BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000991-TA|BGIBMGA000991-PA|IPR004154|Anticodon-binding, IPR009068|S15/NS1, RNA-binding, IPR010987|Glutathione S-transferase, C-terminal-like, IPR000738|WHEP-TRS (491 letters) Database: human 224,733 sequences; 73,234,838 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AY995220-1|AAX99363.1| 509|Homo sapiens histidyl-tRNA synthetas... 212 2e-54 Z11518-1|CAA77607.1| 509|Homo sapiens histidyl-tRNA synthetase ... 212 3e-54 BC080514-1|AAH80514.1| 509|Homo sapiens histidyl-tRNA synthetas... 212 3e-54 BC011807-1|AAH11807.1| 509|Homo sapiens histidyl-tRNA synthetas... 212 3e-54 X05345-1|CAA28956.1| 508|Homo sapiens protein ( Human mRNA for ... 209 2e-53 U18937-1|AAA73974.1| 506|Homo sapiens histidyl-tRNA synthetase ... 207 8e-53 BC014982-1|AAH14982.1| 506|Homo sapiens histidyl-tRNA synthetas... 207 8e-53 BC007680-1|AAH07680.1| 506|Homo sapiens histidyl-tRNA synthetas... 207 8e-53 X60656-1|CAA43063.1| 225|Homo sapiens elongation factor 1-beta ... 46 3e-04 X60489-1|CAA43019.1| 225|Homo sapiens elongation factor-1-beta ... 46 3e-04 CR456825-1|CAG33106.1| 225|Homo sapiens EEF1B2 protein. 46 3e-04 BT007079-1|AAP35742.1| 225|Homo sapiens eukaryotic translation ... 46 3e-04 BC067787-1|AAH67787.1| 225|Homo sapiens eukaryotic translation ... 46 3e-04 BC004931-1|AAH04931.1| 225|Homo sapiens eukaryotic translation ... 46 3e-04 BC000211-1|AAH00211.1| 225|Homo sapiens eukaryotic translation ... 46 3e-04 AC007383-2|AAY15062.1| 225|Homo sapiens unknown protein. 46 3e-04 BC009350-1|AAH09350.2| 829|Homo sapiens EIF2AK4 protein protein. 43 0.003 AL157497-1|CAB75678.1| 938|Homo sapiens hypothetical protein pr... 43 0.003 AK027011-1|BAB15625.1| 806|Homo sapiens protein ( Homo sapiens ... 43 0.003 AJ243428-1|CAB58360.1| 548|Homo sapiens putative eIF2 alpha kin... 43 0.003 AB037759-1|BAA92576.1| 1495|Homo sapiens KIAA1338 protein protein. 43 0.003 AK125242-1|BAC86097.1| 307|Homo sapiens protein ( Homo sapiens ... 32 4.0 >AY995220-1|AAX99363.1| 509|Homo sapiens histidyl-tRNA synthetase protein. Length = 509 Score = 212 bits (518), Expect = 2e-54 Identities = 99/166 (59%), Positives = 120/166 (72%) Query: 191 DFDIAGIYDPMVPDAECLKVVTEILEALDIGQYILKVNHRRLLDGMFEACGVPADKFRTT 250 DFDIAG +DPM+PDAECLK++ EIL +L IG +++KVN RR+LDGMF CGV KFRT Sbjct: 175 DFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTI 234 Query: 251 CSTVDKLDKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXXXXXXA 310 CS+VDKLDK WEEV+ EM+ EKG++P+ ADRIG+Y + +G Sbjct: 235 CSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLAEQLLQDPKLSQNKQ 294 Query: 311 ALEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAVL 356 ALEG+ +K L +Y LFGI DKI FDLSLARGLDYYTGVIYEAVL Sbjct: 295 ALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVL 340 Score = 156 bits (378), Expect = 2e-37 Identities = 72/120 (60%), Positives = 96/120 (80%) Query: 359 VSIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQS 418 +SIGVERIFS++E +L A + +RT++ V VASAQK LEER+K+ +ELWDAGIK E Sbjct: 382 LSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELL 441 Query: 419 YKKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKR 478 YKKNPK+LNQLQ+CEE PL ++G+ ELK GV+K+R++T+REE +V R DLV+EIK+R Sbjct: 442 YKKNPKLLNQLQYCEEAGTPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRR 501 Score = 99 bits (238), Expect = 2e-20 Identities = 48/72 (66%), Positives = 56/72 (77%), Gaps = 1/72 (1%) Query: 120 VKEEVSKLLALKAQLVTEDAGPQKFTLKTPKGTRDYNPQQMTIRNNVLDKIITVFRRHGA 179 ++EEV+KLL LKAQL D QKF LKTPKGTRDY+P+QM +R V D II F+RHGA Sbjct: 31 IEEEVAKLLKLKAQL-GPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGA 89 Query: 180 ECIDTPVFELKD 191 E IDTPVFELK+ Sbjct: 90 EVIDTPVFELKE 101 >Z11518-1|CAA77607.1| 509|Homo sapiens histidyl-tRNA synthetase protein. Length = 509 Score = 212 bits (517), Expect = 3e-54 Identities = 99/166 (59%), Positives = 120/166 (72%) Query: 191 DFDIAGIYDPMVPDAECLKVVTEILEALDIGQYILKVNHRRLLDGMFEACGVPADKFRTT 250 DFDIAG +DPM+PDAECLK++ EIL +L IG +++KVN RR+LDGMF CGV KFRT Sbjct: 175 DFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTI 234 Query: 251 CSTVDKLDKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXXXXXXA 310 CS+VDKLDK WEEV+ EM+ EKG++P+ ADRIG+Y + +G Sbjct: 235 CSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQ 294 Query: 311 ALEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAVL 356 ALEG+ +K L +Y LFGI DKI FDLSLARGLDYYTGVIYEAVL Sbjct: 295 ALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVL 340 Score = 158 bits (383), Expect = 5e-38 Identities = 73/120 (60%), Positives = 97/120 (80%) Query: 359 VSIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQS 418 +SIGVERIFS++E +L A + +RT++ V VASAQK LEER+K+ +ELWDAGIK E Sbjct: 382 LSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELL 441 Query: 419 YKKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKR 478 YKKNPK+LNQLQ+CEE IPL ++G+ ELK GV+K+R++T+REE +V R DLV+EIK+R Sbjct: 442 YKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRR 501 Score = 99 bits (238), Expect = 2e-20 Identities = 48/72 (66%), Positives = 56/72 (77%), Gaps = 1/72 (1%) Query: 120 VKEEVSKLLALKAQLVTEDAGPQKFTLKTPKGTRDYNPQQMTIRNNVLDKIITVFRRHGA 179 ++EEV+KLL LKAQL D QKF LKTPKGTRDY+P+QM +R V D II F+RHGA Sbjct: 31 IEEEVAKLLKLKAQL-GPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGA 89 Query: 180 ECIDTPVFELKD 191 E IDTPVFELK+ Sbjct: 90 EVIDTPVFELKE 101 >BC080514-1|AAH80514.1| 509|Homo sapiens histidyl-tRNA synthetase protein. Length = 509 Score = 212 bits (517), Expect = 3e-54 Identities = 99/166 (59%), Positives = 120/166 (72%) Query: 191 DFDIAGIYDPMVPDAECLKVVTEILEALDIGQYILKVNHRRLLDGMFEACGVPADKFRTT 250 DFDIAG +DPM+PDAECLK++ EIL +L IG +++KVN RR+LDGMF CGV KFRT Sbjct: 175 DFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTI 234 Query: 251 CSTVDKLDKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXXXXXXA 310 CS+VDKLDK WEEV+ EM+ EKG++P+ ADRIG+Y + +G Sbjct: 235 CSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQ 294 Query: 311 ALEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAVL 356 ALEG+ +K L +Y LFGI DKI FDLSLARGLDYYTGVIYEAVL Sbjct: 295 ALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVL 340 Score = 158 bits (383), Expect = 5e-38 Identities = 73/120 (60%), Positives = 97/120 (80%) Query: 359 VSIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQS 418 +SIGVERIFS++E +L A + +RT++ V VASAQK LEER+K+ +ELWDAGIK E Sbjct: 382 LSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELL 441 Query: 419 YKKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKR 478 YKKNPK+LNQLQ+CEE IPL ++G+ ELK GV+K+R++T+REE +V R DLV+EIK+R Sbjct: 442 YKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRR 501 Score = 99 bits (238), Expect = 2e-20 Identities = 48/72 (66%), Positives = 56/72 (77%), Gaps = 1/72 (1%) Query: 120 VKEEVSKLLALKAQLVTEDAGPQKFTLKTPKGTRDYNPQQMTIRNNVLDKIITVFRRHGA 179 ++EEV+KLL LKAQL D QKF LKTPKGTRDY+P+QM +R V D II F+RHGA Sbjct: 31 IEEEVAKLLKLKAQL-GPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGA 89 Query: 180 ECIDTPVFELKD 191 E IDTPVFELK+ Sbjct: 90 EVIDTPVFELKE 101 >BC011807-1|AAH11807.1| 509|Homo sapiens histidyl-tRNA synthetase protein. Length = 509 Score = 212 bits (517), Expect = 3e-54 Identities = 99/166 (59%), Positives = 120/166 (72%) Query: 191 DFDIAGIYDPMVPDAECLKVVTEILEALDIGQYILKVNHRRLLDGMFEACGVPADKFRTT 250 DFDIAG +DPM+PDAECLK++ EIL +L IG +++KVN RR+LDGMF CGV KFRT Sbjct: 175 DFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTI 234 Query: 251 CSTVDKLDKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXXXXXXA 310 CS+VDKLDK WEEV+ EM+ EKG++P+ ADRIG+Y + +G Sbjct: 235 CSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQ 294 Query: 311 ALEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAVL 356 ALEG+ +K L +Y LFGI DKI FDLSLARGLDYYTGVIYEAVL Sbjct: 295 ALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVL 340 Score = 158 bits (383), Expect = 5e-38 Identities = 73/120 (60%), Positives = 97/120 (80%) Query: 359 VSIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQS 418 +SIGVERIFS++E +L A + +RT++ V VASAQK LEER+K+ +ELWDAGIK E Sbjct: 382 LSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELL 441 Query: 419 YKKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKR 478 YKKNPK+LNQLQ+CEE IPL ++G+ ELK GV+K+R++T+REE +V R DLV+EIK+R Sbjct: 442 YKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRR 501 Score = 99 bits (238), Expect = 2e-20 Identities = 48/72 (66%), Positives = 56/72 (77%), Gaps = 1/72 (1%) Query: 120 VKEEVSKLLALKAQLVTEDAGPQKFTLKTPKGTRDYNPQQMTIRNNVLDKIITVFRRHGA 179 ++EEV+KLL LKAQL D QKF LKTPKGTRDY+P+QM +R V D II F+RHGA Sbjct: 31 IEEEVAKLLKLKAQL-GPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGA 89 Query: 180 ECIDTPVFELKD 191 E IDTPVFELK+ Sbjct: 90 EVIDTPVFELKE 101 >X05345-1|CAA28956.1| 508|Homo sapiens protein ( Human mRNA for histidyl-tRNA synthetase (HRS). ). Length = 508 Score = 209 bits (510), Expect = 2e-53 Identities = 99/166 (59%), Positives = 119/166 (71%) Query: 191 DFDIAGIYDPMVPDAECLKVVTEILEALDIGQYILKVNHRRLLDGMFEACGVPADKFRTT 250 DFDIAG +DPM PDAE LK++ EIL +L IG +++KVN RR+LDGMF CGVP KFRT Sbjct: 175 DFDIAGQFDPMNPDAESLKIMCEILSSLQIGNFLVKVNDRRILDGMFAVCGVPDSKFRTI 234 Query: 251 CSTVDKLDKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXXXXXXA 310 CS+VDKLDK WEEV+ EM+ EKG++P+ ADRIG+Y + +G Sbjct: 235 CSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLVQDPKLSQNKQ 294 Query: 311 ALEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAVL 356 ALEG+ +K L +Y LFGI DKI FDLSLARGLDYYTGVIYEAVL Sbjct: 295 ALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVL 340 Score = 137 bits (332), Expect = 7e-32 Identities = 63/114 (55%), Positives = 85/114 (74%) Query: 365 RIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQSYKKNPK 424 RIFS++E +L A + +RT++ V VASAQK + K C LWDAGIK E YKKNPK Sbjct: 387 RIFSIVEQRLEALEEKIRTTETQVLVASAQKKLARGKTKACLRLWDAGIKAELLYKKNPK 446 Query: 425 MLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKR 478 +LNQLQ+CEE IPL ++G+ ELK GV+K+R++T+REE +V R +LV+EIK+R Sbjct: 447 LLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREELVEEIKRR 500 Score = 99 bits (238), Expect = 2e-20 Identities = 48/72 (66%), Positives = 56/72 (77%), Gaps = 1/72 (1%) Query: 120 VKEEVSKLLALKAQLVTEDAGPQKFTLKTPKGTRDYNPQQMTIRNNVLDKIITVFRRHGA 179 ++EEV+KLL LKAQL D QKF LKTPKGTRDY+P+QM +R V D II F+RHGA Sbjct: 31 IEEEVAKLLKLKAQL-GPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGA 89 Query: 180 ECIDTPVFELKD 191 E IDTPVFELK+ Sbjct: 90 EVIDTPVFELKE 101 >U18937-1|AAA73974.1| 506|Homo sapiens histidyl-tRNA synthetase homologue protein. Length = 506 Score = 207 bits (505), Expect = 8e-53 Identities = 94/166 (56%), Positives = 119/166 (71%) Query: 191 DFDIAGIYDPMVPDAECLKVVTEILEALDIGQYILKVNHRRLLDGMFEACGVPADKFRTT 250 DFDIAG +DPM+PDAECLK++ EIL L +G +++KVN RR++DGMF CGVP KFR Sbjct: 176 DFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAI 235 Query: 251 CSTVDKLDKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXXXXXXA 310 CS++DKLDK W++VR EM+ +KG++P+ ADRIG+Y + +G Sbjct: 236 CSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQ 295 Query: 311 ALEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAVL 356 ALEG+ +K L +Y LFGI DKI FDLSLARGLDYYTGVIYEAVL Sbjct: 296 ALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVL 341 Score = 144 bits (348), Expect = 8e-34 Identities = 64/121 (52%), Positives = 90/121 (74%) Query: 359 VSIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQS 418 +SIGVERIF ++E ++ VRT++ V+VA+ QKNFL+ER+K+ AELWD+GIK E Sbjct: 383 LSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEML 442 Query: 419 YKKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKR 478 YK NPK+L QL +CE IPL V++G+ ELK GV+KIR++ +REE + R + V EI+KR Sbjct: 443 YKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKR 502 Query: 479 I 479 + Sbjct: 503 L 503 Score = 72.9 bits (171), Expect = 2e-12 Identities = 37/75 (49%), Positives = 49/75 (65%), Gaps = 6/75 (8%) Query: 117 ESQVKEEVSKLLALKAQLVTEDAGPQKFTLKTPKGTRDYNPQQMTIRNNVLDKIITVFRR 176 +SQV E V L +QL P F +KTPKGTRD +PQ M +R +LD +I+ F+R Sbjct: 34 QSQVAEAV-----LTSQLKAHQEKPN-FIIKTPKGTRDLSPQHMVVREKILDLVISCFKR 87 Query: 177 HGAECIDTPVFELKD 191 HGA+ +DTP FELK+ Sbjct: 88 HGAKGMDTPAFELKE 102 >BC014982-1|AAH14982.1| 506|Homo sapiens histidyl-tRNA synthetase 2, mitochondrial (putative) protein. Length = 506 Score = 207 bits (505), Expect = 8e-53 Identities = 94/166 (56%), Positives = 119/166 (71%) Query: 191 DFDIAGIYDPMVPDAECLKVVTEILEALDIGQYILKVNHRRLLDGMFEACGVPADKFRTT 250 DFDIAG +DPM+PDAECLK++ EIL L +G +++KVN RR++DGMF CGVP KFR Sbjct: 176 DFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAI 235 Query: 251 CSTVDKLDKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXXXXXXA 310 CS++DKLDK W++VR EM+ +KG++P+ ADRIG+Y + +G Sbjct: 236 CSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQ 295 Query: 311 ALEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAVL 356 ALEG+ +K L +Y LFGI DKI FDLSLARGLDYYTGVIYEAVL Sbjct: 296 ALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVL 341 Score = 144 bits (348), Expect = 8e-34 Identities = 64/121 (52%), Positives = 90/121 (74%) Query: 359 VSIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQS 418 +SIGVERIF ++E ++ VRT++ V+VA+ QKNFL+ER+K+ AELWD+GIK E Sbjct: 383 LSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEML 442 Query: 419 YKKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKR 478 YK NPK+L QL +CE IPL V++G+ ELK GV+KIR++ +REE + R + V EI+KR Sbjct: 443 YKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKR 502 Query: 479 I 479 + Sbjct: 503 L 503 Score = 72.9 bits (171), Expect = 2e-12 Identities = 37/75 (49%), Positives = 49/75 (65%), Gaps = 6/75 (8%) Query: 117 ESQVKEEVSKLLALKAQLVTEDAGPQKFTLKTPKGTRDYNPQQMTIRNNVLDKIITVFRR 176 +SQV E V L +QL P F +KTPKGTRD +PQ M +R +LD +I+ F+R Sbjct: 34 QSQVAEAV-----LTSQLKAHQEKPN-FIIKTPKGTRDLSPQHMVVREKILDLVISCFKR 87 Query: 177 HGAECIDTPVFELKD 191 HGA+ +DTP FELK+ Sbjct: 88 HGAKGMDTPAFELKE 102 >BC007680-1|AAH07680.1| 506|Homo sapiens histidyl-tRNA synthetase 2, mitochondrial (putative) protein. Length = 506 Score = 207 bits (505), Expect = 8e-53 Identities = 94/166 (56%), Positives = 119/166 (71%) Query: 191 DFDIAGIYDPMVPDAECLKVVTEILEALDIGQYILKVNHRRLLDGMFEACGVPADKFRTT 250 DFDIAG +DPM+PDAECLK++ EIL L +G +++KVN RR++DGMF CGVP KFR Sbjct: 176 DFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAI 235 Query: 251 CSTVDKLDKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXXXXXXA 310 CS++DKLDK W++VR EM+ +KG++P+ ADRIG+Y + +G Sbjct: 236 CSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQ 295 Query: 311 ALEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAVL 356 ALEG+ +K L +Y LFGI DKI FDLSLARGLDYYTGVIYEAVL Sbjct: 296 ALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVL 341 Score = 144 bits (348), Expect = 8e-34 Identities = 64/121 (52%), Positives = 90/121 (74%) Query: 359 VSIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQS 418 +SIGVERIF ++E ++ VRT++ V+VA+ QKNFL+ER+K+ AELWD+GIK E Sbjct: 383 LSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEML 442 Query: 419 YKKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKR 478 YK NPK+L QL +CE IPL V++G+ ELK GV+KIR++ +REE + R + V EI+KR Sbjct: 443 YKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKR 502 Query: 479 I 479 + Sbjct: 503 L 503 Score = 72.9 bits (171), Expect = 2e-12 Identities = 37/75 (49%), Positives = 49/75 (65%), Gaps = 6/75 (8%) Query: 117 ESQVKEEVSKLLALKAQLVTEDAGPQKFTLKTPKGTRDYNPQQMTIRNNVLDKIITVFRR 176 +SQV E V L +QL P F +KTPKGTRD +PQ M +R +LD +I+ F+R Sbjct: 34 QSQVAEAV-----LTSQLKAHQEKPN-FIIKTPKGTRDLSPQHMVVREKILDLVISCFKR 87 Query: 177 HGAECIDTPVFELKD 191 HGA+ +DTP FELK+ Sbjct: 88 HGAKGMDTPAFELKE 102 >X60656-1|CAA43063.1| 225|Homo sapiens elongation factor 1-beta protein. Length = 225 Score = 46.0 bits (104), Expect = 3e-04 Identities = 22/63 (34%), Positives = 38/63 (60%) Query: 36 KEVYNFEEIDKHLSHYSYICGYVPSKPDVDVAKALKSLDFSNYKYIKRWWNHMRSFSDTE 95 K + ++ +L+ SYI GYVPS+ DV V +A+ S ++ + RW+NH++S+ + Sbjct: 7 KSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEK 66 Query: 96 VSL 98 SL Sbjct: 67 ASL 69 >X60489-1|CAA43019.1| 225|Homo sapiens elongation factor-1-beta protein. Length = 225 Score = 46.0 bits (104), Expect = 3e-04 Identities = 22/63 (34%), Positives = 38/63 (60%) Query: 36 KEVYNFEEIDKHLSHYSYICGYVPSKPDVDVAKALKSLDFSNYKYIKRWWNHMRSFSDTE 95 K + ++ +L+ SYI GYVPS+ DV V +A+ S ++ + RW+NH++S+ + Sbjct: 7 KSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEK 66 Query: 96 VSL 98 SL Sbjct: 67 ASL 69 >CR456825-1|CAG33106.1| 225|Homo sapiens EEF1B2 protein. Length = 225 Score = 46.0 bits (104), Expect = 3e-04 Identities = 22/63 (34%), Positives = 38/63 (60%) Query: 36 KEVYNFEEIDKHLSHYSYICGYVPSKPDVDVAKALKSLDFSNYKYIKRWWNHMRSFSDTE 95 K + ++ +L+ SYI GYVPS+ DV V +A+ S ++ + RW+NH++S+ + Sbjct: 7 KSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEK 66 Query: 96 VSL 98 SL Sbjct: 67 ASL 69 >BT007079-1|AAP35742.1| 225|Homo sapiens eukaryotic translation elongation factor 1 beta 2 protein. Length = 225 Score = 46.0 bits (104), Expect = 3e-04 Identities = 22/63 (34%), Positives = 38/63 (60%) Query: 36 KEVYNFEEIDKHLSHYSYICGYVPSKPDVDVAKALKSLDFSNYKYIKRWWNHMRSFSDTE 95 K + ++ +L+ SYI GYVPS+ DV V +A+ S ++ + RW+NH++S+ + Sbjct: 7 KSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEK 66 Query: 96 VSL 98 SL Sbjct: 67 ASL 69 >BC067787-1|AAH67787.1| 225|Homo sapiens eukaryotic translation elongation factor 1 beta 2 protein. Length = 225 Score = 46.0 bits (104), Expect = 3e-04 Identities = 22/63 (34%), Positives = 38/63 (60%) Query: 36 KEVYNFEEIDKHLSHYSYICGYVPSKPDVDVAKALKSLDFSNYKYIKRWWNHMRSFSDTE 95 K + ++ +L+ SYI GYVPS+ DV V +A+ S ++ + RW+NH++S+ + Sbjct: 7 KSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEK 66 Query: 96 VSL 98 SL Sbjct: 67 ASL 69 >BC004931-1|AAH04931.1| 225|Homo sapiens eukaryotic translation elongation factor 1 beta 2 protein. Length = 225 Score = 46.0 bits (104), Expect = 3e-04 Identities = 22/63 (34%), Positives = 38/63 (60%) Query: 36 KEVYNFEEIDKHLSHYSYICGYVPSKPDVDVAKALKSLDFSNYKYIKRWWNHMRSFSDTE 95 K + ++ +L+ SYI GYVPS+ DV V +A+ S ++ + RW+NH++S+ + Sbjct: 7 KSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEK 66 Query: 96 VSL 98 SL Sbjct: 67 ASL 69 >BC000211-1|AAH00211.1| 225|Homo sapiens eukaryotic translation elongation factor 1 beta 2 protein. Length = 225 Score = 46.0 bits (104), Expect = 3e-04 Identities = 22/63 (34%), Positives = 38/63 (60%) Query: 36 KEVYNFEEIDKHLSHYSYICGYVPSKPDVDVAKALKSLDFSNYKYIKRWWNHMRSFSDTE 95 K + ++ +L+ SYI GYVPS+ DV V +A+ S ++ + RW+NH++S+ + Sbjct: 7 KSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEK 66 Query: 96 VSL 98 SL Sbjct: 67 ASL 69 >AC007383-2|AAY15062.1| 225|Homo sapiens unknown protein. Length = 225 Score = 46.0 bits (104), Expect = 3e-04 Identities = 22/63 (34%), Positives = 38/63 (60%) Query: 36 KEVYNFEEIDKHLSHYSYICGYVPSKPDVDVAKALKSLDFSNYKYIKRWWNHMRSFSDTE 95 K + ++ +L+ SYI GYVPS+ DV V +A+ S ++ + RW+NH++S+ + Sbjct: 7 KSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSSPPPADLCHALRWYNHIKSYEKEK 66 Query: 96 VSL 98 SL Sbjct: 67 ASL 69 >BC009350-1|AAH09350.2| 829|Homo sapiens EIF2AK4 protein protein. Length = 829 Score = 42.7 bits (96), Expect = 0.003 Identities = 28/130 (21%), Positives = 54/130 (41%) Query: 360 SIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQSY 419 +IGV + A + + +V S D+ V S + + + + +LW AGI E Y Sbjct: 551 AIGVSIAIDKISAAVLNMEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMY 610 Query: 420 KKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKRI 479 + ++C ++I ++ D E VK + E V +LV + +++ Sbjct: 611 DWSQSQEELQEYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKL 670 Query: 480 DNLNLNQLNG 489 ++ NG Sbjct: 671 RTKVTDERNG 680 Score = 35.1 bits (77), Expect = 0.57 Identities = 38/173 (21%), Positives = 73/173 (42%), Gaps = 10/173 (5%) Query: 192 FDIA-GIYDPMVPDAECLKVVTEILE---ALDIGQYILKVNHRRLLDGMFEACGVPADKF 247 FDI + +P AE + + EI++ AL Y + +NH LL + CG+P DK Sbjct: 341 FDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKL 400 Query: 248 -RTTCSTVDKL-DKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXX 305 + D + +K EV + N +S ++ R+ ++ G Sbjct: 401 SQVYIILYDAVTEKLTRREVEAKFCN-LSLSSNSLCRLYKFIEQKGDLQDLMPTINSLIK 459 Query: 306 XXXXAA---LEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAV 355 A G++ ++ ++ + IK ++L +L L + + G+I++ V Sbjct: 460 QKTGIAQLVKYGLKDLEEVVGLLKKLCIKLQVLINLGLVYKVQQHNGIIFQFV 512 >AL157497-1|CAB75678.1| 938|Homo sapiens hypothetical protein protein. Length = 938 Score = 42.7 bits (96), Expect = 0.003 Identities = 28/130 (21%), Positives = 54/130 (41%) Query: 360 SIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQSY 419 +IGV + A + + +V S D+ V S + + + + +LW AGI E Y Sbjct: 660 AIGVSIAIDKISAAVLNMEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMY 719 Query: 420 KKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKRI 479 + ++C ++I ++ D E VK + E V +LV + +++ Sbjct: 720 DWSQSQEELQEYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKL 779 Query: 480 DNLNLNQLNG 489 ++ NG Sbjct: 780 RTKVTDERNG 789 Score = 38.7 bits (86), Expect = 0.046 Identities = 39/173 (22%), Positives = 74/173 (42%), Gaps = 10/173 (5%) Query: 192 FDIA-GIYDPMVPDAECLKVVTEILE---ALDIGQYILKVNHRRLLDGMFEACGVPADKF 247 FDI + +P AE + + EI++ AL Y + +NH LL + CG+P DK Sbjct: 450 FDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKL 509 Query: 248 -RTTCSTVDKL-DKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXX 305 + D + +K EV + N +S ++ R+ ++ G Sbjct: 510 SQVYIILYDAVTEKLTRREVEAKFCN-LSLSSNSLCRLYKFIEQKGDLQDLMPTINSLIK 568 Query: 306 XXXXAA---LEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAV 355 A G++ ++ ++ + GIK ++L +L L + + G+I++ V Sbjct: 569 QKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLGLVYKVQQHNGIIFQFV 621 >AK027011-1|BAB15625.1| 806|Homo sapiens protein ( Homo sapiens cDNA: FLJ23358 fis, clone HEP14996. ). Length = 806 Score = 42.7 bits (96), Expect = 0.003 Identities = 28/130 (21%), Positives = 54/130 (41%) Query: 360 SIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQSY 419 +IGV + A + + +V S D+ V S + + + + +LW AGI E Y Sbjct: 528 AIGVSIAIDKISAAVLNMEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMY 587 Query: 420 KKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKRI 479 + ++C ++I ++ D E VK + E V +LV + +++ Sbjct: 588 DWSQSQEELQEYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKL 647 Query: 480 DNLNLNQLNG 489 ++ NG Sbjct: 648 RTKVTDERNG 657 Score = 38.7 bits (86), Expect = 0.046 Identities = 39/173 (22%), Positives = 74/173 (42%), Gaps = 10/173 (5%) Query: 192 FDIA-GIYDPMVPDAECLKVVTEILE---ALDIGQYILKVNHRRLLDGMFEACGVPADKF 247 FDI + +P AE + + EI++ AL Y + +NH LL + CG+P DK Sbjct: 318 FDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKL 377 Query: 248 -RTTCSTVDKL-DKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXX 305 + D + +K EV + N +S ++ R+ ++ G Sbjct: 378 SQVYIILYDAVTEKLTRREVEAKFCN-LSLSSNSLCRLYKFIEQKGDLQDLMPTINSLIK 436 Query: 306 XXXXAA---LEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAV 355 A G++ ++ ++ + GIK ++L +L L + + G+I++ V Sbjct: 437 QKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLGLVYKVQQHNGIIFQFV 489 >AJ243428-1|CAB58360.1| 548|Homo sapiens putative eIF2 alpha kinase protein. Length = 548 Score = 42.7 bits (96), Expect = 0.003 Identities = 28/130 (21%), Positives = 54/130 (41%) Query: 360 SIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQSY 419 +IGV + A + + +V S D+ V S + + + + +LW AGI E Y Sbjct: 270 AIGVSIAIDKISAAVLNMEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMY 329 Query: 420 KKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKRI 479 + ++C ++I ++ D E VK + E V +LV + +++ Sbjct: 330 DWSQSQEELQEYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKL 389 Query: 480 DNLNLNQLNG 489 ++ NG Sbjct: 390 RTKVTDERNG 399 Score = 38.7 bits (86), Expect = 0.046 Identities = 39/173 (22%), Positives = 74/173 (42%), Gaps = 10/173 (5%) Query: 192 FDIA-GIYDPMVPDAECLKVVTEILE---ALDIGQYILKVNHRRLLDGMFEACGVPADKF 247 FDI + +P AE + + EI++ AL Y + +NH LL + CG+P DK Sbjct: 60 FDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKL 119 Query: 248 -RTTCSTVDKL-DKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXX 305 + D + +K EV + N +S ++ R+ ++ G Sbjct: 120 SQVYIILYDAVTEKLTRREVEAKFCN-LSLSSNSLCRLYKFIEQKGDLQDLMPTINSLIK 178 Query: 306 XXXXAA---LEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAV 355 A G++ ++ ++ + GIK ++L +L L + + G+I++ V Sbjct: 179 QKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLGLVYKVQQHNGIIFQFV 231 >AB037759-1|BAA92576.1| 1495|Homo sapiens KIAA1338 protein protein. Length = 1495 Score = 42.7 bits (96), Expect = 0.003 Identities = 28/130 (21%), Positives = 54/130 (41%) Query: 360 SIGVERIFSVLEAKLAAGDITVRTSDIDVYVASAQKNFLEERMKICAELWDAGIKTEQSY 419 +IGV + A + + +V S D+ V S + + + + +LW AGI E Y Sbjct: 1217 AIGVSIAIDKISAAVLNMEESVTISSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMY 1276 Query: 420 KKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVKIRNITTREEDEVPRNDLVQEIKKRI 479 + ++C ++I ++ D E VK + E V +LV + +++ Sbjct: 1277 DWSQSQEELQEYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLETELVDHVLQKL 1336 Query: 480 DNLNLNQLNG 489 ++ NG Sbjct: 1337 RTKVTDERNG 1346 Score = 38.7 bits (86), Expect = 0.046 Identities = 39/173 (22%), Positives = 74/173 (42%), Gaps = 10/173 (5%) Query: 192 FDIA-GIYDPMVPDAECLKVVTEILE---ALDIGQYILKVNHRRLLDGMFEACGVPADKF 247 FDI + +P AE + + EI++ AL Y + +NH LL + CG+P DK Sbjct: 1007 FDIVTSTTNSFLPTAEIIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKL 1066 Query: 248 -RTTCSTVDKL-DKSPWEEVRTEMINEKGVSPDAADRIGEYGRLNGSTXXXXXXXXXXXX 305 + D + +K EV + N +S ++ R+ ++ G Sbjct: 1067 SQVYIILYDAVTEKLTRREVEAKFCN-LSLSSNSLCRLYKFIEQKGDLQDLMPTINSLIK 1125 Query: 306 XXXXAA---LEGVEAIKTLLQYCELFGIKDKILFDLSLARGLDYYTGVIYEAV 355 A G++ ++ ++ + GIK ++L +L L + + G+I++ V Sbjct: 1126 QKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLINLGLVYKVQQHNGIIFQFV 1178 >AK125242-1|BAC86097.1| 307|Homo sapiens protein ( Homo sapiens cDNA FLJ43252 fis, clone HEART2006909. ). Length = 307 Score = 32.3 bits (70), Expect = 4.0 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 2/91 (2%) Query: 395 KNFLEERMKICAELWDAGIKTEQSYKKNPKMLNQLQHCEENKIPLAVVLGDSELKRGVVK 454 K+ L K + W + I+ + K+ + L+ +ENK+ +A+V+ + G+V Sbjct: 139 KDLLPHLEKPVSFRWQSLIRPPYFVPETKKIDDLLREFQENKVHIAIVVDEFGGTSGIVT 198 Query: 455 IRNITTREEDEVPRNDLVQEIKKRIDNLNLN 485 + +I E+ ND E +K LN N Sbjct: 199 LEDILEEIVGEI--NDEYDEEEKFYSKLNYN 227 Database: human Posted date: Oct 5, 2007 11:13 AM Number of letters in database: 73,234,838 Number of sequences in database: 224,733 Lambda K H 0.318 0.136 0.389 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 62,825,967 Number of Sequences: 224733 Number of extensions: 2426638 Number of successful extensions: 5529 Number of sequences better than 10.0: 22 Number of HSP's better than 10.0 without gapping: 21 Number of HSP's successfully gapped in prelim test: 1 Number of HSP's that attempted gapping in prelim test: 5467 Number of HSP's gapped (non-prelim): 51 length of query: 491 length of database: 73,234,838 effective HSP length: 93 effective length of query: 398 effective length of database: 52,334,669 effective search space: 20829198262 effective search space used: 20829198262 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits) S2: 67 (31.1 bits)
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