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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001011-TA|BGIBMGA001011-PA|IPR001382|Glycoside
hydrolase, family 47
         (686 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CR457266-1|CAG33547.1|  578|Homo sapiens C20orf31 protein.            654   0.0  
BC016184-1|AAH16184.1|  578|Homo sapiens ER degradation enhancer...   654   0.0  
BC001371-1|AAH01371.1|  578|Homo sapiens ER degradation enhancer...   654   0.0  
AL356652-1|CAH73763.1|  578|Homo sapiens ER degradation enhancer...   654   0.0  
AL135844-1|CAI19292.1|  578|Homo sapiens ER degradation enhancer...   654   0.0  
AK023931-1|BAB14731.1|  578|Homo sapiens protein ( Homo sapiens ...   654   0.0  
AK001645-1|BAA91806.1|  578|Homo sapiens protein ( Homo sapiens ...   654   0.0  
AY358580-1|AAQ88943.1|  541|Homo sapiens C20orf31 protein.            592   e-168
D86967-1|BAA13203.2|  666|Homo sapiens KIAA0212 protein.              356   1e-97
BC019088-1|AAH19088.1|  657|Homo sapiens ER degradation enhancer...   356   1e-97
AL096819-3|CAI21741.1|  932|Homo sapiens ER degradation enhancer...   295   3e-79
AF288393-1|AAG60613.1|  889|Homo sapiens C1orf22 protein.             295   3e-79
BC006079-1|AAH06079.1|  699|Homo sapiens mannosidase, alpha, cla...   206   2e-52
BC002953-1|AAH02953.1|  699|Homo sapiens mannosidase, alpha, cla...   206   2e-52
AY358465-1|AAQ88830.1|  699|Homo sapiens MAN1B1 protein.              206   2e-52
AL929554-19|CAH72887.1|  699|Homo sapiens mannosidase, alpha, cl...   206   2e-52
AL807752-35|CAI12781.1|  699|Homo sapiens mannosidase, alpha, cl...   206   2e-52
AF148509-1|AAF03215.1|  699|Homo sapiens alpha 1,2-mannosidase p...   206   2e-52
AF145732-1|AAD45504.1|  663|Homo sapiens endoplasmic reticulum a...   206   2e-52
AL031280-2|CAI19714.1|  630|Homo sapiens mannosidase, alpha, cla...   198   5e-50
AL031280-1|CAI19713.1|  450|Homo sapiens mannosidase, alpha, cla...   198   5e-50
AF261655-1|AAF97058.1|  630|Homo sapiens 1,2-alpha-mannosidase I...   198   5e-50
BC063300-1|AAH63300.1|  641|Homo sapiens mannosidase, alpha, cla...   194   9e-49
AL358072-1|CAH71079.1|  641|Homo sapiens mannosidase, alpha, cla...   194   9e-49
AL157902-1|CAI22315.1|  641|Homo sapiens mannosidase, alpha, cla...   194   9e-49
AF027156-1|AAC26169.1|  641|Homo sapiens alpha 1,2-mannosidase I...   194   9e-49
AL078600-1|CAB75695.2|  653|Homo sapiens mannosidase, alpha, cla...   190   1e-47
AL022722-2|CAI20315.1|  653|Homo sapiens mannosidase, alpha, cla...   190   1e-47
X74837-1|CAA52831.1|  625|Homo sapiens Man9-mannosidase protein.      188   8e-47
AB209275-1|BAD92512.1|  482|Homo sapiens mannosidase, alpha, cla...   180   2e-44
BC105586-1|AAI05587.1|  242|Homo sapiens EDEM3 protein protein.       177   1e-43
AK023308-1|BAB14518.1|  618|Homo sapiens protein ( Homo sapiens ...   128   6e-29
AL358072-2|CAH71080.1|  343|Homo sapiens mannosidase, alpha, cla...   126   3e-28
AL157902-4|CAI22318.1|  343|Homo sapiens mannosidase, alpha, cla...   126   3e-28
AF053621-1|AAC26200.1|  358|Homo sapiens alpha 1,2-mannosidase I...   102   5e-21
AF053626-1|AAC26201.1|  251|Homo sapiens alpha 1,2-mannosidase I...    82   7e-15
AK074559-1|BAC11060.1|  178|Homo sapiens .2.1.113).  protein.          81   1e-14
AB209276-1|BAD92513.1|  185|Homo sapiens alpha 1,2-mannosidase v...    80   3e-14
BC065827-1|AAH65827.1|  367|Homo sapiens MAN1A1 protein protein.       79   5e-14
AL157902-2|CAI22316.1|  203|Homo sapiens mannosidase, alpha, cla...    72   8e-12
AL929554-1|CAH72871.2|  329|Homo sapiens mannosidase, alpha, cla...    58   8e-08
AL096819-2|CAI21740.1|  155|Homo sapiens ER degradation enhancer...    54   2e-06
AK023095-1|BAB14402.1|  155|Homo sapiens protein ( Homo sapiens ...    54   2e-06
AL157902-3|CAI22317.1|   97|Homo sapiens mannosidase, alpha, cla...    42   0.007
BC139779-1|AAI39780.1|  606|Homo sapiens zinc finger protein 652...    38   0.16 
AB023141-1|BAA76768.2|  617|Homo sapiens KIAA0924 protein protein.     38   0.16 
AK090938-1|BAC03551.1|  208|Homo sapiens protein ( Homo sapiens ...    35   0.83 
BC048959-1|AAH48959.1|  569|Homo sapiens ARID4B protein protein.       33   3.4  
BC041162-1|AAH41162.1|  722|Homo sapiens RNASEN protein protein.       33   3.4  
AL391994-7|CAI13752.1| 1071|Homo sapiens AT rich interactive dom...    33   3.4  
AL391994-6|CAI13751.1| 1226|Homo sapiens AT rich interactive dom...    33   3.4  
AL133418-7|CAI22963.1| 1071|Homo sapiens AT rich interactive dom...    33   3.4  
AL133418-6|CAI22962.1| 1226|Homo sapiens AT rich interactive dom...    33   3.4  
AK001121-1|BAA91511.1|  769|Homo sapiens protein ( Homo sapiens ...    33   3.4  
AF214114-1|AAF28341.2| 1226|Homo sapiens retinoblastoma-binding ...    33   3.4  
AF208045-1|AAF23433.3| 1213|Homo sapiens breast cancer-associate...    33   3.4  
AF189011-1|AAF80558.1| 1374|Homo sapiens ribonuclease III protein.     33   3.4  
AF116910-1|AAD29637.1|  541|Homo sapiens putative ribonuclease I...    33   3.4  
AL137350-1|CAB70705.1|  438|Homo sapiens hypothetical protein pr...    33   4.4  
BC112357-1|AAI12358.1|  488|Homo sapiens C9orf84 protein protein.      32   5.9  
BC041858-1|AAH41858.1|  356|Homo sapiens C9orf84 protein protein.      32   5.9  
BC016987-1|AAH16987.1|  284|Homo sapiens FAM44A protein protein.       32   5.9  
AL356491-3|CAM16657.1| 1405|Homo sapiens chromosome 9 open readi...    32   5.9  
AL356491-2|CAH72339.1|  488|Homo sapiens chromosome 9 open readi...    32   5.9  
AL356491-1|CAH72338.1| 1444|Homo sapiens chromosome 9 open readi...    32   5.9  
AL354877-2|CAH73770.1|  488|Homo sapiens chromosome 9 open readi...    32   5.9  
AL354877-1|CAH73769.1| 1444|Homo sapiens chromosome 9 open readi...    32   5.9  
AL135787-6|CAM13383.1| 1405|Homo sapiens chromosome 9 open readi...    32   5.9  
AL135787-1|CAI12399.1| 1444|Homo sapiens chromosome 9 open readi...    32   5.9  
AK057341-1|BAB71436.1|  488|Homo sapiens protein ( Homo sapiens ...    32   5.9  
AB037748-1|BAA92565.2| 1804|Homo sapiens KIAA1327 protein protein.     32   5.9  

>CR457266-1|CAG33547.1|  578|Homo sapiens C20orf31 protein.
          Length = 578

 Score =  654 bits (1615), Expect = 0.0
 Identities = 291/452 (64%), Positives = 358/452 (79%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           MF HAYDSYL  A+P+DELRPL+CDG DTWGS+SLTLIDALDTL I+GN SEF RVV+++
Sbjct: 42  MFYHAYDSYLENAFPFDELRPLTCDGHDTWGSFSLTLIDALDTLLILGNVSEFQRVVEVL 101

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
                FD D+N SVFETNIR+VGGLLSAHLLS K G+++E GWPC+GPLLR+AE+ A++L
Sbjct: 102 QDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKL 161

Query: 121 IAAFDTTTGMPYGTINLRSGVPPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAYNA 180
           + AF T TGMPYGT+NL  GV PGET +TCTAG+GTFI+EF TLS LTGDP++E+VA  A
Sbjct: 162 LPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVA 221

Query: 181 LKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKPELMSMFL 240
           L  L+  RS IGL+GNHIDV+TG+W AQDAGIG G+DSY+EYLVKGAILL+  +LM+MFL
Sbjct: 222 LMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFL 281

Query: 241 EARQSIEKYLKKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGESDAAMRIIHNYHS 300
           E  ++I  Y + DDW++W  M +G V++PVFQSLE+YWPGL SLIG+ D AMR   NY++
Sbjct: 282 EYNKAIRNYTRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYT 341

Query: 301 VWRQYGFTPEVYNLGTGEASSSRESYPLRPELIESIMYLYRDTRDPILLQMGEDILRSIQ 360
           VW+Q+G  PE YN+  G     RE YPLRPELIES MYLYR T DP LL++G D + SI+
Sbjct: 342 VWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE 401

Query: 361 HSARTPCGYATIKDVRDHRKEDRMESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPN 420
             ++  CG+ATIKD+RDH+ ++RMESFFLAET KYLYLLFDP NFIHN G     + TP 
Sbjct: 402 KISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPY 461

Query: 421 GECVVDLGGYIFNTEAHPIDPNMLYCCHEARQ 452
           GEC++  GGYIFNTEAHPIDP  L+CC   ++
Sbjct: 462 GECILGAGGYIFNTEAHPIDPAALHCCQRLKE 493


>BC016184-1|AAH16184.1|  578|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 2 protein.
          Length = 578

 Score =  654 bits (1615), Expect = 0.0
 Identities = 291/452 (64%), Positives = 358/452 (79%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           MF HAYDSYL  A+P+DELRPL+CDG DTWGS+SLTLIDALDTL I+GN SEF RVV+++
Sbjct: 42  MFYHAYDSYLENAFPFDELRPLTCDGHDTWGSFSLTLIDALDTLLILGNVSEFQRVVEVL 101

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
                FD D+N SVFETNIR+VGGLLSAHLLS K G+++E GWPC+GPLLR+AE+ A++L
Sbjct: 102 QDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKL 161

Query: 121 IAAFDTTTGMPYGTINLRSGVPPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAYNA 180
           + AF T TGMPYGT+NL  GV PGET +TCTAG+GTFI+EF TLS LTGDP++E+VA  A
Sbjct: 162 LPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVA 221

Query: 181 LKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKPELMSMFL 240
           L  L+  RS IGL+GNHIDV+TG+W AQDAGIG G+DSY+EYLVKGAILL+  +LM+MFL
Sbjct: 222 LMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFL 281

Query: 241 EARQSIEKYLKKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGESDAAMRIIHNYHS 300
           E  ++I  Y + DDW++W  M +G V++PVFQSLE+YWPGL SLIG+ D AMR   NY++
Sbjct: 282 EYNKAIRNYTRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYT 341

Query: 301 VWRQYGFTPEVYNLGTGEASSSRESYPLRPELIESIMYLYRDTRDPILLQMGEDILRSIQ 360
           VW+Q+G  PE YN+  G     RE YPLRPELIES MYLYR T DP LL++G D + SI+
Sbjct: 342 VWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE 401

Query: 361 HSARTPCGYATIKDVRDHRKEDRMESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPN 420
             ++  CG+ATIKD+RDH+ ++RMESFFLAET KYLYLLFDP NFIHN G     + TP 
Sbjct: 402 KISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDTVITPY 461

Query: 421 GECVVDLGGYIFNTEAHPIDPNMLYCCHEARQ 452
           GEC++  GGYIFNTEAHPIDP  L+CC   ++
Sbjct: 462 GECILGAGGYIFNTEAHPIDPAALHCCQRLKE 493


>BC001371-1|AAH01371.1|  578|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 2 protein.
          Length = 578

 Score =  654 bits (1615), Expect = 0.0
 Identities = 291/452 (64%), Positives = 358/452 (79%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           MF HAYDSYL  A+P+DELRPL+CDG DTWGS+SLTLIDALDTL I+GN SEF RVV+++
Sbjct: 42  MFYHAYDSYLENAFPFDELRPLTCDGHDTWGSFSLTLIDALDTLLILGNVSEFQRVVEVL 101

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
                FD D+N SVFETNIR+VGGLLSAHLLS K G+++E GWPC+GPLLR+AE+ A++L
Sbjct: 102 QDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKL 161

Query: 121 IAAFDTTTGMPYGTINLRSGVPPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAYNA 180
           + AF T TGMPYGT+NL  GV PGET +TCTAG+GTFI+EF TLS LTGDP++E+VA  A
Sbjct: 162 LPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVA 221

Query: 181 LKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKPELMSMFL 240
           L  L+  RS IGL+GNHIDV+TG+W AQDAGIG G+DSY+EYLVKGAILL+  +LM+MFL
Sbjct: 222 LMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFL 281

Query: 241 EARQSIEKYLKKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGESDAAMRIIHNYHS 300
           E  ++I  Y + DDW++W  M +G V++PVFQSLE+YWPGL SLIG+ D AMR   NY++
Sbjct: 282 EYNKAIRNYTRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYT 341

Query: 301 VWRQYGFTPEVYNLGTGEASSSRESYPLRPELIESIMYLYRDTRDPILLQMGEDILRSIQ 360
           VW+Q+G  PE YN+  G     RE YPLRPELIES MYLYR T DP LL++G D + SI+
Sbjct: 342 VWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE 401

Query: 361 HSARTPCGYATIKDVRDHRKEDRMESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPN 420
             ++  CG+ATIKD+RDH+ ++RMESFFLAET KYLYLLFDP NFIHN G     + TP 
Sbjct: 402 KISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDTVITPY 461

Query: 421 GECVVDLGGYIFNTEAHPIDPNMLYCCHEARQ 452
           GEC++  GGYIFNTEAHPIDP  L+CC   ++
Sbjct: 462 GECILGAGGYIFNTEAHPIDPAALHCCQRLKE 493


>AL356652-1|CAH73763.1|  578|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 2 protein.
          Length = 578

 Score =  654 bits (1615), Expect = 0.0
 Identities = 291/452 (64%), Positives = 358/452 (79%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           MF HAYDSYL  A+P+DELRPL+CDG DTWGS+SLTLIDALDTL I+GN SEF RVV+++
Sbjct: 42  MFYHAYDSYLENAFPFDELRPLTCDGHDTWGSFSLTLIDALDTLLILGNVSEFQRVVEVL 101

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
                FD D+N SVFETNIR+VGGLLSAHLLS K G+++E GWPC+GPLLR+AE+ A++L
Sbjct: 102 QDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKL 161

Query: 121 IAAFDTTTGMPYGTINLRSGVPPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAYNA 180
           + AF T TGMPYGT+NL  GV PGET +TCTAG+GTFI+EF TLS LTGDP++E+VA  A
Sbjct: 162 LPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVA 221

Query: 181 LKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKPELMSMFL 240
           L  L+  RS IGL+GNHIDV+TG+W AQDAGIG G+DSY+EYLVKGAILL+  +LM+MFL
Sbjct: 222 LMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFL 281

Query: 241 EARQSIEKYLKKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGESDAAMRIIHNYHS 300
           E  ++I  Y + DDW++W  M +G V++PVFQSLE+YWPGL SLIG+ D AMR   NY++
Sbjct: 282 EYNKAIRNYTRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYT 341

Query: 301 VWRQYGFTPEVYNLGTGEASSSRESYPLRPELIESIMYLYRDTRDPILLQMGEDILRSIQ 360
           VW+Q+G  PE YN+  G     RE YPLRPELIES MYLYR T DP LL++G D + SI+
Sbjct: 342 VWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE 401

Query: 361 HSARTPCGYATIKDVRDHRKEDRMESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPN 420
             ++  CG+ATIKD+RDH+ ++RMESFFLAET KYLYLLFDP NFIHN G     + TP 
Sbjct: 402 KISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPY 461

Query: 421 GECVVDLGGYIFNTEAHPIDPNMLYCCHEARQ 452
           GEC++  GGYIFNTEAHPIDP  L+CC   ++
Sbjct: 462 GECILGAGGYIFNTEAHPIDPAALHCCQRLKE 493


>AL135844-1|CAI19292.1|  578|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 2 protein.
          Length = 578

 Score =  654 bits (1615), Expect = 0.0
 Identities = 291/452 (64%), Positives = 358/452 (79%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           MF HAYDSYL  A+P+DELRPL+CDG DTWGS+SLTLIDALDTL I+GN SEF RVV+++
Sbjct: 42  MFYHAYDSYLENAFPFDELRPLTCDGHDTWGSFSLTLIDALDTLLILGNVSEFQRVVEVL 101

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
                FD D+N SVFETNIR+VGGLLSAHLLS K G+++E GWPC+GPLLR+AE+ A++L
Sbjct: 102 QDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKL 161

Query: 121 IAAFDTTTGMPYGTINLRSGVPPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAYNA 180
           + AF T TGMPYGT+NL  GV PGET +TCTAG+GTFI+EF TLS LTGDP++E+VA  A
Sbjct: 162 LPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVA 221

Query: 181 LKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKPELMSMFL 240
           L  L+  RS IGL+GNHIDV+TG+W AQDAGIG G+DSY+EYLVKGAILL+  +LM+MFL
Sbjct: 222 LMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFL 281

Query: 241 EARQSIEKYLKKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGESDAAMRIIHNYHS 300
           E  ++I  Y + DDW++W  M +G V++PVFQSLE+YWPGL SLIG+ D AMR   NY++
Sbjct: 282 EYNKAIRNYTRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYT 341

Query: 301 VWRQYGFTPEVYNLGTGEASSSRESYPLRPELIESIMYLYRDTRDPILLQMGEDILRSIQ 360
           VW+Q+G  PE YN+  G     RE YPLRPELIES MYLYR T DP LL++G D + SI+
Sbjct: 342 VWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE 401

Query: 361 HSARTPCGYATIKDVRDHRKEDRMESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPN 420
             ++  CG+ATIKD+RDH+ ++RMESFFLAET KYLYLLFDP NFIHN G     + TP 
Sbjct: 402 KISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPY 461

Query: 421 GECVVDLGGYIFNTEAHPIDPNMLYCCHEARQ 452
           GEC++  GGYIFNTEAHPIDP  L+CC   ++
Sbjct: 462 GECILGAGGYIFNTEAHPIDPAALHCCQRLKE 493


>AK023931-1|BAB14731.1|  578|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13869 fis, clone THYRO1001287, weakly similar to
           MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE (EC
           3.2.1.113). ).
          Length = 578

 Score =  654 bits (1615), Expect = 0.0
 Identities = 291/452 (64%), Positives = 358/452 (79%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           MF HAYDSYL  A+P+DELRPL+CDG DTWGS+SLTLIDALDTL I+GN SEF RVV+++
Sbjct: 42  MFYHAYDSYLENAFPFDELRPLTCDGHDTWGSFSLTLIDALDTLLILGNVSEFQRVVEVL 101

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
                FD D+N SVFETNIR+VGGLLSAHLLS K G+++E GWPC+GPLLR+AE+ A++L
Sbjct: 102 QDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKL 161

Query: 121 IAAFDTTTGMPYGTINLRSGVPPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAYNA 180
           + AF T TGMPYGT+NL  GV PGET +TCTAG+GTFI+EF TLS LTGDP++E+VA  A
Sbjct: 162 LPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVA 221

Query: 181 LKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKPELMSMFL 240
           L  L+  RS IGL+GNHIDV+TG+W AQDAGIG G+DSY+EYLVKGAILL+  +LM+MFL
Sbjct: 222 LMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFL 281

Query: 241 EARQSIEKYLKKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGESDAAMRIIHNYHS 300
           E  ++I  Y + DDW++W  M +G V++PVFQSLE+YWPGL SLIG+ D AMR   NY++
Sbjct: 282 EYNKAIRNYTRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYT 341

Query: 301 VWRQYGFTPEVYNLGTGEASSSRESYPLRPELIESIMYLYRDTRDPILLQMGEDILRSIQ 360
           VW+Q+G  PE YN+  G     RE YPLRPELIES MYLYR T DP LL++G D + SI+
Sbjct: 342 VWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE 401

Query: 361 HSARTPCGYATIKDVRDHRKEDRMESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPN 420
             ++  CG+ATIKD+RDH+ ++RMESFFLAET KYLYLLFDP NFIHN G     + TP 
Sbjct: 402 KISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPY 461

Query: 421 GECVVDLGGYIFNTEAHPIDPNMLYCCHEARQ 452
           GEC++  GGYIFNTEAHPIDP  L+CC   ++
Sbjct: 462 GECILGAGGYIFNTEAHPIDPAALHCCQRLKE 493


>AK001645-1|BAA91806.1|  578|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10783 fis, clone NT2RP4000417, weakly similar to
           MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE (EC
           3.2.1.113). ).
          Length = 578

 Score =  654 bits (1615), Expect = 0.0
 Identities = 291/452 (64%), Positives = 358/452 (79%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           MF HAYDSYL  A+P+DELRPL+CDG DTWGS+SLTLIDALDTL I+GN SEF RVV+++
Sbjct: 42  MFYHAYDSYLENAFPFDELRPLTCDGHDTWGSFSLTLIDALDTLLILGNVSEFQRVVEVL 101

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
                FD D+N SVFETNIR+VGGLLSAHLLS K G+++E GWPC+GPLLR+AE+ A++L
Sbjct: 102 QDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKL 161

Query: 121 IAAFDTTTGMPYGTINLRSGVPPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAYNA 180
           + AF T TGMPYGT+NL  GV PGET +TCTAG+GTFI+EF TLS LTGDP++E+VA  A
Sbjct: 162 LPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVA 221

Query: 181 LKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKPELMSMFL 240
           L  L+  RS IGL+GNHIDV+TG+W AQDAGIG G+DSY+EYLVKGAILL+  +LM+MFL
Sbjct: 222 LMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFL 281

Query: 241 EARQSIEKYLKKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGESDAAMRIIHNYHS 300
           E  ++I  Y + DDW++W  M +G V++PVFQSLE+YWPGL SLIG+ D AMR   NY++
Sbjct: 282 EYNKAIRNYTRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYT 341

Query: 301 VWRQYGFTPEVYNLGTGEASSSRESYPLRPELIESIMYLYRDTRDPILLQMGEDILRSIQ 360
           VW+Q+G  PE YN+  G     RE YPLRPELIES MYLYR T DP LL++G D + SI+
Sbjct: 342 VWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE 401

Query: 361 HSARTPCGYATIKDVRDHRKEDRMESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPN 420
             ++  CG+ATIKD+RDH+ ++RMESFFLAET KYLYLLFDP NFIHN G     + TP 
Sbjct: 402 KISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDTVITPY 461

Query: 421 GECVVDLGGYIFNTEAHPIDPNMLYCCHEARQ 452
           GEC++  GGYIFNTEAHPIDP  L+CC   ++
Sbjct: 462 GECILGAGGYIFNTEAHPIDPAALHCCQRLKE 493


>AY358580-1|AAQ88943.1|  541|Homo sapiens C20orf31 protein.
          Length = 541

 Score =  592 bits (1462), Expect = e-168
 Identities = 266/421 (63%), Positives = 330/421 (78%)

Query: 32  SYSLTLIDALDTLAIMGNYSEFNRVVDIVLQKRHFDADINVSVFETNIRIVGGLLSAHLL 91
           S+SLTLIDALDTL I+GN SEF RVV+++     FD D+N SVFETNIR+VGGLLSAHLL
Sbjct: 36  SFSLTLIDALDTLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLL 95

Query: 92  SHKTGMKLEPGWPCNGPLLRLAEDVAQRLIAAFDTTTGMPYGTINLRSGVPPGETSITCT 151
           S K G+++E GWPC+GPLLR+AE+ A++L+ AF T TGMPYGT+NL  GV PGET +TCT
Sbjct: 96  SKKAGVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNPGETPVTCT 155

Query: 152 AGVGTFIIEFGTLSRLTGDPLYEEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAG 211
           AG+GTFI+EF TLS LTGDP++E+VA  AL  L+  RS IGL+GNHIDV+TG+W AQDAG
Sbjct: 156 AGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWESRSDIGLVGNHIDVLTGKWVAQDAG 215

Query: 212 IGGGIDSYYEYLVKGAILLEKPELMSMFLEARQSIEKYLKKDDWFVWATMLRGHVTLPVF 271
           IG G+DSY+EYLVKGAILL+  +LM+MFLE  ++I  Y + DDW++W  M +G V++PVF
Sbjct: 216 IGAGVDSYFEYLVKGAILLQDKKLMAMFLEYNKAIRNYTRFDDWYLWVQMYKGTVSMPVF 275

Query: 272 QSLESYWPGLLSLIGESDAAMRIIHNYHSVWRQYGFTPEVYNLGTGEASSSRESYPLRPE 331
           QSLE+YWPGL SLIG+ D AMR   NY++VW+Q+G  PE YN+  G     RE YPLRPE
Sbjct: 276 QSLEAYWPGLQSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPE 335

Query: 332 LIESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDHRKEDRMESFFLAE 391
           LIES MYLYR T DP LL++G D + SI+  ++  CG+ATIKD+RDH+ ++RMESFFLAE
Sbjct: 336 LIESAMYLYRATGDPTLLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAE 395

Query: 392 TTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPIDPNMLYCCHEAR 451
           T KYLYLLFDP NFIHN G     + TP GEC++  GGYIFNTEAHPID   L+CC   +
Sbjct: 396 TVKYLYLLFDPTNFIHNNGSTFDAVITPYGECILGAGGYIFNTEAHPIDLAALHCCQRLK 455

Query: 452 Q 452
           +
Sbjct: 456 E 456


>D86967-1|BAA13203.2|  666|Homo sapiens KIAA0212 protein.
          Length = 666

 Score =  356 bits (876), Expect = 1e-97
 Identities = 195/440 (44%), Positives = 267/440 (60%), Gaps = 30/440 (6%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGV-------------DTWGSYSLTLIDALDTLAIM 47
           MF   YD+Y+ +A+P DEL P+ C G              D  G+YSLTL+DALDTLAIM
Sbjct: 146 MFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIM 205

Query: 48  GNYSEFNRVVDIVLQKRHFDADINVSVFETNIRIVGGLLSAH--LLSHKTGMKLEPGWPC 105
           GN SEF + V +V+    FD D  V VFE  IR++G LLSAH  +   K           
Sbjct: 206 GNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDY 265

Query: 106 NGPLLRLAEDVAQRLIAAFDTT-TGMPYGTINLRSGVPPGETSITCTAGVGTFIIEFGTL 164
           +  LL +A D+A RL+ AF+ T TG+PY  +NL++GVPP   + TCTAG G+ ++EFG L
Sbjct: 266 DNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNETCTAGAGSLLVEFGIL 325

Query: 165 SRLTGDPLYEEVAYNALKALYHHRS-PIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYL 223
           SRL GD  +E VA  A+KAL++ RS   GLLGN +++ TG W  + +G+G G+DS+YEYL
Sbjct: 326 SRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEYL 385

Query: 224 VKGAILLEKPELMSMFLEARQSIEKYLKKD-----------DWFVWATMLRGHVTLPVFQ 272
           +K  IL  + E + MF  A QSI+ YL++              +V   M  G +      
Sbjct: 386 LKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNVNMFSGQLMNTWID 445

Query: 273 SLESYWPGLLSLIGESDAAMRIIHNYHSVWRQYGFTPEVYNLGTGEASSSRESYPLRPEL 332
           SL++++PGL  LIG+ + A+ +   Y+++W++YG  PE YN      +     YPLRPEL
Sbjct: 446 SLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQL--QAPDVLFYPLRPEL 503

Query: 333 IESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDHRKEDRMESFFLAET 392
           +ES   LY+ T++P  L +G DIL+S++   +  CGYAT+  V D   EDRMESFFL+ET
Sbjct: 504 VESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKSTEDRMESFFLSET 563

Query: 393 TKYLYLLFDPDNFIHNPGVR 412
            KYLYLLFD DN +H  G R
Sbjct: 564 CKYLYLLFDEDNPVHKSGTR 583


>BC019088-1|AAH19088.1|  657|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 1 protein.
          Length = 657

 Score =  356 bits (876), Expect = 1e-97
 Identities = 195/440 (44%), Positives = 267/440 (60%), Gaps = 30/440 (6%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGV-------------DTWGSYSLTLIDALDTLAIM 47
           MF   YD+Y+ +A+P DEL P+ C G              D  G+YSLTL+DALDTLAIM
Sbjct: 137 MFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIM 196

Query: 48  GNYSEFNRVVDIVLQKRHFDADINVSVFETNIRIVGGLLSAH--LLSHKTGMKLEPGWPC 105
           GN SEF + V +V+    FD D  V VFE  IR++G LLSAH  +   K           
Sbjct: 197 GNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDY 256

Query: 106 NGPLLRLAEDVAQRLIAAFDTT-TGMPYGTINLRSGVPPGETSITCTAGVGTFIIEFGTL 164
           +  LL +A D+A RL+ AF+ T TG+PY  +NL++GVPP   + TCTAG G+ ++EFG L
Sbjct: 257 DNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNETCTAGAGSLLVEFGIL 316

Query: 165 SRLTGDPLYEEVAYNALKALYHHRS-PIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYL 223
           SRL GD  +E VA  A+KAL++ RS   GLLGN +++ TG W  + +G+G G+DS+YEYL
Sbjct: 317 SRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEYL 376

Query: 224 VKGAILLEKPELMSMFLEARQSIEKYLKKD-----------DWFVWATMLRGHVTLPVFQ 272
           +K  IL  + E + MF  A QSI+ YL++              +V   M  G +      
Sbjct: 377 LKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNVNMFSGQLMNTWID 436

Query: 273 SLESYWPGLLSLIGESDAAMRIIHNYHSVWRQYGFTPEVYNLGTGEASSSRESYPLRPEL 332
           SL++++PGL  LIG+ + A+ +   Y+++W++YG  PE YN      +     YPLRPEL
Sbjct: 437 SLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQL--QAPDVLFYPLRPEL 494

Query: 333 IESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDHRKEDRMESFFLAET 392
           +ES   LY+ T++P  L +G DIL+S++   +  CGYAT+  V D   EDRMESFFL+ET
Sbjct: 495 VESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKSTEDRMESFFLSET 554

Query: 393 TKYLYLLFDPDNFIHNPGVR 412
            KYLYLLFD DN +H  G R
Sbjct: 555 CKYLYLLFDEDNPVHKSGTR 574


>AL096819-3|CAI21741.1|  932|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 3 protein.
          Length = 932

 Score =  295 bits (725), Expect = 3e-79
 Identities = 173/429 (40%), Positives = 244/429 (56%), Gaps = 29/429 (6%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGV------------DTWGSYSLTLIDALDTLAIMG 48
           MF HAY +Y+ +AYP DEL PL+C G             D  G +SLTLID+LDTL ++ 
Sbjct: 59  MFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVLN 118

Query: 49  NYSEFNRVVDIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGP 108
              EF   V  VL+  + D D+ VSVFETNIR++GGLL  H L+     K E     N  
Sbjct: 119 KTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEYMQWYNDE 178

Query: 109 LLRLAEDVAQRLIAAFDTTTGMPYGTINLRSGV--PPGETSI---TCTAGVGTFIIEFGT 163
           LL++A+ +  +L+ AF+TT+G+PY  INL+ G+  P   T     TCTA  GT I+EF  
Sbjct: 179 LLQMAKQLGYKLLPAFNTTSGLPYPRINLKFGIRKPEARTGTETDTCTACAGTLILEFAA 238

Query: 164 LSRLTGDPLYEEVAYNALKALYHHRS-PIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEY 222
           LSR TG  ++EE A  AL  L+  R     L+G  I++ TG W  +D+G+G GIDSYYEY
Sbjct: 239 LSRFTGATIFEEYARKALDFLWEKRQRSSNLVGVTINIHTGDWVRKDSGVGAGIDSYYEY 298

Query: 223 LVKGAILLEKPELMSMFLEARQSIEKYLKKD----DWFVWATMLRGHVTLPVFQSLESYW 278
           L+K  +LL     +  F     +I +Y+ +     D  +   ML     +    +L +++
Sbjct: 299 LLKAYVLLGDDSFLERFNTHYDAIMRYISQPPLLLDVHIHKPMLNARTWM---DALLAFF 355

Query: 279 PGLLSLIGESDAAMRIIHNYHSVWRQYGFTPEVYNLGTGEASSSRESYPLRPELIESIMY 338
           PGL  L G+   A+      + V +++ F PE +   T +       +PLRPE  ES  +
Sbjct: 356 PGLQVLKGDIRPAIETHEMLYQVIKKHNFLPEAF---TTDFRVHWAQHPLRPEFAESTYF 412

Query: 339 LYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDHRKEDRMESFFLAETTKYLYL 398
           LY+ T DP  L++G+ ++ ++   AR PCG+A +KDVR    EDRM+SFFLAE  KYLYL
Sbjct: 413 LYKATGDPYYLEVGKTLIENLNKYARVPCGFAAMKDVRTGSHEDRMDSFFLAEMFKYLYL 472

Query: 399 LF-DPDNFI 406
           LF D ++ I
Sbjct: 473 LFADKEDII 481


>AF288393-1|AAG60613.1|  889|Homo sapiens C1orf22 protein.
          Length = 889

 Score =  295 bits (725), Expect = 3e-79
 Identities = 173/429 (40%), Positives = 244/429 (56%), Gaps = 29/429 (6%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGV------------DTWGSYSLTLIDALDTLAIMG 48
           MF HAY +Y+ +AYP DEL PL+C G             D  G +SLTLID+LDTL ++ 
Sbjct: 16  MFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVLN 75

Query: 49  NYSEFNRVVDIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGP 108
              EF   V  VL+  + D D+ VSVFETNIR++GGLL  H L+     K E     N  
Sbjct: 76  KTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEYMQWYNDE 135

Query: 109 LLRLAEDVAQRLIAAFDTTTGMPYGTINLRSGV--PPGETSI---TCTAGVGTFIIEFGT 163
           LL++A+ +  +L+ AF+TT+G+PY  INL+ G+  P   T     TCTA  GT I+EF  
Sbjct: 136 LLQMAKQLGYKLLPAFNTTSGLPYPRINLKFGIRKPEARTGTETDTCTACAGTLILEFAA 195

Query: 164 LSRLTGDPLYEEVAYNALKALYHHRS-PIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEY 222
           LSR TG  ++EE A  AL  L+  R     L+G  I++ TG W  +D+G+G GIDSYYEY
Sbjct: 196 LSRFTGATIFEEYARKALDFLWEKRQRSSNLVGVTINIHTGDWVRKDSGVGAGIDSYYEY 255

Query: 223 LVKGAILLEKPELMSMFLEARQSIEKYLKKD----DWFVWATMLRGHVTLPVFQSLESYW 278
           L+K  +LL     +  F     +I +Y+ +     D  +   ML     +    +L +++
Sbjct: 256 LLKAYVLLGDDSFLERFNTHYDAIMRYISQPPLLLDVHIHKPMLNARTWM---DALLAFF 312

Query: 279 PGLLSLIGESDAAMRIIHNYHSVWRQYGFTPEVYNLGTGEASSSRESYPLRPELIESIMY 338
           PGL  L G+   A+      + V +++ F PE +   T +       +PLRPE  ES  +
Sbjct: 313 PGLQVLKGDIRPAIETHEMLYQVIKKHNFLPEAF---TTDFRVHWAQHPLRPEFAESTYF 369

Query: 339 LYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDHRKEDRMESFFLAETTKYLYL 398
           LY+ T DP  L++G+ ++ ++   AR PCG+A +KDVR    EDRM+SFFLAE  KYLYL
Sbjct: 370 LYKATGDPYYLEVGKTLIENLNKYARVPCGFAAMKDVRTGSHEDRMDSFFLAEMFKYLYL 429

Query: 399 LF-DPDNFI 406
           LF D ++ I
Sbjct: 430 LFADKEDII 438


>BC006079-1|AAH06079.1|  699|Homo sapiens mannosidase, alpha, class
           1B, member 1 protein.
          Length = 699

 Score =  206 bits (503), Expect = 2e-52
 Identities = 165/471 (35%), Positives = 240/471 (50%), Gaps = 65/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           +F HA+  Y ++A+ +DEL+P+S      W    LTLIDALDT+ I+G   EF      V
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVS-RSFSEWFGLGLTLIDALDTMWILGLRKEFEEARKWV 314

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
            +K HF+ D++V++FE+ IRI+GGLLSA+   H +G  L          LR AED   RL
Sbjct: 315 SKKLHFEKDVDVNLFESTIRILGGLLSAY---HLSGDSL---------FLRKAEDFGNRL 362

Query: 121 IAAFDTTTGMPYGTINLRSGV--PPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAY 178
           + AF T + +PY  +N+ +GV  PP  TS +  A V +  +EF  LSRLTGD  ++E   
Sbjct: 363 MPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVE 422

Query: 179 NALKALYH-HRSPIGLLGNHIDVMTGRWTAQDA-GIGGGIDSYYEYLVKGAILLEKPE-- 234
              + ++       GL+   I+  +G +T      +G   DSYYEYL+K  I   K E  
Sbjct: 423 KVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQ 482

Query: 235 LMSMFLEARQSIEKYLKKDD-----WFVWATMLRGHVTLPVFQSLESYWPGLLSL----- 284
           L+  ++EA + +  +L +        FV   +  G  +  +   L  + PG L+L     
Sbjct: 483 LLEDYVEAIEGVRTHLLRHSEPSKLTFV-GELAHGRFSAKM-DHLVCFLPGTLALGVYHG 540

Query: 285 --IGESDAAMRIIHNYHSVWRQY--GFTPEV--YNLGTGEASSSRESYP------LRPEL 332
                 + A  ++   + + RQ   G +PE+  +NL         E  P      LRPE 
Sbjct: 541 LPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPET 600

Query: 333 IESIMYLYRDTRDPILLQMGEDILRSIQHSARTPC-GYATIKDVRDHRK---EDRMESFF 388
           +ES+ YLYR T D      G +IL+S     R P  GY++I +V+D +K    D+MESFF
Sbjct: 601 VESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFF 660

Query: 389 LAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           L ET KYL+LLF                D PN   ++ L  Y+FNTEAHP+
Sbjct: 661 LGETLKYLFLLFS---------------DDPN---LLSLDAYVFNTEAHPL 693


>BC002953-1|AAH02953.1|  699|Homo sapiens mannosidase, alpha, class
           1B, member 1 protein.
          Length = 699

 Score =  206 bits (503), Expect = 2e-52
 Identities = 165/471 (35%), Positives = 240/471 (50%), Gaps = 65/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           +F HA+  Y ++A+ +DEL+P+S      W    LTLIDALDT+ I+G   EF      V
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVS-RSFSEWFGLGLTLIDALDTMWILGLRKEFEEARKWV 314

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
            +K HF+ D++V++FE+ IRI+GGLLSA+   H +G  L          LR AED   RL
Sbjct: 315 SKKLHFEKDVDVNLFESTIRILGGLLSAY---HLSGDSL---------FLRKAEDFGNRL 362

Query: 121 IAAFDTTTGMPYGTINLRSGV--PPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAY 178
           + AF T + +PY  +N+ +GV  PP  TS +  A V +  +EF  LSRLTGD  ++E   
Sbjct: 363 MPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVE 422

Query: 179 NALKALYH-HRSPIGLLGNHIDVMTGRWTAQDA-GIGGGIDSYYEYLVKGAILLEKPE-- 234
              + ++       GL+   I+  +G +T      +G   DSYYEYL+K  I   K E  
Sbjct: 423 KVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQ 482

Query: 235 LMSMFLEARQSIEKYLKKDD-----WFVWATMLRGHVTLPVFQSLESYWPGLLSL----- 284
           L+  ++EA + +  +L +        FV   +  G  +  +   L  + PG L+L     
Sbjct: 483 LLEDYVEAIEGVRTHLLRHSEPSKLTFV-GELAHGRFSAKM-DHLVCFLPGTLALGVYHG 540

Query: 285 --IGESDAAMRIIHNYHSVWRQY--GFTPEV--YNLGTGEASSSRESYP------LRPEL 332
                 + A  ++   + + RQ   G +PE+  +NL         E  P      LRPE 
Sbjct: 541 LPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPET 600

Query: 333 IESIMYLYRDTRDPILLQMGEDILRSIQHSARTPC-GYATIKDVRDHRK---EDRMESFF 388
           +ES+ YLYR T D      G +IL+S     R P  GY++I +V+D +K    D+MESFF
Sbjct: 601 VESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFF 660

Query: 389 LAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           L ET KYL+LLF                D PN   ++ L  Y+FNTEAHP+
Sbjct: 661 LGETLKYLFLLFS---------------DDPN---LLSLDAYVFNTEAHPL 693


>AY358465-1|AAQ88830.1|  699|Homo sapiens MAN1B1 protein.
          Length = 699

 Score =  206 bits (503), Expect = 2e-52
 Identities = 165/471 (35%), Positives = 240/471 (50%), Gaps = 65/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           +F HA+  Y ++A+ +DEL+P+S      W    LTLIDALDT+ I+G   EF      V
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVS-RSFSEWFGLGLTLIDALDTMWILGLRKEFEEARKWV 314

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
            +K HF+ D++V++FE+ IRI+GGLLSA+   H +G  L          LR AED   RL
Sbjct: 315 SKKLHFEKDVDVNLFESTIRILGGLLSAY---HLSGDSL---------FLRKAEDFGNRL 362

Query: 121 IAAFDTTTGMPYGTINLRSGV--PPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAY 178
           + AF T + +PY  +N+ +GV  PP  TS +  A V +  +EF  LSRLTGD  ++E   
Sbjct: 363 MPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVE 422

Query: 179 NALKALYH-HRSPIGLLGNHIDVMTGRWTAQDA-GIGGGIDSYYEYLVKGAILLEKPE-- 234
              + ++       GL+   I+  +G +T      +G   DSYYEYL+K  I   K E  
Sbjct: 423 KVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQ 482

Query: 235 LMSMFLEARQSIEKYLKKDD-----WFVWATMLRGHVTLPVFQSLESYWPGLLSL----- 284
           L+  ++EA + +  +L +        FV   +  G  +  +   L  + PG L+L     
Sbjct: 483 LLEDYVEAIEGVRTHLLRHSEPSKLTFV-GELAHGRFSAKM-DHLVCFLPGTLALGVYHG 540

Query: 285 --IGESDAAMRIIHNYHSVWRQY--GFTPEV--YNLGTGEASSSRESYP------LRPEL 332
                 + A  ++   + + RQ   G +PE+  +NL         E  P      LRPE 
Sbjct: 541 LPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPET 600

Query: 333 IESIMYLYRDTRDPILLQMGEDILRSIQHSARTPC-GYATIKDVRDHRK---EDRMESFF 388
           +ES+ YLYR T D      G +IL+S     R P  GY++I +V+D +K    D+MESFF
Sbjct: 601 VESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFF 660

Query: 389 LAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           L ET KYL+LLF                D PN   ++ L  Y+FNTEAHP+
Sbjct: 661 LGETLKYLFLLFS---------------DDPN---LLSLDAYVFNTEAHPL 693


>AL929554-19|CAH72887.1|  699|Homo sapiens mannosidase, alpha, class
           1B, member 1 protein.
          Length = 699

 Score =  206 bits (503), Expect = 2e-52
 Identities = 165/471 (35%), Positives = 240/471 (50%), Gaps = 65/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           +F HA+  Y ++A+ +DEL+P+S      W    LTLIDALDT+ I+G   EF      V
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVS-RSFSEWFGLGLTLIDALDTMWILGLRKEFEEARKWV 314

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
            +K HF+ D++V++FE+ IRI+GGLLSA+   H +G  L          LR AED   RL
Sbjct: 315 SKKLHFEKDVDVNLFESTIRILGGLLSAY---HLSGDSL---------FLRKAEDFGNRL 362

Query: 121 IAAFDTTTGMPYGTINLRSGV--PPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAY 178
           + AF T + +PY  +N+ +GV  PP  TS +  A V +  +EF  LSRLTGD  ++E   
Sbjct: 363 MPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVE 422

Query: 179 NALKALYH-HRSPIGLLGNHIDVMTGRWTAQDA-GIGGGIDSYYEYLVKGAILLEKPE-- 234
              + ++       GL+   I+  +G +T      +G   DSYYEYL+K  I   K E  
Sbjct: 423 KVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQ 482

Query: 235 LMSMFLEARQSIEKYLKKDD-----WFVWATMLRGHVTLPVFQSLESYWPGLLSL----- 284
           L+  ++EA + +  +L +        FV   +  G  +  +   L  + PG L+L     
Sbjct: 483 LLEDYVEAIEGVRTHLLRHSEPSKLTFV-GELAHGRFSAKM-DHLVCFLPGTLALGVYHG 540

Query: 285 --IGESDAAMRIIHNYHSVWRQY--GFTPEV--YNLGTGEASSSRESYP------LRPEL 332
                 + A  ++   + + RQ   G +PE+  +NL         E  P      LRPE 
Sbjct: 541 LPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPET 600

Query: 333 IESIMYLYRDTRDPILLQMGEDILRSIQHSARTPC-GYATIKDVRDHRK---EDRMESFF 388
           +ES+ YLYR T D      G +IL+S     R P  GY++I +V+D +K    D+MESFF
Sbjct: 601 VESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFF 660

Query: 389 LAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           L ET KYL+LLF                D PN   ++ L  Y+FNTEAHP+
Sbjct: 661 LGETLKYLFLLFS---------------DDPN---LLSLDAYVFNTEAHPL 693


>AL807752-35|CAI12781.1|  699|Homo sapiens mannosidase, alpha, class
           1B, member 1 protein.
          Length = 699

 Score =  206 bits (503), Expect = 2e-52
 Identities = 165/471 (35%), Positives = 240/471 (50%), Gaps = 65/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           +F HA+  Y ++A+ +DEL+P+S      W    LTLIDALDT+ I+G   EF      V
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVS-RSFSEWFGLGLTLIDALDTMWILGLRKEFEEARKWV 314

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
            +K HF+ D++V++FE+ IRI+GGLLSA+   H +G  L          LR AED   RL
Sbjct: 315 SKKLHFEKDVDVNLFESTIRILGGLLSAY---HLSGDSL---------FLRKAEDFGNRL 362

Query: 121 IAAFDTTTGMPYGTINLRSGV--PPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAY 178
           + AF T + +PY  +N+ +GV  PP  TS +  A V +  +EF  LSRLTGD  ++E   
Sbjct: 363 MPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVE 422

Query: 179 NALKALYH-HRSPIGLLGNHIDVMTGRWTAQDA-GIGGGIDSYYEYLVKGAILLEKPE-- 234
              + ++       GL+   I+  +G +T      +G   DSYYEYL+K  I   K E  
Sbjct: 423 KVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQ 482

Query: 235 LMSMFLEARQSIEKYLKKDD-----WFVWATMLRGHVTLPVFQSLESYWPGLLSL----- 284
           L+  ++EA + +  +L +        FV   +  G  +  +   L  + PG L+L     
Sbjct: 483 LLEDYVEAIEGVRTHLLRHSEPSKLTFV-GELAHGRFSAKM-DHLVCFLPGTLALGVYHG 540

Query: 285 --IGESDAAMRIIHNYHSVWRQY--GFTPEV--YNLGTGEASSSRESYP------LRPEL 332
                 + A  ++   + + RQ   G +PE+  +NL         E  P      LRPE 
Sbjct: 541 LPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPET 600

Query: 333 IESIMYLYRDTRDPILLQMGEDILRSIQHSARTPC-GYATIKDVRDHRK---EDRMESFF 388
           +ES+ YLYR T D      G +IL+S     R P  GY++I +V+D +K    D+MESFF
Sbjct: 601 VESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFF 660

Query: 389 LAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           L ET KYL+LLF                D PN   ++ L  Y+FNTEAHP+
Sbjct: 661 LGETLKYLFLLFS---------------DDPN---LLSLDAYVFNTEAHPL 693


>AF148509-1|AAF03215.1|  699|Homo sapiens alpha 1,2-mannosidase
           protein.
          Length = 699

 Score =  206 bits (503), Expect = 2e-52
 Identities = 165/471 (35%), Positives = 240/471 (50%), Gaps = 65/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           +F HA+  Y ++A+ +DEL+P+S      W    LTLIDALDT+ I+G   EF      V
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPVS-RSFSEWFGLGLTLIDALDTMWILGLRKEFEEARKWV 314

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
            +K HF+ D++V++FE+ IRI+GGLLSA+   H +G  L          LR AED   RL
Sbjct: 315 SKKLHFEKDVDVNLFESTIRILGGLLSAY---HLSGDSL---------FLRKAEDFGNRL 362

Query: 121 IAAFDTTTGMPYGTINLRSGV--PPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAY 178
           + AF T + +PY  +N+ +GV  PP  TS +  A V +  +EF  LSRLTGD  ++E   
Sbjct: 363 MPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVE 422

Query: 179 NALKALYH-HRSPIGLLGNHIDVMTGRWTAQDA-GIGGGIDSYYEYLVKGAILLEKPE-- 234
              + ++       GL+   I+  +G +T      +G   DSYYEYL+K  I   K E  
Sbjct: 423 KVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQ 482

Query: 235 LMSMFLEARQSIEKYLKKDD-----WFVWATMLRGHVTLPVFQSLESYWPGLLSL----- 284
           L+  ++EA + +  +L +        FV   +  G  +  +   L  + PG L+L     
Sbjct: 483 LLEDYVEAIEGVRTHLLRHSEPSKLTFV-GELAHGRFSAKM-DHLVCFLPGTLALGVYHG 540

Query: 285 --IGESDAAMRIIHNYHSVWRQY--GFTPEV--YNLGTGEASSSRESYP------LRPEL 332
                 + A  ++   + + RQ   G +PE+  +NL         E  P      LRPE 
Sbjct: 541 LPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPET 600

Query: 333 IESIMYLYRDTRDPILLQMGEDILRSIQHSARTPC-GYATIKDVRDHRK---EDRMESFF 388
           +ES+ YLYR T D      G +IL+S     R P  GY++I +V+D +K    D+MESFF
Sbjct: 601 VESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFF 660

Query: 389 LAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           L ET KYL+LLF                D PN   ++ L  Y+FNTEAHP+
Sbjct: 661 LGETLKYLFLLFS---------------DDPN---LLSLDAYVFNTEAHPL 693


>AF145732-1|AAD45504.1|  663|Homo sapiens endoplasmic reticulum
           alpha-mannosidase I protein.
          Length = 663

 Score =  206 bits (503), Expect = 2e-52
 Identities = 165/471 (35%), Positives = 240/471 (50%), Gaps = 65/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIV 60
           +F HA+  Y ++A+ +DEL+P+S      W    LTLIDALDT+ I+G   EF      V
Sbjct: 220 VFLHAWKGYRKFAWGHDELKPVS-RSFSEWFGLGLTLIDALDTMWILGLRKEFEEARKWV 278

Query: 61  LQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRL 120
            +K HF+ D++V++FE+ IRI+GGLLSA+   H +G  L          LR AED   RL
Sbjct: 279 SKKLHFEKDVDVNLFESTIRILGGLLSAY---HLSGDSL---------FLRKAEDFGNRL 326

Query: 121 IAAFDTTTGMPYGTINLRSGV--PPGETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAY 178
           + AF T + +PY  +N+ +GV  PP  TS +  A V +  +EF  LSRLTGD  ++E   
Sbjct: 327 MPAFRTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDKKFQEAVE 386

Query: 179 NALKALYH-HRSPIGLLGNHIDVMTGRWTAQDA-GIGGGIDSYYEYLVKGAILLEKPE-- 234
              + ++       GL+   I+  +G +T      +G   DSYYEYL+K  I   K E  
Sbjct: 387 KVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQ 446

Query: 235 LMSMFLEARQSIEKYLKKDD-----WFVWATMLRGHVTLPVFQSLESYWPGLLSL----- 284
           L+  ++EA + +  +L +        FV   +  G  +  +   L  + PG L+L     
Sbjct: 447 LLEDYVEAIEGVRTHLLRHSEPSKLTFV-GELAHGRFSAKM-DHLVCFLPGTLALGVYHG 504

Query: 285 --IGESDAAMRIIHNYHSVWRQY--GFTPEV--YNLGTGEASSSRESYP------LRPEL 332
                 + A  ++   + + RQ   G +PE+  +NL         E  P      LRPE 
Sbjct: 505 LPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPET 564

Query: 333 IESIMYLYRDTRDPILLQMGEDILRSIQHSARTPC-GYATIKDVRDHRK---EDRMESFF 388
           +ES+ YLYR T D      G +IL+S     R P  GY++I +V+D +K    D+MESFF
Sbjct: 565 VESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFF 624

Query: 389 LAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           L ET KYL+LLF                D PN   ++ L  Y+FNTEAHP+
Sbjct: 625 LGETLKYLFLLFS---------------DDPN---LLSLDAYVFNTEAHPL 657


>AL031280-2|CAI19714.1|  630|Homo sapiens mannosidase, alpha, class
           1C, member 1 protein.
          Length = 630

 Score =  198 bits (483), Expect = 5e-50
 Identities = 153/471 (32%), Positives = 237/471 (50%), Gaps = 62/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVD--TWGSYS-LTLIDALDTLAIMGNYSEFNRVV 57
           M Q A+ SY RYA   +ELRPL+ DG +   +G  S  T+ID+LDTL +M    EF    
Sbjct: 181 MMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAK 240

Query: 58  DIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVA 117
             V +  H +     S+FE NIR +GGLLSA  L+ +   +++         +RL E   
Sbjct: 241 AWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKA--------IRLGE--- 289

Query: 118 QRLIAAFDTTTGMPYGTINLRSG----VPPGETSITCTAGVGTFIIEFGTLSRLTGDPLY 173
            +L+ AF+T TG+P G ++ +SG       G +SI   A  G+  +EF  L+ L+G+ ++
Sbjct: 290 -KLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSIL--AEFGSLHLEFLHLTELSGNQVF 346

Query: 174 EEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKP 233
            E   N  K L     P GL  N +  ++G W      +GG  DS+YEYL+K  ++  K 
Sbjct: 347 AEKVRNIRKVLRKIEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKT 406

Query: 234 --ELMSMFLEARQSIEKYL--KKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGES- 288
             E  +M+ EA ++IE YL         +    RG +       L  +  G+++L  E  
Sbjct: 407 DMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDA 466

Query: 289 ---------DAAMRIIHNYHSVWRQYG--FTPEVYNLGTG-EASSSRES---YPLRPELI 333
                    + A +I    H  + +      PE +   +G EA +++ S   Y LRPE++
Sbjct: 467 KEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVV 526

Query: 334 ESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDH--RKEDRMESFFLAE 391
           ES MYL+R T +PI  + G +++ +++   RT  G++ I+DV       +++ +SFFLAE
Sbjct: 527 ESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAE 586

Query: 392 TTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPIDPN 442
           T KYLYLLF  D+                   ++ L  ++FNTEAHP+  N
Sbjct: 587 TLKYLYLLFSEDD-------------------LLSLEDWVFNTEAHPLPVN 618


>AL031280-1|CAI19713.1|  450|Homo sapiens mannosidase, alpha, class
           1C, member 1 protein.
          Length = 450

 Score =  198 bits (483), Expect = 5e-50
 Identities = 153/471 (32%), Positives = 237/471 (50%), Gaps = 62/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVD--TWGSYS-LTLIDALDTLAIMGNYSEFNRVV 57
           M Q A+ SY RYA   +ELRPL+ DG +   +G  S  T+ID+LDTL +M    EF    
Sbjct: 1   MMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAK 60

Query: 58  DIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVA 117
             V +  H +     S+FE NIR +GGLLSA  L+ +   +++         +RL E   
Sbjct: 61  AWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKA--------IRLGE--- 109

Query: 118 QRLIAAFDTTTGMPYGTINLRSG----VPPGETSITCTAGVGTFIIEFGTLSRLTGDPLY 173
            +L+ AF+T TG+P G ++ +SG       G +SI   A  G+  +EF  L+ L+G+ ++
Sbjct: 110 -KLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSIL--AEFGSLHLEFLHLTELSGNQVF 166

Query: 174 EEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKP 233
            E   N  K L     P GL  N +  ++G W      +GG  DS+YEYL+K  ++  K 
Sbjct: 167 AEKVRNIRKVLRKIEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKT 226

Query: 234 --ELMSMFLEARQSIEKYL--KKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGES- 288
             E  +M+ EA ++IE YL         +    RG +       L  +  G+++L  E  
Sbjct: 227 DMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDA 286

Query: 289 ---------DAAMRIIHNYHSVWRQYG--FTPEVYNLGTG-EASSSRES---YPLRPELI 333
                    + A +I    H  + +      PE +   +G EA +++ S   Y LRPE++
Sbjct: 287 KEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVV 346

Query: 334 ESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDH--RKEDRMESFFLAE 391
           ES MYL+R T +PI  + G +++ +++   RT  G++ I+DV       +++ +SFFLAE
Sbjct: 347 ESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAE 406

Query: 392 TTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPIDPN 442
           T KYLYLLF  D+                   ++ L  ++FNTEAHP+  N
Sbjct: 407 TLKYLYLLFSEDD-------------------LLSLEDWVFNTEAHPLPVN 438


>AF261655-1|AAF97058.1|  630|Homo sapiens 1,2-alpha-mannosidase IC
           protein.
          Length = 630

 Score =  198 bits (483), Expect = 5e-50
 Identities = 153/471 (32%), Positives = 237/471 (50%), Gaps = 62/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVD--TWGSYS-LTLIDALDTLAIMGNYSEFNRVV 57
           M Q A+ SY RYA   +ELRPL+ DG +   +G  S  T+ID+LDTL +M    EF    
Sbjct: 181 MMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAK 240

Query: 58  DIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVA 117
             V +  H +     S+FE NIR +GGLLSA  L+ +   +++         +RL E   
Sbjct: 241 AWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKA--------IRLGE--- 289

Query: 118 QRLIAAFDTTTGMPYGTINLRSG----VPPGETSITCTAGVGTFIIEFGTLSRLTGDPLY 173
            +L+ AF+T TG+P G ++ +SG       G +SI   A  G+  +EF  L+ L+G+ ++
Sbjct: 290 -KLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSIL--AEFGSLHLEFLHLTELSGNQVF 346

Query: 174 EEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKP 233
            E   N  K L     P GL  N +  ++G W      +GG  DS+YEYL+K  ++  K 
Sbjct: 347 AEKVRNIRKVLRKIEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKT 406

Query: 234 --ELMSMFLEARQSIEKYL--KKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGES- 288
             E  +M+ EA ++IE YL         +    RG +       L  +  G+++L  E  
Sbjct: 407 DMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDA 466

Query: 289 ---------DAAMRIIHNYHSVWRQYG--FTPEVYNLGTG-EASSSRES---YPLRPELI 333
                    + A +I    H  + +      PE +   +G EA +++ S   Y LRPE++
Sbjct: 467 KEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVV 526

Query: 334 ESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDH--RKEDRMESFFLAE 391
           ES MYL+R T +PI  + G +++ +++   RT  G++ I+DV       +++ +SFFLAE
Sbjct: 527 ESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAE 586

Query: 392 TTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPIDPN 442
           T KYLYLLF  D+                   ++ L  ++FNTEAHP+  N
Sbjct: 587 TLKYLYLLFSEDD-------------------LLSLEDWVFNTEAHPLPVN 618


>BC063300-1|AAH63300.1|  641|Homo sapiens mannosidase, alpha, class
           1A, member 2 protein.
          Length = 641

 Score =  194 bits (473), Expect = 9e-49
 Identities = 157/471 (33%), Positives = 237/471 (50%), Gaps = 65/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDG--VDTWGSYSL--TLIDALDTLAIMGNYSEFNRV 56
           M +HA+D+Y  Y + ++ELRP++  G   + +GS  +  T++DALDTL IMG + EF   
Sbjct: 187 MMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDG 246

Query: 57  VDIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDV 116
              +     F  +  VSVFE NIR +GGLL+A+ LS +   K++            A  +
Sbjct: 247 QRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIK------------AVQL 294

Query: 117 AQRLIAAFDTTTGMPYGTINLRSGVPPG----ETSITCTAGVGTFIIEFGTLSRLTGDPL 172
           A++L+ AF+T TG+P+  +NL+SGV           +  A  GT  +EF  LS LTGD  
Sbjct: 295 AEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLT 354

Query: 173 YEEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEK 232
           Y +   +  K L     P GL  N+++  TGRW      +GG  DS+YEYL+K  ++ +K
Sbjct: 355 YYKKVMHIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDK 414

Query: 233 P--ELMSMFLEARQSIEKYLKKDD----WFVWATMLRGHVTLPVFQSLESYWPGLLSLIG 286
              E   M+ +A ++IEK+L K       F+      GH+   +   L  +  G+ +L  
Sbjct: 415 TDHEARKMYDDAIEAIEKHLIKKSRGGLTFI-GEWKNGHLEKKM-GHLACFAGGMFALGA 472

Query: 287 ESDAAMRIIHNY-------HSVWRQYGFT-----PEVYNL-GTGEASSSRES---YPLRP 330
           +   A +  H          +    Y  T     PE +   G  EA + R++   Y LRP
Sbjct: 473 DGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRP 532

Query: 331 ELIESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDH--RKEDRMESFF 388
           E+IE+  YL+R T DP   Q G +   +I+   R   G++ +KDV       +D  +SFF
Sbjct: 533 EVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFF 592

Query: 389 LAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           LAET KYLYLLF                   +G+ ++ L  ++FNTEAHP+
Sbjct: 593 LAETLKYLYLLF-------------------SGDDLLPLDHWVFNTEAHPL 624


>AL358072-1|CAH71079.1|  641|Homo sapiens mannosidase, alpha, class
           1A, member 2 protein.
          Length = 641

 Score =  194 bits (473), Expect = 9e-49
 Identities = 157/471 (33%), Positives = 237/471 (50%), Gaps = 65/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDG--VDTWGSYSL--TLIDALDTLAIMGNYSEFNRV 56
           M +HA+D+Y  Y + ++ELRP++  G   + +GS  +  T++DALDTL IMG + EF   
Sbjct: 187 MMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDG 246

Query: 57  VDIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDV 116
              +     F  +  VSVFE NIR +GGLL+A+ LS +   K++            A  +
Sbjct: 247 QRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIK------------AVQL 294

Query: 117 AQRLIAAFDTTTGMPYGTINLRSGVPPG----ETSITCTAGVGTFIIEFGTLSRLTGDPL 172
           A++L+ AF+T TG+P+  +NL+SGV           +  A  GT  +EF  LS LTGD  
Sbjct: 295 AEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLT 354

Query: 173 YEEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEK 232
           Y +   +  K L     P GL  N+++  TGRW      +GG  DS+YEYL+K  ++ +K
Sbjct: 355 YYKKVMHIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDK 414

Query: 233 P--ELMSMFLEARQSIEKYLKKDD----WFVWATMLRGHVTLPVFQSLESYWPGLLSLIG 286
              E   M+ +A ++IEK+L K       F+      GH+   +   L  +  G+ +L  
Sbjct: 415 TDHEARKMYDDAIEAIEKHLIKKSRGGLTFI-GEWKNGHLEKKM-GHLACFAGGMFALGA 472

Query: 287 ESDAAMRIIHNY-------HSVWRQYGFT-----PEVYNL-GTGEASSSRES---YPLRP 330
           +   A +  H          +    Y  T     PE +   G  EA + R++   Y LRP
Sbjct: 473 DGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRP 532

Query: 331 ELIESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDH--RKEDRMESFF 388
           E+IE+  YL+R T DP   Q G +   +I+   R   G++ +KDV       +D  +SFF
Sbjct: 533 EVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFF 592

Query: 389 LAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           LAET KYLYLLF                   +G+ ++ L  ++FNTEAHP+
Sbjct: 593 LAETLKYLYLLF-------------------SGDDLLPLDHWVFNTEAHPL 624


>AL157902-1|CAI22315.1|  641|Homo sapiens mannosidase, alpha, class
           1A, member 2 protein.
          Length = 641

 Score =  194 bits (473), Expect = 9e-49
 Identities = 157/471 (33%), Positives = 237/471 (50%), Gaps = 65/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDG--VDTWGSYSL--TLIDALDTLAIMGNYSEFNRV 56
           M +HA+D+Y  Y + ++ELRP++  G   + +GS  +  T++DALDTL IMG + EF   
Sbjct: 187 MMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDG 246

Query: 57  VDIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDV 116
              +     F  +  VSVFE NIR +GGLL+A+ LS +   K++            A  +
Sbjct: 247 QRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIK------------AVQL 294

Query: 117 AQRLIAAFDTTTGMPYGTINLRSGVPPG----ETSITCTAGVGTFIIEFGTLSRLTGDPL 172
           A++L+ AF+T TG+P+  +NL+SGV           +  A  GT  +EF  LS LTGD  
Sbjct: 295 AEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLT 354

Query: 173 YEEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEK 232
           Y +   +  K L     P GL  N+++  TGRW      +GG  DS+YEYL+K  ++ +K
Sbjct: 355 YYKKVMHIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDK 414

Query: 233 P--ELMSMFLEARQSIEKYLKKDD----WFVWATMLRGHVTLPVFQSLESYWPGLLSLIG 286
              E   M+ +A ++IEK+L K       F+      GH+   +   L  +  G+ +L  
Sbjct: 415 TDHEARKMYDDAIEAIEKHLIKKSRGGLTFI-GEWKNGHLEKKM-GHLACFAGGMFALGA 472

Query: 287 ESDAAMRIIHNY-------HSVWRQYGFT-----PEVYNL-GTGEASSSRES---YPLRP 330
           +   A +  H          +    Y  T     PE +   G  EA + R++   Y LRP
Sbjct: 473 DGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRP 532

Query: 331 ELIESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDH--RKEDRMESFF 388
           E+IE+  YL+R T DP   Q G +   +I+   R   G++ +KDV       +D  +SFF
Sbjct: 533 EVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFF 592

Query: 389 LAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           LAET KYLYLLF                   +G+ ++ L  ++FNTEAHP+
Sbjct: 593 LAETLKYLYLLF-------------------SGDDLLPLDHWVFNTEAHPL 624


>AF027156-1|AAC26169.1|  641|Homo sapiens alpha 1,2-mannosidase IB
           protein.
          Length = 641

 Score =  194 bits (473), Expect = 9e-49
 Identities = 157/471 (33%), Positives = 237/471 (50%), Gaps = 65/471 (13%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDG--VDTWGSYSL--TLIDALDTLAIMGNYSEFNRV 56
           M +HA+D+Y  Y + ++ELRP++  G   + +GS  +  T++DALDTL IMG + EF   
Sbjct: 187 MMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDG 246

Query: 57  VDIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDV 116
              +     F  +  VSVFE NIR +GGLL+A+ LS +   K++            A  +
Sbjct: 247 QRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIK------------AVQL 294

Query: 117 AQRLIAAFDTTTGMPYGTINLRSGVPPG----ETSITCTAGVGTFIIEFGTLSRLTGDPL 172
           A++L+ AF+T TG+P+  +NL+SGV           +  A  GT  +EF  LS LTGD  
Sbjct: 295 AEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLT 354

Query: 173 YEEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEK 232
           Y +   +  K L     P GL  N+++  TGRW      +GG  DS+YEYL+K  ++ +K
Sbjct: 355 YYKKVMHIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDK 414

Query: 233 P--ELMSMFLEARQSIEKYLKKDD----WFVWATMLRGHVTLPVFQSLESYWPGLLSLIG 286
              E   M+ +A ++IEK+L K       F+      GH+   +   L  +  G+ +L  
Sbjct: 415 TDHEARKMYDDAIEAIEKHLIKKSRGGLTFI-GEWKNGHLEKKM-GHLACFAGGMFALGA 472

Query: 287 ESDAAMRIIHNY-------HSVWRQYGFT-----PEVYNL-GTGEASSSRES---YPLRP 330
           +   A +  H          +    Y  T     PE +   G  EA + R++   Y LRP
Sbjct: 473 DGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRP 532

Query: 331 ELIESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDH--RKEDRMESFF 388
           E+IE+  YL+R T DP   Q G +   +I+   R   G++ +KDV       +D  +SFF
Sbjct: 533 EVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFF 592

Query: 389 LAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           LAET KYLYLLF                   +G+ ++ L  ++FNTEAHP+
Sbjct: 593 LAETLKYLYLLF-------------------SGDDLLPLDHWVFNTEAHPL 624


>AL078600-1|CAB75695.2|  653|Homo sapiens mannosidase, alpha, class
           1A, member 1 protein.
          Length = 653

 Score =  190 bits (463), Expect = 1e-47
 Identities = 133/435 (30%), Positives = 223/435 (51%), Gaps = 41/435 (9%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDT--WGSYS-LTLIDALDTLAIMGNYSEFNRVV 57
           M +HA+++Y  YA+  +EL+P+S  G  +  +G+    T++DALDTL IM    EF    
Sbjct: 202 MMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKHEFEEAK 261

Query: 58  DIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVA 117
             V +   F+ +  +SVFE NIR VGGLLSA+ LS +   +            + A ++ 
Sbjct: 262 SWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEIFR------------KKAVELG 309

Query: 118 QRLIAAFDTTTGMPYGTINLRSGV----PPGETSITCTAGVGTFIIEFGTLSRLTGDPLY 173
            +L+ AF T +G+P+  +N++SG+    P      +  A  GT  +EF  LS L+G+P++
Sbjct: 310 VKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLSGNPIF 369

Query: 174 EEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKP 233
            E   N    L     P GL  N+++  +G+W      +GG  DS+YEYL+K  ++ +K 
Sbjct: 370 AEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKAWLMSDKT 429

Query: 234 EL--MSMFLEARQSIEKYL--KKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGES- 288
           +L    M+ +A Q+IE +L  K      +    +G +       L  +  G+ +L  ++ 
Sbjct: 430 DLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADAA 489

Query: 289 ---------DAAMRIIHNYHSVWRQ--YGFTPEVYNLGTG-EASSSRES---YPLRPELI 333
                    +    I    H  + +      PE +    G EA ++R++   Y LRPE++
Sbjct: 490 PEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEKYYILRPEVM 549

Query: 334 ESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDV--RDHRKEDRMESFFLAE 391
           E+ MY++R T DP   +   + + ++++  R   GY+ ++DV       +D  +SFFLAE
Sbjct: 550 ETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDDVQQSFFLAE 609

Query: 392 TTKYLYLLFDPDNFI 406
           T KYLYL+F  D+ +
Sbjct: 610 TLKYLYLIFSDDDLL 624


>AL022722-2|CAI20315.1|  653|Homo sapiens mannosidase, alpha, class
           1A, member 1 protein.
          Length = 653

 Score =  190 bits (463), Expect = 1e-47
 Identities = 133/435 (30%), Positives = 223/435 (51%), Gaps = 41/435 (9%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDT--WGSYS-LTLIDALDTLAIMGNYSEFNRVV 57
           M +HA+++Y  YA+  +EL+P+S  G  +  +G+    T++DALDTL IM    EF    
Sbjct: 202 MMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKHEFEEAK 261

Query: 58  DIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVA 117
             V +   F+ +  +SVFE NIR VGGLLSA+ LS +   +            + A ++ 
Sbjct: 262 SWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEIFR------------KKAVELG 309

Query: 118 QRLIAAFDTTTGMPYGTINLRSGV----PPGETSITCTAGVGTFIIEFGTLSRLTGDPLY 173
            +L+ AF T +G+P+  +N++SG+    P      +  A  GT  +EF  LS L+G+P++
Sbjct: 310 VKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLSGNPIF 369

Query: 174 EEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKP 233
            E   N    L     P GL  N+++  +G+W      +GG  DS+YEYL+K  ++ +K 
Sbjct: 370 AEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKAWLMSDKT 429

Query: 234 EL--MSMFLEARQSIEKYL--KKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGES- 288
           +L    M+ +A Q+IE +L  K      +    +G +       L  +  G+ +L  ++ 
Sbjct: 430 DLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADAA 489

Query: 289 ---------DAAMRIIHNYHSVWRQ--YGFTPEVYNLGTG-EASSSRES---YPLRPELI 333
                    +    I    H  + +      PE +    G EA ++R++   Y LRPE++
Sbjct: 490 PEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEKYYILRPEVM 549

Query: 334 ESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDV--RDHRKEDRMESFFLAE 391
           E+ MY++R T DP   +   + + ++++  R   GY+ ++DV       +D  +SFFLAE
Sbjct: 550 ETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDDVQQSFFLAE 609

Query: 392 TTKYLYLLFDPDNFI 406
           T KYLYL+F  D+ +
Sbjct: 610 TLKYLYLIFSDDDLL 624


>X74837-1|CAA52831.1|  625|Homo sapiens Man9-mannosidase protein.
          Length = 625

 Score =  188 bits (457), Expect = 8e-47
 Identities = 140/437 (32%), Positives = 229/437 (52%), Gaps = 45/437 (10%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDT--WGSYS-LTLIDALDTLAIMGNYSEFNRVV 57
           M +HA+++Y  YA+  +EL+P+S  G  +  +G+    T++DALDTL IM    EF    
Sbjct: 174 MMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKHEFEEAK 233

Query: 58  DIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVA 117
             V +   F+ +  +SVFE NIR VGGLLSA+ LS +   +            + A ++ 
Sbjct: 234 SWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEIFR------------KKAVELG 281

Query: 118 QRLIAAFDTTTGMPYGTINLRSGV----PPGETSITCTAGVGTFIIEFGTLSRLTGDPLY 173
            +L+ AF T +G+P+  +N++SG+    P      +  A  GT  +EF  LS L+G+P++
Sbjct: 282 VKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLSGNPIF 341

Query: 174 EEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKP 233
            E   N    L     P GL  N+++  +G+W      +GG  DS+YEYL+K  ++ +K 
Sbjct: 342 AEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKAWLMSDKT 401

Query: 234 EL--MSMFLEARQSIEKYL--KKDDWFV----WATML----RGHVTL---PVFQ-SLESY 277
           +L    M+ +A Q+IE +L  K          W   L     GH+T     +F    ++ 
Sbjct: 402 DLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKRGLLEHKMGHLTCFAGGMFALGADAA 461

Query: 278 WPGLLSLIGESDAAM-RIIH-NYHSVWRQYGFTPEVYNLGTG-EASSSRES---YPLRPE 331
             G+     E  A + R  H +Y+  + + G  PE +    G EA ++R++   Y LRPE
Sbjct: 462 PEGMAQHYLELGAEIARTCHESYNRTFMKLG--PEAFRFDGGVEAIATRQNEKYYILRPE 519

Query: 332 LIESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDV--RDHRKEDRMESFFL 389
           ++E+ MY++R T DP   +   + + ++++  R   GY+ ++DV       +D  +SFFL
Sbjct: 520 VMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDDVQQSFFL 579

Query: 390 AETTKYLYLLFDPDNFI 406
           AET KYLYL+F  D+ +
Sbjct: 580 AETLKYLYLIFSDDDLL 596


>AB209275-1|BAD92512.1|  482|Homo sapiens mannosidase, alpha, class
           1C, member 1 variant protein.
          Length = 482

 Score =  180 bits (438), Expect = 2e-44
 Identities = 137/423 (32%), Positives = 215/423 (50%), Gaps = 43/423 (10%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVD--TWGSYS-LTLIDALDTLAIMGNYSEFNRVV 57
           M Q A+ SY RYA   +ELRPL+ DG +   +G  S  T+ID+LDTL +M    EF    
Sbjct: 73  MMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAK 132

Query: 58  DIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVA 117
             V +  H +     S+FE NIR +GGLLSA  L+ +   +++         +RL E   
Sbjct: 133 AWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKA--------IRLGE--- 181

Query: 118 QRLIAAFDTTTGMPYGTINLRSG----VPPGETSITCTAGVGTFIIEFGTLSRLTGDPLY 173
            +L+ AF+T TG+P G ++ +SG       G +SI   A  G+  +EF  L+ L+G+ ++
Sbjct: 182 -KLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSIL--AEFGSLHLEFLHLTELSGNQVF 238

Query: 174 EEVAYNALKALYHHRSPIGLLGNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKP 233
            E   N  K L     P GL  N +  ++G W      +GG  DS+YEYL+K  ++  K 
Sbjct: 239 AEKVRNIRKVLRKIEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKT 298

Query: 234 --ELMSMFLEARQSIEKYL--KKDDWFVWATMLRGHVTLPVFQSLESYWPGLLSLIGES- 288
             E  +M+ EA ++IE YL         +    RG +       L  +  G+++L  E  
Sbjct: 299 DMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDA 358

Query: 289 ---------DAAMRIIHNYHSVWRQYG--FTPEVYNLGTG-EASSSRES---YPLRPELI 333
                    + A +I    H  + +      PE +   +G EA +++ S   Y LRPE++
Sbjct: 359 KEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVV 418

Query: 334 ESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGYATIKDVRDH--RKEDRMESFFLAE 391
           ES MYL+R T +PI  + G +++ +++   RT  G++ I+DV       +++ +SFFLAE
Sbjct: 419 ESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAE 478

Query: 392 TTK 394
           T K
Sbjct: 479 TLK 481


>BC105586-1|AAI05587.1|  242|Homo sapiens EDEM3 protein protein.
          Length = 242

 Score =  177 bits (430), Expect = 1e-43
 Identities = 99/225 (44%), Positives = 133/225 (59%), Gaps = 6/225 (2%)

Query: 21  PLSCDGVDTWGSYSLTLIDALDTLAIMGNYSEFNRVVDIVLQKRHFDADINVSVFETNIR 80
           P   D  D  G +SLTLID+LDTL ++    EF   V  VL+  + D D+ VSVFETNIR
Sbjct: 14  PSRGDVDDALGKFSLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIR 73

Query: 81  IVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRLIAAFDTTTGMPYGTINLRSG 140
           ++GGLL  H L+     K E     N  LL++A+ +  +L+ AF+TT+G+PY  INL+ G
Sbjct: 74  VLGGLLGGHSLAIMLKEKGEYMQWYNDELLQMAKQLGYKLLPAFNTTSGLPYPRINLKFG 133

Query: 141 V--PPGETSI---TCTAGVGTFIIEFGTLSRLTGDPLYEEVAYNALKALYHHRS-PIGLL 194
           +  P   T     TCTA  GT I+EF  LSR TG  ++EE A  AL  L+  R     L+
Sbjct: 134 IRKPEARTGTETDTCTACAGTLILEFAALSRFTGATIFEEYARKALDFLWEKRQRSSNLV 193

Query: 195 GNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKPELMSMF 239
           G  I++ TG W  +D+G+G GIDSYYEYL+K  +LL     +  F
Sbjct: 194 GVTINIHTGDWVRKDSGVGAGIDSYYEYLLKAYVLLGDDSFLERF 238


>AK023308-1|BAB14518.1|  618|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13246 fis, clone OVARC1000682, highly similar to
           PROCESSING ALPHA-1,2-MANNOSIDASE (EC 3.2.1.-). ).
          Length = 618

 Score =  128 bits (309), Expect = 6e-29
 Identities = 86/233 (36%), Positives = 125/233 (53%), Gaps = 19/233 (8%)

Query: 27  VDTWGSY-SLTLIDALDTLAIMGNYSEFNRVVDIVLQKRHFDADINVSVFETNIRIVGGL 85
           +DT  S    T++DALDTL IMG + EF      +     F  +  VSVFE NIR +GGL
Sbjct: 6   IDTGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGL 65

Query: 86  LSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRLIAAFDTTTGMPYGTINLRSGVPPG- 144
           L+A+ LS +   K++            A  +A++L+ AF+T TG+P+  +NL+SGV    
Sbjct: 66  LAAYYLSGEEIFKIK------------AVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNW 113

Query: 145 ---ETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAYNALKALYHHRSPIGLLGNHIDVM 201
                  +  A  GT  +EF  LS LTGD  Y +   +  K L     P GL  N+++  
Sbjct: 114 GWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMDRPNGLYPNYLNPR 173

Query: 202 TGRWTAQDAGIGGGIDSYYEYLVKGAILLEKP--ELMSMFLEARQSIEKYLKK 252
           TGRW      +GG  DS+YEYL+K  ++ +K   E   M+ +A ++IEK+L K
Sbjct: 174 TGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLIK 226


>AL358072-2|CAH71080.1|  343|Homo sapiens mannosidase, alpha, class
           1A, member 2 protein.
          Length = 343

 Score =  126 bits (304), Expect = 3e-28
 Identities = 110/344 (31%), Positives = 167/344 (48%), Gaps = 42/344 (12%)

Query: 79  IRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRLIAAFDTTTGMPYGTINLR 138
           IR +GGLL+A+ LS +   K++            A  +A++L+ AF+T TG+P+  +NL+
Sbjct: 1   IRFIGGLLAAYYLSGEEIFKIK------------AVQLAEKLLPAFNTPTGIPWAMVNLK 48

Query: 139 SGVPPG----ETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAYNALKALYHHRSPIGLL 194
           SGV           +  A  GT  +EF  LS LTGD  Y +   +  K L     P GL 
Sbjct: 49  SGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMDRPNGLY 108

Query: 195 GNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKP--ELMSMFLEARQSIEKYLKK 252
            N+++  TGRW      +GG  DS+YEYL+K  ++ +K   E   M+ +A ++IEK+L K
Sbjct: 109 PNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLIK 168

Query: 253 DD----WFVWATMLRGHVTLPVFQSLESYWPGLLSLIGESDAAMRIIHNY-------HSV 301
                  F+      GH+   +   L  +  G+ +L  +   A +  H          + 
Sbjct: 169 KSRGGLTFI-GEWKNGHLEKKM-GHLACFAGGMFALGADGSRADKAGHYLELGAEIARTC 226

Query: 302 WRQYGFT-----PEVYNL-GTGEASSSRES---YPLRPELIESIMYLYRDTRDPILLQMG 352
              Y  T     PE +   G  EA + R++   Y LRPE+IE+  YL+R T DP   Q G
Sbjct: 227 HESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWG 286

Query: 353 EDILRSIQHSARTPCGYATIKDVRDH--RKEDRMESFFLAETTK 394
            +   +I+   R   G++ +KDV       +D  +SFFLAET K
Sbjct: 287 WEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLK 330


>AL157902-4|CAI22318.1|  343|Homo sapiens mannosidase, alpha, class
           1A, member 2 protein.
          Length = 343

 Score =  126 bits (304), Expect = 3e-28
 Identities = 110/344 (31%), Positives = 167/344 (48%), Gaps = 42/344 (12%)

Query: 79  IRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVAQRLIAAFDTTTGMPYGTINLR 138
           IR +GGLL+A+ LS +   K++            A  +A++L+ AF+T TG+P+  +NL+
Sbjct: 1   IRFIGGLLAAYYLSGEEIFKIK------------AVQLAEKLLPAFNTPTGIPWAMVNLK 48

Query: 139 SGVPPG----ETSITCTAGVGTFIIEFGTLSRLTGDPLYEEVAYNALKALYHHRSPIGLL 194
           SGV           +  A  GT  +EF  LS LTGD  Y +   +  K L     P GL 
Sbjct: 49  SGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMDRPNGLY 108

Query: 195 GNHIDVMTGRWTAQDAGIGGGIDSYYEYLVKGAILLEKP--ELMSMFLEARQSIEKYLKK 252
            N+++  TGRW      +GG  DS+YEYL+K  ++ +K   E   M+ +A ++IEK+L K
Sbjct: 109 PNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLIK 168

Query: 253 DD----WFVWATMLRGHVTLPVFQSLESYWPGLLSLIGESDAAMRIIHNY-------HSV 301
                  F+      GH+   +   L  +  G+ +L  +   A +  H          + 
Sbjct: 169 KSRGGLTFI-GEWKNGHLEKKM-GHLACFAGGMFALGADGSRADKAGHYLELGAEIARTC 226

Query: 302 WRQYGFT-----PEVYNL-GTGEASSSRES---YPLRPELIESIMYLYRDTRDPILLQMG 352
              Y  T     PE +   G  EA + R++   Y LRPE+IE+  YL+R T DP   Q G
Sbjct: 227 HESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWG 286

Query: 353 EDILRSIQHSARTPCGYATIKDVRDH--RKEDRMESFFLAETTK 394
            +   +I+   R   G++ +KDV       +D  +SFFLAET K
Sbjct: 287 WEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLK 330


>AF053621-1|AAC26200.1|  358|Homo sapiens alpha 1,2-mannosidase IB
           protein.
          Length = 358

 Score =  102 bits (244), Expect = 5e-21
 Identities = 68/181 (37%), Positives = 101/181 (55%), Gaps = 20/181 (11%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDG--VDTWGSYSL--TLIDALDTLAIMGNYSEFNRV 56
           M +HA+D+Y  Y + ++ELRP++  G   + +GS  +  T++DALDTL IMG + EF   
Sbjct: 187 MMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDG 246

Query: 57  VDIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDV 116
              +     F  +  VSVFE NIR +GGLL+A+ LS +   K++            A  +
Sbjct: 247 QRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIK------------AVQL 294

Query: 117 AQRLIAAFDTTTGMPYGTINLRSGVPP----GETSITCTAGVGTFIIEFGTLSRLTGDPL 172
           A++L+ AF+T TG+P+  +NL+SGV           +  A  GT  +EF  LS LTGD  
Sbjct: 295 AEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLT 354

Query: 173 Y 173
           Y
Sbjct: 355 Y 355


>AF053626-1|AAC26201.1|  251|Homo sapiens alpha 1,2-mannosidase IB
           protein.
          Length = 251

 Score = 81.8 bits (193), Expect = 7e-15
 Identities = 79/252 (31%), Positives = 121/252 (48%), Gaps = 45/252 (17%)

Query: 212 IGGGIDSYYEYLVKGAILLEKP--ELMSMFLEARQSIEKYLKKDD----WFVWATMLRGH 265
           +GG  DS+YEYL+K  ++ +K   E   M+ +A ++IEK+L K       F+      GH
Sbjct: 4   VGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFI-GEWKNGH 62

Query: 266 VTLPVFQSLESYWPGLLSLIGESDAAMRIIHNYH-------SVWRQYGFT-----PEVYN 313
           +   +   L  +  G+ +L  +   A +  H          +    Y  T     PE + 
Sbjct: 63  LEKKMGH-LACFAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFK 121

Query: 314 L-GTGEASSSRES---YPLRPELIESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCGY 369
             G  EA + R++   Y LRPE+IE+  YL+R T DP   Q G +   +I+   R   G+
Sbjct: 122 FDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGF 181

Query: 370 ATIKDVRDH--RKEDRMESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDL 427
           + +KDV       +D  +SFFLAET KYLYLLF                   +G+ ++ L
Sbjct: 182 SGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLF-------------------SGDDLLPL 222

Query: 428 GGYIFNTEAHPI 439
             ++FNTEAHP+
Sbjct: 223 DHWVFNTEAHPL 234


>AK074559-1|BAC11060.1|  178|Homo sapiens .2.1.113).  protein.
          Length = 178

 Score = 81.4 bits (192), Expect = 1e-14
 Identities = 51/116 (43%), Positives = 66/116 (56%), Gaps = 22/116 (18%)

Query: 328 LRPELIESIMYLYRDTRDPILLQMGEDILRSIQHSARTPCG-YATIKDVRDHRK---EDR 383
           LRPE +ES+ YLYR T D      G +IL+S     R P G Y++I +V+D +K    D+
Sbjct: 75  LRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDK 134

Query: 384 MESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           MESFFL ET KYL+LLF                D PN   ++ L  Y+FNTEAHP+
Sbjct: 135 MESFFLGETLKYLFLLFS---------------DDPN---LLSLDAYVFNTEAHPL 172


>AB209276-1|BAD92513.1|  185|Homo sapiens alpha 1,2-mannosidase
           variant protein.
          Length = 185

 Score = 79.8 bits (188), Expect = 3e-14
 Identities = 50/116 (43%), Positives = 65/116 (56%), Gaps = 22/116 (18%)

Query: 328 LRPELIESIMYLYRDTRDPILLQMGEDILRSIQHSARTPC-GYATIKDVRDHRK---EDR 383
           LRPE +ES+ YLYR T D      G +IL+S     R P  GY++I + +D +K    D+
Sbjct: 82  LRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNAQDPQKPEPRDK 141

Query: 384 MESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVVDLGGYIFNTEAHPI 439
           MESFFL ET KYL+LLF                D PN   ++ L  Y+FNTEAHP+
Sbjct: 142 MESFFLGETLKYLFLLFS---------------DDPN---LLSLDAYVFNTEAHPL 179


>BC065827-1|AAH65827.1|  367|Homo sapiens MAN1A1 protein protein.
          Length = 367

 Score = 79.0 bits (186), Expect = 5e-14
 Identities = 50/141 (35%), Positives = 81/141 (57%), Gaps = 15/141 (10%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDGVDT--WGSYS-LTLIDALDTLAIMGNYSEFNRVV 57
           M +HA+++Y  YA+  +EL+P+S  G  +  +G+    T++DALDTL IM    EF    
Sbjct: 225 MMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKHEFEEAK 284

Query: 58  DIVLQKRHFDADINVSVFETNIRIVGGLLSAHLLSHKTGMKLEPGWPCNGPLLRLAEDVA 117
             V +   F+ +  +SVFE NIR VGGLLSA+ LS   G ++           + A ++ 
Sbjct: 285 SWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS---GEEI---------FRKKAVELG 332

Query: 118 QRLIAAFDTTTGMPYGTINLR 138
            +L+ AF T +G+P+  +N++
Sbjct: 333 VKLLPAFHTPSGIPWALLNMK 353


>AL157902-2|CAI22316.1|  203|Homo sapiens mannosidase, alpha, class
           1A, member 2 protein.
          Length = 203

 Score = 71.7 bits (168), Expect = 8e-12
 Identities = 51/137 (37%), Positives = 73/137 (53%), Gaps = 25/137 (18%)

Query: 309 PEVYNL-GTGEASSSRES---YPLRPELIESIMYLYRDTRDPILLQMGEDILRSIQHSAR 364
           PE +   G  EA + R++   Y LRPE+IE+  YL+R T DP   Q G +   +I+   R
Sbjct: 73  PESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCR 132

Query: 365 TPCGYATIKDVRDH--RKEDRMESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGE 422
              G++ +KDV       +D  +SFFLAET KYLYLLF                   +G+
Sbjct: 133 VNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLF-------------------SGD 173

Query: 423 CVVDLGGYIFNTEAHPI 439
            ++ L  ++FNTEAHP+
Sbjct: 174 DLLPLDHWVFNTEAHPL 190


>AL929554-1|CAH72871.2|  329|Homo sapiens mannosidase, alpha, class
           1B, member 1 protein.
          Length = 329

 Score = 58.4 bits (135), Expect = 8e-08
 Identities = 66/231 (28%), Positives = 102/231 (44%), Gaps = 26/231 (11%)

Query: 159 IEFGTLSRLTGDPLYEEVAYNALKALYH-HRSPIGLLGNHIDVMTGRWTAQDA-GIGGGI 216
           +EF  LSRLTGD  ++E      + ++       GL+   I+  +G +T      +G   
Sbjct: 1   LEFRELSRLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARA 60

Query: 217 DSYYEYLVKGAILLEKPE--LMSMFLEARQSIEKYLKKDDWFVWATMLRGHVTLPVFQS- 273
           DSYYEYL+K  I   K E  L+  ++EA + +  +L +       T + G +    F + 
Sbjct: 61  DSYYEYLLKQWIQGGKQETQLLEDYVEAIEGVRTHLLRHSEPSKLTFV-GELAHGRFSAK 119

Query: 274 ---LESYWPGLLSL-------IGESDAAMRIIHNYHSVWRQY--GFTPEV--YNLGTGEA 319
              L  + PG L+L           + A  ++   + + RQ   G +PE+  +NL     
Sbjct: 120 MDHLVCFLPGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPG 179

Query: 320 SSSRESYP------LRPELIESIMYLYRDTRDPILLQMGEDILRSIQHSAR 364
               E  P      LRPE +ES+ YLYR T D      G +IL+S     R
Sbjct: 180 RRDVEVKPADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTR 230


>AL096819-2|CAI21740.1|  155|Homo sapiens ER degradation enhancer,
           mannosidase alpha-like 3 protein.
          Length = 155

 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 28/59 (47%), Positives = 36/59 (61%), Gaps = 12/59 (20%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDG------------VDTWGSYSLTLIDALDTLAIM 47
           MF HAY +Y+ +AYP DEL PL+C G             D  G +SLTLID+LDTL ++
Sbjct: 59  MFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLVVI 117


>AK023095-1|BAB14402.1|  155|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13033 fis, clone NT2RP3001126. ).
          Length = 155

 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 28/59 (47%), Positives = 36/59 (61%), Gaps = 12/59 (20%)

Query: 1   MFQHAYDSYLRYAYPYDELRPLSCDG------------VDTWGSYSLTLIDALDTLAIM 47
           MF HAY +Y+ +AYP DEL PL+C G             D  G +SLTLID+LDTL ++
Sbjct: 59  MFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDALGKFSLTLIDSLDTLEVI 117


>AL157902-3|CAI22317.1|   97|Homo sapiens mannosidase, alpha, class
           1A, member 2 protein.
          Length = 97

 Score = 41.9 bits (94), Expect = 0.007
 Identities = 28/74 (37%), Positives = 40/74 (54%), Gaps = 21/74 (28%)

Query: 368 GYATIKDVRDHRK--EDRMESFFLAETTKYLYLLFDPDNFIHNPGVRGTVIDTPNGECVV 425
           G++ +KDV       +D  +SFFLAET KYLYLLF                   +G+ ++
Sbjct: 9   GFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLF-------------------SGDDLL 49

Query: 426 DLGGYIFNTEAHPI 439
            L  ++FNTEAHP+
Sbjct: 50  PLDHWVFNTEAHPL 63


>BC139779-1|AAI39780.1|  606|Homo sapiens zinc finger protein 652
           protein.
          Length = 606

 Score = 37.5 bits (83), Expect = 0.16
 Identities = 39/146 (26%), Positives = 61/146 (41%), Gaps = 10/146 (6%)

Query: 508 EPKERSDENEPEQNQVLIKTESRTGYVNLDG-TERENANESNLSDLVKETINKYYNDTIN 566
           E +E SD+ E E+ +V  K E     VNL+  T   +  E  +S   KET        + 
Sbjct: 95  EDRENSDDTEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKET------PVLK 148

Query: 567 AETQENVKHSAEEPTAGSSQTVEVDDIIVPEKSEVQLPSVT--KTKEVMNMLPKVIQDFL 624
             ++E  + S EE T  S+   E +     EK  V+  SVT  +T+   ++         
Sbjct: 149 TSSEEEEEESEEEATDDSNDYGENEKQKKKEKI-VEKVSVTQRRTRRAASVAAATTSPTP 207

Query: 625 NSDWKSKPKCEPQKMLERIRREQKYP 650
            +    +   EP K  +R  +E K P
Sbjct: 208 RTTRGRRKSVEPPKRKKRATKEPKAP 233


>AB023141-1|BAA76768.2|  617|Homo sapiens KIAA0924 protein protein.
          Length = 617

 Score = 37.5 bits (83), Expect = 0.16
 Identities = 39/146 (26%), Positives = 61/146 (41%), Gaps = 10/146 (6%)

Query: 508 EPKERSDENEPEQNQVLIKTESRTGYVNLDG-TERENANESNLSDLVKETINKYYNDTIN 566
           E +E SD+ E E+ +V  K E     VNL+  T   +  E  +S   KET        + 
Sbjct: 106 EDRENSDDTEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKET------PVLK 159

Query: 567 AETQENVKHSAEEPTAGSSQTVEVDDIIVPEKSEVQLPSVT--KTKEVMNMLPKVIQDFL 624
             ++E  + S EE T  S+   E +     EK  V+  SVT  +T+   ++         
Sbjct: 160 TSSEEEEEESEEEATDDSNDYGENEKQKKKEKI-VEKVSVTQRRTRRAASVAAATTSPTP 218

Query: 625 NSDWKSKPKCEPQKMLERIRREQKYP 650
            +    +   EP K  +R  +E K P
Sbjct: 219 RTTRGRRKSVEPPKRKKRATKEPKAP 244


>AK090938-1|BAC03551.1|  208|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33619 fis, clone BRAMY2020427. ).
          Length = 208

 Score = 35.1 bits (77), Expect = 0.83
 Identities = 25/127 (19%), Positives = 61/127 (48%), Gaps = 3/127 (2%)

Query: 518 PEQNQVLIKTESRTGYVNLDGTERENANESNLSDLVKETINKYYNDTINAETQENVKHSA 577
           PE+ +  I+ E+ T    + GTE+ENA E     ++   +++ ++  + A   +    + 
Sbjct: 40  PEERKTEIERETETESETVIGTEKENAPERERGSVI-TVLHQVFSTGLLAMKNDTDTGNM 98

Query: 578 EEPTAGSSQTVE--VDDIIVPEKSEVQLPSVTKTKEVMNMLPKVIQDFLNSDWKSKPKCE 635
           ++     ++ VE   +DI   +    + P ++  + ++++  KV ++ +  D  +K   E
Sbjct: 99  QKEVMSVTEQVEKKKNDIEKDDTGRKRKPDISLLEVIVDVAMKVKKEIVTGDTNTKNLKE 158

Query: 636 PQKMLER 642
            +K  +R
Sbjct: 159 AKKEKKR 165


>BC048959-1|AAH48959.1|  569|Homo sapiens ARID4B protein protein.
          Length = 569

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 508 EPKERSDENEPEQNQVLIKTESRTGYVNLDGTERENANESNLSDLV-KETINKYYNDTIN 566
           E K   DE E ++N +     S+   +    T  +   E N+      E ++   +DT  
Sbjct: 451 EEKPIEDEIERKEN-IKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTR 509

Query: 567 AETQENVKHSAEEPTA--GSSQTVEVDDIIVPEKSEVQLPSVTKTKEVMNMLPK 618
            +   N+K  AEE  A  G  + ++ D I+ P  ++  +P +   K++ N L K
Sbjct: 510 VDESLNIKVEAEEEKAKSGYDEWIKADKIVRP--ADKNVPKIKHRKKIKNKLDK 561


>BC041162-1|AAH41162.1|  722|Homo sapiens RNASEN protein protein.
          Length = 722

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)

Query: 617 PKVIQDFLNSDWKSKPKCEPQKMLERIRREQKYPDHPDVYKYELLLTPAPSFLQRISLAG 676
           P++ +  LN DW   PK + Q+    +R E K PD P    Y+ L T  PS  +  ++A 
Sbjct: 595 PRLKEFILNQDWND-PKSQLQQCCLTLRTEGKEPDIP---LYKTLQTVGPSHARTYTVAV 650

Query: 677 EFLNKK 682
            F  ++
Sbjct: 651 YFKGER 656


>AL391994-7|CAI13752.1| 1071|Homo sapiens AT rich interactive domain
           4B (RBP1-like) protein.
          Length = 1071

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 508 EPKERSDENEPEQNQVLIKTESRTGYVNLDGTERENANESNLSDLV-KETINKYYNDTIN 566
           E K   DE E ++N +     S+   +    T  +   E N+      E ++   +DT  
Sbjct: 451 EEKPIEDEIERKEN-IKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTR 509

Query: 567 AETQENVKHSAEEPTA--GSSQTVEVDDIIVPEKSEVQLPSVTKTKEVMNMLPK 618
            +   N+K  AEE  A  G  + ++ D I+ P  ++  +P +   K++ N L K
Sbjct: 510 VDESLNIKVEAEEEKAKSGYDEWIKADKIVRP--ADKNVPKIKHRKKIKNKLDK 561


>AL391994-6|CAI13751.1| 1226|Homo sapiens AT rich interactive domain
           4B (RBP1-like) protein.
          Length = 1226

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 508 EPKERSDENEPEQNQVLIKTESRTGYVNLDGTERENANESNLSDLV-KETINKYYNDTIN 566
           E K   DE E ++N +     S+   +    T  +   E N+      E ++   +DT  
Sbjct: 451 EEKPIEDEIERKEN-IKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTR 509

Query: 567 AETQENVKHSAEEPTA--GSSQTVEVDDIIVPEKSEVQLPSVTKTKEVMNMLPK 618
            +   N+K  AEE  A  G  + ++ D I+ P  ++  +P +   K++ N L K
Sbjct: 510 VDESLNIKVEAEEEKAKSGYDEWIKADKIVRP--ADKNVPKIKHRKKIKNKLDK 561


>AL133418-7|CAI22963.1| 1071|Homo sapiens AT rich interactive domain
           4B (RBP1-like) protein.
          Length = 1071

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 508 EPKERSDENEPEQNQVLIKTESRTGYVNLDGTERENANESNLSDLV-KETINKYYNDTIN 566
           E K   DE E ++N +     S+   +    T  +   E N+      E ++   +DT  
Sbjct: 451 EEKPIEDEIERKEN-IKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTR 509

Query: 567 AETQENVKHSAEEPTA--GSSQTVEVDDIIVPEKSEVQLPSVTKTKEVMNMLPK 618
            +   N+K  AEE  A  G  + ++ D I+ P  ++  +P +   K++ N L K
Sbjct: 510 VDESLNIKVEAEEEKAKSGYDEWIKADKIVRP--ADKNVPKIKHRKKIKNKLDK 561


>AL133418-6|CAI22962.1| 1226|Homo sapiens AT rich interactive domain
           4B (RBP1-like) protein.
          Length = 1226

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 508 EPKERSDENEPEQNQVLIKTESRTGYVNLDGTERENANESNLSDLV-KETINKYYNDTIN 566
           E K   DE E ++N +     S+   +    T  +   E N+      E ++   +DT  
Sbjct: 451 EEKPIEDEIERKEN-IKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTR 509

Query: 567 AETQENVKHSAEEPTA--GSSQTVEVDDIIVPEKSEVQLPSVTKTKEVMNMLPK 618
            +   N+K  AEE  A  G  + ++ D I+ P  ++  +P +   K++ N L K
Sbjct: 510 VDESLNIKVEAEEEKAKSGYDEWIKADKIVRP--ADKNVPKIKHRKKIKNKLDK 561


>AK001121-1|BAA91511.1|  769|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10259 fis, clone HEMBB1000947, highly similar to
           Homo sapiens clone HAW100 putative ribonuclease III
           mRNA. ).
          Length = 769

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)

Query: 617 PKVIQDFLNSDWKSKPKCEPQKMLERIRREQKYPDHPDVYKYELLLTPAPSFLQRISLAG 676
           P++ +  LN DW   PK + Q+    +R E K PD P    Y+ L T  PS  +  ++A 
Sbjct: 642 PRLKEFILNQDWND-PKSQLQQCCLTLRTEGKEPDIP---LYKTLQTVGPSHARTYTVAV 697

Query: 677 EFLNKK 682
            F  ++
Sbjct: 698 YFKGER 703


>AF214114-1|AAF28341.2| 1226|Homo sapiens retinoblastoma-binding
           protein 1-like 1 protein.
          Length = 1226

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 508 EPKERSDENEPEQNQVLIKTESRTGYVNLDGTERENANESNLSDLV-KETINKYYNDTIN 566
           E K   DE E ++N +     S+   +    T  +   E N+      E ++   +DT  
Sbjct: 451 EEKPIEDEIERKEN-IKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTR 509

Query: 567 AETQENVKHSAEEPTA--GSSQTVEVDDIIVPEKSEVQLPSVTKTKEVMNMLPK 618
            +   N+K  AEE  A  G  + ++ D I+ P  ++  +P +   K++ N L K
Sbjct: 510 VDESLNIKVEAEEEKAKSGYDEWIKADKIVRP--ADKNVPKIKHRKKIKNKLDK 561


>AF208045-1|AAF23433.3| 1213|Homo sapiens breast cancer-associated
           antigen BRCAA1 protein.
          Length = 1213

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 6/114 (5%)

Query: 508 EPKERSDENEPEQNQVLIKTESRTGYVNLDGTERENANESNLSDLV-KETINKYYNDTIN 566
           E K   DE E ++N +     S+   +    T  +   E N+      E ++   +DT  
Sbjct: 456 EEKPIEDEIERKEN-IKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTR 514

Query: 567 AETQENVKHSAEEPTA--GSSQTVEVDDIIVPEKSEVQLPSVTKTKEVMNMLPK 618
            +   N+K  AEE  A  G  + ++ D I+ P  ++  +P +   K++ N L K
Sbjct: 515 VDESLNIKVEAEEEKAKSGYDEWIKADKIVRP--ADKNVPKIKHRKKIKNKLDK 566


>AF189011-1|AAF80558.1| 1374|Homo sapiens ribonuclease III protein.
          Length = 1374

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)

Query: 617  PKVIQDFLNSDWKSKPKCEPQKMLERIRREQKYPDHPDVYKYELLLTPAPSFLQRISLAG 676
            P++ +  LN DW   PK + Q+    +R E K PD P    Y+ L T  PS  +  ++A 
Sbjct: 1247 PRLKEFILNQDWND-PKSQLQQCCLTLRTEGKEPDIP---LYKTLQTVGPSHARTYTVAV 1302

Query: 677  EFLNKK 682
             F  ++
Sbjct: 1303 YFKGER 1308


>AF116910-1|AAD29637.1|  541|Homo sapiens putative ribonuclease III
           protein.
          Length = 541

 Score = 33.1 bits (72), Expect = 3.4
 Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 4/66 (6%)

Query: 617 PKVIQDFLNSDWKSKPKCEPQKMLERIRREQKYPDHPDVYKYELLLTPAPSFLQRISLAG 676
           P++ +  LN DW   PK + Q+    +R E K PD P    Y+ L T  PS  +  ++A 
Sbjct: 414 PRLKEFILNQDWND-PKSQLQQCCLTLRTEGKEPDIP---LYKTLQTVGPSHARTYTVAV 469

Query: 677 EFLNKK 682
            F  ++
Sbjct: 470 YFKGER 475


>AL137350-1|CAB70705.1|  438|Homo sapiens hypothetical protein
           protein.
          Length = 438

 Score = 32.7 bits (71), Expect = 4.4
 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 513 SDENEPEQNQVLIKTESRTGYVNLDGTERENANESNLSDLVK-ETINKYYNDTINAETQE 571
           S E+EP+ N  ++ +   T       TE  +  E N  DL +    +   N T +   +E
Sbjct: 336 SSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEE 395

Query: 572 NVKHSAEEPTAGSSQTVEVDDIIVPEKSEVQLPSVTKTKE 611
             ++S+ E T G       DD I  +  E   P + K K+
Sbjct: 396 KDEYSSSE-TTGEKPEQNDDDTI--KSQEEDQPIIIKRKK 432


>BC112357-1|AAI12358.1|  488|Homo sapiens C9orf84 protein protein.
          Length = 488

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 1/38 (2%)

Query: 584 SSQTVEVDDIIVPE-KSEVQLPSVTKTKEVMNMLPKVI 620
           SS  +E + +I P  K E+ +PS+++ KE++N +P++I
Sbjct: 238 SSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEII 275


>BC041858-1|AAH41858.1|  356|Homo sapiens C9orf84 protein protein.
          Length = 356

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 1/38 (2%)

Query: 584 SSQTVEVDDIIVPE-KSEVQLPSVTKTKEVMNMLPKVI 620
           SS  +E + +I P  K E+ +PS+++ KE++N +P++I
Sbjct: 120 SSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEII 157


>BC016987-1|AAH16987.1|  284|Homo sapiens FAM44A protein protein.
          Length = 284

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 4/99 (4%)

Query: 513 SDENEPEQNQVLIKTESRTGYVNLDGTERENANESNLSDLVK-ETINKYYNDTINAETQE 571
           S E+EP+ N  ++ +   T       TE  +  E N  DL +    +   N T +   +E
Sbjct: 12  SSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEE 71

Query: 572 NVKHSAEEPTAGSSQTVEVDDIIVPEKSEVQLPSVTKTK 610
             ++S+ E T G       DD I  +  E   P + K K
Sbjct: 72  KDEYSSSE-TTGEKPEQNDDDTI--KSQEEDQPIIIKRK 107


>AL356491-3|CAM16657.1| 1405|Homo sapiens chromosome 9 open reading
           frame 84 protein.
          Length = 1405

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 1/38 (2%)

Query: 584 SSQTVEVDDIIVPE-KSEVQLPSVTKTKEVMNMLPKVI 620
           SS  +E + +I P  K E+ +PS+++ KE++N +P++I
Sbjct: 135 SSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEII 172


>AL356491-2|CAH72339.1|  488|Homo sapiens chromosome 9 open reading
           frame 84 protein.
          Length = 488

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 1/38 (2%)

Query: 584 SSQTVEVDDIIVPE-KSEVQLPSVTKTKEVMNMLPKVI 620
           SS  +E + +I P  K E+ +PS+++ KE++N +P++I
Sbjct: 238 SSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEII 275


>AL356491-1|CAH72338.1| 1444|Homo sapiens chromosome 9 open reading
           frame 84 protein.
          Length = 1444

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 1/38 (2%)

Query: 584 SSQTVEVDDIIVPE-KSEVQLPSVTKTKEVMNMLPKVI 620
           SS  +E + +I P  K E+ +PS+++ KE++N +P++I
Sbjct: 174 SSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEII 211


>AL354877-2|CAH73770.1|  488|Homo sapiens chromosome 9 open reading
           frame 84 protein.
          Length = 488

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 1/38 (2%)

Query: 584 SSQTVEVDDIIVPE-KSEVQLPSVTKTKEVMNMLPKVI 620
           SS  +E + +I P  K E+ +PS+++ KE++N +P++I
Sbjct: 238 SSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEII 275


>AL354877-1|CAH73769.1| 1444|Homo sapiens chromosome 9 open reading
           frame 84 protein.
          Length = 1444

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 1/38 (2%)

Query: 584 SSQTVEVDDIIVPE-KSEVQLPSVTKTKEVMNMLPKVI 620
           SS  +E + +I P  K E+ +PS+++ KE++N +P++I
Sbjct: 174 SSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEII 211


>AL135787-6|CAM13383.1| 1405|Homo sapiens chromosome 9 open reading
           frame 84 protein.
          Length = 1405

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 1/38 (2%)

Query: 584 SSQTVEVDDIIVPE-KSEVQLPSVTKTKEVMNMLPKVI 620
           SS  +E + +I P  K E+ +PS+++ KE++N +P++I
Sbjct: 135 SSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEII 172


>AL135787-1|CAI12399.1| 1444|Homo sapiens chromosome 9 open reading
           frame 84 protein.
          Length = 1444

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 1/38 (2%)

Query: 584 SSQTVEVDDIIVPE-KSEVQLPSVTKTKEVMNMLPKVI 620
           SS  +E + +I P  K E+ +PS+++ KE++N +P++I
Sbjct: 174 SSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEII 211


>AK057341-1|BAB71436.1|  488|Homo sapiens protein ( Homo sapiens
           cDNA FLJ32779 fis, clone TESTI2002090. ).
          Length = 488

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 14/38 (36%), Positives = 27/38 (71%), Gaps = 1/38 (2%)

Query: 584 SSQTVEVDDIIVPE-KSEVQLPSVTKTKEVMNMLPKVI 620
           SS  +E + +I P  K E+ +PS+++ KE++N +P++I
Sbjct: 238 SSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEII 275


>AB037748-1|BAA92565.2| 1804|Homo sapiens KIAA1327 protein protein.
          Length = 1804

 Score = 32.3 bits (70), Expect = 5.9
 Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 4/99 (4%)

Query: 513  SDENEPEQNQVLIKTESRTGYVNLDGTERENANESNLSDLVK-ETINKYYNDTINAETQE 571
            S E+EP+ N  ++ +   T       TE  +  E N  DL +    +   N T +   +E
Sbjct: 1532 SSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEE 1591

Query: 572  NVKHSAEEPTAGSSQTVEVDDIIVPEKSEVQLPSVTKTK 610
              ++S+ E T G       DD I  +  E   P + K K
Sbjct: 1592 KDEYSSSE-TTGEKPEQNDDDTI--KSQEEDQPIIIKRK 1627


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.317    0.136    0.404 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,350,443
Number of Sequences: 224733
Number of extensions: 4260199
Number of successful extensions: 15847
Number of sequences better than 10.0: 71
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 15604
Number of HSP's gapped (non-prelim): 123
length of query: 686
length of database: 73,234,838
effective HSP length: 95
effective length of query: 591
effective length of database: 51,885,203
effective search space: 30664154973
effective search space used: 30664154973
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 69 (31.9 bits)

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