Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001003-TA|BGIBMGA001003-PA|IPR001128|Cytochrome P450,
IPR002401|E-class P450, group I, IPR000923|Blue (type 1) copper domain
(420 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 210 9e-54
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 210 9e-54
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 210 9e-54
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 210 9e-54
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 167 5e-41
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 160 1e-38
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 160 1e-38
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 159 2e-38
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 159 2e-38
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 159 2e-38
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 159 2e-38
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 159 2e-38
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 159 2e-38
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 159 2e-38
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 159 2e-38
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 159 2e-38
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 159 2e-38
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 159 2e-38
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 159 2e-38
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 159 2e-38
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 159 2e-38
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 159 2e-38
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 159 2e-38
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 155 4e-37
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 155 4e-37
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 155 4e-37
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 155 4e-37
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 155 4e-37
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 155 4e-37
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 155 4e-37
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 155 4e-37
AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 155 4e-37
AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 155 4e-37
AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 155 4e-37
AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 155 4e-37
AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 155 4e-37
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 155 4e-37
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 155 4e-37
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 154 5e-37
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 154 5e-37
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 153 8e-37
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 149 1e-35
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 149 2e-35
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 149 2e-35
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 149 2e-35
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 149 2e-35
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 149 2e-35
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 148 3e-35
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 148 3e-35
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 148 3e-35
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 148 3e-35
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 148 3e-35
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 146 1e-34
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 146 2e-34
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 145 3e-34
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 145 3e-34
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 145 3e-34
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 145 3e-34
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 145 3e-34
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 145 3e-34
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 145 3e-34
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 144 4e-34
AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, famil... 144 5e-34
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 144 5e-34
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 142 3e-33
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 142 3e-33
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 142 3e-33
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 142 3e-33
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 133 1e-30
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 133 1e-30
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 129 2e-29
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 129 2e-29
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 129 2e-29
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 128 3e-29
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 128 3e-29
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 128 3e-29
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 128 3e-29
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 128 3e-29
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 128 3e-29
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 128 3e-29
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 128 3e-29
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 128 3e-29
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 128 3e-29
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 128 4e-29
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 128 4e-29
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 128 4e-29
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 126 1e-28
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 126 1e-28
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 126 2e-28
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 126 2e-28
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 126 2e-28
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 126 2e-28
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 126 2e-28
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 126 2e-28
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 126 2e-28
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 126 2e-28
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 126 2e-28
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 126 2e-28
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 124 4e-28
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 124 4e-28
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 124 4e-28
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 124 4e-28
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 122 3e-27
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 122 3e-27
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 118 5e-26
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 99 3e-20
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 99 3e-20
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 97 8e-20
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 97 8e-20
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 97 8e-20
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 95 3e-19
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 95 3e-19
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 95 4e-19
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 95 4e-19
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 95 4e-19
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 95 4e-19
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 95 4e-19
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 95 4e-19
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 95 4e-19
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 94 1e-18
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 94 1e-18
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 94 1e-18
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 94 1e-18
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 94 1e-18
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 94 1e-18
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 94 1e-18
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 94 1e-18
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 94 1e-18
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 94 1e-18
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 94 1e-18
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 94 1e-18
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 94 1e-18
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 94 1e-18
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 94 1e-18
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 93 1e-18
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 93 1e-18
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 93 1e-18
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 93 1e-18
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 93 1e-18
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 93 1e-18
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 93 1e-18
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 93 1e-18
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 93 1e-18
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 93 2e-18
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 93 2e-18
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 93 2e-18
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 93 2e-18
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 93 2e-18
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 93 2e-18
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 93 2e-18
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 93 2e-18
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 93 2e-18
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 93 2e-18
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 92 3e-18
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 92 3e-18
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 92 3e-18
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 92 3e-18
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 92 3e-18
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 92 3e-18
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 92 4e-18
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 92 4e-18
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 91 5e-18
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 91 7e-18
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 90 1e-17
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 90 1e-17
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 90 1e-17
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 90 1e-17
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 90 1e-17
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 90 2e-17
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 89 2e-17
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 89 2e-17
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 89 2e-17
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 89 2e-17
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 89 2e-17
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 89 3e-17
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 89 3e-17
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 89 4e-17
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 89 4e-17
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 88 5e-17
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 87 1e-16
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 87 1e-16
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 87 1e-16
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 87 1e-16
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 87 1e-16
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 87 1e-16
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 87 1e-16
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 87 1e-16
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 87 1e-16
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 87 1e-16
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 87 1e-16
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 87 1e-16
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 87 1e-16
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 87 1e-16
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 87 1e-16
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 87 1e-16
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 87 1e-16
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 87 1e-16
AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family... 87 1e-16
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 86 2e-16
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 86 2e-16
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 86 2e-16
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 86 2e-16
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 86 3e-16
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 85 3e-16
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 85 4e-16
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 85 4e-16
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 85 4e-16
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 85 4e-16
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 85 4e-16
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 85 4e-16
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 85 4e-16
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 85 4e-16
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 85 4e-16
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 85 6e-16
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 85 6e-16
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 84 8e-16
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 84 1e-15
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 83 2e-15
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 83 2e-15
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 82 3e-15
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 82 3e-15
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 82 3e-15
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 82 3e-15
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 82 3e-15
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 82 4e-15
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 81 5e-15
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 81 5e-15
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 81 5e-15
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 81 5e-15
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 81 7e-15
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 81 1e-14
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 81 1e-14
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 81 1e-14
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 81 1e-14
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 80 2e-14
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 80 2e-14
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 80 2e-14
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 80 2e-14
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 80 2e-14
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 80 2e-14
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 79 2e-14
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 79 2e-14
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 79 2e-14
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 79 2e-14
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 79 2e-14
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 79 2e-14
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 79 2e-14
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 79 4e-14
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 78 7e-14
BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein. 78 7e-14
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 78 7e-14
AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 78 7e-14
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 78 7e-14
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 78 7e-14
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 77 1e-13
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 77 1e-13
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 77 2e-13
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 76 3e-13
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 76 3e-13
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 76 3e-13
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 76 3e-13
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 76 3e-13
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 76 3e-13
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 76 3e-13
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 76 3e-13
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 76 3e-13
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 76 3e-13
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 76 3e-13
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 76 3e-13
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 76 3e-13
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 76 3e-13
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 76 3e-13
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 75 5e-13
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 75 5e-13
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 75 5e-13
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 75 6e-13
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 75 6e-13
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 75 6e-13
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 75 6e-13
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 75 6e-13
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 75 6e-13
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 75 6e-13
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 75 6e-13
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 75 6e-13
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 75 6e-13
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 75 6e-13
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 74 8e-13
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 74 8e-13
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 74 8e-13
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 74 1e-12
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 74 1e-12
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 74 1e-12
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 74 1e-12
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 74 1e-12
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 74 1e-12
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 74 1e-12
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 74 1e-12
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 74 1e-12
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 74 1e-12
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 74 1e-12
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 74 1e-12
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 74 1e-12
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 74 1e-12
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 74 1e-12
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 74 1e-12
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 73 1e-12
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 73 1e-12
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 73 1e-12
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 73 2e-12
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 73 2e-12
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 73 2e-12
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 71 6e-12
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 71 6e-12
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 71 6e-12
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 71 6e-12
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 71 8e-12
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 71 8e-12
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 71 1e-11
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 71 1e-11
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 70 1e-11
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 70 1e-11
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 70 2e-11
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 70 2e-11
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 70 2e-11
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 70 2e-11
BX679671-8|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 70 2e-11
BX679671-7|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 70 2e-11
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 70 2e-11
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 70 2e-11
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 70 2e-11
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 70 2e-11
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 70 2e-11
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 70 2e-11
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 70 2e-11
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 70 2e-11
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 70 2e-11
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 70 2e-11
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 70 2e-11
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 70 2e-11
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 70 2e-11
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 70 2e-11
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 70 2e-11
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 70 2e-11
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 70 2e-11
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 69 3e-11
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 69 4e-11
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 68 5e-11
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 68 7e-11
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 68 7e-11
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 68 7e-11
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 68 7e-11
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 68 7e-11
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 68 7e-11
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 68 7e-11
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 68 7e-11
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 68 7e-11
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 68 7e-11
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 68 7e-11
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 68 7e-11
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 68 7e-11
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 68 7e-11
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 68 7e-11
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 68 7e-11
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 68 7e-11
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 67 9e-11
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 67 1e-10
AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 67 1e-10
BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 66 2e-10
BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 66 2e-10
BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 66 2e-10
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 66 2e-10
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 66 2e-10
AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 65 5e-10
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 64 7e-10
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 64 7e-10
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 64 7e-10
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 64 7e-10
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 64 7e-10
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 64 9e-10
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 64 9e-10
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 64 9e-10
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 64 1e-09
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 64 1e-09
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 62 3e-09
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 62 4e-09
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 62 4e-09
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 59 3e-08
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 59 3e-08
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 59 3e-08
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 59 3e-08
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 59 3e-08
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 59 3e-08
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 59 3e-08
AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1 pro... 58 4e-08
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 57 1e-07
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 57 1e-07
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 54 7e-07
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 54 7e-07
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 54 7e-07
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 54 9e-07
AC011737-1|AAX88915.1| 382|Homo sapiens unknown protein. 54 9e-07
AM233518-1|CAJ80721.1| 157|Homo sapiens cytochrome P450 1A1 pro... 53 2e-06
AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 48 6e-05
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 48 8e-05
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 48 8e-05
AL138805-2|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 48 8e-05
AF297052-1|AAG31785.1| 500|Homo sapiens prostacyclin synthase p... 46 3e-04
D84124-1|BAA28219.1| 509|Homo sapiens prostacyclin synthase pro... 45 6e-04
D83402-1|BAA11910.1| 500|Homo sapiens prostacyclin synthase pro... 45 6e-04
D38145-1|BAA07343.1| 500|Homo sapiens prostacyclin synthase pro... 45 6e-04
BC101811-1|AAI01812.1| 500|Homo sapiens prostaglandin I2 (prost... 45 6e-04
BC101809-1|AAI01810.1| 500|Homo sapiens prostaglandin I2 (prost... 45 6e-04
AL118525-1|CAC14162.1| 500|Homo sapiens prostaglandin I2 (prost... 45 6e-04
AF297051-1|AAG31784.1| 500|Homo sapiens prostacyclin synthase p... 45 6e-04
AF297050-1|AAG31783.1| 500|Homo sapiens prostacyclin synthase p... 45 6e-04
AF297049-1|AAG31782.1| 500|Homo sapiens prostacyclin synthase p... 45 6e-04
AF297048-1|AAG31781.1| 500|Homo sapiens prostacyclin synthase p... 45 6e-04
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 44 8e-04
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 44 8e-04
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 43 0.002
BC128535-1|AAI28536.1| 143|Homo sapiens LOC283480 protein protein. 42 0.003
BC067444-1|AAH67444.1| 501|Homo sapiens cytochrome P450, family... 42 0.003
BC067442-1|AAH67442.1| 501|Homo sapiens cytochrome P450, family... 42 0.003
BC067441-1|AAH67441.1| 501|Homo sapiens cytochrome P450, family... 42 0.003
BC067434-1|AAH67434.1| 501|Homo sapiens cytochrome P450, family... 42 0.003
AF090320-1|AAD19877.1| 501|Homo sapiens sterol 12-alpha-hydroxy... 42 0.003
AF090318-1|AAC63037.1| 462|Homo sapiens sterol 12-alpha hydroxy... 42 0.003
X56088-1|CAA39568.1| 504|Homo sapiens cholesterol 7-alpha-hydr... 42 0.005
M93133-1|AAA58435.1| 504|Homo sapiens cholesterol 7-alpha hydro... 41 0.009
BC112184-1|AAI12185.1| 504|Homo sapiens cytochrome P450, family... 41 0.009
BC101777-1|AAI01778.1| 504|Homo sapiens cytochrome P450, family... 41 0.009
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 40 0.012
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 40 0.012
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 40 0.012
X58899-1|CAA41703.1| 368|Homo sapiens steroid 21-monooxygenase ... 40 0.012
X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase ... 40 0.012
BC019254-1|AAH19254.2| 455|Homo sapiens ENOX2 protein protein. 40 0.016
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 40 0.016
AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 40 0.016
BC139781-1|AAI39782.2| 638|Homo sapiens ENOX2 protein protein. 39 0.038
BC108713-1|AAI08714.1| 468|Homo sapiens Unknown (protein for IM... 39 0.038
AL591908-2|CAH71676.1| 610|Homo sapiens cytosolic ovarian carci... 39 0.038
AL591908-1|CAH71675.1| 581|Homo sapiens cytosolic ovarian carci... 39 0.038
AL049733-4|CAI43114.1| 610|Homo sapiens cytosolic ovarian carci... 39 0.038
AL049733-3|CAI43113.1| 581|Homo sapiens cytosolic ovarian carci... 39 0.038
AF207881-1|AAF20934.2| 610|Homo sapiens tumor-associated hydroq... 39 0.038
AC005336-2|AAC27731.1| 93|Homo sapiens F20191_1, partial CDS p... 38 0.066
BC029155-1|AAH29155.1| 489|Homo sapiens Unknown (protein for IM... 37 0.12
AF176805-1|AAK11850.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 37 0.12
AF127090-1|AAD20021.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 37 0.12
AF029403-1|AAC95426.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 37 0.12
AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 36 0.27
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 36 0.35
BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 35 0.62
S72904-1|AAB30428.1| 263|Homo sapiens APK1 antigen protein. 34 1.1
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 34 1.1
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 34 1.1
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 34 1.1
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 34 1.1
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 34 1.1
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 34 1.1
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 34 1.1
AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 33 1.4
D38498-1|BAA07510.1| 186|Homo sapiens PMS5 protein. 32 4.4
D38437-1|BAA07472.1| 186|Homo sapiens hPMS5 protein. 32 4.4
U90028-1|AAB94805.1| 975|Homo sapiens bicaudal-D protein. 31 7.6
D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein. 31 7.6
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 31 7.6
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 31 7.6
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 31 7.6
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 31 7.6
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 31 7.6
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 210 bits (512), Expect = 9e-54
Identities = 101/231 (43%), Positives = 146/231 (63%), Gaps = 2/231 (0%)
Query: 183 EKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQ 242
+ KR AFLDL++ + +S +I+EEVDT MFEGHDTTAA ++ L LLG + E+Q
Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352
Query: 243 SKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNN 302
KV EL ++FG SDR T D +++YLE VI E+LRL+P VP AR ++ D ++
Sbjct: 353 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 410
Query: 303 YIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 362
Y + G+ VI + +HRDP+Y NP F P+ F PEN Q RH Y+Y+PFSAGPR+C+G+
Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 470
Query: 363 KYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEPRN 413
K+A S ILR++ S ++ L+ +IL+ +G I+++ RN
Sbjct: 471 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRN 521
Score = 76.6 bits (180), Expect = 2e-13
Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 1/124 (0%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGK-TFDVHDYMSCVTVDILLETAMGIT 59
M+ PTFH IL+ F+ + NE + +VKKL + + F+ Y++ +DI+ ETAMG
Sbjct: 149 MLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKN 208
Query: 60 KTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNKV 119
Q +Y AV +M +I +R WL D + + + ++ LK +H TN V
Sbjct: 209 IGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKILHTFTNSV 268
Query: 120 IKKK 123
I ++
Sbjct: 269 IAER 272
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 210 bits (512), Expect = 9e-54
Identities = 101/231 (43%), Positives = 146/231 (63%), Gaps = 2/231 (0%)
Query: 183 EKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQ 242
+ KR AFLDL++ + +S +I+EEVDT MFEGHDTTAA ++ L LLG + E+Q
Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352
Query: 243 SKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNN 302
KV EL ++FG SDR T D +++YLE VI E+LRL+P VP AR ++ D ++
Sbjct: 353 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 410
Query: 303 YIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 362
Y + G+ VI + +HRDP+Y NP F P+ F PEN Q RH Y+Y+PFSAGPR+C+G+
Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 470
Query: 363 KYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEPRN 413
K+A S ILR++ S ++ L+ +IL+ +G I+++ RN
Sbjct: 471 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRN 521
Score = 76.6 bits (180), Expect = 2e-13
Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 1/124 (0%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGK-TFDVHDYMSCVTVDILLETAMGIT 59
M+ PTFH IL+ F+ + NE + +VKKL + + F+ Y++ +DI+ ETAMG
Sbjct: 149 MLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKN 208
Query: 60 KTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNKV 119
Q +Y AV +M +I +R WL D + + + ++ LK +H TN V
Sbjct: 209 IGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKILHTFTNSV 268
Query: 120 IKKK 123
I ++
Sbjct: 269 IAER 272
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 210 bits (512), Expect = 9e-54
Identities = 101/231 (43%), Positives = 146/231 (63%), Gaps = 2/231 (0%)
Query: 183 EKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQ 242
+ KR AFLDL++ + +S +I+EEVDT MFEGHDTTAA ++ L LLG + E+Q
Sbjct: 271 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 330
Query: 243 SKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNN 302
KV EL ++FG SDR T D +++YLE VI E+LRL+P VP AR ++ D ++
Sbjct: 331 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 388
Query: 303 YIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 362
Y + G+ VI + +HRDP+Y NP F P+ F PEN Q RH Y+Y+PFSAGPR+C+G+
Sbjct: 389 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 448
Query: 363 KYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEPRN 413
K+A S ILR++ S ++ L+ +IL+ +G I+++ RN
Sbjct: 449 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRN 499
Score = 76.6 bits (180), Expect = 2e-13
Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 1/124 (0%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGK-TFDVHDYMSCVTVDILLETAMGIT 59
M+ PTFH IL+ F+ + NE + +VKKL + + F+ Y++ +DI+ ETAMG
Sbjct: 127 MLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKN 186
Query: 60 KTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNKV 119
Q +Y AV +M +I +R WL D + + + ++ LK +H TN V
Sbjct: 187 IGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKILHTFTNSV 246
Query: 120 IKKK 123
I ++
Sbjct: 247 IAER 250
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 210 bits (512), Expect = 9e-54
Identities = 101/231 (43%), Positives = 146/231 (63%), Gaps = 2/231 (0%)
Query: 183 EKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQ 242
+ KR AFLDL++ + +S +I+EEVDT MFEGHDTTAA ++ L LLG + E+Q
Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352
Query: 243 SKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNN 302
KV EL ++FG SDR T D +++YLE VI E+LRL+P VP AR ++ D ++
Sbjct: 353 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 410
Query: 303 YIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGR 362
Y + G+ VI + +HRDP+Y NP F P+ F PEN Q RH Y+Y+PFSAGPR+C+G+
Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 470
Query: 363 KYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEPRN 413
K+A S ILR++ S ++ L+ +IL+ +G I+++ RN
Sbjct: 471 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRN 521
Score = 76.6 bits (180), Expect = 2e-13
Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 1/124 (0%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGK-TFDVHDYMSCVTVDILLETAMGIT 59
M+ PTFH IL+ F+ + NE + +VKKL + + F+ Y++ +DI+ ETAMG
Sbjct: 149 MLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKN 208
Query: 60 KTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNKV 119
Q +Y AV +M +I +R WL D + + + ++ LK +H TN V
Sbjct: 209 IGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKILHTFTNSV 268
Query: 120 IKKK 123
I ++
Sbjct: 269 IAER 272
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 167 bits (407), Expect = 5e-41
Identities = 92/267 (34%), Positives = 151/267 (56%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL+ +G D L Q + K L F+D+++ S + +S
Sbjct: 263 VHDFTDAVIQERRRTLTS---QGVDDFL-----QAKAKSKTLDFIDVLLLSEDKNGKELS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MF GHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
Q+ +L + ESLRL+PP+P AR T+DV ++ ++ +IP G+ I F IH +P
Sbjct: 375 LAQLPFLTMCLKESLRLHPPIPTFARGCTQDV-VLPDSRVIPKGNVCNINIFAIHHNPSV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F PEN Q R ++IPFSAGPR+C+G+K+A + L ++
Sbjct: 434 WPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ E + +I+L+ DG +R+EP
Sbjct: 494 DHREPR--RTPEIVLRAEDGLWLRVEP 518
Score = 58.8 bits (136), Expect = 3e-08
Identities = 42/183 (22%), Positives = 89/183 (48%), Gaps = 13/183 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH NILK ++ +F++++ + K L E DV +++S +T+D L +
Sbjct: 150 LLTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHISLMTLDSLQKCIFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A+M++ ++ +R+ + + + D ++ LT ++ + +H T+
Sbjct: 210 FDSNCQEKPS-EYITAIMELSALVVKRNNQFFRYKDFLYFLTPCGRRFHRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDTVFKG 168
VI++++ +LQ K K I+ L +D N + ++ + +DT G
Sbjct: 269 AVIQERRRTLTSQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFG 328
Query: 169 YRD 171
D
Sbjct: 329 GHD 331
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 160 bits (388), Expect = 1e-38
Identities = 88/267 (32%), Positives = 149/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
Q+ +L I ESLRL+PPVPA++R T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAQLPFLTMCIKESLRLHPPVPAVSRCCTQDI-VLPDGRVIPKGIICLISVFGTHHNPAV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F P+N + R ++IPFSAGPR+C+G+ +A L ++
Sbjct: 434 WPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 71.3 bits (167), Expect = 6e-12
Identities = 48/182 (26%), Positives = 94/182 (51%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH ++ L+ D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 160 bits (388), Expect = 1e-38
Identities = 88/267 (32%), Positives = 149/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
Q+ +L I ESLRL+PPVPA++R T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAQLPFLTMCIKESLRLHPPVPAVSRCCTQDI-VLPDGRVIPKGIICLISVFGTHHNPAV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F P+N + R ++IPFSAGPR+C+G+ +A L ++
Sbjct: 434 WPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGIWLRVEP 518
Score = 68.5 bits (160), Expect = 4e-11
Identities = 47/182 (25%), Positives = 94/182 (51%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L S+ D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASKGYARLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH ++ L+ D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 159 bits (386), Expect = 2e-38
Identities = 87/267 (32%), Positives = 149/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
+ +L + ESLRL+PPVP I+R +T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAHLPFLTMCMKESLRLHPPVPVISRHVTQDI-VLPDGRVIPKGIICLISVFGTHHNPAV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F PEN + R ++IPFSAGPR+C+G+ +A + L ++
Sbjct: 434 WPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 75.4 bits (177), Expect = 4e-13
Identities = 49/182 (26%), Positives = 95/182 (52%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 159 bits (386), Expect = 2e-38
Identities = 87/267 (32%), Positives = 149/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
+ +L + ESLRL+PPVP I+R +T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAHLPFLTMCMKESLRLHPPVPVISRHVTQDI-VLPDGRVIPKGIICLISVFGTHHNPAM 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F PEN + R ++IPFSAGPR+C+G+ +A + L ++
Sbjct: 434 WPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 74.1 bits (174), Expect = 8e-13
Identities = 48/182 (26%), Positives = 95/182 (52%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FN++ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNDSVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 159 bits (386), Expect = 2e-38
Identities = 87/267 (32%), Positives = 149/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
+ +L + ESLRL+PPVP I+R +T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAHLPFLTMCMKESLRLHPPVPVISRHVTQDI-VLPDGRVIPKGIICLISVFGTHHNPAV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F PEN + R ++IPFSAGPR+C+G+ +A + L ++
Sbjct: 434 WPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 75.4 bits (177), Expect = 4e-13
Identities = 49/182 (26%), Positives = 95/182 (52%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 159 bits (386), Expect = 2e-38
Identities = 87/267 (32%), Positives = 149/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
+ +L + ESLRL+PPVP I+R +T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAHLPFLTMCMKESLRLHPPVPVISRHVTQDI-VLPDGRVIPKGIICLISVFGTHHNPAV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F PEN + R ++IPFSAGPR+C+G+ +A + L ++
Sbjct: 434 WPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 75.4 bits (177), Expect = 4e-13
Identities = 49/182 (26%), Positives = 95/182 (52%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 159 bits (386), Expect = 2e-38
Identities = 87/267 (32%), Positives = 149/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
+ +L + ESLRL+PPVP I+R +T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAHLPFLTMCMKESLRLHPPVPVISRHVTQDI-VLPDGRVIPKGIICLISVFGTHHNPAV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F PEN + R ++IPFSAGPR+C+G+ +A + L ++
Sbjct: 434 WPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 75.4 bits (177), Expect = 4e-13
Identities = 49/182 (26%), Positives = 95/182 (52%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 159 bits (386), Expect = 2e-38
Identities = 87/267 (32%), Positives = 149/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
+ +L + ESLRL+PPVP I+R +T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAHLPFLTMCMKESLRLHPPVPVISRHVTQDI-VLPDGRVIPKGIICLISVFGTHHNPAV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F PEN + R ++IPFSAGPR+C+G+ +A + L ++
Sbjct: 434 WPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 75.4 bits (177), Expect = 4e-13
Identities = 49/182 (26%), Positives = 95/182 (52%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 159 bits (386), Expect = 2e-38
Identities = 87/267 (32%), Positives = 149/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
+ +L + ESLRL+PPVP I+R +T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAHLPFLTMCMKESLRLHPPVPVISRHVTQDI-VLPDGRVIPKGIICLISVFGTHHNPAM 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F PEN + R ++IPFSAGPR+C+G+ +A + L ++
Sbjct: 434 WPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 75.4 bits (177), Expect = 4e-13
Identities = 49/182 (26%), Positives = 95/182 (52%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 159 bits (385), Expect = 2e-38
Identities = 88/267 (32%), Positives = 148/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D ++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDDVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
Q+ +L I ESLRL+PPVPA++R T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAQLPFLTMCIKESLRLHPPVPAVSRCCTQDI-VLPDGRVIPKGIICLISVFGTHHNPAV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F P+N + R ++IPFSAGPR+C+G+ +A L ++
Sbjct: 434 WPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 71.3 bits (167), Expect = 6e-12
Identities = 48/182 (26%), Positives = 94/182 (51%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH ++ L+ D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 DVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 159 bits (385), Expect = 2e-38
Identities = 82/236 (34%), Positives = 138/236 (58%), Gaps = 4/236 (1%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+D + K L F+D+++ S +SD +I+ E DT MF GHDTTA+G S+VL L H
Sbjct: 288 KDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARH 347
Query: 239 QEIQSKVYDELFEIFGDSD-RLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQ 297
E Q + E+ E+ D D + + + D Q+ +L + ESLRL+PP P I+R T+D+
Sbjct: 348 PEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDI- 406
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPR 357
++ + +IP G T +I +H +P +P V++P F PEN++ R ++IPFSAGPR
Sbjct: 407 VLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPR 466
Query: 358 SCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEPRN 413
+C+G+ +A + +L +++ + +E + L ++I++ G +R+EP N
Sbjct: 467 NCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKL--ELIMRAEGGLWLRVEPLN 520
Score = 64.1 bits (149), Expect = 9e-10
Identities = 31/127 (24%), Positives = 69/127 (54%), Gaps = 4/127 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILKS++ +FN+++ ++ K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLDSLQKCIFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y ++++ ++ +R + H D ++ L+ ++ + +H T+
Sbjct: 210 FDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTD 268
Query: 118 KVIKKKK 124
VI++++
Sbjct: 269 AVIRERR 275
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 159 bits (385), Expect = 2e-38
Identities = 82/236 (34%), Positives = 138/236 (58%), Gaps = 4/236 (1%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+D + K L F+D+++ S +SD +I+ E DT MF GHDTTA+G S+VL L H
Sbjct: 288 KDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARH 347
Query: 239 QEIQSKVYDELFEIFGDSD-RLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQ 297
E Q + E+ E+ D D + + + D Q+ +L + ESLRL+PP P I+R T+D+
Sbjct: 348 PEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDI- 406
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPR 357
++ + +IP G T +I +H +P +P V++P F PEN++ R ++IPFSAGPR
Sbjct: 407 VLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPR 466
Query: 358 SCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEPRN 413
+C+G+ +A + +L +++ + +E + L ++I++ G +R+EP N
Sbjct: 467 NCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKL--ELIMRAEGGLWLRVEPLN 520
Score = 64.1 bits (149), Expect = 9e-10
Identities = 31/127 (24%), Positives = 69/127 (54%), Gaps = 4/127 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILKS++ +FN+++ ++ K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y ++++ ++ +R + H D ++ L+ ++ + +H T+
Sbjct: 210 FDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTD 268
Query: 118 KVIKKKK 124
VI++++
Sbjct: 269 AVIRERR 275
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 159 bits (385), Expect = 2e-38
Identities = 82/236 (34%), Positives = 138/236 (58%), Gaps = 4/236 (1%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+D + K L F+D+++ S +SD +I+ E DT MF GHDTTA+G S+VL L H
Sbjct: 288 KDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARH 347
Query: 239 QEIQSKVYDELFEIFGDSD-RLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQ 297
E Q + E+ E+ D D + + + D Q+ +L + ESLRL+PP P I+R T+D+
Sbjct: 348 PEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDI- 406
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPR 357
++ + +IP G T +I +H +P +P V++P F PEN++ R ++IPFSAGPR
Sbjct: 407 VLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPR 466
Query: 358 SCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEPRN 413
+C+G+ +A + +L +++ + +E + L ++I++ G +R+EP N
Sbjct: 467 NCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKL--ELIMRAEGGLWLRVEPLN 520
Score = 64.1 bits (149), Expect = 9e-10
Identities = 31/127 (24%), Positives = 69/127 (54%), Gaps = 4/127 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILKS++ +FN+++ ++ K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y ++++ ++ +R + H D ++ L+ ++ + +H T+
Sbjct: 210 FDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTD 268
Query: 118 KVIKKKK 124
VI++++
Sbjct: 269 AVIRERR 275
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 159 bits (385), Expect = 2e-38
Identities = 82/236 (34%), Positives = 138/236 (58%), Gaps = 4/236 (1%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+D + K L F+D+++ S +SD +I+ E DT MF GHDTTA+G S+VL L H
Sbjct: 222 KDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARH 281
Query: 239 QEIQSKVYDELFEIFGDSD-RLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQ 297
E Q + E+ E+ D D + + + D Q+ +L + ESLRL+PP P I+R T+D+
Sbjct: 282 PEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDI- 340
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPR 357
++ + +IP G T +I +H +P +P V++P F PEN++ R ++IPFSAGPR
Sbjct: 341 VLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPR 400
Query: 358 SCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEPRN 413
+C+G+ +A + +L +++ + +E + L ++I++ G +R+EP N
Sbjct: 401 NCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKL--ELIMRAEGGLWLRVEPLN 454
Score = 64.1 bits (149), Expect = 9e-10
Identities = 31/127 (24%), Positives = 69/127 (54%), Gaps = 4/127 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILKS++ +FN+++ ++ K L SE D+ +++S +T+D L +
Sbjct: 84 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLDSLQKCIFS 143
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y ++++ ++ +R + H D ++ L+ ++ + +H T+
Sbjct: 144 FDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTD 202
Query: 118 KVIKKKK 124
VI++++
Sbjct: 203 AVIRERR 209
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 159 bits (385), Expect = 2e-38
Identities = 82/236 (34%), Positives = 138/236 (58%), Gaps = 4/236 (1%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+D + K L F+D+++ S +SD +I+ E DT MF GHDTTA+G S+VL L H
Sbjct: 288 KDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARH 347
Query: 239 QEIQSKVYDELFEIFGDSD-RLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQ 297
E Q + E+ E+ D D + + + D Q+ +L + ESLRL+PP P I+R T+D+
Sbjct: 348 PEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDI- 406
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPR 357
++ + +IP G T +I +H +P +P V++P F PEN++ R ++IPFSAGPR
Sbjct: 407 VLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPR 466
Query: 358 SCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEPRN 413
+C+G+ +A + +L +++ + +E + L ++I++ G +R+EP N
Sbjct: 467 NCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKL--ELIMRAEGGLWLRVEPLN 520
Score = 64.1 bits (149), Expect = 9e-10
Identities = 31/127 (24%), Positives = 69/127 (54%), Gaps = 4/127 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILKS++ +FN+++ ++ K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y ++++ ++ +R + H D ++ L+ ++ + +H T+
Sbjct: 210 FDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTD 268
Query: 118 KVIKKKK 124
VI++++
Sbjct: 269 AVIRERR 275
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 159 bits (385), Expect = 2e-38
Identities = 82/236 (34%), Positives = 138/236 (58%), Gaps = 4/236 (1%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+D + K L F+D+++ S +SD +I+ E DT MF GHDTTA+G S+VL L H
Sbjct: 288 KDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARH 347
Query: 239 QEIQSKVYDELFEIFGDSD-RLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQ 297
E Q + E+ E+ D D + + + D Q+ +L + ESLRL+PP P I+R T+D+
Sbjct: 348 PEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDI- 406
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPR 357
++ + +IP G T +I +H +P +P V++P F PEN++ R ++IPFSAGPR
Sbjct: 407 VLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPR 466
Query: 358 SCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEPRN 413
+C+G+ +A + +L +++ + +E + L ++I++ G +R+EP N
Sbjct: 467 NCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKL--ELIMRAEGGLWLRVEPLN 520
Score = 64.1 bits (149), Expect = 9e-10
Identities = 31/127 (24%), Positives = 69/127 (54%), Gaps = 4/127 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILKS++ +FN+++ ++ K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y ++++ ++ +R + H D ++ L+ ++ + +H T+
Sbjct: 210 FDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTD 268
Query: 118 KVIKKKK 124
VI++++
Sbjct: 269 AVIRERR 275
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 159 bits (385), Expect = 2e-38
Identities = 88/267 (32%), Positives = 148/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D ++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDDVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
Q+ +L I ESLRL+PPVPA++R T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAQLPFLTMCIKESLRLHPPVPAVSRCCTQDI-VLPDGRVIPKGIICLISVFGTHHNPAV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F P+N + R ++IPFSAGPR+C+G+ +A L ++
Sbjct: 434 WPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 71.3 bits (167), Expect = 6e-12
Identities = 48/182 (26%), Positives = 94/182 (51%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH ++ L+ D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 DVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 159 bits (385), Expect = 2e-38
Identities = 88/267 (32%), Positives = 148/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D ++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDDVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
Q+ +L I ESLRL+PPVPA++R T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAQLPFLTMCIKESLRLHPPVPAVSRCCTQDI-VLPDGRVIPKGIICLISVFGTHHNPAV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F P+N + R ++IPFSAGPR+C+G+ +A L ++
Sbjct: 434 WPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 71.3 bits (167), Expect = 6e-12
Identities = 48/182 (26%), Positives = 94/182 (51%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH ++ L+ D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 DVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 337 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 504
Score = 54.4 bits (125), Expect = 7e-07
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K + GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNK 118
T Y +AV + ++ QR H D I+ LT ++ + H T++
Sbjct: 200 GDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQ 259
Query: 119 VIKKKK 124
VI+++K
Sbjct: 260 VIRERK 265
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 337 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 504
Score = 54.4 bits (125), Expect = 7e-07
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K + GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNK 118
T Y +AV + ++ QR H D I+ LT ++ + H T++
Sbjct: 200 GDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQ 259
Query: 119 VIKKKK 124
VI+++K
Sbjct: 260 VIRERK 265
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 337 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 504
Score = 54.4 bits (125), Expect = 7e-07
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K + GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNK 118
T Y +AV + ++ QR H D I+ LT ++ + H T++
Sbjct: 200 GDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQ 259
Query: 119 VIKKKK 124
VI+++K
Sbjct: 260 VIRERK 265
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 278 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 337
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 338 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 395
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 396 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 456 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 505
Score = 51.6 bits (118), Expect = 5e-06
Identities = 31/127 (24%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
T + Y +AV + ++ QR H D I+ LT ++ + H T+
Sbjct: 200 GDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTD 259
Query: 118 KVIKKKK 124
+VI+++K
Sbjct: 260 QVIRERK 266
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 155 bits (375), Expect = 4e-37
Identities = 89/271 (32%), Positives = 149/271 (54%), Gaps = 12/271 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L ++ + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPT---QGIDDFL-----KNKAKSKTLDFIDVLLLSKDEDGKELS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRL-VTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
Q+ +L I ESLRL+PPVP I+R T+D ++ + +IP G +I IH +P
Sbjct: 375 LAQLPFLTMCIKESLRLHPPVPVISRCCTQDF-VLPDGRVIPKGIVCLINIIGIHYNPTV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F EN + R ++IPFSAGPR+C+G+ +A + L +++
Sbjct: 434 WPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEPRNKN 415
+E + + ++IL+ G +R+EP N
Sbjct: 494 THTEPR--RKPELILRAEGGLWLRVEPLGAN 522
Score = 69.7 bits (163), Expect = 2e-11
Identities = 47/182 (25%), Positives = 93/182 (51%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FN++ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ + +R+ ++ LH D ++ LT ++ R +H T+
Sbjct: 210 FESNCQEKPS-EYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +L+NK K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 263 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 322
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 323 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 380
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 381 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 440
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 441 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 490
Score = 51.6 bits (118), Expect = 5e-06
Identities = 31/127 (24%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++ G
Sbjct: 125 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 184
Query: 59 TKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
T + Y +AV + ++ QR H D I+ LT ++ + H T+
Sbjct: 185 GDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTD 244
Query: 118 KVIKKKK 124
+VI+++K
Sbjct: 245 QVIRERK 251
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 278 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 337
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 338 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 395
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 396 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 456 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 505
Score = 51.6 bits (118), Expect = 5e-06
Identities = 31/127 (24%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
T + Y +AV + ++ QR H D I+ LT ++ + H T+
Sbjct: 200 GDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTD 259
Query: 118 KVIKKKK 124
+VI+++K
Sbjct: 260 QVIRERK 266
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 337 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 504
Score = 54.4 bits (125), Expect = 7e-07
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K + GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAWEGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNK 118
T Y +AV + ++ QR H D I+ LT ++ + H T++
Sbjct: 200 GDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQ 259
Query: 119 VIKKKK 124
VI+++K
Sbjct: 260 VIRERK 265
>AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 263 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 322
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 323 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 380
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 381 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 440
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 441 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 490
Score = 51.6 bits (118), Expect = 5e-06
Identities = 31/127 (24%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++ G
Sbjct: 125 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 184
Query: 59 TKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
T + Y +AV + ++ QR H D I+ LT ++ + H T+
Sbjct: 185 GDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTD 244
Query: 118 KVIKKKK 124
+VI+++K
Sbjct: 245 QVIRERK 251
>AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 278 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 337
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 338 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 395
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 396 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 456 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 505
Score = 51.6 bits (118), Expect = 5e-06
Identities = 31/127 (24%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
T + Y +AV + ++ QR H D I+ LT ++ + H T+
Sbjct: 200 GDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTD 259
Query: 118 KVIKKKK 124
+VI+++K
Sbjct: 260 QVIRERK 266
>AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 337 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 504
Score = 54.4 bits (125), Expect = 7e-07
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K + GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNK 118
T Y +AV + ++ QR H D I+ LT ++ + H T++
Sbjct: 200 GDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQ 259
Query: 119 VIKKKK 124
VI+++K
Sbjct: 260 VIRERK 265
>AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 337 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 504
Score = 54.4 bits (125), Expect = 7e-07
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K + GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNK 118
T Y +AV + ++ QR H D I+ LT ++ + H T++
Sbjct: 200 GDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQ 259
Query: 119 VIKKKK 124
VI+++K
Sbjct: 260 VIRERK 265
>AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 278 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 337
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 338 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 395
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 396 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 456 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 505
Score = 51.6 bits (118), Expect = 5e-06
Identities = 31/127 (24%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
T + Y +AV + ++ QR H D I+ LT ++ + H T+
Sbjct: 200 GDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTD 259
Query: 118 KVIKKKK 124
+VI+++K
Sbjct: 260 QVIRERK 266
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 263 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 322
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 323 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 380
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 381 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 440
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 441 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 490
Score = 51.6 bits (118), Expect = 5e-06
Identities = 31/127 (24%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++ G
Sbjct: 125 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 184
Query: 59 TKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
T + Y +AV + ++ QR H D I+ LT ++ + H T+
Sbjct: 185 GDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTD 244
Query: 118 KVIKKKK 124
+VI+++K
Sbjct: 245 QVIRERK 251
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 155 bits (375), Expect = 4e-37
Identities = 77/231 (33%), Positives = 133/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT +G S+ L + ++ E
Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCIALYPE 336
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 337 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 504
Score = 54.4 bits (125), Expect = 7e-07
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K + GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNK 118
T Y +AV + ++ QR H D I+ LT ++ + H T++
Sbjct: 200 GDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQ 259
Query: 119 VIKKKK 124
VI+++K
Sbjct: 260 VIRERK 265
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 154 bits (374), Expect = 5e-37
Identities = 85/267 (31%), Positives = 148/267 (55%), Gaps = 12/267 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L Q + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPS---QGVDDFL-----QAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSD-RLVTFAD 264
D +I+ E DT MFEGHDTTA+ S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASVLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
+ +L + ESLR++PPVP I+R +T+D+ ++ + +IP G +I F H +P
Sbjct: 375 LAHLPFLTMCMKESLRVHPPVPVISRHVTQDI-VLPDGRVIPKGIICLISVFGTHHNPAV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F PEN + R ++IPFSAGPR+C+G+ +A + L ++
Sbjct: 434 WPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEP 411
+ +E + + +++L+ G +R+EP
Sbjct: 494 DHTEPR--RKPELVLRAEGGLWLRVEP 518
Score = 75.4 bits (177), Expect = 4e-13
Identities = 49/182 (26%), Positives = 95/182 (52%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT ++ R + +H T+
Sbjct: 210 FDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +LQ K K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 154 bits (374), Expect = 5e-37
Identities = 77/231 (33%), Positives = 132/231 (57%), Gaps = 3/231 (1%)
Query: 181 VGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQE 240
+ ++ L FLD+++ + +SD +++ EVDT MFEGHDTT G S+ L + ++ E
Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTGGISWFLYCMALYPE 336
Query: 241 IQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVT 300
Q + +E+ EI GD D + D +M YL I ES RLYPPVP + R+L++ V V
Sbjct: 337 HQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394
Query: 301 NNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCV 360
+ +PAGS + + + +HR+ +P VF+ F EN RH ++++PFSAGPR+C+
Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
Query: 361 GRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
G+++A + L ++ + + S + ++L+ +GF + ++P
Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLP-IKMPQLVLRSKNGFHLHLKP 504
Score = 54.4 bits (125), Expect = 7e-07
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 2/126 (1%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLETAMGI 58
++ P FH ++LK ++ VF E+++ ++ K + GK+FD+ + + ++ L++ G
Sbjct: 140 LLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGR 199
Query: 59 TKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTNK 118
T Y +AV + ++ QR H D I+ LT ++ + H T++
Sbjct: 200 GDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQ 259
Query: 119 VIKKKK 124
VI+++K
Sbjct: 260 VIRERK 265
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 153 bits (372), Expect = 8e-37
Identities = 89/271 (32%), Positives = 148/271 (54%), Gaps = 12/271 (4%)
Query: 146 IKDTNDSIMEDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNIS 205
+ D D+++++ +TL +G D L ++ + K L F+D+++ S +S
Sbjct: 263 VHDFTDAVIQERRRTLPT---QGIDDFL-----KNKAKSKTLDFIDVLLLSKDEDGKELS 314
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRL-VTFAD 264
D +I+ E DT MFEGHDTTA+G S+VL L H E Q + E+ E+ D + + + + D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDD 374
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
Q+ +L I ESLRL+PPVP I+R T+D ++ + +IP G +I IH +P
Sbjct: 375 LAQLPFLTMCIKESLRLHPPVPVISRCCTQDF-VLPDGRVIPKGIVCLINIIGIHYNPTV 433
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P V++P F EN + R ++IPFSAGPR+C+G+ +A + L +++
Sbjct: 434 WPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILP 493
Query: 385 EISEDQFVLQADIILKRYDGFKIRIEPRNKN 415
E + + ++IL+ G +R+EP N
Sbjct: 494 THIEPR--RKPELILRAEGGLWLRVEPLGAN 522
Score = 69.7 bits (163), Expect = 2e-11
Identities = 47/182 (25%), Positives = 93/182 (51%), Gaps = 14/182 (7%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
M+ P FH NILK +M +FN++ + K L SE D+ +++S +T+D L +
Sbjct: 150 MLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFS 209
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S +Y A++++ + +R+ ++ LH D ++ LT ++ R +H T+
Sbjct: 210 FESNCQEKPS-EYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTD 268
Query: 118 KVIKKKKFM--------YLQNKEKGIIPPTIEELTKIKDTN-DSIMEDSAKTLSDT-VFK 167
VI++++ +L+NK K I+ L KD + + ++ + +DT +F+
Sbjct: 269 AVIQERRRTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFE 328
Query: 168 GY 169
G+
Sbjct: 329 GH 330
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 149 bits (362), Expect = 1e-35
Identities = 76/231 (32%), Positives = 130/231 (56%), Gaps = 5/231 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R+
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQ--HSHAFLPFSGGSRN 456
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRI 409
C+G+++A + L ++ + + + A ++LK +G +R+
Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPDPTRIPIPI-ARLVLKSKNGIHLRL 506
Score = 54.0 bits (124), Expect = 9e-07
Identities = 32/127 (25%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + N++ R + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 149 bits (360), Expect = 2e-35
Identities = 80/246 (32%), Positives = 136/246 (55%), Gaps = 3/246 (1%)
Query: 162 SDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGH 221
++ V + ++ L +QD +K+R FLD+++ + +T + S+ +++ EV T MF GH
Sbjct: 257 TEKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGH 316
Query: 222 DTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRL 281
DTT++ S++L L + E Q + DE+ E+ GD +T+ QM Y I E LRL
Sbjct: 317 DTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRL 375
Query: 282 YPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENT 341
Y PV I+R L + + + +PAG TV I + +H +P + ++P VFNP F EN+
Sbjct: 376 YAPVVNISRLLDKPITF-PDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENS 434
Query: 342 QNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKR 401
+ H Y++IPFSAG R+C+G+ +A + L +K + S ++ ++LK
Sbjct: 435 EKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVR-QVVLKS 493
Query: 402 YDGFKI 407
+G +
Sbjct: 494 KNGIHV 499
Score = 53.2 bits (122), Expect = 2e-06
Identities = 32/127 (25%), Positives = 67/127 (52%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
++ P F+I+ILK F+ + +E+ + ++ K + + ++ ++S +T+D +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 59 TKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q ++ D Y AV + I +QR H D +FK +S + + + +H T
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTE 258
Query: 118 KVIKKKK 124
KVI+ +K
Sbjct: 259 KVIQDRK 265
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 149 bits (360), Expect = 2e-35
Identities = 76/231 (32%), Positives = 130/231 (56%), Gaps = 5/231 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R+
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRN 456
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRI 409
C+G+++A + L ++ + + + A ++LK +G +R+
Sbjct: 457 CIGKQFAMNQLKVARALTLLRFELLPDPTRTP-IPMARLVLKSKNGIHLRL 506
Score = 52.8 bits (121), Expect = 2e-06
Identities = 31/127 (24%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ + ++S +T+D ++++A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + N++ R + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 149 bits (360), Expect = 2e-35
Identities = 80/246 (32%), Positives = 136/246 (55%), Gaps = 3/246 (1%)
Query: 162 SDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGH 221
++ V + ++ L +QD +K+R FLD+++ + +T + S+ +++ EV T MF GH
Sbjct: 257 TEKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGH 316
Query: 222 DTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRL 281
DTT++ S++L L + E Q + DE+ E+ GD +T+ QM Y I E LRL
Sbjct: 317 DTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRL 375
Query: 282 YPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENT 341
Y PV I+R L + + + +PAG TV I + +H +P + ++P VFNP F EN+
Sbjct: 376 YAPVVNISRLLDKPITF-PDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENS 434
Query: 342 QNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKR 401
+ H Y++IPFSAG R+C+G+ +A + L +K + S ++ ++LK
Sbjct: 435 EKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVR-QVVLKS 493
Query: 402 YDGFKI 407
+G +
Sbjct: 494 KNGIHV 499
Score = 53.2 bits (122), Expect = 2e-06
Identities = 32/127 (25%), Positives = 67/127 (52%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
++ P F+I+ILK F+ + +E+ + ++ K + + ++ ++S +T+D +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 59 TKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q ++ D Y AV + I +QR H D +FK +S + + + +H T
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTE 258
Query: 118 KVIKKKK 124
KVI+ +K
Sbjct: 259 KVIQDRK 265
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 149 bits (360), Expect = 2e-35
Identities = 80/246 (32%), Positives = 136/246 (55%), Gaps = 3/246 (1%)
Query: 162 SDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGH 221
++ V + ++ L +QD +K+R FLD+++ + +T + S+ +++ EV T MF GH
Sbjct: 257 TEKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGH 316
Query: 222 DTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRL 281
DTT++ S++L L + E Q + DE+ E+ GD +T+ QM Y I E LRL
Sbjct: 317 DTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRL 375
Query: 282 YPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENT 341
Y PV I+R L + + + +PAG TV I + +H +P + ++P VFNP F EN+
Sbjct: 376 YAPVVNISRLLDKPITF-PDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENS 434
Query: 342 QNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKR 401
+ H Y++IPFSAG R+C+G+ +A + L +K + S ++ ++LK
Sbjct: 435 EKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVR-QVVLKS 493
Query: 402 YDGFKI 407
+G +
Sbjct: 494 KNGIHV 499
Score = 53.2 bits (122), Expect = 2e-06
Identities = 32/127 (25%), Positives = 67/127 (52%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
++ P F+I+ILK F+ + +E+ + ++ K + + ++ ++S +T+D +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 59 TKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q ++ D Y AV + I +QR H D +FK +S + + + +H T
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTE 258
Query: 118 KVIKKKK 124
KVI+ +K
Sbjct: 259 KVIQDRK 265
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 149 bits (360), Expect = 2e-35
Identities = 80/246 (32%), Positives = 136/246 (55%), Gaps = 3/246 (1%)
Query: 162 SDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGH 221
++ V + ++ L +QD +K+R FLD+++ + +T + S+ +++ EV T MF GH
Sbjct: 257 TEKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGH 316
Query: 222 DTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRL 281
DTT++ S++L L + E Q + DE+ E+ GD +T+ QM Y I E LRL
Sbjct: 317 DTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRL 375
Query: 282 YPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENT 341
Y PV I+R L + + + +PAG TV I + +H +P + ++P VFNP F EN+
Sbjct: 376 YAPVVNISRLLDKPITF-PDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENS 434
Query: 342 QNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKR 401
+ H Y++IPFSAG R+C+G+ +A + L +K + S ++ ++LK
Sbjct: 435 EKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVR-QVVLKS 493
Query: 402 YDGFKI 407
+G +
Sbjct: 494 KNGIHV 499
Score = 53.2 bits (122), Expect = 2e-06
Identities = 32/127 (25%), Positives = 67/127 (52%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
++ P F+I+ILK F+ + +E+ + ++ K + + ++ ++S +T+D +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 59 TKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q ++ D Y AV + I +QR H D +FK +S + + + +H T
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTE 258
Query: 118 KVIKKKK 124
KVI+ +K
Sbjct: 259 KVIQDRK 265
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 148 bits (359), Expect = 3e-35
Identities = 76/231 (32%), Positives = 130/231 (56%), Gaps = 5/231 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R+
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRN 456
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRI 409
C+G+++A + L ++ + + + A ++LK +G +R+
Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPDPTRIPIPI-ARLVLKSKNGIHLRL 506
Score = 54.0 bits (124), Expect = 9e-07
Identities = 32/127 (25%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + N++ R + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 148 bits (359), Expect = 3e-35
Identities = 76/231 (32%), Positives = 130/231 (56%), Gaps = 5/231 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R+
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRN 456
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRI 409
C+G+++A + L ++ + + + A ++LK +G +R+
Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPDPTRIPIPI-ARLVLKSKNGIHLRL 506
Score = 54.0 bits (124), Expect = 9e-07
Identities = 32/127 (25%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + N++ R + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 148 bits (359), Expect = 3e-35
Identities = 76/231 (32%), Positives = 130/231 (56%), Gaps = 5/231 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R+
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRN 456
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRI 409
C+G+++A + L ++ + + + A ++LK +G +R+
Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPDPTRIPIPI-ARLVLKSKNGIHLRL 506
Score = 54.0 bits (124), Expect = 9e-07
Identities = 32/127 (25%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + N++ R + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 148 bits (359), Expect = 3e-35
Identities = 76/231 (32%), Positives = 130/231 (56%), Gaps = 5/231 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R+
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQ--HSHAFLPFSGGSRN 456
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRI 409
C+G+++A + L ++ + + + A ++LK +G +R+
Sbjct: 457 CIGKQFAMNQLKVARALTLLRFELLPDPTRIP-IPMARLVLKSKNGIHLRL 506
Score = 52.4 bits (120), Expect = 3e-06
Identities = 31/127 (24%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ + ++S +T+D ++++A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + +++ R + DAI+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLSSLVFCRMRNAFHENDAIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 148 bits (359), Expect = 3e-35
Identities = 76/231 (32%), Positives = 130/231 (56%), Gaps = 5/231 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R+
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRN 456
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRI 409
C+G+++A + L ++ + + + A ++LK +G +R+
Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPDPTRIPIPI-ARLVLKSKNGIHLRL 506
Score = 54.0 bits (124), Expect = 9e-07
Identities = 32/127 (25%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + N++ R + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 147 bits (355), Expect = 1e-34
Identities = 75/231 (32%), Positives = 130/231 (56%), Gaps = 5/231 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRL+PPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R+
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRN 456
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRI 409
C+G+++A + L ++ + + + A ++LK +G +R+
Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPDPTRIPIPI-ARLVLKSKNGIHLRL 506
Score = 54.0 bits (124), Expect = 9e-07
Identities = 32/127 (25%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + N++ R + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 146 bits (353), Expect = 2e-34
Identities = 70/187 (37%), Positives = 113/187 (60%), Gaps = 4/187 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R+
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQ--HSHAFLPFSGGSRN 456
Query: 359 CVGRKYA 365
C+G+++A
Sbjct: 457 CIGKQFA 463
Score = 54.0 bits (124), Expect = 9e-07
Identities = 32/127 (25%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + N++ R + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 145 bits (351), Expect = 3e-34
Identities = 79/250 (31%), Positives = 135/250 (54%), Gaps = 4/250 (1%)
Query: 162 SDTVFKGYRDDLDFNDEQDVGEKKRLA-FLDLMIESAQNHTCNISDHEIKEEVDTIMFEG 220
+DT+ + + L +QD K++ FLD+++ + + SD ++ EV T + G
Sbjct: 258 TDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAG 317
Query: 221 HDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLR 280
HDT AA S++L L ++ E Q + +E+ I GD +T+ +M Y I E+ R
Sbjct: 318 HDTLAASISWILYCLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCR 376
Query: 281 LYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPEN 340
L P VP+I+R L++ + + +PAG TVV+ + +H +P KNP VF+P F EN
Sbjct: 377 LIPAVPSISRDLSKPLTF-PDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQEN 435
Query: 341 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILK 400
+ RH Y+Y+PFSAG R+C+G+++A + IL +++ T + + ILK
Sbjct: 436 SDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR-PLTFPNHFILK 494
Query: 401 RYDGFKIRIE 410
+G + ++
Sbjct: 495 PKNGMYLHLK 504
Score = 64.1 bits (149), Expect = 9e-10
Identities = 34/128 (26%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 139 LLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS 198
Query: 58 ITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLT 116
Q ++ D YA A+ ++ II R Y + H D IFKL+ + ++L + ++ T
Sbjct: 199 KETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 258
Query: 117 NKVIKKKK 124
+ +I+++K
Sbjct: 259 DTIIQERK 266
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 145 bits (351), Expect = 3e-34
Identities = 79/250 (31%), Positives = 135/250 (54%), Gaps = 4/250 (1%)
Query: 162 SDTVFKGYRDDLDFNDEQDVGEKKRLA-FLDLMIESAQNHTCNISDHEIKEEVDTIMFEG 220
+DT+ + + L +QD K++ FLD+++ + + SD ++ EV T + G
Sbjct: 258 TDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAG 317
Query: 221 HDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLR 280
HDT AA S++L L ++ E Q + +E+ I GD +T+ +M Y I E+ R
Sbjct: 318 HDTLAASISWILYCLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCR 376
Query: 281 LYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPEN 340
L P VP+I+R L++ + + +PAG TVV+ + +H +P KNP VF+P F EN
Sbjct: 377 LIPAVPSISRDLSKPLTF-PDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQEN 435
Query: 341 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILK 400
+ RH Y+Y+PFSAG R+C+G+++A + IL +++ T + + ILK
Sbjct: 436 SDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR-PLTFPNHFILK 494
Query: 401 RYDGFKIRIE 410
+G + ++
Sbjct: 495 PKNGMYLHLK 504
Score = 64.1 bits (149), Expect = 9e-10
Identities = 34/128 (26%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 139 LLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS 198
Query: 58 ITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLT 116
Q ++ D YA A+ ++ II R Y + H D IFKL+ + ++L + ++ T
Sbjct: 199 KETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 258
Query: 117 NKVIKKKK 124
+ +I+++K
Sbjct: 259 DTIIQERK 266
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 145 bits (351), Expect = 3e-34
Identities = 79/250 (31%), Positives = 135/250 (54%), Gaps = 4/250 (1%)
Query: 162 SDTVFKGYRDDLDFNDEQDVGEKKRLA-FLDLMIESAQNHTCNISDHEIKEEVDTIMFEG 220
+DT+ + + L +QD K++ FLD+++ + + SD ++ EV T + G
Sbjct: 258 TDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAG 317
Query: 221 HDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLR 280
HDT AA S++L L ++ E Q + +E+ I GD +T+ +M Y I E+ R
Sbjct: 318 HDTLAASISWILYCLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCR 376
Query: 281 LYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPEN 340
L P VP+I+R L++ + + +PAG TVV+ + +H +P KNP VF+P F EN
Sbjct: 377 LIPAVPSISRDLSKPLTF-PDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQEN 435
Query: 341 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILK 400
+ RH Y+Y+PFSAG R+C+G+++A + IL +++ T + + ILK
Sbjct: 436 SDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR-PLTFPNHFILK 494
Query: 401 RYDGFKIRIE 410
+G + ++
Sbjct: 495 PKNGMYLHLK 504
Score = 64.1 bits (149), Expect = 9e-10
Identities = 34/128 (26%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 139 LLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS 198
Query: 58 ITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLT 116
Q ++ D YA A+ ++ II R Y + H D IFKL+ + ++L + ++ T
Sbjct: 199 KETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 258
Query: 117 NKVIKKKK 124
+ +I+++K
Sbjct: 259 DTIIQERK 266
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 145 bits (351), Expect = 3e-34
Identities = 79/250 (31%), Positives = 135/250 (54%), Gaps = 4/250 (1%)
Query: 162 SDTVFKGYRDDLDFNDEQDVGEKKRLA-FLDLMIESAQNHTCNISDHEIKEEVDTIMFEG 220
+DT+ + + L +QD K++ FLD+++ + + SD ++ EV T + G
Sbjct: 258 TDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAG 317
Query: 221 HDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLR 280
HDT AA S++L L ++ E Q + +E+ I GD +T+ +M Y I E+ R
Sbjct: 318 HDTLAASISWILYCLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCR 376
Query: 281 LYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPEN 340
L P VP+I+R L++ + + +PAG TVV+ + +H +P KNP VF+P F EN
Sbjct: 377 LIPAVPSISRDLSKPLTF-PDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQEN 435
Query: 341 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILK 400
+ RH Y+Y+PFSAG R+C+G+++A + IL +++ T + + ILK
Sbjct: 436 SDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR-PLTFPNHFILK 494
Query: 401 RYDGFKIRIE 410
+G + ++
Sbjct: 495 PKNGMYLHLK 504
Score = 64.1 bits (149), Expect = 9e-10
Identities = 34/128 (26%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 139 LLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS 198
Query: 58 ITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLT 116
Q ++ D YA A+ ++ II R Y + H D IFKL+ + ++L + ++ T
Sbjct: 199 KETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 258
Query: 117 NKVIKKKK 124
+ +I+++K
Sbjct: 259 DTIIQERK 266
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 145 bits (351), Expect = 3e-34
Identities = 79/250 (31%), Positives = 135/250 (54%), Gaps = 4/250 (1%)
Query: 162 SDTVFKGYRDDLDFNDEQDVGEKKRLA-FLDLMIESAQNHTCNISDHEIKEEVDTIMFEG 220
+DT+ + + L +QD K++ FLD+++ + + SD ++ EV T + G
Sbjct: 257 TDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAG 316
Query: 221 HDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLR 280
HDT AA S++L L ++ E Q + +E+ I GD +T+ +M Y I E+ R
Sbjct: 317 HDTLAASISWILYCLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCR 375
Query: 281 LYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPEN 340
L P VP+I+R L++ + + +PAG TVV+ + +H +P KNP VF+P F EN
Sbjct: 376 LIPAVPSISRDLSKPLTF-PDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQEN 434
Query: 341 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILK 400
+ RH Y+Y+PFSAG R+C+G+++A + IL +++ T + + ILK
Sbjct: 435 SDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR-PLTFPNHFILK 493
Query: 401 RYDGFKIRIE 410
+G + ++
Sbjct: 494 PKNGMYLHLK 503
Score = 63.7 bits (148), Expect = 1e-09
Identities = 34/128 (26%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 138 LLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIVMKCAFS 197
Query: 58 ITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLT 116
Q ++ D YA A+ ++ II R Y + H D IFKL+ + ++L + ++ T
Sbjct: 198 KETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 257
Query: 117 NKVIKKKK 124
+ +I+++K
Sbjct: 258 DTIIQERK 265
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 145 bits (351), Expect = 3e-34
Identities = 79/250 (31%), Positives = 135/250 (54%), Gaps = 4/250 (1%)
Query: 162 SDTVFKGYRDDLDFNDEQDVGEKKRLA-FLDLMIESAQNHTCNISDHEIKEEVDTIMFEG 220
+DT+ + + L +QD K++ FLD+++ + + SD ++ EV T + G
Sbjct: 258 TDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAG 317
Query: 221 HDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLR 280
HDT AA S++L L ++ E Q + +E+ I GD +T+ +M Y I E+ R
Sbjct: 318 HDTLAASISWILYCLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCR 376
Query: 281 LYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPEN 340
L P VP+I+R L++ + + +PAG TVV+ + +H +P KNP VF+P F EN
Sbjct: 377 LIPAVPSISRDLSKPLTF-PDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQEN 435
Query: 341 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILK 400
+ RH Y+Y+PFSAG R+C+G+++A + IL +++ T + + ILK
Sbjct: 436 SDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR-PLTFPNHFILK 494
Query: 401 RYDGFKIRIE 410
+G + ++
Sbjct: 495 PKNGMYLHLK 504
Score = 64.1 bits (149), Expect = 9e-10
Identities = 34/128 (26%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 139 LLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS 198
Query: 58 ITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLT 116
Q ++ D YA A+ ++ II R Y + H D IFKL+ + ++L + ++ T
Sbjct: 199 KETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 258
Query: 117 NKVIKKKK 124
+ +I+++K
Sbjct: 259 DTIIQERK 266
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 145 bits (351), Expect = 3e-34
Identities = 79/250 (31%), Positives = 135/250 (54%), Gaps = 4/250 (1%)
Query: 162 SDTVFKGYRDDLDFNDEQDVGEKKRLA-FLDLMIESAQNHTCNISDHEIKEEVDTIMFEG 220
+DT+ + + L +QD K++ FLD+++ + + SD ++ EV T + G
Sbjct: 193 TDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAG 252
Query: 221 HDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLR 280
HDT AA S++L L ++ E Q + +E+ I GD +T+ +M Y I E+ R
Sbjct: 253 HDTLAASISWILYCLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCR 311
Query: 281 LYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPEN 340
L P VP+I+R L++ + + +PAG TVV+ + +H +P KNP VF+P F EN
Sbjct: 312 LIPAVPSISRDLSKPLTF-PDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQEN 370
Query: 341 TQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILK 400
+ RH Y+Y+PFSAG R+C+G+++A + IL +++ T + + ILK
Sbjct: 371 SDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR-PLTFPNHFILK 429
Query: 401 RYDGFKIRIE 410
+G + ++
Sbjct: 430 PKNGMYLHLK 439
Score = 64.1 bits (149), Expect = 9e-10
Identities = 34/128 (26%), Positives = 75/128 (58%), Gaps = 4/128 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 74 LLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS 133
Query: 58 ITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLT 116
Q ++ D YA A+ ++ II R Y + H D IFKL+ + ++L + ++ T
Sbjct: 134 KETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYT 193
Query: 117 NKVIKKKK 124
+ +I+++K
Sbjct: 194 DTIIQERK 201
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 144 bits (350), Expect = 4e-34
Identities = 70/187 (37%), Positives = 113/187 (60%), Gaps = 4/187 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 282 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 341
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 342 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 400
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R+
Sbjct: 401 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRN 457
Query: 359 CVGRKYA 365
C+G+++A
Sbjct: 458 CIGKQFA 464
Score = 50.4 bits (115), Expect = 1e-05
Identities = 33/128 (25%), Positives = 64/128 (50%), Gaps = 4/128 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + N++ R + D I+ LTS + + H T
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLSHQHTR 264
Query: 118 -KVIKKKK 124
KVI+ +K
Sbjct: 265 PKVIQLRK 272
>AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 519
Score = 144 bits (349), Expect = 5e-34
Identities = 75/231 (32%), Positives = 129/231 (55%), Gaps = 5/231 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK N VF+P F P + Q H ++++PFS G R+
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQ--HSHAFLPFSGGSRN 456
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRI 409
C+G+++A + L ++ + + + A ++LK +G +R+
Sbjct: 457 CIGKQFAMNQLKVARALTLLRFELLPDPTRIP-IPMARLVLKSKNGIHLRL 506
Score = 48.0 bits (109), Expect = 6e-05
Identities = 30/127 (23%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D ++++A
Sbjct: 145 MLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + +++ + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 144 bits (349), Expect = 5e-34
Identities = 75/231 (32%), Positives = 129/231 (55%), Gaps = 5/231 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
+ +P G V++ + +H +PK N VF+P F P + Q H ++++PFS G R+
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQ--HSHAFLPFSGGSRN 456
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRI 409
C+G+++A + L ++ + + + A ++LK +G +R+
Sbjct: 457 CIGKQFAMNQLKVARALTLLRFELLPDPTRIPIPI-ARLVLKSKNGIHLRL 506
Score = 48.0 bits (109), Expect = 6e-05
Identities = 30/127 (23%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D ++++A
Sbjct: 145 MLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + +++ + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 142 bits (343), Expect = 3e-33
Identities = 73/228 (32%), Positives = 128/228 (56%), Gaps = 3/228 (1%)
Query: 185 KRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSK 244
K L F+D+++ + +SD +I+ E DT MFEGHDTT++G S++L L + E Q K
Sbjct: 301 KTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEK 360
Query: 245 VYDELFEIF-GDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNY 303
+E+ E+ G + + D Q+ + I ESLR YPPV ++R+ T D+++ +
Sbjct: 361 CREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKL-PDGR 419
Query: 304 IIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 363
IIP G ++ + H +P + V+NP F P+N Q R +Y+PFSAGPR+C+G+
Sbjct: 420 IIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQS 479
Query: 364 YAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
+A + L ++ + + + + + ++IL+ +G +++EP
Sbjct: 480 FAMAELRVVVALTLLRFRLSVDRTR-KVRRKPELILRTENGLWLKVEP 526
Score = 58.0 bits (134), Expect = 6e-08
Identities = 38/178 (21%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH +ILK +M +FN+++ + K L + D+ +++S +T+D L +
Sbjct: 158 LLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFS 217
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S DY A++++ + +R Y++ + D I+ ++ ++ R+ +H T
Sbjct: 218 YNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTT 276
Query: 118 KVIKKKKFMYLQNKEKGIIPPTIEELTKIKDTNDSIMEDSAKTLSDTVFKGYRDDLDF 175
+VI++++ Q + + + D ++ K LSD + D F
Sbjct: 277 EVIQERRRALRQQGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMF 334
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 142 bits (343), Expect = 3e-33
Identities = 73/228 (32%), Positives = 128/228 (56%), Gaps = 3/228 (1%)
Query: 185 KRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSK 244
K L F+D+++ + +SD +I+ E DT MFEGHDTT++G S++L L + E Q K
Sbjct: 301 KTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEK 360
Query: 245 VYDELFEIF-GDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNY 303
+E+ E+ G + + D Q+ + I ESLR YPPV ++R+ T D+++ +
Sbjct: 361 CREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKL-PDGR 419
Query: 304 IIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 363
IIP G ++ + H +P + V+NP F P+N Q R +Y+PFSAGPR+C+G+
Sbjct: 420 IIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQS 479
Query: 364 YAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
+A + L ++ + + + + + ++IL+ +G +++EP
Sbjct: 480 FAMAELRVVVALTLLRFRLSVDRTR-KVRRKPELILRTENGLWLKVEP 526
Score = 58.0 bits (134), Expect = 6e-08
Identities = 38/178 (21%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH +ILK +M +FN+++ + K L + D+ +++S +T+D L +
Sbjct: 158 LLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFS 217
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S DY A++++ + +R Y++ + D I+ ++ ++ R+ +H T
Sbjct: 218 YNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTT 276
Query: 118 KVIKKKKFMYLQNKEKGIIPPTIEELTKIKDTNDSIMEDSAKTLSDTVFKGYRDDLDF 175
+VI++++ Q + + + D ++ K LSD + D F
Sbjct: 277 EVIQERRRALRQQGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMF 334
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 142 bits (343), Expect = 3e-33
Identities = 73/228 (32%), Positives = 128/228 (56%), Gaps = 3/228 (1%)
Query: 185 KRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSK 244
K L F+D+++ + +SD +I+ E DT MFEGHDTT++G S++L L + E Q K
Sbjct: 301 KTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEK 360
Query: 245 VYDELFEIF-GDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNY 303
+E+ E+ G + + D Q+ + I ESLR YPPV ++R+ T D+++ +
Sbjct: 361 CREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKL-PDGR 419
Query: 304 IIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 363
IIP G ++ + H +P + V+NP F P+N Q R +Y+PFSAGPR+C+G+
Sbjct: 420 IIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQS 479
Query: 364 YAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
+A + L ++ + + + + + ++IL+ +G +++EP
Sbjct: 480 FAMAELRVVVALTLLRFRLSVDRTR-KVRRKPELILRTENGLWLKVEP 526
Score = 58.0 bits (134), Expect = 6e-08
Identities = 38/178 (21%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH +ILK +M +FN+++ + K L + D+ +++S +T+D L +
Sbjct: 158 LLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFS 217
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S DY A++++ + +R Y++ + D I+ ++ ++ R+ +H T
Sbjct: 218 YNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTT 276
Query: 118 KVIKKKKFMYLQNKEKGIIPPTIEELTKIKDTNDSIMEDSAKTLSDTVFKGYRDDLDF 175
+VI++++ Q + + + D ++ K LSD + D F
Sbjct: 277 EVIQERRRALRQQGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMF 334
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 142 bits (343), Expect = 3e-33
Identities = 73/228 (32%), Positives = 128/228 (56%), Gaps = 3/228 (1%)
Query: 185 KRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSK 244
K L F+D+++ + +SD +I+ E DT MFEGHDTT++G S++L L + E Q K
Sbjct: 301 KTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEK 360
Query: 245 VYDELFEIF-GDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNY 303
+E+ E+ G + + D Q+ + I ESLR YPPV ++R+ T D+++ +
Sbjct: 361 CREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKL-PDGR 419
Query: 304 IIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 363
IIP G ++ + H +P + V+NP F P+N Q R +Y+PFSAGPR+C+G+
Sbjct: 420 IIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQS 479
Query: 364 YAXXXXXXXXSTILRNYKTTSEISEDQFVLQADIILKRYDGFKIRIEP 411
+A + L ++ + + + + + ++IL+ +G +++EP
Sbjct: 480 FAMAELRVVVALTLLRFRLSVDRTR-KVRRKPELILRTENGLWLKVEP 526
Score = 57.2 bits (132), Expect = 1e-07
Identities = 30/127 (23%), Positives = 69/127 (54%), Gaps = 4/127 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMG 57
++ P FH +ILK +M +FN+++ + K L + D+ +++S +T+D L +
Sbjct: 158 LLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFS 217
Query: 58 ITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
Q+ S DY A++++ + +R Y++ + D I+ ++ ++ R+ +H T
Sbjct: 218 YNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTT 276
Query: 118 KVIKKKK 124
+VI++++
Sbjct: 277 EVIQERR 283
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 133 bits (321), Expect = 1e-30
Identities = 67/179 (37%), Positives = 105/179 (58%), Gaps = 4/179 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPR 357
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSR 455
Score = 54.0 bits (124), Expect = 9e-07
Identities = 32/127 (25%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + N++ R + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 133 bits (321), Expect = 1e-30
Identities = 67/179 (37%), Positives = 105/179 (58%), Gaps = 4/179 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPR 357
+ +P G V++ + +H +PK NP VF+P F P + Q H ++++PFS G R
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSR 455
Score = 54.0 bits (124), Expect = 9e-07
Identities = 32/127 (25%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A
Sbjct: 145 MLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + N++ R + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 129 bits (312), Expect = 2e-29
Identities = 68/202 (33%), Positives = 113/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y+Y PF +GPR+
Sbjct: 384 --NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALMNMKLALIRVLQNF 463
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 129 bits (312), Expect = 2e-29
Identities = 68/202 (33%), Positives = 113/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 264 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 323
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 324 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 382
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y+Y PF +GPR+
Sbjct: 383 --NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRN 440
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 441 CIGMRFALMNMKLALIRVLQNF 462
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 129 bits (312), Expect = 2e-29
Identities = 66/179 (36%), Positives = 104/179 (58%), Gaps = 4/179 (2%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+ + K+ L FLD+++ + + +SD +++ EVDT MFEGHDTTA+G S++L L H
Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
+ Q + +E+ + GD +T+ QM Y I E+LRLYPPVP I R+L+ V
Sbjct: 341 PKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPR 357
+ +P G V++ + +H +PK N VF+P F P + Q H ++++PFS G R
Sbjct: 400 -PDGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQ--HSHAFLPFSGGSR 455
Score = 48.0 bits (109), Expect = 6e-05
Identities = 30/127 (23%), Positives = 65/127 (51%), Gaps = 3/127 (2%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGI 58
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D ++++A
Sbjct: 145 MLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSH 204
Query: 59 TKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTSLFKKQRELLKTIHGLTN 117
+ Q D S Y A+ + +++ + D I+ LTS + + H T+
Sbjct: 205 QGSIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTD 264
Query: 118 KVIKKKK 124
+VI+ +K
Sbjct: 265 QVIQLRK 271
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 128 bits (310), Expect = 3e-29
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALMNMKLALIRVLQNF 463
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 128 bits (310), Expect = 3e-29
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALMNMKLALIRVLQNF 463
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 128 bits (310), Expect = 3e-29
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALMNMKLALIRVLQNF 463
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 128 bits (310), Expect = 3e-29
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALMNMKLALIRVLQNF 463
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 128 bits (310), Expect = 3e-29
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALMNMKLALIRVLQNF 463
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 128 bits (310), Expect = 3e-29
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 115 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 174
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 175 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 233
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 234 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 291
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 292 CIGMRFALMNMKLALIRVLQNF 313
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 128 bits (310), Expect = 3e-29
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 192 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 251
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 252 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 310
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 311 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 368
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 369 CIGMRFALMNMKLALIRVLQNF 390
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 59 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 118
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 128 bits (310), Expect = 3e-29
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALMNMKLALIRVLQNF 463
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 128 bits (310), Expect = 3e-29
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALMNMKLALIRVLQNF 463
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 128 bits (310), Expect = 3e-29
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALMNMKLALIRVLQNF 463
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 128 bits (309), Expect = 4e-29
Identities = 68/202 (33%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALMNMKLALIRVLQNF 463
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 128 bits (309), Expect = 4e-29
Identities = 69/203 (33%), Positives = 113/203 (55%), Gaps = 8/203 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN-----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 237
+K R+ FL LMI+S +N +SD E+ + +F G++TT++ SF++ L
Sbjct: 265 QKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELAT 324
Query: 238 HQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQ 297
H ++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+
Sbjct: 325 HPDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVE 383
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPR 357
I N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR
Sbjct: 384 I--NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 441
Query: 358 SCVGRKYAXXXXXXXXSTILRNY 380
+C+G ++A +L+N+
Sbjct: 442 NCIGMRFALMNMKLALIRVLQNF 464
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 128 bits (309), Expect = 4e-29
Identities = 69/203 (33%), Positives = 113/203 (55%), Gaps = 8/203 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN-----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGI 237
+K R+ FL LMI+S +N +SD E+ + +F G++TT++ SF++ L
Sbjct: 265 QKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELAT 324
Query: 238 HQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQ 297
H ++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+
Sbjct: 325 HPDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVE 383
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPR 357
I N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR
Sbjct: 384 I--NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 441
Query: 358 SCVGRKYAXXXXXXXXSTILRNY 380
+C+G ++A +L+N+
Sbjct: 442 NCIGMRFALMNMKLALIRVLQNF 464
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 126 bits (305), Expect = 1e-28
Identities = 69/218 (31%), Positives = 114/218 (52%), Gaps = 8/218 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ F MI+S + +SD E+ + I+F +DTT+ F++ L H
Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + VT+ +QM+YL+ V+ E+LRL+P V + R +D++I
Sbjct: 325 PDVQQKLQEEIDAVLANKAP-VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V++ + +H DPKY P F P+ F +N + Y YIPF AGPR+
Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQAD 396
C+G ++A L+N+ + E Q L+ D
Sbjct: 442 CIGMRFALTNIKLAVIRALQNF-SFKPCKETQIPLKLD 478
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 126 bits (305), Expect = 1e-28
Identities = 68/202 (33%), Positives = 111/202 (54%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G +TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGCETTSSVLSFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + T+ LQM+YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-PTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +HRDPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALMNMKLALIRVLQNF 463
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 58
+++PTF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 191
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 126 bits (303), Expect = 2e-28
Identities = 67/202 (33%), Positives = 110/202 (54%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q KV E+ + + T+ LQ++YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKVQKEIDTVLPNKAP-PTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +H DPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALVNMKLALVRVLQNF 463
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 126 bits (303), Expect = 2e-28
Identities = 69/218 (31%), Positives = 114/218 (52%), Gaps = 8/218 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ F MI+S + +SD E+ + I+F +DTT+ F++ L H
Sbjct: 155 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 214
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + VT+ +QM+YL+ V+ E+LRL+P V + R +D++I
Sbjct: 215 PDVQQKLQEEIDAVLPNKAP-VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 273
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V++ + +H DPKY P F P+ F +N + Y YIPF AGPR+
Sbjct: 274 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 331
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQAD 396
C+G ++A L+N+ + E Q L+ D
Sbjct: 332 CIGMRFALTNIKLAVIRALQNF-SFKPCKETQIPLKLD 368
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 126 bits (303), Expect = 2e-28
Identities = 67/202 (33%), Positives = 110/202 (54%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q KV E+ + + T+ LQ++YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKVQKEIDTVLPNKAP-PTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +H DPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALVNMKLALVRVLQNF 463
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 126 bits (303), Expect = 2e-28
Identities = 69/218 (31%), Positives = 114/218 (52%), Gaps = 8/218 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ F MI+S + +SD E+ + I+F +DTT+ F++ L H
Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + VT+ +QM+YL+ V+ E+LRL+P V + R +D++I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V++ + +H DPKY P F P+ F +N + Y YIPF AGPR+
Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQAD 396
C+G ++A L+N+ + E Q L+ D
Sbjct: 442 CIGMRFALTNIKLAVIRALQNF-SFKPCKETQIPLKLD 478
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 126 bits (303), Expect = 2e-28
Identities = 69/218 (31%), Positives = 114/218 (52%), Gaps = 8/218 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ F MI+S + +SD E+ + I+F +DTT+ F++ L H
Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + VT+ +QM+YL+ V+ E+LRL+P V + R +D++I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V++ + +H DPKY P F P+ F +N + Y YIPF AGPR+
Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQAD 396
C+G ++A L+N+ + E Q L+ D
Sbjct: 442 CIGMRFALTNIKLAVIRALQNF-SFKPCKETQIPLKLD 478
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 126 bits (303), Expect = 2e-28
Identities = 69/218 (31%), Positives = 114/218 (52%), Gaps = 8/218 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ F MI+S + +SD E+ + I+F +DTT+ F++ L H
Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + VT+ +QM+YL+ V+ E+LRL+P V + R +D++I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V++ + +H DPKY P F P+ F +N + Y YIPF AGPR+
Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQAD 396
C+G ++A L+N+ + E Q L+ D
Sbjct: 442 CIGMRFALTNIKLAVIRALQNF-SFKPCKETQIPLKLD 478
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 126 bits (303), Expect = 2e-28
Identities = 67/202 (33%), Positives = 110/202 (54%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q KV E+ + + T+ LQ++YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKVQKEIDTVLPNKAP-PTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +H DPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALVNMKLALVRVLQNF 463
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 126 bits (303), Expect = 2e-28
Identities = 69/218 (31%), Positives = 114/218 (52%), Gaps = 8/218 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ F MI+S + +SD E+ + I+F +DTT+ F++ L H
Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + VT+ +QM+YL+ V+ E+LRL+P V + R +D++I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V++ + +H DPKY P F P+ F +N + Y YIPF AGPR+
Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQAD 396
C+G ++A L+N+ + E Q L+ D
Sbjct: 442 CIGMRFALTNIKLAVIRALQNF-SFKPCKETQIPLKLD 478
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 126 bits (303), Expect = 2e-28
Identities = 67/202 (33%), Positives = 110/202 (54%), Gaps = 7/202 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ FL LMI+S + +SD E+ + +F G++TT++ SF++ L H
Sbjct: 265 QKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q KV E+ + + T+ LQ++YL+ V+ E+LRL+P + R +DV+I
Sbjct: 325 PDVQQKVQKEIDTVLPNKAP-PTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V+I ++ +H DPKY P F P+ F +N N Y Y PF +GPR+
Sbjct: 384 --NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNY 380
C+G ++A +L+N+
Sbjct: 442 CIGMRFALVNMKLALVRVLQNF 463
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 126 bits (303), Expect = 2e-28
Identities = 69/218 (31%), Positives = 114/218 (52%), Gaps = 8/218 (3%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ F MI+S + +SD E+ + I+F +DTT+ F++ L H
Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + VT+ +QM+YL+ V+ E+LRL+P V + R +D++I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRS 358
N IP G V++ + +H DPKY P F P+ F +N + Y YIPF AGPR+
Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441
Query: 359 CVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQAD 396
C+G ++A L+N+ + E Q L+ D
Sbjct: 442 CIGMRFALTNIKLAVIRALQNF-SFKPCKETQIPLKLD 478
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 124 bits (300), Expect = 4e-28
Identities = 81/246 (32%), Positives = 127/246 (51%), Gaps = 15/246 (6%)
Query: 155 EDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCN----ISDHEIK 210
+D+ LS +V + + L ND+Q K RL FL LMI+S + +SD E+
Sbjct: 243 KDTINFLSKSVNRMKKSRL--NDKQ----KHRLDFLQLMIDSQNSKETESHKALSDLELA 296
Query: 211 EEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKY 270
+ +F G++TT++ SF L L H ++Q K+ E+ + + T+ +QM+Y
Sbjct: 297 AQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAP-PTYDAVVQMEY 355
Query: 271 LERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNV 330
L+ V+ E+LRL+P + R +DV+I N IP GS VVI T+ +H DPKY P
Sbjct: 356 LDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYALHHDPKYWTEPEE 413
Query: 331 FNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQ 390
F P+ F + + Y Y PF GPR+C+G ++A +L+N+ + E Q
Sbjct: 414 FRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF-SFKPCKETQ 471
Query: 391 FVLQAD 396
L+ D
Sbjct: 472 IPLKLD 477
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 124 bits (300), Expect = 4e-28
Identities = 81/246 (32%), Positives = 127/246 (51%), Gaps = 15/246 (6%)
Query: 155 EDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCN----ISDHEIK 210
+D+ LS +V + + L ND+Q K RL FL LMI+S + +SD E+
Sbjct: 243 KDTINFLSKSVNRMKKSRL--NDKQ----KHRLDFLQLMIDSQNSKETESHKALSDLELA 296
Query: 211 EEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKY 270
+ +F G++TT++ SF L L H ++Q K+ E+ + + T+ +QM+Y
Sbjct: 297 AQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAP-PTYDAVVQMEY 355
Query: 271 LERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNV 330
L+ V+ E+LRL+P + R +DV+I N IP GS VVI T+ +H DPKY P
Sbjct: 356 LDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYALHHDPKYWTEPEE 413
Query: 331 FNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQ 390
F P+ F + + Y Y PF GPR+C+G ++A +L+N+ + E Q
Sbjct: 414 FRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF-SFKPCKETQ 471
Query: 391 FVLQAD 396
L+ D
Sbjct: 472 IPLKLD 477
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 124 bits (300), Expect = 4e-28
Identities = 81/246 (32%), Positives = 127/246 (51%), Gaps = 15/246 (6%)
Query: 155 EDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCN----ISDHEIK 210
+D+ LS +V + + L ND+Q K RL FL LMI+S + +SD E+
Sbjct: 243 KDTINFLSKSVNRMKKSRL--NDKQ----KHRLDFLQLMIDSQNSKETESHKALSDLELA 296
Query: 211 EEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKY 270
+ +F G++TT++ SF L L H ++Q K+ E+ + + T+ +QM+Y
Sbjct: 297 AQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAP-PTYDAVVQMEY 355
Query: 271 LERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNV 330
L+ V+ E+LRL+P + R +DV+I N IP GS VVI T+ +H DPKY P
Sbjct: 356 LDMVVNETLRLFPVAIRLERTCMKDVEI--NGVFIPKGSMVVIPTYALHHDPKYWTEPEE 413
Query: 331 FNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQ 390
F P+ F + + Y Y PF GPR+C+G ++A +L+N+ + E Q
Sbjct: 414 FRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF-SFKPCKETQ 471
Query: 391 FVLQAD 396
L+ D
Sbjct: 472 IPLKLD 477
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 124 bits (300), Expect = 4e-28
Identities = 81/246 (32%), Positives = 127/246 (51%), Gaps = 15/246 (6%)
Query: 155 EDSAKTLSDTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCN----ISDHEIK 210
+D+ LS +V + + L ND+Q K RL FL LMI+S + +SD E+
Sbjct: 243 KDTINFLSKSVNRMKKSRL--NDKQ----KHRLDFLQLMIDSQNSKETESHKALSDLELA 296
Query: 211 EEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKY 270
+ +F G++TT++ SF L L H ++Q K+ E+ + + T+ +QM+Y
Sbjct: 297 AQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAP-PTYDAVVQMEY 355
Query: 271 LERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNV 330
L+ V+ E+LRL+P + R +DV+I N IP GS VVI T+ +H DPKY P
Sbjct: 356 LDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYALHHDPKYWTEPEE 413
Query: 331 FNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQ 390
F P+ F + + Y Y PF GPR+C+G ++A +L+N+ + E Q
Sbjct: 414 FRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF-SFKPCKETQ 471
Query: 391 FVLQAD 396
L+ D
Sbjct: 472 IPLKLD 477
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 122 bits (293), Expect = 3e-27
Identities = 69/219 (31%), Positives = 115/219 (52%), Gaps = 9/219 (4%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ F MI+S + +SD E+ + I+F +DTT+ F++ L H
Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + VT+ +QM+YL+ V+ E+LRL+P V + R +D++I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDN-FLPENTQNRHYYSYIPFSAGPR 357
N IP G V++ + +H DPKY P F P++ F +N + Y YIPF AGPR
Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPR 441
Query: 358 SCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQAD 396
+C+G ++A L+N+ + E Q L+ D
Sbjct: 442 NCIGMRFALTNIKLAVIRALQNF-SFKPCKETQIPLKLD 479
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 122 bits (293), Expect = 3e-27
Identities = 69/219 (31%), Positives = 115/219 (52%), Gaps = 9/219 (4%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ F MI+S + +SD E+ + I+F +DTT+ F++ L H
Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + VT+ +QM+YL+ V+ E+LRL+P V + R +D++I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDN-FLPENTQNRHYYSYIPFSAGPR 357
N IP G V++ + +H DPKY P F P++ F +N + Y YIPF AGPR
Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPR 441
Query: 358 SCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVLQAD 396
+C+G ++A L+N+ + E Q L+ D
Sbjct: 442 NCIGMRFALTNIKLAVIRALQNF-SFKPCKETQIPLKLD 479
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 118 bits (283), Expect = 5e-26
Identities = 59/145 (40%), Positives = 87/145 (60%), Gaps = 4/145 (2%)
Query: 215 TIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERV 274
T MFEGHDTTA+G S++L L H + Q + +E+ + GD +T+ QM Y
Sbjct: 1 TFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMC 59
Query: 275 ILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPD 334
I E+LRLYPPVP I+R+L+ V + +P G TV++ + +H +PK NP VF+P
Sbjct: 60 IKEALRLYPPVPGISRELSTPVTF-PDGRSLPKGITVMLSIYGLHHNPKVWPNPEVFDPS 118
Query: 335 NFLPENTQNRHYYSYIPFSAGPRSC 359
F P + Q H ++++PFS G R+C
Sbjct: 119 RFAPGSAQ--HSHAFLPFSGGSRNC 141
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 98.7 bits (235), Expect = 3e-20
Identities = 62/207 (29%), Positives = 103/207 (49%), Gaps = 6/207 (2%)
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADT 265
D + + T GH+T+A +F + L EI +++ E+ E+ G S R + F D
Sbjct: 289 DEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDFEDL 347
Query: 266 LQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
+++YL +V+ ESLRLYPP R L + I + +P + ++ T+ + R Y
Sbjct: 348 GRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI--DGVRVPGNTPLLFSTYVMGRMDTYF 405
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
++P FNPD F P + R ++Y PFS G RSC+G+++A + +L+ +
Sbjct: 406 EDPLTFNPDRFGPGAPKPR--FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRL- 462
Query: 386 ISEDQFVLQADIILKRYDGFKIRIEPR 412
+ +F LQ LK D + PR
Sbjct: 463 VPGQRFGLQEQATLKPLDPVLCTLRPR 489
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 98.7 bits (235), Expect = 3e-20
Identities = 62/207 (29%), Positives = 103/207 (49%), Gaps = 6/207 (2%)
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADT 265
D + + T GH+T+A +F + L EI +++ E+ E+ G S R + F D
Sbjct: 289 DEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDFEDL 347
Query: 266 LQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
+++YL +V+ ESLRLYPP R L + I + +P + ++ T+ + R Y
Sbjct: 348 GRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI--DGVRVPGNTPLLFSTYVMGRMDTYF 405
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
++P FNPD F P + R ++Y PFS G RSC+G+++A + +L+ +
Sbjct: 406 EDPLTFNPDRFGPGAPKPR--FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRL- 462
Query: 386 ISEDQFVLQADIILKRYDGFKIRIEPR 412
+ +F LQ LK D + PR
Sbjct: 463 VPGQRFGLQEQATLKPLDPVLCTLRPR 489
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 97.5 bits (232), Expect = 8e-20
Identities = 56/180 (31%), Positives = 92/180 (51%), Gaps = 6/180 (3%)
Query: 190 LDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDEL 249
L L+IE + + +K+ ++F GH+TTA+ ++ ++ LG++ + KV +EL
Sbjct: 202 LQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEL 261
Query: 250 FE----IFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYII 305
+ D + Q+KY+ VI E+LRL PPVP R + ++ N Y I
Sbjct: 262 KSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL--NGYQI 319
Query: 306 PAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 365
P G V+ H + N FNPD F+ + ++ +S+IPF G RSCVG+++A
Sbjct: 320 PKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFA 379
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 97.5 bits (232), Expect = 8e-20
Identities = 56/180 (31%), Positives = 92/180 (51%), Gaps = 6/180 (3%)
Query: 190 LDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDEL 249
L L+IE + + +K+ ++F GH+TTA+ ++ ++ LG++ + KV +EL
Sbjct: 271 LQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEL 330
Query: 250 FE----IFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYII 305
+ D + Q+KY+ VI E+LRL PPVP R + ++ N Y I
Sbjct: 331 KSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL--NGYQI 388
Query: 306 PAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 365
P G V+ H + N FNPD F+ + ++ +S+IPF G RSCVG+++A
Sbjct: 389 PKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFA 448
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 97.5 bits (232), Expect = 8e-20
Identities = 56/180 (31%), Positives = 92/180 (51%), Gaps = 6/180 (3%)
Query: 190 LDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDEL 249
L L+IE + + +K+ ++F GH+TTA+ ++ ++ LG++ + KV +EL
Sbjct: 271 LQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEL 330
Query: 250 FE----IFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYII 305
+ D + Q+KY+ VI E+LRL PPVP R + ++ N Y I
Sbjct: 331 KSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL--NGYQI 388
Query: 306 PAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYA 365
P G V+ H + N FNPD F+ + ++ +S+IPF G RSCVG+++A
Sbjct: 389 PKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFA 448
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 95.5 bits (227), Expect = 3e-19
Identities = 61/219 (27%), Positives = 104/219 (47%), Gaps = 8/219 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ +D N+ QD + FL M + N + ++ + G +TT+
Sbjct: 244 KEHQESMDMNNPQDFID----CFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTST 299
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL H E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 300 TLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRSHMPYTDAVVHEVQRCIDLLP 358
Query: 287 -AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
++ +T D++ NY+IP G+T++I + D K NP +F+P +FL E +
Sbjct: 359 TSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGDNFKK 416
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
++PFSAG R CVG A ++IL+N+ S
Sbjct: 417 SKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 455
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 95.5 bits (227), Expect = 3e-19
Identities = 61/219 (27%), Positives = 104/219 (47%), Gaps = 8/219 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ +D N+ QD + FL M + N + ++ + G +TT+
Sbjct: 244 KEHQESMDMNNPQDFID----CFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTST 299
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL H E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 300 TLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRSHMPYTDAVVHEVQRCIDLLP 358
Query: 287 -AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
++ +T D++ NY+IP G+T++I + D K NP +F+P +FL E +
Sbjct: 359 TSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGDNFKK 416
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
++PFSAG R CVG A ++IL+N+ S
Sbjct: 417 SKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 455
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 95.1 bits (226), Expect = 4e-19
Identities = 61/219 (27%), Positives = 104/219 (47%), Gaps = 8/219 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ +D N+ QD + FL M + N + ++ + G +TT+
Sbjct: 236 KEHQESMDMNNPQDFID----CFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTST 291
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL H E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 292 TLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRSHMPYTDAVVHEVQRYIDLLP 350
Query: 287 -AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
++ +T D++ NY+IP G+T++I + D K NP +F+P +FL E +
Sbjct: 351 TSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKK 408
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
++PFSAG R CVG A ++IL+N+ S
Sbjct: 409 SKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 447
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 95.1 bits (226), Expect = 4e-19
Identities = 61/219 (27%), Positives = 104/219 (47%), Gaps = 8/219 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ +D N+ QD + FL M + N + ++ + G +TT+
Sbjct: 142 KEHQESMDMNNPQDFID----CFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTST 197
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL H E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 198 TLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRSHMPYTDAVVHEVQRCIDLLP 256
Query: 287 -AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
++ +T D++ NY+IP G+T++I + D K NP +F+P +FL E +
Sbjct: 257 TSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKK 314
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
++PFSAG R CVG A ++IL+N+ S
Sbjct: 315 SKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 353
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 95.1 bits (226), Expect = 4e-19
Identities = 61/219 (27%), Positives = 104/219 (47%), Gaps = 8/219 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ +D N+ QD + FL M + N + ++ + G +TT+
Sbjct: 246 KEHQESMDMNNPQDFID----CFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTST 301
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL H E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 302 TLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRSHMPYTDAVVHEVQRYIDLLP 360
Query: 287 -AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
++ +T D++ NY+IP G+T++I + D K NP +F+P +FL E +
Sbjct: 361 TSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKK 418
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
++PFSAG R CVG A ++IL+N+ S
Sbjct: 419 SKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 457
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 95.1 bits (226), Expect = 4e-19
Identities = 61/219 (27%), Positives = 104/219 (47%), Gaps = 8/219 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ +D N+ QD + FL M + N + ++ + G +TT+
Sbjct: 249 KEHQESMDMNNPQDFID----CFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTST 304
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL H E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 305 TLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRSHMPYTDAVVHEVQRYIDLLP 363
Query: 287 -AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
++ +T D++ NY+IP G+T++I + D K NP +F+P +FL E +
Sbjct: 364 TSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKK 421
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
++PFSAG R CVG A ++IL+N+ S
Sbjct: 422 SKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 95.1 bits (226), Expect = 4e-19
Identities = 61/219 (27%), Positives = 104/219 (47%), Gaps = 8/219 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ +D N+ QD + FL M + N + ++ + G +TT+
Sbjct: 249 KEHQESMDMNNPQDFID----CFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTST 304
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL H E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 305 TLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRSHMPYTDAVVHEVQRYIDLLP 363
Query: 287 -AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
++ +T D++ NY+IP G+T++I + D K NP +F+P +FL E +
Sbjct: 364 TSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKK 421
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
++PFSAG R CVG A ++IL+N+ S
Sbjct: 422 SKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 95.1 bits (226), Expect = 4e-19
Identities = 61/219 (27%), Positives = 104/219 (47%), Gaps = 8/219 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ +D N+ QD + FL M + N + ++ + G +TT+
Sbjct: 249 KEHQESMDMNNPQDFID----CFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTST 304
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL H E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 305 TLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRSHMPYTDAVVHEVQRYIDLLP 363
Query: 287 -AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
++ +T D++ NY+IP G+T++I + D K NP +F+P +FL E +
Sbjct: 364 TSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKK 421
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
++PFSAG R CVG A ++IL+N+ S
Sbjct: 422 SKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 95.1 bits (226), Expect = 4e-19
Identities = 61/219 (27%), Positives = 104/219 (47%), Gaps = 8/219 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ +D N+ QD + FL M + N + ++ + G +TT+
Sbjct: 249 KEHQESMDMNNPQDFID----CFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTST 304
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL H E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 305 TLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRSHMPYTDAVVHEVQRYIDLLP 363
Query: 287 -AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
++ +T D++ NY+IP G+T++I + D K NP +F+P +FL E +
Sbjct: 364 TSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKK 421
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
++PFSAG R CVG A ++IL+N+ S
Sbjct: 422 SKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 330 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 388
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 389 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 446
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 447 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 481
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 263 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 321
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 322 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 379
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 380 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 414
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 93.9 bits (223), Expect = 1e-18
Identities = 49/136 (36%), Positives = 73/136 (53%), Gaps = 4/136 (2%)
Query: 261 TFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHR 320
T+ +QM+YL+ V+ E+LRL+P + R +DV+I N IP GS VVI T+ +H
Sbjct: 17 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYALHH 74
Query: 321 DPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
DPKY P F P+ F + + Y Y PF GPR+C+G ++A +L+N+
Sbjct: 75 DPKYWTEPEEFRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF 133
Query: 381 KTTSEISEDQFVLQAD 396
+ E Q L+ D
Sbjct: 134 -SFKPCKETQIPLKLD 148
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 93.9 bits (223), Expect = 1e-18
Identities = 49/136 (36%), Positives = 73/136 (53%), Gaps = 4/136 (2%)
Query: 261 TFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHR 320
T+ +QM+YL+ V+ E+LRL+P + R +DV+I N IP GS VVI T+ +H
Sbjct: 4 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYALHH 61
Query: 321 DPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
DPKY P F P+ F + + Y Y PF GPR+C+G ++A +L+N+
Sbjct: 62 DPKYWTEPEEFRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF 120
Query: 381 KTTSEISEDQFVLQAD 396
+ E Q L+ D
Sbjct: 121 -SFKPCKETQIPLKLD 135
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHQPFTYLPFGAGPRSCLG 482
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPKTFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 93.9 bits (223), Expect = 1e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 93.5 bits (222), Expect = 1e-18
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 4/201 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y+E VI E R +P ++AR++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP + NP FNP +FL E Q + +++PFS G R+C G A
Sbjct: 387 KGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTSEIS 387
+T+++N++ S S
Sbjct: 447 MELFLFFTTVMQNFRLKSSQS 467
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 93.5 bits (222), Expect = 1e-18
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 4/201 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + G +T + + LL H E+++KV++
Sbjct: 224 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHE 283
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y+E VI E R +P ++AR++ +D + ++ +P
Sbjct: 284 EIDRVIG-KNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLP 340
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP + NP FNP +FL E Q + +++PFS G R+C G A
Sbjct: 341 KGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLAR 400
Query: 367 XXXXXXXSTILRNYKTTSEIS 387
+T+++N++ S S
Sbjct: 401 MELFLFFTTVMQNFRLKSSQS 421
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 93.5 bits (222), Expect = 1e-18
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 4/201 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y+E VI E R +P ++AR++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP + NP FNP +FL E Q + +++PFS G R+C G A
Sbjct: 387 KGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTSEIS 387
+T+++N++ S S
Sbjct: 447 MELFLFFTTVMQNFRLKSSQS 467
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 93.5 bits (222), Expect = 1e-18
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 4/201 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y+E VI E R +P ++AR++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP + NP FNP +FL E Q + +++PFS G R+C G A
Sbjct: 387 KGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTSEIS 387
+T+++N++ S S
Sbjct: 447 MELFLFFTTVMQNFRLKSSQS 467
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 93.5 bits (222), Expect = 1e-18
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 4/201 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y+E VI E R +P ++AR++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP + NP FNP +FL E Q + +++PFS G R+C G A
Sbjct: 387 KGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTSEIS 387
+T+++N++ S S
Sbjct: 447 MELFLFFTTVMQNFRLKSSQS 467
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 93.5 bits (222), Expect = 1e-18
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 4/201 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y+E VI E R +P ++AR++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP + NP FNP +FL E Q + +++PFS G R+C G A
Sbjct: 387 KGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTSEIS 387
+T+++N++ S S
Sbjct: 447 MELFLFFTTVMQNFRLKSSQS 467
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 93.5 bits (222), Expect = 1e-18
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 4/201 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y+E VI E R +P ++AR++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP + NP FNP +FL E Q + +++PFS G R+C G A
Sbjct: 387 KGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTSEIS 387
+T+++N++ S S
Sbjct: 447 MELFLFFTTVMQNFRLKSSQS 467
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 93.5 bits (222), Expect = 1e-18
Identities = 48/155 (30%), Positives = 80/155 (51%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAEDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 93.5 bits (222), Expect = 1e-18
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 4/201 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y+E VI E R +P ++AR++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP + NP FNP +FL E Q + +++PFS G R+C G A
Sbjct: 387 KGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTSEIS 387
+T+++N++ S S
Sbjct: 447 MELFLFFTTVMQNFRLKSSQS 467
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 93.1 bits (221), Expect = 2e-18
Identities = 60/216 (27%), Positives = 103/216 (47%), Gaps = 8/216 (3%)
Query: 173 LDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVL 232
LD N QD + +FL M E +N + + G +T + +
Sbjct: 259 LDPNSPQDFID----SFLIHMQEEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGF 314
Query: 233 CLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARK 291
LL H E+++KV++E+ + G +R F D +M Y+E VI E R +P ++AR+
Sbjct: 315 LLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARR 373
Query: 292 LTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIP 351
+ +D + ++ +P G+ V + RDP + NP FNP +FL + Q + +++P
Sbjct: 374 VKKDTKF--RDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVP 431
Query: 352 FSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEIS 387
FS G R C G A +T+++N++ S S
Sbjct: 432 FSIGKRYCFGEGLARMELFLFFTTVMQNFRLKSSQS 467
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 93.1 bits (221), Expect = 2e-18
Identities = 67/239 (28%), Positives = 110/239 (46%), Gaps = 10/239 (4%)
Query: 149 TNDSIMEDSAKTLS--DTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A T S K ++ LD N+ +D + FL M + N +
Sbjct: 229 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFMD----CFLIKMEQEKDNQKSEFNI 284
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ V + G +TT+ + L LL H E+ +KV +E+ + G R D
Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIG-RHRSPCMQDRS 343
Query: 267 QMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R VP + +T D + NY+IP G+T++ + D K
Sbjct: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKF--RNYLIPKGTTIMALLTSVLHDDKEF 401
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
NPN+F+P +FL +N + ++PFSAG R C G A +TIL+N+ S
Sbjct: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 460
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 92.7 bits (220), Expect = 2e-18
Identities = 67/239 (28%), Positives = 110/239 (46%), Gaps = 10/239 (4%)
Query: 149 TNDSIMEDSAKTLS--DTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A T S K ++ LD N+ +D + FL M + N +
Sbjct: 229 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFID----CFLIKMEQEKDNQKSEFNI 284
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ V + G +TT+ + L LL H E+ +KV +E+ + G R D
Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIG-RHRSPCMQDRS 343
Query: 267 QMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R VP + +T D + NY+IP G+T++ + D K
Sbjct: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKF--RNYLIPKGTTIMALLTSVLHDDKEF 401
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
NPN+F+P +FL +N + ++PFSAG R C G A +TIL+N+ S
Sbjct: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 460
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 92.7 bits (220), Expect = 2e-18
Identities = 66/241 (27%), Positives = 115/241 (47%), Gaps = 10/241 (4%)
Query: 149 TNDSIMEDSAKTLSDTV--FKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A SD + K +++ +D N+ +D + FL M + QN +
Sbjct: 229 THNKLLKNLAFMESDILEKVKEHQESMDINNPRDFID----CFLIKMEKEKQNQQSEFTI 284
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ ++ G +TT+ + L LL H E+ +KV +E+ + G +R D
Sbjct: 285 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRG 343
Query: 267 QMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R +P ++ +T DV+ NY+IP G+T++ + D K
Sbjct: 344 HMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKF--RNYLIPKGTTILTSLTSVLHDNKEF 401
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
NP +F+P +FL E + ++PFSAG R CVG A + IL+N+ S
Sbjct: 402 PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSL 461
Query: 386 I 386
I
Sbjct: 462 I 462
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 92.7 bits (220), Expect = 2e-18
Identities = 55/201 (27%), Positives = 97/201 (48%), Gaps = 4/201 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y+E VI E R +P ++AR++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP + NP FNP +FL + Q + +++PFS G R C G A
Sbjct: 387 KGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTSEIS 387
+T+++N++ S S
Sbjct: 447 MELFLFFTTVMQNFRLKSSQS 467
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 92.7 bits (220), Expect = 2e-18
Identities = 67/239 (28%), Positives = 110/239 (46%), Gaps = 10/239 (4%)
Query: 149 TNDSIMEDSAKTLS--DTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A T S K ++ LD N+ +D + FL M + N +
Sbjct: 229 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFID----CFLIKMEQEKDNQKSEFNI 284
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ V + G +TT+ + L LL H E+ +KV +E+ + G R D
Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIG-RHRSPCMQDRS 343
Query: 267 QMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R VP + +T D + NY+IP G+T++ + D K
Sbjct: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKF--RNYLIPKGTTIMALLTSVLHDDKEF 401
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
NPN+F+P +FL +N + ++PFSAG R C G A +TIL+N+ S
Sbjct: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 460
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 92.7 bits (220), Expect = 2e-18
Identities = 67/239 (28%), Positives = 110/239 (46%), Gaps = 10/239 (4%)
Query: 149 TNDSIMEDSAKTLS--DTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A T S K ++ LD N+ +D + FL M + N +
Sbjct: 229 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFID----CFLIKMEQEKDNQKSEFNI 284
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ V + G +TT+ + L LL H E+ +KV +E+ + G R D
Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIG-RHRSPCMQDRS 343
Query: 267 QMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R VP + +T D + NY+IP G+T++ + D K
Sbjct: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKF--RNYLIPKGTTIMALLTSVLHDDKEF 401
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
NPN+F+P +FL +N + ++PFSAG R C G A +TIL+N+ S
Sbjct: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 460
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 92.7 bits (220), Expect = 2e-18
Identities = 67/239 (28%), Positives = 110/239 (46%), Gaps = 10/239 (4%)
Query: 149 TNDSIMEDSAKTLS--DTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A T S K ++ LD N+ +D + FL M + N +
Sbjct: 229 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFID----CFLIKMEQEKDNQKSEFNI 284
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ V + G +TT+ + L LL H E+ +KV +E+ + G R D
Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIG-RHRSPCMQDRS 343
Query: 267 QMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R VP + +T D + NY+IP G+T++ + D K
Sbjct: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKF--RNYLIPKGTTIMALLTSVLHDDKEF 401
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
NPN+F+P +FL +N + ++PFSAG R C G A +TIL+N+ S
Sbjct: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 460
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 92.7 bits (220), Expect = 2e-18
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF LL + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPENFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 92.7 bits (220), Expect = 2e-18
Identities = 47/155 (30%), Positives = 81/155 (52%), Gaps = 4/155 (2%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI + + G++ SF +L + + Q K+ E+ ++F + F +
Sbjct: 331 EIVGQAFIFLIAGYEIITNTLSFATYVLATNPDCQEKLLREV-DVFKEKHMAPEFCSLEE 389
Query: 268 -MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
+ YL+ VI E+LR+YPP R+ +D +++ IPAG+ + + +H DP++
Sbjct: 390 GLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR--IPAGAVLEMAVGALHHDPEHWP 447
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVG 361
+P FNP+ F E Q ++Y+PF AGPRSC+G
Sbjct: 448 SPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLG 482
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 92.3 bits (219), Expect = 3e-18
Identities = 66/241 (27%), Positives = 115/241 (47%), Gaps = 10/241 (4%)
Query: 149 TNDSIMEDSAKTLSDTV--FKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A SD + K +++ +D N+ +D + FL M + QN +
Sbjct: 207 THNKLLKNLAFMESDILEKVKEHQESMDINNPRDFID----CFLIKMEKEKQNQQSEFTI 262
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ ++ G +TT+ + L LL H E+ +KV +E+ + G +R D
Sbjct: 263 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRG 321
Query: 267 QMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R +P ++ +T DV+ NY+IP G+T++ + D K
Sbjct: 322 HMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKF--RNYLIPKGTTILTSLTSVLHDNKEF 379
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
NP +F+P +FL E + ++PFSAG R CVG A + IL+N+ S
Sbjct: 380 PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSL 439
Query: 386 I 386
I
Sbjct: 440 I 440
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 92.3 bits (219), Expect = 3e-18
Identities = 54/201 (26%), Positives = 95/201 (47%), Gaps = 5/201 (2%)
Query: 165 VFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTT 224
+ K +++ LD + QD + + L + E N + + + + + G DTT
Sbjct: 301 IIKDHQESLDRENPQDFID---MYLLHMEEERKNNSNSSFDEEYLFYIIGDLFIAGTDTT 357
Query: 225 AAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPP 284
+ L + ++ ++Q KV++E+ + G ++R + D QM Y E I+E RL
Sbjct: 358 TNSLLWCLLYMSLNPDVQEKVHEEIERVIG-ANRAPSLTDKAQMPYTEATIMEVQRLTVV 416
Query: 285 VPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNR 344
VP +T + V Y IP G+ ++ + +HRDP + P F P+ FL + Q
Sbjct: 417 VPLAIPHMTSE-NTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLI 475
Query: 345 HYYSYIPFSAGPRSCVGRKYA 365
++IPF G R C+G + A
Sbjct: 476 KKETFIPFGIGKRVCMGEQLA 496
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 92.3 bits (219), Expect = 3e-18
Identities = 66/241 (27%), Positives = 115/241 (47%), Gaps = 10/241 (4%)
Query: 149 TNDSIMEDSAKTLSDTV--FKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A SD + K +++ +D N+ +D + FL M + QN +
Sbjct: 229 THNKLLKNLAFMESDILEKVKEHQESMDINNPRDFID----CFLIKMEKEKQNQQSEFTI 284
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ ++ G +TT+ + L LL H E+ +KV +E+ + G +R D
Sbjct: 285 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRG 343
Query: 267 QMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R +P ++ +T DV+ NY+IP G+T++ + D K
Sbjct: 344 HMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKF--RNYLIPKGTTILTSLTSVLHDNKEF 401
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
NP +F+P +FL E + ++PFSAG R CVG A + IL+N+ S
Sbjct: 402 PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSL 461
Query: 386 I 386
I
Sbjct: 462 I 462
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 92.3 bits (219), Expect = 3e-18
Identities = 54/201 (26%), Positives = 95/201 (47%), Gaps = 5/201 (2%)
Query: 165 VFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTT 224
+ K +++ LD + QD + + L + E N + + + + + G DTT
Sbjct: 301 IIKDHQESLDRENPQDFID---MYLLHMEEERKNNSNSSFDEEYLFYIIGDLFIAGTDTT 357
Query: 225 AAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPP 284
+ L + ++ ++Q KV++E+ + G ++R + D QM Y E I+E RL
Sbjct: 358 TNSLLWCLLYMSLNPDVQEKVHEEIERVIG-ANRAPSLTDKAQMPYTEATIMEVQRLTVV 416
Query: 285 VPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNR 344
VP +T + V Y IP G+ ++ + +HRDP + P F P+ FL + Q
Sbjct: 417 VPLAIPHMTSE-NTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLI 475
Query: 345 HYYSYIPFSAGPRSCVGRKYA 365
++IPF G R C+G + A
Sbjct: 476 KKETFIPFGIGKRVCMGEQLA 496
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 92.3 bits (219), Expect = 3e-18
Identities = 66/241 (27%), Positives = 115/241 (47%), Gaps = 10/241 (4%)
Query: 149 TNDSIMEDSAKTLSDTV--FKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A SD + K +++ +D N+ +D + FL M + QN +
Sbjct: 229 THNKLLKNLAFMESDILEKVKEHQESMDINNPRDFID----CFLIKMEKEKQNQQSEFTI 284
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ ++ G +TT+ + L LL H E+ +KV +E+ + G +R D
Sbjct: 285 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRG 343
Query: 267 QMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R +P ++ +T DV+ NY+IP G+T++ + D K
Sbjct: 344 HMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKF--RNYLIPKGTTILTSLTSVLHDNKEF 401
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
NP +F+P +FL E + ++PFSAG R CVG A + IL+N+ S
Sbjct: 402 PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSL 461
Query: 386 I 386
I
Sbjct: 462 I 462
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 92.3 bits (219), Expect = 3e-18
Identities = 66/241 (27%), Positives = 115/241 (47%), Gaps = 10/241 (4%)
Query: 149 TNDSIMEDSAKTLSDTV--FKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A SD + K +++ +D N+ +D + FL M + QN +
Sbjct: 229 THNKLLKNLAFMESDILEKVKEHQESMDINNPRDFID----CFLIKMEKEKQNQQSEFTI 284
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ ++ G +TT+ + L LL H E+ +KV +E+ + G +R D
Sbjct: 285 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRG 343
Query: 267 QMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R +P ++ +T DV+ NY+IP G+T++ + D K
Sbjct: 344 HMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKF--RNYLIPKGTTILTSLTSVLHDNKEF 401
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
NP +F+P +FL E + ++PFSAG R CVG A + IL+N+ S
Sbjct: 402 PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSL 461
Query: 386 I 386
I
Sbjct: 462 I 462
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 91.9 bits (218), Expect = 4e-18
Identities = 55/201 (27%), Positives = 98/201 (48%), Gaps = 4/201 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + G +T + + LL H E++++V++
Sbjct: 265 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAQVHE 324
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y+E VI E R +P ++AR++ +D + ++ +P
Sbjct: 325 EIDRVIG-KNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLP 381
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP + NP FNP +FL E Q + +++PFS G R+C G A
Sbjct: 382 KGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLAR 441
Query: 367 XXXXXXXSTILRNYKTTSEIS 387
+T+++N++ S S
Sbjct: 442 MELFLFFTTVMQNFRLKSSQS 462
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 91.9 bits (218), Expect = 4e-18
Identities = 63/221 (28%), Positives = 103/221 (46%), Gaps = 8/221 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ LD N+ +D + FL M + N + + V + G +TT+
Sbjct: 129 KEHQESLDMNNPRDFID----CFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTST 184
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL H E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 185 TLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRSHMPYTDAVVHEVQRYIDLIP 243
Query: 287 -AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
++ +T DV+ NY+IP G+T++ + D K NP +F+P +FL E +
Sbjct: 244 TSLPHAVTCDVKF--RNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFKK 301
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
++PFSAG R CVG A + IL+N+ S I
Sbjct: 302 SNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLI 342
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 91.5 bits (217), Expect = 5e-18
Identities = 66/239 (27%), Positives = 110/239 (46%), Gaps = 10/239 (4%)
Query: 149 TNDSIMEDSAKTLS--DTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A T S + ++ LD N+ +D + FL M + N +
Sbjct: 201 THNKVLKNVALTRSYIREKVREHQASLDVNNPRDFID----CFLIKMEQEKDNQKSEFNI 256
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ V + G +TT+ + L LL H E+ +KV +E+ + G R D
Sbjct: 257 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIG-RHRSPCMQDRS 315
Query: 267 QMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R VP + +T D + NY+IP G+T++ + D K
Sbjct: 316 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKF--RNYLIPKGTTIMALLTSVLHDDKEF 373
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
NPN+F+P +FL +N + ++PFSAG R C G A +TIL+N+ S
Sbjct: 374 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 432
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 91.1 bits (216), Expect = 7e-18
Identities = 67/239 (28%), Positives = 109/239 (45%), Gaps = 10/239 (4%)
Query: 149 TNDSIMEDSAKTLS--DTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A T S K ++ LD N+ +D + FL M + N +
Sbjct: 219 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFID----CFLIKMEQEKDNQKSEFNI 274
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ V + G +TT+ + L LL H E+ +KV +E+ + G R D
Sbjct: 275 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIG-RHRSPCMQDRS 333
Query: 267 QMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R VP + +T D + NY+IP G+T++ + D K
Sbjct: 334 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKF--RNYLIPKGTTIMALLTSVLHDDKEF 391
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
NPN+F+P FL +N + ++PFSAG R C G A +TIL+N+ S
Sbjct: 392 PNPNIFDPGLFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 450
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 90.2 bits (214), Expect = 1e-17
Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 4/198 (2%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + F G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y E VI E R +P +A ++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP++ NP FNP +FL + Q + +++PFS G R C G A
Sbjct: 387 KGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTS 384
+TI++N++ S
Sbjct: 447 MELFLFFTTIMQNFRFKS 464
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 90.2 bits (214), Expect = 1e-17
Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 4/198 (2%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + F G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y E VI E R +P +A ++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP++ NP FNP +FL + Q + +++PFS G R C G A
Sbjct: 387 KGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTS 384
+TI++N++ S
Sbjct: 447 MELFLFFTTIMQNFRFKS 464
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 90.2 bits (214), Expect = 1e-17
Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 4/198 (2%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + F G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y E VI E R +P +A ++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP++ NP FNP +FL + Q + +++PFS G R C G A
Sbjct: 387 KGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTS 384
+TI++N++ S
Sbjct: 447 MELFLFFTTIMQNFRFKS 464
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 90.2 bits (214), Expect = 1e-17
Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 4/198 (2%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + F G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y E VI E R +P +A ++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP++ NP FNP +FL + Q + +++PFS G R C G A
Sbjct: 387 KGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTS 384
+TI++N++ S
Sbjct: 447 MELFLFFTTIMQNFRFKS 464
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 90.2 bits (214), Expect = 1e-17
Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 4/198 (2%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + F G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y E VI E R +P +A ++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP++ NP FNP +FL + Q + +++PFS G R C G A
Sbjct: 387 KGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTS 384
+TI++N++ S
Sbjct: 447 MELFLFFTTIMQNFRFKS 464
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 89.8 bits (213), Expect = 2e-17
Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 4/198 (2%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + F G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPELEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y E VI E R +P +A ++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V + RDP++ NP FNP +FL + Q + +++PFS G R C G A
Sbjct: 387 KGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTS 384
+TI++N++ S
Sbjct: 447 MELFLFFTTIMQNFRFKS 464
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 89.4 bits (212), Expect = 2e-17
Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 9/197 (4%)
Query: 189 FLDLMIESAQNHTCN--ISDHEIKEEVDTI--MFEGHDTTAAGSSFVLCLLGIHQEIQSK 244
F+D ++ HT N S HE T+ F G +TT+ + L + ++ EIQ K
Sbjct: 277 FIDAYLKEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEK 336
Query: 245 VYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNY 303
V E+ + G + T A M Y VI E R+ +P + R++T D + Y
Sbjct: 337 VQAEIDRVIGQGQQPSTAARE-SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLA--GY 393
Query: 304 IIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 363
+P G+ ++ +HRDP P+ FNPD+FL EN Q + +++PFS G R+C+G +
Sbjct: 394 HLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFKKREAFMPFSIGKRACLGEQ 452
Query: 364 YAXXXXXXXXSTILRNY 380
A +++++ +
Sbjct: 453 LARTELFIFFTSLMQKF 469
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 89.4 bits (212), Expect = 2e-17
Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 9/197 (4%)
Query: 189 FLDLMIESAQNHTCN--ISDHEIKEEVDTI--MFEGHDTTAAGSSFVLCLLGIHQEIQSK 244
F+D ++ HT N S HE T+ F G +TT+ + L + ++ EIQ K
Sbjct: 277 FIDAYLKEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEK 336
Query: 245 VYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNY 303
V E+ + G + T A M Y VI E R+ +P + R++T D + Y
Sbjct: 337 VQAEIDRVIGQGQQPSTAARE-SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLA--GY 393
Query: 304 IIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 363
+P G+ ++ +HRDP P+ FNPD+FL EN Q + +++PFS G R+C+G +
Sbjct: 394 HLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFKKREAFMPFSIGKRACLGEQ 452
Query: 364 YAXXXXXXXXSTILRNY 380
A +++++ +
Sbjct: 453 LARTELFIFFTSLMQKF 469
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 89.4 bits (212), Expect = 2e-17
Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 9/197 (4%)
Query: 189 FLDLMIESAQNHTCN--ISDHEIKEEVDTI--MFEGHDTTAAGSSFVLCLLGIHQEIQSK 244
F+D ++ HT N S HE T+ F G +TT+ + L + ++ EIQ K
Sbjct: 277 FIDAYLKEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEK 336
Query: 245 VYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNY 303
V E+ + G + T A M Y VI E R+ +P + R++T D + Y
Sbjct: 337 VQAEIDRVIGQGQQPSTAARE-SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLA--GY 393
Query: 304 IIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 363
+P G+ ++ +HRDP P+ FNPD+FL EN Q + +++PFS G R+C+G +
Sbjct: 394 HLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFKKREAFMPFSIGKRACLGEQ 452
Query: 364 YAXXXXXXXXSTILRNY 380
A +++++ +
Sbjct: 453 LARTELFIFFTSLMQKF 469
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 89.4 bits (212), Expect = 2e-17
Identities = 49/156 (31%), Positives = 84/156 (53%), Gaps = 7/156 (4%)
Query: 183 EKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIH 238
+K R+ F MI+S + +SD E+ + I+F +DTT+ F++ L H
Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324
Query: 239 QEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQI 298
++Q K+ +E+ + + VT+ +QM+YL+ V+ E+LRL+P V + R +D++I
Sbjct: 325 PDVQQKLQEEIDAVLPNKAP-VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383
Query: 299 VTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPD 334
N IP G V++ + +H DPKY P F P+
Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPE 417
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 89.4 bits (212), Expect = 2e-17
Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 9/197 (4%)
Query: 189 FLDLMIESAQNHTCN--ISDHEIKEEVDTI--MFEGHDTTAAGSSFVLCLLGIHQEIQSK 244
F+D ++ HT N S HE T+ F G +TT+ + L + ++ EIQ K
Sbjct: 277 FIDAYLKEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEK 336
Query: 245 VYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNY 303
V E+ + G + T A M Y VI E R+ +P + R++T D + Y
Sbjct: 337 VQAEIDRVIGQGQQPSTAARE-SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLA--GY 393
Query: 304 IIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 363
+P G+ ++ +HRDP P+ FNPD+FL EN Q + +++PFS G R+C+G +
Sbjct: 394 HLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFKKREAFMPFSIGKRACLGEQ 452
Query: 364 YAXXXXXXXXSTILRNY 380
A +++++ +
Sbjct: 453 LARTELFIFFTSLMQKF 469
>AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
Homo sapiens cholesterol 24-hydroxylase mRNA. ).
Length = 337
Score = 89.0 bits (211), Expect = 3e-17
Identities = 64/207 (30%), Positives = 100/207 (48%), Gaps = 16/207 (7%)
Query: 206 DHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADT 265
D + + T GH+T+A +F + L EI +++ E+ E+ G S R + F D
Sbjct: 136 DEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDFEDL 194
Query: 266 LQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
+++YL +V+ ESLRLYPP R L + +I ST V+G R Y
Sbjct: 195 GRLQYLSQVLKESLRLYPPAWGTFRLLEEET-------LIDGFSTYVMG-----RMDTYF 242
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
++P FNPD F P + R ++Y PFS G RSC+G+++A + +L+ +
Sbjct: 243 EDPLTFNPDRFGPGAPKPR--FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRL- 299
Query: 386 ISEDQFVLQADIILKRYDGFKIRIEPR 412
+ +F LQ LK D + PR
Sbjct: 300 VPGQRFGLQEQATLKPLDPVLCTLRPR 326
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 89.0 bits (211), Expect = 3e-17
Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 9/197 (4%)
Query: 189 FLDLMIESAQNHTCN--ISDHEIKEEVDTI--MFEGHDTTAAGSSFVLCLLGIHQEIQSK 244
F+D ++ HT N S HE T+ F G +TT+ + L + ++ EIQ K
Sbjct: 277 FIDAYLKEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEK 336
Query: 245 VYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNY 303
V E+ + G + T A M Y VI E R+ +P + R++T D + Y
Sbjct: 337 VQVEIDRVIGQGQQPSTAARE-SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLA--GY 393
Query: 304 IIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRK 363
+P G+ ++ +HRDP P+ FNPD+FL EN Q + +++PFS G R+C+G +
Sbjct: 394 HLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFKKREAFMPFSIGKRACLGEQ 452
Query: 364 YAXXXXXXXXSTILRNY 380
A +++++ +
Sbjct: 453 LARTELFIFFTSLMQKF 469
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 88.6 bits (210), Expect = 4e-17
Identities = 59/216 (27%), Positives = 103/216 (47%), Gaps = 8/216 (3%)
Query: 173 LDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVL 232
LD N QD + +FL M E +N + + G +T + +
Sbjct: 259 LDPNSPQDFID----SFLIHMQEEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGF 314
Query: 233 CLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARK 291
LL H E+++KV++E+ + G +R F D +M Y+E VI E R +P ++AR+
Sbjct: 315 LLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARR 373
Query: 292 LTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIP 351
+ +D + ++ +P G+ V + RD ++ NP FNP +FL E Q + +++P
Sbjct: 374 VKKDTKF--RDFFLPKGTEVFPMLGSVLRDLRFFSNPRDFNPQHFLGEKGQFKKRDAFVP 431
Query: 352 FSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEIS 387
FS R+C G A +T+++N++ S S
Sbjct: 432 FSIRKRNCFGEGLARMELFLFFTTVMQNFRLKSSQS 467
>BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein.
Length = 280
Score = 88.6 bits (210), Expect = 4e-17
Identities = 48/160 (30%), Positives = 87/160 (54%), Gaps = 7/160 (4%)
Query: 179 QDVGEKKRLAFLDLMIESAQNHTCN----ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCL 234
+++G + R+ F +I+S + +SD E+ + I+F +DTT+ F++
Sbjct: 121 EELGLQHRVDFFQQIIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYE 180
Query: 235 LGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTR 294
L H ++Q K+ +E+ + + VT+ +QM+YL+ V+ E+LRL+P V + R +
Sbjct: 181 LATHPDVQQKLQEEIDAVLPNKAP-VTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKK 239
Query: 295 DVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPD 334
D++I N IP G V++ + +H DPKY P F P+
Sbjct: 240 DIEI--NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPE 277
>X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C
protein.
Length = 356
Score = 88.2 bits (209), Expect = 5e-17
Identities = 65/241 (26%), Positives = 112/241 (46%), Gaps = 10/241 (4%)
Query: 149 TNDSIMEDSAKTLS--DTVFKGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISD 206
T++ ++++ A T S K ++ LD N+ +D + FL M + N +
Sbjct: 95 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFID----CFLIKMEQEKDNQKSEFTI 150
Query: 207 HEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL 266
+ ++ G +TT+ + L LL H E+ +KV +E+ + G +R D
Sbjct: 151 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRG 209
Query: 267 QMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYH 325
M Y + V+ E R +P ++ +T D++ NY+IP G+T++ + D K
Sbjct: 210 HMPYTDAVVHEVQRYIDLIPTSLPHAVTCDIKF--RNYLIPKGTTILTSLTSVLHDNKEF 267
Query: 326 KNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
NP +F+P +FL E + ++PFSAG R CVG A + IL+N+ S
Sbjct: 268 PNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSL 327
Query: 386 I 386
I
Sbjct: 328 I 328
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 87.0 bits (206), Expect = 1e-16
Identities = 54/201 (26%), Positives = 96/201 (47%), Gaps = 4/201 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLHYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y+E VI E R +P ++AR++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G V + RD ++ NP FNP +FL E Q + +++PFS R+C G A
Sbjct: 387 KGIEVFPMLGSVLRDLRFFSNPRDFNPQHFLGEKGQFKKRDAFVPFSIRKRNCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTSEIS 387
+T+++N++ S S
Sbjct: 447 MELFLFFTTVMQNFRLKSSQS 467
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 87.0 bits (206), Expect = 1e-16
Identities = 65/235 (27%), Positives = 106/235 (45%), Gaps = 7/235 (2%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
AFL M + QN ++ + V ++F G T + + L LL + +Q V +
Sbjct: 271 AFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVRE 330
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
EL G + + + D ++ Y + V+ E+ RL VP I R L R + Y +P
Sbjct: 331 ELNRELG-AGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRF--RGYTLP 387
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V I DP K+P FNPD FL + + R + +++PFS G R C+G A
Sbjct: 388 QGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAK 447
Query: 367 XXXXXXXSTILRNYKTTSEISEDQFVLQADI--ILKRYDGFKIRIEPRNKNHSNT 419
+TIL+ + S D L+ + + F++++ P + HS T
Sbjct: 448 AELFLFFTTILQAFSLESPCPPDTLSLKPTVSGLFNIPPAFQLQVRPTDL-HSTT 501
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 87.0 bits (206), Expect = 1e-16
Identities = 65/235 (27%), Positives = 106/235 (45%), Gaps = 7/235 (2%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
AFL M + QN ++ + V ++F G T + + L LL + +Q V +
Sbjct: 271 AFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVRE 330
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
EL G + + + D ++ Y + V+ E+ RL VP I R L R + Y +P
Sbjct: 331 ELNRELG-AGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRF--RGYTLP 387
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V I DP K+P FNPD FL + + R + +++PFS G R C+G A
Sbjct: 388 QGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAK 447
Query: 367 XXXXXXXSTILRNYKTTSEISEDQFVLQADI--ILKRYDGFKIRIEPRNKNHSNT 419
+TIL+ + S D L+ + + F++++ P + HS T
Sbjct: 448 AELFLFFTTILQAFSLESPCPPDTLSLKPTVSGLFNIPPAFQLQVRPTDL-HSTT 501
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 87.0 bits (206), Expect = 1e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 4/174 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL-QMKYL 271
V ++ G DT + S+ L L H E+Q+ ++ E+ A L Q+ L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 272 ERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
+ V+ E LRLYP VP +R +D+ + +YIIP + V + + RDP PN F
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFPEPNSF 428
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
P +L E H ++ +PF G RSC+GR+ A + IL +++ E
Sbjct: 429 RPARWLGEG-PTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPE 481
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 87.0 bits (206), Expect = 1e-16
Identities = 65/235 (27%), Positives = 106/235 (45%), Gaps = 7/235 (2%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
AFL M + QN ++ + V ++F G T + + L LL + +Q V +
Sbjct: 271 AFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVRE 330
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
EL G + + + D ++ Y + V+ E+ RL VP I R L R + Y +P
Sbjct: 331 ELNRELG-AGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRF--RGYTLP 387
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V I DP K+P FNPD FL + + R + +++PFS G R C+G A
Sbjct: 388 QGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAK 447
Query: 367 XXXXXXXSTILRNYKTTSEISEDQFVLQADI--ILKRYDGFKIRIEPRNKNHSNT 419
+TIL+ + S D L+ + + F++++ P + HS T
Sbjct: 448 AELFLFFTTILQAFSLESPCPPDTLSLKPTVSGLFNIPPAFQLQVRPTDL-HSTT 501
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 87.0 bits (206), Expect = 1e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 4/174 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL-QMKYL 271
V ++ G DT + S+ L L H E+Q+ ++ E+ A L Q+ L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 272 ERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
+ V+ E LRLYP VP +R +D+ + +YIIP + V + + RDP PN F
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFPEPNSF 428
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
P +L E H ++ +PF G RSC+GR+ A + IL +++ E
Sbjct: 429 RPARWLGEG-PTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPE 481
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 87.0 bits (206), Expect = 1e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 4/174 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL-QMKYL 271
V ++ G DT + S+ L L H E+Q+ ++ E+ A L Q+ L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 272 ERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
+ V+ E LRLYP VP +R +D+ + +YIIP + V + + RDP PN F
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFPEPNSF 428
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
P +L E H ++ +PF G RSC+GR+ A + IL +++ E
Sbjct: 429 RPARWLGEG-PTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPE 481
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 87.0 bits (206), Expect = 1e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 4/174 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL-QMKYL 271
V ++ G DT + S+ L L H E+Q+ ++ E+ A L Q+ L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 272 ERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
+ V+ E LRLYP VP +R +D+ + +YIIP + V + + RDP PN F
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFPEPNSF 428
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
P +L E H ++ +PF G RSC+GR+ A + IL +++ E
Sbjct: 429 RPARWLGEG-PTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPE 481
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 87.0 bits (206), Expect = 1e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 4/174 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL-QMKYL 271
V ++ G DT + S+ L L H E+Q+ ++ E+ A L Q+ L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 272 ERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
+ V+ E LRLYP VP +R +D+ + +YIIP + V + + RDP PN F
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFPEPNSF 428
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
P +L E H ++ +PF G RSC+GR+ A + IL +++ E
Sbjct: 429 RPARWLGEG-PTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPE 481
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 87.0 bits (206), Expect = 1e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 4/174 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL-QMKYL 271
V ++ G DT + S+ L L H E+Q+ ++ E+ A L Q+ L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 272 ERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
+ V+ E LRLYP VP +R +D+ + +YIIP + V + + RDP PN F
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFPEPNSF 428
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
P +L E H ++ +PF G RSC+GR+ A + IL +++ E
Sbjct: 429 RPARWLGEG-PTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPE 481
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 87.0 bits (206), Expect = 1e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 4/174 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL-QMKYL 271
V ++ G DT + S+ L L H E+Q+ ++ E+ A L Q+ L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 272 ERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
+ V+ E LRLYP VP +R +D+ + +YIIP + V + + RDP PN F
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFPEPNSF 428
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
P +L E H ++ +PF G RSC+GR+ A + IL +++ E
Sbjct: 429 RPARWLGEG-PTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPE 481
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 87.0 bits (206), Expect = 1e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 4/174 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL-QMKYL 271
V ++ G DT + S+ L L H E+Q+ ++ E+ A L Q+ L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 272 ERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
+ V+ E LRLYP VP +R +D+ + +YIIP + V + + RDP PN F
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFPEPNSF 428
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
P +L E H ++ +PF G RSC+GR+ A + IL +++ E
Sbjct: 429 RPARWLGEG-PTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPE 481
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 87.0 bits (206), Expect = 1e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 4/174 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTL-QMKYL 271
V ++ G DT + S+ L L H E+Q+ ++ E+ A L Q+ L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 272 ERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
+ V+ E LRLYP VP +R +D+ + +YIIP + V + + RDP PN F
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFPEPNSF 428
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSE 385
P +L E H ++ +PF G RSC+GR+ A + IL +++ E
Sbjct: 429 RPARWLGEG-PTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPE 481
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 86.6 bits (205), Expect = 1e-16
Identities = 59/221 (26%), Positives = 104/221 (47%), Gaps = 8/221 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ LD N +D + FL M + N + + V + G +TT+
Sbjct: 249 KEHQESLDMNSARDFID----CFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTST 304
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL + E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 305 TLRYGLLLLLKYPEVTAKVQEEIECVVG-RNRSPCMQDRSHMPYTDAVVHEIQRYIDLLP 363
Query: 287 A-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
+ +T DV+ NY+IP G+T++ + + K NP +F+P +FL ++ +
Sbjct: 364 TNLPHAVTCDVKF--KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKK 421
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
++PFSAG R C+G A +TIL+N+ S++
Sbjct: 422 SDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 86.6 bits (205), Expect = 1e-16
Identities = 59/221 (26%), Positives = 104/221 (47%), Gaps = 8/221 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ LD N +D + FL M + N + + V + G +TT+
Sbjct: 249 KEHQESLDMNSARDFID----CFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTST 304
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL + E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 305 TLRYGLLLLLKYPEVTAKVQEEIECVVG-RNRSPCMQDRSHMPYTDAVVHEIQRYIDLLP 363
Query: 287 A-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
+ +T DV+ NY+IP G+T++ + + K NP +F+P +FL ++ +
Sbjct: 364 TNLPHAVTCDVKF--KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKK 421
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
++PFSAG R C+G A +TIL+N+ S++
Sbjct: 422 SDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 86.6 bits (205), Expect = 1e-16
Identities = 59/221 (26%), Positives = 104/221 (47%), Gaps = 8/221 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ LD N +D + FL M + N + + V + G +TT+
Sbjct: 249 KEHQESLDMNSARDFID----CFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTST 304
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL + E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 305 TLRYGLLLLLKYPEVTAKVQEEIECVVG-RNRSPCMQDRSHMPYTDAVVHEIQRYIDLLP 363
Query: 287 A-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
+ +T DV+ NY+IP G+T++ + + K NP +F+P +FL ++ +
Sbjct: 364 TNLPHAVTCDVKF--KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKK 421
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
++PFSAG R C+G A +TIL+N+ S++
Sbjct: 422 SDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 86.6 bits (205), Expect = 1e-16
Identities = 59/221 (26%), Positives = 104/221 (47%), Gaps = 8/221 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ LD N +D + FL M + N + + V + G +TT+
Sbjct: 249 KEHQESLDMNSARDFID----CFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTST 304
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL + E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 305 TLRYGLLLLLKYPEVTAKVQEEIECVVG-RNRSPCMQDRSHMPYTDAVVHEIQRYIDLLP 363
Query: 287 A-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
+ +T DV+ NY+IP G+T++ + + K NP +F+P +FL ++ +
Sbjct: 364 TNLPHAVTCDVKF--KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKK 421
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
++PFSAG R C+G A +TIL+N+ S++
Sbjct: 422 SDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 86.6 bits (205), Expect = 1e-16
Identities = 59/221 (26%), Positives = 104/221 (47%), Gaps = 8/221 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ LD N +D + FL M + N + + V + G +TT+
Sbjct: 249 KEHQESLDMNSARDFID----CFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTST 304
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL + E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 305 TLRYGLLLLLKYPEVTAKVQEEIECVVG-RNRSPCMQDRSHMPYTDAVVHEIQRYIDLLP 363
Query: 287 A-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
+ +T DV+ NY+IP G+T++ + + K NP +F+P +FL ++ +
Sbjct: 364 TNLPHAVTCDVKF--KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKK 421
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
++PFSAG R C+G A +TIL+N+ S++
Sbjct: 422 SDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 421
Score = 86.6 bits (205), Expect = 1e-16
Identities = 45/143 (31%), Positives = 77/143 (53%), Gaps = 4/143 (2%)
Query: 267 QMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHK 326
QM Y I E+LRLYPPVP I R+L+ V + +P G V++ + +H +PK
Sbjct: 270 QMPYTTMCIKEALRLYPPVPGIGRELSTPVTF-PDGRSLPKGIMVLLSIYGLHHNPKVWP 328
Query: 327 NPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
N VF+P F P + Q H ++++PFS G R+C+G+++A + L ++ +
Sbjct: 329 NLEVFDPSRFAPGSAQ--HSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDP 386
Query: 387 SEDQFVLQADIILKRYDGFKIRI 409
+ + A ++LK +G +R+
Sbjct: 387 TRIP-IPMARLVLKSKNGIHLRL 408
Score = 34.7 bits (76), Expect = 0.62
Identities = 15/57 (26%), Positives = 36/57 (63%), Gaps = 2/57 (3%)
Query: 1 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETA 55
M+ P FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D ++++A
Sbjct: 145 MLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSA 201
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 86.2 bits (204), Expect = 2e-16
Identities = 52/193 (26%), Positives = 91/193 (47%), Gaps = 2/193 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
A+LD M + + + S + V ++ G +TT + + + ++ IQ +V
Sbjct: 279 AYLDEMDQGKNDPSSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQK 338
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPA 307
E+ I G + + ++ D +M Y E V+ E LR VP T + +V Y IP
Sbjct: 339 EIDLIMGPNGK-PSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVV-RGYSIPK 396
Query: 308 GSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXX 367
G+TV+ + +H D KY ++P VF+P+ FL + + +PFS G R C+G A
Sbjct: 397 GTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARM 456
Query: 368 XXXXXXSTILRNY 380
+ +L+ +
Sbjct: 457 EMFLFFTALLQRF 469
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 86.2 bits (204), Expect = 2e-16
Identities = 52/193 (26%), Positives = 91/193 (47%), Gaps = 2/193 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
A+LD M + + + S + V ++ G +TT + + + ++ IQ +V
Sbjct: 279 AYLDEMDQGKNDPSSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQK 338
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPA 307
E+ I G + + ++ D +M Y E V+ E LR VP T + +V Y IP
Sbjct: 339 EIDLIMGPNGK-PSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVV-RGYSIPK 396
Query: 308 GSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXX 367
G+TV+ + +H D KY ++P VF+P+ FL + + +PFS G R C+G A
Sbjct: 397 GTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARM 456
Query: 368 XXXXXXSTILRNY 380
+ +L+ +
Sbjct: 457 EMFLFFTALLQRF 469
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 86.2 bits (204), Expect = 2e-16
Identities = 52/193 (26%), Positives = 91/193 (47%), Gaps = 2/193 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
A+LD M + + + S + V ++ G +TT + + + ++ IQ +V
Sbjct: 279 AYLDEMDQGKNDPSSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQK 338
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPA 307
E+ I G + + ++ D +M Y E V+ E LR VP T + +V Y IP
Sbjct: 339 EIDLIMGPNGK-PSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVV-RGYSIPK 396
Query: 308 GSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXX 367
G+TV+ + +H D KY ++P VF+P+ FL + + +PFS G R C+G A
Sbjct: 397 GTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARM 456
Query: 368 XXXXXXSTILRNY 380
+ +L+ +
Sbjct: 457 EMFLFFTALLQRF 469
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 86.2 bits (204), Expect = 2e-16
Identities = 59/221 (26%), Positives = 104/221 (47%), Gaps = 8/221 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ LD N +D + FL M + N + + V + G +TT+
Sbjct: 249 KEHQESLDMNSARDFID----CFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTST 304
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL + E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 305 TLRYGLLLLLKYPEVTAKVQEEIECVVG-RNRSPCMQDRSHMPYTDAVVHEIQRYIDLLP 363
Query: 287 A-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
+ +T DV+ NY+IP G+T++ + + K NP +F+P +FL ++ +
Sbjct: 364 TNLPHAVTCDVKF--KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKK 421
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
++PFSAG R C+G A +TIL+N+ S++
Sbjct: 422 SDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSKV 462
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 85.8 bits (203), Expect = 3e-16
Identities = 59/221 (26%), Positives = 103/221 (46%), Gaps = 8/221 (3%)
Query: 167 KGYRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAA 226
K +++ LD N +D + FL M + N + + V + G +TT+
Sbjct: 249 KEHQESLDMNSARDFID----CFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTST 304
Query: 227 GSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP 286
+ L LL + E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 305 TLRYGLLLLLKYPEVTAKVQEEIECVVG-RNRSPCMQDRSHMPYTDAVVHEIQRYIDLLP 363
Query: 287 A-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH 345
+ +T DV+ NY+IP G T++ + + K NP +F+P +FL ++ +
Sbjct: 364 TNLPHAVTCDVKF--KNYLIPKGMTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKK 421
Query: 346 YYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
++PFSAG R C+G A +TIL+N+ S++
Sbjct: 422 SDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120
AA) protein.
Length = 210
Score = 85.4 bits (202), Expect = 3e-16
Identities = 53/173 (30%), Positives = 83/173 (47%), Gaps = 4/173 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLE 272
V + G +TT+ + L LL H E+ +KV +E+ + G R D M Y +
Sbjct: 11 VADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIG-RHRSPCMQDRSHMPYTD 69
Query: 273 RVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
V+ E R VP + +T D + NY+IP G+T++ + D + NPN+F
Sbjct: 70 AVVHEIQRYSDLVPTGVPHAVTTDTKF--RNYLIPKGTTIMALLTSVLHDDREFPNPNIF 127
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
+P +FL +N + ++PFSAG R C G A +TIL+N+ S
Sbjct: 128 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 180
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 85.0 bits (201), Expect = 4e-16
Identities = 65/215 (30%), Positives = 104/215 (48%), Gaps = 11/215 (5%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+SD+ I + I G +TT + + L L + +++ K+Y+E+ + G S R T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFS-RTPTIS 345
Query: 264 DTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDP 322
D ++ LE I E LRL P P I K D I + + G+ V+I + +H +
Sbjct: 346 DRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSI--GEFAVDKGTEVIINLWALHHNE 403
Query: 323 KYHKNPNVFNPDNFL-PENTQN-RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
K P+ F P+ FL P TQ SY+PF AGPRSC+G A + +L+ +
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
Query: 381 KTTSEISEDQFVLQADIILK---RYDGFKIRIEPR 412
E+ +D + + I K D FK++I+ R
Sbjct: 464 DL--EVPDDGQLPSLEGIPKVVFLIDSFKVKIKVR 496
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 85.0 bits (201), Expect = 4e-16
Identities = 65/215 (30%), Positives = 104/215 (48%), Gaps = 11/215 (5%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+SD+ I + I G +TT + + L L + +++ K+Y+E+ + G S R T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFS-RTPTIS 345
Query: 264 DTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDP 322
D ++ LE I E LRL P P I K D I + + G+ V+I + +H +
Sbjct: 346 DRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSI--GEFAVDKGTEVIINLWALHHNE 403
Query: 323 KYHKNPNVFNPDNFL-PENTQN-RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
K P+ F P+ FL P TQ SY+PF AGPRSC+G A + +L+ +
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
Query: 381 KTTSEISEDQFVLQADIILK---RYDGFKIRIEPR 412
E+ +D + + I K D FK++I+ R
Sbjct: 464 DL--EVPDDGQLPSLEGIPKVVFLIDSFKVKIKVR 496
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 85.0 bits (201), Expect = 4e-16
Identities = 65/215 (30%), Positives = 104/215 (48%), Gaps = 11/215 (5%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+SD+ I + I G +TT + + L L + +++ K+Y+E+ + G S R T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFS-RTPTIS 345
Query: 264 DTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDP 322
D ++ LE I E LRL P P I K D I + + G+ V+I + +H +
Sbjct: 346 DRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSI--GEFAVDKGTEVIINLWALHHNE 403
Query: 323 KYHKNPNVFNPDNFL-PENTQN-RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
K P+ F P+ FL P TQ SY+PF AGPRSC+G A + +L+ +
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
Query: 381 KTTSEISEDQFVLQADIILK---RYDGFKIRIEPR 412
E+ +D + + I K D FK++I+ R
Sbjct: 464 DL--EVPDDGQLPSLEGIPKVVFLIDSFKVKIKVR 496
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 85.0 bits (201), Expect = 4e-16
Identities = 65/215 (30%), Positives = 104/215 (48%), Gaps = 11/215 (5%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+SD+ I + I G +TT + + L L + +++ K+Y+E+ + G S R T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFS-RTPTIS 345
Query: 264 DTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDP 322
D ++ LE I E LRL P P I K D I + + G+ V+I + +H +
Sbjct: 346 DRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSI--GEFAVDKGTEVIINLWALHHNE 403
Query: 323 KYHKNPNVFNPDNFL-PENTQN-RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
K P+ F P+ FL P TQ SY+PF AGPRSC+G A + +L+ +
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
Query: 381 KTTSEISEDQFVLQADIILK---RYDGFKIRIEPR 412
E+ +D + + I K D FK++I+ R
Sbjct: 464 DL--EVPDDGQLPSLEGIPKVVFLIDSFKVKIKVR 496
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 85.0 bits (201), Expect = 4e-16
Identities = 65/215 (30%), Positives = 104/215 (48%), Gaps = 11/215 (5%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+SD+ I + I G +TT + + L L + +++ K+Y+E+ + G S R T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFS-RTPTIS 345
Query: 264 DTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDP 322
D ++ LE I E LRL P P I K D I + + G+ V+I + +H +
Sbjct: 346 DRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSI--GEFAVDKGTEVIINLWALHHNE 403
Query: 323 KYHKNPNVFNPDNFL-PENTQN-RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
K P+ F P+ FL P TQ SY+PF AGPRSC+G A + +L+ +
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
Query: 381 KTTSEISEDQFVLQADIILK---RYDGFKIRIEPR 412
E+ +D + + I K D FK++I+ R
Sbjct: 464 DL--EVPDDGQLPSLEGIPKVVFLIDSFKVKIKVR 496
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 85.0 bits (201), Expect = 4e-16
Identities = 65/215 (30%), Positives = 104/215 (48%), Gaps = 11/215 (5%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+SD+ I + I G +TT + + L L + +++ K+Y+E+ + G S R T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFS-RTPTIS 345
Query: 264 DTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDP 322
D ++ LE I E LRL P P I K D I + + G+ V+I + +H +
Sbjct: 346 DRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSI--GEFAVDKGTEVIINLWALHHNE 403
Query: 323 KYHKNPNVFNPDNFL-PENTQN-RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
K P+ F P+ FL P TQ SY+PF AGPRSC+G A + +L+ +
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
Query: 381 KTTSEISEDQFVLQADIILK---RYDGFKIRIEPR 412
E+ +D + + I K D FK++I+ R
Sbjct: 464 DL--EVPDDGQLPSLEGIPKVVFLIDSFKVKIKVR 496
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 85.0 bits (201), Expect = 4e-16
Identities = 65/215 (30%), Positives = 104/215 (48%), Gaps = 11/215 (5%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+SD+ I + I G +TT + + L L + +++ K+Y+E+ + G S R T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFS-RTPTIS 345
Query: 264 DTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDP 322
D ++ LE I E LRL P P I K D I + + G+ V+I + +H +
Sbjct: 346 DRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSI--GEFAVDKGTEVIINLWALHHNE 403
Query: 323 KYHKNPNVFNPDNFL-PENTQN-RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
K P+ F P+ FL P TQ SY+PF AGPRSC+G A + +L+ +
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
Query: 381 KTTSEISEDQFVLQADIILK---RYDGFKIRIEPR 412
E+ +D + + I K D FK++I+ R
Sbjct: 464 DL--EVPDDGQLPSLEGIPKVVFLIDSFKVKIKVR 496
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 85.0 bits (201), Expect = 4e-16
Identities = 65/215 (30%), Positives = 104/215 (48%), Gaps = 11/215 (5%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+SD+ I + I G +TT + + L L + +++ K+Y+E+ + G S R T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFS-RTPTIS 345
Query: 264 DTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDP 322
D ++ LE I E LRL P P I K D I + + G+ V+I + +H +
Sbjct: 346 DRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSI--GEFAVDKGTEVIINLWALHHNE 403
Query: 323 KYHKNPNVFNPDNFL-PENTQN-RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
K P+ F P+ FL P TQ SY+PF AGPRSC+G A + +L+ +
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
Query: 381 KTTSEISEDQFVLQADIILK---RYDGFKIRIEPR 412
E+ +D + + I K D FK++I+ R
Sbjct: 464 DL--EVPDDGQLPSLEGIPKVVFLIDSFKVKIKVR 496
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 85.0 bits (201), Expect = 4e-16
Identities = 65/215 (30%), Positives = 104/215 (48%), Gaps = 11/215 (5%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+SD+ I + I G +TT + + L L + +++ K+Y+E+ + G S R T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFS-RTPTIS 345
Query: 264 DTLQMKYLERVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDP 322
D ++ LE I E LRL P P I K D I + + G+ V+I + +H +
Sbjct: 346 DRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSI--GEFAVDKGTEVIINLWALHHNE 403
Query: 323 KYHKNPNVFNPDNFL-PENTQN-RHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
K P+ F P+ FL P TQ SY+PF AGPRSC+G A + +L+ +
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
Query: 381 KTTSEISEDQFVLQADIILK---RYDGFKIRIEPR 412
E+ +D + + I K D FK++I+ R
Sbjct: 464 DL--EVPDDGQLPSLEGIPKVVFLIDSFKVKIKVR 496
>L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 217
Score = 84.6 bits (200), Expect = 6e-16
Identities = 53/168 (31%), Positives = 83/168 (49%), Gaps = 4/168 (2%)
Query: 220 GHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESL 279
G +TT+ + L LL H E+ +KV +E+ + G +R D M Y + V+ E
Sbjct: 25 GTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRGHMPYTDAVVHEVQ 83
Query: 280 RLYPPVP-AIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLP 338
R +P ++ +T DV+ NY+IP G+T++ + D K NP +F+P +FL
Sbjct: 84 RYIDLIPTSLPHAVTCDVKF--RNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLD 141
Query: 339 ENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
E + ++PFSAG R CVG A + IL+N+ S I
Sbjct: 142 EGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLI 189
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 84.6 bits (200), Expect = 6e-16
Identities = 60/211 (28%), Positives = 95/211 (45%), Gaps = 4/211 (1%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
AFL M + QN ++ + V ++F G T + + L LL + +Q V +
Sbjct: 271 AFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVRE 330
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
EL G + + + D ++ Y + V+ E+ RL VP I R L R + Y +P
Sbjct: 331 ELNRELG-AGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRF--RGYTLP 387
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V I DP K+P FNPD FL + + R + +++PFS G R C+G A
Sbjct: 388 QGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAK 447
Query: 367 XXXXXXXSTILRNYKTTSEISEDQFVLQADI 397
+TIL+ + S D L+ +
Sbjct: 448 AELFLFFTTILQAFSLESPCPPDTLSLKPTV 478
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 84.2 bits (199), Expect = 8e-16
Identities = 54/198 (27%), Positives = 93/198 (46%), Gaps = 4/198 (2%)
Query: 188 AFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYD 247
+FL M E +N + + F G +T + + LL H E+++KV++
Sbjct: 270 SFLIRMQEEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHE 329
Query: 248 ELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-AIARKLTRDVQIVTNNYIIP 306
E+ + G +R F D +M Y E VI E R +P +A ++ +D + ++ +P
Sbjct: 330 EIDRVIG-KNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKF--RDFFLP 386
Query: 307 AGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAX 366
G+ V RDP++ NP +P +FL E Q + +++PFS G R C G A
Sbjct: 387 KGTEVFPMLGSELRDPRFFSNPQDCSPQHFLDEKGQFKKSDAFVPFSIGKRYCFGEGLAR 446
Query: 367 XXXXXXXSTILRNYKTTS 384
+TI++N++ S
Sbjct: 447 MELFLFFTTIMQNFRFKS 464
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 83.8 bits (198), Expect = 1e-15
Identities = 66/247 (26%), Positives = 109/247 (44%), Gaps = 10/247 (4%)
Query: 169 YRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGS 228
+R+ LD + +D+ + +L M E N S + ++ F G +TT+
Sbjct: 252 HRETLDPSAPKDLID----TYLLHMEEEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTL 307
Query: 229 SFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-A 287
+ L+ + + +VY E+ ++ G R D +M Y E VI E R +P
Sbjct: 308 RYGFLLMLKYPHVAERVYREIEQVIGPH-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMG 366
Query: 288 IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYY 347
+ +T+ YIIP + V + DP Y + P+ FNPD+FL N +
Sbjct: 367 VPHIVTQHTSF--RGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTE 424
Query: 348 SYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVL--QADIILKRYDGF 405
++IPFS G R C+G A +TIL+N+ S ++ + L Q + K +
Sbjct: 425 AFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTY 484
Query: 406 KIRIEPR 412
+IR PR
Sbjct: 485 QIRFLPR 491
>BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein
protein.
Length = 310
Score = 82.6 bits (195), Expect = 2e-15
Identities = 57/219 (26%), Positives = 100/219 (45%), Gaps = 5/219 (2%)
Query: 169 YRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGS 228
Y+D N + E R+ I+ N + + V + G +TT+
Sbjct: 68 YKDQRFLNLMEKFNENLRI-LSSPWIQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTL 126
Query: 229 SFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPA- 287
+ L LL + E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 127 RYGLLLLLKYPEVTAKVQEEIECVVG-RNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTN 185
Query: 288 IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYY 347
+ +T DV+ NY+IP G+T++ + + K NP +F+P +FL ++ +
Sbjct: 186 LPHAVTCDVKF--KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSD 243
Query: 348 SYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
++PFSAG R C+G A +TIL+N+ S++
Sbjct: 244 YFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 282
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 82.6 bits (195), Expect = 2e-15
Identities = 57/219 (26%), Positives = 100/219 (45%), Gaps = 5/219 (2%)
Query: 169 YRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGS 228
Y+D N + E R+ I+ N + + V + G +TT+
Sbjct: 189 YKDQRFLNLMEKFNENLRI-LSSPWIQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTL 247
Query: 229 SFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPA- 287
+ L LL + E+ +KV +E+ + G +R D M Y + V+ E R +P
Sbjct: 248 RYGLLLLLKYPEVTAKVQEEIECVVG-RNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTN 306
Query: 288 IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYY 347
+ +T DV+ NY+IP G+T++ + + K NP +F+P +FL ++ +
Sbjct: 307 LPHAVTCDVKF--KNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSD 364
Query: 348 SYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEI 386
++PFSAG R C+G A +TIL+N+ S++
Sbjct: 365 YFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 403
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 82.2 bits (194), Expect = 3e-15
Identities = 65/247 (26%), Positives = 109/247 (44%), Gaps = 10/247 (4%)
Query: 169 YRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGS 228
+R+ LD + +D+ + +L M + N S + ++ F G +TT+
Sbjct: 252 HRETLDPSAPKDLID----TYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTL 307
Query: 229 SFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-A 287
+ L+ + + +VY E+ ++ G R D +M Y E VI E R +P
Sbjct: 308 RYGFLLMLKYPHVAERVYREIEQVIGPH-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMG 366
Query: 288 IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYY 347
+ +T+ YIIP + V + DP Y + P+ FNPD+FL N +
Sbjct: 367 VPHIVTQHTSF--RGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTE 424
Query: 348 SYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVL--QADIILKRYDGF 405
++IPFS G R C+G A +TIL+N+ S ++ + L Q + K +
Sbjct: 425 AFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTY 484
Query: 406 KIRIEPR 412
+IR PR
Sbjct: 485 QIRFLPR 491
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 82.2 bits (194), Expect = 3e-15
Identities = 65/247 (26%), Positives = 109/247 (44%), Gaps = 10/247 (4%)
Query: 169 YRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGS 228
+R+ LD + +D+ + +L M + N S + ++ F G +TT+
Sbjct: 252 HRETLDPSAPKDLID----TYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTL 307
Query: 229 SFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-A 287
+ L+ + + +VY E+ ++ G R D +M Y E VI E R +P
Sbjct: 308 RYGFLLMLKYPHVAERVYREIEQVIGPH-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMG 366
Query: 288 IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYY 347
+ +T+ YIIP + V + DP Y + P+ FNPD+FL N +
Sbjct: 367 VPHIVTQHTSF--RGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTE 424
Query: 348 SYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVL--QADIILKRYDGF 405
++IPFS G R C+G A +TIL+N+ S ++ + L Q + K +
Sbjct: 425 AFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTY 484
Query: 406 KIRIEPR 412
+IR PR
Sbjct: 485 QIRFLPR 491
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 82.2 bits (194), Expect = 3e-15
Identities = 65/247 (26%), Positives = 109/247 (44%), Gaps = 10/247 (4%)
Query: 169 YRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGS 228
+R+ LD + +D+ + +L M + N S + ++ F G +TT+
Sbjct: 252 HRETLDPSAPRDLID----TYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTL 307
Query: 229 SFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-A 287
+ L+ + + +VY E+ ++ G R D +M Y E VI E R +P
Sbjct: 308 RYGFLLMLKYPHVAERVYREIEQVIGPH-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMG 366
Query: 288 IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYY 347
+ +T+ YIIP + V + DP Y + P+ FNPD+FL N +
Sbjct: 367 VPHIVTQHTSF--RGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTE 424
Query: 348 SYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVL--QADIILKRYDGF 405
++IPFS G R C+G A +TIL+N+ S ++ + L Q + K +
Sbjct: 425 AFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTY 484
Query: 406 KIRIEPR 412
+IR PR
Sbjct: 485 QIRFLPR 491
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 82.2 bits (194), Expect = 3e-15
Identities = 65/247 (26%), Positives = 109/247 (44%), Gaps = 10/247 (4%)
Query: 169 YRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGS 228
+R+ LD + +D+ + +L M + N S + ++ F G +TT+
Sbjct: 252 HRETLDPSAPRDLID----TYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTL 307
Query: 229 SFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-A 287
+ L+ + + +VY E+ ++ G R D +M Y E VI E R +P
Sbjct: 308 RYGFLLMLKYPHVAERVYREIEQVIGPH-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMG 366
Query: 288 IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYY 347
+ +T+ YIIP + V + DP Y + P+ FNPD+FL N +
Sbjct: 367 VPHIVTQHTSF--RGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTE 424
Query: 348 SYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVL--QADIILKRYDGF 405
++IPFS G R C+G A +TIL+N+ S ++ + L Q + K +
Sbjct: 425 AFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTY 484
Query: 406 KIRIEPR 412
+IR PR
Sbjct: 485 QIRFLPR 491
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 82.2 bits (194), Expect = 3e-15
Identities = 65/247 (26%), Positives = 109/247 (44%), Gaps = 10/247 (4%)
Query: 169 YRDDLDFNDEQDVGEKKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGS 228
+R+ LD + +D+ + +L M + N S + ++ F G +TT+
Sbjct: 252 HRETLDPSAPKDLID----TYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTL 307
Query: 229 SFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVP-A 287
+ L+ + + +VY E+ ++ G R D +M Y E VI E R +P
Sbjct: 308 RYGFLLMLKYPHVAERVYREIEQVIGPH-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMG 366
Query: 288 IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYY 347
+ +T+ YIIP + V + DP Y + P+ FNPD+FL N +
Sbjct: 367 VPHIVTQHTSF--RGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTE 424
Query: 348 SYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTSEISEDQFVL--QADIILKRYDGF 405
++IPFS G R C+G A +TIL+N+ S ++ + L Q + K +
Sbjct: 425 AFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTY 484
Query: 406 KIRIEPR 412
+IR PR
Sbjct: 485 QIRFLPR 491
>BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family
51, subfamily A, polypeptide 1 protein.
Length = 509
Score = 81.8 bits (193), Expect = 4e-15
Identities = 52/192 (27%), Positives = 90/192 (46%), Gaps = 2/192 (1%)
Query: 190 LDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDEL 249
L ++++ ++D E+ + ++ G T++ S+++ L + +Q K Y E
Sbjct: 288 LQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQ 347
Query: 250 FEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGS 309
+ G++ +T+ + L+R I E+LRL PPV I ++ R Q V Y IP G
Sbjct: 348 KTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPV-MIMMRMARTPQTVAG-YTIPPGH 405
Query: 310 TVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXX 369
V + R FNPD +L +N + ++Y+PF AG C+G +A
Sbjct: 406 QVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQI 465
Query: 370 XXXXSTILRNYK 381
ST+LR Y+
Sbjct: 466 KTIWSTMLRLYE 477
>U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha
demethylase protein.
Length = 503
Score = 81.4 bits (192), Expect = 5e-15
Identities = 51/192 (26%), Positives = 90/192 (46%), Gaps = 2/192 (1%)
Query: 190 LDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDEL 249
L ++++ ++D E+ + ++ G T++ S+++ L + +Q K Y E
Sbjct: 282 LQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQ 341
Query: 250 FEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGS 309
+ G++ +T+ + L+R I E+LRL PP+ I ++ R Q V Y IP G
Sbjct: 342 KTVCGENLPPLTYDQLKDLNLLDRCIRETLRLRPPI-MIMMRMARTPQTVAG-YTIPPGH 399
Query: 310 TVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXX 369
V + R FNPD +L +N + ++Y+PF AG C+G +A
Sbjct: 400 QVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQI 459
Query: 370 XXXXSTILRNYK 381
ST+LR Y+
Sbjct: 460 KTIWSTMLRLYE 471
>U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase
cytochrome P450 protein.
Length = 509
Score = 81.4 bits (192), Expect = 5e-15
Identities = 51/192 (26%), Positives = 90/192 (46%), Gaps = 2/192 (1%)
Query: 190 LDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDEL 249
L ++++ ++D E+ + ++ G T++ S+++ L + +Q K Y E
Sbjct: 288 LQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQ 347
Query: 250 FEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGS 309
+ G++ +T+ + L+R I E+LRL PP+ I ++ R Q V Y IP G
Sbjct: 348 KTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPI-MIMMRMARTPQTVAG-YTIPPGH 405
Query: 310 TVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXX 369
V + R FNPD +L +N + ++Y+PF AG C+G +A
Sbjct: 406 QVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQI 465
Query: 370 XXXXSTILRNYK 381
ST+LR Y+
Sbjct: 466 KTIWSTMLRLYE 477
>D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase
protein.
Length = 509
Score = 81.4 bits (192), Expect = 5e-15
Identities = 51/192 (26%), Positives = 90/192 (46%), Gaps = 2/192 (1%)
Query: 190 LDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDEL 249
L ++++ ++D E+ + ++ G T++ S+++ L + +Q K Y E
Sbjct: 288 LQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQ 347
Query: 250 FEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGS 309
+ G++ +T+ + L+R I E+LRL PP+ I ++ R Q V Y IP G
Sbjct: 348 KTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPI-MIMMRMARTPQTVAG-YTIPPGH 405
Query: 310 TVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXX 369
V + R FNPD +L +N + ++Y+PF AG C+G +A
Sbjct: 406 QVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQI 465
Query: 370 XXXXSTILRNYK 381
ST+LR Y+
Sbjct: 466 KTIWSTMLRLYE 477
>AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein.
Length = 509
Score = 81.4 bits (192), Expect = 5e-15
Identities = 51/192 (26%), Positives = 90/192 (46%), Gaps = 2/192 (1%)
Query: 190 LDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDEL 249
L ++++ ++D E+ + ++ G T++ S+++ L + +Q K Y E
Sbjct: 288 LQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQ 347
Query: 250 FEIFGDSDRLVTFADTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGS 309
+ G++ +T+ + L+R I E+LRL PP+ I ++ R Q V Y IP G
Sbjct: 348 KTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPI-MIMMRMARTPQTVAG-YTIPPGH 405
Query: 310 TVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXX 369
V + R FNPD +L +N + ++Y+PF AG C+G +A
Sbjct: 406 QVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQI 465
Query: 370 XXXXSTILRNYK 381
ST+LR Y+
Sbjct: 466 KTIWSTMLRLYE 477
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 81.0 bits (191), Expect = 7e-15
Identities = 49/200 (24%), Positives = 95/200 (47%), Gaps = 7/200 (3%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+S E + ++ G DTT+ ++ L L EIQ +++E+ + + ++
Sbjct: 320 LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVV-PAGQVPQHK 378
Query: 264 DTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPK 323
D M L+ V+ E+LRLYP VP +R + +++++ + ++ P + V +++ RDP
Sbjct: 379 DFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV--DGFLFPKNTQFVFCHYEVSRDPT 436
Query: 324 YHKNPNVFNPDNFL----PENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRN 379
P F P +L P + +H + +PF G R+C+GR+ A + +++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496
Query: 380 YKTTSEISEDQFVLQADIIL 399
YK + A I+L
Sbjct: 497 YKVVLAPETGELKSVARIVL 516
>BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family
26, subfamily B, polypeptide 1 protein.
Length = 512
Score = 80.6 bits (190), Expect = 1e-14
Identities = 55/189 (29%), Positives = 96/189 (50%), Gaps = 9/189 (4%)
Query: 184 KKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQS 243
K L LDL+IES++ H ++ E+K+ ++F + TTA+ S+ ++ L H +
Sbjct: 261 KDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320
Query: 244 KVYDEL-----FEIFGDSDRLVTFADTLQ-MKYLERVILESLRLYPPVPAIARKLTRDVQ 297
K+ DEL G DTL ++YL+ VI E +RL+ P+ R + + +
Sbjct: 321 KLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFE 380
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH-YYSYIPFSAGP 356
+ + + IP G +V+ H K+ NVF+PD F ++++ + Y+PF G
Sbjct: 381 L--DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGV 438
Query: 357 RSCVGRKYA 365
R+C+G+ A
Sbjct: 439 RTCLGKHLA 447
>BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family
26, subfamily B, polypeptide 1 protein.
Length = 512
Score = 80.6 bits (190), Expect = 1e-14
Identities = 55/189 (29%), Positives = 96/189 (50%), Gaps = 9/189 (4%)
Query: 184 KKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQS 243
K L LDL+IES++ H ++ E+K+ ++F + TTA+ S+ ++ L H +
Sbjct: 261 KDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320
Query: 244 KVYDEL-----FEIFGDSDRLVTFADTLQ-MKYLERVILESLRLYPPVPAIARKLTRDVQ 297
K+ DEL G DTL ++YL+ VI E +RL+ P+ R + + +
Sbjct: 321 KLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFE 380
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH-YYSYIPFSAGP 356
+ + + IP G +V+ H K+ NVF+PD F ++++ + Y+PF G
Sbjct: 381 L--DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGV 438
Query: 357 RSCVGRKYA 365
R+C+G+ A
Sbjct: 439 RTCLGKHLA 447
>AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoid
metabolizing protein P450RAI-2 protein.
Length = 512
Score = 80.6 bits (190), Expect = 1e-14
Identities = 55/189 (29%), Positives = 96/189 (50%), Gaps = 9/189 (4%)
Query: 184 KKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQS 243
K L LDL+IES++ H ++ E+K+ ++F + TTA+ S+ ++ L H +
Sbjct: 261 KDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320
Query: 244 KVYDEL-----FEIFGDSDRLVTFADTLQ-MKYLERVILESLRLYPPVPAIARKLTRDVQ 297
K+ DEL G DTL ++YL+ VI E +RL+ P+ R + + +
Sbjct: 321 KLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFE 380
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH-YYSYIPFSAGP 356
+ + + IP G +V+ H K+ NVF+PD F ++++ + Y+PF G
Sbjct: 381 L--DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGV 438
Query: 357 RSCVGRKYA 365
R+C+G+ A
Sbjct: 439 RTCLGKHLA 447
>AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein.
Length = 512
Score = 80.6 bits (190), Expect = 1e-14
Identities = 55/189 (29%), Positives = 96/189 (50%), Gaps = 9/189 (4%)
Query: 184 KKRLAFLDLMIESAQNHTCNISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQS 243
K L LDL+IES++ H ++ E+K+ ++F + TTA+ S+ ++ L H +
Sbjct: 261 KDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320
Query: 244 KVYDEL-----FEIFGDSDRLVTFADTLQ-MKYLERVILESLRLYPPVPAIARKLTRDVQ 297
K+ DEL G DTL ++YL+ VI E +RL+ P+ R + + +
Sbjct: 321 KLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFE 380
Query: 298 IVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVFNPDNFLPENTQNRH-YYSYIPFSAGP 356
+ + + IP G +V+ H K+ NVF+PD F ++++ + Y+PF G
Sbjct: 381 L--DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGV 438
Query: 357 RSCVGRKYA 365
R+C+G+ A
Sbjct: 439 RTCLGKHLA 447
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/200 (24%), Positives = 94/200 (47%), Gaps = 7/200 (3%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+S E + ++ G DTT+ ++ L L EIQ +++E+ + + ++
Sbjct: 319 LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQHK 377
Query: 264 DTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPK 323
D M L+ V+ E+LRLYP VP +R + +++++ + ++ P + V + + RDP
Sbjct: 378 DFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV--DGFLFPKNTQFVFCHYVVSRDPT 435
Query: 324 YHKNPNVFNPDNFL----PENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRN 379
P F P +L P + +H + +PF G R+C+GR+ A + +++
Sbjct: 436 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 495
Query: 380 YKTTSEISEDQFVLQADIIL 399
YK + A I+L
Sbjct: 496 YKVVLAPETGELKSVARIVL 515
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/200 (24%), Positives = 94/200 (47%), Gaps = 7/200 (3%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+S E + ++ G DTT+ ++ L L EIQ +++E+ + + ++
Sbjct: 320 LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQHK 378
Query: 264 DTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPK 323
D M L+ V+ E+LRLYP VP +R + +++++ + ++ P + V + + RDP
Sbjct: 379 DFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV--DGFLFPKNTQFVFCHYVVSRDPT 436
Query: 324 YHKNPNVFNPDNFL----PENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRN 379
P F P +L P + +H + +PF G R+C+GR+ A + +++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496
Query: 380 YKTTSEISEDQFVLQADIIL 399
YK + A I+L
Sbjct: 497 YKVVLAPETGELKSVARIVL 516
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/169 (28%), Positives = 84/169 (49%), Gaps = 4/169 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLE 272
V + F G +TT+ + L +L + EI+ K+++E+ + G S R+ D +M Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPS-RIPAIKDRQEMPYMD 351
Query: 273 RVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
V+ E R VP+ + + TRD + Y+IP G+ VV + D + +P F
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDT--IFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKF 409
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
P++FL EN + ++ + PFS G R C G A IL+++
Sbjct: 410 KPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARTELFLLLCAILQHF 458
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/169 (28%), Positives = 84/169 (49%), Gaps = 4/169 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLE 272
V + F G +TT+ + L +L + EI+ K+++E+ + G S R+ D +M Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPS-RIPAIKDRQEMPYMD 351
Query: 273 RVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
V+ E R VP+ + + TRD + Y+IP G+ VV + D + +P F
Sbjct: 352 AVVREIQRFITLVPSNLPHEATRDT--IFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKF 409
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
P++FL EN + ++ + PFS G R C G A IL+++
Sbjct: 410 KPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHF 458
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/200 (24%), Positives = 94/200 (47%), Gaps = 7/200 (3%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+S E + ++ G DTT+ ++ L L EIQ +++E+ + + ++
Sbjct: 320 LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQHK 378
Query: 264 DTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPK 323
D M L+ V+ E+LRLYP VP +R + +++++ + ++ P + V + + RDP
Sbjct: 379 DFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV--DGFLFPKNTQFVFCHYVVSRDPT 436
Query: 324 YHKNPNVFNPDNFL----PENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRN 379
P F P +L P + +H + +PF G R+C+GR+ A + +++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496
Query: 380 YKTTSEISEDQFVLQADIIL 399
YK + A I+L
Sbjct: 497 YKVVLAPETGELKSVARIVL 516
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 79.8 bits (188), Expect = 2e-14
Identities = 49/200 (24%), Positives = 94/200 (47%), Gaps = 7/200 (3%)
Query: 204 ISDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFA 263
+S E + ++ G DTT+ ++ L L EIQ +++E+ + + ++
Sbjct: 320 LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQHK 378
Query: 264 DTLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPK 323
D M L+ V+ E+LRLYP VP +R + +++++ + ++ P + V + + RDP
Sbjct: 379 DFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV--DGFLFPKNTQFVFCHYVVSRDPT 436
Query: 324 YHKNPNVFNPDNFL----PENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRN 379
P F P +L P + +H + +PF G R+C+GR+ A + +++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496
Query: 380 YKTTSEISEDQFVLQADIIL 399
YK + A I+L
Sbjct: 497 YKVVLAPETGELKSVARIVL 516
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 79.4 bits (187), Expect = 2e-14
Identities = 49/169 (28%), Positives = 84/169 (49%), Gaps = 4/169 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLE 272
V + F G +TT+ + L +L + EI+ K+++E+ + G S R+ D +M Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPS-RIPAIKDRQEMPYMD 351
Query: 273 RVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
V+ E R VP+ + + TRD + Y+IP G+ VV + D + +P F
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDT--IFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKF 409
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
P++FL EN + ++ + PFS G R C G A IL+++
Sbjct: 410 KPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHF 458
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 79.4 bits (187), Expect = 2e-14
Identities = 49/169 (28%), Positives = 84/169 (49%), Gaps = 4/169 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLE 272
V + F G +TT+ + L +L + EI+ K+++E+ + G S R+ D +M Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPS-RIPAIKDRQEMPYMD 351
Query: 273 RVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
V+ E R VP+ + + TRD + Y+IP G+ VV + D + +P F
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDT--IFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKF 409
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
P++FL EN + ++ + PFS G R C G A IL+++
Sbjct: 410 KPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHF 458
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 79.4 bits (187), Expect = 2e-14
Identities = 49/169 (28%), Positives = 84/169 (49%), Gaps = 4/169 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLE 272
V + F G +TT+ + L +L + EI+ K+++E+ + G S R+ D +M Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPS-RIPAIKDRQEMPYMD 351
Query: 273 RVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
V+ E R VP+ + + TRD + Y+IP G+ VV + D + +P F
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDT--IFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKF 409
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
P++FL EN + ++ + PFS G R C G A IL+++
Sbjct: 410 KPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHF 458
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 79.4 bits (187), Expect = 2e-14
Identities = 49/169 (28%), Positives = 84/169 (49%), Gaps = 4/169 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLE 272
V + F G +TT+ + L +L + EI+ K+++E+ + G S R+ D +M Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPS-RIPAIKDRQEMPYMD 351
Query: 273 RVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
V+ E R VP+ + + TRD + Y+IP G+ VV + D + +P F
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDT--IFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKF 409
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
P++FL EN + ++ + PFS G R C G A IL+++
Sbjct: 410 KPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHF 458
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 79.4 bits (187), Expect = 2e-14
Identities = 49/169 (28%), Positives = 84/169 (49%), Gaps = 4/169 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLE 272
V + F G +TT+ + L +L + EI+ K+++E+ + G S R+ D +M Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPS-RIPAIKDRQEMPYMD 351
Query: 273 RVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
V+ E R VP+ + + TRD + Y+IP G+ VV + D + +P F
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDT--IFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKF 409
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
P++FL EN + ++ + PFS G R C G A IL+++
Sbjct: 410 KPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHF 458
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 79.4 bits (187), Expect = 2e-14
Identities = 49/169 (28%), Positives = 84/169 (49%), Gaps = 4/169 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLE 272
V + F G +TT+ + L +L + EI+ K+++E+ + G S R+ D +M Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPS-RIPAIKDRQEMPYMD 351
Query: 273 RVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
V+ E R VP+ + + TRD + Y+IP G+ VV + D + +P F
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDT--IFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKF 409
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
P++FL EN + ++ + PFS G R C G A IL+++
Sbjct: 410 KPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHF 458
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 79.4 bits (187), Expect = 2e-14
Identities = 49/169 (28%), Positives = 84/169 (49%), Gaps = 4/169 (2%)
Query: 213 VDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQMKYLE 272
V + F G +TT+ + L +L + EI+ K+++E+ + G S R+ D +M Y++
Sbjct: 262 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPS-RIPAIKDRQEMPYMD 320
Query: 273 RVILESLRLYPPVPA-IARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKNPNVF 331
V+ E R VP+ + + TRD + Y+IP G+ VV + D + +P F
Sbjct: 321 AVVHEIQRFITLVPSNLPHEATRDT--IFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKF 378
Query: 332 NPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY 380
P++FL EN + ++ + PFS G R C G A IL+++
Sbjct: 379 KPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHF 427
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 78.6 bits (185), Expect = 4e-14
Identities = 51/181 (28%), Positives = 89/181 (49%), Gaps = 6/181 (3%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI V ++ G DTT+ S+ + LL H E+Q VY E+ + G+ + T AD +
Sbjct: 169 EIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGER-HVPTAADVPK 227
Query: 268 MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKN 327
+ + ++ E+LRL+P +P R D +V Y+IP G+ + + + +
Sbjct: 228 VPLVRALLKETLRLFPVLPGNGRVTQED--LVIGGYLIPKGTQLALCHYATSYQDENFPR 285
Query: 328 PNVFNPDNFLPENTQNR-HYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY--KTTS 384
F P+ +L + +R + IPF G RSC+GR+ A +L+++ KT+S
Sbjct: 286 AKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSS 345
Query: 385 E 385
+
Sbjct: 346 Q 346
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 77.8 bits (183), Expect = 7e-14
Identities = 62/255 (24%), Positives = 117/255 (45%), Gaps = 15/255 (5%)
Query: 147 KDTNDSIMEDSAKTLS-DTVFKGYRDDLDFNDEQDVGEKKRLAFL-DLMIESAQNHTCNI 204
K N + +D TL+ DT+FK + +D N + ++ FL D+ H +
Sbjct: 4 KSLNTKVWQDH--TLAWDTIFKSVKACID-NRLEKYSQQPSADFLCDIY------HQNRL 54
Query: 205 SDHEIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFAD 264
S E+ V + +TTA ++L L + ++Q K+ E+ + ++ ++ D
Sbjct: 55 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPEN-QVPRAED 113
Query: 265 TLQMKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKY 324
M YL+ + ES+RL P VP R L D V Y +P G+ +++ T +
Sbjct: 114 LRNMPYLKACLKESMRLTPSVPFTTRTL--DKATVLGEYALPKGTVLMLNTQVLGSSEDN 171
Query: 325 HKNPNVFNPDNFLPENTQNRHYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNYKTTS 384
++ + F P+ +L E + + ++++PF G R C+GR+ A I+R Y +
Sbjct: 172 FEDSSQFRPERWLQEK-EKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQA 230
Query: 385 EISEDQFVLQADIIL 399
+E +L + ++
Sbjct: 231 TDNEPVEMLHSGTLV 245
>BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein.
Length = 372
Score = 77.8 bits (183), Expect = 7e-14
Identities = 50/181 (27%), Positives = 89/181 (49%), Gaps = 6/181 (3%)
Query: 208 EIKEEVDTIMFEGHDTTAAGSSFVLCLLGIHQEIQSKVYDELFEIFGDSDRLVTFADTLQ 267
EI V ++ G DTT+ S+ + +L H E+Q VY E+ + G+ + T AD +
Sbjct: 169 EIYANVTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGER-HVPTAADVPK 227
Query: 268 MKYLERVILESLRLYPPVPAIARKLTRDVQIVTNNYIIPAGSTVVIGTFKIHRDPKYHKN 327
+ + ++ E+LRL+P +P R D +V Y+IP G+ + + + +
Sbjct: 228 VPLVRALLKETLRLFPVLPGNGRVTQED--LVIGGYLIPKGTQLALCHYATSYQDENFPR 285
Query: 328 PNVFNPDNFLPENTQNR-HYYSYIPFSAGPRSCVGRKYAXXXXXXXXSTILRNY--KTTS 384
F P+ +L + +R + IPF G RSC+GR+ A +L+++ KT+S
Sbjct: 286 AKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSS 345
Query: 385 E 385
+
Sbjct: 346 Q 346
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.136 0.393
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 56,254,542
Number of Sequences: 224733
Number of extensions: 2229463
Number of successful extensions: 5950
Number of sequences better than 10.0: 475
Number of HSP's better than 10.0 without gapping: 341
Number of HSP's successfully gapped in prelim test: 134
Number of HSP's that attempted gapping in prelim test: 4808
Number of HSP's gapped (non-prelim): 594
length of query: 420
length of database: 73,234,838
effective HSP length: 92
effective length of query: 328
effective length of database: 52,559,402
effective search space: 17239483856
effective search space used: 17239483856
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
- SilkBase 1999-2023 -