SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001004-TA|BGIBMGA001004-PA|IPR001128|Cytochrome P450,
IPR000923|Blue (type 1) copper domain, IPR002401|E-class P450, group I
         (507 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9VYY4 Cluster: Cytochrome P450 4g15; n=8; Neoptera|Rep...   605   e-171
UniRef50_Q9V3S0 Cluster: Cytochrome P450 4g1; n=62; Protostomia|...   515   e-145
UniRef50_Q967Y5 Cluster: Cytochrome P450 CYP4G13v2; n=4; Neopter...   496   e-139
UniRef50_A0A8M5 Cluster: Cytochrome P450 4 family; n=1; Daphnia ...   363   4e-99
UniRef50_Q9VA27 Cluster: Cytochrome P450 4c3; n=15; Coelomata|Re...   363   8e-99
UniRef50_Q170T4 Cluster: Cytochrome P450; n=5; Endopterygota|Rep...   318   2e-85
UniRef50_Q27589 Cluster: Cytochrome P450 4d2; n=8; Acalyptratae|...   299   1e-79
UniRef50_UPI00015B569E Cluster: PREDICTED: similar to cytochrome...   299   1e-79
UniRef50_UPI00015B5D09 Cluster: PREDICTED: similar to cytochrome...   297   3e-79
UniRef50_Q6VAB7 Cluster: Cytochrome P450 CYP4AB2; n=6; Apocrita|...   297   3e-79
UniRef50_A0MNW4 Cluster: Cyp4M9; n=20; Obtectomera|Rep: Cyp4M9 -...   288   3e-76
UniRef50_Q9VS79 Cluster: Cytochrome P450 4d8; n=6; Schizophora|R...   278   2e-73
UniRef50_Q170T0 Cluster: Cytochrome P450; n=12; Culicidae|Rep: C...   277   5e-73
UniRef50_UPI0000D55ACE Cluster: PREDICTED: similar to Cytochrome...   275   2e-72
UniRef50_UPI00015B604A Cluster: PREDICTED: similar to cytochrome...   272   2e-71
UniRef50_A7SWY9 Cluster: Predicted protein; n=3; Nematostella ve...   272   2e-71
UniRef50_Q9Y1T8 Cluster: Cytochrome P450 4W1; n=3; Arthropoda|Re...   256   1e-66
UniRef50_Q9NB96 Cluster: P450 CYP319A1; n=2; Parasitiformes|Rep:...   255   2e-66
UniRef50_Q9N574 Cluster: Cytochrome p450 family protein 31A3; n=...   254   5e-66
UniRef50_UPI00015B4DC8 Cluster: PREDICTED: similar to corpora al...   248   3e-64
UniRef50_Q4R1I7 Cluster: Cytochrome P450; n=1; Papilio xuthus|Re...   239   2e-61
UniRef50_O45120 Cluster: Family 4 cytochrome P450; n=2; Coptoter...   237   4e-61
UniRef50_Q170S9 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cy...   234   5e-60
UniRef50_Q16ML8 Cluster: Cytochrome P450; n=3; Culicidae|Rep: Cy...   232   1e-59
UniRef50_UPI00015B5014 Cluster: PREDICTED: similar to cytochrome...   229   1e-58
UniRef50_UPI00015B561A Cluster: PREDICTED: similar to cytochrome...   221   3e-56
UniRef50_A0JMQ6 Cluster: Cytochrome P450, family 4, subfamily V,...   215   2e-54
UniRef50_Q6ZWL3 Cluster: Cytochrome P450 4V2; n=83; Coelomata|Re...   214   5e-54
UniRef50_UPI0000D566B3 Cluster: PREDICTED: similar to Cytochrome...   212   2e-53
UniRef50_UPI00015B569D Cluster: PREDICTED: similar to cytochrome...   210   7e-53
UniRef50_Q964T1 Cluster: Cytochrome P450 4c21; n=1; Blattella ge...   203   1e-50
UniRef50_Q7YSZ3 Cluster: P450 enzyme precursor; n=1; Rhodnius pr...   202   2e-50
UniRef50_Q9VVN6 Cluster: Probable cytochrome P450 312a1; n=2; So...   202   2e-50
UniRef50_UPI0000E46807 Cluster: PREDICTED: similar to cytochrome...   201   3e-50
UniRef50_Q9NGQ5 Cluster: Insecticide resistance-associated cytoc...   196   1e-48
UniRef50_A6Y7S1 Cluster: Female neotenic-specific protein 4; n=1...   196   2e-48
UniRef50_Q695H3 Cluster: Pheromone-degrading enzyme; n=2; Phyllo...   195   2e-48
UniRef50_O76478 Cluster: Corpora allata cytochrome P450; n=2; Ne...   195   2e-48
UniRef50_A1BPS2 Cluster: CYP4BF1; n=2; Ips paraconfusus|Rep: CYP...   195   3e-48
UniRef50_UPI0000E46144 Cluster: PREDICTED: similar to ENSANGP000...   192   2e-47
UniRef50_Q27472 Cluster: Cytochrome p450 family protein 32A1; n=...   192   2e-47
UniRef50_UPI0000D55952 Cluster: PREDICTED: similar to Cytochrome...   191   4e-47
UniRef50_UPI00015B560A Cluster: PREDICTED: similar to cytochrome...   188   3e-46
UniRef50_UPI0000D56049 Cluster: PREDICTED: similar to Probable c...   188   3e-46
UniRef50_Q178T9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep...   188   4e-46
UniRef50_Q9U1R5 Cluster: Putative uncharacterized protein cyp-42...   186   1e-45
UniRef50_Q7YXL0 Cluster: Cytochrome P450 monooxygenase; n=2; Tri...   183   1e-44
UniRef50_Q8ISJ7 Cluster: Cytochrome P450 CYP4L4; n=4; Noctuidae|...   182   3e-44
UniRef50_UPI00015B61D7 Cluster: PREDICTED: similar to Cytochrome...   181   5e-44
UniRef50_UPI0000D56462 Cluster: PREDICTED: similar to cytochrome...   180   6e-44
UniRef50_Q8ISJ8 Cluster: Cytochrome P450 CYP4S4; n=3; Noctuidae|...   180   8e-44
UniRef50_O17851 Cluster: Putative uncharacterized protein cyp-37...   178   3e-43
UniRef50_A1BPS5 Cluster: CYP4BJ1; n=1; Ips paraconfusus|Rep: CYP...   178   3e-43
UniRef50_Q9N4Q5 Cluster: Cytochrome p450 family protein 32B1; n=...   176   1e-42
UniRef50_Q9VXY0 Cluster: Probable cytochrome P450 4s3; n=5; Acal...   175   2e-42
UniRef50_A1BPS4 Cluster: CYP4BH1; n=1; Ips paraconfusus|Rep: CYP...   174   4e-42
UniRef50_UPI0000D55B03 Cluster: PREDICTED: similar to Cytochrome...   173   7e-42
UniRef50_Q9VMS9 Cluster: Probable cytochrome P450 4ac1; n=5; Sop...   169   1e-40
UniRef50_Q16IS6 Cluster: Cytochrome P450; n=12; Culicidae|Rep: C...   167   8e-40
UniRef50_UPI00015B5E04 Cluster: PREDICTED: similar to CG8302-PA;...   166   1e-39
UniRef50_Q16I47 Cluster: Cytochrome P450; n=7; Culicidae|Rep: Cy...   166   1e-39
UniRef50_Q170T3 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   165   2e-39
UniRef50_Q17PE3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep...   164   6e-39
UniRef50_Q16P39 Cluster: Cytochrome P450; n=7; Aedes aegypti|Rep...   164   6e-39
UniRef50_Q9V7G5 Cluster: Probable cytochrome P450 4aa1; n=5; Dip...   164   6e-39
UniRef50_Q9XVA6 Cluster: Putative uncharacterized protein cyp-37...   163   1e-38
UniRef50_Q9V558 Cluster: Cytochrome P450 4p1; n=5; Sophophora|Re...   163   1e-38
UniRef50_Q9N525 Cluster: Cytochrome p450 family protein 29A3; n=...   163   1e-38
UniRef50_Q16E69 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   162   2e-38
UniRef50_A1BPR9 Cluster: CYP4BD1; n=1; Ips paraconfusus|Rep: CYP...   160   9e-38
UniRef50_UPI0000D5646A Cluster: PREDICTED: similar to CYtochrome...   159   1e-37
UniRef50_Q27606 Cluster: Cytochrome P450 4e2; n=11; Diptera|Rep:...   157   5e-37
UniRef50_A1BPS3 Cluster: CYP4BG1; n=1; Ips paraconfusus|Rep: CYP...   157   9e-37
UniRef50_P33269 Cluster: Cytochrome P450 4d1; n=11; Diptera|Rep:...   157   9e-37
UniRef50_O46054 Cluster: Cytochrome P450 4ae1; n=1; Drosophila m...   157   9e-37
UniRef50_Q9VLZ7 Cluster: Probable cytochrome P450 4d21; n=5; Sop...   156   1e-36
UniRef50_UPI00015B5723 Cluster: PREDICTED: similar to cytochrome...   155   2e-36
UniRef50_Q16L55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   155   3e-36
UniRef50_P13584 Cluster: Cytochrome P450 4B1; n=32; Euteleostomi...   155   3e-36
UniRef50_UPI00015B5196 Cluster: PREDICTED: similar to cytochrome...   154   6e-36
UniRef50_Q179B7 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   154   6e-36
UniRef50_UPI0000F2BA18 Cluster: PREDICTED: similar to Cytochrome...   153   1e-35
UniRef50_UPI0000D9991B Cluster: PREDICTED: similar to cytochrome...   152   2e-35
UniRef50_UPI0000D56470 Cluster: PREDICTED: similar to Cytochrome...   150   7e-35
UniRef50_Q6TGT4 Cluster: Thromboxane A synthase 1; n=6; cellular...   148   3e-34
UniRef50_Q6PW73 Cluster: Cytochrome P450 CYP4AT1; n=1; Capitella...   147   5e-34
UniRef50_Q02928 Cluster: Cytochrome P450 4A11 precursor; n=114; ...   146   9e-34
UniRef50_Q9VG40 Cluster: Probable cytochrome P450 313a4; n=3; So...   145   2e-33
UniRef50_Q4U3Y4 Cluster: CYP325C2; n=4; Anopheles gambiae|Rep: C...   144   4e-33
UniRef50_Q16L50 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   144   4e-33
UniRef50_Q8N118 Cluster: Cytochrome P450 4X1; n=12; Mammalia|Rep...   144   4e-33
UniRef50_Q6NT55 Cluster: Cytochrome P450 4F22; n=127; Deuterosto...   144   5e-33
UniRef50_Q6SPQ6 Cluster: CYP4BB1; n=2; Protostomia|Rep: CYP4BB1 ...   144   6e-33
UniRef50_Q8K4D6 Cluster: Cytochrome P450 4X1; n=15; Eutheria|Rep...   143   8e-33
UniRef50_Q5XM61 Cluster: Cytochrome P450; n=9; Pancrustacea|Rep:...   142   1e-32
UniRef50_Q5V5P9 Cluster: Cytochrome P450; n=3; Halobacteriaceae|...   142   1e-32
UniRef50_Q8WQN5 Cluster: Cytochrome P450 CYP4H14; n=22; Endopter...   142   3e-32
UniRef50_Q176V3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep...   141   5e-32
UniRef50_UPI0000D56469 Cluster: PREDICTED: similar to cytochrome...   140   6e-32
UniRef50_A6GGL1 Cluster: Cytochrome P450 family protein; n=1; Pl...   140   8e-32
UniRef50_Q17DZ0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   140   1e-31
UniRef50_A1BPR7 Cluster: CYP4AY1; n=2; Ips paraconfusus|Rep: CYP...   139   1e-31
UniRef50_Q9KFA6 Cluster: Cytochrome P450 hydroxylase; n=1; Bacil...   139   2e-31
UniRef50_UPI0001555B83 Cluster: PREDICTED: similar to cytochrome...   138   2e-31
UniRef50_UPI0000D56468 Cluster: PREDICTED: similar to Cytochrome...   138   2e-31
UniRef50_Q3IR83 Cluster: Unspecific monooxygenase; n=1; Natronom...   138   3e-31
UniRef50_Q82D73 Cluster: Putative cytochrome P450; n=2; Streptom...   136   1e-30
UniRef50_UPI0000D55FA3 Cluster: PREDICTED: similar to Cytochrome...   136   2e-30
UniRef50_Q6SPQ5 Cluster: CYP342A1; n=1; Nereis virens|Rep: CYP34...   136   2e-30
UniRef50_Q4U3Y5 Cluster: CYP325D1; n=1; Anopheles gambiae|Rep: C...   134   7e-30
UniRef50_Q4STK8 Cluster: Chromosome undetermined SCAF14158, whol...   133   9e-30
UniRef50_A7SJV6 Cluster: Predicted protein; n=3; Nematostella ve...   133   9e-30
UniRef50_Q98T91 Cluster: Cytochrome P450 3A40; n=16; Euteleostom...   133   1e-29
UniRef50_Q6PH32 Cluster: Cytochrome P450, family 4; n=7; Clupeoc...   132   2e-29
UniRef50_Q3L917 Cluster: Cytochrome P450; n=1; Rhodococcus eryth...   132   2e-29
UniRef50_P05184 Cluster: Cytochrome P450 3A3; n=159; Euteleostom...   132   3e-29
UniRef50_A7D7T8 Cluster: Cytochrome P450; n=1; Halorubrum lacusp...   131   5e-29
UniRef50_Q8WQN9 Cluster: Cytochrome P450 CYP4J5; n=22; Endoptery...   130   6e-29
UniRef50_Q095M8 Cluster: Cytochrome P450 4A5; n=1; Stigmatella a...   130   8e-29
UniRef50_A7DM29 Cluster: Cytochrome P450; n=2; Methylobacterium ...   130   1e-28
UniRef50_Q3I414 Cluster: Cytochrome P450; n=18; Cucujiformia|Rep...   129   1e-28
UniRef50_Q177R7 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep...   128   5e-28
UniRef50_Q495Y1 Cluster: CYP3A43 protein; n=4; Homo sapiens|Rep:...   128   5e-28
UniRef50_Q8WQN1 Cluster: Cytochrome P450 CYP4H24; n=23; Culicida...   127   6e-28
UniRef50_Q8T632 Cluster: Cytochrome P450 CYP6P3; n=42; Diptera|R...   127   6e-28
UniRef50_Q16TD6 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep...   126   1e-27
UniRef50_UPI0000D56467 Cluster: PREDICTED: similar to Cytochrome...   126   1e-27
UniRef50_Q06GC7 Cluster: Cytochrome P450; n=1; Rhodococcus sp. N...   126   1e-27
UniRef50_UPI000038CC01 Cluster: COG2124: Cytochrome P450; n=1; N...   126   2e-27
UniRef50_Q964R1 Cluster: Cytochrome P450 6j1; n=1; Blattella ger...   126   2e-27
UniRef50_Q0IG08 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   125   2e-27
UniRef50_UPI00015B4AC4 Cluster: PREDICTED: similar to cytochrome...   124   4e-27
UniRef50_A3RK60 Cluster: Cytochrome P450; n=2; Liposcelis bostry...   124   6e-27
UniRef50_Q9PVE8 Cluster: Cytochrome P450 3A30; n=4; Percomorpha|...   124   6e-27
UniRef50_Q9VGB3 Cluster: Probable cytochrome P450 313a3; n=2; Dr...   124   7e-27
UniRef50_Q3E385 Cluster: Cytochrome P450; n=3; Chloroflexus|Rep:...   123   1e-26
UniRef50_Q17PE0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   123   1e-26
UniRef50_A7RNE6 Cluster: Predicted protein; n=1; Nematostella ve...   123   1e-26
UniRef50_UPI0000D555E9 Cluster: PREDICTED: similar to Cytochrome...   123   1e-26
UniRef50_Q5KR92 Cluster: Cytochrome P450; n=1; Hodotermopsis sjo...   123   1e-26
UniRef50_UPI00015B480C Cluster: PREDICTED: similar to cytochrome...   122   2e-26
UniRef50_UPI0000D5558E Cluster: PREDICTED: similar to Cytochrome...   122   2e-26
UniRef50_Q964R0 Cluster: Cytochrome P450 6k1; n=1; Blattella ger...   122   2e-26
UniRef50_UPI0000DB7C31 Cluster: PREDICTED: similar to Probable c...   122   2e-26
UniRef50_Q629N7 Cluster: Cytochrome P450-related protein; n=24; ...   122   2e-26
UniRef50_Q27691 Cluster: Cytochrome P450; n=2; Musca domestica|R...   122   2e-26
UniRef50_A7SRX7 Cluster: Predicted protein; n=2; Nematostella ve...   122   2e-26
UniRef50_Q5TXA2 Cluster: ENSANGP00000026709; n=2; Anopheles gamb...   122   3e-26
UniRef50_A7SCY4 Cluster: Predicted protein; n=1; Nematostella ve...   122   3e-26
UniRef50_Q70AR5 Cluster: Putative cytochrome P450; n=1; Streptom...   121   4e-26
UniRef50_Q1D9Z9 Cluster: Cytochrome P450 family protein; n=1; My...   121   4e-26
UniRef50_Q25176 Cluster: Cytochrome P-450; n=24; Ditrysia|Rep: C...   121   4e-26
UniRef50_A7HP72 Cluster: Cytochrome P450; n=1; Parvibaculum lava...   121   5e-26
UniRef50_UPI0000E48D2E Cluster: PREDICTED: similar to MGC64404 p...   120   7e-26
UniRef50_Q1IM54 Cluster: Cytochrome P450; n=1; Acidobacteria bac...   120   7e-26
UniRef50_A5P357 Cluster: Cytochrome P450; n=1; Methylobacterium ...   120   7e-26
UniRef50_Q964T2 Cluster: Cytochrome P450 9e2; n=2; Blattaria|Rep...   120   7e-26
UniRef50_UPI0000E4657A Cluster: PREDICTED: similar to cytochrome...   120   9e-26
UniRef50_O76345 Cluster: Cytochrome P450; n=1; Homarus americanu...   120   9e-26
UniRef50_UPI00015B5073 Cluster: PREDICTED: similar to cytochrome...   120   1e-25
UniRef50_Q9VYQ7 Cluster: Probable cytochrome P450 311a1; n=2; Dr...   120   1e-25
UniRef50_UPI0000D576F7 Cluster: PREDICTED: similar to Cytochrome...   119   2e-25
UniRef50_Q825N1 Cluster: Cytochrome P450 hydroxylase; n=6; Actin...   119   2e-25
UniRef50_A4X8D8 Cluster: Cytochrome P450; n=5; Actinomycetales|R...   119   2e-25
UniRef50_A1UDQ6 Cluster: Cytochrome P450; n=10; Mycobacterium|Re...   119   2e-25
UniRef50_Q8UF31 Cluster: Cytochrome P450; n=1; Agrobacterium tum...   119   2e-25
UniRef50_Q89R90 Cluster: Blr2882 protein; n=4; Bacteria|Rep: Blr...   119   2e-25
UniRef50_UPI0000D56428 Cluster: PREDICTED: similar to Cytochrome...   118   3e-25
UniRef50_O76107 Cluster: Cytochrome P450; n=2; Culicini|Rep: Cyt...   118   3e-25
UniRef50_A7SXR0 Cluster: Predicted protein; n=5; Nematostella ve...   118   3e-25
UniRef50_UPI0000F21E21 Cluster: PREDICTED: similar to cytochrome...   118   4e-25
UniRef50_Q1DEH2 Cluster: Cytochrome P450 family protein; n=1; My...   118   4e-25
UniRef50_Q9V4T3 Cluster: Probable cytochrome P450 4ad1; n=2; Sop...   118   4e-25
UniRef50_Q9PWP0 Cluster: Cytochrome P450; n=2; Dicentrarchus lab...   118   5e-25
UniRef50_A1WAC7 Cluster: Cytochrome P450; n=1; Acidovorax sp. JS...   118   5e-25
UniRef50_A7LFI0 Cluster: Cytochrome P450; n=3; Tribolium castane...   118   5e-25
UniRef50_A0NGH0 Cluster: ENSANGP00000031109; n=7; Culicidae|Rep:...   118   5e-25
UniRef50_UPI000065CBAF Cluster: Thromboxane-A synthase (EC 5.3.9...   117   6e-25
UniRef50_UPI00015B5352 Cluster: PREDICTED: similar to cytochrome...   117   8e-25
UniRef50_A7DLL5 Cluster: Cytochrome P450; n=1; Methylobacterium ...   117   8e-25
UniRef50_UPI00005A2E9B Cluster: PREDICTED: similar to cytochrome...   116   1e-24
UniRef50_Q0LLJ2 Cluster: Cytochrome P450; n=1; Herpetosiphon aur...   116   1e-24
UniRef50_Q5W1K7 Cluster: Cytochrome P450 CYP6AY1 protein; n=3; H...   116   1e-24
UniRef50_Q309A5 Cluster: Cytochrome P450 monooxygenase; n=22; Ap...   116   1e-24
UniRef50_Q27594 Cluster: Cytochrome P450 6a9; n=15; Schizophora|...   116   1e-24
UniRef50_Q8T624 Cluster: Cytochrome P450 CYP9L1 protein; n=6; Ce...   116   1e-24
UniRef50_Q0IEL1 Cluster: Cytochrome P450; n=6; Culicini|Rep: Cyt...   116   1e-24
UniRef50_O16156 Cluster: Cytochrome P450 30; n=1; Mercenaria mer...   116   1e-24
UniRef50_Q9VGB4 Cluster: Probable cytochrome P450 313a2; n=2; Dr...   116   1e-24
UniRef50_Q5U3Q3 Cluster: Cytochrome P450, family 3, subfamily c,...   116   2e-24
UniRef50_Q56JT9 Cluster: Cytochrome P450 monooxygenase; n=10; En...   116   2e-24
UniRef50_UPI0000D56564 Cluster: PREDICTED: similar to Probable c...   115   3e-24
UniRef50_A7RQ80 Cluster: Predicted protein; n=5; Nematostella ve...   115   3e-24
UniRef50_UPI0000D56E82 Cluster: PREDICTED: similar to Cytochrome...   114   4e-24
UniRef50_Q178V0 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cy...   114   4e-24
UniRef50_A7RSL1 Cluster: Predicted protein; n=2; Nematostella ve...   114   4e-24
UniRef50_Q8WQM9 Cluster: Cytochrome P450 CYP6M1; n=7; Culicidae|...   114   6e-24
UniRef50_Q8MZK0 Cluster: Cytochrome P450; n=6; Culicidae|Rep: Cy...   114   6e-24
UniRef50_Q695H1 Cluster: Antennae-rich cytochrome P450; n=3; Pol...   114   6e-24
UniRef50_UPI00015B4FBC Cluster: PREDICTED: similar to cytochrome...   113   8e-24
UniRef50_A0NQ01 Cluster: Cytochrome P450; n=1; Stappia aggregata...   113   8e-24
UniRef50_Q9GQM9 Cluster: Cytochrome P450 6l1; n=1; Blattella ger...   113   8e-24
UniRef50_Q9VGB5 Cluster: Probable cytochrome P450 313a5; n=2; Dr...   113   8e-24
UniRef50_Q0LL77 Cluster: Cytochrome P450; n=1; Herpetosiphon aur...   113   1e-23
UniRef50_Q8MTC8 Cluster: Cytochrome P450 monooxygenase CYP321A1;...   113   1e-23
UniRef50_UPI0000D576F6 Cluster: PREDICTED: similar to Probable c...   113   1e-23
UniRef50_A1ZWE3 Cluster: Cytochrome P450 family protein; n=1; Mi...   113   1e-23
UniRef50_Q9BID0 Cluster: Cytochrome P450; n=27; Culicidae|Rep: C...   113   1e-23
UniRef50_P33270 Cluster: Cytochrome P450 6a2; n=10; Diptera|Rep:...   113   1e-23
UniRef50_UPI0000E473EA Cluster: PREDICTED: hypothetical protein;...   112   2e-23
UniRef50_Q70AR8 Cluster: Putative cytochrome P450; n=1; Streptom...   112   2e-23
UniRef50_UPI0000DB7562 Cluster: PREDICTED: similar to Probable c...   111   3e-23
UniRef50_Q0LHR9 Cluster: Cytochrome P450; n=1; Herpetosiphon aur...   111   4e-23
UniRef50_A7RMN2 Cluster: Predicted protein; n=1; Nematostella ve...   111   4e-23
UniRef50_UPI0000D577ED Cluster: PREDICTED: similar to Cytochrome...   111   6e-23
UniRef50_Q0LFI0 Cluster: Cytochrome P450; n=1; Herpetosiphon aur...   111   6e-23
UniRef50_A5FJE6 Cluster: Cytochrome P450; n=1; Flavobacterium jo...   111   6e-23
UniRef50_Q6PW74 Cluster: Cytochrome P450 CYP331A1; n=1; Capitell...   110   7e-23
UniRef50_UPI0000D5650B Cluster: PREDICTED: similar to Cytochrome...   110   1e-22
UniRef50_A2XB72 Cluster: Putative uncharacterized protein; n=2; ...   109   1e-22
UniRef50_Q234S0 Cluster: Cytochrome P450 family protein; n=2; Te...   109   1e-22
UniRef50_Q179B9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep...   109   1e-22
UniRef50_Q0UKV8 Cluster: Putative uncharacterized protein; n=1; ...   109   1e-22
UniRef50_A1DAX0 Cluster: Cytochrome P450; n=5; Trichocomaceae|Re...   109   1e-22
UniRef50_Q70AR1 Cluster: Putative cytochrome P450; n=1; Streptom...   109   2e-22
UniRef50_Q7QCC3 Cluster: ENSANGP00000012179; n=1; Anopheles gamb...   109   2e-22
UniRef50_Q93VK5 Cluster: At1g31800/68069_m00159; n=12; Magnoliop...   109   2e-22
UniRef50_Q2Y711 Cluster: Cytochrome P450; n=1; Nitrosospira mult...   107   5e-22
UniRef50_Q9NB69 Cluster: Cytochrome P450 monooxygenase; n=2; Tri...   107   5e-22
UniRef50_A6WEH8 Cluster: Cytochrome P450; n=1; Kineococcus radio...   107   7e-22
UniRef50_A7T1A2 Cluster: Predicted protein; n=2; Nematostella ve...   107   7e-22
UniRef50_UPI0000E48EAF Cluster: PREDICTED: similar to cytochrome...   107   9e-22
UniRef50_UPI0000D5745C Cluster: PREDICTED: similar to Probable c...   107   9e-22
UniRef50_Q3EBT7 Cluster: Uncharacterized protein At2g26170.1; n=...   107   9e-22
UniRef50_Q29AT3 Cluster: GA11819-PA; n=6; Diptera|Rep: GA11819-P...   107   9e-22
UniRef50_Q9VG82 Cluster: Probable cytochrome P450 9f2; n=26; End...   107   9e-22
UniRef50_Q27664 Cluster: Cytochrome P450 6B2; n=46; Obtectomera|...   107   9e-22
UniRef50_UPI00015B60B4 Cluster: PREDICTED: similar to cytochrome...   106   1e-21
UniRef50_UPI0000E473D8 Cluster: PREDICTED: hypothetical protein;...   106   1e-21
UniRef50_UPI0000E46433 Cluster: PREDICTED: similar to Cytochrome...   106   1e-21
UniRef50_Q82QD5 Cluster: Putative cytochrome P450 / NADPH-ferrih...   106   1e-21
UniRef50_Q2J4I2 Cluster: Cytochrome P450; n=2; Frankia|Rep: Cyto...   106   1e-21
UniRef50_Q1ZXL9 Cluster: Cytochrome P450 family protein; n=2; Di...   106   1e-21
UniRef50_Q9V4U7 Cluster: Probable cytochrome P450 6a14; n=10; Sc...   106   1e-21
UniRef50_UPI0000DB6D9C Cluster: PREDICTED: similar to Cytochrome...   106   2e-21
UniRef50_UPI0000D56516 Cluster: PREDICTED: similar to Probable c...   106   2e-21
UniRef50_Q0LK65 Cluster: Cytochrome P450; n=1; Herpetosiphon aur...   106   2e-21
UniRef50_A1HDJ4 Cluster: Cytochrome P450; n=4; Burkholderiaceae|...   106   2e-21
UniRef50_Q5W1K8 Cluster: Cytochrome P450 CYP6AX1 protein; n=2; H...   106   2e-21
UniRef50_Q16FQ1 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep...   106   2e-21
UniRef50_Q4SQM7 Cluster: Chromosome 17 SCAF14532, whole genome s...   105   2e-21
UniRef50_A0YW07 Cluster: Cytochrome P450 hydroxylase; n=1; Lyngb...   105   2e-21
UniRef50_A0Y8J6 Cluster: Probable bifunctional P-450:NADPH-P450 ...   105   2e-21
UniRef50_A5YU13 Cluster: CYP97C3; n=1; Chlamydomonas reinhardtii...   105   2e-21
UniRef50_Q121J8 Cluster: Cytochrome P450; n=2; Comamonadaceae|Re...   105   3e-21
UniRef50_A3VL14 Cluster: Possible cytochrome P450 hydroxylase su...   105   3e-21
UniRef50_Q17BD6 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   105   3e-21
UniRef50_UPI0000E4963D Cluster: PREDICTED: similar to cytochrome...   105   4e-21
UniRef50_A5YU14 Cluster: CYP97A5; n=4; Chlorophyta|Rep: CYP97A5 ...   105   4e-21
UniRef50_Q7QH22 Cluster: ENSANGP00000012679; n=5; Cellia|Rep: EN...   105   4e-21
UniRef50_Q52S21 Cluster: Cytochrome P450; n=3; Plutella xylostel...   105   4e-21
UniRef50_Q00G65 Cluster: Midgut-specific cytochrome P450; n=2; I...   104   5e-21
UniRef50_P30608 Cluster: Cytochrome P450 52A6; n=19; Saccharomyc...   104   5e-21
UniRef50_UPI0000D577EE Cluster: PREDICTED: similar to Probable c...   104   6e-21
UniRef50_UPI0000D561ED Cluster: PREDICTED: similar to Probable c...   104   6e-21
UniRef50_A3RIC1 Cluster: Cytochrome P450; n=1; Bombyx mori|Rep: ...   104   6e-21
UniRef50_Q56VS2 Cluster: Cytochrome P450 monooxygenase pc-3; n=2...   104   6e-21
UniRef50_Q9V675 Cluster: Probable cytochrome P450 6g2; n=2; Soph...   104   6e-21
UniRef50_UPI00015A5D7D Cluster: hypothetical protein LOC10003739...   103   8e-21
UniRef50_Q39NW6 Cluster: Cytochrome P450; n=1; Burkholderia sp. ...   103   8e-21
UniRef50_Q8KUI0 Cluster: Cytochrome P450; n=1; Actinosynnema pre...   103   8e-21
UniRef50_A1W125 Cluster: Cytochrome P450 family protein; n=12; C...   103   8e-21
UniRef50_P82711 Cluster: Probable cytochrome P450 6a19; n=11; Dr...   103   8e-21
UniRef50_Q8T5C1 Cluster: Cytochrome P450 monooxygenase CYP6X1v1;...   103   1e-20
UniRef50_Q86GR1 Cluster: Cytochrome P450 CYPm3r5; n=12; Culicida...   103   1e-20
UniRef50_Q4Q2L1 Cluster: Cytochrome p450-like protein; n=4; Leis...   103   1e-20
UniRef50_Q3I417 Cluster: Cytochrome P450; n=4; Cucujiformia|Rep:...   103   1e-20
UniRef50_Q8NJK3 Cluster: Cytochrome P450 monooxygenase pc-2; n=7...   103   1e-20
UniRef50_P37122 Cluster: Cytochrome P450 76A2; n=10; Spermatophy...   103   1e-20
UniRef50_Q9V769 Cluster: Cytochrome P450 6a22; n=2; Sophophora|R...   103   1e-20
UniRef50_Q3E1G3 Cluster: Cytochrome P450; n=2; Chloroflexus|Rep:...   103   1e-20
UniRef50_Q4H2B4 Cluster: Cytochrome P450 monooxygenase; n=2; Bas...   103   1e-20
UniRef50_Q2GUJ4 Cluster: Putative uncharacterized protein; n=2; ...   103   1e-20
UniRef50_Q82IY3 Cluster: Pentalenene C13 hydroxylase; cytochrome...   102   2e-20
UniRef50_Q162V4 Cluster: Cytochrome P450 family protein, putativ...   102   2e-20
UniRef50_A6G220 Cluster: Cytochrome P450; n=1; Plesiocystis paci...   102   2e-20
UniRef50_A1ZZK3 Cluster: Cytochrome P450 4A10; n=1; Microscilla ...   102   2e-20
UniRef50_P98186 Cluster: Cytochrome P450; n=1; Rhipicephalus mic...   102   2e-20
UniRef50_A7SWV9 Cluster: Predicted protein; n=1; Nematostella ve...   102   2e-20
UniRef50_UPI0000D56CEB Cluster: PREDICTED: similar to Probable c...   102   3e-20
UniRef50_A3Q0Q7 Cluster: Cytochrome P450 precursor; n=3; Mycobac...   102   3e-20
UniRef50_A5BGU6 Cluster: Putative uncharacterized protein; n=1; ...   102   3e-20
UniRef50_Q174T2 Cluster: Cytochrome P450; n=13; Aedes aegypti|Re...   102   3e-20
UniRef50_A6FMY4 Cluster: Cytochrome P450; n=12; Rhodobacterales|...   101   3e-20
UniRef50_A1ZCF9 Cluster: Cytochrome P450, putative; n=1; Microsc...   101   3e-20
UniRef50_Q9ASR3 Cluster: At2g46960/F14M4.21; n=7; core eudicotyl...   101   3e-20
UniRef50_Q5XNT3 Cluster: Cytochrome P450; n=2; Anopheles gambiae...   101   3e-20
UniRef50_Q16F55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   101   3e-20
UniRef50_A7SKW0 Cluster: Predicted protein; n=6; Nematostella ve...   101   3e-20
UniRef50_Q7SY18 Cluster: Zgc:63602; n=2; Danio rerio|Rep: Zgc:63...   101   4e-20
UniRef50_Q9Y6A2 Cluster: Cytochrome P450 46A1; n=22; Amniota|Rep...   101   4e-20
UniRef50_Q9VHP4 Cluster: Probable cytochrome P450 313b1; n=2; So...   101   4e-20
UniRef50_A5NX46 Cluster: Cytochrome P450; n=2; Alphaproteobacter...   101   6e-20
UniRef50_Q27693 Cluster: Cytochrome P450; n=2; Musca domestica|R...   101   6e-20
UniRef50_UPI00015B60BE Cluster: PREDICTED: similar to cytochrome...   100   8e-20
UniRef50_UPI000038DD76 Cluster: COG2124: Cytochrome P450; n=1; N...   100   8e-20
UniRef50_Q9AXM6 Cluster: Taxane 10-beta-hydroxylase; n=16; Eukar...   100   8e-20
UniRef50_UPI00015B62A7 Cluster: PREDICTED: similar to cytochrome...   100   1e-19
UniRef50_UPI0000E48111 Cluster: PREDICTED: similar to cytochrome...   100   1e-19
UniRef50_UPI0000DB77A2 Cluster: PREDICTED: similar to Probable c...   100   1e-19
UniRef50_A4FHE9 Cluster: Bifunctional P-450:NADPH-P450 reductase...   100   1e-19
UniRef50_Q9LUD2 Cluster: Cytochrome P450; n=6; core eudicotyledo...   100   1e-19
UniRef50_Q0U771 Cluster: Putative uncharacterized protein; n=3; ...   100   1e-19
UniRef50_P13527 Cluster: Cytochrome P450 6A1; n=3; Musca domesti...   100   1e-19
UniRef50_UPI0000D56E81 Cluster: PREDICTED: similar to Probable c...    99   1e-19
UniRef50_Q1YFK2 Cluster: Cytochrome P450; n=1; Aurantimonas sp. ...    99   1e-19
UniRef50_Q11B49 Cluster: Cytochrome P450; n=8; Rhizobiales|Rep: ...    99   1e-19
UniRef50_Q0GK98 Cluster: Cytochrome P450 CYP3-like member 4; n=3...    99   1e-19
UniRef50_Q92045 Cluster: Cytochrome P450 11A1, mitochondrial pre...    99   1e-19
UniRef50_UPI00015B5C73 Cluster: PREDICTED: similar to cytochrome...   100   2e-19
UniRef50_Q2L6E2 Cluster: P450; n=1; Streptomyces sp. KO-3988|Rep...   100   2e-19
UniRef50_A7DAQ3 Cluster: Cytochrome P450; n=2; Methylobacterium ...   100   2e-19
UniRef50_A7T0U5 Cluster: Predicted protein; n=2; Nematostella ve...   100   2e-19
UniRef50_Q66JP5 Cluster: Cytochrome P450, family 2, subfamily j,...    99   2e-19
UniRef50_Q603T8 Cluster: Cytochrome P450 51; n=1; Methylococcus ...    99   2e-19
UniRef50_Q9SCP8 Cluster: Cytochrom P450-like protein; n=12; Magn...    99   2e-19
UniRef50_Q9LUC8 Cluster: Cytochrome P450; n=84; Magnoliophyta|Re...    99   2e-19
UniRef50_UPI0000E49A50 Cluster: PREDICTED: hypothetical protein;...    99   3e-19
UniRef50_UPI00003BFC2E Cluster: PREDICTED: similar to Probable c...    99   3e-19
UniRef50_Q05047 Cluster: Cytochrome P450 72A1; n=10; core eudico...    99   3e-19
UniRef50_Q6DHE1 Cluster: Zgc:109896 protein; n=20; Euteleostomi|...    98   4e-19
UniRef50_A6G0E4 Cluster: Cytochrome P450 51; n=1; Plesiocystis p...    98   4e-19
UniRef50_A5HKL8 Cluster: Cytochrome P450 CYP9A22; n=5; Ditrysia|...    98   4e-19
UniRef50_Q2TW05 Cluster: Cytochrome P450 CYP4/CYP19/CYP26 subfam...    98   4e-19
UniRef50_O74131 Cluster: Cytochrome P450 52; n=6; Yarrowia lipol...    98   4e-19
UniRef50_UPI0000D559EB Cluster: PREDICTED: similar to Probable c...    98   6e-19
UniRef50_UPI0000D9A6B6 Cluster: PREDICTED: similar to Cytochrome...    97   7e-19
UniRef50_Q0LJ67 Cluster: Cytochrome P450; n=2; cellular organism...    97   7e-19
UniRef50_Q2LAK7 Cluster: Cytochrome P450 monooxygenase CYP72A67;...    97   7e-19
UniRef50_Q16L53 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep...    97   7e-19
UniRef50_UPI00015B6122 Cluster: PREDICTED: similar to cytochrome...    97   1e-18
UniRef50_UPI00015B480D Cluster: PREDICTED: similar to cytochrome...    97   1e-18
UniRef50_UPI0000DB76BC Cluster: PREDICTED: similar to Probable c...    97   1e-18
UniRef50_UPI0000D561F4 Cluster: PREDICTED: similar to Cytochrome...    97   1e-18
UniRef50_A6FXD3 Cluster: Cytochrome P450 family protein; n=1; Pl...    97   1e-18
UniRef50_O48925 Cluster: CYP82C1p; n=5; core eudicotyledons|Rep:...    97   1e-18
UniRef50_Q8T631 Cluster: Cytochrome P450 CYP6Z1; n=20; Culicidae...    97   1e-18
UniRef50_Q3I415 Cluster: Cytochrome P450; n=1; Leptinotarsa dece...    97   1e-18
UniRef50_Q55AJ4 Cluster: Cytochrome P450 family protein; n=2; Di...    97   1e-18
UniRef50_Q16FW7 Cluster: Cytochrome P450; n=16; Culicidae|Rep: C...    97   1e-18
UniRef50_A5JM35 Cluster: Cytochrome P450 Cyp6AU1; n=1; Bombyx mo...    97   1e-18
UniRef50_Q59990 Cluster: Putative cytochrome P450 120; n=8; Cyan...    97   1e-18
UniRef50_P82712 Cluster: Probable cytochrome P450 12d1 proximal,...    97   1e-18
UniRef50_UPI00015B595F Cluster: PREDICTED: similar to cytochrome...    96   2e-18
UniRef50_A6G6Z8 Cluster: Cytochrome P450; n=1; Plesiocystis paci...    96   2e-18
UniRef50_Q069I9 Cluster: Gossypol-induced cytochrome P450; n=9; ...    96   2e-18
UniRef50_A7S334 Cluster: Predicted protein; n=3; Nematostella ve...    96   2e-18
UniRef50_Q2UI50 Cluster: Cytochrome P450 CYP4/CYP19/CYP26 subfam...    96   2e-18
UniRef50_Q5UXK0 Cluster: Cytochrome P450; n=1; Haloarcula marism...    96   2e-18
UniRef50_A6G8E6 Cluster: Cytochrome P450; n=1; Plesiocystis paci...    96   2e-18
UniRef50_A6CJ44 Cluster: Cytochrome P450 hydroxylase; n=1; Bacil...    96   2e-18
UniRef50_Q9ZW95 Cluster: F5A8.3 protein; n=1; Arabidopsis thalia...    96   2e-18
UniRef50_A7SF10 Cluster: Predicted protein; n=1; Nematostella ve...    96   2e-18
UniRef50_A2QLX8 Cluster: Contig An07c0010, complete genome; n=1;...    96   2e-18
UniRef50_O43174 Cluster: Cytochrome P450 26A1; n=40; Euteleostom...    96   2e-18
UniRef50_UPI0000E480BF Cluster: PREDICTED: similar to cytochrome...    95   3e-18
UniRef50_Q9GTL1 Cluster: Putative cytochrome P450 monooxigenase;...    95   3e-18
UniRef50_Q9V9L1 Cluster: Probable cytochrome P450 6w1; n=3; Dros...    95   3e-18
UniRef50_UPI0000E4A2FC Cluster: PREDICTED: hypothetical protein;...    95   4e-18
UniRef50_UPI0000E49151 Cluster: PREDICTED: similar to cytochrome...    95   4e-18
UniRef50_UPI0000D56E84 Cluster: PREDICTED: similar to Probable c...    95   4e-18
UniRef50_Q5KSN6 Cluster: Putative P450; n=1; Streptomyces sp. KO...    95   4e-18
UniRef50_A5NYU6 Cluster: Cytochrome P450; n=1; Methylobacterium ...    95   4e-18
UniRef50_Q9LUD1 Cluster: Cytochrome P450-like protein; n=1; Arab...    95   4e-18
UniRef50_A7PQ75 Cluster: Chromosome chr18 scaffold_24, whole gen...    95   4e-18
UniRef50_A1XEM0 Cluster: CYP82E8; n=22; Nicotiana|Rep: CYP82E8 -...    95   4e-18
UniRef50_Q6R7M4 Cluster: Cytochrome P450 CYP15A1; n=2; Neoptera|...    95   4e-18
UniRef50_Q174T6 Cluster: Cytochrome P450; n=6; Culicidae|Rep: Cy...    95   4e-18
UniRef50_UPI00015B6167 Cluster: PREDICTED: similar to cytochrome...    95   5e-18
UniRef50_Q7PIH2 Cluster: ENSANGP00000024048; n=1; Anopheles gamb...    95   5e-18
UniRef50_A7RPN7 Cluster: Predicted protein; n=1; Nematostella ve...    95   5e-18
UniRef50_P51589 Cluster: Cytochrome P450 2J2; n=55; Theria|Rep: ...    95   5e-18
UniRef50_UPI00015B46F7 Cluster: PREDICTED: similar to Cyp6g1; n=...    94   7e-18
UniRef50_A7U483 Cluster: Cytochrome P450 family 17 polypeptide 2...    94   7e-18
UniRef50_A7PEY9 Cluster: Chromosome chr11 scaffold_13, whole gen...    94   7e-18
UniRef50_Q5B6B3 Cluster: Cytochrome P450 52; n=5; Eurotiomycetid...    94   7e-18
UniRef50_P24557 Cluster: Thromboxane-A synthase; n=40; Tetrapoda...    94   7e-18
UniRef50_Q7Z449 Cluster: Cytochrome P450 2U1; n=25; Euteleostomi...    94   7e-18
UniRef50_Q6VVX0 Cluster: Cytochrome P450 2R1; n=28; cellular org...    94   7e-18
UniRef50_UPI00015B569B Cluster: PREDICTED: similar to cytochrome...    94   9e-18
UniRef50_Q6AX26 Cluster: MGC86342 protein; n=2; Xenopus|Rep: MGC...    94   9e-18
UniRef50_Q89VZ9 Cluster: Bll0894 protein; n=13; Alphaproteobacte...    94   9e-18
UniRef50_Q82IV2 Cluster: Cytochrome P450 hydroxylase; n=2; Strep...    94   9e-18
UniRef50_Q0S645 Cluster: Cytochrome P450 CYP136; n=4; Actinomyce...    94   9e-18
UniRef50_A4A9V8 Cluster: Cytochrome P450; n=4; Bacteria|Rep: Cyt...    94   9e-18
UniRef50_Q9FF18 Cluster: Cytochrome P450-like protein; n=9; Magn...    94   9e-18
UniRef50_Q2VPT6 Cluster: Cytochrome P450 CYP6P1; n=21; Neoptera|...    94   9e-18
UniRef50_UPI0000DB6FEA Cluster: PREDICTED: similar to Probable c...    93   1e-17
UniRef50_O81653 Cluster: Senescence-associated protein 3; n=1; H...    93   1e-17
UniRef50_Q8WQN0 Cluster: Cytochrome P450 CYP6S2; n=6; Culicidae|...    93   1e-17
UniRef50_Q6JEK3 Cluster: 14a demethylase; n=1; Strongylocentrotu...    93   1e-17
UniRef50_A1CS83 Cluster: NADPH cytochrome P450; n=1; Aspergillus...    93   1e-17
UniRef50_UPI0000E49F6F Cluster: PREDICTED: similar to cytochrome...    93   2e-17
UniRef50_Q9FL55 Cluster: Cytochrome P450-like protein; n=2; Arab...    93   2e-17
UniRef50_A3B3X2 Cluster: Putative uncharacterized protein; n=3; ...    93   2e-17
UniRef50_A1XEH2 Cluster: CYP82M1v1; n=5; Nicotiana tabacum|Rep: ...    93   2e-17
UniRef50_Q5XNU2 Cluster: Cytochrome P450; n=3; Culicidae|Rep: Cy...    93   2e-17
UniRef50_Q2HFV6 Cluster: Putative uncharacterized protein; n=1; ...    93   2e-17
UniRef50_Q0ASD0 Cluster: Cytochrome P450; n=1; Maricaulis maris ...    93   2e-17
UniRef50_Q9Y1L1 Cluster: Ecdysone 20 hydroxylase; n=1; Locusta m...    93   2e-17
UniRef50_Q86QN2 Cluster: Cytochrome P450 CYP12F1; n=15; Culicida...    93   2e-17
UniRef50_Q5XM71 Cluster: Cytochrome P450; n=2; Anopheles gambiae...    93   2e-17
UniRef50_A7RT69 Cluster: Predicted protein; n=1; Nematostella ve...    93   2e-17
UniRef50_Q9V6H1 Cluster: Probable cytochrome P450 9h1; n=3; Soph...    93   2e-17
UniRef50_Q9V676 Cluster: Probable cytochrome P450 6t3; n=3; Soph...    93   2e-17
UniRef50_P95099 Cluster: Putative cytochrome P450 136; n=15; Myc...    93   2e-17
UniRef50_UPI00015B513C Cluster: PREDICTED: similar to cytochrome...    92   3e-17
UniRef50_UPI000038CD69 Cluster: COG2124: Cytochrome P450; n=1; N...    92   3e-17
UniRef50_Q5Z0Q8 Cluster: Cytochrome P450 monooxygenase; n=6; Cor...    92   3e-17
UniRef50_A4BWJ8 Cluster: Cytochrome P450; n=6; Bacteroidetes|Rep...    92   3e-17
UniRef50_A2YMR4 Cluster: Putative uncharacterized protein; n=3; ...    92   3e-17
UniRef50_A6SJT4 Cluster: Putative uncharacterized protein; n=2; ...    92   3e-17
UniRef50_P05093 Cluster: Cytochrome P450 17A1; n=46; Amniota|Rep...    92   3e-17
UniRef50_UPI00015B4ED4 Cluster: PREDICTED: similar to cytochrome...    92   4e-17
UniRef50_UPI00003C05B8 Cluster: PREDICTED: similar to Probable c...    92   4e-17
UniRef50_Q9AVM3 Cluster: Cytochrome P450; n=7; BEP clade|Rep: Cy...    92   4e-17
UniRef50_A4QQR9 Cluster: Putative uncharacterized protein; n=6; ...    92   4e-17
UniRef50_Q964Q7 Cluster: Cytochrome P450 6d3; n=9; Schizophora|R...    92   4e-17
UniRef50_Q94EV6 Cluster: Cytochrome P450; n=19; Poaceae|Rep: Cyt...    91   5e-17
UniRef50_Q2UT03 Cluster: Cytochrome P450 52; n=6; Trichocomaceae...    91   5e-17
UniRef50_Q9VRI9 Cluster: Probable cytochrome P450 6t1; n=1; Dros...    91   5e-17
UniRef50_Q6PA33 Cluster: MGC68652 protein; n=9; Xenopus|Rep: MGC...    91   6e-17
UniRef50_Q4SI76 Cluster: Chromosome 5 SCAF14581, whole genome sh...    91   6e-17
UniRef50_Q9X7G9 Cluster: Cytochrome P450 hydroxylase; n=2; Myxoc...    91   6e-17
UniRef50_Q17GV0 Cluster: Cytochrome P450; n=4; Aedes aegypti|Rep...    91   6e-17
UniRef50_Q9P493 Cluster: Cytochrome P-450 cyp509A1; n=1; Cunning...    91   6e-17
UniRef50_P0A513 Cluster: Cytochrome P450 51; n=19; Corynebacteri...    91   6e-17
UniRef50_P33261 Cluster: Cytochrome P450 2C19 (EC 1.14.13.80) ((...    91   6e-17
UniRef50_UPI00015B5A0F Cluster: PREDICTED: similar to cytochrome...    91   8e-17
UniRef50_UPI0000D55B02 Cluster: PREDICTED: similar to Probable c...    91   8e-17
UniRef50_Q9RTN4 Cluster: Cytochrome P450; n=1; Deinococcus radio...    91   8e-17
UniRef50_Q6NCP8 Cluster: Possible cytochrome P450 hydroxylase su...    91   8e-17
UniRef50_Q26HX2 Cluster: Cytochrome P450 hydroxylase; n=1; Flavo...    91   8e-17
UniRef50_Q0DIA1 Cluster: Os05g0405500 protein; n=4; Oryza sativa...    91   8e-17
UniRef50_Q55W77 Cluster: Putative uncharacterized protein; n=2; ...    91   8e-17
UniRef50_Q9V674 Cluster: Cytochrome P450 6g1; n=16; Schizophora|...    91   8e-17
UniRef50_UPI0000F2BC00 Cluster: PREDICTED: similar to CYP2J4; n=...    90   1e-16
UniRef50_Q31NH2 Cluster: Cytochrome P450; n=2; Synechococcus elo...    90   1e-16
UniRef50_A4PBE8 Cluster: Cytochrome P450 enzyme; n=9; Magnolioph...    90   1e-16
UniRef50_A6S200 Cluster: Putative uncharacterized protein; n=1; ...    90   1e-16
UniRef50_A1C5L5 Cluster: Cytochrome P450 oxidoreductase, putativ...    90   1e-16
UniRef50_UPI0000E251E4 Cluster: PREDICTED: similar to cytochrome...    90   1e-16
UniRef50_Q2LAL2 Cluster: Cytochrome P450 monooxygenase CYP76O2; ...    90   1e-16
UniRef50_Q0E2P9 Cluster: Os02g0221900 protein; n=15; Magnoliophy...    90   1e-16
UniRef50_Q0CQY1 Cluster: Cytochrome P450 52; n=1; Aspergillus te...    90   1e-16
UniRef50_A2QVX7 Cluster: Remark: astaxanthin is a ketocarotenoid...    90   1e-16
UniRef50_P20853 Cluster: Cytochrome P450 2A7; n=156; Euteleostom...    90   1e-16
UniRef50_P48420 Cluster: Cytochrome P450 78A1; n=19; Spermatophy...    90   1e-16
UniRef50_UPI0000E47585 Cluster: PREDICTED: similar to cytochrome...    89   2e-16
UniRef50_UPI0000D56374 Cluster: PREDICTED: similar to Cytochrome...    89   2e-16
UniRef50_Q7SXE6 Cluster: LOC402831 protein; n=17; Euteleostomi|R...    89   2e-16
UniRef50_Q54SK0 Cluster: Cytochrome P450 family protein; n=1; Di...    89   2e-16
UniRef50_A1CIZ0 Cluster: Cytochrome P450; n=1; Aspergillus clava...    89   2e-16
UniRef50_Q96SQ9 Cluster: Cytochrome P450 2S1; n=12; Theria|Rep: ...    89   2e-16
UniRef50_P08683 Cluster: Cytochrome P450 2C11 (EC 1.14.14.1) (CY...    89   2e-16
UniRef50_UPI0000E4A8EA Cluster: PREDICTED: similar to GA15235-PA...    89   3e-16
UniRef50_UPI0000E49222 Cluster: PREDICTED: similar to CYP4BB1 is...    89   3e-16
UniRef50_A0GM07 Cluster: Cytochrome P450; n=1; Burkholderia phyt...    89   3e-16
UniRef50_A7S7K8 Cluster: Predicted protein; n=1; Nematostella ve...    89   3e-16
UniRef50_Q66ZJ5 Cluster: Cytochrome P450; n=5; Homo/Pan/Gorilla ...    89   3e-16
UniRef50_P29980 Cluster: Probable cytochrome P450 110; n=2; Nost...    89   3e-16
UniRef50_UPI0000E4A41F Cluster: PREDICTED: hypothetical protein;...    89   3e-16
UniRef50_UPI0000D6651A Cluster: PREDICTED: similar to Cytochrome...    89   3e-16
UniRef50_Q4UXF7 Cluster: Cytochrome P450 hydroxylase; n=2; Xanth...    89   3e-16
UniRef50_Q25AL2 Cluster: H0102C09.4 protein; n=7; Oryza sativa|R...    89   3e-16
UniRef50_A7R5U7 Cluster: Chromosome undetermined scaffold_1067, ...    89   3e-16
UniRef50_Q16FQ2 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...    89   3e-16
UniRef50_A0A8M4 Cluster: Cytochrome P450 314 family; n=1; Daphni...    89   3e-16
UniRef50_O13820 Cluster: C-22 sterol desaturase Erg5; n=11; Asco...    89   3e-16
UniRef50_A6RAM5 Cluster: Cytochrome P450 61; n=3; Pezizomycotina...    89   3e-16
UniRef50_O48927 Cluster: Cytochrome P450 78A3; n=7; core eudicot...    89   3e-16
UniRef50_Q42716 Cluster: Cytochrome P450 71A8; n=1; Mentha x pip...    89   3e-16
UniRef50_Q8YQS3 Cluster: Cytochrome P450; n=7; Cyanobacteria|Rep...    88   4e-16
UniRef50_Q9SZ46 Cluster: Cytochrome P450-like protein; n=11; cor...    88   4e-16
UniRef50_Q1PEI9 Cluster: Cytochrome P450 family protein; n=2; Ar...    88   4e-16
UniRef50_Q5XNT0 Cluster: Cytochrome P450; n=4; Culicidae|Rep: Cy...    88   4e-16
UniRef50_Q0P0N3 Cluster: Aromatase; n=4; Branchiostoma|Rep: Arom...    88   4e-16
UniRef50_Q0GBX4 Cluster: Cytochrome P450 CYP3-like member 1; n=1...    88   4e-16
UniRef50_A5JTS8 Cluster: Cytochrome P450; n=7; Ditrysia|Rep: Cyt...    88   4e-16
UniRef50_Q9SD85 Cluster: Flavonoid 3'-monooxygenase; n=66; Magno...    88   4e-16
UniRef50_UPI0000E4A420 Cluster: PREDICTED: similar to MGC140497 ...    88   6e-16
UniRef50_Q8YMU4 Cluster: Cytochrome P450; n=10; Cyanobacteria|Re...    88   6e-16
UniRef50_A6FYS5 Cluster: Possible cytochrome P450 hydroxylase su...    88   6e-16
UniRef50_Q9SML3 Cluster: Cytochrome P450 monooxygenase; n=1; Cic...    88   6e-16
UniRef50_Q9M4X2 Cluster: Putative cytochrome P450; n=3; Solanace...    88   6e-16
UniRef50_Q59I67 Cluster: Flavone synthase II; n=9; asterids|Rep:...    88   6e-16
UniRef50_Q0E4L3 Cluster: Os02g0113200 protein; n=5; Oryza sativa...    88   6e-16
UniRef50_A7PDZ0 Cluster: Chromosome chr11 scaffold_13, whole gen...    88   6e-16
UniRef50_Q7PIP7 Cluster: ENSANGP00000025243; n=6; Culicidae|Rep:...    88   6e-16
UniRef50_Q22Z86 Cluster: Cytochrome P450 family protein; n=1; Te...    88   6e-16

>UniRef50_Q9VYY4 Cluster: Cytochrome P450 4g15; n=8; Neoptera|Rep:
           Cytochrome P450 4g15 - Drosophila melanogaster (Fruit
           fly)
          Length = 574

 Score =  605 bits (1493), Expect = e-171
 Identities = 290/496 (58%), Positives = 370/496 (74%), Gaps = 26/496 (5%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86
           F ++ ++W+G KL+VF+ D  D+E++L+SHV+IDKA+EY+FFKPWLG+GLLIS+G KWRS
Sbjct: 79  FEHIAKMWIGPKLVVFIYDPRDVELLLSSHVYIDKASEYKFFKPWLGDGLLISTGQKWRS 138

Query: 87  HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMG 146
           HRK+IAPTFH+N+LKSF+ +FN+NS NVV KL++E G+TFD HDYMS  TV+ILLETAMG
Sbjct: 139 HRKLIAPTFHLNVLKSFIELFNENSRNVVRKLRAEDGRTFDCHDYMSEATVEILLETAMG 198

Query: 147 ISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTN 206
           +S+KTQD+SGF+YAMAVM+MCDI+H RH   ++R+E VF LT ++K+Q +LL IIHGLT 
Sbjct: 199 VSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTRYYKEQGRLLNIIHGLTT 258

Query: 207 KVIKNKKETY----------LENKAKGI------------IPPTL--EEFTHHSGEILAN 242
           KVI++KK  +           E KA  +             P T   +E      +  A+
Sbjct: 259 KVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTAGSDEKDREKDKEKAS 318

Query: 243 NAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTI 302
               LS     G +DDLD  D ND+GEKKRLAFLDLM+ES+QNG   I+D EIKE+VDTI
Sbjct: 319 PVAGLSYGQSAGLKDDLDVED-NDIGEKKRLAFLDLMLESAQNGA-LITDTEIKEQVDTI 376

Query: 303 MFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVIL 362
           MFEGHDTTAAGSSF L L+GIHQD+Q RV  EL  IFGDS RPATF DTLEMKYLER ++
Sbjct: 377 MFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQRPATFQDTLEMKYLERCLM 436

Query: 363 ESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNF 422
           E+LR+YPPVP+IAR+L  D+ +++ NYVIP G TV + T +LHR PK Y +P VF+PDNF
Sbjct: 437 ETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNF 496

Query: 423 LPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGD 482
           LPE   NRHYY+++PFSAGPRSCVGRKYA            RN+R  S++ E +FKLQ D
Sbjct: 497 LPERQANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTESDFKLQAD 556

Query: 483 IILKRAEGFQMKVEPR 498
           IILKR EGF+++++PR
Sbjct: 557 IILKREEGFRVRLQPR 572


>UniRef50_Q9V3S0 Cluster: Cytochrome P450 4g1; n=62;
           Protostomia|Rep: Cytochrome P450 4g1 - Drosophila
           melanogaster (Fruit fly)
          Length = 556

 Score =  515 bits (1271), Expect = e-145
 Identities = 251/495 (50%), Positives = 340/495 (68%), Gaps = 14/495 (2%)

Query: 6   HVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY 65
           HV       +++ + LGY   +G  ++ WLG+ L+VFL +  DIE+IL+ H H+ KA EY
Sbjct: 70  HVAAGLSNAEILAVGLGYLNKYGETMKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEY 129

Query: 66  RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT 125
           R+FKPW G+GLLIS+G  WR HRKMIAPTFH +ILKSFV  F  +S  VV ++  E GK+
Sbjct: 130 RYFKPWFGDGLLISNGHHWRHHRKMIAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGKS 189

Query: 126 FDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVF 185
           FDVHDYMS TTVDILL TAMG+ +  +    F+YA AV+ MCDIIH+R  K   R + ++
Sbjct: 190 FDVHDYMSQTTVDILLSTAMGVKKLPEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIY 249

Query: 186 KLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAK 245
           K T   ++  +++ II G+T+KV+K++KE + E +++ I+    EE +       A+   
Sbjct: 250 KFTKLREKGDRMMNIILGMTSKVVKDRKENFQE-ESRAIV----EEISTPVASTPASKK- 303

Query: 246 TLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFE 305
                  +G RDDLD  DENDVG K+RLA LD M+E ++N   + ++ +I +EV+TIMFE
Sbjct: 304 -------EGLRDDLDDIDENDVGAKRRLALLDAMVEMAKNPDIEWNEKDIMDEVNTIMFE 356

Query: 306 GHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD-RPATFADTLEMKYLERVILES 364
           GHDTT+AGSSF LC++GIH+D+QA+V+ E   IFGD+  R  TFADT+EMKYLERVILE+
Sbjct: 357 GHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCTFADTMEMKYLERVILET 416

Query: 365 LRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP 424
           LRLYPPVP+IAR+L+ D+ +++  Y +P GTTV++  + +HR+P  Y +P  F+PDNFLP
Sbjct: 417 LRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLP 476

Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDII 484
           E   NRHYYS+IPFSAGPRSCVGRKYA            RN+   S   E +FKLQ DII
Sbjct: 477 ERMANRHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNYIVHSTDTEADFKLQADII 536

Query: 485 LKRAEGFQMKVEPRK 499
           LK   GF + +E R+
Sbjct: 537 LKLENGFNVSLEKRQ 551


>UniRef50_Q967Y5 Cluster: Cytochrome P450 CYP4G13v2; n=4;
           Neoptera|Rep: Cytochrome P450 CYP4G13v2 - Musca
           domestica (House fly)
          Length = 552

 Score =  496 bits (1223), Expect = e-139
 Identities = 246/472 (52%), Positives = 317/472 (67%), Gaps = 13/472 (2%)

Query: 28  GNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSH 87
           G  +R+ LG   +VFL +  D+EI LN + H++K+ EYR+F+PW G GLLIS G  WR H
Sbjct: 88  GETVRILLGHMNVVFLTNPADLEIFLNGYKHLEKSVEYRYFQPWFGNGLLISKGHHWRHH 147

Query: 88  RKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGI 147
           RKMIAPTFH +ILKSFV  F ++S  V  +  S+VG+ FD H YMS TTVDILL TAMG 
Sbjct: 148 RKMIAPTFHQSILKSFVPTFVKHSKAVSGRFASKVGQEFDCHKYMSETTVDILLTTAMGC 207

Query: 148 SRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNK 207
             + + E   +YA AVM MCDIIH R  K + R +   + T   +   KL+ +I  +T K
Sbjct: 208 KVQPETEKSAEYAQAVMDMCDIIHIRQLKLFYRLDSTIRFTKLREHDNKLMNVILSMTRK 267

Query: 208 VIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDV 267
           V++++K+ +   + +GI+  T E+      ++ A  AK       +G RDDLD  DEND+
Sbjct: 268 VVEDRKKNF-NAEERGIVDRTAED-----AKLKAKAAKK------EGLRDDLDDIDENDI 315

Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327
           GEK+RLA LD M+E  +N   K +D ++ +EV+TIMFEGHDTTAAGSSF LC+LGIHQDV
Sbjct: 316 GEKRRLALLDAMMEMEKNPDIKWTDKDVMDEVNTIMFEGHDTTAAGSSFALCMLGIHQDV 375

Query: 328 QARVYDELYQIFGDS-DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386
           Q RV++E   IFGD  +R  TFADTL+M YLERVI E+ RL+PPVP+IARK   DV + +
Sbjct: 376 QQRVFEEQQAIFGDDLNRDCTFADTLQMSYLERVICETQRLFPPVPLIARKAEEDVNLKS 435

Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446
             Y I  GTTVV+  + +HR+   Y DPE FNPDNFLPE T NRHYY+YIPFSAGPRSCV
Sbjct: 436 GPYTIAKGTTVVLLQYFVHRRADIYPDPEKFNPDNFLPERTANRHYYAYIPFSAGPRSCV 495

Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           GRK+A            RN+R  S   +K+F+LQGDIILK A GF + +E R
Sbjct: 496 GRKFAMLQLKVLLSTIIRNYRVSSTRTQKDFQLQGDIILKMANGFNITLEKR 547


>UniRef50_A0A8M5 Cluster: Cytochrome P450 4 family; n=1; Daphnia
           magna|Rep: Cytochrome P450 4 family - Daphnia magna
          Length = 526

 Score =  363 bits (894), Expect = 4e-99
 Identities = 201/494 (40%), Positives = 291/494 (58%), Gaps = 42/494 (8%)

Query: 14  QKLVNLALGYAQTFGN-----VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFF 68
           ++++NL L     FG      +IR W+G   + F   A+ +E +L+S+  I K+ EY F 
Sbjct: 67  EEIMNLLLLLHVVFGRLSPSGIIRAWIGPLPMFFATTAEAVEAVLSSNKIITKSREYDFL 126

Query: 69  KPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDV 128
            PWL  GLL S+G KW++ RK++ P FH  IL+ FV +FN+ S  +V KL   V K  D+
Sbjct: 127 HPWLNTGLLTSTGSKWQTRRKLLTPAFHFKILEDFVHVFNEQSLILVNKLNQAVAKDKDL 186

Query: 129 H--DYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFK 186
           +   +++  T+DI+ ETAMG + + Q ++   Y  AV  M  +I  R  +F++  + +FK
Sbjct: 187 NIFPFVTLCTLDIICETAMGRNVEAQSKTDSAYVQAVYNMSQLIQHRQVRFYLWLDWMFK 246

Query: 187 LTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKT 246
           L+S + +Q K LGI+HG TNKVI+       E KA         E    S +I   +   
Sbjct: 247 LSSHWPEQRKTLGILHGFTNKVIQ-------ERKA---------EHQQRSSDIAEPSKDV 290

Query: 247 LSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEG 306
             D VF                 K+RLAFLDL+IE SQ GT  +S  +I+EEVDT MFEG
Sbjct: 291 TEDAVFS----------------KRRLAFLDLLIEFSQGGT-VLSASDIREEVDTFMFEG 333

Query: 307 HDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLR 366
           HDTT+A  ++ + L+G H +VQ  V +EL ++FGDSDRPAT AD  E+KYLE  + E+LR
Sbjct: 334 HDTTSAAITWSIFLIGSHPEVQEMVNEELDRVFGDSDRPATMADLSELKYLECCVKEALR 393

Query: 367 LYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPEN 426
           LYP VP+I+R    D  I      IPAGT+V I ++ LHR PKY+ DPE++ P  FL E+
Sbjct: 394 LYPSVPIISRTCVEDTVIGGDE--IPAGTSVSICSYYLHRDPKYFPDPELYQPKRFLAEH 451

Query: 427 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486
            + RH YSY+PFSAGPR+C+G+++A            RNF   S    +E  L  ++IL+
Sbjct: 452 AERRHPYSYVPFSAGPRNCIGQRFALMEEKAVLSAILRNFHVQSLDKREEIILLAELILR 511

Query: 487 RAEGFQMKVEPRKR 500
             +G ++++EP+K+
Sbjct: 512 PRDGIRVRLEPKKK 525


>UniRef50_Q9VA27 Cluster: Cytochrome P450 4c3; n=15; Coelomata|Rep:
           Cytochrome P450 4c3 - Drosophila melanogaster (Fruit
           fly)
          Length = 535

 Score =  363 bits (892), Expect = 8e-99
 Identities = 197/498 (39%), Positives = 295/498 (59%), Gaps = 36/498 (7%)

Query: 3   LNIHVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKA 62
           + ++V  + L  +++ +   +    G + RVW G+   V L + + +E ILNS   ++K+
Sbjct: 71  IEMNVDHDELFNRVIGMQKLWGTRIG-INRVWQGTAPRVLLFEPETVEPILNSQKFVNKS 129

Query: 63  TEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV 122
            +Y +  PWLGEGLL S+  KW S RK++ P FH  IL  F+ +FN+ S  +  KL  EV
Sbjct: 130 HDYDYLHPWLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEV 189

Query: 123 G-KTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRS 181
           G + F++  Y++  T+DI+ ETAMG     Q  S  +Y  AV  +  I+  R  K W++S
Sbjct: 190 GSEAFNLFPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQS 249

Query: 182 EIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILA 241
           + +F LT+ +K     +  +HG +N VI+       E KA+  I   L+E  +++     
Sbjct: 250 DFIFSLTAEYKLHQSYINTLHGFSNMVIR-------ERKAELAI---LQENNNNNN---- 295

Query: 242 NNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDT 301
           NNA    D                DVG+KKRLAFLDL+I++S+ GT  +S+ +I+EEVDT
Sbjct: 296 NNAPDAYD----------------DVGKKKRLAFLDLLIDASKEGT-VLSNEDIREEVDT 338

Query: 302 IMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDS-DRPATFADTLEMKYLERV 360
            MFEGHDTT+A  S+ L LLG H + Q RV +EL  IFGD  + PAT  + ++M+YLE  
Sbjct: 339 FMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECC 398

Query: 361 ILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPD 420
           I +SLRL+P VP++AR +  DV I  K  ++PAGT  +I T+ LHR P+ +  PE FNPD
Sbjct: 399 IKDSLRLFPSVPMMARMVGEDVNIGGK--IVPAGTQAIIMTYALHRNPRVFPKPEQFNPD 456

Query: 421 NFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQ 480
           NFLPEN   RH ++YIPFSAGPR+C+G+K+A            R ++  +    ++  L 
Sbjct: 457 NFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLL 516

Query: 481 GDIILKRAEGFQMKVEPR 498
           G++IL+  +G ++K+ PR
Sbjct: 517 GELILRPKDGLRVKITPR 534


>UniRef50_Q170T4 Cluster: Cytochrome P450; n=5; Endopterygota|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 497

 Score =  318 bits (781), Expect = 2e-85
 Identities = 181/478 (37%), Positives = 269/478 (56%), Gaps = 45/478 (9%)

Query: 24  AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK 83
           ++ +G + RVW+G++L +F  +  D E +L+S   I K+  Y+F  PWLG GLL+S+  K
Sbjct: 61  SRKYGTMFRVWVGTRLALFCTNTPDTETVLSSQKLIRKSELYKFLVPWLGNGLLLSTDQK 120

Query: 84  WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILLE 142
           W + RK+I P FH  IL+ F+ +F++ S  +V+KLK E  GK  +V+ Y++   +D++ E
Sbjct: 121 WFNKRKIITPAFHFKILEQFIEVFDRQSGILVQKLKPEASGKLVNVYPYVTLCALDVICE 180

Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202
           TAMG     Q +    Y  AV ++  ++  R  K W RS+ +F L+   K+Q        
Sbjct: 181 TAMGTPINAQTDVDSKYVRAVTELSYLLTTRFVKVWQRSDFLFNLSPDRKRQ-------- 232

Query: 203 GLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFN 262
              +KVIK                  L +FT +   I+    K L D        D   +
Sbjct: 233 ---DKVIK-----------------VLHDFTTN---IIQKRRKELMD------HGDSGIS 263

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
            ++ +G KK++AFLD+++++S +G   ++D EI+EEVDT MFEGHDTT    +F L LL 
Sbjct: 264 GDDSIGSKKKMAFLDVLLQASVDG-KPLTDKEIQEEVDTFMFEGHDTTTIAIAFTLLLLA 322

Query: 323 IHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381
            H +VQ +VY E+ +I G D   PAT+ +  +MKYLE VI ESLRLYPPVP+I RK    
Sbjct: 323 RHPEVQEKVYKEVTEIIGTDLSIPATYRNLQDMKYLEMVIKESLRLYPPVPIIGRKFTEK 382

Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHY-YSYIPFSA 440
            TI     VIP  +   +G  ++HR PK + DPE F+P+ F PE T  +   Y+YIPFSA
Sbjct: 383 TTIG--GNVIPEDSNFNLGIIVMHRDPKLFDDPEKFDPERFSPERTMEQSSPYAYIPFSA 440

Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           GPR+C+G+K+A            RN+R     PE +  +Q  + LK  +G ++   PR
Sbjct: 441 GPRNCIGQKFAMLELKSTLSKVIRNYRLTEAGPEPQLIIQ--LTLKPKDGLKIAFVPR 496


>UniRef50_Q27589 Cluster: Cytochrome P450 4d2; n=8;
           Acalyptratae|Rep: Cytochrome P450 4d2 - Drosophila
           melanogaster (Fruit fly)
          Length = 501

 Score =  299 bits (734), Expect = 1e-79
 Identities = 177/475 (37%), Positives = 262/475 (55%), Gaps = 42/475 (8%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86
           +G + RVW+  +L VF  D  DIE +L+S  HI K   Y+    WLG+GLL+S+G KW  
Sbjct: 65  YGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHG 124

Query: 87  HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKT-FDVHDYMSGTTVDILLETA 144
            RK+I PTFH  IL+ FV IF+Q S  +VE+L+S   GKT  ++   +  T +DI+ ETA
Sbjct: 125 RRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGKTPINIFPVICLTALDIIAETA 184

Query: 145 MGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGL 204
           MG     Q      Y  AV  + +I+ +R    W R + +F+LT    Q T         
Sbjct: 185 MGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLT----QPT--------- 231

Query: 205 TNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDE 264
                    E   ++KA  ++    E       E L NN+K  +        ++++F   
Sbjct: 232 ---------EAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTP------EEEVNF--- 273

Query: 265 NDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324
             +G+K+R+A LD++++S+ +G   +SD +I+EEVDT MFEGHDTT +  SF L  +  H
Sbjct: 274 --LGQKRRMALLDVLLQSTIDGA-PLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRH 330

Query: 325 QDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383
            +VQ R+  E+  + G D   P T  D  E+K++E VI ESLRL+PPVP+I R    DV 
Sbjct: 331 PEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVE 390

Query: 384 ISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443
           I  K+  IPAGT   +G F+L R P+Y++ P+ F P+ F   +    H Y+YIPFSAGPR
Sbjct: 391 IRGKH--IPAGTNFTMGIFVLLRDPEYFESPDEFRPERF-DADVPQIHPYAYIPFSAGPR 447

Query: 444 SCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           +C+G+K+A            R+F  +   PE    +  +I+L+ A G  + ++PR
Sbjct: 448 NCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSM--NIVLRSANGVHLGLKPR 500


>UniRef50_UPI00015B569E Cluster: PREDICTED: similar to cytochrome
           P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 512

 Score =  299 bits (733), Expect = 1e-79
 Identities = 165/461 (35%), Positives = 253/461 (54%), Gaps = 40/461 (8%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           ++  W+G++ IV L     +E+IL S+  I KA  Y + KPWLG+GL+ S+G  W SHR+
Sbjct: 73  MVLAWVGTQPIVILRRPQQMEVILPSNTLITKAATYDYMKPWLGDGLVTSTGELWFSHRR 132

Query: 90  MIAPTFHINILKSFVGIFNQN----SNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 145
           +I P FH  +L+ +  +  +        +  +LK++     ++   +   T+D + ETAM
Sbjct: 133 LITPAFHFGVLEEYGAVMREKVEIFKECIESELKTDPKAPINIFGLVVKYTLDTICETAM 192

Query: 146 GISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205
           G++  TQ      Y  AV     +  +R YK W++   ++  T+  K+    + I+H  T
Sbjct: 193 GVNIDTQRNPESAYVKAVHTYARLTVERFYKPWLKWNAIYYRTNKGKEALNAVKIMHSFT 252

Query: 206 NKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDEN 265
            KVI+ K+    E K K                    + K LSD V             +
Sbjct: 253 EKVIRQKQ---AERKEKSF------------------SNKELSDEV-------------D 278

Query: 266 DVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQ 325
           + G++KR AFLDL++ +S+N +N ++  E++EEVDT MF GHDTT++  S+ L  L    
Sbjct: 279 EFGKRKRKAFLDLLLSASENASNPLTFEELREEVDTFMFAGHDTTSSAISWGLFALANAP 338

Query: 326 DVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIS 385
           ++QA+V+ EL +IFGDS   A      E+KYL+RVI E LRLYP  P+++R+L  D  I 
Sbjct: 339 EIQAKVHKELQEIFGDSGETANSKQLSELKYLDRVIKEVLRLYPSAPMVSRRLTHDTVID 398

Query: 386 TKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSC 445
             N+ +P GT V I  + +H  PK +KDPE F+PD FLPEN ++RH YSY+PFSAGPR+C
Sbjct: 399 --NHHVPKGTFVNIHIYQMHHDPKVWKDPETFDPDRFLPENIRSRHPYSYVPFSAGPRNC 456

Query: 446 VGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486
           +G+K+A            R ++  S +   E K+    IL+
Sbjct: 457 IGQKFALLEVKTALTAILRKWQISSVLKPTEIKMIHTFILR 497


>UniRef50_UPI00015B5D09 Cluster: PREDICTED: similar to cytochrome
           P450 CYP4AB2; n=4; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis
          Length = 519

 Score =  297 bits (730), Expect = 3e-79
 Identities = 157/439 (35%), Positives = 251/439 (57%), Gaps = 30/439 (6%)

Query: 14  QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLG 73
           ++L  L + + + +  + ++W   K ++ ++  DD+E +L S  HI+K+  Y    PW G
Sbjct: 52  EQLWPLGIKWDKQYYPIYKIWTTHKAVIVILHPDDVETLLTSMEHIEKSIMYDMVHPWFG 111

Query: 74  EGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMS 133
            GLL S+G KW+  RK++ P FH ++L+ +  I  +N+  V+  LKS      ++ + ++
Sbjct: 112 TGLLTSTGAKWQKRRKILTPAFHFHVLQKYFDIIVENNEKVMHSLKSNGSVINNLVELLT 171

Query: 134 GTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQ 193
             T+D++ ETAMG +   ++     Y   +  + + +  R  + W + +  F+ TS  ++
Sbjct: 172 YYTLDVICETAMGTTLLDKEHQQ-KYRNVLHDVSNAVIYRLMRPWFQVDWTFRWTSVAEK 230

Query: 194 QTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLS-DTVF 252
           Q K L +IHG + K+IK +KE +   K KG          H+  ++ ++ +     D  +
Sbjct: 231 QKKALEVIHGFSKKIIKERKEYH--EKTKG----------HYLNQLESDQSDDKKEDEEY 278

Query: 253 KGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAA 312
            GYR             KKRLA LDL+I   ++G N+I D  I+EEVDT +FEGHDT+A 
Sbjct: 279 FGYR-------------KKRLAMLDLLIAKQKDG-NQIDDAGIREEVDTFIFEGHDTSAM 324

Query: 313 GSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVP 372
              F + L+  H DVQ R+  E+ ++   S+      +  ++ YLE  I ESLRLYP VP
Sbjct: 325 AMCFAILLIAEHNDVQDRIRAEVKEVLEKSEGKMGVPEIQQLNYLELCIKESLRLYPSVP 384

Query: 373 VIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHY 432
            I+R + +D+ +  KNY++P GT + I  F LHR P ++ DPE F+PD FLP+  Q RH 
Sbjct: 385 FISRGVTKDLHL--KNYIVPKGTLIQINIFSLHRDPNFWPDPEKFDPDRFLPDRFQGRHP 442

Query: 433 YSYIPFSAGPRSCVGRKYA 451
           YSYIPFSAGPR+C+G+K+A
Sbjct: 443 YSYIPFSAGPRNCIGQKFA 461


>UniRef50_Q6VAB7 Cluster: Cytochrome P450 CYP4AB2; n=6;
           Apocrita|Rep: Cytochrome P450 CYP4AB2 - Solenopsis
           invicta (Red imported fire ant)
          Length = 511

 Score =  297 bits (730), Expect = 3e-79
 Identities = 171/462 (37%), Positives = 259/462 (56%), Gaps = 38/462 (8%)

Query: 40  IVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 99
           +VF+   DD+EIILN+  HI K+  Y   +PWLG GLL S G KW   RK++ PTFH NI
Sbjct: 78  LVFIRHPDDLEIILNNTKHISKSNLYDALRPWLGMGLLTSGGSKWHLRRKILTPTFHFNI 137

Query: 100 LKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRKTQDESGFD 158
           L+ FV I  +   ++   LK+  G  T D+  ++S  T++ + ETAMG S +        
Sbjct: 138 LQQFVEILIEEGESMTRSLKNAGGTITKDLVPFISEYTLNAICETAMGTSLQEMGSFQQQ 197

Query: 159 YAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLE 218
           Y  AV +M +++  R  + W++ + +F LTS  ++Q KLL I+HG T KVI  +K+ +  
Sbjct: 198 YRKAVHRMGELLVYRAMRPWLKYDWIFSLTSKGREQKKLLKILHGFTEKVIAKRKDYHKR 257

Query: 219 NKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVG-EKKRLAFLD 277
            K                G+ L N  K            D+  N+   +G +KKR A LD
Sbjct: 258 TK----------------GQYLKNLNK------------DVVPNETETIGIKKKRFAMLD 289

Query: 278 LMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ 337
           L+I++SQ G   ++D +I+EEVDT MFEG DTT     F+L LL  H+D+Q  V  E+  
Sbjct: 290 LLIQASQEGL--LTDFDIREEVDTFMFEGFDTTGMAMCFILSLLAEHKDIQDCVRKEIDA 347

Query: 338 IFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTV 397
           +  ++          +++YLER I E+LRLYP V  I+R  + +  + T  Y+IPAGT V
Sbjct: 348 VMQENQGKLNMKSLQDLQYLERCIKEALRLYPSVYFISRITSEETELKT--YLIPAGTLV 405

Query: 398 VIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXX 457
           ++  ++ HR   ++ +PEVF+PD FLP+N +NRH YSY+PFSAGPR+C+G+++A      
Sbjct: 406 ILNFYITHRDSNFWPNPEVFDPDRFLPDNIRNRHPYSYLPFSAGPRNCIGQRFALLELKA 465

Query: 458 XXXXXXRNF--RTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
                  NF    +  +  + F +  D+IL+  +  ++K  P
Sbjct: 466 MLVPLIYNFYLEPVDYLENQRFGI--DMILRSLDPCRLKFVP 505


>UniRef50_A0MNW4 Cluster: Cyp4M9; n=20; Obtectomera|Rep: Cyp4M9 -
           Bombyx mandarina (Wild silk moth) (Wild silkworm)
          Length = 505

 Score =  288 bits (706), Expect = 3e-76
 Identities = 166/479 (34%), Positives = 257/479 (53%), Gaps = 35/479 (7%)

Query: 24  AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK 83
           A  + N+ R W      + +   D+IE I++S  HI K+  Y F   WL +GLL+S+G K
Sbjct: 61  ATQWPNLNRFWSFGIGALNIYGPDEIEAIISSTQHITKSPVYNFLSDWLRDGLLLSTGTK 120

Query: 84  WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLET 143
           W+  RK++ P FH N LK F  I  +NS    E LK   GK+ +V   +S  T+  + ET
Sbjct: 121 WQKRRKILTPAFHFNTLKQFCVILEENSQRFTENLKDTEGKSINVVPAISEYTLHSICET 180

Query: 144 AMGISRKTQ-DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202
           AM     ++  E+G  Y  A+ ++ +    R  +    +  ++ L +  KQ   L  I+H
Sbjct: 181 AMRTQLGSETSEAGRSYKNAICELGNQFVHRLARIPPHNNFIYNLFTLGKQNEHL-NIVH 239

Query: 203 GLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFN 262
             T +VIK++++                 +   +G    NN     DT  +     + FN
Sbjct: 240 SFTKRVIKDRRQ-----------------YIRRNG---GNNFDDEKDT--QADEHSIYFN 277

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
                  KK+ A LDL++++ ++G   I +  ++EE+DT MFEGHDTTA G ++ + L+ 
Sbjct: 278 -------KKKTAMLDLLLKAERDGL--IDEIGVQEEIDTFMFEGHDTTATGLTYCIMLIA 328

Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382
            H+ +Q ++ +EL +IFG+S R A   D  +M+YLER I ESLRLYPPVP + R L+ ++
Sbjct: 329 NHKSIQDKIIEELDEIFGESTRAADIEDLSKMRYLERCIKESLRLYPPVPSMGRILSEEI 388

Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442
            ++   Y +PAGT   I  F LHR+   +KDP VF+PD FLP NT+ RH Y+YIPFSAGP
Sbjct: 389 NLN--GYTVPAGTYCHIQIFDLHRREDLFKDPLVFDPDRFLPHNTEGRHPYAYIPFSAGP 446

Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRV 501
           R+C+G+K+A            R +        ++ K   D++L+  E   ++   R +V
Sbjct: 447 RNCIGQKFAILEMKSLLSAVLRRYNLYPITKPEDLKFVLDLVLRTTEPVHVRFVKRNKV 505


>UniRef50_Q9VS79 Cluster: Cytochrome P450 4d8; n=6; Schizophora|Rep:
           Cytochrome P450 4d8 - Drosophila melanogaster (Fruit
           fly)
          Length = 463

 Score =  278 bits (682), Expect = 2e-73
 Identities = 171/482 (35%), Positives = 264/482 (54%), Gaps = 44/482 (9%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82
           Y   FG++ RVW+ ++L++   DA+  E +L+S  H+ K   Y+    WLG GLL+S G 
Sbjct: 19  YVLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGK 78

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILL 141
            W   RK+I PTFH +IL+ FV +F+Q SN  V++L  +  G TFDV+  +    +DI+ 
Sbjct: 79  VWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSICAAALDIIA 138

Query: 142 ETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGII 201
           ETAMG     Q      YA AV +   ++  R    +++ E++F                
Sbjct: 139 ETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFT--------------- 183

Query: 202 HGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDF 261
             LT+  +K ++   +          T++EFT    +++    + L D   K     +D 
Sbjct: 184 --LTHPHLKWRQTQLIR---------TMQEFTI---KVIEKRRQALEDQQSKL----MDT 225

Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321
            DE DVG K+R+A LD+++ S+ +G   +++ EI+EEVDT MFEGHDTT +  SF L  L
Sbjct: 226 ADE-DVGSKRRMALLDVLLMSTVDG-RPLTNDEIREEVDTFMFEGHDTTTSALSFCLHEL 283

Query: 322 GIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380
             H +VQA++ +E+ Q+ G D  RP +  D  E+KY+E VI ESLR+YPPVP++ RKL  
Sbjct: 284 SRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQT 343

Query: 381 DVTISTKNY---VIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIP 437
           D   +   +   VIPAG+ ++IG F +HRQP+ + +P+ F P+    EN      +  IP
Sbjct: 344 DFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERH--ENGSRVAPFKMIP 401

Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
           FSAGPR+C+G+K+A            R +  +      E  +  +I+L+   GFQ+ +  
Sbjct: 402 FSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIV--NIVLRSETGFQLGMRK 459

Query: 498 RK 499
           RK
Sbjct: 460 RK 461


>UniRef50_Q170T0 Cluster: Cytochrome P450; n=12; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 505

 Score =  277 bits (679), Expect = 5e-73
 Identities = 165/477 (34%), Positives = 259/477 (54%), Gaps = 43/477 (9%)

Query: 28  GNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSH 87
           G   R+W+G  LI  + DA  +E IL+S   +DK+ +Y F +PWLG GLL S+G KW S 
Sbjct: 68  GKFYRLWIGPDLIFPITDAKLVEAILSSQKLLDKSVQYDFIRPWLGNGLLTSTGRKWHSR 127

Query: 88  RKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLETAM 145
           RK+I PTFH  IL+ FV IF+Q SN  V +LKS+   G+ FDV   ++   +D++ E+AM
Sbjct: 128 RKIITPTFHFKILEQFVEIFDQQSNIFVGQLKSKAQSGEDFDVFPVVTLCALDVICESAM 187

Query: 146 GISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205
           G     Q  S   Y  AV  M  +   R +K + R    F  T +F    ++        
Sbjct: 188 GTKVNAQLNSDSKYVRAVKDMATVAMARSFKAFAR----FNFTFYFTPYRRM----QDKA 239

Query: 206 NKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDEN 265
            KV+ +  ++ + ++        LE         LA  A T SD             +EN
Sbjct: 240 LKVLHDYTDSVIRSRR-------LE---------LAKGAFTKSD------------ENEN 271

Query: 266 DVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQ 325
           DVG +K++AFLD++++++ +G   + D E++EEVDT MFEGHDTT +  SF++ +L  H 
Sbjct: 272 DVGIRKKVAFLDMLLQATVDG-RPLDDLEVREEVDTFMFEGHDTTTSAISFLIGILAKHP 330

Query: 326 DVQARVYDELYQIFGDS-DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384
           DVQ +VYDE+  + GD  +   T +   ++ YL+ VI E+LRLYP VP+  R L  +  I
Sbjct: 331 DVQQKVYDEVRNVIGDDLNVSVTLSMLNQLNYLDLVIKETLRLYPSVPIYGRMLLENQEI 390

Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPE-NTQNRHYYSYIPFSAGPR 443
           +    V PAG+ + I  + + R P+Y+++P  F P+ F  E + +  + Y Y+PFSAGPR
Sbjct: 391 N--GTVFPAGSNLAIFPYFMGRDPEYFENPLEFRPERFAVETSAEKANPYRYVPFSAGPR 448

Query: 444 SCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500
           +C+G+K+A            R++  +        ++  +++L+   G  +++  R R
Sbjct: 449 NCIGQKFAVAEIKSLISKLVRHYEVLPPKQPNSERMIAELVLRPEGGVPVRIRSRVR 505


>UniRef50_UPI0000D55ACE Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 501

 Score =  275 bits (674), Expect = 2e-72
 Identities = 160/480 (33%), Positives = 258/480 (53%), Gaps = 46/480 (9%)

Query: 23  YAQTFGNVIRVWLGS-KLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSG 81
           YA+  G ++ +  G  K  +   D   +E +L+S+  + K+   RF +PW+G GL+ + G
Sbjct: 64  YAKAHGTMVHLKFGPFKHALLCTDTKFLEFLLSSNKLLKKSVNLRFLEPWIGTGLVTADG 123

Query: 82  -PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG-KTFDVHDYMSGTTVDI 139
            PKW++HRK+I P FH  IL+ FV IF    + +V+KL    G K+ D++ Y++  T+DI
Sbjct: 124 GPKWKTHRKLITPAFHFKILEQFVDIFESGGDILVKKLSEVSGSKSCDIYPYITKCTLDI 183

Query: 140 LLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLG 199
           + ETAMG     Q+     Y  ++ +MC I       F +R+   F    F         
Sbjct: 184 ICETAMGTKVDVQNTENSAYFESIKEMCRI-------FTVRTVGAFLSNDF--------- 227

Query: 200 IIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDL 259
                   + +  K+  ++ KA  ++        +HS E++ N  K L +      +++ 
Sbjct: 228 --------IFRFSKDYKIQTKAVKVLH-------NHSNEVIVNKRKELKE------KNNE 266

Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319
           + +D +++G KK+  FLDL++ ++ +G + +S  EI+EEVDT MF GHDTT   +SF+L 
Sbjct: 267 NTSDIDELGRKKKKVFLDLILSATTDGQS-LSPEEIREEVDTFMFGGHDTTGTATSFILY 325

Query: 320 LLGIHQDVQARVYDELYQIFGDSDRP-ATFADTLEMKYLERVILESLRLYPPVPVIARKL 378
            +  +++ Q ++ +E  Q+FGD   P  T++   EMKYLE  I E LRLY PVP+  R +
Sbjct: 326 CIANNKEAQEKILEEQKQLFGDERSPKVTYSTLQEMKYLENAIKEGLRLYSPVPIYGRLI 385

Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPF 438
           ++D   +    +IP G  V+I    +H  PKYY +PE F+P  F  ENT  +  +++IPF
Sbjct: 386 DQDTEYN--GTMIPKGVGVIIFAHGIHMNPKYYPNPEKFDPSRF--ENTTGKDPFTFIPF 441

Query: 439 SAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           SAGPR+C+G+KYA            RNF      P  E  L  + +LK   G ++ ++ R
Sbjct: 442 SAGPRNCIGQKYAMLEIKSLVSKVVRNFELFPASPTHEMHLAPETVLKSLNGVKIGLKMR 501


>UniRef50_UPI00015B604A Cluster: PREDICTED: similar to cytochrome
           P450 CYP4AB2; n=8; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis
          Length = 519

 Score =  272 bits (666), Expect = 2e-71
 Identities = 158/480 (32%), Positives = 255/480 (53%), Gaps = 36/480 (7%)

Query: 14  QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLG 73
           +K  N+     + +  + + WLG    V +   DD+EI+L+S  H++K + Y    PWL 
Sbjct: 59  KKTWNVIRDLNKNYYPIAKFWLGPYPYVSIHHPDDLEILLSSTKHLEKGSAYTVLHPWLR 118

Query: 74  EGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFD-VHDYM 132
            GLL SSG KW+  RK++ P FH  IL+ ++ I N++    +E L++E  +T   +  + 
Sbjct: 119 TGLLTSSGSKWQQRRKILTPAFHFKILRKYMDITNEHGKKFIEALRTENSETVQSLMPFC 178

Query: 133 SGTTVDILLETAMGISR-KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFF 191
           S  T+ I+ ETAMGI+  K   +   +Y  AV  + ++I  R  + +++  ++  + +F 
Sbjct: 179 SNYTLHIICETAMGIALDKIDTKISKEYKNAVADIANLIMYRVMRPYLKEWMMLPVWTF- 237

Query: 192 KQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTV 251
                  G +   T + +    +T L  + +           +H         K   +  
Sbjct: 238 -------GRLQTQTLRTLHKFTKTVLTERRE-----------YH---------KRSDNKY 270

Query: 252 FKGYRDDL-DFN-DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDT 309
            KG+ DD  D N D+  +G KK+LA LDL++ ++Q+G     D  IKEEVDT MF GHDT
Sbjct: 271 LKGFHDDTYDVNKDDVAIGGKKKLAMLDLLLSAAQDGLT--DDEGIKEEVDTFMFAGHDT 328

Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYP 369
           T     + + LL  H+++Q +   E+ ++  +S+      +  ++ YLER I ESLR++P
Sbjct: 329 TGIALVYAIMLLAEHKEIQEKARAEVIEVLTESNGEIGTLEIQKLHYLERCIKESLRIFP 388

Query: 370 PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQN 429
           PV  ++R +  D+ +  KNYV+PAGT +    F LHR P ++ +PE ++PD FLPEN Q 
Sbjct: 389 PVSALSRTVKEDIQL--KNYVVPAGTEIGCHIFDLHRDPNFWPEPEKYDPDRFLPENIQG 446

Query: 430 RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAE 489
           RH Y+YIPFSAG R+C+G+K+A             NF        K+ KL  D++ +  E
Sbjct: 447 RHPYAYIPFSAGSRNCIGQKFAMMELKSLTARILYNFELEPVSQTKDMKLTLDLVTRPLE 506


>UniRef50_A7SWY9 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 509

 Score =  272 bits (666), Expect = 2e-71
 Identities = 161/484 (33%), Positives = 261/484 (53%), Gaps = 42/484 (8%)

Query: 21  LGYAQTFGNVIRVWLG-SKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLIS 79
           +G+   F  +  +WL  +K  + + +   +E+IL+S  HI KA  Y F  PWLG GLL S
Sbjct: 62  MGWCSQFKGIFCLWLSFAKPFLLIYEPKTVEVILSSSKHITKAQFYDFLLPWLGTGLLTS 121

Query: 80  SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG-KTFDVHDYMSGTTVD 138
           +G KW+  R++I PTFH  IL  FV +F+Q S  +V  +KS+   K F++   ++   +D
Sbjct: 122 TGEKWKKRRRLITPTFHFKILNDFVQVFDQQSQLMVSIIKSQPSDKVFNIFPLIACCALD 181

Query: 139 ILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLL 198
           I+ +TAMG++   Q  S  +Y   V++M ++I  R  + W+    ++ LT+  ++     
Sbjct: 182 IIGKTAMGVNINAQKNSSSEYVKGVIRMSELIQSRQKRPWVHPAFLYCLTNEGREH---- 237

Query: 199 GIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDD 258
                  NK+IK     +L +    +I   ++E  +   E                 +D+
Sbjct: 238 -------NKIIK-----FLHDFTNQVITERIQERLYSPKE-----------------QDE 268

Query: 259 LDFNDENDVGEKKRL-AFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFV 317
            + +DE     K+RL AFLD+++ +   G  +I    ++EEVD  MFEGHDTTAA  ++ 
Sbjct: 269 TEESDEFTGRRKRRLVAFLDMLLNAYDAG--EIDVEGVREEVDIFMFEGHDTTAAAMAWA 326

Query: 318 LCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLE-MKYLERVILESLRLYPPVPVIAR 376
           + LLG H DVQ +   E+ + F  +    T AD+L+ +KYLE VI E+LR++P VP   R
Sbjct: 327 VQLLGEHPDVQRKAQAEVDEFFATNSGKLT-ADSLKGLKYLECVIKETLRIFPSVPFFGR 385

Query: 377 KLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYI 436
            L  D+ +  +  +IP GT V + T  LHR P+ +  P  FNPD FLPEN++ RH Y+++
Sbjct: 386 SLVEDLELEGR--LIPKGTDVGVITIGLHRNPEVWPSPMKFNPDRFLPENSEGRHPYAFV 443

Query: 437 PFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496
           PFSAG R+C+G+++A             NF  +S     + K   ++I +  +G  + + 
Sbjct: 444 PFSAGSRNCIGQRFALLEEKVVLAYILHNFDIVSTEKSTKIKTCAELITRPRDGIFVSLT 503

Query: 497 PRKR 500
            R++
Sbjct: 504 TREQ 507


>UniRef50_Q9Y1T8 Cluster: Cytochrome P450 4W1; n=3; Arthropoda|Rep:
           Cytochrome P450 4W1 - Boophilus microplus (Cattle tick)
          Length = 549

 Score =  256 bits (627), Expect = 1e-66
 Identities = 150/495 (30%), Positives = 252/495 (50%), Gaps = 41/495 (8%)

Query: 11  NLTQKLVNLALGYAQTFGN--VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFF 68
           +++  L  +A G+++ + N  + R +  +  ++ L  A+ +E +L S+  + K  EY   
Sbjct: 83  DISTHLFQVAFGFSRIYKNHGMFRFYDATHPVLVLFKAEAVEELLTSNTVLKKGHEYELI 142

Query: 69  KPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TF 126
           KPWLG GLL SSG KWRS RK++ P FH  IL+ F+   N  SN +V KL  ++GK  + 
Sbjct: 143 KPWLGTGLLTSSGSKWRSRRKLLTPAFHFRILEDFLPAVNDQSNILVRKL-GQLGKDRSC 201

Query: 127 DVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYK--FWMRSEIV 184
           ++   ++   +DI+ ET MG +   Q     +Y  A+  +     +R     +W+  + +
Sbjct: 202 NIVPLVTLCALDIICETIMGYTINAQSNQDSEYVQAIKVLGHSFTRRLETPLYWI--DAI 259

Query: 185 FKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNA 244
           F+L+   ++  + +  +H  T KVI+       E K + +  P L+E             
Sbjct: 260 FQLSKPGREFARKVKELHQFTLKVIR-------ERKREILSCPELQE------------- 299

Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMF 304
                     Y +    +D   +    R  FLD+++          ++  ++EEVDT MF
Sbjct: 300 ---------SYEETASESDVYGLKGTARKPFLDILLREHIKDPENFTEEHVREEVDTFMF 350

Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILE 363
           EGHDTTA G S+ + L+ +H + Q  ++ EL  IFG D  RP T  D  +MKY+E  + E
Sbjct: 351 EGHDTTAMGMSWAIYLIALHTEHQDLIHQELDTIFGSDKTRPVTSEDLKQMKYMECCLKE 410

Query: 364 SLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFL 423
           S RLYP VP I+RK   D  I  +   +P GT + +  + LH   + +  P+ F PD F 
Sbjct: 411 SQRLYPSVPFISRKCEEDAVICGRK--VPKGTDIQVAIYNLHHDEQVFPKPDEFRPDRFF 468

Query: 424 PENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDI 483
           PEN + RH ++++PFSAGPR+C+G+++A            RN++ ++     +  +  ++
Sbjct: 469 PENVRGRHAFAFVPFSAGPRNCIGQRFAMMEEKVVIANILRNYKLVALHYRDKIHVMAEL 528

Query: 484 ILKRAEGFQMKVEPR 498
           +L+   G  +   PR
Sbjct: 529 VLRPTSGLHVIFIPR 543


>UniRef50_Q9NB96 Cluster: P450 CYP319A1; n=2; Parasitiformes|Rep:
           P450 CYP319A1 - Boophilus microplus (Cattle tick)
          Length = 531

 Score =  255 bits (625), Expect = 2e-66
 Identities = 151/470 (32%), Positives = 242/470 (51%), Gaps = 32/470 (6%)

Query: 34  WLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAP 93
           +LG++  + +  A+ +E+ LN+     K+  Y     WL  GLL S+GPKW+S R+M+ P
Sbjct: 89  YLGTRPCITIYKAEHVEVFLNNRHTQSKSIHYELLHSWLRTGLLTSAGPKWKSRRRMLTP 148

Query: 94  TFHINILKSFVGIFNQNSNNVVEKLKSEVGKTF-DVHDYMSGTTVDILLETAMGISRKTQ 152
            FH  IL+ FV   N+ +     ++   + + + DV    +   +D+LLET MG++    
Sbjct: 149 AFHFKILEDFVAPMNKMARLTAARITDRIKEPWIDVVPMAAACALDVLLETIMGVTNTND 208

Query: 153 DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNK 212
                 Y   V  + + + +R    W+  + ++  T   +Q  K +  IH  T KVI  +
Sbjct: 209 GGESQRYVKNVNSVAERMVRRSQAPWLVLDCLYYRTEDGRQYQKNVSAIHAFTTKVISKR 268

Query: 213 KETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKR 272
           +E  +                    EI A N+K   D   K    D DF+        KR
Sbjct: 269 REEIIN-------------------EIHAANSK--KDNTPKM---DEDFHLTGRTF--KR 302

Query: 273 LAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVY 332
           L F+D+++  S    + ++  +I+EEVDT MFEGHDTTA G ++ L ++  H  VQA+++
Sbjct: 303 LTFIDILLRYSIEVDSTLTTDDIREEVDTFMFEGHDTTAMGIAWSLYMIASHHHVQAKIH 362

Query: 333 DELYQIF-GDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVI 391
            EL  +   D D   T     E+KY +RV+ E  RL+P VPVI R  + D+++    +V+
Sbjct: 363 KELDSVLQSDLDADITLEKIKELKYFDRVLKECQRLFPSVPVIGRATSEDISLG--KHVV 420

Query: 392 PAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           PA + V I  + LHR    + DPEVF+PD FLPEN  +   Y+Y+PFSAGPR+C+G++YA
Sbjct: 421 PADSDVDIFIYALHRDQVCFPDPEVFDPDRFLPENVVHPAPYAYVPFSAGPRNCIGQRYA 480

Query: 452 XXXXXXXXXXXXRNFRTISEIPEK-EFKLQGDIILKRAEGFQMKVEPRKR 500
                       R F T+  + ++ +  L  +++L+   G ++   PR R
Sbjct: 481 LMEVKIIVATILRRF-TLEAVDQRDQLMLACELVLRPLNGLKVSFTPRSR 529


>UniRef50_Q9N574 Cluster: Cytochrome p450 family protein 31A3; n=4;
           Nematoda|Rep: Cytochrome p450 family protein 31A3 -
           Caenorhabditis elegans
          Length = 511

 Score =  254 bits (621), Expect = 5e-66
 Identities = 161/484 (33%), Positives = 251/484 (51%), Gaps = 36/484 (7%)

Query: 19  LALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLI 78
           + +GY      +  +W+G    + L  AD +E I +S  H++K   Y   +PWLG  +L 
Sbjct: 60  IGMGYLYPDPRMCLLWIGPFPCLMLYSADLVEPIFSSTKHLNKGFAYVLLEPWLGISILT 119

Query: 79  SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTV 137
           S   +WR  RK++ PTFH +ILK F+ IFN+ S  +V+K+ S    +  DV   ++  T+
Sbjct: 120 SQKEQWRPKRKLLTPTFHYDILKDFLPIFNEQSKILVQKMCSLGAEEEVDVLSVITLCTL 179

Query: 138 DILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKL 197
           DI+ ET+MG +   Q     +Y  AV                    + KL S  K+    
Sbjct: 180 DIICETSMGKAIGAQLAENNEYVWAV------------------HTINKLIS--KRTNNP 219

Query: 198 LGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRD 257
           L     + N  I N  ++++  K   I+      F    G       + L D   K   +
Sbjct: 220 L-----MWNSFIYNLYDSFIIKKVNSIL-----FFRTEDGRTHEKCLRILHDFTKKVIVE 269

Query: 258 DLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFV 317
             +   END   + RLAFLDL++E  ++G  ++ + +++ EVDT MFEGHDTT+ G  + 
Sbjct: 270 RKEALQENDYKMEGRLAFLDLLLEMVKSG--QMDETDVQAEVDTFMFEGHDTTSTGLMWA 327

Query: 318 LCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARK 377
           + LLG H +VQ +V  EL ++ GD D   T      MKYLE  + E+LRL+P VP+I R+
Sbjct: 328 IHLLGNHPEVQRKVQAELDEVMGD-DEDVTIEHLSRMKYLECALKEALRLFPSVPIITRE 386

Query: 378 LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIP 437
           L+ D  I   N  IP G T ++  +++HR P  +KDP+VF+PD FLPEN+  R  +++IP
Sbjct: 387 LSDDQVIGGVN--IPKGVTFLLNLYLVHRDPSQWKDPDVFDPDRFLPENSIARKSFAFIP 444

Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
           FSAG R+C+G+++A            RNF   +     E + + +II++      MK+  
Sbjct: 445 FSAGSRNCIGQRFALMEEKVIMAHLLRNFNVKAVELMHEVRPKMEIIVRPVTPIHMKLTR 504

Query: 498 RKRV 501
           R+ +
Sbjct: 505 RRPI 508


>UniRef50_UPI00015B4DC8 Cluster: PREDICTED: similar to corpora
           allata cytochrome P450; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to corpora allata cytochrome P450 -
           Nasonia vitripennis
          Length = 513

 Score =  248 bits (607), Expect = 3e-64
 Identities = 150/478 (31%), Positives = 249/478 (52%), Gaps = 42/478 (8%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82
           +AQ FG++  +W+G +  VF+   + +  +L+S  HIDK+ EY + KPWLG GL+ S+G 
Sbjct: 75  WAQEFGDIYLLWVGLRPFVFVYRMEAVGTLLSSRQHIDKSLEYEYLKPWLGSGLITSTGE 134

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHDYMSGTTVDILL 141
           +W + RK++ PTFH  +LK +  +  + ++  VE L+SE+GK  FD+  +     +D + 
Sbjct: 135 RWLARRKLLTPTFHSELLKGYFRVTLREADTFVECLRSEIGKLEFDIVPFAKRAALDTIC 194

Query: 142 ETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGII 201
             AMG     Q     +Y  AV ++   I QR +     + I+ K    FK  T  LG  
Sbjct: 195 VCAMGHQLNAQVNRRNEYVQAVQRLT-AISQRRF-----TSILLKPELLFKVST--LGRE 246

Query: 202 HGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDF 261
           H    +VI        E+   G+I  T  ++    G  L   A+                
Sbjct: 247 HDRALRVI--------EDFVNGVITDTKRDWL---GSRL-RRARA--------------- 279

Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321
              N+  + +    LDL+++  QNG  K++D+++++EV+T MF GHDT     S++L  L
Sbjct: 280 -SNNNERKPRPETLLDLLLQMVQNG-EKLTDNDLRDEVNTFMFAGHDTVGMSVSWILYSL 337

Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381
           G H + Q R+  E+  +   ++    F     + +L   + E+ RLYP  P+IAR++N  
Sbjct: 338 GRHPEYQERIIREVEDLLA-AEGELGFESYNRLHWLGACVKEAWRLYPVTPLIARQINSP 396

Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441
           +T+  +N+ IP GTTV+I +++LHR P+Y+ +PE F P+ FLP        +++IPFSAG
Sbjct: 397 ITL--QNHDIPVGTTVLINSYLLHRDPRYFPEPERFKPERFLP-GASKPPSFAFIPFSAG 453

Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
            R+C+G K+A            R +R  + + E +  L   ++L    G Q+ + PR+
Sbjct: 454 SRNCIGYKFATIEVKVTVLALLRAYRFRAILREDQLHLLSQVVLDNVGGIQLSITPRQ 511


>UniRef50_Q4R1I7 Cluster: Cytochrome P450; n=1; Papilio xuthus|Rep:
           Cytochrome P450 - Papilio xuthus
          Length = 506

 Score =  239 bits (584), Expect = 2e-61
 Identities = 152/473 (32%), Positives = 242/473 (51%), Gaps = 43/473 (9%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           ++R WLG  L   +VD  D+E+IL +   ++K   +RF +  +G GL+ +    WR  RK
Sbjct: 71  ILRGWLGHILYFIVVDPVDVEVILKTS--LEKDDLHRFIRNVIGNGLIFAPVSIWRRRRK 128

Query: 90  MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTF-DVHDYMSGTTVDILLETAMGIS 148
           +  P F   I+ +F+ +F + S  +V  L +  G  +  +  Y+   T+D + ET MGI+
Sbjct: 129 ITVPAFSPKIVDTFMEVFAEQSEKLVSVLAACAGNGYIAMEPYLCRYTLDSVCETTMGIT 188

Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKV 208
              Q+     Y  A+  + +++ +R +  W++ + ++K   FF Q        H    K 
Sbjct: 189 TNAQNNPNAPYLKALKNILNLVCERIFHLWLQPDWLYK---FFSQSKS-----HQKYTKE 240

Query: 209 IKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVG 268
           ++   +  ++NK + I                    K L   V      D +F   N   
Sbjct: 241 MQGFVDEVIQNKRREI-----------------KKEKDLKSEV------DRNFGLSN--- 274

Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328
             K  +FLDL+IE S  G N  +D E++EE+ T+   G DTT     + L LL ++  VQ
Sbjct: 275 -YKTQSFLDLLIEFS-GGENGYTDLELREEILTLTIAGTDTTGISIGYTLKLLAMYPKVQ 332

Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
            ++Y EL  +FG SDR     D  ++KYLER++ ESLRLYPP P I RK+  D+++ +  
Sbjct: 333 DKLYQELLDVFGTSDRRIVKEDLSKLKYLERIVKESLRLYPPGPFIIRKVLEDISLPS-G 391

Query: 389 YVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447
            V PAG+   +  + LHR PKY+  D EVF+PD FLPE    +H  SYIPFS+GPR+C+G
Sbjct: 392 RVFPAGSGAAVSIWGLHRDPKYWGPDAEVFDPDRFLPERFNLKHACSYIPFSSGPRNCIG 451

Query: 448 RKYAXXXXXXXXXXXXRNFRTISEI--PEKEFKLQGDIILKRAEGFQMKVEPR 498
            +YA            R ++ + E   P    K + DI++K  + +++ +E R
Sbjct: 452 YQYALMSMKTVLSAIVRRYKIMGEESGPVPHIKSKIDIMMKAVDDYKICLEKR 504


>UniRef50_O45120 Cluster: Family 4 cytochrome P450; n=2; Coptotermes
           acinaciformis|Rep: Family 4 cytochrome P450 -
           Coptotermes acinaciformis
          Length = 501

 Score =  237 bits (581), Expect = 4e-61
 Identities = 115/235 (48%), Positives = 157/235 (66%), Gaps = 3/235 (1%)

Query: 264 ENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323
           +N++G K+R AFLDLM+++SQ+G + ++D EI+EEVDT MFEGHDTT +  SF +  L  
Sbjct: 270 QNELGLKRRHAFLDLMLQASQDGAS-LTDEEIREEVDTFMFEGHDTTTSALSFTMWCLAK 328

Query: 324 HQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383
           +QDVQ +   EL QIFGDS R ATF D  EMKYLE+VI E+LRLYP V    R+L  + T
Sbjct: 329 YQDVQEKAVVELKQIFGDSTRDATFRDLQEMKYLEQVIKETLRLYPSVNCFGRQLTENFT 388

Query: 384 ISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443
           +   +YV PAG  V I  + LHR+P+Y+ DPE F+PD FLPEN   RH Y Y+PFSAGPR
Sbjct: 389 VG--DYVNPAGANVWIYPYHLHRRPEYFPDPERFDPDRFLPENCVGRHPYCYVPFSAGPR 446

Query: 444 SCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           +C+G+K+A            R+F+ I        + + D +L+ A G ++K++PR
Sbjct: 447 NCIGQKFAILELKSTISQVLRSFKVIESDCNGNIRYKLDFVLRSASGLKVKLQPR 501



 Score =  130 bits (314), Expect = 8e-29
 Identities = 70/200 (35%), Positives = 108/200 (54%), Gaps = 1/200 (0%)

Query: 19  LALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLI 78
           L  G     G ++R+W G+ LIV L +A  +E +L+S   IDKA  YRF  PWLG GLL 
Sbjct: 59  LVEGLIYKHGTIVRLWSGAYLIVILTEAKYVEALLSSTSQIDKAYTYRFVWPWLGSGLLT 118

Query: 79  SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTV 137
           S+G    +  +    +F +   + F G   Q    +VEK    V G  FDV  YM+   +
Sbjct: 119 STGQALGNPPQAADSSFPLQGTREFRGCVQQKWKILVEKFSRHVNGPEFDVTPYMTLCAL 178

Query: 138 DILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKL 197
           D + ET+MG++   Q +S  +Y  A+  + +I+  R  K W  S+  F+L++  ++Q K 
Sbjct: 179 DNMSETSMGVTLNAQKDSDSEYVRAIHSLGEIVFTRSGKPWYHSDTTFRLSTLGREQQKN 238

Query: 198 LGIIHGLTNKVIKNKKETYL 217
           L I+H  T  VI+++K+  L
Sbjct: 239 LAILHSFTRSVIRSRKQELL 258


>UniRef50_Q170S9 Cluster: Cytochrome P450; n=2; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 497

 Score =  234 bits (572), Expect = 5e-60
 Identities = 157/476 (32%), Positives = 246/476 (51%), Gaps = 43/476 (9%)

Query: 15  KLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGE 74
           ++  L   YAQ +G   ++    +  +     D  E ILN+  +  K+ +Y     W+G 
Sbjct: 52  EIFKLLRRYAQQYGTAYKLSFWYQYTLVFAKPDIAEKILNTQSYASKSEDYDKVAEWIGY 111

Query: 75  GLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSG 134
           GLLIS G KW   RK++ P FH  IL+SFV +FN+ S+ +  KL S  G   DV   +  
Sbjct: 112 GLLISKGEKWFKRRKVLTPGFHFKILESFVRVFNEKSDVLCRKLASYGGSEVDVFPTLKL 171

Query: 135 TTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQ 194
            T+D+L ETA+G S   Q E  F Y  AV ++  I++   ++F+     V  L  F KQ 
Sbjct: 172 YTLDVLCETALGYSCNAQTEDSF-YPAAVEELMSILY---WRFFNLFASVDTLFRFTKQY 227

Query: 195 TKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKG 254
            +         +K+I + +E  L+                    I+    K L++     
Sbjct: 228 RRF--------HKLIGDTREFTLK--------------------IIEEKRKLLNEL---- 255

Query: 255 YRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGS 314
             D+   N+E+D G KK++A LDL++ ++ +G   +SD +I+EEVDT  F GHDTTA+  
Sbjct: 256 -HDEGAVNEEDDEG-KKKMALLDLLLRATVDG-KPLSDDDIREEVDTFTFAGHDTTASAL 312

Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374
           +F+L  +  + DVQ ++++E+  + G S    +     +++YL+ VI ESLRLYP VP+I
Sbjct: 313 TFLLFNIAKYSDVQQKLFEEISSVVG-STSELSLHTLNDLRYLDLVIKESLRLYPSVPMI 371

Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRH-YY 433
           AR    +  +   +  IP  T V +  F +HR P  ++DPE F P+ F       +H  +
Sbjct: 372 ARIATENTKLD--DMPIPKCTCVSVDIFQMHRDPDRFEDPESFIPERFDAIRDGGKHNAF 429

Query: 434 SYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAE 489
           +YIPFSAG R+C+G+K+A            + FR     P+ E  L+ +I+LK AE
Sbjct: 430 TYIPFSAGNRNCIGQKFAQYELKIAVVKLIQTFRLELPSPDIEPILKAEIVLKPAE 485


>UniRef50_Q16ML8 Cluster: Cytochrome P450; n=3; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 509

 Score =  232 bits (568), Expect = 1e-59
 Identities = 115/240 (47%), Positives = 156/240 (65%), Gaps = 3/240 (1%)

Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319
           D  ++   G KKRLAFLDL++E +     +++D +++EEVDT MFEGHDTT AG S+ L 
Sbjct: 273 DTGEDLYFGTKKRLAFLDLLLEGNAKH-KQLTDDDVREEVDTFMFEGHDTTTAGMSWALF 331

Query: 320 LLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLN 379
           LLG+H D Q RV+ E+  IF  SDRPAT  D  EMK LER + E+LRLYP V    RKL+
Sbjct: 332 LLGLHPDWQDRVHQEIDSIFAGSDRPATMKDLGEMKLLERCLKETLRLYPSVSFFGRKLS 391

Query: 380 RDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFS 439
            DVT+    Y IPAGT + I  + +HR  ++Y DPE F+PD FLPENT++RH ++YIPFS
Sbjct: 392 EDVTLG--QYHIPAGTLMGIHAYHVHRDERFYPDPEKFDPDRFLPENTEHRHPFAYIPFS 449

Query: 440 AGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
           AGPR+C+G+K+A            R FR  S     E K+  ++I +  EG ++ +E R+
Sbjct: 450 AGPRNCIGQKFAILEEKSIVSSVLRKFRVRSANTRDEQKICQELITRPNEGIRLYLEKRQ 509



 Score =  148 bits (358), Expect = 4e-34
 Identities = 69/190 (36%), Positives = 109/190 (57%), Gaps = 2/190 (1%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86
           + ++ R+W G +  + +   + +E I+ +  H++K+  Y F   WLGEGLL S G +W  
Sbjct: 71  YPDIHRIWTGMRPEIRISKPEYVETIIGASKHMEKSHGYDFLFDWLGEGLLTSKGERWFQ 130

Query: 87  HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETA 144
           HRK+I PTFH NIL  F  +F +    + E+L+  +  GK  DV  +++   +DI+ ETA
Sbjct: 131 HRKLITPTFHFNILDGFCDVFAEQGAVLAERLEPFANTGKPVDVFPFITKAALDIICETA 190

Query: 145 MGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGL 204
           MG+    Q     +Y  A+ +M +I   R  K W+  E +FK T + +Q  K L I+HG 
Sbjct: 191 MGVKVNAQTGGENNYVNAIYRMSEIFVDRSIKPWLHPEFIFKRTEYGRQHKKALDIVHGY 250

Query: 205 TNKVIKNKKE 214
           T KVI+++KE
Sbjct: 251 TKKVIRDRKE 260


>UniRef50_UPI00015B5014 Cluster: PREDICTED: similar to cytochrome
           P450 CYP4AB2; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis
          Length = 604

 Score =  229 bits (561), Expect = 1e-58
 Identities = 141/472 (29%), Positives = 248/472 (52%), Gaps = 21/472 (4%)

Query: 26  TFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWR 85
           T+  + + W     ++ +   DD+E+IL+S     K   Y++ + WL +GLL + G  +R
Sbjct: 144 TWYPICKGWAMGLPLLSVRHPDDLEVILSSQKACYKEFPYKYLRSWLNDGLLTNKGDTYR 203

Query: 86  SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTF--DVHDYMSGTTVDILLET 143
           + R+M+ P FH N+L+ +V I N+ S  ++ +L++  GK F  DV    +  +++I++E+
Sbjct: 204 ARRRMLTPAFHFNMLRRYVDIMNEQSGRLMTELRAN-GKEFVLDVLPIYADVSLNIIIES 262

Query: 144 AMGISRKTQDESGF-DYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202
           AMGI     D+    DY  A+  M  ++  R  + ++   ++   T   ++Q   L ++ 
Sbjct: 263 AMGIDLDKTDKKVIKDYKEAIEDMGIVLTYRMLRPYILDWMMTPFTEIGRKQIHALKVLR 322

Query: 203 GLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFN 262
             T+K+IK +++ +      GI     +EFT    + L N  +  S++++   +  L  +
Sbjct: 323 EFTDKIIKERRKYH--EMLGGI--KGYKEFT----DSLENQDE--SESIY--VKIQLMIH 370

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
                G KK+L  LD+++ + ++G   + +  IKEEVDT +  G DTT    ++   L+ 
Sbjct: 371 -HFFTGHKKKLPMLDILLSAEKDGL--LDEKGIKEEVDTFLLGGTDTTRMVMAYFTMLMA 427

Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382
            ++  Q +   E+ ++   S       +  +M YLE+ I ES+RLYP    I R    D+
Sbjct: 428 ENKKCQDKARAEVCKVLERSGGKRGMTELSQMPYLEQCIKESMRLYPIASTIFRHTVDDI 487

Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442
            +  KNY IPAG  V+      HR P ++ +PE F+PD FLPEN ++RH ++Y+PFSAGP
Sbjct: 488 QL--KNYTIPAGVVVICQIIDAHRDPNFWTEPEKFDPDRFLPENCRHRHPFAYLPFSAGP 545

Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMK 494
           R+C+G+K+              NF        ++ +L GD +L+ A+ F  K
Sbjct: 546 RNCIGQKFGWMEVKAVCSRLLYNFYLEPIDSTRDMQLIGDFVLRPADPFHTK 597


>UniRef50_UPI00015B561A Cluster: PREDICTED: similar to cytochrome
           P450 CYP4AB2; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis
          Length = 478

 Score =  221 bits (540), Expect = 3e-56
 Identities = 131/436 (30%), Positives = 222/436 (50%), Gaps = 33/436 (7%)

Query: 32  RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMI 91
           R+W  +  +V   D DD+ I+L    +I K   Y +F      GL+ S+G KW+  RK++
Sbjct: 39  RIWFFTCAVVITQDPDDLRILLTDKTNITKGFVYEYFHLMAKTGLITSTGEKWQYRRKIL 98

Query: 92  APTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFD-VHDYMSGTTVDILLETAMGISRK 150
            P FH +I+K ++ I  +     V+ +K++  +T   +    S  T+ I+LE AMGI  +
Sbjct: 99  TPAFHTHIIKKYMKITFEQGERFVKSIKAQGDETVQSLIPVCSDLTLSIILEAAMGIQFQ 158

Query: 151 TQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIK 210
           T      +Y  A+      I  R  + +++  ++     +F +  ++L  +     KV++
Sbjct: 159 TIGNKAEEYRKAIEHYFSSIAYRATRPYIKDWML----RYFSEGRRILATV-----KVLR 209

Query: 211 NKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEK 270
              +  ++ + +           +H         +T  ++  K   DD++    +  G K
Sbjct: 210 EFTDKIIDERRE-----------YHK--------QTKQESFQKYVDDDMEHECTDGEGRK 250

Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330
           KRLA LDL++ + + G   I +  IKEEVDT    G+DTT     ++L L+  ++D Q  
Sbjct: 251 KRLAMLDLLLMAEKEGL--IDEEGIKEEVDTFTAAGYDTTGMEMVYLLMLMAENKDQQEL 308

Query: 331 VYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYV 390
              E  +I   S    +  +  +M+Y+ER + ESLRL+P  P I R +  D+ +  KNY+
Sbjct: 309 ARAEANRILDASGGKISMKEINQMEYIERCVKESLRLFPTAPHIVRAVTEDIQL--KNYM 366

Query: 391 IPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKY 450
           +PAGT + +   +LHR PKY+ DP  F+PD FLP   + R+ ++Y+PFS GPR+C+G+K+
Sbjct: 367 VPAGTDIFVPIHILHRDPKYWSDPLKFDPDRFLPGEAEKRYPFTYLPFSHGPRNCIGQKF 426

Query: 451 AXXXXXXXXXXXXRNF 466
           A            RNF
Sbjct: 427 AIAELKSLLACVLRNF 442


>UniRef50_A0JMQ6 Cluster: Cytochrome P450, family 4, subfamily V,
           polypeptide 2; n=9; Coelomata|Rep: Cytochrome P450,
           family 4, subfamily V, polypeptide 2 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 513

 Score =  215 bits (525), Expect = 2e-54
 Identities = 99/245 (40%), Positives = 155/245 (63%), Gaps = 2/245 (0%)

Query: 255 YRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGS 314
           Y   ++ + E+D G +KR AFLD+++++       ++  +I+EEVDT MFEGHDTTAA  
Sbjct: 267 YLSYVESDSESDQGMRKRRAFLDMLLKTKDEDGKMLTHKDIQEEVDTFMFEGHDTTAAAM 326

Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374
           ++ + LLG H +VQ +   EL+++FG+S+RP    D  +++YLE VI ESLRL+P VP  
Sbjct: 327 NWAIHLLGSHPEVQRKAQQELFEVFGESERPVNTEDLKKLRYLECVIKESLRLFPSVPFF 386

Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434
           AR +  D  I+   + +P GT +V+ T+ LHR P+++ DPE F P+ FLPEN   RH Y+
Sbjct: 387 ARTICDDTQIN--GFKVPKGTNIVVITYALHRDPRFFPDPEEFRPERFLPENCVGRHPYA 444

Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMK 494
           YIPFSAG R+C+G+++A            R F  ++    +E +  G+++L+  +G  + 
Sbjct: 445 YIPFSAGLRNCIGQRFAIMEEKVILAYILRYFNIVACQKREELRPLGELVLRPEQGIWIT 504

Query: 495 VEPRK 499
           +E RK
Sbjct: 505 LERRK 509



 Score =  149 bits (362), Expect = 1e-34
 Identities = 74/207 (35%), Positives = 118/207 (57%), Gaps = 5/207 (2%)

Query: 21  LGYAQTFGN--VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLI 78
           +GY   F N  ++++W+G    + L  A+ +E +LN+ VHIDKA  Y+F  PWLG GLL 
Sbjct: 70  VGYTTEFQNSPLLKIWIGPIPFLILFHAETVETVLNNPVHIDKAYAYQFLHPWLGTGLLT 129

Query: 79  SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTV 137
           S+G KWR  RKM+ PTFH +IL  F+ + N+ +  ++EKL+ + GK  F+   +++   +
Sbjct: 130 STGDKWRRRRKMLTPTFHFSILTEFLEVMNEQAEVLIEKLEKQAGKGPFNCFSHITLCAL 189

Query: 138 DILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKL 197
           DI+ ETAMG     Q     +Y   V +M DII +R    W   + V+      ++  + 
Sbjct: 190 DIICETAMGKRIYAQSNYDSEYVRTVYRMSDIITRRQRMPWYWPDFVYNYVGEGREHNRS 249

Query: 198 LGIIHGLTNKVIKNKKE--TYLENKAK 222
           L I+H  T  VI  + E  +Y+E+ ++
Sbjct: 250 LKILHSFTESVINERAEYLSYVESDSE 276


>UniRef50_Q6ZWL3 Cluster: Cytochrome P450 4V2; n=83; Coelomata|Rep:
           Cytochrome P450 4V2 - Homo sapiens (Human)
          Length = 525

 Score =  214 bits (522), Expect = 5e-54
 Identities = 103/230 (44%), Positives = 149/230 (64%), Gaps = 2/230 (0%)

Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328
           + KR AFLDL++  + +  N++S  +I+EEVDT MFEGHDTTAA  ++ L LLG + +VQ
Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352

Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
            +V  EL  +FG SDRPAT  D  +++YLE VI E+LRL+P VP+ AR ++ D  ++   
Sbjct: 353 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 410

Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
           Y +  GT  VI  + LHR P+Y+ +PE F P+ F PEN Q RH Y+Y+PFSAGPR+C+G+
Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 470

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           K+A            R+F   S    +E  L+G +IL+ + G  +K++ R
Sbjct: 471 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRR 520



 Score =  140 bits (338), Expect = 1e-31
 Identities = 68/184 (36%), Positives = 113/184 (61%), Gaps = 1/184 (0%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           ++++W+G   +V L +A+++E+IL S   IDK++ Y+F +PWLG GLL S+G KWRS RK
Sbjct: 89  LLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRK 148

Query: 90  MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG-KTFDVHDYMSGTTVDILLETAMGIS 148
           M+ PTFH  IL+ F+ I N+ +N +V+KL+  +  + F+   Y++   +DI+ ETAMG +
Sbjct: 149 MLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKN 208

Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKV 208
              Q     +Y  AV +M ++I +R    W+  ++ + +     +  K L I+H  TN V
Sbjct: 209 IGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKILHTFTNSV 268

Query: 209 IKNK 212
           I  +
Sbjct: 269 IAER 272


>UniRef50_UPI0000D566B3 Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 511

 Score =  212 bits (518), Expect = 2e-53
 Identities = 104/247 (42%), Positives = 154/247 (62%), Gaps = 2/247 (0%)

Query: 256 RDDLDFNDEND--VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAG 313
           RD +    E D  +G+KKRLAFLDL++E+++N    ++D +I+EEVDT MF GHDT+   
Sbjct: 265 RDVVQELSEEDKLLGKKKRLAFLDLLLEANKNSEGGLTDEDIREEVDTFMFAGHDTSTVT 324

Query: 314 SSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPV 373
             + L  L  + + Q +V+ EL +IF   +RP T  D L+M+YL++VI E+ RL P VPV
Sbjct: 325 VGWTLFTLSNYPEYQEKVHQELDEIFQGEERPITPQDVLKMQYLDKVIKETQRLIPVVPV 384

Query: 374 IARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYY 433
           IAR L++D+ I   +  IPAG  VVI    LH+ P  + +P+ F+P+ FLPEN   RH Y
Sbjct: 385 IARTLDQDLEIVASSRTIPAGVMVVIHLARLHKDPDQFPEPDRFDPERFLPENVSKRHPY 444

Query: 434 SYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQM 493
           S++PFSAGPR+C+G+K+A            R ++  +E    E K   +I+L+   G  +
Sbjct: 445 SFVPFSAGPRNCLGQKFALRNTKVLLASILRKYKVRAEKKIDEMKYNIEIVLRPQGGLSV 504

Query: 494 KVEPRKR 500
            +EPR+R
Sbjct: 505 ALEPRRR 511



 Score =  138 bits (334), Expect = 3e-31
 Identities = 69/190 (36%), Positives = 110/190 (57%), Gaps = 2/190 (1%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSG-PKWR 85
           +G   R W+G    V ++  D +E IL+S V++ K   YRF  PWLGEGL+  S   KWR
Sbjct: 70  YGPFFRTWMGFIPAVHVMKPDHVERILSSTVNLTKGDNYRFVVPWLGEGLITGSNHKKWR 129

Query: 86  SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILLETA 144
            HRK+I PTFH +IL + + +  +    + E+L  +  G+ F+++ +++   +DI+ ETA
Sbjct: 130 VHRKLITPTFHFSILDNMMEVMAEKGQFLAEQLVPKANGQFFNIYPFLTLCELDIICETA 189

Query: 145 MGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGL 204
           MG+       S  +Y  +V  + DI+  R +  ++  + VF L+S  +Q  K L I+HG 
Sbjct: 190 MGVEVNAMKHSQSEYVRSVYGISDIMLYRMFHPYLHPDFVFNLSSKGRQHKKYLSILHGF 249

Query: 205 TNKVIKNKKE 214
           T KVI+ +KE
Sbjct: 250 TRKVIQERKE 259


>UniRef50_UPI00015B569D Cluster: PREDICTED: similar to cytochrome
           P450 CYP4C39; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4C39 - Nasonia vitripennis
          Length = 510

 Score =  210 bits (513), Expect = 7e-53
 Identities = 103/229 (44%), Positives = 146/229 (63%), Gaps = 4/229 (1%)

Query: 260 DFNDENDVGEKKR-LAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318
           D + E++ G K+R  AFLDL++E+S+N  N +S+ E++ EVDT MF GHDTTA   SF L
Sbjct: 271 DEDKEDEFGIKQRNKAFLDLLLEASENDKNPLSNDELRNEVDTFMFAGHDTTATAISFTL 330

Query: 319 CLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARK 377
            LLG H D+Q +V++EL  +F  D D+P   AD  ++KYL+RVI E+LRLYP  P   R 
Sbjct: 331 LLLGNHLDIQKKVHEELQTVFNNDVDKPTRAADLSQLKYLDRVIKETLRLYPSAPSFLRT 390

Query: 378 LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIP 437
           L  D       + I  G+ ++I  + +HR PK +++P VF+PD FLPEN ++RH Y+YIP
Sbjct: 391 LVEDTIFD--GHTICKGSVIIINAYDMHRDPKVWENPTVFDPDRFLPENVRSRHPYAYIP 448

Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486
           FSAGPR+C+G+K+A            R +R  S+   +  KL   IIL+
Sbjct: 449 FSAGPRNCIGQKFAMLELKIALTAILRKWRVKSDTLPENLKLLHSIILR 497



 Score =  116 bits (280), Expect = 1e-24
 Identities = 59/189 (31%), Positives = 101/189 (53%), Gaps = 4/189 (2%)

Query: 28  GNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSH 87
           GNV  +WLG +  V +     +E++L S V+I K++ Y    PWLG+GLL  +G KW  H
Sbjct: 71  GNVYIMWLGMQPYVNIQKPHHMEVLLTSTVNIKKSSIYNIIIPWLGDGLLTLTGKKWHHH 130

Query: 88  RKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG----KTFDVHDYMSGTTVDILLET 143
           R+++ P FH  +L+ F    ++ ++   E LK +V     +  D+  + S  T+D++ +T
Sbjct: 131 RRLLTPAFHFRVLEQFTETMHEKADVFNECLKEQVSSNPKEPVDIFSFASRFTLDVICKT 190

Query: 144 AMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHG 203
           AMGI    Q  S   Y  +V +M   +  R+ + W  S+ ++  T   KQ    + ++  
Sbjct: 191 AMGIDMDAQRGSMNLYTKSVNQMSRFVVNRYLRPWYASDFIYSKTEDGKQSQAAISVMRE 250

Query: 204 LTNKVIKNK 212
            ++KVIK +
Sbjct: 251 YSSKVIKER 259


>UniRef50_Q964T1 Cluster: Cytochrome P450 4c21; n=1; Blattella
           germanica|Rep: Cytochrome P450 4c21 - Blattella
           germanica (German cockroach)
          Length = 501

 Score =  203 bits (495), Expect = 1e-50
 Identities = 101/239 (42%), Positives = 151/239 (63%), Gaps = 7/239 (2%)

Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321
           +++ D+G+KKR+ FLD ++++S++  NK++D +I EEV T MFEGHDT +A  +++L  L
Sbjct: 267 SEDADIGKKKRVPFLDTLLDASEDD-NKLTDTDILEEVHTFMFEGHDTVSAAMTWLLFEL 325

Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381
           G H ++Q   Y E+  IF  SDR  T AD   M YLERVI ESLRL+P V    R+ ++D
Sbjct: 326 GHHPEIQEEAYKEVQDIFQGSDRVPTMADLNNMNYLERVIKESLRLHPSVIYFVREAHQD 385

Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441
             +    Y IPAGT +      +HR P+ + +P  FNPDNFLP+   NRH Y+YIPFSAG
Sbjct: 386 FELG--GYTIPAGTNIDFSVPFIHRNPEIFPNPRCFNPDNFLPDRVVNRHPYAYIPFSAG 443

Query: 442 PRSCVGRKYAXXXXXXXXXXXXRN--FRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           PR+C+G+++A            R+  FRT+++  + +FKL  ++I    +  Q+ +E R
Sbjct: 444 PRNCIGQRFALLEEKVVLSYLLRHYRFRTVNKREDSKFKL--EMINTPVKPIQLIIEAR 500



 Score =  153 bits (371), Expect = 1e-35
 Identities = 76/188 (40%), Positives = 112/188 (59%), Gaps = 1/188 (0%)

Query: 34  WLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAP 93
           + G++  V +   + IE++L +   IDKA  Y  F  WLG GLL SSG KW  HRK+I P
Sbjct: 75  YFGNRPFVNISSPELIEVVLRNTQLIDKAFLYDLFHSWLGTGLLTSSGAKWHQHRKIITP 134

Query: 94  TFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRKTQ 152
           TFH +IL+ F+ IF + S  +V KL+ EVG+  F +  Y+S   +DI+ ETAMG S   Q
Sbjct: 135 TFHFSILEGFITIFAEKSEILVRKLQKEVGRGPFFIRQYVSNCALDIICETAMGTSVNAQ 194

Query: 153 DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNK 212
           DE   +Y  A+ KM D++  R     +  E +FKLT ++    K L +++G  NK+I+ +
Sbjct: 195 DEGFSEYVTAINKMTDVLSDRMANPLLYPEFIFKLTPYYWTHKKCLKVLNGFVNKIIQER 254

Query: 213 KETYLENK 220
           KE   ++K
Sbjct: 255 KEERKKSK 262


>UniRef50_Q7YSZ3 Cluster: P450 enzyme precursor; n=1; Rhodnius
           prolixus|Rep: P450 enzyme precursor - Rhodnius prolixus
           (Triatomid bug)
          Length = 512

 Score =  202 bits (493), Expect = 2e-50
 Identities = 106/270 (39%), Positives = 161/270 (59%), Gaps = 7/270 (2%)

Query: 231 EFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKI 290
           ++ H+  E +  N K L   + K Y ++ +  ++N+ G+ K+ AFL+++I+        +
Sbjct: 247 KYLHNFSENIIQNRK-LKYLLEKKYSEN-NIEEDNNFGKGKK-AFLNILIDLEDKSKGTL 303

Query: 291 SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFAD 350
           +D +I+EEVD  MF GHDTTA+   F L LLG H  VQ + ++ELY+IFG+SDR     D
Sbjct: 304 TDKDIREEVDNFMFAGHDTTASCIMFTLYLLGRHPHVQEKAFEELYEIFGESDREVNNKD 363

Query: 351 TLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKY 410
              M YLE +I ES+R+YPP P  +R L +D+ +  K  V+P G  V I  F++HR PKY
Sbjct: 364 LHGMHYLEMIIKESIRIYPPAPYFSRNLIQDLVLKDKT-VLPEGANVGIFAFIMHRDPKY 422

Query: 411 YKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTIS 470
           + +PEVF+P+ F  EN + RH Y+Y+PFSAGPR+C+G+K+A            R F  I 
Sbjct: 423 FPNPEVFDPERFSAENCKKRHPYAYLPFSAGPRNCIGQKFAMMELKVVLSTILR-FAKIE 481

Query: 471 EIPEK--EFKLQGDIILKRAEGFQMKVEPR 498
            + ++     L   I+LK  +  ++KV  R
Sbjct: 482 SVNDEISARSLTPLILLKPCDPIRIKVFSR 511



 Score =  123 bits (297), Expect = 1e-26
 Identities = 62/197 (31%), Positives = 105/197 (53%), Gaps = 1/197 (0%)

Query: 25  QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKW 84
           Q +  ++  WL     V+L D DD+E+IL S   I K  EY    PW+ +GL++S G KW
Sbjct: 72  QEYARLVAFWLAGIPTVWLFDPDDLEVILASSQAIQKGNEYHCLFPWMQDGLVLSKGEKW 131

Query: 85  RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETA 144
              RK++ P FH  IL++ +   N+N+  ++  +  + G+ F   + +   T+D++ ETA
Sbjct: 132 HQRRKLLTPAFHFKILENNMQSLNKNARCLLRNMLKKEGRPFVTQELVVRCTLDVISETA 191

Query: 145 MGISRKTQD-ESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHG 203
           MG +   Q+ E   DY  AV + C +   R    +  ++ V+ LT   ++ +K L  +H 
Sbjct: 192 MGHALNLQEREENNDYLNAVERACSLTFDRSKNVFYSNDGVYFLTLDGRKFSKNLKYLHN 251

Query: 204 LTNKVIKNKKETYLENK 220
            +  +I+N+K  YL  K
Sbjct: 252 FSENIIQNRKLKYLLEK 268


>UniRef50_Q9VVN6 Cluster: Probable cytochrome P450 312a1; n=2;
           Sophophora|Rep: Probable cytochrome P450 312a1 -
           Drosophila melanogaster (Fruit fly)
          Length = 510

 Score =  202 bits (493), Expect = 2e-50
 Identities = 134/457 (29%), Positives = 227/457 (49%), Gaps = 40/457 (8%)

Query: 32  RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMI 91
           ++W+G+KL +   +  DI+ + ++   + K  +YR F+ WL EGL  S   KW   RK++
Sbjct: 75  KLWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFENWLCEGLFTSGFEKWSHRRKIV 134

Query: 92  APTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGISR 149
            P F+  ++K FV +F + S  ++  +   +E G   D    +S  T+D + ETA+G+S 
Sbjct: 135 MPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALGVSV 194

Query: 150 KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVI 209
            +Q  +  +Y  AV  +  II +R    + R+  +FK TS +K++ +L           I
Sbjct: 195 GSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQEL-----------I 243

Query: 210 KNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGE 269
           K      L    +GII   ++E    +     N     SD        +LD       G 
Sbjct: 244 KT-----LHGFTEGIIQKRIDEINQDA----ENRNYQSSDA-------ELD-------GV 280

Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329
           K+ L FLD ++ S       ++  +I+EEVDTI+F G D TA   +F +  + +H + Q 
Sbjct: 281 KRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQ 340

Query: 330 RVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
           R  +E++ + G D   P +     ++++LE  I E+LR+YP  P+ ARK   + TI+  +
Sbjct: 341 RCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTIN--D 398

Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
           + IP G+ V+I    + R   ++ DP VF PD +           ++IPF AG RSC+G+
Sbjct: 399 FFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFIPFMAGARSCMGQ 458

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIIL 485
           +YA            RNF     + E++ KL+ + ++
Sbjct: 459 RYAMVMLKMVLAHLLRNF-LFEPLGERQVKLKLNFVI 494


>UniRef50_UPI0000E46807 Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily v; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to cytochrome P450,
           family 4, subfamily v - Strongylocentrotus purpuratus
          Length = 487

 Score =  201 bits (491), Expect = 3e-50
 Identities = 102/243 (41%), Positives = 152/243 (62%), Gaps = 5/243 (2%)

Query: 259 LDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318
           +D ND ND G K+R+AFLDL+++  ++  +  +  +I+EEVDT MFEGHDTTAA +S+ +
Sbjct: 211 VDSND-ND-GSKRRIAFLDLLLKMQRDDPS-FTKSDIREEVDTFMFEGHDTTAALASWAM 267

Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKL 378
            L+G H  VQ +++ EL  +FGDSDRP T  D  ++ YL  V+ E+LR++P VP++ R L
Sbjct: 268 FLIGHHTRVQKKLHQELDSVFGDSDRPVTADDLQKLPYLTCVLKETLRIFPSVPIVGRDL 327

Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPF 438
             D  I  K  + P GT ++I    LHR P  + +P +F+PD FLPE +  RH +SY+PF
Sbjct: 328 QEDCIIDGK--LAPRGTLLIIAIGSLHRDPTQFPEPLMFDPDRFLPEFSSKRHPFSYVPF 385

Query: 439 SAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           SAGPR+C+G+++A            R F   S    K+     ++IL+ +EG  MK+  R
Sbjct: 386 SAGPRNCIGQRFALMEDKVLLANVLRCFSLESTQSLKDTMPIAELILRPSEGIHMKITRR 445

Query: 499 KRV 501
           K +
Sbjct: 446 KGI 448



 Score = 97.9 bits (233), Expect = 6e-19
 Identities = 55/145 (37%), Positives = 81/145 (55%), Gaps = 4/145 (2%)

Query: 74  EGLL-ISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT--FDVHD 130
           +GL+ + +G KW   RKM+ PTFH  IL +F+ +F++ SN + +K      K    ++  
Sbjct: 73  KGLMRLCTGKKWFHRRKMLTPTFHFAILHNFIEVFDEQSNTLCQKFGEHAQKQDLVNICP 132

Query: 131 YMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSF 190
            ++   +DI+ ETAMG     QDES  DY  AVM+M DII QR  K W   + +F  T  
Sbjct: 133 LVTLCVLDIISETAMGKQLHAQDESNNDYVNAVMRMSDIIQQRQKKPWFWPDPLFDNTKS 192

Query: 191 FKQQTKLLGIIHGLTN-KVIKNKKE 214
            K+  + L I+H +TN KV  N  +
Sbjct: 193 GKEHAQCLQILHKMTNTKVDSNDND 217


>UniRef50_Q9NGQ5 Cluster: Insecticide resistance-associated
           cytochrome P450; n=2; Cucujiformia|Rep: Insecticide
           resistance-associated cytochrome P450 - Diabrotica
           virgifera virgifera (western corn rootworm)
          Length = 501

 Score =  196 bits (478), Expect = 1e-48
 Identities = 91/230 (39%), Positives = 144/230 (62%), Gaps = 3/230 (1%)

Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328
           ++K+LAFLDL++ +  +    I D  IK+EV+T MFEGHDTTA G S++L  L  H + Q
Sbjct: 273 KRKKLAFLDLLLNAKLS-KGIIDDQGIKDEVNTFMFEGHDTTATGISWILRQLATHSEYQ 331

Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
            ++Y+E+  + GD+ +     D  E+K +ER I E+LRL+PPVP IAR L+ D+ ++   
Sbjct: 332 DQIYEEIITVLGDAQKQPDLNDLNELKVMERFIKETLRLFPPVPYIARTLDEDIELN--G 389

Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
           Y+IP   ++ I  + +HR PK++ +PE F+PD FLPEN  NRH ++Y+PFSAGPR+C+G+
Sbjct: 390 YLIPKEASIDIWIYDIHRNPKHWPEPEKFDPDRFLPENCVNRHPFAYVPFSAGPRNCIGQ 449

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           ++A            +NF        ++ ++  D++L+ A    +   PR
Sbjct: 450 RFAMYEMKAIICGIMQNFSVKLADKNEKVEIMTDLVLRSAHEINLNFIPR 499



 Score =  103 bits (247), Expect = 1e-20
 Identities = 54/179 (30%), Positives = 95/179 (53%), Gaps = 2/179 (1%)

Query: 40  IVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 99
           +V +   D+ E I +   HI K   Y   +PWLG+GLL +SG  W+  RK++ P FH +I
Sbjct: 83  VVVVTGPDEFEKIASGSKHITKGMIYGLVEPWLGKGLLTNSGSLWQQRRKILTPAFHFSI 142

Query: 100 LKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHDYMSGTTVDILLETAMGISRKTQDESGFD 158
           L+ FV +FN+ +  +VE +K E  K+  ++   +S T ++ + ET+ G +     +   +
Sbjct: 143 LQEFVKVFNKETARLVETIKQENKKSATNIIPLISQTALNTIAETSFGTTLDLTKKDDKN 202

Query: 159 YAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTK-LLGIIHGLTNKVIKNKKETY 216
           Y  A+ +M  I+  R  + W  S  VF + S    + K +L  +H  T ++I  + + +
Sbjct: 203 YVSAIHEMGKILIYRMVRPWFYSLFVFYILSSVGAKLKQVLSTLHSFTERIIPERSKDF 261


>UniRef50_A6Y7S1 Cluster: Female neotenic-specific protein 4; n=1;
           Cryptotermes secundus|Rep: Female neotenic-specific
           protein 4 - Cryptotermes secundus
          Length = 271

 Score =  196 bits (477), Expect = 2e-48
 Identities = 94/203 (46%), Positives = 126/203 (62%), Gaps = 3/203 (1%)

Query: 265 NDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324
           +D G + R+  LD++IE S+N  +     +++EE+  ++   ++TTA   SF   +L  H
Sbjct: 62  HDKGRRARIPILDMLIELSRNDKD-YGRLDVREEIAAMLIVSYETTAVALSFACWMLSQH 120

Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384
           QDVQ +V  E  +IFGDSDRPAT+ D  EMKYLE VI E++RLYP +PV  RKL RD  +
Sbjct: 121 QDVQEKVLMEQKEIFGDSDRPATYRDIQEMKYLEMVIRETIRLYPSLPVFGRKLQRDFDV 180

Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRS 444
              ++VIPAG  V+   + +HR PKY+ DPE FNPD FLP+N   R  Y Y+ FSAGPR+
Sbjct: 181 G--DFVIPAGANVMFLAYQIHRNPKYFPDPEKFNPDRFLPDNVMRRSPYCYLAFSAGPRN 238

Query: 445 CVGRKYAXXXXXXXXXXXXRNFR 467
           CVG KY             R FR
Sbjct: 239 CVGIKYGMQAIKGTLSAMIRKFR 261


>UniRef50_Q695H3 Cluster: Pheromone-degrading enzyme; n=2;
           Phyllopertha diversa|Rep: Pheromone-degrading enzyme -
           Phyllopertha diversa (Pale-brown chafer beetle)
          Length = 502

 Score =  195 bits (476), Expect = 2e-48
 Identities = 96/232 (41%), Positives = 144/232 (62%), Gaps = 4/232 (1%)

Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327
           G KK+ AFLDL++E S N  +    H I+EEVDT MFEGHDTTA   +F L  L ++  +
Sbjct: 271 GRKKKQAFLDLLLEYSANDPSFTEQH-IQEEVDTFMFEGHDTTATSITFALYALAMNPHI 329

Query: 328 QARVYDELYQIFGD-SDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386
           Q + Y EL +IF + S R A++ D  EMKYLE VI E+LR+Y  VP  +R L  DV ++ 
Sbjct: 330 QEKAYAELKEIFSNNSKRHASYRDLQEMKYLEMVIKETLRIYTTVPFYSRALEEDVNMNG 389

Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446
           +  ++P GT + +  + +H  PK YKDPE F+P+ F  EN++ R  +++IPFSAGPR+C+
Sbjct: 390 Q--ILPKGTMLNVFAYGVHHNPKIYKDPETFDPERFSIENSKERSPFAFIPFSAGPRNCI 447

Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           G+K+A            RNF+ +  +P  +  L+ + +LK   G  ++++ R
Sbjct: 448 GQKFAMLEMKSSISDVLRNFKLLPSVPAHKVVLKSEAVLKSDNGVFVRLQKR 499



 Score =  144 bits (349), Expect = 5e-33
 Identities = 69/193 (35%), Positives = 118/193 (61%), Gaps = 2/193 (1%)

Query: 28  GNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSH 87
           GN  ++++G++  VFLV+  D+E +LNS   + K+  Y+F   WLG GLL SSG KW+ H
Sbjct: 68  GN-FKLYIGAQPRVFLVEPKDLEFLLNSTSLLTKSKSYKFLYRWLGAGLLTSSGNKWKKH 126

Query: 88  RKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMG 146
           RK+I P FH  IL+ F+ +FN  S+ +VEKL +   K + D++ +++  T+DI+ ETAMG
Sbjct: 127 RKIITPAFHFQILEEFIDVFNSASDVLVEKLNAAPNKSSIDIYPFIARCTLDIICETAMG 186

Query: 147 ISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTN 206
            S   Q++   +Y  +V  +  I+ QR     + +++++  T+ ++++   L ++HG T 
Sbjct: 187 TSVDAQNDINSEYVNSVKILLGILVQRSLSPILANDLLYPFTTTYQKEKAALKVVHGYTK 246

Query: 207 KVIKNKKETYLEN 219
            VI  +K  +  N
Sbjct: 247 SVINKRKIEFYNN 259


>UniRef50_O76478 Cluster: Corpora allata cytochrome P450; n=2;
           Neoptera|Rep: Corpora allata cytochrome P450 -
           Diploptera punctata (Pacific beetle cockroach)
          Length = 497

 Score =  195 bits (476), Expect = 2e-48
 Identities = 92/242 (38%), Positives = 152/242 (62%), Gaps = 4/242 (1%)

Query: 258 DLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFV 317
           +++ + +N + +K RLA LDL++E S+NG   ++D +I EEVDT MF GHDT A+G S++
Sbjct: 258 EVEISQQNGIKKKHRLALLDLLLELSENG-KVLTDEDICEEVDTFMFAGHDTIASGVSWI 316

Query: 318 LCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIAR 376
           L +LG H D Q ++ +E   +   D+    T     ++ YLER I E++RLYP VP+IAR
Sbjct: 317 LYVLGHHLDSQEKIVEEFKNVMEEDNTEWPTMKHLNKLCYLERCIKEAMRLYPVVPLIAR 376

Query: 377 KLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYI 436
            L + + I   +Y++P G T++I T++LHR  +++ +P++F PD FL  N + R+ ++Y+
Sbjct: 377 NLTQPIKIM--DYMLPEGVTILINTYLLHRDSRFFPNPDIFEPDRFLTSNCEARNPFAYV 434

Query: 437 PFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496
           PFSAGPR+C+G+K+A            + F   S   E+  KL G+++L   +G ++ + 
Sbjct: 435 PFSAGPRNCIGQKFAMMELKIILSTVLQRFIVKSVDKEERLKLVGELVLLNRDGIRLTIT 494

Query: 497 PR 498
            R
Sbjct: 495 AR 496



 Score =  155 bits (376), Expect = 3e-36
 Identities = 76/195 (38%), Positives = 117/195 (60%), Gaps = 1/195 (0%)

Query: 24  AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK 83
           A  +GN+ R+W+G +  VFL  A+ I+ ILNS V+IDK+ EY F  PWLG GLL S+G K
Sbjct: 58  ATKYGNIFRLWVGQRPFVFLYSAEAIQPILNSTVYIDKSYEYSFLFPWLGTGLLTSTGNK 117

Query: 84  WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHDYMSGTTVDILLE 142
           W + RK++  +FH  +L+ F+    Q+S  +  +L+ E+ K  F V  Y     +DI+ +
Sbjct: 118 WHTRRKLLTQSFHSKVLEDFLEPIYQHSLFLCNRLELELDKPHFKVTPYAKLCALDIICD 177

Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202
           TAMG +   Q+ S  +Y  AV  + +I+ +R    W++ + +FK+T   K+Q + L I+H
Sbjct: 178 TAMGSTINAQENSQSEYVTAVDSLSEIVQRRFITPWLKPDFLFKMTKLGKKQEQCLKIVH 237

Query: 203 GLTNKVIKNKKETYL 217
             T KVI  +KE  L
Sbjct: 238 NFTRKVINERKEDKL 252


>UniRef50_A1BPS2 Cluster: CYP4BF1; n=2; Ips paraconfusus|Rep:
           CYP4BF1 - Ips paraconfusus
          Length = 511

 Score =  195 bits (475), Expect = 3e-48
 Identities = 106/270 (39%), Positives = 154/270 (57%), Gaps = 7/270 (2%)

Query: 229 LEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTN 288
           L+  T  +  ++A   K L  T  K  +++    +E  +G K R AFLDL++     G  
Sbjct: 245 LKLVTDFTQNVIAERRKELH-TAKKTVQENKSGTEE--IGGKTRRAFLDLLLSIQDEG-- 299

Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATF 348
           K++D +I+EEVDT MFEGHDTT++G S+ +  L  H D Q +V  E+  +FG+SDR  T 
Sbjct: 300 KLTDEDIREEVDTFMFEGHDTTSSGMSWTIWCLAHHLDYQNKVIQEIDAVFGNSDRNCTN 359

Query: 349 ADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQP 408
            D  E+KYLE+ I E++RLYPPVP+I+RK+  D       Y +P   T++I   +LHR P
Sbjct: 360 EDLKELKYLEQCIKEAMRLYPPVPLISRKVEED--FHCAGYDVPRDATILISPLVLHRDP 417

Query: 409 KYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRT 468
             Y++ E +NP+NF P     RH YS+IPFSAGPR+C+G+K+A            R +  
Sbjct: 418 ALYENVESYNPENFSPSAIARRHAYSFIPFSAGPRNCIGQKFALMEERTVLSWFFRRYCV 477

Query: 469 ISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
            S            IILK ++G  +K+  R
Sbjct: 478 RSSEEFLSNIPCAKIILKPSKGVPIKIYRR 507



 Score =  101 bits (241), Expect = 6e-20
 Identities = 57/196 (29%), Positives = 101/196 (51%), Gaps = 7/196 (3%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           V+R WLG   IV     + ++ +L S+  I K  EY   + WLG GLLIS+G KWRS RK
Sbjct: 75  VVRFWLGPIPIVCAFGPESVKTVLESNKVITKGDEYDILERWLGTGLLISTGNKWRSRRK 134

Query: 90  MIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGI 147
           M+   FH N+L  F+  +++ +   +++++  ++  + FDV  ++    +DI+ ET+M  
Sbjct: 135 MLTMAFHFNVLNGFMDTYDKEARIFLDQIREFADTNEPFDVCPFIKRCALDIICETSMAH 194

Query: 148 SRKTQDESGFDY--AMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205
               Q +    Y  A+A M     ++ R   FW++   +++     +   + L ++   T
Sbjct: 195 KIDAQVDHNHPYVNAVAQMNTLSFLYARSPWFWIKP--IWRFFGHEENYERNLKLVTDFT 252

Query: 206 NKVI-KNKKETYLENK 220
             VI + +KE +   K
Sbjct: 253 QNVIAERRKELHTAKK 268


>UniRef50_UPI0000E46144 Cluster: PREDICTED: similar to
           ENSANGP00000019301; n=5; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to ENSANGP00000019301
           - Strongylocentrotus purpuratus
          Length = 469

 Score =  192 bits (468), Expect = 2e-47
 Identities = 89/187 (47%), Positives = 128/187 (68%), Gaps = 3/187 (1%)

Query: 261 FNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCL 320
           + D+    ++KR+AFLDL+++  +      +   I+EEVDT MFEGHDTTAA  ++ L L
Sbjct: 272 YEDDAVTRKRKRIAFLDLLLQMHREDAT-FTLEAIREEVDTFMFEGHDTTAAAVNWALLL 330

Query: 321 LGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380
           +G H  VQAR++DE+ Q+FGDS+RP T  D  E+ YL  V+ ESLRL P VP I R L+ 
Sbjct: 331 IGQHPTVQARLHDEIDQVFGDSERPITSDDLSELSYLSCVVKESLRLLPSVPGIGRDLDE 390

Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440
           D+ ++ K  V+P G +V +  + +H  P+ + DPE F+PD FLPEN+  RH +++IPFSA
Sbjct: 391 DIIVNGK--VVPKGASVFLSIYGIHHDPEQFPDPERFDPDRFLPENSTKRHPFAFIPFSA 448

Query: 441 GPRSCVG 447
           GPR+C+G
Sbjct: 449 GPRNCIG 455



 Score =  138 bits (333), Expect = 4e-31
 Identities = 69/184 (37%), Positives = 107/184 (58%), Gaps = 2/184 (1%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82
           Y    G VIR+W G   IV + +A   E ++NS  HI+K TEY F +PWLG+GLL S G 
Sbjct: 72  YRHQSGGVIRMWFGPLPIVLIYNAVHCEALMNSSRHINKGTEYTFMEPWLGKGLLTSGGQ 131

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDIL 140
           KW   RK++ PTFH +IL+SF+ +FN+ S  +V+KL   ++  +T ++   ++   +DI+
Sbjct: 132 KWFHRRKLLTPTFHFSILQSFMEVFNEQSMILVKKLGKFADESETVNIFPLVTHCVLDII 191

Query: 141 LETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGI 200
            +TAMG     Q ++  +Y  AV +M  +I  R   F +  + ++  T   K   K L I
Sbjct: 192 CDTAMGKRTNAQSDNENEYVKAVGRMSHLIVSRIRNFMLWPDWIYNRTDAGKDHEKALQI 251

Query: 201 IHGL 204
           +HG+
Sbjct: 252 LHGM 255


>UniRef50_Q27472 Cluster: Cytochrome p450 family protein 32A1; n=3;
           Bilateria|Rep: Cytochrome p450 family protein 32A1 -
           Caenorhabditis elegans
          Length = 529

 Score =  192 bits (468), Expect = 2e-47
 Identities = 97/248 (39%), Positives = 150/248 (60%), Gaps = 5/248 (2%)

Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSS 315
           R +L   D N+  EKKR AFLDL++ + Q     +SD +I+EEVDT MFEGHDTT++G  
Sbjct: 276 RKELLNEDGNEASEKKRKAFLDLLL-TIQKEEGTLSDEDIREEVDTFMFEGHDTTSSGIG 334

Query: 316 FVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374
           F +  LG + + Q ++  EL ++FG ++++P +  D  +  YLE+ I ESLR++P VP+I
Sbjct: 335 FTILWLGFYPECQKKLQKELDEVFGFETNQPPSMDDIKKCSYLEKCIKESLRMFPSVPLI 394

Query: 375 ARKLNRDVTI---STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRH 431
           AR+L+ DVTI   S +  V+PAG    +      R P+ + DP+ +NPDNF  +    R 
Sbjct: 395 ARRLSEDVTINHPSGQKIVLPAGLAACVSPIAAARDPRAWPDPDTYNPDNFDIDAIAGRD 454

Query: 432 YYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGF 491
            Y+YIPFSAGPR+C+G+K+A            R +   S   E+  +   ++IL+   G 
Sbjct: 455 PYAYIPFSAGPRNCIGQKFALLEQKTILSTFFRKYEVESLQTEENLRPVPELILRPYNGM 514

Query: 492 QMKVEPRK 499
           ++K++ R+
Sbjct: 515 KIKIKRRE 522



 Score =  111 bits (266), Expect = 6e-23
 Identities = 61/192 (31%), Positives = 104/192 (54%), Gaps = 3/192 (1%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           ++ +W+G   IVFL  ++ I  +L S+ +I K ++Y     W+G GLL S+  KW   RK
Sbjct: 93  IMLLWIGPVPIVFLGTSECIRPVLESNTNISKPSQYDKMSEWIGTGLLTSTHEKWFHRRK 152

Query: 90  MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILLETAMGIS 148
           M+ PTFH  I++ +  +F +N+  + + ++  V G  FD   Y    T+DI+ ETAMGI 
Sbjct: 153 MLTPTFHFTIIQDYFPVFVRNAEVLADAVELHVDGDYFDAFPYFKRCTLDIICETAMGIQ 212

Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKF-WMRSEIVFKLTSFFKQQTKLLGIIHGLTNK 207
              Q     +Y  AV ++ +I+   H KF W+  + ++ LT    +  + + + +    K
Sbjct: 213 VNAQLGHNNEYVHAVKRISEIV-WNHMKFPWLWLKPIWYLTGLGFEFDRNVRMTNNFVRK 271

Query: 208 VIKNKKETYLEN 219
           VI+ +KE   E+
Sbjct: 272 VIQERKELLNED 283


>UniRef50_UPI0000D55952 Cluster: PREDICTED: similar to Cytochrome
           P450 4d2 (CYPIVD2); n=2; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4d2 (CYPIVD2) -
           Tribolium castaneum
          Length = 501

 Score =  191 bits (465), Expect = 4e-47
 Identities = 102/243 (41%), Positives = 142/243 (58%), Gaps = 8/243 (3%)

Query: 252 FKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTA 311
           FK  +D+   ++E   G K+R A LD+++E S NG N ++D +I+EEVDT MFEGHDTT 
Sbjct: 260 FKLLQDNAKISEE---GIKRRAALLDMLLEVSDNGKN-LTDEDIREEVDTFMFEGHDTTT 315

Query: 312 AGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPP 370
               FVL  +  + DVQ ++YDEL  + G D  +  TF+D  E+KYL+ VI E+ RLYPP
Sbjct: 316 TSICFVLYAIAQNPDVQKKIYDELVSVLGPDCKKEITFSDIQELKYLDVVIKEAHRLYPP 375

Query: 371 VPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNR 430
           VP+I R L  D TI      IP  T + I  + ++     Y +P VF+PD FLPE    R
Sbjct: 376 VPLIERSLEEDCTID--GLTIPKNTNISIFLYGMNYNKDVYPEPHVFDPDRFLPEKQGER 433

Query: 431 HYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEG 490
           H ++Y+PFSAGPR+C+G+K+A            R F  IS  P+   ++    +LK   G
Sbjct: 434 HTFAYVPFSAGPRNCIGQKFALLELKTTIAKLLRCFE-ISPDPKNPPQVGMCSVLKSRNG 492

Query: 491 FQM 493
             M
Sbjct: 493 IHM 495



 Score =  156 bits (379), Expect = 1e-36
 Identities = 76/216 (35%), Positives = 128/216 (59%), Gaps = 6/216 (2%)

Query: 13  TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72
           T  L++  +     +G V++VWLG +L + +   + +E  LNS VH++K+  Y  FKPWL
Sbjct: 53  TVDLLHSFMNLQDKYGTVVKVWLGPRLHLLITKPEMVEFFLNSTVHLNKSDGYDLFKPWL 112

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI-FNQNSN---NVVEKLKSEVGKTFDV 128
           G+GLL+S+G KW++ RK+I PTFH  IL++F+   FN+  N   +V+ K  S+  K+ ++
Sbjct: 113 GDGLLVSTGSKWKTRRKLITPTFHFKILENFLETSFNKQINILLDVLLKEASQTDKSIEI 172

Query: 129 HDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLT 188
           H  ++  ++DI+ ETA G     Q +    Y  AV    +I   R +  W+R  ++F+L+
Sbjct: 173 HSLINLCSLDIICETAFGTELNAQAKCNPKYVEAVTGFLEIFTLRFFSAWLRHPLIFRLS 232

Query: 189 SFFKQQTKLLGIIHGLTNKVIKNKKETY--LENKAK 222
             + +  + L I+H  TN +IK +KE +  L++ AK
Sbjct: 233 DKYAKYMEYLKILHDFTNTIIKRRKEEFKLLQDNAK 268


>UniRef50_UPI00015B560A Cluster: PREDICTED: similar to cytochrome
           P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 543

 Score =  188 bits (458), Expect = 3e-46
 Identities = 136/498 (27%), Positives = 239/498 (47%), Gaps = 31/498 (6%)

Query: 13  TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72
           T+ +++       T+ +  RVWL  +L   + D + ++ I  S   I+K   Y+F +PWL
Sbjct: 57  TEDILSKCQELLDTYPSPFRVWLADRLFYAVYDPEQLKTIFLSPKTIEKEELYKFAEPWL 116

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDY 131
           G GL  +   KWR HRK+I PTF+  IL+SFV +F+  S  ++++++ E+ G  FD+  Y
Sbjct: 117 GTGLFTAPASKWRIHRKLIMPTFNPRILESFVEVFSVQSEVMIKEMEVELNGGEFDIFHY 176

Query: 132 MSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFF 191
           +S  T+DI+ ETAMG+  + Q +    Y  +  ++ +I++ R +K W+  +I+F  T   
Sbjct: 177 VSLCTLDIICETAMGVRSRAQTQRNSPYVESAKRLFEIVYSRMFKIWLHPDIIFNNTRLG 236

Query: 192 KQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTV 251
           K Q + +  +H LT+ VIK KK+ +  N        T+E       ++     K   D +
Sbjct: 237 KDQRECIKYVHSLTDDVIKRKKQAFEGN-------GTVEGMNGKLPQV-EGKRKAFLDLL 288

Query: 252 FKGYRDDLDFNDE--NDVGEKKRLAFLDLMIESSQNGTNKISDH-EIKEEVDTIMFEGHD 308
            +   +   F DE   +  +   +A  D     +      ++ H EI+++V   + E + 
Sbjct: 289 MELSHEGTKFTDEELREEVDTMMIAGNDTTATVNCFVMLMLASHPEIQDKVYEELCEIY- 347

Query: 309 TTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLY 368
               GS     +L  H+D+    Y  L ++  ++ R       L  +  + + + +  LY
Sbjct: 348 ----GSEDPSSVLVRHEDLHRMEY--LERVIKETMRIFPVGPVLVRRVTDDLNIGNHPLY 401

Query: 369 PPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVF-NPDNF----- 422
             +       N D       Y I    T+  G+ ++    K ++  E + +P  F     
Sbjct: 402 FAI----MNCNFDYINQICFYGITGDYTLTKGSSVVLGIIKTHRSEEYWTDPLTFNPDRF 457

Query: 423 LPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF--RTISEIPEKEFKLQ 480
           LPE    RH Y+YIPFSAGPR+C+G KYA            R +  +  + +P ++ KL+
Sbjct: 458 LPEECAKRHPYTYIPFSAGPRNCLGMKYAMMAMKALLATVIRKYVIKKDNALPVQDIKLK 517

Query: 481 GDIILKRAEGFQMKVEPR 498
            D++LK  E   +++E R
Sbjct: 518 ADVMLKPVEPITIRIERR 535


>UniRef50_UPI0000D56049 Cluster: PREDICTED: similar to Probable
           cytochrome P450 4d14 (CYPIVD14); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Probable cytochrome
           P450 4d14 (CYPIVD14) - Tribolium castaneum
          Length = 487

 Score =  188 bits (458), Expect = 3e-46
 Identities = 104/238 (43%), Positives = 137/238 (57%), Gaps = 9/238 (3%)

Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321
           N+    G+KK  AFLDL+++ S     K+SD +I+EEVDT MF GHDTTA G  F L LL
Sbjct: 253 NETEKSGKKK--AFLDLLLKFSD--IEKLSDRDIREEVDTFMFAGHDTTATGVCFALYLL 308

Query: 322 GIHQDVQARVYDELYQIFGDSDRP-ATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380
             + +VQ +V  E  ++FGD   P  T+ +   MKYLE VI E+LRLYP VPVI R L  
Sbjct: 309 ANNPEVQEKVLSEQKELFGDEKNPCVTYQELQNMKYLEYVIKETLRLYPSVPVIGRYLKE 368

Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440
           D T   +  VI A T V I  + +HR P Y+ +PE F P+ F  EN  N   Y+YIPFSA
Sbjct: 369 DTTFGDR--VISAKTNVAIFIYGIHRNPDYFPEPEKFIPERF--ENMTNLPPYAYIPFSA 424

Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           GPR+C+G+K+A            R+F      P  E  L  + +LK A G ++ +  R
Sbjct: 425 GPRNCIGQKFAMLEMKSLISKVIRHFELTPANPHHELVLAAETVLKSANGIKIGLRAR 482



 Score =  125 bits (301), Expect = 3e-27
 Identities = 64/220 (29%), Positives = 116/220 (52%), Gaps = 2/220 (0%)

Query: 6   HVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLV-DADDIEIILNSHVHIDKATE 64
           H  +   T +++N+   Y + +G ++++ LG      +V D   +E  L+S+  + K+  
Sbjct: 40  HALDAKSTTEILNVTTNYVKKYGKIVKLRLGPFFKALVVTDYKLVEFFLSSNSLLTKSQN 99

Query: 65  YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS-EVG 123
           Y F + WLG GL++++G  W+ HRK++ P FH+ IL+ ++  F+      +EKLKS +  
Sbjct: 100 YAFARSWLGNGLILANGTHWKQHRKILTPAFHLEILREYLETFDSVGRIFIEKLKSLDNV 159

Query: 124 KTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEI 183
           ++ D+   +   T+D++ ETAMG     Q     +Y  +V +MC II  R        + 
Sbjct: 160 QSVDLDALVPLCTLDVICETAMGTKINAQKGENSEYVSSVKEMCRIIVARFLSPLKILKC 219

Query: 184 VFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKG 223
            + +T  F  + K++ I+H  T+KVI  +K    E +  G
Sbjct: 220 TYWMTHDFYTERKVVNILHSFTSKVIDGRKTNRNETEKSG 259


>UniRef50_Q178T9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 511

 Score =  188 bits (457), Expect = 4e-46
 Identities = 132/491 (26%), Positives = 248/491 (50%), Gaps = 38/491 (7%)

Query: 14  QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLG 73
           ++L+ L   Y +    +  + +G K+ + L   + ++ +LN     +K+  Y   +  L 
Sbjct: 54  EELLGLLHSYFRQHDRMFAIHIGPKVAIGLSHPELVQQVLNHPYCQEKSNVYELLR--LP 111

Query: 74  EGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDY 131
            GLL S    W+ HRK +  TF++ IL SF+ IFN ++  +++ L   +  GKTF++   
Sbjct: 112 NGLLSSKYKVWKLHRKTLNSTFNLRILNSFLPIFNDSTRKLIQLLDQYASTGKTFNILAP 171

Query: 132 MSGTTVDILLETAMGISRKTQDESGFDYAMAVMK-MCDIIHQRHYKFWMRSEIVFKLTSF 190
           ++  T+ ++ ET+ G  +K  +  G +     ++ +   + +R     + SEI+++LT  
Sbjct: 172 LTHCTLGMVCETSFG--KKVLEREGKEQFFDDLEVLLTSLGKRVVNVLLHSEIIYRLTPM 229

Query: 191 FKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDT 250
           ++ +TK   +    T+KVI+ K+   +E+   G                L     TLSD 
Sbjct: 230 YRDETKSRAVCRQFTDKVIEEKR-IEIESSFAG-------------DSSLITTEGTLSDD 275

Query: 251 VFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTT 310
             + Y+    F D+        L  + LM +S+ N T    D EI ++V T++  G++T+
Sbjct: 276 EGEAYKRPQIFIDQ--------LLKMPLMTKSAYNFT----DLEISDQVFTMIIAGNETS 323

Query: 311 AAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTL-EMKYLERVILESLRLYP 369
           A   +    LL ++  +Q + Y E+ Q F +++     AD L ++ Y+E V+ ES+RL P
Sbjct: 324 ATQMAHTCLLLAMNPAIQQKAYQEVQQ-FIETENSYIDADILRKLVYIEAVLKESMRLLP 382

Query: 370 PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQ 428
              +I+RK  +D+ +    ++IP  T +++  + LHR+P  +  D E F P+ FL E+++
Sbjct: 383 VGSLISRKNLQDIVLD--GHIIPKNTPLLMKPYSLHRRPDIWGSDAEQFVPERFLGEDSK 440

Query: 429 NRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRA 488
            RH Y++IPFS GPR C+G +YA            +NF   +++  ++ ++   + L  A
Sbjct: 441 RRHPYAFIPFSGGPRGCIGLRYAMMTLKIMLALILKNFEISTQLKYRDLRIHYQLSLNLA 500

Query: 489 EGFQMKVEPRK 499
               + +E R+
Sbjct: 501 GPHAVSLERRR 511


>UniRef50_Q9U1R5 Cluster: Putative uncharacterized protein cyp-42A1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein cyp-42A1 - Caenorhabditis elegans
          Length = 511

 Score =  186 bits (453), Expect = 1e-45
 Identities = 85/230 (36%), Positives = 149/230 (64%), Gaps = 6/230 (2%)

Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329
           ++R+AFLDLM++ +  G  ++    I EEVDT  FEGHDTT+A  ++ L L+G + ++Q+
Sbjct: 280 RRRMAFLDLMLDMNSKG--ELPMEGICEEVDTFTFEGHDTTSAAMNWFLHLMGANPEIQS 337

Query: 330 RVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389
           +V  E+ ++ G++DRP ++ D  ++KYLE    E+LRLYP VP+IAR+   D+ +  + +
Sbjct: 338 KVQKEIDEVLGEADRPVSYEDLGKLKYLEACFKETLRLYPSVPLIARQCVEDIQV--RGH 395

Query: 390 VIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449
            +P+GT VV+   M+H+ P+Y+ DPE+FNP+ F+    + +H Y+YIPFSAG R+C+G +
Sbjct: 396 TLPSGTAVVMVPSMVHKDPRYWDDPEIFNPERFI--TGELKHPYAYIPFSAGSRNCIGMR 453

Query: 450 YAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
           +A            +N +  +++   E ++  ++I++   G ++K E R+
Sbjct: 454 FAMMEEKCILAIILKNLKVKAKLRTDEMRVAAELIIRPLYGNELKFEKRE 503



 Score =  128 bits (310), Expect = 3e-28
 Identities = 70/210 (33%), Positives = 111/210 (52%), Gaps = 2/210 (0%)

Query: 6   HVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY 65
           H   E   ++   +A    +    + RVWLG    V L  A ++E IL S   ++K   Y
Sbjct: 50  HFSPEEFFEQSQGIAYMMRKGDERITRVWLGGLPFVLLYGAHEVEAILGSPKMLNKPFLY 109

Query: 66  RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSE--VG 123
            F   W+G+GLLIS   KWR  RK++ PTFH +ILK FV ++N++   ++ K +++   G
Sbjct: 110 GFLSAWIGDGLLISKPDKWRPRRKLLTPTFHYDILKDFVEVYNRHGRTLLSKFEAQAGTG 169

Query: 124 KTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEI 183
           +  DV   ++  T+D++ E A+G S   Q +    Y  AV KM DI+ QR  +    S+ 
Sbjct: 170 EYSDVFHTITLCTLDVICEAALGTSINAQKDPHSPYLDAVFKMKDIVFQRLLRPHYFSDT 229

Query: 184 VFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213
           +F L    K+  + + I+H  T+K I  +K
Sbjct: 230 IFNLIGPGKEHDECVKILHEFTSKAIYARK 259


>UniRef50_Q7YXL0 Cluster: Cytochrome P450 monooxygenase; n=2;
           Tribolium castaneum|Rep: Cytochrome P450 monooxygenase -
           Tribolium castaneum (Red flour beetle)
          Length = 491

 Score =  183 bits (445), Expect = 1e-44
 Identities = 91/230 (39%), Positives = 132/230 (57%), Gaps = 4/230 (1%)

Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329
           +KRLA LDL+++    G N I D  I+EEVDT MFEGHDTT+    + L LL  H++VQ 
Sbjct: 264 RKRLAMLDLLLKYKSEGAN-IDDEGIREEVDTFMFEGHDTTSVSICYTLMLLANHREVQE 322

Query: 330 RVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389
            +  E+  +    + P T+A   E+K+++RVI ESLRLYP VP I+R    ++   T  Y
Sbjct: 323 EILKEMEAVL--DEEPPTYAKLQELKFMDRVIKESLRLYPSVPFISRVSGSEIQTKT-GY 379

Query: 390 VIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449
            IP    V +  + +H  P  + DPE F+PD FLPEN Q RH ++YIPFSAG R+C+G+K
Sbjct: 380 TIPKDCMVNLQIYDMHHNPNVFPDPEKFDPDRFLPENIQKRHPFAYIPFSAGSRNCIGQK 439

Query: 450 YAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
           +A            + F   +    K+     D++L+     ++K  PR+
Sbjct: 440 FAMLEIKTVLCGILKKFILEAVDTRKDMAFVSDLVLRPKGSIKVKFVPRR 489



 Score =  122 bits (295), Expect = 2e-26
 Identities = 62/177 (35%), Positives = 102/177 (57%), Gaps = 1/177 (0%)

Query: 41  VFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINIL 100
           V L++ +D+E++L       K+  Y F   WLG GLL S GPKW++ RK++ P FH NIL
Sbjct: 80  VNLLNPEDVELVLTDTKQNTKSFIYHFLHSWLGTGLLTSRGPKWQNRRKILTPAFHFNIL 139

Query: 101 KSFVGIFNQNSNNVVEKLKSEVGKTF-DVHDYMSGTTVDILLETAMGISRKTQDESGFDY 159
           + F+ IFN+ +  +VE L++E  K + DV   ++  T+  + ETAMGI     D     Y
Sbjct: 140 QEFIQIFNEETKRLVEDLEAESHKPYIDVVVPITQFTLLSIGETAMGIKLNASDNDKDGY 199

Query: 160 AMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETY 216
             AV K+  ++  R  + W+ +E ++ LT   +++ K+L  +H  +N VI  +K+ +
Sbjct: 200 KRAVYKIGQLLTYRAPRPWIHNETIYSLTPQGRKEQKVLKSLHSFSNNVIAERKKHF 256


>UniRef50_Q8ISJ7 Cluster: Cytochrome P450 CYP4L4; n=4;
           Noctuidae|Rep: Cytochrome P450 CYP4L4 - Mamestra
           brassicae (Cabbage armyworm)
          Length = 492

 Score =  182 bits (442), Expect = 3e-44
 Identities = 95/239 (39%), Positives = 141/239 (58%), Gaps = 9/239 (3%)

Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321
           ND +D+G K +  FLDL++ +  +G  KI D  ++EEVDT MFEGHDTT +G  + L  L
Sbjct: 262 NDSSDIGTKNKHTFLDLLLLAEIDG-KKIDDESVREEVDTFMFEGHDTTTSGIVYTLHCL 320

Query: 322 GIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380
              +DVQ ++Y+EL  IFG +  R  T+ +  +MKYLE VI ES+RL+PPVP+I R++ +
Sbjct: 321 SKRRDVQEKIYEELKTIFGSEIHRDPTYHELQQMKYLELVIKESMRLFPPVPLIERRIMK 380

Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440
           D  +     V   GT+VV+  F + RQP  + DP  F P+ F       ++ +S++ FSA
Sbjct: 381 DCEVGGLKLV--KGTSVVMNIFQIQRQPDLFDDPLEFRPERF---EAPLKNPFSWLAFSA 435

Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
           GPR+C+G+K+A            +NF  +    E E  L  D++L+   G  +K  PRK
Sbjct: 436 GPRNCIGQKFAMMELKITISEIVKNFFILPAAEEPE--LSADLVLRSKNGVNVKFLPRK 492



 Score =  121 bits (292), Expect = 4e-26
 Identities = 60/202 (29%), Positives = 109/202 (53%), Gaps = 1/202 (0%)

Query: 13  TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72
           + + +NL    ++ +G+  RV   S   V +  +   E +++S  HI K   Y F   WL
Sbjct: 49  SSEFLNLVQRLSEKYGHAFRVHFFSTPYVVICHSKYAEPLVSSTEHITKGRSYSFLTCWL 108

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDY 131
           G+GLL ++G +W+SHRK + P FH NIL++F+ +F +N   + EK++    G+  D+   
Sbjct: 109 GQGLLTATGQRWKSHRKFLTPAFHFNILQNFLPVFCKNQRILTEKIRGMADGRPIDMFPI 168

Query: 132 MSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFF 191
           ++   +D + E+ MG+    Q  S  +Y  ++ ++  I+  R    +   + +F L  + 
Sbjct: 169 IALAALDNVNESIMGVCMDAQKHSQSEYVKSIEELSAIVTMRMQIPFFGEDAIFNLLPYK 228

Query: 192 KQQTKLLGIIHGLTNKVIKNKK 213
            +Q K L ++HG TNKVI  ++
Sbjct: 229 TKQDKALKVLHGQTNKVINARR 250


>UniRef50_UPI00015B61D7 Cluster: PREDICTED: similar to Cytochrome
           P450, partial; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to Cytochrome P450, partial - Nasonia
           vitripennis
          Length = 342

 Score =  181 bits (440), Expect = 5e-44
 Identities = 83/189 (43%), Positives = 126/189 (66%), Gaps = 2/189 (1%)

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
           D +++G++K   FLD +++ S+   N +S  EI+E+VDT MF GHDTT    S+VL  LG
Sbjct: 114 DNDNIGKRKPKVFLDRLMDLSEADENPLSLEEIREQVDTFMFGGHDTTGITISWVLFSLG 173

Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382
              +VQ +V++EL  + G  ++PAT     ++KYL+RVI E+LR+YP  P++ R L+ + 
Sbjct: 174 NAPEVQRKVHEELDNVIGIGNQPATKEQLSQLKYLDRVIKETLRIYPSAPMVGRILDHNT 233

Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442
            I    ++IP G  V +    LHR P+ +  P+ FNPD FLPE++  RH Y+Y+PFSAGP
Sbjct: 234 VID--GHIIPKGVVVNLQILHLHRDPEIWDAPDKFNPDRFLPESSNGRHPYAYVPFSAGP 291

Query: 443 RSCVGRKYA 451
           R+C+G+K+A
Sbjct: 292 RNCIGQKFA 300



 Score = 58.8 bits (136), Expect = 3e-07
 Identities = 28/75 (37%), Positives = 39/75 (52%)

Query: 50  EIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQ 109
           ++IL S     K+  Y FF  WLG GLL SSG  W  +R+++ P FH ++L  F  I  +
Sbjct: 3   QVILKSQTLTRKSNIYEFFAYWLGNGLLTSSGDVWHRNRRLMTPAFHFSMLDQFSEIITE 62

Query: 110 NSNNVVEKLKSEVGK 124
                   +K EV K
Sbjct: 63  KVELFNNCIKMEVDK 77


>UniRef50_UPI0000D56462 Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily v, polypeptide 2; n=2;
           Tribolium castaneum|Rep: PREDICTED: similar to
           cytochrome P450, family 4, subfamily v, polypeptide 2 -
           Tribolium castaneum
          Length = 814

 Score =  180 bits (439), Expect = 6e-44
 Identities = 91/228 (39%), Positives = 136/228 (59%), Gaps = 6/228 (2%)

Query: 267 VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326
           V E+K+  FLD+++    N   ++S  E+++EV T +  G DT A    FVL LLG+HQD
Sbjct: 587 VVEEKKRPFLDVLVGKYLN--EELSYQELEDEVSTFLLAGSDTNATAGCFVLTLLGMHQD 644

Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386
           VQ ++Y+E+ ++ G    P T  D  ++KY ERVI E+LRL+P  P IAR  + D+ +  
Sbjct: 645 VQEKLYEEIIEVLGPEKYP-TLDDLPKLKYTERVIKETLRLFPGAPFIARIASDDIDLG- 702

Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446
            +YVIP G+ + +G   LHR  KY+++P  FNP+ FLPEN   RH Y+++PFS G R+CV
Sbjct: 703 -DYVIPRGSNIAVGYVHLHRSEKYWEEPLKFNPERFLPENVAKRHPYTWLPFSGGLRNCV 761

Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPE-KEFKLQGDIILKRAEGFQM 493
           G K+             R FR  S +    + +L  +I+LK   GF++
Sbjct: 762 GGKFGMMVMKIMISMIIRKFRVKSSVKSVGDIELTANIVLKPKNGFRL 809



 Score = 62.1 bits (144), Expect = 3e-08
 Identities = 33/132 (25%), Positives = 69/132 (52%), Gaps = 2/132 (1%)

Query: 84  WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLE 142
           W+ HR++I PT + +IL +F  I  Q  + ++E L+ +  K   D + +++   VD++ E
Sbjct: 433 WKKHRRIIVPTLNQSILNTFPQIICQQCDILLEILEKKCDKGEIDHYKFVTNFAVDVVSE 492

Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202
           T  G+    Q     +Y+    K+ +++  R ++    S+ +F  T  +K + + + ++ 
Sbjct: 493 TIFGVPLNAQITDA-NYSRTFDKIMEVVFMRIFRVDYHSDFLFSWTKEYKAEQENVKLVK 551

Query: 203 GLTNKVIKNKKE 214
             T  +I+ KKE
Sbjct: 552 ETTRDLIERKKE 563


>UniRef50_Q8ISJ8 Cluster: Cytochrome P450 CYP4S4; n=3;
           Noctuidae|Rep: Cytochrome P450 CYP4S4 - Mamestra
           brassicae (Cabbage armyworm)
          Length = 492

 Score =  180 bits (438), Expect = 8e-44
 Identities = 94/228 (41%), Positives = 138/228 (60%), Gaps = 7/228 (3%)

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
           D+  +G KKR A LDL++E+   G  +I    I+EEV+T+MFEGHDTTA      L L+ 
Sbjct: 263 DDVSIGGKKRYAMLDLLLEAENKG--EIDLEGIREEVNTLMFEGHDTTAMAIVLGLMLIA 320

Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382
            H++VQ R+++E  +I GDSDR  T +D  +MKYLE VI E+LRLYP VP IAR++  D 
Sbjct: 321 DHEEVQDRIFEECQKILGDSDRTPTMSDLADMKYLEAVIKETLRLYPSVPFIAREITEDF 380

Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442
            +   +  +  G+ V I  + LHR+P  + +P+ F PD FL  +    H Y+++PFSAGP
Sbjct: 381 MLD--DLPVKKGSEVSIHIYDLHRRPDLFPEPDAFIPDRFL--SGAPMHPYAFVPFSAGP 436

Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEG 490
           R+C+G+++A            RNFR   ++      L  D+++ R EG
Sbjct: 437 RNCIGQRFAMLEMKCVFSAICRNFRLAPKVQGYRPALLADMLI-RPEG 483



 Score =  116 bits (280), Expect = 1e-24
 Identities = 59/195 (30%), Positives = 106/195 (54%), Gaps = 1/195 (0%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82
           Y + +G+   + +  + I+ L +  D+E++L+   +I K+  Y F + WLG GLL+SSG 
Sbjct: 59  YKKEYGDRYVIKMMKRRILHLSNEKDVEVVLSHSRNIKKSKPYTFLEAWLGTGLLLSSGA 118

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLE 142
           KW   RK++ PTFH NILKSF  +  + S ++VE L +  G   ++   +S  T+  + E
Sbjct: 119 KWHRRRKILTPTFHFNILKSFTVVMKEKSRSLVETLNNLEGTEVNLLPVISDYTLYTICE 178

Query: 143 TAMGISRKTQDES-GFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGII 201
           TAMG        S   +Y  A++++ +++  R  + W+ +E +FK     ++    L  +
Sbjct: 179 TAMGTQLDADKSSKTLEYKTAILEIGNLLLGRLTRVWLHNEYLFKKFPIGRRFENCLEKV 238

Query: 202 HGLTNKVIKNKKETY 216
           H   + VI  +K+ +
Sbjct: 239 HSFADDVIMERKKNW 253


>UniRef50_O17851 Cluster: Putative uncharacterized protein cyp-37B1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein cyp-37B1 - Caenorhabditis elegans
          Length = 509

 Score =  178 bits (433), Expect = 3e-43
 Identities = 90/230 (39%), Positives = 135/230 (58%), Gaps = 4/230 (1%)

Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328
           +K+ +AFLDL++E    G   +++ +I+EEVDT MFEGHDTT+A   + L  L  + + Q
Sbjct: 280 DKRSMAFLDLLLELRNEGL--MNEDDIREEVDTFMFEGHDTTSASMGWTLWCLAHNPEFQ 337

Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
            +V  E+  IFG SDR  T  D  +MKYLE+ + ESLR+YP VP   R + +DV I+   
Sbjct: 338 EKVIQEVDGIFGTSDRDCTNDDLKQMKYLEKCLKESLRMYPSVPFFGRTVEQDVVINGDF 397

Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
           +  P G  +++   +L R P  + +P  +NP+NF  +   +RH YS IPFSAGPR+C+G+
Sbjct: 398 F--PKGVRIIVMPLLLQRNPLIFDNPNQYNPENFSEDKIGSRHAYSDIPFSAGPRNCIGQ 455

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           K+A            R +R  +  P    K+  ++ILK + GF + V  R
Sbjct: 456 KFAMMEEKAVISWFFRKYRVTASQPFGMNKILPELILKSSLGFPLTVHHR 505



 Score =  117 bits (281), Expect = 8e-25
 Identities = 62/206 (30%), Positives = 107/206 (51%), Gaps = 2/206 (0%)

Query: 13  TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72
           T + + LA  Y Q     I +WLG   ++ +++    + IL S+  I KA EY    PWL
Sbjct: 63  TTQSMELAQYYCQKGCGTIGLWLGPVPLIAVINPQHAKEILESNEVITKAEEYDILFPWL 122

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHD 130
           G GLL S+G KWR  RKM+ P FH  +L  F+ + +  +   +E++K  ++ GK  D+  
Sbjct: 123 GTGLLTSTGSKWRQRRKMLTPAFHFKVLNDFLSVHDYQAKVFLEQIKPYADSGKEVDLFP 182

Query: 131 YMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSF 190
           Y+    +D++ +T+MG++   Q+     Y  +V  + +   +   + W+R + ++ LT  
Sbjct: 183 YIKRLALDVICDTSMGVTIDAQNNHDHQYVESVRLLSEYAFEWILRPWLRLKPLWYLTGP 242

Query: 191 FKQQTKLLGIIHGLTNKVIKNKKETY 216
             +  + L I+   T  VIK K E +
Sbjct: 243 GHEYDRHLKIVTDFTKTVIKEKWEEF 268


>UniRef50_A1BPS5 Cluster: CYP4BJ1; n=1; Ips paraconfusus|Rep:
           CYP4BJ1 - Ips paraconfusus
          Length = 464

 Score =  178 bits (433), Expect = 3e-43
 Identities = 82/182 (45%), Positives = 123/182 (67%), Gaps = 4/182 (2%)

Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328
           EKKRLAFLDL+++  Q  T +++D +I+EEVDT MFEGHDT ++   F +  +     +Q
Sbjct: 285 EKKRLAFLDLLLDL-QYETGRLNDEDIREEVDTFMFEGHDTVSSSMGFFVFSMSQRLHLQ 343

Query: 329 ARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387
            +VY+E+ +IFG D +R  T  D  +MKYLE+ I E +RL P VP+I R ++ D  I   
Sbjct: 344 EKVYEEMLEIFGNDEERDVTSEDISQMKYLEQCIREVMRLLPTVPIIGRIISEDTNIG-- 401

Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447
            Y++P  TT +I  F + R  ++Y +P+ F+PD+F PE  + R+ ++YIPFSAGPR+C+G
Sbjct: 402 GYMVPKNTTAMIAPFAVQRDKRFYHNPDAFDPDHFTPERVKQRNPFAYIPFSAGPRNCIG 461

Query: 448 RK 449
           +K
Sbjct: 462 QK 463



 Score =  107 bits (257), Expect = 7e-22
 Identities = 47/121 (38%), Positives = 74/121 (61%), Gaps = 2/121 (1%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           ++RVW+G K +VF+   +  ++IL S   I K  EY   + WLG GLL S+G KW + RK
Sbjct: 81  IMRVWIGPKPLVFIYKPETAKVILESQTLITKPGEYGILERWLGTGLLTSTGEKWHTRRK 140

Query: 90  MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLETAMGI 147
           M+ PTFH +IL +F+ +FN+ +N ++E L      G  FD +  +    +D++ E AMG+
Sbjct: 141 MLTPTFHFSILNNFMKVFNRQANTLIENLDRHAADGYPFDFYKVIKALALDVICEAAMGM 200

Query: 148 S 148
           +
Sbjct: 201 N 201


>UniRef50_Q9N4Q5 Cluster: Cytochrome p450 family protein 32B1; n=2;
           Caenorhabditis|Rep: Cytochrome p450 family protein 32B1
           - Caenorhabditis elegans
          Length = 516

 Score =  176 bits (428), Expect = 1e-42
 Identities = 93/241 (38%), Positives = 145/241 (60%), Gaps = 4/241 (1%)

Query: 265 NDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324
           ++  E K+LAFLD +++S +   + ++D  I+EEVDT MFEGHDTT++G +F +  LG  
Sbjct: 276 SEQNETKKLAFLDYLLKSQEEHPDILTDEGIREEVDTFMFEGHDTTSSGITFAVWFLGQF 335

Query: 325 QDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383
            + Q RV+DEL +IFG D +R     D  +M YLE+ I E+LR+ PPVP ++RKL  DV 
Sbjct: 336 PEYQQRVHDELDEIFGEDFERIPNSEDIQKMVYLEQCIKETLRMTPPVPFVSRKLTEDVK 395

Query: 384 I--STK-NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440
           I  +TK + ++PAG   +I    + +  +Y++ P  F P++F PE    R  ++++PFSA
Sbjct: 396 IPHATKPDLLLPAGINCMINIITIMKDARYFERPYEFFPEHFSPERVAAREPFAFVPFSA 455

Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500
           GPR+C+G+K+A            RNF   S     E     ++ILK   G Q+ +  R++
Sbjct: 456 GPRNCIGQKFALLEEKVLLSWIFRNFTVTSMTKFPEEMPIPELILKPQFGTQVLLRNRRK 515

Query: 501 V 501
           +
Sbjct: 516 L 516



 Score =  115 bits (276), Expect = 3e-24
 Identities = 61/189 (32%), Positives = 109/189 (57%), Gaps = 6/189 (3%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           V+++WLG    V +   +  +I+L+S V+I K+++Y   K W+G+GLLIS+G KWRS RK
Sbjct: 83  VLKLWLGPIPAVNIARGEIAKIVLDSSVNISKSSQYNKLKEWIGDGLLISTGDKWRSRRK 142

Query: 90  MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGI 147
           M+  TFH  +LK +  IF      +VE L+       +FD+  Y+    +DI+ ETAMG 
Sbjct: 143 MLTQTFHFAVLKEYQKIFGAQGKILVEVLQLRANNKFSFDIMPYIKRCALDIICETAMGC 202

Query: 148 SRKTQDESGFDYAMAVMKMCDII--HQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205
           S  +Q  +  +Y  +V ++ +I+  +++  +FW++   ++ L     +  + + +    T
Sbjct: 203 SISSQRGANDEYVNSVRRLSEIVWNYEKAPQFWLKP--IWYLFGDGFEFNRHVKLTTDFT 260

Query: 206 NKVIKNKKE 214
             VI+N+K+
Sbjct: 261 RDVIENRKK 269


>UniRef50_Q9VXY0 Cluster: Probable cytochrome P450 4s3; n=5;
           Acalyptratae|Rep: Probable cytochrome P450 4s3 -
           Drosophila melanogaster (Fruit fly)
          Length = 495

 Score =  175 bits (426), Expect = 2e-42
 Identities = 88/236 (37%), Positives = 142/236 (60%), Gaps = 12/236 (5%)

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
           +++DVG K+RLAFLD+++ +   G  ++SD +I+EEVDT MFEGHDTT++  +F L LL 
Sbjct: 265 EQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLS 324

Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382
            + DVQ R ++E  ++ G         +   M YLE VI E+LR+YP VP  +RK+  D+
Sbjct: 325 KNPDVQQRAFEEASELEG--------REKESMPYLEAVIKETLRIYPSVPFFSRKVLEDL 376

Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442
            +      +P G ++    +MLHR PK + DPE F+PD FL  N +  H +++  FSAGP
Sbjct: 377 EVG--KLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFL-VNEKQMHPFAFAAFSAGP 433

Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           R+C+G+K+A            R++R + +  + + K   +++ K   G ++++ PR
Sbjct: 434 RNCIGQKFAMLELKTSLAMLLRSYRFLPD-KDHQPKPLAELVTKSGNGIRLRILPR 488



 Score =  151 bits (366), Expect = 4e-35
 Identities = 66/207 (31%), Positives = 119/207 (57%), Gaps = 1/207 (0%)

Query: 15  KLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGE 74
           +++N      +  G V R+W G  L+V   D +DI+ +L ++  + K+  Y   +PWLG+
Sbjct: 51  EILNWLKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGK 110

Query: 75  GLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMS 133
           GLL + G  W   RK++ P FH  IL  F     +N   +V +L+++  G++FD++ Y++
Sbjct: 111 GLLTNGGESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKANGESFDIYPYIT 170

Query: 134 GTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQ 193
              +D + ETAMGI +  Q +S  +Y  AV  +C ++H++ + FW R  + FK T   K+
Sbjct: 171 LFALDAICETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKE 230

Query: 194 QTKLLGIIHGLTNKVIKNKKETYLENK 220
           +   L ++H  TN+VI+ ++E  ++ +
Sbjct: 231 REAALKVLHDETNRVIRLRREQLIQER 257


>UniRef50_A1BPS4 Cluster: CYP4BH1; n=1; Ips paraconfusus|Rep:
           CYP4BH1 - Ips paraconfusus
          Length = 499

 Score =  174 bits (424), Expect = 4e-42
 Identities = 95/261 (36%), Positives = 145/261 (55%), Gaps = 5/261 (1%)

Query: 238 EILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKE 297
           EIL N   ++ +   K   + L    ++DVG K+++AFLDL++ ++ +G     + EI+ 
Sbjct: 242 EILHNFTNSVINKRRKETTEQLKNVKQDDVGRKRKMAFLDLLLSTNIDGRPPTQE-EIRC 300

Query: 298 EVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKY 356
           EVDT MF GHDTT++  S    +L     +Q  V DEL  +FG D     T     E+KY
Sbjct: 301 EVDTFMFAGHDTTSSAMSSAFYVLAKKTQIQKMVRDELQGVFGKDGSTQITHKSLQELKY 360

Query: 357 LERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEV 416
           LE  I E LRLYPP  VI+R    DV    KN+ IP  T + +  +  +R P Y+++ E 
Sbjct: 361 LELFIKEVLRLYPPATVISRVTEEDVQY--KNHTIPKNTLIEMLIYSANRDPDYHENAEE 418

Query: 417 FNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKE 476
           F P+ FL  + + R + +YIPFSAGPR+C+G+K+A             NF  +  IPE+E
Sbjct: 419 FKPERFLDTSGKKRPF-AYIPFSAGPRNCIGQKFAMLEMKTIISKVLMNFEVLPSIPERE 477

Query: 477 FKLQGDIILKRAEGFQMKVEP 497
             +  +++LK   G  ++++P
Sbjct: 478 MVMTTEVVLKAKNGVHVQLKP 498



 Score =  150 bits (364), Expect = 7e-35
 Identities = 71/174 (40%), Positives = 111/174 (63%), Gaps = 3/174 (1%)

Query: 45  DADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFV 104
           D D ++++L+S+  + K  +YR   PWLG+GLL S+G +W+SHRKMI P FH +IL+ FV
Sbjct: 86  DHDLLDLVLSSNKILTKGGDYRTTAPWLGQGLLTSNGLQWKSHRKMITPAFHFSILEQFV 145

Query: 105 GIFNQNSNNVVEKLKSE-VGKT-FDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMA 162
            IFN   + +V KL+ + + KT  D++ Y++   +DI+ ETAMG++  +Q+    +Y  A
Sbjct: 146 DIFNSQGDTLVNKLQRDALEKTSIDIYQYVTACALDIICETAMGVNLNSQENHDLEYVQA 205

Query: 163 VMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVI-KNKKET 215
           V  MC II  R +  W   + ++ L+   K+Q ++L I+H  TN VI K +KET
Sbjct: 206 VKDMCRIIMDRTFSLWKSFDCLYNLSKLGKKQEQVLEILHNFTNSVINKRRKET 259


>UniRef50_UPI0000D55B03 Cluster: PREDICTED: similar to Cytochrome
           P450 4g1 (CYPIVG1); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1) -
           Tribolium castaneum
          Length = 492

 Score =  173 bits (422), Expect = 7e-42
 Identities = 89/230 (38%), Positives = 134/230 (58%), Gaps = 7/230 (3%)

Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           FLD ++E +     + +D E+  E  +++  G D TA   S+ L +L + QD+Q +VY+E
Sbjct: 262 FLDYLVELTDR-EGRWTDEELTNETRSVIMAGSDATALTLSYCLVMLAMFQDIQDKVYEE 320

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           L  +FGDSDR  T  D   ++YL+R I E+LR++P   +I R+L  D+TI    + IP G
Sbjct: 321 LCSVFGDSDRFVTVDDLPHLQYLDRFIKETLRVFPVTSMIGRELTTDMTID--GHFIPKG 378

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454
           T++      +HR P+YY DP  F+PD FLPE    RH  ++IPFS GPR+C+G +YA   
Sbjct: 379 TSIGFPILYIHRNPEYYPDPLKFDPDRFLPEEVAKRHPCTFIPFSFGPRNCIGYRYAMMT 438

Query: 455 XXXXXXXXXRNFRTISEIPEK---EFKLQGDIILKRAEGFQMKVEPRKRV 501
                    R+F+ +   P K   E K++ DI  K  EG+ +++E RK V
Sbjct: 439 MKVILATLLRSFKMV-HTPYKEISELKIKFDIATKVDEGYPVRMELRKNV 487



 Score =  104 bits (249), Expect = 6e-21
 Identities = 63/228 (27%), Positives = 113/228 (49%), Gaps = 6/228 (2%)

Query: 13  TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72
           T  ++   +     +  + ++WLG+KL +F  + DDI++ILN    ++K   YR+ K   
Sbjct: 50  THNILENTVRVVSKYRPLCKLWLGNKLTIFPSNPDDIQMILNRS--LEKEEGYRYIKTVF 107

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHD 130
           G GL  S   +W+ HRK+I  T +  +L SF+  +N  +  ++EKLK +   G+  D+  
Sbjct: 108 GHGLFTSPVSEWKGHRKVIVSTLNQQVLNSFMDTYNIYTRELIEKLKIDTKDGQHIDMFP 167

Query: 131 YMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSF 190
            M+  T+DI+  + MG       E    + M + ++ ++   R +  ++  E+ +KL+  
Sbjct: 168 IMTQCTLDIICSSIMGTQMNAMKEES-QFIMWMTRVAELAIIRMFNIYLWPELFWKLSPI 226

Query: 191 FKQQTKLLGIIHGLTNKVIKNKKETYLE-NKAKGIIPPTLEEFTHHSG 237
            K+  +L   I+     VI NK+   L+ +  K I    L E T   G
Sbjct: 227 SKESHELDQKIYNYVKTVIHNKRHKGLKSHTGKKIFLDYLVELTDREG 274


>UniRef50_Q9VMS9 Cluster: Probable cytochrome P450 4ac1; n=5;
           Sophophora|Rep: Probable cytochrome P450 4ac1 -
           Drosophila melanogaster (Fruit fly)
          Length = 509

 Score =  169 bits (412), Expect = 1e-40
 Identities = 84/234 (35%), Positives = 138/234 (58%), Gaps = 5/234 (2%)

Query: 265 NDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324
           ++ G K+R A LD ++ +  +G  +I    I +EV+T MFEG+DTT+    F L +L +H
Sbjct: 279 DEFGRKQRYAMLDTLLAAEADG--QIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALH 336

Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384
           +DVQ + Y+E+  +  DSD  + F    ++ YLE VI ESLR++P VP I R+   +  +
Sbjct: 337 EDVQKKCYEEVENLPEDSDDISMFQFN-KLVYLECVIKESLRMFPSVPFIGRQCVEETVV 395

Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRS 444
           +    V+P  T + I  + + R P+++  P++F PD FLPENT NRH ++Y+PFSAG R+
Sbjct: 396 N--GMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPENTVNRHPFAYVPFSAGQRN 453

Query: 445 CVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           C+G+K+A            RNF+ +     ++   +  I+L+  E  ++K+  R
Sbjct: 454 CIGQKFAILEMKVLLAAVIRNFKLLPATQLEDLTFENGIVLRTQENIKVKLSKR 507



 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 48/178 (26%), Positives = 95/178 (53%), Gaps = 1/178 (0%)

Query: 43  LVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKS 102
           +V  ++ E +  S   I K   Y   +P+LG+GLLIS+  KW S RK + P FH N+L+S
Sbjct: 98  VVRPEEAEEVFQSTKLITKNVVYELIRPFLGDGLLISTDHKWHSRRKALTPAFHFNVLQS 157

Query: 103 FVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMA 162
           F+GIF +     +  L+  +    +++  +   T++ + ETA+G+      E G +Y  A
Sbjct: 158 FLGIFKEECKKFLNVLEKNLDAELELNQVIPPFTLNNICETALGVKLDDMSE-GNEYRKA 216

Query: 163 VMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENK 220
           +  + +++ QR     M     F +   +++  + L I+H  ++++I+ K++ + + +
Sbjct: 217 IHAIEEVLIQRVCNPLMYYNWYFFVYGDYRKHLQNLRIVHDFSSRIIERKRQQFQQKQ 274


>UniRef50_Q16IS6 Cluster: Cytochrome P450; n=12; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 510

 Score =  167 bits (405), Expect = 8e-40
 Identities = 89/244 (36%), Positives = 134/244 (54%), Gaps = 7/244 (2%)

Query: 259 LDFNDEND-VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFV 317
           ++  +EN  +  KKR A LD ++ + Q     I +  I+EEVDT  FEGHDTTAA   F+
Sbjct: 270 VELTEENIYLNPKKRYAMLDSLLLAEQK--QLIDEAGIREEVDTFAFEGHDTTAAALVFI 327

Query: 318 LCLLGIHQDVQARVYDELYQIFGD---SDRPATFADTLEMKYLERVILESLRLYPPVPVI 374
              L     VQ R+Y E+ Q++ +   S R  T  D  EMK+L+R + E LRL+PPV  I
Sbjct: 328 FFTLAREPAVQDRIYREILQVYSNKPQSSRAFTPQDYSEMKFLDRALKECLRLWPPVTFI 387

Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434
           +R ++ D+ +   + +IPAG    I    +H  P+ + DPE F+ D FLPE    R+ Y+
Sbjct: 388 SRSISEDIILDDGS-LIPAGCVANIHIMDMHHDPEQFPDPERFDADRFLPEQVDRRNPYA 446

Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMK 494
           Y+PFSAGPR+C+G+KYA              FR +     ++     D++L+     +++
Sbjct: 447 YVPFSAGPRNCIGQKYAMMELKVVVVNALLKFRVLPVTKLEDINFVADLVLRSTNPIEVR 506

Query: 495 VEPR 498
            E R
Sbjct: 507 FERR 510



 Score =  100 bits (239), Expect = 1e-19
 Identities = 61/201 (30%), Positives = 106/201 (52%), Gaps = 6/201 (2%)

Query: 23  YAQTFGNVIRVWLGSKLIVF-LVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSG 81
           + + +G   R W  S L V  +V   + E IL+S  +IDK+  Y+F  P+LG GLL S+G
Sbjct: 67  WPKRYGGSYRFWFSSTLYVLNVVRVREAEHILSSTRNIDKSRFYKFLHPFLGLGLLNSNG 126

Query: 82  PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFD--VHDYMSGTTVDI 139
            KW   R+++ P+FH NIL  F   F +  + ++  +   V K     +   MS  T++ 
Sbjct: 127 SKWMHRRRILTPSFHFNILNGFHHTFVEECDQLLATIDEHVDKGVPTALQPVMSKFTLNT 186

Query: 140 LLETAMGISRKTQDESGFD-YAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLL 198
           + ET+MG+  K    SG D Y   + ++ +++  R  + W+ ++ + +LT +     KLL
Sbjct: 187 ICETSMGV--KLSTVSGADVYRTKLYEIGEVLVHRLMRPWLLNDFLCRLTGYKAAFDKLL 244

Query: 199 GIIHGLTNKVIKNKKETYLEN 219
             +H  T  +I  K++ + E+
Sbjct: 245 LPVHLFTTGIINMKRKQFQES 265


>UniRef50_UPI00015B5E04 Cluster: PREDICTED: similar to CG8302-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG8302-PA - Nasonia vitripennis
          Length = 508

 Score =  166 bits (404), Expect = 1e-39
 Identities = 84/230 (36%), Positives = 129/230 (56%), Gaps = 4/230 (1%)

Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330
           K+ + L+ M+E+S+      SD +I  E  T M  G D+    ++  L LL  H D Q +
Sbjct: 277 KKTSLLEYMMETSERNPEWFSDEDIINECCTFMLAGQDSVGTATAMTLFLLANHPDWQDK 336

Query: 331 VYDELYQIF--GDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
             +EL +IF  G+++RP T  D   M++LE  I E+LRLYP VP+ ARKL  DV +    
Sbjct: 337 CREELDEIFAEGETNRPPTMQDLRAMRWLECCIKEALRLYPSVPIFARKLGEDVKVG--K 394

Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
           +VIP+G  V+I  +  HR P ++ DP  F P+ F PEN++ RH Y+Y+PFSAGPR+C+G 
Sbjct: 395 HVIPSGCGVIILPYSTHRLPHHFPDPHSFRPERFSPENSEKRHPYAYLPFSAGPRNCIGN 454

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           K+A            R +R      + E + +  + ++ + G  +K+  R
Sbjct: 455 KFAILEMKAVISAILRRYRLGGVEGKTEVRPKFRLTVRASGGLWLKISQR 504



 Score =  101 bits (241), Expect = 6e-20
 Identities = 54/190 (28%), Positives = 103/190 (54%), Gaps = 3/190 (1%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86
           +G V R W+     V L++ DDI+ +L S  H  K   YR    +LG+GL+ S    WR+
Sbjct: 77  YGPVARFWVTLIPYVILLEPDDIQAVLGSAKHTSKIFVYRLLDNFLGKGLITSDVDTWRT 136

Query: 87  HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMG 146
           HR+++ P FH+++L+ FVG F + ++ + ++L     +  D+  +++    +IL ET +G
Sbjct: 137 HRRLLQPAFHLHVLQKFVGSFAERADRLADRLARYDNQQLDITKFVNDAVYEILNETVLG 196

Query: 147 IS-RKTQDESG-FDY-AMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHG 203
           ++   T +E G  D   +   K   ++  R  + W+  + ++KLTS  +Q+ K    +  
Sbjct: 197 VNVASTANEDGVVDLDDLPFRKGQVLMTHRLIRPWLIFDWIYKLTSTGQQEKKQSQDLSA 256

Query: 204 LTNKVIKNKK 213
             +++I+ K+
Sbjct: 257 ACHRIIQEKR 266


>UniRef50_Q16I47 Cluster: Cytochrome P450; n=7; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 506

 Score =  166 bits (403), Expect = 1e-39
 Identities = 87/241 (36%), Positives = 138/241 (57%), Gaps = 6/241 (2%)

Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319
           D  +EN +  K+++ FLDL++  + NG   +S  +I+EEVDT MFEGHDTT +G SF L 
Sbjct: 269 DLQEEN-MYTKRKMTFLDLLLNVTVNG-KPLSREDIREEVDTFMFEGHDTTTSGISFTLW 326

Query: 320 LLGIHQDVQARVYDELYQIFGDSDRPA--TFADTLEMKYLERVILESLRLYPPVPVIARK 377
            L  +QDVQ ++++E+ ++ G     A  T     E+ YL+ V+ ESLRL PPVP+I R 
Sbjct: 327 HLAKYQDVQQKLFEEIDRVLGKDKVNAELTNLQIQELDYLDMVVKESLRLIPPVPIIGRT 386

Query: 378 LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIP 437
           L  D+ ++     IPAGT + I  + +HR PK ++  + F P+ F   N   R  Y +IP
Sbjct: 387 LVEDMEMN--GVTIPAGTQISIKIYNIHRNPKIWEKSDEFIPERFSKTNESKRGPYDFIP 444

Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
           FSAG R+C+G++YA             +F+ +      + + + D++++   G  +K+  
Sbjct: 445 FSAGSRNCIGQRYAMMELKVTIIKLIASFKVLPGDSMDKLRFKTDLVIRPDNGIPIKLVE 504

Query: 498 R 498
           R
Sbjct: 505 R 505



 Score =  135 bits (327), Expect = 2e-30
 Identities = 70/196 (35%), Positives = 118/196 (60%), Gaps = 2/196 (1%)

Query: 37  SKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFH 96
           ++L++ L  + ++E +L +   I K+  Y F +PWLG GLLIS+G KW   RK+I PTFH
Sbjct: 78  NELVMDLSSSKNVEKVLLAK-SIKKSFAYDFLEPWLGTGLLISTGEKWFQRRKIITPTFH 136

Query: 97  INILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRKTQDES 155
            ++L+ F+ +FN+ +N +V KLK++ GK  FD++DY++   +D + ET+MG+    QD+ 
Sbjct: 137 FSMLEGFLEVFNKEANILVSKLKAKAGKDEFDIYDYVTLYALDSICETSMGVQINAQDDP 196

Query: 156 GFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKET 215
             +YA+AV +M   I +R +        +F L  F K+Q K++  +H  TN VI  ++  
Sbjct: 197 NNEYAVAVKQMSTFILRRVFSILRTFPSLFFLYPFAKEQKKVILKLHNFTNSVIDARRAM 256

Query: 216 YLENKAKGIIPPTLEE 231
             + K+   +   L+E
Sbjct: 257 LEKEKSNKNVTFDLQE 272


>UniRef50_Q170T3 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 497

 Score =  165 bits (401), Expect = 2e-39
 Identities = 86/224 (38%), Positives = 131/224 (58%), Gaps = 7/224 (3%)

Query: 248 SDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGH 307
           +D V    R+ L  +DE   G KK+ AFLD+++ +S NG   +++ EI+EEVDT MFEGH
Sbjct: 277 TDNVIVSRRNQLMISDE--FGAKKKDAFLDMLLRTSING-KPLTNLEIREEVDTFMFEGH 333

Query: 308 DTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLR 366
           DTT +   F L  L  H ++Q +VYDE+  + G D       +   ++ Y E  I E+LR
Sbjct: 334 DTTTSAVVFTLFNLAKHPEIQQKVYDEIVSVIGKDPKEKIELSHLHDLSYTEMAIKETLR 393

Query: 367 LYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPE- 425
           L+P VP+I R+   ++TI  K   IPAG  +++G + + R  KY+++P  F P+ F  E 
Sbjct: 394 LFPSVPLIGRRCVEEITIEGK--TIPAGANIIVGIYFMGRDTKYFENPSQFIPERFEGEF 451

Query: 426 NTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTI 469
           + +  + Y YIPFSAGPR+C+G+K+A            R++  I
Sbjct: 452 SVEKFNPYKYIPFSAGPRNCIGQKFALNEMKSVISKLLRHYEFI 495



 Score = 97.1 bits (231), Expect = 1e-18
 Identities = 53/166 (31%), Positives = 94/166 (56%), Gaps = 5/166 (3%)

Query: 51  IILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQN 110
           I+ N H+  DK+ EY +   WLG+GLL+S   KW + RK I P FH  IL+ FV +F++N
Sbjct: 122 ILTNKHL-TDKSGEYDYLSNWLGDGLLLSKRHKWHARRKAITPAFHFKILEQFVDVFDRN 180

Query: 111 SNNVVEKLK--SEVGKTFDVHDYMSGTTVDILL-ETAMGISRKTQDESGFDYAMAVMKMC 167
           +  +V+ L+  ++ GKTFD+  Y+    +D++  E   G   K + E+  ++      + 
Sbjct: 181 AAELVDVLEKHADDGKTFDMFPYVLLYALDVICGELGTGCKLKRKHENLDNFRKCNGNIT 240

Query: 168 DIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213
            +  +R +    R+ + F LT  +++  K L ++HG T+ VI +++
Sbjct: 241 HVSIKRMFDIIRRTSL-FYLTPSYQKLRKALKVLHGYTDNVIVSRR 285


>UniRef50_Q17PE3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 513

 Score =  164 bits (398), Expect = 6e-39
 Identities = 125/458 (27%), Positives = 222/458 (48%), Gaps = 43/458 (9%)

Query: 35  LGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPT 94
           LG  + + +   D +  +L+    ++K   Y F +  L  G+  +    W+  RK + PT
Sbjct: 77  LGPIMGIGISHPDLMHKVLSHPDCLEKPFFYNFVQ--LEHGIFSAEYKLWKGQRKALNPT 134

Query: 95  FHINILKSFVGIFNQNSNNVVEKL-KSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQD 153
           F++ IL SF+ IF   S+ +V  L K   G+T D+  + S  T++++  T +G S   + 
Sbjct: 135 FNMKILNSFISIFEDCSSRMVADLFKCANGETVDMFQFTSKCTLEMVCATTLG-SNVLER 193

Query: 154 ESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213
           E   ++   +  + +++ +R     +  + +++LTS+++++ K            I+ K 
Sbjct: 194 EGSDEFLRNMEGLFELVGKRMLSVELFLDSIYRLTSYYRKEMK------------IRKKI 241

Query: 214 ETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRL 273
           E +  N    II     E      +   +NA T  +             DE+D+  +K  
Sbjct: 242 EEFSGN----IIREKRREHMFCLNQQHLHNASTPKE-------------DEDDI--RKPQ 282

Query: 274 AFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYD 333
            F+D ++  S N +   +D EI   V TIM  G+DT+  G +     L I+ ++Q +VYD
Sbjct: 283 IFIDQLLSLS-NSSRPFTDEEILHNVLTIMIAGNDTSGLGVAHACLFLAIYPNIQQKVYD 341

Query: 334 ELYQIF---GDSDRPATFADTL-EMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389
           E+ + F   G +DR +  AD L +++Y E  + E LR  P  P +AR+  +++ +     
Sbjct: 342 EVMKHFPPDGPNDRISLDADFLRQLEYTEMFLKEVLRHCPVAPTVARQNLKELELDGVR- 400

Query: 390 VIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
            IPAG T+    F LHR+   +  D E F+P+NF PE  + RH Y+++PFS+G R+C+G 
Sbjct: 401 -IPAGNTLSFSFFALHRRKDIWGPDAEKFDPENFAPERCEKRHPYAFMPFSSGSRNCIGG 459

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486
           +YA            RNF   + +     + +  + LK
Sbjct: 460 RYAMISMKVMIVYIVRNFSLKTNLRHSHLRYKFGMTLK 497


>UniRef50_Q16P39 Cluster: Cytochrome P450; n=7; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 504

 Score =  164 bits (398), Expect = 6e-39
 Identities = 79/244 (32%), Positives = 140/244 (57%), Gaps = 4/244 (1%)

Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSS 315
           ++D+DF  E + G++    F++ +++  +    + S   +   +D  +F G+DT+A    
Sbjct: 264 KEDIDFKTE-ETGKRIPENFIECLVKYLR-AEGETSKDAVYPHIDMTVFAGNDTSAKTIC 321

Query: 316 FVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIA 375
            +L +L +H +VQ R Y EL ++  + D+  ++ D   + YLE V  E++RL P VP +A
Sbjct: 322 SILLMLAMHPEVQERCYQELMEVCPEKDQHISYKDAANLTYLEMVCKETMRLLPAVPFMA 381

Query: 376 RKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYS 434
           R  + D+ ++ + + IPA  T+++G F +HR P+ +  + + F+PDNFLP+N   RH YS
Sbjct: 382 RITSGDIVLNDQ-HTIPANCTIIMGIFQIHRDPRIWGPNADNFDPDNFLPDNVAKRHPYS 440

Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMK 494
           YIPFSAGPR+C+G +YA            R +R  + +   + ++   ++L  + G QM 
Sbjct: 441 YIPFSAGPRNCIGTRYAYLSSKIMVGSILRKYRLKTSLTMDKLRISCGLLLHISNGCQMA 500

Query: 495 VEPR 498
           +E R
Sbjct: 501 IEHR 504



 Score = 76.2 bits (179), Expect = 2e-12
 Identities = 53/204 (25%), Positives = 100/204 (49%), Gaps = 11/204 (5%)

Query: 13  TQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72
           T K +   L Y   F + + + +G    V + D + ++++L+S   +DK+ +Y F +  +
Sbjct: 55  TPKAIAGTLKYFSKFPSPVCIHMGPLPHVAIFDPEQLQVVLHSQNCLDKSVQYSFLR--V 112

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDY 131
            E L+ + G  W+  RK + P+F   IL +F  IFN     + ++L+   GK   + +  
Sbjct: 113 SETLISAPGHLWKGQRKALNPSFGPAILTTFAEIFNNKCAILTKRLEEYAGKPERNFYRD 172

Query: 132 MSGTTVDILLETAMGISRKTQ----DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKL 187
           +S  T+D +  TA G     Q     E   D   A MK   ++  R +  W   E +++ 
Sbjct: 173 ISKCTLDQIYATAFGCDFNMQTSLDGERSLDLQEAYMK---VMANRFFSVWKYPEFIYRW 229

Query: 188 TSFFKQQTKLLGIIH-GLTNKVIK 210
           T+ +K++ +L  I H  +T K+++
Sbjct: 230 TAGYKKELELRRIYHETITCKLVQ 253


>UniRef50_Q9V7G5 Cluster: Probable cytochrome P450 4aa1; n=5;
           Diptera|Rep: Probable cytochrome P450 4aa1 - Drosophila
           melanogaster (Fruit fly)
          Length = 514

 Score =  164 bits (398), Expect = 6e-39
 Identities = 91/257 (35%), Positives = 138/257 (53%), Gaps = 4/257 (1%)

Query: 242 NNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDT 301
           N  K L+D   K  +      + N+ G  +R   LD MIE S++  +  ++ +I  E  T
Sbjct: 255 NQKKRLNDFTRKMIQRRRQIQNNNN-GNSERKCLLDHMIEISESNRD-FTEEDIVNEACT 312

Query: 302 IMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVI 361
            M  G D+  A  +F L LL  + + Q R   EL  IF DS+R  T  D  EM+Y+E  I
Sbjct: 313 FMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCI 372

Query: 362 LESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDN 421
            E+LRLYP VP+IARKL  +V ++   + +PAG+ V I  +  HR    Y DPE F P+ 
Sbjct: 373 KEALRLYPSVPLIARKLGEEVRLA--KHTLPAGSNVFICPYATHRLAHIYPDPEKFQPER 430

Query: 422 FLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQG 481
           F PEN++NRH Y+++PFSAGPR C+G ++A            R+++ +    +       
Sbjct: 431 FSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATF 490

Query: 482 DIILKRAEGFQMKVEPR 498
            I L+ + G  ++++ R
Sbjct: 491 RITLRASGGLWVRLKER 507



 Score = 98.7 bits (235), Expect = 3e-19
 Identities = 51/195 (26%), Positives = 103/195 (52%), Gaps = 2/195 (1%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86
           +G+++R+W+       +++ +D+++IL+S  H +K   YR    +LG+GL+ SSG KW +
Sbjct: 84  YGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLGDGLITSSGSKWSN 143

Query: 87  HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSE-VGKTFDVHDYMSGTTVDILLETAM 145
           HR++I P FH N+L+ F+  F   S ++ E L +E VG   ++  Y++   +DIL E  +
Sbjct: 144 HRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIAKYVNNCVLDILNEAVL 203

Query: 146 GISRKTQDESGFDYAMAVMKMCDI-IHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGL 204
           G+  K + +       +  +   I +  R  + W+  + ++  T     +      ++  
Sbjct: 204 GVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMANDELNQKKRLNDF 263

Query: 205 TNKVIKNKKETYLEN 219
           T K+I+ +++    N
Sbjct: 264 TRKMIQRRRQIQNNN 278


>UniRef50_Q9XVA6 Cluster: Putative uncharacterized protein cyp-37A1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein cyp-37A1 - Caenorhabditis elegans
          Length = 508

 Score =  163 bits (396), Expect = 1e-38
 Identities = 85/232 (36%), Positives = 133/232 (57%), Gaps = 4/232 (1%)

Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328
           E K+ AFLD++IE  + G   +   +I+EEVDT MFEGHDTT+AG  + L  L    + Q
Sbjct: 281 ESKKKAFLDMLIEKKEEGG--LGYEDIREEVDTFMFEGHDTTSAGIGWSLWCLANCPEYQ 338

Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
            + ++EL +IF  + R  +  D  +MKYLE+ + E+LR+ P VP +AR +  +V I  K 
Sbjct: 339 KKCHEELDEIFEGTSRECSVEDLKKMKYLEKCVKEALRMRPSVPQMARSVEEEVEIDGK- 397

Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
            ++P G +V+I    +   P+ + + EVF+P+ F  +    RH Y+YIPFSAGPR+C+G+
Sbjct: 398 -ILPKGCSVMISPAFIQNNPRTFPNHEVFDPERFNEDEISKRHAYAYIPFSAGPRNCIGQ 456

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500
           K+A            R F   ++I   E     + I + + GF +K   R++
Sbjct: 457 KFAMQEEKTVISWVLRRFHIHTDIGLLENMPLPETITRPSLGFPLKFTVRQQ 508



 Score =  118 bits (285), Expect = 3e-25
 Identities = 65/215 (30%), Positives = 110/215 (51%), Gaps = 4/215 (1%)

Query: 15  KLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGE 74
           +L N  L Y+    ++   W+G   +V ++  +  + +L S+  I+K++EY  F PWLG 
Sbjct: 64  QLYNWGLEYSTKGSSLAAFWMGPYPMVIVLTPEANKKVLESNALINKSSEYDIFLPWLGT 123

Query: 75  GLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK----TFDVHD 130
           GLL++SG KWR  RKM+ P+FH N+L  F  +FN  S  ++E++++   K    T D   
Sbjct: 124 GLLLASGEKWRGRRKMMTPSFHFNVLIDFQVVFNSQSMILLEQIENAAKKTDDSTIDAFP 183

Query: 131 YMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSF 190
           Y+    +DI+ ETAMG +   Q      Y +AV +M  +  +     W+  + + +L  +
Sbjct: 184 YIKRCALDIICETAMGTTVSAQTNHTHPYVVAVNEMNSLAFKYQRMPWLWIKPIRQLIGY 243

Query: 191 FKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGII 225
                + L I+   T KVI  K   + E     ++
Sbjct: 244 EADFQRNLDIVTSFTKKVIDRKLREHDETDGMVVV 278


>UniRef50_Q9V558 Cluster: Cytochrome P450 4p1; n=5; Sophophora|Rep:
           Cytochrome P450 4p1 - Drosophila melanogaster (Fruit
           fly)
          Length = 513

 Score =  163 bits (396), Expect = 1e-38
 Identities = 89/264 (33%), Positives = 140/264 (53%), Gaps = 9/264 (3%)

Query: 236 SGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDH-E 294
           S EI+A     L D + K         D++    KKR A LD +I + ++G   + DH  
Sbjct: 257 SSEIIAKRRDLLKDELDKSSSTA----DDDGFVSKKRFAMLDTLIYAEKDG---LIDHIG 309

Query: 295 IKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEM 354
           I EEVDT+MFEG+DTT+ G  F L  + ++ D Q   Y E+ +   D           ++
Sbjct: 310 ICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHIDDDLSNLDVGQLNKL 369

Query: 355 KYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDP 414
           KYLE  + E+ RL+P VP++ R+  ++  ++    ++P G  + I  F +HR  KY+  P
Sbjct: 370 KYLEYFMKETTRLFPSVPIMGREAVQETELAN-GLILPKGAQITIHVFDIHRNAKYWDSP 428

Query: 415 EVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPE 474
           E F P+ FLPEN Q+RH Y+Y+PFSAG R+C+G+KYA            + F+ +  I  
Sbjct: 429 EEFRPERFLPENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKVLKAIDP 488

Query: 475 KEFKLQGDIILKRAEGFQMKVEPR 498
           ++      I L+  +  ++K+  R
Sbjct: 489 QKIVFHTGITLRTQDKIRVKLVRR 512



 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 55/191 (28%), Positives = 94/191 (49%), Gaps = 1/191 (0%)

Query: 24  AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK 83
           A+  G     ++  K I  ++DAD  E +LN    I K   Y F  P+L  GLL S+G K
Sbjct: 77  AKEMGTSYIEYVFGKAIYNIIDADSAENVLNHPNLITKGLVYNFLHPFLRTGLLTSTGKK 136

Query: 84  WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLET 143
           W + RKM+ PTFH NIL  F  IF   S   + + + +   T  +HD +   T++ + ET
Sbjct: 137 WHARRKMLTPTFHFNILNQFQEIFKTESQKFLLQFEGQDEVTITLHDVIPRFTLNSICET 196

Query: 144 AMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHG 203
           AMG+      E G  Y     ++ +   +R     +  + +F++ +  K     L ++H 
Sbjct: 197 AMGVKLDEMAEKGDRYRENFSQIEECFIRRLSNPLLWGDKLFEMFA-AKDFASALDVVHR 255

Query: 204 LTNKVIKNKKE 214
            ++++I  +++
Sbjct: 256 FSSEIIAKRRD 266


>UniRef50_Q9N525 Cluster: Cytochrome p450 family protein 29A3; n=6;
           Caenorhabditis|Rep: Cytochrome p450 family protein 29A3
           - Caenorhabditis elegans
          Length = 503

 Score =  163 bits (395), Expect = 1e-38
 Identities = 80/227 (35%), Positives = 126/227 (55%), Gaps = 5/227 (2%)

Query: 242 NNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDT 301
           N  KT +  V    R   +  +      K+ + FLD+++ + ++    +S  ++++EVDT
Sbjct: 249 NIMKTFTRNVIAERRTARESGEVEKETSKRNMNFLDILLSNEESSV--LSPEDLRQEVDT 306

Query: 302 IMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERV 360
            MF GHDTT    S+V   L  H D+Q  VY+E+  +FG D +   T     +++Y ER+
Sbjct: 307 FMFAGHDTTTTSVSWVCWNLAHHPDIQQNVYEEIVSVFGEDPNEDVTTEGIKKLEYTERM 366

Query: 361 ILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPD 420
           + ES R+ P VP + R+L  D+ I     +IPAG  V I    +H+    Y++P++F+PD
Sbjct: 367 LKESKRICPTVPAVLRQLISDMEIG--GVLIPAGANVAIAPMAIHKNANIYQNPDIFDPD 424

Query: 421 NFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467
            FLPE T  RH Y +IPFSAG R+C+G+K+A            +NF+
Sbjct: 425 RFLPEETAKRHAYDFIPFSAGLRNCIGQKFAQLNEKVMVIHLLKNFK 471



 Score = 91.1 bits (216), Expect = 6e-17
 Identities = 52/157 (33%), Positives = 80/157 (50%), Gaps = 3/157 (1%)

Query: 10  ENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFK 69
           E + Q L +L     +   ++IR  +     V+ +D   +  IL S   +DK   Y FF 
Sbjct: 57  EEIFQALRDLFSEAVEKGQSLIRHRILGTFYVWPLDGKTVSKILESTTELDKGGPYEFFN 116

Query: 70  PWLGEGLLISS-GPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTF 126
            WLG G L+   G +WRSHRKM+ PTFH   L+ +  +FN  S  VV+ L   ++ G+T 
Sbjct: 117 DWLGGGTLLEGYGERWRSHRKMLTPTFHFAKLEGYFEVFNTESRVVVDCLDKFAKSGETV 176

Query: 127 DVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAV 163
           D+  +    T+D + +TAMG     Q ++   Y  A+
Sbjct: 177 DLFPFFKRCTLDTICKTAMGAKVDAQLQNSHPYITAI 213


>UniRef50_Q16E69 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 348

 Score =  162 bits (393), Expect = 2e-38
 Identities = 80/192 (41%), Positives = 119/192 (61%), Gaps = 8/192 (4%)

Query: 260 DFNDEND-VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318
           DF++EN  V   +R A LD ++ S     N+I +  I+EEVDT MFEGHDTTA+  +F+ 
Sbjct: 155 DFSEENIYVNTNQRYALLDTLLASEAK--NQIDEEGIREEVDTFMFEGHDTTASAFTFIF 212

Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPA---TFADTLEMKYLERVILESLRLYPPVPVIA 375
            ++  HQ+ Q ++ +E+  +     +P    +  D  E+K+++RVI E LRLYPPVP I+
Sbjct: 213 LVIANHQEAQRQLVEEIEAMIAGRIKPTEPLSMHDYSELKFMDRVIKECLRLYPPVPFIS 272

Query: 376 RKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSY 435
           R +  D  +  +   IP  +   +  F LHR P  + DPE F+PD FLP N + R+ Y+Y
Sbjct: 273 RAILEDALLGDR--FIPKDSMANLHIFDLHRDPDQFPDPERFDPDRFLPANVEKRNPYAY 330

Query: 436 IPFSAGPRSCVG 447
           +PFSAGPR+C+G
Sbjct: 331 VPFSAGPRNCIG 342



 Score = 41.1 bits (92), Expect = 0.067
 Identities = 35/158 (22%), Positives = 72/158 (45%), Gaps = 12/158 (7%)

Query: 141 LETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGI 200
           +ETAMG+   +   +  +Y   + ++  ++  R    W+  E  ++L  F ++  K+L  
Sbjct: 72  IETAMGVKLDSMSMAD-EYRAKIQEVIKLLLLRVMNPWLVEEFPYRLLGFRRRLMKVLKP 130

Query: 201 IHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGE-------ILANNAKTLSDTVFK 253
           IH  T  +IK +++ +  N  K +   + E    ++ +       +LA+ AK   D   +
Sbjct: 131 IHAFTRSIIKQRRDLFHAN-VKNVDDFSEENIYVNTNQRYALLDTLLASEAKNQIDE--E 187

Query: 254 GYRDDLD-FNDENDVGEKKRLAFLDLMIESSQNGTNKI 290
           G R+++D F  E          F+ L+I + Q    ++
Sbjct: 188 GIREEVDTFMFEGHDTTASAFTFIFLVIANHQEAQRQL 225


>UniRef50_A1BPR9 Cluster: CYP4BD1; n=1; Ips paraconfusus|Rep:
           CYP4BD1 - Ips paraconfusus
          Length = 504

 Score =  160 bits (388), Expect = 9e-38
 Identities = 86/233 (36%), Positives = 132/233 (56%), Gaps = 5/233 (2%)

Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327
           G + RLAFLDL++E+  +GT  ++  E+++EV+T MFEGHDTT++  +F L +L  H  V
Sbjct: 275 GIRTRLAFLDLLLEAKIDGT-PLTKAELRDEVNTFMFEGHDTTSSAITFCLLMLATHPRV 333

Query: 328 QARVYDELYQIFGDSDRPA--TFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIS 385
           Q +V  E  +I     + A  T  +  +MKYLE VI E+LRLYP VP+ +RKL  DV   
Sbjct: 334 QDKVMAEQKEILEGDLKLAHPTSKELSQMKYLENVIKETLRLYPSVPLFSRKLGEDVEF- 392

Query: 386 TKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSC 445
            K  + P G T+V+  +  HR P  + +PE F P+ F        + ++Y PFSAG R+C
Sbjct: 393 -KGNLYPKGITLVLTPYATHRDPDIFPEPEKFLPERFEESEMLKINPFAYTPFSAGSRNC 451

Query: 446 VGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           +G+K+A            R+F+     PE + +L  +  L    G ++ ++ R
Sbjct: 452 IGQKFAMMEIKSTVSKVVRHFKLEPAHPEHQIQLVSETTLNSKNGVKISLQAR 504



 Score =  134 bits (324), Expect = 5e-30
 Identities = 68/177 (38%), Positives = 104/177 (58%), Gaps = 6/177 (3%)

Query: 40  IVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINI 99
           +V   D + IE+I +S  HI K ++Y +FK WLG+GLLIS G KWR HRK+I PTFH +I
Sbjct: 83  VVITADPEFIELIYSSSTHITKGSQYDYFKRWLGQGLLISDGDKWRFHRKIITPTFHFSI 142

Query: 100 LKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHDYMSGTTVDILLETAMGISRKT---QDES 155
           L+ F+ +F+   +N V KL+  VG T  ++ + +S  T+DI+ ETAMG+       +D  
Sbjct: 143 LQQFLTVFDTVGDNFVRKLQQHVGSTSVEISNLISLCTLDIICETAMGVKMNALDMKDSE 202

Query: 156 GFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNK 212
             +Y   +  MC II  R + F     I + LT  + ++ + L +++G  + VI  K
Sbjct: 203 NMEYIKGIRIMCKIIVDRMFSF--LHPIFYPLTLNYYREKRALKMVNGYVDNVISQK 257


>UniRef50_UPI0000D5646A Cluster: PREDICTED: similar to CYtochrome
           P450 family member (cyp-31A3); n=2; Tribolium
           castaneum|Rep: PREDICTED: similar to CYtochrome P450
           family member (cyp-31A3) - Tribolium castaneum
          Length = 349

 Score =  159 bits (387), Expect = 1e-37
 Identities = 88/259 (33%), Positives = 146/259 (56%), Gaps = 8/259 (3%)

Query: 242 NNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDT 301
           N  K   D + K +R   D   +N+  EK+    L+ +++ S+    KI    +++E+ T
Sbjct: 97  NCGKDSFDILPKLFRCTFDTACDNNHREKR---LLNHLLKLSKINA-KIDQTALEDEIQT 152

Query: 302 IMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVI 361
           I+  G +TTA      L +LGI+ ++Q ++  EL  IFG  DR  T  D   M+YLERVI
Sbjct: 153 ILLTGSETTALTVGLTLIILGIYPEIQKKIGKELDVIFGKDDRVPTLEDINRMEYLERVI 212

Query: 362 LESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDN 421
            E+LR   PVP + R  N+D+T+ +    IPAG+ ++I  F +H++P+Y+K+P  F+PD 
Sbjct: 213 KETLRFLTPVPFMLRTNNQDITLDSN--TIPAGSCIMIPIFHIHKKPEYWKNPNEFDPDR 270

Query: 422 FLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEK--EFKL 479
           FLPEN+  R   ++IPFS+GPR+C+G KY             R +  ++   +K  + ++
Sbjct: 271 FLPENSSKRPRCAFIPFSSGPRNCIGFKYGMMSVKVLLAVILRKYTVVATEYKKVEDIEM 330

Query: 480 QGDIILKRAEGFQMKVEPR 498
              ++ K   G ++K+E +
Sbjct: 331 LFYVVNKPISGCKIKLEKK 349



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 4/73 (5%)

Query: 70  PWLGEGLLISSGPK---WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-T 125
           P  G    +  G K   W+S RKMI PTF+ NIL SFV IF +++  +   L+   GK +
Sbjct: 43  PIFGSAHYLMGGHKVDVWKSRRKMINPTFNPNILNSFVEIFGRHAFYLTNALEENCGKDS 102

Query: 126 FDVHDYMSGTTVD 138
           FD+   +   T D
Sbjct: 103 FDILPKLFRCTFD 115


>UniRef50_Q27606 Cluster: Cytochrome P450 4e2; n=11; Diptera|Rep:
           Cytochrome P450 4e2 - Drosophila melanogaster (Fruit
           fly)
          Length = 526

 Score =  157 bits (382), Expect = 5e-37
 Identities = 81/207 (39%), Positives = 121/207 (58%), Gaps = 8/207 (3%)

Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329
           +K++AFLD ++ S+ +G   ++  E+ EEV T MFEGHDTT +G SF + LL  HQD Q 
Sbjct: 273 RKKMAFLDTLLSSTIDG-RPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQR 331

Query: 330 RVYDELYQIFGDSD--RPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387
           +++ E  ++ G+S+  R ATF +  +MKYL+  I E+ R+YP VP I R   +D  I   
Sbjct: 332 KLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVID-- 389

Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447
             ++P GTT+ +G  ML    K +KDP  F P+ F     +    + Y+PFSAGPR+C+G
Sbjct: 390 GDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF---ELEKPGPFEYVPFSAGPRNCIG 446

Query: 448 RKYAXXXXXXXXXXXXRNFRTISEIPE 474
           +K+A            RNF  +  + E
Sbjct: 447 QKFALLEIKTVVSKIIRNFEVLPALDE 473



 Score =  122 bits (294), Expect = 2e-26
 Identities = 69/232 (29%), Positives = 115/232 (49%), Gaps = 5/232 (2%)

Query: 4   NIHVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKAT 63
           N H   +N ++ L  +   + Q   +    W+G+   V +  +  +E IL+S   I K+ 
Sbjct: 44  NAHQMGKNPSEILDTVFSWWHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSD 103

Query: 64  EYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG 123
            Y+   PWLG GLL S+G KW  HRKMI P FH NIL+ F  + N+NS   ++ LK+   
Sbjct: 104 IYQLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAA 163

Query: 124 --KTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRS 181
               FD  +     T+D++ +TAMG+S    +        A   MC  I+ R +    R+
Sbjct: 164 GDNIFDFQEQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRN 223

Query: 182 EIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFT 233
           E++++L   +   ++ L  +   TN++I  + E +   K+  +     +EFT
Sbjct: 224 ELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRIEAH---KSGAVSTNAGDEFT 272


>UniRef50_A1BPS3 Cluster: CYP4BG1; n=1; Ips paraconfusus|Rep:
           CYP4BG1 - Ips paraconfusus
          Length = 498

 Score =  157 bits (380), Expect = 9e-37
 Identities = 89/229 (38%), Positives = 125/229 (54%), Gaps = 8/229 (3%)

Query: 270 KKRLAFLDLMI-ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328
           +K    LDL++ E  Q G+  I    I+EEVDT MFEGHDTT+A   F+L  L  +  +Q
Sbjct: 275 RKIYKMLDLLLHEKLQFGS--IDYEGIREEVDTFMFEGHDTTSAALVFLLHNLASNLAIQ 332

Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
            +V  E+  +    +R  TF     + Y +RVI ESLRLYP VP I+R  + D    T  
Sbjct: 333 EKVRQEIKTV----ERIPTFQTLQNLPYTDRVIKESLRLYPSVPFISRIASEDFITHT-G 387

Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
           Y I  GT + +  F LHR P+ Y DP  F+PD FLPE  + RH ++Y+PFSAGPR+C+G+
Sbjct: 388 YSISKGTVLYMHIFDLHRNPEIYPDPLTFDPDRFLPEKVKERHPFAYLPFSAGPRNCIGQ 447

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
           K+A              FR   +    +   Q D+IL+     ++  +P
Sbjct: 448 KFAMLELKAVLWGLLHKFRLTLDPSTTQINFQVDLILRTQGEIKINFQP 496



 Score =  116 bits (278), Expect = 2e-24
 Identities = 76/288 (26%), Positives = 143/288 (49%), Gaps = 15/288 (5%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82
           +A+ +G + R+ +    IV      D+EIIL+   H+ K+  Y+F + WLG+GLL S+G 
Sbjct: 62  FARDYGPIYRISIPFLDIVNFFHPADLEIILSQKKHMKKSLLYQFLEGWLGKGLLTSTGS 121

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT------FDVHDYMSGTT 136
           KW+  RK++   FH NIL+ FV +FN+ + ++V++++ E+  T        V   ++  T
Sbjct: 122 KWQFRRKLLTQAFHFNILQKFVRVFNEETTHLVKRIE-EINLTGQSQAGISVLPLITHLT 180

Query: 137 VDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTK 196
           +  + ET++G+S   + E+   Y   + KM D +  R  K W     ++  T   KQ+  
Sbjct: 181 LQSVTETSLGVS-NIEKETLKAYRENIYKMGDFLIDRLRKPWRLFNFIYHFTEASKQEQL 239

Query: 197 LLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLE-EFTHHSGEILANNAKTLSDTVFKGY 255
            +  +H  T +VIK ++E    +K + ++  T      +   ++L +         ++G 
Sbjct: 240 TINKLHQFTYQVIKEREEVLQSDKTQSVMTSTYSGRKIYKMLDLLLHEKLQFGSIDYEGI 299

Query: 256 RDDLD-FNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTI 302
           R+++D F  E        L FL   + S     N     ++++E+ T+
Sbjct: 300 REEVDTFMFEGHDTTSAALVFLLHNLAS-----NLAIQEKVRQEIKTV 342


>UniRef50_P33269 Cluster: Cytochrome P450 4d1; n=11; Diptera|Rep:
           Cytochrome P450 4d1 - Drosophila melanogaster (Fruit
           fly)
          Length = 512

 Score =  157 bits (380), Expect = 9e-37
 Identities = 81/241 (33%), Positives = 139/241 (57%), Gaps = 8/241 (3%)

Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321
           ND+ DVG K+++AFLD++++S+ +    +S+ +I+EEVDT MFEGHDTT++   F    +
Sbjct: 274 NDDADVGAKRKMAFLDILLQSTVD-ERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNI 332

Query: 322 GIHQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380
             H + Q + ++E+  + G D   P ++    ++ Y++  + E+LR+YP VP++ RK+  
Sbjct: 333 ATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLE 392

Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNF-LPENTQNRHYYSYIPFS 439
           D  I+ K  +IPAGT + I    L R+ + + +P  F P+ F +    +  + Y+YIPFS
Sbjct: 393 DCEINGK--LIPAGTNIGISPLYLGRREELFSEPNSFKPERFDVVTTAEKLNPYAYIPFS 450

Query: 440 AGPRSCVGRKYAXXXXXXXXXXXXRNFRT--ISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
           AGPR+C+G+K+A            R++    + +  E    L  ++IL+  E    KV  
Sbjct: 451 AGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPV-LIAELILRTKEPLMFKVRE 509

Query: 498 R 498
           R
Sbjct: 510 R 510



 Score =  141 bits (342), Expect = 3e-32
 Identities = 67/206 (32%), Positives = 118/206 (57%), Gaps = 6/206 (2%)

Query: 15  KLVNLALGYAQTFGN--VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWL 72
           ++V     + +T+    V++VWLG +L V + +  D+E++L +    DKA EY+  +PWL
Sbjct: 56  EMVKKIFEFMETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWL 115

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK----TFDV 128
            EGLL+S G KW   RK+I P FH  IL  FV +F + S +++  ++ +  K     F +
Sbjct: 116 KEGLLVSRGRKWHKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGESGFSL 175

Query: 129 HDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLT 188
           +D+++  T+D + ETAMG+S   Q  +  +Y  AV  +  ++H+R +    R ++ + LT
Sbjct: 176 YDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLT 235

Query: 189 SFFKQQTKLLGIIHGLTNKVIKNKKE 214
              + + K L ++H  T K+I  ++E
Sbjct: 236 PLARAEKKALNVLHQFTEKIIVQRRE 261


>UniRef50_O46054 Cluster: Cytochrome P450 4ae1; n=1; Drosophila
           melanogaster|Rep: Cytochrome P450 4ae1 - Drosophila
           melanogaster (Fruit fly)
          Length = 496

 Score =  157 bits (380), Expect = 9e-37
 Identities = 85/226 (37%), Positives = 131/226 (57%), Gaps = 6/226 (2%)

Query: 274 AFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYD 333
           A LD ++ ++ +G   ++D +I++EV+T +FEGHDTT +  SF L LL  H+ VQ ++++
Sbjct: 274 ALLDTLLRATVDG-QPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFE 332

Query: 334 ELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIP 392
           EL   +G D  R    +D   + YL  V+ ESLRLYPP+P +AR L +D+ I  + Y IP
Sbjct: 333 ELRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLEKDLVID-EGY-IP 390

Query: 393 AGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 452
            GT VV+  + L R    + DP VF P+  L E       YSYIPFSAGPR+C+G+K+A 
Sbjct: 391 VGTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFAL 450

Query: 453 XXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
                      R+++ +    + E  ++  I+L+   G  + + PR
Sbjct: 451 LEMKTMVTKVIRHYQLLPMGADVEPSIK--IVLRSKSGVNVGLRPR 494



 Score = 97.1 bits (231), Expect = 1e-18
 Identities = 60/211 (28%), Positives = 110/211 (52%), Gaps = 11/211 (5%)

Query: 8   QEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRF 67
           Q +NL  K       Y + FG      +   +++   +   I+ +L     + K T Y  
Sbjct: 53  QPDNLHDKFAE----YVKRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQHQLKKGTMYFA 108

Query: 68  FKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKT 125
            + WLG+GLL+S G +W + RK+I PTFH +IL+ FV +F++ S+ +VE+L+  S   + 
Sbjct: 109 LRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEV 168

Query: 126 FDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVF 185
            +++  +    +DI+ ETAMG++   Q     +   AV  + +I+  R  +  +    +F
Sbjct: 169 VNIYPLVGLAALDIITETAMGVNVDAQGADS-EVVHAVKDLTNILATRFMRPHLLFPHLF 227

Query: 186 KL---TSFFKQQTKLLGIIHGLTNKVIKNKK 213
           +L   + F KQQ  ++  +H  TN +I+ ++
Sbjct: 228 RLCWPSGFRKQQAGVI-CLHEFTNGIIEQRR 257


>UniRef50_Q9VLZ7 Cluster: Probable cytochrome P450 4d21; n=5;
           Sophophora|Rep: Probable cytochrome P450 4d21 -
           Drosophila melanogaster (Fruit fly)
          Length = 511

 Score =  156 bits (379), Expect = 1e-36
 Identities = 80/240 (33%), Positives = 138/240 (57%), Gaps = 7/240 (2%)

Query: 264 ENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323
           ++D+G K ++  LD++++++ +    +SD +I+EEVD  +F G DTT +G S  L  +  
Sbjct: 276 DDDIGGKAKMTLLDILLQATIDN-KPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISR 334

Query: 324 HQDVQARVYDELYQIFG-DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382
           H  VQ  +Y+EL  + G D D   T    LE+KYL+ VI E++RL+PPVP++ R +  D+
Sbjct: 335 HPKVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDL 394

Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP-ENTQNRHYYSYIPFSAG 441
            I      IP  T++++  + ++R P+Y+ DP VF P+ ++  + T N    +YIPFS+G
Sbjct: 395 KIG--EITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSG 452

Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRV 501
           P++C+G+K+A            R++  +      + K     IL  + G  + ++PR RV
Sbjct: 453 PKNCIGQKFANLQMKALISKVIRHYELLP--LGADLKATYTFILSSSTGNNVGLKPRTRV 510



 Score =  130 bits (313), Expect = 1e-28
 Identities = 80/250 (32%), Positives = 129/250 (51%), Gaps = 5/250 (2%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82
           Y   +G   R+W+  + +++  D    E IL+S   + KA  YRF + +LG+GLL+S+G 
Sbjct: 63  YFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLSTGN 122

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKT-FDVHDYMSGTTVDIL 140
           KW S RK++AP FH   L++FV I ++NS  +VEKLK+   GKT  D+  ++S   +D+ 
Sbjct: 123 KWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVT 182

Query: 141 LETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTS--FFKQQTKLL 198
            ETAMG+    Q+E  F Y  A+  +  I  +R     MR   +F L +   +++  K +
Sbjct: 183 TETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDI 242

Query: 199 GIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAK-TLSDTVFKGYRD 257
            I+   T+KVI+ ++      +A G   P +       G+         L  T+      
Sbjct: 243 AIMQDFTDKVIRERRAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNKPLS 302

Query: 258 DLDFNDENDV 267
           D+D  +E DV
Sbjct: 303 DVDIREEVDV 312


>UniRef50_UPI00015B5723 Cluster: PREDICTED: similar to cytochrome
           P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 523

 Score =  155 bits (377), Expect = 2e-36
 Identities = 83/228 (36%), Positives = 128/228 (56%), Gaps = 5/228 (2%)

Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328
           ++ RL  L+ +I+ +   TN ++D E+++E  TI     DTT   SSF L  L I+Q++Q
Sbjct: 299 DRPRLMLLEQLIDHNAK-TNLMNDTELRDETYTIFTAAQDTTGVISSFALLNLAINQEIQ 357

Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
            +V +E+  + G+     T     E+KY E VI E+LRLYP  P++ R+   D+ + T  
Sbjct: 358 DKVREEIRNVVGNDS--VTVEHLPELKYTELVIKETLRLYPIAPLMVREATGDIDLET-- 413

Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
             +P G ++V+  +  HR  KY+ DPE F P+ FLPEN+  RH Y+YIPFS G R CVG+
Sbjct: 414 CTLPKGCSIVMIPYETHRSTKYWTDPEKFIPERFLPENSVGRHPYAYIPFSGGLRGCVGQ 473

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496
           K+A            R  R  S    +  +L+ DI ++  +G+ + VE
Sbjct: 474 KFAIMCLKTMLVHVIRKVRLTSTQNLETLRLKADISVRSRDGYMVSVE 521



 Score =  117 bits (282), Expect = 6e-25
 Identities = 68/235 (28%), Positives = 112/235 (47%), Gaps = 9/235 (3%)

Query: 32  RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMI 91
           R WLG KL + L +  D E+IL  H    K   Y F +P++G+GL+  SGP  R+HRK I
Sbjct: 103 RFWLGPKLFIILAEPRDYEVILGCHKASYKDKMYEFIEPFVGKGLVSGSGPVHRAHRKAI 162

Query: 92  APTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRK 150
            P  +   L  ++  F+ +S    E L+ + G   FD+  +M   T D++ +T +G+   
Sbjct: 163 MPMLNSKALNEYLKHFDTHSRICSELLEEKAGTGVFDIQPFMVHCTFDMIFDTILGMPGS 222

Query: 151 TQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIK 210
           +Q E   +      KM +++H R  K W+ ++ +F  T   K+Q +   +IH      + 
Sbjct: 223 SQKEGHKELVYWTEKMYELVHTRMIKVWLHADWIFSWTDLGKKQKEGQHVIHSFIETAVA 282

Query: 211 NKKETYLENKAKGIIPP-----TLEEFTHHSGEILANNAKTLSD---TVFKGYRD 257
            KK+ +   +   I P       LE+   H+ +    N   L D   T+F   +D
Sbjct: 283 RKKKEHYAIERDAIAPDRPRLMLLEQLIDHNAKTNLMNDTELRDETYTIFTAAQD 337


>UniRef50_Q16L55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 463

 Score =  155 bits (376), Expect = 3e-36
 Identities = 79/185 (42%), Positives = 116/185 (62%), Gaps = 3/185 (1%)

Query: 264 ENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323
           EN  G+K ++ FLD + E +     ++S  +I E +DTI+F G+DTTA   S +L +L +
Sbjct: 271 ENTDGKKPQI-FLDKLFELAVENKQQLSKEDIPEHLDTIIFAGNDTTATTMSNLLLMLAM 329

Query: 324 HQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383
           H DVQ RVY E+ +   D ++P +  DT ++ Y E V  E++RL+P  P+I R    D+ 
Sbjct: 330 HPDVQERVYQEVMEACPDLEQPVSMEDTAKLTYTEMVCKETMRLFPVGPLIGRIAEVDIK 389

Query: 384 ISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442
           IS + +VIPAG+ V  G +M+HR  K +    E FNPD+FLPEN    H Y+Y+PFS G 
Sbjct: 390 ISDE-HVIPAGSEVGCGIYMVHRDRKIWGPRAEEFNPDHFLPENISKIHPYAYLPFSGGI 448

Query: 443 RSCVG 447
           R+C+G
Sbjct: 449 RNCIG 453



 Score = 79.4 bits (187), Expect = 2e-13
 Identities = 56/227 (24%), Positives = 108/227 (47%), Gaps = 8/227 (3%)

Query: 6   HVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY 65
           +  +E + +  V L   Y+   G    + LG   +V +   + ++ +L+S   I +   Y
Sbjct: 51  YTSQEKIFETFVELGSTYSSPMG----IELGPITLVVVYQPEHLQAVLSSPHCISRPFWY 106

Query: 66  RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK- 124
            FF+  +  G+  S    WR  RK++  +F   IL  FV IFN+ S  + + + S VG+ 
Sbjct: 107 DFFR--VSRGIFSSPAHIWRGQRKVLNHSFGPGILNCFVSIFNEKSEILTKLMTSHVGRG 164

Query: 125 TFDVHDYMSGTTVDILLETAMGISRKTQD-ESGFDYAMAVMKMCDIIHQRHYKFWMRSEI 183
             D    ++   +D +  TA G++   Q+   G  Y  A  +   ++ +R +     SE 
Sbjct: 165 ERDFGHEIARAALDTIYSTAFGLNFGMQEAPEGSKYLEAQEEFIGLVLKRIFSVINYSER 224

Query: 184 VFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLE 230
           +++LT  +K++ +LL     LTN++++ +    + + A G+   T E
Sbjct: 225 IYRLTKDYKREQELLSYARTLTNRIMQARNAEQILSGAIGLPSVTTE 271


>UniRef50_P13584 Cluster: Cytochrome P450 4B1; n=32;
           Euteleostomi|Rep: Cytochrome P450 4B1 - Homo sapiens
           (Human)
          Length = 511

 Score =  155 bits (376), Expect = 3e-36
 Identities = 79/231 (34%), Positives = 129/231 (55%), Gaps = 3/231 (1%)

Query: 267 VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326
           +  ++ L FLD+++ +      K+SD +++ EVDT MFEGHDTT +G S+ L  + ++ +
Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336

Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386
            Q R  +E+ +I GD D    + D  +M YL   I ES RLYPPVP + R+L++ VT   
Sbjct: 337 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-V 394

Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446
               +PAG+ + +  + LHR    + DPEVF+   F  EN   RH ++++PFSAGPR+C+
Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454

Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
           G+++A              F    +      K+   ++L+   GF + ++P
Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMP-QLVLRSKNGFHLHLKP 504



 Score = 95.1 bits (226), Expect = 4e-18
 Identities = 54/220 (24%), Positives = 103/220 (46%), Gaps = 6/220 (2%)

Query: 5   IHVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATE 64
           + +QE     K+V+    +A  F     +W G  +    +   D    + S         
Sbjct: 59  LEIQETGSLDKVVS----WAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDV 114

Query: 65  YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEV 122
           Y FF  W+G GLL+  GPKW  HRK++ P FH ++LK +V +F +++  +++K   K+  
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174

Query: 123 GKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSE 182
           GK+FD+   +    ++ L++   G            Y +AV  +  ++ QR   F   ++
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHND 234

Query: 183 IVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAK 222
            ++ LT   ++  +   + H  T++VI+ +K    + K +
Sbjct: 235 FIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVR 274


>UniRef50_UPI00015B5196 Cluster: PREDICTED: similar to cytochrome
           P450 CYP4C39; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4C39 - Nasonia vitripennis
          Length = 507

 Score =  154 bits (373), Expect = 6e-36
 Identities = 75/233 (32%), Positives = 132/233 (56%), Gaps = 5/233 (2%)

Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328
           EK +   L  ++ +  + TN++++ E+++E+ TI     DT A  SSF + +LGIH DVQ
Sbjct: 276 EKSKTCILHRLL-TVNSVTNELTEEELRDEIYTIYIASQDTLAVTSSFAVLMLGIHGDVQ 334

Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
            +   E+ ++ G  D         ++KYLE VI E+LRL+P  P++ R+LN ++ +   N
Sbjct: 335 KKARSEVDEVIGVGD--VNIESLSKLKYLEMVIKETLRLFPIAPLMVRQLNGELKLD--N 390

Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
            ++P    VVI  +  HR  K++++PE F P+ F  + T  RH Y++IPFS GP  C+G+
Sbjct: 391 SILPKDCQVVIAPYATHRSSKFWENPENFLPERFAIKETVKRHPYTFIPFSGGPMGCIGQ 450

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRV 501
           KYA            + +   S++  ++ KL+ DI ++   G+++ ++ R  +
Sbjct: 451 KYALTALKMILANILQKYVVESDVTLRDIKLKTDISIRSMNGYKISLQARTNI 503



 Score =  137 bits (331), Expect = 7e-31
 Identities = 75/261 (28%), Positives = 133/261 (50%), Gaps = 6/261 (2%)

Query: 3   LNIHVQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKA 62
           L    + + L +++V++   YA      +R+W+G  L V + +  DIE++LNS     K 
Sbjct: 58  LKFACEPDQLLERIVDVIAPYADV--TPMRLWMGPMLYVIITEPRDIEVVLNSQQATSKG 115

Query: 63  TEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV 122
           + Y+F  P++G GL+  SG  W++HRK+I+   +   L SF+  F++ S   V+KL+   
Sbjct: 116 SAYKFLYPFIGNGLISGSGKSWKAHRKIISHILNQRTLDSFIETFDRRSKEFVKKLEPLA 175

Query: 123 -GKTFDVHDYMSGTTVDILLETAMG---ISRKTQDESGFDYAMAVMKMCDIIHQRHYKFW 178
            G+ FD+   + G T+D++ ET MG   I+        F +  A  +M  IIH R  K W
Sbjct: 176 NGEVFDIFHSLEGCTIDLVCETVMGYTDINALDNPNKEFVHYTADFRMYKIIHNRMMKIW 235

Query: 179 MRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGE 238
           +  + +F++TS +  Q +   +IH  T + I+  ++  L+ K+K  I   L      + E
Sbjct: 236 LYPDWIFRITSNYSNQKRAQTMIHNFTERCIEAGRQDMLKEKSKTCILHRLLTVNSVTNE 295

Query: 239 ILANNAKTLSDTVFKGYRDDL 259
           +     +    T++   +D L
Sbjct: 296 LTEEELRDEIYTIYIASQDTL 316


>UniRef50_Q179B7 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 543

 Score =  154 bits (373), Expect = 6e-36
 Identities = 111/476 (23%), Positives = 224/476 (47%), Gaps = 23/476 (4%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86
           +  ++RVW G K+++F    D ++ +L S   ++K   Y F      +GL  S    WRS
Sbjct: 65  YDRMVRVWAGPKMLLFTSHPDLVQQLLTSPACLEKPFLYSF--AGFEQGLFTSKYKLWRS 122

Query: 87  HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL-KSEVGKTFDVHDYMSGTTVDILLETAM 145
            RK +  +F++ IL  F+ +F Q +  +VE L ++  G    +H + S  T+++   T +
Sbjct: 123 MRKRLNSSFNLRILHGFIPVFVQCARKMVEDLNENPDGTVVSMHKFTSVCTLEMACGTTL 182

Query: 146 GISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205
           G S  T+ E   ++   +        +R     +   IV+ LT + ++  +  G++    
Sbjct: 183 G-SDITRREGKEEFVHGLDIAFGEAARRMVSVHLYPNIVYHLTKYHRELVQARGVVCDFF 241

Query: 206 NKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLS-DTVFKGYRDDLDFNDE 264
           ++V        L     G+I   + +      +++     T+S +   K   ++LDF   
Sbjct: 242 SRV-------SLFPPFFGVIMSHIIDCCMFYFQLVTERRNTMSLNCNKKTNEEELDF--- 291

Query: 265 NDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324
               ++K    +D ++  +++G    SD EI++ +  ++   +DT+    +     L  +
Sbjct: 292 ----DRKPKILIDQLLSVNRDG-KSFSDTEIEDNIYAVITGANDTSGLLIAHACLFLCFY 346

Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384
           +D++ +++ E+ +   + +         ++ YLE+ + E LR  P  P I+R+   ++ I
Sbjct: 347 KDIEEKLFTEIMEFMPNEEFEINPESLKQLSYLEKFLKECLRHCPVAPNISRENMSEIEI 406

Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443
                 +P G   ++  + LHR+   +  D + F+P+ F  E ++NRH ++Y+PFS G R
Sbjct: 407 D--GMKVPPGNIFIMNFYALHRRKDIWGPDADKFDPEQFSEERSRNRHPFAYLPFSGGNR 464

Query: 444 SCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
            C+G +YA            RNF+  +EI  ++ + + D+ +K      +KV  RK
Sbjct: 465 ICIGWRYAMFSMKVMLIYLIRNFQFETEIRPEQVRYRHDLTMKLPFEHMIKVTRRK 520


>UniRef50_UPI0000F2BA18 Cluster: PREDICTED: similar to Cytochrome
           P450 4A2 precursor (CYPIVA2) (Lauric acid
           omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450
           K-2); n=1; Monodelphis domestica|Rep: PREDICTED: similar
           to Cytochrome P450 4A2 precursor (CYPIVA2) (Lauric acid
           omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450
           K-2) - Monodelphis domestica
          Length = 519

 Score =  153 bits (370), Expect = 1e-35
 Identities = 74/236 (31%), Positives = 130/236 (55%), Gaps = 3/236 (1%)

Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321
           ++++ V +KK L FLD++ ++        ++ E++ EV+T  F G DT A G S+ L  L
Sbjct: 285 SEKDKVPKKKYLNFLDILFQAKDEDGGGFTNEELENEVNTFRFAGQDTVAVGFSWTLYCL 344

Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381
            ++ + Q +  +E+  I  D +   T+    +M Y    I ES R+Y P+P +AR LN+ 
Sbjct: 345 AMNPEYQKKCREEIQGILKDGES-ITWDHLTQMTYSTMCIKESFRMYSPIPKVARTLNQP 403

Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441
           +T       +P+ TTV I  + LH  P  +++P+VF+P+ F PENT+ RH Y+++PFSAG
Sbjct: 404 ITFPD-GQTLPSDTTVTINIWALHYNPAIWENPKVFDPERFTPENTKKRHPYAFLPFSAG 462

Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
            R+C+G+++A              F  + ++ +    +   I+L+   GF   ++P
Sbjct: 463 LRNCIGQQFAMNLIKVSLALTLLRFELLPDLEKPPIPI-SQIVLRSTSGFHFYLKP 517



 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 44/157 (28%), Positives = 81/157 (51%), Gaps = 4/157 (2%)

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV---EKLKSEVGKTFDVH 129
           G+GLL   G KW  HR+++ P FH NILK ++ I     + ++   EKL+++   + DV 
Sbjct: 136 GKGLLSLEGEKWHYHRRLLTPAFHFNILKDYIYIMRNTVSLMLDKWEKLRTK-DSSIDVF 194

Query: 130 DYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTS 189
           D++S  ++D  L+   G+    ++ES F Y   + K+  ++ +R   F   S+ ++KLTS
Sbjct: 195 DFISYMSLDTSLKATFGLQDFNKEESLFSYFQNMNKLLYLVRKRMETFLYYSDFIYKLTS 254

Query: 190 FFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIP 226
              +       +     K+I++++  Y     K  +P
Sbjct: 255 DHYEFQTTCKELKEEPAKIIRHRRALYKNQSEKDKVP 291


>UniRef50_UPI0000D9991B Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily A, polypeptide 11 isoform 1;
           n=3; Catarrhini|Rep: PREDICTED: similar to cytochrome
           P450, family 4, subfamily A, polypeptide 11 isoform 1 -
           Macaca mulatta
          Length = 487

 Score =  152 bits (369), Expect = 2e-35
 Identities = 80/229 (34%), Positives = 127/229 (55%), Gaps = 5/229 (2%)

Query: 267 VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326
           V  KK L FLD+++ +     + +SD +++ EVDT MFEGHDTTA+G S++L  L  H  
Sbjct: 251 VKRKKHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPK 310

Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386
            Q R  +E++ + GD     T+    +M Y    I E+LRLYPPVP I+R+L+  VT   
Sbjct: 311 HQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGISRELSTPVTF-P 368

Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446
               +P G TV++  + LH  PK + +PEVF+P  F P + Q  H ++++PFS G R+C+
Sbjct: 369 DGRSLPKGITVMLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQ--HSHAFLPFSGGSRNCI 426

Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKV 495
           G+++A              F  + + P +       ++LK   G  +++
Sbjct: 427 GKQFAMNELKVATALTLLRFELLPD-PTRIPIPMARLVLKSKNGIHLRL 474



 Score = 80.6 bits (190), Expect = 9e-14
 Identities = 49/170 (28%), Positives = 84/170 (49%), Gaps = 5/170 (2%)

Query: 6   HVQEENLTQKLVNLALGYAQTFGNVIRVWL-GSKLIVFLVDADDIEIILNSHVHIDKATE 64
           H QE    Q+L  +   + + F +   +WL G K  V L D D +++IL           
Sbjct: 62  HKQEFQQDQELQRIRK-WVEMFPSACPLWLWGGKARVQLHDPDYMKVILGRS-DPKSQDP 119

Query: 65  YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK 124
           YRF  PW+G GLL+ +G  W  HR+M+ P FH +ILK++V +   +   +++K +  +G+
Sbjct: 120 YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKAYVALMADSVRVMLDKWEKLLGQ 179

Query: 125 --TFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQ 172
               +V  ++S  T+D +++ A       Q +S         + C + HQ
Sbjct: 180 DSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDSLTSTGRWTHRACQLAHQ 229


>UniRef50_UPI0000D56470 Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=5; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 495

 Score =  150 bits (364), Expect = 7e-35
 Identities = 86/237 (36%), Positives = 136/237 (57%), Gaps = 9/237 (3%)

Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321
           +DEN   +KKR  FL+ ++ +S+    +I +  I EE+ TI+  G +TTA     V  +L
Sbjct: 262 DDENY--KKKR--FLNHLLTTSETNP-QIDELAILEEIQTILVTGSETTAITIGMVFIIL 316

Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381
           GI+ ++Q +V  EL  I G  DR  T  D   ++YLERVI E+LR+ P VP+I R + +D
Sbjct: 317 GIYPEIQEKVRSELELILGPDDREITLEDINNLEYLERVIKETLRVLPIVPLITRTVEQD 376

Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441
           V + TK   IP+G+ V++    + ++ +++ +P+ F+PD FLPEN  NR   S+IPFS G
Sbjct: 377 VKLGTK--TIPSGSFVLVPIASIGKKAEFWAEPKKFDPDRFLPENNANRPRCSFIPFSYG 434

Query: 442 PRSCVGRKYAXXXXXXXXXXXXR--NFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496
           PR+C+G KY             R   F+       ++ +L   ++ K   GF++K+E
Sbjct: 435 PRNCIGFKYGMMSLKVLLATVIRKFTFKPSQYRRIEDVRLIYGMVAKPKHGFKVKIE 491



 Score = 94.3 bits (224), Expect = 7e-18
 Identities = 56/199 (28%), Positives = 100/199 (50%), Gaps = 8/199 (4%)

Query: 25  QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKW 84
           +T  +V + WLG  L+V     +D+EI+LN++    K   Y F       GLLI+    W
Sbjct: 71  ETQPSVFKFWLGKDLLVVTSKPEDVEIVLNNNSCFGKPKFYDFAFKLFRNGLLIAPASIW 130

Query: 85  RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETA 144
           R  R++I PTF+  IL SF+ IF ++ N +V+ L+    ++ D+   +   T DI  ET 
Sbjct: 131 RDRRRVINPTFNPKILNSFIEIFGKHGNKLVKVLEESCSES-DIFLKLFRCTFDIACETL 189

Query: 145 MGISR---KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGII 201
             +     K QD+    Y   V++M DI+  R +  W+  + ++K + + K+  K    +
Sbjct: 190 ADVDSELIKGQDK----YLQTVIRMEDILAIRSFSIWLHPDFLWKRSFYGKEMEKASAEV 245

Query: 202 HGLTNKVIKNKKETYLENK 220
                +++  KK +  +++
Sbjct: 246 FAFVKQILALKKASVTDDE 264


>UniRef50_Q6TGT4 Cluster: Thromboxane A synthase 1; n=6; cellular
           organisms|Rep: Thromboxane A synthase 1 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 546

 Score =  148 bits (359), Expect = 3e-34
 Identities = 113/484 (23%), Positives = 216/484 (44%), Gaps = 28/484 (5%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHI--DKATEYRFFKPWLGEGLLISSGPKW 84
           +G +   ++G +  V + D D +  ++    +   ++ T     KP + + L++  G +W
Sbjct: 78  YGRICGYYIGRRSTVIIADPDMLRQVMVKEFNKFPNRMTARGITKP-MSDSLIMLKGEQW 136

Query: 85  RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS--EVGKTFDVHDYMSGTTVDILLE 142
           +  R ++ PTF    +K  V + N  +  ++  LKS  E   +F++H      T+D++  
Sbjct: 137 KRVRSILTPTFSAAKMKEMVPLINTATETLLRNLKSHAESENSFNIHKCFGCFTMDVIAS 196

Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYK-FWMRSEIVFK-LTSFF--KQQTKLL 198
            A G    +Q+     +     K       R    F+M    + + L      K + ++ 
Sbjct: 197 VAFGTQVDSQNNPDDPFVHQASKFFAFSFFRPIMIFFMAFPFLLRPLAGLLPNKSRDEMN 256

Query: 199 GIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDD 258
                   K+IK + +   E + K  +   L+  T++   +   +   ++D   + Y   
Sbjct: 257 SFFTQCIQKMIKQRDDLSPEQRRKDFLQLMLDVRTNNKF-LSVEHFDVVNDADEEAY--- 312

Query: 259 LDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318
            D ++ +   E  +         S Q     +++ EI  +    +  G++T++   +F  
Sbjct: 313 -DGHENSPANESTK--------RSQQK--RMMTEDEIVGQSFIFLVAGYETSSNTLAFTC 361

Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKL 378
            LL +H + Q ++ +E+ + F   +    +A+  E+KYL+ VI ESLRLYPP   +AR +
Sbjct: 362 YLLAVHPECQKKLQEEVDEFFSRHEM-VDYANVQELKYLDMVICESLRLYPPAFRVARDV 420

Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPF 438
             D  ++ +   +P G ++ I T  LH  P+++ +P  F P+ F PE    RH + Y+PF
Sbjct: 421 EEDTVLNGQ--FLPKGASLEIPTGFLHYDPEHWTEPTKFIPERFTPEAKARRHPFVYLPF 478

Query: 439 SAGPRSCVGRKYAXXXXXXXXXXXXRNFRTIS-EIPEKEFKLQGDIILKRAEGFQMKVEP 497
            AGPRSCVG + A            R F  ++ E  E   +L+    L    G  +K+  
Sbjct: 479 GAGPRSCVGMRLAQLEIKVALVHIFRRFNVLACEDTEIPLELKSHTTLGPKNGVMVKITE 538

Query: 498 RKRV 501
           R+ +
Sbjct: 539 RENL 542


>UniRef50_Q6PW73 Cluster: Cytochrome P450 CYP4AT1; n=1; Capitella
           capitata|Rep: Cytochrome P450 CYP4AT1 - Capitella
           capitata
          Length = 490

 Score =  147 bits (357), Expect = 5e-34
 Identities = 84/250 (33%), Positives = 138/250 (55%), Gaps = 5/250 (2%)

Query: 248 SDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGH 307
           SD+  +G R++   +  N V + + L FLD+++++  +    ++D EI+ EVDT MFEGH
Sbjct: 244 SDSRQEG-REEKKRSRRNQV-DSQNLDFLDILLDAKDSDGRGLTDEEIQHEVDTFMFEGH 301

Query: 308 DTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRL 367
           DTTA+G S+ L  L  H + Q R   E+  + GD      + D  ++ +L   I ESLRL
Sbjct: 302 DTTASGLSWCLYNLARHPEYQDRCRKEVMDVMGDRS-DVEWDDMSKLTFLTMCIKESLRL 360

Query: 368 YPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENT 427
           +P VP I R L + +T       +PA T + I  +  H     +++PE ++P+ F  EN+
Sbjct: 361 HPAVPNIGRSLTKPMTF-PDGRTVPAETDLGIAIYGCHHNSALWENPEQYDPERFNAENS 419

Query: 428 QNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKR 487
           ++R  +S+IPFSAGPR+C+G+ +A            +NF+   +   +  +L   ++LK 
Sbjct: 420 KDRPPHSFIPFSAGPRNCIGQHFAMHEMRSVLAVCLKNFQLRID-DTRILELLPQLVLKA 478

Query: 488 AEGFQMKVEP 497
             G  +KV P
Sbjct: 479 KGGLWLKVTP 488



 Score = 85.0 bits (201), Expect = 4e-15
 Identities = 47/180 (26%), Positives = 96/180 (53%), Gaps = 5/180 (2%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82
           +++ F  +    +G  + + L     +  +L++    D+ + YR  KPW+G+GLL+SSG 
Sbjct: 56  WSELFDGLFSYCIGLYVCMELSHPSPLSKLLSTAEPKDRIS-YRTIKPWIGDGLLVSSGE 114

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT---FDVHDYMSGTTVDI 139
           KW  +R+++ P FH ++LK +VGIF+  +N + +K +  + K     ++  ++S  T+D 
Sbjct: 115 KWARNRRLLTPAFHFDVLKPYVGIFSSTANIMADKWRKILSKNDEPLEMFQHVSLMTLDS 174

Query: 140 LLETAMGISRKTQDES-GFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLL 198
           LL+   G +   Q+E     Y  +V ++ +++ +R   F    + ++  T    Q + +L
Sbjct: 175 LLKCIFGQTGSVQNEGRDGSYIRSVYQLTELVMKRFQFFPYLIDWIYYFTPSALQVSPML 234


>UniRef50_Q02928 Cluster: Cytochrome P450 4A11 precursor; n=114;
           Tetrapoda|Rep: Cytochrome P450 4A11 precursor - Homo
           sapiens (Human)
          Length = 519

 Score =  147 bits (355), Expect = 9e-34
 Identities = 76/229 (33%), Positives = 124/229 (54%), Gaps = 5/229 (2%)

Query: 267 VGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326
           +  K+ L FLD+++ +     + +SD +++ EVDT MFEGHDTTA+G S++L  L  H  
Sbjct: 283 IKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPK 342

Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386
            Q R  +E++ + GD     T+    +M Y    I E+LRLYPPVP I R+L+  VT   
Sbjct: 343 HQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF-P 400

Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446
               +P G  V++  + LH  PK + +PEVF+P  F P + Q  H ++++PFS G R+C+
Sbjct: 401 DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRNCI 458

Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKV 495
           G+++A              F  + +       +   ++LK   G  +++
Sbjct: 459 GKQFAMNELKVATALTLLRFELLPDPTRIPIPI-ARLVLKSKNGIHLRL 506



 Score = 97.9 bits (233), Expect = 6e-19
 Identities = 59/212 (27%), Positives = 111/212 (52%), Gaps = 6/212 (2%)

Query: 6   HVQEENLTQKLVNLALGYAQTFGNVIRVWL-GSKLIVFLVDADDIEIILNSHVHIDKATE 64
           H+QE    Q+L  +   + +TF +    WL G K+ V L D D +++IL         + 
Sbjct: 62  HIQELQQDQELQRIQK-WVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS- 119

Query: 65  YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK 124
           YRF  PW+G GLL+ +G  W  HR+M+ P FH +ILK +VG+   +   +++K +  +G+
Sbjct: 120 YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQ 179

Query: 125 --TFDVHDYMSGTTVDILLETAMGISRKTQ-DESGFDYAMAVMKMCDIIHQRHYKFWMRS 181
               +V  ++S  T+D +++ A       Q D +   Y  A+  + +++  R    + ++
Sbjct: 180 DSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQN 239

Query: 182 EIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213
           + ++ LTS  +   +   + H  T++VI+ +K
Sbjct: 240 DTIYSLTSAGRWTHRACQLAHQHTDQVIQLRK 271


>UniRef50_Q9VG40 Cluster: Probable cytochrome P450 313a4; n=3;
           Sophophora|Rep: Probable cytochrome P450 313a4 -
           Drosophila melanogaster (Fruit fly)
          Length = 478

 Score =  145 bits (352), Expect = 2e-33
 Identities = 73/214 (34%), Positives = 125/214 (58%), Gaps = 5/214 (2%)

Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           FL+L+ +  + G   + +  +++E + I+F   +TTA    + L LL +  + Q R ++E
Sbjct: 255 FLNLVTDLMRRGVFTLKN--VEDESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEE 312

Query: 335 LYQIFGDS-DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPA 393
           +  IF ++ D   ++ADT +M YL+ ++ ES+R+ PPVPV++R+ ++D+ +S    V+P 
Sbjct: 313 IKTIFPNTGDFDVSYADTQQMVYLDLILNESMRVIPPVPVVSRQTSQDLKLSN-GIVVPK 371

Query: 394 GTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 452
           G  + I  + +HR  K +  D E FNPD+FLP N Q++H Y+YIPF+ G R+C+G +YA 
Sbjct: 372 GVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQDKHPYAYIPFTKGIRNCIGWRYAL 431

Query: 453 XXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486
                      RN+R  +  P +      DI +K
Sbjct: 432 ISAKVTLAKLLRNYRFKTSFPFENLYFVEDITMK 465



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 5/132 (3%)

Query: 28  GNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSH 87
           G  I  WLG    + + D   ++ I  S   ++K   Y+      G GL     P+W  H
Sbjct: 65  GPTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAGVGLFSLKDPRWSIH 124

Query: 88  RKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAM 145
           RK++ P F   +L SF+ IFN+ +  ++++L+   + G+  D+   +   T+ I  +T M
Sbjct: 125 RKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEK-DLIPLLQSFTLGIATQTTM 183

Query: 146 GISRKTQDESGF 157
           G   K  DE  F
Sbjct: 184 GSDVK--DEESF 193


>UniRef50_Q4U3Y4 Cluster: CYP325C2; n=4; Anopheles gambiae|Rep:
           CYP325C2 - Anopheles gambiae (African malaria mosquito)
          Length = 264

 Score =  144 bits (350), Expect = 4e-33
 Identities = 78/230 (33%), Positives = 126/230 (54%), Gaps = 4/230 (1%)

Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329
           KK L F D ++ +  NG N  +D E+   + +++  G+DTTA   +     L +H  +Q 
Sbjct: 37  KKPLIFADQLLAAQHNG-NPFTDIEVTHNIYSMIAAGNDTTALQVTHTCLFLAMHPAIQE 95

Query: 330 RVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389
           RVY E+  +F D D+     D  ++ Y+ERVI ESLRL P  P IAR+  +D+ I+  + 
Sbjct: 96  RVYREVMDVFPDPDQDIEVEDLKKLTYMERVIKESLRLAPSGPNIARQTMKDIEIAGVH- 154

Query: 390 VIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
            IP  + +V+  F +HR+   +  D ++F+PD FLPE ++ R    +IPFSAG R+C+G 
Sbjct: 155 -IPRDSLIVMSIFSMHRRKDIWGPDADLFDPDRFLPERSEGRSTNVFIPFSAGSRNCIGG 213

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           +YA            R  R  S++   + + + D+ LK    + ++VE R
Sbjct: 214 RYAMLSMKVMLSSILRRLRLRSDLQMNDLQFRFDLTLKLESEYFVQVEKR 263


>UniRef50_Q16L50 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 428

 Score =  144 bits (350), Expect = 4e-33
 Identities = 79/240 (32%), Positives = 130/240 (54%), Gaps = 4/240 (1%)

Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319
           D+ D+ DVG KK   F++ +++  Q  +  I   +I + + T+ F G+DTTA   S +L 
Sbjct: 192 DYQDK-DVGAKKIPIFVEKLLDEIQK-SGHIKREDIDDHIVTMCFAGNDTTATTMSNILL 249

Query: 320 LLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLN 379
           +L +H D+Q RVY E+     D ++  +  D  ++ Y E V  E++R +   PVI R   
Sbjct: 250 MLAMHPDIQERVYQEIIAACPDRNQQVSIEDAGKLTYTEMVCKETMRHFSIAPVIGRTAT 309

Query: 380 RDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPF 438
           +DV ++  +  IPA +T++   + LH  PK +  D + FNPDNFLP+    RH YS++PF
Sbjct: 310 QDVKLN-DDITIPANSTLICCFYKLHMDPKNWGPDVKNFNPDNFLPDLVAKRHPYSFLPF 368

Query: 439 SAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           S GPR+C+G +YA            R +R  + +      ++ +  +K  +G  + VE R
Sbjct: 369 SGGPRNCLGVRYAWLSMKIMLVHILRRYRLRTTLTMDTITVKFNSFMKIEDGCPITVEER 428



 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 48/173 (27%), Positives = 90/173 (52%), Gaps = 8/173 (4%)

Query: 35  LGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPT 94
           +G  + +F+   + ++++LNS   ++K  +Y FF+  +  G+  +    W+  RK+I P+
Sbjct: 1   MGPMVYIFVYTPEQLQVVLNSPHCLEKPLQYSFFQ--VSRGIFSAPVDLWKILRKLITPS 58

Query: 95  FHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRKTQ- 152
           F   +L SFV IFN+ S+ +VE++   VGK   D +  +    +D +  TA G+    Q 
Sbjct: 59  FGPGLLSSFVPIFNEKSSVMVEQMAKNVGKPQRDYYSEIVLCFMDTICNTAFGVDCDLQR 118

Query: 153 DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTS----FFKQQTKLLGII 201
             +G +Y     K  DI+ +R+ K W     +++ T+    F K+  K L ++
Sbjct: 119 SPAGAEYVETQEKYIDIVTERYLKPWQYLNFIYRFTNAYQIFKKRHGKFLALL 171


>UniRef50_Q8N118 Cluster: Cytochrome P450 4X1; n=12; Mammalia|Rep:
           Cytochrome P450 4X1 - Homo sapiens (Human)
          Length = 509

 Score =  144 bits (350), Expect = 4e-33
 Identities = 80/250 (32%), Positives = 130/250 (52%), Gaps = 4/250 (1%)

Query: 248 SDTVFKGYRDDLDFNDENDVGEKKRLA-FLDLMIESSQNGTNKISDHEIKEEVDTIMFEG 306
           +DT+ +  +  L    + D   K++   FLD+++ +     +  SD ++  EV T +  G
Sbjct: 258 TDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAG 317

Query: 307 HDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLR 366
           HDT AA  S++L  L ++ + Q R  +E+  I GD     T+    EM Y    I E+ R
Sbjct: 318 HDTLAASISWILYCLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCR 376

Query: 367 LYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPEN 426
           L P VP I+R L++ +T       +PAG TVV+  + LH  P  +K+P+VF+P  F  EN
Sbjct: 377 LIPAVPSISRDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQEN 435

Query: 427 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486
           +  RH Y+Y+PFSAG R+C+G+++A             +FR ++  P +        ILK
Sbjct: 436 SDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFR-VTPDPTRPLTFPNHFILK 494

Query: 487 RAEGFQMKVE 496
              G  + ++
Sbjct: 495 PKNGMYLHLK 504



 Score = 95.9 bits (228), Expect = 2e-18
 Identities = 60/216 (27%), Positives = 115/216 (53%), Gaps = 15/216 (6%)

Query: 7   VQEENLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLV-DADDIEIILNSHVHIDKATEY 65
           +Q++N+ +KL  +   Y + F      W+G     F + D D  + +L+     D  ++Y
Sbjct: 61  IQDDNM-EKLEEIIEKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQY 112

Query: 66  --RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV---EKLKS 120
             +F  P LG+GL    GPKW  HR+++ P FH NILK+++ +   +   ++   EK+ S
Sbjct: 113 LQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICS 172

Query: 121 EVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFD-YAMAVMKMCDIIHQRHYKFWM 179
               + +V+++++  ++DI+++ A       Q  S  D YA A+ ++  II  R Y    
Sbjct: 173 TQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLY 232

Query: 180 RSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKET 215
            S+I+FKL+    +  KL  +++  T+ +I+ +K++
Sbjct: 233 HSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKS 268


>UniRef50_Q6NT55 Cluster: Cytochrome P450 4F22; n=127;
           Deuterostomia|Rep: Cytochrome P450 4F22 - Homo sapiens
           (Human)
          Length = 531

 Score =  144 bits (349), Expect = 5e-33
 Identities = 72/228 (31%), Positives = 125/228 (54%), Gaps = 3/228 (1%)

Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330
           K L F+D+++ +      ++SD +I+ E DT MFEGHDTT++G S++L  L  + + Q +
Sbjct: 301 KTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEK 360

Query: 331 VYDELYQIF-GDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389
             +E+ ++  G       + D  ++ +    I ESLR YPPV +++R+   D+ +     
Sbjct: 361 CREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGR- 419

Query: 390 VIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449
           +IP G   ++  +  H  P  + D +V+NP  F P+N Q R   +Y+PFSAGPR+C+G+ 
Sbjct: 420 IIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQS 479

Query: 450 YAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
           +A              FR +S    ++ + + ++IL+   G  +KVEP
Sbjct: 480 FAMAELRVVVALTLLRFR-LSVDRTRKVRRKPELILRTENGLWLKVEP 526



 Score = 99.1 bits (236), Expect = 2e-19
 Identities = 55/200 (27%), Positives = 109/200 (54%), Gaps = 7/200 (3%)

Query: 29  NVIRVWLGSKL-IVFLVDADDIEIILNSHVHIDKATE--YRFFKPWLGEGLLISSGPKWR 85
           +V+ VW+G  L ++ LV  D I+ +L +   I    +  Y F KPWLG+GLL+S G KW 
Sbjct: 94  HVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153

Query: 86  SHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTTVDILLE 142
            HR+++ P FH +ILK ++ IFNQ+++ +  K   L      + D+ +++S  T+D L +
Sbjct: 154 RHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQK 213

Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202
                +   Q++   DY  A++++  +  +R Y+     + ++  ++  ++  +   ++H
Sbjct: 214 CVFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVH 272

Query: 203 GLTNKVIKNKKETYLENKAK 222
             T +VI+ ++    +  A+
Sbjct: 273 HFTTEVIQERRRALRQQGAE 292


>UniRef50_Q6SPQ6 Cluster: CYP4BB1; n=2; Protostomia|Rep: CYP4BB1 -
           Nereis virens (Sandworm)
          Length = 508

 Score =  144 bits (348), Expect = 6e-33
 Identities = 80/254 (31%), Positives = 134/254 (52%), Gaps = 6/254 (2%)

Query: 247 LSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEG 306
           +++TV    R+ L  N +  + ++K L FLD+++++       +SD EI+ EVDT MFEG
Sbjct: 259 VAETVISQRRETLQENPDA-LEDRKYLDFLDILLQARDEDGTGLSDLEIRNEVDTFMFEG 317

Query: 307 HDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTL-EMKYLERVILESL 365
           HDTTA+G S+ L  L  H + Q +   E+ ++  D        D L ++ YL   + ES+
Sbjct: 318 HDTTASGISWALYSLAKHPEFQKKAQQEIDELLADRKNKWIMWDDLNQLPYLTMCLKESM 377

Query: 366 RLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLP 424
           RL+ PVPVI+R+L   +TI      +P  T   I    LH  P  + +D + + P+ FLP
Sbjct: 378 RLWCPVPVISRQLLNPITID--GVTLPPHTLFDINIIALHHNPTVWGEDHDEYKPERFLP 435

Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDII 484
           EN      ++++PFSAGPR+C+G+ +A            + F  +S         + +++
Sbjct: 436 ENINKMDNFAFLPFSAGPRNCIGQNFAFNEMKTTIARIIQRF-DLSVDESHPVYPRPEVV 494

Query: 485 LKRAEGFQMKVEPR 498
            +   G ++ + PR
Sbjct: 495 TRAIHGIKLFMNPR 508


>UniRef50_Q8K4D6 Cluster: Cytochrome P450 4X1; n=15; Eutheria|Rep:
           Cytochrome P450 4X1 - Rattus norvegicus (Rat)
          Length = 507

 Score =  143 bits (347), Expect = 8e-33
 Identities = 69/198 (34%), Positives = 116/198 (58%), Gaps = 2/198 (1%)

Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           FLD+++ +        SD +++ EV+T M+ GHD +AA  S++L  L ++ + Q R   E
Sbjct: 284 FLDIVLSAQAGDEKAFSDADLRSEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTE 343

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           +  I GD     T+    E+ Y    I E+LRL PP+P I+R+L++ +T+    + +PAG
Sbjct: 344 IRSILGDGSS-ITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSKPLTLPD-GHSLPAG 401

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454
            TVV+  + LH  P  +KDP+VF+P  F  EN++ RH  +++PFS+GPR+C+G+++A   
Sbjct: 402 MTVVLSIWGLHHNPAVWKDPKVFDPLRFTKENSEQRHPCAFLPFSSGPRNCIGQQFAMLE 461

Query: 455 XXXXXXXXXRNFRTISEI 472
                      FR  +++
Sbjct: 462 LKVAIALTLLRFRVAADL 479



 Score = 97.9 bits (233), Expect = 6e-19
 Identities = 72/250 (28%), Positives = 124/250 (49%), Gaps = 16/250 (6%)

Query: 7   VQEENLTQKLVNLALGYAQTFGNVIRVWLGS-KLIVFLVDADDIEIILNSHVHIDKATEY 65
           +QE+N+ +KL  +   Y   F      W+G  +   ++ D D  +I L+     D  T+Y
Sbjct: 61  LQEDNM-EKLDEIVKEYPCAFP----CWVGPFQAFFYIYDPDYAKIFLS---RTDPKTQY 112

Query: 66  --RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV---EKLKS 120
             +   P+LG GLL   GP+W  HR ++ P FH +ILK  V +   + N ++   EK  +
Sbjct: 113 LHQLMTPFLGRGLLNLDGPRWFQHRCLLTPAFHQDILKPCVDMMAHSVNMMLDKWEKTWT 172

Query: 121 EVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFD-YAMAVMKMCDIIHQRHYKFWM 179
               T +V ++++  T+DI+++ A G     Q    ++ Y  A  ++ +II  R Y FW 
Sbjct: 173 TQETTIEVFEHINLMTLDIIMKCAFGQETNCQINGTYESYVKATFELGEIISSRLYNFWH 232

Query: 180 RSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEI 239
             +I+FKL+       +L  +IH  T K+I+++K+T L+++       T + F       
Sbjct: 233 HHDIIFKLSPKGHCFQELGKVIHQCTEKIIQDRKKT-LKDQVNQDDTQTSQNFLDIVLSA 291

Query: 240 LANNAKTLSD 249
            A + K  SD
Sbjct: 292 QAGDEKAFSD 301


>UniRef50_Q5XM61 Cluster: Cytochrome P450; n=9; Pancrustacea|Rep:
           Cytochrome P450 - Anopheles gambiae (African malaria
           mosquito)
          Length = 147

 Score =  142 bits (345), Expect = 1e-32
 Identities = 70/138 (50%), Positives = 94/138 (68%), Gaps = 4/138 (2%)

Query: 267 VGEKKRLAFLDLMIESSQNGTNK--ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324
           +G +KRLAFLDL+++S+  GT    ++D +++EEVDT MFEGHDTT AG S+ L LL +H
Sbjct: 10  LGRRKRLAFLDLLLQSATTGTGSPLLTDEDVREEVDTFMFEGHDTTTAGMSWALFLLALH 69

Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384
            +VQ RV+ E+  IFG SDRPAT  D   M+ LER + E+LRLYP V    R  ++DVT+
Sbjct: 70  PEVQERVHQEIDSIFGGSDRPATMQDLTAMRLLERCLKETLRLYPSVAFFGRTTSKDVTL 129

Query: 385 STKNYVIPAGTTVVIGTF 402
               Y +PAGT V I  +
Sbjct: 130 G--GYHVPAGTIVGIHAY 145


>UniRef50_Q5V5P9 Cluster: Cytochrome P450; n=3;
           Halobacteriaceae|Rep: Cytochrome P450 - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 445

 Score =  142 bits (345), Expect = 1e-32
 Identities = 75/213 (35%), Positives = 119/213 (55%), Gaps = 8/213 (3%)

Query: 257 DDLDFNDENDVG--EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGS 314
           DD+    E+ +G  E   + FL +++ +  +G    S  ++++E+ T++  GHDTTA   
Sbjct: 209 DDIIEVREDSLGTDEDGPMDFLSVLLRARDDGNQ--SPEQLRDEMMTMLLAGHDTTALTL 266

Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374
           ++   LL  H +V+ RV++EL  + GD DRP       E+ YLE VI E++RLYPPV  I
Sbjct: 267 TYTWFLLSEHPEVEQRVHEELDDVIGD-DRPG-MEHVRELDYLEWVIQEAMRLYPPVYTI 324

Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434
            R+   DVT+S   Y + AGTT+++  + +HR  ++Y DPE F+P+ + PE    R  ++
Sbjct: 325 FREPTEDVTLS--GYEVEAGTTLMVPQWGVHRSERFYDDPETFDPERWKPERASERPRFA 382

Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467
           Y PF  GPR C+G+  A              +R
Sbjct: 383 YFPFGGGPRHCIGKHLAMLEAQLITATTASQYR 415



 Score = 50.4 bits (115), Expect = 1e-04
 Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 6/131 (4%)

Query: 25  QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYR--FFKPWLGEGLLISSGP 82
           + +G+V R  +G    V L D   IE +L S     +  +++       LG+GLL+S G 
Sbjct: 33  RAYGDVARFDMGPMDTVMLCDPTAIERVLVSEADRFRKPDFQGDALGDLLGDGLLLSEGE 92

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTVDILL 141
            W   RK+  P F +  L    G+ ++ + +  +++     G   D    M+  T+D++L
Sbjct: 93  TWEQQRKLANPAFSMARLS---GMADRITGHAEDRIADWSHGDVIDAEQSMTRVTLDVIL 149

Query: 142 ETAMGISRKTQ 152
           +  MG+    Q
Sbjct: 150 DLMMGVELSEQ 160


>UniRef50_Q8WQN5 Cluster: Cytochrome P450 CYP4H14; n=22;
           Endopterygota|Rep: Cytochrome P450 CYP4H14 - Anopheles
           gambiae (African malaria mosquito)
          Length = 151

 Score =  142 bits (343), Expect = 3e-32
 Identities = 66/153 (43%), Positives = 96/153 (62%), Gaps = 4/153 (2%)

Query: 298 EVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPA--TFADTLEMK 355
           EVDT MFEGHDTT +G SF +  L  + DVQ RVY+E+  I G   + A  T+ +  E K
Sbjct: 1   EVDTFMFEGHDTTTSGISFTIYELARNPDVQERVYEEIVSILGKDHKTAELTYQNLQEFK 60

Query: 356 YLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPE 415
           YL+ V+ E LR+YPPV +I R L  D+ ++     +PAG  V++  +++HR P+ Y +P 
Sbjct: 61  YLDLVVKEGLRMYPPVGIIGRALVEDLELN--GTTVPAGQNVLVPIYVIHRNPEIYPNPN 118

Query: 416 VFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
            F+P  F  +    R  + Y+PFSAGPR+C+G+
Sbjct: 119 QFDPSRFAEDAESKRGPFDYLPFSAGPRNCIGQ 151


>UniRef50_Q176V3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 498

 Score =  141 bits (341), Expect = 5e-32
 Identities = 118/459 (25%), Positives = 210/459 (45%), Gaps = 48/459 (10%)

Query: 32  RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLIS-SGPKWRSHRKM 90
           ++ LG K ++ +   D ++ +L  +   DK   Y F +  LG GL+   SG +W   RK+
Sbjct: 70  KLMLGPKPLITISHPDLMQQVLTRNDLYDKPFLYEFLR--LGNGLITERSGERWLQTRKL 127

Query: 91  IAPTFHINILKSFVGIFNQNSNNVVEKLKS--EVGKTFDVHDYMSGTTVDILLETAMGIS 148
           + PTF+ ++L SF+   +  +  +V KL+S  +     D++ ++   T    LE A+  +
Sbjct: 128 LGPTFNTSMLTSFLSTMDARTMKMVSKLQSLADGHSEIDIYPFLLTCT----LEIAISTT 183

Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKV 208
               D+             ++  Q+ Y        +  L  F K   + L  ++     +
Sbjct: 184 MGRMDD-------------EMPGQQDY--------IRNLEIFLKAVGERLVNVYYFIEPI 222

Query: 209 IKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVG 268
            K  K   + ++A+ I      EFTH          + +S   F+      DF  +++  
Sbjct: 223 YKLSKAYKIHDEARRIC----NEFTH----------RIVSKRRFEIQSLGEDFQQKDEY- 267

Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328
            K+ L  LD +I   +      SD E+ E + T++  G DT+A   ++    L ++ +VQ
Sbjct: 268 IKQHLNALDQIITMKRPDGTGFSDLEVNEHLYTLIGAGTDTSALNVAYTCLYLAMYPEVQ 327

Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
            +V  E+ Q+F   +      +  +++Y E VI E LRL+P VP+ AR+      I    
Sbjct: 328 EKVLTEINQVFYSPEVEVNIENLKQLEYTEMVIKEILRLFPAVPLGARQTMS--AIELDG 385

Query: 389 YVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447
             IP    ++   F LHR+   +  DPE F+P+ F PE  + RH ++Y+PFS G R+C+G
Sbjct: 386 IRIPKDQIIIFSMFTLHRRKDIWGPDPEQFDPERFRPEAIEARHPFAYLPFSGGLRNCIG 445

Query: 448 RKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486
            +YA            + F   + +   + KL+ ++ LK
Sbjct: 446 HRYAMNVMRIILLRIMQKFEIQTNMKPTDLKLKFEVTLK 484


>UniRef50_UPI0000D56469 Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily v, polypeptide 2; n=1;
           Tribolium castaneum|Rep: PREDICTED: similar to
           cytochrome P450, family 4, subfamily v, polypeptide 2 -
           Tribolium castaneum
          Length = 392

 Score =  140 bits (340), Expect = 6e-32
 Identities = 68/158 (43%), Positives = 103/158 (65%), Gaps = 3/158 (1%)

Query: 295 IKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEM 354
           I+EE+ TI+    ++TA     +L +LGI+ ++Q +V  EL  IFG  DR  T  D  +M
Sbjct: 187 IEEELQTILITSSESTALTVGMILTVLGIYPEIQKKVSKELDSIFGHDDRETTLEDVQKM 246

Query: 355 KYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDP 414
           KYLE VI E+ R+ P VP++AR  ++D+ +   NY IPAG+ +VI  + + +   ++K+P
Sbjct: 247 KYLECVIKETSRVLPAVPLLARLADKDIKLD--NYTIPAGSIIVIPIWQIGKNADFWKNP 304

Query: 415 EVFNPDNFLPENTQ-NRHYYSYIPFSAGPRSCVGRKYA 451
           + F+PD FLPEN   NR   S+IPFS GPR+C+G +Y+
Sbjct: 305 KKFDPDRFLPENCDPNRPRSSFIPFSYGPRNCIGFQYS 342



 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 2/95 (2%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           + + WLG  L+V      D+EIILN+    +K   Y F     G GLL +    W+  RK
Sbjct: 77  IFKFWLGQDLVVATSRLKDVEIILNNC--FEKPKFYNFMCEVTGNGLLTARENIWKERRK 134

Query: 90  MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK 124
           MI   F + +L S+V IF++ +  ++   + + GK
Sbjct: 135 MINQAFSLKVLHSYVDIFSKRAKCLISWFEEDFGK 169


>UniRef50_A6GGL1 Cluster: Cytochrome P450 family protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Cytochrome P450 family
           protein - Plesiocystis pacifica SIR-1
          Length = 454

 Score =  140 bits (339), Expect = 8e-32
 Identities = 77/249 (30%), Positives = 134/249 (53%), Gaps = 11/249 (4%)

Query: 256 RDDLDFNDENDVGEKKRLA-----FLDLMIESSQNGTNKISD-HEIKEEVDTIMFEGHDT 309
           RD LD   +  + E++R        LD+++ +    T +  D  ++++E+ T++  GH+T
Sbjct: 199 RDTLDAVIQGIIDERRRAGSGPGDLLDMLMAARDEDTGEGMDARQLRDELMTLVVAGHET 258

Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYP 369
           T+   S+   LL  H +   R+  E+ ++ GD  R  T  D  ++++ ERV+ ES+R+YP
Sbjct: 259 TSNALSWTWYLLSQHPEHVQRLRAEVDEVLGD--RLPTPEDLAKLEHTERVLKESMRVYP 316

Query: 370 PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQN 429
           PV  + R+ +  V +    Y +P GT + I  ++LHR P+++ DPE F+PD F PE +  
Sbjct: 317 PVWAVEREPSEAVEVG--GYRLPKGTMIGISPYVLHRDPQHWPDPERFDPDRFTPERSAG 374

Query: 430 RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAE 489
           R  Y+Y+PF AGPR C+G  +A            R F  +  +P +   ++  I L+   
Sbjct: 375 RPRYAYLPFGAGPRVCIGAGFALTEAKAILAMLVRRF-DLERVPGQAVHMEPGITLRPKH 433

Query: 490 GFQMKVEPR 498
           G +M++  R
Sbjct: 434 GLRMRLRVR 442



 Score = 51.2 bits (117), Expect = 6e-05
 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 2/115 (1%)

Query: 28  GNVIRVWLGSKLIVFLVDADDI-EIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86
           G+ +R   G    V L D +D+ ++++       K+  Y   K  LGEGL+ S G  W+ 
Sbjct: 32  GDHVRFRFGPFSYVSLRDLEDVRKVLVTDAQRYTKSKVYTALKLLLGEGLVTSEGAMWQR 91

Query: 87  HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTVDIL 140
            RK+ +P F    + SF       + ++ E+ +    G   DVHD M   T+ I+
Sbjct: 92  QRKLSSPAFRPRAVASFTEAMGACTRDLGERWRGLGDGAELDVHDEMMRLTLRIV 146


>UniRef50_Q17DZ0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 504

 Score =  140 bits (338), Expect = 1e-31
 Identities = 76/229 (33%), Positives = 122/229 (53%), Gaps = 4/229 (1%)

Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330
           K  AFL+ ++     G +  +D EI     T++  G++TTA   + V  +L +H D+Q R
Sbjct: 266 KSKAFLERLLTIQHKGRS-FTDDEIINHAYTMLVAGYETTALQLTNVCMMLAMHPDIQER 324

Query: 331 VYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYV 390
           V  E+  IF   D         ++ YL+  I E++RLYP VP+IAR+ N  + +   N  
Sbjct: 325 VASEIKTIFPSLDMEILPEALKDLPYLDMTINETMRLYPVVPLIARQSNSSLELDKVN-- 382

Query: 391 IPAGTTVVIGTFMLHRQPKYYKDPEV-FNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449
           IP GT  ++    LHR+   + +  + FNPDNFLPE  + RH Y++IP SAGPR C+G +
Sbjct: 383 IPTGTNFIVHIGALHRRKDVWGEEVLDFNPDNFLPEKVERRHPYAFIPLSAGPRVCIGNR 442

Query: 450 YAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           YA            + +R  +++  K+ K +  + LK    + +++E R
Sbjct: 443 YAMLSLKVFLIRLLQRYRLSTKLTRKDLKFKFQVTLKLKIPYTVQMERR 491



 Score = 64.1 bits (149), Expect = 8e-09
 Identities = 46/192 (23%), Positives = 96/192 (50%), Gaps = 7/192 (3%)

Query: 32  RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISS-GPKWRSHRKM 90
           ++WLG   ++ +   + ++ +LN    IDK   Y F +  LG+GL+    G +WR HRK 
Sbjct: 67  KIWLGPVPLINVQHPELVQKVLNEC--IDKPFAYDFME--LGQGLVSERYGQRWREHRKT 122

Query: 91  IAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILLETAMGISR 149
           ++P F+  IL SF+ IF + +++V+++L+    G+ FD+ +Y S  +  ++  T M  + 
Sbjct: 123 LSPLFNTKILHSFIPIFERATSDVMKRLEVVCDGRDFDLLEYTSSCSAKMVHGT-MVDTL 181

Query: 150 KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVI 209
              +E        +  + D + +R        + ++K++S ++ + +   I +   N  I
Sbjct: 182 SVSEEIIHSLITNLDIILDAVGKRILNGVYALKTLYKMSSVYRDEWRSRKICYETVNDGI 241

Query: 210 KNKKETYLENKA 221
              +   L  ++
Sbjct: 242 MKMRMNILNEQS 253


>UniRef50_A1BPR7 Cluster: CYP4AY1; n=2; Ips paraconfusus|Rep:
           CYP4AY1 - Ips paraconfusus
          Length = 491

 Score =  139 bits (337), Expect = 1e-31
 Identities = 78/229 (34%), Positives = 123/229 (53%), Gaps = 6/229 (2%)

Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327
           G KK++AFLD +++        +SD  I+ EVDT+MF GHDTTA   +F L LL  H +V
Sbjct: 261 GGKKKMAFLDHLLQYRDEQGKPLSDAFIRHEVDTVMFAGHDTTAVALAFALYLLAKHPEV 320

Query: 328 QARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387
           QA+   E  +I    ++  T  D   + YL+ V+ E+LRLYP VP  +R L  D+ +  +
Sbjct: 321 QAKARAEAREIVEGREK-LTIKDIQNLNYLDLVVKETLRLYPSVPFYSRALKEDM-VYQE 378

Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447
             ++P G  V+I  + ++R P  Y++P+ F P  FL +       +S + FSAGPR+C+G
Sbjct: 379 GKILPKGLVVLIVAYTVNRNPAVYQNPDQFIPTRFLDKEPVP---FSLLSFSAGPRNCIG 435

Query: 448 RKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQGDIILKRAEGFQMKV 495
           +K+A              F   I +    E  ++   +LK   G ++K+
Sbjct: 436 QKFALLELKVALSKLLLRFEFVIPDSDASEPVVEAVTVLKPKNGIRIKL 484



 Score =  108 bits (260), Expect = 3e-22
 Identities = 53/178 (29%), Positives = 99/178 (55%), Gaps = 2/178 (1%)

Query: 45  DADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFV 104
           D   ++  L S++ I K   Y   K WLG GLLIS G +WR+ RK++ P FH  IL+ F+
Sbjct: 78  DLSFLKWFLTSNIPIHKGDIYAVLKNWLGGGLLISGGEEWRNSRKILTPAFHFTILEQFI 137

Query: 105 GIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMA 162
            +F   +  + + L +EV      D++ Y++  T+D++ +T+MG+    Q +S  DY  A
Sbjct: 138 EVFEDATQVLGDVLSAEVTSKGVVDIYPYLTRYTLDVICQTSMGVKLNIQQQSHSDYINA 197

Query: 163 VMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENK 220
           V +M  II +R +      +  +  TS + ++ + + ++H ++N +I+ +++   + K
Sbjct: 198 VAEMGKIIVERAFNPLKVYDFTYIFTSDYWKEKQYVKLLHQVSNSIIEQRRQALEDQK 255


>UniRef50_Q9KFA6 Cluster: Cytochrome P450 hydroxylase; n=1; Bacillus
           halodurans|Rep: Cytochrome P450 hydroxylase - Bacillus
           halodurans
          Length = 453

 Score =  139 bits (336), Expect = 2e-31
 Identities = 74/225 (32%), Positives = 126/225 (56%), Gaps = 9/225 (4%)

Query: 276 LDLMIES-SQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           L ++I +  ++  + ++D ++++E+ T+   GH+TTA   S+   LL  H  V+ ++Y E
Sbjct: 236 LSMLISTYDEDDGSYMTDRQLRDEIITLFLAGHETTANTLSWAFYLLSQHPHVEEKLYQE 295

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           + Q+ G  +RPAT  D  ++ Y E VI E+LR+ P V +I+R+  +DVT+   +Y I AG
Sbjct: 296 VSQVLG--NRPATLEDMPKLSYAEHVIKETLRVQPTVWLISRRAEKDVTLG--DYHISAG 351

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNR-HYYSYIPFSAGPRSCVGRKYAXX 453
           + ++I  + +HR P+Y+ DP  F P+ +  +N  N+   Y Y PF  GPR C+G ++A  
Sbjct: 352 SEIMISQWGMHRNPRYFNDPLTFLPERW--DNNDNKPSKYVYFPFGGGPRVCIGERFALM 409

Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
                     R FR +  + E   K++  I L+   G  MK+  R
Sbjct: 410 EATLIMATIVREFR-MELVDELPIKMEPSITLRPKHGVTMKLRKR 453


>UniRef50_UPI0001555B83 Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily V, polypeptide 2, partial;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           cytochrome P450, family 4, subfamily V, polypeptide 2,
           partial - Ornithorhynchus anatinus
          Length = 412

 Score =  138 bits (335), Expect = 2e-31
 Identities = 66/184 (35%), Positives = 110/184 (59%), Gaps = 1/184 (0%)

Query: 32  RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMI 91
           ++W+G   +V L  A+ +E+IL+S   I K+  YRF +PWLG GLL S+G KWRS RKM+
Sbjct: 142 KLWIGPVPMVILYHAESVEVILSSSKQISKSYVYRFLEPWLGLGLLTSTGGKWRSRRKML 201

Query: 92  APTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGISRK 150
            PTFH +IL+ FVG+ N+++  +VEK +  V +  FD    ++   +DI+ ETAMG + +
Sbjct: 202 TPTFHFSILEEFVGVMNEHAQTLVEKFEKHVDRDAFDCFMDITLCALDIICETAMGRNIQ 261

Query: 151 TQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIK 210
            Q     +Y   + +M D+I +R    W+  +  + L    ++  + L ++H  T++VI 
Sbjct: 262 VQTNGDSEYVRTIYRMSDLIQRRILMPWLWLDPCYLLFQEGREHRQKLRVLHEFTDRVIA 321

Query: 211 NKKE 214
            + +
Sbjct: 322 ERSK 325



 Score = 81.0 bits (191), Expect = 7e-14
 Identities = 38/69 (55%), Positives = 51/69 (73%)

Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330
           +R AFLDL++E++ +  N +S  +++EEVDT MFEGHDTTAA  SFVL LLG   D Q +
Sbjct: 344 RRRAFLDLLLETADDARNGLSLRDVREEVDTFMFEGHDTTAAAMSFVLYLLGSCPDAQRK 403

Query: 331 VYDELYQIF 339
           V DEL ++F
Sbjct: 404 VNDELDRVF 412


>UniRef50_UPI0000D56468 Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 421

 Score =  138 bits (335), Expect = 2e-31
 Identities = 63/156 (40%), Positives = 103/156 (66%), Gaps = 2/156 (1%)

Query: 292 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADT 351
           D  +++E+  I+  G +++A   + VL +LGI+ +VQ ++  EL  IFGD +R  TF   
Sbjct: 266 DSPVEDEIQNILITGSESSALALALVLVVLGIYPEVQQKIALELDSIFGDDEREPTFEHI 325

Query: 352 LEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY 411
            +M+YLE VI E+LR+ P VP+I R   +D+ +  ++  IPAG+TV++    + ++ +++
Sbjct: 326 NQMEYLECVIKETLRILPIVPIIMRLAEQDIKL--EHCTIPAGSTVLVPIVHISKKSEFW 383

Query: 412 KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447
           K+P  FNPD FLP+N   RH  +++PFS GPR+CVG
Sbjct: 384 KEPNKFNPDRFLPKNNSERHRCTFLPFSYGPRNCVG 419



 Score = 79.0 bits (186), Expect = 3e-13
 Identities = 53/189 (28%), Positives = 92/189 (48%), Gaps = 15/189 (7%)

Query: 25  QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKW 84
           +T+  + + WLG  LIV     +D+EI+LNS    +K   Y++       GLLI+    W
Sbjct: 70  ETYPTLSKFWLGKDLIVITSRPEDVEIVLNSC--FEKPKFYKYAYKLFRTGLLIAPVNIW 127

Query: 85  RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETA 144
           +  R+MI PTF+   L++F  IF + +N +V  L+ E G+ FD+   +   T+D    TA
Sbjct: 128 KERRRMIGPTFNSKTLQTFTEIFGKQANRLVRVLEQECGREFDIFLKLFRCTLD----TA 183

Query: 145 MGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGL 204
            G     QD    +Y   +++  DI   R +  W++ +  +K +   ++  K        
Sbjct: 184 CG-----QD----NYLQKLIRAEDIATIRSFSPWLQVDFFWKKSPLGREMDKACAESFTF 234

Query: 205 TNKVIKNKK 213
             +++  KK
Sbjct: 235 IKQILSLKK 243


>UniRef50_Q3IR83 Cluster: Unspecific monooxygenase; n=1;
           Natronomonas pharaonis DSM 2160|Rep: Unspecific
           monooxygenase - Natronomonas pharaonis (strain DSM 2160
           / ATCC 35678)
          Length = 448

 Score =  138 bits (334), Expect = 3e-31
 Identities = 83/275 (30%), Positives = 137/275 (49%), Gaps = 14/275 (5%)

Query: 224 IIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESS 283
           ++P  +   T    E  A   + LS+ + +  R+ L   +  D  +      L ++I + 
Sbjct: 183 VLPDWVPTPTSGEFEQAAAGIRELSEQLIERRRESLAAGERPDASD-----MLTMLIRAE 237

Query: 284 QNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD 343
            N      +++I++EV T +  GH+TTA   ++ LCLL  H + + RV  E  +  GD  
Sbjct: 238 DNPDIDYPENQIRDEVATFLIAGHETTALSLTYTLCLLSWHPEARRRVRQEADEALGDG- 296

Query: 344 RPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFM 403
            P T  D  E+ Y  RV  E+LRLYPP   + R+ N DVT+    Y IP G+ V++  + 
Sbjct: 297 -PPTHDDLAELTYTRRVYDEALRLYPPAWGVFRQANGDVTLG--QYTIPDGSAVIMPLWS 353

Query: 404 LHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXX 463
           +HR   Y++ P+ F+PD +  E    R   +Y PFS+GP +C+GR +A            
Sbjct: 354 IHRDGSYFEQPDTFDPDRW--ERRTPRAVDAYRPFSSGPHACIGRGFALAGSTLVLARLV 411

Query: 464 RNFRTISEIPEKEF-KLQGDIILKRAEGFQMKVEP 497
           R+F    ++PE     L+    L+ A+G +  ++P
Sbjct: 412 RDFDI--DVPESALDDLRLTPTLRPADGVEATIQP 444



 Score = 34.3 bits (75), Expect = 7.7
 Identities = 21/89 (23%), Positives = 38/89 (42%)

Query: 75  GLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSG 134
           GL+ S G  W   R ++AP+F    + ++     +      ++  +   +T D+H  M+ 
Sbjct: 83  GLVQSEGALWSQQRSVMAPSFSGEQVTAYANTTGRRIEARADQWAAAGARTTDLHREMTS 142

Query: 135 TTVDILLETAMGISRKTQDESGFDYAMAV 163
            TV +  E  +G    T+    F   M V
Sbjct: 143 LTVRVASEILLGEDIGTERADQFHEWMQV 171


>UniRef50_Q82D73 Cluster: Putative cytochrome P450; n=2;
           Streptomyces avermitilis|Rep: Putative cytochrome P450 -
           Streptomyces avermitilis
          Length = 470

 Score =  136 bits (329), Expect = 1e-30
 Identities = 77/241 (31%), Positives = 116/241 (48%), Gaps = 4/241 (1%)

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
           +E D GE+     + L++ +       +   E++E+V   +  GH+TTA   +F L LL 
Sbjct: 230 NEGDGGEESGEDLVTLLVRAGNAEDGSLDAAELREQVLIFLLAGHETTATALAFALHLLA 289

Query: 323 IHQDVQARVYDELYQIFGD-SDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381
            H + Q RV DE  ++ G    R  T AD   + YL  V+ E++RLYP  PVI R+   D
Sbjct: 290 RHPEQQRRVRDEADRVLGGPGGRAPTAADMEALPYLTMVLKEAMRLYPSAPVIGRRAVAD 349

Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441
             +      IPAG  + +  ++ HR P Y+ DPE F+P+ F PE    R  Y++ PF  G
Sbjct: 350 AEVDGVR--IPAGADLFVSPWVTHRHPDYWPDPERFDPERFTPEAEAGRPRYAWFPFGGG 407

Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRV 501
           PR+C+G+  +            R F     + E+E  L   I L      + +V PR   
Sbjct: 408 PRACIGQHLSMLESVLGLAVLIREFE-FEAVGEEEVPLGAGITLLAKGPARCRVIPRSSG 466

Query: 502 P 502
           P
Sbjct: 467 P 467


>UniRef50_UPI0000D55FA3 Cluster: PREDICTED: similar to Cytochrome
           P450 4g15 (CYPIVG15); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4g15 (CYPIVG15) -
           Tribolium castaneum
          Length = 193

 Score =  136 bits (328), Expect = 2e-30
 Identities = 68/169 (40%), Positives = 96/169 (56%), Gaps = 2/169 (1%)

Query: 302 IMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVI 361
           ++F G  + A    +VL +L IH ++Q ++Y+EL  IFG+SDR   F D  ++ YL+RVI
Sbjct: 1   MVFTGSGSLAITECYVLLMLAIHPEIQEKIYEELLTIFGNSDRDLCFKDLSKLCYLDRVI 60

Query: 362 LESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDN 421
            E+LRL+P  P IAR L+ D  I  + YVIP GT  +I    L R    + +P  F+PD 
Sbjct: 61  KETLRLFPIAPYIARLLDSD--IHMEKYVIPKGTFALIPITYLQRNSNLWSEPLRFDPDR 118

Query: 422 FLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTIS 470
           FLPE    R    Y+PFS G R+C+G KYA            R ++ +S
Sbjct: 119 FLPEQVATRERCVYLPFSYGSRNCIGLKYAEISLKATLATILRKYKYVS 167


>UniRef50_Q6SPQ5 Cluster: CYP342A1; n=1; Nereis virens|Rep: CYP342A1
           - Nereis virens (Sandworm)
          Length = 508

 Score =  136 bits (328), Expect = 2e-30
 Identities = 67/168 (39%), Positives = 106/168 (63%), Gaps = 5/168 (2%)

Query: 287 TNKIS-DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDR 344
           T K+  D EI++EVDT MFEGHDTTA+G S++L  L  H +VQ +   E+ ++ G  SD 
Sbjct: 322 TEKVCLDREIRDEVDTFMFEGHDTTASGISWILYELSGHPEVQEQAGQEVIRVIGSQSDG 381

Query: 345 PATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFML 404
              ++D   + YL + I E++R++PPVP I R+L++D+ I+     IP  T   +  + +
Sbjct: 382 TIEWSDLSRLPYLSQCIKEAMRVHPPVPFIGRQLSQDIIIN--GCTIPKDTICEVSIYGV 439

Query: 405 HRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           H  P+ + KD   F P+ F P+N +++  + YIPFSAG R+C+G+ +A
Sbjct: 440 HHNPEVWGKDHMEFKPERFHPDNMKDKDAFDYIPFSAGSRNCIGQNFA 487



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 1/46 (2%)

Query: 52  ILNSHVHIDKATEYRFF-KPWLGEGLLISSGPKWRSHRKMIAPTFH 96
           ++ + VH+ +        K WLG+GLL+SSG KW  +R+++ P FH
Sbjct: 127 VIRTKVHLHRIWPVMLLLKEWLGDGLLLSSGSKWFRNRRLLTPAFH 172


>UniRef50_Q4U3Y5 Cluster: CYP325D1; n=1; Anopheles gambiae|Rep:
           CYP325D1 - Anopheles gambiae (African malaria mosquito)
          Length = 304

 Score =  134 bits (323), Expect = 7e-30
 Identities = 69/179 (38%), Positives = 107/179 (59%), Gaps = 5/179 (2%)

Query: 274 AFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYD 333
           A LD ++  +++G   +SD EI + + +I+  G+DTTA         L +H  VQ ++Y 
Sbjct: 125 AMLDRLLSVNEDGP--LSDTEIVQNIYSIVGAGNDTTAHSLGHTCLFLAMHPAVQRKLYQ 182

Query: 334 ELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPA 393
           EL  +F  +D P T     ++ Y+E VI ESLRL PP   +AR+   D+T+  +  +IP 
Sbjct: 183 ELRDVFYSADEPITEEKLKQLSYMECVIKESLRLAPPGATVAREAQEDLTV--EGQLIPR 240

Query: 394 GTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           GTTVV+  F LHR+  ++  D E F+PD FL E  +NR   +++PF+ G R+C+G +YA
Sbjct: 241 GTTVVVSLFALHRRKDFWGADAERFDPDRFLSERCKNRMGCAFMPFNTGSRNCIGSRYA 299


>UniRef50_Q4STK8 Cluster: Chromosome undetermined SCAF14158, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14158, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 612

 Score =  133 bits (322), Expect = 9e-30
 Identities = 100/389 (25%), Positives = 181/389 (46%), Gaps = 18/389 (4%)

Query: 76  LLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYM 132
           LL+S+G  W   R+++ P FH +ILK++V  FN ++N + +K   L +E     +  + +
Sbjct: 174 LLLSNGEVWLRKRRLLTPAFHFDILKNYVAKFNTSTNTMHDKWRRLAAEGPTHVEAFEDV 233

Query: 133 SGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFK 192
           +  T+D LL+ A       Q  S  +YA A++++ D+I +R  +     + ++  T   K
Sbjct: 234 TLMTLDSLLKCAFSYDSDCQQSSS-EYASAIVQLSDLIIERRQRILHHWDWIYWRTRQGK 292

Query: 193 QQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVF 252
           +  + L I+H  T  V++ ++ T +  K + +     ++F          + K L+D   
Sbjct: 293 RFQQALSIVHKFTRDVVQERR-TLIGQKGE-MAAQGKKDFVDIILLSKDEDGKGLTDEEI 350

Query: 253 KGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTN---KISDHEIKEEVDTIMFEGHDT 309
           +   +   F  E  +  K  L  +   + S     N   ++     +  +      GHDT
Sbjct: 351 QAEANTFMFAGEQWLMLK--LVDVSSNLTSGTRSVNLVLRLGSSCSQMSLSACSPTGHDT 408

Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD-RPATFADTLEMKYLERVILESLRLY 368
           TA+   + L  L  H   Q +   E+  +    D     + D   + +    I ESLRL+
Sbjct: 409 TASAICWSLYNLARHDHYQEKCRKEVMDLMEGRDVHEINWEDLSSLPFTTMCIRESLRLH 468

Query: 369 PPVPVIARKLNRDVTIS---TKNYVI---PAGTTVVIGTFMLHRQPKYYKDPEVFNPDNF 422
            PV  + R+  +DV +    TKN  I   P G   ++  +  H  P  + +P  F+P  F
Sbjct: 469 SPVQAVTRRYLQDVELPGGHTKNETIACYPEGAICLVSIYGTHHNPAVWTNPHDFDPLRF 528

Query: 423 LPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
            P N +    +++IPFS+GPR+C+G+K+A
Sbjct: 529 DPTNQKGLSSHAFIPFSSGPRNCIGQKFA 557


>UniRef50_A7SJV6 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 512

 Score =  133 bits (322), Expect = 9e-30
 Identities = 72/213 (33%), Positives = 113/213 (53%), Gaps = 5/213 (2%)

Query: 288 NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPAT 347
           NK+SD EI  +  T +  G++TT+   +F   LL ++ D Q R+ +E+ ++         
Sbjct: 303 NKLSDDEIVAQCFTFILAGYETTSNTMAFTSYLLALNPDKQDRLIEEIDEVAATVGDNFD 362

Query: 348 FADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ 407
           +   L M+YLE V+ E+LRLYPP     R  N+  TI+ + +  P G  V+I  F +HR 
Sbjct: 363 YDTVLGMEYLEMVVQEALRLYPPGFRFGRTCNQSCTINGQFF--PKGCIVLIPVFAMHRD 420

Query: 408 PKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467
           P+ + +PE F P+ F  E  Q RH Y+++PF  GPR+C+G ++A            R +R
Sbjct: 421 PEIWPEPEKFQPERFTAEAKQARHPYAHLPFGGGPRNCIGMRFALLEAKMALVYILRYYR 480

Query: 468 TISEIPEKE--FKLQGDIILKRAEGFQMKVEPR 498
            +   PE E   +LQG I +    G  +K+  R
Sbjct: 481 -LERCPETEVPVQLQGTITISPKHGIYLKITKR 512



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 4/132 (3%)

Query: 25  QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVH--IDKATEYRFFKPWLGEGLLISSGP 82
           +T+G +   ++G++  + + D +  + IL       +++        P   + LL     
Sbjct: 75  KTYGRLCGYYMGTRAAILVADPEMAKQILVKEFDKFVNRPIVQSAQTPPTDKTLLSLQDD 134

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDIL 140
            WR  R  I PTF    LK  + + N++   +VEKL    + GK+ DV       T++ +
Sbjct: 135 DWRRLRHTITPTFSAVKLKQVLPLINESCRILVEKLGEACKDGKSVDVLRSYGKFTMETI 194

Query: 141 LETAMGISRKTQ 152
           + TA GI  +TQ
Sbjct: 195 VTTAFGIDCQTQ 206


>UniRef50_Q98T91 Cluster: Cytochrome P450 3A40; n=16;
           Euteleostomi|Rep: Cytochrome P450 3A40 - Oryzias latipes
           (Medaka fish) (Japanese ricefish)
          Length = 502

 Score =  133 bits (321), Expect = 1e-29
 Identities = 79/245 (32%), Positives = 128/245 (52%), Gaps = 14/245 (5%)

Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKI-----SDHEIKEEVDTIMFEGHDTTAAGSSF 316
           N EN+  +K R+ FL LMI+S +N  N +     SDHEI  +    +F G++TT++  +F
Sbjct: 259 NHENNK-QKSRIDFLQLMIDSQKNNQNGLQDKGLSDHEILSQAMIFIFAGYETTSSSLTF 317

Query: 317 VLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIAR 376
           +   L  + +V  ++  E+   F +   P  +   +EM+YL+ V+ ESLRLYP    IA 
Sbjct: 318 LAYNLATNPEVMKKLQKEIDATFPNK-APVQYVPLMEMEYLDCVVNESLRLYP----IAA 372

Query: 377 KLNR--DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434
           +L R    T+     VIP    V++ T+ LHR P+ + +PE F P+ F  EN      Y+
Sbjct: 373 RLERVAKATVEVNGLVIPKDMVVMVPTWPLHRDPELWPEPEKFKPERFSKENKDTFDPYT 432

Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQGDIILKRAEGFQM 493
           Y+PF AGPR+C+G ++A            + +  ++ +  E  F++     L      Q+
Sbjct: 433 YMPFGAGPRNCIGMRFALVMMKLAVVEILQTYDFSVCKETEVPFEMDVQGFLAPKRPIQL 492

Query: 494 KVEPR 498
           K+ PR
Sbjct: 493 KLTPR 497



 Score = 43.6 bits (98), Expect = 0.013
 Identities = 27/144 (18%), Positives = 65/144 (45%), Gaps = 5/144 (3%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVH--IDKATEYRFFKPWLGEGLLISSGPKW 84
           +G    ++ G + ++ + D   I+ +L    +        +R   P L + + I+   +W
Sbjct: 68  YGKTWGIYDGRQPVLCITDPATIKAVLVKECYSLFTNRRNFRLNGP-LYDAVSIAEDDQW 126

Query: 85  RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLE 142
           +  R +++P+F    LK    I   +S N+++ +K +V K    ++ +Y    ++D++  
Sbjct: 127 KRIRSVLSPSFTSGRLKEMFDIMKHHSANLIQSMKKKVDKDEPLEMKEYFGPYSMDVVTS 186

Query: 143 TAMGISRKTQDESGFDYAMAVMKM 166
           TA  +   + +     +   + KM
Sbjct: 187 TAFSVDIDSLNNPSDPFVTNIKKM 210


>UniRef50_Q6PH32 Cluster: Cytochrome P450, family 4; n=7;
           Clupeocephala|Rep: Cytochrome P450, family 4 - Danio
           rerio (Zebrafish) (Brachydanio rerio)
          Length = 458

 Score =  132 bits (320), Expect = 2e-29
 Identities = 69/194 (35%), Positives = 110/194 (56%), Gaps = 3/194 (1%)

Query: 251 VFKGYRDDLDFNDENDVGEKKR-LAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDT 309
           V +  ++ L   +E  + + +R L FLD+++ +       +SD +I+ EVDT MFEGHDT
Sbjct: 261 VIRKRKEVLKMEEEQGIVKNRRYLDFLDILLSARDEHQQGLSDEDIRAEVDTFMFEGHDT 320

Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYP 369
           TA+G S++   L  + + Q +   E+ Q     D    + D  ++ Y    I ESLRL+P
Sbjct: 321 TASGISWIFYNLACNPEHQEKCRQEIQQALDGKD-TLEWEDLNKIPYTTMCIKESLRLHP 379

Query: 370 PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQN 429
           PVP I+RKL + +T       +P G T+ +  + +H     +++P  F+P  FLPEN  N
Sbjct: 380 PVPGISRKLTKPLTF-FDGRTVPEGCTIGVSIYGIHMNSTVWENPYKFDPLRFLPENAAN 438

Query: 430 RHYYSYIPFSAGPR 443
           R  ++++PFSAGPR
Sbjct: 439 RSPHAFVPFSAGPR 452



 Score =  105 bits (253), Expect = 2e-21
 Identities = 55/196 (28%), Positives = 104/196 (53%), Gaps = 3/196 (1%)

Query: 33  VWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIA 92
           +W G  L V  +        + +         Y+FF PWLG+GLL+S+G KW  HR+++ 
Sbjct: 83  LWFGPSLAVLNIHHPSYAKTILTTTEPKDDYAYKFFIPWLGDGLLVSTGQKWFRHRRLLT 142

Query: 93  PTFHINILKSFVGIFNQNSNNVVEK--LKSEVGKTFDVHDYMSGTTVDILLETAMGISRK 150
           P FH ++LK +V + + ++  +++K  + S   ++F++  ++S  T+D +++ A   +  
Sbjct: 143 PGFHYDVLKPYVKLISDSTKVMLDKWEVHSRSEESFELFKHVSLMTLDSIMKCAFSCNSN 202

Query: 151 TQDESGFD-YAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVI 209
            Q +SG + Y  AV  +C +++ R   F   S+ +F L+    +  K   I H  T +VI
Sbjct: 203 CQTDSGTNPYIQAVFDLCHLVNLRFRVFPYHSKAIFHLSPHGYRFRKAASIAHNHTAEVI 262

Query: 210 KNKKETYLENKAKGII 225
           + +KE     + +GI+
Sbjct: 263 RKRKEVLKMEEEQGIV 278


>UniRef50_Q3L917 Cluster: Cytochrome P450; n=1; Rhodococcus
           erythropolis PR4|Rep: Cytochrome P450 - Rhodococcus
           erythropolis (strain PR4)
          Length = 510

 Score =  132 bits (320), Expect = 2e-29
 Identities = 77/224 (34%), Positives = 120/224 (53%), Gaps = 6/224 (2%)

Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           LDLM+ S+   T  K+    I+ +V T +  G++TTA   +F L  L  H DV      E
Sbjct: 292 LDLMLHSADAETGEKLDPVNIRNQVFTFLVAGNETTAGTLAFALYFLSRHPDVADTARAE 351

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           +  +    + PA F D   M+YL RV+ E+LRL+P  P   RK+  D T+  + Y +P G
Sbjct: 352 VADVTA-GETPA-FEDVARMRYLRRVVDETLRLWPSAPGYFRKVRTDTTLGGR-YDMPKG 408

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454
           + V +    LHR P + +DPE F+PD F PEN + R  ++Y PF  GPR+C+GR++A   
Sbjct: 409 SWVFVLLPQLHRDPVWGEDPESFDPDRFKPENVKKRPAHAYRPFGTGPRACIGRQFALHE 468

Query: 455 XXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
                    + +   S+ PE +  ++  + LK   GF++ ++ R
Sbjct: 469 AVLALAIILQRYNFQSD-PEYKLDIRETLSLKPV-GFELSLQRR 510


>UniRef50_P05184 Cluster: Cytochrome P450 3A3; n=159;
           Euteleostomi|Rep: Cytochrome P450 3A3 - Homo sapiens
           (Human)
          Length = 504

 Score =  132 bits (318), Expect = 3e-29
 Identities = 77/237 (32%), Positives = 128/237 (54%), Gaps = 11/237 (4%)

Query: 269 EKKRLAFLDLMIESSQNGTNK-----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323
           +K R+ FL LMI+S +N         +SD E+  +    +F G++TT++  SF++  L  
Sbjct: 265 QKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELAT 324

Query: 324 HQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383
           H DVQ ++ +E+  +  +   P T+   L+M+YL+ V+ E+LRL+P    + R   +DV 
Sbjct: 325 HPDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVE 383

Query: 384 ISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443
           I+     IP G  V+I ++ LHR PKY+ +PE F P+ F  +N  N   Y Y PF +GPR
Sbjct: 384 IN--GMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 441

Query: 444 SCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDI--ILKRAEGFQMKVEPR 498
           +C+G ++A            +NF +     E +  L+  +  +L+  +   +KVE R
Sbjct: 442 NCIGMRFALMNMKLALIRVLQNF-SFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 497



 Score = 44.8 bits (101), Expect = 0.005
 Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 5/126 (3%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKP--WLGEGLLISSGPKW 84
           +G V   + G + ++ + D D I+++L    +    T    F P  ++   + I+   +W
Sbjct: 68  YGKVWGFYDGQQPVLAITDPDMIKLVLVKECY-SVFTNREPFGPVGFMKSAISIAEDEEW 126

Query: 85  RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLE 142
           +  R +++PTF    LK  V I  Q  + +V  L+   E GK   + D     ++D++  
Sbjct: 127 KRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITS 186

Query: 143 TAMGIS 148
           ++ G++
Sbjct: 187 SSFGVN 192


>UniRef50_A7D7T8 Cluster: Cytochrome P450; n=1; Halorubrum
           lacusprofundi ATCC 49239|Rep: Cytochrome P450 -
           Halorubrum lacusprofundi ATCC 49239
          Length = 469

 Score =  131 bits (316), Expect = 5e-29
 Identities = 63/176 (35%), Positives = 101/176 (57%), Gaps = 6/176 (3%)

Query: 276 LDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDEL 335
           L +++ +   G    +D  +++E+ T++  GHDTTA   ++   LL  H + + RV  E 
Sbjct: 255 LSVLLRARDRGEQ--TDENLRDELVTMLLAGHDTTALALTYTFYLLSNHPEARERVAREA 312

Query: 336 YQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGT 395
                 +D P T AD  EMK+ ERV+ ESLRLYPPV  + R+   DV +    Y IP G+
Sbjct: 313 AA--ATADGPPTAADAREMKFTERVLNESLRLYPPVYTLFREPKLDVKLG--GYRIPEGS 368

Query: 396 TVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
            +++  + +HR P++Y DPE F+P  + PE    R  +++ PF  GPR C+G+ ++
Sbjct: 369 ALMLSQWAIHRSPRWYDDPETFDPSRWEPERQSKRPRFAFFPFGGGPRHCIGKAFS 424



 Score = 48.4 bits (110), Expect = 4e-04
 Identities = 30/125 (24%), Positives = 59/125 (47%), Gaps = 4/125 (3%)

Query: 24  AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYR--FFKPWLGEGLLISSG 81
           A ++G+V+R  LG +    L +  D+E +L +     +  ++        LG GLL+S G
Sbjct: 32  ADSYGDVVRFDLGPRETYMLTNPADVERVLVADAERYRKPDFGDDAIDTLLGNGLLMSEG 91

Query: 82  PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILL 141
             W   R++ +P+FH   + +  G   +++ + +       G+  DV   ++  TV I++
Sbjct: 92  ETWERQRRLASPSFHSRRIGALAGTMVEHTESQLADWAD--GEVVDVQLEVARLTVKIIV 149

Query: 142 ETAMG 146
               G
Sbjct: 150 SAMFG 154


>UniRef50_Q8WQN9 Cluster: Cytochrome P450 CYP4J5; n=22;
           Endopterygota|Rep: Cytochrome P450 CYP4J5 - Anopheles
           gambiae (African malaria mosquito)
          Length = 153

 Score =  130 bits (315), Expect = 6e-29
 Identities = 66/154 (42%), Positives = 90/154 (58%), Gaps = 4/154 (2%)

Query: 298 EVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA---DTLEM 354
           EVDT MFEGHDTT +   F+L  L    ++Q R++ EL Q+   +D         D    
Sbjct: 1   EVDTFMFEGHDTTGSALVFILLTLSWELEIQTRLHQELSQLATQNDLTDGHLSPNDLNSA 60

Query: 355 KYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDP 414
           K+ +RVI E LRL+PPV  I+R +  ++ +     +IP G    +  F LHR P  + DP
Sbjct: 61  KFFDRVIKECLRLWPPVAFISRSVTEEIHLPDGR-IIPQGCIANLHIFDLHRDPAQFPDP 119

Query: 415 EVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
           E F+PD FLPE    R  Y+YIPFSAGPR+C+G+
Sbjct: 120 ERFDPDRFLPECVSQRSPYAYIPFSAGPRNCIGQ 153


>UniRef50_Q095M8 Cluster: Cytochrome P450 4A5; n=1; Stigmatella
           aurantiaca DW4/3-1|Rep: Cytochrome P450 4A5 -
           Stigmatella aurantiaca DW4/3-1
          Length = 374

 Score =  130 bits (314), Expect = 8e-29
 Identities = 71/230 (30%), Positives = 117/230 (50%), Gaps = 5/230 (2%)

Query: 269 EKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQ 328
           ++K L  + +     + G   +SD +++ E+  +   GHDTTA G +F   LL  H +  
Sbjct: 150 DRKDLLAMYMSAVDEETGEG-MSDEQLRHELMNLFLAGHDTTANGLAFTFYLLSKHPEAL 208

Query: 329 ARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
            RV +E   + G+  R  T  D  ++ Y      E+LR+YPP   ++R   R+  +   +
Sbjct: 209 KRVDEERDAVLGNG-RMVTNEDLPQLNYARWSFEEALRIYPPTFAMSRTSVRE--LKHND 265

Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
           YVIPAG+ + +  + LHR P+ + +P+ F P+ F PE ++ RH ++Y+PF AGPR C+G 
Sbjct: 266 YVIPAGSNIFVCQWALHRNPRLWPNPDHFEPERFSPERSEGRHRFAYLPFGAGPRICIGA 325

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
             A            + FR  SE P  E +L   + +    G  M++  R
Sbjct: 326 HLARTEAQMIIAMLLQRFRLNSE-PGYEPRLVARLFVTAEPGISMRLSRR 374



 Score = 42.3 bits (95), Expect = 0.029
 Identities = 22/72 (30%), Positives = 35/72 (48%)

Query: 70  PWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVH 129
           P +G GL   SG  W+  R+M  P F    + +F GI  +     + + ++  G+T DV 
Sbjct: 6   PAIGAGLSTLSGDPWKRQRRMANPAFSRASIATFEGIMQKAIAEAIVEWEARAGETIDVT 65

Query: 130 DYMSGTTVDILL 141
             M   T+ I+L
Sbjct: 66  GEMKRLTLRIVL 77


>UniRef50_A7DM29 Cluster: Cytochrome P450; n=2; Methylobacterium
           extorquens PA1|Rep: Cytochrome P450 - Methylobacterium
           extorquens PA1
          Length = 471

 Score =  130 bits (313), Expect = 1e-28
 Identities = 77/227 (33%), Positives = 123/227 (54%), Gaps = 14/227 (6%)

Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           L L++++    T  ++SD  + + + T +  GH+TTA    + L +L  H  V+AR+ DE
Sbjct: 252 LGLLLQAKDPETGERLSDESLIDNLLTFVAAGHETTALALIWTLRVLADHPAVEARILDE 311

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           +  +  D   PA  A    + +  +V+LE +RLYPP P+I R+   +V +   + VIPAG
Sbjct: 312 IAGLGAD---PAPEALD-RLAFTRQVVLEVMRLYPPAPLIVRRTAEEVRLG--DMVIPAG 365

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454
            +V +  + LHR    ++ P+VF+PD F PE T +R  Y+Y+PF AGPR C+G   A   
Sbjct: 366 ESVHVPVYALHRHQSLWERPDVFDPDRFAPELTASRDRYAYLPFGAGPRVCIGMGLALTE 425

Query: 455 XXXXXXXXXRNFRTI---SEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
                      FR +   +E+P  +F+    + L+   G +MKV PR
Sbjct: 426 CLVILATLLPAFRFVPAKAEMPATQFR----VTLRPKGGMKMKVVPR 468



 Score = 39.5 bits (88), Expect = 0.20
 Identities = 16/39 (41%), Positives = 23/39 (58%)

Query: 66  RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFV 104
           R   P LG G+L + GP WR  R+  AP F  + +K+F+
Sbjct: 89  RALAPALGSGILTADGPHWRGQRRTAAPMFRPDRVKAFI 127


>UniRef50_Q3I414 Cluster: Cytochrome P450; n=18; Cucujiformia|Rep:
           Cytochrome P450 - Leptinotarsa decemlineata (Colorado
           potato beetle)
          Length = 510

 Score =  129 bits (312), Expect = 1e-28
 Identities = 67/211 (31%), Positives = 109/211 (51%), Gaps = 2/211 (0%)

Query: 281 ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG 340
           E + +GT+   D EI  +       G +T++   +F L  L  H ++Q +V  E+  +  
Sbjct: 290 EHTGDGTSLTMD-EIVAQSFVFFIAGFETSSTTMTFALYQLATHPEIQEKVRSEINSVLE 348

Query: 341 DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIG 400
             +   T+    E+KY+ +VI E+LR+YP +PV+ R+   D  I   + +I  G  V I 
Sbjct: 349 KHNNQITYDALNELKYMGKVIDETLRMYPALPVVTRRCVEDYRIPDSDVIIEKGIEVFIP 408

Query: 401 TFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXX 460
              +H  P+YY++PEVF+P+ F  EN Q RH Y++IPF  GPR C+G ++          
Sbjct: 409 IKAIHYDPEYYENPEVFDPERFNEENIQGRHPYAHIPFGEGPRICIGLRFGVMQSKVGLV 468

Query: 461 XXXRNFR-TISEIPEKEFKLQGDIILKRAEG 490
              +NFR T+S   +   K+  +  +   EG
Sbjct: 469 SILKNFRVTLSSKTKLPLKIDVNSFIPTTEG 499


>UniRef50_Q177R7 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 496

 Score =  128 bits (308), Expect = 5e-28
 Identities = 73/241 (30%), Positives = 128/241 (53%), Gaps = 7/241 (2%)

Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVD---TIMFEGHDTTAAGSSFVL 318
           NDE D  + K   F    I  +Q  TN I   E +E +D   TI+  G DT+A   +F  
Sbjct: 258 NDETD--DDKTEGFRKPQIFVNQIFTNTIRKFERQEIIDNIITIVGAGTDTSATAIAFTF 315

Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKL 378
             L ++Q+ Q +VY+E+ ++F +S+   T     +++Y + V+ E LRLYP  P++ R+ 
Sbjct: 316 LQLAMYQEHQQKVYEEIVKVFPESEPHITTEALKKLQYTKMVLNECLRLYPVAPILLREN 375

Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIP 437
             D+T+      +P G  + I  + +HR+   +  D + F P+ F PE +  RH ++++ 
Sbjct: 376 TADITL-CGGVRVPKGNILTIDVYNIHRRKDVWGPDADEFIPERFSPERSAGRHPFAFLT 434

Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
           FS G R+C+G +YA            +NFR  ++I E++ + + D +L+   G  +++E 
Sbjct: 435 FSGGSRNCIGSRYAMISMKIMMVYLLKNFRFKTKIREEDIRYKFDALLRIEGGHLVQIEK 494

Query: 498 R 498
           R
Sbjct: 495 R 495



 Score = 68.5 bits (160), Expect = 4e-10
 Identities = 42/170 (24%), Positives = 89/170 (52%), Gaps = 6/170 (3%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           + R++LG ++++   D    + I+     ++K   Y+FF   L EG+  +    W+  RK
Sbjct: 68  LFRLYLGPRMLLCTSDPTVAQAIMTDANCMEKPYVYKFFN--LNEGVFAAKTHIWKGQRK 125

Query: 90  MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGI 147
            + P F+  IL+SFV IF + S  ++++L + VGK  T ++ ++ S  T++++  T +G 
Sbjct: 126 ALNPAFNSKILESFVSIFCEVSKTMIQRLDT-VGKGDTINIMEHASRCTLEMVCSTTLGF 184

Query: 148 SRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKL 197
           +    D+   +    + +   I  +R  KF++  + +++ T  +K +  L
Sbjct: 185 NVDIFDQID-EMGHKIEQFFYIAARRILKFYLHVDSIYRWTKDYKDEQTL 233


>UniRef50_Q495Y1 Cluster: CYP3A43 protein; n=4; Homo sapiens|Rep:
           CYP3A43 protein - Homo sapiens (Human)
          Length = 393

 Score =  128 bits (308), Expect = 5e-28
 Identities = 66/202 (32%), Positives = 109/202 (53%), Gaps = 7/202 (3%)

Query: 269 EKKRLAFLDLMIESSQNGTNK----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324
           +K R+ F   MI+S  +   K    +SD E+  +   I+F  +DTT+    F++  L  H
Sbjct: 155 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 214

Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI 384
            DVQ ++ +E+  +  +   P T+   ++M+YL+ V+ E+LRL+P V  + R   +D+ I
Sbjct: 215 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 273

Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRS 444
           +     IP G  V++  + LH  PKY+ +PE F P+ F  +N  +   Y YIPF AGPR+
Sbjct: 274 N--GVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 331

Query: 445 CVGRKYAXXXXXXXXXXXXRNF 466
           C+G ++A            +NF
Sbjct: 332 CIGMRFALTNIKLAVIRALQNF 353


>UniRef50_Q8WQN1 Cluster: Cytochrome P450 CYP4H24; n=23;
           Culicidae|Rep: Cytochrome P450 CYP4H24 - Anopheles
           gambiae (African malaria mosquito)
          Length = 193

 Score =  127 bits (307), Expect = 6e-28
 Identities = 67/191 (35%), Positives = 100/191 (52%), Gaps = 4/191 (2%)

Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDR--PATFADTLEMKYLERVILESLRL 367
           T +G SF    L  H ++Q ++Y E+  + G   R  P T+       YL+ V+ ESLRL
Sbjct: 4   TTSGISFTFYQLAKHPEIQEKLYREIQDVLGGEYRHVPLTYNTLQNFPYLDMVVKESLRL 63

Query: 368 YPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENT 427
            PPV  I R+L  D+ ++     IPAGT   I  +++HR P  Y DPE F+P+ F   NT
Sbjct: 64  LPPVSFIGRRLADDIEMN--GVTIPAGTDFTIPIYVIHRNPVVYPDPERFDPERFSDGNT 121

Query: 428 QNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKR 487
           Q R  Y YIPFS G R+C+G++YA              +R +      E +L+ D++L+ 
Sbjct: 122 QRRGPYDYIPFSIGSRNCIGQRYALLEMKVAIVRMVSFYRILPGDTMHEIRLKTDLVLRP 181

Query: 488 AEGFQMKVEPR 498
            +   +K+  R
Sbjct: 182 DKSIPIKLVAR 192


>UniRef50_Q8T632 Cluster: Cytochrome P450 CYP6P3; n=42; Diptera|Rep:
           Cytochrome P450 CYP6P3 - Anopheles gambiae (African
           malaria mosquito)
          Length = 509

 Score =  127 bits (307), Expect = 6e-28
 Identities = 71/225 (31%), Positives = 113/225 (50%), Gaps = 16/225 (7%)

Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISD-------------HEIKEEVDTI 302
           ++ +D+ + N+V   KR  F++LM++    G    SD             +E+  +    
Sbjct: 255 KETVDYREANNV---KRNDFMNLMLQIKNKGKLDDSDDGSLGKGEVGMTQNELAAQAFVF 311

Query: 303 MFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVIL 362
              G +T++   SF L  L  + D+Q R+ +E+ +   ++    T+   + +KYL+ VI 
Sbjct: 312 FLAGFETSSTTQSFCLYELAKNPDIQERLREEINRAIAENGGEVTYDVVMNIKYLDNVID 371

Query: 363 ESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNF 422
           E+LR YPPV  + R  + D  I    +VIP  T V I  + + R P +Y DPE FNPD F
Sbjct: 372 ETLRKYPPVESLTRVPSVDYLIPGTKHVIPKRTLVQIPAYAIQRDPDHYPDPERFNPDRF 431

Query: 423 LPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467
           LPE  + RH +++IPF  GPR C+G ++             R FR
Sbjct: 432 LPEEVKKRHPFTFIPFGEGPRICIGLRFGLMQTKVGLITLLRKFR 476


>UniRef50_Q16TD6 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 519

 Score =  126 bits (305), Expect = 1e-27
 Identities = 106/420 (25%), Positives = 184/420 (43%), Gaps = 41/420 (9%)

Query: 72  LGEGLLISS-GPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDV 128
           LG+GL+    G  WR  RK++ P F   IL  FV I +  +  +V+ L   ++    FD+
Sbjct: 111 LGKGLITEQRGEIWRRSRKLLNPAFSTRILNEFVPIMDSRARKMVKSLAVLADDKTEFDI 170

Query: 129 HDYMSGTTVDILLETAMGISRKTQDESG-FDYAMAVMKMCDIIHQRHYKFWMRSEIVFKL 187
               +  T++++  T MG   K ++  G  +Y   +  +   I +R          V++ 
Sbjct: 171 LPITAQCTLEMVFSTTMGC--KMEERPGEREYVRCLEGLMTCIGERILNIDRYLGPVYRF 228

Query: 188 TSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTL 247
           T  ++         +G T K+I+ +K   + N    II   +       G + + N    
Sbjct: 229 TKAYQVDKVCRDTCNGFTEKIIQERKRE-MANINNNIIDERMSAAEIDDGRVKSMN---F 284

Query: 248 SDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGH 307
            D +    R D         G      F+D          +++SDH     + +I+  G+
Sbjct: 285 LDQILTIQRPD---------GTN----FVD----------DEVSDH-----LYSIVGAGN 316

Query: 308 DTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRL 367
           +T+    S+    L +   +QA+V  E+ Q+F       T     ++ Y E  + E+LRL
Sbjct: 317 ETSTLTISYTCLFLAMDHQIQAKVCSEIKQVFPSHHTEVTPEALKQLIYTEMALKETLRL 376

Query: 368 YPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKD-PEVFNPDNFLPEN 426
            P VP  AR   + + +      IP         F LHR+  ++ D PE F+P+ F PEN
Sbjct: 377 CPAVPFAARSNVKPIELD--GIHIPQRQIFCFNFFALHRRKDFWGDEPEQFDPNRFSPEN 434

Query: 427 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK 486
           ++NRH Y+Y+PFS G R+C+G +YA            +NF   + +  ++ + +  I +K
Sbjct: 435 SRNRHPYAYLPFSGGFRNCIGGRYAINSLKIMLLRILQNFHMDTSLKREDMRFRWAITMK 494


>UniRef50_UPI0000D56467 Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 470

 Score =  126 bits (304), Expect = 1e-27
 Identities = 75/247 (30%), Positives = 131/247 (53%), Gaps = 13/247 (5%)

Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319
           DF D++     ++  FL+ +++ S+N T    D +I EE  T++    +TTA   + VL 
Sbjct: 232 DFPDDS----MRKKHFLNNLLKMSENMT----DDDILEETQTMLVAASETTALTMATVLL 283

Query: 320 LLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLN 379
            L I   VQ ++Y+EL  I  ++D   T     +M YLE VI E++R+ P VP I R++ 
Sbjct: 284 TLAIFPQVQEKIYEELDAILWNTDE-ITLEHINKMVYLEAVIKETMRILPTVPFINRRMT 342

Query: 380 RDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFS 439
            D+ ++  + V+P G+ ++I    +H  P  +++P+ F+P+ FL E   NR   +++PF 
Sbjct: 343 EDLHLN--DCVVPTGSNIIISIKNIHDSPLLWENPDKFDPERFLTERDPNRSRCAFMPFG 400

Query: 440 AGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEK--EFKLQGDIILKRAEGFQMKVEP 497
            GPR+C+G K+A            +NF     + +   E +   +I+ K  +G+++K   
Sbjct: 401 YGPRNCIGFKFAMLSMKVMMASLLKNFTFEPAVYKSIAEIECFYNIVAKPKKGYKVKFSE 460

Query: 498 RKRVPTN 504
           RK    N
Sbjct: 461 RKLYNNN 467



 Score = 95.1 bits (226), Expect = 4e-18
 Identities = 64/188 (34%), Positives = 91/188 (48%), Gaps = 10/188 (5%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           + ++WLG  LI      +D EIIL+      K     F  P   EGLL +   KW+SHRK
Sbjct: 39  LFKIWLGQDLIFVTSRPEDCEIILSKC--FTKGKFATFMDPIFWEGLLTAPAIKWKSHRK 96

Query: 90  MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILLETAMGIS 148
           +I P+F+I IL SF+G+FN++S  +VEK++   G  + DV  ++   T+DI  ET M I 
Sbjct: 97  IINPSFNIQILNSFIGVFNKHSKKLVEKMRKHAGSDSVDVSYWLFRNTIDISCETLMDID 156

Query: 149 R---KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLT 205
               K Q+E    Y    +K       R    W   E ++K +   K        I    
Sbjct: 157 ADLIKGQEE----YIDDCIKAEKYSSTRMIGVWYHPEFIWKHSPLGKLTKATSDKILDFV 212

Query: 206 NKVIKNKK 213
            K+IK KK
Sbjct: 213 RKIIKLKK 220


>UniRef50_Q06GC7 Cluster: Cytochrome P450; n=1; Rhodococcus sp.
           NS1|Rep: Cytochrome P450 - Rhodococcus sp. NS1
          Length = 497

 Score =  126 bits (304), Expect = 1e-27
 Identities = 70/226 (30%), Positives = 117/226 (51%), Gaps = 8/226 (3%)

Query: 276 LDLMIESSQNGTNKI-SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           L  M+++    T ++ SD  I+ +V T +  GH+TTA   SF L  L ++ ++  R  +E
Sbjct: 274 LQRMLDNPDPETGEMMSDQSIRNQVLTFLIAGHETTAGLLSFALHYLSLNPEIVERAREE 333

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           + Q+ G    P  F    +++Y+ R+I E+LRL+P  P   RK  +  T+    Y I  G
Sbjct: 334 IEQVLGTDGAPVRFEQVAKLRYVRRIIDETLRLWPSGPAFFRKARQATTLD--GYPIRKG 391

Query: 395 TTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXX 453
            T+++    LHR P  + +DPE F+PD FLP   + R  ++Y PF  G R+C+GR++A  
Sbjct: 392 ETILVVLLALHRDPALWGEDPERFDPDRFLPAAVRARPAHAYKPFGVGARACIGRQFALH 451

Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILK-RAEGFQMKVEPR 498
                       F     +P  +++L  + +L  R E  ++ + PR
Sbjct: 452 EAVLALAQILTRF---DIVPTADYELTVEELLTIRPENLKLAMRPR 494


>UniRef50_UPI000038CC01 Cluster: COG2124: Cytochrome P450; n=1;
           Nostoc punctiforme PCC 73102|Rep: COG2124: Cytochrome
           P450 - Nostoc punctiforme PCC 73102
          Length = 451

 Score =  126 bits (303), Expect = 2e-27
 Identities = 70/229 (30%), Positives = 118/229 (51%), Gaps = 5/229 (2%)

Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327
           GEK       LM    +    ++ D  +++EV T+M  GH+TTA   S+   LL  +  V
Sbjct: 220 GEKTNDLLTMLMEAKDEQTLQQMDDKLLRDEVATLMLAGHETTANTLSWTWMLLAQNPGV 279

Query: 328 QARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387
           + ++  EL Q+     +  T  D  ++ Y +++I ES+RLYPPVP++ R+   D  I   
Sbjct: 280 REKLESELNQVL--QGKLPTLEDLGQLVYTQQIIKESMRLYPPVPLMGREAAVDTQIG-- 335

Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447
           +Y IP G  ++I  +++HR PKY+++PE F P+ +  E  +      YIPF  GPR C+G
Sbjct: 336 DYEIPQGMAIMISQWVMHRHPKYFENPEAFQPERWTQEFEKQLPKGVYIPFGDGPRICIG 395

Query: 448 RKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496
           + +A            + F+ I  +P      Q  I L+   G +++++
Sbjct: 396 KGFAQMEAALLLATIAQRFQ-IDLVPGYPIVPQPSITLRPENGLKVQLK 443



 Score = 55.6 bits (128), Expect = 3e-06
 Identities = 30/116 (25%), Positives = 58/116 (50%), Gaps = 2/116 (1%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86
           +G+++ + LG      +++ + IE +L +     K+   R  K  LGEGLL + G  W  
Sbjct: 37  YGDIVPLQLGLTPSCLIINPEYIEEVLKNRNDFIKSRGLRALKSLLGEGLLSAEGESWFW 96

Query: 87  HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLE 142
            R++  P FH   +  +     + +N +V+      G+T D+H+ M   T+ I+++
Sbjct: 97  QRRLAQPVFHQKRINGYSQTMVEYTNRMVQTWHD--GETHDIHEDMMRLTLQIVMK 150


>UniRef50_Q964R1 Cluster: Cytochrome P450 6j1; n=1; Blattella
           germanica|Rep: Cytochrome P450 6j1 - Blattella germanica
           (German cockroach)
          Length = 501

 Score =  126 bits (303), Expect = 2e-27
 Identities = 59/197 (29%), Positives = 102/197 (51%), Gaps = 1/197 (0%)

Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329
           +KR   LD ++E   + T+K+   +   +    +  G  T++   +F L  L +HQD+Q 
Sbjct: 270 EKRNDLLDYLMELRTSETSKLDGDDFVAQAFGFLVAGFHTSSMTLTFALYELSVHQDIQT 329

Query: 330 RVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY 389
               E+  +     +  T+    +MKYL+ V+ E+LR YP +P + R+   D  + T++ 
Sbjct: 330 TARTEIKDVLEHHKKKVTYYSIKDMKYLDMVVNETLRKYPAIPFLDRRCQEDYPL-TQDL 388

Query: 390 VIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449
           ++PAGT V I  + LH   KY+  P  F+P+ F  +N QN  +++Y+PF  GPR+C+G +
Sbjct: 389 MLPAGTGVYIPVYALHHDSKYFPSPAKFDPERFSEKNKQNIPHFAYMPFGEGPRNCIGMR 448

Query: 450 YAXXXXXXXXXXXXRNF 466
           +              NF
Sbjct: 449 FGSMQVKAALIHILSNF 465


>UniRef50_Q0IG08 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 526

 Score =  125 bits (302), Expect = 2e-27
 Identities = 106/421 (25%), Positives = 185/421 (43%), Gaps = 44/421 (10%)

Query: 72  LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHD 130
           LG GL+   G KWR  R M++P F  N ++  V +  + + ++   ++ E  +  +DV +
Sbjct: 116 LGNGLISLEGQKWRDMRAMLSPMFTGNKIRHMVPLVGKCAEDLCRFVERETDEVEWDVRE 175

Query: 131 YMSGTTVDILLETAMGISRKT--QDESGFD-YAMAVMKMCDIIHQRHYKFWMRSEIVFKL 187
            ++   V+++   A GI   +    ++ FD  A  +M   D+          R    F L
Sbjct: 176 LLAKCLVEVIGSCAFGIEVDSFNDPDNEFDRVAKYLMNQSDV----------RKVARFLL 225

Query: 188 TSFFKQQTKLLG--IIHGLTNKVIKNK-KETYLENKAKGIIPPTLEEFTHHSGEILANNA 244
              F +  K  G  +      ++ +    ET L+ ++ G+  P L +       +LA   
Sbjct: 226 IMVFPKMCKQFGMELFDDKYKRLFRRLVSETMLKRESDGVSRPDLIQLL-----MLARRG 280

Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMF 304
           K  +D                DV  +   A  D +   + +     SD E+  +      
Sbjct: 281 KLEAD---------------KDVEGESFAAANDYLETGTDDVKRSWSDDELTAQAVIFFA 325

Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364
            G DTT+   SF L  L IH ++Q R+++E+  +   SD   ++     ++YL+ VI ES
Sbjct: 326 AGFDTTSTLLSFTLMELAIHPEIQDRLFEEIKSV-QRSDSVISYEQIQSLEYLDAVISES 384

Query: 365 LRLYPPVPVIARKLNRDVTI-----STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNP 419
           LR +PP+    RK  +D  +      +  + I  G +V +  +  H  PKY+ +PE F+P
Sbjct: 385 LRKWPPLTATDRKCTKDYLMVDPEDGSPMFSIEEGYSVWVPIYCFHHDPKYFPNPEKFDP 444

Query: 420 DNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKL 479
           D F   N    +  +Y+PF  GPR+C+G ++A            R+FR +   P+ +  L
Sbjct: 445 DRFNRVNRHQLNPAAYMPFGVGPRNCIGSRFALMSAKMILLRLLRSFR-VEVCPKTDTTL 503

Query: 480 Q 480
           Q
Sbjct: 504 Q 504


>UniRef50_UPI00015B4AC4 Cluster: PREDICTED: similar to cytochrome
           P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 521

 Score =  124 bits (300), Expect = 4e-27
 Identities = 62/209 (29%), Positives = 108/209 (51%), Gaps = 6/209 (2%)

Query: 271 KRLAFLDLMIESSQNGT----NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326
           KR  F+DL+IE    GT    N + ++ I  +       G++T++   +F L  L ++ +
Sbjct: 286 KRHDFMDLLIELKNRGTLELDNVLDENTIAAQAFVFFVAGYETSSNTIAFCLYELAVNPE 345

Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386
           +Q +   ++       D   T+    +MKYL+ VILE+LR YPP P+++R+      +  
Sbjct: 346 IQEKARRDIIDALDKRDSKLTYDAVQDMKYLDMVILETLRKYPPAPLLSRRCEYPYKLPG 405

Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446
            +  +  G  VVI  + +H  PK+Y +P+ F P+ F  E  + RH Y+++PF  GPR+C+
Sbjct: 406 SDVELSKGMRVVIPIYAIHHDPKHYPEPDKFRPERFGDEEKRARHPYTFLPFGEGPRNCI 465

Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEK 475
           G ++A            R ++   E+ EK
Sbjct: 466 GTRFALLQTKVGVITFLRKYQV--EVCEK 492


>UniRef50_A3RK60 Cluster: Cytochrome P450; n=2; Liposcelis
           bostrychophila|Rep: Cytochrome P450 - Liposcelis
           bostrychophila
          Length = 527

 Score =  124 bits (299), Expect = 6e-27
 Identities = 102/384 (26%), Positives = 170/384 (44%), Gaps = 31/384 (8%)

Query: 72  LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK-SEVGKTF-DVH 129
           L   L   SG KWR+ R  + PTF    +K    I  ++   ++  L+ + + K   ++ 
Sbjct: 121 LSAHLFSISGSKWRNLRAKLTPTFTSGKMKMMFPILVESGREMISILEPNAINKDIVEMK 180

Query: 130 DYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTS 189
           D ++  T D++   A GI   +      ++     KM   I +  +   +R+       S
Sbjct: 181 DILARFTTDVIASCAFGIDSNSLKNPDTEFR----KMGRKIVEPSFANILRN------FS 230

Query: 190 FFKQQTKLLGIIHGLTNKVIKNKK-ETYLENKAKGIIPPTLEEFTHHSGEILANN-AKTL 247
           F    T +         K+ K K    YL N   G +  T++        +  N+  + L
Sbjct: 231 FMAMPTLV---------KIFKIKLIPEYLANFFMGSVRETMDY--REQNNVKRNDFMQLL 279

Query: 248 SDTVFKGYRDDLD-FNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEG 306
                KG  DD+D   ++ D G + +    +L +E +++   K S  E   +       G
Sbjct: 280 IQLKNKGKLDDVDEIKEKTDDGNEIK----ELEVEENRSD-QKFSFEEAAAQAFIFFVAG 334

Query: 307 HDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLR 366
            +T++      L  L +  ++Q +V +E+  + G  +   T+     M YL  VI E+LR
Sbjct: 335 FETSSTTMVLALYELALQPEIQEKVRNEIKTVLGKHNGKITYEAAFGMDYLGNVIDETLR 394

Query: 367 LYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPEN 426
            YP   VI R+ N+D  I   + VIP GT+  I  + LH   KY+ +PE F+PD F  E 
Sbjct: 395 KYPVAGVIIRQCNKDYKIPDSDMVIPKGTSTHIPIYSLHYDSKYFPNPEKFDPDRFTEEV 454

Query: 427 TQNRHYYSYIPFSAGPRSCVGRKY 450
              R  Y+Y+PF  GPR C+G ++
Sbjct: 455 KSQRPRYAYLPFGEGPRHCIGMRF 478


>UniRef50_Q9PVE8 Cluster: Cytochrome P450 3A30; n=4;
           Percomorpha|Rep: Cytochrome P450 3A30 - Fundulus
           heteroclitus (Killifish) (Mummichog)
          Length = 496

 Score =  124 bits (299), Expect = 6e-27
 Identities = 75/238 (31%), Positives = 124/238 (52%), Gaps = 14/238 (5%)

Query: 269 EKKRLAFLDLMIESSQNG----TNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 324
           +K R+ FL LMI+S +N        ++DHEI  +    +F G++T+++  +F+   L  +
Sbjct: 264 QKSRVDFLQLMIDSQKNSGAQQDKSLTDHEILSQSMIFIFAGYETSSSSLTFLAYNLATN 323

Query: 325 QDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR--DV 382
            +V  ++ +E+   F +   P  +   +EM+YL+ VI ESLRL+P    IA +L R    
Sbjct: 324 PEVMKKLQEEIDATFPNK-APVHYQPLMEMEYLDCVINESLRLFP----IAARLERVAKA 378

Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442
            +     VIP    V+I T+ LHR P+ + +PE F P+ F  +N  N   Y Y+PF +GP
Sbjct: 379 AVEINGVVIPKDMVVMIPTWPLHRDPEIWPEPEAFKPERFSKKNKDNIDPYIYMPFGSGP 438

Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDI--ILKRAEGFQMKVEPR 498
           R+C+G ++A            + + + S   E E   + DI  +L      Q+K+ PR
Sbjct: 439 RNCIGMRFALVLIKLAVVEILQQY-SFSVCKETEVPFEMDIQGLLAPKRPIQLKLVPR 495



 Score = 42.3 bits (95), Expect = 0.029
 Identities = 27/144 (18%), Positives = 64/144 (44%), Gaps = 5/144 (3%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHV--HIDKATEYRFFKPWLGEGLLISSGPKW 84
           +G V  ++ G + ++ + D + I+ +L             +R   P L + + I+   +W
Sbjct: 67  YGKVWGIYDGRQPVLCVTDPEIIKAVLVKECLSFFTNRRNFRLNGP-LYDAVSIAEDDQW 125

Query: 85  RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLE 142
           +  R +++P+F    LK    I   +S N++  +K +  K    D+ ++    ++D++  
Sbjct: 126 KRIRSVLSPSFTSGRLKEMFEIMKNHSANLIRSMKKKADKDEPLDLKEFFGSYSMDVVTS 185

Query: 143 TAMGISRKTQDESGFDYAMAVMKM 166
           TA  +   + +     +   + KM
Sbjct: 186 TAFSVDIDSLNNPSDPFVTNIKKM 209


>UniRef50_Q9VGB3 Cluster: Probable cytochrome P450 313a3; n=2;
           Drosophila melanogaster|Rep: Probable cytochrome P450
           313a3 - Drosophila melanogaster (Fruit fly)
          Length = 492

 Score =  124 bits (298), Expect = 7e-27
 Identities = 73/212 (34%), Positives = 112/212 (52%), Gaps = 5/212 (2%)

Query: 280 IESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIF 339
           IE  +NG  ++S  E++ E  + +    +TT       L LL +  + Q  VY EL ++F
Sbjct: 274 IELHRNG--EMSREEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELF 331

Query: 340 GDS-DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVV 398
             + D   T+ D   M +LERV+ E+LRL P VP   R+  RD  +S+   VIP G  + 
Sbjct: 332 PVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPRETIRDFRLSS-GVVIPKGVGIG 390

Query: 399 IGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXX 457
           I  F  HR   ++  DP  FNPD+FLP+N ++RH Y+YIPFS G R+C+G KY       
Sbjct: 391 IDIFATHRNRDHWGTDPSSFNPDHFLPDNVRDRHPYAYIPFSKGRRNCIGWKYGLMSSKL 450

Query: 458 XXXXXXRNFRTISEIPEKEFKLQGDIILKRAE 489
                 RN +  +    ++ +   +I ++ A+
Sbjct: 451 ALSKILRNCKVSTSFRYEDLEFVDNIGMELAQ 482



 Score = 52.4 bits (120), Expect = 3e-05
 Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 2/139 (1%)

Query: 14  QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY-RFFKPWL 72
           ++ +++   Y   +G+   VW+G    V   D    E I  S   +++++ + +      
Sbjct: 52  KRKMSIRTKYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCT 111

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDY 131
           G+GLL     KW   RK + P F  N+L SF+ IFN  +  +V  L S VG+    V D 
Sbjct: 112 GDGLLSLEASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEKKVRDD 171

Query: 132 MSGTTVDILLETAMGISRK 150
           +   +  I  +T +G   K
Sbjct: 172 IVRWSFRIATQTTVGTDVK 190


>UniRef50_Q3E385 Cluster: Cytochrome P450; n=3; Chloroflexus|Rep:
           Cytochrome P450 - Chloroflexus aurantiacus J-10-fl
          Length = 452

 Score =  123 bits (297), Expect = 1e-26
 Identities = 67/199 (33%), Positives = 110/199 (55%), Gaps = 6/199 (3%)

Query: 276 LDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           L++++ +    T + +S  +I++EV TI   GH+TTA   S++L LL  H + + ++  E
Sbjct: 231 LEMLVTARDADTGEQMSPKQIRDEVMTIFLAGHETTAGTLSWILHLLAHHGESERKLRAE 290

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
              + G   R  T AD  ++ Y   VI E+LRLYPP  +++R L    T+   +Y +PAG
Sbjct: 291 YATVLGG--RNPTPADLPQLPYNRMVIDETLRLYPPTWILSRVLVEADTLG--DYELPAG 346

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454
             V +  ++ HR P ++ + E F+P+ F P   + RH ++YIPF  GPR C+G  +A   
Sbjct: 347 AVVALSPYVTHRHPDFWPNAESFDPERFRPTAIEQRHKFAYIPFITGPRQCIGNNFALME 406

Query: 455 XXXXXXXXXRNFRTISEIP 473
                    ++FR +S IP
Sbjct: 407 MQLILPMILQHFR-VSAIP 424



 Score = 41.9 bits (94), Expect = 0.038
 Identities = 27/124 (21%), Positives = 55/124 (44%), Gaps = 3/124 (2%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86
           +G+++R+ LG   +   +  D I+ I   +   +    Y      LG+GL+ S+G  W  
Sbjct: 38  YGDLVRLSLGRHTMYLAIHPDMIKRITQENWK-NYIKRYPAMDEILGQGLVTSNGAHWLR 96

Query: 87  HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETA 144
            R+++ P FH   +     I  + +  ++ + +  +   +  D+   M   T  I++ T 
Sbjct: 97  QRRLMQPAFHHQRIARMASIMVEEAEQMLARWETYARTRQPVDIQHEMMLLTQKIIVRTM 156

Query: 145 MGIS 148
            G S
Sbjct: 157 FGTS 160


>UniRef50_Q17PE0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 462

 Score =  123 bits (297), Expect = 1e-26
 Identities = 73/239 (30%), Positives = 124/239 (51%), Gaps = 5/239 (2%)

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
           DE+  G  K   FLD ++ +++ G     D EI+  V T++  G+DT+    ++   LLG
Sbjct: 224 DEDQDGYHKPQIFLDQILSANRAG-KPFDDEEIQHNVRTMIAAGNDTSGQLMAYACLLLG 282

Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLE-MKYLERVILESLRLYPPVPVIARKLNRD 381
           ++  +Q +VY E+ ++   + + +   + L+ + Y E  + E LRL P  P IAR LN  
Sbjct: 283 MYPHIQEKVYSEIIELIPLTRKESISVEQLKTLTYTEMFMFECLRLCPIAPNIAR-LNM- 340

Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSA 440
             I  +   IPAG    I  + LHR+   +  D E F+P+ F PE +  RH Y+++PFS 
Sbjct: 341 TPIELEGITIPAGHIFFISFYSLHRRKDIWGPDAEQFDPERFSPERSVGRHLYAFLPFSG 400

Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
           G R+C+G +YA            R +R  +++   + K + D++L       +K+E R+
Sbjct: 401 GSRNCIGWRYAMMSMKLMLVYLLREYRFRTDLKLSDLKFKFDMMLVLVFEHWVKIEKRR 459



 Score = 65.3 bits (152), Expect = 4e-09
 Identities = 44/169 (26%), Positives = 82/169 (48%), Gaps = 5/169 (2%)

Query: 59  IDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL 118
           ++K   Y FFK  L  GL  +    W+  RK +  TF++ IL SF+ IF + S  +V +L
Sbjct: 58  LEKPFLYDFFK--LDYGLFSAHYGLWKQQRKALNSTFNLKILHSFIPIFEECSRKLVNRL 115

Query: 119 KSEVG--KTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYK 176
           ++ VG  K  ++  ++S  T++++  T +G+    Q ESG  +   + ++ DI+ +R   
Sbjct: 116 QNHVGCSKPINLAQFVSQCTLEMVCGTTLGMEH-LQQESGSRFLHHIERVMDIMGERILS 174

Query: 177 FWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGII 225
             M+   ++  T  F Q+   L +      ++I   +     N+    I
Sbjct: 175 IPMQITALYFFTPMFWQEMHSLKMNRQYAAEIIDEGRRKMKANEQSNTI 223


>UniRef50_A7RNE6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 498

 Score =  123 bits (297), Expect = 1e-26
 Identities = 64/205 (31%), Positives = 107/205 (52%), Gaps = 3/205 (1%)

Query: 294 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLE 353
           E+ ++  T    G +TTA   SF L  +G+H D+  +V +E+ ++ G       + D   
Sbjct: 297 ELLDDFVTFFIAGQETTANQLSFALLEIGLHPDITHKVVEEVDKVIGSHVDFVEYDDLAN 356

Query: 354 MKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKD 413
           + Y+ +V+ E+LR YPP   + R    ++T++   +VIPAGT + +  +  H  P  +KD
Sbjct: 357 LSYMTQVLKETLRKYPPAAGVIRHSPEEITLN--GHVIPAGTGIGLNIYGAHHNPTNWKD 414

Query: 414 PEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIP 473
           PEVF+P+ F  EN  N   ++++PFS GPRSC+G+ +A            + FR I   P
Sbjct: 415 PEVFDPERFNAENAPNIKPFTFLPFSLGPRSCIGQHFAQFEAKVLLARFLQKFR-IKLCP 473

Query: 474 EKEFKLQGDIILKRAEGFQMKVEPR 498
            +   L+    L+  +G    +E R
Sbjct: 474 GQTTALRQTGTLQPRDGVMCLIEKR 498


>UniRef50_UPI0000D555E9 Cluster: PREDICTED: similar to Cytochrome
           P450 6a2 (CYPVIA2) (P450-B1); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Cytochrome P450 6a2
           (CYPVIA2) (P450-B1) - Tribolium castaneum
          Length = 514

 Score =  123 bits (296), Expect = 1e-26
 Identities = 67/214 (31%), Positives = 107/214 (50%), Gaps = 3/214 (1%)

Query: 286 GTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRP 345
           GT+   D E   +       G +TT+   SF L  +  ++ ++ +   E+ ++ G     
Sbjct: 300 GTSLTLD-EAAAQAFIFFLAGFETTSTTISFALFEMARNESIRTKARTEINKVLGKHGGK 358

Query: 346 ATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLH 405
            T+  T+EM+YL+ VI E+LR YPP PV  RK  +   +   + +I  G +V+I  + LH
Sbjct: 359 LTYEATMEMEYLDTVISETLRKYPPAPVFLRKCTKTYRVPDTDVIIEEGLSVLIPAYGLH 418

Query: 406 RQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRN 465
           R P+Y+ DPE F+PD F  +N      Y+YIPF  GPR C+G ++A            ++
Sbjct: 419 RDPEYFPDPETFDPDRFNEDNRSKIWDYTYIPFGDGPRICIGMRFAMIQIKIALALILKS 478

Query: 466 FR-TISEIPEKEFKLQGD-IILKRAEGFQMKVEP 497
           F   +SE      K++   IIL    G  + + P
Sbjct: 479 FEFPLSEKTILPMKMENSGIILAPIGGIWLNLIP 512


>UniRef50_Q5KR92 Cluster: Cytochrome P450; n=1; Hodotermopsis
           sjoestedti|Rep: Cytochrome P450 - Hodotermopsis
           sjoestedti
          Length = 528

 Score =  123 bits (296), Expect = 1e-26
 Identities = 98/432 (22%), Positives = 190/432 (43%), Gaps = 35/432 (8%)

Query: 74  EGLLIS-SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG--KTFDVHD 130
           +G L S SG KWR+ R  + P F    LK+  G   +   ++   L+      +T ++ D
Sbjct: 122 DGHLFSLSGAKWRNLRVKMTPIFTSGKLKTMFGTVVECGKDLQVALQKAANNEETVEIKD 181

Query: 131 YMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSF 190
           +++  + D++   A GI                   C+ + + + +F      +F+    
Sbjct: 182 FLARYSTDVISSCAFGI------------------QCNCLKKPNAEFRNWGRRIFE--PH 221

Query: 191 FKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDT 250
           F+Q  +L  I++ L   ++   K + +       +     +  + + E   NN+   +D 
Sbjct: 222 FRQ--RLTSILNMLYPSLVYTLKLSLIPKD----VGNYFRKMVNETVEYRENNSVKKND- 274

Query: 251 VFKGYRDDLDFNDENDVGEKKRLAFLDLMIES-SQNGTNKISDHEIKEEVDTIMFEGHDT 309
            F      L  N      E+  + F++   E    N +  ++ + I  +       G +T
Sbjct: 275 -FMQMMIQLK-NKTLGTAEENDMNFVEKETEELKSNASFDVTMNVIAAQAFVFYVAGFET 332

Query: 310 TAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYP 369
           ++   +F L  L ++ D+Q R++ E+  +        T+    EM+YL++V+ E+LR YP
Sbjct: 333 SSTTMTFCLYELALNPDIQERLHAEIDTMLEKHGGNITYESIFEMEYLDKVVNETLRKYP 392

Query: 370 PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQN 429
           PV ++ R+  + + +   +  +  G  V++    LH  PKYY DPE F+P+ F  E  + 
Sbjct: 393 PVVILTRECTKPIKLRRTDVTLEKGLQVLLPVLGLHHDPKYYPDPERFDPERFSEEEKKK 452

Query: 430 RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF--RTISEIPEKEFKLQGDIILKR 487
           R ++S++PF  GPR C+G ++A             N+  R   + P      +  ++L  
Sbjct: 453 RPHFSFLPFGEGPRMCIGMRFALMQTKVGLISLLSNYEVRVSEKTPVPLVFEKSALVLTA 512

Query: 488 AEGFQMKVEPRK 499
           A G  + +E R+
Sbjct: 513 AGGMWLMIENRQ 524


>UniRef50_UPI00015B480C Cluster: PREDICTED: similar to cytochrome
           P450 monooxygenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to cytochrome P450 monooxygenase -
           Nasonia vitripennis
          Length = 730

 Score =  122 bits (295), Expect = 2e-26
 Identities = 60/217 (27%), Positives = 115/217 (52%), Gaps = 9/217 (4%)

Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKE-----EVDTIMFEGHDTT 310
           R+ +++  +N+V   ++   +D++++  +N   + +D EI E     +       G DTT
Sbjct: 485 RETMEYRKKNNV---RKHDIVDVLMDIKEN-PEQFNDEEITELFLTAQAFVFFIAGFDTT 540

Query: 311 AAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPP 370
           +   S  +  L ++ D+Q ++  E+   + +++   ++     MKYL++V  E+LR YPP
Sbjct: 541 SNAMSHAMYELALNPDIQEKLRQEVNATYSENNGKFSYDSVRNMKYLDKVFKETLRKYPP 600

Query: 371 VPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNR 430
              ++RK   + + S     IP GT+++I T+ +H  P YY DP+ F+P+ F   N  NR
Sbjct: 601 AFTLSRKSMNNHSFSGTKITIPKGTSLMIPTYAIHHDPSYYPDPDKFDPERFDEGNANNR 660

Query: 431 HYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467
            + +++PF  GPR+C+G ++A            R F+
Sbjct: 661 IHMTFLPFGDGPRNCIGERFANNQFKVGIAMTVRKFK 697


>UniRef50_UPI0000D5558E Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=2; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 495

 Score =  122 bits (295), Expect = 2e-26
 Identities = 63/225 (28%), Positives = 110/225 (48%), Gaps = 3/225 (1%)

Query: 274 AFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYD 333
           + L+ + E      + ++  +  + + T M    DT ++  +F   +LG +  +Q  V  
Sbjct: 272 SMLESIAEMVMENPDCLTMQDCTDHLMTFMATSQDTQSSAVAFTCMMLGAYPHIQDLVVQ 331

Query: 334 ELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPA 393
           EL ++ G         D  ++KYLE  + ES+RL+P  P I R    D        VIP 
Sbjct: 332 ELREVMGKKTS-LDLTDVSQLKYLEMCLKESMRLFPVGPFIFRDTTEDFQFD--KMVIPE 388

Query: 394 GTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXX 453
           G TV++  +  HR P++++ P+ F P++F PE    RH  ++IPFSAGPR C+ + Y+  
Sbjct: 389 GVTVILSIYHAHRSPEHWEKPDEFYPEHFAPEAMSKRHPCAFIPFSAGPRRCIAQHYSYT 448

Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
                      N+        ++ KL  DI ++  +G+ +K++ R
Sbjct: 449 YMKILLATIVLNYEIECRFKAEDVKLIADISIRPQQGYLIKLKDR 493



 Score =  118 bits (284), Expect = 4e-25
 Identities = 61/209 (29%), Positives = 114/209 (54%), Gaps = 8/209 (3%)

Query: 14  QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLG 73
           +++ N  +     + + +R+W+G KL++F+ D + +++IL S     K+  YRF +P+LG
Sbjct: 51  EEIFNNFMAATAPYPSPVRLWVGPKLVLFVKDPNQLQLILQSSKITTKSFLYRFLEPFLG 110

Query: 74  EGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL-KSEVGKTFDVHDYM 132
           +GL  SSGP+ + HRK++ P F   +++ +  +F ++S   VE L K+  G  F++  ++
Sbjct: 111 KGLFTSSGPRQKHHRKLLQPLFSQRMIEGYCHLFQKHSKKFVEDLRKNANGPEFNISTFL 170

Query: 133 SGTTVDILLETAMGISRKTQDESGFDY---AMAVMKMCDIIHQRHYKFWMRSEIVFKLTS 189
             T      E  M +  + QD    DY      V K  +I+  R   FW+  +I FKL+S
Sbjct: 171 QFTA----FEATMDLLLEDQDTHSIDYNEIPNYVRKFYEIVFTRVKSFWLHLDIFFKLSS 226

Query: 190 FFKQQTKLLGIIHGLTNKVIKNKKETYLE 218
           ++++QTKL  +   + N++ +      +E
Sbjct: 227 YYREQTKLQSLATTVINEITETNVPKIIE 255


>UniRef50_Q964R0 Cluster: Cytochrome P450 6k1; n=1; Blattella
           germanica|Rep: Cytochrome P450 6k1 - Blattella germanica
           (German cockroach)
          Length = 524

 Score =  122 bits (295), Expect = 2e-26
 Identities = 72/227 (31%), Positives = 115/227 (50%), Gaps = 24/227 (10%)

Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTI-- 302
           K  ++ + K + D ++F + N +    R  F+DL+I+    GT    D E+ E+VD I  
Sbjct: 246 KETTEFLRKVFWDTINFRESNKIS---RDDFMDLLIQLKNKGTIDNEDGEVTEKVDKIDK 302

Query: 303 ---MFE----------------GHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD 343
              +FE                G +T A   SF L  L +  D+Q R+  E+  +   S+
Sbjct: 303 DSHLFEFTGDNLVSQPALFFTAGFETNATTLSFTLYELSLQPDLQNRLRSEIAGVMKTSN 362

Query: 344 RPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFM 403
              T+ D   M YL  V+ E+LR YPP+P++ R   +D  +   + +I   T V I    
Sbjct: 363 GKPTYEDVFGMPYLHMVVSETLRKYPPLPLLDRVCLQDYKVPGTDLIIERDTPVFIALLG 422

Query: 404 LHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKY 450
           LHR P+YY +PE ++P+ F  EN + R  Y+Y+PF  GP +C+G ++
Sbjct: 423 LHRDPQYYPNPERYDPERFSEENKRQRKAYTYLPFGEGPHNCIGLRF 469


>UniRef50_UPI0000DB7C31 Cluster: PREDICTED: similar to Probable
           cytochrome P450 6a14 (CYPVIA14); n=1; Apis
           mellifera|Rep: PREDICTED: similar to Probable cytochrome
           P450 6a14 (CYPVIA14) - Apis mellifera
          Length = 490

 Score =  122 bits (294), Expect = 2e-26
 Identities = 69/213 (32%), Positives = 107/213 (50%), Gaps = 5/213 (2%)

Query: 288 NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPAT 347
           NK++  E   +       G +T++   +F L  L  +QD+Q +V +E+ Q     +   T
Sbjct: 279 NKLTMMEAAAQAYVFFLAGFETSSTTVTFCLYELAKNQDIQNKVREEI-QTMIKKNGDLT 337

Query: 348 FADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ 407
           +    +M YL +VI E+LR YPPV ++ R    DV +ST ++ IP GT + I  F LHR 
Sbjct: 338 YNALNDMNYLHKVISETLRKYPPVVILNRICTNDVKLSTTDFCIPKGTCIAIPVFGLHRD 397

Query: 408 PKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA--XXXXXXXXXXXXRN 465
              + +PE F+P+ F  EN + RH Y Y+PF  GPR C+G ++                 
Sbjct: 398 SNIFPNPEKFDPERFSEENIKTRHPYVYLPFGEGPRICIGLRFGLIQTKIAIINALLKNK 457

Query: 466 FRTISEIPEK-EFKLQGDIILKRAEGFQMKVEP 497
           F+     P   EF+ +G +IL    G  + +EP
Sbjct: 458 FKFGPNTPSTLEFE-KGSLILIGKGGIHLNIEP 489



 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 2/70 (2%)

Query: 81  GPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVD 138
           G KWR+ R  + PTF    +K F  I N+  N + + L+ E   G T DV D  +  + D
Sbjct: 108 GKKWRNLRVKLTPTFTSGKIKQFFPILNEAGNILAKYLEEEARKGSTIDVKDIFARYSTD 167

Query: 139 ILLETAMGIS 148
           I++  A GIS
Sbjct: 168 IIMSVAFGIS 177


>UniRef50_Q629N7 Cluster: Cytochrome P450-related protein; n=24;
           Burkholderia|Rep: Cytochrome P450-related protein -
           Burkholderia mallei (Pseudomonas mallei)
          Length = 1373

 Score =  122 bits (294), Expect = 2e-26
 Identities = 69/218 (31%), Positives = 115/218 (52%), Gaps = 6/218 (2%)

Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349
           ++  E+ +EV T+   GH+TT AG ++ L  L  H  V  ++ DEL    G   R  T  
Sbjct: 245 MTQQEVHDEVMTVFLAGHETTGAGLAWALYALAQHPAVLRQLRDELDARLGG--RAPTVQ 302

Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409
           D  ++ YL +V+ E LR+YPP+    R L  D  I    Y IPA ++V +  ++ HR P 
Sbjct: 303 DFEQLPYLSQVVDEVLRVYPPIWGFTRDLVEDDEIG--GYRIPARSSVFMSPYVTHRHPA 360

Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTI 469
           ++++P+ F+P+NF   +   RH + Y PF  G R C+G + A            ++F  +
Sbjct: 361 FWRNPDAFDPENF-ASDAPARHRFVYFPFGGGMRKCIGFQTALLQMRVLVAVVAQHF-DL 418

Query: 470 SEIPEKEFKLQGDIILKRAEGFQMKVEPRKRVPTNVAR 507
           + +P    +L   I L+   G ++ V+PR+R  +++AR
Sbjct: 419 NALPGHPIELGATISLRPVHGIRLIVKPRERQQSHLAR 456



 Score = 51.6 bits (118), Expect = 5e-05
 Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 1/81 (1%)

Query: 17  VNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILN-SHVHIDKATEYRFFKPWLGEG 75
           + + L   Q +G+V R  LG  +   L   D I+ +L  +H +  +   Y  FK + G+G
Sbjct: 27  ITMLLRLHQQYGDVARNRLGPFVTHALAHPDHIQYVLQENHRNYVRGRFYDNFKMFFGDG 86

Query: 76  LLISSGPKWRSHRKMIAPTFH 96
           LL + G  WR HR+++ P FH
Sbjct: 87  LLTTDGEFWRRHRRVVQPLFH 107


>UniRef50_Q27691 Cluster: Cytochrome P450; n=2; Musca domestica|Rep:
           Cytochrome P450 - Musca domestica (House fly)
          Length = 503

 Score =  122 bits (294), Expect = 2e-26
 Identities = 65/223 (29%), Positives = 114/223 (51%), Gaps = 8/223 (3%)

Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIE-SSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGS 314
           R  +++ + N V   K   F+DL++E  ++ G   +S  ++          G +T++   
Sbjct: 257 RQTVEYRERNQV---KCNDFMDLLMEIRAKEGEEGLSFEQMAALTFDFFLAGFETSSTTM 313

Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374
           +F L  L  + ++Q ++  E+  I  DS+   ++    +M +LE+ I E+LRLYP +  +
Sbjct: 314 AFTLYELARNPEIQEKLRTEILDILKDSNDELSYEALQKMSFLEQSISETLRLYPVLATL 373

Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434
            R  NRD  +    ++I     VVI    +H  P+YY++PE FNP+ F  E  + RH  +
Sbjct: 374 VRVANRDYPVPDSQHIIEKDIQVVIPVHAIHHDPEYYENPEEFNPNRFAAEECERRHSST 433

Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR----TISEIP 473
           Y+PF  GPRSC+G ++             R++R     ++EIP
Sbjct: 434 YLPFGDGPRSCIGMRFGKMQTKIGLVSLLRHYRFECCPLTEIP 476


>UniRef50_A7SRX7 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 472

 Score =  122 bits (294), Expect = 2e-26
 Identities = 62/184 (33%), Positives = 105/184 (57%), Gaps = 4/184 (2%)

Query: 270 KKRLAFLDLMIESS--QNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327
           K+    LDLM+ ++  +N + K+SD E+  +    +  G++TT    SFV   L  + DV
Sbjct: 274 KEAKDMLDLMLSAAANENTSKKLSDMEVLAQSLIFLIAGYETTNITLSFVAYSLATNPDV 333

Query: 328 QARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387
           Q ++  E+  ++ + D+  ++     + YL+ VI E+LRLYPP  V +R+  +D  I  K
Sbjct: 334 QEKLQREIDSVWTEEDQMPSYDTVHNLPYLDMVISETLRLYPPGFVASRECTQDCVI--K 391

Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447
            Y    G ++ I  + +H  P+++ DPE F+P+ F  E  Q+R  YSY+PF  GP +C+G
Sbjct: 392 GYRFRKGLSIFIDAYSMHHDPEFWTDPERFDPERFSRECKQSRDPYSYLPFGHGPHNCIG 451

Query: 448 RKYA 451
            ++A
Sbjct: 452 MRFA 455



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 36/133 (27%), Positives = 66/133 (49%), Gaps = 7/133 (5%)

Query: 23  YAQTFGNVIRVWL-GSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSG 81
           Y + +G +  ++L G K  V + D D   I+ N  V    + + R  +P+    +  +  
Sbjct: 77  YYKKYGRLYAMFLVGKKPSVIVGDPD---IVKNIMVKEFSSFQDRPVEPF-NSFMTRAKY 132

Query: 82  PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDI 139
            KW   R  ++P F  + +K  V + N + + ++ KL   ++ G +F VH +  G T+D 
Sbjct: 133 DKWHRIRTSLSPAFSAHKMKLMVPLINSSCDVLINKLTKIADSGTSFFVHKFHQGLTMDT 192

Query: 140 LLETAMGISRKTQ 152
           +L+TA GI  + Q
Sbjct: 193 ILKTAFGIHSEAQ 205


>UniRef50_Q5TXA2 Cluster: ENSANGP00000026709; n=2; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000026709 - Anopheles gambiae
           str. PEST
          Length = 198

 Score =  122 bits (293), Expect = 3e-26
 Identities = 61/181 (33%), Positives = 107/181 (59%), Gaps = 6/181 (3%)

Query: 273 LAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVY 332
           + FLD ++ + Q G   +   EI+  + TI+  G +TTA   +F+L ++ +H +VQ RV+
Sbjct: 1   MVFLDQLLHT-QRGGRDLEMQEIENHLYTIIGAGSETTANQVAFILLMIAMHPEVQDRVH 59

Query: 333 DELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIP 392
           +E+  I+G +    ++       YLE+VI E++R+YP  P+I R+     T+   + ++P
Sbjct: 60  EEIVSIYGRAAPDFSYETISAQTYLEQVIKETMRVYPVAPLIGRETIE--TVKLGDVIVP 117

Query: 393 AGTTVVIGTFMLHRQPKYYKD-PEVFNPDNFLPE--NTQNRHYYSYIPFSAGPRSCVGRK 449
           +G T++I    LHR  + + +   VF+PD F P   + + +H +SYIPF  GPR+C+G +
Sbjct: 118 SGVTLLINILTLHRNKELWGERAHVFDPDRFDPALYDAKKQHPFSYIPFGGGPRNCIGYR 177

Query: 450 Y 450
           Y
Sbjct: 178 Y 178


>UniRef50_A7SCY4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 505

 Score =  122 bits (293), Expect = 3e-26
 Identities = 57/185 (30%), Positives = 99/185 (53%), Gaps = 3/185 (1%)

Query: 285 NGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDR 344
           +G   I+D E+ +   T+   G +TTA   +F +  +G H  ++ R+ DE+ ++ G   R
Sbjct: 290 DGDKPIADEEMIDNFLTLFIAGQETTANQLAFTVYEIGKHPQIEMRIQDEVERVLGGKSR 349

Query: 345 PATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFML 404
              + D   +KY+ + + ESLRL+PP+  ++R   +D+T++  + +IP  T V++  F+ 
Sbjct: 350 -VDYEDLNLLKYVNQTLKESLRLHPPISGLSRMTTKDITLN--DVIIPKDTCVILSQFVT 406

Query: 405 HRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXR 464
           HR P+ + DP+ F+P+ F  EN        Y PFS GPRSC+G   A            +
Sbjct: 407 HRDPEVWNDPDTFDPERFALENVGRISSSMYFPFSLGPRSCIGNYLAQFEAKVIMARLYQ 466

Query: 465 NFRTI 469
            F+ +
Sbjct: 467 QFKVV 471



 Score = 40.7 bits (91), Expect = 0.089
 Identities = 25/117 (21%), Positives = 55/117 (47%), Gaps = 3/117 (2%)

Query: 49  IEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK-WRSHRKMIAPTFHINILKSFVGIF 107
           +E+ L     + ++ ++ F +    +G+L    P+ W+  R M++P FH    K  +G+F
Sbjct: 103 LELDLPKAEQVYQSLKFVFGQRAARDGILTECDPEIWKRKRGMLSPAFHRLWFKDSMGMF 162

Query: 108 NQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMA 162
           N   +  + KL+  +  G+  D+ +  S  T+D++ +       +  D    ++  A
Sbjct: 163 NAVCDKFLVKLEGYASSGEAVDLSEMFSRVTMDVIGKVGFNNDLRATDNDKCEFRAA 219


>UniRef50_Q70AR5 Cluster: Putative cytochrome P450; n=1;
           Streptomyces peucetius|Rep: Putative cytochrome P450 -
           Streptomyces peucetius
          Length = 477

 Score =  121 bits (292), Expect = 4e-26
 Identities = 65/212 (30%), Positives = 109/212 (51%), Gaps = 5/212 (2%)

Query: 291 SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFAD 350
           +D +I++EV      GH+T +   S+   LL ++ + + R+  E+ ++   + R  T  D
Sbjct: 271 TDEQIRDEVSGFFVAGHETVSTALSWTWYLLSLNPESRRRLQAEVDEVL--AGRVPTVDD 328

Query: 351 TLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKY 410
             ++ Y   V+ ES+RLYPP+ V  R    D  I    Y IP G  VV+  ++ HR P++
Sbjct: 329 LPKLTYTTMVLQESMRLYPPIFVYMRCAAEDDVIG--GYHIPEGRWVVVCPYVTHRHPEF 386

Query: 411 YKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTIS 470
           + +PE F P+ F PEN+ NRH  +Y+PF AGPR C+G  +A            + FR + 
Sbjct: 387 WDNPEGFEPERFTPENSANRHRMAYLPFGAGPRKCIGDSFAMLQMPLVVAMIAQRFR-LD 445

Query: 471 EIPEKEFKLQGDIILKRAEGFQMKVEPRKRVP 502
            +  ++   +  I L+  +   M + P +  P
Sbjct: 446 LVEGQQVFPEPAISLRPRDPLMMWLRPNEETP 477



 Score = 35.9 bits (79), Expect = 2.5
 Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 2/63 (3%)

Query: 72  LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVE--KLKSEVGKTFDVH 129
           +G+GL+ + G  W   R++  P FH +IL+ F   F  ++  +++  + ++  G+  D+ 
Sbjct: 109 VGDGLVAAEGTSWLRSRRLTQPAFHRDILRRFGDSFTASTAELLDGWERRARDGEPLDIK 168

Query: 130 DYM 132
             M
Sbjct: 169 SEM 171


>UniRef50_Q1D9Z9 Cluster: Cytochrome P450 family protein; n=1;
           Myxococcus xanthus DK 1622|Rep: Cytochrome P450 family
           protein - Myxococcus xanthus (strain DK 1622)
          Length = 458

 Score =  121 bits (292), Expect = 4e-26
 Identities = 61/177 (34%), Positives = 103/177 (58%), Gaps = 5/177 (2%)

Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           L +M+E+  + T  ++SD ++++EV T++  GH+TTA+  ++ + LL  H  V+  +  E
Sbjct: 240 LQMMMEAHDDDTGERMSDSQLRDEVLTLLLAGHETTASALAWTIMLLSQHPGVRRDMESE 299

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           L +  G   R  T  D   ++   RV+ ESLRLYPP   ++R   ++  +    + IP G
Sbjct: 300 LARELGG--RNPTHEDLPRLELTHRVVDESLRLYPPAWALSRIATKEDLVG--GFRIPKG 355

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
             ++I  ++ HR P  + +PE F+PD FLPE  Q R  +++ PF  GPR C+G ++A
Sbjct: 356 AHLLIAPWVTHRHPSIWDNPEGFDPDRFLPEREQARPRFAWFPFGGGPRQCIGNQFA 412



 Score = 52.8 bits (121), Expect = 2e-05
 Identities = 33/136 (24%), Positives = 63/136 (46%), Gaps = 6/136 (4%)

Query: 24  AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHV--HIDKATEYRFFKPWLGEGLLISSG 81
           A+ +G+V+R+ +G   +V +   D +  +L  H   +  ++  +R  +  LG GLL S G
Sbjct: 42  AREYGDVVRLPMGPADLVLVAHPDGVRHVLQDHARNYSKQSRGFRVLQELLGHGLLTSDG 101

Query: 82  PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDI 139
             W   R++  P FH   +  F       + ++   +  +++ G  F+V +  +  T+ I
Sbjct: 102 DHWLRQRRLAQPAFHRQRVAGFTRTMVDAAADLAATMEARADTGAAFNVAEDFTRLTLRI 161

Query: 140 LLETAMG--ISRKTQD 153
              T  G  +S  T D
Sbjct: 162 ASSTLFGADVSSATHD 177


>UniRef50_Q25176 Cluster: Cytochrome P-450; n=24; Ditrysia|Rep:
           Cytochrome P-450 - Heliothis virescens (Noctuid moth)
           (Owlet moth)
          Length = 532

 Score =  121 bits (292), Expect = 4e-26
 Identities = 98/428 (22%), Positives = 192/428 (44%), Gaps = 43/428 (10%)

Query: 40  IVFLVDADDIE-IILNSHVH-IDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHI 97
           I+ ++D D ++ I +    H +D+ +    F P  G GLL+  G +W++ R  ++P F  
Sbjct: 79  ILVVLDVDTVKRITVKDFEHFVDRRSFTSSFDPIFGRGLLLLHGDEWKAMRSTMSPAFTS 138

Query: 98  NILKSFVGIFNQNSNNVVEKLKSEV---GKTF---DVHDYMSGTTVDILLETAMGISRKT 151
           + ++  V    + +  ++  L+ ++   GK +   +    M+    D++   A G+   +
Sbjct: 139 SKMRLMVPFMEEIALEMIRVLRGKIKDSGKPYIDVEAKSMMTRYANDVIASCAFGLKVNS 198

Query: 152 Q--DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVI 209
           Q  D   +  + A+ K         +KF       F    FF+    L  +   L   ++
Sbjct: 199 QASDHEFYVNSQAITK---------FKF-----SAFLKVLFFRC---LPSVAQKLKMSLV 241

Query: 210 KNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGE 269
             +   Y  N    ++  T+++      +++ N+   +   V KG       ++++D   
Sbjct: 242 PRECSDYFSN----VVLTTMKD--REKNKVVRNDLINILMEVKKGQLT----HEKDDADA 291

Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329
               A ++      +    + +D ++  +    +F G DT +   SF+L  L ++ DVQ 
Sbjct: 292 DAGFATVEESHIGRKQHNYEWTDSDLIAQAALFLFAGFDTVSTSMSFLLYELAVNPDVQD 351

Query: 330 RVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI----- 384
           R+  E+ +    +     +     M YL+ V+ E LRL+PP  V+ R   +D  I     
Sbjct: 352 RLLQEIREYDEKNHGKIDYNVVQSMTYLDMVVSEGLRLWPPAAVVDRVCVKDYNIGRPNK 411

Query: 385 -STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443
            +TK+ +I  G  V I  ++ HR PK++ +P  F+P+ F PEN      ++Y  F  GPR
Sbjct: 412 KATKDLIIHTGQAVAISPWLFHRNPKFFPEPAKFDPERFSPENRHKILPFTYFSFCLGPR 471

Query: 444 SCVGRKYA 451
           +C+G ++A
Sbjct: 472 NCIGSRFA 479


>UniRef50_A7HP72 Cluster: Cytochrome P450; n=1; Parvibaculum
           lavamentivorans DS-1|Rep: Cytochrome P450 - Parvibaculum
           lavamentivorans DS-1
          Length = 470

 Score =  121 bits (291), Expect = 5e-26
 Identities = 72/222 (32%), Positives = 112/222 (50%), Gaps = 5/222 (2%)

Query: 278 LMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ 337
           LM+  S+ G     D ++++EV T +  GH+TTA   S+V  LL +H + Q R+Y+E++ 
Sbjct: 251 LMVSQSKAGHEMTLD-QVRDEVATFLLAGHETTATTMSWVWYLLTVHPEWQERLYEEVWA 309

Query: 338 IFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTV 397
           +     R  T  D   +     VI E+LRLYPPV  + R+  +  T  T +  I  G TV
Sbjct: 310 V--TEGRRLTIDDVPALVETRAVIEEALRLYPPVANLMRRAIK-TTELTPDITIERGQTV 366

Query: 398 VIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXX 457
           +I  ++LHR   ++++P+ F+P  FL E    R  + YIPF  GPR C+G  +A      
Sbjct: 367 LISPWLLHRHRFFWREPDRFDPTRFLGEEAATRPRHLYIPFGGGPRICIGASFALLEAVL 426

Query: 458 XXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
                 +  R +  I   +   Q  I+L+     Q  V PR+
Sbjct: 427 ILATFMQRAR-VKVINADQVMPQARIVLRPNVALQAVVTPRR 467



 Score = 48.8 bits (111), Expect = 3e-04
 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 3/103 (2%)

Query: 45  DADDIEIILNSHV-HIDKA-TEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKS 102
           D D I  IL S   H  K   +    KP LG GLL + G  WR +RK+ AP F  + ++ 
Sbjct: 74  DPDAIRRILVSDAEHFPKDDNQLAILKPLLGNGLLTAEGATWRRNRKLAAPIFQHSSVRD 133

Query: 103 FVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 145
           F  +F + +     +   + G  F +   M+  T++I+ ET +
Sbjct: 134 FAPLFVRAAERSARRALEQQG-FFPLDREMTKLTLEIIGETVL 175


>UniRef50_UPI0000E48D2E Cluster: PREDICTED: similar to MGC64404
           protein; n=2; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC64404 protein -
           Strongylocentrotus purpuratus
          Length = 509

 Score =  120 bits (290), Expect = 7e-26
 Identities = 60/174 (34%), Positives = 100/174 (57%), Gaps = 3/174 (1%)

Query: 278 LMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ 337
           L  E       KI   ++ +E  T    G +TT+   +F L  +G H+DV  R+ DE+ +
Sbjct: 292 LQAEDDVGNGEKIETADLIDEFGTFFVAGQETTSNLLAFTLLEIGRHKDVAKRLKDEVDE 351

Query: 338 IFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTV 397
           + G S      +D  +++Y+ RV  E++RL PPV   +R+L  DV   +  YVIP G +V
Sbjct: 352 VLG-SKSIIEHSDLTKLEYMSRVFKETMRLNPPVSGASRELASDV--QSCGYVIPKGASV 408

Query: 398 VIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           +  +++  R  +Y+ DP +FNPD F+P +   RH+++Y PF+ G R+C+G++ A
Sbjct: 409 LFLSYLTSRLEEYFDDPLLFNPDRFIPTDETPRHFFAYFPFAIGQRNCIGQQLA 462


>UniRef50_Q1IM54 Cluster: Cytochrome P450; n=1; Acidobacteria
           bacterium Ellin345|Rep: Cytochrome P450 - Acidobacteria
           bacterium (strain Ellin345)
          Length = 460

 Score =  120 bits (290), Expect = 7e-26
 Identities = 66/223 (29%), Positives = 117/223 (52%), Gaps = 5/223 (2%)

Query: 276 LDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDEL 335
           L +MI++  +        +++++V TI   G++TTA   S+   LLG + +V+ RV  E+
Sbjct: 242 LSMMIQAIPDVETPEGKEQLRDQVVTIFLAGYETTANALSWTFRLLGENPEVERRVLAEV 301

Query: 336 YQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGT 395
             +   + R A+  D  ++KY+E V+ ES+RLYPP   + R+   D  +   +Y +P GT
Sbjct: 302 DDVL--NGRMASVEDVPQLKYIEMVLAESMRLYPPAWAMVRQGINDFQLG--DYFLPGGT 357

Query: 396 TVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXX 455
           TV++  +++HR  +++ DP  F+P+ F PE    R  ++Y PF  G R C+G  +A    
Sbjct: 358 TVMMSQWVMHRSEEFWLDPLRFDPERFRPEAKAGRPKFAYFPFGGGGRQCIGEAFAWMEG 417

Query: 456 XXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
                   + +R    +  + F+ Q  I L+   G ++  E R
Sbjct: 418 ALLLATLVQKYR-FRLVAGQTFEPQSLITLRPRNGVRVVAEAR 459



 Score = 46.8 bits (106), Expect = 0.001
 Identities = 28/105 (26%), Positives = 54/105 (51%), Gaps = 5/105 (4%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDI-EIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWR 85
           +G V    +G+K +VFL DA+ I E+++  + +  K    R  K  LG G++ +    WR
Sbjct: 50  YGKVGGYRVGNKRVVFLADAELIREVLVVQNDNFVKGEPVRRTKVLLGNGMITAEQQDWR 109

Query: 86  SHRKMIAPTFHINILKSF----VGIFNQNSNNVVEKLKSEVGKTF 126
           S R+   P FH   ++S+    VG+  +  + +   ++ ++ + F
Sbjct: 110 SQRQAAQPAFHRQRIRSYADQMVGLTIETRDRIAPGIEFDLAQMF 154


>UniRef50_A5P357 Cluster: Cytochrome P450; n=1; Methylobacterium sp.
           4-46|Rep: Cytochrome P450 - Methylobacterium sp. 4-46
          Length = 463

 Score =  120 bits (290), Expect = 7e-26
 Identities = 70/232 (30%), Positives = 116/232 (50%), Gaps = 6/232 (2%)

Query: 268 GEKKRLAFLDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326
           G + R   L L++ +    + + + D ++ + + T +  GH+TTA   ++ L LL +H  
Sbjct: 235 GVEGRDDLLSLLVAARDPESGRAMDDRDVADNLLTFVTAGHETTALALAWTLYLLALHPA 294

Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386
           ++ARV  E+  + G         + L   +  + I E++RLYPP PV+ R    +V +  
Sbjct: 295 IEARVVAEVEAVTGGGPLAPHHVEALG--FTRQAIQEAMRLYPPAPVLVRAALEEVDVG- 351

Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446
             + I  GT V +  + +HR    + +P+ F+PD F PE  + R  Y+Y+PF AGPR C+
Sbjct: 352 -GHRIGPGTPVTVPIYAIHRHALLWDEPDRFDPDRFAPEAAKARDRYAYLPFGAGPRICI 410

Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           G  +A            R+ R  +  P     L+  I L+ AEG  M+V PR
Sbjct: 411 GMSFALMEAVAILAVLIRDLR-FALRPGFVPTLKQRITLRPAEGMPMRVAPR 461



 Score = 40.3 bits (90), Expect = 0.12
 Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 3/108 (2%)

Query: 41  VFLVDADDIEIILNSHVHIDKATEY--RFFKPWLGEGLLISSGPKWRSHRKMIAPTFHIN 98
           +F++D   +  +L       + +E   R   P LG+ +L + G +WR  R+  AP F   
Sbjct: 61  LFVMDPGLVRTVLVDRAESFEKSEVLRRSLSPALGDAILTADGARWRWQRRAAAPIFRNE 120

Query: 99  ILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTVDILLETAM 145
            +  F+      +    E LK    G   D+   M  TT DI+  T +
Sbjct: 121 RILGFLPAMIAAAERTREALKGLPPGTEADLAQVMMRTTFDIIAATML 168


>UniRef50_Q964T2 Cluster: Cytochrome P450 9e2; n=2; Blattaria|Rep:
           Cytochrome P450 9e2 - Blattella germanica (German
           cockroach)
          Length = 533

 Score =  120 bits (290), Expect = 7e-26
 Identities = 59/164 (35%), Positives = 91/164 (55%), Gaps = 1/164 (0%)

Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATF 348
           K  D ++  +     F G DT +    F+  LL  + DVQ R+ DE+ Q   ++D   T+
Sbjct: 318 KWDDDDLTAQAVLFFFAGFDTASTLLCFMSHLLATNPDVQNRLQDEIDQSLEENDGKLTY 377

Query: 349 ADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK-NYVIPAGTTVVIGTFMLHRQ 407
                MKYL+ V+ ESLRLYPP     RK  ++  +  + +Y +  G  V I  + +H  
Sbjct: 378 EAIHSMKYLDMVVSESLRLYPPAIFTDRKCVKNYRLPMEPSYTLEPGDAVWIPIYAIHHD 437

Query: 408 PKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           PKYY +PE F+P+ F  EN  N   ++Y+PF +GPR+C+G ++A
Sbjct: 438 PKYYPNPEKFDPERFSDENKDNIKPFTYLPFGSGPRNCIGNRFA 481


>UniRef50_UPI0000E4657A Cluster: PREDICTED: similar to cytochrome
           P450 3A27; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to cytochrome P450 3A27 -
           Strongylocentrotus purpuratus
          Length = 460

 Score =  120 bits (289), Expect = 9e-26
 Identities = 108/438 (24%), Positives = 188/438 (42%), Gaps = 40/438 (9%)

Query: 72  LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVH 129
           L  G+L +   +WR  R +++P+F    LKS V +  + +  +V+    + E GKT +  
Sbjct: 48  LAGGMLAAKDERWRKLRSLLSPSFTSVKLKSMVPLMRECAEVLVDIFTKREEEGKTIECK 107

Query: 130 DYMSGTTVDILLETAMGI---SRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFK 186
           +      +D++   A G+   S+  QDE    YA  +      +    +   M       
Sbjct: 108 ELYGPYAMDVIGSCAFGLRVNSQTNQDEPFIKYAKRIFNFN--VTNPAFLISMLFPWTAP 165

Query: 187 LTSFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKT 246
           + +FFK     LG        V K+ ++ +L     G+    + +    +G+        
Sbjct: 166 IFNFFK-----LG-------SVPKDIEQFFL-----GVFEKAIAD-RQANGD---TGKSD 204

Query: 247 LSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNK--ISDHEIKEEVDTIMF 304
             + +   +++D D N  ND  +       DL  E+S     K  ++  EI     T + 
Sbjct: 205 FLELMMSAHKEDDDVNIMNDAEDD----IADLAQETSWKPKQKTALNRQEIIGNSITFLL 260

Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364
            G++T++    FV  LL  +Q VQ  +  E+ ++   S    TF    +M+YL  VI+E+
Sbjct: 261 AGYETSSTALGFVSYLLATNQHVQDLLVAEVKEM-APSQSDVTFETVTKMEYLNMVIMEA 319

Query: 365 LRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP 424
           +R+YPP  V+ R  N+++T +  N  I  G  + I  + L      + DPE F+P+ F  
Sbjct: 320 MRIYPPGEVLERVCNKEITYN--NITIKKGQYIFIPIWNLQHDSDLWPDPETFDPERFSK 377

Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEF--KLQGD 482
           +   N H   ++PF  GP +C+G ++A            + FR     PE E   KL   
Sbjct: 378 DRRGNNHPCGWLPFGIGPHTCIGVRFAMLEIKVAMVCILQKFR-FDTCPETEIPPKLGNL 436

Query: 483 IILKRAEGFQMKVEPRKR 500
             L    G  +++ P  R
Sbjct: 437 SFLTPPNGITLRITPHSR 454


>UniRef50_O76345 Cluster: Cytochrome P450; n=1; Homarus
           americanus|Rep: Cytochrome P450 - Homarus americanus
           (American lobster)
          Length = 518

 Score =  120 bits (289), Expect = 9e-26
 Identities = 55/164 (33%), Positives = 96/164 (58%), Gaps = 4/164 (2%)

Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATF 348
           K++D E+ +     +  G +TT+   ++   LL ++ D+Q +++ E+ ++ G  +R  ++
Sbjct: 283 KLTDEEVVDNAFLFLLAGFETTSTALTYTSYLLALNPDIQEKIFQEVEEVVG-LERAPSY 341

Query: 349 ADTLEMKYLERVILESLRLYPPVP-VIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ 407
            D  ++ Y E V LES R+YPPV   I R+  +D       Y IPAGT V +  + +H  
Sbjct: 342 EDLSKLVYTEAVALESTRMYPPVTGFITRQATQDWQYGP--YTIPAGTEVEVPVWSIHHN 399

Query: 408 PKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           P+ Y  PE+F P+ FLP+  ++RH  +Y+ F  GPR+C+G ++A
Sbjct: 400 PELYPQPELFKPERFLPKAKKDRHTMAYLGFGGGPRNCLGLRFA 443


>UniRef50_UPI00015B5073 Cluster: PREDICTED: similar to cytochrome
           P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 1350

 Score =  120 bits (288), Expect = 1e-25
 Identities = 62/174 (35%), Positives = 94/174 (54%), Gaps = 7/174 (4%)

Query: 282 SSQNGTNKISDHE---IKEEVDTIMF---EGHDTTAAGSSFVLCLLGIHQDVQARVYDEL 335
           S  N   KI+D +   + E V   MF    G +TTA+  ++ L  L  +QD+Q  +Y+E+
Sbjct: 225 SKSNSLTKITDADKITMVEAVGQSMFFFAAGQETTASAITYCLYELSFNQDIQEELYNEI 284

Query: 336 YQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGT 395
            Q+   S    T+     M YL+ V  E+LR +P  P++ R+ + D  +   ++VI  GT
Sbjct: 285 SQV-AHSPEGLTYEKLFSMPYLDMVFRETLRKHPGAPMLNRQASEDFVVPGSHFVIKKGT 343

Query: 396 TVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 449
            +VI    LH  P  Y DP+ F+P  F  EN   RH ++YIPF  GPR C+G++
Sbjct: 344 RIVIPIKALHADPDIYPDPDKFDPTRFTSENKAKRHAFTYIPFGEGPRHCIGKR 397



 Score = 39.5 bits (88), Expect = 0.20
 Identities = 38/181 (20%), Positives = 83/181 (45%), Gaps = 11/181 (6%)

Query: 41  VFLVDADDIEIILNSHVH--IDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHIN 98
           +FL+D + I++IL  H +   ++ T Y   K  L  GL+     KW+  R  ++PTF   
Sbjct: 20  LFLMDPELIQLILVKHFNSFYNRGTLYNESKDPLSTGLVRLYDEKWKRLRVKLSPTFTSG 79

Query: 99  ILKSFVGIFNQNSNNVVEKLKSEVGKT--FDVHDYMSGTTVDILLETAMGISRKTQDESG 156
            LK    +  +  + ++   +  + K+   ++ D  +  T+D +   A G +  +  +  
Sbjct: 80  KLKLMYPLVKEICDELLRVYEDVLDKSDVVEIKDITNRFTIDCISSIAFGFNCDSLHQPD 139

Query: 157 FDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFF---KQQTKLLGIIHGLTNKVIKNKK 213
            ++    +K   I +     F + S  V +L S F   +++ K+    + L  K++ +++
Sbjct: 140 NEF----LKYGKISNDLGRVFLIFSFFVPRLVSLFPIPEKRKKVSEFFYDLFEKMVSHRR 195

Query: 214 E 214
           +
Sbjct: 196 K 196


>UniRef50_Q9VYQ7 Cluster: Probable cytochrome P450 311a1; n=2;
           Drosophila melanogaster|Rep: Probable cytochrome P450
           311a1 - Drosophila melanogaster (Fruit fly)
          Length = 483

 Score =  120 bits (288), Expect = 1e-25
 Identities = 77/232 (33%), Positives = 114/232 (49%), Gaps = 10/232 (4%)

Query: 266 DVGEKKRLA--FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323
           D+GE    A   LD ++ +   G + +S  EI++E++T +F G DTT A  SFVL  L  
Sbjct: 253 DMGEPAGRAHNLLDTLLLAKFEGQS-LSRREIRDEINTFVFAGVDTTTAAMSFVLYALAK 311

Query: 324 HQDVQARVYDELYQIFGDSDRPATFADTLE-MKYLERVILESLRLYPPVPVIARKLNRDV 382
             + Q R+  EL  +  D     T  D L  + YLE +I E LRLY  VP   R+  +  
Sbjct: 312 FPETQTRLRKELQDVALDE---TTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQST 368

Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPEN-TQNRHYYSYIPFSAG 441
            I  + Y   AG T+ I  + L    +YY DP  F P+ +LPE+       +SYIPFS G
Sbjct: 369 EIGGRTYC--AGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGG 426

Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQM 493
           P  C+GR+Y+            R F+      +   +L+  ++LK  +G  +
Sbjct: 427 PHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINV 478



 Score = 80.6 bits (190), Expect = 9e-14
 Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 1/192 (0%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86
           FG   R+ LG +L VFL  A++    L+    + KA  +   +P +G GLLIS G  W  
Sbjct: 63  FGATYRLRLGPQLWVFLHSAEETRQALHDPT-LRKADTFMQLEPLIGNGLLISHGAHWTR 121

Query: 87  HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMG 146
            R+++ P F   +L+SF      +   +V +L +  G   +V + +    +D +++T+MG
Sbjct: 122 QRRLLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVTEPLFACLLDAIVDTSMG 181

Query: 147 ISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTN 206
               TQ         A      ++ +R     + S+ +F+ T  ++   + L +IH    
Sbjct: 182 AQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQME 241

Query: 207 KVIKNKKETYLE 218
            VI+ + +  L+
Sbjct: 242 SVIEKRAKELLD 253


>UniRef50_UPI0000D576F7 Cluster: PREDICTED: similar to Cytochrome
           P450 6a8 (CYPVIA8); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 6a8 (CYPVIA8) -
           Tribolium castaneum
          Length = 491

 Score =  119 bits (287), Expect = 2e-25
 Identities = 66/226 (29%), Positives = 112/226 (49%), Gaps = 5/226 (2%)

Query: 257 DDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISD-HEIKEEVDTIMFEGHDTTAAGSS 315
           D + F +EN+     R  F+  +I+       ++    E+  +       G +T+ A  S
Sbjct: 250 DIIKFREENNY---TRDDFMQFLIKLKNKSAKQVFTLEEVASQCVLFFIAGFETSHATMS 306

Query: 316 FVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIA 375
           F L  L  HQD+Q +V +E + +    +   T+    ++KYL++V+ E+LR YP V  + 
Sbjct: 307 FALYELAKHQDIQQKVREEFWAVVDSQESEITYEAVQKLKYLDQVLNETLRKYPVVMYLT 366

Query: 376 RKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSY 435
           R+  +D  +     VI  GTTV+I T  L+    YY +P+ F+P  F  EN + RH   +
Sbjct: 367 RRCIKDYKVPEDGAVIEKGTTVIIPTVALNYDENYYPNPKKFDPQRFSEENKKLRHPCIH 426

Query: 436 IPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQ 480
           +PF  GPR C+GR++A            +N+  T++    +  KL+
Sbjct: 427 LPFGLGPRFCIGRRFALIQVKVGLVLLLKNYSFTVNPNTREPIKLK 472


>UniRef50_Q825N1 Cluster: Cytochrome P450 hydroxylase; n=6;
           Actinomycetales|Rep: Cytochrome P450 hydroxylase -
           Streptomyces avermitilis
          Length = 504

 Score =  119 bits (287), Expect = 2e-25
 Identities = 71/229 (31%), Positives = 125/229 (54%), Gaps = 8/229 (3%)

Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           LD M+++++ GT  +++   I+ +V T +  GH+TT+   SF L  L  H DV AR   E
Sbjct: 257 LDRMLDTARPGTGERLAPENIRRQVITFLVAGHETTSGALSFALHYLSRHPDVAARARAE 316

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           + +++G + RP  +    +++Y+ RV+ ESLRL+P  P  AR+  RD T+    + +  G
Sbjct: 317 VDRVWGGTARPG-YDQVAKLRYVRRVLDESLRLWPTAPAFAREARRD-TVLGGVHPMREG 374

Query: 395 TTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXX 453
              ++ T MLHR P  +  D E F+PD F  +  ++R  +++ PF  G R+C+GR++A  
Sbjct: 375 AWALVLTAMLHRDPGVWGADAERFDPDRFDAQAVRSRAAHTFKPFGTGARACIGRQFALH 434

Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRVP 502
                     R +   +E P    ++   + L   EG +++++  +RVP
Sbjct: 435 EATLVLGLLLRRYELRAE-PGYRLRVAERLTL-MPEGLRLRLD--RRVP 479


>UniRef50_A4X8D8 Cluster: Cytochrome P450; n=5; Actinomycetales|Rep:
           Cytochrome P450 - Salinispora tropica CNB-440
          Length = 452

 Score =  119 bits (287), Expect = 2e-25
 Identities = 65/208 (31%), Positives = 109/208 (52%), Gaps = 5/208 (2%)

Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349
           ++   +++E+ T++  GH+TTA+   +   L+     V+ R+ +E   + G   R   +A
Sbjct: 248 VARRRMRDELVTLLLAGHETTASTLGWTFHLINQDPRVRVRLREEAIDVLGG--RLPEYA 305

Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409
           D   + Y + V+ E++RLYPPV +++R L RD  +    Y +PA   V+I  + LHR P 
Sbjct: 306 DLARLTYTKMVVSEAMRLYPPVWMLSR-LARDADV-VDGYPVPARADVLICPYTLHRHPA 363

Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTI 469
           ++ +PE F+P+ F PE T +R  Y+Y+PF AGPR CVG                R F  +
Sbjct: 364 FWPEPERFDPERFDPEVTTDRPRYAYVPFGAGPRFCVGNHLGLMEAVFVVAMVSREFDLV 423

Query: 470 SEIPEKEFKLQGDIILKRAEGFQMKVEP 497
           + + +     +  + L+   G  M VEP
Sbjct: 424 APVGQ-PVVAEPMLSLRVRGGLSMTVEP 450



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 28/124 (22%), Positives = 60/124 (48%), Gaps = 2/124 (1%)

Query: 24  AQTFGNVIRVWLGSKLIVFLVDADDIEIIL-NSHVHIDKATEYRFFKPWLGEGLLISSGP 82
           A  +G+ +R+ +GS+ + F    D  + +L ++  +  K       +  LG+GLL S G 
Sbjct: 36  AARYGDAVRLGVGSRSLYFFNHPDHAKHVLADNSGNYTKGLGLVHARRALGDGLLTSEGE 95

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDILL 141
            WR  R++I P F    +        + ++ ++ +L++  G+   ++ D  +  T+ +L 
Sbjct: 96  LWREQRRVIQPVFQAKRVAGQAHAVAEEADRLIARLRARRGRGPVNLTDEFTALTLGVLG 155

Query: 142 ETAM 145
            T +
Sbjct: 156 RTLL 159


>UniRef50_A1UDQ6 Cluster: Cytochrome P450; n=10; Mycobacterium|Rep:
           Cytochrome P450 - Mycobacterium sp. (strain KMS)
          Length = 474

 Score =  119 bits (287), Expect = 2e-25
 Identities = 66/174 (37%), Positives = 98/174 (56%), Gaps = 6/174 (3%)

Query: 279 MIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ 337
           +I +S   T + +SD +I  E+   M  GHDTTA   ++ L  LG H D+Q RV  E   
Sbjct: 260 LINASDPETGRSLSDDDICNELLVFMLAGHDTTATLLTYALWALGHHPDIQDRVAAEACA 319

Query: 338 IFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTV 397
           +    DR  T  D   + Y  +V+ ESLRL PP   + R   RDV +    Y + AG+ V
Sbjct: 320 L---GDRLPTPDDVGRLGYTVQVLNESLRLCPPAAGVGRMALRDVEVD--GYRVEAGSLV 374

Query: 398 VIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
            IG + +HR P+ +  P  F+P+ F PEN ++R  + +IPF+ GPR+C+G+ +A
Sbjct: 375 GIGIYAVHRDPELWDRPLEFDPERFSPENVKDRDRWQFIPFAGGPRACIGQHFA 428


>UniRef50_Q8UF31 Cluster: Cytochrome P450; n=1; Agrobacterium
           tumefaciens str. C58|Rep: Cytochrome P450 -
           Agrobacterium tumefaciens (strain C58 / ATCC 33970)
          Length = 464

 Score =  119 bits (286), Expect = 2e-25
 Identities = 58/177 (32%), Positives = 98/177 (55%), Gaps = 5/177 (2%)

Query: 276 LDLMIESSQNGTNKI-SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           + +++E+    T ++ SD EI + + T +  GH+TTA G ++   LL  + + + +  +E
Sbjct: 239 VSMLLEAKDPETGRMMSDEEIIDNLLTFITAGHETTALGLAWTFHLLSQNPETERKAVEE 298

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           +  + G    P        + Y+ +V  E++RLYPP PVI R   +D  +   +  IPAG
Sbjct: 299 IEAVTGGE--PVAAEHIANLAYVRQVFSEAMRLYPPAPVITRTALQDFRLGEHD--IPAG 354

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           T + +  + +HR    + +PE F+P  F PE  + RH Y+Y+PF AGPR C+G  +A
Sbjct: 355 TVLYVPIYAVHRHTALWDEPERFDPSRFEPEKVKARHRYAYMPFGAGPRVCIGNAFA 411



 Score = 46.4 bits (105), Expect = 0.002
 Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 6/131 (4%)

Query: 35  LGSKLIVFLVDADDI-EIILNSHVHIDKATEYR-FFKPWLGEGLLISSGPKWRSHRKMIA 92
           LG  + V L D   I E ++ +   + K  + R    P LG+GLL + G  W+  R+ +A
Sbjct: 53  LGGVMRVHLADPVLIHEALVKNAALLGKGEDVRRALGPALGQGLLTADGDHWKWQRQSVA 112

Query: 93  PTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM----GIS 148
             F    L   + +  + +    ++ +S      D+   M  TT DI++ET M    GI 
Sbjct: 113 AAFRHEKLLELLPVMIETARRTQKRWRSSSTADIDIGHEMMRTTFDIIVETMMSGGYGID 172

Query: 149 RKTQDESGFDY 159
               ++S  DY
Sbjct: 173 IARVEQSITDY 183


>UniRef50_Q89R90 Cluster: Blr2882 protein; n=4; Bacteria|Rep:
           Blr2882 protein - Bradyrhizobium japonicum
          Length = 1078

 Score =  119 bits (286), Expect = 2e-25
 Identities = 64/212 (30%), Positives = 109/212 (51%), Gaps = 4/212 (1%)

Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG-DSDRPAT 347
           ++ D  I+ +++T +  GH+TT+   S+ L  L  H D+  + YDE+ ++FG D +   T
Sbjct: 255 QLDDVNIRYQINTFLIAGHETTSGLLSYTLYALLKHPDILKKAYDEVDRVFGPDVNAKPT 314

Query: 348 FADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ 407
           +    ++ Y+ +++ E+LRL+PP P        D TI    Y +  GT + I    LHR 
Sbjct: 315 YQQVTQLTYITQILKEALRLWPPAPAYGISPLADETIGGGKYKLRKGTFITILVTALHRD 374

Query: 408 PKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF 466
           P  +  +P+ F+P+NF  E    R   ++ PF  G R+C+GR +A            + F
Sbjct: 375 PSVWGPNPDAFDPENFSREAEAKRPINAWKPFGNGQRACIGRGFAMHEAALALGMILQRF 434

Query: 467 RTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           + I      +  L+  + +K  EGF++KV PR
Sbjct: 435 KLIDH-QRYQMHLKETLTMK-PEGFKIKVRPR 464


>UniRef50_UPI0000D56428 Cluster: PREDICTED: similar to Cytochrome
           P450 4g1 (CYPIVG1); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1) -
           Tribolium castaneum
          Length = 713

 Score =  118 bits (285), Expect = 3e-25
 Identities = 62/174 (35%), Positives = 97/174 (55%), Gaps = 7/174 (4%)

Query: 297 EEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKY 356
           EE   + F G +T+    S VL +LG+   +Q +++ E+ Q+FG S   +T  +   + Y
Sbjct: 269 EEAQIMFFVGTETSGVAISSVLLILGMFPQIQEKIFIEIDQVFG-STTGSTLDEINHLDY 327

Query: 357 LERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEV 416
           LERVI E+LRL PP+P + R L+ ++ +S   +  PAG+ V++   M+HR+  ++ +P  
Sbjct: 328 LERVIKETLRLLPPIPFVMRSLDENLKLSCGTF--PAGSRVIVPIMMVHRREDFWPEPLK 385

Query: 417 FNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTIS 470
           F+PD FL E        +YIPFS G R+C+G KYA            R +R  S
Sbjct: 386 FDPDRFLEERPSG----TYIPFSYGTRNCLGYKYAMLSMKVILATILRKYRVKS 435



 Score = 63.3 bits (147), Expect = 1e-08
 Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 3/119 (2%)

Query: 25  QTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKW 84
           +++  V+++W G  L V   +  D+++IL +H H+DK   Y     +    L  +    W
Sbjct: 61  KSYPKVVKIWFGPWLYVSTTEPSDLKVIL-TH-HLDKGEFYELMSEYFRRALAAAPVDLW 118

Query: 85  RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLET 143
           + HRK I PTF+  IL +F+G F + +  +V+ L+ +     D+   +   T+D   ET
Sbjct: 119 KKHRKNINPTFNTTILNTFIGAFAKQAEILVKNLE-KYQSDEDIFPIVWKCTLDSACET 176


>UniRef50_O76107 Cluster: Cytochrome P450; n=2; Culicini|Rep:
           Cytochrome P450 - Culex quinquefasciatus (Southern house
           mosquito)
          Length = 499

 Score =  118 bits (285), Expect = 3e-25
 Identities = 70/242 (28%), Positives = 123/242 (50%), Gaps = 14/242 (5%)

Query: 228 TLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGT 287
           T  +F++  G  +  N   +SD      RD + F  +N    K    F+DL+I+   N T
Sbjct: 223 TYRKFSNQIGICVLPN--DVSDFYLGAVRDTIKFRMDNQASRKD---FMDLLIKLEDNFT 277

Query: 288 NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPAT 347
                +EI  +       G++T++   +F L  L ++Q++Q R    +  +     R  +
Sbjct: 278 F----NEIAAQAFVFFQAGYETSSITMTFCLYELALNQELQERARKSVEDVL---KRHGS 330

Query: 348 FA-DTLE-MKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLH 405
           F+ +T++ M++L   + E+LR YPPV  + R++ ++  +   +  +  G  VVI  + +H
Sbjct: 331 FSYETIQDMEFLNCCVKETLRKYPPVANLFREITKNYKVPETDITLEKGYRVVIPVYGIH 390

Query: 406 RQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRN 465
             P  Y +PEVFNP+ F+PE + NRH  +Y+PF  GPR+C+G ++A            + 
Sbjct: 391 HDPDIYPNPEVFNPERFIPELSTNRHPMAYLPFGEGPRTCIGERFALMETKIGLSRLLQK 450

Query: 466 FR 467
           FR
Sbjct: 451 FR 452



 Score = 38.7 bits (86), Expect = 0.36
 Identities = 30/138 (21%), Positives = 57/138 (41%), Gaps = 3/138 (2%)

Query: 12  LTQKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPW 71
           + Q L     G    FG +        +++ L  A D+ +    + H D+   Y      
Sbjct: 52  IMQDLYGKLKGSGAKFGGIYSFLKPMVMVLDLDFAKDVLVREFQYFH-DRGMYYNERDDP 110

Query: 72  LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNV--VEKLKSEVGKTFDVH 129
           L   L+   G KW+S R  + PTF    +K   G   +  + +    +++ E G+  ++ 
Sbjct: 111 LSAHLVSLEGDKWKSLRTKLTPTFTSGKMKMMFGTIEEVVDRLEGCIRVRVESGECIEIR 170

Query: 130 DYMSGTTVDILLETAMGI 147
           D +S   +D++   A G+
Sbjct: 171 DIISRFAMDVIGSCAFGL 188


>UniRef50_A7SXR0 Cluster: Predicted protein; n=5; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 481

 Score =  118 bits (285), Expect = 3e-25
 Identities = 65/185 (35%), Positives = 102/185 (55%), Gaps = 3/185 (1%)

Query: 268 GEKKRLAFLDLMI-ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326
           G KK L  L L   E + +G  +++D E+  +  T +  G +TT    +    LL  H D
Sbjct: 251 GRKKDLVTLMLEAREDTVDGVPRLNDQELAAQSLTFLLAGFETTTNTLANTAYLLARHPD 310

Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386
           VQ ++  EL     +      +  + ++ YL+RVI ESLRLYPP  +I R+ + + TI  
Sbjct: 311 VQDKLIQELDLAGSNRGNSPLYEYSQKIDYLDRVINESLRLYPPGYLIIRRYDEECTIQG 370

Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446
            ++  P G  V I  ++LHR P  ++ P+ F+P++F  E  + RH YS+IPF  GPR C+
Sbjct: 371 VHF--PRGVDVNIPVYILHRDPAVWERPDDFDPEHFSHEANEKRHPYSFIPFGMGPRQCI 428

Query: 447 GRKYA 451
           G ++A
Sbjct: 429 GMRFA 433



 Score = 38.3 bits (85), Expect = 0.47
 Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 7/172 (4%)

Query: 19  LALGYAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPW--LGEGL 76
           + + Y + +G V ++++G    + + D + ++ I+    H        F KP   +  G+
Sbjct: 54  MLMHYFKAYGRVHKMFIGRAPAIVVSDPEIVKQIVIKEFH-KFPNRPLFIKPNPPMDSGM 112

Query: 77  LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 136
            +  G  W+  R  + PTF    LK  V I +     +  + + E  ++ D  +  S   
Sbjct: 113 FLGQGALWKRIRTTLTPTFSTAKLKQIVPIIDSRKWPLSPQ-QVERSESTDCVNLFSLFA 171

Query: 137 VDILLETAMGISR--KTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFK 186
           +D++  +A G+    +T  +S F Y +A       I  R +  +  SE + K
Sbjct: 172 LDVITISAFGVETDIQTDPDSSF-YKLAKKAFRTPIWVRAFSMFPFSEYLSK 222


>UniRef50_UPI0000F21E21 Cluster: PREDICTED: similar to cytochrome
           P450 CYP4F13; n=1; Danio rerio|Rep: PREDICTED: similar
           to cytochrome P450 CYP4F13 - Danio rerio
          Length = 328

 Score =  118 bits (284), Expect = 4e-25
 Identities = 59/163 (36%), Positives = 96/163 (58%), Gaps = 2/163 (1%)

Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPAT-F 348
           +++ EIK   D  MF GHDTTA+  S++   L ++QD Q R   E+  +  D D     +
Sbjct: 119 LTNEEIKAHADMFMFAGHDTTASALSWIFYNLAMNQDYQERCRAEVRDLLADRDTHTIGW 178

Query: 349 ADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQP 408
            D  ++ +    I ESLRL+ PV  + R  ++++  +  + VIP G   +I  + +HR P
Sbjct: 179 EDLSQLTFTTMCIKESLRLHSPVLALTRYYSQNMK-TPGDCVIPHGCLCLISIYGVHRNP 237

Query: 409 KYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           + + DP VF+P  F P N+ +R  +++IPFSAGPR+C+G+ +A
Sbjct: 238 QVWPDPLVFDPTRFDPHNSDSRSPHAFIPFSAGPRNCIGQNFA 280



 Score = 67.7 bits (158), Expect = 7e-10
 Identities = 26/48 (54%), Positives = 35/48 (72%)

Query: 65  YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSN 112
           Y F KPWLG  LL+ SG +W  HR+++ P FH +ILK +V IFNQ++N
Sbjct: 62  YGFMKPWLGNCLLLQSGQEWSRHRRLLTPAFHFDILKKYVHIFNQSTN 109


>UniRef50_Q1DEH2 Cluster: Cytochrome P450 family protein; n=1;
           Myxococcus xanthus DK 1622|Rep: Cytochrome P450 family
           protein - Myxococcus xanthus (strain DK 1622)
          Length = 467

 Score =  118 bits (284), Expect = 4e-25
 Identities = 58/178 (32%), Positives = 94/178 (52%), Gaps = 4/178 (2%)

Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349
           +S++++++E+ T++  GH+TTA    +   LL  H + +AR+  EL  + G   R     
Sbjct: 250 LSENQLRDELATMIMSGHETTADALVWAWYLLAQHPEAEARLVAELETVLGG--RLPGAE 307

Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409
           D   ++Y E V+ E++RLY P  + +R+  RD  +    + +PAGT + +  ++ HR  +
Sbjct: 308 DLPRLRYTEAVVKEAMRLYSPAWITSREALRDCELG--GFHVPAGTMLAVSQWVTHRDAR 365

Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467
           Y+  PE F PD +L E+ Q  H Y Y PF  GPR C+G   A            R FR
Sbjct: 366 YFDAPESFRPDRWLSEDAQRMHRYVYFPFGGGPRFCIGSALAMMETVLITACVARRFR 423


>UniRef50_Q9V4T3 Cluster: Probable cytochrome P450 4ad1; n=2;
           Sophophora|Rep: Probable cytochrome P450 4ad1 -
           Drosophila melanogaster (Fruit fly)
          Length = 516

 Score =  118 bits (284), Expect = 4e-25
 Identities = 71/207 (34%), Positives = 104/207 (50%), Gaps = 5/207 (2%)

Query: 268 GEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327
           G+     FLD+++ +  +G   + + EI EEV T +F GHD  AA  SF L  L  H ++
Sbjct: 269 GQPINKPFLDVLLTAKLDG-KVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEI 327

Query: 328 QARVYDELYQIFGDS-DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386
           Q +  +E  +IFG++    A  A   +M YLE +I E+LRLYP VP+IAR  NR+  I  
Sbjct: 328 QQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIAR-TNRN-PIDI 385

Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNF-LPENTQNRHYYSYIPFSAGPRSC 445
               +   TTV++    +    KY+ DP  F P+ F  P        +  +PFSAGPR C
Sbjct: 386 NGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRRC 445

Query: 446 VGRKYAXXXXXXXXXXXXRNFRTISEI 472
           +  K+A            R F  +  +
Sbjct: 446 IAEKFAMYQMKALLSQLLRRFEILPAV 472



 Score =  110 bits (264), Expect = 1e-22
 Identities = 51/175 (29%), Positives = 98/175 (56%), Gaps = 2/175 (1%)

Query: 41  VFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINIL 100
           + L D  +I+ IL+S   + K   Y F +PWLG+GLL SSG +W  H+K+ AP F  + +
Sbjct: 83  MMLSDPAEIQNILSSSSLLYKEHLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSAI 142

Query: 101 KSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFD 158
           + ++ + ++     V+KL   S+  + FD  + ++  T+DI+ E A G    + +    D
Sbjct: 143 EGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGETSD 202

Query: 159 YAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213
              A+  +CD++ +R +    R + +F+LTS++ +Q + L ++    N++I  ++
Sbjct: 203 LHGAIKDLCDVVQERTFSIVKRFDALFRLTSYYMKQRRALSLLRSELNRIISQRR 257


>UniRef50_Q9PWP0 Cluster: Cytochrome P450; n=2; Dicentrarchus
           labrax|Rep: Cytochrome P450 - Dicentrarchus labrax
           (European sea bass)
          Length = 526

 Score =  118 bits (283), Expect = 5e-25
 Identities = 58/183 (31%), Positives = 99/183 (54%), Gaps = 2/183 (1%)

Query: 270 KKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQA 329
           +K+  F+D+++ S       ++D EI+ E +T MF GHDTTA+   + L  L  H   Q 
Sbjct: 292 QKKKDFVDIILLSRDEDGQGLTDEEIQAEANTFMFAGHDTTASAICWTLYNLARHDQYQE 351

Query: 330 RVYDELYQIFGDSDR-PATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN 388
           +   E+ ++    DR    + D   + +    I ESLRL+ PV  + RK  +D+T+   +
Sbjct: 352 KCRQEVMELMEGRDRHEIEWEDLSNLPFTTMCIRESLRLHSPVQAVTRKYTQDMTLPG-D 410

Query: 389 YVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
             +P G   ++  +  H  P  + +P  F+P  F P N +    +++IPFS+GPR+C+G+
Sbjct: 411 CTVPKGAICLVSIYGTHHNPTVWTNPHEFHPLRFDPTNKEGLAAHAFIPFSSGPRNCIGQ 470

Query: 449 KYA 451
           K+A
Sbjct: 471 KFA 473



 Score = 95.1 bits (226), Expect = 4e-18
 Identities = 53/179 (29%), Positives = 100/179 (55%), Gaps = 6/179 (3%)

Query: 40  IVFLVDADDIEIILNSHVHIDKATE--YRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHI 97
           +V L   D ++ +L +   I    E  Y   +PWLG+ LL+S+G +W   R+++ P FH 
Sbjct: 100 LVRLFHPDYVKPLLMAPASITVKDELIYGHLRPWLGQSLLLSNGEEWSRKRRLLTPAFHF 159

Query: 98  NILKSFVGIFNQNSNNVVEKLKSE--VGKT-FDVHDYMSGTTVDILLETAMGISRKTQDE 154
           +IL+++V IFN ++N + +K +    VG T  ++ D+++  T+D LL+ A   +   Q +
Sbjct: 160 DILRNYVAIFNTSTNTMHDKWRHHLAVGTTNLEMFDHITLMTLDSLLKCAFSYNSNCQ-Q 218

Query: 155 SGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNKK 213
           S  +Y  A++++ D+I  R  K     + ++  T   K+  K L I+H  T +V++ ++
Sbjct: 219 STSEYVSAIVELSDLIIDRRQKILHHWDWIYWKTKQGKRFKKALSIVHRFTREVVQKRR 277


>UniRef50_A1WAC7 Cluster: Cytochrome P450; n=1; Acidovorax sp.
           JS42|Rep: Cytochrome P450 - Acidovorax sp. (strain JS42)
          Length = 437

 Score =  118 bits (283), Expect = 5e-25
 Identities = 65/211 (30%), Positives = 112/211 (53%), Gaps = 8/211 (3%)

Query: 275 FLDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYD 333
           +L +++++    + + + D  + +EV T++  GH+TTA+  ++   LL  H + +A ++ 
Sbjct: 213 WLSMLMQARDKASGEPMPDRALLDEVMTLIVAGHETTASTLNWTWYLLARHPEAEAALHA 272

Query: 334 ELYQIFGDSDRP--ATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVI 391
            +         P  A         Y+E+V+ E+LRLYPPV + +R+  +D T+    Y +
Sbjct: 273 AIANAAPTEAAPDQALATPFASADYVEQVLQEALRLYPPVWLFSRRAVQDDTLG--GYHV 330

Query: 392 PAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           PAGT + I  ++LHR    ++ PE F P  F+P+    RH ++Y+PFSAGPR CVG  +A
Sbjct: 331 PAGTDIFICPYLLHRDAAQWERPEEFLPARFMPDAAAGRHRFAYLPFSAGPRFCVGAGFA 390

Query: 452 XXXXXXXXXXXXRNFRTI---SEIPEKEFKL 479
                         FR +   +E  E EF++
Sbjct: 391 MAEMATHLTMVAERFRWVPVDAEPAEAEFQI 421



 Score = 43.2 bits (97), Expect = 0.017
 Identities = 28/117 (23%), Positives = 53/117 (45%), Gaps = 5/117 (4%)

Query: 45  DADDIE-IILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSF 103
           D DDI  ++L +  +  K       +  LG GL++S G  W   R+MI P F     + F
Sbjct: 53  DPDDIRRVLLTNRGNYVKGAGLERVRVLLGNGLIVSDGDLWVRQRRMIQPAFQGQATRGF 112

Query: 104 VGIFNQNSNNVVEK--LKSEVGKTFDVHDYMSGTTVDILLET--AMGISRKTQDESG 156
             +  Q + +++ +    ++ G+  D+   +S   ++I+L    +    R  + E G
Sbjct: 113 APVVRQVNADLLTRWSAHADSGEPIDLTHELSSVALEIVLRALFSADFDRLVETEGG 169


>UniRef50_A7LFI0 Cluster: Cytochrome P450; n=3; Tribolium
           castaneum|Rep: Cytochrome P450 - Tribolium castaneum
           (Red flour beetle)
          Length = 493

 Score =  118 bits (283), Expect = 5e-25
 Identities = 66/227 (29%), Positives = 119/227 (52%), Gaps = 9/227 (3%)

Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLM--IESSQNGTNKIS-DHEIKEEVDT 301
           KT SD +   ++  L   ++  +    R  F+DL+  +  ++  T+    D++IK     
Sbjct: 236 KTASDYLINVFKTTLQEREKKKI---IRNDFIDLLSNLRKTETITDSYKFDNDIKMAAQA 292

Query: 302 IMF--EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLER 359
           I F   G+DTT+   +     L +++ +Q R+  E+ +I+ ++    T+ + L MKYL+ 
Sbjct: 293 IAFFSAGNDTTSITLALTCYELSLNKTIQDRLRHEVTEIYNENGE-FTYENILGMKYLDM 351

Query: 360 VILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNP 419
           VI E+LR YP  P + RK +   T     + +  G ++++    LH  P+YY DPE ++P
Sbjct: 352 VISETLRKYPLAPFLNRKSDVKYTFEETGFTLDKGVSIMVPISGLHYDPEYYPDPEKYDP 411

Query: 420 DNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF 466
           + F  EN +N   Y+Y+PF  GPR+C+G+++A            ++F
Sbjct: 412 ERFSDENKKNLTPYTYLPFGEGPRNCIGQRFALLVSKVALASVVKDF 458


>UniRef50_A0NGH0 Cluster: ENSANGP00000031109; n=7; Culicidae|Rep:
           ENSANGP00000031109 - Anopheles gambiae str. PEST
          Length = 541

 Score =  118 bits (283), Expect = 5e-25
 Identities = 64/220 (29%), Positives = 114/220 (51%), Gaps = 8/220 (3%)

Query: 287 TNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD-RP 345
           T + ++ E+  +       G DT +    F++  L  +++VQ R+Y+E+ +I    D +P
Sbjct: 320 TREWTEKELVAQCFLFFLAGFDTVSTALGFLMYELMRNREVQERLYEEIAEIDQRLDGKP 379

Query: 346 ATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN---YVIPAGTTVVIGTF 402
            T+     M+Y++ V+ ESLRL+PP P++ R  NRD T        + I  G TV++   
Sbjct: 380 LTYDAVQGMRYMDMVVSESLRLWPPAPMVDRYCNRDYTFDDGEGLRFKIEKGVTVMVPVA 439

Query: 403 MLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXX 462
            LH  PKY+ DP+ F+P+ F  EN    +  +Y+PF  GPR+C+G ++A           
Sbjct: 440 GLHSDPKYFPDPKRFDPERFSEENRHKINPGAYLPFGVGPRNCIGSRFALMEVKSIIYYL 499

Query: 463 XRNFRTISEIPEKEFKLQ---GDIILKRAEGFQMKVEPRK 499
            ++F T     + +  L+     ++L   +G  ++ +PR+
Sbjct: 500 LKSF-TFERCEQTQVPLRLKNSPVVLAAEKGIWIRFKPRE 538


>UniRef50_UPI000065CBAF Cluster: Thromboxane-A synthase (EC
           5.3.99.5) (TXA synthase) (TXS) (Cytochrome P450 5A1).;
           n=1; Takifugu rubripes|Rep: Thromboxane-A synthase (EC
           5.3.99.5) (TXA synthase) (TXS) (Cytochrome P450 5A1). -
           Takifugu rubripes
          Length = 391

 Score =  117 bits (282), Expect = 6e-25
 Identities = 61/181 (33%), Positives = 98/181 (54%), Gaps = 3/181 (1%)

Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349
           I++ EI  +    +  G++T++   +F   LL I+ + Q  +  E+   F   + P  + 
Sbjct: 205 ITEDEIVGQAFVFLVAGYETSSNTLAFACYLLAINPECQRELQKEVDHFFTRHESP-DYT 263

Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409
           +  E+KYL+ VI E+LRLYPP    AR++ RD  ++ +++  P G T  I    LHR P+
Sbjct: 264 NVQELKYLDMVISETLRLYPPGFRFAREIERDCVVNGQSF--PKGATFEIPAGFLHRDPE 321

Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTI 469
           ++ DP+ F P+ F PE   +RH + YIPF AGPR+CVG + A            R F  +
Sbjct: 322 HWPDPDKFIPERFTPEAKASRHPFVYIPFGAGPRNCVGMRLAQLEMKMALVRLFRRFNLL 381

Query: 470 S 470
           +
Sbjct: 382 A 382



 Score = 40.7 bits (91), Expect = 0.089
 Identities = 25/125 (20%), Positives = 59/125 (47%), Gaps = 5/125 (4%)

Query: 34  WLGSKLIVFLVDADDIEIILNSHVHI--DKATEY-RFFKPWLGEGLLISSGPKWRSHRKM 90
           +LG K +V + D + +  ++        ++   + RF    + + LL+    +W+  R +
Sbjct: 2   YLGRKPVVVVADPEMLRQVMVKDFSSFPNRMVSFLRFITKPMSDCLLMLRNERWKRVRSI 61

Query: 91  IAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGIS 148
           + P F  + +K  V + N  ++ +++ L   +E  + F++H      T+D++   A G  
Sbjct: 62  LTPAFSASKMKEMVPLINTATDALIKNLDAFAESAEAFNIHKCFGCFTMDVVASVAFGTQ 121

Query: 149 RKTQD 153
             +Q+
Sbjct: 122 VDSQN 126


>UniRef50_UPI00015B5352 Cluster: PREDICTED: similar to cytochrome
           P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 507

 Score =  117 bits (281), Expect = 8e-25
 Identities = 70/240 (29%), Positives = 114/240 (47%), Gaps = 12/240 (5%)

Query: 272 RLAFLDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330
           R   + L+I++ +     K++  +I  +       G ++T++   F L  L  + D+Q R
Sbjct: 269 RQDMMQLLIQAMKKDDGIKVTMDDIIGQAFFFFLAGFESTSSAMCFALQELAANPDIQDR 328

Query: 331 VYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST---- 386
           +  E+           T+   + +KYL+ V+ E+LR YPPV +  R  N++ T       
Sbjct: 329 LRQEIDDEIEQHGGELTYESLVNLKYLDMVMSETLRKYPPVAITNRLCNKEYTFPPLMEG 388

Query: 387 -KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSC 445
              Y +  GT+++I  F LHR PKY+ DPE F+P+ F  EN    + Y+Y+PF  GPR C
Sbjct: 389 YPEYQMEVGTSILISMFGLHRDPKYFPDPEKFDPERFNDENKHKINPYTYMPFGIGPRQC 448

Query: 446 VGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFK----LQGDIILKRAEGFQMKVEPRKRV 501
           +  ++A            R F  + +  EK        +   IL   EG+  K E RK+V
Sbjct: 449 IANRFALMEAKIVIIDILRKF--VVKFTEKSHHPVTLSKKTFILSAEEGYWFKFEGRKKV 506



 Score = 34.7 bits (76), Expect = 5.8
 Identities = 29/121 (23%), Positives = 52/121 (42%), Gaps = 8/121 (6%)

Query: 41  VFLVDADDI-EIILNSHVHIDKATEYRFFK--PWLGEGLLISSGPKWRSHRKMIAPTFHI 97
           V + D D I EI + S  H      +   K  P +G  +    G +W+  R  + P++  
Sbjct: 84  VIIKDPDLIREIFVKSFDHFTDHDAFVTEKMDPIVGRNIFSLRGQRWKEVRNTLTPSYTA 143

Query: 98  NILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETAMGI---SRKTQ 152
             +K    +  + S + V+      E+ + F+  D ++  T D++   A G+   S K Q
Sbjct: 144 ARIKMLFALVAECSKDFVQYFVDHPELAENFEAKDAITRYTNDVVASAAFGVKVDSMKDQ 203

Query: 153 D 153
           D
Sbjct: 204 D 204


>UniRef50_A7DLL5 Cluster: Cytochrome P450; n=1; Methylobacterium
           extorquens PA1|Rep: Cytochrome P450 - Methylobacterium
           extorquens PA1
          Length = 466

 Score =  117 bits (281), Expect = 8e-25
 Identities = 62/225 (27%), Positives = 113/225 (50%), Gaps = 5/225 (2%)

Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           FL  ++ +       +SD ++++EV T +  GH+TTA   S+ + LL  H +V   +  E
Sbjct: 241 FLSALMGARDEDGTAMSDRQLRDEVITFLLAGHETTALVLSWTIHLLSRHPEVDRVLATE 300

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           + +I     R A   D   +++ E  I ES+RLYPP   + R+   D  I    + +  G
Sbjct: 301 IGEIV--VQRAAAIDDVPRLRFAEHTITESMRLYPPAWAVGREARCDCQIG--GFDVRGG 356

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454
           T ++I  ++LHR P+++ +PE F P+ +     Q    ++Y+PF  GPR C+G ++A   
Sbjct: 357 TPILISLWVLHRDPRFFDEPEAFRPERWHQGLAQRLPRFAYMPFGGGPRICIGNRFAMIE 416

Query: 455 XXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
                    + FR +++  E    +   + L+   G ++ +E R+
Sbjct: 417 AVLILTTLVQRFRFVADTNEPVVPIP-SMTLRPRGGVRVIIERRE 460



 Score = 42.7 bits (96), Expect = 0.022
 Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 4/125 (3%)

Query: 24  AQTFGNVIRVWLGSKLIVFLVDADDIE-IILNSHVHIDKATEY-RFFKPWLGEGLLISSG 81
           ++ +G+V+      +L++ L    +IE +++  H +  K   + R      G GLL S G
Sbjct: 48  SRQYGDVVAFRTAGQLMLVLTCPREIERVLVKEHQNFPKNEHFWRQVTALFGNGLLTSKG 107

Query: 82  PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILL 141
             W+  R++ AP F   +L S+       S    E  ++  G+  DVH  M   ++ I  
Sbjct: 108 TFWQRQRRLAAPAFAGPMLASYADAMVHESMLTAEGWRA--GEVRDVHADMMALSLRIAA 165

Query: 142 ETAMG 146
           +   G
Sbjct: 166 KALFG 170


>UniRef50_UPI00005A2E9B Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily A, polypeptide 11; n=1; Canis
           lupus familiaris|Rep: PREDICTED: similar to cytochrome
           P450, family 4, subfamily A, polypeptide 11 - Canis
           familiaris
          Length = 411

 Score =  116 bits (280), Expect = 1e-24
 Identities = 68/206 (33%), Positives = 108/206 (52%), Gaps = 26/206 (12%)

Query: 266 DVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQ 325
           +V  K+ L FLD+   +       +SD +++ EVDT  FEGHDTTA+G S++L  L  H 
Sbjct: 165 EVRNKRHLDFLDISFFAKMENGRGLSDKDLRAEVDTFKFEGHDTTASGISWILYALATHP 224

Query: 326 DVQARVYDELYQIFGDSDRPATFADTL-EMKYLERVILESLRLYPPVPVIARKLNRDVTI 384
           + Q R  +E+  + GD      F + L +M Y    I E+LRLY PVP + R+L++ +T 
Sbjct: 225 EHQQRCREEIQSLLGDG---LCFREHLDQMPYTTMCIKEALRLYLPVPTVGRELSKPITF 281

Query: 385 STKNYVIPAGTTVVIGTFMLHRQPKYYKDPE-------------------VFNPDNFLPE 425
                 +P G  V++  + LH     + +PE                   VF+P  F P+
Sbjct: 282 -PDGRSLPRGFLVLLSFYALHHNSNVWPNPEVERKEELDHTYPGPGVPLQVFDPSRFAPD 340

Query: 426 NTQNRHYYSYIPFSAGPRSCVGRKYA 451
              +RH ++++PFS G R+C+G+ +A
Sbjct: 341 --ASRHSHAFLPFSGGSRNCIGQHFA 364



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 5/87 (5%)

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSN----NVVEKLKSEVGKTFDV 128
           G GLL+ +G  W  HR+M+ P FH +ILK +V +   +      N  E+L S+     ++
Sbjct: 71  GYGLLLLNGEIWFQHRRMLTPAFHYDILKPYVRLMVDSVQVMLVNKWEELLSQ-NSHLEI 129

Query: 129 HDYMSGTTVDILLETAMGISRKTQDES 155
            +++S  T+D +++ A   S + ++ S
Sbjct: 130 FEHVSLMTLDTIMKCAFRPSDQAEEGS 156


>UniRef50_Q0LLJ2 Cluster: Cytochrome P450; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Cytochrome P450 -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 459

 Score =  116 bits (280), Expect = 1e-24
 Identities = 62/227 (27%), Positives = 117/227 (51%), Gaps = 5/227 (2%)

Query: 276 LDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           L +++ S  +G  + ++D ++++EV T+   GH+TTA   ++   LL    +V+ R+  E
Sbjct: 228 LSMLLLSIDDGNGQGMTDQQVRDEVVTLFLAGHETTANTLTWCSYLLSQAPEVRQRLQAE 287

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           + ++     RP T  D  ++ Y E VI E+LR+YPP   ++ ++  +  I+     I   
Sbjct: 288 VDEVL--QGRPVTLQDLQKLPYTEMVIKETLRMYPPAYALSARVPTE-NITVLGQTITPR 344

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454
              ++  + +H  P+Y+ +PE F+P+ F PE  + RH Y+YIPF AG R C+G  +A   
Sbjct: 345 QAAMVSPYAMHHNPRYWPEPERFDPERFSPEQERARHKYAYIPFGAGSRVCIGNVFAMME 404

Query: 455 XXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRV 501
                    +++    + P +  +    I L    G ++++  R+ V
Sbjct: 405 AQLLLATMMQHYDFTLD-PTQRVEYDPQITLGVKHGLRVRLAQRQPV 450



 Score = 40.3 bits (90), Expect = 0.12
 Identities = 29/141 (20%), Positives = 61/141 (43%), Gaps = 4/141 (2%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDI-EIILNSHVHIDK-ATEYRFFKPWLGEGLLISS 80
           Y  +FG+     +G   +  + D   I E+++ +   + K   +      +LG GLL + 
Sbjct: 32  YLASFGDFTTCRMGPFRVYLVNDPAGIQELLVTNRDKVRKNGGDRELLSRFLGNGLLSND 91

Query: 81  GPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDIL 140
           G   +  RK++ P FH+  ++++     +++  ++E+     G   D+   M   T+ I+
Sbjct: 92  GADHQKQRKLVQPAFHMKRIQAYAETMVEHTQAMLERWHD--GAILDMDQAMMELTLTIV 149

Query: 141 LETAMGISRKTQDESGFDYAM 161
            +T        Q+      AM
Sbjct: 150 TKTLFNADISEQEVRQVSQAM 170


>UniRef50_Q5W1K7 Cluster: Cytochrome P450 CYP6AY1 protein; n=3;
           Hemiptera|Rep: Cytochrome P450 CYP6AY1 protein -
           Nilaparvata lugens (Brown planthopper)
          Length = 501

 Score =  116 bits (280), Expect = 1e-24
 Identities = 75/267 (28%), Positives = 124/267 (46%), Gaps = 6/267 (2%)

Query: 204 LTNKVIKNKKETYLENKAKGIIPPTLEEFTH---HSGEILANNAKTLSDTVFKGYRDDLD 260
           L  + + +  +T +  KA  +  P L  F        EI       + DT+    R+D+ 
Sbjct: 205 LMGRRVLDSSQTSVITKAIRVFFPQLFHFLRLRTFPEEIATFFQTVIHDTIENRERNDVQ 264

Query: 261 FNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCL 320
            ND   +  + R    D   + ++    +I++  I  +       G++T++   SF L  
Sbjct: 265 RNDFIPLLMQLRKKSPDY--DGTEANDLEITESVIAAQAFVFFMAGYETSSTTLSFCLYE 322

Query: 321 LGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNR 380
           L  + DVQ +  +E+ ++     + +  A  +++ YLE ++LE++R YPPV V+AR   +
Sbjct: 323 LAKNLDVQEKACNEIKKVLNKHGKLSHEA-LMDLDYLEMILLETMRKYPPVSVLARVCTK 381

Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440
             TI      I  GT+V I  +  H   KY+ DPE F+P+ F PEN +    Y+Y+PF A
Sbjct: 382 PYTIPGTKISIDPGTSVAIPVYSFHHDHKYFPDPETFDPERFSPENQEKSINYTYLPFGA 441

Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFR 467
           GP  C G K+             R FR
Sbjct: 442 GPHVCEGTKFRTGRSGIGLRHLLRLFR 468



 Score = 37.1 bits (82), Expect = 1.1
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 81  GPKWRSHRKMIAPTFHINILKSFVGIF----NQNSNNVVEKLKSEVGKTFDVHDYMSGTT 136
           G KWR  R+ I+P F    LK+   +     +Q SN +   L  +     ++ D M+  T
Sbjct: 121 GEKWRMLRQKISPVFTSGKLKAMFPLLETCSSQLSNYIESALGEQDSSLLEMRDVMARFT 180

Query: 137 VDILLETAMGISRKTQDESGFDYAMAVMKMCD 168
            D++   A G+   +  E   D+ +   ++ D
Sbjct: 181 TDVIGSVAFGLHFNSFTEKESDFQLMGRRVLD 212


>UniRef50_Q309A5 Cluster: Cytochrome P450 monooxygenase; n=22;
           Apocrita|Rep: Cytochrome P450 monooxygenase - Apis
           mellifera (Honeybee)
          Length = 499

 Score =  116 bits (280), Expect = 1e-24
 Identities = 68/248 (27%), Positives = 123/248 (49%), Gaps = 15/248 (6%)

Query: 257 DDLDFNDENDVGEKKRLAFLDLMIESSQNGTN----KISDHEIKEEVDTIMFEGHDTTAA 312
           D + + ++N++    R  F+++++E  +N       K++D  I  +       G +T++ 
Sbjct: 255 DTIKYRNDNNI---VRPDFINMLMELQKNPQKLENIKLTDSLIAAQAFVFFLAGFETSST 311

Query: 313 GSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVP 372
             S  L  L ++QDVQ ++ +E+      +++   + D  EM+YL++V  E+LR+YPP  
Sbjct: 312 TMSNALYELALNQDVQKKLREEINTFCPKNNKELKYDDIKEMEYLDKVFKETLRMYPPAS 371

Query: 373 VIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHY 432
           ++ RK   D T +     IP    + I  F +HR    Y +P+ F+P+ F  +   +RH 
Sbjct: 372 ILMRKAISDYTFNDTKITIPKEMKIWIPAFAIHRDSAIYPNPDSFDPERFDQDAMASRHP 431

Query: 433 YSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEK-----EFKLQGDIILKR 487
             Y+PF  GPR+C+G ++A            RN +   E+ EK     EF   G  +L  
Sbjct: 432 MHYLPFGDGPRNCIGARFAVYQTKVGLITILRNHKV--EVCEKTIIPYEFD-PGAFLLSP 488

Query: 488 AEGFQMKV 495
            +G  +K+
Sbjct: 489 KDGIYLKI 496


>UniRef50_Q27594 Cluster: Cytochrome P450 6a9; n=15;
           Schizophora|Rep: Cytochrome P450 6a9 - Drosophila
           melanogaster (Fruit fly)
          Length = 504

 Score =  116 bits (280), Expect = 1e-24
 Identities = 65/204 (31%), Positives = 108/204 (52%), Gaps = 12/204 (5%)

Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIE-------SSQNGTN-KISDHEIKEEVDTIMFEGH 307
           R+ + F ++N++   +R  F+D +I+        S++G +  ++  E+  +       G 
Sbjct: 254 RETVAFREKNNI---RRNDFMDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGF 310

Query: 308 DTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRL 367
           +T++    F L  L  HQD+Q RV  E  ++ G  +   T+    +M YL++VI E+LRL
Sbjct: 311 ETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISETLRL 370

Query: 368 YPPVPVIARKLNRDVTI-STKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPEN 426
           Y  +PV+ R+   D  +     YVI  G  V+I    +HR  K Y +P  FNPDNF PE 
Sbjct: 371 YTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPER 430

Query: 427 TQNRHYYSYIPFSAGPRSCVGRKY 450
            + R    ++PF  GPR+C+G ++
Sbjct: 431 VKERDSVEWLPFGDGPRNCIGMRF 454


>UniRef50_Q8T624 Cluster: Cytochrome P450 CYP9L1 protein; n=6;
           Cellia|Rep: Cytochrome P450 CYP9L1 protein - Anopheles
           gambiae (African malaria mosquito)
          Length = 533

 Score =  116 bits (279), Expect = 1e-24
 Identities = 71/216 (32%), Positives = 108/216 (50%), Gaps = 4/216 (1%)

Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATF 348
           K+S++E+  +       G DT A   +FVL  + +  ++Q R+Y+E+ Q+    D  A  
Sbjct: 317 KLSENEMIAQCLLFFLAGFDTIATSMTFVLYEVTLAPEIQQRLYEEIQQVSETLDGKALT 376

Query: 349 ADTLE-MKYLERVILESLRLYPPVPVIARKLNRDVTI-STKNYVIPAGTTVVIGTFMLHR 406
            D L+ M+YL+ V+ E+LR + P P   R  N+D TI    + VIP G TV I    LH 
Sbjct: 377 YDALQGMRYLDMVVSETLRKWSPSPGTDRMCNQDYTIPGDPDIVIPKGATVFIPIAGLHY 436

Query: 407 QPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF 466
            P++Y DP+ F+P+ F  EN       +Y+PF  GPR+C+  ++A             N+
Sbjct: 437 DPRFYPDPDRFDPERFNDENKHKIPLGAYLPFGIGPRNCIASRFALMEVKAIVYHILLNY 496

Query: 467 R-TISEIPEKEFKL-QGDIILKRAEGFQMKVEPRKR 500
               SE      KL +G   LK   G  +K  PR +
Sbjct: 497 ELKRSERTSVPVKLAKGFSPLKPENGMYLKFNPRMK 532



 Score = 39.9 bits (89), Expect = 0.16
 Identities = 18/68 (26%), Positives = 36/68 (52%)

Query: 80  SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDI 139
           +G +WR+ R  ++PTF  + ++    +  + S+N+V+ L    G+  +V D     T D+
Sbjct: 129 TGQRWRNVRTTLSPTFTGSKMRQMFAMILECSDNMVQALAHPTGRECEVKDLFIRFTNDV 188

Query: 140 LLETAMGI 147
           +   A G+
Sbjct: 189 IASCAFGV 196


>UniRef50_Q0IEL1 Cluster: Cytochrome P450; n=6; Culicini|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 511

 Score =  116 bits (279), Expect = 1e-24
 Identities = 64/219 (29%), Positives = 108/219 (49%), Gaps = 8/219 (3%)

Query: 284 QNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD 343
           +N    +S  E+  +V      G++T+++  SF L  L  HQD+QA+V+ E+  +  + +
Sbjct: 292 KNAIKSLSIDEVTAQVMVFFVAGYETSSSTVSFCLFELARHQDIQAKVHQEIDTVLAEHE 351

Query: 344 RPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFM 403
              T+A    MKYLE+ + E++R YPPV ++ R+  +   I   + ++  GT +V+    
Sbjct: 352 GNLTYASLASMKYLEQCLEETVRKYPPVAILNRECTKTYRIPETDVIVEKGTPIVVPLMG 411

Query: 404 LHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXX 463
           +HR P+Y+  P  F PD F     Q++ Y+    F AGPR C+G +              
Sbjct: 412 MHRDPQYFPQPNDFQPDRF-EGGAQSKAYFG---FGAGPRLCIGMRLGILQSKVAVVTLL 467

Query: 464 RNFRTISEIPE---KEFKLQ-GDIILKRAEGFQMKVEPR 498
           R F+     PE    E +++    IL    G Q+ V+ R
Sbjct: 468 RKFKFSLANPEDQHTELRMKPRSFILTTEGGIQLVVQQR 506



 Score = 34.7 bits (76), Expect = 5.8
 Identities = 24/102 (23%), Positives = 45/102 (44%), Gaps = 8/102 (7%)

Query: 48  DIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIF 107
           D E   +  +H+D+ T+     P  G  L    G KW++ R  + PTF    LK    + 
Sbjct: 93  DFEHFHDRGIHVDEETD-----PMSGH-LFALGGVKWKNLRAKLTPTFSSGSLKEMFPLL 146

Query: 108 NQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLETAMGI 147
            + +  + ++   E+   +  +V +  +  T D++   A GI
Sbjct: 147 VEKATVLQKRFLKEIATSEVVEVKELAACYTSDVIASVAYGI 188


>UniRef50_O16156 Cluster: Cytochrome P450 30; n=1; Mercenaria
           mercenaria|Rep: Cytochrome P450 30 - Mercenaria
           mercenaria (Northern quahog) (Venus mercenaria)
          Length = 515

 Score =  116 bits (279), Expect = 1e-24
 Identities = 98/445 (22%), Positives = 200/445 (44%), Gaps = 40/445 (8%)

Query: 28  GNVIRVWLGSKLIVFLVDADDIEIIL--NSHVHIDKATEYRFFKPWLGEGLLISSGPKWR 85
           G +  ++LG+   + + D D I+ I+  +     D+ +  +  K W    + ++SG  WR
Sbjct: 71  GKIFGLYLGNIPTLVISDTDIIKQIMVKDFSKFTDRVSLVQVTKKWKS-AVSVASGEHWR 129

Query: 86  SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT---FDVHDYMSGTTVDILLE 142
             R  ++PTF    ++      ++    ++E L  +  +    F++   +SG T+D++  
Sbjct: 130 FLRTTLSPTFTTGKIREMKPYIHKCMKTLLELLSEKTDQNPEGFNIVPNLSGYTLDVICS 189

Query: 143 TAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIH 202
           T  G+    Q +      + +    + +  R     +R+ + F +  FF   + + G + 
Sbjct: 190 TGFGLDVDAQKDPD---NLIIRYAREFLEFRG----LRNPL-FLVQMFFPDLSSIFGRL- 240

Query: 203 GLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFN 262
            L   ++ N+   +  +  K       +  + H         + L   +   ++ +L   
Sbjct: 241 -LETNIVSNEAFDFYMSTMKKAFTDRKQAQSKH---------RDLLQLLINTHKGELG-- 288

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
            EN++ + +   F  +     Q G   ++D E+       M  G+DTTA   S+++  L 
Sbjct: 289 -ENEI-DTEETTFEGM----KQRG---LTDEEVLLNSIIFMVAGYDTTATTLSWIVYDLV 339

Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382
            + + Q ++ +E+    G+S+   T+ +  +++YL+ V+ E+LR++PP   I R    DV
Sbjct: 340 TNTECQEKLIEEIDAEIGESE--TTYDNVFKLRYLDMVVNETLRMHPPAQRINRLALEDV 397

Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442
            I+     I  G         LH  P+Y+++P  ++P+ F PEN  N + Y+Y+PF  GP
Sbjct: 398 KIN--GLQILKGMDCTFSILALHYMPEYWENPYKYDPERFAPENQANINQYAYMPFGQGP 455

Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFR 467
           R+C+G++ A            + FR
Sbjct: 456 RNCIGKRLALLEVKATVVVLLQKFR 480


>UniRef50_Q9VGB4 Cluster: Probable cytochrome P450 313a2; n=2;
           Drosophila melanogaster|Rep: Probable cytochrome P450
           313a2 - Drosophila melanogaster (Fruit fly)
          Length = 493

 Score =  116 bits (279), Expect = 1e-24
 Identities = 73/242 (30%), Positives = 123/242 (50%), Gaps = 6/242 (2%)

Query: 259 LDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318
           L+ N EN   E +    +   IE  +N  +++S  E+  E  +++    +T+A    + L
Sbjct: 254 LNSNPENYC-ESELKTVIHRAIELFRN--DEMSLMELGAECSSMVLAAFETSAHTVYYAL 310

Query: 319 CLLGIHQDVQARVYDELYQIFGDSDR-PATFADTLEMKYLERVILESLRLYPPVPVIARK 377
            LL +  + Q  V++E+ + F  +     T  D  ++ YL+RV+ E+LRL P VP  +R+
Sbjct: 311 VLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRE 370

Query: 378 LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYI 436
              D+ +S    VIP G T+ I  F   R   Y+  +   FNP+NFLPE   +RH Y++I
Sbjct: 371 TLEDLRLSN-GVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFI 429

Query: 437 PFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVE 496
           PFS G R+C+G +Y             RN++  +  P +  +    +++K A+  Q+  E
Sbjct: 430 PFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSPQLAFE 489

Query: 497 PR 498
            R
Sbjct: 490 RR 491



 Score = 61.7 bits (143), Expect = 4e-08
 Identities = 55/233 (23%), Positives = 103/233 (44%), Gaps = 7/233 (3%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY-RFFKPWLGEGLLISSG 81
           Y    G+    W+G+  IV   D    E +L S   I+++++        +G GLL   G
Sbjct: 61  YMDKHGSTYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTLQG 120

Query: 82  PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK-TFDVHDYMSGTTVDIL 140
            KW + RK + P F  ++L SF+ IFN  ++ +V    S VG+   DV   +   +  I 
Sbjct: 121 SKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIA 180

Query: 141 LETAMGISRKTQDESGFDYAM-AVMKMCDIIHQRHYKFWMRSEIVFKLTSF----FKQQT 195
            +T +G      D    D  +     M  +     +  +++++IV KL        +  +
Sbjct: 181 TQTTLGTDVTKDDNFENDAILKTYQSMLRLTIINIFVPFVQNKIVSKLFGLEWLRRRDAS 240

Query: 196 KLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLS 248
            +  +I+ + +K + +  E Y E++ K +I   +E F +    ++   A+  S
Sbjct: 241 AINKMINNILDKKLNSNPENYCESELKTVIHRAIELFRNDEMSLMELGAECSS 293


>UniRef50_Q5U3Q3 Cluster: Cytochrome P450, family 3, subfamily c,
           polypeptide 1 like, 2; n=4; Danio rerio|Rep: Cytochrome
           P450, family 3, subfamily c, polypeptide 1 like, 2 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 494

 Score =  116 bits (278), Expect = 2e-24
 Identities = 64/219 (29%), Positives = 111/219 (50%), Gaps = 4/219 (1%)

Query: 282 SSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGD 341
           +S+     ++DHEI  +    +  G++TT+   SF+L  L  + D   ++ +E+ + F  
Sbjct: 278 TSEQPVKGLTDHEILSQSFIFILGGYETTSTTLSFLLHNLATNPDCLEKLVEEIDKNF-P 336

Query: 342 SDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGT 401
            D P ++   ++M YLE  I ES+RL P  P + R   +  T+      IP  T V I T
Sbjct: 337 LDTPISYDALMKMDYLEMSINESMRLLPTAPRLERVCKK--TVELNGITIPKDTLVAIPT 394

Query: 402 FMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXX 461
           ++L+R P+ +  P+ F P+ F PEN      Y+++PF  GPR+C+G ++A          
Sbjct: 395 YVLNRDPQLWDSPQEFRPERFSPENKSEFLQYAFMPFGLGPRNCIGMRFALMIVKLLVVK 454

Query: 462 XXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500
             +NF ++    E +  L+   + +      +K+ PRKR
Sbjct: 455 LLQNF-SLETCKETQIPLELTPVFQPKVPITLKLTPRKR 492


>UniRef50_Q56JT9 Cluster: Cytochrome P450 monooxygenase; n=10;
           Endopterygota|Rep: Cytochrome P450 monooxygenase -
           Tribolium castaneum (Red flour beetle)
          Length = 463

 Score =  116 bits (278), Expect = 2e-24
 Identities = 92/389 (23%), Positives = 173/389 (44%), Gaps = 39/389 (10%)

Query: 69  KPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDV 128
           +P L E L    G KW+  R  ++P F  + +K+   + ++ + N V+  +    +  ++
Sbjct: 69  EPLLSEALTNLPGEKWKEMRATLSPAFTSSKIKNMYSLISECAENFVDFFQGRE-QDVEI 127

Query: 129 HDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLT 188
            +  S  + D++   A GI   +  E   ++      +      +  K ++ + +V K+ 
Sbjct: 128 KEVFSRFSNDVIATAAFGIRVNSVQEPNNEFYAMGRSLTTFSAFQILKIFL-AHLVPKIA 186

Query: 189 SFFKQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLS 248
            FF+              +V+  K   + E    G+I   L+       E +      L 
Sbjct: 187 EFFEY-------------RVLPRKVTDFFE----GLI---LDNMQKREAEKIVR--PDLI 224

Query: 249 DTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTN----KISDHEIKEEVDTIMF 304
             + +  +  L  ++ N+ GE     F    +E S+ G N    +++D +I  +     F
Sbjct: 225 HLLMEARKGKLKHDNSNEGGE----GFAT--VEESEIGKNTKQVELTDEKIVAQALLFFF 278

Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364
            G +T + G SF+   L  +  VQ ++  E+     ++    ++     MKYL++V+ ES
Sbjct: 279 AGFETVSTGVSFMAYELATNPHVQKKLQKEIDLTLQENHGKISYNVLQSMKYLDQVVCES 338

Query: 365 LRLYPPVPVIARKLNRDVTIST-----KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNP 419
           LRL+PP P   R  N++  I       + + +   T V+I  F +HR P+Y+ DPE F+P
Sbjct: 339 LRLWPPAPQTDRLCNKNFVIEASKPHERTFTVEKDTMVMISMFAIHRDPQYFPDPEKFDP 398

Query: 420 DNFLPENTQNRHYYSYIPFSAGPRSCVGR 448
           + F  EN       +Y+PF  GPR+C+ +
Sbjct: 399 ERFSDENKAKIVPGTYMPFGVGPRNCIAK 427


>UniRef50_UPI0000D56564 Cluster: PREDICTED: similar to Probable
           cytochrome P450 6a17 (CYPVIA17); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Probable cytochrome
           P450 6a17 (CYPVIA17) - Tribolium castaneum
          Length = 471

 Score =  115 bits (277), Expect = 3e-24
 Identities = 68/230 (29%), Positives = 115/230 (50%), Gaps = 9/230 (3%)

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
           +E   G+  R  FL +++E  +    +I+  EI  +    +  G  T+    +F L  L 
Sbjct: 238 EERKKGQTGRNDFLQVLVEMEKKF--EITIDEIAAQCFIFLIAGMSTSPTAMTFALYELA 295

Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382
            HQD+Q +V  ++ + FG      T+    EMKYL +V  E+LR+YPP   + RK  R+ 
Sbjct: 296 RHQDIQEKVRQDIAK-FGK----VTYDSLQEMKYLGQVFDETLRMYPPAAYLNRKCERNY 350

Query: 383 TIST-KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441
            I      ++  GT V I    +H    YY DPE F+P++F  EN + R  ++++PF  G
Sbjct: 351 EIPDGSGIIVEKGTIVAIPVLGIHYDRDYYPDPEKFDPEHFSEENKRLRPNFAFLPFGEG 410

Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQGDIILKRAEG 490
           PR C+G ++             + ++ T+SE   +  K++ + ++  AEG
Sbjct: 411 PRICIGMRFGLMQSKLGLVSLLKRYKFTVSEKTREPLKMKPNSLVLSAEG 460


>UniRef50_A7RQ80 Cluster: Predicted protein; n=5; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 459

 Score =  115 bits (277), Expect = 3e-24
 Identities = 68/264 (25%), Positives = 133/264 (50%), Gaps = 12/264 (4%)

Query: 197 LLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYR 256
           +L I+ G+ + V  N  +         +   T ++       ++    K +   VF  + 
Sbjct: 150 ILRIVFGIESSVQHNYDDPAFVAARSALEASTFQKIAGAVVGMMPKPIKKMFSRVFFSHT 209

Query: 257 DDLDFNDENDVGEKK------RLAFLDLMIES---SQNGTNKISDHEIKEEVDTIMFEGH 307
            +L    E  +  KK      R   LDLM+E+    +    ++++ EI  +    M  G+
Sbjct: 210 KELVEMTEKVIAAKKTQENSTRKDILDLMLEAMIDDETKKKRMTEAEIIAQCLIFMIAGY 269

Query: 308 DTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRL 367
           + T +  +F+   L  + D+Q ++  E+  ++ D+D+  ++    E+ YL+ V+ E+LR+
Sbjct: 270 EGTNSALTFICYNLATNPDIQEKLQQEIDSVWTDADQVLSYDILNELSYLDMVVSETLRM 329

Query: 368 YPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENT 427
           YPP  ++ R + +D  I  + +    G  +++  + LH  P+ + +PE FNP+ F  E  
Sbjct: 330 YPP-GMLTRAVTQDCVIQGRRF--RKGNAILMDVYSLHHDPELWPEPERFNPERFTAEAK 386

Query: 428 QNRHYYSYIPFSAGPRSCVGRKYA 451
           Q+R+  +Y+PFSAGPR+CVG +++
Sbjct: 387 QSRNPCAYLPFSAGPRNCVGMRFS 410



 Score = 48.4 bits (110), Expect = 4e-04
 Identities = 49/217 (22%), Positives = 95/217 (43%), Gaps = 15/217 (6%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHI--DKATEYRFFKPWLGEGLLISS 80
           Y++T+G V  ++L     + + D D ++ +L    H   D+   +   +P+    +  + 
Sbjct: 30  YSRTYGRVYGLYLFGSPTIVINDPDILKEVLVKEFHSFHDRPAFFPMPEPF-DSMMFFAE 88

Query: 81  GPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVD 138
           G  W   R  ++P F  + +K  + + N + + ++ KL+  +E G+ F+++      T+D
Sbjct: 89  GETWHRVRTTVSPIFSAHKMKMVLPLMNNSCDIMMSKLQQAAEKGEPFNMYRMGQSLTMD 148

Query: 139 ILLETAMGISRKTQ---DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTS--FFKQ 193
            +L    GI    Q   D+  F  A + ++             M  + + K+ S  FF  
Sbjct: 149 FILRIVFGIESSVQHNYDDPAFVAARSALEASTFQKIAGAVVGMMPKPIKKMFSRVFFSH 208

Query: 194 QTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLE 230
             +L+     +T KVI  KK T   +  K I+   LE
Sbjct: 209 TKELV----EMTEKVIAAKK-TQENSTRKDILDLMLE 240


>UniRef50_UPI0000D56E82 Cluster: PREDICTED: similar to Cytochrome
           P450 9c1 (CYPIXC1); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 9c1 (CYPIXC1) -
           Tribolium castaneum
          Length = 480

 Score =  114 bits (275), Expect = 4e-24
 Identities = 66/231 (28%), Positives = 115/231 (49%), Gaps = 12/231 (5%)

Query: 276 LDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDEL 335
           + LM+E+++   N+++D +I  +  T  F G +T A   SF+   L IH ++Q ++  E+
Sbjct: 254 IHLMLEANKGQANQLTDDDIVAQAMTFFFAGFETVATACSFMAYELAIHPEIQQKLQAEI 313

Query: 336 YQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNY-----V 390
             + G      T+   L MK+L++V+ ESLRL+PP   I R   +   I  KN+     V
Sbjct: 314 DSVGG-----VTYESLLSMKFLDQVVSESLRLWPPGFQIERMCTKSYKIEPKNHNEKGIV 368

Query: 391 IPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKY 450
           +  G +++I    LH  P  + +P+ F+P+ F   N       SY+PF  GPR+C+  ++
Sbjct: 369 LEEGVSLIIPVIALHHDPDLFPEPDRFDPERFSEANRSQIVPGSYLPFGVGPRNCIASRF 428

Query: 451 AXXXXXXXXXXXXRNFRTIS-EIPEKEFKLQ-GDIILKRAEGFQMKVEPRK 499
           A              F  +  +  +   KL    + L+  +GF++ + PRK
Sbjct: 429 ALLEIKTLFFHMLSKFDIVPIDTTQIPLKLSTKKMHLEPEKGFRLGIRPRK 479



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 23/78 (29%), Positives = 38/78 (48%)

Query: 70  PWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVH 129
           P LG+ LL+ +G  W+  R  ++P +  N LK+   +  + + N V   K       D+ 
Sbjct: 106 PILGKSLLMLNGQDWKQMRATLSPAYTTNKLKNMHQLMTECAQNFVGHFKGREKVAVDMK 165

Query: 130 DYMSGTTVDILLETAMGI 147
           D  +  T D++  TA GI
Sbjct: 166 DIFTRFTTDVIASTAFGI 183


>UniRef50_Q178V0 Cluster: Cytochrome P450; n=2; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 502

 Score =  114 bits (275), Expect = 4e-24
 Identities = 70/242 (28%), Positives = 123/242 (50%), Gaps = 5/242 (2%)

Query: 260 DFNDENDVGEKKR-LAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318
           D N+++D  + +R   F+D ++ S  N    IS   + E++ TIM  G+DT+A   +   
Sbjct: 264 DENEDDDGYQIRRPKLFIDQVL-SGNNTEADISTQNLSEQILTIMAAGYDTSANMVAHSC 322

Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKL 378
             L I  ++Q +V  E+  +  D ++  T     ++ YL++   E LRL P    IAR  
Sbjct: 323 LFLAIFPELQEKVAQEIQTVLPDCEQELTAETLKDLPYLDKFFKECLRLTPVGSTIARVN 382

Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKD-PEVFNPDNFLPENTQNRHYYSYIP 437
             D+ +      IP G   +   ++LHR+   +    E F+P+NF PE ++ RH ++++P
Sbjct: 383 MTDIELDGCR--IPKGNIFIFNFYVLHRRKDIWGPYAEQFDPENFSPERSKGRHPFAFLP 440

Query: 438 FSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
           FS G R+C+G +YA            RNFR  ++I  ++ K + ++ L  A    + +E 
Sbjct: 441 FSGGSRNCIGARYAMISNKIMIIHLVRNFRMSTKIRFEDLKYRINVTLNLAFKHLITLEA 500

Query: 498 RK 499
           R+
Sbjct: 501 RR 502



 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 34/118 (28%), Positives = 63/118 (53%), Gaps = 3/118 (2%)

Query: 34  WLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAP 93
           WLG +L+ ++   + ++ +L      +K   Y F +  L  GL  +    W+ +RK + P
Sbjct: 74  WLGPQLMFYVAHPELVQKVLTDPNCSEKPFFYEFSR--LTHGLFSAKYSIWKPNRKALNP 131

Query: 94  TFHINILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTVDILLETAMGISRK 150
           T ++ +L SFV IF + S ++VEKLK    G   D+ D+ +   ++++  T +G + K
Sbjct: 132 TMNVKMLNSFVPIFERFSRSMVEKLKCYPEGTPVDILDFTTECALEMVCGTTLGTALK 189


>UniRef50_A7RSL1 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 510

 Score =  114 bits (275), Expect = 4e-24
 Identities = 57/184 (30%), Positives = 99/184 (53%), Gaps = 6/184 (3%)

Query: 272 RLAFLDLMIESSQN----GTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327
           R   LDLM+E++ +    G   +S   I       +  GH+TT++  +F    L  +  +
Sbjct: 282 RKDMLDLMLEAAASDNTDGGKALSLDAIIANTIVFLLAGHETTSSTIAFASYFLAKNPKI 341

Query: 328 QARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387
           Q ++  E+  ++   +   ++    ++ YLE VI E+LRL PP   + R+  +   I+  
Sbjct: 342 QEKLQQEIDSVWSGEEEMPSYDTVHDLPYLEMVISETLRLCPPGFAVIRECTKTCIINKL 401

Query: 388 NYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447
              IP G+ V+   + +HR PKYY DP++F+P+ F PE   +R  Y+Y+PF  GP +C+G
Sbjct: 402 R--IPQGSRVLASVYSIHRDPKYYPDPDIFDPERFSPEGKASRDPYAYMPFGHGPHNCIG 459

Query: 448 RKYA 451
            ++A
Sbjct: 460 MRFA 463



 Score = 50.8 bits (116), Expect = 8e-05
 Identities = 35/133 (26%), Positives = 61/133 (45%), Gaps = 2/133 (1%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGP 82
           Y Q  G  IR+    K  + + D   ++ I+  +           F P L + L I  G 
Sbjct: 78  YKQYEGPAIRLSFMGKPSILVKDTALLKAIMVKNFDCFHDRLKADFSPPLDKMLTILPGE 137

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDIL 140
           +WR+ R  ++P F  + LK  V + N+  +  ++K+   +E G+T DV       T+DI+
Sbjct: 138 EWRNLRHALSPNFSAHKLKGMVPLMNKACDVYMKKIACAAETGETIDVMKINPALTLDII 197

Query: 141 LETAMGISRKTQD 153
           +  A G+    Q+
Sbjct: 198 ISCAFGVESDCQN 210


>UniRef50_Q8WQM9 Cluster: Cytochrome P450 CYP6M1; n=7;
           Culicidae|Rep: Cytochrome P450 CYP6M1 - Anopheles
           gambiae (African malaria mosquito)
          Length = 503

 Score =  114 bits (274), Expect = 6e-24
 Identities = 56/206 (27%), Positives = 106/206 (51%)

Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMF 304
           K +S    K  RD +D+  +N +     +  +  M+  ++N    ++ +E+  +     F
Sbjct: 243 KEVSAFFLKVVRDTIDYRVKNGIQRNDFMDLMIRMLRDTENPEEALTFNEVAAQAFVFFF 302

Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364
            G +T++   ++ L  L ++ +VQ +    + ++    +   T+    +MKYL++++ ES
Sbjct: 303 AGFETSSTLLTWTLYELALNPEVQEKGRQCVQEVLAKHNGEMTYDAIHDMKYLDQILKES 362

Query: 365 LRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP 424
           LR YPPVP+  R   +D  +   + VI AGT + I  F + R    + +PE F+P+ F  
Sbjct: 363 LRKYPPVPMHFRMTAQDYRVPDTDSVIEAGTMLFIPIFSIQRDASLFPEPEKFDPERFSA 422

Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKY 450
           E    RH +++ PF  GPR C+G ++
Sbjct: 423 EEEAKRHPFAWTPFGEGPRVCIGLRF 448


>UniRef50_Q8MZK0 Cluster: Cytochrome P450; n=6; Culicidae|Rep:
           Cytochrome P450 - Anopheles gambiae (African malaria
           mosquito)
          Length = 505

 Score =  114 bits (274), Expect = 6e-24
 Identities = 61/211 (28%), Positives = 101/211 (47%), Gaps = 1/211 (0%)

Query: 281 ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG 340
           + +  G  K++  E+  +     F G +T++   SF L  L  + D+Q RV  E+ +   
Sbjct: 286 DETTEGLQKLTLDEVAAQAFVFFFAGFETSSTTLSFALFELANNPDIQERVRAEMLEKLQ 345

Query: 341 DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIG 400
             D   T+    EM YL++VI E+LR+YPPVP + R   +   +   N  +   T ++I 
Sbjct: 346 LHDGKITYDALKEMTYLDQVINETLRMYPPVPQLIRVTTQPYKVEGANVSLEPDTMLMIP 405

Query: 401 TFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXX 460
            + +H     Y DPE F+PD F    T  RH ++++PF  GPR+C+G ++          
Sbjct: 406 IYAIHHDASIYPDPERFDPDRFALAATHARHTHAFLPFGDGPRNCIGMRFGLLEVKFGIV 465

Query: 461 XXXRNFR-TISEIPEKEFKLQGDIILKRAEG 490
                 R T+SE  +   ++     +  AEG
Sbjct: 466 QMVSKLRFTVSERMQMPLRMSKTASILEAEG 496


>UniRef50_Q695H1 Cluster: Antennae-rich cytochrome P450; n=3;
           Polyphaga|Rep: Antennae-rich cytochrome P450 -
           Phyllopertha diversa (Pale-brown chafer beetle)
          Length = 507

 Score =  114 bits (274), Expect = 6e-24
 Identities = 59/187 (31%), Positives = 96/187 (51%), Gaps = 4/187 (2%)

Query: 267 VGEKKRLAFLDLMIESSQNGT---NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 323
           +    R   +D++I+    G     K   + +  +       G +TT++  S+ L  L +
Sbjct: 264 IENSSRNDLIDILIKLQTEGDFDGYKFEGNRVIAQAAQFFLAGFETTSSTISYALYELCL 323

Query: 324 HQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVT 383
           ++ +Q +V  E+           ++    +MKYL +V+ E LR YP +P + RK   D  
Sbjct: 324 NKPIQEKVVTEIKSAL-QQHGSVSYEAIQDMKYLHKVVQEILRKYPVLPFLDRKTTMDWK 382

Query: 384 ISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443
           I   N  + AGT V I  F LH  PKY+ +P+VF+P+ F  E T +R  +SYIPF  GPR
Sbjct: 383 IPGTNITLEAGTPVYIPMFGLHYDPKYFPNPDVFDPERFTEETTNSRPCFSYIPFGGGPR 442

Query: 444 SCVGRKY 450
           +C+G ++
Sbjct: 443 NCIGERF 449


>UniRef50_UPI00015B4FBC Cluster: PREDICTED: similar to cytochrome
           P450 monooxygenase; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to cytochrome P450 monooxygenase -
           Nasonia vitripennis
          Length = 568

 Score =  113 bits (273), Expect = 8e-24
 Identities = 60/213 (28%), Positives = 105/213 (49%), Gaps = 1/213 (0%)

Query: 256 RDDLDFNDENDVGEKKRLAFL-DLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGS 314
           +  +++  +N+V     +  L D+  + S+ G  +++D  I  +       G +T++   
Sbjct: 323 KQTMEYRKKNNVRRNDFVDLLMDIKDDPSKVGDIEMTDALITAQAFVFFIAGFETSSTTI 382

Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374
           S  L  L ++  VQ ++ +E+ +   + +    +     MKYL +V  E+LR YPPV V+
Sbjct: 383 SNALYELALNPSVQEKLREEIIEELANDNGSLKYETIKGMKYLHKVFCETLRKYPPVTVM 442

Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434
            RK  +  T S     IP G  V I  + + R P  Y DP+ F+P+ F  E+ + RH   
Sbjct: 443 MRKSMQPYTFSGTKVTIPKGMRVWIPAYAIQRDPAIYPDPDTFDPERFSEESIKQRHPSF 502

Query: 435 YIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467
           Y+PF  GPR+C+G ++A            RN++
Sbjct: 503 YLPFGDGPRNCIGARFANYQSKIGIIQVLRNYK 535


>UniRef50_A0NQ01 Cluster: Cytochrome P450; n=1; Stappia aggregata
           IAM 12614|Rep: Cytochrome P450 - Stappia aggregata IAM
           12614
          Length = 476

 Score =  113 bits (273), Expect = 8e-24
 Identities = 64/221 (28%), Positives = 109/221 (49%), Gaps = 5/221 (2%)

Query: 279 MIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQI 338
           ++E+       +S   I  E   I   GH+TTA   ++   LL      +A++  EL  +
Sbjct: 260 LLEARDENGEPLSRDAIISEAAVIFMAGHETTANTLAWAWFLLSQCDKSRAKLQAELDTV 319

Query: 339 FGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVV 398
              + R  TF D   + Y + VI E+LRLYPPVP++AR+   D +I  K+  +P G+ V+
Sbjct: 320 L--AGRSPTFQDVPNLPYTKAVIEETLRLYPPVPILAREAMADTSIGGKS--VPKGSLVM 375

Query: 399 IGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXX 458
           +  +++HR P  +  P+VF+P  FL   ++  + Y Y+PFS GPR C G ++        
Sbjct: 376 VVPWLMHRNPVLWSKPDVFDPGRFLNPKSKKPNKYGYVPFSIGPRICAGLQFGMTEAILS 435

Query: 459 XXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
                ++F  +      + +    + L+  E   M + PR+
Sbjct: 436 LAILAQDFE-LKLKEGTDVQPVARLTLRPGENLPMTLHPRR 475



 Score = 37.9 bits (84), Expect = 0.63
 Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 8/107 (7%)

Query: 69  KPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQN-SNNVVEKLKSEVGKTFD 127
           +P LG+GL IS    W   RK++AP  H + ++ F  I  +       +      G   D
Sbjct: 104 QPLLGDGLFISDTETWAKRRKVVAPIIHGSRVRGFAPIMIETIEEKRADWAVQGEGAEVD 163

Query: 128 VHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRH 174
               M+  T +I+  T  G       + G DYA  V++     +QRH
Sbjct: 164 ALADMAHLTAEIICRTIFG------RQLGKDYAAEVVQGFS-DYQRH 203


>UniRef50_Q9GQM9 Cluster: Cytochrome P450 6l1; n=1; Blattella
           germanica|Rep: Cytochrome P450 6l1 - Blattella germanica
           (German cockroach)
          Length = 503

 Score =  113 bits (273), Expect = 8e-24
 Identities = 54/158 (34%), Positives = 83/158 (52%)

Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349
           +S+HE+  +       G +TT++  +F +  L +H ++Q R+  E+ ++        T+ 
Sbjct: 283 VSEHEVLGQAMLFFAAGFETTSSAMAFAMYELALHPEIQDRLRTEIQEVTACHGGQVTYE 342

Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409
              +M YL+ V+ E LR YPP+  I R    D  I   + VI  GT + +    LHR   
Sbjct: 343 GVKKMSYLDMVVSEVLRKYPPMSFIDRVCLHDYHIPGTDVVIEKGTPIFVSLLGLHRDSI 402

Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447
           +Y DPE FNP+ F  E     H +SYIPF  GPR+C+G
Sbjct: 403 FYPDPEDFNPERFNKEKKSGVHPFSYIPFGDGPRNCIG 440


>UniRef50_Q9VGB5 Cluster: Probable cytochrome P450 313a5; n=2;
           Drosophila melanogaster|Rep: Probable cytochrome P450
           313a5 - Drosophila melanogaster (Fruit fly)
          Length = 487

 Score =  113 bits (273), Expect = 8e-24
 Identities = 66/212 (31%), Positives = 110/212 (51%), Gaps = 3/212 (1%)

Query: 289 KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIF-GDSDRPAT 347
           ++S  ++  E   I+F   DT +   + VL L+ +    Q  V++EL ++F    +  A+
Sbjct: 276 ELSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEAS 335

Query: 348 FADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ 407
            AD  ++  L+RV+ E++RL P VP++ R+ +  + +S   Y IP G T++I  F  HR 
Sbjct: 336 HADLEKLVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFY-IPEGVTLMIDIFHTHRN 394

Query: 408 PKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF 466
              +      FNPDNFLPEN + R  YSY+PFS G ++C+G K +            RN+
Sbjct: 395 KDIWGPQANAFNPDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNY 454

Query: 467 RTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
              +    K+ +   +  +K AE   + V+ R
Sbjct: 455 MLSTTFLYKDLRFIDNTTMKLAEQPLLAVKRR 486



 Score = 45.6 bits (103), Expect = 0.003
 Identities = 41/199 (20%), Positives = 88/199 (44%), Gaps = 4/199 (2%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEY-RFFKPWLGEGLLISSGPKWR 85
           +G  +  W+G   ++   +   +E I  S    ++++   +     LG GLL      W 
Sbjct: 64  YGKTVLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWN 123

Query: 86  SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV-GKTFDVHDYMSGTTVDILLETA 144
             RK++ P+F  N + SFV + N  +N +V  L   V G   ++   ++  +  I  +  
Sbjct: 124 ERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINLLPELNKWSFKIAAQIT 183

Query: 145 MGISRKTQ-DESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHG 203
           MG   + Q +    +   +   + ++I       W+R++ + KL S+ K++ +     + 
Sbjct: 184 MGDEVRNQANYQNGNLLESYKALNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSNA 243

Query: 204 LTNKVIKNKKETYLENKAK 222
               +I +KK +  +N ++
Sbjct: 244 FIKDII-DKKLSSTDNSSE 261


>UniRef50_Q0LL77 Cluster: Cytochrome P450; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Cytochrome P450 -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 446

 Score =  113 bits (272), Expect = 1e-23
 Identities = 57/162 (35%), Positives = 92/162 (56%), Gaps = 4/162 (2%)

Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349
           ++D ++++E+ T+   GH+TTA   ++   LL  H  +  ++ DE+    G   R  T  
Sbjct: 243 MTDTQVRDELMTLFLAGHETTANALTWTWYLLAHHPHIATKIKDEVDSTVGT--RLPTMD 300

Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409
           D  ++ Y  +V  ESLRLYPPV +IARK ++   + +  Y +P G   V+  + +HR+  
Sbjct: 301 DLSKLPYTLQVFKESLRLYPPVYMIARKASQAFELGS--YHVPEGMAFVVSPYTIHRRAD 358

Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           Y+  PE FNPD F   +  +    +YIPFS GPR+C+G  +A
Sbjct: 359 YFDHPEDFNPDRFDTSHEASIPKNAYIPFSLGPRNCIGNHFA 400



 Score = 45.2 bits (102), Expect = 0.004
 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 4/124 (3%)

Query: 34  WLGSKLIVFLVDADDIEIILNSHVH-IDKATEYR-FFKPWLGEGLLISSGPKWRSHRKMI 91
           +LGS  +VF+  A+    IL  H   ++K+   R + +P LG GLL S     R  RK++
Sbjct: 44  YLGSYPVVFINSAEYAHGILVQHAQSVEKSLMLRKYMRPLLGNGLLTSENSFHRRQRKLV 103

Query: 92  APTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKT 151
           AP F    + ++    +  ++    + +   G+  D+   M   T+ ++ +T       T
Sbjct: 104 APAFQHRHIANYANTISAYTDET--QARWHQGQRIDIAQEMMRLTLRVMSQTLFSTDINT 161

Query: 152 QDES 155
           + ++
Sbjct: 162 EADA 165


>UniRef50_Q8MTC8 Cluster: Cytochrome P450 monooxygenase CYP321A1;
           n=1; Helicoverpa zea|Rep: Cytochrome P450 monooxygenase
           CYP321A1 - Heliothis zea (Corn earworm) (Bollworm)
          Length = 499

 Score =  113 bits (272), Expect = 1e-23
 Identities = 64/217 (29%), Positives = 106/217 (48%), Gaps = 12/217 (5%)

Query: 271 KRLAFLDLMIESSQNGTNK--ISDHEIKEEVDTIMFE-------GHDTTAAGSSFVLCLL 321
           KR  F DL ++  +NGT K   + +E++     +  +       G +  A G      LL
Sbjct: 260 KRHDFADLCVQLQKNGTLKDQATGYELEPTTGLLSAQAFFFFTAGVEPAADGIFATFALL 319

Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381
             H ++  +V+ E+ + F   D   T+    +M+Y+++V+ ESLR++PP+  + R+   D
Sbjct: 320 SQHPEILQKVHQEIDEYFEKYDGKITYDVVCDMEYVDKVLSESLRMFPPIGFLTRQCIHD 379

Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441
             +   N  +  GT +    + +H  PKYY DPEVF+P+ F  E   N     Y+PF  G
Sbjct: 380 TVLPVGNVKVAKGTKLFTPIYEIHHDPKYYPDPEVFDPERFFKERRPNDDL--YMPFGMG 437

Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFK 478
            R+C+G +Y             R+F T+  IPE + K
Sbjct: 438 NRTCIGARYFKLQLLAAIVHVLRSF-TLKPIPESQQK 473



 Score = 35.1 bits (77), Expect = 4.4
 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 1/82 (1%)

Query: 41  VFLVDADDIEIILNSHVHIDKATEYRFFK-PWLGEGLLISSGPKWRSHRKMIAPTFHINI 99
           +F++DA +++ +L+S             +   L E + + +GPKW+  RK + P F  + 
Sbjct: 82  LFVIDAKNVQHVLSSDFQSFNHRGLDSVEGDQLTESITLLNGPKWKLMRKTMTPLFTSSK 141

Query: 100 LKSFVGIFNQNSNNVVEKLKSE 121
           LK+   I ++ + + V  LK +
Sbjct: 142 LKNMYYIMDKCAQDFVTYLKRD 163


>UniRef50_UPI0000D576F6 Cluster: PREDICTED: similar to Probable
           cytochrome P450 6a20 (CYPVIA20); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Probable cytochrome
           P450 6a20 (CYPVIA20) - Tribolium castaneum
          Length = 487

 Score =  113 bits (271), Expect = 1e-23
 Identities = 65/247 (26%), Positives = 119/247 (48%), Gaps = 7/247 (2%)

Query: 245 KTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMF 304
           K   D   K    ++ + +END   +  + F    IE  Q   N +S +EI  +      
Sbjct: 237 KETEDFFVKIVTKNIKYREENDYFRQDMMQFF---IE--QKNANTMSINEIIAQCFIFFI 291

Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364
             ++T+    +F L  L  + D+Q RV  E+  +     +  ++    EMKYL +++ E+
Sbjct: 292 AAYETSTTTLTFALYELAQNLDIQDRVRREITSVLLKHQK-YSYEAIAEMKYLNQIVDET 350

Query: 365 LRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP 424
           +R YPP   + R+  +D TI  ++  I  G   +I    +H   + Y +P+ F+PD F  
Sbjct: 351 MRKYPPFLYVVRRCTKDYTIPGEDVTIKKGIFALISILGIHHDEEIYPNPQKFDPDRFSK 410

Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQGDI 483
           EN + RH Y+Y+PF  GPR C+G+++A              ++ T++E  +   +++ D 
Sbjct: 411 ENKKMRHPYAYLPFGEGPRICIGKRFALMQIKFGLAALLEKYKFTLNEKTKVPLEIRTDT 470

Query: 484 ILKRAEG 490
           ++   +G
Sbjct: 471 LVVAPKG 477


>UniRef50_A1ZWE3 Cluster: Cytochrome P450 family protein; n=1;
           Microscilla marina ATCC 23134|Rep: Cytochrome P450
           family protein - Microscilla marina ATCC 23134
          Length = 451

 Score =  113 bits (271), Expect = 1e-23
 Identities = 63/215 (29%), Positives = 107/215 (49%), Gaps = 6/215 (2%)

Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           L +++ S    T  K+S+ ++++EV T+   GH++++A   ++  LL  + D+  +V  E
Sbjct: 232 LSMLMHSEDEDTGEKMSNQQLRDEVMTLFMAGHESSSAALGYLFWLLSQYPDIDQKVEAE 291

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           L Q  G +    TF    ++ Y  +VI E LRLYPP   + RK   D  I    Y +PAG
Sbjct: 292 LAQNLGSA--AFTFESMRQVPYSSQVINEMLRLYPPAWTVGRKAVADDEID--GYHVPAG 347

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454
           T+++I  +++HR    ++ P  F P+ +  +  +    ++Y PF  GPR C+G ++A   
Sbjct: 348 TSIMIPAYVVHRDADLWEQPHEFLPERWQTQQVKELPRFAYFPFGGGPRLCIGDQFALLE 407

Query: 455 XXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAE 489
                    R F T    P     LQ  I ++  E
Sbjct: 408 IHAVLALLKRRF-TFEHQPRHHIALQPLITMRPVE 441



 Score = 41.5 bits (93), Expect = 0.051
 Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 10/127 (7%)

Query: 54  NSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNN 113
           N + H  KA EY   K  LG GL+ + G  WR  R+M  P FH    K+ +    +    
Sbjct: 68  NKNYHKGKAFEY--MKVLLGNGLVTNEGDFWRKQRRMAQPAFH----KTKLAGLTEVMTG 121

Query: 114 VVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQR 173
           ++E+   E  + +   D ++ T    LL  A+ I  K   +S  +   A+ K+ D ++  
Sbjct: 122 LIEEFLDEWEQKYQSGDRINLTKEMNLL--ALKIVSKALFQS--EVGEAIYKIGDHLNYA 177

Query: 174 HYKFWMR 180
            Y+  MR
Sbjct: 178 LYRMMMR 184


>UniRef50_Q9BID0 Cluster: Cytochrome P450; n=27; Culicidae|Rep:
           Cytochrome P450 - Anopheles gambiae (African malaria
           mosquito)
          Length = 501

 Score =  113 bits (271), Expect = 1e-23
 Identities = 58/219 (26%), Positives = 106/219 (48%), Gaps = 8/219 (3%)

Query: 256 RDDLDFNDENDVGEKKRLAFLDLMIESS--QNGT-----NKISDHEIKEEVDTIMFEGHD 308
           +D ++F   N+V     +  L  M++    Q+GT     ++I+  ++  +       G +
Sbjct: 250 KDTVEFRQINNVQRNDFMMLLMKMLKEQMEQDGTAGDLKDRITIEDVAAQAFVFFLAGFE 309

Query: 309 TTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLY 368
           T++   SF L  L ++Q++Q +    +  +        T+    EMKY+E  I ES+R Y
Sbjct: 310 TSSTAMSFCLYELALNQELQDKARQNITDVMKQHSS-ITYEAVHEMKYIEMCINESMRKY 368

Query: 369 PPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQ 428
           PP+  + R++ +D  +   + V+  G    I  + LH  P+++ +PE F+PD F  E   
Sbjct: 369 PPITTLTRRVEKDYRVPDTDKVLQEGIMAAIPVYALHHDPEHFPNPEQFDPDRFTAEQEA 428

Query: 429 NRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467
            RH + Y+PF  GPR C+G ++             ++FR
Sbjct: 429 KRHPFVYLPFGEGPRICIGLRFGMMQARIGLVYLLKHFR 467


>UniRef50_P33270 Cluster: Cytochrome P450 6a2; n=10; Diptera|Rep:
           Cytochrome P450 6a2 - Drosophila melanogaster (Fruit
           fly)
          Length = 506

 Score =  113 bits (271), Expect = 1e-23
 Identities = 74/240 (30%), Positives = 114/240 (47%), Gaps = 16/240 (6%)

Query: 271 KRLAFLDLMIESSQNGTNKISDHEIKEEVD---------TIMFEGHDTTAAGSSFVLCLL 321
           KR  F++L+IE  Q G   + + E+ E +D              G +T+++  S+ L  L
Sbjct: 267 KRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYEL 326

Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARK-LNR 380
             +QD+Q R+ +E+  +  + +   T+     M YL +VI E+LRLY  VP + RK LN 
Sbjct: 327 AQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALND 386

Query: 381 DVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSA 440
            V    +  VI  GT V+I     HR    Y +PE F+P+ F PE    R    ++PF  
Sbjct: 387 YVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGD 446

Query: 441 GPRSCVGRKYAXXXXXXXXXXXXRNFRT----ISEIPEKEFKLQGDIILKRAEGFQMKVE 496
           GPR+C+G ++               FR      +EIP K   +   I+L    G  ++VE
Sbjct: 447 GPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPM--SIVLGTVGGIYLRVE 504


>UniRef50_UPI0000E473EA Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 511

 Score =  112 bits (269), Expect = 2e-23
 Identities = 71/234 (30%), Positives = 121/234 (51%), Gaps = 10/234 (4%)

Query: 268 GEKKRLAFLDLMIESSQN--GTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQ 325
           GE+     L  ++++SQ+  G       E+ +E  T    G +TT+   SF L +LG H 
Sbjct: 284 GEELPNDMLTNILQASQDLEGNENFGIDEMLDEFVTFFIAGQETTSNLMSFTLEMLGKHP 343

Query: 326 DVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIS 385
            V  +V DEL +  G S    +F D  ++ YL  V+ ESLR+Y P PV+ R    +V  S
Sbjct: 344 HVLQKVQDELDEKLG-SQMFISFQDMGKLDYLMLVLKESLRMYAPAPVVTRVTGTEVKAS 402

Query: 386 TKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHY-YSYIPFSAGPRS 444
           T   +IP G+ + +  F++ R  +Y++DP VF P+ F+    +++H  Y+Y PF+ G RS
Sbjct: 403 T-GLIIPKGSQLNLSPFVMGRMSEYFEDPLVFRPERFV----ESKHSPYAYFPFALGQRS 457

Query: 445 CVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           C+G+++A            + F+    +P + + L   + ++  +G +  V  R
Sbjct: 458 CIGQQFALIEARIIMAKLLQQFK-FDLVPGQNWNLSYAVTIRPDDGCRNYVSLR 510



 Score = 54.0 bits (124), Expect = 9e-06
 Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 9/176 (5%)

Query: 14  QKLVNLALGYAQTFGNVIRVWLGSKLIVFLVDADDI-EIILNSHVHIDKATEYRFFKP-- 70
           Q  ++L + + + +G V +  +  + IV   D D + EI+  + VH+     Y       
Sbjct: 70  QNKLDLLVKWQEEYGTVFKYSILHRYIVAAFDPDVVKEILSKTSVHLKPYRPYGIMAQVL 129

Query: 71  ---WLGEGLLISSG-PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTF 126
              ++G GL+  +   +W+ HR M+ P+FH   L + V  FN +++++V  L        
Sbjct: 130 GSRFMGNGLITEANHARWKVHRAMLNPSFHRKYLVTMVDTFNASADHLVNYLMERADGLQ 189

Query: 127 DV--HDYMSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMR 180
           +V  +D  +  T+DI+ +    +     D+    +  +++   + I       WM+
Sbjct: 190 EVRMYDAFNNITLDIIAKVTFNMELNIIDDPDNPFPNSILTCLNAIMTSINNPWMQ 245


>UniRef50_Q70AR8 Cluster: Putative cytochrome P450; n=1;
           Streptomyces peucetius|Rep: Putative cytochrome P450 -
           Streptomyces peucetius
          Length = 484

 Score =  112 bits (269), Expect = 2e-23
 Identities = 62/174 (35%), Positives = 95/174 (54%), Gaps = 5/174 (2%)

Query: 278 LMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ 337
           L  +  Q G  ++SD ++++EV T+   G++TTA    +   LL  H + + +V  E+ +
Sbjct: 262 LNAQDEQTG-ERMSDKQLRDEVVTMFLGGYETTALSLVWAFSLLSRHPEAERKVRSEVAE 320

Query: 338 IFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTV 397
           + GD + PA  +D   ++YL     E LRLYP V  ++R    D  I    Y IPAG+ V
Sbjct: 321 VCGDRE-PAA-SDLPRLRYLRAFYQEVLRLYPSVWTLSRSPLEDDEIG--GYHIPAGSQV 376

Query: 398 VIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
            I  +++HR P ++++PE F P+ F    T     Y+YIPFS GPR C G   A
Sbjct: 377 FISPYLMHRHPGFWENPEGFRPERFEKSATGGAPLYAYIPFSRGPRLCPGSSVA 430



 Score = 37.1 bits (82), Expect = 1.1
 Identities = 31/138 (22%), Positives = 62/138 (44%), Gaps = 5/138 (3%)

Query: 11  NLTQKLVNLALGYAQTFGNVIRVWLGSKLIVFL-VDADDIEIILNSHV--HIDKATEYRF 67
           +L + LV       + +G+++   L  K  +FL V  D I+ +L+     +         
Sbjct: 46  DLVRDLVGTFTRAWREYGDIVSFRLPGKRNLFLIVHPDHIKHVLDDRQPNYPKDPLSVGK 105

Query: 68  FKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--T 125
           F+PW+G+GL  S+G      R++  P F  + +  F     + ++++V        +  T
Sbjct: 106 FEPWVGQGLFTSNGDFHFRQRRLAQPAFKGSRISGFGPAMVEATSDLVRDWHGRATREET 165

Query: 126 FDVHDYMSGTTVDILLET 143
           FD+   M    + I+++T
Sbjct: 166 FDITPEMFRLALTIVMQT 183


>UniRef50_UPI0000DB7562 Cluster: PREDICTED: similar to Probable
           cytochrome P450 6g2 (CYPVIG2); n=1; Apis mellifera|Rep:
           PREDICTED: similar to Probable cytochrome P450 6g2
           (CYPVIG2) - Apis mellifera
          Length = 507

 Score =  111 bits (268), Expect = 3e-23
 Identities = 67/194 (34%), Positives = 98/194 (50%), Gaps = 13/194 (6%)

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAG---SSFVLC 319
           D  ++ + KR   +D ++E      N   D + K E D ++ +      AG   S  ++C
Sbjct: 266 DNREITKTKREDLIDSLMELK----NAKQDKDFKFEGDALLSQSAIFFIAGRETSISIIC 321

Query: 320 L----LGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIA 375
           L    L  H ++Q R  +E+ +     +   T+     MKYL +V+ E LR+YPP P+I 
Sbjct: 322 LTLYELAKHPEIQKRTREEINEKL--KEHGMTYEGVQSMKYLHQVVSEILRIYPPTPIID 379

Query: 376 RKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSY 435
           R    D  I   + VI  GT+V I    LH  PKY+ DP  FNPD F  EN +N   ++Y
Sbjct: 380 RVAVADYKIPGTDIVIEKGTSVFIVLTALHNDPKYHPDPLRFNPDRFSDENKENIKPFTY 439

Query: 436 IPFSAGPRSCVGRK 449
           IPF  GPR C+G +
Sbjct: 440 IPFGEGPRICIGAR 453


>UniRef50_Q0LHR9 Cluster: Cytochrome P450; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Cytochrome P450 -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 444

 Score =  111 bits (267), Expect = 4e-23
 Identities = 64/232 (27%), Positives = 115/232 (49%), Gaps = 8/232 (3%)

Query: 262 NDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLL 321
           +D+ D G+   L+ L L  ++  +GT  + + ++++E  T+   GH+TTA   S+   LL
Sbjct: 216 HDQRDHGDL--LSMLLLAQDTEGDGTG-MDNQQVRDEAITLFLAGHETTANALSWTWYLL 272

Query: 322 GIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRD 381
             H  +  R Y EL ++   + R  T  D   + Y   ++ ES+R+YPP  ++ R+   D
Sbjct: 273 SQHPAIAERWYRELDEVL--AGRIPTMDDVQNLSYTRMILAESIRMYPPAWIMGREALAD 330

Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441
             +   +Y+ PAG  + +  F++H   +++ +   FNP+ +  E    R  +SYIPF  G
Sbjct: 331 YHVG--DYIFPAGIGLTVSPFVVHHDERWFPNAYQFNPERWTAEQIAQRPKWSYIPFGGG 388

Query: 442 PRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQM 493
            R C+G ++A            + +R +  +P     LQ  I L+   G +M
Sbjct: 389 SRICIGEQFAWMEGILLLATIGQRWR-LKLMPGHPVALQPVITLRPRHGIKM 439



 Score = 54.4 bits (125), Expect = 7e-06
 Identities = 34/121 (28%), Positives = 62/121 (51%), Gaps = 3/121 (2%)

Query: 24  AQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHI-DKATEYRFFKPWLGEGLLISSGP 82
           A+ +G+V+R+  G + ++ L   DDI  +L ++  I  K+   +  K  LG GLL S G 
Sbjct: 32  AREYGDVVRLKFGPRELILLNHPDDIHAMLVTNQKILAKSVVLQRSKRLLGNGLLTSEGE 91

Query: 83  KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLE 142
           +    R+++ P FH   +  +  +    +  + E+   + G+ FDVH  M   T+ I+ +
Sbjct: 92  QHMRQRRLVQPAFHRKRIAGYAEVMANYAAEMREQW--QPGQVFDVHAEMMRLTLRIVAK 149

Query: 143 T 143
           T
Sbjct: 150 T 150


>UniRef50_A7RMN2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 414

 Score =  111 bits (267), Expect = 4e-23
 Identities = 62/172 (36%), Positives = 94/172 (54%), Gaps = 11/172 (6%)

Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFV-LCLLGIHQD--VQARV 331
           FLD+++E+     N +++  I+ EV+T MF GHDT A+G   V  CL   H+      + 
Sbjct: 251 FLDILLEAEDINGNGLNNENIRAEVNTFMFAGHDTVASGKFSVDWCLDECHRYSYFNNKF 310

Query: 332 YDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVI 391
            + L+  F   D      D   M YL   + ES+RL+ PVPVI R L+ +  I  K   +
Sbjct: 311 KNVLFLFFSCRD------DINNMNYLSMCMKESMRLFSPVPVIGRTLDEEYVIDGKR--V 362

Query: 392 PAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPR 443
           P GT V++  + +HR P  ++ P++FNP  F  +  + R  Y++IPFS GPR
Sbjct: 363 PEGTFVLVCIYAVHRNPHVWEKPQMFNPRRFETDTVEGRSAYAFIPFSGGPR 414



 Score = 82.6 bits (195), Expect = 2e-14
 Identities = 50/193 (25%), Positives = 98/193 (50%), Gaps = 5/193 (2%)

Query: 25  QTFGNVIRVWLGS-KLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPK 83
           + F    RVW G  +  + L   D ++ +L+ +   ++   Y+F  P+LG+GL +  G K
Sbjct: 42  ERFKTAYRVWFGPLRSALVLCHPDTVKPVLSKNAPKERFF-YKFLFPFLGDGLGLQEGAK 100

Query: 84  WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV---GKTFDVHDYMSGTTVDIL 140
           W + RK++ P FH +IL+ +V IF +++  +VEK        G+  ++   +S  T+D +
Sbjct: 101 WWNTRKLVTPAFHFDILRRYVPIFQESAKILVEKWSQACGPSGRKVELFQDISLMTLDSV 160

Query: 141 LETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGI 200
           L+ A   S   Q E    Y  A+  +   +  R    +   + +++LT    +  K   +
Sbjct: 161 LKCAFSYSSNCQTEGHDKYIKAINGIAKALLDRLLNPFYHFDWLYRLTPARSKFMKYCDL 220

Query: 201 IHGLTNKVIKNKK 213
           IH  +++VI++++
Sbjct: 221 IHQKSDEVIESRR 233


>UniRef50_UPI0000D577ED Cluster: PREDICTED: similar to Cytochrome
           P450 6g1 (CYPVIG1) (Cyp6-like protein); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Cytochrome P450 6g1
           (CYPVIG1) (Cyp6-like protein) - Tribolium castaneum
          Length = 523

 Score =  111 bits (266), Expect = 6e-23
 Identities = 55/192 (28%), Positives = 94/192 (48%), Gaps = 1/192 (0%)

Query: 259 LDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVL 318
           LD  D+  V  K R   +D++++   +  N I    +  +       G +TT++   F L
Sbjct: 279 LDIMDKRSVSNKSRNDLIDILLQMKNDNRNFIEGDILVSQALMFFVAGFETTSSTMGFAL 338

Query: 319 CLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKL 378
                + D+Q ++ +E+  I  D      +    EM+YL+  + E LR YP VP + RK 
Sbjct: 339 YEFARNPDIQDKIRNEIKDI-SDKYGDIKYDSLKEMEYLDMCVKEVLRKYPVVPFLDRKC 397

Query: 379 NRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPF 438
           N   TI   N  I   T + I +  LH  P+Y+ + ++F+P+ F   N      ++Y+PF
Sbjct: 398 NTTYTIPDTNVTIDKDTPIFIPSLALHYDPQYFPNADIFDPERFSSNNKTGIDSFAYLPF 457

Query: 439 SAGPRSCVGRKY 450
             GPR+C+G ++
Sbjct: 458 GEGPRNCIGARF 469


>UniRef50_Q0LFI0 Cluster: Cytochrome P450; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Cytochrome P450 -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 457

 Score =  111 bits (266), Expect = 6e-23
 Identities = 63/225 (28%), Positives = 114/225 (50%), Gaps = 7/225 (3%)

Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           LD+++E+    T  ++SD +I++EV TI   GH+TTA   +F   LL  H +++  +  E
Sbjct: 238 LDMLLEAQDAETGERMSDEQIRDEVLTIFAAGHETTANTLTFGWYLLSEHCEIRQNLQTE 297

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIA-RKLNRDVTISTKNYVIPA 393
           L Q+     R  +  D  ++ Y  +V  E++RLYP  P+   R++ +   +    Y +P 
Sbjct: 298 LDQVL--QGRAPSVNDLPQLPYTLQVFKEAMRLYPAAPITGPRRVTKPTQLG--GYDLPL 353

Query: 394 GTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXX 453
            + V++    LH  P ++++P  F+P  F P   Q RH+ +++PF AGPR C+G   A  
Sbjct: 354 NSQVIVSITNLHLHPAFWENPLQFDPSRFAPNANQPRHHLAFMPFGAGPRKCIGNNLAEM 413

Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
                     +++    + P  + K +  I ++   G  M ++ R
Sbjct: 414 EGALLLACVAQHYNPQLQ-PGHQVKPEMAITMRAKAGMPMLLKRR 457



 Score = 35.1 bits (77), Expect = 4.4
 Identities = 25/119 (21%), Positives = 55/119 (46%), Gaps = 3/119 (2%)

Query: 28  GNVIRVWLGSKLIVFLVDADDIEIILNSHVH-IDKATEYRFFKPWLGEGLLISSGPK-WR 85
           G+++R  +GS+++  + + D  + +L  H     K       +   G GL+ +  P+ W 
Sbjct: 45  GDIVRYQIGSRIVHVVSNPDYAQYVLVEHQRDFPKVGGNGGLQIIAGNGLISNPSPESWL 104

Query: 86  SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKS-EVGKTFDVHDYMSGTTVDILLET 143
             R+M+ P FH   L +     +     ++++ ++       D+   M   T+DI+++T
Sbjct: 105 IQRRMMQPMFHRKRLAAMGEKIDGAGARMIQRWQALPDAAPIDMDHEMLQVTLDIIMQT 163


>UniRef50_A5FJE6 Cluster: Cytochrome P450; n=1; Flavobacterium
           johnsoniae UW101|Rep: Cytochrome P450 - Flavobacterium
           johnsoniae UW101
          Length = 448

 Score =  111 bits (266), Expect = 6e-23
 Identities = 57/177 (32%), Positives = 101/177 (57%), Gaps = 6/177 (3%)

Query: 276 LDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           L++++E+    T + +S  ++ +E+  +   GH+TTA   +F L LLG + +VQ ++++E
Sbjct: 233 LNMLLETRYEDTGESMSVEQLIDEIKVLFIAGHETTANALTFTLHLLGRNPEVQQKIFEE 292

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           + +I   +D         +M Y   V+ ES+RLYPP  +  R+   D +++  ++ I   
Sbjct: 293 IIEIESQTDN--VIEQLQKMTYTNAVLNESMRLYPPAWITDRQNLEDDSLA--HFKIKKN 348

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           T + +  + LHR PKY+K+P+ F P+ FL +  +    Y Y PF AGPR C+G  +A
Sbjct: 349 TLIGVSFYELHRNPKYWKNPDEFIPERFLGDQKKESMQYFY-PFGAGPRMCIGTGFA 404



 Score = 42.3 bits (95), Expect = 0.029
 Identities = 33/129 (25%), Positives = 55/129 (42%), Gaps = 5/129 (3%)

Query: 23  YAQTFGNVIRVWLG-SKLIVFLVDADDIEIIL--NSHVHIDKATEYRFFKPWLGEGLLIS 79
           Y    G+   + +G SK I+   D +  + IL  N   +     +  +   +LG+GLL S
Sbjct: 36  YFDKLGDSFSIRIGFSKYIILSRDNEIAQYILVKNQKNYHKSKFQSVYLSKYLGKGLLTS 95

Query: 80  SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDI 139
            G  W   R++I P FH   +   V   N      +E L  E  K  D+   MS    ++
Sbjct: 96  DGDFWLKQRRLIQPAFHKQKMNQLVDNMNAVIALELENLIEE--KPIDLFPVMSNLAFNV 153

Query: 140 LLETAMGIS 148
           + ++   +S
Sbjct: 154 VAKSLFQLS 162


>UniRef50_Q6PW74 Cluster: Cytochrome P450 CYP331A1; n=1; Capitella
           capitata|Rep: Cytochrome P450 CYP331A1 - Capitella
           capitata
          Length = 549

 Score =  110 bits (265), Expect = 7e-23
 Identities = 107/475 (22%), Positives = 211/475 (44%), Gaps = 39/475 (8%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGE----GLLI 78
           ++Q +G+    + G   I+   D D ++ I   + +     +Y   +P   E     + +
Sbjct: 63  WSQEYGSTFGYFEGPTPILVSSDLDLLKEIFIKNFNKFHGRKYVPVQPDPAEDKGCSMFM 122

Query: 79  SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTT 136
           + G +W+  R +  PTF    LK    + N+ S  +++KL++    G    +   +   T
Sbjct: 123 AQGQRWKRLRTITNPTFTAAKLKHSTELMNRKSRTLLKKLEAIATKGDKCRILPLLQDLT 182

Query: 137 VDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMR-SEIVFKL---TSFFK 192
           +D++ E+A GI    Q+ +G + +++++K     +     F+    E+ F +    +FF 
Sbjct: 183 LDVIGESAFGIEVNAQEIAG-NPSLSMLKRNREQNTLRKSFYATLPELRFTIYHCLAFFA 241

Query: 193 QQTKL--LGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDT 250
           +   +    I+  +  KV++ +K     N    +      E T+H G +           
Sbjct: 242 KFVSVPRFQILESM-GKVLEMRKIQPQRNPPDLMQLMVDAEATNHHGSL----------- 289

Query: 251 VFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTN------KISDHEIKEEVDTIMF 304
             + + DD D +D++D  +      +D+ I  +    +      K++  EIK +    + 
Sbjct: 290 --EIFADDDDDDDDDDYAKASPDESIDIQISEADRERHARTRKKKLTADEIKSQGFLFLL 347

Query: 305 EGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILES 364
            G++TT+   +     L  + D Q  +Y+E+  I  D D   T+     + YL+ V+ E+
Sbjct: 348 AGYETTSNTLACCSHALANNPDKQQLLYEEVNSIIQD-DEELTYEKVKALPYLDMVLRET 406

Query: 365 LRLYP-PVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY--KDPEVFNPDN 421
           LR+YP    V+ R+     TI+  + V+P    +    + +H     +   DP++F P+ 
Sbjct: 407 LRMYPIGSQVVTRRCVETCTIN--DLVVPRDMAIHANVWDVHYNANIWGATDPKIFEPER 464

Query: 422 FLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKE 476
           FLP+    RH  +++PF AGPR+C+G ++A            + FR +S    KE
Sbjct: 465 FLPDRKARRHPLAWLPFGAGPRNCIGLRFALLEAQIVLAKLIKKFRIVSCDQTKE 519


>UniRef50_UPI0000D5650B Cluster: PREDICTED: similar to Cytochrome
           P450 6a2 (CYPVIA2) (P450-B1); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Cytochrome P450 6a2
           (CYPVIA2) (P450-B1) - Tribolium castaneum
          Length = 485

 Score =  110 bits (264), Expect = 1e-22
 Identities = 62/220 (28%), Positives = 108/220 (49%), Gaps = 8/220 (3%)

Query: 257 DDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSF 316
           D + + +END     R  F+ L+IE  +   N+++  EI  +       G +T++A  +F
Sbjct: 250 DSVKYREENDY---VRSDFMQLLIEMKKQ--NQLTIEEIAAQCFVFFIAGFETSSATLTF 304

Query: 317 VLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIAR 376
            L  L  +Q++Q    DE   I  +     T+    ++K+L++V+ E+LR YPP+  + R
Sbjct: 305 ALYELAKNQNLQNVARDE---ILANCPNEITYDSLADLKFLDQVVDETLRKYPPLLYVTR 361

Query: 377 KLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYI 436
           +  ++  I  ++ VI  GT V I    LH   ++Y  PE F P+ F       RH Y+++
Sbjct: 362 QCVKNYKIPDEDVVIEKGTLVAIPISALHSDEEFYPKPETFEPERFSKTEKSLRHPYTFL 421

Query: 437 PFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKE 476
           PF  GPR C+G+++             +N++       KE
Sbjct: 422 PFGEGPRMCIGKRFGLLEVKLALTCLLKNYKFSVNCKTKE 461



 Score = 40.3 bits (90), Expect = 0.12
 Identities = 41/172 (23%), Positives = 76/172 (44%), Gaps = 18/172 (10%)

Query: 34  WLGSKLIVFLVDADDIE-IILNSHVH-IDKATEYRFFKPWLGEGLLISSGPKWRSHRKMI 91
           + G   I  +VD D I+ I+     H +D+   +      L   L    G KW++ R+ +
Sbjct: 75  YFGVSPICLIVDPDLIKNIVTRDFEHFVDRGVYFNEKDDPLSGHLANLDGQKWKNMRRKL 134

Query: 92  APTFHINILKSFVGIFNQNSNNVVEKLKS---EVGKTFDVHDYMSGTTVDILLETAMGIS 148
            PTF  +  K+   I      N++EK+KS      K  ++++     +++++   A G+ 
Sbjct: 135 NPTFSASKTKNMFPIVKFCVENMMEKVKSCYENAHKCCNINEVFPAFSINVICSCAFGL- 193

Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGI 200
              Q+E+    A A     + +    YK+     +V  L +FF +  K +GI
Sbjct: 194 ---QEENALFKAYA----DECVSWTKYKY-----LVQILATFFDKTAKRMGI 233


>UniRef50_A2XB72 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. indica (Rice)
          Length = 531

 Score =  109 bits (263), Expect = 1e-22
 Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 9/224 (4%)

Query: 281 ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG 340
           E+S     K++  E+ +E  T  F GH+TTA   S+ L +L  H + QA V +E+ ++ G
Sbjct: 308 EASAGAERKLTTRELVDECKTFFFGGHETTALALSWTLLMLAAHPEWQAAVREEVVEVAG 367

Query: 341 DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTI----STKNYVIPAGTT 396
            S  P   A   ++  +  V+ E LRLYPP P + R+  +DV +      K  VIP GT 
Sbjct: 368 RSG-PLDAAALGKLTKMGCVLSEVLRLYPPSPNVQRQALQDVVVVAGDGEKKVVIPKGTN 426

Query: 397 VVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQN--RHYYSYIPFSAGPRSCVGRKYAXX 453
           + I    +HR  + + ++   F P+ F+ E  Q   RH   Y+PF  G R CVGR     
Sbjct: 427 MWIDVVAMHRDGELWGEEASEFRPERFMREGVQGGCRHRMGYVPFGFGGRICVGRNLTAM 486

Query: 454 XXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEP 497
                     R F  +   PE     +  + L+ + G Q+++ P
Sbjct: 487 ELRVVLAMVLRRF-AVEVAPEYRHAPRIMLSLRPSHGIQLRLTP 529



 Score = 51.6 bits (118), Expect = 5e-05
 Identities = 33/140 (23%), Positives = 65/140 (46%), Gaps = 6/140 (4%)

Query: 23  YAQTFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHI--DKATEYRFFK-PWLGEGLLIS 79
           + + FG V   WLG++  +++ D + ++      +     K   +R  + P  G GL+++
Sbjct: 85  WRRAFGKVFVYWLGTEPFLYVADPEFLKAATAGALGKLWGKPDVFRRDRMPMFGRGLVMA 144

Query: 80  SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKT-FDVHDYMSGTT 136
            G +W  HR +IAP F    L   +G+  + +  ++ +    V  G++  DV   +    
Sbjct: 145 EGDEWARHRHIIAPAFSATNLNDMIGVMEETTAKMLGEWGDMVASGRSCVDVEKGVVRNA 204

Query: 137 VDILLETAMGISRKTQDESG 156
            +I+   + GIS    D +G
Sbjct: 205 AEIIARASFGISADDDDATG 224


>UniRef50_Q234S0 Cluster: Cytochrome P450 family protein; n=2;
           Tetrahymena thermophila SB210|Rep: Cytochrome P450
           family protein - Tetrahymena thermophila SB210
          Length = 522

 Score =  109 bits (263), Expect = 1e-22
 Identities = 101/398 (25%), Positives = 173/398 (43%), Gaps = 32/398 (8%)

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT-FDVHDY 131
           G+GL+++    W   R  ++ +FH N LK+ V I  + +   +  L S+ GKT   + + 
Sbjct: 119 GQGLVVAEEKVWTRQRNFLSNSFHFNALKNRVPIIKEITKEFLSTLPSD-GKTPITIIEE 177

Query: 132 MSGTTVDILLETAMGISRKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFF 191
           +   T +++++T  G + K    +G   ++ + K+        + +   S   F     F
Sbjct: 178 LQNITSEVVIQTFFGENLKGMTVNGLQPSVEISKIIG----DGFSYKANSFAYFLKLMVF 233

Query: 192 KQQTKLLGIIHGLTNKVIKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTV 251
            Q+ K   +++    K    + E Y     +GI+   L E      E L + +K + +  
Sbjct: 234 GQE-KASRVLNTTFEKNFLKRVENY-NQFIEGIVDKRLSEL-----EKLTDTSK-VDENF 285

Query: 252 FKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTA 311
              Y   L++  +    ++    + D  I         I   EI  +  T  F G DTTA
Sbjct: 286 LNLYL--LEYIKQQKALKENPKIYADYEI---------IPKREIVHQFTTFFFAGMDTTA 334

Query: 312 AGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPV 371
             +   L +L  H ++Q ++  E+  +    D      D  +++Y      ESLR+YP  
Sbjct: 335 NQTGICLWVLAQHPELQQKIRAEIDSVIQTFD-DLKHEDLNKLEYFNAFFKESLRVYPTA 393

Query: 372 P-VIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQ--PKYYKDPEVFNPDNFLPENTQ 428
           P VI R   RD  +   ++ IP G  V   T   + Q  P   KD + FNPD FL +N  
Sbjct: 394 PQVIPRVSARDHMVD--DFPIPKGAFVSNLTIQYNEQKFPLLCKDIDTFNPDRFLDKNII 451

Query: 429 NRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNF 466
             H+ S+IP+SAGPR+C+G+  A            +N+
Sbjct: 452 QDHF-SFIPYSAGPRNCIGQHLALIEAKIMIAYILKNY 488


>UniRef50_Q179B9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 506

 Score =  109 bits (263), Expect = 1e-22
 Identities = 66/247 (26%), Positives = 127/247 (51%), Gaps = 8/247 (3%)

Query: 260 DFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLC 319
           D + E +  + K L  +D ++  S +G  + +D +I++ V  ++    DTT+  ++    
Sbjct: 262 DVDTEEEYNKPKIL--VDQLLGVSHDG-RQFNDIQIRDNVYAVITGATDTTSLATAHACL 318

Query: 320 LLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLN 379
            L  + D+Q R++ EL ++F  +    T  +  ++ YL+  I E  R    VP +AR+  
Sbjct: 319 FLSFYPDIQERLHAELAEVFPGNIADYTPENIKKLTYLDMFINEVQRHCTVVPYVARENT 378

Query: 380 RDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPF 438
            ++ I      +P G   ++  + +H++P  +  D E F+P+NF  E  ++RH  +++P+
Sbjct: 379 AEIEID--GVKVPPGNIFIMSLYAMHKRPDIWGPDAEKFDPENFTEERIKDRHPAAFLPY 436

Query: 439 SAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           SAG ++C+G +YA            RNF   S+I  ++ + + D+ LK    FQ  V+ +
Sbjct: 437 SAGSKNCLGWRYAIFGMKLIMIHLVRNFHFSSKIKHEDMQFRHDLTLKLP--FQHLVQLK 494

Query: 499 KRVPTNV 505
           KR P  +
Sbjct: 495 KRNPGKI 501



 Score = 55.2 bits (127), Expect = 4e-06
 Identities = 49/235 (20%), Positives = 102/235 (43%), Gaps = 13/235 (5%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           ++  W G K+ +     D +  IL+S   +++   YRF      +G+  +  P W+ +RK
Sbjct: 69  ILTAWAGPKMFLITSHPDIVHQILSSPDCLERPFLYRF--AGFTQGIFTAKLPVWKDNRK 126

Query: 90  MIAPTFHINILKSFVGIFNQNSNNVVEK-LKSEVGKTFDVHDYMSGTTVDILLETAMGIS 148
            +  TF+  I+  FV  F +    + +  L+   G+T ++  Y +   +++   T +G  
Sbjct: 127 RLNSTFNQRIVHGFVPYFVKCCEKMTKSLLECADGETVNIQKYTAVCALEMAAGTTLGGD 186

Query: 149 RKTQDESGFDYAMAVMKMCDIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKV 208
              Q +   ++   +    +   +R       S++++++T  +K+  +   II     K+
Sbjct: 187 VLQQGDGKEEFKRGLDLAFNGASRRMVTVPFYSDLIYQMTHHYKELMEGRRIICDFFTKL 246

Query: 209 IKNKKETYLENKAKGIIPPTLEEFTHHSGEILANNAKTLSDTVFKGYRDDLDFND 263
           +  +K+ +L + +K     T EE+         N  K L D +     D   FND
Sbjct: 247 LIERKK-FLLDHSKNTDVDTEEEY---------NKPKILVDQLLGVSHDGRQFND 291


>UniRef50_Q0UKV8 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 536

 Score =  109 bits (263), Expect = 1e-22
 Identities = 79/247 (31%), Positives = 124/247 (50%), Gaps = 18/247 (7%)

Query: 267 VGEKKRLAFLD----LMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
           VG+KK  A L+    L I S    +N  SD  + +++ T +  GH+TT++  ++   LL 
Sbjct: 287 VGQKKANAKLESKESLDILSIMLRSNNFSDSNLVDQLLTFLAAGHETTSSALTWSGYLLS 346

Query: 323 IHQDVQARVYDELYQIFGD----SDRPATFADTLE-MKYLERVILESLRLYPPVPVIARK 377
            H DV+A++ +E+Y+   D    SD     A  LE M YL  V  E LR+YP VP+ AR 
Sbjct: 347 THPDVKAKLRNEIYKHIPDPQALSDPAMDVAGLLEGMPYLNAVCNEVLRVYPTVPITARY 406

Query: 378 LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPEN---TQN---R 430
             RD  I+     IP GT + I  + ++R PK +  D E F P+ ++ EN   T N    
Sbjct: 407 AVRDTNIA--GQYIPKGTVLFIPPWAINRNPKLWGPDSEKFVPERWIDENGRTTMNGGAD 464

Query: 431 HYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEG 490
             Y+++ F  GPR+C+G ++A             +F      P+++    G I  K   G
Sbjct: 465 SNYAFLTFLHGPRACIGERFARAELRALVAALVGSFDFQMAYPDEKVIAAGTITSKPLNG 524

Query: 491 FQMKVEP 497
            ++K++P
Sbjct: 525 MRLKLQP 531



 Score = 48.0 bits (109), Expect = 6e-04
 Identities = 30/120 (25%), Positives = 57/120 (47%), Gaps = 5/120 (4%)

Query: 32  RVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYR-FFKPWLGEGLLISSGPKWRSHRKM 90
           R +  S  ++    A   +I+++    ++K    R F + +LG+GLL++ G + + HRK 
Sbjct: 100 RGFFHSNKVIVTSTAALADILVHKSYDMEKPPPVRTFLRKFLGDGLLMTEGDEHKHHRKN 159

Query: 91  IAPTFHINILKSFVGIFNQNS----NNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMG 146
           I P FH   +K    IF   S    N +   ++    +  ++  Y +  T+DI+    +G
Sbjct: 160 IMPAFHFRHIKELYPIFWSKSIEFCNAMGRAIQDNDDRVLEIGHYATQVTLDIIGLAGLG 219


>UniRef50_A1DAX0 Cluster: Cytochrome P450; n=5; Trichocomaceae|Rep:
           Cytochrome P450 - Neosartorya fischeri (strain ATCC 1020
           / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
           ATCC 1020 / DSM 3700 / NRRL 181))
          Length = 547

 Score =  109 bits (263), Expect = 1e-22
 Identities = 67/216 (31%), Positives = 112/216 (51%), Gaps = 13/216 (6%)

Query: 291 SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFAD 350
           +D E+ +++ T +  GH+TTA+  ++   LL +H DVQ R+  E+ +     + P T++D
Sbjct: 328 TDDELVDQMLTFLAAGHETTASALTWACYLLTLHPDVQERLRTEIREHIPSGNHPITWSD 387

Query: 351 TLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKY 410
              M  L  V  E LRLYP VP+  R+  RD TI+ K+  +P GT ++I  + ++R P++
Sbjct: 388 LESMPLLNGVCQEVLRLYPTVPITIREAVRDTTIAGKH--VPKGTRILICPYAINRSPEF 445

Query: 411 YKD-PEVFNPDNFL--PENTQN--RH------YYSYIPFSAGPRSCVGRKYAXXXXXXXX 459
           + D  E F P+ ++   +N Q    H       Y+ I F  G RSC+G+ +A        
Sbjct: 446 WGDNGEEFLPERWIDPDKNGQKVVNHNGGASTNYAQITFLHGQRSCIGKDFARAELRCAV 505

Query: 460 XXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKV 495
                 FR   + P++E  + G +  K  EG  +K+
Sbjct: 506 AGVVGRFRFEMQDPKQEIHIAGAVTTKPVEGMHLKM 541



 Score = 35.5 bits (78), Expect = 3.3
 Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 9/67 (13%)

Query: 65  YRFFKPW---------LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV 115
           Y F KPW         +G GL++S G   +  RK + P F+I  ++S   +  + +   +
Sbjct: 125 YDFEKPWRAREFLARIIGFGLILSEGAAHKKQRKALTPAFNIKNIRSLYSLMWEKTGLFL 184

Query: 116 EKLKSEV 122
           ++L+ E+
Sbjct: 185 DELEKEI 191


>UniRef50_Q70AR1 Cluster: Putative cytochrome P450; n=1;
           Streptomyces peucetius|Rep: Putative cytochrome P450 -
           Streptomyces peucetius
          Length = 448

 Score =  109 bits (262), Expect = 2e-22
 Identities = 58/181 (32%), Positives = 102/181 (56%), Gaps = 6/181 (3%)

Query: 268 GEKKRLAFLDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQD 326
           G  +    L +++ +  + T + +SD E+++E+ TI+F G +TTA+  S+    L  H +
Sbjct: 222 GTSEHNDLLSVLLGARDSETGEYLSDTEVRDELSTILFAGAETTASTLSWTFYQLAEHPE 281

Query: 327 VQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST 386
           V+A +  E+  + GD  RP +  D  +++ + RV+ E +RL+  V ++ R+    V +  
Sbjct: 282 VEAELVAEIKDVVGD--RPVSIEDVPKLEAVRRVLDEVIRLHG-VTMLMRRTTAPVELG- 337

Query: 387 KNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446
             +++P GT V    + +HR P  Y DP+ F+PD +LPE   +    +YIPF AG R C+
Sbjct: 338 -GHLLPVGTEVGFSLYAMHRDPTLYDDPDRFDPDRWLPERRGDITRQAYIPFGAGNRKCI 396

Query: 447 G 447
           G
Sbjct: 397 G 397



 Score = 41.5 bits (93), Expect = 0.051
 Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 3/117 (2%)

Query: 28  GNVIRVWLGSKLIVFLVDADDI-EIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRS 86
           G+++RV LG+  +     A+ I E+ +      +K   +   +P  G+GL  ++G   R 
Sbjct: 40  GDLVRVNLGTMPMYVATSAELIHEVTVRQARSFEKGRFFDRLRPLAGDGLATANGEVHRK 99

Query: 87  HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLET 143
           HR++I P FH   +  +    + N+  + +   +  G+  ++   M+   ++ L  T
Sbjct: 100 HRRLIQPMFHPGRITMYAETMSSNALALADSWTA--GQEVEMEQAMAQFAIETLATT 154


>UniRef50_Q7QCC3 Cluster: ENSANGP00000012179; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000012179 - Anopheles gambiae
           str. PEST
          Length = 504

 Score =  109 bits (262), Expect = 2e-22
 Identities = 62/234 (26%), Positives = 116/234 (49%), Gaps = 9/234 (3%)

Query: 270 KKRLAFLDLMIES--SQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDV 327
           +K   F+D +++   +       SD EI + + T++  G++T+A   +    LL +H  +
Sbjct: 275 RKPQIFIDQLMKMPLTDPSARHFSDEEISDHIYTMIVAGNETSATQLAHTCLLLAMHPHI 334

Query: 328 QARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK 387
           Q + Y+E+  +    D+  T     ++ YLE V+ E++RL P  P++ R+   ++ +   
Sbjct: 335 QTKAYEEVAGLVFSPDQEITIELMKDLHYLECVLKEAMRLMPVAPIVGRQSRAEIVLD-- 392

Query: 388 NYVIPAGTTVVIGTFMLHRQPKYY-KDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 446
            + IP G+  +   + LHR+   +    + F P  FL +    RH Y+++PFS GPR C+
Sbjct: 393 GHRIPQGSVFLFHFYALHRRKDVWGPTADEFEPGRFLADG--GRHPYAHLPFSGGPRGCI 450

Query: 447 GRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500
           G +YA            RN+  ++++  ++ + Q  I L  A  F   V  R+R
Sbjct: 451 GYRYAMMSLKTLLAQLLRNYELMTDLRYEDIRYQYQISLNLA--FPHAVRLRRR 502



 Score = 71.7 bits (168), Expect = 4e-11
 Identities = 45/182 (24%), Positives = 96/182 (52%), Gaps = 7/182 (3%)

Query: 36  GSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRKMIAPTF 95
           GS+L + L   + ++ +L       K   Y+  +  L  GLL +    W+ HRK +  TF
Sbjct: 75  GSQLAIGLTHPELVQKVLTHPDCQAKPDLYKVVR--LPNGLLAAKYDVWKVHRKTLNSTF 132

Query: 96  HINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGISRKTQD 153
           +  IL+SFV IFN  +  +V +L   +  G   ++ +Y+S  T++++  T++G   K  +
Sbjct: 133 NARILESFVPIFNDCTQRLVGRLDRYARSGDRCNILEYISACTLEMISRTSLG--GKVLE 190

Query: 154 ESGFDYAMAVMKMC-DIIHQRHYKFWMRSEIVFKLTSFFKQQTKLLGIIHGLTNKVIKNK 212
             G +  +A +++    I  R +  ++  + +++ T+ ++++ + + I    T+K+I+ K
Sbjct: 191 REGAEQFIANLEVALKTIGVRIFNIFLHIDFIYQFTALYRKEMRAINICQQFTSKIIQAK 250

Query: 213 KE 214
           +E
Sbjct: 251 RE 252


>UniRef50_Q93VK5 Cluster: At1g31800/68069_m00159; n=12;
           Magnoliophyta|Rep: At1g31800/68069_m00159 - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 595

 Score =  109 bits (261), Expect = 2e-22
 Identities = 64/215 (29%), Positives = 104/215 (48%), Gaps = 9/215 (4%)

Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349
           +S  ++++++ T++  GH+T+AA  ++   LL     V A++ +E+  + GD  R  T  
Sbjct: 362 VSSKQLRDDLMTMLIAGHETSAAVLTWTFYLLTTEPSVVAKLQEEVDSVIGD--RFPTIQ 419

Query: 350 DTLEMKYLERVILESLRLYPPVPV-IARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQP 408
           D  ++KY  RV+ ESLRLYP  PV I R ++ D+      Y I  G  + I  + LHR P
Sbjct: 420 DMKKLKYTTRVMNESLRLYPQPPVLIRRSIDNDI---LGEYPIKRGEDIFISVWNLHRSP 476

Query: 409 KYYKDPEVFNPDNFL---PENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRN 465
            ++ D E FNP+ +    P   +    +SY+PF  GPR C+G  +A            R 
Sbjct: 477 LHWDDAEKFNPERWPLDGPNPNETNQNFSYLPFGGGPRKCIGDMFASFENVVAIAMLIRR 536

Query: 466 FRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRKR 500
           F           K+     +   EG ++ V  R +
Sbjct: 537 FNFQIAPGAPPVKMTTGATIHTTEGLKLTVTKRTK 571



 Score = 49.2 bits (112), Expect = 3e-04
 Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 3/118 (2%)

Query: 26  TFGNVIRVWLGSKLIVFLVDADDIEIILNSHVHI-DKATEYRFFKPWLGEGLLISSGPKW 84
           T+G + R+  G K  + + D    + IL  +     K          +G+GL+ + G  W
Sbjct: 138 TYGGIFRLTFGPKSFLIVSDPSIAKHILKDNAKAYSKGILAEILDFVMGKGLIPADGEIW 197

Query: 85  RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDIL 140
           R  R+ I P  H   + + + +F + S+ + +KL +    G+  ++    S  T+DI+
Sbjct: 198 RRRRRAIVPALHQKYVAAMISLFGEASDRLCQKLDAAALKGEEVEMESLFSRLTLDII 255


>UniRef50_Q2Y711 Cluster: Cytochrome P450; n=1; Nitrosospira
           multiformis ATCC 25196|Rep: Cytochrome P450 -
           Nitrosospira multiformis (strain ATCC 25196 / NCIMB
           11849)
          Length = 448

 Score =  107 bits (258), Expect = 5e-22
 Identities = 87/318 (27%), Positives = 151/318 (47%), Gaps = 22/318 (6%)

Query: 194 QTKLLGIIHGLTNKVIKNKK-ETYLENKAKGIIPPTLEEFTHHSGEILANN------AKT 246
           Q  L G +  LT +VI      T + +K + I P +LE    ++   +AN         T
Sbjct: 140 QINLSGEMMRLTLEVITQTMFSTSVLDKIERIAP-SLEILLRYAARTIANPLTLPVYVPT 198

Query: 247 LSDTVFK---GYRDDLDFN--DENDVGEKKRLAFLDLMIESSQNGTN-KISDHEIKEEVD 300
            ++  FK   G  DD+ +   D+       +   LD++++   + +  K++D ++++EV 
Sbjct: 199 PANRKFKQALGIIDDVIYGIIDQRRAAPSDQNDLLDMLLKVRDDDSGEKMTDRQVRDEVI 258

Query: 301 TIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERV 360
           TI   GH+TTA   S+ L LL  H  V  R+ +EL ++     +     D  ++ Y   V
Sbjct: 259 TIFSAGHETTANLLSWTLYLLVRHPGVLTRLREELDRVL--QGKIPNAEDLQQLVYTRAV 316

Query: 361 ILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPD 420
           + ES+RL PP   + RK+++D  +    Y + AG   +   F LH    ++  PE F+P+
Sbjct: 317 LSESMRLRPPASFLLRKVSKDTEVD--GYFLKAGKLAIFSIFNLHHHADFWPQPEQFDPE 374

Query: 421 NFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQ 480
            FL   +QNR  YS+IPF  G R C+G  +A            ++   +  +  KE +++
Sbjct: 375 RFL--LSQNRR-YSFIPFGTGERICIGSHFALMESQLLLCMIIQHC-DLQLLDSKEVEME 430

Query: 481 GDIILKRAEGFQMKVEPR 498
             I L+   G  +++  R
Sbjct: 431 MAITLRPKGGIPVRINWR 448


>UniRef50_Q9NB69 Cluster: Cytochrome P450 monooxygenase; n=2;
           Tribolium castaneum|Rep: Cytochrome P450 monooxygenase -
           Tribolium castaneum (Red flour beetle)
          Length = 126

 Score =  107 bits (258), Expect = 5e-22
 Identities = 51/122 (41%), Positives = 73/122 (59%), Gaps = 1/122 (0%)

Query: 315 SFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVI 374
           +F L +L  H  VQ  +  E+  + GD+ +   + D  E+KY+ERVI E LRLYP V  I
Sbjct: 6   NFALMVLANHPTVQEEIVQEMKDVLGDTKKKPVYNDLQELKYMERVIKEVLRLYPSVHYI 65

Query: 375 ARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYS 434
           +R+L  D+ ++T  Y +  GT + +  + LH  P  Y +PE F+PD FLPEN   RH Y+
Sbjct: 66  SRELGEDM-VTTTGYKLRKGTILQLHIYDLHYNPVIYPEPEKFDPDRFLPENCDKRHPYA 124

Query: 435 YI 436
           YI
Sbjct: 125 YI 126


>UniRef50_A6WEH8 Cluster: Cytochrome P450; n=1; Kineococcus
           radiotolerans SRS30216|Rep: Cytochrome P450 -
           Kineococcus radiotolerans SRS30216
          Length = 429

 Score =  107 bits (257), Expect = 7e-22
 Identities = 61/162 (37%), Positives = 90/162 (55%), Gaps = 6/162 (3%)

Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349
           + D ++++E+ T +  GH+T A+  ++ L LL     V ARV+ EL    G   R   + 
Sbjct: 224 MDDRQVRDELVTFVVAGHETVASSLTWTLDLLARAPSVLARVHAELAGALGG--REPGWD 281

Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409
           D  ++  L  V+ ESLRLYPP  V+ R+   D  ++     +PAGT V++ T+ LHR P 
Sbjct: 282 DLGKLPLLRAVVDESLRLYPPAWVVTRQALADDVVA--GVAVPAGTLVIVCTWGLHRDPA 339

Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
            ++ PE F PD FL  +       SY+PF AGPR C+GR  A
Sbjct: 340 LWEAPEEFRPDRFL--DAPRPAAGSYVPFGAGPRLCIGRDLA 379



 Score = 38.3 bits (85), Expect = 0.47
 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 2/71 (2%)

Query: 28 GNVIRVWLGSKLIVFLVDADDIEIILNSHVH-IDKAT-EYRFFKPWLGEGLLISSGPKWR 85
          G V  + L    ++ L D D +  +L  +     KAT +Y       G GLL   G  W+
Sbjct: 24 GPVAAIPLPRTPVLVLADPDGVRRVLVENARGYGKATIQYSALATVTGPGLLAGDGEVWK 83

Query: 86 SHRKMIAPTFH 96
           HR+ + P FH
Sbjct: 84 QHRRTVQPAFH 94


>UniRef50_A7T1A2 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 523

 Score =  107 bits (257), Expect = 7e-22
 Identities = 57/181 (31%), Positives = 100/181 (55%), Gaps = 3/181 (1%)

Query: 272 RLAFLDLMIES-SQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQAR 330
           R  F+DLM+ + + +G+ K+SD EI  +  T +  GH+T++   S     L ++ +VQ R
Sbjct: 297 RKDFVDLMLSAVNPDGSRKLSDPEIIAQSVTFLLAGHETSSNTLSATAYYLALNPEVQER 356

Query: 331 VYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYV 390
           +  E+      +   +      +++YL+ V+ E LR++PP   I R+  +   I+     
Sbjct: 357 LRLEIRMAAETNSEKSPQELANDLEYLDCVVNEVLRIHPPAHTINRECAQACVIN--GIT 414

Query: 391 IPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKY 450
           IPAG  V I  + LH  P  + +P+ F+P+ F     ++RH + +IPF AGPR+C+G ++
Sbjct: 415 IPAGMDVTIPIYSLHHDPDAWPEPDKFDPERFRGPAKESRHPFQFIPFGAGPRNCIGMRF 474

Query: 451 A 451
           A
Sbjct: 475 A 475


>UniRef50_UPI0000E48EAF Cluster: PREDICTED: similar to cytochrome
           P450 CYP3A24; n=2; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to cytochrome P450 CYP3A24 -
           Strongylocentrotus purpuratus
          Length = 412

 Score =  107 bits (256), Expect = 9e-22
 Identities = 48/172 (27%), Positives = 91/172 (52%), Gaps = 3/172 (1%)

Query: 280 IESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIF 339
           ++   +   ++++ E+  +       G++TT     ++L LL  H DVQ ++ +E+  + 
Sbjct: 195 LQKKSSSKIRLNESEVISQALIFFLAGYETTNTTCGYMLYLLATHPDVQDKLVNEIDDVA 254

Query: 340 GDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVI 399
            +++    +    +M YLE++  E+ R+YPP  +  R  N    I+   + +P G  + I
Sbjct: 255 PEAE-DVGYQSISKMPYLEQIFCETERIYPPALMTDRVCNEPFDIN--GFTVPKGMRIFI 311

Query: 400 GTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
             F +H  P  + DPE ++PD F  EN +  H  +++PF  GPR+CVG ++A
Sbjct: 312 PIFTIHHDPNLWPDPETYDPDRFSKENREKHHPCAWMPFGTGPRNCVGMRFA 363


>UniRef50_UPI0000D5745C Cluster: PREDICTED: similar to Probable
           cytochrome P450 28a5 (CYPXXVIIIA5); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Probable cytochrome
           P450 28a5 (CYPXXVIIIA5) - Tribolium castaneum
          Length = 740

 Score =  107 bits (256), Expect = 9e-22
 Identities = 58/194 (29%), Positives = 102/194 (52%), Gaps = 5/194 (2%)

Query: 278 LMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELY 336
           L I S    TN+  +D ++         +G +T++   SFVL  L I+ DVQ+++  E+ 
Sbjct: 270 LHIISQLKKTNQDFTDVDVTAHAAGFFADGSETSSIVMSFVLFQLSINPDVQSKLRAEVT 329

Query: 337 QIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKN----YVIP 392
           + F +++    +    ++ YLE VI E+LR+ PP+  + +   +  T + K      VI 
Sbjct: 330 EAFNNNNNNMPYEVVQDLPYLEAVIQETLRIQPPIHSLQKLCTKSFTWTLKETNKPLVIE 389

Query: 393 AGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 452
            GT ++I T  L   P++++DPE F P+ FL EN +N    +++PF  GPR+C+G+++  
Sbjct: 390 EGTPIIIPTHALQSDPQHFEDPESFQPERFLGENRENIKKCTHMPFGEGPRACLGQRFGL 449

Query: 453 XXXXXXXXXXXRNF 466
                      +NF
Sbjct: 450 LQIKVGLAYIVKNF 463


>UniRef50_Q3EBT7 Cluster: Uncharacterized protein At2g26170.1; n=7;
           core eudicotyledons|Rep: Uncharacterized protein
           At2g26170.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 522

 Score =  107 bits (256), Expect = 9e-22
 Identities = 77/232 (33%), Positives = 116/232 (50%), Gaps = 12/232 (5%)

Query: 275 FLDLMI---ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARV 331
           FL L++   ES     N  +   I       +  G  TTA   S VL L+  H DV+ R+
Sbjct: 294 FLSLILKARESDPFAKNIFTSDYISAVTYEHLLAGSATTAFTLSSVLYLVSGHLDVEKRL 353

Query: 332 YDELYQIFGDSDRPATFADTL-EMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYV 390
             E+   FG+ D   T  D   +  YL++VI E++R Y   P++AR+  ++V I    Y+
Sbjct: 354 LQEI-DGFGNRDLIPTAHDLQHKFPYLDQVIKEAMRFYMVSPLVARETAKEVEIG--GYL 410

Query: 391 IPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP--ENTQNRHYYSYIPFSAGPRSCVGR 448
           +P GT V +   +L + PK + +PE F P+ F P  E  ++RH Y++IPF  GPR+CVG+
Sbjct: 411 LPKGTWVWLALGVLAKDPKNFPEPEKFKPERFDPNGEEEKHRHPYAFIPFGIGPRACVGQ 470

Query: 449 KYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGD--IILKRAEGFQMKVEPR 498
           ++A            RN+       E E  LQ D  IIL    G +++   R
Sbjct: 471 RFALQEIKLTLLHLYRNY-IFRHSLEMEIPLQLDYGIILSFKNGVKLRTIKR 521


>UniRef50_Q29AT3 Cluster: GA11819-PA; n=6; Diptera|Rep: GA11819-PA -
           Drosophila pseudoobscura (Fruit fly)
          Length = 513

 Score =  107 bits (256), Expect = 9e-22
 Identities = 61/214 (28%), Positives = 110/214 (51%), Gaps = 5/214 (2%)

Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349
           IS   I  +       G +TT + ++FVL  L  + ++  R+  E+ +    +D   T+ 
Sbjct: 303 ISLESITAQAFIFYIAGQETTGSTAAFVLFELAQYPELLERLQTEVDETLAKNDGHITYD 362

Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409
              +M++L+  + ESLR YP +P++ R+  +D T+   ++VIP GT VVI  + +H   +
Sbjct: 363 ALQKMEFLDLCVQESLRKYPGLPMLNRECTQDYTVPDTDHVIPKGTPVVISLYGIHHDAE 422

Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRT- 468
           Y+ +PE ++PD +  EN +N    +++PF  GPR C+ ++              +NF   
Sbjct: 423 YFPEPETYDPDRYSEEN-RNFSPTAFMPFGEGPRICIAQRMGLLNAKLAIINVLKNFNVE 481

Query: 469 ISEIPEKEFKLQGDIILKRAEGFQMKVEPRKRVP 502
           +    + EF+  G  +L +  G  +KV   KR+P
Sbjct: 482 VMSKRQLEFENSGIALLPK-NG--VKVRLSKRLP 512


>UniRef50_Q9VG82 Cluster: Probable cytochrome P450 9f2; n=26;
           Endopterygota|Rep: Probable cytochrome P450 9f2 -
           Drosophila melanogaster (Fruit fly)
          Length = 516

 Score =  107 bits (256), Expect = 9e-22
 Identities = 54/180 (30%), Positives = 96/180 (53%), Gaps = 3/180 (1%)

Query: 291 SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSD-RPATFA 349
           SD +I  +     F G +T+A    F    L  +QDVQ R+Y+E+ Q+  D + +  T+ 
Sbjct: 303 SDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYE 362

Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVT--ISTKNYVIPAGTTVVIGTFMLHRQ 407
             + MKYL++V+ E LR +P    + R+ N+D+T  +  +   +  G  + + T   HR 
Sbjct: 363 AIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRD 422

Query: 408 PKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR 467
           PKY+++P  F+P+ F  EN ++   ++Y PF  G R+C+G ++A            +++R
Sbjct: 423 PKYFENPMKFDPERFSDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYR 482



 Score = 36.7 bits (81), Expect = 1.4
 Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 4/79 (5%)

Query: 73  GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT----FDV 128
           G  L      +W+  R  ++P F  + ++    + NQ +   V+ LK +  +      D+
Sbjct: 123 GSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDM 182

Query: 129 HDYMSGTTVDILLETAMGI 147
            DY +  T D++  TA G+
Sbjct: 183 KDYCTRFTNDVIASTAFGL 201


>UniRef50_Q27664 Cluster: Cytochrome P450 6B2; n=46;
           Obtectomera|Rep: Cytochrome P450 6B2 - Helicoverpa
           armigera (Cotton bollworm) (Heliothis armigera)
          Length = 504

 Score =  107 bits (256), Expect = 9e-22
 Identities = 69/241 (28%), Positives = 117/241 (48%), Gaps = 14/241 (5%)

Query: 275 FLDLMIESSQNGT-------NKISDHEIKEEV---DTIMF--EGHDTTAAGSSFVLCLLG 322
           F+DL++E  Q G        N +S  EI E V      +F   G++T+A   +++   L 
Sbjct: 263 FMDLILELRQMGEITSNKYGNNMSTLEITESVMCAQAFVFYIAGYETSATTMAYLTYQLA 322

Query: 323 IHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDV 382
           ++ D+Q ++  E+ +    +    T+    +MKYL +V  E+LR+Y  V  + RK  RD 
Sbjct: 323 LNPDIQNKLIAEIDEAIKANGGKVTYDTVKDMKYLNKVFDETLRMYSIVEPLQRKAIRDY 382

Query: 383 TISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGP 442
            +   + VI   T V+I    +H  PKYY +P+ FNP+ F  E    RH  +Y+PF  G 
Sbjct: 383 KLPGTDVVIEKDTVVLISPRGIHYDPKYYDNPKQFNPERFFAEEVGKRHPCAYLPFGLGQ 442

Query: 443 RSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKLQG-DIILKRAEGFQMKVEPRKR 500
           R+C+G ++               FR   S+  ++  +++    I+    G ++ + PRK 
Sbjct: 443 RNCIGMRFGRLQSLLCITKLLSKFRLEPSKNTDRNLQVEPYRFIIGPKGGIRLNIVPRKD 502

Query: 501 V 501
           V
Sbjct: 503 V 503



 Score = 48.0 bits (109), Expect = 6e-04
 Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 2/124 (1%)

Query: 30  VIRVWLGSKLIVFLVDADDIEIILNSHVHIDKATEYRFFKPWLGEGLLISSGPKWRSHRK 89
           VI ++  +   + + D + I+ I+     +       F K  LG+ L  + G  WR+ R 
Sbjct: 71  VIGIYRMTSPCLLVRDLEVIKHIMIKDFEVFSDRGLEFSKEGLGQNLFHADGDTWRTLRN 130

Query: 90  MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGI 147
              P F    LK+   + N+ ++N ++ +  E  K   F++H  +   T+  +   A G+
Sbjct: 131 RFTPIFTSGKLKNMFYLMNEGADNFIDHVSKECEKHQEFEIHTLLQTYTMSTISSCAFGV 190

Query: 148 SRKT 151
           S  T
Sbjct: 191 SYDT 194


>UniRef50_UPI00015B60B4 Cluster: PREDICTED: similar to cytochrome
           P450; n=3; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 533

 Score =  106 bits (255), Expect = 1e-21
 Identities = 60/189 (31%), Positives = 99/189 (52%), Gaps = 2/189 (1%)

Query: 263 DENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLG 322
           D+  + E K L   D    ++ +   KIS  E   +       G +TT++  ++ L  L 
Sbjct: 285 DKGSLDEDKDLKQKDNNNSANGSALGKISLSEAIGQAFIFYLAGFETTSSTITYCLYELA 344

Query: 323 IHQDVQARVYDELYQIFGDSDRPATFAD-TLEMKYLERVILESLRLYPPVPVIARKLNRD 381
           ++ ++Q +V  E+ + F   D   T+   + +MKYL  V LE+LR +P +P + R+   D
Sbjct: 345 LNPEIQEKVQAEIDE-FSKRDGGITYEIMSNDMKYLHMVFLETLRKHPSIPFLNRECIED 403

Query: 382 VTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAG 441
             I   N+ I  GT ++I    +HR P  + DPE F+P  F  EN  +R  Y+Y+PF  G
Sbjct: 404 CDIPNTNFRIEKGTKLLICMNAMHRDPDIFPDPEKFDPFRFTKENIASRQPYTYLPFGDG 463

Query: 442 PRSCVGRKY 450
           PR+C+G ++
Sbjct: 464 PRACIGIRF 472


>UniRef50_UPI0000E473D8 Cluster: PREDICTED: hypothetical protein;
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 507

 Score =  106 bits (255), Expect = 1e-21
 Identities = 58/178 (32%), Positives = 94/178 (52%), Gaps = 5/178 (2%)

Query: 276 LDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDEL 335
           L L I +   G        + +E  T+   G +TT+   +F +  LG H DV  ++  E+
Sbjct: 286 LILDIANDLEGDKDFGMENMLDEFVTLFIAGQETTSNLLAFTILQLGRHPDVAKKLQAEV 345

Query: 336 YQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGT 395
            ++ G       + D  +++Y+ RV+ E+LRLY PV    R     V  +     IPA  
Sbjct: 346 DEVLGQK-HTIQYEDLAKLEYMMRVLKETLRLYSPVGGTTRLTAHPVKYN--GITIPAKA 402

Query: 396 TVVIGTFMLHRQPKYYKDPEVFNPDNFLP--ENTQNRHYYSYIPFSAGPRSCVGRKYA 451
           TV + ++++ R  +Y+ DP +FNPD F P  + +  RH Y+Y PFS G RSC+G+++A
Sbjct: 403 TVTVMSYVMSRMEEYFDDPLLFNPDRFKPSEDGSLPRHLYAYFPFSMGQRSCIGQQFA 460



 Score = 39.5 bits (88), Expect = 0.20
 Identities = 34/147 (23%), Positives = 61/147 (41%), Gaps = 11/147 (7%)

Query: 42  FLVDADDI--EIILNSHVHIDKATEYRFFKP-----WLGEGLLIS-SGPKWRSHRKMIAP 93
           F   A +I  E++LNS  HI     Y  F+      ++G GL+      KW   R ++ P
Sbjct: 92  FFASAPEIVKELLLNSR-HIKPQEIYHGFQKLYGERFMGHGLVSEVDHEKWFHRRAIMNP 150

Query: 94  TFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVH--DYMSGTTVDILLETAMGISRKT 151
            F    L S +  +N  S  + +KLK +     +V   D ++  T+D++ + A  +    
Sbjct: 151 AFRRKYLISLMEEYNSGSEALCQKLKEKADGKIEVPMLDELNKVTLDVIAKIAFSMDTNA 210

Query: 152 QDESGFDYAMAVMKMCDIIHQRHYKFW 178
             +    +  A+      +   H + W
Sbjct: 211 IGDPDCPFPAAITAALQGLQSLHERPW 237


>UniRef50_UPI0000E46433 Cluster: PREDICTED: similar to Cytochrome
           P450, family 2, subfamily u, polypeptide 1; n=2;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           Cytochrome P450, family 2, subfamily u, polypeptide 1 -
           Strongylocentrotus purpuratus
          Length = 487

 Score =  106 bits (255), Expect = 1e-21
 Identities = 59/224 (26%), Positives = 110/224 (49%), Gaps = 8/224 (3%)

Query: 281 ESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFG 340
           E    G +++   E+   V  +M  G DTT+    + + ++  + D+Q +V++E+  + G
Sbjct: 261 EDDDVGEDRLKTKEVWRLVYDLMLAGSDTTSNTLKWAVLVMAYYPDIQKKVHNEIDCVLG 320

Query: 341 DSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIG 400
           +  R     D   M Y++  I+E LR+ P +P+    L  + T+  + Y IP G  ++  
Sbjct: 321 E--RSPCLQDKKSMSYIQATIMEVLRVRPVLPLALEHLTSETTV-LRGYTIPKGAILIPN 377

Query: 401 TFMLHRQPKYYKDPEVFNPDNFLPENTQN--RHYYSYIPFSAGPRSCVGRKYAXXXXXXX 458
            +  H  P+Y+ +PEVFNP  FL E+ Q+     ++++PFS GPR C+G + A       
Sbjct: 378 VWSCHHNPEYWDNPEVFNPGRFLSEDNQSLGEEPHAFLPFSFGPRKCLGDQLAKNELFLI 437

Query: 459 XXXXXRNFR---TISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
                + F       + PE   +     ++ R    +++++PRK
Sbjct: 438 FAKIMQRFHIDFAPGDRPESFDEGFDKGLILRPNNMKVRLQPRK 481


>UniRef50_Q82QD5 Cluster: Putative cytochrome P450 /
           NADPH-ferrihemoprotein reductase; n=1; Streptomyces
           avermitilis|Rep: Putative cytochrome P450 /
           NADPH-ferrihemoprotein reductase - Streptomyces
           avermitilis
          Length = 1073

 Score =  106 bits (255), Expect = 1e-21
 Identities = 62/225 (27%), Positives = 117/225 (52%), Gaps = 5/225 (2%)

Query: 276 LDLMIESSQNGTNK-ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           L LM+E++   T K + D  ++++V T +  GH+TT+   SF    L  +  + A+ Y E
Sbjct: 243 LGLMLEATDPETGKGLDDDNVRDQVVTFLIAGHETTSGLLSFATYSLMRNPHILAQAYAE 302

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           + ++    D    +   ++M  + R++ E+LRL+ P+P+I +    D  I    Y +  G
Sbjct: 303 VDRLL-PGDTVPDYDTIMQMDVIPRILEETLRLWAPIPMIGKSPLEDTVIGGC-YGLKKG 360

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXX 454
             V I    LH  PK ++ PE F+ + +LPEN  N H ++Y PF  G R+C+GR++A   
Sbjct: 361 ARVNILEGPLHTHPKAWERPEEFDINRWLPENRVNHHPHAYKPFGNGVRACIGRQFALTE 420

Query: 455 XXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQMKVEPRK 499
                    + F+  ++  + +  ++ + + ++  GF++ V  R+
Sbjct: 421 ARLALALVLQKFK-FADTDDYKMDVK-EALTRKPGGFELNVRARQ 463


>UniRef50_Q2J4I2 Cluster: Cytochrome P450; n=2; Frankia|Rep:
           Cytochrome P450 - Frankia sp. (strain CcI3)
          Length = 489

 Score =  106 bits (255), Expect = 1e-21
 Identities = 65/228 (28%), Positives = 115/228 (50%), Gaps = 15/228 (6%)

Query: 276 LDLMIESSQNGTN-KISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           L L++ +    T   + D ++++E  T++  GH+TTA   ++   LLG   +V A +  E
Sbjct: 258 LSLLLTARDADTGASMDDSQVRDEALTLLLAGHETTANALTWTFHLLGRDPEVLATLQAE 317

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAG 394
           L ++ G  +R  T  D  ++ Y   VI E++RLYPPV  + R L  D  ++   Y +PAG
Sbjct: 318 LDRVLG--ERRPTIDDLPQLPYTNAVISEAMRLYPPVWAMGRHLVEDRDVA--GYRLPAG 373

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQN---------RHYYSYIPFSAGPRSC 445
           +T+V   +++HR  +++  PE+F+P  +   +T +         R  ++Y PF AGPR C
Sbjct: 374 STLVFSQWVVHRDERWWPRPELFDPIRWTGPDTADEPADAGPKMRPRFAYFPFGAGPRQC 433

Query: 446 VGRKYAXXXXXXXXXXXXRNFRTISEIPEKEFKLQGDIILKRAEGFQM 493
           +G  +A            R + + + +P      Q  + L+  +G  M
Sbjct: 434 IGNTFAITEGVLALAAIARRW-SFTPVPGLPVTPQPLVTLRPKDGLPM 480



 Score = 40.3 bits (90), Expect = 0.12
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 72  LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDY 131
           LG+GLL S+G   R  R+++ P FH   +  +   F   ++   +  +   G+  DVH  
Sbjct: 113 LGQGLLTSAGDTHRQQRRLLQPLFHKQRIAGYADAFAAIADKTADGWRD--GQRLDVHTE 170

Query: 132 MSGTTVDILLETAMGI 147
           M+  T+ I+  T   +
Sbjct: 171 MTEMTLAIVARTLFDV 186


>UniRef50_Q1ZXL9 Cluster: Cytochrome P450 family protein; n=2;
           Dictyostelium discoideum|Rep: Cytochrome P450 family
           protein - Dictyostelium discoideum AX4
          Length = 601

 Score =  106 bits (255), Expect = 1e-21
 Identities = 64/207 (30%), Positives = 106/207 (51%), Gaps = 17/207 (8%)

Query: 288 NKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQ-----IFGDS 342
           + + + +I   ++T +  GH+T+A   +F+  LL  H +VQ  +Y+ L +     I  D+
Sbjct: 375 DNVKEKDIIGNINTFLLAGHETSANLLTFIFYLLSTHNNVQNDLYNHLIENQKKKINKDN 434

Query: 343 DRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTIST--------KNYVIPAG 394
                  D   +++L+ VI E+LRL+PP P+I R    D  + +         N  IP+ 
Sbjct: 435 KFTEEDEDYQSIEFLDWVIYETLRLFPPAPMIGRTSKNDDILKSGNNNNNNNNNISIPSE 494

Query: 395 TTVVIGTFMLHRQPKYYKDPEVFNPDNFLP-ENTQNRHYYSYIPFSAGPRSCVGRKYAXX 453
           T ++I  + +HR PK +KDP +FNP  +   EN  NR    +IPFS+G R CVG+K++  
Sbjct: 495 TLILISVYAIHRDPKLWKDPNIFNPYRWKNIENINNRS--DFIPFSSGGRVCVGQKFSIV 552

Query: 454 XXXXXXXXXXRNFR-TISEIPEKEFKL 479
                      NF  + + +  K FK+
Sbjct: 553 EARIIISKLILNFELSFNNLKSKPFKI 579


>UniRef50_Q9V4U7 Cluster: Probable cytochrome P450 6a14; n=10;
           Schizophora|Rep: Probable cytochrome P450 6a14 -
           Drosophila melanogaster (Fruit fly)
          Length = 509

 Score =  106 bits (255), Expect = 1e-21
 Identities = 56/194 (28%), Positives = 99/194 (51%), Gaps = 3/194 (1%)

Query: 306 GHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTL-EMKYLERVILES 364
           G +T+++  S  L  L +  D+Q R+ +E+  +  + D      D L +M YL++V+ E+
Sbjct: 314 GFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSET 373

Query: 365 LRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLP 424
           LR +P +P + R+  +D  I   + V+  G   +I    +H  P+ Y +PE F+P  F P
Sbjct: 374 LRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDP 433

Query: 425 ENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFR-TISEIPEKEFKL-QGD 482
           E  +NRH  +Y+PF  GPR+C+G ++             R F+ ++S   +      +  
Sbjct: 434 EEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKS 493

Query: 483 IILKRAEGFQMKVE 496
            +L   +G  +KVE
Sbjct: 494 FLLTTNDGIYLKVE 507


>UniRef50_UPI0000DB6D9C Cluster: PREDICTED: similar to Cytochrome
           P450 6a2 (CYPVIA2) (P450-B1); n=1; Apis mellifera|Rep:
           PREDICTED: similar to Cytochrome P450 6a2 (CYPVIA2)
           (P450-B1) - Apis mellifera
          Length = 427

 Score =  106 bits (254), Expect = 2e-21
 Identities = 58/180 (32%), Positives = 91/180 (50%), Gaps = 4/180 (2%)

Query: 275 FLDLMIESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDE 334
           F+ LMIE  Q G  KI +  +     +   +G +T++   +F+ C L IHQDVQ ++  E
Sbjct: 200 FIQLMIEMEQTG-EKIDEEIVAAHAVSFYLDGVETSSVTLNFIGCQLAIHQDVQEKLRKE 258

Query: 335 LYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTK---NYVI 391
           +           TF    +M Y+ +VI ES R +  +  + +    +  +      NY  
Sbjct: 259 VRSTLEKHGGVLTFEALKDMTYMNQVISESQRYFSALGFLGKICTDEFELQGSDGLNYRA 318

Query: 392 PAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 451
             GT ++I    LH+ PKY+ +PE+F+P+ F  EN Q     ++IPF  GPR CVG + A
Sbjct: 319 KPGTELLIPICGLHKDPKYWDNPEIFDPERFSDENKQRIEKMAFIPFGEGPRICVGMRMA 378


>UniRef50_UPI0000D56516 Cluster: PREDICTED: similar to Probable
           cytochrome P450 6a20 (CYPVIA20); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Probable cytochrome
           P450 6a20 (CYPVIA20) - Tribolium castaneum
          Length = 442

 Score =  106 bits (254), Expect = 2e-21
 Identities = 56/204 (27%), Positives = 97/204 (47%)

Query: 244 AKTLSDTVFKGYRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIM 303
           AK+  D      R+ ++F ++ +      L  L  +     +   + S  E+  +     
Sbjct: 239 AKSAGDFFINIVRNTVEFREKTNTIRNDFLQLLINLKNDESDDWGQFSIEEVAAQCFIFF 298

Query: 304 FEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILE 363
             G +T+A   SF L  +  +  V  ++ DE+ ++    +         EM YL +V+ E
Sbjct: 299 LAGFETSATTMSFALYEIAANPHVYEQIMDEMRRVLDKYNGEMCHDAIKEMTYLGQVVDE 358

Query: 364 SLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFL 423
           +LR++ P   ++R   +D  +   N V+  G  V+I    +H  P++Y +PE F P+ F 
Sbjct: 359 TLRIHSPAYAVSRTCTQDYHVPETNIVLKKGFQVLIPIRGIHSDPEFYPEPEKFKPERFH 418

Query: 424 PENTQNRHYYSYIPFSAGPRSCVG 447
           P+N QN   YSY+PF  GPR C+G
Sbjct: 419 PDNRQNIEPYSYLPFGEGPRICIG 442



 Score = 36.3 bits (80), Expect = 1.9
 Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 2/74 (2%)

Query: 76  LLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMS 133
           LL  +G KW+  R  + PTF    +K    IF +    +   L+  ++   +FDV +  S
Sbjct: 119 LLSLNGEKWKRLRSKLTPTFTAGKIKMVFKIFVECGKIIEHTLEHHAQNRTSFDVKEMFS 178

Query: 134 GTTVDILLETAMGI 147
             + D+++  A G+
Sbjct: 179 SYSTDVIVNCAFGV 192


>UniRef50_Q0LK65 Cluster: Cytochrome P450; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Cytochrome P450 -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 454

 Score =  106 bits (254), Expect = 2e-21
 Identities = 63/205 (30%), Positives = 101/205 (49%), Gaps = 7/205 (3%)

Query: 295 IKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEM 354
           +++E  T+ F GH+TTA   SF+   L  + DV  R+  E+  + GD+    T     ++
Sbjct: 256 LRDEAITVFFAGHETTARTLSFLWYALANNPDVAERMQAEIDSVLGDA--APTLDHLKQL 313

Query: 355 KYLERVILESLRLYPPVPVIARK-LNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKD 413
            Y  +VI E+LRLYP  P+ AR  +  D     K   +P G+ + I  ++ HR P ++  
Sbjct: 314 PYTLQVIKETLRLYPAAPMYARDAVASDEFAGIK---VPVGSRMTIMPYLTHRHPDFWDK 370

Query: 414 PEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTISEIP 473
           P  F+PD +LPE    RH ++Y PF+AG R C+G  ++            R+F  +  +P
Sbjct: 371 PLRFDPDRWLPEREALRHPFAYHPFAAGQRICIGNNFSLFESHVVVAMLARHF-ALRTVP 429

Query: 474 EKEFKLQGDIILKRAEGFQMKVEPR 498
               ++  D  L    G  M +  R
Sbjct: 430 NHTPQVWMDGTLGSRNGLPMFITQR 454



 Score = 49.2 bits (112), Expect = 3e-04
 Identities = 32/125 (25%), Positives = 64/125 (51%), Gaps = 4/125 (3%)

Query: 27  FGNVIRVWLGSKLIVFLVDADDIEIIL--NSHVHIDKATEYRFFKPWLGEGLLISSGPKW 84
           +G++  + LGSK +  +V  D +  ++      +  KA+     K  LG+GL+ S+G  W
Sbjct: 39  YGDLAHLQLGSKDMFLVVHPDHVRRVMVEQRDTYSKKASYEGVRKLLLGDGLVASTGSLW 98

Query: 85  RSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK--LKSEVGKTFDVHDYMSGTTVDILLE 142
           R  RK++AP F    +++++ I  ++     E+    ++ G+  D+   MS  T  I+L+
Sbjct: 99  RRQRKLMAPFFTPRAIETYLPIIVEDGAWFRERWSAAAKQGEPLDILTEMSVLTASIILK 158

Query: 143 TAMGI 147
           +   +
Sbjct: 159 SMFSL 163


>UniRef50_A1HDJ4 Cluster: Cytochrome P450; n=4;
           Burkholderiaceae|Rep: Cytochrome P450 - Ralstonia
           pickettii 12J
          Length = 1079

 Score =  106 bits (254), Expect = 2e-21
 Identities = 64/209 (30%), Positives = 103/209 (49%), Gaps = 4/209 (1%)

Query: 290 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFA 349
           + D  I+ +V T +  GH+TT+   +F L +L  H  V A+ Y E+ ++    D    +A
Sbjct: 267 LDDTNIRFQVITFLIAGHETTSGLLTFALYMLLRHPAVLAQAYAEVDRVL-PGDTVPQYA 325

Query: 350 DTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPK 409
              ++  +ERV+ E+LRL+P  P        D  I  + Y I     VV     LHR P 
Sbjct: 326 HLAQLDVIERVLKETLRLWPTAPSFGVAPYEDTRIGGR-YAIRKDQRVVTVLLALHRDPA 384

Query: 410 YYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXXXXXRNFRTI 469
            +  PE F+ D FLPEN    H ++Y PF  G R+C+GR++A            + F  +
Sbjct: 385 VWDRPEAFDIDRFLPENEAKLHPHAYKPFGNGERACIGRQFALTEAKLALAVILQRF-AL 443

Query: 470 SEIPEKEFKLQGDIILKRAEGFQMKVEPR 498
           S+  +  F ++  + LK  +GF+++   R
Sbjct: 444 SDPYDYGFHIKETLTLK-PDGFRLRARLR 471


>UniRef50_Q5W1K8 Cluster: Cytochrome P450 CYP6AX1 protein; n=2;
           Hemiptera|Rep: Cytochrome P450 CYP6AX1 protein -
           Nilaparvata lugens (Brown planthopper)
          Length = 514

 Score =  106 bits (254), Expect = 2e-21
 Identities = 59/199 (29%), Positives = 101/199 (50%), Gaps = 3/199 (1%)

Query: 255 YRDDLDFNDENDVGEKKRLAFLDLMIESSQNGTNKISDHEIKEEVDTIMF--EGHDTTAA 312
           YR+D      + +     L  +D  +E   N  + +   +     +T +F   G +TTA 
Sbjct: 265 YREDNKVERNDFIQILMNLKKIDENMEIDPNNESHVILDDKLLAANTFIFFIAGFETTAT 324

Query: 313 GSSFVLCLLGIHQDVQARVYDELYQIFGDSDRPATFADTLEMKYLERVILESLRLYPPVP 372
             +F +  L ++Q++Q ++  E+   F +      +  T +M YL+RVI E+LR YP   
Sbjct: 325 TLTFSMYELAVNQEIQDKLRQEVQTTF-EKYGAINYDSTKDMDYLDRVISETLRKYPIAG 383

Query: 373 VIARKLNRDVTISTKNYVIPAGTTVVIGTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHY 432
            + R+  +   +      +  G  VVI  + +H  PKYY DP+ F+P+ F PEN ++R  
Sbjct: 384 SLIRRCTKAWQVPGAKGKLEVGDRVVIPVYPIHHDPKYYPDPQKFDPERFTPENKRSRPP 443

Query: 433 YSYIPFSAGPRSCVGRKYA 451
            +Y+PF  GPR C+G ++A
Sbjct: 444 CTYMPFGDGPRICIGARFA 462



 Score = 40.3 bits (90), Expect = 0.12
 Identities = 29/119 (24%), Positives = 55/119 (46%), Gaps = 5/119 (4%)

Query: 34  WLGSKLIVFLVDADDI--EIILNSHVHI-DKATEYRFFKPWLGEGLLISSGPKWRSHRKM 90
           WL ++  + +V   ++  +I++   VH  D+ T        L   LL  +G +W++ R+ 
Sbjct: 81  WLANRSPLLMVKDPELIQQILVKDFVHFYDRGTTVDMKLDPLNANLLNMTGQRWKALRQK 140

Query: 91  IAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETAMGI 147
           + P F    LK     FN+  +++   +  KS   +  DV + MS    D++   A G+
Sbjct: 141 LTPAFSSGKLKLMSPQFNECVDDLCGLIDEKSNKKELIDVQESMSKLATDVIGSCAFGL 199


>UniRef50_Q16FQ1 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 505

 Score =  106 bits (254), Expect = 2e-21
 Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 4/168 (2%)

Query: 280 IESSQNGTNKISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQDVQARVYDELYQIF 339
           +E+S N + K++  E+  +       G +T+++  SF L  L  + +VQ +V  E+  + 
Sbjct: 288 VETSTN-SKKLTIGEVAAQAHVFFLAGFETSSSTMSFCLYELAKNPEVQRKVQSEIDSVT 346

Query: 340 GDSDRPATFADTLEMKYLERVILESLRLYPPVPVIARKLNRDVTISTKNYVIPAGTTVVI 399
              D   T+    EM+YLE  I E+LR YPPVPV+ R+  +D  +   +  I  GT V++
Sbjct: 347 ALHDGKLTYDSINEMRYLECCIDETLRKYPPVPVLNRECTKDYKVPDSDITIEKGTAVIL 406

Query: 400 GTFMLHRQPKYYKDPEVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 447
               +H  P+YY DP  F P+ FL  + + +    Y PF  GPR C+G
Sbjct: 407 QISAMHHDPQYYPDPLRFVPERFLDPDMKGK---PYAPFGDGPRICIG 451


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.320    0.137    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 563,526,749
Number of Sequences: 1657284
Number of extensions: 24165219
Number of successful extensions: 64211
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1285
Number of HSP's successfully gapped in prelim test: 1008
Number of HSP's that attempted gapping in prelim test: 58611
Number of HSP's gapped (non-prelim): 3387
length of query: 507
length of database: 575,637,011
effective HSP length: 104
effective length of query: 403
effective length of database: 403,279,475
effective search space: 162521628425
effective search space used: 162521628425
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 75 (34.3 bits)

- SilkBase 1999-2023 -