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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001000-TA|BGIBMGA001000-PA|IPR001092|Basic
helix-loop-helix dimerisation region bHLH, IPR011598|Helix-loop-helix
DNA-binding
         (187 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_27345| Best HMM Match : HLH (HMM E-Value=1.2e-20)                   62   4e-10
SB_32910| Best HMM Match : No HMM Matches (HMM E-Value=.)              61   5e-10
SB_43185| Best HMM Match : HLH (HMM E-Value=4e-20)                     58   6e-09
SB_535| Best HMM Match : No HMM Matches (HMM E-Value=.)                44   6e-05
SB_37377| Best HMM Match : No HMM Matches (HMM E-Value=.)              44   1e-04
SB_52528| Best HMM Match : HLH (HMM E-Value=3.9e-18)                   39   0.003
SB_12347| Best HMM Match : HLH (HMM E-Value=3.8e-21)                   38   0.004
SB_56922| Best HMM Match : HLH (HMM E-Value=1.9e-21)                   37   0.009
SB_35548| Best HMM Match : BPL_LipA_LipB (HMM E-Value=1.5e-27)         35   0.048
SB_47522| Best HMM Match : HLH (HMM E-Value=1e-17)                     35   0.048
SB_26423| Best HMM Match : No HMM Matches (HMM E-Value=.)              35   0.048
SB_6246| Best HMM Match : No HMM Matches (HMM E-Value=.)               34   0.083
SB_9126| Best HMM Match : HLH (HMM E-Value=2.5e-18)                    32   0.25 
SB_3829| Best HMM Match : HLH (HMM E-Value=4.4e-12)                    30   1.0  
SB_47523| Best HMM Match : HLH (HMM E-Value=1.1e-18)                   30   1.0  
SB_20446| Best HMM Match : HLH (HMM E-Value=1.26117e-44)               30   1.4  
SB_17080| Best HMM Match : No HMM Matches (HMM E-Value=.)              29   3.1  
SB_12345| Best HMM Match : HLH (HMM E-Value=1.4e-12)                   29   3.1  
SB_46206| Best HMM Match : HLH (HMM E-Value=5e-18)                     27   7.2  
SB_41383| Best HMM Match : No HMM Matches (HMM E-Value=.)              27   9.5  

>SB_27345| Best HMM Match : HLH (HMM E-Value=1.2e-20)
          Length = 153

 Score = 61.7 bits (143), Expect = 4e-10
 Identities = 36/87 (41%), Positives = 51/87 (58%), Gaps = 13/87 (14%)

Query: 19  KKYNYKNCSHNGTQAASIARRNARERNRVKQVNDGFNALRKRLPXXXXXXXXXXXXXXXX 78
           +K +  NC  N  +  S+ RRN RERNRVK V+DGF ALRK +P                
Sbjct: 58  RKCSSPNC--NKKEHVSVLRRNERERNRVKLVSDGFAALRKHIP-----------TTPVN 104

Query: 79  XXXSKVDTLRMVVEYIRYLQNMIDESD 105
              SKV+TLR  +EYI++LQ ++++S+
Sbjct: 105 KKLSKVETLRTAIEYIKHLQRILNDSN 131


>SB_32910| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 155

 Score = 61.3 bits (142), Expect = 5e-10
 Identities = 45/110 (40%), Positives = 64/110 (58%), Gaps = 18/110 (16%)

Query: 4   IAPAPE-TRLTLE-LE---PKKYNYKNCSHNG--TQAASIARRNARERNRVKQVNDGFNA 56
           IAPA + T++ LE LE    K    K C+      + +++ARRN RERNRV+ VNDGF++
Sbjct: 33  IAPAKKKTKVALESLEGSNTKVVAKKKCTTLAFHMEPSAVARRNERERNRVRLVNDGFSS 92

Query: 57  LRKRLPXXXXXXXXXXXXXXXXXXXSKVDTLRMVVEYIRYLQNMIDESDA 106
           LR+ +P                   SKV+TLR  V YI++LQ++I+E DA
Sbjct: 93  LRQHIP-----------YFPEKKKLSKVETLRCAVAYIKHLQSLIEEYDA 131


>SB_43185| Best HMM Match : HLH (HMM E-Value=4e-20)
          Length = 232

 Score = 57.6 bits (133), Expect = 6e-09
 Identities = 33/74 (44%), Positives = 44/74 (59%), Gaps = 11/74 (14%)

Query: 32  QAASIARRNARERNRVKQVNDGFNALRKRLPXXXXXXXXXXXXXXXXXXXSKVDTLRMVV 91
           + A +ARRNARER RVK VNDGF  LRK +P                   SKV TLR  +
Sbjct: 62  EPAVVARRNARERKRVKLVNDGFMRLRKHVP-----------TDPKNKKLSKVKTLRSAI 110

Query: 92  EYIRYLQNMIDESD 105
           EYIR+LQ+++ +++
Sbjct: 111 EYIRHLQHLLGQAN 124


>SB_535| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 131

 Score = 44.4 bits (100), Expect = 6e-05
 Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 12/76 (15%)

Query: 32  QAASIARRNARERNRVKQVNDGFNALRKRLPXXXXXXXXXXXXXXXXXXXSKVDTLRMVV 91
           + A I +RN RER RV+ VN+G+  LR+ LP                   SKV+TLR  +
Sbjct: 51  EPAFIRKRNERERIRVRHVNEGYARLREHLP-----------EEPSDKRMSKVETLRAAI 99

Query: 92  EYIRYLQNMIDESDAA 107
            YI++L++++ +++AA
Sbjct: 100 RYIKHLESLL-QAEAA 114


>SB_37377| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 181

 Score = 43.6 bits (98), Expect = 1e-04
 Identities = 35/110 (31%), Positives = 53/110 (48%), Gaps = 16/110 (14%)

Query: 10  TRLTLELEPK-KYNYKNCSHNGTQAASIARRNA---RERNRVKQVNDGFNALRKRLPXXX 65
           T+ T  ++ + + N K      +Q   I +R+A   RER R++ +N+ F  LRK +P   
Sbjct: 15  TQFTYAIQTQDEKNLKRKRRRKSQNQQIVQRHAANLRERKRMQSINEAFEGLRKHIP--- 71

Query: 66  XXXXXXXXXXXXXXXXSKVDTLRMVVEYIRYLQNMIDESDAALGIPKQPS 115
                           SKVDTLR+ + YI +L  MI+ SD +     QPS
Sbjct: 72  --------TLPYEKRLSKVDTLRLAIGYIGFLTEMIN-SDMSHSQALQPS 112


>SB_52528| Best HMM Match : HLH (HMM E-Value=3.9e-18)
          Length = 138

 Score = 38.7 bits (86), Expect = 0.003
 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 13/101 (12%)

Query: 40  NARERNRVKQVNDGFNALRKRLPXXXXXXXXXXXXXXXXXXXSKVDTLRMVVEYIRYLQN 99
           N RERNRV+QVN  F  LR ++P                   SK+DT+R+   YI+ L  
Sbjct: 41  NERERNRVQQVNAAFETLRNKIP-----------LRALEKKPSKIDTIRLATRYIQDLTQ 89

Query: 100 MID--ESDAALGIPKQPSIDLSTISYEADDGVFERSSPYTD 138
           ++   E++  +  P   +  + + +    DG    S+   D
Sbjct: 90  LLSLAETEGRITSPSSSNGSVYSSTIADHDGSLYSSTTDQD 130


>SB_12347| Best HMM Match : HLH (HMM E-Value=3.8e-21)
          Length = 143

 Score = 38.3 bits (85), Expect = 0.004
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 14/84 (16%)

Query: 40  NARERNRVKQVNDGFNALRKRLPXXXXXXXXXXXXXXXXXXXSKVDTLRMVVEYIRYLQN 99
           NARERNR   VN  FNALR  +P                   SK++TLR+   YI +L  
Sbjct: 56  NARERNRTHSVNAAFNALRLLIP-----------TEPSDRKLSKIETLRLASSYIAHLST 104

Query: 100 MIDESDAALGIPKQPSID-LSTIS 122
           ++        +P   S+D + TIS
Sbjct: 105 ILISGTQCPNVPS--SMDHIRTIS 126


>SB_56922| Best HMM Match : HLH (HMM E-Value=1.9e-21)
          Length = 157

 Score = 37.1 bits (82), Expect = 0.009
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 11/65 (16%)

Query: 40  NARERNRVKQVNDGFNALRKRLPXXXXXXXXXXXXXXXXXXXSKVDTLRMVVEYIRYLQN 99
           N +ER R + +N  F  LR  +P                   SK+ TLR+ + YIRYL +
Sbjct: 37  NRKERKRTQTMNTAFEDLRNHIPNVPPDTKL-----------SKIKTLRLAISYIRYLMD 85

Query: 100 MIDES 104
           +++ES
Sbjct: 86  ILEES 90


>SB_35548| Best HMM Match : BPL_LipA_LipB (HMM E-Value=1.5e-27)
          Length = 378

 Score = 34.7 bits (76), Expect = 0.048
 Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 7/68 (10%)

Query: 38  RRNARERNRVKQVNDGFNALRKRLPXXXXXXXXXXXXXXXXXXXSKVDTLRMVVEYIRYL 97
           RRNARER R  ++N  F+ LR  +P                   ++++TLR+   YI  L
Sbjct: 297 RRNARERERQGRLNSAFDVLRGVIP-------DYLSGKGPERKLTQIETLRLATHYIMAL 349

Query: 98  QNMIDESD 105
             M+++ +
Sbjct: 350 SEMLEDEN 357


>SB_47522| Best HMM Match : HLH (HMM E-Value=1e-17)
          Length = 213

 Score = 34.7 bits (76), Expect = 0.048
 Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 9/61 (14%)

Query: 41  ARERNRVKQVNDGFNALRKRLPXXXXXXXXXXXXXXXXXXXSKVDTLRMVVEYIRYLQNM 100
           ARER+R+  +ND F++LRK +P                   SK+ TLR+ + YI  L ++
Sbjct: 74  ARERSRMHSLNDAFDSLRKAIP---------KTNYNQEEKPSKIATLRLAIHYIAALSDI 124

Query: 101 I 101
           +
Sbjct: 125 L 125


>SB_26423| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 175

 Score = 34.7 bits (76), Expect = 0.048
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 10/71 (14%)

Query: 40  NARERNRVKQVNDGFNALRKRLPXXXXXXXXXXXXXXXXXXXSKVDTLRMVVEYIRYLQN 99
           NARERNR++ ++D    LR  LP                   SK+ TLR+ + YI  L  
Sbjct: 43  NARERNRMRSISDALLHLRYHLP---------QTVVAKDKKLSKIQTLRLAIRYISDLFE 93

Query: 100 MIDESDAALGI 110
           ++ +SD   GI
Sbjct: 94  IL-QSDDGQGI 103


>SB_6246| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 135

 Score = 33.9 bits (74), Expect = 0.083
 Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 15/101 (14%)

Query: 8   PETRLTLELEPKK--YNYKNCSHNGTQAASIAR--RNARERNRVKQVNDGFNALRKRLPX 63
           PE++      PK   +  ++  H  T  A + R   N RER R++ +N    ALRK +P 
Sbjct: 31  PESKKQSTFPPKMRLHPEESSKHKITAEARLRRLRANDRERRRIQSINVALEALRKAVP- 89

Query: 64  XXXXXXXXXXXXXXXXXXSKVDTLRMVVEYIRYLQNMIDES 104
                             +K+DTL +  +YI++L  ++  +
Sbjct: 90  ----------NTRSSGKLTKLDTLLLARDYIKHLNEILQRT 120


>SB_9126| Best HMM Match : HLH (HMM E-Value=2.5e-18)
          Length = 179

 Score = 32.3 bits (70), Expect = 0.25
 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 11/88 (12%)

Query: 38  RRNARERNRVKQVNDGFNALRKRLPXXXXXXXXXXXXXXXXXXXSKVDTLRMVVEYIRYL 97
           + +ARER R   +N+    LRK++P                   SK++ LR+ ++YI  L
Sbjct: 42  KASARERKRRHVLNNALELLRKKVPCVDQNPQKL----------SKIEVLRLAIDYIAML 91

Query: 98  QNMIDESDAALGIPKQPSIDLSTISYEA 125
              ++ S +A  +  QP++  S  S  A
Sbjct: 92  SCYLNNSQSA-AVCSQPALSASIGSQAA 118


>SB_3829| Best HMM Match : HLH (HMM E-Value=4.4e-12)
          Length = 1650

 Score = 30.3 bits (65), Expect = 1.0
 Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 9/62 (14%)

Query: 42  RERNRVKQVNDGFNALRKRLPXXXXXXXXXXXXXXXXXXXSKVDTLRMVVEYIRYLQNMI 101
           RE+ R++  N  F+ALR+ L                    +K++TLR+ +EYI+ L   +
Sbjct: 77  REKRRLQMSNKAFDALRESL---------YNFAKTGSRRLTKLETLRLAIEYIKELTQSL 127

Query: 102 DE 103
           +E
Sbjct: 128 NE 129


>SB_47523| Best HMM Match : HLH (HMM E-Value=1.1e-18)
          Length = 207

 Score = 30.3 bits (65), Expect = 1.0
 Identities = 16/47 (34%), Positives = 29/47 (61%), Gaps = 3/47 (6%)

Query: 19 KKYNYKNCSHNGTQAASIARR---NARERNRVKQVNDGFNALRKRLP 62
          K+   K+   N  + ++ +RR   NARER+R+  +++ F +LRK +P
Sbjct: 26 KRKKDKSKKTNSWKHSNRSRRLIANARERSRIHTMSEAFESLRKAVP 72


>SB_20446| Best HMM Match : HLH (HMM E-Value=1.26117e-44)
          Length = 424

 Score = 29.9 bits (64), Expect = 1.4
 Identities = 11/23 (47%), Positives = 16/23 (69%)

Query: 40 NARERNRVKQVNDGFNALRKRLP 62
          N+ ER R++ +N GF ALR  +P
Sbjct: 49 NSNERRRMQSINSGFQALRMLIP 71



 Score = 29.9 bits (64), Expect = 1.4
 Identities = 11/23 (47%), Positives = 16/23 (69%)

Query: 40  NARERNRVKQVNDGFNALRKRLP 62
           N+ ER R++ +N GF ALR  +P
Sbjct: 216 NSNERRRMQSINSGFQALRMLIP 238


>SB_17080| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 313

 Score = 28.7 bits (61), Expect = 3.1
 Identities = 12/32 (37%), Positives = 21/32 (65%)

Query: 31 TQAASIARRNARERNRVKQVNDGFNALRKRLP 62
          T+++     N +ER RV+++N+ F  LR+ LP
Sbjct: 18 TESSKRLEANKKERMRVQKMNNAFQDLRRVLP 49


>SB_12345| Best HMM Match : HLH (HMM E-Value=1.4e-12)
          Length = 124

 Score = 28.7 bits (61), Expect = 3.1
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 4/52 (7%)

Query: 15 ELEPKKYNYKNCSHNGTQAASIARR----NARERNRVKQVNDGFNALRKRLP 62
          E E  +   K     G +   ++++    NARERNRV  +N     LR+ +P
Sbjct: 24 EPESPQQKKKKARRRGPRLTGVSKQRRLANARERNRVHILNTNIQVLRELIP 75


>SB_46206| Best HMM Match : HLH (HMM E-Value=5e-18)
          Length = 400

 Score = 27.5 bits (58), Expect = 7.2
 Identities = 11/25 (44%), Positives = 17/25 (68%)

Query: 38  RRNARERNRVKQVNDGFNALRKRLP 62
           R N RER R+K +N   ++L+K +P
Sbjct: 307 RANDRERRRMKSLNRALDSLKKCIP 331


>SB_41383| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1995

 Score = 27.1 bits (57), Expect = 9.5
 Identities = 14/47 (29%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 6   PAPETRLTLELEPKKYNYKNCSH-NGTQAASIARRNARERNRVKQVN 51
           P+P    T  L+P+    K+ S+ N T+A S  +   +  +  KQ N
Sbjct: 588 PSPPATTTASLKPQNNKQKDSSNKNSTKATSRKKSKVQSISHTKQAN 634


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.314    0.131    0.378 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 5,091,413
Number of Sequences: 59808
Number of extensions: 162006
Number of successful extensions: 271
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 241
Number of HSP's gapped (non-prelim): 29
length of query: 187
length of database: 16,821,457
effective HSP length: 78
effective length of query: 109
effective length of database: 12,156,433
effective search space: 1325051197
effective search space used: 1325051197
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (22.0 bits)
S2: 57 (27.1 bits)

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