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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001012-TA|BGIBMGA001012-PA|IPR011009|Protein
kinase-like, IPR000719|Protein kinase, IPR008271|Serine/threonine
protein kinase, active site, IPR001245|Tyrosine protein kinase,
IPR002290|Serine/threonine protein kinase
         (655 letters)

Database: mosquito 
           2123 sequences; 516,269 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CR954256-9|CAJ14150.1|  872|Anopheles gambiae putative calcium/c...    95   4e-21
AJ301655-1|CAC35008.1| 1433|Anopheles gambiae putative epidermal...    68   9e-13
AY578807-1|AAT07312.1|  438|Anopheles gambiae punt protein.            58   6e-10
AY578811-1|AAT07316.1|  565|Anopheles gambiae thickveins protein.      55   5e-09
AY578798-1|AAT07303.1|  356|Anopheles gambiae baboon protein.          52   5e-08
AY578808-1|AAT07313.1|  458|Anopheles gambiae saxophone protein.       50   3e-07
AY578812-1|AAT07317.1|  932|Anopheles gambiae wishful thinking p...    43   3e-05
AJ441131-7|CAD29636.1| 1977|Anopheles gambiae putative Tyr/Ser/T...    27   2.1  
AB090821-2|BAC57918.1| 1168|Anopheles gambiae reverse transcript...    26   2.7  
AY753540-1|AAV28543.1| 3320|Anopheles gambiae SGS3 protein.            25   6.3  

>CR954256-9|CAJ14150.1|  872|Anopheles gambiae putative
           calcium/calmodulin-dependentprotein kinase, CAKI
           protein.
          Length = 872

 Score = 95.5 bits (227), Expect = 4e-21
 Identities = 81/278 (29%), Positives = 125/278 (44%), Gaps = 15/278 (5%)

Query: 354 ACKVIDTS--TAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRR-YKYFIFMRYMERG 410
           A K++D +  TA        L RE  +   L HPH+V     +      Y +F   ME  
Sbjct: 19  AVKIVDVAKFTASPGLSTSDLKREATICHMLKHPHIVELLETYSSEGMLYMVFD--MEGS 76

Query: 411 DLLEFVLQRGAV----QEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQN--- 463
           D+   V++R        E  A  + RQ+  A++Y HE +I HRD++    LL    N   
Sbjct: 77  DICFEVVRRAVAGFVYSEAVACHYLRQILEALRYCHENDIIHRDVRPACALLATADNSAP 136

Query: 464 VKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVML 523
           VKL  FG A    + + + + +    G   Y APE++    Y  KP DVW  G++++V+L
Sbjct: 137 VKLGGFGSAVQLPNGR-DSVETHGRVGCPHYMAPEVVARRVY-GKPCDVWGAGVMLHVLL 194

Query: 524 NRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVN 583
           +  +PF     K+L  A         +     IS N K L+  ML PN  +R  I ++++
Sbjct: 195 SGRLPFHGSG-KRLQDAIARGRVTLDTPEWKHISSNAKDLVLKMLAPNPISRPTITEVLD 253

Query: 584 SEWIAMDSRLLEWTPQETLAYKKAREEKNKLHKTVETV 621
             WI    +L      +T+   K    + KL   V+TV
Sbjct: 254 HPWIRDRDKLQRIHLGDTVEELKRYNARRKLKAAVQTV 291



 Score = 92.3 bits (219), Expect = 4e-20
 Identities = 76/270 (28%), Positives = 120/270 (44%), Gaps = 13/270 (4%)

Query: 50  ACKIIETAK--APKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGD 107
           A KI++ AK  A        L RE  +   L HPH++ +   +  +   Y+     E  D
Sbjct: 19  AVKIVDVAKFTASPGLSTSDLKREATICHMLKHPHIVELLETYSSEGMLYMVFDM-EGSD 77

Query: 108 LLSYILKNGCV----SENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFN---V 160
           +   +++        SE  A  + RQ+   L+Y HE +I HRD++    LL    N   V
Sbjct: 78  ICFEVVRRAVAGFVYSEAVACHYLRQILEALRYCHENDIIHRDVRPACALLATADNSAPV 137

Query: 161 KLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLN 220
           KL  FG S   + +    V +    G   Y APE++  + Y  KP D+W  GV+L V+L+
Sbjct: 138 KLGGFG-SAVQLPNGRDSVETHGRVGCPHYMAPEVVARRVY-GKPCDVWGAGVMLHVLLS 195

Query: 221 KSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDS 280
             +PF  +  R L +     +    +     +S   K +V  +L P+P  R + T VLD 
Sbjct: 196 GRLPFHGSGKR-LQDAIARGRVTLDTPEWKHISSNAKDLVLKMLAPNPISRPTITEVLDH 254

Query: 281 EWIAMDSRLTTLNAVEAAALKRAKEDRRKL 310
            WI    +L  ++  +     +    RRKL
Sbjct: 255 PWIRDRDKLQRIHLGDTVEELKRYNARRKL 284


>AJ301655-1|CAC35008.1| 1433|Anopheles gambiae putative epidermal
            growth factor receptorprotein.
          Length = 1433

 Score = 67.7 bits (158), Expect = 9e-13
 Identities = 48/213 (22%), Positives = 108/213 (50%), Gaps = 7/213 (3%)

Query: 25   VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84
            +G GA+ +V+   +  + +S K  +A K++      +    +FL  E  ++  + HP+L+
Sbjct: 840  LGMGAFGRVFKGVWMPEGESVKIPVAIKVLMEMSGSESSK-EFL-EEAYIMASVEHPNLL 897

Query: 85   HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARV-WTRQLALGLQYLHELEIA 143
             + ++    ++  +  +    G LL Y+  N     ++A + W+ Q+A G+ YL E  + 
Sbjct: 898  KLLAVCMT-SQMMLITQLMPLGCLLDYVRNNKDKIGSKALLNWSTQIARGMAYLEERRLV 956

Query: 144  HRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCP 203
            HRD+   NVL+     VK++ FG ++  ++ D+    +      + + A E +R + +  
Sbjct: 957  HRDLAARNVLVQTPSCVKITVFGLAKL-LDFDSDEYRAAGGKMPIKWLALECIRHRVFTS 1015

Query: 204  KPTDLWSLGVVLFVMLN-KSMPFDDTRMRKLYE 235
            K +D+W+ G+ ++ +L   + P+++   + + E
Sbjct: 1016 K-SDVWAFGITIWELLTYGARPYENVPAKDVPE 1047



 Score = 64.1 bits (149), Expect = 1e-11
 Identities = 45/171 (26%), Positives = 87/171 (50%), Gaps = 6/171 (3%)

Query: 369  KKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQAR 428
            K+FL  E  ++  + HP+L+   ++     +  +  + M  G LL++V         +A 
Sbjct: 879  KEFL-EEAYIMASVEHPNLLKLLAVCMTS-QMMLITQLMPLGCLLDYVRNNKDKIGSKAL 936

Query: 429  I-WTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSET 487
            + W+ Q+A  + Y+ E  + HRD+   NVL+     VK++ FG A++ +D   +E R+  
Sbjct: 937  LNWSTQIARGMAYLEERRLVHRDLAARNVLVQTPSCVKITVFGLAKL-LDFDSDEYRAAG 995

Query: 488  FCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLN-RAMPFEDKHIKQL 537
                + + A E ++   +  K +DVW+ GI ++ +L   A P+E+   K +
Sbjct: 996  GKMPIKWLALECIRHRVFTSK-SDVWAFGITIWELLTYGARPYENVPAKDV 1045


>AY578807-1|AAT07312.1|  438|Anopheles gambiae punt protein.
          Length = 438

 Score = 58.4 bits (135), Expect = 6e-10
 Identities = 54/195 (27%), Positives = 93/195 (47%), Gaps = 31/195 (15%)

Query: 70  REIDVLVRLNHPHLIHVHSIFQRK----TKYYIFMRYTENGDLLSYILKNGCVSENQARV 125
           ++I  L R+NHP+++      +R     T +++   Y ENG L  + LK   VS  +   
Sbjct: 161 QDIFKLPRMNHPNILEFIGCEKRSDMASTDFWLITAYCENGSLCDF-LKAHTVSWTELCK 219

Query: 126 WTRQLALGLQYLHEL-----------EIAHRDIKCENVLLTANFNVKLSDFGFSRFCVES 174
               +A GL +LHE             IAHRD K +NVLL A+    ++DFG +      
Sbjct: 220 IATTMARGLTHLHEEIQSSRTDGLKPSIAHRDFKSKNVLLKADLTACIADFGLALVFTPG 279

Query: 175 DNQPVLSETY--CGSMSYAAPEILRGKPYCPKPT----DLWSLGVVLFVMLNKSM----P 224
            +     +T+   G+  Y APE+L G     +      D+++ G+VL+ ++++      P
Sbjct: 280 KS---CGDTHGQVGTRRYMAPEVLEGAINFTRDAFLRIDVYACGLVLWELVSRCTVHGGP 336

Query: 225 FDDTRMRKLYEQQMG 239
            D+ R+   +E ++G
Sbjct: 337 VDEYRLP--FEAELG 349



 Score = 51.2 bits (117), Expect = 8e-08
 Identities = 43/172 (25%), Positives = 82/172 (47%), Gaps = 23/172 (13%)

Query: 374 REIEMLIKLSHPHLVHTHSIFQRR----YKYFIFMRYMERGDLLEFVLQRGAVQEDQARI 429
           ++I  L +++HP+++      +R       +++   Y E G L +F+        +  +I
Sbjct: 161 QDIFKLPRMNHPNILEFIGCEKRSDMASTDFWLITAYCENGSLCDFLKAHTVSWTELCKI 220

Query: 430 WTRQLALAIQYMHEL-----------EIAHRDIKCENVLLTANQNVKLSDFGFARMCV-D 477
            T  +A  + ++HE             IAHRD K +NVLL A+    ++DFG A +    
Sbjct: 221 ATT-MARGLTHLHEEIQSSRTDGLKPSIAHRDFKSKNVLLKADLTACIADFGLALVFTPG 279

Query: 478 KKLNEIRSETFCGSLSYTAPEILQGTPYLPKPT----DVWSLGIVVYVMLNR 525
           K   +   +   G+  Y APE+L+G     +      DV++ G+V++ +++R
Sbjct: 280 KSCGDTHGQV--GTRRYMAPEVLEGAINFTRDAFLRIDVYACGLVLWELVSR 329


>AY578811-1|AAT07316.1|  565|Anopheles gambiae thickveins protein.
          Length = 565

 Score = 55.2 bits (127), Expect = 5e-09
 Identities = 40/142 (28%), Positives = 69/142 (48%), Gaps = 15/142 (10%)

Query: 94  TKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH--------ELEIAHR 145
           T+  +   Y E G L  Y+ K   ++ +  +     LA G+ +LH        +  IAHR
Sbjct: 328 TQMLLITDYHELGSLHDYLQKR-VLNPHMLKTLAHSLASGVAHLHTEIFGTPGKPSIAHR 386

Query: 146 DIKCENVLLTANFNVKLSDFGFS-RFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCP- 203
           DIK +N+L+  N    ++DFG + ++  ESD   + + +  G+  Y APE+L        
Sbjct: 387 DIKSKNILVKRNGQCAIADFGLAVKYTSESDTIQIANNSRVGTRRYMAPEVLSETLDLNL 446

Query: 204 ----KPTDLWSLGVVLFVMLNK 221
               K  D++S+G+V + M  +
Sbjct: 447 FEGFKMADMYSVGLVFWEMARR 468



 Score = 52.8 bits (121), Expect = 3e-08
 Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 15/136 (11%)

Query: 406 YMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMH--------ELEIAHRDIKCENVL 457
           Y E G L ++ LQ+  +     +     LA  + ++H        +  IAHRDIK +N+L
Sbjct: 336 YHELGSLHDY-LQKRVLNPHMLKTLAHSLASGVAHLHTEIFGTPGKPSIAHRDIKSKNIL 394

Query: 458 LTANQNVKLSDFGFA-RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLP-----KPTD 511
           +  N    ++DFG A +   +    +I + +  G+  Y APE+L  T  L      K  D
Sbjct: 395 VKRNGQCAIADFGLAVKYTSESDTIQIANNSRVGTRRYMAPEVLSETLDLNLFEGFKMAD 454

Query: 512 VWSLGIVVYVMLNRAM 527
           ++S+G+V + M  R +
Sbjct: 455 MYSVGLVFWEMARRCI 470


>AY578798-1|AAT07303.1|  356|Anopheles gambiae baboon protein.
          Length = 356

 Score = 52.0 bits (119), Expect = 5e-08
 Identities = 40/137 (29%), Positives = 64/137 (46%), Gaps = 15/137 (10%)

Query: 94  TKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH--------ELEIAHR 145
           T+ ++   Y ENG L  ++    CV  +        +A GL +LH        +  IAHR
Sbjct: 128 TQLWLVTDYHENGSLFDFLTAR-CVDPDTMLEMAFSIATGLAHLHMDIVGTRGKPAIAHR 186

Query: 146 DIKCENVLLTANFNVKLSDFGFS-RFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCP- 203
           D+K +N+L+ +N    + D G + R  V +D     S    G+  Y APE+L        
Sbjct: 187 DLKSKNILVKSNLTCCIGDLGLAVRHIVATDTVDQPSTHRVGTKRYMAPEVLDETINVSQ 246

Query: 204 ----KPTDLWSLGVVLF 216
               K  D+++LG+VL+
Sbjct: 247 FDSFKRADVYALGLVLW 263



 Score = 46.8 bits (106), Expect = 2e-06
 Identities = 39/134 (29%), Positives = 62/134 (46%), Gaps = 15/134 (11%)

Query: 406 YMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMH--------ELEIAHRDIKCENVL 457
           Y E G L +F+  R  V  D        +A  + ++H        +  IAHRD+K +N+L
Sbjct: 136 YHENGSLFDFLTAR-CVDPDTMLEMAFSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNIL 194

Query: 458 LTANQNVKLSDFGFA-RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLP-----KPTD 511
           + +N    + D G A R  V     +  S    G+  Y APE+L  T  +      K  D
Sbjct: 195 VKSNLTCCIGDLGLAVRHIVATDTVDQPSTHRVGTKRYMAPEVLDETINVSQFDSFKRAD 254

Query: 512 VWSLGIVVYVMLNR 525
           V++LG+V++ +  R
Sbjct: 255 VYALGLVLWEIARR 268


>AY578808-1|AAT07313.1|  458|Anopheles gambiae saxophone protein.
          Length = 458

 Score = 49.6 bits (113), Expect = 3e-07
 Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 10/112 (8%)

Query: 94  TKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH--------ELEIAHR 145
           T+ ++   Y   G L  Y L    +S +Q       +A G+ +LH        +  IAHR
Sbjct: 220 TQLWLITHYYPQGSLFDY-LNRTAISTHQMITICLSIANGMVHLHTEIFGTEGKPAIAHR 278

Query: 146 DIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSET-YCGSMSYAAPEIL 196
           D+K +N+L+ AN    ++DFG +    ++ N+  +  T   G+  Y APE+L
Sbjct: 279 DLKTKNILIRANGTCVIADFGLAVMHSQTTNKIDIGNTARVGTKRYMAPEVL 330



 Score = 45.6 bits (103), Expect = 4e-06
 Identities = 34/141 (24%), Positives = 67/141 (47%), Gaps = 15/141 (10%)

Query: 401 FIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMH--------ELEIAHRDIK 452
           ++   Y  +G L ++ L R A+   Q       +A  + ++H        +  IAHRD+K
Sbjct: 223 WLITHYYPQGSLFDY-LNRTAISTHQMITICLSIANGMVHLHTEIFGTEGKPAIAHRDLK 281

Query: 453 CENVLLTANQNVKLSDFGFARM-CVDKKLNEIRSETFCGSLSYTAPEILQGTPYLP---- 507
            +N+L+ AN    ++DFG A M        +I +    G+  Y APE+L  +  +     
Sbjct: 282 TKNILIRANGTCVIADFGLAVMHSQTTNKIDIGNTARVGTKRYMAPEVLDESISMECFDA 341

Query: 508 -KPTDVWSLGIVVYVMLNRAM 527
            +  D++++G++ + +  R +
Sbjct: 342 LRKADIYAIGLIFWEVCRRTI 362


>AY578812-1|AAT07317.1|  932|Anopheles gambiae wishful thinking
           protein.
          Length = 932

 Score = 42.7 bits (96), Expect = 3e-05
 Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 14/98 (14%)

Query: 446 IAHRDIKCENVLLTANQNVKLSDFGFARMCVDKK--------LNEIRSETFCGSLSYTAP 497
           I HRD+   N+L+ ++ +  + D GFA      +        L E +S    G++ Y AP
Sbjct: 369 ICHRDLNSRNILVKSDLSCCIGDLGFALKTFGARYEYRGEITLAETKSINEVGTVRYMAP 428

Query: 498 EILQGTPYLP------KPTDVWSLGIVVYVMLNRAMPF 529
           E+L+G   L       K  DV++L +V++ + NR   F
Sbjct: 429 EVLEGAVNLRDCESALKQIDVYTLALVLWELANRCEDF 466



 Score = 41.5 bits (93), Expect = 7e-05
 Identities = 64/258 (24%), Positives = 114/258 (44%), Gaps = 44/258 (17%)

Query: 20  KLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLN 79
           KL   +G+G Y  V+      K   ++  +A KI  +A+  + F+ +   R+I  +  + 
Sbjct: 244 KLVSMIGQGKYGTVW------KGIVNEKPVAVKIF-SAQHRQYFLNE---RDIYTVPLME 293

Query: 80  HPHLIHVHSIFQRKT-----KYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
            P L+      +R+T     +Y + +     G L  ++  N        R+  + +A GL
Sbjct: 294 SPSLLAYFGSDERRTLDDRIEYMLVLSLAPLGCLQDWLTDNSVPFSTFCRMG-KSIANGL 352

Query: 135 QYLH------ELE---IAHRDIKCENVLLTANFNVKLSDFGFSRFC----VESDNQPVLS 181
            +LH      EL    I HRD+   N+L+ ++ +  + D GF+        E   +  L+
Sbjct: 353 AHLHTEIRKGELVKPCICHRDLNSRNILVKSDLSCCIGDLGFALKTFGARYEYRGEITLA 412

Query: 182 ET----YCGSMSYAAPEILRGKPY---CP---KPTDLWSLGVVLFVMLNKSMPF--DDTR 229
           ET      G++ Y APE+L G      C    K  D+++L +VL+ + N+   F  + T 
Sbjct: 413 ETKSINEVGTVRYMAPEVLEGAVNLRDCESALKQIDVYTLALVLWELANRCEDFYPEGTT 472

Query: 230 M---RKLYEQQMGKKYRF 244
           +   R  YE+ +G    F
Sbjct: 473 VPEYRAPYEEYVGSNPNF 490


>AJ441131-7|CAD29636.1| 1977|Anopheles gambiae putative Tyr/Ser/Thr
            phosphatase protein.
          Length = 1977

 Score = 26.6 bits (56), Expect = 2.1
 Identities = 13/36 (36%), Positives = 24/36 (66%), Gaps = 1/36 (2%)

Query: 609  EEKNKLHKTVETVELPGSSKTEHKV-CLPDSLVENN 643
            +E+N++ K  E   +PGSS T  K  CL ++++++N
Sbjct: 1560 DEENEVEKDKEKEGMPGSSVTAAKERCLYEAVLKHN 1595


>AB090821-2|BAC57918.1| 1168|Anopheles gambiae reverse transcriptase
           protein.
          Length = 1168

 Score = 26.2 bits (55), Expect = 2.7
 Identities = 11/23 (47%), Positives = 13/23 (56%)

Query: 149 CENVLLTANFNVKLSDFGFSRFC 171
           C  VLL  +FN    D+G SR C
Sbjct: 114 CSRVLLAGDFNAMHLDWGSSRTC 136


>AY753540-1|AAV28543.1| 3320|Anopheles gambiae SGS3 protein.
          Length = 3320

 Score = 25.0 bits (52), Expect = 6.3
 Identities = 10/30 (33%), Positives = 16/30 (53%)

Query: 433 QLALAIQYMHELEIAHRDIKCENVLLTANQ 462
           Q  L + +  E E+ H  +  ++VLL  NQ
Sbjct: 11  QQLLNVSFGDEFEVFHTQVSAQHVLLVRNQ 40


  Database: mosquito
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 516,269
  Number of sequences in database:  2123
  
Lambda     K      H
   0.320    0.135    0.400 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 681,272
Number of Sequences: 2123
Number of extensions: 27744
Number of successful extensions: 60
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 32
Number of HSP's gapped (non-prelim): 19
length of query: 655
length of database: 516,269
effective HSP length: 68
effective length of query: 587
effective length of database: 371,905
effective search space: 218308235
effective search space used: 218308235
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 51 (24.6 bits)

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