Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001012-TA|BGIBMGA001012-PA|IPR011009|Protein
kinase-like, IPR000719|Protein kinase, IPR008271|Serine/threonine
protein kinase, active site, IPR001245|Tyrosine protein kinase,
IPR002290|Serine/threonine protein kinase
(655 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000DB7284 Cluster: PREDICTED: similar to CG14305-PA... 436 e-121
UniRef50_Q17IS8 Cluster: Testis-specific serine/threonine kinase... 314 4e-84
UniRef50_Q9VE58 Cluster: CG14305-PA, isoform A; n=5; Endopterygo... 303 9e-81
UniRef50_Q17BC5 Cluster: Testis-specific serine/threonine kinase... 271 4e-71
UniRef50_Q9BXA7 Cluster: Testis-specific serine/threonine-protei... 235 2e-60
UniRef50_UPI000058436B Cluster: PREDICTED: similar to Testis-spe... 230 1e-58
UniRef50_Q172E2 Cluster: Testis-specific serine/threonine kinase... 222 2e-56
UniRef50_UPI0000D56A9A Cluster: PREDICTED: similar to CG9222-PA;... 217 1e-54
UniRef50_Q96PN8 Cluster: Testis-specific serine/threonine-protei... 212 2e-53
UniRef50_UPI0000584939 Cluster: PREDICTED: hypothetical protein;... 211 4e-53
UniRef50_A7SRN4 Cluster: Predicted protein; n=2; Nematostella ve... 209 2e-52
UniRef50_A7RKT6 Cluster: Predicted protein; n=1; Nematostella ve... 209 2e-52
UniRef50_Q9BXA6 Cluster: Testis-specific serine/threonine-protei... 204 4e-51
UniRef50_A7SGS0 Cluster: Predicted protein; n=1; Nematostella ve... 204 6e-51
UniRef50_UPI000058436C Cluster: PREDICTED: similar to Testis-spe... 204 8e-51
UniRef50_Q6SA08 Cluster: Testis-specific serine/threonine-protei... 196 2e-48
UniRef50_UPI00015B608A Cluster: PREDICTED: similar to AT03158p; ... 194 6e-48
UniRef50_UPI000155D3B2 Cluster: PREDICTED: similar to serine/thr... 192 3e-47
UniRef50_Q8T4D4 Cluster: AT03158p; n=2; Sophophora|Rep: AT03158p... 192 3e-47
UniRef50_Q7Q893 Cluster: ENSANGP00000015772; n=1; Anopheles gamb... 188 5e-46
UniRef50_UPI0000DB7653 Cluster: PREDICTED: similar to CG15072-PA... 184 9e-45
UniRef50_A7RR18 Cluster: Predicted protein; n=2; Nematostella ve... 180 8e-44
UniRef50_Q23128 Cluster: Putative uncharacterized protein; n=3; ... 180 1e-43
UniRef50_UPI0000D55D86 Cluster: PREDICTED: similar to SNF1-like ... 178 3e-43
UniRef50_Q17E44 Cluster: Map/microtubule affinity-regulating kin... 178 4e-43
UniRef50_Q16HI1 Cluster: Testis-specific serine/threonine kinase... 177 6e-43
UniRef50_Q4SL09 Cluster: Chromosome 17 SCAF14563, whole genome s... 176 1e-42
UniRef50_UPI000065EE71 Cluster: MAP/microtubule affinity-regulat... 176 2e-42
UniRef50_UPI0000E47483 Cluster: PREDICTED: similar to Testis-spe... 175 2e-42
UniRef50_Q5DTG3 Cluster: MKIAA4230 protein; n=16; Bilateria|Rep:... 175 4e-42
UniRef50_Q9VGP9 Cluster: CG6715-PA; n=7; Sophophora|Rep: CG6715-... 174 5e-42
UniRef50_A0E900 Cluster: Chromosome undetermined scaffold_83, wh... 174 7e-42
UniRef50_A7QFL3 Cluster: Chromosome chr8 scaffold_88, whole geno... 173 9e-42
UniRef50_P57059 Cluster: Serine/threonine-protein kinase SNF1-li... 173 9e-42
UniRef50_O08679 Cluster: Serine/threonine-protein kinase MARK2; ... 173 2e-41
UniRef50_Q93Y18 Cluster: SNF1 related protein kinase; n=6; rosid... 172 2e-41
UniRef50_Q7Q5I9 Cluster: ENSANGP00000004268; n=3; Culicidae|Rep:... 172 2e-41
UniRef50_A7SZV3 Cluster: Predicted protein; n=1; Nematostella ve... 172 2e-41
UniRef50_Q9W532 Cluster: CG4290-PA; n=8; Coelomata|Rep: CG4290-P... 171 4e-41
UniRef50_O61821 Cluster: Temporarily assigned gene name protein ... 171 4e-41
UniRef50_Q9P0L2 Cluster: Serine/threonine-protein kinase MARK1; ... 171 4e-41
UniRef50_Q96L34 Cluster: MAP/microtubule affinity-regulating kin... 171 7e-41
UniRef50_Q9H093 Cluster: NUAK family SNF1-like kinase 2; n=31; E... 169 2e-40
UniRef50_Q7R9H7 Cluster: Serine/threonine-protein kinase; n=3; P... 169 3e-40
UniRef50_Q6P4S6 Cluster: Serine/threonine-protein kinase QSK; n=... 169 3e-40
UniRef50_Q9Y2K2 Cluster: Serine/threonine-protein kinase QSK; n=... 169 3e-40
UniRef50_Q8MVX2 Cluster: Putative serine/threonine protein kinas... 168 4e-40
UniRef50_UPI0000E4986C Cluster: PREDICTED: similar to KIAA0999 p... 167 6e-40
UniRef50_Q22SK1 Cluster: Protein kinase domain containing protei... 167 6e-40
UniRef50_UPI00015B41D5 Cluster: PREDICTED: hypothetical protein;... 167 8e-40
UniRef50_A0D0C4 Cluster: Chromosome undetermined scaffold_33, wh... 167 8e-40
UniRef50_A0CKQ4 Cluster: Chromosome undetermined scaffold_2, who... 167 8e-40
UniRef50_UPI00003C0E92 Cluster: PREDICTED: similar to CG4290-PA;... 166 1e-39
UniRef50_Q22XQ2 Cluster: Protein kinase domain containing protei... 166 2e-39
UniRef50_Q9FJ55 Cluster: Serine/threonine protein kinase; n=14; ... 165 3e-39
UniRef50_A2EBI4 Cluster: CAMK family protein kinase; n=1; Tricho... 165 4e-39
UniRef50_A0E1E2 Cluster: Chromosome undetermined scaffold_73, wh... 165 4e-39
UniRef50_Q65ZH3 Cluster: Putative uncharacterized protein; n=4; ... 164 8e-39
UniRef50_Q21017 Cluster: Protein kinase protein 29; n=2; Caenorh... 164 8e-39
UniRef50_Q6NSM8 Cluster: Serine/threonine-protein kinase QSK hom... 164 8e-39
UniRef50_Q1MTK5 Cluster: Novel protein containing a protein kina... 163 1e-38
UniRef50_Q9MAM1 Cluster: T25K16.13; n=9; Brassicaceae|Rep: T25K1... 163 1e-38
UniRef50_A2X165 Cluster: Putative uncharacterized protein; n=2; ... 163 1e-38
UniRef50_P92937 Cluster: CBL-interacting serine/threonine-protei... 163 1e-38
UniRef50_A2ETF3 Cluster: CAMK family protein kinase; n=1; Tricho... 163 1e-38
UniRef50_P54646 Cluster: 5'-AMP-activated protein kinase catalyt... 163 1e-38
UniRef50_UPI0000D56584 Cluster: PREDICTED: similar to CG15072-PA... 163 2e-38
UniRef50_A7QA52 Cluster: Chromosome undetermined scaffold_69, wh... 163 2e-38
UniRef50_Q7R0B9 Cluster: GLP_608_36888_34957; n=1; Giardia lambl... 163 2e-38
UniRef50_A0BCL5 Cluster: Chromosome undetermined scaffold_10, wh... 163 2e-38
UniRef50_Q54DF2 Cluster: Putative uncharacterized protein mrkA; ... 162 3e-38
UniRef50_Q8RWC9 Cluster: CBL-interacting serine/threonine-protei... 162 3e-38
UniRef50_Q9SLZ5 Cluster: OsPK7; n=14; Magnoliophyta|Rep: OsPK7 -... 161 4e-38
UniRef50_A2FHU2 Cluster: CAMK family protein kinase; n=1; Tricho... 161 4e-38
UniRef50_A4RL66 Cluster: Putative uncharacterized protein; n=4; ... 161 4e-38
UniRef50_A2DBY9 Cluster: CAMK family protein kinase; n=2; Tricho... 160 9e-38
UniRef50_P25323 Cluster: Myosin light chain kinase; n=4; Dictyos... 160 1e-37
UniRef50_Q38997 Cluster: SNF1-related protein kinase catalytic s... 160 1e-37
UniRef50_Q0KI87 Cluster: CG11870-PA, isoform A; n=3; Drosophila ... 159 2e-37
UniRef50_A2EQQ4 Cluster: CAMK family protein kinase; n=1; Tricho... 159 2e-37
UniRef50_Q9H0K1 Cluster: Serine/threonine-protein kinase SNF1-li... 159 2e-37
UniRef50_UPI00006CBF34 Cluster: Protein kinase domain containing... 159 3e-37
UniRef50_Q9Y7V4 Cluster: Serine threonine protein kinase; n=5; F... 159 3e-37
UniRef50_A2EN63 Cluster: CAMK family protein kinase; n=2; Tricho... 158 4e-37
UniRef50_UPI0000D56F77 Cluster: PREDICTED: similar to CG11870-PA... 158 5e-37
UniRef50_A2DHV0 Cluster: CAMK family protein kinase; n=1; Tricho... 157 7e-37
UniRef50_A5DM85 Cluster: Putative uncharacterized protein; n=1; ... 157 7e-37
UniRef50_O60285 Cluster: NUAK family SNF1-like kinase 1; n=16; E... 157 7e-37
UniRef50_A3FPS4 Cluster: OSK4, putative; n=2; Cryptosporidium|Re... 157 9e-37
UniRef50_UPI000049980F Cluster: protein kinase; n=1; Entamoeba h... 157 1e-36
UniRef50_UPI000069E3DA Cluster: UPI000069E3DA related cluster; n... 157 1e-36
UniRef50_Q4SUX6 Cluster: Chromosome undetermined SCAF13836, whol... 157 1e-36
UniRef50_Q26018 Cluster: Serine/threonine-protein kinase; n=2; P... 157 1e-36
UniRef50_Q1HGK2 Cluster: SNF1; n=3; Pezizomycotina|Rep: SNF1 - M... 157 1e-36
UniRef50_A5E3E1 Cluster: Putative uncharacterized protein; n=1; ... 157 1e-36
UniRef50_A3LVN1 Cluster: Predicted protein; n=1; Pichia stipitis... 157 1e-36
UniRef50_UPI0001560DD3 Cluster: PREDICTED: similar to MAP/microt... 156 2e-36
UniRef50_A2E7E2 Cluster: CAMK family protein kinase; n=1; Tricho... 156 2e-36
UniRef50_O22932 Cluster: CBL-interacting serine/threonine-protei... 156 2e-36
UniRef50_Q8TDC3 Cluster: BR serine/threonine-protein kinase 1; n... 156 2e-36
UniRef50_UPI0000E21E7B Cluster: PREDICTED: maternal embryonic le... 156 2e-36
UniRef50_A2ENP4 Cluster: CAMK family protein kinase; n=1; Tricho... 156 2e-36
UniRef50_Q94DT7 Cluster: OsPK4-like protein; n=4; Oryza sativa|R... 155 3e-36
UniRef50_Q84QE0 Cluster: Avr9/Cf-9 rapidly elicited protein 216;... 155 3e-36
UniRef50_A2EA15 Cluster: CAMK family protein kinase; n=1; Tricho... 155 3e-36
UniRef50_O18645 Cluster: CG3051-PA, isoform A; n=9; Coelomata|Re... 155 4e-36
UniRef50_Q8SW31 Cluster: Similarity to SER/THR PROTEIN KINASE KI... 155 4e-36
UniRef50_Q5AG71 Cluster: Potential serine/threonine-protein kina... 155 4e-36
UniRef50_P06782 Cluster: Carbon catabolite-derepressing protein ... 155 4e-36
UniRef50_A7Q6M5 Cluster: Chromosome chr11 scaffold_56, whole gen... 155 5e-36
UniRef50_A0DEL1 Cluster: Chromosome undetermined scaffold_48, wh... 155 5e-36
UniRef50_Q55H99 Cluster: Putative uncharacterized protein; n=2; ... 155 5e-36
UniRef50_Q98RL9 Cluster: SNF-related kinase; n=1; Guillardia the... 154 6e-36
UniRef50_Q6BFK9 Cluster: SNF1-related protein kinase, putative; ... 154 6e-36
UniRef50_A2F029 Cluster: CAMK family protein kinase; n=3; Tricho... 154 6e-36
UniRef50_A2E705 Cluster: CAMK family protein kinase; n=1; Tricho... 154 6e-36
UniRef50_A0CGU4 Cluster: Chromosome undetermined scaffold_18, wh... 154 6e-36
UniRef50_Q09170 Cluster: Serine/threonine-protein kinase cds1; n... 154 6e-36
UniRef50_A2EUJ6 Cluster: CAMK family protein kinase; n=1; Tricho... 154 8e-36
UniRef50_Q7R2W2 Cluster: GLP_291_14488_15897; n=1; Giardia lambl... 153 1e-35
UniRef50_A2GAV1 Cluster: CAMK family protein kinase; n=1; Tricho... 153 1e-35
UniRef50_A0EBP2 Cluster: Chromosome undetermined scaffold_88, wh... 153 1e-35
UniRef50_Q14680 Cluster: Maternal embryonic leucine zipper kinas... 153 1e-35
UniRef50_Q8IWQ3 Cluster: BR serine/threonine-protein kinase 2; n... 153 1e-35
UniRef50_UPI0000519D29 Cluster: PREDICTED: similar to maternal e... 153 2e-35
UniRef50_Q7QBH3 Cluster: ENSANGP00000014786; n=3; Culicidae|Rep:... 153 2e-35
UniRef50_A4I4Q9 Cluster: Serine/threonine protein kinase, putati... 153 2e-35
UniRef50_Q17M45 Cluster: Br serine/threonine-protein kinase; n=2... 152 2e-35
UniRef50_UPI0000DA406D Cluster: PREDICTED: similar to serine/thr... 152 3e-35
UniRef50_A2GCT3 Cluster: CAMK family protein kinase; n=1; Tricho... 152 3e-35
UniRef50_A2FMX7 Cluster: CAMK family protein kinase; n=2; Tricho... 152 3e-35
UniRef50_A2EZM5 Cluster: AGC family protein kinase; n=1; Trichom... 152 3e-35
UniRef50_A2E6I9 Cluster: AGC family protein kinase; n=2; Trichom... 152 3e-35
UniRef50_UPI000155CFAD Cluster: PREDICTED: hypothetical protein;... 151 4e-35
UniRef50_Q4SW69 Cluster: Chromosome 9 SCAF13686, whole genome sh... 151 4e-35
UniRef50_Q4QIJ7 Cluster: Serine/threonine kinase, putative; n=13... 151 4e-35
UniRef50_A2FDI8 Cluster: CAMK family protein kinase; n=1; Tricho... 151 4e-35
UniRef50_Q59W62 Cluster: Likely protein kinase; n=2; Candida alb... 151 4e-35
UniRef50_UPI0000660272 Cluster: Homolog of Homo sapiens "MAP/mic... 151 6e-35
UniRef50_Q6BG36 Cluster: SNF1-related protein kinase, putative; ... 151 6e-35
UniRef50_A2ET53 Cluster: CAMK family protein kinase; n=1; Tricho... 151 6e-35
UniRef50_A2DBR9 Cluster: CAMK family protein kinase; n=1; Tricho... 151 6e-35
UniRef50_Q6CAK0 Cluster: Yarrowia lipolytica chromosome D of str... 151 6e-35
UniRef50_Q9VUV4 Cluster: CG6114-PA; n=2; Drosophila melanogaster... 151 8e-35
UniRef50_Q3LDS4 Cluster: Carbon catabolite derepressing protein ... 150 1e-34
UniRef50_O61298 Cluster: HrPOPK-1 protein; n=2; Coelomata|Rep: H... 150 1e-34
UniRef50_A2EZM7 Cluster: CAMK family protein kinase; n=1; Tricho... 150 1e-34
UniRef50_A2DP40 Cluster: CAMK family protein kinase; n=2; Tricho... 150 1e-34
UniRef50_A2DHM8 Cluster: CAMK family protein kinase; n=1; Tricho... 150 1e-34
UniRef50_A5DU66 Cluster: Putative uncharacterized protein; n=2; ... 150 1e-34
UniRef50_P22987 Cluster: Protein kinase kin1; n=1; Schizosacchar... 150 1e-34
UniRef50_UPI00015B5491 Cluster: PREDICTED: similar to br serine/... 150 1e-34
UniRef50_A2FK34 Cluster: CAMK family protein kinase; n=2; Tricho... 150 1e-34
UniRef50_A0E8Y3 Cluster: Chromosome undetermined scaffold_83, wh... 150 1e-34
UniRef50_A0E675 Cluster: Chromosome undetermined scaffold_8, who... 150 1e-34
UniRef50_A0DFC5 Cluster: Chromosome undetermined scaffold_49, wh... 150 1e-34
UniRef50_Q75DQ1 Cluster: ABL034Wp; n=1; Eremothecium gossypii|Re... 150 1e-34
UniRef50_UPI0000F20BD0 Cluster: PREDICTED: hypothetical protein;... 149 2e-34
UniRef50_Q4RVL2 Cluster: Chromosome 15 SCAF14992, whole genome s... 149 2e-34
UniRef50_Q240T9 Cluster: Protein kinase domain containing protei... 149 2e-34
UniRef50_Q19962 Cluster: Putative uncharacterized protein; n=3; ... 149 2e-34
UniRef50_Q6M929 Cluster: Related to serine/threonine-specific pr... 149 2e-34
UniRef50_Q2KFW9 Cluster: Putative uncharacterized protein; n=2; ... 149 2e-34
UniRef50_Q9BYT3 Cluster: Serine/threonine-protein kinase 33; n=2... 149 2e-34
UniRef50_UPI0000F2C213 Cluster: PREDICTED: hypothetical protein;... 149 2e-34
UniRef50_UPI000049A5C0 Cluster: protein kinase; n=1; Entamoeba h... 149 2e-34
UniRef50_UPI00015B5903 Cluster: PREDICTED: similar to Melk prote... 149 3e-34
UniRef50_UPI0000E49D63 Cluster: PREDICTED: similar to hormonally... 149 3e-34
UniRef50_Q95UF4 Cluster: Serine-threonine protein kinase; n=1; A... 149 3e-34
UniRef50_A2EP88 Cluster: CAMK family protein kinase; n=1; Tricho... 149 3e-34
UniRef50_Q7Z865 Cluster: Protein kinase; n=1; Kluyveromyces lact... 149 3e-34
UniRef50_A7TMR5 Cluster: Putative uncharacterized protein; n=1; ... 149 3e-34
UniRef50_P45894 Cluster: 5'-AMP-activated protein kinase catalyt... 149 3e-34
UniRef50_UPI0000583D61 Cluster: PREDICTED: similar to Tssk5 prot... 148 4e-34
UniRef50_UPI000023D36F Cluster: hypothetical protein FG08701.1; ... 148 4e-34
UniRef50_A5K3L6 Cluster: Serine/threonine-protein kinase, putati... 148 4e-34
UniRef50_A2FGW3 Cluster: CAMK family protein kinase; n=1; Tricho... 148 4e-34
UniRef50_A2EKR5 Cluster: CAMK family protein kinase; n=3; Tricho... 148 4e-34
UniRef50_P57058 Cluster: Hormonally up-regulated neu tumor-assoc... 148 4e-34
UniRef50_UPI00002495CF Cluster: PREDICTED: similar to NUAK famil... 148 5e-34
UniRef50_Q170I9 Cluster: Serine/threonine protein kinase; n=3; C... 148 5e-34
UniRef50_Q7SCT1 Cluster: Putative uncharacterized protein NCU090... 148 5e-34
UniRef50_Q6CUX0 Cluster: Similar to sp|Q12263 Saccharomyces cere... 148 5e-34
UniRef50_Q6BR88 Cluster: Similar to CA5851|CaKIN2 Candida albica... 148 5e-34
UniRef50_Q96NX5 Cluster: Calcium/calmodulin-dependent protein ki... 148 5e-34
UniRef50_UPI00015B507B Cluster: PREDICTED: similar to cell cycle... 147 7e-34
UniRef50_A2ERA7 Cluster: CAMK family protein kinase; n=1; Tricho... 147 7e-34
UniRef50_A2D7H7 Cluster: CAMK family protein kinase; n=1; Tricho... 147 7e-34
UniRef50_Q6CJD2 Cluster: Similar to sp|P13186 Saccharomyces cere... 147 7e-34
UniRef50_Q2U7N6 Cluster: Serine/threonine protein kinase; n=8; E... 147 7e-34
UniRef50_UPI00006CFC37 Cluster: Protein kinase domain containing... 147 9e-34
UniRef50_Q54VI1 Cluster: Putative uncharacterized protein fhkE; ... 147 9e-34
UniRef50_Q22S16 Cluster: Protein kinase domain containing protei... 147 9e-34
UniRef50_Q22M67 Cluster: Protein kinase domain containing protei... 147 9e-34
UniRef50_UPI00006CFA8B Cluster: Protein kinase domain containing... 146 1e-33
UniRef50_UPI0000548690 Cluster: PREDICTED: hypothetical protein;... 146 1e-33
UniRef50_A2DI34 Cluster: CAMK family protein kinase; n=2; Tricho... 146 1e-33
UniRef50_A7TFG1 Cluster: Putative uncharacterized protein; n=1; ... 146 1e-33
UniRef50_UPI00015A5AA6 Cluster: UPI00015A5AA6 related cluster; n... 146 2e-33
UniRef50_A2DRR6 Cluster: CAMK family protein kinase; n=1; Tricho... 146 2e-33
UniRef50_Q9UAY1 Cluster: Putative uncharacterized protein; n=5; ... 146 2e-33
UniRef50_Q7R4G4 Cluster: GLP_49_88961_90850; n=1; Giardia lambli... 146 2e-33
UniRef50_Q54CY9 Cluster: Putative uncharacterized protein; n=1; ... 146 2e-33
UniRef50_A2E194 Cluster: CAMK family protein kinase; n=1; Tricho... 146 2e-33
UniRef50_A2DTF0 Cluster: CAMK family protein kinase; n=1; Tricho... 146 2e-33
UniRef50_Q6BPF2 Cluster: Similar to CA4097|CaGIN4 Candida albica... 146 2e-33
UniRef50_Q9LDI3 Cluster: CBL-interacting serine/threonine-protei... 146 2e-33
UniRef50_Q4E3J2 Cluster: Serine/threonine protein kinase, putati... 145 3e-33
UniRef50_O17879 Cluster: Putative uncharacterized protein; n=2; ... 145 3e-33
UniRef50_A2F3L4 Cluster: CAMK family protein kinase; n=1; Tricho... 145 3e-33
UniRef50_A4IFZ4 Cluster: LOC565828 protein; n=2; Euteleostomi|Re... 145 4e-33
UniRef50_A5DRU5 Cluster: Putative uncharacterized protein; n=1; ... 145 4e-33
UniRef50_Q12263 Cluster: Serine/threonine-protein kinase GIN4; n... 145 4e-33
UniRef50_UPI00006CA3B2 Cluster: Protein kinase domain containing... 144 5e-33
UniRef50_Q4SAD5 Cluster: Chromosome 13 SCAF14688, whole genome s... 144 5e-33
UniRef50_Q5Z6X0 Cluster: Putative wpk4 protein kinase; n=4; Oryz... 144 5e-33
UniRef50_A7RVS7 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 144 5e-33
UniRef50_A2F749 Cluster: CAMK family protein kinase; n=1; Tricho... 144 5e-33
UniRef50_A3LNK1 Cluster: Predicted protein; n=1; Pichia stipitis... 144 5e-33
UniRef50_O74536 Cluster: SNF1-like protein kinase ssp2; n=3; Sch... 144 5e-33
UniRef50_Q7ZU72 Cluster: Maternal embryonic leucine zipper kinas... 144 7e-33
UniRef50_Q4RK91 Cluster: Chromosome 18 SCAF15030, whole genome s... 144 7e-33
UniRef50_Q54PB4 Cluster: Putative uncharacterized protein; n=1; ... 144 7e-33
UniRef50_A2ESJ5 Cluster: CAMK family protein kinase; n=1; Tricho... 144 7e-33
UniRef50_A0DBM2 Cluster: Chromosome undetermined scaffold_44, wh... 144 7e-33
UniRef50_P22216 Cluster: Serine/threonine-protein kinase RAD53; ... 144 7e-33
UniRef50_UPI0001561451 Cluster: PREDICTED: similar to serine/thr... 144 9e-33
UniRef50_A2QQQ6 Cluster: Function: S. pombe kin1 affects composi... 144 9e-33
UniRef50_P13186 Cluster: Serine/threonine-protein kinase KIN2; n... 144 9e-33
UniRef50_UPI0000E801CD Cluster: PREDICTED: hypothetical protein;... 143 1e-32
UniRef50_Q4RWR4 Cluster: Chromosome 15 SCAF14981, whole genome s... 143 1e-32
UniRef50_A2E0G9 Cluster: Protein kinase, putative; n=4; Trichomo... 143 1e-32
UniRef50_UPI0000F2D863 Cluster: PREDICTED: hypothetical protein;... 143 2e-32
UniRef50_A7TRN0 Cluster: Putative uncharacterized protein; n=1; ... 143 2e-32
UniRef50_Q8IY84 Cluster: Serine/threonine-protein kinase NIM1; n... 143 2e-32
UniRef50_P13185 Cluster: Protein kinase KIN1; n=2; Saccharomyces... 143 2e-32
UniRef50_UPI000049857F Cluster: protein kinase; n=1; Entamoeba h... 142 2e-32
UniRef50_Q960G5 Cluster: SD02969p; n=4; Sophophora|Rep: SD02969p... 142 2e-32
UniRef50_A2DWE7 Cluster: CAMK family protein kinase; n=1; Tricho... 142 2e-32
UniRef50_Q75CE9 Cluster: ACR142Wp; n=1; Eremothecium gossypii|Re... 142 2e-32
UniRef50_Q5K995 Cluster: Protein kinase kin1, putative; n=2; Fil... 142 2e-32
UniRef50_UPI00006D00D8 Cluster: Protein kinase domain containing... 142 3e-32
UniRef50_A2EFB7 Cluster: CAMK family protein kinase; n=1; Tricho... 142 3e-32
UniRef50_Q6BTQ3 Cluster: Similar to CA2348|IPF12811 Candida albi... 142 3e-32
UniRef50_Q4P2M4 Cluster: Putative uncharacterized protein; n=1; ... 142 3e-32
UniRef50_Q98SC8 Cluster: SNF1-related protein kinase; n=1; Guill... 142 4e-32
UniRef50_Q3I4W2 Cluster: Putative serine/threonine protein kinas... 142 4e-32
UniRef50_A2ESP5 Cluster: CAMK family protein kinase; n=1; Tricho... 142 4e-32
UniRef50_A0BZI1 Cluster: Chromosome undetermined scaffold_139, w... 142 4e-32
UniRef50_A0BX79 Cluster: Chromosome undetermined scaffold_134, w... 142 4e-32
UniRef50_Q5AAI1 Cluster: Likely protein kinase; n=1; Candida alb... 142 4e-32
UniRef50_A3LS04 Cluster: [Hydroxymethylglutaryl-CoA reductase(NA... 142 4e-32
UniRef50_O59697 Cluster: Serine/threonine-protein kinase ppk25; ... 142 4e-32
UniRef50_Q6P954 Cluster: Zgc:73231; n=2; Danio rerio|Rep: Zgc:73... 141 5e-32
UniRef50_Q9SEZ7 Cluster: CBL-interacting protein kinase 16; n=10... 141 5e-32
UniRef50_Q2QMI0 Cluster: Protein kinase domain containing protei... 141 5e-32
UniRef50_Q7QXR8 Cluster: GLP_399_8255_9553; n=1; Giardia lamblia... 141 5e-32
UniRef50_A2G7K5 Cluster: CAMK family protein kinase; n=1; Tricho... 141 5e-32
UniRef50_A0DMA4 Cluster: Chromosome undetermined scaffold_56, wh... 141 5e-32
UniRef50_Q6FXC9 Cluster: Candida glabrata strain CBS138 chromoso... 141 5e-32
UniRef50_Q6FIV8 Cluster: Similar to sp|P13186 Saccharomyces cere... 141 5e-32
UniRef50_Q4WND7 Cluster: Serine/threonine protein kinase, putati... 141 5e-32
UniRef50_A5DPM3 Cluster: Putative uncharacterized protein; n=1; ... 141 5e-32
UniRef50_A2EU91 Cluster: CAMK family protein kinase; n=2; Tricho... 141 6e-32
UniRef50_A2EI57 Cluster: CAMK family protein kinase; n=2; Tricho... 141 6e-32
UniRef50_A2E5K8 Cluster: AGC family protein kinase; n=1; Trichom... 141 6e-32
UniRef50_A2DUF1 Cluster: CAMK family protein kinase; n=2; Tricho... 141 6e-32
UniRef50_A2DEB4 Cluster: CAMK family protein kinase; n=1; Tricho... 141 6e-32
UniRef50_A0DUI6 Cluster: Chromosome undetermined scaffold_64, wh... 141 6e-32
UniRef50_Q8J2N0 Cluster: Protein kinase SNF1; n=2; Hypocreales|R... 141 6e-32
UniRef50_A5DKR9 Cluster: Putative uncharacterized protein; n=1; ... 141 6e-32
UniRef50_P34244 Cluster: Probable serine/threonine-protein kinas... 141 6e-32
UniRef50_Q9P0L2-3 Cluster: Isoform 3 of Q9P0L2 ; n=3; Homo sapie... 140 8e-32
UniRef50_A2GCI0 Cluster: CAMK family protein kinase; n=1; Tricho... 140 8e-32
UniRef50_A2EWC2 Cluster: CAMK family protein kinase; n=1; Tricho... 140 8e-32
UniRef50_A2D9H3 Cluster: CAMK family protein kinase; n=1; Tricho... 140 8e-32
UniRef50_Q59UZ0 Cluster: Likely protein kinase; n=2; Saccharomyc... 140 8e-32
UniRef50_P11801 Cluster: Serine/threonine-protein kinase H1; n=3... 140 8e-32
UniRef50_UPI000155F8D7 Cluster: PREDICTED: similar to MAP/microt... 140 1e-31
UniRef50_UPI000155511B Cluster: PREDICTED: similar to Calcium/ca... 140 1e-31
UniRef50_Q4RSJ0 Cluster: Chromosome 13 SCAF15000, whole genome s... 140 1e-31
UniRef50_Q9BMX6 Cluster: Phosphoinositide-dependent protein kina... 140 1e-31
UniRef50_Q26334 Cluster: Serine/threonine protein kinase; n=2; E... 140 1e-31
UniRef50_A2DKX0 Cluster: CAMK family protein kinase; n=1; Tricho... 140 1e-31
UniRef50_A2D8W5 Cluster: CAMK family protein kinase; n=1; Tricho... 140 1e-31
UniRef50_A0CJY8 Cluster: Chromosome undetermined scaffold_2, who... 140 1e-31
UniRef50_P25389 Cluster: Probable serine/threonine-protein kinas... 140 1e-31
UniRef50_UPI0000F2C92F Cluster: PREDICTED: similar to serine/thr... 140 1e-31
UniRef50_UPI00004990CF Cluster: protein kinase; n=1; Entamoeba h... 140 1e-31
UniRef50_Q54TA3 Cluster: Putative uncharacterized protein mrkC; ... 140 1e-31
UniRef50_Q17E90 Cluster: Serine/threonine protein kinase; n=4; E... 140 1e-31
UniRef50_A7API5 Cluster: Protein kinase domain containing protei... 140 1e-31
UniRef50_A2EE93 Cluster: AGC family protein kinase; n=1; Trichom... 140 1e-31
UniRef50_A0DV61 Cluster: Chromosome undetermined scaffold_65, wh... 140 1e-31
UniRef50_UPI00005846CE Cluster: PREDICTED: hypothetical protein;... 139 2e-31
UniRef50_Q247W3 Cluster: Protein kinase domain containing protei... 139 2e-31
UniRef50_A2FLT8 Cluster: CAMK family protein kinase; n=1; Tricho... 139 2e-31
UniRef50_A2D7M3 Cluster: CAMK family protein kinase; n=1; Tricho... 139 2e-31
UniRef50_Q8N2N5 Cluster: CDNA FLJ90097 fis, clone HEMBA1005929, ... 139 2e-31
UniRef50_Q5KCH7 Cluster: Calmodulin-dependent protein kinase I, ... 139 2e-31
UniRef50_UPI0000D57368 Cluster: PREDICTED: similar to CG8485-PA,... 139 2e-31
UniRef50_UPI00005464B8 Cluster: PREDICTED: similar to Ca2+/calmo... 139 2e-31
UniRef50_Q8IKX5 Cluster: Protein kinase, putative; n=7; Plasmodi... 139 2e-31
UniRef50_A2DMH0 Cluster: CAMK family protein kinase; n=3; Tricho... 139 2e-31
UniRef50_Q8C1R0 Cluster: Testis-specific serine/threonine-protei... 139 2e-31
UniRef50_Q8IU85 Cluster: Calcium/calmodulin-dependent protein ki... 139 2e-31
UniRef50_UPI0000D564B7 Cluster: PREDICTED: similar to protein ki... 138 3e-31
UniRef50_UPI00004998A1 Cluster: protein kinase; n=1; Entamoeba h... 138 3e-31
UniRef50_Q8S9G0 Cluster: SNF1-related protein kinase; n=2; BEP c... 138 3e-31
UniRef50_Q6ZL03 Cluster: Putative SnRK1b protein kinase; n=3; Or... 138 3e-31
UniRef50_Q869W6 Cluster: Similar to Xenopus laevis (African claw... 138 3e-31
UniRef50_A2FJN1 Cluster: CAMK family protein kinase; n=1; Tricho... 138 3e-31
UniRef50_A0E1C0 Cluster: Chromosome undetermined scaffold_73, wh... 138 3e-31
UniRef50_A0CTT3 Cluster: Chromosome undetermined scaffold_27, wh... 138 3e-31
UniRef50_A0CJ09 Cluster: Chromosome undetermined scaffold_19, wh... 138 3e-31
UniRef50_Q5K9K6 Cluster: Serine/threonine-protein kinase, putati... 138 3e-31
UniRef50_Q4RRU3 Cluster: Chromosome 7 SCAF15001, whole genome sh... 138 4e-31
UniRef50_Q9TXI1 Cluster: Putative uncharacterized protein F23C8.... 138 4e-31
UniRef50_Q6BFD3 Cluster: Calcium-dependent protein kinase, putat... 138 4e-31
UniRef50_A2FZR5 Cluster: CAMK family protein kinase; n=1; Tricho... 138 4e-31
UniRef50_A2F807 Cluster: CAMK family protein kinase; n=1; Tricho... 138 4e-31
UniRef50_Q6FMF3 Cluster: Candida glabrata strain CBS138 chromoso... 138 4e-31
UniRef50_Q761X0 Cluster: Putative uncharacterized protein; n=2; ... 138 6e-31
UniRef50_A4HHQ5 Cluster: Serine/threonine-protein kinase, putati... 138 6e-31
UniRef50_A0CEB3 Cluster: Chromosome undetermined scaffold_170, w... 138 6e-31
UniRef50_Q74ZZ9 Cluster: AGR058Wp; n=1; Eremothecium gossypii|Re... 138 6e-31
UniRef50_Q39030 Cluster: Serine/threonine-protein kinase AtPK19;... 138 6e-31
UniRef50_UPI000150A7D8 Cluster: Protein kinase domain containing... 137 8e-31
UniRef50_UPI00006CBD49 Cluster: Protein kinase domain containing... 137 8e-31
UniRef50_A1A5Q6 Cluster: RGD1562638_predicted protein; n=6; Muri... 137 8e-31
UniRef50_Q84VQ2 Cluster: Protein kinase family; n=4; core eudico... 137 8e-31
UniRef50_Q9VPW3 Cluster: CG4629-PA, isoform A; n=3; Sophophora|R... 137 8e-31
UniRef50_Q761X1 Cluster: Putative uncharacterized protein; n=1; ... 137 8e-31
UniRef50_Q5CXM0 Cluster: Ser/Thr protein kinase; n=2; Cryptospor... 137 8e-31
UniRef50_Q4Q1Y6 Cluster: Protein kinase, putative; n=3; Leishman... 137 8e-31
UniRef50_A2FBN8 Cluster: CAMK family protein kinase; n=2; Tricho... 137 8e-31
UniRef50_A2EJ14 Cluster: CAMK family protein kinase; n=1; Tricho... 137 8e-31
UniRef50_Q5KEQ4 Cluster: SNF1A/AMP-activated protein kinase, put... 137 8e-31
UniRef50_A3LNW8 Cluster: Predicted protein; n=5; Saccharomycetal... 137 8e-31
UniRef50_UPI0000DA22CE Cluster: PREDICTED: similar to serine/thr... 137 1e-30
UniRef50_UPI00006CB13C Cluster: Protein kinase domain containing... 137 1e-30
UniRef50_Q94CG0 Cluster: CBL-interacting protein kinase 21; n=4;... 137 1e-30
UniRef50_A2EWI0 Cluster: AGC family protein kinase; n=2; Trichom... 137 1e-30
UniRef50_Q9NRH2 Cluster: SNF-related serine/threonine-protein ki... 137 1e-30
UniRef50_A2GB48 Cluster: CAMK family protein kinase; n=1; Tricho... 136 1e-30
UniRef50_A2G0N4 Cluster: CAMK family protein kinase; n=1; Tricho... 136 1e-30
UniRef50_A2E0S1 Cluster: CAMK family protein kinase; n=1; Tricho... 136 1e-30
UniRef50_A0DMG4 Cluster: Chromosome undetermined scaffold_56, wh... 136 1e-30
UniRef50_A0BXP1 Cluster: Chromosome undetermined scaffold_135, w... 136 1e-30
UniRef50_Q59EH6 Cluster: 3-phosphoinositide dependent protein ki... 136 1e-30
UniRef50_Q59TB3 Cluster: Likely protein kinase; n=1; Candida alb... 136 1e-30
UniRef50_Q2UMC9 Cluster: Serine/threonine protein kinase; n=6; P... 136 1e-30
UniRef50_O15530 Cluster: 3-phosphoinositide-dependent protein ki... 136 1e-30
UniRef50_Q4SFY0 Cluster: Chromosome 7 SCAF14601, whole genome sh... 136 2e-30
UniRef50_Q4E096 Cluster: Protein kinase, putative; n=2; Trypanos... 136 2e-30
UniRef50_A2EPI6 Cluster: CAMK family protein kinase; n=1; Tricho... 136 2e-30
UniRef50_Q6C4Q4 Cluster: Similar to tr|Q12152 Saccharomyces cere... 136 2e-30
UniRef50_Q0D3M5 Cluster: Os07g0678300 protein; n=3; Oryza sativa... 136 2e-30
UniRef50_Q7RTG4 Cluster: Myosin light chain kinase; n=5; Plasmod... 136 2e-30
UniRef50_Q2PJ68 Cluster: Putative uncharacterized protein sgk-1;... 136 2e-30
UniRef50_A0DWU2 Cluster: Chromosome undetermined scaffold_67, wh... 136 2e-30
UniRef50_Q9UK32 Cluster: Ribosomal protein S6 kinase alpha-6; n=... 136 2e-30
UniRef50_Q22DW7 Cluster: Protein kinase domain containing protei... 135 3e-30
UniRef50_A2DNV1 Cluster: CAMK family protein kinase; n=1; Tricho... 135 3e-30
UniRef50_Q4P7I5 Cluster: Putative uncharacterized protein; n=1; ... 135 3e-30
UniRef50_Q0UXH7 Cluster: Putative uncharacterized protein; n=1; ... 135 3e-30
UniRef50_O61267 Cluster: Ovarian-specific serine/threonine-prote... 135 3e-30
UniRef50_UPI00006CB772 Cluster: Protein kinase domain containing... 135 4e-30
UniRef50_A2AQX6 Cluster: Novel protein tyrosine kinase; n=2; Mus... 135 4e-30
UniRef50_Q7Q4D2 Cluster: ENSANGP00000019651; n=1; Anopheles gamb... 135 4e-30
UniRef50_Q4Q416 Cluster: Protein kinase, putative; n=6; Trypanos... 135 4e-30
UniRef50_Q22RU9 Cluster: Protein kinase domain containing protei... 135 4e-30
UniRef50_P50528 Cluster: Serine/threonine-protein kinase plo1; n... 135 4e-30
UniRef50_Q62074 Cluster: Protein kinase C iota type; n=26; Eumet... 135 4e-30
UniRef50_P41743 Cluster: Protein kinase C iota type; n=97; Bilat... 135 4e-30
UniRef50_P32562 Cluster: Cell cycle serine/threonine-protein kin... 135 4e-30
UniRef50_UPI00015B4C4D Cluster: PREDICTED: similar to p90 riboso... 134 5e-30
UniRef50_UPI00006CC8B4 Cluster: Protein kinase domain containing... 134 5e-30
UniRef50_Q8MYF1 Cluster: Similar to Dictyostelium discoideum (Sl... 134 5e-30
UniRef50_Q6PLK2 Cluster: Protein kinase B-like protein; n=4; Pla... 134 5e-30
UniRef50_O96997 Cluster: Protein kinase C; n=2; Tetractinomorpha... 134 5e-30
UniRef50_A2FIJ5 Cluster: AGC family protein kinase; n=1; Trichom... 134 5e-30
UniRef50_A0E004 Cluster: Chromosome undetermined scaffold_70, wh... 134 5e-30
UniRef50_Q9URY1 Cluster: Serine/threonine-protein kinase ppk16; ... 134 5e-30
UniRef50_UPI0000DA3F90 Cluster: PREDICTED: similar to serine/thr... 134 7e-30
UniRef50_UPI000069FC64 Cluster: Serine/threonine-protein kinase ... 134 7e-30
UniRef50_A2FCK2 Cluster: CAMK family protein kinase; n=1; Tricho... 134 7e-30
UniRef50_A0DXN2 Cluster: Chromosome undetermined scaffold_69, wh... 134 7e-30
UniRef50_Q6C6T2 Cluster: Similar to sp|P34244 Saccharomyces cere... 134 7e-30
UniRef50_Q6V8K6 Cluster: Gliding motility related CaM kinase; n=... 134 9e-30
UniRef50_Q22UZ4 Cluster: Protein kinase domain containing protei... 134 9e-30
UniRef50_A7SRL3 Cluster: Predicted protein; n=2; Nematostella ve... 134 9e-30
UniRef50_A5K4P1 Cluster: Asparagine-rich protein, putative; n=1;... 134 9e-30
UniRef50_A2EE66 Cluster: AGC family protein kinase; n=1; Trichom... 134 9e-30
UniRef50_A0DGC5 Cluster: Chromosome undetermined scaffold_5, who... 134 9e-30
UniRef50_A0D0Y6 Cluster: Chromosome undetermined scaffold_33, wh... 134 9e-30
UniRef50_A0CWQ7 Cluster: Chromosome undetermined scaffold_3, who... 134 9e-30
UniRef50_Q8SWT6 Cluster: RE56868p; n=4; Drosophila melanogaster|... 133 1e-29
UniRef50_Q24DD1 Cluster: Protein kinase domain containing protei... 133 1e-29
UniRef50_A7RVB0 Cluster: Predicted protein; n=1; Nematostella ve... 133 1e-29
UniRef50_A2ERR6 Cluster: CAMK family protein kinase; n=1; Tricho... 133 1e-29
UniRef50_A2EIG6 Cluster: CAMK family protein kinase; n=1; Tricho... 133 1e-29
UniRef50_Q10292 Cluster: Meiosis-specific serine/threonine-prote... 133 1e-29
UniRef50_P23647 Cluster: Serine/threonine-protein kinase fused; ... 133 1e-29
UniRef50_UPI0000E48F10 Cluster: PREDICTED: similar to salt induc... 133 2e-29
UniRef50_Q90ZY5 Cluster: Protein kinase Chk2; n=4; Danio rerio|R... 133 2e-29
UniRef50_Q4RPX2 Cluster: Chromosome 12 SCAF15007, whole genome s... 133 2e-29
UniRef50_Q5KQF5 Cluster: Putative uncharacterized protein OSJNBa... 133 2e-29
UniRef50_Q76P07 Cluster: Similar to Dictyostelium discoideum (Sl... 133 2e-29
UniRef50_Q22NG7 Cluster: Protein kinase domain containing protei... 133 2e-29
UniRef50_A0E864 Cluster: Chromosome undetermined scaffold_82, wh... 133 2e-29
UniRef50_A0D753 Cluster: Chromosome undetermined scaffold_4, who... 133 2e-29
UniRef50_A0D0M2 Cluster: Chromosome undetermined scaffold_33, wh... 133 2e-29
UniRef50_Q9QYZ3 Cluster: Putative uncharacterized protein Smok; ... 132 2e-29
UniRef50_Q9M269 Cluster: Serine/threonine-protein kinase-like pr... 132 2e-29
UniRef50_A2FA80 Cluster: CAMK family protein kinase; n=2; Tricho... 132 2e-29
UniRef50_A2ET81 Cluster: CAMK family protein kinase; n=1; Tricho... 132 2e-29
UniRef50_A0DTL3 Cluster: Chromosome undetermined scaffold_63, wh... 132 2e-29
UniRef50_A0D805 Cluster: Chromosome undetermined scaffold_40, wh... 132 2e-29
UniRef50_UPI00015B57A5 Cluster: PREDICTED: similar to CG10261-PE... 132 3e-29
UniRef50_UPI000150A707 Cluster: Protein kinase domain containing... 132 3e-29
UniRef50_UPI000049947C Cluster: protein kinase; n=1; Entamoeba h... 132 3e-29
UniRef50_A2F0I9 Cluster: AGC family protein kinase; n=1; Trichom... 132 3e-29
UniRef50_A2E8A4 Cluster: AGC family protein kinase; n=1; Trichom... 132 3e-29
UniRef50_A0BR89 Cluster: Chromosome undetermined scaffold_122, w... 132 3e-29
UniRef50_UPI000069FC63 Cluster: Serine/threonine-protein kinase ... 132 4e-29
UniRef50_Q4SPC4 Cluster: Chromosome undetermined SCAF14539, whol... 132 4e-29
UniRef50_Q3UT86 Cluster: 2 cells egg cDNA, RIKEN full-length enr... 132 4e-29
UniRef50_Q54D55 Cluster: Autophagy protein 1; n=2; Dictyostelium... 132 4e-29
UniRef50_Q4XNV1 Cluster: Rac-beta serine/threonine protein kinas... 132 4e-29
UniRef50_Q22MG9 Cluster: Protein kinase domain containing protei... 132 4e-29
UniRef50_A2G3H5 Cluster: CAMK family protein kinase; n=1; Tricho... 132 4e-29
UniRef50_A2E8U1 Cluster: AGC family protein kinase; n=1; Trichom... 132 4e-29
UniRef50_A0CDF8 Cluster: Chromosome undetermined scaffold_17, wh... 132 4e-29
UniRef50_Q7TSC3 Cluster: Serine/threonine-protein kinase Nek5; n... 132 4e-29
UniRef50_UPI00006CD5AE Cluster: Protein kinase domain containing... 131 5e-29
UniRef50_Q229U9 Cluster: Protein kinase domain containing protei... 131 5e-29
UniRef50_O61225 Cluster: Serine/Threonine protein kinase; n=1; S... 131 5e-29
UniRef50_A2ECT2 Cluster: AGC family protein kinase; n=3; Trichom... 131 5e-29
UniRef50_A2ECN9 Cluster: CAMK family protein kinase; n=1; Tricho... 131 5e-29
UniRef50_A0E6L8 Cluster: Chromosome undetermined scaffold_8, who... 131 5e-29
UniRef50_A0DH53 Cluster: Chromosome undetermined scaffold_50, wh... 131 5e-29
UniRef50_A0CWP3 Cluster: Chromosome undetermined scaffold_3, who... 131 5e-29
UniRef50_A0CNT4 Cluster: Chromosome undetermined scaffold_22, wh... 131 5e-29
UniRef50_UPI000155ED1B Cluster: PREDICTED: similar to serine/thr... 131 7e-29
UniRef50_UPI0000D5696F Cluster: PREDICTED: similar to hormonally... 131 7e-29
UniRef50_A2GM08 Cluster: CAMK family protein kinase; n=2; Tricho... 131 7e-29
UniRef50_A2E224 Cluster: AGC family protein kinase; n=1; Trichom... 131 7e-29
UniRef50_A0CMB4 Cluster: Chromosome undetermined scaffold_21, wh... 131 7e-29
UniRef50_Q6CKE4 Cluster: Similar to sgd|S0006071 Saccharomyces c... 131 7e-29
UniRef50_A7EIW0 Cluster: Putative uncharacterized protein; n=1; ... 131 7e-29
UniRef50_UPI00006A1D6C Cluster: Serine/threonine-protein kinase ... 130 9e-29
UniRef50_Q3B7Y1 Cluster: EG635895 protein; n=11; Mus musculus|Re... 130 9e-29
UniRef50_Q00RV4 Cluster: Protein Kinase; n=2; Ostreococcus|Rep: ... 130 9e-29
UniRef50_A2F9P2 Cluster: CAMK family protein kinase; n=1; Tricho... 130 9e-29
UniRef50_A2EEZ5 Cluster: AGC family protein kinase; n=2; Trichom... 130 9e-29
UniRef50_A2E1Q5 Cluster: CAMK family protein kinase; n=1; Tricho... 130 9e-29
UniRef50_A0DU50 Cluster: Chromosome undetermined scaffold_64, wh... 130 9e-29
UniRef50_Q75C00 Cluster: ACR119Wp; n=1; Eremothecium gossypii|Re... 130 9e-29
UniRef50_O75582 Cluster: Ribosomal protein S6 kinase alpha-5; n=... 130 9e-29
UniRef50_UPI0000499714 Cluster: protein kinase; n=3; Entamoeba h... 130 1e-28
UniRef50_Q4RL54 Cluster: Chromosome 12 SCAF15023, whole genome s... 130 1e-28
UniRef50_Q57VI9 Cluster: Protein kinase, putative; n=3; Trypanos... 130 1e-28
UniRef50_A2G3R6 Cluster: AGC family protein kinase; n=3; Trichom... 130 1e-28
UniRef50_A2EB76 Cluster: CAMK family protein kinase; n=1; Tricho... 130 1e-28
UniRef50_Q6P3R8 Cluster: Serine/threonine-protein kinase Nek5; n... 130 1e-28
UniRef50_Q8C050 Cluster: Ribosomal protein S6 kinase alpha-5; n=... 130 1e-28
UniRef50_Q16566 Cluster: Calcium/calmodulin-dependent protein ki... 130 1e-28
UniRef50_UPI000150A89D Cluster: Protein kinase domain containing... 130 2e-28
UniRef50_A7PXV1 Cluster: Chromosome chr15 scaffold_37, whole gen... 130 2e-28
UniRef50_Q9BMY6 Cluster: CAMP-dependent protein kinase catalytic... 130 2e-28
UniRef50_Q238Z8 Cluster: Protein kinase domain containing protei... 130 2e-28
UniRef50_Q22UA7 Cluster: Protein kinase domain containing protei... 130 2e-28
UniRef50_Q16QY2 Cluster: Ribosomal protein S6 kinase, 90kD, poly... 130 2e-28
UniRef50_A2F4Q4 Cluster: AGC family protein kinase; n=1; Trichom... 130 2e-28
UniRef50_A0EEW8 Cluster: Chromosome undetermined scaffold_92, wh... 130 2e-28
UniRef50_A7TL28 Cluster: Putative uncharacterized protein; n=1; ... 130 2e-28
UniRef50_A7TKP7 Cluster: Putative uncharacterized protein; n=1; ... 130 2e-28
UniRef50_O96017 Cluster: Serine/threonine-protein kinase Chk2; n... 130 2e-28
UniRef50_UPI0000D9C1EE Cluster: PREDICTED: similar to calcium/ca... 129 2e-28
UniRef50_UPI00006CC2DF Cluster: Protein kinase domain containing... 129 2e-28
UniRef50_UPI00006CB7CC Cluster: Protein kinase domain containing... 129 2e-28
UniRef50_Q245J7 Cluster: Protein kinase domain containing protei... 129 2e-28
UniRef50_A2DWP1 Cluster: CAMK family protein kinase; n=3; Tricho... 129 2e-28
UniRef50_A2DIQ7 Cluster: STE family protein kinase; n=1; Trichom... 129 2e-28
UniRef50_A0DYF2 Cluster: Chromosome undetermined scaffold_7, who... 129 2e-28
UniRef50_A0CCI3 Cluster: Chromosome undetermined scaffold_167, w... 129 2e-28
UniRef50_Q6CB57 Cluster: Similar to KLLA0D07348g Kluyveromyces l... 129 2e-28
UniRef50_P54644 Cluster: RAC family serine/threonine-protein kin... 129 2e-28
UniRef50_O61661 Cluster: Serine/threonine-protein kinase grp; n=... 129 2e-28
UniRef50_UPI00015B5A6C Cluster: PREDICTED: hypothetical protein;... 129 3e-28
UniRef50_UPI0001552EAC Cluster: PREDICTED: hypothetical protein;... 129 3e-28
UniRef50_A2EB67 Cluster: CAMK family protein kinase; n=1; Tricho... 129 3e-28
UniRef50_A2DW97 Cluster: CAMK family protein kinase; n=2; Tricho... 129 3e-28
UniRef50_A0EG18 Cluster: Chromosome undetermined scaffold_94, wh... 129 3e-28
UniRef50_Q5AAN6 Cluster: Likely protein kinase; n=1; Candida alb... 129 3e-28
UniRef50_A7TKN7 Cluster: Putative uncharacterized protein; n=1; ... 129 3e-28
UniRef50_A5DV85 Cluster: Serine/threonine-protein kinase SCH9; n... 129 3e-28
UniRef50_UPI0000E7FBCB Cluster: PREDICTED: similar to NIMA (neve... 128 3e-28
UniRef50_Q016K3 Cluster: Snf1 related kinase 1; n=1; Ostreococcu... 128 3e-28
>UniRef50_UPI0000DB7284 Cluster: PREDICTED: similar to CG14305-PA,
isoform A; n=2; Endopterygota|Rep: PREDICTED: similar to
CG14305-PA, isoform A - Apis mellifera
Length = 370
Score = 436 bits (1075), Expect = e-121
Identities = 200/313 (63%), Positives = 247/313 (78%), Gaps = 1/313 (0%)
Query: 1 MTDLKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHK-STLACKIIETAKA 59
MT L T SEE L +GYK K +GEGAYAKVYL EY + D K STLACK+I+T A
Sbjct: 1 MTSLSQTSSEEAVLFARGYKFLKKLGEGAYAKVYLAEYKPESDPEKNSTLACKVIDTGVA 60
Query: 60 PKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVS 119
PKDFV KFLPRE+D+LV+LNHPH++HVHSIFQR+TKYYIFMRY ENGDLL +ILKNG V+
Sbjct: 61 PKDFVRKFLPRELDILVKLNHPHVVHVHSIFQRRTKYYIFMRYAENGDLLEFILKNGAVA 120
Query: 120 ENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPV 179
E QARVW RQLALGLQYLHE+EIAHRD+KCENVLLT+N NVKL+DFGF+R+ +++ + V
Sbjct: 121 EGQARVWFRQLALGLQYLHEMEIAHRDMKCENVLLTSNLNVKLADFGFARYVIDNRGKRV 180
Query: 180 LSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMG 239
+S+TYCGS+SYAAPEILR PY PK DLWSLGV+L+++LNKSMPFDDT +++LYEQQ
Sbjct: 181 MSDTYCGSLSYAAPEILRASPYNPKIADLWSLGVILYILLNKSMPFDDTDIKRLYEQQTN 240
Query: 240 KKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAA 299
+K++FRS++A LS + K +V LLEPD R V++SEWIAMD RL L E AA
Sbjct: 241 RKWKFRSKIAETLSDQVKKLVARLLEPDVSKRWKMDQVINSEWIAMDPRLLILTPAEQAA 300
Query: 300 LKRAKEDRRKLSD 312
L A ++++K +
Sbjct: 301 LNNAIQEKKKFEE 313
Score = 387 bits (952), Expect = e-106
Identities = 176/303 (58%), Positives = 232/303 (76%), Gaps = 2/303 (0%)
Query: 331 ESAF-RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVH 389
E A+ +VYLAEY+ S +K S LACKVIDT AP+DFV+KFLPRE+++L+KL+HPH+VH
Sbjct: 27 EGAYAKVYLAEYKPESDPEKNSTLACKVIDTGVAPKDFVRKFLPRELDILVKLNHPHVVH 86
Query: 390 THSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHR 449
HSIFQRR KY+IFMRY E GDLLEF+L+ GAV E QAR+W RQLAL +QY+HE+EIAHR
Sbjct: 87 VHSIFQRRTKYYIFMRYAENGDLLEFILKNGAVAEGQARVWFRQLALGLQYLHEMEIAHR 146
Query: 450 DIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKP 509
D+KCENVLLT+N NVKL+DFGFAR +D + + S+T+CGSLSY APEIL+ +PY PK
Sbjct: 147 DMKCENVLLTSNLNVKLADFGFARYVIDNRGKRVMSDTYCGSLSYAAPEILRASPYNPKI 206
Query: 510 TDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLE 569
D+WSLG+++Y++LN++MPF+D IK+L++ Q N+ WKFRS+ +T+SD K+L+ +LE
Sbjct: 207 ADLWSLGVILYILLNKSMPFDDTDIKRLYEQQTNRKWKFRSKIAETLSDQVKKLVARLLE 266
Query: 570 PNHQNRLKIYDIVNSEWIAMDSRLLEWTPQETLAYKKAREEKNKLHKTVETVELPGSSKT 629
P+ R K+ ++NSEWIAMD RLL TP E A A +EK K + +V+ P K
Sbjct: 267 PDVSKRWKMDQVINSEWIAMDPRLLILTPAEQAALNNAIQEKKKFEEKF-SVKDPKLFKV 325
Query: 630 EHK 632
E K
Sbjct: 326 EEK 328
>UniRef50_Q17IS8 Cluster: Testis-specific serine/threonine kinase
22c; n=2; Culicidae|Rep: Testis-specific
serine/threonine kinase 22c - Aedes aegypti (Yellowfever
mosquito)
Length = 370
Score = 314 bits (772), Expect = 4e-84
Identities = 149/296 (50%), Positives = 205/296 (69%), Gaps = 2/296 (0%)
Query: 9 SEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68
S + + T GY+ +GEG ++KVYLTEY+ K+ S LACK+I+TA F KFL
Sbjct: 13 SAQEHIKTLGYRFIARLGEGTFSKVYLTEYTHKDASTSEKLACKLIDTAACSPKFKKKFL 72
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTR 128
PRE+ +L+R+ HPH+I V ++ + +K +IFMRY E GDLL++IL +G + ENQ R+W R
Sbjct: 73 PRELAILLRIRHPHIIRVQAMMKCHSKIFIFMRYAEMGDLLTFILAHGPIGENQTRIWGR 132
Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
+AL LQYLHEL IAHRD+KCEN+L+T+NFNVKLSDFGF+R + D LS TYCGS
Sbjct: 133 HMALALQYLHELGIAHRDLKCENILITSNFNVKLSDFGFARH-IMKDGAAELSSTYCGSF 191
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
YAAPEIL+G+PY + +D+W+ GV+L+VMLNKSMPF R + +YE QM +K++FRSRV
Sbjct: 192 DYAAPEILKGQPYDARASDMWAYGVLLYVMLNKSMPFKG-RTKVVYEAQMDRKWQFRSRV 250
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAK 304
LS + K +V +LLEP+P +R++ L W + ++ L E AL A+
Sbjct: 251 RHKLSSQVKLLVGNLLEPNPIIRYTVEETLAYGWYTENPKMRALRPDELHALTEAR 306
Score = 267 bits (655), Expect = 5e-70
Identities = 128/276 (46%), Positives = 187/276 (67%), Gaps = 7/276 (2%)
Query: 335 RVYLAEY--RNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHS 392
+VYL EY ++AS ++KL ACK+IDT+ F KKFLPRE+ +L+++ HPH++ +
Sbjct: 36 KVYLTEYTHKDASTSEKL---ACKLIDTAACSPKFKKKFLPRELAILLRIRHPHIIRVQA 92
Query: 393 IFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIK 452
+ + K FIFMRY E GDLL F+L G + E+Q RIW R +ALA+QY+HEL IAHRD+K
Sbjct: 93 MMKCHSKIFIFMRYAEMGDLLTFILAHGPIGENQTRIWGRHMALALQYLHELGIAHRDLK 152
Query: 453 CENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDV 512
CEN+L+T+N NVKLSDFGFAR + E+ S T+CGS Y APEIL+G PY + +D+
Sbjct: 153 CENILITSNFNVKLSDFGFARHIMKDGAAEL-SSTYCGSFDYAAPEILKGQPYDARASDM 211
Query: 513 WSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNH 572
W+ G+++YVMLN++MPF+ + K +++AQ+++ W+FRSR +S K L+G +LEPN
Sbjct: 212 WAYGVLLYVMLNKSMPFKGR-TKVVYEAQMDRKWQFRSRVRHKLSSQVKLLVGNLLEPNP 270
Query: 573 QNRLKIYDIVNSEWIAMDSRLLEWTPQETLAYKKAR 608
R + + + W + ++ P E A +AR
Sbjct: 271 IIRYTVEETLAYGWYTENPKMRALRPDELHALTEAR 306
>UniRef50_Q9VE58 Cluster: CG14305-PA, isoform A; n=5;
Endopterygota|Rep: CG14305-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 302
Score = 303 bits (744), Expect = 9e-81
Identities = 133/280 (47%), Positives = 194/280 (69%), Gaps = 1/280 (0%)
Query: 4 LKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDF 63
L T S+ + L +GY + +GEG+YA V Y+ + H LACKII+ AKAP DF
Sbjct: 13 LGTRSSDVDALAQRGYNVGHKIGEGSYATVITAGYAD-DHGHGVHLACKIIDKAKAPTDF 71
Query: 64 VVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQA 123
V KF PRE+++L +++H ++I +HSI QR K +IFMRY ENGDLLS+I ++G + E Q+
Sbjct: 72 VNKFFPRELEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDLLSHIKRSGPIDEKQS 131
Query: 124 RVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSET 183
++W Q++ L+YLH L+IAHRD+KCEN+LL+ N+KL+DFGF+R+C + + + + SET
Sbjct: 132 KIWFFQMSKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFARYCRDDNGREMKSET 191
Query: 184 YCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYR 243
YCGS +YAAPE++ G+PY PK D WSLGV+LF+M+N MPFDD+ + KL E Q +K+
Sbjct: 192 YCGSAAYAAPEVVCGRPYDPKLADAWSLGVILFIMMNAKMPFDDSNLTKLLEDQRNRKFA 251
Query: 244 FRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
FR ++ +S + K V LLEP+ R + +L+ W+
Sbjct: 252 FRRKLQETISAQAKATVSVLLEPEAHARWNLREILNCAWL 291
Score = 262 bits (643), Expect = 2e-68
Identities = 112/235 (47%), Positives = 164/235 (69%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
LACK+ID + AP DFV KF PRE+E+L K+ H +++ HSI QR K FIFMRY E GDL
Sbjct: 57 LACKIIDKAKAPTDFVNKFFPRELEILTKIDHSNIIQIHSILQRGPKIFIFMRYAENGDL 116
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
L + + G + E Q++IW Q++ A++Y+H L+IAHRD+KCEN+LL+ N+KL+DFGFA
Sbjct: 117 LSHIKRSGPIDEKQSKIWFFQMSKALKYLHNLDIAHRDLKCENILLSKRLNIKLADFGFA 176
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
R C D E++SET+CGS +Y APE++ G PY PK D WSLG+++++M+N MPF+D
Sbjct: 177 RYCRDDNGREMKSETYCGSAAYAAPEVVCGRPYDPKLADAWSLGVILFIMMNAKMPFDDS 236
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
++ +L + Q N+ + FR + +TIS K + ++LEP R + +I+N W+
Sbjct: 237 NLTKLLEDQRNRKFAFRRKLQETISAQAKATVSVLLEPEAHARWNLREILNCAWL 291
>UniRef50_Q17BC5 Cluster: Testis-specific serine/threonine kinase
22c; n=1; Aedes aegypti|Rep: Testis-specific
serine/threonine kinase 22c - Aedes aegypti (Yellowfever
mosquito)
Length = 336
Score = 271 bits (664), Expect = 4e-71
Identities = 126/270 (46%), Positives = 174/270 (64%), Gaps = 3/270 (1%)
Query: 18 GYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVR 77
GY + +G+G+++ V L +Y SK + + TLACK+I+ K ++F+ KF PRE+ VL++
Sbjct: 38 GYHMGIKIGKGSFSSVRLAKYISK-NQNVQTLACKVIDVRKGTEEFIKKFFPRELSVLMK 96
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
+ HP++I +HSI +R+ +IFM Y E GDLL YI KNG + E QA+ W QL LQYL
Sbjct: 97 IRHPNIIKIHSILKRERMVFIFMDYAEGGDLLKYINKNGIIKETQAKRWFAQLVSALQYL 156
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H ++IAHRD+KCEN+L++ V L+DFGF+R C E + S TYCGS +YAAPE++
Sbjct: 157 HSIDIAHRDLKCENILISKKGTVLLADFGFARVCGEENG--TFSNTYCGSAAYAAPEVIL 214
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
GKPY P D+WSLG++LFVMLN +MPFDD ++KL E + + F V LS+ K
Sbjct: 215 GKPYNPMRADVWSLGIILFVMLNAAMPFDDRNLKKLVEDHWSRNFGFDQTVDKQLSVAAK 274
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWIAMDS 287
V LL PDP R + WI DS
Sbjct: 275 RTVFELLNPDPAERVELEQLKGLGWIDEDS 304
Score = 242 bits (593), Expect = 2e-62
Identities = 113/256 (44%), Positives = 168/256 (65%), Gaps = 4/256 (1%)
Query: 336 VYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQ 395
V LA+Y SKN + LACKVID +F+KKF PRE+ +L+K+ HP+++ HSI +
Sbjct: 53 VRLAKY--ISKNQNVQTLACKVIDVRKGTEEFIKKFFPRELSVLMKIRHPNIIKIHSILK 110
Query: 396 RRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCEN 455
R FIFM Y E GDLL+++ + G ++E QA+ W QL A+QY+H ++IAHRD+KCEN
Sbjct: 111 RERMVFIFMDYAEGGDLLKYINKNGIIKETQAKRWFAQLVSALQYLHSIDIAHRDLKCEN 170
Query: 456 VLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSL 515
+L++ V L+DFGFAR+C ++ N S T+CGS +Y APE++ G PY P DVWSL
Sbjct: 171 ILISKKGTVLLADFGFARVCGEE--NGTFSNTYCGSAAYAAPEVILGKPYNPMRADVWSL 228
Query: 516 GIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNR 575
GI+++VMLN AMPF+D+++K+L + ++N+ F +S KR + +L P+ R
Sbjct: 229 GIILFVMLNAAMPFDDRNLKKLVEDHWSRNFGFDQTVDKQLSVAAKRTVFELLNPDPAER 288
Query: 576 LKIYDIVNSEWIAMDS 591
+++ + WI DS
Sbjct: 289 VELEQLKGLGWIDEDS 304
>UniRef50_Q9BXA7 Cluster: Testis-specific serine/threonine-protein
kinase 1; n=29; Mammalia|Rep: Testis-specific
serine/threonine-protein kinase 1 - Homo sapiens (Human)
Length = 367
Score = 235 bits (576), Expect = 2e-60
Identities = 120/277 (43%), Positives = 177/277 (63%), Gaps = 8/277 (2%)
Query: 14 LLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREID 73
L +GY L +GEG+YAKV S+ + K +A KII+ KAP DF+ KFLPREI+
Sbjct: 7 LKRRGYLLGINLGEGSYAKVK----SAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIE 62
Query: 74 VLVRLNHPHLIHVHSIFQRKT-KYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLAL 132
+L LNH +I + IF+ K YI M GDLL I G + E++AR QL+L
Sbjct: 63 ILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSL 122
Query: 133 GLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDN-QPVLSETYCGSMSYA 191
++Y H+L++ HRD+KC+N+LL +FN+KLSDF FS+ C+ D+ + LS+T+CGS +YA
Sbjct: 123 AIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYA 182
Query: 192 APEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASI 251
APE+L+G PY PK D+WSLGV+L++M+ SMP+DD+ ++K+ Q K++R +
Sbjct: 183 APEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQ--KEHRVNFPRSKH 240
Query: 252 LSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSR 288
L+ ECK ++ H+L+PD R +L W+ +R
Sbjct: 241 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKAR 277
Score = 221 bits (539), Expect = 6e-56
Identities = 116/277 (41%), Positives = 179/277 (64%), Gaps = 10/277 (3%)
Query: 319 KRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEM 378
KR+G +L E ++ + Y S+ K ++ A K+ID AP DF++KFLPREIE+
Sbjct: 8 KRRGYLLGINLGEGSYAKVKSAY---SERLKFNV-AIKIIDRKKAPADFLEKFLPREIEI 63
Query: 379 LIKLSHPHLVHTHSIFQRRY-KYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALA 437
L L+H ++ T+ IF+ + K +I M +GDLLE + RGA+ ED+AR QL+LA
Sbjct: 64 LAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLA 123
Query: 438 IQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCV-DKKLNEIRSETFCGSLSYTA 496
I+Y H+L++ HRD+KC+N+LL + N+KLSDF F++ C+ D S+TFCGS +Y A
Sbjct: 124 IKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAA 183
Query: 497 PEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKF-RSRYIDT 555
PE+LQG PY PK D+WSLG+++Y+M+ +MP++D +IK++ + Q F RS++
Sbjct: 184 PEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH--- 240
Query: 556 ISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSR 592
++ CK LI ML+P+ RL I +I++ W+ +R
Sbjct: 241 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQPKAR 277
>UniRef50_UPI000058436B Cluster: PREDICTED: similar to
Testis-specific serine kinase 1; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Testis-specific
serine kinase 1 - Strongylocentrotus purpuratus
Length = 432
Score = 230 bits (562), Expect = 1e-58
Identities = 120/317 (37%), Positives = 180/317 (56%), Gaps = 10/317 (3%)
Query: 2 TDLKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPK 61
T ++ +EE L KGY L +GEG+YA VY + S+ ++ A KII KAPK
Sbjct: 21 TSVRRVINEEVMLNKKGYTLGLMLGEGSYAAVYSCQLSN----NRGKCAIKIINRKKAPK 76
Query: 62 DFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSEN 121
DF+ KFLPREI +L ++ H +++ IF TK Y+ + +GD+L YI ++E
Sbjct: 77 DFLEKFLPREIKILSKVQHRNIVKCFEIFDTGTKVYMVLELAGHGDMLEYIKLRRSLTEE 136
Query: 122 QARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLS 181
+AR + RQ+ G+ YLH L HRD+KCEN+LL A+ +K+SDFGF+R+ D LS
Sbjct: 137 KARAFFRQMVDGIAYLHSLNAVHRDLKCENILLDASNTIKISDFGFARYMEPKD----LS 192
Query: 182 ETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKK 241
+TYCGS +YAAPEIL+G Y K D+WSLG++L++M+ +MPFDD+ ++++ + QM ++
Sbjct: 193 KTYCGSAAYAAPEILKGNMYNGKAYDVWSLGIILYIMVCGTMPFDDSNIKRMIKDQMDQR 252
Query: 242 YRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALK 301
F R L+L K +V +L+P R ++L+ W+ A
Sbjct: 253 LCFTKR--KELTLLFKDIVLAILQPSAERRLKVNDILNHPWMQDGCNFKQTPPSSQAGTS 310
Query: 302 RAKEDRRKLSDVHKHPP 318
R+ HPP
Sbjct: 311 RSSNASSNRRSPPAHPP 327
Score = 203 bits (495), Expect = 1e-50
Identities = 106/267 (39%), Positives = 164/267 (61%), Gaps = 8/267 (2%)
Query: 337 YLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQR 396
Y A Y N++ A K+I+ AP+DF++KFLPREI++L K+ H ++V IF
Sbjct: 49 YAAVYSCQLSNNR-GKCAIKIINRKKAPKDFLEKFLPREIKILSKVQHRNIVKCFEIFDT 107
Query: 397 RYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENV 456
K ++ + GD+LE++ R ++ E++AR + RQ+ I Y+H L HRD+KCEN+
Sbjct: 108 GTKVYMVLELAGHGDMLEYIKLRRSLTEEKARAFFRQMVDGIAYLHSLNAVHRDLKCENI 167
Query: 457 LLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLG 516
LL A+ +K+SDFGFAR K L S+T+CGS +Y APEIL+G Y K DVWSLG
Sbjct: 168 LLDASNTIKISDFGFARYMEPKDL----SKTYCGSAAYAAPEILKGNMYNGKAYDVWSLG 223
Query: 517 IVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRL 576
I++Y+M+ MPF+D +IK++ + Q+++ F R T+ K ++ +L+P+ + RL
Sbjct: 224 IILYIMVCGTMPFDDSNIKRMIKDQMDQRLCFTKRKELTLL--FKDIVLAILQPSAERRL 281
Query: 577 KIYDIVNSEWIAMDSRLLEWTPQETLA 603
K+ DI+N W+ D + TP + A
Sbjct: 282 KVNDILNHPWM-QDGCNFKQTPPSSQA 307
>UniRef50_Q172E2 Cluster: Testis-specific serine/threonine kinase
22c; n=2; Culicidae|Rep: Testis-specific
serine/threonine kinase 22c - Aedes aegypti (Yellowfever
mosquito)
Length = 305
Score = 222 bits (543), Expect = 2e-56
Identities = 115/272 (42%), Positives = 170/272 (62%), Gaps = 5/272 (1%)
Query: 14 LLTKGYKLTKFVGEGAYAKVYLTEY--SSKEDSHKSTLACKIIETAKAPKDFVVKFLPRE 71
L +GY + + +GEG+Y+KVY +EY S ++ ACKII K+ ++ +FLPRE
Sbjct: 33 LSERGYLIGQSIGEGSYSKVYYSEYRKSGQQQHFPERRACKIINRNKSSMEYS-QFLPRE 91
Query: 72 IDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLA 131
I ++ L+HP+++ V+S+F+ IFM Y GDLL I +G +SE++AR+ RQLA
Sbjct: 92 IKTMIALSHPNIVSVYSVFEFGPYVCIFMDYCRCGDLLQRIQSHGKLSESKARLLFRQLA 151
Query: 132 LGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYA 191
+Q++H HRDIKCENVLL + +VKLSDF F++ C + LS T+CGS +YA
Sbjct: 152 SAVQHMHSRGFCHRDIKCENVLLCSPSHVKLSDFTFAKKCPCEEASQKLSATFCGSAAYA 211
Query: 192 APEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASI 251
APEIL+G PY PK D+WSLG VLF+M+ +MPFD+ + + E+Q K+Y + V
Sbjct: 212 APEILKGIPYHPKRYDMWSLGCVLFIMVTGTMPFDERNIPETIERQERKQYFYPDGVKPN 271
Query: 252 LSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
++ ++ L+EPD R S V+D W+
Sbjct: 272 PTI--IELIDSLIEPDVNARASIDQVVDCAWL 301
Score = 201 bits (490), Expect = 5e-50
Identities = 114/292 (39%), Positives = 170/292 (58%), Gaps = 10/292 (3%)
Query: 299 ALKRAKEDRRKLSDVHKHPPKRQGDILEGPTRESAFRVYLAEYRNASKNDKL-SILACKV 357
AL E RK +V K +R I + S +VY +EYR + + ACK+
Sbjct: 17 ALSSPNEWNRK--EVKKQLSERGYLIGQSIGEGSYSKVYYSEYRKSGQQQHFPERRACKI 74
Query: 358 IDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVL 417
I+ + + ++ +FLPREI+ +I LSHP++V +S+F+ IFM Y GDLL+ +
Sbjct: 75 INRNKSSMEY-SQFLPREIKTMIALSHPNIVSVYSVFEFGPYVCIFMDYCRCGDLLQRIQ 133
Query: 418 QRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVD 477
G + E +AR+ RQLA A+Q+MH HRDIKCENVLL + +VKLSDF FA+ C
Sbjct: 134 SHGKLSESKARLLFRQLASAVQHMHSRGFCHRDIKCENVLLCSPSHVKLSDFTFAKKCPC 193
Query: 478 KKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQL 537
++ ++ S TFCGS +Y APEIL+G PY PK D+WSLG V+++M+ MPF++++I +
Sbjct: 194 EEASQKLSATFCGSAAYAAPEILKGIPYHPKRYDMWSLGCVLFIMVTGTMPFDERNIPET 253
Query: 538 HQAQINKNWKFRSRYIDTISDN--CKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ Q K + Y D + N LI ++EP+ R I +V+ W+
Sbjct: 254 IERQERKQY----FYPDGVKPNPTIIELIDSLIEPDVNARASIDQVVDCAWL 301
>UniRef50_UPI0000D56A9A Cluster: PREDICTED: similar to CG9222-PA;
n=2; Endopterygota|Rep: PREDICTED: similar to CG9222-PA
- Tribolium castaneum
Length = 340
Score = 217 bits (529), Expect = 1e-54
Identities = 112/258 (43%), Positives = 156/258 (60%), Gaps = 8/258 (3%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP 69
++ L + GY L K +G G+YA V + + H +A KI+ AP D++ KFLP
Sbjct: 28 KQTVLESHGYILGKTIGSGSYATVRMAH----SERHNMNVAVKIVSKFSAPADYLKKFLP 83
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
REI+V+ L HP+LI + + YI M Y ENG LL I K+ + E ++R W RQ
Sbjct: 84 REIEVVKGLKHPNLIRFLQAIETTHRVYIIMEYAENGSLLEIIRKDSYIDEIRSRKWFRQ 143
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDN-QPVLSETYCGSM 188
L + Y HE + HRDIKCEN+LL + +KLSDFGF+R ++ N Q LSET+CGS
Sbjct: 144 LVDAVDYCHERGVVHRDIKCENLLLNTEYEIKLSDFGFARGHMKIKNGQAPLSETFCGSY 203
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
+YA+PEIL+G PY P+ +D+WS+GVVLF M+ +PFDDT R L +Q+ K F
Sbjct: 204 AYASPEILKGIPYQPQFSDIWSMGVVLFAMVYGRLPFDDTNYRDLV-KQVTNKVVFPKEP 262
Query: 249 ASILSLECKTVVKHLLEP 266
+SL CK ++ +L P
Sbjct: 263 K--VSLMCKALINKILAP 278
Score = 188 bits (457), Expect = 5e-46
Identities = 95/235 (40%), Positives = 142/235 (60%), Gaps = 5/235 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++ +AP D++KKFLPREIE++ L HP+L+ + ++ +I M Y E G L
Sbjct: 63 VAVKIVSKFSAPADYLKKFLPREIEVVKGLKHPNLIRFLQAIETTHRVYIIMEYAENGSL 122
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
LE + + + E ++R W RQL A+ Y HE + HRDIKCEN+LL +KLSDFGFA
Sbjct: 123 LEIIRKDSYIDEIRSRKWFRQLVDAVDYCHERGVVHRDIKCENLLLNTEYEIKLSDFGFA 182
Query: 473 RMCVDKKLNEI-RSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
R + K + SETFCGS +Y +PEIL+G PY P+ +D+WS+G+V++ M+ +PF+D
Sbjct: 183 RGHMKIKNGQAPLSETFCGSYAYASPEILKGIPYQPQFSDIWSMGVVLFAMVYGRLPFDD 242
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+ + L + Q+ F +S CK LI +L P + R++I I W
Sbjct: 243 TNYRDLVK-QVTNKVVFPKE--PKVSLMCKALINKILAP-LKARIRIPGIKTDPW 293
>UniRef50_Q96PN8 Cluster: Testis-specific serine/threonine-protein
kinase 3; n=15; Amniota|Rep: Testis-specific
serine/threonine-protein kinase 3 - Homo sapiens (Human)
Length = 268
Score = 212 bits (518), Expect = 2e-53
Identities = 113/275 (41%), Positives = 175/275 (63%), Gaps = 11/275 (4%)
Query: 11 ENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR 70
E+ LL+ GY+L K +GEG Y+KV E SK+ H+ +A K+I+ P++F+ +FLPR
Sbjct: 2 EDFLLSNGYQLGKTIGEGTYSKV--KEAFSKK--HQRKVAIKVIDKMGGPEEFIQRFLPR 57
Query: 71 EIDVLVRLNHPHLIHVHSIFQRKT-KYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
E+ ++ L+H ++I V+ + + K + M E GD+ +L G + E++A+ RQ
Sbjct: 58 ELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQ 117
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
+ ++Y H +AHRD+KCEN LL FN+KL+DFGF++ +S + LS+T+CGS +
Sbjct: 118 MVEAIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRE--LSQTFCGSTA 174
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
YAAPE+L+G P+ K D+WS+GVVL+VML S+PFDDT + K+ QQ K F + ++
Sbjct: 175 YAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQ-KGVSFPTHLS 233
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIA 284
+S +C+ ++K LLEPD LR S V W+A
Sbjct: 234 --ISADCQDLLKRLLEPDMILRPSIEEVSWHPWLA 266
Score = 173 bits (420), Expect = 2e-41
Identities = 96/238 (40%), Positives = 147/238 (61%), Gaps = 9/238 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRY-KYFIFMRYMERGD 411
+A KVID P +F+++FLPRE++++ L H +++ + + + K + M E GD
Sbjct: 36 VAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGD 95
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
+ + VL G + E +A+ RQ+ AI+Y H +AHRD+KCEN LL N+KL+DFGF
Sbjct: 96 VFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQGF-NLKLTDFGF 154
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
A++ + K E+ S+TFCGS +Y APE+LQG P+ K DVWS+G+V+YVML ++PF+D
Sbjct: 155 AKV-LPKSHREL-SQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDD 212
Query: 532 KHI-KQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
I K L Q Q K F + +IS +C+ L+ +LEP+ R I ++ W+A
Sbjct: 213 TDIPKMLWQQQ--KGVSFPTHL--SISADCQDLLKRLLEPDMILRPSIEEVSWHPWLA 266
>UniRef50_UPI0000584939 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 313
Score = 211 bits (516), Expect = 4e-53
Identities = 105/257 (40%), Positives = 160/257 (62%), Gaps = 9/257 (3%)
Query: 12 NTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPRE 71
+ L + G+ + + VG G+YA V YS+K HK +A K++ KAP+D+++KFLPRE
Sbjct: 16 SVLESHGFNVQETVGHGSYAAVKCA-YSTK---HKCKVAIKVVSKKKAPEDYLIKFLPRE 71
Query: 72 IDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLA 131
I V+ L HP+LI + ++ Y+ M +NGDLL +I NG +E Q +W QL
Sbjct: 72 IQVVKILKHPNLICFLQSIETTSRVYLIMELADNGDLLDFIKANGAGTEEQTGLWFHQLV 131
Query: 132 LGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVE--SDNQPVLSETYCGSMS 189
G+ Y H L + HRD+KCEN+LL + +K++DFGF+R ++ + +LSETYCGS +
Sbjct: 132 DGMDYCHNLGVVHRDLKCENLLLNKHNMLKITDFGFARSKMKPPEPGRTILSETYCGSYA 191
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
YA PEILRG PYCP D+WS+GV+L+ ML +P+DDT K+ Q+ + F + +
Sbjct: 192 YAPPEILRGIPYCPMLGDIWSMGVILYTMLYGRLPYDDTN-HKVLLNQVQRPPGFPT--S 248
Query: 250 SILSLECKTVVKHLLEP 266
++ +CK ++ +L P
Sbjct: 249 QVVHSDCKDLMCRILSP 265
Score = 174 bits (424), Expect = 5e-42
Identities = 87/236 (36%), Positives = 140/236 (59%), Gaps = 6/236 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KV+ AP D++ KFLPREI+++ L HP+L+ + + ++ M + GDL
Sbjct: 49 VAIKVVSKKKAPEDYLIKFLPREIQVVKILKHPNLICFLQSIETTSRVYLIMELADNGDL 108
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
L+F+ GA E+Q +W QL + Y H L + HRD+KCEN+LL + +K++DFGFA
Sbjct: 109 LDFIKANGAGTEEQTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKHNMLKITDFGFA 168
Query: 473 R--MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
R M + I SET+CGS +Y PEIL+G PY P D+WS+G+++Y ML +P++
Sbjct: 169 RSKMKPPEPGRTILSETYCGSYAYAPPEILRGIPYCPMLGDIWSMGVILYTMLYGRLPYD 228
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
D + K L Q+ + F + + + +CK L+ +L P + R+ + +I ++ W
Sbjct: 229 DTNHKVLLN-QVQRPPGFPTSQV--VHSDCKDLMCRILSP-AKRRINMEEIQHNAW 280
>UniRef50_A7SRN4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 368
Score = 209 bits (511), Expect = 2e-52
Identities = 113/308 (36%), Positives = 174/308 (56%), Gaps = 10/308 (3%)
Query: 18 GYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVR 77
GY L +G+G+YA V YS K K +A KI+ KAP D++ KFLPREI V+
Sbjct: 60 GYALGDTLGKGSYA-VVKAAYSRKL---KKQVAVKIVTKKKAPDDYLTKFLPREIQVMKH 115
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
LNH +++ +H + ++ YI + +NGDLL YI NG + EN+AR++ QL ++YL
Sbjct: 116 LNHSNVVSLHEAIETSSRIYIILDLADNGDLLEYIRSNGAIPENEARLFYHQLVDAVEYL 175
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSR--FCVESDNQPVLSETYCGSMSYAAPEI 195
H + HRD+KCEN+LL + + +SDFGF+R + + LS+T+CGS +YA PEI
Sbjct: 176 HNKGVVHRDLKCENILLNRDNRILISDFGFARTQHVMADTGKRRLSQTFCGSYAYAPPEI 235
Query: 196 LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLE 255
LRG Y D+WSLGVVL+ M++ S+PFDDT ++ L E Q+ + F R +S E
Sbjct: 236 LRGIAYDGTLADIWSLGVVLYTMVSASLPFDDTNLKVLLE-QVSRDVVFSRR--KKISDE 292
Query: 256 CKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKEDRRKLSDVHK 315
K +V+ +L D R ++ W + ++ + ++ + +++ D +
Sbjct: 293 VKDLVRRMLVADVKTRIDLASIRRHPWF-VGTKFSDAAKIDEVPQHEISKSKQEAQDSGQ 351
Query: 316 HPPKRQGD 323
K GD
Sbjct: 352 SSGKSSGD 359
Score = 182 bits (444), Expect = 2e-44
Identities = 92/261 (35%), Positives = 154/261 (59%), Gaps = 11/261 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++ AP D++ KFLPREI+++ L+H ++V H + + +I + + GDL
Sbjct: 87 VAVKIVTKKKAPDDYLTKFLPREIQVMKHLNHSNVVSLHEAIETSSRIYIILDLADNGDL 146
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
LE++ GA+ E++AR++ QL A++Y+H + HRD+KCEN+LL + + +SDFGFA
Sbjct: 147 LEYIRSNGAIPENEARLFYHQLVDAVEYLHNKGVVHRDLKCENILLNRDNRILISDFGFA 206
Query: 473 R---MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF 529
R + D + S+TFCGS +Y PEIL+G Y D+WSLG+V+Y M++ ++PF
Sbjct: 207 RTQHVMADTGKRRL-SQTFCGSYAYAPPEILRGIAYDGTLADIWSLGVVLYTMVSASLPF 265
Query: 530 EDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA- 588
+D ++K L + Q++++ F R ISD K L+ ML + + R+ + I W
Sbjct: 266 DDTNLKVLLE-QVSRDVVFSRR--KKISDEVKDLVRRMLVADVKTRIDLASIRRHPWFVG 322
Query: 589 ---MDSRLLEWTPQETLAYKK 606
D+ ++ PQ ++ K
Sbjct: 323 TKFSDAAKIDEVPQHEISKSK 343
>UniRef50_A7RKT6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 261
Score = 209 bits (510), Expect = 2e-52
Identities = 107/270 (39%), Positives = 166/270 (61%), Gaps = 13/270 (4%)
Query: 13 TLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREI 72
TL GY + + +GEGA+AKV L +K H +A KII+ KAPKD++ KFLPREI
Sbjct: 2 TLELHGYTVMRNLGEGAFAKVKL----AKSKKHNCHVAIKIIDKRKAPKDYIYKFLPREI 57
Query: 73 DVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLAL 132
V+ +LNHP++I ++ + +TK Y+ + E GDLL YI KN + E +ARV Q
Sbjct: 58 RVMHKLNHPNVIQLYEAIETETKVYLILELAEGGDLLEYINKNALLPEERARVIFCQFVA 117
Query: 133 GLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAA 192
+ Y H+ + HRD+KCEN+LL AN +K++DFGF+ C + ++ + +T+CGS +Y +
Sbjct: 118 TMAYCHKERVVHRDLKCENLLLDANGRLKITDFGFA--C--NTHKTNILQTFCGSYAYCS 173
Query: 193 PEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASIL 252
PEILRG Y + +D+WS+GVVL+ ++ +PF D +R + ++ +K RF +
Sbjct: 174 PEILRGDLYDGQASDIWSMGVVLYALVCARLPFGDDDLRAIMNRE-PRKLRFSKKT---- 228
Query: 253 SLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
S EC+ +++ +L D R +A +L W
Sbjct: 229 SKECRELIRKMLALDEKKRPTAEELLHEPW 258
Score = 171 bits (417), Expect = 4e-41
Identities = 82/234 (35%), Positives = 139/234 (59%), Gaps = 9/234 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID AP+D++ KFLPREI ++ KL+HP+++ + + K ++ + E GDL
Sbjct: 34 VAIKIIDKRKAPKDYIYKFLPREIRVMHKLNHPNVIQLYEAIETETKVYLILELAEGGDL 93
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
LE++ + + E++AR+ Q + Y H+ + HRD+KCEN+LL AN +K++DFGFA
Sbjct: 94 LEYINKNALLPEERARVIFCQFVATMAYCHKERVVHRDLKCENLLLDANGRLKITDFGFA 153
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
C K N + +TFCGS +Y +PEIL+G Y + +D+WS+G+V+Y ++ +PF D
Sbjct: 154 --CNTHKTNIL--QTFCGSYAYCSPEILRGDLYDGQASDIWSMGVVLYALVCARLPFGDD 209
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
++ + + K R+ S C+ LI ML + + R ++++ W
Sbjct: 210 DLRAIMNREPRK-----LRFSKKTSKECRELIRKMLALDEKKRPTAEELLHEPW 258
>UniRef50_Q9BXA6 Cluster: Testis-specific serine/threonine-protein
kinase 6; n=14; Euteleostomi|Rep: Testis-specific
serine/threonine-protein kinase 6 - Homo sapiens (Human)
Length = 273
Score = 204 bits (499), Expect = 4e-51
Identities = 117/277 (42%), Positives = 166/277 (59%), Gaps = 13/277 (4%)
Query: 9 SEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68
S + L GYKL + +GEG+Y+KV + +SK+ +K T+A K+++ +AP DFV KFL
Sbjct: 2 SGDKLLSELGYKLGRTIGEGSYSKVKVA--TSKK--YKGTVAIKVVDRRRAPPDFVNKFL 57
Query: 69 PREIDVLVRLNHPHLIHVHSIFQR-KTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127
PRE+ +L + HPH++HV + K YI M DLL + +NG + QAR
Sbjct: 58 PRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLF 116
Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFN-VKLSDFGFSRFCVESDNQPVLSETYCG 186
Q+A ++YLH+ + HRD+KCENVLL+ + VKL+DFGF R ++ P LS TYCG
Sbjct: 117 AQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR---QAHGYPDLSTTYCG 173
Query: 187 SMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRS 246
S +YA+PE+L G PY PK D+WS+GVVL+VM+ MPFDD+ + L +Q K
Sbjct: 174 SAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQ---KRGVLY 230
Query: 247 RVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
LS CK ++ LL+ P R SA V + W+
Sbjct: 231 PEGLELSERCKALIAELLQFSPSARPSAGQVARNCWL 267
Score = 166 bits (404), Expect = 1e-39
Identities = 94/237 (39%), Positives = 138/237 (58%), Gaps = 9/237 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQR-RYKYFIFMRYMERGD 411
+A KV+D AP DFV KFLPRE+ +L + HPH+VH + K +I M D
Sbjct: 38 VAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-D 96
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQN-VKLSDFG 470
LL+ V + G + QAR Q+A A++Y+H+ + HRD+KCENVLL+ ++ VKL+DFG
Sbjct: 97 LLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFG 156
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
F R ++ S T+CGS +Y +PE+L G PY PK DVWS+G+V+YVM+ MPF+
Sbjct: 157 FGRQA--HGYPDL-STTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFD 213
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
D I L + Q K ++ +S+ CK LI +L+ + R + + W+
Sbjct: 214 DSDIAGLPRRQ--KRGVLYPEGLE-LSERCKALIAELLQFSPSARPSAGQVARNCWL 267
>UniRef50_A7SGS0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 297
Score = 204 bits (498), Expect = 6e-51
Identities = 107/258 (41%), Positives = 161/258 (62%), Gaps = 8/258 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID AP DF+ KFLPRE+ ++ +L H H++ +F+ R K ++ M RGDL
Sbjct: 44 VAVKIIDKKRAPSDFINKFLPREMVVIKRLRHKHIIQVLDLFEVREKVYVIMELATRGDL 103
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
LE++ RG V+E +A+ QL A++Y H+ + HRD+KCENVLL NVKL+DFGF+
Sbjct: 104 LEYIRYRGCVRERKAKKVFSQLLQAVKYCHQQGVIHRDLKCENVLLDIGDNVKLTDFGFS 163
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
++ K+L +TFCGS +Y A EILQGT Y + D+WSLGI++Y M+ MPF+D
Sbjct: 164 KLNPRKEL----CKTFCGSAAYAAIEILQGTEYDGEKADIWSLGIILYTMVTGRMPFDDA 219
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSR 592
++ L + QI + +FR + +S+ C+ LI ML N++ R+ I +I WI D R
Sbjct: 220 NMTTLLR-QIKRGVEFR-KPKQMVSEECRDLIRCMLTHNYEYRITIPEIEAHRWIISDLR 277
Query: 593 L-LEWTPQETL-AYKKAR 608
T ++T+ ++K AR
Sbjct: 278 EGSSSTSEQTIESFKSAR 295
Score = 203 bits (495), Expect = 1e-50
Identities = 112/281 (39%), Positives = 164/281 (58%), Gaps = 12/281 (4%)
Query: 10 EENTLLTKGYKLTKF--VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKF 67
E L +GY+ +GEG YAKV YS++ +H +A KII+ +AP DF+ KF
Sbjct: 7 EARVLRDRGYQFVDNGRLGEGTYAKVKCA-YSTQLANH---VAVKIIDKKRAPSDFINKF 62
Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127
LPRE+ V+ RL H H+I V +F+ + K Y+ M GDLL YI GCV E +A+
Sbjct: 63 LPREMVVIKRLRHKHIIQVLDLFEVREKVYVIMELATRGDLLEYIRYRGCVRERKAKKVF 122
Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187
QL ++Y H+ + HRD+KCENVLL NVKL+DFGFS+ + + L +T+CGS
Sbjct: 123 SQLLQAVKYCHQQGVIHRDLKCENVLLDIGDNVKLTDFGFSKL----NPRKELCKTFCGS 178
Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSR 247
+YAA EIL+G Y + D+WSLG++L+ M+ MPFDD M L +Q+ + FR +
Sbjct: 179 AAYAAIEILQGTEYDGEKADIWSLGIILYTMVTGRMPFDDANMTTLL-RQIKRGVEFR-K 236
Query: 248 VASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSR 288
++S EC+ +++ +L + R + + WI D R
Sbjct: 237 PKQMVSEECRDLIRCMLTHNYEYRITIPEIEAHRWIISDLR 277
>UniRef50_UPI000058436C Cluster: PREDICTED: similar to
Testis-specific serine kinase 1; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Testis-specific
serine kinase 1 - Strongylocentrotus purpuratus
Length = 314
Score = 204 bits (497), Expect = 8e-51
Identities = 102/279 (36%), Positives = 172/279 (61%), Gaps = 13/279 (4%)
Query: 9 SEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68
++ +L+ G+ L +G G+Y+KV + + + + +A KII+ +AP+D+ FL
Sbjct: 39 NDGTVMLSHGFCLAHKLGSGSYSKVRMAVHKTT----RKRVAVKIIDRRRAPRDYQDHFL 94
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYI--LKNGCVSENQARVW 126
PRE+ V+ +L HP+++ + F++ K Y+ + E+GD+L YI + G V E AR W
Sbjct: 95 PRELAVIRQLQHPNVLRTYEWFEQNQKVYMVLELAESGDVLEYIRTVTKGAVPEVLARKW 154
Query: 127 TRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCG 186
+ Q L Y+H +++ HRD+KCEN+LL N+KL+DFGF V S + LS+T+CG
Sbjct: 155 SLQTGRALLYMHGMDVVHRDVKCENLLLDRCNNIKLTDFGF----VRSVGKGSLSKTFCG 210
Query: 187 SMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF-DDTR-MRKLYEQQMGKKYRF 244
S +YAAPEI+R PYCP +D+W+LGVV+++++ MPF DD + ++K+ QQ +
Sbjct: 211 SAAYAAPEIIRSVPYCPLKSDVWALGVVIYILVVGCMPFGDDVKNIKKILHQQYSGAHFD 270
Query: 245 RSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
S+ ++ EC+ +++ +L P R + V++SEW+
Sbjct: 271 ASKNTAVRD-ECRDLIRSMLTISPKARLTLGEVMESEWL 308
Score = 194 bits (473), Expect = 6e-48
Identities = 97/240 (40%), Positives = 151/240 (62%), Gaps = 11/240 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID APRD+ FLPRE+ ++ +L HP+++ T+ F++ K ++ + E GD+
Sbjct: 75 VAVKIIDRRRAPRDYQDHFLPRELAVIRQLQHPNVLRTYEWFEQNQKVYMVLELAESGDV 134
Query: 413 LEFV--LQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFG 470
LE++ + +GAV E AR W+ Q A+ YMH +++ HRD+KCEN+LL N+KL+DFG
Sbjct: 135 LEYIRTVTKGAVPEVLARKWSLQTGRALLYMHGMDVVHRDVKCENLLLDRCNNIKLTDFG 194
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
F R L S+TFCGS +Y APEI++ PY P +DVW+LG+V+Y+++ MPF
Sbjct: 195 FVRSVGKGSL----SKTFCGSAAYAAPEIIRSVPYCPLKSDVWALGVVIYILVVGCMPFG 250
Query: 531 D--KHIKQ-LHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
D K+IK+ LHQ + F + + D C+ LI ML + + RL + +++ SEW+
Sbjct: 251 DDVKNIKKILHQQYSGAH--FDASKNTAVRDECRDLIRSMLTISPKARLTLGEVMESEWL 308
>UniRef50_Q6SA08 Cluster: Testis-specific serine/threonine-protein
kinase 4; n=30; Eutheria|Rep: Testis-specific
serine/threonine-protein kinase 4 - Homo sapiens (Human)
Length = 328
Score = 196 bits (477), Expect = 2e-48
Identities = 110/292 (37%), Positives = 164/292 (56%), Gaps = 24/292 (8%)
Query: 6 TTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVV 65
TT + + + GY++ K +G G+Y VY Y+ + K +A KII KA D++
Sbjct: 12 TTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQ----KVMVAVKIISKKKASDDYLN 67
Query: 66 KFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARV 125
KFLPREI V+ L H +LI+ + + ++ YI + + GD+L +I + G SE A
Sbjct: 68 KFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGK 127
Query: 126 WTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPV------ 179
W QL LG+ YLH I HRD+K EN+LL NVK+SDFGF++ + NQPV
Sbjct: 128 WFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSY 185
Query: 180 --------LSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMR 231
LS+TYCGS +YA PEILRG PY P +D WS+GV+L+ ++ +PFDDT ++
Sbjct: 186 RQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLK 245
Query: 232 KLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
KL + K+ F + +S ECK ++ +L R + +++ W+
Sbjct: 246 KLLRETQ-KEVTFPAN--HTISQECKNLILQMLR-QATKRATILDIIKDSWV 293
Score = 172 bits (418), Expect = 3e-41
Identities = 97/280 (34%), Positives = 156/280 (55%), Gaps = 22/280 (7%)
Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
++A K+I A D++ KFLPREI+++ L H +L++ + + + +I + + GD
Sbjct: 50 MVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGD 109
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
+LE++ + GA E A W QL L I Y+H I HRD+K EN+LL +NVK+SDFGF
Sbjct: 110 VLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGF 169
Query: 472 ARMCVD----------KKLN--EIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVV 519
A+M +++N S+T+CGS +Y PEIL+G PY P +D WS+G+++
Sbjct: 170 AKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVIL 229
Query: 520 YVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIY 579
Y ++ +PF+D ++K+L + + K F + + TIS CK LI ML R I
Sbjct: 230 YTLVVAHLPFDDTNLKKLLR-ETQKEVTFPANH--TISQECKNLILQMLR-QATKRATIL 285
Query: 580 DIVNSEWIAMDSRLLEWTPQETLAYKKAREEKNKLHKTVE 619
DI+ W+ L++ P++ + E +LH T +
Sbjct: 286 DIIKDSWV------LKFQPEQPTHEIRLLEAMCQLHNTTK 319
>UniRef50_UPI00015B608A Cluster: PREDICTED: similar to AT03158p;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
AT03158p - Nasonia vitripennis
Length = 347
Score = 194 bits (473), Expect = 6e-48
Identities = 106/278 (38%), Positives = 158/278 (56%), Gaps = 9/278 (3%)
Query: 9 SEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68
S L GY L K +G G +A V + +K + H +A KI+ +AP + KFL
Sbjct: 27 SRLTVLENHGYTLGKTIGVGTFATVKI----AKSERHGYQVAVKIVSKFQAPSANLNKFL 82
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTR 128
P EI+V+ L HPHLI + + YI M + ENG L + ++ + E ++R W R
Sbjct: 83 PSEIEVVKGLRHPHLIRFLQAIETSHRIYIIMEFAENGSLFDILRRDKFIDEIRSRRWYR 142
Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPV-LSETYCGS 187
QL L Y HE + HRD+KCEN+L+ ++N+KLSDFGF+R ++S N L ET CGS
Sbjct: 143 QLLDALNYCHERGVVHRDVKCENLLMDRHYNLKLSDFGFARGHMKSANGVAPLCETMCGS 202
Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSR 247
+Y++PEILRG PY P+ +D+WS GVVL+ M+ MPFD+ +L +Q+ K F
Sbjct: 203 FAYSSPEILRGIPYQPQLSDIWSSGVVLYTMVFGRMPFDEDNWSRLL-KQVQSKIVFPE- 260
Query: 248 VASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAM 285
+ +S EC+ ++ +L P R + + W+A+
Sbjct: 261 -SPKVSQECRNLILRILVPQRS-RPRICEIQNDVWLAI 296
Score = 174 bits (424), Expect = 5e-42
Identities = 91/263 (34%), Positives = 151/263 (57%), Gaps = 7/263 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++ AP + KFLP EIE++ L HPHL+ + ++ +I M + E G L
Sbjct: 63 VAVKIVSKFQAPSANLNKFLPSEIEVVKGLRHPHLIRFLQAIETSHRIYIIMEFAENGSL 122
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ + + + E ++R W RQL A+ Y HE + HRD+KCEN+L+ + N+KLSDFGFA
Sbjct: 123 FDILRRDKFIDEIRSRRWYRQLLDALNYCHERGVVHRDVKCENLLMDRHYNLKLSDFGFA 182
Query: 473 RMCVDKKLNEIR--SETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
R + K N + ET CGS +Y++PEIL+G PY P+ +D+WS G+V+Y M+ MPF+
Sbjct: 183 RGHM-KSANGVAPLCETMCGSFAYSSPEILRGIPYQPQLSDIWSSGVVLYTMVFGRMPFD 241
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
+ + +L + Q+ F +S C+ LI +L P ++R +I +I N W+A+
Sbjct: 242 EDNWSRLLK-QVQSKIVFPES--PKVSQECRNLILRILVP-QRSRPRICEIQNDVWLAIP 297
Query: 591 SRLLEWTPQETLAYKKAREEKNK 613
+ + + + + + K++
Sbjct: 298 TATAQTSTDDVFLGESSNSAKSQ 320
>UniRef50_UPI000155D3B2 Cluster: PREDICTED: similar to
serine/threonine protein kinase SSTK, partial; n=3;
Amniota|Rep: PREDICTED: similar to serine/threonine
protein kinase SSTK, partial - Ornithorhynchus anatinus
Length = 809
Score = 192 bits (468), Expect = 3e-47
Identities = 108/274 (39%), Positives = 162/274 (59%), Gaps = 15/274 (5%)
Query: 18 GYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVR 77
GY+L K +GEG+Y KV + + + +T+A KII +APKDFV KFLPRE+ VL
Sbjct: 11 GYRLGKTIGEGSYCKVNMGVWGREN----TTVAIKIINLQRAPKDFVDKFLPRELSVLRV 66
Query: 78 LNHPHLIHVHSIFQ-RKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
+ HPH++ V + + K YI M +L + + G + +A+ + QL + Y
Sbjct: 67 IRHPHIVQVLELIEVGSDKIYIVMEAL-GSNLFKVLRRQGYFNCTRAQEFFSQLVSAIHY 125
Query: 137 LHELEIAHRDIKCENVLLTANFN-VKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEI 195
LH ++ HRDIKCEN+LLT + +KL+DF FSR + + LS T+CGS++YA+PE+
Sbjct: 126 LHCQQVVHRDIKCENILLTHDEQCIKLTDFSFSRQVHDFGD---LSTTFCGSVAYASPEV 182
Query: 196 LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKL-YEQQMGKKYRFRSRVASILSL 254
L G PY PK D+WSLGVVL+ M+ MPF D + KL + Q+ G ++ R ++A
Sbjct: 183 LLGIPYDPKKYDMWSLGVVLYAMVTGRMPFSDVAVIKLPHFQKQGVEFPKRPKLAE---- 238
Query: 255 ECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSR 288
CK ++ LL+ P R +A V + W+ +S+
Sbjct: 239 PCKVLINDLLQFTPSARPTAGQVARNSWLCKESQ 272
Score = 157 bits (382), Expect = 7e-37
Identities = 88/242 (36%), Positives = 141/242 (58%), Gaps = 9/242 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQ-RRYKYFIFMRYMERGD 411
+A K+I+ AP+DFV KFLPRE+ +L + HPH+V + + K +I M + +
Sbjct: 38 VAIKIINLQRAPKDFVDKFLPRELSVLRVIRHPHIVQVLELIEVGSDKIYIVMEALG-SN 96
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQN-VKLSDFG 470
L + + ++G +A+ + QL AI Y+H ++ HRDIKCEN+LLT ++ +KL+DF
Sbjct: 97 LFKVLRRQGYFNCTRAQEFFSQLVSAIHYLHCQQVVHRDIKCENILLTHDEQCIKLTDFS 156
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
F+R D ++ S TFCGS++Y +PE+L G PY PK D+WSLG+V+Y M+ MPF
Sbjct: 157 FSRQVHD--FGDL-STTFCGSVAYASPEVLLGIPYDPKKYDMWSLGVVLYAMVTGRMPFS 213
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
D + +L Q + +F R +++ CK LI +L+ R + + W+ +
Sbjct: 214 DVAVIKLPHFQ-KQGVEFPKR--PKLAEPCKVLINDLLQFTPSARPTAGQVARNSWLCKE 270
Query: 591 SR 592
S+
Sbjct: 271 SQ 272
>UniRef50_Q8T4D4 Cluster: AT03158p; n=2; Sophophora|Rep: AT03158p -
Drosophila melanogaster (Fruit fly)
Length = 337
Score = 192 bits (468), Expect = 3e-47
Identities = 104/281 (37%), Positives = 164/281 (58%), Gaps = 10/281 (3%)
Query: 3 DLKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKD 62
D K+ P ++ L G L K +G G YAKV + + + +A KII KAP +
Sbjct: 61 DDKSKP-QKTILEEHGIILGKVIGTGNYAKVKI----GFSEEYGKRVAVKIISKVKAPSE 115
Query: 63 FVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQ 122
+ KFLPREI+ + L+H +LI + + + Y+ M+ ENG LL Y+ + + E Q
Sbjct: 116 YTQKFLPREIEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERKFLDEPQ 175
Query: 123 ARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVE-SDNQPVLS 181
+R +QL ++Y+H + HRDIKCEN+LL N+N+KL DFGF+R SDNQ +LS
Sbjct: 176 SRTLFKQLVSAVEYIHSKGVVHRDIKCENLLLDENWNLKLIDFGFARKDTRTSDNQVILS 235
Query: 182 ETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKK 241
+T+CGS +YA+PEIL+G Y P +D+W+ GVV + M+ +P+D + + L +++ +
Sbjct: 236 KTFCGSYAYASPEILKGVAYDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILL-KRINQS 294
Query: 242 YRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
F ++ S ECK ++ H+L P +R++ V + W
Sbjct: 295 LVFPKSPSA--SSECKHMIMHILAP-VKIRYNIPQVKEDPW 332
Score = 165 bits (401), Expect = 3e-39
Identities = 84/219 (38%), Positives = 133/219 (60%), Gaps = 4/219 (1%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I AP ++ +KFLPREIE + L H +L+ + + ++ ++ M+ E G L
Sbjct: 102 VAVKIISKVKAPSEYTQKFLPREIEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTL 161
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
L++V +R + E Q+R +QL A++Y+H + HRDIKCEN+LL N N+KL DFGFA
Sbjct: 162 LDYVRERKFLDEPQSRTLFKQLVSAVEYIHSKGVVHRDIKCENLLLDENWNLKLIDFGFA 221
Query: 473 RMCVDKKLNE-IRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
R N+ I S+TFCGS +Y +PEIL+G Y P +D+W+ G+V Y M+ +P++
Sbjct: 222 RKDTRTSDNQVILSKTFCGSYAYASPEILKGVAYDPFMSDIWACGVVCYAMVFGRLPYDG 281
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEP 570
++ L + +IN++ F + S CK +I +L P
Sbjct: 282 SNVHILLK-RINQSLVFPKS--PSASSECKHMIMHILAP 317
>UniRef50_Q7Q893 Cluster: ENSANGP00000015772; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000015772 - Anopheles gambiae
str. PEST
Length = 268
Score = 188 bits (457), Expect = 5e-46
Identities = 104/254 (40%), Positives = 150/254 (59%), Gaps = 7/254 (2%)
Query: 13 TLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREI 72
TL T GY + +G+G YA V Y +K K T+A KI+ A + F+ K LPRE+
Sbjct: 2 TLATHGYIVGDVIGQGTYA-VVKKAYWTK---FKRTVAIKIMSKTNAGETFLQKCLPREL 57
Query: 73 DVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLAL 132
D + L H ++IH + + + + YI MRY E+G LLS I K G + E +AR + RQL
Sbjct: 58 DAIRNLRHENIIHYYEVIETTMRVYISMRYAEHGTLLSLIRKQGHLPEVRARRYYRQLLA 117
Query: 133 GLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAA 192
L+Y+H AHRDIK EN++L N +KL DFGF+ +D PVLS+T+CGS +YA+
Sbjct: 118 ALEYIHTAGYAHRDIKLENMVLDGNDRLKLIDFGFACRARVAD-APVLSKTFCGSHAYAS 176
Query: 193 PEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASIL 252
PE+LR KPY P D+W+ GVVL+ +L +PF + + L Q++ + F S V
Sbjct: 177 PELLRFKPYDPVHADIWASGVVLYSLLYGKLPFSNEKQVNLLLQKINRGVIFPSNVTVTR 236
Query: 253 SLECKTVVKHLLEP 266
++C ++K L P
Sbjct: 237 EVQC--LLKQLFLP 248
Score = 151 bits (365), Expect = 8e-35
Identities = 76/209 (36%), Positives = 123/209 (58%), Gaps = 3/209 (1%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++ + A F++K LPRE++ + L H +++H + + + + +I MRY E G L
Sbjct: 34 VAIKIMSKTNAGETFLQKCLPRELDAIRNLRHENIIHYYEVIETTMRVYISMRYAEHGTL 93
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
L + ++G + E +AR + RQL A++Y+H AHRDIK EN++L N +KL DFGFA
Sbjct: 94 LSLIRKQGHLPEVRARRYYRQLLAALEYIHTAGYAHRDIKLENMVLDGNDRLKLIDFGFA 153
Query: 473 RMCVDKKLN-EIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
C + + + S+TFCGS +Y +PE+L+ PY P D+W+ G+V+Y +L +PF +
Sbjct: 154 --CRARVADAPVLSKTFCGSHAYASPELLRFKPYDPVHADIWASGVVLYSLLYGKLPFSN 211
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNC 560
+ L +IN+ F S T C
Sbjct: 212 EKQVNLLLQKINRGVIFPSNVTVTREVQC 240
>UniRef50_UPI0000DB7653 Cluster: PREDICTED: similar to CG15072-PA;
n=2; Apocrita|Rep: PREDICTED: similar to CG15072-PA -
Apis mellifera
Length = 901
Score = 184 bits (447), Expect = 9e-45
Identities = 98/276 (35%), Positives = 159/276 (57%), Gaps = 14/276 (5%)
Query: 12 NTLLTKGY-KLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR 70
N L+ GY +L K +G+G +A V + + KS +A KII+ K ++ + K R
Sbjct: 18 NKLIRVGYYELEKTIGKGNFAVVKMATHVVT----KSKVAIKIIDKTKLNEENLAKIF-R 72
Query: 71 EIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQL 130
E+ ++ RL HPH+I ++ + + + Y+ Y G++ ++++NG + E +AR RQ+
Sbjct: 73 EVHIMKRLRHPHIIRLYQVMETEKMIYLVTEYAPGGEIFDHLVRNGRMPEPEARRIFRQI 132
Query: 131 ALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSY 190
L ++YLH+ + HRD+K EN+LL A+ N+KL+DFGFS V T+CGS Y
Sbjct: 133 VLAVRYLHQQRVVHRDLKAENLLLDADNNIKLADFGFS----NEYTPGVPLNTWCGSPPY 188
Query: 191 AAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVAS 250
AAPEI GK Y D+WSLGVVL+V++ ++PFD M+ L + K+ R+
Sbjct: 189 AAPEIFEGKHYDGPRADVWSLGVVLYVLVCGALPFDGPTMQLLRSVVISGKF----RIPF 244
Query: 251 ILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMD 286
+S EC+ +++H+L +P R S + +L W+ D
Sbjct: 245 FMSAECEKLIRHMLVVEPERRLSISQILAHSWMGGD 280
Score = 153 bits (371), Expect = 1e-35
Identities = 80/240 (33%), Positives = 137/240 (57%), Gaps = 9/240 (3%)
Query: 351 SILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERG 410
S +A K+ID + + + K RE+ ++ +L HPH++ + + + ++ Y G
Sbjct: 50 SKVAIKIIDKTKLNEENLAKIF-REVHIMKRLRHPHIIRLYQVMETEKMIYLVTEYAPGG 108
Query: 411 DLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFG 470
++ + +++ G + E +AR RQ+ LA++Y+H+ + HRD+K EN+LL A+ N+KL+DFG
Sbjct: 109 EIFDHLVRNGRMPEPEARRIFRQIVLAVRYLHQQRVVHRDLKAENLLLDADNNIKLADFG 168
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
F+ ++ + T+CGS Y APEI +G Y DVWSLG+V+YV++ A+PF+
Sbjct: 169 FS----NEYTPGVPLNTWCGSPPYAAPEIFEGKHYDGPRADVWSLGVVLYVLVCGALPFD 224
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
++ L I + KFR + +S C++LI ML + RL I I+ W+ D
Sbjct: 225 GPTMQLLRSVVI--SGKFRIPFF--MSAECEKLIRHMLVVEPERRLSISQILAHSWMGGD 280
>UniRef50_A7RR18 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 270
Score = 180 bits (439), Expect = 8e-44
Identities = 101/273 (36%), Positives = 159/273 (58%), Gaps = 8/273 (2%)
Query: 14 LLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREID 73
L +GY+L +G+GAYA+V YS+K + +A KIIE AK KF+ RE++
Sbjct: 3 LCRQGYELGSILGKGAYAEVK-EAYSNKLGRN---VAVKIIEKAKLSSKSFNKFMRREVE 58
Query: 74 VLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALG 133
L +++H ++I + + + ++Y+ + +NGDLL + K + EN+AR +++ G
Sbjct: 59 ALRQVDHKYVISLIEVLESSKRFYLVLELAQNGDLLQLLQKKKQLHENEARKIFKKIVKG 118
Query: 134 LQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVL---SETYCGSMSY 190
+ + H IAHRD+K EN+LL+ +SDFGF+R+ S + + S T+CGS +Y
Sbjct: 119 VLHCHRKGIAHRDLKLENILLSRKNEPIISDFGFARYVGGSSDTCMTRPRSNTFCGSYAY 178
Query: 191 AAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVAS 250
AAPEIL+G PY +D+WSLGVVLF M+ PFDD R+L + K+ + + ++
Sbjct: 179 AAPEILQGIPYDATSSDVWSLGVVLFAMVTGRFPFDDQDRRQLLRHTLAGKFSY-PKGSA 237
Query: 251 ILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
LS + K +VK++L D R + V D WI
Sbjct: 238 RLSDQLKELVKNMLTADIKSRLTLEEVYDHPWI 270
Score = 155 bits (375), Expect = 5e-36
Identities = 80/252 (31%), Positives = 140/252 (55%), Gaps = 4/252 (1%)
Query: 339 AEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRY 398
AE + A N +A K+I+ + KF+ RE+E L ++ H +++ + +
Sbjct: 20 AEVKEAYSNKLGRNVAVKIIEKAKLSSKSFNKFMRREVEALRQVDHKYVISLIEVLESSK 79
Query: 399 KYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLL 458
++++ + + GDLL+ + ++ + E++AR +++ + + H IAHRD+K EN+LL
Sbjct: 80 RFYLVLELAQNGDLLQLLQKKKQLHENEARKIFKKIVKGVLHCHRKGIAHRDLKLENILL 139
Query: 459 TANQNVKLSDFGFARM---CVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSL 515
+ +SDFGFAR D + RS TFCGS +Y APEILQG PY +DVWSL
Sbjct: 140 SRKNEPIISDFGFARYVGGSSDTCMTRPRSNTFCGSYAYAAPEILQGIPYDATSSDVWSL 199
Query: 516 GIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNR 575
G+V++ M+ PF+D+ +QL + + + + + +SD K L+ ML + ++R
Sbjct: 200 GVVLFAMVTGRFPFDDQDRRQLLRHTLAGKFSY-PKGSARLSDQLKELVKNMLTADIKSR 258
Query: 576 LKIYDIVNSEWI 587
L + ++ + WI
Sbjct: 259 LTLEEVYDHPWI 270
>UniRef50_Q23128 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 367
Score = 180 bits (437), Expect = 1e-43
Identities = 101/260 (38%), Positives = 154/260 (59%), Gaps = 12/260 (4%)
Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84
+G G Y+KVY + + ++ +A K I+T + D +KFLPRE+ +L +P ++
Sbjct: 100 LGRGKYSKVY----KAFDRNNNRVVAVKAIDTQELTTDVKMKFLPRELSCWRKLKNPFVV 155
Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144
+H+ ++ ++ ++ M Y GDLL Y+ ++G + E +A ++ QL GLQ++H + IAH
Sbjct: 156 GLHAQYEAQSMIFLTMEYGSQGDLLRYVQEHGGIHEQKAGLFMSQLIRGLQFMHSINIAH 215
Query: 145 RDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPK 204
RDIK EN++L N VKLSDFGF R ES LS T+CGS SY+APE+LRG Y P
Sbjct: 216 RDIKLENIILFDNC-VKLSDFGFVRKMDES----ALSSTFCGSKSYSAPELLRGIVYNPF 270
Query: 205 PTDLWSLGVVLFVMLNKSMPFDDTRMRK-LYEQQMGKKYRFRSRVASILSLECKTVVKHL 263
+D+WSLGVV FVM+ MPFD+ + + E Q ++Y V LS C + + +
Sbjct: 271 LSDVWSLGVVGFVMVTNRMPFDEKKPNNVIVELQRNRQYVIPHSV--FLSTSCISSFESM 328
Query: 264 LEPDPGLRHSATNVLDSEWI 283
+ D R ++T+ L WI
Sbjct: 329 MAFDTRNRPTSTDCLALPWI 348
Score = 169 bits (410), Expect = 3e-40
Identities = 94/251 (37%), Positives = 142/251 (56%), Gaps = 7/251 (2%)
Query: 337 YLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQR 396
Y Y+ +N+ ++A K IDT D KFLPRE+ KL +P +V H+ ++
Sbjct: 105 YSKVYKAFDRNNN-RVVAVKAIDTQELTTDVKMKFLPRELSCWRKLKNPFVVGLHAQYEA 163
Query: 397 RYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENV 456
+ F+ M Y +GDLL +V + G + E +A ++ QL +Q+MH + IAHRDIK EN+
Sbjct: 164 QSMIFLTMEYGSQGDLLRYVQEHGGIHEQKAGLFMSQLIRGLQFMHSINIAHRDIKLENI 223
Query: 457 LLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLG 516
+L N VKLSDFGF R + L S TFCGS SY+APE+L+G Y P +DVWSLG
Sbjct: 224 ILFDN-CVKLSDFGFVRKMDESAL----SSTFCGSKSYSAPELLRGIVYNPFLSDVWSLG 278
Query: 517 IVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRL 576
+V +VM+ MPF++K + ++ +N ++ + +S +C M+ + +NR
Sbjct: 279 VVGFVMVTNRMPFDEKKPNNV-IVELQRNRQYVIPHSVFLSTSCISSFESMMAFDTRNRP 337
Query: 577 KIYDIVNSEWI 587
D + WI
Sbjct: 338 TSTDCLALPWI 348
>UniRef50_UPI0000D55D86 Cluster: PREDICTED: similar to SNF1-like
kinase 2; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to SNF1-like kinase 2 - Tribolium castaneum
Length = 831
Score = 178 bits (434), Expect = 3e-43
Identities = 93/277 (33%), Positives = 160/277 (57%), Gaps = 14/277 (5%)
Query: 10 EENTLLTKG-YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68
E T + G Y + + +G+G +A V L +K K+ +A KII+ ++ + K
Sbjct: 6 ERKTAVRVGFYDIERTIGKGNFAVVKL----AKHRITKTEVAIKIIDKSQLDAGNLQKVY 61
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTR 128
RE+D++ RL+HPH+I ++ + + K Y+ Y G++ YI + G ++E+QAR
Sbjct: 62 -REVDIMKRLDHPHIIKLYQVMETKNMIYLVSEYASQGEIFDYIARYGRMTEDQARTKFW 120
Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
Q+ ++Y H I HRD+K EN+LL +N N+K++DFGFS + VLS T+CGS
Sbjct: 121 QILSAVEYCHNRNIVHRDLKAENLLLDSNNNIKIADFGFSNYYTSGG---VLS-TWCGSP 176
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
YAAPE+ GK Y D+WSLGVVL+V++ ++PFD + L ++ + ++ R+
Sbjct: 177 PYAAPEVFEGKKYTGPEIDIWSLGVVLYVLVCGALPFDGCSLPALRDRVLSGRF----RI 232
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAM 285
+S +C+++++ +L +P R+S + + W+ M
Sbjct: 233 PYFMSSDCESLIRKMLVLEPNKRYSISQIKKHRWMQM 269
Score = 151 bits (365), Expect = 8e-35
Identities = 79/239 (33%), Positives = 134/239 (56%), Gaps = 13/239 (5%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID S ++K RE++++ +L HPH++ + + + + ++ Y +G++
Sbjct: 42 VAIKIIDKSQLDAGNLQKVY-REVDIMKRLDHPHIIKLYQVMETKNMIYLVSEYASQGEI 100
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++ + G + EDQAR Q+ A++Y H I HRD+K EN+LL +N N+K++DFGF+
Sbjct: 101 FDYIARYGRMTEDQARTKFWQILSAVEYCHNRNIVHRDLKAENLLLDSNNNIKIADFGFS 160
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ T+CGS Y APE+ +G Y D+WSLG+V+YV++ A+PF+
Sbjct: 161 NYYTSGGV----LSTWCGSPPYAAPEVFEGKKYTGPEIDIWSLGVVLYVLVCGALPFDGC 216
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIG--LMLEPNHQNRLKIYDIVNSEWIAM 589
+ L + + +FR Y +S +C+ LI L+LEPN R I I W+ M
Sbjct: 217 SLPALRDRVL--SGRFRIPYF--MSSDCESLIRKMLVLEPN--KRYSISQIKKHRWMQM 269
>UniRef50_Q17E44 Cluster: Map/microtubule affinity-regulating kinase
2,4; n=2; Culicidae|Rep: Map/microtubule
affinity-regulating kinase 2,4 - Aedes aegypti
(Yellowfever mosquito)
Length = 1026
Score = 178 bits (433), Expect = 4e-43
Identities = 96/286 (33%), Positives = 166/286 (58%), Gaps = 20/286 (6%)
Query: 2 TDLKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEY--SSKEDSHKSTLACKIIETAKA 59
T + P+EE+ + K YKL K +G+G +AKV L ++ +SKE +A KII+ +
Sbjct: 387 TGARWRPAEEH--IGK-YKLLKTIGKGNFAKVKLAKHVPTSKE------VAIKIIDKTQL 437
Query: 60 PKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVS 119
+ K L RE+ ++ L+HP+++ + + + + Y+ M Y G++ Y++ +G +
Sbjct: 438 NASSLQK-LYREVRIMKLLDHPNIVKLFQVIETEKTLYLVMEYASGGEVFDYLVLHGRMK 496
Query: 120 ENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPV 179
E +AR RQ+ +QY H+ I HRD+K EN+LL + N+K++DFGFS
Sbjct: 497 EKEARAKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSEMNIKIADFGFSNQFTPGSK--- 553
Query: 180 LSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMG 239
+T+CGS YAAPE+ +G+ Y D+WSLGV+L+ +++ S+PFD +R+L E+ +
Sbjct: 554 -LDTFCGSPPYAAPELFQGRKYDGPEVDVWSLGVILYTLVSGSLPFDGATLRELRERVLR 612
Query: 240 KKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAM 285
KY R+ +S +C+ ++K L +P R S +++ +W+ M
Sbjct: 613 GKY----RIPFYMSTDCENLLKKFLVLNPAKRASLESIMKDKWMNM 654
Score = 149 bits (362), Expect = 2e-34
Identities = 76/246 (30%), Positives = 136/246 (55%), Gaps = 9/246 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID + ++K L RE+ ++ L HP++V + + ++ M Y G++
Sbjct: 427 VAIKIIDKTQLNASSLQK-LYREVRIMKLLDHPNIVKLFQVIETEKTLYLVMEYASGGEV 485
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++ G ++E +AR RQ+ A+QY H+ I HRD+K EN+LL + N+K++DFGF+
Sbjct: 486 FDYLVLHGRMKEKEARAKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSEMNIKIADFGFS 545
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ +TFCGS Y APE+ QG Y DVWSLG+++Y +++ ++PF+
Sbjct: 546 NQFTPGS----KLDTFCGSPPYAAPELFQGRKYDGPEVDVWSLGVILYTLVSGSLPFDGA 601
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSR 592
+++L + + K+R + +S +C+ L+ L N R + I+ +W+ M
Sbjct: 602 TLRELRERVL--RGKYRIPFY--MSTDCENLLKKFLVLNPAKRASLESIMKDKWMNMGYE 657
Query: 593 LLEWTP 598
E TP
Sbjct: 658 DDELTP 663
>UniRef50_Q16HI1 Cluster: Testis-specific serine/threonine kinase
22c; n=2; Aedes aegypti|Rep: Testis-specific
serine/threonine kinase 22c - Aedes aegypti (Yellowfever
mosquito)
Length = 297
Score = 177 bits (432), Expect = 6e-43
Identities = 90/222 (40%), Positives = 140/222 (63%), Gaps = 9/222 (4%)
Query: 11 ENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR 70
E+ L GY + + +G GA++ V + SK +H +A KII KA KD + KFLPR
Sbjct: 33 ESVLELNGYIVQETIGTGAFSNV--KKAFSKSLNHP--VAVKIISKQKATKDVLDKFLPR 88
Query: 71 EIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQL 130
EI+++ L H +LI H + ++YI M+Y ENG LL I K +SE +++ + QL
Sbjct: 89 EIELVRNLKHANLIRFHECIETTLRFYIVMQYAENGSLLQLIKKEKYLSEERSKSFFTQL 148
Query: 131 ALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVE-----SDNQPVLSETYC 185
++Y+H + + HRDIKCEN++ +F +KL DFGF+R ++ +PVLS+T+C
Sbjct: 149 ISAVEYIHGMGVVHRDIKCENIVFDKSFTLKLIDFGFARGNMQPVLAGGKIKPVLSKTFC 208
Query: 186 GSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDD 227
GS +YA+PEIL+ PY P+ +D+W++GVVL+ M+ +PF +
Sbjct: 209 GSHAYASPEILKSVPYQPQLSDIWAVGVVLYTMVIGRLPFSN 250
Score = 158 bits (384), Expect = 4e-37
Identities = 69/185 (37%), Positives = 118/185 (63%), Gaps = 5/185 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I A +D + KFLPREIE++ L H +L+ H + +++I M+Y E G L
Sbjct: 67 VAVKIISKQKATKDVLDKFLPREIELVRNLKHANLIRFHECIETTLRFYIVMQYAENGSL 126
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
L+ + + + E++++ + QL A++Y+H + + HRDIKCEN++ + +KL DFGFA
Sbjct: 127 LQLIKKEKYLSEERSKSFFTQLISAVEYIHGMGVVHRDIKCENIVFDKSFTLKLIDFGFA 186
Query: 473 R-----MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAM 527
R + K+ + S+TFCGS +Y +PEIL+ PY P+ +D+W++G+V+Y M+ +
Sbjct: 187 RGNMQPVLAGGKIKPVLSKTFCGSHAYASPEILKSVPYQPQLSDIWAVGVVLYTMVIGRL 246
Query: 528 PFEDK 532
PF ++
Sbjct: 247 PFSNE 251
>UniRef50_Q4SL09 Cluster: Chromosome 17 SCAF14563, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 17
SCAF14563, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 885
Score = 176 bits (429), Expect = 1e-42
Identities = 106/354 (29%), Positives = 182/354 (51%), Gaps = 17/354 (4%)
Query: 7 TPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVK 66
T +EE+ + Y+L K +G+G +AKV L + +A KII+ + + K
Sbjct: 87 TSTEEHPHIGN-YRLLKTIGKGNFAKVKLARHVLTGRE----VAVKIIDKTQLNPTSLQK 141
Query: 67 FLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVW 126
RE+ ++ LNHP+++ + + + + Y+ M Y G++ Y++ +G + E +AR
Sbjct: 142 LF-REVRIMKLLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAK 200
Query: 127 TRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFS-RFCVESDNQPVLSETYC 185
RQ+ +QY H+ I HRD+K EN+LL A+ N+K++DFGFS F + S +T+C
Sbjct: 201 FRQIVSAVQYCHQRRIVHRDLKAENLLLDADMNIKIADFGFSNEFTMGSK-----LDTFC 255
Query: 186 GSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFR 245
GS YAAPE+ +GK Y D+WSLGV+L+ +++ S+PFD +++L E+ + KY
Sbjct: 256 GSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKY--- 312
Query: 246 SRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKE 305
R+ +S +C+ ++K LL +P R S ++ W+ + L +
Sbjct: 313 -RIPFYMSTDCENLLKKLLVLNPVKRGSLEQIMKDHWMNVGHEEEELKPYIEPEADFSDS 371
Query: 306 DRRKLSDVHKHPPKRQGDILEGPTRESAFRVYLAEYRNASK-NDKLSILACKVI 358
R +L +P + L + YL R A + + +S +C VI
Sbjct: 372 SRIELMVTMGYPKDEITESLHSQKYDDVMATYLLLGRKAPEVSFSISSPSCHVI 425
Score = 152 bits (368), Expect = 3e-35
Identities = 78/237 (32%), Positives = 137/237 (57%), Gaps = 13/237 (5%)
Query: 353 LACKVID-TSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A K+ID T P K F RE+ ++ L+HP++V + + ++ M Y G+
Sbjct: 124 VAVKIIDKTQLNPTSLQKLF--REVRIMKLLNHPNIVKLFEVIETEKTLYLVMEYASGGE 181
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
+ ++++ G ++E +AR RQ+ A+QY H+ I HRD+K EN+LL A+ N+K++DFGF
Sbjct: 182 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQRRIVHRDLKAENLLLDADMNIKIADFGF 241
Query: 472 A-RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+ + KL +TFCGS Y APE+ QG Y DVWSLG+++Y +++ ++PF+
Sbjct: 242 SNEFTMGSKL-----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD 296
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+++K+L + + K+R + +S +C+ L+ +L N R + I+ W+
Sbjct: 297 GQNLKELRERVL--RGKYRIPFY--MSTDCENLLKKLLVLNPVKRGSLEQIMKDHWM 349
>UniRef50_UPI000065EE71 Cluster: MAP/microtubule affinity-regulating
kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein
kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein
kinase p78) (Ser/Thr protein kinase PAR-1) (Protein
kinase STK10).; n=9; Euteleostomi|Rep: MAP/microtubule
affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C-
associated protein kinase 1) (cTAK1) (C-TAK1)
(Serine/threonine protein kinase p78) (Ser/Thr protein
kinase PAR-1) (Protein kinase STK10). - Takifugu
rubripes
Length = 818
Score = 176 bits (428), Expect = 2e-42
Identities = 90/266 (33%), Positives = 152/266 (57%), Gaps = 15/266 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G+G +AKV L + +A KII+ + + K RE+ ++ L
Sbjct: 52 YRLLKTIGKGNFAKVKLARHVLTGRE----VAVKIIDKTQLNPTSLQKLF-REVRIMKIL 106
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHP+++ + + + + Y+ M Y G++ Y++ +G + E +AR RQ+ +QY H
Sbjct: 107 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQILSAVQYCH 166
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFS-RFCVESDNQPVLSETYCGSMSYAAPEILR 197
+ I HRD+K EN+LL A+ N+K++DFGFS F V +T+CGS YAAPE+ +
Sbjct: 167 QKHIVHRDLKAENLLLDADMNIKIADFGFSNEFSVGGK-----LDTFCGSPPYAAPELFQ 221
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
GK Y D+WSLGV+L+ +++ S+PFD +++L E+ + KY R+ +S +C+
Sbjct: 222 GKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKY----RIPFYMSTDCE 277
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWI 283
++K L +PG R + ++ WI
Sbjct: 278 NLLKRFLVLNPGKRGTLEQIMKDRWI 303
Score = 153 bits (370), Expect = 2e-35
Identities = 83/248 (33%), Positives = 139/248 (56%), Gaps = 13/248 (5%)
Query: 353 LACKVID-TSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A K+ID T P K F RE+ ++ L+HP++V + + ++ M Y G+
Sbjct: 78 VAVKIIDKTQLNPTSLQKLF--REVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGE 135
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
+ ++++ G ++E +AR RQ+ A+QY H+ I HRD+K EN+LL A+ N+K++DFGF
Sbjct: 136 VFDYLVAHGRMKEKEARAKFRQILSAVQYCHQKHIVHRDLKAENLLLDADMNIKIADFGF 195
Query: 472 A-RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+ V KL +TFCGS Y APE+ QG Y DVWSLG+++Y +++ ++PF+
Sbjct: 196 SNEFSVGGKL-----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD 250
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
+++K+L + + K+R + +S +C+ L+ L N R + I+ WI
Sbjct: 251 GQNLKELRERVL--RGKYRIPFY--MSTDCENLLKRFLVLNPGKRGTLEQIMKDRWINTG 306
Query: 591 SRLLEWTP 598
S E P
Sbjct: 307 SEEEELKP 314
>UniRef50_UPI0000E47483 Cluster: PREDICTED: similar to
Testis-specific serine kinase 1; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Testis-specific
serine kinase 1 - Strongylocentrotus purpuratus
Length = 416
Score = 175 bits (427), Expect = 2e-42
Identities = 89/262 (33%), Positives = 148/262 (56%), Gaps = 12/262 (4%)
Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84
+GEG YAKV YS E K +A KI+ ++ F KFLPRE+ ++ + HPH+I
Sbjct: 144 LGEGTYAKVRRA-YSYSE---KCRVAIKIVSRSRLNARFQQKFLPRELKIVRNMRHPHII 199
Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144
+ +F+ ++ M +GDLL Y+ K + +++AR Q+ +++LH + H
Sbjct: 200 ELLEMFESNGVIFLIMELARHGDLLEYVQKKNALRDSEARTVFSQILSAVEHLHFHGVYH 259
Query: 145 RDIKCENVLL---TANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPY 201
RD+KCEN+LL K++DFGF+R E+ T+CGS +YA+PEIL+ PY
Sbjct: 260 RDLKCENILLDWGPTGITAKITDFGFAREWSEAFKP---CSTFCGSAAYASPEILQAIPY 316
Query: 202 CPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVK 261
P D+WSLG++L++M+ MPFDD+ +++ E + + F R ++ +E + +++
Sbjct: 317 DPNWADIWSLGIILYIMVTGRMPFDDSNIKQALEDMLNSRLNFSRR--RLVCIEVQRLLR 374
Query: 262 HLLEPDPGLRHSATNVLDSEWI 283
+L DP R + +S W+
Sbjct: 375 AILTYDPRQRPGVQEIKNSPWM 396
Score = 169 bits (411), Expect = 2e-40
Identities = 88/252 (34%), Positives = 142/252 (56%), Gaps = 8/252 (3%)
Query: 339 AEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRY 398
A+ R A + +A K++ S F +KFLPRE++++ + HPH++ +F+
Sbjct: 150 AKVRRAYSYSEKCRVAIKIVSRSRLNARFQQKFLPRELKIVRNMRHPHIIELLEMFESNG 209
Query: 399 KYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLL 458
F+ M GDLLE+V ++ A+++ +AR Q+ A++++H + HRD+KCEN+LL
Sbjct: 210 VIFLIMELARHGDLLEYVQKKNALRDSEARTVFSQILSAVEHLHFHGVYHRDLKCENILL 269
Query: 459 ---TANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSL 515
K++DFGFAR + TFCGS +Y +PEILQ PY P D+WSL
Sbjct: 270 DWGPTGITAKITDFGFAREWSEAFK---PCSTFCGSAAYASPEILQAIPYDPNWADIWSL 326
Query: 516 GIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNR 575
GI++Y+M+ MPF+D +IKQ + +N F R + I +RL+ +L + + R
Sbjct: 327 GIILYIMVTGRMPFDDSNIKQALEDMLNSRLNFSRRRLVCI--EVQRLLRAILTYDPRQR 384
Query: 576 LKIYDIVNSEWI 587
+ +I NS W+
Sbjct: 385 PGVQEIKNSPWM 396
>UniRef50_Q5DTG3 Cluster: MKIAA4230 protein; n=16; Bilateria|Rep:
MKIAA4230 protein - Mus musculus (Mouse)
Length = 408
Score = 175 bits (425), Expect = 4e-42
Identities = 90/266 (33%), Positives = 152/266 (57%), Gaps = 15/266 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G+G +AKV L + +A KII+ + + K RE+ ++ L
Sbjct: 64 YRLLKTIGKGNFAKVKLARHILTGRE----VAIKIIDKTQLNPTSLQKLF-REVRIMKIL 118
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHP+++ + + + + Y+ M Y G++ Y++ +G + E +AR RQ+ +QY H
Sbjct: 119 NHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 178
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFS-RFCVESDNQPVLSETYCGSMSYAAPEILR 197
+ I HRD+K EN+LL A+ N+K++DFGFS F V S +T+CGS YAAPE+ +
Sbjct: 179 QKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSK-----LDTFCGSPPYAAPELFQ 233
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
GK Y D+WSLGV+L+ +++ S+PFD +++L E+ + KY R+ +S +C+
Sbjct: 234 GKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKY----RIPFYMSTDCE 289
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWI 283
++K L +P R + ++ WI
Sbjct: 290 NLLKRFLVLNPVKRGTLEQIMKDRWI 315
Score = 153 bits (371), Expect = 1e-35
Identities = 80/237 (33%), Positives = 136/237 (57%), Gaps = 13/237 (5%)
Query: 353 LACKVID-TSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A K+ID T P K F RE+ ++ L+HP++V + + ++ M Y G+
Sbjct: 90 VAIKIIDKTQLNPTSLQKLF--REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGE 147
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
+ ++++ G ++E +AR RQ+ A+QY H+ I HRD+K EN+LL A+ N+K++DFGF
Sbjct: 148 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGF 207
Query: 472 A-RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+ V KL +TFCGS Y APE+ QG Y DVWSLG+++Y +++ ++PF+
Sbjct: 208 SNEFTVGSKL-----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD 262
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+++K+L + + K+R + +S +C+ L+ L N R + I+ WI
Sbjct: 263 GQNLKELRERVL--RGKYRIPFY--MSTDCENLLKRFLVLNPVKRGTLEQIMKDRWI 315
>UniRef50_Q9VGP9 Cluster: CG6715-PA; n=7; Sophophora|Rep: CG6715-PA
- Drosophila melanogaster (Fruit fly)
Length = 705
Score = 174 bits (424), Expect = 5e-42
Identities = 93/265 (35%), Positives = 150/265 (56%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
YK+ K +G+G +AKV L + +A K+I+ + K L RE+ ++ L
Sbjct: 98 YKIIKTLGKGNFAKVKLAIHVPTGRE----VAIKVIDKTQLNTSARQK-LYREVKIMKLL 152
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHP+++ + + + + Y+ M Y G+L +++KNG + E ARV RQL +QY H
Sbjct: 153 NHPNIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDARVIFRQLVSAIQYCH 212
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ HRD+K EN+LL + N+K++DFGF D L ET+CGS YAAPE+ G
Sbjct: 213 SKFVVHRDLKAENLLLDQHMNIKIADFGFGN---TFDPNAQL-ETFCGSPPYAAPELFMG 268
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y D WSLGVVL+ +++ S+PFD +++L E+ + KY RV +S++C+
Sbjct: 269 RKYAGPEVDAWSLGVVLYTLVSGSLPFDGGTLKELRERVLRGKY----RVPYYISMDCEN 324
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
+++ L +P R S + V+ +WI
Sbjct: 325 LMRKFLVLNPAKRTSLSAVMSDKWI 349
Score = 151 bits (365), Expect = 8e-35
Identities = 80/235 (34%), Positives = 132/235 (56%), Gaps = 9/235 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KVID T ++ L RE++++ L+HP++V + + ++ M Y RG+L
Sbjct: 124 VAIKVID-KTQLNTSARQKLYREVKIMKLLNHPNIVRLFQVIESERTLYLVMEYASRGEL 182
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ +++ G ++E AR+ RQL AIQY H + HRD+K EN+LL + N+K++DFGF
Sbjct: 183 FDHLVKNGRMRERDARVIFRQLVSAIQYCHSKFVVHRDLKAENLLLDQHMNIKIADFGFG 242
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
D + ETFCGS Y APE+ G Y D WSLG+V+Y +++ ++PF+
Sbjct: 243 N-TFDP---NAQLETFCGSPPYAAPELFMGRKYAGPEVDAWSLGVVLYTLVSGSLPFDGG 298
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+K+L + + K+R Y IS +C+ L+ L N R + +++ +WI
Sbjct: 299 TLKELRERVL--RGKYRVPYY--ISMDCENLMRKFLVLNPAKRTSLSAVMSDKWI 349
>UniRef50_A0E900 Cluster: Chromosome undetermined scaffold_83, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_83,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 662
Score = 174 bits (423), Expect = 7e-42
Identities = 92/265 (34%), Positives = 152/265 (57%), Gaps = 12/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y L K +GEG + +V L +++ + T+A KI+E K ++ + + REI+ L +L
Sbjct: 9 YILGKTIGEGTFGQVRLGQHTITNE----TVAIKILEKDKMKEETDYERISREINCLKKL 64
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP++I ++ I Q Y+ M Y G+L I++N ++E +A + Q+ G+QY+H
Sbjct: 65 RHPNIIQIYEIVQTVNSLYLIMEYAPGGELFDVIIRNQRLNEKEAADYLMQILSGVQYMH 124
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
E + HRD+K EN+LL N +K+ DFG S D Q L +T CGS YAAPE++ G
Sbjct: 125 ENYVMHRDLKPENLLLDENNKIKIVDFGLSN--QFKDGQ--LLKTACGSPCYAAPEMIAG 180
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y PK D WS GV+L+ M+N +PF+D +++Y++ + +Y +S CK
Sbjct: 181 KEYDPKSADTWSCGVILYAMVNGYLPFEDNNQKQMYKKIVYGEY----APPKYMSPLCKD 236
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
+++ +L+ DP R++ ++ WI
Sbjct: 237 LLEKILQVDPLKRYNIHQIVKHYWI 261
Score = 146 bits (354), Expect = 2e-33
Identities = 75/235 (31%), Positives = 127/235 (54%), Gaps = 8/235 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ + + + REI L KL HP+++ + I Q ++ M Y G+L
Sbjct: 35 VAIKILEKDKMKEETDYERISREINCLKKLRHPNIIQIYEIVQTVNSLYLIMEYAPGGEL 94
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ +++ + E +A + Q+ +QYMHE + HRD+K EN+LL N +K+ DFG +
Sbjct: 95 FDVIIRNQRLNEKEAADYLMQILSGVQYMHENYVMHRDLKPENLLLDENNKIKIVDFGLS 154
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
D +L +T CGS Y APE++ G Y PK D WS G+++Y M+N +PFED
Sbjct: 155 NQFKDGQL----LKTACGSPCYAAPEMIAGKEYDPKSADTWSCGVILYAMVNGYLPFEDN 210
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ KQ+++ + + +Y+ + CK L+ +L+ + R I+ IV WI
Sbjct: 211 NQKQMYKKIVYGEYA-PPKYMSPL---CKDLLEKILQVDPLKRYNIHQIVKHYWI 261
>UniRef50_A7QFL3 Cluster: Chromosome chr8 scaffold_88, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr8 scaffold_88, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 435
Score = 173 bits (422), Expect = 9e-42
Identities = 94/270 (34%), Positives = 157/270 (58%), Gaps = 10/270 (3%)
Query: 13 TLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREI 72
++L + Y+L K +G+G +AKV+ ++ +++A KII+ K K +V + REI
Sbjct: 6 SILMQRYELGKLLGQGTFAKVH----HARNLKTGTSVAIKIIDKEKILKVGMVDQIKREI 61
Query: 73 DVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLAL 132
V+ + HP+++ ++ + KTK Y M Y + G+L + + K G + E+ AR + +QL
Sbjct: 62 SVMRLVRHPNVVELYEVMASKTKIYFVMEYAKGGELFNKVAK-GKLKEDVARKYFQQLIS 120
Query: 133 GLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAA 192
+ + H + HRD+K EN+LL N N+K+SDFG S ES +Q L T CG+ +Y A
Sbjct: 121 AVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLSALA-ESKHQDGLLHTTCGTPAYVA 179
Query: 193 PEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASIL 252
PE++ K Y D+WS GVVLFV+L +PF D+ + +LY + +YRF + S
Sbjct: 180 PEVINRKGYDGAKADIWSCGVVLFVLLAGYLPFHDSNLMELYRKIGKAEYRFPNWFPS-- 237
Query: 253 SLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
E + ++ +L+P+P R S T ++++ W
Sbjct: 238 --EVRRLLSKILDPNPKTRISITKIMENSW 265
Score = 137 bits (331), Expect = 1e-30
Identities = 72/234 (30%), Positives = 129/234 (55%), Gaps = 6/234 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID + + + REI ++ + HP++V + + + K + M Y + G+L
Sbjct: 38 VAIKIIDKEKILKVGMVDQIKREISVMRLVRHPNVVELYEVMASKTKIYFVMEYAKGGEL 97
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
V +G ++ED AR + +QL A+ + H + HRD+K EN+LL N N+K+SDFG +
Sbjct: 98 FNKVA-KGKLKEDVARKYFQQLISAVDFCHSRGVYHRDLKPENLLLDENGNLKVSDFGLS 156
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ K + + T CG+ +Y APE++ Y D+WS G+V++V+L +PF D
Sbjct: 157 ALAESKHQDGL-LHTTCGTPAYVAPEVINRKGYDGAKADIWSCGVVLFVLLAGYLPFHDS 215
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
++ +L++ K K R+ + +RL+ +L+PN + R+ I I+ + W
Sbjct: 216 NLMELYR----KIGKAEYRFPNWFPSEVRRLLSKILDPNPKTRISITKIMENSW 265
>UniRef50_P57059 Cluster: Serine/threonine-protein kinase SNF1-like
kinase 1; n=25; Euteleostomi|Rep:
Serine/threonine-protein kinase SNF1-like kinase 1 -
Homo sapiens (Human)
Length = 783
Score = 173 bits (422), Expect = 9e-42
Identities = 88/265 (33%), Positives = 150/265 (56%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + + +G+G +A V L + K+ +A KII+ + + K RE+ ++ L
Sbjct: 27 YDIERTLGKGNFAVVKLARHRVT----KTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLL 81
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHPH+I ++ + + K YI + +NG++ Y+ NG +SEN+AR Q+ ++Y H
Sbjct: 82 NHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCH 141
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ I HRD+K EN+LL N ++KL+DFGF F +P+ T+CGS YAAPE+ G
Sbjct: 142 DHHIVHRDLKTENLLLDGNMDIKLADFGFGNF--YKSGEPL--STWCGSPPYAAPEVFEG 197
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WSLGVVL+V++ S+PFD + L ++ + ++ R+ +S +C++
Sbjct: 198 KEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRF----RIPFFMSQDCES 253
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
+++ +L DP R + + W+
Sbjct: 254 LIRRMLVVDPARRITIAQIRQHRWM 278
Score = 142 bits (343), Expect = 4e-32
Identities = 74/235 (31%), Positives = 132/235 (56%), Gaps = 9/235 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID + ++K RE++++ L+HPH++ + + + + +I + + G++
Sbjct: 53 VAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEM 111
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++ G + E++AR Q+ A++Y H+ I HRD+K EN+LL N ++KL+DFGF
Sbjct: 112 FDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFG 171
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
K E S T+CGS Y APE+ +G Y D+WSLG+V+YV++ ++PF+
Sbjct: 172 NF---YKSGEPLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGP 227
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
++ L Q + +FR + +S +C+ LI ML + R+ I I W+
Sbjct: 228 NLPTLRQRVL--EGRFRIPFF--MSQDCESLIRRMLVVDPARRITIAQIRQHRWM 278
>UniRef50_O08679 Cluster: Serine/threonine-protein kinase MARK2;
n=58; Coelomata|Rep: Serine/threonine-protein kinase
MARK2 - Rattus norvegicus (Rat)
Length = 722
Score = 173 bits (420), Expect = 2e-41
Identities = 88/267 (32%), Positives = 153/267 (57%), Gaps = 17/267 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEY--SSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLV 76
Y+L K +G+G +AKV L + + KE +A KII+ + + K RE+ ++
Sbjct: 53 YRLLKTIGKGNFAKVKLARHILTGKE------VAVKIIDKTQLNSSSLQKLF-REVRIMK 105
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
LNHP+++ + + + + Y+ M Y G++ Y++ +G + E +AR RQ+ +QY
Sbjct: 106 VLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 165
Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
H+ I HRD+K EN+LL A+ N+K++DFGFS + +T+CGS YAAPE+
Sbjct: 166 CHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK----LDTFCGSPPYAAPELF 221
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
+GK Y D+WSLGV+L+ +++ S+PFD +++L E+ + KY R+ +S +C
Sbjct: 222 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKY----RIPFYMSTDC 277
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ ++K L +P R + ++ W+
Sbjct: 278 ENLLKKFLILNPSKRGTLEQIMKDRWM 304
Score = 148 bits (359), Expect = 4e-34
Identities = 75/236 (31%), Positives = 135/236 (57%), Gaps = 11/236 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID + ++K RE+ ++ L+HP++V + + ++ M Y G++
Sbjct: 79 VAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEV 137
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++ G ++E +AR RQ+ A+QY H+ I HRD+K EN+LL A+ N+K++DFGF+
Sbjct: 138 FDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFS 197
Query: 473 -RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
KL +TFCGS Y APE+ QG Y DVWSLG+++Y +++ ++PF+
Sbjct: 198 NEFTFGNKL-----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG 252
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+++K+L + + K+R + +S +C+ L+ L N R + I+ W+
Sbjct: 253 QNLKELRERVL--RGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>UniRef50_Q93Y18 Cluster: SNF1 related protein kinase; n=6;
rosids|Rep: SNF1 related protein kinase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 429
Score = 172 bits (419), Expect = 2e-41
Identities = 96/278 (34%), Positives = 159/278 (57%), Gaps = 14/278 (5%)
Query: 6 TTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVV 65
TTP++ +L Y+L + +G G++AKV+L ++ +A KIIE K + +
Sbjct: 15 TTPAK---ILLGKYELGRRLGSGSFAKVHLARSIESDE----LVAVKIIEKKKTIESGME 67
Query: 66 KFLPREIDVLVRL-NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQAR 124
+ REID + RL +HP+++ +H + K+K Y+ M G+L S +L+ G + E+ AR
Sbjct: 68 PRIIREIDAMRRLRHHPNILKIHEVMATKSKIYLVMELASGGELFSKVLRRGRLPESTAR 127
Query: 125 VWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETY 184
+ +QLA L++ H+ +AHRD+K +N+LL N+K+SDFG S + Q L T
Sbjct: 128 RYFQQLASALRFSHQDGVAHRDVKPQNLLLDEQGNLKVSDFGLS--ALPEHLQNGLLHTA 185
Query: 185 CGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRF 244
CG+ +Y APE++ + Y D WS GV+LFV+L PFDD+ + +Y + + YRF
Sbjct: 186 CGTPAYTAPEVISRRGYDGAKADAWSCGVILFVLLVGDAPFDDSNIAAMYRKIHRRDYRF 245
Query: 245 RSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
S +S + K+++ +L+P+P R S V+ + W
Sbjct: 246 ----PSWISKQAKSIIYQMLDPNPVTRMSIETVMKTNW 279
Score = 138 bits (334), Expect = 4e-31
Identities = 73/236 (30%), Positives = 132/236 (55%), Gaps = 7/236 (2%)
Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSH-PHLVHTHSIFQRRYKYFIFMRYMERG 410
++A K+I+ ++ + REI+ + +L H P+++ H + + K ++ M G
Sbjct: 50 LVAVKIIEKKKTIESGMEPRIIREIDAMRRLRHHPNILKIHEVMATKSKIYLVMELASGG 109
Query: 411 DLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFG 470
+L VL+RG + E AR + +QLA A+++ H+ +AHRD+K +N+LL N+K+SDFG
Sbjct: 110 ELFSKVLRRGRLPESTARRYFQQLASALRFSHQDGVAHRDVKPQNLLLDEQGNLKVSDFG 169
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+ + + L T CG+ +YTAPE++ Y D WS G++++V+L PF+
Sbjct: 170 LS--ALPEHLQNGLLHTACGTPAYTAPEVISRRGYDGAKADAWSCGVILFVLLVGDAPFD 227
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
D +I +++ ++++F S IS K +I ML+PN R+ I ++ + W
Sbjct: 228 DSNIAAMYRKIHRRDYRFPS----WISKQAKSIIYQMLDPNPVTRMSIETVMKTNW 279
>UniRef50_Q7Q5I9 Cluster: ENSANGP00000004268; n=3; Culicidae|Rep:
ENSANGP00000004268 - Anopheles gambiae str. PEST
Length = 725
Score = 172 bits (419), Expect = 2e-41
Identities = 93/276 (33%), Positives = 153/276 (55%), Gaps = 13/276 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G+G +A V L + S +A KII+ ++ + K REI +L L
Sbjct: 50 YELEKTIGKGNFAVVKL----ASNVITNSKVAIKIIDKTCLDEENLAKTF-REISILKVL 104
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HPH+ ++ + + + K Y+ + G++ +++ NG + E +A Q+ + Y H
Sbjct: 105 HHPHITRLYEVMESRNKIYLVTEHAAQGEIFDHLVANGRMREEEAARIFSQIVAAVDYCH 164
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K ENVLL + NVKL+DFGFS VE QP+ T+CGS YAAPE+ +G
Sbjct: 165 RKGIVHRDLKAENVLLDTDMNVKLADFGFSNTFVE--GQPL--RTWCGSPPYAAPEVFQG 220
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y +D+WSLGVVL+V++ ++PFD T + L + K+ R+ +S EC+
Sbjct: 221 VEYDGPKSDIWSLGVVLYVLVCGALPFDGTTLHDLRSVVVAGKF----RIPFFMSQECEQ 276
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNA 294
+++H+L +P R++ + W+A + + L A
Sbjct: 277 LIRHMLVVEPERRYTLKQIAHHRWLAQYNSIPMLEA 312
Score = 148 bits (358), Expect = 5e-34
Identities = 80/238 (33%), Positives = 132/238 (55%), Gaps = 9/238 (3%)
Query: 351 SILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERG 410
S +A K+ID + + + K REI +L L HPH+ + + + R K ++ + +G
Sbjct: 74 SKVAIKIIDKTCLDEENLAKTF-REISILKVLHHPHITRLYEVMESRNKIYLVTEHAAQG 132
Query: 411 DLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFG 470
++ + ++ G ++E++A Q+ A+ Y H I HRD+K ENVLL + NVKL+DFG
Sbjct: 133 EIFDHLVANGRMREEEAARIFSQIVAAVDYCHRKGIVHRDLKAENVLLDTDMNVKLADFG 192
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
F+ V+ + +R T+CGS Y APE+ QG Y +D+WSLG+V+YV++ A+PF+
Sbjct: 193 FSNTFVEGQ--PLR--TWCGSPPYAAPEVFQGVEYDGPKSDIWSLGVVLYVLVCGALPFD 248
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
+ L + KFR + +S C++LI ML + R + I + W+A
Sbjct: 249 GTTLHDLRSVVV--AGKFRIPFF--MSQECEQLIRHMLVVEPERRYTLKQIAHHRWLA 302
>UniRef50_A7SZV3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 652
Score = 172 bits (419), Expect = 2e-41
Identities = 88/276 (31%), Positives = 157/276 (56%), Gaps = 17/276 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEY--SSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLV 76
Y+L K +G+G +AKV L ++ + KE +A KII+ + + K RE+ ++
Sbjct: 38 YRLIKTIGKGNFAKVKLAKHVPTGKE------VAIKIIDKTQLNPSSLQKLF-REVRIMK 90
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
L+HP+++ ++ + + Y+ M Y G++ Y++ +G + E +AR RQ+ +QY
Sbjct: 91 FLDHPNIVKLYEVIETDKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQY 150
Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
H+ + HRD+K EN+LL A+ N+K++DFGFS + +T+CGS YAAPE+
Sbjct: 151 CHQKHVIHRDLKAENLLLDADMNIKIADFGFSNEFTPGNK----LDTFCGSPPYAAPELF 206
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
+GK Y D+WSLGV+L+ +++ S+PFD +++L E+ + KY R+ +S +C
Sbjct: 207 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKY----RIPFYMSTDC 262
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTL 292
+ ++K L +P R + +W+ ++ L L
Sbjct: 263 ENLLKKFLVLNPQKRARLEQTMTDKWMNINYELNEL 298
Score = 155 bits (377), Expect = 3e-36
Identities = 78/247 (31%), Positives = 141/247 (57%), Gaps = 11/247 (4%)
Query: 353 LACKVID-TSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A K+ID T P K F RE+ ++ L HP++V + + + ++ M Y G+
Sbjct: 64 VAIKIIDKTQLNPSSLQKLF--REVRIMKFLDHPNIVKLYEVIETDKTLYLVMEYASGGE 121
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
+ ++++ G ++E +AR RQ+ A+QY H+ + HRD+K EN+LL A+ N+K++DFGF
Sbjct: 122 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHVIHRDLKAENLLLDADMNIKIADFGF 181
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+ + +TFCGS Y APE+ QG Y DVWSLG+++Y +++ ++PF+
Sbjct: 182 SNEFTPGN----KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDG 237
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDS 591
+++K+L + + K+R + +S +C+ L+ L N Q R ++ + +W+ ++
Sbjct: 238 QNLKELRERVL--RGKYRIPFY--MSTDCENLLKKFLVLNPQKRARLEQTMTDKWMNINY 293
Query: 592 RLLEWTP 598
L E P
Sbjct: 294 ELNELKP 300
>UniRef50_Q9W532 Cluster: CG4290-PA; n=8; Coelomata|Rep: CG4290-PA -
Drosophila melanogaster (Fruit fly)
Length = 1398
Score = 171 bits (417), Expect = 4e-41
Identities = 87/265 (32%), Positives = 151/265 (56%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + + +G+G +A V L + K+ +A KII+ ++ + + K RE++++ RL
Sbjct: 141 YDIERTIGKGNFAVVKLARHRIT----KNEVAIKIIDKSQLDQTNLQKVY-REVEIMKRL 195
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++ + + K YI Y G++ YI K G +SE+ AR Q+ ++Y H
Sbjct: 196 KHPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCH 255
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ I HRD+K EN+LL N N+K++DFGFS + L T+CGS YAAPE+ G
Sbjct: 256 KKGIVHRDLKAENLLLDLNMNIKIADFGFSNHFKPGE----LLATWCGSPPYAAPEVFEG 311
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WSLGVVL+V++ ++PFD + ++ L ++ + ++ R+ +S EC+
Sbjct: 312 KQYTGPEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRF----RIPFFMSSECEH 367
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
+++ +L +P R++ + W+
Sbjct: 368 LIRRMLVLEPTRRYTIDQIKRHRWM 392
Score = 147 bits (357), Expect = 7e-34
Identities = 82/252 (32%), Positives = 140/252 (55%), Gaps = 14/252 (5%)
Query: 336 VYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQ 395
V LA +R +KN+ +A K+ID S + ++K RE+E++ +L HPH++ + + +
Sbjct: 155 VKLARHR-ITKNE----VAIKIIDKSQLDQTNLQKVY-REVEIMKRLKHPHIIKLYQVME 208
Query: 396 RRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCEN 455
+ +I Y +G++ +++ + G + E AR Q+ A++Y H+ I HRD+K EN
Sbjct: 209 TKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKAEN 268
Query: 456 VLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSL 515
+LL N N+K++DFGF+ K E+ + T+CGS Y APE+ +G Y D+WSL
Sbjct: 269 LLLDLNMNIKIADFGFSN---HFKPGELLA-TWCGSPPYAAPEVFEGKQYTGPEIDIWSL 324
Query: 516 GIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNR 575
G+V+YV++ A+PF+ ++ L + + +FR + +S C+ LI ML R
Sbjct: 325 GVVLYVLVCGALPFDGSTLQSLRDRVL--SGRFRIPFF--MSSECEHLIRRMLVLEPTRR 380
Query: 576 LKIYDIVNSEWI 587
I I W+
Sbjct: 381 YTIDQIKRHRWM 392
>UniRef50_O61821 Cluster: Temporarily assigned gene name protein
344; n=4; Caenorhabditis|Rep: Temporarily assigned gene
name protein 344 - Caenorhabditis elegans
Length = 367
Score = 171 bits (417), Expect = 4e-41
Identities = 95/267 (35%), Positives = 144/267 (53%), Gaps = 14/267 (5%)
Query: 20 KLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETA--KAPKDFVVKFLPREIDVLVR 77
K K +G G+Y++V + K K +A KII + +D++ KFLPRE +++
Sbjct: 70 KFEKVLGSGSYSRVARATFGEK----KLEVAAKIINITPTREKEDYIKKFLPREKEIVKL 125
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
L H ++ ++ + + Y GDLL + + E A+ RQL L +L
Sbjct: 126 LKHDNICRLYEMISFQDHIIFVNEYCAGGDLLRKMKDIVAMKEEDAKFTFRQLIAALTHL 185
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
I HRD+KCEN+ + + NVKL DFGFSR + S T+CGS +Y APEI R
Sbjct: 186 QSYNIVHRDLKCENIFMDKHGNVKLGDFGFSRILKPGEK----SGTFCGSRAYVAPEIFR 241
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRF-RSRVASILSLEC 256
G+ Y D+WS GV+L++ML SMPFDD RK+ E+Q+ K +F +S +S+ S
Sbjct: 242 GREYSGNAVDVWSTGVILYIMLAGSMPFDDRDPRKMIERQLAHKIKFPKSCTSSVFS--- 298
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWI 283
K +V +L+P R + + +SEW+
Sbjct: 299 KALVLEILQPHAPNRPTYKAICESEWL 325
Score = 155 bits (375), Expect = 5e-36
Identities = 87/246 (35%), Positives = 138/246 (56%), Gaps = 8/246 (3%)
Query: 344 ASKNDKLSILACKVID-TSTAPR-DFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYF 401
A+ +K +A K+I+ T T + D++KKFLPRE E++ L H ++ + + +
Sbjct: 86 ATFGEKKLEVAAKIINITPTREKEDYIKKFLPREKEIVKLLKHDNICRLYEMISFQDHII 145
Query: 402 IFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTAN 461
Y GDLL + A++E+ A+ RQL A+ ++ I HRD+KCEN+ + +
Sbjct: 146 FVNEYCAGGDLLRKMKDIVAMKEEDAKFTFRQLIAALTHLQSYNIVHRDLKCENIFMDKH 205
Query: 462 QNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYV 521
NVKL DFGF+R+ K E +S TFCGS +Y APEI +G Y DVWS G+++Y+
Sbjct: 206 GNVKLGDFGFSRIL---KPGE-KSGTFCGSRAYVAPEIFRGREYSGNAVDVWSTGVILYI 261
Query: 522 MLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDI 581
ML +MPF+D+ +++ + Q+ KF ++ K L+ +L+P+ NR I
Sbjct: 262 MLAGSMPFDDRDPRKMIERQLAHKIKFPKSCTSSVFS--KALVLEILQPHAPNRPTYKAI 319
Query: 582 VNSEWI 587
SEW+
Sbjct: 320 CESEWL 325
>UniRef50_Q9P0L2 Cluster: Serine/threonine-protein kinase MARK1;
n=73; Euteleostomi|Rep: Serine/threonine-protein kinase
MARK1 - Homo sapiens (Human)
Length = 795
Score = 171 bits (417), Expect = 4e-41
Identities = 89/266 (33%), Positives = 152/266 (57%), Gaps = 15/266 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G+G +AKV L + +A KII+ + + K RE+ ++ L
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGRE----VAVKIIDKTQLNPTSLQKLF-REVRIMKIL 114
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHP+++ + + + + Y+ M Y G++ Y++ +G + E +AR RQ+ +QY H
Sbjct: 115 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 174
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFS-RFCVESDNQPVLSETYCGSMSYAAPEILR 197
+ I HRD+K EN+LL + N+K++DFGFS F V + +T+CGS YAAPE+ +
Sbjct: 175 QKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK-----LDTFCGSPPYAAPELFQ 229
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
GK Y D+WSLGV+L+ +++ S+PFD +++L E+ + KY R+ +S +C+
Sbjct: 230 GKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKY----RIPFYMSTDCE 285
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWI 283
++K LL +P R S ++ W+
Sbjct: 286 NLLKKLLVLNPIKRGSLEQIMKDRWM 311
Score = 150 bits (363), Expect = 1e-34
Identities = 78/237 (32%), Positives = 136/237 (57%), Gaps = 13/237 (5%)
Query: 353 LACKVID-TSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A K+ID T P K F RE+ ++ L+HP++V + + ++ M Y G+
Sbjct: 86 VAVKIIDKTQLNPTSLQKLF--REVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGE 143
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
+ ++++ G ++E +AR RQ+ A+QY H+ I HRD+K EN+LL + N+K++DFGF
Sbjct: 144 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF 203
Query: 472 A-RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+ V KL +TFCGS Y APE+ QG Y DVWSLG+++Y +++ ++PF+
Sbjct: 204 SNEFTVGNKL-----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD 258
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+++K+L + + K+R + +S +C+ L+ +L N R + I+ W+
Sbjct: 259 GQNLKELRERVL--RGKYRIPFY--MSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 311
>UniRef50_Q96L34 Cluster: MAP/microtubule affinity-regulating kinase
4; n=19; Euteleostomi|Rep: MAP/microtubule
affinity-regulating kinase 4 - Homo sapiens (Human)
Length = 752
Score = 171 bits (415), Expect = 7e-41
Identities = 87/266 (32%), Positives = 152/266 (57%), Gaps = 15/266 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L + +G+G +AKV L + +A KII+ + + K RE+ ++ L
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGRE----VAIKIIDKTQLNPSSLQKLF-REVRIMKGL 113
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHP+++ + + + + Y+ M Y G++ Y++ +G + E +AR RQ+ + Y H
Sbjct: 114 NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCH 173
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFS-RFCVESDNQPVLSETYCGSMSYAAPEILR 197
+ I HRD+K EN+LL A N+K++DFGFS F + S +T+CGS YAAPE+ +
Sbjct: 174 QKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSK-----LDTFCGSPPYAAPELFQ 228
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
GK Y D+WSLGV+L+ +++ S+PFD +++L E+ + KY RV +S +C+
Sbjct: 229 GKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKY----RVPFYMSTDCE 284
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWI 283
++++ L +P R + ++ +WI
Sbjct: 285 SILRRFLVLNPAKRCTLEQIMKDKWI 310
Score = 149 bits (362), Expect = 2e-34
Identities = 76/237 (32%), Positives = 134/237 (56%), Gaps = 13/237 (5%)
Query: 353 LACKVID-TSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A K+ID T P K F RE+ ++ L+HP++V + + ++ M Y G+
Sbjct: 85 VAIKIIDKTQLNPSSLQKLF--REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGE 142
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
+ ++++ G ++E +AR RQ+ A+ Y H+ I HRD+K EN+LL A N+K++DFGF
Sbjct: 143 VFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGF 202
Query: 472 A-RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+ + KL +TFCGS Y APE+ QG Y D+WSLG+++Y +++ ++PF+
Sbjct: 203 SNEFTLGSKL-----DTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFD 257
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
++K+L + + K+R + +S +C+ ++ L N R + I+ +WI
Sbjct: 258 GHNLKELRERVL--RGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKDKWI 310
>UniRef50_Q9H093 Cluster: NUAK family SNF1-like kinase 2; n=31;
Euteleostomi|Rep: NUAK family SNF1-like kinase 2 - Homo
sapiens (Human)
Length = 628
Score = 169 bits (411), Expect = 2e-40
Identities = 92/265 (34%), Positives = 146/265 (55%), Gaps = 14/265 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+ + +G+G Y KV ++E S + +A K I K + + + REI+++ L
Sbjct: 53 YEFLETLGKGTYGKVK----KARESSGR-LVAIKSIRKDKIKDEQDLMHIRREIEIMSSL 107
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHPH+I +H +F+ +K I M Y GDL YI + +SE +AR + RQ+ + Y H
Sbjct: 108 NHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCH 167
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ + HRD+K EN+LL AN N+K++DFG S +Q +T+CGS YA+PEI+ G
Sbjct: 168 QNRVVHRDLKLENILLDANGNIKIADFGLSNLY----HQGKFLQTFCGSPLYASPEIVNG 223
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
KPY D WSLGV+L+++++ +MPFD + L +Q YR + + L
Sbjct: 224 KPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDACGL---- 279
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
++ LL +P R + +V W+
Sbjct: 280 -IRWLLMVNPTRRATLEDVASHWWV 303
Score = 156 bits (378), Expect = 2e-36
Identities = 80/214 (37%), Positives = 124/214 (57%), Gaps = 9/214 (4%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
REIE++ L+HPH++ H +F+ K I M Y RGDL +++ +R + E +AR + RQ
Sbjct: 99 REIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQ 158
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+ A+ Y H+ + HRD+K EN+LL AN N+K++DFG + + K +TFCGS
Sbjct: 159 IVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKF----LQTFCGSPL 214
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y +PEI+ G PY D WSLG+++Y++++ MPF D H ++ QI+ N +R
Sbjct: 215 YASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPF-DGHDHKILVKQIS-NGAYREP-- 270
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
SD C LI +L N R + D+ + W+
Sbjct: 271 PKPSDAC-GLIRWLLMVNPTRRATLEDVASHWWV 303
>UniRef50_Q7R9H7 Cluster: Serine/threonine-protein kinase; n=3;
Plasmodium (Vinckeia)|Rep: Serine/threonine-protein
kinase - Plasmodium yoelii yoelii
Length = 996
Score = 169 bits (410), Expect = 3e-40
Identities = 91/275 (33%), Positives = 152/275 (55%), Gaps = 12/275 (4%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP 69
+ N + Y + K +G+G + KV L ++ + +A KI+ K + +
Sbjct: 492 KSNNIEVGNYIIIKNIGKGTFGKVCLGMHTYTYE----IVAIKILNKKKLLRIISYDKIL 547
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
REI + +++H H+ + + + K Y+ + Y NGDLL+YI KN ++EN + Q
Sbjct: 548 REIKIHKKIDHNHICRFYEVHENKNNIYMILEYLGNGDLLTYICKNSNINENIGKRILYQ 607
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
L ++YLH++ I HRD+K EN+LL N N+KL DFG S + S N +T CGS
Sbjct: 608 LISAIEYLHKINIVHRDLKPENILLDHNNNIKLIDFGLS--TIYSKNN--FLQTSCGSPF 663
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
Y PEIL GK Y P+ TD+WSLG++LF++LNK +PF+ + KL++Q + +F V
Sbjct: 664 YTPPEILLGKKYNPELTDVWSLGIILFLLLNKKLPFNHNDINKLFQQIIKGLMQFEPHV- 722
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIA 284
S+ K +++++L + R++ + + W +
Sbjct: 723 ---SINAKNLIQNMLNVNCKNRYNLNQIKNHIWFS 754
Score = 152 bits (369), Expect = 2e-35
Identities = 83/237 (35%), Positives = 131/237 (55%), Gaps = 8/237 (3%)
Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
I+A K+++ R + REI++ K+ H H+ + + + + ++ + Y+ GD
Sbjct: 526 IVAIKILNKKKLLRIISYDKILREIKIHKKIDHNHICRFYEVHENKNNIYMILEYLGNGD 585
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
LL ++ + + E+ + QL AI+Y+H++ I HRD+K EN+LL N N+KL DFG
Sbjct: 586 LLTYICKNSNINENIGKRILYQLISAIEYLHKINIVHRDLKPENILLDHNNNIKLIDFGL 645
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+ + K N + +T CGS YT PEIL G Y P+ TDVWSLGI+++++LN+ +PF
Sbjct: 646 S--TIYSKNNFL--QTSCGSPFYTPPEILLGKKYNPELTDVWSLGIILFLLLNKKLPFNH 701
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
I +L Q I +F +S N K LI ML N +NR + I N W +
Sbjct: 702 NDINKLFQQIIKGLMQFEPH----VSINAKNLIQNMLNVNCKNRYNLNQIKNHIWFS 754
>UniRef50_Q6P4S6 Cluster: Serine/threonine-protein kinase QSK; n=21;
Eumetazoa|Rep: Serine/threonine-protein kinase QSK - Mus
musculus (Mouse)
Length = 1311
Score = 169 bits (410), Expect = 3e-40
Identities = 87/290 (30%), Positives = 162/290 (55%), Gaps = 14/290 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y++ + +G+G +A V + K+ +A KII+ ++ ++ + K RE+ ++ L
Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVT----KAKVAIKIIDKSQLDEENLKKIF-REVQIMKML 62
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++ + + + Y+ Y G++ +++ +G ++E +AR +Q+ + + H
Sbjct: 63 CHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCH 122
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K EN+LL AN N+K++DFGFS L +T+CGS YAAPE+ G
Sbjct: 123 CRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ----LLKTWCGSPPYAAPELFEG 178
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WSLGVVL+V++ ++PFD + ++ L + + K+ R+ +S EC+
Sbjct: 179 KEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKF----RIPFFMSTECEH 234
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKEDRR 308
+++H+L DP R S + +W+ + + + A ++ KE+R+
Sbjct: 235 LIRHMLVLDPNKRLSMEQICRHKWMKLGDADPNFDRL-IAECQQLKEERQ 283
Score = 147 bits (356), Expect = 9e-34
Identities = 76/237 (32%), Positives = 135/237 (56%), Gaps = 9/237 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID S + +KK RE++++ L HPH++ + + + ++ Y G++
Sbjct: 34 VAIKIIDKSQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEI 92
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ ++ G + E +AR +Q+ A+ + H I HRD+K EN+LL AN N+K++DFGF+
Sbjct: 93 FDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFS 152
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ +L +T+CGS Y APE+ +G Y D+WSLG+V+YV++ A+PF+
Sbjct: 153 NLFTPGQL----LKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGS 208
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAM 589
++ L +A++ + KFR + +S C+ LI ML + RL + I +W+ +
Sbjct: 209 TLQNL-RARV-LSGKFRIPFF--MSTECEHLIRHMLVLDPNKRLSMEQICRHKWMKL 261
>UniRef50_Q9Y2K2 Cluster: Serine/threonine-protein kinase QSK; n=15;
Euteleostomi|Rep: Serine/threonine-protein kinase QSK -
Homo sapiens (Human)
Length = 1263
Score = 169 bits (410), Expect = 3e-40
Identities = 87/290 (30%), Positives = 161/290 (55%), Gaps = 14/290 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y++ + +G+G +A V + K+ +A KII+ + ++ + K RE+ ++ L
Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVT----KAKVAIKIIDKTQLDEENLKKIF-REVQIMKML 62
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++ + + + Y+ Y G++ +++ +G ++E +AR +Q+ + + H
Sbjct: 63 CHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCH 122
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K EN+LL AN N+K++DFGFS L +T+CGS YAAPE+ G
Sbjct: 123 CRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ----LLKTWCGSPPYAAPELFEG 178
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WSLGVVL+V++ ++PFD + ++ L + + K+ R+ +S EC+
Sbjct: 179 KEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKF----RIPFFMSTECEH 234
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKEDRR 308
+++H+L DP R S + +W+ + + + A ++ KE+R+
Sbjct: 235 LIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNFDRL-IAECQQLKEERQ 283
Score = 146 bits (353), Expect = 2e-33
Identities = 75/237 (31%), Positives = 135/237 (56%), Gaps = 9/237 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID + + +KK RE++++ L HPH++ + + + ++ Y G++
Sbjct: 34 VAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEI 92
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ ++ G + E +AR +Q+ A+ + H I HRD+K EN+LL AN N+K++DFGF+
Sbjct: 93 FDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFS 152
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ +L +T+CGS Y APE+ +G Y D+WSLG+V+YV++ A+PF+
Sbjct: 153 NLFTPGQL----LKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGS 208
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAM 589
++ L +A++ + KFR + +S C+ LI ML + RL + I +W+ +
Sbjct: 209 TLQNL-RARV-LSGKFRIPFF--MSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKL 261
>UniRef50_Q8MVX2 Cluster: Putative serine/threonine protein kinase;
n=3; Haemonchus contortus|Rep: Putative serine/threonine
protein kinase - Haemonchus contortus (Barber pole worm)
Length = 966
Score = 168 bits (409), Expect = 4e-40
Identities = 85/257 (33%), Positives = 149/257 (57%), Gaps = 15/257 (5%)
Query: 28 GAYAKVYLTEYSSKEDSHKSTLACKIIE-TAKAPKDFVVKFLPREIDVLVRLNHPHLIHV 86
G +AKV L +++ +A KII+ TA P F RE+ ++ +L+HP+++ +
Sbjct: 1 GNFAKVKLAKHTITGQE----VAIKIIDKTALNPSSLQKLF--REVKIMKQLDHPNIVKL 54
Query: 87 HSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAHRD 146
+ + + + Y+ + Y G++ Y++ +G + E +ARV RQ+ +QYLH I HRD
Sbjct: 55 YQVMENEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARVKFRQIVSAVQYLHSKNIIHRD 114
Query: 147 IKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPT 206
+K EN+LL A+ N+K++DFGFS + +T+CGS YAAPE+ +GK Y
Sbjct: 115 LKAENLLLDADMNIKIADFGFSNQFTLGNK----LDTFCGSPPYAAPELFQGKKYDGPEV 170
Query: 207 DLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEP 266
D+WSLGV+L+ +++ S+PFD +++L E+ + KY R+ +S +C+ ++K L
Sbjct: 171 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKY----RIPFYMSTDCENLLKKFLVL 226
Query: 267 DPGLRHSATNVLDSEWI 283
+P R + ++ W+
Sbjct: 227 NPARRGTLETIMKDRWM 243
Score = 155 bits (376), Expect = 4e-36
Identities = 77/237 (32%), Positives = 141/237 (59%), Gaps = 13/237 (5%)
Query: 353 LACKVID-TSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A K+ID T+ P K F RE++++ +L HP++V + + + ++ + Y G+
Sbjct: 18 VAIKIIDKTALNPSSLQKLF--REVKIMKQLDHPNIVKLYQVMENEQTLYLVLEYASGGE 75
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
+ ++++ G ++E +AR+ RQ+ A+QY+H I HRD+K EN+LL A+ N+K++DFGF
Sbjct: 76 VFDYLVAHGRMKEKEARVKFRQIVSAVQYLHSKNIIHRDLKAENLLLDADMNIKIADFGF 135
Query: 472 A-RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+ + + KL +TFCGS Y APE+ QG Y DVWSLG+++Y +++ ++PF+
Sbjct: 136 SNQFTLGNKL-----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD 190
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+++K+L + + K+R + +S +C+ L+ L N R + I+ W+
Sbjct: 191 GQNLKELRERVL--RGKYRIPFY--MSTDCENLLKKFLVLNPARRGTLETIMKDRWM 243
>UniRef50_UPI0000E4986C Cluster: PREDICTED: similar to KIAA0999
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to KIAA0999 protein -
Strongylocentrotus purpuratus
Length = 1066
Score = 167 bits (407), Expect = 6e-40
Identities = 82/238 (34%), Positives = 140/238 (58%), Gaps = 9/238 (3%)
Query: 49 LACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDL 108
+A KII+ + D + K + RE+ V+ L+HPH+I ++ + + Y+ Y G++
Sbjct: 17 VAIKIIDKTQLEGDNIQKIV-REVKVMKLLSHPHIIRLYQVMETDRYMYLVTEYASGGEI 75
Query: 109 LSYILKNGCVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFS 168
+++ +G ++E +AR +Q+ + Y H+ I HRD+K EN+LL AN NVK++DFGFS
Sbjct: 76 FDHLISHGKMTEREARQKFKQIVAAVHYCHKRGIVHRDLKAENLLLDANMNVKIADFGFS 135
Query: 169 RFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDT 228
F E D+ L +T+CGS YAAPE+ G+ Y D+WSLGVVL+V+++ ++PFD
Sbjct: 136 NF-FEKDH---LLKTWCGSPPYAAPELFEGREYNGPKADVWSLGVVLYVLVSGALPFDGK 191
Query: 229 RMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMD 286
+ L + + ++ R+ +S C+ +++H+L D R++ VL+ W D
Sbjct: 192 TLHNLRARVLSGQF----RIPFFMSEGCEDLIRHMLILDASRRYTTDQVLNHRWTKGD 245
Score = 150 bits (364), Expect = 1e-34
Identities = 82/239 (34%), Positives = 138/239 (57%), Gaps = 11/239 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQR-RYKYFIFMRYMERGD 411
+A K+ID + D ++K + RE++++ LSHPH++ + + + RY Y + Y G+
Sbjct: 17 VAIKIIDKTQLEGDNIQKIV-REVKVMKLLSHPHIIRLYQVMETDRYMYLV-TEYASGGE 74
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
+ + ++ G + E +AR +Q+ A+ Y H+ I HRD+K EN+LL AN NVK++DFGF
Sbjct: 75 IFDHLISHGKMTEREARQKFKQIVAAVHYCHKRGIVHRDLKAENLLLDANMNVKIADFGF 134
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+ L +T+CGS Y APE+ +G Y DVWSLG+V+YV+++ A+PF+
Sbjct: 135 SNFFEKDHL----LKTWCGSPPYAAPELFEGREYNGPKADVWSLGVVLYVLVSGALPFDG 190
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
K + L +A++ + +FR + +S+ C+ LI ML + R ++N W D
Sbjct: 191 KTLHNL-RARV-LSGQFRIPFF--MSEGCEDLIRHMLILDASRRYTTDQVLNHRWTKGD 245
>UniRef50_Q22SK1 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1114
Score = 167 bits (407), Expect = 6e-40
Identities = 90/269 (33%), Positives = 155/269 (57%), Gaps = 13/269 (4%)
Query: 10 EENTLLTKG-YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68
+ ++++T G +++ + +G G + KV L + + +A K+++ K K L
Sbjct: 40 QAHSIVTVGNFEIGQTIGRGTFGKVKLGIHKITNEK----VAVKVLDKDKLIDSADKKRL 95
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTR 128
REI +L ++ HP++I ++ I + + Y+FM Y NG+L YI+K +SE QA + +
Sbjct: 96 QREISILRKIRHPNIIQLYEIIETPRQLYLFMEYAPNGELFDYIVKRTRLSERQASKFLQ 155
Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
Q+ G++Y+ ++ + HRD+K EN+LL N+N+K+ DFG S DN+ + +T CGS
Sbjct: 156 QIINGIEYMSKIGVVHRDLKPENLLLDHNYNIKIVDFGLSN--TYKDNEKL--KTACGSP 211
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
YAAPE++ GKPY TD+WS GV+L+ ML +PF+D LY++ M + +
Sbjct: 212 CYAAPEMVAGKPYNGLQTDIWSSGVILYAMLCGYLPFEDQNTSVLYKKIMNQD----PVL 267
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNV 277
S LS K ++ +L DP R++ ++
Sbjct: 268 PSFLSSNSKGILSGILTKDPEKRYNIQDI 296
Score = 148 bits (358), Expect = 5e-34
Identities = 79/229 (34%), Positives = 132/229 (57%), Gaps = 8/229 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KV+D KK L REI +L K+ HP+++ + I + + ++FM Y G+L
Sbjct: 76 VAVKVLDKDKLIDSADKKRLQREISILRKIRHPNIIQLYEIIETPRQLYLFMEYAPNGEL 135
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++++R + E QA + +Q+ I+YM ++ + HRD+K EN+LL N N+K+ DFG +
Sbjct: 136 FDYIVKRTRLSERQASKFLQQIINGIEYMSKIGVVHRDLKPENLLLDHNYNIKIVDFGLS 195
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
D NE + +T CGS Y APE++ G PY TD+WS G+++Y ML +PFED+
Sbjct: 196 NTYKD---NE-KLKTACGSPCYAAPEMVAGKPYNGLQTDIWSSGVILYAMLCGYLPFEDQ 251
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDI 581
+ L++ +N++ S +S N K ++ +L + + R I DI
Sbjct: 252 NTSVLYKKIMNQDPVLPS----FLSSNSKGILSGILTKDPEKRYNIQDI 296
>UniRef50_UPI00015B41D5 Cluster: PREDICTED: hypothetical protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
protein - Nasonia vitripennis
Length = 809
Score = 167 bits (406), Expect = 8e-40
Identities = 85/266 (31%), Positives = 152/266 (57%), Gaps = 13/266 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + +G+G +A V L + K+ +A KII+ ++ + K RE++++ +L
Sbjct: 17 YDIEGTIGKGNFAVVKLARHRIT----KTEVAIKIIDKSQLDPTNLEKVY-REVEIMKQL 71
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH++ ++ + + K Y+ Y G++ YI + G + E +AR Q+ ++Y H
Sbjct: 72 EHPHIVKLYQVMETKNMLYMVCEYASRGEIFDYIARYGRMGEPRARATFAQILSAVEYCH 131
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+AHRD+K EN+LL A VK++DFGFS + LS T+CGS YAAPE+ RG
Sbjct: 132 ATGVAHRDLKAENLLLDAQMCVKIADFGFSNRFAPGER---LS-TWCGSPPYAAPEVFRG 187
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WSLGVVL+V++ ++PFD + ++ L ++ + ++ R+ +S +C++
Sbjct: 188 KHYAGPEIDVWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRF----RIPYFMSTDCES 243
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIA 284
+++ +L +PG R++ + W+A
Sbjct: 244 LIRKMLVLEPGKRYTIPQIKRHRWMA 269
Score = 147 bits (355), Expect = 1e-33
Identities = 79/236 (33%), Positives = 130/236 (55%), Gaps = 9/236 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID S ++K RE+E++ +L HPH+V + + + + ++ Y RG++
Sbjct: 43 VAIKIIDKSQLDPTNLEKVY-REVEIMKQLEHPHIVKLYQVMETKNMLYMVCEYASRGEI 101
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++ + G + E +AR Q+ A++Y H +AHRD+K EN+LL A VK++DFGF+
Sbjct: 102 FDYIARYGRMGEPRARATFAQILSAVEYCHATGVAHRDLKAENLLLDAQMCVKIADFGFS 161
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ R T+CGS Y APE+ +G Y DVWSLG+V+YV++ A+PF+
Sbjct: 162 NRFAPGE----RLSTWCGSPPYAAPEVFRGKHYAGPEIDVWSLGVVLYVLVCGALPFDGS 217
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
++ L + + +FR Y +S +C+ LI ML R I I W+A
Sbjct: 218 TLQSLRDRVL--SGRFRIPYF--MSTDCESLIRKMLVLEPGKRYTIPQIKRHRWMA 269
>UniRef50_A0D0C4 Cluster: Chromosome undetermined scaffold_33, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_33,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 595
Score = 167 bits (406), Expect = 8e-40
Identities = 93/273 (34%), Positives = 150/273 (54%), Gaps = 14/273 (5%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP 69
+E+TL Y + +GEG + KV + + + +A KI+E AK + V +
Sbjct: 2 QESTL--GNYAIGNTLGEGTFGKVKMGTHLQSGEK----VAIKILEKAKFEDESDVYRIA 55
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
+EI++L +L HPH+I ++ I + Y+ M Y G+L YI+KN VSE A + Q
Sbjct: 56 KEIEILKKLRHPHIIQIYEIIDTDKEIYLIMEYASGGELFEYIVKNHRVSEKIACRFLLQ 115
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
+ G++Y+H++ I HRD+K EN+L N N+K+ DFG S ++ L +T CGS
Sbjct: 116 ILSGVEYMHKIGIVHRDLKPENLLFDNNQNIKIVDFGLSNTYKPNE----LLKTACGSPC 171
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
YAAPE+++G Y D+WS G+VL+ ML +PF+D +LY++ + F
Sbjct: 172 YAAPEMIQGLKYSGYLIDIWSCGIVLYAMLCGYLPFEDQNTNQLYKKIVAGDLVF----P 227
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
LS+E K ++K++L DP R + + +W
Sbjct: 228 KWLSIEAKDLLKNILNTDPKKRFTIPQIKGHKW 260
Score = 138 bits (333), Expect = 6e-31
Identities = 75/215 (34%), Positives = 119/215 (55%), Gaps = 8/215 (3%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ +EIE+L KL HPH++ + I + ++ M Y G+L E++++ V E A +
Sbjct: 54 IAKEIEILKKLRHPHIIQIYEIIDTDKEIYLIMEYASGGELFEYIVKNHRVSEKIACRFL 113
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
Q+ ++YMH++ I HRD+K EN+L NQN+K+ DFG + K NE+ +T CGS
Sbjct: 114 LQILSGVEYMHKIGIVHRDLKPENLLFDNNQNIKIVDFGLSN---TYKPNEL-LKTACGS 169
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y APE++QG Y D+WS GIV+Y ML +PFED++ QL++ + + F
Sbjct: 170 PCYAAPEMIQGLKYSGYLIDIWSCGIVLYAMLCGYLPFEDQNTNQLYKKIVAGDLVFPK- 228
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+S K L+ +L + + R I I +W
Sbjct: 229 ---WLSIEAKDLLKNILNTDPKKRFTIPQIKGHKW 260
>UniRef50_A0CKQ4 Cluster: Chromosome undetermined scaffold_2, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_2,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 576
Score = 167 bits (406), Expect = 8e-40
Identities = 86/264 (32%), Positives = 155/264 (58%), Gaps = 14/264 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + K +G+G ++KV + ++ H++ A K++E ++ V+ + REI +L L
Sbjct: 7 YLIGKTIGQGTFSKV--CQAINQVIGHEA--AVKVLEKKCINQEGDVERVKREIQILKVL 62
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP ++ ++ + + + Y+FM Y G+L YI + V+E +A + Q+ GL+Y+H
Sbjct: 63 HHPQIVKLYEVIETENHIYLFMEYANGGELFDYIDRVKQVTEYEACKFLHQIISGLEYMH 122
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
L+I HRD+K EN+LLT++ ++ ++DFG S Q L +T CGS YAAPE+++G
Sbjct: 123 SLKIIHRDLKPENLLLTSDRDILIADFGLSNL------QKDLLKTCCGSTCYAAPEMIQG 176
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+PY + TD+WS G++LF M+ +PFDD + LY++ ++ F + S++ K
Sbjct: 177 EPYDGQMTDVWSCGIILFAMICGYLPFDDLNTQNLYQKITNAEFTFPKHI----SMDAKD 232
Query: 259 VVKHLLEPDPGLRHSATNVLDSEW 282
+++ +L DP R+S + +W
Sbjct: 233 LLRRILVVDPQKRYSIQQIKRHKW 256
Score = 138 bits (335), Expect = 3e-31
Identities = 75/233 (32%), Positives = 130/233 (55%), Gaps = 10/233 (4%)
Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLL 413
A KV++ ++ + + REI++L L HP +V + + + ++FM Y G+L
Sbjct: 34 AVKVLEKKCINQEGDVERVKREIQILKVLHHPQIVKLYEVIETENHIYLFMEYANGGELF 93
Query: 414 EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFAR 473
+++ + V E +A + Q+ ++YMH L+I HRD+K EN+LLT+++++ ++DFG +
Sbjct: 94 DYIDRVKQVTEYEACKFLHQIISGLEYMHSLKIIHRDLKPENLLLTSDRDILIADFGLSN 153
Query: 474 MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKH 533
+ D +T CGS Y APE++QG PY + TDVWS GI+++ M+ +PF+D +
Sbjct: 154 LQKD------LLKTCCGSTCYAAPEMIQGEPYDGQMTDVWSCGIILFAMICGYLPFDDLN 207
Query: 534 IKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+ L+Q N + F IS + K L+ +L + Q R I I +W
Sbjct: 208 TQNLYQKITNAEFTFPKH----ISMDAKDLLRRILVVDPQKRYSIQQIKRHKW 256
>UniRef50_UPI00003C0E92 Cluster: PREDICTED: similar to CG4290-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG4290-PA
- Apis mellifera
Length = 718
Score = 166 bits (404), Expect = 1e-39
Identities = 86/267 (32%), Positives = 153/267 (57%), Gaps = 15/267 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + +G+G +A V L + K+ +A KII+ + + K RE++++ +L
Sbjct: 17 YDIEGTIGKGNFAVVKLARHRIT----KTEVAIKIIDKTQLDPTNLEKVY-REVEIMKQL 71
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH++ ++ + + K Y+ Y G++ YI + G + E +AR Q+ ++Y H
Sbjct: 72 EHPHIVKLYQVMETKNMIYMVCEYASKGEIFDYIARYGRMGEPRARATFAQILSAVEYCH 131
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFS-RFCVESDNQPVLSETYCGSMSYAAPEILR 197
+AHRD+K EN+LL A NVK++DFGFS RF S + + T+CGS YAAPE+ R
Sbjct: 132 ATGVAHRDLKAENLLLDAQMNVKIADFGFSNRF---SPGERL--STWCGSPPYAAPEVFR 186
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
GK Y D+WSLGVVL+V++ ++PFD + ++ L ++ + ++ R+ +S +C+
Sbjct: 187 GKHYAGPEIDVWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRF----RIPYFMSTDCE 242
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWIA 284
++++ +L +P R++ + W+A
Sbjct: 243 SLIRKMLVLEPTKRYTIPQIKRHRWMA 269
Score = 149 bits (361), Expect = 2e-34
Identities = 80/237 (33%), Positives = 132/237 (55%), Gaps = 11/237 (4%)
Query: 353 LACKVID-TSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A K+ID T P + K + RE+E++ +L HPH+V + + + + ++ Y +G+
Sbjct: 43 VAIKIIDKTQLDPTNLEKVY--REVEIMKQLEHPHIVKLYQVMETKNMIYMVCEYASKGE 100
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
+ +++ + G + E +AR Q+ A++Y H +AHRD+K EN+LL A NVK++DFGF
Sbjct: 101 IFDYIARYGRMGEPRARATFAQILSAVEYCHATGVAHRDLKAENLLLDAQMNVKIADFGF 160
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+ + R T+CGS Y APE+ +G Y DVWSLG+V+YV++ A+PF+
Sbjct: 161 SNRFSPGE----RLSTWCGSPPYAAPEVFRGKHYAGPEIDVWSLGVVLYVLVCGALPFDG 216
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
++ L + + +FR Y +S +C+ LI ML R I I W+A
Sbjct: 217 STLQSLRDRVL--SGRFRIPYF--MSTDCESLIRKMLVLEPTKRYTIPQIKRHRWMA 269
>UniRef50_Q22XQ2 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 786
Score = 166 bits (403), Expect = 2e-39
Identities = 94/278 (33%), Positives = 153/278 (55%), Gaps = 13/278 (4%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
L +G K+ K +GEGA+ KV L + + +A KI+E K V+ + RE+ +
Sbjct: 198 LKEGIKI-KTLGEGAFGKVKLATHILTGEY----VAIKILEKKKIIDVTDVERVQRELHI 252
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
L + HP LI ++ I + T ++ M Y G++ YI + + E +A + +++ G+
Sbjct: 253 LKMIRHPSLIQLYEIIETPTHIFLVMEYCSKGEVFGYIQQKQRLDEVEASKFYQEILYGI 312
Query: 135 QYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPE 194
+YLH+L++ HRD+K EN+LL N N+K+ DFG S +++ L +T CGS YAAPE
Sbjct: 313 EYLHKLQVVHRDLKPENLLLDINHNIKIVDFGLSNMYKKNE----LLKTACGSPCYAAPE 368
Query: 195 ILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSL 254
++ GK Y D+WS GV+LF +L +PF+D RKLY++ + KY S V S
Sbjct: 369 MIEGKKYESPQVDIWSSGVILFALLCGYLPFEDEDTRKLYDKILKGKYGIPSHV----SP 424
Query: 255 ECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTL 292
+ K +++ +L DP R + +W + R T+
Sbjct: 425 DAKDLIEKILTVDPEKRMKFDQIKAHKWFNLYKRSYTI 462
Score = 136 bits (328), Expect = 2e-30
Identities = 81/276 (29%), Positives = 144/276 (52%), Gaps = 16/276 (5%)
Query: 331 ESAF-RVYLAEYRNASKNDKLSILACK-VIDTSTAPRDFVKKFLPREIEMLIKLSHPHLV 388
E AF +V LA + + + IL K +ID + R + RE+ +L + HP L+
Sbjct: 209 EGAFGKVKLATHILTGEYVAIKILEKKKIIDVTDVER------VQRELHILKMIRHPSLI 262
Query: 389 HTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAH 448
+ I + F+ M Y +G++ ++ Q+ + E +A + +++ I+Y+H+L++ H
Sbjct: 263 QLYEIIETPTHIFLVMEYCSKGEVFGYIQQKQRLDEVEASKFYQEILYGIEYLHKLQVVH 322
Query: 449 RDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPK 508
RD+K EN+LL N N+K+ DFG + M K NE+ +T CGS Y APE+++G Y
Sbjct: 323 RDLKPENLLLDINHNIKIVDFGLSNM---YKKNEL-LKTACGSPCYAAPEMIEGKKYESP 378
Query: 509 PTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLML 568
D+WS G++++ +L +PFED+ ++L+ + + S +S + K LI +L
Sbjct: 379 QVDIWSSGVILFALLCGYLPFEDEDTRKLYDKILKGKYGIPSH----VSPDAKDLIEKIL 434
Query: 569 EPNHQNRLKIYDIVNSEWIAMDSRLLEWTPQETLAY 604
+ + R+K I +W + R P + Y
Sbjct: 435 TVDPEKRMKFDQIKAHKWFNLYKRSYTIPPGVIVGY 470
>UniRef50_Q9FJ55 Cluster: Serine/threonine protein kinase; n=14;
Magnoliophyta|Rep: Serine/threonine protein kinase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 483
Score = 165 bits (401), Expect = 3e-39
Identities = 89/278 (32%), Positives = 148/278 (53%), Gaps = 10/278 (3%)
Query: 5 KTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFV 64
K S L+ Y++ + +G G +AKVYL + +S +A K+I+ K K +
Sbjct: 14 KQDQSNHQALILGKYEMGRLLGHGTFAKVYLARNAQSGES----VAIKVIDKEKVLKSGL 69
Query: 65 VKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQAR 124
+ + REI +L R+ HP+++ + + K+K Y M Y + G+L + + K G + E AR
Sbjct: 70 IAHIKREISILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAK-GRLKEEMAR 128
Query: 125 VWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETY 184
+ +QL + + H + HRD+K EN+LL N N+K+SDFG S + Q L T+
Sbjct: 129 KYFQQLISAVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSAVS-DQIRQDGLFHTF 187
Query: 185 CGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRF 244
CG+ +Y APE+L K Y D+WS GV+LFV++ +PF D + +Y+ K YR
Sbjct: 188 CGTPAYVAPEVLARKGYDGAKVDIWSCGVILFVLMAGFLPFHDRNVMAMYK----KIYRG 243
Query: 245 RSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
R +E ++ +LE P R + +++++ W
Sbjct: 244 DFRCPRWFPVEINRLLIRMLETKPERRFTMPDIMETSW 281
Score = 134 bits (325), Expect = 5e-30
Identities = 80/252 (31%), Positives = 140/252 (55%), Gaps = 11/252 (4%)
Query: 335 RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIF 394
+VYLA RNA + ++I KVID + + + REI +L ++ HP++V +
Sbjct: 41 KVYLA--RNAQSGESVAI---KVIDKEKVLKSGLIAHIKREISILRRVRHPNIVQLFEVM 95
Query: 395 QRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCE 454
+ K + M Y++ G+L V +G ++E+ AR + +QL A+ + H + HRD+K E
Sbjct: 96 ATKSKIYFVMEYVKGGELFNKVA-KGRLKEEMARKYFQQLISAVSFCHFRGVYHRDLKPE 154
Query: 455 NVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWS 514
N+LL N N+K+SDFG + + D+ + TFCG+ +Y APE+L Y D+WS
Sbjct: 155 NLLLDENGNLKVSDFGLSAVS-DQIRQDGLFHTFCGTPAYVAPEVLARKGYDGAKVDIWS 213
Query: 515 LGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQN 574
G++++V++ +PF D+++ +++ +I + FR + N RL+ MLE +
Sbjct: 214 CGVILFVLMAGFLPFHDRNVMAMYK-KIYRG-DFRCPRWFPVEIN--RLLIRMLETKPER 269
Query: 575 RLKIYDIVNSEW 586
R + DI+ + W
Sbjct: 270 RFTMPDIMETSW 281
>UniRef50_A2EBI4 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 386
Score = 165 bits (400), Expect = 4e-39
Identities = 92/287 (32%), Positives = 155/287 (54%), Gaps = 14/287 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L VG GA+ V + + + D+ K ACKII +EI ++ +L
Sbjct: 17 YQLQNAVGRGAFGTV---KVAYRPDNGKY-YACKIITKHTIDSMIDKSKFEKEIRIMQQL 72
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+ P ++ + + + YYI GD+ IL+N + E +A+++ +QL + Y+H
Sbjct: 73 HSPRIVQLFDLLKDTMNYYIVTELCTGGDMFQQILQNKKIPEERAKIYAKQLLEAISYIH 132
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+L + HRD+K EN+LL N ++KLSDFGFS+F ++ L+ T CGS YAAPEIL G
Sbjct: 133 KLNVCHRDLKPENILLDNNGDIKLSDFGFSKF-IDG-----LTHTSCGSYVYAAPEILEG 186
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y PK +D+W++GV+++ M+ +P+ +L +Q +Y ++ LS EC +
Sbjct: 187 TDYDPKKSDIWAVGVIIYAMVTGQLPWTKRNQHELSKQIKACQY----KIPQDLSEECLS 242
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKE 305
V+ +L+ +P R SA +L S W+ + + + +LK+ E
Sbjct: 243 VITGILQREPEDRPSADELLKSPWLNNIVTMPSSQILPIISLKKVDE 289
Score = 146 bits (353), Expect = 2e-33
Identities = 77/245 (31%), Positives = 135/245 (55%), Gaps = 12/245 (4%)
Query: 344 ASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIF 403
A + D ACK+I T K +EI ++ +L P +V + + Y+I
Sbjct: 34 AYRPDNGKYYACKIITKHTIDSMIDKSKFEKEIRIMQQLHSPRIVQLFDLLKDTMNYYIV 93
Query: 404 MRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQN 463
GD+ + +LQ + E++A+I+ +QL AI Y+H+L + HRD+K EN+LL N +
Sbjct: 94 TELCTGGDMFQQILQNKKIPEERAKIYAKQLLEAISYIHKLNVCHRDLKPENILLDNNGD 153
Query: 464 VKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVML 523
+KLSDFGF+ K + + T CGS Y APEIL+GT Y PK +D+W++G+++Y M+
Sbjct: 154 IKLSDFGFS------KFIDGLTHTSCGSYVYAAPEILEGTDYDPKKSDIWAVGVIIYAMV 207
Query: 524 NRAMPFEDKHIKQLHQAQINKNWK-FRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIV 582
+P+ + +Q +++K K + + +S+ C +I +L+ ++R +++
Sbjct: 208 TGQLPWTKR-----NQHELSKQIKACQYKIPQDLSEECLSVITGILQREPEDRPSADELL 262
Query: 583 NSEWI 587
S W+
Sbjct: 263 KSPWL 267
>UniRef50_A0E1E2 Cluster: Chromosome undetermined scaffold_73, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_73,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 765
Score = 165 bits (400), Expect = 4e-39
Identities = 87/264 (32%), Positives = 148/264 (56%), Gaps = 14/264 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + K +GEG + KV +K +A KI+E + + ++ + REI +L L
Sbjct: 7 YLIGKTIGEGTFGKVC----HAKHQVLGHDVAVKILEKKRINDELDIERVKREITILQML 62
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP+++ ++ + + T Y+FM Y + G+L YI ++E +A + ++ +QY+H
Sbjct: 63 HHPNVVQLYEMIETDTHIYLFMEYADGGELFDYIDLKKRINEVEACKFLHEIISAIQYIH 122
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+L I HRD+K EN+LLTA N+ + DFG S ++ +T CGS YAAPE+++G
Sbjct: 123 QLRIVHRDLKPENLLLTAQKNILVVDFGLSNTYEDT------LKTACGSPCYAAPEMIQG 176
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
KPY TDLWS GV+L+ ML +PF+D + LY++ + + + +SL+ K
Sbjct: 177 KPYYGLQTDLWSCGVILYAMLCGYLPFEDNNTQVLYKKILTADF----HIPRYVSLDGKD 232
Query: 259 VVKHLLEPDPGLRHSATNVLDSEW 282
++K++L DP R + + +W
Sbjct: 233 LIKNILTVDPTKRFTIEQIKQHKW 256
Score = 134 bits (325), Expect = 5e-30
Identities = 75/234 (32%), Positives = 129/234 (55%), Gaps = 10/234 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ + + + REI +L L HP++V + + + ++FM Y + G+L
Sbjct: 33 VAVKILEKKRINDELDIERVKREITILQMLHHPNVVQLYEMIETDTHIYLFMEYADGGEL 92
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++ + + E +A + ++ AIQY+H+L I HRD+K EN+LLTA +N+ + DFG +
Sbjct: 93 FDYIDLKKRINEVEACKFLHEIISAIQYIHQLRIVHRDLKPENLLLTAQKNILVVDFGLS 152
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
D +T CGS Y APE++QG PY TD+WS G+++Y ML +PFED
Sbjct: 153 NTYED------TLKTACGSPCYAAPEMIQGKPYYGLQTDLWSCGVILYAMLCGYLPFEDN 206
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+ + L++ + ++ RY +S + K LI +L + R I I +W
Sbjct: 207 NTQVLYKKILTADFHI-PRY---VSLDGKDLIKNILTVDPTKRFTIEQIKQHKW 256
>UniRef50_Q65ZH3 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 1592
Score = 164 bits (398), Expect = 8e-39
Identities = 87/274 (31%), Positives = 148/274 (54%), Gaps = 13/274 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
+++TK +G G Y KV L Y K D +A K+I+ + + + REI ++ L
Sbjct: 75 FEITKKLGSGTYGKVSLA-YDHKFDRE---VAVKLIKKSAIESKADLVRIRREIRIMSAL 130
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHP++I ++ +F+ K K + M Y+ G+L Y+ + G + E +AR RQ+ + Y H
Sbjct: 131 NHPNIIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQITSAVLYCH 190
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ +AHRD+K EN+LL N N K++DFG S + + + L T+CGS YA+PEI+ G
Sbjct: 191 KHRVAHRDLKLENILLDQNNNAKIADFGLSNYFADKN----LLTTFCGSPLYASPEIING 246
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
PY D WSLG++L+ ++ SMPFD ++ Q Y F S S+
Sbjct: 247 TPYKGPEVDCWSLGILLYTLVYGSMPFDGRDFNRMVRQIKRGAY-FEPETPSTASM---- 301
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTL 292
+++++L +P R + ++ W+ ++ + +
Sbjct: 302 LIRNMLRVNPERRATIFDIASHWWLNLEENMPVI 335
Score = 154 bits (374), Expect = 6e-36
Identities = 84/243 (34%), Positives = 136/243 (55%), Gaps = 13/243 (5%)
Query: 353 LACKVIDTST--APRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERG 410
+A K+I S + D V+ + REI ++ L+HP+++ + +F+ + K + M Y G
Sbjct: 101 VAVKLIKKSAIESKADLVR--IRREIRIMSALNHPNIIQIYEVFENKDKIILVMEYSSGG 158
Query: 411 DLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFG 470
+L ++V + G++ E +AR RQ+ A+ Y H+ +AHRD+K EN+LL N N K++DFG
Sbjct: 159 ELYDYVSRCGSLPEAEARRIFRQITSAVLYCHKHRVAHRDLKLENILLDQNNNAKIADFG 218
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+ DK L TFCGS Y +PEI+ GTPY D WSLGI++Y ++ +MPF+
Sbjct: 219 LSNYFADKNL----LTTFCGSPLYASPEIINGTPYKGPEVDCWSLGILLYTLVYGSMPFD 274
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
+ ++ + QI + F T S LI ML N + R I+DI + W+ ++
Sbjct: 275 GRDFNRMVR-QIKRGAYFEPETPSTAS----MLIRNMLRVNPERRATIFDIASHWWLNLE 329
Query: 591 SRL 593
+
Sbjct: 330 ENM 332
>UniRef50_Q21017 Cluster: Protein kinase protein 29; n=2;
Caenorhabditis|Rep: Protein kinase protein 29 -
Caenorhabditis elegans
Length = 822
Score = 164 bits (398), Expect = 8e-39
Identities = 86/265 (32%), Positives = 147/265 (55%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + + +G+G +A V + + K+ +A K I+ + ++ ++K L RE+ ++ +
Sbjct: 16 YDVGRAIGKGNFATVRIARHKIA----KTKVAIKSIDVSALDRENLIK-LEREVKIVKVI 70
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HPH++ + I + YI Y +G+L +++ G V+EN AR W + A + YLH
Sbjct: 71 DHPHIVKSYEIMRVDNMLYIVSEYCSSGELYETLIEKGRVAENVARKWFSETASAVAYLH 130
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K EN+LL N N+K+ DFGFS F ++ +Q L T+CGS YAAPE+L G
Sbjct: 131 SQGIVHRDLKAENILLGKNSNIKIIDFGFSNF--QTGDQ--LLNTWCGSPPYAAPELLLG 186
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y D+WS+GV+L++++ PF + KL + ++ +S+EC
Sbjct: 187 NSYDGMKADIWSMGVLLYILVAGGFPFPSDSVNKLKRSVLSGLV----KIPYWVSVECAD 242
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
++ +L +PG R++ NVL W+
Sbjct: 243 FIRKMLVLNPGKRYTIQNVLQHRWM 267
Score = 143 bits (347), Expect = 1e-32
Identities = 86/275 (31%), Positives = 145/275 (52%), Gaps = 22/275 (8%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K ID S R+ + K L RE++++ + HPH+V ++ I + +I Y G+L
Sbjct: 42 VAIKSIDVSALDRENLIK-LEREVKIVKVIDHPHIVKSYEIMRVDNMLYIVSEYCSSGEL 100
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
E ++++G V E+ AR W + A A+ Y+H I HRD+K EN+LL N N+K+ DFGF+
Sbjct: 101 YETLIEKGRVAENVARKWFSETASAVAYLHSQGIVHRDLKAENILLGKNSNIKIIDFGFS 160
Query: 473 RMCV-DKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
D+ LN T+CGS Y APE+L G Y D+WS+G+++Y+++ PF
Sbjct: 161 NFQTGDQLLN-----TWCGSPPYAAPELLLGNSYDGMKADIWSMGVLLYILVAGGFPFPS 215
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAM-- 589
+ +L ++ ++ K +S C I ML N R I +++ W+ +
Sbjct: 216 DSVNKLKRSVLSGLVKIPY----WVSVECADFIRKMLVLNPGKRYTIQNVLQHRWMHIRD 271
Query: 590 ------DSRLLEWTPQETLAYKKAREEKNKLHKTV 618
++LLE P ++ + R++ KL+ T+
Sbjct: 272 DVQKNQAAQLLEAIPSSSI---EIRQQSTKLNPTI 303
>UniRef50_Q6NSM8 Cluster: Serine/threonine-protein kinase QSK
homolog; n=3; Danio rerio|Rep: Serine/threonine-protein
kinase QSK homolog - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 1187
Score = 164 bits (398), Expect = 8e-39
Identities = 80/265 (30%), Positives = 151/265 (56%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y++ + +G+G +A V L + K+ +A KI++ + + + K RE+ ++ L
Sbjct: 59 YEMERTIGKGNFAVVKLATHMIT----KAKVAIKIVDKTQLDDENLKKIF-REVQIMKML 113
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++ + + + Y+ Y G++ +++ +G ++E AR +Q+ + + H
Sbjct: 114 RHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKDARRKFKQIVAAVYFCH 173
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K EN+LL N N+K++DFGFS ++ L +T+CGS YAAPE+ G
Sbjct: 174 CRSIVHRDLKAENLLLDHNLNIKIADFGFSNLF----SRGQLLKTWCGSPPYAAPELFEG 229
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WSLGVVL+V++ ++PFD + ++ L + + K+ R+ +S +C+
Sbjct: 230 KEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKF----RIPFFMSTDCEY 285
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
+++H+L +P R S + ++W+
Sbjct: 286 LIRHMLILEPSRRLSMEQICKNKWM 310
Score = 139 bits (337), Expect = 2e-31
Identities = 73/235 (31%), Positives = 133/235 (56%), Gaps = 9/235 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++D + + +KK RE++++ L HPH++ + + + ++ Y G++
Sbjct: 85 VAIKIVDKTQLDDENLKKIF-REVQIMKMLRHPHIIRLYQVMETERMIYLVTEYASGGEI 143
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ ++ G + E AR +Q+ A+ + H I HRD+K EN+LL N N+K++DFGF+
Sbjct: 144 FDHLVAHGRMAEKDARRKFKQIVAAVYFCHCRSIVHRDLKAENLLLDHNLNIKIADFGFS 203
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ +L +T+CGS Y APE+ +G Y D+WSLG+V+YV++ A+PF+
Sbjct: 204 NLFSRGQL----LKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGS 259
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
++ L +A++ + KFR + +S +C+ LI ML RL + I ++W+
Sbjct: 260 TLQNL-RARV-LSGKFRIPFF--MSTDCEYLIRHMLILEPSRRLSMEQICKNKWM 310
>UniRef50_Q1MTK5 Cluster: Novel protein containing a protein kinase
domain; n=5; Euteleostomi|Rep: Novel protein containing
a protein kinase domain - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 590
Score = 163 bits (397), Expect = 1e-38
Identities = 95/296 (32%), Positives = 149/296 (50%), Gaps = 14/296 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+ + +G+G Y +V D + +A K I K + + + REI+++ L
Sbjct: 43 YEFLETLGKGTYGRV-----KKAMDRSGTAVAIKSIRKEKIRDEQELTHIRREIEIMSSL 97
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HPH+I ++ +F+ K K I M GDL YI + ++E QAR + RQ+ + Y H
Sbjct: 98 SHPHIISIYEVFENKDKIVIVMELASRGDLFDYICDSQPLAETQARHFFRQIVSAVHYCH 157
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K EN+LL N N+K++DFG S D L +TYCGS YA+PEI+ G
Sbjct: 158 RNGIVHRDLKLENILLDCNGNIKIADFGLSNL-YRGDK---LLQTYCGSPLYASPEIVNG 213
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+PY D WSLGV+L+ +++ +MPFD R L +Q YR S+ + L
Sbjct: 214 RPYRGPEVDSWSLGVLLYTLMHGAMPFDGHDHRILVQQISSGSYRKPSKPSDACGL---- 269
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKEDRRKLSDVH 314
++ +L +P R + ++ W+ L L + A A E +S +
Sbjct: 270 -IRWMLMVNPERRATLEDIAGHWWVNWGFELPLLAQSDPATAHPASEPAAVVSQTN 324
Score = 153 bits (372), Expect = 1e-35
Identities = 95/274 (34%), Positives = 141/274 (51%), Gaps = 15/274 (5%)
Query: 314 HKHPPKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLP 373
HKH K + + LE + + RV A R+ + SI K+ D +
Sbjct: 35 HKHNLKHRYEFLETLGKGTYGRVKKAMDRSGTAVAIKSIRKEKIRDEQELTH------IR 88
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
REIE++ LSHPH++ + +F+ + K I M RGDL +++ + E QAR + RQ
Sbjct: 89 REIEIMSSLSHPHIISIYEVFENKDKIVIVMELASRGDLFDYICDSQPLAETQARHFFRQ 148
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+ A+ Y H I HRD+K EN+LL N N+K++DFG + + KL +T+CGS
Sbjct: 149 IVSAVHYCHRNGIVHRDLKLENILLDCNGNIKIADFGLSNLYRGDKL----LQTYCGSPL 204
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y +PEI+ G PY D WSLG+++Y +++ AMPF D H ++ QI+ R
Sbjct: 205 YASPEIVNGRPYRGPEVDSWSLGVLLYTLMHGAMPF-DGHDHRILVQQISSG---SYRKP 260
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
SD C LI ML N + R + DI W+
Sbjct: 261 SKPSDAC-GLIRWMLMVNPERRATLEDIAGHWWV 293
>UniRef50_Q9MAM1 Cluster: T25K16.13; n=9; Brassicaceae|Rep:
T25K16.13 - Arabidopsis thaliana (Mouse-ear cress)
Length = 453
Score = 163 bits (397), Expect = 1e-38
Identities = 93/278 (33%), Positives = 149/278 (53%), Gaps = 9/278 (3%)
Query: 5 KTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFV 64
K TP+ + Y++ + +GEG++AKV + + D A KI++ K + +
Sbjct: 7 KATPASRTRV--GNYEMGRTLGEGSFAKVKYAKNTVTGDQ----AAIKILDREKVFRHKM 60
Query: 65 VKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQAR 124
V+ L REI + + HP+++ + + KTK YI + G+L I + G + E++AR
Sbjct: 61 VEQLKREISTMKLIKHPNVVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEAR 120
Query: 125 VWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETY 184
+ +QL + Y H + HRD+K EN++L AN +K+SDFG S F + +L T
Sbjct: 121 RYFQQLINAVDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLL-HTA 179
Query: 185 CGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRF 244
CG+ +Y APE+L K Y D+WS GV+LFV++ +PFD+ + LY++ K F
Sbjct: 180 CGTPNYVAPEVLSDKGYDGAAADVWSCGVILFVLMAGYLPFDEPNLMTLYKRVRICKAEF 239
Query: 245 RSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
S K V+K +LEP+P R S +L+ EW
Sbjct: 240 --SCPPWFSQGAKRVIKRILEPNPITRISIAELLEDEW 275
Score = 134 bits (324), Expect = 7e-30
Identities = 71/233 (30%), Positives = 127/233 (54%), Gaps = 3/233 (1%)
Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLL 413
A K++D R + + L REI + + HP++V + + K +I + + G+L
Sbjct: 46 AIKILDREKVFRHKMVEQLKREISTMKLIKHPNVVEIIEVMASKTKIYIVLELVNGGELF 105
Query: 414 EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFAR 473
+ + Q+G ++ED+AR + +QL A+ Y H + HRD+K EN++L AN +K+SDFG +
Sbjct: 106 DKIAQQGRLKEDEARRYFQQLINAVDYCHSRGVYHRDLKPENLILDANGVLKVSDFGLSA 165
Query: 474 MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKH 533
+ + + T CG+ +Y APE+L Y DVWS G++++V++ +PF++ +
Sbjct: 166 FSRQVREDGL-LHTACGTPNYVAPEVLSDKGYDGAAADVWSCGVILFVLMAGYLPFDEPN 224
Query: 534 IKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+ L++ + K S KR+I +LEPN R+ I +++ EW
Sbjct: 225 LMTLYKRV--RICKAEFSCPPWFSQGAKRVIKRILEPNPITRISIAELLEDEW 275
>UniRef50_A2X165 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 493
Score = 163 bits (397), Expect = 1e-38
Identities = 93/285 (32%), Positives = 154/285 (54%), Gaps = 10/285 (3%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP 69
E T+L Y++ + +G+G +AKVY Y+ S ++ +A K+I+ K + ++ +
Sbjct: 3 ERRTILMDRYEIGRQLGQGNFAKVY---YARNLTSGQA-VAIKMIDKEKVTRVGLMVQIK 58
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
REI ++ + HP+++ + + K+K Y + Y + G+L I K G SE+ AR + Q
Sbjct: 59 REISIMRLVKHPNILQLFEVMASKSKIYFVLEYAKGGELFKKISK-GKFSEDVARRYFHQ 117
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
L G+ Y H + HRD+K EN+LL N ++K+SDFG S ES L T CG+ +
Sbjct: 118 LISGIDYCHSRGVYHRDLKPENLLLDENESLKVSDFGLSALS-ESKRHDGLLHTTCGTPA 176
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
Y APE+L + Y D+WS GV+LFV+++ +PF DT + ++Y + +Y +
Sbjct: 177 YVAPEVLSRRGYDGAKADIWSCGVILFVLVSGYLPFHDTNLIEMYRKIAKAEY----KCP 232
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNA 294
S E K ++ +L+PDP R S + S W S + L +
Sbjct: 233 RSFSAELKDLLYKILDPDPSTRISIPKIKRSAWYRKSSDVNALKS 277
Score = 126 bits (304), Expect = 2e-27
Identities = 68/239 (28%), Positives = 125/239 (52%), Gaps = 6/239 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID R + + REI ++ + HP+++ + + K + + Y + G+L
Sbjct: 38 VAIKMIDKEKVTRVGLMVQIKREISIMRLVKHPNILQLFEVMASKSKIYFVLEYAKGGEL 97
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ + +G ED AR + QL I Y H + HRD+K EN+LL N+++K+SDFG +
Sbjct: 98 FKKI-SKGKFSEDVARRYFHQLISGIDYCHSRGVYHRDLKPENLLLDENESLKVSDFGLS 156
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ K+ + + T CG+ +Y APE+L Y D+WS G++++V+++ +PF D
Sbjct: 157 ALSESKRHDGL-LHTTCGTPAYVAPEVLSRRGYDGAKADIWSCGVILFVLVSGYLPFHDT 215
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDS 591
++ ++++ +K + S K L+ +L+P+ R+ I I S W S
Sbjct: 216 NLIEMYRKIAKAEYKCPRSF----SAELKDLLYKILDPDPSTRISIPKIKRSAWYRKSS 270
>UniRef50_P92937 Cluster: CBL-interacting serine/threonine-protein
kinase 15; n=69; Magnoliophyta|Rep: CBL-interacting
serine/threonine-protein kinase 15 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 421
Score = 163 bits (397), Expect = 1e-38
Identities = 88/273 (32%), Positives = 154/273 (56%), Gaps = 10/273 (3%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP 69
++ ++L Y++ KF+G+G +AKVY + DS +A K+I+ + K + + +
Sbjct: 3 KKGSVLMLRYEVGKFLGQGTFAKVYHARHLKTGDS----VAIKVIDKERILKVGMTEQIK 58
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
REI + L HP+++ +H + K+K Y M + + G+L + + G + E+ AR + +Q
Sbjct: 59 REISAMRLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARKYFQQ 117
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
L + + H + HRD+K EN+LL + N+K+SDFG S +S Q L T CG+ +
Sbjct: 118 LVRAVDFCHSRGVCHRDLKPENLLLDEHGNLKISDFGLSALS-DSRRQDGLLHTTCGTPA 176
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
Y APE++ Y D+WS GV+LFV+L +PF D+ + +LY +++GK +
Sbjct: 177 YVAPEVISRNGYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELY-KKIGKA---EVKFP 232
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
+ L+ K ++K +L+P+P R S ++ S W
Sbjct: 233 NWLAPGAKRLLKRILDPNPNTRVSTEKIMKSSW 265
Score = 138 bits (335), Expect = 3e-31
Identities = 76/251 (30%), Positives = 135/251 (53%), Gaps = 8/251 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KVID + + + + REI + L HP++V H + + K + M +++ G+L
Sbjct: 38 VAIKVIDKERILKVGMTEQIKREISAMRLLRHPNIVELHEVMATKSKIYFVMEHVKGGEL 97
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
V G ++ED AR + +QL A+ + H + HRD+K EN+LL + N+K+SDFG +
Sbjct: 98 FNKV-STGKLREDVARKYFQQLVRAVDFCHSRGVCHRDLKPENLLLDEHGNLKISDFGLS 156
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ D + + T CG+ +Y APE++ Y DVWS G++++V+L +PF D
Sbjct: 157 ALS-DSRRQDGLLHTTCGTPAYVAPEVISRNGYDGFKADVWSCGVILFVLLAGYLPFRDS 215
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI--AMD 590
++ +L++ K K ++ + ++ KRL+ +L+PN R+ I+ S W +
Sbjct: 216 NLMELYK----KIGKAEVKFPNWLAPGAKRLLKRILDPNPNTRVSTEKIMKSSWFRKGLQ 271
Query: 591 SRLLEWTPQET 601
+ E +ET
Sbjct: 272 EEVKESVEEET 282
>UniRef50_A2ETF3 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 394
Score = 163 bits (396), Expect = 1e-38
Identities = 84/258 (32%), Positives = 144/258 (55%), Gaps = 11/258 (4%)
Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84
+G GA++ V L ++S + ACK+I K ++ EI + +L+HP+++
Sbjct: 20 IGYGAFSIVKLVQHSQSNNF----FACKVISKEKLSSIKRIERFEDEIRIQQQLHHPNVV 75
Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144
++ + + + +YI M + + G+L YI+ G ++E++A+ Q+ G++Y+H++ + H
Sbjct: 76 QIYDLLKDEKNFYIMMEFCQGGELFQYIVDKGKLTEDEAKQILDQILEGIKYIHKMGVVH 135
Query: 145 RDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPK 204
RDIK EN+L+ N NVKLSDFG S++ N L +T CGS YA+PE L G PY
Sbjct: 136 RDIKPENILIDQNGNVKLSDFGLSKYVSLKSN---LVKTPCGSPCYASPECLSGLPYNGY 192
Query: 205 PTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLL 264
+D+WS+GV+L+ + +P+ +L+ Q Y + S LSLEC+ ++ L+
Sbjct: 193 ISDMWSVGVLLYACVCGQLPWTKRSQAELFAQVKSGSY----EIPSSLSLECQDLIMRLM 248
Query: 265 EPDPGLRHSATNVLDSEW 282
+ D R + L EW
Sbjct: 249 DTDTNTRITPEEALKHEW 266
Score = 129 bits (311), Expect = 3e-28
Identities = 78/274 (28%), Positives = 140/274 (51%), Gaps = 12/274 (4%)
Query: 314 HKHPPKRQGDI-LEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFL 372
H P GD +G AF + + S N ACKVI +
Sbjct: 4 HIFTPPSIGDYHFKGEIGYGAFSIVKLVQHSQSNN----FFACKVISKEKLSSIKRIERF 59
Query: 373 PREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTR 432
EI + +L HP++V + + + ++I M + + G+L ++++ +G + ED+A+
Sbjct: 60 EDEIRIQQQLHHPNVVQIYDLLKDEKNFYIMMEFCQGGELFQYIVDKGKLTEDEAKQILD 119
Query: 433 QLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSL 492
Q+ I+Y+H++ + HRDIK EN+L+ N NVKLSDFG ++ V K N ++ T CGS
Sbjct: 120 QILEGIKYIHKMGVVHRDIKPENILIDQNGNVKLSDFGLSKY-VSLKSNLVK--TPCGSP 176
Query: 493 SYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRY 552
Y +PE L G PY +D+WS+G+++Y + +P+ + +L + +++ S
Sbjct: 177 CYASPECLSGLPYNGYISDMWSVGVLLYACVCGQLPWTKRSQAELFAQVKSGSYEIPS-- 234
Query: 553 IDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
++S C+ LI +++ + R+ + + EW
Sbjct: 235 --SLSLECQDLIMRLMDTDTNTRITPEEALKHEW 266
>UniRef50_P54646 Cluster: 5'-AMP-activated protein kinase catalytic
subunit alpha-2; n=79; Eumetazoa|Rep: 5'-AMP-activated
protein kinase catalytic subunit alpha-2 - Homo sapiens
(Human)
Length = 552
Score = 163 bits (396), Expect = 1e-38
Identities = 91/268 (33%), Positives = 143/268 (53%), Gaps = 12/268 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y L +G G + KV + E+ HK +A KI+ K VV + REI L
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLT--GHK--VAVKILNRQKIRSLDVVGKIKREIQNLKLF 71
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++ + T +++ M Y G+L YI K+G V E +AR +Q+ + Y H
Sbjct: 72 RHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCH 131
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ HRD+K ENVLL A+ N K++DFG S + SD + T CGS +YAAPE++ G
Sbjct: 132 RHMVVHRDLKPENVLLDAHMNAKIADFGLSN--MMSDGE--FLRTSCGSPNYAAPEVISG 187
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y D+WS GV+L+ +L ++PFDD + L+++ G + + L+ T
Sbjct: 188 RLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVF----YIPEYLNRSVAT 243
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMD 286
++ H+L+ DP R + ++ + EW D
Sbjct: 244 LLMHMLQVDPLKRATIKDIREHEWFKQD 271
Score = 140 bits (339), Expect = 1e-31
Identities = 74/225 (32%), Positives = 121/225 (53%), Gaps = 9/225 (4%)
Query: 366 DFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQED 425
D V K + REI+ L HPH++ + + +F+ M Y+ G+L +++ + G V+E
Sbjct: 56 DVVGK-IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEM 114
Query: 426 QARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRS 485
+AR +Q+ A+ Y H + HRD+K ENVLL A+ N K++DFG + M D +
Sbjct: 115 EARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF----L 170
Query: 486 ETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKN 545
T CGS +Y APE++ G Y D+WS G+++Y +L +PF+D+H+ L + +I
Sbjct: 171 RTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFK-KIRGG 229
Query: 546 WKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
+ Y++ + L+ ML+ + R I DI EW D
Sbjct: 230 VFYIPEYLNR---SVATLLMHMLQVDPLKRATIKDIREHEWFKQD 271
>UniRef50_UPI0000D56584 Cluster: PREDICTED: similar to CG15072-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG15072-PA - Tribolium castaneum
Length = 1142
Score = 163 bits (395), Expect = 2e-38
Identities = 85/266 (31%), Positives = 144/266 (54%), Gaps = 13/266 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G+G +A V L + ++ +A KII+ ++ + K RE +L +L
Sbjct: 17 YELEKTIGKGNFAVVKLATHIVT----RTKVAIKIIDKTALDEENLTKIF-RETAILKKL 71
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+ ++ + + Y+ Y NG++ +++ G + E++A+ Q+ + Y H
Sbjct: 72 RHPHITRLYQLMETNQTIYMVTEYASNGEIFDHLVAKGRMPEDEAKRIFSQIVSAVSYCH 131
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ HRD+K EN+LL N N+KL+DFGFS E L T+CGS YAAPE+ +G
Sbjct: 132 SQGVVHRDLKAENLLLDHNLNIKLADFGFSNQFTEG----CLLSTWCGSPPYAAPELFQG 187
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y D+WSLGVVL+V++ S+PFD + L + K+ R+ +S +C+
Sbjct: 188 HKYDGPKADIWSLGVVLYVLVCGSLPFDGRTLHDLRNVVIEGKF----RIPYFMSQDCEY 243
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIA 284
+++H+L DP R + + + W+A
Sbjct: 244 LIRHMLVVDPEKRLTMSQIAKHRWLA 269
Score = 148 bits (359), Expect = 4e-34
Identities = 78/236 (33%), Positives = 127/236 (53%), Gaps = 9/236 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID + + + K RE +L KL HPH+ + + + ++ Y G++
Sbjct: 43 VAIKIIDKTALDEENLTKIF-RETAILKKLRHPHITRLYQLMETNQTIYMVTEYASNGEI 101
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ ++ +G + ED+A+ Q+ A+ Y H + HRD+K EN+LL N N+KL+DFGF+
Sbjct: 102 FDHLVAKGRMPEDEAKRIFSQIVSAVSYCHSQGVVHRDLKAENLLLDHNLNIKLADFGFS 161
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ L T+CGS Y APE+ QG Y D+WSLG+V+YV++ ++PF+ +
Sbjct: 162 NQFTEGCL----LSTWCGSPPYAAPELFQGHKYDGPKADIWSLGVVLYVLVCGSLPFDGR 217
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
+ L I KFR Y +S +C+ LI ML + + RL + I W+A
Sbjct: 218 TLHDLRNVVI--EGKFRIPYF--MSQDCEYLIRHMLVVDPEKRLTMSQIAKHRWLA 269
>UniRef50_A7QA52 Cluster: Chromosome undetermined scaffold_69, whole
genome shotgun sequence; n=3; Vitis vinifera|Rep:
Chromosome undetermined scaffold_69, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 743
Score = 163 bits (395), Expect = 2e-38
Identities = 93/314 (29%), Positives = 165/314 (52%), Gaps = 14/314 (4%)
Query: 1 MTDLKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAP 60
M + + ++LL Y+L + +G G +AKVY ++ + ++A K++ K
Sbjct: 346 MAKISQDKLDYSSLLHGKYELGRLLGHGTFAKVY----HARNLRNGESVAMKVVAKDKVI 401
Query: 61 KDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSE 120
K +++ + REI V+ +++HP+++ +H + K+K Y+ M Y G+L S I K G + E
Sbjct: 402 KVGMMEQMKREISVMKKVSHPNIVQLHEVMASKSKIYLAMEYVRGGELFSKIAK-GRLRE 460
Query: 121 NQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDN--QP 178
+ AR + +QL +++ H + HRD+K EN+LL N+K++DFG C SD+ Q
Sbjct: 461 DAARSYFQQLISAVEFCHSRGVFHRDLKPENLLLDEQGNLKVTDFGL---CALSDHLKQD 517
Query: 179 VLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQM 238
L T CG+ +Y APE++ + Y D+WS GV+LFV++ +PF D + +Y+
Sbjct: 518 GLLHTACGTPAYVAPEVIAKRGYDGAKADIWSCGVILFVLMAGFLPFQDDNLIAMYK--- 574
Query: 239 GKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAA 298
K YR + S E + VV LL+P+P R + + + ++ W
Sbjct: 575 -KIYRGDFKCPPWFSPEARRVVCRLLDPNPNTRITISKLKETSWFKKTKPKNVQTTASGV 633
Query: 299 ALKRAKEDRRKLSD 312
A++ E + K+ +
Sbjct: 634 AVEEEMEVKEKVPE 647
Score = 159 bits (386), Expect = 2e-37
Identities = 88/287 (30%), Positives = 153/287 (53%), Gaps = 10/287 (3%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP 69
E ++L K Y++ + +G+G +AKVY + DS +A K+I K +++ +
Sbjct: 11 EARSILFKKYEMGRLLGQGTFAKVYHAKRLGSGDS----VAIKVINKDHVKKQGMMEQIQ 66
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
REI V+ + HP+++ + + KTK + M + + G+L + + K G + E+ AR + +Q
Sbjct: 67 REISVMRLVRHPNVVELKEVMATKTKIFFAMEFVKGGELFAKVTK-GRLKEDSARKYFQQ 125
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
L + + H ++HRD+K EN+LL N N+K+SDFG S + N +L T CG+ +
Sbjct: 126 LVSAIDFCHSRGVSHRDLKPENLLLDENENLKVSDFGLSSLPEQLRNDGLL-HTQCGTPA 184
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
Y APE+LR + Y D WS GV+L+V+L +PF + K+Y + ++ F V
Sbjct: 185 YVAPEVLRKRGYDGAKADTWSCGVILYVLLCGFLPFRAENVMKMYTKVFKAEFEFPPWV- 243
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVE 296
S + K ++ LL DP R + + +++ W R ++E
Sbjct: 244 ---STQAKRLISKLLVADPEKRITISAIMEDPWFQKGFRKPIAFSIE 287
Score = 134 bits (323), Expect = 9e-30
Identities = 79/277 (28%), Positives = 146/277 (52%), Gaps = 13/277 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KVI+ + + + + REI ++ + HP++V + + K F M +++ G+L
Sbjct: 46 VAIKVINKDHVKKQGMMEQIQREISVMRLVRHPNVVELKEVMATKTKIFFAMEFVKGGEL 105
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
V +G ++ED AR + +QL AI + H ++HRD+K EN+LL N+N+K+SDFG +
Sbjct: 106 FAKVT-KGRLKEDSARKYFQQLVSAIDFCHSRGVSHRDLKPENLLLDENENLKVSDFGLS 164
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ ++ N+ T CG+ +Y APE+L+ Y D WS G+++YV+L +PF +
Sbjct: 165 SL-PEQLRNDGLLHTQCGTPAYVAPEVLRKRGYDGAKADTWSCGVILYVLLCGFLPFRAE 223
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSR 592
++ +++ K +K + +S KRLI +L + + R+ I I+ W R
Sbjct: 224 NVMKMY----TKVFKAEFEFPPWVSTQAKRLISKLLVADPEKRITISAIMEDPWFQKGFR 279
Query: 593 LLEWTPQETLAYKKAREEKNKLHKTVETVELPGSSKT 629
+ +A+ +E N+ K + + + +KT
Sbjct: 280 -------KPIAFSIEEQENNEEWKCIHIIWMIFLTKT 309
Score = 131 bits (317), Expect = 5e-29
Identities = 70/271 (25%), Positives = 141/271 (52%), Gaps = 6/271 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KV+ + + + + REI ++ K+SHP++V H + + K ++ M Y+ G+L
Sbjct: 390 VAMKVVAKDKVIKVGMMEQMKREISVMKKVSHPNIVQLHEVMASKSKIYLAMEYVRGGEL 449
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ +G ++ED AR + +QL A+++ H + HRD+K EN+LL N+K++DFG
Sbjct: 450 FSKIA-KGRLREDAARSYFQQLISAVEFCHSRGVFHRDLKPENLLLDEQGNLKVTDFGLC 508
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ K + + T CG+ +Y APE++ Y D+WS G++++V++ +PF+D
Sbjct: 509 ALSDHLKQDGL-LHTACGTPAYVAPEVIAKRGYDGAKADIWSCGVILFVLMAGFLPFQDD 567
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSR 592
++ +++ ++K + S +R++ +L+PN R+ I + + W
Sbjct: 568 NLIAMYKKIYRGDFKCPPWF----SPEARRVVCRLLDPNPNTRITISKLKETSWFKKTKP 623
Query: 593 LLEWTPQETLAYKKAREEKNKLHKTVETVEL 623
T +A ++ E K K+ + + +
Sbjct: 624 KNVQTTASGVAVEEEMEVKEKVPEALNAFHI 654
>UniRef50_Q7R0B9 Cluster: GLP_608_36888_34957; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_608_36888_34957 - Giardia lamblia
ATCC 50803
Length = 643
Score = 163 bits (395), Expect = 2e-38
Identities = 94/265 (35%), Positives = 146/265 (55%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + K +GEG+++KV L + + +A KIIE +K + ++ + REI +L L
Sbjct: 38 YIIGKTIGEGSFSKVRLGTHVLTNER----IALKIIEKSKITEAADIERITREIQILKLL 93
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHP++I ++ I YI Y NG+L YI+ G +SE +A + QL GL +LH
Sbjct: 94 NHPNVIKLYEIVDTPRHVYIVQEYMNNGELFDYIVAKGRLSEKEACRFLCQLLNGLHFLH 153
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K EN+LLTAN ++K+ DFG S ++ +T CGS +YA PE+++G
Sbjct: 154 SRRIVHRDLKPENLLLTANNDIKIIDFGLSNIFHDT-----FMKTCCGSPAYAPPEMIQG 208
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y DLWS G++L+ ML +PF+ + + LY + + ++ S LS K
Sbjct: 209 KLYSGPSADLWSTGIILYAMLCGCLPFEGSTTQSLYIKILSGEF----STPSYLSQGAKD 264
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
V+K LL +P R + ++ WI
Sbjct: 265 VLKALLTVNPDDRVTIEELITYPWI 289
Score = 134 bits (323), Expect = 9e-30
Identities = 83/282 (29%), Positives = 148/282 (52%), Gaps = 16/282 (5%)
Query: 308 RKLSDVHKHPPKRQGDILEGPT-RESAF-RVYLAEYRNASKNDKLSILACKVIDTSTAPR 365
R+ D K KR G+ + G T E +F +V L + N+++++ K+I+ S
Sbjct: 22 REDQDTKKIRVKRVGNYIIGKTIGEGSFSKVRLGTH--VLTNERIAL---KIIEKSKITE 76
Query: 366 DFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQED 425
+ + REI++L L+HP+++ + I +I YM G+L ++++ +G + E
Sbjct: 77 AADIERITREIQILKLLNHPNVIKLYEIVDTPRHVYIVQEYMNNGELFDYIVAKGRLSEK 136
Query: 426 QARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRS 485
+A + QL + ++H I HRD+K EN+LLTAN ++K+ DFG + + D +
Sbjct: 137 EACRFLCQLLNGLHFLHSRRIVHRDLKPENLLLTANNDIKIIDFGLSNIFHDTFM----- 191
Query: 486 ETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKN 545
+T CGS +Y PE++QG Y D+WS GI++Y ML +PFE + L+ ++
Sbjct: 192 KTCCGSPAYAPPEMIQGKLYSGPSADLWSTGIILYAMLCGCLPFEGSTTQSLYIKILSGE 251
Query: 546 WKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ S +S K ++ +L N +R+ I +++ WI
Sbjct: 252 FSTPS----YLSQGAKDVLKALLTVNPDDRVTIEELITYPWI 289
>UniRef50_A0BCL5 Cluster: Chromosome undetermined scaffold_10, whole
genome shotgun sequence; n=5; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_10,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 510
Score = 163 bits (395), Expect = 2e-38
Identities = 85/264 (32%), Positives = 146/264 (55%), Gaps = 12/264 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
+K K +GEG + KV L + + +A KI+E +K V+ + REI +L ++
Sbjct: 22 HKQGKTLGEGTFGKVKLATHILTGEK----VAIKILEKSKIVDASDVERVTREIQILKQV 77
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP+L+ ++ I + + ++ M Y G+L YI++N + + +A + Q+ G++YLH
Sbjct: 78 RHPNLVQLYEIIETPKQLFLVMEYVNGGELFEYIVQNQRIKDVEAIRFYSQILSGIEYLH 137
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+L + HRD+K EN++L + +K+ DFG S F D L +T CGS YAAPE++ G
Sbjct: 138 KLHVVHRDLKPENLILDSRGKLKIIDFGLSNFYKTDD----LLKTACGSPCYAAPEMIAG 193
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS G++LF ML +PF+D +LY++ + +F ++ E K
Sbjct: 194 KRYQGLQVDIWSSGIILFAMLAGYLPFEDPNTNQLYKKIIAGDLKF----PKFITNEAKE 249
Query: 259 VVKHLLEPDPGLRHSATNVLDSEW 282
++K++L DP R++ + W
Sbjct: 250 LIKNILNTDPQKRYTIQEIRKHSW 273
Score = 134 bits (324), Expect = 7e-30
Identities = 79/253 (31%), Positives = 137/253 (54%), Gaps = 15/253 (5%)
Query: 335 RVYLAEYRNASKNDKLSILA-CKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSI 393
+V LA + + + IL K++D S R + REI++L ++ HP+LV + I
Sbjct: 35 KVKLATHILTGEKVAIKILEKSKIVDASDVER------VTREIQILKQVRHPNLVQLYEI 88
Query: 394 FQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKC 453
+ + F+ M Y+ G+L E+++Q +++ +A + Q+ I+Y+H+L + HRD+K
Sbjct: 89 IETPKQLFLVMEYVNGGELFEYIVQNQRIKDVEAIRFYSQILSGIEYLHKLHVVHRDLKP 148
Query: 454 ENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVW 513
EN++L + +K+ DFG + K +++ +T CGS Y APE++ G Y D+W
Sbjct: 149 ENLILDSRGKLKIIDFGLSNF---YKTDDL-LKTACGSPCYAAPEMIAGKRYQGLQVDIW 204
Query: 514 SLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQ 573
S GI+++ ML +PFED + QL++ I + KF I++ K LI +L + Q
Sbjct: 205 SSGIILFAMLAGYLPFEDPNTNQLYKKIIAGDLKFPK----FITNEAKELIKNILNTDPQ 260
Query: 574 NRLKIYDIVNSEW 586
R I +I W
Sbjct: 261 KRYTIQEIRKHSW 273
>UniRef50_Q54DF2 Cluster: Putative uncharacterized protein mrkA;
n=1; Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein mrkA - Dictyostelium discoideum
AX4
Length = 1060
Score = 162 bits (393), Expect = 3e-38
Identities = 82/271 (30%), Positives = 148/271 (54%), Gaps = 12/271 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + K +G G + KV L Y K + K +A KII K + +K + RE+ ++ L
Sbjct: 109 YLVIKTIGRGQFGKVKLG-YHKKIPNEK--VAIKIINKGKLDPE-TLKMVQREVRIMKLL 164
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP++I ++ + + Y+ M Y G+++ +++ +G ++E+QAR + Q+ + Y H
Sbjct: 165 HHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGVLTESQARTFFTQIVSAINYCH 224
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
HRD+K EN+LL N +K+ DFG S +T+CGS +YA+PE++
Sbjct: 225 SKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGS----YLKTFCGSPTYASPELILR 280
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS+GVVLFV++ +PFD +L+++ + Y + S L+ ECK+
Sbjct: 281 KEYNGPSVDVWSMGVVLFVLVTGYLPFDGDNYVELFQKILAGNY----TIPSYLTHECKS 336
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRL 289
++ +L DP R + +++ W++ ++
Sbjct: 337 LISRMLVVDPDKRATMEEIINHPWLSSTKQI 367
Score = 139 bits (336), Expect = 2e-31
Identities = 80/286 (27%), Positives = 146/286 (51%), Gaps = 15/286 (5%)
Query: 311 SDVHKHPPKRQGDILEGPT--RESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFV 368
S +H P G+ L T R +V L Y N+K++I K+I+ + +
Sbjct: 96 SSIHLTPQGTIGNYLVIKTIGRGQFGKVKLG-YHKKIPNEKVAI---KIINKGKLDPETL 151
Query: 369 KKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQAR 428
K + RE+ ++ L HP+++ + + + ++ M Y G++++F++ G + E QAR
Sbjct: 152 K-MVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGVLTESQAR 210
Query: 429 IWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETF 488
+ Q+ AI Y H HRD+K EN+LL N+ +K+ DFG + + +TF
Sbjct: 211 TFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGSY----LKTF 266
Query: 489 CGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKF 548
CGS +Y +PE++ Y DVWS+G+V++V++ +PF+ + +L Q + N+
Sbjct: 267 CGSPTYASPELILRKEYNGPSVDVWSMGVVLFVLVTGYLPFDGDNYVELFQKILAGNYTI 326
Query: 549 RSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLL 594
S ++ CK LI ML + R + +I+N W++ +++
Sbjct: 327 PS----YLTHECKSLISRMLVVDPDKRATMEEIINHPWLSSTKQII 368
>UniRef50_Q8RWC9 Cluster: CBL-interacting serine/threonine-protein
kinase 1; n=15; Magnoliophyta|Rep: CBL-interacting
serine/threonine-protein kinase 1 - Arabidopsis thaliana
(Mouse-ear cress)
Length = 444
Score = 162 bits (393), Expect = 3e-38
Identities = 91/269 (33%), Positives = 147/269 (54%), Gaps = 11/269 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAK-APKDFVVKFLPREIDVLVR 77
Y+L + +GEG + KV +K+ + A KII+ ++ A +F ++ + REI L
Sbjct: 20 YELGRTLGEGNFGKVKF----AKDTVSGHSFAVKIIDKSRIADLNFSLQ-IKREIRTLKM 74
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
L HPH++ +H + KTK + M G+L I+ NG ++E R +QL G+ Y
Sbjct: 75 LKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYC 134
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H + HRD+K ENVLL A ++K++DFG S + +L T CGS +Y APE+L
Sbjct: 135 HSKGVFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLL-HTTCGSPNYVAPEVLA 193
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
+ Y +D+WS GV+L+V+L +PFDD + LY+ K + + LS +
Sbjct: 194 NRGYDGAASDIWSCGVILYVILTGCLPFDDRNLAVLYQ----KICKGDPPIPRWLSPGAR 249
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWIAMD 286
T++K +L+P+P R + + SEW ++
Sbjct: 250 TMIKRMLDPNPVTRITVVGIKASEWFKLE 278
Score = 136 bits (330), Expect = 1e-30
Identities = 77/237 (32%), Positives = 125/237 (52%), Gaps = 5/237 (2%)
Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLL 413
A K+ID S + REI L L HPH+V H + + K + M + G+L
Sbjct: 47 AVKIIDKSRIADLNFSLQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELF 106
Query: 414 EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFAR 473
+ ++ G + E R +QL I Y H + HRD+K ENVLL A ++K++DFG +
Sbjct: 107 DRIVSNGKLTETDGRKMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLSA 166
Query: 474 MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKH 533
+ + ++ T CGS +Y APE+L Y +D+WS G+++YV+L +PF+D++
Sbjct: 167 LPQHFR-DDGLLHTTCGSPNYVAPEVLANRGYDGAASDIWSCGVILYVILTGCLPFDDRN 225
Query: 534 IKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
+ L+Q +I K R+ +S + +I ML+PN R+ + I SEW ++
Sbjct: 226 LAVLYQ-KICKGDPPIPRW---LSPGARTMIKRMLDPNPVTRITVVGIKASEWFKLE 278
>UniRef50_Q9SLZ5 Cluster: OsPK7; n=14; Magnoliophyta|Rep: OsPK7 -
Oryza sativa (Rice)
Length = 520
Score = 161 bits (392), Expect = 4e-38
Identities = 89/270 (32%), Positives = 151/270 (55%), Gaps = 11/270 (4%)
Query: 13 TLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREI 72
T+L K Y+L + +G+G++AKVY + ++ +A K+++ KA K +V + REI
Sbjct: 41 TVLGK-YELGRVLGQGSFAKVYQARHLETDEC----VAIKVLDKEKAVKGGMVHLVKREI 95
Query: 73 DVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLAL 132
+VL R+ HP+++ + + KTK Y M Y G+L S + K G + E+ AR + +QL
Sbjct: 96 NVLRRVRHPNIVQLFEVMASKTKIYFVMEYVRGGELFSRVSK-GRLREDTARRYFQQLVS 154
Query: 133 GLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAA 192
+ + H + HRD+K EN+L+ N ++K+SDFG + + D +L T+CG+ +Y A
Sbjct: 155 AVDFCHARGVFHRDLKPENLLVDENGDLKVSDFGLAAGPDQFDPDGLL-HTFCGTPAYVA 213
Query: 193 PEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASIL 252
PE+LR + Y D+WS GV+LF ++ +PF D + LY K Y R
Sbjct: 214 PEVLRRRGYDGAKADIWSCGVILFALMAGYLPFHDHNIMVLYR----KIYNGEFRCPRWF 269
Query: 253 SLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
S + ++ LL+ +P R + +++S+W
Sbjct: 270 SKDFTRLITRLLDANPKTRITVPEIIESDW 299
Score = 133 bits (322), Expect = 1e-29
Identities = 73/234 (31%), Positives = 131/234 (55%), Gaps = 6/234 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KV+D A + + + REI +L ++ HP++V + + K + M Y+ G+L
Sbjct: 72 VAIKVLDKEKAVKGGMVHLVKREINVLRRVRHPNIVQLFEVMASKTKIYFVMEYVRGGEL 131
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
V +G ++ED AR + +QL A+ + H + HRD+K EN+L+ N ++K+SDFG A
Sbjct: 132 FSRV-SKGRLREDTARRYFQQLVSAVDFCHARGVFHRDLKPENLLVDENGDLKVSDFGLA 190
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
D+ + TFCG+ +Y APE+L+ Y D+WS G++++ ++ +PF D
Sbjct: 191 -AGPDQFDPDGLLHTFCGTPAYVAPEVLRRRGYDGAKADIWSCGVILFALMAGYLPFHDH 249
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+I L++ N ++ R+ S + RLI +L+ N + R+ + +I+ S+W
Sbjct: 250 NIMVLYRKIYNGEFRC-PRW---FSKDFTRLITRLLDANPKTRITVPEIIESDW 299
>UniRef50_A2FHU2 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 387
Score = 161 bits (392), Expect = 4e-38
Identities = 83/238 (34%), Positives = 142/238 (59%), Gaps = 10/238 (4%)
Query: 49 LACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDL 108
+A K++ K + + RE+ + ++L HP + + ++ + YY+ + Y+ENG L
Sbjct: 37 VAIKVLNKTKFQSPDDITRIQRELHLHMKLLHPLISQMFGYYEDDSNYYLIIEYSENGTL 96
Query: 109 LSYILKNGCVSENQARVWTRQLALGLQYLHEL-EIAHRDIKCENVLLTANFNVKLSDFGF 167
L +I KNG + E AR + QL + ++YLH + +IAHRDIK EN+L + +N++L+DFG
Sbjct: 97 LQHINKNGPIIEQLARRYFIQLLIAVEYLHNVKKIAHRDIKLENILFDSFYNIRLTDFGI 156
Query: 168 SRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDD 227
S+ + +NQP T CGS SY APEI++G PY K +D+WSLGVVL+ M+N +PFD
Sbjct: 157 SK---DFENQPEF-HTICGSPSYLAPEIIQGHPYSTK-SDIWSLGVVLYAMVNGKLPFDA 211
Query: 228 TRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAM 285
+ ++L+ + + + F + V S + K ++ +L + R S + + +W ++
Sbjct: 212 SNQKELFHKILKENVTFNANV----SPQLKDLLTKMLNKNQNARISLEQIKEHQWFSI 265
Score = 149 bits (360), Expect = 3e-34
Identities = 82/240 (34%), Positives = 138/240 (57%), Gaps = 14/240 (5%)
Query: 353 LACKVIDTST--APRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERG 410
+A KV++ + +P D + + RE+ + +KL HP + ++ Y++ + Y E G
Sbjct: 37 VAIKVLNKTKFQSPDDITR--IQRELHLHMKLLHPLISQMFGYYEDDSNYYLIIEYSENG 94
Query: 411 DLLEFVLQRGAVQEDQARIWTRQLALAIQYMHEL-EIAHRDIKCENVLLTANQNVKLSDF 469
LL+ + + G + E AR + QL +A++Y+H + +IAHRDIK EN+L + N++L+DF
Sbjct: 95 TLLQHINKNGPIIEQLARRYFIQLLIAVEYLHNVKKIAHRDIKLENILFDSFYNIRLTDF 154
Query: 470 GFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF 529
G ++ D + N+ T CGS SY APEI+QG PY K +D+WSLG+V+Y M+N +PF
Sbjct: 155 GISK---DFE-NQPEFHTICGSPSYLAPEIIQGHPYSTK-SDIWSLGVVLYAMVNGKLPF 209
Query: 530 EDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAM 589
+ + K+L + +N F + +S K L+ ML N R+ + I +W ++
Sbjct: 210 DASNQKELFHKILKENVTFNA----NVSPQLKDLLTKMLNKNQNARISLEQIKEHQWFSI 265
>UniRef50_A4RL66 Cluster: Putative uncharacterized protein; n=4;
Pezizomycotina|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 992
Score = 161 bits (392), Expect = 4e-38
Identities = 87/262 (33%), Positives = 146/262 (55%), Gaps = 20/262 (7%)
Query: 338 LAEYRNASKNDKLSILACKVI-----DTSTAPR------DFVKKF-LPREIEMLIKLSHP 385
+ + + A K D +ACK+I D PR D K+ RE ++ LSHP
Sbjct: 109 MGKVKLARKEDGTEQVACKIIPRVTPDDGHTPRAERERADLSKEVRTAREAAIVTLLSHP 168
Query: 386 HLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELE 445
H+ + + + +++ Y+ G +L++++ G ++E QAR ++RQ+A A+ Y H
Sbjct: 169 HICGLRDVVRTNFHWYMLFEYVNGGQMLDYIISHGKLKEKQARKFSRQIASALDYCHRNS 228
Query: 446 IAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPY 505
I HRD+K EN+L++ ++K+ DFG + + K +TFCGSL + APE+LQ PY
Sbjct: 229 IVHRDLKIENILISKTGDIKIIDFGLSNLFAPKS----HLKTFCGSLYFAAPELLQARPY 284
Query: 506 LPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIG 565
DVWS GIV+YV++ +PF+D+++ LH A+I K Y + +S CK L+G
Sbjct: 285 TGPEVDVWSFGIVLYVLVCGKVPFDDQNMPALH-AKIKKG---VVDYPNWLSSECKHLLG 340
Query: 566 LMLEPNHQNRLKIYDIVNSEWI 587
ML + + R+ + +I++ W+
Sbjct: 341 RMLVTDPKQRITMAEILSHPWM 362
Score = 151 bits (366), Expect = 6e-35
Identities = 90/277 (32%), Positives = 146/277 (52%), Gaps = 24/277 (8%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKII--------ETAKAPKDF--VVKFL 68
+ L K +G G+ KV L KED + +ACKII T +A ++ + K +
Sbjct: 98 WNLGKTIGAGSMGKVKLAR---KEDGTEQ-VACKIIPRVTPDDGHTPRAERERADLSKEV 153
Query: 69 --PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVW 126
RE ++ L+HPH+ + + + +Y+ Y G +L YI+ +G + E QAR +
Sbjct: 154 RTAREAAIVTLLSHPHICGLRDVVRTNFHWYMLFEYVNGGQMLDYIISHGKLKEKQARKF 213
Query: 127 TRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCG 186
+RQ+A L Y H I HRD+K EN+L++ ++K+ DFG S + +T+CG
Sbjct: 214 SRQIASALDYCHRNSIVHRDLKIENILISKTGDIKIIDFGLSNLFAPKSH----LKTFCG 269
Query: 187 SMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRS 246
S+ +AAPE+L+ +PY D+WS G+VL+V++ +PFDD M L+ K +
Sbjct: 270 SLYFAAPELLQARPYTGPEVDVWSFGIVLYVLVCGKVPFDDQNMPALH----AKIKKGVV 325
Query: 247 RVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ LS ECK ++ +L DP R + +L W+
Sbjct: 326 DYPNWLSSECKHLLGRMLVTDPKQRITMAEILSHPWM 362
>UniRef50_A2DBY9 Cluster: CAMK family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 488
Score = 160 bits (389), Expect = 9e-38
Identities = 90/256 (35%), Positives = 145/256 (56%), Gaps = 19/256 (7%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETA---KAPKDFVVKFLPREIDVL 75
Y + K +G G+Y KV L E+ KE K +A KI++ + AP+ + + + REI ++
Sbjct: 11 YYVVKSIGSGSYGKVKLAEH--KETGQK--VAIKIVKKSLFMSAPE--MQEKIQREISIM 64
Query: 76 VRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQ 135
L+HPHL+ + +++ YI + Y +G+L ++++ G S A RQL GL+
Sbjct: 65 RLLDHPHLLKLVDVYESVRHLYIILEYAAHGELFDFLVERGSFSVEMATYLFRQLIYGLE 124
Query: 136 YLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEI 195
+LH +I HRDIK EN+LL A+ NVK++DFGF+R+ E+ + T CGS Y APE+
Sbjct: 125 FLHIHQICHRDIKPENILLDAHDNVKIADFGFARWMPEN-----TAYTACGSPHYTAPEV 179
Query: 196 LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLE 255
+ G PY + D+WS GVV + ++ +PFD+ +RKL + KY+ ++
Sbjct: 180 IIGLPYDGRAADIWSCGVVFYTLMCGRLPFDEPTVRKLLARVRSGKYQMPD-----FPMD 234
Query: 256 CKTVVKHLLEPDPGLR 271
K ++ +L DP R
Sbjct: 235 IKDLITKMLTVDPSKR 250
Score = 139 bits (336), Expect = 2e-31
Identities = 81/249 (32%), Positives = 143/249 (57%), Gaps = 14/249 (5%)
Query: 335 RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIF 394
+V LAE++ + K++I K +AP +++ + REI ++ L HPHL+ ++
Sbjct: 24 KVKLAEHKETGQ--KVAIKIVKKSLFMSAPE--MQEKIQREISIMRLLDHPHLLKLVDVY 79
Query: 395 QRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCE 454
+ +I + Y G+L +F+++RG+ + A RQL ++++H +I HRDIK E
Sbjct: 80 ESVRHLYIILEYAAHGELFDFLVERGSFSVEMATYLFRQLIYGLEFLHIHQICHRDIKPE 139
Query: 455 NVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWS 514
N+LL A+ NVK++DFGFAR + E + T CGS YTAPE++ G PY + D+WS
Sbjct: 140 NILLDAHDNVKIADFGFARW-----MPENTAYTACGSPHYTAPEVIIGLPYDGRAADIWS 194
Query: 515 LGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQN 574
G+V Y ++ +PF++ +++L A++ ++ K++ + + K LI ML +
Sbjct: 195 CGVVFYTLMCGRLPFDEPTVRKL-LARV-RSGKYQ---MPDFPMDIKDLITKMLTVDPSK 249
Query: 575 RLKIYDIVN 583
R+ + +I N
Sbjct: 250 RITLPEIKN 258
>UniRef50_P25323 Cluster: Myosin light chain kinase; n=4;
Dictyostelium discoideum|Rep: Myosin light chain kinase
- Dictyostelium discoideum (Slime mold)
Length = 295
Score = 160 bits (388), Expect = 1e-37
Identities = 95/287 (33%), Positives = 154/287 (53%), Gaps = 13/287 (4%)
Query: 13 TLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREI 72
T + K Y+ + +G GA++ VYL E +K+ K A K+I ++ KD+ K L E+
Sbjct: 2 TEVEKIYEFKEELGRGAFSIVYLGE--NKQT--KQRYAIKVINKSELGKDYE-KNLKMEV 56
Query: 73 DVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLAL 132
D+L ++NHP++I + +F K Y+ M G+L I++ G SE A +++
Sbjct: 57 DILKKVNHPNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVS 116
Query: 133 GLQYLHELEIAHRDIKCENVLLTANFN---VKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
+ YLH L I HRD+K EN+LL + N V ++DFG S+ Q ++ +T CG+ S
Sbjct: 117 AVGYLHGLNIVHRDLKPENLLLKSKENHLEVAIADFGLSKII----GQTLVMQTACGTPS 172
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
Y APE+L Y K D+WS+GV+ +++L PF + +++EQ M Y F
Sbjct: 173 YVAPEVLNATGY-DKEVDMWSIGVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYW 231
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVE 296
+S E K + LL D R +ATN L+ W+ ++ T++ V+
Sbjct: 232 GGISKEAKDFIGKLLVVDVSKRLNATNALNHPWLKSNNSNNTIDTVK 278
Score = 137 bits (331), Expect = 1e-30
Identities = 76/255 (29%), Positives = 136/255 (53%), Gaps = 14/255 (5%)
Query: 336 VYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQ 395
VYL E + + A KVI+ S +D+ K L E+++L K++HP+++ +F
Sbjct: 22 VYLGENKQTKQR-----YAIKVINKSELGKDYEKN-LKMEVDILKKVNHPNIIALKELFD 75
Query: 396 RRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCEN 455
K ++ M + G+L + ++++G+ E A +++ A+ Y+H L I HRD+K EN
Sbjct: 76 TPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNIVHRDLKPEN 135
Query: 456 VLLTANQN---VKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDV 512
+LL + +N V ++DFG +++ + +T CG+ SY APE+L T Y K D+
Sbjct: 136 LLLKSKENHLEVAIADFGLSKIIG----QTLVMQTACGTPSYVAPEVLNATGY-DKEVDM 190
Query: 513 WSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNH 572
WS+G++ Y++L PF + ++ + + N++F Y IS K IG +L +
Sbjct: 191 WSIGVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDV 250
Query: 573 QNRLKIYDIVNSEWI 587
RL + +N W+
Sbjct: 251 SKRLNATNALNHPWL 265
>UniRef50_Q38997 Cluster: SNF1-related protein kinase catalytic
subunit alpha KIN10; n=59; Viridiplantae|Rep:
SNF1-related protein kinase catalytic subunit alpha
KIN10 - Arabidopsis thaliana (Mouse-ear cress)
Length = 535
Score = 160 bits (388), Expect = 1e-37
Identities = 86/264 (32%), Positives = 145/264 (54%), Gaps = 12/264 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
YKL + +G G++ +V + E++ HK +A KI+ K + + + REI +L
Sbjct: 42 YKLGRTLGIGSFGRVKIAEHALT--GHK--VAIKILNRRKIKNMEMEEKVRREIKILRLF 97
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++ + + T Y+ M Y +G+L YI++ G + E++AR + +Q+ G++Y H
Sbjct: 98 MHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCH 157
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ HRD+K EN+LL + NVK++DFG S + +T CGS +YAAPE++ G
Sbjct: 158 RNMVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGH----FLKTSCGSPNYAAPEVISG 213
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS GV+L+ +L ++PFDD + L+++ G Y S LS +
Sbjct: 214 KLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSH----LSPGARD 269
Query: 259 VVKHLLEPDPGLRHSATNVLDSEW 282
++ +L DP R + + W
Sbjct: 270 LIPRMLVVDPMKRVTIPEIRQHPW 293
Score = 140 bits (338), Expect = 1e-31
Identities = 76/260 (29%), Positives = 139/260 (53%), Gaps = 9/260 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ +++ + REI++L HPH++ + + + ++ M Y+ G+L
Sbjct: 68 VAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGEL 127
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++++G +QED+AR + +Q+ ++Y H + HRD+K EN+LL + NVK++DFG +
Sbjct: 128 FDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLS 187
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ D +T CGS +Y APE++ G Y DVWS G+++Y +L +PF+D+
Sbjct: 188 NIMRDGHF----LKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE 243
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI-AMDS 591
+I L + + S +S + LI ML + R+ I +I W A
Sbjct: 244 NIPNLFKKIKGGIYTLPSH----LSPGARDLIPRMLVVDPMKRVTIPEIRQHPWFQAHLP 299
Query: 592 RLLEWTPQETLAYKKAREEK 611
R L P +T+ K +E+
Sbjct: 300 RYLAVPPPDTVQQAKKIDEE 319
>UniRef50_Q0KI87 Cluster: CG11870-PA, isoform A; n=3; Drosophila
melanogaster|Rep: CG11870-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 1427
Score = 159 bits (387), Expect = 2e-37
Identities = 90/285 (31%), Positives = 154/285 (54%), Gaps = 13/285 (4%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
L + + + K +G+G Y KV L +KE + +A K I+ K + + + RE+ +
Sbjct: 66 LRQRFDIIKKLGQGTYGKVQLG--INKETGQE--VAIKTIKKCKIEAEADLVRIRREVQI 121
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
+ ++HP++IH++ +F+ + K + M + G+L Y+ + ++E +AR RQ+A +
Sbjct: 122 MSSVHHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERKVLTEEEARRIFRQVATAV 181
Query: 135 QYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPE 194
Y H+ +I HRD+K EN+LL N K++DFG S D+Q +L T+CGS YA+PE
Sbjct: 182 YYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNV---FDDQRLLG-TFCGSPLYASPE 237
Query: 195 ILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSL 254
I+ G PY D WSLGV+L+ ++ SMPFD + ++L +Q Y + R S
Sbjct: 238 IVEGTPYQGPEVDCWSLGVLLYTLVYGSMPFDGSNFKRLVKQISQGDY-YEPRKPS---- 292
Query: 255 ECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAA 299
T+++ +L P R S + W+ + ++ L+ E A
Sbjct: 293 RASTLIRDMLTVCPRKRASIEQICSHWWVNENDNVSCLDLAEDLA 337
Score = 143 bits (347), Expect = 1e-32
Identities = 83/275 (30%), Positives = 151/275 (54%), Gaps = 16/275 (5%)
Query: 314 HKHPPKRQGDILEGPTRESAFRVYLAEYRNASKNDKL-SILACKVIDTSTAPRDFVKKFL 372
H+ +++ DI++ + + +V L + + + +I CK+ A D V+ +
Sbjct: 62 HRKKLRQRFDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKI----EAEADLVR--I 115
Query: 373 PREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTR 432
RE++++ + HP+++H + +F+ R K + M + G+L +++ +R + E++AR R
Sbjct: 116 RREVQIMSSVHHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERKVLTEEEARRIFR 175
Query: 433 QLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSL 492
Q+A A+ Y H+ +I HRD+K EN+LL N K++DFG + + D++L TFCGS
Sbjct: 176 QVATAVYYCHKHKICHRDLKLENILLDEKGNAKIADFGLSNVFDDQRL----LGTFCGSP 231
Query: 493 SYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRY 552
Y +PEI++GTPY D WSLG+++Y ++ +MPF+ + K+L + QI++ + R
Sbjct: 232 LYASPEIVEGTPYQGPEVDCWSLGVLLYTLVYGSMPFDGSNFKRLVK-QISQGDYYEPRK 290
Query: 553 IDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
LI ML + R I I + W+
Sbjct: 291 ----PSRASTLIRDMLTVCPRKRASIEQICSHWWV 321
>UniRef50_A2EQQ4 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 331
Score = 159 bits (387), Expect = 2e-37
Identities = 99/300 (33%), Positives = 156/300 (52%), Gaps = 14/300 (4%)
Query: 18 GYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVR 77
GY+ +G G++A V L + D K ACK+I ++ +V+ RE++ +
Sbjct: 19 GYRFESIIGRGSFAVVVLVTRIA--DGEK--FACKVISQEYLIENKLVESFKREVENFGK 74
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
L+HP+++ + + Y+ M + GDL YI +G SE QA+ +Q+ + YL
Sbjct: 75 LDHPNILRLIDFLSDEKLIYMIMTLCDAGDLHGYIADHGPFSEYQAKAIFKQIISAVDYL 134
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H L IAHRD+K EN+LL + VKL+DFGFSR V NQ L +T CGS Y APEI+
Sbjct: 135 HSLNIAHRDLKPENILLEKDMTVKLADFGFSRETV--GNQ--LMKTKCGSPIYTAPEIIT 190
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFD-DTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
Y K D+WS+GV+LFVML +P++ T +L+ Q ++ + I +
Sbjct: 191 QPEYDGKMADMWSVGVILFVMLTGKIPWESSTNETQLFFQIRTARFHIPENINPIAA--- 247
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWIAMDSR-LTTLNAVEAAALKRAKEDRRKLSDVHK 315
++ L+ P P +R +A VL WI +R + + V+ + R+ + +HK
Sbjct: 248 -KLIGELMVPQPEMRCTAKEVLTHPWIQDQTRNFCSTHVVQNRRTLLQESGRQSVRVIHK 306
Score = 136 bits (330), Expect = 1e-30
Identities = 84/269 (31%), Positives = 133/269 (49%), Gaps = 11/269 (4%)
Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLL 413
ACKVI + + + RE+E KL HP+++ ++ M + GDL
Sbjct: 47 ACKVISQEYLIENKLVESFKREVENFGKLDHPNILRLIDFLSDEKLIYMIMTLCDAGDLH 106
Query: 414 EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFAR 473
++ G E QA+ +Q+ A+ Y+H L IAHRD+K EN+LL + VKL+DFGF+R
Sbjct: 107 GYIADHGPFSEYQAKAIFKQIISAVDYLHSLNIAHRDLKPENILLEKDMTVKLADFGFSR 166
Query: 474 MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKH 533
V +L +T CGS YTAPEI+ Y K D+WS+G++++VML +P+E
Sbjct: 167 ETVGNQL----MKTKCGSPIYTAPEIITQPEYDGKMADMWSVGVILFVMLTGKIPWESST 222
Query: 534 IKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRL 593
+ QI R + I+ +LIG ++ P + R +++ WI +R
Sbjct: 223 NETQLFFQIR---TARFHIPENINPIAAKLIGELMVPQPEMRCTAKEVLTHPWIQDQTRN 279
Query: 594 LEWT----PQETLAYKKAREEKNKLHKTV 618
T + TL + R+ +HK +
Sbjct: 280 FCSTHVVQNRRTLLQESGRQSVRVIHKRI 308
>UniRef50_Q9H0K1 Cluster: Serine/threonine-protein kinase SNF1-like
kinase 2; n=35; Euteleostomi|Rep:
Serine/threonine-protein kinase SNF1-like kinase 2 -
Homo sapiens (Human)
Length = 926
Score = 159 bits (387), Expect = 2e-37
Identities = 83/269 (30%), Positives = 155/269 (57%), Gaps = 15/269 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFV-VKFLPREIDVLVR 77
Y + +G+G +A V L + K+ +A KII+ K+ D V ++ + RE+ ++
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRIT----KTEVAIKIID--KSQLDAVNLEKIYREVQIMKM 73
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
L+HPH+I ++ + + K+ Y+ Y +NG++ Y+ +G ++E++AR Q+ + Y
Sbjct: 74 LDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYC 133
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H +I HRD+K EN+LL N N+K++DFGF F + L T+CGS YAAPE+
Sbjct: 134 HGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGE----LLATWCGSPPYAAPEVFE 189
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
G+ Y D+WS+GVVL+V++ ++PFD + L ++ + ++ R+ +S +C+
Sbjct: 190 GQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRF----RIPYFMSEDCE 245
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWIAMD 286
+++ +L DP R + + + +W+ ++
Sbjct: 246 HLIRRMLVLDPSKRLTIAQIKEHKWMLIE 274
Score = 147 bits (357), Expect = 7e-34
Identities = 83/269 (30%), Positives = 145/269 (53%), Gaps = 14/269 (5%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID S ++K RE++++ L HPH++ + + + + ++ Y + G++
Sbjct: 46 VAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEI 104
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++ G + E +AR Q+ A+ Y H +I HRD+K EN+LL N N+K++DFGF
Sbjct: 105 FDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFG 164
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
K E+ + T+CGS Y APE+ +G Y D+WS+G+V+YV++ A+PF+
Sbjct: 165 NFF---KSGELLA-TWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGP 220
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSR 592
+ L Q + +FR Y +S++C+ LI ML + RL I I +W+
Sbjct: 221 TLPILRQRVL--EGRFRIPYF--MSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWM----- 271
Query: 593 LLEWTPQETLAYKKAREEKNKLHKTVETV 621
L+E Q + Y + +E + + + E V
Sbjct: 272 LIEVPVQRPVLYPQEQENEPSIGEFNEQV 300
>UniRef50_UPI00006CBF34 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 902
Score = 159 bits (385), Expect = 3e-37
Identities = 84/258 (32%), Positives = 146/258 (56%), Gaps = 12/258 (4%)
Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84
+GEG + KV + + + +A KI+E K V+ + REI +L L H ++I
Sbjct: 41 LGEGTFGKVKVATHILTGEK----VAIKILEKEKIQDVSDVERVSREIHILKLLRHQNII 96
Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144
++ I + + + ++ Y G+L YI+KN V E +A V+ +Q+ G++Y+H+L+I H
Sbjct: 97 QLYEIIETEKQLFLITEYASGGELFDYIVKNTKVQEREASVFFQQIISGVEYIHKLKIVH 156
Query: 145 RDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPK 204
RD+K EN+LL+ N +K+ DFG S +++ L +T CGS YAAPE++ GK Y
Sbjct: 157 RDMKPENLLLSYNKRIKIVDFGLSNTYKKNE----LLKTACGSPCYAAPEMIAGKRYLGL 212
Query: 205 PTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLL 264
D+WS GV+LF ++ +PF+D LY++ + Y ++ +S E + ++K++L
Sbjct: 213 GVDIWSCGVILFALVCGYLPFEDPNTSNLYKKILAGDY----QIPKFVSSEGRDLIKNIL 268
Query: 265 EPDPGLRHSATNVLDSEW 282
DP R + +++ W
Sbjct: 269 TTDPTKRFTISDIRKHPW 286
Score = 126 bits (305), Expect = 1e-27
Identities = 65/213 (30%), Positives = 119/213 (55%), Gaps = 8/213 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
REI +L L H +++ + I + + F+ Y G+L +++++ VQE +A ++ +Q
Sbjct: 82 REIHILKLLRHQNIIQLYEIIETEKQLFLITEYASGGELFDYIVKNTKVQEREASVFFQQ 141
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+ ++Y+H+L+I HRD+K EN+LL+ N+ +K+ DFG + K NE+ +T CGS
Sbjct: 142 IISGVEYIHKLKIVHRDMKPENLLLSYNKRIKIVDFGLSN---TYKKNEL-LKTACGSPC 197
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y APE++ G YL D+WS G++++ ++ +PFED + L++ + +++
Sbjct: 198 YAAPEMIAGKRYLGLGVDIWSCGVILFALVCGYLPFEDPNTSNLYKKILAGDYQIPK--- 254
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+S + LI +L + R I DI W
Sbjct: 255 -FVSSEGRDLIKNILTTDPTKRFTISDIRKHPW 286
>UniRef50_Q9Y7V4 Cluster: Serine threonine protein kinase; n=5;
Fungi/Metazoa group|Rep: Serine threonine protein kinase
- Sclerotinia sclerotiorum
Length = 765
Score = 159 bits (385), Expect = 3e-37
Identities = 87/279 (31%), Positives = 149/279 (53%), Gaps = 13/279 (4%)
Query: 4 LKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDF 63
+++ P ++ Y + + +GEG++ KV L + + +A KII K
Sbjct: 44 MESAPQKKTEQRVGAYSVVRTLGEGSFGKVKLAVHRVTQQQ----VALKIIARRKLISRD 99
Query: 64 VVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQA 123
+ + REI+ L L HPH+I ++++ + + + Y N +L YI+++G + E++A
Sbjct: 100 MAGRVEREIEYLQLLRHPHIIKLYTVIKTPHEIIMVSEYAGN-ELFDYIVQHGKMREDEA 158
Query: 124 RVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSET 183
R + +Q+ ++Y H +I HRD+K EN+LL N NVK++DFG S + + +T
Sbjct: 159 RRFFQQIICAVEYCHRHKIVHRDLKPENLLLDENLNVKIADFGLSNIMTDGN----FLKT 214
Query: 184 YCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYR 243
CGS +YAAPE++ GK Y D+WS GV+L+V+L +PFDD + L+ K R
Sbjct: 215 SCGSPNYAAPEVINGKLYAGPEVDVWSCGVILYVLLVGRLPFDDEHIPSLF----AKIAR 270
Query: 244 FRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
+ V S + E ++K +L +P R + + D W
Sbjct: 271 GQYNVPSYMGREAAALIKKMLAVNPVYRATIAEIRDDPW 309
Score = 139 bits (336), Expect = 2e-31
Identities = 85/257 (33%), Positives = 140/257 (54%), Gaps = 15/257 (5%)
Query: 331 ESAF-RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVH 389
E +F +V LA +R + L I+A + + + RD + + REIE L L HPH++
Sbjct: 67 EGSFGKVKLAVHRVTQQQVALKIIARRKLIS----RDMAGR-VEREIEYLQLLRHPHIIK 121
Query: 390 THSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHR 449
+++ + ++ + Y +L ++++Q G ++ED+AR + +Q+ A++Y H +I HR
Sbjct: 122 LYTVIKTPHEIIMVSEYAGN-ELFDYIVQHGKMREDEARRFFQQIICAVEYCHRHKIVHR 180
Query: 450 DIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKP 509
D+K EN+LL N NVK++DFG + + D +T CGS +Y APE++ G Y
Sbjct: 181 DLKPENLLLDENLNVKIADFGLSNIMTDGNF----LKTSCGSPNYAAPEVINGKLYAGPE 236
Query: 510 TDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLE 569
DVWS G+++YV+L +PF+D+HI L A+I + Y + LI ML
Sbjct: 237 VDVWSCGVILYVLLVGRLPFDDEHIPSLF-AKIARGQYNVPSY---MGREAAALIKKMLA 292
Query: 570 PNHQNRLKIYDIVNSEW 586
N R I +I + W
Sbjct: 293 VNPVYRATIAEIRDDPW 309
>UniRef50_A2EN63 Cluster: CAMK family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 447
Score = 158 bits (384), Expect = 4e-37
Identities = 91/280 (32%), Positives = 153/280 (54%), Gaps = 13/280 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + VGEGA++ V L K+ + ACKI+ ++ + K EI + ++
Sbjct: 17 YTIRGTVGEGAFSVVKLAYNEEKQQYY----ACKIVPKSRLSTHHLEKRFELEIRINQQM 72
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP ++ + I + K YY+ M + NG+L YI+ +G + E++AR R+L L Y+H
Sbjct: 73 HHPGIVGMIDILKDKLNYYVIMEFCPNGELFQYIVDHGRLKEDEARPKIRELLKTLDYIH 132
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ + HRD+K EN+LL +K+SDFG SRF ++S L+ T CGS YA+PE + G
Sbjct: 133 HMGVTHRDLKPENILLDKFGQLKVSDFGLSRF-LDSKG---LASTPCGSPCYASPECISG 188
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
KPY +D+WS GV+L+ M+ +P+ +L+EQ +Y + S LS +C
Sbjct: 189 KPYDGITSDVWSSGVILYAMVTGQLPWTKRNQTQLFEQIRHGEY----TIPSYLSYQCTD 244
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAA 298
++ L+ D R + L +++ D++ L+ V+A+
Sbjct: 245 FIRGLMTVDNKKRLTIPQALKHPFLS-DTQQVELHDVDAS 283
Score = 133 bits (321), Expect = 2e-29
Identities = 90/334 (26%), Positives = 158/334 (47%), Gaps = 16/334 (4%)
Query: 325 LEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSH 384
+ G E AF V Y +K ACK++ S ++K EI + ++ H
Sbjct: 19 IRGTVGEGAFSVVKLAYNE----EKQQYYACKIVPKSRLSTHHLEKRFELEIRINQQMHH 74
Query: 385 PHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHEL 444
P +V I + + Y++ M + G+L ++++ G ++ED+AR R+L + Y+H +
Sbjct: 75 PGIVGMIDILKDKLNYYVIMEFCPNGELFQYIVDHGRLKEDEARPKIRELLKTLDYIHHM 134
Query: 445 EIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTP 504
+ HRD+K EN+LL +K+SDFG +R K L + T CGS Y +PE + G P
Sbjct: 135 GVTHRDLKPENILLDKFGQLKVSDFGLSRFLDSKGL----ASTPCGSPCYASPECISGKP 190
Query: 505 YLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLI 564
Y +DVWS G+++Y M+ +P+ ++ QL + QI Y +S C I
Sbjct: 191 YDGITSDVWSSGVILYAMVTGQLPWTKRNQTQLFE-QIRHGEYTIPSY---LSYQCTDFI 246
Query: 565 GLMLEPNHQNRLKIYDIVNSEWIAMDSRLLEWTPQETLAYKKAREEKNKLHKTVETVELP 624
++ +++ RL I + +++ D++ +E + Y R + + +P
Sbjct: 247 RGLMTVDNKKRLTIPQALKHPFLS-DTQQVELHDVDASQYISLRRVDDFFDIDISCSSIP 305
Query: 625 -GSSKTEH--KVCLPDSLVENNLDGAASTSSYVR 655
G KT++ L N + G +ST +R
Sbjct: 306 TGYRKTDNLSAALLNYEQSSNIIQGKSSTRVRLR 339
>UniRef50_UPI0000D56F77 Cluster: PREDICTED: similar to CG11870-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG11870-PA, isoform A - Tribolium castaneum
Length = 1975
Score = 158 bits (383), Expect = 5e-37
Identities = 80/218 (36%), Positives = 130/218 (59%), Gaps = 8/218 (3%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
+ + K +G+G + KV L +KE + +A K I+ +K + + + REI ++ +
Sbjct: 59 FDIIKKLGQGTFGKVQLG--INKETGQE--VAIKTIKKSKIESEADLVRIRREIQIMSSV 114
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP++IH++ +F+ + K + M Y G+L Y+ + + EN+AR RQ+A Y H
Sbjct: 115 QHPNIIHIYEVFENREKMVLVMEYAAGGELYDYLSERKILDENEARRIFRQIATACYYCH 174
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ +I HRD+K EN+LL N N K++DFG S D+Q +LS T+CGS YA+PEI++G
Sbjct: 175 KHKICHRDLKLENILLDENNNAKIADFGLSNV---FDDQRLLS-TFCGSPLYASPEIVKG 230
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ 236
PY D WSLGV+L+ ++ +MPFD + ++L Q
Sbjct: 231 TPYHGPEVDCWSLGVLLYTLVYGAMPFDGSNFKRLVRQ 268
Score = 152 bits (368), Expect = 3e-35
Identities = 83/235 (35%), Positives = 132/235 (56%), Gaps = 9/235 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K I S + + REI+++ + HP+++H + +F+ R K + M Y G+L
Sbjct: 85 VAIKTIKKSKIESEADLVRIRREIQIMSSVQHPNIIHIYEVFENREKMVLVMEYAAGGEL 144
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++ +R + E++AR RQ+A A Y H+ +I HRD+K EN+LL N N K++DFG +
Sbjct: 145 YDYLSERKILDENEARRIFRQIATACYYCHKHKICHRDLKLENILLDENNNAKIADFGLS 204
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ D++L TFCGS Y +PEI++GTPY D WSLG+++Y ++ AMPF+
Sbjct: 205 NVFDDQRL----LSTFCGSPLYASPEIVKGTPYHGPEVDCWSLGVLLYTLVYGAMPFDGS 260
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ K+L + QI++ F S LI ML N +NR I I W+
Sbjct: 261 NFKRLVR-QISQGDYFEPAKPSPASP----LIREMLTVNPKNRADIEKICTHWWV 310
>UniRef50_A2DHV0 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 364
Score = 157 bits (382), Expect = 7e-37
Identities = 94/284 (33%), Positives = 150/284 (52%), Gaps = 20/284 (7%)
Query: 1 MTDLKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTL-ACKIIETAKA 59
+ D+ T P+ EN Y+ +G+G+++ V + E DS L A KII K
Sbjct: 7 VNDVITPPTLEN------YRFMGPIGKGSFSVVKIVE-----DSVSGQLFAAKIIPKNKL 55
Query: 60 PKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVS 119
+ + EI ++ +LNHP ++ ++ +F+ + YYI M NG+L I++N +S
Sbjct: 56 VASNLSERFETEIRIIRQLNHPGIVQLYDLFKDENNYYIIMELCSNGELYEQIIENERLS 115
Query: 120 ENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPV 179
E +A+ + +Q+ L Y+H L I HRDIK EN+LL + K+SDFG SRF
Sbjct: 116 EIEAKYYMKQILEALCYVHNLGICHRDIKPENILLDEQGHAKISDFGLSRFVTAVG---- 171
Query: 180 LSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMG 239
L+ET CGS YA+PE +RG Y + +D+WS GV+ F ML +P+ +L++Q
Sbjct: 172 LAETPCGSPCYASPECIRGGSYDGRKSDMWSCGVLCFAMLTGQLPWTKRNQSQLFDQIQK 231
Query: 240 KKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
Y S V+ + K ++ L++P+P R + L W+
Sbjct: 232 ADYSIPSYVSEL----GKRFIRGLMDPNPETRLNVEQALSHPWL 271
Score = 132 bits (320), Expect = 2e-29
Identities = 78/271 (28%), Positives = 136/271 (50%), Gaps = 12/271 (4%)
Query: 317 PPKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREI 376
PP + GP + +F V + S + A K+I + + + EI
Sbjct: 13 PPTLENYRFMGPIGKGSFSVVKIVEDSVSGQ----LFAAKIIPKNKLVASNLSERFETEI 68
Query: 377 EMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLAL 436
++ +L+HP +V + +F+ Y+I M G+L E +++ + E +A+ + +Q+
Sbjct: 69 RIIRQLNHPGIVQLYDLFKDENNYYIIMELCSNGELYEQIIENERLSEIEAKYYMKQILE 128
Query: 437 AIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTA 496
A+ Y+H L I HRDIK EN+LL + K+SDFG +R L +ET CGS Y +
Sbjct: 129 ALCYVHNLGICHRDIKPENILLDEQGHAKISDFGLSRFVTAVGL----AETPCGSPCYAS 184
Query: 497 PEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTI 556
PE ++G Y + +D+WS G++ + ML +P+ ++ QL QI K Y+ +
Sbjct: 185 PECIRGGSYDGRKSDMWSCGVLCFAMLTGQLPWTKRNQSQLFD-QIQKADYSIPSYVSEL 243
Query: 557 SDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
KR I +++PN + RL + ++ W+
Sbjct: 244 G---KRFIRGLMDPNPETRLNVEQALSHPWL 271
>UniRef50_A5DM85 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 1410
Score = 157 bits (382), Expect = 7e-37
Identities = 78/218 (35%), Positives = 130/218 (59%), Gaps = 8/218 (3%)
Query: 61 KDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSE 120
KD + + REI ++ + HP+++ ++ +++ K Y+ + Y E G+L Y++K G + E
Sbjct: 106 KDHLPYGIEREIIIMKLIAHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIKRGKLQE 165
Query: 121 NQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVL 180
+A + +Q+ G+ YLH+L I HRD+K EN+LL N N+K++DFG + ++ L
Sbjct: 166 FEAVSYFKQIIHGIGYLHQLNICHRDLKPENLLLDFNKNIKIADFGMAALEIKEK----L 221
Query: 181 SETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGK 240
ET CGS YA+PEI+ GK Y P+D+WS G++LF +L +PFDD +RKL +
Sbjct: 222 LETSCGSPHYASPEIVAGKNYHGAPSDIWSCGIILFALLTGHLPFDDENIRKLLLKVQNG 281
Query: 241 KYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVL 278
K+ + LSLE K ++ +L+ +P R + +L
Sbjct: 282 KF----LMPPDLSLEAKDLITKMLQVNPADRVTIDEIL 315
Score = 145 bits (352), Expect = 3e-33
Identities = 74/218 (33%), Positives = 136/218 (62%), Gaps = 8/218 (3%)
Query: 365 RDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQE 424
+D + + REI ++ ++HP+++ + +++ + ++ + Y+E G+L +++++RG +QE
Sbjct: 106 KDHLPYGIEREIIIMKLIAHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIKRGKLQE 165
Query: 425 DQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIR 484
+A + +Q+ I Y+H+L I HRD+K EN+LL N+N+K++DFG A + + +KL
Sbjct: 166 FEAVSYFKQIIHGIGYLHQLNICHRDLKPENLLLDFNKNIKIADFGMAALEIKEKL---- 221
Query: 485 SETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINK 544
ET CGS Y +PEI+ G Y P+D+WS GI+++ +L +PF+D++I++L +
Sbjct: 222 LETSCGSPHYASPEIVAGKNYHGAPSDIWSCGIILFALLTGHLPFDDENIRKLLLKV--Q 279
Query: 545 NWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIV 582
N KF +S K LI ML+ N +R+ I +I+
Sbjct: 280 NGKFLMP--PDLSLEAKDLITKMLQVNPADRVTIDEIL 315
>UniRef50_O60285 Cluster: NUAK family SNF1-like kinase 1; n=16;
Euteleostomi|Rep: NUAK family SNF1-like kinase 1 - Homo
sapiens (Human)
Length = 661
Score = 157 bits (382), Expect = 7e-37
Identities = 84/265 (31%), Positives = 144/265 (54%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L + +G+G Y KV + E +A K I K + + + REI+++ L
Sbjct: 55 YELQETLGKGTYGKVK----RATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSL 110
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHPH+I ++ +F+ K K I M Y G+L YI + +SE + R + RQ+ + Y H
Sbjct: 111 NHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCH 170
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ + HRD+K EN+LL N N+K++DFG S + D +T+CGS YA+PEI+ G
Sbjct: 171 KNGVVHRDLKLENILLDDNCNIKIADFGLSNL-YQKDK---FLQTFCGSPLYASPEIVNG 226
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+PY D W+LGV+L+ ++ +MPFD + L Q +YR ++ + + +
Sbjct: 227 RPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPS-----DARG 281
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
+++ +L +P R + ++ + W+
Sbjct: 282 LIRWMLMVNPDRRATIEDIANHWWV 306
Score = 147 bits (356), Expect = 9e-34
Identities = 86/274 (31%), Positives = 144/274 (52%), Gaps = 14/274 (5%)
Query: 314 HKHPPKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLP 373
HKH K + ++ E + + +V A R + + ++A K I + +
Sbjct: 47 HKHNLKHRYELQETLGKGTYGKVKRATERFSGR-----VVAIKSIRKDKIKDEQDMVHIR 101
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
REIE++ L+HPH++ + +F+ + K I M Y +G+L +++ +R + E + R + RQ
Sbjct: 102 REIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQ 161
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+ A+ Y H+ + HRD+K EN+LL N N+K++DFG + + K +TFCGS
Sbjct: 162 IVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKF----LQTFCGSPL 217
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y +PEI+ G PY D W+LG+++Y ++ MPF+ K L + QI+ ++R
Sbjct: 218 YASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIR-QISSG-EYRE--- 272
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
T + + LI ML N R I DI N W+
Sbjct: 273 PTQPSDARGLIRWMLMVNPDRRATIEDIANHWWV 306
>UniRef50_A3FPS4 Cluster: OSK4, putative; n=2; Cryptosporidium|Rep:
OSK4, putative - Cryptosporidium parvum Iowa II
Length = 859
Score = 157 bits (381), Expect = 9e-37
Identities = 84/266 (31%), Positives = 143/266 (53%), Gaps = 12/266 (4%)
Query: 17 KGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLV 76
K Y++ + +G G++ KV L + E + + +A KI+ K + + +EI +L
Sbjct: 19 KDYRIGQTLGIGSFGKVKLAIH---EPTGRK-VAVKIMNKVKMKAINMYEKSIKEISILK 74
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
+ HPH+I ++ + + YI M Y G+L YI++ G +SE+++R +Q+ G++Y
Sbjct: 75 SIIHPHIIRLYEVIDTXSDIYIIMEYVTGGELFDYIIQKGRISEDESRRLFQQIISGMEY 134
Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
+ I HRD+K EN+LL N N+K+ DFG S F + D T CGS +YAAPE++
Sbjct: 135 CYINRICHRDLKPENILLDENNNIKIGDFGLSSFIYDGD----FLNTSCGSPNYAAPEVV 190
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
GK Y D+WS GV+L+ +L S+PFDD + L+ + + ++ +
Sbjct: 191 SGKAYTGPEIDVWSCGVILYALLCGSLPFDDENVGNLFRKIRHGAFSLPGHISDL----A 246
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEW 282
K ++ +L DP LR + + + W
Sbjct: 247 KILITKMLTVDPSLRITYKEIRYNTW 272
Score = 133 bits (321), Expect = 2e-29
Identities = 73/242 (30%), Positives = 124/242 (51%), Gaps = 9/242 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
+EI +L + HPH++ + + +I M Y+ G+L ++++Q+G + ED++R +Q
Sbjct: 68 KEISILKSIIHPHIIRLYEVIDTXSDIYIIMEYVTGGELFDYIIQKGRISEDESRRLFQQ 127
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+ ++Y + I HRD+K EN+LL N N+K+ DFG + D T CGS +
Sbjct: 128 IISGMEYCYINRICHRDLKPENILLDENNNIKIGDFGLSSFIYDGDF----LNTSCGSPN 183
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y APE++ G Y DVWS G+++Y +L ++PF+D+++ L + + +
Sbjct: 184 YAAPEVVSGKAYTGPEIDVWSCGVILYALLCGSLPFDDENVGNLFRKIRHGAFSLPGH-- 241
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRL-LEWTPQETLAYKKAREEKN 612
ISD K LI ML + R+ +I + W + LE L+YK +
Sbjct: 242 --ISDLAKILITKMLTVDPSLRITYKEIRYNTWFRYNLPFYLEPQYYHLLSYKLSPRNIK 299
Query: 613 KL 614
KL
Sbjct: 300 KL 301
>UniRef50_UPI000049980F Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 411
Score = 157 bits (380), Expect = 1e-36
Identities = 93/279 (33%), Positives = 152/279 (54%), Gaps = 19/279 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPK-DFVVKFLPREIDVLVR 77
Y + +++G G +A+V E K++ K A KII+ K + K + E ++
Sbjct: 127 YDIGRYLGSGNFARV--REVIEKDNKQK--YAIKIIDRQKMKEIGENEKAVLNEYSIMKN 182
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
L+H ++I +H +F + +Y+ E GDL L GC++E + R+ +Q+ GL+YL
Sbjct: 183 LHHINIIQLHDVFLTQQYFYLVFELVEGGDLFKLTLNKGCLNEKECRIVIKQIFYGLKYL 242
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H+ +I HRDIK EN+LLT+N +K++DFG S+ D + ++ET CG+ Y +PE+L
Sbjct: 243 HQNKIIHRDIKLENILLTSNGIIKITDFGLSK-----DTKKSIAETICGTPMYVSPELLS 297
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPF---DDTR-----MRKLYEQQMGKKYRFRSRVA 249
GK Y K TD+WS GVVL+ + PF ++T R+L++ + Y+F S
Sbjct: 298 GKNYNEK-TDIWSAGVVLYTIACGFQPFRSENETEDGKGGNRELFDLILNGYYQFISPYW 356
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSR 288
+SLE K ++ H+L +P R+ L +I R
Sbjct: 357 DNISLELKDLISHMLIVNPKQRYDIEECLSHPFITSTKR 395
Score = 132 bits (320), Expect = 2e-29
Identities = 80/263 (30%), Positives = 133/263 (50%), Gaps = 15/263 (5%)
Query: 339 AEYRNASKNDKLSILACKVIDTSTAPR-DFVKKFLPREIEMLIKLSHPHLVHTHSIFQRR 397
A R + D A K+ID +K + E ++ L H +++ H +F +
Sbjct: 139 ARVREVIEKDNKQKYAIKIIDRQKMKEIGENEKAVLNEYSIMKNLHHINIIQLHDVFLTQ 198
Query: 398 YKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVL 457
+++ +E GDL + L +G + E + RI +Q+ ++Y+H+ +I HRDIK EN+L
Sbjct: 199 QYFYLVFELVEGGDLFKLTLNKGCLNEKECRIVIKQIFYGLKYLHQNKIIHRDIKLENIL 258
Query: 458 LTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGI 517
LT+N +K++DFG + K + +ET CG+ Y +PE+L G Y K TD+WS G+
Sbjct: 259 LTSNGIIKITDFG-----LSKDTKKSIAETICGTPMYVSPELLSGKNYNEK-TDIWSAGV 312
Query: 518 VVYVMLNRAMPFEDKH--------IKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLE 569
V+Y + PF ++ ++L +N ++F S Y D IS K LI ML
Sbjct: 313 VLYTIACGFQPFRSENETEDGKGGNRELFDLILNGYYQFISPYWDNISLELKDLISHMLI 372
Query: 570 PNHQNRLKIYDIVNSEWIAMDSR 592
N + R I + ++ +I R
Sbjct: 373 VNPKQRYDIEECLSHPFITSTKR 395
>UniRef50_UPI000069E3DA Cluster: UPI000069E3DA related cluster; n=2;
Xenopus tropicalis|Rep: UPI000069E3DA UniRef100 entry -
Xenopus tropicalis
Length = 590
Score = 157 bits (380), Expect = 1e-36
Identities = 87/225 (38%), Positives = 123/225 (54%), Gaps = 8/225 (3%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L + +G G Y KV + E + +A K I+ K + L REI++ L
Sbjct: 58 YELLETLGRGTYGKVK----RATEKATGKMVAVKSIQKDKITDERDRVHLQREIEITALL 113
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
H H+I V +F+ + K I M Y NG+L +I + EN AR + RQ+ + Y H
Sbjct: 114 QHEHIIRVFEVFESRDKIIIVMEYASNGELYDFINNKHQIPENDARRFFRQIVSAVHYCH 173
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ I HRDIK EN+LL N NVKL+DFG S VL ETYCGS YA+PEI++G
Sbjct: 174 KKGIVHRDIKLENILLDDNLNVKLADFGLSN---HFQKHQVL-ETYCGSPLYASPEIVKG 229
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYR 243
PY D W+LGV+L+ ++ MPF+++ + L EQ +YR
Sbjct: 230 LPYQGPEVDCWALGVLLYALVYGIMPFENSNYKSLAEQISRGQYR 274
Score = 155 bits (375), Expect = 5e-36
Identities = 110/341 (32%), Positives = 168/341 (49%), Gaps = 26/341 (7%)
Query: 314 HKHPPKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVI--DTSTAPRDFVKKF 371
HKH K + ++LE R + +V A + K ++A K I D T RD V
Sbjct: 50 HKHSIKHRYELLETLGRGTYGKVKRATEKATGK-----MVAVKSIQKDKITDERDRVH-- 102
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
L REIE+ L H H++ +F+ R K I M Y G+L +F+ + + E+ AR +
Sbjct: 103 LQREIEITALLQHEHIIRVFEVFESRDKIIIVMEYASNGELYDFINNKHQIPENDARRFF 162
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
RQ+ A+ Y H+ I HRDIK EN+LL N NVKL+DFG + ++ ET+CGS
Sbjct: 163 RQIVSAVHYCHKKGIVHRDIKLENILLDDNLNVKLADFGLSNHFQKHQV----LETYCGS 218
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y +PEI++G PY D W+LG+++Y ++ MPFE+ + K L + QI++
Sbjct: 219 PLYASPEIVKGLPYQGPEVDCWALGVLLYALVYGIMPFENSNYKSLAE-QISRGQYREPP 277
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW-------IAMDSRLLEWTPQETLA- 603
++ L+ ML N +R I DI N W + D L LA
Sbjct: 278 HL----SGAFGLVDWMLTVNTSSRATIEDIANHWWVNWGYDTVVCDCELAPECHSPLLAR 333
Query: 604 YKKAREEKNKLHKTVETVELPGSSKTEHKVCLPDSLVENNL 644
Y + + + T+E + + E++VCL S EN++
Sbjct: 334 YIECQNTQGFQMTTMEHQQDELRKEEEYEVCLRKSKKENDI 374
>UniRef50_Q4SUX6 Cluster: Chromosome undetermined SCAF13836, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF13836,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1252
Score = 157 bits (380), Expect = 1e-36
Identities = 72/238 (30%), Positives = 138/238 (57%), Gaps = 9/238 (3%)
Query: 46 KSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTEN 105
++ +A KI++ ++ + + K RE+ ++ L HPH+I ++ + + + Y+ Y
Sbjct: 183 ETQVAIKIVDKSQLDDENLKKIF-REVQIMKLLKHPHIIRLYQVMETERMIYLVTEYASG 241
Query: 106 GDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDF 165
G++ +++ +G ++E AR +Q+ + + H I HRD+K EN+LL N N+K++DF
Sbjct: 242 GEIFDHLVAHGRMAEKDARKKFKQIVAAVYFCHCRNIVHRDLKAENLLLDHNLNIKIADF 301
Query: 166 GFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225
GFS + L +T+CGS YAAPE+ GK Y D+WSLGVVL+V++ ++PF
Sbjct: 302 GFSNMFSKGQ----LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPF 357
Query: 226 DDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
D + ++ L + + K+ R+ +S +C+ +++H+L +P R + + ++W+
Sbjct: 358 DGSTLQNLRARVLSGKF----RIPFFMSTDCEYLIRHMLVLEPSRRLTMEQICKNKWM 411
Score = 142 bits (344), Expect = 3e-32
Identities = 75/235 (31%), Positives = 133/235 (56%), Gaps = 9/235 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++D S + +KK RE++++ L HPH++ + + + ++ Y G++
Sbjct: 186 VAIKIVDKSQLDDENLKKIF-REVQIMKLLKHPHIIRLYQVMETERMIYLVTEYASGGEI 244
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ ++ G + E AR +Q+ A+ + H I HRD+K EN+LL N N+K++DFGF+
Sbjct: 245 FDHLVAHGRMAEKDARKKFKQIVAAVYFCHCRNIVHRDLKAENLLLDHNLNIKIADFGFS 304
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
M +L +T+CGS Y APE+ +G Y D+WSLG+V+YV++ A+PF+
Sbjct: 305 NMFSKGQL----LKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGS 360
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
++ L +A++ + KFR + +S +C+ LI ML RL + I ++W+
Sbjct: 361 TLQNL-RARV-LSGKFRIPFF--MSTDCEYLIRHMLVLEPSRRLTMEQICKNKWM 411
>UniRef50_Q26018 Cluster: Serine/threonine-protein kinase; n=2;
Plasmodium falciparum|Rep: Serine/threonine-protein
kinase - Plasmodium falciparum
Length = 765
Score = 157 bits (380), Expect = 1e-36
Identities = 82/214 (38%), Positives = 126/214 (58%), Gaps = 8/214 (3%)
Query: 23 KFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPH 82
K +G+G + KV L + + +A KI+ + + + +EI++ +NH H
Sbjct: 399 KKIGKGTFGKVCLGIHIYTHE----IVAIKILNKKRLIEIINYDKIIKEIEIHKNINHNH 454
Query: 83 LIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEI 142
+ + ++Q K Y+ + Y ENG+LL+YI N ++EN AR QL ++YLHE++I
Sbjct: 455 ICKFYDVYQNKNNIYMILEYVENGNLLTYIYNNYNINENNARRILYQLINAIEYLHEIKI 514
Query: 143 AHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYC 202
HRD+K EN+LL N NVKL DFG S + L T CGS Y +PEIL G+ Y
Sbjct: 515 VHRDLKPENILLDNNNNVKLIDFGLSTIY----RKNCLLTTSCGSPFYTSPEILLGQKYE 570
Query: 203 PKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ 236
+ TD+WSLG++LF++LN +PF+++ M KL+ Q
Sbjct: 571 AELTDVWSLGIILFLLLNHRLPFNNSDMNKLFTQ 604
Score = 145 bits (352), Expect = 3e-33
Identities = 79/213 (37%), Positives = 121/213 (56%), Gaps = 8/213 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
+EIE+ ++H H+ + ++Q + ++ + Y+E G+LL ++ + E+ AR Q
Sbjct: 442 KEIEIHKNINHNHICKFYDVYQNKNNIYMILEYVENGNLLTYIYNNYNINENNARRILYQ 501
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
L AI+Y+HE++I HRD+K EN+LL N NVKL DFG + + L T CGS
Sbjct: 502 LINAIEYLHEIKIVHRDLKPENILLDNNNNVKLIDFGLSTIYRKNCL----LTTSCGSPF 557
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
YT+PEIL G Y + TDVWSLGI+++++LN +PF + + +L QI K + Y
Sbjct: 558 YTSPEILLGQKYEAELTDVWSLGIILFLLLNHRLPFNNSDMNKLF-TQIIKGILYFQPY- 615
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+S N K L+ ML N + R + I N W
Sbjct: 616 --VSKNAKHLLQNMLNVNFKKRFTMNKIKNHIW 646
>UniRef50_Q1HGK2 Cluster: SNF1; n=3; Pezizomycotina|Rep: SNF1 -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 803
Score = 157 bits (380), Expect = 1e-36
Identities = 87/268 (32%), Positives = 145/268 (54%), Gaps = 13/268 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+++K +GEG++ KV L + K +A KII + + + REI+ L L
Sbjct: 130 YEISKTLGEGSFGKVKLAVHKGT----KQMVALKIISRKRLASTDMAGRVEREIEYLQLL 185
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++++ + + + + Y G+L +I+ NG +SE++AR + +Q+ ++Y H
Sbjct: 186 RHPHIIKLYTVIKTDNEIIMVLEYA-GGELFDHIVTNGRLSEDEARRFFQQMLCAVEYCH 244
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+I HRD+K EN+LL N NVK++DFG S + + +T CGS +YAAPE++ G
Sbjct: 245 RHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGN----FLKTSCGSPNYAAPEVISG 300
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS GV+L+V+L +PFDD + L+ K R V +S
Sbjct: 301 KLYAGSEVDVWSCGVILYVLLVGRLPFDDDHIPTLF----SKIARGTYVVPHWMSPGAAA 356
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMD 286
++K +L +P R + T + W +
Sbjct: 357 LIKKMLVVNPVNRATITEIRQDPWFTTE 384
Score = 137 bits (331), Expect = 1e-30
Identities = 77/239 (32%), Positives = 126/239 (52%), Gaps = 9/239 (3%)
Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
++A K+I + + REIE L L HPH++ +++ + + + + Y G+
Sbjct: 155 MVALKIISRKRLASTDMAGRVEREIEYLQLLRHPHIIKLYTVIKTDNEIIMVLEYAG-GE 213
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
L + ++ G + ED+AR + +Q+ A++Y H +I HRD+K EN+LL N NVK++DFG
Sbjct: 214 LFDHIVTNGRLSEDEARRFFQQMLCAVEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGL 273
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+ + D +T CGS +Y APE++ G Y DVWS G+++YV+L +PF+D
Sbjct: 274 SNIMTDGNF----LKTSCGSPNYAAPEVISGKLYAGSEVDVWSCGVILYVLLVGRLPFDD 329
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
HI L ++I + + +S LI ML N NR I +I W +
Sbjct: 330 DHIPTLF-SKIARGTYVVPHW---MSPGAAALIKKMLVVNPVNRATITEIRQDPWFTTE 384
>UniRef50_A5E3E1 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 1625
Score = 157 bits (380), Expect = 1e-36
Identities = 75/211 (35%), Positives = 126/211 (59%), Gaps = 8/211 (3%)
Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127
+ REI ++ ++HP+++ ++ +++ K Y+ + Y E G+L Y++K G + E++A +
Sbjct: 156 IEREIIIMKLISHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIKKGRLHESEAVNYF 215
Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187
+Q+ G+ YLH+ I HRD+K EN+LL N N+K++DFG + ++ L ET CGS
Sbjct: 216 KQIINGINYLHQFNICHRDLKPENLLLDFNKNIKIADFGMAALEIKER----LLETSCGS 271
Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSR 247
YA+PEI+ GK Y P+D+WS G++LF +L +PFDD +RKL + K+
Sbjct: 272 PHYASPEIVAGKTYHGAPSDIWSCGIILFALLTGHLPFDDENIRKLLLKVQSGKFIMPHE 331
Query: 248 VASILSLECKTVVKHLLEPDPGLRHSATNVL 278
LS E K ++ +L+ +P R S +L
Sbjct: 332 ----LSWEAKDLISKMLKVNPAERISMAGIL 358
Score = 140 bits (338), Expect = 1e-31
Identities = 68/212 (32%), Positives = 131/212 (61%), Gaps = 8/212 (3%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ REI ++ +SHP+++ + +++ + ++ + Y+E G+L ++++++G + E +A +
Sbjct: 156 IEREIIIMKLISHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIKKGRLHESEAVNYF 215
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
+Q+ I Y+H+ I HRD+K EN+LL N+N+K++DFG A + + ++L ET CGS
Sbjct: 216 KQIINGINYLHQFNICHRDLKPENLLLDFNKNIKIADFGMAALEIKERL----LETSCGS 271
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y +PEI+ G Y P+D+WS GI+++ +L +PF+D++I++L ++ KF
Sbjct: 272 PHYASPEIVAGKTYHGAPSDIWSCGIILFALLTGHLPFDDENIRKLLLKV--QSGKFIMP 329
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKIYDIVN 583
+ +S K LI ML+ N R+ + I++
Sbjct: 330 H--ELSWEAKDLISKMLKVNPAERISMAGILS 359
>UniRef50_A3LVN1 Cluster: Predicted protein; n=1; Pichia
stipitis|Rep: Predicted protein - Pichia stipitis
(Yeast)
Length = 1465
Score = 157 bits (380), Expect = 1e-36
Identities = 77/211 (36%), Positives = 125/211 (59%), Gaps = 8/211 (3%)
Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127
+ REI ++ ++HP+++ ++ +++ K Y+ + Y E G+L Y++K G + E +A +
Sbjct: 123 IEREIIIMKLISHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIKRGKLQEFEAINYF 182
Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187
+Q+ G+ YLH+ I HRD+K EN+LL N N+K++DFG + V L ET CGS
Sbjct: 183 KQIIHGIGYLHQFNICHRDLKPENLLLDFNKNIKIADFGMAALEVREK----LLETSCGS 238
Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSR 247
YA+PEI+ GK Y P+D+WS G++LF +L +PFDD +RKL + K+
Sbjct: 239 PHYASPEIVAGKNYHGAPSDIWSCGIILFALLTGHLPFDDENIRKLLLKVQNGKF----I 294
Query: 248 VASILSLECKTVVKHLLEPDPGLRHSATNVL 278
+ LS E K ++ +L DP R + N+L
Sbjct: 295 MPHDLSWEAKDLISKMLRVDPSERITIDNIL 325
Score = 142 bits (345), Expect = 2e-32
Identities = 73/211 (34%), Positives = 131/211 (62%), Gaps = 8/211 (3%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ REI ++ +SHP+++ + +++ + ++ + Y+E G+L +++++RG +QE +A +
Sbjct: 123 IEREIIIMKLISHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIKRGKLQEFEAINYF 182
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
+Q+ I Y+H+ I HRD+K EN+LL N+N+K++DFG A + V +KL ET CGS
Sbjct: 183 KQIIHGIGYLHQFNICHRDLKPENLLLDFNKNIKIADFGMAALEVREKL----LETSCGS 238
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y +PEI+ G Y P+D+WS GI+++ +L +PF+D++I++L +N KF
Sbjct: 239 PHYASPEIVAGKNYHGAPSDIWSCGIILFALLTGHLPFDDENIRKLLLKV--QNGKFIMP 296
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKIYDIV 582
+ +S K LI ML + R+ I +I+
Sbjct: 297 H--DLSWEAKDLISKMLRVDPSERITIDNIL 325
>UniRef50_UPI0001560DD3 Cluster: PREDICTED: similar to
MAP/microtubule affinity-regulating kinase 2; n=5; Equus
caballus|Rep: PREDICTED: similar to MAP/microtubule
affinity-regulating kinase 2 - Equus caballus
Length = 620
Score = 156 bits (379), Expect = 2e-36
Identities = 90/267 (33%), Positives = 139/267 (52%), Gaps = 14/267 (5%)
Query: 17 KGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLV 76
+ Y+L + +GEG++ V L + + +A KII+ K K L E L
Sbjct: 62 RDYQLRRTLGEGSFGIVKLALHVPSG----TEVAVKIIQK-KEQSAATAKRLVCETQGLA 116
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
RL HPH++ + + + K +I Y G+LL +++++G ++E +AR W RQL LQY
Sbjct: 117 RLRHPHILRLVEVMESKETLFIISEYVRGGNLLDHLMEHGPLTEEEARGWFRQLVSALQY 176
Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
H + HRD+K ENVLL + KL+DFG FC P+ T+CG+ Y APE++
Sbjct: 177 CHRRGVIHRDLKPENVLLDPAGSAKLADFG---FCSLDPGGPL--STFCGTPGYMAPEVM 231
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
R +PY P D+WSLGV+L ML S+PF + + Y ++S +C
Sbjct: 232 RLQPYDGPPADVWSLGVLLHAMLAGSLPFWGEDFEAIQRSTLRGAY----SPPRLVSCQC 287
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWI 283
+++ LL DPG R + V+ W+
Sbjct: 288 AQLLRGLLTLDPGKRKTLEEVMGDPWV 314
Score = 132 bits (320), Expect = 2e-29
Identities = 72/235 (30%), Positives = 125/235 (53%), Gaps = 10/235 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I K+ L E + L +L HPH++ + + + FI Y+ G+L
Sbjct: 90 VAVKIIQKKEQSAATAKR-LVCETQGLARLRHPHILRLVEVMESKETLFIISEYVRGGNL 148
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
L+ +++ G + E++AR W RQL A+QY H + HRD+K ENVLL + KL+DFGF
Sbjct: 149 LDHLMEHGPLTEEEARGWFRQLVSALQYCHRRGVIHRDLKPENVLLDPAGSAKLADFGFC 208
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ L+ TFCG+ Y APE+++ PY P DVWSLG++++ ML ++PF +
Sbjct: 209 SLDPGGPLS-----TFCGTPGYMAPEVMRLQPYDGPPADVWSLGVLLHAMLAGSLPFWGE 263
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ + ++ + + +S C +L+ +L + R + +++ W+
Sbjct: 264 DFEAIQRSTLRGAYSPPR----LVSCQCAQLLRGLLTLDPGKRKTLEEVMGDPWV 314
>UniRef50_A2E7E2 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 311
Score = 156 bits (379), Expect = 2e-36
Identities = 89/273 (32%), Positives = 152/273 (55%), Gaps = 15/273 (5%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
L YK+ K +G+G +++VYL E S +D K +A K+I +K +K + +EI +
Sbjct: 5 LKSKYKILKEIGQGGFSRVYLGE--SLKDQKK--VAIKVI--SKTNDLCEMKDIQKEIKI 58
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
+ P+++ + +++ K + I M Y G+L +I++ G +E +A +Q+ +GL
Sbjct: 59 QKQFESPYIVTFYDMYETKKEIVIVMEYVNGGELFDHIVQKGSFTEQEAANIIQQVLIGL 118
Query: 135 QYLHELEIAHRDIKCENVLL----TANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSY 190
+ LHE ++ HRD+K EN+LL N VK++DFG S S++ + +CG+ Y
Sbjct: 119 KVLHEKKVIHRDLKPENLLLFIDEKGNTTVKIADFGLSGLIDNSEDM----KRFCGTEGY 174
Query: 191 AAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVAS 250
AAPEI++ PY D+WSLGV+++ +++ PFD +LYEQ + Y F S
Sbjct: 175 AAPEIMKNVPY-DWSVDVWSLGVIVYNLVSGYKPFDSDDDYELYEQVVAADYEFFSPEFD 233
Query: 251 ILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+S ECK + H+L+ R++ +L+ WI
Sbjct: 234 CISDECKDFITHMLQAKAKDRYTVEMLLEHPWI 266
Score = 134 bits (325), Expect = 5e-30
Identities = 84/288 (29%), Positives = 156/288 (54%), Gaps = 18/288 (6%)
Query: 335 RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIF 394
RVYL E S D+ + A KVI + + K + +EI++ + P++V + ++
Sbjct: 22 RVYLGE----SLKDQKKV-AIKVISKTNDLCEM--KDIQKEIKIQKQFESPYIVTFYDMY 74
Query: 395 QRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCE 454
+ + + I M Y+ G+L + ++Q+G+ E +A +Q+ + ++ +HE ++ HRD+K E
Sbjct: 75 ETKKEIVIVMEYVNGGELFDHIVQKGSFTEQEAANIIQQVLIGLKVLHEKKVIHRDLKPE 134
Query: 455 NVLL----TANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPT 510
N+LL N VK++DFG + + +D N + FCG+ Y APEI++ PY
Sbjct: 135 NLLLFIDEKGNTTVKIADFGLSGL-ID---NSEDMKRFCGTEGYAAPEIMKNVPY-DWSV 189
Query: 511 DVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEP 570
DVWSLG++VY +++ PF+ +L++ + +++F S D ISD CK I ML+
Sbjct: 190 DVWSLGVIVYNLVSGYKPFDSDDDYELYEQVVAADYEFFSPEFDCISDECKDFITHMLQA 249
Query: 571 NHQNRLKIYDIVNSEWIAMDSRLLEWTPQETLAYKKAREEKNKLHKTV 618
++R + ++ WI ++ +E T + ++ + K KL + +
Sbjct: 250 KAKDRYTVEMLLEHPWIKGNAPKVEIT--DLQSHLREFNAKRKLRRAL 295
>UniRef50_O22932 Cluster: CBL-interacting serine/threonine-protein
kinase 11; n=10; core eudicotyledons|Rep:
CBL-interacting serine/threonine-protein kinase 11 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 435
Score = 156 bits (379), Expect = 2e-36
Identities = 89/274 (32%), Positives = 149/274 (54%), Gaps = 10/274 (3%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKA-PKDFVVKFL 68
+ N L Y+L K +G GA+AKV+ +++ ++A KI+ K + +
Sbjct: 12 DNNDALFGKYELGKLLGCGAFAKVF----HARDRRTGQSVAVKILNKKKLLTNPALANNI 67
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTR 128
REI ++ RL+HP+++ +H + K+K + M + + G+L + I K+G +SE+ +R + +
Sbjct: 68 KREISIMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQ 127
Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
QL + Y H + HRD+K EN+L+ N N+K+SDFG S + L T CG+
Sbjct: 128 QLISAVGYCHARGVYHRDLKPENLLIDENGNLKVSDFGLSAL-TDQIRPDGLLHTLCGTP 186
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
+Y APEIL K Y D+WS G+VLFV++ +PF+D + +Y++ +YRF
Sbjct: 187 AYVAPEILSKKGYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRF---- 242
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
+S + K V LL+ +P R + +L W
Sbjct: 243 PRWMSPDLKRFVSRLLDINPETRITIDEILKDPW 276
Score = 143 bits (346), Expect = 2e-32
Identities = 80/252 (31%), Positives = 140/252 (55%), Gaps = 9/252 (3%)
Query: 335 RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIF 394
+V+ A R ++ + IL K + T+ A + +K REI ++ +LSHP++V H +
Sbjct: 34 KVFHARDRRTGQSVAVKILNKKKLLTNPALANNIK----REISIMRRLSHPNIVKLHEVM 89
Query: 395 QRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCE 454
+ K F M +++ G+L + + G + ED +R + +QL A+ Y H + HRD+K E
Sbjct: 90 ATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARGVYHRDLKPE 149
Query: 455 NVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWS 514
N+L+ N N+K+SDFG + + D+ + T CG+ +Y APEIL Y DVWS
Sbjct: 150 NLLIDENGNLKVSDFGLSAL-TDQIRPDGLLHTLCGTPAYVAPEILSKKGYEGAKVDVWS 208
Query: 515 LGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQN 574
GIV++V++ +PF D ++ +++ K +K R+ +S + KR + +L+ N +
Sbjct: 209 CGIVLFVLVAGYLPFNDPNVMNMYK----KIYKGEYRFPRWMSPDLKRFVSRLLDINPET 264
Query: 575 RLKIYDIVNSEW 586
R+ I +I+ W
Sbjct: 265 RITIDEILKDPW 276
>UniRef50_Q8TDC3 Cluster: BR serine/threonine-protein kinase 1;
n=33; Euteleostomi|Rep: BR serine/threonine-protein
kinase 1 - Homo sapiens (Human)
Length = 794
Score = 156 bits (379), Expect = 2e-36
Identities = 82/264 (31%), Positives = 143/264 (54%), Gaps = 13/264 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G+G V L + +A KI+ K + ++K + REI +L +
Sbjct: 50 YRLEKTLGKGQTGLVKLGVHCITGQK----VAIKIVNREKLSESVLMK-VEREIAILKLI 104
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH++ +H +++ K Y+ + + G+L Y++K G ++ +AR + RQ+ L + H
Sbjct: 105 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCH 164
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K EN+LL N++++DFG + V L ET CGS YA PE+++G
Sbjct: 165 SYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDS----LLETSCGSPHYACPEVIKG 220
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y + D+WS GV+LF +L ++PFDD +R+L E K R + + +C++
Sbjct: 221 EKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLE----KVKRGVFHMPHFIPPDCQS 276
Query: 259 VVKHLLEPDPGLRHSATNVLDSEW 282
+++ ++E +P R S + W
Sbjct: 277 LLRGMIEVEPEKRLSLEQIQKHPW 300
Score = 138 bits (335), Expect = 3e-31
Identities = 68/234 (29%), Positives = 130/234 (55%), Gaps = 9/234 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ + K + REI +L + HPH++ H +++ + ++ + ++ G+L
Sbjct: 76 VAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGEL 134
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++++G + +AR + RQ+ A+ + H I HRD+K EN+LL N++++DFG A
Sbjct: 135 FDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMA 194
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ V L ET CGS Y PE+++G Y + D+WS G++++ +L A+PF+D
Sbjct: 195 SLQVGDSL----LETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDD 250
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+++QL + K F + I +C+ L+ M+E + RL + I W
Sbjct: 251 NLRQLLEKV--KRGVFHMPHF--IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 300
>UniRef50_UPI0000E21E7B Cluster: PREDICTED: maternal embryonic
leucine zipper kinase isoform 12; n=3; Eutheria|Rep:
PREDICTED: maternal embryonic leucine zipper kinase
isoform 12 - Pan troglodytes
Length = 622
Score = 156 bits (378), Expect = 2e-36
Identities = 90/273 (32%), Positives = 146/273 (53%), Gaps = 14/273 (5%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
L K Y+L + +G G +AKV L + + T+A KI++ D + + EI+
Sbjct: 7 LLKYYELHETIGTGGFAKVKLACHILTGE----TVAIKIMDKNTLGSD--LPRIKTEIEA 60
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
L L H H+ ++ + + K ++ + Y G+L YI+ +SE + RV RQ+ +
Sbjct: 61 LKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAV 120
Query: 135 QYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVE-SDNQPVLSETYCGSMSYAAP 193
Y+H AHRD+K EN+L +KL DFG C + N+ +T CGS++YAAP
Sbjct: 121 AYVHSQGYAHRDLKPENLLFDEYHKLKLIDFG---LCAKPKGNKDYHLQTCCGSLAYAAP 177
Query: 194 EILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILS 253
E+++GK Y D+WS+G++L+V++ +PFDD + LY++ M KY V LS
Sbjct: 178 ELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKY----DVPKWLS 233
Query: 254 LECKTVVKHLLEPDPGLRHSATNVLDSEWIAMD 286
+++ +L+ DP R S N+L+ WI D
Sbjct: 234 PSSILLLQQMLQVDPKKRISMKNLLNHPWIMQD 266
Score = 145 bits (352), Expect = 3e-33
Identities = 78/254 (30%), Positives = 138/254 (54%), Gaps = 11/254 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++D +T D + + EIE L L H H+ + + + K F+ + Y G+L
Sbjct: 37 VAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGEL 94
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++ + + E++ R+ RQ+ A+ Y+H AHRD+K EN+L +KL DFG
Sbjct: 95 FDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFG-- 152
Query: 473 RMCVDKKLN-EIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+C K N + +T CGSL+Y APE++QG YL DVWS+GI++YV++ +PF+D
Sbjct: 153 -LCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDD 211
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDS 591
++ L++ K + + +S + L+ ML+ + + R+ + +++N WI D
Sbjct: 212 DNVMALYK----KIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDY 267
Query: 592 RL-LEWTPQETLAY 604
+EW + Y
Sbjct: 268 NYPVEWQSKNPWQY 281
>UniRef50_A2ENP4 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 357
Score = 156 bits (378), Expect = 2e-36
Identities = 79/265 (29%), Positives = 143/265 (53%), Gaps = 12/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y++ K + G+++ V L E + ACKI+ ++ ++ +EI L
Sbjct: 27 YRVVKVINHGSFSVVCLVENIRTLQQY----ACKIVSRQTLRENETIQHFEQEIRFHQSL 82
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
H ++ ++ I + ++ M Y NG+L I K + + Q R + QL + Y+H
Sbjct: 83 KHKNICQLYEIVYEQDFIFLIMEYCANGELFELITKRARLPQYQIRKYFSQLVAAVNYIH 142
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
IAHRD+K EN+ LT + +++L DFGFS ++ Q +LS T CGS+ Y APE++RG
Sbjct: 143 SKNIAHRDLKLENIYLTEDMDIRLGDFGFSH---STEKQALLS-TSCGSIYYVAPEVIRG 198
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y + +D+WSLGV+L++M ++P+ + +L++Q + Y ++ +S E
Sbjct: 199 EQYDGQKSDIWSLGVILYIMSTSALPWTEQNQSRLFQQIVSASY----KIPQFVSPEAGN 254
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
+++ L P P R SA +++ S ++
Sbjct: 255 IIQSCLNPIPSKRPSAADLMSSSYV 279
Score = 135 bits (326), Expect = 4e-30
Identities = 68/234 (29%), Positives = 122/234 (52%), Gaps = 8/234 (3%)
Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLL 413
ACK++ T + + +EI L H ++ + I + F+ M Y G+L
Sbjct: 54 ACKIVSRQTLRENETIQHFEQEIRFHQSLKHKNICQLYEIVYEQDFIFLIMEYCANGELF 113
Query: 414 EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFAR 473
E + +R + + Q R + QL A+ Y+H IAHRD+K EN+ LT + +++L DFGF+
Sbjct: 114 ELITKRARLPQYQIRKYFSQLVAAVNYIHSKNIAHRDLKLENIYLTEDMDIRLGDFGFSH 173
Query: 474 MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKH 533
+ L T CGS+ Y APE+++G Y + +D+WSLG+++Y+M A+P+ +++
Sbjct: 174 STEKQAL----LSTSCGSIYYVAPEVIRGEQYDGQKSDIWSLGVILYIMSTSALPWTEQN 229
Query: 534 IKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+L Q ++ ++K +S +I L P R D+++S ++
Sbjct: 230 QSRLFQQIVSASYKIP----QFVSPEAGNIIQSCLNPIPSKRPSAADLMSSSYV 279
>UniRef50_Q94DT7 Cluster: OsPK4-like protein; n=4; Oryza sativa|Rep:
OsPK4-like protein - Oryza sativa subsp. japonica (Rice)
Length = 474
Score = 155 bits (377), Expect = 3e-36
Identities = 83/276 (30%), Positives = 149/276 (53%), Gaps = 9/276 (3%)
Query: 7 TPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVK 66
T S+++ ++ YKL + +G G +AKVY + ++ +A K+ + + V+
Sbjct: 3 TTSQDSQVIMGRYKLGRLLGRGTFAKVYKAYKLATGEA----VAIKVFDKEAVQRSGTVE 58
Query: 67 FLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVW 126
+ RE+DV+ R++H H+I +H + +++ Y M Y G+L + + ++ E AR +
Sbjct: 59 QVKREVDVMRRVHHRHVIRLHEVMATRSRIYFVMEYASGGELFTRLSRSPRFPEPVARRY 118
Query: 127 TRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCG 186
+QL +++ H + HRD+K EN+LL A ++K++DFG S +L T CG
Sbjct: 119 FQQLITAVEFCHSRGVYHRDLKPENLLLDARGDLKVTDFGLSALDGGLRGDGLL-HTTCG 177
Query: 187 SMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRS 246
+ +Y APE+L + Y D+WS GV+LFV+L +PF++T + LY Y
Sbjct: 178 TPAYVAPEVLLKRGYDGAKADIWSCGVILFVLLAGYLPFNETNLVILYRNITESNY---- 233
Query: 247 RVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
R S+E + ++ LL+P+P R + + ++D W
Sbjct: 234 RCPPWFSVEARKLLARLLDPNPKTRITISKIMDRPW 269
Score = 124 bits (299), Expect = 8e-27
Identities = 71/264 (26%), Positives = 134/264 (50%), Gaps = 11/264 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KV D R + + RE++++ ++ H H++ H + R + + M Y G+L
Sbjct: 41 VAIKVFDKEAVQRSGTVEQVKREVDVMRRVHHRHVIRLHEVMATRSRIYFVMEYASGGEL 100
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ + E AR + +QL A+++ H + HRD+K EN+LL A ++K++DFG +
Sbjct: 101 FTRLSRSPRFPEPVARRYFQQLITAVEFCHSRGVYHRDLKPENLLLDARGDLKVTDFGLS 160
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ + + + T CG+ +Y APE+L Y D+WS G++++V+L +PF +
Sbjct: 161 ALDGGLRGDGL-LHTTCGTPAYVAPEVLLKRGYDGAKADIWSCGVILFVLLAGYLPFNET 219
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAM--- 589
++ L++ N+ R S ++L+ +L+PN + R+ I I++ W
Sbjct: 220 NLVILYRNITESNY----RCPPWFSVEARKLLARLLDPNPKTRITISKIMDRPWFQQATC 275
Query: 590 ---DSRLLEWTPQETLAYKKAREE 610
D L+ P LA K+A ++
Sbjct: 276 PLGDMSLVASAPSVLLARKEASQQ 299
>UniRef50_Q84QE0 Cluster: Avr9/Cf-9 rapidly elicited protein 216;
n=2; core eudicotyledons|Rep: Avr9/Cf-9 rapidly elicited
protein 216 - Nicotiana tabacum (Common tobacco)
Length = 413
Score = 155 bits (377), Expect = 3e-36
Identities = 89/265 (33%), Positives = 146/265 (55%), Gaps = 11/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVV-KFLPREIDVLVR 77
Y+L K +G GA AKVY ++E ++ ++A K+I K KD + + + REI +L +
Sbjct: 10 YELGKLLGCGASAKVY----HAREINNGQSVAIKMIN--KNNKDNIPNENIEREISILRQ 63
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
L HP+++ ++ + K+K Y M Y + G+L + I +G SE+ +R + +QL L Y
Sbjct: 64 LRHPYIVKLYEVLATKSKIYFVMEYVKGGELFTKIADHGRFSEDLSRKYFQQLISALNYC 123
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H I HRD+K EN+L+ N ++K+SDFG S + L T CGS +Y APEIL
Sbjct: 124 HSRGIYHRDLKPENILIDENGDLKISDFGLSATTDQIQKFDGLLHTVCGSPAYVAPEILT 183
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
K Y TD+WS G++L+VM+ +PF D + +Y+ K Y+ + +S +
Sbjct: 184 IKGYDGAKTDIWSCGIILYVMIAGYLPFYDQNLMLMYK----KIYKGEFKCPKWMSPDVI 239
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEW 282
++ LL+ +P R + ++ W
Sbjct: 240 RILSRLLDTNPATRITIDEIIKDPW 264
Score = 135 bits (326), Expect = 4e-30
Identities = 71/233 (30%), Positives = 125/233 (53%), Gaps = 4/233 (1%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ REI +L +L HP++V + + + K + M Y++ G+L + G ED +R +
Sbjct: 54 IEREISILRQLRHPYIVKLYEVLATKSKIYFVMEYVKGGELFTKIADHGRFSEDLSRKYF 113
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
+QL A+ Y H I HRD+K EN+L+ N ++K+SDFG + + + T CGS
Sbjct: 114 QQLISALNYCHSRGIYHRDLKPENILIDENGDLKISDFGLSATTDQIQKFDGLLHTVCGS 173
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
+Y APEIL Y TD+WS GI++YVM+ +PF D+++ +++ K +K +
Sbjct: 174 PAYVAPEILTIKGYDGAKTDIWSCGIILYVMIAGYLPFYDQNLMLMYK----KIYKGEFK 229
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLLEWTPQETLAY 604
+S + R++ +L+ N R+ I +I+ W + +++ +E Y
Sbjct: 230 CPKWMSPDVIRILSRLLDTNPATRITIDEIIKDPWFRKGLKFIKFAGEEEDKY 282
>UniRef50_A2EA15 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 347
Score = 155 bits (377), Expect = 3e-36
Identities = 84/266 (31%), Positives = 143/266 (53%), Gaps = 12/266 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y++ +G GA++ V L ++ + ACKI+ ++ + EI + +L
Sbjct: 11 YQMKGDIGHGAFSTVRLCQHLETGKFY----ACKIVSRSRLLMHNLEMRFENEIRISQQL 66
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP ++ ++ + + + YYI + + NG+L + ++ +G ++E +A+V+ QL LQY+H
Sbjct: 67 RHPGVVALYDVLKDEHNYYIIIEFCPNGELFNLVVNSGRLTEPEAKVFICQLLYALQYVH 126
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
L I HRD+K EN+LL N VK+SDFG SRF Q L T CGS YA+PE + G
Sbjct: 127 SLGICHRDLKPENLLLDQNGRVKISDFGLSRFV----GQNGLVSTPCGSPCYASPECVSG 182
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y + +D+WS GV+ + +L +P+ ++L+EQ +Y + LS CK+
Sbjct: 183 QSYDGRKSDIWSCGVITYALLTGQLPWTKRNQQQLFEQIRRGEY----TIPEYLSKSCKS 238
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIA 284
+ L+ + R + L EW+A
Sbjct: 239 FISGLMTVNSDYRMTIEQALHHEWLA 264
Score = 139 bits (337), Expect = 2e-31
Identities = 74/235 (31%), Positives = 124/235 (52%), Gaps = 8/235 (3%)
Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLL 413
ACK++ S ++ EI + +L HP +V + + + + Y+I + + G+L
Sbjct: 38 ACKIVSRSRLLMHNLEMRFENEIRISQQLRHPGVVALYDVLKDEHNYYIIIEFCPNGELF 97
Query: 414 EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFAR 473
V+ G + E +A+++ QL A+QY+H L I HRD+K EN+LL N VK+SDFG +R
Sbjct: 98 NLVVNSGRLTEPEAKVFICQLLYALQYVHSLGICHRDLKPENLLLDQNGRVKISDFGLSR 157
Query: 474 MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKH 533
L T CGS Y +PE + G Y + +D+WS G++ Y +L +P+ ++
Sbjct: 158 FVGQNGL----VSTPCGSPCYASPECVSGQSYDGRKSDIWSCGVITYALLTGQLPWTKRN 213
Query: 534 IKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
+QL + QI + Y +S +CK I ++ N R+ I ++ EW+A
Sbjct: 214 QQQLFE-QIRRGEYTIPEY---LSKSCKSFISGLMTVNSDYRMTIEQALHHEWLA 264
>UniRef50_O18645 Cluster: CG3051-PA, isoform A; n=9; Coelomata|Rep:
CG3051-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 582
Score = 155 bits (376), Expect = 4e-36
Identities = 86/268 (32%), Positives = 139/268 (51%), Gaps = 12/268 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y L +G G + KV + E+ + +A KI+ K VV + REI L
Sbjct: 28 YLLGATLGTGTFGKVKIGEHQIT----RVKVAVKILNRQKIKSLDVVGKIRREIQNLKLF 83
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++ + + ++ M Y G+L YI+K+G + E+QAR + +Q+ G+ Y H
Sbjct: 84 RHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCH 143
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K EN+LL N +VK++DFG S ++ + T CGS +YAAPE++ G
Sbjct: 144 RHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDGE----FLRTSCGSPNYAAPEVISG 199
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS GV+L+ +L ++PFDD + L+ + + + L+ +
Sbjct: 200 KLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIF----PIPEYLNKQVVN 255
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMD 286
+V +L+ DP R + + EW D
Sbjct: 256 LVCQMLQVDPLKRANIEEIKKHEWFQKD 283
Score = 138 bits (334), Expect = 4e-31
Identities = 74/225 (32%), Positives = 121/225 (53%), Gaps = 9/225 (4%)
Query: 366 DFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQED 425
D V K + REI+ L HPH++ + + F+ M Y+ G+L +++++ G +QE
Sbjct: 68 DVVGK-IRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEH 126
Query: 426 QARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRS 485
QAR + +Q+ + Y H I HRD+K EN+LL N +VK++DFG + M +D +
Sbjct: 127 QARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDGEF----L 182
Query: 486 ETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKN 545
T CGS +Y APE++ G Y D+WS G+++Y +L +PF+D+H+ L + +I
Sbjct: 183 RTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFR-KIKSG 241
Query: 546 WKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
Y++ N L+ ML+ + R I +I EW D
Sbjct: 242 IFPIPEYLNKQVVN---LVCQMLQVDPLKRANIEEIKKHEWFQKD 283
>UniRef50_Q8SW31 Cluster: Similarity to SER/THR PROTEIN KINASE KIN1;
n=1; Encephalitozoon cuniculi|Rep: Similarity to SER/THR
PROTEIN KINASE KIN1 - Encephalitozoon cuniculi
Length = 566
Score = 155 bits (376), Expect = 4e-36
Identities = 81/244 (33%), Positives = 134/244 (54%), Gaps = 10/244 (4%)
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
RE+ + LNHPH+ + + T Y++ Y + L I+ +G + E + + + RQ
Sbjct: 111 REVIISSVLNHPHIARLKNFLYSPTHYFLIFEYVKGRQLYDIIISSGPLKEKEGQRYFRQ 170
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
L + Y+H + HRD+K EN+L+ N NVKL DFG S F DN+ +L+ T+CGS+
Sbjct: 171 LLSAIDYIHRNSVVHRDLKIENILIDENDNVKLIDFGLSNF---YDNKTLLN-TFCGSLY 226
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
+AAPE+L+G+ YC D+WSLGVVL+ +L +PFDD ++ L + M ++F
Sbjct: 227 FAAPELLQGQRYCGPEIDVWSLGVVLYAILCGCVPFDDEDVQGLQAKIMDADFKF----C 282
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI--AMDSRLTTLNAVEAAALKRAKEDR 307
+S E +++ ++ P R + V+ SEW+ SR+ + A +K ++
Sbjct: 283 KTISREAMELIRGMIVAQPSSRMGLSQVIGSEWVNKGQKSRINSYAAKRYPIMKLNEKYI 342
Query: 308 RKLS 311
R +S
Sbjct: 343 RPIS 346
Score = 147 bits (355), Expect = 1e-33
Identities = 74/214 (34%), Positives = 118/214 (55%), Gaps = 8/214 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE+ + L+HPH+ + YF+ Y++ L + ++ G ++E + + + RQ
Sbjct: 111 REVIISSVLNHPHIARLKNFLYSPTHYFLIFEYVKGRQLYDIIISSGPLKEKEGQRYFRQ 170
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
L AI Y+H + HRD+K EN+L+ N NVKL DFG + +K L TFCGSL
Sbjct: 171 LLSAIDYIHRNSVVHRDLKIENILIDENDNVKLIDFGLSNFYDNKTL----LNTFCGSLY 226
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
+ APE+LQG Y DVWSLG+V+Y +L +PF+D+ ++ L ++ ++KF
Sbjct: 227 FAAPELLQGQRYCGPEIDVWSLGVVLYAILCGCVPFDDEDVQGLQAKIMDADFKF----C 282
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
TIS LI M+ +R+ + ++ SEW+
Sbjct: 283 KTISREAMELIRGMIVAQPSSRMGLSQVIGSEWV 316
>UniRef50_Q5AG71 Cluster: Potential serine/threonine-protein kinase
Hsl1; n=1; Candida albicans|Rep: Potential
serine/threonine-protein kinase Hsl1 - Candida albicans
(Yeast)
Length = 1462
Score = 155 bits (376), Expect = 4e-36
Identities = 76/217 (35%), Positives = 127/217 (58%), Gaps = 8/217 (3%)
Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127
+ REI ++ ++HP+++ ++ +++ K Y+ + Y E G+L Y++K G + E +A +
Sbjct: 123 IEREIIIMKLISHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIKRGKLQEYEAINYF 182
Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187
+Q+ G+ YLH+ I HRD+K EN+LL N N+K++DFG + V+ L ET CGS
Sbjct: 183 KQIINGINYLHQFNICHRDLKPENLLLDFNKNIKIADFGMAALEVKEK----LLETSCGS 238
Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSR 247
YA+PEI+ GK Y P+D+WS G++LF +L +PFDD +RKL + K+
Sbjct: 239 PHYASPEIVAGKNYHGAPSDIWSCGIILFALLTGHLPFDDENIRKLLLKVQSGKFNMPPE 298
Query: 248 VASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIA 284
LS E K ++ +L+ +P R + +L +A
Sbjct: 299 ----LSFEAKDLITKMLKVNPRERITIDAILTHPLLA 331
Score = 144 bits (349), Expect = 7e-33
Identities = 73/217 (33%), Positives = 132/217 (60%), Gaps = 8/217 (3%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ REI ++ +SHP+++ + +++ + ++ + Y+E G+L +++++RG +QE +A +
Sbjct: 123 IEREIIIMKLISHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIKRGKLQEYEAINYF 182
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
+Q+ I Y+H+ I HRD+K EN+LL N+N+K++DFG A + V +KL ET CGS
Sbjct: 183 KQIINGINYLHQFNICHRDLKPENLLLDFNKNIKIADFGMAALEVKEKL----LETSCGS 238
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y +PEI+ G Y P+D+WS GI+++ +L +PF+D++I++L + K +
Sbjct: 239 PHYASPEIVAGKNYHGAPSDIWSCGIILFALLTGHLPFDDENIRKL----LLKVQSGKFN 294
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
+S K LI ML+ N + R+ I I+ +A
Sbjct: 295 MPPELSFEAKDLITKMLKVNPRERITIDAILTHPLLA 331
>UniRef50_P06782 Cluster: Carbon catabolite-derepressing protein
kinase; n=15; Saccharomycetales|Rep: Carbon
catabolite-derepressing protein kinase - Saccharomyces
cerevisiae (Baker's yeast)
Length = 633
Score = 155 bits (376), Expect = 4e-36
Identities = 87/268 (32%), Positives = 145/268 (54%), Gaps = 13/268 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y++ K +GEG++ KV L +++ +A KII K + + REI L L
Sbjct: 55 YQIVKTLGEGSFGKVKLAYHTTTGQK----VALKIINKKVLAKSDMQGRIEREISYLRLL 110
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++ + + K + + + Y N +L YI++ +SE +AR + +Q+ ++Y H
Sbjct: 111 RHPHIIKLYDVIKSKDEIIMVIEYAGN-ELFDYIVQRDKMSEQEARRFFQQIISAVEYCH 169
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+I HRD+K EN+LL + NVK++DFG S + + +T CGS +YAAPE++ G
Sbjct: 170 RHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGN----FLKTSCGSPNYAAPEVISG 225
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS GV+L+VML + +PFDD + L++ Y + LS
Sbjct: 226 KLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVY----TLPKFLSPGAAG 281
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMD 286
++K +L +P R S ++ +W +D
Sbjct: 282 LIKRMLIVNPLNRISIHEIMQDDWFKVD 309
Score = 144 bits (348), Expect = 9e-33
Identities = 76/238 (31%), Positives = 131/238 (55%), Gaps = 9/238 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I+ + ++ + REI L L HPH++ + + + + + + + Y +L
Sbjct: 81 VALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGN-EL 139
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++QR + E +AR + +Q+ A++Y H +I HRD+K EN+LL + NVK++DFG +
Sbjct: 140 FDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLS 199
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ D +T CGS +Y APE++ G Y DVWS G+++YVML R +PF+D+
Sbjct: 200 NIMTDGNF----LKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDE 255
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
I L + N + +S LI ML N NR+ I++I+ +W +D
Sbjct: 256 SIPVLFKNISNGVYTLPK----FLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVD 309
>UniRef50_A7Q6M5 Cluster: Chromosome chr11 scaffold_56, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr11 scaffold_56, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 467
Score = 155 bits (375), Expect = 5e-36
Identities = 93/271 (34%), Positives = 144/271 (53%), Gaps = 18/271 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L++ +GEG +AKV L + + +A KII+ ++ ++ + REI + L
Sbjct: 10 YQLSRTIGEGTFAKVKL----AVNTENGQYVAIKIIDKHMVMENNLIFQVQREIRTMKLL 65
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDL---LSYILKNGCVSENQARVWTRQLALGLQ 135
+HP+++ +H + KTK YI M Y G L +SY+ K + E AR +QL +
Sbjct: 66 HHPNIVRIHEVIGTKTKIYIVMEYVSGGQLSDKMSYVKK---LDEQDARKHFQQLIDAVD 122
Query: 136 YLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEI 195
Y H ++HRD+K EN+LL + NVK+SDFG S D VLS T CGS Y APE+
Sbjct: 123 YCHGRGVSHRDLKPENLLLDSKGNVKVSDFGLSALRKPGD---VLS-TACGSPCYVAPEL 178
Query: 196 LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLE 255
L + Y D+WS GV+LF +L +PFDD + LY++ +Y +
Sbjct: 179 LANRGYDGAAADIWSCGVILFELLAGYLPFDDRNLMSLYKKITKAEY----TCPEWFTPS 234
Query: 256 CKTVVKHLLEPDPGLRHSATNVLDSEWIAMD 286
++ +LEP+P R S +++ EW +D
Sbjct: 235 QTKLISRILEPNPRRRISIAEIVEDEWFQID 265
Score = 136 bits (328), Expect = 2e-30
Identities = 79/252 (31%), Positives = 133/252 (52%), Gaps = 8/252 (3%)
Query: 339 AEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRY 398
A+ + A + +A K+ID + + + REI + L HP++V H + +
Sbjct: 22 AKVKLAVNTENGQYVAIKIIDKHMVMENNLIFQVQREIRTMKLLHHPNIVRIHEVIGTKT 81
Query: 399 KYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLL 458
K +I M Y+ G L + + + E AR +QL A+ Y H ++HRD+K EN+LL
Sbjct: 82 KIYIVMEYVSGGQLSDKMSYVKKLDEQDARKHFQQLIDAVDYCHGRGVSHRDLKPENLLL 141
Query: 459 TANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIV 518
+ NVK+SDFG + + +K ++ S T CGS Y APE+L Y D+WS G++
Sbjct: 142 DSKGNVKVSDFGLSAL---RKPGDVLS-TACGSPCYVAPELLANRGYDGAAADIWSCGVI 197
Query: 519 VYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKI 578
++ +L +PF+D+++ L++ K K + + + +LI +LEPN + R+ I
Sbjct: 198 LFELLAGYLPFDDRNLMSLYK----KITKAEYTCPEWFTPSQTKLISRILEPNPRRRISI 253
Query: 579 YDIVNSEWIAMD 590
+IV EW +D
Sbjct: 254 AEIVEDEWFQID 265
>UniRef50_A0DEL1 Cluster: Chromosome undetermined scaffold_48, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_48,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 486
Score = 155 bits (375), Expect = 5e-36
Identities = 91/264 (34%), Positives = 145/264 (54%), Gaps = 17/264 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G G + KV L + + T+A KI+ ++ ++ + RE+ +L +
Sbjct: 7 YQLGKTIGSGTFGKVKLAVHIPTQQ----TVAIKIMNKSRMVDIVDIERVQRELHILKIV 62
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP++I ++ +F+ +I M Y + +L SYI+KN + E A +QL G++Y+H
Sbjct: 63 RHPNIIMLYEVFETTKYIFIVMEYCQK-ELFSYIVKNKKIPEVNACALFQQLLSGIEYIH 121
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+L+I HRDIK EN+L+ +K+ DFG S + L +T CGS YAAPE++ G
Sbjct: 122 KLKIVHRDIKPENLLIKGR--IKIVDFGLS------NTYDDLLKTACGSPCYAAPEMISG 173
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS GVVLFVML +PF+D +LY++ + Y +V + LS +
Sbjct: 174 KLYSGLKADIWSSGVVLFVMLCGYLPFEDANTNQLYKKILSANY----KVPNFLSSDAVD 229
Query: 259 VVKHLLEPDPGLRHSATNVLDSEW 282
V+K +L PDP R + + W
Sbjct: 230 VLKLILNPDPEDRPNIDQIRKHPW 253
Score = 118 bits (283), Expect = 7e-25
Identities = 67/213 (31%), Positives = 117/213 (54%), Gaps = 13/213 (6%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE+ +L + HP+++ + +F+ FI M Y ++ +L ++++ + E A +Q
Sbjct: 54 RELHILKIVRHPNIIMLYEVFETTKYIFIVMEYCQK-ELFSYIVKNKKIPEVNACALFQQ 112
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
L I+Y+H+L+I HRDIK EN+L+ +K+ DFG + D +T CGS
Sbjct: 113 LLSGIEYIHKLKIVHRDIKPENLLIKGR--IKIVDFGLSNTYDDLL------KTACGSPC 164
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y APE++ G Y D+WS G+V++VML +PFED + QL++ ++ N+K
Sbjct: 165 YAAPEMISGKLYSGLKADIWSSGVVLFVMLCGYLPFEDANTNQLYKKILSANYKVP---- 220
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+ +S + ++ L+L P+ ++R I I W
Sbjct: 221 NFLSSDAVDVLKLILNPDPEDRPNIDQIRKHPW 253
>UniRef50_Q55H99 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 1430
Score = 155 bits (375), Expect = 5e-36
Identities = 88/275 (32%), Positives = 141/275 (51%), Gaps = 18/275 (6%)
Query: 11 ENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR 70
+N + Y L + +G+G Y V+L +H+ T ++ K PK F L R
Sbjct: 34 DNISVVGNYTLGRVIGQGTYGSVHLA-------THRLTGTRAAVK--KVPKSFT-PHLTR 83
Query: 71 EIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQL 130
E+ RL+HPH++H+H I ++ ++ G+L Y+++ G + E +AR +L
Sbjct: 84 ELHHHRRLHHPHIVHLHEIIATESHIWLVTELCSGGELFDYLVERGRILEGEARRLFGEL 143
Query: 131 ALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSY 190
L + +LH + HRD+K ENVLL +KL D GF+R + L +TYCG+ Y
Sbjct: 144 TLAVGWLHMHGVVHRDLKLENVLLDGELRIKLGDLGFAR----EWQKGRLMDTYCGTTGY 199
Query: 191 AAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVAS 250
A+PE+L + Y TD+WSLG++L+ +L +PFDD R + E +Y
Sbjct: 200 ASPEMLACQKYLGVETDIWSLGIILYTLLCGGLPFDDDDERVMKELIQKGEY----EEPD 255
Query: 251 ILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAM 285
LS E + +++ +L+ DP R S +L W M
Sbjct: 256 WLSQEARDLIRGMLQHDPSKRLSIREILTHPWFKM 290
Score = 137 bits (331), Expect = 1e-30
Identities = 78/237 (32%), Positives = 123/237 (51%), Gaps = 11/237 (4%)
Query: 356 KVIDTSTAPRDFVKKFLP---REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
++ T A + K F P RE+ +L HPH+VH H I ++ G+L
Sbjct: 62 RLTGTRAAVKKVPKSFTPHLTRELHHHRRLHHPHIVHLHEIIATESHIWLVTELCSGGEL 121
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++++RG + E +AR +L LA+ ++H + HRD+K ENVLL +KL D GFA
Sbjct: 122 FDYLVERGRILEGEARRLFGELTLAVGWLHMHGVVHRDLKLENVLLDGELRIKLGDLGFA 181
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
R +L +T+CG+ Y +PE+L YL TD+WSLGI++Y +L +PF+D
Sbjct: 182 REWQKGRL----MDTYCGTTGYASPEMLACQKYLGVETDIWSLGIILYTLLCGGLPFDDD 237
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAM 589
+++ + I K D +S + LI ML+ + RL I +I+ W M
Sbjct: 238 D-ERVMKELIQKG---EYEEPDWLSQEARDLIRGMLQHDPSKRLSIREILTHPWFKM 290
>UniRef50_Q98RL9 Cluster: SNF-related kinase; n=1; Guillardia
theta|Rep: SNF-related kinase - Guillardia theta
(Cryptomonas phi)
Length = 472
Score = 154 bits (374), Expect = 6e-36
Identities = 86/271 (31%), Positives = 148/271 (54%), Gaps = 14/271 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y L K +G G++ KV L E+ + +A KI+ K + + + REI +L
Sbjct: 12 YYLGKTLGVGSFGKVKLGEH----ELCGQKVAVKILNRKKIKNLKMEEKVKREICILKLF 67
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++ + + T ++ Y G+L YI++ G ++E+++R + +Q+ G++Y H
Sbjct: 68 MHPHIIRLYEVIETPTDIFVVTEYITGGELFDYIVERGRLNEDESRKFFQQMISGIEYCH 127
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ HRD+K EN+LL A+ NVK++DFG S + + +T CGS +YAAPE++ G
Sbjct: 128 NHMVVHRDLKPENILLDAHLNVKIADFGLSNIMKDGN----FLKTSCGSPNYAAPEVING 183
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS GV+++ +L S+PFDD + L+++ Y + LS +
Sbjct: 184 KSYLGPEVDVWSCGVIMYALLCGSLPFDDENIPNLFKKIKSGIY----ILPGYLSDLSRD 239
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRL 289
++ +L +P LR + + D W +SRL
Sbjct: 240 MIAKMLITNPLLRITINEIRDHPW--FNSRL 268
Score = 143 bits (347), Expect = 1e-32
Identities = 86/277 (31%), Positives = 152/277 (54%), Gaps = 13/277 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ +++ + REI +L HPH++ + + + F+ Y+ G+L
Sbjct: 38 VAVKILNRKKIKNLKMEEKVKREICILKLFMHPHIIRLYEVIETPTDIFVVTEYITGGEL 97
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++++RG + ED++R + +Q+ I+Y H + HRD+K EN+LL A+ NVK++DFG +
Sbjct: 98 FDYIVERGRLNEDESRKFFQQMISGIEYCHNHMVVHRDLKPENILLDAHLNVKIADFGLS 157
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ D +T CGS +Y APE++ G YL DVWS G+++Y +L ++PF+D+
Sbjct: 158 NIMKDGNF----LKTSCGSPNYAAPEVINGKSYLGPEVDVWSCGVIMYALLCGSLPFDDE 213
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSR 592
+I L + +I Y +SD + +I ML N R+ I +I + W +SR
Sbjct: 214 NIPNLFK-KIKSGIYILPGY---LSDLSRDMIAKMLITNPLLRITINEIRDHPW--FNSR 267
Query: 593 LLEWTPQETLAYKKAREEKNKLHKTVETVELPGSSKT 629
L ++ T +KK + KL+ +EL S+KT
Sbjct: 268 LPKYLSFPT--FKKNFVIQKKLNIDDNILELV-SNKT 301
>UniRef50_Q6BFK9 Cluster: SNF1-related protein kinase, putative;
n=4; Paramecium tetraurelia|Rep: SNF1-related protein
kinase, putative - Paramecium tetraurelia
Length = 562
Score = 154 bits (374), Expect = 6e-36
Identities = 88/278 (31%), Positives = 147/278 (52%), Gaps = 12/278 (4%)
Query: 11 ENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR 70
+ T + Y + K +G G + KV + + + +A KI+E + + V+ + R
Sbjct: 13 QRTRMIGNYAIGKTLGFGTFGKVKMAIHEQSGEK----VAIKILEKDRIVETADVERVQR 68
Query: 71 EIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQL 130
EI +L + HPH+I ++ I + ++ M G+L YI+KN + E +A ++L
Sbjct: 69 EIHILKLVRHPHIIQLYEIIETPKHIFLVMEMVNGGELFDYIVKNTKLEEVEACKLFQEL 128
Query: 131 ALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSY 190
G++YLH++ + HRD+K EN+LL N+K+ DFG S N+ +L +T CGS Y
Sbjct: 129 IAGIEYLHKIRVVHRDLKPENLLLDKGKNLKIVDFGLSN---TYKNEELL-KTACGSPCY 184
Query: 191 AAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVAS 250
AAPE++ GK Y DLWS GV+LF L +PF+D LY++ + Y+ S
Sbjct: 185 AAPEMIAGKKYQGLRVDLWSSGVILFACLCGYLPFEDQNTSALYKKILSGTYQMPSH--- 241
Query: 251 ILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSR 288
LS + ++++ +L DP R + + + W + SR
Sbjct: 242 -LSKDAQSMITGILTVDPEKRFTIETIHNHPWFKIYSR 278
Score = 127 bits (306), Expect = 1e-27
Identities = 69/254 (27%), Positives = 133/254 (52%), Gaps = 8/254 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ + + REI +L + HPH++ + I + F+ M + G+L
Sbjct: 47 VAIKILEKDRIVETADVERVQREIHILKLVRHPHIIQLYEIIETPKHIFLVMEMVNGGEL 106
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++++ ++E +A ++L I+Y+H++ + HRD+K EN+LL +N+K+ DFG +
Sbjct: 107 FDYIVKNTKLEEVEACKLFQELIAGIEYLHKIRVVHRDLKPENLLLDKGKNLKIVDFGLS 166
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ NE +T CGS Y APE++ G Y D+WS G++++ L +PFED+
Sbjct: 167 ----NTYKNEELLKTACGSPCYAAPEMIAGKKYQGLRVDLWSSGVILFACLCGYLPFEDQ 222
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSR 592
+ L++ ++ ++ S +S + + +I +L + + R I I N W + SR
Sbjct: 223 NTSALYKKILSGTYQMPSH----LSKDAQSMITGILTVDPEKRFTIETIHNHPWFKIYSR 278
Query: 593 LLEWTPQETLAYKK 606
E P + Y +
Sbjct: 279 SYEIPPGIVVGYNR 292
>UniRef50_A2F029 Cluster: CAMK family protein kinase; n=3;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 393
Score = 154 bits (374), Expect = 6e-36
Identities = 86/263 (32%), Positives = 142/263 (53%), Gaps = 12/263 (4%)
Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84
VGEGA++ V L K ACK++ + + + EI + +L+HP ++
Sbjct: 22 VGEGAFSIVKLV----LNQKTKQYYACKVVPRDRLLASSLEERFEVEIRIDQQLHHPGIV 77
Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144
+ + + K YY+ M + NGDL +I+ NG ++E+ + +Q+ L+Y+H L IAH
Sbjct: 78 QIVDLLKDKNNYYVVMEFCPNGDLFQFIVDNGRLTEDVGAFYMQQILEALKYVHSLGIAH 137
Query: 145 RDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPK 204
RD+K EN+LL AN N+K+SDFG SR+ V+++ L T CGS YA+PE L G Y
Sbjct: 138 RDLKPENLLLDANNNLKISDFGLSRY-VDTNG---LVNTPCGSPCYASPECLSGSAYEGC 193
Query: 205 PTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLL 264
+D+WS GV+L+ L +P+ ++L+EQ +Y + ++LS EC+ + L+
Sbjct: 194 SSDVWSCGVILYAALTGQLPWTKRNQQQLFEQIKRGEY----TIPNMLSDECRDFISRLM 249
Query: 265 EPDPGLRHSATNVLDSEWIAMDS 287
R + L W+ ++
Sbjct: 250 TVSTSKRMTIDEALKHPWMVKNA 272
Score = 138 bits (335), Expect = 3e-31
Identities = 81/275 (29%), Positives = 139/275 (50%), Gaps = 13/275 (4%)
Query: 318 PKRQGD-ILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREI 376
P+ G+ I +G E AF + +K ACKV+ +++ EI
Sbjct: 10 PQTLGNYIFKGSVGEGAFSIVKLVLNQKTKQ----YYACKVVPRDRLLASSLEERFEVEI 65
Query: 377 EMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLAL 436
+ +L HP +V + + + Y++ M + GDL +F++ G + ED + +Q+
Sbjct: 66 RIDQQLHHPGIVQIVDLLKDKNNYYVVMEFCPNGDLFQFIVDNGRLTEDVGAFYMQQILE 125
Query: 437 AIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTA 496
A++Y+H L IAHRD+K EN+LL AN N+K+SDFG +R L T CGS Y +
Sbjct: 126 ALKYVHSLGIAHRDLKPENLLLDANNNLKISDFGLSRYVDTNGL----VNTPCGSPCYAS 181
Query: 497 PEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTI 556
PE L G+ Y +DVWS G+++Y L +P+ ++ +QL + QI + + +
Sbjct: 182 PECLSGSAYEGCSSDVWSCGVILYAALTGQLPWTKRNQQQLFE-QIKRG---EYTIPNML 237
Query: 557 SDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDS 591
SD C+ I ++ + R+ I + + W+ ++
Sbjct: 238 SDECRDFISRLMTVSTSKRMTIDEALKHPWMVKNA 272
>UniRef50_A2E705 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 497
Score = 154 bits (374), Expect = 6e-36
Identities = 88/255 (34%), Positives = 139/255 (54%), Gaps = 17/255 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETA--KAPKDFVVKFLPREIDVLV 76
Y + + +G GA KV L E+ +K + A KI + + +A D K + RE ++
Sbjct: 11 YIVLQTIGVGATGKVKLGEHKTKH----TLAAIKIFKKSSFEARPDLQQK-IQRETALMR 65
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
L+HPHL+ + I + Y+ + Y +G+L Y++ ++ A + RQ+ GL Y
Sbjct: 66 LLDHPHLLKLKEICESPRHIYVILEYAAHGELFDYLMSRRALTVETAMKFFRQIIYGLDY 125
Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
LH I HRD+K EN+LL N N+K++DFGF+R+ + ++ET CGS YA+PEI+
Sbjct: 126 LHSNNICHRDLKPENILLDDNDNIKIADFGFARWMTAN-----IAETSCGSPHYASPEIV 180
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
+G PY + D+WS GVVL+ +L+ +PFDD R L + +YR I
Sbjct: 181 KGIPYDGRLADIWSCGVVLYALLSGRLPFDDPSFRNLVAKVKAGQYRMPDFPPDI----- 235
Query: 257 KTVVKHLLEPDPGLR 271
K ++ +L+ DP R
Sbjct: 236 KDLISRMLQVDPAKR 250
Score = 134 bits (325), Expect = 5e-30
Identities = 76/243 (31%), Positives = 133/243 (54%), Gaps = 11/243 (4%)
Query: 349 KLSILACKVIDTST-APRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYM 407
K ++ A K+ S+ R +++ + RE ++ L HPHL+ I + ++ + Y
Sbjct: 33 KHTLAAIKIFKKSSFEARPDLQQKIQRETALMRLLDHPHLLKLKEICESPRHIYVILEYA 92
Query: 408 ERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLS 467
G+L ++++ R A+ + A + RQ+ + Y+H I HRD+K EN+LL N N+K++
Sbjct: 93 AHGELFDYLMSRRALTVETAMKFFRQIIYGLDYLHSNNICHRDLKPENILLDDNDNIKIA 152
Query: 468 DFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAM 527
DFGFAR + +ET CGS Y +PEI++G PY + D+WS G+V+Y +L+ +
Sbjct: 153 DFGFARW-----MTANIAETSCGSPHYASPEIVKGIPYDGRLADIWSCGVVLYALLSGRL 207
Query: 528 PFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
PF+D + L A++ K ++R + + K LI ML+ + R+ I I ++
Sbjct: 208 PFDDPSFRNL-VAKV-KAGQYR---MPDFPPDIKDLISRMLQVDPAKRITIEQIKHNRAF 262
Query: 588 AMD 590
+D
Sbjct: 263 RID 265
>UniRef50_A0CGU4 Cluster: Chromosome undetermined scaffold_18, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_18,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 629
Score = 154 bits (374), Expect = 6e-36
Identities = 91/259 (35%), Positives = 145/259 (55%), Gaps = 15/259 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + + +G+G + KVY + + +A KI+E ++ + + REI +L +L
Sbjct: 18 YIIEQSIGKGTFGKVYRGLHKPTQQF----VAIKILEKSRIEQPADFTRIQREIHILRKL 73
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP+++ ++ I + TK Y+ M + G+L +I+KN +SEN+A Q+ ++YLH
Sbjct: 74 RHPNIVQLYEILESDTKIYLIMEFVSGGELFQHIVKNKRLSENEAAALFSQIIEAIEYLH 133
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
L+IAHRD+K EN+LL N N+K+ DFG S + L T CGS YAAPE++ G
Sbjct: 134 SLKIAHRDLKPENLLLENN-NLKVVDFGLSNIYTD------LLSTPCGSPCYAAPEMVSG 186
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y TD+W+ G++L+ ML +PF+D+ RKLYE+ KY R S LS +
Sbjct: 187 IQYSGIKTDIWASGIILYAMLCGYVPFEDSNTRKLYEK---IKYSDFQR-PSHLSPQVID 242
Query: 259 VVKHLLEPDPGLRHSATNV 277
+++ LL +P R S +
Sbjct: 243 LLQGLLNKNPLSRLSIAKI 261
Score = 131 bits (316), Expect = 7e-29
Identities = 71/201 (35%), Positives = 117/201 (58%), Gaps = 12/201 (5%)
Query: 341 YRNASKNDKLSILACKVIDTSTA--PRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRY 398
YR K + +A K+++ S P DF + + REI +L KL HP++V + I +
Sbjct: 33 YRGLHKPTQ-QFVAIKILEKSRIEQPADFTR--IQREIHILRKLRHPNIVQLYEILESDT 89
Query: 399 KYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLL 458
K ++ M ++ G+L + +++ + E++A Q+ AI+Y+H L+IAHRD+K EN+LL
Sbjct: 90 KIYLIMEFVSGGELFQHIVKNKRLSENEAAALFSQIIEAIEYLHSLKIAHRDLKPENLLL 149
Query: 459 TANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIV 518
N N+K+ DFG + + D T CGS Y APE++ G Y TD+W+ GI+
Sbjct: 150 -ENNNLKVVDFGLSNIYTD------LLSTPCGSPCYAAPEMVSGIQYSGIKTDIWASGII 202
Query: 519 VYVMLNRAMPFEDKHIKQLHQ 539
+Y ML +PFED + ++L++
Sbjct: 203 LYAMLCGYVPFEDSNTRKLYE 223
>UniRef50_Q09170 Cluster: Serine/threonine-protein kinase cds1; n=2;
Schizosaccharomyces pombe|Rep: Serine/threonine-protein
kinase cds1 - Schizosaccharomyces pombe (Fission yeast)
Length = 460
Score = 154 bits (374), Expect = 6e-36
Identities = 93/284 (32%), Positives = 149/284 (52%), Gaps = 16/284 (5%)
Query: 9 SEENTLLTKG--YKLTKFVGEGAYAKVYLTEY--SSKEDSHKSTLACKIIETAKAPKDFV 64
S++N + ++ Y++ + +G G +A V L S K + K KI+ T+ +
Sbjct: 155 SQKNMIKSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKR--A 212
Query: 65 VKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQAR 124
+ REID+L L+HP ++ H IF+ + +I M Y E GDL+ +++ NG + E +
Sbjct: 213 TEMFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCK 272
Query: 125 VWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETY 184
+QL L +LH+ + HRDIK EN+L+T +F++K+SDFG ++ ET+
Sbjct: 273 PLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVI---HGTGTFLETF 329
Query: 185 CGSMSYAAPEILRGK------PYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQM 238
CG+M Y APE+L+ K Y K D+WSLG VL+VML S+PF + K E
Sbjct: 330 CGTMGYLAPEVLKSKNVNLDGGYDDK-VDIWSLGCVLYVMLTASIPFASSSQAKCIELIS 388
Query: 239 GKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
Y + + +S E ++ +LE +P R S + L W
Sbjct: 389 KGAYPIEPLLENEISEEGIDLINRMLEINPEKRISESEALQHPW 432
Score = 134 bits (324), Expect = 7e-30
Identities = 82/262 (31%), Positives = 134/262 (51%), Gaps = 11/262 (4%)
Query: 356 KVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEF 415
K++ TS+ R + REI++L L HP +V H IF+ + FI M Y+E GDL++F
Sbjct: 202 KILLTSSEKR--ATEMFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDF 259
Query: 416 VLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMC 475
++ G++ E + +QL + ++H+ + HRDIK EN+L+T + ++K+SDFG A++
Sbjct: 260 LIANGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVI 319
Query: 476 VDKKLNEIRSETFCGSLSYTAPEILQGTPY-----LPKPTDVWSLGIVVYVMLNRAMPFE 530
ETFCG++ Y APE+L+ D+WSLG V+YVML ++PF
Sbjct: 320 HG---TGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFA 376
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
+ + + + IS+ LI MLE N + R+ + + W
Sbjct: 377 SSSQAKCIELISKGAYPIEPLLENEISEEGIDLINRMLEINPEKRISESEALQHPWFYTV 436
Query: 591 SRLLEWTPQETLAYKKAREEKN 612
S TP + + +A E+ N
Sbjct: 437 STHEHRTPPSSSEH-EATEQLN 457
>UniRef50_A2EUJ6 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 419
Score = 154 bits (373), Expect = 8e-36
Identities = 91/269 (33%), Positives = 154/269 (57%), Gaps = 17/269 (6%)
Query: 19 YKLTKFVGEGAYAKVYL-TEYSSKEDSHKSTLACKIIETAK-APKDFVVKFLPREIDVLV 76
Y + + +G GA++ V+ T +K D +A K+I + F+ +F+ RE+++L
Sbjct: 16 YTIGEKIGSGAFSSVFKGTHMLTKID-----VAIKVISKKSFTDQKFITRFM-REVNLLK 69
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
++NHP + ++ +++ + +Y+ M Y+ NGDLLS+I KNG + E AR + QL L+Y
Sbjct: 70 QMNHPMINELYDLYEDEKYHYLIMEYSPNGDLLSFINKNGKLIEPIARRYFTQLFSVLEY 129
Query: 137 LH-ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEI 195
LH E ++AHRD+K EN+LL FN+++ DFG S C +N + ET CGS +Y PE+
Sbjct: 130 LHKERKVAHRDLKAENILLDRYFNLRIIDFGLSN-CFTDENN--VFETKCGSPAYIPPEM 186
Query: 196 LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLE 255
+ G Y P D+WS GV+L+ M S+PFDD ++K + + + ++ L+
Sbjct: 187 IIGYGYTP-AADMWSTGVLLYAMSIGSLPFDDENVKKTLQLIVYANPTYPPSISPALA-- 243
Query: 256 CKTVVKHLLEPDPGLRHSATNVLDSEWIA 284
+++ LL DP LR + + + W +
Sbjct: 244 --DLLQKLLTKDPLLRITLDKIKEHPWFS 270
Score = 126 bits (305), Expect = 1e-27
Identities = 68/214 (31%), Positives = 124/214 (57%), Gaps = 7/214 (3%)
Query: 353 LACKVIDT-STAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A KVI S + F+ +F+ RE+ +L +++HP + + +++ +++ M Y GD
Sbjct: 42 VAIKVISKKSFTDQKFITRFM-REVNLLKQMNHPMINELYDLYEDEKYHYLIMEYSPNGD 100
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMH-ELEIAHRDIKCENVLLTANQNVKLSDFG 470
LL F+ + G + E AR + QL ++Y+H E ++AHRD+K EN+LL N+++ DFG
Sbjct: 101 LLSFINKNGKLIEPIARRYFTQLFSVLEYLHKERKVAHRDLKAENILLDRYFNLRIIDFG 160
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+ D+ N + ET CGS +Y PE++ G Y P D+WS G+++Y M ++PF+
Sbjct: 161 LSNCFTDE--NNV-FETKCGSPAYIPPEMIIGYGYTP-AADMWSTGVLLYAMSIGSLPFD 216
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLI 564
D+++K+ Q + N + ++D ++L+
Sbjct: 217 DENVKKTLQLIVYANPTYPPSISPALADLLQKLL 250
>UniRef50_Q7R2W2 Cluster: GLP_291_14488_15897; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_14488_15897 - Giardia lamblia
ATCC 50803
Length = 469
Score = 153 bits (372), Expect = 1e-35
Identities = 87/276 (31%), Positives = 150/276 (54%), Gaps = 10/276 (3%)
Query: 9 SEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68
S+E + Y++++ +G GA+AKV L ++++D+ K A KII+ + + L
Sbjct: 2 SDEQPVQLGQYEVSELLGSGAFAKVRL---ATRKDTGKK-YAVKIIKKVGLSQRAADR-L 56
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTR 128
EI V ++HP++I +H + +K+++ M Y NG+LL ++ +S++QA +
Sbjct: 57 NLEIAVTKGISHPNVIKMHEVIGTSSKFWLVMDYHANGELLKHMKTK--LSDDQAFDYFI 114
Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
Q+A L+Y H I HRD+K ENVL+ + ++ ++DFG D T+CGS
Sbjct: 115 QIACALRYCHRFGICHRDLKFENVLVANDGHLVITDFGLGAISYNPDKTFYSQATFCGST 174
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
Y APE+ G Y + +D+WSLG++L+ ML +PF L E + ++Y +
Sbjct: 175 HYIAPEVSSGSRYDGRKSDIWSLGIMLYAMLIGKLPFPSDNYEVLVESMLNRRY---DPI 231
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIA 284
S ++ + K +++ LLEPDP R + + WIA
Sbjct: 232 PSFVNDQAKNLLEALLEPDPRTRPDWREIFNYPWIA 267
Score = 134 bits (324), Expect = 7e-30
Identities = 77/257 (29%), Positives = 136/257 (52%), Gaps = 6/257 (2%)
Query: 339 AEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRY 398
A+ R A++ D A K+I + + L EI + +SHP+++ H +
Sbjct: 24 AKVRLATRKDTGKKYAVKIIKKVGLSQRAADR-LNLEIAVTKGISHPNVIKMHEVIGTSS 82
Query: 399 KYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLL 458
K+++ M Y G+LL+ + + + +DQA + Q+A A++Y H I HRD+K ENVL+
Sbjct: 83 KFWLVMDYHANGELLKHMKTK--LSDDQAFDYFIQIACALRYCHRFGICHRDLKFENVLV 140
Query: 459 TANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIV 518
+ ++ ++DFG + + TFCGS Y APE+ G+ Y + +D+WSLGI+
Sbjct: 141 ANDGHLVITDFGLGAISYNPDKTFYSQATFCGSTHYIAPEVSSGSRYDGRKSDIWSLGIM 200
Query: 519 VYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKI 578
+Y ML +PF + + L ++ +N+ + + ++D K L+ +LEP+ + R
Sbjct: 201 LYAMLIGKLPFPSDNYEVLVESMLNRRYDPIPSF---VNDQAKNLLEALLEPDPRTRPDW 257
Query: 579 YDIVNSEWIAMDSRLLE 595
+I N WIA L++
Sbjct: 258 REIFNYPWIASRVALVD 274
>UniRef50_A2GAV1 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 353
Score = 153 bits (372), Expect = 1e-35
Identities = 88/273 (32%), Positives = 141/273 (51%), Gaps = 12/273 (4%)
Query: 17 KGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLV 76
+ Y+ + +G G+++ V L + K ACKI+ + + +E+ ++
Sbjct: 21 ENYEFVRKIGYGSFSSVVLVRHLKT----KEYFACKIVSRKMLEEQQIFSRFEQEVRLMQ 76
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
NHP++IH + YI M Y NG+L SYIL + E + RQ+ LQY
Sbjct: 77 SFNHPYVIHTFDVVFDPQYIYIVMEYCPNGELFSYILSLVRLPEMEVNRILRQILQALQY 136
Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
+H ++AHRDIK EN+LL ++ +++LSDFG C E + +L +T CGS YA PEI+
Sbjct: 137 IHSKKVAHRDIKPENILLDSHMDIRLSDFG---LCKEMSHGSLL-KTPCGSPFYAPPEII 192
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
Y +D+WSLGVV+F M ++P+ T +L++Q V LS
Sbjct: 193 NNDKYDGVKSDIWSLGVVVFTMSTGALPWSHTNHAQLFKQITTTDV----TVPQGLSPPL 248
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRL 289
+ ++ +L+ DP R + T +L W+A DS +
Sbjct: 249 RQIITLMLQRDPNARPTPTELLAMPWLADDSSI 281
Score = 124 bits (299), Expect = 8e-27
Identities = 72/241 (29%), Positives = 126/241 (52%), Gaps = 10/241 (4%)
Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSI-FQRRYKYFIFMRYMERGDL 412
ACK++ + +E+ ++ +HP+++HT + F +Y Y + M Y G+L
Sbjct: 50 ACKIVSRKMLEEQQIFSRFEQEVRLMQSFNHPYVIHTFDVVFDPQYIYIV-MEYCPNGEL 108
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++L + E + RQ+ A+QY+H ++AHRDIK EN+LL ++ +++LSDFG
Sbjct: 109 FSYILSLVRLPEMEVNRILRQILQALQYIHSKKVAHRDIKPENILLDSHMDIRLSDFG-- 166
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+C + + +T CGS Y PEI+ Y +D+WSLG+VV+ M A+P+
Sbjct: 167 -LCKEMSHGSL-LKTPCGSPFYAPPEIINNDKYDGVKSDIWSLGVVVFTMSTGALPWSHT 224
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSR 592
+ QL + QI +S +++I LML+ + R +++ W+A DS
Sbjct: 225 NHAQLFK-QITTT---DVTVPQGLSPPLRQIITLMLQRDPNARPTPTELLAMPWLADDSS 280
Query: 593 L 593
+
Sbjct: 281 I 281
>UniRef50_A0EBP2 Cluster: Chromosome undetermined scaffold_88, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_88,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 648
Score = 153 bits (372), Expect = 1e-35
Identities = 84/274 (30%), Positives = 146/274 (53%), Gaps = 12/274 (4%)
Query: 17 KGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLV 76
+ Y + K +G+G + KV + + + +A KI+E K + + REI +L
Sbjct: 16 QNYVVDKTLGQGTFGKVKMGIHKCTNEK----VAIKILEKEKIENEADYVRIQREIHILR 71
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
++ HP++I ++ I + + K Y+ Y G+L +I+ + E +A QL ++Y
Sbjct: 72 KIRHPNIIQLYEIIESEIKLYLITEYAPGGELFEHIVSKSRLEEREAGRIFFQLLNAIEY 131
Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
+H+L I HRD+K EN+LL +N VK+ DFG S + NQ + T CGS YAAPE++
Sbjct: 132 IHQLGIVHRDLKPENILLDSNKQVKVVDFGLSN--LYQPNQKL--HTPCGSPCYAAPEMV 187
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
G PY TD+WS G++L+ M+ +PF+D ++LYE+ Y+ V S +
Sbjct: 188 SGLPYEGLKTDIWSCGIILYAMICGCVPFEDQNTKQLYEKIKHSDYKLPKSV----SPQA 243
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLT 290
+++ +L+ DP R + + ++I ++T
Sbjct: 244 ADLLRKILQKDPSKRITIPEIRQHDFILFAGKMT 277
Score = 140 bits (339), Expect = 1e-31
Identities = 73/228 (32%), Positives = 130/228 (57%), Gaps = 10/228 (4%)
Query: 366 DFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQED 425
D+V+ + REI +L K+ HP+++ + I + K ++ Y G+L E ++ + ++E
Sbjct: 59 DYVR--IQREIHILRKIRHPNIIQLYEIIESEIKLYLITEYAPGGELFEHIVSKSRLEER 116
Query: 426 QARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRS 485
+A QL AI+Y+H+L I HRD+K EN+LL +N+ VK+ DFG + + + +
Sbjct: 117 EAGRIFFQLLNAIEYIHQLGIVHRDLKPENILLDSNKQVKVVDFGLSNLYQPNQ----KL 172
Query: 486 ETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKN 545
T CGS Y APE++ G PY TD+WS GI++Y M+ +PFED++ KQL++ + +
Sbjct: 173 HTPCGSPCYAAPEMVSGLPYEGLKTDIWSCGIILYAMICGCVPFEDQNTKQLYEKIKHSD 232
Query: 546 WKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRL 593
+K ++S L+ +L+ + R+ I +I ++I ++
Sbjct: 233 YKLPK----SVSPQAADLLRKILQKDPSKRITIPEIRQHDFILFAGKM 276
>UniRef50_Q14680 Cluster: Maternal embryonic leucine zipper kinase;
n=37; Tetrapoda|Rep: Maternal embryonic leucine zipper
kinase - Homo sapiens (Human)
Length = 651
Score = 153 bits (372), Expect = 1e-35
Identities = 89/273 (32%), Positives = 145/273 (53%), Gaps = 14/273 (5%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
L K Y+L + +G G +AKV L + + +A KI++ D + + EI+
Sbjct: 7 LLKYYELHETIGTGGFAKVKLACHILTGEM----VAIKIMDKNTLGSD--LPRIKTEIEA 60
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
L L H H+ ++ + + K ++ + Y G+L YI+ +SE + RV RQ+ +
Sbjct: 61 LKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAV 120
Query: 135 QYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVE-SDNQPVLSETYCGSMSYAAP 193
Y+H AHRD+K EN+L +KL DFG C + N+ +T CGS++YAAP
Sbjct: 121 AYVHSQGYAHRDLKPENLLFDEYHKLKLIDFG---LCAKPKGNKDYHLQTCCGSLAYAAP 177
Query: 194 EILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILS 253
E+++GK Y D+WS+G++L+V++ +PFDD + LY++ M KY V LS
Sbjct: 178 ELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKY----DVPKWLS 233
Query: 254 LECKTVVKHLLEPDPGLRHSATNVLDSEWIAMD 286
+++ +L+ DP R S N+L+ WI D
Sbjct: 234 PSSILLLQQMLQVDPKKRISMKNLLNHPWIMQD 266
Score = 145 bits (351), Expect = 4e-33
Identities = 77/247 (31%), Positives = 137/247 (55%), Gaps = 11/247 (4%)
Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
++A K++D +T D + + EIE L L H H+ + + + K F+ + Y G+
Sbjct: 36 MVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGE 93
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
L ++++ + + E++ R+ RQ+ A+ Y+H AHRD+K EN+L +KL DFG
Sbjct: 94 LFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFG- 152
Query: 472 ARMCVDKKLN-EIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+C K N + +T CGSL+Y APE++QG YL DVWS+GI++YV++ +PF+
Sbjct: 153 --LCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFD 210
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
D ++ L++ K + + +S + L+ ML+ + + R+ + +++N WI D
Sbjct: 211 DDNVMALYK----KIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQD 266
Query: 591 SRL-LEW 596
+EW
Sbjct: 267 YNYPVEW 273
>UniRef50_Q8IWQ3 Cluster: BR serine/threonine-protein kinase 2;
n=27; Eumetazoa|Rep: BR serine/threonine-protein kinase
2 - Homo sapiens (Human)
Length = 736
Score = 153 bits (371), Expect = 1e-35
Identities = 82/264 (31%), Positives = 143/264 (54%), Gaps = 13/264 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G+G V L + +A KI+ K + ++K + REI +L +
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQK----VAIKIVNREKLSESVLMK-VEREIAILKLI 73
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH++ +H +++ K Y+ + + G+L Y++K G ++ +AR + RQ+ L + H
Sbjct: 74 EHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCH 133
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K EN+LL N++++DFG + V L ET CGS YA PE++RG
Sbjct: 134 SHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDS----LLETSCGSPHYACPEVIRG 189
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y + D+WS GV+LF +L ++PFDD +R+L E K R + + +C++
Sbjct: 190 EKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLE----KVKRGVFHMPHFIPPDCQS 245
Query: 259 VVKHLLEPDPGLRHSATNVLDSEW 282
+++ ++E D R + ++ W
Sbjct: 246 LLRGMIEVDAARRLTLEHIQKHIW 269
Score = 136 bits (330), Expect = 1e-30
Identities = 69/234 (29%), Positives = 130/234 (55%), Gaps = 9/234 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ + K + REI +L + HPH++ H +++ + ++ + ++ G+L
Sbjct: 45 VAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGEL 103
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++++G + +AR + RQ+ A+ + H I HRD+K EN+LL N++++DFG A
Sbjct: 104 FDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA 163
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ V L ET CGS Y PE+++G Y + DVWS G++++ +L A+PF+D
Sbjct: 164 SLQVGDSL----LETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDD 219
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+++QL + K F + I +C+ L+ M+E + RL + I W
Sbjct: 220 NLRQLLEKV--KRGVFHMPHF--IPPDCQSLLRGMIEVDAARRLTLEHIQKHIW 269
>UniRef50_UPI0000519D29 Cluster: PREDICTED: similar to maternal
embryonic leucine zipper kinase; n=2; Endopterygota|Rep:
PREDICTED: similar to maternal embryonic leucine zipper
kinase - Apis mellifera
Length = 606
Score = 153 bits (370), Expect = 2e-35
Identities = 90/269 (33%), Positives = 143/269 (53%), Gaps = 20/269 (7%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR---EIDVL 75
Y L K +G G +AKV L + + + +A KI++ D LPR E+ L
Sbjct: 11 YDLEKTIGSGGFAKVKLATHIATGEK----VAIKIMDKTSLGDD-----LPRVKLEVQAL 61
Query: 76 VRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQ 135
L H H+ ++ + + ++ Y++ + Y G+L +I++ +SE ++R + RQ+ +
Sbjct: 62 KTLLHQHICRLYQVIETESHYFMVIEYCSGGELFDHIVEKNKLSETESRKFFRQIVSAVA 121
Query: 136 YLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQ-PVLSETYCGSMSYAAPE 194
YLH L AHRD+K ENVLL N+KL DFG C + N +T CGS +YAAPE
Sbjct: 122 YLHSLGYAHRDLKPENVLLDKEENLKLIDFG---LCAKPKNGIDSHLQTSCGSPTYAAPE 178
Query: 195 ILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSL 254
++ GK Y D+WS+GV+L+ +L +PFDD + LY + + KY S LS
Sbjct: 179 LILGKKYLGSEVDIWSMGVLLYALLCGFLPFDDNNIENLYRKILSGKY----DEPSWLSS 234
Query: 255 ECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
K +++ +L+ DP R + + + WI
Sbjct: 235 SSKKLIQAMLQIDPKKRITIQELCNHPWI 263
Score = 147 bits (357), Expect = 7e-34
Identities = 78/237 (32%), Positives = 137/237 (57%), Gaps = 12/237 (5%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++D ++ D + L E++ L L H H+ + + + YF+ + Y G+L
Sbjct: 37 VAIKIMDKTSLGDDLPRVKL--EVQALKTLLHQHICRLYQVIETESHYFMVIEYCSGGEL 94
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ ++++ + E ++R + RQ+ A+ Y+H L AHRD+K ENVLL +N+KL DFG
Sbjct: 95 FDHIVEKNKLSETESRKFFRQIVSAVAYLHSLGYAHRDLKPENVLLDKEENLKLIDFG-- 152
Query: 473 RMCVDKKLNEIRS--ETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+C K N I S +T CGS +Y APE++ G YL D+WS+G+++Y +L +PF+
Sbjct: 153 -LCAKPK-NGIDSHLQTSCGSPTYAAPELILGKKYLGSEVDIWSMGVLLYALLCGFLPFD 210
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
D +I+ L++ ++ + S +S + K+LI ML+ + + R+ I ++ N WI
Sbjct: 211 DNNIENLYRKILSGKYDEPS----WLSSSSKKLIQAMLQIDPKKRITIQELCNHPWI 263
>UniRef50_Q7QBH3 Cluster: ENSANGP00000014786; n=3; Culicidae|Rep:
ENSANGP00000014786 - Anopheles gambiae str. PEST
Length = 1136
Score = 153 bits (370), Expect = 2e-35
Identities = 86/285 (30%), Positives = 153/285 (53%), Gaps = 13/285 (4%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
L + + + K +G+G Y KV L +KE + +A K I+ +K + + + RE+ +
Sbjct: 23 LRQRFDIIKKLGQGTYGKVQLG--INKETGQE--VAIKTIKKSKIETEADLIRIRREVQI 78
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
+ + HP++IH++ +F+ + K + M + G+L Y+ + ++E +AR RQ++ +
Sbjct: 79 MSSVQHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERKVLAEEEARRIFRQVSTAI 138
Query: 135 QYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPE 194
Y H+ +I HRD+K EN+LL + N K++DFG S D Q +L+ T+CGS YA+PE
Sbjct: 139 YYCHKHKICHRDLKLENILLDEHGNAKIADFGLSNV---FDEQRLLA-TFCGSPLYASPE 194
Query: 195 ILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSL 254
I++G PY D WSLGV+L+ ++ +MPFD ++L +Q Y F + S
Sbjct: 195 IVKGTPYQGPEVDCWSLGVLLYTLVYGAMPFDGANFKRLVKQISQGDY-FEPKKPS---- 249
Query: 255 ECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAA 299
+++ +L P R + + + W+ + L+ E A
Sbjct: 250 RASPLIREMLTVCPSHRANIEQICNHWWVNEGYEESCLDLAEELA 294
Score = 145 bits (351), Expect = 4e-33
Identities = 81/274 (29%), Positives = 153/274 (55%), Gaps = 14/274 (5%)
Query: 314 HKHPPKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLP 373
H+ +++ DI++ + + +V L + + + + I+T D ++ +
Sbjct: 19 HRKKLRQRFDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKSKIETEA---DLIR--IR 73
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE++++ + HP+++H + +F+ R K + M + G+L +++ +R + E++AR RQ
Sbjct: 74 REVQIMSSVQHPNIIHIYEVFENREKMVLVMEFAAGGELYDYLSERKVLAEEEARRIFRQ 133
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
++ AI Y H+ +I HRD+K EN+LL + N K++DFG + + +++L TFCGS
Sbjct: 134 VSTAIYYCHKHKICHRDLKLENILLDEHGNAKIADFGLSNVFDEQRL----LATFCGSPL 189
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y +PEI++GTPY D WSLG+++Y ++ AMPF+ + K+L + QI++ F +
Sbjct: 190 YASPEIVKGTPYQGPEVDCWSLGVLLYTLVYGAMPFDGANFKRLVK-QISQGDYFEPKKP 248
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
S + + L + P+H R I I N W+
Sbjct: 249 SRASPLIREM--LTVCPSH--RANIEQICNHWWV 278
>UniRef50_A4I4Q9 Cluster: Serine/threonine protein kinase, putative;
n=3; Leishmania|Rep: Serine/threonine protein kinase,
putative - Leishmania infantum
Length = 815
Score = 153 bits (370), Expect = 2e-35
Identities = 94/307 (30%), Positives = 156/307 (50%), Gaps = 22/307 (7%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKST---LACKIIETAKAPKDFVVKFLPREIDVL 75
Y + + +G G++ KV K+ H T +A KI+ K + K + REI++L
Sbjct: 36 YVIRETIGRGSFGKV-------KKGRHVHTGEYVAIKILNRQKLKSANMDKKIHREIEIL 88
Query: 76 VRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQ 135
+HP++ ++ + T Y+ M Y E G+L YI++ G V E++AR +Q+ ++
Sbjct: 89 QLFSHPNICRLYEVISTPTDMYLIMEYVEGGELYDYIVQKGRVRESEARYIFQQIVCAIE 148
Query: 136 YLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEI 195
Y H + HRD+K EN+LL VKL DFG S + + T CGS +YAAPE+
Sbjct: 149 YCHHFRVVHRDLKPENILLGTGLQVKLIDFGLSNITKDGE----FLATSCGSPNYAAPEV 204
Query: 196 LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLE 255
+ GK Y D+WS GV+L+ +L +PFD+ + L+ + KY + S +
Sbjct: 205 ISGKLYFGPEVDVWSCGVILYALLCGCLPFDEDSIPLLFSKIKKGKY----AIPSNMQTG 260
Query: 256 CKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKEDRRKLSDVHK 315
+ +++ +L DP +R + + D+ W + RL + + ++ KED R LS +
Sbjct: 261 PRELIQQILVVDPLVRLTVPQIRDNAW--FNQRL-PMRLSYSESIFSVKED-RILSVLVS 316
Query: 316 HPPKRQG 322
KR G
Sbjct: 317 ETAKRLG 323
Score = 132 bits (320), Expect = 2e-29
Identities = 63/185 (34%), Positives = 104/185 (56%), Gaps = 4/185 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ + K + REIE+L SHP++ + + ++ M Y+E G+L
Sbjct: 62 VAIKILNRQKLKSANMDKKIHREIEILQLFSHPNICRLYEVISTPTDMYLIMEYVEGGEL 121
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++Q+G V+E +AR +Q+ AI+Y H + HRD+K EN+LL VKL DFG +
Sbjct: 122 YDYIVQKGRVRESEARYIFQQIVCAIEYCHHFRVVHRDLKPENILLGTGLQVKLIDFGLS 181
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ D + T CGS +Y APE++ G Y DVWS G+++Y +L +PF++
Sbjct: 182 NITKDGEF----LATSCGSPNYAAPEVISGKLYFGPEVDVWSCGVILYALLCGCLPFDED 237
Query: 533 HIKQL 537
I L
Sbjct: 238 SIPLL 242
>UniRef50_Q17M45 Cluster: Br serine/threonine-protein kinase; n=2;
Culicidae|Rep: Br serine/threonine-protein kinase -
Aedes aegypti (Yellowfever mosquito)
Length = 774
Score = 152 bits (369), Expect = 2e-35
Identities = 84/280 (30%), Positives = 151/280 (53%), Gaps = 17/280 (6%)
Query: 6 TTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVV 65
+TPS E Y+L + +G+G V L + +A KII K + ++
Sbjct: 10 STPSNEAHQYVGPYRLERTLGKGQTGLVKLGVHCVTAKK----VAIKIINREKLSESVLM 65
Query: 66 KFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARV 125
K + REI ++ ++HPH++ + +++ + Y+ + + G+L Y++K G ++ +AR
Sbjct: 66 K-VEREIAIMKLIDHPHVLGLTDVYENRKYLYLVLEHVSGGELFDYLVKKGRLTPKEARK 124
Query: 126 WTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPV--LSET 183
+ RQ+ L + H I HRD+K EN+LL N+K++DFG + QP + ET
Sbjct: 125 FFRQIISALDFCHSHSICHRDLKPENLLLDDKNNIKIADFGMASL------QPAGSMLET 178
Query: 184 YCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYR 243
CGS YA PE++RG+ Y + D+WS GV+L+ +L ++PFDD +R+L E K R
Sbjct: 179 SCGSPHYACPEVIRGEKYDGRRADVWSCGVILYALLVGALPFDDDNLRQLLE----KVKR 234
Query: 244 FRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ + +C++++K ++E +P R + + + W+
Sbjct: 235 GVFHIPHFVPPDCQSLLKGMIEVNPEKRLTLSEINKHPWV 274
Score = 136 bits (329), Expect = 2e-30
Identities = 69/235 (29%), Positives = 131/235 (55%), Gaps = 9/235 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I+ + K + REI ++ + HPH++ +++ R ++ + ++ G+L
Sbjct: 49 VAIKIINREKLSESVLMK-VEREIAIMKLIDHPHVLGLTDVYENRKYLYLVLEHVSGGEL 107
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++++G + +AR + RQ+ A+ + H I HRD+K EN+LL N+K++DFG A
Sbjct: 108 FDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDDKNNIKIADFGMA 167
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ + ET CGS Y PE+++G Y + DVWS G+++Y +L A+PF+D
Sbjct: 168 SLQPAGSM----LETSCGSPHYACPEVIRGEKYDGRRADVWSCGVILYALLVGALPFDDD 223
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+++QL + K F + + +C+ L+ M+E N + RL + +I W+
Sbjct: 224 NLRQLLEKV--KRGVFHIPHF--VPPDCQSLLKGMIEVNPEKRLTLSEINKHPWV 274
>UniRef50_UPI0000DA406D Cluster: PREDICTED: similar to
serine/threonine kinase; n=6; Murinae|Rep: PREDICTED:
similar to serine/threonine kinase - Rattus norvegicus
Length = 739
Score = 152 bits (368), Expect = 3e-35
Identities = 98/304 (32%), Positives = 165/304 (54%), Gaps = 22/304 (7%)
Query: 3 DLKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKST-LACKIIETAKAPK 61
+L+ +PSEE TL T Y + + +G+G++A+V L + H +A K++E +
Sbjct: 4 ELEASPSEEVTL-TDHYMILRTLGKGSFAEVKLACHL-----HTGVWVAVKVLERGEK-N 56
Query: 62 DFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSEN 121
D V+ EID++ L+HP++I + + + + + Y+ M + GDL+S+I K GC+ E
Sbjct: 57 DSVIM---TEIDIIKSLDHPNIIKLFHVIESRERTYMVMEHAAGGDLVSHIEKVGCLQEE 113
Query: 122 QA-RVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVL 180
+ R++T Q+ + Y HE IAHRDIK +N+LL N +VKL DFG + V S +
Sbjct: 114 ETHRIFT-QMVRAVSYCHENSIAHRDIKPDNILLDGNGSVKLCDFGLA-IKVTSGQR--- 168
Query: 181 SETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGK 240
+ +CG++ Y APEI Y + D+WS+GVVL+ M+ PF+ ++ E+ +
Sbjct: 169 FKGFCGTLEYCAPEIFTDVEYDAQANDIWSMGVVLYTMVTGRFPFEAKTYSQMKEKMLHP 228
Query: 241 KYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTL-NAVEAAA 299
KY + +LS +++ L DP R +V+ +W+ L+ L ++ EA
Sbjct: 229 KY----SIPPMLSPNIASLIVQLFTVDPDQRPKICDVMQHQWLRGGEDLSKLASSSEACP 284
Query: 300 LKRA 303
K A
Sbjct: 285 SKPA 288
Score = 133 bits (322), Expect = 1e-29
Identities = 72/214 (33%), Positives = 117/214 (54%), Gaps = 10/214 (4%)
Query: 375 EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQA-RIWTRQ 433
EI+++ L HP+++ + + R + ++ M + GDL+ + + G +QE++ RI+T Q
Sbjct: 63 EIDIIKSLDHPNIIKLFHVIESRERTYMVMEHAAGGDLVSHIEKVGCLQEEETHRIFT-Q 121
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+ A+ Y HE IAHRDIK +N+LL N +VKL DFG A K + R + FCG+L
Sbjct: 122 MVRAVSYCHENSIAHRDIKPDNILLDGNGSVKLCDFGLA----IKVTSGQRFKGFCGTLE 177
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y APEI Y + D+WS+G+V+Y M+ PFE K Q+ + ++ +
Sbjct: 178 YCAPEIFTDVEYDAQANDIWSMGVVLYTMVTGRFPFEAKTYSQMKEKMLHPKYSIP---- 233
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+S N LI + + R KI D++ +W+
Sbjct: 234 PMLSPNIASLIVQLFTVDPDQRPKICDVMQHQWL 267
>UniRef50_A2GCT3 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 484
Score = 152 bits (368), Expect = 3e-35
Identities = 78/225 (34%), Positives = 129/225 (57%), Gaps = 10/225 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAK-APKDFVVKFLPREIDVLVR 77
Y + + +G G KV L ++ + + A KII+ + A K + + REI ++
Sbjct: 11 YNIIRTLGSGTTCKVKLAQHQLTGEYY----AIKIIKKSHFAQKPNLEMKIYREISLMRM 66
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
++HPH+I +H + + YI + Y +NG+L Y++++ C+ E+ A RQ+ L+YL
Sbjct: 67 VDHPHIIKLHDVLESPRHIYIILEYAQNGELFDYLVRSKCLKEDVAMDMFRQIIYALEYL 126
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H I HRD+K EN+LL N +K++DFGF+R+ + ++ T CGS YAAPE++R
Sbjct: 127 HLHNICHRDLKPENILLDKNNRIKIADFGFARWM-----RHCVANTSCGSPHYAAPEVIR 181
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKY 242
G Y + D+WS GV+LF +L +PFDD + L ++ K+
Sbjct: 182 GYEYDGRAADIWSAGVILFALLAGYLPFDDHSIHILLQKVKRGKF 226
Score = 132 bits (318), Expect = 4e-29
Identities = 65/212 (30%), Positives = 116/212 (54%), Gaps = 6/212 (2%)
Query: 354 ACKVIDTST-APRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
A K+I S A + ++ + REI ++ + HPH++ H + + +I + Y + G+L
Sbjct: 38 AIKIIKKSHFAQKPNLEMKIYREISLMRMVDHPHIIKLHDVLESPRHIYIILEYAQNGEL 97
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++++ ++ED A RQ+ A++Y+H I HRD+K EN+LL N +K++DFGFA
Sbjct: 98 FDYLVRSKCLKEDVAMDMFRQIIYALEYLHLHNICHRDLKPENILLDKNNRIKIADFGFA 157
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
R + + T CGS Y APE+++G Y + D+WS G++++ +L +PF+D
Sbjct: 158 RW-----MRHCVANTSCGSPHYAAPEVIRGYEYDGRAADIWSAGVILFALLAGYLPFDDH 212
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLI 564
I L Q + + + D +R+I
Sbjct: 213 SIHILLQKVKRGKFTMPPEFHPDLKDMIQRMI 244
>UniRef50_A2FMX7 Cluster: CAMK family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 397
Score = 152 bits (368), Expect = 3e-35
Identities = 83/266 (31%), Positives = 144/266 (54%), Gaps = 12/266 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y++ +G GA++ V L + +++ K +ACKI+ ++ + + EI + +L
Sbjct: 14 YQIRGTIGTGAFSVVKL----AYDEARKRYMACKIVPKSRLSSPELEQRFEIEIKIFQQL 69
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP +I ++ + + YYIFM + NG+L +I+ G +SE++ + Q+ L Y+H
Sbjct: 70 THPGIITLYDLLKDDLNYYIFMEFCPNGELFQHIVDEGKLSEDETKTIVYQVFSVLSYIH 129
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
IAHRD+K EN+LL +VK+SDFG SRF Q ++ T CGS YA+PE + G
Sbjct: 130 SKGIAHRDLKPENLLLDEQGHVKISDFGLSRFV----GQTGIANTPCGSPCYASPECVSG 185
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
PY +D+WS GV+++ ML +P+ +L++Q +Y + L+ +C+
Sbjct: 186 CPYNAFTSDVWSTGVIIYAMLTGQLPWTKRNQTQLFQQIRRGEY----TIPKHLTPDCQN 241
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIA 284
++ L+ D R + L+ W+A
Sbjct: 242 FIQGLMTVDITKRLTIEEALNHPWMA 267
Score = 136 bits (330), Expect = 1e-30
Identities = 77/264 (29%), Positives = 135/264 (51%), Gaps = 12/264 (4%)
Query: 325 LEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSH 384
+ G AF V Y A K +ACK++ S +++ EI++ +L+H
Sbjct: 16 IRGTIGTGAFSVVKLAYDEARKR----YMACKIVPKSRLSSPELEQRFEIEIKIFQQLTH 71
Query: 385 PHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHEL 444
P ++ + + + Y+IFM + G+L + ++ G + ED+ + Q+ + Y+H
Sbjct: 72 PGIITLYDLLKDDLNYYIFMEFCPNGELFQHIVDEGKLSEDETKTIVYQVFSVLSYIHSK 131
Query: 445 EIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTP 504
IAHRD+K EN+LL +VK+SDFG +R + + T CGS Y +PE + G P
Sbjct: 132 GIAHRDLKPENLLLDEQGHVKISDFGLSRFVGQTGI----ANTPCGSPCYASPECVSGCP 187
Query: 505 YLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLI 564
Y +DVWS G+++Y ML +P+ ++ QL Q QI + ++ ++ +C+ I
Sbjct: 188 YNAFTSDVWSTGVIIYAMLTGQLPWTKRNQTQLFQ-QIRRGEYTIPKH---LTPDCQNFI 243
Query: 565 GLMLEPNHQNRLKIYDIVNSEWIA 588
++ + RL I + +N W+A
Sbjct: 244 QGLMTVDITKRLTIEEALNHPWMA 267
>UniRef50_A2EZM5 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 379
Score = 152 bits (368), Expect = 3e-35
Identities = 99/273 (36%), Positives = 143/273 (52%), Gaps = 21/273 (7%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKST---LACKIIETAKAPKDFVVKFLPRE 71
L Y+ +GEG ++KVY + HK T +A KII A+ KD L E
Sbjct: 5 LISDYEFQSSIGEGGFSKVY-------QAIHKPTGVRVAVKIIPKAEQAKDKNRIPLRNE 57
Query: 72 IDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLA 131
ID L +++HP + + + Y+ M +NG LL + K + E A + + A
Sbjct: 58 IDALKKVHHPFICRFFDVIESDDYVYLIMECLKNGTLLDEVTKKK-LDERDAAITFAEFA 116
Query: 132 LGLQYLH-ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSY 190
L LQYLH E IAHRDIK ENVLL N N+++ DFGF++ E+D+ +T+CGS+ Y
Sbjct: 117 LALQYLHKEAHIAHRDIKLENVLLDDNHNIRIIDFGFAK---ETDHGNCF-KTHCGSILY 172
Query: 191 AAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVAS 250
AAPE+L G+ Y K D+WS GV+LF+M S PF M ++ + + +F
Sbjct: 173 AAPELLLGEEYTEK-VDIWSAGVMLFIMTTGSFPFYHENMSICLQKIVMSEVQF----PG 227
Query: 251 ILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
LS K ++ +L DP R S VL+ W+
Sbjct: 228 SLSFSLKDLLMRMLTKDPKERISIDQVLEHPWL 260
Score = 120 bits (290), Expect = 9e-26
Identities = 74/236 (31%), Positives = 124/236 (52%), Gaps = 11/236 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I + +D + L EI+ L K+ HP + + + ++ M ++ G L
Sbjct: 35 VAVKIIPKAEQAKDKNRIPLRNEIDALKKVHHPFICRFFDVIESDDYVYLIMECLKNGTL 94
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMH-ELEIAHRDIKCENVLLTANQNVKLSDFGF 471
L+ V ++ + E A I + ALA+QY+H E IAHRDIK ENVLL N N+++ DFGF
Sbjct: 95 LDEVTKK-KLDERDAAITFAEFALALQYLHKEAHIAHRDIKLENVLLDDNHNIRIIDFGF 153
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
A+ +T CGS+ Y APE+L G Y K D+WS G+++++M + PF
Sbjct: 154 AKETDHGNC----FKTHCGSILYAAPELLLGEEYTEK-VDIWSAGVMLFIMTTGSFPFYH 208
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+++ Q + +F ++S + K L+ ML + + R+ I ++ W+
Sbjct: 209 ENMSICLQKIVMSEVQFPG----SLSFSLKDLLMRMLTKDPKERISIDQVLEHPWL 260
>UniRef50_A2E6I9 Cluster: AGC family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 393
Score = 152 bits (368), Expect = 3e-35
Identities = 96/301 (31%), Positives = 169/301 (56%), Gaps = 20/301 (6%)
Query: 10 EENTLLTKG-YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKII--ETAKAPKDFVVK 66
EE T + G Y L + +GEGA++ V+ + SK+ + ST+A K+I +T +AP D +
Sbjct: 4 EEITCIPIGNYILRQRIGEGAFSSVWTAD--SKKTN--STVAVKVISKKTLEAP-DMFTR 58
Query: 67 FLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVW 126
F REI +L + NHP ++H + + + YY+ M Y +NGD +++ + EN +R +
Sbjct: 59 F-KREISLLQQNNHPFIMHFFEMLEDEKNYYVIMEYADNGDFETFLESKMTLPENMSRFF 117
Query: 127 TRQLALGLQYLH-ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYC 185
++ L L YLH E IAHRD+K +N+LL N+++SDFG S SD+ P ++ C
Sbjct: 118 LAEMVLALDYLHNERRIAHRDLKPQNILLDRYNNIRISDFGLSN--TFSDSNPTMTSN-C 174
Query: 186 GSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFR 245
GS ++ APE++ G+PY K D+WSLGV+ + M+ ++PF ++ + + + + +
Sbjct: 175 GSPAFVAPEVVNGQPY-NKSADIWSLGVIFYRMVVGNLPFQGPDVKTILMKIVSAEPYY- 232
Query: 246 SRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKE 305
LS + + +++ +L +P R +A + WI + N+++ +L+ A
Sbjct: 233 ---PPSLSPDLRDLLQKMLCRNPEKRITAKEIKAHPWIIPEFVQELSNSID--SLREATS 287
Query: 306 D 306
D
Sbjct: 288 D 288
Score = 129 bits (312), Expect = 2e-28
Identities = 76/240 (31%), Positives = 127/240 (52%), Gaps = 13/240 (5%)
Query: 351 SILACKVIDTST--APRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYME 408
S +A KVI T AP F + REI +L + +HP ++H + + Y++ M Y +
Sbjct: 38 STVAVKVISKKTLEAPDMFTR--FKREISLLQQNNHPFIMHFFEMLEDEKNYYVIMEYAD 95
Query: 409 RGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMH-ELEIAHRDIKCENVLLTANQNVKLS 467
GD F+ + + E+ +R + ++ LA+ Y+H E IAHRD+K +N+LL N+++S
Sbjct: 96 NGDFETFLESKMTLPENMSRFFLAEMVLALDYLHNERRIAHRDLKPQNILLDRYNNIRIS 155
Query: 468 DFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAM 527
DFG + D N + CGS ++ APE++ G PY K D+WSLG++ Y M+ +
Sbjct: 156 DFGLSNTFSDS--NPTMTSN-CGSPAFVAPEVVNGQPY-NKSADIWSLGVIFYRMVVGNL 211
Query: 528 PFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
PF+ +K + + K Y ++S + + L+ ML N + R+ +I WI
Sbjct: 212 PFQGPDVKTI----LMKIVSAEPYYPPSLSPDLRDLLQKMLCRNPEKRITAKEIKAHPWI 267
>UniRef50_UPI000155CFAD Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 722
Score = 151 bits (367), Expect = 4e-35
Identities = 94/288 (32%), Positives = 156/288 (54%), Gaps = 22/288 (7%)
Query: 3 DLKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKST---LACKIIETAKA 59
+ KT P +T Y + K + +G++AKV E H T +A K+I+ KA
Sbjct: 52 EAKTFP---HTKQVGAYLVGKMINKGSFAKVM-------EGLHLLTGEKVAIKVIDKRKA 101
Query: 60 PKD-FVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCV 118
+D ++++ + RE + + HP+++ ++ + + YY+ M GDLL I +
Sbjct: 102 QEDGYILENMRREPRIQQMIKHPNIVQLYETLETENSYYMVMELCLGGDLLDRIYNKQKL 161
Query: 119 SENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFC-VESDNQ 177
E + + +TRQ+ +++LH I HRD+K EN LL N N+K+ DFG S +E +Q
Sbjct: 162 EEEEVKKFTRQIVSAVEHLHRHGIVHRDLKIENFLLDENSNIKIIDFGLSNILKLEGLSQ 221
Query: 178 PVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF--DDTRMRKLYE 235
+L+ T CGS +YAAPE+L K Y PK D+WS+GV +F ML ++PF D +++L++
Sbjct: 222 ELLN-TQCGSPAYAAPELLAHKKYGPK-VDVWSIGVSMFAMLTGTLPFTVDPFNIKQLHQ 279
Query: 236 QQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ + + S V +S + LLEPDPG R + + +W+
Sbjct: 280 KMINGEV---SSVPPGISSGAVHFMHSLLEPDPGKRPAIKEAMKDKWL 324
Score = 140 bits (339), Expect = 1e-31
Identities = 78/238 (32%), Positives = 129/238 (54%), Gaps = 7/238 (2%)
Query: 353 LACKVIDTSTAPRD-FVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A KVID A D ++ + + RE + + HP++V + + Y++ M GD
Sbjct: 91 VAIKVIDKRKAQEDGYILENMRREPRIQQMIKHPNIVQLYETLETENSYYMVMELCLGGD 150
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
LL+ + + ++E++ + +TRQ+ A++++H I HRD+K EN LL N N+K+ DFG
Sbjct: 151 LLDRIYNKQKLEEEEVKKFTRQIVSAVEHLHRHGIVHRDLKIENFLLDENSNIKIIDFGL 210
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF-- 529
+ + + L++ T CGS +Y APE+L Y PK DVWS+G+ ++ ML +PF
Sbjct: 211 SNILKLEGLSQELLNTQCGSPAYAAPELLAHKKYGPK-VDVWSIGVSMFAMLTGTLPFTV 269
Query: 530 EDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ +IKQLHQ IN S IS + +LEP+ R I + + +W+
Sbjct: 270 DPFNIKQLHQKMINGE---VSSVPPGISSGAVHFMHSLLEPDPGKRPAIKEAMKDKWL 324
>UniRef50_Q4SW69 Cluster: Chromosome 9 SCAF13686, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 9
SCAF13686, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1143
Score = 151 bits (367), Expect = 4e-35
Identities = 87/248 (35%), Positives = 133/248 (53%), Gaps = 11/248 (4%)
Query: 342 RNASKNDKLSI--LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYK 399
R A+ +D + +A K I D + + REIE+ L H +++ H +F+ R K
Sbjct: 586 RRAAMHDSYDVCLVAIKSIRKERIVEDLDRVHIQREIEITASLRHANIIRFHEVFESRDK 645
Query: 400 YFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLT 459
I M Y RG+L ++VL+R + E +AR RQ+ A+ Y H++ + HRD+K EN+LL
Sbjct: 646 IVIVMEYASRGELYDYVLERRRLSETEARGIFRQITSAVHYCHKIGVVHRDLKLENILLD 705
Query: 460 ANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVV 519
+ NVKL+DFG + L +T+CGS Y APEI++G PY D W+LG+++
Sbjct: 706 EDLNVKLADFGLSNHFKRGSL----LQTYCGSPLYAAPEIVKGLPYQGPEVDCWALGVLL 761
Query: 520 YVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIY 579
Y ++ +MPF+ L + QI K R R + SD C LI +L + R I
Sbjct: 762 YALVYSSMPFDGASHTMLTE-QITKG---RYRRPNPPSDAC-ALIDWLLTVRVEERATIE 816
Query: 580 DIVNSEWI 587
D+ N W+
Sbjct: 817 DVANHWWV 824
Score = 150 bits (364), Expect = 1e-34
Identities = 78/206 (37%), Positives = 114/206 (55%), Gaps = 5/206 (2%)
Query: 39 SSKEDSHKSTL-ACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYY 97
++ DS+ L A K I + +D + REI++ L H ++I H +F+ + K
Sbjct: 588 AAMHDSYDVCLVAIKSIRKERIVEDLDRVHIQREIEITASLRHANIIRFHEVFESRDKIV 647
Query: 98 IFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTAN 157
I M Y G+L Y+L+ +SE +AR RQ+ + Y H++ + HRD+K EN+LL +
Sbjct: 648 IVMEYASRGELYDYVLERRRLSETEARGIFRQITSAVHYCHKIGVVHRDLKLENILLDED 707
Query: 158 FNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFV 217
NVKL+DFG S L +TYCGS YAAPEI++G PY D W+LGV+L+
Sbjct: 708 LNVKLADFGLSNHFKRGS----LLQTYCGSPLYAAPEIVKGLPYQGPEVDCWALGVLLYA 763
Query: 218 MLNKSMPFDDTRMRKLYEQQMGKKYR 243
++ SMPFD L EQ +YR
Sbjct: 764 LVYSSMPFDGASHTMLTEQITKGRYR 789
>UniRef50_Q4QIJ7 Cluster: Serine/threonine kinase, putative; n=13;
Trypanosomatidae|Rep: Serine/threonine kinase, putative
- Leishmania major
Length = 296
Score = 151 bits (367), Expect = 4e-35
Identities = 87/268 (32%), Positives = 139/268 (51%), Gaps = 8/268 (2%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L + +G G ++KV + +++ A K+I+ + ++ + + L REI V+ L
Sbjct: 10 YELGRTLGTGNFSKVKI----ARDTETGKEWAIKVIDKEQLVRERMEEQLKREIAVMKML 65
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
P++I +H + Q Y+ + G+L I E AR + QL G+ Y H
Sbjct: 66 RQPNIIELHEVMQTSHHIYLVLELVTGGELFEKIASAKRFDEPTARHYFHQLICGINYCH 125
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
IAHRD+K EN+LL AN +K+SDFG S S + + +T CG+ +Y APE+L+
Sbjct: 126 RQGIAHRDLKPENLLLDANDTLKISDFGLSNLQRTSVSGGTMLQTVCGTPNYVAPEVLKE 185
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y D+WS GVVLFVM+ +PFDD + L+ K R R+A S + +
Sbjct: 186 QGYDGLKADIWSCGVVLFVMMAGYLPFDDENVNALFT----KIERGEFRMARHFSADARD 241
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMD 286
++ +L DP R S +V+ W +D
Sbjct: 242 LISRMLTVDPQERISLDDVIAHPWFCVD 269
Score = 138 bits (334), Expect = 4e-31
Identities = 74/237 (31%), Positives = 122/237 (51%), Gaps = 4/237 (1%)
Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLL 413
A KVID R+ +++ L REI ++ L P+++ H + Q + ++ + + G+L
Sbjct: 37 AIKVIDKEQLVRERMEEQLKREIAVMKMLRQPNIIELHEVMQTSHHIYLVLELVTGGELF 96
Query: 414 EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFAR 473
E + E AR + QL I Y H IAHRD+K EN+LL AN +K+SDFG +
Sbjct: 97 EKIASAKRFDEPTARHYFHQLICGINYCHRQGIAHRDLKPENLLLDANDTLKISDFGLSN 156
Query: 474 MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKH 533
+ +T CG+ +Y APE+L+ Y D+WS G+V++VM+ +PF+D++
Sbjct: 157 LQRTSVSGGTMLQTVCGTPNYVAPEVLKEQGYDGLKADIWSCGVVLFVMMAGYLPFDDEN 216
Query: 534 IKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
+ L K + R S + + LI ML + Q R+ + D++ W +D
Sbjct: 217 VNAL----FTKIERGEFRMARHFSADARDLISRMLTVDPQERISLDDVIAHPWFCVD 269
>UniRef50_A2FDI8 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 407
Score = 151 bits (367), Expect = 4e-35
Identities = 88/279 (31%), Positives = 144/279 (51%), Gaps = 12/279 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
YKL + +G G+++KV E + + + K A K+I ++ + K L REI+++ ++
Sbjct: 8 YKLLRTIGAGSFSKV--KEAINTKTNKK--YAIKVINRQLVAQNNMDKQLRREIEIMSQM 63
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP LI +H++ ++ + G+L S + NG + E +AR + +QL L Y+H
Sbjct: 64 DHPGLIKLHAVMHSTENIFLVLDLATGGELFSKLADNGPLPEKKARKYFQQLIDALDYMH 123
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ HRD+K EN+LL + N+K++DFG S D T CG+ +Y APEI
Sbjct: 124 KHNAVHRDLKPENILLDNDENLKIADFGLSIMSSAGDT----CYTRCGTPNYVAPEIFCQ 179
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y P D+WS GV+LFVML+ S+PFD ++ L Q M + + S
Sbjct: 180 DGYIGAPADIWSAGVILFVMLSASLPFDAPNLQNLARQIMNVRLEY----PSYFPAGAVA 235
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEA 297
++K +L DP R + + W A D T + ++A
Sbjct: 236 LMKKILVADPSTRATMEQIKADPWFATDYVPVTSSTIQA 274
Score = 126 bits (305), Expect = 1e-27
Identities = 86/304 (28%), Positives = 152/304 (50%), Gaps = 17/304 (5%)
Query: 318 PKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIE 377
PK GD T + + E N N K +I KVI+ ++ + K L REIE
Sbjct: 2 PKTVGDYKLLRTIGAGSFSKVKEAINTKTNKKYAI---KVINRQLVAQNNMDKQLRREIE 58
Query: 378 MLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALA 437
++ ++ HP L+ H++ F+ + G+L + G + E +AR + +QL A
Sbjct: 59 IMSQMDHPGLIKLHAVMHSTENIFLVLDLATGGELFSKLADNGPLPEKKARKYFQQLIDA 118
Query: 438 IQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAP 497
+ YMH+ HRD+K EN+LL ++N+K++DFG + M T CG+ +Y AP
Sbjct: 119 LDYMHKHNAVHRDLKPENILLDNDENLKIADFGLSIMSSAGD----TCYTRCGTPNYVAP 174
Query: 498 EILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTIS 557
EI Y+ P D+WS G++++VML+ ++PF+ +++ L + +N ++ S +
Sbjct: 175 EIFCQDGYIGAPADIWSAGVILFVMLSASLPFDAPNLQNLARQIMNVRLEYPSYFPAGAV 234
Query: 558 DNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD-----SRLLEWTP-QETLAYKKAREEK 611
K++ L+ +P+ R + I W A D S ++ T E ++ KK +E+
Sbjct: 235 ALMKKI--LVADPS--TRATMEQIKADPWFATDYVPVTSSTIQATKVDEEVSVKKDEQEE 290
Query: 612 NKLH 615
++
Sbjct: 291 ESIN 294
>UniRef50_Q59W62 Cluster: Likely protein kinase; n=2; Candida
albicans|Rep: Likely protein kinase - Candida albicans
(Yeast)
Length = 1349
Score = 151 bits (367), Expect = 4e-35
Identities = 91/264 (34%), Positives = 147/264 (55%), Gaps = 12/264 (4%)
Query: 19 YKLTKFVGEGAYAKVYL-TEYSSKEDSHKSTLACKIIETAKAPK--DFVVKFLPREIDVL 75
+KL K +G GA +V L T ++ + + ++ ++ + K D + + REI ++
Sbjct: 28 WKLGKTLGRGATGRVLLATHQTTGQKAAVKVVSKSELQDEETEKNGDGLPYGIEREIIIM 87
Query: 76 VRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQ 135
L HP+++ ++ +++ Y+ + Y E G+L +++ G + E +A + RQ+ LG
Sbjct: 88 KLLTHPNVLRLYDVWETSKALYLVLEYVEGGELFDLLVERGPLPEVEAIKYFRQIILGTA 147
Query: 136 YLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEI 195
Y H L I HRD+K EN+LL + NVKL+DFG + +ES+ + L ET CGS YAAPEI
Sbjct: 148 YCHALGICHRDLKPENLLLDSQLNVKLADFGMA--ALESNGK--LLETSCGSPHYAAPEI 203
Query: 196 LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRK-LYEQQMGKKYRFRSRVASILSL 254
+ G Y +D+WS GV+LF +L +PFDD +R L + Q G F V + S
Sbjct: 204 VSGLKYHGAASDVWSCGVILFALLTGRLPFDDENIRNLLLKVQAG---NFEMPVDEV-SR 259
Query: 255 ECKTVVKHLLEPDPGLRHSATNVL 278
E + ++ +LE DP R S +L
Sbjct: 260 EARDLIARMLEVDPMRRISTEKIL 283
Score = 140 bits (340), Expect = 8e-32
Identities = 87/273 (31%), Positives = 148/273 (54%), Gaps = 12/273 (4%)
Query: 314 HKHPPKRQGDILEGPT--RESAFRVYLAEYRNASKNDKLSILA-CKVIDTSTAPR-DFVK 369
H HP K G G T R + RV LA ++ + + +++ ++ D T D +
Sbjct: 19 HNHPQKI-GPWKLGKTLGRGATGRVLLATHQTTGQKAAVKVVSKSELQDEETEKNGDGLP 77
Query: 370 KFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARI 429
+ REI ++ L+HP+++ + +++ ++ + Y+E G+L + +++RG + E +A
Sbjct: 78 YGIEREIIIMKLLTHPNVLRLYDVWETSKALYLVLEYVEGGELFDLLVERGPLPEVEAIK 137
Query: 430 WTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFC 489
+ RQ+ L Y H L I HRD+K EN+LL + NVKL+DFG A + + KL ET C
Sbjct: 138 YFRQIILGTAYCHALGICHRDLKPENLLLDSQLNVKLADFGMAALESNGKL----LETSC 193
Query: 490 GSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFR 549
GS Y APEI+ G Y +DVWS G++++ +L +PF+D++I+ L N++
Sbjct: 194 GSPHYAAPEIVSGLKYHGAASDVWSCGVILFALLTGRLPFDDENIRNLLLKVQAGNFEMP 253
Query: 550 SRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIV 582
+D +S + LI MLE + R+ I+
Sbjct: 254 ---VDEVSREARDLIARMLEVDPMRRISTEKIL 283
>UniRef50_UPI0000660272 Cluster: Homolog of Homo sapiens
"MAP/microtubule affinity-regulating kinase 2; n=1;
Takifugu rubripes|Rep: Homolog of Homo sapiens
"MAP/microtubule affinity-regulating kinase 2 - Takifugu
rubripes
Length = 760
Score = 151 bits (366), Expect = 6e-35
Identities = 88/287 (30%), Positives = 157/287 (54%), Gaps = 23/287 (8%)
Query: 4 LKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEY--SSKEDSHKSTLACKIIETAKAPK 61
+ TT SE+ + Y+L K +G+G +AKV L + + KE +A KII+ +
Sbjct: 24 VSTTTSEDQPHIGN-YRLLKTIGKGNFAKVKLARHVLTGKE------VAVKIIDKTQLNS 76
Query: 62 DFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSEN 121
+ K RE+ ++ LNHP+++ + + + + Y+ M Y G++ Y++ +G + E
Sbjct: 77 SSLQKLF-REVRIMKLLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEK 135
Query: 122 QARVWTRQL-ALGLQYL----HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDN 176
+AR RQ+ + G + H+ + D+ EN+LL A+ N+K++DFGFS +
Sbjct: 136 EARAKFRQVGSRGTVRVNPSPHKYRNTYIDVCAENLLLDADMNIKIADFGFSNEFTLGNK 195
Query: 177 QPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ 236
+T+CGS YAAPE+ +GK Y D+WSLGV+L+ +++ S+PFD +++L E+
Sbjct: 196 L----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRER 251
Query: 237 QMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ KY R+ +S +C+ ++K L +P R S ++ W+
Sbjct: 252 VLRGKY----RIPFYMSTDCENLLKKFLILNPSKRGSLEQIMRDRWM 294
Score = 121 bits (291), Expect = 7e-26
Identities = 68/241 (28%), Positives = 129/241 (53%), Gaps = 16/241 (6%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID + ++K RE+ ++ L+HP++V + + ++ M Y G++
Sbjct: 64 VAVKIIDKTQLNSSSLQKLF-REVRIMKLLNHPNIVKLFEVIETEKTLYLVMEYASGGEV 122
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYM-----HELEIAHRDIKCENVLLTANQNVKLS 467
++++ G ++E +AR RQ+ H+ + D+ EN+LL A+ N+K++
Sbjct: 123 FDYLVAHGRMKEKEARAKFRQVGSRGTVRVNPSPHKYRNTYIDVCAENLLLDADMNIKIA 182
Query: 468 DFGFAR-MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRA 526
DFGF+ + KL +TFCGS Y APE+ QG Y DVWSLG+++Y +++ +
Sbjct: 183 DFGFSNEFTLGNKL-----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGS 237
Query: 527 MPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+PF+ +++K+L + + K+R + +S +C+ L+ L N R + I+ W
Sbjct: 238 LPFDGQNLKELRERVL--RGKYRIPFY--MSTDCENLLKKFLILNPSKRGSLEQIMRDRW 293
Query: 587 I 587
+
Sbjct: 294 M 294
>UniRef50_Q6BG36 Cluster: SNF1-related protein kinase, putative;
n=2; Oligohymenophorea|Rep: SNF1-related protein kinase,
putative - Paramecium tetraurelia
Length = 422
Score = 151 bits (366), Expect = 6e-35
Identities = 87/274 (31%), Positives = 145/274 (52%), Gaps = 12/274 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G G + V L + + +A KI+E + + V+ + REI +L +
Sbjct: 28 YQLVKTLGVGTFGLVKLGLHQITGEK----VAIKILEKERIVEVADVERVSREIHILKLI 83
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
H H+I ++ I + K ++ M + + G+L YI+KN + E +A ++L G++Y+H
Sbjct: 84 RHRHVIQLYEIIETKKHIFLVMEFCDKGELFDYIVKNDKLDEIEACRIFQELISGIEYIH 143
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+L I HRD+K EN+LL +K+ DFG S + Q L +T CGS YAAPE++ G
Sbjct: 144 KLNIVHRDLKPENLLLDHQNQIKIVDFGLS----NTYKQGELLKTACGSPCYAAPEMIAG 199
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y D+WS GV+LF + +PF+D LY++ +G +Y S V S + ++
Sbjct: 200 HRYQSILVDIWSCGVILFATICGQLPFEDKNTSDLYKKILGGQYTIPSHV----SQDGQS 255
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTL 292
+K LL DP R + + W + R+ ++
Sbjct: 256 FLKGLLNTDPSKRFNLEQIKQHPWFKLYKRVQSI 289
Score = 115 bits (277), Expect = 3e-24
Identities = 59/220 (26%), Positives = 113/220 (51%), Gaps = 8/220 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
REI +L + H H++ + I + + F+ M + ++G+L +++++ + E +A ++
Sbjct: 75 REIHILKLIRHRHVIQLYEIIETKKHIFLVMEFCDKGELFDYIVKNDKLDEIEACRIFQE 134
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
L I+Y+H+L I HRD+K EN+LL +K+ DFG + +L +T CGS
Sbjct: 135 LISGIEYIHKLNIVHRDLKPENLLLDHQNQIKIVDFGLSNTYKQGEL----LKTACGSPC 190
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y APE++ G Y D+WS G++++ + +PFEDK+ L++ + + S
Sbjct: 191 YAAPEMIAGHRYQSILVDIWSCGVILFATICGQLPFEDKNTSDLYKKILGGQYTIPSH-- 248
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRL 593
+S + + + +L + R + I W + R+
Sbjct: 249 --VSQDGQSFLKGLLNTDPSKRFNLEQIKQHPWFKLYKRV 286
>UniRef50_A2ET53 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 424
Score = 151 bits (366), Expect = 6e-35
Identities = 91/314 (28%), Positives = 157/314 (50%), Gaps = 13/314 (4%)
Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84
+GEGA++ V L ++ + ACKII AK +F EI + ++ HP ++
Sbjct: 22 IGEGAFSIVKLVV----KEQNGQYYACKIIPRAKLEGSIRTRF-ELEIRINQQMRHPGVV 76
Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144
+ +F+ YYI M + NG+L YI+++G +SE + + QL +Q++H + + H
Sbjct: 77 ALIDLFKDDFNYYIIMEFCPNGELFEYIVQHGKLSERECKPLFYQLTSTIQFIHNMNVCH 136
Query: 145 RDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPK 204
RD+K EN+L+ +K+SDFG SRF + T CGS YA+PE + GKPY K
Sbjct: 137 RDLKPENILIDRFGRLKISDFGLSRFM----GPNCIVSTSCGSPCYASPECISGKPYNAK 192
Query: 205 PTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLL 264
+D+WSLGV+ + M + +P+ +LY+Q Y+ + ++ L+ +V+ +L
Sbjct: 193 TSDVWSLGVIFYAMSSGLLPWTKRNQTELYQQISTGDYKIPNHLSPALA----DLVRKML 248
Query: 265 EPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKEDRRKLSDVHKHPPKRQGDI 324
D R + +LD ++ ++ + + K D+ D + K D
Sbjct: 249 TVDLNKRITIAQILDHDFFKDINKQVVYPPLNVPLVSLKKIDQFFERDKEEQYRKDHPDE 308
Query: 325 LEGPTRESAFRVYL 338
T +++FR L
Sbjct: 309 FSSSTGDNSFRKQL 322
Score = 132 bits (319), Expect = 3e-29
Identities = 82/282 (29%), Positives = 142/282 (50%), Gaps = 14/282 (4%)
Query: 318 PKRQGD-ILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREI 376
P R GD I +G E AF + + K ACK+I + +F EI
Sbjct: 10 PNRIGDFIFKGTIGEGAFSIV----KLVVKEQNGQYYACKIIPRAKLEGSIRTRF-ELEI 64
Query: 377 EMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLAL 436
+ ++ HP +V +F+ + Y+I M + G+L E+++Q G + E + + QL
Sbjct: 65 RINQQMRHPGVVALIDLFKDDFNYYIIMEFCPNGELFEYIVQHGKLSERECKPLFYQLTS 124
Query: 437 AIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTA 496
IQ++H + + HRD+K EN+L+ +K+SDFG +R N I S T CGS Y +
Sbjct: 125 TIQFIHNMNVCHRDLKPENILIDRFGRLKISDFGLSRFMGP---NCIVS-TSCGSPCYAS 180
Query: 497 PEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTI 556
PE + G PY K +DVWSLG++ Y M + +P+ ++ +L+Q ++K + +
Sbjct: 181 PECISGKPYNAKTSDVWSLGVIFYAMSSGLLPWTKRNQTELYQQISTGDYKIPNHLSPAL 240
Query: 557 SDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLLEWTP 598
+D L+ ML + R+ I I++ ++ ++ + + P
Sbjct: 241 AD----LVRKMLTVDLNKRITIAQILDHDFFKDINKQVVYPP 278
>UniRef50_A2DBR9 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 496
Score = 151 bits (366), Expect = 6e-35
Identities = 79/217 (36%), Positives = 129/217 (59%), Gaps = 12/217 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKII--ETAKAPKDFVVKFLPREIDVLV 76
Y L + +G G+ +K+ L + K +A KII ++ K K + REI ++
Sbjct: 11 YMLVRNLGSGSTSKIKLAIHQET----KMPVAIKIIKKDSFKDNPQLQPK-IQREIALMR 65
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
+HPH++ + I + YI + Y +G+L +Y+++N +SE A + RQ+ GL+Y
Sbjct: 66 LFDHPHILKLLDILESPRHLYIGLEYASHGELFTYVVENKQISEQAAMRFFRQIIYGLEY 125
Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
LH L I HRD+K EN+LL +N+K++DFGF+RF ++ ++ET CGS Y APE++
Sbjct: 126 LHSLGICHRDLKPENILLDDKYNIKIADFGFARFTKKN-----VAETSCGSPHYVAPEVI 180
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKL 233
G+ Y + D+WS GV+L+ +L ++PFDD +R L
Sbjct: 181 GGEVYDGRCADVWSCGVILYALLTGNLPFDDPSIRNL 217
Score = 131 bits (316), Expect = 7e-29
Identities = 73/210 (34%), Positives = 115/210 (54%), Gaps = 10/210 (4%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ REI ++ HPH++ I + +I + Y G+L +V++ + E A +
Sbjct: 57 IQREIALMRLFDHPHILKLLDILESPRHLYIGLEYASHGELFTYVVENKQISEQAAMRFF 116
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
RQ+ ++Y+H L I HRD+K EN+LL N+K++DFGFAR K N +ET CGS
Sbjct: 117 RQIIYGLEYLHSLGICHRDLKPENILLDDKYNIKIADFGFARF---TKKNV--AETSCGS 171
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y APE++ G Y + DVWS G+++Y +L +PF+D I+ L A++ + F
Sbjct: 172 PHYVAPEVIGGEVYDGRCADVWSCGVILYALLTGNLPFDDPSIRNL-LAKVRRG-VFT-- 227
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKIYDI 581
+ +SD K LI ML + + R+ I I
Sbjct: 228 -MPDVSDPLKDLISKMLTKDPKQRITIRQI 256
>UniRef50_Q6CAK0 Cluster: Yarrowia lipolytica chromosome D of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome D of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 579
Score = 151 bits (366), Expect = 6e-35
Identities = 84/264 (31%), Positives = 144/264 (54%), Gaps = 13/264 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y++ K +GEG++ KV L + + + +A KII K + + REI L L
Sbjct: 31 YQIIKTLGEGSFGKVKLAYHLATHEK----VALKIINRKTLAKSDMQGRVEREISYLRLL 86
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++ + + K + + + + +L YI++ G + E++AR + +Q+ ++Y H
Sbjct: 87 RHPHIIKLYDVIKSKDEIIMVIEFAGK-ELFDYIVQRGKMPEDEARRFFQQIISAVEYCH 145
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+I HRD+K EN+LL N NVK++DFG S + + +T CGS +YAAPE++ G
Sbjct: 146 RHKIVHRDLKPENLLLDENLNVKIADFGLSNIMTDGN----FLKTSCGSPNYAAPEVISG 201
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS GV+L+VML +PFDD + L+++ Y + LS K
Sbjct: 202 KLYAGPEVDVWSCGVILYVMLCGRLPFDDEFIPNLFKKISNGVY----TIPPYLSAGAKH 257
Query: 259 VVKHLLEPDPGLRHSATNVLDSEW 282
+++ +L +P R + +++ W
Sbjct: 258 LLQQMLVVNPLNRITVQGIMEDPW 281
Score = 145 bits (351), Expect = 4e-33
Identities = 76/234 (32%), Positives = 130/234 (55%), Gaps = 9/234 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I+ T + ++ + REI L L HPH++ + + + + + + + + + +L
Sbjct: 57 VALKIINRKTLAKSDMQGRVEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEFAGK-EL 115
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++QRG + ED+AR + +Q+ A++Y H +I HRD+K EN+LL N NVK++DFG +
Sbjct: 116 FDYIVQRGKMPEDEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDENLNVKIADFGLS 175
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ D +T CGS +Y APE++ G Y DVWS G+++YVML +PF+D+
Sbjct: 176 NIMTDGNF----LKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCGRLPFDDE 231
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
I L + N + +S K L+ ML N NR+ + I+ W
Sbjct: 232 FIPNLFKKISNGVYTIP----PYLSAGAKHLLQQMLVVNPLNRITVQGIMEDPW 281
>UniRef50_Q9VUV4 Cluster: CG6114-PA; n=2; Drosophila
melanogaster|Rep: CG6114-PA - Drosophila melanogaster
(Fruit fly)
Length = 861
Score = 151 bits (365), Expect = 8e-35
Identities = 83/275 (30%), Positives = 147/275 (53%), Gaps = 17/275 (6%)
Query: 11 ENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR 70
EN Y+L K +G+G V L + +A KII K + ++K + R
Sbjct: 10 ENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKK----VAIKIINREKLSESVLMK-VER 64
Query: 71 EIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQL 130
EI ++ ++HPH++ + +++ K Y+ + + G+L Y++K G ++ +AR + RQ+
Sbjct: 65 EIAIMKLIDHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQI 124
Query: 131 ALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPV--LSETYCGSM 188
L + H I HRD+K EN+LL N+K++DFG + QP + ET CGS
Sbjct: 125 ISALDFCHSHSICHRDLKPENLLLDEKNNIKIADFGMASL------QPAGSMLETSCGSP 178
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
YA PE++RG+ Y + D+WS GV+L+ +L ++PFDD +R+L E K R +
Sbjct: 179 HYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLE----KVKRGVFHI 234
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ +C+++++ ++E +P R + + W+
Sbjct: 235 PHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWV 269
Score = 136 bits (328), Expect = 2e-30
Identities = 68/235 (28%), Positives = 130/235 (55%), Gaps = 9/235 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I+ + K + REI ++ + HPH++ +++ + ++ + ++ G+L
Sbjct: 44 VAIKIINREKLSESVLMK-VEREIAIMKLIDHPHVLGLSDVYENKKYLYLILEHVSGGEL 102
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++++G + +AR + RQ+ A+ + H I HRD+K EN+LL N+K++DFG A
Sbjct: 103 FDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIKIADFGMA 162
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ + ET CGS Y PE+++G Y + DVWS G+++Y +L A+PF+D
Sbjct: 163 SLQPAGSM----LETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDD 218
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+++QL + K F + + +C+ L+ M+E N RL + +I W+
Sbjct: 219 NLRQLLEKV--KRGVFHIPHF--VPPDCQSLLRGMIEVNPDRRLTLAEINRHPWV 269
>UniRef50_Q3LDS4 Cluster: Carbon catabolite derepressing protein
kinase; n=4; Eukaryota|Rep: Carbon catabolite
derepressing protein kinase - Nyctotherus ovalis
Length = 252
Score = 150 bits (364), Expect = 1e-34
Identities = 88/257 (34%), Positives = 136/257 (52%), Gaps = 12/257 (4%)
Query: 4 LKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDF 63
LK E N Y L + +GEG + KV + + + +A KI+E +
Sbjct: 5 LKELSGESNKKSIGQYILGRTLGEGTFGKVRIATHILTGEK----VAIKILEKDRVTDVS 60
Query: 64 VVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQA 123
V+ + REI +L + HP+LI ++ I + + Y+ Y G+L YI+ N + E++A
Sbjct: 61 DVERVAREIHILKIIRHPNLIQLYEIVETTKQLYLVTEYATGGELYEYIVSNTRLEESEA 120
Query: 124 RVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSET 183
+Q+ G++Y+H+L I HRD+K EN+LL ++ N+KL DFG S + Q +T
Sbjct: 121 CRLFQQIISGIEYIHKLRIVHRDLKPENLLLDSSKNIKLGDFGLS----NTYKQDEKLKT 176
Query: 184 YCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYR 243
CGS YAAPE++ GK Y D+WS GVVLF +L +PF+D LY++ + Y
Sbjct: 177 ACGSPCYAAPEMIAGKKYNGLQVDIWSAGVVLFALLCGHLPFEDPNTGNLYKKILNGDY- 235
Query: 244 FRSRVASILSLECKTVV 260
+ LS E K +V
Sbjct: 236 ---NIPKYLSNEAKEIV 249
Score = 120 bits (289), Expect = 1e-25
Identities = 59/174 (33%), Positives = 103/174 (59%), Gaps = 6/174 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
REI +L + HP+L+ + I + + ++ Y G+L E+++ ++E +A +Q
Sbjct: 67 REIHILKIIRHPNLIQLYEIVETTKQLYLVTEYATGGELYEYIVSNTRLEESEACRLFQQ 126
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMC-VDKKLNEIRSETFCGSL 492
+ I+Y+H+L I HRD+K EN+LL +++N+KL DFG + D+KL +T CGS
Sbjct: 127 IISGIEYIHKLRIVHRDLKPENLLLDSSKNIKLGDFGLSNTYKQDEKL-----KTACGSP 181
Query: 493 SYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNW 546
Y APE++ G Y D+WS G+V++ +L +PFED + L++ +N ++
Sbjct: 182 CYAAPEMIAGKKYNGLQVDIWSAGVVLFALLCGHLPFEDPNTGNLYKKILNGDY 235
>UniRef50_O61298 Cluster: HrPOPK-1 protein; n=2; Coelomata|Rep:
HrPOPK-1 protein - Halocynthia roretzi (Sea squirt)
Length = 698
Score = 150 bits (364), Expect = 1e-34
Identities = 81/265 (30%), Positives = 139/265 (52%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
YKL K +G+G V L + +A KI+ K + + K + REI ++ +
Sbjct: 14 YKLEKTLGKGQTGLVKLGVHCMTGKK----VAVKIVNREKLSESVINK-VEREIAIMKLI 68
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH++ +H +++ K Y+ + G+L Y+++ G + +AR + RQ+ + Y H
Sbjct: 69 EHPHILGLHDVYENKKYLYLILELVSGGELFDYLVQKGRLIPREARRFFRQIISAVDYCH 128
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ HRD+K EN+LL N+K++DFG + E L ET CGS YA PE++RG
Sbjct: 129 NHNVCHRDLKPENLLLDEKNNIKVADFGMASLQPEG----FLLETSCGSPHYACPEVIRG 184
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y + D+WS GV+LF +L ++PFDD +R+L E+ Y + + + +
Sbjct: 185 ERYDGRTADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVY----HIPHFVPPDAQN 240
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
+++ +++ P R S VL W+
Sbjct: 241 LLRGMIDVRPDKRLSLQQVLQHPWM 265
Score = 135 bits (326), Expect = 4e-30
Identities = 66/243 (27%), Positives = 133/243 (54%), Gaps = 9/243 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ + K + REI ++ + HPH++ H +++ + ++ + + G+L
Sbjct: 40 VAVKIVNREKLSESVINK-VEREIAIMKLIEHPHILGLHDVYENKKYLYLILELVSGGEL 98
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++Q+G + +AR + RQ+ A+ Y H + HRD+K EN+LL N+K++DFG A
Sbjct: 99 FDYLVQKGRLIPREARRFFRQIISAVDYCHNHNVCHRDLKPENLLLDEKNNIKVADFGMA 158
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ + L ET CGS Y PE+++G Y + DVWS G++++ +L A+PF+D
Sbjct: 159 SLQPEGFL----LETSCGSPHYACPEVIRGERYDGRTADVWSCGVILFALLVGALPFDDD 214
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSR 592
+++QL + ++ + ++ + N L+ M++ RL + ++ W+ S
Sbjct: 215 NLRQLLE-KVKRGVYHIPHFVPPDAQN---LLRGMIDVRPDKRLSLQQVLQHPWMRPGSN 270
Query: 593 LLE 595
+E
Sbjct: 271 SVE 273
>UniRef50_A2EZM7 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 370
Score = 150 bits (364), Expect = 1e-34
Identities = 90/270 (33%), Positives = 140/270 (51%), Gaps = 14/270 (5%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
L + Y++ +GEG Y+KV + E + +A KII + FL +EI +
Sbjct: 6 LLRDYEIKSTLGEGEYSKVCFAIHKPTE----TNVAIKIIRKTSIDTMKIEYFLNKEICI 61
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
+ HP + + F+ YI M Y G LL I K+G ++E A + +L L +
Sbjct: 62 MKEAVHPFICRFYEAFESDLFIYIVMEYISGGTLLDEIYKSGKMNERDASIIFSELMLAI 121
Query: 135 QYLHE-LEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAP 193
YLH+ AHRDIK EN+LL N N++L DFGFS DN L T CGS+ YAAP
Sbjct: 122 SYLHKHCHAAHRDIKAENILLDENHNIRLIDFGFSNL-FSKDN---LMTTQCGSIYYAAP 177
Query: 194 EILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILS 253
E++ G+ Y K D+WS G++L++++ S PF D + L ++ + + S LS
Sbjct: 178 ELIVGQEYTEK-IDVWSAGILLYLLVTGSFPFSDFGVTNLAQKIVYDDIVYPSH----LS 232
Query: 254 LECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
L+ K ++ +L +P R + +L +W+
Sbjct: 233 LQVKDLISRMLIRNPKERITVDEILSHQWV 262
Score = 132 bits (320), Expect = 2e-29
Identities = 78/236 (33%), Positives = 127/236 (53%), Gaps = 10/236 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I ++ ++ FL +EI ++ + HP + + F+ +I M Y+ G L
Sbjct: 36 VAIKIIRKTSIDTMKIEYFLNKEICIMKEAVHPFICRFYEAFESDLFIYIVMEYISGGTL 95
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHE-LEIAHRDIKCENVLLTANQNVKLSDFGF 471
L+ + + G + E A I +L LAI Y+H+ AHRDIK EN+LL N N++L DFGF
Sbjct: 96 LDEIYKSGKMNERDASIIFSELMLAISYLHKHCHAAHRDIKAENILLDENHNIRLIDFGF 155
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+ + L T CGS+ Y APE++ G Y K DVWS GI++Y+++ + PF D
Sbjct: 156 SNLFSKDNL----MTTQCGSIYYAAPELIVGQEYTEK-IDVWSAGILLYLLVTGSFPFSD 210
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ L Q + + + S +S K LI ML N + R+ + +I++ +W+
Sbjct: 211 FGVTNLAQKIVYDDIVYPSH----LSLQVKDLISRMLIRNPKERITVDEILSHQWV 262
>UniRef50_A2DP40 Cluster: CAMK family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 374
Score = 150 bits (364), Expect = 1e-34
Identities = 84/267 (31%), Positives = 136/267 (50%), Gaps = 12/267 (4%)
Query: 17 KGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLV 76
KGY +G GA+AKVY E + K A K+ + + +K REID
Sbjct: 13 KGYTFLTRLGAGAFAKVYKVEQTET----KKVFAIKVFPKSNLKDNDDIKRFQREIDTTA 68
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
L H +++++H F + +Y+ + Y +NG+L+ YI KN ++E A + Q+ + Y
Sbjct: 69 NLKHDNIVNMHDFFSDENNFYLVLDYCQNGELMDYIAKNKRIAEPTAALIFEQIVAAVAY 128
Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
H +AHRD K ENVL +VK+SDFG + S + T+CGS Y+APE L
Sbjct: 129 CHSFGVAHRDFKPENVLFERFPHVKVSDFGLCGYMETSK----MMTTFCGSPCYSAPECL 184
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
K Y + +D+WSLGV L++M+ P++ + + + + Y +V +S EC
Sbjct: 185 YHKAYDGQKSDIWSLGVNLYLMVTGKHPWNISNINVMMRDIVTCNY----QVPKNVSPEC 240
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWI 283
K ++ +L +P R + +L W+
Sbjct: 241 KDLICRILVAEPENRPTLDQILKHPWM 267
Score = 126 bits (303), Expect = 2e-27
Identities = 72/250 (28%), Positives = 122/250 (48%), Gaps = 10/250 (4%)
Query: 339 AEYRNASKNDKLSILACKVIDTSTAP-RDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRR 397
A+ + + + A KV S D +K+F REI+ L H ++V+ H F
Sbjct: 27 AKVYKVEQTETKKVFAIKVFPKSNLKDNDDIKRF-QREIDTTANLKHDNIVNMHDFFSDE 85
Query: 398 YKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVL 457
+++ + Y + G+L++++ + + E A + Q+ A+ Y H +AHRD K ENVL
Sbjct: 86 NNFYLVLDYCQNGELMDYIAKNKRIAEPTAALIFEQIVAAVAYCHSFGVAHRDFKPENVL 145
Query: 458 LTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGI 517
+VK+SDFG K+ TFCGS Y+APE L Y + +D+WSLG+
Sbjct: 146 FERFPHVKVSDFGLCGYMETSKM----MTTFCGSPCYSAPECLYHKAYDGQKSDIWSLGV 201
Query: 518 VVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLK 577
+Y+M+ P+ +I + + + N++ +S CK LI +L +NR
Sbjct: 202 NLYLMVTGKHPWNISNINVMMRDIVTCNYQVPK----NVSPECKDLICRILVAEPENRPT 257
Query: 578 IYDIVNSEWI 587
+ I+ W+
Sbjct: 258 LDQILKHPWM 267
>UniRef50_A2DHM8 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 494
Score = 150 bits (364), Expect = 1e-34
Identities = 82/234 (35%), Positives = 132/234 (56%), Gaps = 11/234 (4%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIE-TAKAPKDFVVKFL 68
E T + K Y + + +G G AKV L E + + +A KII+ +A K + + +
Sbjct: 2 ESQTKIGK-YNVIRTLGSGTTAKVKLAE----DTTDGKLVAIKIIKKSAFEVKPDLQRKI 56
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTR 128
RE+ ++ L+HPHL+ + + + YI + Y E+G+L Y++ G S A R
Sbjct: 57 RREVALMRLLDHPHLLKLIEVLESPHHMYIVLEYAEHGELFDYLVSRGRFSPEVAMKMFR 116
Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
Q+ G+ YLH+ I HRD+K EN+LL + ++K++DFGF+R+ + ++ET CGS
Sbjct: 117 QIIYGIDYLHQHMICHRDLKPENILLDKSDHIKIADFGFARWMPDK-----IAETSCGSP 171
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKY 242
YAAPE++RG Y + D+WS GV+L+ +L +PFDD +R L + Y
Sbjct: 172 HYAAPEVIRGLAYDGRKADIWSCGVILYALLAGRLPFDDPSIRNLLSKVKSGHY 225
Score = 136 bits (328), Expect = 2e-30
Identities = 64/187 (34%), Positives = 110/187 (58%), Gaps = 6/187 (3%)
Query: 352 ILACKVIDTSTAP-RDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERG 410
++A K+I S + +++ + RE+ ++ L HPHL+ + + + +I + Y E G
Sbjct: 35 LVAIKIIKKSAFEVKPDLQRKIRREVALMRLLDHPHLLKLIEVLESPHHMYIVLEYAEHG 94
Query: 411 DLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFG 470
+L ++++ RG + A RQ+ I Y+H+ I HRD+K EN+LL + ++K++DFG
Sbjct: 95 ELFDYLVSRGRFSPEVAMKMFRQIIYGIDYLHQHMICHRDLKPENILLDKSDHIKIADFG 154
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
FAR DK +ET CGS Y APE+++G Y + D+WS G+++Y +L +PF+
Sbjct: 155 FARWMPDK-----IAETSCGSPHYAAPEVIRGLAYDGRKADIWSCGVILYALLAGRLPFD 209
Query: 531 DKHIKQL 537
D I+ L
Sbjct: 210 DPSIRNL 216
>UniRef50_A5DU66 Cluster: Putative uncharacterized protein; n=2;
Eukaryota|Rep: Putative uncharacterized protein -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 1388
Score = 150 bits (364), Expect = 1e-34
Identities = 77/211 (36%), Positives = 122/211 (57%), Gaps = 7/211 (3%)
Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127
+ REI ++ LNHP+++ ++ +++ Y+ + Y E G+L +++ G + E +A +
Sbjct: 98 IEREIIIMKLLNHPNVLRLYDVWETSKALYLVLEYVEGGELFDLLVERGALQEAEAIKYF 157
Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187
RQ+ LG Y H L I HRD+K EN+LL A NVKL+DFG + +ES+++ L ET CGS
Sbjct: 158 RQIILGTAYCHALGICHRDLKPENLLLNAQLNVKLADFGMA--ALESNDK--LLETSCGS 213
Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSR 247
YAAPEI+ G Y +D+WS GV+LF +L +PFDD +R L + +
Sbjct: 214 PHYAAPEIVSGLKYHGAASDVWSCGVILFALLTGRLPFDDENIRNLLLKVQAGNFEM--- 270
Query: 248 VASILSLECKTVVKHLLEPDPGLRHSATNVL 278
+S + + ++ +LE DP R S +L
Sbjct: 271 PLDEISYDAQDLIAKMLEVDPTRRISTDKIL 301
Score = 142 bits (345), Expect = 2e-32
Identities = 86/268 (32%), Positives = 149/268 (55%), Gaps = 13/268 (4%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ REI ++ L+HP+++ + +++ ++ + Y+E G+L + +++RGA+QE +A +
Sbjct: 98 IEREIIIMKLLNHPNVLRLYDVWETSKALYLVLEYVEGGELFDLLVERGALQEAEAIKYF 157
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
RQ+ L Y H L I HRD+K EN+LL A NVKL+DFG A + + KL ET CGS
Sbjct: 158 RQIILGTAYCHALGICHRDLKPENLLLNAQLNVKLADFGMAALESNDKL----LETSCGS 213
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y APEI+ G Y +DVWS G++++ +L +PF+D++I+ L N++
Sbjct: 214 PHYAAPEIVSGLKYHGAASDVWSCGVILFALLTGRLPFDDENIRNLLLKVQAGNFEMP-- 271
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRL---KI--YDIVNSEWIAMDSRLLEWT-PQETLAYK 605
+D IS + + LI MLE + R+ KI + ++ I + + E + P AYK
Sbjct: 272 -LDEISYDAQDLIAKMLEVDPTRRISTDKILKHPLLTKYPIPNEDLISEKSLPHPETAYK 330
Query: 606 KAREEKNKLHKTVETVELPGSSKTEHKV 633
KN + + + + + ++E ++
Sbjct: 331 SLGSTKNIDKQILSNLSILWADRSEQEI 358
>UniRef50_P22987 Cluster: Protein kinase kin1; n=1;
Schizosaccharomyces pombe|Rep: Protein kinase kin1 -
Schizosaccharomyces pombe (Fission yeast)
Length = 891
Score = 150 bits (364), Expect = 1e-34
Identities = 69/214 (32%), Positives = 123/214 (57%), Gaps = 8/214 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE + L HP++ ++ Y++ +++ G +L++++ G ++E QAR + RQ
Sbjct: 190 REAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQARKFVRQ 249
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+ A+ Y+H+ + HRD+K EN+L++ ++K+ DFG + + + R TFCGSL
Sbjct: 250 IGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNL----YRRQSRLRTFCGSLY 305
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
+ APE+L PY+ DVWS GIV+YV++ +PF+D+++ LH A+I K Y
Sbjct: 306 FAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALH-AKIKKG---TVEYP 361
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+S +CK L+ ML + R + +++N W+
Sbjct: 362 SYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWM 395
Score = 149 bits (361), Expect = 2e-34
Identities = 74/238 (31%), Positives = 128/238 (53%), Gaps = 9/238 (3%)
Query: 46 KSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTEN 105
K+ + + + A++ K+ ++ + RE + L HP++ ++ + YY+ + +
Sbjct: 167 KAAASAEATKAAQSEKNKEIRTV-REAALSTLLRHPYICEARDVYITNSHYYMVFEFVDG 225
Query: 106 GDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDF 165
G +L YI+ +G + E QAR + RQ+ L YLH+ + HRD+K EN+L++ ++K+ DF
Sbjct: 226 GQMLDYIISHGKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDF 285
Query: 166 GFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF 225
G S T+CGS+ +AAPE+L +PY D+WS G+VL+V++ +PF
Sbjct: 286 GLSNLYRRQSR----LRTFCGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPF 341
Query: 226 DDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
DD M L+ K + S LS +CK ++ +L DP R + VL+ W+
Sbjct: 342 DDQNMSALH----AKIKKGTVEYPSYLSSDCKGLLSRMLVTDPLKRATLEEVLNHPWM 395
>UniRef50_UPI00015B5491 Cluster: PREDICTED: similar to br
serine/threonine-protein kinase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to br
serine/threonine-protein kinase - Nasonia vitripennis
Length = 802
Score = 150 bits (363), Expect = 1e-34
Identities = 83/267 (31%), Positives = 146/267 (54%), Gaps = 17/267 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G+G V L + S K +A KII K + ++K + REI ++ +
Sbjct: 33 YRLEKTLGKGQTGLVKLGVHCV---SGKK-VAVKIINREKLSESVLIK-VEREIAIMKLI 87
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HPH++ + +++ K Y+ + + G+L Y++K G ++ +AR + RQ+ L + H
Sbjct: 88 DHPHVLGLSDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARRFFRQIISALDFCH 147
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPV--LSETYCGSMSYAAPEIL 196
I HRD+K EN+LL N+K++DFG + QP + ET CGS YA PE++
Sbjct: 148 SHSICHRDLKPENLLLDEKNNIKIADFGMASL------QPAGSMLETSCGSPHYACPEVI 201
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
RG+ Y + D+WS GV+L+ +L ++PFDD +R+L E K R + + +C
Sbjct: 202 RGEKYDGRRADVWSCGVILYALLVGALPFDDDNLRQLLE----KVKRGVFHIPHFVPPDC 257
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ +++ ++E +P R + + W+
Sbjct: 258 QNLLRSMIEVNPDKRLTLAEINRHVWV 284
Score = 135 bits (326), Expect = 4e-30
Identities = 68/235 (28%), Positives = 130/235 (55%), Gaps = 9/235 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I+ + K + REI ++ + HPH++ +++ + ++ + ++ G+L
Sbjct: 59 VAVKIINREKLSESVLIK-VEREIAIMKLIDHPHVLGLSDVYENKKYLYLVLEHVSGGEL 117
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++++G + +AR + RQ+ A+ + H I HRD+K EN+LL N+K++DFG A
Sbjct: 118 FDYLVKKGRLTPKEARRFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIKIADFGMA 177
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ + ET CGS Y PE+++G Y + DVWS G+++Y +L A+PF+D
Sbjct: 178 SLQPAGSM----LETSCGSPHYACPEVIRGEKYDGRRADVWSCGVILYALLVGALPFDDD 233
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+++QL + K F + + +C+ L+ M+E N RL + +I W+
Sbjct: 234 NLRQLLEKV--KRGVFHIPHF--VPPDCQNLLRSMIEVNPDKRLTLAEINRHVWV 284
>UniRef50_A2FK34 Cluster: CAMK family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 498
Score = 150 bits (363), Expect = 1e-34
Identities = 85/240 (35%), Positives = 136/240 (56%), Gaps = 10/240 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKF-LPREIDVLVR 77
Y L + +G+G ++KV L E+ +++H+ A KII+ +K ++ + + REI ++
Sbjct: 10 YILLQIIGQGNFSKVKLAEH---KETHQR-YAVKIIKKSKLEENPELSSKIQREIALMKI 65
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
L+H H+I + I + +I Y ENG+L Y++ +S ++ RQ+ GL YL
Sbjct: 66 LDHTHIIKLIEIAESPRHLFIIQEYAENGELFDYLVARRYLSVEESMRIFRQIIYGLDYL 125
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H I HRD+K EN+LL ++ NVK++DFGF+R+ S Q T CGS YAAPE++R
Sbjct: 126 HSRGICHRDLKPENLLLDSHNNVKIADFGFARWLKYSTTQ-----TSCGSPHYAAPEVIR 180
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
G PY + D+WS GV+L+ +L +PF++ + L + +YR A I L K
Sbjct: 181 GIPYNGQKADIWSCGVILYALLAGRLPFNEPNFKDLVSKIKNGQYRMPDFPAVIKDLVAK 240
Score = 127 bits (307), Expect = 8e-28
Identities = 75/247 (30%), Positives = 131/247 (53%), Gaps = 14/247 (5%)
Query: 335 RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIF 394
+V LAE++ + + I+ ++ + + + REI ++ L H H++ I
Sbjct: 23 KVKLAEHKETHQRYAVKIIKKSKLEENPE----LSSKIQREIALMKILDHTHIIKLIEIA 78
Query: 395 QRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCE 454
+ FI Y E G+L ++++ R + +++ RQ+ + Y+H I HRD+K E
Sbjct: 79 ESPRHLFIIQEYAENGELFDYLVARRYLSVEESMRIFRQIIYGLDYLHSRGICHRDLKPE 138
Query: 455 NVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWS 514
N+LL ++ NVK++DFGFAR L ++T CGS Y APE+++G PY + D+WS
Sbjct: 139 NLLLDSHNNVKIADFGFARW-----LKYSTTQTSCGSPHYAAPEVIRGIPYNGQKADIWS 193
Query: 515 LGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQN 574
G+++Y +L +PF + + K L ++I KN ++R + K L+ ML N +
Sbjct: 194 CGVILYALLAGRLPFNEPNFKDL-VSKI-KNGQYRMPDFPAV---IKDLVAKMLCVNPEC 248
Query: 575 RLKIYDI 581
R+ I I
Sbjct: 249 RITIEQI 255
>UniRef50_A0E8Y3 Cluster: Chromosome undetermined scaffold_83, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_83,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 666
Score = 150 bits (363), Expect = 1e-34
Identities = 86/271 (31%), Positives = 144/271 (53%), Gaps = 12/271 (4%)
Query: 12 NTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPRE 71
N + Y+L K +GEG + KV L + ++ +A KI+E + + V+ + RE
Sbjct: 62 NRRIIGNYQLIKTLGEGTFGKVKLAVHLKSQEK----VAIKILEKERIVEVADVERVSRE 117
Query: 72 IDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLA 131
I +L + H H+I ++ I + +I M + G+L YI+K+ + E +A + +QL
Sbjct: 118 IHILKLIRHKHVIQLYEIIETPKHIFIVMEFANGGELFEYIVKHQRLQEIEACKFYQQLI 177
Query: 132 LGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYA 191
G++YLH+L I HRD+K EN+LL N ++K+ DFG + + L +T CGS YA
Sbjct: 178 SGIEYLHKLCIVHRDLKPENLLLDFNNSIKIVDFGLGNTYKKGE----LLKTACGSPCYA 233
Query: 192 APEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASI 251
APE++ G+ Y D+WS GV+LF + +PF+D LY++ + +Y ++
Sbjct: 234 APEMIAGQKYDCLMVDIWSSGVILFASICGYLPFEDQNTSALYKKILNGEY----QIPKF 289
Query: 252 LSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
+S E +K +L DP R + + W
Sbjct: 290 VSNEGANFIKAVLTTDPKKRITVEQMKAHPW 320
Score = 116 bits (280), Expect = 2e-24
Identities = 65/233 (27%), Positives = 120/233 (51%), Gaps = 8/233 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
REI +L + H H++ + I + FI M + G+L E++++ +QE +A + +Q
Sbjct: 116 REIHILKLIRHKHVIQLYEIIETPKHIFIVMEFANGGELFEYIVKHQRLQEIEACKFYQQ 175
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
L I+Y+H+L I HRD+K EN+LL N ++K+ DFG K E+ +T CGS
Sbjct: 176 LISGIEYLHKLCIVHRDLKPENLLLDFNNSIKIVDFGLGN---TYKKGEL-LKTACGSPC 231
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y APE++ G Y D+WS G++++ + +PFED++ L++ +N ++
Sbjct: 232 YAAPEMIAGQKYDCLMVDIWSSGVILFASICGYLPFEDQNTSALYKKILNGEYQIPK--- 288
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLLEWTPQETLAYKK 606
+S+ I +L + + R+ + + W + + +P + Y +
Sbjct: 289 -FVSNEGANFIKAVLTTDPKKRITVEQMKAHPWFNLYQSQSKISPGIIVGYNR 340
>UniRef50_A0E675 Cluster: Chromosome undetermined scaffold_8, whole
genome shotgun sequence; n=5; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_8,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 627
Score = 150 bits (363), Expect = 1e-34
Identities = 87/274 (31%), Positives = 144/274 (52%), Gaps = 12/274 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G G + V L + + +A KI+E + + V+ + REI +L +
Sbjct: 28 YQLVKTLGVGTFGLVKLGLHQITGEK----VAIKILEKERIIEVADVERVSREIHILKLI 83
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
H H+I ++ I + K ++ M + +NG+L YI+KN + E +A ++L G++Y+H
Sbjct: 84 RHRHVIQLYEIIETKKHIFLVMEFCDNGELFDYIVKNEKLDEIEACRIFQELISGIEYIH 143
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+L I HRD+K EN+LL +K+ DFG S + Q L +T CGS YAAPE++ G
Sbjct: 144 KLNIVHRDLKPENLLLDHQNQIKIVDFGLS----NTYKQGELLKTACGSPCYAAPEMIAG 199
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y D+WS GV+LF + +PF+D LY++ +G +Y V S + +
Sbjct: 200 HRYQSILVDIWSCGVILFATICGQLPFEDKHTSDLYKKILGGQYTIPPHV----SQDGQQ 255
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTL 292
+K LL DP R + + W + R+ ++
Sbjct: 256 FLKGLLNTDPAKRFNLEQIKQHPWFRLYKRVQSI 289
Score = 116 bits (279), Expect = 2e-24
Identities = 71/274 (25%), Positives = 130/274 (47%), Gaps = 13/274 (4%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
REI +L + H H++ + I + + F+ M + + G+L +++++ + E +A ++
Sbjct: 75 REIHILKLIRHRHVIQLYEIIETKKHIFLVMEFCDNGELFDYIVKNEKLDEIEACRIFQE 134
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
L I+Y+H+L I HRD+K EN+LL +K+ DFG + +L +T CGS
Sbjct: 135 LISGIEYIHKLNIVHRDLKPENLLLDHQNQIKIVDFGLSNTYKQGEL----LKTACGSPC 190
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y APE++ G Y D+WS G++++ + +PFEDKH L++ + +
Sbjct: 191 YAAPEMIAGHRYQSILVDIWSCGVILFATICGQLPFEDKHTSDLYKKILGGQYTIPPH-- 248
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLLEWTPQETLAYKKAREEKNK 613
+S + ++ + +L + R + I W + R+ + Y + +
Sbjct: 249 --VSQDGQQFLKGLLNTDPAKRFNLEQIKQHPWFRLYKRVQSIPQGIIIGYSRIPID--- 303
Query: 614 LHKTVETVELPGSSKTEHKVCLPDSLVENNLDGA 647
V+ + G S K CL D+ NNL A
Sbjct: 304 -DVIVDQLATKGFSSDYIKKCL-DANKHNNLTTA 335
>UniRef50_A0DFC5 Cluster: Chromosome undetermined scaffold_49, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_49,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 567
Score = 150 bits (363), Expect = 1e-34
Identities = 96/268 (35%), Positives = 145/268 (54%), Gaps = 19/268 (7%)
Query: 11 ENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR 70
E T + Y L + +G+G + KV L Y + D + +A KI+E K D + R
Sbjct: 5 EQTKQVQNYVLDRTLGKGTFGKVKLG-YHTICDEY---VAVKILEKRKIETDADFIRVQR 60
Query: 71 EIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGC-------VSENQA 123
EI +L ++ HP++I ++ I + T Y+ M Y + G+L YI+K +SE A
Sbjct: 61 EITILRKVEHPNVIKLYEILESDTNLYLVMEYAKGGELFDYIVKKNQQIKKLIRLSELAA 120
Query: 124 RVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSET 183
+ QL ++YLH +I HRD+K EN+LL N+K++DFG S E+D +T
Sbjct: 121 TKFFIQLIDAVEYLHSQKIVHRDLKPENLLLDEQRNLKVADFGLSNIYKETDQV----KT 176
Query: 184 YCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYR 243
CGS YAAPE+L GK Y + +D+WS G++L+ ML +PF+ +KLYE KY
Sbjct: 177 ACGSPCYAAPEMLYGKLYGGQKSDIWSCGIILYAMLCGYLPFEHENTKKLYEM---IKYE 233
Query: 244 FRSRVASILSLECKTVVKHLLEPDPGLR 271
+ +I S + ++K LL DP LR
Sbjct: 234 DYDKPKNI-SPAAQDLLKQLLIKDPSLR 260
Score = 117 bits (281), Expect = 1e-24
Identities = 64/197 (32%), Positives = 118/197 (59%), Gaps = 16/197 (8%)
Query: 350 LSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMER 409
+ IL + I+T DF++ + REI +L K+ HP+++ + I + ++ M Y +
Sbjct: 41 VKILEKRKIETDA---DFIR--VQREITILRKVEHPNVIKLYEILESDTNLYLVMEYAKG 95
Query: 410 GDLLEFVLQRGA-------VQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQ 462
G+L ++++++ + E A + QL A++Y+H +I HRD+K EN+LL +
Sbjct: 96 GELFDYIVKKNQQIKKLIRLSELAATKFFIQLIDAVEYLHSQKIVHRDLKPENLLLDEQR 155
Query: 463 NVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVM 522
N+K++DFG + + K+ ++++ T CGS Y APE+L G Y + +D+WS GI++Y M
Sbjct: 156 NLKVADFGLSN--IYKETDQVK--TACGSPCYAAPEMLYGKLYGGQKSDIWSCGIILYAM 211
Query: 523 LNRAMPFEDKHIKQLHQ 539
L +PFE ++ K+L++
Sbjct: 212 LCGYLPFEHENTKKLYE 228
>UniRef50_Q75DQ1 Cluster: ABL034Wp; n=1; Eremothecium gossypii|Rep:
ABL034Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 1425
Score = 150 bits (363), Expect = 1e-34
Identities = 94/302 (31%), Positives = 159/302 (52%), Gaps = 21/302 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFV-VKFLP----REID 73
+KL K +G+G+ +V L +K A KI+ + V LP REI
Sbjct: 61 WKLGKTLGKGSSGRVRL----AKNMQSGKLAAIKIVPKRNVRHNQKQVTALPYGIEREII 116
Query: 74 VLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALG 133
++ + HP+++ ++ +++ K++ Y+ + Y E G+L Y++ G + E +A + +Q+ G
Sbjct: 117 IMKLITHPNIMALYEVWENKSELYLVLEYVEGGELFDYLIARGKLPEQEAIHYFKQIVQG 176
Query: 134 LQYLHELEIAHRDIKCENVLL-TANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAA 192
+ Y H I HRD+K EN+LL N VK++DFG + +E+ N+ L ET CGS YA+
Sbjct: 177 VSYCHNFNICHRDLKPENLLLDKKNKTVKIADFGMA--ALETTNR--LLETSCGSPHYAS 232
Query: 193 PEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASIL 252
PEI+ G+ Y P+D+WS G++LF +L +PF+D +RKL + +Y+ S V
Sbjct: 233 PEIVMGQKYHGSPSDVWSCGIILFALLTGHLPFNDDNVRKLLLKVQHGRYQMPSNV---- 288
Query: 253 SLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKEDRRKLSD 312
S E K ++ +L DP R + +L+ + + A E+R K+ D
Sbjct: 289 SKEAKDLISKILVVDPEKRITVDKILEHPLLV---KYDNPGKGGLACPLEKPEERPKVLD 345
Query: 313 VH 314
+H
Sbjct: 346 IH 347
Score = 130 bits (314), Expect = 1e-28
Identities = 72/252 (28%), Positives = 138/252 (54%), Gaps = 9/252 (3%)
Query: 332 SAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTH 391
S+ RV LA+ + K + I+ + + + + + REI ++ ++HP+++ +
Sbjct: 71 SSGRVRLAKNMQSGKLAAIKIVPKRNVRHNQKQVTALPYGIEREIIIMKLITHPNIMALY 130
Query: 392 SIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDI 451
+++ + + ++ + Y+E G+L ++++ RG + E +A + +Q+ + Y H I HRD+
Sbjct: 131 EVWENKSELYLVLEYVEGGELFDYLIARGKLPEQEAIHYFKQIVQGVSYCHNFNICHRDL 190
Query: 452 KCENVLL-TANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPT 510
K EN+LL N+ VK++DFG A + +L ET CGS Y +PEI+ G Y P+
Sbjct: 191 KPENLLLDKKNKTVKIADFGMAALETTNRL----LETSCGSPHYASPEIVMGQKYHGSPS 246
Query: 511 DVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEP 570
DVWS GI+++ +L +PF D ++++L + K R + +S K LI +L
Sbjct: 247 DVWSCGIILFALLTGHLPFNDDNVRKL----LLKVQHGRYQMPSNVSKEAKDLISKILVV 302
Query: 571 NHQNRLKIYDIV 582
+ + R+ + I+
Sbjct: 303 DPEKRITVDKIL 314
>UniRef50_UPI0000F20BD0 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 479
Score = 149 bits (362), Expect = 2e-34
Identities = 84/266 (31%), Positives = 149/266 (56%), Gaps = 14/266 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
YK+ +G G ++KV L ++ +D +A KI++ + + L REI + L
Sbjct: 69 YKVRGQIGCGNFSKVKLATHALTKDK----VAVKIMDKMRLDVQ-TQRMLTREISNMESL 123
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP+L+ + + + ++ Y+ + + GDL + I G +++ ++++ Q+ ++Y+H
Sbjct: 124 YHPNLLQLFEVLETPSRLYLILEFAGGGDLHTRISSGGKLTDLESKIVFAQILSAVKYMH 183
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
E I HRD+K ENVL T N +K++DFGFS V + NQ + +T+CGS YAAPE+ +
Sbjct: 184 ENNIIHRDLKAENVLYTTNGCIKVADFGFST-KVNNRNQAL--DTFCGSPPYAAPELFKD 240
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASI-LSLECK 257
Y P D+W++GV+LF M+ S+PF + KL + + Y V I +S C+
Sbjct: 241 DSYIGPPVDVWAMGVLLFFMVTGSLPFRADTVPKLRQSVLEGAY-----VLPIWVSAPCQ 295
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWI 283
+++ +L+P+P R + +L EW+
Sbjct: 296 RLIRGILKPEPSERCALDQMLGCEWL 321
Score = 130 bits (313), Expect = 2e-28
Identities = 66/219 (30%), Positives = 121/219 (55%), Gaps = 7/219 (3%)
Query: 369 KKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQAR 428
++ L REI + L HP+L+ + + + ++ + + GDL + G + + +++
Sbjct: 110 QRMLTREISNMESLYHPNLLQLFEVLETPSRLYLILEFAGGGDLHTRISSGGKLTDLESK 169
Query: 429 IWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETF 488
I Q+ A++YMHE I HRD+K ENVL T N +K++DFGF+ V+ + + +TF
Sbjct: 170 IVFAQILSAVKYMHENNIIHRDLKAENVLYTTNGCIKVADFGFSTK-VNNRNQAL--DTF 226
Query: 489 CGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKF 548
CGS Y APE+ + Y+ P DVW++G++++ M+ ++PF + +L Q+ + +
Sbjct: 227 CGSPPYAAPELFKDDSYIGPPVDVWAMGVLLFFMVTGSLPFRADTVPKLRQSVLEGAYVL 286
Query: 549 RSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+S C+RLI +L+P R + ++ EW+
Sbjct: 287 PI----WVSAPCQRLIRGILKPEPSERCALDQMLGCEWL 321
>UniRef50_Q4RVL2 Cluster: Chromosome 15 SCAF14992, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 15
SCAF14992, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 827
Score = 149 bits (362), Expect = 2e-34
Identities = 79/264 (29%), Positives = 141/264 (53%), Gaps = 13/264 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G+G V L + +A KI+ K + ++K + REI +L +
Sbjct: 17 YRLEKTLGKGQTGLVKLGVHCITGQK----VAIKIVNREKLSESVLMK-VEREIAILKLI 71
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH++ +H +++ Y+ + + G+L Y++K G ++ +AR + RQ+ L + H
Sbjct: 72 EHPHVLKLHDVYENNKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCH 131
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K EN+LL N++++DFG + V L ET CGS YA PE++RG
Sbjct: 132 SHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDS----LLETSCGSPHYACPEVIRG 187
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y + D+WS GV+LF +L ++PFD +R+L E+ + + + +C++
Sbjct: 188 EKYDGRRADVWSCGVILFALLVGALPFDHDNLRQLLEKVKSGVF----HMPHFIPPDCQS 243
Query: 259 VVKHLLEPDPGLRHSATNVLDSEW 282
++K ++E +P R + + W
Sbjct: 244 LLKGMIEVNPEKRLTLEAIQKHAW 267
Score = 136 bits (330), Expect = 1e-30
Identities = 69/234 (29%), Positives = 130/234 (55%), Gaps = 9/234 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ + K + REI +L + HPH++ H +++ ++ + ++ G+L
Sbjct: 43 VAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENNKYLYLVLEHVSGGEL 101
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++++G + +AR + RQ+ A+ + H I HRD+K EN+LL N++++DFG A
Sbjct: 102 FDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA 161
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ V L ET CGS Y PE+++G Y + DVWS G++++ +L A+PF+
Sbjct: 162 SLQVGDSL----LETSCGSPHYACPEVIRGEKYDGRRADVWSCGVILFALLVGALPFDHD 217
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+++QL + K+ F + I +C+ L+ M+E N + RL + I W
Sbjct: 218 NLRQLLEKV--KSGVFHMPHF--IPPDCQSLLKGMIEVNPEKRLTLEAIQKHAW 267
>UniRef50_Q240T9 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1401
Score = 149 bits (362), Expect = 2e-34
Identities = 84/265 (31%), Positives = 142/265 (53%), Gaps = 14/265 (5%)
Query: 23 KFVGEGAYAKVYLTEYSSKEDS------HKSTL-ACKIIETAKAPKDFVVKFLPREIDVL 75
K +G G + KV L ++ + + ST KI+E D + + EI +L
Sbjct: 92 KTIGRGTFGKVKLGVHTLTNEKVNIFSVNLSTAQTIKILEKRMIQGDQDMLSVQSEISIL 151
Query: 76 VRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQ 135
+NHP++ ++ I + Y+ + Y +NG+L +I++ ++E + + Q+ L+
Sbjct: 152 KSVNHPNISQLYQIIETNDCLYLVLEYAQNGELFDFIVRKRRLTEQETCLVFAQILNALE 211
Query: 136 YLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEI 195
YLH+L I+HRD+K EN+L + +KL DFG S+ C E+D Q T CGS YA+PE
Sbjct: 212 YLHDLGISHRDLKPENLLFDYKYELKLVDFGLSKICQEADQQ---LYTCCGSPCYASPET 268
Query: 196 LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLE 255
+ +PY + DLWS G++LF ML +PFDD L+ + + +Y + + +S E
Sbjct: 269 ISSQPYVGRYVDLWSCGIILFAMLCGYLPFDDDNQASLFAKIISCEY----YIPTDISPE 324
Query: 256 CKTVVKHLLEPDPGLRHSATNVLDS 280
+++ LL+ DP R S ++ +S
Sbjct: 325 ASYLIRGLLKKDPNQRLSIKDIKNS 349
Score = 122 bits (294), Expect = 3e-26
Identities = 66/211 (31%), Positives = 117/211 (55%), Gaps = 9/211 (4%)
Query: 375 EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQL 434
EI +L ++HP++ + I + ++ + Y + G+L +F++++ + E + + Q+
Sbjct: 147 EISILKSVNHPNISQLYQIIETNDCLYLVLEYAQNGELFDFIVRKRRLTEQETCLVFAQI 206
Query: 435 ALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSY 494
A++Y+H+L I+HRD+K EN+L +KL DFG +++C + + + T CGS Y
Sbjct: 207 LNALEYLHDLGISHRDLKPENLLFDYKYELKLVDFGLSKICQEA---DQQLYTCCGSPCY 263
Query: 495 TAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYID 554
+PE + PY+ + D+WS GI+++ ML +PF+D + L I+ + YI
Sbjct: 264 ASPETISSQPYVGRYVDLWSCGIILFAMLCGYLPFDDDNQASLFAKIISCEY-----YIP 318
Query: 555 T-ISDNCKRLIGLMLEPNHQNRLKIYDIVNS 584
T IS LI +L+ + RL I DI NS
Sbjct: 319 TDISPEASYLIRGLLKKDPNQRLSIKDIKNS 349
>UniRef50_Q19962 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 333
Score = 149 bits (362), Expect = 2e-34
Identities = 94/272 (34%), Positives = 142/272 (52%), Gaps = 17/272 (6%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
+ K Y++ +G+G ++ V+LT KED K L ++ + A K F F+ E+++
Sbjct: 67 IEKQYEIGAIIGKGNFSSVHLTR--RKEDGTKCALK-QVEKRAMRGKCF---FVDNEVEM 120
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
L + H H+I + F + +Y+I + + GDL I KNG + E A + T Q+A L
Sbjct: 121 LSLIQHDHIISIIDAFSTENQYFIVFEHAQYGDLYETIRKNGRIEEPDAAIITLQVASAL 180
Query: 135 QYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETY--CGSMSYAA 192
YLHE + HRD+K EN+LL F+VKL DFG + C +L Y CG+ +Y A
Sbjct: 181 NYLHERNVVHRDVKPENLLLVDKFSVKLCDFGLA--C------HILGPLYRICGTPTYCA 232
Query: 193 PEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASIL 252
PE+LR Y + D+WSLGVVL+VML PF +L++ M K +
Sbjct: 233 PEVLRETGYSTR-CDIWSLGVVLYVMLVGYAPFRAPDQTRLFKLIMQAKPNLDMPEWKGI 291
Query: 253 SLECKTVVKHLLEPDPGLRHSATNVLDSEWIA 284
SL+ K +V L+ R A+ ++ WIA
Sbjct: 292 SLKAKDLVSRLMNKTEERRPLASQIMAHPWIA 323
Score = 124 bits (298), Expect = 1e-26
Identities = 72/218 (33%), Positives = 108/218 (49%), Gaps = 7/218 (3%)
Query: 371 FLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIW 430
F+ E+EML + H H++ F +YFI + + GDL E + + G ++E A I
Sbjct: 113 FVDNEVEMLSLIQHDHIISIIDAFSTENQYFIVFEHAQYGDLYETIRKNGRIEEPDAAII 172
Query: 431 TRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCG 490
T Q+A A+ Y+HE + HRD+K EN+LL +VKL DFG A + CG
Sbjct: 173 TLQVASALNYLHERNVVHRDVKPENLLLVDKFSVKLCDFGLACHILGPLYR------ICG 226
Query: 491 SLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRS 550
+ +Y APE+L+ T Y + D+WSLG+V+YVML PF +L + +
Sbjct: 227 TPTYCAPEVLRETGYSTR-CDIWSLGVVLYVMLVGYAPFRAPDQTRLFKLIMQAKPNLDM 285
Query: 551 RYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
IS K L+ ++ + R I+ WIA
Sbjct: 286 PEWKGISLKAKDLVSRLMNKTEERRPLASQIMAHPWIA 323
>UniRef50_Q6M929 Cluster: Related to serine/threonine-specific
protein kinase KIN1; n=3; Sordariaceae|Rep: Related to
serine/threonine-specific protein kinase KIN1 -
Neurospora crassa
Length = 880
Score = 149 bits (362), Expect = 2e-34
Identities = 76/215 (35%), Positives = 121/215 (56%), Gaps = 8/215 (3%)
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
RE ++ LNH ++ + + + +Y+ Y G +L YI+ +G + E QAR + RQ
Sbjct: 221 REAAIVSLLNHQYICGLRDNLRTRWHWYMLFEYVNGGQMLDYIISHGKLKEKQARKFARQ 280
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSR-FCVESDNQPVLSETYCGSM 188
+A + Y H I HRD+K EN+L++ ++K+ DFG S F E D + +TYCGS+
Sbjct: 281 IASAVDYCHRNSIVHRDLKIENILISKTGDIKIIDFGLSNLFSPEEDRK---LKTYCGSL 337
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
+AAPE+L+ +PY D+WS GVVLFV++ +PFDD M L++ K +
Sbjct: 338 YFAAPELLQARPYTGPEVDVWSFGVVLFVLVCGKVPFDDQYMPALHQ----KIKKGAVDY 393
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ LS ECK ++ +L DP R + V++ W+
Sbjct: 394 PNWLSSECKHLISRMLVTDPKQRATMQEVMNHPWM 428
Score = 149 bits (362), Expect = 2e-34
Identities = 69/214 (32%), Positives = 126/214 (58%), Gaps = 6/214 (2%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE ++ L+H ++ + R+ +++ Y+ G +L++++ G ++E QAR + RQ
Sbjct: 221 REAAIVSLLNHQYICGLRDNLRTRWHWYMLFEYVNGGQMLDYIISHGKLKEKQARKFARQ 280
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+A A+ Y H I HRD+K EN+L++ ++K+ DFG + + ++ +++ T+CGSL
Sbjct: 281 IASAVDYCHRNSIVHRDLKIENILISKTGDIKIIDFGLSNLFSPEEDRKLK--TYCGSLY 338
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
+ APE+LQ PY DVWS G+V++V++ +PF+D+++ LHQ K K Y
Sbjct: 339 FAAPELLQARPYTGPEVDVWSFGVVLFVLVCGKVPFDDQYMPALHQ----KIKKGAVDYP 394
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ +S CK LI ML + + R + +++N W+
Sbjct: 395 NWLSSECKHLISRMLVTDPKQRATMQEVMNHPWM 428
>UniRef50_Q2KFW9 Cluster: Putative uncharacterized protein; n=2;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea 70-15
Length = 1208
Score = 149 bits (362), Expect = 2e-34
Identities = 76/206 (36%), Positives = 119/206 (57%), Gaps = 7/206 (3%)
Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127
L RE+ +L + HP+++ ++ I++ + Y+ + Y E GDL +I K+G + E +A
Sbjct: 181 LEREVAILKLIEHPNIVKLYDIWENSNEIYLILEYVERGDLFDFISKHGPMPEEEAIFVF 240
Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187
RQ+ L+Y H I HRD+K EN+LL +N VK++DFG + + P+ T+CGS
Sbjct: 241 RQIMSALEYCHSYGICHRDLKPENILLKSNGQVKIADFGMAAL-HQGPRTPLW--TFCGS 297
Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSR 247
YAAPE+LR K Y + +D+WS+GV+LF M+ +PFDD M ++ + Y
Sbjct: 298 PHYAAPELLREKAYRGEKSDIWSMGVILFAMMAARLPFDDEDMNLMFAKARKAIY----H 353
Query: 248 VASILSLECKTVVKHLLEPDPGLRHS 273
+ S S E K ++ LL+ DP R S
Sbjct: 354 MPSFFSDEAKDLIHRLLQVDPRKRLS 379
Score = 134 bits (325), Expect = 5e-30
Identities = 67/207 (32%), Positives = 119/207 (57%), Gaps = 7/207 (3%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
L RE+ +L + HP++V + I++ + ++ + Y+ERGDL +F+ + G + E++A
Sbjct: 181 LEREVAILKLIEHPNIVKLYDIWENSNEIYLILEYVERGDLFDFISKHGPMPEEEAIFVF 240
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
RQ+ A++Y H I HRD+K EN+LL +N VK++DFG A + + TFCGS
Sbjct: 241 RQIMSALEYCHSYGICHRDLKPENILLKSNGQVKIADFGMAALHQGPR---TPLWTFCGS 297
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y APE+L+ Y + +D+WS+G++++ M+ +PF+D+ + + + S
Sbjct: 298 PHYAAPELLREKAYRGEKSDIWSMGVILFAMMAARLPFDDEDMNLMFAKARKAIYHMPSF 357
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKI 578
+ SD K LI +L+ + + RL +
Sbjct: 358 F----SDEAKDLIHRLLQVDPRKRLSM 380
>UniRef50_Q9BYT3 Cluster: Serine/threonine-protein kinase 33; n=26;
Eumetazoa|Rep: Serine/threonine-protein kinase 33 - Homo
sapiens (Human)
Length = 514
Score = 149 bits (362), Expect = 2e-34
Identities = 89/283 (31%), Positives = 153/283 (54%), Gaps = 17/283 (6%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP 69
E + + Y + +G+G++ V E + KE K A K + KA VK L
Sbjct: 107 ENGAAIEEIYTFGRILGKGSFGIVI--EATDKETETK--WAIKKVNKEKAGSS-AVKLLE 161
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
RE+++L + H H+IH+ +F+ K Y+ M E+G+L + + G SEN+ R +
Sbjct: 162 REVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQS 221
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTA---------NFNVKLSDFGFSRFCVESDNQPVL 180
LA + YLH +I HRD+K EN+++ + N N+K++DFG + +S ++ +L
Sbjct: 222 LASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA-VKKQSRSEAML 280
Query: 181 SETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGK 240
T CG+ Y APE++ Y + D+WS+GVV++++L PF + KL+E
Sbjct: 281 QAT-CGTPIYMAPEVISAHDY-SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKG 338
Query: 241 KYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ F + V + +S K+V+K L++ DP R +A +LD++W+
Sbjct: 339 ELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWL 381
Score = 126 bits (303), Expect = 2e-27
Identities = 76/274 (27%), Positives = 139/274 (50%), Gaps = 16/274 (5%)
Query: 370 KFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARI 429
K L RE+ +L + H H++H +F+ K ++ M E G+L E + ++G E++ R
Sbjct: 158 KLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRW 217
Query: 430 WTRQLALAIQYMHELEIAHRDIKCENVLLTA---------NQNVKLSDFGFARMCVDKKL 480
+ LA AI Y+H +I HRD+K EN+++ + N N+K++DFG A +
Sbjct: 218 IIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA--VKKQSR 275
Query: 481 NEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQA 540
+E + CG+ Y APE++ Y + D+WS+G+V+Y++L PF ++L +
Sbjct: 276 SEAMLQATCGTPIYMAPEVISAHDY-SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFEL 334
Query: 541 QINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLLEWTPQE 600
F + ++ISD K ++ +++ + +R+ ++++++W+ ++L P
Sbjct: 335 IRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLT-GNKLSSVRPTN 393
Query: 601 TLAYKKAREEKNKLHKTVE-TVELPGSSKTEHKV 633
L K E KN E T E TE K+
Sbjct: 394 VLEMMK--EWKNNPESVEENTTEEKNKPSTEEKL 425
>UniRef50_UPI0000F2C213 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 762
Score = 149 bits (361), Expect = 2e-34
Identities = 91/272 (33%), Positives = 146/272 (53%), Gaps = 19/272 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKST---LACKIIETAKAPKD-FVVKFLPREIDV 74
Y + K + G++AKV E H T +A K+I+ KA +D ++ K + RE +
Sbjct: 63 YLVGKMINRGSFAKVM-------EGLHLPTGEKVAIKVIDKKKAQQDSYISKNMKREPRI 115
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
+ HPH++ ++ + + YY+ M GDLL I + E + R +TRQ+ +
Sbjct: 116 QQMVKHPHIVQLYETLETENSYYMVMELCLGGDLLDKICDQKKLDEREVRRFTRQIMSAV 175
Query: 135 QYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFC-VESDNQPVLSETYCGSMSYAAP 193
+LH I HRD+K EN LL N N+K+ DFG S +E +Q +L+ T CGS +YAAP
Sbjct: 176 GHLHHHGIVHRDLKIENFLLDENNNIKIVDFGLSNIMKLEGLSQELLN-TQCGSPAYAAP 234
Query: 194 EILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF--DDTRMRKLYEQQMGKKYRFRSRVASI 251
E+L K Y PK D+WS+GV +F ML ++PF + +++L+++ + + S V
Sbjct: 235 ELLAHKKYGPK-VDVWSIGVSMFAMLTGTLPFTVEPFNIKQLHQKMVNGEI---SSVPDN 290
Query: 252 LSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+S + LLEPDP R + + +W+
Sbjct: 291 ISSGAVHFMHSLLEPDPAKRPAIKEAMKDKWL 322
Score = 147 bits (357), Expect = 7e-34
Identities = 82/238 (34%), Positives = 128/238 (53%), Gaps = 7/238 (2%)
Query: 353 LACKVIDTSTAPRD-FVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A KVID A +D ++ K + RE + + HPH+V + + Y++ M GD
Sbjct: 89 VAIKVIDKKKAQQDSYISKNMKREPRIQQMVKHPHIVQLYETLETENSYYMVMELCLGGD 148
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
LL+ + + + E + R +TRQ+ A+ ++H I HRD+K EN LL N N+K+ DFG
Sbjct: 149 LLDKICDQKKLDEREVRRFTRQIMSAVGHLHHHGIVHRDLKIENFLLDENNNIKIVDFGL 208
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF-- 529
+ + + L++ T CGS +Y APE+L Y PK DVWS+G+ ++ ML +PF
Sbjct: 209 SNIMKLEGLSQELLNTQCGSPAYAAPELLAHKKYGPK-VDVWSIGVSMFAMLTGTLPFTV 267
Query: 530 EDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
E +IKQLHQ +N S D IS + +LEP+ R I + + +W+
Sbjct: 268 EPFNIKQLHQKMVNGE---ISSVPDNISSGAVHFMHSLLEPDPAKRPAIKEAMKDKWL 322
>UniRef50_UPI000049A5C0 Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 439
Score = 149 bits (361), Expect = 2e-34
Identities = 81/272 (29%), Positives = 152/272 (55%), Gaps = 10/272 (3%)
Query: 9 SEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68
SE+ + ++ + + +G+GA+ KVYL + +KE ++ A K+I+ + + V+
Sbjct: 111 SEDKYVSSEDFDIISLIGKGAFGKVYLVK--NKET--QTLFAMKVIQKKQVIERDEVQHS 166
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTR 128
E ++L ++ HP L++++ FQ + + Y G+L S + K ++E + + +
Sbjct: 167 LEEKNILAKIKHPFLVNLYCSFQTSVNLHYVIDYCPGGELYSLMKKEQTMNEKRTKFYAA 226
Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
QL L L++LH I +RD+K EN+L+ A+ ++L+DFG S+ + SDN + T+CG+
Sbjct: 227 QLVLALEHLHNQGIIYRDVKPENILICADGYIRLTDFGLSKMGI-SDNSK--TATFCGTP 283
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
Y APE+++ Y D W LGV+++ ML ++PF D +++LY + + F
Sbjct: 284 EYLAPEVIQNVAY-TNAIDWWGLGVLIYEMLYGTVPFYDENIQRLYHNILYNQVTFLEHT 342
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDS 280
+SLEC+ ++ LL+ +P R T+ + S
Sbjct: 343 E--ISLECRDIISQLLKKNPIERLHETDAIKS 372
Score = 124 bits (298), Expect = 1e-26
Identities = 72/235 (30%), Positives = 123/235 (52%), Gaps = 8/235 (3%)
Query: 351 SILACKVIDTSTA-PRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMER 409
++ A KVI RD V+ L E +L K+ HP LV+ + FQ + Y
Sbjct: 145 TLFAMKVIQKKQVIERDEVQHSL-EEKNILAKIKHPFLVNLYCSFQTSVNLHYVIDYCPG 203
Query: 410 GDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDF 469
G+L + + + E + + + QL LA++++H I +RD+K EN+L+ A+ ++L+DF
Sbjct: 204 GELYSLMKKEQTMNEKRTKFYAAQLVLALEHLHNQGIIYRDVKPENILICADGYIRLTDF 263
Query: 470 GFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF 529
G ++M + + ++ TFCG+ Y APE++Q Y D W LG+++Y ML +PF
Sbjct: 264 GLSKMGIS---DNSKTATFCGTPEYLAPEVIQNVAY-TNAIDWWGLGVLIYEMLYGTVPF 319
Query: 530 EDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNS 584
D++I++L+ + F IS C+ +I +L+ N RL D + S
Sbjct: 320 YDENIQRLYHNILYNQVTFLEH--TEISLECRDIISQLLKKNPIERLHETDAIKS 372
>UniRef50_UPI00015B5903 Cluster: PREDICTED: similar to Melk protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to Melk
protein - Nasonia vitripennis
Length = 1491
Score = 149 bits (360), Expect = 3e-34
Identities = 93/298 (31%), Positives = 155/298 (52%), Gaps = 19/298 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR---EIDVL 75
Y+L K VG G +AKV L + + + +A KI+E A +D LPR EI +
Sbjct: 920 YELEKTVGCGGFAKVKLATHVATGEK----VAIKIMEKAALGED-----LPRVGLEISAM 970
Query: 76 VRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQ 135
L H H+ ++ + + + Y++ + Y G+L +I++ +SE+++R + RQ+ +
Sbjct: 971 KNLLHQHICKLYQVIETEDHYFMVLEYCSGGELFDHIVEKSKLSESESRRFFRQIVSAVA 1030
Query: 136 YLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEI 195
YLH L HRD+K ENVLL + N+KL DFG P+ T CGS +YAAPE+
Sbjct: 1031 YLHSLGYVHRDLKPENVLLDKDQNLKLIDFGLCAKPKGGIQSPLY--TSCGSPAYAAPEL 1088
Query: 196 LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLE 255
+ G Y D+WSLGV+L+ +L +PFDD + LY++ + +Y S +S
Sbjct: 1089 ILGNKYLGSEIDIWSLGVLLYALLCGFLPFDDNNIENLYKKILNGQY----DEPSWMSQS 1144
Query: 256 CKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKEDRRKLSDV 313
+ +++ +L+ DP R + + WI L + ++ ++R +E + L V
Sbjct: 1145 SRRLIRAMLQIDPRKRITIKELCSHPWITA-GFLNPITFMKNTTVERDEEILKALKAV 1201
Score = 143 bits (346), Expect = 2e-32
Identities = 77/237 (32%), Positives = 134/237 (56%), Gaps = 12/237 (5%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ + D + L EI + L H H+ + + + YF+ + Y G+L
Sbjct: 946 VAIKIMEKAALGEDLPRVGL--EISAMKNLLHQHICKLYQVIETEDHYFMVLEYCSGGEL 1003
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ ++++ + E ++R + RQ+ A+ Y+H L HRD+K ENVLL +QN+KL DFG
Sbjct: 1004 FDHIVEKSKLSESESRRFFRQIVSAVAYLHSLGYVHRDLKPENVLLDKDQNLKLIDFG-- 1061
Query: 473 RMCVDKKLNEIRSE--TFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+C K I+S T CGS +Y APE++ G YL D+WSLG+++Y +L +PF+
Sbjct: 1062 -LCAKPK-GGIQSPLYTSCGSPAYAAPELILGNKYLGSEIDIWSLGVLLYALLCGFLPFD 1119
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
D +I+ L++ +N + S +S + +RLI ML+ + + R+ I ++ + WI
Sbjct: 1120 DNNIENLYKKILNGQYDEPS----WMSQSSRRLIRAMLQIDPRKRITIKELCSHPWI 1172
>UniRef50_UPI0000E49D63 Cluster: PREDICTED: similar to hormonally
upregulated Neu-associated kinase; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
hormonally upregulated Neu-associated kinase -
Strongylocentrotus purpuratus
Length = 962
Score = 149 bits (360), Expect = 3e-34
Identities = 93/273 (34%), Positives = 149/273 (54%), Gaps = 20/273 (7%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHK---STLACKIIETAKAPKD-FVVKFLPREIDV 74
Y L +GEG++AKV KE H +A KII+ A +D ++ K L RE +
Sbjct: 64 YLLGPTIGEGSFAKV-------KEAMHVLVGEKVAIKIIDKKAAREDAYLHKTLRREAGL 116
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
L L H H++ + + + Y+ + G LL + + G + E AR + +Q+A +
Sbjct: 117 LQLLGHTHIVRLLEVMETDNNLYLVLELCGGGPLLDRVCEKGGLEEGVARRYIKQVASAV 176
Query: 135 QYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPE 194
++H++ + HRD+K EN+LL N +++ DFG S F + + T CGS +YAAPE
Sbjct: 177 YHMHQMGVVHRDLKVENLLLDDNDKIRIIDFGLSNF-IGIFGTRDFAGTLCGSPAYAAPE 235
Query: 195 ILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF--DDTRMRKLYEQ-QMGKKYRFRSRVASI 251
I+ K Y PK D+WS+GV + ML ++PF + +R+L + Q G+ + S
Sbjct: 236 IIARKRYGPK-VDVWSIGVNAYAMLTGTLPFIVEPFNLRQLLSKIQKGE----AGPLPSG 290
Query: 252 LSLECKTVVKHLLEPDPGLRHSATNVLDSEWIA 284
LS +CK+ +++LLEPDP R + +VL W+A
Sbjct: 291 LSSDCKSFIRYLLEPDPDKRPTIYDVLCHPWLA 323
Score = 146 bits (353), Expect = 2e-33
Identities = 92/285 (32%), Positives = 151/285 (52%), Gaps = 14/285 (4%)
Query: 308 RKLSDVHKHPPKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRD- 366
++L +KH KR G L GPT + E + +K++I K+ID A D
Sbjct: 49 KELMASYKHT-KRLGPYLLGPTIGEGSFAKVKEAMHVLVGEKVAI---KIIDKKAAREDA 104
Query: 367 FVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQ 426
++ K L RE +L L H H+V + + ++ + G LL+ V ++G ++E
Sbjct: 105 YLHKTLRREAGLLQLLGHTHIVRLLEVMETDNNLYLVLELCGGGPLLDRVCEKGGLEEGV 164
Query: 427 ARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSE 486
AR + +Q+A A+ +MH++ + HRD+K EN+LL N +++ DFG + + +
Sbjct: 165 ARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDNDKIRIIDFGLSNFIGIFGTRDF-AG 223
Query: 487 TFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF--EDKHIKQLHQAQINK 544
T CGS +Y APEI+ Y PK DVWS+G+ Y ML +PF E +++QL ++K
Sbjct: 224 TLCGSPAYAAPEIIARKRYGPK-VDVWSIGVNAYAMLTGTLPFIVEPFNLRQL----LSK 278
Query: 545 NWKFRSRYIDT-ISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
K + + + +S +CK I +LEP+ R IYD++ W+A
Sbjct: 279 IQKGEAGPLPSGLSSDCKSFIRYLLEPDPDKRPTIYDVLCHPWLA 323
>UniRef50_Q95UF4 Cluster: Serine-threonine protein kinase; n=1;
Ancylostoma caninum|Rep: Serine-threonine protein kinase
- Ancylostoma caninum (Dog hookworm)
Length = 688
Score = 149 bits (360), Expect = 3e-34
Identities = 86/265 (32%), Positives = 145/265 (54%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + +G G + KV L + +A KII+ KA D + + + E+D L L
Sbjct: 10 YSIHDELGSGGFGKVKLATHLLTG----LKVAIKIIDK-KAIGDDLPR-VTTELDALRTL 63
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+H ++ ++ + K++I M Y G++ YI+K + E++AR + RQL + Y+H
Sbjct: 64 SHQNICRLYQFIDTEDKFFIIMEYCSGGEMFDYIVKKERLEESEARHFFRQLVQAMAYVH 123
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ AHRD+K EN+LLT + ++K+ DFG C + + +T CGS +YAAPE++ G
Sbjct: 124 SMGYAHRDLKPENLLLTEDLHLKVIDFG---LCAKPTSLTRPLDTCCGSPAYAAPELIAG 180
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS+GV+L+ +L S+PF+D M+ LY K R + LS ++
Sbjct: 181 KAYLGNEADIWSMGVLLYALLCGSLPFEDESMQLLYR----KIARGQYHEPEWLSPSSRS 236
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
+++ +L+ +P R + +LD WI
Sbjct: 237 LLRSMLQVNPQYRITVRQLLDHPWI 261
Score = 143 bits (346), Expect = 2e-32
Identities = 76/246 (30%), Positives = 140/246 (56%), Gaps = 10/246 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID D + + E++ L LSH ++ + K+FI M Y G++
Sbjct: 36 VAIKIIDKKAIGDDLPR--VTTELDALRTLSHQNICRLYQFIDTEDKFFIIMEYCSGGEM 93
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++++ ++E +AR + RQL A+ Y+H + AHRD+K EN+LLT + ++K+ DFG
Sbjct: 94 FDYIVKKERLEESEARHFFRQLVQAMAYVHSMGYAHRDLKPENLLLTEDLHLKVIDFG-- 151
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+C +T CGS +Y APE++ G YL D+WS+G+++Y +L ++PFED+
Sbjct: 152 -LCAKPTSLTRPLDTCCGSPAYAAPELIAGKAYLGNEADIWSMGVLLYALLCGSLPFEDE 210
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD-S 591
++ L++ K + + + +S + + L+ ML+ N Q R+ + +++ WI S
Sbjct: 211 SMQLLYR----KIARGQYHEPEWLSPSSRSLLRSMLQVNPQYRITVRQLLDHPWINHKYS 266
Query: 592 RLLEWT 597
+ L+WT
Sbjct: 267 QKLKWT 272
>UniRef50_A2EP88 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 371
Score = 149 bits (360), Expect = 3e-34
Identities = 86/265 (32%), Positives = 138/265 (52%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y L + VG+G V D H + ACKII K +K E+ V+ L
Sbjct: 15 YYLEEIVGQGNTCVVV-----KARDIHDNVFACKIISKLKFSSATNIKHFQDELAVMRTL 69
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP++I++ I Q YIF Y E GDL IL++ C+ E++A Q+ GL ++H
Sbjct: 70 SHPNIINLVEILQDSNNVYIFEEYCELGDLTREILRSKCIEEDRAGSIMTQVFKGLSFMH 129
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ IAHRDIK EN+ + +N +K++DFG+S +D + T CG++ Y APEIL+
Sbjct: 130 QHHIAHRDIKPENIFVCSNGLIKVADFGYSTLNSGTDYR----STVCGTLIYIAPEILKQ 185
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
PY D WS GV+L+ M+ +P++ + E+ KK + +S EC+
Sbjct: 186 TPYNALIADAWSCGVLLYAMVCGYLPWEKKSQAGMTEEIKFKKIEY----PETMSPECRY 241
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
+++HL + + R S ++ ++I
Sbjct: 242 LIEHLCDRNVDTRFSIAQAMECDFI 266
Score = 134 bits (325), Expect = 5e-30
Identities = 78/238 (32%), Positives = 127/238 (53%), Gaps = 10/238 (4%)
Query: 351 SILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERG 410
++ ACK+I K E+ ++ LSHP++++ I Q +IF Y E G
Sbjct: 38 NVFACKIISKLKFSSATNIKHFQDELAVMRTLSHPNIINLVEILQDSNNVYIFEEYCELG 97
Query: 411 DLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFG 470
DL +L+ ++ED+A Q+ + +MH+ IAHRDIK EN+ + +N +K++DFG
Sbjct: 98 DLTREILRSKCIEEDRAGSIMTQVFKGLSFMHQHHIAHRDIKPENIFVCSNGLIKVADFG 157
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
++ + + RS T CG+L Y APEIL+ TPY D WS G+++Y M+ +P+E
Sbjct: 158 YSTL---NSGTDYRS-TVCGTLIYIAPEILKQTPYNALIADAWSCGVLLYAMVCGYLPWE 213
Query: 531 DKHIKQLHQAQINKNWKFRS-RYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
K QA + + KF+ Y +T+S C+ LI + + N R I + ++I
Sbjct: 214 KK-----SQAGMTEEIKFKKIEYPETMSPECRYLIEHLCDRNVDTRFSIAQAMECDFI 266
>UniRef50_Q7Z865 Cluster: Protein kinase; n=1; Kluyveromyces
lactis|Rep: Protein kinase - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 1267
Score = 149 bits (360), Expect = 3e-34
Identities = 87/268 (32%), Positives = 154/268 (57%), Gaps = 18/268 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP----REIDV 74
+KL K +G+G+ +V L + + E S A KI+ K K +K LP REI +
Sbjct: 73 WKLGKTLGKGSSGRVRLAK--NMETGKLS--AIKIVPK-KFVKSNQIKQLPYGIEREIII 127
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
+ ++HP+++ ++ +++ K++ Y+ + Y E G+L Y++ G + E++A + +Q+ +
Sbjct: 128 MKLISHPNVMGLYEVWENKSELYLVLEYVEGGELFDYLVSKGKLPESEAIHYFKQIVQAV 187
Query: 135 QYLHELEIAHRDIKCENVLL-TANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAP 193
Y H I HRD+K EN+LL ++K++DFG + +E+ ++ L ET CGS YA+P
Sbjct: 188 AYCHGFNICHRDLKPENLLLDKKKRSIKIADFGMA--ALETSDK--LLETSCGSPHYASP 243
Query: 194 EILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILS 253
EI+ G+ Y P+D+WS G++LF +L +PF+D ++KL + KY ++ LS
Sbjct: 244 EIVLGRKYHGSPSDVWSCGIILFALLTGHLPFNDDNVKKLLLKVQSGKY----QMPQWLS 299
Query: 254 LECKTVVKHLLEPDPGLRHSATNVLDSE 281
+E K ++ +L DP R + +L E
Sbjct: 300 VEAKDLISRILVVDPNRRITIDQILQHE 327
Score = 130 bits (313), Expect = 2e-28
Identities = 75/255 (29%), Positives = 140/255 (54%), Gaps = 11/255 (4%)
Query: 332 SAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTH 391
S+ RV LA+ K + I+ K + ++ + + + REI ++ +SHP+++ +
Sbjct: 83 SSGRVRLAKNMETGKLSAIKIVPKKFVKSNQIKQ--LPYGIEREIIIMKLISHPNVMGLY 140
Query: 392 SIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDI 451
+++ + + ++ + Y+E G+L ++++ +G + E +A + +Q+ A+ Y H I HRD+
Sbjct: 141 EVWENKSELYLVLEYVEGGELFDYLVSKGKLPESEAIHYFKQIVQAVAYCHGFNICHRDL 200
Query: 452 KCENVLL-TANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPT 510
K EN+LL +++K++DFG A + KL ET CGS Y +PEI+ G Y P+
Sbjct: 201 KPENLLLDKKKRSIKIADFGMAALETSDKL----LETSCGSPHYASPEIVLGRKYHGSPS 256
Query: 511 DVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEP 570
DVWS GI+++ +L +PF D ++K+L + K + + +S K LI +L
Sbjct: 257 DVWSCGIILFALLTGHLPFNDDNVKKL----LLKVQSGKYQMPQWLSVEAKDLISRILVV 312
Query: 571 NHQNRLKIYDIVNSE 585
+ R+ I I+ E
Sbjct: 313 DPNRRITIDQILQHE 327
>UniRef50_A7TMR5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 1225
Score = 149 bits (360), Expect = 3e-34
Identities = 77/214 (35%), Positives = 118/214 (55%), Gaps = 8/214 (3%)
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
RE + L HPH+ + + +Y+ Y G LL YI+++G + E+ AR + R
Sbjct: 218 REASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLREHHARRFARG 277
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
+A LQYLH I HRD+K EN++++ + +KL DFG S DN+ L T+CGS+
Sbjct: 278 IASALQYLHANNIVHRDLKIENIMISTSGEIKLIDFGLSNL---YDNRKQL-HTFCGSLY 333
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
+AAPE+L+ PY D+WS GVVL+V++ +PFDD L+E+ K +
Sbjct: 334 FAAPELLKANPYTGPEVDVWSFGVVLYVLVCGKVPFDDENSSVLHEKIKQGKVEYSQH-- 391
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
LS+E +++ +L DP R S V+D W+
Sbjct: 392 --LSIEVISLLSKMLVVDPKRRASLKQVVDHHWM 423
Score = 138 bits (335), Expect = 3e-31
Identities = 68/214 (31%), Positives = 120/214 (56%), Gaps = 8/214 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE + L HPH+ + +++ Y+ G LL++++Q G+++E AR + R
Sbjct: 218 REASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLREHHARRFARG 277
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+A A+QY+H I HRD+K EN++++ + +KL DFG + + ++K + TFCGSL
Sbjct: 278 IASALQYLHANNIVHRDLKIENIMISTSGEIKLIDFGLSNLYDNRK----QLHTFCGSLY 333
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
+ APE+L+ PY DVWS G+V+YV++ +PF+D++ LH+ K + + Y
Sbjct: 334 FAAPELLKANPYTGPEVDVWSFGVVLYVLVCGKVPFDDENSSVLHE----KIKQGKVEYS 389
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+S L+ ML + + R + +V+ W+
Sbjct: 390 QHLSIEVISLLSKMLVVDPKRRASLKQVVDHHWM 423
>UniRef50_P45894 Cluster: 5'-AMP-activated protein kinase catalytic
subunit alpha-1; n=3; Caenorhabditis|Rep:
5'-AMP-activated protein kinase catalytic subunit
alpha-1 - Caenorhabditis elegans
Length = 589
Score = 149 bits (360), Expect = 3e-34
Identities = 83/271 (30%), Positives = 137/271 (50%), Gaps = 18/271 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKST---LACKIIETAKAPKDFVVKFLPREIDVL 75
+ + + +G+GA+ V K +H T +A KI+ + V EID L
Sbjct: 24 FVIKETIGKGAFGAV-------KRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNL 76
Query: 76 VRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQ 135
+L HPH+ + + + ++ M G+L SYI + G + ++R + +Q+ G+
Sbjct: 77 QKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVS 136
Query: 136 YLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEI 195
Y H I HRD+K EN+LL AN N+K++DFG S + + D L T CGS +YAAPE+
Sbjct: 137 YCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGD----LLSTACGSPNYAAPEL 192
Query: 196 LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLE 255
+ K Y DLWS GV+L+ ML ++PFDD + L+ + +Y V + +
Sbjct: 193 ISNKLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRY----TVPYSMEKQ 248
Query: 256 CKTVVKHLLEPDPGLRHSATNVLDSEWIAMD 286
++ +L+ DP R +++ W +D
Sbjct: 249 AADLISTMLQVDPVKRADVKRIVNHSWFRID 279
Score = 134 bits (323), Expect = 9e-30
Identities = 70/216 (32%), Positives = 118/216 (54%), Gaps = 8/216 (3%)
Query: 375 EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQL 434
EI+ L KL+HPH+ + F+ M + G+L ++ ++GA+ ++R + +Q+
Sbjct: 72 EIDNLQKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQI 131
Query: 435 ALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSY 494
+ Y H I HRD+K EN+LL AN+N+K++DFG + D L T CGS +Y
Sbjct: 132 ISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDL----LSTACGSPNY 187
Query: 495 TAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYID 554
APE++ Y+ D+WS G+++Y ML +PF+D+++ L A+I K+ ++ Y
Sbjct: 188 AAPELISNKLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLF-AKI-KSGRYTVPY-- 243
Query: 555 TISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
++ LI ML+ + R + IVN W +D
Sbjct: 244 SMEKQAADLISTMLQVDPVKRADVKRIVNHSWFRID 279
>UniRef50_UPI0000583D61 Cluster: PREDICTED: similar to Tssk5
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Tssk5 protein - Strongylocentrotus
purpuratus
Length = 228
Score = 148 bits (359), Expect = 4e-34
Identities = 84/213 (39%), Positives = 123/213 (57%), Gaps = 21/213 (9%)
Query: 18 GYKLTKF-VGEGAYAKVYLTEYSSKEDSHKSTL------------ACKIIETAKAPKDFV 64
GY LT +G G YAKV L ++ + + L A KII AP +++
Sbjct: 18 GYILTDMTLGSGTYAKVKLARAMKRKIAQTAKLRDDLRIKGHNMVAIKIISRRDAPTEYL 77
Query: 65 VKFLPREIDVL-VRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYI----LKNG-CV 118
KF+PREID + + H HLI ++ F+ + Y+ + Y +GD+LSYI + G V
Sbjct: 78 KKFMPREIDAMRITHKHAHLIQLYEFFRSERGVYLVLEYAAHGDVLSYINDSVQETGMAV 137
Query: 119 SENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQP 178
E++AR RQ+ G+ + H+ + HRD+KCEN++L N+NVK+SDFGF+ C N+
Sbjct: 138 EEDKARQLFRQIVSGVTFCHDRNVVHRDLKCENIILDENWNVKISDFGFA--CRFPSNRC 195
Query: 179 VLSETYCGSMSYAAPEILRGKPYCPKPTDLWSL 211
+ T+CGS +YAAPEI+ GK Y K D+WSL
Sbjct: 196 NMLSTFCGSYAYAAPEIMAGKNYDGKLADVWSL 228
Score = 138 bits (334), Expect = 4e-31
Identities = 70/171 (40%), Positives = 103/171 (60%), Gaps = 8/171 (4%)
Query: 351 SILACKVIDTSTAPRDFVKKFLPREIE-MLIKLSHPHLVHTHSIFQRRYKYFIFMRYMER 409
+++A K+I AP +++KKF+PREI+ M I H HL+ + F+ ++ + Y
Sbjct: 60 NMVAIKIISRRDAPTEYLKKFMPREIDAMRITHKHAHLIQLYEFFRSERGVYLVLEYAAH 119
Query: 410 GDLLEF----VLQRG-AVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNV 464
GD+L + V + G AV+ED+AR RQ+ + + H+ + HRD+KCEN++L N NV
Sbjct: 120 GDVLSYINDSVQETGMAVEEDKARQLFRQIVSGVTFCHDRNVVHRDLKCENIILDENWNV 179
Query: 465 KLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSL 515
K+SDFGFA + N + TFCGS +Y APEI+ G Y K DVWSL
Sbjct: 180 KISDFGFACRFPSNRCNML--STFCGSYAYAAPEIMAGKNYDGKLADVWSL 228
>UniRef50_UPI000023D36F Cluster: hypothetical protein FG08701.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG08701.1 - Gibberella zeae PH-1
Length = 1112
Score = 148 bits (359), Expect = 4e-34
Identities = 69/204 (33%), Positives = 122/204 (59%), Gaps = 7/204 (3%)
Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127
+ RE+ +L + HPH++ ++ I++ +++ Y+ + Y + GDL ++I G +SE + +
Sbjct: 184 IEREVAILKLIEHPHIMKIYDIWENRSEVYLILEYIDQGDLFTFINMKGRLSEEVSVYFF 243
Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187
RQ+ + Y H I HRD+K EN+L++AN +K++DFG + ++D + T CGS
Sbjct: 244 RQIISAISYCHSFNICHRDLKPENILISANLKIKIADFGMAAL-HQTDTHRL--NTACGS 300
Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSR 247
YAAPE+L+ + Y DLWS+GV+LF ML ++PFDD +R + M K + +
Sbjct: 301 PHYAAPELLKNRQYRGDKADLWSMGVILFAMLTATLPFDDPDIRVM----MSKTKKGQYE 356
Query: 248 VASILSLECKTVVKHLLEPDPGLR 271
+ LS E + +++ +L+ +P R
Sbjct: 357 MPDYLSPEAEDLIRRMLQVNPDRR 380
Score = 143 bits (347), Expect = 1e-32
Identities = 68/210 (32%), Positives = 121/210 (57%), Gaps = 7/210 (3%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ RE+ +L + HPH++ + I++ R + ++ + Y+++GDL F+ +G + E+ + +
Sbjct: 184 IEREVAILKLIEHPHIMKIYDIWENRSEVYLILEYIDQGDLFTFINMKGRLSEEVSVYFF 243
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
RQ+ AI Y H I HRD+K EN+L++AN +K++DFG A + + + R T CGS
Sbjct: 244 RQIISAISYCHSFNICHRDLKPENILISANLKIKIADFGMAAL---HQTDTHRLNTACGS 300
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y APE+L+ Y D+WS+G++++ ML +PF+D I+ ++K K +
Sbjct: 301 PHYAAPELLKNRQYRGDKADLWSMGVILFAMLTATLPFDDPDIR----VMMSKTKKGQYE 356
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKIYDI 581
D +S + LI ML+ N R+ + +I
Sbjct: 357 MPDYLSPEAEDLIRRMLQVNPDRRITLKEI 386
>UniRef50_A5K3L6 Cluster: Serine/threonine-protein kinase, putative;
n=1; Plasmodium vivax|Rep: Serine/threonine-protein
kinase, putative - Plasmodium vivax
Length = 861
Score = 148 bits (359), Expect = 4e-34
Identities = 86/269 (31%), Positives = 144/269 (53%), Gaps = 13/269 (4%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
L K Y +T +G+G + KV L + + +A KI+ K + + + +EI +
Sbjct: 477 LRKEYLITSQIGKGTFGKVCLGIHIHTHE----IVAIKILNKKKLQRLISYEKIMKEIKI 532
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGC-VSENQARVWTRQLALG 133
+++H H+ ++ ++ + Y+ + Y NGDLL+Y+ K ++E+ AR QL
Sbjct: 533 HEQMDHNHICKLYEAYEDRKYIYMILEYVSNGDLLAYVCKKKRRINEDTARRIFYQLISA 592
Query: 134 LQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAP 193
+ YLH+ + HRD+K EN+LL N+KL DFG S E +N L T CGS Y +P
Sbjct: 593 VDYLHKFNVVHRDLKPENILLDDEENIKLIDFGLSTV-YEKNN---LLTTSCGSPFYTSP 648
Query: 194 EILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILS 253
EIL G Y + TD+WSLGV+LF++LN+ +PF+ T + L+++ + F + S
Sbjct: 649 EILLGNKYHGELTDVWSLGVILFLLLNRKLPFNHTNLNVLFQEIIKGLLHFEPHI----S 704
Query: 254 LECKTVVKHLLEPDPGLRHSATNVLDSEW 282
K +++++L + R+S V W
Sbjct: 705 EGAKNLIRNMLNVNFQKRYSLREVKTHPW 733
Score = 142 bits (344), Expect = 3e-32
Identities = 80/236 (33%), Positives = 129/236 (54%), Gaps = 9/236 (3%)
Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
I+A K+++ R + + +EI++ ++ H H+ + ++ R ++ + Y+ GD
Sbjct: 506 IVAIKILNKKKLQRLISYEKIMKEIKIHEQMDHNHICKLYEAYEDRKYIYMILEYVSNGD 565
Query: 412 LLEFVLQRGA-VQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFG 470
LL +V ++ + ED AR QL A+ Y+H+ + HRD+K EN+LL +N+KL DFG
Sbjct: 566 LLAYVCKKKRRINEDTARRIFYQLISAVDYLHKFNVVHRDLKPENILLDDEENIKLIDFG 625
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
+ V +K N + T CGS YT+PEIL G Y + TDVWSLG++++++LNR +PF
Sbjct: 626 LST--VYEKNNLLT--TSCGSPFYTSPEILLGNKYHGELTDVWSLGVILFLLLNRKLPFN 681
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
++ L Q I F IS+ K LI ML N Q R + ++ W
Sbjct: 682 HTNLNVLFQEIIKGLLHFEPH----ISEGAKNLIRNMLNVNFQKRYSLREVKTHPW 733
>UniRef50_A2FGW3 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 495
Score = 148 bits (359), Expect = 4e-34
Identities = 86/260 (33%), Positives = 136/260 (52%), Gaps = 15/260 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAK-APKDFVVKFLPREIDVLVR 77
Y + + +G G+ KV L ++ A KII+ + K + + + RE+ V+
Sbjct: 10 YVVERVLGSGSCGKVKL----ARNMQTGQFAAIKIIKKSFFESKPNIKEKIQREVAVMRI 65
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
H L+ + I + Y+ + Y NG+L Y++ GC+SE +A + RQ+ G+ +L
Sbjct: 66 FKHSRLLKLLEICESPHHIYLVLEYASNGELFDYLISRGCLSEAEAMHFFRQIIFGIDFL 125
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H I HRDIK EN+LL + N+K++DFGF+R + + P+ TYCGS+ YAAPEI+
Sbjct: 126 HSRSICHRDIKPENLLLDEHNNIKIADFGFARI---ASSDPL--TTYCGSIYYAAPEIVN 180
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
G PY P D+WS G+VL+ +L +PF D RK E+ Y V +S
Sbjct: 181 GVPYHGFPADIWSCGIVLYTLLTGKLPFQDPAYRKTVEKIKSGHY-----VMPDVSDPIN 235
Query: 258 TVVKHLLEPDPGLRHSATNV 277
++ + L DP R + +
Sbjct: 236 DLLANCLNSDPNSRFTTAQI 255
Score = 134 bits (323), Expect = 9e-30
Identities = 60/164 (36%), Positives = 97/164 (59%), Gaps = 5/164 (3%)
Query: 368 VKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQA 427
+K+ + RE+ ++ H L+ I + + ++ + Y G+L ++++ RG + E +A
Sbjct: 52 IKEKIQREVAVMRIFKHSRLLKLLEICESPHHIYLVLEYASNGELFDYLISRGCLSEAEA 111
Query: 428 RIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSET 487
+ RQ+ I ++H I HRDIK EN+LL + N+K++DFGFAR+ L T
Sbjct: 112 MHFFRQIIFGIDFLHSRSICHRDIKPENLLLDEHNNIKIADFGFARIASSDPLT-----T 166
Query: 488 FCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+CGS+ Y APEI+ G PY P D+WS GIV+Y +L +PF+D
Sbjct: 167 YCGSIYYAAPEIVNGVPYHGFPADIWSCGIVLYTLLTGKLPFQD 210
>UniRef50_A2EKR5 Cluster: CAMK family protein kinase; n=3;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 527
Score = 148 bits (359), Expect = 4e-34
Identities = 89/261 (34%), Positives = 146/261 (55%), Gaps = 17/261 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETA--KAPKDFVVKFLPREIDVLV 76
Y + +G+G KV L + + H +A KI++ + + + VK + REI ++
Sbjct: 12 YHFIRQIGQGTTGKVKLA-FDKVNNRH---VAVKIVKKSLFQNRPNLEVK-IQREIALMR 66
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
++HPHL+ + I + YI Y G+L Y++++ + E+ A + RQ+ GL+Y
Sbjct: 67 LVDHPHLLKLIDILESPRHLYIVTDYAVKGELFDYLVQHRFLPEDVAMNFFRQIIYGLEY 126
Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
LH L I HRD+K EN+LL N N+K++DFGF+R V+S+ ++ T CGS YAAPE++
Sbjct: 127 LHSLGICHRDLKPENILLDENLNIKIADFGFAR-VVKSN----IASTSCGSPHYAAPEVI 181
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
+G+PY + D+WS GV+L+ +L +PFDD +R L +GK R +
Sbjct: 182 KGEPYDGRAADVWSCGVILYALLAGFLPFDDPNIRVL----LGKVKRGLYTMPQ-FPTRV 236
Query: 257 KTVVKHLLEPDPGLRHSATNV 277
K +++ +L DP R S +
Sbjct: 237 KDLIRGMLTIDPTKRISIAQI 257
Score = 133 bits (322), Expect = 1e-29
Identities = 64/166 (38%), Positives = 102/166 (61%), Gaps = 5/166 (3%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ REI ++ + HPHL+ I + +I Y +G+L ++++Q + ED A +
Sbjct: 58 IQREIALMRLVDHPHLLKLIDILESPRHLYIVTDYAVKGELFDYLVQHRFLPEDVAMNFF 117
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
RQ+ ++Y+H L I HRD+K EN+LL N N+K++DFGFAR+ K N + T CGS
Sbjct: 118 RQIIYGLEYLHSLGICHRDLKPENILLDENLNIKIADFGFARVV---KSN--IASTSCGS 172
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQL 537
Y APE+++G PY + DVWS G+++Y +L +PF+D +I+ L
Sbjct: 173 PHYAAPEVIKGEPYDGRAADVWSCGVILYALLAGFLPFDDPNIRVL 218
>UniRef50_P57058 Cluster: Hormonally up-regulated neu
tumor-associated kinase; n=26; Eumetazoa|Rep: Hormonally
up-regulated neu tumor-associated kinase - Homo sapiens
(Human)
Length = 714
Score = 148 bits (359), Expect = 4e-34
Identities = 91/265 (34%), Positives = 146/265 (55%), Gaps = 18/265 (6%)
Query: 25 VGEGAYAKVYLTEYSSKEDSHKST---LACKIIETAKAPKD-FVVKFLPREIDVLVRLNH 80
+GEG++AKV +E H T +A K+I+ +A KD +V K L RE + + H
Sbjct: 68 LGEGSFAKV-------REGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRH 120
Query: 81 PHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHEL 140
P++ + I + + YY+ M G+L+ I + + E++AR + RQL +++LH
Sbjct: 121 PNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRA 180
Query: 141 EIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKP 200
+ HRD+K EN+LL + N+KL DFG S C T CGS +YAAPE+L K
Sbjct: 181 GVVHRDLKIENLLLDEDNNIKLIDFGLSN-CAGILGYSDPFSTQCGSPAYAAPELLARKK 239
Query: 201 YCPKPTDLWSLGVVLFVMLNKSMPF--DDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y PK D+WS+GV ++ ML ++PF + +R LY++ + K+ + + + LS +
Sbjct: 240 YGPK-IDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKE---MNPLPTQLSTGAIS 295
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
++ LLEPDP R + L + W+
Sbjct: 296 FLRSLLEPDPVKRPNIQQALANRWL 320
Score = 131 bits (317), Expect = 5e-29
Identities = 88/286 (30%), Positives = 145/286 (50%), Gaps = 16/286 (5%)
Query: 307 RRKLSDVHKHPPKRQGDILEGPTR--ESAFRVYLAEYRNASKNDKLSILACKVIDTSTAP 364
R +L D H KR G+ L G + E +F + E + +K++I KVID A
Sbjct: 46 RERLRDFQHH--KRVGNYLIGSRKLGEGSF-AKVREGLHVLTGEKVAI---KVIDKKRAK 99
Query: 365 RD-FVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQ 423
+D +V K L RE ++ + HP++ I + Y++ M G+L+ + ++ ++
Sbjct: 100 KDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLE 159
Query: 424 EDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEI 483
E +AR + RQL A++++H + HRD+K EN+LL + N+KL DFG + C
Sbjct: 160 ESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSN-CAGILGYSD 218
Query: 484 RSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF--EDKHIKQLHQAQ 541
T CGS +Y APE+L Y PK DVWS+G+ +Y ML +PF E ++ L+Q
Sbjct: 219 PFSTQCGSPAYAAPELLARKKYGPK-IDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKM 277
Query: 542 INKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
++K + +S + +LEP+ R I + + W+
Sbjct: 278 VDKE---MNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWL 320
>UniRef50_UPI00002495CF Cluster: PREDICTED: similar to NUAK family,
SNF1-like kinase, 1; n=1; Danio rerio|Rep: PREDICTED:
similar to NUAK family, SNF1-like kinase, 1 - Danio
rerio
Length = 452
Score = 148 bits (358), Expect = 5e-34
Identities = 88/278 (31%), Positives = 150/278 (53%), Gaps = 14/278 (5%)
Query: 313 VHKHPPKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFL 372
+HKH KR+ ++LE R + +V A R K +A K I D + +
Sbjct: 25 LHKHSLKRRFEVLETLGRGTYGKVKRAVERQYGKT-----VAIKSIRKERLRNDLDRAHI 79
Query: 373 PREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTR 432
REIE+ L HP+++ + +F+ R + + M Y G+L E++ + + ED+AR + R
Sbjct: 80 QREIEITSSLVHPNIIRLYEVFESRERIVMVMEYASGGELYEYIQDKQRLSEDEARHFFR 139
Query: 433 QLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSL 492
Q+ A+ Y H+ + HRD+K EN+LL + VKL+DFG + ++ + +TFCGS
Sbjct: 140 QITSAVHYCHQNGVVHRDLKLENILLDKDLTVKLADFGLS----NRYMRGRCLDTFCGSP 195
Query: 493 SYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRY 552
Y +PEI+ G PY D WSLG+++Y ++ +MPF+ + L + QI ++ +++
Sbjct: 196 LYASPEIINGLPYHGPEVDCWSLGVLLYALVYGSMPFDGTNYSILKE-QI-RHGLYKTPN 253
Query: 553 IDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD 590
I S+ C LI ML ++R + DI + W+ ++
Sbjct: 254 IP--SEACS-LIEWMLTVKVEDRATVEDIASHWWLNLN 288
Score = 145 bits (352), Expect = 3e-33
Identities = 77/222 (34%), Positives = 121/222 (54%), Gaps = 8/222 (3%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
L + +++ + +G G Y KV + E + T+A K I + D + REI++
Sbjct: 30 LKRRFEVLETLGRGTYGKVK----RAVERQYGKTVAIKSIRKERLRNDLDRAHIQREIEI 85
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
L HP++I ++ +F+ + + + M Y G+L YI +SE++AR + RQ+ +
Sbjct: 86 TSSLVHPNIIRLYEVFESRERIVMVMEYASGGELYEYIQDKQRLSEDEARHFFRQITSAV 145
Query: 135 QYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPE 194
Y H+ + HRD+K EN+LL + VKL+DFG S + +T+CGS YA+PE
Sbjct: 146 HYCHQNGVVHRDLKLENILLDKDLTVKLADFGLSNRYMRGR----CLDTFCGSPLYASPE 201
Query: 195 ILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ 236
I+ G PY D WSLGV+L+ ++ SMPFD T L EQ
Sbjct: 202 IINGLPYHGPEVDCWSLGVLLYALVYGSMPFDGTNYSILKEQ 243
>UniRef50_Q170I9 Cluster: Serine/threonine protein kinase; n=3;
Culicidae|Rep: Serine/threonine protein kinase - Aedes
aegypti (Yellowfever mosquito)
Length = 543
Score = 148 bits (358), Expect = 5e-34
Identities = 80/264 (30%), Positives = 138/264 (52%), Gaps = 11/264 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+ +G G +++V L + +D +A K+++T++ ++ L +E+ L
Sbjct: 10 YRFCGDIGRGNFSRVKLAVHQLTKDK----VAIKVVDTSRLDAK-ALRMLSKEVSTLEAA 64
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP ++ + + K Y+ + G+L S I+ G + E A V QL + ++YLH
Sbjct: 65 FHPFILRLFEVIDTIGKIYLVSEWIPGGELYSRIVDIGALEEYHAAVIFYQLLIAVKYLH 124
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
L HRDIK EN+L+ +KL+DFGFS + NQ + +T+CGS YAAPE+
Sbjct: 125 SLGYVHRDIKAENILMINEERIKLADFGFSTQLINGSNQHL--DTFCGSPPYAAPELFSD 182
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y P D+W+LG++L+ ML+ MPF + + L + +Y +++ LSL C
Sbjct: 183 DHYVGGPVDIWALGILLYFMLHARMPFKGSTIPLLRTAVLKGEY----EISTSLSLSCCR 238
Query: 259 VVKHLLEPDPGLRHSATNVLDSEW 282
+++ +L P R S +L+ +W
Sbjct: 239 LIQRILVNSPFRRPSMDQLLECQW 262
Score = 134 bits (323), Expect = 9e-30
Identities = 71/234 (30%), Positives = 125/234 (53%), Gaps = 7/234 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KV+DTS ++ L +E+ L HP ++ + K ++ ++ G+L
Sbjct: 36 VAIKVVDTSRLDAKALR-MLSKEVSTLEAAFHPFILRLFEVIDTIGKIYLVSEWIPGGEL 94
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++ GA++E A + QL +A++Y+H L HRDIK EN+L+ + +KL+DFGF+
Sbjct: 95 YSRIVDIGALEEYHAAVIFYQLLIAVKYLHSLGYVHRDIKAENILMINEERIKLADFGFS 154
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
++ + +TFCGS Y APE+ Y+ P D+W+LGI++Y ML+ MPF+
Sbjct: 155 TQLINGSNQHL--DTFCGSPPYAAPELFSDDHYVGGPVDIWALGILLYFMLHARMPFKGS 212
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
I L A + ++ + ++S +C RLI +L + R + ++ +W
Sbjct: 213 TIPLLRTAVLKGEYEIST----SLSLSCCRLIQRILVNSPFRRPSMDQLLECQW 262
>UniRef50_Q7SCT1 Cluster: Putative uncharacterized protein
NCU09064.1; n=2; Sordariales|Rep: Putative
uncharacterized protein NCU09064.1 - Neurospora crassa
Length = 1233
Score = 148 bits (358), Expect = 5e-34
Identities = 72/201 (35%), Positives = 117/201 (58%), Gaps = 7/201 (3%)
Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127
+ RE+ +L + HP++I +H I++ + Y+ Y E GDL +I NG ++E +A +
Sbjct: 194 IEREVAILKLIQHPNIIKLHDIWENRQDIYLVTEYVEKGDLFDFINWNGSLNEEEAIFYY 253
Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187
RQ+ L+Y H I HRD+K EN+LL A+ +K++DFG + E + +T CGS
Sbjct: 254 RQIMSALEYCHSFNICHRDLKPENILLKADGQIKIADFGMAALHQEPTHH---LKTACGS 310
Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSR 247
YAAPE+L+ +PY D+W++GV+LF ML +PFDD+ M + ++ Y+ S
Sbjct: 311 PHYAAPELLKHQPYKGSAVDIWAMGVILFAMLAGRLPFDDSDMDAMLQRARKGYYKMPSE 370
Query: 248 VASILSLECKTVVKHLLEPDP 268
LS E K +++ +L +P
Sbjct: 371 ----LSREAKDLIRKILVVNP 387
Score = 136 bits (328), Expect = 2e-30
Identities = 66/205 (32%), Positives = 116/205 (56%), Gaps = 7/205 (3%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ RE+ +L + HP+++ H I++ R ++ Y+E+GDL +F+ G++ E++A +
Sbjct: 194 IEREVAILKLIQHPNIIKLHDIWENRQDIYLVTEYVEKGDLFDFINWNGSLNEEEAIFYY 253
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
RQ+ A++Y H I HRD+K EN+LL A+ +K++DFG A + + + +T CGS
Sbjct: 254 RQIMSALEYCHSFNICHRDLKPENILLKADGQIKIADFGMAALHQEPTHH---LKTACGS 310
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y APE+L+ PY D+W++G++++ ML +PF+D + + Q +K S
Sbjct: 311 PHYAAPELLKHQPYKGSAVDIWAMGVILFAMLAGRLPFDDSDMDAMLQRARKGYYKMPSE 370
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRL 576
+S K LI +L N R+
Sbjct: 371 ----LSREAKDLIRKILVVNPLQRI 391
>UniRef50_Q6CUX0 Cluster: Similar to sp|Q12263 Saccharomyces
cerevisiae YDR507c GIN4 ser/thr protein kinase; n=2;
Saccharomycetales|Rep: Similar to sp|Q12263
Saccharomyces cerevisiae YDR507c GIN4 ser/thr protein
kinase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 1112
Score = 148 bits (358), Expect = 5e-34
Identities = 91/270 (33%), Positives = 145/270 (53%), Gaps = 17/270 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPK-------DFVVKFLPRE 71
+KL +G G+ KV + +K + K I A+ D + + RE
Sbjct: 17 WKLGSTLGVGSTGKVVMAYNETKGQQAAVKIISKSIFNAQGSTMIGGNDPDVLPYGIERE 76
Query: 72 IDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLA 131
I ++ LNHP+++ ++ +++ Y+ + Y E G+L + +++ G + EN+A + RQ+
Sbjct: 77 IIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFFRQII 136
Query: 132 LGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYA 191
+G+ Y H L I HRD+K EN+LL FNVKL+DFG + +ES ++ L ET CGS YA
Sbjct: 137 IGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMA--ALESKDK--LLETSCGSPHYA 192
Query: 192 APEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFD--DTRMRK-LYEQQMGKKYRFRSRV 248
APEI+ G PY +D+WS GV+L+ +L +PFD D +R L + Q GK F
Sbjct: 193 APEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKVQSGK---FEMPG 249
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVL 278
+S E + ++ +L DP R +L
Sbjct: 250 DDEISSEAQDLIARILTVDPEQRIKTREIL 279
Score = 137 bits (332), Expect = 8e-31
Identities = 76/213 (35%), Positives = 124/213 (58%), Gaps = 8/213 (3%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ REI ++ L+HP+++ + +++ ++ + Y+E+G+L +++RG + E++A +
Sbjct: 73 IEREIIIMKLLNHPNVLRLYDVWETSKDLYMVLEYVEKGELFNLLVERGPLPENEAVRFF 132
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
RQ+ + I Y H L I HRD+K EN+LL NVKL+DFG A + KL ET CGS
Sbjct: 133 RQIIIGISYCHALGIVHRDLKPENLLLDHKFNVKLADFGMAALESKDKL----LETSCGS 188
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF--EDKHIKQLHQAQINKNWKFR 549
Y APEI+ G PY +DVWS G+++Y +L +PF ED +I+ L ++ KF
Sbjct: 189 PHYAAPEIVSGLPYHGFESDVWSCGVILYALLTGRLPFDEEDGNIRNLLLKV--QSGKFE 246
Query: 550 SRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIV 582
D IS + LI +L + + R+K +I+
Sbjct: 247 MPGDDEISSEAQDLIARILTVDPEQRIKTREIL 279
>UniRef50_Q6BR88 Cluster: Similar to CA5851|CaKIN2 Candida albicans
CaKIN2; n=2; Saccharomycetaceae|Rep: Similar to
CA5851|CaKIN2 Candida albicans CaKIN2 - Debaryomyces
hansenii (Yeast) (Torulaspora hansenii)
Length = 1296
Score = 148 bits (358), Expect = 5e-34
Identities = 74/206 (35%), Positives = 113/206 (54%), Gaps = 8/206 (3%)
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
L HP + ++ + YY+ Y E G +L YI+ +G + E AR + R +AL L+Y
Sbjct: 315 LFHPFICRLYEMVPMTNHYYMLFEYVEGGQMLDYIVSHGSLKEKNARKFARGIALALEYC 374
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H + HRD+K EN+++ + ++K+ DFG S + L +TYCGS+ +AAPE+L
Sbjct: 375 HSNNVVHRDLKIENIMINSKGDIKIIDFGLSNLY----SPKSLLKTYCGSLYFAAPELLS 430
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
KPY D+WS GVVL+V++ +PFDD + L+E K R S LS EC
Sbjct: 431 AKPYTGPEVDVWSFGVVLYVLVCGKVPFDDQSVSILHE----KIKRGNVEYPSFLSKECV 486
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWI 283
+++ +L DP R S V+ W+
Sbjct: 487 SLLSRMLVVDPTKRASLFEVVQHPWM 512
Score = 140 bits (340), Expect = 8e-32
Identities = 64/206 (31%), Positives = 115/206 (55%), Gaps = 8/206 (3%)
Query: 382 LSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYM 441
L HP + + + Y++ Y+E G +L++++ G+++E AR + R +ALA++Y
Sbjct: 315 LFHPFICRLYEMVPMTNHYYMLFEYVEGGQMLDYIVSHGSLKEKNARKFARGIALALEYC 374
Query: 442 HELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQ 501
H + HRD+K EN+++ + ++K+ DFG + + K L +T+CGSL + APE+L
Sbjct: 375 HSNNVVHRDLKIENIMINSKGDIKIIDFGLSNLYSPKSL----LKTYCGSLYFAAPELLS 430
Query: 502 GTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCK 561
PY DVWS G+V+YV++ +PF+D+ + LH+ K + Y +S C
Sbjct: 431 AKPYTGPEVDVWSFGVVLYVLVCGKVPFDDQSVSILHE----KIKRGNVEYPSFLSKECV 486
Query: 562 RLIGLMLEPNHQNRLKIYDIVNSEWI 587
L+ ML + R ++++V W+
Sbjct: 487 SLLSRMLVVDPTKRASLFEVVQHPWM 512
>UniRef50_Q96NX5 Cluster: Calcium/calmodulin-dependent protein
kinase type 1G; n=19; Euteleostomi|Rep:
Calcium/calmodulin-dependent protein kinase type 1G -
Homo sapiens (Human)
Length = 476
Score = 148 bits (358), Expect = 5e-34
Identities = 90/277 (32%), Positives = 143/277 (51%), Gaps = 16/277 (5%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP 69
++ T + K + + +G GA+++V+L K+ A K I+ + A +D L
Sbjct: 14 KQTTNIRKTFIFMEVLGSGAFSEVFLV----KQRLTGKLFALKCIKKSPAFRD---SSLE 66
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
EI VL ++ H +++ + I++ T YY+ M+ G+L IL+ G +E A + +Q
Sbjct: 67 NEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQ 126
Query: 130 LALGLQYLHELEIAHRDIKCENVL-LT--ANFNVKLSDFGFSRFCVESDNQPVLSETYCG 186
+ ++YLHE I HRD+K EN+L LT N + ++DFG S+ Q + T CG
Sbjct: 127 VLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKM-----EQNGIMSTACG 181
Query: 187 SMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRS 246
+ Y APE+L KPY K D WS+GV+ +++L PF + KL+E+ Y F S
Sbjct: 182 TPGYVAPEVLAQKPY-SKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFES 240
Query: 247 RVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+S K + HLLE DP R++ L WI
Sbjct: 241 PFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWI 277
Score = 130 bits (313), Expect = 2e-28
Identities = 80/239 (33%), Positives = 129/239 (53%), Gaps = 12/239 (5%)
Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+ A K I S A RD L EI +L K+ H ++V I++ Y++ M+ + G+
Sbjct: 48 LFALKCIKKSPAFRD---SSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGE 104
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVL-LTANQNVK--LSD 468
L + +L+RG E A + +Q+ A++Y+HE I HRD+K EN+L LT +N K ++D
Sbjct: 105 LFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITD 164
Query: 469 FGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMP 528
FG ++M + N I S T CG+ Y APE+L PY K D WS+G++ Y++L P
Sbjct: 165 FGLSKM----EQNGIMS-TACGTPGYVAPEVLAQKPY-SKAVDCWSIGVITYILLCGYPP 218
Query: 529 FEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
F ++ +L + ++F S + D IS++ K I +LE + R ++ WI
Sbjct: 219 FYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWI 277
>UniRef50_UPI00015B507B Cluster: PREDICTED: similar to cell cycle
checkpoint kinase 2; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to cell cycle checkpoint kinase 2 -
Nasonia vitripennis
Length = 491
Score = 147 bits (357), Expect = 7e-34
Identities = 98/287 (34%), Positives = 150/287 (52%), Gaps = 18/287 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAP----KDFV--VKFLPREI 72
Y +++ +G GA +V L + E K A KII K K+ V K + E+
Sbjct: 175 YAVSRTLGAGACGEVKLCFSKTGEAGKK--FAMKIISKMKVGTSGHKNPVNDEKSIMNEV 232
Query: 73 DVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLAL 132
D+ RL HP +I + F + YI + E G+L I KN +SE+ A+ Q+ L
Sbjct: 233 DICKRLKHPCIIKIEEFFNSPSMVYIILELMEGGELFERIKKNNGLSESNAKFIFYQVVL 292
Query: 133 GLQYLHELEIAHRDIKCENVLLTANFN---VKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
+ YLH+ I HRD+K EN+LLT + + VK+SDFG S+F D+Q ++ +T+CG+
Sbjct: 293 AVNYLHQNGITHRDLKPENILLTGHEDETIVKVSDFGLSKFV---DSQTMM-KTFCGTPM 348
Query: 190 YAAPEILR--GKPYCPKPTDLWSLGVVLFVMLNKSMPFD-DTRMRKLYEQQMGKKYRFRS 246
Y APEIL+ GK D+WSLGV+L+ L+ +PF + LY+Q + KY F
Sbjct: 349 YVAPEILKTGGKGAYTSQVDVWSLGVILYCCLSGLVPFKIHDKTMSLYDQILSGKYHFNC 408
Query: 247 RVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLN 293
+S K +++ ++ DP R + VL W+ + LT +N
Sbjct: 409 SKFFNVSPSAKDLIRRMMTVDPLKRITIQRVLMHPWLRDNEMLTKVN 455
Score = 121 bits (291), Expect = 7e-26
Identities = 72/233 (30%), Positives = 125/233 (53%), Gaps = 13/233 (5%)
Query: 369 KKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQAR 428
+K + E+++ +L HP ++ F +I + ME G+L E + + + E A+
Sbjct: 225 EKSIMNEVDICKRLKHPCIIKIEEFFNSPSMVYIILELMEGGELFERIKKNNGLSESNAK 284
Query: 429 IWTRQLALAIQYMHELEIAHRDIKCENVLLTANQN---VKLSDFGFARMCVDKKLNEIRS 485
Q+ LA+ Y+H+ I HRD+K EN+LLT +++ VK+SDFG ++ VD ++
Sbjct: 285 FIFYQVVLAVNYLHQNGITHRDLKPENILLTGHEDETIVKVSDFGLSKF-VD---SQTMM 340
Query: 486 ETFCGSLSYTAPEILQ--GTPYLPKPTDVWSLGIVVYVMLNRAMPFE--DKHIKQLHQAQ 541
+TFCG+ Y APEIL+ G DVWSLG+++Y L+ +PF+ DK + L+
Sbjct: 341 KTFCGTPMYVAPEILKTGGKGAYTSQVDVWSLGVILYCCLSGLVPFKIHDKTM-SLYDQI 399
Query: 542 INKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLL 594
++ + F +S + K LI M+ + R+ I ++ W+ D+ +L
Sbjct: 400 LSGKYHFNCSKFFNVSPSAKDLIRRMMTVDPLKRITIQRVLMHPWL-RDNEML 451
>UniRef50_A2ERA7 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 350
Score = 147 bits (357), Expect = 7e-34
Identities = 84/274 (30%), Positives = 137/274 (50%), Gaps = 13/274 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
YK+ K +G GA++ V L S + ACKI ++ + RE+ L L
Sbjct: 24 YKIIKIIGTGAFSIVALVTTLSNSQLY----ACKICSRKSLNENNLFYRFEREVRTLQTL 79
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHP+++ ++ + Y+ M Y ++G+L +I+ V E AR +QL + Y+H
Sbjct: 80 NHPNIVRLYDVVYEDNLIYLIMEYCQHGELFQFIIDQQRVPEFLARNIFKQLLDAIAYIH 139
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+AHRDIK EN+LL A N K++DFG C N+ L ET CGS YA PE++
Sbjct: 140 SKSVAHRDIKPENILLDAENNAKIADFG---LCHPITNK--LLETPCGSPFYAPPEVIAN 194
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y K +D+WSLGVVLF M+ S+P+ +LY Q + + ++ C+
Sbjct: 195 EQYDGKASDVWSLGVVLFTMVTGSLPWRQANQTQLYLQIQNADF----VIPGFVTPNCRD 250
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTL 292
+++ + +P R +++ W + + L
Sbjct: 251 IIQRCMSHNPSERPMPMDLMMHPWFEEQNEMAQL 284
Score = 130 bits (315), Expect = 9e-29
Identities = 72/244 (29%), Positives = 122/244 (50%), Gaps = 9/244 (3%)
Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+ ACK+ + + + RE+ L L+HP++V + + ++ M Y + G+
Sbjct: 49 LYACKICSRKSLNENNLFYRFEREVRTLQTLNHPNIVRLYDVVYEDNLIYLIMEYCQHGE 108
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
L +F++ + V E AR +QL AI Y+H +AHRDIK EN+LL A N K++DFG
Sbjct: 109 LFQFIIDQQRVPEFLARNIFKQLLDAIAYIHSKSVAHRDIKPENILLDAENNAKIADFGL 168
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+K L ET CGS Y PE++ Y K +DVWSLG+V++ M+ ++P+
Sbjct: 169 CHPITNKLL-----ETPCGSPFYAPPEVIANEQYDGKASDVWSLGVVLFTMVTGSLPWRQ 223
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDS 591
+ QL+ N ++ ++ NC+ +I + N R D++ W +
Sbjct: 224 ANQTQLYLQIQNADFVIPG----FVTPNCRDIIQRCMSHNPSERPMPMDLMMHPWFEEQN 279
Query: 592 RLLE 595
+ +
Sbjct: 280 EMAQ 283
>UniRef50_A2D7H7 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 405
Score = 147 bits (357), Expect = 7e-34
Identities = 90/273 (32%), Positives = 154/273 (56%), Gaps = 19/273 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAK--APKDFVVKFLPREIDVLV 76
Y+ VGEG++A+V+ ++ + +A K+I AK PK F +F RE+ ++
Sbjct: 12 YQFISKVGEGSFAEVWKGQHIKSQ----LKVAIKVINKAKFKEPKHFT-RF-NREVAIMK 65
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
++ HP + ++ I + + +Y+ M + E +LL YI +G ++E AR + QL ++Y
Sbjct: 66 QIEHPLIAQIYQIMEDENNHYLIMEFAEGENLLQYINADGKLAEPLARQYFIQLISVVEY 125
Query: 137 LH-ELEIAHRDIKCENVLLTANFNVKLSDFGFSR-FCVESDNQPVLSETYCGSMSYAAPE 194
LH E I HRD+K ENVLL N+N++L DFG S F ++ N ET CGS Y PE
Sbjct: 126 LHKEKNIIHRDLKAENVLLDRNYNIRLIDFGLSNSFSLDHLN----LETACGSPGYLPPE 181
Query: 195 ILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSL 254
+++G+ + D+WSLGV+L+ ++ +PF+D ++ K+ + ++ K F R LS
Sbjct: 182 MIKGQTH-TTAADIWSLGVLLYCIVVGHLPFEDPQIPKILD-KIVKTNPFYPRT---LSA 236
Query: 255 ECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDS 287
+ T++K +L DP R + + W ++D+
Sbjct: 237 DLSTLLKRMLNKDPDQRITLDEIKQHPWFSVDA 269
Score = 126 bits (304), Expect = 2e-27
Identities = 73/242 (30%), Positives = 130/242 (53%), Gaps = 13/242 (5%)
Query: 353 LACKVIDTST--APRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERG 410
+A KVI+ + P+ F + RE+ ++ ++ HP + + I + +++ M + E
Sbjct: 38 VAIKVINKAKFKEPKHFTR--FNREVAIMKQIEHPLIAQIYQIMEDENNHYLIMEFAEGE 95
Query: 411 DLLEFVLQRGAVQEDQARIWTRQLALAIQYMH-ELEIAHRDIKCENVLLTANQNVKLSDF 469
+LL+++ G + E AR + QL ++Y+H E I HRD+K ENVLL N N++L DF
Sbjct: 96 NLLQYINADGKLAEPLARQYFIQLISVVEYLHKEKNIIHRDLKAENVLLDRNYNIRLIDF 155
Query: 470 GFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF 529
G + L+ + ET CGS Y PE+++G + D+WSLG+++Y ++ +PF
Sbjct: 156 GLSN---SFSLDHLNLETACGSPGYLPPEMIKGQTH-TTAADIWSLGVLLYCIVVGHLPF 211
Query: 530 EDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAM 589
ED I ++ ++K K Y T+S + L+ ML + R+ + +I W ++
Sbjct: 212 EDPQIPKI----LDKIVKTNPFYPRTLSADLSTLLKRMLNKDPDQRITLDEIKQHPWFSV 267
Query: 590 DS 591
D+
Sbjct: 268 DA 269
>UniRef50_Q6CJD2 Cluster: Similar to sp|P13186 Saccharomyces
cerevisiae YLR096w KIN2 ser/thr protein kinase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P13186
Saccharomyces cerevisiae YLR096w KIN2 ser/thr protein
kinase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 1104
Score = 147 bits (357), Expect = 7e-34
Identities = 75/214 (35%), Positives = 118/214 (55%), Gaps = 8/214 (3%)
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
RE + L HPH+ + + +Y+ Y G LL YI+++G + E AR + R
Sbjct: 171 REASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLRERHARKFVRG 230
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
+A LQYLH I HRD+K EN++++ + +K+ DFG S DN+ L T+CGS+
Sbjct: 231 IASALQYLHLNNIVHRDLKIENIMISTSGEIKIIDFGLSNL---YDNKKQL-HTFCGSLY 286
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
+AAPE+L+ PY D+WS GVV++V++ +PFDD L+E+ K +
Sbjct: 287 FAAPELLKANPYIGPEVDIWSFGVVIYVLVCGKVPFDDENASVLHEKIKKGKVEYPQH-- 344
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
LS+EC +++ +L DP R S V + +W+
Sbjct: 345 --LSIECISLLSKMLVVDPLKRASLKQVCNHQWM 376
Score = 144 bits (350), Expect = 5e-33
Identities = 69/214 (32%), Positives = 121/214 (56%), Gaps = 8/214 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE + L HPH+ + +++ Y+ G LL++++Q G+++E AR + R
Sbjct: 171 REASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLRERHARKFVRG 230
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+A A+QY+H I HRD+K EN++++ + +K+ DFG + + +KK + TFCGSL
Sbjct: 231 IASALQYLHLNNIVHRDLKIENIMISTSGEIKIIDFGLSNLYDNKK----QLHTFCGSLY 286
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
+ APE+L+ PY+ D+WS G+V+YV++ +PF+D++ LH+ K K + Y
Sbjct: 287 FAAPELLKANPYIGPEVDIWSFGVVIYVLVCGKVPFDDENASVLHE----KIKKGKVEYP 342
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+S C L+ ML + R + + N +W+
Sbjct: 343 QHLSIECISLLSKMLVVDPLKRASLKQVCNHQWM 376
>UniRef50_Q2U7N6 Cluster: Serine/threonine protein kinase; n=8;
Eurotiomycetidae|Rep: Serine/threonine protein kinase -
Aspergillus oryzae
Length = 798
Score = 147 bits (357), Expect = 7e-34
Identities = 83/268 (30%), Positives = 143/268 (53%), Gaps = 13/268 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+ K +GEG++ KV L + + S + +A KII K +V + REI L L
Sbjct: 71 YQTVKVLGEGSFGKVKLAIH---QPSGRQ-VALKIISRRKLLSRDMVGRVEREIQYLQLL 126
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I ++++ KT + + Y E +L Y++K G ++ +AR + +Q+ ++Y H
Sbjct: 127 RHPHIIKLYTVIATKTDIVMVLEYAER-ELFDYLVKRGRCNDAEARKFFQQIICAVEYCH 185
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+I HRD+K EN+L+ + NVK++DFG S + + +T CGS +YAAPE++ G
Sbjct: 186 RHKIVHRDLKPENLLIDSEKNVKIADFGLSNIMTDGN----FLKTSCGSPNYAAPEVISG 241
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS GV+L+V+L +PFDD + L+++ + ++S
Sbjct: 242 KLYAGPEVDVWSCGVILYVLLVGRLPFDDDYIPALFKKIAAGNFHMPPYISS----GAAR 297
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMD 286
+++ +L+ P R + + W D
Sbjct: 298 LIRSMLQVHPVHRLTIPEIRQDPWFQKD 325
Score = 142 bits (344), Expect = 3e-32
Identities = 82/253 (32%), Positives = 139/253 (54%), Gaps = 12/253 (4%)
Query: 353 LACKVIDT-STAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A K+I RD V + + REI+ L L HPH++ +++ + + + Y ER +
Sbjct: 97 VALKIISRRKLLSRDMVGR-VEREIQYLQLLRHPHIIKLYTVIATKTDIVMVLEYAER-E 154
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
L +++++RG + +AR + +Q+ A++Y H +I HRD+K EN+L+ + +NVK++DFG
Sbjct: 155 LFDYLVKRGRCNDAEARKFFQQIICAVEYCHRHKIVHRDLKPENLLIDSEKNVKIADFGL 214
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+ + D +T CGS +Y APE++ G Y DVWS G+++YV+L +PF+D
Sbjct: 215 SNIMTDGNF----LKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVLLVGRLPFDD 270
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD- 590
+I L + N+ IS RLI ML+ + +RL I +I W D
Sbjct: 271 DYIPALFKKIAAGNFHMP----PYISSGAARLIRSMLQVHPVHRLTIPEIRQDPWFQKDL 326
Query: 591 SRLLEWTPQETLA 603
+ L+ P+E +A
Sbjct: 327 PKYLQPPPEEFIA 339
>UniRef50_UPI00006CFC37 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 419
Score = 147 bits (356), Expect = 9e-34
Identities = 73/224 (32%), Positives = 128/224 (57%), Gaps = 4/224 (1%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L + +G+G++A V +S+ K A KII+ K +D ++ L +EI +L+
Sbjct: 8 YELGQILGQGSFAIVREVTHSTT----KQQFAMKIIDKDKVQRDDSIESLKKEISILMMA 63
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+H +++ + + +TK Y+ + Y G+L I G +SE++ R + RQ+ + Y
Sbjct: 64 DHQNIVKLVEVLASRTKIYLVLEYIRGGELWDLIKDRGQISEDEMRKYFRQIIKAIHYCK 123
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ IAHRD+K EN+LL + +K+SDFG S + + L T CG+++Y APE+++
Sbjct: 124 KKNIAHRDLKPENILLDQHGCIKVSDFGLSSLYQDPNQIQNLLHTTCGTINYLAPEVIQN 183
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKY 242
Y D+WSLGV+LF ++ +PF+D + KL E+ + +Y
Sbjct: 184 MGYDGHMADIWSLGVILFFTISGRLPFEDENVAKLLEKIVSVEY 227
Score = 134 bits (325), Expect = 5e-30
Identities = 62/184 (33%), Positives = 107/184 (58%)
Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLL 413
A K+ID RD + L +EI +L+ H ++V + R K ++ + Y+ G+L
Sbjct: 35 AMKIIDKDKVQRDDSIESLKKEISILMMADHQNIVKLVEVLASRTKIYLVLEYIRGGELW 94
Query: 414 EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFAR 473
+ + RG + ED+ R + RQ+ AI Y + IAHRD+K EN+LL + +K+SDFG +
Sbjct: 95 DLIKDRGQISEDEMRKYFRQIIKAIHYCKKKNIAHRDLKPENILLDQHGCIKVSDFGLSS 154
Query: 474 MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKH 533
+ D + T CG+++Y APE++Q Y D+WSLG++++ ++ +PFED++
Sbjct: 155 LYQDPNQIQNLLHTTCGTINYLAPEVIQNMGYDGHMADIWSLGVILFFTISGRLPFEDEN 214
Query: 534 IKQL 537
+ +L
Sbjct: 215 VAKL 218
>UniRef50_Q54VI1 Cluster: Putative uncharacterized protein fhkE;
n=1; Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein fhkE - Dictyostelium discoideum
AX4
Length = 712
Score = 147 bits (356), Expect = 9e-34
Identities = 98/298 (32%), Positives = 158/298 (53%), Gaps = 18/298 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVK--FLPREIDVLV 76
Y + + +G+G +A V L + E + A KI++ K + + L E+++L
Sbjct: 145 YFIGEMLGQGNFATVKL----AVERTTGVKYAVKIVDKKKYFMNSSARKDSLMDEVNILR 200
Query: 77 RLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQY 136
L+HP++I + +F+ + + + E G+LL+ I+ N +E++A+ RQ+ G+ Y
Sbjct: 201 GLSHPNIIQIIEVFENEKVLSLILELVECGELLNDIVSNLFYTEDKAKTLFRQIVDGVLY 260
Query: 137 LHELEIAHRDIKCENVLLT-ANFN----VKLSDFGFSRFCVESDNQPVLSETYCGSMSYA 191
LH IAHRD+K EN+LL NFN +KL+DFG SR SD +T CG+ Y
Sbjct: 261 LHNKGIAHRDLKPENILLKHKNFNQNDAIKLTDFGLSR--TVSDGS--FMKTMCGTPQYL 316
Query: 192 APEILR---GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
APEIL G D WS+G +L++ML PFDD+R ++EQ K+ F
Sbjct: 317 APEILTSSGGHNGYGLEVDCWSMGAILYIMLCGYPPFDDSREVSIFEQIRNAKFEFDPED 376
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKED 306
S +S E K ++K LL DP R++ N++ W + +L+TL + K+A+ +
Sbjct: 377 WSSVSEEAKDLIKRLLCVDPHKRYTCNNIIQHPWFNPNVKLSTLLEEDERLRKKAEAE 434
Score = 119 bits (287), Expect = 2e-25
Identities = 87/296 (29%), Positives = 140/296 (47%), Gaps = 19/296 (6%)
Query: 369 KKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQAR 428
K L E+ +L LSHP+++ +F+ + + +E G+LL ++ ED+A+
Sbjct: 189 KDSLMDEVNILRGLSHPNIIQIIEVFENEKVLSLILELVECGELLNDIVSNLFYTEDKAK 248
Query: 429 IWTRQLALAIQYMHELEIAHRDIKCENVLL---TANQN--VKLSDFGFARMCVDKKLNEI 483
RQ+ + Y+H IAHRD+K EN+LL NQN +KL+DFG +R D
Sbjct: 249 TLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQNDAIKLTDFGLSRTVSDGSF--- 305
Query: 484 RSETFCGSLSYTAPEILQ---GTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQA 540
+T CG+ Y APEIL G D WS+G ++Y+ML PF+D + +
Sbjct: 306 -MKTMCGTPQYLAPEILTSSGGHNGYGLEVDCWSMGAILYIMLCGYPPFDDSREVSIFEQ 364
Query: 541 QINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLLEWTPQE 600
N ++F ++S+ K LI +L + R +I+ W + +L ++
Sbjct: 365 IRNAKFEFDPEDWSSVSEEAKDLIKRLLCVDPHKRYTCNNIIQHPWFNPNVKLSTLLEED 424
Query: 601 TLAYKKAREE----KNKLHKTVETVELPGSSKTEHKVCLPDSLVENNLDGAASTSS 652
KKA E N +K+ + ++ G K+E C + NN G+ S SS
Sbjct: 425 ERLRKKAEAEVEANNNNTNKS-NSPKMLGKRKSEDGNCSDSN--NNNNSGSKSLSS 477
>UniRef50_Q22S16 Cluster: Protein kinase domain containing protein;
n=5; Oligohymenophorea|Rep: Protein kinase domain
containing protein - Tetrahymena thermophila SB210
Length = 384
Score = 147 bits (356), Expect = 9e-34
Identities = 88/272 (32%), Positives = 152/272 (55%), Gaps = 14/272 (5%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
+ + +K K +GEG++A V+ + KE++ + +A K+I+ A D + L E ++
Sbjct: 78 IKEDFKFDKVLGEGSFAVVH--KCIRKENNEE--VAVKVIDKANLEHDDQLA-LETECEI 132
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
+ ++HP+++ ++ K+K+Y+ M G+L I++ SE +A + + +
Sbjct: 133 MANIDHPNIVKCTCVYDEKSKFYMVMELMTGGELFDRIVEKEFYSEKEACDVIKPIVDAI 192
Query: 135 QYLHELEIAHRDIKCENVLLTA---NFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYA 191
Y H++ IAHRD+K EN+L T+ + +K+SDFG ++ V SD L T CG+ SY
Sbjct: 193 NYCHKMGIAHRDLKPENLLYTSPDPDATIKISDFGLAK--VISDE---LMTTACGTPSYI 247
Query: 192 APEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASI 251
APEIL GK Y D WS+GV+L+V+L PF + KL+ ++ F S
Sbjct: 248 APEILEGKGY-TFAVDYWSIGVILYVLLCGFPPFYEDTNEKLFAMIKKGQFEFPSPQWDP 306
Query: 252 LSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+S + K ++K+LL+ DP R++A +L+ WI
Sbjct: 307 ISNQAKDLIKNLLKVDPKQRYNAEQILNHAWI 338
Score = 128 bits (308), Expect = 6e-28
Identities = 79/239 (33%), Positives = 132/239 (55%), Gaps = 12/239 (5%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KVID + D + L E E++ + HP++V ++ + K+++ M M G+L
Sbjct: 108 VAVKVIDKANLEHDD-QLALETECEIMANIDHPNIVKCTCVYDEKSKFYMVMELMTGGEL 166
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTA---NQNVKLSDF 469
+ ++++ E +A + + AI Y H++ IAHRD+K EN+L T+ + +K+SDF
Sbjct: 167 FDRIVEKEFYSEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTSPDPDATIKISDF 226
Query: 470 GFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF 529
G A++ D+ + T CG+ SY APEIL+G Y D WS+G+++YV+L PF
Sbjct: 227 GLAKVISDELMT-----TACGTPSYIAPEILEGKGY-TFAVDYWSIGVILYVLLCGFPPF 280
Query: 530 EDKHIKQLHQAQINK-NWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ ++L A I K ++F S D IS+ K LI +L+ + + R I+N WI
Sbjct: 281 YEDTNEKLF-AMIKKGQFEFPSPQWDPISNQAKDLIKNLLKVDPKQRYNAEQILNHAWI 338
>UniRef50_Q22M67 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila SB210
Length = 1713
Score = 147 bits (356), Expect = 9e-34
Identities = 96/267 (35%), Positives = 143/267 (53%), Gaps = 14/267 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + K VG+GAYA V + +K + K +A KI E + + K + REI +L L
Sbjct: 912 YLVGKQVGQGAYATVRVA--LNKIFNKK--VAIKIYEKQRIKEPQRKKSVRREIKLLQML 967
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYI--LKNGCVSENQARVWTRQLALGLQY 136
NH ++I V+ + I M Y L Y+ N ++EN A+ +QL ++Y
Sbjct: 968 NHQNVIKVYDTIETNNHVNIIMEYIPGTSLHGYLKAQPNRRLTENDAKRIFKQLVSSIEY 1027
Query: 137 LHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
+H +I HRDIK EN+LL N N KL DFGFS C+ +D + + +CG+ SY APEI+
Sbjct: 1028 IHSKQICHRDIKLENILLDENNNPKLIDFGFST-CIPNDQK---YKMFCGTPSYMAPEIV 1083
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
+ Y P D+W+LGV+L+ +L + PF ++LY++ K F S LS E
Sbjct: 1084 NKREYTGPPADIWALGVLLYALLCGTFPFKGQTDKELYKKI--TKGDFLS--PDFLSKEA 1139
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ +K +L D LR +AT VL W+
Sbjct: 1140 RDFIKWVLNTDCDLRPTATEVLSHPWL 1166
Score = 118 bits (284), Expect = 5e-25
Identities = 75/238 (31%), Positives = 125/238 (52%), Gaps = 12/238 (5%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ + KK + REI++L L+H +++ + + I M Y+ L
Sbjct: 938 VAIKIYEKQRIKEPQRKKSVRREIKLLQMLNHQNVIKVYDTIETNNHVNIIMEYIPGTSL 997
Query: 413 ---LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDF 469
L+ R + D RI+ +QL +I+Y+H +I HRDIK EN+LL N N KL DF
Sbjct: 998 HGYLKAQPNRRLTENDAKRIF-KQLVSSIEYIHSKQICHRDIKLENILLDENNNPKLIDF 1056
Query: 470 GFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF 529
GF+ C+ N+ + + FCG+ SY APEI+ Y P D+W+LG+++Y +L PF
Sbjct: 1057 GFS-TCIP---NDQKYKMFCGTPSYMAPEIVNKREYTGPPADIWALGVLLYALLCGTFPF 1112
Query: 530 EDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ + K+L++ +I K F S D +S + I +L + R ++++ W+
Sbjct: 1113 KGQTDKELYK-KITKG-DFLSP--DFLSKEARDFIKWVLNTDCDLRPTATEVLSHPWL 1166
>UniRef50_UPI00006CFA8B Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 579
Score = 147 bits (355), Expect = 1e-33
Identities = 88/287 (30%), Positives = 157/287 (54%), Gaps = 19/287 (6%)
Query: 5 KTTPSEENTLLTKGYKLTKFVGEGAYAKVYL-TEYSSKEDSHKSTLACKIIETAKAPKDF 63
KTT S +N + YK+ K +G+G++ KV L T + KE + KS L A A + +
Sbjct: 82 KTTSSRQN--IYDNYKMIKLIGKGSFGKVRLATNVNGKEFAVKSILK------ADAGERY 133
Query: 64 VVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILK----NGCVS 119
+ L RE+D++ +++HP+L+ + + +I M + + +L Y + N +
Sbjct: 134 YL--LRRELDIMKKVDHPNLVKFYETYHDDKYLHIVMEFVQGKELSQYCQERFEVNRKFT 191
Query: 120 ENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLT-ANFNVKLSDFGFSRFCVESDNQP 178
E++ R+L L ++H L I HRDIK EN+++ +N +VK+ DFG SR S +Q
Sbjct: 192 ESEVAFIVRKLLSALSHMHNLGIIHRDIKLENIMINESNLDVKILDFGLSRDF--SQSQA 249
Query: 179 VLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQM 238
+ ++ G+ Y APE++ +PY K +D WS+GV+++ +++ S PF+ + +++L++
Sbjct: 250 SILQSIVGTPLYVAPEVINEQPYDQK-SDSWSMGVLMYYLISGSHPFEASNIKELFKNIC 308
Query: 239 GKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAM 285
+ FRS S +S K ++ L DP R S L S+W ++
Sbjct: 309 SANFNFRSSAWSGISKSAKVLITQFLNLDPKSRISCEEALQSDWFSV 355
Score = 120 bits (288), Expect = 2e-25
Identities = 68/223 (30%), Positives = 125/223 (56%), Gaps = 8/223 (3%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQ----EDQA 427
L RE++++ K+ HP+LV + + I M +++ +L ++ +R V E +
Sbjct: 136 LRRELDIMKKVDHPNLVKFYETYHDDKYLHIVMEFVQGKELSQYCQERFEVNRKFTESEV 195
Query: 428 RIWTRQLALAIQYMHELEIAHRDIKCENVLLT-ANQNVKLSDFGFARMCVDKKLNEIRSE 486
R+L A+ +MH L I HRDIK EN+++ +N +VK+ DFG +R + + ++S
Sbjct: 196 AFIVRKLLSALSHMHNLGIIHRDIKLENIMINESNLDVKILDFGLSRDFSQSQASILQS- 254
Query: 487 TFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNW 546
G+ Y APE++ PY K +D WS+G+++Y +++ + PFE +IK+L + + N+
Sbjct: 255 -IVGTPLYVAPEVINEQPYDQK-SDSWSMGVLMYYLISGSHPFEASNIKELFKNICSANF 312
Query: 547 KFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAM 589
FRS IS + K LI L + ++R+ + + S+W ++
Sbjct: 313 NFRSSAWSGISKSAKVLITQFLNLDPKSRISCEEALQSDWFSV 355
>UniRef50_UPI0000548690 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 731
Score = 147 bits (355), Expect = 1e-33
Identities = 88/269 (32%), Positives = 150/269 (55%), Gaps = 13/269 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKD-FVVKFLPREIDVLVR 77
Y + K + +G++AKV L S + +A K+I+ KA +D +V+K + RE +
Sbjct: 47 YLVGKMINKGSFAKVMLGMNISTGEK----VAIKVIDKKKARQDSYVLKNMKREPRIHQL 102
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
+ HP+++ + + + YY+ M GDL+ I + + E + R +TRQ+ +++L
Sbjct: 103 IRHPNIVLLLETLETENCYYMAMELCGGGDLMDRICERKRLDEREVRRFTRQILSAVEHL 162
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPV-LSETYCGSMSYAAPEIL 196
H I HRD+K EN LL + N+K+ DFG S ++ D+ V L T CGS +YAAPE+L
Sbjct: 163 HRHGIVHRDLKIENFLLDEHNNIKIVDFGLSN-TLKGDSLSVDLLNTQCGSPAYAAPELL 221
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPF--DDTRMRKLYEQQMGKKYRFRSRVASILSL 254
K Y PK D+WS+GV +F ML ++PF + +++L+++ + + S + S +S
Sbjct: 222 AHKKYGPK-VDVWSVGVSMFAMLTGTLPFTVEPFNIKQLHQKMVNGEI---SPIPSDISK 277
Query: 255 ECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
V LLEP+P R + ++ +W+
Sbjct: 278 AAVEFVLSLLEPEPAKRPTVKAAMEDKWL 306
Score = 134 bits (324), Expect = 7e-30
Identities = 94/307 (30%), Positives = 146/307 (47%), Gaps = 11/307 (3%)
Query: 284 AMDSRLTTLNAVEAAALKRAKEDRRKLSDVHKHPPKRQGDILEGPTRESAFRVYLAEYRN 343
++D +T +E A + R L H KR G L G + N
Sbjct: 8 SLDGSMTDSGELEQPASPCLGKVPRDLLQNFPHT-KRVGSYLVGKMINKGSFAKVMLGMN 66
Query: 344 ASKNDKLSILACKVIDTSTAPRD-FVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFI 402
S +K++I KVID A +D +V K + RE + + HP++V + Y++
Sbjct: 67 ISTGEKVAI---KVIDKKKARQDSYVLKNMKREPRIHQLIRHPNIVLLLETLETENCYYM 123
Query: 403 FMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQ 462
M GDL++ + +R + E + R +TRQ+ A++++H I HRD+K EN LL +
Sbjct: 124 AMELCGGGDLMDRICERKRLDEREVRRFTRQILSAVEHLHRHGIVHRDLKIENFLLDEHN 183
Query: 463 NVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVM 522
N+K+ DFG + L+ T CGS +Y APE+L Y PK DVWS+G+ ++ M
Sbjct: 184 NIKIVDFGLSNTLKGDSLSVDLLNTQCGSPAYAAPELLAHKKYGPK-VDVWSVGVSMFAM 242
Query: 523 LNRAMPF--EDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYD 580
L +PF E +IKQLHQ +N S IS + +LEP R +
Sbjct: 243 LTGTLPFTVEPFNIKQLHQKMVNGE---ISPIPSDISKAAVEFVLSLLEPEPAKRPTVKA 299
Query: 581 IVNSEWI 587
+ +W+
Sbjct: 300 AMEDKWL 306
>UniRef50_A2DI34 Cluster: CAMK family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 498
Score = 147 bits (355), Expect = 1e-33
Identities = 76/216 (35%), Positives = 131/216 (60%), Gaps = 10/216 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKF-LPREIDVLVR 77
Y + +GEG KV L + +D++++ +A KII + K ++ + REI ++
Sbjct: 16 YIPVRTLGEGTTGKVKL---AFNKDTNEN-VAIKIIPKSSFEKKAGLETKVQREIALMGL 71
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
+ HP+++ + +F+ Y+ + Y + G+L Y++ + E+QA + RQ+ L L+YL
Sbjct: 72 VKHPNIMRLIDVFESPKHLYLVLEYAQQGELFDYLISRRVLPEDQALDFFRQIILALEYL 131
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H+ I HRD+K EN+LL A+ +K++DFGF+R+ + ++ET CGS YAAPE++
Sbjct: 132 HKHGICHRDLKPENILLDASTRIKIADFGFARWIKTN-----IAETSCGSPHYAAPEVIS 186
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKL 233
GK Y + D+WS+G++LF +L +PFDD +R L
Sbjct: 187 GKAYDGRKADIWSVGIILFALLAGYLPFDDASIRSL 222
Score = 135 bits (326), Expect = 4e-30
Identities = 67/195 (34%), Positives = 118/195 (60%), Gaps = 6/195 (3%)
Query: 344 ASKNDKLSILACKVIDTSTAPRDF-VKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFI 402
A D +A K+I S+ + ++ + REI ++ + HP+++ +F+ ++
Sbjct: 33 AFNKDTNENVAIKIIPKSSFEKKAGLETKVQREIALMGLVKHPNIMRLIDVFESPKHLYL 92
Query: 403 FMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQ 462
+ Y ++G+L ++++ R + EDQA + RQ+ LA++Y+H+ I HRD+K EN+LL A+
Sbjct: 93 VLEYAQQGELFDYLISRRVLPEDQALDFFRQIILALEYLHKHGICHRDLKPENILLDAST 152
Query: 463 NVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVM 522
+K++DFGFAR K N +ET CGS Y APE++ G Y + D+WS+GI+++ +
Sbjct: 153 RIKIADFGFARWI---KTN--IAETSCGSPHYAAPEVISGKAYDGRKADIWSVGIILFAL 207
Query: 523 LNRAMPFEDKHIKQL 537
L +PF+D I+ L
Sbjct: 208 LAGYLPFDDASIRSL 222
>UniRef50_A7TFG1 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 1123
Score = 147 bits (355), Expect = 1e-33
Identities = 87/270 (32%), Positives = 145/270 (53%), Gaps = 16/270 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP--------R 70
+KL + +G G+ KV L S + K + ++ +V P R
Sbjct: 19 WKLGETLGLGSTGKVQLAYNESTNQQAAIKVISKSVFSSMGNNSSMVSSTPDSLSYGIER 78
Query: 71 EIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQL 130
EI ++ LNHP+++ ++ +++ Y+ + Y E G+L + +++ G + EN+A + RQ+
Sbjct: 79 EIIIMKLLNHPNVLRLYDVWETNNNLYMVLEYAEKGELFNLLVEKGPLPENEAIRFFRQI 138
Query: 131 ALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSY 190
+G+ Y H L I HRD+K EN+LL N+K++DFG + +E++++ L ET CGS Y
Sbjct: 139 IIGMSYCHALGIVHRDLKPENILLDHKLNIKIADFGMA--ALETEDK--LLETSCGSPHY 194
Query: 191 AAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFD--DTRMRKLYEQQMGKKYRFRSRV 248
AAPEI+ G PY TD+WS GV+LF +L +PFD D +R L + +K F
Sbjct: 195 AAPEIVSGLPYHGLETDVWSCGVILFALLTGRLPFDEEDGNIRNLLLKV--QKGEFEMPG 252
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVL 278
+S E + ++ +L DP R + +L
Sbjct: 253 DDEISKEAQDLLYKILVVDPEKRIKSREIL 282
Score = 135 bits (326), Expect = 4e-30
Identities = 74/224 (33%), Positives = 130/224 (58%), Gaps = 9/224 (4%)
Query: 361 STAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRG 420
S+ P D + + REI ++ L+HP+++ + +++ ++ + Y E+G+L ++++G
Sbjct: 66 SSTP-DSLSYGIEREIIIMKLLNHPNVLRLYDVWETNNNLYMVLEYAEKGELFNLLVEKG 124
Query: 421 AVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKL 480
+ E++A + RQ+ + + Y H L I HRD+K EN+LL N+K++DFG A + + KL
Sbjct: 125 PLPENEAIRFFRQIIIGMSYCHALGIVHRDLKPENILLDHKLNIKIADFGMAALETEDKL 184
Query: 481 NEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF--EDKHIKQLH 538
ET CGS Y APEI+ G PY TDVWS G++++ +L +PF ED +I+ L
Sbjct: 185 ----LETSCGSPHYAAPEIVSGLPYHGLETDVWSCGVILFALLTGRLPFDEEDGNIRNL- 239
Query: 539 QAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIV 582
++ K +F D IS + L+ +L + + R+K +I+
Sbjct: 240 LLKVQKG-EFEMPGDDEISKEAQDLLYKILVVDPEKRIKSREIL 282
>UniRef50_UPI00015A5AA6 Cluster: UPI00015A5AA6 related cluster; n=1;
Danio rerio|Rep: UPI00015A5AA6 UniRef100 entry - Danio
rerio
Length = 1024
Score = 146 bits (354), Expect = 2e-33
Identities = 73/239 (30%), Positives = 135/239 (56%), Gaps = 11/239 (4%)
Query: 47 STLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLIHVHS-IFQRKTKYYIFMRYTEN 105
S +A KI++ + + + K RE+ ++ L HPH+I ++ + + + Y+ Y
Sbjct: 1 SQVAIKIVDKTQLDDENLKKIF-REVQIMKMLRHPHIIRLYQQVMETERMIYLVTEYASG 59
Query: 106 GDLLS-YILKNGCVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSD 164
G++ + +++ +G ++E AR +Q+ + + H I HRD+K EN+LL N N+K++D
Sbjct: 60 GEIFADHLVAHGRMAEKDARRKFKQIVAAVYFCHCRSIVHRDLKAENLLLDHNLNIKIAD 119
Query: 165 FGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMP 224
FGFS L +T+CGS YAAPE+ GK Y D+WSLGVVL+V++ ++P
Sbjct: 120 FGFSNLFSRGQ----LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALP 175
Query: 225 FDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
FD + ++ L + + K+ R+ + +C+ +++H+L +P R S + ++W+
Sbjct: 176 FDGSTLQNLRARVLSGKF----RIPFFMFSDCEYLIRHMLILEPSRRLSMEQICKNKWM 230
Score = 129 bits (311), Expect = 3e-28
Identities = 73/239 (30%), Positives = 133/239 (55%), Gaps = 11/239 (4%)
Query: 351 SILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHS-IFQRRYKYFIFMRYMER 409
S +A K++D + + +KK RE++++ L HPH++ + + + ++ Y
Sbjct: 1 SQVAIKIVDKTQLDDENLKKIF-REVQIMKMLRHPHIIRLYQQVMETERMIYLVTEYASG 59
Query: 410 GDLL-EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSD 468
G++ + ++ G + E AR +Q+ A+ + H I HRD+K EN+LL N N+K++D
Sbjct: 60 GEIFADHLVAHGRMAEKDARRKFKQIVAAVYFCHCRSIVHRDLKAENLLLDHNLNIKIAD 119
Query: 469 FGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMP 528
FGF+ + +L +T+CGS Y APE+ +G Y D+WSLG+V+YV++ A+P
Sbjct: 120 FGFSNLFSRGQL----LKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALP 175
Query: 529 FEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
F+ ++ L +A++ + KFR + + +C+ LI ML RL + I ++W+
Sbjct: 176 FDGSTLQNL-RARV-LSGKFRIPFF--MFSDCEYLIRHMLILEPSRRLSMEQICKNKWM 230
>UniRef50_A2DRR6 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 375
Score = 146 bits (354), Expect = 2e-33
Identities = 85/274 (31%), Positives = 137/274 (50%), Gaps = 12/274 (4%)
Query: 9 SEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68
SEE YK+ +G GA+A VY + + A K + + +
Sbjct: 2 SEEIPEYIHHYKINGVIGSGAFATVY----KAYNPELRRLFAIKCFKKSNLKNSKEEETF 57
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTR 128
REID + ++HP L+ +H+IF+ + +Y+ + Y G+L YILK + E+ A + +
Sbjct: 58 QREIDTMAYMDHPGLVKLHNIFEDENNFYLVLDYCAGGELFDYILKKKRLDEHTAALVFK 117
Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
Q+ + Y H IAHRD+K EN+L+ V +SDFG + ES L T+ GS
Sbjct: 118 QIVSAISYCHSFGIAHRDLKPENILIDKFPKVMISDFGLCGYLKES----TLMSTFVGSP 173
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
Y APE L+ + Y + +D+WSLGV+LF M+ P+ + +Q + +
Sbjct: 174 IYTAPECLQNQEYDGRLSDIWSLGVILFGMVTGEHPWKTNNTAIMLKQIYNADFTY---- 229
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
S LS + K ++ +L+ DP R S N+L ++W
Sbjct: 230 PSYLSNDVKELIGSMLKVDPLERKSLENILKNDW 263
Score = 129 bits (311), Expect = 3e-28
Identities = 72/235 (30%), Positives = 127/235 (54%), Gaps = 8/235 (3%)
Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+ A K S ++ REI+ + + HP LV H+IF+ +++ + Y G+
Sbjct: 37 LFAIKCFKKSNLKNSKEEETFQREIDTMAYMDHPGLVKLHNIFEDENNFYLVLDYCAGGE 96
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
L +++L++ + E A + +Q+ AI Y H IAHRD+K EN+L+ V +SDFG
Sbjct: 97 LFDYILKKKRLDEHTAALVFKQIVSAISYCHSFGIAHRDLKPENILIDKFPKVMISDFG- 155
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+C K + + S TF GS YTAPE LQ Y + +D+WSLG++++ M+ P++
Sbjct: 156 --LCGYLKESTLMS-TFVGSPIYTAPECLQNQEYDGRLSDIWSLGVILFGMVTGEHPWKT 212
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+ + + N ++ + S +S++ K LIG ML+ + R + +I+ ++W
Sbjct: 213 NNTAIMLKQIYNADFTYPS----YLSNDVKELIGSMLKVDPLERKSLENILKNDW 263
>UniRef50_Q9UAY1 Cluster: Putative uncharacterized protein; n=5;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 726
Score = 146 bits (353), Expect = 2e-33
Identities = 73/235 (31%), Positives = 134/235 (57%), Gaps = 6/235 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+ID D + + E++ L LSH ++ + + K+FI M Y G++
Sbjct: 37 VAIKIIDKKQLGHDLPR--VQTEMDALRNLSHQNICRLYHYIETEDKFFIVMEYCSGGEM 94
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++++ ++E +AR + RQL AI ++H AHRD+K EN+LLT + ++KL DFG
Sbjct: 95 FDYIVRKERLEESEARHFFRQLVSAIAFVHSQGYAHRDLKPENLLLTEDLHLKLIDFGLC 154
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
++++ +T CGS +Y APE++QG Y DVWS+GI++Y +L A+PFED
Sbjct: 155 AKTEKGRIDKHNLDTCCGSPAYAAPELIQGLQYKGNEADVWSMGILLYTLLVGALPFEDD 214
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
++ Q+ +I + ++ +S K+L+ ML+ + R+ + ++ +W+
Sbjct: 215 NM-QIMYKKIQSGCFYEPEFLSPLS---KQLLRAMLQVVPERRISVKKLLEHDWL 265
Score = 137 bits (332), Expect = 8e-31
Identities = 79/266 (29%), Positives = 142/266 (53%), Gaps = 12/266 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + +G G + KV L + +A KII+ + D + + E+D L L
Sbjct: 11 YAVHDELGSGGFGKVRLATHLLTNQK----VAIKIIDKKQLGHD--LPRVQTEMDALRNL 64
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+H ++ ++ + + K++I M Y G++ YI++ + E++AR + RQL + ++H
Sbjct: 65 SHQNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERLEESEARHFFRQLVSAIAFVH 124
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
AHRD+K EN+LLT + ++KL DFG + +T CGS +YAAPE+++G
Sbjct: 125 SQGYAHRDLKPENLLLTEDLHLKLIDFGLCAKTEKGRIDKHNLDTCCGSPAYAAPELIQG 184
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ-QMGKKYRFRSRVASILSLECK 257
Y D+WS+G++L+ +L ++PF+D M+ +Y++ Q G Y LS K
Sbjct: 185 LQYKGNEADVWSMGILLYTLLVGALPFEDDNMQIMYKKIQSGCFYE-----PEFLSPLSK 239
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWI 283
+++ +L+ P R S +L+ +W+
Sbjct: 240 QLLRAMLQVVPERRISVKKLLEHDWL 265
>UniRef50_Q7R4G4 Cluster: GLP_49_88961_90850; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_49_88961_90850 - Giardia lamblia
ATCC 50803
Length = 629
Score = 146 bits (353), Expect = 2e-33
Identities = 78/219 (35%), Positives = 123/219 (56%), Gaps = 9/219 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y L + +G G + KV + + T+A KI+ +K + + + REI ++
Sbjct: 10 YLLGRQLGTGTFGKVRVATHIPTN----CTVAIKILSKSKITQMNMWSKVEREIMIMKMA 65
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HPH+I+++ + R+ Y+ M Y E G+L SYI+K+ + AR + +Q+ L YLH
Sbjct: 66 RHPHIINLYEVIYREDDIYLVMEYAEGGELFSYIVKHKRLDSTTARKFFQQIISALSYLH 125
Query: 139 -ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
++ + HRD+K EN+LLT N +KLSDFG S E + +T CGS +YA+PE++
Sbjct: 126 IKVSVTHRDLKPENILLTKNKLIKLSDFGLSNVMSEGE----FLKTSCGSPNYASPEVVA 181
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ 236
G Y TD+WS G VL+ +L +PFDD M L+ +
Sbjct: 182 GTLYIGPATDIWSAGCVLYTLLVGRLPFDDHYMPALFRK 220
Score = 126 bits (303), Expect = 2e-27
Identities = 59/186 (31%), Positives = 109/186 (58%), Gaps = 5/186 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++ S + + + REI ++ HPH+++ + + R ++ M Y E G+L
Sbjct: 36 VAIKILSKSKITQMNMWSKVEREIMIMKMARHPHIINLYEVIYREDDIYLVMEYAEGGEL 95
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMH-ELEIAHRDIKCENVLLTANQNVKLSDFGF 471
++++ + AR + +Q+ A+ Y+H ++ + HRD+K EN+LLT N+ +KLSDFG
Sbjct: 96 FSYIVKHKRLDSTTARKFFQQIISALSYLHIKVSVTHRDLKPENILLTKNKLIKLSDFGL 155
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+ + + + +T CGS +Y +PE++ GT Y+ TD+WS G V+Y +L +PF+D
Sbjct: 156 SNVMSEGEF----LKTSCGSPNYASPEVVAGTLYIGPATDIWSAGCVLYTLLVGRLPFDD 211
Query: 532 KHIKQL 537
++ L
Sbjct: 212 HYMPAL 217
>UniRef50_Q54CY9 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 313
Score = 146 bits (353), Expect = 2e-33
Identities = 91/280 (32%), Positives = 144/280 (51%), Gaps = 18/280 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G+GA++ V+L E K A KII+ + K L EI+++ ++
Sbjct: 6 YELHKEIGKGAFSVVFLVT----EKKTKKQWAMKIIDKKSSSK----AALETEIEIMKKV 57
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP+++ +H F+ K Y+ + G L I+ +E +A++ T+QL L YLH
Sbjct: 58 DHPNIVKMHEYFESTDKIYLVVELVTGGPLFDRIVDKKSFTEKEAKLITQQLLQSLVYLH 117
Query: 139 ELEIAHRDIKCENVLL--TANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
+ I HRD+K EN+LL + V LSDFG S+ V D V +T CG+ SY APE+L
Sbjct: 118 SIGIVHRDLKPENLLLKTPTDLTVALSDFGLSKI-VGDD---VFMKTTCGTPSYVAPEVL 173
Query: 197 RGKPYCP----KPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASIL 252
P D+W +GV+ +++L PF +RKL+E + Y F + +
Sbjct: 174 NNISNSPTAYSDAVDMWGVGVITYILLCGFPPFYSEDIRKLFESILSASYDFPNDYWGNV 233
Query: 253 SLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTL 292
S E K + LL +P R+SA L+ WI +++ L
Sbjct: 234 SKEAKHFINCLLTVEPTKRYSAKQALEHPWIIENNQTQPL 273
Score = 124 bits (299), Expect = 8e-27
Identities = 75/269 (27%), Positives = 135/269 (50%), Gaps = 17/269 (6%)
Query: 354 ACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLL 413
A K+ID ++ K L EIE++ K+ HP++V H F+ K ++ + + G L
Sbjct: 33 AMKIIDKKSSS----KAALETEIEIMKKVDHPNIVKMHEYFESTDKIYLVVELVTGGPLF 88
Query: 414 EFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLL--TANQNVKLSDFGF 471
+ ++ + + E +A++ T+QL ++ Y+H + I HRD+K EN+LL + V LSDFG
Sbjct: 89 DRIVDKKSFTEKEAKLITQQLLQSLVYLHSIGIVHRDLKPENLLLKTPTDLTVALSDFGL 148
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLP----KPTDVWSLGIVVYVMLNRAM 527
+++ D ++ +T CG+ SY APE+L P D+W +G++ Y++L
Sbjct: 149 SKIVGD----DVFMKTTCGTPSYVAPEVLNNISNSPTAYSDAVDMWGVGVITYILLCGFP 204
Query: 528 PFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
PF + I++L ++ ++ ++ F + Y +S K I +L R + WI
Sbjct: 205 PFYSEDIRKLFESILSASYDFPNDYWGNVSKEAKHFINCLLTVEPTKRYSAKQALEHPWI 264
Query: 588 AMDSR---LLEWTPQETLAYKKAREEKNK 613
+++ L W Q R+E K
Sbjct: 265 IENNQTQPLPHWNDQIKKYMVIRRKESQK 293
>UniRef50_A2E194 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 375
Score = 146 bits (353), Expect = 2e-33
Identities = 90/302 (29%), Positives = 162/302 (53%), Gaps = 19/302 (6%)
Query: 12 NTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL--P 69
NT + Y + +G G+++KVYL + + +A K+I + KA D + +
Sbjct: 2 NTQINDNYLVKYKIGAGSFSKVYLAVHRKTQIE----VAIKMI-SKKANNDDGKQLIRIQ 56
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
REI+++ + HP + ++ +++ ++ M Y+ NG +L++I G SE+++ V Q
Sbjct: 57 REIEIMKKARHPFITELYEVYENDDFVFLVMEYSPNGTILNHIRDIGAYSEHESAVIFSQ 116
Query: 130 LALGLQYL-HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
L L +++L +AHRD+K EN+L + N+++ DFG S S N L T CGS+
Sbjct: 117 LILAMKHLQRSCNVAHRDLKAENILFDIHQNIRVIDFGLS----NSPNDDNLMNTQCGSL 172
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
YA+PE++ GK Y +D+WS GVVLF M +PF+D+ M +L ++ + K+ + +
Sbjct: 173 DYASPEMILGKQYI-YSSDIWSAGVVLFAMTTGHLPFEDSNMSRLAQRIIFKEIDYPTN- 230
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI--AMDSRLTTLNAVEAAALKRAKED 306
LS + ++K +L DP R + ++ W+ A+ T+N E +K ++
Sbjct: 231 ---LSRDLLDLLKKMLVKDPNQRINLDEIMRHPWLHTAIQYVNETINKFEYDNIKITEQL 287
Query: 307 RR 308
R+
Sbjct: 288 RQ 289
Score = 125 bits (301), Expect = 4e-27
Identities = 72/254 (28%), Positives = 133/254 (52%), Gaps = 14/254 (5%)
Query: 335 RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIF 394
+VYLA +R + +++ K + + ++ + REIE++ K HP + + ++
Sbjct: 22 KVYLAVHRKTQIEVAIKMISKKA--NNDDGKQLIR--IQREIEIMKKARHPFITELYEVY 77
Query: 395 QRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYM-HELEIAHRDIKC 453
+ F+ M Y G +L + GA E ++ + QL LA++++ +AHRD+K
Sbjct: 78 ENDDFVFLVMEYSPNGTILNHIRDIGAYSEHESAVIFSQLILAMKHLQRSCNVAHRDLKA 137
Query: 454 ENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVW 513
EN+L +QN+++ DFG + D L T CGSL Y +PE++ G Y+ +D+W
Sbjct: 138 ENILFDIHQNIRVIDFGLSNSPNDDNL----MNTQCGSLDYASPEMILGKQYI-YSSDIW 192
Query: 514 SLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQ 573
S G+V++ M +PFED ++ +L Q I K + + + D K++ L+ +PN
Sbjct: 193 SAGVVLFAMTTGHLPFEDSNMSRLAQRIIFKEIDYPTNLSRDLLDLLKKM--LVKDPN-- 248
Query: 574 NRLKIYDIVNSEWI 587
R+ + +I+ W+
Sbjct: 249 QRINLDEIMRHPWL 262
>UniRef50_A2DTF0 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 399
Score = 146 bits (353), Expect = 2e-33
Identities = 86/278 (30%), Positives = 142/278 (51%), Gaps = 13/278 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
YK VG+GA++ V L K + ACKI+ A+ + K EI + ++
Sbjct: 15 YKFRGTVGDGAFSVVKLV----KNIENNQYYACKIVPKARLNTIHLEKRFEIEIRIAQQM 70
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP ++ + + + YY+ M + NG+L +I+ +SE++A+ RQ+ LQY+H
Sbjct: 71 HHPGIVELCDLLKDDNNYYVIMEFCPNGELFQFIVDRNNLSEDEAKPLFRQILEALQYVH 130
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
++HRD+K EN+L+ +K+SDFG S F V+S L +T CGS YA+PE + G
Sbjct: 131 SHGVSHRDLKPENLLIDNLGRIKISDFGLSIF-VDSQG---LVKTPCGSPCYASPECISG 186
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y TD+WS GV+L+ ML +P+ +L++Q Y + LS +
Sbjct: 187 QLYDGMTTDVWSAGVILYAMLTGQLPWKKRNQAQLFKQIKSGDY----TIPDELSSDATN 242
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI-AMDSRLTTLNAV 295
++ LL DP R + L W+ D + T+ +
Sbjct: 243 MLTRLLTVDPKARITIEEALQHPWLRGCDQQYPTVRQI 280
Score = 124 bits (300), Expect = 6e-27
Identities = 78/272 (28%), Positives = 139/272 (51%), Gaps = 14/272 (5%)
Query: 317 PPKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREI 376
PP+ G + AF V + +N N ACK++ + ++K EI
Sbjct: 9 PPQIGPYKFRGTVGDGAFSV-VKLVKNIENNQ---YYACKIVPKARLNTIHLEKRFEIEI 64
Query: 377 EMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLAL 436
+ ++ HP +V + + Y++ M + G+L +F++ R + ED+A+ RQ+
Sbjct: 65 RIAQQMHHPGIVELCDLLKDDNNYYVIMEFCPNGELFQFIVDRNNLSEDEAKPLFRQILE 124
Query: 437 AIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTA 496
A+QY+H ++HRD+K EN+L+ +K+SDFG + + VD ++ +T CGS Y +
Sbjct: 125 ALQYVHSHGVSHRDLKPENLLIDNLGRIKISDFGLS-IFVD---SQGLVKTPCGSPCYAS 180
Query: 497 PEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI-DT 555
PE + G Y TDVWS G+++Y ML +P+ K+ +QAQ+ K K I D
Sbjct: 181 PECISGQLYDGMTTDVWSAGVILYAMLTGQLPW-----KKRNQAQLFKQIKSGDYTIPDE 235
Query: 556 ISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+S + ++ +L + + R+ I + + W+
Sbjct: 236 LSSDATNMLTRLLTVDPKARITIEEALQHPWL 267
>UniRef50_Q6BPF2 Cluster: Similar to CA4097|CaGIN4 Candida albicans
CaGIN4 ser/thr protein kinase; n=2;
Saccharomycetaceae|Rep: Similar to CA4097|CaGIN4 Candida
albicans CaGIN4 ser/thr protein kinase - Debaryomyces
hansenii (Yeast) (Torulaspora hansenii)
Length = 1314
Score = 146 bits (353), Expect = 2e-33
Identities = 89/266 (33%), Positives = 137/266 (51%), Gaps = 14/266 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDS------HKSTLACKIIETAKAPKDFVVKFLPREI 72
+KL K +G GA +V L + S KS L I A + + + REI
Sbjct: 29 WKLGKTLGRGATGRVLLATHQSTGQKAAVKVVSKSELNDDEINKKSADEAGLPYGIEREI 88
Query: 73 DVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLAL 132
++ L HP+++ ++ +++ Y+ + Y E G+L +++ G + E +A + RQ+ L
Sbjct: 89 IIMKLLTHPNVLRLYDVWETSKALYLVLEYVEGGELFDLLVERGPLQEVEAIKYFRQIIL 148
Query: 133 GLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAA 192
G Y H L I HRD+K EN+LL + NVKL+DFG + +ES+ + L ET CGS YAA
Sbjct: 149 GTAYCHALGICHRDLKPENLLLDSGLNVKLADFGMA--ALESNGK--LLETSCGSPHYAA 204
Query: 193 PEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASIL 252
PEI+ G Y +D+WS GV+LF +L +PFDD +R L + + L
Sbjct: 205 PEIVSGLKYHGAASDIWSCGVILFALLTGRLPFDDENIRNLLLKVQAGSFEMPCE----L 260
Query: 253 SLECKTVVKHLLEPDPGLRHSATNVL 278
S E ++ +L DP R +L
Sbjct: 261 SPEAVDLIDKMLTVDPMKRIPTERIL 286
Score = 132 bits (319), Expect = 3e-29
Identities = 62/166 (37%), Positives = 105/166 (63%), Gaps = 4/166 (2%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ REI ++ L+HP+++ + +++ ++ + Y+E G+L + +++RG +QE +A +
Sbjct: 84 IEREIIIMKLLTHPNVLRLYDVWETSKALYLVLEYVEGGELFDLLVERGPLQEVEAIKYF 143
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
RQ+ L Y H L I HRD+K EN+LL + NVKL+DFG A + + KL ET CGS
Sbjct: 144 RQIILGTAYCHALGICHRDLKPENLLLDSGLNVKLADFGMAALESNGKL----LETSCGS 199
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQL 537
Y APEI+ G Y +D+WS G++++ +L +PF+D++I+ L
Sbjct: 200 PHYAAPEIVSGLKYHGAASDIWSCGVILFALLTGRLPFDDENIRNL 245
>UniRef50_Q9LDI3 Cluster: CBL-interacting serine/threonine-protein
kinase 24; n=71; Magnoliophyta|Rep: CBL-interacting
serine/threonine-protein kinase 24 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 446
Score = 146 bits (353), Expect = 2e-33
Identities = 80/268 (29%), Positives = 141/268 (52%), Gaps = 11/268 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y++ + +GEG +AKV + D+ +A KI+ + K+ +V + REI ++ +
Sbjct: 11 YEVGRTIGEGTFAKVKFARNTDTGDN----VAIKIMAKSTILKNRMVDQIKREISIMKIV 66
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP+++ ++ + +K YI + + G+L I+ G + E+++R + +QL + + H
Sbjct: 67 RHPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCH 126
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ HRD+K EN+LL N N+K+SDFG S E L T CG+ +Y APE+L G
Sbjct: 127 CKGVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVE---LLRTTCGTPNYVAPEVLSG 183
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y D+WS GV+LFV+L +PF +T + LY + ++ S E K
Sbjct: 184 QGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEF----SCPPWFSAEVKF 239
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMD 286
++ +L+P+P R + W ++
Sbjct: 240 LIHRILDPNPKTRIQIQGIKKDPWFRLN 267
Score = 126 bits (305), Expect = 1e-27
Identities = 73/252 (28%), Positives = 139/252 (55%), Gaps = 7/252 (2%)
Query: 339 AEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRY 398
A+ + A D +A K++ ST ++ + + REI ++ + HP++V + +
Sbjct: 23 AKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPNIVRLYEVLASPS 82
Query: 399 KYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLL 458
K +I + ++ G+L + ++ +G ++E ++R + +QL A+ + H + HRD+K EN+LL
Sbjct: 83 KIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGVYHRDLKPENLLL 142
Query: 459 TANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIV 518
N N+K+SDFG + + + + +R T CG+ +Y APE+L G Y D+WS G++
Sbjct: 143 DTNGNLKVSDFGLSAL-PQEGVELLR--TTCGTPNYVAPEVLSGQGYDGSAADIWSCGVI 199
Query: 519 VYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKI 578
++V+L +PF + + L++ +IN +F S K LI +L+PN + R++I
Sbjct: 200 LFVILAGYLPFSETDLPGLYR-KINAA-EFSCP--PWFSAEVKFLIHRILDPNPKTRIQI 255
Query: 579 YDIVNSEWIAMD 590
I W ++
Sbjct: 256 QGIKKDPWFRLN 267
>UniRef50_Q4E3J2 Cluster: Serine/threonine protein kinase, putative;
n=1; Trypanosoma cruzi|Rep: Serine/threonine protein
kinase, putative - Trypanosoma cruzi
Length = 646
Score = 145 bits (352), Expect = 3e-33
Identities = 82/264 (31%), Positives = 138/264 (52%), Gaps = 12/264 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + + +G+G++ KV + + T+A KI+ K + K + RE+ +L
Sbjct: 24 YAMGETIGKGSFGKVRKGRHLPTGE----TVAIKILNRNKLNNAKMGKRVYREMKILKLF 79
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP++ ++ + T Y+ M Y E G+L YI+K + E+ R +Q+ L+Y H
Sbjct: 80 SHPNICRLYEVITTPTDMYLIMEYVEGGELYDYIVKRRMLKEDVGRYILQQIVCALEYCH 139
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ HRD+K EN+LL VKL DFG + + DN+ + S CGS +YAAPEIL G
Sbjct: 140 HFLVVHRDLKPENILLGPGLQVKLIDFGLAN--IMKDNEFLASS--CGSPNYAAPEILSG 195
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
K Y D+WS GV+L+ +L +PFD+ + L+ + +Y+ V S +
Sbjct: 196 KLYFGPEVDVWSCGVILYALLCGCLPFDEESIPLLFSKIKKGQYQIPPHV----SHGARE 251
Query: 259 VVKHLLEPDPGLRHSATNVLDSEW 282
+++ +L DP +R + + D+ W
Sbjct: 252 LIEQILVVDPLMRLTIPQIRDNAW 275
Score = 128 bits (310), Expect = 3e-28
Identities = 73/234 (31%), Positives = 126/234 (53%), Gaps = 8/234 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ + + K + RE+++L SHP++ + + ++ M Y+E G+L
Sbjct: 50 VAIKILNRNKLNNAKMGKRVYREMKILKLFSHPNICRLYEVITTPTDMYLIMEYVEGGEL 109
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+++++R ++ED R +Q+ A++Y H + HRD+K EN+LL VKL DFG A
Sbjct: 110 YDYIVKRRMLKEDVGRYILQQIVCALEYCHHFLVVHRDLKPENILLGPGLQVKLIDFGLA 169
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ D NE + + CGS +Y APEIL G Y DVWS G+++Y +L +PF+++
Sbjct: 170 NIMKD---NEFLASS-CGSPNYAAPEILSGKLYFGPEVDVWSCGVILYALLCGCLPFDEE 225
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
I L +K K + + +S + LI +L + RL I I ++ W
Sbjct: 226 SIPLL----FSKIKKGQYQIPPHVSHGARELIEQILVVDPLMRLTIPQIRDNAW 275
>UniRef50_O17879 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 399
Score = 145 bits (352), Expect = 3e-33
Identities = 92/295 (31%), Positives = 155/295 (52%), Gaps = 15/295 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L K +G G ++KV L + K +A KI++ AK K L REI + +
Sbjct: 33 YRLGKELGAGNFSKVKLGVHQLT----KEKVAVKIMDKAKMDAK-AQKLLSREIQAMEEM 87
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHP+++ + + + T+ ++ + Y G+L +Y+ + G ++E A+ Q+ + ++H
Sbjct: 88 NHPNIVKLFEVVETLTRVHLVIEYASGGELYTYVHERGKLTEGDAKPLFAQIVSAVSHMH 147
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRDIK ENV+ ++ VKL DFGFS C+ Q + T+CGS YAAPE+ +
Sbjct: 148 SRNIVHRDIKAENVMFSSPNTVKLVDFGFS--CLVDREQ--MLRTFCGSPPYAAPELFQD 203
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y + D+W+LGV+LF ML PF + + KY+ V S+L+ E
Sbjct: 204 TSYAGELVDVWALGVLLFFMLIGVTPFKAETVPDMKVLITAGKYQIPDYV-SLLATE--- 259
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAMDSRLT-TLNAVEAAALKRAKEDRRKLSD 312
++K +L+ D G R +V W+ D R T + +++A A +E+++ + D
Sbjct: 260 LIKSMLKTDTGQRADIDSVKKHFWM-RDCRFTKSYLSIKATAKIDNEEEKKAIDD 313
Score = 122 bits (294), Expect = 3e-26
Identities = 63/185 (34%), Positives = 105/185 (56%), Gaps = 5/185 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++D + +K L REI+ + +++HP++V + + + + + Y G+L
Sbjct: 59 VAVKIMDKAKMDAK-AQKLLSREIQAMEEMNHPNIVKLFEVVETLTRVHLVIEYASGGEL 117
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+V +RG + E A+ Q+ A+ +MH I HRDIK ENV+ ++ VKL DFGF+
Sbjct: 118 YTYVHERGKLTEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVMFSSPNTVKLVDFGFS 177
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ VD+ E TFCGS Y APE+ Q T Y + DVW+LG++++ ML PF+ +
Sbjct: 178 CL-VDR---EQMLRTFCGSPPYAAPELFQDTSYAGELVDVWALGVLLFFMLIGVTPFKAE 233
Query: 533 HIKQL 537
+ +
Sbjct: 234 TVPDM 238
>UniRef50_A2F3L4 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 388
Score = 145 bits (352), Expect = 3e-33
Identities = 85/268 (31%), Positives = 150/268 (55%), Gaps = 15/268 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR-EIDVLVR 77
Y + +G G +A+V+L ++ + +A K+I + + L R EID++ +
Sbjct: 9 YSVQFNIGSGTFAQVFLAIHNKTG----TKVAIKVISKLNCIDNERNQLLMRREIDIMKK 64
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
L HP + ++ + + + YI M + +NG LL I G + E A + QL + ++YL
Sbjct: 65 LKHPFVCDLYEVVETEKNVYIVMEFAQNGTLLETIKSRGSLGEEDASIIFAQLLIVMKYL 124
Query: 138 H-ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
H E +IAHRDIK EN++ +N N+++ DFG S +S+N + +T CGS+SYA+PE++
Sbjct: 125 HNECKIAHRDIKAENIVFDSNRNIRIIDFGLSN-SPDSNN---IMQTQCGSVSYASPEMI 180
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
G+ Y +D+WSLG++L+ M+ +PF DT +L ++ + K+ + S+ LS EC
Sbjct: 181 MGQKY-TYASDVWSLGILLYGMVCGHLPFQDTNYSRLAQKIVFKEVDYPSQ----LSSEC 235
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWIA 284
++K +L+ + R + WI+
Sbjct: 236 IDLLKRILKKNQADRIPLNEIEKHPWIS 263
Score = 138 bits (335), Expect = 3e-31
Identities = 74/216 (34%), Positives = 126/216 (58%), Gaps = 10/216 (4%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
REI+++ KL HP + + + + +I M + + G LLE + RG++ E+ A I Q
Sbjct: 57 REIDIMKKLKHPFVCDLYEVVETEKNVYIVMEFAQNGTLLETIKSRGSLGEEDASIIFAQ 116
Query: 434 LALAIQYMH-ELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSL 492
L + ++Y+H E +IAHRDIK EN++ +N+N+++ DFG + N I +T CGS+
Sbjct: 117 LLIVMKYLHNECKIAHRDIKAENIVFDSNRNIRIIDFGLSN---SPDSNNI-MQTQCGSV 172
Query: 493 SYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRY 552
SY +PE++ G Y +DVWSLGI++Y M+ +PF+D + +L Q + K + S+
Sbjct: 173 SYASPEMIMGQKY-TYASDVWSLGILLYGMVCGHLPFQDTNYSRLAQKIVFKEVDYPSQ- 230
Query: 553 IDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
+S C L+ +L+ N +R+ + +I WI+
Sbjct: 231 ---LSSECIDLLKRILKKNQADRIPLNEIEKHPWIS 263
>UniRef50_A4IFZ4 Cluster: LOC565828 protein; n=2; Euteleostomi|Rep:
LOC565828 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 500
Score = 145 bits (351), Expect = 4e-33
Identities = 96/313 (30%), Positives = 162/313 (51%), Gaps = 22/313 (7%)
Query: 7 TPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVK 66
T E+ + + K Y + +G+G++ V E + E K A K + KA V K
Sbjct: 36 TRIEDESSIQKIYSFGRKLGQGSFGVV--CEATHIETQRK--WAIKKVNKEKAGTSGV-K 90
Query: 67 FLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVW 126
L RE+ ++ ++ H H+IH+ +F+ + Y+ E GDL + KN +E + R
Sbjct: 91 HLEREVSIMKQVKHEHIIHLEEVFETPKRMYLVTELCEGGDLKDLLQKNKHFTEEETRHI 150
Query: 127 TRQLALGLQYLHELEIAHRDIKCENVLLTA--------NFNVKLSDFGFS--RFCVESDN 176
+ L+ + YLH+ +I HRD+K EN+L+ + N+K++DFG S + V S+N
Sbjct: 151 IKSLSEAIVYLHKKDIVHRDLKLENILVKSCHQGNDNDMVNIKVTDFGLSVQKGGVGSEN 210
Query: 177 QPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ 236
+ + CG+ Y APE++ G Y + DLWS+GV+++++L PF + +L E
Sbjct: 211 ---MLQATCGTPIYMAPEVVNGHQY-SQQCDLWSIGVIMYMLLCGEPPFGSSSKERLSEM 266
Query: 237 QMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMD--SRLTTLNA 294
M + F V + +S K V++ LL+ DP R +A +LD+ WI+ D + +T N
Sbjct: 267 IMKGELTFSGPVWNTISDAAKNVIRCLLKVDPAHRITANELLDNPWISGDTSTAVTRTNV 326
Query: 295 VE-AAALKRAKED 306
+E + A ED
Sbjct: 327 LEMMRQFRNAPED 339
Score = 115 bits (277), Expect = 3e-24
Identities = 63/230 (27%), Positives = 126/230 (54%), Gaps = 10/230 (4%)
Query: 370 KFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARI 429
K L RE+ ++ ++ H H++H +F+ + ++ E GDL + + + E++ R
Sbjct: 90 KHLEREVSIMKQVKHEHIIHLEEVFETPKRMYLVTELCEGGDLKDLLQKNKHFTEEETRH 149
Query: 430 WTRQLALAIQYMHELEIAHRDIKCENVLL-TANQ-------NVKLSDFGFARMCVDKKLN 481
+ L+ AI Y+H+ +I HRD+K EN+L+ + +Q N+K++DFG + + +
Sbjct: 150 IIKSLSEAIVYLHKKDIVHRDLKLENILVKSCHQGNDNDMVNIKVTDFGLS-VQKGGVGS 208
Query: 482 EIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQ 541
E + CG+ Y APE++ G Y + D+WS+G+++Y++L PF ++L +
Sbjct: 209 ENMLQATCGTPIYMAPEVVNGHQY-SQQCDLWSIGVIMYMLLCGEPPFGSSSKERLSEMI 267
Query: 542 INKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDS 591
+ F +TISD K +I +L+ + +R+ +++++ WI+ D+
Sbjct: 268 MKGELTFSGPVWNTISDAAKNVIRCLLKVDPAHRITANELLDNPWISGDT 317
>UniRef50_A5DRU5 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 1056
Score = 145 bits (351), Expect = 4e-33
Identities = 99/336 (29%), Positives = 166/336 (49%), Gaps = 18/336 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKF-LPREIDVLVR 77
Y L +GEG + KV L K+ H S +A K+I+ + KD + + REI+ L
Sbjct: 122 YILGSTLGEGEFGKVKLGW--RKDGKHPSQVAIKLIKRSTIVKDSDSEVKIHREINSLKM 179
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
LNHP+++++ + + I + Y G+L YIL++ + E A+ QL G+ YL
Sbjct: 180 LNHPNIVNLVEVMKSGKYVGIVLEYASGGELFDYILQHKYLKEPVAKKIFAQLVSGVDYL 239
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPE-IL 196
H ++ HRD+K EN+LL + NV +SDFGF N L +T CGS YAAPE +L
Sbjct: 240 HSKQLIHRDLKLENLLLDKHKNVIISDFGFVNSFNREHND--LMKTSCGSPCYAAPELVL 297
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDD-------TRMRKLYEQQMGKKYRFRSRVA 249
PY + D+WSLG++L+ ML+ +PFDD + + KLY F V+
Sbjct: 298 TQSPYEGRKVDIWSLGIILYAMLSGYLPFDDDPENEDGSDIIKLYHYICKTPLTFPEYVS 357
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKEDRRK 309
+ + +++ ++ DP R + + + ++ S L ++ E + + K+
Sbjct: 358 PL----ARDLLRKIIVSDPRKRATLDTIRNHPFLTPYSSLLSIRQPEWDRIHQQKQQPPS 413
Query: 310 LSDVHKHPP-KRQGDILEGPTRESAFRVYLAEYRNA 344
+HP ++ + PT S+ + +Y N+
Sbjct: 414 ELVEQQHPGINKRYSMFNAPTNSSSLVMPAMQYHNS 449
Score = 124 bits (300), Expect = 6e-27
Identities = 78/251 (31%), Positives = 136/251 (54%), Gaps = 9/251 (3%)
Query: 286 DSRLTTLNAVEAAALKRAKEDRRKLSDVHK--HPPKRQGDILEGPTR-ESAFRVYLAEYR 342
+++L T ++ + ++ + ++ K H R G+ + G T E F +R
Sbjct: 82 NTQLATPHSTSSTSISSQMHNNLNHPNIAKKMHREIRFGNYILGSTLGEGEFGKVKLGWR 141
Query: 343 NASKNDKLSILACKVIDTSTAPRDFVKKF-LPREIEMLIKLSHPHLVHTHSIFQRRYKYF 401
K+ S +A K+I ST +D + + REI L L+HP++V+ + +
Sbjct: 142 KDGKHP--SQVAIKLIKRSTIVKDSDSEVKIHREINSLKMLNHPNIVNLVEVMKSGKYVG 199
Query: 402 IFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTAN 461
I + Y G+L +++LQ ++E A+ QL + Y+H ++ HRD+K EN+LL +
Sbjct: 200 IVLEYASGGELFDYILQHKYLKEPVAKKIFAQLVSGVDYLHSKQLIHRDLKLENLLLDKH 259
Query: 462 QNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPE-ILQGTPYLPKPTDVWSLGIVVY 520
+NV +SDFGF +++ N++ +T CGS Y APE +L +PY + D+WSLGI++Y
Sbjct: 260 KNVIISDFGFVN-SFNREHNDL-MKTSCGSPCYAAPELVLTQSPYEGRKVDIWSLGIILY 317
Query: 521 VMLNRAMPFED 531
ML+ +PF+D
Sbjct: 318 AMLSGYLPFDD 328
>UniRef50_Q12263 Cluster: Serine/threonine-protein kinase GIN4; n=4;
Eukaryota|Rep: Serine/threonine-protein kinase GIN4 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 1142
Score = 145 bits (351), Expect = 4e-33
Identities = 75/213 (35%), Positives = 128/213 (60%), Gaps = 8/213 (3%)
Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127
+ REI ++ LNHP+++ ++ +++ T Y+ + Y E G+L + +++ G + E++A +
Sbjct: 78 IEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFF 137
Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGS 187
RQ+ +G+ Y H L I HRD+K EN+LL +N+K++DFG + +E++ + L ET CGS
Sbjct: 138 RQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMA--ALETEGK--LLETSCGS 193
Query: 188 MSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFD--DTRMRKLYEQQMGKKYRFR 245
YAAPEI+ G PY +D+WS GV+LF +L +PFD D +R L + +K F
Sbjct: 194 PHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKV--QKGEFE 251
Query: 246 SRVASILSLECKTVVKHLLEPDPGLRHSATNVL 278
+S E + +++ +L DP R ++L
Sbjct: 252 MPSDDEISREAQDLIRKILTVDPERRIKTRDIL 284
Score = 140 bits (338), Expect = 1e-31
Identities = 83/265 (31%), Positives = 142/265 (53%), Gaps = 14/265 (5%)
Query: 361 STAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRG 420
ST P D + + REI ++ L+HP+++ + +++ ++ + Y E+G+L +++RG
Sbjct: 68 STTP-DALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERG 126
Query: 421 AVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKL 480
+ E +A + RQ+ + + Y H L I HRD+K EN+LL N+K++DFG A + + KL
Sbjct: 127 PLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKL 186
Query: 481 NEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF--EDKHIKQLH 538
ET CGS Y APEI+ G PY +DVWS G++++ +L +PF ED +I+ L
Sbjct: 187 ----LETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTL- 241
Query: 539 QAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI-----AMDSRL 593
++ K +F D IS + LI +L + + R+K DI+ + DS+
Sbjct: 242 LLKVQKG-EFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKYPSIRDSKS 300
Query: 594 LEWTPQETLAYKKAREEKNKLHKTV 618
+ P+E E + + T+
Sbjct: 301 IRGLPREDTYLTPLSESNSSIDATI 325
>UniRef50_UPI00006CA3B2 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 793
Score = 144 bits (350), Expect = 5e-33
Identities = 133/596 (22%), Positives = 280/596 (46%), Gaps = 42/596 (7%)
Query: 18 GYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVR 77
GY++ K +G G++ VYL +E + K+ KI + K + + L E +L
Sbjct: 16 GYEVIKELGRGSFGVVYLGIKQGEELAIKTIKKDKIQRSQK-----LTELLDSEKQLLST 70
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
+ H+ + F+ ++ M Y G L YI + +SE +A+ + QL G + L
Sbjct: 71 IKSNHITKLFEFFETDKNCFLAMEYCNGGTLEKYIQQKKLISEKEAKGYLIQLLSGFKDL 130
Query: 138 HELEIAHRDIKCENVLL-------------TANFNVKLSDFGFSRFCVESDNQPVLSETY 184
H + HRDIK EN++ N +K++D G ++ E ++ +++ TY
Sbjct: 131 HSHLVIHRDIKLENIMRHFPNGQTGNDTYDNKNVVLKIADLGLAK---EMKDE-MIAHTY 186
Query: 185 CGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRF 244
G++ APEIL+ K Y D++SLGV+L+ M+ PF + KL ++ + +F
Sbjct: 187 AGTVLTMAPEILKQKSY-GFEVDVYSLGVILYYMVQGKYPFYENNDTKLLQKIKEQNIQF 245
Query: 245 RSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTT---LNAVEAAALK 301
+ + +SLE + ++K +L+ + R + + +++ + I +++LT + + +
Sbjct: 246 KDE--NPVSLEFQDLIKQMLKYNKKQRITWSGIINHKAIQPENQLTVSQRFDKCQNEEIS 303
Query: 302 RAKEDRRKLSDVH----KHPPKRQGDILEGPTRESAFRVYLAEYRNASKNDKLSILACKV 357
+K K+SD++ K P + L T+ + YLA + ++KL I+ +
Sbjct: 304 SSKVGFEKISDLYEIQNKLPQYQCKQKLIPITQNNFVNNYLA--IDTDNSNKLVIVKQVI 361
Query: 358 IDTSTAPR-DFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFV 416
D T + + + +++ K++ +++ + I + K++I Y++ G+L
Sbjct: 362 SDYYTLKEYNQTADQIKQVFKIIQKINQENILKINLITMSKNKFYIVSEYLKYGNLQTIN 421
Query: 417 LQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLT-ANQNVK-LSDF---GF 471
+ + + + ++++++HE I HR+I +++ + N+++ ++ F GF
Sbjct: 422 STNKKFLQQEILLLLINILISLKWLHENGIIHRNINLKSIYIAKLNESINFITQFKLGGF 481
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
++ + + G YTAPEIL Y + D++SLG+V++ ++ +P+
Sbjct: 482 KNCYKFEQRSSYAKSKYKGMNFYTAPEILSDKIY-TQTVDIYSLGVVLHELVYGYVPYIG 540
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
++L N+ K ++ S LI M+ P+ + R+ + + + I
Sbjct: 541 NTKQELIDNIYNQR-KNHDTEVEGFSKELLELIEKMIIPDPKQRINFEQLWSQDLI 595
>UniRef50_Q4SAD5 Cluster: Chromosome 13 SCAF14688, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
SCAF14688, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 829
Score = 144 bits (350), Expect = 5e-33
Identities = 69/214 (32%), Positives = 121/214 (56%), Gaps = 10/214 (4%)
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
REI +L + HPH++ +H +++ K Y+ + + G+L Y++K G ++ +AR + RQ
Sbjct: 146 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 205
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
+ L + H I HRD+K EN+LL N++++DFG + V L ET CGS
Sbjct: 206 IMSALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDS----LLETSCGSPH 261
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ-QMGKKYRFRSRV 248
YA PE++RG+ Y + D+WS GV+LF +L ++PFDD +R L E+ ++G + +
Sbjct: 262 YACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRNLLEKVKLGVFH-----M 316
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
+ +C+ +++ ++E D R + + W
Sbjct: 317 PHFIPPDCQNLLRGMIEVDASKRLTLEQIQKHTW 350
Score = 133 bits (322), Expect = 1e-29
Identities = 65/213 (30%), Positives = 120/213 (56%), Gaps = 8/213 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
REI +L + HPH++ H +++ + ++ + ++ G+L ++++++G + +AR + RQ
Sbjct: 146 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 205
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+ A+ + H I HRD+K EN+LL N++++DFG A + V L ET CGS
Sbjct: 206 IMSALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSL----LETSCGSPH 261
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
Y PE+++G Y + DVWS G++++ +L A+PF+D +++ L + K F +
Sbjct: 262 YACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRNLLEKV--KLGVFHMPHF 319
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
I +C+ L+ M+E + RL + I W
Sbjct: 320 --IPPDCQNLLRGMIEVDASKRLTLEQIQKHTW 350
>UniRef50_Q5Z6X0 Cluster: Putative wpk4 protein kinase; n=4; Oryza
sativa|Rep: Putative wpk4 protein kinase - Oryza sativa
subsp. japonica (Rice)
Length = 514
Score = 144 bits (350), Expect = 5e-33
Identities = 80/281 (28%), Positives = 146/281 (51%), Gaps = 14/281 (4%)
Query: 7 TPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVK 66
T ++ + T+ Y+ VGEG +AKVYL + + + +A K+++ K + +
Sbjct: 9 TGTKPPAMTTERYEFGPLVGEGNFAKVYLGRHRATGEE----VAIKVMDKEKLVRLGATE 64
Query: 67 FLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGC-----VSEN 121
+ REI V+ RL HP+++ +H + K + + M Y G L Y + + E+
Sbjct: 65 LIKREIAVMQRLRHPNVVRIHEVMANKRRICVVMEYVRGGALYRYFRRGPSGGAAGLREH 124
Query: 122 QARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLS 181
+AR + +QL + Y H + HRDIK +N+L+ N+K++DFG S + + +
Sbjct: 125 EARRFFQQLVSAVAYCHSRGVFHRDIKLDNLLVDEQGNLKVADFGLSALA-DMERREAHL 183
Query: 182 ETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKK 241
+T CG+ + APE+ + + Y D+W+ GVVL+V+L PF D + +LY + +G+
Sbjct: 184 QTVCGTPLFLAPEVFKRRGYDGAKADVWACGVVLYVLLTGRKPFPDEHVSRLY-RLIGQN 242
Query: 242 YRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
+ + S + +V+ LL+PDP R + +++ W
Sbjct: 243 ---QFQCPPSFSPDLARLVRRLLQPDPDRRITIPEIMEMRW 280
Score = 132 bits (319), Expect = 3e-29
Identities = 77/258 (29%), Positives = 138/258 (53%), Gaps = 17/258 (6%)
Query: 335 RVYLAEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIF 394
+VYL +R + +A KV+D R + + REI ++ +L HP++V H +
Sbjct: 34 KVYLGRHRATGEE-----VAIKVMDKEKLVRLGATELIKREIAVMQRLRHPNVVRIHEVM 88
Query: 395 QRRYKYFIFMRYMERGDLLEFVLQRG------AVQEDQARIWTRQLALAIQYMHELEIAH 448
+ + + M Y+ G L + +RG ++E +AR + +QL A+ Y H + H
Sbjct: 89 ANKRRICVVMEYVRGGALYRY-FRRGPSGGAAGLREHEARRFFQQLVSAVAYCHSRGVFH 147
Query: 449 RDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPK 508
RDIK +N+L+ N+K++DFG + + D + E +T CG+ + APE+ + Y
Sbjct: 148 RDIKLDNLLVDEQGNLKVADFGLSALA-DMERREAHLQTVCGTPLFLAPEVFKRRGYDGA 206
Query: 509 PTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLML 568
DVW+ G+V+YV+L PF D+H+ +L++ I +N +F+ + S + RL+ +L
Sbjct: 207 KADVWACGVVLYVLLTGRKPFPDEHVSRLYRL-IGQN-QFQCP--PSFSPDLARLVRRLL 262
Query: 569 EPNHQNRLKIYDIVNSEW 586
+P+ R+ I +I+ W
Sbjct: 263 QPDPDRRITIPEIMEMRW 280
>UniRef50_A7RVS7 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 335
Score = 144 bits (350), Expect = 5e-33
Identities = 82/269 (30%), Positives = 138/269 (51%), Gaps = 12/269 (4%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDV 74
L+K Y + + +G G +AKV L + + + +A K++ D + + RE++
Sbjct: 10 LSKYYDVRETIGSGGFAKVKLAVHRTSGEK----VAIKMMNKEALGHD--LPRVQRELEA 63
Query: 75 LVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGL 134
+ L H H+ ++ + + Y+ + Y + G+L YI+ + E++AR + RQ+ +
Sbjct: 64 MKDLCHQHICQLYHVIETDENIYMVLEYAQGGELFDYIVAKDRLKEDEARGFFRQIISAV 123
Query: 135 QYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPE 194
Y+HE AHRD+K EN+LL N+KL DFG ET CGS +YAAPE
Sbjct: 124 AYIHEKGYAHRDLKPENLLLDEEQNIKLIDFGL--VAKPEGGMTEQLETCCGSPAYAAPE 181
Query: 195 ILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSL 254
++ G PY DLWS+GV+L+ ++ +PFDD KLY +Y + S LS
Sbjct: 182 LISGLPYFGNEVDLWSMGVLLYALVCGFLPFDDDNTYKLYRLIQKGEY----EIPSWLSQ 237
Query: 255 ECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
++ LL+ P R ++++ +W+
Sbjct: 238 GTVAILGQLLQVSPRKRAKIQDLVNHDWV 266
Score = 144 bits (349), Expect = 7e-33
Identities = 70/235 (29%), Positives = 132/235 (56%), Gaps = 8/235 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+++ D + + RE+E + L H H+ + + + ++ + Y + G+L
Sbjct: 40 VAIKMMNKEALGHDLPR--VQRELEAMKDLCHQHICQLYHVIETDENIYMVLEYAQGGEL 97
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++ + ++ED+AR + RQ+ A+ Y+HE AHRD+K EN+LL QN+KL DFG
Sbjct: 98 FDYIVAKDRLKEDEARGFFRQIISAVAYIHEKGYAHRDLKPENLLLDEEQNIKLIDFGLV 157
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
++ ET CGS +Y APE++ G PY D+WS+G+++Y ++ +PF+D
Sbjct: 158 AKPEGGMTEQL--ETCCGSPAYAAPELISGLPYFGNEVDLWSMGVLLYALVCGFLPFDDD 215
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ +L++ ++ S +S ++G +L+ + + R KI D+VN +W+
Sbjct: 216 NTYKLYRLIQKGEYEIPS----WLSQGTVAILGQLLQVSPRKRAKIQDLVNHDWV 266
>UniRef50_A2F749 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 325
Score = 144 bits (350), Expect = 5e-33
Identities = 79/260 (30%), Positives = 134/260 (51%), Gaps = 13/260 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y++ +G G+ V+ ++K + L KIIE + ++F RE+ +L L
Sbjct: 8 YQIFGEIGRGSSGSVH----TAKNTQNNQELCVKIIEKSSMNTKEDIEFFRREVSILSAL 63
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
H ++ H + + YY+F + +L Y+ N +SE Q + Q L Y+H
Sbjct: 64 QHKNIAEYHDLLEDSNNYYLFQELCQGENLTKYLENNRPISERQIEIIFHQFCSALSYIH 123
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ + HRD+K +N+++ AN VK+ DFG S DNQ L T+CGS++YAAPE +R
Sbjct: 124 KAGVGHRDLKPDNIIIGANNIVKIIDFGLS----TDDNQH-LRTTFCGSLAYAAPECIRR 178
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+PY +D+WSLGV+LF M +P+ + + +L +Q + + + + K
Sbjct: 179 EPYIAWRSDMWSLGVILFQMNTGRLPWKTSNIVQLMKQITSGNFEIPPSIPAPI----KN 234
Query: 259 VVKHLLEPDPGLRHSATNVL 278
++ L DP LR SA +++
Sbjct: 235 IIVQCLNQDPTLRPSADDLI 254
Score = 116 bits (280), Expect = 2e-24
Identities = 60/206 (29%), Positives = 111/206 (53%), Gaps = 8/206 (3%)
Query: 342 RNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYF 401
+N N +L + K+I+ S+ +F RE+ +L L H ++ H + + Y+
Sbjct: 26 KNTQNNQELCV---KIIEKSSMNTKEDIEFFRREVSILSALQHKNIAEYHDLLEDSNNYY 82
Query: 402 IFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTAN 461
+F + +L +++ + E Q I Q A+ Y+H+ + HRD+K +N+++ AN
Sbjct: 83 LFQELCQGENLTKYLENNRPISERQIEIIFHQFCSALSYIHKAGVGHRDLKPDNIIIGAN 142
Query: 462 QNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYV 521
VK+ DFG + D N+ TFCGSL+Y APE ++ PY+ +D+WSLG++++
Sbjct: 143 NIVKIIDFG---LSTDD--NQHLRTTFCGSLAYAAPECIRREPYIAWRSDMWSLGVILFQ 197
Query: 522 MLNRAMPFEDKHIKQLHQAQINKNWK 547
M +P++ +I QL + + N++
Sbjct: 198 MNTGRLPWKTSNIVQLMKQITSGNFE 223
>UniRef50_A3LNK1 Cluster: Predicted protein; n=1; Pichia
stipitis|Rep: Predicted protein - Pichia stipitis
(Yeast)
Length = 1275
Score = 144 bits (350), Expect = 5e-33
Identities = 109/350 (31%), Positives = 176/350 (50%), Gaps = 31/350 (8%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDS------HKSTLACKIIETAKAPKDFVVKF-LPRE 71
+KL K +G GA +V L + + KS L + K D + + + RE
Sbjct: 27 WKLGKTLGRGATGRVLLATHQTTGQKAAVKVVSKSELHDEDQPVRKNSDDAGLPYGIERE 86
Query: 72 IDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLA 131
I ++ L HP+++ ++ +++ Y+ + Y E G+L +++ G + E +A + RQ+
Sbjct: 87 IIIMKLLTHPNVLRLYDVWETSKALYLVLEYVEGGELFDLLVERGPLQEVEAIKYFRQII 146
Query: 132 LGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYA 191
LG Y H L I HRD+K EN+LL A NVKL+DFG + +ES+ + L ET CGS YA
Sbjct: 147 LGTAYCHALGICHRDLKPENLLLDAALNVKLADFGMA--ALESNGK--LLETSCGSPHYA 202
Query: 192 APEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASI 251
APEI+ G Y +D+WS GV+LF +L +PFDD +R L + + +
Sbjct: 203 APEIVSGLKYHGAASDVWSCGVILFALLTGRLPFDDENIRNLLLKVQAGNFDMPDEI--- 259
Query: 252 LSLECKTVVKHLLEPDPGLRHSATNVLD----SEWIAMDSRLTTLNAV---EAA--ALKR 302
S E + ++ +L DP R VL+ +++ + L ++ ++ E A +L
Sbjct: 260 -SPEAQDLIGRMLTVDPIKRIPTEKVLNHALLTKYPIPNEDLISVKSLPHPETAYKSLGS 318
Query: 303 AKE-DRRKLSDV----HKHPPKRQGDIL--EGPTRESAFRVYLAEYRNAS 345
AK D++ LS++ H P + + L GP E F L YR+ S
Sbjct: 319 AKNIDKQILSNLSILWHDRPQQEIINCLLKNGPNPEKTFYALLLRYRHNS 368
Score = 138 bits (334), Expect = 4e-31
Identities = 91/281 (32%), Positives = 148/281 (52%), Gaps = 17/281 (6%)
Query: 311 SDVHKHPPKRQGDILEGPT--RESAFRVYLAEYRNASKNDKLSILACKVIDTSTAP--RD 366
S H HP K G G T R + RV LA ++ + + +++ + P ++
Sbjct: 15 STSHNHPQKI-GPWKLGKTLGRGATGRVLLATHQTTGQKAAVKVVSKSELHDEDQPVRKN 73
Query: 367 FVKKFLP----REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAV 422
LP REI ++ L+HP+++ + +++ ++ + Y+E G+L + +++RG +
Sbjct: 74 SDDAGLPYGIEREIIIMKLLTHPNVLRLYDVWETSKALYLVLEYVEGGELFDLLVERGPL 133
Query: 423 QEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNE 482
QE +A + RQ+ L Y H L I HRD+K EN+LL A NVKL+DFG A + + KL
Sbjct: 134 QEVEAIKYFRQIILGTAYCHALGICHRDLKPENLLLDAALNVKLADFGMAALESNGKL-- 191
Query: 483 IRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQI 542
ET CGS Y APEI+ G Y +DVWS G++++ +L +PF+D++I+ L
Sbjct: 192 --LETSCGSPHYAAPEIVSGLKYHGAASDVWSCGVILFALLTGRLPFDDENIRNLLLKVQ 249
Query: 543 NKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVN 583
N+ D IS + LIG ML + R+ ++N
Sbjct: 250 AGNFDMP----DEISPEAQDLIGRMLTVDPIKRIPTEKVLN 286
>UniRef50_O74536 Cluster: SNF1-like protein kinase ssp2; n=3;
Schizosaccharomyces pombe|Rep: SNF1-like protein kinase
ssp2 - Schizosaccharomyces pombe (Fission yeast)
Length = 576
Score = 144 bits (350), Expect = 5e-33
Identities = 83/265 (31%), Positives = 141/265 (53%), Gaps = 15/265 (5%)
Query: 19 YKLTKFVGEGAYAKVYL-TEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVR 77
Y + + +GEG++ KV L T Y +++ +A K I K + + REI L
Sbjct: 34 YIIRETLGEGSFGKVKLATHYKTQQK-----VALKFISRQLLKKSDMHMRVEREISYLKL 88
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
L HPH+I ++ + T + + Y G+L YI++ ++E++ R + +Q+ ++Y
Sbjct: 89 LRHPHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYC 147
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H +I HRD+K EN+LL N NVK++DFG S + + +T CGS +YAAPE++
Sbjct: 148 HRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGN----FLKTSCGSPNYAAPEVIN 203
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
GK Y D+WS G+VL+VML +PFDD + L+++ Y + LS +
Sbjct: 204 GKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVY----VMPDFLSPGAQ 259
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEW 282
++++ ++ DP R + + W
Sbjct: 260 SLIRRMIVADPMQRITIQEIRRDPW 284
Score = 130 bits (315), Expect = 9e-29
Identities = 75/234 (32%), Positives = 122/234 (52%), Gaps = 9/234 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K I + + + REI L L HPH++ + + + + Y G+L
Sbjct: 60 VALKFISRQLLKKSDMHMRVEREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYAG-GEL 118
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
++++++ + ED+ R + +Q+ AI+Y H +I HRD+K EN+LL N NVK++DFG +
Sbjct: 119 FDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLS 178
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ D +T CGS +Y APE++ G Y DVWS GIV+YVML +PF+D+
Sbjct: 179 NIMTDGNF----LKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDE 234
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
I L + ++N D +S + LI M+ + R+ I +I W
Sbjct: 235 FIPNLFK-KVNSCVYVMP---DFLSPGAQSLIRRMIVADPMQRITIQEIRRDPW 284
>UniRef50_Q7ZU72 Cluster: Maternal embryonic leucine zipper kinase;
n=7; Euteleostomi|Rep: Maternal embryonic leucine zipper
kinase - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 676
Score = 144 bits (349), Expect = 7e-33
Identities = 88/278 (31%), Positives = 143/278 (51%), Gaps = 18/278 (6%)
Query: 8 PSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKF 67
P + + L + Y++ + +G G +AKV L + + +A KI+E D
Sbjct: 2 PVDSTSELLRHYEVYETIGSGGFAKVKLGRHKLTGEK----VAIKIMEKKDLGDD----- 52
Query: 68 LPR---EIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQAR 124
LPR EI+ + L+H H+ ++ + + +K Y+ + Y G+L YI+ +SE + R
Sbjct: 53 LPRVKIEIEAMKNLSHQHVCRLYHVIETTSKIYMVLEYCPGGELFDYIIAKDRLSEEETR 112
Query: 125 VWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETY 184
V+ RQ+ L Y+H AHRD+K EN+L+ + N+KL DFG +L T
Sbjct: 113 VFFRQIISALAYVHSQGYAHRDLKPENLLIDEDHNLKLIDFGLCAKPKGGLGFELL--TC 170
Query: 185 CGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRF 244
CGS +YAAPE+++GK Y D+WS+GV+L+ +L +PFDD LY + KY
Sbjct: 171 CGSPAYAAPELIQGKAYIGSEADVWSMGVLLYALLCGFLPFDDDNCMVLYRKITRGKY-- 228
Query: 245 RSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
LS ++ +++ DP R + ++LD W
Sbjct: 229 --SNPHWLSPSSILLLNQMMQVDPKRRLTVKHLLDHPW 264
Score = 128 bits (310), Expect = 3e-28
Identities = 71/238 (29%), Positives = 132/238 (55%), Gaps = 12/238 (5%)
Query: 372 LPR---EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQAR 428
LPR EIE + LSH H+ + + + K ++ + Y G+L ++++ + + E++ R
Sbjct: 53 LPRVKIEIEAMKNLSHQHVCRLYHVIETTSKIYMVLEYCPGGELFDYIIAKDRLSEEETR 112
Query: 429 IWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLN-EIRSET 487
++ RQ+ A+ Y+H AHRD+K EN+L+ + N+KL DFG +C K T
Sbjct: 113 VFFRQIISALAYVHSQGYAHRDLKPENLLIDEDHNLKLIDFG---LCAKPKGGLGFELLT 169
Query: 488 FCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWK 547
CGS +Y APE++QG Y+ DVWS+G+++Y +L +PF+D + L++ +I + K
Sbjct: 170 CCGSPAYAAPELIQGKAYIGSEADVWSMGVLLYALLCGFLPFDDDNCMVLYR-KITRG-K 227
Query: 548 FRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD-SRLLEWTPQETLAY 604
+ + + +S + L+ M++ + + RL + +++ W S +EW + L +
Sbjct: 228 YSNPH--WLSPSSILLLNQMMQVDPKRRLTVKHLLDHPWAMRGYSTPVEWHSKYPLGH 283
>UniRef50_Q4RK91 Cluster: Chromosome 18 SCAF15030, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 18
SCAF15030, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 689
Score = 144 bits (349), Expect = 7e-33
Identities = 89/275 (32%), Positives = 141/275 (51%), Gaps = 19/275 (6%)
Query: 15 LTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPR---E 71
L K Y+L + +G G +AKV L + + +A KI+ D LPR E
Sbjct: 14 LYKYYELYETIGSGGFAKVKLGRHILTGEK----VAIKIMNKRDLGDD-----LPRVKVE 64
Query: 72 IDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLA 131
I+ + L+H H+ ++ + + T+ ++ M Y G+L YI+ +SE + RV+ RQ+
Sbjct: 65 IEAMKNLSHQHICRLYHVIETSTQIFMVMEYCTGGELFDYIIAKDRLSEEETRVFFRQIV 124
Query: 132 LGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYA 191
+ Y+H AHRD+K EN+L+ + N+KL DFG C + T CGS +YA
Sbjct: 125 SAMAYVHSQGYAHRDLKPENLLIDEDHNLKLIDFG---LCAITKGLGYELMTCCGSPAYA 181
Query: 192 APEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASI 251
APE+++GK Y D+WS+GV+LF +L +PFDD LY + KY R S
Sbjct: 182 APELIQGKAYIGSEADVWSMGVLLFALLCGYLPFDDDNCMILYRKITRGKYD-NPRWLSP 240
Query: 252 LSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMD 286
S+ ++ +++ DP R + +L W+ D
Sbjct: 241 GSI---LLLNQMMQVDPKRRLTVEQLLGHPWVIKD 272
Score = 136 bits (330), Expect = 1e-30
Identities = 72/237 (30%), Positives = 131/237 (55%), Gaps = 11/237 (4%)
Query: 372 LPR---EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQAR 428
LPR EIE + LSH H+ + + + + F+ M Y G+L ++++ + + E++ R
Sbjct: 58 LPRVKVEIEAMKNLSHQHICRLYHVIETSTQIFMVMEYCTGGELFDYIIAKDRLSEEETR 117
Query: 429 IWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETF 488
++ RQ+ A+ Y+H AHRD+K EN+L+ + N+KL DFG +C K T
Sbjct: 118 VFFRQIVSAMAYVHSQGYAHRDLKPENLLIDEDHNLKLIDFG---LCAITKGLGYELMTC 174
Query: 489 CGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKF 548
CGS +Y APE++QG Y+ DVWS+G++++ +L +PF+D + L++ +I +
Sbjct: 175 CGSPAYAAPELIQGKAYIGSEADVWSMGVLLFALLCGYLPFDDDNCMILYR-KITRGKYD 233
Query: 549 RSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMD-SRLLEWTPQETLAY 604
R+ +S L+ M++ + + RL + ++ W+ D + +EW Q+ L +
Sbjct: 234 NPRW---LSPGSILLLNQMMQVDPKRRLTVEQLLGHPWVIKDYNSPVEWHSQQPLGH 287
>UniRef50_Q54PB4 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 481
Score = 144 bits (349), Expect = 7e-33
Identities = 88/284 (30%), Positives = 147/284 (51%), Gaps = 13/284 (4%)
Query: 8 PSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSK-EDSHKSTLACKIIETAKAPKDFVVK 66
PS N + Y +T +GEG ++ V L + K ED + A KII +
Sbjct: 2 PSNPNRSIYDFYNITDIIGEGTFSTVTLANHIEKIEDKY----AIKIISKEVLDNERRT- 56
Query: 67 FLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVW 126
++ EI +L + HP++I + ++ + + + NGDL I+K G +E +AR+
Sbjct: 57 YVDWEISILSKCQHPNIIKFYEHYESDEDICLVLEWIPNGDLFDRIVKKGVFNEEEARLT 116
Query: 127 TRQLALGLQYLHELEIAHRDIKCENVLLTANF-NVKLSDFGFSRFCVESDNQPVLSETYC 185
+ L ++YLH+ + HRDIK EN+L + ++ +KL DFG ++F ES + E C
Sbjct: 117 MKSLLSAVEYLHDKSVVHRDIKPENILFSDSYGGIKLGDFGLAKFYEES----IGLELAC 172
Query: 186 GSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFR 245
G+++Y+APEI + Y K D+WS G +L+ +L PF +++E ++ F
Sbjct: 173 GTLAYSAPEITNNQVY-RKSVDMWSCGCILYFILFGRPPFYSDDESEMFELITKGQWEFP 231
Query: 246 SRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI-AMDSR 288
S+ S + K ++K LLE DP R + L +WI ++D R
Sbjct: 232 SKTQHKYSDQVKDLIKLLLENDPNKRLTVKQSLAHKWIQSIDER 275
Score = 128 bits (308), Expect = 6e-28
Identities = 68/226 (30%), Positives = 121/226 (53%), Gaps = 7/226 (3%)
Query: 369 KKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQAR 428
+ ++ EI +L K HP+++ + ++ + + ++ GDL + ++++G E++AR
Sbjct: 55 RTYVDWEISILSKCQHPNIIKFYEHYESDEDICLVLEWIPNGDLFDRIVKKGVFNEEEAR 114
Query: 429 IWTRQLALAIQYMHELEIAHRDIKCENVLLTANQ-NVKLSDFGFARMCVDKKLNEIRSET 487
+ + L A++Y+H+ + HRDIK EN+L + + +KL DFG A+ + I E
Sbjct: 115 LTMKSLLSAVEYLHDKSVVHRDIKPENILFSDSYGGIKLGDFGLAKFYEE----SIGLEL 170
Query: 488 FCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWK 547
CG+L+Y+APEI Y K D+WS G ++Y +L PF ++ + W+
Sbjct: 171 ACGTLAYSAPEITNNQVY-RKSVDMWSCGCILYFILFGRPPFYSDDESEMFELITKGQWE 229
Query: 548 FRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI-AMDSR 592
F S+ SD K LI L+LE + RL + + +WI ++D R
Sbjct: 230 FPSKTQHKYSDQVKDLIKLLLENDPNKRLTVKQSLAHKWIQSIDER 275
>UniRef50_A2ESJ5 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 494
Score = 144 bits (349), Expect = 7e-33
Identities = 75/213 (35%), Positives = 123/213 (57%), Gaps = 9/213 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y + K +GEG AKV L S D+ K +A K+I+ K + + REI ++ L
Sbjct: 8 YTVIKDLGEGTSAKVKLC---SDPDTGKK-VAIKVIKKESFEKQDFKRKIMREIALMQFL 63
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP+LI ++ +++ Y+ + Y G+L Y++ + A + RQ+ G++YLH
Sbjct: 64 KHPYLIELYEVYESTNHLYMILEYAPKGELFDYLVSRRFLKPETALHFFRQIIYGIEYLH 123
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I HRD+K EN+L+ + N+K++DFGF+R+ + ++T CGS YAAPE++RG
Sbjct: 124 ANSICHRDLKPENILIDEDENLKIADFGFARWMKTN-----TAKTSCGSPHYAAPEVIRG 178
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMR 231
+ Y + D+WS GV+LF ++ +PFDD +R
Sbjct: 179 QQYDGRIADVWSCGVILFALVAGYLPFDDPSVR 211
Score = 129 bits (312), Expect = 2e-28
Identities = 61/197 (30%), Positives = 116/197 (58%), Gaps = 5/197 (2%)
Query: 339 AEYRNASKNDKLSILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRY 398
A+ + S D +A KVI + + K+ + REI ++ L HP+L+ + +++
Sbjct: 20 AKVKLCSDPDTGKKVAIKVIKKESFEKQDFKRKIMREIALMQFLKHPYLIELYEVYESTN 79
Query: 399 KYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLL 458
++ + Y +G+L ++++ R ++ + A + RQ+ I+Y+H I HRD+K EN+L+
Sbjct: 80 HLYMILEYAPKGELFDYLVSRRFLKPETALHFFRQIIYGIEYLHANSICHRDLKPENILI 139
Query: 459 TANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIV 518
++N+K++DFGFAR K N ++T CGS Y APE+++G Y + DVWS G++
Sbjct: 140 DEDENLKIADFGFARW---MKTN--TAKTSCGSPHYAAPEVIRGQQYDGRIADVWSCGVI 194
Query: 519 VYVMLNRAMPFEDKHIK 535
++ ++ +PF+D ++
Sbjct: 195 LFALVAGYLPFDDPSVR 211
>UniRef50_A0DBM2 Cluster: Chromosome undetermined scaffold_44, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_44,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 536
Score = 144 bits (349), Expect = 7e-33
Identities = 77/250 (30%), Positives = 131/250 (52%), Gaps = 12/250 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y L K +G G++ KV L ++ + +A K+I + + + REI +
Sbjct: 14 YLLGKTLGVGSFGKVKLARHNITN----TQVAIKVINKKRMKNSKMEDKISREIRYMRHF 69
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
NHP++I ++ + + ++ M Y E G+L I + G + E +AR Q+ G+ Y H
Sbjct: 70 NHPNVIKLYEVLETAGDVFVVMEYAEKGELFDLIAQRGKLPETEARNLFLQILSGVDYCH 129
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+AHRD+K EN+L++ N +K+ DFG S N +T CGS +YAAPE++ G
Sbjct: 130 NNLVAHRDLKPENILISHNNTLKIGDFGLS----NKMNDGEYLKTPCGSPNYAAPEVISG 185
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ YC D+WS GV+LF ++ +PFD+ + LY++ Y + + S + +
Sbjct: 186 RTYCGTEADVWSCGVILFALIAGYLPFDEETSQALYKKIKTADY----IIPNSFSPQVRD 241
Query: 259 VVKHLLEPDP 268
++ +L PDP
Sbjct: 242 LINRMLTPDP 251
Score = 129 bits (312), Expect = 2e-28
Identities = 65/229 (28%), Positives = 122/229 (53%), Gaps = 8/229 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KVI+ ++ + REI + +HP+++ + + + F+ M Y E+G+L
Sbjct: 40 VAIKVINKKRMKNSKMEDKISREIRYMRHFNHPNVIKLYEVLETAGDVFVVMEYAEKGEL 99
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ + QRG + E +AR Q+ + Y H +AHRD+K EN+L++ N +K+ DFG +
Sbjct: 100 FDLIAQRGKLPETEARNLFLQILSGVDYCHNNLVAHRDLKPENILISHNNTLKIGDFGLS 159
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
D + +T CGS +Y APE++ G Y DVWS G++++ ++ +PF+++
Sbjct: 160 NKMNDGEY----LKTPCGSPNYAAPEVISGRTYCGTEADVWSCGVILFALIAGYLPFDEE 215
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDI 581
+ L++ ++ + + + D LI ML P+ R+K ++I
Sbjct: 216 TSQALYKKIKTADYIIPNSFSPQVRD----LINRMLTPDPLKRIKFHEI 260
>UniRef50_P22216 Cluster: Serine/threonine-protein kinase RAD53;
n=5; Saccharomycetales|Rep: Serine/threonine-protein
kinase RAD53 - Saccharomyces cerevisiae (Baker's yeast)
Length = 821
Score = 144 bits (349), Expect = 7e-33
Identities = 83/279 (29%), Positives = 148/279 (53%), Gaps = 24/279 (8%)
Query: 21 LTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNH 80
+ + VG+GA+A V + E + T A KII K + + + RE++VL +LNH
Sbjct: 200 IDEVVGQGAFATVK----KAIERTTGKTFAVKIISKRKVIGN--MDGVTRELEVLQKLNH 253
Query: 81 PHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHEL 140
P ++ + ++ YY+ M + GDL+ ++ +G V E+ R +RQ+ ++Y+H +
Sbjct: 254 PRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSM 313
Query: 141 EIAHRDIKCENVLLTAN--FNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
I+HRD+K +N+L+ + VK++DFG ++ V+ + +T+CG+++Y APE++RG
Sbjct: 314 GISHRDLKPDNILIEQDDPVLVKITDFGLAK--VQGNGS--FMKTFCGTLAYVAPEVIRG 369
Query: 199 KPYCPKP------------TDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRS 246
K P D+WS+G +++V+L +PF + +LY+Q Y
Sbjct: 370 KDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGP 429
Query: 247 RVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAM 285
+S E + + LL+ DP R +A L+ WI M
Sbjct: 430 LKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKM 468
Score = 132 bits (319), Expect = 3e-29
Identities = 78/231 (33%), Positives = 126/231 (54%), Gaps = 20/231 (8%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE+E+L KL+HP +V ++ Y++ M ++ GDL++FV GAV ED R +RQ
Sbjct: 243 RELEVLQKLNHPRIVRLKGFYEDTESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQ 302
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQN--VKLSDFGFARMCVDKKLNEIRSETFCGS 491
+ AI+Y+H + I+HRD+K +N+L+ + VK++DFG A++ + N +TFCG+
Sbjct: 303 ILTAIKYIHSMGISHRDLKPDNILIEQDDPVLVKITDFGLAKV----QGNGSFMKTFCGT 358
Query: 492 LSYTAPEILQGTPYLPKP------------TDVWSLGIVVYVMLNRAMPFEDKHIKQLHQ 539
L+Y APE+++G P D+WS+G +VYV+L +PF QL++
Sbjct: 359 LAYVAPEVIRGKDTSVSPDEYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYK 418
Query: 540 AQINKNWKFRSRYID-TISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAM 589
QI + D IS+ + I +L+ + NR +N WI M
Sbjct: 419 -QIGRGSYHEGPLKDFRISEEARDFIDSLLQVDPNNRSTAAKALNHPWIKM 468
>UniRef50_UPI0001561451 Cluster: PREDICTED: similar to
serine/threonine kinase; n=1; Equus caballus|Rep:
PREDICTED: similar to serine/threonine kinase - Equus
caballus
Length = 589
Score = 144 bits (348), Expect = 9e-33
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 14/267 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
YKL K +G+ +Y KV L + + +A K++E + K L E+ L +
Sbjct: 19 YKLLKTIGQSSYCKVKLARHLPTG----TEVAVKMVERSGKSASRA-KALHCEVQSLKTV 73
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP+++ + + + +I GDLL +I K+G ++E++AR RQLA L+Y H
Sbjct: 74 RHPNVLKLLEVVATEETSFIVSELVSGGDLLDHIRKSGPMAEDEARGKFRQLASALEYCH 133
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+AHRD++ E+VLL NVKLS FG S + + LS T CGS YAAPE L+G
Sbjct: 134 RKGVAHRDLRLEHVLLDGEGNVKLSGFGSSAVFLGQE----LS-TQCGSPWYAAPETLQG 188
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y P D+WSLGVVLF +L + PF + + + + ++ + LS EC+
Sbjct: 189 RAYAGPPADVWSLGVVLFFLLTGAPPFWGCDLATVRRRVLSGRF----PLPMFLSWECRN 244
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWIAM 285
++ +L +P R +A +L W+ M
Sbjct: 245 LLGKMLTLNPQKRITAKQILKDRWVNM 271
Score = 132 bits (319), Expect = 3e-29
Identities = 77/225 (34%), Positives = 118/225 (52%), Gaps = 9/225 (4%)
Query: 370 KFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARI 429
K L E++ L + HP+++ + FI + GDLL+ + + G + ED+AR
Sbjct: 61 KALHCEVQSLKTVRHPNVLKLLEVVATEETSFIVSELVSGGDLLDHIRKSGPMAEDEARG 120
Query: 430 WTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFC 489
RQLA A++Y H +AHRD++ E+VLL NVKLS FG + + + ++L+ T C
Sbjct: 121 KFRQLASALEYCHRKGVAHRDLRLEHVLLDGEGNVKLSGFGSSAVFLGQELS-----TQC 175
Query: 490 GSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFR 549
GS Y APE LQG Y P DVWSLG+V++ +L A PF + + + ++ +
Sbjct: 176 GSPWYAAPETLQGRAYAGPPADVWSLGVVLFFLLTGAPPFWGCDLATVRRRVLSGRFPLP 235
Query: 550 SRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLL 594
+S C+ L+G ML N Q R+ I+ W+ M L
Sbjct: 236 M----FLSWECRNLLGKMLTLNPQKRITAKQILKDRWVNMGQEKL 276
>UniRef50_A2QQQ6 Cluster: Function: S. pombe kin1 affects
composition or organization of the cell wall; n=9;
Eurotiomycetidae|Rep: Function: S. pombe kin1 affects
composition or organization of the cell wall -
Aspergillus niger
Length = 1075
Score = 144 bits (348), Expect = 9e-33
Identities = 70/214 (32%), Positives = 124/214 (57%), Gaps = 8/214 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE ++ ++HP++ + + Y +++ + G +L++++ G ++E QAR + RQ
Sbjct: 251 REAAIVSLVNHPYICGMRDVVRTNYHWYMLFELVNGGQMLDYIISHGKLKEKQARKFARQ 310
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+A A+ Y H I HRD+K EN+L++ ++K+ DFG + + + L +TFCGSL
Sbjct: 311 IASALDYCHRNSIVHRDLKIENILISKTGDIKIIDFGLSNLFSPRSL----LKTFCGSLY 366
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
+ APE+LQ Y DVWS GIV+YV++ +PF+D+ + +LH A+I K F Y
Sbjct: 367 FAAPELLQARQYTGPEVDVWSFGIVLYVLVCGKVPFDDQSMPKLH-AKI-KQGVF--EYP 422
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
++ C+ +I ML + + R + +I+N W+
Sbjct: 423 PGLTTECRHIISRMLVTDPKQRASLAEIMNHPWM 456
Score = 143 bits (347), Expect = 1e-32
Identities = 68/214 (31%), Positives = 118/214 (55%), Gaps = 8/214 (3%)
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
RE ++ +NHP++ + + + +Y+ G +L YI+ +G + E QAR + RQ
Sbjct: 251 REAAIVSLVNHPYICGMRDVVRTNYHWYMLFELVNGGQMLDYIISHGKLKEKQARKFARQ 310
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
+A L Y H I HRD+K EN+L++ ++K+ DFG S + L +T+CGS+
Sbjct: 311 IASALDYCHRNSIVHRDLKIENILISKTGDIKIIDFGLSNLF----SPRSLLKTFCGSLY 366
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
+AAPE+L+ + Y D+WS G+VL+V++ +PFDD M KL+ + + +
Sbjct: 367 FAAPELLQARQYTGPEVDVWSFGIVLYVLVCGKVPFDDQSMPKLHAKIKQGVFEYPPG-- 424
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
L+ EC+ ++ +L DP R S +++ W+
Sbjct: 425 --LTTECRHIISRMLVTDPKQRASLAEIMNHPWM 456
>UniRef50_P13186 Cluster: Serine/threonine-protein kinase KIN2; n=2;
Saccharomyces cerevisiae|Rep: Serine/threonine-protein
kinase KIN2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 1147
Score = 144 bits (348), Expect = 9e-33
Identities = 73/214 (34%), Positives = 121/214 (56%), Gaps = 8/214 (3%)
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
RE + L HPH+ + + +Y+ Y G LL YI+++G + E+ AR + R
Sbjct: 172 REASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARG 231
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
+A LQYLH I HRD+K EN++++++ +K+ DFG S D + L T+CGS+
Sbjct: 232 IASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNI---FDYRKQL-HTFCGSLY 287
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
+AAPE+L+ +PY D+WS G+VL+V++ +PFDD L+E+ K + S
Sbjct: 288 FAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSH-- 345
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
LS+E +++ ++ DP R + NV++ W+
Sbjct: 346 --LSIEVISLLTRMIVVDPLRRATLKNVVEHPWM 377
Score = 132 bits (319), Expect = 3e-29
Identities = 67/214 (31%), Positives = 119/214 (55%), Gaps = 8/214 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE + L HPH+ + +++ Y+ G LL++++Q G+++E AR + R
Sbjct: 172 REASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARG 231
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+A A+QY+H I HRD+K EN++++++ +K+ DFG + + +K + TFCGSL
Sbjct: 232 IASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRK----QLHTFCGSLY 287
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
+ APE+L+ PY D+WS GIV+YV++ +PF+D++ LH+ K K + Y
Sbjct: 288 FAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHE----KIKKGKVDYP 343
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+S L+ M+ + R + ++V W+
Sbjct: 344 SHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWM 377
>UniRef50_UPI0000E801CD Cluster: PREDICTED: hypothetical protein;
n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 591
Score = 143 bits (347), Expect = 1e-32
Identities = 85/268 (31%), Positives = 142/268 (52%), Gaps = 11/268 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKD-FVVKFLPREIDVLVR 77
Y + + + +G++AKV + + +A K+I+ KA +D +V+K + RE +
Sbjct: 18 YLVGRMINKGSFAKVMEGLHIPTGEK----VAIKVIDKRKAKQDSYVLKNMKREPRIHQM 73
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
+ HP+++ ++ + YY+ M GDLL I ++E + R +TRQ+ + YL
Sbjct: 74 IKHPNVVQLYETLETDNSYYMVMELCLGGDLLDRICDKQRLAEREVRRYTRQILSAVGYL 133
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H I HRD+K EN LL N N+K+ DFG S L T CGS +YAAPE+L
Sbjct: 134 HCHGIVHRDLKIENFLLDENDNIKIVDFGLSNTAKFEGLSQELLYTQCGSPAYAAPELLA 193
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPF--DDTRMRKLYEQQMGKKYRFRSRVASILSLE 255
+ Y PK D+WS+GV +F ML ++PF + +++L+++ + + S + S +S
Sbjct: 194 HRKYGPK-VDVWSIGVSMFAMLTGTLPFTVEPFNIKQLHQKMVIGEI---SPIPSDISPG 249
Query: 256 CKTVVKHLLEPDPGLRHSATNVLDSEWI 283
++ LLEPDP R + +W+
Sbjct: 250 AVHFMQSLLEPDPAKRPEVKEAMKDKWL 277
Score = 136 bits (328), Expect = 2e-30
Identities = 80/238 (33%), Positives = 126/238 (52%), Gaps = 7/238 (2%)
Query: 353 LACKVIDTSTAPRD-FVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
+A KVID A +D +V K + RE + + HP++V + + Y++ M GD
Sbjct: 44 VAIKVIDKRKAKQDSYVLKNMKREPRIHQMIKHPNVVQLYETLETDNSYYMVMELCLGGD 103
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
LL+ + + + E + R +TRQ+ A+ Y+H I HRD+K EN LL N N+K+ DFG
Sbjct: 104 LLDRICDKQRLAEREVRRYTRQILSAVGYLHCHGIVHRDLKIENFLLDENDNIKIVDFGL 163
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF-- 529
+ + L++ T CGS +Y APE+L Y PK DVWS+G+ ++ ML +PF
Sbjct: 164 SNTAKFEGLSQELLYTQCGSPAYAAPELLAHRKYGPK-VDVWSIGVSMFAMLTGTLPFTV 222
Query: 530 EDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
E +IKQLHQ + S IS + +LEP+ R ++ + + +W+
Sbjct: 223 EPFNIKQLHQKMVIGE---ISPIPSDISPGAVHFMQSLLEPDPAKRPEVKEAMKDKWL 277
>UniRef50_Q4RWR4 Cluster: Chromosome 15 SCAF14981, whole genome
shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 15
SCAF14981, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 411
Score = 143 bits (347), Expect = 1e-32
Identities = 79/265 (29%), Positives = 143/265 (53%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L +G G +++V + D K +A KI++ + + F E+ +V+L
Sbjct: 82 YELRGVIGSGNFSQVRFGIH----DLTKERVAVKILDKTRLEERSRDLF-NSEVACMVKL 136
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
HP+++ ++ + + + Y+ M Y GDL S I G +S+ ++++ Q+ ++++H
Sbjct: 137 AHPNVVCLYEMVETLERLYLVMEYASRGDLFSRISTRGRLSDLESKLVFSQVLSAVKHMH 196
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+ I HRD+K EN+ T+ + +K+ DFGFS FC +D L T+CGS+ YAAPE+ +
Sbjct: 197 DNNIVHRDLKAENIYYTSTYCIKVGDFGFSTFCSPAD----LLHTFCGSLPYAAPELFKQ 252
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
Y + DLW+LG++L+ M+ +MPF + L + Y + V + C+
Sbjct: 253 HRYKGRYVDLWALGILLYFMVTATMPFRASSTDGLQACILQGSYAIPNHV----PVSCQE 308
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
V+K LL+ P R + ++DS W+
Sbjct: 309 VIKGLLKQLPVDRLTVAQIMDSNWL 333
Score = 130 bits (314), Expect = 1e-28
Identities = 67/235 (28%), Positives = 125/235 (53%), Gaps = 9/235 (3%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++D T + + E+ ++KL+HP++V + + + + ++ M Y RGDL
Sbjct: 108 VAVKILD-KTRLEERSRDLFNSEVACMVKLAHPNVVCLYEMVETLERLYLVMEYASRGDL 166
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ RG + + ++++ Q+ A+++MH+ I HRD+K EN+ T+ +K+ DFGF+
Sbjct: 167 FSRISTRGRLSDLESKLVFSQVLSAVKHMHDNNIVHRDLKAENIYYTSTYCIKVGDFGFS 226
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
C L TFCGSL Y APE+ + Y + D+W+LGI++Y M+ MPF
Sbjct: 227 TFCSPADL----LHTFCGSLPYAAPELFKQHRYKGRYVDLWALGILLYFMVTATMPFRAS 282
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
L + ++ + + +C+ +I +L+ +RL + I++S W+
Sbjct: 283 STDGLQACILQGSYAIPNH----VPVSCQEVIKGLLKQLPVDRLTVAQIMDSNWL 333
>UniRef50_A2E0G9 Cluster: Protein kinase, putative; n=4; Trichomonas
vaginalis G3|Rep: Protein kinase, putative - Trichomonas
vaginalis G3
Length = 305
Score = 143 bits (347), Expect = 1e-32
Identities = 83/269 (30%), Positives = 145/269 (53%), Gaps = 11/269 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+ KF+G G+++ V+ ++ + +S +ACK+I+ A D V E+ + ++
Sbjct: 7 YEPHKFLGSGSFSGVWECQHMTTGES----VACKVIDINTAISDQVYYHFRNELLIHSKI 62
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+H + + I K YIF+ + GDL + G ++E +A+ + Q+ L Y+H
Sbjct: 63 HHSSITQLKDIIIDKDNIYIFIELCDGGDLNDIVQDVGGLTEQEAKHYFHQIIDALSYIH 122
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
+L +AHRD+K EN+L+TA+ + KL+DFG + + N P+L T CG++ YAAPEI+R
Sbjct: 123 KLGVAHRDVKLENILITADDDAKLTDFGLCK--QQRGNDPML--TTCGTLVYAAPEIIRE 178
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPF---DDTRMRKLYEQQMGKKYRFRSRVASILSLE 255
+PY D+WS G+VL+ M+ P+ DD L ++ + + +S E
Sbjct: 179 EPYNGMKADIWSAGIVLYAMIAAHFPWVVPDDLPPDILMKETAKQIASGDIILPDGISYE 238
Query: 256 CKTVVKHLLEPDPGLRHSATNVLDSEWIA 284
+ ++ ++L DP R +A +L W A
Sbjct: 239 LQNLLGNMLNVDPEERPTADEILQHPWFA 267
Score = 129 bits (311), Expect = 3e-28
Identities = 78/239 (32%), Positives = 124/239 (51%), Gaps = 7/239 (2%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+ACKVID +TA D V E+ + K+ H + I + +IF+ + GDL
Sbjct: 33 VACKVIDINTAISDQVYYHFRNELLIHSKIHHSSITQLKDIIIDKDNIYIFIELCDGGDL 92
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ V G + E +A+ + Q+ A+ Y+H+L +AHRD+K EN+L+TA+ + KL+DFG
Sbjct: 93 NDIVQDVGGLTEQEAKHYFHQIIDALSYIHKLGVAHRDVKLENILITADDDAKLTDFG-- 150
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF--E 530
+C ++ N+ T CG+L Y APEI++ PY D+WS GIV+Y M+ P+
Sbjct: 151 -LCKQQRGNDPMLTT-CGTLVYAAPEIIREEPYNGMKADIWSAGIVLYAMIAAHFPWVVP 208
Query: 531 DKHIKQLHQAQINKNWKFRSRYI-DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA 588
D + + K + D IS + L+G ML + + R +I+ W A
Sbjct: 209 DDLPPDILMKETAKQIASGDIILPDGISYELQNLLGNMLNVDPEERPTADEILQHPWFA 267
>UniRef50_UPI0000F2D863 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 553
Score = 143 bits (346), Expect = 2e-32
Identities = 87/283 (30%), Positives = 145/283 (51%), Gaps = 17/283 (6%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLP 69
E+ T+L + Y + +G+G++ V E + K K A K + KA VK L
Sbjct: 165 EDCTVLQQIYSFGRKLGQGSFGVVI--EVTDKITDTK--WAMKKVNKEKAGSS-AVKLLE 219
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
RE+ +L + H H+IH+ +F+ + Y+ M E G+L + K G SEN+ R +
Sbjct: 220 REVTILKTVKHEHIIHLERVFETAKRMYLVMELCEAGELKEMLSKKGHFSENETRQIIQD 279
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTA---------NFNVKLSDFGFSRFCVESDNQPVL 180
LA + YLH+ +I HRD+K EN+L+ + N+N+K++DFG + + +
Sbjct: 280 LASAIAYLHKKDIVHRDLKLENILVKSSYTNEENETNYNIKVTDFGLA--VQKEGGCESM 337
Query: 181 SETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGK 240
+T CG+ Y APE++ Y + D+WS+GV++++++ PF KL+E
Sbjct: 338 FQTTCGTPIYMAPEVINAHDY-SQQCDIWSIGVIMYMLICGEPPFIANSEEKLFELIRKG 396
Query: 241 KYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
K F +S K + LL+ DP R +A +LD++WI
Sbjct: 397 KLGFEKTAWERVSDSAKYALGQLLKVDPAHRITAKELLDNQWI 439
Score = 124 bits (298), Expect = 1e-26
Identities = 66/228 (28%), Positives = 125/228 (54%), Gaps = 14/228 (6%)
Query: 370 KFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARI 429
K L RE+ +L + H H++H +F+ + ++ M E G+L E + ++G E++ R
Sbjct: 216 KLLEREVTILKTVKHEHIIHLERVFETAKRMYLVMELCEAGELKEMLSKKGHFSENETRQ 275
Query: 430 WTRQLALAIQYMHELEIAHRDIKCENVLLTA---------NQNVKLSDFGFARMCVDKKL 480
+ LA AI Y+H+ +I HRD+K EN+L+ + N N+K++DFG A V K+
Sbjct: 276 IIQDLASAIAYLHKKDIVHRDLKLENILVKSSYTNEENETNYNIKVTDFGLA---VQKEG 332
Query: 481 N-EIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQ 539
E +T CG+ Y APE++ Y + D+WS+G+++Y+++ PF ++L +
Sbjct: 333 GCESMFQTTCGTPIYMAPEVINAHDY-SQQCDIWSIGVIMYMLICGEPPFIANSEEKLFE 391
Query: 540 AQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
F + +SD+ K +G +L+ + +R+ ++++++WI
Sbjct: 392 LIRKGKLGFEKTAWERVSDSAKYALGQLLKVDPAHRITAKELLDNQWI 439
>UniRef50_A7TRN0 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 1552
Score = 143 bits (346), Expect = 2e-32
Identities = 72/224 (32%), Positives = 128/224 (57%), Gaps = 10/224 (4%)
Query: 68 LPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWT 127
+ REI ++ L+HP+++ ++ +++ + Y+ + Y + G+L Y++ G ++E++A +
Sbjct: 182 IEREIVIMKLLSHPNVMALYEVWENNNELYLVLEYVDGGELFDYLVSKGKLTESEAVHYF 241
Query: 128 RQLALGLQYLHELEIAHRDIKCENVLLTANFN-VKLSDFGFSRFCVESDNQPVLSETYCG 186
+Q+ G+ Y H I HRD+K EN+LL +K++DFG + V + L +T CG
Sbjct: 242 KQIINGISYCHSFNICHRDLKPENLLLDKKRRIIKIADFGMAALQVSNR----LLQTSCG 297
Query: 187 SMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRS 246
S YA+PEI+ GK Y P+D+WS G++LF +L +PF+D ++KL + +Y
Sbjct: 298 SPHYASPEIVMGKCYNGAPSDIWSCGIILFALLTGHLPFNDDNIKKLLIKVQNGRY---- 353
Query: 247 RVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIA-MDSRL 289
++ S +S E K ++ +L DP R S +L + D RL
Sbjct: 354 QMPSYISQEAKNLISRILVVDPSKRISTEQILSHPLLTKYDKRL 397
Score = 127 bits (306), Expect = 1e-27
Identities = 69/224 (30%), Positives = 124/224 (55%), Gaps = 10/224 (4%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ REI ++ LSHP+++ + +++ + ++ + Y++ G+L ++++ +G + E +A +
Sbjct: 182 IEREIVIMKLLSHPNVMALYEVWENNNELYLVLEYVDGGELFDYLVSKGKLTESEAVHYF 241
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQN-VKLSDFGFARMCVDKKLNEIRSETFCG 490
+Q+ I Y H I HRD+K EN+LL + +K++DFG A + V +L +T CG
Sbjct: 242 KQIINGISYCHSFNICHRDLKPENLLLDKKRRIIKIADFGMAALQVSNRL----LQTSCG 297
Query: 491 SLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRS 550
S Y +PEI+ G Y P+D+WS GI+++ +L +PF D +IK+L N ++ S
Sbjct: 298 SPHYASPEIVMGKCYNGAPSDIWSCGIILFALLTGHLPFNDDNIKKLLIKVQNGRYQMPS 357
Query: 551 RYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIA-MDSRL 593
IS K LI +L + R+ I++ + D RL
Sbjct: 358 ----YISQEAKNLISRILVVDPSKRISTEQILSHPLLTKYDKRL 397
>UniRef50_Q8IY84 Cluster: Serine/threonine-protein kinase NIM1;
n=14; Eumetazoa|Rep: Serine/threonine-protein kinase
NIM1 - Homo sapiens (Human)
Length = 436
Score = 143 bits (346), Expect = 2e-32
Identities = 80/265 (30%), Positives = 145/265 (54%), Gaps = 13/265 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y++ +G G +++V L +S K +A KI++ K + + L REI + +L
Sbjct: 74 YRIRGEIGSGNFSQVKLGIHSLT----KEKVAIKILDKTKLDQK-TQRLLSREISSMEKL 128
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP++I ++ + + +K ++ M Y G+L I G +SE ++++ Q+ ++++H
Sbjct: 129 HHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMH 188
Query: 139 ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRG 198
E +I HRD+K ENV T+N VK+ DFGFS + + + T+CGS YAAPE+ R
Sbjct: 189 ENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGE----MLNTFCGSPPYAAPELFRD 244
Query: 199 KPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKT 258
+ Y D+W+LGV+L+ M+ +MPF + KL + + Y V +S C
Sbjct: 245 EHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTY----SVPPHVSEPCHR 300
Query: 259 VVKHLLEPDPGLRHSATNVLDSEWI 283
+++ +L+ P R+ +++ EW+
Sbjct: 301 LIRGVLQQIPTERYGIDCIMNDEWM 325
Score = 138 bits (333), Expect = 6e-31
Identities = 81/272 (29%), Positives = 143/272 (52%), Gaps = 14/272 (5%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K++D + + ++ L REI + KL HP+++ + + + K + M Y G+L
Sbjct: 100 VAIKILDKTKLDQK-TQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGEL 158
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ G + E ++++ Q+ A+++MHE +I HRD+K ENV T+N VK+ DFGF+
Sbjct: 159 FGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFS 218
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
V KK + TFCGS Y APE+ + Y+ D+W+LG+++Y M+ MPF +
Sbjct: 219 --TVSKKGEML--NTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAE 274
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW---IAM 589
+ +L ++ + + +S+ C RLI +L+ R I I+N EW +
Sbjct: 275 TVAKLKKSILEGTYSVPPH----VSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQGVPY 330
Query: 590 DSRL--LEWTPQETLAYKKAREEKNKLHKTVE 619
+ L + P+ +EE+N++ T+E
Sbjct: 331 PTPLEPFQLDPKHLSETSTLKEEENEVKSTLE 362
>UniRef50_P13185 Cluster: Protein kinase KIN1; n=2; Saccharomyces
cerevisiae|Rep: Protein kinase KIN1 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 1064
Score = 143 bits (346), Expect = 2e-32
Identities = 74/214 (34%), Positives = 118/214 (55%), Gaps = 8/214 (3%)
Query: 70 REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQ 129
RE + L HPH+ + + +Y+ Y G LL YI+++G + E+QAR + R
Sbjct: 193 REASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARG 252
Query: 130 LALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMS 189
+A L YLH I HRD+K EN++++ + +K+ DFG S D++ L T+CGS+
Sbjct: 253 IASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNI---YDSRKQL-HTFCGSLY 308
Query: 190 YAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVA 249
+AAPE+L+ PY D+WS GVVLFV++ +PFDD L+E+ K +
Sbjct: 309 FAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQH-- 366
Query: 250 SILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
LS+E +++ +L DP R + V++ W+
Sbjct: 367 --LSIEVISLLSKMLVVDPKRRATLKQVVEHHWM 398
Score = 133 bits (322), Expect = 1e-29
Identities = 66/214 (30%), Positives = 118/214 (55%), Gaps = 8/214 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE + L HPH+ + +++ Y+ G LL++++Q G+++E QAR + R
Sbjct: 193 REASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARG 252
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+A A+ Y+H I HRD+K EN++++ + +K+ DFG + + +K + TFCGSL
Sbjct: 253 IASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFGLSNIYDSRK----QLHTFCGSLY 308
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
+ APE+L+ PY DVWS G+V++V++ +PF+D++ LH+ K + + Y
Sbjct: 309 FAAPELLKANPYTGPEVDVWSFGVVLFVLVCGKVPFDDENSSVLHE----KIKQGKVEYP 364
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+S L+ ML + + R + +V W+
Sbjct: 365 QHLSIEVISLLSKMLVVDPKRRATLKQVVEHHWM 398
>UniRef50_UPI000049857F Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 424
Score = 142 bits (345), Expect = 2e-32
Identities = 80/251 (31%), Positives = 132/251 (52%), Gaps = 9/251 (3%)
Query: 71 EIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQL 130
E ++L RL+HP++I + ++Q Y+ + G+L I+ +E + R+ RQ+
Sbjct: 173 ECEILKRLDHPNIIKLKEVYQTTKYLYMVIELVTGGELFDQIVAETHFTEAKCRIIIRQI 232
Query: 131 ALGLQYLHELEIAHRDIKCENVLL--TANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
L+YLH I HRD+K EN+L +K++DFG SR N L++T CG+
Sbjct: 233 FSALEYLHSQNIIHRDLKPENILCVKAGTDEIKITDFGLSRII----NPETLAKTMCGTP 288
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPF---DDTRMRKLYEQQMGKKYRFR 245
Y +PEIL GKPY D+WS GVVL+VM PF ++ R L++ + K+ FR
Sbjct: 289 LYVSPEILSGKPYNGSKVDVWSTGVVLYVMACGFPPFVEGENDGNRMLFDNILAGKFEFR 348
Query: 246 SRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVEAAALKRAKE 305
S SLE K ++KH+L DP R+S + ++ ++ M L + + +
Sbjct: 349 SPFWDNKSLELKDLIKHMLVVDPEERYSIEDCVNHPFMKMKISDEQLKRTVSDIVMEEPK 408
Query: 306 DRRKLSDVHKH 316
D++ + ++ K+
Sbjct: 409 DKKGIEELSKY 419
Score = 120 bits (289), Expect = 1e-25
Identities = 71/220 (32%), Positives = 115/220 (52%), Gaps = 9/220 (4%)
Query: 375 EIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQL 434
E E+L +L HP+++ ++Q ++ + + G+L + ++ E + RI RQ+
Sbjct: 173 ECEILKRLDHPNIIKLKEVYQTTKYLYMVIELVTGGELFDQIVAETHFTEAKCRIIIRQI 232
Query: 435 ALAIQYMHELEIAHRDIKCENVLL--TANQNVKLSDFGFARMCVDKKLNEIRSETFCGSL 492
A++Y+H I HRD+K EN+L +K++DFG +R+ + L ++T CG+
Sbjct: 233 FSALEYLHSQNIIHRDLKPENILCVKAGTDEIKITDFGLSRIINPETL----AKTMCGTP 288
Query: 493 SYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF---EDKHIKQLHQAQINKNWKFR 549
Y +PEIL G PY DVWS G+V+YVM PF E+ + L + ++FR
Sbjct: 289 LYVSPEILSGKPYNGSKVDVWSTGVVLYVMACGFPPFVEGENDGNRMLFDNILAGKFEFR 348
Query: 550 SRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAM 589
S + D S K LI ML + + R I D VN ++ M
Sbjct: 349 SPFWDNKSLELKDLIKHMLVVDPEERYSIEDCVNHPFMKM 388
>UniRef50_Q960G5 Cluster: SD02969p; n=4; Sophophora|Rep: SD02969p -
Drosophila melanogaster (Fruit fly)
Length = 860
Score = 142 bits (345), Expect = 2e-32
Identities = 83/267 (31%), Positives = 139/267 (52%), Gaps = 15/267 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y L + +G G +A V L + + +A K+++ K D L +E+ + +
Sbjct: 20 YDLEETLGSGHFAVVKLARHVFTG----AKVAVKVVDKTKLD-DVSKAHLFQEVRCMKLV 74
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGC-VSENQARVWTRQLALGLQYL 137
HP+++ ++ + +TK Y+ + + GDL YI+K+ +SE AR + RQ+ + Y
Sbjct: 75 QHPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYC 134
Query: 138 HELEIAHRDIKCENVLLTANFN-VKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEIL 196
H+L + HRD+K ENV+ VKL+DFGFS + ET+CGS++Y+APEIL
Sbjct: 135 HQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQKL----ETFCGSLAYSAPEIL 190
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLEC 256
G Y D+WSLGV+L++++ PF+ + M KY V S +S +C
Sbjct: 191 LGDSYDAPAVDIWSLGVILYMLVCGQAPFEKANDSETLTMIMDCKY----TVPSHVSTDC 246
Query: 257 KTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ ++ +L DP R + + S W+
Sbjct: 247 RDLIASMLVRDPKKRATVEEIASSAWL 273
Score = 135 bits (326), Expect = 4e-30
Identities = 77/237 (32%), Positives = 133/237 (56%), Gaps = 11/237 (4%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A KV+D T D K L +E+ + + HP++V + + + K ++ + + GDL
Sbjct: 46 VAVKVVD-KTKLDDVSKAHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLVLELGDGGDL 104
Query: 413 LEFVLQRGA-VQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQN-VKLSDFG 470
+++++ + + E+ AR + RQ+ AI Y H+L + HRD+K ENV+ VKL+DFG
Sbjct: 105 YDYIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFG 164
Query: 471 FARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFE 530
F+ +K L + ETFCGSL+Y+APEIL G Y D+WSLG+++Y+++ PFE
Sbjct: 165 FS----NKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPFE 220
Query: 531 DKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
+ + ++ + S +S +C+ LI ML + + R + +I +S W+
Sbjct: 221 KANDSETLTMIMDCKYTVPSH----VSTDCRDLIASMLVRDPKKRATVEEIASSAWL 273
>UniRef50_A2DWE7 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 439
Score = 142 bits (345), Expect = 2e-32
Identities = 82/270 (30%), Positives = 140/270 (51%), Gaps = 15/270 (5%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y+L +GEG++A V+ + A K + V + REI ++ L
Sbjct: 9 YELFDKIGEGSFAFVW----EGRNTITNCPCAVKQFRKDTFNHEAAVS-MNREISIMQIL 63
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP + ++ + + + ++FM +NG LL YI KN +SEN++R+ Q+ L YLH
Sbjct: 64 DHPLIAQLYEVVETQHDTFLFMELVDNGTLLEYINKNAPISENKSRIIFAQIVAVLDYLH 123
Query: 139 -ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
E + HRD+K EN+L+ N N+++ DFG S NQ + T CGS +Y APE+L
Sbjct: 124 NEKRVVHRDLKAENILIDQNDNIRVIDFGLSNVL----NQNTVLYTACGSSAYVAPEMLL 179
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
KPY + D+WS GV+L+ M +PF+D+ + +L ++ + ++ + + L+
Sbjct: 180 NKPY-TQAADIWSAGVLLYAMNAAHLPFEDSNVTRLVDKVLNRQPEYPLAFSKNLT---- 234
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWIAMDS 287
++ +L DP R + +L W D+
Sbjct: 235 ELISKMLTKDPSQRITLEGILHDPWFLSDA 264
Score = 131 bits (316), Expect = 7e-29
Identities = 66/219 (30%), Positives = 117/219 (53%), Gaps = 10/219 (4%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
REI ++ L HP + + + + ++ F+FM ++ G LLE++ + + E+++RI Q
Sbjct: 55 REISIMQILDHPLIAQLYEVVETQHDTFLFMELVDNGTLLEYINKNAPISENKSRIIFAQ 114
Query: 434 LALAIQYMH-ELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSL 492
+ + Y+H E + HRD+K EN+L+ N N+++ DFG + + + T CGS
Sbjct: 115 IVAVLDYLHNEKRVVHRDLKAENILIDQNDNIRVIDFGLSNVLNQNTV----LYTACGSS 170
Query: 493 SYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRY 552
+Y APE+L PY + D+WS G+++Y M +PFED ++ +L +N+ + Y
Sbjct: 171 AYVAPEMLLNKPY-TQAADIWSAGVLLYAMNAAHLPFEDSNVTRLVDKVLNR----QPEY 225
Query: 553 IDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDS 591
S N LI ML + R+ + I++ W D+
Sbjct: 226 PLAFSKNLTELISKMLTKDPSQRITLEGILHDPWFLSDA 264
>UniRef50_Q75CE9 Cluster: ACR142Wp; n=1; Eremothecium gossypii|Rep:
ACR142Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 837
Score = 142 bits (345), Expect = 2e-32
Identities = 95/322 (29%), Positives = 165/322 (51%), Gaps = 26/322 (8%)
Query: 2 TDLKT-TPSEENTLLTKGYKLT-KFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKA 59
T L+T +P T + K + + + VG+GA+A V + E + T A KII K
Sbjct: 198 TTLRTQSPRAPLTGIFKDFSINDEVVGQGAFATVK----KAVERNTGKTFAVKIINKRKV 253
Query: 60 PKDFVVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVS 119
+ V + RE++VL RLNHP ++ + ++ YY+ M + GDL+ ++ +G V
Sbjct: 254 MGN--VDGVTRELEVLRRLNHPRIVSLKGFYEDDESYYLLMEFVSGGDLMDFVAAHGSVG 311
Query: 120 ENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTAN--FNVKLSDFGFSRFCVESDNQ 177
E+ R TRQ+ ++Y+HE I+HRD+K +N+L+ + VK++DFG ++ DN
Sbjct: 312 EDAGREITRQILEAVRYIHEQGISHRDLKPDNILIEQDDPVLVKITDFGLAKI---QDNT 368
Query: 178 PVLSETYCGSMSYAAPEILRGK---------PYCPKPTDLWSLGVVLFVMLNKSMPFDDT 228
+ +T+CG+++Y APE++ GK D+WS+G +++V+L +PF +
Sbjct: 369 TFM-KTFCGTLAYVAPEVIGGKNPEGNGANGNLYSSLVDMWSIGCLVYVILTGHLPFSGS 427
Query: 229 RMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSR 288
+LY+Q Y +S E + + LL+ +P R +A L W+
Sbjct: 428 TQEQLYKQIANGSYHEGPLKDYWISDEARDFIDSLLQINPVDRLTAERALQHPWL---HP 484
Query: 289 LTTLNAVEAAALKRAKEDRRKL 310
T++ A A +L ++ R L
Sbjct: 485 CTSIGAEIAVSLSQSLSQARAL 506
Score = 133 bits (322), Expect = 1e-29
Identities = 86/288 (29%), Positives = 151/288 (52%), Gaps = 21/288 (7%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE+E+L +L+HP +V ++ Y++ M ++ GDL++FV G+V ED R TRQ
Sbjct: 262 RELEVLRRLNHPRIVSLKGFYEDDESYYLLMEFVSGGDLMDFVAAHGSVGEDAGREITRQ 321
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQN--VKLSDFGFARMCVDKKLNEIRSETFCGS 491
+ A++Y+HE I+HRD+K +N+L+ + VK++DFG A++ + N +TFCG+
Sbjct: 322 ILEAVRYIHEQGISHRDLKPDNILIEQDDPVLVKITDFGLAKI----QDNTTFMKTFCGT 377
Query: 492 LSYTAPEILQG-TP--------YLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQI 542
L+Y APE++ G P D+WS+G +VYV+L +PF +QL++
Sbjct: 378 LAYVAPEVIGGKNPEGNGANGNLYSSLVDMWSIGCLVYVILTGHLPFSGSTQEQLYKQIA 437
Query: 543 NKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRL---LEWTPQ 599
N ++ ISD + I +L+ N +RL + W+ + + + +
Sbjct: 438 NGSYHEGPLKDYWISDEARDFIDSLLQINPVDRLTAERALQHPWLHPCTSIGAEIAVSLS 497
Query: 600 ETLAYKKAREEKNKLHKTVETVELPGSSKT---EHKVCLPDSLVENNL 644
++L+ +A E ++ V E+ + K E +V L D + E N+
Sbjct: 498 QSLSQARALEGMDEAEYLVAQSEVASNRKAPTHEKRVILADHIAEENV 545
>UniRef50_Q5K995 Cluster: Protein kinase kin1, putative; n=2;
Filobasidiella neoformans|Rep: Protein kinase kin1,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 1005
Score = 142 bits (345), Expect = 2e-32
Identities = 90/286 (31%), Positives = 146/286 (51%), Gaps = 23/286 (8%)
Query: 8 PSEENTLLTKGYKLTKFVGEGAYAKVYL-TEYSSKEDSH-----KSTLACKIIETAKAPK 61
P + + ++L K +G G+ KV L T +KE + T A + ET + P+
Sbjct: 129 PKKSKVRMVGDWQLNKTLGAGSMGKVKLATNIVTKEKCAVKIIPRYTDANRKEETTRTPE 188
Query: 62 DFVVKFLP---------REIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYI 112
+ + L RE + + L+HP++ + + +Y+ + + G +L YI
Sbjct: 189 EVEKQRLKDESKEIRTIREAHISLLLHHPYICGMREFISHQNHHYMVFEFIDGGQMLDYI 248
Query: 113 LKNGCVSENQARVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCV 172
+ +G + E AR + RQ+ L Y H+ I HRD+K EN+L++ N N+KL DFG S
Sbjct: 249 ISHGRLRERAARKFARQIGSALNYCHQNSIVHRDLKIENILISKNGNIKLIDFGLSNLYS 308
Query: 173 ESDNQPVLSETYCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRK 232
S + LS T+CGS+ +AAPE+L +PY D+WS G+V++V++ +PFDD M
Sbjct: 309 PSRH---LS-TFCGSLYFAAPELLNARPYTGPEVDVWSFGIVIYVLVCGKVPFDDQSMPA 364
Query: 233 LYEQQMGKKYRFRSRVASILSLECKTVVKHLLEPDPGLRHSATNVL 278
L+ K R S LS E K+++ +L +P R + VL
Sbjct: 365 LH----AKIKRGVVEYPSWLSAEVKSLLSRMLVTNPAERATLAEVL 406
Score = 136 bits (328), Expect = 2e-30
Identities = 67/210 (31%), Positives = 115/210 (54%), Gaps = 8/210 (3%)
Query: 374 REIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQ 433
RE + + L HP++ + +++ +++ G +L++++ G ++E AR + RQ
Sbjct: 206 REAHISLLLHHPYICGMREFISHQNHHYMVFEFIDGGQMLDYIISHGRLRERAARKFARQ 265
Query: 434 LALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLS 493
+ A+ Y H+ I HRD+K EN+L++ N N+KL DFG + + + TFCGSL
Sbjct: 266 IGSALNYCHQNSIVHRDLKIENILISKNGNIKLIDFGLSNLYSPSR----HLSTFCGSLY 321
Query: 494 YTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYI 553
+ APE+L PY DVWS GIV+YV++ +PF+D+ + LH A+I + Y
Sbjct: 322 FAAPELLNARPYTGPEVDVWSFGIVIYVLVCGKVPFDDQSMPALH-AKIKRG---VVEYP 377
Query: 554 DTISDNCKRLIGLMLEPNHQNRLKIYDIVN 583
+S K L+ ML N R + ++++
Sbjct: 378 SWLSAEVKSLLSRMLVTNPAERATLAEVLS 407
>UniRef50_UPI00006D00D8 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 692
Score = 142 bits (344), Expect = 3e-32
Identities = 76/245 (31%), Positives = 122/245 (49%), Gaps = 15/245 (6%)
Query: 24 FVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHL 83
F + + ++ +K D +A KII K + + REI +L NH ++
Sbjct: 64 FSKKSEFKNIFCFIIVAKHDITGKEVAIKIINKKKMTVKKMSNKIKREIRLLRFFNHQNI 123
Query: 84 IHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIA 143
I ++ + T ++ Y GDL I G + E +A+ + +Q+ G+ Y H +A
Sbjct: 124 IRLYEVLDTNTDIFVVTEYISGGDLYDVIASKGKLPEQEAKRYFKQIVAGVDYCHRNLVA 183
Query: 144 HRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCP 203
HRD+K EN+L+ N N+K++DFG S N T CGS +YAAPE++ GK YC
Sbjct: 184 HRDLKLENILIDDNNNIKIADFGLSNIM----NDGKYLSTSCGSPNYAAPEVISGKLYCG 239
Query: 204 KPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECKTVVKHL 263
D WS GV+LF +L +PFD+ + LY+ ++ + S E ++K +
Sbjct: 240 TEVDTWSCGVILFALLGGYLPFDEEVIPALYK-----------KIKAFFSPEAHDIIKRM 288
Query: 264 LEPDP 268
L P+P
Sbjct: 289 LRPNP 293
Score = 127 bits (306), Expect = 1e-27
Identities = 65/235 (27%), Positives = 120/235 (51%), Gaps = 15/235 (6%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I+ + + REI +L +H +++ + + F+ Y+ GDL
Sbjct: 89 VAIKIINKKKMTVKKMSNKIKREIRLLRFFNHQNIIRLYEVLDTNTDIFVVTEYISGGDL 148
Query: 413 LEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFA 472
+ + +G + E +A+ + +Q+ + Y H +AHRD+K EN+L+ N N+K++DFG +
Sbjct: 149 YDVIASKGKLPEQEAKRYFKQIVAGVDYCHRNLVAHRDLKLENILIDDNNNIKIADFGLS 208
Query: 473 RMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDK 532
+ D K T CGS +Y APE++ G Y D WS G++++ +L +PF+++
Sbjct: 209 NIMNDGKY----LSTSCGSPNYAAPEVISGKLYCGTEVDTWSCGVILFALLGGYLPFDEE 264
Query: 533 HIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWI 587
I L++ K ++ + D KR ML PN R+K +++ W+
Sbjct: 265 VIPALYK-------KIKAFFSPEAHDIIKR----MLRPNPIERIKFHELRLHPWL 308
>UniRef50_A2EFB7 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 396
Score = 142 bits (344), Expect = 3e-32
Identities = 78/267 (29%), Positives = 138/267 (51%), Gaps = 13/267 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKF-LPREIDVLVR 77
Y + +G GA++ V L ++ K ACKII+ KD + E +L +
Sbjct: 14 YTFKQTLGHGAFSVVKLAIHNVT----KQQFACKIIKKTALSKDNKAEERFELETRILQQ 69
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
+ HP++ + I T +Y+ + NG+L +I++N + EN+A+++ + + L+Y+
Sbjct: 70 MRHPNIAQLFDIMADGTFFYVVLEICPNGELFKFIIQNKFLPENEAKMYMKPIVEALKYI 129
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
H+L++ HRD+K EN+LL K++DFGFSR+ + L +T CGS YA+P +
Sbjct: 130 HDLKVVHRDLKPENILLDDKNRPKITDFGFSRYVLHDQ----LLKTTCGSPCYASPACIA 185
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
GK Y D+W LGV+ F + +P+ +L+EQ +Y + S +S + +
Sbjct: 186 GKEYDGFKNDIWGLGVIFFATVTGQLPWTKKIESELFEQISRAEY----TIPSYISDDLR 241
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEWIA 284
++ ++ D R + +L S W A
Sbjct: 242 ELISSMMNIDESKRPTCDQILASPWFA 268
Score = 117 bits (281), Expect = 1e-24
Identities = 69/257 (26%), Positives = 128/257 (49%), Gaps = 13/257 (5%)
Query: 333 AFRVYLAEYRNASKNDKLSILACKVIDTSTAPRDF-VKKFLPREIEMLIKLSHPHLVHTH 391
AF V N +K ACK+I + +D ++ E +L ++ HP++
Sbjct: 24 AFSVVKLAIHNVTKQQ----FACKIIKKTALSKDNKAEERFELETRILQQMRHPNIAQLF 79
Query: 392 SIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDI 451
I +++ + G+L +F++Q + E++A+++ + + A++Y+H+L++ HRD+
Sbjct: 80 DIMADGTFFYVVLEICPNGELFKFIIQNKFLPENEAKMYMKPIVEALKYIHDLKVVHRDL 139
Query: 452 KCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTD 511
K EN+LL K++DFGF+R + +L +T CGS Y +P + G Y D
Sbjct: 140 KPENILLDDKNRPKITDFGFSRYVLHDQL----LKTTCGSPCYASPACIAGKEYDGFKND 195
Query: 512 VWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPN 571
+W LG++ + + +P+ K +L + QI++ Y ISD+ + LI M+ +
Sbjct: 196 IWGLGVIFFATVTGQLPWTKKIESELFE-QISRAEYTIPSY---ISDDLRELISSMMNID 251
Query: 572 HQNRLKIYDIVNSEWIA 588
R I+ S W A
Sbjct: 252 ESKRPTCDQILASPWFA 268
>UniRef50_Q6BTQ3 Cluster: Similar to CA2348|IPF12811 Candida
albicans; n=1; Debaryomyces hansenii|Rep: Similar to
CA2348|IPF12811 Candida albicans - Debaryomyces hansenii
(Yeast) (Torulaspora hansenii)
Length = 979
Score = 142 bits (344), Expect = 3e-32
Identities = 89/271 (32%), Positives = 141/271 (52%), Gaps = 11/271 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKF-LPREIDVLVR 77
Y L +GEG + KV L K+ H S +A K+I+ KD + + REI+ L
Sbjct: 37 YILGSTLGEGEFGKVKLGW--RKDGKHPSQVAIKLIKRDTIMKDSESEIKIHREINSLKM 94
Query: 78 LNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYL 137
LNHP+++++ + + I + Y G+L YIL++ + EN A+ QL G+ Y+
Sbjct: 95 LNHPNIVNLVEVMKSGKYIGIVLEYASGGELFDYILQHKYLKENVAKKLFAQLVSGVDYM 154
Query: 138 HELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPE-IL 196
H + HRD+K EN+LL + NV +SDFGF + N L +T CGS YAAPE +L
Sbjct: 155 HSKGLIHRDLKLENLLLDKHKNVIISDFGFVNSYNKDKND--LMKTSCGSPCYAAPELVL 212
Query: 197 RGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV----ASIL 252
PY + D WSLGV+L+ ML +PFDD + + + Y + + +
Sbjct: 213 TQAPYEGRKVDTWSLGVILYAMLAGYLPFDDDPENE-DGSDIVRLYHYICKTPLTFPEYI 271
Query: 253 SLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
S + +++ ++ PDP R + N+ + W+
Sbjct: 272 SPLARDLLRKIIVPDPKKRITIKNIKNHPWL 302
Score = 127 bits (307), Expect = 8e-28
Identities = 95/323 (29%), Positives = 160/323 (49%), Gaps = 15/323 (4%)
Query: 285 MDSRLTTLNAVEAAALKRAKEDRRKLSDVHKHPPKRQGDILEGPTR-ESAFRVYLAEYRN 343
M S++ T N E +A + + +H+ R G + G T E F +R
Sbjct: 1 MSSQVVT-NLEETTNQHKAINNPNVVKRIHREV--RFGLYILGSTLGEGEFGKVKLGWRK 57
Query: 344 ASKNDKLSILACKVIDTSTAPRDFVKKF-LPREIEMLIKLSHPHLVHTHSIFQRRYKYFI 402
K+ S +A K+I T +D + + REI L L+HP++V+ + + I
Sbjct: 58 DGKHP--SQVAIKLIKRDTIMKDSESEIKIHREINSLKMLNHPNIVNLVEVMKSGKYIGI 115
Query: 403 FMRYMERGDLLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQ 462
+ Y G+L +++LQ ++E+ A+ QL + YMH + HRD+K EN+LL ++
Sbjct: 116 VLEYASGGELFDYILQHKYLKENVAKKLFAQLVSGVDYMHSKGLIHRDLKLENLLLDKHK 175
Query: 463 NVKLSDFGFARMCVDKKLNEIRSETFCGSLSYTAPE-ILQGTPYLPKPTDVWSLGIVVYV 521
NV +SDFGF +K N++ +T CGS Y APE +L PY + D WSLG+++Y
Sbjct: 176 NVIISDFGFVN-SYNKDKNDL-MKTSCGSPCYAAPELVLTQAPYEGRKVDTWSLGVILYA 233
Query: 522 MLNRAMPFEDKHIKQLHQAQINKNWKFRSR----YIDTISDNCKRLIGLMLEPNHQNRLK 577
ML +PF+D + + I + + + + + + IS + L+ ++ P+ + R+
Sbjct: 234 MLAGYLPFDDDPENE-DGSDIVRLYHYICKTPLTFPEYISPLARDLLRKIIVPDPKKRIT 292
Query: 578 IYDIVNSEWIAMDSRLLEWTPQE 600
I +I N W+ LL T E
Sbjct: 293 IKNIKNHPWLTPYVNLLSVTQPE 315
>UniRef50_Q4P2M4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1647
Score = 142 bits (344), Expect = 3e-32
Identities = 94/311 (30%), Positives = 156/311 (50%), Gaps = 21/311 (6%)
Query: 9 SEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFL 68
S + Y L + +GEG + KV L + + +A K I A + L
Sbjct: 39 SSSKLKIVGNYTLQRPIGEGTFGKVRLGLHRLTN----TRVAIKQIPKAHSAS------L 88
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTR 128
REI RL+HP+++ ++ + + ++ G+L Y+++N ++E +AR
Sbjct: 89 TREIHHHRRLHHPNVMQLYEVIATEQYIWMVSELCAGGELYDYLVENQVLAEPEARRIFG 148
Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
QL L + Y+H I HRD+K EN+LL NVKL DFGF+R E + L +T+CG+
Sbjct: 149 QLCLAVAYVHSKGIVHRDLKLENILLDERCNVKLGDFGFTR---EFERNR-LMDTFCGTT 204
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRV 248
YA+PE+L GK Y + D+WSLGV+L+ +L ++PFDD + ++ + + +
Sbjct: 205 GYASPEMLAGKKYTGEQVDIWSLGVILYALLCGALPFDDDDEAVMKQKILQGDF----EI 260
Query: 249 ASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW---IAMDSRLTTLNAVEAAALKRAKE 305
LS E +V +L+ DP R S ++L W + ++S ++TL + A A +
Sbjct: 261 PDCLSEEAHDLVVSILQHDPAKRPSIQSILAHPWFTKMMVNSPMSTLEEDQIATDYFASK 320
Query: 306 DRRKLSDVHKH 316
S +H
Sbjct: 321 PSASTSQSKQH 331
Score = 125 bits (302), Expect = 3e-27
Identities = 70/231 (30%), Positives = 120/231 (51%), Gaps = 11/231 (4%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
L REI +L HP+++ + + ++ G+L +++++ + E +AR
Sbjct: 88 LTREIHHHRRLHHPNVMQLYEVIATEQYIWMVSELCAGGELYDYLVENQVLAEPEARRIF 147
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
QL LA+ Y+H I HRD+K EN+LL NVKL DFGF R +L +TFCG+
Sbjct: 148 GQLCLAVAYVHSKGIVHRDLKLENILLDERCNVKLGDFGFTREFERNRL----MDTFCGT 203
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y +PE+L G Y + D+WSLG+++Y +L A+PF+D + Q + +++
Sbjct: 204 TGYASPEMLAGKKYTGEQVDIWSLGVILYALLCGALPFDDDDEAVMKQKILQGDFEIP-- 261
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLLEWTPQETL 602
D +S+ L+ +L+ + R I I+ W ++++ +P TL
Sbjct: 262 --DCLSEEAHDLVVSILQHDPAKRPSIQSILAHPWF---TKMMVNSPMSTL 307
>UniRef50_Q98SC8 Cluster: SNF1-related protein kinase; n=1;
Guillardia theta|Rep: SNF1-related protein kinase -
Guillardia theta (Cryptomonas phi)
Length = 401
Score = 142 bits (343), Expect = 4e-32
Identities = 79/277 (28%), Positives = 144/277 (51%), Gaps = 17/277 (6%)
Query: 10 EENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKA-PKDFVVKFL 68
E N Y L K +G GA KV L ++S K + KII+ K + +
Sbjct: 6 EYNIRFVGSYILDKTLGVGATGKVKLAKHSRT----KEKVGVKIIKKDLFYDKPSLRLKI 61
Query: 69 PREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTR 128
REI V+ + HPH+I ++ + + ++ + Y G+L +Y+++ + +A +
Sbjct: 62 QREISVMKLMFHPHVIKIYDVLEDSKYLFLIIEYASKGELFNYLVEKRKLENREALKFFH 121
Query: 129 QLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSM 188
++ GL+Y H+ I HRD+K EN+LL +K++DFG + + + ++ +T+CGS
Sbjct: 122 EIISGLEYCHKHRICHRDLKLENILLDMKLQIKIADFGMASLSIPN----IMLKTFCGSP 177
Query: 189 SYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDD--TRMRKLYEQQMGKKYRFR- 245
YA+PE++ +PY D+WS G++L+ ++ +P+D+ MRKL+ K RF
Sbjct: 178 HYASPEVVSNEPYNGIKADIWSCGIILYALVVGKLPYDEENDNMRKLF-----NKIRFEP 232
Query: 246 SRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEW 282
R+ I+ +C+ +++ LL +P R + + W
Sbjct: 233 PRIPRIIHPDCRDLIRALLTINPQKRITIDKIKKHPW 269
Score = 121 bits (291), Expect = 7e-26
Identities = 59/215 (27%), Positives = 113/215 (52%), Gaps = 6/215 (2%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
+ REI ++ + HPH++ + + + F+ + Y +G+L +++++ ++ +A +
Sbjct: 61 IQREISVMKLMFHPHVIKIYDVLEDSKYLFLIIEYASKGELFNYLVEKRKLENREALKFF 120
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
++ ++Y H+ I HRD+K EN+LL +K++DFG A + + I +TFCGS
Sbjct: 121 HEIISGLEYCHKHRICHRDLKLENILLDMKLQIKIADFGMASLSIP----NIMLKTFCGS 176
Query: 492 LSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFRSR 551
Y +PE++ PY D+WS GI++Y ++ +P+++++ + NK R
Sbjct: 177 PHYASPEVVSNEPYNGIKADIWSCGIILYALVVGKLPYDEENDNM--RKLFNKIRFEPPR 234
Query: 552 YIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
I +C+ LI +L N Q R+ I I W
Sbjct: 235 IPRIIHPDCRDLIRALLTINPQKRITIDKIKKHPW 269
>UniRef50_Q3I4W2 Cluster: Putative serine/threonine protein kinase;
n=1; Moneuplotes crassus|Rep: Putative serine/threonine
protein kinase - Euplotes crassus
Length = 503
Score = 142 bits (343), Expect = 4e-32
Identities = 84/280 (30%), Positives = 149/280 (53%), Gaps = 13/280 (4%)
Query: 4 LKTTPSEENTLLTKGYKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDF 63
++ T E T +K Y++ K +G+GA+ KV L + + +A K I ++
Sbjct: 4 IEETGKEPETK-SKHYRVGKLLGKGAFGKVSLGMHKATNQ----LVAIKSINKEFLEEER 58
Query: 64 VVKFLPREIDVLVRLNHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQA 123
K + RE+ +L +L H ++I+++ F+ + + + GDLL+Y+ + ++E A
Sbjct: 59 SRKKVAREVAILKKLQHSNIINLYETFETEKHFLLVTELCPGGDLLNYVRRRRKLTEETA 118
Query: 124 RVWTRQLALGLQYLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSET 183
+ + +QL Y H+ + HRDIK +N+LL +KL DFG SR +++ + +
Sbjct: 119 KYFFKQLVEACIYCHKKGVVHRDIKLDNILLDQKGCLKLGDFGVSRAIKKNE----ILKD 174
Query: 184 YCGSMSYAAPEILRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYR 243
CG+ +Y APE+L + Y K +D WS GVVLF ML ++PF T M +L+ +Y
Sbjct: 175 QCGTPAYIAPEVLHNRGYNGKLSDTWSCGVVLFAMLYGTVPFKGTNMDELHSLIKNGQYS 234
Query: 244 FRSRVASILSLECKTVVKHLLEPDPGLRHSATNVLDSEWI 283
+ V S E + ++K +LE +P R + +L++ W+
Sbjct: 235 LKDSV----SKEGRKLIKGILEINPKKRLTLKEILETPWL 270
Score = 137 bits (332), Expect = 8e-31
Identities = 81/256 (31%), Positives = 140/256 (54%), Gaps = 9/256 (3%)
Query: 352 ILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGD 411
++A K I+ + +K + RE+ +L KL H ++++ + F+ + + GD
Sbjct: 43 LVAIKSINKEFLEEERSRKKVAREVAILKKLQHSNIINLYETFETEKHFLLVTELCPGGD 102
Query: 412 LLEFVLQRGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGF 471
LL +V +R + E+ A+ + +QL A Y H+ + HRDIK +N+LL +KL DFG
Sbjct: 103 LLNYVRRRRKLTEETAKYFFKQLVEACIYCHKKGVVHRDIKLDNILLDQKGCLKLGDFGV 162
Query: 472 ARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPFED 531
+R K NEI + CG+ +Y APE+L Y K +D WS G+V++ ML +PF+
Sbjct: 163 SRAI---KKNEILKDQ-CGTPAYIAPEVLHNRGYNGKLSDTWSCGVVLFAMLYGTVPFKG 218
Query: 532 KHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDS 591
++ +LH + KN ++ + D++S ++LI +LE N + RL + +I+ + W+ S
Sbjct: 219 TNMDELH--SLIKNGQYSLK--DSVSKEGRKLIKGILEINPKKRLTLKEILETPWLQDCS 274
Query: 592 RLLE-WTPQETLAYKK 606
L+ +T E KK
Sbjct: 275 ETLDIFTDNEKETIKK 290
>UniRef50_A2ESP5 Cluster: CAMK family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: CAMK family protein kinase
- Trichomonas vaginalis G3
Length = 462
Score = 142 bits (343), Expect = 4e-32
Identities = 89/265 (33%), Positives = 138/265 (52%), Gaps = 18/265 (6%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y L + VG G ++ VY+ + + + A K+I K P++ RE+ ++ L
Sbjct: 15 YLLQEKVGHGGFSNVYMGIHLPTQ----TVCAIKVITKDKLPREIY----EREVKLMKML 66
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLH 138
+HP + + + + YY+ M ENG +L+ I K + E +AR QL L YLH
Sbjct: 67 DHPFCLTFYESLEDENNYYMAMENVENGTVLTEINKTFGLPEWKARHVFCQLICTLDYLH 126
Query: 139 -ELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILR 197
EL IAHRD+K EN++ N N++L DFG E + +T CGS +YA PE+L
Sbjct: 127 NELHIAHRDLKAENIMFDRNNNIRLIDFGLGNTFTEE----AMLKTACGSPAYAPPEMLC 182
Query: 198 GKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQQMGKKYRFRSRVASILSLECK 257
GKPY DLWS GVVLF M+ +PF D +++L ++ + + ++ SLE +
Sbjct: 183 GKPY-NDSADLWSAGVVLFAMVIGRLPFQDNSIQRLAQKIVYSQPQYSPNA----SLEVQ 237
Query: 258 TVVKHLLEPDPGLRHSATNVLDSEW 282
++ LLE DP R + + + W
Sbjct: 238 DLLSKLLEKDPAKRITIPEIYEHPW 262
Score = 118 bits (284), Expect = 5e-25
Identities = 72/237 (30%), Positives = 120/237 (50%), Gaps = 14/237 (5%)
Query: 351 SILACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERG 410
++ A KVI PR+ + RE++++ L HP + + + Y++ M +E G
Sbjct: 39 TVCAIKVITKDKLPREIYE----REVKLMKMLDHPFCLTFYESLEDENNYYMAMENVENG 94
Query: 411 DLLEFVLQRGAVQEDQARIWTRQLALAIQYMH-ELEIAHRDIKCENVLLTANQNVKLSDF 469
+L + + + E +AR QL + Y+H EL IAHRD+K EN++ N N++L DF
Sbjct: 95 TVLTEINKTFGLPEWKARHVFCQLICTLDYLHNELHIAHRDLKAENIMFDRNNNIRLIDF 154
Query: 470 GFARMCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMPF 529
G + E +T CGS +Y PE+L G PY D+WS G+V++ M+ +PF
Sbjct: 155 GLGNTFTE----EAMLKTACGSPAYAPPEMLCGKPY-NDSADLWSAGVVLFAMVIGRLPF 209
Query: 530 EDKHIKQLHQAQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
+D I++L Q + + +Y S + L+ +LE + R+ I +I W
Sbjct: 210 QDNSIQRLAQKIVYS----QPQYSPNASLEVQDLLSKLLEKDPAKRITIPEIYEHPW 262
>UniRef50_A0BZI1 Cluster: Chromosome undetermined scaffold_139,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_139,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 407
Score = 142 bits (343), Expect = 4e-32
Identities = 89/260 (34%), Positives = 138/260 (53%), Gaps = 16/260 (6%)
Query: 25 VGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRLNHPHLI 84
+G+G++ V L KE S LA K ++ A+ K V L REI + +LNHP++I
Sbjct: 76 LGQGSFGWVTLV----KEISTGKLLAMKAMKKAELFKYCTVDNLKREIKIQRKLNHPNII 131
Query: 85 HVHSIFQRKTKYYIFMRYTENGDLLSYILKNGCVSENQARVWTRQLALGLQYLHELEIAH 144
+ S F+ KT Y+ + Y E G L I K +SE++A + Q LG+ YLH+ +I H
Sbjct: 132 KLDSYFEDKTNVYLVLEYAEGGSLFKQIKKQRHLSEDEASHYLYQTCLGIDYLHKQKIIH 191
Query: 145 RDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEILRGKPYCPK 204
RDIK EN+LL N+K+ DFG+S E N L + +CG++ Y APE+++ + K
Sbjct: 192 RDIKPENLLLDNKGNIKICDFGWS---TEMGN---LKKAFCGTIEYMAPEMIKSQSTNYK 245
Query: 205 PTDLWSLGVVLFVMLNKSMPFDDTR-MRKLYEQQMGKKYRFRSRVASILSLECKTVVKHL 263
D+W LGV+L+ M+ PF K G ++ V S +CK+++ +
Sbjct: 246 -LDIWCLGVLLYEMVQGKPPFTGRNDQEKCQAILSGSPLKYDEYV----SEDCKSLISMI 300
Query: 264 LEPDPGLRHSATNVLDSEWI 283
L+ +P R S +L W+
Sbjct: 301 LQQNPFNRPSIQGILSHRWM 320
Score = 132 bits (320), Expect = 2e-29
Identities = 77/237 (32%), Positives = 135/237 (56%), Gaps = 17/237 (7%)
Query: 372 LPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDLLEFVLQRGAVQEDQARIWT 431
L REI++ KL+HP+++ S F+ + ++ + Y E G L + + ++ + ED+A +
Sbjct: 115 LKREIKIQRKLNHPNIIKLDSYFEDKTNVYLVLEYAEGGSLFKQIKKQRHLSEDEASHYL 174
Query: 432 RQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDFGFARMCVDKKLNEIRSETFCGS 491
Q L I Y+H+ +I HRDIK EN+LL N+K+ DFG++ + K + FCG+
Sbjct: 175 YQTCLGIDYLHKQKIIHRDIKPENLLLDNKGNIKICDFGWSTEMGNLK------KAFCGT 228
Query: 492 LSYTAPEIL--QGTPYLPKPTDVWSLGIVVYVMLNRAMPFEDKHIKQLHQAQINKNWKFR 549
+ Y APE++ Q T Y D+W LG+++Y M+ PF ++ ++ QA ++ +
Sbjct: 229 IEYMAPEMIKSQSTNY---KLDIWCLGVLLYEMVQGKPPFTGRNDQEKCQAILSGS---P 282
Query: 550 SRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEWIAMDSRLLEWTP-QETLAYK 605
+Y + +S++CK LI ++L+ N NR I I++ W M S++ + P E L Y+
Sbjct: 283 LKYDEYVSEDCKSLISMILQQNPFNRPSIQGILSHRW--MLSKIKQHPPLNENLTYR 337
>UniRef50_A0BX79 Cluster: Chromosome undetermined scaffold_134,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_134,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 596
Score = 142 bits (343), Expect = 4e-32
Identities = 85/282 (30%), Positives = 155/282 (54%), Gaps = 14/282 (4%)
Query: 19 YKLTKFVGEGAYAKVYLTEYSSKEDSHKSTLACKIIETAKAPKDFVVKFLPREIDVLVRL 78
Y L + +G+G++A+V+ K D + +A K+I + + + +EI++L +L
Sbjct: 13 YSLIREIGQGSFARVF----RGKLDGRQEDVAIKMISKQNVRNESM-SMIEKEIEILRQL 67
Query: 79 NHPHLIHVHSIFQRKTKYYIFMRYTENGDLLSYILK---NGCVSENQARVWTRQLALGLQ 135
+HP++I + + + YY+ Y ENGDL +YI K NG + E + R +QLA LQ
Sbjct: 68 DHPNIIKLIDFKRTQNHYYLVFEYCENGDLDAYIRKYSPNGKLPEEEVRRIVQQLAQALQ 127
Query: 136 YLHELEIAHRDIKCENVLLTANFNVKLSDFGFSRFCVESDNQPVLSETYCGSMSYAAPEI 195
+++L I HRD+K N+L++ NF +KL+DFGF+++ +E D +YCG+ APEI
Sbjct: 128 QMYKLRIVHRDLKLANILVSKNFQIKLADFGFAKY-MEEDQ---YLTSYCGTPLTMAPEI 183
Query: 196 LRGKPYCPKPTDLWSLGVVLFVMLNKSMPFDDTRMRKLYEQ-QMGKKYRFRSRVASILSL 254
L+ K Y K D+WS+GV+++ M+ PF + + + + K + S +SL
Sbjct: 184 LQRKQYNEK-CDVWSVGVIMYQMIYGRSPFVPPKGGNINDLIAIINKGDLQFPEISTISL 242
Query: 255 ECKTVVKHLLEPDPGLRHSATNVLDSEWIAMDSRLTTLNAVE 296
+ K ++ +L+ D R S + + W+ + + + +++
Sbjct: 243 KLKELLIQMLQQDFKKRISFRDFFEHSWLQGEVKADYIQSIK 284
Score = 121 bits (292), Expect = 5e-26
Identities = 79/241 (32%), Positives = 128/241 (53%), Gaps = 14/241 (5%)
Query: 353 LACKVIDTSTAPRDFVKKFLPREIEMLIKLSHPHLVHTHSIFQRRYKYFIFMRYMERGDL 412
+A K+I R+ + +EIE+L +L HP+++ + + Y++ Y E GDL
Sbjct: 39 VAIKMISKQNV-RNESMSMIEKEIEILRQLDHPNIIKLIDFKRTQNHYYLVFEYCENGDL 97
Query: 413 LEFVLQ---RGAVQEDQARIWTRQLALAIQYMHELEIAHRDIKCENVLLTANQNVKLSDF 469
++ + G + E++ R +QLA A+Q M++L I HRD+K N+L++ N +KL+DF
Sbjct: 98 DAYIRKYSPNGKLPEEEVRRIVQQLAQALQQMYKLRIVHRDLKLANILVSKNFQIKLADF 157
Query: 470 GFAR-MCVDKKLNEIRSETFCGSLSYTAPEILQGTPYLPKPTDVWSLGIVVYVMLNRAMP 528
GFA+ M D+ L ++CG+ APEILQ Y K DVWS+G+++Y M+ P
Sbjct: 158 GFAKYMEEDQYLT-----SYCGTPLTMAPEILQRKQYNEK-CDVWSVGVIMYQMIYGRSP 211
Query: 529 FEDKHIKQLHQ--AQINKNWKFRSRYIDTISDNCKRLIGLMLEPNHQNRLKIYDIVNSEW 586
F ++ A INK + I TIS K L+ ML+ + + R+ D W
Sbjct: 212 FVPPKGGNINDLIAIINKG-DLQFPEISTISLKLKELLIQMLQQDFKKRISFRDFFEHSW 270
Query: 587 I 587
+
Sbjct: 271 L 271
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.135 0.400
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 731,297,815
Number of Sequences: 1657284
Number of extensions: 30408797
Number of successful extensions: 122239
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 7585
Number of HSP's successfully gapped in prelim test: 3769
Number of HSP's that attempted gapping in prelim test: 74815
Number of HSP's gapped (non-prelim): 26994
length of query: 655
length of database: 575,637,011
effective HSP length: 106
effective length of query: 549
effective length of database: 399,964,907
effective search space: 219580733943
effective search space used: 219580733943
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 76 (34.7 bits)
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