Identities = 42/133 (31%), Positives = 70/133 (52%) Query: 344 ASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIF 403 A K + +LA K++ ST + K + E ++L + LV + FQ + K ++ Sbjct: 179 AKKRNTHELLAMKMMKKSTLQQLNEVKHILNERDILTNTNSEWLVKLYYAFQDKEKVYLA 238 Query: 404 MRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQN 463 M Y+ GD F+ +G + E+Q R + ++ AI +H+L HRD+K EN L+ + Sbjct: 239 MEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAISAVHKLGYMHRDLKPENFLIDQKGH 298 Query: 464 VKLSDFGFARMCV 476 +KLSDFG + V Sbjct: 299 IKLSDFGLSTAIV 311 Score = 36.7 bits (81), Expect = 0.010 Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Query: 186 GSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLY 234 GS Y APE++ GK Y + D WSLG + + L PF + +++ + Sbjct: 359 GSPEYMAPEVVYGKKY-DRTVDYWSLGCICYECLVGYPPFSGSTLQETW 406 >SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces pombe|chr 1|||Manual Length = 471 Score = 90.6 bits (215), Expect = 6e-19 Identities = 61/191 (31%), Positives = 93/191 (48%), Gaps = 8/191 (4%) Query: 344 ASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIF 403 A +N I+A K ID T D + +E+ ML + +++ + F Y +I Sbjct: 26 ARENVSGDIIAIKQIDLETGIDDITD--IEQEVFMLSNCNSSNVIQYYGCFVDGYTLWIL 83 Query: 404 MRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQ- 462 M +M+ G + +L+ G + E I R++ + Y+H HRDIK N+LL+++ Sbjct: 84 MEHMDGGSV-SGLLKMGRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAANILLSSSTG 142 Query: 463 NVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVM 522 NVKL+DFG A + R TF G+ + APE++Q T Y D+WSLGI M Sbjct: 143 NVKLADFGVAAQLSNA---ASRRHTFVGTPFWMAPEVIQQTSY-GLAADIWSLGITAIEM 198 Query: 523 LNRAMPFEDKH 533 N P H Sbjct: 199 ANGIPPRATMH 209 Score = 87.0 bits (206), Expect = 7e-18 Identities = 72/272 (26%), Positives = 126/272 (46%), Gaps = 17/272 (6%) Query: 14 LLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREID 73 L Y L + +G G++ V+ ++E+ +A K I+ D + + +E+ Sbjct: 4 LNANSYTLLRKLGSGSFGVVW----KARENVSGDIIAIKQIDLETGIDD--ITDIEQEVF 57 Query: 74 VLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALG 133 +L N ++I + F +I M + + G + S +LK G ++E + R++ G Sbjct: 58 MLSNCNSSNVIQYYGCFVDGYTLWILMEHMDGGSV-SGLLKMGRLNEQVISIILREVLYG 116 Query: 134 LQYLHELEIAHRDIKCENVLLTANF-NVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAA 192 L YLH HRDIK N+LL+++ NVKL+DFG + + N T+ G+ + A Sbjct: 117 LNYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVA---AQLSNAASRRHTFVGTPFWMA 173 Query: 193 PEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTR-MRKLYEQQMGKKYRFRSRVASI 251 PE+++ Y D+WSLG+ M N P MR ++E + ++ Sbjct: 174 PEVIQQTSY-GLAADIWSLGITAIEMANGIPPRATMHPMRVIFEIPQSEP----PKLDDH 228 Query: 252 LSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283 S + V L+ +P +R SA +L +I Sbjct: 229 FSPTFRDFVSCCLDLNPNMRWSAKELLQHPFI 260 >SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2|Schizosaccharomyces pombe|chr 2|||Manual Length = 659 Score = 90.2 bits (214), Expect = 8e-19 Identities = 59/207 (28%), Positives = 96/207 (46%), Gaps = 9/207 (4%) Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR---EIDVLVRLNHP 81 +G G++ +VYL +S + + I+++ KD K L EI +L L+H Sbjct: 400 IGSGSFGQVYLGMNASSGEL--MAVKQVILDSVSESKDRHAKLLDALAGEIALLQELSHE 457 Query: 82 HLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELE 141 H++ IF+ Y G + + G E + + +Q GL+YLH Sbjct: 458 HIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHSRG 517 Query: 142 IAHRDIKCENVLLTANFNVKLSDFGFSR---FCVESDNQPVLSETYCGSMSYAAPEILRG 198 I HRDIK N+L+ +K+SDFG S+ S ++ GS + APE+++ Sbjct: 518 IVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVVKQ 577 Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPF 225 + K TD+WSLG ++ ML P+ Sbjct: 578 TMHTEK-TDIWSLGCLVIEMLTSKHPY 603 Score = 87.8 bits (208), Expect = 4e-18 Identities = 61/204 (29%), Positives = 103/204 (50%), Gaps = 16/204 (7%) Query: 335 RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPR---EIEMLIKLSHPHLVHTH 391 +VYL NAS + +++ ++D+ + +D K L EI +L +LSH H+V Sbjct: 407 QVYLG--MNASSGELMAVKQV-ILDSVSESKDRHAKLLDALAGEIALLQELSHEHIVQYL 463 Query: 392 SIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDI 451 IF+ Y+ G + + G+ +E + + +Q ++Y+H I HRDI Sbjct: 464 GSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHSRGIVHRDI 523 Query: 452 KCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSET------FCGSLSYTAPEILQGTPY 505 K N+L+ +K+SDFG ++ +LN ++T F GS + APE+++ T + Sbjct: 524 KGANILVDNKGKIKISDFGISKKL---ELNSTSTKTGGARPSFQGSSFWMAPEVVKQTMH 580 Query: 506 LPKPTDVWSLGIVVYVMLNRAMPF 529 K TD+WSLG +V ML P+ Sbjct: 581 TEK-TDIWSLGCLVIEMLTSKHPY 603 >SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schizosaccharomyces pombe|chr 1|||Manual Length = 504 Score = 89.8 bits (213), Expect = 1e-18 Identities = 70/250 (28%), Positives = 122/250 (48%), Gaps = 29/250 (11%) Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433 +E+ ++ ++ H ++V+ + Y + M E G+L ++ E+ AR Q Sbjct: 111 KEVNIMRRVKHKNVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLARHIIIQ 170 Query: 434 LALAIQYMHEL-EIAHRDIKCENVLL-----TANQNV--------KLSD---------FG 470 +A A++++H++ I HRDIK EN+L +QN KL + G Sbjct: 171 VAEAVKHLHDVCGIVHRDIKPENLLFQPIEYLPSQNYTPPSLEPNKLDEGMFLEGIGAGG 230 Query: 471 FARMCV-----DKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNR 525 R+ + K + ++ T CG++ Y APEI+ Y K D+W++G V++ ML Sbjct: 231 IGRILIADFGFSKVVWNSKTATPCGTVGYAAPEIVNDELY-SKNVDMWAMGCVLHTMLCG 289 Query: 526 AMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSE 585 PF D++IK L +N ++F S + D ISD+ K LI +L + + R I+ Sbjct: 290 FPPFFDENIKDLASKVVNGEFEFLSPWWDDISDSAKDLITHLLTVDPRERYDIHQFFQHP 349 Query: 586 WIAMDSRLLE 595 WI +S++ E Sbjct: 350 WIKGESKMPE 359 Score = 69.7 bits (163), Expect = 1e-12 Identities = 41/130 (31%), Positives = 66/130 (50%), Gaps = 6/130 (4%) Query: 160 VKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVML 219 + ++DFGFS+ S + T CG++ YAAPEI+ + Y K D+W++G VL ML Sbjct: 234 ILIADFGFSKVVWNSK-----TATPCGTVGYAAPEIVNDELYS-KNVDMWAMGCVLHTML 287 Query: 220 NKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLD 279 PF D ++ L + + ++ F S +S K ++ HLL DP R+ Sbjct: 288 CGFPPFFDENIKDLASKVVNGEFEFLSPWWDDISDSAKDLITHLLTVDPRERYDIHQFFQ 347 Query: 280 SEWIAMDSRL 289 WI +S++ Sbjct: 348 HPWIKGESKM 357 Score = 67.7 bits (158), Expect = 5e-12 Identities = 41/136 (30%), Positives = 74/136 (54%), Gaps = 6/136 (4%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y+L + +G+GA+++VY YS H + + E K + V K E++++ R+ Sbjct: 65 YQLIENLGDGAFSQVYKA-YSIDRKEHVAVKVIRKYEMNKKQRQGVFK----EVNIMRRV 119 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138 H +++++ + + Y++ M E G+L I+ SEN AR Q+A +++LH Sbjct: 120 KHKNVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLARHIIIQVAEAVKHLH 179 Query: 139 EL-EIAHRDIKCENVL 153 ++ I HRDIK EN+L Sbjct: 180 DVCGIVHRDIKPENLL 195 >SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces pombe|chr 1|||Manual Length = 312 Score = 89.8 bits (213), Expect = 1e-18 Identities = 67/215 (31%), Positives = 107/215 (49%), Gaps = 13/215 (6%) Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411 I+A KV+D A +D ++ L +EI LI L+ H+ ++ F ++ +I M Y + G Sbjct: 31 IVALKVVDLD-ATKDQIET-LTQEINFLIDLNSVHITKYYASFVDGFRLWITMEYCDGGS 88 Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471 L+ + G E RQ+ A+ Y+H HRDIK N+L + VKL+DFG Sbjct: 89 CLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMKDGLVKLADFGV 148 Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531 + + L + +++ F G+ + APE+++ T Y K D+WSLGI Y + P+ Sbjct: 149 SGQL--ESLRD-KNDDFVGTPFWMAPEVVKQTGYNYK-ADIWSLGITAYELATGEPPYSG 204 Query: 532 KH-IKQL-----HQAQINKNWKFRSRYIDTISDNC 560 H +K L H + KF + D +S NC Sbjct: 205 IHPMKVLLLIPKHSPPSLERSKFSRAFCDFVS-NC 238 Score = 87.0 bits (206), Expect = 7e-18 Identities = 58/215 (26%), Positives = 106/215 (49%), Gaps = 10/215 (4%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y+ + +G+G++ V+ +++ +A K+++ A KD ++ L +EI+ L+ L Sbjct: 6 YRDLQLIGQGSFGSVF----RAQDVESSKIVALKVVDL-DATKD-QIETLTQEINFLIDL 59 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138 N H+ ++ F + +I M Y + G L + +G SE RQ+ L YLH Sbjct: 60 NSVHITKYYASFVDGFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLH 119 Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198 HRDIK N+L + VKL+DFG S + ++ ++ + G+ + APE+++ Sbjct: 120 GQGKMHRDIKAANILTMKDGLVKLADFGVSG---QLESLRDKNDDFVGTPFWMAPEVVKQ 176 Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKL 233 Y K D+WSLG+ + + P+ K+ Sbjct: 177 TGYNYK-ADIWSLGITAYELATGEPPYSGIHPMKV 210 >SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizosaccharomyces pombe|chr 1|||Manual Length = 566 Score = 89.0 bits (211), Expect = 2e-18 Identities = 68/270 (25%), Positives = 118/270 (43%), Gaps = 32/270 (11%) Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84 +G+G +VYL +E A K++ + K K E +L NHP ++ Sbjct: 201 LGKGDVGRVYLV----REKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILATSNHPFIV 256 Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNG--CVSENQARVWTRQLALGLQYLHELEI 142 ++ FQ Y+ M Y G+ + + C+SEN+A+ + ++ L+YLH + Sbjct: 257 TLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLMGF 316 Query: 143 AHRDIKCENVLLTANFNVKLSDFGFSR--------FCVESDNQPVLSETYC--------- 185 +RD+K EN+LL + ++ LSDF S+ +++ N P Y Sbjct: 317 IYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYALDTKSCIAD 376 Query: 186 -------GSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQM 238 G+ Y APE+++G + D W+LG++ + ML + PF + + Sbjct: 377 FRTNSFVGTEEYIAPEVIKGCGH-TSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNIL 435 Query: 239 GKKYRFRSRV-ASILSLECKTVVKHLLEPD 267 K F A +S CK +++ LL D Sbjct: 436 HKDVIFPEYADAPSISSLCKNLIRKLLVKD 465 Score = 85.8 bits (203), Expect = 2e-17 Identities = 77/320 (24%), Positives = 144/320 (45%), Gaps = 39/320 (12%) Query: 286 DSRLTTLNAVEAAALKRAKEDRRKLSDVHKHPPKRQGDILEGPTRESAFRVYLAEYRNAS 345 + L + A + + K+ DV P + L G + RVYL + + Sbjct: 161 EKELAHIKKTVATRARTYSSNSIKICDVEVGPSSFEKVFLLG--KGDVGRVYLVREKKSG 218 Query: 346 KNDKLSILACK-VIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFM 404 K + +L+ + +I + + R F ++ + L +HP +V + FQ ++ M Sbjct: 219 KFYAMKVLSKQEMIKRNKSKRAFAEQHI------LATSNHPFIVTLYHSFQSDEYLYLCM 272 Query: 405 RYMERGDLLEFVLQRGA--VQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQ 462 Y G+ + +R + E++A+ + ++ A++Y+H + +RD+K EN+LL + Sbjct: 273 EYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLMGFIYRDLKPENILLHESG 332 Query: 463 NVKLSDFGFARM----------------------CVDKK--LNEIRSETFCGSLSYTAPE 498 ++ LSDF ++ +D K + + R+ +F G+ Y APE Sbjct: 333 HIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYALDTKSCIADFRTNSFVGTEEYIAPE 392 Query: 499 ILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYID--TI 556 +++G + D W+LGI+ Y ML PF+ K+ ++K+ F Y D +I Sbjct: 393 VIKGCGH-TSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNILHKDVIF-PEYADAPSI 450 Query: 557 SDNCKRLIGLMLEPNHQNRL 576 S CK LI +L + +RL Sbjct: 451 SSLCKNLIRKLLVKDENDRL 470 >SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizosaccharomyces pombe|chr 2|||Manual Length = 461 Score = 89.0 bits (211), Expect = 2e-18 Identities = 63/225 (28%), Positives = 103/225 (45%), Gaps = 15/225 (6%) Query: 23 KFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPK----DFVVKFLPREIDVLVRL 78 K + +GA + + + + K K A K+ K + +V FL RE + +L Sbjct: 124 KSIAKGATSTIKVVTHRDKITDAKIYYAAKVYRKTKTSHKKRLNTMVYFL-REWSIQPKL 182 Query: 79 NHPHLIHV-------HSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLA 131 +HP+++ V S+F + + + Y GDL I + E++ + +Q+ Sbjct: 183 DHPNILKVICPCVTLTSVFNKSAGFCLVQEYCPQGDLFKQIEEKVLTLEDKC-CYLKQIL 241 Query: 132 LGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVE-SDNQPV-LSETYCGSMS 189 + YL IAHRD+K EN+L+ + +KL+DFG S DN+ + GS++ Sbjct: 242 QAVAYLQSQRIAHRDLKPENILIGRDGLLKLTDFGTSEIVGNPGDNESIRFVSGAVGSLA 301 Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLY 234 Y APE YC D WS G++L V+ PF + LY Sbjct: 302 YLAPEAFHENEYCGLLADRWSCGILLKVLFTGYFPFKTSVKTDLY 346 Score = 79.0 bits (186), Expect = 2e-15 Identities = 52/166 (31%), Positives = 85/166 (51%), Gaps = 10/166 (6%) Query: 374 REIEMLIKLSHPHL-------VHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQ 426 RE + KL HP++ V S+F + + + Y +GDL + + ++ ED+ Sbjct: 174 REWSIQPKLDHPNILKVICPCVTLTSVFNKSAGFCLVQEYCPQGDLFKQIEEKVLTLEDK 233 Query: 427 ARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNE-IRS 485 + +Q+ A+ Y+ IAHRD+K EN+L+ + +KL+DFG + + + NE IR Sbjct: 234 C-CYLKQILQAVAYLQSQRIAHRDLKPENILIGRDGLLKLTDFGTSEIVGNPGDNESIRF 292 Query: 486 ET-FCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530 + GSL+Y APE Y D WS GI++ V+ PF+ Sbjct: 293 VSGAVGSLAYLAPEAFHENEYCGLLADRWSCGILLKVLFTGYFPFK 338 >SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|Schizosaccharomyces pombe|chr 3|||Manual Length = 288 Score = 88.6 bits (210), Expect = 2e-18 Identities = 48/152 (31%), Positives = 85/152 (55%), Gaps = 7/152 (4%) Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVL---QRGAVQEDQARIW 430 REI ++ +L HP+++ + Q K + YME+ DL +++ +GA+ Q + + Sbjct: 48 REISLMKELRHPNIMSLSDVLQTENKLMLVFEYMEK-DLKKYMDTYGNQGALPPSQVKNF 106 Query: 431 TRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCG 490 T+QL I + HE + HRD+K +N+L+ + +KL+DFG AR + +N +E Sbjct: 107 TQQLLKGISFCHENRVLHRDLKPQNLLINSRGELKLADFGLAR-SIGIPVNTFSNEVV-- 163 Query: 491 SLSYTAPEILQGTPYLPKPTDVWSLGIVVYVM 522 +L Y AP++L G+ D+WS+G ++ M Sbjct: 164 TLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEM 195 Score = 83.4 bits (197), Expect = 9e-17 Identities = 57/204 (27%), Positives = 99/204 (48%), Gaps = 15/204 (7%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y+ + +GEG YA VY + +A K+I + REI ++ L Sbjct: 3 YQRLEKLGEGTYAHVY----KGQNRVTGEIVALKVIRIDA--DEGTPSTAIREISLMKEL 56 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYIL---KNGCVSENQARVWTRQLALGLQ 135 HP+++ + + Q + K + Y E DL Y+ G + +Q + +T+QL G+ Sbjct: 57 RHPNIMSLSDVLQTENKLMLVFEYMEK-DLKKYMDTYGNQGALPPSQVKNFTQQLLKGIS 115 Query: 136 YLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLS-ETYCGSMSYAAPE 194 + HE + HRD+K +N+L+ + +KL+DFG +R S PV + ++ Y AP+ Sbjct: 116 FCHENRVLHRDLKPQNLLINSRGELKLADFGLAR----SIGIPVNTFSNEVVTLWYRAPD 171 Query: 195 ILRGKPYCPKPTDLWSLGVVLFVM 218 +L G D+WS+G ++ M Sbjct: 172 VLLGSRVYSTSIDIWSVGCIMAEM 195 >SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 1116 Score = 87.8 bits (208), Expect = 4e-18 Identities = 73/273 (26%), Positives = 125/273 (45%), Gaps = 13/273 (4%) Query: 23 KFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDF----VVKFLPREIDVLVRL 78 + +G G Y KV+L + + +I +T D +V + EI ++ L Sbjct: 829 ELIGNGTYGKVFLA-MNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISMIADL 887 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138 +H +++ + +T IF+ Y G + + G E R +RQ+ GL YLH Sbjct: 888 DHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRFVSRQVLYGLSYLH 947 Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVE-SDNQPVLSETYCGSMSYAAPEILR 197 I HRD+K +N+L+ + K+SDFG S+ DN LS GS+ + APE++ Sbjct: 948 SKGIIHRDLKADNLLIDFDGVCKISDFGISKHSDNVYDNDANLSMQ--GSIFWMAPEVIH 1005 Query: 198 G--KPYCPKPTDLWSLGVVLFVMLNKSMPFD-DTRMRKLYEQQMGKKY-RFRSRVASILS 253 + Y K D+WSLG V+ ML P+ D ++ +++ KK S + S +S Sbjct: 1006 NDHQGYSAK-VDVWSLGCVVLEMLAGRRPWSTDEAIQAMFKLGTEKKAPPIPSELVSQVS 1064 Query: 254 LECKTVVKHLLEPDPGLRHSATNVLDSEWIAMD 286 E + + +R +A +L+ ++ D Sbjct: 1065 PEAIQFLNACFTVNADVRPTAEELLNHPFMKCD 1097 Score = 80.6 bits (190), Expect = 6e-16 Identities = 64/264 (24%), Positives = 118/264 (44%), Gaps = 12/264 (4%) Query: 335 RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKK----FLPREIEMLIKLSHPHLVHT 390 +V+LA N + + +++ ++ T D ++K + EI M+ L H ++V Sbjct: 838 KVFLA--MNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISMIADLDHLNIVQY 895 Query: 391 HSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRD 450 + IF+ Y+ G + + G +E R +RQ+ + Y+H I HRD Sbjct: 896 LGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRFVSRQVLYGLSYLHSKGIIHRD 955 Query: 451 IKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQG--TPYLPK 508 +K +N+L+ + K+SDFG ++ D + + + GS+ + APE++ Y K Sbjct: 956 LKADNLLIDFDGVCKISDFGISKHS-DNVYDNDANLSMQGSIFWMAPEVIHNDHQGYSAK 1014 Query: 509 PTDVWSLGIVVYVMLNRAMPFE-DKHIKQLHQAQINKNW-KFRSRYIDTISDNCKRLIGL 566 DVWSLG VV ML P+ D+ I+ + + K S + +S + + Sbjct: 1015 -VDVWSLGCVVLEMLAGRRPWSTDEAIQAMFKLGTEKKAPPIPSELVSQVSPEAIQFLNA 1073 Query: 567 MLEPNHQNRLKIYDIVNSEWIAMD 590 N R +++N ++ D Sbjct: 1074 CFTVNADVRPTAEELLNHPFMKCD 1097 >SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Schizosaccharomyces pombe|chr 3|||Manual Length = 830 Score = 87.4 bits (207), Expect = 5e-18 Identities = 82/292 (28%), Positives = 130/292 (44%), Gaps = 49/292 (16%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y + +G G++A VY K ++ K + T K K +++ L EI +L + Sbjct: 14 YVIRSEIGRGSFAIVY----KGKHTETNRVISIKSVLTKKLTKK-LLENLESEISILKEI 68 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKN---------------------GC 117 H H++ + + ++ M Y GDL +I K Sbjct: 69 RHVHVVELIDCIKAGRFIHLVMEYCSLGDLSYFIRKREKFNSIPSLAWINIDHPPVYKAG 128 Query: 118 VSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLL----TANF--------------N 159 ++E R +T+QLA LQ+L + HRD+K +N+LL TA + Sbjct: 129 LNETLVRHFTQQLASALQFLRSRSLIHRDVKPQNLLLQPPPTAAYLEEHPQFVGSPKLPM 188 Query: 160 VKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVML 219 +KL+DFGF+R+ S ++ET CGS Y APEILR + Y K DLWS+G VL+ M Sbjct: 189 LKLADFGFARYLQTSS----MAETLCGSPLYMAPEILRYEKYDAK-ADLWSVGAVLYEMA 243 Query: 220 NKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLR 271 PF +L + K + + + + KT++ LL+ +P R Sbjct: 244 VGKPPFKAPNHVELLRRIQKAKDVIKFPEEAFIHPDIKTLICALLKQNPADR 295 Score = 72.1 bits (169), Expect = 2e-13 Identities = 76/270 (28%), Positives = 119/270 (44%), Gaps = 50/270 (18%) Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411 +++ K + T + ++ L EI +L ++ H H+V + + M Y GD Sbjct: 39 VISIKSVLTKKLTKKLLEN-LESEISILKEIRHVHVVELIDCIKAGRFIHLVMEYCSLGD 97 Query: 412 LLEFVLQR---------------------GAVQEDQARIWTRQLALAIQYMHELEIAHRD 450 L F+ +R + E R +T+QLA A+Q++ + HRD Sbjct: 98 LSYFIRKREKFNSIPSLAWINIDHPPVYKAGLNETLVRHFTQQLASALQFLRSRSLIHRD 157 Query: 451 IKCENVLLTANQN------------------VKLSDFGFARMCVDKKLNEIRSETFCGSL 492 +K +N+LL +KL+DFGFAR + +ET CGS Sbjct: 158 VKPQNLLLQPPPTAAYLEEHPQFVGSPKLPMLKLADFGFARYLQTSSM----AETLCGSP 213 Query: 493 SYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE-DKHIKQLHQAQINKN-WKFRS 550 Y APEIL+ Y K D+WS+G V+Y M PF+ H++ L + Q K+ KF Sbjct: 214 LYMAPEILRYEKYDAK-ADLWSVGAVLYEMAVGKPPFKAPNHVELLRRIQKAKDVIKFPE 272 Query: 551 RYIDTISDNCKRLIGLMLEPNHQNRLKIYD 580 I + K LI +L+ N +R+ YD Sbjct: 273 EAF--IHPDIKTLICALLKQNPADRID-YD 299 >SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosaccharomyces pombe|chr 2|||Manual Length = 652 Score = 86.6 bits (205), Expect = 1e-17 Identities = 74/284 (26%), Positives = 128/284 (45%), Gaps = 18/284 (6%) Query: 11 ENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR 70 EN + Y + VG G+Y VY + K T+A KI+ + V + + Sbjct: 2 ENNTASSPYTKLELVGRGSYGAVYRGICNLT----KETVAIKILNLDTDEDE--VSDIQK 55 Query: 71 EIDVLVRLNHP---HLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127 E+ VL L ++I H + T +I M Y G + + +++ G +SE + Sbjct: 56 EVAVLSELKQSDVENIIKYHGSYLVGTNLWIIMDYCHGGSVRT-LMEAGPISEPCISLIL 114 Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187 R+ L+++H I HRDIK N+L++ + NVKL DFG + E + T+ G+ Sbjct: 115 RETLQALKFIHHAGIIHRDIKAANILVSMSGNVKLCDFGVA---AELNINRRKRITFIGT 171 Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF-DDTRMRKLYEQQMGKKYRFRS 246 + APE++R D+WSLG+ + + S P + R +Y R Sbjct: 172 PYWMAPEVIRDGQEYNVMADIWSLGITAYEIATGSPPHAKEDPFRAVYLIAHTAPPRLNG 231 Query: 247 RVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLT 290 +++L K + L+ P R ++ +L S++I SR++ Sbjct: 232 NFSALL----KEFIASCLQDVPQRRLDSSELLKSKFIKQYSRMS 271 Score = 79.4 bits (187), Expect = 1e-15 Identities = 69/261 (26%), Positives = 119/261 (45%), Gaps = 15/261 (5%) Query: 337 YLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHP---HLVHTHSI 393 Y A YR K ++ A K+++ T D V + +E+ +L +L +++ H Sbjct: 21 YGAVYRGICNLTKETV-AIKILNLDT-DEDEVSD-IQKEVAVLSELKQSDVENIIKYHGS 77 Query: 394 FQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKC 453 + +I M Y G + +++ G + E + R+ A++++H I HRDIK Sbjct: 78 YLVGTNLWIIMDYCHGGSV-RTLMEAGPISEPCISLILRETLQALKFIHHAGIIHRDIKA 136 Query: 454 ENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVW 513 N+L++ + NVKL DFG A + +N + TF G+ + APE+++ D+W Sbjct: 137 ANILVSMSGNVKLCDFGVA---AELNINRRKRITFIGTPYWMAPEVIRDGQEYNVMADIW 193 Query: 514 SLGIVVYVMLNRAMPFEDKHIKQ-LHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNH 572 SLGI Y + + P H K+ +A R S K I L+ Sbjct: 194 SLGITAYEIATGSPP----HAKEDPFRAVYLIAHTAPPRLNGNFSALLKEFIASCLQDVP 249 Query: 573 QNRLKIYDIVNSEWIAMDSRL 593 Q RL +++ S++I SR+ Sbjct: 250 QRRLDSSELLKSKFIKQYSRM 270 >SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 372 Score = 85.4 bits (202), Expect = 2e-17 Identities = 63/214 (29%), Positives = 101/214 (47%), Gaps = 13/214 (6%) Query: 12 NTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPRE 71 N L + Y++ +G+GAY V + K K +A K I P F ++ L RE Sbjct: 32 NFELPEEYEMINLIGQGAYGVVCAALH--KPSGLK--VAVKKIHPFNHPV-FCLRTL-RE 85 Query: 72 IDVLVRLNHPHLIHVHSI-----FQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVW 126 I +L H ++I + I +Q YI E L ++++ +S++ + + Sbjct: 86 IKLLRHFRHENIISILDILPPPSYQELEDVYIVQELMETD--LYRVIRSQPLSDDHCQYF 143 Query: 127 TRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCG 186 T Q+ L+ +H + HRD+K N+LL AN ++K++DFG +R P Y Sbjct: 144 TYQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVA 203 Query: 187 SMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLN 220 + Y APEI+ K DLWS G +L ML+ Sbjct: 204 TRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLS 237 Score = 74.1 bits (174), Expect = 5e-14 Identities = 49/164 (29%), Positives = 80/164 (48%), Gaps = 7/164 (4%) Query: 374 REIEMLIKLSHPHLVHTHSI-----FQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQAR 428 REI++L H +++ I +Q +I ME DL V++ + +D + Sbjct: 84 REIKLLRHFRHENIISILDILPPPSYQELEDVYIVQELMET-DLYR-VIRSQPLSDDHCQ 141 Query: 429 IWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETF 488 +T Q+ A++ MH + HRD+K N+LL AN ++K++DFG AR + N + Sbjct: 142 YFTYQILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEY 201 Query: 489 CGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532 + Y APEI+ K D+WS G ++ ML+ F K Sbjct: 202 VATRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGK 245 >SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 85.4 bits (202), Expect = 2e-17 Identities = 57/208 (27%), Positives = 98/208 (47%), Gaps = 10/208 (4%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y+ +GEG Y KVY + D +A K I + F + + RE+ +L RL Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGD----LVALKRIRLEQEKDGFPITTV-REVKILQRL 331 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGC-VSENQARVWTRQLALGLQYL 137 H +++ + I K+ Y+ Y ++ DL +L + + + ++Q+ L YL Sbjct: 332 RHKNIVRLLEIMVEKSSVYMVFEYMDH-DLTGVLLNSQLHFTPGNIKHLSKQIFEALAYL 390 Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197 H + HRDIK N+LL N ++K +DFG +RF S + + ++ + PE+L Sbjct: 391 HHRGVLHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVI--TLWFRPPELLL 448 Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 G+ D+WS G ++ + PF Sbjct: 449 GETAYDTAVDIWSAGCIVMELFT-GKPF 475 Score = 71.3 bits (167), Expect = 4e-13 Identities = 46/166 (27%), Positives = 77/166 (46%), Gaps = 5/166 (3%) Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGA-VQEDQARIWTR 432 RE+++L +L H ++V I + ++ YM+ DL +L + ++ Sbjct: 323 REVKILQRLRHKNIVRLLEIMVEKSSVYMVFEYMDH-DLTGVLLNSQLHFTPGNIKHLSK 381 Query: 433 QLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSL 492 Q+ A+ Y+H + HRDIK N+LL N ++K +DFG AR K + +L Sbjct: 382 QIFEALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVI--TL 439 Query: 493 SYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK-HIKQL 537 + PE+L G D+WS G +V + F+ + I QL Sbjct: 440 WFRPPELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQGRDEISQL 485 >SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizosaccharomyces pombe|chr 2|||Manual Length = 413 Score = 84.6 bits (200), Expect = 4e-17 Identities = 61/179 (34%), Positives = 88/179 (49%), Gaps = 21/179 (11%) Query: 65 VKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGC--VSENQ 122 VK +EI L L+HP ++ + + + + + Y GDL Y K+ E Sbjct: 149 VKVFRQEIWALKTLSHPCVVQLLNYYVSSAELILVENYCMGGDLYHYTKKHHSDFSLEFV 208 Query: 123 ARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNV---------------KLSDFGF 167 R+++ +L + YLH + HRD+K EN+LLT +NV ++SDF Sbjct: 209 GRIFS-ELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTIDNWKNYPNALIQISDFEL 267 Query: 168 SRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFD 226 S F V+S N V S CGS YA PE+ G + D WSLG+VLF +L +PFD Sbjct: 268 SIF-VDSKNHLVQSS--CGSQEYAPPEVYMGIAHDGFRADAWSLGIVLFALLEGRLPFD 323 Score = 71.7 bits (168), Expect = 3e-13 Identities = 54/178 (30%), Positives = 85/178 (47%), Gaps = 21/178 (11%) Query: 370 KFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGA--VQEDQA 427 K +EI L LSHP +V + + + + Y GDL + + + E Sbjct: 150 KVFRQEIWALKTLSHPCVVQLLNYYVSSAELILVENYCMGGDLYHYTKKHHSDFSLEFVG 209 Query: 428 RIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNV---------------KLSDFGFA 472 RI++ +L + Y+H + HRD+K EN+LLT NV ++SDF + Sbjct: 210 RIFS-ELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTIDNWKNYPNALIQISDFELS 268 Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530 + VD K + ++S CGS Y PE+ G + D WSLGIV++ +L +PF+ Sbjct: 269 -IFVDSKNHLVQSS--CGSQEYAPPEVYMGIAHDGFRADAWSLGIVLFALLEGRLPFD 323 >SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 340 Score = 84.2 bits (199), Expect = 5e-17 Identities = 49/161 (30%), Positives = 85/161 (52%), Gaps = 7/161 (4%) Query: 66 KFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARV 125 K + RE+ VL P+++ + FQ K + M Y + G L + + + G + + Sbjct: 105 KQILRELGVLHHCRSPYIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDILGK 164 Query: 126 WTRQLALGLQYLHE-LEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETY 184 + GL YL+ L I HRD+K NV++ + +KL DFG S V S +++T+ Sbjct: 165 IINSMVKGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGELVNS-----VAQTF 219 Query: 185 CGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 G+ +Y +PE +RG Y K +D+WSLG+ + + + +P+ Sbjct: 220 VGTSTYMSPERIRGGKYTVK-SDIWSLGISIIELATQELPW 259 Score = 78.2 bits (184), Expect = 3e-15 Identities = 48/168 (28%), Positives = 87/168 (51%), Gaps = 7/168 (4%) Query: 368 VKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQA 427 ++K + RE+ +L P++V + FQ + + M YM+ G L + + G + D Sbjct: 103 LQKQILRELGVLHHCRSPYIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDIL 162 Query: 428 RIWTRQLALAIQYMHE-LEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSE 486 + + Y++ L I HRD+K NV++ + +KL DFG V +L ++ Sbjct: 163 GKIINSMVKGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDFG-----VSGELVNSVAQ 217 Query: 487 TFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHI 534 TF G+ +Y +PE ++G Y K +D+WSLGI + + + +P+ +I Sbjct: 218 TFVGTSTYMSPERIRGGKYTVK-SDIWSLGISIIELATQELPWSFSNI 264 >SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 422 Score = 83.8 bits (198), Expect = 7e-17 Identities = 59/207 (28%), Positives = 102/207 (49%), Gaps = 10/207 (4%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 +K+ K +G+GAY V + +D + +A K I T K + K REI +L+ Sbjct: 21 FKVVKELGQGAYGIVCAARNVASKD--QEAVAIKKI-TNVFSKSILTKRALREIKLLIHF 77 Query: 79 -NHPHLIHVHSIF----QRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALG 133 NH ++ ++ + + YI+ E DL + I +++ + + Q+ G Sbjct: 78 RNHRNITCIYDLDIINPYNFNEVYIYEELME-ADLNAIIKSGQPLTDAHFQSFIYQILCG 136 Query: 134 LQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVES-DNQPVLSETYCGSMSYAA 192 L+Y+H + HRD+K N+L+ A+ +K+ DFG +R C E+ + P Y + Y A Sbjct: 137 LKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGFMTEYVATRWYRA 196 Query: 193 PEILRGKPYCPKPTDLWSLGVVLFVML 219 PEI+ K D+WS+G +L +L Sbjct: 197 PEIMLSFSSYHKGIDVWSVGCILAELL 223 Score = 68.5 bits (160), Expect = 3e-12 Identities = 52/207 (25%), Positives = 98/207 (47%), Gaps = 11/207 (5%) Query: 342 RNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKL-SHPHLVHTHSI-FQRRYK 399 RN + D+ ++ K+ T+ + + K REI++LI +H ++ + + Y Sbjct: 39 RNVASKDQEAVAIKKI--TNVFSKSILTKRALREIKLLIHFRNHRNITCIYDLDIINPYN 96 Query: 400 Y---FIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENV 456 + +I+ ME DL + + + + + Q+ ++Y+H + HRD+K N+ Sbjct: 97 FNEVYIYEELME-ADLNAIIKSGQPLTDAHFQSFIYQILCGLKYIHSANVIHRDLKPGNL 155 Query: 457 LLTANQNVKLSDFGFARMCVDK-KLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSL 515 L+ A+ +K+ DFG AR C + + N + + Y APEI+ K DVWS+ Sbjct: 156 LVNADCELKICDFGLARGCSENPEENPGFMTEYVATRWYRAPEIMLSFSSYHKGIDVWSV 215 Query: 516 GIVVYVMLNRAMPFEDKHIKQLHQAQI 542 G ++ +L F+ K +HQ + Sbjct: 216 GCILAELLGGTPLFKGKDF--VHQLNL 240 >SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schizosaccharomyces pombe|chr 2|||Manual Length = 526 Score = 83.4 bits (197), Expect = 9e-17 Identities = 66/280 (23%), Positives = 122/280 (43%), Gaps = 32/280 (11%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 ++ + +G+G KVYL ++ S+ A KI+ + K V + E ++L + Sbjct: 155 FEKIRLLGQGDVGKVYLV----RQKSNHRLFAMKILNKREMIKRHKVNRVLAEQEILTKS 210 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYI--LKNGCVSENQARVWTRQLALGLQY 136 HP ++ ++ FQ + Y+ M Y G+ + L + E A + ++ L+Y Sbjct: 211 KHPFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAALEY 270 Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFS--------------RFCVESDNQPVL-- 180 LH + +RD+K EN+LL + ++ LSDF S + S +P L Sbjct: 271 LHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQEKPALDT 330 Query: 181 --------SETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRK 232 + ++ G+ Y APE++R + D W+LG+ ++ +L + PF Sbjct: 331 NSYFSNFRTNSFVGTEEYIAPEVIRSCGH-TVAVDWWTLGIFIYEILYGTTPFKGKNRHA 389 Query: 233 LYEQQMGKKYRF-RSRVASILSLECKTVVKHLLEPDPGLR 271 + + F A +S CK++++ LL D R Sbjct: 390 TFSNILYSDVSFPEYHGAPNVSSTCKSLIRRLLVKDESKR 429 Score = 72.5 bits (170), Expect = 2e-13 Identities = 55/228 (24%), Positives = 100/228 (43%), Gaps = 28/228 (12%) Query: 375 EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFV--LQRGAVQEDQARIWTR 432 E E+L K HP +V + FQ R ++ M Y G+ + L + + E A + Sbjct: 203 EQEILTKSKHPFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAA 262 Query: 433 QLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFAR------------------- 473 ++ A++Y+H + +RD+K EN+LL + ++ LSDF ++ Sbjct: 263 EVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFS 322 Query: 474 -----MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMP 528 + + + R+ +F G+ Y APE+++ + D W+LGI +Y +L P Sbjct: 323 QEKPALDTNSYFSNFRTNSFVGTEEYIAPEVIRSCGH-TVAVDWWTLGIFIYEILYGTTP 381 Query: 529 FEDKHIKQLHQAQINKNWKFRSRY-IDTISDNCKRLIGLMLEPNHQNR 575 F+ K+ + + F + +S CK LI +L + R Sbjct: 382 FKGKNRHATFSNILYSDVSFPEYHGAPNVSSTCKSLIRRLLVKDESKR 429 >SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosaccharomyces pombe|chr 1|||Manual Length = 722 Score = 81.4 bits (192), Expect = 4e-16 Identities = 64/233 (27%), Positives = 111/233 (47%), Gaps = 34/233 (14%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 YK+ + +G G++ ++Y + +D + LA K I + +++ E+++L L Sbjct: 4 YKILECIGHGSFGRIYKVQ--RLKDG--ALLAQKEIHFGNITRQ-EKQYIADEVNILRNL 58 Query: 79 NHPHLIHV--HSIFQRKTKYYIFMRYTENGDLLSYILK----NGCVSENQARVWTRQLAL 132 HP+++ + + ++M Y +GDL + I + +E + + QL L Sbjct: 59 KHPNIVQYCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLL 118 Query: 133 GLQYLHELE-------------------IAHRDIKCENVLLTANFNVKLSDFGFSRFCVE 173 L H E + HRDIK N+ L N +VKL DFG S+ Sbjct: 119 ALYRCHYGENAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLL-- 176 Query: 174 SDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFD 226 DN V +++Y G+ Y +PEI+R PY K +D+W+LG V+F + + PF+ Sbjct: 177 -DNTRVFTQSYVGTPYYMSPEIIRSSPYSAK-SDVWALGCVIFEICMLTHPFE 227 Score = 74.1 bits (174), Expect = 5e-14 Identities = 71/259 (27%), Positives = 116/259 (44%), Gaps = 33/259 (12%) Query: 351 SILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFI--FMRYME 408 ++LA K I R K+++ E+ +L L HP++V R I +M Y Sbjct: 28 ALLAQKEIHFGNITRQ-EKQYIADEVNILRNLKHPNIVQYCGEELNRSAQVINLYMEYCG 86 Query: 409 RGDLLEFVL----QRGAVQEDQARIWTRQLALAIQYMHELE------------------- 445 GDL + ++ E + + QL LA+ H E Sbjct: 87 HGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALYRCHYGENAPACDSQWPREIFHPKQS 146 Query: 446 IAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPY 505 + HRDIK N+ L N +VKL DFG +++ +D + ++++ G+ Y +PEI++ +PY Sbjct: 147 VLHRDIKPANIFLDENNSVKLGDFGLSKL-LDN--TRVFTQSYVGTPYYMSPEIIRSSPY 203 Query: 506 LPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIG 565 K +DVW+LG V++ + PFE + +L + N S + SD+ LI Sbjct: 204 SAK-SDVWALGCVIFEICMLTHPFEGRSYLELQRNICQGN---LSCWDHHYSDDVFLLIR 259 Query: 566 LMLEPNHQNRLKIYDIVNS 584 LE N R Y ++ S Sbjct: 260 HCLEVNSDLRPTTYQLLRS 278 >SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomyces pombe|chr 2|||Manual Length = 581 Score = 81.0 bits (191), Expect = 5e-16 Identities = 54/160 (33%), Positives = 84/160 (52%), Gaps = 11/160 (6%) Query: 374 REIEMLIKLSH-PHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQE-DQARIWT 431 +E+ +L +L P +V+ +++ F+ + Y E GDL F+ + G +Q D R+W Sbjct: 337 QEVSILQRLQACPFVVNLVNVWSYNDNIFLQLDYCENGDLSLFLSELGLLQVMDPFRVWK 396 Query: 432 R--QLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFC 489 QL A+ ++H LE H D+K NVL+T + N+KL DFG A + ++ Sbjct: 397 MLFQLTQALNFIHLLEFVHLDVKPSNVLITRDGNLKLGDFGLATSLPVSSMVDLE----- 451 Query: 490 GSLSYTAPEILQGTPYLPKPTDVWSLGI-VVYVMLNRAMP 528 G Y APEIL Y KP DV+SLG+ ++ N +P Sbjct: 452 GDRVYIAPEILASHNY-GKPADVYSLGLSMIEAATNVVLP 490 Score = 77.0 bits (181), Expect = 8e-15 Identities = 54/170 (31%), Positives = 89/170 (52%), Gaps = 13/170 (7%) Query: 70 REIDVLVRLNH-PHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSE-NQARVWT 127 +E+ +L RL P ++++ +++ ++ + Y ENGDL ++ + G + + RVW Sbjct: 337 QEVSILQRLQACPFVVNLVNVWSYNDNIFLQLDYCENGDLSLFLSELGLLQVMDPFRVWK 396 Query: 128 R--QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYC 185 QL L ++H LE H D+K NVL+T + N+KL DFG + + PV S Sbjct: 397 MLFQLTQALNFIHLLEFVHLDVKPSNVLITRDGNLKLGDFGL------ATSLPVSSMVDL 450 Query: 186 -GSMSYAAPEILRGKPYCPKPTDLWSLGV-VLFVMLNKSMPFDDTRMRKL 233 G Y APEIL Y KP D++SLG+ ++ N +P + ++L Sbjct: 451 EGDRVYIAPEILASHNY-GKPADVYSLGLSMIEAATNVVLPENGVEWQRL 499 >SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomyces pombe|chr 1|||Manual Length = 607 Score = 80.6 bits (190), Expect = 6e-16 Identities = 44/144 (30%), Positives = 77/144 (53%), Gaps = 4/144 (2%) Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84 VG+G Y V+L K D+ K +A KI+ + K ++ + E D+L N L+ Sbjct: 214 VGQGGYGSVWLAR---KRDT-KEIVALKIMNKSVLHKMDEIRHVLTERDILTTANSEWLV 269 Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144 + FQ + Y+ M + GD + + +G + ++ A+ + ++ L + LH+L H Sbjct: 270 RLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRDHHAKFYATEMFLAIDALHQLGYIH 329 Query: 145 RDIKCENVLLTANFNVKLSDFGFS 168 RD+K EN L+ A+ ++KL+DFG S Sbjct: 330 RDLKPENFLVGASGHIKLTDFGLS 353 Score = 69.7 bits (163), Expect = 1e-12 Identities = 38/136 (27%), Positives = 70/136 (51%) Query: 344 ASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIF 403 A K D I+A K+++ S + + + E ++L + LV FQ ++ Sbjct: 225 ARKRDTKEIVALKIMNKSVLHKMDEIRHVLTERDILTTANSEWLVRLLYAFQDTSNIYLA 284 Query: 404 MRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQN 463 M ++ GD + G +++ A+ + ++ LAI +H+L HRD+K EN L+ A+ + Sbjct: 285 MEFVPGGDFRTLLSNSGVLRDHHAKFYATEMFLAIDALHQLGYIHRDLKPENFLVGASGH 344 Query: 464 VKLSDFGFARMCVDKK 479 +KL+DFG + + KK Sbjct: 345 IKLTDFGLSSGIISKK 360 Score = 43.6 bits (98), Expect = 9e-05 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Query: 178 PVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLY 234 PV + + GS Y APE+LRG+ Y D WSLG +++ L+ PF + + + + Sbjct: 397 PVYAHSVVGSPDYMAPEVLRGENY-NHSVDYWSLGCIMYECLSGFPPFSGSNVNETW 452 Score = 40.7 bits (91), Expect = 6e-04 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 3/65 (4%) Query: 483 IRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQI 542 + + + GS Y APE+L+G Y D WSLG ++Y L+ PF ++ + Sbjct: 398 VYAHSVVGSPDYMAPEVLRGENY-NHSVDYWSLGCIMYECLSGFPPFSGSNVNETWSNL- 455 Query: 543 NKNWK 547 KNW+ Sbjct: 456 -KNWR 459 >SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 80.6 bits (190), Expect = 6e-16 Identities = 62/215 (28%), Positives = 105/215 (48%), Gaps = 9/215 (4%) Query: 14 LLTKGYKLTKFVGEGAYAKVYLTEYSS--KEDSHKSTLACKIIETAKAPKDFVVKFLPRE 71 L K K + +G GA V + + SS K + K A + ET + ++ K + E Sbjct: 297 LFKKYGKFGRMLGSGAGGSVRIMKRSSDGKIFAVKEFRARRPTETER---EYARK-VTAE 352 Query: 72 IDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLA 131 + L+H ++I I + K+Y M Y D+ S ++ +G ++ + +QL Sbjct: 353 FCIGSALHHTNIIETLDIVEENKKFYEVMEYAPY-DMFSIVM-SGKMTMPEVYCCFKQLL 410 Query: 132 LGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFS-RFCVESDNQPVLSETYCGSMSY 190 G+ YLH + +AHRD+K +N+++ +N VK+ DFG + F + V + GS Y Sbjct: 411 SGVAYLHSMGLAHRDLKLDNLVVDSNCFVKIIDFGSAVVFKYPFEADIVEATGVVGSDPY 470 Query: 191 AAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 APE L K Y P+ D+WS ++ M + P+ Sbjct: 471 LAPETLVRKLYDPRAVDIWSSAIIFCCMALRRFPW 505 Score = 73.3 bits (172), Expect = 1e-13 Identities = 43/150 (28%), Positives = 75/150 (50%), Gaps = 3/150 (2%) Query: 382 LSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYM 441 L H +++ T I + K++ M Y D+ V+ G + + +QL + Y+ Sbjct: 359 LHHTNIIETLDIVEENKKFYEVMEYAPY-DMFSIVMS-GKMTMPEVYCCFKQLLSGVAYL 416 Query: 442 HELEIAHRDIKCENVLLTANQNVKLSDFGFARMC-VDKKLNEIRSETFCGSLSYTAPEIL 500 H + +AHRD+K +N+++ +N VK+ DFG A + + + + + GS Y APE L Sbjct: 417 HSMGLAHRDLKLDNLVVDSNCFVKIIDFGSAVVFKYPFEADIVEATGVVGSDPYLAPETL 476 Query: 501 QGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530 Y P+ D+WS I+ M R P++ Sbjct: 477 VRKLYDPRAVDIWSSAIIFCCMALRRFPWK 506 Score = 29.9 bits (64), Expect = 1.2 Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 247 RVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283 R+ +L E + V+ H+LE DP R+ V WI Sbjct: 578 RLLRLLPRETRAVIAHMLELDPVKRYDIHRVFADNWI 614 >SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 474 Score = 80.6 bits (190), Expect = 6e-16 Identities = 71/228 (31%), Positives = 109/228 (47%), Gaps = 29/228 (12%) Query: 14 LLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETA-KAPKDFVVKFLPREI 72 L KGYK+ + + +G+Y V L + T CK ++ A K K FL +E+ Sbjct: 4 LQKKGYKVERPLNKGSYGTVVLAHRLFR------TPRCKDLKYAIKCIKKPAYTFL-QEV 56 Query: 73 DVLVRLN---HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCV-SENQARVWTR 128 ++L +L+ H ++IH F+ YY+ + Y GDL IL N ++NQ + Sbjct: 57 NILRQLSRSRHRNIIHFVESFEDNVYYYVVLEYCPLGDLYECILNNDFPNAKNQPEMIKN 116 Query: 129 ---QLALGLQYLHELEIAHRDIKCENVLLT-----ANFNVKLSDFGFSRFCVESDNQPVL 180 Q+ G+ +LH I HRD+K EN LL+ + VK+SDFG + C + Sbjct: 117 IFLQIIDGVAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLA--C----RDKIS 170 Query: 181 SETYCGSMSYAAPEILR---GKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 + GS Y APE G Y P+ D+W+LG+ L ++ PF Sbjct: 171 YDFGTGSDRYMAPEQFEEVDGAGYSPRAADIWALGICLLNLIFARNPF 218 Score = 73.7 bits (173), Expect = 7e-14 Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 21/177 (11%) Query: 374 REIEMLIKLS---HPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQR----GAVQEDQ 426 +E+ +L +LS H +++H F+ Y++ + Y GDL E +L Q + Sbjct: 54 QEVNILRQLSRSRHRNIIHFVESFEDNVYYYVVLEYCPLGDLYECILNNDFPNAKNQPEM 113 Query: 427 ARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQN-----VKLSDFGFARMCVDKKLN 481 + Q+ + ++H I HRD+K EN LL+ +++ VK+SDFG A C DK Sbjct: 114 IKNIFLQIIDGVAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLA--CRDK--- 168 Query: 482 EIRSETFCGSLSYTAPEILQ---GTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIK 535 I + GS Y APE + G Y P+ D+W+LGI + ++ PF H K Sbjct: 169 -ISYDFGTGSDRYMAPEQFEEVDGAGYSPRAADIWALGICLLNLIFARNPFTYPHEK 224 >SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schizosaccharomyces pombe|chr 2|||Manual Length = 470 Score = 80.2 bits (189), Expect = 8e-16 Identities = 54/188 (28%), Positives = 90/188 (47%), Gaps = 15/188 (7%) Query: 14 LLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREID 73 +L + +G GAY VY ED + TL + K RE+ Sbjct: 13 VLGDSLRFVSIIGAGAYGVVY-----KAEDIYDGTLYAVKALCKDGLNEKQKKLQARELA 67 Query: 74 VLVRLN-HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT--RQL 130 + R++ HP++I +H + + + Y+ ++Y NGDL +YI + N + T QL Sbjct: 68 LHARVSSHPYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQL 127 Query: 131 ALGLQYLHELEIAHRDIKCENVLLTANFN-VKLSDFGFSRFCVESDNQPVLSETYCGSMS 189 +++ H + I HRD+K EN+++ + N V L+DFG + +P S+ CGS+ Sbjct: 128 ISAVEHCHSVGIYHRDLKPENIMVGNDVNTVYLADFGL------ATTEPYSSDFGCGSLF 181 Query: 190 YAAPEILR 197 Y +PE R Sbjct: 182 YMSPECQR 189 Score = 69.3 bits (162), Expect = 2e-12 Identities = 43/148 (29%), Positives = 76/148 (51%), Gaps = 10/148 (6%) Query: 369 KKFLPREIEMLIKLS-HPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQA 427 KK RE+ + ++S HP+++ H + + ++ ++Y GDL ++ ++ Q + Sbjct: 59 KKLQARELALHARVSSHPYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSH 118 Query: 428 RIWT--RQLALAIQYMHELEIAHRDIKCENVLLTANQN-VKLSDFGFARMCVDKKLNEIR 484 I T QL A+++ H + I HRD+K EN+++ + N V L+DFG A Sbjct: 119 LIKTVFLQLISAVEHCHSVGIYHRDLKPENIMVGNDVNTVYLADFGLA------TTEPYS 172 Query: 485 SETFCGSLSYTAPEILQGTPYLPKPTDV 512 S+ CGSL Y +PE + L +D+ Sbjct: 173 SDFGCGSLFYMSPECQREVKKLSSLSDM 200 >SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Ppk34|Schizosaccharomyces pombe|chr 3|||Manual Length = 354 Score = 78.6 bits (185), Expect = 3e-15 Identities = 61/248 (24%), Positives = 113/248 (45%), Gaps = 17/248 (6%) Query: 37 EYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQR--KT 94 E S D ST+ +I K + ++ +E+DVL L+H +++ ++ + K Sbjct: 90 ELGSFNDMDSSTIEDQIRNQEKKDPYYYIR---KELDVLKVLDHENVVKLYQVINSDYKD 146 Query: 95 KYYIFMRYTENGDLLS--YILKNGCVSENQARVWTRQLALGLQYLHELEIAHRDIKCENV 152 + + Y G L S + + + R RQL L + Y+H + HRDIK +N+ Sbjct: 147 SLCMVLNYCPGGKLASVDHGISFDPMPLETCRKSFRQLVLAVNYIHGKGVIHRDIKPDNI 206 Query: 153 LLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG--KPYCPKPTDLWS 210 L N N+ + DFG + F + + G+ ++ APE+ K KP D+WS Sbjct: 207 LFKENNNLCVIDFGLAEFLPKDG----FVKPASGTPAFMAPELFDNELKKIKGKPLDIWS 262 Query: 211 LGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGL 270 +GV L+V+ PF+ + + + GK + + + + + +++ LE +P Sbjct: 263 MGVTLYVIAFAEFPFNGSTILDMINVIKGKSL----MIPAYCNSDLRKLLERCLEKNPEK 318 Query: 271 RHSATNVL 278 R + +L Sbjct: 319 RITIEELL 326 Score = 77.0 bits (181), Expect = 8e-15 Identities = 56/223 (25%), Positives = 105/223 (47%), Gaps = 14/223 (6%) Query: 371 FLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFM--RYMERGDL--LEFVLQRGAVQEDQ 426 ++ +E+++L L H ++V + + YK + M Y G L ++ + + + Sbjct: 117 YIRKELDVLKVLDHENVVKLYQVINSDYKDSLCMVLNYCPGGKLASVDHGISFDPMPLET 176 Query: 427 ARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSE 486 R RQL LA+ Y+H + HRDIK +N+L N N+ + DFG A + S Sbjct: 177 CRKSFRQLVLAVNYIHGKGVIHRDIKPDNILFKENNNLCVIDFGLAEFLPKDGFVKPAS- 235 Query: 487 TFCGSLSYTAPEILQG--TPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINK 544 G+ ++ APE+ KP D+WS+G+ +YV+ PF I + K Sbjct: 236 ---GTPAFMAPELFDNELKKIKGKPLDIWSMGVTLYVIAFAEFPFNGSTILDMINVIKGK 292 Query: 545 NWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587 + + Y ++ + ++L+ LE N + R+ I +++ ++ Sbjct: 293 SLMIPA-YCNS---DLRKLLERCLEKNPEKRITIEELLRDPFL 331 >SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schizosaccharomyces pombe|chr 2|||Manual Length = 398 Score = 78.2 bits (184), Expect = 3e-15 Identities = 78/305 (25%), Positives = 136/305 (44%), Gaps = 17/305 (5%) Query: 7 TPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVK 66 TP ++ Y++ + + EG+Y VY + S + +A K I+ F + Sbjct: 62 TPELKSCNSIDDYEILEKIEEGSYGIVY----RGLDKSTNTLVALKKIKFDPNGIGFPIT 117 Query: 67 FLPREIDVLVRLNHPHLIHVHSIFQRKT--KYYIFMRYTENGDLLSYILKNGCVSENQAR 124 L REI+ L + H +++ + + K Y+ M + E+ L +L N Q+ Sbjct: 118 SL-REIESLSSIRHDNIVELEKVVVGKDLKDVYLVMEFMEHD--LKTLLDNMPEDFLQSE 174 Query: 125 VWTRQLAL--GLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSE 182 V T L L ++H HRD+K N+L+ +KL+DFG +R S+ + L+ Sbjct: 175 VKTLMLQLLAATAFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLAR--PVSEPKSSLTR 232 Query: 183 TYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFD-DTRMRKLYEQQMGKK 241 ++ Y APE+L G P K D+WS+G + M+ ++ F + + +LY+ Sbjct: 233 LVV-TLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLG 291 Query: 242 YRFRSRVASILSLECKTVVKHLLEPDPG-LRHSATNVLDSEWIAMDSRLTTLNAVEAAAL 300 Y R L +KH P +R S N+ + + + +RL +LN + + Sbjct: 292 YPTREEWPQYFLLPYANKIKHPTVPTHSKIRTSIPNLTGNAYDLL-NRLLSLNPAKRISA 350 Query: 301 KRAKE 305 K A E Sbjct: 351 KEALE 355 Score = 74.5 bits (175), Expect = 4e-14 Identities = 66/242 (27%), Positives = 107/242 (44%), Gaps = 12/242 (4%) Query: 374 REIEMLIKLSHPHLVHTHSIFQRR--YKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431 REIE L + H ++V + + ++ M +ME L+ +L Q+ + T Sbjct: 120 REIESLSSIRHDNIVELEKVVVGKDLKDVYLVMEFMEHD--LKTLLDNMPEDFLQSEVKT 177 Query: 432 RQLAL--AIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFC 489 L L A +MH HRD+K N+L+ +KL+DFG AR + K + R Sbjct: 178 LMLQLLAATAFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTR---LV 234 Query: 490 GSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK-HIKQLHQAQINKNWKF 548 +L Y APE+L G P K D+WS+G + M+ R F K + QL++ + Sbjct: 235 VTLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPT 294 Query: 549 RSRYIDTISDNCKRLIGLMLEPNHQN-RLKIYDIVNSEWIAMDSRLLEWTPQETLAYKKA 607 R + I P H R I ++ + + + +RLL P + ++ K+A Sbjct: 295 REEWPQYFLLPYANKIKHPTVPTHSKIRTSIPNLTGNAYDLL-NRLLSLNPAKRISAKEA 353 Query: 608 RE 609 E Sbjct: 354 LE 355 >SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosaccharomyces pombe|chr 1|||Manual Length = 650 Score = 78.2 bits (184), Expect = 3e-15 Identities = 60/206 (29%), Positives = 110/206 (53%), Gaps = 17/206 (8%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y + + VG+G + VYL ++K S K +A K ++ A + RE+ L+RL Sbjct: 36 YNVVRKVGDGTFGSVYLA--TTKTPS-KEVVAIKSMKKKLAKVSDATRL--REVHSLLRL 90 Query: 79 N-HPHLIHVHSIFQRKTK-YYIFMRYTE-NGDLLSYILKNGCVSENQARVWTRQLALGLQ 135 + + +++++ ++ + + +I M + + N L KN ++ Q + RQ+ GL Sbjct: 91 SENENIVNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLN 150 Query: 136 YLHELEIAHRDIKCENVLLTAN-----FNVKLSDFGFSRFCVESDNQPVLSETYCGSMSY 190 ++H HRD+K EN+L+++N FNVK++DFG +R E +++P +E Y + Y Sbjct: 151 HIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAR---EINSRPPYTE-YVSTRWY 206 Query: 191 AAPEILRGKPYCPKPTDLWSLGVVLF 216 APE+L Y P D+++ G + F Sbjct: 207 RAPELLLRDSYYSFPVDIYAAGCMAF 232 Score = 55.2 bits (127), Expect = 3e-08 Identities = 50/195 (25%), Positives = 97/195 (49%), Gaps = 22/195 (11%) Query: 336 VYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLS-HPHLVHTHSIF 394 VYLA + SK ++A K + A + RE+ L++LS + ++V+ ++ Sbjct: 50 VYLATTKTPSKE----VVAIKSMKKKLAKVSDATRL--REVHSLLRLSENENIVNIFDLY 103 Query: 395 QRRYKYF-IFMRYMERGDLLEFVLQR--GAVQEDQARIWTRQLALAIQYMHELEIAHRDI 451 +++ I M +++ +L + + R + +Q + RQ+ + ++H HRD+ Sbjct: 104 IDQFRCLHIVMEFLDC-NLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHTNGFFHRDM 162 Query: 452 KCENVLLTANQ-----NVKLSDFGFARMCVDKKLNEIRSET-FCGSLSYTAPEILQGTPY 505 K EN+L+++N NVK++DFG AR ++N T + + Y APE+L Y Sbjct: 163 KPENILISSNSDSSSFNVKIADFGLAR-----EINSRPPYTEYVSTRWYRAPELLLRDSY 217 Query: 506 LPKPTDVWSLGIVVY 520 P D+++ G + + Sbjct: 218 YSFPVDIYAAGCMAF 232 >SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosaccharomyces pombe|chr 1|||Manual Length = 469 Score = 77.8 bits (183), Expect = 4e-15 Identities = 43/155 (27%), Positives = 81/155 (52%), Gaps = 4/155 (2%) Query: 14 LLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREID 73 L + + K +G+GA+ +V L + K D+ K +++T +D + + E D Sbjct: 88 LSLEDFSTIKVIGKGAFGEVRLVQ---KLDTGKIYAMKSLLKTEMFKRDQLAH-VKAERD 143 Query: 74 VLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALG 133 +LV + P ++ ++ FQ Y+ M + GDL++ ++ SE+ R + + L Sbjct: 144 LLVESDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLA 203 Query: 134 LQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFS 168 + +H + HRDIK +N+L+ + ++KLSDFG S Sbjct: 204 IADVHRMGYIHRDIKPDNILIDRDGHIKLSDFGLS 238 Score = 69.3 bits (162), Expect = 2e-12 Identities = 40/134 (29%), Positives = 68/134 (50%), Gaps = 2/134 (1%) Query: 340 EYRNASKNDKLSILACK-VIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRY 398 E R K D I A K ++ T RD + + E ++L++ P +V + FQ Sbjct: 106 EVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAH-VKAERDLLVESDSPWVVSLYYAFQDSL 164 Query: 399 KYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLL 458 ++ M ++ GDL+ ++ ED R + + LAI +H + HRDIK +N+L+ Sbjct: 165 YLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIADVHRMGYIHRDIKPDNILI 224 Query: 459 TANQNVKLSDFGFA 472 + ++KLSDFG + Sbjct: 225 DRDGHIKLSDFGLS 238 Score = 34.7 bits (76), Expect = 0.041 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%) Query: 176 NQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYE 235 N+ V++ + G+ Y APEI + Y + D WSLG ++F L PF + Y Sbjct: 284 NRRVMAYSTVGTPDYIAPEIFLQQGY-GQDCDWWSLGAIMFECLIGWPPFCSENSHETYR 342 Query: 236 QQMGKKYRFRSRVASILSLECKTVVKHLL 264 + + + LS+E + ++ L+ Sbjct: 343 KIINWRETLTFPNDIHLSIEARDLMDRLM 371 Score = 31.5 bits (68), Expect = 0.38 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 1/71 (1%) Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532 +M KK + + + G+ Y APEI Y + D WSLG +++ L PF + Sbjct: 277 KMATWKKNRRVMAYSTVGTPDYIAPEIFLQQGY-GQDCDWWSLGAIMFECLIGWPPFCSE 335 Query: 533 HIKQLHQAQIN 543 + + ++ IN Sbjct: 336 NSHETYRKIIN 346 >SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 580 Score = 76.6 bits (180), Expect = 1e-14 Identities = 49/138 (35%), Positives = 71/138 (51%), Gaps = 7/138 (5%) Query: 160 VKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVML 219 ++L+DFG S+ +S Q T CG+M Y APEI+R + Y K D+W+LG VL+ +L Sbjct: 304 IRLADFGLSKVVWDSHTQ-----TPCGTMGYTAPEIVRDERYS-KGVDMWALGCVLYTIL 357 Query: 220 NKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLD 279 PF D + L ++ +Y F S +S K ++ HLL DP R+ L Sbjct: 358 CGFPPFYDESISLLTKKVSRGEYSFLSPWWDDISKSAKDLISHLLTVDPESRYDIHQFLA 417 Query: 280 SEWIAMDSRLTTLNAVEA 297 WI+ SR T A +A Sbjct: 418 HPWIS-GSREPTFPATDA 434 Score = 72.9 bits (171), Expect = 1e-13 Identities = 41/125 (32%), Positives = 69/125 (55%), Gaps = 6/125 (4%) Query: 464 VKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVML 523 ++L+DFG +++ D ++T CG++ YTAPEI++ Y K D+W+LG V+Y +L Sbjct: 304 IRLADFGLSKVVWDS-----HTQTPCGTMGYTAPEIVRDERY-SKGVDMWALGCVLYTIL 357 Query: 524 NRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVN 583 PF D+ I L + + F S + D IS + K LI +L + ++R I+ + Sbjct: 358 CGFPPFYDESISLLTKKVSRGEYSFLSPWWDDISKSAKDLISHLLTVDPESRYDIHQFLA 417 Query: 584 SEWIA 588 WI+ Sbjct: 418 HPWIS 422 Score = 62.1 bits (144), Expect = 2e-10 Identities = 40/145 (27%), Positives = 76/145 (52%), Gaps = 14/145 (9%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKA---PKD------FVVKFLP 69 Y L + +G+GA++ VY ++ + +A K+++ A+ P+D + Sbjct: 124 YTLLQKMGDGAFSNVYKAIHNRTGEK----VAIKVVQRAQPNTDPRDPRKRQGVESHNIL 179 Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129 +E+ ++ R+ HP++I + Q YY+ + + G+L I++ SE+ +R Q Sbjct: 180 KEVQIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGGELFHQIVRLTYFSEDLSRHVITQ 239 Query: 130 LALGLQYLHE-LEIAHRDIKCENVL 153 +A ++YLHE + HRDIK EN+L Sbjct: 240 VAHAIRYLHEDCGVVHRDIKPENLL 264 Score = 54.8 bits (126), Expect = 4e-08 Identities = 32/117 (27%), Positives = 63/117 (53%), Gaps = 7/117 (5%) Query: 348 DKLSILACKVIDTSTAPRDFVKKF------LPREIEMLIKLSHPHLVHTHSIFQRRYKYF 401 +K++I + +T PRD K+ + +E++++ ++ HP+++ Q Y+ Sbjct: 148 EKVAIKVVQRAQPNTDPRDPRKRQGVESHNILKEVQIMRRVKHPNIIQLLEFIQTPEYYY 207 Query: 402 IFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHE-LEIAHRDIKCENVL 457 + + + G+L +++ ED +R Q+A AI+Y+HE + HRDIK EN+L Sbjct: 208 LVLELADGGELFHQIVRLTYFSEDLSRHVITQVAHAIRYLHEDCGVVHRDIKPENLL 264 >SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1316 Score = 76.2 bits (179), Expect = 1e-14 Identities = 45/162 (27%), Positives = 84/162 (51%), Gaps = 5/162 (3%) Query: 9 SEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68 S + T + Y++ K + +G + VYL S++++ A K++ V + Sbjct: 554 SGKGTPSIQDYEIIKPISKGTFGTVYL----SRKNTTGEIYAIKVLRKVDMISKNQVANV 609 Query: 69 PREIDVLVRLNHPHLI-HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127 E VL+ + ++ FQ + Y+ M + GD S + + E+ A+++ Sbjct: 610 KAERAVLMAQEESAFVAKLYYAFQSRDYLYLVMEFMNGGDCASLLKSLYTIPESWAKIYI 669 Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSR 169 ++ALGL++LH L I HRDIK +N+L++ ++KL+DFG S+ Sbjct: 670 AEVALGLEHLHRLGIIHRDIKPDNILMSITGHLKLADFGLSQ 711 Score = 66.1 bits (154), Expect = 1e-11 Identities = 38/143 (26%), Positives = 74/143 (51%), Gaps = 4/143 (2%) Query: 394 FQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKC 453 FQ R ++ M +M GD + + E A+I+ ++AL ++++H L I HRDIK Sbjct: 632 FQSRDYLYLVMEFMNGGDCASLLKSLYTIPESWAKIYIAEVALGLEHLHRLGIIHRDIKP 691 Query: 454 ENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVW 513 +N+L++ ++KL+DFG +++ + + ++R + G + +P Q L P D Sbjct: 692 DNILMSITGHLKLADFGLSQLGLTTR--QLRLQK--GKNNILSPPSFQSPTALGDPGDNI 747 Query: 514 SLGIVVYVMLNRAMPFEDKHIKQ 536 + ++ A +++K KQ Sbjct: 748 ASSPLILPTSVSAFSYDEKSQKQ 770 Score = 43.2 bits (97), Expect = 1e-04 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 1/95 (1%) Query: 177 QPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ 236 QP + + G+ Y APE LRG D W+LG VLF L PF K++E Sbjct: 824 QPDAPKRFVGTPDYLAPETLRGSTQ-DDMVDWWALGCVLFEFLFGYPPFHAETPEKVFEN 882 Query: 237 QMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLR 271 + + S E ++ L+P+P R Sbjct: 883 ILANNIAWPDLEMYPCSEEALDLINGFLQPNPERR 917 Score = 39.9 bits (89), Expect = 0.001 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 1/94 (1%) Query: 488 FCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWK 547 F G+ Y APE L+G+ D W+LG V++ L PF + +++ + + N Sbjct: 831 FVGTPDYLAPETLRGSTQ-DDMVDWWALGCVLFEFLFGYPPFHAETPEKVFENILANNIA 889 Query: 548 FRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDI 581 + + S+ LI L+PN + RL DI Sbjct: 890 WPDLEMYPCSEEALDLINGFLQPNPERRLGFSDI 923 >SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1338 Score = 75.8 bits (178), Expect = 2e-14 Identities = 47/152 (30%), Positives = 77/152 (50%), Gaps = 5/152 (3%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKA-PKDFVVKFLPREIDVLVR 77 YK+ K + +GA+ VYL + + D A KI++ + K+ V+ ++ + Sbjct: 589 YKILKPISKGAFGSVYLAQKRTTGDY----FAIKILKKSNMIAKNQVINVRAERAILMSQ 644 Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137 P + ++ FQ K Y+ M Y GD S + G + + R + + L L L Sbjct: 645 GESPFVAKLYYTFQSKDYLYLVMEYLNGGDCGSLLKTMGVLDLDWIRTYIAETVLCLGDL 704 Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSR 169 H+ I HRDIK EN+L++ N ++KL+DFG SR Sbjct: 705 HDRGIIHRDIKPENLLISQNGHLKLTDFGLSR 736 Score = 63.3 bits (147), Expect = 1e-10 Identities = 45/161 (27%), Positives = 75/161 (46%), Gaps = 6/161 (3%) Query: 315 KHPPKRQGDILEGPTRESAF-RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLP 373 +HP IL+ P + AF VYLA+ R + IL A + Sbjct: 582 EHPSINDYKILK-PISKGAFGSVYLAQKRTTGDYFAIKILKKS---NMIAKNQVINVRAE 637 Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433 R I ++ + P + + FQ + ++ M Y+ GD + G + D R + + Sbjct: 638 RAI-LMSQGESPFVAKLYYTFQSKDYLYLVMEYLNGGDCGSLLKTMGVLDLDWIRTYIAE 696 Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARM 474 L + +H+ I HRDIK EN+L++ N ++KL+DFG +R+ Sbjct: 697 TVLCLGDLHDRGIIHRDIKPENLLISQNGHLKLTDFGLSRV 737 Score = 45.2 bits (102), Expect = 3e-05 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Query: 481 NEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQA 540 N+ S+ F G+ Y APE++ G P + K +D WSLG VV+ L PF + Q+ Q Sbjct: 850 NKDPSKRFIGTPDYIAPEVILGNPGI-KASDWWSLGCVVFEFLFGYPPFNAETPDQVFQN 908 Query: 541 QINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRL 576 + + + + S LI +L N NRL Sbjct: 909 ILARRINWPAEVFTAESSVALDLIDRLLCMNPANRL 944 Score = 45.2 bits (102), Expect = 3e-05 Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 1/97 (1%) Query: 181 SETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGK 240 S+ + G+ Y APE++ G P K +D WSLG V+F L PF+ ++++ + + Sbjct: 854 SKRFIGTPDYIAPEVILGNPGI-KASDWWSLGCVVFEFLFGYPPFNAETPDQVFQNILAR 912 Query: 241 KYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNV 277 + + + V + S ++ LL +P R A V Sbjct: 913 RINWPAEVFTAESSVALDLIDRLLCMNPANRLGANGV 949 >SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosaccharomyces pombe|chr 3|||Manual Length = 877 Score = 74.5 bits (175), Expect = 4e-14 Identities = 67/251 (26%), Positives = 119/251 (47%), Gaps = 17/251 (6%) Query: 1 MTDLKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAP 60 +T K + S + LLT+ +T +G G +++V+ E ++ + K+ P Sbjct: 550 LTSSKVSSSTSH-LLTRFRNVT-LLGSGEFSEVFQVEDPVEKTLKYAVKKLKV--KFSGP 605 Query: 61 KDFVVKFLPREIDVLVRLN-HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVS 119 K+ L +E+ + L H H++ + ++ Y+ + ENG L ++ + G +S Sbjct: 606 KER--NRLLQEVSIQRALKGHDHIVELMDSWEHGGFLYMQVELCENGSLDRFLEEQGQLS 663 Query: 120 E-NQARVWTR--QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDN 176 ++ RVW ++ALGLQ++H H D+K NV++T +K+ DFG + V Sbjct: 664 RLDEFRVWKILVEVALGLQFIHHKNYVHLDLKPANVMITFEGTLKIGDFGMA--SVWPVP 721 Query: 177 QPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLF-VMLNKSMPFDDTRMRKLYE 235 + + E G Y APE+L Y KP D++SLG+ +F N +P + +KL Sbjct: 722 RGMERE---GDCEYIAPEVLANHLY-DKPADIFSLGITVFEAAANIVLPDNGQSWQKLRS 777 Query: 236 QQMGKKYRFRS 246 + R S Sbjct: 778 GDLSDAPRLSS 788 Score = 68.5 bits (160), Expect = 3e-12 Identities = 45/164 (27%), Positives = 79/164 (48%), Gaps = 10/164 (6%) Query: 384 HPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQE-DQARIWTR--QLALAIQY 440 H H+V ++ ++ + E G L F+ ++G + D+ R+W ++AL +Q+ Sbjct: 624 HDHIVELMDSWEHGGFLYMQVELCENGSLDRFLEEQGQLSRLDEFRVWKILVEVALGLQF 683 Query: 441 MHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEIL 500 +H H D+K NV++T +K+ DFG A + + E G Y APE+L Sbjct: 684 IHHKNYVHLDLKPANVMITFEGTLKIGDFGMASVWPVPRGMERE-----GDCEYIAPEVL 738 Query: 501 QGTPYLPKPTDVWSLGIVVY-VMLNRAMPFEDKHIKQLHQAQIN 543 Y KP D++SLGI V+ N +P + ++L ++ Sbjct: 739 ANHLY-DKPADIFSLGITVFEAAANIVLPDNGQSWQKLRSGDLS 781 >SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Schizosaccharomyces pombe|chr 2|||Manual Length = 297 Score = 74.1 bits (174), Expect = 5e-14 Identities = 62/230 (26%), Positives = 111/230 (48%), Gaps = 21/230 (9%) Query: 17 KGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLV 76 + Y+ + +GEG Y VY ++ +A K I + + V REI +L Sbjct: 2 ENYQKVEKIGEGTYGVVY----KARHKLSGRIVAMKKIRL-EDESEGVPSTAIREISLLK 56 Query: 77 RLN----HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSY---ILKNGCVSENQARV--WT 127 +N + + + I ++K Y+ + + DL Y I + G S + V +T Sbjct: 57 EVNDENNRSNCVRLLDILHAESKLYLVFEFLDM-DLKKYMDRISETGATSLDPRLVQKFT 115 Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETY-CG 186 QL G+ + H I HRD+K +N+L+ N+KL+DFG +R S P+ + T+ Sbjct: 116 YQLVNGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLAR----SFGVPLRNYTHEIV 171 Query: 187 SMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF-DDTRMRKLYE 235 ++ Y APE+L G + D+WS+G + M+ +S F D+ + ++++ Sbjct: 172 TLWYRAPEVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLFPGDSEIDEIFK 221 Score = 66.5 bits (155), Expect = 1e-11 Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 7/143 (4%) Query: 398 YKYFIFMRYMERGDLLEFVLQRGAVQEDQARI--WTRQLALAIQYMHELEIAHRDIKCEN 455 Y F F+ M+ ++ + + GA D + +T QL + + H I HRD+K +N Sbjct: 81 YLVFEFLD-MDLKKYMDRISETGATSLDPRLVQKFTYQLVNGVNFCHSRRIIHRDLKPQN 139 Query: 456 VLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSL 515 +L+ N+KL+DFG AR L E +L Y APE+L G+ + D+WS+ Sbjct: 140 LLIDKEGNLKLADFGLAR-SFGVPLRNYTHEIV--TLWYRAPEVLLGSRHYSTGVDIWSV 196 Query: 516 GIVVYVMLNRAMPFE-DKHIKQL 537 G + M+ R+ F D I ++ Sbjct: 197 GCIFAEMIRRSPLFPGDSEIDEI 219 >SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizosaccharomyces pombe|chr 2|||Manual Length = 591 Score = 73.7 bits (173), Expect = 7e-14 Identities = 61/220 (27%), Positives = 111/220 (50%), Gaps = 27/220 (12%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y L + +GEG + +VY ++ ++D L ++ T K + F + + REI +L + Sbjct: 36 YHLMEKLGEGTFGEVYKSQ--RRKDGKVYALKRILMHTEK--EGFPITAI-REIKILKSI 90 Query: 79 NHPHLIHVHSI--------FQRKTKYYIFMRYTENGDLLSYILKNGCV--SENQARVWTR 128 H ++I + + +R+ Y+ Y ++ LS +L+N V +E Q + + + Sbjct: 91 KHENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHD--LSGLLENPSVKFTEPQIKCYMK 148 Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVE---SDNQPVL----S 181 QL G +YLH+ I HRD+K N+L+ + +K++DFG +R E ++ P L Sbjct: 149 QLFAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNR 208 Query: 182 ETYCGSMS---YAAPEILRGKPYCPKPTDLWSLGVVLFVM 218 Y G + Y +PE+L G+ D+WS+G ++ M Sbjct: 209 REYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEM 248 Score = 59.7 bits (138), Expect = 1e-09 Identities = 43/158 (27%), Positives = 77/158 (48%), Gaps = 14/158 (8%) Query: 377 EMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQ--EDQARIWTRQL 434 E +I LS +V +RR ++ YM+ L +L+ +V+ E Q + + +QL Sbjct: 93 ENIIPLSDMTVVRADKKHRRRGSIYMVTPYMDHD--LSGLLENPSVKFTEPQIKCYMKQL 150 Query: 435 ALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKK-------LNEIRSET 487 +Y+H+ I HRD+K N+L+ + +K++DFG AR+ ++ L Sbjct: 151 FAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRRE 210 Query: 488 FCGSLS---YTAPEILQGTPYLPKPTDVWSLGIVVYVM 522 + G + Y +PE+L G D+WS+G ++ M Sbjct: 211 YTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEM 248 >SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizosaccharomyces pombe|chr 2|||Manual Length = 381 Score = 73.7 bits (173), Expect = 7e-14 Identities = 47/180 (26%), Positives = 91/180 (50%), Gaps = 15/180 (8%) Query: 369 KKFLPREIEMLIKLSHPHLV------HTHSIFQRRYKYFIFMRYMER---GDLLEFVLQR 419 K++ RE++++ +SHP+++ HTH+ + + + YM D+ + +R Sbjct: 60 KRYKNRELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRR 119 Query: 420 GAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNV-KLSDFGFARMCVDK 478 ++ +++ QL A+ Y+H + HRDIK +N+L+ + KL DFG A++ V Sbjct: 120 KSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPS 179 Query: 479 KLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLG-IVVYVMLNRAMPFEDKHIKQL 537 + N ++ S Y APE++ G + DVWS ++ + + R + D ++QL Sbjct: 180 EPN----VSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQL 235 Score = 66.1 bits (154), Expect = 1e-11 Identities = 45/160 (28%), Positives = 79/160 (49%), Gaps = 14/160 (8%) Query: 66 KFLPREIDVLVRLNHPHLI------HVHSIFQRKTKYYIFMRY---TENGDLLSYILKNG 116 ++ RE+ ++ ++HP++I H H+ + +T + + Y T D+ Y + Sbjct: 61 RYKNRELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRK 120 Query: 117 CVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNV-KLSDFGFSRFCVESD 175 + +++ QL L YLH + HRDIK +N+L+ + KL DFG ++ V S Sbjct: 121 SIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPS- 179 Query: 176 NQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVL 215 +P +S Y S Y APE++ G + D+WS V+ Sbjct: 180 -EPNVS--YICSRYYRAPELVFGATHYTTKIDVWSAACVI 216 >SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccharomyces pombe|chr 2|||Manual Length = 605 Score = 72.5 bits (170), Expect = 2e-13 Identities = 71/266 (26%), Positives = 110/266 (41%), Gaps = 19/266 (7%) Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84 +G+G Y VY + T+A K I + F + E+D+L + P+++ Sbjct: 326 LGKGNYGVVY----KALHQPTGVTMALKEIRLSLEEATF--NQIIMELDILHKAVSPYIV 379 Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL-HELEIA 143 + F + +I M Y + G + + G E + GL+ L E I Sbjct: 380 DFYGAFFVEGSVFICMEYMDAGSM-DKLYAGGIKDEGVLARTAYAVVQGLKTLKEEHNII 438 Query: 144 HRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR-GKPYC 202 HRD+K NVL+ +N VKL DFG S V S +S+T G SY APE +R G P Sbjct: 439 HRDVKPTNVLVNSNGQVKLCDFGVSGNLVAS-----ISKTNIGCQSYMAPERIRVGGPTN 493 Query: 203 PKPT-----DLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257 T D+WSLG+ + M + P+ ++ Q + S E + Sbjct: 494 GVLTYTVQADVWSLGLTILEMALGAYPYPPESYTSIFAQLSAICDGDPPSLPDSFSPEAR 553 Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWI 283 V L +P LR + + W+ Sbjct: 554 DFVNKCLNKNPSLRPDYHELANHPWL 579 Score = 66.9 bits (156), Expect = 8e-12 Identities = 61/224 (27%), Positives = 99/224 (44%), Gaps = 21/224 (9%) Query: 375 EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQL 434 E+++L K P++V + F FI M YM+ G + + L G ++++ + R Sbjct: 366 ELDILHKAVSPYIVDFYGAFFVEGSVFICMEYMDAGSMDK--LYAGGIKDEG--VLARTA 421 Query: 435 ALAIQYMHELE----IAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCG 490 +Q + L+ I HRD+K NVL+ +N VKL DFG V L S+T G Sbjct: 422 YAVVQGLKTLKEEHNIIHRDVKPTNVLVNSNGQVKLCDFG-----VSGNLVASISKTNIG 476 Query: 491 SLSYTAPEILQ------GTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINK 544 SY APE ++ G DVWSLG+ + M A P+ + + AQ++ Sbjct: 477 CQSYMAPERIRVGGPTNGVLTYTVQADVWSLGLTILEMALGAYPYPPESYTSIF-AQLSA 535 Query: 545 NWKFRSRYI-DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587 + D+ S + + L N R +++ N W+ Sbjct: 536 ICDGDPPSLPDSFSPEARDFVNKCLNKNPSLRPDYHELANHPWL 579 >SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 3|||Manual Length = 781 Score = 72.5 bits (170), Expect = 2e-13 Identities = 64/230 (27%), Positives = 107/230 (46%), Gaps = 20/230 (8%) Query: 15 LTKGYKL---TKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKD----FVVKF 67 L+ YKL TK +G GA A + + + +++ K+ KA + ++ K Sbjct: 439 LSAKYKLVDETKDMGSGATAVIRIVTLKNPKENEKNLRFAVKAYRRKADDETDGQYIAK- 497 Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIF-------MRYTENGDLLSYIL-KNGCVS 119 L E V R+ HP+++ + + + ++ M + GDLLS I ++ + Sbjct: 498 LASEWLVQCRMEHPNVVKSYDLCIDSHIFPLYSDTWCAVMDFCPRGDLLSLIEDRHDRLG 557 Query: 120 ENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFG-FSRFCVESDNQP 178 + +Q+ GL Y+H IAHRDIK EN+L++ ++++DFG C D+ Sbjct: 558 KKDFECMIKQILRGLNYIHSQGIAHRDIKPENILISEYGVLRITDFGACDVLCNPGDDIT 617 Query: 179 VL---SETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 + S GS Y APEIL Y D+WS +VL + ++ PF Sbjct: 618 AVESKSMGIFGSDPYMAPEILTPGSYNAFFADMWSTAIVLHCLYFRTYPF 667 Score = 69.7 bits (163), Expect = 1e-12 Identities = 58/224 (25%), Positives = 100/224 (44%), Gaps = 13/224 (5%) Query: 336 VYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQ 395 V L + KN + ++ A + ++ K L E + ++ HP++V ++ + Sbjct: 463 VTLKNPKENEKNLRFAVKAYRRKADDETDGQYIAK-LASEWLVQCRMEHPNVVKSYDLCI 521 Query: 396 RRYKYFIF-------MRYMERGDLLEFVLQR-GAVQEDQARIWTRQLALAIQYMHELEIA 447 + + ++ M + RGDLL + R + + +Q+ + Y+H IA Sbjct: 522 DSHIFPLYSDTWCAVMDFCPRGDLLSLIEDRHDRLGKKDFECMIKQILRGLNYIHSQGIA 581 Query: 448 HRDIKCENVLLTANQNVKLSDFGFAR-MC---VDKKLNEIRSETFCGSLSYTAPEILQGT 503 HRDIK EN+L++ ++++DFG +C D E +S GS Y APEIL Sbjct: 582 HRDIKPENILISEYGVLRITDFGACDVLCNPGDDITAVESKSMGIFGSDPYMAPEILTPG 641 Query: 504 PYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWK 547 Y D+WS IV++ + R PF A+ K W+ Sbjct: 642 SYNAFFADMWSTAIVLHCLYFRTYPFRKASQNDQLYAKYCKAWR 685 >SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase Srb10 |Schizosaccharomyces pombe|chr 1|||Manual Length = 352 Score = 72.1 bits (169), Expect = 2e-13 Identities = 61/226 (26%), Positives = 100/226 (44%), Gaps = 16/226 (7%) Query: 18 GYKLTKFVGEGAYAKVYLTEYSSKEDSH----KSTLACKIIETAKAPKDFVVKFLPREID 73 GYK+ F+ G Y KVY S+ D K A ++ A + V + RE+ Sbjct: 4 GYKIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMM 63 Query: 74 VLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQ-------ARVW 126 + + H +++ + + + + Y E+ DLL I + Q + +W Sbjct: 64 LCREIQHENIVSLVQVLLKDGTISMVFEYAEH-DLLQIIHFHSRSRTRQIPPSILKSILW 122 Query: 127 TRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCG 186 Q+ G+ YLHE I HRD+K N+++TA VK+ D G R + S+ Sbjct: 123 --QIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFYSSDRVVV 180 Query: 187 SMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF--DDTRM 230 ++ Y APE+L G D+W++G + ML S F D+ +M Sbjct: 181 TIWYRAPELLLGAHDYTPAIDVWAIGCIYGEMLALSPLFKGDEIKM 226 Score = 68.5 bits (160), Expect = 3e-12 Identities = 49/181 (27%), Positives = 83/181 (45%), Gaps = 6/181 (3%) Query: 360 TSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVL-- 417 +S A + V + RE+ + ++ H ++V + + + Y E DLL+ + Sbjct: 46 SSNAQQTGVSQSAIREMMLCREIQHENIVSLVQVLLKDGTISMVFEYAEH-DLLQIIHFH 104 Query: 418 QRGAVQEDQARIWTR---QLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARM 474 R ++ I Q+ + Y+HE I HRD+K N+++TA VK+ D G R+ Sbjct: 105 SRSRTRQIPPSILKSILWQIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRL 164 Query: 475 CVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHI 534 D L S+ ++ Y APE+L G DVW++G + ML + F+ I Sbjct: 165 IRDPILPFYSSDRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEMLALSPLFKGDEI 224 Query: 535 K 535 K Sbjct: 225 K 225 >SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 363 Score = 72.1 bits (169), Expect = 2e-13 Identities = 41/93 (44%), Positives = 53/93 (56%), Gaps = 6/93 (6%) Query: 133 GLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAA 192 GL YLH+ +I HRDIK N+LLT+ VKL DFG S V S L+ T+ G+ Y A Sbjct: 193 GLSYLHDRKIIHRDIKPSNILLTSKGQVKLCDFGVSGELVNS-----LAGTFTGTSYYMA 247 Query: 193 PEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 PE + G Y +D+WSLG+ L + PF Sbjct: 248 PERISGGSYTIS-SDIWSLGLTLMEVALNRFPF 279 Score = 67.3 bits (157), Expect = 6e-12 Identities = 58/177 (32%), Positives = 87/177 (49%), Gaps = 20/177 (11%) Query: 363 APRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYK--YFIFMRYMERGDLLEFVLQRG 420 AP ++K L RE+++ + P++V + + I M Y G L + + +R Sbjct: 113 APNTALQKQLLRELKINRSCTSPYIVKYYGACYNNAECQLNIAMEYCGAGSL-DAIYKR- 170 Query: 421 AVQEDQARIWTRQLAL-------AIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFAR 473 V+ R R L + Y+H+ +I HRDIK N+LLT+ VKL DFG Sbjct: 171 -VRSQGGRTGERPLGKIAFGVLSGLSYLHDRKIIHRDIKPSNILLTSKGQVKLCDFG--- 226 Query: 474 MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGI-VVYVMLNRAMPF 529 V +L + TF G+ Y APE + G Y +D+WSLG+ ++ V LNR PF Sbjct: 227 --VSGELVNSLAGTFTGTSYYMAPERISGGSYTIS-SDIWSLGLTLMEVALNR-FPF 279 >SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating kinase Crk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 335 Score = 70.5 bits (165), Expect = 7e-13 Identities = 58/209 (27%), Positives = 96/209 (45%), Gaps = 14/209 (6%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y + VGEG YA V+L KE + + +A K I+ + + L REI L Sbjct: 11 YVKERKVGEGTYAVVFLGR--QKETNRR--VAIKKIKVGQFKDGIDISAL-REIKFLRES 65 Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARV--WTRQLALGLQY 136 H ++I + +F K+ I + + ++ L ++K+ + A + W L GL + Sbjct: 66 RHDNVIELVDVFSTKSNLNIILEFLDSD--LEMLIKDKFIVFQPAHIKSWMVMLLRGLHH 123 Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196 +H I HRD+K N+L++++ +KL+DFG SR P + Y PE+ Sbjct: 124 IHSRFILHRDLKPNNLLISSDGVLKLADFGLSR----DFGTPSHMSHQVITRWYRPPELF 179 Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 G D+WS+G + F L P+ Sbjct: 180 MGCRSYGTGVDMWSVGCI-FAELMLRTPY 207 Score = 54.4 bits (125), Expect = 5e-08 Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 6/153 (3%) Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAV-QEDQARIWTR 432 REI+ L + H +++ +F + I + +++ DL + + V Q + W Sbjct: 57 REIKFLRESRHDNVIELVDVFSTKSNLNIILEFLD-SDLEMLIKDKFIVFQPAHIKSWMV 115 Query: 433 QLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSL 492 L + ++H I HRD+K N+L++++ +KL+DFG +R D S + Sbjct: 116 MLLRGLHHIHSRFILHRDLKPNNLLISSDGVLKLADFGLSR---DFGTPSHMSHQVI-TR 171 Query: 493 SYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNR 525 Y PE+ G D+WS+G + ++ R Sbjct: 172 WYRPPELFMGCRSYGTGVDMWSVGCIFAELMLR 204 >SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizosaccharomyces pombe|chr 2|||Manual Length = 872 Score = 69.7 bits (163), Expect = 1e-12 Identities = 72/273 (26%), Positives = 130/273 (47%), Gaps = 32/273 (11%) Query: 21 LTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL-N 79 + K++ EG ++ VYL + +SK D T +++ +P + ++F+ EI+ + L + Sbjct: 27 IEKYIAEGGFSHVYLVQTNSKTDGSPIT---AVLKRMYSPDENALRFVKTEIETMELLKS 83 Query: 80 HPHLI-HVHS-IFQRKT-------KYYIFMRYTENGDLLSYILK--NGCVSENQARVWTR 128 +PH++ ++ S IF + + + M Y G L+ ++ + +SE++ Sbjct: 84 NPHVVSYIDSCIFPLEKAGVNTGFEILLLMEYCAGGGLIDFMNQRLQTRLSEHEVLKIIS 143 Query: 129 QLALGLQYLHELE--IAHRDIKCENVLLTANFNVKLSDFGF---SRFCVESDNQPVLSET 183 + G+ LH L + HRD+K ENVLL+ N KL DFG E+ ++ E Sbjct: 144 DIVQGVASLHYLRPPLIHRDLKVENVLLSFN-TFKLCDFGSVTEPMHAAENSSEIQALEK 202 Query: 184 YCGSMS---YAAPEI--LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQM 238 + + Y APE+ L + +D+W+LGV+L+ + + PF+ + + Sbjct: 203 SINTFTTYQYRAPEMINLYSGLGIDEKSDMWALGVLLYKLCYYTTPFETQGPNAI----L 258 Query: 239 GKKYRFRSRVASILSLECKTVVKHLLEPDPGLR 271 Y F SL K V+ LL+P+P LR Sbjct: 259 TASYSFPPFPPYSHSL--KNVIIALLQPNPCLR 289 Score = 60.9 bits (141), Expect = 5e-10 Identities = 75/270 (27%), Positives = 123/270 (45%), Gaps = 35/270 (12%) Query: 336 VYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKL-SHPHLVH--THS 392 VYL + SK D I A V+ +P + +F+ EIE + L S+PH+V Sbjct: 39 VYLVQTN--SKTDGSPITA--VLKRMYSPDENALRFVKTEIETMELLKSNPHVVSYIDSC 94 Query: 393 IFQRR-------YKYFIFMRYMERGDLLEFVLQR--GAVQEDQARIWTRQLALAIQYMHE 443 IF ++ + M Y G L++F+ QR + E + + + +H Sbjct: 95 IFPLEKAGVNTGFEILLLMEYCAGGGLIDFMNQRLQTRLSEHEVLKIISDIVQGVASLHY 154 Query: 444 LE--IAHRDIKCENVLLTANQNVKLSDFGFAR--MCVDKKLNEIRS-----ETFCGSLSY 494 L + HRD+K ENVLL+ N KL DFG M + +EI++ TF + Y Sbjct: 155 LRPPLIHRDLKVENVLLSFN-TFKLCDFGSVTEPMHAAENSSEIQALEKSINTFT-TYQY 212 Query: 495 TAPEI--LQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRY 552 APE+ L + + +D+W+LG+++Y + PFE Q A + ++ F Sbjct: 213 RAPEMINLYSGLGIDEKSDMWALGVLLYKLCYYTTPFE----TQGPNAILTASYSFPP-- 266 Query: 553 IDTISDNCKRLIGLMLEPNHQNRLKIYDIV 582 S + K +I +L+PN R I+ ++ Sbjct: 267 FPPYSHSLKNVIIALLQPNPCLRPNIFQLM 296 >SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase kinase Win1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1436 Score = 69.3 bits (162), Expect = 2e-12 Identities = 55/202 (27%), Positives = 96/202 (47%), Gaps = 30/202 (14%) Query: 365 RDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQE 424 R +K+ + E+ +L HP++V + I R K IFM + L EF L+ G +++ Sbjct: 1160 RPMIKR-IKGEMLVLELFDHPNVVSYYGIEVHREKVNIFMELCQGSSLFEF-LRYGRIED 1217 Query: 425 DQA-RIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMC------VD 477 + +++ QL + Y+H ++H+D+K EN+L N +K +DFG A+M + Sbjct: 1218 ELVIQVYVLQLLEGLAYIHSCGVSHQDVKPENILFDHNGIMKFTDFGSAKMSGSASTKIF 1277 Query: 478 KKLNEIRSETF------------------CGSLSYTAPEILQGTP-YLPKPTDVWSLGIV 518 ++L + E F G+ +Y APE++ G P D+WSLG V Sbjct: 1278 EQLTQQEEEEFEKDSEFLQHLDQNRGYSLTGTPTYMAPELILGNPSERVGAMDIWSLGCV 1337 Query: 519 VYVMLNRAMPFE--DKHIKQLH 538 + M + P+ D H ++ Sbjct: 1338 IVEMATGSPPWPRLDNHFSLMY 1359 Score = 65.7 bits (153), Expect = 2e-11 Identities = 50/187 (26%), Positives = 87/187 (46%), Gaps = 25/187 (13%) Query: 64 VVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQA 123 ++K + E+ VL +HP+++ + I + K IFM + L ++ E Sbjct: 1162 MIKRIKGEMLVLELFDHPNVVSYYGIEVHREKVNIFMELCQGSSLFEFLRYGRIEDELVI 1221 Query: 124 RVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFC------------ 171 +V+ QL GL Y+H ++H+D+K EN+L N +K +DFG ++ Sbjct: 1222 QVYVLQLLEGLAYIHSCGVSHQDVKPENILFDHNGIMKFTDFGSAKMSGSASTKIFEQLT 1281 Query: 172 ------VESDNQPV--LSE----TYCGSMSYAAPEILRGKP-YCPKPTDLWSLGVVLFVM 218 E D++ + L + + G+ +Y APE++ G P D+WSLG V+ M Sbjct: 1282 QQEEEEFEKDSEFLQHLDQNRGYSLTGTPTYMAPELILGNPSERVGAMDIWSLGCVIVEM 1341 Query: 219 LNKSMPF 225 S P+ Sbjct: 1342 ATGSPPW 1348 >SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosaccharomyces pombe|chr 3|||Manual Length = 477 Score = 66.9 bits (156), Expect = 8e-12 Identities = 59/225 (26%), Positives = 99/225 (44%), Gaps = 19/225 (8%) Query: 33 VYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLN------HPHLIHV 86 ++ T S+ + + T A KII + + K +E+ +L RL H+IH Sbjct: 169 MFSTVVSALDRNRNQTFAIKIIRN----NEVMYKEGLKEVSILERLQAADREGKQHIIHY 224 Query: 87 HSIFQRKTKY-YIFMRYTEN-GDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144 F K +F + N D+L +N +S R++ Q+ + L L + + H Sbjct: 225 ERHFMHKNHLCMVFEMLSLNLRDILKKFGRNVGLSIKAVRLYAYQMFMALDLLKQCNVIH 284 Query: 145 RDIKCENVLLTANFNV-KLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCP 203 DIK +N+L+ N+ K+ D G + E++ P Y S Y APEI+ G PY Sbjct: 285 SDIKPDNMLVNEKRNILKICDLGSASDASENEITP-----YLVSRFYRAPEIILGFPY-S 338 Query: 204 KPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248 P D WS+G L+ + + F ++ M K +F ++ Sbjct: 339 CPIDTWSVGCSLYELYTGQILFPGRTNNQMLRYMMECKGKFSHKM 383 Score = 60.1 bits (139), Expect = 1e-09 Identities = 44/171 (25%), Positives = 80/171 (46%), Gaps = 9/171 (5%) Query: 386 HLVHTHSIFQRR-YKYFIF-MRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHE 443 H++H F + + +F M + D+L+ + + R++ Q+ +A+ + + Sbjct: 220 HIIHYERHFMHKNHLCMVFEMLSLNLRDILKKFGRNVGLSIKAVRLYAYQMFMALDLLKQ 279 Query: 444 LEIAHRDIKCENVLLTANQNV-KLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQG 502 + H DIK +N+L+ +N+ K+ D G A D NEI + S Y APEI+ G Sbjct: 280 CNVIHSDIKPDNMLVNEKRNILKICDLGSAS---DASENEI--TPYLVSRFYRAPEIILG 334 Query: 503 TPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553 PY P D WS+G +Y + + F + Q+ + + KF + + Sbjct: 335 FPY-SCPIDTWSVGCSLYELYTGQILFPGRTNNQMLRYMMECKGKFSHKML 384 >SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 65.7 bits (153), Expect = 2e-11 Identities = 55/198 (27%), Positives = 93/198 (46%), Gaps = 20/198 (10%) Query: 395 QRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIW--TRQLALAIQYMHELE--IAHRD 450 + +++ + + Y G L++F+ R V+ + I + A+ MH L+ + HRD Sbjct: 107 KNQFEVLVLLEYCPCGGLIDFLNTRLQVRLSEQEILKIASDVTEAVAVMHYLKPPLIHRD 166 Query: 451 IKCENVLLTANQNVKLSDFGF-------ARMCVDKKLNEIRSETFCGSLSYTAPEILQGT 503 +K ENVLL A + KL DFG A+ + K E E F + Y PE++ Sbjct: 167 LKIENVLLAAPNSYKLCDFGSACHPIPGAKTAAEAKQLEYDIEKFT-TWQYRCPEMINVH 225 Query: 504 P--YLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCK 561 + + +D+W+LG++ Y + PFE + + A +N ++ F + SD K Sbjct: 226 KGFGIDEKSDIWALGVLFYKLCYYTTPFEHQGL----AAIMNVSYAFPT--FPPYSDRLK 279 Query: 562 RLIGLMLEPNHQNRLKIY 579 RLI +L+ R IY Sbjct: 280 RLISTLLQQYPWQRPNIY 297 Score = 41.1 bits (92), Expect = 5e-04 Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 14/142 (9%) Query: 98 IFMRYTENGDLLSYILKNGCV--SENQARVWTRQLALGLQYLHELE--IAHRDIKCENVL 153 + + Y G L+ ++ V SE + + + +H L+ + HRD+K ENVL Sbjct: 114 VLLEYCPCGGLIDFLNTRLQVRLSEQEILKIASDVTEAVAVMHYLKPPLIHRDLKIENVL 173 Query: 154 LTANFNVKLSDFGF-------SRFCVESDNQPVLSETYCGSMSYAAPEILR-GKPY-CPK 204 L A + KL DFG ++ E+ E + + Y PE++ K + + Sbjct: 174 LAAPNSYKLCDFGSACHPIPGAKTAAEAKQLEYDIEKFT-TWQYRCPEMINVHKGFGIDE 232 Query: 205 PTDLWSLGVVLFVMLNKSMPFD 226 +D+W+LGV+ + + + PF+ Sbjct: 233 KSDIWALGVLFYKLCYYTTPFE 254 >SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosaccharomyces pombe|chr 2|||Manual Length = 559 Score = 65.7 bits (153), Expect = 2e-11 Identities = 55/209 (26%), Positives = 103/209 (49%), Gaps = 16/209 (7%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y + + +G+G++ VYL + K ++ T+A K ++ + PK RE L ++ Sbjct: 21 YLVKQKLGDGSFGTVYLAQRKEKNGLYE-TVAVKKLKNSSKPKPKHELLKLRESLALRKI 79 Query: 79 N-HPHLIHVHSIFQRKTK-YYIFMRYTENGDLLSYILKNGCV-SENQARVWTRQLALGLQ 135 + HP LI + F + ++ M + + + + G + ++ A Q+ G++ Sbjct: 80 SKHPCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISGIE 139 Query: 136 YLHELEIAHRDIKCENVL--------LTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187 ++H+ HRDIK EN+L +++ +++KL DFG +R V SD L+E Y + Sbjct: 140 HIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARPSVSSD---PLTE-YVST 195 Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLF 216 Y APE+L DL++ G ++F Sbjct: 196 RWYRAPELLLRSGSYNHSVDLYAFGCIVF 224 Score = 59.3 bits (137), Expect = 2e-09 Identities = 56/197 (28%), Positives = 93/197 (47%), Gaps = 19/197 (9%) Query: 336 VYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLS-HPHLVHTHSIF 394 VYLA+ + KN +A K + S+ P+ + RE L K+S HP L+ F Sbjct: 35 VYLAQRKE--KNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRKISKHPCLIDLLETF 92 Query: 395 QRRYK-YFIFMRYMERGDLLEFVLQRGAV-QEDQARIWTRQLALAIQYMHELEIAHRDIK 452 Y+ F+ M +M+ F ++G + ++ A Q+ I+++H+ HRDIK Sbjct: 93 MDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISGIEHIHKHGFMHRDIK 152 Query: 453 CENVL--------LTANQNVKLSDFGFARMCVDK-KLNEIRSETFCGSLSYTAPEILQGT 503 EN+L +++ ++KL DFG AR V L E S + Y APE+L + Sbjct: 153 PENILVKRISPKPISSRYSIKLGDFGLARPSVSSDPLTEYVSTRW-----YRAPELLLRS 207 Query: 504 PYLPKPTDVWSLGIVVY 520 D+++ G +V+ Sbjct: 208 GSYNHSVDLYAFGCIVF 224 >SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity protein kinase Mph1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 678 Score = 65.7 bits (153), Expect = 2e-11 Identities = 41/120 (34%), Positives = 63/120 (52%), Gaps = 14/120 (11%) Query: 428 RIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSET 487 R++ Q+ A+Q +H+ I H D+K N LL N+KL DFG A+ + I ++ Sbjct: 420 RMYWEQMLEAVQVVHDQNIVHSDLKPANFLLVEG-NLKLIDFGIAK-AIGNDTTNIHRDS 477 Query: 488 FCGSLSYTAPEIL--------QGTPY--LPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQL 537 G+++Y APE L G L +P+DVWSLG ++Y M+ PF H+K + Sbjct: 478 HIGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQMVYGRAPF--AHLKMI 535 Score = 62.5 bits (145), Expect = 2e-10 Identities = 40/136 (29%), Positives = 71/136 (52%), Gaps = 14/136 (10%) Query: 107 DLLSYILKN--GCVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSD 164 DL + ++KN ++ N R++ Q+ +Q +H+ I H D+K N LL N+KL D Sbjct: 401 DLANLLMKNMKKPINLNFIRMYWEQMLEAVQVVHDQNIVHSDLKPANFLLVEG-NLKLID 459 Query: 165 FGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGK----------PYCPKPTDLWSLGVV 214 FG ++ + +D + +++ G+++Y APE L +P+D+WSLG + Sbjct: 460 FGIAK-AIGNDTTNIHRDSHIGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCI 518 Query: 215 LFVMLNKSMPFDDTRM 230 L+ M+ PF +M Sbjct: 519 LYQMVYGRAPFAHLKM 534 >SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gcn2 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1576 Score = 64.1 bits (149), Expect = 6e-11 Identities = 67/202 (33%), Positives = 97/202 (48%), Gaps = 22/202 (10%) Query: 97 YIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTA 156 YI M Y E L I+++ + R++ RQ+ L Y+H + HRD+K N+ L Sbjct: 725 YIQMEYCEKLSLQD-IIRDKIPVDEMWRLF-RQILEALAYIHSRGMMHRDLKPGNIFLDE 782 Query: 157 NFNVKLSDFGFS----RFCVESD---NQPVLSE---TYCGSMSYAAPEIL---RGKPYCP 203 N NVKL DFG + + +D N+ E T G+ Y APE+L G Y Sbjct: 783 NRNVKLGDFGLATENENYQDNNDKWKNRQSADEDLTTGVGTALYVAPELLSRRNGVRYDA 842 Query: 204 KPTDLWSLGVVLFVMLNKSMPFDDTRMR-KLYEQQMGKKYRFRSRVA-SILSLECKTVVK 261 K D++SLG++LF M M F + R ++ + F S S S E K V+ Sbjct: 843 K-VDMYSLGIILFEM---CMTFSTSMERIRIIDTIRSPSISFPSTFPFSRASHEFK-VIH 897 Query: 262 HLLEPDPGLRHSATNVLDSEWI 283 LL+ DP R S+ +L+SE I Sbjct: 898 CLLQHDPTKRPSSQELLESEAI 919 Score = 59.7 bits (138), Expect = 1e-09 Identities = 47/135 (34%), Positives = 71/135 (52%), Gaps = 16/135 (11%) Query: 401 FIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTA 460 +I M Y E+ L + + + V E R++ RQ+ A+ Y+H + HRD+K N+ L Sbjct: 725 YIQMEYCEKLSLQDIIRDKIPVDE-MWRLF-RQILEALAYIHSRGMMHRDLKPGNIFLDE 782 Query: 461 NQNVKLSDFGFA------RMCVDKKLNEIRSE----TFCGSLSYTAPEIL---QGTPYLP 507 N+NVKL DFG A + DK N ++ T G+ Y APE+L G Y Sbjct: 783 NRNVKLGDFGLATENENYQDNNDKWKNRQSADEDLTTGVGTALYVAPELLSRRNGVRYDA 842 Query: 508 KPTDVWSLGIVVYVM 522 K D++SLGI+++ M Sbjct: 843 K-VDMYSLGIILFEM 856 Score = 42.7 bits (96), Expect = 2e-04 Identities = 30/135 (22%), Positives = 60/135 (44%), Gaps = 9/135 (6%) Query: 398 YKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVL 457 ++ ++ Y + L + + + R ++ + + +H L I+H+ + +NV+ Sbjct: 322 WRLYVLQEYSPKFTLFSLLQTVLTLDVETVRAFSNNILEGLAELHRLGISHKSLHLDNVV 381 Query: 458 LTANQN---VKLSDFGFARMCVDKKLN---EIRSETFCGSL--SYTAPEILQGT-PYLPK 508 L + + KL DFGF R D + I S++ L PE+ + + + Sbjct: 382 LFHSGHRTFAKLMDFGFTRTLRDMNASHPFNINSQSITNILPEGLYPPEVSESSFAAASR 441 Query: 509 PTDVWSLGIVVYVML 523 TD+W G++V ML Sbjct: 442 KTDIWCFGLLVLQML 456 Score = 42.3 bits (95), Expect = 2e-04 Identities = 39/170 (22%), Positives = 77/170 (45%), Gaps = 15/170 (8%) Query: 65 VKFLPREIDVLVRLNHPHLIHVHSI-FQRKTK-----YYIFMRYTENGDLLSYILKNGCV 118 ++ L E++ L + H L ++ +R+T+ Y+ Y+ L S + + Sbjct: 287 IQELEYELESLKVIRHDLLASIYEYQLERETRGYGWRLYVLQEYSPKFTLFSLLQTVLTL 346 Query: 119 SENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFN---VKLSDFGFSRFCVESD 175 R ++ + GL LH L I+H+ + +NV+L + + KL DFGF+R + + Sbjct: 347 DVETVRAFSNNILEGLAELHRLGISHKSLHLDNVVLFHSGHRTFAKLMDFGFTRTLRDMN 406 Query: 176 -NQP--VLSETYCGSM--SYAAPEILRGK-PYCPKPTDLWSLGVVLFVML 219 + P + S++ + PE+ + TD+W G+++ ML Sbjct: 407 ASHPFNINSQSITNILPEGLYPPEVSESSFAAASRKTDIWCFGLLVLQML 456 >SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizosaccharomyces pombe|chr 2|||Manual Length = 953 Score = 62.9 bits (146), Expect = 1e-10 Identities = 62/225 (27%), Positives = 103/225 (45%), Gaps = 27/225 (12%) Query: 375 EIEMLIKLS-HPHLVH------THSIFQRRYKYFIFMRYMERGDLLEFV---LQRGAVQE 424 EIE + +L H H+V+ +S + RY+ ++ M + G L++F+ LQ + Sbjct: 101 EIETMKRLKGHRHIVNYIDSSALYSKSENRYEVYLLMEFCAGGGLIDFMNTRLQHRLTEG 160 Query: 425 DQARIWTRQLALAIQYMHELE--IAHRDIKCENVLLTANQNVKLSDFGFA------RMCV 476 + +I + A+ MH L+ + HRD+K ENVLL A + KL DFG A Sbjct: 161 EILKILA-DVCDAVAAMHYLDPPLIHRDLKIENVLLVAPNSYKLCDFGSACEPLAPATTP 219 Query: 477 DKKLNEIRSETFCGSLSYTAPEI--LQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHI 534 D + ++ + Y APE+ + + + +D+W++G++ Y + PFE Sbjct: 220 DTIMFLEQNIAAYTTPQYRAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYYTTPFE---- 275 Query: 535 KQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIY 579 Q+ + I K F SD KR I L+ +R IY Sbjct: 276 -QVGNSAILKA-SFSFPPFPRYSDRMKRFIATCLQEQPSHRPNIY 318 Score = 51.6 bits (118), Expect = 3e-07 Identities = 47/225 (20%), Positives = 103/225 (45%), Gaps = 27/225 (12%) Query: 21 LTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLN- 79 + +++ EG ++ VYL +++ +++ P ++ + EI+ + RL Sbjct: 59 IQRYLSEGGFSHVYLALLENEKPF--------VLKRIYVPDKTALQLVHGEIETMKRLKG 110 Query: 80 HPHLIH------VHSIFQRKTKYYIFMRYTENGDLLSYILKN--GCVSENQARVWTRQLA 131 H H+++ ++S + + + Y+ M + G L+ ++ ++E + + Sbjct: 111 HRHIVNYIDSSALYSKSENRYEVYLLMEFCAGGGLIDFMNTRLQHRLTEGEILKILADVC 170 Query: 132 LGLQYLHELE--IAHRDIKCENVLLTANFNVKLSDFGFS----RFCVESDNQPVLSETYC 185 + +H L+ + HRD+K ENVLL A + KL DFG + D L + Sbjct: 171 DAVAAMHYLDPPLIHRDLKIENVLLVAPNSYKLCDFGSACEPLAPATTPDTIMFLEQNIA 230 Query: 186 G--SMSYAAPEI--LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFD 226 + Y APE+ + + + +D+W++GV+ + + + PF+ Sbjct: 231 AYTTPQYRAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYYTTPFE 275 >SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyces pombe|chr 1|||Manual Length = 349 Score = 62.9 bits (146), Expect = 1e-10 Identities = 53/206 (25%), Positives = 94/206 (45%), Gaps = 14/206 (6%) Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACK-IIETAKAPKDFVVKFLPREID 73 +T Y + +G GA+ V S+K+ +A K I++ P + K RE+ Sbjct: 16 ITTRYSDLQPIGMGAFGLVC----SAKDQLTGMNVAVKKIMKPFSTP--VLAKRTYRELK 69 Query: 74 VLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALG 133 +L L H ++I + IF + F+ DL +L + + + + Q+ G Sbjct: 70 LLKHLRHENIISLSDIFISPFEDIYFVTELLGTDL-HRLLTSRPLETQFIQYFLYQILRG 128 Query: 134 LQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAP 193 L+++H + HRD+K N+L+ N ++K+ DFG +R P ++ Y + Y AP Sbjct: 129 LKFVHSAGVIHRDLKPSNILINENCDLKICDFGLARI-----QDPQMT-GYVSTRYYRAP 182 Query: 194 EILRGKPYCPKPTDLWSLGVVLFVML 219 EI+ D+WS G + M+ Sbjct: 183 EIMLTWQKYNVEVDIWSAGCIFAEMI 208 Score = 62.5 bits (145), Expect = 2e-10 Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 8/164 (4%) Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433 RE+++L L H +++ IF ++ F+ + DL + R ++ + + Q Sbjct: 66 RELKLLKHLRHENIISLSDIFISPFEDIYFVTELLGTDLHRLLTSR-PLETQFIQYFLYQ 124 Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493 + ++++H + HRD+K N+L+ N ++K+ DFG AR + + + + + Sbjct: 125 ILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLAR------IQDPQMTGYVSTRY 178 Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK-HIKQ 536 Y APEI+ D+WS G + M+ F + H+ Q Sbjct: 179 YRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQ 222 >SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 387 Score = 58.8 bits (136), Expect = 2e-09 Identities = 65/252 (25%), Positives = 119/252 (47%), Gaps = 21/252 (8%) Query: 369 KKFLPREIEMLIKLSHPHLVHTHSIFQRR-------YKYFI--FM-RYMERGDLLEFVLQ 418 K+F RE++++ + HP++V + + Y + FM + R L + Q Sbjct: 67 KRFKNRELQIMRIMKHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRL-YTRQ 125 Query: 419 RGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNV-KLSDFGFARMCVD 477 + ++ + +++ QL ++ Y+H I HRDIK +N+LL + KL DFG A++ V Sbjct: 126 KLSMPMLEVKLYIYQLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVA 185 Query: 478 KKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLG-IVVYVMLNRAMPFEDKHIKQ 536 + N ++ S Y APE++ G D+WS G ++ +ML + + I Q Sbjct: 186 GEPN----VSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQ 241 Query: 537 LHQAQINKNWKFRSR-YIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLLE 595 L +I K SR I T++ N + P +R+ V + + + S++L+ Sbjct: 242 L--VEIIKILGTPSREQIKTMNPNYMEHRFPQIRPQPLSRV-FSRSVPLDALDLLSKMLQ 298 Query: 596 WTPQETLAYKKA 607 +TP + L +A Sbjct: 299 YTPTDRLTAAEA 310 Score = 56.4 bits (130), Expect = 1e-08 Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 14/160 (8%) Query: 66 KFLPREIDVLVRLNHPHLIHVHSIF----QRKTKYYI-----FMRYTENGDLLSYILKNG 116 +F RE+ ++ + HP+++ + + + + Y+ FM T Y + Sbjct: 68 RFKNRELQIMRIMKHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKL 127 Query: 117 CVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLL-TANFNVKLSDFGFSRFCVESD 175 + + +++ QL L Y+H I HRDIK +N+LL N +KL DFG ++ V Sbjct: 128 SMPMLEVKLYIYQLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVA-- 185 Query: 176 NQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVL 215 +P +S Y S Y APE++ G D+WS G V+ Sbjct: 186 GEPNVS--YICSRYYRAPELIFGATDYTHAIDIWSTGCVM 223 >SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1032 Score = 56.8 bits (131), Expect = 9e-09 Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 4/156 (2%) Query: 324 ILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLS 383 +L+ R + RVYLA+ R++ K L ++ +D+ +K L + M I+ Sbjct: 530 LLKEINRGAYGRVYLAKKRSSGKYFALKMIPKSSLDSLKK----IKGLLLEKRNMHIQRY 585 Query: 384 HPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHE 443 P+ V + F + M Y GD + + G + E + +L AI+ +H+ Sbjct: 586 GPNTVKLYYAFDSGDYLCLVMDYFNGGDCETLIQKLGPLPEQWVCQYAAELLNAIELLHQ 645 Query: 444 LEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKK 479 I H DIK N+L+ +++L+DFG + +KK Sbjct: 646 DGIIHHDIKPANMLVDETGHIRLTDFGLSENVEEKK 681 Score = 55.2 bits (127), Expect = 3e-08 Identities = 40/149 (26%), Positives = 70/149 (46%), Gaps = 5/149 (3%) Query: 21 LTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVK-FLPREIDVLVRLN 79 L K + GAY +VYL +K+ S A K+I + +K L + ++ ++ Sbjct: 530 LLKEINRGAYGRVYL----AKKRSSGKYFALKMIPKSSLDSLKKIKGLLLEKRNMHIQRY 585 Query: 80 HPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHE 139 P+ + ++ F + M Y GD + I K G + E + +L ++ LH+ Sbjct: 586 GPNTVKLYYAFDSGDYLCLVMDYFNGGDCETLIQKLGPLPEQWVCQYAAELLNAIELLHQ 645 Query: 140 LEIAHRDIKCENVLLTANFNVKLSDFGFS 168 I H DIK N+L+ +++L+DFG S Sbjct: 646 DGIIHHDIKPANMLVDETGHIRLTDFGLS 674 Score = 49.2 bits (112), Expect = 2e-06 Identities = 25/95 (26%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Query: 173 ESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRK 232 + +N+ + + G+ +Y APEIL G + D+W++G V+F ML + PF+ ++ Sbjct: 766 KKENRTFIKKDISGTPNYMAPEILMGVD--TQMGDIWAMGCVIFEMLTGTRPFEANTVKA 823 Query: 233 LYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPD 267 ++ + + RV S E ++ L++PD Sbjct: 824 IWARIERNDIGWTKRVKESCSKEAVDLITKLMDPD 858 Score = 45.6 bits (103), Expect = 2e-05 Identities = 31/103 (30%), Positives = 53/103 (51%), Gaps = 5/103 (4%) Query: 476 VDKKLNE-IRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHI 534 ++KK N + G+ +Y APEIL G + D+W++G V++ ML PFE + Sbjct: 764 LEKKENRTFIKKDISGTPNYMAPEILMGVD--TQMGDIWAMGCVIFEMLTGTRPFEANTV 821 Query: 535 KQLHQAQINKN-WKFRSRYIDTISDNCKRLIGLMLEPNHQNRL 576 K + A+I +N + R ++ S LI +++P+ RL Sbjct: 822 KAI-WARIERNDIGWTKRVKESCSKEAVDLITKLMDPDCNKRL 863 >SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1087 Score = 56.0 bits (129), Expect = 2e-08 Identities = 38/94 (40%), Positives = 50/94 (53%), Gaps = 9/94 (9%) Query: 127 TRQLALGLQYLHELEIAHRDIKCENVLLTANF--NVKLSDFGFSRFCVESDNQPVLSETY 184 TRQL L L+E + H D+K EN+LL F VK+ DFG S C E + TY Sbjct: 806 TRQLIQCLTLLNEKHVIHCDLKPENILLCHPFKSQVKVIDFGSS--CFEGE----CVYTY 859 Query: 185 CGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVM 218 S Y +PE++ G Y P D+WSLG ++ M Sbjct: 860 IQSRFYRSPEVILGMGY-GTPIDVWSLGCIIAEM 892 Score = 50.0 bits (114), Expect = 1e-06 Identities = 33/94 (35%), Positives = 49/94 (52%), Gaps = 9/94 (9%) Query: 431 TRQLALAIQYMHELEIAHRDIKCENVLL--TANQNVKLSDFGFARMCVDKKLNEIRSETF 488 TRQL + ++E + H D+K EN+LL VK+ DFG + C + + T+ Sbjct: 806 TRQLIQCLTLLNEKHVIHCDLKPENILLCHPFKSQVKVIDFGSS--CFEGEC----VYTY 859 Query: 489 CGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVM 522 S Y +PE++ G Y P DVWSLG ++ M Sbjct: 860 IQSRFYRSPEVILGMGY-GTPIDVWSLGCIIAEM 892 >SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1072 Score = 51.2 bits (117), Expect = 4e-07 Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 12/82 (14%) Query: 433 QLALAIQYMHELEIAHRDIKCENVLLTANQNVKL---------SDFGFARMCVDKKLNEI 483 Q+A + ++H L++ HRD+K +N+LL N + L SDFG ++ +D + + Sbjct: 757 QIAFGVSHLHSLDLVHRDLKPQNILLVVNNSPNLSKTRVRALISDFGLSKK-LDFNQSSL 815 Query: 484 RSETF--CGSLSYTAPEILQGT 503 R+ TF GS + +PEIL G+ Sbjct: 816 RNTTFEAAGSYGWRSPEILSGS 837 Score = 46.8 bits (106), Expect = 9e-06 Identities = 28/81 (34%), Positives = 46/81 (56%), Gaps = 12/81 (14%) Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKL---------SDFGFSRFCVESDNQPV 179 Q+A G+ +LH L++ HRD+K +N+LL N + L SDFG S+ ++ + + Sbjct: 757 QIAFGVSHLHSLDLVHRDLKPQNILLVVNNSPNLSKTRVRALISDFGLSK-KLDFNQSSL 815 Query: 180 LSETY--CGSMSYAAPEILRG 198 + T+ GS + +PEIL G Sbjct: 816 RNTTFEAAGSYGWRSPEILSG 836 >SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein kinase Ppk5 |Schizosaccharomyces pombe|chr 1|||Manual Length = 836 Score = 48.4 bits (110), Expect = 3e-06 Identities = 38/88 (43%), Positives = 47/88 (53%), Gaps = 12/88 (13%) Query: 133 GLQYLHELE---IAHRDIKCENVLLT--ANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187 GLQ L L+ I H D+K EN+LL+ +KL DFG S F N+ V TY S Sbjct: 628 GLQALRLLQGQNIIHCDLKPENLLLSHPLKARIKLIDFGSSCFY----NEKVY--TYLQS 681 Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVL 215 Y APEI+ G Y K D+WS G +L Sbjct: 682 RFYRAPEIILGLEY-GKEIDIWSFGCIL 708 Score = 44.0 bits (99), Expect = 7e-05 Identities = 57/219 (26%), Positives = 97/219 (44%), Gaps = 34/219 (15%) Query: 437 AIQYMHELEIAHRDIKCENVLLT--ANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSY 494 A++ + I H D+K EN+LL+ +KL DFG + C NE + T+ S Y Sbjct: 631 ALRLLQGQNIIHCDLKPENLLLSHPLKARIKLIDFGSS--CF---YNE-KVYTYLQSRFY 684 Query: 495 TAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF----EDKHIKQLHQA------QINK 544 APEI+ G Y K D+WS G ++ + F E + + + + + + Sbjct: 685 RAPEIILGLEY-GKEIDIWSFGCILAELFTGVPLFPGGNETEQLGYIMEVLGPPPMALIR 743 Query: 545 NWKFRSRYIDT------ISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLLEWTP 598 N Y D+ I+D+ RL L P+ + ++ + + ++ S+ L+W P Sbjct: 744 NSTRSKAYFDSEGKPHPITDSHNRL----LVPSTRTFSQLLNTKQASFLDFLSKCLKWDP 799 Query: 599 QETLAYKKAREEKNKLHKTVETVELPGSSKTEHKVCLPD 637 ++ + A + + L KT + P SK H LPD Sbjct: 800 KDRITVDSALQHEFILGKTSQK---PMVSKGSHP--LPD 833 >SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Schizosaccharomyces pombe|chr 1|||Manual Length = 332 Score = 47.6 bits (108), Expect = 5e-06 Identities = 55/223 (24%), Positives = 96/223 (43%), Gaps = 25/223 (11%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y++ + VG G Y++V+ + S K+++ K K + REI +L L Sbjct: 43 YEIIRKVGRGKYSEVF----EGLNVLNNSKCIIKVLKPVKYKK------IKREIKILQNL 92 Query: 79 -NHPHLIHVHSIF---QRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134 P++I + I + KT IF + +N D + +S+ R ++ +L L Sbjct: 93 AGGPNIISLLDIVRDPESKTPSLIF-EFVDNIDFRTLY---PTLSDYDIRYYSYELLKAL 148 Query: 135 QYLHELEIAHRDIKCENVLLT-ANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAP 193 + H I HRD+K NV++ ++L D+G + F + + S + P Sbjct: 149 DFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFY----HAGMEYNVRVASRYFKGP 204 Query: 194 EILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ 236 E+L D+WS GV+ ++ K F R R Y+Q Sbjct: 205 ELLVDFREYDYSLDIWSFGVMFAALIFKKDTF--FRGRDNYDQ 245 Score = 39.5 bits (88), Expect = 0.001 Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 5/114 (4%) Query: 411 DLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLT-ANQNVKLSDF 469 D ++F + + R ++ +L A+ + H I HRD+K NV++ + ++L D+ Sbjct: 121 DNIDFRTLYPTLSDYDIRYYSYELLKALDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDW 180 Query: 470 GFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVML 523 G A +R S + PE+L D+WS G++ ++ Sbjct: 181 GLAEFYHAGMEYNVR----VASRYFKGPELLVDFREYDYSLDIWSFGVMFAALI 230 >SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizosaccharomyces pombe|chr 2|||Manual Length = 1706 Score = 45.6 bits (103), Expect = 2e-05 Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 11/155 (7%) Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDF-GFSRFCVESDNQP---VLSETY 184 QL G+ H L + H DIK EN+L+T+ LSDF F + DN +T Sbjct: 129 QLLKGISDCHRLGVCHGDIKSENILITSWNWAYLSDFSSFKPTYLPEDNPADYGYFFDTS 188 Query: 185 CGSMSYAAPE-ILRGKPYCPKP----TDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMG 239 + APE + P P D++SLG V +L + P + +L+ + Sbjct: 189 SRRVCNIAPERFVPASQLQPAPLSPAMDIFSLGCVFAELLLEESPL--FTLSQLFSYKAH 246 Query: 240 KKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSA 274 Y +S + I + ++ +L+ DP R SA Sbjct: 247 GSYDLQSVLEQIEDKSTQNMILSMLDRDPSQRLSA 281 Score = 34.3 bits (75), Expect = 0.054 Identities = 17/37 (45%), Positives = 21/37 (56%) Query: 433 QLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDF 469 QL I H L + H DIK EN+L+T+ LSDF Sbjct: 129 QLLKGISDCHRLGVCHGDIKSENILITSWNWAYLSDF 165 >SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 45.6 bits (103), Expect = 2e-05 Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 15/127 (11%) Query: 431 TRQLALAIQYMHELEIAHRDIKCENVLLTAN--QNVKLSDFGFARMCVDK---KLNEIRS 485 ++QL ++ ++H L + H D+K ENVLL +N + ++L +++ ++ +L + S Sbjct: 469 SQQLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGS 528 Query: 486 ETF--------CGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQL 537 TF + Y APEI+ G + P DVWS+G ++ + F+ H Sbjct: 529 ATFEDEYHSSVVSTRHYRAPEIILGLGW-SYPCDVWSIGCILVELFTGQALFQ-THEDSE 586 Query: 538 HQAQINK 544 H + K Sbjct: 587 HLCMMEK 593 Score = 42.7 bits (96), Expect = 2e-04 Identities = 54/224 (24%), Positives = 90/224 (40%), Gaps = 29/224 (12%) Query: 12 NTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPRE 71 N+ Y + + +G G + KV + Y H C I T PK + E Sbjct: 355 NSKFANRYTVVRLLGHGTFGKV-IQCYDQSTGRH-----CAIKVTRAIPKYREASLI--E 406 Query: 72 IDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSY----ILKNGCVSE---NQAR 124 + VL + H + + Q + + DL + LKN + Sbjct: 407 LRVLQTIAHSDPTNENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKNNNYIPFPLKHIQ 466 Query: 125 VWTRQLALGLQYLHELEIAHRDIKCENVLLTANFN--VKLSDFGFSRFCVES-------D 175 + ++QL + +LH L + H D+K ENVLL +N + ++L +S+ + S Sbjct: 467 MLSQQLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDF 526 Query: 176 NQPVLSETYCGSM----SYAAPEILRGKPYCPKPTDLWSLGVVL 215 + Y S+ Y APEI+ G + P D+WS+G +L Sbjct: 527 GSATFEDEYHSSVVSTRHYRAPEIILGLGW-SYPCDVWSIGCIL 569 >SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 306 Score = 45.2 bits (102), Expect = 3e-05 Identities = 38/157 (24%), Positives = 73/157 (46%), Gaps = 7/157 (4%) Query: 74 VLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALG 133 +L + HPH+ + F +++ + +LS ++ + + + ++ Q++ Sbjct: 59 ILESIGHPHIERIVDSFIDNEAGSVYLITSFKSFVLSDVMDEISI-DTKCKI-VLQISSA 116 Query: 134 LQYLHELEIAHRDIKCENVLL-TANFNVKLSDF--GFSRFCVESDNQPVLSETYCGSMSY 190 L+YL + I HRDI N+LL + N LSDF +S+ + Q ++ + G+ Y Sbjct: 117 LEYLEKHGILHRDIHPNNILLDSMNGPAYLSDFSIAWSKQHPGEEVQELIPQ--IGTGHY 174 Query: 191 AAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDD 227 A E L G D W+ G+++ + + FDD Sbjct: 175 RAIETLFGCHSYGHEVDRWTFGILIAELFSNQALFDD 211 Score = 44.8 bits (101), Expect = 4e-05 Identities = 46/199 (23%), Positives = 91/199 (45%), Gaps = 15/199 (7%) Query: 336 VYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQ 395 V++ E +N+ K L ++ + + P D ++ L +L + HPH+ F Sbjct: 25 VFVGERKNSKK---LYVIKVQGLVFKRPPHDAMRGKL-----ILESIGHPHIERIVDSFI 76 Query: 396 RRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCEN 455 +++ + +L V+ ++ + + +I Q++ A++Y+ + I HRDI N Sbjct: 77 DNEAGSVYLITSFKSFVLSDVMDEISI-DTKCKI-VLQISSALEYLEKHGILHRDIHPNN 134 Query: 456 VLL-TANQNVKLSDFGFA--RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDV 512 +LL + N LSDF A + +++ E+ + G+ Y A E L G D Sbjct: 135 ILLDSMNGPAYLSDFSIAWSKQHPGEEVQELIPQ--IGTGHYRAIETLFGCHSYGHEVDR 192 Query: 513 WSLGIVVYVMLNRAMPFED 531 W+ GI++ + + F+D Sbjct: 193 WTFGILIAELFSNQALFDD 211 >SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 665 Score = 43.2 bits (97), Expect = 1e-04 Identities = 27/108 (25%), Positives = 49/108 (45%) Query: 66 KFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARV 125 + L E+ L L+H +LI + F + Y + LS ++ SE Sbjct: 428 RLLLEELQRLSGLSHKNLIRYNESFWYLNNIWSVFEYKDPSTKLSALIPKYFFSELNIAS 487 Query: 126 WTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVE 173 +++ GL +LH IAH ++ E + LT + +K+ ++ FS +E Sbjct: 488 ICYEISSGLAFLHNSGIAHHNLTTECIYLTKSSCLKIGNYAFSSPYIE 535 Score = 41.5 bits (93), Expect = 4e-04 Identities = 32/169 (18%), Positives = 73/169 (43%), Gaps = 7/169 (4%) Query: 369 KKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQAR 428 ++ L E++ L LSH +L+ + F + Y + L ++ + E Sbjct: 427 RRLLLEELQRLSGLSHKNLIRYNESFWYLNNIWSVFEYKDPSTKLSALIPKYFFSELNIA 486 Query: 429 IWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETF 488 +++ + ++H IAH ++ E + LT + +K+ ++ F+ ++++ N Sbjct: 487 SICYEISSGLAFLHNSGIAHHNLTTECIYLTKSSCLKIGNYAFSSPYIERQTNR------ 540 Query: 489 CGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQL 537 G++S+ +++ DV SLG+V + F K I+ + Sbjct: 541 -GAVSHVPDWLIEKNYKEGFMKDVKSLGLVALEIFQGQPNFFRKSIQSI 588 >SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizosaccharomyces pombe|chr 1|||Manual Length = 534 Score = 42.3 bits (95), Expect = 2e-04 Identities = 36/95 (37%), Positives = 49/95 (51%), Gaps = 11/95 (11%) Query: 124 RVWTRQLALGLQYLHELEIAHRDIKCENVLL--TANFNVKLSDFGFSRFCVESDNQPVLS 181 R + QL L + I H D+K EN+LL ++ VK+ DFG + C E Q V Sbjct: 235 RSFATQLLSCTSLLKQARIIHCDLKPENILLQDLSSPIVKVIDFGSA--CHE--RQTVY- 289 Query: 182 ETYCGSMSYAAPEILRGKPY-CPKPTDLWSLGVVL 215 TY S Y +PE++ G Y C D+WSLG +L Sbjct: 290 -TYIQSRFYRSPEVILGLHYNC--GIDMWSLGCIL 321 Score = 40.3 bits (90), Expect = 8e-04 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 9/94 (9%) Query: 428 RIWTRQLALAIQYMHELEIAHRDIKCENVLL--TANQNVKLSDFGFARMCVDKKLNEIRS 485 R + QL + + I H D+K EN+LL ++ VK+ DFG A C +++ Sbjct: 235 RSFATQLLSCTSLLKQARIIHCDLKPENILLQDLSSPIVKVIDFGSA--CHERQ----TV 288 Query: 486 ETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVV 519 T+ S Y +PE++ G Y D+WSLG ++ Sbjct: 289 YTYIQSRFYRSPEVILGLHY-NCGIDMWSLGCIL 321 >SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizosaccharomyces pombe|chr 1|||Manual Length = 344 Score = 40.7 bits (91), Expect = 6e-04 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 15/130 (11%) Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78 Y++ K +GEG +A VYL + S E + A K I+ + K +K +E D + Sbjct: 32 YRIQKLLGEGGFAFVYLVQNVSNEKLY----ALKKIKCSFGNKG--IKKAMKEADYHRKF 85 Query: 79 NHPHLI--HVHSIFQR---KTKYYIFMRYTENGDLLSYI----LKNGCVSENQARVWTRQ 129 +L+ + H + + YI Y G + I ++ +SE + VW Sbjct: 86 KSNYLLKSYTHQLVKEADGSEFVYILFPYFAKGSVAQVIRNCDIEGSYISEKRILVWCSC 145 Query: 130 LALGLQYLHE 139 L LQYLHE Sbjct: 146 LCKALQYLHE 155 Score = 38.7 bits (86), Expect = 0.003 Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 11/93 (11%) Query: 448 HRDIKCENVLLTAN-QNVKLSDFG-------FARMCVDKKLNEIRSETFCGSLSYTAPEI 499 H DIK +N+LL N + + L+DFG FA + + ++ C ++ + APE+ Sbjct: 192 HGDIKPDNLLLHENSREIVLTDFGSICLVPIFASNNSEAIAIQDKASENC-TMPFRAPEL 250 Query: 500 --LQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530 ++ + + D+WS G +Y ++ A PFE Sbjct: 251 FHVKAGSTITEKADIWSFGCTLYTIMFHASPFE 283 Score = 36.3 bits (80), Expect = 0.013 Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 17/148 (11%) Query: 144 HRDIKCENVLLTANFN-VKLSDFGFSRFCV----ESDNQPVLSETYCGS----MSYAAPE 194 H DIK +N+LL N + L+DFG C+ S+N ++ S M + APE Sbjct: 192 HGDIKPDNLLLHENSREIVLTDFG--SICLVPIFASNNSEAIAIQDKASENCTMPFRAPE 249 Query: 195 ILRGKP--YCPKPTDLWSLGVVLFVMLNKSMPFDD--TRMRKLYEQQMGKKYRFRSRVAS 250 + K + D+WS G L+ ++ + PF+ ++ L +Y F R Sbjct: 250 LFHVKAGSTITEKADIWSFGCTLYTIMFHASPFEREVSQGGSLALAVCNAQYSF-PRKHP 308 Query: 251 ILSLECKTVVKHLLEPDPGLRHSATNVL 278 +L C+ +V+ L+ +P R SA +L Sbjct: 309 YSTLLCE-IVEACLQREPNKRPSARELL 335 Score = 28.3 bits (60), Expect = 3.6 Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 14/116 (12%) Query: 336 VYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQ 395 VYL + N S N+KL A K I S + K + K ++ +TH + + Sbjct: 46 VYLVQ--NVS-NEKL--YALKKIKCSFGNKGIKKAMKEADYHRKFKSNYLLKSYTHQLVK 100 Query: 396 R----RYKYFIFMRYMERGDLLEFV----LQRGAVQEDQARIWTRQLALAIQYMHE 443 + Y +F Y +G + + + ++ + E + +W L A+QY+HE Sbjct: 101 EADGSEFVYILFP-YFAKGSVAQVIRNCDIEGSYISEKRILVWCSCLCKALQYLHE 155 >SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 400 Score = 38.7 bits (86), Expect = 0.003 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 6/103 (5%) Query: 433 QLALAIQYMHELEIAHRDIKCENVLLTANQN-VKLSDFGFARMCVDKKLN---EIR-SET 487 QL I+Y+H HRDIK +N L+ + N V + DFG A+ D K + R ++ Sbjct: 114 QLISRIEYVHSKSFLHRDIKPDNFLMKKHSNVVTMIDFGLAKKYRDFKTHVHIPYRDNKN 173 Query: 488 FCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530 G+ Y + G + D+ SLG V+ ++P++ Sbjct: 174 LTGTARYASINTHIGIEQ-SRRDDLESLGYVLLYFCRGSLPWQ 215 Score = 35.9 bits (79), Expect = 0.018 Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 6/102 (5%) Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFN-VKLSDFGFSRFCVESDNQPVL----SET 183 QL ++Y+H HRDIK +N L+ + N V + DFG ++ + + ++ Sbjct: 114 QLISRIEYVHSKSFLHRDIKPDNFLMKKHSNVVTMIDFGLAKKYRDFKTHVHIPYRDNKN 173 Query: 184 YCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 G+ YA+ G + DL SLG VL S+P+ Sbjct: 174 LTGTARYASINTHIGIEQ-SRRDDLESLGYVLLYFCRGSLPW 214 >SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizosaccharomyces pombe|chr 2|||Manual Length = 435 Score = 37.5 bits (83), Expect = 0.006 Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 10/128 (7%) Query: 411 DLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLL----TANQN-VK 465 DL E+ +R +V+ + +Q+ +Q +HE + +RDIK +N L+ + N N V Sbjct: 94 DLFEWCGRRFSVKT--VAMTAKQMLSRVQTIHEKNLVYRDIKPDNFLIGRPSSRNANMVY 151 Query: 466 LSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPY---LPKPTDVWSLGIVVYVM 522 + DFG A+ D K + + SLS TA + T + D+ SLG V Sbjct: 152 MVDFGMAKYYRDPKTKQHIPYSERKSLSGTARYMSINTHLGREQSRRDDLESLGHVFMYF 211 Query: 523 LNRAMPFE 530 L ++P++ Sbjct: 212 LRGSLPWQ 219 Score = 33.1 bits (72), Expect = 0.13 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 10/107 (9%) Query: 128 RQLALGLQYLHELEIAHRDIKCENVLL----TANFN-VKLSDFGFSRFCVESDNQPVL-- 180 +Q+ +Q +HE + +RDIK +N L+ + N N V + DFG +++ + + + Sbjct: 113 KQMLSRVQTIHEKNLVYRDIKPDNFLIGRPSSRNANMVYMVDFGMAKYYRDPKTKQHIPY 172 Query: 181 --SETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 ++ G+ Y + G+ + DL SLG V L S+P+ Sbjct: 173 SERKSLSGTARYMSINTHLGREQ-SRRDDLESLGHVFMYFLRGSLPW 218 >SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 507 Score = 36.7 bits (81), Expect = 0.010 Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 2/59 (3%) Query: 172 VESDNQPVLSETYCGSMSYAAPEIL-RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTR 229 +++D +P G+ + APE+L + PK D+WS GV+L L K P +++ Sbjct: 276 IKNDTRPSKRANRAGTRGFRAPEVLFKCSSQSPK-VDIWSAGVILLSFLTKRFPMFNSK 333 Score = 29.5 bits (63), Expect = 1.5 Identities = 42/179 (23%), Positives = 71/179 (39%), Gaps = 28/179 (15%) Query: 15 LTKGYKLTKFVGEGAYAKVYLTE------YSSKEDSHKSTLA--------CKIIETAKAP 60 L + Y+L + +GEG ++ VY E Y + D L + E ++ P Sbjct: 64 LQENYRLIEKIGEGTFSSVYKAEDLHYGRYINDWDIQSEVLKESSFGKEKIPVNEDSRKP 123 Query: 61 KDFVVKFL-----P----REIDVLVRLNHPHLIH-VHSIFQRKTKYYIFMRYTENGDLLS 110 K +K + P E+++L L +I + + + + + + + Y E+ D Sbjct: 124 KYVAIKKIYATSSPARIYNELEILYLLRGSSVIAPLITALRNEDQVLVVLPYYEHTDFRQ 183 Query: 111 YILKNGCVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANF-NVKLSDFGFS 168 Y S ++ R L +Q L I HRDIK N L + L DFG + Sbjct: 184 YY---STFSYRDMSIYFRCLFQAMQQTQTLGIIHRDIKPSNFLFDVRTKHGVLVDFGLA 239 Score = 29.1 bits (62), Expect = 2.0 Identities = 40/166 (24%), Positives = 63/166 (37%), Gaps = 12/166 (7%) Query: 309 KLSDVHKHPPKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFV 368 K D+H DI +ES+F S+ K + K+ TS+ R + Sbjct: 84 KAEDLHYGRYINDWDIQSEVLKESSFGKEKIPVNEDSRKPKYVAIK-KIYATSSPARIY- 141 Query: 369 KKFLPREIEMLIKLSHPHLVHTH-SIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQA 427 E+E+L L ++ + + + + + Y E D ++ Sbjct: 142 -----NELEILYLLRGSSVIAPLITALRNEDQVLVVLPYYEHTDFRQYY---STFSYRDM 193 Query: 428 RIWTRQLALAIQYMHELEIAHRDIKCENVLL-TANQNVKLSDFGFA 472 I+ R L A+Q L I HRDIK N L ++ L DFG A Sbjct: 194 SIYFRCLFQAMQQTQTLGIIHRDIKPSNFLFDVRTKHGVLVDFGLA 239 Score = 28.7 bits (61), Expect = 2.7 Identities = 11/39 (28%), Positives = 19/39 (48%) Query: 490 GSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMP 528 G+ + APE+L D+WS G+++ L + P Sbjct: 290 GTRGFRAPEVLFKCSSQSPKVDIWSAGVILLSFLTKRFP 328 >SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosaccharomyces pombe|chr 1|||Manual Length = 439 Score = 35.1 bits (77), Expect = 0.031 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 8/107 (7%) Query: 432 RQLALAIQYMHELEIAHRDIKCENVLL----TANQNVKLS-DFGFARMCVDKKLNEIRSE 486 +Q+ IQ +HE +RDIK +N L+ + +NV + DFG A+ D K + R Sbjct: 116 KQMITRIQSVHERHFIYRDIKPDNFLIGFPGSKTENVIYAVDFGMAKQYRDPKTHVHRPY 175 Query: 487 TFCGSLSYTAPEILQGTPY---LPKPTDVWSLGIVVYVMLNRAMPFE 530 SLS TA + T + D+ S+G V L ++P++ Sbjct: 176 NEHKSLSGTARYMSINTHLGREQSRRDDLESMGHVFMYFLRGSLPWQ 222 >SPAC27E2.09 |mak2|phk1|histidine kinase Mak2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 2310 Score = 35.1 bits (77), Expect = 0.031 Identities = 44/197 (22%), Positives = 85/197 (43%), Gaps = 19/197 (9%) Query: 440 YMHELEIAHRDIKCENVL--LTANQNVKLSDFGFARMCVDKKLNEI------RSETFCGS 491 ++HE +I H +I+ + L A + KL G + + L+ + + + C Sbjct: 137 FLHEKKIVHGEIRLDTFHYDLNAPIHAKLLTIGSSVSPIRFTLSSLNWKRLYQVQNICHK 196 Query: 492 LSYTAPEILQ--GTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKH---IKQLHQAQINKNW 546 L + +PE + G P L +D++SLGI+ YV+L + P+ + ++ +H Q Sbjct: 197 LQFFSPEQIGNVGRP-LDSRSDIYSLGILFYVILTKQYPWGGQSMRIVQSIHMRQFPSVL 255 Query: 547 KFRSRYIDTISDNCKRLIGLMLEPNHQNRLKI-YDIVN--SEWIAMDSRLLEWTPQETLA 603 R + +++ + + + Y IV E+ + S L Q+ L+ Sbjct: 256 PRRPDAFPALDQLIQKMTAKSMNSRISSATDLCYTIVELMQEFSTITSSPL--LDQKLLS 313 Query: 604 YKKAREEKNKLHKTVET 620 K ++EK K K + T Sbjct: 314 INKPQQEKLKFPKLLLT 330 >SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosaccharomyces pombe|chr 2|||Manual Length = 365 Score = 34.7 bits (76), Expect = 0.041 Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 11/123 (8%) Query: 129 QLALGLQYLHELEIAHRDIKCENVLL---TANFNVKLSDFGFSRFCVESDNQPVL----S 181 QL ++++H HRDIK +N L+ V + DFG ++ + + + Sbjct: 113 QLISRIEFIHSKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKYRDHKTHLHIPYREN 172 Query: 182 ETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDD---TRMRKLYEQQM 238 + G+ YA+ G + DL SLG VL S+P+ T ++ YE+ M Sbjct: 173 KNLTGTARYASINTHLGIEQ-SRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQKYEKIM 231 Query: 239 GKK 241 KK Sbjct: 232 EKK 234 Score = 34.7 bits (76), Expect = 0.041 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 8/105 (7%) Query: 433 QLALAIQYMHELEIAHRDIKCENVLL---TANQNVKLSDFGFARMCVDKK----LNEIRS 485 QL I+++H HRDIK +N L+ V + DFG A+ D K + + Sbjct: 113 QLISRIEFIHSKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKYRDHKTHLHIPYREN 172 Query: 486 ETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530 + G+ Y + G + D+ SLG V+ ++P++ Sbjct: 173 KNLTGTARYASINTHLGIEQ-SRRDDLESLGYVLVYFCRGSLPWQ 216 >SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosaccharomyces pombe|chr 2|||Manual Length = 429 Score = 33.1 bits (72), Expect = 0.13 Identities = 16/51 (31%), Positives = 23/51 (45%) Query: 175 DNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225 D +P G+ + APE+L D+WS+GV+L L PF Sbjct: 252 DPRPTKRADRAGTRGFRAPEVLFRCQNQTSSIDVWSVGVILLCFLTHRYPF 302 Score = 31.5 bits (68), Expect = 0.38 Identities = 13/40 (32%), Positives = 20/40 (50%) Query: 490 GSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF 529 G+ + APE+L DVWS+G+++ L PF Sbjct: 263 GTRGFRAPEVLFRCQNQTSSIDVWSVGVILLCFLTHRYPF 302 >SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 544 Score = 32.3 bits (70), Expect = 0.22 Identities = 15/32 (46%), Positives = 22/32 (68%), Gaps = 1/32 (3%) Query: 433 QLALAIQYMH-ELEIAHRDIKCENVLLTANQN 463 QL +A+ Y+H E I H D+K ENVL+ +Q+ Sbjct: 196 QLLIALDYLHRECGIIHTDLKPENVLICIDQD 227 Score = 30.3 bits (65), Expect = 0.88 Identities = 15/27 (55%), Positives = 18/27 (66%), Gaps = 1/27 (3%) Query: 129 QLALGLQYLH-ELEIAHRDIKCENVLL 154 QL + L YLH E I H D+K ENVL+ Sbjct: 196 QLLIALDYLHRECGIIHTDLKPENVLI 222 >SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizosaccharomyces pombe|chr 2|||Manual Length = 446 Score = 31.9 bits (69), Expect = 0.29 Identities = 32/125 (25%), Positives = 58/125 (46%), Gaps = 12/125 (9%) Query: 128 RQLALGLQYLHELEIAHRDIKCENVLL----TANFN-VKLSDFGFSRFC---VESDNQPV 179 +Q+ +Q +HE + +RDIK +N L+ + N N + + DFG +F V + P Sbjct: 113 KQMLARVQSIHEKSLVYRDIKPDNFLIGRPNSKNANMIYVVDFGMVKFYRDPVTKQHIPY 172 Query: 180 L-SETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTR--MRKLYEQ 236 + G+ Y + G+ + DL +LG V L S+P+ + K + Sbjct: 173 REKKNLSGTARYMSINTHLGREQ-SRRDDLEALGHVFMYFLRGSLPWQGLKAATNKQKYE 231 Query: 237 QMGKK 241 ++G+K Sbjct: 232 RIGEK 236 Score = 29.5 bits (63), Expect = 1.5 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Query: 432 RQLALAIQYMHELEIAHRDIKCENVLL----TANQN-VKLSDFG---FARMCVDKKLNEI 483 +Q+ +Q +HE + +RDIK +N L+ + N N + + DFG F R V K+ Sbjct: 113 KQMLARVQSIHEKSLVYRDIKPDNFLIGRPNSKNANMIYVVDFGMVKFYRDPVTKQHIPY 172 Query: 484 R-SETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530 R + G+ Y + G + D+ +LG V L ++P++ Sbjct: 173 REKKNLSGTARYMSINTHLGREQ-SRRDDLEALGHVFMYFLRGSLPWQ 219 >SPCC74.06 |mak3|phk2|histidine kinase Mak3 |Schizosaccharomyces pombe|chr 3|||Manual Length = 2344 Score = 31.1 bits (67), Expect = 0.50 Identities = 27/109 (24%), Positives = 55/109 (50%), Gaps = 10/109 (9%) Query: 134 LQYLHELEIAHRDIKCENVLLTANF-NVKLSDFG----FSRFCVESDNQPVLSETYCGSM 188 ++YLH + H +I+ ++ + +++ NV + G + C+++ N SE SM Sbjct: 136 IEYLHSKGMVHGEIRLDSFIPISSYDNVYMLTVGSGASYFHNCLQAHNWRKYSED-SESM 194 Query: 189 S---YAAPEILRGKPYCPK-PTDLWSLGVVLFVMLNKSMPFDDTRMRKL 233 S + +PE Y TD++SLGV+ F L+ P+ + ++++ Sbjct: 195 SRILFISPEQTGRTSYSVGYRTDIYSLGVLFFHYLSDCSPYTGSFVQRI 243 Score = 29.1 bits (62), Expect = 2.0 Identities = 25/110 (22%), Positives = 56/110 (50%), Gaps = 12/110 (10%) Query: 438 IQYMHELEIAHRDIKCENVL-LTANQNVKLSDFG----FARMCVD----KKLNEIRSETF 488 I+Y+H + H +I+ ++ + +++ NV + G + C+ +K +E SE+ Sbjct: 136 IEYLHSKGMVHGEIRLDSFIPISSYDNVYMLTVGSGASYFHNCLQAHNWRKYSE-DSESM 194 Query: 489 CGSLSYTAPEILQGTPY-LPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQL 537 L + +PE T Y + TD++SLG++ + L+ P+ ++++ Sbjct: 195 SRIL-FISPEQTGRTSYSVGYRTDIYSLGVLFFHYLSDCSPYTGSFVQRI 243 >SPAC20H4.05c |||adducin|Schizosaccharomyces pombe|chr 1|||Manual Length = 221 Score = 30.7 bits (66), Expect = 0.67 Identities = 17/52 (32%), Positives = 25/52 (48%) Query: 590 DSRLLEWTPQETLAYKKAREEKNKLHKTVETVELPGSSKTEHKVCLPDSLVE 641 DS T E L+Y + N HK + +++P + T H+ L DSL E Sbjct: 118 DSDHFSATGFEVLSYIPKGSKNNGFHKPTDKIKIPFINNTAHESDLHDSLQE 169 >SPCC736.10c |mrps8||mitochondrial ribosomal protein subunit S8|Schizosaccharomyces pombe|chr 3|||Manual Length = 152 Score = 30.3 bits (65), Expect = 0.88 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%) Query: 587 IAMDSRLLEWTPQETLAYKKAREEKNKLHKTVETVELPGSSKTEHKVCLPDSLVENNLDG 646 ++ SR + TP E L + K R K +E E+ G +T+H + D ++NNL G Sbjct: 89 VSKPSRKVNLTPSELLQFAKGR--KVSFVNGLEPAEV-GIVETKHGIMSIDDAIKNNLGG 145 >SPBC29A3.14c |trt1||telomerase reverse transcriptase 1 protein Trt1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 988 Score = 29.9 bits (64), Expect = 1.2 Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 2/66 (3%) Query: 506 LPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIG 565 L K + S VV L + P ++ K+LH+ ++K + YIDT D ++++ Sbjct: 278 LHKVIPLVSQSTVVPKRLLKVYPLIEQTAKRLHRISLSKVYNHYCPYIDTHDD--EKILS 335 Query: 566 LMLEPN 571 L+PN Sbjct: 336 YSLKPN 341 >SPBC336.14c |ppk26||serine/threonine protein kinase Ppk26|Schizosaccharomyces pombe|chr 2|||Manual Length = 589 Score = 29.5 bits (63), Expect = 1.5 Identities = 31/126 (24%), Positives = 52/126 (41%), Gaps = 17/126 (13%) Query: 72 IDVLVRLNHPHLIHVHSIFQRKTKY-------YIFMRYTEN-GDLLSYILKNGCVSENQA 123 +D L + HP+++ HS F T + Y F T G+L KN E Sbjct: 269 VDKLKNVFHPNIVPFHSAFHTDTFHDSSLLLIYDFYPCTTTLGELYLNNSKNSVKLEENR 328 Query: 124 RVWTR-------QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDN 176 ++ R QL + L YLH+ A + +L+ +++S G + + + N Sbjct: 329 KIPERELWNYFFQLTIALSYLHKSGFACNKLTPSRILVDQTERIRIS--GCADYELVVSN 386 Query: 177 QPVLSE 182 +P L E Sbjct: 387 KPPLEE 392 >SPCC24B10.22 ||SPCPB16A4.01|mitochondrial DNA polymerase gamma catalytic subunit|Schizosaccharomyces pombe|chr 3|||Manual Length = 1018 Score = 29.5 bits (63), Expect = 1.5 Identities = 20/73 (27%), Positives = 38/73 (52%), Gaps = 7/73 (9%) Query: 542 INKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDS---RLLEWTP 598 +N +W +RYI+ + + +++I L+ + Q K D++N++ + R L+WTP Sbjct: 393 VNHSW---TRYINGVEEQYQQMIQLVDQKLSQYAEKAKDLINTKDTVLKDPWLRQLDWTP 449 Query: 599 QETL-AYKKAREE 610 KKA +E Sbjct: 450 CNLYRKLKKATQE 462 >SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces pombe|chr 1|||Manual Length = 704 Score = 29.5 bits (63), Expect = 1.5 Identities = 25/114 (21%), Positives = 50/114 (43%), Gaps = 11/114 (9%) Query: 465 KLSDFGFARMCVD---KKLNEIRSETFCGSLSYTAPEI----LQGTPYLPKPTDVWSLGI 517 K+ DFG D + N +F G+ +Y APE+ ++ TD+++LGI Sbjct: 540 KIGDFGLVLSQSDNLEEGTNSSAESSFVGTSTYAAPELFSKHMRSVMNNNSSTDIYALGI 599 Query: 518 VVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPN 571 + + +L PF + + A + K F ++D++ + + ++ N Sbjct: 600 LFFELL---YPFNTRMERASAIANLKKG-IFPHDFLDSMPEEASLIRSMLSSSN 649 Score = 27.5 bits (58), Expect = 6.2 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 7/60 (11%) Query: 133 GLQYLHE-LEIAHRDIKCENVLLTANFNVKLSDFGFSRFC----VESDN--QPVLSETYC 185 G+ YLH+ + + HRD+K N+ L++ + + F VE N +PV T C Sbjct: 477 GVLYLHDAMHLVHRDLKPRNIFLSSGVHSEPCSVCLPNFSDEDNVEVSNAYEPVNQRTLC 536 >SPAC144.05 |||ATP-dependent DNA helicase|Schizosaccharomyces pombe|chr 1|||Manual Length = 1375 Score = 29.1 bits (62), Expect = 2.0 Identities = 17/63 (26%), Positives = 33/63 (52%), Gaps = 3/63 (4%) Query: 38 YSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPH---LIHVHSIFQRKT 94 Y +D + ++ II+T+K ++F KF+P+++ + RL + LI H I + Sbjct: 719 YLLAQDLRRKIMSDVIIKTSKHLEEFSEKFIPKKLVKIPRLQKSYAKGLITGHGIIEDYN 778 Query: 95 KYY 97 + Y Sbjct: 779 RLY 781 >SPBC19G7.13 |trf1||telomeric DNA binding factor Trf1|Schizosaccharomyces pombe|chr 2|||Manual Length = 485 Score = 28.7 bits (61), Expect = 2.7 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Query: 321 QGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPRE 375 +GDIL +L RNA +DKL+ + ++I+ TA ++ + F P+E Sbjct: 239 KGDILNDLFPSDMAHRFLIR-RNAKLDDKLTYVEKQIIEKCTARKERLANFSPQE 292 >SPBC691.03c |apl3||AP-2 adaptor complex subunit Alp3 |Schizosaccharomyces pombe|chr 2|||Manual Length = 878 Score = 28.3 bits (60), Expect = 3.6 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 3/61 (4%) Query: 6 TTPSEENTLLTKGYKLTKFVGE--GAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDF 63 ++PS LLT KL E AKV+ EYS+ + AC+ ++ K P+DF Sbjct: 522 SSPSTRVLLLTTLIKLANLQPELNDRIAKVF-QEYSTIINPEVQQRACEYLQLLKMPRDF 580 Query: 64 V 64 + Sbjct: 581 L 581 >SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces pombe|chr 1|||Manual Length = 639 Score = 28.3 bits (60), Expect = 3.6 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 11/76 (14%) Query: 172 VESDNQPVLSET--YCGSMSYAAPEILRGKPY----CPKPTDLWSLGVVLFVMLNKSMPF 225 +E ++ P L + + G+ +YAAPE+L K D +SLG+VLF +L+ PF Sbjct: 475 LERNHLPNLQDETQHIGTATYAAPELLDAMSSQHNKFTKKIDTFSLGMVLFELLH---PF 531 Query: 226 DDT--RMRKLYEQQMG 239 R KL + + G Sbjct: 532 QTNMERATKLQDLRRG 547 >SPAC22A12.03c |csn4||COP9/signalosome complex subunit Csn4 |Schizosaccharomyces pombe|chr 1|||Manual Length = 377 Score = 27.9 bits (59), Expect = 4.7 Identities = 17/70 (24%), Positives = 32/70 (45%) Query: 435 ALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSY 494 ALA+ Y +E E+ + +C N+ +N K +D F+ + V ++ + S Y Sbjct: 21 ALALHYTNEKELFEQAKRCLNICCGSNNFAKRNDVLFSLLDVAVSISSLELRKELISELY 80 Query: 495 TAPEILQGTP 504 + L+ P Sbjct: 81 VPVQSLEEAP 90 >SPBC428.08c |clr4||histone H3 methyltransferase Clr4|Schizosaccharomyces pombe|chr 2|||Manual Length = 490 Score = 27.5 bits (58), Expect = 6.2 Identities = 17/64 (26%), Positives = 26/64 (40%) Query: 32 KVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQ 91 K+ T KE+S K L I+ A +PK + PR L H +F+ Sbjct: 151 KLGKTRNEVKEESQKRELVSNSIKEATSPKTSSILTKPRNPSKLDSYTHLSFYEKRELFR 210 Query: 92 RKTK 95 +K + Sbjct: 211 KKLR 214 >SPAC7D4.04 |taf1||Taz1 interacting factor 1|Schizosaccharomyces pombe|chr 1|||Manual Length = 926 Score = 27.5 bits (58), Expect = 6.2 Identities = 17/62 (27%), Positives = 28/62 (45%) Query: 266 PDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKEDRRKLSDVHKHPPKRQGDIL 325 P L + +L + W +DS L +++A A A KR ++ + + P K I Sbjct: 188 PTGSLPITPLKILSTNWTKLDSWLNSISARYAEAQKRVQQCIGAANSIIVSPFKEVPSIK 247 Query: 326 EG 327 EG Sbjct: 248 EG 249 >SPAP27G11.07c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 238 Score = 27.5 bits (58), Expect = 6.2 Identities = 16/69 (23%), Positives = 32/69 (46%), Gaps = 2/69 (2%) Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVK--LSDFGFARMCVDKKLNEIRSETFC 489 +++ + MH+ +I H D+ N++L ++ N DFG + ++ + Sbjct: 130 KRIGSEVAKMHKNDIVHGDLTTSNMMLESHNNPVPIFIDFGLGSVSESEEDKAVDIYVLE 189 Query: 490 GSLSYTAPE 498 +LS T PE Sbjct: 190 RALSSTLPE 198 >SPAC22F3.12c |rgs1||regulator of G-protein signaling Rgs1|Schizosaccharomyces pombe|chr 1|||Manual Length = 481 Score = 27.1 bits (57), Expect = 8.2 Identities = 9/29 (31%), Positives = 20/29 (68%) Query: 575 RLKIYDIVNSEWIAMDSRLLEWTPQETLA 603 + +++ I +EW+ ++ LL+W+ ET+A Sbjct: 250 KYQMFGIDIAEWLMCNTMLLDWSEMETVA 278 >SPAC3A11.12c |rpt5|pam2, tbp1|19S proteasome regulatory subunit Rpt5|Schizosaccharomyces pombe|chr 1|||Manual Length = 438 Score = 27.1 bits (57), Expect = 8.2 Identities = 15/55 (27%), Positives = 32/55 (58%), Gaps = 1/55 (1%) Query: 272 HSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKEDRRKLSDVHKHPPKRQGDILE 326 +S T +L+++ M S L ++ L++ KE++ K+S+ +K P G+++E Sbjct: 40 NSRTRLLENDIKVMKSEFQRLTHEKSTMLEKIKENQEKISN-NKMLPYLVGNVVE 93 Database: spombe Posted date: Oct 3, 2007 3:31 PM Number of letters in database: 2,362,478 Number of sequences in database: 5004 Lambda K H 0.320 0.135 0.400 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 3,105,752 Number of Sequences: 5004 Number of extensions: 135112 Number of successful extensions: 880 Number of sequences better than 10.0: 118 Number of HSP's better than 10.0 without gapping: 102 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 318 Number of HSP's gapped (non-prelim): 291 length of query: 655 length of database: 2,362,478 effective HSP length: 77 effective length of query: 578 effective length of database: 1,977,170 effective search space: 1142804260 effective search space used: 1142804260 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.8 bits) S2: 57 (27.1 bits)
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