BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000994-TA|BGIBMGA000994-PA|IPR010097|Malate dehydrogenase, NAD-dependent, eukaryotes and gamma proteobacteria, IPR001236|Lactate/malate dehydrogenase (329 letters) Database: human 224,733 sequences; 73,234,838 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CR536548-1|CAG38785.1| 338|Homo sapiens MDH2 protein. 186 7e-47 BC001917-1|AAH01917.1| 338|Homo sapiens malate dehydrogenase 2,... 186 7e-47 AF047470-1|AAC03787.1| 338|Homo sapiens malate dehydrogenase pr... 186 7e-47 AC005077-1|AAS07425.1| 316|Homo sapiens unknown protein. 186 7e-47 DQ402957-1|ABD77290.1| 305|Homo sapiens mitochondrial malate de... 181 4e-45 Y00711-1|CAA68701.1| 334|Homo sapiens protein ( Human mRNA for ... 40 0.009 X13794-1|CAA32033.1| 334|Homo sapiens lactate dehydrogenase B p... 40 0.009 BT019765-1|AAV38570.1| 334|Homo sapiens lactate dehydrogenase B... 40 0.009 BT019764-1|AAV38569.1| 334|Homo sapiens lactate dehydrogenase B... 40 0.009 BC071860-1|AAH71860.1| 334|Homo sapiens lactate dehydrogenase B... 40 0.009 BC015122-1|AAH15122.1| 334|Homo sapiens lactate dehydrogenase B... 40 0.009 BC002362-1|AAH02362.1| 334|Homo sapiens lactate dehydrogenase B... 40 0.009 AY189689-1|AAO85222.1| 334|Homo sapiens transformation-related ... 40 0.009 U13680-1|AAA21348.1| 332|Homo sapiens lactate dehydrogenase-C p... 40 0.016 BC090043-1|AAH90043.1| 332|Homo sapiens lactate dehydrogenase C... 40 0.016 BC064388-1|AAH64388.1| 332|Homo sapiens lactate dehydrogenase C... 40 0.016 BC019249-1|AAH19249.3| 332|Homo sapiens lactate dehydrogenase C... 40 0.016 M24515-1|AAA59508.1| 266|Homo sapiens lactate dehydrogenase-C p... 39 0.028 AY286300-1|AAP37402.1| 332|Homo sapiens lactate dehydrogenase C... 39 0.028 J02938-1|AAA59507.1| 332|Homo sapiens LDHC protein. 37 0.11 BC014340-1|AAH14340.1| 234|Homo sapiens LDHAL6A protein protein. 37 0.11 AY581313-1|AAS93432.1| 332|Homo sapiens lactate dehydrogenase p... 37 0.11 AK131523-1|BAD18662.1| 332|Homo sapiens protein ( Homo sapiens ... 37 0.11 BC022034-1|AAH22034.1| 381|Homo sapiens lactate dehydrogenase A... 36 0.20 AY642121-1|AAT65080.1| 381|Homo sapiens lactacte dehydrogenase ... 36 0.20 AY009108-1|AAG49399.1| 381|Homo sapiens lactate dehydrogenase A... 36 0.20 AK058192-1|BAB71710.1| 381|Homo sapiens protein ( Homo sapiens ... 36 0.20 AK127961-1|BAC87208.1| 243|Homo sapiens protein ( Homo sapiens ... 36 0.26 >CR536548-1|CAG38785.1| 338|Homo sapiens MDH2 protein. Length = 338 Score = 186 bits (454), Expect = 7e-47 Identities = 93/311 (29%), Positives = 167/311 (53%), Gaps = 3/311 (0%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFTPGVTLDLSQIPSPSRILGLTGED 78 +V V+GA+ +GQ +++L ++D TPGV DLS I + + + G G + Sbjct: 26 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPE 84 Query: 79 TLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPI 138 L LK D+++ G+ ++P ++ L N+ + ++ + + CP + ++ P+ Sbjct: 85 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPV 144 Query: 139 NYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKT 198 N IP+TAE+ + HGVY+ K+FG+T +D +R+ A L VPVIGGH+ KT Sbjct: 145 NSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKT 204 Query: 199 IVPLLSQAKPTVEMKEKDLEEFTIKLRNCDGMITKAKRGC-IPNLSVAYSSFLFTKSILD 257 I+PL+SQ P V+ + L T +++ + KAK G LS+AY+ F S++D Sbjct: 205 IIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVD 264 Query: 258 ALEGSPAKIH-AFVDNNDFGTSYFSSLVNLDKNGVKEMVRYSEFSKFECDLIEKSLQQLR 316 A+ G + +FV + + +YFS+ + L K G+++ + + S FE +I ++ +L+ Sbjct: 265 AMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELK 324 Query: 317 KDVSKGRKILE 327 + KG ++ Sbjct: 325 ASIKKGEDFVK 335 >BC001917-1|AAH01917.1| 338|Homo sapiens malate dehydrogenase 2, NAD (mitochondrial) protein. Length = 338 Score = 186 bits (454), Expect = 7e-47 Identities = 93/311 (29%), Positives = 167/311 (53%), Gaps = 3/311 (0%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFTPGVTLDLSQIPSPSRILGLTGED 78 +V V+GA+ +GQ +++L ++D TPGV DLS I + + + G G + Sbjct: 26 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPE 84 Query: 79 TLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPI 138 L LK D+++ G+ ++P ++ L N+ + ++ + + CP + ++ P+ Sbjct: 85 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPV 144 Query: 139 NYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKT 198 N IP+TAE+ + HGVY+ K+FG+T +D +R+ A L VPVIGGH+ KT Sbjct: 145 NSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKT 204 Query: 199 IVPLLSQAKPTVEMKEKDLEEFTIKLRNCDGMITKAKRGC-IPNLSVAYSSFLFTKSILD 257 I+PL+SQ P V+ + L T +++ + KAK G LS+AY+ F S++D Sbjct: 205 IIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVD 264 Query: 258 ALEGSPAKIH-AFVDNNDFGTSYFSSLVNLDKNGVKEMVRYSEFSKFECDLIEKSLQQLR 316 A+ G + +FV + + +YFS+ + L K G+++ + + S FE +I ++ +L+ Sbjct: 265 AMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELK 324 Query: 317 KDVSKGRKILE 327 + KG ++ Sbjct: 325 ASIKKGEDFVK 335 >AF047470-1|AAC03787.1| 338|Homo sapiens malate dehydrogenase precursor protein. Length = 338 Score = 186 bits (454), Expect = 7e-47 Identities = 93/311 (29%), Positives = 167/311 (53%), Gaps = 3/311 (0%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFTPGVTLDLSQIPSPSRILGLTGED 78 +V V+GA+ +GQ +++L ++D TPGV DLS I + + + G G + Sbjct: 26 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPE 84 Query: 79 TLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPI 138 L LK D+++ G+ ++P ++ L N+ + ++ + + CP + ++ P+ Sbjct: 85 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPV 144 Query: 139 NYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKT 198 N IP+TAE+ + HGVY+ K+FG+T +D +R+ A L VPVIGGH+ KT Sbjct: 145 NSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKT 204 Query: 199 IVPLLSQAKPTVEMKEKDLEEFTIKLRNCDGMITKAKRGC-IPNLSVAYSSFLFTKSILD 257 I+PL+SQ P V+ + L T +++ + KAK G LS+AY+ F S++D Sbjct: 205 IIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVD 264 Query: 258 ALEGSPAKIH-AFVDNNDFGTSYFSSLVNLDKNGVKEMVRYSEFSKFECDLIEKSLQQLR 316 A+ G + +FV + + +YFS+ + L K G+++ + + S FE +I ++ +L+ Sbjct: 265 AMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELK 324 Query: 317 KDVSKGRKILE 327 + KG ++ Sbjct: 325 ASIKKGEDFVK 335 >AC005077-1|AAS07425.1| 316|Homo sapiens unknown protein. Length = 316 Score = 186 bits (454), Expect = 7e-47 Identities = 93/311 (29%), Positives = 167/311 (53%), Gaps = 3/311 (0%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFTPGVTLDLSQIPSPSRILGLTGED 78 +V V+GA+ +GQ +++L ++D TPGV DLS I + + + G G + Sbjct: 4 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPE 62 Query: 79 TLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPI 138 L LK D+++ G+ ++P ++ L N+ + ++ + + CP + ++ P+ Sbjct: 63 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPV 122 Query: 139 NYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKT 198 N IP+TAE+ + HGVY+ K+FG+T +D +R+ A L VPVIGGH+ KT Sbjct: 123 NSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKT 182 Query: 199 IVPLLSQAKPTVEMKEKDLEEFTIKLRNCDGMITKAKRGC-IPNLSVAYSSFLFTKSILD 257 I+PL+SQ P V+ + L T +++ + KAK G LS+AY+ F S++D Sbjct: 183 IIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVD 242 Query: 258 ALEGSPAKIH-AFVDNNDFGTSYFSSLVNLDKNGVKEMVRYSEFSKFECDLIEKSLQQLR 316 A+ G + +FV + + +YFS+ + L K G+++ + + S FE +I ++ +L+ Sbjct: 243 AMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELK 302 Query: 317 KDVSKGRKILE 327 + KG ++ Sbjct: 303 ASIKKGEDFVK 313 >DQ402957-1|ABD77290.1| 305|Homo sapiens mitochondrial malate dehydrogenase 2, NAD protein. Length = 305 Score = 181 bits (440), Expect = 4e-45 Identities = 91/300 (30%), Positives = 162/300 (54%), Gaps = 3/300 (1%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFTPGVTLDLSQIPSPSRILGLTGED 78 +V V+GA+ +GQ +++L ++D TPGV DLS I + + + G G + Sbjct: 5 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPE 63 Query: 79 TLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPI 138 L LK D+++ G+ ++P ++ L N+ + ++ + + CP + ++ P+ Sbjct: 64 QLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPV 123 Query: 139 NYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKT 198 N IP+TAE+ + HGVY+ K+FG+T +D +R+ A L VPVIGGH+ KT Sbjct: 124 NSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKT 183 Query: 199 IVPLLSQAKPTVEMKEKDLEEFTIKLRNCDGMITKAKRGC-IPNLSVAYSSFLFTKSILD 257 I+PL+SQ P V+ + L T +++ + KAK G LS+AY+ F S++D Sbjct: 184 IIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVD 243 Query: 258 ALEGSPAKIH-AFVDNNDFGTSYFSSLVNLDKNGVKEMVRYSEFSKFECDLIEKSLQQLR 316 A+ G + +FV + + +YFS+ + L K G+++ + + S FE +I ++ +L+ Sbjct: 244 AMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELK 303 >Y00711-1|CAA68701.1| 334|Homo sapiens protein ( Human mRNA for lactate dehydrogenase B (LDH-B). ). Length = 334 Score = 40.3 bits (90), Expect = 0.009 Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%) Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145 NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148 Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199 ++ G+ + + +D+ R + L A + + + C+ ++G H D ++ Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199 >X13794-1|CAA32033.1| 334|Homo sapiens lactate dehydrogenase B protein. Length = 334 Score = 40.3 bits (90), Expect = 0.009 Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%) Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145 NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148 Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199 ++ G+ + + +D+ R + L A + + + C+ ++G H D ++ Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199 >BT019765-1|AAV38570.1| 334|Homo sapiens lactate dehydrogenase B protein. Length = 334 Score = 40.3 bits (90), Expect = 0.009 Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%) Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145 NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148 Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199 ++ G+ + + +D+ R + L A + + + C+ ++G H D ++ Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199 >BT019764-1|AAV38569.1| 334|Homo sapiens lactate dehydrogenase B protein. Length = 334 Score = 40.3 bits (90), Expect = 0.009 Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%) Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145 NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148 Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199 ++ G+ + + +D+ R + L A + + + C+ ++G H D ++ Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199 >BC071860-1|AAH71860.1| 334|Homo sapiens lactate dehydrogenase B protein. Length = 334 Score = 40.3 bits (90), Expect = 0.009 Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%) Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145 NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148 Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199 ++ G+ + + +D+ R + L A + + + C+ ++G H D ++ Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199 >BC015122-1|AAH15122.1| 334|Homo sapiens lactate dehydrogenase B protein. Length = 334 Score = 40.3 bits (90), Expect = 0.009 Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%) Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145 NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148 Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199 ++ G+ + + +D+ R + L A + + + C+ ++G H D ++ Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199 >BC002362-1|AAH02362.1| 334|Homo sapiens lactate dehydrogenase B protein. Length = 334 Score = 40.3 bits (90), Expect = 0.009 Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%) Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145 NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148 Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199 ++ G+ + + +D+ R + L A + + + C+ ++G H D ++ Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199 >AY189689-1|AAO85222.1| 334|Homo sapiens transformation-related protein 5 protein. Length = 334 Score = 40.3 bits (90), Expect = 0.009 Identities = 24/114 (21%), Positives = 55/114 (48%), Gaps = 3/114 (2%) Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145 NS +++ G+ Q+ S L+ N K II ++ + P + +V+ P++ L +T Sbjct: 89 NSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT 148 Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTI 199 ++ G+ + + +D+ R + L A + + + C+ ++G H D ++ Sbjct: 149 WKLS---GLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSV 199 >U13680-1|AAA21348.1| 332|Homo sapiens lactate dehydrogenase-C protein. Length = 332 Score = 39.5 bits (88), Expect = 0.016 Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 15/208 (7%) Query: 3 VNRRIISSLFTTTRSYQ--VTVVGATSEVGQVXXXXXXXXXXITKLVVHDNK-EFTPGVT 59 V ++I L + Q +T+VG T VG +L + D + G Sbjct: 4 VKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKDLADELALVDVALDKLKGEM 62 Query: 60 LDL---SQIPSPSRILGLTGEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIK 116 +DL S S S+I +G+D A NS ++I G Q+ + AL+ N +K Sbjct: 63 MDLQHGSLFFSTSKIT--SGKDYSVSA--NSRIVIVTAGARQQEGETRLALVQRNVAIMK 118 Query: 117 SIISKLGRSCPIPFVGIVTEPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYA 176 SII + P + +V+ P++ L T + + G+ + + +D+ R + L Sbjct: 119 SIIPAIVHYSPDCKILVVSNPVDIL---TYIVWKISGLPVTRVIGSGCNLDSARFRYLIG 175 Query: 177 TENNLKANDCYVPVIGGHSDKTIVPLLS 204 + + C+ +IG H D + VPL S Sbjct: 176 EKLGVHPTSCHGWIIGEHGDSS-VPLWS 202 >BC090043-1|AAH90043.1| 332|Homo sapiens lactate dehydrogenase C protein. Length = 332 Score = 39.5 bits (88), Expect = 0.016 Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 15/208 (7%) Query: 3 VNRRIISSLFTTTRSYQ--VTVVGATSEVGQVXXXXXXXXXXITKLVVHDNK-EFTPGVT 59 V ++I L + Q +T+VG T VG +L + D + G Sbjct: 4 VKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKDLADELALVDVALDKLKGEM 62 Query: 60 LDL---SQIPSPSRILGLTGEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIK 116 +DL S S S+I +G+D A NS ++I G Q+ + AL+ N +K Sbjct: 63 MDLQHGSLFFSTSKIT--SGKDYSVSA--NSRIVIVTAGARQQEGETRLALVQRNVAIMK 118 Query: 117 SIISKLGRSCPIPFVGIVTEPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYA 176 SII + P + +V+ P++ L T + + G+ + + +D+ R + L Sbjct: 119 SIIPAIVHYSPDCKILVVSNPVDIL---TYIVWKISGLPVTRVIGSGCNLDSARFRYLIG 175 Query: 177 TENNLKANDCYVPVIGGHSDKTIVPLLS 204 + + C+ +IG H D + VPL S Sbjct: 176 EKLGVHPTSCHGWIIGEHGDSS-VPLWS 202 >BC064388-1|AAH64388.1| 332|Homo sapiens lactate dehydrogenase C protein. Length = 332 Score = 39.5 bits (88), Expect = 0.016 Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 15/208 (7%) Query: 3 VNRRIISSLFTTTRSYQ--VTVVGATSEVGQVXXXXXXXXXXITKLVVHDNK-EFTPGVT 59 V ++I L + Q +T+VG T VG +L + D + G Sbjct: 4 VKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKDLADELALVDVALDKLKGEM 62 Query: 60 LDL---SQIPSPSRILGLTGEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIK 116 +DL S S S+I +G+D A NS ++I G Q+ + AL+ N +K Sbjct: 63 MDLQHGSLFFSTSKIT--SGKDYSVSA--NSRIVIVTAGARQQEGETRLALVQRNVAIMK 118 Query: 117 SIISKLGRSCPIPFVGIVTEPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYA 176 SII + P + +V+ P++ L T + + G+ + + +D+ R + L Sbjct: 119 SIIPAIVHYSPDCKILVVSNPVDIL---TYIVWKISGLPVTRVIGSGCNLDSARFRYLIG 175 Query: 177 TENNLKANDCYVPVIGGHSDKTIVPLLS 204 + + C+ +IG H D + VPL S Sbjct: 176 EKLGVHPTSCHGWIIGEHGDSS-VPLWS 202 >BC019249-1|AAH19249.3| 332|Homo sapiens lactate dehydrogenase C protein. Length = 332 Score = 39.5 bits (88), Expect = 0.016 Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 15/208 (7%) Query: 3 VNRRIISSLFTTTRSYQ--VTVVGATSEVGQVXXXXXXXXXXITKLVVHDNK-EFTPGVT 59 V ++I L + Q +T+VG T VG +L + D + G Sbjct: 4 VKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKDLADELALVDVALDKLKGEM 62 Query: 60 LDL---SQIPSPSRILGLTGEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIK 116 +DL S S S+I +G+D A NS ++I G Q+ + AL+ N +K Sbjct: 63 MDLQHGSLFFSTSKIT--SGKDYSVSA--NSRIVIVTAGARQQEGETRLALVQRNVAIMK 118 Query: 117 SIISKLGRSCPIPFVGIVTEPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYA 176 SII + P + +V+ P++ L T + + G+ + + +D+ R + L Sbjct: 119 SIIPAIVHYSPDCKILVVSNPVDIL---TYIVWKISGLPVTRVIGSGCNLDSARFRYLIG 175 Query: 177 TENNLKANDCYVPVIGGHSDKTIVPLLS 204 + + C+ +IG H D + VPL S Sbjct: 176 EKLGVHPTSCHGWIIGEHGDSS-VPLWS 202 >M24515-1|AAA59508.1| 266|Homo sapiens lactate dehydrogenase-C protein. Length = 266 Score = 38.7 bits (86), Expect = 0.028 Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 4/119 (3%) Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145 NS ++I G Q+ + AL+ N +KSII + P + +V+ P++ L T Sbjct: 46 NSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVDIL---T 102 Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTIVPLLS 204 + + G+ + + +D+ R + L + + C+ +IG H D + VPL S Sbjct: 103 YIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSS-VPLWS 160 >AY286300-1|AAP37402.1| 332|Homo sapiens lactate dehydrogenase C protein. Length = 332 Score = 38.7 bits (86), Expect = 0.028 Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 4/119 (3%) Query: 86 NSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTEPINYLIPMT 145 NS ++I G Q+ + AL+ N +KSII + P + +V+ P++ L T Sbjct: 88 NSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVDIL---T 144 Query: 146 AEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHSDKTIVPLLS 204 + + G+ + + +D+ R + L + + C+ +IG H D + VPL S Sbjct: 145 YIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSS-VPLWS 202 >J02938-1|AAA59507.1| 332|Homo sapiens LDHC protein. Length = 332 Score = 36.7 bits (81), Expect = 0.11 Identities = 50/208 (24%), Positives = 88/208 (42%), Gaps = 15/208 (7%) Query: 3 VNRRIISSLFTTTRSYQ--VTVVGATSEVGQVXXXXXXXXXXITKLVVHDNK-EFTPGVT 59 V ++I L + Q +T+VG T VG +L + D + G Sbjct: 4 VKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKDLADELALVDVALDKLKGEM 62 Query: 60 LDL---SQIPSPSRILGLTGEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIK 116 +DL S S S++ +G+D A NS ++I G Q+ + AL+ N +K Sbjct: 63 MDLQHGSLFFSTSKVT--SGKDYSVSA--NSRIVIVTAGARQQEGETRLALVQRNVAIMK 118 Query: 117 SIISKLGRSCPIPFVGIVTEPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYA 176 II + P + +V+ P++ L T + + G+ + + +D+ R + L Sbjct: 119 IIIPAIVHYSPDCKILVVSNPVDIL---TYIVWKISGLPVTRVIGSGCNLDSARFRYLIG 175 Query: 177 TENNLKANDCYVPVIGGHSDKTIVPLLS 204 + + C+ +IG H D + VPL S Sbjct: 176 EKLGVHPTSCHGWIIGEHGDSS-VPLWS 202 >BC014340-1|AAH14340.1| 234|Homo sapiens LDHAL6A protein protein. Length = 234 Score = 36.7 bits (81), Expect = 0.11 Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 10/184 (5%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFT-PGVTLDLSQIPSPSRILG--LT 75 ++++VG T VG +LV+ D E G T+DL Q SP + ++ Sbjct: 22 KISIVG-TGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDL-QHGSPFMKMPNIVS 79 Query: 76 GEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVT 135 +D L A NS+L+I G Q+ + L+ N K +I + + P + IVT Sbjct: 80 SKDYLVTA--NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSPHCKLLIVT 137 Query: 136 EPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195 P++ L T + G + + +D+ R + + + C+ ++G H Sbjct: 138 NPVDIL---TYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGIHSESCHGLILGEHG 194 Query: 196 DKTI 199 D ++ Sbjct: 195 DSSV 198 >AY581313-1|AAS93432.1| 332|Homo sapiens lactate dehydrogenase protein. Length = 332 Score = 36.7 bits (81), Expect = 0.11 Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 10/184 (5%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFT-PGVTLDLSQIPSPSRILG--LT 75 ++++VG T VG +LV+ D E G T+DL Q SP + ++ Sbjct: 22 KISIVG-TGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDL-QHGSPFMKMPNIVS 79 Query: 76 GEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVT 135 +D L A NS+L+I G Q+ + L+ N K +I + + P + IVT Sbjct: 80 SKDYLVTA--NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSPHCKLLIVT 137 Query: 136 EPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195 P++ L T + G + + +D+ R + + + C+ ++G H Sbjct: 138 NPVDIL---TYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGIHSESCHGLILGEHG 194 Query: 196 DKTI 199 D ++ Sbjct: 195 DSSV 198 >AK131523-1|BAD18662.1| 332|Homo sapiens protein ( Homo sapiens cDNA FLJ43406 fis, clone OCBBF2019823, highly similar to Homo sapiens lactate dehydrogenase A -like (LDHL). ). Length = 332 Score = 36.7 bits (81), Expect = 0.11 Identities = 43/184 (23%), Positives = 78/184 (42%), Gaps = 10/184 (5%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFT-PGVTLDLSQIPSPSRILG--LT 75 ++++VG T VG +LV+ D E G T+DL Q SP + ++ Sbjct: 22 KISIVG-TGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDL-QHGSPFMKMPNIVS 79 Query: 76 GEDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVT 135 +D L A NS+L+I G Q+ + L+ N K +I + + P + IVT Sbjct: 80 SKDYLVTA--NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSPHCKLLIVT 137 Query: 136 EPINYLIPMTAEIMRNHGVYDEKKLFGITEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195 P++ L T + G + + +D+ R + + + C+ ++G H Sbjct: 138 NPVDIL---TYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGIHSESCHGLILGEHG 194 Query: 196 DKTI 199 D ++ Sbjct: 195 DSSV 198 >BC022034-1|AAH22034.1| 381|Homo sapiens lactate dehydrogenase A-like 6B protein. Length = 381 Score = 35.9 bits (79), Expect = 0.20 Identities = 37/184 (20%), Positives = 80/184 (43%), Gaps = 10/184 (5%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHD-NKEFTPGVTLDLSQIPSPSRILGLT-G 76 +V+++G T VG +L + D +++ G T+DL +++ + Sbjct: 71 KVSIIG-TGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCS 129 Query: 77 EDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTE 136 +D A NS+L+I G Q + L+ N K +IS + + P + IV+ Sbjct: 130 KDYFVTA--NSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSN 187 Query: 137 PINYLIPMTAEIMRNHGVYDEKKLFGI-TEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195 P++ L + ++ + + ++ G +D R + L + + + C+ ++G H Sbjct: 188 PVDILTYVAWKL----SAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHG 243 Query: 196 DKTI 199 D ++ Sbjct: 244 DSSV 247 >AY642121-1|AAT65080.1| 381|Homo sapiens lactacte dehydrogenase protein. Length = 381 Score = 35.9 bits (79), Expect = 0.20 Identities = 37/184 (20%), Positives = 80/184 (43%), Gaps = 10/184 (5%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHD-NKEFTPGVTLDLSQIPSPSRILGLT-G 76 +V+++G T VG +L + D +++ G T+DL +++ + Sbjct: 71 KVSIIG-TGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCS 129 Query: 77 EDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTE 136 +D A NS+L+I G Q + L+ N K +IS + + P + IV+ Sbjct: 130 KDYFVTA--NSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSN 187 Query: 137 PINYLIPMTAEIMRNHGVYDEKKLFGI-TEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195 P++ L + ++ + + ++ G +D R + L + + + C+ ++G H Sbjct: 188 PVDILTYVAWKL----SAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHG 243 Query: 196 DKTI 199 D ++ Sbjct: 244 DSSV 247 >AY009108-1|AAG49399.1| 381|Homo sapiens lactate dehydrogenase A protein. Length = 381 Score = 35.9 bits (79), Expect = 0.20 Identities = 37/184 (20%), Positives = 80/184 (43%), Gaps = 10/184 (5%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHD-NKEFTPGVTLDLSQIPSPSRILGLT-G 76 +V+++G T VG +L + D +++ G T+DL +++ + Sbjct: 71 KVSIIG-TGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCS 129 Query: 77 EDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTE 136 +D A NS+L+I G Q + L+ N K +IS + + P + IV+ Sbjct: 130 KDYFVTA--NSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSN 187 Query: 137 PINYLIPMTAEIMRNHGVYDEKKLFGI-TEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195 P++ L + ++ + + ++ G +D R + L + + + C+ ++G H Sbjct: 188 PVDILTYVAWKL----SAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHG 243 Query: 196 DKTI 199 D ++ Sbjct: 244 DSSV 247 >AK058192-1|BAB71710.1| 381|Homo sapiens protein ( Homo sapiens cDNA FLJ25463 fis, clone TST09242. ). Length = 381 Score = 35.9 bits (79), Expect = 0.20 Identities = 37/184 (20%), Positives = 80/184 (43%), Gaps = 10/184 (5%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHD-NKEFTPGVTLDLSQIPSPSRILGLT-G 76 +V+++G T VG +L + D +++ G T+DL +++ + Sbjct: 71 KVSIIG-TGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCS 129 Query: 77 EDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTE 136 +D A NS+L+I G Q + L+ N K +IS + + P + IV+ Sbjct: 130 KDYFVTA--NSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSN 187 Query: 137 PINYLIPMTAEIMRNHGVYDEKKLFGI-TEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195 P++ L + ++ + + ++ G +D R + L + + + C+ ++G H Sbjct: 188 PVDILTYVAWKL----SAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHG 243 Query: 196 DKTI 199 D ++ Sbjct: 244 DSSV 247 >AK127961-1|BAC87208.1| 243|Homo sapiens protein ( Homo sapiens cDNA FLJ46073 fis, clone TESTI2001364, highly similar to Homo sapiens lactate dehydrogenase A -like (LDHL). ). Length = 243 Score = 35.5 bits (78), Expect = 0.26 Identities = 40/184 (21%), Positives = 78/184 (42%), Gaps = 10/184 (5%) Query: 19 QVTVVGATSEVGQVXXXXXXXXXXITKLVVHDNKEFT-PGVTLDLSQ-IPSPSRILGLTG 76 +V+++G T VG +L + D E G T+DL P + Sbjct: 61 KVSIIG-TGSVGMACATSILLKGLSDELALVDLDEGKLKGETMDLQHGSPFMKTPNIVCS 119 Query: 77 EDTLERALKNSDLIIAAGGLSQRPDISEKALLTANSQFIKSIISKLGRSCPIPFVGIVTE 136 +D L A NS L+I G Q + L+ N K +IS + + P+ + IV+ Sbjct: 120 KDYLVTA--NSSLVIITEGARQEKGETRLNLVQRNVAIFKLMISGIVQYSPLCKLIIVSN 177 Query: 137 PINYLIPMTAEIMRNHGVYDEKKLFGI-TEIDAIRSQCLYATENNLKANDCYVPVIGGHS 195 P++ L + ++ + + ++ G +D R L+ + + + +C+ ++G H Sbjct: 178 PVDNLTYVAWKL----SAFSKNRVIGSGCNLDTARFCFLFGQKLGIHSENCHGWILGEHG 233 Query: 196 DKTI 199 D ++ Sbjct: 234 DSSV 237 Database: human Posted date: Oct 5, 2007 11:13 AM Number of letters in database: 73,234,838 Number of sequences in database: 224,733 Lambda K H 0.318 0.135 0.377 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 41,318,724 Number of Sequences: 224733 Number of extensions: 1578764 Number of successful extensions: 3507 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 5 Number of HSP's successfully gapped in prelim test: 23 Number of HSP's that attempted gapping in prelim test: 3477 Number of HSP's gapped (non-prelim): 28 length of query: 329 length of database: 73,234,838 effective HSP length: 90 effective length of query: 239 effective length of database: 53,008,868 effective search space: 12669119452 effective search space used: 12669119452 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits) S2: 65 (30.3 bits)
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