BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001004-TA|BGIBMGA001004-PA|IPR001128|Cytochrome P450, IPR000923|Blue (type 1) copper domain, IPR002401|E-class P450, group I (507 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9VYY4 Cluster: Cytochrome P450 4g15; n=8; Neoptera|Rep... 605 e-171 UniRef50_Q9V3S0 Cluster: Cytochrome P450 4g1; n=62; Protostomia|... 515 e-145 UniRef50_Q967Y5 Cluster: Cytochrome P450 CYP4G13v2; n=4; Neopter... 496 e-139 UniRef50_A0A8M5 Cluster: Cytochrome P450 4 family; n=1; Daphnia ... 363 4e-99 UniRef50_Q9VA27 Cluster: Cytochrome P450 4c3; n=15; Coelomata|Re... 363 8e-99 UniRef50_Q170T4 Cluster: Cytochrome P450; n=5; Endopterygota|Rep... 318 2e-85 UniRef50_Q27589 Cluster: Cytochrome P450 4d2; n=8; Acalyptratae|... 299 1e-79 UniRef50_UPI00015B569E Cluster: PREDICTED: similar to cytochrome... 299 1e-79 UniRef50_UPI00015B5D09 Cluster: PREDICTED: similar to cytochrome... 297 3e-79 UniRef50_Q6VAB7 Cluster: Cytochrome P450 CYP4AB2; n=6; Apocrita|... 297 3e-79 UniRef50_A0MNW4 Cluster: Cyp4M9; n=20; Obtectomera|Rep: Cyp4M9 -... 288 3e-76 UniRef50_Q9VS79 Cluster: Cytochrome P450 4d8; n=6; Schizophora|R... 278 2e-73 UniRef50_Q170T0 Cluster: Cytochrome P450; n=12; Culicidae|Rep: C... 277 5e-73 UniRef50_UPI0000D55ACE Cluster: PREDICTED: similar to Cytochrome... 275 2e-72 UniRef50_UPI00015B604A Cluster: PREDICTED: similar to cytochrome... 272 2e-71 UniRef50_A7SWY9 Cluster: Predicted protein; n=3; Nematostella ve... 272 2e-71 UniRef50_Q9Y1T8 Cluster: Cytochrome P450 4W1; n=3; Arthropoda|Re... 256 1e-66 UniRef50_Q9NB96 Cluster: P450 CYP319A1; n=2; Parasitiformes|Rep:... 255 2e-66 UniRef50_Q9N574 Cluster: Cytochrome p450 family protein 31A3; n=... 254 5e-66 UniRef50_UPI00015B4DC8 Cluster: PREDICTED: similar to corpora al... 248 3e-64 UniRef50_Q4R1I7 Cluster: Cytochrome P450; n=1; Papilio xuthus|Re... 239 2e-61 UniRef50_O45120 Cluster: Family 4 cytochrome P450; n=2; Coptoter... 237 4e-61 UniRef50_Q170S9 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cy... 234 5e-60 UniRef50_Q16ML8 Cluster: Cytochrome P450; n=3; Culicidae|Rep: Cy... 232 1e-59 UniRef50_UPI00015B5014 Cluster: PREDICTED: similar to cytochrome... 229 1e-58 UniRef50_UPI00015B561A Cluster: PREDICTED: similar to cytochrome... 221 3e-56 UniRef50_A0JMQ6 Cluster: Cytochrome P450, family 4, subfamily V,... 215 2e-54 UniRef50_Q6ZWL3 Cluster: Cytochrome P450 4V2; n=83; Coelomata|Re... 214 5e-54 UniRef50_UPI0000D566B3 Cluster: PREDICTED: similar to Cytochrome... 212 2e-53 UniRef50_UPI00015B569D Cluster: PREDICTED: similar to cytochrome... 210 7e-53 UniRef50_Q964T1 Cluster: Cytochrome P450 4c21; n=1; Blattella ge... 203 1e-50 UniRef50_Q7YSZ3 Cluster: P450 enzyme precursor; n=1; Rhodnius pr... 202 2e-50 UniRef50_Q9VVN6 Cluster: Probable cytochrome P450 312a1; n=2; So... 202 2e-50 UniRef50_UPI0000E46807 Cluster: PREDICTED: similar to cytochrome... 201 3e-50 UniRef50_Q9NGQ5 Cluster: Insecticide resistance-associated cytoc... 196 1e-48 UniRef50_A6Y7S1 Cluster: Female neotenic-specific protein 4; n=1... 196 2e-48 UniRef50_Q695H3 Cluster: Pheromone-degrading enzyme; n=2; Phyllo... 195 2e-48 UniRef50_O76478 Cluster: Corpora allata cytochrome P450; n=2; Ne... 195 2e-48 UniRef50_A1BPS2 Cluster: CYP4BF1; n=2; Ips paraconfusus|Rep: CYP... 195 3e-48 UniRef50_UPI0000E46144 Cluster: PREDICTED: similar to ENSANGP000... 192 2e-47 UniRef50_Q27472 Cluster: Cytochrome p450 family protein 32A1; n=... 192 2e-47 UniRef50_UPI0000D55952 Cluster: PREDICTED: similar to Cytochrome... 191 4e-47 UniRef50_UPI00015B560A Cluster: PREDICTED: similar to cytochrome... 188 3e-46 UniRef50_UPI0000D56049 Cluster: PREDICTED: similar to Probable c... 188 3e-46 UniRef50_Q178T9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep... 188 4e-46 UniRef50_Q9U1R5 Cluster: Putative uncharacterized protein cyp-42... 186 1e-45 UniRef50_Q7YXL0 Cluster: Cytochrome P450 monooxygenase; n=2; Tri... 183 1e-44 UniRef50_Q8ISJ7 Cluster: Cytochrome P450 CYP4L4; n=4; Noctuidae|... 182 3e-44 UniRef50_UPI00015B61D7 Cluster: PREDICTED: similar to Cytochrome... 181 5e-44 UniRef50_UPI0000D56462 Cluster: PREDICTED: similar to cytochrome... 180 6e-44 UniRef50_Q8ISJ8 Cluster: Cytochrome P450 CYP4S4; n=3; Noctuidae|... 180 8e-44 UniRef50_O17851 Cluster: Putative uncharacterized protein cyp-37... 178 3e-43 UniRef50_A1BPS5 Cluster: CYP4BJ1; n=1; Ips paraconfusus|Rep: CYP... 178 3e-43 UniRef50_Q9N4Q5 Cluster: Cytochrome p450 family protein 32B1; n=... 176 1e-42 UniRef50_Q9VXY0 Cluster: Probable cytochrome P450 4s3; n=5; Acal... 175 2e-42 UniRef50_A1BPS4 Cluster: CYP4BH1; n=1; Ips paraconfusus|Rep: CYP... 174 4e-42 UniRef50_UPI0000D55B03 Cluster: PREDICTED: similar to Cytochrome... 173 7e-42 UniRef50_Q9VMS9 Cluster: Probable cytochrome P450 4ac1; n=5; Sop... 169 1e-40 UniRef50_Q16IS6 Cluster: Cytochrome P450; n=12; Culicidae|Rep: C... 167 8e-40 UniRef50_UPI00015B5E04 Cluster: PREDICTED: similar to CG8302-PA;... 166 1e-39 UniRef50_Q16I47 Cluster: Cytochrome P450; n=7; Culicidae|Rep: Cy... 166 1e-39 UniRef50_Q170T3 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 165 2e-39 UniRef50_Q17PE3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep... 164 6e-39 UniRef50_Q16P39 Cluster: Cytochrome P450; n=7; Aedes aegypti|Rep... 164 6e-39 UniRef50_Q9V7G5 Cluster: Probable cytochrome P450 4aa1; n=5; Dip... 164 6e-39 UniRef50_Q9XVA6 Cluster: Putative uncharacterized protein cyp-37... 163 1e-38 UniRef50_Q9V558 Cluster: Cytochrome P450 4p1; n=5; Sophophora|Re... 163 1e-38 UniRef50_Q9N525 Cluster: Cytochrome p450 family protein 29A3; n=... 163 1e-38 UniRef50_Q16E69 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 162 2e-38 UniRef50_A1BPR9 Cluster: CYP4BD1; n=1; Ips paraconfusus|Rep: CYP... 160 9e-38 UniRef50_UPI0000D5646A Cluster: PREDICTED: similar to CYtochrome... 159 1e-37 UniRef50_Q27606 Cluster: Cytochrome P450 4e2; n=11; Diptera|Rep:... 157 5e-37 UniRef50_A1BPS3 Cluster: CYP4BG1; n=1; Ips paraconfusus|Rep: CYP... 157 9e-37 UniRef50_P33269 Cluster: Cytochrome P450 4d1; n=11; Diptera|Rep:... 157 9e-37 UniRef50_O46054 Cluster: Cytochrome P450 4ae1; n=1; Drosophila m... 157 9e-37 UniRef50_Q9VLZ7 Cluster: Probable cytochrome P450 4d21; n=5; Sop... 156 1e-36 UniRef50_UPI00015B5723 Cluster: PREDICTED: similar to cytochrome... 155 2e-36 UniRef50_Q16L55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 155 3e-36 UniRef50_P13584 Cluster: Cytochrome P450 4B1; n=32; Euteleostomi... 155 3e-36 UniRef50_UPI00015B5196 Cluster: PREDICTED: similar to cytochrome... 154 6e-36 UniRef50_Q179B7 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 154 6e-36 UniRef50_UPI0000F2BA18 Cluster: PREDICTED: similar to Cytochrome... 153 1e-35 UniRef50_UPI0000D9991B Cluster: PREDICTED: similar to cytochrome... 152 2e-35 UniRef50_UPI0000D56470 Cluster: PREDICTED: similar to Cytochrome... 150 7e-35 UniRef50_Q6TGT4 Cluster: Thromboxane A synthase 1; n=6; cellular... 148 3e-34 UniRef50_Q6PW73 Cluster: Cytochrome P450 CYP4AT1; n=1; Capitella... 147 5e-34 UniRef50_Q02928 Cluster: Cytochrome P450 4A11 precursor; n=114; ... 146 9e-34 UniRef50_Q9VG40 Cluster: Probable cytochrome P450 313a4; n=3; So... 145 2e-33 UniRef50_Q4U3Y4 Cluster: CYP325C2; n=4; Anopheles gambiae|Rep: C... 144 4e-33 UniRef50_Q16L50 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 144 4e-33 UniRef50_Q8N118 Cluster: Cytochrome P450 4X1; n=12; Mammalia|Rep... 144 4e-33 UniRef50_Q6NT55 Cluster: Cytochrome P450 4F22; n=127; Deuterosto... 144 5e-33 UniRef50_Q6SPQ6 Cluster: CYP4BB1; n=2; Protostomia|Rep: CYP4BB1 ... 144 6e-33 UniRef50_Q8K4D6 Cluster: Cytochrome P450 4X1; n=15; Eutheria|Rep... 143 8e-33 UniRef50_Q5XM61 Cluster: Cytochrome P450; n=9; Pancrustacea|Rep:... 142 1e-32 UniRef50_Q5V5P9 Cluster: Cytochrome P450; n=3; Halobacteriaceae|... 142 1e-32 UniRef50_Q8WQN5 Cluster: Cytochrome P450 CYP4H14; n=22; Endopter... 142 3e-32 UniRef50_Q176V3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep... 141 5e-32 UniRef50_UPI0000D56469 Cluster: PREDICTED: similar to cytochrome... 140 6e-32 UniRef50_A6GGL1 Cluster: Cytochrome P450 family protein; n=1; Pl... 140 8e-32 UniRef50_Q17DZ0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 140 1e-31 UniRef50_A1BPR7 Cluster: CYP4AY1; n=2; Ips paraconfusus|Rep: CYP... 139 1e-31 UniRef50_Q9KFA6 Cluster: Cytochrome P450 hydroxylase; n=1; Bacil... 139 2e-31 UniRef50_UPI0001555B83 Cluster: PREDICTED: similar to cytochrome... 138 2e-31 UniRef50_UPI0000D56468 Cluster: PREDICTED: similar to Cytochrome... 138 2e-31 UniRef50_Q3IR83 Cluster: Unspecific monooxygenase; n=1; Natronom... 138 3e-31 UniRef50_Q82D73 Cluster: Putative cytochrome P450; n=2; Streptom... 136 1e-30 UniRef50_UPI0000D55FA3 Cluster: PREDICTED: similar to Cytochrome... 136 2e-30 UniRef50_Q6SPQ5 Cluster: CYP342A1; n=1; Nereis virens|Rep: CYP34... 136 2e-30 UniRef50_Q4U3Y5 Cluster: CYP325D1; n=1; Anopheles gambiae|Rep: C... 134 7e-30 UniRef50_Q4STK8 Cluster: Chromosome undetermined SCAF14158, whol... 133 9e-30 UniRef50_A7SJV6 Cluster: Predicted protein; n=3; Nematostella ve... 133 9e-30 UniRef50_Q98T91 Cluster: Cytochrome P450 3A40; n=16; Euteleostom... 133 1e-29 UniRef50_Q6PH32 Cluster: Cytochrome P450, family 4; n=7; Clupeoc... 132 2e-29 UniRef50_Q3L917 Cluster: Cytochrome P450; n=1; Rhodococcus eryth... 132 2e-29 UniRef50_P05184 Cluster: Cytochrome P450 3A3; n=159; Euteleostom... 132 3e-29 UniRef50_A7D7T8 Cluster: Cytochrome P450; n=1; Halorubrum lacusp... 131 5e-29 UniRef50_Q8WQN9 Cluster: Cytochrome P450 CYP4J5; n=22; Endoptery... 130 6e-29 UniRef50_Q095M8 Cluster: Cytochrome P450 4A5; n=1; Stigmatella a... 130 8e-29 UniRef50_A7DM29 Cluster: Cytochrome P450; n=2; Methylobacterium ... 130 1e-28 UniRef50_Q3I414 Cluster: Cytochrome P450; n=18; Cucujiformia|Rep... 129 1e-28 UniRef50_Q177R7 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep... 128 5e-28 UniRef50_Q495Y1 Cluster: CYP3A43 protein; n=4; Homo sapiens|Rep:... 128 5e-28 UniRef50_Q8WQN1 Cluster: Cytochrome P450 CYP4H24; n=23; Culicida... 127 6e-28 UniRef50_Q8T632 Cluster: Cytochrome P450 CYP6P3; n=42; Diptera|R... 127 6e-28 UniRef50_Q16TD6 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep... 126 1e-27 UniRef50_UPI0000D56467 Cluster: PREDICTED: similar to Cytochrome... 126 1e-27 UniRef50_Q06GC7 Cluster: Cytochrome P450; n=1; Rhodococcus sp. N... 126 1e-27 UniRef50_UPI000038CC01 Cluster: COG2124: Cytochrome P450; n=1; N... 126 2e-27 UniRef50_Q964R1 Cluster: Cytochrome P450 6j1; n=1; Blattella ger... 126 2e-27 UniRef50_Q0IG08 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 125 2e-27 UniRef50_UPI00015B4AC4 Cluster: PREDICTED: similar to cytochrome... 124 4e-27 UniRef50_A3RK60 Cluster: Cytochrome P450; n=2; Liposcelis bostry... 124 6e-27 UniRef50_Q9PVE8 Cluster: Cytochrome P450 3A30; n=4; Percomorpha|... 124 6e-27 UniRef50_Q9VGB3 Cluster: Probable cytochrome P450 313a3; n=2; Dr... 124 7e-27 UniRef50_Q3E385 Cluster: Cytochrome P450; n=3; Chloroflexus|Rep:... 123 1e-26 UniRef50_Q17PE0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 123 1e-26 UniRef50_A7RNE6 Cluster: Predicted protein; n=1; Nematostella ve... 123 1e-26 UniRef50_UPI0000D555E9 Cluster: PREDICTED: similar to Cytochrome... 123 1e-26 UniRef50_Q5KR92 Cluster: Cytochrome P450; n=1; Hodotermopsis sjo... 123 1e-26 UniRef50_UPI00015B480C Cluster: PREDICTED: similar to cytochrome... 122 2e-26 UniRef50_UPI0000D5558E Cluster: PREDICTED: similar to Cytochrome... 122 2e-26 UniRef50_Q964R0 Cluster: Cytochrome P450 6k1; n=1; Blattella ger... 122 2e-26 UniRef50_UPI0000DB7C31 Cluster: PREDICTED: similar to Probable c... 122 2e-26 UniRef50_Q629N7 Cluster: Cytochrome P450-related protein; n=24; ... 122 2e-26 UniRef50_Q27691 Cluster: Cytochrome P450; n=2; Musca domestica|R... 122 2e-26 UniRef50_A7SRX7 Cluster: Predicted protein; n=2; Nematostella ve... 122 2e-26 UniRef50_Q5TXA2 Cluster: ENSANGP00000026709; n=2; Anopheles gamb... 122 3e-26 UniRef50_A7SCY4 Cluster: Predicted protein; n=1; Nematostella ve... 122 3e-26 UniRef50_Q70AR5 Cluster: Putative cytochrome P450; n=1; Streptom... 121 4e-26 UniRef50_Q1D9Z9 Cluster: Cytochrome P450 family protein; n=1; My... 121 4e-26 UniRef50_Q25176 Cluster: Cytochrome P-450; n=24; Ditrysia|Rep: C... 121 4e-26 UniRef50_A7HP72 Cluster: Cytochrome P450; n=1; Parvibaculum lava... 121 5e-26 UniRef50_UPI0000E48D2E Cluster: PREDICTED: similar to MGC64404 p... 120 7e-26 UniRef50_Q1IM54 Cluster: Cytochrome P450; n=1; Acidobacteria bac... 120 7e-26 UniRef50_A5P357 Cluster: Cytochrome P450; n=1; Methylobacterium ... 120 7e-26 UniRef50_Q964T2 Cluster: Cytochrome P450 9e2; n=2; Blattaria|Rep... 120 7e-26 UniRef50_UPI0000E4657A Cluster: PREDICTED: similar to cytochrome... 120 9e-26 UniRef50_O76345 Cluster: Cytochrome P450; n=1; Homarus americanu... 120 9e-26 UniRef50_UPI00015B5073 Cluster: PREDICTED: similar to cytochrome... 120 1e-25 UniRef50_Q9VYQ7 Cluster: Probable cytochrome P450 311a1; n=2; Dr... 120 1e-25 UniRef50_UPI0000D576F7 Cluster: PREDICTED: similar to Cytochrome... 119 2e-25 UniRef50_Q825N1 Cluster: Cytochrome P450 hydroxylase; n=6; Actin... 119 2e-25 UniRef50_A4X8D8 Cluster: Cytochrome P450; n=5; Actinomycetales|R... 119 2e-25 UniRef50_A1UDQ6 Cluster: Cytochrome P450; n=10; Mycobacterium|Re... 119 2e-25 UniRef50_Q8UF31 Cluster: Cytochrome P450; n=1; Agrobacterium tum... 119 2e-25 UniRef50_Q89R90 Cluster: Blr2882 protein; n=4; Bacteria|Rep: Blr... 119 2e-25 UniRef50_UPI0000D56428 Cluster: PREDICTED: similar to Cytochrome... 118 3e-25 UniRef50_O76107 Cluster: Cytochrome P450; n=2; Culicini|Rep: Cyt... 118 3e-25 UniRef50_A7SXR0 Cluster: Predicted protein; n=5; Nematostella ve... 118 3e-25 UniRef50_UPI0000F21E21 Cluster: PREDICTED: similar to cytochrome... 118 4e-25 UniRef50_Q1DEH2 Cluster: Cytochrome P450 family protein; n=1; My... 118 4e-25 UniRef50_Q9V4T3 Cluster: Probable cytochrome P450 4ad1; n=2; Sop... 118 4e-25 UniRef50_Q9PWP0 Cluster: Cytochrome P450; n=2; Dicentrarchus lab... 118 5e-25 UniRef50_A1WAC7 Cluster: Cytochrome P450; n=1; Acidovorax sp. JS... 118 5e-25 UniRef50_A7LFI0 Cluster: Cytochrome P450; n=3; Tribolium castane... 118 5e-25 UniRef50_A0NGH0 Cluster: ENSANGP00000031109; n=7; Culicidae|Rep:... 118 5e-25 UniRef50_UPI000065CBAF Cluster: Thromboxane-A synthase (EC 5.3.9... 117 6e-25 UniRef50_UPI00015B5352 Cluster: PREDICTED: similar to cytochrome... 117 8e-25 UniRef50_A7DLL5 Cluster: Cytochrome P450; n=1; Methylobacterium ... 117 8e-25 UniRef50_UPI00005A2E9B Cluster: PREDICTED: similar to cytochrome... 116 1e-24 UniRef50_Q0LLJ2 Cluster: Cytochrome P450; n=1; Herpetosiphon aur... 116 1e-24 UniRef50_Q5W1K7 Cluster: Cytochrome P450 CYP6AY1 protein; n=3; H... 116 1e-24 UniRef50_Q309A5 Cluster: Cytochrome P450 monooxygenase; n=22; Ap... 116 1e-24 UniRef50_Q27594 Cluster: Cytochrome P450 6a9; n=15; Schizophora|... 116 1e-24 UniRef50_Q8T624 Cluster: Cytochrome P450 CYP9L1 protein; n=6; Ce... 116 1e-24 UniRef50_Q0IEL1 Cluster: Cytochrome P450; n=6; Culicini|Rep: Cyt... 116 1e-24 UniRef50_O16156 Cluster: Cytochrome P450 30; n=1; Mercenaria mer... 116 1e-24 UniRef50_Q9VGB4 Cluster: Probable cytochrome P450 313a2; n=2; Dr... 116 1e-24 UniRef50_Q5U3Q3 Cluster: Cytochrome P450, family 3, subfamily c,... 116 2e-24 UniRef50_Q56JT9 Cluster: Cytochrome P450 monooxygenase; n=10; En... 116 2e-24 UniRef50_UPI0000D56564 Cluster: PREDICTED: similar to Probable c... 115 3e-24 UniRef50_A7RQ80 Cluster: Predicted protein; n=5; Nematostella ve... 115 3e-24 UniRef50_UPI0000D56E82 Cluster: PREDICTED: similar to Cytochrome... 114 4e-24 UniRef50_Q178V0 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cy... 114 4e-24 UniRef50_A7RSL1 Cluster: Predicted protein; n=2; Nematostella ve... 114 4e-24 UniRef50_Q8WQM9 Cluster: Cytochrome P450 CYP6M1; n=7; Culicidae|... 114 6e-24 UniRef50_Q8MZK0 Cluster: Cytochrome P450; n=6; Culicidae|Rep: Cy... 114 6e-24 UniRef50_Q695H1 Cluster: Antennae-rich cytochrome P450; n=3; Pol... 114 6e-24 UniRef50_UPI00015B4FBC Cluster: PREDICTED: similar to cytochrome... 113 8e-24 UniRef50_A0NQ01 Cluster: Cytochrome P450; n=1; Stappia aggregata... 113 8e-24 UniRef50_Q9GQM9 Cluster: Cytochrome P450 6l1; n=1; Blattella ger... 113 8e-24 UniRef50_Q9VGB5 Cluster: Probable cytochrome P450 313a5; n=2; Dr... 113 8e-24 UniRef50_Q0LL77 Cluster: Cytochrome P450; n=1; Herpetosiphon aur... 113 1e-23 UniRef50_Q8MTC8 Cluster: Cytochrome P450 monooxygenase CYP321A1;... 113 1e-23 UniRef50_UPI0000D576F6 Cluster: PREDICTED: similar to Probable c... 113 1e-23 UniRef50_A1ZWE3 Cluster: Cytochrome P450 family protein; n=1; Mi... 113 1e-23 UniRef50_Q9BID0 Cluster: Cytochrome P450; n=27; Culicidae|Rep: C... 113 1e-23 UniRef50_P33270 Cluster: Cytochrome P450 6a2; n=10; Diptera|Rep:... 113 1e-23 UniRef50_UPI0000E473EA Cluster: PREDICTED: hypothetical protein;... 112 2e-23 UniRef50_Q70AR8 Cluster: Putative cytochrome P450; n=1; Streptom... 112 2e-23 UniRef50_UPI0000DB7562 Cluster: PREDICTED: similar to Probable c... 111 3e-23 UniRef50_Q0LHR9 Cluster: Cytochrome P450; n=1; Herpetosiphon aur... 111 4e-23 UniRef50_A7RMN2 Cluster: Predicted protein; n=1; Nematostella ve... 111 4e-23 UniRef50_UPI0000D577ED Cluster: PREDICTED: similar to Cytochrome... 111 6e-23 UniRef50_Q0LFI0 Cluster: Cytochrome P450; n=1; Herpetosiphon aur... 111 6e-23 UniRef50_A5FJE6 Cluster: Cytochrome P450; n=1; Flavobacterium jo... 111 6e-23 UniRef50_Q6PW74 Cluster: Cytochrome P450 CYP331A1; n=1; Capitell... 110 7e-23 UniRef50_UPI0000D5650B Cluster: PREDICTED: similar to Cytochrome... 110 1e-22 UniRef50_A2XB72 Cluster: Putative uncharacterized protein; n=2; ... 109 1e-22 UniRef50_Q234S0 Cluster: Cytochrome P450 family protein; n=2; Te... 109 1e-22 UniRef50_Q179B9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep... 109 1e-22 UniRef50_Q0UKV8 Cluster: Putative uncharacterized protein; n=1; ... 109 1e-22 UniRef50_A1DAX0 Cluster: Cytochrome P450; n=5; Trichocomaceae|Re... 109 1e-22 UniRef50_Q70AR1 Cluster: Putative cytochrome P450; n=1; Streptom... 109 2e-22 UniRef50_Q7QCC3 Cluster: ENSANGP00000012179; n=1; Anopheles gamb... 109 2e-22 UniRef50_Q93VK5 Cluster: At1g31800/68069_m00159; n=12; Magnoliop... 109 2e-22 UniRef50_Q2Y711 Cluster: Cytochrome P450; n=1; Nitrosospira mult... 107 5e-22 UniRef50_Q9NB69 Cluster: Cytochrome P450 monooxygenase; n=2; Tri... 107 5e-22 UniRef50_A6WEH8 Cluster: Cytochrome P450; n=1; Kineococcus radio... 107 7e-22 UniRef50_A7T1A2 Cluster: Predicted protein; n=2; Nematostella ve... 107 7e-22 UniRef50_UPI0000E48EAF Cluster: PREDICTED: similar to cytochrome... 107 9e-22 UniRef50_UPI0000D5745C Cluster: PREDICTED: similar to Probable c... 107 9e-22 UniRef50_Q3EBT7 Cluster: Uncharacterized protein At2g26170.1; n=... 107 9e-22 UniRef50_Q29AT3 Cluster: GA11819-PA; n=6; Diptera|Rep: GA11819-P... 107 9e-22 UniRef50_Q9VG82 Cluster: Probable cytochrome P450 9f2; n=26; End... 107 9e-22 UniRef50_Q27664 Cluster: Cytochrome P450 6B2; n=46; Obtectomera|... 107 9e-22 UniRef50_UPI00015B60B4 Cluster: PREDICTED: similar to cytochrome... 106 1e-21 UniRef50_UPI0000E473D8 Cluster: PREDICTED: hypothetical protein;... 106 1e-21 UniRef50_UPI0000E46433 Cluster: PREDICTED: similar to Cytochrome... 106 1e-21 UniRef50_Q82QD5 Cluster: Putative cytochrome P450 / NADPH-ferrih... 106 1e-21 UniRef50_Q2J4I2 Cluster: Cytochrome P450; n=2; Frankia|Rep: Cyto... 106 1e-21 UniRef50_Q1ZXL9 Cluster: Cytochrome P450 family protein; n=2; Di... 106 1e-21 UniRef50_Q9V4U7 Cluster: Probable cytochrome P450 6a14; n=10; Sc... 106 1e-21 UniRef50_UPI0000DB6D9C Cluster: PREDICTED: similar to Cytochrome... 106 2e-21 UniRef50_UPI0000D56516 Cluster: PREDICTED: similar to Probable c... 106 2e-21 UniRef50_Q0LK65 Cluster: Cytochrome P450; n=1; Herpetosiphon aur... 106 2e-21 UniRef50_A1HDJ4 Cluster: Cytochrome P450; n=4; Burkholderiaceae|... 106 2e-21 UniRef50_Q5W1K8 Cluster: Cytochrome P450 CYP6AX1 protein; n=2; H... 106 2e-21 UniRef50_Q16FQ1 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep... 106 2e-21 UniRef50_Q4SQM7 Cluster: Chromosome 17 SCAF14532, whole genome s... 105 2e-21 UniRef50_A0YW07 Cluster: Cytochrome P450 hydroxylase; n=1; Lyngb... 105 2e-21 UniRef50_A0Y8J6 Cluster: Probable bifunctional P-450:NADPH-P450 ... 105 2e-21 UniRef50_A5YU13 Cluster: CYP97C3; n=1; Chlamydomonas reinhardtii... 105 2e-21 UniRef50_Q121J8 Cluster: Cytochrome P450; n=2; Comamonadaceae|Re... 105 3e-21 UniRef50_A3VL14 Cluster: Possible cytochrome P450 hydroxylase su... 105 3e-21 UniRef50_Q17BD6 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 105 3e-21 UniRef50_UPI0000E4963D Cluster: PREDICTED: similar to cytochrome... 105 4e-21 UniRef50_A5YU14 Cluster: CYP97A5; n=4; Chlorophyta|Rep: CYP97A5 ... 105 4e-21 UniRef50_Q7QH22 Cluster: ENSANGP00000012679; n=5; Cellia|Rep: EN... 105 4e-21 UniRef50_Q52S21 Cluster: Cytochrome P450; n=3; Plutella xylostel... 105 4e-21 UniRef50_Q00G65 Cluster: Midgut-specific cytochrome P450; n=2; I... 104 5e-21 UniRef50_P30608 Cluster: Cytochrome P450 52A6; n=19; Saccharomyc... 104 5e-21 UniRef50_UPI0000D577EE Cluster: PREDICTED: similar to Probable c... 104 6e-21 UniRef50_UPI0000D561ED Cluster: PREDICTED: similar to Probable c... 104 6e-21 UniRef50_A3RIC1 Cluster: Cytochrome P450; n=1; Bombyx mori|Rep: ... 104 6e-21 UniRef50_Q56VS2 Cluster: Cytochrome P450 monooxygenase pc-3; n=2... 104 6e-21 UniRef50_Q9V675 Cluster: Probable cytochrome P450 6g2; n=2; Soph... 104 6e-21 UniRef50_UPI00015A5D7D Cluster: hypothetical protein LOC10003739... 103 8e-21 UniRef50_Q39NW6 Cluster: Cytochrome P450; n=1; Burkholderia sp. ... 103 8e-21 UniRef50_Q8KUI0 Cluster: Cytochrome P450; n=1; Actinosynnema pre... 103 8e-21 UniRef50_A1W125 Cluster: Cytochrome P450 family protein; n=12; C... 103 8e-21 UniRef50_P82711 Cluster: Probable cytochrome P450 6a19; n=11; Dr... 103 8e-21 UniRef50_Q8T5C1 Cluster: Cytochrome P450 monooxygenase CYP6X1v1;... 103 1e-20 UniRef50_Q86GR1 Cluster: Cytochrome P450 CYPm3r5; n=12; Culicida... 103 1e-20 UniRef50_Q4Q2L1 Cluster: Cytochrome p450-like protein; n=4; Leis... 103 1e-20 UniRef50_Q3I417 Cluster: Cytochrome P450; n=4; Cucujiformia|Rep:... 103 1e-20 UniRef50_Q8NJK3 Cluster: Cytochrome P450 monooxygenase pc-2; n=7... 103 1e-20 UniRef50_P37122 Cluster: Cytochrome P450 76A2; n=10; Spermatophy... 103 1e-20 UniRef50_Q9V769 Cluster: Cytochrome P450 6a22; n=2; Sophophora|R... 103 1e-20 UniRef50_Q3E1G3 Cluster: Cytochrome P450; n=2; Chloroflexus|Rep:... 103 1e-20 UniRef50_Q4H2B4 Cluster: Cytochrome P450 monooxygenase; n=2; Bas... 103 1e-20 UniRef50_Q2GUJ4 Cluster: Putative uncharacterized protein; n=2; ... 103 1e-20 UniRef50_Q82IY3 Cluster: Pentalenene C13 hydroxylase; cytochrome... 102 2e-20 UniRef50_Q162V4 Cluster: Cytochrome P450 family protein, putativ... 102 2e-20 UniRef50_A6G220 Cluster: Cytochrome P450; n=1; Plesiocystis paci... 102 2e-20 UniRef50_A1ZZK3 Cluster: Cytochrome P450 4A10; n=1; Microscilla ... 102 2e-20 UniRef50_P98186 Cluster: Cytochrome P450; n=1; Rhipicephalus mic... 102 2e-20 UniRef50_A7SWV9 Cluster: Predicted protein; n=1; Nematostella ve... 102 2e-20 UniRef50_UPI0000D56CEB Cluster: PREDICTED: similar to Probable c... 102 3e-20 UniRef50_A3Q0Q7 Cluster: Cytochrome P450 precursor; n=3; Mycobac... 102 3e-20 UniRef50_A5BGU6 Cluster: Putative uncharacterized protein; n=1; ... 102 3e-20 UniRef50_Q174T2 Cluster: Cytochrome P450; n=13; Aedes aegypti|Re... 102 3e-20 UniRef50_A6FMY4 Cluster: Cytochrome P450; n=12; Rhodobacterales|... 101 3e-20 UniRef50_A1ZCF9 Cluster: Cytochrome P450, putative; n=1; Microsc... 101 3e-20 UniRef50_Q9ASR3 Cluster: At2g46960/F14M4.21; n=7; core eudicotyl... 101 3e-20 UniRef50_Q5XNT3 Cluster: Cytochrome P450; n=2; Anopheles gambiae... 101 3e-20 UniRef50_Q16F55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 101 3e-20 UniRef50_A7SKW0 Cluster: Predicted protein; n=6; Nematostella ve... 101 3e-20 UniRef50_Q7SY18 Cluster: Zgc:63602; n=2; Danio rerio|Rep: Zgc:63... 101 4e-20 UniRef50_Q9Y6A2 Cluster: Cytochrome P450 46A1; n=22; Amniota|Rep... 101 4e-20 UniRef50_Q9VHP4 Cluster: Probable cytochrome P450 313b1; n=2; So... 101 4e-20 UniRef50_A5NX46 Cluster: Cytochrome P450; n=2; Alphaproteobacter... 101 6e-20 UniRef50_Q27693 Cluster: Cytochrome P450; n=2; Musca domestica|R... 101 6e-20 UniRef50_UPI00015B60BE Cluster: PREDICTED: similar to cytochrome... 100 8e-20 UniRef50_UPI000038DD76 Cluster: COG2124: Cytochrome P450; n=1; N... 100 8e-20 UniRef50_Q9AXM6 Cluster: Taxane 10-beta-hydroxylase; n=16; Eukar... 100 8e-20 UniRef50_UPI00015B62A7 Cluster: PREDICTED: similar to cytochrome... 100 1e-19 UniRef50_UPI0000E48111 Cluster: PREDICTED: similar to cytochrome... 100 1e-19 UniRef50_UPI0000DB77A2 Cluster: PREDICTED: similar to Probable c... 100 1e-19 UniRef50_A4FHE9 Cluster: Bifunctional P-450:NADPH-P450 reductase... 100 1e-19 UniRef50_Q9LUD2 Cluster: Cytochrome P450; n=6; core eudicotyledo... 100 1e-19 UniRef50_Q0U771 Cluster: Putative uncharacterized protein; n=3; ... 100 1e-19 UniRef50_P13527 Cluster: Cytochrome P450 6A1; n=3; Musca domesti... 100 1e-19 UniRef50_UPI0000D56E81 Cluster: PREDICTED: similar to Probable c... 99 1e-19 UniRef50_Q1YFK2 Cluster: Cytochrome P450; n=1; Aurantimonas sp. ... 99 1e-19 UniRef50_Q11B49 Cluster: Cytochrome P450; n=8; Rhizobiales|Rep: ... 99 1e-19 UniRef50_Q0GK98 Cluster: Cytochrome P450 CYP3-like member 4; n=3... 99 1e-19 UniRef50_Q92045 Cluster: Cytochrome P450 11A1, mitochondrial pre... 99 1e-19 UniRef50_UPI00015B5C73 Cluster: PREDICTED: similar to cytochrome... 100 2e-19 UniRef50_Q2L6E2 Cluster: P450; n=1; Streptomyces sp. KO-3988|Rep... 100 2e-19 UniRef50_A7DAQ3 Cluster: Cytochrome P450; n=2; Methylobacterium ... 100 2e-19 UniRef50_A7T0U5 Cluster: Predicted protein; n=2; Nematostella ve... 100 2e-19 UniRef50_Q66JP5 Cluster: Cytochrome P450, family 2, subfamily j,... 99 2e-19 UniRef50_Q603T8 Cluster: Cytochrome P450 51; n=1; Methylococcus ... 99 2e-19 UniRef50_Q9SCP8 Cluster: Cytochrom P450-like protein; n=12; Magn... 99 2e-19 UniRef50_Q9LUC8 Cluster: Cytochrome P450; n=84; Magnoliophyta|Re... 99 2e-19 UniRef50_UPI0000E49A50 Cluster: PREDICTED: hypothetical protein;... 99 3e-19 UniRef50_UPI00003BFC2E Cluster: PREDICTED: similar to Probable c... 99 3e-19 UniRef50_Q05047 Cluster: Cytochrome P450 72A1; n=10; core eudico... 99 3e-19 UniRef50_Q6DHE1 Cluster: Zgc:109896 protein; n=20; Euteleostomi|... 98 4e-19 UniRef50_A6G0E4 Cluster: Cytochrome P450 51; n=1; Plesiocystis p... 98 4e-19 UniRef50_A5HKL8 Cluster: Cytochrome P450 CYP9A22; n=5; Ditrysia|... 98 4e-19 UniRef50_Q2TW05 Cluster: Cytochrome P450 CYP4/CYP19/CYP26 subfam... 98 4e-19 UniRef50_O74131 Cluster: Cytochrome P450 52; n=6; Yarrowia lipol... 98 4e-19 UniRef50_UPI0000D559EB Cluster: PREDICTED: similar to Probable c... 98 6e-19 UniRef50_UPI0000D9A6B6 Cluster: PREDICTED: similar to Cytochrome... 97 7e-19 UniRef50_Q0LJ67 Cluster: Cytochrome P450; n=2; cellular organism... 97 7e-19 UniRef50_Q2LAK7 Cluster: Cytochrome P450 monooxygenase CYP72A67;... 97 7e-19 UniRef50_Q16L53 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep... 97 7e-19 UniRef50_UPI00015B6122 Cluster: PREDICTED: similar to cytochrome... 97 1e-18 UniRef50_UPI00015B480D Cluster: PREDICTED: similar to cytochrome... 97 1e-18 UniRef50_UPI0000DB76BC Cluster: PREDICTED: similar to Probable c... 97 1e-18 UniRef50_UPI0000D561F4 Cluster: PREDICTED: similar to Cytochrome... 97 1e-18 UniRef50_A6FXD3 Cluster: Cytochrome P450 family protein; n=1; Pl... 97 1e-18 UniRef50_O48925 Cluster: CYP82C1p; n=5; core eudicotyledons|Rep:... 97 1e-18 UniRef50_Q8T631 Cluster: Cytochrome P450 CYP6Z1; n=20; Culicidae... 97 1e-18 UniRef50_Q3I415 Cluster: Cytochrome P450; n=1; Leptinotarsa dece... 97 1e-18 UniRef50_Q55AJ4 Cluster: Cytochrome P450 family protein; n=2; Di... 97 1e-18 UniRef50_Q16FW7 Cluster: Cytochrome P450; n=16; Culicidae|Rep: C... 97 1e-18 UniRef50_A5JM35 Cluster: Cytochrome P450 Cyp6AU1; n=1; Bombyx mo... 97 1e-18 UniRef50_Q59990 Cluster: Putative cytochrome P450 120; n=8; Cyan... 97 1e-18 UniRef50_P82712 Cluster: Probable cytochrome P450 12d1 proximal,... 97 1e-18 UniRef50_UPI00015B595F Cluster: PREDICTED: similar to cytochrome... 96 2e-18 UniRef50_A6G6Z8 Cluster: Cytochrome P450; n=1; Plesiocystis paci... 96 2e-18 UniRef50_Q069I9 Cluster: Gossypol-induced cytochrome P450; n=9; ... 96 2e-18 UniRef50_A7S334 Cluster: Predicted protein; n=3; Nematostella ve... 96 2e-18 UniRef50_Q2UI50 Cluster: Cytochrome P450 CYP4/CYP19/CYP26 subfam... 96 2e-18 UniRef50_Q5UXK0 Cluster: Cytochrome P450; n=1; Haloarcula marism... 96 2e-18 UniRef50_A6G8E6 Cluster: Cytochrome P450; n=1; Plesiocystis paci... 96 2e-18 UniRef50_A6CJ44 Cluster: Cytochrome P450 hydroxylase; n=1; Bacil... 96 2e-18 UniRef50_Q9ZW95 Cluster: F5A8.3 protein; n=1; Arabidopsis thalia... 96 2e-18 UniRef50_A7SF10 Cluster: Predicted protein; n=1; Nematostella ve... 96 2e-18 UniRef50_A2QLX8 Cluster: Contig An07c0010, complete genome; n=1;... 96 2e-18 UniRef50_O43174 Cluster: Cytochrome P450 26A1; n=40; Euteleostom... 96 2e-18 UniRef50_UPI0000E480BF Cluster: PREDICTED: similar to cytochrome... 95 3e-18 UniRef50_Q9GTL1 Cluster: Putative cytochrome P450 monooxigenase;... 95 3e-18 UniRef50_Q9V9L1 Cluster: Probable cytochrome P450 6w1; n=3; Dros... 95 3e-18 UniRef50_UPI0000E4A2FC Cluster: PREDICTED: hypothetical protein;... 95 4e-18 UniRef50_UPI0000E49151 Cluster: PREDICTED: similar to cytochrome... 95 4e-18 UniRef50_UPI0000D56E84 Cluster: PREDICTED: similar to Probable c... 95 4e-18 UniRef50_Q5KSN6 Cluster: Putative P450; n=1; Streptomyces sp. KO... 95 4e-18 UniRef50_A5NYU6 Cluster: Cytochrome P450; n=1; Methylobacterium ... 95 4e-18 UniRef50_Q9LUD1 Cluster: Cytochrome P450-like protein; n=1; Arab... 95 4e-18 UniRef50_A7PQ75 Cluster: Chromosome chr18 scaffold_24, whole gen... 95 4e-18 UniRef50_A1XEM0 Cluster: CYP82E8; n=22; Nicotiana|Rep: CYP82E8 -... 95 4e-18 UniRef50_Q6R7M4 Cluster: Cytochrome P450 CYP15A1; n=2; Neoptera|... 95 4e-18 UniRef50_Q174T6 Cluster: Cytochrome P450; n=6; Culicidae|Rep: Cy... 95 4e-18 UniRef50_UPI00015B6167 Cluster: PREDICTED: similar to cytochrome... 95 5e-18 UniRef50_Q7PIH2 Cluster: ENSANGP00000024048; n=1; Anopheles gamb... 95 5e-18 UniRef50_A7RPN7 Cluster: Predicted protein; n=1; Nematostella ve... 95 5e-18 UniRef50_P51589 Cluster: Cytochrome P450 2J2; n=55; Theria|Rep: ... 95 5e-18 UniRef50_UPI00015B46F7 Cluster: PREDICTED: similar to Cyp6g1; n=... 94 7e-18 UniRef50_A7U483 Cluster: Cytochrome P450 family 17 polypeptide 2... 94 7e-18 UniRef50_A7PEY9 Cluster: Chromosome chr11 scaffold_13, whole gen... 94 7e-18 UniRef50_Q5B6B3 Cluster: Cytochrome P450 52; n=5; Eurotiomycetid... 94 7e-18 UniRef50_P24557 Cluster: Thromboxane-A synthase; n=40; Tetrapoda... 94 7e-18 UniRef50_Q7Z449 Cluster: Cytochrome P450 2U1; n=25; Euteleostomi... 94 7e-18 UniRef50_Q6VVX0 Cluster: Cytochrome P450 2R1; n=28; cellular org... 94 7e-18 UniRef50_UPI00015B569B Cluster: PREDICTED: similar to cytochrome... 94 9e-18 UniRef50_Q6AX26 Cluster: MGC86342 protein; n=2; Xenopus|Rep: MGC... 94 9e-18 UniRef50_Q89VZ9 Cluster: Bll0894 protein; n=13; Alphaproteobacte... 94 9e-18 UniRef50_Q82IV2 Cluster: Cytochrome P450 hydroxylase; n=2; Strep... 94 9e-18 UniRef50_Q0S645 Cluster: Cytochrome P450 CYP136; n=4; Actinomyce... 94 9e-18 UniRef50_A4A9V8 Cluster: Cytochrome P450; n=4; Bacteria|Rep: Cyt... 94 9e-18 UniRef50_Q9FF18 Cluster: Cytochrome P450-like protein; n=9; Magn... 94 9e-18 UniRef50_Q2VPT6 Cluster: Cytochrome P450 CYP6P1; n=21; Neoptera|... 94 9e-18 UniRef50_UPI0000DB6FEA Cluster: PREDICTED: similar to Probable c... 93 1e-17 UniRef50_O81653 Cluster: Senescence-associated protein 3; n=1; H... 93 1e-17 UniRef50_Q8WQN0 Cluster: Cytochrome P450 CYP6S2; n=6; Culicidae|... 93 1e-17 UniRef50_Q6JEK3 Cluster: 14a demethylase; n=1; Strongylocentrotu... 93 1e-17 UniRef50_A1CS83 Cluster: NADPH cytochrome P450; n=1; Aspergillus... 93 1e-17 UniRef50_UPI0000E49F6F Cluster: PREDICTED: similar to cytochrome... 93 2e-17 UniRef50_Q9FL55 Cluster: Cytochrome P450-like protein; n=2; Arab... 93 2e-17 UniRef50_A3B3X2 Cluster: Putative uncharacterized protein; n=3; ... 93 2e-17 UniRef50_A1XEH2 Cluster: CYP82M1v1; n=5; Nicotiana tabacum|Rep: ... 93 2e-17 UniRef50_Q5XNU2 Cluster: Cytochrome P450; n=3; Culicidae|Rep: Cy... 93 2e-17 UniRef50_Q2HFV6 Cluster: Putative uncharacterized protein; n=1; ... 93 2e-17 UniRef50_Q0ASD0 Cluster: Cytochrome P450; n=1; Maricaulis maris ... 93 2e-17 UniRef50_Q9Y1L1 Cluster: Ecdysone 20 hydroxylase; n=1; Locusta m... 93 2e-17 UniRef50_Q86QN2 Cluster: Cytochrome P450 CYP12F1; n=15; Culicida... 93 2e-17 UniRef50_Q5XM71 Cluster: Cytochrome P450; n=2; Anopheles gambiae... 93 2e-17 UniRef50_A7RT69 Cluster: Predicted protein; n=1; Nematostella ve... 93 2e-17 UniRef50_Q9V6H1 Cluster: Probable cytochrome P450 9h1; n=3; Soph... 93 2e-17 UniRef50_Q9V676 Cluster: Probable cytochrome P450 6t3; n=3; Soph... 93 2e-17 UniRef50_P95099 Cluster: Putative cytochrome P450 136; n=15; Myc... 93 2e-17 UniRef50_UPI00015B513C Cluster: PREDICTED: similar to cytochrome... 92 3e-17 UniRef50_UPI000038CD69 Cluster: COG2124: Cytochrome P450; n=1; N... 92 3e-17 UniRef50_Q5Z0Q8 Cluster: Cytochrome P450 monooxygenase; n=6; Cor... 92 3e-17 UniRef50_A4BWJ8 Cluster: Cytochrome P450; n=6; Bacteroidetes|Rep... 92 3e-17 UniRef50_A2YMR4 Cluster: Putative uncharacterized protein; n=3; ... 92 3e-17 UniRef50_A6SJT4 Cluster: Putative uncharacterized protein; n=2; ... 92 3e-17 UniRef50_P05093 Cluster: Cytochrome P450 17A1; n=46; Amniota|Rep... 92 3e-17 UniRef50_UPI00015B4ED4 Cluster: PREDICTED: similar to cytochrome... 92 4e-17 UniRef50_UPI00003C05B8 Cluster: PREDICTED: similar to Probable c... 92 4e-17 UniRef50_Q9AVM3 Cluster: Cytochrome P450; n=7; BEP clade|Rep: Cy... 92 4e-17 UniRef50_A4QQR9 Cluster: Putative uncharacterized protein; n=6; ... 92 4e-17 UniRef50_Q964Q7 Cluster: Cytochrome P450 6d3; n=9; Schizophora|R... 92 4e-17 UniRef50_Q94EV6 Cluster: Cytochrome P450; n=19; Poaceae|Rep: Cyt... 91 5e-17 UniRef50_Q2UT03 Cluster: Cytochrome P450 52; n=6; Trichocomaceae... 91 5e-17 UniRef50_Q9VRI9 Cluster: Probable cytochrome P450 6t1; n=1; Dros... 91 5e-17 UniRef50_Q6PA33 Cluster: MGC68652 protein; n=9; Xenopus|Rep: MGC... 91 6e-17 UniRef50_Q4SI76 Cluster: Chromosome 5 SCAF14581, whole genome sh... 91 6e-17 UniRef50_Q9X7G9 Cluster: Cytochrome P450 hydroxylase; n=2; Myxoc... 91 6e-17 UniRef50_Q17GV0 Cluster: Cytochrome P450; n=4; Aedes aegypti|Rep... 91 6e-17 UniRef50_Q9P493 Cluster: Cytochrome P-450 cyp509A1; n=1; Cunning... 91 6e-17 UniRef50_P0A513 Cluster: Cytochrome P450 51; n=19; Corynebacteri... 91 6e-17 UniRef50_P33261 Cluster: Cytochrome P450 2C19 (EC 1.14.13.80) ((... 91 6e-17 UniRef50_UPI00015B5A0F Cluster: PREDICTED: similar to cytochrome... 91 8e-17 UniRef50_UPI0000D55B02 Cluster: PREDICTED: similar to Probable c... 91 8e-17 UniRef50_Q9RTN4 Cluster: Cytochrome P450; n=1; Deinococcus radio... 91 8e-17 UniRef50_Q6NCP8 Cluster: Possible cytochrome P450 hydroxylase su... 91 8e-17 UniRef50_Q26HX2 Cluster: Cytochrome P450 hydroxylase; n=1; Flavo... 91 8e-17 UniRef50_Q0DIA1 Cluster: Os05g0405500 protein; n=4; Oryza sativa... 91 8e-17 UniRef50_Q55W77 Cluster: Putative uncharacterized protein; n=2; ... 91 8e-17 UniRef50_Q9V674 Cluster: Cytochrome P450 6g1; n=16; Schizophora|... 91 8e-17 UniRef50_UPI0000F2BC00 Cluster: PREDICTED: similar to CYP2J4; n=... 90 1e-16 UniRef50_Q31NH2 Cluster: Cytochrome P450; n=2; Synechococcus elo... 90 1e-16 UniRef50_A4PBE8 Cluster: Cytochrome P450 enzyme; n=9; Magnolioph... 90 1e-16 UniRef50_A6S200 Cluster: Putative uncharacterized protein; n=1; ... 90 1e-16 UniRef50_A1C5L5 Cluster: Cytochrome P450 oxidoreductase, putativ... 90 1e-16 UniRef50_UPI0000E251E4 Cluster: PREDICTED: similar to cytochrome... 90 1e-16 UniRef50_Q2LAL2 Cluster: Cytochrome P450 monooxygenase CYP76O2; ... 90 1e-16 UniRef50_Q0E2P9 Cluster: Os02g0221900 protein; n=15; Magnoliophy... 90 1e-16 UniRef50_Q0CQY1 Cluster: Cytochrome P450 52; n=1; Aspergillus te... 90 1e-16 UniRef50_A2QVX7 Cluster: Remark: astaxanthin is a ketocarotenoid... 90 1e-16 UniRef50_P20853 Cluster: Cytochrome P450 2A7; n=156; Euteleostom... 90 1e-16 UniRef50_P48420 Cluster: Cytochrome P450 78A1; n=19; Spermatophy... 90 1e-16 UniRef50_UPI0000E47585 Cluster: PREDICTED: similar to cytochrome... 89 2e-16 UniRef50_UPI0000D56374 Cluster: PREDICTED: similar to Cytochrome... 89 2e-16 UniRef50_Q7SXE6 Cluster: LOC402831 protein; n=17; Euteleostomi|R... 89 2e-16 UniRef50_Q54SK0 Cluster: Cytochrome P450 family protein; n=1; Di... 89 2e-16 UniRef50_A1CIZ0 Cluster: Cytochrome P450; n=1; Aspergillus clava... 89 2e-16 UniRef50_Q96SQ9 Cluster: Cytochrome P450 2S1; n=12; Theria|Rep: ... 89 2e-16 UniRef50_P08683 Cluster: Cytochrome P450 2C11 (EC 1.14.14.1) (CY... 89 2e-16 UniRef50_UPI0000E4A8EA Cluster: PREDICTED: similar to GA15235-PA... 89 3e-16 UniRef50_UPI0000E49222 Cluster: PREDICTED: similar to CYP4BB1 is... 89 3e-16 UniRef50_A0GM07 Cluster: Cytochrome P450; n=1; Burkholderia phyt... 89 3e-16 UniRef50_A7S7K8 Cluster: Predicted protein; n=1; Nematostella ve... 89 3e-16 UniRef50_Q66ZJ5 Cluster: Cytochrome P450; n=5; Homo/Pan/Gorilla ... 89 3e-16 UniRef50_P29980 Cluster: Probable cytochrome P450 110; n=2; Nost... 89 3e-16 UniRef50_UPI0000E4A41F Cluster: PREDICTED: hypothetical protein;... 89 3e-16 UniRef50_UPI0000D6651A Cluster: PREDICTED: similar to Cytochrome... 89 3e-16 UniRef50_Q4UXF7 Cluster: Cytochrome P450 hydroxylase; n=2; Xanth... 89 3e-16 UniRef50_Q25AL2 Cluster: H0102C09.4 protein; n=7; Oryza sativa|R... 89 3e-16 UniRef50_A7R5U7 Cluster: Chromosome undetermined scaffold_1067, ... 89 3e-16 UniRef50_Q16FQ2 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 89 3e-16 UniRef50_A0A8M4 Cluster: Cytochrome P450 314 family; n=1; Daphni... 89 3e-16 UniRef50_O13820 Cluster: C-22 sterol desaturase Erg5; n=11; Asco... 89 3e-16 UniRef50_A6RAM5 Cluster: Cytochrome P450 61; n=3; Pezizomycotina... 89 3e-16 UniRef50_O48927 Cluster: Cytochrome P450 78A3; n=7; core eudicot... 89 3e-16 UniRef50_Q42716 Cluster: Cytochrome P450 71A8; n=1; Mentha x pip... 89 3e-16 UniRef50_Q8YQS3 Cluster: Cytochrome P450; n=7; Cyanobacteria|Rep... 88 4e-16 UniRef50_Q9SZ46 Cluster: Cytochrome P450-like protein; n=11; cor... 88 4e-16 UniRef50_Q1PEI9 Cluster: Cytochrome P450 family protein; n=2; Ar... 88 4e-16 UniRef50_Q5XNT0 Cluster: Cytochrome P450; n=4; Culicidae|Rep: Cy... 88 4e-16 UniRef50_Q0P0N3 Cluster: Aromatase; n=4; Branchiostoma|Rep: Arom... 88 4e-16 UniRef50_Q0GBX4 Cluster: Cytochrome P450 CYP3-like member 1; n=1... 88 4e-16 UniRef50_A5JTS8 Cluster: Cytochrome P450; n=7; Ditrysia|Rep: Cyt... 88 4e-16 UniRef50_Q9SD85 Cluster: Flavonoid 3'-monooxygenase; n=66; Magno... 88 4e-16 UniRef50_UPI0000E4A420 Cluster: PREDICTED: similar to MGC140497 ... 88 6e-16 UniRef50_Q8YMU4 Cluster: Cytochrome P450; n=10; Cyanobacteria|Re... 88 6e-16 UniRef50_A6FYS5 Cluster: Possible cytochrome P450 hydroxylase su... 88 6e-16 UniRef50_Q9SML3 Cluster: Cytochrome P450 monooxygenase; n=1; Cic... 88 6e-16 UniRef50_Q9M4X2 Cluster: Putative cytochrome P450; n=3; Solanace... 88 6e-16 UniRef50_Q59I67 Cluster: Flavone synthase II; n=9; asterids|Rep:... 88 6e-16 UniRef50_Q0E4L3 Cluster: Os02g0113200 protein; n=5; Oryza sativa... 88 6e-16 UniRef50_A7PDZ0 Cluster: Chromosome chr11 scaffold_13, whole gen... 88 6e-16 UniRef50_Q7PIP7 Cluster: ENSANGP00000025243; n=6; Culicidae|Rep:... 88 6e-16 UniRef50_Q22Z86 Cluster: Cytochrome P450 family protein; n=1; Te... 88 6e-16 >UniRef50_Q9VYY4 Cluster: Cytochrome P450 4g15; n=8; Neoptera|Rep: Cytochrome P450 4g15 - Drosophila melanogaster (Fruit fly) Length = 574 Score = 605 bits (1493), Expect = e-171 Identities = 290/496 (58%), Positives = 370/496 (74%), Gaps = 26/496 (5%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86 F ++ ++W+G KL+VF+ D D+E++L+SHV+IDKA+EY+FFKPWLG+GLLIS+G KWRS Sbjct: 79 FEHIAKMWIGPKLVVFIYDPRDVELLLSSHVYIDKASEYKFFKPWLGDGLLISTGQKWRS 138 Query: 87 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMG 146 HRK+IAPTFH+N+LKSF+ +FN+NS NVV KL++E G+TFD HDYMS TV+ILLETAMG Sbjct: 139 HRKLIAPTFHLNVLKSFIELFNENSRNVVRKLRAEDGRTFDCHDYMSEATVEILLETAMG 198 Query: 147 ISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTN 206 +S+KTQD+SGF+YAMAVM+MCDI+H RH ++R+E VF LT ++K+Q +LL IIHGLT Sbjct: 199 VSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTRYYKEQGRLLNIIHGLTT 258 Query: 207 KVIKNKKETY----------LENKAKGI------------IPPTL--EEFTHHSGEILAN 242 KVI++KK + E KA + P T +E + A+ Sbjct: 259 KVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTAGSDEKDREKDKEKAS 318 Query: 243 NAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTI 302 LS G +DDLD D ND+GEKKRLAFLDLM+ES+QNG I+D EIKE+VDTI Sbjct: 319 PVAGLSYGQSAGLKDDLDVED-NDIGEKKRLAFLDLMLESAQNGA-LITDTEIKEQVDTI 376 Query: 303 MFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVIL 362 MFEGHDTTAAGSSF L L+GIHQD+Q RV EL IFGDS RPATF DTLEMKYLER ++ Sbjct: 377 MFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQRPATFQDTLEMKYLERCLM 436 Query: 363 ESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNF 422 E+LR+YPPVP+IAR+L D+ +++ NYVIP G TV + T +LHR PK Y +P VF+PDNF Sbjct: 437 ETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNF 496 Query: 423 LPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGD 482 LPE NRHYY+++PFSAGPRSCVGRKYA RN+R S++ E +FKLQ D Sbjct: 497 LPERQANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTESDFKLQAD 556 Query: 483 IILKRAEGFQMKVEPR 498 IILKR EGF+++++PR Sbjct: 557 IILKREEGFRVRLQPR 572 >UniRef50_Q9V3S0 Cluster: Cytochrome P450 4g1; n=62; Protostomia|Rep: Cytochrome P450 4g1 - Drosophila melanogaster (Fruit fly) Length = 556 Score = 515 bits (1271), Expect = e-145 Identities = 251/495 (50%), Positives = 340/495 (68%), Gaps = 14/495 (2%) Query: 6 HVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY 65 HV +++ + LGY +G ++ WLG+ L+VFL + DIE+IL+ H H+ KA EY Sbjct: 70 HVAAGLSNAEILAVGLGYLNKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEY 129 Query: 66 RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT 125 R+FKPW G+GLLIS+G WR HRKMIAPTFH +ILKSFV F +S VV ++ E GK+ Sbjct: 130 RYFKPWFGDGLLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGKS 189 Query: 126 FDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVF 185 FDVHDYMS TTVDILL TAMG+ + + F+YA AV+ MCDIIH+R K R + ++ Sbjct: 190 FDVHDYMSQTTVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIY 249 Query: 186 KLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAK 245 K T ++ +++ II G+T+KV+K++KE + E +++ I+ EE + A+ Sbjct: 250 KFTKLREKGDRMMNIILGMTSKVVKDRKENFQE-ESRAIV----EEISTPVASTPASKK- 303 Query: 246 TLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFE 305 +G RDDLD DENDVG K+RLA LD M+E ++N + ++ +I +EV+TIMFE Sbjct: 304 -------EGLRDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFE 356 Query: 306 GHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD-RPATFADTLEMKYLERVILES 364 GHDTT+AGSSF LC++GIH+D+QA+V+ E IFGD+ R TFADT+EMKYLERVILE+ Sbjct: 357 GHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCTFADTMEMKYLERVILET 416 Query: 365 LRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP 424 LRLYPPVP+IAR+L+ D+ +++ Y +P GTTV++ + +HR+P Y +P F+PDNFLP Sbjct: 417 LRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLP 476 Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDII 484 E NRHYYS+IPFSAGPRSCVGRKYA RN+ S E +FKLQ DII Sbjct: 477 ERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEADFKLQADII 536 Query: 485 LKRAEGFQMKVEPRK 499 LK GF + +E R+ Sbjct: 537 LKLENGFNVSLEKRQ 551 >UniRef50_Q967Y5 Cluster: Cytochrome P450 CYP4G13v2; n=4; Neoptera|Rep: Cytochrome P450 CYP4G13v2 - Musca domestica (House fly) Length = 552 Score = 496 bits (1223), Expect = e-139 Identities = 246/472 (52%), Positives = 317/472 (67%), Gaps = 13/472 (2%) Query: 28 GNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSH 87 G +R+ LG +VFL + D+EI LN + H++K+ EYR+F+PW G GLLIS G WR H Sbjct: 88 GETVRILLGHMNVVFLTNPADLEIFLNGYKHLEKSVEYRYFQPWFGNGLLISKGHHWRHH 147 Query: 88 RKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGI 147 RKMIAPTFH +ILKSFV F ++S V + S+VG+ FD H YMS TTVDILL TAMG Sbjct: 148 RKMIAPTFHQSILKSFVPTFVKHSKAVSGRFASKVGQEFDCHKYMSETTVDILLTTAMGC 207 Query: 148 SRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNK 207 + + E +YA AVM MCDIIH R K + R + + T + KL+ +I +T K Sbjct: 208 KVQPETEKSAEYAQAVMDMCDIIHIRQLKLFYRLDSTIRFTKLREHDNKLMNVILSMTRK 267 Query: 208 VIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDV 267 V++++K+ + + +GI+ T E+ ++ A AK +G RDDLD DEND+ Sbjct: 268 VVEDRKKNF-NAEERGIVDRTAED-----AKLKAKAAKK------EGLRDDLDDIDENDI 315 Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327 GEK+RLA LD M+E +N K +D ++ +EV+TIMFEGHDTTAAGSSF LC+LGIHQDV Sbjct: 316 GEKRRLALLDAMMEMEKNPDIKWTDKDVMDEVNTIMFEGHDTTAAGSSFALCMLGIHQDV 375 Query: 328 QARVYDELYQIFGDS-DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386 Q RV++E IFGD +R TFADTL+M YLERVI E+ RL+PPVP+IARK DV + + Sbjct: 376 QQRVFEEQQAIFGDDLNRDCTFADTLQMSYLERVICETQRLFPPVPLIARKAEEDVNLKS 435 Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446 Y I GTTVV+ + +HR+ Y DPE FNPDNFLPE T NRHYY+YIPFSAGPRSCV Sbjct: 436 GPYTIAKGTTVVLLQYFVHRRADIYPDPEKFNPDNFLPERTANRHYYAYIPFSAGPRSCV 495 Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 GRK+A RN+R S +K+F+LQGDIILK A GF + +E R Sbjct: 496 GRKFAMLQLKVLLSTIIRNYRVSSTRTQKDFQLQGDIILKMANGFNITLEKR 547 >UniRef50_A0A8M5 Cluster: Cytochrome P450 4 family; n=1; Daphnia magna|Rep: Cytochrome P450 4 family - Daphnia magna Length = 526 Score = 363 bits (894), Expect = 4e-99 Identities = 201/494 (40%), Positives = 291/494 (58%), Gaps = 42/494 (8%) Query: 14 QKLVNLALGYAQTFGN-----VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFF 68 ++++NL L FG +IR W+G + F A+ +E +L+S+ I K+ EY F Sbjct: 67 EEIMNLLLLLHVVFGRLSPSGIIRAWIGPLPMFFATTAEAVEAVLSSNKIITKSREYDFL 126 Query: 69 KPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDV 128 PWL GLL S+G KW++ RK++ P FH IL+ FV +FN+ S +V KL V K D+ Sbjct: 127 HPWLNTGLLTSTGSKWQTRRKLLTPAFHFKILEDFVHVFNEQSLILVNKLNQAVAKDKDL 186 Query: 129 H--DYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFK 186 + +++ T+DI+ ETAMG + + Q ++ Y AV M +I R +F++ + +FK Sbjct: 187 NIFPFVTLCTLDIICETAMGRNVEAQSKTDSAYVQAVYNMSQLIQHRQVRFYLWLDWMFK 246 Query: 187 LTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKT 246 L+S + +Q K LGI+HG TNKVI+ E KA E S +I + Sbjct: 247 LSSHWPEQRKTLGILHGFTNKVIQ-------ERKA---------EHQQRSSDIAEPSKDV 290 Query: 247 LSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEG 306 D VF K+RLAFLDL+IE SQ GT +S +I+EEVDT MFEG Sbjct: 291 TEDAVFS----------------KRRLAFLDLLIEFSQGGT-VLSASDIREEVDTFMFEG 333 Query: 307 HDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLR 366 HDTT+A ++ + L+G H +VQ V +EL ++FGDSDRPAT AD E+KYLE + E+LR Sbjct: 334 HDTTSAAITWSIFLIGSHPEVQEMVNEELDRVFGDSDRPATMADLSELKYLECCVKEALR 393 Query: 367 LYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPEN 426 LYP VP+I+R D I IPAGT+V I ++ LHR PKY+ DPE++ P FL E+ Sbjct: 394 LYPSVPIISRTCVEDTVIGGDE--IPAGTSVSICSYYLHRDPKYFPDPELYQPKRFLAEH 451 Query: 427 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486 + RH YSY+PFSAGPR+C+G+++A RNF S +E L ++IL+ Sbjct: 452 AERRHPYSYVPFSAGPRNCIGQRFALMEEKAVLSAILRNFHVQSLDKREEIILLAELILR 511 Query: 487 RAEGFQMKVEPRKR 500 +G ++++EP+K+ Sbjct: 512 PRDGIRVRLEPKKK 525 >UniRef50_Q9VA27 Cluster: Cytochrome P450 4c3; n=15; Coelomata|Rep: Cytochrome P450 4c3 - Drosophila melanogaster (Fruit fly) Length = 535 Score = 363 bits (892), Expect = 8e-99 Identities = 197/498 (39%), Positives = 295/498 (59%), Gaps = 36/498 (7%) Query: 3 LNIHVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKA 62 + ++V + L +++ + + G + RVW G+ V L + + +E ILNS ++K+ Sbjct: 71 IEMNVDHDELFNRVIGMQKLWGTRIG-INRVWQGTAPRVLLFEPETVEPILNSQKFVNKS 129 Query: 63 TEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV 122 +Y + PWLGEGLL S+ KW S RK++ P FH IL F+ +FN+ S + KL EV Sbjct: 130 HDYDYLHPWLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEV 189 Query: 123 G-KTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRS 181 G + F++ Y++ T+DI+ ETAMG Q S +Y AV + I+ R K W++S Sbjct: 190 GSEAFNLFPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQS 249 Query: 182 EIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILA 241 + +F LT+ +K + +HG +N VI+ E KA+ I L+E +++ Sbjct: 250 DFIFSLTAEYKLHQSYINTLHGFSNMVIR-------ERKAELAI---LQENNNNNN---- 295 Query: 242 NNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDT 301 NNA D DVG+KKRLAFLDL+I++S+ GT +S+ +I+EEVDT Sbjct: 296 NNAPDAYD----------------DVGKKKRLAFLDLLIDASKEGT-VLSNEDIREEVDT 338 Query: 302 IMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDS-DRPATFADTLEMKYLERV 360 MFEGHDTT+A S+ L LLG H + Q RV +EL IFGD + PAT + ++M+YLE Sbjct: 339 FMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECC 398 Query: 361 ILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPD 420 I +SLRL+P VP++AR + DV I K ++PAGT +I T+ LHR P+ + PE FNPD Sbjct: 399 IKDSLRLFPSVPMMARMVGEDVNIGGK--IVPAGTQAIIMTYALHRNPRVFPKPEQFNPD 456 Query: 421 NFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQ 480 NFLPEN RH ++YIPFSAGPR+C+G+K+A R ++ + ++ L Sbjct: 457 NFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLL 516 Query: 481 GDIILKRAEGFQMKVEPR 498 G++IL+ +G ++K+ PR Sbjct: 517 GELILRPKDGLRVKITPR 534 >UniRef50_Q170T4 Cluster: Cytochrome P450; n=5; Endopterygota|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 497 Score = 318 bits (781), Expect = 2e-85 Identities = 181/478 (37%), Positives = 269/478 (56%), Gaps = 45/478 (9%) Query: 24 AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK 83 ++ +G + RVW+G++L +F + D E +L+S I K+ Y+F PWLG GLL+S+ K Sbjct: 61 SRKYGTMFRVWVGTRLALFCTNTPDTETVLSSQKLIRKSELYKFLVPWLGNGLLLSTDQK 120 Query: 84 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILLE 142 W + RK+I P FH IL+ F+ +F++ S +V+KLK E GK +V+ Y++ +D++ E Sbjct: 121 WFNKRKIITPAFHFKILEQFIEVFDRQSGILVQKLKPEASGKLVNVYPYVTLCALDVICE 180 Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202 TAMG Q + Y AV ++ ++ R K W RS+ +F L+ K+Q Sbjct: 181 TAMGTPINAQTDVDSKYVRAVTELSYLLTTRFVKVWQRSDFLFNLSPDRKRQ-------- 232 Query: 203 GLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFN 262 +KVIK L +FT + I+ K L D D + Sbjct: 233 ---DKVIK-----------------VLHDFTTN---IIQKRRKELMD------HGDSGIS 263 Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 ++ +G KK++AFLD+++++S +G ++D EI+EEVDT MFEGHDTT +F L LL Sbjct: 264 GDDSIGSKKKMAFLDVLLQASVDG-KPLTDKEIQEEVDTFMFEGHDTTTIAIAFTLLLLA 322 Query: 323 IHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381 H +VQ +VY E+ +I G D PAT+ + +MKYLE VI ESLRLYPPVP+I RK Sbjct: 323 RHPEVQEKVYKEVTEIIGTDLSIPATYRNLQDMKYLEMVIKESLRLYPPVPIIGRKFTEK 382 Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHY-YSYIPFSA 440 TI VIP + +G ++HR PK + DPE F+P+ F PE T + Y+YIPFSA Sbjct: 383 TTIG--GNVIPEDSNFNLGIIVMHRDPKLFDDPEKFDPERFSPERTMEQSSPYAYIPFSA 440 Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 GPR+C+G+K+A RN+R PE + +Q + LK +G ++ PR Sbjct: 441 GPRNCIGQKFAMLELKSTLSKVIRNYRLTEAGPEPQLIIQ--LTLKPKDGLKIAFVPR 496 >UniRef50_Q27589 Cluster: Cytochrome P450 4d2; n=8; Acalyptratae|Rep: Cytochrome P450 4d2 - Drosophila melanogaster (Fruit fly) Length = 501 Score = 299 bits (734), Expect = 1e-79 Identities = 177/475 (37%), Positives = 262/475 (55%), Gaps = 42/475 (8%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86 +G + RVW+ +L VF D DIE +L+S HI K Y+ WLG+GLL+S+G KW Sbjct: 65 YGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHG 124 Query: 87 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKT-FDVHDYMSGTTVDILLETA 144 RK+I PTFH IL+ FV IF+Q S +VE+L+S GKT ++ + T +DI+ ETA Sbjct: 125 RRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGKTPINIFPVICLTALDIIAETA 184 Query: 145 MGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGL 204 MG Q Y AV + +I+ +R W R + +F+LT Q T Sbjct: 185 MGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLT----QPT--------- 231 Query: 205 TNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDE 264 E ++KA ++ E E L NN+K + ++++F Sbjct: 232 ---------EAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTP------EEEVNF--- 273 Query: 265 NDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324 +G+K+R+A LD++++S+ +G +SD +I+EEVDT MFEGHDTT + SF L + H Sbjct: 274 --LGQKRRMALLDVLLQSTIDGA-PLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRH 330 Query: 325 QDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383 +VQ R+ E+ + G D P T D E+K++E VI ESLRL+PPVP+I R DV Sbjct: 331 PEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVE 390 Query: 384 ISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443 I K+ IPAGT +G F+L R P+Y++ P+ F P+ F + H Y+YIPFSAGPR Sbjct: 391 IRGKH--IPAGTNFTMGIFVLLRDPEYFESPDEFRPERF-DADVPQIHPYAYIPFSAGPR 447 Query: 444 SCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 +C+G+K+A R+F + PE + +I+L+ A G + ++PR Sbjct: 448 NCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSM--NIVLRSANGVHLGLKPR 500 >UniRef50_UPI00015B569E Cluster: PREDICTED: similar to cytochrome P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 512 Score = 299 bits (733), Expect = 1e-79 Identities = 165/461 (35%), Positives = 253/461 (54%), Gaps = 40/461 (8%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 ++ W+G++ IV L +E+IL S+ I KA Y + KPWLG+GL+ S+G W SHR+ Sbjct: 73 MVLAWVGTQPIVILRRPQQMEVILPSNTLITKAATYDYMKPWLGDGLVTSTGELWFSHRR 132 Query: 90 MIAPTFHINILKSFVGIFNQN----SNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 145 +I P FH +L+ + + + + +LK++ ++ + T+D + ETAM Sbjct: 133 LITPAFHFGVLEEYGAVMREKVEIFKECIESELKTDPKAPINIFGLVVKYTLDTICETAM 192 Query: 146 GISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205 G++ TQ Y AV + +R YK W++ ++ T+ K+ + I+H T Sbjct: 193 GVNIDTQRNPESAYVKAVHTYARLTVERFYKPWLKWNAIYYRTNKGKEALNAVKIMHSFT 252 Query: 206 NKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDEN 265 KVI+ K+ E K K + K LSD V + Sbjct: 253 EKVIRQKQ---AERKEKSF------------------SNKELSDEV-------------D 278 Query: 266 DVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQ 325 + G++KR AFLDL++ +S+N +N ++ E++EEVDT MF GHDTT++ S+ L L Sbjct: 279 EFGKRKRKAFLDLLLSASENASNPLTFEELREEVDTFMFAGHDTTSSAISWGLFALANAP 338 Query: 326 DVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIS 385 ++QA+V+ EL +IFGDS A E+KYL+RVI E LRLYP P+++R+L D I Sbjct: 339 EIQAKVHKELQEIFGDSGETANSKQLSELKYLDRVIKEVLRLYPSAPMVSRRLTHDTVID 398 Query: 386 TKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSC 445 N+ +P GT V I + +H PK +KDPE F+PD FLPEN ++RH YSY+PFSAGPR+C Sbjct: 399 --NHHVPKGTFVNIHIYQMHHDPKVWKDPETFDPDRFLPENIRSRHPYSYVPFSAGPRNC 456 Query: 446 VGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486 +G+K+A R ++ S + E K+ IL+ Sbjct: 457 IGQKFALLEVKTALTAILRKWQISSVLKPTEIKMIHTFILR 497 >UniRef50_UPI00015B5D09 Cluster: PREDICTED: similar to cytochrome P450 CYP4AB2; n=4; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis Length = 519 Score = 297 bits (730), Expect = 3e-79 Identities = 157/439 (35%), Positives = 251/439 (57%), Gaps = 30/439 (6%) Query: 14 QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLG 73 ++L L + + + + + ++W K ++ ++ DD+E +L S HI+K+ Y PW G Sbjct: 52 EQLWPLGIKWDKQYYPIYKIWTTHKAVIVILHPDDVETLLTSMEHIEKSIMYDMVHPWFG 111 Query: 74 EGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMS 133 GLL S+G KW+ RK++ P FH ++L+ + I +N+ V+ LKS ++ + ++ Sbjct: 112 TGLLTSTGAKWQKRRKILTPAFHFHVLQKYFDIIVENNEKVMHSLKSNGSVINNLVELLT 171 Query: 134 GTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQ 193 T+D++ ETAMG + ++ Y + + + + R + W + + F+ TS ++ Sbjct: 172 YYTLDVICETAMGTTLLDKEHQQ-KYRNVLHDVSNAVIYRLMRPWFQVDWTFRWTSVAEK 230 Query: 194 QTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLS-DTVF 252 Q K L +IHG + K+IK +KE + K KG H+ ++ ++ + D + Sbjct: 231 QKKALEVIHGFSKKIIKERKEYH--EKTKG----------HYLNQLESDQSDDKKEDEEY 278 Query: 253 KGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAA 312 GYR KKRLA LDL+I ++G N+I D I+EEVDT +FEGHDT+A Sbjct: 279 FGYR-------------KKRLAMLDLLIAKQKDG-NQIDDAGIREEVDTFIFEGHDTSAM 324 Query: 313 GSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVP 372 F + L+ H DVQ R+ E+ ++ S+ + ++ YLE I ESLRLYP VP Sbjct: 325 AMCFAILLIAEHNDVQDRIRAEVKEVLEKSEGKMGVPEIQQLNYLELCIKESLRLYPSVP 384 Query: 373 VIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHY 432 I+R + +D+ + KNY++P GT + I F LHR P ++ DPE F+PD FLP+ Q RH Sbjct: 385 FISRGVTKDLHL--KNYIVPKGTLIQINIFSLHRDPNFWPDPEKFDPDRFLPDRFQGRHP 442 Query: 433 YSYIPFSAGPRSCVGRKYA 451 YSYIPFSAGPR+C+G+K+A Sbjct: 443 YSYIPFSAGPRNCIGQKFA 461 >UniRef50_Q6VAB7 Cluster: Cytochrome P450 CYP4AB2; n=6; Apocrita|Rep: Cytochrome P450 CYP4AB2 - Solenopsis invicta (Red imported fire ant) Length = 511 Score = 297 bits (730), Expect = 3e-79 Identities = 171/462 (37%), Positives = 259/462 (56%), Gaps = 38/462 (8%) Query: 40 IVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 99 +VF+ DD+EIILN+ HI K+ Y +PWLG GLL S G KW RK++ PTFH NI Sbjct: 78 LVFIRHPDDLEIILNNTKHISKSNLYDALRPWLGMGLLTSGGSKWHLRRKILTPTFHFNI 137 Query: 100 LKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRKTQDESGFD 158 L+ FV I + ++ LK+ G T D+ ++S T++ + ETAMG S + Sbjct: 138 LQQFVEILIEEGESMTRSLKNAGGTITKDLVPFISEYTLNAICETAMGTSLQEMGSFQQQ 197 Query: 159 YAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLE 218 Y AV +M +++ R + W++ + +F LTS ++Q KLL I+HG T KVI +K+ + Sbjct: 198 YRKAVHRMGELLVYRAMRPWLKYDWIFSLTSKGREQKKLLKILHGFTEKVIAKRKDYHKR 257 Query: 219 NKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVG-EKKRLAFLD 277 K G+ L N K D+ N+ +G +KKR A LD Sbjct: 258 TK----------------GQYLKNLNK------------DVVPNETETIGIKKKRFAMLD 289 Query: 278 LMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ 337 L+I++SQ G ++D +I+EEVDT MFEG DTT F+L LL H+D+Q V E+ Sbjct: 290 LLIQASQEGL--LTDFDIREEVDTFMFEGFDTTGMAMCFILSLLAEHKDIQDCVRKEIDA 347 Query: 338 IFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTV 397 + ++ +++YLER I E+LRLYP V I+R + + + T Y+IPAGT V Sbjct: 348 VMQENQGKLNMKSLQDLQYLERCIKEALRLYPSVYFISRITSEETELKT--YLIPAGTLV 405 Query: 398 VIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXX 457 ++ ++ HR ++ +PEVF+PD FLP+N +NRH YSY+PFSAGPR+C+G+++A Sbjct: 406 ILNFYITHRDSNFWPNPEVFDPDRFLPDNIRNRHPYSYLPFSAGPRNCIGQRFALLELKA 465 Query: 458 XXXXXXRNF--RTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 NF + + + F + D+IL+ + ++K P Sbjct: 466 MLVPLIYNFYLEPVDYLENQRFGI--DMILRSLDPCRLKFVP 505 >UniRef50_A0MNW4 Cluster: Cyp4M9; n=20; Obtectomera|Rep: Cyp4M9 - Bombyx mandarina (Wild silk moth) (Wild silkworm) Length = 505 Score = 288 bits (706), Expect = 3e-76 Identities = 166/479 (34%), Positives = 257/479 (53%), Gaps = 35/479 (7%) Query: 24 AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK 83 A + N+ R W + + D+IE I++S HI K+ Y F WL +GLL+S+G K Sbjct: 61 ATQWPNLNRFWSFGIGALNIYGPDEIEAIISSTQHITKSPVYNFLSDWLRDGLLLSTGTK 120 Query: 84 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLET 143 W+ RK++ P FH N LK F I +NS E LK GK+ +V +S T+ + ET Sbjct: 121 WQKRRKILTPAFHFNTLKQFCVILEENSQRFTENLKDTEGKSINVVPAISEYTLHSICET 180 Query: 144 AMGISRKTQ-DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202 AM ++ E+G Y A+ ++ + R + + ++ L + KQ L I+H Sbjct: 181 AMRTQLGSETSEAGRSYKNAICELGNQFVHRLARIPPHNNFIYNLFTLGKQNEHL-NIVH 239 Query: 203 GLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFN 262 T +VIK++++ + +G NN DT + + FN Sbjct: 240 SFTKRVIKDRRQ-----------------YIRRNG---GNNFDDEKDT--QADEHSIYFN 277 Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 KK+ A LDL++++ ++G I + ++EE+DT MFEGHDTTA G ++ + L+ Sbjct: 278 -------KKKTAMLDLLLKAERDGL--IDEIGVQEEIDTFMFEGHDTTATGLTYCIMLIA 328 Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382 H+ +Q ++ +EL +IFG+S R A D +M+YLER I ESLRLYPPVP + R L+ ++ Sbjct: 329 NHKSIQDKIIEELDEIFGESTRAADIEDLSKMRYLERCIKESLRLYPPVPSMGRILSEEI 388 Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442 ++ Y +PAGT I F LHR+ +KDP VF+PD FLP NT+ RH Y+YIPFSAGP Sbjct: 389 NLN--GYTVPAGTYCHIQIFDLHRREDLFKDPLVFDPDRFLPHNTEGRHPYAYIPFSAGP 446 Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRV 501 R+C+G+K+A R + ++ K D++L+ E ++ R +V Sbjct: 447 RNCIGQKFAILEMKSLLSAVLRRYNLYPITKPEDLKFVLDLVLRTTEPVHVRFVKRNKV 505 >UniRef50_Q9VS79 Cluster: Cytochrome P450 4d8; n=6; Schizophora|Rep: Cytochrome P450 4d8 - Drosophila melanogaster (Fruit fly) Length = 463 Score = 278 bits (682), Expect = 2e-73 Identities = 171/482 (35%), Positives = 264/482 (54%), Gaps = 44/482 (9%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82 Y FG++ RVW+ ++L++ DA+ E +L+S H+ K Y+ WLG GLL+S G Sbjct: 19 YVLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGK 78 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILL 141 W RK+I PTFH +IL+ FV +F+Q SN V++L + G TFDV+ + +DI+ Sbjct: 79 VWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSICAAALDIIA 138 Query: 142 ETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGII 201 ETAMG Q YA AV + ++ R +++ E++F Sbjct: 139 ETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFT--------------- 183 Query: 202 HGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDF 261 LT+ +K ++ + T++EFT +++ + L D K +D Sbjct: 184 --LTHPHLKWRQTQLIR---------TMQEFTI---KVIEKRRQALEDQQSKL----MDT 225 Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321 DE DVG K+R+A LD+++ S+ +G +++ EI+EEVDT MFEGHDTT + SF L L Sbjct: 226 ADE-DVGSKRRMALLDVLLMSTVDG-RPLTNDEIREEVDTFMFEGHDTTTSALSFCLHEL 283 Query: 322 GIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380 H +VQA++ +E+ Q+ G D RP + D E+KY+E VI ESLR+YPPVP++ RKL Sbjct: 284 SRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQT 343 Query: 381 DVTISTKNY---VIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIP 437 D + + VIPAG+ ++IG F +HRQP+ + +P+ F P+ EN + IP Sbjct: 344 DFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERH--ENGSRVAPFKMIP 401 Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 FSAGPR+C+G+K+A R + + E + +I+L+ GFQ+ + Sbjct: 402 FSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIV--NIVLRSETGFQLGMRK 459 Query: 498 RK 499 RK Sbjct: 460 RK 461 >UniRef50_Q170T0 Cluster: Cytochrome P450; n=12; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 505 Score = 277 bits (679), Expect = 5e-73 Identities = 165/477 (34%), Positives = 259/477 (54%), Gaps = 43/477 (9%) Query: 28 GNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSH 87 G R+W+G LI + DA +E IL+S +DK+ +Y F +PWLG GLL S+G KW S Sbjct: 68 GKFYRLWIGPDLIFPITDAKLVEAILSSQKLLDKSVQYDFIRPWLGNGLLTSTGRKWHSR 127 Query: 88 RKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLETAM 145 RK+I PTFH IL+ FV IF+Q SN V +LKS+ G+ FDV ++ +D++ E+AM Sbjct: 128 RKIITPTFHFKILEQFVEIFDQQSNIFVGQLKSKAQSGEDFDVFPVVTLCALDVICESAM 187 Query: 146 GISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205 G Q S Y AV M + R +K + R F T +F ++ Sbjct: 188 GTKVNAQLNSDSKYVRAVKDMATVAMARSFKAFAR----FNFTFYFTPYRRM----QDKA 239 Query: 206 NKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDEN 265 KV+ + ++ + ++ LE LA A T SD +EN Sbjct: 240 LKVLHDYTDSVIRSRR-------LE---------LAKGAFTKSD------------ENEN 271 Query: 266 DVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQ 325 DVG +K++AFLD++++++ +G + D E++EEVDT MFEGHDTT + SF++ +L H Sbjct: 272 DVGIRKKVAFLDMLLQATVDG-RPLDDLEVREEVDTFMFEGHDTTTSAISFLIGILAKHP 330 Query: 326 DVQARVYDELYQIFGDS-DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384 DVQ +VYDE+ + GD + T + ++ YL+ VI E+LRLYP VP+ R L + I Sbjct: 331 DVQQKVYDEVRNVIGDDLNVSVTLSMLNQLNYLDLVIKETLRLYPSVPIYGRMLLENQEI 390 Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPE-NTQNRHYYSYIPFSAGPR 443 + V PAG+ + I + + R P+Y+++P F P+ F E + + + Y Y+PFSAGPR Sbjct: 391 N--GTVFPAGSNLAIFPYFMGRDPEYFENPLEFRPERFAVETSAEKANPYRYVPFSAGPR 448 Query: 444 SCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500 +C+G+K+A R++ + ++ +++L+ G +++ R R Sbjct: 449 NCIGQKFAVAEIKSLISKLVRHYEVLPPKQPNSERMIAELVLRPEGGVPVRIRSRVR 505 >UniRef50_UPI0000D55ACE Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 501 Score = 275 bits (674), Expect = 2e-72 Identities = 160/480 (33%), Positives = 258/480 (53%), Gaps = 46/480 (9%) Query: 23 YAQTFGNVIRVWLGS-KLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSG 81 YA+ G ++ + G K + D +E +L+S+ + K+ RF +PW+G GL+ + G Sbjct: 64 YAKAHGTMVHLKFGPFKHALLCTDTKFLEFLLSSNKLLKKSVNLRFLEPWIGTGLVTADG 123 Query: 82 -PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG-KTFDVHDYMSGTTVDI 139 PKW++HRK+I P FH IL+ FV IF + +V+KL G K+ D++ Y++ T+DI Sbjct: 124 GPKWKTHRKLITPAFHFKILEQFVDIFESGGDILVKKLSEVSGSKSCDIYPYITKCTLDI 183 Query: 140 LLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLG 199 + ETAMG Q+ Y ++ +MC I F +R+ F F Sbjct: 184 ICETAMGTKVDVQNTENSAYFESIKEMCRI-------FTVRTVGAFLSNDF--------- 227 Query: 200 IIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDL 259 + + K+ ++ KA ++ +HS E++ N K L + +++ Sbjct: 228 --------IFRFSKDYKIQTKAVKVLH-------NHSNEVIVNKRKELKE------KNNE 266 Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319 + +D +++G KK+ FLDL++ ++ +G + +S EI+EEVDT MF GHDTT +SF+L Sbjct: 267 NTSDIDELGRKKKKVFLDLILSATTDGQS-LSPEEIREEVDTFMFGGHDTTGTATSFILY 325 Query: 320 LLGIHQDVQARVYDELYQIFGDSDRP-ATFADTLEMKYLERVILESLRLYPPVPVIARKL 378 + +++ Q ++ +E Q+FGD P T++ EMKYLE I E LRLY PVP+ R + Sbjct: 326 CIANNKEAQEKILEEQKQLFGDERSPKVTYSTLQEMKYLENAIKEGLRLYSPVPIYGRLI 385 Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPF 438 ++D + +IP G V+I +H PKYY +PE F+P F ENT + +++IPF Sbjct: 386 DQDTEYN--GTMIPKGVGVIIFAHGIHMNPKYYPNPEKFDPSRF--ENTTGKDPFTFIPF 441 Query: 439 SAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 SAGPR+C+G+KYA RNF P E L + +LK G ++ ++ R Sbjct: 442 SAGPRNCIGQKYAMLEIKSLVSKVVRNFELFPASPTHEMHLAPETVLKSLNGVKIGLKMR 501 >UniRef50_UPI00015B604A Cluster: PREDICTED: similar to cytochrome P450 CYP4AB2; n=8; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis Length = 519 Score = 272 bits (666), Expect = 2e-71 Identities = 158/480 (32%), Positives = 255/480 (53%), Gaps = 36/480 (7%) Query: 14 QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLG 73 +K N+ + + + + WLG V + DD+EI+L+S H++K + Y PWL Sbjct: 59 KKTWNVIRDLNKNYYPIAKFWLGPYPYVSIHHPDDLEILLSSTKHLEKGSAYTVLHPWLR 118 Query: 74 EGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFD-VHDYM 132 GLL SSG KW+ RK++ P FH IL+ ++ I N++ +E L++E +T + + Sbjct: 119 TGLLTSSGSKWQQRRKILTPAFHFKILRKYMDITNEHGKKFIEALRTENSETVQSLMPFC 178 Query: 133 SGTTVDILLETAMGISR-KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFF 191 S T+ I+ ETAMGI+ K + +Y AV + ++I R + +++ ++ + +F Sbjct: 179 SNYTLHIICETAMGIALDKIDTKISKEYKNAVADIANLIMYRVMRPYLKEWMMLPVWTF- 237 Query: 192 KQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTV 251 G + T + + +T L + + +H K + Sbjct: 238 -------GRLQTQTLRTLHKFTKTVLTERRE-----------YH---------KRSDNKY 270 Query: 252 FKGYRDDL-DFN-DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDT 309 KG+ DD D N D+ +G KK+LA LDL++ ++Q+G D IKEEVDT MF GHDT Sbjct: 271 LKGFHDDTYDVNKDDVAIGGKKKLAMLDLLLSAAQDGLT--DDEGIKEEVDTFMFAGHDT 328 Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYP 369 T + + LL H+++Q + E+ ++ +S+ + ++ YLER I ESLR++P Sbjct: 329 TGIALVYAIMLLAEHKEIQEKARAEVIEVLTESNGEIGTLEIQKLHYLERCIKESLRIFP 388 Query: 370 PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQN 429 PV ++R + D+ + KNYV+PAGT + F LHR P ++ +PE ++PD FLPEN Q Sbjct: 389 PVSALSRTVKEDIQL--KNYVVPAGTEIGCHIFDLHRDPNFWPEPEKYDPDRFLPENIQG 446 Query: 430 RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAE 489 RH Y+YIPFSAG R+C+G+K+A NF K+ KL D++ + E Sbjct: 447 RHPYAYIPFSAGSRNCIGQKFAMMELKSLTARILYNFELEPVSQTKDMKLTLDLVTRPLE 506 >UniRef50_A7SWY9 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 509 Score = 272 bits (666), Expect = 2e-71 Identities = 161/484 (33%), Positives = 261/484 (53%), Gaps = 42/484 (8%) Query: 21 LGYAQTFGNVIRVWLG-SKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLIS 79 +G+ F + +WL +K + + + +E+IL+S HI KA Y F PWLG GLL S Sbjct: 62 MGWCSQFKGIFCLWLSFAKPFLLIYEPKTVEVILSSSKHITKAQFYDFLLPWLGTGLLTS 121 Query: 80 SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG-KTFDVHDYMSGTTVD 138 +G KW+ R++I PTFH IL FV +F+Q S +V +KS+ K F++ ++ +D Sbjct: 122 TGEKWKKRRRLITPTFHFKILNDFVQVFDQQSQLMVSIIKSQPSDKVFNIFPLIACCALD 181 Query: 139 ILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLL 198 I+ +TAMG++ Q S +Y V++M ++I R + W+ ++ LT+ ++ Sbjct: 182 IIGKTAMGVNINAQKNSSSEYVKGVIRMSELIQSRQKRPWVHPAFLYCLTNEGREH---- 237 Query: 199 GIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDD 258 NK+IK +L + +I ++E + E +D+ Sbjct: 238 -------NKIIK-----FLHDFTNQVITERIQERLYSPKE-----------------QDE 268 Query: 259 LDFNDENDVGEKKRL-AFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFV 317 + +DE K+RL AFLD+++ + G +I ++EEVD MFEGHDTTAA ++ Sbjct: 269 TEESDEFTGRRKRRLVAFLDMLLNAYDAG--EIDVEGVREEVDIFMFEGHDTTAAAMAWA 326 Query: 318 LCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLE-MKYLERVILESLRLYPPVPVIAR 376 + LLG H DVQ + E+ + F + T AD+L+ +KYLE VI E+LR++P VP R Sbjct: 327 VQLLGEHPDVQRKAQAEVDEFFATNSGKLT-ADSLKGLKYLECVIKETLRIFPSVPFFGR 385 Query: 377 KLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYI 436 L D+ + + +IP GT V + T LHR P+ + P FNPD FLPEN++ RH Y+++ Sbjct: 386 SLVEDLELEGR--LIPKGTDVGVITIGLHRNPEVWPSPMKFNPDRFLPENSEGRHPYAFV 443 Query: 437 PFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496 PFSAG R+C+G+++A NF +S + K ++I + +G + + Sbjct: 444 PFSAGSRNCIGQRFALLEEKVVLAYILHNFDIVSTEKSTKIKTCAELITRPRDGIFVSLT 503 Query: 497 PRKR 500 R++ Sbjct: 504 TREQ 507 >UniRef50_Q9Y1T8 Cluster: Cytochrome P450 4W1; n=3; Arthropoda|Rep: Cytochrome P450 4W1 - Boophilus microplus (Cattle tick) Length = 549 Score = 256 bits (627), Expect = 1e-66 Identities = 150/495 (30%), Positives = 252/495 (50%), Gaps = 41/495 (8%) Query: 11 NLTQKLVNLALGYAQTFGN--VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFF 68 +++ L +A G+++ + N + R + + ++ L A+ +E +L S+ + K EY Sbjct: 83 DISTHLFQVAFGFSRIYKNHGMFRFYDATHPVLVLFKAEAVEELLTSNTVLKKGHEYELI 142 Query: 69 KPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TF 126 KPWLG GLL SSG KWRS RK++ P FH IL+ F+ N SN +V KL ++GK + Sbjct: 143 KPWLGTGLLTSSGSKWRSRRKLLTPAFHFRILEDFLPAVNDQSNILVRKL-GQLGKDRSC 201 Query: 127 DVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYK--FWMRSEIV 184 ++ ++ +DI+ ET MG + Q +Y A+ + +R +W+ + + Sbjct: 202 NIVPLVTLCALDIICETIMGYTINAQSNQDSEYVQAIKVLGHSFTRRLETPLYWI--DAI 259 Query: 185 FKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNA 244 F+L+ ++ + + +H T KVI+ E K + + P L+E Sbjct: 260 FQLSKPGREFARKVKELHQFTLKVIR-------ERKREILSCPELQE------------- 299 Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMF 304 Y + +D + R FLD+++ ++ ++EEVDT MF Sbjct: 300 ---------SYEETASESDVYGLKGTARKPFLDILLREHIKDPENFTEEHVREEVDTFMF 350 Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILE 363 EGHDTTA G S+ + L+ +H + Q ++ EL IFG D RP T D +MKY+E + E Sbjct: 351 EGHDTTAMGMSWAIYLIALHTEHQDLIHQELDTIFGSDKTRPVTSEDLKQMKYMECCLKE 410 Query: 364 SLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFL 423 S RLYP VP I+RK D I + +P GT + + + LH + + P+ F PD F Sbjct: 411 SQRLYPSVPFISRKCEEDAVICGRK--VPKGTDIQVAIYNLHHDEQVFPKPDEFRPDRFF 468 Query: 424 PENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDI 483 PEN + RH ++++PFSAGPR+C+G+++A RN++ ++ + + ++ Sbjct: 469 PENVRGRHAFAFVPFSAGPRNCIGQRFAMMEEKVVIANILRNYKLVALHYRDKIHVMAEL 528 Query: 484 ILKRAEGFQMKVEPR 498 +L+ G + PR Sbjct: 529 VLRPTSGLHVIFIPR 543 >UniRef50_Q9NB96 Cluster: P450 CYP319A1; n=2; Parasitiformes|Rep: P450 CYP319A1 - Boophilus microplus (Cattle tick) Length = 531 Score = 255 bits (625), Expect = 2e-66 Identities = 151/470 (32%), Positives = 242/470 (51%), Gaps = 32/470 (6%) Query: 34 WLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAP 93 +LG++ + + A+ +E+ LN+ K+ Y WL GLL S+GPKW+S R+M+ P Sbjct: 89 YLGTRPCITIYKAEHVEVFLNNRHTQSKSIHYELLHSWLRTGLLTSAGPKWKSRRRMLTP 148 Query: 94 TFHINILKSFVGIFNQNSNNVVEKLKSEVGKTF-DVHDYMSGTTVDILLETAMGISRKTQ 152 FH IL+ FV N+ + ++ + + + DV + +D+LLET MG++ Sbjct: 149 AFHFKILEDFVAPMNKMARLTAARITDRIKEPWIDVVPMAAACALDVLLETIMGVTNTND 208 Query: 153 DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNK 212 Y V + + + +R W+ + ++ T +Q K + IH T KVI + Sbjct: 209 GGESQRYVKNVNSVAERMVRRSQAPWLVLDCLYYRTEDGRQYQKNVSAIHAFTTKVISKR 268 Query: 213 KETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKR 272 +E + EI A N+K D K D DF+ KR Sbjct: 269 REEIIN-------------------EIHAANSK--KDNTPKM---DEDFHLTGRTF--KR 302 Query: 273 LAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVY 332 L F+D+++ S + ++ +I+EEVDT MFEGHDTTA G ++ L ++ H VQA+++ Sbjct: 303 LTFIDILLRYSIEVDSTLTTDDIREEVDTFMFEGHDTTAMGIAWSLYMIASHHHVQAKIH 362 Query: 333 DELYQIF-GDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVI 391 EL + D D T E+KY +RV+ E RL+P VPVI R + D+++ +V+ Sbjct: 363 KELDSVLQSDLDADITLEKIKELKYFDRVLKECQRLFPSVPVIGRATSEDISLG--KHVV 420 Query: 392 PAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 PA + V I + LHR + DPEVF+PD FLPEN + Y+Y+PFSAGPR+C+G++YA Sbjct: 421 PADSDVDIFIYALHRDQVCFPDPEVFDPDRFLPENVVHPAPYAYVPFSAGPRNCIGQRYA 480 Query: 452 XXXXXXXXXXXXRNFRTISEIPEK-EFKLQGDIILKRAEGFQMKVEPRKR 500 R F T+ + ++ + L +++L+ G ++ PR R Sbjct: 481 LMEVKIIVATILRRF-TLEAVDQRDQLMLACELVLRPLNGLKVSFTPRSR 529 >UniRef50_Q9N574 Cluster: Cytochrome p450 family protein 31A3; n=4; Nematoda|Rep: Cytochrome p450 family protein 31A3 - Caenorhabditis elegans Length = 511 Score = 254 bits (621), Expect = 5e-66 Identities = 161/484 (33%), Positives = 251/484 (51%), Gaps = 36/484 (7%) Query: 19 LALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLI 78 + +GY + +W+G + L AD +E I +S H++K Y +PWLG +L Sbjct: 60 IGMGYLYPDPRMCLLWIGPFPCLMLYSADLVEPIFSSTKHLNKGFAYVLLEPWLGISILT 119 Query: 79 SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTV 137 S +WR RK++ PTFH +ILK F+ IFN+ S +V+K+ S + DV ++ T+ Sbjct: 120 SQKEQWRPKRKLLTPTFHYDILKDFLPIFNEQSKILVQKMCSLGAEEEVDVLSVITLCTL 179 Query: 138 DILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKL 197 DI+ ET+MG + Q +Y AV + KL S K+ Sbjct: 180 DIICETSMGKAIGAQLAENNEYVWAV------------------HTINKLIS--KRTNNP 219 Query: 198 LGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRD 257 L + N I N ++++ K I+ F G + L D K + Sbjct: 220 L-----MWNSFIYNLYDSFIIKKVNSIL-----FFRTEDGRTHEKCLRILHDFTKKVIVE 269 Query: 258 DLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFV 317 + END + RLAFLDL++E ++G ++ + +++ EVDT MFEGHDTT+ G + Sbjct: 270 RKEALQENDYKMEGRLAFLDLLLEMVKSG--QMDETDVQAEVDTFMFEGHDTTSTGLMWA 327 Query: 318 LCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARK 377 + LLG H +VQ +V EL ++ GD D T MKYLE + E+LRL+P VP+I R+ Sbjct: 328 IHLLGNHPEVQRKVQAELDEVMGD-DEDVTIEHLSRMKYLECALKEALRLFPSVPIITRE 386 Query: 378 LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIP 437 L+ D I N IP G T ++ +++HR P +KDP+VF+PD FLPEN+ R +++IP Sbjct: 387 LSDDQVIGGVN--IPKGVTFLLNLYLVHRDPSQWKDPDVFDPDRFLPENSIARKSFAFIP 444 Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 FSAG R+C+G+++A RNF + E + + +II++ MK+ Sbjct: 445 FSAGSRNCIGQRFALMEEKVIMAHLLRNFNVKAVELMHEVRPKMEIIVRPVTPIHMKLTR 504 Query: 498 RKRV 501 R+ + Sbjct: 505 RRPI 508 >UniRef50_UPI00015B4DC8 Cluster: PREDICTED: similar to corpora allata cytochrome P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to corpora allata cytochrome P450 - Nasonia vitripennis Length = 513 Score = 248 bits (607), Expect = 3e-64 Identities = 150/478 (31%), Positives = 249/478 (52%), Gaps = 42/478 (8%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82 +AQ FG++ +W+G + VF+ + + +L+S HIDK+ EY + KPWLG GL+ S+G Sbjct: 75 WAQEFGDIYLLWVGLRPFVFVYRMEAVGTLLSSRQHIDKSLEYEYLKPWLGSGLITSTGE 134 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHDYMSGTTVDILL 141 +W + RK++ PTFH +LK + + + ++ VE L+SE+GK FD+ + +D + Sbjct: 135 RWLARRKLLTPTFHSELLKGYFRVTLREADTFVECLRSEIGKLEFDIVPFAKRAALDTIC 194 Query: 142 ETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGII 201 AMG Q +Y AV ++ I QR + + I+ K FK T LG Sbjct: 195 VCAMGHQLNAQVNRRNEYVQAVQRLT-AISQRRF-----TSILLKPELLFKVST--LGRE 246 Query: 202 HGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDF 261 H +VI E+ G+I T ++ G L A+ Sbjct: 247 HDRALRVI--------EDFVNGVITDTKRDWL---GSRL-RRARA--------------- 279 Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321 N+ + + LDL+++ QNG K++D+++++EV+T MF GHDT S++L L Sbjct: 280 -SNNNERKPRPETLLDLLLQMVQNG-EKLTDNDLRDEVNTFMFAGHDTVGMSVSWILYSL 337 Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381 G H + Q R+ E+ + ++ F + +L + E+ RLYP P+IAR++N Sbjct: 338 GRHPEYQERIIREVEDLLA-AEGELGFESYNRLHWLGACVKEAWRLYPVTPLIARQINSP 396 Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441 +T+ +N+ IP GTTV+I +++LHR P+Y+ +PE F P+ FLP +++IPFSAG Sbjct: 397 ITL--QNHDIPVGTTVLINSYLLHRDPRYFPEPERFKPERFLP-GASKPPSFAFIPFSAG 453 Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 R+C+G K+A R +R + + E + L ++L G Q+ + PR+ Sbjct: 454 SRNCIGYKFATIEVKVTVLALLRAYRFRAILREDQLHLLSQVVLDNVGGIQLSITPRQ 511 >UniRef50_Q4R1I7 Cluster: Cytochrome P450; n=1; Papilio xuthus|Rep: Cytochrome P450 - Papilio xuthus Length = 506 Score = 239 bits (584), Expect = 2e-61 Identities = 152/473 (32%), Positives = 242/473 (51%), Gaps = 43/473 (9%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 ++R WLG L +VD D+E+IL + ++K +RF + +G GL+ + WR RK Sbjct: 71 ILRGWLGHILYFIVVDPVDVEVILKTS--LEKDDLHRFIRNVIGNGLIFAPVSIWRRRRK 128 Query: 90 MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTF-DVHDYMSGTTVDILLETAMGIS 148 + P F I+ +F+ +F + S +V L + G + + Y+ T+D + ET MGI+ Sbjct: 129 ITVPAFSPKIVDTFMEVFAEQSEKLVSVLAACAGNGYIAMEPYLCRYTLDSVCETTMGIT 188 Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKV 208 Q+ Y A+ + +++ +R + W++ + ++K FF Q H K Sbjct: 189 TNAQNNPNAPYLKALKNILNLVCERIFHLWLQPDWLYK---FFSQSKS-----HQKYTKE 240 Query: 209 IKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVG 268 ++ + ++NK + I K L V D +F N Sbjct: 241 MQGFVDEVIQNKRREI-----------------KKEKDLKSEV------DRNFGLSN--- 274 Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328 K +FLDL+IE S G N +D E++EE+ T+ G DTT + L LL ++ VQ Sbjct: 275 -YKTQSFLDLLIEFS-GGENGYTDLELREEILTLTIAGTDTTGISIGYTLKLLAMYPKVQ 332 Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 ++Y EL +FG SDR D ++KYLER++ ESLRLYPP P I RK+ D+++ + Sbjct: 333 DKLYQELLDVFGTSDRRIVKEDLSKLKYLERIVKESLRLYPPGPFIIRKVLEDISLPS-G 391 Query: 389 YVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447 V PAG+ + + LHR PKY+ D EVF+PD FLPE +H SYIPFS+GPR+C+G Sbjct: 392 RVFPAGSGAAVSIWGLHRDPKYWGPDAEVFDPDRFLPERFNLKHACSYIPFSSGPRNCIG 451 Query: 448 RKYAXXXXXXXXXXXXRNFRTISEI--PEKEFKLQGDIILKRAEGFQMKVEPR 498 +YA R ++ + E P K + DI++K + +++ +E R Sbjct: 452 YQYALMSMKTVLSAIVRRYKIMGEESGPVPHIKSKIDIMMKAVDDYKICLEKR 504 >UniRef50_O45120 Cluster: Family 4 cytochrome P450; n=2; Coptotermes acinaciformis|Rep: Family 4 cytochrome P450 - Coptotermes acinaciformis Length = 501 Score = 237 bits (581), Expect = 4e-61 Identities = 115/235 (48%), Positives = 157/235 (66%), Gaps = 3/235 (1%) Query: 264 ENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323 +N++G K+R AFLDLM+++SQ+G + ++D EI+EEVDT MFEGHDTT + SF + L Sbjct: 270 QNELGLKRRHAFLDLMLQASQDGAS-LTDEEIREEVDTFMFEGHDTTTSALSFTMWCLAK 328 Query: 324 HQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383 +QDVQ + EL QIFGDS R ATF D EMKYLE+VI E+LRLYP V R+L + T Sbjct: 329 YQDVQEKAVVELKQIFGDSTRDATFRDLQEMKYLEQVIKETLRLYPSVNCFGRQLTENFT 388 Query: 384 ISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443 + +YV PAG V I + LHR+P+Y+ DPE F+PD FLPEN RH Y Y+PFSAGPR Sbjct: 389 VG--DYVNPAGANVWIYPYHLHRRPEYFPDPERFDPDRFLPENCVGRHPYCYVPFSAGPR 446 Query: 444 SCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 +C+G+K+A R+F+ I + + D +L+ A G ++K++PR Sbjct: 447 NCIGQKFAILELKSTISQVLRSFKVIESDCNGNIRYKLDFVLRSASGLKVKLQPR 501 Score = 130 bits (314), Expect = 8e-29 Identities = 70/200 (35%), Positives = 108/200 (54%), Gaps = 1/200 (0%) Query: 19 LALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLI 78 L G G ++R+W G+ LIV L +A +E +L+S IDKA YRF PWLG GLL Sbjct: 59 LVEGLIYKHGTIVRLWSGAYLIVILTEAKYVEALLSSTSQIDKAYTYRFVWPWLGSGLLT 118 Query: 79 SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTV 137 S+G + + +F + + F G Q +VEK V G FDV YM+ + Sbjct: 119 STGQALGNPPQAADSSFPLQGTREFRGCVQQKWKILVEKFSRHVNGPEFDVTPYMTLCAL 178 Query: 138 DILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKL 197 D + ET+MG++ Q +S +Y A+ + +I+ R K W S+ F+L++ ++Q K Sbjct: 179 DNMSETSMGVTLNAQKDSDSEYVRAIHSLGEIVFTRSGKPWYHSDTTFRLSTLGREQQKN 238 Query: 198 LGIIHGLTNKVIKNKKETYL 217 L I+H T VI+++K+ L Sbjct: 239 LAILHSFTRSVIRSRKQELL 258 >UniRef50_Q170S9 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 497 Score = 234 bits (572), Expect = 5e-60 Identities = 157/476 (32%), Positives = 246/476 (51%), Gaps = 43/476 (9%) Query: 15 KLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGE 74 ++ L YAQ +G ++ + + D E ILN+ + K+ +Y W+G Sbjct: 52 EIFKLLRRYAQQYGTAYKLSFWYQYTLVFAKPDIAEKILNTQSYASKSEDYDKVAEWIGY 111 Query: 75 GLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSG 134 GLLIS G KW RK++ P FH IL+SFV +FN+ S+ + KL S G DV + Sbjct: 112 GLLISKGEKWFKRRKVLTPGFHFKILESFVRVFNEKSDVLCRKLASYGGSEVDVFPTLKL 171 Query: 135 TTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQ 194 T+D+L ETA+G S Q E F Y AV ++ I++ ++F+ V L F KQ Sbjct: 172 YTLDVLCETALGYSCNAQTEDSF-YPAAVEELMSILY---WRFFNLFASVDTLFRFTKQY 227 Query: 195 TKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKG 254 + +K+I + +E L+ I+ K L++ Sbjct: 228 RRF--------HKLIGDTREFTLK--------------------IIEEKRKLLNEL---- 255 Query: 255 YRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGS 314 D+ N+E+D G KK++A LDL++ ++ +G +SD +I+EEVDT F GHDTTA+ Sbjct: 256 -HDEGAVNEEDDEG-KKKMALLDLLLRATVDG-KPLSDDDIREEVDTFTFAGHDTTASAL 312 Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374 +F+L + + DVQ ++++E+ + G S + +++YL+ VI ESLRLYP VP+I Sbjct: 313 TFLLFNIAKYSDVQQKLFEEISSVVG-STSELSLHTLNDLRYLDLVIKESLRLYPSVPMI 371 Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRH-YY 433 AR + + + IP T V + F +HR P ++DPE F P+ F +H + Sbjct: 372 ARIATENTKLD--DMPIPKCTCVSVDIFQMHRDPDRFEDPESFIPERFDAIRDGGKHNAF 429 Query: 434 SYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAE 489 +YIPFSAG R+C+G+K+A + FR P+ E L+ +I+LK AE Sbjct: 430 TYIPFSAGNRNCIGQKFAQYELKIAVVKLIQTFRLELPSPDIEPILKAEIVLKPAE 485 >UniRef50_Q16ML8 Cluster: Cytochrome P450; n=3; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 509 Score = 232 bits (568), Expect = 1e-59 Identities = 115/240 (47%), Positives = 156/240 (65%), Gaps = 3/240 (1%) Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319 D ++ G KKRLAFLDL++E + +++D +++EEVDT MFEGHDTT AG S+ L Sbjct: 273 DTGEDLYFGTKKRLAFLDLLLEGNAKH-KQLTDDDVREEVDTFMFEGHDTTTAGMSWALF 331 Query: 320 LLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLN 379 LLG+H D Q RV+ E+ IF SDRPAT D EMK LER + E+LRLYP V RKL+ Sbjct: 332 LLGLHPDWQDRVHQEIDSIFAGSDRPATMKDLGEMKLLERCLKETLRLYPSVSFFGRKLS 391 Query: 380 RDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFS 439 DVT+ Y IPAGT + I + +HR ++Y DPE F+PD FLPENT++RH ++YIPFS Sbjct: 392 EDVTLG--QYHIPAGTLMGIHAYHVHRDERFYPDPEKFDPDRFLPENTEHRHPFAYIPFS 449 Query: 440 AGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 AGPR+C+G+K+A R FR S E K+ ++I + EG ++ +E R+ Sbjct: 450 AGPRNCIGQKFAILEEKSIVSSVLRKFRVRSANTRDEQKICQELITRPNEGIRLYLEKRQ 509 Score = 148 bits (358), Expect = 4e-34 Identities = 69/190 (36%), Positives = 109/190 (57%), Gaps = 2/190 (1%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86 + ++ R+W G + + + + +E I+ + H++K+ Y F WLGEGLL S G +W Sbjct: 71 YPDIHRIWTGMRPEIRISKPEYVETIIGASKHMEKSHGYDFLFDWLGEGLLTSKGERWFQ 130 Query: 87 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETA 144 HRK+I PTFH NIL F +F + + E+L+ + GK DV +++ +DI+ ETA Sbjct: 131 HRKLITPTFHFNILDGFCDVFAEQGAVLAERLEPFANTGKPVDVFPFITKAALDIICETA 190 Query: 145 MGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGL 204 MG+ Q +Y A+ +M +I R K W+ E +FK T + +Q K L I+HG Sbjct: 191 MGVKVNAQTGGENNYVNAIYRMSEIFVDRSIKPWLHPEFIFKRTEYGRQHKKALDIVHGY 250 Query: 205 TNKVIKNKKE 214 T KVI+++KE Sbjct: 251 TKKVIRDRKE 260 >UniRef50_UPI00015B5014 Cluster: PREDICTED: similar to cytochrome P450 CYP4AB2; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis Length = 604 Score = 229 bits (561), Expect = 1e-58 Identities = 141/472 (29%), Positives = 248/472 (52%), Gaps = 21/472 (4%) Query: 26 TFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWR 85 T+ + + W ++ + DD+E+IL+S K Y++ + WL +GLL + G +R Sbjct: 144 TWYPICKGWAMGLPLLSVRHPDDLEVILSSQKACYKEFPYKYLRSWLNDGLLTNKGDTYR 203 Query: 86 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTF--DVHDYMSGTTVDILLET 143 + R+M+ P FH N+L+ +V I N+ S ++ +L++ GK F DV + +++I++E+ Sbjct: 204 ARRRMLTPAFHFNMLRRYVDIMNEQSGRLMTELRAN-GKEFVLDVLPIYADVSLNIIIES 262 Query: 144 AMGISRKTQDESGF-DYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202 AMGI D+ DY A+ M ++ R + ++ ++ T ++Q L ++ Sbjct: 263 AMGIDLDKTDKKVIKDYKEAIEDMGIVLTYRMLRPYILDWMMTPFTEIGRKQIHALKVLR 322 Query: 203 GLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFN 262 T+K+IK +++ + GI +EFT + L N + S++++ + L + Sbjct: 323 EFTDKIIKERRKYH--EMLGGI--KGYKEFT----DSLENQDE--SESIY--VKIQLMIH 370 Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 G KK+L LD+++ + ++G + + IKEEVDT + G DTT ++ L+ Sbjct: 371 -HFFTGHKKKLPMLDILLSAEKDGL--LDEKGIKEEVDTFLLGGTDTTRMVMAYFTMLMA 427 Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382 ++ Q + E+ ++ S + +M YLE+ I ES+RLYP I R D+ Sbjct: 428 ENKKCQDKARAEVCKVLERSGGKRGMTELSQMPYLEQCIKESMRLYPIASTIFRHTVDDI 487 Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442 + KNY IPAG V+ HR P ++ +PE F+PD FLPEN ++RH ++Y+PFSAGP Sbjct: 488 QL--KNYTIPAGVVVICQIIDAHRDPNFWTEPEKFDPDRFLPENCRHRHPFAYLPFSAGP 545 Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMK 494 R+C+G+K+ NF ++ +L GD +L+ A+ F K Sbjct: 546 RNCIGQKFGWMEVKAVCSRLLYNFYLEPIDSTRDMQLIGDFVLRPADPFHTK 597 >UniRef50_UPI00015B561A Cluster: PREDICTED: similar to cytochrome P450 CYP4AB2; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis Length = 478 Score = 221 bits (540), Expect = 3e-56 Identities = 131/436 (30%), Positives = 222/436 (50%), Gaps = 33/436 (7%) Query: 32 RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMI 91 R+W + +V D DD+ I+L +I K Y +F GL+ S+G KW+ RK++ Sbjct: 39 RIWFFTCAVVITQDPDDLRILLTDKTNITKGFVYEYFHLMAKTGLITSTGEKWQYRRKIL 98 Query: 92 APTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFD-VHDYMSGTTVDILLETAMGISRK 150 P FH +I+K ++ I + V+ +K++ +T + S T+ I+LE AMGI + Sbjct: 99 TPAFHTHIIKKYMKITFEQGERFVKSIKAQGDETVQSLIPVCSDLTLSIILEAAMGIQFQ 158 Query: 151 TQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIK 210 T +Y A+ I R + +++ ++ +F + ++L + KV++ Sbjct: 159 TIGNKAEEYRKAIEHYFSSIAYRATRPYIKDWML----RYFSEGRRILATV-----KVLR 209 Query: 211 NKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEK 270 + ++ + + +H +T ++ K DD++ + G K Sbjct: 210 EFTDKIIDERRE-----------YHK--------QTKQESFQKYVDDDMEHECTDGEGRK 250 Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330 KRLA LDL++ + + G I + IKEEVDT G+DTT ++L L+ ++D Q Sbjct: 251 KRLAMLDLLLMAEKEGL--IDEEGIKEEVDTFTAAGYDTTGMEMVYLLMLMAENKDQQEL 308 Query: 331 VYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYV 390 E +I S + + +M+Y+ER + ESLRL+P P I R + D+ + KNY+ Sbjct: 309 ARAEANRILDASGGKISMKEINQMEYIERCVKESLRLFPTAPHIVRAVTEDIQL--KNYM 366 Query: 391 IPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKY 450 +PAGT + + +LHR PKY+ DP F+PD FLP + R+ ++Y+PFS GPR+C+G+K+ Sbjct: 367 VPAGTDIFVPIHILHRDPKYWSDPLKFDPDRFLPGEAEKRYPFTYLPFSHGPRNCIGQKF 426 Query: 451 AXXXXXXXXXXXXRNF 466 A RNF Sbjct: 427 AIAELKSLLACVLRNF 442 >UniRef50_A0JMQ6 Cluster: Cytochrome P450, family 4, subfamily V, polypeptide 2; n=9; Coelomata|Rep: Cytochrome P450, family 4, subfamily V, polypeptide 2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 513 Score = 215 bits (525), Expect = 2e-54 Identities = 99/245 (40%), Positives = 155/245 (63%), Gaps = 2/245 (0%) Query: 255 YRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGS 314 Y ++ + E+D G +KR AFLD+++++ ++ +I+EEVDT MFEGHDTTAA Sbjct: 267 YLSYVESDSESDQGMRKRRAFLDMLLKTKDEDGKMLTHKDIQEEVDTFMFEGHDTTAAAM 326 Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374 ++ + LLG H +VQ + EL+++FG+S+RP D +++YLE VI ESLRL+P VP Sbjct: 327 NWAIHLLGSHPEVQRKAQQELFEVFGESERPVNTEDLKKLRYLECVIKESLRLFPSVPFF 386 Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434 AR + D I+ + +P GT +V+ T+ LHR P+++ DPE F P+ FLPEN RH Y+ Sbjct: 387 ARTICDDTQIN--GFKVPKGTNIVVITYALHRDPRFFPDPEEFRPERFLPENCVGRHPYA 444 Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMK 494 YIPFSAG R+C+G+++A R F ++ +E + G+++L+ +G + Sbjct: 445 YIPFSAGLRNCIGQRFAIMEEKVILAYILRYFNIVACQKREELRPLGELVLRPEQGIWIT 504 Query: 495 VEPRK 499 +E RK Sbjct: 505 LERRK 509 Score = 149 bits (362), Expect = 1e-34 Identities = 74/207 (35%), Positives = 118/207 (57%), Gaps = 5/207 (2%) Query: 21 LGYAQTFGN--VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLI 78 +GY F N ++++W+G + L A+ +E +LN+ VHIDKA Y+F PWLG GLL Sbjct: 70 VGYTTEFQNSPLLKIWIGPIPFLILFHAETVETVLNNPVHIDKAYAYQFLHPWLGTGLLT 129 Query: 79 SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTV 137 S+G KWR RKM+ PTFH +IL F+ + N+ + ++EKL+ + GK F+ +++ + Sbjct: 130 STGDKWRRRRKMLTPTFHFSILTEFLEVMNEQAEVLIEKLEKQAGKGPFNCFSHITLCAL 189 Query: 138 DILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKL 197 DI+ ETAMG Q +Y V +M DII +R W + V+ ++ + Sbjct: 190 DIICETAMGKRIYAQSNYDSEYVRTVYRMSDIITRRQRMPWYWPDFVYNYVGEGREHNRS 249 Query: 198 LGIIHGLTNKVIKNKKE--TYLENKAK 222 L I+H T VI + E +Y+E+ ++ Sbjct: 250 LKILHSFTESVINERAEYLSYVESDSE 276 >UniRef50_Q6ZWL3 Cluster: Cytochrome P450 4V2; n=83; Coelomata|Rep: Cytochrome P450 4V2 - Homo sapiens (Human) Length = 525 Score = 214 bits (522), Expect = 5e-54 Identities = 103/230 (44%), Positives = 149/230 (64%), Gaps = 2/230 (0%) Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328 + KR AFLDL++ + + N++S +I+EEVDT MFEGHDTTAA ++ L LLG + +VQ Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352 Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 +V EL +FG SDRPAT D +++YLE VI E+LRL+P VP+ AR ++ D ++ Sbjct: 353 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 410 Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 Y + GT VI + LHR P+Y+ +PE F P+ F PEN Q RH Y+Y+PFSAGPR+C+G+ Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 470 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 K+A R+F S +E L+G +IL+ + G +K++ R Sbjct: 471 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRR 520 Score = 140 bits (338), Expect = 1e-31 Identities = 68/184 (36%), Positives = 113/184 (61%), Gaps = 1/184 (0%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 ++++W+G +V L +A+++E+IL S IDK++ Y+F +PWLG GLL S+G KWRS RK Sbjct: 89 LLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRK 148 Query: 90 MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG-KTFDVHDYMSGTTVDILLETAMGIS 148 M+ PTFH IL+ F+ I N+ +N +V+KL+ + + F+ Y++ +DI+ ETAMG + Sbjct: 149 MLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKN 208 Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKV 208 Q +Y AV +M ++I +R W+ ++ + + + K L I+H TN V Sbjct: 209 IGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKILHTFTNSV 268 Query: 209 IKNK 212 I + Sbjct: 269 IAER 272 >UniRef50_UPI0000D566B3 Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 511 Score = 212 bits (518), Expect = 2e-53 Identities = 104/247 (42%), Positives = 154/247 (62%), Gaps = 2/247 (0%) Query: 256 RDDLDFNDEND--VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAG 313 RD + E D +G+KKRLAFLDL++E+++N ++D +I+EEVDT MF GHDT+ Sbjct: 265 RDVVQELSEEDKLLGKKKRLAFLDLLLEANKNSEGGLTDEDIREEVDTFMFAGHDTSTVT 324 Query: 314 SSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPV 373 + L L + + Q +V+ EL +IF +RP T D L+M+YL++VI E+ RL P VPV Sbjct: 325 VGWTLFTLSNYPEYQEKVHQELDEIFQGEERPITPQDVLKMQYLDKVIKETQRLIPVVPV 384 Query: 374 IARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYY 433 IAR L++D+ I + IPAG VVI LH+ P + +P+ F+P+ FLPEN RH Y Sbjct: 385 IARTLDQDLEIVASSRTIPAGVMVVIHLARLHKDPDQFPEPDRFDPERFLPENVSKRHPY 444 Query: 434 SYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQM 493 S++PFSAGPR+C+G+K+A R ++ +E E K +I+L+ G + Sbjct: 445 SFVPFSAGPRNCLGQKFALRNTKVLLASILRKYKVRAEKKIDEMKYNIEIVLRPQGGLSV 504 Query: 494 KVEPRKR 500 +EPR+R Sbjct: 505 ALEPRRR 511 Score = 138 bits (334), Expect = 3e-31 Identities = 69/190 (36%), Positives = 110/190 (57%), Gaps = 2/190 (1%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSG-PKWR 85 +G R W+G V ++ D +E IL+S V++ K YRF PWLGEGL+ S KWR Sbjct: 70 YGPFFRTWMGFIPAVHVMKPDHVERILSSTVNLTKGDNYRFVVPWLGEGLITGSNHKKWR 129 Query: 86 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILLETA 144 HRK+I PTFH +IL + + + + + E+L + G+ F+++ +++ +DI+ ETA Sbjct: 130 VHRKLITPTFHFSILDNMMEVMAEKGQFLAEQLVPKANGQFFNIYPFLTLCELDIICETA 189 Query: 145 MGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGL 204 MG+ S +Y +V + DI+ R + ++ + VF L+S +Q K L I+HG Sbjct: 190 MGVEVNAMKHSQSEYVRSVYGISDIMLYRMFHPYLHPDFVFNLSSKGRQHKKYLSILHGF 249 Query: 205 TNKVIKNKKE 214 T KVI+ +KE Sbjct: 250 TRKVIQERKE 259 >UniRef50_UPI00015B569D Cluster: PREDICTED: similar to cytochrome P450 CYP4C39; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4C39 - Nasonia vitripennis Length = 510 Score = 210 bits (513), Expect = 7e-53 Identities = 103/229 (44%), Positives = 146/229 (63%), Gaps = 4/229 (1%) Query: 260 DFNDENDVGEKKR-LAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318 D + E++ G K+R AFLDL++E+S+N N +S+ E++ EVDT MF GHDTTA SF L Sbjct: 271 DEDKEDEFGIKQRNKAFLDLLLEASENDKNPLSNDELRNEVDTFMFAGHDTTATAISFTL 330 Query: 319 CLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARK 377 LLG H D+Q +V++EL +F D D+P AD ++KYL+RVI E+LRLYP P R Sbjct: 331 LLLGNHLDIQKKVHEELQTVFNNDVDKPTRAADLSQLKYLDRVIKETLRLYPSAPSFLRT 390 Query: 378 LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIP 437 L D + I G+ ++I + +HR PK +++P VF+PD FLPEN ++RH Y+YIP Sbjct: 391 LVEDTIFD--GHTICKGSVIIINAYDMHRDPKVWENPTVFDPDRFLPENVRSRHPYAYIP 448 Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486 FSAGPR+C+G+K+A R +R S+ + KL IIL+ Sbjct: 449 FSAGPRNCIGQKFAMLELKIALTAILRKWRVKSDTLPENLKLLHSIILR 497 Score = 116 bits (280), Expect = 1e-24 Identities = 59/189 (31%), Positives = 101/189 (53%), Gaps = 4/189 (2%) Query: 28 GNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSH 87 GNV +WLG + V + +E++L S V+I K++ Y PWLG+GLL +G KW H Sbjct: 71 GNVYIMWLGMQPYVNIQKPHHMEVLLTSTVNIKKSSIYNIIIPWLGDGLLTLTGKKWHHH 130 Query: 88 RKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG----KTFDVHDYMSGTTVDILLET 143 R+++ P FH +L+ F ++ ++ E LK +V + D+ + S T+D++ +T Sbjct: 131 RRLLTPAFHFRVLEQFTETMHEKADVFNECLKEQVSSNPKEPVDIFSFASRFTLDVICKT 190 Query: 144 AMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHG 203 AMGI Q S Y +V +M + R+ + W S+ ++ T KQ + ++ Sbjct: 191 AMGIDMDAQRGSMNLYTKSVNQMSRFVVNRYLRPWYASDFIYSKTEDGKQSQAAISVMRE 250 Query: 204 LTNKVIKNK 212 ++KVIK + Sbjct: 251 YSSKVIKER 259 >UniRef50_Q964T1 Cluster: Cytochrome P450 4c21; n=1; Blattella germanica|Rep: Cytochrome P450 4c21 - Blattella germanica (German cockroach) Length = 501 Score = 203 bits (495), Expect = 1e-50 Identities = 101/239 (42%), Positives = 151/239 (63%), Gaps = 7/239 (2%) Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321 +++ D+G+KKR+ FLD ++++S++ NK++D +I EEV T MFEGHDT +A +++L L Sbjct: 267 SEDADIGKKKRVPFLDTLLDASEDD-NKLTDTDILEEVHTFMFEGHDTVSAAMTWLLFEL 325 Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381 G H ++Q Y E+ IF SDR T AD M YLERVI ESLRL+P V R+ ++D Sbjct: 326 GHHPEIQEEAYKEVQDIFQGSDRVPTMADLNNMNYLERVIKESLRLHPSVIYFVREAHQD 385 Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441 + Y IPAGT + +HR P+ + +P FNPDNFLP+ NRH Y+YIPFSAG Sbjct: 386 FELG--GYTIPAGTNIDFSVPFIHRNPEIFPNPRCFNPDNFLPDRVVNRHPYAYIPFSAG 443 Query: 442 PRSCVGRKYAXXXXXXXXXXXXRN--FRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 PR+C+G+++A R+ FRT+++ + +FKL ++I + Q+ +E R Sbjct: 444 PRNCIGQRFALLEEKVVLSYLLRHYRFRTVNKREDSKFKL--EMINTPVKPIQLIIEAR 500 Score = 153 bits (371), Expect = 1e-35 Identities = 76/188 (40%), Positives = 112/188 (59%), Gaps = 1/188 (0%) Query: 34 WLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAP 93 + G++ V + + IE++L + IDKA Y F WLG GLL SSG KW HRK+I P Sbjct: 75 YFGNRPFVNISSPELIEVVLRNTQLIDKAFLYDLFHSWLGTGLLTSSGAKWHQHRKIITP 134 Query: 94 TFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRKTQ 152 TFH +IL+ F+ IF + S +V KL+ EVG+ F + Y+S +DI+ ETAMG S Q Sbjct: 135 TFHFSILEGFITIFAEKSEILVRKLQKEVGRGPFFIRQYVSNCALDIICETAMGTSVNAQ 194 Query: 153 DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNK 212 DE +Y A+ KM D++ R + E +FKLT ++ K L +++G NK+I+ + Sbjct: 195 DEGFSEYVTAINKMTDVLSDRMANPLLYPEFIFKLTPYYWTHKKCLKVLNGFVNKIIQER 254 Query: 213 KETYLENK 220 KE ++K Sbjct: 255 KEERKKSK 262 >UniRef50_Q7YSZ3 Cluster: P450 enzyme precursor; n=1; Rhodnius prolixus|Rep: P450 enzyme precursor - Rhodnius prolixus (Triatomid bug) Length = 512 Score = 202 bits (493), Expect = 2e-50 Identities = 106/270 (39%), Positives = 161/270 (59%), Gaps = 7/270 (2%) Query: 231 EFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKI 290 ++ H+ E + N K L + K Y ++ + ++N+ G+ K+ AFL+++I+ + Sbjct: 247 KYLHNFSENIIQNRK-LKYLLEKKYSEN-NIEEDNNFGKGKK-AFLNILIDLEDKSKGTL 303 Query: 291 SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFAD 350 +D +I+EEVD MF GHDTTA+ F L LLG H VQ + ++ELY+IFG+SDR D Sbjct: 304 TDKDIREEVDNFMFAGHDTTASCIMFTLYLLGRHPHVQEKAFEELYEIFGESDREVNNKD 363 Query: 351 TLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKY 410 M YLE +I ES+R+YPP P +R L +D+ + K V+P G V I F++HR PKY Sbjct: 364 LHGMHYLEMIIKESIRIYPPAPYFSRNLIQDLVLKDKT-VLPEGANVGIFAFIMHRDPKY 422 Query: 411 YKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTIS 470 + +PEVF+P+ F EN + RH Y+Y+PFSAGPR+C+G+K+A R F I Sbjct: 423 FPNPEVFDPERFSAENCKKRHPYAYLPFSAGPRNCIGQKFAMMELKVVLSTILR-FAKIE 481 Query: 471 EIPEK--EFKLQGDIILKRAEGFQMKVEPR 498 + ++ L I+LK + ++KV R Sbjct: 482 SVNDEISARSLTPLILLKPCDPIRIKVFSR 511 Score = 123 bits (297), Expect = 1e-26 Identities = 62/197 (31%), Positives = 105/197 (53%), Gaps = 1/197 (0%) Query: 25 QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKW 84 Q + ++ WL V+L D DD+E+IL S I K EY PW+ +GL++S G KW Sbjct: 72 QEYARLVAFWLAGIPTVWLFDPDDLEVILASSQAIQKGNEYHCLFPWMQDGLVLSKGEKW 131 Query: 85 RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETA 144 RK++ P FH IL++ + N+N+ ++ + + G+ F + + T+D++ ETA Sbjct: 132 HQRRKLLTPAFHFKILENNMQSLNKNARCLLRNMLKKEGRPFVTQELVVRCTLDVISETA 191 Query: 145 MGISRKTQD-ESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHG 203 MG + Q+ E DY AV + C + R + ++ V+ LT ++ +K L +H Sbjct: 192 MGHALNLQEREENNDYLNAVERACSLTFDRSKNVFYSNDGVYFLTLDGRKFSKNLKYLHN 251 Query: 204 LTNKVIKNKKETYLENK 220 + +I+N+K YL K Sbjct: 252 FSENIIQNRKLKYLLEK 268 >UniRef50_Q9VVN6 Cluster: Probable cytochrome P450 312a1; n=2; Sophophora|Rep: Probable cytochrome P450 312a1 - Drosophila melanogaster (Fruit fly) Length = 510 Score = 202 bits (493), Expect = 2e-50 Identities = 134/457 (29%), Positives = 227/457 (49%), Gaps = 40/457 (8%) Query: 32 RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMI 91 ++W+G+KL + + DI+ + ++ + K +YR F+ WL EGL S KW RK++ Sbjct: 75 KLWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFENWLCEGLFTSGFEKWSHRRKIV 134 Query: 92 APTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGISR 149 P F+ ++K FV +F + S ++ + +E G D +S T+D + ETA+G+S Sbjct: 135 MPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALGVSV 194 Query: 150 KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVI 209 +Q + +Y AV + II +R + R+ +FK TS +K++ +L I Sbjct: 195 GSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQEL-----------I 243 Query: 210 KNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGE 269 K L +GII ++E + N SD +LD G Sbjct: 244 KT-----LHGFTEGIIQKRIDEINQDA----ENRNYQSSDA-------ELD-------GV 280 Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329 K+ L FLD ++ S ++ +I+EEVDTI+F G D TA +F + + +H + Q Sbjct: 281 KRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQ 340 Query: 330 RVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 R +E++ + G D P + ++++LE I E+LR+YP P+ ARK + TI+ + Sbjct: 341 RCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTIN--D 398 Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 + IP G+ V+I + R ++ DP VF PD + ++IPF AG RSC+G+ Sbjct: 399 FFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFIPFMAGARSCMGQ 458 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIIL 485 +YA RNF + E++ KL+ + ++ Sbjct: 459 RYAMVMLKMVLAHLLRNF-LFEPLGERQVKLKLNFVI 494 >UniRef50_UPI0000E46807 Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily v; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily v - Strongylocentrotus purpuratus Length = 487 Score = 201 bits (491), Expect = 3e-50 Identities = 102/243 (41%), Positives = 152/243 (62%), Gaps = 5/243 (2%) Query: 259 LDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318 +D ND ND G K+R+AFLDL+++ ++ + + +I+EEVDT MFEGHDTTAA +S+ + Sbjct: 211 VDSND-ND-GSKRRIAFLDLLLKMQRDDPS-FTKSDIREEVDTFMFEGHDTTAALASWAM 267 Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKL 378 L+G H VQ +++ EL +FGDSDRP T D ++ YL V+ E+LR++P VP++ R L Sbjct: 268 FLIGHHTRVQKKLHQELDSVFGDSDRPVTADDLQKLPYLTCVLKETLRIFPSVPIVGRDL 327 Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPF 438 D I K + P GT ++I LHR P + +P +F+PD FLPE + RH +SY+PF Sbjct: 328 QEDCIIDGK--LAPRGTLLIIAIGSLHRDPTQFPEPLMFDPDRFLPEFSSKRHPFSYVPF 385 Query: 439 SAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 SAGPR+C+G+++A R F S K+ ++IL+ +EG MK+ R Sbjct: 386 SAGPRNCIGQRFALMEDKVLLANVLRCFSLESTQSLKDTMPIAELILRPSEGIHMKITRR 445 Query: 499 KRV 501 K + Sbjct: 446 KGI 448 Score = 97.9 bits (233), Expect = 6e-19 Identities = 55/145 (37%), Positives = 81/145 (55%), Gaps = 4/145 (2%) Query: 74 EGLL-ISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT--FDVHD 130 +GL+ + +G KW RKM+ PTFH IL +F+ +F++ SN + +K K ++ Sbjct: 73 KGLMRLCTGKKWFHRRKMLTPTFHFAILHNFIEVFDEQSNTLCQKFGEHAQKQDLVNICP 132 Query: 131 YMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSF 190 ++ +DI+ ETAMG QDES DY AVM+M DII QR K W + +F T Sbjct: 133 LVTLCVLDIISETAMGKQLHAQDESNNDYVNAVMRMSDIIQQRQKKPWFWPDPLFDNTKS 192 Query: 191 FKQQTKLLGIIHGLTN-KVIKNKKE 214 K+ + L I+H +TN KV N + Sbjct: 193 GKEHAQCLQILHKMTNTKVDSNDND 217 >UniRef50_Q9NGQ5 Cluster: Insecticide resistance-associated cytochrome P450; n=2; Cucujiformia|Rep: Insecticide resistance-associated cytochrome P450 - Diabrotica virgifera virgifera (western corn rootworm) Length = 501 Score = 196 bits (478), Expect = 1e-48 Identities = 91/230 (39%), Positives = 144/230 (62%), Gaps = 3/230 (1%) Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328 ++K+LAFLDL++ + + I D IK+EV+T MFEGHDTTA G S++L L H + Q Sbjct: 273 KRKKLAFLDLLLNAKLS-KGIIDDQGIKDEVNTFMFEGHDTTATGISWILRQLATHSEYQ 331 Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 ++Y+E+ + GD+ + D E+K +ER I E+LRL+PPVP IAR L+ D+ ++ Sbjct: 332 DQIYEEIITVLGDAQKQPDLNDLNELKVMERFIKETLRLFPPVPYIARTLDEDIELN--G 389 Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 Y+IP ++ I + +HR PK++ +PE F+PD FLPEN NRH ++Y+PFSAGPR+C+G+ Sbjct: 390 YLIPKEASIDIWIYDIHRNPKHWPEPEKFDPDRFLPENCVNRHPFAYVPFSAGPRNCIGQ 449 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 ++A +NF ++ ++ D++L+ A + PR Sbjct: 450 RFAMYEMKAIICGIMQNFSVKLADKNEKVEIMTDLVLRSAHEINLNFIPR 499 Score = 103 bits (247), Expect = 1e-20 Identities = 54/179 (30%), Positives = 95/179 (53%), Gaps = 2/179 (1%) Query: 40 IVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 99 +V + D+ E I + HI K Y +PWLG+GLL +SG W+ RK++ P FH +I Sbjct: 83 VVVVTGPDEFEKIASGSKHITKGMIYGLVEPWLGKGLLTNSGSLWQQRRKILTPAFHFSI 142 Query: 100 LKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHDYMSGTTVDILLETAMGISRKTQDESGFD 158 L+ FV +FN+ + +VE +K E K+ ++ +S T ++ + ET+ G + + + Sbjct: 143 LQEFVKVFNKETARLVETIKQENKKSATNIIPLISQTALNTIAETSFGTTLDLTKKDDKN 202 Query: 159 YAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTK-LLGIIHGLTNKVIKNKKETY 216 Y A+ +M I+ R + W S VF + S + K +L +H T ++I + + + Sbjct: 203 YVSAIHEMGKILIYRMVRPWFYSLFVFYILSSVGAKLKQVLSTLHSFTERIIPERSKDF 261 >UniRef50_A6Y7S1 Cluster: Female neotenic-specific protein 4; n=1; Cryptotermes secundus|Rep: Female neotenic-specific protein 4 - Cryptotermes secundus Length = 271 Score = 196 bits (477), Expect = 2e-48 Identities = 94/203 (46%), Positives = 126/203 (62%), Gaps = 3/203 (1%) Query: 265 NDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324 +D G + R+ LD++IE S+N + +++EE+ ++ ++TTA SF +L H Sbjct: 62 HDKGRRARIPILDMLIELSRNDKD-YGRLDVREEIAAMLIVSYETTAVALSFACWMLSQH 120 Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384 QDVQ +V E +IFGDSDRPAT+ D EMKYLE VI E++RLYP +PV RKL RD + Sbjct: 121 QDVQEKVLMEQKEIFGDSDRPATYRDIQEMKYLEMVIRETIRLYPSLPVFGRKLQRDFDV 180 Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRS 444 ++VIPAG V+ + +HR PKY+ DPE FNPD FLP+N R Y Y+ FSAGPR+ Sbjct: 181 G--DFVIPAGANVMFLAYQIHRNPKYFPDPEKFNPDRFLPDNVMRRSPYCYLAFSAGPRN 238 Query: 445 CVGRKYAXXXXXXXXXXXXRNFR 467 CVG KY R FR Sbjct: 239 CVGIKYGMQAIKGTLSAMIRKFR 261 >UniRef50_Q695H3 Cluster: Pheromone-degrading enzyme; n=2; Phyllopertha diversa|Rep: Pheromone-degrading enzyme - Phyllopertha diversa (Pale-brown chafer beetle) Length = 502 Score = 195 bits (476), Expect = 2e-48 Identities = 96/232 (41%), Positives = 144/232 (62%), Gaps = 4/232 (1%) Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327 G KK+ AFLDL++E S N + H I+EEVDT MFEGHDTTA +F L L ++ + Sbjct: 271 GRKKKQAFLDLLLEYSANDPSFTEQH-IQEEVDTFMFEGHDTTATSITFALYALAMNPHI 329 Query: 328 QARVYDELYQIFGD-SDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386 Q + Y EL +IF + S R A++ D EMKYLE VI E+LR+Y VP +R L DV ++ Sbjct: 330 QEKAYAELKEIFSNNSKRHASYRDLQEMKYLEMVIKETLRIYTTVPFYSRALEEDVNMNG 389 Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446 + ++P GT + + + +H PK YKDPE F+P+ F EN++ R +++IPFSAGPR+C+ Sbjct: 390 Q--ILPKGTMLNVFAYGVHHNPKIYKDPETFDPERFSIENSKERSPFAFIPFSAGPRNCI 447 Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 G+K+A RNF+ + +P + L+ + +LK G ++++ R Sbjct: 448 GQKFAMLEMKSSISDVLRNFKLLPSVPAHKVVLKSEAVLKSDNGVFVRLQKR 499 Score = 144 bits (349), Expect = 5e-33 Identities = 69/193 (35%), Positives = 118/193 (61%), Gaps = 2/193 (1%) Query: 28 GNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSH 87 GN ++++G++ VFLV+ D+E +LNS + K+ Y+F WLG GLL SSG KW+ H Sbjct: 68 GN-FKLYIGAQPRVFLVEPKDLEFLLNSTSLLTKSKSYKFLYRWLGAGLLTSSGNKWKKH 126 Query: 88 RKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMG 146 RK+I P FH IL+ F+ +FN S+ +VEKL + K + D++ +++ T+DI+ ETAMG Sbjct: 127 RKIITPAFHFQILEEFIDVFNSASDVLVEKLNAAPNKSSIDIYPFIARCTLDIICETAMG 186 Query: 147 ISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTN 206 S Q++ +Y +V + I+ QR + +++++ T+ ++++ L ++HG T Sbjct: 187 TSVDAQNDINSEYVNSVKILLGILVQRSLSPILANDLLYPFTTTYQKEKAALKVVHGYTK 246 Query: 207 KVIKNKKETYLEN 219 VI +K + N Sbjct: 247 SVINKRKIEFYNN 259 >UniRef50_O76478 Cluster: Corpora allata cytochrome P450; n=2; Neoptera|Rep: Corpora allata cytochrome P450 - Diploptera punctata (Pacific beetle cockroach) Length = 497 Score = 195 bits (476), Expect = 2e-48 Identities = 92/242 (38%), Positives = 152/242 (62%), Gaps = 4/242 (1%) Query: 258 DLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFV 317 +++ + +N + +K RLA LDL++E S+NG ++D +I EEVDT MF GHDT A+G S++ Sbjct: 258 EVEISQQNGIKKKHRLALLDLLLELSENG-KVLTDEDICEEVDTFMFAGHDTIASGVSWI 316 Query: 318 LCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIAR 376 L +LG H D Q ++ +E + D+ T ++ YLER I E++RLYP VP+IAR Sbjct: 317 LYVLGHHLDSQEKIVEEFKNVMEEDNTEWPTMKHLNKLCYLERCIKEAMRLYPVVPLIAR 376 Query: 377 KLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYI 436 L + + I +Y++P G T++I T++LHR +++ +P++F PD FL N + R+ ++Y+ Sbjct: 377 NLTQPIKIM--DYMLPEGVTILINTYLLHRDSRFFPNPDIFEPDRFLTSNCEARNPFAYV 434 Query: 437 PFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496 PFSAGPR+C+G+K+A + F S E+ KL G+++L +G ++ + Sbjct: 435 PFSAGPRNCIGQKFAMMELKIILSTVLQRFIVKSVDKEERLKLVGELVLLNRDGIRLTIT 494 Query: 497 PR 498 R Sbjct: 495 AR 496 Score = 155 bits (376), Expect = 3e-36 Identities = 76/195 (38%), Positives = 117/195 (60%), Gaps = 1/195 (0%) Query: 24 AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK 83 A +GN+ R+W+G + VFL A+ I+ ILNS V+IDK+ EY F PWLG GLL S+G K Sbjct: 58 ATKYGNIFRLWVGQRPFVFLYSAEAIQPILNSTVYIDKSYEYSFLFPWLGTGLLTSTGNK 117 Query: 84 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHDYMSGTTVDILLE 142 W + RK++ +FH +L+ F+ Q+S + +L+ E+ K F V Y +DI+ + Sbjct: 118 WHTRRKLLTQSFHSKVLEDFLEPIYQHSLFLCNRLELELDKPHFKVTPYAKLCALDIICD 177 Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202 TAMG + Q+ S +Y AV + +I+ +R W++ + +FK+T K+Q + L I+H Sbjct: 178 TAMGSTINAQENSQSEYVTAVDSLSEIVQRRFITPWLKPDFLFKMTKLGKKQEQCLKIVH 237 Query: 203 GLTNKVIKNKKETYL 217 T KVI +KE L Sbjct: 238 NFTRKVINERKEDKL 252 >UniRef50_A1BPS2 Cluster: CYP4BF1; n=2; Ips paraconfusus|Rep: CYP4BF1 - Ips paraconfusus Length = 511 Score = 195 bits (475), Expect = 3e-48 Identities = 106/270 (39%), Positives = 154/270 (57%), Gaps = 7/270 (2%) Query: 229 LEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTN 288 L+ T + ++A K L T K +++ +E +G K R AFLDL++ G Sbjct: 245 LKLVTDFTQNVIAERRKELH-TAKKTVQENKSGTEE--IGGKTRRAFLDLLLSIQDEG-- 299 Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATF 348 K++D +I+EEVDT MFEGHDTT++G S+ + L H D Q +V E+ +FG+SDR T Sbjct: 300 KLTDEDIREEVDTFMFEGHDTTSSGMSWTIWCLAHHLDYQNKVIQEIDAVFGNSDRNCTN 359 Query: 349 ADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQP 408 D E+KYLE+ I E++RLYPPVP+I+RK+ D Y +P T++I +LHR P Sbjct: 360 EDLKELKYLEQCIKEAMRLYPPVPLISRKVEED--FHCAGYDVPRDATILISPLVLHRDP 417 Query: 409 KYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRT 468 Y++ E +NP+NF P RH YS+IPFSAGPR+C+G+K+A R + Sbjct: 418 ALYENVESYNPENFSPSAIARRHAYSFIPFSAGPRNCIGQKFALMEERTVLSWFFRRYCV 477 Query: 469 ISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 S IILK ++G +K+ R Sbjct: 478 RSSEEFLSNIPCAKIILKPSKGVPIKIYRR 507 Score = 101 bits (241), Expect = 6e-20 Identities = 57/196 (29%), Positives = 101/196 (51%), Gaps = 7/196 (3%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 V+R WLG IV + ++ +L S+ I K EY + WLG GLLIS+G KWRS RK Sbjct: 75 VVRFWLGPIPIVCAFGPESVKTVLESNKVITKGDEYDILERWLGTGLLISTGNKWRSRRK 134 Query: 90 MIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGI 147 M+ FH N+L F+ +++ + +++++ ++ + FDV ++ +DI+ ET+M Sbjct: 135 MLTMAFHFNVLNGFMDTYDKEARIFLDQIREFADTNEPFDVCPFIKRCALDIICETSMAH 194 Query: 148 SRKTQDESGFDY--AMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205 Q + Y A+A M ++ R FW++ +++ + + L ++ T Sbjct: 195 KIDAQVDHNHPYVNAVAQMNTLSFLYARSPWFWIKP--IWRFFGHEENYERNLKLVTDFT 252 Query: 206 NKVI-KNKKETYLENK 220 VI + +KE + K Sbjct: 253 QNVIAERRKELHTAKK 268 >UniRef50_UPI0000E46144 Cluster: PREDICTED: similar to ENSANGP00000019301; n=5; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ENSANGP00000019301 - Strongylocentrotus purpuratus Length = 469 Score = 192 bits (468), Expect = 2e-47 Identities = 89/187 (47%), Positives = 128/187 (68%), Gaps = 3/187 (1%) Query: 261 FNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCL 320 + D+ ++KR+AFLDL+++ + + I+EEVDT MFEGHDTTAA ++ L L Sbjct: 272 YEDDAVTRKRKRIAFLDLLLQMHREDAT-FTLEAIREEVDTFMFEGHDTTAAAVNWALLL 330 Query: 321 LGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380 +G H VQAR++DE+ Q+FGDS+RP T D E+ YL V+ ESLRL P VP I R L+ Sbjct: 331 IGQHPTVQARLHDEIDQVFGDSERPITSDDLSELSYLSCVVKESLRLLPSVPGIGRDLDE 390 Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440 D+ ++ K V+P G +V + + +H P+ + DPE F+PD FLPEN+ RH +++IPFSA Sbjct: 391 DIIVNGK--VVPKGASVFLSIYGIHHDPEQFPDPERFDPDRFLPENSTKRHPFAFIPFSA 448 Query: 441 GPRSCVG 447 GPR+C+G Sbjct: 449 GPRNCIG 455 Score = 138 bits (333), Expect = 4e-31 Identities = 69/184 (37%), Positives = 107/184 (58%), Gaps = 2/184 (1%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82 Y G VIR+W G IV + +A E ++NS HI+K TEY F +PWLG+GLL S G Sbjct: 72 YRHQSGGVIRMWFGPLPIVLIYNAVHCEALMNSSRHINKGTEYTFMEPWLGKGLLTSGGQ 131 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDIL 140 KW RK++ PTFH +IL+SF+ +FN+ S +V+KL ++ +T ++ ++ +DI+ Sbjct: 132 KWFHRRKLLTPTFHFSILQSFMEVFNEQSMILVKKLGKFADESETVNIFPLVTHCVLDII 191 Query: 141 LETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGI 200 +TAMG Q ++ +Y AV +M +I R F + + ++ T K K L I Sbjct: 192 CDTAMGKRTNAQSDNENEYVKAVGRMSHLIVSRIRNFMLWPDWIYNRTDAGKDHEKALQI 251 Query: 201 IHGL 204 +HG+ Sbjct: 252 LHGM 255 >UniRef50_Q27472 Cluster: Cytochrome p450 family protein 32A1; n=3; Bilateria|Rep: Cytochrome p450 family protein 32A1 - Caenorhabditis elegans Length = 529 Score = 192 bits (468), Expect = 2e-47 Identities = 97/248 (39%), Positives = 150/248 (60%), Gaps = 5/248 (2%) Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSS 315 R +L D N+ EKKR AFLDL++ + Q +SD +I+EEVDT MFEGHDTT++G Sbjct: 276 RKELLNEDGNEASEKKRKAFLDLLL-TIQKEEGTLSDEDIREEVDTFMFEGHDTTSSGIG 334 Query: 316 FVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374 F + LG + + Q ++ EL ++FG ++++P + D + YLE+ I ESLR++P VP+I Sbjct: 335 FTILWLGFYPECQKKLQKELDEVFGFETNQPPSMDDIKKCSYLEKCIKESLRMFPSVPLI 394 Query: 375 ARKLNRDVTI---STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRH 431 AR+L+ DVTI S + V+PAG + R P+ + DP+ +NPDNF + R Sbjct: 395 ARRLSEDVTINHPSGQKIVLPAGLAACVSPIAAARDPRAWPDPDTYNPDNFDIDAIAGRD 454 Query: 432 YYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGF 491 Y+YIPFSAGPR+C+G+K+A R + S E+ + ++IL+ G Sbjct: 455 PYAYIPFSAGPRNCIGQKFALLEQKTILSTFFRKYEVESLQTEENLRPVPELILRPYNGM 514 Query: 492 QMKVEPRK 499 ++K++ R+ Sbjct: 515 KIKIKRRE 522 Score = 111 bits (266), Expect = 6e-23 Identities = 61/192 (31%), Positives = 104/192 (54%), Gaps = 3/192 (1%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 ++ +W+G IVFL ++ I +L S+ +I K ++Y W+G GLL S+ KW RK Sbjct: 93 IMLLWIGPVPIVFLGTSECIRPVLESNTNISKPSQYDKMSEWIGTGLLTSTHEKWFHRRK 152 Query: 90 MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILLETAMGIS 148 M+ PTFH I++ + +F +N+ + + ++ V G FD Y T+DI+ ETAMGI Sbjct: 153 MLTPTFHFTIIQDYFPVFVRNAEVLADAVELHVDGDYFDAFPYFKRCTLDIICETAMGIQ 212 Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKF-WMRSEIVFKLTSFFKQQTKLLGIIHGLTNK 207 Q +Y AV ++ +I+ H KF W+ + ++ LT + + + + + K Sbjct: 213 VNAQLGHNNEYVHAVKRISEIV-WNHMKFPWLWLKPIWYLTGLGFEFDRNVRMTNNFVRK 271 Query: 208 VIKNKKETYLEN 219 VI+ +KE E+ Sbjct: 272 VIQERKELLNED 283 >UniRef50_UPI0000D55952 Cluster: PREDICTED: similar to Cytochrome P450 4d2 (CYPIVD2); n=2; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4d2 (CYPIVD2) - Tribolium castaneum Length = 501 Score = 191 bits (465), Expect = 4e-47 Identities = 102/243 (41%), Positives = 142/243 (58%), Gaps = 8/243 (3%) Query: 252 FKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTA 311 FK +D+ ++E G K+R A LD+++E S NG N ++D +I+EEVDT MFEGHDTT Sbjct: 260 FKLLQDNAKISEE---GIKRRAALLDMLLEVSDNGKN-LTDEDIREEVDTFMFEGHDTTT 315 Query: 312 AGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPP 370 FVL + + DVQ ++YDEL + G D + TF+D E+KYL+ VI E+ RLYPP Sbjct: 316 TSICFVLYAIAQNPDVQKKIYDELVSVLGPDCKKEITFSDIQELKYLDVVIKEAHRLYPP 375 Query: 371 VPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNR 430 VP+I R L D TI IP T + I + ++ Y +P VF+PD FLPE R Sbjct: 376 VPLIERSLEEDCTID--GLTIPKNTNISIFLYGMNYNKDVYPEPHVFDPDRFLPEKQGER 433 Query: 431 HYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEG 490 H ++Y+PFSAGPR+C+G+K+A R F IS P+ ++ +LK G Sbjct: 434 HTFAYVPFSAGPRNCIGQKFALLELKTTIAKLLRCFE-ISPDPKNPPQVGMCSVLKSRNG 492 Query: 491 FQM 493 M Sbjct: 493 IHM 495 Score = 156 bits (379), Expect = 1e-36 Identities = 76/216 (35%), Positives = 128/216 (59%), Gaps = 6/216 (2%) Query: 13 TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72 T L++ + +G V++VWLG +L + + + +E LNS VH++K+ Y FKPWL Sbjct: 53 TVDLLHSFMNLQDKYGTVVKVWLGPRLHLLITKPEMVEFFLNSTVHLNKSDGYDLFKPWL 112 Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI-FNQNSN---NVVEKLKSEVGKTFDV 128 G+GLL+S+G KW++ RK+I PTFH IL++F+ FN+ N +V+ K S+ K+ ++ Sbjct: 113 GDGLLVSTGSKWKTRRKLITPTFHFKILENFLETSFNKQINILLDVLLKEASQTDKSIEI 172 Query: 129 HDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLT 188 H ++ ++DI+ ETA G Q + Y AV +I R + W+R ++F+L+ Sbjct: 173 HSLINLCSLDIICETAFGTELNAQAKCNPKYVEAVTGFLEIFTLRFFSAWLRHPLIFRLS 232 Query: 189 SFFKQQTKLLGIIHGLTNKVIKNKKETY--LENKAK 222 + + + L I+H TN +IK +KE + L++ AK Sbjct: 233 DKYAKYMEYLKILHDFTNTIIKRRKEEFKLLQDNAK 268 >UniRef50_UPI00015B560A Cluster: PREDICTED: similar to cytochrome P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 543 Score = 188 bits (458), Expect = 3e-46 Identities = 136/498 (27%), Positives = 239/498 (47%), Gaps = 31/498 (6%) Query: 13 TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72 T+ +++ T+ + RVWL +L + D + ++ I S I+K Y+F +PWL Sbjct: 57 TEDILSKCQELLDTYPSPFRVWLADRLFYAVYDPEQLKTIFLSPKTIEKEELYKFAEPWL 116 Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDY 131 G GL + KWR HRK+I PTF+ IL+SFV +F+ S ++++++ E+ G FD+ Y Sbjct: 117 GTGLFTAPASKWRIHRKLIMPTFNPRILESFVEVFSVQSEVMIKEMEVELNGGEFDIFHY 176 Query: 132 MSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFF 191 +S T+DI+ ETAMG+ + Q + Y + ++ +I++ R +K W+ +I+F T Sbjct: 177 VSLCTLDIICETAMGVRSRAQTQRNSPYVESAKRLFEIVYSRMFKIWLHPDIIFNNTRLG 236 Query: 192 KQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTV 251 K Q + + +H LT+ VIK KK+ + N T+E ++ K D + Sbjct: 237 KDQRECIKYVHSLTDDVIKRKKQAFEGN-------GTVEGMNGKLPQV-EGKRKAFLDLL 288 Query: 252 FKGYRDDLDFNDE--NDVGEKKRLAFLDLMIESSQNGTNKISDH-EIKEEVDTIMFEGHD 308 + + F DE + + +A D + ++ H EI+++V + E + Sbjct: 289 MELSHEGTKFTDEELREEVDTMMIAGNDTTATVNCFVMLMLASHPEIQDKVYEELCEIY- 347 Query: 309 TTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLY 368 GS +L H+D+ Y L ++ ++ R L + + + + + LY Sbjct: 348 ----GSEDPSSVLVRHEDLHRMEY--LERVIKETMRIFPVGPVLVRRVTDDLNIGNHPLY 401 Query: 369 PPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVF-NPDNF----- 422 + N D Y I T+ G+ ++ K ++ E + +P F Sbjct: 402 FAI----MNCNFDYINQICFYGITGDYTLTKGSSVVLGIIKTHRSEEYWTDPLTFNPDRF 457 Query: 423 LPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF--RTISEIPEKEFKLQ 480 LPE RH Y+YIPFSAGPR+C+G KYA R + + + +P ++ KL+ Sbjct: 458 LPEECAKRHPYTYIPFSAGPRNCLGMKYAMMAMKALLATVIRKYVIKKDNALPVQDIKLK 517 Query: 481 GDIILKRAEGFQMKVEPR 498 D++LK E +++E R Sbjct: 518 ADVMLKPVEPITIRIERR 535 >UniRef50_UPI0000D56049 Cluster: PREDICTED: similar to Probable cytochrome P450 4d14 (CYPIVD14); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Probable cytochrome P450 4d14 (CYPIVD14) - Tribolium castaneum Length = 487 Score = 188 bits (458), Expect = 3e-46 Identities = 104/238 (43%), Positives = 137/238 (57%), Gaps = 9/238 (3%) Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321 N+ G+KK AFLDL+++ S K+SD +I+EEVDT MF GHDTTA G F L LL Sbjct: 253 NETEKSGKKK--AFLDLLLKFSD--IEKLSDRDIREEVDTFMFAGHDTTATGVCFALYLL 308 Query: 322 GIHQDVQARVYDELYQIFGDSDRP-ATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380 + +VQ +V E ++FGD P T+ + MKYLE VI E+LRLYP VPVI R L Sbjct: 309 ANNPEVQEKVLSEQKELFGDEKNPCVTYQELQNMKYLEYVIKETLRLYPSVPVIGRYLKE 368 Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440 D T + VI A T V I + +HR P Y+ +PE F P+ F EN N Y+YIPFSA Sbjct: 369 DTTFGDR--VISAKTNVAIFIYGIHRNPDYFPEPEKFIPERF--ENMTNLPPYAYIPFSA 424 Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 GPR+C+G+K+A R+F P E L + +LK A G ++ + R Sbjct: 425 GPRNCIGQKFAMLEMKSLISKVIRHFELTPANPHHELVLAAETVLKSANGIKIGLRAR 482 Score = 125 bits (301), Expect = 3e-27 Identities = 64/220 (29%), Positives = 116/220 (52%), Gaps = 2/220 (0%) Query: 6 HVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLV-DADDIEIILNSHVHIDKATE 64 H + T +++N+ Y + +G ++++ LG +V D +E L+S+ + K+ Sbjct: 40 HALDAKSTTEILNVTTNYVKKYGKIVKLRLGPFFKALVVTDYKLVEFFLSSNSLLTKSQN 99 Query: 65 YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS-EVG 123 Y F + WLG GL++++G W+ HRK++ P FH+ IL+ ++ F+ +EKLKS + Sbjct: 100 YAFARSWLGNGLILANGTHWKQHRKILTPAFHLEILREYLETFDSVGRIFIEKLKSLDNV 159 Query: 124 KTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEI 183 ++ D+ + T+D++ ETAMG Q +Y +V +MC II R + Sbjct: 160 QSVDLDALVPLCTLDVICETAMGTKINAQKGENSEYVSSVKEMCRIIVARFLSPLKILKC 219 Query: 184 VFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKG 223 + +T F + K++ I+H T+KVI +K E + G Sbjct: 220 TYWMTHDFYTERKVVNILHSFTSKVIDGRKTNRNETEKSG 259 >UniRef50_Q178T9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 511 Score = 188 bits (457), Expect = 4e-46 Identities = 132/491 (26%), Positives = 248/491 (50%), Gaps = 38/491 (7%) Query: 14 QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLG 73 ++L+ L Y + + + +G K+ + L + ++ +LN +K+ Y + L Sbjct: 54 EELLGLLHSYFRQHDRMFAIHIGPKVAIGLSHPELVQQVLNHPYCQEKSNVYELLR--LP 111 Query: 74 EGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDY 131 GLL S W+ HRK + TF++ IL SF+ IFN ++ +++ L + GKTF++ Sbjct: 112 NGLLSSKYKVWKLHRKTLNSTFNLRILNSFLPIFNDSTRKLIQLLDQYASTGKTFNILAP 171 Query: 132 MSGTTVDILLETAMGISRKTQDESGFDYAMAVMK-MCDIIHQRHYKFWMRSEIVFKLTSF 190 ++ T+ ++ ET+ G +K + G + ++ + + +R + SEI+++LT Sbjct: 172 LTHCTLGMVCETSFG--KKVLEREGKEQFFDDLEVLLTSLGKRVVNVLLHSEIIYRLTPM 229 Query: 191 FKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDT 250 ++ +TK + T+KVI+ K+ +E+ G L TLSD Sbjct: 230 YRDETKSRAVCRQFTDKVIEEKR-IEIESSFAG-------------DSSLITTEGTLSDD 275 Query: 251 VFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTT 310 + Y+ F D+ L + LM +S+ N T D EI ++V T++ G++T+ Sbjct: 276 EGEAYKRPQIFIDQ--------LLKMPLMTKSAYNFT----DLEISDQVFTMIIAGNETS 323 Query: 311 AAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTL-EMKYLERVILESLRLYP 369 A + LL ++ +Q + Y E+ Q F +++ AD L ++ Y+E V+ ES+RL P Sbjct: 324 ATQMAHTCLLLAMNPAIQQKAYQEVQQ-FIETENSYIDADILRKLVYIEAVLKESMRLLP 382 Query: 370 PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQ 428 +I+RK +D+ + ++IP T +++ + LHR+P + D E F P+ FL E+++ Sbjct: 383 VGSLISRKNLQDIVLD--GHIIPKNTPLLMKPYSLHRRPDIWGSDAEQFVPERFLGEDSK 440 Query: 429 NRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRA 488 RH Y++IPFS GPR C+G +YA +NF +++ ++ ++ + L A Sbjct: 441 RRHPYAFIPFSGGPRGCIGLRYAMMTLKIMLALILKNFEISTQLKYRDLRIHYQLSLNLA 500 Query: 489 EGFQMKVEPRK 499 + +E R+ Sbjct: 501 GPHAVSLERRR 511 >UniRef50_Q9U1R5 Cluster: Putative uncharacterized protein cyp-42A1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein cyp-42A1 - Caenorhabditis elegans Length = 511 Score = 186 bits (453), Expect = 1e-45 Identities = 85/230 (36%), Positives = 149/230 (64%), Gaps = 6/230 (2%) Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329 ++R+AFLDLM++ + G ++ I EEVDT FEGHDTT+A ++ L L+G + ++Q+ Sbjct: 280 RRRMAFLDLMLDMNSKG--ELPMEGICEEVDTFTFEGHDTTSAAMNWFLHLMGANPEIQS 337 Query: 330 RVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389 +V E+ ++ G++DRP ++ D ++KYLE E+LRLYP VP+IAR+ D+ + + + Sbjct: 338 KVQKEIDEVLGEADRPVSYEDLGKLKYLEACFKETLRLYPSVPLIARQCVEDIQV--RGH 395 Query: 390 VIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449 +P+GT VV+ M+H+ P+Y+ DPE+FNP+ F+ + +H Y+YIPFSAG R+C+G + Sbjct: 396 TLPSGTAVVMVPSMVHKDPRYWDDPEIFNPERFI--TGELKHPYAYIPFSAGSRNCIGMR 453 Query: 450 YAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 +A +N + +++ E ++ ++I++ G ++K E R+ Sbjct: 454 FAMMEEKCILAIILKNLKVKAKLRTDEMRVAAELIIRPLYGNELKFEKRE 503 Score = 128 bits (310), Expect = 3e-28 Identities = 70/210 (33%), Positives = 111/210 (52%), Gaps = 2/210 (0%) Query: 6 HVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY 65 H E ++ +A + + RVWLG V L A ++E IL S ++K Y Sbjct: 50 HFSPEEFFEQSQGIAYMMRKGDERITRVWLGGLPFVLLYGAHEVEAILGSPKMLNKPFLY 109 Query: 66 RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSE--VG 123 F W+G+GLLIS KWR RK++ PTFH +ILK FV ++N++ ++ K +++ G Sbjct: 110 GFLSAWIGDGLLISKPDKWRPRRKLLTPTFHYDILKDFVEVYNRHGRTLLSKFEAQAGTG 169 Query: 124 KTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEI 183 + DV ++ T+D++ E A+G S Q + Y AV KM DI+ QR + S+ Sbjct: 170 EYSDVFHTITLCTLDVICEAALGTSINAQKDPHSPYLDAVFKMKDIVFQRLLRPHYFSDT 229 Query: 184 VFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213 +F L K+ + + I+H T+K I +K Sbjct: 230 IFNLIGPGKEHDECVKILHEFTSKAIYARK 259 >UniRef50_Q7YXL0 Cluster: Cytochrome P450 monooxygenase; n=2; Tribolium castaneum|Rep: Cytochrome P450 monooxygenase - Tribolium castaneum (Red flour beetle) Length = 491 Score = 183 bits (445), Expect = 1e-44 Identities = 91/230 (39%), Positives = 132/230 (57%), Gaps = 4/230 (1%) Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329 +KRLA LDL+++ G N I D I+EEVDT MFEGHDTT+ + L LL H++VQ Sbjct: 264 RKRLAMLDLLLKYKSEGAN-IDDEGIREEVDTFMFEGHDTTSVSICYTLMLLANHREVQE 322 Query: 330 RVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389 + E+ + + P T+A E+K+++RVI ESLRLYP VP I+R ++ T Y Sbjct: 323 EILKEMEAVL--DEEPPTYAKLQELKFMDRVIKESLRLYPSVPFISRVSGSEIQTKT-GY 379 Query: 390 VIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449 IP V + + +H P + DPE F+PD FLPEN Q RH ++YIPFSAG R+C+G+K Sbjct: 380 TIPKDCMVNLQIYDMHHNPNVFPDPEKFDPDRFLPENIQKRHPFAYIPFSAGSRNCIGQK 439 Query: 450 YAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 +A + F + K+ D++L+ ++K PR+ Sbjct: 440 FAMLEIKTVLCGILKKFILEAVDTRKDMAFVSDLVLRPKGSIKVKFVPRR 489 Score = 122 bits (295), Expect = 2e-26 Identities = 62/177 (35%), Positives = 102/177 (57%), Gaps = 1/177 (0%) Query: 41 VFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINIL 100 V L++ +D+E++L K+ Y F WLG GLL S GPKW++ RK++ P FH NIL Sbjct: 80 VNLLNPEDVELVLTDTKQNTKSFIYHFLHSWLGTGLLTSRGPKWQNRRKILTPAFHFNIL 139 Query: 101 KSFVGIFNQNSNNVVEKLKSEVGKTF-DVHDYMSGTTVDILLETAMGISRKTQDESGFDY 159 + F+ IFN+ + +VE L++E K + DV ++ T+ + ETAMGI D Y Sbjct: 140 QEFIQIFNEETKRLVEDLEAESHKPYIDVVVPITQFTLLSIGETAMGIKLNASDNDKDGY 199 Query: 160 AMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETY 216 AV K+ ++ R + W+ +E ++ LT +++ K+L +H +N VI +K+ + Sbjct: 200 KRAVYKIGQLLTYRAPRPWIHNETIYSLTPQGRKEQKVLKSLHSFSNNVIAERKKHF 256 >UniRef50_Q8ISJ7 Cluster: Cytochrome P450 CYP4L4; n=4; Noctuidae|Rep: Cytochrome P450 CYP4L4 - Mamestra brassicae (Cabbage armyworm) Length = 492 Score = 182 bits (442), Expect = 3e-44 Identities = 95/239 (39%), Positives = 141/239 (58%), Gaps = 9/239 (3%) Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321 ND +D+G K + FLDL++ + +G KI D ++EEVDT MFEGHDTT +G + L L Sbjct: 262 NDSSDIGTKNKHTFLDLLLLAEIDG-KKIDDESVREEVDTFMFEGHDTTTSGIVYTLHCL 320 Query: 322 GIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380 +DVQ ++Y+EL IFG + R T+ + +MKYLE VI ES+RL+PPVP+I R++ + Sbjct: 321 SKRRDVQEKIYEELKTIFGSEIHRDPTYHELQQMKYLELVIKESMRLFPPVPLIERRIMK 380 Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440 D + V GT+VV+ F + RQP + DP F P+ F ++ +S++ FSA Sbjct: 381 DCEVGGLKLV--KGTSVVMNIFQIQRQPDLFDDPLEFRPERF---EAPLKNPFSWLAFSA 435 Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 GPR+C+G+K+A +NF + E E L D++L+ G +K PRK Sbjct: 436 GPRNCIGQKFAMMELKITISEIVKNFFILPAAEEPE--LSADLVLRSKNGVNVKFLPRK 492 Score = 121 bits (292), Expect = 4e-26 Identities = 60/202 (29%), Positives = 109/202 (53%), Gaps = 1/202 (0%) Query: 13 TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72 + + +NL ++ +G+ RV S V + + E +++S HI K Y F WL Sbjct: 49 SSEFLNLVQRLSEKYGHAFRVHFFSTPYVVICHSKYAEPLVSSTEHITKGRSYSFLTCWL 108 Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDY 131 G+GLL ++G +W+SHRK + P FH NIL++F+ +F +N + EK++ G+ D+ Sbjct: 109 GQGLLTATGQRWKSHRKFLTPAFHFNILQNFLPVFCKNQRILTEKIRGMADGRPIDMFPI 168 Query: 132 MSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFF 191 ++ +D + E+ MG+ Q S +Y ++ ++ I+ R + + +F L + Sbjct: 169 IALAALDNVNESIMGVCMDAQKHSQSEYVKSIEELSAIVTMRMQIPFFGEDAIFNLLPYK 228 Query: 192 KQQTKLLGIIHGLTNKVIKNKK 213 +Q K L ++HG TNKVI ++ Sbjct: 229 TKQDKALKVLHGQTNKVINARR 250 >UniRef50_UPI00015B61D7 Cluster: PREDICTED: similar to Cytochrome P450, partial; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to Cytochrome P450, partial - Nasonia vitripennis Length = 342 Score = 181 bits (440), Expect = 5e-44 Identities = 83/189 (43%), Positives = 126/189 (66%), Gaps = 2/189 (1%) Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 D +++G++K FLD +++ S+ N +S EI+E+VDT MF GHDTT S+VL LG Sbjct: 114 DNDNIGKRKPKVFLDRLMDLSEADENPLSLEEIREQVDTFMFGGHDTTGITISWVLFSLG 173 Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382 +VQ +V++EL + G ++PAT ++KYL+RVI E+LR+YP P++ R L+ + Sbjct: 174 NAPEVQRKVHEELDNVIGIGNQPATKEQLSQLKYLDRVIKETLRIYPSAPMVGRILDHNT 233 Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442 I ++IP G V + LHR P+ + P+ FNPD FLPE++ RH Y+Y+PFSAGP Sbjct: 234 VID--GHIIPKGVVVNLQILHLHRDPEIWDAPDKFNPDRFLPESSNGRHPYAYVPFSAGP 291 Query: 443 RSCVGRKYA 451 R+C+G+K+A Sbjct: 292 RNCIGQKFA 300 Score = 58.8 bits (136), Expect = 3e-07 Identities = 28/75 (37%), Positives = 39/75 (52%) Query: 50 EIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQ 109 ++IL S K+ Y FF WLG GLL SSG W +R+++ P FH ++L F I + Sbjct: 3 QVILKSQTLTRKSNIYEFFAYWLGNGLLTSSGDVWHRNRRLMTPAFHFSMLDQFSEIITE 62 Query: 110 NSNNVVEKLKSEVGK 124 +K EV K Sbjct: 63 KVELFNNCIKMEVDK 77 >UniRef50_UPI0000D56462 Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily v, polypeptide 2; n=2; Tribolium castaneum|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily v, polypeptide 2 - Tribolium castaneum Length = 814 Score = 180 bits (439), Expect = 6e-44 Identities = 91/228 (39%), Positives = 136/228 (59%), Gaps = 6/228 (2%) Query: 267 VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326 V E+K+ FLD+++ N ++S E+++EV T + G DT A FVL LLG+HQD Sbjct: 587 VVEEKKRPFLDVLVGKYLN--EELSYQELEDEVSTFLLAGSDTNATAGCFVLTLLGMHQD 644 Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386 VQ ++Y+E+ ++ G P T D ++KY ERVI E+LRL+P P IAR + D+ + Sbjct: 645 VQEKLYEEIIEVLGPEKYP-TLDDLPKLKYTERVIKETLRLFPGAPFIARIASDDIDLG- 702 Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446 +YVIP G+ + +G LHR KY+++P FNP+ FLPEN RH Y+++PFS G R+CV Sbjct: 703 -DYVIPRGSNIAVGYVHLHRSEKYWEEPLKFNPERFLPENVAKRHPYTWLPFSGGLRNCV 761 Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPE-KEFKLQGDIILKRAEGFQM 493 G K+ R FR S + + +L +I+LK GF++ Sbjct: 762 GGKFGMMVMKIMISMIIRKFRVKSSVKSVGDIELTANIVLKPKNGFRL 809 Score = 62.1 bits (144), Expect = 3e-08 Identities = 33/132 (25%), Positives = 69/132 (52%), Gaps = 2/132 (1%) Query: 84 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLE 142 W+ HR++I PT + +IL +F I Q + ++E L+ + K D + +++ VD++ E Sbjct: 433 WKKHRRIIVPTLNQSILNTFPQIICQQCDILLEILEKKCDKGEIDHYKFVTNFAVDVVSE 492 Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202 T G+ Q +Y+ K+ +++ R ++ S+ +F T +K + + + ++ Sbjct: 493 TIFGVPLNAQITDA-NYSRTFDKIMEVVFMRIFRVDYHSDFLFSWTKEYKAEQENVKLVK 551 Query: 203 GLTNKVIKNKKE 214 T +I+ KKE Sbjct: 552 ETTRDLIERKKE 563 >UniRef50_Q8ISJ8 Cluster: Cytochrome P450 CYP4S4; n=3; Noctuidae|Rep: Cytochrome P450 CYP4S4 - Mamestra brassicae (Cabbage armyworm) Length = 492 Score = 180 bits (438), Expect = 8e-44 Identities = 94/228 (41%), Positives = 138/228 (60%), Gaps = 7/228 (3%) Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 D+ +G KKR A LDL++E+ G +I I+EEV+T+MFEGHDTTA L L+ Sbjct: 263 DDVSIGGKKRYAMLDLLLEAENKG--EIDLEGIREEVNTLMFEGHDTTAMAIVLGLMLIA 320 Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382 H++VQ R+++E +I GDSDR T +D +MKYLE VI E+LRLYP VP IAR++ D Sbjct: 321 DHEEVQDRIFEECQKILGDSDRTPTMSDLADMKYLEAVIKETLRLYPSVPFIAREITEDF 380 Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442 + + + G+ V I + LHR+P + +P+ F PD FL + H Y+++PFSAGP Sbjct: 381 MLD--DLPVKKGSEVSIHIYDLHRRPDLFPEPDAFIPDRFL--SGAPMHPYAFVPFSAGP 436 Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEG 490 R+C+G+++A RNFR ++ L D+++ R EG Sbjct: 437 RNCIGQRFAMLEMKCVFSAICRNFRLAPKVQGYRPALLADMLI-RPEG 483 Score = 116 bits (280), Expect = 1e-24 Identities = 59/195 (30%), Positives = 106/195 (54%), Gaps = 1/195 (0%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82 Y + +G+ + + + I+ L + D+E++L+ +I K+ Y F + WLG GLL+SSG Sbjct: 59 YKKEYGDRYVIKMMKRRILHLSNEKDVEVVLSHSRNIKKSKPYTFLEAWLGTGLLLSSGA 118 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLE 142 KW RK++ PTFH NILKSF + + S ++VE L + G ++ +S T+ + E Sbjct: 119 KWHRRRKILTPTFHFNILKSFTVVMKEKSRSLVETLNNLEGTEVNLLPVISDYTLYTICE 178 Query: 143 TAMGISRKTQDES-GFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGII 201 TAMG S +Y A++++ +++ R + W+ +E +FK ++ L + Sbjct: 179 TAMGTQLDADKSSKTLEYKTAILEIGNLLLGRLTRVWLHNEYLFKKFPIGRRFENCLEKV 238 Query: 202 HGLTNKVIKNKKETY 216 H + VI +K+ + Sbjct: 239 HSFADDVIMERKKNW 253 >UniRef50_O17851 Cluster: Putative uncharacterized protein cyp-37B1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein cyp-37B1 - Caenorhabditis elegans Length = 509 Score = 178 bits (433), Expect = 3e-43 Identities = 90/230 (39%), Positives = 135/230 (58%), Gaps = 4/230 (1%) Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328 +K+ +AFLDL++E G +++ +I+EEVDT MFEGHDTT+A + L L + + Q Sbjct: 280 DKRSMAFLDLLLELRNEGL--MNEDDIREEVDTFMFEGHDTTSASMGWTLWCLAHNPEFQ 337 Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 +V E+ IFG SDR T D +MKYLE+ + ESLR+YP VP R + +DV I+ Sbjct: 338 EKVIQEVDGIFGTSDRDCTNDDLKQMKYLEKCLKESLRMYPSVPFFGRTVEQDVVINGDF 397 Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 + P G +++ +L R P + +P +NP+NF + +RH YS IPFSAGPR+C+G+ Sbjct: 398 F--PKGVRIIVMPLLLQRNPLIFDNPNQYNPENFSEDKIGSRHAYSDIPFSAGPRNCIGQ 455 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 K+A R +R + P K+ ++ILK + GF + V R Sbjct: 456 KFAMMEEKAVISWFFRKYRVTASQPFGMNKILPELILKSSLGFPLTVHHR 505 Score = 117 bits (281), Expect = 8e-25 Identities = 62/206 (30%), Positives = 107/206 (51%), Gaps = 2/206 (0%) Query: 13 TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72 T + + LA Y Q I +WLG ++ +++ + IL S+ I KA EY PWL Sbjct: 63 TTQSMELAQYYCQKGCGTIGLWLGPVPLIAVINPQHAKEILESNEVITKAEEYDILFPWL 122 Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHD 130 G GLL S+G KWR RKM+ P FH +L F+ + + + +E++K ++ GK D+ Sbjct: 123 GTGLLTSTGSKWRQRRKMLTPAFHFKVLNDFLSVHDYQAKVFLEQIKPYADSGKEVDLFP 182 Query: 131 YMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSF 190 Y+ +D++ +T+MG++ Q+ Y +V + + + + W+R + ++ LT Sbjct: 183 YIKRLALDVICDTSMGVTIDAQNNHDHQYVESVRLLSEYAFEWILRPWLRLKPLWYLTGP 242 Query: 191 FKQQTKLLGIIHGLTNKVIKNKKETY 216 + + L I+ T VIK K E + Sbjct: 243 GHEYDRHLKIVTDFTKTVIKEKWEEF 268 >UniRef50_A1BPS5 Cluster: CYP4BJ1; n=1; Ips paraconfusus|Rep: CYP4BJ1 - Ips paraconfusus Length = 464 Score = 178 bits (433), Expect = 3e-43 Identities = 82/182 (45%), Positives = 123/182 (67%), Gaps = 4/182 (2%) Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328 EKKRLAFLDL+++ Q T +++D +I+EEVDT MFEGHDT ++ F + + +Q Sbjct: 285 EKKRLAFLDLLLDL-QYETGRLNDEDIREEVDTFMFEGHDTVSSSMGFFVFSMSQRLHLQ 343 Query: 329 ARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387 +VY+E+ +IFG D +R T D +MKYLE+ I E +RL P VP+I R ++ D I Sbjct: 344 EKVYEEMLEIFGNDEERDVTSEDISQMKYLEQCIREVMRLLPTVPIIGRIISEDTNIG-- 401 Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447 Y++P TT +I F + R ++Y +P+ F+PD+F PE + R+ ++YIPFSAGPR+C+G Sbjct: 402 GYMVPKNTTAMIAPFAVQRDKRFYHNPDAFDPDHFTPERVKQRNPFAYIPFSAGPRNCIG 461 Query: 448 RK 449 +K Sbjct: 462 QK 463 Score = 107 bits (257), Expect = 7e-22 Identities = 47/121 (38%), Positives = 74/121 (61%), Gaps = 2/121 (1%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 ++RVW+G K +VF+ + ++IL S I K EY + WLG GLL S+G KW + RK Sbjct: 81 IMRVWIGPKPLVFIYKPETAKVILESQTLITKPGEYGILERWLGTGLLTSTGEKWHTRRK 140 Query: 90 MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLETAMGI 147 M+ PTFH +IL +F+ +FN+ +N ++E L G FD + + +D++ E AMG+ Sbjct: 141 MLTPTFHFSILNNFMKVFNRQANTLIENLDRHAADGYPFDFYKVIKALALDVICEAAMGM 200 Query: 148 S 148 + Sbjct: 201 N 201 >UniRef50_Q9N4Q5 Cluster: Cytochrome p450 family protein 32B1; n=2; Caenorhabditis|Rep: Cytochrome p450 family protein 32B1 - Caenorhabditis elegans Length = 516 Score = 176 bits (428), Expect = 1e-42 Identities = 93/241 (38%), Positives = 145/241 (60%), Gaps = 4/241 (1%) Query: 265 NDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324 ++ E K+LAFLD +++S + + ++D I+EEVDT MFEGHDTT++G +F + LG Sbjct: 276 SEQNETKKLAFLDYLLKSQEEHPDILTDEGIREEVDTFMFEGHDTTSSGITFAVWFLGQF 335 Query: 325 QDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383 + Q RV+DEL +IFG D +R D +M YLE+ I E+LR+ PPVP ++RKL DV Sbjct: 336 PEYQQRVHDELDEIFGEDFERIPNSEDIQKMVYLEQCIKETLRMTPPVPFVSRKLTEDVK 395 Query: 384 I--STK-NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440 I +TK + ++PAG +I + + +Y++ P F P++F PE R ++++PFSA Sbjct: 396 IPHATKPDLLLPAGINCMINIITIMKDARYFERPYEFFPEHFSPERVAAREPFAFVPFSA 455 Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500 GPR+C+G+K+A RNF S E ++ILK G Q+ + R++ Sbjct: 456 GPRNCIGQKFALLEEKVLLSWIFRNFTVTSMTKFPEEMPIPELILKPQFGTQVLLRNRRK 515 Query: 501 V 501 + Sbjct: 516 L 516 Score = 115 bits (276), Expect = 3e-24 Identities = 61/189 (32%), Positives = 109/189 (57%), Gaps = 6/189 (3%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 V+++WLG V + + +I+L+S V+I K+++Y K W+G+GLLIS+G KWRS RK Sbjct: 83 VLKLWLGPIPAVNIARGEIAKIVLDSSVNISKSSQYNKLKEWIGDGLLISTGDKWRSRRK 142 Query: 90 MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGI 147 M+ TFH +LK + IF +VE L+ +FD+ Y+ +DI+ ETAMG Sbjct: 143 MLTQTFHFAVLKEYQKIFGAQGKILVEVLQLRANNKFSFDIMPYIKRCALDIICETAMGC 202 Query: 148 SRKTQDESGFDYAMAVMKMCDII--HQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205 S +Q + +Y +V ++ +I+ +++ +FW++ ++ L + + + + T Sbjct: 203 SISSQRGANDEYVNSVRRLSEIVWNYEKAPQFWLKP--IWYLFGDGFEFNRHVKLTTDFT 260 Query: 206 NKVIKNKKE 214 VI+N+K+ Sbjct: 261 RDVIENRKK 269 >UniRef50_Q9VXY0 Cluster: Probable cytochrome P450 4s3; n=5; Acalyptratae|Rep: Probable cytochrome P450 4s3 - Drosophila melanogaster (Fruit fly) Length = 495 Score = 175 bits (426), Expect = 2e-42 Identities = 88/236 (37%), Positives = 142/236 (60%), Gaps = 12/236 (5%) Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 +++DVG K+RLAFLD+++ + G ++SD +I+EEVDT MFEGHDTT++ +F L LL Sbjct: 265 EQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLS 324 Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382 + DVQ R ++E ++ G + M YLE VI E+LR+YP VP +RK+ D+ Sbjct: 325 KNPDVQQRAFEEASELEG--------REKESMPYLEAVIKETLRIYPSVPFFSRKVLEDL 376 Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442 + +P G ++ +MLHR PK + DPE F+PD FL N + H +++ FSAGP Sbjct: 377 EVG--KLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFL-VNEKQMHPFAFAAFSAGP 433 Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 R+C+G+K+A R++R + + + + K +++ K G ++++ PR Sbjct: 434 RNCIGQKFAMLELKTSLAMLLRSYRFLPD-KDHQPKPLAELVTKSGNGIRLRILPR 488 Score = 151 bits (366), Expect = 4e-35 Identities = 66/207 (31%), Positives = 119/207 (57%), Gaps = 1/207 (0%) Query: 15 KLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGE 74 +++N + G V R+W G L+V D +DI+ +L ++ + K+ Y +PWLG+ Sbjct: 51 EILNWLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGK 110 Query: 75 GLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMS 133 GLL + G W RK++ P FH IL F +N +V +L+++ G++FD++ Y++ Sbjct: 111 GLLTNGGESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKANGESFDIYPYIT 170 Query: 134 GTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQ 193 +D + ETAMGI + Q +S +Y AV +C ++H++ + FW R + FK T K+ Sbjct: 171 LFALDAICETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKE 230 Query: 194 QTKLLGIIHGLTNKVIKNKKETYLENK 220 + L ++H TN+VI+ ++E ++ + Sbjct: 231 REAALKVLHDETNRVIRLRREQLIQER 257 >UniRef50_A1BPS4 Cluster: CYP4BH1; n=1; Ips paraconfusus|Rep: CYP4BH1 - Ips paraconfusus Length = 499 Score = 174 bits (424), Expect = 4e-42 Identities = 95/261 (36%), Positives = 145/261 (55%), Gaps = 5/261 (1%) Query: 238 EILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKE 297 EIL N ++ + K + L ++DVG K+++AFLDL++ ++ +G + EI+ Sbjct: 242 EILHNFTNSVINKRRKETTEQLKNVKQDDVGRKRKMAFLDLLLSTNIDGRPPTQE-EIRC 300 Query: 298 EVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKY 356 EVDT MF GHDTT++ S +L +Q V DEL +FG D T E+KY Sbjct: 301 EVDTFMFAGHDTTSSAMSSAFYVLAKKTQIQKMVRDELQGVFGKDGSTQITHKSLQELKY 360 Query: 357 LERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEV 416 LE I E LRLYPP VI+R DV KN+ IP T + + + +R P Y+++ E Sbjct: 361 LELFIKEVLRLYPPATVISRVTEEDVQY--KNHTIPKNTLIEMLIYSANRDPDYHENAEE 418 Query: 417 FNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKE 476 F P+ FL + + R + +YIPFSAGPR+C+G+K+A NF + IPE+E Sbjct: 419 FKPERFLDTSGKKRPF-AYIPFSAGPRNCIGQKFAMLEMKTIISKVLMNFEVLPSIPERE 477 Query: 477 FKLQGDIILKRAEGFQMKVEP 497 + +++LK G ++++P Sbjct: 478 MVMTTEVVLKAKNGVHVQLKP 498 Score = 150 bits (364), Expect = 7e-35 Identities = 71/174 (40%), Positives = 111/174 (63%), Gaps = 3/174 (1%) Query: 45 DADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFV 104 D D ++++L+S+ + K +YR PWLG+GLL S+G +W+SHRKMI P FH +IL+ FV Sbjct: 86 DHDLLDLVLSSNKILTKGGDYRTTAPWLGQGLLTSNGLQWKSHRKMITPAFHFSILEQFV 145 Query: 105 GIFNQNSNNVVEKLKSE-VGKT-FDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMA 162 IFN + +V KL+ + + KT D++ Y++ +DI+ ETAMG++ +Q+ +Y A Sbjct: 146 DIFNSQGDTLVNKLQRDALEKTSIDIYQYVTACALDIICETAMGVNLNSQENHDLEYVQA 205 Query: 163 VMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVI-KNKKET 215 V MC II R + W + ++ L+ K+Q ++L I+H TN VI K +KET Sbjct: 206 VKDMCRIIMDRTFSLWKSFDCLYNLSKLGKKQEQVLEILHNFTNSVINKRRKET 259 >UniRef50_UPI0000D55B03 Cluster: PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1) - Tribolium castaneum Length = 492 Score = 173 bits (422), Expect = 7e-42 Identities = 89/230 (38%), Positives = 134/230 (58%), Gaps = 7/230 (3%) Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 FLD ++E + + +D E+ E +++ G D TA S+ L +L + QD+Q +VY+E Sbjct: 262 FLDYLVELTDR-EGRWTDEELTNETRSVIMAGSDATALTLSYCLVMLAMFQDIQDKVYEE 320 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 L +FGDSDR T D ++YL+R I E+LR++P +I R+L D+TI + IP G Sbjct: 321 LCSVFGDSDRFVTVDDLPHLQYLDRFIKETLRVFPVTSMIGRELTTDMTID--GHFIPKG 378 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454 T++ +HR P+YY DP F+PD FLPE RH ++IPFS GPR+C+G +YA Sbjct: 379 TSIGFPILYIHRNPEYYPDPLKFDPDRFLPEEVAKRHPCTFIPFSFGPRNCIGYRYAMMT 438 Query: 455 XXXXXXXXXRNFRTISEIPEK---EFKLQGDIILKRAEGFQMKVEPRKRV 501 R+F+ + P K E K++ DI K EG+ +++E RK V Sbjct: 439 MKVILATLLRSFKMV-HTPYKEISELKIKFDIATKVDEGYPVRMELRKNV 487 Score = 104 bits (249), Expect = 6e-21 Identities = 63/228 (27%), Positives = 113/228 (49%), Gaps = 6/228 (2%) Query: 13 TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72 T ++ + + + ++WLG+KL +F + DDI++ILN ++K YR+ K Sbjct: 50 THNILENTVRVVSKYRPLCKLWLGNKLTIFPSNPDDIQMILNRS--LEKEEGYRYIKTVF 107 Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHD 130 G GL S +W+ HRK+I T + +L SF+ +N + ++EKLK + G+ D+ Sbjct: 108 GHGLFTSPVSEWKGHRKVIVSTLNQQVLNSFMDTYNIYTRELIEKLKIDTKDGQHIDMFP 167 Query: 131 YMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSF 190 M+ T+DI+ + MG E + M + ++ ++ R + ++ E+ +KL+ Sbjct: 168 IMTQCTLDIICSSIMGTQMNAMKEES-QFIMWMTRVAELAIIRMFNIYLWPELFWKLSPI 226 Query: 191 FKQQTKLLGIIHGLTNKVIKNKKETYLE-NKAKGIIPPTLEEFTHHSG 237 K+ +L I+ VI NK+ L+ + K I L E T G Sbjct: 227 SKESHELDQKIYNYVKTVIHNKRHKGLKSHTGKKIFLDYLVELTDREG 274 >UniRef50_Q9VMS9 Cluster: Probable cytochrome P450 4ac1; n=5; Sophophora|Rep: Probable cytochrome P450 4ac1 - Drosophila melanogaster (Fruit fly) Length = 509 Score = 169 bits (412), Expect = 1e-40 Identities = 84/234 (35%), Positives = 138/234 (58%), Gaps = 5/234 (2%) Query: 265 NDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324 ++ G K+R A LD ++ + +G +I I +EV+T MFEG+DTT+ F L +L +H Sbjct: 279 DEFGRKQRYAMLDTLLAAEADG--QIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALH 336 Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384 +DVQ + Y+E+ + DSD + F ++ YLE VI ESLR++P VP I R+ + + Sbjct: 337 EDVQKKCYEEVENLPEDSDDISMFQFN-KLVYLECVIKESLRMFPSVPFIGRQCVEETVV 395 Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRS 444 + V+P T + I + + R P+++ P++F PD FLPENT NRH ++Y+PFSAG R+ Sbjct: 396 N--GMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPENTVNRHPFAYVPFSAGQRN 453 Query: 445 CVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 C+G+K+A RNF+ + ++ + I+L+ E ++K+ R Sbjct: 454 CIGQKFAILEMKVLLAAVIRNFKLLPATQLEDLTFENGIVLRTQENIKVKLSKR 507 Score = 95.5 bits (227), Expect = 3e-18 Identities = 48/178 (26%), Positives = 95/178 (53%), Gaps = 1/178 (0%) Query: 43 LVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKS 102 +V ++ E + S I K Y +P+LG+GLLIS+ KW S RK + P FH N+L+S Sbjct: 98 VVRPEEAEEVFQSTKLITKNVVYELIRPFLGDGLLISTDHKWHSRRKALTPAFHFNVLQS 157 Query: 103 FVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMA 162 F+GIF + + L+ + +++ + T++ + ETA+G+ E G +Y A Sbjct: 158 FLGIFKEECKKFLNVLEKNLDAELELNQVIPPFTLNNICETALGVKLDDMSE-GNEYRKA 216 Query: 163 VMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENK 220 + + +++ QR M F + +++ + L I+H ++++I+ K++ + + + Sbjct: 217 IHAIEEVLIQRVCNPLMYYNWYFFVYGDYRKHLQNLRIVHDFSSRIIERKRQQFQQKQ 274 >UniRef50_Q16IS6 Cluster: Cytochrome P450; n=12; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 510 Score = 167 bits (405), Expect = 8e-40 Identities = 89/244 (36%), Positives = 134/244 (54%), Gaps = 7/244 (2%) Query: 259 LDFNDEND-VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFV 317 ++ +EN + KKR A LD ++ + Q I + I+EEVDT FEGHDTTAA F+ Sbjct: 270 VELTEENIYLNPKKRYAMLDSLLLAEQK--QLIDEAGIREEVDTFAFEGHDTTAAALVFI 327 Query: 318 LCLLGIHQDVQARVYDELYQIFGD---SDRPATFADTLEMKYLERVILESLRLYPPVPVI 374 L VQ R+Y E+ Q++ + S R T D EMK+L+R + E LRL+PPV I Sbjct: 328 FFTLAREPAVQDRIYREILQVYSNKPQSSRAFTPQDYSEMKFLDRALKECLRLWPPVTFI 387 Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434 +R ++ D+ + + +IPAG I +H P+ + DPE F+ D FLPE R+ Y+ Sbjct: 388 SRSISEDIILDDGS-LIPAGCVANIHIMDMHHDPEQFPDPERFDADRFLPEQVDRRNPYA 446 Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMK 494 Y+PFSAGPR+C+G+KYA FR + ++ D++L+ +++ Sbjct: 447 YVPFSAGPRNCIGQKYAMMELKVVVVNALLKFRVLPVTKLEDINFVADLVLRSTNPIEVR 506 Query: 495 VEPR 498 E R Sbjct: 507 FERR 510 Score = 100 bits (239), Expect = 1e-19 Identities = 61/201 (30%), Positives = 106/201 (52%), Gaps = 6/201 (2%) Query: 23 YAQTFGNVIRVWLGSKLIVF-LVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSG 81 + + +G R W S L V +V + E IL+S +IDK+ Y+F P+LG GLL S+G Sbjct: 67 WPKRYGGSYRFWFSSTLYVLNVVRVREAEHILSSTRNIDKSRFYKFLHPFLGLGLLNSNG 126 Query: 82 PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFD--VHDYMSGTTVDI 139 KW R+++ P+FH NIL F F + + ++ + V K + MS T++ Sbjct: 127 SKWMHRRRILTPSFHFNILNGFHHTFVEECDQLLATIDEHVDKGVPTALQPVMSKFTLNT 186 Query: 140 LLETAMGISRKTQDESGFD-YAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLL 198 + ET+MG+ K SG D Y + ++ +++ R + W+ ++ + +LT + KLL Sbjct: 187 ICETSMGV--KLSTVSGADVYRTKLYEIGEVLVHRLMRPWLLNDFLCRLTGYKAAFDKLL 244 Query: 199 GIIHGLTNKVIKNKKETYLEN 219 +H T +I K++ + E+ Sbjct: 245 LPVHLFTTGIINMKRKQFQES 265 >UniRef50_UPI00015B5E04 Cluster: PREDICTED: similar to CG8302-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CG8302-PA - Nasonia vitripennis Length = 508 Score = 166 bits (404), Expect = 1e-39 Identities = 84/230 (36%), Positives = 129/230 (56%), Gaps = 4/230 (1%) Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330 K+ + L+ M+E+S+ SD +I E T M G D+ ++ L LL H D Q + Sbjct: 277 KKTSLLEYMMETSERNPEWFSDEDIINECCTFMLAGQDSVGTATAMTLFLLANHPDWQDK 336 Query: 331 VYDELYQIF--GDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 +EL +IF G+++RP T D M++LE I E+LRLYP VP+ ARKL DV + Sbjct: 337 CREELDEIFAEGETNRPPTMQDLRAMRWLECCIKEALRLYPSVPIFARKLGEDVKVG--K 394 Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 +VIP+G V+I + HR P ++ DP F P+ F PEN++ RH Y+Y+PFSAGPR+C+G Sbjct: 395 HVIPSGCGVIILPYSTHRLPHHFPDPHSFRPERFSPENSEKRHPYAYLPFSAGPRNCIGN 454 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 K+A R +R + E + + + ++ + G +K+ R Sbjct: 455 KFAILEMKAVISAILRRYRLGGVEGKTEVRPKFRLTVRASGGLWLKISQR 504 Score = 101 bits (241), Expect = 6e-20 Identities = 54/190 (28%), Positives = 103/190 (54%), Gaps = 3/190 (1%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86 +G V R W+ V L++ DDI+ +L S H K YR +LG+GL+ S WR+ Sbjct: 77 YGPVARFWVTLIPYVILLEPDDIQAVLGSAKHTSKIFVYRLLDNFLGKGLITSDVDTWRT 136 Query: 87 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMG 146 HR+++ P FH+++L+ FVG F + ++ + ++L + D+ +++ +IL ET +G Sbjct: 137 HRRLLQPAFHLHVLQKFVGSFAERADRLADRLARYDNQQLDITKFVNDAVYEILNETVLG 196 Query: 147 IS-RKTQDESG-FDY-AMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHG 203 ++ T +E G D + K ++ R + W+ + ++KLTS +Q+ K + Sbjct: 197 VNVASTANEDGVVDLDDLPFRKGQVLMTHRLIRPWLIFDWIYKLTSTGQQEKKQSQDLSA 256 Query: 204 LTNKVIKNKK 213 +++I+ K+ Sbjct: 257 ACHRIIQEKR 266 >UniRef50_Q16I47 Cluster: Cytochrome P450; n=7; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 506 Score = 166 bits (403), Expect = 1e-39 Identities = 87/241 (36%), Positives = 138/241 (57%), Gaps = 6/241 (2%) Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319 D +EN + K+++ FLDL++ + NG +S +I+EEVDT MFEGHDTT +G SF L Sbjct: 269 DLQEEN-MYTKRKMTFLDLLLNVTVNG-KPLSREDIREEVDTFMFEGHDTTTSGISFTLW 326 Query: 320 LLGIHQDVQARVYDELYQIFGDSDRPA--TFADTLEMKYLERVILESLRLYPPVPVIARK 377 L +QDVQ ++++E+ ++ G A T E+ YL+ V+ ESLRL PPVP+I R Sbjct: 327 HLAKYQDVQQKLFEEIDRVLGKDKVNAELTNLQIQELDYLDMVVKESLRLIPPVPIIGRT 386 Query: 378 LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIP 437 L D+ ++ IPAGT + I + +HR PK ++ + F P+ F N R Y +IP Sbjct: 387 LVEDMEMN--GVTIPAGTQISIKIYNIHRNPKIWEKSDEFIPERFSKTNESKRGPYDFIP 444 Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 FSAG R+C+G++YA +F+ + + + + D++++ G +K+ Sbjct: 445 FSAGSRNCIGQRYAMMELKVTIIKLIASFKVLPGDSMDKLRFKTDLVIRPDNGIPIKLVE 504 Query: 498 R 498 R Sbjct: 505 R 505 Score = 135 bits (327), Expect = 2e-30 Identities = 70/196 (35%), Positives = 118/196 (60%), Gaps = 2/196 (1%) Query: 37 SKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFH 96 ++L++ L + ++E +L + I K+ Y F +PWLG GLLIS+G KW RK+I PTFH Sbjct: 78 NELVMDLSSSKNVEKVLLAK-SIKKSFAYDFLEPWLGTGLLISTGEKWFQRRKIITPTFH 136 Query: 97 INILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRKTQDES 155 ++L+ F+ +FN+ +N +V KLK++ GK FD++DY++ +D + ET+MG+ QD+ Sbjct: 137 FSMLEGFLEVFNKEANILVSKLKAKAGKDEFDIYDYVTLYALDSICETSMGVQINAQDDP 196 Query: 156 GFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKET 215 +YA+AV +M I +R + +F L F K+Q K++ +H TN VI ++ Sbjct: 197 NNEYAVAVKQMSTFILRRVFSILRTFPSLFFLYPFAKEQKKVILKLHNFTNSVIDARRAM 256 Query: 216 YLENKAKGIIPPTLEE 231 + K+ + L+E Sbjct: 257 LEKEKSNKNVTFDLQE 272 >UniRef50_Q170T3 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 497 Score = 165 bits (401), Expect = 2e-39 Identities = 86/224 (38%), Positives = 131/224 (58%), Gaps = 7/224 (3%) Query: 248 SDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGH 307 +D V R+ L +DE G KK+ AFLD+++ +S NG +++ EI+EEVDT MFEGH Sbjct: 277 TDNVIVSRRNQLMISDE--FGAKKKDAFLDMLLRTSING-KPLTNLEIREEVDTFMFEGH 333 Query: 308 DTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLR 366 DTT + F L L H ++Q +VYDE+ + G D + ++ Y E I E+LR Sbjct: 334 DTTTSAVVFTLFNLAKHPEIQQKVYDEIVSVIGKDPKEKIELSHLHDLSYTEMAIKETLR 393 Query: 367 LYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPE- 425 L+P VP+I R+ ++TI K IPAG +++G + + R KY+++P F P+ F E Sbjct: 394 LFPSVPLIGRRCVEEITIEGK--TIPAGANIIVGIYFMGRDTKYFENPSQFIPERFEGEF 451 Query: 426 NTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTI 469 + + + Y YIPFSAGPR+C+G+K+A R++ I Sbjct: 452 SVEKFNPYKYIPFSAGPRNCIGQKFALNEMKSVISKLLRHYEFI 495 Score = 97.1 bits (231), Expect = 1e-18 Identities = 53/166 (31%), Positives = 94/166 (56%), Gaps = 5/166 (3%) Query: 51 IILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQN 110 I+ N H+ DK+ EY + WLG+GLL+S KW + RK I P FH IL+ FV +F++N Sbjct: 122 ILTNKHL-TDKSGEYDYLSNWLGDGLLLSKRHKWHARRKAITPAFHFKILEQFVDVFDRN 180 Query: 111 SNNVVEKLK--SEVGKTFDVHDYMSGTTVDILL-ETAMGISRKTQDESGFDYAMAVMKMC 167 + +V+ L+ ++ GKTFD+ Y+ +D++ E G K + E+ ++ + Sbjct: 181 AAELVDVLEKHADDGKTFDMFPYVLLYALDVICGELGTGCKLKRKHENLDNFRKCNGNIT 240 Query: 168 DIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213 + +R + R+ + F LT +++ K L ++HG T+ VI +++ Sbjct: 241 HVSIKRMFDIIRRTSL-FYLTPSYQKLRKALKVLHGYTDNVIVSRR 285 >UniRef50_Q17PE3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 513 Score = 164 bits (398), Expect = 6e-39 Identities = 125/458 (27%), Positives = 222/458 (48%), Gaps = 43/458 (9%) Query: 35 LGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPT 94 LG + + + D + +L+ ++K Y F + L G+ + W+ RK + PT Sbjct: 77 LGPIMGIGISHPDLMHKVLSHPDCLEKPFFYNFVQ--LEHGIFSAEYKLWKGQRKALNPT 134 Query: 95 FHINILKSFVGIFNQNSNNVVEKL-KSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQD 153 F++ IL SF+ IF S+ +V L K G+T D+ + S T++++ T +G S + Sbjct: 135 FNMKILNSFISIFEDCSSRMVADLFKCANGETVDMFQFTSKCTLEMVCATTLG-SNVLER 193 Query: 154 ESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213 E ++ + + +++ +R + + +++LTS+++++ K I+ K Sbjct: 194 EGSDEFLRNMEGLFELVGKRMLSVELFLDSIYRLTSYYRKEMK------------IRKKI 241 Query: 214 ETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRL 273 E + N II E + +NA T + DE+D+ +K Sbjct: 242 EEFSGN----IIREKRREHMFCLNQQHLHNASTPKE-------------DEDDI--RKPQ 282 Query: 274 AFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYD 333 F+D ++ S N + +D EI V TIM G+DT+ G + L I+ ++Q +VYD Sbjct: 283 IFIDQLLSLS-NSSRPFTDEEILHNVLTIMIAGNDTSGLGVAHACLFLAIYPNIQQKVYD 341 Query: 334 ELYQIF---GDSDRPATFADTL-EMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389 E+ + F G +DR + AD L +++Y E + E LR P P +AR+ +++ + Sbjct: 342 EVMKHFPPDGPNDRISLDADFLRQLEYTEMFLKEVLRHCPVAPTVARQNLKELELDGVR- 400 Query: 390 VIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 IPAG T+ F LHR+ + D E F+P+NF PE + RH Y+++PFS+G R+C+G Sbjct: 401 -IPAGNTLSFSFFALHRRKDIWGPDAEKFDPENFAPERCEKRHPYAFMPFSSGSRNCIGG 459 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486 +YA RNF + + + + + LK Sbjct: 460 RYAMISMKVMIVYIVRNFSLKTNLRHSHLRYKFGMTLK 497 >UniRef50_Q16P39 Cluster: Cytochrome P450; n=7; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 504 Score = 164 bits (398), Expect = 6e-39 Identities = 79/244 (32%), Positives = 140/244 (57%), Gaps = 4/244 (1%) Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSS 315 ++D+DF E + G++ F++ +++ + + S + +D +F G+DT+A Sbjct: 264 KEDIDFKTE-ETGKRIPENFIECLVKYLR-AEGETSKDAVYPHIDMTVFAGNDTSAKTIC 321 Query: 316 FVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIA 375 +L +L +H +VQ R Y EL ++ + D+ ++ D + YLE V E++RL P VP +A Sbjct: 322 SILLMLAMHPEVQERCYQELMEVCPEKDQHISYKDAANLTYLEMVCKETMRLLPAVPFMA 381 Query: 376 RKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYS 434 R + D+ ++ + + IPA T+++G F +HR P+ + + + F+PDNFLP+N RH YS Sbjct: 382 RITSGDIVLNDQ-HTIPANCTIIMGIFQIHRDPRIWGPNADNFDPDNFLPDNVAKRHPYS 440 Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMK 494 YIPFSAGPR+C+G +YA R +R + + + ++ ++L + G QM Sbjct: 441 YIPFSAGPRNCIGTRYAYLSSKIMVGSILRKYRLKTSLTMDKLRISCGLLLHISNGCQMA 500 Query: 495 VEPR 498 +E R Sbjct: 501 IEHR 504 Score = 76.2 bits (179), Expect = 2e-12 Identities = 53/204 (25%), Positives = 100/204 (49%), Gaps = 11/204 (5%) Query: 13 TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72 T K + L Y F + + + +G V + D + ++++L+S +DK+ +Y F + + Sbjct: 55 TPKAIAGTLKYFSKFPSPVCIHMGPLPHVAIFDPEQLQVVLHSQNCLDKSVQYSFLR--V 112 Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDY 131 E L+ + G W+ RK + P+F IL +F IFN + ++L+ GK + + Sbjct: 113 SETLISAPGHLWKGQRKALNPSFGPAILTTFAEIFNNKCAILTKRLEEYAGKPERNFYRD 172 Query: 132 MSGTTVDILLETAMGISRKTQ----DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKL 187 +S T+D + TA G Q E D A MK ++ R + W E +++ Sbjct: 173 ISKCTLDQIYATAFGCDFNMQTSLDGERSLDLQEAYMK---VMANRFFSVWKYPEFIYRW 229 Query: 188 TSFFKQQTKLLGIIH-GLTNKVIK 210 T+ +K++ +L I H +T K+++ Sbjct: 230 TAGYKKELELRRIYHETITCKLVQ 253 >UniRef50_Q9V7G5 Cluster: Probable cytochrome P450 4aa1; n=5; Diptera|Rep: Probable cytochrome P450 4aa1 - Drosophila melanogaster (Fruit fly) Length = 514 Score = 164 bits (398), Expect = 6e-39 Identities = 91/257 (35%), Positives = 138/257 (53%), Gaps = 4/257 (1%) Query: 242 NNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDT 301 N K L+D K + + N+ G +R LD MIE S++ + ++ +I E T Sbjct: 255 NQKKRLNDFTRKMIQRRRQIQNNNN-GNSERKCLLDHMIEISESNRD-FTEEDIVNEACT 312 Query: 302 IMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVI 361 M G D+ A +F L LL + + Q R EL IF DS+R T D EM+Y+E I Sbjct: 313 FMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCI 372 Query: 362 LESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDN 421 E+LRLYP VP+IARKL +V ++ + +PAG+ V I + HR Y DPE F P+ Sbjct: 373 KEALRLYPSVPLIARKLGEEVRLA--KHTLPAGSNVFICPYATHRLAHIYPDPEKFQPER 430 Query: 422 FLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQG 481 F PEN++NRH Y+++PFSAGPR C+G ++A R+++ + + Sbjct: 431 FSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATF 490 Query: 482 DIILKRAEGFQMKVEPR 498 I L+ + G ++++ R Sbjct: 491 RITLRASGGLWVRLKER 507 Score = 98.7 bits (235), Expect = 3e-19 Identities = 51/195 (26%), Positives = 103/195 (52%), Gaps = 2/195 (1%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86 +G+++R+W+ +++ +D+++IL+S H +K YR +LG+GL+ SSG KW + Sbjct: 84 YGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLGDGLITSSGSKWSN 143 Query: 87 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSE-VGKTFDVHDYMSGTTVDILLETAM 145 HR++I P FH N+L+ F+ F S ++ E L +E VG ++ Y++ +DIL E + Sbjct: 144 HRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIAKYVNNCVLDILNEAVL 203 Query: 146 GISRKTQDESGFDYAMAVMKMCDI-IHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGL 204 G+ K + + + + I + R + W+ + ++ T + ++ Sbjct: 204 GVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMANDELNQKKRLNDF 263 Query: 205 TNKVIKNKKETYLEN 219 T K+I+ +++ N Sbjct: 264 TRKMIQRRRQIQNNN 278 >UniRef50_Q9XVA6 Cluster: Putative uncharacterized protein cyp-37A1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein cyp-37A1 - Caenorhabditis elegans Length = 508 Score = 163 bits (396), Expect = 1e-38 Identities = 85/232 (36%), Positives = 133/232 (57%), Gaps = 4/232 (1%) Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328 E K+ AFLD++IE + G + +I+EEVDT MFEGHDTT+AG + L L + Q Sbjct: 281 ESKKKAFLDMLIEKKEEGG--LGYEDIREEVDTFMFEGHDTTSAGIGWSLWCLANCPEYQ 338 Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 + ++EL +IF + R + D +MKYLE+ + E+LR+ P VP +AR + +V I K Sbjct: 339 KKCHEELDEIFEGTSRECSVEDLKKMKYLEKCVKEALRMRPSVPQMARSVEEEVEIDGK- 397 Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 ++P G +V+I + P+ + + EVF+P+ F + RH Y+YIPFSAGPR+C+G+ Sbjct: 398 -ILPKGCSVMISPAFIQNNPRTFPNHEVFDPERFNEDEISKRHAYAYIPFSAGPRNCIGQ 456 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500 K+A R F ++I E + I + + GF +K R++ Sbjct: 457 KFAMQEEKTVISWVLRRFHIHTDIGLLENMPLPETITRPSLGFPLKFTVRQQ 508 Score = 118 bits (285), Expect = 3e-25 Identities = 65/215 (30%), Positives = 110/215 (51%), Gaps = 4/215 (1%) Query: 15 KLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGE 74 +L N L Y+ ++ W+G +V ++ + + +L S+ I+K++EY F PWLG Sbjct: 64 QLYNWGLEYSTKGSSLAAFWMGPYPMVIVLTPEANKKVLESNALINKSSEYDIFLPWLGT 123 Query: 75 GLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK----TFDVHD 130 GLL++SG KWR RKM+ P+FH N+L F +FN S ++E++++ K T D Sbjct: 124 GLLLASGEKWRGRRKMMTPSFHFNVLIDFQVVFNSQSMILLEQIENAAKKTDDSTIDAFP 183 Query: 131 YMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSF 190 Y+ +DI+ ETAMG + Q Y +AV +M + + W+ + + +L + Sbjct: 184 YIKRCALDIICETAMGTTVSAQTNHTHPYVVAVNEMNSLAFKYQRMPWLWIKPIRQLIGY 243 Query: 191 FKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGII 225 + L I+ T KVI K + E ++ Sbjct: 244 EADFQRNLDIVTSFTKKVIDRKLREHDETDGMVVV 278 >UniRef50_Q9V558 Cluster: Cytochrome P450 4p1; n=5; Sophophora|Rep: Cytochrome P450 4p1 - Drosophila melanogaster (Fruit fly) Length = 513 Score = 163 bits (396), Expect = 1e-38 Identities = 89/264 (33%), Positives = 140/264 (53%), Gaps = 9/264 (3%) Query: 236 SGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDH-E 294 S EI+A L D + K D++ KKR A LD +I + ++G + DH Sbjct: 257 SSEIIAKRRDLLKDELDKSSSTA----DDDGFVSKKRFAMLDTLIYAEKDG---LIDHIG 309 Query: 295 IKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEM 354 I EEVDT+MFEG+DTT+ G F L + ++ D Q Y E+ + D ++ Sbjct: 310 ICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHIDDDLSNLDVGQLNKL 369 Query: 355 KYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDP 414 KYLE + E+ RL+P VP++ R+ ++ ++ ++P G + I F +HR KY+ P Sbjct: 370 KYLEYFMKETTRLFPSVPIMGREAVQETELAN-GLILPKGAQITIHVFDIHRNAKYWDSP 428 Query: 415 EVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPE 474 E F P+ FLPEN Q+RH Y+Y+PFSAG R+C+G+KYA + F+ + I Sbjct: 429 EEFRPERFLPENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKVLKAIDP 488 Query: 475 KEFKLQGDIILKRAEGFQMKVEPR 498 ++ I L+ + ++K+ R Sbjct: 489 QKIVFHTGITLRTQDKIRVKLVRR 512 Score = 95.9 bits (228), Expect = 2e-18 Identities = 55/191 (28%), Positives = 94/191 (49%), Gaps = 1/191 (0%) Query: 24 AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK 83 A+ G ++ K I ++DAD E +LN I K Y F P+L GLL S+G K Sbjct: 77 AKEMGTSYIEYVFGKAIYNIIDADSAENVLNHPNLITKGLVYNFLHPFLRTGLLTSTGKK 136 Query: 84 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLET 143 W + RKM+ PTFH NIL F IF S + + + + T +HD + T++ + ET Sbjct: 137 WHARRKMLTPTFHFNILNQFQEIFKTESQKFLLQFEGQDEVTITLHDVIPRFTLNSICET 196 Query: 144 AMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHG 203 AMG+ E G Y ++ + +R + + +F++ + K L ++H Sbjct: 197 AMGVKLDEMAEKGDRYRENFSQIEECFIRRLSNPLLWGDKLFEMFA-AKDFASALDVVHR 255 Query: 204 LTNKVIKNKKE 214 ++++I +++ Sbjct: 256 FSSEIIAKRRD 266 >UniRef50_Q9N525 Cluster: Cytochrome p450 family protein 29A3; n=6; Caenorhabditis|Rep: Cytochrome p450 family protein 29A3 - Caenorhabditis elegans Length = 503 Score = 163 bits (395), Expect = 1e-38 Identities = 80/227 (35%), Positives = 126/227 (55%), Gaps = 5/227 (2%) Query: 242 NNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDT 301 N KT + V R + + K+ + FLD+++ + ++ +S ++++EVDT Sbjct: 249 NIMKTFTRNVIAERRTARESGEVEKETSKRNMNFLDILLSNEESSV--LSPEDLRQEVDT 306 Query: 302 IMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERV 360 MF GHDTT S+V L H D+Q VY+E+ +FG D + T +++Y ER+ Sbjct: 307 FMFAGHDTTTTSVSWVCWNLAHHPDIQQNVYEEIVSVFGEDPNEDVTTEGIKKLEYTERM 366 Query: 361 ILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPD 420 + ES R+ P VP + R+L D+ I +IPAG V I +H+ Y++P++F+PD Sbjct: 367 LKESKRICPTVPAVLRQLISDMEIG--GVLIPAGANVAIAPMAIHKNANIYQNPDIFDPD 424 Query: 421 NFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467 FLPE T RH Y +IPFSAG R+C+G+K+A +NF+ Sbjct: 425 RFLPEETAKRHAYDFIPFSAGLRNCIGQKFAQLNEKVMVIHLLKNFK 471 Score = 91.1 bits (216), Expect = 6e-17 Identities = 52/157 (33%), Positives = 80/157 (50%), Gaps = 3/157 (1%) Query: 10 ENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFK 69 E + Q L +L + ++IR + V+ +D + IL S +DK Y FF Sbjct: 57 EEIFQALRDLFSEAVEKGQSLIRHRILGTFYVWPLDGKTVSKILESTTELDKGGPYEFFN 116 Query: 70 PWLGEGLLISS-GPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTF 126 WLG G L+ G +WRSHRKM+ PTFH L+ + +FN S VV+ L ++ G+T Sbjct: 117 DWLGGGTLLEGYGERWRSHRKMLTPTFHFAKLEGYFEVFNTESRVVVDCLDKFAKSGETV 176 Query: 127 DVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAV 163 D+ + T+D + +TAMG Q ++ Y A+ Sbjct: 177 DLFPFFKRCTLDTICKTAMGAKVDAQLQNSHPYITAI 213 >UniRef50_Q16E69 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 348 Score = 162 bits (393), Expect = 2e-38 Identities = 80/192 (41%), Positives = 119/192 (61%), Gaps = 8/192 (4%) Query: 260 DFNDEND-VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318 DF++EN V +R A LD ++ S N+I + I+EEVDT MFEGHDTTA+ +F+ Sbjct: 155 DFSEENIYVNTNQRYALLDTLLASEAK--NQIDEEGIREEVDTFMFEGHDTTASAFTFIF 212 Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPA---TFADTLEMKYLERVILESLRLYPPVPVIA 375 ++ HQ+ Q ++ +E+ + +P + D E+K+++RVI E LRLYPPVP I+ Sbjct: 213 LVIANHQEAQRQLVEEIEAMIAGRIKPTEPLSMHDYSELKFMDRVIKECLRLYPPVPFIS 272 Query: 376 RKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSY 435 R + D + + IP + + F LHR P + DPE F+PD FLP N + R+ Y+Y Sbjct: 273 RAILEDALLGDR--FIPKDSMANLHIFDLHRDPDQFPDPERFDPDRFLPANVEKRNPYAY 330 Query: 436 IPFSAGPRSCVG 447 +PFSAGPR+C+G Sbjct: 331 VPFSAGPRNCIG 342 Score = 41.1 bits (92), Expect = 0.067 Identities = 35/158 (22%), Positives = 72/158 (45%), Gaps = 12/158 (7%) Query: 141 LETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGI 200 +ETAMG+ + + +Y + ++ ++ R W+ E ++L F ++ K+L Sbjct: 72 IETAMGVKLDSMSMAD-EYRAKIQEVIKLLLLRVMNPWLVEEFPYRLLGFRRRLMKVLKP 130 Query: 201 IHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGE-------ILANNAKTLSDTVFK 253 IH T +IK +++ + N K + + E ++ + +LA+ AK D + Sbjct: 131 IHAFTRSIIKQRRDLFHAN-VKNVDDFSEENIYVNTNQRYALLDTLLASEAKNQIDE--E 187 Query: 254 GYRDDLD-FNDENDVGEKKRLAFLDLMIESSQNGTNKI 290 G R+++D F E F+ L+I + Q ++ Sbjct: 188 GIREEVDTFMFEGHDTTASAFTFIFLVIANHQEAQRQL 225 >UniRef50_A1BPR9 Cluster: CYP4BD1; n=1; Ips paraconfusus|Rep: CYP4BD1 - Ips paraconfusus Length = 504 Score = 160 bits (388), Expect = 9e-38 Identities = 86/233 (36%), Positives = 132/233 (56%), Gaps = 5/233 (2%) Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327 G + RLAFLDL++E+ +GT ++ E+++EV+T MFEGHDTT++ +F L +L H V Sbjct: 275 GIRTRLAFLDLLLEAKIDGT-PLTKAELRDEVNTFMFEGHDTTSSAITFCLLMLATHPRV 333 Query: 328 QARVYDELYQIFGDSDRPA--TFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIS 385 Q +V E +I + A T + +MKYLE VI E+LRLYP VP+ +RKL DV Sbjct: 334 QDKVMAEQKEILEGDLKLAHPTSKELSQMKYLENVIKETLRLYPSVPLFSRKLGEDVEF- 392 Query: 386 TKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSC 445 K + P G T+V+ + HR P + +PE F P+ F + ++Y PFSAG R+C Sbjct: 393 -KGNLYPKGITLVLTPYATHRDPDIFPEPEKFLPERFEESEMLKINPFAYTPFSAGSRNC 451 Query: 446 VGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 +G+K+A R+F+ PE + +L + L G ++ ++ R Sbjct: 452 IGQKFAMMEIKSTVSKVVRHFKLEPAHPEHQIQLVSETTLNSKNGVKISLQAR 504 Score = 134 bits (324), Expect = 5e-30 Identities = 68/177 (38%), Positives = 104/177 (58%), Gaps = 6/177 (3%) Query: 40 IVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 99 +V D + IE+I +S HI K ++Y +FK WLG+GLLIS G KWR HRK+I PTFH +I Sbjct: 83 VVITADPEFIELIYSSSTHITKGSQYDYFKRWLGQGLLISDGDKWRFHRKIITPTFHFSI 142 Query: 100 LKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHDYMSGTTVDILLETAMGISRKT---QDES 155 L+ F+ +F+ +N V KL+ VG T ++ + +S T+DI+ ETAMG+ +D Sbjct: 143 LQQFLTVFDTVGDNFVRKLQQHVGSTSVEISNLISLCTLDIICETAMGVKMNALDMKDSE 202 Query: 156 GFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNK 212 +Y + MC II R + F I + LT + ++ + L +++G + VI K Sbjct: 203 NMEYIKGIRIMCKIIVDRMFSF--LHPIFYPLTLNYYREKRALKMVNGYVDNVISQK 257 >UniRef50_UPI0000D5646A Cluster: PREDICTED: similar to CYtochrome P450 family member (cyp-31A3); n=2; Tribolium castaneum|Rep: PREDICTED: similar to CYtochrome P450 family member (cyp-31A3) - Tribolium castaneum Length = 349 Score = 159 bits (387), Expect = 1e-37 Identities = 88/259 (33%), Positives = 146/259 (56%), Gaps = 8/259 (3%) Query: 242 NNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDT 301 N K D + K +R D +N+ EK+ L+ +++ S+ KI +++E+ T Sbjct: 97 NCGKDSFDILPKLFRCTFDTACDNNHREKR---LLNHLLKLSKINA-KIDQTALEDEIQT 152 Query: 302 IMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVI 361 I+ G +TTA L +LGI+ ++Q ++ EL IFG DR T D M+YLERVI Sbjct: 153 ILLTGSETTALTVGLTLIILGIYPEIQKKIGKELDVIFGKDDRVPTLEDINRMEYLERVI 212 Query: 362 LESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDN 421 E+LR PVP + R N+D+T+ + IPAG+ ++I F +H++P+Y+K+P F+PD Sbjct: 213 KETLRFLTPVPFMLRTNNQDITLDSN--TIPAGSCIMIPIFHIHKKPEYWKNPNEFDPDR 270 Query: 422 FLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEK--EFKL 479 FLPEN+ R ++IPFS+GPR+C+G KY R + ++ +K + ++ Sbjct: 271 FLPENSSKRPRCAFIPFSSGPRNCIGFKYGMMSVKVLLAVILRKYTVVATEYKKVEDIEM 330 Query: 480 QGDIILKRAEGFQMKVEPR 498 ++ K G ++K+E + Sbjct: 331 LFYVVNKPISGCKIKLEKK 349 Score = 46.8 bits (106), Expect = 0.001 Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 4/73 (5%) Query: 70 PWLGEGLLISSGPK---WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-T 125 P G + G K W+S RKMI PTF+ NIL SFV IF +++ + L+ GK + Sbjct: 43 PIFGSAHYLMGGHKVDVWKSRRKMINPTFNPNILNSFVEIFGRHAFYLTNALEENCGKDS 102 Query: 126 FDVHDYMSGTTVD 138 FD+ + T D Sbjct: 103 FDILPKLFRCTFD 115 >UniRef50_Q27606 Cluster: Cytochrome P450 4e2; n=11; Diptera|Rep: Cytochrome P450 4e2 - Drosophila melanogaster (Fruit fly) Length = 526 Score = 157 bits (382), Expect = 5e-37 Identities = 81/207 (39%), Positives = 121/207 (58%), Gaps = 8/207 (3%) Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329 +K++AFLD ++ S+ +G ++ E+ EEV T MFEGHDTT +G SF + LL HQD Q Sbjct: 273 RKKMAFLDTLLSSTIDG-RPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQR 331 Query: 330 RVYDELYQIFGDSD--RPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387 +++ E ++ G+S+ R ATF + +MKYL+ I E+ R+YP VP I R +D I Sbjct: 332 KLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVID-- 389 Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447 ++P GTT+ +G ML K +KDP F P+ F + + Y+PFSAGPR+C+G Sbjct: 390 GDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF---ELEKPGPFEYVPFSAGPRNCIG 446 Query: 448 RKYAXXXXXXXXXXXXRNFRTISEIPE 474 +K+A RNF + + E Sbjct: 447 QKFALLEIKTVVSKIIRNFEVLPALDE 473 Score = 122 bits (294), Expect = 2e-26 Identities = 69/232 (29%), Positives = 115/232 (49%), Gaps = 5/232 (2%) Query: 4 NIHVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKAT 63 N H +N ++ L + + Q + W+G+ V + + +E IL+S I K+ Sbjct: 44 NAHQMGKNPSEILDTVFSWWHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSD 103 Query: 64 EYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG 123 Y+ PWLG GLL S+G KW HRKMI P FH NIL+ F + N+NS ++ LK+ Sbjct: 104 IYQLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAA 163 Query: 124 --KTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRS 181 FD + T+D++ +TAMG+S + A MC I+ R + R+ Sbjct: 164 GDNIFDFQEQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRN 223 Query: 182 EIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFT 233 E++++L + ++ L + TN++I + E + K+ + +EFT Sbjct: 224 ELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRIEAH---KSGAVSTNAGDEFT 272 >UniRef50_A1BPS3 Cluster: CYP4BG1; n=1; Ips paraconfusus|Rep: CYP4BG1 - Ips paraconfusus Length = 498 Score = 157 bits (380), Expect = 9e-37 Identities = 89/229 (38%), Positives = 125/229 (54%), Gaps = 8/229 (3%) Query: 270 KKRLAFLDLMI-ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328 +K LDL++ E Q G+ I I+EEVDT MFEGHDTT+A F+L L + +Q Sbjct: 275 RKIYKMLDLLLHEKLQFGS--IDYEGIREEVDTFMFEGHDTTSAALVFLLHNLASNLAIQ 332 Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 +V E+ + +R TF + Y +RVI ESLRLYP VP I+R + D T Sbjct: 333 EKVRQEIKTV----ERIPTFQTLQNLPYTDRVIKESLRLYPSVPFISRIASEDFITHT-G 387 Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 Y I GT + + F LHR P+ Y DP F+PD FLPE + RH ++Y+PFSAGPR+C+G+ Sbjct: 388 YSISKGTVLYMHIFDLHRNPEIYPDPLTFDPDRFLPEKVKERHPFAYLPFSAGPRNCIGQ 447 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 K+A FR + + Q D+IL+ ++ +P Sbjct: 448 KFAMLELKAVLWGLLHKFRLTLDPSTTQINFQVDLILRTQGEIKINFQP 496 Score = 116 bits (278), Expect = 2e-24 Identities = 76/288 (26%), Positives = 143/288 (49%), Gaps = 15/288 (5%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82 +A+ +G + R+ + IV D+EIIL+ H+ K+ Y+F + WLG+GLL S+G Sbjct: 62 FARDYGPIYRISIPFLDIVNFFHPADLEIILSQKKHMKKSLLYQFLEGWLGKGLLTSTGS 121 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT------FDVHDYMSGTT 136 KW+ RK++ FH NIL+ FV +FN+ + ++V++++ E+ T V ++ T Sbjct: 122 KWQFRRKLLTQAFHFNILQKFVRVFNEETTHLVKRIE-EINLTGQSQAGISVLPLITHLT 180 Query: 137 VDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTK 196 + + ET++G+S + E+ Y + KM D + R K W ++ T KQ+ Sbjct: 181 LQSVTETSLGVS-NIEKETLKAYRENIYKMGDFLIDRLRKPWRLFNFIYHFTEASKQEQL 239 Query: 197 LLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLE-EFTHHSGEILANNAKTLSDTVFKGY 255 + +H T +VIK ++E +K + ++ T + ++L + ++G Sbjct: 240 TINKLHQFTYQVIKEREEVLQSDKTQSVMTSTYSGRKIYKMLDLLLHEKLQFGSIDYEGI 299 Query: 256 RDDLD-FNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTI 302 R+++D F E L FL + S N ++++E+ T+ Sbjct: 300 REEVDTFMFEGHDTTSAALVFLLHNLAS-----NLAIQEKVRQEIKTV 342 >UniRef50_P33269 Cluster: Cytochrome P450 4d1; n=11; Diptera|Rep: Cytochrome P450 4d1 - Drosophila melanogaster (Fruit fly) Length = 512 Score = 157 bits (380), Expect = 9e-37 Identities = 81/241 (33%), Positives = 139/241 (57%), Gaps = 8/241 (3%) Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321 ND+ DVG K+++AFLD++++S+ + +S+ +I+EEVDT MFEGHDTT++ F + Sbjct: 274 NDDADVGAKRKMAFLDILLQSTVD-ERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNI 332 Query: 322 GIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380 H + Q + ++E+ + G D P ++ ++ Y++ + E+LR+YP VP++ RK+ Sbjct: 333 ATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLE 392 Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNF-LPENTQNRHYYSYIPFS 439 D I+ K +IPAGT + I L R+ + + +P F P+ F + + + Y+YIPFS Sbjct: 393 DCEINGK--LIPAGTNIGISPLYLGRREELFSEPNSFKPERFDVVTTAEKLNPYAYIPFS 450 Query: 440 AGPRSCVGRKYAXXXXXXXXXXXXRNFRT--ISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 AGPR+C+G+K+A R++ + + E L ++IL+ E KV Sbjct: 451 AGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPV-LIAELILRTKEPLMFKVRE 509 Query: 498 R 498 R Sbjct: 510 R 510 Score = 141 bits (342), Expect = 3e-32 Identities = 67/206 (32%), Positives = 118/206 (57%), Gaps = 6/206 (2%) Query: 15 KLVNLALGYAQTFGN--VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72 ++V + +T+ V++VWLG +L V + + D+E++L + DKA EY+ +PWL Sbjct: 56 EMVKKIFEFMETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWL 115 Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK----TFDV 128 EGLL+S G KW RK+I P FH IL FV +F + S +++ ++ + K F + Sbjct: 116 KEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGESGFSL 175 Query: 129 HDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLT 188 +D+++ T+D + ETAMG+S Q + +Y AV + ++H+R + R ++ + LT Sbjct: 176 YDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLT 235 Query: 189 SFFKQQTKLLGIIHGLTNKVIKNKKE 214 + + K L ++H T K+I ++E Sbjct: 236 PLARAEKKALNVLHQFTEKIIVQRRE 261 >UniRef50_O46054 Cluster: Cytochrome P450 4ae1; n=1; Drosophila melanogaster|Rep: Cytochrome P450 4ae1 - Drosophila melanogaster (Fruit fly) Length = 496 Score = 157 bits (380), Expect = 9e-37 Identities = 85/226 (37%), Positives = 131/226 (57%), Gaps = 6/226 (2%) Query: 274 AFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYD 333 A LD ++ ++ +G ++D +I++EV+T +FEGHDTT + SF L LL H+ VQ ++++ Sbjct: 274 ALLDTLLRATVDG-QPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFE 332 Query: 334 ELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIP 392 EL +G D R +D + YL V+ ESLRLYPP+P +AR L +D+ I + Y IP Sbjct: 333 ELRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLEKDLVID-EGY-IP 390 Query: 393 AGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 452 GT VV+ + L R + DP VF P+ L E YSYIPFSAGPR+C+G+K+A Sbjct: 391 VGTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFAL 450 Query: 453 XXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 R+++ + + E ++ I+L+ G + + PR Sbjct: 451 LEMKTMVTKVIRHYQLLPMGADVEPSIK--IVLRSKSGVNVGLRPR 494 Score = 97.1 bits (231), Expect = 1e-18 Identities = 60/211 (28%), Positives = 110/211 (52%), Gaps = 11/211 (5%) Query: 8 QEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRF 67 Q +NL K Y + FG + +++ + I+ +L + K T Y Sbjct: 53 QPDNLHDKFAE----YVKRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQHQLKKGTMYFA 108 Query: 68 FKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKT 125 + WLG+GLL+S G +W + RK+I PTFH +IL+ FV +F++ S+ +VE+L+ S + Sbjct: 109 LRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEV 168 Query: 126 FDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVF 185 +++ + +DI+ ETAMG++ Q + AV + +I+ R + + +F Sbjct: 169 VNIYPLVGLAALDIITETAMGVNVDAQGADS-EVVHAVKDLTNILATRFMRPHLLFPHLF 227 Query: 186 KL---TSFFKQQTKLLGIIHGLTNKVIKNKK 213 +L + F KQQ ++ +H TN +I+ ++ Sbjct: 228 RLCWPSGFRKQQAGVI-CLHEFTNGIIEQRR 257 >UniRef50_Q9VLZ7 Cluster: Probable cytochrome P450 4d21; n=5; Sophophora|Rep: Probable cytochrome P450 4d21 - Drosophila melanogaster (Fruit fly) Length = 511 Score = 156 bits (379), Expect = 1e-36 Identities = 80/240 (33%), Positives = 138/240 (57%), Gaps = 7/240 (2%) Query: 264 ENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323 ++D+G K ++ LD++++++ + +SD +I+EEVD +F G DTT +G S L + Sbjct: 276 DDDIGGKAKMTLLDILLQATIDN-KPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISR 334 Query: 324 HQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382 H VQ +Y+EL + G D D T LE+KYL+ VI E++RL+PPVP++ R + D+ Sbjct: 335 HPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDL 394 Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP-ENTQNRHYYSYIPFSAG 441 I IP T++++ + ++R P+Y+ DP VF P+ ++ + T N +YIPFS+G Sbjct: 395 KIG--EITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSG 452 Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRV 501 P++C+G+K+A R++ + + K IL + G + ++PR RV Sbjct: 453 PKNCIGQKFANLQMKALISKVIRHYELLP--LGADLKATYTFILSSSTGNNVGLKPRTRV 510 Score = 130 bits (313), Expect = 1e-28 Identities = 80/250 (32%), Positives = 129/250 (51%), Gaps = 5/250 (2%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82 Y +G R+W+ + +++ D E IL+S + KA YRF + +LG+GLL+S+G Sbjct: 63 YFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLSTGN 122 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKT-FDVHDYMSGTTVDIL 140 KW S RK++AP FH L++FV I ++NS +VEKLK+ GKT D+ ++S +D+ Sbjct: 123 KWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVT 182 Query: 141 LETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTS--FFKQQTKLL 198 ETAMG+ Q+E F Y A+ + I +R MR +F L + +++ K + Sbjct: 183 TETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDI 242 Query: 199 GIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAK-TLSDTVFKGYRD 257 I+ T+KVI+ ++ +A G P + G+ L T+ Sbjct: 243 AIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNKPLS 302 Query: 258 DLDFNDENDV 267 D+D +E DV Sbjct: 303 DVDIREEVDV 312 >UniRef50_UPI00015B5723 Cluster: PREDICTED: similar to cytochrome P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 523 Score = 155 bits (377), Expect = 2e-36 Identities = 83/228 (36%), Positives = 128/228 (56%), Gaps = 5/228 (2%) Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328 ++ RL L+ +I+ + TN ++D E+++E TI DTT SSF L L I+Q++Q Sbjct: 299 DRPRLMLLEQLIDHNAK-TNLMNDTELRDETYTIFTAAQDTTGVISSFALLNLAINQEIQ 357 Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 +V +E+ + G+ T E+KY E VI E+LRLYP P++ R+ D+ + T Sbjct: 358 DKVREEIRNVVGNDS--VTVEHLPELKYTELVIKETLRLYPIAPLMVREATGDIDLET-- 413 Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 +P G ++V+ + HR KY+ DPE F P+ FLPEN+ RH Y+YIPFS G R CVG+ Sbjct: 414 CTLPKGCSIVMIPYETHRSTKYWTDPEKFIPERFLPENSVGRHPYAYIPFSGGLRGCVGQ 473 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496 K+A R R S + +L+ DI ++ +G+ + VE Sbjct: 474 KFAIMCLKTMLVHVIRKVRLTSTQNLETLRLKADISVRSRDGYMVSVE 521 Score = 117 bits (282), Expect = 6e-25 Identities = 68/235 (28%), Positives = 112/235 (47%), Gaps = 9/235 (3%) Query: 32 RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMI 91 R WLG KL + L + D E+IL H K Y F +P++G+GL+ SGP R+HRK I Sbjct: 103 RFWLGPKLFIILAEPRDYEVILGCHKASYKDKMYEFIEPFVGKGLVSGSGPVHRAHRKAI 162 Query: 92 APTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRK 150 P + L ++ F+ +S E L+ + G FD+ +M T D++ +T +G+ Sbjct: 163 MPMLNSKALNEYLKHFDTHSRICSELLEEKAGTGVFDIQPFMVHCTFDMIFDTILGMPGS 222 Query: 151 TQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIK 210 +Q E + KM +++H R K W+ ++ +F T K+Q + +IH + Sbjct: 223 SQKEGHKELVYWTEKMYELVHTRMIKVWLHADWIFSWTDLGKKQKEGQHVIHSFIETAVA 282 Query: 211 NKKETYLENKAKGIIPP-----TLEEFTHHSGEILANNAKTLSD---TVFKGYRD 257 KK+ + + I P LE+ H+ + N L D T+F +D Sbjct: 283 RKKKEHYAIERDAIAPDRPRLMLLEQLIDHNAKTNLMNDTELRDETYTIFTAAQD 337 >UniRef50_Q16L55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 463 Score = 155 bits (376), Expect = 3e-36 Identities = 79/185 (42%), Positives = 116/185 (62%), Gaps = 3/185 (1%) Query: 264 ENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323 EN G+K ++ FLD + E + ++S +I E +DTI+F G+DTTA S +L +L + Sbjct: 271 ENTDGKKPQI-FLDKLFELAVENKQQLSKEDIPEHLDTIIFAGNDTTATTMSNLLLMLAM 329 Query: 324 HQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383 H DVQ RVY E+ + D ++P + DT ++ Y E V E++RL+P P+I R D+ Sbjct: 330 HPDVQERVYQEVMEACPDLEQPVSMEDTAKLTYTEMVCKETMRLFPVGPLIGRIAEVDIK 389 Query: 384 ISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442 IS + +VIPAG+ V G +M+HR K + E FNPD+FLPEN H Y+Y+PFS G Sbjct: 390 ISDE-HVIPAGSEVGCGIYMVHRDRKIWGPRAEEFNPDHFLPENISKIHPYAYLPFSGGI 448 Query: 443 RSCVG 447 R+C+G Sbjct: 449 RNCIG 453 Score = 79.4 bits (187), Expect = 2e-13 Identities = 56/227 (24%), Positives = 108/227 (47%), Gaps = 8/227 (3%) Query: 6 HVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY 65 + +E + + V L Y+ G + LG +V + + ++ +L+S I + Y Sbjct: 51 YTSQEKIFETFVELGSTYSSPMG----IELGPITLVVVYQPEHLQAVLSSPHCISRPFWY 106 Query: 66 RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK- 124 FF+ + G+ S WR RK++ +F IL FV IFN+ S + + + S VG+ Sbjct: 107 DFFR--VSRGIFSSPAHIWRGQRKVLNHSFGPGILNCFVSIFNEKSEILTKLMTSHVGRG 164 Query: 125 TFDVHDYMSGTTVDILLETAMGISRKTQD-ESGFDYAMAVMKMCDIIHQRHYKFWMRSEI 183 D ++ +D + TA G++ Q+ G Y A + ++ +R + SE Sbjct: 165 ERDFGHEIARAALDTIYSTAFGLNFGMQEAPEGSKYLEAQEEFIGLVLKRIFSVINYSER 224 Query: 184 VFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLE 230 +++LT +K++ +LL LTN++++ + + + A G+ T E Sbjct: 225 IYRLTKDYKREQELLSYARTLTNRIMQARNAEQILSGAIGLPSVTTE 271 >UniRef50_P13584 Cluster: Cytochrome P450 4B1; n=32; Euteleostomi|Rep: Cytochrome P450 4B1 - Homo sapiens (Human) Length = 511 Score = 155 bits (376), Expect = 3e-36 Identities = 79/231 (34%), Positives = 129/231 (55%), Gaps = 3/231 (1%) Query: 267 VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326 + ++ L FLD+++ + K+SD +++ EVDT MFEGHDTT +G S+ L + ++ + Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336 Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386 Q R +E+ +I GD D + D +M YL I ES RLYPPVP + R+L++ VT Sbjct: 337 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-V 394 Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446 +PAG+ + + + LHR + DPEVF+ F EN RH ++++PFSAGPR+C+ Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454 Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 G+++A F + K+ ++L+ GF + ++P Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMP-QLVLRSKNGFHLHLKP 504 Score = 95.1 bits (226), Expect = 4e-18 Identities = 54/220 (24%), Positives = 103/220 (46%), Gaps = 6/220 (2%) Query: 5 IHVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATE 64 + +QE K+V+ +A F +W G + + D + S Sbjct: 59 LEIQETGSLDKVVS----WAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDV 114 Query: 65 YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEV 122 Y FF W+G GLL+ GPKW HRK++ P FH ++LK +V +F +++ +++K K+ Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174 Query: 123 GKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSE 182 GK+FD+ + ++ L++ G Y +AV + ++ QR F ++ Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHND 234 Query: 183 IVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAK 222 ++ LT ++ + + H T++VI+ +K + K + Sbjct: 235 FIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVR 274 >UniRef50_UPI00015B5196 Cluster: PREDICTED: similar to cytochrome P450 CYP4C39; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4C39 - Nasonia vitripennis Length = 507 Score = 154 bits (373), Expect = 6e-36 Identities = 75/233 (32%), Positives = 132/233 (56%), Gaps = 5/233 (2%) Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328 EK + L ++ + + TN++++ E+++E+ TI DT A SSF + +LGIH DVQ Sbjct: 276 EKSKTCILHRLL-TVNSVTNELTEEELRDEIYTIYIASQDTLAVTSSFAVLMLGIHGDVQ 334 Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 + E+ ++ G D ++KYLE VI E+LRL+P P++ R+LN ++ + N Sbjct: 335 KKARSEVDEVIGVGD--VNIESLSKLKYLEMVIKETLRLFPIAPLMVRQLNGELKLD--N 390 Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 ++P VVI + HR K++++PE F P+ F + T RH Y++IPFS GP C+G+ Sbjct: 391 SILPKDCQVVIAPYATHRSSKFWENPENFLPERFAIKETVKRHPYTFIPFSGGPMGCIGQ 450 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRV 501 KYA + + S++ ++ KL+ DI ++ G+++ ++ R + Sbjct: 451 KYALTALKMILANILQKYVVESDVTLRDIKLKTDISIRSMNGYKISLQARTNI 503 Score = 137 bits (331), Expect = 7e-31 Identities = 75/261 (28%), Positives = 133/261 (50%), Gaps = 6/261 (2%) Query: 3 LNIHVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKA 62 L + + L +++V++ YA +R+W+G L V + + DIE++LNS K Sbjct: 58 LKFACEPDQLLERIVDVIAPYADV--TPMRLWMGPMLYVIITEPRDIEVVLNSQQATSKG 115 Query: 63 TEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV 122 + Y+F P++G GL+ SG W++HRK+I+ + L SF+ F++ S V+KL+ Sbjct: 116 SAYKFLYPFIGNGLISGSGKSWKAHRKIISHILNQRTLDSFIETFDRRSKEFVKKLEPLA 175 Query: 123 -GKTFDVHDYMSGTTVDILLETAMG---ISRKTQDESGFDYAMAVMKMCDIIHQRHYKFW 178 G+ FD+ + G T+D++ ET MG I+ F + A +M IIH R K W Sbjct: 176 NGEVFDIFHSLEGCTIDLVCETVMGYTDINALDNPNKEFVHYTADFRMYKIIHNRMMKIW 235 Query: 179 MRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGE 238 + + +F++TS + Q + +IH T + I+ ++ L+ K+K I L + E Sbjct: 236 LYPDWIFRITSNYSNQKRAQTMIHNFTERCIEAGRQDMLKEKSKTCILHRLLTVNSVTNE 295 Query: 239 ILANNAKTLSDTVFKGYRDDL 259 + + T++ +D L Sbjct: 296 LTEEELRDEIYTIYIASQDTL 316 >UniRef50_Q179B7 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 543 Score = 154 bits (373), Expect = 6e-36 Identities = 111/476 (23%), Positives = 224/476 (47%), Gaps = 23/476 (4%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86 + ++RVW G K+++F D ++ +L S ++K Y F +GL S WRS Sbjct: 65 YDRMVRVWAGPKMLLFTSHPDLVQQLLTSPACLEKPFLYSF--AGFEQGLFTSKYKLWRS 122 Query: 87 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL-KSEVGKTFDVHDYMSGTTVDILLETAM 145 RK + +F++ IL F+ +F Q + +VE L ++ G +H + S T+++ T + Sbjct: 123 MRKRLNSSFNLRILHGFIPVFVQCARKMVEDLNENPDGTVVSMHKFTSVCTLEMACGTTL 182 Query: 146 GISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205 G S T+ E ++ + +R + IV+ LT + ++ + G++ Sbjct: 183 G-SDITRREGKEEFVHGLDIAFGEAARRMVSVHLYPNIVYHLTKYHRELVQARGVVCDFF 241 Query: 206 NKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLS-DTVFKGYRDDLDFNDE 264 ++V L G+I + + +++ T+S + K ++LDF Sbjct: 242 SRV-------SLFPPFFGVIMSHIIDCCMFYFQLVTERRNTMSLNCNKKTNEEELDF--- 291 Query: 265 NDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324 ++K +D ++ +++G SD EI++ + ++ +DT+ + L + Sbjct: 292 ----DRKPKILIDQLLSVNRDG-KSFSDTEIEDNIYAVITGANDTSGLLIAHACLFLCFY 346 Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384 +D++ +++ E+ + + + ++ YLE+ + E LR P P I+R+ ++ I Sbjct: 347 KDIEEKLFTEIMEFMPNEEFEINPESLKQLSYLEKFLKECLRHCPVAPNISRENMSEIEI 406 Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443 +P G ++ + LHR+ + D + F+P+ F E ++NRH ++Y+PFS G R Sbjct: 407 D--GMKVPPGNIFIMNFYALHRRKDIWGPDADKFDPEQFSEERSRNRHPFAYLPFSGGNR 464 Query: 444 SCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 C+G +YA RNF+ +EI ++ + + D+ +K +KV RK Sbjct: 465 ICIGWRYAMFSMKVMLIYLIRNFQFETEIRPEQVRYRHDLTMKLPFEHMIKVTRRK 520 >UniRef50_UPI0000F2BA18 Cluster: PREDICTED: similar to Cytochrome P450 4A2 precursor (CYPIVA2) (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2); n=1; Monodelphis domestica|Rep: PREDICTED: similar to Cytochrome P450 4A2 precursor (CYPIVA2) (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2) - Monodelphis domestica Length = 519 Score = 153 bits (370), Expect = 1e-35 Identities = 74/236 (31%), Positives = 130/236 (55%), Gaps = 3/236 (1%) Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321 ++++ V +KK L FLD++ ++ ++ E++ EV+T F G DT A G S+ L L Sbjct: 285 SEKDKVPKKKYLNFLDILFQAKDEDGGGFTNEELENEVNTFRFAGQDTVAVGFSWTLYCL 344 Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381 ++ + Q + +E+ I D + T+ +M Y I ES R+Y P+P +AR LN+ Sbjct: 345 AMNPEYQKKCREEIQGILKDGES-ITWDHLTQMTYSTMCIKESFRMYSPIPKVARTLNQP 403 Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441 +T +P+ TTV I + LH P +++P+VF+P+ F PENT+ RH Y+++PFSAG Sbjct: 404 ITFPD-GQTLPSDTTVTINIWALHYNPAIWENPKVFDPERFTPENTKKRHPYAFLPFSAG 462 Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 R+C+G+++A F + ++ + + I+L+ GF ++P Sbjct: 463 LRNCIGQQFAMNLIKVSLALTLLRFELLPDLEKPPIPI-SQIVLRSTSGFHFYLKP 517 Score = 80.2 bits (189), Expect = 1e-13 Identities = 44/157 (28%), Positives = 81/157 (51%), Gaps = 4/157 (2%) Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV---EKLKSEVGKTFDVH 129 G+GLL G KW HR+++ P FH NILK ++ I + ++ EKL+++ + DV Sbjct: 136 GKGLLSLEGEKWHYHRRLLTPAFHFNILKDYIYIMRNTVSLMLDKWEKLRTK-DSSIDVF 194 Query: 130 DYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTS 189 D++S ++D L+ G+ ++ES F Y + K+ ++ +R F S+ ++KLTS Sbjct: 195 DFISYMSLDTSLKATFGLQDFNKEESLFSYFQNMNKLLYLVRKRMETFLYYSDFIYKLTS 254 Query: 190 FFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIP 226 + + K+I++++ Y K +P Sbjct: 255 DHYEFQTTCKELKEEPAKIIRHRRALYKNQSEKDKVP 291 >UniRef50_UPI0000D9991B Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily A, polypeptide 11 isoform 1; n=3; Catarrhini|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily A, polypeptide 11 isoform 1 - Macaca mulatta Length = 487 Score = 152 bits (369), Expect = 2e-35 Identities = 80/229 (34%), Positives = 127/229 (55%), Gaps = 5/229 (2%) Query: 267 VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326 V KK L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H Sbjct: 251 VKRKKHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPK 310 Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386 Q R +E++ + GD T+ +M Y I E+LRLYPPVP I+R+L+ VT Sbjct: 311 HQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGISRELSTPVTF-P 368 Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446 +P G TV++ + LH PK + +PEVF+P F P + Q H ++++PFS G R+C+ Sbjct: 369 DGRSLPKGITVMLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQ--HSHAFLPFSGGSRNCI 426 Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKV 495 G+++A F + + P + ++LK G +++ Sbjct: 427 GKQFAMNELKVATALTLLRFELLPD-PTRIPIPMARLVLKSKNGIHLRL 474 Score = 80.6 bits (190), Expect = 9e-14 Identities = 49/170 (28%), Positives = 84/170 (49%), Gaps = 5/170 (2%) Query: 6 HVQEENLTQKLVNLALGYAQTFGNVIRVWL-GSKLIVFLVDADDIEIILNSHVHIDKATE 64 H QE Q+L + + + F + +WL G K V L D D +++IL Sbjct: 62 HKQEFQQDQELQRIRK-WVEMFPSACPLWLWGGKARVQLHDPDYMKVILGRS-DPKSQDP 119 Query: 65 YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK 124 YRF PW+G GLL+ +G W HR+M+ P FH +ILK++V + + +++K + +G+ Sbjct: 120 YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKAYVALMADSVRVMLDKWEKLLGQ 179 Query: 125 --TFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQ 172 +V ++S T+D +++ A Q +S + C + HQ Sbjct: 180 DSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDSLTSTGRWTHRACQLAHQ 229 >UniRef50_UPI0000D56470 Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=5; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 495 Score = 150 bits (364), Expect = 7e-35 Identities = 86/237 (36%), Positives = 136/237 (57%), Gaps = 9/237 (3%) Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321 +DEN +KKR FL+ ++ +S+ +I + I EE+ TI+ G +TTA V +L Sbjct: 262 DDENY--KKKR--FLNHLLTTSETNP-QIDELAILEEIQTILVTGSETTAITIGMVFIIL 316 Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381 GI+ ++Q +V EL I G DR T D ++YLERVI E+LR+ P VP+I R + +D Sbjct: 317 GIYPEIQEKVRSELELILGPDDREITLEDINNLEYLERVIKETLRVLPIVPLITRTVEQD 376 Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441 V + TK IP+G+ V++ + ++ +++ +P+ F+PD FLPEN NR S+IPFS G Sbjct: 377 VKLGTK--TIPSGSFVLVPIASIGKKAEFWAEPKKFDPDRFLPENNANRPRCSFIPFSYG 434 Query: 442 PRSCVGRKYAXXXXXXXXXXXXR--NFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496 PR+C+G KY R F+ ++ +L ++ K GF++K+E Sbjct: 435 PRNCIGFKYGMMSLKVLLATVIRKFTFKPSQYRRIEDVRLIYGMVAKPKHGFKVKIE 491 Score = 94.3 bits (224), Expect = 7e-18 Identities = 56/199 (28%), Positives = 100/199 (50%), Gaps = 8/199 (4%) Query: 25 QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKW 84 +T +V + WLG L+V +D+EI+LN++ K Y F GLLI+ W Sbjct: 71 ETQPSVFKFWLGKDLLVVTSKPEDVEIVLNNNSCFGKPKFYDFAFKLFRNGLLIAPASIW 130 Query: 85 RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETA 144 R R++I PTF+ IL SF+ IF ++ N +V+ L+ ++ D+ + T DI ET Sbjct: 131 RDRRRVINPTFNPKILNSFIEIFGKHGNKLVKVLEESCSES-DIFLKLFRCTFDIACETL 189 Query: 145 MGISR---KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGII 201 + K QD+ Y V++M DI+ R + W+ + ++K + + K+ K + Sbjct: 190 ADVDSELIKGQDK----YLQTVIRMEDILAIRSFSIWLHPDFLWKRSFYGKEMEKASAEV 245 Query: 202 HGLTNKVIKNKKETYLENK 220 +++ KK + +++ Sbjct: 246 FAFVKQILALKKASVTDDE 264 >UniRef50_Q6TGT4 Cluster: Thromboxane A synthase 1; n=6; cellular organisms|Rep: Thromboxane A synthase 1 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 546 Score = 148 bits (359), Expect = 3e-34 Identities = 113/484 (23%), Positives = 216/484 (44%), Gaps = 28/484 (5%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHI--DKATEYRFFKPWLGEGLLISSGPKW 84 +G + ++G + V + D D + ++ + ++ T KP + + L++ G +W Sbjct: 78 YGRICGYYIGRRSTVIIADPDMLRQVMVKEFNKFPNRMTARGITKP-MSDSLIMLKGEQW 136 Query: 85 RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS--EVGKTFDVHDYMSGTTVDILLE 142 + R ++ PTF +K V + N + ++ LKS E +F++H T+D++ Sbjct: 137 KRVRSILTPTFSAAKMKEMVPLINTATETLLRNLKSHAESENSFNIHKCFGCFTMDVIAS 196 Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYK-FWMRSEIVFK-LTSFF--KQQTKLL 198 A G +Q+ + K R F+M + + L K + ++ Sbjct: 197 VAFGTQVDSQNNPDDPFVHQASKFFAFSFFRPIMIFFMAFPFLLRPLAGLLPNKSRDEMN 256 Query: 199 GIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDD 258 K+IK + + E + K + L+ T++ + + ++D + Y Sbjct: 257 SFFTQCIQKMIKQRDDLSPEQRRKDFLQLMLDVRTNNKF-LSVEHFDVVNDADEEAY--- 312 Query: 259 LDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318 D ++ + E + S Q +++ EI + + G++T++ +F Sbjct: 313 -DGHENSPANESTK--------RSQQK--RMMTEDEIVGQSFIFLVAGYETSSNTLAFTC 361 Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKL 378 LL +H + Q ++ +E+ + F + +A+ E+KYL+ VI ESLRLYPP +AR + Sbjct: 362 YLLAVHPECQKKLQEEVDEFFSRHEM-VDYANVQELKYLDMVICESLRLYPPAFRVARDV 420 Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPF 438 D ++ + +P G ++ I T LH P+++ +P F P+ F PE RH + Y+PF Sbjct: 421 EEDTVLNGQ--FLPKGASLEIPTGFLHYDPEHWTEPTKFIPERFTPEAKARRHPFVYLPF 478 Query: 439 SAGPRSCVGRKYAXXXXXXXXXXXXRNFRTIS-EIPEKEFKLQGDIILKRAEGFQMKVEP 497 AGPRSCVG + A R F ++ E E +L+ L G +K+ Sbjct: 479 GAGPRSCVGMRLAQLEIKVALVHIFRRFNVLACEDTEIPLELKSHTTLGPKNGVMVKITE 538 Query: 498 RKRV 501 R+ + Sbjct: 539 RENL 542 >UniRef50_Q6PW73 Cluster: Cytochrome P450 CYP4AT1; n=1; Capitella capitata|Rep: Cytochrome P450 CYP4AT1 - Capitella capitata Length = 490 Score = 147 bits (357), Expect = 5e-34 Identities = 84/250 (33%), Positives = 138/250 (55%), Gaps = 5/250 (2%) Query: 248 SDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGH 307 SD+ +G R++ + N V + + L FLD+++++ + ++D EI+ EVDT MFEGH Sbjct: 244 SDSRQEG-REEKKRSRRNQV-DSQNLDFLDILLDAKDSDGRGLTDEEIQHEVDTFMFEGH 301 Query: 308 DTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRL 367 DTTA+G S+ L L H + Q R E+ + GD + D ++ +L I ESLRL Sbjct: 302 DTTASGLSWCLYNLARHPEYQDRCRKEVMDVMGDRS-DVEWDDMSKLTFLTMCIKESLRL 360 Query: 368 YPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENT 427 +P VP I R L + +T +PA T + I + H +++PE ++P+ F EN+ Sbjct: 361 HPAVPNIGRSLTKPMTF-PDGRTVPAETDLGIAIYGCHHNSALWENPEQYDPERFNAENS 419 Query: 428 QNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKR 487 ++R +S+IPFSAGPR+C+G+ +A +NF+ + + +L ++LK Sbjct: 420 KDRPPHSFIPFSAGPRNCIGQHFAMHEMRSVLAVCLKNFQLRID-DTRILELLPQLVLKA 478 Query: 488 AEGFQMKVEP 497 G +KV P Sbjct: 479 KGGLWLKVTP 488 Score = 85.0 bits (201), Expect = 4e-15 Identities = 47/180 (26%), Positives = 96/180 (53%), Gaps = 5/180 (2%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82 +++ F + +G + + L + +L++ D+ + YR KPW+G+GLL+SSG Sbjct: 56 WSELFDGLFSYCIGLYVCMELSHPSPLSKLLSTAEPKDRIS-YRTIKPWIGDGLLVSSGE 114 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT---FDVHDYMSGTTVDI 139 KW +R+++ P FH ++LK +VGIF+ +N + +K + + K ++ ++S T+D Sbjct: 115 KWARNRRLLTPAFHFDVLKPYVGIFSSTANIMADKWRKILSKNDEPLEMFQHVSLMTLDS 174 Query: 140 LLETAMGISRKTQDES-GFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLL 198 LL+ G + Q+E Y +V ++ +++ +R F + ++ T Q + +L Sbjct: 175 LLKCIFGQTGSVQNEGRDGSYIRSVYQLTELVMKRFQFFPYLIDWIYYFTPSALQVSPML 234 >UniRef50_Q02928 Cluster: Cytochrome P450 4A11 precursor; n=114; Tetrapoda|Rep: Cytochrome P450 4A11 precursor - Homo sapiens (Human) Length = 519 Score = 147 bits (355), Expect = 9e-34 Identities = 76/229 (33%), Positives = 124/229 (54%), Gaps = 5/229 (2%) Query: 267 VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326 + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H Sbjct: 283 IKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPK 342 Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386 Q R +E++ + GD T+ +M Y I E+LRLYPPVP I R+L+ VT Sbjct: 343 HQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF-P 400 Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446 +P G V++ + LH PK + +PEVF+P F P + Q H ++++PFS G R+C+ Sbjct: 401 DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRNCI 458 Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKV 495 G+++A F + + + ++LK G +++ Sbjct: 459 GKQFAMNELKVATALTLLRFELLPDPTRIPIPI-ARLVLKSKNGIHLRL 506 Score = 97.9 bits (233), Expect = 6e-19 Identities = 59/212 (27%), Positives = 111/212 (52%), Gaps = 6/212 (2%) Query: 6 HVQEENLTQKLVNLALGYAQTFGNVIRVWL-GSKLIVFLVDADDIEIILNSHVHIDKATE 64 H+QE Q+L + + +TF + WL G K+ V L D D +++IL + Sbjct: 62 HIQELQQDQELQRIQK-WVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS- 119 Query: 65 YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK 124 YRF PW+G GLL+ +G W HR+M+ P FH +ILK +VG+ + +++K + +G+ Sbjct: 120 YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQ 179 Query: 125 --TFDVHDYMSGTTVDILLETAMGISRKTQ-DESGFDYAMAVMKMCDIIHQRHYKFWMRS 181 +V ++S T+D +++ A Q D + Y A+ + +++ R + ++ Sbjct: 180 DSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQN 239 Query: 182 EIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213 + ++ LTS + + + H T++VI+ +K Sbjct: 240 DTIYSLTSAGRWTHRACQLAHQHTDQVIQLRK 271 >UniRef50_Q9VG40 Cluster: Probable cytochrome P450 313a4; n=3; Sophophora|Rep: Probable cytochrome P450 313a4 - Drosophila melanogaster (Fruit fly) Length = 478 Score = 145 bits (352), Expect = 2e-33 Identities = 73/214 (34%), Positives = 125/214 (58%), Gaps = 5/214 (2%) Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 FL+L+ + + G + + +++E + I+F +TTA + L LL + + Q R ++E Sbjct: 255 FLNLVTDLMRRGVFTLKN--VEDESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEE 312 Query: 335 LYQIFGDS-DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPA 393 + IF ++ D ++ADT +M YL+ ++ ES+R+ PPVPV++R+ ++D+ +S V+P Sbjct: 313 IKTIFPNTGDFDVSYADTQQMVYLDLILNESMRVIPPVPVVSRQTSQDLKLSN-GIVVPK 371 Query: 394 GTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 452 G + I + +HR K + D E FNPD+FLP N Q++H Y+YIPF+ G R+C+G +YA Sbjct: 372 GVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQDKHPYAYIPFTKGIRNCIGWRYAL 431 Query: 453 XXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486 RN+R + P + DI +K Sbjct: 432 ISAKVTLAKLLRNYRFKTSFPFENLYFVEDITMK 465 Score = 56.4 bits (130), Expect = 2e-06 Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Query: 28 GNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSH 87 G I WLG + + D ++ I S ++K Y+ G GL P+W H Sbjct: 65 GPTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAGVGLFSLKDPRWSIH 124 Query: 88 RKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAM 145 RK++ P F +L SF+ IFN+ + ++++L+ + G+ D+ + T+ I +T M Sbjct: 125 RKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEK-DLIPLLQSFTLGIATQTTM 183 Query: 146 GISRKTQDESGF 157 G K DE F Sbjct: 184 GSDVK--DEESF 193 >UniRef50_Q4U3Y4 Cluster: CYP325C2; n=4; Anopheles gambiae|Rep: CYP325C2 - Anopheles gambiae (African malaria mosquito) Length = 264 Score = 144 bits (350), Expect = 4e-33 Identities = 78/230 (33%), Positives = 126/230 (54%), Gaps = 4/230 (1%) Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329 KK L F D ++ + NG N +D E+ + +++ G+DTTA + L +H +Q Sbjct: 37 KKPLIFADQLLAAQHNG-NPFTDIEVTHNIYSMIAAGNDTTALQVTHTCLFLAMHPAIQE 95 Query: 330 RVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389 RVY E+ +F D D+ D ++ Y+ERVI ESLRL P P IAR+ +D+ I+ + Sbjct: 96 RVYREVMDVFPDPDQDIEVEDLKKLTYMERVIKESLRLAPSGPNIARQTMKDIEIAGVH- 154 Query: 390 VIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 IP + +V+ F +HR+ + D ++F+PD FLPE ++ R +IPFSAG R+C+G Sbjct: 155 -IPRDSLIVMSIFSMHRRKDIWGPDADLFDPDRFLPERSEGRSTNVFIPFSAGSRNCIGG 213 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 +YA R R S++ + + + D+ LK + ++VE R Sbjct: 214 RYAMLSMKVMLSSILRRLRLRSDLQMNDLQFRFDLTLKLESEYFVQVEKR 263 >UniRef50_Q16L50 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 428 Score = 144 bits (350), Expect = 4e-33 Identities = 79/240 (32%), Positives = 130/240 (54%), Gaps = 4/240 (1%) Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319 D+ D+ DVG KK F++ +++ Q + I +I + + T+ F G+DTTA S +L Sbjct: 192 DYQDK-DVGAKKIPIFVEKLLDEIQK-SGHIKREDIDDHIVTMCFAGNDTTATTMSNILL 249 Query: 320 LLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLN 379 +L +H D+Q RVY E+ D ++ + D ++ Y E V E++R + PVI R Sbjct: 250 MLAMHPDIQERVYQEIIAACPDRNQQVSIEDAGKLTYTEMVCKETMRHFSIAPVIGRTAT 309 Query: 380 RDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPF 438 +DV ++ + IPA +T++ + LH PK + D + FNPDNFLP+ RH YS++PF Sbjct: 310 QDVKLN-DDITIPANSTLICCFYKLHMDPKNWGPDVKNFNPDNFLPDLVAKRHPYSFLPF 368 Query: 439 SAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 S GPR+C+G +YA R +R + + ++ + +K +G + VE R Sbjct: 369 SGGPRNCLGVRYAWLSMKIMLVHILRRYRLRTTLTMDTITVKFNSFMKIEDGCPITVEER 428 Score = 82.6 bits (195), Expect = 2e-14 Identities = 48/173 (27%), Positives = 90/173 (52%), Gaps = 8/173 (4%) Query: 35 LGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPT 94 +G + +F+ + ++++LNS ++K +Y FF+ + G+ + W+ RK+I P+ Sbjct: 1 MGPMVYIFVYTPEQLQVVLNSPHCLEKPLQYSFFQ--VSRGIFSAPVDLWKILRKLITPS 58 Query: 95 FHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRKTQ- 152 F +L SFV IFN+ S+ +VE++ VGK D + + +D + TA G+ Q Sbjct: 59 FGPGLLSSFVPIFNEKSSVMVEQMAKNVGKPQRDYYSEIVLCFMDTICNTAFGVDCDLQR 118 Query: 153 DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTS----FFKQQTKLLGII 201 +G +Y K DI+ +R+ K W +++ T+ F K+ K L ++ Sbjct: 119 SPAGAEYVETQEKYIDIVTERYLKPWQYLNFIYRFTNAYQIFKKRHGKFLALL 171 >UniRef50_Q8N118 Cluster: Cytochrome P450 4X1; n=12; Mammalia|Rep: Cytochrome P450 4X1 - Homo sapiens (Human) Length = 509 Score = 144 bits (350), Expect = 4e-33 Identities = 80/250 (32%), Positives = 130/250 (52%), Gaps = 4/250 (1%) Query: 248 SDTVFKGYRDDLDFNDENDVGEKKRLA-FLDLMIESSQNGTNKISDHEIKEEVDTIMFEG 306 +DT+ + + L + D K++ FLD+++ + + SD ++ EV T + G Sbjct: 258 TDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAG 317 Query: 307 HDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLR 366 HDT AA S++L L ++ + Q R +E+ I GD T+ EM Y I E+ R Sbjct: 318 HDTLAASISWILYCLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCR 376 Query: 367 LYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPEN 426 L P VP I+R L++ +T +PAG TVV+ + LH P +K+P+VF+P F EN Sbjct: 377 LIPAVPSISRDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQEN 435 Query: 427 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486 + RH Y+Y+PFSAG R+C+G+++A +FR ++ P + ILK Sbjct: 436 SDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFR-VTPDPTRPLTFPNHFILK 494 Query: 487 RAEGFQMKVE 496 G + ++ Sbjct: 495 PKNGMYLHLK 504 Score = 95.9 bits (228), Expect = 2e-18 Identities = 60/216 (27%), Positives = 115/216 (53%), Gaps = 15/216 (6%) Query: 7 VQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLV-DADDIEIILNSHVHIDKATEY 65 +Q++N+ +KL + Y + F W+G F + D D + +L+ D ++Y Sbjct: 61 IQDDNM-EKLEEIIEKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQY 112 Query: 66 --RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV---EKLKS 120 +F P LG+GL GPKW HR+++ P FH NILK+++ + + ++ EK+ S Sbjct: 113 LQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICS 172 Query: 121 EVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFD-YAMAVMKMCDIIHQRHYKFWM 179 + +V+++++ ++DI+++ A Q S D YA A+ ++ II R Y Sbjct: 173 TQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLY 232 Query: 180 RSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKET 215 S+I+FKL+ + KL +++ T+ +I+ +K++ Sbjct: 233 HSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKS 268 >UniRef50_Q6NT55 Cluster: Cytochrome P450 4F22; n=127; Deuterostomia|Rep: Cytochrome P450 4F22 - Homo sapiens (Human) Length = 531 Score = 144 bits (349), Expect = 5e-33 Identities = 72/228 (31%), Positives = 125/228 (54%), Gaps = 3/228 (1%) Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330 K L F+D+++ + ++SD +I+ E DT MFEGHDTT++G S++L L + + Q + Sbjct: 301 KTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEK 360 Query: 331 VYDELYQIF-GDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389 +E+ ++ G + D ++ + I ESLR YPPV +++R+ D+ + Sbjct: 361 CREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGR- 419 Query: 390 VIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449 +IP G ++ + H P + D +V+NP F P+N Q R +Y+PFSAGPR+C+G+ Sbjct: 420 IIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQS 479 Query: 450 YAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 +A FR +S ++ + + ++IL+ G +KVEP Sbjct: 480 FAMAELRVVVALTLLRFR-LSVDRTRKVRRKPELILRTENGLWLKVEP 526 Score = 99.1 bits (236), Expect = 2e-19 Identities = 55/200 (27%), Positives = 109/200 (54%), Gaps = 7/200 (3%) Query: 29 NVIRVWLGSKL-IVFLVDADDIEIILNSHVHIDKATE--YRFFKPWLGEGLLISSGPKWR 85 +V+ VW+G L ++ LV D I+ +L + I + Y F KPWLG+GLL+S G KW Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153 Query: 86 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTTVDILLE 142 HR+++ P FH +ILK ++ IFNQ+++ + K L + D+ +++S T+D L + Sbjct: 154 RHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQK 213 Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202 + Q++ DY A++++ + +R Y+ + ++ ++ ++ + ++H Sbjct: 214 CVFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVH 272 Query: 203 GLTNKVIKNKKETYLENKAK 222 T +VI+ ++ + A+ Sbjct: 273 HFTTEVIQERRRALRQQGAE 292 >UniRef50_Q6SPQ6 Cluster: CYP4BB1; n=2; Protostomia|Rep: CYP4BB1 - Nereis virens (Sandworm) Length = 508 Score = 144 bits (348), Expect = 6e-33 Identities = 80/254 (31%), Positives = 134/254 (52%), Gaps = 6/254 (2%) Query: 247 LSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEG 306 +++TV R+ L N + + ++K L FLD+++++ +SD EI+ EVDT MFEG Sbjct: 259 VAETVISQRRETLQENPDA-LEDRKYLDFLDILLQARDEDGTGLSDLEIRNEVDTFMFEG 317 Query: 307 HDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTL-EMKYLERVILESL 365 HDTTA+G S+ L L H + Q + E+ ++ D D L ++ YL + ES+ Sbjct: 318 HDTTASGISWALYSLAKHPEFQKKAQQEIDELLADRKNKWIMWDDLNQLPYLTMCLKESM 377 Query: 366 RLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLP 424 RL+ PVPVI+R+L +TI +P T I LH P + +D + + P+ FLP Sbjct: 378 RLWCPVPVISRQLLNPITID--GVTLPPHTLFDINIIALHHNPTVWGEDHDEYKPERFLP 435 Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDII 484 EN ++++PFSAGPR+C+G+ +A + F +S + +++ Sbjct: 436 ENINKMDNFAFLPFSAGPRNCIGQNFAFNEMKTTIARIIQRF-DLSVDESHPVYPRPEVV 494 Query: 485 LKRAEGFQMKVEPR 498 + G ++ + PR Sbjct: 495 TRAIHGIKLFMNPR 508 >UniRef50_Q8K4D6 Cluster: Cytochrome P450 4X1; n=15; Eutheria|Rep: Cytochrome P450 4X1 - Rattus norvegicus (Rat) Length = 507 Score = 143 bits (347), Expect = 8e-33 Identities = 69/198 (34%), Positives = 116/198 (58%), Gaps = 2/198 (1%) Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 FLD+++ + SD +++ EV+T M+ GHD +AA S++L L ++ + Q R E Sbjct: 284 FLDIVLSAQAGDEKAFSDADLRSEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTE 343 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + I GD T+ E+ Y I E+LRL PP+P I+R+L++ +T+ + +PAG Sbjct: 344 IRSILGDGSS-ITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSKPLTLPD-GHSLPAG 401 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454 TVV+ + LH P +KDP+VF+P F EN++ RH +++PFS+GPR+C+G+++A Sbjct: 402 MTVVLSIWGLHHNPAVWKDPKVFDPLRFTKENSEQRHPCAFLPFSSGPRNCIGQQFAMLE 461 Query: 455 XXXXXXXXXRNFRTISEI 472 FR +++ Sbjct: 462 LKVAIALTLLRFRVAADL 479 Score = 97.9 bits (233), Expect = 6e-19 Identities = 72/250 (28%), Positives = 124/250 (49%), Gaps = 16/250 (6%) Query: 7 VQEENLTQKLVNLALGYAQTFGNVIRVWLGS-KLIVFLVDADDIEIILNSHVHIDKATEY 65 +QE+N+ +KL + Y F W+G + ++ D D +I L+ D T+Y Sbjct: 61 LQEDNM-EKLDEIVKEYPCAFP----CWVGPFQAFFYIYDPDYAKIFLS---RTDPKTQY 112 Query: 66 --RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV---EKLKS 120 + P+LG GLL GP+W HR ++ P FH +ILK V + + N ++ EK + Sbjct: 113 LHQLMTPFLGRGLLNLDGPRWFQHRCLLTPAFHQDILKPCVDMMAHSVNMMLDKWEKTWT 172 Query: 121 EVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFD-YAMAVMKMCDIIHQRHYKFWM 179 T +V ++++ T+DI+++ A G Q ++ Y A ++ +II R Y FW Sbjct: 173 TQETTIEVFEHINLMTLDIIMKCAFGQETNCQINGTYESYVKATFELGEIISSRLYNFWH 232 Query: 180 RSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEI 239 +I+FKL+ +L +IH T K+I+++K+T L+++ T + F Sbjct: 233 HHDIIFKLSPKGHCFQELGKVIHQCTEKIIQDRKKT-LKDQVNQDDTQTSQNFLDIVLSA 291 Query: 240 LANNAKTLSD 249 A + K SD Sbjct: 292 QAGDEKAFSD 301 >UniRef50_Q5XM61 Cluster: Cytochrome P450; n=9; Pancrustacea|Rep: Cytochrome P450 - Anopheles gambiae (African malaria mosquito) Length = 147 Score = 142 bits (345), Expect = 1e-32 Identities = 70/138 (50%), Positives = 94/138 (68%), Gaps = 4/138 (2%) Query: 267 VGEKKRLAFLDLMIESSQNGTNK--ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324 +G +KRLAFLDL+++S+ GT ++D +++EEVDT MFEGHDTT AG S+ L LL +H Sbjct: 10 LGRRKRLAFLDLLLQSATTGTGSPLLTDEDVREEVDTFMFEGHDTTTAGMSWALFLLALH 69 Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384 +VQ RV+ E+ IFG SDRPAT D M+ LER + E+LRLYP V R ++DVT+ Sbjct: 70 PEVQERVHQEIDSIFGGSDRPATMQDLTAMRLLERCLKETLRLYPSVAFFGRTTSKDVTL 129 Query: 385 STKNYVIPAGTTVVIGTF 402 Y +PAGT V I + Sbjct: 130 G--GYHVPAGTIVGIHAY 145 >UniRef50_Q5V5P9 Cluster: Cytochrome P450; n=3; Halobacteriaceae|Rep: Cytochrome P450 - Haloarcula marismortui (Halobacterium marismortui) Length = 445 Score = 142 bits (345), Expect = 1e-32 Identities = 75/213 (35%), Positives = 119/213 (55%), Gaps = 8/213 (3%) Query: 257 DDLDFNDENDVG--EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGS 314 DD+ E+ +G E + FL +++ + +G S ++++E+ T++ GHDTTA Sbjct: 209 DDIIEVREDSLGTDEDGPMDFLSVLLRARDDGNQ--SPEQLRDEMMTMLLAGHDTTALTL 266 Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374 ++ LL H +V+ RV++EL + GD DRP E+ YLE VI E++RLYPPV I Sbjct: 267 TYTWFLLSEHPEVEQRVHEELDDVIGD-DRPG-MEHVRELDYLEWVIQEAMRLYPPVYTI 324 Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434 R+ DVT+S Y + AGTT+++ + +HR ++Y DPE F+P+ + PE R ++ Sbjct: 325 FREPTEDVTLS--GYEVEAGTTLMVPQWGVHRSERFYDDPETFDPERWKPERASERPRFA 382 Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467 Y PF GPR C+G+ A +R Sbjct: 383 YFPFGGGPRHCIGKHLAMLEAQLITATTASQYR 415 Score = 50.4 bits (115), Expect = 1e-04 Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 6/131 (4%) Query: 25 QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYR--FFKPWLGEGLLISSGP 82 + +G+V R +G V L D IE +L S + +++ LG+GLL+S G Sbjct: 33 RAYGDVARFDMGPMDTVMLCDPTAIERVLVSEADRFRKPDFQGDALGDLLGDGLLLSEGE 92 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTVDILL 141 W RK+ P F + L G+ ++ + + +++ G D M+ T+D++L Sbjct: 93 TWEQQRKLANPAFSMARLS---GMADRITGHAEDRIADWSHGDVIDAEQSMTRVTLDVIL 149 Query: 142 ETAMGISRKTQ 152 + MG+ Q Sbjct: 150 DLMMGVELSEQ 160 >UniRef50_Q8WQN5 Cluster: Cytochrome P450 CYP4H14; n=22; Endopterygota|Rep: Cytochrome P450 CYP4H14 - Anopheles gambiae (African malaria mosquito) Length = 151 Score = 142 bits (343), Expect = 3e-32 Identities = 66/153 (43%), Positives = 96/153 (62%), Gaps = 4/153 (2%) Query: 298 EVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPA--TFADTLEMK 355 EVDT MFEGHDTT +G SF + L + DVQ RVY+E+ I G + A T+ + E K Sbjct: 1 EVDTFMFEGHDTTTSGISFTIYELARNPDVQERVYEEIVSILGKDHKTAELTYQNLQEFK 60 Query: 356 YLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPE 415 YL+ V+ E LR+YPPV +I R L D+ ++ +PAG V++ +++HR P+ Y +P Sbjct: 61 YLDLVVKEGLRMYPPVGIIGRALVEDLELN--GTTVPAGQNVLVPIYVIHRNPEIYPNPN 118 Query: 416 VFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 F+P F + R + Y+PFSAGPR+C+G+ Sbjct: 119 QFDPSRFAEDAESKRGPFDYLPFSAGPRNCIGQ 151 >UniRef50_Q176V3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 498 Score = 141 bits (341), Expect = 5e-32 Identities = 118/459 (25%), Positives = 210/459 (45%), Gaps = 48/459 (10%) Query: 32 RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLIS-SGPKWRSHRKM 90 ++ LG K ++ + D ++ +L + DK Y F + LG GL+ SG +W RK+ Sbjct: 70 KLMLGPKPLITISHPDLMQQVLTRNDLYDKPFLYEFLR--LGNGLITERSGERWLQTRKL 127 Query: 91 IAPTFHINILKSFVGIFNQNSNNVVEKLKS--EVGKTFDVHDYMSGTTVDILLETAMGIS 148 + PTF+ ++L SF+ + + +V KL+S + D++ ++ T LE A+ + Sbjct: 128 LGPTFNTSMLTSFLSTMDARTMKMVSKLQSLADGHSEIDIYPFLLTCT----LEIAISTT 183 Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKV 208 D+ ++ Q+ Y + L F K + L ++ + Sbjct: 184 MGRMDD-------------EMPGQQDY--------IRNLEIFLKAVGERLVNVYYFIEPI 222 Query: 209 IKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVG 268 K K + ++A+ I EFTH + +S F+ DF +++ Sbjct: 223 YKLSKAYKIHDEARRIC----NEFTH----------RIVSKRRFEIQSLGEDFQQKDEY- 267 Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328 K+ L LD +I + SD E+ E + T++ G DT+A ++ L ++ +VQ Sbjct: 268 IKQHLNALDQIITMKRPDGTGFSDLEVNEHLYTLIGAGTDTSALNVAYTCLYLAMYPEVQ 327 Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 +V E+ Q+F + + +++Y E VI E LRL+P VP+ AR+ I Sbjct: 328 EKVLTEINQVFYSPEVEVNIENLKQLEYTEMVIKEILRLFPAVPLGARQTMS--AIELDG 385 Query: 389 YVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447 IP ++ F LHR+ + DPE F+P+ F PE + RH ++Y+PFS G R+C+G Sbjct: 386 IRIPKDQIIIFSMFTLHRRKDIWGPDPEQFDPERFRPEAIEARHPFAYLPFSGGLRNCIG 445 Query: 448 RKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486 +YA + F + + + KL+ ++ LK Sbjct: 446 HRYAMNVMRIILLRIMQKFEIQTNMKPTDLKLKFEVTLK 484 >UniRef50_UPI0000D56469 Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily v, polypeptide 2; n=1; Tribolium castaneum|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily v, polypeptide 2 - Tribolium castaneum Length = 392 Score = 140 bits (340), Expect = 6e-32 Identities = 68/158 (43%), Positives = 103/158 (65%), Gaps = 3/158 (1%) Query: 295 IKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEM 354 I+EE+ TI+ ++TA +L +LGI+ ++Q +V EL IFG DR T D +M Sbjct: 187 IEEELQTILITSSESTALTVGMILTVLGIYPEIQKKVSKELDSIFGHDDRETTLEDVQKM 246 Query: 355 KYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDP 414 KYLE VI E+ R+ P VP++AR ++D+ + NY IPAG+ +VI + + + ++K+P Sbjct: 247 KYLECVIKETSRVLPAVPLLARLADKDIKLD--NYTIPAGSIIVIPIWQIGKNADFWKNP 304 Query: 415 EVFNPDNFLPENTQ-NRHYYSYIPFSAGPRSCVGRKYA 451 + F+PD FLPEN NR S+IPFS GPR+C+G +Y+ Sbjct: 305 KKFDPDRFLPENCDPNRPRSSFIPFSYGPRNCIGFQYS 342 Score = 59.7 bits (138), Expect = 2e-07 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 + + WLG L+V D+EIILN+ +K Y F G GLL + W+ RK Sbjct: 77 IFKFWLGQDLVVATSRLKDVEIILNNC--FEKPKFYNFMCEVTGNGLLTARENIWKERRK 134 Query: 90 MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK 124 MI F + +L S+V IF++ + ++ + + GK Sbjct: 135 MINQAFSLKVLHSYVDIFSKRAKCLISWFEEDFGK 169 >UniRef50_A6GGL1 Cluster: Cytochrome P450 family protein; n=1; Plesiocystis pacifica SIR-1|Rep: Cytochrome P450 family protein - Plesiocystis pacifica SIR-1 Length = 454 Score = 140 bits (339), Expect = 8e-32 Identities = 77/249 (30%), Positives = 134/249 (53%), Gaps = 11/249 (4%) Query: 256 RDDLDFNDENDVGEKKRLA-----FLDLMIESSQNGTNKISD-HEIKEEVDTIMFEGHDT 309 RD LD + + E++R LD+++ + T + D ++++E+ T++ GH+T Sbjct: 199 RDTLDAVIQGIIDERRRAGSGPGDLLDMLMAARDEDTGEGMDARQLRDELMTLVVAGHET 258 Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYP 369 T+ S+ LL H + R+ E+ ++ GD R T D ++++ ERV+ ES+R+YP Sbjct: 259 TSNALSWTWYLLSQHPEHVQRLRAEVDEVLGD--RLPTPEDLAKLEHTERVLKESMRVYP 316 Query: 370 PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQN 429 PV + R+ + V + Y +P GT + I ++LHR P+++ DPE F+PD F PE + Sbjct: 317 PVWAVEREPSEAVEVG--GYRLPKGTMIGISPYVLHRDPQHWPDPERFDPDRFTPERSAG 374 Query: 430 RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAE 489 R Y+Y+PF AGPR C+G +A R F + +P + ++ I L+ Sbjct: 375 RPRYAYLPFGAGPRVCIGAGFALTEAKAILAMLVRRF-DLERVPGQAVHMEPGITLRPKH 433 Query: 490 GFQMKVEPR 498 G +M++ R Sbjct: 434 GLRMRLRVR 442 Score = 51.2 bits (117), Expect = 6e-05 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 2/115 (1%) Query: 28 GNVIRVWLGSKLIVFLVDADDI-EIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86 G+ +R G V L D +D+ ++++ K+ Y K LGEGL+ S G W+ Sbjct: 32 GDHVRFRFGPFSYVSLRDLEDVRKVLVTDAQRYTKSKVYTALKLLLGEGLVTSEGAMWQR 91 Query: 87 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTVDIL 140 RK+ +P F + SF + ++ E+ + G DVHD M T+ I+ Sbjct: 92 QRKLSSPAFRPRAVASFTEAMGACTRDLGERWRGLGDGAELDVHDEMMRLTLRIV 146 >UniRef50_Q17DZ0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 504 Score = 140 bits (338), Expect = 1e-31 Identities = 76/229 (33%), Positives = 122/229 (53%), Gaps = 4/229 (1%) Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330 K AFL+ ++ G + +D EI T++ G++TTA + V +L +H D+Q R Sbjct: 266 KSKAFLERLLTIQHKGRS-FTDDEIINHAYTMLVAGYETTALQLTNVCMMLAMHPDIQER 324 Query: 331 VYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYV 390 V E+ IF D ++ YL+ I E++RLYP VP+IAR+ N + + N Sbjct: 325 VASEIKTIFPSLDMEILPEALKDLPYLDMTINETMRLYPVVPLIARQSNSSLELDKVN-- 382 Query: 391 IPAGTTVVIGTFMLHRQPKYYKDPEV-FNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449 IP GT ++ LHR+ + + + FNPDNFLPE + RH Y++IP SAGPR C+G + Sbjct: 383 IPTGTNFIVHIGALHRRKDVWGEEVLDFNPDNFLPEKVERRHPYAFIPLSAGPRVCIGNR 442 Query: 450 YAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 YA + +R +++ K+ K + + LK + +++E R Sbjct: 443 YAMLSLKVFLIRLLQRYRLSTKLTRKDLKFKFQVTLKLKIPYTVQMERR 491 Score = 64.1 bits (149), Expect = 8e-09 Identities = 46/192 (23%), Positives = 96/192 (50%), Gaps = 7/192 (3%) Query: 32 RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISS-GPKWRSHRKM 90 ++WLG ++ + + ++ +LN IDK Y F + LG+GL+ G +WR HRK Sbjct: 67 KIWLGPVPLINVQHPELVQKVLNEC--IDKPFAYDFME--LGQGLVSERYGQRWREHRKT 122 Query: 91 IAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILLETAMGISR 149 ++P F+ IL SF+ IF + +++V+++L+ G+ FD+ +Y S + ++ T M + Sbjct: 123 LSPLFNTKILHSFIPIFERATSDVMKRLEVVCDGRDFDLLEYTSSCSAKMVHGT-MVDTL 181 Query: 150 KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVI 209 +E + + D + +R + ++K++S ++ + + I + N I Sbjct: 182 SVSEEIIHSLITNLDIILDAVGKRILNGVYALKTLYKMSSVYRDEWRSRKICYETVNDGI 241 Query: 210 KNKKETYLENKA 221 + L ++ Sbjct: 242 MKMRMNILNEQS 253 >UniRef50_A1BPR7 Cluster: CYP4AY1; n=2; Ips paraconfusus|Rep: CYP4AY1 - Ips paraconfusus Length = 491 Score = 139 bits (337), Expect = 1e-31 Identities = 78/229 (34%), Positives = 123/229 (53%), Gaps = 6/229 (2%) Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327 G KK++AFLD +++ +SD I+ EVDT+MF GHDTTA +F L LL H +V Sbjct: 261 GGKKKMAFLDHLLQYRDEQGKPLSDAFIRHEVDTVMFAGHDTTAVALAFALYLLAKHPEV 320 Query: 328 QARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387 QA+ E +I ++ T D + YL+ V+ E+LRLYP VP +R L D+ + + Sbjct: 321 QAKARAEAREIVEGREK-LTIKDIQNLNYLDLVVKETLRLYPSVPFYSRALKEDM-VYQE 378 Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447 ++P G V+I + ++R P Y++P+ F P FL + +S + FSAGPR+C+G Sbjct: 379 GKILPKGLVVLIVAYTVNRNPAVYQNPDQFIPTRFLDKEPVP---FSLLSFSAGPRNCIG 435 Query: 448 RKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQGDIILKRAEGFQMKV 495 +K+A F I + E ++ +LK G ++K+ Sbjct: 436 QKFALLELKVALSKLLLRFEFVIPDSDASEPVVEAVTVLKPKNGIRIKL 484 Score = 108 bits (260), Expect = 3e-22 Identities = 53/178 (29%), Positives = 99/178 (55%), Gaps = 2/178 (1%) Query: 45 DADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFV 104 D ++ L S++ I K Y K WLG GLLIS G +WR+ RK++ P FH IL+ F+ Sbjct: 78 DLSFLKWFLTSNIPIHKGDIYAVLKNWLGGGLLISGGEEWRNSRKILTPAFHFTILEQFI 137 Query: 105 GIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMA 162 +F + + + L +EV D++ Y++ T+D++ +T+MG+ Q +S DY A Sbjct: 138 EVFEDATQVLGDVLSAEVTSKGVVDIYPYLTRYTLDVICQTSMGVKLNIQQQSHSDYINA 197 Query: 163 VMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENK 220 V +M II +R + + + TS + ++ + + ++H ++N +I+ +++ + K Sbjct: 198 VAEMGKIIVERAFNPLKVYDFTYIFTSDYWKEKQYVKLLHQVSNSIIEQRRQALEDQK 255 >UniRef50_Q9KFA6 Cluster: Cytochrome P450 hydroxylase; n=1; Bacillus halodurans|Rep: Cytochrome P450 hydroxylase - Bacillus halodurans Length = 453 Score = 139 bits (336), Expect = 2e-31 Identities = 74/225 (32%), Positives = 126/225 (56%), Gaps = 9/225 (4%) Query: 276 LDLMIES-SQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 L ++I + ++ + ++D ++++E+ T+ GH+TTA S+ LL H V+ ++Y E Sbjct: 236 LSMLISTYDEDDGSYMTDRQLRDEIITLFLAGHETTANTLSWAFYLLSQHPHVEEKLYQE 295 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + Q+ G +RPAT D ++ Y E VI E+LR+ P V +I+R+ +DVT+ +Y I AG Sbjct: 296 VSQVLG--NRPATLEDMPKLSYAEHVIKETLRVQPTVWLISRRAEKDVTLG--DYHISAG 351 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNR-HYYSYIPFSAGPRSCVGRKYAXX 453 + ++I + +HR P+Y+ DP F P+ + +N N+ Y Y PF GPR C+G ++A Sbjct: 352 SEIMISQWGMHRNPRYFNDPLTFLPERW--DNNDNKPSKYVYFPFGGGPRVCIGERFALM 409 Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 R FR + + E K++ I L+ G MK+ R Sbjct: 410 EATLIMATIVREFR-MELVDELPIKMEPSITLRPKHGVTMKLRKR 453 >UniRef50_UPI0001555B83 Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily V, polypeptide 2, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily V, polypeptide 2, partial - Ornithorhynchus anatinus Length = 412 Score = 138 bits (335), Expect = 2e-31 Identities = 66/184 (35%), Positives = 110/184 (59%), Gaps = 1/184 (0%) Query: 32 RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMI 91 ++W+G +V L A+ +E+IL+S I K+ YRF +PWLG GLL S+G KWRS RKM+ Sbjct: 142 KLWIGPVPMVILYHAESVEVILSSSKQISKSYVYRFLEPWLGLGLLTSTGGKWRSRRKML 201 Query: 92 APTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRK 150 PTFH +IL+ FVG+ N+++ +VEK + V + FD ++ +DI+ ETAMG + + Sbjct: 202 TPTFHFSILEEFVGVMNEHAQTLVEKFEKHVDRDAFDCFMDITLCALDIICETAMGRNIQ 261 Query: 151 TQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIK 210 Q +Y + +M D+I +R W+ + + L ++ + L ++H T++VI Sbjct: 262 VQTNGDSEYVRTIYRMSDLIQRRILMPWLWLDPCYLLFQEGREHRQKLRVLHEFTDRVIA 321 Query: 211 NKKE 214 + + Sbjct: 322 ERSK 325 Score = 81.0 bits (191), Expect = 7e-14 Identities = 38/69 (55%), Positives = 51/69 (73%) Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330 +R AFLDL++E++ + N +S +++EEVDT MFEGHDTTAA SFVL LLG D Q + Sbjct: 344 RRRAFLDLLLETADDARNGLSLRDVREEVDTFMFEGHDTTAAAMSFVLYLLGSCPDAQRK 403 Query: 331 VYDELYQIF 339 V DEL ++F Sbjct: 404 VNDELDRVF 412 >UniRef50_UPI0000D56468 Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 421 Score = 138 bits (335), Expect = 2e-31 Identities = 63/156 (40%), Positives = 103/156 (66%), Gaps = 2/156 (1%) Query: 292 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADT 351 D +++E+ I+ G +++A + VL +LGI+ +VQ ++ EL IFGD +R TF Sbjct: 266 DSPVEDEIQNILITGSESSALALALVLVVLGIYPEVQQKIALELDSIFGDDEREPTFEHI 325 Query: 352 LEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY 411 +M+YLE VI E+LR+ P VP+I R +D+ + ++ IPAG+TV++ + ++ +++ Sbjct: 326 NQMEYLECVIKETLRILPIVPIIMRLAEQDIKL--EHCTIPAGSTVLVPIVHISKKSEFW 383 Query: 412 KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447 K+P FNPD FLP+N RH +++PFS GPR+CVG Sbjct: 384 KEPNKFNPDRFLPKNNSERHRCTFLPFSYGPRNCVG 419 Score = 79.0 bits (186), Expect = 3e-13 Identities = 53/189 (28%), Positives = 92/189 (48%), Gaps = 15/189 (7%) Query: 25 QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKW 84 +T+ + + WLG LIV +D+EI+LNS +K Y++ GLLI+ W Sbjct: 70 ETYPTLSKFWLGKDLIVITSRPEDVEIVLNSC--FEKPKFYKYAYKLFRTGLLIAPVNIW 127 Query: 85 RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETA 144 + R+MI PTF+ L++F IF + +N +V L+ E G+ FD+ + T+D TA Sbjct: 128 KERRRMIGPTFNSKTLQTFTEIFGKQANRLVRVLEQECGREFDIFLKLFRCTLD----TA 183 Query: 145 MGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGL 204 G QD +Y +++ DI R + W++ + +K + ++ K Sbjct: 184 CG-----QD----NYLQKLIRAEDIATIRSFSPWLQVDFFWKKSPLGREMDKACAESFTF 234 Query: 205 TNKVIKNKK 213 +++ KK Sbjct: 235 IKQILSLKK 243 >UniRef50_Q3IR83 Cluster: Unspecific monooxygenase; n=1; Natronomonas pharaonis DSM 2160|Rep: Unspecific monooxygenase - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 448 Score = 138 bits (334), Expect = 3e-31 Identities = 83/275 (30%), Positives = 137/275 (49%), Gaps = 14/275 (5%) Query: 224 IIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESS 283 ++P + T E A + LS+ + + R+ L + D + L ++I + Sbjct: 183 VLPDWVPTPTSGEFEQAAAGIRELSEQLIERRRESLAAGERPDASD-----MLTMLIRAE 237 Query: 284 QNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD 343 N +++I++EV T + GH+TTA ++ LCLL H + + RV E + GD Sbjct: 238 DNPDIDYPENQIRDEVATFLIAGHETTALSLTYTLCLLSWHPEARRRVRQEADEALGDG- 296 Query: 344 RPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFM 403 P T D E+ Y RV E+LRLYPP + R+ N DVT+ Y IP G+ V++ + Sbjct: 297 -PPTHDDLAELTYTRRVYDEALRLYPPAWGVFRQANGDVTLG--QYTIPDGSAVIMPLWS 353 Query: 404 LHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXX 463 +HR Y++ P+ F+PD + E R +Y PFS+GP +C+GR +A Sbjct: 354 IHRDGSYFEQPDTFDPDRW--ERRTPRAVDAYRPFSSGPHACIGRGFALAGSTLVLARLV 411 Query: 464 RNFRTISEIPEKEF-KLQGDIILKRAEGFQMKVEP 497 R+F ++PE L+ L+ A+G + ++P Sbjct: 412 RDFDI--DVPESALDDLRLTPTLRPADGVEATIQP 444 Score = 34.3 bits (75), Expect = 7.7 Identities = 21/89 (23%), Positives = 38/89 (42%) Query: 75 GLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSG 134 GL+ S G W R ++AP+F + ++ + ++ + +T D+H M+ Sbjct: 83 GLVQSEGALWSQQRSVMAPSFSGEQVTAYANTTGRRIEARADQWAAAGARTTDLHREMTS 142 Query: 135 TTVDILLETAMGISRKTQDESGFDYAMAV 163 TV + E +G T+ F M V Sbjct: 143 LTVRVASEILLGEDIGTERADQFHEWMQV 171 >UniRef50_Q82D73 Cluster: Putative cytochrome P450; n=2; Streptomyces avermitilis|Rep: Putative cytochrome P450 - Streptomyces avermitilis Length = 470 Score = 136 bits (329), Expect = 1e-30 Identities = 77/241 (31%), Positives = 116/241 (48%), Gaps = 4/241 (1%) Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 +E D GE+ + L++ + + E++E+V + GH+TTA +F L LL Sbjct: 230 NEGDGGEESGEDLVTLLVRAGNAEDGSLDAAELREQVLIFLLAGHETTATALAFALHLLA 289 Query: 323 IHQDVQARVYDELYQIFGD-SDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381 H + Q RV DE ++ G R T AD + YL V+ E++RLYP PVI R+ D Sbjct: 290 RHPEQQRRVRDEADRVLGGPGGRAPTAADMEALPYLTMVLKEAMRLYPSAPVIGRRAVAD 349 Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441 + IPAG + + ++ HR P Y+ DPE F+P+ F PE R Y++ PF G Sbjct: 350 AEVDGVR--IPAGADLFVSPWVTHRHPDYWPDPERFDPERFTPEAEAGRPRYAWFPFGGG 407 Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRV 501 PR+C+G+ + R F + E+E L I L + +V PR Sbjct: 408 PRACIGQHLSMLESVLGLAVLIREFE-FEAVGEEEVPLGAGITLLAKGPARCRVIPRSSG 466 Query: 502 P 502 P Sbjct: 467 P 467 >UniRef50_UPI0000D55FA3 Cluster: PREDICTED: similar to Cytochrome P450 4g15 (CYPIVG15); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4g15 (CYPIVG15) - Tribolium castaneum Length = 193 Score = 136 bits (328), Expect = 2e-30 Identities = 68/169 (40%), Positives = 96/169 (56%), Gaps = 2/169 (1%) Query: 302 IMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVI 361 ++F G + A +VL +L IH ++Q ++Y+EL IFG+SDR F D ++ YL+RVI Sbjct: 1 MVFTGSGSLAITECYVLLMLAIHPEIQEKIYEELLTIFGNSDRDLCFKDLSKLCYLDRVI 60 Query: 362 LESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDN 421 E+LRL+P P IAR L+ D I + YVIP GT +I L R + +P F+PD Sbjct: 61 KETLRLFPIAPYIARLLDSD--IHMEKYVIPKGTFALIPITYLQRNSNLWSEPLRFDPDR 118 Query: 422 FLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTIS 470 FLPE R Y+PFS G R+C+G KYA R ++ +S Sbjct: 119 FLPEQVATRERCVYLPFSYGSRNCIGLKYAEISLKATLATILRKYKYVS 167 >UniRef50_Q6SPQ5 Cluster: CYP342A1; n=1; Nereis virens|Rep: CYP342A1 - Nereis virens (Sandworm) Length = 508 Score = 136 bits (328), Expect = 2e-30 Identities = 67/168 (39%), Positives = 106/168 (63%), Gaps = 5/168 (2%) Query: 287 TNKIS-DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDR 344 T K+ D EI++EVDT MFEGHDTTA+G S++L L H +VQ + E+ ++ G SD Sbjct: 322 TEKVCLDREIRDEVDTFMFEGHDTTASGISWILYELSGHPEVQEQAGQEVIRVIGSQSDG 381 Query: 345 PATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFML 404 ++D + YL + I E++R++PPVP I R+L++D+ I+ IP T + + + Sbjct: 382 TIEWSDLSRLPYLSQCIKEAMRVHPPVPFIGRQLSQDIIIN--GCTIPKDTICEVSIYGV 439 Query: 405 HRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 H P+ + KD F P+ F P+N +++ + YIPFSAG R+C+G+ +A Sbjct: 440 HHNPEVWGKDHMEFKPERFHPDNMKDKDAFDYIPFSAGSRNCIGQNFA 487 Score = 46.0 bits (104), Expect = 0.002 Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 1/46 (2%) Query: 52 ILNSHVHIDKATEYRFF-KPWLGEGLLISSGPKWRSHRKMIAPTFH 96 ++ + VH+ + K WLG+GLL+SSG KW +R+++ P FH Sbjct: 127 VIRTKVHLHRIWPVMLLLKEWLGDGLLLSSGSKWFRNRRLLTPAFH 172 >UniRef50_Q4U3Y5 Cluster: CYP325D1; n=1; Anopheles gambiae|Rep: CYP325D1 - Anopheles gambiae (African malaria mosquito) Length = 304 Score = 134 bits (323), Expect = 7e-30 Identities = 69/179 (38%), Positives = 107/179 (59%), Gaps = 5/179 (2%) Query: 274 AFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYD 333 A LD ++ +++G +SD EI + + +I+ G+DTTA L +H VQ ++Y Sbjct: 125 AMLDRLLSVNEDGP--LSDTEIVQNIYSIVGAGNDTTAHSLGHTCLFLAMHPAVQRKLYQ 182 Query: 334 ELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPA 393 EL +F +D P T ++ Y+E VI ESLRL PP +AR+ D+T+ + +IP Sbjct: 183 ELRDVFYSADEPITEEKLKQLSYMECVIKESLRLAPPGATVAREAQEDLTV--EGQLIPR 240 Query: 394 GTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 GTTVV+ F LHR+ ++ D E F+PD FL E +NR +++PF+ G R+C+G +YA Sbjct: 241 GTTVVVSLFALHRRKDFWGADAERFDPDRFLSERCKNRMGCAFMPFNTGSRNCIGSRYA 299 >UniRef50_Q4STK8 Cluster: Chromosome undetermined SCAF14158, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF14158, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 612 Score = 133 bits (322), Expect = 9e-30 Identities = 100/389 (25%), Positives = 181/389 (46%), Gaps = 18/389 (4%) Query: 76 LLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYM 132 LL+S+G W R+++ P FH +ILK++V FN ++N + +K L +E + + + Sbjct: 174 LLLSNGEVWLRKRRLLTPAFHFDILKNYVAKFNTSTNTMHDKWRRLAAEGPTHVEAFEDV 233 Query: 133 SGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFK 192 + T+D LL+ A Q S +YA A++++ D+I +R + + ++ T K Sbjct: 234 TLMTLDSLLKCAFSYDSDCQQSSS-EYASAIVQLSDLIIERRQRILHHWDWIYWRTRQGK 292 Query: 193 QQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVF 252 + + L I+H T V++ ++ T + K + + ++F + K L+D Sbjct: 293 RFQQALSIVHKFTRDVVQERR-TLIGQKGE-MAAQGKKDFVDIILLSKDEDGKGLTDEEI 350 Query: 253 KGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTN---KISDHEIKEEVDTIMFEGHDT 309 + + F E + K L + + S N ++ + + GHDT Sbjct: 351 QAEANTFMFAGEQWLMLK--LVDVSSNLTSGTRSVNLVLRLGSSCSQMSLSACSPTGHDT 408 Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD-RPATFADTLEMKYLERVILESLRLY 368 TA+ + L L H Q + E+ + D + D + + I ESLRL+ Sbjct: 409 TASAICWSLYNLARHDHYQEKCRKEVMDLMEGRDVHEINWEDLSSLPFTTMCIRESLRLH 468 Query: 369 PPVPVIARKLNRDVTIS---TKNYVI---PAGTTVVIGTFMLHRQPKYYKDPEVFNPDNF 422 PV + R+ +DV + TKN I P G ++ + H P + +P F+P F Sbjct: 469 SPVQAVTRRYLQDVELPGGHTKNETIACYPEGAICLVSIYGTHHNPAVWTNPHDFDPLRF 528 Query: 423 LPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 P N + +++IPFS+GPR+C+G+K+A Sbjct: 529 DPTNQKGLSSHAFIPFSSGPRNCIGQKFA 557 >UniRef50_A7SJV6 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 512 Score = 133 bits (322), Expect = 9e-30 Identities = 72/213 (33%), Positives = 113/213 (53%), Gaps = 5/213 (2%) Query: 288 NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPAT 347 NK+SD EI + T + G++TT+ +F LL ++ D Q R+ +E+ ++ Sbjct: 303 NKLSDDEIVAQCFTFILAGYETTSNTMAFTSYLLALNPDKQDRLIEEIDEVAATVGDNFD 362 Query: 348 FADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ 407 + L M+YLE V+ E+LRLYPP R N+ TI+ + + P G V+I F +HR Sbjct: 363 YDTVLGMEYLEMVVQEALRLYPPGFRFGRTCNQSCTINGQFF--PKGCIVLIPVFAMHRD 420 Query: 408 PKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467 P+ + +PE F P+ F E Q RH Y+++PF GPR+C+G ++A R +R Sbjct: 421 PEIWPEPEKFQPERFTAEAKQARHPYAHLPFGGGPRNCIGMRFALLEAKMALVYILRYYR 480 Query: 468 TISEIPEKE--FKLQGDIILKRAEGFQMKVEPR 498 + PE E +LQG I + G +K+ R Sbjct: 481 -LERCPETEVPVQLQGTITISPKHGIYLKITKR 512 Score = 45.6 bits (103), Expect = 0.003 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 4/132 (3%) Query: 25 QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVH--IDKATEYRFFKPWLGEGLLISSGP 82 +T+G + ++G++ + + D + + IL +++ P + LL Sbjct: 75 KTYGRLCGYYMGTRAAILVADPEMAKQILVKEFDKFVNRPIVQSAQTPPTDKTLLSLQDD 134 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDIL 140 WR R I PTF LK + + N++ +VEKL + GK+ DV T++ + Sbjct: 135 DWRRLRHTITPTFSAVKLKQVLPLINESCRILVEKLGEACKDGKSVDVLRSYGKFTMETI 194 Query: 141 LETAMGISRKTQ 152 + TA GI +TQ Sbjct: 195 VTTAFGIDCQTQ 206 >UniRef50_Q98T91 Cluster: Cytochrome P450 3A40; n=16; Euteleostomi|Rep: Cytochrome P450 3A40 - Oryzias latipes (Medaka fish) (Japanese ricefish) Length = 502 Score = 133 bits (321), Expect = 1e-29 Identities = 79/245 (32%), Positives = 128/245 (52%), Gaps = 14/245 (5%) Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKI-----SDHEIKEEVDTIMFEGHDTTAAGSSF 316 N EN+ +K R+ FL LMI+S +N N + SDHEI + +F G++TT++ +F Sbjct: 259 NHENNK-QKSRIDFLQLMIDSQKNNQNGLQDKGLSDHEILSQAMIFIFAGYETTSSSLTF 317 Query: 317 VLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIAR 376 + L + +V ++ E+ F + P + +EM+YL+ V+ ESLRLYP IA Sbjct: 318 LAYNLATNPEVMKKLQKEIDATFPNK-APVQYVPLMEMEYLDCVVNESLRLYP----IAA 372 Query: 377 KLNR--DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434 +L R T+ VIP V++ T+ LHR P+ + +PE F P+ F EN Y+ Sbjct: 373 RLERVAKATVEVNGLVIPKDMVVMVPTWPLHRDPELWPEPEKFKPERFSKENKDTFDPYT 432 Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQGDIILKRAEGFQM 493 Y+PF AGPR+C+G ++A + + ++ + E F++ L Q+ Sbjct: 433 YMPFGAGPRNCIGMRFALVMMKLAVVEILQTYDFSVCKETEVPFEMDVQGFLAPKRPIQL 492 Query: 494 KVEPR 498 K+ PR Sbjct: 493 KLTPR 497 Score = 43.6 bits (98), Expect = 0.013 Identities = 27/144 (18%), Positives = 65/144 (45%), Gaps = 5/144 (3%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVH--IDKATEYRFFKPWLGEGLLISSGPKW 84 +G ++ G + ++ + D I+ +L + +R P L + + I+ +W Sbjct: 68 YGKTWGIYDGRQPVLCITDPATIKAVLVKECYSLFTNRRNFRLNGP-LYDAVSIAEDDQW 126 Query: 85 RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLE 142 + R +++P+F LK I +S N+++ +K +V K ++ +Y ++D++ Sbjct: 127 KRIRSVLSPSFTSGRLKEMFDIMKHHSANLIQSMKKKVDKDEPLEMKEYFGPYSMDVVTS 186 Query: 143 TAMGISRKTQDESGFDYAMAVMKM 166 TA + + + + + KM Sbjct: 187 TAFSVDIDSLNNPSDPFVTNIKKM 210 >UniRef50_Q6PH32 Cluster: Cytochrome P450, family 4; n=7; Clupeocephala|Rep: Cytochrome P450, family 4 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 458 Score = 132 bits (320), Expect = 2e-29 Identities = 69/194 (35%), Positives = 110/194 (56%), Gaps = 3/194 (1%) Query: 251 VFKGYRDDLDFNDENDVGEKKR-LAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDT 309 V + ++ L +E + + +R L FLD+++ + +SD +I+ EVDT MFEGHDT Sbjct: 261 VIRKRKEVLKMEEEQGIVKNRRYLDFLDILLSARDEHQQGLSDEDIRAEVDTFMFEGHDT 320 Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYP 369 TA+G S++ L + + Q + E+ Q D + D ++ Y I ESLRL+P Sbjct: 321 TASGISWIFYNLACNPEHQEKCRQEIQQALDGKD-TLEWEDLNKIPYTTMCIKESLRLHP 379 Query: 370 PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQN 429 PVP I+RKL + +T +P G T+ + + +H +++P F+P FLPEN N Sbjct: 380 PVPGISRKLTKPLTF-FDGRTVPEGCTIGVSIYGIHMNSTVWENPYKFDPLRFLPENAAN 438 Query: 430 RHYYSYIPFSAGPR 443 R ++++PFSAGPR Sbjct: 439 RSPHAFVPFSAGPR 452 Score = 105 bits (253), Expect = 2e-21 Identities = 55/196 (28%), Positives = 104/196 (53%), Gaps = 3/196 (1%) Query: 33 VWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIA 92 +W G L V + + + Y+FF PWLG+GLL+S+G KW HR+++ Sbjct: 83 LWFGPSLAVLNIHHPSYAKTILTTTEPKDDYAYKFFIPWLGDGLLVSTGQKWFRHRRLLT 142 Query: 93 PTFHINILKSFVGIFNQNSNNVVEK--LKSEVGKTFDVHDYMSGTTVDILLETAMGISRK 150 P FH ++LK +V + + ++ +++K + S ++F++ ++S T+D +++ A + Sbjct: 143 PGFHYDVLKPYVKLISDSTKVMLDKWEVHSRSEESFELFKHVSLMTLDSIMKCAFSCNSN 202 Query: 151 TQDESGFD-YAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVI 209 Q +SG + Y AV +C +++ R F S+ +F L+ + K I H T +VI Sbjct: 203 CQTDSGTNPYIQAVFDLCHLVNLRFRVFPYHSKAIFHLSPHGYRFRKAASIAHNHTAEVI 262 Query: 210 KNKKETYLENKAKGII 225 + +KE + +GI+ Sbjct: 263 RKRKEVLKMEEEQGIV 278 >UniRef50_Q3L917 Cluster: Cytochrome P450; n=1; Rhodococcus erythropolis PR4|Rep: Cytochrome P450 - Rhodococcus erythropolis (strain PR4) Length = 510 Score = 132 bits (320), Expect = 2e-29 Identities = 77/224 (34%), Positives = 120/224 (53%), Gaps = 6/224 (2%) Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 LDLM+ S+ T K+ I+ +V T + G++TTA +F L L H DV E Sbjct: 292 LDLMLHSADAETGEKLDPVNIRNQVFTFLVAGNETTAGTLAFALYFLSRHPDVADTARAE 351 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + + + PA F D M+YL RV+ E+LRL+P P RK+ D T+ + Y +P G Sbjct: 352 VADVTA-GETPA-FEDVARMRYLRRVVDETLRLWPSAPGYFRKVRTDTTLGGR-YDMPKG 408 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454 + V + LHR P + +DPE F+PD F PEN + R ++Y PF GPR+C+GR++A Sbjct: 409 SWVFVLLPQLHRDPVWGEDPESFDPDRFKPENVKKRPAHAYRPFGTGPRACIGRQFALHE 468 Query: 455 XXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 + + S+ PE + ++ + LK GF++ ++ R Sbjct: 469 AVLALAIILQRYNFQSD-PEYKLDIRETLSLKPV-GFELSLQRR 510 >UniRef50_P05184 Cluster: Cytochrome P450 3A3; n=159; Euteleostomi|Rep: Cytochrome P450 3A3 - Homo sapiens (Human) Length = 504 Score = 132 bits (318), Expect = 3e-29 Identities = 77/237 (32%), Positives = 128/237 (54%), Gaps = 11/237 (4%) Query: 269 EKKRLAFLDLMIESSQNGTNK-----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323 +K R+ FL LMI+S +N +SD E+ + +F G++TT++ SF++ L Sbjct: 265 QKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELAT 324 Query: 324 HQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383 H DVQ ++ +E+ + + P T+ L+M+YL+ V+ E+LRL+P + R +DV Sbjct: 325 HPDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVE 383 Query: 384 ISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443 I+ IP G V+I ++ LHR PKY+ +PE F P+ F +N N Y Y PF +GPR Sbjct: 384 IN--GMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 441 Query: 444 SCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDI--ILKRAEGFQMKVEPR 498 +C+G ++A +NF + E + L+ + +L+ + +KVE R Sbjct: 442 NCIGMRFALMNMKLALIRVLQNF-SFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 497 Score = 44.8 bits (101), Expect = 0.005 Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 5/126 (3%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKP--WLGEGLLISSGPKW 84 +G V + G + ++ + D D I+++L + T F P ++ + I+ +W Sbjct: 68 YGKVWGFYDGQQPVLAITDPDMIKLVLVKECY-SVFTNREPFGPVGFMKSAISIAEDEEW 126 Query: 85 RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLE 142 + R +++PTF LK V I Q + +V L+ E GK + D ++D++ Sbjct: 127 KRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITS 186 Query: 143 TAMGIS 148 ++ G++ Sbjct: 187 SSFGVN 192 >UniRef50_A7D7T8 Cluster: Cytochrome P450; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Cytochrome P450 - Halorubrum lacusprofundi ATCC 49239 Length = 469 Score = 131 bits (316), Expect = 5e-29 Identities = 63/176 (35%), Positives = 101/176 (57%), Gaps = 6/176 (3%) Query: 276 LDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDEL 335 L +++ + G +D +++E+ T++ GHDTTA ++ LL H + + RV E Sbjct: 255 LSVLLRARDRGEQ--TDENLRDELVTMLLAGHDTTALALTYTFYLLSNHPEARERVAREA 312 Query: 336 YQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGT 395 +D P T AD EMK+ ERV+ ESLRLYPPV + R+ DV + Y IP G+ Sbjct: 313 AA--ATADGPPTAADAREMKFTERVLNESLRLYPPVYTLFREPKLDVKLG--GYRIPEGS 368 Query: 396 TVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 +++ + +HR P++Y DPE F+P + PE R +++ PF GPR C+G+ ++ Sbjct: 369 ALMLSQWAIHRSPRWYDDPETFDPSRWEPERQSKRPRFAFFPFGGGPRHCIGKAFS 424 Score = 48.4 bits (110), Expect = 4e-04 Identities = 30/125 (24%), Positives = 59/125 (47%), Gaps = 4/125 (3%) Query: 24 AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYR--FFKPWLGEGLLISSG 81 A ++G+V+R LG + L + D+E +L + + ++ LG GLL+S G Sbjct: 32 ADSYGDVVRFDLGPRETYMLTNPADVERVLVADAERYRKPDFGDDAIDTLLGNGLLMSEG 91 Query: 82 PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILL 141 W R++ +P+FH + + G +++ + + G+ DV ++ TV I++ Sbjct: 92 ETWERQRRLASPSFHSRRIGALAGTMVEHTESQLADWAD--GEVVDVQLEVARLTVKIIV 149 Query: 142 ETAMG 146 G Sbjct: 150 SAMFG 154 >UniRef50_Q8WQN9 Cluster: Cytochrome P450 CYP4J5; n=22; Endopterygota|Rep: Cytochrome P450 CYP4J5 - Anopheles gambiae (African malaria mosquito) Length = 153 Score = 130 bits (315), Expect = 6e-29 Identities = 66/154 (42%), Positives = 90/154 (58%), Gaps = 4/154 (2%) Query: 298 EVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA---DTLEM 354 EVDT MFEGHDTT + F+L L ++Q R++ EL Q+ +D D Sbjct: 1 EVDTFMFEGHDTTGSALVFILLTLSWELEIQTRLHQELSQLATQNDLTDGHLSPNDLNSA 60 Query: 355 KYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDP 414 K+ +RVI E LRL+PPV I+R + ++ + +IP G + F LHR P + DP Sbjct: 61 KFFDRVIKECLRLWPPVAFISRSVTEEIHLPDGR-IIPQGCIANLHIFDLHRDPAQFPDP 119 Query: 415 EVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 E F+PD FLPE R Y+YIPFSAGPR+C+G+ Sbjct: 120 ERFDPDRFLPECVSQRSPYAYIPFSAGPRNCIGQ 153 >UniRef50_Q095M8 Cluster: Cytochrome P450 4A5; n=1; Stigmatella aurantiaca DW4/3-1|Rep: Cytochrome P450 4A5 - Stigmatella aurantiaca DW4/3-1 Length = 374 Score = 130 bits (314), Expect = 8e-29 Identities = 71/230 (30%), Positives = 117/230 (50%), Gaps = 5/230 (2%) Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328 ++K L + + + G +SD +++ E+ + GHDTTA G +F LL H + Sbjct: 150 DRKDLLAMYMSAVDEETGEG-MSDEQLRHELMNLFLAGHDTTANGLAFTFYLLSKHPEAL 208 Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 RV +E + G+ R T D ++ Y E+LR+YPP ++R R+ + + Sbjct: 209 KRVDEERDAVLGNG-RMVTNEDLPQLNYARWSFEEALRIYPPTFAMSRTSVRE--LKHND 265 Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 YVIPAG+ + + + LHR P+ + +P+ F P+ F PE ++ RH ++Y+PF AGPR C+G Sbjct: 266 YVIPAGSNIFVCQWALHRNPRLWPNPDHFEPERFSPERSEGRHRFAYLPFGAGPRICIGA 325 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 A + FR SE P E +L + + G M++ R Sbjct: 326 HLARTEAQMIIAMLLQRFRLNSE-PGYEPRLVARLFVTAEPGISMRLSRR 374 Score = 42.3 bits (95), Expect = 0.029 Identities = 22/72 (30%), Positives = 35/72 (48%) Query: 70 PWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVH 129 P +G GL SG W+ R+M P F + +F GI + + + ++ G+T DV Sbjct: 6 PAIGAGLSTLSGDPWKRQRRMANPAFSRASIATFEGIMQKAIAEAIVEWEARAGETIDVT 65 Query: 130 DYMSGTTVDILL 141 M T+ I+L Sbjct: 66 GEMKRLTLRIVL 77 >UniRef50_A7DM29 Cluster: Cytochrome P450; n=2; Methylobacterium extorquens PA1|Rep: Cytochrome P450 - Methylobacterium extorquens PA1 Length = 471 Score = 130 bits (313), Expect = 1e-28 Identities = 77/227 (33%), Positives = 123/227 (54%), Gaps = 14/227 (6%) Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 L L++++ T ++SD + + + T + GH+TTA + L +L H V+AR+ DE Sbjct: 252 LGLLLQAKDPETGERLSDESLIDNLLTFVAAGHETTALALIWTLRVLADHPAVEARILDE 311 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + + D PA A + + +V+LE +RLYPP P+I R+ +V + + VIPAG Sbjct: 312 IAGLGAD---PAPEALD-RLAFTRQVVLEVMRLYPPAPLIVRRTAEEVRLG--DMVIPAG 365 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454 +V + + LHR ++ P+VF+PD F PE T +R Y+Y+PF AGPR C+G A Sbjct: 366 ESVHVPVYALHRHQSLWERPDVFDPDRFAPELTASRDRYAYLPFGAGPRVCIGMGLALTE 425 Query: 455 XXXXXXXXXRNFRTI---SEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 FR + +E+P +F+ + L+ G +MKV PR Sbjct: 426 CLVILATLLPAFRFVPAKAEMPATQFR----VTLRPKGGMKMKVVPR 468 Score = 39.5 bits (88), Expect = 0.20 Identities = 16/39 (41%), Positives = 23/39 (58%) Query: 66 RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFV 104 R P LG G+L + GP WR R+ AP F + +K+F+ Sbjct: 89 RALAPALGSGILTADGPHWRGQRRTAAPMFRPDRVKAFI 127 >UniRef50_Q3I414 Cluster: Cytochrome P450; n=18; Cucujiformia|Rep: Cytochrome P450 - Leptinotarsa decemlineata (Colorado potato beetle) Length = 510 Score = 129 bits (312), Expect = 1e-28 Identities = 67/211 (31%), Positives = 109/211 (51%), Gaps = 2/211 (0%) Query: 281 ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG 340 E + +GT+ D EI + G +T++ +F L L H ++Q +V E+ + Sbjct: 290 EHTGDGTSLTMD-EIVAQSFVFFIAGFETSSTTMTFALYQLATHPEIQEKVRSEINSVLE 348 Query: 341 DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIG 400 + T+ E+KY+ +VI E+LR+YP +PV+ R+ D I + +I G V I Sbjct: 349 KHNNQITYDALNELKYMGKVIDETLRMYPALPVVTRRCVEDYRIPDSDVIIEKGIEVFIP 408 Query: 401 TFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXX 460 +H P+YY++PEVF+P+ F EN Q RH Y++IPF GPR C+G ++ Sbjct: 409 IKAIHYDPEYYENPEVFDPERFNEENIQGRHPYAHIPFGEGPRICIGLRFGVMQSKVGLV 468 Query: 461 XXXRNFR-TISEIPEKEFKLQGDIILKRAEG 490 +NFR T+S + K+ + + EG Sbjct: 469 SILKNFRVTLSSKTKLPLKIDVNSFIPTTEG 499 >UniRef50_Q177R7 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 496 Score = 128 bits (308), Expect = 5e-28 Identities = 73/241 (30%), Positives = 128/241 (53%), Gaps = 7/241 (2%) Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVD---TIMFEGHDTTAAGSSFVL 318 NDE D + K F I +Q TN I E +E +D TI+ G DT+A +F Sbjct: 258 NDETD--DDKTEGFRKPQIFVNQIFTNTIRKFERQEIIDNIITIVGAGTDTSATAIAFTF 315 Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKL 378 L ++Q+ Q +VY+E+ ++F +S+ T +++Y + V+ E LRLYP P++ R+ Sbjct: 316 LQLAMYQEHQQKVYEEIVKVFPESEPHITTEALKKLQYTKMVLNECLRLYPVAPILLREN 375 Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIP 437 D+T+ +P G + I + +HR+ + D + F P+ F PE + RH ++++ Sbjct: 376 TADITL-CGGVRVPKGNILTIDVYNIHRRKDVWGPDADEFIPERFSPERSAGRHPFAFLT 434 Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 FS G R+C+G +YA +NFR ++I E++ + + D +L+ G +++E Sbjct: 435 FSGGSRNCIGSRYAMISMKIMMVYLLKNFRFKTKIREEDIRYKFDALLRIEGGHLVQIEK 494 Query: 498 R 498 R Sbjct: 495 R 495 Score = 68.5 bits (160), Expect = 4e-10 Identities = 42/170 (24%), Positives = 89/170 (52%), Gaps = 6/170 (3%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 + R++LG ++++ D + I+ ++K Y+FF L EG+ + W+ RK Sbjct: 68 LFRLYLGPRMLLCTSDPTVAQAIMTDANCMEKPYVYKFFN--LNEGVFAAKTHIWKGQRK 125 Query: 90 MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGI 147 + P F+ IL+SFV IF + S ++++L + VGK T ++ ++ S T++++ T +G Sbjct: 126 ALNPAFNSKILESFVSIFCEVSKTMIQRLDT-VGKGDTINIMEHASRCTLEMVCSTTLGF 184 Query: 148 SRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKL 197 + D+ + + + I +R KF++ + +++ T +K + L Sbjct: 185 NVDIFDQID-EMGHKIEQFFYIAARRILKFYLHVDSIYRWTKDYKDEQTL 233 >UniRef50_Q495Y1 Cluster: CYP3A43 protein; n=4; Homo sapiens|Rep: CYP3A43 protein - Homo sapiens (Human) Length = 393 Score = 128 bits (308), Expect = 5e-28 Identities = 66/202 (32%), Positives = 109/202 (53%), Gaps = 7/202 (3%) Query: 269 EKKRLAFLDLMIESSQNGTNK----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324 +K R+ F MI+S + K +SD E+ + I+F +DTT+ F++ L H Sbjct: 155 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 214 Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384 DVQ ++ +E+ + + P T+ ++M+YL+ V+ E+LRL+P V + R +D+ I Sbjct: 215 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 273 Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRS 444 + IP G V++ + LH PKY+ +PE F P+ F +N + Y YIPF AGPR+ Sbjct: 274 N--GVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 331 Query: 445 CVGRKYAXXXXXXXXXXXXRNF 466 C+G ++A +NF Sbjct: 332 CIGMRFALTNIKLAVIRALQNF 353 >UniRef50_Q8WQN1 Cluster: Cytochrome P450 CYP4H24; n=23; Culicidae|Rep: Cytochrome P450 CYP4H24 - Anopheles gambiae (African malaria mosquito) Length = 193 Score = 127 bits (307), Expect = 6e-28 Identities = 67/191 (35%), Positives = 100/191 (52%), Gaps = 4/191 (2%) Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDR--PATFADTLEMKYLERVILESLRL 367 T +G SF L H ++Q ++Y E+ + G R P T+ YL+ V+ ESLRL Sbjct: 4 TTSGISFTFYQLAKHPEIQEKLYREIQDVLGGEYRHVPLTYNTLQNFPYLDMVVKESLRL 63 Query: 368 YPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENT 427 PPV I R+L D+ ++ IPAGT I +++HR P Y DPE F+P+ F NT Sbjct: 64 LPPVSFIGRRLADDIEMN--GVTIPAGTDFTIPIYVIHRNPVVYPDPERFDPERFSDGNT 121 Query: 428 QNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKR 487 Q R Y YIPFS G R+C+G++YA +R + E +L+ D++L+ Sbjct: 122 QRRGPYDYIPFSIGSRNCIGQRYALLEMKVAIVRMVSFYRILPGDTMHEIRLKTDLVLRP 181 Query: 488 AEGFQMKVEPR 498 + +K+ R Sbjct: 182 DKSIPIKLVAR 192 >UniRef50_Q8T632 Cluster: Cytochrome P450 CYP6P3; n=42; Diptera|Rep: Cytochrome P450 CYP6P3 - Anopheles gambiae (African malaria mosquito) Length = 509 Score = 127 bits (307), Expect = 6e-28 Identities = 71/225 (31%), Positives = 113/225 (50%), Gaps = 16/225 (7%) Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISD-------------HEIKEEVDTI 302 ++ +D+ + N+V KR F++LM++ G SD +E+ + Sbjct: 255 KETVDYREANNV---KRNDFMNLMLQIKNKGKLDDSDDGSLGKGEVGMTQNELAAQAFVF 311 Query: 303 MFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVIL 362 G +T++ SF L L + D+Q R+ +E+ + ++ T+ + +KYL+ VI Sbjct: 312 FLAGFETSSTTQSFCLYELAKNPDIQERLREEINRAIAENGGEVTYDVVMNIKYLDNVID 371 Query: 363 ESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNF 422 E+LR YPPV + R + D I +VIP T V I + + R P +Y DPE FNPD F Sbjct: 372 ETLRKYPPVESLTRVPSVDYLIPGTKHVIPKRTLVQIPAYAIQRDPDHYPDPERFNPDRF 431 Query: 423 LPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467 LPE + RH +++IPF GPR C+G ++ R FR Sbjct: 432 LPEEVKKRHPFTFIPFGEGPRICIGLRFGLMQTKVGLITLLRKFR 476 >UniRef50_Q16TD6 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 519 Score = 126 bits (305), Expect = 1e-27 Identities = 106/420 (25%), Positives = 184/420 (43%), Gaps = 41/420 (9%) Query: 72 LGEGLLISS-GPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDV 128 LG+GL+ G WR RK++ P F IL FV I + + +V+ L ++ FD+ Sbjct: 111 LGKGLITEQRGEIWRRSRKLLNPAFSTRILNEFVPIMDSRARKMVKSLAVLADDKTEFDI 170 Query: 129 HDYMSGTTVDILLETAMGISRKTQDESG-FDYAMAVMKMCDIIHQRHYKFWMRSEIVFKL 187 + T++++ T MG K ++ G +Y + + I +R V++ Sbjct: 171 LPITAQCTLEMVFSTTMGC--KMEERPGEREYVRCLEGLMTCIGERILNIDRYLGPVYRF 228 Query: 188 TSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTL 247 T ++ +G T K+I+ +K + N II + G + + N Sbjct: 229 TKAYQVDKVCRDTCNGFTEKIIQERKRE-MANINNNIIDERMSAAEIDDGRVKSMN---F 284 Query: 248 SDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGH 307 D + R D G F+D +++SDH + +I+ G+ Sbjct: 285 LDQILTIQRPD---------GTN----FVD----------DEVSDH-----LYSIVGAGN 316 Query: 308 DTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRL 367 +T+ S+ L + +QA+V E+ Q+F T ++ Y E + E+LRL Sbjct: 317 ETSTLTISYTCLFLAMDHQIQAKVCSEIKQVFPSHHTEVTPEALKQLIYTEMALKETLRL 376 Query: 368 YPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKD-PEVFNPDNFLPEN 426 P VP AR + + + IP F LHR+ ++ D PE F+P+ F PEN Sbjct: 377 CPAVPFAARSNVKPIELD--GIHIPQRQIFCFNFFALHRRKDFWGDEPEQFDPNRFSPEN 434 Query: 427 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486 ++NRH Y+Y+PFS G R+C+G +YA +NF + + ++ + + I +K Sbjct: 435 SRNRHPYAYLPFSGGFRNCIGGRYAINSLKIMLLRILQNFHMDTSLKREDMRFRWAITMK 494 >UniRef50_UPI0000D56467 Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 470 Score = 126 bits (304), Expect = 1e-27 Identities = 75/247 (30%), Positives = 131/247 (53%), Gaps = 13/247 (5%) Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319 DF D++ ++ FL+ +++ S+N T D +I EE T++ +TTA + VL Sbjct: 232 DFPDDS----MRKKHFLNNLLKMSENMT----DDDILEETQTMLVAASETTALTMATVLL 283 Query: 320 LLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLN 379 L I VQ ++Y+EL I ++D T +M YLE VI E++R+ P VP I R++ Sbjct: 284 TLAIFPQVQEKIYEELDAILWNTDE-ITLEHINKMVYLEAVIKETMRILPTVPFINRRMT 342 Query: 380 RDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFS 439 D+ ++ + V+P G+ ++I +H P +++P+ F+P+ FL E NR +++PF Sbjct: 343 EDLHLN--DCVVPTGSNIIISIKNIHDSPLLWENPDKFDPERFLTERDPNRSRCAFMPFG 400 Query: 440 AGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEK--EFKLQGDIILKRAEGFQMKVEP 497 GPR+C+G K+A +NF + + E + +I+ K +G+++K Sbjct: 401 YGPRNCIGFKFAMLSMKVMMASLLKNFTFEPAVYKSIAEIECFYNIVAKPKKGYKVKFSE 460 Query: 498 RKRVPTN 504 RK N Sbjct: 461 RKLYNNN 467 Score = 95.1 bits (226), Expect = 4e-18 Identities = 64/188 (34%), Positives = 91/188 (48%), Gaps = 10/188 (5%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 + ++WLG LI +D EIIL+ K F P EGLL + KW+SHRK Sbjct: 39 LFKIWLGQDLIFVTSRPEDCEIILSKC--FTKGKFATFMDPIFWEGLLTAPAIKWKSHRK 96 Query: 90 MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGIS 148 +I P+F+I IL SF+G+FN++S +VEK++ G + DV ++ T+DI ET M I Sbjct: 97 IINPSFNIQILNSFIGVFNKHSKKLVEKMRKHAGSDSVDVSYWLFRNTIDISCETLMDID 156 Query: 149 R---KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205 K Q+E Y +K R W E ++K + K I Sbjct: 157 ADLIKGQEE----YIDDCIKAEKYSSTRMIGVWYHPEFIWKHSPLGKLTKATSDKILDFV 212 Query: 206 NKVIKNKK 213 K+IK KK Sbjct: 213 RKIIKLKK 220 >UniRef50_Q06GC7 Cluster: Cytochrome P450; n=1; Rhodococcus sp. NS1|Rep: Cytochrome P450 - Rhodococcus sp. NS1 Length = 497 Score = 126 bits (304), Expect = 1e-27 Identities = 70/226 (30%), Positives = 117/226 (51%), Gaps = 8/226 (3%) Query: 276 LDLMIESSQNGTNKI-SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 L M+++ T ++ SD I+ +V T + GH+TTA SF L L ++ ++ R +E Sbjct: 274 LQRMLDNPDPETGEMMSDQSIRNQVLTFLIAGHETTAGLLSFALHYLSLNPEIVERAREE 333 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + Q+ G P F +++Y+ R+I E+LRL+P P RK + T+ Y I G Sbjct: 334 IEQVLGTDGAPVRFEQVAKLRYVRRIIDETLRLWPSGPAFFRKARQATTLD--GYPIRKG 391 Query: 395 TTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXX 453 T+++ LHR P + +DPE F+PD FLP + R ++Y PF G R+C+GR++A Sbjct: 392 ETILVVLLALHRDPALWGEDPERFDPDRFLPAAVRARPAHAYKPFGVGARACIGRQFALH 451 Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK-RAEGFQMKVEPR 498 F +P +++L + +L R E ++ + PR Sbjct: 452 EAVLALAQILTRF---DIVPTADYELTVEELLTIRPENLKLAMRPR 494 >UniRef50_UPI000038CC01 Cluster: COG2124: Cytochrome P450; n=1; Nostoc punctiforme PCC 73102|Rep: COG2124: Cytochrome P450 - Nostoc punctiforme PCC 73102 Length = 451 Score = 126 bits (303), Expect = 2e-27 Identities = 70/229 (30%), Positives = 118/229 (51%), Gaps = 5/229 (2%) Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327 GEK LM + ++ D +++EV T+M GH+TTA S+ LL + V Sbjct: 220 GEKTNDLLTMLMEAKDEQTLQQMDDKLLRDEVATLMLAGHETTANTLSWTWMLLAQNPGV 279 Query: 328 QARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387 + ++ EL Q+ + T D ++ Y +++I ES+RLYPPVP++ R+ D I Sbjct: 280 REKLESELNQVL--QGKLPTLEDLGQLVYTQQIIKESMRLYPPVPLMGREAAVDTQIG-- 335 Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447 +Y IP G ++I +++HR PKY+++PE F P+ + E + YIPF GPR C+G Sbjct: 336 DYEIPQGMAIMISQWVMHRHPKYFENPEAFQPERWTQEFEKQLPKGVYIPFGDGPRICIG 395 Query: 448 RKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496 + +A + F+ I +P Q I L+ G +++++ Sbjct: 396 KGFAQMEAALLLATIAQRFQ-IDLVPGYPIVPQPSITLRPENGLKVQLK 443 Score = 55.6 bits (128), Expect = 3e-06 Identities = 30/116 (25%), Positives = 58/116 (50%), Gaps = 2/116 (1%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86 +G+++ + LG +++ + IE +L + K+ R K LGEGLL + G W Sbjct: 37 YGDIVPLQLGLTPSCLIINPEYIEEVLKNRNDFIKSRGLRALKSLLGEGLLSAEGESWFW 96 Query: 87 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLE 142 R++ P FH + + + +N +V+ G+T D+H+ M T+ I+++ Sbjct: 97 QRRLAQPVFHQKRINGYSQTMVEYTNRMVQTWHD--GETHDIHEDMMRLTLQIVMK 150 >UniRef50_Q964R1 Cluster: Cytochrome P450 6j1; n=1; Blattella germanica|Rep: Cytochrome P450 6j1 - Blattella germanica (German cockroach) Length = 501 Score = 126 bits (303), Expect = 2e-27 Identities = 59/197 (29%), Positives = 102/197 (51%), Gaps = 1/197 (0%) Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329 +KR LD ++E + T+K+ + + + G T++ +F L L +HQD+Q Sbjct: 270 EKRNDLLDYLMELRTSETSKLDGDDFVAQAFGFLVAGFHTSSMTLTFALYELSVHQDIQT 329 Query: 330 RVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389 E+ + + T+ +MKYL+ V+ E+LR YP +P + R+ D + T++ Sbjct: 330 TARTEIKDVLEHHKKKVTYYSIKDMKYLDMVVNETLRKYPAIPFLDRRCQEDYPL-TQDL 388 Query: 390 VIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449 ++PAGT V I + LH KY+ P F+P+ F +N QN +++Y+PF GPR+C+G + Sbjct: 389 MLPAGTGVYIPVYALHHDSKYFPSPAKFDPERFSEKNKQNIPHFAYMPFGEGPRNCIGMR 448 Query: 450 YAXXXXXXXXXXXXRNF 466 + NF Sbjct: 449 FGSMQVKAALIHILSNF 465 >UniRef50_Q0IG08 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 526 Score = 125 bits (302), Expect = 2e-27 Identities = 106/421 (25%), Positives = 185/421 (43%), Gaps = 44/421 (10%) Query: 72 LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHD 130 LG GL+ G KWR R M++P F N ++ V + + + ++ ++ E + +DV + Sbjct: 116 LGNGLISLEGQKWRDMRAMLSPMFTGNKIRHMVPLVGKCAEDLCRFVERETDEVEWDVRE 175 Query: 131 YMSGTTVDILLETAMGISRKT--QDESGFD-YAMAVMKMCDIIHQRHYKFWMRSEIVFKL 187 ++ V+++ A GI + ++ FD A +M D+ R F L Sbjct: 176 LLAKCLVEVIGSCAFGIEVDSFNDPDNEFDRVAKYLMNQSDV----------RKVARFLL 225 Query: 188 TSFFKQQTKLLG--IIHGLTNKVIKNK-KETYLENKAKGIIPPTLEEFTHHSGEILANNA 244 F + K G + ++ + ET L+ ++ G+ P L + +LA Sbjct: 226 IMVFPKMCKQFGMELFDDKYKRLFRRLVSETMLKRESDGVSRPDLIQLL-----MLARRG 280 Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMF 304 K +D DV + A D + + + SD E+ + Sbjct: 281 KLEAD---------------KDVEGESFAAANDYLETGTDDVKRSWSDDELTAQAVIFFA 325 Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364 G DTT+ SF L L IH ++Q R+++E+ + SD ++ ++YL+ VI ES Sbjct: 326 AGFDTTSTLLSFTLMELAIHPEIQDRLFEEIKSV-QRSDSVISYEQIQSLEYLDAVISES 384 Query: 365 LRLYPPVPVIARKLNRDVTI-----STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNP 419 LR +PP+ RK +D + + + I G +V + + H PKY+ +PE F+P Sbjct: 385 LRKWPPLTATDRKCTKDYLMVDPEDGSPMFSIEEGYSVWVPIYCFHHDPKYFPNPEKFDP 444 Query: 420 DNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKL 479 D F N + +Y+PF GPR+C+G ++A R+FR + P+ + L Sbjct: 445 DRFNRVNRHQLNPAAYMPFGVGPRNCIGSRFALMSAKMILLRLLRSFR-VEVCPKTDTTL 503 Query: 480 Q 480 Q Sbjct: 504 Q 504 >UniRef50_UPI00015B4AC4 Cluster: PREDICTED: similar to cytochrome P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 521 Score = 124 bits (300), Expect = 4e-27 Identities = 62/209 (29%), Positives = 108/209 (51%), Gaps = 6/209 (2%) Query: 271 KRLAFLDLMIESSQNGT----NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326 KR F+DL+IE GT N + ++ I + G++T++ +F L L ++ + Sbjct: 286 KRHDFMDLLIELKNRGTLELDNVLDENTIAAQAFVFFVAGYETSSNTIAFCLYELAVNPE 345 Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386 +Q + ++ D T+ +MKYL+ VILE+LR YPP P+++R+ + Sbjct: 346 IQEKARRDIIDALDKRDSKLTYDAVQDMKYLDMVILETLRKYPPAPLLSRRCEYPYKLPG 405 Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446 + + G VVI + +H PK+Y +P+ F P+ F E + RH Y+++PF GPR+C+ Sbjct: 406 SDVELSKGMRVVIPIYAIHHDPKHYPEPDKFRPERFGDEEKRARHPYTFLPFGEGPRNCI 465 Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEK 475 G ++A R ++ E+ EK Sbjct: 466 GTRFALLQTKVGVITFLRKYQV--EVCEK 492 >UniRef50_A3RK60 Cluster: Cytochrome P450; n=2; Liposcelis bostrychophila|Rep: Cytochrome P450 - Liposcelis bostrychophila Length = 527 Score = 124 bits (299), Expect = 6e-27 Identities = 102/384 (26%), Positives = 170/384 (44%), Gaps = 31/384 (8%) Query: 72 LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK-SEVGKTF-DVH 129 L L SG KWR+ R + PTF +K I ++ ++ L+ + + K ++ Sbjct: 121 LSAHLFSISGSKWRNLRAKLTPTFTSGKMKMMFPILVESGREMISILEPNAINKDIVEMK 180 Query: 130 DYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTS 189 D ++ T D++ A GI + ++ KM I + + +R+ S Sbjct: 181 DILARFTTDVIASCAFGIDSNSLKNPDTEFR----KMGRKIVEPSFANILRN------FS 230 Query: 190 FFKQQTKLLGIIHGLTNKVIKNKK-ETYLENKAKGIIPPTLEEFTHHSGEILANN-AKTL 247 F T + K+ K K YL N G + T++ + N+ + L Sbjct: 231 FMAMPTLV---------KIFKIKLIPEYLANFFMGSVRETMDY--REQNNVKRNDFMQLL 279 Query: 248 SDTVFKGYRDDLD-FNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEG 306 KG DD+D ++ D G + + +L +E +++ K S E + G Sbjct: 280 IQLKNKGKLDDVDEIKEKTDDGNEIK----ELEVEENRSD-QKFSFEEAAAQAFIFFVAG 334 Query: 307 HDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLR 366 +T++ L L + ++Q +V +E+ + G + T+ M YL VI E+LR Sbjct: 335 FETSSTTMVLALYELALQPEIQEKVRNEIKTVLGKHNGKITYEAAFGMDYLGNVIDETLR 394 Query: 367 LYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPEN 426 YP VI R+ N+D I + VIP GT+ I + LH KY+ +PE F+PD F E Sbjct: 395 KYPVAGVIIRQCNKDYKIPDSDMVIPKGTSTHIPIYSLHYDSKYFPNPEKFDPDRFTEEV 454 Query: 427 TQNRHYYSYIPFSAGPRSCVGRKY 450 R Y+Y+PF GPR C+G ++ Sbjct: 455 KSQRPRYAYLPFGEGPRHCIGMRF 478 >UniRef50_Q9PVE8 Cluster: Cytochrome P450 3A30; n=4; Percomorpha|Rep: Cytochrome P450 3A30 - Fundulus heteroclitus (Killifish) (Mummichog) Length = 496 Score = 124 bits (299), Expect = 6e-27 Identities = 75/238 (31%), Positives = 124/238 (52%), Gaps = 14/238 (5%) Query: 269 EKKRLAFLDLMIESSQNG----TNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324 +K R+ FL LMI+S +N ++DHEI + +F G++T+++ +F+ L + Sbjct: 264 QKSRVDFLQLMIDSQKNSGAQQDKSLTDHEILSQSMIFIFAGYETSSSSLTFLAYNLATN 323 Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR--DV 382 +V ++ +E+ F + P + +EM+YL+ VI ESLRL+P IA +L R Sbjct: 324 PEVMKKLQEEIDATFPNK-APVHYQPLMEMEYLDCVINESLRLFP----IAARLERVAKA 378 Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442 + VIP V+I T+ LHR P+ + +PE F P+ F +N N Y Y+PF +GP Sbjct: 379 AVEINGVVIPKDMVVMIPTWPLHRDPEIWPEPEAFKPERFSKKNKDNIDPYIYMPFGSGP 438 Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDI--ILKRAEGFQMKVEPR 498 R+C+G ++A + + + S E E + DI +L Q+K+ PR Sbjct: 439 RNCIGMRFALVLIKLAVVEILQQY-SFSVCKETEVPFEMDIQGLLAPKRPIQLKLVPR 495 Score = 42.3 bits (95), Expect = 0.029 Identities = 27/144 (18%), Positives = 64/144 (44%), Gaps = 5/144 (3%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHV--HIDKATEYRFFKPWLGEGLLISSGPKW 84 +G V ++ G + ++ + D + I+ +L +R P L + + I+ +W Sbjct: 67 YGKVWGIYDGRQPVLCVTDPEIIKAVLVKECLSFFTNRRNFRLNGP-LYDAVSIAEDDQW 125 Query: 85 RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLE 142 + R +++P+F LK I +S N++ +K + K D+ ++ ++D++ Sbjct: 126 KRIRSVLSPSFTSGRLKEMFEIMKNHSANLIRSMKKKADKDEPLDLKEFFGSYSMDVVTS 185 Query: 143 TAMGISRKTQDESGFDYAMAVMKM 166 TA + + + + + KM Sbjct: 186 TAFSVDIDSLNNPSDPFVTNIKKM 209 >UniRef50_Q9VGB3 Cluster: Probable cytochrome P450 313a3; n=2; Drosophila melanogaster|Rep: Probable cytochrome P450 313a3 - Drosophila melanogaster (Fruit fly) Length = 492 Score = 124 bits (298), Expect = 7e-27 Identities = 73/212 (34%), Positives = 112/212 (52%), Gaps = 5/212 (2%) Query: 280 IESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIF 339 IE +NG ++S E++ E + + +TT L LL + + Q VY EL ++F Sbjct: 274 IELHRNG--EMSREEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELF 331 Query: 340 GDS-DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVV 398 + D T+ D M +LERV+ E+LRL P VP R+ RD +S+ VIP G + Sbjct: 332 PVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPRETIRDFRLSS-GVVIPKGVGIG 390 Query: 399 IGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXX 457 I F HR ++ DP FNPD+FLP+N ++RH Y+YIPFS G R+C+G KY Sbjct: 391 IDIFATHRNRDHWGTDPSSFNPDHFLPDNVRDRHPYAYIPFSKGRRNCIGWKYGLMSSKL 450 Query: 458 XXXXXXRNFRTISEIPEKEFKLQGDIILKRAE 489 RN + + ++ + +I ++ A+ Sbjct: 451 ALSKILRNCKVSTSFRYEDLEFVDNIGMELAQ 482 Score = 52.4 bits (120), Expect = 3e-05 Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 2/139 (1%) Query: 14 QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY-RFFKPWL 72 ++ +++ Y +G+ VW+G V D E I S +++++ + + Sbjct: 52 KRKMSIRTKYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCT 111 Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDY 131 G+GLL KW RK + P F N+L SF+ IFN + +V L S VG+ V D Sbjct: 112 GDGLLSLEASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEKKVRDD 171 Query: 132 MSGTTVDILLETAMGISRK 150 + + I +T +G K Sbjct: 172 IVRWSFRIATQTTVGTDVK 190 >UniRef50_Q3E385 Cluster: Cytochrome P450; n=3; Chloroflexus|Rep: Cytochrome P450 - Chloroflexus aurantiacus J-10-fl Length = 452 Score = 123 bits (297), Expect = 1e-26 Identities = 67/199 (33%), Positives = 110/199 (55%), Gaps = 6/199 (3%) Query: 276 LDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 L++++ + T + +S +I++EV TI GH+TTA S++L LL H + + ++ E Sbjct: 231 LEMLVTARDADTGEQMSPKQIRDEVMTIFLAGHETTAGTLSWILHLLAHHGESERKLRAE 290 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + G R T AD ++ Y VI E+LRLYPP +++R L T+ +Y +PAG Sbjct: 291 YATVLGG--RNPTPADLPQLPYNRMVIDETLRLYPPTWILSRVLVEADTLG--DYELPAG 346 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454 V + ++ HR P ++ + E F+P+ F P + RH ++YIPF GPR C+G +A Sbjct: 347 AVVALSPYVTHRHPDFWPNAESFDPERFRPTAIEQRHKFAYIPFITGPRQCIGNNFALME 406 Query: 455 XXXXXXXXXRNFRTISEIP 473 ++FR +S IP Sbjct: 407 MQLILPMILQHFR-VSAIP 424 Score = 41.9 bits (94), Expect = 0.038 Identities = 27/124 (21%), Positives = 55/124 (44%), Gaps = 3/124 (2%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86 +G+++R+ LG + + D I+ I + + Y LG+GL+ S+G W Sbjct: 38 YGDLVRLSLGRHTMYLAIHPDMIKRITQENWK-NYIKRYPAMDEILGQGLVTSNGAHWLR 96 Query: 87 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETA 144 R+++ P FH + I + + ++ + + + + D+ M T I++ T Sbjct: 97 QRRLMQPAFHHQRIARMASIMVEEAEQMLARWETYARTRQPVDIQHEMMLLTQKIIVRTM 156 Query: 145 MGIS 148 G S Sbjct: 157 FGTS 160 >UniRef50_Q17PE0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 462 Score = 123 bits (297), Expect = 1e-26 Identities = 73/239 (30%), Positives = 124/239 (51%), Gaps = 5/239 (2%) Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 DE+ G K FLD ++ +++ G D EI+ V T++ G+DT+ ++ LLG Sbjct: 224 DEDQDGYHKPQIFLDQILSANRAG-KPFDDEEIQHNVRTMIAAGNDTSGQLMAYACLLLG 282 Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLE-MKYLERVILESLRLYPPVPVIARKLNRD 381 ++ +Q +VY E+ ++ + + + + L+ + Y E + E LRL P P IAR LN Sbjct: 283 MYPHIQEKVYSEIIELIPLTRKESISVEQLKTLTYTEMFMFECLRLCPIAPNIAR-LNM- 340 Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSA 440 I + IPAG I + LHR+ + D E F+P+ F PE + RH Y+++PFS Sbjct: 341 TPIELEGITIPAGHIFFISFYSLHRRKDIWGPDAEQFDPERFSPERSVGRHLYAFLPFSG 400 Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 G R+C+G +YA R +R +++ + K + D++L +K+E R+ Sbjct: 401 GSRNCIGWRYAMMSMKLMLVYLLREYRFRTDLKLSDLKFKFDMMLVLVFEHWVKIEKRR 459 Score = 65.3 bits (152), Expect = 4e-09 Identities = 44/169 (26%), Positives = 82/169 (48%), Gaps = 5/169 (2%) Query: 59 IDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL 118 ++K Y FFK L GL + W+ RK + TF++ IL SF+ IF + S +V +L Sbjct: 58 LEKPFLYDFFK--LDYGLFSAHYGLWKQQRKALNSTFNLKILHSFIPIFEECSRKLVNRL 115 Query: 119 KSEVG--KTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYK 176 ++ VG K ++ ++S T++++ T +G+ Q ESG + + ++ DI+ +R Sbjct: 116 QNHVGCSKPINLAQFVSQCTLEMVCGTTLGMEH-LQQESGSRFLHHIERVMDIMGERILS 174 Query: 177 FWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGII 225 M+ ++ T F Q+ L + ++I + N+ I Sbjct: 175 IPMQITALYFFTPMFWQEMHSLKMNRQYAAEIIDEGRRKMKANEQSNTI 223 >UniRef50_A7RNE6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 498 Score = 123 bits (297), Expect = 1e-26 Identities = 64/205 (31%), Positives = 107/205 (52%), Gaps = 3/205 (1%) Query: 294 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLE 353 E+ ++ T G +TTA SF L +G+H D+ +V +E+ ++ G + D Sbjct: 297 ELLDDFVTFFIAGQETTANQLSFALLEIGLHPDITHKVVEEVDKVIGSHVDFVEYDDLAN 356 Query: 354 MKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKD 413 + Y+ +V+ E+LR YPP + R ++T++ +VIPAGT + + + H P +KD Sbjct: 357 LSYMTQVLKETLRKYPPAAGVIRHSPEEITLN--GHVIPAGTGIGLNIYGAHHNPTNWKD 414 Query: 414 PEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIP 473 PEVF+P+ F EN N ++++PFS GPRSC+G+ +A + FR I P Sbjct: 415 PEVFDPERFNAENAPNIKPFTFLPFSLGPRSCIGQHFAQFEAKVLLARFLQKFR-IKLCP 473 Query: 474 EKEFKLQGDIILKRAEGFQMKVEPR 498 + L+ L+ +G +E R Sbjct: 474 GQTTALRQTGTLQPRDGVMCLIEKR 498 >UniRef50_UPI0000D555E9 Cluster: PREDICTED: similar to Cytochrome P450 6a2 (CYPVIA2) (P450-B1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 6a2 (CYPVIA2) (P450-B1) - Tribolium castaneum Length = 514 Score = 123 bits (296), Expect = 1e-26 Identities = 67/214 (31%), Positives = 107/214 (50%), Gaps = 3/214 (1%) Query: 286 GTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRP 345 GT+ D E + G +TT+ SF L + ++ ++ + E+ ++ G Sbjct: 300 GTSLTLD-EAAAQAFIFFLAGFETTSTTISFALFEMARNESIRTKARTEINKVLGKHGGK 358 Query: 346 ATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLH 405 T+ T+EM+YL+ VI E+LR YPP PV RK + + + +I G +V+I + LH Sbjct: 359 LTYEATMEMEYLDTVISETLRKYPPAPVFLRKCTKTYRVPDTDVIIEEGLSVLIPAYGLH 418 Query: 406 RQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRN 465 R P+Y+ DPE F+PD F +N Y+YIPF GPR C+G ++A ++ Sbjct: 419 RDPEYFPDPETFDPDRFNEDNRSKIWDYTYIPFGDGPRICIGMRFAMIQIKIALALILKS 478 Query: 466 FR-TISEIPEKEFKLQGD-IILKRAEGFQMKVEP 497 F +SE K++ IIL G + + P Sbjct: 479 FEFPLSEKTILPMKMENSGIILAPIGGIWLNLIP 512 >UniRef50_Q5KR92 Cluster: Cytochrome P450; n=1; Hodotermopsis sjoestedti|Rep: Cytochrome P450 - Hodotermopsis sjoestedti Length = 528 Score = 123 bits (296), Expect = 1e-26 Identities = 98/432 (22%), Positives = 190/432 (43%), Gaps = 35/432 (8%) Query: 74 EGLLIS-SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG--KTFDVHD 130 +G L S SG KWR+ R + P F LK+ G + ++ L+ +T ++ D Sbjct: 122 DGHLFSLSGAKWRNLRVKMTPIFTSGKLKTMFGTVVECGKDLQVALQKAANNEETVEIKD 181 Query: 131 YMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSF 190 +++ + D++ A GI C+ + + + +F +F+ Sbjct: 182 FLARYSTDVISSCAFGI------------------QCNCLKKPNAEFRNWGRRIFE--PH 221 Query: 191 FKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDT 250 F+Q +L I++ L ++ K + + + + + + E NN+ +D Sbjct: 222 FRQ--RLTSILNMLYPSLVYTLKLSLIPKD----VGNYFRKMVNETVEYRENNSVKKND- 274 Query: 251 VFKGYRDDLDFNDENDVGEKKRLAFLDLMIES-SQNGTNKISDHEIKEEVDTIMFEGHDT 309 F L N E+ + F++ E N + ++ + I + G +T Sbjct: 275 -FMQMMIQLK-NKTLGTAEENDMNFVEKETEELKSNASFDVTMNVIAAQAFVFYVAGFET 332 Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYP 369 ++ +F L L ++ D+Q R++ E+ + T+ EM+YL++V+ E+LR YP Sbjct: 333 SSTTMTFCLYELALNPDIQERLHAEIDTMLEKHGGNITYESIFEMEYLDKVVNETLRKYP 392 Query: 370 PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQN 429 PV ++ R+ + + + + + G V++ LH PKYY DPE F+P+ F E + Sbjct: 393 PVVILTRECTKPIKLRRTDVTLEKGLQVLLPVLGLHHDPKYYPDPERFDPERFSEEEKKK 452 Query: 430 RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF--RTISEIPEKEFKLQGDIILKR 487 R ++S++PF GPR C+G ++A N+ R + P + ++L Sbjct: 453 RPHFSFLPFGEGPRMCIGMRFALMQTKVGLISLLSNYEVRVSEKTPVPLVFEKSALVLTA 512 Query: 488 AEGFQMKVEPRK 499 A G + +E R+ Sbjct: 513 AGGMWLMIENRQ 524 >UniRef50_UPI00015B480C Cluster: PREDICTED: similar to cytochrome P450 monooxygenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 monooxygenase - Nasonia vitripennis Length = 730 Score = 122 bits (295), Expect = 2e-26 Identities = 60/217 (27%), Positives = 115/217 (52%), Gaps = 9/217 (4%) Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKE-----EVDTIMFEGHDTT 310 R+ +++ +N+V ++ +D++++ +N + +D EI E + G DTT Sbjct: 485 RETMEYRKKNNV---RKHDIVDVLMDIKEN-PEQFNDEEITELFLTAQAFVFFIAGFDTT 540 Query: 311 AAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPP 370 + S + L ++ D+Q ++ E+ + +++ ++ MKYL++V E+LR YPP Sbjct: 541 SNAMSHAMYELALNPDIQEKLRQEVNATYSENNGKFSYDSVRNMKYLDKVFKETLRKYPP 600 Query: 371 VPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNR 430 ++RK + + S IP GT+++I T+ +H P YY DP+ F+P+ F N NR Sbjct: 601 AFTLSRKSMNNHSFSGTKITIPKGTSLMIPTYAIHHDPSYYPDPDKFDPERFDEGNANNR 660 Query: 431 HYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467 + +++PF GPR+C+G ++A R F+ Sbjct: 661 IHMTFLPFGDGPRNCIGERFANNQFKVGIAMTVRKFK 697 >UniRef50_UPI0000D5558E Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=2; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 495 Score = 122 bits (295), Expect = 2e-26 Identities = 63/225 (28%), Positives = 110/225 (48%), Gaps = 3/225 (1%) Query: 274 AFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYD 333 + L+ + E + ++ + + + T M DT ++ +F +LG + +Q V Sbjct: 272 SMLESIAEMVMENPDCLTMQDCTDHLMTFMATSQDTQSSAVAFTCMMLGAYPHIQDLVVQ 331 Query: 334 ELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPA 393 EL ++ G D ++KYLE + ES+RL+P P I R D VIP Sbjct: 332 ELREVMGKKTS-LDLTDVSQLKYLEMCLKESMRLFPVGPFIFRDTTEDFQFD--KMVIPE 388 Query: 394 GTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXX 453 G TV++ + HR P++++ P+ F P++F PE RH ++IPFSAGPR C+ + Y+ Sbjct: 389 GVTVILSIYHAHRSPEHWEKPDEFYPEHFAPEAMSKRHPCAFIPFSAGPRRCIAQHYSYT 448 Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 N+ ++ KL DI ++ +G+ +K++ R Sbjct: 449 YMKILLATIVLNYEIECRFKAEDVKLIADISIRPQQGYLIKLKDR 493 Score = 118 bits (284), Expect = 4e-25 Identities = 61/209 (29%), Positives = 114/209 (54%), Gaps = 8/209 (3%) Query: 14 QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLG 73 +++ N + + + +R+W+G KL++F+ D + +++IL S K+ YRF +P+LG Sbjct: 51 EEIFNNFMAATAPYPSPVRLWVGPKLVLFVKDPNQLQLILQSSKITTKSFLYRFLEPFLG 110 Query: 74 EGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL-KSEVGKTFDVHDYM 132 +GL SSGP+ + HRK++ P F +++ + +F ++S VE L K+ G F++ ++ Sbjct: 111 KGLFTSSGPRQKHHRKLLQPLFSQRMIEGYCHLFQKHSKKFVEDLRKNANGPEFNISTFL 170 Query: 133 SGTTVDILLETAMGISRKTQDESGFDY---AMAVMKMCDIIHQRHYKFWMRSEIVFKLTS 189 T E M + + QD DY V K +I+ R FW+ +I FKL+S Sbjct: 171 QFTA----FEATMDLLLEDQDTHSIDYNEIPNYVRKFYEIVFTRVKSFWLHLDIFFKLSS 226 Query: 190 FFKQQTKLLGIIHGLTNKVIKNKKETYLE 218 ++++QTKL + + N++ + +E Sbjct: 227 YYREQTKLQSLATTVINEITETNVPKIIE 255 >UniRef50_Q964R0 Cluster: Cytochrome P450 6k1; n=1; Blattella germanica|Rep: Cytochrome P450 6k1 - Blattella germanica (German cockroach) Length = 524 Score = 122 bits (295), Expect = 2e-26 Identities = 72/227 (31%), Positives = 115/227 (50%), Gaps = 24/227 (10%) Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTI-- 302 K ++ + K + D ++F + N + R F+DL+I+ GT D E+ E+VD I Sbjct: 246 KETTEFLRKVFWDTINFRESNKIS---RDDFMDLLIQLKNKGTIDNEDGEVTEKVDKIDK 302 Query: 303 ---MFE----------------GHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD 343 +FE G +T A SF L L + D+Q R+ E+ + S+ Sbjct: 303 DSHLFEFTGDNLVSQPALFFTAGFETNATTLSFTLYELSLQPDLQNRLRSEIAGVMKTSN 362 Query: 344 RPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFM 403 T+ D M YL V+ E+LR YPP+P++ R +D + + +I T V I Sbjct: 363 GKPTYEDVFGMPYLHMVVSETLRKYPPLPLLDRVCLQDYKVPGTDLIIERDTPVFIALLG 422 Query: 404 LHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKY 450 LHR P+YY +PE ++P+ F EN + R Y+Y+PF GP +C+G ++ Sbjct: 423 LHRDPQYYPNPERYDPERFSEENKRQRKAYTYLPFGEGPHNCIGLRF 469 >UniRef50_UPI0000DB7C31 Cluster: PREDICTED: similar to Probable cytochrome P450 6a14 (CYPVIA14); n=1; Apis mellifera|Rep: PREDICTED: similar to Probable cytochrome P450 6a14 (CYPVIA14) - Apis mellifera Length = 490 Score = 122 bits (294), Expect = 2e-26 Identities = 69/213 (32%), Positives = 107/213 (50%), Gaps = 5/213 (2%) Query: 288 NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPAT 347 NK++ E + G +T++ +F L L +QD+Q +V +E+ Q + T Sbjct: 279 NKLTMMEAAAQAYVFFLAGFETSSTTVTFCLYELAKNQDIQNKVREEI-QTMIKKNGDLT 337 Query: 348 FADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ 407 + +M YL +VI E+LR YPPV ++ R DV +ST ++ IP GT + I F LHR Sbjct: 338 YNALNDMNYLHKVISETLRKYPPVVILNRICTNDVKLSTTDFCIPKGTCIAIPVFGLHRD 397 Query: 408 PKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA--XXXXXXXXXXXXRN 465 + +PE F+P+ F EN + RH Y Y+PF GPR C+G ++ Sbjct: 398 SNIFPNPEKFDPERFSEENIKTRHPYVYLPFGEGPRICIGLRFGLIQTKIAIINALLKNK 457 Query: 466 FRTISEIPEK-EFKLQGDIILKRAEGFQMKVEP 497 F+ P EF+ +G +IL G + +EP Sbjct: 458 FKFGPNTPSTLEFE-KGSLILIGKGGIHLNIEP 489 Score = 50.0 bits (114), Expect = 1e-04 Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 2/70 (2%) Query: 81 GPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVD 138 G KWR+ R + PTF +K F I N+ N + + L+ E G T DV D + + D Sbjct: 108 GKKWRNLRVKLTPTFTSGKIKQFFPILNEAGNILAKYLEEEARKGSTIDVKDIFARYSTD 167 Query: 139 ILLETAMGIS 148 I++ A GIS Sbjct: 168 IIMSVAFGIS 177 >UniRef50_Q629N7 Cluster: Cytochrome P450-related protein; n=24; Burkholderia|Rep: Cytochrome P450-related protein - Burkholderia mallei (Pseudomonas mallei) Length = 1373 Score = 122 bits (294), Expect = 2e-26 Identities = 69/218 (31%), Positives = 115/218 (52%), Gaps = 6/218 (2%) Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349 ++ E+ +EV T+ GH+TT AG ++ L L H V ++ DEL G R T Sbjct: 245 MTQQEVHDEVMTVFLAGHETTGAGLAWALYALAQHPAVLRQLRDELDARLGG--RAPTVQ 302 Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409 D ++ YL +V+ E LR+YPP+ R L D I Y IPA ++V + ++ HR P Sbjct: 303 DFEQLPYLSQVVDEVLRVYPPIWGFTRDLVEDDEIG--GYRIPARSSVFMSPYVTHRHPA 360 Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTI 469 ++++P+ F+P+NF + RH + Y PF G R C+G + A ++F + Sbjct: 361 FWRNPDAFDPENF-ASDAPARHRFVYFPFGGGMRKCIGFQTALLQMRVLVAVVAQHF-DL 418 Query: 470 SEIPEKEFKLQGDIILKRAEGFQMKVEPRKRVPTNVAR 507 + +P +L I L+ G ++ V+PR+R +++AR Sbjct: 419 NALPGHPIELGATISLRPVHGIRLIVKPRERQQSHLAR 456 Score = 51.6 bits (118), Expect = 5e-05 Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 1/81 (1%) Query: 17 VNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILN-SHVHIDKATEYRFFKPWLGEG 75 + + L Q +G+V R LG + L D I+ +L +H + + Y FK + G+G Sbjct: 27 ITMLLRLHQQYGDVARNRLGPFVTHALAHPDHIQYVLQENHRNYVRGRFYDNFKMFFGDG 86 Query: 76 LLISSGPKWRSHRKMIAPTFH 96 LL + G WR HR+++ P FH Sbjct: 87 LLTTDGEFWRRHRRVVQPLFH 107 >UniRef50_Q27691 Cluster: Cytochrome P450; n=2; Musca domestica|Rep: Cytochrome P450 - Musca domestica (House fly) Length = 503 Score = 122 bits (294), Expect = 2e-26 Identities = 65/223 (29%), Positives = 114/223 (51%), Gaps = 8/223 (3%) Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIE-SSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGS 314 R +++ + N V K F+DL++E ++ G +S ++ G +T++ Sbjct: 257 RQTVEYRERNQV---KCNDFMDLLMEIRAKEGEEGLSFEQMAALTFDFFLAGFETSSTTM 313 Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374 +F L L + ++Q ++ E+ I DS+ ++ +M +LE+ I E+LRLYP + + Sbjct: 314 AFTLYELARNPEIQEKLRTEILDILKDSNDELSYEALQKMSFLEQSISETLRLYPVLATL 373 Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434 R NRD + ++I VVI +H P+YY++PE FNP+ F E + RH + Sbjct: 374 VRVANRDYPVPDSQHIIEKDIQVVIPVHAIHHDPEYYENPEEFNPNRFAAEECERRHSST 433 Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR----TISEIP 473 Y+PF GPRSC+G ++ R++R ++EIP Sbjct: 434 YLPFGDGPRSCIGMRFGKMQTKIGLVSLLRHYRFECCPLTEIP 476 >UniRef50_A7SRX7 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 472 Score = 122 bits (294), Expect = 2e-26 Identities = 62/184 (33%), Positives = 105/184 (57%), Gaps = 4/184 (2%) Query: 270 KKRLAFLDLMIESS--QNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327 K+ LDLM+ ++ +N + K+SD E+ + + G++TT SFV L + DV Sbjct: 274 KEAKDMLDLMLSAAANENTSKKLSDMEVLAQSLIFLIAGYETTNITLSFVAYSLATNPDV 333 Query: 328 QARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387 Q ++ E+ ++ + D+ ++ + YL+ VI E+LRLYPP V +R+ +D I K Sbjct: 334 QEKLQREIDSVWTEEDQMPSYDTVHNLPYLDMVISETLRLYPPGFVASRECTQDCVI--K 391 Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447 Y G ++ I + +H P+++ DPE F+P+ F E Q+R YSY+PF GP +C+G Sbjct: 392 GYRFRKGLSIFIDAYSMHHDPEFWTDPERFDPERFSRECKQSRDPYSYLPFGHGPHNCIG 451 Query: 448 RKYA 451 ++A Sbjct: 452 MRFA 455 Score = 48.8 bits (111), Expect = 3e-04 Identities = 36/133 (27%), Positives = 66/133 (49%), Gaps = 7/133 (5%) Query: 23 YAQTFGNVIRVWL-GSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSG 81 Y + +G + ++L G K V + D D I+ N V + + R +P+ + + Sbjct: 77 YYKKYGRLYAMFLVGKKPSVIVGDPD---IVKNIMVKEFSSFQDRPVEPF-NSFMTRAKY 132 Query: 82 PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDI 139 KW R ++P F + +K V + N + + ++ KL ++ G +F VH + G T+D Sbjct: 133 DKWHRIRTSLSPAFSAHKMKLMVPLINSSCDVLINKLTKIADSGTSFFVHKFHQGLTMDT 192 Query: 140 LLETAMGISRKTQ 152 +L+TA GI + Q Sbjct: 193 ILKTAFGIHSEAQ 205 >UniRef50_Q5TXA2 Cluster: ENSANGP00000026709; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000026709 - Anopheles gambiae str. PEST Length = 198 Score = 122 bits (293), Expect = 3e-26 Identities = 61/181 (33%), Positives = 107/181 (59%), Gaps = 6/181 (3%) Query: 273 LAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVY 332 + FLD ++ + Q G + EI+ + TI+ G +TTA +F+L ++ +H +VQ RV+ Sbjct: 1 MVFLDQLLHT-QRGGRDLEMQEIENHLYTIIGAGSETTANQVAFILLMIAMHPEVQDRVH 59 Query: 333 DELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIP 392 +E+ I+G + ++ YLE+VI E++R+YP P+I R+ T+ + ++P Sbjct: 60 EEIVSIYGRAAPDFSYETISAQTYLEQVIKETMRVYPVAPLIGRETIE--TVKLGDVIVP 117 Query: 393 AGTTVVIGTFMLHRQPKYYKD-PEVFNPDNFLPE--NTQNRHYYSYIPFSAGPRSCVGRK 449 +G T++I LHR + + + VF+PD F P + + +H +SYIPF GPR+C+G + Sbjct: 118 SGVTLLINILTLHRNKELWGERAHVFDPDRFDPALYDAKKQHPFSYIPFGGGPRNCIGYR 177 Query: 450 Y 450 Y Sbjct: 178 Y 178 >UniRef50_A7SCY4 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 505 Score = 122 bits (293), Expect = 3e-26 Identities = 57/185 (30%), Positives = 99/185 (53%), Gaps = 3/185 (1%) Query: 285 NGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDR 344 +G I+D E+ + T+ G +TTA +F + +G H ++ R+ DE+ ++ G R Sbjct: 290 DGDKPIADEEMIDNFLTLFIAGQETTANQLAFTVYEIGKHPQIEMRIQDEVERVLGGKSR 349 Query: 345 PATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFML 404 + D +KY+ + + ESLRL+PP+ ++R +D+T++ + +IP T V++ F+ Sbjct: 350 -VDYEDLNLLKYVNQTLKESLRLHPPISGLSRMTTKDITLN--DVIIPKDTCVILSQFVT 406 Query: 405 HRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXR 464 HR P+ + DP+ F+P+ F EN Y PFS GPRSC+G A + Sbjct: 407 HRDPEVWNDPDTFDPERFALENVGRISSSMYFPFSLGPRSCIGNYLAQFEAKVIMARLYQ 466 Query: 465 NFRTI 469 F+ + Sbjct: 467 QFKVV 471 Score = 40.7 bits (91), Expect = 0.089 Identities = 25/117 (21%), Positives = 55/117 (47%), Gaps = 3/117 (2%) Query: 49 IEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK-WRSHRKMIAPTFHINILKSFVGIF 107 +E+ L + ++ ++ F + +G+L P+ W+ R M++P FH K +G+F Sbjct: 103 LELDLPKAEQVYQSLKFVFGQRAARDGILTECDPEIWKRKRGMLSPAFHRLWFKDSMGMF 162 Query: 108 NQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMA 162 N + + KL+ + G+ D+ + S T+D++ + + D ++ A Sbjct: 163 NAVCDKFLVKLEGYASSGEAVDLSEMFSRVTMDVIGKVGFNNDLRATDNDKCEFRAA 219 >UniRef50_Q70AR5 Cluster: Putative cytochrome P450; n=1; Streptomyces peucetius|Rep: Putative cytochrome P450 - Streptomyces peucetius Length = 477 Score = 121 bits (292), Expect = 4e-26 Identities = 65/212 (30%), Positives = 109/212 (51%), Gaps = 5/212 (2%) Query: 291 SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFAD 350 +D +I++EV GH+T + S+ LL ++ + + R+ E+ ++ + R T D Sbjct: 271 TDEQIRDEVSGFFVAGHETVSTALSWTWYLLSLNPESRRRLQAEVDEVL--AGRVPTVDD 328 Query: 351 TLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKY 410 ++ Y V+ ES+RLYPP+ V R D I Y IP G VV+ ++ HR P++ Sbjct: 329 LPKLTYTTMVLQESMRLYPPIFVYMRCAAEDDVIG--GYHIPEGRWVVVCPYVTHRHPEF 386 Query: 411 YKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTIS 470 + +PE F P+ F PEN+ NRH +Y+PF AGPR C+G +A + FR + Sbjct: 387 WDNPEGFEPERFTPENSANRHRMAYLPFGAGPRKCIGDSFAMLQMPLVVAMIAQRFR-LD 445 Query: 471 EIPEKEFKLQGDIILKRAEGFQMKVEPRKRVP 502 + ++ + I L+ + M + P + P Sbjct: 446 LVEGQQVFPEPAISLRPRDPLMMWLRPNEETP 477 Score = 35.9 bits (79), Expect = 2.5 Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 2/63 (3%) Query: 72 LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVE--KLKSEVGKTFDVH 129 +G+GL+ + G W R++ P FH +IL+ F F ++ +++ + ++ G+ D+ Sbjct: 109 VGDGLVAAEGTSWLRSRRLTQPAFHRDILRRFGDSFTASTAELLDGWERRARDGEPLDIK 168 Query: 130 DYM 132 M Sbjct: 169 SEM 171 >UniRef50_Q1D9Z9 Cluster: Cytochrome P450 family protein; n=1; Myxococcus xanthus DK 1622|Rep: Cytochrome P450 family protein - Myxococcus xanthus (strain DK 1622) Length = 458 Score = 121 bits (292), Expect = 4e-26 Identities = 61/177 (34%), Positives = 103/177 (58%), Gaps = 5/177 (2%) Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 L +M+E+ + T ++SD ++++EV T++ GH+TTA+ ++ + LL H V+ + E Sbjct: 240 LQMMMEAHDDDTGERMSDSQLRDEVLTLLLAGHETTASALAWTIMLLSQHPGVRRDMESE 299 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 L + G R T D ++ RV+ ESLRLYPP ++R ++ + + IP G Sbjct: 300 LARELGG--RNPTHEDLPRLELTHRVVDESLRLYPPAWALSRIATKEDLVG--GFRIPKG 355 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 ++I ++ HR P + +PE F+PD FLPE Q R +++ PF GPR C+G ++A Sbjct: 356 AHLLIAPWVTHRHPSIWDNPEGFDPDRFLPEREQARPRFAWFPFGGGPRQCIGNQFA 412 Score = 52.8 bits (121), Expect = 2e-05 Identities = 33/136 (24%), Positives = 63/136 (46%), Gaps = 6/136 (4%) Query: 24 AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHV--HIDKATEYRFFKPWLGEGLLISSG 81 A+ +G+V+R+ +G +V + D + +L H + ++ +R + LG GLL S G Sbjct: 42 AREYGDVVRLPMGPADLVLVAHPDGVRHVLQDHARNYSKQSRGFRVLQELLGHGLLTSDG 101 Query: 82 PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDI 139 W R++ P FH + F + ++ + +++ G F+V + + T+ I Sbjct: 102 DHWLRQRRLAQPAFHRQRVAGFTRTMVDAAADLAATMEARADTGAAFNVAEDFTRLTLRI 161 Query: 140 LLETAMG--ISRKTQD 153 T G +S T D Sbjct: 162 ASSTLFGADVSSATHD 177 >UniRef50_Q25176 Cluster: Cytochrome P-450; n=24; Ditrysia|Rep: Cytochrome P-450 - Heliothis virescens (Noctuid moth) (Owlet moth) Length = 532 Score = 121 bits (292), Expect = 4e-26 Identities = 98/428 (22%), Positives = 192/428 (44%), Gaps = 43/428 (10%) Query: 40 IVFLVDADDIE-IILNSHVH-IDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHI 97 I+ ++D D ++ I + H +D+ + F P G GLL+ G +W++ R ++P F Sbjct: 79 ILVVLDVDTVKRITVKDFEHFVDRRSFTSSFDPIFGRGLLLLHGDEWKAMRSTMSPAFTS 138 Query: 98 NILKSFVGIFNQNSNNVVEKLKSEV---GKTF---DVHDYMSGTTVDILLETAMGISRKT 151 + ++ V + + ++ L+ ++ GK + + M+ D++ A G+ + Sbjct: 139 SKMRLMVPFMEEIALEMIRVLRGKIKDSGKPYIDVEAKSMMTRYANDVIASCAFGLKVNS 198 Query: 152 Q--DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVI 209 Q D + + A+ K +KF F FF+ L + L ++ Sbjct: 199 QASDHEFYVNSQAITK---------FKF-----SAFLKVLFFRC---LPSVAQKLKMSLV 241 Query: 210 KNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGE 269 + Y N ++ T+++ +++ N+ + V KG ++++D Sbjct: 242 PRECSDYFSN----VVLTTMKD--REKNKVVRNDLINILMEVKKGQLT----HEKDDADA 291 Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329 A ++ + + +D ++ + +F G DT + SF+L L ++ DVQ Sbjct: 292 DAGFATVEESHIGRKQHNYEWTDSDLIAQAALFLFAGFDTVSTSMSFLLYELAVNPDVQD 351 Query: 330 RVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI----- 384 R+ E+ + + + M YL+ V+ E LRL+PP V+ R +D I Sbjct: 352 RLLQEIREYDEKNHGKIDYNVVQSMTYLDMVVSEGLRLWPPAAVVDRVCVKDYNIGRPNK 411 Query: 385 -STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443 +TK+ +I G V I ++ HR PK++ +P F+P+ F PEN ++Y F GPR Sbjct: 412 KATKDLIIHTGQAVAISPWLFHRNPKFFPEPAKFDPERFSPENRHKILPFTYFSFCLGPR 471 Query: 444 SCVGRKYA 451 +C+G ++A Sbjct: 472 NCIGSRFA 479 >UniRef50_A7HP72 Cluster: Cytochrome P450; n=1; Parvibaculum lavamentivorans DS-1|Rep: Cytochrome P450 - Parvibaculum lavamentivorans DS-1 Length = 470 Score = 121 bits (291), Expect = 5e-26 Identities = 72/222 (32%), Positives = 112/222 (50%), Gaps = 5/222 (2%) Query: 278 LMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ 337 LM+ S+ G D ++++EV T + GH+TTA S+V LL +H + Q R+Y+E++ Sbjct: 251 LMVSQSKAGHEMTLD-QVRDEVATFLLAGHETTATTMSWVWYLLTVHPEWQERLYEEVWA 309 Query: 338 IFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTV 397 + R T D + VI E+LRLYPPV + R+ + T T + I G TV Sbjct: 310 V--TEGRRLTIDDVPALVETRAVIEEALRLYPPVANLMRRAIK-TTELTPDITIERGQTV 366 Query: 398 VIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXX 457 +I ++LHR ++++P+ F+P FL E R + YIPF GPR C+G +A Sbjct: 367 LISPWLLHRHRFFWREPDRFDPTRFLGEEAATRPRHLYIPFGGGPRICIGASFALLEAVL 426 Query: 458 XXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 + R + I + Q I+L+ Q V PR+ Sbjct: 427 ILATFMQRAR-VKVINADQVMPQARIVLRPNVALQAVVTPRR 467 Score = 48.8 bits (111), Expect = 3e-04 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 3/103 (2%) Query: 45 DADDIEIILNSHV-HIDKA-TEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKS 102 D D I IL S H K + KP LG GLL + G WR +RK+ AP F + ++ Sbjct: 74 DPDAIRRILVSDAEHFPKDDNQLAILKPLLGNGLLTAEGATWRRNRKLAAPIFQHSSVRD 133 Query: 103 FVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 145 F +F + + + + G F + M+ T++I+ ET + Sbjct: 134 FAPLFVRAAERSARRALEQQG-FFPLDREMTKLTLEIIGETVL 175 >UniRef50_UPI0000E48D2E Cluster: PREDICTED: similar to MGC64404 protein; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC64404 protein - Strongylocentrotus purpuratus Length = 509 Score = 120 bits (290), Expect = 7e-26 Identities = 60/174 (34%), Positives = 100/174 (57%), Gaps = 3/174 (1%) Query: 278 LMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ 337 L E KI ++ +E T G +TT+ +F L +G H+DV R+ DE+ + Sbjct: 292 LQAEDDVGNGEKIETADLIDEFGTFFVAGQETTSNLLAFTLLEIGRHKDVAKRLKDEVDE 351 Query: 338 IFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTV 397 + G S +D +++Y+ RV E++RL PPV +R+L DV + YVIP G +V Sbjct: 352 VLG-SKSIIEHSDLTKLEYMSRVFKETMRLNPPVSGASRELASDV--QSCGYVIPKGASV 408 Query: 398 VIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 + +++ R +Y+ DP +FNPD F+P + RH+++Y PF+ G R+C+G++ A Sbjct: 409 LFLSYLTSRLEEYFDDPLLFNPDRFIPTDETPRHFFAYFPFAIGQRNCIGQQLA 462 >UniRef50_Q1IM54 Cluster: Cytochrome P450; n=1; Acidobacteria bacterium Ellin345|Rep: Cytochrome P450 - Acidobacteria bacterium (strain Ellin345) Length = 460 Score = 120 bits (290), Expect = 7e-26 Identities = 66/223 (29%), Positives = 117/223 (52%), Gaps = 5/223 (2%) Query: 276 LDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDEL 335 L +MI++ + +++++V TI G++TTA S+ LLG + +V+ RV E+ Sbjct: 242 LSMMIQAIPDVETPEGKEQLRDQVVTIFLAGYETTANALSWTFRLLGENPEVERRVLAEV 301 Query: 336 YQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGT 395 + + R A+ D ++KY+E V+ ES+RLYPP + R+ D + +Y +P GT Sbjct: 302 DDVL--NGRMASVEDVPQLKYIEMVLAESMRLYPPAWAMVRQGINDFQLG--DYFLPGGT 357 Query: 396 TVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXX 455 TV++ +++HR +++ DP F+P+ F PE R ++Y PF G R C+G +A Sbjct: 358 TVMMSQWVMHRSEEFWLDPLRFDPERFRPEAKAGRPKFAYFPFGGGGRQCIGEAFAWMEG 417 Query: 456 XXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 + +R + + F+ Q I L+ G ++ E R Sbjct: 418 ALLLATLVQKYR-FRLVAGQTFEPQSLITLRPRNGVRVVAEAR 459 Score = 46.8 bits (106), Expect = 0.001 Identities = 28/105 (26%), Positives = 54/105 (51%), Gaps = 5/105 (4%) Query: 27 FGNVIRVWLGSKLIVFLVDADDI-EIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWR 85 +G V +G+K +VFL DA+ I E+++ + + K R K LG G++ + WR Sbjct: 50 YGKVGGYRVGNKRVVFLADAELIREVLVVQNDNFVKGEPVRRTKVLLGNGMITAEQQDWR 109 Query: 86 SHRKMIAPTFHINILKSF----VGIFNQNSNNVVEKLKSEVGKTF 126 S R+ P FH ++S+ VG+ + + + ++ ++ + F Sbjct: 110 SQRQAAQPAFHRQRIRSYADQMVGLTIETRDRIAPGIEFDLAQMF 154 >UniRef50_A5P357 Cluster: Cytochrome P450; n=1; Methylobacterium sp. 4-46|Rep: Cytochrome P450 - Methylobacterium sp. 4-46 Length = 463 Score = 120 bits (290), Expect = 7e-26 Identities = 70/232 (30%), Positives = 116/232 (50%), Gaps = 6/232 (2%) Query: 268 GEKKRLAFLDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326 G + R L L++ + + + + D ++ + + T + GH+TTA ++ L LL +H Sbjct: 235 GVEGRDDLLSLLVAARDPESGRAMDDRDVADNLLTFVTAGHETTALALAWTLYLLALHPA 294 Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386 ++ARV E+ + G + L + + I E++RLYPP PV+ R +V + Sbjct: 295 IEARVVAEVEAVTGGGPLAPHHVEALG--FTRQAIQEAMRLYPPAPVLVRAALEEVDVG- 351 Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446 + I GT V + + +HR + +P+ F+PD F PE + R Y+Y+PF AGPR C+ Sbjct: 352 -GHRIGPGTPVTVPIYAIHRHALLWDEPDRFDPDRFAPEAAKARDRYAYLPFGAGPRICI 410 Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 G +A R+ R + P L+ I L+ AEG M+V PR Sbjct: 411 GMSFALMEAVAILAVLIRDLR-FALRPGFVPTLKQRITLRPAEGMPMRVAPR 461 Score = 40.3 bits (90), Expect = 0.12 Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 3/108 (2%) Query: 41 VFLVDADDIEIILNSHVHIDKATEY--RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHIN 98 +F++D + +L + +E R P LG+ +L + G +WR R+ AP F Sbjct: 61 LFVMDPGLVRTVLVDRAESFEKSEVLRRSLSPALGDAILTADGARWRWQRRAAAPIFRNE 120 Query: 99 ILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTVDILLETAM 145 + F+ + E LK G D+ M TT DI+ T + Sbjct: 121 RILGFLPAMIAAAERTREALKGLPPGTEADLAQVMMRTTFDIIAATML 168 >UniRef50_Q964T2 Cluster: Cytochrome P450 9e2; n=2; Blattaria|Rep: Cytochrome P450 9e2 - Blattella germanica (German cockroach) Length = 533 Score = 120 bits (290), Expect = 7e-26 Identities = 59/164 (35%), Positives = 91/164 (55%), Gaps = 1/164 (0%) Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATF 348 K D ++ + F G DT + F+ LL + DVQ R+ DE+ Q ++D T+ Sbjct: 318 KWDDDDLTAQAVLFFFAGFDTASTLLCFMSHLLATNPDVQNRLQDEIDQSLEENDGKLTY 377 Query: 349 ADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK-NYVIPAGTTVVIGTFMLHRQ 407 MKYL+ V+ ESLRLYPP RK ++ + + +Y + G V I + +H Sbjct: 378 EAIHSMKYLDMVVSESLRLYPPAIFTDRKCVKNYRLPMEPSYTLEPGDAVWIPIYAIHHD 437 Query: 408 PKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 PKYY +PE F+P+ F EN N ++Y+PF +GPR+C+G ++A Sbjct: 438 PKYYPNPEKFDPERFSDENKDNIKPFTYLPFGSGPRNCIGNRFA 481 >UniRef50_UPI0000E4657A Cluster: PREDICTED: similar to cytochrome P450 3A27; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cytochrome P450 3A27 - Strongylocentrotus purpuratus Length = 460 Score = 120 bits (289), Expect = 9e-26 Identities = 108/438 (24%), Positives = 188/438 (42%), Gaps = 40/438 (9%) Query: 72 LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVH 129 L G+L + +WR R +++P+F LKS V + + + +V+ + E GKT + Sbjct: 48 LAGGMLAAKDERWRKLRSLLSPSFTSVKLKSMVPLMRECAEVLVDIFTKREEEGKTIECK 107 Query: 130 DYMSGTTVDILLETAMGI---SRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFK 186 + +D++ A G+ S+ QDE YA + + + M Sbjct: 108 ELYGPYAMDVIGSCAFGLRVNSQTNQDEPFIKYAKRIFNFN--VTNPAFLISMLFPWTAP 165 Query: 187 LTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKT 246 + +FFK LG V K+ ++ +L G+ + + +G+ Sbjct: 166 IFNFFK-----LG-------SVPKDIEQFFL-----GVFEKAIAD-RQANGD---TGKSD 204 Query: 247 LSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNK--ISDHEIKEEVDTIMF 304 + + +++D D N ND + DL E+S K ++ EI T + Sbjct: 205 FLELMMSAHKEDDDVNIMNDAEDD----IADLAQETSWKPKQKTALNRQEIIGNSITFLL 260 Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364 G++T++ FV LL +Q VQ + E+ ++ S TF +M+YL VI+E+ Sbjct: 261 AGYETSSTALGFVSYLLATNQHVQDLLVAEVKEM-APSQSDVTFETVTKMEYLNMVIMEA 319 Query: 365 LRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP 424 +R+YPP V+ R N+++T + N I G + I + L + DPE F+P+ F Sbjct: 320 MRIYPPGEVLERVCNKEITYN--NITIKKGQYIFIPIWNLQHDSDLWPDPETFDPERFSK 377 Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEF--KLQGD 482 + N H ++PF GP +C+G ++A + FR PE E KL Sbjct: 378 DRRGNNHPCGWLPFGIGPHTCIGVRFAMLEIKVAMVCILQKFR-FDTCPETEIPPKLGNL 436 Query: 483 IILKRAEGFQMKVEPRKR 500 L G +++ P R Sbjct: 437 SFLTPPNGITLRITPHSR 454 >UniRef50_O76345 Cluster: Cytochrome P450; n=1; Homarus americanus|Rep: Cytochrome P450 - Homarus americanus (American lobster) Length = 518 Score = 120 bits (289), Expect = 9e-26 Identities = 55/164 (33%), Positives = 96/164 (58%), Gaps = 4/164 (2%) Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATF 348 K++D E+ + + G +TT+ ++ LL ++ D+Q +++ E+ ++ G +R ++ Sbjct: 283 KLTDEEVVDNAFLFLLAGFETTSTALTYTSYLLALNPDIQEKIFQEVEEVVG-LERAPSY 341 Query: 349 ADTLEMKYLERVILESLRLYPPVP-VIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ 407 D ++ Y E V LES R+YPPV I R+ +D Y IPAGT V + + +H Sbjct: 342 EDLSKLVYTEAVALESTRMYPPVTGFITRQATQDWQYGP--YTIPAGTEVEVPVWSIHHN 399 Query: 408 PKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 P+ Y PE+F P+ FLP+ ++RH +Y+ F GPR+C+G ++A Sbjct: 400 PELYPQPELFKPERFLPKAKKDRHTMAYLGFGGGPRNCLGLRFA 443 >UniRef50_UPI00015B5073 Cluster: PREDICTED: similar to cytochrome P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 1350 Score = 120 bits (288), Expect = 1e-25 Identities = 62/174 (35%), Positives = 94/174 (54%), Gaps = 7/174 (4%) Query: 282 SSQNGTNKISDHE---IKEEVDTIMF---EGHDTTAAGSSFVLCLLGIHQDVQARVYDEL 335 S N KI+D + + E V MF G +TTA+ ++ L L +QD+Q +Y+E+ Sbjct: 225 SKSNSLTKITDADKITMVEAVGQSMFFFAAGQETTASAITYCLYELSFNQDIQEELYNEI 284 Query: 336 YQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGT 395 Q+ S T+ M YL+ V E+LR +P P++ R+ + D + ++VI GT Sbjct: 285 SQV-AHSPEGLTYEKLFSMPYLDMVFRETLRKHPGAPMLNRQASEDFVVPGSHFVIKKGT 343 Query: 396 TVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449 +VI LH P Y DP+ F+P F EN RH ++YIPF GPR C+G++ Sbjct: 344 RIVIPIKALHADPDIYPDPDKFDPTRFTSENKAKRHAFTYIPFGEGPRHCIGKR 397 Score = 39.5 bits (88), Expect = 0.20 Identities = 38/181 (20%), Positives = 83/181 (45%), Gaps = 11/181 (6%) Query: 41 VFLVDADDIEIILNSHVH--IDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHIN 98 +FL+D + I++IL H + ++ T Y K L GL+ KW+ R ++PTF Sbjct: 20 LFLMDPELIQLILVKHFNSFYNRGTLYNESKDPLSTGLVRLYDEKWKRLRVKLSPTFTSG 79 Query: 99 ILKSFVGIFNQNSNNVVEKLKSEVGKT--FDVHDYMSGTTVDILLETAMGISRKTQDESG 156 LK + + + ++ + + K+ ++ D + T+D + A G + + + Sbjct: 80 KLKLMYPLVKEICDELLRVYEDVLDKSDVVEIKDITNRFTIDCISSIAFGFNCDSLHQPD 139 Query: 157 FDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFF---KQQTKLLGIIHGLTNKVIKNKK 213 ++ +K I + F + S V +L S F +++ K+ + L K++ +++ Sbjct: 140 NEF----LKYGKISNDLGRVFLIFSFFVPRLVSLFPIPEKRKKVSEFFYDLFEKMVSHRR 195 Query: 214 E 214 + Sbjct: 196 K 196 >UniRef50_Q9VYQ7 Cluster: Probable cytochrome P450 311a1; n=2; Drosophila melanogaster|Rep: Probable cytochrome P450 311a1 - Drosophila melanogaster (Fruit fly) Length = 483 Score = 120 bits (288), Expect = 1e-25 Identities = 77/232 (33%), Positives = 114/232 (49%), Gaps = 10/232 (4%) Query: 266 DVGEKKRLA--FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323 D+GE A LD ++ + G + +S EI++E++T +F G DTT A SFVL L Sbjct: 253 DMGEPAGRAHNLLDTLLLAKFEGQS-LSRREIRDEINTFVFAGVDTTTAAMSFVLYALAK 311 Query: 324 HQDVQARVYDELYQIFGDSDRPATFADTLE-MKYLERVILESLRLYPPVPVIARKLNRDV 382 + Q R+ EL + D T D L + YLE +I E LRLY VP R+ + Sbjct: 312 FPETQTRLRKELQDVALDE---TTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQST 368 Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPEN-TQNRHYYSYIPFSAG 441 I + Y AG T+ I + L +YY DP F P+ +LPE+ +SYIPFS G Sbjct: 369 EIGGRTYC--AGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGG 426 Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQM 493 P C+GR+Y+ R F+ + +L+ ++LK +G + Sbjct: 427 PHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINV 478 Score = 80.6 bits (190), Expect = 9e-14 Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 1/192 (0%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86 FG R+ LG +L VFL A++ L+ + KA + +P +G GLLIS G W Sbjct: 63 FGATYRLRLGPQLWVFLHSAEETRQALHDPT-LRKADTFMQLEPLIGNGLLISHGAHWTR 121 Query: 87 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMG 146 R+++ P F +L+SF + +V +L + G +V + + +D +++T+MG Sbjct: 122 QRRLLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVTEPLFACLLDAIVDTSMG 181 Query: 147 ISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTN 206 TQ A ++ +R + S+ +F+ T ++ + L +IH Sbjct: 182 AQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQME 241 Query: 207 KVIKNKKETYLE 218 VI+ + + L+ Sbjct: 242 SVIEKRAKELLD 253 >UniRef50_UPI0000D576F7 Cluster: PREDICTED: similar to Cytochrome P450 6a8 (CYPVIA8); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 6a8 (CYPVIA8) - Tribolium castaneum Length = 491 Score = 119 bits (287), Expect = 2e-25 Identities = 66/226 (29%), Positives = 112/226 (49%), Gaps = 5/226 (2%) Query: 257 DDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISD-HEIKEEVDTIMFEGHDTTAAGSS 315 D + F +EN+ R F+ +I+ ++ E+ + G +T+ A S Sbjct: 250 DIIKFREENNY---TRDDFMQFLIKLKNKSAKQVFTLEEVASQCVLFFIAGFETSHATMS 306 Query: 316 FVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIA 375 F L L HQD+Q +V +E + + + T+ ++KYL++V+ E+LR YP V + Sbjct: 307 FALYELAKHQDIQQKVREEFWAVVDSQESEITYEAVQKLKYLDQVLNETLRKYPVVMYLT 366 Query: 376 RKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSY 435 R+ +D + VI GTTV+I T L+ YY +P+ F+P F EN + RH + Sbjct: 367 RRCIKDYKVPEDGAVIEKGTTVIIPTVALNYDENYYPNPKKFDPQRFSEENKKLRHPCIH 426 Query: 436 IPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQ 480 +PF GPR C+GR++A +N+ T++ + KL+ Sbjct: 427 LPFGLGPRFCIGRRFALIQVKVGLVLLLKNYSFTVNPNTREPIKLK 472 >UniRef50_Q825N1 Cluster: Cytochrome P450 hydroxylase; n=6; Actinomycetales|Rep: Cytochrome P450 hydroxylase - Streptomyces avermitilis Length = 504 Score = 119 bits (287), Expect = 2e-25 Identities = 71/229 (31%), Positives = 125/229 (54%), Gaps = 8/229 (3%) Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 LD M+++++ GT +++ I+ +V T + GH+TT+ SF L L H DV AR E Sbjct: 257 LDRMLDTARPGTGERLAPENIRRQVITFLVAGHETTSGALSFALHYLSRHPDVAARARAE 316 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + +++G + RP + +++Y+ RV+ ESLRL+P P AR+ RD T+ + + G Sbjct: 317 VDRVWGGTARPG-YDQVAKLRYVRRVLDESLRLWPTAPAFAREARRD-TVLGGVHPMREG 374 Query: 395 TTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXX 453 ++ T MLHR P + D E F+PD F + ++R +++ PF G R+C+GR++A Sbjct: 375 AWALVLTAMLHRDPGVWGADAERFDPDRFDAQAVRSRAAHTFKPFGTGARACIGRQFALH 434 Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRVP 502 R + +E P ++ + L EG +++++ +RVP Sbjct: 435 EATLVLGLLLRRYELRAE-PGYRLRVAERLTL-MPEGLRLRLD--RRVP 479 >UniRef50_A4X8D8 Cluster: Cytochrome P450; n=5; Actinomycetales|Rep: Cytochrome P450 - Salinispora tropica CNB-440 Length = 452 Score = 119 bits (287), Expect = 2e-25 Identities = 65/208 (31%), Positives = 109/208 (52%), Gaps = 5/208 (2%) Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349 ++ +++E+ T++ GH+TTA+ + L+ V+ R+ +E + G R +A Sbjct: 248 VARRRMRDELVTLLLAGHETTASTLGWTFHLINQDPRVRVRLREEAIDVLGG--RLPEYA 305 Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409 D + Y + V+ E++RLYPPV +++R L RD + Y +PA V+I + LHR P Sbjct: 306 DLARLTYTKMVVSEAMRLYPPVWMLSR-LARDADV-VDGYPVPARADVLICPYTLHRHPA 363 Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTI 469 ++ +PE F+P+ F PE T +R Y+Y+PF AGPR CVG R F + Sbjct: 364 FWPEPERFDPERFDPEVTTDRPRYAYVPFGAGPRFCVGNHLGLMEAVFVVAMVSREFDLV 423 Query: 470 SEIPEKEFKLQGDIILKRAEGFQMKVEP 497 + + + + + L+ G M VEP Sbjct: 424 APVGQ-PVVAEPMLSLRVRGGLSMTVEP 450 Score = 46.0 bits (104), Expect = 0.002 Identities = 28/124 (22%), Positives = 60/124 (48%), Gaps = 2/124 (1%) Query: 24 AQTFGNVIRVWLGSKLIVFLVDADDIEIIL-NSHVHIDKATEYRFFKPWLGEGLLISSGP 82 A +G+ +R+ +GS+ + F D + +L ++ + K + LG+GLL S G Sbjct: 36 AARYGDAVRLGVGSRSLYFFNHPDHAKHVLADNSGNYTKGLGLVHARRALGDGLLTSEGE 95 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILL 141 WR R++I P F + + ++ ++ +L++ G+ ++ D + T+ +L Sbjct: 96 LWREQRRVIQPVFQAKRVAGQAHAVAEEADRLIARLRARRGRGPVNLTDEFTALTLGVLG 155 Query: 142 ETAM 145 T + Sbjct: 156 RTLL 159 >UniRef50_A1UDQ6 Cluster: Cytochrome P450; n=10; Mycobacterium|Rep: Cytochrome P450 - Mycobacterium sp. (strain KMS) Length = 474 Score = 119 bits (287), Expect = 2e-25 Identities = 66/174 (37%), Positives = 98/174 (56%), Gaps = 6/174 (3%) Query: 279 MIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ 337 +I +S T + +SD +I E+ M GHDTTA ++ L LG H D+Q RV E Sbjct: 260 LINASDPETGRSLSDDDICNELLVFMLAGHDTTATLLTYALWALGHHPDIQDRVAAEACA 319 Query: 338 IFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTV 397 + DR T D + Y +V+ ESLRL PP + R RDV + Y + AG+ V Sbjct: 320 L---GDRLPTPDDVGRLGYTVQVLNESLRLCPPAAGVGRMALRDVEVD--GYRVEAGSLV 374 Query: 398 VIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 IG + +HR P+ + P F+P+ F PEN ++R + +IPF+ GPR+C+G+ +A Sbjct: 375 GIGIYAVHRDPELWDRPLEFDPERFSPENVKDRDRWQFIPFAGGPRACIGQHFA 428 >UniRef50_Q8UF31 Cluster: Cytochrome P450; n=1; Agrobacterium tumefaciens str. C58|Rep: Cytochrome P450 - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 464 Score = 119 bits (286), Expect = 2e-25 Identities = 58/177 (32%), Positives = 98/177 (55%), Gaps = 5/177 (2%) Query: 276 LDLMIESSQNGTNKI-SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 + +++E+ T ++ SD EI + + T + GH+TTA G ++ LL + + + + +E Sbjct: 239 VSMLLEAKDPETGRMMSDEEIIDNLLTFITAGHETTALGLAWTFHLLSQNPETERKAVEE 298 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + + G P + Y+ +V E++RLYPP PVI R +D + + IPAG Sbjct: 299 IEAVTGGE--PVAAEHIANLAYVRQVFSEAMRLYPPAPVITRTALQDFRLGEHD--IPAG 354 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 T + + + +HR + +PE F+P F PE + RH Y+Y+PF AGPR C+G +A Sbjct: 355 TVLYVPIYAVHRHTALWDEPERFDPSRFEPEKVKARHRYAYMPFGAGPRVCIGNAFA 411 Score = 46.4 bits (105), Expect = 0.002 Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 6/131 (4%) Query: 35 LGSKLIVFLVDADDI-EIILNSHVHIDKATEYR-FFKPWLGEGLLISSGPKWRSHRKMIA 92 LG + V L D I E ++ + + K + R P LG+GLL + G W+ R+ +A Sbjct: 53 LGGVMRVHLADPVLIHEALVKNAALLGKGEDVRRALGPALGQGLLTADGDHWKWQRQSVA 112 Query: 93 PTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM----GIS 148 F L + + + + ++ +S D+ M TT DI++ET M GI Sbjct: 113 AAFRHEKLLELLPVMIETARRTQKRWRSSSTADIDIGHEMMRTTFDIIVETMMSGGYGID 172 Query: 149 RKTQDESGFDY 159 ++S DY Sbjct: 173 IARVEQSITDY 183 >UniRef50_Q89R90 Cluster: Blr2882 protein; n=4; Bacteria|Rep: Blr2882 protein - Bradyrhizobium japonicum Length = 1078 Score = 119 bits (286), Expect = 2e-25 Identities = 64/212 (30%), Positives = 109/212 (51%), Gaps = 4/212 (1%) Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPAT 347 ++ D I+ +++T + GH+TT+ S+ L L H D+ + YDE+ ++FG D + T Sbjct: 255 QLDDVNIRYQINTFLIAGHETTSGLLSYTLYALLKHPDILKKAYDEVDRVFGPDVNAKPT 314 Query: 348 FADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ 407 + ++ Y+ +++ E+LRL+PP P D TI Y + GT + I LHR Sbjct: 315 YQQVTQLTYITQILKEALRLWPPAPAYGISPLADETIGGGKYKLRKGTFITILVTALHRD 374 Query: 408 PKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF 466 P + +P+ F+P+NF E R ++ PF G R+C+GR +A + F Sbjct: 375 PSVWGPNPDAFDPENFSREAEAKRPINAWKPFGNGQRACIGRGFAMHEAALALGMILQRF 434 Query: 467 RTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 + I + L+ + +K EGF++KV PR Sbjct: 435 KLIDH-QRYQMHLKETLTMK-PEGFKIKVRPR 464 >UniRef50_UPI0000D56428 Cluster: PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1) - Tribolium castaneum Length = 713 Score = 118 bits (285), Expect = 3e-25 Identities = 62/174 (35%), Positives = 97/174 (55%), Gaps = 7/174 (4%) Query: 297 EEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKY 356 EE + F G +T+ S VL +LG+ +Q +++ E+ Q+FG S +T + + Y Sbjct: 269 EEAQIMFFVGTETSGVAISSVLLILGMFPQIQEKIFIEIDQVFG-STTGSTLDEINHLDY 327 Query: 357 LERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEV 416 LERVI E+LRL PP+P + R L+ ++ +S + PAG+ V++ M+HR+ ++ +P Sbjct: 328 LERVIKETLRLLPPIPFVMRSLDENLKLSCGTF--PAGSRVIVPIMMVHRREDFWPEPLK 385 Query: 417 FNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTIS 470 F+PD FL E +YIPFS G R+C+G KYA R +R S Sbjct: 386 FDPDRFLEERPSG----TYIPFSYGTRNCLGYKYAMLSMKVILATILRKYRVKS 435 Score = 63.3 bits (147), Expect = 1e-08 Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 3/119 (2%) Query: 25 QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKW 84 +++ V+++W G L V + D+++IL +H H+DK Y + L + W Sbjct: 61 KSYPKVVKIWFGPWLYVSTTEPSDLKVIL-TH-HLDKGEFYELMSEYFRRALAAAPVDLW 118 Query: 85 RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLET 143 + HRK I PTF+ IL +F+G F + + +V+ L+ + D+ + T+D ET Sbjct: 119 KKHRKNINPTFNTTILNTFIGAFAKQAEILVKNLE-KYQSDEDIFPIVWKCTLDSACET 176 >UniRef50_O76107 Cluster: Cytochrome P450; n=2; Culicini|Rep: Cytochrome P450 - Culex quinquefasciatus (Southern house mosquito) Length = 499 Score = 118 bits (285), Expect = 3e-25 Identities = 70/242 (28%), Positives = 123/242 (50%), Gaps = 14/242 (5%) Query: 228 TLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGT 287 T +F++ G + N +SD RD + F +N K F+DL+I+ N T Sbjct: 223 TYRKFSNQIGICVLPN--DVSDFYLGAVRDTIKFRMDNQASRKD---FMDLLIKLEDNFT 277 Query: 288 NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPAT 347 +EI + G++T++ +F L L ++Q++Q R + + R + Sbjct: 278 F----NEIAAQAFVFFQAGYETSSITMTFCLYELALNQELQERARKSVEDVL---KRHGS 330 Query: 348 FA-DTLE-MKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLH 405 F+ +T++ M++L + E+LR YPPV + R++ ++ + + + G VVI + +H Sbjct: 331 FSYETIQDMEFLNCCVKETLRKYPPVANLFREITKNYKVPETDITLEKGYRVVIPVYGIH 390 Query: 406 RQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRN 465 P Y +PEVFNP+ F+PE + NRH +Y+PF GPR+C+G ++A + Sbjct: 391 HDPDIYPNPEVFNPERFIPELSTNRHPMAYLPFGEGPRTCIGERFALMETKIGLSRLLQK 450 Query: 466 FR 467 FR Sbjct: 451 FR 452 Score = 38.7 bits (86), Expect = 0.36 Identities = 30/138 (21%), Positives = 57/138 (41%), Gaps = 3/138 (2%) Query: 12 LTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPW 71 + Q L G FG + +++ L A D+ + + H D+ Y Sbjct: 52 IMQDLYGKLKGSGAKFGGIYSFLKPMVMVLDLDFAKDVLVREFQYFH-DRGMYYNERDDP 110 Query: 72 LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNV--VEKLKSEVGKTFDVH 129 L L+ G KW+S R + PTF +K G + + + +++ E G+ ++ Sbjct: 111 LSAHLVSLEGDKWKSLRTKLTPTFTSGKMKMMFGTIEEVVDRLEGCIRVRVESGECIEIR 170 Query: 130 DYMSGTTVDILLETAMGI 147 D +S +D++ A G+ Sbjct: 171 DIISRFAMDVIGSCAFGL 188 >UniRef50_A7SXR0 Cluster: Predicted protein; n=5; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 481 Score = 118 bits (285), Expect = 3e-25 Identities = 65/185 (35%), Positives = 102/185 (55%), Gaps = 3/185 (1%) Query: 268 GEKKRLAFLDLMI-ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326 G KK L L L E + +G +++D E+ + T + G +TT + LL H D Sbjct: 251 GRKKDLVTLMLEAREDTVDGVPRLNDQELAAQSLTFLLAGFETTTNTLANTAYLLARHPD 310 Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386 VQ ++ EL + + + ++ YL+RVI ESLRLYPP +I R+ + + TI Sbjct: 311 VQDKLIQELDLAGSNRGNSPLYEYSQKIDYLDRVINESLRLYPPGYLIIRRYDEECTIQG 370 Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446 ++ P G V I ++LHR P ++ P+ F+P++F E + RH YS+IPF GPR C+ Sbjct: 371 VHF--PRGVDVNIPVYILHRDPAVWERPDDFDPEHFSHEANEKRHPYSFIPFGMGPRQCI 428 Query: 447 GRKYA 451 G ++A Sbjct: 429 GMRFA 433 Score = 38.3 bits (85), Expect = 0.47 Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 7/172 (4%) Query: 19 LALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPW--LGEGL 76 + + Y + +G V ++++G + + D + ++ I+ H F KP + G+ Sbjct: 54 MLMHYFKAYGRVHKMFIGRAPAIVVSDPEIVKQIVIKEFH-KFPNRPLFIKPNPPMDSGM 112 Query: 77 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 136 + G W+ R + PTF LK V I + + + + E ++ D + S Sbjct: 113 FLGQGALWKRIRTTLTPTFSTAKLKQIVPIIDSRKWPLSPQ-QVERSESTDCVNLFSLFA 171 Query: 137 VDILLETAMGISR--KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFK 186 +D++ +A G+ +T +S F Y +A I R + + SE + K Sbjct: 172 LDVITISAFGVETDIQTDPDSSF-YKLAKKAFRTPIWVRAFSMFPFSEYLSK 222 >UniRef50_UPI0000F21E21 Cluster: PREDICTED: similar to cytochrome P450 CYP4F13; n=1; Danio rerio|Rep: PREDICTED: similar to cytochrome P450 CYP4F13 - Danio rerio Length = 328 Score = 118 bits (284), Expect = 4e-25 Identities = 59/163 (36%), Positives = 96/163 (58%), Gaps = 2/163 (1%) Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPAT-F 348 +++ EIK D MF GHDTTA+ S++ L ++QD Q R E+ + D D + Sbjct: 119 LTNEEIKAHADMFMFAGHDTTASALSWIFYNLAMNQDYQERCRAEVRDLLADRDTHTIGW 178 Query: 349 ADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQP 408 D ++ + I ESLRL+ PV + R ++++ + + VIP G +I + +HR P Sbjct: 179 EDLSQLTFTTMCIKESLRLHSPVLALTRYYSQNMK-TPGDCVIPHGCLCLISIYGVHRNP 237 Query: 409 KYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 + + DP VF+P F P N+ +R +++IPFSAGPR+C+G+ +A Sbjct: 238 QVWPDPLVFDPTRFDPHNSDSRSPHAFIPFSAGPRNCIGQNFA 280 Score = 67.7 bits (158), Expect = 7e-10 Identities = 26/48 (54%), Positives = 35/48 (72%) Query: 65 YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSN 112 Y F KPWLG LL+ SG +W HR+++ P FH +ILK +V IFNQ++N Sbjct: 62 YGFMKPWLGNCLLLQSGQEWSRHRRLLTPAFHFDILKKYVHIFNQSTN 109 >UniRef50_Q1DEH2 Cluster: Cytochrome P450 family protein; n=1; Myxococcus xanthus DK 1622|Rep: Cytochrome P450 family protein - Myxococcus xanthus (strain DK 1622) Length = 467 Score = 118 bits (284), Expect = 4e-25 Identities = 58/178 (32%), Positives = 94/178 (52%), Gaps = 4/178 (2%) Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349 +S++++++E+ T++ GH+TTA + LL H + +AR+ EL + G R Sbjct: 250 LSENQLRDELATMIMSGHETTADALVWAWYLLAQHPEAEARLVAELETVLGG--RLPGAE 307 Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409 D ++Y E V+ E++RLY P + +R+ RD + + +PAGT + + ++ HR + Sbjct: 308 DLPRLRYTEAVVKEAMRLYSPAWITSREALRDCELG--GFHVPAGTMLAVSQWVTHRDAR 365 Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467 Y+ PE F PD +L E+ Q H Y Y PF GPR C+G A R FR Sbjct: 366 YFDAPESFRPDRWLSEDAQRMHRYVYFPFGGGPRFCIGSALAMMETVLITACVARRFR 423 >UniRef50_Q9V4T3 Cluster: Probable cytochrome P450 4ad1; n=2; Sophophora|Rep: Probable cytochrome P450 4ad1 - Drosophila melanogaster (Fruit fly) Length = 516 Score = 118 bits (284), Expect = 4e-25 Identities = 71/207 (34%), Positives = 104/207 (50%), Gaps = 5/207 (2%) Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327 G+ FLD+++ + +G + + EI EEV T +F GHD AA SF L L H ++ Sbjct: 269 GQPINKPFLDVLLTAKLDG-KVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEI 327 Query: 328 QARVYDELYQIFGDS-DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386 Q + +E +IFG++ A A +M YLE +I E+LRLYP VP+IAR NR+ I Sbjct: 328 QQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIAR-TNRN-PIDI 385 Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNF-LPENTQNRHYYSYIPFSAGPRSC 445 + TTV++ + KY+ DP F P+ F P + +PFSAGPR C Sbjct: 386 NGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRRC 445 Query: 446 VGRKYAXXXXXXXXXXXXRNFRTISEI 472 + K+A R F + + Sbjct: 446 IAEKFAMYQMKALLSQLLRRFEILPAV 472 Score = 110 bits (264), Expect = 1e-22 Identities = 51/175 (29%), Positives = 98/175 (56%), Gaps = 2/175 (1%) Query: 41 VFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINIL 100 + L D +I+ IL+S + K Y F +PWLG+GLL SSG +W H+K+ AP F + + Sbjct: 83 MMLSDPAEIQNILSSSSLLYKEHLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSAI 142 Query: 101 KSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFD 158 + ++ + ++ V+KL S+ + FD + ++ T+DI+ E A G + + D Sbjct: 143 EGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGETSD 202 Query: 159 YAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213 A+ +CD++ +R + R + +F+LTS++ +Q + L ++ N++I ++ Sbjct: 203 LHGAIKDLCDVVQERTFSIVKRFDALFRLTSYYMKQRRALSLLRSELNRIISQRR 257 >UniRef50_Q9PWP0 Cluster: Cytochrome P450; n=2; Dicentrarchus labrax|Rep: Cytochrome P450 - Dicentrarchus labrax (European sea bass) Length = 526 Score = 118 bits (283), Expect = 5e-25 Identities = 58/183 (31%), Positives = 99/183 (54%), Gaps = 2/183 (1%) Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329 +K+ F+D+++ S ++D EI+ E +T MF GHDTTA+ + L L H Q Sbjct: 292 QKKKDFVDIILLSRDEDGQGLTDEEIQAEANTFMFAGHDTTASAICWTLYNLARHDQYQE 351 Query: 330 RVYDELYQIFGDSDR-PATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388 + E+ ++ DR + D + + I ESLRL+ PV + RK +D+T+ + Sbjct: 352 KCRQEVMELMEGRDRHEIEWEDLSNLPFTTMCIRESLRLHSPVQAVTRKYTQDMTLPG-D 410 Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 +P G ++ + H P + +P F+P F P N + +++IPFS+GPR+C+G+ Sbjct: 411 CTVPKGAICLVSIYGTHHNPTVWTNPHEFHPLRFDPTNKEGLAAHAFIPFSSGPRNCIGQ 470 Query: 449 KYA 451 K+A Sbjct: 471 KFA 473 Score = 95.1 bits (226), Expect = 4e-18 Identities = 53/179 (29%), Positives = 100/179 (55%), Gaps = 6/179 (3%) Query: 40 IVFLVDADDIEIILNSHVHIDKATE--YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHI 97 +V L D ++ +L + I E Y +PWLG+ LL+S+G +W R+++ P FH Sbjct: 100 LVRLFHPDYVKPLLMAPASITVKDELIYGHLRPWLGQSLLLSNGEEWSRKRRLLTPAFHF 159 Query: 98 NILKSFVGIFNQNSNNVVEKLKSE--VGKT-FDVHDYMSGTTVDILLETAMGISRKTQDE 154 +IL+++V IFN ++N + +K + VG T ++ D+++ T+D LL+ A + Q + Sbjct: 160 DILRNYVAIFNTSTNTMHDKWRHHLAVGTTNLEMFDHITLMTLDSLLKCAFSYNSNCQ-Q 218 Query: 155 SGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213 S +Y A++++ D+I R K + ++ T K+ K L I+H T +V++ ++ Sbjct: 219 STSEYVSAIVELSDLIIDRRQKILHHWDWIYWKTKQGKRFKKALSIVHRFTREVVQKRR 277 >UniRef50_A1WAC7 Cluster: Cytochrome P450; n=1; Acidovorax sp. JS42|Rep: Cytochrome P450 - Acidovorax sp. (strain JS42) Length = 437 Score = 118 bits (283), Expect = 5e-25 Identities = 65/211 (30%), Positives = 112/211 (53%), Gaps = 8/211 (3%) Query: 275 FLDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYD 333 +L +++++ + + + D + +EV T++ GH+TTA+ ++ LL H + +A ++ Sbjct: 213 WLSMLMQARDKASGEPMPDRALLDEVMTLIVAGHETTASTLNWTWYLLARHPEAEAALHA 272 Query: 334 ELYQIFGDSDRP--ATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVI 391 + P A Y+E+V+ E+LRLYPPV + +R+ +D T+ Y + Sbjct: 273 AIANAAPTEAAPDQALATPFASADYVEQVLQEALRLYPPVWLFSRRAVQDDTLG--GYHV 330 Query: 392 PAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 PAGT + I ++LHR ++ PE F P F+P+ RH ++Y+PFSAGPR CVG +A Sbjct: 331 PAGTDIFICPYLLHRDAAQWERPEEFLPARFMPDAAAGRHRFAYLPFSAGPRFCVGAGFA 390 Query: 452 XXXXXXXXXXXXRNFRTI---SEIPEKEFKL 479 FR + +E E EF++ Sbjct: 391 MAEMATHLTMVAERFRWVPVDAEPAEAEFQI 421 Score = 43.2 bits (97), Expect = 0.017 Identities = 28/117 (23%), Positives = 53/117 (45%), Gaps = 5/117 (4%) Query: 45 DADDIE-IILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSF 103 D DDI ++L + + K + LG GL++S G W R+MI P F + F Sbjct: 53 DPDDIRRVLLTNRGNYVKGAGLERVRVLLGNGLIVSDGDLWVRQRRMIQPAFQGQATRGF 112 Query: 104 VGIFNQNSNNVVEK--LKSEVGKTFDVHDYMSGTTVDILLET--AMGISRKTQDESG 156 + Q + +++ + ++ G+ D+ +S ++I+L + R + E G Sbjct: 113 APVVRQVNADLLTRWSAHADSGEPIDLTHELSSVALEIVLRALFSADFDRLVETEGG 169 >UniRef50_A7LFI0 Cluster: Cytochrome P450; n=3; Tribolium castaneum|Rep: Cytochrome P450 - Tribolium castaneum (Red flour beetle) Length = 493 Score = 118 bits (283), Expect = 5e-25 Identities = 66/227 (29%), Positives = 119/227 (52%), Gaps = 9/227 (3%) Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLM--IESSQNGTNKIS-DHEIKEEVDT 301 KT SD + ++ L ++ + R F+DL+ + ++ T+ D++IK Sbjct: 236 KTASDYLINVFKTTLQEREKKKI---IRNDFIDLLSNLRKTETITDSYKFDNDIKMAAQA 292 Query: 302 IMF--EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLER 359 I F G+DTT+ + L +++ +Q R+ E+ +I+ ++ T+ + L MKYL+ Sbjct: 293 IAFFSAGNDTTSITLALTCYELSLNKTIQDRLRHEVTEIYNENGE-FTYENILGMKYLDM 351 Query: 360 VILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNP 419 VI E+LR YP P + RK + T + + G ++++ LH P+YY DPE ++P Sbjct: 352 VISETLRKYPLAPFLNRKSDVKYTFEETGFTLDKGVSIMVPISGLHYDPEYYPDPEKYDP 411 Query: 420 DNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF 466 + F EN +N Y+Y+PF GPR+C+G+++A ++F Sbjct: 412 ERFSDENKKNLTPYTYLPFGEGPRNCIGQRFALLVSKVALASVVKDF 458 >UniRef50_A0NGH0 Cluster: ENSANGP00000031109; n=7; Culicidae|Rep: ENSANGP00000031109 - Anopheles gambiae str. PEST Length = 541 Score = 118 bits (283), Expect = 5e-25 Identities = 64/220 (29%), Positives = 114/220 (51%), Gaps = 8/220 (3%) Query: 287 TNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD-RP 345 T + ++ E+ + G DT + F++ L +++VQ R+Y+E+ +I D +P Sbjct: 320 TREWTEKELVAQCFLFFLAGFDTVSTALGFLMYELMRNREVQERLYEEIAEIDQRLDGKP 379 Query: 346 ATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN---YVIPAGTTVVIGTF 402 T+ M+Y++ V+ ESLRL+PP P++ R NRD T + I G TV++ Sbjct: 380 LTYDAVQGMRYMDMVVSESLRLWPPAPMVDRYCNRDYTFDDGEGLRFKIEKGVTVMVPVA 439 Query: 403 MLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXX 462 LH PKY+ DP+ F+P+ F EN + +Y+PF GPR+C+G ++A Sbjct: 440 GLHSDPKYFPDPKRFDPERFSEENRHKINPGAYLPFGVGPRNCIGSRFALMEVKSIIYYL 499 Query: 463 XRNFRTISEIPEKEFKLQ---GDIILKRAEGFQMKVEPRK 499 ++F T + + L+ ++L +G ++ +PR+ Sbjct: 500 LKSF-TFERCEQTQVPLRLKNSPVVLAAEKGIWIRFKPRE 538 >UniRef50_UPI000065CBAF Cluster: Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS) (Cytochrome P450 5A1).; n=1; Takifugu rubripes|Rep: Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS) (Cytochrome P450 5A1). - Takifugu rubripes Length = 391 Score = 117 bits (282), Expect = 6e-25 Identities = 61/181 (33%), Positives = 98/181 (54%), Gaps = 3/181 (1%) Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349 I++ EI + + G++T++ +F LL I+ + Q + E+ F + P + Sbjct: 205 ITEDEIVGQAFVFLVAGYETSSNTLAFACYLLAINPECQRELQKEVDHFFTRHESP-DYT 263 Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409 + E+KYL+ VI E+LRLYPP AR++ RD ++ +++ P G T I LHR P+ Sbjct: 264 NVQELKYLDMVISETLRLYPPGFRFAREIERDCVVNGQSF--PKGATFEIPAGFLHRDPE 321 Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTI 469 ++ DP+ F P+ F PE +RH + YIPF AGPR+CVG + A R F + Sbjct: 322 HWPDPDKFIPERFTPEAKASRHPFVYIPFGAGPRNCVGMRLAQLEMKMALVRLFRRFNLL 381 Query: 470 S 470 + Sbjct: 382 A 382 Score = 40.7 bits (91), Expect = 0.089 Identities = 25/125 (20%), Positives = 59/125 (47%), Gaps = 5/125 (4%) Query: 34 WLGSKLIVFLVDADDIEIILNSHVHI--DKATEY-RFFKPWLGEGLLISSGPKWRSHRKM 90 +LG K +V + D + + ++ ++ + RF + + LL+ +W+ R + Sbjct: 2 YLGRKPVVVVADPEMLRQVMVKDFSSFPNRMVSFLRFITKPMSDCLLMLRNERWKRVRSI 61 Query: 91 IAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGIS 148 + P F + +K V + N ++ +++ L +E + F++H T+D++ A G Sbjct: 62 LTPAFSASKMKEMVPLINTATDALIKNLDAFAESAEAFNIHKCFGCFTMDVVASVAFGTQ 121 Query: 149 RKTQD 153 +Q+ Sbjct: 122 VDSQN 126 >UniRef50_UPI00015B5352 Cluster: PREDICTED: similar to cytochrome P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 507 Score = 117 bits (281), Expect = 8e-25 Identities = 70/240 (29%), Positives = 114/240 (47%), Gaps = 12/240 (5%) Query: 272 RLAFLDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330 R + L+I++ + K++ +I + G ++T++ F L L + D+Q R Sbjct: 269 RQDMMQLLIQAMKKDDGIKVTMDDIIGQAFFFFLAGFESTSSAMCFALQELAANPDIQDR 328 Query: 331 VYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST---- 386 + E+ T+ + +KYL+ V+ E+LR YPPV + R N++ T Sbjct: 329 LRQEIDDEIEQHGGELTYESLVNLKYLDMVMSETLRKYPPVAITNRLCNKEYTFPPLMEG 388 Query: 387 -KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSC 445 Y + GT+++I F LHR PKY+ DPE F+P+ F EN + Y+Y+PF GPR C Sbjct: 389 YPEYQMEVGTSILISMFGLHRDPKYFPDPEKFDPERFNDENKHKINPYTYMPFGIGPRQC 448 Query: 446 VGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFK----LQGDIILKRAEGFQMKVEPRKRV 501 + ++A R F + + EK + IL EG+ K E RK+V Sbjct: 449 IANRFALMEAKIVIIDILRKF--VVKFTEKSHHPVTLSKKTFILSAEEGYWFKFEGRKKV 506 Score = 34.7 bits (76), Expect = 5.8 Identities = 29/121 (23%), Positives = 52/121 (42%), Gaps = 8/121 (6%) Query: 41 VFLVDADDI-EIILNSHVHIDKATEYRFFK--PWLGEGLLISSGPKWRSHRKMIAPTFHI 97 V + D D I EI + S H + K P +G + G +W+ R + P++ Sbjct: 84 VIIKDPDLIREIFVKSFDHFTDHDAFVTEKMDPIVGRNIFSLRGQRWKEVRNTLTPSYTA 143 Query: 98 NILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETAMGI---SRKTQ 152 +K + + S + V+ E+ + F+ D ++ T D++ A G+ S K Q Sbjct: 144 ARIKMLFALVAECSKDFVQYFVDHPELAENFEAKDAITRYTNDVVASAAFGVKVDSMKDQ 203 Query: 153 D 153 D Sbjct: 204 D 204 >UniRef50_A7DLL5 Cluster: Cytochrome P450; n=1; Methylobacterium extorquens PA1|Rep: Cytochrome P450 - Methylobacterium extorquens PA1 Length = 466 Score = 117 bits (281), Expect = 8e-25 Identities = 62/225 (27%), Positives = 113/225 (50%), Gaps = 5/225 (2%) Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 FL ++ + +SD ++++EV T + GH+TTA S+ + LL H +V + E Sbjct: 241 FLSALMGARDEDGTAMSDRQLRDEVITFLLAGHETTALVLSWTIHLLSRHPEVDRVLATE 300 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + +I R A D +++ E I ES+RLYPP + R+ D I + + G Sbjct: 301 IGEIV--VQRAAAIDDVPRLRFAEHTITESMRLYPPAWAVGREARCDCQIG--GFDVRGG 356 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454 T ++I ++LHR P+++ +PE F P+ + Q ++Y+PF GPR C+G ++A Sbjct: 357 TPILISLWVLHRDPRFFDEPEAFRPERWHQGLAQRLPRFAYMPFGGGPRICIGNRFAMIE 416 Query: 455 XXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 + FR +++ E + + L+ G ++ +E R+ Sbjct: 417 AVLILTTLVQRFRFVADTNEPVVPIP-SMTLRPRGGVRVIIERRE 460 Score = 42.7 bits (96), Expect = 0.022 Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 4/125 (3%) Query: 24 AQTFGNVIRVWLGSKLIVFLVDADDIE-IILNSHVHIDKATEY-RFFKPWLGEGLLISSG 81 ++ +G+V+ +L++ L +IE +++ H + K + R G GLL S G Sbjct: 48 SRQYGDVVAFRTAGQLMLVLTCPREIERVLVKEHQNFPKNEHFWRQVTALFGNGLLTSKG 107 Query: 82 PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILL 141 W+ R++ AP F +L S+ S E ++ G+ DVH M ++ I Sbjct: 108 TFWQRQRRLAAPAFAGPMLASYADAMVHESMLTAEGWRA--GEVRDVHADMMALSLRIAA 165 Query: 142 ETAMG 146 + G Sbjct: 166 KALFG 170 >UniRef50_UPI00005A2E9B Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily A, polypeptide 11; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily A, polypeptide 11 - Canis familiaris Length = 411 Score = 116 bits (280), Expect = 1e-24 Identities = 68/206 (33%), Positives = 108/206 (52%), Gaps = 26/206 (12%) Query: 266 DVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQ 325 +V K+ L FLD+ + +SD +++ EVDT FEGHDTTA+G S++L L H Sbjct: 165 EVRNKRHLDFLDISFFAKMENGRGLSDKDLRAEVDTFKFEGHDTTASGISWILYALATHP 224 Query: 326 DVQARVYDELYQIFGDSDRPATFADTL-EMKYLERVILESLRLYPPVPVIARKLNRDVTI 384 + Q R +E+ + GD F + L +M Y I E+LRLY PVP + R+L++ +T Sbjct: 225 EHQQRCREEIQSLLGDG---LCFREHLDQMPYTTMCIKEALRLYLPVPTVGRELSKPITF 281 Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYYKDPE-------------------VFNPDNFLPE 425 +P G V++ + LH + +PE VF+P F P+ Sbjct: 282 -PDGRSLPRGFLVLLSFYALHHNSNVWPNPEVERKEELDHTYPGPGVPLQVFDPSRFAPD 340 Query: 426 NTQNRHYYSYIPFSAGPRSCVGRKYA 451 +RH ++++PFS G R+C+G+ +A Sbjct: 341 --ASRHSHAFLPFSGGSRNCIGQHFA 364 Score = 45.6 bits (103), Expect = 0.003 Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 5/87 (5%) Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSN----NVVEKLKSEVGKTFDV 128 G GLL+ +G W HR+M+ P FH +ILK +V + + N E+L S+ ++ Sbjct: 71 GYGLLLLNGEIWFQHRRMLTPAFHYDILKPYVRLMVDSVQVMLVNKWEELLSQ-NSHLEI 129 Query: 129 HDYMSGTTVDILLETAMGISRKTQDES 155 +++S T+D +++ A S + ++ S Sbjct: 130 FEHVSLMTLDTIMKCAFRPSDQAEEGS 156 >UniRef50_Q0LLJ2 Cluster: Cytochrome P450; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Cytochrome P450 - Herpetosiphon aurantiacus ATCC 23779 Length = 459 Score = 116 bits (280), Expect = 1e-24 Identities = 62/227 (27%), Positives = 117/227 (51%), Gaps = 5/227 (2%) Query: 276 LDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 L +++ S +G + ++D ++++EV T+ GH+TTA ++ LL +V+ R+ E Sbjct: 228 LSMLLLSIDDGNGQGMTDQQVRDEVVTLFLAGHETTANTLTWCSYLLSQAPEVRQRLQAE 287 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + ++ RP T D ++ Y E VI E+LR+YPP ++ ++ + I+ I Sbjct: 288 VDEVL--QGRPVTLQDLQKLPYTEMVIKETLRMYPPAYALSARVPTE-NITVLGQTITPR 344 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454 ++ + +H P+Y+ +PE F+P+ F PE + RH Y+YIPF AG R C+G +A Sbjct: 345 QAAMVSPYAMHHNPRYWPEPERFDPERFSPEQERARHKYAYIPFGAGSRVCIGNVFAMME 404 Query: 455 XXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRV 501 +++ + P + + I L G ++++ R+ V Sbjct: 405 AQLLLATMMQHYDFTLD-PTQRVEYDPQITLGVKHGLRVRLAQRQPV 450 Score = 40.3 bits (90), Expect = 0.12 Identities = 29/141 (20%), Positives = 61/141 (43%), Gaps = 4/141 (2%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDI-EIILNSHVHIDK-ATEYRFFKPWLGEGLLISS 80 Y +FG+ +G + + D I E+++ + + K + +LG GLL + Sbjct: 32 YLASFGDFTTCRMGPFRVYLVNDPAGIQELLVTNRDKVRKNGGDRELLSRFLGNGLLSND 91 Query: 81 GPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDIL 140 G + RK++ P FH+ ++++ +++ ++E+ G D+ M T+ I+ Sbjct: 92 GADHQKQRKLVQPAFHMKRIQAYAETMVEHTQAMLERWHD--GAILDMDQAMMELTLTIV 149 Query: 141 LETAMGISRKTQDESGFDYAM 161 +T Q+ AM Sbjct: 150 TKTLFNADISEQEVRQVSQAM 170 >UniRef50_Q5W1K7 Cluster: Cytochrome P450 CYP6AY1 protein; n=3; Hemiptera|Rep: Cytochrome P450 CYP6AY1 protein - Nilaparvata lugens (Brown planthopper) Length = 501 Score = 116 bits (280), Expect = 1e-24 Identities = 75/267 (28%), Positives = 124/267 (46%), Gaps = 6/267 (2%) Query: 204 LTNKVIKNKKETYLENKAKGIIPPTLEEFTH---HSGEILANNAKTLSDTVFKGYRDDLD 260 L + + + +T + KA + P L F EI + DT+ R+D+ Sbjct: 205 LMGRRVLDSSQTSVITKAIRVFFPQLFHFLRLRTFPEEIATFFQTVIHDTIENRERNDVQ 264 Query: 261 FNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCL 320 ND + + R D + ++ +I++ I + G++T++ SF L Sbjct: 265 RNDFIPLLMQLRKKSPDY--DGTEANDLEITESVIAAQAFVFFMAGYETSSTTLSFCLYE 322 Query: 321 LGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380 L + DVQ + +E+ ++ + + A +++ YLE ++LE++R YPPV V+AR + Sbjct: 323 LAKNLDVQEKACNEIKKVLNKHGKLSHEA-LMDLDYLEMILLETMRKYPPVSVLARVCTK 381 Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440 TI I GT+V I + H KY+ DPE F+P+ F PEN + Y+Y+PF A Sbjct: 382 PYTIPGTKISIDPGTSVAIPVYSFHHDHKYFPDPETFDPERFSPENQEKSINYTYLPFGA 441 Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFR 467 GP C G K+ R FR Sbjct: 442 GPHVCEGTKFRTGRSGIGLRHLLRLFR 468 Score = 37.1 bits (82), Expect = 1.1 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 4/92 (4%) Query: 81 GPKWRSHRKMIAPTFHINILKSFVGIF----NQNSNNVVEKLKSEVGKTFDVHDYMSGTT 136 G KWR R+ I+P F LK+ + +Q SN + L + ++ D M+ T Sbjct: 121 GEKWRMLRQKISPVFTSGKLKAMFPLLETCSSQLSNYIESALGEQDSSLLEMRDVMARFT 180 Query: 137 VDILLETAMGISRKTQDESGFDYAMAVMKMCD 168 D++ A G+ + E D+ + ++ D Sbjct: 181 TDVIGSVAFGLHFNSFTEKESDFQLMGRRVLD 212 >UniRef50_Q309A5 Cluster: Cytochrome P450 monooxygenase; n=22; Apocrita|Rep: Cytochrome P450 monooxygenase - Apis mellifera (Honeybee) Length = 499 Score = 116 bits (280), Expect = 1e-24 Identities = 68/248 (27%), Positives = 123/248 (49%), Gaps = 15/248 (6%) Query: 257 DDLDFNDENDVGEKKRLAFLDLMIESSQNGTN----KISDHEIKEEVDTIMFEGHDTTAA 312 D + + ++N++ R F+++++E +N K++D I + G +T++ Sbjct: 255 DTIKYRNDNNI---VRPDFINMLMELQKNPQKLENIKLTDSLIAAQAFVFFLAGFETSST 311 Query: 313 GSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVP 372 S L L ++QDVQ ++ +E+ +++ + D EM+YL++V E+LR+YPP Sbjct: 312 TMSNALYELALNQDVQKKLREEINTFCPKNNKELKYDDIKEMEYLDKVFKETLRMYPPAS 371 Query: 373 VIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHY 432 ++ RK D T + IP + I F +HR Y +P+ F+P+ F + +RH Sbjct: 372 ILMRKAISDYTFNDTKITIPKEMKIWIPAFAIHRDSAIYPNPDSFDPERFDQDAMASRHP 431 Query: 433 YSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEK-----EFKLQGDIILKR 487 Y+PF GPR+C+G ++A RN + E+ EK EF G +L Sbjct: 432 MHYLPFGDGPRNCIGARFAVYQTKVGLITILRNHKV--EVCEKTIIPYEFD-PGAFLLSP 488 Query: 488 AEGFQMKV 495 +G +K+ Sbjct: 489 KDGIYLKI 496 >UniRef50_Q27594 Cluster: Cytochrome P450 6a9; n=15; Schizophora|Rep: Cytochrome P450 6a9 - Drosophila melanogaster (Fruit fly) Length = 504 Score = 116 bits (280), Expect = 1e-24 Identities = 65/204 (31%), Positives = 108/204 (52%), Gaps = 12/204 (5%) Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIE-------SSQNGTN-KISDHEIKEEVDTIMFEGH 307 R+ + F ++N++ +R F+D +I+ S++G + ++ E+ + G Sbjct: 254 RETVAFREKNNI---RRNDFMDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGF 310 Query: 308 DTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRL 367 +T++ F L L HQD+Q RV E ++ G + T+ +M YL++VI E+LRL Sbjct: 311 ETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISETLRL 370 Query: 368 YPPVPVIARKLNRDVTI-STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPEN 426 Y +PV+ R+ D + YVI G V+I +HR K Y +P FNPDNF PE Sbjct: 371 YTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPER 430 Query: 427 TQNRHYYSYIPFSAGPRSCVGRKY 450 + R ++PF GPR+C+G ++ Sbjct: 431 VKERDSVEWLPFGDGPRNCIGMRF 454 >UniRef50_Q8T624 Cluster: Cytochrome P450 CYP9L1 protein; n=6; Cellia|Rep: Cytochrome P450 CYP9L1 protein - Anopheles gambiae (African malaria mosquito) Length = 533 Score = 116 bits (279), Expect = 1e-24 Identities = 71/216 (32%), Positives = 108/216 (50%), Gaps = 4/216 (1%) Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATF 348 K+S++E+ + G DT A +FVL + + ++Q R+Y+E+ Q+ D A Sbjct: 317 KLSENEMIAQCLLFFLAGFDTIATSMTFVLYEVTLAPEIQQRLYEEIQQVSETLDGKALT 376 Query: 349 ADTLE-MKYLERVILESLRLYPPVPVIARKLNRDVTI-STKNYVIPAGTTVVIGTFMLHR 406 D L+ M+YL+ V+ E+LR + P P R N+D TI + VIP G TV I LH Sbjct: 377 YDALQGMRYLDMVVSETLRKWSPSPGTDRMCNQDYTIPGDPDIVIPKGATVFIPIAGLHY 436 Query: 407 QPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF 466 P++Y DP+ F+P+ F EN +Y+PF GPR+C+ ++A N+ Sbjct: 437 DPRFYPDPDRFDPERFNDENKHKIPLGAYLPFGIGPRNCIASRFALMEVKAIVYHILLNY 496 Query: 467 R-TISEIPEKEFKL-QGDIILKRAEGFQMKVEPRKR 500 SE KL +G LK G +K PR + Sbjct: 497 ELKRSERTSVPVKLAKGFSPLKPENGMYLKFNPRMK 532 Score = 39.9 bits (89), Expect = 0.16 Identities = 18/68 (26%), Positives = 36/68 (52%) Query: 80 SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDI 139 +G +WR+ R ++PTF + ++ + + S+N+V+ L G+ +V D T D+ Sbjct: 129 TGQRWRNVRTTLSPTFTGSKMRQMFAMILECSDNMVQALAHPTGRECEVKDLFIRFTNDV 188 Query: 140 LLETAMGI 147 + A G+ Sbjct: 189 IASCAFGV 196 >UniRef50_Q0IEL1 Cluster: Cytochrome P450; n=6; Culicini|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 511 Score = 116 bits (279), Expect = 1e-24 Identities = 64/219 (29%), Positives = 108/219 (49%), Gaps = 8/219 (3%) Query: 284 QNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD 343 +N +S E+ +V G++T+++ SF L L HQD+QA+V+ E+ + + + Sbjct: 292 KNAIKSLSIDEVTAQVMVFFVAGYETSSSTVSFCLFELARHQDIQAKVHQEIDTVLAEHE 351 Query: 344 RPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFM 403 T+A MKYLE+ + E++R YPPV ++ R+ + I + ++ GT +V+ Sbjct: 352 GNLTYASLASMKYLEQCLEETVRKYPPVAILNRECTKTYRIPETDVIVEKGTPIVVPLMG 411 Query: 404 LHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXX 463 +HR P+Y+ P F PD F Q++ Y+ F AGPR C+G + Sbjct: 412 MHRDPQYFPQPNDFQPDRF-EGGAQSKAYFG---FGAGPRLCIGMRLGILQSKVAVVTLL 467 Query: 464 RNFRTISEIPE---KEFKLQ-GDIILKRAEGFQMKVEPR 498 R F+ PE E +++ IL G Q+ V+ R Sbjct: 468 RKFKFSLANPEDQHTELRMKPRSFILTTEGGIQLVVQQR 506 Score = 34.7 bits (76), Expect = 5.8 Identities = 24/102 (23%), Positives = 45/102 (44%), Gaps = 8/102 (7%) Query: 48 DIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIF 107 D E + +H+D+ T+ P G L G KW++ R + PTF LK + Sbjct: 93 DFEHFHDRGIHVDEETD-----PMSGH-LFALGGVKWKNLRAKLTPTFSSGSLKEMFPLL 146 Query: 108 NQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLETAMGI 147 + + + ++ E+ + +V + + T D++ A GI Sbjct: 147 VEKATVLQKRFLKEIATSEVVEVKELAACYTSDVIASVAYGI 188 >UniRef50_O16156 Cluster: Cytochrome P450 30; n=1; Mercenaria mercenaria|Rep: Cytochrome P450 30 - Mercenaria mercenaria (Northern quahog) (Venus mercenaria) Length = 515 Score = 116 bits (279), Expect = 1e-24 Identities = 98/445 (22%), Positives = 200/445 (44%), Gaps = 40/445 (8%) Query: 28 GNVIRVWLGSKLIVFLVDADDIEIIL--NSHVHIDKATEYRFFKPWLGEGLLISSGPKWR 85 G + ++LG+ + + D D I+ I+ + D+ + + K W + ++SG WR Sbjct: 71 GKIFGLYLGNIPTLVISDTDIIKQIMVKDFSKFTDRVSLVQVTKKWKS-AVSVASGEHWR 129 Query: 86 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT---FDVHDYMSGTTVDILLE 142 R ++PTF ++ ++ ++E L + + F++ +SG T+D++ Sbjct: 130 FLRTTLSPTFTTGKIREMKPYIHKCMKTLLELLSEKTDQNPEGFNIVPNLSGYTLDVICS 189 Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202 T G+ Q + + + + + R +R+ + F + FF + + G + Sbjct: 190 TGFGLDVDAQKDPD---NLIIRYAREFLEFRG----LRNPL-FLVQMFFPDLSSIFGRL- 240 Query: 203 GLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFN 262 L ++ N+ + + K + + H + L + ++ +L Sbjct: 241 -LETNIVSNEAFDFYMSTMKKAFTDRKQAQSKH---------RDLLQLLINTHKGELG-- 288 Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 EN++ + + F + Q G ++D E+ M G+DTTA S+++ L Sbjct: 289 -ENEI-DTEETTFEGM----KQRG---LTDEEVLLNSIIFMVAGYDTTATTLSWIVYDLV 339 Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382 + + Q ++ +E+ G+S+ T+ + +++YL+ V+ E+LR++PP I R DV Sbjct: 340 TNTECQEKLIEEIDAEIGESE--TTYDNVFKLRYLDMVVNETLRMHPPAQRINRLALEDV 397 Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442 I+ I G LH P+Y+++P ++P+ F PEN N + Y+Y+PF GP Sbjct: 398 KIN--GLQILKGMDCTFSILALHYMPEYWENPYKYDPERFAPENQANINQYAYMPFGQGP 455 Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFR 467 R+C+G++ A + FR Sbjct: 456 RNCIGKRLALLEVKATVVVLLQKFR 480 >UniRef50_Q9VGB4 Cluster: Probable cytochrome P450 313a2; n=2; Drosophila melanogaster|Rep: Probable cytochrome P450 313a2 - Drosophila melanogaster (Fruit fly) Length = 493 Score = 116 bits (279), Expect = 1e-24 Identities = 73/242 (30%), Positives = 123/242 (50%), Gaps = 6/242 (2%) Query: 259 LDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318 L+ N EN E + + IE +N +++S E+ E +++ +T+A + L Sbjct: 254 LNSNPENYC-ESELKTVIHRAIELFRN--DEMSLMELGAECSSMVLAAFETSAHTVYYAL 310 Query: 319 CLLGIHQDVQARVYDELYQIFGDSDR-PATFADTLEMKYLERVILESLRLYPPVPVIARK 377 LL + + Q V++E+ + F + T D ++ YL+RV+ E+LRL P VP +R+ Sbjct: 311 VLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRE 370 Query: 378 LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYI 436 D+ +S VIP G T+ I F R Y+ + FNP+NFLPE +RH Y++I Sbjct: 371 TLEDLRLSN-GVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFI 429 Query: 437 PFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496 PFS G R+C+G +Y RN++ + P + + +++K A+ Q+ E Sbjct: 430 PFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSPQLAFE 489 Query: 497 PR 498 R Sbjct: 490 RR 491 Score = 61.7 bits (143), Expect = 4e-08 Identities = 55/233 (23%), Positives = 103/233 (44%), Gaps = 7/233 (3%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY-RFFKPWLGEGLLISSG 81 Y G+ W+G+ IV D E +L S I+++++ +G GLL G Sbjct: 61 YMDKHGSTYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTLQG 120 Query: 82 PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDIL 140 KW + RK + P F ++L SF+ IFN ++ +V S VG+ DV + + I Sbjct: 121 SKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIA 180 Query: 141 LETAMGISRKTQDESGFDYAM-AVMKMCDIIHQRHYKFWMRSEIVFKLTSF----FKQQT 195 +T +G D D + M + + +++++IV KL + + Sbjct: 181 TQTTLGTDVTKDDNFENDAILKTYQSMLRLTIINIFVPFVQNKIVSKLFGLEWLRRRDAS 240 Query: 196 KLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLS 248 + +I+ + +K + + E Y E++ K +I +E F + ++ A+ S Sbjct: 241 AINKMINNILDKKLNSNPENYCESELKTVIHRAIELFRNDEMSLMELGAECSS 293 >UniRef50_Q5U3Q3 Cluster: Cytochrome P450, family 3, subfamily c, polypeptide 1 like, 2; n=4; Danio rerio|Rep: Cytochrome P450, family 3, subfamily c, polypeptide 1 like, 2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 494 Score = 116 bits (278), Expect = 2e-24 Identities = 64/219 (29%), Positives = 111/219 (50%), Gaps = 4/219 (1%) Query: 282 SSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGD 341 +S+ ++DHEI + + G++TT+ SF+L L + D ++ +E+ + F Sbjct: 278 TSEQPVKGLTDHEILSQSFIFILGGYETTSTTLSFLLHNLATNPDCLEKLVEEIDKNF-P 336 Query: 342 SDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGT 401 D P ++ ++M YLE I ES+RL P P + R + T+ IP T V I T Sbjct: 337 LDTPISYDALMKMDYLEMSINESMRLLPTAPRLERVCKK--TVELNGITIPKDTLVAIPT 394 Query: 402 FMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXX 461 ++L+R P+ + P+ F P+ F PEN Y+++PF GPR+C+G ++A Sbjct: 395 YVLNRDPQLWDSPQEFRPERFSPENKSEFLQYAFMPFGLGPRNCIGMRFALMIVKLLVVK 454 Query: 462 XXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500 +NF ++ E + L+ + + +K+ PRKR Sbjct: 455 LLQNF-SLETCKETQIPLELTPVFQPKVPITLKLTPRKR 492 >UniRef50_Q56JT9 Cluster: Cytochrome P450 monooxygenase; n=10; Endopterygota|Rep: Cytochrome P450 monooxygenase - Tribolium castaneum (Red flour beetle) Length = 463 Score = 116 bits (278), Expect = 2e-24 Identities = 92/389 (23%), Positives = 173/389 (44%), Gaps = 39/389 (10%) Query: 69 KPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDV 128 +P L E L G KW+ R ++P F + +K+ + ++ + N V+ + + ++ Sbjct: 69 EPLLSEALTNLPGEKWKEMRATLSPAFTSSKIKNMYSLISECAENFVDFFQGRE-QDVEI 127 Query: 129 HDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLT 188 + S + D++ A GI + E ++ + + K ++ + +V K+ Sbjct: 128 KEVFSRFSNDVIATAAFGIRVNSVQEPNNEFYAMGRSLTTFSAFQILKIFL-AHLVPKIA 186 Query: 189 SFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLS 248 FF+ +V+ K + E G+I L+ E + L Sbjct: 187 EFFEY-------------RVLPRKVTDFFE----GLI---LDNMQKREAEKIVR--PDLI 224 Query: 249 DTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTN----KISDHEIKEEVDTIMF 304 + + + L ++ N+ GE F +E S+ G N +++D +I + F Sbjct: 225 HLLMEARKGKLKHDNSNEGGE----GFAT--VEESEIGKNTKQVELTDEKIVAQALLFFF 278 Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364 G +T + G SF+ L + VQ ++ E+ ++ ++ MKYL++V+ ES Sbjct: 279 AGFETVSTGVSFMAYELATNPHVQKKLQKEIDLTLQENHGKISYNVLQSMKYLDQVVCES 338 Query: 365 LRLYPPVPVIARKLNRDVTIST-----KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNP 419 LRL+PP P R N++ I + + + T V+I F +HR P+Y+ DPE F+P Sbjct: 339 LRLWPPAPQTDRLCNKNFVIEASKPHERTFTVEKDTMVMISMFAIHRDPQYFPDPEKFDP 398 Query: 420 DNFLPENTQNRHYYSYIPFSAGPRSCVGR 448 + F EN +Y+PF GPR+C+ + Sbjct: 399 ERFSDENKAKIVPGTYMPFGVGPRNCIAK 427 >UniRef50_UPI0000D56564 Cluster: PREDICTED: similar to Probable cytochrome P450 6a17 (CYPVIA17); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Probable cytochrome P450 6a17 (CYPVIA17) - Tribolium castaneum Length = 471 Score = 115 bits (277), Expect = 3e-24 Identities = 68/230 (29%), Positives = 115/230 (50%), Gaps = 9/230 (3%) Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 +E G+ R FL +++E + +I+ EI + + G T+ +F L L Sbjct: 238 EERKKGQTGRNDFLQVLVEMEKKF--EITIDEIAAQCFIFLIAGMSTSPTAMTFALYELA 295 Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382 HQD+Q +V ++ + FG T+ EMKYL +V E+LR+YPP + RK R+ Sbjct: 296 RHQDIQEKVRQDIAK-FGK----VTYDSLQEMKYLGQVFDETLRMYPPAAYLNRKCERNY 350 Query: 383 TIST-KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441 I ++ GT V I +H YY DPE F+P++F EN + R ++++PF G Sbjct: 351 EIPDGSGIIVEKGTIVAIPVLGIHYDRDYYPDPEKFDPEHFSEENKRLRPNFAFLPFGEG 410 Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQGDIILKRAEG 490 PR C+G ++ + ++ T+SE + K++ + ++ AEG Sbjct: 411 PRICIGMRFGLMQSKLGLVSLLKRYKFTVSEKTREPLKMKPNSLVLSAEG 460 >UniRef50_A7RQ80 Cluster: Predicted protein; n=5; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 459 Score = 115 bits (277), Expect = 3e-24 Identities = 68/264 (25%), Positives = 133/264 (50%), Gaps = 12/264 (4%) Query: 197 LLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYR 256 +L I+ G+ + V N + + T ++ ++ K + VF + Sbjct: 150 ILRIVFGIESSVQHNYDDPAFVAARSALEASTFQKIAGAVVGMMPKPIKKMFSRVFFSHT 209 Query: 257 DDLDFNDENDVGEKK------RLAFLDLMIES---SQNGTNKISDHEIKEEVDTIMFEGH 307 +L E + KK R LDLM+E+ + ++++ EI + M G+ Sbjct: 210 KELVEMTEKVIAAKKTQENSTRKDILDLMLEAMIDDETKKKRMTEAEIIAQCLIFMIAGY 269 Query: 308 DTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRL 367 + T + +F+ L + D+Q ++ E+ ++ D+D+ ++ E+ YL+ V+ E+LR+ Sbjct: 270 EGTNSALTFICYNLATNPDIQEKLQQEIDSVWTDADQVLSYDILNELSYLDMVVSETLRM 329 Query: 368 YPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENT 427 YPP ++ R + +D I + + G +++ + LH P+ + +PE FNP+ F E Sbjct: 330 YPP-GMLTRAVTQDCVIQGRRF--RKGNAILMDVYSLHHDPELWPEPERFNPERFTAEAK 386 Query: 428 QNRHYYSYIPFSAGPRSCVGRKYA 451 Q+R+ +Y+PFSAGPR+CVG +++ Sbjct: 387 QSRNPCAYLPFSAGPRNCVGMRFS 410 Score = 48.4 bits (110), Expect = 4e-04 Identities = 49/217 (22%), Positives = 95/217 (43%), Gaps = 15/217 (6%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHI--DKATEYRFFKPWLGEGLLISS 80 Y++T+G V ++L + + D D ++ +L H D+ + +P+ + + Sbjct: 30 YSRTYGRVYGLYLFGSPTIVINDPDILKEVLVKEFHSFHDRPAFFPMPEPF-DSMMFFAE 88 Query: 81 GPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVD 138 G W R ++P F + +K + + N + + ++ KL+ +E G+ F+++ T+D Sbjct: 89 GETWHRVRTTVSPIFSAHKMKMVLPLMNNSCDIMMSKLQQAAEKGEPFNMYRMGQSLTMD 148 Query: 139 ILLETAMGISRKTQ---DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTS--FFKQ 193 +L GI Q D+ F A + ++ M + + K+ S FF Sbjct: 149 FILRIVFGIESSVQHNYDDPAFVAARSALEASTFQKIAGAVVGMMPKPIKKMFSRVFFSH 208 Query: 194 QTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLE 230 +L+ +T KVI KK T + K I+ LE Sbjct: 209 TKELV----EMTEKVIAAKK-TQENSTRKDILDLMLE 240 >UniRef50_UPI0000D56E82 Cluster: PREDICTED: similar to Cytochrome P450 9c1 (CYPIXC1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 9c1 (CYPIXC1) - Tribolium castaneum Length = 480 Score = 114 bits (275), Expect = 4e-24 Identities = 66/231 (28%), Positives = 115/231 (49%), Gaps = 12/231 (5%) Query: 276 LDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDEL 335 + LM+E+++ N+++D +I + T F G +T A SF+ L IH ++Q ++ E+ Sbjct: 254 IHLMLEANKGQANQLTDDDIVAQAMTFFFAGFETVATACSFMAYELAIHPEIQQKLQAEI 313 Query: 336 YQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY-----V 390 + G T+ L MK+L++V+ ESLRL+PP I R + I KN+ V Sbjct: 314 DSVGG-----VTYESLLSMKFLDQVVSESLRLWPPGFQIERMCTKSYKIEPKNHNEKGIV 368 Query: 391 IPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKY 450 + G +++I LH P + +P+ F+P+ F N SY+PF GPR+C+ ++ Sbjct: 369 LEEGVSLIIPVIALHHDPDLFPEPDRFDPERFSEANRSQIVPGSYLPFGVGPRNCIASRF 428 Query: 451 AXXXXXXXXXXXXRNFRTIS-EIPEKEFKLQ-GDIILKRAEGFQMKVEPRK 499 A F + + + KL + L+ +GF++ + PRK Sbjct: 429 ALLEIKTLFFHMLSKFDIVPIDTTQIPLKLSTKKMHLEPEKGFRLGIRPRK 479 Score = 47.2 bits (107), Expect = 0.001 Identities = 23/78 (29%), Positives = 38/78 (48%) Query: 70 PWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVH 129 P LG+ LL+ +G W+ R ++P + N LK+ + + + N V K D+ Sbjct: 106 PILGKSLLMLNGQDWKQMRATLSPAYTTNKLKNMHQLMTECAQNFVGHFKGREKVAVDMK 165 Query: 130 DYMSGTTVDILLETAMGI 147 D + T D++ TA GI Sbjct: 166 DIFTRFTTDVIASTAFGI 183 >UniRef50_Q178V0 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 502 Score = 114 bits (275), Expect = 4e-24 Identities = 70/242 (28%), Positives = 123/242 (50%), Gaps = 5/242 (2%) Query: 260 DFNDENDVGEKKR-LAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318 D N+++D + +R F+D ++ S N IS + E++ TIM G+DT+A + Sbjct: 264 DENEDDDGYQIRRPKLFIDQVL-SGNNTEADISTQNLSEQILTIMAAGYDTSANMVAHSC 322 Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKL 378 L I ++Q +V E+ + D ++ T ++ YL++ E LRL P IAR Sbjct: 323 LFLAIFPELQEKVAQEIQTVLPDCEQELTAETLKDLPYLDKFFKECLRLTPVGSTIARVN 382 Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKD-PEVFNPDNFLPENTQNRHYYSYIP 437 D+ + IP G + ++LHR+ + E F+P+NF PE ++ RH ++++P Sbjct: 383 MTDIELDGCR--IPKGNIFIFNFYVLHRRKDIWGPYAEQFDPENFSPERSKGRHPFAFLP 440 Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 FS G R+C+G +YA RNFR ++I ++ K + ++ L A + +E Sbjct: 441 FSGGSRNCIGARYAMISNKIMIIHLVRNFRMSTKIRFEDLKYRINVTLNLAFKHLITLEA 500 Query: 498 RK 499 R+ Sbjct: 501 RR 502 Score = 60.1 bits (139), Expect = 1e-07 Identities = 34/118 (28%), Positives = 63/118 (53%), Gaps = 3/118 (2%) Query: 34 WLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAP 93 WLG +L+ ++ + ++ +L +K Y F + L GL + W+ +RK + P Sbjct: 74 WLGPQLMFYVAHPELVQKVLTDPNCSEKPFFYEFSR--LTHGLFSAKYSIWKPNRKALNP 131 Query: 94 TFHINILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTVDILLETAMGISRK 150 T ++ +L SFV IF + S ++VEKLK G D+ D+ + ++++ T +G + K Sbjct: 132 TMNVKMLNSFVPIFERFSRSMVEKLKCYPEGTPVDILDFTTECALEMVCGTTLGTALK 189 >UniRef50_A7RSL1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 510 Score = 114 bits (275), Expect = 4e-24 Identities = 57/184 (30%), Positives = 99/184 (53%), Gaps = 6/184 (3%) Query: 272 RLAFLDLMIESSQN----GTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327 R LDLM+E++ + G +S I + GH+TT++ +F L + + Sbjct: 282 RKDMLDLMLEAAASDNTDGGKALSLDAIIANTIVFLLAGHETTSSTIAFASYFLAKNPKI 341 Query: 328 QARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387 Q ++ E+ ++ + ++ ++ YLE VI E+LRL PP + R+ + I+ Sbjct: 342 QEKLQQEIDSVWSGEEEMPSYDTVHDLPYLEMVISETLRLCPPGFAVIRECTKTCIINKL 401 Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447 IP G+ V+ + +HR PKYY DP++F+P+ F PE +R Y+Y+PF GP +C+G Sbjct: 402 R--IPQGSRVLASVYSIHRDPKYYPDPDIFDPERFSPEGKASRDPYAYMPFGHGPHNCIG 459 Query: 448 RKYA 451 ++A Sbjct: 460 MRFA 463 Score = 50.8 bits (116), Expect = 8e-05 Identities = 35/133 (26%), Positives = 61/133 (45%), Gaps = 2/133 (1%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82 Y Q G IR+ K + + D ++ I+ + F P L + L I G Sbjct: 78 YKQYEGPAIRLSFMGKPSILVKDTALLKAIMVKNFDCFHDRLKADFSPPLDKMLTILPGE 137 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDIL 140 +WR+ R ++P F + LK V + N+ + ++K+ +E G+T DV T+DI+ Sbjct: 138 EWRNLRHALSPNFSAHKLKGMVPLMNKACDVYMKKIACAAETGETIDVMKINPALTLDII 197 Query: 141 LETAMGISRKTQD 153 + A G+ Q+ Sbjct: 198 ISCAFGVESDCQN 210 >UniRef50_Q8WQM9 Cluster: Cytochrome P450 CYP6M1; n=7; Culicidae|Rep: Cytochrome P450 CYP6M1 - Anopheles gambiae (African malaria mosquito) Length = 503 Score = 114 bits (274), Expect = 6e-24 Identities = 56/206 (27%), Positives = 106/206 (51%) Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMF 304 K +S K RD +D+ +N + + + M+ ++N ++ +E+ + F Sbjct: 243 KEVSAFFLKVVRDTIDYRVKNGIQRNDFMDLMIRMLRDTENPEEALTFNEVAAQAFVFFF 302 Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364 G +T++ ++ L L ++ +VQ + + ++ + T+ +MKYL++++ ES Sbjct: 303 AGFETSSTLLTWTLYELALNPEVQEKGRQCVQEVLAKHNGEMTYDAIHDMKYLDQILKES 362 Query: 365 LRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP 424 LR YPPVP+ R +D + + VI AGT + I F + R + +PE F+P+ F Sbjct: 363 LRKYPPVPMHFRMTAQDYRVPDTDSVIEAGTMLFIPIFSIQRDASLFPEPEKFDPERFSA 422 Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKY 450 E RH +++ PF GPR C+G ++ Sbjct: 423 EEEAKRHPFAWTPFGEGPRVCIGLRF 448 >UniRef50_Q8MZK0 Cluster: Cytochrome P450; n=6; Culicidae|Rep: Cytochrome P450 - Anopheles gambiae (African malaria mosquito) Length = 505 Score = 114 bits (274), Expect = 6e-24 Identities = 61/211 (28%), Positives = 101/211 (47%), Gaps = 1/211 (0%) Query: 281 ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG 340 + + G K++ E+ + F G +T++ SF L L + D+Q RV E+ + Sbjct: 286 DETTEGLQKLTLDEVAAQAFVFFFAGFETSSTTLSFALFELANNPDIQERVRAEMLEKLQ 345 Query: 341 DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIG 400 D T+ EM YL++VI E+LR+YPPVP + R + + N + T ++I Sbjct: 346 LHDGKITYDALKEMTYLDQVINETLRMYPPVPQLIRVTTQPYKVEGANVSLEPDTMLMIP 405 Query: 401 TFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXX 460 + +H Y DPE F+PD F T RH ++++PF GPR+C+G ++ Sbjct: 406 IYAIHHDASIYPDPERFDPDRFALAATHARHTHAFLPFGDGPRNCIGMRFGLLEVKFGIV 465 Query: 461 XXXRNFR-TISEIPEKEFKLQGDIILKRAEG 490 R T+SE + ++ + AEG Sbjct: 466 QMVSKLRFTVSERMQMPLRMSKTASILEAEG 496 >UniRef50_Q695H1 Cluster: Antennae-rich cytochrome P450; n=3; Polyphaga|Rep: Antennae-rich cytochrome P450 - Phyllopertha diversa (Pale-brown chafer beetle) Length = 507 Score = 114 bits (274), Expect = 6e-24 Identities = 59/187 (31%), Positives = 96/187 (51%), Gaps = 4/187 (2%) Query: 267 VGEKKRLAFLDLMIESSQNGT---NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323 + R +D++I+ G K + + + G +TT++ S+ L L + Sbjct: 264 IENSSRNDLIDILIKLQTEGDFDGYKFEGNRVIAQAAQFFLAGFETTSSTISYALYELCL 323 Query: 324 HQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383 ++ +Q +V E+ ++ +MKYL +V+ E LR YP +P + RK D Sbjct: 324 NKPIQEKVVTEIKSAL-QQHGSVSYEAIQDMKYLHKVVQEILRKYPVLPFLDRKTTMDWK 382 Query: 384 ISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443 I N + AGT V I F LH PKY+ +P+VF+P+ F E T +R +SYIPF GPR Sbjct: 383 IPGTNITLEAGTPVYIPMFGLHYDPKYFPNPDVFDPERFTEETTNSRPCFSYIPFGGGPR 442 Query: 444 SCVGRKY 450 +C+G ++ Sbjct: 443 NCIGERF 449 >UniRef50_UPI00015B4FBC Cluster: PREDICTED: similar to cytochrome P450 monooxygenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 monooxygenase - Nasonia vitripennis Length = 568 Score = 113 bits (273), Expect = 8e-24 Identities = 60/213 (28%), Positives = 105/213 (49%), Gaps = 1/213 (0%) Query: 256 RDDLDFNDENDVGEKKRLAFL-DLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGS 314 + +++ +N+V + L D+ + S+ G +++D I + G +T++ Sbjct: 323 KQTMEYRKKNNVRRNDFVDLLMDIKDDPSKVGDIEMTDALITAQAFVFFIAGFETSSTTI 382 Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374 S L L ++ VQ ++ +E+ + + + + MKYL +V E+LR YPPV V+ Sbjct: 383 SNALYELALNPSVQEKLREEIIEELANDNGSLKYETIKGMKYLHKVFCETLRKYPPVTVM 442 Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434 RK + T S IP G V I + + R P Y DP+ F+P+ F E+ + RH Sbjct: 443 MRKSMQPYTFSGTKVTIPKGMRVWIPAYAIQRDPAIYPDPDTFDPERFSEESIKQRHPSF 502 Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467 Y+PF GPR+C+G ++A RN++ Sbjct: 503 YLPFGDGPRNCIGARFANYQSKIGIIQVLRNYK 535 >UniRef50_A0NQ01 Cluster: Cytochrome P450; n=1; Stappia aggregata IAM 12614|Rep: Cytochrome P450 - Stappia aggregata IAM 12614 Length = 476 Score = 113 bits (273), Expect = 8e-24 Identities = 64/221 (28%), Positives = 109/221 (49%), Gaps = 5/221 (2%) Query: 279 MIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQI 338 ++E+ +S I E I GH+TTA ++ LL +A++ EL + Sbjct: 260 LLEARDENGEPLSRDAIISEAAVIFMAGHETTANTLAWAWFLLSQCDKSRAKLQAELDTV 319 Query: 339 FGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVV 398 + R TF D + Y + VI E+LRLYPPVP++AR+ D +I K+ +P G+ V+ Sbjct: 320 L--AGRSPTFQDVPNLPYTKAVIEETLRLYPPVPILAREAMADTSIGGKS--VPKGSLVM 375 Query: 399 IGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXX 458 + +++HR P + P+VF+P FL ++ + Y Y+PFS GPR C G ++ Sbjct: 376 VVPWLMHRNPVLWSKPDVFDPGRFLNPKSKKPNKYGYVPFSIGPRICAGLQFGMTEAILS 435 Query: 459 XXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 ++F + + + + L+ E M + PR+ Sbjct: 436 LAILAQDFE-LKLKEGTDVQPVARLTLRPGENLPMTLHPRR 475 Score = 37.9 bits (84), Expect = 0.63 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 8/107 (7%) Query: 69 KPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQN-SNNVVEKLKSEVGKTFD 127 +P LG+GL IS W RK++AP H + ++ F I + + G D Sbjct: 104 QPLLGDGLFISDTETWAKRRKVVAPIIHGSRVRGFAPIMIETIEEKRADWAVQGEGAEVD 163 Query: 128 VHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRH 174 M+ T +I+ T G + G DYA V++ +QRH Sbjct: 164 ALADMAHLTAEIICRTIFG------RQLGKDYAAEVVQGFS-DYQRH 203 >UniRef50_Q9GQM9 Cluster: Cytochrome P450 6l1; n=1; Blattella germanica|Rep: Cytochrome P450 6l1 - Blattella germanica (German cockroach) Length = 503 Score = 113 bits (273), Expect = 8e-24 Identities = 54/158 (34%), Positives = 83/158 (52%) Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349 +S+HE+ + G +TT++ +F + L +H ++Q R+ E+ ++ T+ Sbjct: 283 VSEHEVLGQAMLFFAAGFETTSSAMAFAMYELALHPEIQDRLRTEIQEVTACHGGQVTYE 342 Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409 +M YL+ V+ E LR YPP+ I R D I + VI GT + + LHR Sbjct: 343 GVKKMSYLDMVVSEVLRKYPPMSFIDRVCLHDYHIPGTDVVIEKGTPIFVSLLGLHRDSI 402 Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447 +Y DPE FNP+ F E H +SYIPF GPR+C+G Sbjct: 403 FYPDPEDFNPERFNKEKKSGVHPFSYIPFGDGPRNCIG 440 >UniRef50_Q9VGB5 Cluster: Probable cytochrome P450 313a5; n=2; Drosophila melanogaster|Rep: Probable cytochrome P450 313a5 - Drosophila melanogaster (Fruit fly) Length = 487 Score = 113 bits (273), Expect = 8e-24 Identities = 66/212 (31%), Positives = 110/212 (51%), Gaps = 3/212 (1%) Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIF-GDSDRPAT 347 ++S ++ E I+F DT + + VL L+ + Q V++EL ++F + A+ Sbjct: 276 ELSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEAS 335 Query: 348 FADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ 407 AD ++ L+RV+ E++RL P VP++ R+ + + +S Y IP G T++I F HR Sbjct: 336 HADLEKLVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFY-IPEGVTLMIDIFHTHRN 394 Query: 408 PKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF 466 + FNPDNFLPEN + R YSY+PFS G ++C+G K + RN+ Sbjct: 395 KDIWGPQANAFNPDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNY 454 Query: 467 RTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 + K+ + + +K AE + V+ R Sbjct: 455 MLSTTFLYKDLRFIDNTTMKLAEQPLLAVKRR 486 Score = 45.6 bits (103), Expect = 0.003 Identities = 41/199 (20%), Positives = 88/199 (44%), Gaps = 4/199 (2%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY-RFFKPWLGEGLLISSGPKWR 85 +G + W+G ++ + +E I S ++++ + LG GLL W Sbjct: 64 YGKTVLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWN 123 Query: 86 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILLETA 144 RK++ P+F N + SFV + N +N +V L V G ++ ++ + I + Sbjct: 124 ERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINLLPELNKWSFKIAAQIT 183 Query: 145 MGISRKTQ-DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHG 203 MG + Q + + + + ++I W+R++ + KL S+ K++ + + Sbjct: 184 MGDEVRNQANYQNGNLLESYKALNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSNA 243 Query: 204 LTNKVIKNKKETYLENKAK 222 +I +KK + +N ++ Sbjct: 244 FIKDII-DKKLSSTDNSSE 261 >UniRef50_Q0LL77 Cluster: Cytochrome P450; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Cytochrome P450 - Herpetosiphon aurantiacus ATCC 23779 Length = 446 Score = 113 bits (272), Expect = 1e-23 Identities = 57/162 (35%), Positives = 92/162 (56%), Gaps = 4/162 (2%) Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349 ++D ++++E+ T+ GH+TTA ++ LL H + ++ DE+ G R T Sbjct: 243 MTDTQVRDELMTLFLAGHETTANALTWTWYLLAHHPHIATKIKDEVDSTVGT--RLPTMD 300 Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409 D ++ Y +V ESLRLYPPV +IARK ++ + + Y +P G V+ + +HR+ Sbjct: 301 DLSKLPYTLQVFKESLRLYPPVYMIARKASQAFELGS--YHVPEGMAFVVSPYTIHRRAD 358 Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 Y+ PE FNPD F + + +YIPFS GPR+C+G +A Sbjct: 359 YFDHPEDFNPDRFDTSHEASIPKNAYIPFSLGPRNCIGNHFA 400 Score = 45.2 bits (102), Expect = 0.004 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 4/124 (3%) Query: 34 WLGSKLIVFLVDADDIEIILNSHVH-IDKATEYR-FFKPWLGEGLLISSGPKWRSHRKMI 91 +LGS +VF+ A+ IL H ++K+ R + +P LG GLL S R RK++ Sbjct: 44 YLGSYPVVFINSAEYAHGILVQHAQSVEKSLMLRKYMRPLLGNGLLTSENSFHRRQRKLV 103 Query: 92 APTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKT 151 AP F + ++ + ++ + + G+ D+ M T+ ++ +T T Sbjct: 104 APAFQHRHIANYANTISAYTDET--QARWHQGQRIDIAQEMMRLTLRVMSQTLFSTDINT 161 Query: 152 QDES 155 + ++ Sbjct: 162 EADA 165 >UniRef50_Q8MTC8 Cluster: Cytochrome P450 monooxygenase CYP321A1; n=1; Helicoverpa zea|Rep: Cytochrome P450 monooxygenase CYP321A1 - Heliothis zea (Corn earworm) (Bollworm) Length = 499 Score = 113 bits (272), Expect = 1e-23 Identities = 64/217 (29%), Positives = 106/217 (48%), Gaps = 12/217 (5%) Query: 271 KRLAFLDLMIESSQNGTNK--ISDHEIKEEVDTIMFE-------GHDTTAAGSSFVLCLL 321 KR F DL ++ +NGT K + +E++ + + G + A G LL Sbjct: 260 KRHDFADLCVQLQKNGTLKDQATGYELEPTTGLLSAQAFFFFTAGVEPAADGIFATFALL 319 Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381 H ++ +V+ E+ + F D T+ +M+Y+++V+ ESLR++PP+ + R+ D Sbjct: 320 SQHPEILQKVHQEIDEYFEKYDGKITYDVVCDMEYVDKVLSESLRMFPPIGFLTRQCIHD 379 Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441 + N + GT + + +H PKYY DPEVF+P+ F E N Y+PF G Sbjct: 380 TVLPVGNVKVAKGTKLFTPIYEIHHDPKYYPDPEVFDPERFFKERRPNDDL--YMPFGMG 437 Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFK 478 R+C+G +Y R+F T+ IPE + K Sbjct: 438 NRTCIGARYFKLQLLAAIVHVLRSF-TLKPIPESQQK 473 Score = 35.1 bits (77), Expect = 4.4 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Query: 41 VFLVDADDIEIILNSHVHIDKATEYRFFK-PWLGEGLLISSGPKWRSHRKMIAPTFHINI 99 +F++DA +++ +L+S + L E + + +GPKW+ RK + P F + Sbjct: 82 LFVIDAKNVQHVLSSDFQSFNHRGLDSVEGDQLTESITLLNGPKWKLMRKTMTPLFTSSK 141 Query: 100 LKSFVGIFNQNSNNVVEKLKSE 121 LK+ I ++ + + V LK + Sbjct: 142 LKNMYYIMDKCAQDFVTYLKRD 163 >UniRef50_UPI0000D576F6 Cluster: PREDICTED: similar to Probable cytochrome P450 6a20 (CYPVIA20); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Probable cytochrome P450 6a20 (CYPVIA20) - Tribolium castaneum Length = 487 Score = 113 bits (271), Expect = 1e-23 Identities = 65/247 (26%), Positives = 119/247 (48%), Gaps = 7/247 (2%) Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMF 304 K D K ++ + +END + + F IE Q N +S +EI + Sbjct: 237 KETEDFFVKIVTKNIKYREENDYFRQDMMQFF---IE--QKNANTMSINEIIAQCFIFFI 291 Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364 ++T+ +F L L + D+Q RV E+ + + ++ EMKYL +++ E+ Sbjct: 292 AAYETSTTTLTFALYELAQNLDIQDRVRREITSVLLKHQK-YSYEAIAEMKYLNQIVDET 350 Query: 365 LRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP 424 +R YPP + R+ +D TI ++ I G +I +H + Y +P+ F+PD F Sbjct: 351 MRKYPPFLYVVRRCTKDYTIPGEDVTIKKGIFALISILGIHHDEEIYPNPQKFDPDRFSK 410 Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQGDI 483 EN + RH Y+Y+PF GPR C+G+++A ++ T++E + +++ D Sbjct: 411 ENKKMRHPYAYLPFGEGPRICIGKRFALMQIKFGLAALLEKYKFTLNEKTKVPLEIRTDT 470 Query: 484 ILKRAEG 490 ++ +G Sbjct: 471 LVVAPKG 477 >UniRef50_A1ZWE3 Cluster: Cytochrome P450 family protein; n=1; Microscilla marina ATCC 23134|Rep: Cytochrome P450 family protein - Microscilla marina ATCC 23134 Length = 451 Score = 113 bits (271), Expect = 1e-23 Identities = 63/215 (29%), Positives = 107/215 (49%), Gaps = 6/215 (2%) Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 L +++ S T K+S+ ++++EV T+ GH++++A ++ LL + D+ +V E Sbjct: 232 LSMLMHSEDEDTGEKMSNQQLRDEVMTLFMAGHESSSAALGYLFWLLSQYPDIDQKVEAE 291 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 L Q G + TF ++ Y +VI E LRLYPP + RK D I Y +PAG Sbjct: 292 LAQNLGSA--AFTFESMRQVPYSSQVINEMLRLYPPAWTVGRKAVADDEID--GYHVPAG 347 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454 T+++I +++HR ++ P F P+ + + + ++Y PF GPR C+G ++A Sbjct: 348 TSIMIPAYVVHRDADLWEQPHEFLPERWQTQQVKELPRFAYFPFGGGPRLCIGDQFALLE 407 Query: 455 XXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAE 489 R F T P LQ I ++ E Sbjct: 408 IHAVLALLKRRF-TFEHQPRHHIALQPLITMRPVE 441 Score = 41.5 bits (93), Expect = 0.051 Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 10/127 (7%) Query: 54 NSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNN 113 N + H KA EY K LG GL+ + G WR R+M P FH K+ + + Sbjct: 68 NKNYHKGKAFEY--MKVLLGNGLVTNEGDFWRKQRRMAQPAFH----KTKLAGLTEVMTG 121 Query: 114 VVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQR 173 ++E+ E + + D ++ T LL A+ I K +S + A+ K+ D ++ Sbjct: 122 LIEEFLDEWEQKYQSGDRINLTKEMNLL--ALKIVSKALFQS--EVGEAIYKIGDHLNYA 177 Query: 174 HYKFWMR 180 Y+ MR Sbjct: 178 LYRMMMR 184 >UniRef50_Q9BID0 Cluster: Cytochrome P450; n=27; Culicidae|Rep: Cytochrome P450 - Anopheles gambiae (African malaria mosquito) Length = 501 Score = 113 bits (271), Expect = 1e-23 Identities = 58/219 (26%), Positives = 106/219 (48%), Gaps = 8/219 (3%) Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIESS--QNGT-----NKISDHEIKEEVDTIMFEGHD 308 +D ++F N+V + L M++ Q+GT ++I+ ++ + G + Sbjct: 250 KDTVEFRQINNVQRNDFMMLLMKMLKEQMEQDGTAGDLKDRITIEDVAAQAFVFFLAGFE 309 Query: 309 TTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLY 368 T++ SF L L ++Q++Q + + + T+ EMKY+E I ES+R Y Sbjct: 310 TSSTAMSFCLYELALNQELQDKARQNITDVMKQHSS-ITYEAVHEMKYIEMCINESMRKY 368 Query: 369 PPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQ 428 PP+ + R++ +D + + V+ G I + LH P+++ +PE F+PD F E Sbjct: 369 PPITTLTRRVEKDYRVPDTDKVLQEGIMAAIPVYALHHDPEHFPNPEQFDPDRFTAEQEA 428 Query: 429 NRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467 RH + Y+PF GPR C+G ++ ++FR Sbjct: 429 KRHPFVYLPFGEGPRICIGLRFGMMQARIGLVYLLKHFR 467 >UniRef50_P33270 Cluster: Cytochrome P450 6a2; n=10; Diptera|Rep: Cytochrome P450 6a2 - Drosophila melanogaster (Fruit fly) Length = 506 Score = 113 bits (271), Expect = 1e-23 Identities = 74/240 (30%), Positives = 114/240 (47%), Gaps = 16/240 (6%) Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVD---------TIMFEGHDTTAAGSSFVLCLL 321 KR F++L+IE Q G + + E+ E +D G +T+++ S+ L L Sbjct: 267 KRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYEL 326 Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARK-LNR 380 +QD+Q R+ +E+ + + + T+ M YL +VI E+LRLY VP + RK LN Sbjct: 327 AQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALND 386 Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440 V + VI GT V+I HR Y +PE F+P+ F PE R ++PF Sbjct: 387 YVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGD 446 Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRT----ISEIPEKEFKLQGDIILKRAEGFQMKVE 496 GPR+C+G ++ FR +EIP K + I+L G ++VE Sbjct: 447 GPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPM--SIVLGTVGGIYLRVE 504 >UniRef50_UPI0000E473EA Cluster: PREDICTED: hypothetical protein; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 511 Score = 112 bits (269), Expect = 2e-23 Identities = 71/234 (30%), Positives = 121/234 (51%), Gaps = 10/234 (4%) Query: 268 GEKKRLAFLDLMIESSQN--GTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQ 325 GE+ L ++++SQ+ G E+ +E T G +TT+ SF L +LG H Sbjct: 284 GEELPNDMLTNILQASQDLEGNENFGIDEMLDEFVTFFIAGQETTSNLMSFTLEMLGKHP 343 Query: 326 DVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIS 385 V +V DEL + G S +F D ++ YL V+ ESLR+Y P PV+ R +V S Sbjct: 344 HVLQKVQDELDEKLG-SQMFISFQDMGKLDYLMLVLKESLRMYAPAPVVTRVTGTEVKAS 402 Query: 386 TKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHY-YSYIPFSAGPRS 444 T +IP G+ + + F++ R +Y++DP VF P+ F+ +++H Y+Y PF+ G RS Sbjct: 403 T-GLIIPKGSQLNLSPFVMGRMSEYFEDPLVFRPERFV----ESKHSPYAYFPFALGQRS 457 Query: 445 CVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 C+G+++A + F+ +P + + L + ++ +G + V R Sbjct: 458 CIGQQFALIEARIIMAKLLQQFK-FDLVPGQNWNLSYAVTIRPDDGCRNYVSLR 510 Score = 54.0 bits (124), Expect = 9e-06 Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 9/176 (5%) Query: 14 QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDI-EIILNSHVHIDKATEYRFFKP-- 70 Q ++L + + + +G V + + + IV D D + EI+ + VH+ Y Sbjct: 70 QNKLDLLVKWQEEYGTVFKYSILHRYIVAAFDPDVVKEILSKTSVHLKPYRPYGIMAQVL 129 Query: 71 ---WLGEGLLISSG-PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTF 126 ++G GL+ + +W+ HR M+ P+FH L + V FN +++++V L Sbjct: 130 GSRFMGNGLITEANHARWKVHRAMLNPSFHRKYLVTMVDTFNASADHLVNYLMERADGLQ 189 Query: 127 DV--HDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMR 180 +V +D + T+DI+ + + D+ + +++ + I WM+ Sbjct: 190 EVRMYDAFNNITLDIIAKVTFNMELNIIDDPDNPFPNSILTCLNAIMTSINNPWMQ 245 >UniRef50_Q70AR8 Cluster: Putative cytochrome P450; n=1; Streptomyces peucetius|Rep: Putative cytochrome P450 - Streptomyces peucetius Length = 484 Score = 112 bits (269), Expect = 2e-23 Identities = 62/174 (35%), Positives = 95/174 (54%), Gaps = 5/174 (2%) Query: 278 LMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ 337 L + Q G ++SD ++++EV T+ G++TTA + LL H + + +V E+ + Sbjct: 262 LNAQDEQTG-ERMSDKQLRDEVVTMFLGGYETTALSLVWAFSLLSRHPEAERKVRSEVAE 320 Query: 338 IFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTV 397 + GD + PA +D ++YL E LRLYP V ++R D I Y IPAG+ V Sbjct: 321 VCGDRE-PAA-SDLPRLRYLRAFYQEVLRLYPSVWTLSRSPLEDDEIG--GYHIPAGSQV 376 Query: 398 VIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 I +++HR P ++++PE F P+ F T Y+YIPFS GPR C G A Sbjct: 377 FISPYLMHRHPGFWENPEGFRPERFEKSATGGAPLYAYIPFSRGPRLCPGSSVA 430 Score = 37.1 bits (82), Expect = 1.1 Identities = 31/138 (22%), Positives = 62/138 (44%), Gaps = 5/138 (3%) Query: 11 NLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFL-VDADDIEIILNSHV--HIDKATEYRF 67 +L + LV + +G+++ L K +FL V D I+ +L+ + Sbjct: 46 DLVRDLVGTFTRAWREYGDIVSFRLPGKRNLFLIVHPDHIKHVLDDRQPNYPKDPLSVGK 105 Query: 68 FKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--T 125 F+PW+G+GL S+G R++ P F + + F + ++++V + T Sbjct: 106 FEPWVGQGLFTSNGDFHFRQRRLAQPAFKGSRISGFGPAMVEATSDLVRDWHGRATREET 165 Query: 126 FDVHDYMSGTTVDILLET 143 FD+ M + I+++T Sbjct: 166 FDITPEMFRLALTIVMQT 183 >UniRef50_UPI0000DB7562 Cluster: PREDICTED: similar to Probable cytochrome P450 6g2 (CYPVIG2); n=1; Apis mellifera|Rep: PREDICTED: similar to Probable cytochrome P450 6g2 (CYPVIG2) - Apis mellifera Length = 507 Score = 111 bits (268), Expect = 3e-23 Identities = 67/194 (34%), Positives = 98/194 (50%), Gaps = 13/194 (6%) Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAG---SSFVLC 319 D ++ + KR +D ++E N D + K E D ++ + AG S ++C Sbjct: 266 DNREITKTKREDLIDSLMELK----NAKQDKDFKFEGDALLSQSAIFFIAGRETSISIIC 321 Query: 320 L----LGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIA 375 L L H ++Q R +E+ + + T+ MKYL +V+ E LR+YPP P+I Sbjct: 322 LTLYELAKHPEIQKRTREEINEKL--KEHGMTYEGVQSMKYLHQVVSEILRIYPPTPIID 379 Query: 376 RKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSY 435 R D I + VI GT+V I LH PKY+ DP FNPD F EN +N ++Y Sbjct: 380 RVAVADYKIPGTDIVIEKGTSVFIVLTALHNDPKYHPDPLRFNPDRFSDENKENIKPFTY 439 Query: 436 IPFSAGPRSCVGRK 449 IPF GPR C+G + Sbjct: 440 IPFGEGPRICIGAR 453 >UniRef50_Q0LHR9 Cluster: Cytochrome P450; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Cytochrome P450 - Herpetosiphon aurantiacus ATCC 23779 Length = 444 Score = 111 bits (267), Expect = 4e-23 Identities = 64/232 (27%), Positives = 115/232 (49%), Gaps = 8/232 (3%) Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321 +D+ D G+ L+ L L ++ +GT + + ++++E T+ GH+TTA S+ LL Sbjct: 216 HDQRDHGDL--LSMLLLAQDTEGDGTG-MDNQQVRDEAITLFLAGHETTANALSWTWYLL 272 Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381 H + R Y EL ++ + R T D + Y ++ ES+R+YPP ++ R+ D Sbjct: 273 SQHPAIAERWYRELDEVL--AGRIPTMDDVQNLSYTRMILAESIRMYPPAWIMGREALAD 330 Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441 + +Y+ PAG + + F++H +++ + FNP+ + E R +SYIPF G Sbjct: 331 YHVG--DYIFPAGIGLTVSPFVVHHDERWFPNAYQFNPERWTAEQIAQRPKWSYIPFGGG 388 Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQM 493 R C+G ++A + +R + +P LQ I L+ G +M Sbjct: 389 SRICIGEQFAWMEGILLLATIGQRWR-LKLMPGHPVALQPVITLRPRHGIKM 439 Score = 54.4 bits (125), Expect = 7e-06 Identities = 34/121 (28%), Positives = 62/121 (51%), Gaps = 3/121 (2%) Query: 24 AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHI-DKATEYRFFKPWLGEGLLISSGP 82 A+ +G+V+R+ G + ++ L DDI +L ++ I K+ + K LG GLL S G Sbjct: 32 AREYGDVVRLKFGPRELILLNHPDDIHAMLVTNQKILAKSVVLQRSKRLLGNGLLTSEGE 91 Query: 83 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLE 142 + R+++ P FH + + + + + E+ + G+ FDVH M T+ I+ + Sbjct: 92 QHMRQRRLVQPAFHRKRIAGYAEVMANYAAEMREQW--QPGQVFDVHAEMMRLTLRIVAK 149 Query: 143 T 143 T Sbjct: 150 T 150 >UniRef50_A7RMN2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 414 Score = 111 bits (267), Expect = 4e-23 Identities = 62/172 (36%), Positives = 94/172 (54%), Gaps = 11/172 (6%) Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFV-LCLLGIHQD--VQARV 331 FLD+++E+ N +++ I+ EV+T MF GHDT A+G V CL H+ + Sbjct: 251 FLDILLEAEDINGNGLNNENIRAEVNTFMFAGHDTVASGKFSVDWCLDECHRYSYFNNKF 310 Query: 332 YDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVI 391 + L+ F D D M YL + ES+RL+ PVPVI R L+ + I K + Sbjct: 311 KNVLFLFFSCRD------DINNMNYLSMCMKESMRLFSPVPVIGRTLDEEYVIDGKR--V 362 Query: 392 PAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443 P GT V++ + +HR P ++ P++FNP F + + R Y++IPFS GPR Sbjct: 363 PEGTFVLVCIYAVHRNPHVWEKPQMFNPRRFETDTVEGRSAYAFIPFSGGPR 414 Score = 82.6 bits (195), Expect = 2e-14 Identities = 50/193 (25%), Positives = 98/193 (50%), Gaps = 5/193 (2%) Query: 25 QTFGNVIRVWLGS-KLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK 83 + F RVW G + + L D ++ +L+ + ++ Y+F P+LG+GL + G K Sbjct: 42 ERFKTAYRVWFGPLRSALVLCHPDTVKPVLSKNAPKERFF-YKFLFPFLGDGLGLQEGAK 100 Query: 84 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV---GKTFDVHDYMSGTTVDIL 140 W + RK++ P FH +IL+ +V IF +++ +VEK G+ ++ +S T+D + Sbjct: 101 WWNTRKLVTPAFHFDILRRYVPIFQESAKILVEKWSQACGPSGRKVELFQDISLMTLDSV 160 Query: 141 LETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGI 200 L+ A S Q E Y A+ + + R + + +++LT + K + Sbjct: 161 LKCAFSYSSNCQTEGHDKYIKAINGIAKALLDRLLNPFYHFDWLYRLTPARSKFMKYCDL 220 Query: 201 IHGLTNKVIKNKK 213 IH +++VI++++ Sbjct: 221 IHQKSDEVIESRR 233 >UniRef50_UPI0000D577ED Cluster: PREDICTED: similar to Cytochrome P450 6g1 (CYPVIG1) (Cyp6-like protein); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 6g1 (CYPVIG1) (Cyp6-like protein) - Tribolium castaneum Length = 523 Score = 111 bits (266), Expect = 6e-23 Identities = 55/192 (28%), Positives = 94/192 (48%), Gaps = 1/192 (0%) Query: 259 LDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318 LD D+ V K R +D++++ + N I + + G +TT++ F L Sbjct: 279 LDIMDKRSVSNKSRNDLIDILLQMKNDNRNFIEGDILVSQALMFFVAGFETTSSTMGFAL 338 Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKL 378 + D+Q ++ +E+ I D + EM+YL+ + E LR YP VP + RK Sbjct: 339 YEFARNPDIQDKIRNEIKDI-SDKYGDIKYDSLKEMEYLDMCVKEVLRKYPVVPFLDRKC 397 Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPF 438 N TI N I T + I + LH P+Y+ + ++F+P+ F N ++Y+PF Sbjct: 398 NTTYTIPDTNVTIDKDTPIFIPSLALHYDPQYFPNADIFDPERFSSNNKTGIDSFAYLPF 457 Query: 439 SAGPRSCVGRKY 450 GPR+C+G ++ Sbjct: 458 GEGPRNCIGARF 469 >UniRef50_Q0LFI0 Cluster: Cytochrome P450; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Cytochrome P450 - Herpetosiphon aurantiacus ATCC 23779 Length = 457 Score = 111 bits (266), Expect = 6e-23 Identities = 63/225 (28%), Positives = 114/225 (50%), Gaps = 7/225 (3%) Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 LD+++E+ T ++SD +I++EV TI GH+TTA +F LL H +++ + E Sbjct: 238 LDMLLEAQDAETGERMSDEQIRDEVLTIFAAGHETTANTLTFGWYLLSEHCEIRQNLQTE 297 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIA-RKLNRDVTISTKNYVIPA 393 L Q+ R + D ++ Y +V E++RLYP P+ R++ + + Y +P Sbjct: 298 LDQVL--QGRAPSVNDLPQLPYTLQVFKEAMRLYPAAPITGPRRVTKPTQLG--GYDLPL 353 Query: 394 GTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXX 453 + V++ LH P ++++P F+P F P Q RH+ +++PF AGPR C+G A Sbjct: 354 NSQVIVSITNLHLHPAFWENPLQFDPSRFAPNANQPRHHLAFMPFGAGPRKCIGNNLAEM 413 Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 +++ + P + K + I ++ G M ++ R Sbjct: 414 EGALLLACVAQHYNPQLQ-PGHQVKPEMAITMRAKAGMPMLLKRR 457 Score = 35.1 bits (77), Expect = 4.4 Identities = 25/119 (21%), Positives = 55/119 (46%), Gaps = 3/119 (2%) Query: 28 GNVIRVWLGSKLIVFLVDADDIEIILNSHVH-IDKATEYRFFKPWLGEGLLISSGPK-WR 85 G+++R +GS+++ + + D + +L H K + G GL+ + P+ W Sbjct: 45 GDIVRYQIGSRIVHVVSNPDYAQYVLVEHQRDFPKVGGNGGLQIIAGNGLISNPSPESWL 104 Query: 86 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTVDILLET 143 R+M+ P FH L + + ++++ ++ D+ M T+DI+++T Sbjct: 105 IQRRMMQPMFHRKRLAAMGEKIDGAGARMIQRWQALPDAAPIDMDHEMLQVTLDIIMQT 163 >UniRef50_A5FJE6 Cluster: Cytochrome P450; n=1; Flavobacterium johnsoniae UW101|Rep: Cytochrome P450 - Flavobacterium johnsoniae UW101 Length = 448 Score = 111 bits (266), Expect = 6e-23 Identities = 57/177 (32%), Positives = 101/177 (57%), Gaps = 6/177 (3%) Query: 276 LDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 L++++E+ T + +S ++ +E+ + GH+TTA +F L LLG + +VQ ++++E Sbjct: 233 LNMLLETRYEDTGESMSVEQLIDEIKVLFIAGHETTANALTFTLHLLGRNPEVQQKIFEE 292 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + +I +D +M Y V+ ES+RLYPP + R+ D +++ ++ I Sbjct: 293 IIEIESQTDN--VIEQLQKMTYTNAVLNESMRLYPPAWITDRQNLEDDSLA--HFKIKKN 348 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 T + + + LHR PKY+K+P+ F P+ FL + + Y Y PF AGPR C+G +A Sbjct: 349 TLIGVSFYELHRNPKYWKNPDEFIPERFLGDQKKESMQYFY-PFGAGPRMCIGTGFA 404 Score = 42.3 bits (95), Expect = 0.029 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 5/129 (3%) Query: 23 YAQTFGNVIRVWLG-SKLIVFLVDADDIEIIL--NSHVHIDKATEYRFFKPWLGEGLLIS 79 Y G+ + +G SK I+ D + + IL N + + + +LG+GLL S Sbjct: 36 YFDKLGDSFSIRIGFSKYIILSRDNEIAQYILVKNQKNYHKSKFQSVYLSKYLGKGLLTS 95 Query: 80 SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDI 139 G W R++I P FH + V N +E L E K D+ MS ++ Sbjct: 96 DGDFWLKQRRLIQPAFHKQKMNQLVDNMNAVIALELENLIEE--KPIDLFPVMSNLAFNV 153 Query: 140 LLETAMGIS 148 + ++ +S Sbjct: 154 VAKSLFQLS 162 >UniRef50_Q6PW74 Cluster: Cytochrome P450 CYP331A1; n=1; Capitella capitata|Rep: Cytochrome P450 CYP331A1 - Capitella capitata Length = 549 Score = 110 bits (265), Expect = 7e-23 Identities = 107/475 (22%), Positives = 211/475 (44%), Gaps = 39/475 (8%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGE----GLLI 78 ++Q +G+ + G I+ D D ++ I + + +Y +P E + + Sbjct: 63 WSQEYGSTFGYFEGPTPILVSSDLDLLKEIFIKNFNKFHGRKYVPVQPDPAEDKGCSMFM 122 Query: 79 SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTT 136 + G +W+ R + PTF LK + N+ S +++KL++ G + + T Sbjct: 123 AQGQRWKRLRTITNPTFTAAKLKHSTELMNRKSRTLLKKLEAIATKGDKCRILPLLQDLT 182 Query: 137 VDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMR-SEIVFKL---TSFFK 192 +D++ E+A GI Q+ +G + +++++K + F+ E+ F + +FF Sbjct: 183 LDVIGESAFGIEVNAQEIAG-NPSLSMLKRNREQNTLRKSFYATLPELRFTIYHCLAFFA 241 Query: 193 QQTKL--LGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDT 250 + + I+ + KV++ +K N + E T+H G + Sbjct: 242 KFVSVPRFQILESM-GKVLEMRKIQPQRNPPDLMQLMVDAEATNHHGSL----------- 289 Query: 251 VFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTN------KISDHEIKEEVDTIMF 304 + + DD D +D++D + +D+ I + + K++ EIK + + Sbjct: 290 --EIFADDDDDDDDDDYAKASPDESIDIQISEADRERHARTRKKKLTADEIKSQGFLFLL 347 Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364 G++TT+ + L + D Q +Y+E+ I D D T+ + YL+ V+ E+ Sbjct: 348 AGYETTSNTLACCSHALANNPDKQQLLYEEVNSIIQD-DEELTYEKVKALPYLDMVLRET 406 Query: 365 LRLYP-PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY--KDPEVFNPDN 421 LR+YP V+ R+ TI+ + V+P + + +H + DP++F P+ Sbjct: 407 LRMYPIGSQVVTRRCVETCTIN--DLVVPRDMAIHANVWDVHYNANIWGATDPKIFEPER 464 Query: 422 FLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKE 476 FLP+ RH +++PF AGPR+C+G ++A + FR +S KE Sbjct: 465 FLPDRKARRHPLAWLPFGAGPRNCIGLRFALLEAQIVLAKLIKKFRIVSCDQTKE 519 >UniRef50_UPI0000D5650B Cluster: PREDICTED: similar to Cytochrome P450 6a2 (CYPVIA2) (P450-B1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 6a2 (CYPVIA2) (P450-B1) - Tribolium castaneum Length = 485 Score = 110 bits (264), Expect = 1e-22 Identities = 62/220 (28%), Positives = 108/220 (49%), Gaps = 8/220 (3%) Query: 257 DDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSF 316 D + + +END R F+ L+IE + N+++ EI + G +T++A +F Sbjct: 250 DSVKYREENDY---VRSDFMQLLIEMKKQ--NQLTIEEIAAQCFVFFIAGFETSSATLTF 304 Query: 317 VLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIAR 376 L L +Q++Q DE I + T+ ++K+L++V+ E+LR YPP+ + R Sbjct: 305 ALYELAKNQNLQNVARDE---ILANCPNEITYDSLADLKFLDQVVDETLRKYPPLLYVTR 361 Query: 377 KLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYI 436 + ++ I ++ VI GT V I LH ++Y PE F P+ F RH Y+++ Sbjct: 362 QCVKNYKIPDEDVVIEKGTLVAIPISALHSDEEFYPKPETFEPERFSKTEKSLRHPYTFL 421 Query: 437 PFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKE 476 PF GPR C+G+++ +N++ KE Sbjct: 422 PFGEGPRMCIGKRFGLLEVKLALTCLLKNYKFSVNCKTKE 461 Score = 40.3 bits (90), Expect = 0.12 Identities = 41/172 (23%), Positives = 76/172 (44%), Gaps = 18/172 (10%) Query: 34 WLGSKLIVFLVDADDIE-IILNSHVH-IDKATEYRFFKPWLGEGLLISSGPKWRSHRKMI 91 + G I +VD D I+ I+ H +D+ + L L G KW++ R+ + Sbjct: 75 YFGVSPICLIVDPDLIKNIVTRDFEHFVDRGVYFNEKDDPLSGHLANLDGQKWKNMRRKL 134 Query: 92 APTFHINILKSFVGIFNQNSNNVVEKLKS---EVGKTFDVHDYMSGTTVDILLETAMGIS 148 PTF + K+ I N++EK+KS K ++++ +++++ A G+ Sbjct: 135 NPTFSASKTKNMFPIVKFCVENMMEKVKSCYENAHKCCNINEVFPAFSINVICSCAFGL- 193 Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGI 200 Q+E+ A A + + YK+ +V L +FF + K +GI Sbjct: 194 ---QEENALFKAYA----DECVSWTKYKY-----LVQILATFFDKTAKRMGI 233 >UniRef50_A2XB72 Cluster: Putative uncharacterized protein; n=2; Oryza sativa|Rep: Putative uncharacterized protein - Oryza sativa subsp. indica (Rice) Length = 531 Score = 109 bits (263), Expect = 1e-22 Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 9/224 (4%) Query: 281 ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG 340 E+S K++ E+ +E T F GH+TTA S+ L +L H + QA V +E+ ++ G Sbjct: 308 EASAGAERKLTTRELVDECKTFFFGGHETTALALSWTLLMLAAHPEWQAAVREEVVEVAG 367 Query: 341 DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI----STKNYVIPAGTT 396 S P A ++ + V+ E LRLYPP P + R+ +DV + K VIP GT Sbjct: 368 RSG-PLDAAALGKLTKMGCVLSEVLRLYPPSPNVQRQALQDVVVVAGDGEKKVVIPKGTN 426 Query: 397 VVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQN--RHYYSYIPFSAGPRSCVGRKYAXX 453 + I +HR + + ++ F P+ F+ E Q RH Y+PF G R CVGR Sbjct: 427 MWIDVVAMHRDGELWGEEASEFRPERFMREGVQGGCRHRMGYVPFGFGGRICVGRNLTAM 486 Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497 R F + PE + + L+ + G Q+++ P Sbjct: 487 ELRVVLAMVLRRF-AVEVAPEYRHAPRIMLSLRPSHGIQLRLTP 529 Score = 51.6 bits (118), Expect = 5e-05 Identities = 33/140 (23%), Positives = 65/140 (46%), Gaps = 6/140 (4%) Query: 23 YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHI--DKATEYRFFK-PWLGEGLLIS 79 + + FG V WLG++ +++ D + ++ + K +R + P G GL+++ Sbjct: 85 WRRAFGKVFVYWLGTEPFLYVADPEFLKAATAGALGKLWGKPDVFRRDRMPMFGRGLVMA 144 Query: 80 SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKT-FDVHDYMSGTT 136 G +W HR +IAP F L +G+ + + ++ + V G++ DV + Sbjct: 145 EGDEWARHRHIIAPAFSATNLNDMIGVMEETTAKMLGEWGDMVASGRSCVDVEKGVVRNA 204 Query: 137 VDILLETAMGISRKTQDESG 156 +I+ + GIS D +G Sbjct: 205 AEIIARASFGISADDDDATG 224 >UniRef50_Q234S0 Cluster: Cytochrome P450 family protein; n=2; Tetrahymena thermophila SB210|Rep: Cytochrome P450 family protein - Tetrahymena thermophila SB210 Length = 522 Score = 109 bits (263), Expect = 1e-22 Identities = 101/398 (25%), Positives = 173/398 (43%), Gaps = 32/398 (8%) Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHDY 131 G+GL+++ W R ++ +FH N LK+ V I + + + L S+ GKT + + Sbjct: 119 GQGLVVAEEKVWTRQRNFLSNSFHFNALKNRVPIIKEITKEFLSTLPSD-GKTPITIIEE 177 Query: 132 MSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFF 191 + T +++++T G + K +G ++ + K+ + + S F F Sbjct: 178 LQNITSEVVIQTFFGENLKGMTVNGLQPSVEISKIIG----DGFSYKANSFAYFLKLMVF 233 Query: 192 KQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTV 251 Q+ K +++ K + E Y +GI+ L E E L + +K + + Sbjct: 234 GQE-KASRVLNTTFEKNFLKRVENY-NQFIEGIVDKRLSEL-----EKLTDTSK-VDENF 285 Query: 252 FKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTA 311 Y L++ + ++ + D I I EI + T F G DTTA Sbjct: 286 LNLYL--LEYIKQQKALKENPKIYADYEI---------IPKREIVHQFTTFFFAGMDTTA 334 Query: 312 AGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPV 371 + L +L H ++Q ++ E+ + D D +++Y ESLR+YP Sbjct: 335 NQTGICLWVLAQHPELQQKIRAEIDSVIQTFD-DLKHEDLNKLEYFNAFFKESLRVYPTA 393 Query: 372 P-VIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ--PKYYKDPEVFNPDNFLPENTQ 428 P VI R RD + ++ IP G V T + Q P KD + FNPD FL +N Sbjct: 394 PQVIPRVSARDHMVD--DFPIPKGAFVSNLTIQYNEQKFPLLCKDIDTFNPDRFLDKNII 451 Query: 429 NRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF 466 H+ S+IP+SAGPR+C+G+ A +N+ Sbjct: 452 QDHF-SFIPYSAGPRNCIGQHLALIEAKIMIAYILKNY 488 >UniRef50_Q179B9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 506 Score = 109 bits (263), Expect = 1e-22 Identities = 66/247 (26%), Positives = 127/247 (51%), Gaps = 8/247 (3%) Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319 D + E + + K L +D ++ S +G + +D +I++ V ++ DTT+ ++ Sbjct: 262 DVDTEEEYNKPKIL--VDQLLGVSHDG-RQFNDIQIRDNVYAVITGATDTTSLATAHACL 318 Query: 320 LLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLN 379 L + D+Q R++ EL ++F + T + ++ YL+ I E R VP +AR+ Sbjct: 319 FLSFYPDIQERLHAELAEVFPGNIADYTPENIKKLTYLDMFINEVQRHCTVVPYVARENT 378 Query: 380 RDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPF 438 ++ I +P G ++ + +H++P + D E F+P+NF E ++RH +++P+ Sbjct: 379 AEIEID--GVKVPPGNIFIMSLYAMHKRPDIWGPDAEKFDPENFTEERIKDRHPAAFLPY 436 Query: 439 SAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 SAG ++C+G +YA RNF S+I ++ + + D+ LK FQ V+ + Sbjct: 437 SAGSKNCLGWRYAIFGMKLIMIHLVRNFHFSSKIKHEDMQFRHDLTLKLP--FQHLVQLK 494 Query: 499 KRVPTNV 505 KR P + Sbjct: 495 KRNPGKI 501 Score = 55.2 bits (127), Expect = 4e-06 Identities = 49/235 (20%), Positives = 102/235 (43%), Gaps = 13/235 (5%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 ++ W G K+ + D + IL+S +++ YRF +G+ + P W+ +RK Sbjct: 69 ILTAWAGPKMFLITSHPDIVHQILSSPDCLERPFLYRF--AGFTQGIFTAKLPVWKDNRK 126 Query: 90 MIAPTFHINILKSFVGIFNQNSNNVVEK-LKSEVGKTFDVHDYMSGTTVDILLETAMGIS 148 + TF+ I+ FV F + + + L+ G+T ++ Y + +++ T +G Sbjct: 127 RLNSTFNQRIVHGFVPYFVKCCEKMTKSLLECADGETVNIQKYTAVCALEMAAGTTLGGD 186 Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKV 208 Q + ++ + + +R S++++++T +K+ + II K+ Sbjct: 187 VLQQGDGKEEFKRGLDLAFNGASRRMVTVPFYSDLIYQMTHHYKELMEGRRIICDFFTKL 246 Query: 209 IKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFND 263 + +K+ +L + +K T EE+ N K L D + D FND Sbjct: 247 LIERKK-FLLDHSKNTDVDTEEEY---------NKPKILVDQLLGVSHDGRQFND 291 >UniRef50_Q0UKV8 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 536 Score = 109 bits (263), Expect = 1e-22 Identities = 79/247 (31%), Positives = 124/247 (50%), Gaps = 18/247 (7%) Query: 267 VGEKKRLAFLD----LMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 VG+KK A L+ L I S +N SD + +++ T + GH+TT++ ++ LL Sbjct: 287 VGQKKANAKLESKESLDILSIMLRSNNFSDSNLVDQLLTFLAAGHETTSSALTWSGYLLS 346 Query: 323 IHQDVQARVYDELYQIFGD----SDRPATFADTLE-MKYLERVILESLRLYPPVPVIARK 377 H DV+A++ +E+Y+ D SD A LE M YL V E LR+YP VP+ AR Sbjct: 347 THPDVKAKLRNEIYKHIPDPQALSDPAMDVAGLLEGMPYLNAVCNEVLRVYPTVPITARY 406 Query: 378 LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPEN---TQN---R 430 RD I+ IP GT + I + ++R PK + D E F P+ ++ EN T N Sbjct: 407 AVRDTNIA--GQYIPKGTVLFIPPWAINRNPKLWGPDSEKFVPERWIDENGRTTMNGGAD 464 Query: 431 HYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEG 490 Y+++ F GPR+C+G ++A +F P+++ G I K G Sbjct: 465 SNYAFLTFLHGPRACIGERFARAELRALVAALVGSFDFQMAYPDEKVIAAGTITSKPLNG 524 Query: 491 FQMKVEP 497 ++K++P Sbjct: 525 MRLKLQP 531 Score = 48.0 bits (109), Expect = 6e-04 Identities = 30/120 (25%), Positives = 57/120 (47%), Gaps = 5/120 (4%) Query: 32 RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYR-FFKPWLGEGLLISSGPKWRSHRKM 90 R + S ++ A +I+++ ++K R F + +LG+GLL++ G + + HRK Sbjct: 100 RGFFHSNKVIVTSTAALADILVHKSYDMEKPPPVRTFLRKFLGDGLLMTEGDEHKHHRKN 159 Query: 91 IAPTFHINILKSFVGIFNQNS----NNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMG 146 I P FH +K IF S N + ++ + ++ Y + T+DI+ +G Sbjct: 160 IMPAFHFRHIKELYPIFWSKSIEFCNAMGRAIQDNDDRVLEIGHYATQVTLDIIGLAGLG 219 >UniRef50_A1DAX0 Cluster: Cytochrome P450; n=5; Trichocomaceae|Rep: Cytochrome P450 - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 547 Score = 109 bits (263), Expect = 1e-22 Identities = 67/216 (31%), Positives = 112/216 (51%), Gaps = 13/216 (6%) Query: 291 SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFAD 350 +D E+ +++ T + GH+TTA+ ++ LL +H DVQ R+ E+ + + P T++D Sbjct: 328 TDDELVDQMLTFLAAGHETTASALTWACYLLTLHPDVQERLRTEIREHIPSGNHPITWSD 387 Query: 351 TLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKY 410 M L V E LRLYP VP+ R+ RD TI+ K+ +P GT ++I + ++R P++ Sbjct: 388 LESMPLLNGVCQEVLRLYPTVPITIREAVRDTTIAGKH--VPKGTRILICPYAINRSPEF 445 Query: 411 YKD-PEVFNPDNFL--PENTQN--RH------YYSYIPFSAGPRSCVGRKYAXXXXXXXX 459 + D E F P+ ++ +N Q H Y+ I F G RSC+G+ +A Sbjct: 446 WGDNGEEFLPERWIDPDKNGQKVVNHNGGASTNYAQITFLHGQRSCIGKDFARAELRCAV 505 Query: 460 XXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKV 495 FR + P++E + G + K EG +K+ Sbjct: 506 AGVVGRFRFEMQDPKQEIHIAGAVTTKPVEGMHLKM 541 Score = 35.5 bits (78), Expect = 3.3 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 9/67 (13%) Query: 65 YRFFKPW---------LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV 115 Y F KPW +G GL++S G + RK + P F+I ++S + + + + Sbjct: 125 YDFEKPWRAREFLARIIGFGLILSEGAAHKKQRKALTPAFNIKNIRSLYSLMWEKTGLFL 184 Query: 116 EKLKSEV 122 ++L+ E+ Sbjct: 185 DELEKEI 191 >UniRef50_Q70AR1 Cluster: Putative cytochrome P450; n=1; Streptomyces peucetius|Rep: Putative cytochrome P450 - Streptomyces peucetius Length = 448 Score = 109 bits (262), Expect = 2e-22 Identities = 58/181 (32%), Positives = 102/181 (56%), Gaps = 6/181 (3%) Query: 268 GEKKRLAFLDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326 G + L +++ + + T + +SD E+++E+ TI+F G +TTA+ S+ L H + Sbjct: 222 GTSEHNDLLSVLLGARDSETGEYLSDTEVRDELSTILFAGAETTASTLSWTFYQLAEHPE 281 Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386 V+A + E+ + GD RP + D +++ + RV+ E +RL+ V ++ R+ V + Sbjct: 282 VEAELVAEIKDVVGD--RPVSIEDVPKLEAVRRVLDEVIRLHG-VTMLMRRTTAPVELG- 337 Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446 +++P GT V + +HR P Y DP+ F+PD +LPE + +YIPF AG R C+ Sbjct: 338 -GHLLPVGTEVGFSLYAMHRDPTLYDDPDRFDPDRWLPERRGDITRQAYIPFGAGNRKCI 396 Query: 447 G 447 G Sbjct: 397 G 397 Score = 41.5 bits (93), Expect = 0.051 Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 3/117 (2%) Query: 28 GNVIRVWLGSKLIVFLVDADDI-EIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86 G+++RV LG+ + A+ I E+ + +K + +P G+GL ++G R Sbjct: 40 GDLVRVNLGTMPMYVATSAELIHEVTVRQARSFEKGRFFDRLRPLAGDGLATANGEVHRK 99 Query: 87 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLET 143 HR++I P FH + + + N+ + + + G+ ++ M+ ++ L T Sbjct: 100 HRRLIQPMFHPGRITMYAETMSSNALALADSWTA--GQEVEMEQAMAQFAIETLATT 154 >UniRef50_Q7QCC3 Cluster: ENSANGP00000012179; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000012179 - Anopheles gambiae str. PEST Length = 504 Score = 109 bits (262), Expect = 2e-22 Identities = 62/234 (26%), Positives = 116/234 (49%), Gaps = 9/234 (3%) Query: 270 KKRLAFLDLMIES--SQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327 +K F+D +++ + SD EI + + T++ G++T+A + LL +H + Sbjct: 275 RKPQIFIDQLMKMPLTDPSARHFSDEEISDHIYTMIVAGNETSATQLAHTCLLLAMHPHI 334 Query: 328 QARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387 Q + Y+E+ + D+ T ++ YLE V+ E++RL P P++ R+ ++ + Sbjct: 335 QTKAYEEVAGLVFSPDQEITIELMKDLHYLECVLKEAMRLMPVAPIVGRQSRAEIVLD-- 392 Query: 388 NYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446 + IP G+ + + LHR+ + + F P FL + RH Y+++PFS GPR C+ Sbjct: 393 GHRIPQGSVFLFHFYALHRRKDVWGPTADEFEPGRFLADG--GRHPYAHLPFSGGPRGCI 450 Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500 G +YA RN+ ++++ ++ + Q I L A F V R+R Sbjct: 451 GYRYAMMSLKTLLAQLLRNYELMTDLRYEDIRYQYQISLNLA--FPHAVRLRRR 502 Score = 71.7 bits (168), Expect = 4e-11 Identities = 45/182 (24%), Positives = 96/182 (52%), Gaps = 7/182 (3%) Query: 36 GSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTF 95 GS+L + L + ++ +L K Y+ + L GLL + W+ HRK + TF Sbjct: 75 GSQLAIGLTHPELVQKVLTHPDCQAKPDLYKVVR--LPNGLLAAKYDVWKVHRKTLNSTF 132 Query: 96 HINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGISRKTQD 153 + IL+SFV IFN + +V +L + G ++ +Y+S T++++ T++G K + Sbjct: 133 NARILESFVPIFNDCTQRLVGRLDRYARSGDRCNILEYISACTLEMISRTSLG--GKVLE 190 Query: 154 ESGFDYAMAVMKMC-DIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNK 212 G + +A +++ I R + ++ + +++ T+ ++++ + + I T+K+I+ K Sbjct: 191 REGAEQFIANLEVALKTIGVRIFNIFLHIDFIYQFTALYRKEMRAINICQQFTSKIIQAK 250 Query: 213 KE 214 +E Sbjct: 251 RE 252 >UniRef50_Q93VK5 Cluster: At1g31800/68069_m00159; n=12; Magnoliophyta|Rep: At1g31800/68069_m00159 - Arabidopsis thaliana (Mouse-ear cress) Length = 595 Score = 109 bits (261), Expect = 2e-22 Identities = 64/215 (29%), Positives = 104/215 (48%), Gaps = 9/215 (4%) Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349 +S ++++++ T++ GH+T+AA ++ LL V A++ +E+ + GD R T Sbjct: 362 VSSKQLRDDLMTMLIAGHETSAAVLTWTFYLLTTEPSVVAKLQEEVDSVIGD--RFPTIQ 419 Query: 350 DTLEMKYLERVILESLRLYPPVPV-IARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQP 408 D ++KY RV+ ESLRLYP PV I R ++ D+ Y I G + I + LHR P Sbjct: 420 DMKKLKYTTRVMNESLRLYPQPPVLIRRSIDNDI---LGEYPIKRGEDIFISVWNLHRSP 476 Query: 409 KYYKDPEVFNPDNFL---PENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRN 465 ++ D E FNP+ + P + +SY+PF GPR C+G +A R Sbjct: 477 LHWDDAEKFNPERWPLDGPNPNETNQNFSYLPFGGGPRKCIGDMFASFENVVAIAMLIRR 536 Query: 466 FRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500 F K+ + EG ++ V R + Sbjct: 537 FNFQIAPGAPPVKMTTGATIHTTEGLKLTVTKRTK 571 Score = 49.2 bits (112), Expect = 3e-04 Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Query: 26 TFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHI-DKATEYRFFKPWLGEGLLISSGPKW 84 T+G + R+ G K + + D + IL + K +G+GL+ + G W Sbjct: 138 TYGGIFRLTFGPKSFLIVSDPSIAKHILKDNAKAYSKGILAEILDFVMGKGLIPADGEIW 197 Query: 85 RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDIL 140 R R+ I P H + + + +F + S+ + +KL + G+ ++ S T+DI+ Sbjct: 198 RRRRRAIVPALHQKYVAAMISLFGEASDRLCQKLDAAALKGEEVEMESLFSRLTLDII 255 >UniRef50_Q2Y711 Cluster: Cytochrome P450; n=1; Nitrosospira multiformis ATCC 25196|Rep: Cytochrome P450 - Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) Length = 448 Score = 107 bits (258), Expect = 5e-22 Identities = 87/318 (27%), Positives = 151/318 (47%), Gaps = 22/318 (6%) Query: 194 QTKLLGIIHGLTNKVIKNKK-ETYLENKAKGIIPPTLEEFTHHSGEILANN------AKT 246 Q L G + LT +VI T + +K + I P +LE ++ +AN T Sbjct: 140 QINLSGEMMRLTLEVITQTMFSTSVLDKIERIAP-SLEILLRYAARTIANPLTLPVYVPT 198 Query: 247 LSDTVFK---GYRDDLDFN--DENDVGEKKRLAFLDLMIESSQNGTN-KISDHEIKEEVD 300 ++ FK G DD+ + D+ + LD++++ + + K++D ++++EV Sbjct: 199 PANRKFKQALGIIDDVIYGIIDQRRAAPSDQNDLLDMLLKVRDDDSGEKMTDRQVRDEVI 258 Query: 301 TIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERV 360 TI GH+TTA S+ L LL H V R+ +EL ++ + D ++ Y V Sbjct: 259 TIFSAGHETTANLLSWTLYLLVRHPGVLTRLREELDRVL--QGKIPNAEDLQQLVYTRAV 316 Query: 361 ILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPD 420 + ES+RL PP + RK+++D + Y + AG + F LH ++ PE F+P+ Sbjct: 317 LSESMRLRPPASFLLRKVSKDTEVD--GYFLKAGKLAIFSIFNLHHHADFWPQPEQFDPE 374 Query: 421 NFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQ 480 FL +QNR YS+IPF G R C+G +A ++ + + KE +++ Sbjct: 375 RFL--LSQNRR-YSFIPFGTGERICIGSHFALMESQLLLCMIIQHC-DLQLLDSKEVEME 430 Query: 481 GDIILKRAEGFQMKVEPR 498 I L+ G +++ R Sbjct: 431 MAITLRPKGGIPVRINWR 448 >UniRef50_Q9NB69 Cluster: Cytochrome P450 monooxygenase; n=2; Tribolium castaneum|Rep: Cytochrome P450 monooxygenase - Tribolium castaneum (Red flour beetle) Length = 126 Score = 107 bits (258), Expect = 5e-22 Identities = 51/122 (41%), Positives = 73/122 (59%), Gaps = 1/122 (0%) Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374 +F L +L H VQ + E+ + GD+ + + D E+KY+ERVI E LRLYP V I Sbjct: 6 NFALMVLANHPTVQEEIVQEMKDVLGDTKKKPVYNDLQELKYMERVIKEVLRLYPSVHYI 65 Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434 +R+L D+ ++T Y + GT + + + LH P Y +PE F+PD FLPEN RH Y+ Sbjct: 66 SRELGEDM-VTTTGYKLRKGTILQLHIYDLHYNPVIYPEPEKFDPDRFLPENCDKRHPYA 124 Query: 435 YI 436 YI Sbjct: 125 YI 126 >UniRef50_A6WEH8 Cluster: Cytochrome P450; n=1; Kineococcus radiotolerans SRS30216|Rep: Cytochrome P450 - Kineococcus radiotolerans SRS30216 Length = 429 Score = 107 bits (257), Expect = 7e-22 Identities = 61/162 (37%), Positives = 90/162 (55%), Gaps = 6/162 (3%) Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349 + D ++++E+ T + GH+T A+ ++ L LL V ARV+ EL G R + Sbjct: 224 MDDRQVRDELVTFVVAGHETVASSLTWTLDLLARAPSVLARVHAELAGALGG--REPGWD 281 Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409 D ++ L V+ ESLRLYPP V+ R+ D ++ +PAGT V++ T+ LHR P Sbjct: 282 DLGKLPLLRAVVDESLRLYPPAWVVTRQALADDVVA--GVAVPAGTLVIVCTWGLHRDPA 339 Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 ++ PE F PD FL + SY+PF AGPR C+GR A Sbjct: 340 LWEAPEEFRPDRFL--DAPRPAAGSYVPFGAGPRLCIGRDLA 379 Score = 38.3 bits (85), Expect = 0.47 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 2/71 (2%) Query: 28 GNVIRVWLGSKLIVFLVDADDIEIILNSHVH-IDKAT-EYRFFKPWLGEGLLISSGPKWR 85 G V + L ++ L D D + +L + KAT +Y G GLL G W+ Sbjct: 24 GPVAAIPLPRTPVLVLADPDGVRRVLVENARGYGKATIQYSALATVTGPGLLAGDGEVWK 83 Query: 86 SHRKMIAPTFH 96 HR+ + P FH Sbjct: 84 QHRRTVQPAFH 94 >UniRef50_A7T1A2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 523 Score = 107 bits (257), Expect = 7e-22 Identities = 57/181 (31%), Positives = 100/181 (55%), Gaps = 3/181 (1%) Query: 272 RLAFLDLMIES-SQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330 R F+DLM+ + + +G+ K+SD EI + T + GH+T++ S L ++ +VQ R Sbjct: 297 RKDFVDLMLSAVNPDGSRKLSDPEIIAQSVTFLLAGHETSSNTLSATAYYLALNPEVQER 356 Query: 331 VYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYV 390 + E+ + + +++YL+ V+ E LR++PP I R+ + I+ Sbjct: 357 LRLEIRMAAETNSEKSPQELANDLEYLDCVVNEVLRIHPPAHTINRECAQACVIN--GIT 414 Query: 391 IPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKY 450 IPAG V I + LH P + +P+ F+P+ F ++RH + +IPF AGPR+C+G ++ Sbjct: 415 IPAGMDVTIPIYSLHHDPDAWPEPDKFDPERFRGPAKESRHPFQFIPFGAGPRNCIGMRF 474 Query: 451 A 451 A Sbjct: 475 A 475 >UniRef50_UPI0000E48EAF Cluster: PREDICTED: similar to cytochrome P450 CYP3A24; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cytochrome P450 CYP3A24 - Strongylocentrotus purpuratus Length = 412 Score = 107 bits (256), Expect = 9e-22 Identities = 48/172 (27%), Positives = 91/172 (52%), Gaps = 3/172 (1%) Query: 280 IESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIF 339 ++ + ++++ E+ + G++TT ++L LL H DVQ ++ +E+ + Sbjct: 195 LQKKSSSKIRLNESEVISQALIFFLAGYETTNTTCGYMLYLLATHPDVQDKLVNEIDDVA 254 Query: 340 GDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVI 399 +++ + +M YLE++ E+ R+YPP + R N I+ + +P G + I Sbjct: 255 PEAE-DVGYQSISKMPYLEQIFCETERIYPPALMTDRVCNEPFDIN--GFTVPKGMRIFI 311 Query: 400 GTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 F +H P + DPE ++PD F EN + H +++PF GPR+CVG ++A Sbjct: 312 PIFTIHHDPNLWPDPETYDPDRFSKENREKHHPCAWMPFGTGPRNCVGMRFA 363 >UniRef50_UPI0000D5745C Cluster: PREDICTED: similar to Probable cytochrome P450 28a5 (CYPXXVIIIA5); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Probable cytochrome P450 28a5 (CYPXXVIIIA5) - Tribolium castaneum Length = 740 Score = 107 bits (256), Expect = 9e-22 Identities = 58/194 (29%), Positives = 102/194 (52%), Gaps = 5/194 (2%) Query: 278 LMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELY 336 L I S TN+ +D ++ +G +T++ SFVL L I+ DVQ+++ E+ Sbjct: 270 LHIISQLKKTNQDFTDVDVTAHAAGFFADGSETSSIVMSFVLFQLSINPDVQSKLRAEVT 329 Query: 337 QIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN----YVIP 392 + F +++ + ++ YLE VI E+LR+ PP+ + + + T + K VI Sbjct: 330 EAFNNNNNNMPYEVVQDLPYLEAVIQETLRIQPPIHSLQKLCTKSFTWTLKETNKPLVIE 389 Query: 393 AGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 452 GT ++I T L P++++DPE F P+ FL EN +N +++PF GPR+C+G+++ Sbjct: 390 EGTPIIIPTHALQSDPQHFEDPESFQPERFLGENRENIKKCTHMPFGEGPRACLGQRFGL 449 Query: 453 XXXXXXXXXXXRNF 466 +NF Sbjct: 450 LQIKVGLAYIVKNF 463 >UniRef50_Q3EBT7 Cluster: Uncharacterized protein At2g26170.1; n=7; core eudicotyledons|Rep: Uncharacterized protein At2g26170.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 522 Score = 107 bits (256), Expect = 9e-22 Identities = 77/232 (33%), Positives = 116/232 (50%), Gaps = 12/232 (5%) Query: 275 FLDLMI---ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARV 331 FL L++ ES N + I + G TTA S VL L+ H DV+ R+ Sbjct: 294 FLSLILKARESDPFAKNIFTSDYISAVTYEHLLAGSATTAFTLSSVLYLVSGHLDVEKRL 353 Query: 332 YDELYQIFGDSDRPATFADTL-EMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYV 390 E+ FG+ D T D + YL++VI E++R Y P++AR+ ++V I Y+ Sbjct: 354 LQEI-DGFGNRDLIPTAHDLQHKFPYLDQVIKEAMRFYMVSPLVARETAKEVEIG--GYL 410 Query: 391 IPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP--ENTQNRHYYSYIPFSAGPRSCVGR 448 +P GT V + +L + PK + +PE F P+ F P E ++RH Y++IPF GPR+CVG+ Sbjct: 411 LPKGTWVWLALGVLAKDPKNFPEPEKFKPERFDPNGEEEKHRHPYAFIPFGIGPRACVGQ 470 Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGD--IILKRAEGFQMKVEPR 498 ++A RN+ E E LQ D IIL G +++ R Sbjct: 471 RFALQEIKLTLLHLYRNY-IFRHSLEMEIPLQLDYGIILSFKNGVKLRTIKR 521 >UniRef50_Q29AT3 Cluster: GA11819-PA; n=6; Diptera|Rep: GA11819-PA - Drosophila pseudoobscura (Fruit fly) Length = 513 Score = 107 bits (256), Expect = 9e-22 Identities = 61/214 (28%), Positives = 110/214 (51%), Gaps = 5/214 (2%) Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349 IS I + G +TT + ++FVL L + ++ R+ E+ + +D T+ Sbjct: 303 ISLESITAQAFIFYIAGQETTGSTAAFVLFELAQYPELLERLQTEVDETLAKNDGHITYD 362 Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409 +M++L+ + ESLR YP +P++ R+ +D T+ ++VIP GT VVI + +H + Sbjct: 363 ALQKMEFLDLCVQESLRKYPGLPMLNRECTQDYTVPDTDHVIPKGTPVVISLYGIHHDAE 422 Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRT- 468 Y+ +PE ++PD + EN +N +++PF GPR C+ ++ +NF Sbjct: 423 YFPEPETYDPDRYSEEN-RNFSPTAFMPFGEGPRICIAQRMGLLNAKLAIINVLKNFNVE 481 Query: 469 ISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRVP 502 + + EF+ G +L + G +KV KR+P Sbjct: 482 VMSKRQLEFENSGIALLPK-NG--VKVRLSKRLP 512 >UniRef50_Q9VG82 Cluster: Probable cytochrome P450 9f2; n=26; Endopterygota|Rep: Probable cytochrome P450 9f2 - Drosophila melanogaster (Fruit fly) Length = 516 Score = 107 bits (256), Expect = 9e-22 Identities = 54/180 (30%), Positives = 96/180 (53%), Gaps = 3/180 (1%) Query: 291 SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD-RPATFA 349 SD +I + F G +T+A F L +QDVQ R+Y+E+ Q+ D + + T+ Sbjct: 303 SDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYE 362 Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVT--ISTKNYVIPAGTTVVIGTFMLHRQ 407 + MKYL++V+ E LR +P + R+ N+D+T + + + G + + T HR Sbjct: 363 AIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRD 422 Query: 408 PKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467 PKY+++P F+P+ F EN ++ ++Y PF G R+C+G ++A +++R Sbjct: 423 PKYFENPMKFDPERFSDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYR 482 Score = 36.7 bits (81), Expect = 1.4 Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Query: 73 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT----FDV 128 G L +W+ R ++P F + ++ + NQ + V+ LK + + D+ Sbjct: 123 GSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDM 182 Query: 129 HDYMSGTTVDILLETAMGI 147 DY + T D++ TA G+ Sbjct: 183 KDYCTRFTNDVIASTAFGL 201 >UniRef50_Q27664 Cluster: Cytochrome P450 6B2; n=46; Obtectomera|Rep: Cytochrome P450 6B2 - Helicoverpa armigera (Cotton bollworm) (Heliothis armigera) Length = 504 Score = 107 bits (256), Expect = 9e-22 Identities = 69/241 (28%), Positives = 117/241 (48%), Gaps = 14/241 (5%) Query: 275 FLDLMIESSQNGT-------NKISDHEIKEEV---DTIMF--EGHDTTAAGSSFVLCLLG 322 F+DL++E Q G N +S EI E V +F G++T+A +++ L Sbjct: 263 FMDLILELRQMGEITSNKYGNNMSTLEITESVMCAQAFVFYIAGYETSATTMAYLTYQLA 322 Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382 ++ D+Q ++ E+ + + T+ +MKYL +V E+LR+Y V + RK RD Sbjct: 323 LNPDIQNKLIAEIDEAIKANGGKVTYDTVKDMKYLNKVFDETLRMYSIVEPLQRKAIRDY 382 Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442 + + VI T V+I +H PKYY +P+ FNP+ F E RH +Y+PF G Sbjct: 383 KLPGTDVVIEKDTVVLISPRGIHYDPKYYDNPKQFNPERFFAEEVGKRHPCAYLPFGLGQ 442 Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQG-DIILKRAEGFQMKVEPRKR 500 R+C+G ++ FR S+ ++ +++ I+ G ++ + PRK Sbjct: 443 RNCIGMRFGRLQSLLCITKLLSKFRLEPSKNTDRNLQVEPYRFIIGPKGGIRLNIVPRKD 502 Query: 501 V 501 V Sbjct: 503 V 503 Score = 48.0 bits (109), Expect = 6e-04 Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 2/124 (1%) Query: 30 VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89 VI ++ + + + D + I+ I+ + F K LG+ L + G WR+ R Sbjct: 71 VIGIYRMTSPCLLVRDLEVIKHIMIKDFEVFSDRGLEFSKEGLGQNLFHADGDTWRTLRN 130 Query: 90 MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGI 147 P F LK+ + N+ ++N ++ + E K F++H + T+ + A G+ Sbjct: 131 RFTPIFTSGKLKNMFYLMNEGADNFIDHVSKECEKHQEFEIHTLLQTYTMSTISSCAFGV 190 Query: 148 SRKT 151 S T Sbjct: 191 SYDT 194 >UniRef50_UPI00015B60B4 Cluster: PREDICTED: similar to cytochrome P450; n=3; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 533 Score = 106 bits (255), Expect = 1e-21 Identities = 60/189 (31%), Positives = 99/189 (52%), Gaps = 2/189 (1%) Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322 D+ + E K L D ++ + KIS E + G +TT++ ++ L L Sbjct: 285 DKGSLDEDKDLKQKDNNNSANGSALGKISLSEAIGQAFIFYLAGFETTSSTITYCLYELA 344 Query: 323 IHQDVQARVYDELYQIFGDSDRPATFAD-TLEMKYLERVILESLRLYPPVPVIARKLNRD 381 ++ ++Q +V E+ + F D T+ + +MKYL V LE+LR +P +P + R+ D Sbjct: 345 LNPEIQEKVQAEIDE-FSKRDGGITYEIMSNDMKYLHMVFLETLRKHPSIPFLNRECIED 403 Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441 I N+ I GT ++I +HR P + DPE F+P F EN +R Y+Y+PF G Sbjct: 404 CDIPNTNFRIEKGTKLLICMNAMHRDPDIFPDPEKFDPFRFTKENIASRQPYTYLPFGDG 463 Query: 442 PRSCVGRKY 450 PR+C+G ++ Sbjct: 464 PRACIGIRF 472 >UniRef50_UPI0000E473D8 Cluster: PREDICTED: hypothetical protein; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 507 Score = 106 bits (255), Expect = 1e-21 Identities = 58/178 (32%), Positives = 94/178 (52%), Gaps = 5/178 (2%) Query: 276 LDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDEL 335 L L I + G + +E T+ G +TT+ +F + LG H DV ++ E+ Sbjct: 286 LILDIANDLEGDKDFGMENMLDEFVTLFIAGQETTSNLLAFTILQLGRHPDVAKKLQAEV 345 Query: 336 YQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGT 395 ++ G + D +++Y+ RV+ E+LRLY PV R V + IPA Sbjct: 346 DEVLGQK-HTIQYEDLAKLEYMMRVLKETLRLYSPVGGTTRLTAHPVKYN--GITIPAKA 402 Query: 396 TVVIGTFMLHRQPKYYKDPEVFNPDNFLP--ENTQNRHYYSYIPFSAGPRSCVGRKYA 451 TV + ++++ R +Y+ DP +FNPD F P + + RH Y+Y PFS G RSC+G+++A Sbjct: 403 TVTVMSYVMSRMEEYFDDPLLFNPDRFKPSEDGSLPRHLYAYFPFSMGQRSCIGQQFA 460 Score = 39.5 bits (88), Expect = 0.20 Identities = 34/147 (23%), Positives = 61/147 (41%), Gaps = 11/147 (7%) Query: 42 FLVDADDI--EIILNSHVHIDKATEYRFFKP-----WLGEGLLIS-SGPKWRSHRKMIAP 93 F A +I E++LNS HI Y F+ ++G GL+ KW R ++ P Sbjct: 92 FFASAPEIVKELLLNSR-HIKPQEIYHGFQKLYGERFMGHGLVSEVDHEKWFHRRAIMNP 150 Query: 94 TFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVH--DYMSGTTVDILLETAMGISRKT 151 F L S + +N S + +KLK + +V D ++ T+D++ + A + Sbjct: 151 AFRRKYLISLMEEYNSGSEALCQKLKEKADGKIEVPMLDELNKVTLDVIAKIAFSMDTNA 210 Query: 152 QDESGFDYAMAVMKMCDIIHQRHYKFW 178 + + A+ + H + W Sbjct: 211 IGDPDCPFPAAITAALQGLQSLHERPW 237 >UniRef50_UPI0000E46433 Cluster: PREDICTED: similar to Cytochrome P450, family 2, subfamily u, polypeptide 1; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Cytochrome P450, family 2, subfamily u, polypeptide 1 - Strongylocentrotus purpuratus Length = 487 Score = 106 bits (255), Expect = 1e-21 Identities = 59/224 (26%), Positives = 110/224 (49%), Gaps = 8/224 (3%) Query: 281 ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG 340 E G +++ E+ V +M G DTT+ + + ++ + D+Q +V++E+ + G Sbjct: 261 EDDDVGEDRLKTKEVWRLVYDLMLAGSDTTSNTLKWAVLVMAYYPDIQKKVHNEIDCVLG 320 Query: 341 DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIG 400 + R D M Y++ I+E LR+ P +P+ L + T+ + Y IP G ++ Sbjct: 321 E--RSPCLQDKKSMSYIQATIMEVLRVRPVLPLALEHLTSETTV-LRGYTIPKGAILIPN 377 Query: 401 TFMLHRQPKYYKDPEVFNPDNFLPENTQN--RHYYSYIPFSAGPRSCVGRKYAXXXXXXX 458 + H P+Y+ +PEVFNP FL E+ Q+ ++++PFS GPR C+G + A Sbjct: 378 VWSCHHNPEYWDNPEVFNPGRFLSEDNQSLGEEPHAFLPFSFGPRKCLGDQLAKNELFLI 437 Query: 459 XXXXXRNFR---TISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 + F + PE + ++ R +++++PRK Sbjct: 438 FAKIMQRFHIDFAPGDRPESFDEGFDKGLILRPNNMKVRLQPRK 481 >UniRef50_Q82QD5 Cluster: Putative cytochrome P450 / NADPH-ferrihemoprotein reductase; n=1; Streptomyces avermitilis|Rep: Putative cytochrome P450 / NADPH-ferrihemoprotein reductase - Streptomyces avermitilis Length = 1073 Score = 106 bits (255), Expect = 1e-21 Identities = 62/225 (27%), Positives = 117/225 (52%), Gaps = 5/225 (2%) Query: 276 LDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 L LM+E++ T K + D ++++V T + GH+TT+ SF L + + A+ Y E Sbjct: 243 LGLMLEATDPETGKGLDDDNVRDQVVTFLIAGHETTSGLLSFATYSLMRNPHILAQAYAE 302 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 + ++ D + ++M + R++ E+LRL+ P+P+I + D I Y + G Sbjct: 303 VDRLL-PGDTVPDYDTIMQMDVIPRILEETLRLWAPIPMIGKSPLEDTVIGGC-YGLKKG 360 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454 V I LH PK ++ PE F+ + +LPEN N H ++Y PF G R+C+GR++A Sbjct: 361 ARVNILEGPLHTHPKAWERPEEFDINRWLPENRVNHHPHAYKPFGNGVRACIGRQFALTE 420 Query: 455 XXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499 + F+ ++ + + ++ + + ++ GF++ V R+ Sbjct: 421 ARLALALVLQKFK-FADTDDYKMDVK-EALTRKPGGFELNVRARQ 463 >UniRef50_Q2J4I2 Cluster: Cytochrome P450; n=2; Frankia|Rep: Cytochrome P450 - Frankia sp. (strain CcI3) Length = 489 Score = 106 bits (255), Expect = 1e-21 Identities = 65/228 (28%), Positives = 115/228 (50%), Gaps = 15/228 (6%) Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 L L++ + T + D ++++E T++ GH+TTA ++ LLG +V A + E Sbjct: 258 LSLLLTARDADTGASMDDSQVRDEALTLLLAGHETTANALTWTFHLLGRDPEVLATLQAE 317 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394 L ++ G +R T D ++ Y VI E++RLYPPV + R L D ++ Y +PAG Sbjct: 318 LDRVLG--ERRPTIDDLPQLPYTNAVISEAMRLYPPVWAMGRHLVEDRDVA--GYRLPAG 373 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQN---------RHYYSYIPFSAGPRSC 445 +T+V +++HR +++ PE+F+P + +T + R ++Y PF AGPR C Sbjct: 374 STLVFSQWVVHRDERWWPRPELFDPIRWTGPDTADEPADAGPKMRPRFAYFPFGAGPRQC 433 Query: 446 VGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQM 493 +G +A R + + + +P Q + L+ +G M Sbjct: 434 IGNTFAITEGVLALAAIARRW-SFTPVPGLPVTPQPLVTLRPKDGLPM 480 Score = 40.3 bits (90), Expect = 0.12 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 72 LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDY 131 LG+GLL S+G R R+++ P FH + + F ++ + + G+ DVH Sbjct: 113 LGQGLLTSAGDTHRQQRRLLQPLFHKQRIAGYADAFAAIADKTADGWRD--GQRLDVHTE 170 Query: 132 MSGTTVDILLETAMGI 147 M+ T+ I+ T + Sbjct: 171 MTEMTLAIVARTLFDV 186 >UniRef50_Q1ZXL9 Cluster: Cytochrome P450 family protein; n=2; Dictyostelium discoideum|Rep: Cytochrome P450 family protein - Dictyostelium discoideum AX4 Length = 601 Score = 106 bits (255), Expect = 1e-21 Identities = 64/207 (30%), Positives = 106/207 (51%), Gaps = 17/207 (8%) Query: 288 NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ-----IFGDS 342 + + + +I ++T + GH+T+A +F+ LL H +VQ +Y+ L + I D+ Sbjct: 375 DNVKEKDIIGNINTFLLAGHETSANLLTFIFYLLSTHNNVQNDLYNHLIENQKKKINKDN 434 Query: 343 DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST--------KNYVIPAG 394 D +++L+ VI E+LRL+PP P+I R D + + N IP+ Sbjct: 435 KFTEEDEDYQSIEFLDWVIYETLRLFPPAPMIGRTSKNDDILKSGNNNNNNNNNISIPSE 494 Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLP-ENTQNRHYYSYIPFSAGPRSCVGRKYAXX 453 T ++I + +HR PK +KDP +FNP + EN NR +IPFS+G R CVG+K++ Sbjct: 495 TLILISVYAIHRDPKLWKDPNIFNPYRWKNIENINNRS--DFIPFSSGGRVCVGQKFSIV 552 Query: 454 XXXXXXXXXXRNFR-TISEIPEKEFKL 479 NF + + + K FK+ Sbjct: 553 EARIIISKLILNFELSFNNLKSKPFKI 579 >UniRef50_Q9V4U7 Cluster: Probable cytochrome P450 6a14; n=10; Schizophora|Rep: Probable cytochrome P450 6a14 - Drosophila melanogaster (Fruit fly) Length = 509 Score = 106 bits (255), Expect = 1e-21 Identities = 56/194 (28%), Positives = 99/194 (51%), Gaps = 3/194 (1%) Query: 306 GHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTL-EMKYLERVILES 364 G +T+++ S L L + D+Q R+ +E+ + + D D L +M YL++V+ E+ Sbjct: 314 GFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSET 373 Query: 365 LRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP 424 LR +P +P + R+ +D I + V+ G +I +H P+ Y +PE F+P F P Sbjct: 374 LRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDP 433 Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKL-QGD 482 E +NRH +Y+PF GPR+C+G ++ R F+ ++S + + Sbjct: 434 EEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKS 493 Query: 483 IILKRAEGFQMKVE 496 +L +G +KVE Sbjct: 494 FLLTTNDGIYLKVE 507 >UniRef50_UPI0000DB6D9C Cluster: PREDICTED: similar to Cytochrome P450 6a2 (CYPVIA2) (P450-B1); n=1; Apis mellifera|Rep: PREDICTED: similar to Cytochrome P450 6a2 (CYPVIA2) (P450-B1) - Apis mellifera Length = 427 Score = 106 bits (254), Expect = 2e-21 Identities = 58/180 (32%), Positives = 91/180 (50%), Gaps = 4/180 (2%) Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334 F+ LMIE Q G KI + + + +G +T++ +F+ C L IHQDVQ ++ E Sbjct: 200 FIQLMIEMEQTG-EKIDEEIVAAHAVSFYLDGVETSSVTLNFIGCQLAIHQDVQEKLRKE 258 Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK---NYVI 391 + TF +M Y+ +VI ES R + + + + + + NY Sbjct: 259 VRSTLEKHGGVLTFEALKDMTYMNQVISESQRYFSALGFLGKICTDEFELQGSDGLNYRA 318 Query: 392 PAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451 GT ++I LH+ PKY+ +PE+F+P+ F EN Q ++IPF GPR CVG + A Sbjct: 319 KPGTELLIPICGLHKDPKYWDNPEIFDPERFSDENKQRIEKMAFIPFGEGPRICVGMRMA 378 >UniRef50_UPI0000D56516 Cluster: PREDICTED: similar to Probable cytochrome P450 6a20 (CYPVIA20); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Probable cytochrome P450 6a20 (CYPVIA20) - Tribolium castaneum Length = 442 Score = 106 bits (254), Expect = 2e-21 Identities = 56/204 (27%), Positives = 97/204 (47%) Query: 244 AKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIM 303 AK+ D R+ ++F ++ + L L + + + S E+ + Sbjct: 239 AKSAGDFFINIVRNTVEFREKTNTIRNDFLQLLINLKNDESDDWGQFSIEEVAAQCFIFF 298 Query: 304 FEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILE 363 G +T+A SF L + + V ++ DE+ ++ + EM YL +V+ E Sbjct: 299 LAGFETSATTMSFALYEIAANPHVYEQIMDEMRRVLDKYNGEMCHDAIKEMTYLGQVVDE 358 Query: 364 SLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFL 423 +LR++ P ++R +D + N V+ G V+I +H P++Y +PE F P+ F Sbjct: 359 TLRIHSPAYAVSRTCTQDYHVPETNIVLKKGFQVLIPIRGIHSDPEFYPEPEKFKPERFH 418 Query: 424 PENTQNRHYYSYIPFSAGPRSCVG 447 P+N QN YSY+PF GPR C+G Sbjct: 419 PDNRQNIEPYSYLPFGEGPRICIG 442 Score = 36.3 bits (80), Expect = 1.9 Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Query: 76 LLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMS 133 LL +G KW+ R + PTF +K IF + + L+ ++ +FDV + S Sbjct: 119 LLSLNGEKWKRLRSKLTPTFTAGKIKMVFKIFVECGKIIEHTLEHHAQNRTSFDVKEMFS 178 Query: 134 GTTVDILLETAMGI 147 + D+++ A G+ Sbjct: 179 SYSTDVIVNCAFGV 192 >UniRef50_Q0LK65 Cluster: Cytochrome P450; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Cytochrome P450 - Herpetosiphon aurantiacus ATCC 23779 Length = 454 Score = 106 bits (254), Expect = 2e-21 Identities = 63/205 (30%), Positives = 101/205 (49%), Gaps = 7/205 (3%) Query: 295 IKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEM 354 +++E T+ F GH+TTA SF+ L + DV R+ E+ + GD+ T ++ Sbjct: 256 LRDEAITVFFAGHETTARTLSFLWYALANNPDVAERMQAEIDSVLGDA--APTLDHLKQL 313 Query: 355 KYLERVILESLRLYPPVPVIARK-LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKD 413 Y +VI E+LRLYP P+ AR + D K +P G+ + I ++ HR P ++ Sbjct: 314 PYTLQVIKETLRLYPAAPMYARDAVASDEFAGIK---VPVGSRMTIMPYLTHRHPDFWDK 370 Query: 414 PEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIP 473 P F+PD +LPE RH ++Y PF+AG R C+G ++ R+F + +P Sbjct: 371 PLRFDPDRWLPEREALRHPFAYHPFAAGQRICIGNNFSLFESHVVVAMLARHF-ALRTVP 429 Query: 474 EKEFKLQGDIILKRAEGFQMKVEPR 498 ++ D L G M + R Sbjct: 430 NHTPQVWMDGTLGSRNGLPMFITQR 454 Score = 49.2 bits (112), Expect = 3e-04 Identities = 32/125 (25%), Positives = 64/125 (51%), Gaps = 4/125 (3%) Query: 27 FGNVIRVWLGSKLIVFLVDADDIEIIL--NSHVHIDKATEYRFFKPWLGEGLLISSGPKW 84 +G++ + LGSK + +V D + ++ + KA+ K LG+GL+ S+G W Sbjct: 39 YGDLAHLQLGSKDMFLVVHPDHVRRVMVEQRDTYSKKASYEGVRKLLLGDGLVASTGSLW 98 Query: 85 RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK--LKSEVGKTFDVHDYMSGTTVDILLE 142 R RK++AP F +++++ I ++ E+ ++ G+ D+ MS T I+L+ Sbjct: 99 RRQRKLMAPFFTPRAIETYLPIIVEDGAWFRERWSAAAKQGEPLDILTEMSVLTASIILK 158 Query: 143 TAMGI 147 + + Sbjct: 159 SMFSL 163 >UniRef50_A1HDJ4 Cluster: Cytochrome P450; n=4; Burkholderiaceae|Rep: Cytochrome P450 - Ralstonia pickettii 12J Length = 1079 Score = 106 bits (254), Expect = 2e-21 Identities = 64/209 (30%), Positives = 103/209 (49%), Gaps = 4/209 (1%) Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349 + D I+ +V T + GH+TT+ +F L +L H V A+ Y E+ ++ D +A Sbjct: 267 LDDTNIRFQVITFLIAGHETTSGLLTFALYMLLRHPAVLAQAYAEVDRVL-PGDTVPQYA 325 Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409 ++ +ERV+ E+LRL+P P D I + Y I VV LHR P Sbjct: 326 HLAQLDVIERVLKETLRLWPTAPSFGVAPYEDTRIGGR-YAIRKDQRVVTVLLALHRDPA 384 Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTI 469 + PE F+ D FLPEN H ++Y PF G R+C+GR++A + F + Sbjct: 385 VWDRPEAFDIDRFLPENEAKLHPHAYKPFGNGERACIGRQFALTEAKLALAVILQRF-AL 443 Query: 470 SEIPEKEFKLQGDIILKRAEGFQMKVEPR 498 S+ + F ++ + LK +GF+++ R Sbjct: 444 SDPYDYGFHIKETLTLK-PDGFRLRARLR 471 >UniRef50_Q5W1K8 Cluster: Cytochrome P450 CYP6AX1 protein; n=2; Hemiptera|Rep: Cytochrome P450 CYP6AX1 protein - Nilaparvata lugens (Brown planthopper) Length = 514 Score = 106 bits (254), Expect = 2e-21 Identities = 59/199 (29%), Positives = 101/199 (50%), Gaps = 3/199 (1%) Query: 255 YRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMF--EGHDTTAA 312 YR+D + + L +D +E N + + + +T +F G +TTA Sbjct: 265 YREDNKVERNDFIQILMNLKKIDENMEIDPNNESHVILDDKLLAANTFIFFIAGFETTAT 324 Query: 313 GSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVP 372 +F + L ++Q++Q ++ E+ F + + T +M YL+RVI E+LR YP Sbjct: 325 TLTFSMYELAVNQEIQDKLRQEVQTTF-EKYGAINYDSTKDMDYLDRVISETLRKYPIAG 383 Query: 373 VIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHY 432 + R+ + + + G VVI + +H PKYY DP+ F+P+ F PEN ++R Sbjct: 384 SLIRRCTKAWQVPGAKGKLEVGDRVVIPVYPIHHDPKYYPDPQKFDPERFTPENKRSRPP 443 Query: 433 YSYIPFSAGPRSCVGRKYA 451 +Y+PF GPR C+G ++A Sbjct: 444 CTYMPFGDGPRICIGARFA 462 Score = 40.3 bits (90), Expect = 0.12 Identities = 29/119 (24%), Positives = 55/119 (46%), Gaps = 5/119 (4%) Query: 34 WLGSKLIVFLVDADDI--EIILNSHVHI-DKATEYRFFKPWLGEGLLISSGPKWRSHRKM 90 WL ++ + +V ++ +I++ VH D+ T L LL +G +W++ R+ Sbjct: 81 WLANRSPLLMVKDPELIQQILVKDFVHFYDRGTTVDMKLDPLNANLLNMTGQRWKALRQK 140 Query: 91 IAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETAMGI 147 + P F LK FN+ +++ + KS + DV + MS D++ A G+ Sbjct: 141 LTPAFSSGKLKLMSPQFNECVDDLCGLIDEKSNKKELIDVQESMSKLATDVIGSCAFGL 199 >UniRef50_Q16FQ1 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 505 Score = 106 bits (254), Expect = 2e-21 Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 4/168 (2%) Query: 280 IESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIF 339 +E+S N + K++ E+ + G +T+++ SF L L + +VQ +V E+ + Sbjct: 288 VETSTN-SKKLTIGEVAAQAHVFFLAGFETSSSTMSFCLYELAKNPEVQRKVQSEIDSVT 346 Query: 340 GDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVI 399 D T+ EM+YLE I E+LR YPPVPV+ R+ +D + + I GT V++ Sbjct: 347 ALHDGKLTYDSINEMRYLECCIDETLRKYPPVPVLNRECTKDYKVPDSDITIEKGTAVIL 406 Query: 400 GTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447 +H P+YY DP F P+ FL + + + Y PF GPR C+G Sbjct: 407 QISAMHHDPQYYPDPLRFVPERFLDPDMKGK---PYAPFGDGPRICIG 451 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.320 0.137 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 563,526,749 Number of Sequences: 1657284 Number of extensions: 24165219 Number of successful extensions: 64211 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 1285 Number of HSP's successfully gapped in prelim test: 1008 Number of HSP's that attempted gapping in prelim test: 58611 Number of HSP's gapped (non-prelim): 3387 length of query: 507 length of database: 575,637,011 effective HSP length: 104 effective length of query: 403 effective length of database: 403,279,475 effective search space: 162521628425 effective search space used: 162521628425 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.8 bits) S2: 75 (34.3 bits)
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