Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000994-TA|BGIBMGA000994-PA|IPR010097|Malate
dehydrogenase, NAD-dependent, eukaryotes and gamma proteobacteria,
IPR001236|Lactate/malate dehydrogenase
(329 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR536548-1|CAG38785.1| 338|Homo sapiens MDH2 protein. 186 7e-47
BC001917-1|AAH01917.1| 338|Homo sapiens malate dehydrogenase 2,... 186 7e-47
AF047470-1|AAC03787.1| 338|Homo sapiens malate dehydrogenase pr... 186 7e-47
AC005077-1|AAS07425.1| 316|Homo sapiens unknown protein. 186 7e-47
DQ402957-1|ABD77290.1| 305|Homo sapiens mitochondrial malate de... 181 4e-45
Y00711-1|CAA68701.1| 334|Homo sapiens protein ( Human mRNA for ... 40 0.009
X13794-1|CAA32033.1| 334|Homo sapiens lactate dehydrogenase B p... 40 0.009
BT019765-1|AAV38570.1| 334|Homo sapiens lactate dehydrogenase B... 40 0.009
BT019764-1|AAV38569.1| 334|Homo sapiens lactate dehydrogenase B... 40 0.009
BC071860-1|AAH71860.1| 334|Homo sapiens lactate dehydrogenase B... 40 0.009
BC015122-1|AAH15122.1| 334|Homo sapiens lactate dehydrogenase B... 40 0.009
BC002362-1|AAH02362.1| 334|Homo sapiens lactate dehydrogenase B... 40 0.009
AY189689-1|AAO85222.1| 334|Homo sapiens transformation-related ... 40 0.009
U13680-1|AAA21348.1| 332|Homo sapiens lactate dehydrogenase-C p... 40 0.016
BC090043-1|AAH90043.1| 332|Homo sapiens lactate dehydrogenase C... 40 0.016
BC064388-1|AAH64388.1| 332|Homo sapiens lactate dehydrogenase C... 40 0.016
BC019249-1|AAH19249.3| 332|Homo sapiens lactate dehydrogenase C... 40 0.016
M24515-1|AAA59508.1| 266|Homo sapiens lactate dehydrogenase-C p... 39 0.028
AY286300-1|AAP37402.1| 332|Homo sapiens lactate dehydrogenase C... 39 0.028
J02938-1|AAA59507.1| 332|Homo sapiens LDHC protein. 37 0.11
BC014340-1|AAH14340.1| 234|Homo sapiens LDHAL6A protein protein. 37 0.11
AY581313-1|AAS93432.1| 332|Homo sapiens lactate dehydrogenase p... 37 0.11
AK131523-1|BAD18662.1| 332|Homo sapiens protein ( Homo sapiens ... 37 0.11
BC022034-1|AAH22034.1| 381|Homo sapiens lactate dehydrogenase A... 36 0.20
AY642121-1|AAT65080.1| 381|Homo sapiens lactacte dehydrogenase ... 36 0.20
AY009108-1|AAG49399.1| 381|Homo sapiens lactate dehydrogenase A... 36 0.20
AK058192-1|BAB71710.1| 381|Homo sapiens protein ( Homo sapiens ... 36 0.20
AK127961-1|BAC87208.1| 243|Homo sapiens protein ( Homo sapiens ... 36 0.26
>CR536548-1|CAG38785.1| 338|Homo sapiens MDH2 protein.
Length = 338
Score = 186 bits (454), Expect = 7e-47
Identities = 93/311 (29%), Positives = 167/311 (53%), Gaps = 3/311 (0%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFTPGVTLDLSQIPSPSRILGLTGED 78
+V V+GA+ +GQ +++L ++D TPGV DLS I + + + G G +
Sbjct: 26 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPE 84
Query: 79 TLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPI 138
L LK D+++ G+ ++P ++ L N+ + ++ + + CP + ++ P+
Sbjct: 85 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPV 144
Query: 139 NYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKT 198
N IP+TAE+ + HGVY+ K+FG+T +D +R+ A L VPVIGGH+ KT
Sbjct: 145 NSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKT 204
Query: 199 IVPLLSQAKPTVEMKEKDLEEFTIKLRNCDGMITKAKRGC-IPNLSVAYSSFLFTKSILD 257
I+PL+SQ P V+ + L T +++ + KAK G LS+AY+ F S++D
Sbjct: 205 IIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVD 264
Query: 258 ALEGSPAKIH-AFVDNNDFGTSYFSSLVNLDKNGVKEMVRYSEFSKFECDLIEKSLQQLR 316
A+ G + +FV + + +YFS+ + L K G+++ + + S FE +I ++ +L+
Sbjct: 265 AMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELK 324
Query: 317 KDVSKGRKILE 327
+ KG ++
Sbjct: 325 ASIKKGEDFVK 335
>BC001917-1|AAH01917.1| 338|Homo sapiens malate dehydrogenase 2,
NAD (mitochondrial) protein.
Length = 338
Score = 186 bits (454), Expect = 7e-47
Identities = 93/311 (29%), Positives = 167/311 (53%), Gaps = 3/311 (0%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFTPGVTLDLSQIPSPSRILGLTGED 78
+V V+GA+ +GQ +++L ++D TPGV DLS I + + + G G +
Sbjct: 26 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPE 84
Query: 79 TLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPI 138
L LK D+++ G+ ++P ++ L N+ + ++ + + CP + ++ P+
Sbjct: 85 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPV 144
Query: 139 NYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKT 198
N IP+TAE+ + HGVY+ K+FG+T +D +R+ A L VPVIGGH+ KT
Sbjct: 145 NSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKT 204
Query: 199 IVPLLSQAKPTVEMKEKDLEEFTIKLRNCDGMITKAKRGC-IPNLSVAYSSFLFTKSILD 257
I+PL+SQ P V+ + L T +++ + KAK G LS+AY+ F S++D
Sbjct: 205 IIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVD 264
Query: 258 ALEGSPAKIH-AFVDNNDFGTSYFSSLVNLDKNGVKEMVRYSEFSKFECDLIEKSLQQLR 316
A+ G + +FV + + +YFS+ + L K G+++ + + S FE +I ++ +L+
Sbjct: 265 AMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELK 324
Query: 317 KDVSKGRKILE 327
+ KG ++
Sbjct: 325 ASIKKGEDFVK 335
>AF047470-1|AAC03787.1| 338|Homo sapiens malate dehydrogenase
precursor protein.
Length = 338
Score = 186 bits (454), Expect = 7e-47
Identities = 93/311 (29%), Positives = 167/311 (53%), Gaps = 3/311 (0%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFTPGVTLDLSQIPSPSRILGLTGED 78
+V V+GA+ +GQ +++L ++D TPGV DLS I + + + G G +
Sbjct: 26 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPE 84
Query: 79 TLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPI 138
L LK D+++ G+ ++P ++ L N+ + ++ + + CP + ++ P+
Sbjct: 85 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPV 144
Query: 139 NYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKT 198
N IP+TAE+ + HGVY+ K+FG+T +D +R+ A L VPVIGGH+ KT
Sbjct: 145 NSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKT 204
Query: 199 IVPLLSQAKPTVEMKEKDLEEFTIKLRNCDGMITKAKRGC-IPNLSVAYSSFLFTKSILD 257
I+PL+SQ P V+ + L T +++ + KAK G LS+AY+ F S++D
Sbjct: 205 IIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVD 264
Query: 258 ALEGSPAKIH-AFVDNNDFGTSYFSSLVNLDKNGVKEMVRYSEFSKFECDLIEKSLQQLR 316
A+ G + +FV + + +YFS+ + L K G+++ + + S FE +I ++ +L+
Sbjct: 265 AMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELK 324
Query: 317 KDVSKGRKILE 327
+ KG ++
Sbjct: 325 ASIKKGEDFVK 335
>AC005077-1|AAS07425.1| 316|Homo sapiens unknown protein.
Length = 316
Score = 186 bits (454), Expect = 7e-47
Identities = 93/311 (29%), Positives = 167/311 (53%), Gaps = 3/311 (0%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFTPGVTLDLSQIPSPSRILGLTGED 78
+V V+GA+ +GQ +++L ++D TPGV DLS I + + + G G +
Sbjct: 4 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPE 62
Query: 79 TLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPI 138
L LK D+++ G+ ++P ++ L N+ + ++ + + CP + ++ P+
Sbjct: 63 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPV 122
Query: 139 NYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKT 198
N IP+TAE+ + HGVY+ K+FG+T +D +R+ A L VPVIGGH+ KT
Sbjct: 123 NSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKT 182
Query: 199 IVPLLSQAKPTVEMKEKDLEEFTIKLRNCDGMITKAKRGC-IPNLSVAYSSFLFTKSILD 257
I+PL+SQ P V+ + L T +++ + KAK G LS+AY+ F S++D
Sbjct: 183 IIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVD 242
Query: 258 ALEGSPAKIH-AFVDNNDFGTSYFSSLVNLDKNGVKEMVRYSEFSKFECDLIEKSLQQLR 316
A+ G + +FV + + +YFS+ + L K G+++ + + S FE +I ++ +L+
Sbjct: 243 AMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELK 302
Query: 317 KDVSKGRKILE 327
+ KG ++
Sbjct: 303 ASIKKGEDFVK 313
>DQ402957-1|ABD77290.1| 305|Homo sapiens mitochondrial malate
dehydrogenase 2, NAD protein.
Length = 305
Score = 181 bits (440), Expect = 4e-45
Identities = 91/300 (30%), Positives = 162/300 (54%), Gaps = 3/300 (1%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFTPGVTLDLSQIPSPSRILGLTGED 78
+V V+GA+ +GQ +++L ++D TPGV DLS I + + + G G +
Sbjct: 5 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPE 63
Query: 79 TLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPI 138
L LK D+++ G+ ++P ++ L N+ + ++ + + CP + ++ P+
Sbjct: 64 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPV 123
Query: 139 NYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKT 198
N IP+TAE+ + HGVY+ K+FG+T +D +R+ A L VPVIGGH+ KT
Sbjct: 124 NSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKT 183
Query: 199 IVPLLSQAKPTVEMKEKDLEEFTIKLRNCDGMITKAKRGC-IPNLSVAYSSFLFTKSILD 257
I+PL+SQ P V+ + L T +++ + KAK G LS+AY+ F S++D
Sbjct: 184 IIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVD 243
Query: 258 ALEGSPAKIH-AFVDNNDFGTSYFSSLVNLDKNGVKEMVRYSEFSKFECDLIEKSLQQLR 316
A+ G + +FV + + +YFS+ + L K G+++ + + S FE +I ++ +L+
Sbjct: 244 AMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELK 303
>Y00711-1|CAA68701.1| 334|Homo sapiens protein ( Human mRNA for
lactate dehydrogenase B (LDH-B). ).
Length = 334
Score = 40.3 bits (90), Expect = 0.009
Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145
NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T
Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148
Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199
++ G+ + + +D+ R + L A + + + C+ ++G H D ++
Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199
>X13794-1|CAA32033.1| 334|Homo sapiens lactate dehydrogenase B
protein.
Length = 334
Score = 40.3 bits (90), Expect = 0.009
Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145
NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T
Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148
Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199
++ G+ + + +D+ R + L A + + + C+ ++G H D ++
Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199
>BT019765-1|AAV38570.1| 334|Homo sapiens lactate dehydrogenase B
protein.
Length = 334
Score = 40.3 bits (90), Expect = 0.009
Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145
NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T
Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148
Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199
++ G+ + + +D+ R + L A + + + C+ ++G H D ++
Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199
>BT019764-1|AAV38569.1| 334|Homo sapiens lactate dehydrogenase B
protein.
Length = 334
Score = 40.3 bits (90), Expect = 0.009
Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145
NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T
Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148
Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199
++ G+ + + +D+ R + L A + + + C+ ++G H D ++
Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199
>BC071860-1|AAH71860.1| 334|Homo sapiens lactate dehydrogenase B
protein.
Length = 334
Score = 40.3 bits (90), Expect = 0.009
Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145
NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T
Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148
Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199
++ G+ + + +D+ R + L A + + + C+ ++G H D ++
Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199
>BC015122-1|AAH15122.1| 334|Homo sapiens lactate dehydrogenase B
protein.
Length = 334
Score = 40.3 bits (90), Expect = 0.009
Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145
NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T
Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148
Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199
++ G+ + + +D+ R + L A + + + C+ ++G H D ++
Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199
>BC002362-1|AAH02362.1| 334|Homo sapiens lactate dehydrogenase B
protein.
Length = 334
Score = 40.3 bits (90), Expect = 0.009
Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145
NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T
Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148
Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199
++ G+ + + +D+ R + L A + + + C+ ++G H D ++
Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199
>AY189689-1|AAO85222.1| 334|Homo sapiens transformation-related
protein 5 protein.
Length = 334
Score = 40.3 bits (90), Expect = 0.009
Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145
NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T
Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148
Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199
++ G+ + + +D+ R + L A + + + C+ ++G H D ++
Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199
>U13680-1|AAA21348.1| 332|Homo sapiens lactate dehydrogenase-C
protein.
Length = 332
Score = 39.5 bits (88), Expect = 0.016
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 15/208 (7%)
Query: 3 VNRRIISSLFTTTRSYQ--VTVVGATSEVGQVXXXXXXXXXXITKLVVHDNK-EFTPGVT 59
V ++I L + Q +T+VG T VG +L + D + G
Sbjct: 4 VKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKDLADELALVDVALDKLKGEM 62
Query: 60 LDL---SQIPSPSRILGLTGEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIK 116
+DL S S S+I +G+D A NS ++I G Q+ + AL+ N +K
Sbjct: 63 MDLQHGSLFFSTSKIT--SGKDYSVSA--NSRIVIVTAGARQQEGETRLALVQRNVAIMK 118
Query: 117 SIISKLGRSCPIPFVGIVTEPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYA 176
SII + P + +V+ P++ L T + + G+ + + +D+ R + L
Sbjct: 119 SIIPAIVHYSPDCKILVVSNPVDIL---TYIVWKISGLPVTRVIGSGCNLDSARFRYLIG 175
Query: 177 TENNLKANDCYVPVIGGHSDKTIVPLLS 204
+ + C+ +IG H D + VPL S
Sbjct: 176 EKLGVHPTSCHGWIIGEHGDSS-VPLWS 202
>BC090043-1|AAH90043.1| 332|Homo sapiens lactate dehydrogenase C
protein.
Length = 332
Score = 39.5 bits (88), Expect = 0.016
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 15/208 (7%)
Query: 3 VNRRIISSLFTTTRSYQ--VTVVGATSEVGQVXXXXXXXXXXITKLVVHDNK-EFTPGVT 59
V ++I L + Q +T+VG T VG +L + D + G
Sbjct: 4 VKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKDLADELALVDVALDKLKGEM 62
Query: 60 LDL---SQIPSPSRILGLTGEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIK 116
+DL S S S+I +G+D A NS ++I G Q+ + AL+ N +K
Sbjct: 63 MDLQHGSLFFSTSKIT--SGKDYSVSA--NSRIVIVTAGARQQEGETRLALVQRNVAIMK 118
Query: 117 SIISKLGRSCPIPFVGIVTEPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYA 176
SII + P + +V+ P++ L T + + G+ + + +D+ R + L
Sbjct: 119 SIIPAIVHYSPDCKILVVSNPVDIL---TYIVWKISGLPVTRVIGSGCNLDSARFRYLIG 175
Query: 177 TENNLKANDCYVPVIGGHSDKTIVPLLS 204
+ + C+ +IG H D + VPL S
Sbjct: 176 EKLGVHPTSCHGWIIGEHGDSS-VPLWS 202
>BC064388-1|AAH64388.1| 332|Homo sapiens lactate dehydrogenase C
protein.
Length = 332
Score = 39.5 bits (88), Expect = 0.016
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 15/208 (7%)
Query: 3 VNRRIISSLFTTTRSYQ--VTVVGATSEVGQVXXXXXXXXXXITKLVVHDNK-EFTPGVT 59
V ++I L + Q +T+VG T VG +L + D + G
Sbjct: 4 VKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKDLADELALVDVALDKLKGEM 62
Query: 60 LDL---SQIPSPSRILGLTGEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIK 116
+DL S S S+I +G+D A NS ++I G Q+ + AL+ N +K
Sbjct: 63 MDLQHGSLFFSTSKIT--SGKDYSVSA--NSRIVIVTAGARQQEGETRLALVQRNVAIMK 118
Query: 117 SIISKLGRSCPIPFVGIVTEPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYA 176
SII + P + +V+ P++ L T + + G+ + + +D+ R + L
Sbjct: 119 SIIPAIVHYSPDCKILVVSNPVDIL---TYIVWKISGLPVTRVIGSGCNLDSARFRYLIG 175
Query: 177 TENNLKANDCYVPVIGGHSDKTIVPLLS 204
+ + C+ +IG H D + VPL S
Sbjct: 176 EKLGVHPTSCHGWIIGEHGDSS-VPLWS 202
>BC019249-1|AAH19249.3| 332|Homo sapiens lactate dehydrogenase C
protein.
Length = 332
Score = 39.5 bits (88), Expect = 0.016
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 15/208 (7%)
Query: 3 VNRRIISSLFTTTRSYQ--VTVVGATSEVGQVXXXXXXXXXXITKLVVHDNK-EFTPGVT 59
V ++I L + Q +T+VG T VG +L + D + G
Sbjct: 4 VKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKDLADELALVDVALDKLKGEM 62
Query: 60 LDL---SQIPSPSRILGLTGEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIK 116
+DL S S S+I +G+D A NS ++I G Q+ + AL+ N +K
Sbjct: 63 MDLQHGSLFFSTSKIT--SGKDYSVSA--NSRIVIVTAGARQQEGETRLALVQRNVAIMK 118
Query: 117 SIISKLGRSCPIPFVGIVTEPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYA 176
SII + P + +V+ P++ L T + + G+ + + +D+ R + L
Sbjct: 119 SIIPAIVHYSPDCKILVVSNPVDIL---TYIVWKISGLPVTRVIGSGCNLDSARFRYLIG 175
Query: 177 TENNLKANDCYVPVIGGHSDKTIVPLLS 204
+ + C+ +IG H D + VPL S
Sbjct: 176 EKLGVHPTSCHGWIIGEHGDSS-VPLWS 202
>M24515-1|AAA59508.1| 266|Homo sapiens lactate dehydrogenase-C
protein.
Length = 266
Score = 38.7 bits (86), Expect = 0.028
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145
NS ++I G Q+ + AL+ N +KSII + P + +V+ P++ L T
Sbjct: 46 NSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVDIL---T 102
Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTIVPLLS 204
+ + G+ + + +D+ R + L + + C+ +IG H D + VPL S
Sbjct: 103 YIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSS-VPLWS 160
>AY286300-1|AAP37402.1| 332|Homo sapiens lactate dehydrogenase C
protein.
Length = 332
Score = 38.7 bits (86), Expect = 0.028
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145
NS ++I G Q+ + AL+ N +KSII + P + +V+ P++ L T
Sbjct: 88 NSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVDIL---T 144
Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTIVPLLS 204
+ + G+ + + +D+ R + L + + C+ +IG H D + VPL S
Sbjct: 145 YIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSS-VPLWS 202
>J02938-1|AAA59507.1| 332|Homo sapiens LDHC protein.
Length = 332
Score = 36.7 bits (81), Expect = 0.11
Identities = 50/208 (24%), Positives = 88/208 (42%), Gaps = 15/208 (7%)
Query: 3 VNRRIISSLFTTTRSYQ--VTVVGATSEVGQVXXXXXXXXXXITKLVVHDNK-EFTPGVT 59
V ++I L + Q +T+VG T VG +L + D + G
Sbjct: 4 VKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKDLADELALVDVALDKLKGEM 62
Query: 60 LDL---SQIPSPSRILGLTGEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIK 116
+DL S S S++ +G+D A NS ++I G Q+ + AL+ N +K
Sbjct: 63 MDLQHGSLFFSTSKVT--SGKDYSVSA--NSRIVIVTAGARQQEGETRLALVQRNVAIMK 118
Query: 117 SIISKLGRSCPIPFVGIVTEPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYA 176
II + P + +V+ P++ L T + + G+ + + +D+ R + L
Sbjct: 119 IIIPAIVHYSPDCKILVVSNPVDIL---TYIVWKISGLPVTRVIGSGCNLDSARFRYLIG 175
Query: 177 TENNLKANDCYVPVIGGHSDKTIVPLLS 204
+ + C+ +IG H D + VPL S
Sbjct: 176 EKLGVHPTSCHGWIIGEHGDSS-VPLWS 202
>BC014340-1|AAH14340.1| 234|Homo sapiens LDHAL6A protein protein.
Length = 234
Score = 36.7 bits (81), Expect = 0.11
Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 10/184 (5%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFT-PGVTLDLSQIPSPSRILG--LT 75
++++VG T VG +LV+ D E G T+DL Q SP + ++
Sbjct: 22 KISIVG-TGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDL-QHGSPFMKMPNIVS 79
Query: 76 GEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVT 135
+D L A NS+L+I G Q+ + L+ N K +I + + P + IVT
Sbjct: 80 SKDYLVTA--NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSPHCKLLIVT 137
Query: 136 EPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195
P++ L T + G + + +D+ R + + + C+ ++G H
Sbjct: 138 NPVDIL---TYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGIHSESCHGLILGEHG 194
Query: 196 DKTI 199
D ++
Sbjct: 195 DSSV 198
>AY581313-1|AAS93432.1| 332|Homo sapiens lactate dehydrogenase
protein.
Length = 332
Score = 36.7 bits (81), Expect = 0.11
Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 10/184 (5%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFT-PGVTLDLSQIPSPSRILG--LT 75
++++VG T VG +LV+ D E G T+DL Q SP + ++
Sbjct: 22 KISIVG-TGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDL-QHGSPFMKMPNIVS 79
Query: 76 GEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVT 135
+D L A NS+L+I G Q+ + L+ N K +I + + P + IVT
Sbjct: 80 SKDYLVTA--NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSPHCKLLIVT 137
Query: 136 EPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195
P++ L T + G + + +D+ R + + + C+ ++G H
Sbjct: 138 NPVDIL---TYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGIHSESCHGLILGEHG 194
Query: 196 DKTI 199
D ++
Sbjct: 195 DSSV 198
>AK131523-1|BAD18662.1| 332|Homo sapiens protein ( Homo sapiens
cDNA FLJ43406 fis, clone OCBBF2019823, highly similar
to Homo sapiens lactate dehydrogenase A -like (LDHL). ).
Length = 332
Score = 36.7 bits (81), Expect = 0.11
Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 10/184 (5%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFT-PGVTLDLSQIPSPSRILG--LT 75
++++VG T VG +LV+ D E G T+DL Q SP + ++
Sbjct: 22 KISIVG-TGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDL-QHGSPFMKMPNIVS 79
Query: 76 GEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVT 135
+D L A NS+L+I G Q+ + L+ N K +I + + P + IVT
Sbjct: 80 SKDYLVTA--NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSPHCKLLIVT 137
Query: 136 EPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195
P++ L T + G + + +D+ R + + + C+ ++G H
Sbjct: 138 NPVDIL---TYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGIHSESCHGLILGEHG 194
Query: 196 DKTI 199
D ++
Sbjct: 195 DSSV 198
>BC022034-1|AAH22034.1| 381|Homo sapiens lactate dehydrogenase
A-like 6B protein.
Length = 381
Score = 35.9 bits (79), Expect = 0.20
Identities = 37/184 (20%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHD-NKEFTPGVTLDLSQIPSPSRILGLT-G 76
+V+++G T VG +L + D +++ G T+DL +++ +
Sbjct: 71 KVSIIG-TGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCS 129
Query: 77 EDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTE 136
+D A NS+L+I G Q + L+ N K +IS + + P + IV+
Sbjct: 130 KDYFVTA--NSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSN 187
Query: 137 PINYLIPMTAEIMRNHGVYDEKKLFGI-TEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195
P++ L + ++ + + ++ G +D R + L + + + C+ ++G H
Sbjct: 188 PVDILTYVAWKL----SAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHG 243
Query: 196 DKTI 199
D ++
Sbjct: 244 DSSV 247
>AY642121-1|AAT65080.1| 381|Homo sapiens lactacte dehydrogenase
protein.
Length = 381
Score = 35.9 bits (79), Expect = 0.20
Identities = 37/184 (20%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHD-NKEFTPGVTLDLSQIPSPSRILGLT-G 76
+V+++G T VG +L + D +++ G T+DL +++ +
Sbjct: 71 KVSIIG-TGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCS 129
Query: 77 EDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTE 136
+D A NS+L+I G Q + L+ N K +IS + + P + IV+
Sbjct: 130 KDYFVTA--NSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSN 187
Query: 137 PINYLIPMTAEIMRNHGVYDEKKLFGI-TEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195
P++ L + ++ + + ++ G +D R + L + + + C+ ++G H
Sbjct: 188 PVDILTYVAWKL----SAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHG 243
Query: 196 DKTI 199
D ++
Sbjct: 244 DSSV 247
>AY009108-1|AAG49399.1| 381|Homo sapiens lactate dehydrogenase A
protein.
Length = 381
Score = 35.9 bits (79), Expect = 0.20
Identities = 37/184 (20%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHD-NKEFTPGVTLDLSQIPSPSRILGLT-G 76
+V+++G T VG +L + D +++ G T+DL +++ +
Sbjct: 71 KVSIIG-TGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCS 129
Query: 77 EDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTE 136
+D A NS+L+I G Q + L+ N K +IS + + P + IV+
Sbjct: 130 KDYFVTA--NSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSN 187
Query: 137 PINYLIPMTAEIMRNHGVYDEKKLFGI-TEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195
P++ L + ++ + + ++ G +D R + L + + + C+ ++G H
Sbjct: 188 PVDILTYVAWKL----SAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHG 243
Query: 196 DKTI 199
D ++
Sbjct: 244 DSSV 247
>AK058192-1|BAB71710.1| 381|Homo sapiens protein ( Homo sapiens
cDNA FLJ25463 fis, clone TST09242. ).
Length = 381
Score = 35.9 bits (79), Expect = 0.20
Identities = 37/184 (20%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHD-NKEFTPGVTLDLSQIPSPSRILGLT-G 76
+V+++G T VG +L + D +++ G T+DL +++ +
Sbjct: 71 KVSIIG-TGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCS 129
Query: 77 EDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTE 136
+D A NS+L+I G Q + L+ N K +IS + + P + IV+
Sbjct: 130 KDYFVTA--NSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSN 187
Query: 137 PINYLIPMTAEIMRNHGVYDEKKLFGI-TEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195
P++ L + ++ + + ++ G +D R + L + + + C+ ++G H
Sbjct: 188 PVDILTYVAWKL----SAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHG 243
Query: 196 DKTI 199
D ++
Sbjct: 244 DSSV 247
>AK127961-1|BAC87208.1| 243|Homo sapiens protein ( Homo sapiens
cDNA FLJ46073 fis, clone TESTI2001364, highly similar
to Homo sapiens lactate dehydrogenase A -like (LDHL). ).
Length = 243
Score = 35.5 bits (78), Expect = 0.26
Identities = 40/184 (21%), Positives = 78/184 (42%), Gaps = 10/184 (5%)
Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFT-PGVTLDLSQ-IPSPSRILGLTG 76
+V+++G T VG +L + D E G T+DL P +
Sbjct: 61 KVSIIG-TGSVGMACATSILLKGLSDELALVDLDEGKLKGETMDLQHGSPFMKTPNIVCS 119
Query: 77 EDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTE 136
+D L A NS L+I G Q + L+ N K +IS + + P+ + IV+
Sbjct: 120 KDYLVTA--NSSLVIITEGARQEKGETRLNLVQRNVAIFKLMISGIVQYSPLCKLIIVSN 177
Query: 137 PINYLIPMTAEIMRNHGVYDEKKLFGI-TEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195
P++ L + ++ + + ++ G +D R L+ + + + +C+ ++G H
Sbjct: 178 PVDNLTYVAWKL----SAFSKNRVIGSGCNLDTARFCFLFGQKLGIHSENCHGWILGEHG 233
Query: 196 DKTI 199
D ++
Sbjct: 234 DSSV 237
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.135 0.377
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 41,318,724
Number of Sequences: 224733
Number of extensions: 1578764
Number of successful extensions: 3507
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 3477
Number of HSP's gapped (non-prelim): 28
length of query: 329
length of database: 73,234,838
effective HSP length: 90
effective length of query: 239
effective length of database: 53,008,868
effective search space: 12669119452
effective search space used: 12669119452
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 65 (30.3 bits)
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