Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000983-TA|BGIBMGA000983-PA|IPR002290|Serine/threonine
protein kinase, IPR008271|Serine/threonine protein kinase, active
site, IPR003280|K+ channel, two pore, IPR000719|Protein kinase,
IPR011009|Protein kinase-like, IPR013099|Ion transport 2
(559 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VYY5 Cluster: CG1756-PA; n=7; Endopterygota|Rep: CG17... 357 6e-97
UniRef50_P22612 Cluster: cAMP-dependent protein kinase, gamma-ca... 249 2e-64
UniRef50_P17612 Cluster: cAMP-dependent protein kinase, alpha-ca... 248 4e-64
UniRef50_Q17JG1 Cluster: Camp-dependent protein kinase catalytic... 229 2e-58
UniRef50_Q4E4S9 Cluster: Protein kinase A catalytic subunit isof... 217 5e-55
UniRef50_Q8J0I6 Cluster: CAMP-dependent protein kinase A catalyt... 213 1e-53
UniRef50_P51817 Cluster: Serine/threonine-protein kinase PRKX; n... 210 6e-53
UniRef50_Q33DX4 Cluster: Putative cyclic AMP-dependent protein k... 210 1e-52
UniRef50_O13367 Cluster: CAMP-dependent protein kinase catalytic... 210 1e-52
UniRef50_Q8NIL1 Cluster: CAMP-dependent protein kinase catalytic... 209 1e-52
UniRef50_UPI000155CDCE Cluster: PREDICTED: similar to protein ki... 209 2e-52
UniRef50_P34099 Cluster: cAMP-dependent protein kinase catalytic... 208 3e-52
UniRef50_O44020 Cluster: PKA protein; n=13; Eukaryota|Rep: PKA p... 207 5e-52
UniRef50_Q9BMY6 Cluster: CAMP-dependent protein kinase catalytic... 202 1e-50
UniRef50_Q4UE84 Cluster: CAMP-dependent protein kinase catalytic... 200 6e-50
UniRef50_P40376 Cluster: cAMP-dependent protein kinase catalytic... 197 7e-49
UniRef50_Q9VA47 Cluster: CG12069-PA; n=3; Sophophora|Rep: CG1206... 196 1e-48
UniRef50_Q4SLK1 Cluster: Chromosome 15 SCAF14556, whole genome s... 195 3e-48
UniRef50_P05986 Cluster: cAMP-dependent protein kinase type 3; n... 193 1e-47
UniRef50_Q20541 Cluster: Cyclic AMP-dependent protein kinase, ca... 192 2e-47
UniRef50_A6QTK8 Cluster: Serine/threonine-protein kinase PRKX; n... 191 5e-47
UniRef50_Q6CW38 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 190 8e-47
UniRef50_Q2U6J7 Cluster: CAMP-dependent protein kinase catalytic... 190 8e-47
UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome s... 189 1e-46
UniRef50_UPI00006CB393 Cluster: Protein kinase domain containing... 188 3e-46
UniRef50_Q22DD1 Cluster: Protein kinase domain containing protei... 188 3e-46
UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23; ... 185 2e-45
UniRef50_P21901 Cluster: Spermatozoon-associated protein kinase;... 185 2e-45
UniRef50_Q17941 Cluster: Serine/threonine-protein kinase akt-1; ... 184 7e-45
UniRef50_Q33DX3 Cluster: Putative cyclic AMP-dependent protein k... 182 2e-44
UniRef50_Q4N4B2 Cluster: CAMP-dependent protein kinase catalytic... 181 5e-44
UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate pro... 180 7e-44
UniRef50_A7AWS2 Cluster: cAMP-dependent protein kinase; n=1; Bab... 179 2e-43
UniRef50_Q86ZN6 Cluster: CAMP-dependent protein kinase catalytic... 179 2e-43
UniRef50_P16911 Cluster: Protein kinase DC1; n=5; Sophophora|Rep... 178 3e-43
UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome s... 177 6e-43
UniRef50_Q2PJ68 Cluster: Putative uncharacterized protein sgk-1;... 177 8e-43
UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta i... 177 8e-43
UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=... 176 1e-42
UniRef50_A0CMB4 Cluster: Chromosome undetermined scaffold_21, wh... 175 2e-42
UniRef50_P28178 Cluster: Protein kinase 2; n=2; Dictyostelium di... 175 2e-42
UniRef50_Q9P7J8 Cluster: Serine/threonine-protein kinase gad8; n... 174 4e-42
UniRef50_A0BEY5 Cluster: Chromosome undetermined scaffold_103, w... 173 8e-42
UniRef50_P12688 Cluster: Serine/threonine-protein kinase YPK1; n... 173 1e-41
UniRef50_UPI000150A8F4 Cluster: Protein kinase domain containing... 172 2e-41
UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform... 170 1e-40
UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1; Chl... 169 2e-40
UniRef50_A0E7B2 Cluster: Chromosome undetermined scaffold_80, wh... 169 2e-40
UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme ... 169 2e-40
UniRef50_A5DTG0 Cluster: Serine/threonine-protein kinase YPK1; n... 168 3e-40
UniRef50_P11792 Cluster: Serine/threonine-protein kinase SCH9; n... 168 4e-40
UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14; Ap... 167 5e-40
UniRef50_Q240P0 Cluster: Protein kinase domain containing protei... 167 5e-40
UniRef50_P54644 Cluster: RAC family serine/threonine-protein kin... 167 7e-40
UniRef50_O96997 Cluster: Protein kinase C; n=2; Tetractinomorpha... 167 9e-40
UniRef50_A0CDF0 Cluster: Chromosome undetermined scaffold_17, wh... 167 9e-40
UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to cGMP-depen... 166 1e-39
UniRef50_Q231C9 Cluster: Protein kinase C terminal domain contai... 166 2e-39
UniRef50_Q6CD34 Cluster: Yarrowia lipolytica chromosome C of str... 165 2e-39
UniRef50_UPI00006CB3D2 Cluster: Protein kinase domain containing... 165 4e-39
UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5; ... 165 4e-39
UniRef50_UPI000049A5C0 Cluster: protein kinase; n=1; Entamoeba h... 164 5e-39
UniRef50_A6RHI7 Cluster: Serine/threonine-protein kinase Sgk2; n... 164 5e-39
UniRef50_Q6PLK2 Cluster: Protein kinase B-like protein; n=4; Pla... 164 6e-39
UniRef50_A2F9U6 Cluster: AGC family protein kinase; n=1; Trichom... 164 6e-39
UniRef50_A2DV83 Cluster: AGC family protein kinase; n=1; Trichom... 163 8e-39
UniRef50_Q2U061 Cluster: Ribosomal protein S6 kinase and related... 163 1e-38
UniRef50_Q54IF2 Cluster: Putative uncharacterized protein; n=1; ... 162 2e-38
UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2; End... 162 2e-38
UniRef50_Q5K7C2 Cluster: Protein kinase Sch9, putative; n=4; Aga... 162 2e-38
UniRef50_Q24DD1 Cluster: Protein kinase domain containing protei... 162 3e-38
UniRef50_Q26334 Cluster: Serine/threonine protein kinase; n=2; E... 161 3e-38
UniRef50_A0E058 Cluster: Chromosome undetermined scaffold_71, wh... 161 3e-38
UniRef50_Q9FXQ0 Cluster: Cyclic nucreotide dependent protein kin... 161 6e-38
UniRef50_Q5CWD4 Cluster: Cyclic nucleotide (CGMP)-dependent prot... 161 6e-38
UniRef50_A0BY36 Cluster: Chromosome undetermined scaffold_136, w... 161 6e-38
UniRef50_UPI00006CB772 Cluster: Protein kinase domain containing... 160 8e-38
UniRef50_A0E8L1 Cluster: Chromosome undetermined scaffold_83, wh... 160 8e-38
UniRef50_A0CFD9 Cluster: Chromosome undetermined scaffold_175, w... 160 1e-37
UniRef50_UPI00006CDDB0 Cluster: Protein kinase domain containing... 159 2e-37
UniRef50_Q4SYX7 Cluster: Chromosome 21 SCAF11909, whole genome s... 159 2e-37
UniRef50_Q24HP6 Cluster: Protein kinase domain containing protei... 159 2e-37
UniRef50_A2E5K8 Cluster: AGC family protein kinase; n=1; Trichom... 159 2e-37
UniRef50_A0DDH0 Cluster: Chromosome undetermined scaffold_46, wh... 159 2e-37
UniRef50_Q234E6 Cluster: Protein kinase domain containing protei... 159 2e-37
UniRef50_A7TPV4 Cluster: Putative uncharacterized protein; n=1; ... 158 3e-37
UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, wh... 158 4e-37
UniRef50_A2FLX7 Cluster: AGC family protein kinase; n=4; Trichom... 157 5e-37
UniRef50_A2ELF7 Cluster: AGC family protein kinase; n=4; Trichom... 157 5e-37
UniRef50_A0C512 Cluster: Chromosome undetermined scaffold_15, wh... 157 5e-37
UniRef50_Q8INB9 Cluster: RAC serine/threonine-protein kinase; n=... 157 7e-37
UniRef50_UPI000049878B Cluster: protein kinase; n=3; Entamoeba h... 157 1e-36
UniRef50_UPI00015A51B8 Cluster: Protein kinase C delta type (EC ... 157 1e-36
UniRef50_Q4XNV1 Cluster: Rac-beta serine/threonine protein kinas... 157 1e-36
UniRef50_A2DS63 Cluster: AGC family protein kinase; n=3; Trichom... 157 1e-36
UniRef50_A0DLX8 Cluster: Chromosome undetermined scaffold_56, wh... 157 1e-36
UniRef50_Q4RZQ9 Cluster: Chromosome 18 SCAF14786, whole genome s... 156 1e-36
UniRef50_O61225 Cluster: Serine/Threonine protein kinase; n=1; S... 156 1e-36
UniRef50_Q96BR1 Cluster: Serine/threonine-protein kinase Sgk3; n... 156 1e-36
UniRef50_Q4DL90 Cluster: Rac serine-threonine kinase, putative; ... 156 2e-36
UniRef50_Q6C936 Cluster: Yarrowia lipolytica chromosome D of str... 156 2e-36
UniRef50_Q9UBS0 Cluster: Ribosomal protein S6 kinase beta-2; n=6... 156 2e-36
UniRef50_P05129 Cluster: Protein kinase C gamma type; n=98; Eume... 155 2e-36
UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2; Eim... 155 3e-36
UniRef50_A2FIJ5 Cluster: AGC family protein kinase; n=1; Trichom... 155 3e-36
UniRef50_A7SL27 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 155 4e-36
UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|R... 154 5e-36
UniRef50_Q7R5X8 Cluster: GLP_81_97826_96747; n=2; Giardia intest... 154 5e-36
UniRef50_A0BD03 Cluster: Chromosome undetermined scaffold_10, wh... 154 5e-36
UniRef50_Q22HC2 Cluster: Protein kinase domain containing protei... 154 7e-36
UniRef50_Q21694 Cluster: Putative uncharacterized protein; n=2; ... 154 7e-36
UniRef50_O61224 Cluster: Serine/Threonine protein kinase; n=1; S... 154 7e-36
UniRef50_A0DTL3 Cluster: Chromosome undetermined scaffold_63, wh... 154 7e-36
UniRef50_Q4PH11 Cluster: Putative uncharacterized protein; n=1; ... 154 7e-36
UniRef50_A5DV85 Cluster: Serine/threonine-protein kinase SCH9; n... 154 7e-36
UniRef50_P31751 Cluster: RAC-beta serine/threonine-protein kinas... 154 7e-36
UniRef50_UPI00006CFFA7 Cluster: Protein kinase domain containing... 153 9e-36
UniRef50_A2E8U1 Cluster: AGC family protein kinase; n=1; Trichom... 153 9e-36
UniRef50_Q9HGS0 Cluster: CAMP-dependent protein kinase catalytic... 153 9e-36
UniRef50_P87253 Cluster: Protein kinase C-like; n=6; Pezizomycot... 153 9e-36
UniRef50_Q8SRK8 Cluster: Probable cAMP-dependent protein kinase ... 153 1e-35
UniRef50_A0CSN3 Cluster: Chromosome undetermined scaffold_26, wh... 153 2e-35
UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101, w... 153 2e-35
UniRef50_A2E8A4 Cluster: AGC family protein kinase; n=1; Trichom... 152 3e-35
UniRef50_A2E224 Cluster: AGC family protein kinase; n=1; Trichom... 152 3e-35
UniRef50_A0C5F6 Cluster: Chromosome undetermined scaffold_15, wh... 152 3e-35
UniRef50_A0BNJ0 Cluster: Chromosome undetermined scaffold_118, w... 152 3e-35
UniRef50_Q39030 Cluster: Serine/threonine-protein kinase AtPK19;... 152 3e-35
UniRef50_UPI00004999BB Cluster: protein kinase; n=3; Entamoeba h... 151 4e-35
UniRef50_Q9NAH6 Cluster: Putative uncharacterized protein rsks-1... 151 4e-35
UniRef50_Q2UNA7 Cluster: Ribosomal protein S6 kinase and related... 151 4e-35
UniRef50_UPI00006A0EC2 Cluster: UPI00006A0EC2 related cluster; n... 151 5e-35
UniRef50_A5K8X1 Cluster: Rac-beta serine/threonine protein kinas... 151 5e-35
UniRef50_Q59EH6 Cluster: 3-phosphoinositide dependent protein ki... 151 5e-35
UniRef50_Q6C292 Cluster: Similar to sp|P24583 Saccharomyces cere... 151 5e-35
UniRef50_O15530 Cluster: 3-phosphoinositide-dependent protein ki... 151 5e-35
UniRef50_P90980 Cluster: Protein kinase C-like 2; n=49; Eumetazo... 151 5e-35
UniRef50_UPI00015B57E6 Cluster: PREDICTED: similar to protein ki... 151 6e-35
UniRef50_Q8MYF1 Cluster: Similar to Dictyostelium discoideum (Sl... 151 6e-35
UniRef50_A2FDD2 Cluster: AGC family protein kinase; n=2; Trichom... 151 6e-35
UniRef50_A2DP41 Cluster: AGC family protein kinase; n=1; Trichom... 151 6e-35
UniRef50_P50530 Cluster: Serine/threonine-protein kinase sck1; n... 151 6e-35
UniRef50_A0EFE8 Cluster: Chromosome undetermined scaffold_93, wh... 150 8e-35
UniRef50_Q4T638 Cluster: Chromosome undetermined SCAF8942, whole... 150 1e-34
UniRef50_Q23PX4 Cluster: Protein kinase domain containing protei... 150 1e-34
UniRef50_A2EEZ5 Cluster: AGC family protein kinase; n=2; Trichom... 150 1e-34
UniRef50_A0DCJ0 Cluster: Chromosome undetermined scaffold_45, wh... 150 1e-34
UniRef50_Q0UME1 Cluster: Putative uncharacterized protein; n=1; ... 150 1e-34
UniRef50_A1CR23 Cluster: CAMP-dependent protein kinase, putative... 150 1e-34
UniRef50_Q10364 Cluster: Serine/threonine-protein kinase sck2; n... 150 1e-34
UniRef50_P23443 Cluster: Ribosomal protein S6 kinase beta-1 (EC ... 150 1e-34
UniRef50_Q39908 Cluster: CAMP-dependent protein kinase; n=1; Gon... 149 1e-34
UniRef50_A1Z7T1 Cluster: CG2049-PC, isoform C; n=7; Fungi/Metazo... 149 1e-34
UniRef50_A0E8C9 Cluster: Chromosome undetermined scaffold_82, wh... 149 1e-34
UniRef50_A0DTA2 Cluster: Chromosome undetermined scaffold_62, wh... 149 1e-34
UniRef50_A0CUG4 Cluster: Chromosome undetermined scaffold_28, wh... 149 1e-34
UniRef50_A0CC53 Cluster: Chromosome undetermined scaffold_166, w... 149 1e-34
UniRef50_A0BJU7 Cluster: Chromosome undetermined scaffold_110, w... 149 1e-34
UniRef50_Q16513 Cluster: Serine/threonine-protein kinase N2; n=4... 149 1e-34
UniRef50_UPI000065F79D Cluster: Protein kinase C delta type (EC ... 149 2e-34
UniRef50_A2ECT2 Cluster: AGC family protein kinase; n=3; Trichom... 149 2e-34
UniRef50_Q02156 Cluster: Protein kinase C epsilon type; n=34; Co... 149 2e-34
UniRef50_A3KP71 Cluster: Prkcq protein; n=4; Clupeocephala|Rep: ... 149 3e-34
UniRef50_Q23NJ5 Cluster: Protein kinase domain containing protei... 149 3e-34
UniRef50_O42632 Cluster: Protein kinase C-like; n=14; Fungi|Rep:... 149 3e-34
UniRef50_Q4T021 Cluster: Chromosome undetermined SCAF11390, whol... 148 3e-34
UniRef50_A2BIH5 Cluster: Novel protein similar to vertebrate pro... 148 3e-34
UniRef50_Q5C2X7 Cluster: SJCHGC09382 protein; n=1; Schistosoma j... 148 3e-34
UniRef50_Q245J7 Cluster: Protein kinase domain containing protei... 148 3e-34
UniRef50_Q23DN8 Cluster: Cyclic nucleotide-binding domain contai... 148 3e-34
UniRef50_A2DW86 Cluster: AGC family protein kinase; n=1; Trichom... 148 3e-34
UniRef50_Q8TFJ3 Cluster: Protein kinase A catalytic subunit; n=1... 148 3e-34
UniRef50_Q05655 Cluster: Protein kinase C delta type; n=61; Eume... 148 3e-34
UniRef50_UPI00006CFF91 Cluster: Protein kinase domain containing... 148 4e-34
UniRef50_A7TL28 Cluster: Putative uncharacterized protein; n=1; ... 148 4e-34
UniRef50_Q16512 Cluster: Serine/threonine-protein kinase N1; n=2... 148 4e-34
UniRef50_Q4SG88 Cluster: Chromosome 17 SCAF14597, whole genome s... 147 6e-34
UniRef50_Q7QUE9 Cluster: GLP_59_15138_16382; n=2; Giardia intest... 147 6e-34
UniRef50_Q69G16 Cluster: Protein kinase C type beta; n=2; Bilate... 147 6e-34
UniRef50_A0DZB2 Cluster: Chromosome undetermined scaffold_7, who... 147 6e-34
UniRef50_Q1MX42 Cluster: Protein kinase C, delta V; n=9; Euteleo... 147 8e-34
UniRef50_Q8MUA6 Cluster: Protein kinase C-related kinase; n=1; H... 147 8e-34
UniRef50_Q22RI5 Cluster: Protein kinase domain containing protei... 147 8e-34
UniRef50_Q00078 Cluster: Protein kinase C-like; n=8; Eurotiomyce... 147 8e-34
UniRef50_Q91948 Cluster: PKN; n=3; Euteleostomi|Rep: PKN - Xenop... 146 1e-33
UniRef50_Q23YB5 Cluster: Protein kinase domain containing protei... 146 1e-33
UniRef50_Q22LX8 Cluster: Protein kinase domain containing protei... 146 1e-33
UniRef50_O62570 Cluster: Protein kinase C-related kinase; n=1; S... 146 1e-33
UniRef50_A0C3V8 Cluster: Chromosome undetermined scaffold_148, w... 146 1e-33
UniRef50_A0BWJ4 Cluster: Chromosome undetermined scaffold_132, w... 146 1e-33
UniRef50_P36583 Cluster: Protein kinase C-like 2; n=1; Schizosac... 146 1e-33
UniRef50_P36582 Cluster: Protein kinase C-like 1; n=2; Schizosac... 146 1e-33
UniRef50_UPI00006CC8B4 Cluster: Protein kinase domain containing... 146 1e-33
UniRef50_UPI0000499007 Cluster: hypothetical protein 139.t00021;... 146 1e-33
UniRef50_UPI000065FF34 Cluster: Homolog of Homo sapiens "Protein... 146 1e-33
UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative... 146 1e-33
UniRef50_A2EY79 Cluster: AGC family protein kinase; n=1; Trichom... 146 1e-33
UniRef50_A0DVL2 Cluster: Chromosome undetermined scaffold_66, wh... 146 1e-33
UniRef50_P43057 Cluster: Protein kinase C-like 1; n=4; Saccharom... 146 1e-33
UniRef50_UPI00006607B3 Cluster: RAC-beta serine/threonine-protei... 145 2e-33
UniRef50_Q584T1 Cluster: Rac serine-threonine kinase, putative; ... 145 2e-33
UniRef50_A2DB15 Cluster: AGC family protein kinase; n=1; Trichom... 145 2e-33
UniRef50_A0DPW4 Cluster: Chromosome undetermined scaffold_6, who... 145 2e-33
UniRef50_A0BSF2 Cluster: Chromosome undetermined scaffold_125, w... 145 2e-33
UniRef50_Q86ZV2 Cluster: Protein kinase C; n=1; Pichia pastoris|... 145 2e-33
UniRef50_UPI0000499868 Cluster: protein kinase; n=1; Entamoeba h... 144 4e-33
UniRef50_A2D9C1 Cluster: AGC family protein kinase; n=4; Trichom... 144 4e-33
UniRef50_Q6AX33 Cluster: Microtubule-associated serine/threonine... 144 4e-33
UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, wh... 144 5e-33
UniRef50_A0DUX2 Cluster: Chromosome undetermined scaffold_65, wh... 144 5e-33
UniRef50_Q00X68 Cluster: Cyclic nucleotide dependent protein kin... 144 7e-33
UniRef50_Q22S16 Cluster: Protein kinase domain containing protei... 144 7e-33
UniRef50_A0BN99 Cluster: Chromosome undetermined scaffold_118, w... 144 7e-33
UniRef50_P24723 Cluster: Protein kinase C eta type; n=44; Eumeta... 144 7e-33
UniRef50_A0E1G0 Cluster: Chromosome undetermined scaffold_73, wh... 143 1e-32
UniRef50_A0DUI6 Cluster: Chromosome undetermined scaffold_64, wh... 143 1e-32
UniRef50_UPI00006CD5AE Cluster: Protein kinase domain containing... 143 1e-32
UniRef50_UPI0000519F68 Cluster: PREDICTED: similar to cGMP-depen... 143 1e-32
UniRef50_Q84QE0 Cluster: Avr9/Cf-9 rapidly elicited protein 216;... 143 1e-32
UniRef50_Q54PK9 Cluster: Putative uncharacterized protein pdkB; ... 143 1e-32
UniRef50_A0E0G1 Cluster: Chromosome undetermined scaffold_71, wh... 143 1e-32
UniRef50_A0CNT4 Cluster: Chromosome undetermined scaffold_22, wh... 143 1e-32
UniRef50_Q6UB97 Cluster: Protein kinase C 1; n=7; Dikarya|Rep: P... 143 1e-32
UniRef50_UPI00006A0113 Cluster: UPI00006A0113 related cluster; n... 142 2e-32
UniRef50_Q9BMX6 Cluster: Phosphoinositide-dependent protein kina... 142 2e-32
UniRef50_A0BQE1 Cluster: Chromosome undetermined scaffold_120, w... 142 2e-32
UniRef50_A0EIN6 Cluster: Chromosome undetermined scaffold_99, wh... 142 2e-32
UniRef50_A0D680 Cluster: Chromosome undetermined scaffold_39, wh... 142 2e-32
UniRef50_Q04759 Cluster: Protein kinase C theta type; n=20; Eute... 142 2e-32
UniRef50_P34885 Cluster: Protein kinase C-like 1B; n=4; Bilateri... 142 2e-32
UniRef50_UPI00015B5903 Cluster: PREDICTED: similar to Melk prote... 142 3e-32
UniRef50_UPI0001509D2B Cluster: Protein kinase C terminal domain... 142 3e-32
UniRef50_O17874 Cluster: Putative uncharacterized protein; n=2; ... 142 3e-32
UniRef50_A5DM82 Cluster: Putative uncharacterized protein; n=1; ... 142 3e-32
UniRef50_UPI000065EC1B Cluster: Homolog of Fugu rubripes "Protei... 141 4e-32
UniRef50_A0CP93 Cluster: Chromosome undetermined scaffold_23, wh... 141 4e-32
UniRef50_UPI000069DCCB Cluster: UPI000069DCCB related cluster; n... 140 7e-32
UniRef50_Q229R8 Cluster: Protein kinase domain containing protei... 140 7e-32
UniRef50_A2F0I9 Cluster: AGC family protein kinase; n=1; Trichom... 140 7e-32
UniRef50_A2EE93 Cluster: AGC family protein kinase; n=1; Trichom... 140 7e-32
UniRef50_A2DA20 Cluster: AGC family protein kinase; n=2; Trichom... 140 7e-32
UniRef50_P38991 Cluster: Spindle assembly checkpoint kinase; n=5... 140 7e-32
UniRef50_Q9C098 Cluster: Serine/threonine-protein kinase DCLK3; ... 140 7e-32
UniRef50_UPI0000E46D98 Cluster: PREDICTED: similar to doublecort... 140 9e-32
UniRef50_Q4Q7M5 Cluster: Rac serine-threonine kinase, putative; ... 140 9e-32
UniRef50_Q22RR1 Cluster: Protein kinase domain containing protei... 140 9e-32
UniRef50_A2G1Q9 Cluster: AGC family protein kinase; n=1; Trichom... 140 9e-32
UniRef50_Q6BHW6 Cluster: Debaryomyces hansenii chromosome G of s... 140 9e-32
UniRef50_P83099 Cluster: Putative protein kinase C delta type ho... 140 9e-32
UniRef50_A0BYR7 Cluster: Chromosome undetermined scaffold_137, w... 140 1e-31
UniRef50_A6QRT1 Cluster: Serine/threonine-protein kinase psk1; n... 140 1e-31
UniRef50_UPI000150A7D8 Cluster: Protein kinase domain containing... 139 2e-31
UniRef50_Q5QFC4 Cluster: EnvDll2-01; n=1; Oikopleura dioica|Rep:... 139 2e-31
UniRef50_A2E474 Cluster: AGC family protein kinase; n=1; Trichom... 139 2e-31
UniRef50_A0DBI9 Cluster: Chromosome undetermined scaffold_44, wh... 139 2e-31
UniRef50_Q6BPN3 Cluster: Similar to sp|P38070 Saccharomyces cere... 139 2e-31
UniRef50_UPI00006CFE83 Cluster: Protein kinase domain containing... 139 2e-31
UniRef50_A0BZI1 Cluster: Chromosome undetermined scaffold_139, w... 139 2e-31
UniRef50_A0EEZ4 Cluster: Chromosome undetermined scaffold_92, wh... 138 3e-31
UniRef50_A4S6U9 Cluster: Predicted protein; n=2; Ostreococcus|Re... 138 4e-31
UniRef50_Q7PRV3 Cluster: ENSANGP00000020017; n=1; Anopheles gamb... 138 4e-31
UniRef50_Q3SEP0 Cluster: CGMP-dependent protein kinase 8-2; n=8;... 138 4e-31
UniRef50_O62569 Cluster: Serine/Threonine protein kinase; n=1; S... 138 4e-31
UniRef50_A2G3R6 Cluster: AGC family protein kinase; n=3; Trichom... 138 4e-31
UniRef50_A2FY70 Cluster: AGC family protein kinase; n=1; Trichom... 138 4e-31
UniRef50_A2FNQ5 Cluster: AGC family protein kinase; n=1; Trichom... 138 4e-31
UniRef50_A2FMG9 Cluster: AGC family protein kinase; n=2; Trichom... 138 4e-31
UniRef50_A7TMA2 Cluster: Putative uncharacterized protein; n=1; ... 138 4e-31
UniRef50_P24583 Cluster: Protein kinase C-like 1; n=5; Ascomycot... 138 4e-31
UniRef50_UPI0000DB6ED3 Cluster: PREDICTED: similar to CG17528-PC... 138 5e-31
UniRef50_UPI00005A4286 Cluster: PREDICTED: similar to doublecort... 138 5e-31
UniRef50_Q0D3M5 Cluster: Os07g0678300 protein; n=3; Oryza sativa... 138 5e-31
UniRef50_A5DZ73 Cluster: Putative uncharacterized protein; n=1; ... 138 5e-31
UniRef50_A4RL90 Cluster: Putative uncharacterized protein; n=1; ... 138 5e-31
UniRef50_Q62074 Cluster: Protein kinase C iota type; n=26; Eumet... 138 5e-31
UniRef50_P41743 Cluster: Protein kinase C iota type; n=97; Bilat... 138 5e-31
UniRef50_UPI0000D562F1 Cluster: PREDICTED: similar to CG3324-PA;... 137 6e-31
UniRef50_A0DDW7 Cluster: Chromosome undetermined scaffold_47, wh... 137 6e-31
UniRef50_Q4RM42 Cluster: Chromosome 10 SCAF15019, whole genome s... 137 8e-31
UniRef50_Q233E6 Cluster: Protein kinase domain containing protei... 137 8e-31
UniRef50_Q6FJ43 Cluster: Similar to sp|P24583 Saccharomyces cere... 137 8e-31
UniRef50_A0BC68 Cluster: Chromosome undetermined scaffold_10, wh... 136 1e-30
UniRef50_Q869W6 Cluster: Similar to Xenopus laevis (African claw... 136 1e-30
UniRef50_A0BMD5 Cluster: Chromosome undetermined scaffold_116, w... 136 1e-30
UniRef50_Q6CPN3 Cluster: Similar to sgd|S0002874 Saccharomyces c... 136 1e-30
UniRef50_Q9UK32 Cluster: Ribosomal protein S6 kinase alpha-6; n=... 136 1e-30
UniRef50_UPI0000DB76CC Cluster: PREDICTED: similar to serine/thr... 136 2e-30
UniRef50_A2FZ96 Cluster: AGC family protein kinase; n=1; Trichom... 136 2e-30
UniRef50_A2FBN5 Cluster: AGC family protein kinase; n=1; Trichom... 136 2e-30
UniRef50_A0D8K8 Cluster: Chromosome undetermined scaffold_41, wh... 136 2e-30
UniRef50_Q8IY84 Cluster: Serine/threonine-protein kinase NIM1; n... 136 2e-30
UniRef50_Q96NX5 Cluster: Calcium/calmodulin-dependent protein ki... 136 2e-30
UniRef50_UPI0000519D29 Cluster: PREDICTED: similar to maternal e... 135 3e-30
UniRef50_Q12706 Cluster: Serine/threonine-protein kinase psk1; n... 135 3e-30
UniRef50_P34722 Cluster: Protein kinase C-like 1; n=3; Caenorhab... 135 3e-30
UniRef50_UPI00003C0E92 Cluster: PREDICTED: similar to CG4290-PA;... 135 3e-30
UniRef50_A0D329 Cluster: Chromosome undetermined scaffold_36, wh... 135 3e-30
UniRef50_A0BQV0 Cluster: Chromosome undetermined scaffold_121, w... 135 3e-30
UniRef50_A1CKA9 Cluster: Serine/threonine protein kinase, putati... 135 3e-30
UniRef50_A2DL59 Cluster: AGC family protein kinase; n=1; Trichom... 134 4e-30
UniRef50_A0BCL5 Cluster: Chromosome undetermined scaffold_10, wh... 134 4e-30
UniRef50_O22932 Cluster: CBL-interacting serine/threonine-protei... 134 4e-30
UniRef50_UPI00004D2369 Cluster: UPI00004D2369 related cluster; n... 134 6e-30
UniRef50_Q54DF2 Cluster: Putative uncharacterized protein mrkA; ... 134 6e-30
UniRef50_A3FPS4 Cluster: OSK4, putative; n=2; Cryptosporidium|Re... 134 6e-30
UniRef50_A0E900 Cluster: Chromosome undetermined scaffold_83, wh... 134 6e-30
UniRef50_UPI00015B4C4D Cluster: PREDICTED: similar to p90 riboso... 134 8e-30
UniRef50_UPI00006CB12C Cluster: Protein kinase domain containing... 134 8e-30
UniRef50_A0C4H5 Cluster: Chromosome undetermined scaffold_149, w... 134 8e-30
UniRef50_Q4E3J2 Cluster: Serine/threonine protein kinase, putati... 133 1e-29
UniRef50_Q22A18 Cluster: Protein kinase domain containing protei... 133 1e-29
UniRef50_A0DYT2 Cluster: Chromosome undetermined scaffold_7, who... 133 1e-29
UniRef50_A0DBI7 Cluster: Chromosome undetermined scaffold_44, wh... 133 1e-29
UniRef50_Q6CTI4 Cluster: Similar to sp|Q12236 Saccharomyces cere... 133 1e-29
UniRef50_Q6BIK8 Cluster: Similar to CA1971|CaPKH2 Candida albica... 133 1e-29
UniRef50_P34100 Cluster: Developmentally-regulated protein kinas... 133 1e-29
UniRef50_UPI00015B58A4 Cluster: PREDICTED: similar to serine/thr... 133 1e-29
UniRef50_Q4RRU3 Cluster: Chromosome 7 SCAF15001, whole genome sh... 133 1e-29
UniRef50_A2X165 Cluster: Putative uncharacterized protein; n=2; ... 133 1e-29
UniRef50_Q9W532 Cluster: CG4290-PA; n=8; Coelomata|Rep: CG4290-P... 133 1e-29
UniRef50_A0E1C0 Cluster: Chromosome undetermined scaffold_73, wh... 133 1e-29
UniRef50_O14965 Cluster: Serine/threonine-protein kinase 6; n=40... 133 1e-29
UniRef50_Q90ZY5 Cluster: Protein kinase Chk2; n=4; Danio rerio|R... 132 2e-29
UniRef50_Q4RJK7 Cluster: Chromosome 3 SCAF15037, whole genome sh... 132 2e-29
UniRef50_A2BFU1 Cluster: Novel protein; n=6; Euteleostomi|Rep: N... 132 2e-29
UniRef50_Q8SWT6 Cluster: RE56868p; n=4; Drosophila melanogaster|... 132 2e-29
UniRef50_Q54WX4 Cluster: Putative uncharacterized protein aurB; ... 132 2e-29
UniRef50_A0E941 Cluster: Chromosome undetermined scaffold_84, wh... 132 2e-29
UniRef50_Q8SSJ0 Cluster: PROTEIN KINASE C; n=1; Encephalitozoon ... 132 2e-29
UniRef50_Q8C050 Cluster: Ribosomal protein S6 kinase alpha-5; n=... 132 2e-29
UniRef50_Q6BVA0 Cluster: Spindle assembly checkpoint kinase; n=1... 132 2e-29
UniRef50_UPI00015B57A5 Cluster: PREDICTED: similar to CG10261-PE... 132 2e-29
UniRef50_UPI000069F1C6 Cluster: UPI000069F1C6 related cluster; n... 132 2e-29
UniRef50_A4I4Q9 Cluster: Serine/threonine protein kinase, putati... 132 2e-29
UniRef50_A0CJ09 Cluster: Chromosome undetermined scaffold_19, wh... 132 2e-29
UniRef50_A0BFR1 Cluster: Chromosome undetermined scaffold_104, w... 132 2e-29
UniRef50_O75582 Cluster: Ribosomal protein S6 kinase alpha-5; n=... 132 2e-29
UniRef50_UPI00006CF9D0 Cluster: Protein kinase domain containing... 132 3e-29
UniRef50_UPI00006CBA83 Cluster: Protein kinase domain containing... 132 3e-29
UniRef50_UPI0000499138 Cluster: hypothetical protein 53.t00028; ... 132 3e-29
UniRef50_Q9XF67 Cluster: 3-phosphoinositide-dependent protein ki... 132 3e-29
UniRef50_Q24FD5 Cluster: Protein kinase domain containing protei... 132 3e-29
UniRef50_Q23TE4 Cluster: Protein kinase domain containing protei... 132 3e-29
UniRef50_A2GEQ5 Cluster: AGC family protein kinase; n=1; Trichom... 132 3e-29
UniRef50_A2DRK1 Cluster: AGC family protein kinase; n=1; Trichom... 132 3e-29
UniRef50_A0E1E2 Cluster: Chromosome undetermined scaffold_73, wh... 132 3e-29
UniRef50_Q6FT84 Cluster: Similar to sp|Q12236 Saccharomyces cere... 132 3e-29
UniRef50_UPI00006CBF34 Cluster: Protein kinase domain containing... 131 4e-29
UniRef50_A7S1C2 Cluster: Predicted protein; n=1; Nematostella ve... 131 4e-29
UniRef50_A2EX40 Cluster: AGC family protein kinase; n=4; Trichom... 131 4e-29
UniRef50_A0BPA1 Cluster: Chromosome undetermined scaffold_12, wh... 131 4e-29
UniRef50_Q55U80 Cluster: Putative uncharacterized protein; n=3; ... 131 4e-29
UniRef50_UPI00015B41D5 Cluster: PREDICTED: hypothetical protein;... 131 5e-29
UniRef50_Q9SX42 Cluster: F14I3.15 protein; n=2; Arabidopsis thal... 131 5e-29
UniRef50_O96942 Cluster: Serine /threonine protein kinase; n=1; ... 131 5e-29
UniRef50_A0E6L8 Cluster: Chromosome undetermined scaffold_8, who... 131 5e-29
UniRef50_A0D0C4 Cluster: Chromosome undetermined scaffold_33, wh... 131 5e-29
UniRef50_Q5A3V9 Cluster: Likely protein kinase; n=5; Saccharomyc... 131 5e-29
UniRef50_UPI00006CC414 Cluster: Protein kinase domain containing... 130 7e-29
UniRef50_Q27393 Cluster: Aurora; n=7; Fungi/Metazoa group|Rep: A... 130 7e-29
UniRef50_Q6CBU3 Cluster: Yarrowia lipolytica chromosome C of str... 130 7e-29
UniRef50_UPI00006CFBB4 Cluster: Protein kinase domain containing... 130 9e-29
UniRef50_Q54UZ1 Cluster: Putative uncharacterized protein; n=1; ... 130 9e-29
UniRef50_Q16QY2 Cluster: Ribosomal protein S6 kinase, 90kD, poly... 130 9e-29
UniRef50_A2ET74 Cluster: AGC family protein kinase; n=1; Trichom... 130 9e-29
UniRef50_A0BGU9 Cluster: Chromosome undetermined scaffold_107, w... 130 9e-29
UniRef50_P53350 Cluster: Serine/threonine-protein kinase PLK1; n... 130 9e-29
UniRef50_Q6P5Z2 Cluster: Serine/threonine-protein kinase N3; n=2... 130 9e-29
UniRef50_UPI0000F20BD0 Cluster: PREDICTED: hypothetical protein;... 130 1e-28
UniRef50_UPI0000499488 Cluster: hypothetical protein 137.t00011;... 130 1e-28
UniRef50_UPI00006A16D5 Cluster: UPI00006A16D5 related cluster; n... 130 1e-28
UniRef50_UPI00006A08A1 Cluster: Serine/threonine-protein kinase ... 130 1e-28
UniRef50_Q01B06 Cluster: CAMP-dependent protein kinase catalytic... 130 1e-28
UniRef50_A2GBV0 Cluster: AGC family protein kinase; n=1; Trichom... 130 1e-28
UniRef50_A2FYT0 Cluster: AGC family protein kinase; n=2; Trichom... 130 1e-28
UniRef50_A2DQE8 Cluster: AGC family protein kinase; n=1; Trichom... 130 1e-28
UniRef50_Q2KFW9 Cluster: Putative uncharacterized protein; n=2; ... 130 1e-28
UniRef50_Q9Y7J6 Cluster: Serine/threonine-protein kinase ppk21; ... 130 1e-28
UniRef50_Q6C3J2 Cluster: Spindle assembly checkpoint kinase; n=1... 130 1e-28
UniRef50_O59790 Cluster: Serine/threonine-protein kinase ark1; n... 130 1e-28
UniRef50_UPI00015B638D Cluster: PREDICTED: similar to aurora kin... 129 2e-28
UniRef50_UPI00015B507B Cluster: PREDICTED: similar to cell cycle... 129 2e-28
UniRef50_UPI000155511B Cluster: PREDICTED: similar to Calcium/ca... 129 2e-28
UniRef50_UPI0000D9C1EE Cluster: PREDICTED: similar to calcium/ca... 129 2e-28
UniRef50_UPI0000D55D86 Cluster: PREDICTED: similar to SNF1-like ... 129 2e-28
UniRef50_UPI000049857F Cluster: protein kinase; n=1; Entamoeba h... 129 2e-28
UniRef50_A0C6X0 Cluster: Chromosome undetermined scaffold_153, w... 129 2e-28
UniRef50_Q8IU85 Cluster: Calcium/calmodulin-dependent protein ki... 129 2e-28
UniRef50_UPI0001509E5E Cluster: Streptococcal surface antigen re... 129 2e-28
UniRef50_Q4SL09 Cluster: Chromosome 17 SCAF14563, whole genome s... 129 2e-28
UniRef50_Q7R0B9 Cluster: GLP_608_36888_34957; n=1; Giardia lambl... 129 2e-28
UniRef50_Q23386 Cluster: Putative uncharacterized protein twk-4;... 129 2e-28
UniRef50_UPI00015B53AD Cluster: PREDICTED: similar to RHO kinase... 128 3e-28
UniRef50_UPI000150AAA4 Cluster: Protein kinase domain containing... 128 3e-28
UniRef50_UPI00006CBD02 Cluster: Protein kinase domain containing... 128 3e-28
UniRef50_Q4Q898 Cluster: Zinc finger protein kinase-like; n=3; L... 128 3e-28
UniRef50_A2FYJ4 Cluster: AGC family protein kinase; n=1; Trichom... 128 3e-28
UniRef50_A0DV61 Cluster: Chromosome undetermined scaffold_65, wh... 128 3e-28
UniRef50_A0CZE9 Cluster: Chromosome undetermined scaffold_32, wh... 128 3e-28
UniRef50_O88445 Cluster: Serine/threonine-protein kinase 13; n=7... 128 3e-28
UniRef50_UPI0000F1EB23 Cluster: PREDICTED: similar to cGMP-depen... 128 4e-28
UniRef50_UPI000069EAF4 Cluster: UPI000069EAF4 related cluster; n... 128 4e-28
UniRef50_Q4RPP3 Cluster: Chromosome 12 SCAF15007, whole genome s... 128 4e-28
UniRef50_A7PMI1 Cluster: Chromosome chr14 scaffold_21, whole gen... 128 4e-28
UniRef50_Q384J7 Cluster: Protein kinase, putative; n=7; Trypanos... 128 4e-28
UniRef50_P32562 Cluster: Cell cycle serine/threonine-protein kin... 128 4e-28
UniRef50_UPI0000DB6ECE Cluster: PREDICTED: similar to loki CG108... 128 5e-28
UniRef50_Q4R1K7 Cluster: Aurora kinase; n=5; Eukaryota|Rep: Auro... 128 5e-28
UniRef50_Q54CY9 Cluster: Putative uncharacterized protein; n=1; ... 128 5e-28
UniRef50_A2EWI0 Cluster: AGC family protein kinase; n=2; Trichom... 128 5e-28
UniRef50_Q02956 Cluster: Protein kinase C zeta type; n=60; Bilat... 128 5e-28
UniRef50_Q5SP91 Cluster: Novel protein similar to rho-associated... 127 7e-28
UniRef50_Q4T9Z5 Cluster: Chromosome undetermined SCAF7480, whole... 127 7e-28
UniRef50_Q5DTG3 Cluster: MKIAA4230 protein; n=16; Bilateria|Rep:... 127 7e-28
UniRef50_Q6V8K6 Cluster: Gliding motility related CaM kinase; n=... 127 7e-28
UniRef50_Q8MVX2 Cluster: Putative serine/threonine protein kinas... 127 7e-28
UniRef50_Q24JF9 Cluster: Protein kinase domain containing protei... 127 7e-28
UniRef50_Q22XQ2 Cluster: Protein kinase domain containing protei... 127 7e-28
UniRef50_Q22DW7 Cluster: Protein kinase domain containing protei... 127 7e-28
UniRef50_A2EAS8 Cluster: CAMK family protein kinase; n=1; Tricho... 127 7e-28
UniRef50_A0EAF2 Cluster: Chromosome undetermined scaffold_86, wh... 127 7e-28
UniRef50_Q6FNH5 Cluster: Candida glabrata strain CBS138 chromoso... 127 7e-28
UniRef50_P25323 Cluster: Myosin light chain kinase; n=4; Dictyos... 127 7e-28
UniRef50_Q9P0L2 Cluster: Serine/threonine-protein kinase MARK1; ... 127 7e-28
UniRef50_UPI0000E4822C Cluster: PREDICTED: similar to KIAA0619 p... 127 9e-28
UniRef50_UPI000023D36F Cluster: hypothetical protein FG08701.1; ... 127 9e-28
UniRef50_Q2QSC9 Cluster: Protein kinase domain containing protei... 127 9e-28
UniRef50_A7QZS3 Cluster: Chromosome chr13 scaffold_286, whole ge... 127 9e-28
UniRef50_Q16JY5 Cluster: Calcium/calmodulin-dependent protein ki... 127 9e-28
UniRef50_Q7SCT1 Cluster: Putative uncharacterized protein NCU090... 127 9e-28
UniRef50_P92937 Cluster: CBL-interacting serine/threonine-protei... 127 9e-28
UniRef50_UPI0001560DD3 Cluster: PREDICTED: similar to MAP/microt... 126 1e-27
UniRef50_Q6P954 Cluster: Zgc:73231; n=2; Danio rerio|Rep: Zgc:73... 126 1e-27
UniRef50_Q9FJ55 Cluster: Serine/threonine protein kinase; n=14; ... 126 1e-27
UniRef50_A7QFL3 Cluster: Chromosome chr8 scaffold_88, whole geno... 126 1e-27
UniRef50_A7QA52 Cluster: Chromosome undetermined scaffold_69, wh... 126 1e-27
UniRef50_Q55FT4 Cluster: Putative uncharacterized protein tsuA; ... 126 1e-27
UniRef50_Q6BR88 Cluster: Similar to CA5851|CaKIN2 Candida albica... 126 1e-27
UniRef50_Q5KM47 Cluster: CAMP-dependent protein kinase, putative... 126 1e-27
UniRef50_UPI000065FBEC Cluster: Ribosomal protein S6 kinase alph... 126 2e-27
UniRef50_Q5SP93 Cluster: Novel protein similar to part of rho-as... 126 2e-27
UniRef50_Q94DT7 Cluster: OsPK4-like protein; n=4; Oryza sativa|R... 126 2e-27
UniRef50_Q00TK7 Cluster: Protein kinase, putative; n=2; Ostreoco... 126 2e-27
UniRef50_Q93531 Cluster: Putative uncharacterized protein twk-23... 126 2e-27
UniRef50_Q54MH0 Cluster: Putative uncharacterized protein fhkD; ... 126 2e-27
UniRef50_A2EKR5 Cluster: CAMK family protein kinase; n=3; Tricho... 126 2e-27
UniRef50_A2EBI4 Cluster: CAMK family protein kinase; n=1; Tricho... 126 2e-27
UniRef50_A0CKQ4 Cluster: Chromosome undetermined scaffold_2, who... 126 2e-27
UniRef50_Q15835 Cluster: Rhodopsin kinase precursor; n=28; Eutel... 126 2e-27
UniRef50_UPI0000F20AB2 Cluster: PREDICTED: hypothetical protein;... 126 2e-27
UniRef50_Q2QAV0 Cluster: Fused; n=3; core eudicotyledons|Rep: Fu... 126 2e-27
UniRef50_O18645 Cluster: CG3051-PA, isoform A; n=9; Coelomata|Re... 126 2e-27
UniRef50_Q5AAN6 Cluster: Likely protein kinase; n=1; Candida alb... 126 2e-27
UniRef50_Q5VT25 Cluster: Serine/threonine-protein kinase MRCK al... 126 2e-27
UniRef50_Q9UQB9 Cluster: Serine/threonine-protein kinase 13; n=8... 126 2e-27
UniRef50_UPI0000499CC6 Cluster: protein kinase; n=14; Entamoeba ... 125 3e-27
UniRef50_Q6DI71 Cluster: Dmpk protein; n=4; Murinae|Rep: Dmpk pr... 125 3e-27
UniRef50_Q57VI9 Cluster: Protein kinase, putative; n=3; Trypanos... 125 3e-27
UniRef50_P92199 Cluster: Lethal protein 502; n=2; Caenorhabditis... 125 3e-27
UniRef50_A0DXJ1 Cluster: Chromosome undetermined scaffold_69, wh... 125 3e-27
UniRef50_Q6DT37 Cluster: Serine/threonine-protein kinase MRCK ga... 125 3e-27
UniRef50_P13677 Cluster: Protein kinase C, eye isozyme (EC 2.7.1... 125 3e-27
UniRef50_UPI00015B60DA Cluster: PREDICTED: similar to calcium/ca... 125 4e-27
UniRef50_Q4DXB5 Cluster: Protein kinase, putative; n=3; Trypanos... 125 4e-27
UniRef50_Q24FU4 Cluster: Protein kinase domain containing protei... 125 4e-27
UniRef50_A6YQS3 Cluster: TASK two-pore domain potassium channel;... 125 4e-27
UniRef50_A2DBY9 Cluster: CAMK family protein kinase; n=2; Tricho... 125 4e-27
UniRef50_A0C8T1 Cluster: Chromosome undetermined scaffold_159, w... 125 4e-27
UniRef50_Q9V3I5 Cluster: Chromosomal serine/threonine-protein ki... 125 4e-27
UniRef50_UPI00006CAF11 Cluster: Protein kinase domain containing... 124 5e-27
UniRef50_A7PBE5 Cluster: Chromosome chr16 scaffold_10, whole gen... 124 5e-27
UniRef50_Q9W1B0 Cluster: CG4012-PA; n=3; Sophophora|Rep: CG4012-... 124 5e-27
UniRef50_Q7QXR8 Cluster: GLP_399_8255_9553; n=1; Giardia lamblia... 124 5e-27
UniRef50_Q21271 Cluster: Aurora/ipl1 related kinase protein 1; n... 124 5e-27
UniRef50_A7RLC5 Cluster: Predicted protein; n=1; Nematostella ve... 124 5e-27
UniRef50_A2EZG8 Cluster: AGC family protein kinase; n=1; Trichom... 124 5e-27
UniRef50_A7TFP9 Cluster: Putative uncharacterized protein; n=1; ... 124 5e-27
UniRef50_Q9NRP7 Cluster: Serine/threonine-protein kinase 36; n=2... 124 5e-27
UniRef50_Q96L34 Cluster: MAP/microtubule affinity-regulating kin... 124 5e-27
UniRef50_Q8N568 Cluster: Serine/threonine-protein kinase DCLK2; ... 124 5e-27
UniRef50_UPI0000E4986C Cluster: PREDICTED: similar to KIAA0999 p... 124 6e-27
UniRef50_UPI0000DB7653 Cluster: PREDICTED: similar to CG15072-PA... 124 6e-27
UniRef50_Q4SPC4 Cluster: Chromosome undetermined SCAF14539, whol... 124 6e-27
UniRef50_Q4SIP8 Cluster: Chromosome 21 SCAF14577, whole genome s... 124 6e-27
UniRef50_A7UAR9 Cluster: Checkpoint kinase 2; n=1; Oncorhynchus ... 124 6e-27
UniRef50_Q016K3 Cluster: Snf1 related kinase 1; n=1; Ostreococcu... 124 6e-27
UniRef50_Q17E44 Cluster: Map/microtubule affinity-regulating kin... 124 6e-27
UniRef50_O01583 Cluster: Temporarily assigned gene name protein ... 124 6e-27
UniRef50_A0DYJ0 Cluster: Chromosome undetermined scaffold_7, who... 124 6e-27
UniRef50_A0C3X2 Cluster: Chromosome undetermined scaffold_148, w... 124 6e-27
UniRef50_A5DVI4 Cluster: Cell cycle serine/threonine-protein kin... 124 6e-27
UniRef50_O08679 Cluster: Serine/threonine-protein kinase MARK2; ... 124 6e-27
UniRef50_Q9JLM8 Cluster: Serine/threonine-protein kinase DCLK1; ... 124 6e-27
UniRef50_O96017 Cluster: Serine/threonine-protein kinase Chk2; n... 124 6e-27
UniRef50_Q9VKN7 Cluster: Serine/threonine-protein kinase Ial; n=... 124 6e-27
UniRef50_P45894 Cluster: 5'-AMP-activated protein kinase catalyt... 124 6e-27
UniRef50_UPI000069F393 Cluster: UPI000069F393 related cluster; n... 124 8e-27
UniRef50_UPI0000EB1830 Cluster: Serine/threonine-protein kinase ... 124 8e-27
UniRef50_A2DW97 Cluster: CAMK family protein kinase; n=2; Tricho... 124 8e-27
UniRef50_A0C7R9 Cluster: Chromosome undetermined scaffold_156, w... 124 8e-27
>UniRef50_Q9VYY5 Cluster: CG1756-PA; n=7; Endopterygota|Rep:
CG1756-PA - Drosophila melanogaster (Fruit fly)
Length = 385
Score = 357 bits (877), Expect = 6e-97
Identities = 185/297 (62%), Positives = 223/297 (75%), Gaps = 15/297 (5%)
Query: 185 VFRALEYPAEMAKQDFHRERVLSERWNLIRFVAQWTNGTEYFNGVEELLSHHLAIYEKVL 244
+FR LE PAE+ + ++ V + R RF+ N TE N ++ELLS LA YE +
Sbjct: 56 IFRHLERPAEVERLSHLKDIVKTHRE---RFLHTILNNTEVHN-LDELLSFELAKYEAAV 111
Query: 245 EEASSDGISLEVEKNFPPTEERWSILQAVFFSSTVLTTIGYGNIVPVTFWGRLFCIAYAL 304
++A+ G+ + +K+FP ERWSILQAVFFSSTVLTTIGYGNIVPVT GR+FCI +AL
Sbjct: 112 QQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIVPVTTGGRVFCICFAL 171
Query: 305 IGIPFTLTVIADLGRVFATCVSFIAKHLPSPPKCCTRVTEANPAGQRSLYALGAVGFLFV 364
IGIPFTLTVIAD GR+FAT VS KH+P+ PK N G+ YA+ AVGFL V
Sbjct: 172 IGIPFTLTVIADWGRLFATAVSVFGKHMPTKPKF------TNFIGKTWFYAILAVGFLGV 225
Query: 365 YLSAGAGLFKMWEDDWTFYDGFYFCFITMTTIGFGDIVPKRPKYMLLCTLYILIGLALTS 424
YL+AGAGL +WEDDWTF+DGFYFCFITMTTIGFGD+VPK+P YMLLCTLYILIGLALTS
Sbjct: 226 YLAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGFGDLVPKKPNYMLLCTLYILIGLALTS 285
Query: 425 TIIELVRRQYARSWQQLRALSGPLADTLRRLGD-AGRGVDVSSLHSDLRKVLTVIAP 480
TIIELVRRQYA SW +L+ LSGP+A+TLRRLG+ AG G+D ++ L+KVLTV P
Sbjct: 286 TIIELVRRQYATSWAKLQELSGPMAETLRRLGETAGTGLD----YTALQKVLTVSMP 338
Score = 36.3 bits (80), Expect = 2.1
Identities = 15/32 (46%), Positives = 22/32 (68%)
Query: 528 LEAAVEAVIRDITSPVQQKPPIVQIVIYESSV 559
LEA A+++++ KP ++QIVIYESSV
Sbjct: 354 LEAITNAILKEVKEAQNNKPKVLQIVIYESSV 385
>UniRef50_P22612 Cluster: cAMP-dependent protein kinase,
gamma-catalytic subunit; n=18; Coelomata|Rep:
cAMP-dependent protein kinase, gamma-catalytic subunit -
Homo sapiens (Human)
Length = 351
Score = 249 bits (609), Expect = 2e-64
Identities = 104/185 (56%), Positives = 147/185 (79%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ KDN Y+Y ++ Y GGE+++ ++++G FSEP + FYAAQ+VLA++YLH ++
Sbjct: 105 VKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLI 164
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
HRDLKPEN+L+ GY+++ DFGF K +K RTWTLCGTPEYLAPE+ILSKGY+ VDWWA
Sbjct: 165 HRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWA 224
Query: 121 LGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
LGVLIYEM FPPFY+ +PI++YEKI++G+ + P ++ K L+++LL+VD TKR+G+
Sbjct: 225 LGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGN 284
Query: 181 LKAGV 185
L+ GV
Sbjct: 285 LRNGV 289
>UniRef50_P17612 Cluster: cAMP-dependent protein kinase,
alpha-catalytic subunit; n=158; Bilateria|Rep:
cAMP-dependent protein kinase, alpha-catalytic subunit -
Homo sapiens (Human)
Length = 351
Score = 248 bits (606), Expect = 4e-64
Identities = 104/185 (56%), Positives = 147/185 (79%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L+F+ KDN +Y ++ Y GGE+++ ++++G FSEP ++FYAAQ+VL EYLH ++
Sbjct: 105 VKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLI 164
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
+RDLKPEN+L+ GYI++ DFGF K +K RTWTLCGTPEYLAPE+ILSKGY+ VDWWA
Sbjct: 165 YRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWA 224
Query: 121 LGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
LGVLIYEM A +PPF++ +PI++YEKI++G+ + P + + K L++NLL+VD TKR+G+
Sbjct: 225 LGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGN 284
Query: 181 LKAGV 185
LK GV
Sbjct: 285 LKNGV 289
>UniRef50_Q17JG1 Cluster: Camp-dependent protein kinase catalytic
subunit; n=1; Aedes aegypti|Rep: Camp-dependent protein
kinase catalytic subunit - Aedes aegypti (Yellowfever
mosquito)
Length = 405
Score = 229 bits (559), Expect = 2e-58
Identities = 95/186 (51%), Positives = 137/186 (73%), Gaps = 2/186 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++++ KDN Y+Y ++P+ GGE++ L++K F E ++FY AQ+ LA+EYLHH +++
Sbjct: 157 VNMECCFKDNSYIYLVMPFVCGGEMFALLRKSKRFGEEQAKFYGAQVALAIEYLHHMNLI 216
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
+RDLKPEN+L+ GY+K+ DFGFCK+I+ RTWTLCGTPEYLAPE+I SKGY VDWW+
Sbjct: 217 YRDLKPENILIDMKGYVKITDFGFCKLIRDRTWTLCGTPEYLAPEIIQSKGYGKSVDWWS 276
Query: 121 LGVLIYEMIAAFPPFY--SSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRY 178
G+L+YEM A + PFY SS+ + L+EKI G+F+ P K L++N+L D T+R+
Sbjct: 277 FGILLYEMAAGYTPFYTNSSDHMVLFEKICKGKFRFPAGFGGDLKHLIQNILHADLTRRF 336
Query: 179 GSLKAG 184
G+LK G
Sbjct: 337 GNLKNG 342
>UniRef50_Q4E4S9 Cluster: Protein kinase A catalytic subunit isoform
1, putative; n=8; Trypanosomatidae|Rep: Protein kinase A
catalytic subunit isoform 1, putative - Trypanosoma
cruzi
Length = 387
Score = 217 bits (531), Expect = 5e-55
Identities = 95/185 (51%), Positives = 130/185 (70%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
+D+ VYF+L + GGE++T ++ G F +++FY A++VLA EYLH +++RDLKPE
Sbjct: 146 QDDRRVYFVLEFVVGGEMFTHLRSAGRFPNDVAKFYHAEIVLAFEYLHSKDIIYRDLKPE 205
Query: 68 NVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
N+L+ S G++K+ DFGF K + RT+TLCGTPEYLAPE+I SKG+ VDWW +GVL+YE
Sbjct: 206 NLLLDSKGHVKVTDFGFAKKVPERTFTLCGTPEYLAPEVIQSKGHGKAVDWWTMGVLLYE 265
Query: 128 MIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFR 187
IA +PPFY P + YEKIL+G+FK P + LVK LL+ D TKR G+LK GV
Sbjct: 266 FIAGYPPFYDDTPFRTYEKILSGRFKFPSWFDARARDLVKGLLQTDHTKRLGTLKGGVAD 325
Query: 188 ALEYP 192
+P
Sbjct: 326 VKNHP 330
>UniRef50_Q8J0I6 Cluster: CAMP-dependent protein kinase A catalytic
subunit; n=4; Filobasidiella neoformans|Rep:
CAMP-dependent protein kinase A catalytic subunit -
Cryptococcus neoformans var. grubii (Filobasidiella
neoformans var.grubii)
Length = 567
Score = 213 bits (520), Expect = 1e-53
Identities = 90/192 (46%), Positives = 137/192 (71%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L T +D + VY +L Y GGEL++ +++ G FS +++FY A +VLA+EYLH +++
Sbjct: 289 VELHATYQDQINVYMLLFYIPGGELFSHLRRAGRFSADVTRFYLASIVLAIEYLHSRNII 348
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
+RDLKPEN+L+ GY+++ADFGF K+++ RT+TLCGTPEYLAPE++LS+G+ VDWWA
Sbjct: 349 YRDLKPENLLLDRHGYLRIADFGFAKVVQDRTFTLCGTPEYLAPEIVLSQGHGKAVDWWA 408
Query: 121 LGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
LG+L +EM+A +PPF+ P+ +YEKIL G P ++ K L++ LL D +KR G+
Sbjct: 409 LGILGFEMLAGYPPFFDDHPLGIYEKILRGDIAFPSHIDPFAKDLIRGLLTADRSKRLGN 468
Query: 181 LKAGVFRALEYP 192
L+ G + +P
Sbjct: 469 LRGGAKDVMGHP 480
>UniRef50_P51817 Cluster: Serine/threonine-protein kinase PRKX;
n=54; Eukaryota|Rep: Serine/threonine-protein kinase
PRKX - Homo sapiens (Human)
Length = 358
Score = 210 bits (514), Expect = 6e-53
Identities = 91/182 (50%), Positives = 127/182 (69%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L +T D ++Y ++ Y GGEL++ ++ G FS FY+A+++ A+EYLH +V+R
Sbjct: 112 LFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYR 171
Query: 63 DLKPENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALG 122
DLKPEN+L+ G+IKL DFGF K + RTWTLCGTPEYLAPE+I SKG+ VDWWALG
Sbjct: 172 DLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALG 231
Query: 123 VLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLK 182
+LI+EM++ FPPF+ P +Y+KIL G+ P ++ K L+K LL VD T+R G++K
Sbjct: 232 ILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMK 291
Query: 183 AG 184
G
Sbjct: 292 NG 293
>UniRef50_Q33DX4 Cluster: Putative cyclic AMP-dependent protein
kinase catalytic subunit; n=1; Schizophyllum
commune|Rep: Putative cyclic AMP-dependent protein
kinase catalytic subunit - Schizophyllum commune
(Bracket fungus)
Length = 432
Score = 210 bits (512), Expect = 1e-52
Identities = 89/187 (47%), Positives = 129/187 (68%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D++ VY ++ Y GGEL+T +++ F+ +++FY A ++LAL YLH ++++RDLK
Sbjct: 177 TFQDSLNVYMLMSYVPGGELFTHLRRAQRFTPDVTRFYLATIILALRYLHSFNIIYRDLK 236
Query: 66 PENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
PEN+L+ S GY++L DFGF KI+ RTWTLCGTPEYLAPE+I S G+ DWWA+GVL
Sbjct: 237 PENLLLDSRGYLRLTDFGFAKIVDDRTWTLCGTPEYLAPEIIQSDGHGKAADWWAVGVLC 296
Query: 126 YEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGV 185
YEM+ +PPF+ P +YEKIL G P +M + ++L++ L D TKR G++ G
Sbjct: 297 YEMLVGYPPFFDESPYGIYEKILDGHIHWPRSMDPLSRSLIRAFLNPDRTKRLGNMIGGP 356
Query: 186 FRALEYP 192
LE+P
Sbjct: 357 QDVLEHP 363
>UniRef50_O13367 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=6; Eukaryota|Rep: CAMP-dependent protein
kinase catalytic subunit - Ustilago maydis (Smut fungus)
Length = 398
Score = 210 bits (512), Expect = 1e-52
Identities = 87/185 (47%), Positives = 129/185 (69%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
+D+ Y ++ Y GGE+++ +++ G FS +++FY + +VLA+EYLH VV+RDLKPE
Sbjct: 150 QDSKNCYMLMEYVVGGEIFSYLRRAGHFSADVARFYISTIVLAIEYLHSNKVVYRDLKPE 209
Query: 68 NVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
N+L+ S+GY K+ DFGF K ++ RTWTLCGTPEYLAPE+I G+ VDWW+LG+L++E
Sbjct: 210 NLLIDSNGYTKITDFGFAKEVEDRTWTLCGTPEYLAPEIIQCSGHGSAVDWWSLGILLFE 269
Query: 128 MIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFR 187
M+A +PPFY PI +YEKIL G PE + + + L+ +LL D ++R G+L+ G
Sbjct: 270 MLAGYPPFYDPNPILIYEKILAGNLVFPEEIDPLSRDLISSLLTADRSRRLGNLRGGAND 329
Query: 188 ALEYP 192
+P
Sbjct: 330 VKNHP 334
>UniRef50_Q8NIL1 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=6; Fungi|Rep: CAMP-dependent protein kinase
catalytic subunit - Cryptococcus neoformans var.
neoformans
Length = 516
Score = 209 bits (511), Expect = 1e-52
Identities = 91/181 (50%), Positives = 136/181 (75%), Gaps = 2/181 (1%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D +Y ++ + AGGEL++L++K F +++FYAA++ LAL+YLH +++RDLK
Sbjct: 270 TFQDVNNLYMVMDFVAGGELFSLLRKSQRFPNSVAKFYAAEVALALDYLHSLDIIYRDLK 329
Query: 66 PENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
PEN+L+ + G++K+ +FGF K + TWTLCGTP+YLAPE++ SKGY+ VDW+ALGVLI
Sbjct: 330 PENLLLGADGHVKVTNFGFAKYVPDITWTLCGTPDYLAPEVVQSKGYNKSVDWYALGVLI 389
Query: 126 YEMIAAFPPFYSSE--PIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKA 183
+EM+A +PPF++ + P+KLYEKI+ G+ + P + K L+KNLL D TKRYG+L+A
Sbjct: 390 FEMLAGYPPFFTEDGNPMKLYEKIIAGKVRYPTYFDALAKELLKNLLIGDLTKRYGNLRA 449
Query: 184 G 184
G
Sbjct: 450 G 450
>UniRef50_UPI000155CDCE Cluster: PREDICTED: similar to protein
kinase; n=2; Mammalia|Rep: PREDICTED: similar to protein
kinase - Ornithorhynchus anatinus
Length = 450
Score = 209 bits (510), Expect = 2e-52
Identities = 87/182 (47%), Positives = 127/182 (69%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L +T D ++Y ++ Y GGEL++ ++ +G F+ FY+ +++ A+EY+H +V+R
Sbjct: 204 LYWTYHDERFLYMLMEYVPGGELFSYLRNMGRFNNSTGLFYSTEIICAIEYIHSKEIVYR 263
Query: 63 DLKPENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALG 122
DLKPEN+L+ G+IKL DFGF K + +TWTLCGTPEYLAPE+I SKG+ VDWWALG
Sbjct: 264 DLKPENILLDKEGHIKLTDFGFAKKLVDKTWTLCGTPEYLAPEVIQSKGHGRAVDWWALG 323
Query: 123 VLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLK 182
+LI+EM++ FPPF+ P +Y+KIL G+ P ++ K L+K LL VD T+R G++K
Sbjct: 324 ILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDLYVKDLIKKLLVVDRTRRLGNMK 383
Query: 183 AG 184
G
Sbjct: 384 NG 385
>UniRef50_P34099 Cluster: cAMP-dependent protein kinase catalytic
subunit; n=23; Eukaryota|Rep: cAMP-dependent protein
kinase catalytic subunit - Dictyostelium discoideum
(Slime mold)
Length = 648
Score = 208 bits (508), Expect = 3e-52
Identities = 98/204 (48%), Positives = 136/204 (66%), Gaps = 3/204 (1%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
+D +Y + Y AGGE++T ++K FS ++FYAA++VLALE+LH ++V+RDLKPE
Sbjct: 404 QDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQNIVYRDLKPE 463
Query: 68 NVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
N+L+ + G+IK+ DFGF K ++ RT+TLCGTPEYLAPE+I SKG+ VDWWALG+LI+E
Sbjct: 464 NLLIDNQGHIKITDFGFAKRVEDRTFTLCGTPEYLAPEIIQSKGHGKAVDWWALGILIFE 523
Query: 128 MIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFR 187
M+A +PPFY + +Y KIL G+ P K L+K LL D T+R G+LK G
Sbjct: 524 MLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDLIKRLLTADRTRRLGALKDG--- 580
Query: 188 ALEYPAEMAKQDFHRERVLSERWN 211
AL+ D + ER+ R N
Sbjct: 581 ALDVKNHRWFSDINWERLYQRRDN 604
>UniRef50_O44020 Cluster: PKA protein; n=13; Eukaryota|Rep: PKA
protein - Plasmodium falciparum
Length = 342
Score = 207 bits (506), Expect = 5e-52
Identities = 90/192 (46%), Positives = 131/192 (68%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L + KD+ Y+Y +L + GGE +T +++ F + FYAAQ+VL EYL ++V
Sbjct: 96 VNLHGSFKDDSYLYLVLEFVIGGEFFTFLRRNKRFPNDVGCFYAAQIVLIFEYLQSLNIV 155
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
+RD KPEN+L+ G+IK+ DFGF KI+++RT+TLCGTPEY APE++L+ G+ DWW
Sbjct: 156 YRDFKPENLLLDKDGFIKMTDFGFAKIVETRTYTLCGTPEYTAPEILLNVGHGKAADWWT 215
Query: 121 LGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
LG+ IYE++ PPFY++EP+ +Y+KIL G P+ + CK L+K LL D TKRYG+
Sbjct: 216 LGIFIYEILVGCPPFYANEPLLIYQKILEGIIYFPKFLDNNCKHLMKKLLSHDLTKRYGN 275
Query: 181 LKAGVFRALEYP 192
LK G E+P
Sbjct: 276 LKKGPQNVKEHP 287
>UniRef50_Q9BMY6 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=1; Toxoplasma gondii|Rep: CAMP-dependent
protein kinase catalytic subunit - Toxoplasma gondii
Length = 394
Score = 202 bits (494), Expect = 1e-50
Identities = 85/177 (48%), Positives = 121/177 (68%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
+D ++ ++ Y GGEL++ +++ ++ YAA++ LA +YLH +V+RDLKPE
Sbjct: 152 QDEKRLFILMEYVNGGELFSHLRRRNCIPTDQARLYAAEITLAFQYLHQRHIVYRDLKPE 211
Query: 68 NVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
N+L+ S G+IK+ DFGF K++K RTWTLCGT EYLAPE I +G+ PVDWWALG+L++E
Sbjct: 212 NLLIDSQGHIKITDFGFAKVVKDRTWTLCGTHEYLAPESITRRGHGLPVDWWALGILLFE 271
Query: 128 MIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAG 184
M+A PPF P+ +Y KI+ G+ + P + K+LVK LL DP KRYG LK G
Sbjct: 272 MLAGHPPFVDENPLGIYRKIIAGKIEFPRSFDYAAKSLVKRLLTHDPLKRYGCLKDG 328
>UniRef50_Q4UE84 Cluster: CAMP-dependent protein kinase catalytic
subunit, putative; n=2; Theileria|Rep: CAMP-dependent
protein kinase catalytic subunit, putative - Theileria
annulata
Length = 353
Score = 200 bits (489), Expect = 6e-50
Identities = 85/178 (47%), Positives = 122/178 (68%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KDN Y+Y ++ Y + G+ +T ++K + FYAAQ+ EYLH ++++RDLKPE
Sbjct: 117 KDNHYLYLVMEYVSSGDFFTYLRKENYLESHDAMFYAAQVTAMFEYLHDNNIIYRDLKPE 176
Query: 68 NVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
N+L+ GY+KL DFGF K+++ RT+TLCGTPEY++PE+IL GY VDWW LG+LIYE
Sbjct: 177 NLLLCFDGYLKLTDFGFAKVVEFRTYTLCGTPEYMSPEIILHLGYGKAVDWWTLGILIYE 236
Query: 128 MIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGV 185
M+A +PPFY S P LY+KIL + K P + + K L LL +P++R+G+L G+
Sbjct: 237 MLAGYPPFYDSNPQSLYDKILKCKLKFPIHYDEDAKYLTSRLLVTEPSQRFGNLHKGI 294
>UniRef50_P40376 Cluster: cAMP-dependent protein kinase catalytic
subunit; n=1; Schizosaccharomyces pombe|Rep:
cAMP-dependent protein kinase catalytic subunit -
Schizosaccharomyces pombe (Fission yeast)
Length = 512
Score = 197 bits (480), Expect = 7e-49
Identities = 88/188 (46%), Positives = 130/188 (69%), Gaps = 1/188 (0%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D ++ ++ + GGEL++L++K F E +++FYAA+++LAL+YLHH +V+RDLK
Sbjct: 267 TFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLHHNQIVYRDLK 326
Query: 66 PENVLVSSSGYIKLADFGFCKIIK-SRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVL 124
PEN+L+ G++K+ DFGF K + S TLCGTP+YLAPE+I K Y+ DWW+LG+L
Sbjct: 327 PENLLLDRFGHLKIVDFGFAKRVSTSNCCTLCGTPDYLAPEIISLKPYNKAADWWSLGIL 386
Query: 125 IYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAG 184
I+EM+A +PPFYS P+KLYE IL G+ P + L+ +LL+ D T RYG+LK G
Sbjct: 387 IFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHLLQRDITCRYGNLKDG 446
Query: 185 VFRALEYP 192
+ +P
Sbjct: 447 SMDIIMHP 454
>UniRef50_Q9VA47 Cluster: CG12069-PA; n=3; Sophophora|Rep:
CG12069-PA - Drosophila melanogaster (Fruit fly)
Length = 356
Score = 196 bits (478), Expect = 1e-48
Identities = 88/179 (49%), Positives = 126/179 (70%), Gaps = 2/179 (1%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KD +Y +LP GGEL+T +K+ F+E ++FYAAQ+ LALEYLHHCS+++RDLKPE
Sbjct: 115 KDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPE 174
Query: 68 NVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
N+++ +GY+K+ DFGF K +++RT TLCGTPEYL PE+I SK Y VDWWA GVL++E
Sbjct: 175 NIMMDKNGYLKVTDFGFAKKVETRTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFE 234
Query: 128 MIAAFPPF--YSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAG 184
+A PF ++ + + +Y KI +K P + + LV +LL+VD +KR+G+L G
Sbjct: 235 FVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLING 293
>UniRef50_Q4SLK1 Cluster: Chromosome 15 SCAF14556, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 15
SCAF14556, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 395
Score = 195 bits (475), Expect = 3e-48
Identities = 103/213 (48%), Positives = 142/213 (66%), Gaps = 29/213 (13%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYL------ 54
+ L++ KDN +Y ++ Y GGE+++ ++++G FSEP ++FYAAQ+VL EYL
Sbjct: 123 VKLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLI 182
Query: 55 ------------HHC------SVVH---RDLKPENVL-VSSSGYIKLADFGFCKIIKSRT 92
HH S H R L+P V V SG+ ++ DFGF K +K RT
Sbjct: 183 YRDLKPENLLIDHHGYIQVSRSARHACGRLLRPVPVAHVWLSGF-QVTDFGFAKRVKGRT 241
Query: 93 WTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQF 152
WTLCGTPEYLAPE+ILSKGY+ VDWWALGVLIYEM A +PPF++ +PI++YEKI++G+
Sbjct: 242 WTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV 301
Query: 153 KTPENMTQVCKALVKNLLEVDPTKRYGSLKAGV 185
+ P + + K L++NLL+VD TKRYG+LK GV
Sbjct: 302 RFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGV 334
>UniRef50_P05986 Cluster: cAMP-dependent protein kinase type 3;
n=56; Dikarya|Rep: cAMP-dependent protein kinase type 3
- Saccharomyces cerevisiae (Baker's yeast)
Length = 398
Score = 193 bits (470), Expect = 1e-47
Identities = 83/179 (46%), Positives = 126/179 (70%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D+ V+ ++ Y GGEL++L++K F P+++FYAA++ LALEYLH +++RDLK
Sbjct: 154 TFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLK 213
Query: 66 PENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
PEN+L+ +G+IK+ DFGF K + T+TLCGTP+Y+APE++ +K Y+ VDWW+ GVLI
Sbjct: 214 PENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLI 273
Query: 126 YEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAG 184
YEM+A + PFY+S +K YE IL + K P + L+K L+ D ++R G+L+ G
Sbjct: 274 YEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNG 332
>UniRef50_Q20541 Cluster: Cyclic AMP-dependent protein kinase,
catalytic subunit; n=5; Caenorhabditis|Rep: Cyclic
AMP-dependent protein kinase, catalytic subunit -
Caenorhabditis elegans
Length = 371
Score = 192 bits (469), Expect = 2e-47
Identities = 82/177 (46%), Positives = 124/177 (70%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KD+ ++Y I+ + GGE+++ ++ FS +++FYA+++V ALEY+H +V+RDLKPE
Sbjct: 131 KDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPE 190
Query: 68 NVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
N+++S G+IK+ADFGF K ++ RT+T+CGTP+YLAPE + G++ VDWWALG+LIYE
Sbjct: 191 NLMLSKEGHIKMADFGFAKELRDRTYTICGTPDYLAPESLARTGHNKGVDWWALGILIYE 250
Query: 128 MIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAG 184
M+ PPF ++Y+ I+ + K P + K LVK LLEVD T+R G +K G
Sbjct: 251 MMVGKPPFRGKTTSEIYDAIIEHKLKFPRSFNLAAKDLVKKLLEVDRTQRIGCMKNG 307
>UniRef50_A6QTK8 Cluster: Serine/threonine-protein kinase PRKX; n=1;
Ajellomyces capsulatus NAm1|Rep:
Serine/threonine-protein kinase PRKX - Ajellomyces
capsulatus NAm1
Length = 412
Score = 191 bits (465), Expect = 5e-47
Identities = 86/188 (45%), Positives = 127/188 (67%), Gaps = 2/188 (1%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHC-SVVHRDL 64
T D++ +Y +L Y GGE++T +++ F +QFYAA++VL LE+LH + +RDL
Sbjct: 162 TFTDDLSLYMLLEYCPGGEIFTFLRRARRFDVSTAQFYAAEIVLILEFLHDVHGIAYRDL 221
Query: 65 KPENVLVSSSGYIKLADFGFCKIIKSR-TWTLCGTPEYLAPELILSKGYSFPVDWWALGV 123
KPEN+L+ + G++KL DFGF K I SR T+TLCGTPEYLAPE+I + G+ VDWWALGV
Sbjct: 222 KPENILLDADGHLKLVDFGFAKEIWSRETYTLCGTPEYLAPEVIHNSGHGLAVDWWALGV 281
Query: 124 LIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKA 183
LIYE I PPF+ P+++Y++I+ G + P NM + +V L + +P++R G +K
Sbjct: 282 LIYEFIVGQPPFWDPNPMRIYKQIVDGVLRFPANMPPAAQDIVSRLCQTNPSERLGHIKG 341
Query: 184 GVFRALEY 191
G R ++
Sbjct: 342 GSARVKQH 349
>UniRef50_Q6CW38 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome B of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome B of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 455
Score = 190 bits (463), Expect = 8e-47
Identities = 83/179 (46%), Positives = 123/179 (68%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D+ ++ I+ Y GGEL++L++K F P+++FYAA++ LALEYLH +++RDLK
Sbjct: 211 TFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKGIIYRDLK 270
Query: 66 PENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
PEN+L+ +G+IKL DFGF K + T+TLCGTP+Y+APE++ +K Y+ VDWW+ GVLI
Sbjct: 271 PENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLI 330
Query: 126 YEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAG 184
YEM+A + PFY S IK YE IL + P + L+ L+ D ++R G+L+ G
Sbjct: 331 YEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQRLGNLQNG 389
>UniRef50_Q2U6J7 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=8; Eurotiomycetidae|Rep: CAMP-dependent
protein kinase catalytic subunit - Aspergillus oryzae
Length = 396
Score = 190 bits (463), Expect = 8e-47
Identities = 80/186 (43%), Positives = 129/186 (69%), Gaps = 2/186 (1%)
Query: 9 DNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCS-VVHRDLKPE 67
D+ +Y +L Y GGE+++ +++ F+E ++FYAA++ L +E+LH +V+RDLKPE
Sbjct: 150 DDQSLYMLLDYCPGGEIFSYLRRARRFNENTAKFYAAEITLTIEFLHDVEGIVYRDLKPE 209
Query: 68 NVLVSSSGYIKLADFGFCKIIKSR-TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIY 126
N+L+ + G+I+L DFGF K + +R T+TLCGTPEYLAPE+I + G+ VDWWALG+LIY
Sbjct: 210 NILLDAEGHIRLVDFGFAKKVDNRETYTLCGTPEYLAPEVIHNSGHGLAVDWWALGILIY 269
Query: 127 EMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVF 186
E + PPF+ P+++YE+I+ G+ + P+NM+ + ++ L + +PT+R G + G
Sbjct: 270 EFLVGQPPFWDQNPMRIYEQIVEGRIRFPQNMSPAAQNIISLLCKTNPTERLGYISGGSA 329
Query: 187 RALEYP 192
R +P
Sbjct: 330 RVKSHP 335
>UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14
SCAF15003, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 621
Score = 189 bits (461), Expect = 1e-46
Identities = 85/185 (45%), Positives = 128/185 (69%), Gaps = 2/185 (1%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L T KD YVY I+ + GGE++T +K++G F EP++ F AA +V A YLH S+++R
Sbjct: 383 LHATFKDTRYVYMIMEFCGGGEIWTKLKEVGRFDEPMAVFCAACVVEAFAYLHKKSIMYR 442
Query: 63 DLKPENVLVSSSGYIKLADFGFCK--IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
DLKPEN+++ + GY+KL DFGF K + +T++ GTPEY+APE+I ++G+ F VD+W+
Sbjct: 443 DLKPENLMLDAKGYVKLVDFGFAKEMVRAEKTYSFVGTPEYMAPEIIKNQGHDFAVDFWS 502
Query: 121 LGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
LG+LI+E++A PPF SSEP K+Y KIL G K P +++ K+++ L P +R G+
Sbjct: 503 LGILIFELLAGSPPFSSSEPQKIYAKILDGVLKYPPYLSEASKSIISKLCRPRPGQRLGN 562
Query: 181 LKAGV 185
K G+
Sbjct: 563 TKNGI 567
>UniRef50_UPI00006CB393 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 538
Score = 188 bits (459), Expect = 3e-46
Identities = 82/138 (59%), Positives = 105/138 (76%)
Query: 48 VLALEYLHHCSVVHRDLKPENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELI 107
V EYLH+ ++V+RDLKPEN+L+ S GY+KL DFGF K SRT+TLCGTPEYLAPE++
Sbjct: 339 VSMFEYLHNKNIVYRDLKPENILIGSDGYLKLTDFGFAKYCDSRTYTLCGTPEYLAPEIL 398
Query: 108 LSKGYSFPVDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVK 167
L+KG+ PVDWW LG+LIYEM+A PF +P+ +Y+KIL G+ K P N + K+LVK
Sbjct: 399 LNKGHGKPVDWWCLGILIYEMLAGIDPFNDEDPMAIYQKILKGKVKFPRNFDKNAKSLVK 458
Query: 168 NLLEVDPTKRYGSLKAGV 185
+LL D TKRYG+LK GV
Sbjct: 459 HLLVADLTKRYGNLKGGV 476
Score = 46.8 bits (106), Expect = 0.002
Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 5/67 (7%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVL----ALEYLHHCS 58
+ FT +D+ ++YF+L Y AGGEL+T ++ G P + FYAAQ+ + L Y +H
Sbjct: 215 IGFT-QDDRFLYFVLEYVAGGELFTYLRNKGKLDNPEALFYAAQVYIFVCDLLSYDNHFE 273
Query: 59 VVHRDLK 65
+LK
Sbjct: 274 TQQINLK 280
>UniRef50_Q22DD1 Cluster: Protein kinase domain containing protein;
n=7; Oligohymenophorea|Rep: Protein kinase domain
containing protein - Tetrahymena thermophila SB210
Length = 531
Score = 188 bits (459), Expect = 3e-46
Identities = 86/182 (47%), Positives = 124/182 (68%), Gaps = 3/182 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L T +D +Y+Y + + +GGE+++ ++K G FS +S FY ++ LAL+YLH ++V
Sbjct: 273 VELKGTFQDEIYIYMLFEFVSGGEIFSRLRKEGRFSNDISLFYITEIYLALQYLHSQNIV 332
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKS-RTWTLCGTPEYLAPELI--LSKGYSFPVD 117
+RDLKPEN+L+ G++K+ADFGF KI+ S RT+TLCGTPEYLAPE+I GY VD
Sbjct: 333 YRDLKPENLLIDKEGHVKIADFGFAKIMDSARTYTLCGTPEYLAPEIIQGAKTGYGKSVD 392
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WWALGVLI+EM++ PPFY +P+ +Y+KI+ PE + K LV+ LL + R
Sbjct: 393 WWALGVLIFEMLSGHPPFYDCDPMGIYQKIVNSVINFPEFFSLRAKDLVRKLLNPNIESR 452
Query: 178 YG 179
G
Sbjct: 453 LG 454
>UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23;
Euteleostomi|Rep: cGMP-dependent protein kinase 2 - Homo
sapiens (Human)
Length = 762
Score = 185 bits (451), Expect = 2e-45
Identities = 84/184 (45%), Positives = 124/184 (67%), Gaps = 4/184 (2%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T KDN YVY +L GGEL+++++ G F EP S+F A + A +YLH +++RDLK
Sbjct: 519 TFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLK 578
Query: 66 PENVLVSSSGYIKLADFGFCKIIKS--RTWTLCGTPEYLAPELILSKGYSFPVDWWALGV 123
PEN+++ + GY+KL DFGF K I S +TWT CGTPEY+APE+IL+KG+ F VD+W+LG+
Sbjct: 579 PENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGI 638
Query: 124 LIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPTKRYGSL 181
L+YE++ PPF + + Y IL G + P +T+ + L++ L +PT+R G+L
Sbjct: 639 LVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNL 698
Query: 182 KAGV 185
K G+
Sbjct: 699 KNGI 702
>UniRef50_P21901 Cluster: Spermatozoon-associated protein kinase;
n=1; Aplysia californica|Rep: Spermatozoon-associated
protein kinase - Aplysia californica (California sea
hare)
Length = 351
Score = 185 bits (451), Expect = 2e-45
Identities = 94/244 (38%), Positives = 150/244 (61%), Gaps = 7/244 (2%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KD +Y ++ + GGEL+ L++K G E FYAAQ+ +AL+YLH+CS+++RDLKPE
Sbjct: 112 KDTTNLYMVMEFVNGGELFHLLRKKGRLPEYWCTFYAAQVTMALQYLHNCSLLYRDLKPE 171
Query: 68 NVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
N+L+ GY+K+ DFGF + ++ TWTLCGTP+YLAPE+IL++ Y+ LG+LIYE
Sbjct: 172 NILLDHLGYLKVTDFGFDRRVQGHTWTLCGTPQYLAPEMILNRSYASQWTTGGLGILIYE 231
Query: 128 MIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFR 187
+ A F PF P+KLYE I+ + P + L+ N+++VD T+R+G+L+ G
Sbjct: 232 LNAGFVPFDHKVPLKLYELIVECRLTFPSFFKPTLRDLLTNIIQVDVTRRFGNLRNGALD 291
Query: 188 ALEYPAEMAKQDFHRERVLSER--WNLIRFVAQWTNGTEYFNGVEELLSHHLAIYEKVLE 245
+ +P DF + + +E+ W + QW + T + EE +S ++ ++K +
Sbjct: 292 IINHP-WFKDTDFRKILMKAEKAPW-VPNLKGQWIHQT-FDKWTEESIS--ISKHDKYPD 346
Query: 246 EASS 249
E S+
Sbjct: 347 EFSN 350
>UniRef50_Q17941 Cluster: Serine/threonine-protein kinase akt-1;
n=6; Caenorhabditis|Rep: Serine/threonine-protein kinase
akt-1 - Caenorhabditis elegans
Length = 541
Score = 184 bits (447), Expect = 7e-45
Identities = 87/207 (42%), Positives = 130/207 (62%), Gaps = 11/207 (5%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L ++ ++ Y+ F++ + GGEL+T ++K G FSEP ++FY A++VLAL YLH C +V+R
Sbjct: 256 LKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGYLHRCDIVYR 315
Query: 63 DLKPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWW 119
D+K EN+L+ G+IK+ADFG CK +T T CGTPEYLAPE++ Y VDWW
Sbjct: 316 DMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAPEVLDDHDYGRCVDWW 375
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
+GV++YEM+ PFYS + KL+E I+ G + P ++Q + L+ LL DPT+R G
Sbjct: 376 GVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEARTLLTGLLVKDPTQRLG 435
Query: 180 S--------LKAGVFRALEYPAEMAKQ 198
+A FR +++ A K+
Sbjct: 436 GGPEDALEICRADFFRTVDWEATYRKE 462
>UniRef50_Q33DX3 Cluster: Putative cyclic AMP-dependent protein
kinase catalytic subunit; n=1; Schizophyllum
commune|Rep: Putative cyclic AMP-dependent protein
kinase catalytic subunit - Schizophyllum commune
(Bracket fungus)
Length = 427
Score = 182 bits (444), Expect = 2e-44
Identities = 84/190 (44%), Positives = 129/190 (67%), Gaps = 5/190 (2%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
+D +Y ++ + GGEL+ L+++ F EP+++FYAA++ LAL YLH ++++RDLKPE
Sbjct: 169 QDGNNLYMVMDFVPGGELFNLLRRSIRFPEPVAKFYAAEVSLALRYLHSNNIIYRDLKPE 228
Query: 68 NVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
N+L+++ G+IK+ADFGF KI+ + +TLCGTP+YLAPE+I Y+ VDW+ALGVL YE
Sbjct: 229 NILLNADGHIKVADFGFAKIVDTVAYTLCGTPDYLAPEIIWGGRYNKSVDWYALGVLCYE 288
Query: 128 MIAAFPPFYSSE--PIKLYEKILTGQFKTP---ENMTQVCKALVKNLLEVDPTKRYGSLK 182
M++ PPF++ + P LY KI G P N T L++ L+E +P+KRYG+++
Sbjct: 289 MLSGLPPFHTPDGNPQTLYAKIREGPTSLPWNSPNFTLYSIDLIRRLMEGEPSKRYGNMR 348
Query: 183 AGVFRALEYP 192
G +P
Sbjct: 349 HGAGDVFAHP 358
>UniRef50_Q4N4B2 Cluster: CAMP-dependent protein kinase catalytic
subunit, putative; n=2; Theileria|Rep: CAMP-dependent
protein kinase catalytic subunit, putative - Theileria
parva
Length = 511
Score = 181 bits (440), Expect = 5e-44
Identities = 79/174 (45%), Positives = 122/174 (70%), Gaps = 1/174 (0%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
+D + +YFIL + GGEL+T ++++ F ++FYA+Q++LAL+YLH +V+RDLKPE
Sbjct: 272 QDTLNLYFILEFVPGGELFTYLRRMHTFPPEYTRFYASQVLLALDYLHMNKLVYRDLKPE 331
Query: 68 NVLVSSSGYIKLADFGFCKIIKS-RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIY 126
N+L+ GYI+L DFGF K ++S +T+T+CGT +YLAPE+ L KG+ F D+++ GV +Y
Sbjct: 332 NILLDIMGYIRLVDFGFAKRLESGKTYTVCGTCDYLAPEIFLKKGHDFRADFYSFGVFLY 391
Query: 127 EMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
E++ PPFYS+ P K Y+ L + + V + ++KNLL VDP+KR G+
Sbjct: 392 ELLTGVPPFYSNSPQKTYKLALNNEVAFGRKVNNVSRDIIKNLLRVDPSKRLGN 445
>UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate
protein kinase, cGMP-dependent, type I; n=3; Danio
rerio|Rep: Novel protein similar to vertebrate protein
kinase, cGMP-dependent, type I - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 570
Score = 180 bits (439), Expect = 7e-44
Identities = 80/180 (44%), Positives = 121/180 (67%), Gaps = 2/180 (1%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KD+ YVY I+ + GGE++T +K+ G F E ++ F A +V A YLH+ +++RDLKPE
Sbjct: 331 KDSRYVYMIMEFCPGGEIWTKLKEAGRFEEKIAVFITACVVEAYAYLHNKGILYRDLKPE 390
Query: 68 NVLVSSSGYIKLADFGFCKIIK--SRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
N+++ S GY+KL DFGF K + +T++ CGTPEY++PE+I ++G+ D+W+LGVLI
Sbjct: 391 NLMLDSKGYVKLVDFGFAKELSRGEKTYSFCGTPEYISPEIIQNQGHDIAADFWSLGVLI 450
Query: 126 YEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGV 185
YE++ PPF SSEP K+Y KIL G P M + K+++ L + P +R G+ K G+
Sbjct: 451 YELLVGSPPFSSSEPQKIYAKILDGVLNFPSYMGEGAKSIISKLCRLRPGQRLGNTKNGI 510
>UniRef50_A7AWS2 Cluster: cAMP-dependent protein kinase; n=1;
Babesia bovis|Rep: cAMP-dependent protein kinase -
Babesia bovis
Length = 416
Score = 179 bits (435), Expect = 2e-43
Identities = 75/172 (43%), Positives = 116/172 (67%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
+D++ VY +L Y +GGEL++ I K G +++FY AQ +LA+++LH +V+RDLKPE
Sbjct: 176 QDDINVYILLEYVSGGELFSYIYKYGALGHTVARFYTAQAILAIDFLHFKGIVYRDLKPE 235
Query: 68 NVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
N+L+ G+I+L DFGF K +K +T+T+CGT +YLAPE+ L G+ DWW+LGVL+YE
Sbjct: 236 NMLLDQDGHIRLVDFGFAKEVKHKTYTVCGTHDYLAPEIFLRCGHGIEADWWSLGVLVYE 295
Query: 128 MIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
++ PPF++S+P Y+ L + P ++ K ++ LL V+P KR G
Sbjct: 296 ILTGVPPFHASDPSATYDLALANHIRFPLSVRVEVKDFIRRLLVVNPRKRLG 347
>UniRef50_Q86ZN6 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=7; Pezizomycotina|Rep: CAMP-dependent protein
kinase catalytic subunit - Magnaporthe grisea (Rice
blast fungus) (Pyricularia grisea)
Length = 408
Score = 179 bits (435), Expect = 2e-43
Identities = 84/198 (42%), Positives = 129/198 (65%), Gaps = 14/198 (7%)
Query: 9 DNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCS--VVHRDLKP 66
D+ ++Y +L Y GGEL++ ++K F E +++FYAA++VL LEYLH V +RDLKP
Sbjct: 151 DHDFLYIVLDYVPGGELFSYLRKYRRFDEDMARFYAAEIVLVLEYLHEAQDGVAYRDLKP 210
Query: 67 ENVLVSSSGYIKLADFGFCKIIKSR----------TWTLCGTPEYLAPELILSKGYSFPV 116
EN+L+ G+IKL DFGF K + R T+TLCGTPEYLAPE+I +KG++ V
Sbjct: 211 ENLLLDGQGHIKLVDFGFAKRLGGRRDGDNSGTQETYTLCGTPEYLAPEVIHNKGHTTAV 270
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN--MTQVCKALVKNLLEVDP 174
DWWALG+LIYE + +PPF+ PI++Y++I+ P++ ++ + +++ VD
Sbjct: 271 DWWALGILIYEFLTGYPPFWHQNPIEIYKQIVEKPVVFPQDPPISPNAQDIIRQFCTVDR 330
Query: 175 TKRYGSLKAGVFRALEYP 192
++R G++ G R E+P
Sbjct: 331 SRRLGNISGGAARVKEHP 348
>UniRef50_P16911 Cluster: Protein kinase DC1; n=5; Sophophora|Rep:
Protein kinase DC1 - Drosophila melanogaster (Fruit fly)
Length = 376
Score = 178 bits (434), Expect = 3e-43
Identities = 80/168 (47%), Positives = 117/168 (69%), Gaps = 2/168 (1%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
Y+Y ILP GGEL++ +++ F+E ++FYAAQ+ LALEY+H +++RDLKPEN+L+
Sbjct: 117 YLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILL 176
Query: 72 SSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAA 131
GYIK+ DFGF K + RT TLCGTPEYLAPE++ + Y+ VDWWA G+L+YE +A
Sbjct: 177 DQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAG 236
Query: 132 FPPF--YSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
PF ++ + I +Y KI +K P T ++LV++L++VD +KR
Sbjct: 237 RSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKR 284
>UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 17
SCAF14563, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 726
Score = 177 bits (431), Expect = 6e-43
Identities = 80/184 (43%), Positives = 121/184 (65%), Gaps = 4/184 (2%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T KD+ Y+Y ++ GGEL+T+++ G F + ++FY A +V A YLH +++RDLK
Sbjct: 482 TFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLK 541
Query: 66 PENVLVSSSGYIKLADFGFCKII--KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGV 123
PEN+++ GY KL DFGF K I +TWT CGTPEY+APE+IL+KG+ D+W+LG+
Sbjct: 542 PENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGI 601
Query: 124 LIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPTKRYGSL 181
L++E++ PPF +P+K Y IL G + P+ +T+ L+K L +P++R G+L
Sbjct: 602 LMFELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAANLIKKLCRDNPSERLGNL 661
Query: 182 KAGV 185
K GV
Sbjct: 662 KNGV 665
>UniRef50_Q2PJ68 Cluster: Putative uncharacterized protein sgk-1;
n=3; Caenorhabditis|Rep: Putative uncharacterized
protein sgk-1 - Caenorhabditis elegans
Length = 463
Score = 177 bits (430), Expect = 8e-43
Identities = 83/182 (45%), Positives = 121/182 (66%), Gaps = 3/182 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL F+ ++ +YF+L + GGEL++ +++ FSE S+FYAA++ AL YLH +++
Sbjct: 197 VSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLHEKNII 256
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK--IIKSRTW-TLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L+ GY+ L DFG CK + S+T T CGTPEYLAPE+IL K Y VD
Sbjct: 257 YRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKPYDKTVD 316
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW LG ++YEMI PPFYS + ++Y+KI+ + N++ C L+ LL+ D +KR
Sbjct: 317 WWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLLQKDRSKR 376
Query: 178 YG 179
G
Sbjct: 377 LG 378
>UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta
isozyme; n=49; Bilateria|Rep: cGMP-dependent protein
kinase 1, beta isozyme - Homo sapiens (Human)
Length = 686
Score = 177 bits (430), Expect = 8e-43
Identities = 80/184 (43%), Positives = 120/184 (65%), Gaps = 4/184 (2%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T KD+ Y+Y ++ GGEL+T+++ G F + ++FY A +V A YLH +++RDLK
Sbjct: 442 TFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLK 501
Query: 66 PENVLVSSSGYIKLADFGFCKII--KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGV 123
PEN+++ GY KL DFGF K I +TWT CGTPEY+APE+IL+KG+ D+W+LG+
Sbjct: 502 PENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGI 561
Query: 124 LIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPTKRYGSL 181
L+YE++ PPF +P+K Y IL G + P+ + + L+K L +P++R G+L
Sbjct: 562 LMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNL 621
Query: 182 KAGV 185
K GV
Sbjct: 622 KNGV 625
>UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=1;
Hydra oligactis|Rep: Cyclic GMP-dependent protein kinase
- Hydra oligactis (Hydra)
Length = 742
Score = 176 bits (429), Expect = 1e-42
Identities = 84/182 (46%), Positives = 120/182 (65%), Gaps = 4/182 (2%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KD+ YVY +L GGEL+T+++ F E +FY A +V A EY+H +++RDLKPE
Sbjct: 501 KDDRYVYLLLEVCLGGELWTILRDRDYFEEAACRFYIACVVEAFEYIHKRGIIYRDLKPE 560
Query: 68 NVLVSSSGYIKLADFGFCKIIKS--RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
N+L+ S GYIK+ DFGF K I S +TWT CGTPEY+ PE+IL+KG+ D+W+LG+LI
Sbjct: 561 NLLMDSQGYIKIVDFGFAKKISSGTKTWTFCGTPEYVPPEIILNKGHDSSADYWSLGILI 620
Query: 126 YEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPTKRYGSLKA 183
YE++ PPF SS+P+ Y IL G + +T+ + L+K L + +P +R G+ K
Sbjct: 621 YELMVGNPPFSSSDPMSTYNIILRGIEVLEFSNLVTKNAQNLIKRLCKENPMERLGNQKD 680
Query: 184 GV 185
GV
Sbjct: 681 GV 682
>UniRef50_A0CMB4 Cluster: Chromosome undetermined scaffold_21, whole
genome shotgun sequence; n=2; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_21, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 333
Score = 175 bits (427), Expect = 2e-42
Identities = 79/187 (42%), Positives = 126/187 (67%), Gaps = 3/187 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ ++ +YF+L Y GGEL+ L++K +E +FY Q++LA+EYLH +++
Sbjct: 75 IKLAFSFQNERKLYFVLEYCPGGELFNLLQKKKKLTEDQCRFYVCQMILAIEYLHENNII 134
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI-IKSR--TWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPENV++ + GYI++ DFG K +K +++CGTPEYLAPE+++ +G+ PVD
Sbjct: 135 YRDLKPENVILDADGYIRITDFGLSKKNVKQDKDAFSVCGTPEYLAPEILMKQGHGKPVD 194
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW LG +I+EMI PP+YS++ +L+E+I K P+N++ + K L++ L + P KR
Sbjct: 195 WWTLGCIIFEMITGMPPYYSNQRGELFEQIKYQFPKYPQNLSPILKNLLEGLFQKQPEKR 254
Query: 178 YGSLKAG 184
G AG
Sbjct: 255 LGYNGAG 261
>UniRef50_P28178 Cluster: Protein kinase 2; n=2; Dictyostelium
discoideum|Rep: Protein kinase 2 - Dictyostelium
discoideum (Slime mold)
Length = 479
Score = 175 bits (427), Expect = 2e-42
Identities = 83/182 (45%), Positives = 120/182 (65%), Gaps = 4/182 (2%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
F KD +Y+ +L + GGEL+ +K+ G FSEP + YAA++V AL++LH +V+RDL
Sbjct: 220 FQTKDKLYM--VLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQDIVYRDL 277
Query: 65 KPENVLVSSSGYIKLADFGFCKIIKSR--TWTLCGTPEYLAPELILSKGYSFPVDWWALG 122
KPEN+L+ S G+I + DFG K I++ T+T CGTPEYLAPE++ G+ VDWW+LG
Sbjct: 278 KPENILLDSEGHICITDFGLSKKIETTDGTFTFCGTPEYLAPEVLNGHGHGCAVDWWSLG 337
Query: 123 VLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLK 182
L+YEM+ PPFYS +Y+KIL G+ K P ++ K+L++ LL + KR G+
Sbjct: 338 TLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSLLEGLLTREVDKRLGTKG 397
Query: 183 AG 184
G
Sbjct: 398 GG 399
>UniRef50_Q9P7J8 Cluster: Serine/threonine-protein kinase gad8; n=4;
Dikarya|Rep: Serine/threonine-protein kinase gad8 -
Schizosaccharomyces pombe (Fission yeast)
Length = 569
Score = 174 bits (424), Expect = 4e-42
Identities = 84/181 (46%), Positives = 117/181 (64%), Gaps = 3/181 (1%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L F+ + +Y +L + GGEL+ +++ G F ++FY A+L++ALE LH +V++R
Sbjct: 293 LKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHEFNVIYR 352
Query: 63 DLKPENVLVSSSGYIKLADFGFCKIIKS---RTWTLCGTPEYLAPELILSKGYSFPVDWW 119
DLKPEN+L+ +G+I L DFG CK+ + RT T CGTPEYLAPEL+L GY+ VDWW
Sbjct: 353 DLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGHGYTKVVDWW 412
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
LGVL+YEMI PPFY ++Y KIL + P+N+ + K L+ LL P KR G
Sbjct: 413 TLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDLLSGLLTRAPEKRLG 472
Query: 180 S 180
S
Sbjct: 473 S 473
>UniRef50_A0BEY5 Cluster: Chromosome undetermined scaffold_103,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_103,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 524
Score = 173 bits (422), Expect = 8e-42
Identities = 81/206 (39%), Positives = 129/206 (62%), Gaps = 6/206 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL++ VYF++ + GGELYT ++K+ F+E + FY++Q++LALEYLH ++
Sbjct: 260 VSLEYAFITQECVYFVMKFMIGGELYTHLQKINKFNEEFALFYSSQVLLALEYLHKQGII 319
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSR--TWTLCGTPEYLAPELILSKGYSFPVDW 118
+RDLKPEN+L+ GY+ L D+G K + T ++ GTPEYLAPE+I +G++F DW
Sbjct: 320 YRDLKPENILMDEKGYVALTDYGLAKFLSKGQVTQSIVGTPEYLAPEVITQQGHAFTADW 379
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPE--NMTQVCKALVKNLLEVDPTK 176
W LG+LIYEM+ PF+S +++ I+ + K P ++T CK+L+ +LL+ P +
Sbjct: 380 WCLGILIYEMLCGKTPFFSENRNQMFRNIVESELKFPSTLHITPECKSLLTSLLKKKPNE 439
Query: 177 RYGSLKAGVFRALEYPAEMAKQDFHR 202
R G+ G ++ A + DF R
Sbjct: 440 RLGN--KGDAEEIKKHAWFKRMDFQR 463
>UniRef50_P12688 Cluster: Serine/threonine-protein kinase YPK1;
n=10; Saccharomycetales|Rep: Serine/threonine-protein
kinase YPK1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 680
Score = 173 bits (420), Expect = 1e-41
Identities = 84/180 (46%), Positives = 116/180 (64%), Gaps = 3/180 (1%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L F+ + +YF+L + GGEL+ ++K G F ++FY A+L+ AL+ LH VV+R
Sbjct: 410 LKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYR 469
Query: 63 DLKPENVLVSSSGYIKLADFGFCKI-IKS--RTWTLCGTPEYLAPELILSKGYSFPVDWW 119
DLKPEN+L+ G+I L DFG CK+ +K +T T CGTPEYLAPEL+L GY+ VDWW
Sbjct: 470 DLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWW 529
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
LGVL+YEM+ PP+Y + K+Y+KIL P+ + K L+ LL DPT+R G
Sbjct: 530 TLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLG 589
>UniRef50_UPI000150A8F4 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 399
Score = 172 bits (419), Expect = 2e-41
Identities = 83/195 (42%), Positives = 122/195 (62%), Gaps = 4/195 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ + + +D ++F+L Y GGELY+L+ +E ++FYAAQLV A+EYLH +++
Sbjct: 105 VKMKYAFQDKQKLFFVLEYCGGGELYSLLSSKKYLNEQQTKFYAAQLVKAIEYLHSHNII 164
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI-IKSRT--WTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L+ GYIKL DFG K+ IK T +LCGTPEYLAPE++ G+ PVD
Sbjct: 165 YRDLKPENILIDKDGYIKLTDFGLSKMDIKHNTEATSLCGTPEYLAPEILEQSGHGKPVD 224
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW LG +I+EM+ PPFY+ +++ I K + K L+ +LLE DP KR
Sbjct: 225 WWTLGNIIWEMMTGLPPFYNENRKEMFHHIKELPLKNHPRIQGDLKNLLHSLLEKDPNKR 284
Query: 178 YGSLKAGVFRALEYP 192
G++ G +++P
Sbjct: 285 LGTID-GAKEIIDHP 298
>UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform a;
n=5; Caenorhabditis elegans|Rep: Egg laying defective
protein 4, isoform a - Caenorhabditis elegans
Length = 780
Score = 170 bits (413), Expect = 1e-40
Identities = 83/185 (44%), Positives = 121/185 (65%), Gaps = 5/185 (2%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D +VY +L GGEL+T ++ G F + ++FY A ++ LEYLH ++V+RDLK
Sbjct: 536 TFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDLK 595
Query: 66 PENVLVSSSGYIKLADFGFCKIIKS--RTWTLCGTPEYLAPELILSKGYSFPVDWWALGV 123
PEN L++++GY+KL DFGF K + S +TWT CGTPEY++PE+IL+KG+ D+WALG+
Sbjct: 596 PENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHDQAADYWALGI 655
Query: 124 LIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTP-ENMTQVCKALVKNLLEVDPTKRYGS 180
I E++ PPF +S+P+K Y IL G + P + + ALVK L +P +R GS
Sbjct: 656 YICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGERLGS 715
Query: 181 LKAGV 185
GV
Sbjct: 716 GSGGV 720
>UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1;
Chlamydomonas reinhardtii|Rep: CGMP-dependent protein
kinase - Chlamydomonas reinhardtii
Length = 1027
Score = 169 bits (411), Expect = 2e-40
Identities = 81/178 (45%), Positives = 118/178 (66%), Gaps = 3/178 (1%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
+D +Y + + GGEL+ + G F EP + FYAA ++LALE+LH +V+RDLKPE
Sbjct: 772 QDKASLYLLQEWVPGGELFHHLDVEGAFDEPTAMFYAANVLLALEFLHAKGIVYRDLKPE 831
Query: 68 NVLVSSSGYIKLADFGFCKII-KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIY 126
N+L+ + GYIK+ADFGF K I +T+T+CGTP+Y APE+I+ +G + D+WALGVLI+
Sbjct: 832 NLLLDTQGYIKMADFGFAKYIGGDKTYTICGTPDYQAPEVIMRRGTTKAADYWALGVLIF 891
Query: 127 EMIAAFPPFYS--SEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLK 182
EM+ PPF S +P + + L+G+F P ++ L+ LL+V+P KR GS K
Sbjct: 892 EMLVGDPPFKSLTGDPWDTFRRTLSGRFYVPNFISDQAADLIFKLLQVNPDKRLGSDK 949
>UniRef50_A0E7B2 Cluster: Chromosome undetermined scaffold_80, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_80,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 428
Score = 169 bits (411), Expect = 2e-40
Identities = 75/181 (41%), Positives = 118/181 (65%), Gaps = 4/181 (2%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L + + +Y ++ Y GGEL+ ++K+G F E +++FYAA+++L L+YLH +++R
Sbjct: 166 LRYAFQSQYKLYLVVDYMPGGELFYHLRKVGRFKEEVAKFYAAEILLGLQYLHENHIIYR 225
Query: 63 DLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSK-GYSFPVDW 118
DLKPEN+L+ +G+IKL DFG KI+ ++LCGTPEYLAPE++ +K GY DW
Sbjct: 226 DLKPENILLDENGHIKLTDFGLSKIMMEEDETAFSLCGTPEYLAPEILTTKTGYDKTCDW 285
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRY 178
W+ G L+YEM+ PP Y ++ +ILT P+ +++ ++L++ LL VDP KR
Sbjct: 286 WSFGALLYEMLVGAPPHYKENKKEMIRRILTQPIPYPQYLSENARSLLEQLLVVDPKKRL 345
Query: 179 G 179
G
Sbjct: 346 G 346
>UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme 1;
n=28; Eumetazoa|Rep: cGMP-dependent protein kinase,
isozyme 1 - Drosophila melanogaster (Fruit fly)
Length = 768
Score = 169 bits (411), Expect = 2e-40
Identities = 77/184 (41%), Positives = 119/184 (64%), Gaps = 4/184 (2%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D YVY +L GGE++T+++ G F + +QF ++ A EYLH +++RDLK
Sbjct: 525 TFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLK 584
Query: 66 PENVLVSSSGYIKLADFGFCKII--KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGV 123
PEN+++ GY+K+ DFGF K I S+TWT CGTPEY+APE+IL+KG+ VD+WALG+
Sbjct: 585 PENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEIILNKGHDRAVDYWALGI 644
Query: 124 LIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPTKRYGSL 181
LI+E++ PPF + +P++ Y IL G P+++++ L+K L P++R G
Sbjct: 645 LIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPSERLGYQ 704
Query: 182 KAGV 185
G+
Sbjct: 705 TGGI 708
>UniRef50_A5DTG0 Cluster: Serine/threonine-protein kinase YPK1; n=4;
Saccharomycetales|Rep: Serine/threonine-protein kinase
YPK1 - Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 788
Score = 168 bits (409), Expect = 3e-40
Identities = 82/180 (45%), Positives = 119/180 (66%), Gaps = 6/180 (3%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L F+ + +Y +L + GGEL+ +++ G F+ S+FY A+L+ ALE LH +V++R
Sbjct: 530 LKFSFQSPEKLYLVLSFINGGELFWHLQREGKFTMDRSRFYIAELLTALESLHELNVIYR 589
Query: 63 DLKPENVLVSSSGYIKLADFGFCKIIKS---RTWTLCGTPEYLAPELILSKGYSFPVDWW 119
DLKPEN+L+ G+I L DFG CK+ S +T T CGTPEYLAPEL++++GY+ VDWW
Sbjct: 590 DLKPENILLDYQGHIALCDFGLCKLNMSNDDKTNTFCGTPEYLAPELLINQGYTRSVDWW 649
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENM--TQVCKALVKNLLEVDPTKR 177
LG L+YEM+ PPFY S+ +Y+KIL + P+ + T L+K LL+ DP+KR
Sbjct: 650 TLGTLLYEMLTGLPPFYDSDVPTMYKKILQNPLRFPQFLEGTDAQDLLIK-LLQKDPSKR 708
>UniRef50_P11792 Cluster: Serine/threonine-protein kinase SCH9; n=2;
Saccharomyces cerevisiae|Rep: Serine/threonine-protein
kinase SCH9 - Saccharomyces cerevisiae (Baker's yeast)
Length = 824
Score = 168 bits (408), Expect = 4e-40
Identities = 85/187 (45%), Positives = 125/187 (66%), Gaps = 3/187 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ + +Y + Y +GGEL+ ++K G FSE ++FY A+LVLALE+LH +V
Sbjct: 476 VGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIV 535
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI-IKSRTWTLCGTPEYLAPELILSK-GYSFPVDW 118
+RDLKPEN+L+ ++G I L DFG K +K RT T CGT EYLAPEL+L + GY+ VD+
Sbjct: 536 YRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTKMVDF 595
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN-MTQVCKALVKNLLEVDPTKR 177
W+LGVLI+EM + PF++ K+Y+KI G+ K P + ++Q ++ VK LL +P R
Sbjct: 596 WSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHR 655
Query: 178 YGSLKAG 184
G++ G
Sbjct: 656 LGAIDDG 662
>UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14;
Apicomplexa|Rep: CGMP-dependent protein kinase -
Plasmodium falciparum
Length = 853
Score = 167 bits (407), Expect = 5e-40
Identities = 83/177 (46%), Positives = 112/177 (63%), Gaps = 3/177 (1%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T KD+ Y YF+ GGELY I+KLG S+ +QFY ++LA+EYLH ++V+RDLK
Sbjct: 607 TFKDSKYFYFLTELVTGGELYDAIRKLGLLSKSQAQFYLGSIILAIEYLHERNIVYRDLK 666
Query: 66 PENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
PEN+L+ GY+KL DFG K ++ R +TL GTP Y+APE+IL KGY VD WALG+ +
Sbjct: 667 PENILLDKQGYVKLIDFGCAKKVQGRAYTLVGTPHYMAPEVILGKGYGCTVDIWALGICL 726
Query: 126 YEMIAAFPPFYSSE--PIKLYEKILTGQFKTPENMTQVCKA-LVKNLLEVDPTKRYG 179
YE I PF + E ++++ ILTGQ P+ +T L+K LL P R G
Sbjct: 727 YEFICGPLPFGNDEEDQLEIFRDILTGQLTFPDYVTDTDSINLMKRLLCRLPQGRIG 783
>UniRef50_Q240P0 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 796
Score = 167 bits (407), Expect = 5e-40
Identities = 78/180 (43%), Positives = 117/180 (65%), Gaps = 6/180 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + + N +Y +L + GGEL+ +KK G FSE +++FYA+Q+V+ LE+LH ++
Sbjct: 141 VKLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGKFSEEVTRFYASQIVIGLEHLHQHKII 200
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSK-GYSFPVDWW 119
+RDLKPEN+L+ S G +KLADF + +LCGTPEYLAPE+I SK G+ VDWW
Sbjct: 201 YRDLKPENILLDSEGNLKLADFE-----NAPAHSLCGTPEYLAPEIITSKVGHDKTVDWW 255
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
+ G L+YEM+ PPFYS+ ++ I+ P+N++ K+L++ LL V+P R G
Sbjct: 256 SFGALVYEMLTGSPPFYSNNKKQMLHNIIYKPIPIPKNLSDTAKSLLQQLLVVNPKNRLG 315
>UniRef50_P54644 Cluster: RAC family serine/threonine-protein kinase
homolog; n=2; Dictyostelium discoideum|Rep: RAC family
serine/threonine-protein kinase homolog - Dictyostelium
discoideum (Slime mold)
Length = 444
Score = 167 bits (406), Expect = 7e-40
Identities = 77/181 (42%), Positives = 119/181 (65%), Gaps = 4/181 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L+++ + +YFIL Y GGEL+ ++K F+E ++Y A++VLALE+LH V+
Sbjct: 181 VNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGVI 240
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK----IIKSRTWTLCGTPEYLAPELILSKGYSFPV 116
+RDLKPEN+L+++ G+I + DFG CK +T T CGTPEYLAPE++ GY V
Sbjct: 241 YRDLKPENLLLTNEGHICMTDFGLCKEGLLTPTDKTGTFCGTPEYLAPEVLQGNGYGKQV 300
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTK 176
DWW+ G L+YEM+ PPFY+ + ++Y KI+ + P ++ ++L++ LLE DP K
Sbjct: 301 DWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLEQLLERDPEK 360
Query: 177 R 177
R
Sbjct: 361 R 361
>UniRef50_O96997 Cluster: Protein kinase C; n=2;
Tetractinomorpha|Rep: Protein kinase C - Geodia cydonium
(Sponge)
Length = 677
Score = 167 bits (405), Expect = 9e-40
Identities = 79/178 (44%), Positives = 118/178 (66%), Gaps = 4/178 (2%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
+++F++ Y +GG+L I +LG FSE ++FYAA++VL L YLH+ +++RDLK +NVL+
Sbjct: 420 HLFFVMEYVSGGDLMFHILELGRFSESQTRFYAAEIVLGLVYLHNLGIIYRDLKLDNVLL 479
Query: 72 SSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEM 128
S G++K+ADFG CK S+ T CGTP+Y+APE+I Y VDWWALGVLIYEM
Sbjct: 480 DSEGHVKIADFGLCKDGISGTSKARTFCGTPDYIAPEIIQYHPYDAAVDWWALGVLIYEM 539
Query: 129 IAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS-LKAGV 185
+ PPF + +L+ I+ Q P +++ C+ ++ LL + +KR GS +AGV
Sbjct: 540 LVGRPPFDGDDDDQLFMNIVQKQVHYPRGLSEPCRKIISGLLTKNASKRLGSHPEAGV 597
>UniRef50_A0CDF0 Cluster: Chromosome undetermined scaffold_17, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_17,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 416
Score = 167 bits (405), Expect = 9e-40
Identities = 74/182 (40%), Positives = 120/182 (65%), Gaps = 3/182 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + + +Y I+ + GGEL+ +++ F E ++FY+A+L+LA+EYLH ++
Sbjct: 136 VQLHYAFQTRTKLYLIMDFLIGGELFFHLRRAFRFQEERAKFYSAELILAIEYLHQRDII 195
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI-IKS--RTWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L+ G++K+ DFG KI +K +T T CGTPEYLAPE++L G++ VD
Sbjct: 196 YRDLKPENILLDMEGHLKITDFGLSKINLKDDEKTNTFCGTPEYLAPEILLGGGHNKCVD 255
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW+LG L+YEM+A PPFYS + ++++ L + + + ++++ LL+ DPTKR
Sbjct: 256 WWSLGALLYEMLAGAPPFYSKDKTQMFKNRLEKPIEMKDWFSSAARSILNGLLQNDPTKR 315
Query: 178 YG 179
G
Sbjct: 316 LG 317
>UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to
cGMP-dependent protein kinase 21D CG3324-PA; n=2;
Apocrita|Rep: PREDICTED: similar to cGMP-dependent
protein kinase 21D CG3324-PA - Apis mellifera
Length = 723
Score = 166 bits (404), Expect = 1e-39
Identities = 77/183 (42%), Positives = 121/183 (66%), Gaps = 3/183 (1%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T KD YVYF++ GG+++T +++ F + +QF +V AL++LH ++V+RDLK
Sbjct: 481 TYKDRKYVYFLMEVCLGGDVWTTLQRRRFFDDATAQFMVGCVVEALDHLHSMNIVYRDLK 540
Query: 66 PENVLVSSSGYIKLADFGFCKII-KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVL 124
PEN+++ GY+KL DFGF K I S+TWT GTPEY+APE+IL++G+ VD+WALG+L
Sbjct: 541 PENLMLDIRGYLKLVDFGFSKKIGPSKTWTFAGTPEYVAPEIILNRGHDRAVDYWALGIL 600
Query: 125 IYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPTKRYGSLK 182
I+E++ PPF S+ + +Y KI+ G P + + L+K LL ++P++R G +
Sbjct: 601 IHELLIGKPPFRGSDHMTIYNKIVKGIEVVGIPNTINKNANNLIKKLLRLNPSERLGYQR 660
Query: 183 AGV 185
G+
Sbjct: 661 NGI 663
>UniRef50_Q231C9 Cluster: Protein kinase C terminal domain
containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Protein kinase C terminal domain containing
protein - Tetrahymena thermophila SB210
Length = 358
Score = 166 bits (403), Expect = 2e-39
Identities = 76/183 (41%), Positives = 121/183 (66%), Gaps = 3/183 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L ++ +++ ++F L + GGEL++++ + F E +FYAAQ+VLA+E+LH +++
Sbjct: 92 IKLHYSFQNDTKLFFALDFCPGGELFSILSRKHKFDEEQCRFYAAQIVLAIEHLHKHNII 151
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK--IIKSRTWTLCGTPEYLAPELILSKGYSFPVDW 118
+RDLKPENV++ GYI+++DFG K I +++CGTPEYLAPE++ + G+ PVDW
Sbjct: 152 YRDLKPENVILDKEGYIRISDFGLSKDNIEDQTAFSVCGTPEYLAPEILNNSGHGKPVDW 211
Query: 119 WALGVLIYEMIAAFPPFY-SSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WALG LIYEM+ PPFY + +L++KI + P ++ CK L+ L +P +R
Sbjct: 212 WALGNLIYEMLTGLPPFYVENNREELFKKIKYTEITIPSYFSKACKDLLTRLFLKNPYQR 271
Query: 178 YGS 180
GS
Sbjct: 272 LGS 274
>UniRef50_Q6CD34 Cluster: Yarrowia lipolytica chromosome C of strain
CLIB122 of Yarrowia lipolytica; n=2; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome C of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 657
Score = 165 bits (402), Expect = 2e-39
Identities = 85/212 (40%), Positives = 131/212 (61%), Gaps = 8/212 (3%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L F+ + +Y L + GGEL+ +++ F ++FY A+L+ ALE LH ++V+R
Sbjct: 397 LKFSFQSPEKLYLGLAFVNGGELFYHLQRERFFDLNRARFYTAELLCALECLHDYNIVYR 456
Query: 63 DLKPENVLVSSSGYIKLADFGFCKIIKS---RTWTLCGTPEYLAPELILSKGYSFPVDWW 119
DLKPEN+L+ G+I L DFG CK+ + RT T CGTPEY++PE++L+KGY+ VDWW
Sbjct: 457 DLKPENILLDYMGHIVLCDFGLCKLNMTSDERTNTRCGTPEYMSPEILLNKGYNKSVDWW 516
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
LGVL+YEM+ PPFYS K+Y++IL + P+ M ++ LL+ +P++R G
Sbjct: 517 TLGVLLYEMLTGLPPFYSDNHNKMYQRILNDPLRFPQGMDPTAVDIITGLLQREPSERLG 576
Query: 180 SLKAGVFRALEYPAEMAKQDFHRERVLSERWN 211
AG A E A +D R+L+++++
Sbjct: 577 ---AG--GAQEIKAHPFFKDIDWNRLLAKKYS 603
>UniRef50_UPI00006CB3D2 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 327
Score = 165 bits (400), Expect = 4e-39
Identities = 78/175 (44%), Positives = 115/175 (65%), Gaps = 2/175 (1%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KD +FI+ Y GGELY +I+ G SE ++FYA+Q+++AL+YLH +V+RDLKPE
Sbjct: 86 KDKSCSFFIMEYVQGGELYDIIQNRGHLSEDAARFYASQVLIALDYLHQNDIVYRDLKPE 145
Query: 68 NVLVSSSGYIKLADFGFCKI-IKSRTW-TLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
N+L+ +GY+KL DFG ++ + S T +CGTPEY++PE++ GY VD WALGVLI
Sbjct: 146 NILLDENGYVKLTDFGLSEVEVVSPTLDKICGTPEYVSPEMLFESGYGKQVDHWALGVLI 205
Query: 126 YEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
+EMI PF + +L+EKI Q P ++ K+L++ L +P+KR G+
Sbjct: 206 FEMITGHTPFEAKSQEELFEKIKFSQVTYPACISPQLKSLLEGLFMKNPSKRLGA 260
>UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 617
Score = 165 bits (400), Expect = 4e-39
Identities = 78/186 (41%), Positives = 122/186 (65%), Gaps = 4/186 (2%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D+ +Y ++ GGE++T+++K G F L++FY A + ALEYLH ++V+RDLK
Sbjct: 375 TYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGAMEALEYLHRKNIVYRDLK 434
Query: 66 PENVLVSSSGYIKLADFGFCKIIKS--RTWTLCGTPEYLAPELILSKGYSFPVDWWALGV 123
PEN+L+ +G+ KL DFGF K +K+ RTWT CGT EY+APE++L+KG+ VD WALG+
Sbjct: 435 PENMLLDRNGWPKLVDFGFAKKLKNGGRTWTFCGTAEYVAPEIVLNKGHDLSVDIWALGI 494
Query: 124 LIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPTKRYGSL 181
+ E++ PPF S++P+ Y IL G ++ P +T+ ++ +L + +PT+R G
Sbjct: 495 FMCELLTGSPPFSSTDPMVTYNAILKGLEKWAWPRFVTKEAIDMMLSLCKYEPTERLGFG 554
Query: 182 KAGVFR 187
G R
Sbjct: 555 DIGEIR 560
>UniRef50_UPI000049A5C0 Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 439
Score = 164 bits (399), Expect = 5e-39
Identities = 78/170 (45%), Positives = 114/170 (67%), Gaps = 5/170 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+++++ Y GGELY+L+KK +E ++FYAAQLVLALE+LH+ +++RD+KPEN+L+
Sbjct: 194 LHYVIDYCPGGELYSLMKKEQTMNEKRTKFYAAQLVLALEHLHNQGIIYRDVKPENILIC 253
Query: 73 SSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
+ GYI+L DFG K+ S+T T CGTPEYLAPE+I + Y+ +DWW LGVLIYEM+
Sbjct: 254 ADGYIRLTDFGLSKMGISDNSKTATFCGTPEYLAPEVIQNVAYTNAIDWWGLGVLIYEML 313
Query: 130 AAFPPFYSSEPIKLYEKILTGQ--FKTPENMTQVCKALVKNLLEVDPTKR 177
PFY +LY IL Q F ++ C+ ++ LL+ +P +R
Sbjct: 314 YGTVPFYDENIQRLYHNILYNQVTFLEHTEISLECRDIISQLLKKNPIER 363
>UniRef50_A6RHI7 Cluster: Serine/threonine-protein kinase Sgk2; n=1;
Ajellomyces capsulatus NAm1|Rep:
Serine/threonine-protein kinase Sgk2 - Ajellomyces
capsulatus NAm1
Length = 459
Score = 164 bits (399), Expect = 5e-39
Identities = 81/191 (42%), Positives = 118/191 (61%), Gaps = 5/191 (2%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L F+ + +Y +L + GGEL+ +++ F ++FY A+L+ ALE LH +++R
Sbjct: 36 LKFSFQSPEKLYLVLAFVNGGELFHHLQREQRFDINRARFYTAELICALECLHGFKIIYR 95
Query: 63 DLKPENVLVSSSGYIKLADFGFCKII---KSRTWTLCGTPEYLAPELILSKGYSFPVDWW 119
DLKPEN+L+ +G+I L DFG CK+ + RT T CGTPEYLAPEL+L +GY+ VDWW
Sbjct: 96 DLKPENILLDYAGHIALCDFGLCKLDMKDEDRTNTFCGTPEYLAPELLLGEGYTKAVDWW 155
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPTKR 177
LGVL+YEM+ PPFY ++Y KIL F + + + + L+ LLE DP +R
Sbjct: 156 TLGVLLYEMLTGLPPFYDENTNEMYRKILQEPLTFPSQDIVPGAARDLLTRLLEGDPNRR 215
Query: 178 YGSLKAGVFRA 188
G+ A +A
Sbjct: 216 LGANGAAEIKA 226
>UniRef50_Q6PLK2 Cluster: Protein kinase B-like protein; n=4;
Plasmodium|Rep: Protein kinase B-like protein -
Plasmodium falciparum
Length = 446
Score = 164 bits (398), Expect = 6e-39
Identities = 79/171 (46%), Positives = 115/171 (67%), Gaps = 3/171 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YFIL Y GGEL+ + KL FSE ++FY+++++LALEYLH ++++RDLKPENVL+
Sbjct: 187 LYFILEYCPGGELFFHLSKLREFSEETAKFYSSEIILALEYLHDLNIIYRDLKPENVLLD 246
Query: 73 SSGYIKLADFGFCK--IIKSR-TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G+I+L DFG K I ++ T +LCGTPEYLAPE+I KG+ VDWW+LG+++YEM+
Sbjct: 247 ELGHIRLTDFGLSKEGITETNLTKSLCGTPEYLAPEIIEQKGHGKAVDWWSLGIMLYEML 306
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PF ++ L+E I + P+N++ L+ L E +P KR GS
Sbjct: 307 TGELPFNNTNRNVLFESIKYQKLNYPKNLSPKAVDLLTKLFEKNPKKRLGS 357
>UniRef50_A2F9U6 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 279
Score = 164 bits (398), Expect = 6e-39
Identities = 76/187 (40%), Positives = 113/187 (60%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D ++Y ++ + AGGE+++ ++ F +FYAA++ + E +H ++V+RDLK
Sbjct: 36 TFQDENFLYIMMEFIAGGEVFSHLRTNECFDPDTVRFYAAEVFMVFEEMHKNNIVYRDLK 95
Query: 66 PENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
PEN+L + G+IK DFGF KII+ RT+TLCGTPEYLAPE+I +G +F DWW+ GVLI
Sbjct: 96 PENLLFDAGGHIKFIDFGFAKIIEERTYTLCGTPEYLAPEIIRGEGTTFASDWWSYGVLI 155
Query: 126 YEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGV 185
+E+I PF LY I G + P + + + L +DPT+R GS AG
Sbjct: 156 HELICGHTPFAQLPEDDLYRSICEGVSEYPPEVDEATANFLDALFALDPTRRLGSGSAGT 215
Query: 186 FRALEYP 192
+P
Sbjct: 216 DEIKNHP 222
>UniRef50_A2DV83 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 740
Score = 163 bits (397), Expect = 8e-39
Identities = 79/188 (42%), Positives = 121/188 (64%), Gaps = 10/188 (5%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+Y ++ Y GG+LY+L+ +G E ++ Y AQ+V ALEYLH +VHRDLKP+N+L++
Sbjct: 395 LYLVMEYLPGGDLYSLLNNIGSLDETAARIYTAQIVKALEYLHSHGIVHRDLKPDNILIN 454
Query: 73 SSGYIKLADFG------FCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIY 126
SG +KL DFG + + I + T+ GTP+YLAPE+ILS +SF D+W+LG +IY
Sbjct: 455 ISGKLKLTDFGLSLYGAYDRAIPDDSKTIVGTPDYLAPEIILSSKHSFTADYWSLGCVIY 514
Query: 127 EMIAAFPPFYSSEPIKLYEKILTGQFKTP--ENMTQVCKALVKNLLEVDPTKRYGSLKAG 184
E + PPF+ ++ + +ILTG+F E+M+ L+K+LL+VDP KR G G
Sbjct: 515 EFLTGAPPFHMETEMETFAQILTGRFDIDPLEDMSDEVIDLIKHLLQVDPEKRLGF--NG 572
Query: 185 VFRALEYP 192
+ +++P
Sbjct: 573 IKEIMDHP 580
>UniRef50_Q2U061 Cluster: Ribosomal protein S6 kinase and related
proteins; n=20; Pezizomycotina|Rep: Ribosomal protein S6
kinase and related proteins - Aspergillus oryzae
Length = 681
Score = 163 bits (396), Expect = 1e-38
Identities = 82/198 (41%), Positives = 120/198 (60%), Gaps = 5/198 (2%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L F+ + +YF+L + GGEL+ +++ F ++FY A+L+ ALE LH V++R
Sbjct: 401 LKFSFQSPEKLYFVLAFVNGGELFHHLQREQRFDINRARFYTAELLCALECLHGFKVIYR 460
Query: 63 DLKPENVLVSSSGYIKLADFGFCKII---KSRTWTLCGTPEYLAPELILSKGYSFPVDWW 119
DLKPEN+L+ +G+I L DFG CK+ + RT T CGTPEYLAPEL+L GY+ VDWW
Sbjct: 461 DLKPENILLDYTGHIALCDFGLCKLDMKDEDRTNTFCGTPEYLAPELLLGNGYTKSVDWW 520
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPTKR 177
LGVL+YEM+ PPFY +Y KIL F + + + + L+ LL+ DP +R
Sbjct: 521 TLGVLLYEMLTGLPPFYDENTNDMYRKILQEPLTFPSTDIVPAAARDLLTRLLDRDPQRR 580
Query: 178 YGSLKAGVFRALEYPAEM 195
G+ A ++ + A +
Sbjct: 581 LGANGAAEIKSHHFFANI 598
>UniRef50_Q54IF2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 641
Score = 162 bits (394), Expect = 2e-38
Identities = 84/195 (43%), Positives = 121/195 (62%), Gaps = 5/195 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ F +D++ + +L Y GGEL+ I + FSE ++FY Q++LA+ +LH V+
Sbjct: 236 LKYSFQTQDSLCM--VLDYIGGGELFYHISERETFSEETARFYIGQIMLAIGFLHEHGVI 293
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK--IIKSR-TWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLK EN+L+ G I L D G CK I + T+T+CG+PEY+APE+I GYS VD
Sbjct: 294 YRDLKLENLLMDLDGNICLVDLGLCKEGIQEGHVTYTMCGSPEYVAPEIINGTGYSKSVD 353
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WWALG L YEMIA PPFYS +P ++ + IL+ K P +++ +LV LL DP+KR
Sbjct: 354 WWALGTLFYEMIAGLPPFYSEDPHEMTKLILSSPLKFPPQISKNAASLVSLLLNRDPSKR 413
Query: 178 YGSLKAGVFRALEYP 192
GS ++ V +P
Sbjct: 414 LGSGESDVEEIKAHP 428
>UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2;
Endopterygota|Rep: Cgmp-dependent protein kinase - Aedes
aegypti (Yellowfever mosquito)
Length = 966
Score = 162 bits (394), Expect = 2e-38
Identities = 78/191 (40%), Positives = 117/191 (61%), Gaps = 4/191 (2%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D Y+YF++ GG+++T+++K F E ++F A +V A EYLH ++++RDLK
Sbjct: 723 TYRDKKYLYFLMEACLGGDVWTILQKSKHFDERTARFMAGCVVEAFEYLHSRNMIYRDLK 782
Query: 66 PENVLVSSSGYIKLADFGFCKII--KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGV 123
PEN+++ GYIKL DFGF K I +TWT GTPEY++PE+IL+KG+ VD+WALGV
Sbjct: 783 PENLMLDEQGYIKLVDFGFAKRIGANQKTWTFAGTPEYVSPEIILNKGHDRAVDYWALGV 842
Query: 124 LIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPTKRYGSL 181
I+E++ PPF +K Y IL G + P + + + L+K L P +R G
Sbjct: 843 FIHELLVGKPPFRGKNHMKTYNAILRGIDIIELPSRIPKKAQVLIKRLCRQIPAERLGYG 902
Query: 182 KAGVFRALEYP 192
K G+ +P
Sbjct: 903 KNGIADIKNHP 913
>UniRef50_Q5K7C2 Cluster: Protein kinase Sch9, putative; n=4;
Agaricomycotina|Rep: Protein kinase Sch9, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 817
Score = 162 bits (394), Expect = 2e-38
Identities = 84/197 (42%), Positives = 125/197 (63%), Gaps = 6/197 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ + + +YF+ Y+ GGEL+ ++K G FSE ++FY A+LVLALE+LH ++V
Sbjct: 445 VGLKFSFQTDTELYFVTDYKCGGELFWHLQKEGRFSEDRARFYIAELVLALEHLHKYNIV 504
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELIL-SKGYSFPV 116
+RDLKPEN+L+ ++G++ L DFG K T T CGT EYLAPE++L KGY V
Sbjct: 505 YRDLKPENILLDATGHVALCDFGLSKPDLTDDKLTNTFCGTTEYLAPEVLLDEKGYGKHV 564
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMT-QVCKALVKNLLEVDPT 175
D+W+LGVL++EM + PFY+ + ++Y I G+ + P+N+ K VK LL +P
Sbjct: 565 DFWSLGVLLFEMCCGWSPFYAEQTQEMYRLICYGKIRFPKNVIGDDGKQFVKGLLNRNPQ 624
Query: 176 KRYGSLKAGVFRALEYP 192
R GS + G E+P
Sbjct: 625 NRLGSHR-GAVELKEHP 640
>UniRef50_Q24DD1 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 449
Score = 162 bits (393), Expect = 3e-38
Identities = 74/186 (39%), Positives = 122/186 (65%), Gaps = 6/186 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHC-SV 59
+ L + + +Y I+ Y GGEL+TL+K G F+E +++F A+++L ++YLH +
Sbjct: 165 VQLKYCIQTEKKIYLIMEYIQGGELFTLLKHCGQFTEKVAKFIIAEIILGIQYLHETLKI 224
Query: 60 VHRDLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSKGYSFPV 116
++RD+KPEN+L++ SG+IK++DFG K +++ T+T GTPEYLAPE++L+KG++ V
Sbjct: 225 IYRDIKPENILLTKSGHIKISDFGLSKEFQNKDEKTYTFAGTPEYLAPEIVLNKGHNKNV 284
Query: 117 DWWALGVLIYEMIAAFPPFYSSEP--IKLYEKILTGQFKTPENMTQVCKALVKNLLEVDP 174
D W +GV +YE++A +PPF K+ ++I+ + PEN + K L+K LL DP
Sbjct: 285 DLWGIGVFLYELVAGYPPFQDKNRNYDKISKQIIMNRPTYPENFSPNLKDLIKKLLNSDP 344
Query: 175 TKRYGS 180
R G+
Sbjct: 345 QMRLGA 350
>UniRef50_Q26334 Cluster: Serine/threonine protein kinase; n=2;
Entamoeba histolytica|Rep: Serine/threonine protein
kinase - Entamoeba histolytica
Length = 409
Score = 161 bits (392), Expect = 3e-38
Identities = 72/169 (42%), Positives = 109/169 (64%), Gaps = 2/169 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+Y ++ + GGEL+ +K FSE ++FYAA++ L ++H +++RDLKPEN+L+
Sbjct: 160 LYMVMDFVNGGELFYHLKNENCFSEERAKFYAAEIATVLIHIHSLGIIYRDLKPENILLD 219
Query: 73 SSGYIKLADFGFCKIIKS--RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIA 130
++G I + DFG K + + T T CGTP+YLAPE++ G+ VDWW+LG+LIYEMI
Sbjct: 220 NTGNIVITDFGLSKQLAAGEETQTFCGTPDYLAPEILKGVGHGPGVDWWSLGILIYEMIV 279
Query: 131 AFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
PPFY + +Y+KIL Q P N++ K+++ LLE DP +R G
Sbjct: 280 GIPPFYDDDVSLMYQKILKSQPHFPRNISYDAKSVIMGLLEKDPAERLG 328
>UniRef50_A0E058 Cluster: Chromosome undetermined scaffold_71, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_71,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 562
Score = 161 bits (392), Expect = 3e-38
Identities = 76/183 (41%), Positives = 113/183 (61%), Gaps = 4/183 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL++ + ++F++ + GGEL+ ++ F E +QFYAA ++LALEYLH VV
Sbjct: 295 ISLEYAFQTQEKLFFVMRFMRGGELFKHLRDKRRFPESTAQFYAASILLALEYLHKMQVV 354
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIK--SRTWTLCGTPEYLAPELILSKGYSFPVDW 118
+RDLKPEN+L+ GYIK+ D+G K +K T++ GTPEYLAPE+I G+ VDW
Sbjct: 355 YRDLKPENILMDEFGYIKMTDYGLAKFLKPGDFTYSFVGTPEYLAPEIIRQNGHGLGVDW 414
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQ--VCKALVKNLLEVDPTK 176
W+ G+LIYEM+ PPF+S +L++ I+ P +T K L+ LL +P +
Sbjct: 415 WSFGILIYEMVVGRPPFFSQNQSQLFKSIVESDVVFPSQLTLSIQIKDLITQLLTKNPFE 474
Query: 177 RYG 179
R G
Sbjct: 475 RLG 477
>UniRef50_Q9FXQ0 Cluster: Cyclic nucreotide dependent protein kinase
II; n=2; Chlamydomonas reinhardtii|Rep: Cyclic
nucreotide dependent protein kinase II - Chlamydomonas
reinhardtii
Length = 718
Score = 161 bits (390), Expect = 6e-38
Identities = 78/168 (46%), Positives = 111/168 (66%), Gaps = 7/168 (4%)
Query: 23 GELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVSSSGYIKLADF 82
G L +K L G SE L++FY +VLALEYLH+ ++V+RDLKPENV + +SGY+KL DF
Sbjct: 480 GCLAPKVKMLQGMSEDLARFYIGSIVLALEYLHNNNIVYRDLKPENVFIDASGYVKLGDF 539
Query: 83 GFCKIIK--SRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAAFPPF---YS 137
GF K+++ +RT+T CGTP Y+APE +L+ GY++ VDWW LGVL+Y ++ PF +
Sbjct: 540 GFAKVLENGNRTYTFCGTPGYVAPENVLAHGYNYSVDWWGLGVLMYVLLTGRQPFSTPKT 599
Query: 138 SEPIKLYEKIL--TGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKA 183
+P+ + +I+ Q K P ++ K L+ LLE P KR G L A
Sbjct: 600 DDPMVVMRRIVDENYQIKYPPYLSPAAKDLISRLLERKPAKRMGMLNA 647
>UniRef50_Q5CWD4 Cluster: Cyclic nucleotide (CGMP)-dependent protein
kinase with 3 cNMP binding domains and a Ser/Thr kinase
domain; n=3; Cryptosporidium|Rep: Cyclic nucleotide
(CGMP)-dependent protein kinase with 3 cNMP binding
domains and a Ser/Thr kinase domain - Cryptosporidium
parvum Iowa II
Length = 965
Score = 161 bits (390), Expect = 6e-38
Identities = 95/262 (36%), Positives = 142/262 (54%), Gaps = 11/262 (4%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T KD+ +Y + GGELY ++++G + +QFY ++LALEYLH S+V+RDLK
Sbjct: 688 TFKDSENIYLLTELIPGGELYDALQRIGLLTRYQAQFYIGSIILALEYLHERSIVYRDLK 747
Query: 66 PENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
PEN+L+ S GYIKL DFG K I R++TL GTP Y+APE+IL KGY+ D WA+G+ +
Sbjct: 748 PENILLDSQGYIKLIDFGCAKKIAGRSYTLAGTPHYMAPEVILGKGYNLSCDAWAIGICL 807
Query: 126 YEMIAAFPPFYSS--EPIKLYEKILTGQFKTPENMTQVCKA-LVKNLLEVDPTKRYGSLK 182
YE + PF + + +++++ ILT + P ++ V ++K LL P R G
Sbjct: 808 YEFLCGCLPFGNDAVDHLEIFKDILTSKLVFPRHLNDVDTVNIIKRLLCRVPEVRMGCSA 867
Query: 183 AGVFRALEYPAEMAKQDFHRERVLSERW--NLIRFVAQWTNGTEYFNGVE---ELLSHHL 237
G E + +DF+ +R+L + L+R + TE N VE E+ +
Sbjct: 868 TGY---KEIKDNVFFKDFNFDRLLGRSYVAPLVRKYRVFAKNTENENIVENITEVSQNEE 924
Query: 238 AIYEKVLEEASSDGISLEVEKN 259
A+ S IS KN
Sbjct: 925 ALSPNTHNIKSKQKISFNASKN 946
>UniRef50_A0BY36 Cluster: Chromosome undetermined scaffold_136,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_136,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 378
Score = 161 bits (390), Expect = 6e-38
Identities = 71/183 (38%), Positives = 118/183 (64%), Gaps = 3/183 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L + + +YF++ + GGEL+ +K++G E ++FY A+++LALEYLH +++
Sbjct: 109 VNLYYAFQTKQKLYFVIDFMIGGELFYHLKRIGKMEESWAKFYCAEIILALEYLHSQNII 168
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI-IKSR--TWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L+ G++K+ DFG CK+ IK T T+CGT +Y+APE+ L KG++ D
Sbjct: 169 YRDLKPENILLDQDGHVKITDFGLCKVDIKEGDFTTTICGTYDYMAPEIYLKKGHNQSAD 228
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
W++LG+L+Y M+ PPFYS ++ L Q + +++ L+K LL+ +P R
Sbjct: 229 WYSLGILLYVMLQGIPPFYSQNKRQMIRSRLERQIEIKTPISEEASDLIKQLLKNNPKDR 288
Query: 178 YGS 180
GS
Sbjct: 289 LGS 291
>UniRef50_UPI00006CB772 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 339
Score = 160 bits (389), Expect = 8e-38
Identities = 78/178 (43%), Positives = 113/178 (63%), Gaps = 4/178 (2%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T + +YF L Y GGEL+ L+ K F+E ++FY +Q++LA+E+LH +V++RDLK
Sbjct: 77 TFQSEKKLYFCLEYCPGGELFNLLYKKERFNEDQTRFYVSQMILAIEFLHEKNVIYRDLK 136
Query: 66 PENVLVSSSGYIKLADFGFCK-IIKS--RTWTLCGTPEYLAPELILSKGYSFPVDWWALG 122
PENVL+ GYI++ DFG K +K ++ GTPEYLAPE++ KGY VDWW LG
Sbjct: 137 PENVLIDKQGYIRVTDFGLSKQNVKGNYEAKSVVGTPEYLAPEILEGKGYGKTVDWWTLG 196
Query: 123 VLIYEMIAAFPPFYSSEPIK-LYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
+IYE++ PPFY E + L+++I + + +N CK LV +LL+ DP R G
Sbjct: 197 CIIYELLTGRPPFYKDEGKEDLFQQIQQNKVEIEKNWISDCKDLVLSLLQKDPKLRLG 254
>UniRef50_A0E8L1 Cluster: Chromosome undetermined scaffold_83, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_83,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 569
Score = 160 bits (389), Expect = 8e-38
Identities = 73/189 (38%), Positives = 120/189 (63%), Gaps = 3/189 (1%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
F+ + +V FIL + +GGEL+ +K L SE +QFY ++ +++ YLH +++RD+
Sbjct: 227 FSFESRNFVVFILEFCSGGELFYQLKTLKRMSEEQAQFYFVEICISMLYLHQMGIMYRDI 286
Query: 65 KPENVLVSSSGYIKLADFGFCKIIKSR--TWTLCGTPEYLAPELILSKGYSFPVDWWALG 122
KPEN+L+ G+I+++DFG K+ ++ CG+PEY+APE++L +G++ VD + LG
Sbjct: 287 KPENILLDLDGHIRISDFGLSKLTTPDEFAYSFCGSPEYMAPEMLLKRGHTIQVDHYCLG 346
Query: 123 VLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLK 182
L+YE++ PPFYS K+Y+ IL Q P+ ++Q K L+ LL DP KR G ++
Sbjct: 347 ALLYELVTGLPPFYSKNTQKIYDSILNEQVTFPQFLSQEIKDLMSGLLAKDPHKRLG-VR 405
Query: 183 AGVFRALEY 191
GV L++
Sbjct: 406 GGVREILQH 414
>UniRef50_A0CFD9 Cluster: Chromosome undetermined scaffold_175,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_175,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 383
Score = 160 bits (388), Expect = 1e-37
Identities = 76/174 (43%), Positives = 108/174 (62%), Gaps = 1/174 (0%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHC-SVVHRD 63
F ++ +++ ++ + GGEL+ + K F + + FYA+QLVLALE+LH V +RD
Sbjct: 132 FVFQEPLFINMVMEFVQGGELFYHLNKRKKFDQKTTAFYASQLVLALEFLHETVRVAYRD 191
Query: 64 LKPENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGV 123
LKPENVL+ GYIKLAD G K ++ CGT EYLAPE+I KG++ VD+W LG
Sbjct: 192 LKPENVLLCRDGYIKLADMGLAKDNSELNYSFCGTAEYLAPEMIEEKGHNASVDFWTLGC 251
Query: 124 LIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
+I+EM+ PPF LY KI TG+FK P + ++L+K LL+ P +R
Sbjct: 252 IIFEMLFGHPPFQDENKKNLYIKIQTGEFKFPPTASSSAQSLIKGLLQYHPEER 305
>UniRef50_UPI00006CDDB0 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 880
Score = 159 bits (386), Expect = 2e-37
Identities = 76/182 (41%), Positives = 119/182 (65%), Gaps = 5/182 (2%)
Query: 15 FILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVSSS 74
F+L Y GGEL+ + + F E + AQ++ +E+LH ++++RDLKPEN+L+ +
Sbjct: 237 FVLEYCPGGELFYHLNQERRFKEEQAGILFAQILEGIEFLHSKNIIYRDLKPENILLDMN 296
Query: 75 GYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAA 131
GY+KLADFG K++KS+ +T CG+ EY+APE+I KG++F VD+++LGVL+YE++A
Sbjct: 297 GYVKLADFGLSKVLKSKDQLNYTFCGSHEYMAPEMIQKKGHTFAVDYYSLGVLLYELVAG 356
Query: 132 FPPFYSSEPIKLYEKILTGQFK-TPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFRALE 190
PPF S L EK LT + K P+ + + +K L+ DPTKR G+ K+G+ +
Sbjct: 357 IPPFSSDNKTDLLEKALTKEVKFPPKQFSSQLQDFIKQLMIKDPTKRLGA-KSGISEIRK 415
Query: 191 YP 192
+P
Sbjct: 416 HP 417
>UniRef50_Q4SYX7 Cluster: Chromosome 21 SCAF11909, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 21
SCAF11909, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1114
Score = 159 bits (386), Expect = 2e-37
Identities = 76/182 (41%), Positives = 110/182 (60%), Gaps = 3/182 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L ++ + +YF+L Y GGEL+ +++ F EP ++FYAA++ AL YLH +V
Sbjct: 96 VGLHYSFQTTDKLYFVLDYVNGGELFYHLQRERIFLEPRARFYAAEIASALGYLHSLHIV 155
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L+ S G+I L DFG CK T T CGTPEYLAPE++ + Y VD
Sbjct: 156 YRDLKPENILLDSQGHIVLTDFGLCKEGLEANGTTTTFCGTPEYLAPEVLQKQAYDRTVD 215
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW LG ++YEM+ PPFYS ++Y IL N++ + L++ LL+ D +R
Sbjct: 216 WWCLGSVLYEMLYGLPPFYSRNTAEMYNNILHKSPVLKPNVSNAGRELLEGLLQKDRARR 275
Query: 178 YG 179
G
Sbjct: 276 LG 277
>UniRef50_Q24HP6 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 529
Score = 159 bits (386), Expect = 2e-37
Identities = 85/240 (35%), Positives = 145/240 (60%), Gaps = 9/240 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L++ + ++F + + GGEL+ +KK F E + FYA+Q++LALEYLH+ ++
Sbjct: 262 VNLEYAFQTKEKLFFAMKFVRGGELFFHLKKDKKFKESRALFYASQILLALEYLHNQDII 321
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIK--SRTWTLCGTPEYLAPELILSKGYSFPVDW 118
+RDLKPEN+L+ GY+K+ DFG K+++ T +L GTP+YL+PE+I KG++ D+
Sbjct: 322 YRDLKPENILLDQDGYVKITDFGLAKVLEKGKLTNSLVGTPDYLSPEIINQKGHNRTADY 381
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN--MTQVCKALVKNLLEVDPTK 176
WA G+LIYEM+ PPF+++ +++ I K P + +++ C ++ LL+ DP +
Sbjct: 382 WAFGILIYEMVIGIPPFFNNNQNVMFQLISEKDVKFPTSTPLSKECMDIILRLLKKDPNE 441
Query: 177 RYGSLKAGVFRALEYPAEMAKQDFHRERVLSERWNLIRFVAQWTNGTEYFNGVEELLSHH 236
R GS+ G E+P AK +F + +L+ + FV Q + T+ EE +S +
Sbjct: 442 RLGSVN-GTKDIKEHP-WFAKINF--DEILNRKVP-APFVPQLKSDTDVSCFDEEFISEN 496
>UniRef50_A2E5K8 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 450
Score = 159 bits (386), Expect = 2e-37
Identities = 74/179 (41%), Positives = 106/179 (59%), Gaps = 2/179 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F + YF L Y +GGEL+ ++K GG SE +FY +++VLAL YLH ++
Sbjct: 170 VQLKFAFQTPSKFYFGLEYASGGELFARVQKSGGLSEKEVRFYLSEIVLALSYLHSLGII 229
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIK--SRTWTLCGTPEYLAPELILSKGYSFPVDW 118
+RDLKPEN+L+ G++KL DFG K + S T CGT EY+APE+ + YS+ VDW
Sbjct: 230 YRDLKPENILLDEEGHVKLTDFGLSKDLNATSGAQTFCGTYEYIAPEIAQHQPYSYEVDW 289
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WA+G+L YEM+ PF+ ++ EKI+ P + +L+ LL DP KR
Sbjct: 290 WAIGILAYEMVMQVTPFFDKSQSRILEKIVNEDVSFPVEIPSELASLIAMLLRKDPKKR 348
>UniRef50_A0DDH0 Cluster: Chromosome undetermined scaffold_46, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_46,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 344
Score = 159 bits (386), Expect = 2e-37
Identities = 74/180 (41%), Positives = 121/180 (67%), Gaps = 3/180 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + +D+ +Y ++ Y GGEL+ I++ G F+ + +FY+AQ+++AL LH+ +++
Sbjct: 93 VELKYAFQDDRNLYMVVNYVKGGELFFHIREAGSFTLEICKFYSAQILMALLELHNQNII 152
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKII--KSRTWTLCGTPEYLAPELILS-KGYSFPVD 117
+RDLKPEN+L+ G++ L DFG K + T ++CGTPEYLAPE+I S GYSF VD
Sbjct: 153 YRDLKPENILLDEQGHVVLTDFGLSKHLCDDELTKSMCGTPEYLAPEIITSNNGYSFEVD 212
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
+++LG +IYEM+ PFYS+ ++++ LT + P+++ + +LV LLE+DP KR
Sbjct: 213 YYSLGCIIYEMLNGKTPFYSTNKRQMFQDRLTRKVTWPDSIDETAISLVNGLLEIDPLKR 272
>UniRef50_Q234E6 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 829
Score = 159 bits (385), Expect = 2e-37
Identities = 86/214 (40%), Positives = 129/214 (60%), Gaps = 15/214 (7%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KD+ +YF+L + G EL+ +I+++G S SQFY L+L LEYLH +++RD+KPE
Sbjct: 567 KDDRCIYFLLEFIQGMELFDVIREIGLLSTYDSQFYIGSLILTLEYLHSNYIIYRDIKPE 626
Query: 68 NVLVSSSGYIKLADFGFCKIIKS------RTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
N++V +GY+KL D G KI+KS RT+T+ GTP Y+APE+I KGY+F VD W++
Sbjct: 627 NIMVDHAGYLKLIDMGTAKIMKSKAGTVTRTFTIIGTPHYMAPEVISGKGYNFLVDLWSV 686
Query: 122 GVLIYEMIAAFPPF--YSSEPIKLYEKILTGQFKTPENMTQ-VCKALVKNLLEVDPTKRY 178
G+ +YE + + PF + +P ++YE+I+ + + P M V K L+ LL P R
Sbjct: 687 GICLYEFMCGYVPFAEEAEDPYEIYEEIIKKEIQFPAYMKDAVAKQLMLQLLNKIPEIRL 746
Query: 179 GSLKAGVFRALEYPAEMAKQDFHR--ERVLSERW 210
G G + AL+ A D+H+ ER L W
Sbjct: 747 G----GSYNALKSNAWFKNFDWHQLLERKLKAPW 776
>UniRef50_A7TPV4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 665
Score = 158 bits (384), Expect = 3e-37
Identities = 79/195 (40%), Positives = 127/195 (65%), Gaps = 4/195 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ + +Y + + +GGEL+ +++ G F E ++FY AQLV+ALE+LH ++
Sbjct: 326 VKLKFSFQTAEDLYLVTDFMSGGELFLHLQREGRFPEYRAKFYCAQLVMALEFLHDNDII 385
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI-IKSRTWTLCGTPEYLAPELIL-SKGYSFPVDW 118
+RDLKPEN+L+ + G I L DFG K+ ++ RT T CGT EYLAPEL+L + GY+ VD+
Sbjct: 386 YRDLKPENILLDAKGNIALCDFGLSKLNLEGRTNTFCGTTEYLAPELLLDATGYTKMVDF 445
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN-MTQVCKALVKNLLEVDPTKR 177
W+LGVL++EM + PF++ ++Y+KI + K P N +++ C+ +K L+ +P R
Sbjct: 446 WSLGVLMFEMCCGWSPFFAPTNQQMYQKIAYSKIKFPVNSLSKGCRLFIKGLMNRNPLHR 505
Query: 178 YGSLK-AGVFRALEY 191
G++ A RA E+
Sbjct: 506 LGAINDARELRAHEF 520
>UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, whole
genome shotgun sequence; n=8; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_42,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 825
Score = 158 bits (383), Expect = 4e-37
Identities = 79/182 (43%), Positives = 120/182 (65%), Gaps = 7/182 (3%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T KD++ +YF++ Y G EL+ +I+ +G ++ +QFY A ++LALEYLH S+V+RDLK
Sbjct: 563 TFKDDISIYFLVEYIRGMELFDVIRDMGLLTKYDTQFYVATMILALEYLHSKSIVYRDLK 622
Query: 66 PENVLVSSSGYIKLADFGFCK-IIKS---RTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
PEN++V+ +GY+ L D G K +IKS RT+T+ GTP Y+APE+IL KGYSF VD W++
Sbjct: 623 PENIMVNDAGYMYLIDLGTAKPLIKSRAYRTYTIIGTPHYMAPEIILGKGYSFNVDLWSM 682
Query: 122 GVLIYEMIAAFPPF--YSSEPIKLYEKILTGQFKTPENM-TQVCKALVKNLLEVDPTKRY 178
G+ +YE + P+ +P ++YE+I+ Q K P + + K ++ LL P R
Sbjct: 683 GICMYEFMCGGVPYAEEQDDPYEIYEEIMNTQLKFPTFIRDRQAKKFMEQLLSKQPETRL 742
Query: 179 GS 180
GS
Sbjct: 743 GS 744
>UniRef50_A2FLX7 Cluster: AGC family protein kinase; n=4;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 469
Score = 157 bits (382), Expect = 5e-37
Identities = 74/171 (43%), Positives = 101/171 (59%), Gaps = 3/171 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
++ +L Y GGEL++ +++ F E +++Y A+L A+ YLH + HRDLKPEN+L
Sbjct: 219 IFLVLDYVQGGELFSRLREERKFVEERARYYIAELAHAIGYLHSMGICHRDLKPENILFD 278
Query: 73 SSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
GYIKL DFG K ++ T T CGTPEYLAPE++ Y VDWWALG L YEM+
Sbjct: 279 KDGYIKLTDFGLVKEQMTKDATTTTFCGTPEYLAPEMVAGNAYDNNVDWWALGTLSYEML 338
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PPFY +Y IL PE+ T+ ++ LL+ +PT R GS
Sbjct: 339 YGVPPFYDVNTNAMYRSILRDDIVFPEDATEDAIDFIQKLLDKNPTTRLGS 389
>UniRef50_A2ELF7 Cluster: AGC family protein kinase; n=4;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 469
Score = 157 bits (382), Expect = 5e-37
Identities = 84/179 (46%), Positives = 107/179 (59%), Gaps = 2/179 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL FT + YF L Y GG+L ++G ++ YAAQ+ LA+ YLH +V
Sbjct: 176 VSLHFTFQTRSKFYFGLEYVPGGDLKFHKSQVGKIPIFDAKLYAAQIGLAITYLHGIGIV 235
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKS--RTWTLCGTPEYLAPELILSKGYSFPVDW 118
+RDLKPENVL+ GYIKL DFG K I T T CGTPEY++PELIL K Y + VD
Sbjct: 236 YRDLKPENVLLDGQGYIKLVDFGLSKDINQVKTTRTFCGTPEYISPELILKKNYGYAVDE 295
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WALGVL+YE+I PPF KLY+KI+ + K P + ++K LL DP KR
Sbjct: 296 WALGVLMYEIIFGDPPFVDENENKLYDKIVLEEPKYPADADPNLVDIIKKLLVKDPAKR 354
>UniRef50_A0C512 Cluster: Chromosome undetermined scaffold_15, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_15,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 342
Score = 157 bits (382), Expect = 5e-37
Identities = 75/180 (41%), Positives = 119/180 (66%), Gaps = 1/180 (0%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L FT ++ ++ + GG+L+ +K FSE ++FYA +L+LAL+YLH ++
Sbjct: 102 IKLYFTFENKNKLFLGTEFVNGGDLFVHLKNNVQFSEERTRFYAVELILALKYLHENRII 161
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSR-TWTLCGTPEYLAPELILSKGYSFPVDWW 119
+RDLKPEN+L+ G+IKL DFG K S+ T+T CGTPEY+APE++L +G++ VDW+
Sbjct: 162 YRDLKPENILLDQFGHIKLTDFGLSKYKFSQITYTACGTPEYVAPEILLERGHNECVDWY 221
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
+LG+LIY+M+ PFYS + ++ +K L+ F+ P+ + Q L+K L E + +KR G
Sbjct: 222 SLGILIYQMLCGSIPFYSKQLDEMIDKRLSQPFEFPKYLNQKAVDLIKGLTENEVSKRLG 281
>UniRef50_Q8INB9 Cluster: RAC serine/threonine-protein kinase; n=8;
Bilateria|Rep: RAC serine/threonine-protein kinase -
Drosophila melanogaster (Fruit fly)
Length = 611
Score = 157 bits (381), Expect = 7e-37
Identities = 82/195 (42%), Positives = 115/195 (58%), Gaps = 3/195 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL ++ + N + F++ Y GGEL+ + F+E ++FY A+++ AL YLH ++
Sbjct: 327 ISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGII 386
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK--IIKSRTW-TLCGTPEYLAPELILSKGYSFPVD 117
+RDLK EN+L+ G+IK+ADFG CK I RT T CGTPEYLAPE++ Y VD
Sbjct: 387 YRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVD 446
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW GV++YEMI PFY+ + L+ IL + K P N+T K L+ LL DP KR
Sbjct: 447 WWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKR 506
Query: 178 YGSLKAGVFRALEYP 192
G K V +P
Sbjct: 507 LGGGKDDVKEIQAHP 521
>UniRef50_UPI000049878B Cluster: protein kinase; n=3; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 434
Score = 157 bits (380), Expect = 1e-36
Identities = 76/181 (41%), Positives = 115/181 (63%), Gaps = 4/181 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKL-GGFSEPLSQFYAAQLVLALEYLHHCSV 59
+++ ++ + ++ FIL Y AGGEL++ ++K G E +FYAAQ+VLALE++H +
Sbjct: 179 VNMHYSFQTPTHLVFILDYCAGGELFSYLQKHPAGLPEVDVKFYAAQIVLALEHMHSTGI 238
Query: 60 VHRDLKPENVLVSSSGYIKLADFGFCKIIKSRTW-TLCGTPEYLAPELILSKGYSFPVDW 118
++RD+KPEN+L GY+++ DFG K K T T CGTPEYLAPE++ Y+ +DW
Sbjct: 239 IYRDIKPENILFEKDGYLRMTDFGLAKSTKKGTTNTFCGTPEYLAPEVVEGLDYNEYIDW 298
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN--MTQVCKALVKNLLEVDPTK 176
W LG+LIYEM+ PF + +LYE IL + K P +T+ C + +LL +P+K
Sbjct: 299 WGLGILIYEMLFTQSPFLAETMEELYENILQREPKYPSTKPITEECMNFINSLLIKEPSK 358
Query: 177 R 177
R
Sbjct: 359 R 359
>UniRef50_UPI00015A51B8 Cluster: Protein kinase C delta type (EC
2.7.11.13) (nPKC-delta).; n=1; Danio rerio|Rep: Protein
kinase C delta type (EC 2.7.11.13) (nPKC-delta). - Danio
rerio
Length = 649
Score = 157 bits (380), Expect = 1e-36
Identities = 76/195 (38%), Positives = 121/195 (62%), Gaps = 7/195 (3%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T + +++F++ Y GG+L I+ G F + FYAA+++ L+YLH +V+RDLK
Sbjct: 390 TFQSKEHLFFVMEYLNGGDLMFHIQDKGRFDLYRATFYAAEIICGLQYLHSKGIVYRDLK 449
Query: 66 PENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALG 122
+NV++ G+IK+ADFG CK I ++R T CGTP+Y+APE++L + YSF VDWW+ G
Sbjct: 450 LDNVMLDKDGHIKIADFGMCKENMIGENRATTFCGTPDYIAPEILLGQKYSFSVDWWSFG 509
Query: 123 VLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR---YG 179
VL+YEM+ PF + +L++ I P +T+ K L++ L E DPT+R G
Sbjct: 510 VLLYEMLIGQSPFQGDDEDELFDSIRMDVPHYPRWITKEAKDLLEKLFERDPTRRLGVVG 569
Query: 180 SLKA-GVFRALEYPA 193
+++ F+ + +PA
Sbjct: 570 NIRGHAFFKTINWPA 584
>UniRef50_Q4XNV1 Cluster: Rac-beta serine/threonine protein kinase,
putative; n=1; Plasmodium chabaudi|Rep: Rac-beta
serine/threonine protein kinase, putative - Plasmodium
chabaudi
Length = 698
Score = 157 bits (380), Expect = 1e-36
Identities = 72/171 (42%), Positives = 108/171 (63%), Gaps = 3/171 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YFIL Y GGEL+ + KL F+E +++FY +++++ L+YLH S+++RDLKPENVL+
Sbjct: 445 LYFILEYCPGGELFFHLSKLNKFTEEIARFYISEIIITLQYLHKLSIIYRDLKPENVLLD 504
Query: 73 SSGYIKLADFGF---CKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G+I+L DFG C + +LCGTPEYL+PE+I G+ DWW+LG+++YEM+
Sbjct: 505 KYGHIRLTDFGLSKKCISDNNSAKSLCGTPEYLSPEIIQQTGHGKSADWWSLGIMLYEMV 564
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PF L+E I + K P ++ L+K LL+ +P KR GS
Sbjct: 565 TGELPFSGESRDVLFENIKYKKIKIPNKLSPEVGDLLKKLLQKNPRKRLGS 615
>UniRef50_A2DS63 Cluster: AGC family protein kinase; n=3;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 453
Score = 157 bits (380), Expect = 1e-36
Identities = 70/177 (39%), Positives = 106/177 (59%), Gaps = 1/177 (0%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
+T + + ++ +L Y GGEL+ +K+ F+E + YAA++ L L YLH ++RDL
Sbjct: 192 YTFQTDAKIFMVLDYVPGGELFGRLKEESLFAESRVRLYAAEICLGLGYLHKLGFIYRDL 251
Query: 65 KPENVLVSSSGYIKLADFGFCKIIK-SRTWTLCGTPEYLAPELILSKGYSFPVDWWALGV 123
KPEN+LV G++K+ DFG K T T CGTPEY+APE++ Y+ VDWW+ G+
Sbjct: 252 KPENILVDQDGHLKITDFGLAKNTDMGTTSTFCGTPEYIAPEMLQRLPYTKAVDWWSYGI 311
Query: 124 LIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
+IYEM+ PPFY ++Y IL K P +++ ++L+ LL +P R GS
Sbjct: 312 IIYEMLTGLPPFYDENTNQMYRSILRDDVKYPSHVSHDARSLINQLLNRNPEARLGS 368
>UniRef50_A0DLX8 Cluster: Chromosome undetermined scaffold_56, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_56,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 371
Score = 157 bits (380), Expect = 1e-36
Identities = 76/170 (44%), Positives = 105/170 (61%), Gaps = 5/170 (2%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
++YF + Y GGE+Y L+ K FSE + FYAAQ++LALEYLH ++ RDLKPEN+++
Sbjct: 94 HLYFCMEYCPGGEMYYLLSKQKHFSEHTAMFYAAQIILALEYLHSKGIIFRDLKPENIVI 153
Query: 72 SSSGYIKLADFGFCK----IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
GY+KL DFG CK S ++CGTP Y+APE++LSK Y VDWWA G +YE
Sbjct: 154 CQDGYVKLTDFGLCKKGDFTNISGASSICGTPAYMAPEILLSKQYGKAVDWWAFGCFLYE 213
Query: 128 MIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
M+A PPF++S L I+ Q + + + L+ LLE +P R
Sbjct: 214 MVAGHPPFFASNKQDLEYSIVNSQ-PNMGHFSIKLQDLLYRLLEKNPKNR 262
>UniRef50_Q4RZQ9 Cluster: Chromosome 18 SCAF14786, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF14786, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 645
Score = 156 bits (379), Expect = 1e-36
Identities = 71/175 (40%), Positives = 113/175 (64%), Gaps = 3/175 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YF++ Y GG+L I+++G F EP + FYAA++ + L +LH +++RDLK +NV++
Sbjct: 389 LYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEIAVGLFFLHERGIIYRDLKLDNVMLD 448
Query: 73 SSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
S G+IK+ADFG CK + T T CGTP+Y+APE+I + Y VDWWA GVL+YEM+
Sbjct: 449 SEGHIKIADFGMCKENMVDGVCTRTFCGTPDYIAPEIIAYQPYGLSVDWWAYGVLLYEML 508
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAG 184
A PPF + +L++ I+ P+++++ ++ K L+ P+KR G + G
Sbjct: 509 AGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMAKLPSKRLGCGQEG 563
>UniRef50_O61225 Cluster: Serine/Threonine protein kinase; n=1;
Sycon raphanus|Rep: Serine/Threonine protein kinase -
Sycon raphanus
Length = 724
Score = 156 bits (379), Expect = 1e-36
Identities = 72/172 (41%), Positives = 111/172 (64%), Gaps = 3/172 (1%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
++YF++ Y GG+L I++ G FSE ++FY ++++ L++LH +++RDLK +NV++
Sbjct: 470 HLYFVMEYVNGGDLMFHIQQQGRFSEDRTRFYVSEIICGLQHLHSRGIIYRDLKLDNVML 529
Query: 72 SSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEM 128
SS G+IK+ADFG CK ++ T T CGTP+Y+APE+I + Y+ VDWWALGVL YEM
Sbjct: 530 SSRGHIKIADFGMCKENICGENTTSTFCGTPDYIAPEIIQGEQYNHSVDWWALGVLTYEM 589
Query: 129 IAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
+ PF + L++ I+ Q P +T+ A + LL +P KR GS
Sbjct: 590 LLGQSPFSGDDEESLFQSIMNDQVVYPVWLTREAAAFISKLLVREPDKRLGS 641
>UniRef50_Q96BR1 Cluster: Serine/threonine-protein kinase Sgk3;
n=68; Gnathostomata|Rep: Serine/threonine-protein kinase
Sgk3 - Homo sapiens (Human)
Length = 496
Score = 156 bits (379), Expect = 1e-36
Identities = 73/183 (39%), Positives = 110/183 (60%), Gaps = 3/183 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L ++ + +YF+L + GGEL+ +++ F E ++FYAA++ AL YLH +V
Sbjct: 224 VGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIV 283
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L+ S G++ L DFG CK I T T CGTPEYLAPE+I + Y VD
Sbjct: 284 YRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVD 343
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW LG ++YEM+ PPFY + ++Y+ IL ++ ++++ LLE D R
Sbjct: 344 WWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNR 403
Query: 178 YGS 180
G+
Sbjct: 404 LGA 406
>UniRef50_Q4DL90 Cluster: Rac serine-threonine kinase, putative;
n=2; Trypanosoma cruzi|Rep: Rac serine-threonine kinase,
putative - Trypanosoma cruzi
Length = 705
Score = 156 bits (378), Expect = 2e-36
Identities = 73/183 (39%), Positives = 112/183 (61%), Gaps = 3/183 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + + ++ +L + GGEL+ +++ F E ++FY A++ +A+EY+H SV+
Sbjct: 412 VKLYYAFQTKRHLILVLEFLCGGELFFHLQRCKRFDENRARFYTAEIGMAVEYIHSKSVL 471
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK--IIKS-RTWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+++ G++ L DFG K + + RT T CGTPEY+APEL+ G++ VD
Sbjct: 472 YRDLKPENLVLDREGHVVLTDFGLAKRDVAEDVRTHTFCGTPEYMAPELVKKSGHTTAVD 531
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW+LG +YEM+ PPFYS ++YE IL P + K+L+ LLE DP KR
Sbjct: 532 WWSLGAFLYEMVDGMPPFYSPNVAEMYEMILHKPLVCPARFSPELKSLLGRLLEKDPLKR 591
Query: 178 YGS 180
S
Sbjct: 592 MTS 594
>UniRef50_Q6C936 Cluster: Yarrowia lipolytica chromosome D of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome D of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 683
Score = 156 bits (378), Expect = 2e-36
Identities = 77/185 (41%), Positives = 125/185 (67%), Gaps = 5/185 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ + +YF+ Y +GGEL+ +++ G FSE ++FY A+LV+ALE+LH ++V
Sbjct: 374 VGLKFSFQTEADLYFVTDYMSGGELFWHLQREGRFSEQRAKFYIAELVIALEHLHDNNIV 433
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSK-GYSFPV 116
+RDLKPEN+L+ ++G+I L DFG K ++ T T CGT EYLAPE++L + GY+ V
Sbjct: 434 YRDLKPENILLDANGHIALCDFGLSKANVTQGDTTSTFCGTTEYLAPEVLLDESGYTKMV 493
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN-MTQVCKALVKNLLEVDPT 175
D+W+LGVLI+EM + PF++ + ++Y+ I G+ K P++ ++ ++ VK LL +P
Sbjct: 494 DFWSLGVLIFEMCCGWSPFHADDTQQMYKNIAFGKVKFPKDALSAEGRSFVKGLLNRNPE 553
Query: 176 KRYGS 180
R G+
Sbjct: 554 NRLGA 558
>UniRef50_Q9UBS0 Cluster: Ribosomal protein S6 kinase beta-2; n=68;
Eumetazoa|Rep: Ribosomal protein S6 kinase beta-2 - Homo
sapiens (Human)
Length = 482
Score = 156 bits (378), Expect = 2e-36
Identities = 74/170 (43%), Positives = 112/170 (65%), Gaps = 3/170 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+Y IL +GGEL+T +++ G F E + FY A++ LAL +LH +++RDLKPEN+++S
Sbjct: 144 LYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLS 203
Query: 73 SSGYIKLADFGFCK--IIKSR-TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
S G+IKL DFG CK I + T T CGT EY+APE+++ G++ VDWW+LG L+Y+M+
Sbjct: 204 SQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDML 263
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
PPF + K +KI+ G+ P +T + LVK L+ +P++R G
Sbjct: 264 TGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIG 313
>UniRef50_P05129 Cluster: Protein kinase C gamma type; n=98;
Eumetazoa|Rep: Protein kinase C gamma type - Homo
sapiens (Human)
Length = 697
Score = 155 bits (377), Expect = 2e-36
Identities = 70/171 (40%), Positives = 110/171 (64%), Gaps = 3/171 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YF++ Y GG+L I++LG F EP + FYAA++ + L +LH+ +++RDLK +NV++
Sbjct: 430 LYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLD 489
Query: 73 SSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
+ G+IK+ DFG CK + T T CGTP+Y+APE+I + Y VDWW+ GVL+YEM+
Sbjct: 490 AEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEML 549
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
A PPF + +L++ I+ P+++++ A+ K L P KR GS
Sbjct: 550 AGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGS 600
>UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2;
Eimeria|Rep: CGMP-dependent protein kinase - Eimeria
maxima
Length = 1007
Score = 155 bits (376), Expect = 3e-36
Identities = 78/177 (44%), Positives = 109/177 (61%), Gaps = 3/177 (1%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D ++YF+ GGELY I+KLG +QFY A +VLA+EYLH ++ +RDLK
Sbjct: 763 TFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHERNIAYRDLK 822
Query: 66 PENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
PEN+L+ S GY+KL DFG K ++ R +TL GTP Y+APE+IL KGY+ D WA GV +
Sbjct: 823 PENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTADTWAFGVCL 882
Query: 126 YEMIAAFPPF--YSSEPIKLYEKILTGQFKTPENMT-QVCKALVKNLLEVDPTKRYG 179
YE + PF + + ++++ IL G+ P +T Q L+K LL P R G
Sbjct: 883 YEFMCGPLPFGNDAEDQLEIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLPEVRIG 939
>UniRef50_A2FIJ5 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 461
Score = 155 bits (376), Expect = 3e-36
Identities = 71/171 (41%), Positives = 113/171 (66%), Gaps = 2/171 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YF++ YEAGG+L + + FS P + Y A+L LAL+ LH +V+RDLKPEN+L+
Sbjct: 186 LYFVMEYEAGGDLRHHMDQNTSFSLPQIRIYLAELALALKTLHGLGIVYRDLKPENILLD 245
Query: 73 SSGYIKLADFGFCKIIKSRT--WTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIA 130
+ G+IKLADFG K I S + ++CGT EY+APE++ S+ +F VDWW+ GV+ ++++
Sbjct: 246 AEGHIKLADFGLAKEINSESDATSICGTCEYIAPEMLRSQPQTFAVDWWSFGVIAFQLLC 305
Query: 131 AFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSL 181
PF S+ P +L++ I+ Q + P N+ ++ ++ LL +P KR GS+
Sbjct: 306 NRLPFASANPQRLFQLIMNNQPRIPNNLDSSAQSFLQQLLNKEPAKRLGSV 356
>UniRef50_A7SL27 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 710
Score = 155 bits (375), Expect = 4e-36
Identities = 75/170 (44%), Positives = 109/170 (64%), Gaps = 3/170 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
++F++ Y GG+L I+K F E S+FYAA++VLAL++LH V++RDLK +NVL+
Sbjct: 457 LFFVMEYVNGGDLMFQIQKSRKFDENRSRFYAAEVVLALQFLHQNGVIYRDLKLDNVLLD 516
Query: 73 SSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
+ G+IKLADFG CK T T CGTP+Y+APE++ + Y F VDWWALGVL+YEM+
Sbjct: 517 ADGHIKLADFGMCKENMAPGKTTTTFCGTPDYIAPEILQEQPYGFSVDWWALGVLMYEMM 576
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
A PPF + L+E IL P +++ +++K + + KR G
Sbjct: 577 AGQPPFEAENEEDLFESILHDDVLYPVWLSREAVSILKGFMTKNYLKRLG 626
>UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|Rep:
CG4839-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 1003
Score = 154 bits (374), Expect = 5e-36
Identities = 82/231 (35%), Positives = 138/231 (59%), Gaps = 8/231 (3%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +++ YVYF++ GG+++T++ K F E ++F A +V A +YLH ++RDLK
Sbjct: 759 TYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFIAGCVVEAFDYLHSHHFIYRDLK 818
Query: 66 PENVLVSSSGYIKLADFGFCKIIK--SRTWTLCGTPEYLAPELILSKGYSFPVDWWALGV 123
PEN+++ + GY KL DFGF K ++ +T T GTPEY+APE+IL +G+ VD+WALG+
Sbjct: 819 PENLMLGTDGYCKLVDFGFAKFVRQNEKTNTFAGTPEYVAPEIILDRGHDRAVDYWALGI 878
Query: 124 LIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPTKRYGSL 181
L+YE++ PF IK+Y++IL+G P + + + LV++L + P +R G
Sbjct: 879 LVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPSRIPKSAQHLVRHLCKQLPAERLGYQ 938
Query: 182 KAGVFRALEYPAEMAKQDFHRERVLSERWNLIRFVAQWTNGTEYF--NGVE 230
+ G+ ++ + D+ R ++ + R + WT+ +YF +GVE
Sbjct: 939 RKGI-ADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWTD-LQYFGPSGVE 987
>UniRef50_Q7R5X8 Cluster: GLP_81_97826_96747; n=2; Giardia
intestinalis|Rep: GLP_81_97826_96747 - Giardia lamblia
ATCC 50803
Length = 359
Score = 154 bits (374), Expect = 5e-36
Identities = 77/185 (41%), Positives = 110/185 (59%), Gaps = 10/185 (5%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T +D+ VY IL + GGEL+ +++ F + +F+A +++LAL YLH+ + +RDLK
Sbjct: 83 TYQDDKNVYIILDFIQGGELFYHLRRYNKFPLQVVKFFAVEILLALGYLHNLGIAYRDLK 142
Query: 66 PENVLVSSSGYIKLADFGFCK----------IIKSRTWTLCGTPEYLAPELILSKGYSFP 115
ENVLV ++G+IKLAD GF K + T+++ GTPEYLAPE+I S G+
Sbjct: 143 LENVLVDNTGHIKLADLGFAKRLVEKNADGDTVSQLTFSIVGTPEYLAPEIIRSTGHDMS 202
Query: 116 VDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPT 175
DWWA GVLIYEM+ PPF+ P +KIL G+ + K L+ LL D T
Sbjct: 203 ADWWAFGVLIYEMLTGSPPFFDDNPDMTCKKILGGKITFASGFDKAAKDLIIRLLNPDKT 262
Query: 176 KRYGS 180
+R G+
Sbjct: 263 RRLGA 267
>UniRef50_A0BD03 Cluster: Chromosome undetermined scaffold_10, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_10,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 363
Score = 154 bits (374), Expect = 5e-36
Identities = 77/182 (42%), Positives = 113/182 (62%), Gaps = 3/182 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + +++ +YFI+ Y GG+LY IK F + +FYAA+++ L++LH +V+
Sbjct: 109 VKLRYAFQNHARLYFIVDYMEGGDLYYHIKSQPTFPDKFIRFYAAEILFGLQHLHSLNVI 168
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKII---KSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L+S SG+IKL+DFG KI+ + T CGT +YLAPE++ ++GYSF D
Sbjct: 169 YRDLKPENILLSQSGHIKLSDFGLSKILDDFNDKADTCCGTIDYLAPEVLGNEGYSFACD 228
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
+++LG LIYEM PPFYS + + E Q + L+ LLEVDP KR
Sbjct: 229 FYSLGCLIYEMYFGMPPFYSKNKRLMIQNRSIRLVPFSEQCPQDARDLLTRLLEVDPKKR 288
Query: 178 YG 179
G
Sbjct: 289 LG 290
>UniRef50_Q22HC2 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 436
Score = 154 bits (373), Expect = 7e-36
Identities = 75/221 (33%), Positives = 132/221 (59%), Gaps = 10/221 (4%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+Y ++ + GGEL+ +++ F+E + +Y+A+++L +E LH ++++RDLKPEN+L+
Sbjct: 146 LYIVMDFMIGGELFYHLRRSPIFTEEKAAYYSAEIILGIEALHSNNIIYRDLKPENILID 205
Query: 73 SSGYIKLADFGFCKI-IKS--RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G+++LADFG K +K RT +LCGTPEYLAPE++L+ G++ VDWW+LG +IYEM+
Sbjct: 206 HKGHLRLADFGLSKKGVKDHERTNSLCGTPEYLAPEILLNNGHTKMVDWWSLGAIIYEML 265
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFRAL 189
PPFY+ ++++ + E + K+L+ LL ++P R G +
Sbjct: 266 TGAPPFYNKNQKQMFKDRFLKPIEMKEWFSPAAKSLLSGLLNINPELRLGFKGIQEIKEH 325
Query: 190 EYPAEMAKQDFHRERV-------LSERWNLIRFVAQWTNGT 223
E+ A + +++ + LS +++L F Q+T T
Sbjct: 326 EFYASINWDKLYKKEIPPPYKPKLSSKYDLSHFSKQFTTET 366
>UniRef50_Q21694 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 402
Score = 154 bits (373), Expect = 7e-36
Identities = 71/178 (39%), Positives = 114/178 (64%), Gaps = 3/178 (1%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L + + N +Y +L + GGELYTL+++ + E ++FY ++++LA+E+LH +V+R
Sbjct: 116 LHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIILAIEHLHGHDIVYR 175
Query: 63 DLKPENVLVSSSGYIKLADFGFCKI-IK--SRTWTLCGTPEYLAPELILSKGYSFPVDWW 119
DLKP+NV+++ +G++ L DFG CK +K +T T CGT EY+APE+I G+ VD W
Sbjct: 176 DLKPDNVMLNLAGHVVLTDFGLCKYKLKKGEKTLTFCGTHEYMAPEMIRKVGHDHAVDVW 235
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
ALG+L+Y+M PPF P + IL G+ + P ++ K L+K +++ DPT R
Sbjct: 236 ALGILMYDMFMGGPPFTGETPADKDKSILKGKVRLPPKLSASGKDLIKRIIKRDPTLR 293
>UniRef50_O61224 Cluster: Serine/Threonine protein kinase; n=1;
Sycon raphanus|Rep: Serine/Threonine protein kinase -
Sycon raphanus
Length = 756
Score = 154 bits (373), Expect = 7e-36
Identities = 72/178 (40%), Positives = 115/178 (64%), Gaps = 5/178 (2%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
F KD ++ F++ + GG+L I++ G F E ++ FY+A++VL L +LH V++RDL
Sbjct: 434 FQTKDRLF--FVMEFVNGGDLMYHIQQQGRFKENVAVFYSAEIVLGLFFLHRHGVIYRDL 491
Query: 65 KPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
K +NV++ G+IK+ADFG CK + +T T CGTP+Y+APE++ + Y+ VDWWAL
Sbjct: 492 KLDNVMLDHEGHIKIADFGMCKEGVLGAKQTRTFCGTPDYIAPEIVAYQPYNGSVDWWAL 551
Query: 122 GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
GVL+YEM++ PPF + +L+ IL + + P++MT+ ++ K+ L P R G
Sbjct: 552 GVLVYEMLSGQPPFDGEDEDELFSSILGDEVRFPKSMTREACSICKSFLAKHPAVRLG 609
>UniRef50_A0DTL3 Cluster: Chromosome undetermined scaffold_63, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_63,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 865
Score = 154 bits (373), Expect = 7e-36
Identities = 71/183 (38%), Positives = 116/183 (63%), Gaps = 3/183 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F + Y+Y +L Y GG+L I LG FSE ++FYAA+++LA+E+LH ++
Sbjct: 601 LGLHFAFQTPNYLYLVLDYCQGGDLSYHIANLGKFSEDTARFYAAEILLAIEFLHTKDII 660
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RD+KPEN+L+ S G++KLADFG K + + + CG+P YL+P+++ KG P D
Sbjct: 661 YRDMKPENILLDSQGHVKLADFGLSKEGVSDQDKAKSFCGSPAYLSPDILSQKGAGKPSD 720
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
+ +G ++YEM+ P+Y+ + ++Y+ I +G K P+ M+ K L+ +LE DP KR
Sbjct: 721 IYGIGCVMYEMMTGESPYYNDDIQQMYKNIQSGTLKWPKKMSVEAKNLLTKMLERDPNKR 780
Query: 178 YGS 180
G+
Sbjct: 781 IGT 783
>UniRef50_Q4PH11 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 753
Score = 154 bits (373), Expect = 7e-36
Identities = 78/185 (42%), Positives = 118/185 (63%), Gaps = 5/185 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ + +YF+ Y++GGEL+ +++ G F+E ++FY A+LVLALE+LH +V
Sbjct: 392 VGLKFSFQSATELYFVTDYKSGGELFWHLQREGRFTEERARFYIAELVLALEHLHKYDIV 451
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSK-GYSFPV 116
+RDLKPEN+L+ ++G++ L DFG K T T CGT EYLAPE++L + GYS V
Sbjct: 452 YRDLKPENILLDATGHVALCDFGLSKPDLGAGQLTNTFCGTTEYLAPEVLLDESGYSKLV 511
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN-MTQVCKALVKNLLEVDPT 175
D+W+LGVL++EM + PFY+ + ++Y I G+ K P + K VK LL +P
Sbjct: 512 DFWSLGVLLFEMCCGWSPFYAEDTQQMYRNICFGKIKFPRGAIGDDGKQFVKGLLNRNPR 571
Query: 176 KRYGS 180
R G+
Sbjct: 572 HRLGA 576
>UniRef50_A5DV85 Cluster: Serine/threonine-protein kinase SCH9; n=9;
Saccharomycetales|Rep: Serine/threonine-protein kinase
SCH9 - Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 844
Score = 154 bits (373), Expect = 7e-36
Identities = 96/266 (36%), Positives = 153/266 (57%), Gaps = 13/266 (4%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ + ++ + Y +GGEL+ ++K G FSE ++FY A+L+LALE+LH +V
Sbjct: 491 VGLKFSFQTPTDLFLVTDYMSGGELFWHLQKDGRFSEERAKFYIAELILALEHLHDNDIV 550
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSK-GYSFPV 116
+RDLKPEN+L+ ++G+I L DFG K + T T CGT EYLAPE++L + GY+ V
Sbjct: 551 YRDLKPENILLDANGHIALCDFGLSKANLNNDGTTNTFCGTTEYLAPEILLDESGYTKMV 610
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTP-ENMTQVCKALVKNLLEVDPT 175
D+W+LGVLI+EM + PFY+ ++Y+ I G+ + P E ++ ++ VK LL +P
Sbjct: 611 DFWSLGVLIFEMCCGWSPFYADNTQQMYKNIAFGKVRFPKEVLSPEGRSFVKGLLNRNPR 670
Query: 176 KRYGSLK-AGVFRALEYPAEMAKQDFHRERVLSERWNLIRFVAQWTNGTEYFNGVEELLS 234
R G+ A RA + A++ D R + + F + T+ N E S
Sbjct: 671 HRLGATNDARELRAHPFFADI-DWDLLRSKSIPP-----PFKPHLASETDTSNFDPEFTS 724
Query: 235 HHLAIYEKVLEEASSDGISLEVEKNF 260
++ +K +E AS+ +S V+ NF
Sbjct: 725 ESTSVLKKQMEMASTP-LSPGVQANF 749
>UniRef50_P31751 Cluster: RAC-beta serine/threonine-protein kinase;
n=115; root|Rep: RAC-beta serine/threonine-protein
kinase - Homo sapiens (Human)
Length = 481
Score = 154 bits (373), Expect = 7e-36
Identities = 74/180 (41%), Positives = 111/180 (61%), Gaps = 3/180 (1%)
Query: 15 FILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVSSS 74
F++ Y GGEL+ + + F+E ++FY A++V ALEYLH VV+RD+K EN+++
Sbjct: 227 FVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKD 286
Query: 75 GYIKLADFGFCK--IIKSRTW-TLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAA 131
G+IK+ DFG CK I T T CGTPEYLAPE++ Y VDWW LGV++YEM+
Sbjct: 287 GHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCG 346
Query: 132 FPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFRALEY 191
PFY+ + +L+E IL + + P ++ K+L+ LL+ DP +R G + +E+
Sbjct: 347 RLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEH 406
>UniRef50_UPI00006CFFA7 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 535
Score = 153 bits (372), Expect = 9e-36
Identities = 71/186 (38%), Positives = 117/186 (62%), Gaps = 5/186 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L + +DN +++F++ + GGELY +K+ G F+E ++FY AQL+LAL +LH +++
Sbjct: 277 VNLVYAFQDNQHIFFVMQFLKGGELYQYLKRDGRFTESRTKFYIAQLILALGHLHSKNII 336
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKII---KSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLK EN+++ S+GYI L DFG K I + T CGT EYL+PE++ G F D
Sbjct: 337 YRDLKLENIVMDSTGYICLTDFGLAKKIIHQQQIATTFCGTAEYLSPEILKGDGQDFTAD 396
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPENMTQVCKALVKNLLEVDPT 175
WWALG++ YE++ PF++ +++E+I +FK ++ K ++ L D T
Sbjct: 397 WWALGIICYELLYGNTPFHNKNAHQMFEQIKYAKLEFKNTVAISNEAKDFIEKCLTKDKT 456
Query: 176 KRYGSL 181
KR G++
Sbjct: 457 KRLGAI 462
>UniRef50_A2E8U1 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 417
Score = 153 bits (372), Expect = 9e-36
Identities = 74/181 (40%), Positives = 110/181 (60%), Gaps = 2/181 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + + + Y + Y GG L+ ++ G + Y A+L +AL +LH +V
Sbjct: 164 VQLHYAFQSDTKFYLCMEYVPGGTLFDHMRLSGTIPPDALKLYTAELAIALHHLHVNHIV 223
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKII-KSRTW-TLCGTPEYLAPELILSKGYSFPVDW 118
+RDLKPENVL+ G+IKL DFG K I +S T + CGTP+Y+APE++ K Y+ VDW
Sbjct: 224 YRDLKPENVLLDEDGHIKLTDFGSSKQIDESGTLHSFCGTPDYIAPEIVEGKPYTSKVDW 283
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRY 178
W+LG+LIYEM+ PPFYS P + Y+KI+ G P + + +L++ LL DP +R+
Sbjct: 284 WSLGILIYEMVFKAPPFYSVNPKRTYDKIVNGNIIFPGVVDENLVSLIRGLLNKDPMRRF 343
Query: 179 G 179
G
Sbjct: 344 G 344
>UniRef50_Q9HGS0 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=3; Sclerotiniaceae|Rep: CAMP-dependent
protein kinase catalytic subunit - Botrytis cinerea
(Noble rot fungus) (Botryotinia fuckeliana)
Length = 917
Score = 153 bits (372), Expect = 9e-36
Identities = 77/185 (41%), Positives = 121/185 (65%), Gaps = 5/185 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ + +Y + Y +GGEL+ ++K G F E ++FY A+L+LALE+LH +V
Sbjct: 578 VGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFDEQRAKFYIAELILALEHLHKHDIV 637
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK--IIKSRTW-TLCGTPEYLAPELILSK-GYSFPV 116
+RDLKPEN+L+ ++G+I L DFG K + K+ T T CGT EYLAPE++L + GY+ V
Sbjct: 638 YRDLKPENILLDANGHIALCDFGLSKANLTKNATTNTFCGTTEYLAPEVLLDEAGYTKMV 697
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTP-ENMTQVCKALVKNLLEVDPT 175
D+W+LGVL++EM + PFY+ + ++Y+ I G+ + P + +T + VK LL +P
Sbjct: 698 DFWSLGVLVFEMCCGWSPFYAEDTQQMYKNIAFGKVRFPRDTLTTEGRNFVKGLLNRNPK 757
Query: 176 KRYGS 180
R G+
Sbjct: 758 HRLGA 762
>UniRef50_P87253 Cluster: Protein kinase C-like; n=6;
Pezizomycotina|Rep: Protein kinase C-like - Neurospora
crassa
Length = 1142
Score = 153 bits (372), Expect = 9e-36
Identities = 83/239 (34%), Positives = 134/239 (56%), Gaps = 6/239 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
VYF++ Y +GG+L I++ G F +QFYAA++ LAL+Y H V++RDLK +N+L++
Sbjct: 893 VYFVMEYISGGDLMLHIQR-GMFGTKRAQFYAAEVCLALKYFHENGVIYRDLKLDNILLT 951
Query: 73 SSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G+IK+AD+G CK S T T CGTPE++APE++L K Y VDWWA GVLIY+M+
Sbjct: 952 LDGHIKIADYGLCKEDMWYGSTTSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQML 1011
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFRAL 189
PF + ++Y+ IL + P +M + ++++ LL +P +R GS +
Sbjct: 1012 LQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLLTREPDQRLGSGPTDAQEIM 1071
Query: 190 EYP--AEMAKQDFHRERVLSERWNLIRFVAQWTNGTEYFNGVEELLSHHLAIYEKVLEE 246
P + D + +RV I+ +N F V +L+ ++ + ++E
Sbjct: 1072 SQPFFRNINWDDIYHKRVQPPFLPQIKSATDTSNFDSEFTSVTPVLTPVQSVLSQAMQE 1130
>UniRef50_Q8SRK8 Cluster: Probable cAMP-dependent protein kinase
catalytic subunit; n=2; Encephalitozoon|Rep: Probable
cAMP-dependent protein kinase catalytic subunit -
Encephalitozoon cuniculi
Length = 322
Score = 153 bits (371), Expect = 1e-35
Identities = 71/180 (39%), Positives = 110/180 (61%), Gaps = 2/180 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
V I+ Y GGEL+ +KK G F E +++FYAA+++ AL ++H +++RDLKPEN+L++
Sbjct: 82 VGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALRFIHGRGILYRDLKPENILIT 141
Query: 73 SSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAAF 132
S+G+IKL DFGF + + GTPEY++PE + S+ D+W LGV+IYEM+
Sbjct: 142 STGHIKLIDFGFSVYESENIYMISGTPEYMSPEKLRSEDDGRASDYWGLGVMIYEMLCGD 201
Query: 133 PPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFRALEYP 192
PPFY S +Y KIL P ++ V + L+ LL+ + R G+ G+ + +P
Sbjct: 202 PPFYDSSADAIYHKILESNVVFPHYVSPVARCLITGLLDKNRATRLGT--KGICEIMGHP 259
>UniRef50_A0CSN3 Cluster: Chromosome undetermined scaffold_26, whole
genome shotgun sequence; n=6; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_26,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 774
Score = 153 bits (370), Expect = 2e-35
Identities = 68/188 (36%), Positives = 119/188 (63%), Gaps = 5/188 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ + + + Y+ F+L Y +GGEL+ L++K+ SE + FY A++ L ++ LH +++
Sbjct: 439 VKMQYAFESRKYLVFVLEYCSGGELFYLLRKVKKMSEEEAFFYFAEICLGMKNLHDNNII 498
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSKGYSFPVD 117
+RD+KPEN+L+ G++++ADFG K ++ CG+PEY+APE++L +G++F +D
Sbjct: 499 YRDIKPENILIDFEGHVRIADFGLSKPQMENQDIAYSFCGSPEYMAPEMLLKQGHTFQLD 558
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPE--NMTQVCKALVKNLLEVDPT 175
+ LG L+YE+I PPFYS ++Y+KIL + P M+Q+ K L+ +LL P
Sbjct: 559 LYCLGALLYELITGLPPFYSRNTDEMYQKILNQKLSFPSQLQMSQLLKDLLSSLLAKTPN 618
Query: 176 KRYGSLKA 183
KR +++
Sbjct: 619 KRIDDIES 626
>UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101,
whole genome shotgun sequence; n=17;
Oligohymenophorea|Rep: Chromosome undetermined
scaffold_101, whole genome shotgun sequence - Paramecium
tetraurelia
Length = 823
Score = 153 bits (370), Expect = 2e-35
Identities = 80/201 (39%), Positives = 122/201 (60%), Gaps = 10/201 (4%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KD+ ++YF++ Y G EL+ +I+ +G + SQFY A L+L +EYLH +V+RD+KPE
Sbjct: 566 KDDNFIYFLIEYIKGLELFDVIRDIGLLNTYDSQFYIASLLLCMEYLHTHHIVYRDIKPE 625
Query: 68 NVLVSSSGYIKLADFGFCKII--KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
NV+V GYI+L D G KI+ K RT+T+ GTP Y+APE++ KGYS+ VD W++G+ +
Sbjct: 626 NVMVDHHGYIRLIDMGTAKILKGKGRTFTIIGTPHYMAPEILNGKGYSYSVDLWSIGICL 685
Query: 126 YEMIAAFPPFY--SSEPIKLYEKILTGQFKTPENM-TQVCKALVKNLLEVDPTKR----Y 178
YE + PF + +P ++YE+I Q P ++ + K + LL P R Y
Sbjct: 686 YEFMCGGVPFAEDAEDPYEIYEEITKKQISYPNHLKDRKAKKFIDQLLNKTPEIRLGGSY 745
Query: 179 GSLKAGV-FRALEYPAEMAKQ 198
+LKA F L++ M K+
Sbjct: 746 AALKANTWFDGLDWDKLMDKE 766
>UniRef50_A2E8A4 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 687
Score = 152 bits (368), Expect = 3e-35
Identities = 71/179 (39%), Positives = 114/179 (63%), Gaps = 12/179 (6%)
Query: 14 YFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVSS 73
Y ++ Y GG+LY+L+ ++ E ++FYA Q+ ALEYLH C ++HRDLKP+N+LV +
Sbjct: 384 YIVMEYLPGGDLYSLLHEVYSIDEESAKFYAYQIAKALEYLHKCGIIHRDLKPDNILVDA 443
Query: 74 SGYIKLADFG--FCKIIKSR---------TWTLCGTPEYLAPELILSKGYSFPVDWWALG 122
+G +KL DFG + ++ R + +L GTP Y+APE+IL + +SFPVD+W+LG
Sbjct: 444 NGNLKLTDFGLSYLGVVDRRINSDENIVQSDSLVGTPNYVAPEIILGQKHSFPVDYWSLG 503
Query: 123 VLIYEMIAAFPPFYSSEPIKLYEKILTGQFK-TPENMTQVCKALVKNLLEVDPTKRYGS 180
++YE++ PPF + +L I+ G+F+ + + C+ + LL VDP+KR G+
Sbjct: 504 CVVYELLMGEPPFTADTEKELQNNIILGKFEHLDDEFSPECQDFISRLLTVDPSKRLGA 562
>UniRef50_A2E224 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 451
Score = 152 bits (368), Expect = 3e-35
Identities = 82/185 (44%), Positives = 106/185 (57%), Gaps = 10/185 (5%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQ--FYAAQLVLALEYLHHCS 58
+ + F+ +++ Y L Y +GGEL+ LI+ G P Q FY ++ LAL+YLH
Sbjct: 168 VGIKFSFQNDKKFYLGLEYVSGGELFKLIET--GHCVPFQQVRFYVMEVALALDYLHSIG 225
Query: 59 VVHRDLKPENVLVSSSGYIKLADFGFCKII------KSRTWTLCGTPEYLAPELILSKGY 112
V++RDLK ENVL++ SG+IKL DFG KI+ S T T CGTPEYLAPE+ILSK Y
Sbjct: 226 VIYRDLKLENVLMTKSGHIKLTDFGLSKIVADGKADNSTTSTFCGTPEYLAPEMILSKDY 285
Query: 113 SFPVDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEV 172
+DWWALGV YE PF K Y+ IL + K P N + + L
Sbjct: 286 GIEIDWWALGVFTYEFSYTITPFVGKTNKKTYDNILHEEPKFPPNADPNLVSFIMMCLRK 345
Query: 173 DPTKR 177
DPTKR
Sbjct: 346 DPTKR 350
>UniRef50_A0C5F6 Cluster: Chromosome undetermined scaffold_15, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_15,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 629
Score = 152 bits (368), Expect = 3e-35
Identities = 71/175 (40%), Positives = 113/175 (64%), Gaps = 2/175 (1%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
+++ ++ +L + GG+L L+ K SE +++FY +++LALE LH ++ RDLKP+
Sbjct: 390 QNSQKLFMVLDFCPGGDLGQLLTKQVKLSEEIARFYICEIILALESLHKNCIIFRDLKPD 449
Query: 68 NVLVSSSGYIKLADFGFCK--IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
NV++ S G+ +L DFG K I + T + CG+ YL+PE+++ KG+S VDW+ +GVL+
Sbjct: 450 NVVLDSKGHARLTDFGLSKEGIYDNITKSFCGSIAYLSPEVLMKKGHSRTVDWYLVGVLL 509
Query: 126 YEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
YEMI PP+Y +L+E I G K P++M+Q + L+K LL DP +R GS
Sbjct: 510 YEMIVGLPPYYHQNREQLFENIKKGVLKIPKHMSQDARELIKGLLIRDPAQRLGS 564
>UniRef50_A0BNJ0 Cluster: Chromosome undetermined scaffold_118,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_118,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 662
Score = 152 bits (368), Expect = 3e-35
Identities = 70/197 (35%), Positives = 126/197 (63%), Gaps = 6/197 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + + +V F+L + GGEL+ +K++ SE + FY +++ L L+ +H +++
Sbjct: 316 LHLSYAFESRQFVVFVLEFCQGGELFFQLKQIKRMSEEQACFYISEICLGLQEIHSLNIL 375
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RD+KPEN+L+ G++++ADFG K + + ++ CG+PEY+APE++L G+S VD
Sbjct: 376 YRDIKPENILMDIEGHVRIADFGLSKPEIGREEKAYSFCGSPEYMAPEMLLKLGHSQTVD 435
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMT--QVCKALVKNLLEVDPT 175
++ LG L+YE++ PP+YS+ ++Y+ IL + P ++T + K+L+ LLE DP
Sbjct: 436 FYCLGALLYELLTGLPPYYSTNTNQIYQDILYSKLSFPNDLTLSREVKSLLIALLEKDPI 495
Query: 176 KRYGSLKAGVFRALEYP 192
+R G+ K GV L++P
Sbjct: 496 QRLGA-KGGVQEILKHP 511
>UniRef50_Q39030 Cluster: Serine/threonine-protein kinase AtPK19;
n=19; Magnoliophyta|Rep: Serine/threonine-protein kinase
AtPK19 - Arabidopsis thaliana (Mouse-ear cress)
Length = 471
Score = 152 bits (368), Expect = 3e-35
Identities = 69/186 (37%), Positives = 117/186 (62%), Gaps = 3/186 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L ++ + +Y +L + GG L+ + G F E L++ Y A++V A+ +LH ++
Sbjct: 201 VQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIM 260
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIK--SRTWTLCGTPEYLAPELILSKGYSFPVDW 118
HRDLKPEN+L+ G++ L DFG K + +R+ ++CGT EY+APE++ KG+ DW
Sbjct: 261 HRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADW 320
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRY 178
W++G+L+YEM+ PPF S+ K+ +KI+ + K P+ ++ AL+K LL+ +P +R
Sbjct: 321 WSVGILLYEMLTGKPPFLGSKG-KIQQKIVKDKIKLPQFLSNEAHALLKGLLQKEPERRL 379
Query: 179 GSLKAG 184
GS +G
Sbjct: 380 GSGPSG 385
>UniRef50_UPI00004999BB Cluster: protein kinase; n=3; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 420
Score = 151 bits (367), Expect = 4e-35
Identities = 70/169 (41%), Positives = 108/169 (63%), Gaps = 4/169 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YF++ + GGEL+ ++ FS ++FYAA+++LALE+LH +++RDLKPENVL++
Sbjct: 171 LYFVMDFINGGELFYHLQNERRFSIARAKFYAAEILLALEHLHLHGIIYRDLKPENVLLN 230
Query: 73 SSGYIKLADFGFCKI-IKSR---TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEM 128
+ G++ + DFG K +K T T CGT YLAPE++L + Y VDWW+ G+L YEM
Sbjct: 231 ADGHVCITDFGLSKTGMKGEGDMTSTFCGTAAYLAPEILLGEKYDSAVDWWSFGILTYEM 290
Query: 129 IAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
+ PPFYS + ++Y+ I+ + P N K + LLE +PT+R
Sbjct: 291 MVGIPPFYSEDEREMYQNIVNEAVRYPPNTPSSIKTFIDALLEKNPTRR 339
>UniRef50_Q9NAH6 Cluster: Putative uncharacterized protein rsks-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein rsks-1 - Caenorhabditis elegans
Length = 580
Score = 151 bits (367), Expect = 4e-35
Identities = 68/171 (39%), Positives = 111/171 (64%), Gaps = 3/171 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+Y IL Y +GGEL+ +++ G F E +++FY +++V++LE+LH +++RDLKPEN+L+
Sbjct: 160 LYLILEYLSGGELFMHLEREGMFMENVAKFYLSEIVVSLEHLHQQGIIYRDLKPENILLD 219
Query: 73 SSGYIKLADFGFCKII---KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
+ G++KL DFG CK +T T CGT EY+APE+++ G+ VDWW+LG L+++M+
Sbjct: 220 AYGHVKLTDFGLCKEEIEGDQKTHTFCGTIEYMAPEILMRCGHGKAVDWWSLGALMFDML 279
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PPF + K +KIL G+ P ++ + L+K LL+ R G+
Sbjct: 280 TGGPPFTAENRRKTIDKILKGRLTLPAYLSNEARDLIKKLLKRHVDTRLGA 330
>UniRef50_Q2UNA7 Cluster: Ribosomal protein S6 kinase and related
proteins; n=5; Pezizomycotina|Rep: Ribosomal protein S6
kinase and related proteins - Aspergillus oryzae
Length = 897
Score = 151 bits (367), Expect = 4e-35
Identities = 78/197 (39%), Positives = 125/197 (63%), Gaps = 6/197 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ + +Y + Y +GGEL+ ++K G F E ++FY A+L+LAL++LH +V
Sbjct: 566 VGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFQEARAKFYIAELILALQHLHEHDIV 625
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELIL-SKGYSFPV 116
+RDLKPEN+L+ ++G+I L DFG K ++ T T CGT EYLAPE++L +GY+ V
Sbjct: 626 YRDLKPENILLDANGHIALCDFGLSKANLAQNDTTNTFCGTTEYLAPEVLLDEQGYTKMV 685
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN-MTQVCKALVKNLLEVDPT 175
D+W+LGVL++EM + PFY+ + ++Y+ I G+ + P + ++ + VK LL +P
Sbjct: 686 DFWSLGVLVFEMCCGWSPFYAEDTQQMYKNIAFGKVRFPRDALSTEGRNFVKGLLNRNPK 745
Query: 176 KRYGSLKAGVFRALEYP 192
R G+ KA E+P
Sbjct: 746 HRLGA-KADAKELKEHP 761
>UniRef50_UPI00006A0EC2 Cluster: UPI00006A0EC2 related cluster;
n=16; Xenopus tropicalis|Rep: UPI00006A0EC2 UniRef100
entry - Xenopus tropicalis
Length = 584
Score = 151 bits (366), Expect = 5e-35
Identities = 76/195 (38%), Positives = 112/195 (57%), Gaps = 4/195 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL T + ++++++ Y GG+++ I+ + EP FY A +VL LE LH +V
Sbjct: 66 VSLHGTFQTASHLFYVMEYLPGGDMFDFIRSVE-LEEPDVMFYTACIVLGLEALHQLGIV 124
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
HRDLK EN+L+ GY+K+ DFG K RT T+CGT Y+APE+ L GY D
Sbjct: 125 HRDLKLENLLLDRDGYLKIVDFGLSKDSFGYSDRTNTVCGTRTYMAPEIYLKLGYGMAAD 184
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WWALG+ IY M+ PF + +P++ IL + PE++++ L++ LLE DP R
Sbjct: 185 WWALGITIYIMLLYELPFNNKDPVEQMSSILYDDIELPEDLSEDACTLIQELLEKDPEFR 244
Query: 178 YGSLKAGVFRALEYP 192
GS AG E+P
Sbjct: 245 LGSGDAGAEMIKEHP 259
Score = 122 bits (295), Expect = 2e-26
Identities = 58/144 (40%), Positives = 86/144 (59%), Gaps = 4/144 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL T + ++++++ Y GG+++ I+ + EP FY A +VL LE LH +V
Sbjct: 419 VSLHGTFQTASHLFYVMEYLPGGDMFDFIRSVE-LEEPDVMFYTACVVLGLEALHQLGIV 477
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
HRDLK EN+L+ GY+K+ DFG K RT T+CGT Y+APE+ L GY D
Sbjct: 478 HRDLKLENLLLDRDGYLKIVDFGLSKDRFGYSDRTNTVCGTRTYMAPEIYLKLGYGMAAD 537
Query: 118 WWALGVLIYEMIAAFPPFYSSEPI 141
WWALG+ +Y M+ PF + +P+
Sbjct: 538 WWALGITVYIMLLYELPFNNKDPV 561
>UniRef50_A5K8X1 Cluster: Rac-beta serine/threonine protein kinase,
putative; n=4; Alveolata|Rep: Rac-beta serine/threonine
protein kinase, putative - Plasmodium vivax
Length = 755
Score = 151 bits (366), Expect = 5e-35
Identities = 74/171 (43%), Positives = 108/171 (63%), Gaps = 3/171 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YFIL Y GGEL+ + K+ +E + FY A+++LAL+YLH ++++RD+KPENVL+
Sbjct: 502 LYFILEYCPGGELFFHLSKMRELTEEAAIFYTAEIILALQYLHKLNIIYRDVKPENVLLD 561
Query: 73 SSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G+I+L DFG K + +LCGTPEYLAPE+I G+ VDWW+LG+++YEM+
Sbjct: 562 EMGHIRLTDFGLSKEGISDNNSARSLCGTPEYLAPEIIDQCGHGKAVDWWSLGIMLYEML 621
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PF SS L+E+I + P ++ L+K L E +P KR GS
Sbjct: 622 TGRLPFNSSSRAVLFERIKHETLRYPCFLSPDAVDLLKKLFEKNPKKRLGS 672
>UniRef50_Q59EH6 Cluster: 3-phosphoinositide dependent protein
kinase-1 variant; n=9; Euteleostomi|Rep:
3-phosphoinositide dependent protein kinase-1 variant -
Homo sapiens (Human)
Length = 492
Score = 151 bits (366), Expect = 5e-35
Identities = 72/184 (39%), Positives = 113/184 (61%), Gaps = 5/184 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L FT +D+ +YF L Y GEL I+K+G F E ++FY A++V ALEYLH ++
Sbjct: 181 VKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGII 240
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKII-----KSRTWTLCGTPEYLAPELILSKGYSFP 115
HRDLKPEN+L++ +I++ DFG K++ ++R + GT +Y++PEL+ K
Sbjct: 241 HRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKS 300
Query: 116 VDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPT 175
D WALG +IY+++A PPF + +++KI+ ++ PE + LV+ LL +D T
Sbjct: 301 SDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDAT 360
Query: 176 KRYG 179
KR G
Sbjct: 361 KRLG 364
>UniRef50_Q6C292 Cluster: Similar to sp|P24583 Saccharomyces
cerevisiae YBL105c PKC1 ser/thr protein kinase; n=1;
Yarrowia lipolytica|Rep: Similar to sp|P24583
Saccharomyces cerevisiae YBL105c PKC1 ser/thr protein
kinase - Yarrowia lipolytica (Candida lipolytica)
Length = 1252
Score = 151 bits (366), Expect = 5e-35
Identities = 73/198 (36%), Positives = 119/198 (60%), Gaps = 5/198 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
VYF++ Y +GG+L I+K G F +QFYAA+++L +++ H V++RDLK +N+L++
Sbjct: 1001 VYFVMDYVSGGDLMWHIQKEGVFKPGRAQFYAAEVLLGIKHFHDNGVIYRDLKLDNILLT 1060
Query: 73 SSGYIKLADFGFCKIIKS---RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G++K+AD+G CK T T CGTPE++APE++L + Y VDWWA GVLIY+M+
Sbjct: 1061 RDGHVKIADYGLCKEDMDYGRTTGTFCGTPEFMAPEILLEQRYGLAVDWWAFGVLIYQMV 1120
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS--LKAGVFR 187
PF + ++++ IL + + P + C +++ LL +P +R GS A
Sbjct: 1121 LGQSPFRGEDEDEIFDAILADEPRYPITLPGNCVSILTQLLTREPERRLGSGPRDAEEIM 1180
Query: 188 ALEYPAEMAKQDFHRERV 205
A Y A + D + +R+
Sbjct: 1181 AHPYFANVNFDDIYHKRI 1198
>UniRef50_O15530 Cluster: 3-phosphoinositide-dependent protein
kinase 1; n=31; Deuterostomia|Rep:
3-phosphoinositide-dependent protein kinase 1 - Homo
sapiens (Human)
Length = 556
Score = 151 bits (366), Expect = 5e-35
Identities = 72/184 (39%), Positives = 113/184 (61%), Gaps = 5/184 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L FT +D+ +YF L Y GEL I+K+G F E ++FY A++V ALEYLH ++
Sbjct: 143 VKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGII 202
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKII-----KSRTWTLCGTPEYLAPELILSKGYSFP 115
HRDLKPEN+L++ +I++ DFG K++ ++R + GT +Y++PEL+ K
Sbjct: 203 HRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKS 262
Query: 116 VDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPT 175
D WALG +IY+++A PPF + +++KI+ ++ PE + LV+ LL +D T
Sbjct: 263 SDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDAT 322
Query: 176 KRYG 179
KR G
Sbjct: 323 KRLG 326
>UniRef50_P90980 Cluster: Protein kinase C-like 2; n=49;
Eumetazoa|Rep: Protein kinase C-like 2 - Caenorhabditis
elegans
Length = 682
Score = 151 bits (366), Expect = 5e-35
Identities = 69/170 (40%), Positives = 110/170 (64%), Gaps = 3/170 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YF++ + GG+L I+++G F EP++ FYAA++ + L +LH +++RDLK +NV++
Sbjct: 422 LYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNVMLE 481
Query: 73 SSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G+IK+ DFG CK + T T CGTP+Y+APE+IL + Y VDWWA GVL++EM+
Sbjct: 482 RDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEML 541
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
A PPF + +L+ I P+++++ +L K LL +P+KR G
Sbjct: 542 AGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNPSKRLG 591
>UniRef50_UPI00015B57E6 Cluster: PREDICTED: similar to protein
kinase c; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to protein kinase c - Nasonia vitripennis
Length = 990
Score = 151 bits (365), Expect = 6e-35
Identities = 72/180 (40%), Positives = 112/180 (62%), Gaps = 5/180 (2%)
Query: 5 FTC-KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRD 63
F C + + +V F++ Y AGG+L I F EP + FY+A +VL L+YLH +++RD
Sbjct: 730 FACFQTDAHVCFVMEYAAGGDLMMHIHA-DVFGEPRAVFYSACVVLGLQYLHESRIIYRD 788
Query: 64 LKPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
LK +N+L+ + GY+K+ADFG CK RT T CGTPE+LAPE++ Y+ VDWW
Sbjct: 789 LKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWG 848
Query: 121 LGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
LGVLI+EM+ PF + ++++ I+ + + P ++ A+++ LL +P +R GS
Sbjct: 849 LGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAIMRRLLRKNPDRRLGS 908
>UniRef50_Q8MYF1 Cluster: Similar to Dictyostelium discoideum (Slime
mold). Protein kinase 2; n=2; Dictyostelium
discoideum|Rep: Similar to Dictyostelium discoideum
(Slime mold). Protein kinase 2 - Dictyostelium
discoideum (Slime mold)
Length = 456
Score = 151 bits (365), Expect = 6e-35
Identities = 70/183 (38%), Positives = 115/183 (62%), Gaps = 3/183 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L + ++ +Y ++ + GG+L+ ++K FSE +FY A+L+LALE+LH ++V
Sbjct: 189 VNLHYAFQNEKKLYLVMDFVNGGQLFYHLQKEAIFSEDQVRFYMAELILALEHLHDSNIV 248
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
HRDLKPEN+L+ S G+ L DFG K+ + T++ GT EY+APE+I VD
Sbjct: 249 HRDLKPENILLDSQGHCILTDFGLAKLEVKTNNETFSFAGTLEYMAPEMIQHATCGKAVD 308
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW++G+L+Y+M+ PPF + EKI++ + K P+ ++ ++L+ LL DPTKR
Sbjct: 309 WWSIGILMYDMMIGKPPFEHKNRALMQEKIISEKAKFPKFVSSSARSLINGLLTKDPTKR 368
Query: 178 YGS 180
G+
Sbjct: 369 LGA 371
>UniRef50_A2FDD2 Cluster: AGC family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 436
Score = 151 bits (365), Expect = 6e-35
Identities = 77/178 (43%), Positives = 107/178 (60%), Gaps = 1/178 (0%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+S +F + Y L Y AGGEL + L ++ Y A++VLAL++LH +V
Sbjct: 178 ISAEFAFQTPSKFYIGLEYAAGGELLHHLSNLPVVPIEDTKLYMAEVVLALQHLHTNHIV 237
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK-IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWW 119
+RDLKPENVL+ SG++KL DFG CK I + T CGT EYLAPE++L GY F VDWW
Sbjct: 238 YRDLKPENVLLDKSGHVKLTDFGLCKEITEEGAKTFCGTAEYLAPEVVLRLGYGFKVDWW 297
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
ALGVL+YE++ A PFY L++ I+ + P+ + L+K LL+ +P R
Sbjct: 298 ALGVLLYEILFAGTPFYDDNQAVLFDNIVNEEPNYPKFGHKAAIDLIKLLLQKEPENR 355
>UniRef50_A2DP41 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 725
Score = 151 bits (365), Expect = 6e-35
Identities = 70/180 (38%), Positives = 114/180 (63%), Gaps = 2/180 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL +T +Y ++ Y GG+L T++ LG E +++Y Q+V AL+ L +V
Sbjct: 362 VSLYYTLCGVNNLYIVMEYVPGGDLKTVLHHLGCMDEHNARYYIVQIVAALQDLRKHKIV 421
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI-IKSRTWTLCGTPEYLAPELILSKGYSFPVDWW 119
HRDLKP+N+L+ G++KLADFG + + +T GTP+Y+APE++L+KG+SFP D+W
Sbjct: 422 HRDLKPDNILIDRDGHLKLADFGLSFVGVVEKTLEFAGTPDYVAPEIVLNKGHSFPADYW 481
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
+LGV+IYE++ PPF+ P + + I G F+ P + ++ L++ LL +P +R G
Sbjct: 482 SLGVIIYELLTGVPPFHGKTPEETFMNICEGIFE-PIDGSKEAIDLIRQLLRPNPNERLG 540
>UniRef50_P50530 Cluster: Serine/threonine-protein kinase sck1; n=1;
Schizosaccharomyces pombe|Rep: Serine/threonine-protein
kinase sck1 - Schizosaccharomyces pombe (Fission yeast)
Length = 696
Score = 151 bits (365), Expect = 6e-35
Identities = 78/197 (39%), Positives = 122/197 (61%), Gaps = 6/197 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ + +Y I Y +GGEL+ ++ G F E ++FY A+LVLALE+LH ++
Sbjct: 366 VGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHLHKHDII 425
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELIL-SKGYSFPV 116
+RDLKPEN+L+ + G+I L DFG K + T T CGT EYLAPE++L KGY+ V
Sbjct: 426 YRDLKPENILLDADGHIALCDFGLSKANLSANATTNTFCGTTEYLAPEVLLEDKGYTKQV 485
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN-MTQVCKALVKNLLEVDPT 175
D+W+LGVL++EM + PFY+ + ++Y I G+ + P+ ++ ++ V+ LL +P
Sbjct: 486 DFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGVLSSEGRSFVRGLLNRNPN 545
Query: 176 KRYGSLKAGVFRALEYP 192
R G++ A E+P
Sbjct: 546 HRLGAV-ADTTELKEHP 561
>UniRef50_A0EFE8 Cluster: Chromosome undetermined scaffold_93, whole
genome shotgun sequence; n=6; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_93,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 647
Score = 150 bits (364), Expect = 8e-35
Identities = 68/193 (35%), Positives = 122/193 (63%), Gaps = 4/193 (2%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
++F + ++ F + Y GGE+++ +K+ +E ++FY ++ LA+ +LHH +++R
Sbjct: 312 IEFVFETKNWIIFGIEYCPGGEMFSYMKRAQKMTENQARFYITEVCLAIGFLHHQQMIYR 371
Query: 63 DLKPENVLVSSSGYIKLADFGFCKII---KSRTWTLCGTPEYLAPELILSKGYSFPVDWW 119
DLKPENVL+ +G+I+LADFG + + ++ CG+PEY+APE+ + G+++ VD++
Sbjct: 372 DLKPENVLIDITGHIQLADFGLARPNMQPEQNAYSFCGSPEYMAPEMFHNDGHNYLVDYY 431
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
LG L+YE + PPFY + +Y ++L Q P+ ++ K L++ L+ DP++R G
Sbjct: 432 CLGALLYEFVTGLPPFYCEDKNIIYTRLLNEQVTFPKQLSPEVKDLIRLLMIKDPSRRLG 491
Query: 180 SLKAGVFRALEYP 192
S K+GV L +P
Sbjct: 492 S-KSGVDDILAHP 503
>UniRef50_Q4T638 Cluster: Chromosome undetermined SCAF8942, whole
genome shotgun sequence; n=2; Clupeocephala|Rep:
Chromosome undetermined SCAF8942, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1547
Score = 150 bits (363), Expect = 1e-34
Identities = 75/190 (39%), Positives = 115/190 (60%), Gaps = 21/190 (11%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
++ ++ Y GG+ TL+K +G +++ Y A+ VLALEYLH+ +VHRDLKP+N+L+
Sbjct: 538 HLCMVMEYVEGGDCATLLKNIGALPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLI 597
Query: 72 SSSGYIKLADFGFCKI-IKSRTWTL-----------------CGTPEYLAPELILSKGYS 113
+S G+IKL DFG KI + S T L CGTPEY+APE+IL +GY
Sbjct: 598 TSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDTREFLDKQVCGTPEYIAPEVILRQGYG 657
Query: 114 FPVDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN---MTQVCKALVKNLL 170
PVDWWA+GV++YE + PF+ P +L+ ++++ + PE + Q + L+ LL
Sbjct: 658 KPVDWWAMGVILYEFLVGCAPFFGDTPEELFGQVISDEIIWPEEDEALPQDAQDLISKLL 717
Query: 171 EVDPTKRYGS 180
+P +R G+
Sbjct: 718 RQNPLERLGT 727
>UniRef50_Q23PX4 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila SB210
Length = 1706
Score = 150 bits (363), Expect = 1e-34
Identities = 65/190 (34%), Positives = 121/190 (63%), Gaps = 6/190 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L+++ + Y+ F + Y AGGEL+ ++++ SE +++FY ++ L ++YLH ++
Sbjct: 1025 LKLEYSFESKSYLGFCMEYCAGGELFYHLRRIKRMSEEMARFYFVEICLGIDYLHKRHII 1084
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RD+KPEN+L+ G++++ DFG K I ++ CG+PEY+APE+++ G+++ VD
Sbjct: 1085 YRDIKPENILLDLDGHVRIGDFGLSKPDMDINEHAYSFCGSPEYMAPEMLMKVGHTYTVD 1144
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN--MTQVCKALVKNLLEVDPT 175
++ LG L+YE++ PPFYS + +Y++IL+ P++ ++ K L+K LL P
Sbjct: 1145 FYCLGALLYELVTGLPPFYSHDTDAIYQRILSEDLDFPDHVELSIELKNLLKGLLAKHPQ 1204
Query: 176 KRYGSLKAGV 185
R G +K G+
Sbjct: 1205 NRLG-IKNGI 1213
>UniRef50_A2EEZ5 Cluster: AGC family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 417
Score = 150 bits (363), Expect = 1e-34
Identities = 70/180 (38%), Positives = 110/180 (61%), Gaps = 1/180 (0%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL T + +YF + Y GGEL+ +++ G F + Y A+L LA+EYLH +++
Sbjct: 167 VSLKTTFQTPTKLYFAMEYAPGGELFFHLERKGAFHIHDVRIYVAELALAIEYLHDNNII 226
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK-IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWW 119
+RD+KPEN+L+ S G++K+ DFG K + + T TLCG+P Y+APE+I Y VDWW
Sbjct: 227 YRDIKPENILLDSEGHVKITDFGLSKEMEEDTTSTLCGSPNYMAPEIITHTRYGPAVDWW 286
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
+LG+L+YEM+ PF + L I T + P N ++L+ LL+ +P++R+G
Sbjct: 287 SLGILMYEMLFGVQPFVNENKSVLLMMIATCRVSFPRNANPDAQSLILGLLQKNPSERFG 346
>UniRef50_A0DCJ0 Cluster: Chromosome undetermined scaffold_45, whole
genome shotgun sequence; n=7; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_45, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 775
Score = 150 bits (363), Expect = 1e-34
Identities = 75/188 (39%), Positives = 112/188 (59%), Gaps = 8/188 (4%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T KD + VYF+L Y G EL+ +I+ +G S SQFY A ++L EYLHH ++++RD+K
Sbjct: 515 TFKDTLDVYFLLEYVRGMELFDVIRDIGLLSTYDSQFYVASMILITEYLHHQNIIYRDIK 574
Query: 66 PENVLVSSSGYIKLADFGFCKIIKS-----RTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
PEN +V G++KL D G KI+K RT+T+ GTP Y+APE+I KGY+ VD W+
Sbjct: 575 PENFMVDDKGFLKLIDLGTAKIVKGKQGIIRTYTIIGTPHYMAPEIICGKGYNCLVDLWS 634
Query: 121 LGVLIYEMIAAFPPF--YSSEPIKLYEKILTGQFKTPENM-TQVCKALVKNLLEVDPTKR 177
+G+ +YE + PF + +P ++YE+I+ P + + K L+ LL P R
Sbjct: 635 IGICLYEFMCGMVPFGEEAEDPYEIYEEIIKKDITYPNYLKDKKAKKLMDQLLSRVPEVR 694
Query: 178 YGSLKAGV 185
G A +
Sbjct: 695 LGGSYASL 702
>UniRef50_Q0UME1 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1043
Score = 150 bits (363), Expect = 1e-34
Identities = 73/171 (42%), Positives = 110/171 (64%), Gaps = 4/171 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
VYF++ Y +GG+L I++ G F +QFYAA++ LAL+Y H V++RDLK +N+L++
Sbjct: 794 VYFVMEYISGGDLMLHIQR-GTFGTKRAQFYAAEVCLALKYFHENGVIYRDLKLDNILLT 852
Query: 73 SSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G+IK+AD+G CK S T T CGTPE++APE++L K Y VDWWA GVLIY+M+
Sbjct: 853 LDGHIKIADYGLCKEEMWYGSTTSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQML 912
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PF + ++Y+ IL + P +M + ++++ LL +P R GS
Sbjct: 913 LQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLLTREPEMRLGS 963
>UniRef50_A1CR23 Cluster: CAMP-dependent protein kinase, putative;
n=10; Pezizomycotina|Rep: CAMP-dependent protein kinase,
putative - Aspergillus clavatus
Length = 938
Score = 150 bits (363), Expect = 1e-34
Identities = 74/185 (40%), Positives = 121/185 (65%), Gaps = 5/185 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ + +Y + Y +GGEL+ ++K G F E ++FY A+L+LAL++LH +V
Sbjct: 604 VGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFQEARAKFYIAELILALQHLHDHDIV 663
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELIL-SKGYSFPV 116
+RDLKPEN+L+ ++G+I L DFG K ++ T T CGT EYLAPE++L +GY+ V
Sbjct: 664 YRDLKPENILLDANGHIALCDFGLSKANLTQNDTTNTFCGTTEYLAPEVLLDEQGYTKMV 723
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN-MTQVCKALVKNLLEVDPT 175
D+W+LGVL++EM + PFY+ + ++Y+ I G+ + P + ++ + VK LL +P+
Sbjct: 724 DFWSLGVLVFEMCCGWSPFYAEDTQQMYKNIAFGKVRFPRDALSTEGRNFVKGLLNRNPS 783
Query: 176 KRYGS 180
R G+
Sbjct: 784 HRLGA 788
>UniRef50_Q10364 Cluster: Serine/threonine-protein kinase sck2; n=1;
Schizosaccharomyces pombe|Rep: Serine/threonine-protein
kinase sck2 - Schizosaccharomyces pombe (Fission yeast)
Length = 646
Score = 150 bits (363), Expect = 1e-34
Identities = 77/185 (41%), Positives = 116/185 (62%), Gaps = 5/185 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L F+ + +Y + Y AGGEL+ ++K F E ++FY A+L+LAL+ LH +V
Sbjct: 330 VALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQALHKRGIV 389
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSK-GYSFPV 116
+RDLKPEN+L+ G+I L DFG K + + T T CGT +YLAPE+IL + GY V
Sbjct: 390 YRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTRTFCGTTDYLAPEVILDEAGYDMMV 449
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQV-CKALVKNLLEVDPT 175
D+W+LGVL+YEM + PFY+ +LY+ I+ G+ + P + V + L+K LL +P
Sbjct: 450 DFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGLLSVEARDLIKLLLNRNPK 509
Query: 176 KRYGS 180
R G+
Sbjct: 510 HRLGA 514
>UniRef50_P23443 Cluster: Ribosomal protein S6 kinase beta-1 (EC
2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1)
(70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase
alpha) (p70(S6K)-alpha); n=19; Bilateria|Rep: Ribosomal
protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal
protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal
protein S6 kinase 1) (p70 S6 kinase alpha)
(p70(S6K)-alpha) - Homo sapiens (Human)
Length = 525
Score = 150 bits (363), Expect = 1e-34
Identities = 69/171 (40%), Positives = 108/171 (63%), Gaps = 3/171 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+Y IL Y +GGEL+ +++ G F E + FY A++ +AL +LH +++RDLKPEN++++
Sbjct: 168 LYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLN 227
Query: 73 SSGYIKLADFGFCKII---KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G++KL DFG CK + T T CGT EY+APE+++ G++ VDWW+LG L+Y+M+
Sbjct: 228 HQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDML 287
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PPF K +KIL + P +TQ + L+K LL+ + R G+
Sbjct: 288 TGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGA 338
>UniRef50_Q39908 Cluster: CAMP-dependent protein kinase; n=1;
Gonyaulax polyedra|Rep: CAMP-dependent protein kinase -
Gonyaulax polyedra (Dinoflagellate)
Length = 332
Score = 149 bits (362), Expect = 1e-34
Identities = 69/180 (38%), Positives = 113/180 (62%), Gaps = 3/180 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L + + +Y ++ Y GGEL+ + + G FSE ++FY A+ A+ YLH +V+
Sbjct: 70 VTLHYAFQTPKKLYMVMEYCPGGELFFHLSRAGRFSEGRTRFYVAETSSAVAYLHQLNVI 129
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI-IKSR--TWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L+ G+ K+ DFG K I+ T+CGTPEYLAPE++ KG+ VD
Sbjct: 130 YRDLKPENLLIDGEGHAKITDFGLRKEGIQDNHSAMTMCGTPEYLAPEILDKKGHGKAVD 189
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
W+++G L YEM+ PPFY+ + KL+++I G+ P+ ++ + K ++ LL+ +P R
Sbjct: 190 WYSVGALTYEMLTGLPPFYTKDLQKLFDRIRRGELTYPDYVSVLAKEFLRALLQRNPDAR 249
>UniRef50_A1Z7T1 Cluster: CG2049-PC, isoform C; n=7; Fungi/Metazoa
group|Rep: CG2049-PC, isoform C - Drosophila melanogaster
(Fruit fly)
Length = 1407
Score = 149 bits (362), Expect = 1e-34
Identities = 72/180 (40%), Positives = 112/180 (62%), Gaps = 5/180 (2%)
Query: 5 FTC-KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRD 63
++C + +V F++ Y AGG+L I F EP + FYAA +VL L+YLH +++RD
Sbjct: 1147 YSCFQTEQHVCFVMEYAAGGDLMMHIHT-DVFLEPRAVFYAACVVLGLQYLHENKIIYRD 1205
Query: 64 LKPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
LK +N+L+ + GY+K+ADFG CK RT T CGTPE+LAPE++ Y+ VDWW
Sbjct: 1206 LKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWG 1265
Query: 121 LGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
LGVLI+EM+ PF + ++++ I+ + + P ++ A+++ LL +P +R GS
Sbjct: 1266 LGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGS 1325
>UniRef50_A0E8C9 Cluster: Chromosome undetermined scaffold_82, whole
genome shotgun sequence; n=14; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_82,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 910
Score = 149 bits (362), Expect = 1e-34
Identities = 68/182 (37%), Positives = 114/182 (62%), Gaps = 5/182 (2%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L + + Y+ F+L Y AGGEL+ ++KL +E ++FY ++ + + YLH ++V+R
Sbjct: 466 LHYAFETKYYIAFVLDYCAGGELFYHLRKLKRLNEQDAKFYFVEICIGMAYLHSKNIVYR 525
Query: 63 DLKPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWW 119
D+KPEN+L+ G++ L+DFG K ++ CG+PEY+APE+++ G+++ VD +
Sbjct: 526 DIKPENILLDLQGHLLLSDFGLSKPDMTADDFAYSFCGSPEYMAPEMLMKTGHNYLVDCY 585
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPE--NMTQVCKALVKNLLEVDPTKR 177
LG L+YE++ PPFYS ++Y ILT + P+ ++ V K L+ LL+ DPT+R
Sbjct: 586 CLGALLYELVTGLPPFYSHNTQEIYNSILTETVEFPQYVQISPVLKELILQLLQKDPTER 645
Query: 178 YG 179
G
Sbjct: 646 LG 647
>UniRef50_A0DTA2 Cluster: Chromosome undetermined scaffold_62, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_62,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 389
Score = 149 bits (362), Expect = 1e-34
Identities = 87/232 (37%), Positives = 135/232 (58%), Gaps = 8/232 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHH-CSV 59
+ L ++ + +Y ++ Y GGE + ++ K G E + F AA++VLALEYL++ V
Sbjct: 124 VQLKYSFQTPTKLYLVMEYINGGEFFKILTKTKGLPESIVAFVAAEVVLALEYLNNQLKV 183
Query: 60 VHRDLKPENVLVSSSGYIKLADFGFCKIIKS---RTWTLCGTPEYLAPELILSKGYSFPV 116
++RDLKPEN+L++++G++KL DFG + K + +TL GTPEYLAPE+I KG+SF V
Sbjct: 184 IYRDLKPENILLTTTGHVKLTDFGLATLRKDENVKNYTLAGTPEYLAPEIINKKGHSFEV 243
Query: 117 DWWALGVLIYEMIAAFPPFY--SSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDP 174
D W LG+LIYEMI +PPF K+ IL Q M+ LV+ LL+ +P
Sbjct: 244 DLWTLGILIYEMINGYPPFTVPDRNTQKILSLILQNQPAYTPIMSDEAVNLVQRLLKANP 303
Query: 175 TKRYGSLKAGVFRALEYPAEMAKQDFHRERVLSERWNLIRFVAQWTNGTEYF 226
+R G+ + G ++ ++Y AK + L+ + L F Q + +E F
Sbjct: 304 KERIGA-EMG-YQEIKYHPFFAKIKWSELYNLNVKSPLKTFAEQNASRSEGF 353
>UniRef50_A0CUG4 Cluster: Chromosome undetermined scaffold_28, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_28,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 532
Score = 149 bits (362), Expect = 1e-34
Identities = 73/175 (41%), Positives = 107/175 (61%), Gaps = 5/175 (2%)
Query: 9 DNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPEN 68
D+ +Y +LP+ GG+LYT +KK E +F AQL++AL Y+H V+RDLKPEN
Sbjct: 282 DDQLIY-VLPFYQGGDLYTHLKKETRLKEERVKFLVAQLIMALGYMHDKDYVYRDLKPEN 340
Query: 69 VLVSSSGYIKLADFGFCKIIKSR--TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIY 126
+L+ SSGYI L D G CK + + +++ G+ EY+APE+I + GY+ +DWW LG+L Y
Sbjct: 341 ILMDSSGYIALTDLGLCKQLPNNQLSYSFTGSVEYIAPEMITAVGYNRMIDWWMLGILAY 400
Query: 127 EMIAAFPPFYSSEPIKLYEKILTGQ--FKTPENMTQVCKALVKNLLEVDPTKRYG 179
E+I PFY +++E I + F T ++ CK + NLL DP +R G
Sbjct: 401 ELIFGITPFYCDNQSQVFESIQEREVRFSTNIAISLECKDFITNLLRKDPKERLG 455
>UniRef50_A0CC53 Cluster: Chromosome undetermined scaffold_166,
whole genome shotgun sequence; n=7; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_166,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 736
Score = 149 bits (362), Expect = 1e-34
Identities = 69/197 (35%), Positives = 123/197 (62%), Gaps = 6/197 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L++ + ++ F+L + +GGEL+ ++++ +E ++FY ++ LA+ YLH S+V
Sbjct: 318 IKLEYAFESKNFIIFVLEFCSGGELFWQLRQVKRMTEYQARFYFTEICLAMFYLHSLSIV 377
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RD+KPEN+L+ G+I++ADFG K + ++ CG+PEY+APE++L G++ VD
Sbjct: 378 YRDIKPENILIDIDGHIRIADFGLSKPNMTEEDYAYSFCGSPEYMAPEMLLKIGHNVQVD 437
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPE--NMTQVCKALVKNLLEVDPT 175
+ LG L+YE++ PP+YS + ++YE IL + PE N++ K L+K LL P+
Sbjct: 438 HYCLGALLYELVTGLPPYYSRDTEEIYESILNEELTFPEKLNLSNEIKDLLKGLLSKQPS 497
Query: 176 KRYGSLKAGVFRALEYP 192
+R + K G+ +P
Sbjct: 498 ERLCANK-GLLELFTHP 513
>UniRef50_A0BJU7 Cluster: Chromosome undetermined scaffold_110,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_110,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 379
Score = 149 bits (362), Expect = 1e-34
Identities = 70/180 (38%), Positives = 110/180 (61%), Gaps = 5/180 (2%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L + + +Y+++ Y AGGEL+ +++ F E QFYA ++++ALEYLH +++R
Sbjct: 122 LHYAFQTQQKLYYVIDYCAGGELFFHLRRAYKFKENQVQFYAVEIIIALEYLHDSKILYR 181
Query: 63 DLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSK--GYSFPVD 117
DLKPEN+L+ S G+IKL DFG KII +R ++++ GTPEYLAPE+ G+ D
Sbjct: 182 DLKPENILLCSDGHIKLIDFGLSKIISNRDKPSFSIVGTPEYLAPEIYSDDKLGHDESCD 241
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW+LG L+YEM+ PFYS + ++ Q + ++ C +L+ LL +P +R
Sbjct: 242 WWSLGALLYEMLTGAAPFYSQDRTMMFRNRTEKQIEMKPWFSEACSSLLTGLLNNNPKQR 301
>UniRef50_Q16513 Cluster: Serine/threonine-protein kinase N2; n=42;
Eumetazoa|Rep: Serine/threonine-protein kinase N2 - Homo
sapiens (Human)
Length = 984
Score = 149 bits (362), Expect = 1e-34
Identities = 73/180 (40%), Positives = 112/180 (62%), Gaps = 5/180 (2%)
Query: 5 FTC-KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRD 63
F C + +V F++ Y AGG+L I FSEP + FYAA +VL L+YLH +V+RD
Sbjct: 724 FACFQTKEHVCFVMEYAAGGDLMMHIHT-DVFSEPRAVFYAACVVLGLQYLHEHKIVYRD 782
Query: 64 LKPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
LK +N+L+ + G++K+ADFG CK RT T CGTPE+LAPE++ Y+ VDWW
Sbjct: 783 LKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWG 842
Query: 121 LGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
LGVLIYEM+ PF + ++++ I+ + + P ++ ++++ LL +P +R G+
Sbjct: 843 LGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGA 902
>UniRef50_UPI000065F79D Cluster: Protein kinase C delta type (EC
2.7.11.13) (nPKC-delta).; n=1; Takifugu rubripes|Rep:
Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).
- Takifugu rubripes
Length = 752
Score = 149 bits (361), Expect = 2e-34
Identities = 67/171 (39%), Positives = 108/171 (63%), Gaps = 3/171 (1%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
+++F++ Y GG+L I++ G F + FY+A++ L++LH +++RDLK +NV++
Sbjct: 504 HLFFVMEYLNGGDLMFHIQEKGRFDLHRATFYSAEISCGLQFLHSKGIIYRDLKLDNVML 563
Query: 72 SSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEM 128
G+IK+ADFG CK ++R T CGTP+Y+APE++L + YSF VDWW+ GVL+YEM
Sbjct: 564 DYEGHIKIADFGMCKENVFGENRATTFCGTPDYIAPEILLGQKYSFSVDWWSFGVLLYEM 623
Query: 129 IAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
+ PF+ + +L+E I P + + K L++ E DPT+R G
Sbjct: 624 LIGQSPFHGDDEDELFESIRMDTPHYPRWINKEAKDLIERFFERDPTRRLG 674
>UniRef50_A2ECT2 Cluster: AGC family protein kinase; n=3;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 437
Score = 149 bits (361), Expect = 2e-34
Identities = 76/181 (41%), Positives = 107/181 (59%), Gaps = 2/181 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L F + Y L Y GGELYT I + G S+ + AQ+ +AL YLH +V
Sbjct: 171 VALRFAFQTPAKFYLGLEYVPGGELYTRIHRDGYLSKMEYKMVIAQIAIALNYLHSIGIV 230
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK--IIKSRTWTLCGTPEYLAPELILSKGYSFPVDW 118
+RD+KPEN+L+ + GYIKLADFG K I ++T + CGTP+Y+APE I+ Y VDW
Sbjct: 231 YRDIKPENILIGADGYIKLADFGLAKDIITDNKTTSFCGTPKYIAPETIVGVPYDQSVDW 290
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRY 178
W+LG+L Y++I PFYS +Y IL + + P++ + + LLE DP KR
Sbjct: 291 WSLGILTYQLIYHKFPFYSQNVDAVYRMILNKKVEFPDSASPEEIDFISILLEKDPKKRA 350
Query: 179 G 179
G
Sbjct: 351 G 351
>UniRef50_Q02156 Cluster: Protein kinase C epsilon type; n=34;
Coelomata|Rep: Protein kinase C epsilon type - Homo
sapiens (Human)
Length = 737
Score = 149 bits (361), Expect = 2e-34
Identities = 75/178 (42%), Positives = 110/178 (61%), Gaps = 5/178 (2%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
F KD ++ F++ Y GG+L I++ F EP S+FYAA++ AL +LH V++RDL
Sbjct: 476 FQTKDRLF--FVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDL 533
Query: 65 KPENVLVSSSGYIKLADFGFCK--IIKS-RTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
K +N+L+ + G+ KLADFG CK I+ T T CGTP+Y+APE++ Y VDWWAL
Sbjct: 534 KLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWAL 593
Query: 122 GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
GVL+YEM+A PPF + L+E IL P +++ +++K + +P KR G
Sbjct: 594 GVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLG 651
>UniRef50_A3KP71 Cluster: Prkcq protein; n=4; Clupeocephala|Rep:
Prkcq protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 290
Score = 149 bits (360), Expect = 3e-34
Identities = 70/178 (39%), Positives = 112/178 (62%), Gaps = 5/178 (2%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
F K+N++ F++ Y GG+L I+ F P S FYAA+++ L++LH +V+RDL
Sbjct: 31 FQTKENLF--FVMEYLNGGDLMFHIQTCHRFDLPRSTFYAAEIICGLQFLHSKGIVYRDL 88
Query: 65 KPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
K +N+L+ + G+IK+ADFG CK I ++RT T CGTP+Y+APE++L + Y VDWW+
Sbjct: 89 KLDNILLDTDGHIKIADFGMCKENIIGEARTCTFCGTPDYIAPEILLGQKYGTSVDWWSF 148
Query: 122 GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
GVL+YEM+ PF+ + +L++ I T P +T+ + ++ L +P +R G
Sbjct: 149 GVLLYEMLIGQSPFHGHDEEELFQSIRTDDPCYPRWLTRDARDILVKLFVREPERRLG 206
>UniRef50_Q23NJ5 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1598
Score = 149 bits (360), Expect = 3e-34
Identities = 68/197 (34%), Positives = 118/197 (59%), Gaps = 6/197 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ LD+ + Y+ F + Y AGGE++ ++K+ +E ++FY ++ L ++YLH ++
Sbjct: 639 LQLDYAFESKNYIAFAMEYCAGGEMFYHLRKIKKMTEEQARFYFIEICLGIDYLHDRHII 698
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RD+KPEN+L+ G+I++ DFG K ++ CG+PEY+APE++L G+++PVD
Sbjct: 699 YRDIKPENILLDIDGHIRIGDFGLSKPDMDDNEFAYSFCGSPEYMAPEMLLKVGHAYPVD 758
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPE--NMTQVCKALVKNLLEVDPT 175
+ LG L+YE++ PPFYS ++Y+ IL+ P+ N++ K L++ LL P
Sbjct: 759 HYTLGALLYELVTGLPPFYSQITEEIYKSILSEDLTFPDHVNLSSELKNLLRGLLTKHPL 818
Query: 176 KRYGSLKAGVFRALEYP 192
+R G G L +P
Sbjct: 819 QRLGQ-NMGTKEILSHP 834
>UniRef50_O42632 Cluster: Protein kinase C-like; n=14; Fungi|Rep:
Protein kinase C-like - Cochliobolus heterostrophus
(Drechslera maydis)
Length = 1174
Score = 149 bits (360), Expect = 3e-34
Identities = 72/171 (42%), Positives = 110/171 (64%), Gaps = 4/171 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
VYF++ Y +GG+L I++ G F +QFYAA++ LAL+Y H V++RDLK +N++++
Sbjct: 925 VYFVMEYISGGDLMLHIQR-GQFGTKRAQFYAAEVCLALKYFHENGVIYRDLKLDNIMLT 983
Query: 73 SSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G+IK+AD+G CK S T T CGTPE++APE++L K Y VDWWA GVLIY+M+
Sbjct: 984 LDGHIKVADYGLCKEEMWYGSTTSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQML 1043
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PF + ++Y+ IL + P +M + ++++ LL +P R GS
Sbjct: 1044 LQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLLTREPEMRLGS 1094
>UniRef50_Q4T021 Cluster: Chromosome undetermined SCAF11390, whole
genome shotgun sequence; n=4; Clupeocephala|Rep:
Chromosome undetermined SCAF11390, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 895
Score = 148 bits (359), Expect = 3e-34
Identities = 72/170 (42%), Positives = 107/170 (62%), Gaps = 3/170 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
++F++ Y GG+L I++ F EP S+FYAA++ AL +LH VV+RDLK +N+L+
Sbjct: 646 LFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHRNGVVYRDLKLDNILLD 705
Query: 73 SSGYIKLADFGFCK--IIKS-RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
+ G+ KLADFG CK I+ T T CGTP+Y+APE++ Y VDWWALGVL+YEM+
Sbjct: 706 AEGHCKLADFGMCKEGIVGGVTTTTFCGTPDYIAPEILQELEYGASVDWWALGVLMYEMM 765
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
A PPF + L+E IL P +++ ++++ + +P KR G
Sbjct: 766 AGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILRAFMTKNPAKRLG 815
>UniRef50_A2BIH5 Cluster: Novel protein similar to vertebrate
protein kinase N2; n=4; Clupeocephala|Rep: Novel protein
similar to vertebrate protein kinase N2 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 970
Score = 148 bits (359), Expect = 3e-34
Identities = 72/179 (40%), Positives = 113/179 (63%), Gaps = 6/179 (3%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
F KD +V F++ Y AGG+L I FSEP + FYAA +VL L++LH +V+RDL
Sbjct: 713 FQTKD--HVCFVMEYAAGGDLMMHIHA-DVFSEPRATFYAACVVLGLQFLHEHKIVYRDL 769
Query: 65 KPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
K +N+L+ + G++K+ADFG CK + RT T CGTPE+LAPE++ Y+ VDWW L
Sbjct: 770 KLDNLLLDTEGFVKIADFGLCKEGMGYRDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGL 829
Query: 122 GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
GVLI+EM+ PF + ++++ I+ + + P ++ ++++ LL +P +R G+
Sbjct: 830 GVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRVLSTEAISIMRRLLRRNPERRLGA 888
>UniRef50_Q5C2X7 Cluster: SJCHGC09382 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC09382 protein - Schistosoma
japonicum (Blood fluke)
Length = 300
Score = 148 bits (359), Expect = 3e-34
Identities = 78/177 (44%), Positives = 108/177 (61%), Gaps = 6/177 (3%)
Query: 35 FSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVSSSGYIKLADFGFCKI---IKSR 91
FSE ++FY A++ LAL YLH+ +VV+RDLK EN+L+ G+IK+ADFG CK +
Sbjct: 1 FSEERAKFYGAEITLALGYLHNQNVVYRDLKLENLLLDKDGHIKIADFGLCKEDMHYGAS 60
Query: 92 TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQ 151
T T CGTPEYLAPE++L Y VDWW LGV++YEM+ PFYSS+ L+E IL
Sbjct: 61 TKTFCGTPEYLAPEVLLDNDYGRSVDWWGLGVVMYEMMCGRLPFYSSDHEVLFELILQES 120
Query: 152 FKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFRALEYPAEMAKQDFHRERVLSE 208
P ++Q + ++ LL DPT R G GV LE A + +R++++
Sbjct: 121 VSFPARLSQPAQDILSRLLIKDPTSRLG---GGVQDVLEVMAHLFFASVDWDRLITK 174
>UniRef50_Q245J7 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 397
Score = 148 bits (359), Expect = 3e-34
Identities = 68/180 (37%), Positives = 113/180 (62%), Gaps = 3/180 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + + +YF++ + GGE++ I+K F E +++FY ++LVLALEYLH +
Sbjct: 133 VQLKYAFQTTTKLYFVMDFMQGGEMFYHIRKAKYFKEDVARFYVSELVLALEYLHSKDTI 192
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI-IK--SRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L+ + G+IK+ DFG K +K +T T+CGTPEYLAPE++L + + VD
Sbjct: 193 YRDLKPENILLGADGHIKICDFGLSKQGVKDSDKTKTICGTPEYLAPEILLGQPHGKEVD 252
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
W++LG ++YE ++ PPFYS + ++Y++ + + L++ LL +P R
Sbjct: 253 WYSLGCVLYEFLSGAPPFYSRDKQQMYQQRINSDIQRKPQFQNDAWDLIQLLLAKNPKDR 312
>UniRef50_Q23DN8 Cluster: Cyclic nucleotide-binding domain
containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Cyclic nucleotide-binding domain containing
protein - Tetrahymena thermophila SB210
Length = 808
Score = 148 bits (359), Expect = 3e-34
Identities = 73/181 (40%), Positives = 112/181 (61%), Gaps = 9/181 (4%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KD+ VYF++ Y G EL+ +I+ +G + SQFY A ++L LEYLHH +V++RD+KPE
Sbjct: 549 KDSFDVYFLVEYVKGIELFDVIRDIGLLNTYDSQFYVASMILILEYLHHQNVIYRDMKPE 608
Query: 68 NVLVSSSGYIKLADFGFCKIIK------SRTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
N++V +GY+KL D G K +K +RT+T+ GTP Y+APE+I KGY+ VD W++
Sbjct: 609 NIMVDENGYLKLIDLGTAKFLKGRHGLGNRTFTIIGTPHYMAPEIICGKGYNCYVDLWSV 668
Query: 122 GVLIYEMIAAFPPF--YSSEPIKLYEKILTGQFKTPENM-TQVCKALVKNLLEVDPTKRY 178
G+ +YE + PF + +P ++YE I+ + P + + K L+ LL P R
Sbjct: 669 GICLYEFMCGMVPFGEEAEDPYEIYEDIIKKEINYPSYLKDKKAKKLMDQLLSRVPEVRL 728
Query: 179 G 179
G
Sbjct: 729 G 729
>UniRef50_A2DW86 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 423
Score = 148 bits (359), Expect = 3e-34
Identities = 73/181 (40%), Positives = 104/181 (57%), Gaps = 2/181 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL F + + VY L Y GGEL+ ++K G F + Y A++ LAL++LH V+
Sbjct: 168 VSLKFAFQTDTKVYLGLEYAPGGELFYHLQKFGSFPIDDVRIYIAEMALALDFLHKHGVI 227
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKII--KSRTWTLCGTPEYLAPELILSKGYSFPVDW 118
+RD+KPEN+L+ + G++KL DFG K + +S T T CGT EY+APE++ Y +DW
Sbjct: 228 YRDIKPENILLDAQGHVKLTDFGLAKDLTDESSTTTFCGTFEYMAPEVVARSSYGPAIDW 287
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRY 178
WALG+L YE++ PF S L+ I T K P + + NLL DP RY
Sbjct: 288 WALGILTYELLNGHSPFQSDNRALLFMSIRTQPPKFPARTDRNTIDFISNLLNKDPELRY 347
Query: 179 G 179
G
Sbjct: 348 G 348
>UniRef50_Q8TFJ3 Cluster: Protein kinase A catalytic subunit; n=1;
Mucor racemosus|Rep: Protein kinase A catalytic subunit
- Rhizomucor racemosus (Mucor circinelloides f.
lusitanicus)
Length = 605
Score = 148 bits (359), Expect = 3e-34
Identities = 70/186 (37%), Positives = 116/186 (62%), Gaps = 7/186 (3%)
Query: 2 SLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVH 61
+L ++ + +++ ++ Y GGEL+ +++ SE QF+AA++V A + +H ++V+
Sbjct: 310 NLKYSFQTTNHLFLVMDYFPGGELFDFLERERCLSEKRCQFFAAEIVCAFDNIHARNIVY 369
Query: 62 RDLKPENVLVSSSGYIKLADFGFCKIIKSRTWTLCGTP-----EYLAPELILSKGYSFPV 116
R+LKPE++L+ + G+I L DFG CK +K++ + G P EYLAPE+++ K Y
Sbjct: 370 RNLKPESILLDAHGHIALTDFGLCKQLKNKMDLIQGVPQVITQEYLAPEMVMQKPYGMAA 429
Query: 117 DWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN--MTQVCKALVKNLLEVDP 174
DWW+LGVL++E++ PPF+S E +L+ +IL K P +T+ K + LLE DP
Sbjct: 430 DWWSLGVLMFELLTGSPPFHSVEQGELFRQILEAPIKFPAGGCITEEAKDFICQLLERDP 489
Query: 175 TKRYGS 180
KR GS
Sbjct: 490 AKRLGS 495
>UniRef50_Q05655 Cluster: Protein kinase C delta type; n=61;
Eumetazoa|Rep: Protein kinase C delta type - Homo
sapiens (Human)
Length = 676
Score = 148 bits (359), Expect = 3e-34
Identities = 71/178 (39%), Positives = 111/178 (62%), Gaps = 5/178 (2%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
F KD+++ F++ + GG+L I+ G F + FYAA+++ L++LH +++RDL
Sbjct: 417 FQTKDHLF--FVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDL 474
Query: 65 KPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
K +NVL+ G+IK+ADFG CK +SR T CGTP+Y+APE++ Y+F VDWW+
Sbjct: 475 KLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSF 534
Query: 122 GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
GVL+YEM+ PF+ + +L+E I P +T+ K +++ L E +PTKR G
Sbjct: 535 GVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLG 592
>UniRef50_UPI00006CFF91 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 987
Score = 148 bits (358), Expect = 4e-34
Identities = 69/183 (37%), Positives = 116/183 (63%), Gaps = 3/183 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + + Y+Y +L Y +GG++ + + FSE + FY A+LVLA++++H VV
Sbjct: 732 LGLHYALQTPNYLYLVLDYCSGGDISSHLAYKRRFSEEEALFYIAELVLAIQHIHEKDVV 791
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L++S G+IKLADFG K +S+T + CGTP YL+PE++ +KG + D
Sbjct: 792 YRDLKPENILIASDGHIKLADFGLSKDNVTDQSKTKSFCGTPAYLSPEMLNNKGATKASD 851
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
+ +G ++YEM+ PP+Y+ + +Y+KI G P ++Q + ++ LL+ +P R
Sbjct: 852 LYGIGAVLYEMLTGDPPYYNDDIPTMYKKIKEGNLTYPSYVSQKARNIINGLLDRNPKTR 911
Query: 178 YGS 180
G+
Sbjct: 912 LGA 914
>UniRef50_A7TL28 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 376
Score = 148 bits (358), Expect = 4e-34
Identities = 71/172 (41%), Positives = 104/172 (60%), Gaps = 2/172 (1%)
Query: 9 DNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPEN 68
D+ VY ++ Y GGELY L+KK G ++ + Y Q+ AL Y+H ++HRDLKPEN
Sbjct: 187 DSKNVYLVMEYLIGGELYKLLKKNGPMNDITASNYVYQMTDALNYMHKRKIIHRDLKPEN 246
Query: 69 VLVSSSGYIKLADFGFC--KIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIY 126
+L+ + IKL DFG+ + TLCGT +YL+PELI S+ Y VD WALG+L Y
Sbjct: 247 ILIGFNNQIKLTDFGWSIYNPNNQKRKTLCGTIDYLSPELISSREYDENVDVWALGILTY 306
Query: 127 EMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRY 178
E++ PPF + Y++I K P N++ + L+ NLL+V P++R+
Sbjct: 307 ELVVGAPPFEEDTKEQTYKRIAKSDLKFPPNVSSEARDLITNLLKVVPSERF 358
>UniRef50_Q16512 Cluster: Serine/threonine-protein kinase N1; n=26;
Euteleostomi|Rep: Serine/threonine-protein kinase N1 -
Homo sapiens (Human)
Length = 942
Score = 148 bits (358), Expect = 4e-34
Identities = 70/172 (40%), Positives = 108/172 (62%), Gaps = 4/172 (2%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
+V F++ Y AGG+L I FSEP + FY+A +VL L++LH +V+RDLK +N+L+
Sbjct: 690 HVCFVMEYSAGGDLMLHIHS-DVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLL 748
Query: 72 SSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEM 128
+ GY+K+ADFG CK RT T CGTPE+LAPE++ Y+ VDWW LGVL+YEM
Sbjct: 749 DTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEM 808
Query: 129 IAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
+ PF + ++++ I+ + + P ++ +++ LL +P +R GS
Sbjct: 809 LVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGS 860
>UniRef50_Q4SG88 Cluster: Chromosome 17 SCAF14597, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 17
SCAF14597, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 754
Score = 147 bits (357), Expect = 6e-34
Identities = 75/182 (41%), Positives = 110/182 (60%), Gaps = 5/182 (2%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
F KD ++ F++ Y GG+L I++ F E S+FYAA++ AL +LH V++RDL
Sbjct: 496 FQTKDRLF--FVMEYVNGGDLMFQIQRSRKFDEARSRFYAAEVTSALMFLHRHGVIYRDL 553
Query: 65 KPENVLVSSSGYIKLADFGFCK--IIKS-RTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
K +N+L+ + G+ KLADFG CK I+ T T CGTP+Y+APE++ Y VDWWAL
Sbjct: 554 KLDNILLDADGHCKLADFGMCKEGILNGITTTTFCGTPDYIAPEILQELDYGPSVDWWAL 613
Query: 122 GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSL 181
GVL+YEM+A PPF + L+E IL P +++ +++K + P KR G +
Sbjct: 614 GVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKSPNKRLGCV 673
Query: 182 KA 183
A
Sbjct: 674 VA 675
>UniRef50_Q7QUE9 Cluster: GLP_59_15138_16382; n=2; Giardia
intestinalis|Rep: GLP_59_15138_16382 - Giardia lamblia
ATCC 50803
Length = 414
Score = 147 bits (357), Expect = 6e-34
Identities = 77/170 (45%), Positives = 102/170 (60%), Gaps = 3/170 (1%)
Query: 16 ILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVSSSG 75
+L Y GGEL+ +KK F E + AAQLVLA+EYLH ++V RDLKPEN+L+ ++G
Sbjct: 107 VLEYVPGGELFFHLKKKVTFDESYVKLVAAQLVLAIEYLHDMNIVIRDLKPENILLQANG 166
Query: 76 YIKLADFGFCKIIKSRTW---TLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAAF 132
YIK+ DFG K S T T+ GT EY +PE + + G+ VD WALG +IYE++
Sbjct: 167 YIKVTDFGLSKQNLSMTLGAKTMAGTSEYFSPEQVQNCGHGKGVDMWALGTIIYELLTGS 226
Query: 133 PPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLK 182
PPFYS + ++ KI+ Q K P K L+K LLE P R G K
Sbjct: 227 PPFYSDDKRAMFRKIIGEQPKMPSYFKDDLKDLLKGLLEKKPRSRLGCRK 276
>UniRef50_Q69G16 Cluster: Protein kinase C type beta; n=2;
Bilateria|Rep: Protein kinase C type beta - Schistosoma
mansoni (Blood fluke)
Length = 618
Score = 147 bits (357), Expect = 6e-34
Identities = 71/170 (41%), Positives = 105/170 (61%), Gaps = 3/170 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YF++ + GG+L I+K G F EP++ FYAA++ + L +LH DLK +N+L+
Sbjct: 363 LYFVMEFVNGGDLMFRIQKEGKFKEPIAVFYAAEVAVGLFFLHDSRNYLSDLKLDNLLLD 422
Query: 73 SSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
+ G+IK+ADFG CK T T CGTP+Y+APE++L K Y VDWW+ GVL+YEM+
Sbjct: 423 ADGHIKIADFGMCKDGITGDVTTHTFCGTPDYIAPEILLYKPYGKSVDWWSYGVLLYEML 482
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
A PPF + L+ IL P+++++ ++ K LL DP KR G
Sbjct: 483 AGQPPFEGEDEEDLFANILQHTISYPKSLSKESVSICKALLTRDPMKRLG 532
>UniRef50_A0DZB2 Cluster: Chromosome undetermined scaffold_7, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_7,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 379
Score = 147 bits (357), Expect = 6e-34
Identities = 71/193 (36%), Positives = 114/193 (59%), Gaps = 4/193 (2%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L + + +Y I+ + GGEL+ +K G +E ++FYAA++++ L+YLH ++++R
Sbjct: 113 LHYAFQSQTKLYLIMEFVPGGELFYHLKLQGRMTEKKTKFYAAEILIGLDYLHKQNIIYR 172
Query: 63 DLKPENVLVSSSGYIKLADFGFCKIIKSRTW---TLCGTPEYLAPELILSKGYSFPVDWW 119
DLKPEN+L+ S G+IKL DFG KI T+CGT EY+APE+I+ + YS DWW
Sbjct: 173 DLKPENILLDSEGHIKLCDFGLSKICYGNDMSAKTVCGTIEYIAPEVIIGQVYSKCCDWW 232
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
G L+Y+++ PPFY ++ E + P+ +++ L+K LL+ +P +R G
Sbjct: 233 TYGALLYDLLTGKPPFYRLSRKQIIEYATEKDIEIPQYLSEEATDLLKKLLKRNPRERLG 292
Query: 180 SLKAGVFRALEYP 192
LK E+P
Sbjct: 293 -LKRDAQEIYEHP 304
>UniRef50_Q1MX42 Cluster: Protein kinase C, delta V; n=9;
Euteleostomi|Rep: Protein kinase C, delta V - Mus
musculus (Mouse)
Length = 585
Score = 147 bits (356), Expect = 8e-34
Identities = 70/178 (39%), Positives = 109/178 (61%), Gaps = 5/178 (2%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
F KD+++ F++ + GG+L I+ G F + FYAA+++ L++LH +++RDL
Sbjct: 326 FQTKDHLF--FVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHSKGIIYRDL 383
Query: 65 KPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
K +NV++ G+IK+ADFG CK + R T CGTP+Y+APE++ YSF VDWW+
Sbjct: 384 KLDNVMLDRDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSVDWWSF 443
Query: 122 GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
GVL+YEM+ PF+ + +L+E I P +T+ K +++ L E DP KR G
Sbjct: 444 GVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFERDPDKRLG 501
>UniRef50_Q8MUA6 Cluster: Protein kinase C-related kinase; n=1;
Hydra vulgaris|Rep: Protein kinase C-related kinase -
Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 1030
Score = 147 bits (356), Expect = 8e-34
Identities = 72/179 (40%), Positives = 111/179 (62%), Gaps = 6/179 (3%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
F KD +V F++ Y GG+L I + FSEP + FY+ ++L L+YLH +V+RDL
Sbjct: 773 FQTKD--HVCFVMEYAPGGDLMMHIHE-EVFSEPRTIFYSGCVILGLQYLHEHDIVYRDL 829
Query: 65 KPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
K +N+L+ + GY+K+ADFG CK +T T CGTPE+LAPE++ Y+ VDWW L
Sbjct: 830 KLDNLLLDAEGYVKIADFGLCKEGMGFGQKTGTFCGTPEFLAPEVLTETSYTRAVDWWGL 889
Query: 122 GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
GVLI+EM+ PF + ++++ I+ + + P ++ AL++ LL +P +R GS
Sbjct: 890 GVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSNDSIALMRRLLRKNPERRLGS 948
>UniRef50_Q22RI5 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 394
Score = 147 bits (356), Expect = 8e-34
Identities = 73/203 (35%), Positives = 118/203 (58%), Gaps = 11/203 (5%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + + +Y ++ + GG+++ + K F E +FYAA++ LALE LH +V
Sbjct: 98 VQLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPFFPENKIKFYAAEIFLALEKLHEQGIV 157
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+LVS++G+IKL DFG K +KSR T++ CGT EY+APE+I +G+ D
Sbjct: 158 YRDLKPENILVSATGHIKLTDFGLSKKLKSRDEITYSFCGTAEYMAPEIISKQGHDVASD 217
Query: 118 WWAL--------GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNL 169
WW+ G ++YEM+ PPFY ++ +K++ + ++ C++L++ L
Sbjct: 218 WWSFFKYLNISKGAVLYEMLHGAPPFYEKNKERMMDKLVNQDVVIKDKYSKECQSLLRGL 277
Query: 170 LEVDPTKRYGSLKAGVFRALEYP 192
L D TKR G+ G +P
Sbjct: 278 LTRDKTKRLGNGPEGTQEIRNHP 300
>UniRef50_Q00078 Cluster: Protein kinase C-like; n=8;
Eurotiomycetidae|Rep: Protein kinase C-like - Aspergillus
niger
Length = 1096
Score = 147 bits (356), Expect = 8e-34
Identities = 71/171 (41%), Positives = 111/171 (64%), Gaps = 4/171 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
VYF++ Y +GG+L I++ G F +QFYAA+++LAL+Y H V++RDLK +N++++
Sbjct: 847 VYFVMEYISGGDLMLHIQR-GQFGLKRAQFYAAEVLLALKYFHENGVIYRDLKLDNIMLT 905
Query: 73 SSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G+IK+AD+G CK + T T CGTPE++APE++L K Y VDWWA GVLIY+M+
Sbjct: 906 LDGHIKVADYGLCKENMWYGATTSTFCGTPEFMAPEILLDKRYGRAVDWWAFGVLIYQML 965
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PF + ++Y+ IL + P +M + ++++ LL +P R GS
Sbjct: 966 LQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLLTREPELRLGS 1016
>UniRef50_Q91948 Cluster: PKN; n=3; Euteleostomi|Rep: PKN - Xenopus
sp. (clawed frog)
Length = 901
Score = 147 bits (355), Expect = 1e-33
Identities = 79/200 (39%), Positives = 118/200 (59%), Gaps = 7/200 (3%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
V F++ Y AGG+ T I FS+ + FYAA ++L L++LH ++V+RDLK +N+L+
Sbjct: 650 VCFVMDYMAGGDSMTHIHS-EVFSQSRAMFYAACVLLGLQFLHSRNIVYRDLKLDNLLLD 708
Query: 73 SSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
S GY+KLAD+G CK RT T CGTPE+LAPE++ Y+ VDWW GVLIYEM+
Sbjct: 709 SEGYVKLADYGLCKEGMGPSDRTSTFCGTPEFLAPEVLTDASYTRAVDWWGFGVLIYEMM 768
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFRAL 189
PF E ++++ I+ + + P +T A+++ LL +P +R G AG A
Sbjct: 769 VGESPFPGDEEEEVFDSIVNDEVRYPRFLTAEAIAIMRRLLRRNPERRLG---AGERDAE 825
Query: 190 EYPAEMAKQDFHRERVLSER 209
+ + +D E +LS R
Sbjct: 826 DVKKQPFFKDMDFEALLSRR 845
>UniRef50_Q23YB5 Cluster: Protein kinase domain containing protein;
n=8; Oligohymenophorea|Rep: Protein kinase domain
containing protein - Tetrahymena thermophila SB210
Length = 551
Score = 147 bits (355), Expect = 1e-33
Identities = 65/172 (37%), Positives = 106/172 (61%), Gaps = 4/172 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
++F+ + GGEL+ +K F E ++FY A++ LAL +LH S+++RDLKPEN+L+
Sbjct: 286 IFFVTQFMKGGELFQHLKHAKRFDENRARFYVAEIALALGHLHKKSIIYRDLKPENILMD 345
Query: 73 SSGYIKLADFGFCKIIKSR--TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIA 130
G+I L DFG KI++ + CGTPEYL+PE+I G++ DWWALG+ YEM+
Sbjct: 346 EHGHICLTDFGMAKIVRKNELAMSFCGTPEYLSPEIISGVGHTISCDWWALGIFTYEMLF 405
Query: 131 AFPPFYSSEPIKLYEKILTGQFKTPEN--MTQVCKALVKNLLEVDPTKRYGS 180
A PPFY+ ++++ I Q + P+ ++ + + + + DP +R G+
Sbjct: 406 ALPPFYTQNQDQMFKAIKESQIRFPDKIAISPEAQNFILSCCKKDPHQRLGT 457
>UniRef50_Q22LX8 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 679
Score = 147 bits (355), Expect = 1e-33
Identities = 70/209 (33%), Positives = 121/209 (57%), Gaps = 3/209 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL + + +Y ++ Y GG+L L+ + G EP+++ Y +++LALE LH+ ++V
Sbjct: 413 VSLKYAFQTKNKLYLVMDYCPGGDLDNLLFRKGRIPEPIAKIYICEIILALEALHNSNIV 472
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSKGYSFPVD 117
RDLKP NV++ G+ + DFG K R T + CG+ YL PE++ G++ +D
Sbjct: 473 FRDLKPSNVVLDKDGHACITDFGLAKQGMQRGDITKSFCGSLAYLPPEMLNKTGHTQSLD 532
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
W+ LGVL+YE++ PP+YS KL++ I K P+ + K+L+K LL DP +R
Sbjct: 533 WYLLGVLMYELLEGMPPYYSDNKQKLFDNIRNAPLKMPKQASDAAKSLLKGLLSKDPIQR 592
Query: 178 YGSLKAGVFRALEYPAEMAKQDFHRERVL 206
GS A ++ + ++ +D + +++L
Sbjct: 593 LGSKGAEEVKSHPFFRDVNWEDVYNKKLL 621
>UniRef50_O62570 Cluster: Protein kinase C-related kinase; n=1;
Suberites domuncula|Rep: Protein kinase C-related kinase
- Suberites domuncula (Sponge)
Length = 1102
Score = 147 bits (355), Expect = 1e-33
Identities = 71/172 (41%), Positives = 107/172 (62%), Gaps = 4/172 (2%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
+V F++ Y GG+L I + F EP + FYAA +VL L+YLH +V+RDLK +N+L+
Sbjct: 848 HVCFVMEYACGGDLMMHIHQ-DIFKEPRACFYAACVVLGLQYLHEKGIVYRDLKLDNLLL 906
Query: 72 SSSGYIKLADFGFCKIIK---SRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEM 128
GY+K+ADFG CK +RT T CGTPE+LAPE++ Y+ VDWW LGVLIYEM
Sbjct: 907 DKDGYVKIADFGLCKEGMWHGTRTSTFCGTPEFLAPEVLTDVSYTRAVDWWGLGVLIYEM 966
Query: 129 IAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
+ PF + ++++ I+ + P ++ ++++ LL +P KR G+
Sbjct: 967 LVGESPFPGEDEEEVFDSIVNDDVRYPRFLSSEAISIMRKLLRRNPEKRLGA 1018
>UniRef50_A0C3V8 Cluster: Chromosome undetermined scaffold_148,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_148,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 372
Score = 147 bits (355), Expect = 1e-33
Identities = 69/184 (37%), Positives = 116/184 (63%), Gaps = 4/184 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLH-HCSV 59
+ L + + + YF++ Y +GG+L+ ++KK G E + +F A+++LALEYLH +
Sbjct: 108 VKLRYAFQTSSRCYFVMDYISGGDLHRVLKKNGALPEKVVKFLVAEIILALEYLHTQLKI 167
Query: 60 VHRDLKPENVLVSSSGYIKLADFGFCKIIKSR-TWTLCGTPEYLAPELILSKGYSFPVDW 118
++RDLKPEN+L++ +G+IKL DFG IK T+T+ GTPEYLAPE+I G+++ VD+
Sbjct: 168 IYRDLKPENILLTETGHIKLTDFGLATYIKDEHTYTIAGTPEYLAPEIIARSGHTYEVDF 227
Query: 119 WALGVLIYEMIAAFPPFYSSE--PIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTK 176
W LG+LIYEM++ PF + + I+ + ++ ++L+ +LL +P +
Sbjct: 228 WTLGILIYEMLSGQAPFTCEDRNVCTIQNLIMQNKPIYSPKISSNARSLISSLLRFNPKE 287
Query: 177 RYGS 180
R G+
Sbjct: 288 RLGA 291
>UniRef50_A0BWJ4 Cluster: Chromosome undetermined scaffold_132,
whole genome shotgun sequence; n=5; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_132,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 947
Score = 147 bits (355), Expect = 1e-33
Identities = 68/185 (36%), Positives = 117/185 (63%), Gaps = 5/185 (2%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
+V F L Y GGEL+ +K++ E ++FY +Q+ LA+ +LH +++RD+KPEN+L+
Sbjct: 529 WVCFALEYCPGGELFQQLKRVKRMDEQQAKFYFSQVCLAIHHLHENGIIYRDIKPENILI 588
Query: 72 SSSGYIKLADFGFCK-IIKS--RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEM 128
G IKLADFG + +K ++ CG+PEY+APE++L G+++ +D + LG L+YE+
Sbjct: 589 DQDGNIKLADFGLARPNMKDDLLAFSFCGSPEYMAPEMLLKSGHNYQIDHYCLGALLYEL 648
Query: 129 IAAFPPFYSSEPIKLYEKILTGQFKTP-ENMTQVCKALVKNLLEVDPTKRYGSLKAGVFR 187
+ PP+YS+ P ++Y+ IL P +N + + L++ LL+ D R G + G++
Sbjct: 649 LTGLPPYYSNNPEQIYKNILQHDLTLPNKNCSAESRDLMQKLLQKDVFNRLGK-EYGIYE 707
Query: 188 ALEYP 192
L++P
Sbjct: 708 ILKHP 712
>UniRef50_P36583 Cluster: Protein kinase C-like 2; n=1;
Schizosaccharomyces pombe|Rep: Protein kinase C-like 2 -
Schizosaccharomyces pombe (Fission yeast)
Length = 1016
Score = 147 bits (355), Expect = 1e-33
Identities = 69/171 (40%), Positives = 113/171 (66%), Gaps = 4/171 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YF++ + +GG+L I++ FS +QFYAA++ LAL+Y H +++RDLK +N+L+S
Sbjct: 759 IYFVMDFVSGGDLMLHIQQ-EQFSRRRAQFYAAEVCLALKYFHDNGIIYRDLKLDNILLS 817
Query: 73 SSGYIKLADFGFCKIIK---SRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G++K+AD+G CK + T T CGTPE++APE++L + Y+ VDWWA GVLIY+M+
Sbjct: 818 PDGHVKVADYGLCKEDMWHDNTTATFCGTPEFMAPEILLEQQYTRSVDWWAFGVLIYQML 877
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PF + ++++ IL+ + P +M + ++++ LL DP KR GS
Sbjct: 878 LGQSPFRGEDEEEIFDAILSDEPLYPIHMPRDSVSILQQLLTRDPKKRLGS 928
>UniRef50_P36582 Cluster: Protein kinase C-like 1; n=2;
Schizosaccharomyces pombe|Rep: Protein kinase C-like 1 -
Schizosaccharomyces pombe (Fission yeast)
Length = 988
Score = 147 bits (355), Expect = 1e-33
Identities = 69/171 (40%), Positives = 110/171 (64%), Gaps = 4/171 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
VYF++ Y GG+L I++ FS ++FY A++ LAL+Y H + +RDLK +N+L+
Sbjct: 740 VYFVMEYILGGDLMVHIQRQQ-FSVKRARFYGAEVCLALKYFHENGIAYRDLKLDNILLC 798
Query: 73 SSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G+I++AD+G CK ++ + T T CGTPE++APE++L + YS VDWWA GVL+Y+M+
Sbjct: 799 PDGHIRIADYGLCKENMLLGNTTSTFCGTPEFMAPEILLEQQYSKDVDWWAFGVLMYQML 858
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PF + ++++ IL+ + P NM +L++ LL DP +R GS
Sbjct: 859 LGQSPFKGEDEEEIFDAILSDEPLFPINMPADAVSLLRGLLTRDPNQRLGS 909
>UniRef50_UPI00006CC8B4 Cluster: Protein kinase domain containing
protein; n=2; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 464
Score = 146 bits (354), Expect = 1e-33
Identities = 73/184 (39%), Positives = 114/184 (61%), Gaps = 6/184 (3%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L ++ ++ ++ IL Y +GG+L+ I K SE ++FYAAQ+VL LEYLH ++V+R
Sbjct: 103 LHYSFQNQNNLFLILDYCSGGDLFNYISKKNTISEKDAKFYAAQIVLMLEYLHSQNIVYR 162
Query: 63 DLKPENVLVSSSGYIKLADFGFCK--IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
DLKPEN+L+ +GY+KL DFG+ + + ++CGTP Y PE+I +G+ PVDWWA
Sbjct: 163 DLKPENILIEKNGYLKLGDFGYARQNMDSIEAKSVCGTPHYFPPEMITREGHGKPVDWWA 222
Query: 121 LGVLIYEMIAAFPPFYSSEPIKLYEKILTGQ--FKTPEN--MTQVCKALVKNLLEVDPTK 176
LG +IYEM+ PF S L+++I F+ +N ++ K +V LL+ + +
Sbjct: 223 LGCVIYEMVFGATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKLLKKNQNE 282
Query: 177 RYGS 180
R G+
Sbjct: 283 RLGT 286
>UniRef50_UPI0000499007 Cluster: hypothetical protein 139.t00021;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 139.t00021 - Entamoeba histolytica HM-1:IMSS
Length = 982
Score = 146 bits (354), Expect = 1e-33
Identities = 82/246 (33%), Positives = 140/246 (56%), Gaps = 18/246 (7%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + +D++ +Y ++ Y GG+L TL++ +G F+E ++ Y+A+++L+L Y+H V
Sbjct: 675 VKLYYAFQDDINLYLVMEYCPGGDLATLLEHIGSFNEYVAHVYSAEILLSLHYIHALGCV 734
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK--IIKSRTWTLCG---TPEYLAPELILSKGYSFP 115
H+D+KP+N+L++ +G++ L DFG ++ T G TP+Y APE+++S YSF
Sbjct: 735 HKDIKPDNILINRNGHLVLTDFGLSSYGLVSQETAGKTGIFCTPDYAAPEILISNSYSFA 794
Query: 116 VDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPE--NMTQVCKALVKNLLEVD 173
D++ALG ++YE + +PPF +S P ++ KI G ++ PE +++ CK LV LL +
Sbjct: 795 SDYFALGCMLYEFVVGYPPFNASTPEAIFMKIQQGVYEWPEDVDVSDDCKDLVSKLLCPE 854
Query: 174 PTKRYGSLKAGVFRALEYPAEMAKQDFHRERVLSERWNLIRFVAQ--WTNGTEYFNGVEE 231
P KR VF+ +E + D H + + E I FV Q N T YF
Sbjct: 855 PEKR------PVFKQIENHPFFS--DIHWDTLFDESREDI-FVPQLDGDNDTGYFEDERG 905
Query: 232 LLSHHL 237
+ H+
Sbjct: 906 MKQSHM 911
>UniRef50_UPI000065FF34 Cluster: Homolog of Homo sapiens "Protein
kinase C, epsilon type; n=3; Clupeocephala|Rep: Homolog
of Homo sapiens "Protein kinase C, epsilon type -
Takifugu rubripes
Length = 808
Score = 146 bits (354), Expect = 1e-33
Identities = 72/174 (41%), Positives = 107/174 (61%), Gaps = 3/174 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
++F++ Y GG+L I++ F E S+FYAA++ AL +LH V++RDLK +N+L+
Sbjct: 560 LFFVMEYVNGGDLMFQIQRSRKFDEARSRFYAAEVTSALMFLHRHGVIYRDLKLDNILLD 619
Query: 73 SSGYIKLADFGFCK--IIKS-RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
+ G+ KLADFG CK I+ T T CGTP+Y+APE++ Y VDWWALGVL+YEM+
Sbjct: 620 ADGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELDYGPSVDWWALGVLMYEMM 679
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKA 183
A PPF + L+E IL P +++ +++K + P KR G + A
Sbjct: 680 AGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKSPNKRLGCVVA 733
>UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative;
n=2; Ostreococcus|Rep: CGMP-dependent protein kinase,
putative - Ostreococcus tauri
Length = 935
Score = 146 bits (354), Expect = 1e-33
Identities = 74/195 (37%), Positives = 114/195 (58%), Gaps = 3/195 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGG-FSEPLSQFYAAQLVLALEYLHHCSV 59
++L T + ++ ++ GGEL+T ++ E +FYAA +V A EYLH ++
Sbjct: 683 VNLHRTYVNEKSIFMLMDKVLGGELFTYLQMRNAPLPEAHGKFYAACVVSAFEYLHDRNI 742
Query: 60 VHRDLKPENVLVSSSGYIKLADFGFCKIIKS--RTWTLCGTPEYLAPELILSKGYSFPVD 117
++RDLKPEN+L+S++GY+K+ DF F K ++ +T+TLCGTP+YLAPE + G++ VD
Sbjct: 743 IYRDLKPENLLISTNGYLKVTDFSFAKKLQKGQKTFTLCGTPQYLAPEQVQQVGHNRAVD 802
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WWALGVLIYE++ PPF + Y+ I F +++V LL P R
Sbjct: 803 WWALGVLIYELVNGLPPFNQDDDYARYKAINDVSFHFSPKNAPAFRSVVSGLLLRLPAGR 862
Query: 178 YGSLKAGVFRALEYP 192
G K+G ++P
Sbjct: 863 LGMGKSGARDIKQHP 877
>UniRef50_A2EY79 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 716
Score = 146 bits (354), Expect = 1e-33
Identities = 70/178 (39%), Positives = 115/178 (64%), Gaps = 10/178 (5%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+Y ++ Y GG+L++L++K G F E +++ Y AQ+V ALEYL +V+HRDLKP+N+L+
Sbjct: 397 LYMVMEYLPGGDLFSLLEKFGCFPEDVARNYTAQIVAALEYLRQNNVIHRDLKPDNILLD 456
Query: 73 SSGYIKLADFG--FCKIIKSRT----WTLCGTPEYLAPELILSKGYSFPVDWWALGVLIY 126
S+G++KL DFG + ++ +T T GTP+Y+APE+I + +S+ D+W+LG ++Y
Sbjct: 457 SAGHLKLVDFGLSYFGVVGRQTDTHESTALGTPDYIAPEIITLENHSYQADYWSLGAMLY 516
Query: 127 EMIAAFPPFYSSEPIKLYEKILTG--QFKTPE--NMTQVCKALVKNLLEVDPTKRYGS 180
E I PF+ + P +++ +L G FK E N ++ C ++ LL DP KR G+
Sbjct: 517 EFITGVAPFHDNTPQEIFSNVLCGSINFKELEEMNASKDCIDFIQKLLVSDPKKRLGA 574
>UniRef50_A0DVL2 Cluster: Chromosome undetermined scaffold_66, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_66,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 488
Score = 146 bits (354), Expect = 1e-33
Identities = 67/192 (34%), Positives = 122/192 (63%), Gaps = 4/192 (2%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L++ + ++ FI + AGG+L ++K F+E ++FY + +L L YLH +++R
Sbjct: 192 LEYALECPNHLIFITEFCAGGDLLYYLQKYHVFTETQARFYIIEFILGLIYLHQLDIIYR 251
Query: 63 DLKPENVLVSSSGYIKLADFGFCKIIKSR-TWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
D+KPEN+L+ +G+I++ADFG K ++ ++ CG+PEY+APE++ ++G++ +D + L
Sbjct: 252 DIKPENILIDITGHIQIADFGLAKPTRNEYAYSFCGSPEYMAPEMLTNQGHNQQLDHYCL 311
Query: 122 GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN--MTQVCKALVKNLLEVDPTKRYG 179
GVL+YE++ PPFYS + K+YE I+ + + P+N ++ K L+ LL+ D R G
Sbjct: 312 GVLLYELVVGQPPFYSEDINKIYENIILKEVEFPKNNTLSNEIKDLIVRLLDKDQKSRIG 371
Query: 180 SLKAGVFRALEY 191
+ G+ L++
Sbjct: 372 H-QGGLLEILDH 382
>UniRef50_P43057 Cluster: Protein kinase C-like 1; n=4;
Saccharomycetales|Rep: Protein kinase C-like 1 - Candida
albicans (Yeast)
Length = 1097
Score = 146 bits (354), Expect = 1e-33
Identities = 68/183 (37%), Positives = 113/183 (61%), Gaps = 4/183 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YF++ Y +GG+L I+K F+ ++FYA +++L L+Y H +V+RDLK +N+L++
Sbjct: 846 IYFVMEYISGGDLMWHIQK-NRFTAKRAKFYACEVLLGLKYFHDNGIVYRDLKLDNILLT 904
Query: 73 SSGYIKLADFGFCKII---KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
+ G+IK+ D+G CK KS T T CGTPE++APE++ K Y VDWWA GVL+++M+
Sbjct: 905 TKGHIKIGDYGLCKEDMWHKSTTSTFCGTPEFMAPEIVAGKAYDRSVDWWAFGVLLFQML 964
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFRAL 189
PF + ++ I + K P N+++ +++ LL DP++R GS +
Sbjct: 965 LCQSPFKGDDEDDIFNAIENDEVKYPINLSRQTVLVLQALLTKDPSQRLGSGPKDAEEIM 1024
Query: 190 EYP 192
E+P
Sbjct: 1025 EHP 1027
>UniRef50_UPI00006607B3 Cluster: RAC-beta serine/threonine-protein
kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase
Akt-2) (Protein kinase B, beta) (PKB beta).; n=1;
Takifugu rubripes|Rep: RAC-beta serine/threonine-protein
kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase
Akt-2) (Protein kinase B, beta) (PKB beta). - Takifugu
rubripes
Length = 518
Score = 145 bits (352), Expect = 2e-33
Identities = 69/148 (46%), Positives = 97/148 (65%), Gaps = 3/148 (2%)
Query: 35 FSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVSSSGYIKLADFGFCK--IIKSRT 92
F+E ++FY A++V ALEYLH VV+RDLK EN+++ G+IK+ DFG CK I T
Sbjct: 284 FTEDRARFYGAEIVSALEYLHSRDVVYRDLKLENLMLDKDGHIKITDFGLCKEGITPDAT 343
Query: 93 W-TLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQ 151
T CGTPEYLAPE++ Y VDWW LGV++YEM+ PFY+ + +L+E IL +
Sbjct: 344 MKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEE 403
Query: 152 FKTPENMTQVCKALVKNLLEVDPTKRYG 179
+ P N++ K+L+ LL+ DP +R G
Sbjct: 404 IRFPRNLSPEAKSLLAGLLKKDPKQRLG 431
>UniRef50_Q584T1 Cluster: Rac serine-threonine kinase, putative;
n=5; Trypanosoma|Rep: Rac serine-threonine kinase,
putative - Trypanosoma brucei
Length = 458
Score = 145 bits (352), Expect = 2e-33
Identities = 72/188 (38%), Positives = 115/188 (61%), Gaps = 11/188 (5%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL + + +Y ++ + +GGEL+ ++ + F E ++FY ++ LAL YLH ++
Sbjct: 195 VSLHYAFQTKGSLYLVMDFLSGGELFFHLESVSVFDEWRAKFYCGEIALALGYLHAQDII 254
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK--IIKSRTWTLCGTPEYLAPELILSKGYSFPVDW 118
+RDLKPEN ++ + G++ L DFG K + + +T CGTPEY+APE +L K + VDW
Sbjct: 255 YRDLKPENAVLDADGHVCLTDFGLAKMDVRDACNFTFCGTPEYIAPEFLLGKPHGKAVDW 314
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTG--QFKTPE----NMTQV---CKALVKNL 169
W+LG+L+YEM+ PPFYS +Y+KIL+ QF E NM Q+ + L++ L
Sbjct: 315 WSLGILLYEMLEGIPPFYSENVSAMYDKILSSELQFGDGEGGSNNMPQISEEAQDLLRRL 374
Query: 170 LEVDPTKR 177
L+ +P R
Sbjct: 375 LDRNPDTR 382
>UniRef50_A2DB15 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 425
Score = 145 bits (352), Expect = 2e-33
Identities = 71/180 (39%), Positives = 109/180 (60%), Gaps = 3/180 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L F+ + Y +L Y +GG+L++ ++ G F+ + Y A+L +A+ +LH S++
Sbjct: 168 IKLLFSFQSPSKFYLVLEYSSGGDLFSHLRNSGRFTLDDIKIYIAELAVAIHHLHKNSII 227
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPENVL + G++KL DFG KI+K T T+CGT EY+APE IL Y + VD
Sbjct: 228 YRDLKPENVLFCADGHLKLTDFGISKILKQHSDTTSTMCGTKEYIAPEEILGNQYGYAVD 287
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW LG+L+YE+IA PF + L++ IL+ K+L+ +LL+ DP +R
Sbjct: 288 WWQLGILLYEIIARHTPFANENTQTLFKNILSRNVALFPIRDPGAKSLIGHLLKKDPKER 347
>UniRef50_A0DPW4 Cluster: Chromosome undetermined scaffold_6, whole
genome shotgun sequence; n=6; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_6,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 391
Score = 145 bits (352), Expect = 2e-33
Identities = 74/184 (40%), Positives = 120/184 (65%), Gaps = 7/184 (3%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLG-GFSEPLSQFYAAQLVLALEYLH-HCSVV 60
L + + N ++YF++ AGGE Y ++ ++ G E + +F A++VLALEYL+ V+
Sbjct: 126 LKYAFQTNSHIYFVMENIAGGEFYKILSQVKTGLPENVVKFVGAEVVLALEYLNTKLKVI 185
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKS---RTWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L++++G++KL DFG + + +++T+ GT EYLAPE++ G+S+ VD
Sbjct: 186 YRDLKPENLLLTTTGHVKLTDFGLATMRRENGEKSYTVAGTAEYLAPEIVNKSGHSYEVD 245
Query: 118 WWALGVLIYEMIAAFPPFY-SSEPIK-LYEKILTGQFKTPENMTQVCKALVKNLLEVDPT 175
W LG+LIYEMI F PF S+ K + +KI+ Q PE M+ L+K +L+ +P+
Sbjct: 246 IWTLGILIYEMINGFTPFRDSNNDFKVISQKIIENQPIYPEKMSPQSVDLIKQILQTNPS 305
Query: 176 KRYG 179
+R G
Sbjct: 306 ERLG 309
>UniRef50_A0BSF2 Cluster: Chromosome undetermined scaffold_125,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_125,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 325
Score = 145 bits (352), Expect = 2e-33
Identities = 74/169 (43%), Positives = 105/169 (62%), Gaps = 3/169 (1%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
+ YF+ Y GG+L++L K G F E QFYA ++ AL++LH +++RDLKP+N+L+
Sbjct: 81 HFYFVSEYCVGGDLFSLFKAKGKFKEKHIQFYAILIIHALQFLHTQKIIYRDLKPKNILI 140
Query: 72 SSSGYIKLADFGFCKIIKSR-TWTLCGTPEYLAPELI--LSKGYSFPVDWWALGVLIYEM 128
GYIKL DFG KI++ T + GT EYLAPE++ + GY + VD W+LG L+YE+
Sbjct: 141 DEKGYIKLTDFGLSKILQQEMTEQVQGTLEYLAPEILNQIGDGYDYKVDCWSLGCLLYEL 200
Query: 129 IAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
IA PPF S + KL I T Q K ++ K L+ LL+ DP +R
Sbjct: 201 IAECPPFMSEQRDKLISLIKTTQPKFNFPISDELKDLIIRLLQKDPNQR 249
>UniRef50_Q86ZV2 Cluster: Protein kinase C; n=1; Pichia
pastoris|Rep: Protein kinase C - Pichia pastoris (Yeast)
Length = 1035
Score = 145 bits (352), Expect = 2e-33
Identities = 70/171 (40%), Positives = 110/171 (64%), Gaps = 4/171 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YF++ Y +GG+L ++ FS ++FYAA+++LAL+Y H VV+RDLK +N+L++
Sbjct: 785 IYFVMEYVSGGDLMWHAQQRT-FSPSRAKFYAAEVLLALQYFHENGVVYRDLKLDNILLT 843
Query: 73 SSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
+ G+IKLAD+G CK S T T CGTPE++APE++ + Y VDWWA GVL+Y+M+
Sbjct: 844 ADGHIKLADYGLCKEEMWYGSTTATFCGTPEFMAPEILKEQKYDKAVDWWAFGVLLYQMM 903
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PF + +++ ILT + + P M + +++ LL DP KR G+
Sbjct: 904 LGKSPFKGEDEDEVFNSILTDEPRYPIQMDRESVDILQQLLTKDPYKRLGA 954
>UniRef50_UPI0000499868 Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 441
Score = 144 bits (350), Expect = 4e-33
Identities = 69/176 (39%), Positives = 111/176 (63%), Gaps = 5/176 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L ++ + ++++++ Y GGELY + + F E +QFY +Q++LALE LH +++
Sbjct: 179 VNLYYSFQSATHLHYVIDYCPGGELYYRLIQEKSFCESRTQFYISQVILALECLHQMNII 238
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKS---RTWTLCGTPEYLAPELILSKGYSFPVD 117
+RD+K ENVL+ GY++L DFG K S T T CGTPEYL+PE++L++ Y+ +D
Sbjct: 239 YRDVKLENVLICEDGYLRLTDFGLSKENVSGNETTATFCGTPEYLSPEVVLAEPYTNVID 298
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQ--FKTPENMTQVCKALVKNLLE 171
WW +G++ YEM+ PF S +LY+KIL F T ++ VCK + +LE
Sbjct: 299 WWGVGIMTYEMMHGQAPFISDNIQQLYQKILYSPVIFPTTSPVSAVCKDFITKMLE 354
>UniRef50_A2D9C1 Cluster: AGC family protein kinase; n=4;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 474
Score = 144 bits (350), Expect = 4e-33
Identities = 71/179 (39%), Positives = 105/179 (58%), Gaps = 2/179 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L F + Y L Y GGEL+ +++ G + Y A+++LAL +LH V+
Sbjct: 170 VNLKFAFQSPSKFYLGLEYVPGGELFFHMQRYGNIRLDDCKIYIAEILLALNHLHSLGVI 229
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKII--KSRTWTLCGTPEYLAPELILSKGYSFPVDW 118
+RDLKPEN+L+ ++G+IKL DFG K + + T T CGT EYLAPE++ + Y++ VDW
Sbjct: 230 YRDLKPENILLDANGHIKLTDFGLSKNLAHEVHTSTFCGTTEYLAPEVVNHQPYTYSVDW 289
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WALGVL YE++ PF K++ IL + + P N Q +K +L DP KR
Sbjct: 290 WALGVLTYELLFGTTPFAHQNRAKMFRNILDNEPQFPPNFNQEAIDFIKAMLTKDPLKR 348
>UniRef50_Q6AX33 Cluster: Microtubule-associated
serine/threonine-protein kinase 3; n=9; Tetrapoda|Rep:
Microtubule-associated serine/threonine-protein kinase 3
- Xenopus laevis (African clawed frog)
Length = 1482
Score = 144 bits (350), Expect = 4e-33
Identities = 105/299 (35%), Positives = 157/299 (52%), Gaps = 48/299 (16%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
++ ++ Y GG+ TL+K +G +S+ Y A+ VLALEYLH+ +VHRDLKP+N+L+
Sbjct: 471 HLCMVMEYVEGGDCATLLKNMGPLPVDMSRMYFAETVLALEYLHNYGIVHRDLKPDNLLI 530
Query: 72 SSSGYIKLADFGFCKI-IKSRTWTL-----------------CGTPEYLAPELILSKGYS 113
+S G+IKL DFG K+ + + T L CGTPEY+APE+IL +GY
Sbjct: 531 TSLGHIKLTDFGLSKVGLMNMTTNLYEGHIEKDTREFLDKQVCGTPEYIAPEVILRQGYG 590
Query: 114 FPVDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTP---ENMTQVCKALVKNLL 170
PVDWWA+G+++YE + PF+ P +L+ ++++ P E + + L+ LL
Sbjct: 591 KPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDIIWPGGEEALPADSQDLITRLL 650
Query: 171 EVDPTKRYGSLKAGVFRALEYPAEMAKQDFHRERVLSERWN-LIR----FVAQW--TNGT 223
+ +R G+ A E+ + F LS WN L+R FV Q + T
Sbjct: 651 RQNSLERLGTGGA---------QEVKQHTF----FLSLDWNGLLRQKAEFVPQLEADDDT 697
Query: 224 EYFNGVEELLSHHLAIYEKVLEEASSDGISLEVEKNFPPTEERWSILQAVFFSSTVLTT 282
YF+ E HHLA E EE + D S+E+ + F R+S V+ SS L T
Sbjct: 698 SYFDTRSERY-HHLASEED--EETNDDESSVEI-RQFSSCSHRFS---KVYSSSEHLAT 749
>UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, whole
genome shotgun sequence; n=5; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_76,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 864
Score = 144 bits (349), Expect = 5e-33
Identities = 70/189 (37%), Positives = 111/189 (58%), Gaps = 10/189 (5%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KD Y+YF++ + G EL+ I+++G + SQFY L++ +EYLH +++RD+KPE
Sbjct: 563 KDQNYIYFLVEFIKGMELFDAIREIGLLTTSDSQFYIGSLLICVEYLHKLQIIYRDIKPE 622
Query: 68 NVLVSSSGYIKLADFGFCKIIKS---RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVL 124
N++V GY+++ D G K + RT+T+ GTP Y+APE+I KGY+F VD W++GV
Sbjct: 623 NIMVDEKGYLRMIDMGTAKFLNQKSIRTYTIIGTPHYMAPEIITGKGYTFSVDLWSIGVC 682
Query: 125 IYEMIAAFPPFY--SSEPIKLYEKILTGQFKTPENM-TQVCKALVKNLLEVDPTKR---- 177
+YE + P+ + +P ++YE+I P M + K ++ LL P R
Sbjct: 683 LYEFMCGGVPYAEDADDPYEIYEEIQKKSITFPTFMKDKKAKKFIEQLLSKTPEARLGGG 742
Query: 178 YGSLKAGVF 186
Y SLKA +
Sbjct: 743 YASLKANTW 751
>UniRef50_A0DUX2 Cluster: Chromosome undetermined scaffold_65, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_65,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 371
Score = 144 bits (349), Expect = 5e-33
Identities = 66/183 (36%), Positives = 112/183 (61%), Gaps = 3/183 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + + + +Y ++ + GGEL+ ++K F E QFYAA+L++A++ LH +++
Sbjct: 117 VKLHYAFQSHSRLYMVMDFMQGGELFLHLRKRFKFPEDWVQFYAAELLVAIDLLHQSNII 176
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPEN+L+ +G+I L DFG K+ T++ CGTPEY+APE++ +G++F VD
Sbjct: 177 YRDLKPENILLDKNGHIVLTDFGLSKLGFEKNEMTYSFCGTPEYVAPEILYQRGHTFVVD 236
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
+++ G +IYEM+ PPFYS + ++ + + + +L+K LL DP R
Sbjct: 237 FYSYGAMIYEMLCGSPPFYSKDKREMLKNRCEKPLEMKSCFSFYAASLLKGLLTKDPGLR 296
Query: 178 YGS 180
GS
Sbjct: 297 LGS 299
>UniRef50_Q00X68 Cluster: Cyclic nucleotide dependent protein
kinase; n=3; Eukaryota|Rep: Cyclic nucleotide dependent
protein kinase - Ostreococcus tauri
Length = 1179
Score = 144 bits (348), Expect = 7e-33
Identities = 71/180 (39%), Positives = 112/180 (62%), Gaps = 7/180 (3%)
Query: 8 KDNMYVYFILPYEAGGELYTLIK----KLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRD 63
+D +Y ++ Y GG+L+ L+ + G F ++QFYAA++ +ALEY+H V+RD
Sbjct: 476 QDARSLYLLMDYLPGGDLFQLLVSGPYRGGRFPVNVAQFYAAEVFIALEYIHTEEYVYRD 535
Query: 64 LKPENVLVSSSGYIKLADFGFCK--IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
LKPENVL+ + G++KL DFGFC+ + R +T CGT +Y+APE++L++GY D+W+
Sbjct: 536 LKPENVLLDACGHVKLTDFGFCRHLLPGERAYTTCGTADYMAPEVMLAQGYDQLADYWSF 595
Query: 122 GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN-MTQVCKALVKNLLEVDPTKRYGS 180
GVL+YEM+ + PF S + +I++ K + K+L+ L VD +KR GS
Sbjct: 596 GVLLYEMLVGYAPFASVSDGVRHRRIISSDLKFHSTYFSLTAKSLISRLCVVDVSKRLGS 655
>UniRef50_Q22S16 Cluster: Protein kinase domain containing protein;
n=5; Oligohymenophorea|Rep: Protein kinase domain
containing protein - Tetrahymena thermophila SB210
Length = 384
Score = 144 bits (348), Expect = 7e-33
Identities = 71/175 (40%), Positives = 105/175 (60%), Gaps = 8/175 (4%)
Query: 14 YFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVSS 73
Y ++ GGEL+ I + +SE + +V A+ Y H + HRDLKPEN+L +S
Sbjct: 155 YMVMELMTGGELFDRIVEKEFYSEKEACDVIKPIVDAINYCHKMGIAHRDLKPENLLYTS 214
Query: 74 ---SGYIKLADFGFCKIIKSRTWTL-CGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
IK++DFG K+I T CGTP Y+APE++ KGY+F VD+W++GV++Y ++
Sbjct: 215 PDPDATIKISDFGLAKVISDELMTTACGTPSYIAPEILEGKGYTFAVDYWSIGVILYVLL 274
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTP----ENMTQVCKALVKNLLEVDPTKRYGS 180
FPPFY KL+ I GQF+ P + ++ K L+KNLL+VDP +RY +
Sbjct: 275 CGFPPFYEDTNEKLFAMIKKGQFEFPSPQWDPISNQAKDLIKNLLKVDPKQRYNA 329
>UniRef50_A0BN99 Cluster: Chromosome undetermined scaffold_118,
whole genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_118,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 562
Score = 144 bits (348), Expect = 7e-33
Identities = 70/183 (38%), Positives = 113/183 (61%), Gaps = 5/183 (2%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L ++ + Y+ F++ Y AGGEL+ ++K SEPL++ Y Q+ LA+ LH +V+R
Sbjct: 223 LFYSFETKFYLVFVMEYCAGGELFYHLRKWKRLSEPLAKQYFVQVCLAINELHKFGIVYR 282
Query: 63 DLKPENVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSKGYSFPVDWW 119
D+KPEN+L+ GYI+L+DFG K +R ++ CG+PEY++PE++ +G+++ VD +
Sbjct: 283 DIKPENILLDLDGYIRLSDFGLSKPNMNRDETAYSFCGSPEYMSPEMLKREGHNYMVDIY 342
Query: 120 ALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTP--ENMTQVCKALVKNLLEVDPTKR 177
LG L+YE I PPFY ++Y IL + + P +++ K L+ LL DP KR
Sbjct: 343 CLGALLYEFIFGSPPFYCRNIDQIYNSILNDKLQFPPFKDINPDLKDLISKLLIKDPAKR 402
Query: 178 YGS 180
G+
Sbjct: 403 LGA 405
>UniRef50_P24723 Cluster: Protein kinase C eta type; n=44;
Eumetazoa|Rep: Protein kinase C eta type - Homo sapiens
(Human)
Length = 682
Score = 144 bits (348), Expect = 7e-33
Identities = 70/175 (40%), Positives = 106/175 (60%), Gaps = 3/175 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
++F++ + GG+L I+K F E ++FYAA+++ AL +LH +++RDLK +NVL+
Sbjct: 428 LFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLD 487
Query: 73 SSGYIKLADFGFCK--IIKS-RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G+ KLADFG CK I T T CGTP+Y+APE++ Y VDWWA+GVL+YEM+
Sbjct: 488 HEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEML 547
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAG 184
PF + L+E IL + P + + ++K+ + +PT R GSL G
Sbjct: 548 CGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLTQG 602
>UniRef50_A0E1G0 Cluster: Chromosome undetermined scaffold_73, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_73,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 371
Score = 143 bits (347), Expect = 1e-32
Identities = 71/188 (37%), Positives = 120/188 (63%), Gaps = 8/188 (4%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKL--GGFSEPLSQFYAAQLVLALEYLHHC- 57
+ L ++ + +Y ++ + GG+L +++K G F+E ++F AA+++L L+Y+H+
Sbjct: 104 VKLKYSFQTEQKLYLVMEFIKGGQLAKVLRKRQSGRFTEEQTRFCAAEIILGLQYMHNTL 163
Query: 58 SVVHRDLKPENVLVSSSGYIKLADFGFCKIIKS---RTWTLCGTPEYLAPELILSKGYSF 114
V++RDLKPENV+V+ G++KL DFG K ++ + +TL GTPEYLAPE+++++G++
Sbjct: 164 RVIYRDLKPENVMVTEEGHLKLTDFGLSKQYETEEAKFFTLAGTPEYLAPEILVNQGHNH 223
Query: 115 PVDWWALGVLIYEMIAAFPPFYSSE--PIKLYEKILTGQFKTPENMTQVCKALVKNLLEV 172
VD+W LGVLIYEM+ PFY + + I Q K P +++ K++V LL
Sbjct: 224 MVDFWCLGVLIYEMLVGETPFYDCQRNHNTIEHNIKNAQIKYPNFLSEQSKSIVDRLLNK 283
Query: 173 DPTKRYGS 180
DP +R G+
Sbjct: 284 DPKQRLGA 291
>UniRef50_A0DUI6 Cluster: Chromosome undetermined scaffold_64, whole
genome shotgun sequence; n=3; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_64, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 314
Score = 143 bits (347), Expect = 1e-32
Identities = 72/179 (40%), Positives = 105/179 (58%), Gaps = 9/179 (5%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
+D+ Y Y +L GGEL+ I + FSE + ++ AL Y H +VHRDLKPE
Sbjct: 78 EDDTYFYMVLELMTGGELFERIVEKDHFSEKEAAATLRPIIDALAYCHKMGIVHRDLKPE 137
Query: 68 NVLVSS---SGYIKLADFGFCKIIKSRT--WTLCGTPEYLAPELILSKGYSFPVDWWALG 122
N+L S+ +K++DFG + + S T CGTP Y+APE+I KGY+ +D+W++G
Sbjct: 138 NLLYSTMEPGALLKVSDFGLARFVGSEEVMMTQCGTPGYVAPEIINGKGYTEAIDFWSVG 197
Query: 123 VLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTP----ENMTQVCKALVKNLLEVDPTKR 177
V++Y M+ FPPFY + KL+ I TG F P + ++ K L+K LL +DP KR
Sbjct: 198 VILYIMLCGFPPFYDEDNDKLFSMIKTGNFAFPSPYWDQISNEAKELIKGLLTIDPAKR 256
>UniRef50_UPI00006CD5AE Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 779
Score = 143 bits (346), Expect = 1e-32
Identities = 69/183 (37%), Positives = 107/183 (58%), Gaps = 3/183 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + +++ Y++ ++ Y GG++ + K E ++ Y AQ+VLALE LH ++
Sbjct: 513 IKLHYAFQNDWYLFMVMEYAEGGDMGNYLNKRNKLPEDEARIYTAQIVLALEELHKQDII 572
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI-IKSRTWT--LCGTPEYLAPELILSKGYSFPVD 117
RDLKP+NV++ G KL DFG K IK T+T CG+ YLAPE++ + +S VD
Sbjct: 573 FRDLKPDNVVLDHLGNAKLTDFGLSKEGIKENTFTKSFCGSVAYLAPEVLAKRPHSRTVD 632
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
W+ LG +YE++ PP+Y + LY+ I G K P +M+ K L+K LL +P +R
Sbjct: 633 WYLLGTFLYELLVGIPPYYDNNKEILYDNIRRGPLKIPRSMSADAKDLIKQLLNRNPKER 692
Query: 178 YGS 180
GS
Sbjct: 693 LGS 695
>UniRef50_UPI0000519F68 Cluster: PREDICTED: similar to
cGMP-dependent protein kinase 21D CG3324-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to cGMP-dependent
protein kinase 21D CG3324-PA - Apis mellifera
Length = 639
Score = 143 bits (346), Expect = 1e-32
Identities = 77/184 (41%), Positives = 113/184 (61%), Gaps = 5/184 (2%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T KD Y+YF++ GG+L T + + G ++ S+F A +V A YLH +++RDLK
Sbjct: 397 TFKDKKYLYFLMEVGLGGDLRTALYRHGQYNNWTSRFIIACIVEAFHYLHSLGIIYRDLK 456
Query: 66 PENVLVSSSGYIKLADFGFCKIIKS-RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVL 124
PEN++++S GYIKL DFG K I S +T T GT EYLAPE+I SK Y+ VD+WALG+L
Sbjct: 457 PENIVINSIGYIKLIDFGSTKKIGSYKTKTFIGTLEYLAPEIIQSKHYNRAVDYWALGIL 516
Query: 125 IYEMIAAFPPFYSSEPIKLYEKILTG---QFKTPENMTQVCKALVKNLLEVDPTKRYGSL 181
YE++ PF + +++ IL G + +P + K +K+LL+ +P R G L
Sbjct: 517 TYEILENKTPFQAINDLEICNNILRGFNDNYFSP-FIKSAGKDFIKSLLQNNPLNRLGCL 575
Query: 182 KAGV 185
+ GV
Sbjct: 576 QNGV 579
>UniRef50_Q84QE0 Cluster: Avr9/Cf-9 rapidly elicited protein 216;
n=2; core eudicotyledons|Rep: Avr9/Cf-9 rapidly elicited
protein 216 - Nicotiana tabacum (Common tobacco)
Length = 413
Score = 143 bits (346), Expect = 1e-32
Identities = 71/172 (41%), Positives = 105/172 (61%), Gaps = 7/172 (4%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YF++ Y GGEL+T I G FSE LS+ Y QL+ AL Y H + HRDLKPEN+L+
Sbjct: 82 IYFVMEYVKGGELFTKIADHGRFSEDLSRKYFQQLISALNYCHSRGIYHRDLKPENILID 141
Query: 73 SSGYIKLADFGFC----KIIK--SRTWTLCGTPEYLAPELILSKGY-SFPVDWWALGVLI 125
+G +K++DFG +I K T+CG+P Y+APE++ KGY D W+ G+++
Sbjct: 142 ENGDLKISDFGLSATTDQIQKFDGLLHTVCGSPAYVAPEILTIKGYDGAKTDIWSCGIIL 201
Query: 126 YEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
Y MIA + PFY + +Y+KI G+FK P+ M+ ++ LL+ +P R
Sbjct: 202 YVMIAGYLPFYDQNLMLMYKKIYKGEFKCPKWMSPDVIRILSRLLDTNPATR 253
>UniRef50_Q54PK9 Cluster: Putative uncharacterized protein pdkB;
n=1; Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein pdkB - Dictyostelium discoideum
AX4
Length = 908
Score = 143 bits (346), Expect = 1e-32
Identities = 70/184 (38%), Positives = 108/184 (58%), Gaps = 7/184 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L +T +D +YFIL Y G+L +KK G FS + +FYAA++++ALEYLH +
Sbjct: 332 VKLFYTFQDENNLYFILEYCPNGDLLGALKKAGCFSIDVVRFYAAEILIALEYLHGKGIA 391
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIK-------SRTWTLCGTPEYLAPELILSKGYS 113
HRDLKPEN+L+ + ++KL+DFG K + SR+ + CGT EY+ PEL+ K
Sbjct: 392 HRDLKPENILLGKNQHLKLSDFGSAKQLSIGSHHKGSRSGSFCGTAEYVCPELLTEKSAG 451
Query: 114 FPVDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVD 173
D W+ G L+Y++++ PF + + I +F P+N + C L+ LL++D
Sbjct: 452 VEADIWSYGCLLYQLVSGKLPFKGFNEYQTFLLITKREFSYPDNFDKCCMNLIDQLLDLD 511
Query: 174 PTKR 177
P KR
Sbjct: 512 PYKR 515
>UniRef50_A0E0G1 Cluster: Chromosome undetermined scaffold_71, whole
genome shotgun sequence; n=5; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_71,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 779
Score = 143 bits (346), Expect = 1e-32
Identities = 76/190 (40%), Positives = 111/190 (58%), Gaps = 11/190 (5%)
Query: 8 KDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPE 67
KD Y+Y + Y G EL+ +I+++G + +QFY AQ++ LE LH +++RD+KPE
Sbjct: 534 KDQNYIYLLTEYVKGKELFHVIREIGLLNSYETQFYIAQMINILEKLHSQHIIYRDVKPE 593
Query: 68 NVLVSSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSKGYSFPVDWWALGVL 124
N +V +GYIKL D G K++KSR T+TL GTP Y+APE++ KGYSF D W+LG+
Sbjct: 594 NFIVMENGYIKLIDMGTAKVLKSRASKTYTLVGTPHYMAPEILKGKGYSFSTDLWSLGIC 653
Query: 125 IYEMIAAFPPFYSSE---PIKLYEKILTGQFKTPENMTQV-CKALVKNLLEVDPTKRYGS 180
YE++ PF E P + E IL G+ + P+ + L+ L+ P R G
Sbjct: 654 FYELMCGEVPFAGDEEDDPFIIEEAILNGKLEYPQILKDFKAIKLMDQLMNRTPELRLG- 712
Query: 181 LKAGVFRALE 190
G F AL+
Sbjct: 713 ---GSFEALK 719
>UniRef50_A0CNT4 Cluster: Chromosome undetermined scaffold_22, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_22,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 362
Score = 143 bits (346), Expect = 1e-32
Identities = 74/184 (40%), Positives = 107/184 (58%), Gaps = 5/184 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L++ ++ +YF L Y GGELY L+ + +E ++FYA+Q++LA +YLH ++
Sbjct: 95 IKLEYAFQNETKLYFCLQYCPGGELYQLLVQKNKLTEEQAKFYASQIILAFQYLHEQDII 154
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKI-IKSR--TWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLKPENVL+ GYIKL DFGF K I+ + CGT EYLAPEL L+ + D
Sbjct: 155 YRDLKPENVLIDQEGYIKLTDFGFSKQGIQGNFGAHSKCGTAEYLAPEL-LAGNHGKAAD 213
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPE-NMTQVCKALVKNLLEVDPTK 176
WW G LIYEM+ P F+ +L+ +IL + + + K L+ LL+ DP
Sbjct: 214 WWTFGTLIYEMVIGQPAFFGETKEELFNQILHHEINYKKIGASSQFKDLLSKLLQKDPNN 273
Query: 177 RYGS 180
R S
Sbjct: 274 RISS 277
>UniRef50_Q6UB97 Cluster: Protein kinase C 1; n=7; Dikarya|Rep:
Protein kinase C 1 - Cryptococcus neoformans var. grubii
(Filobasidiella neoformans var.grubii)
Length = 1086
Score = 143 bits (346), Expect = 1e-32
Identities = 68/171 (39%), Positives = 109/171 (63%), Gaps = 4/171 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
VYF++ Y +GG+L I+K F+ ++FYA +++LAL+Y H +++RDLK +N+L++
Sbjct: 833 VYFVMEYISGGDLMLHIQKKQ-FTLRQAKFYACEVLLALQYFHSKGIIYRDLKLDNILLT 891
Query: 73 SSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
G++K+AD+G CK T T CGTPE++APE++L + Y VDWWA GVL YEM+
Sbjct: 892 LDGHVKVADYGLCKEEMWFGKTTSTFCGTPEFMAPEILLEQRYGRAVDWWAFGVLTYEML 951
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PF + ++++ IL + P M + +L++ LL DPT+R G+
Sbjct: 952 LGQSPFRGEDEDEIFDAILEDEPLYPITMPRDAVSLLQRLLTRDPTRRLGA 1002
>UniRef50_UPI00006A0113 Cluster: UPI00006A0113 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A0113 UniRef100 entry -
Xenopus tropicalis
Length = 292
Score = 142 bits (345), Expect = 2e-32
Identities = 70/167 (41%), Positives = 107/167 (64%), Gaps = 5/167 (2%)
Query: 17 LPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVSSSGY 76
+ Y AGG+LY +++ G F + + FYA +VL L++LH +++HRD+KPEN+L++S GY
Sbjct: 92 IDYCAGGDLYKQVEE-GPFPQEKAVFYAGCIVLGLQFLHKNNIIHRDIKPENILIASDGY 150
Query: 77 IKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAAFP 133
K+ DFG K ++ T T CGT Y+APE++ ++ VDWWALG++IYEMI P
Sbjct: 151 TKITDFGLAKKTETYGGITNTFCGTRYYMAPEIVKKDCHTKSVDWWALGIVIYEMIRGVP 210
Query: 134 PFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
PF + I L EKI + P ++ V +L++ LL+ DP +R G+
Sbjct: 211 PFLGQKQIVL-EKIKNEEPPYPSVLSVVAVSLIQGLLKKDPMERLGA 256
>UniRef50_Q9BMX6 Cluster: Phosphoinositide-dependent protein kinase
I; n=2; Protostomia|Rep: Phosphoinositide-dependent
protein kinase I - Aplysia californica (California sea
hare)
Length = 822
Score = 142 bits (345), Expect = 2e-32
Identities = 72/189 (38%), Positives = 108/189 (57%), Gaps = 7/189 (3%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L +T +D +Y+ L Y GEL + KL F P ++FY A++VLALEYLH +VHR
Sbjct: 435 LAYTFQDPERLYYTLTYARNGELLGYLHKLSAFDVPCTRFYTAEIVLALEYLHSLGIVHR 494
Query: 63 DLKPENVLVSSSGYIKLADFGFCKIIKS-------RTWTLCGTPEYLAPELILSKGYSFP 115
DLKPEN+L+S +IK+ DFG KI+ S R + GT EY++PE++ ++ +F
Sbjct: 495 DLKPENILLSEDMHIKITDFGTSKILSSDSKPEVKRKNSFVGTAEYVSPEVLNNQPANFG 554
Query: 116 VDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPT 175
D W LG +IY+ ++ PF + ++KI+ ++ PE K LV+ LL ++P
Sbjct: 555 SDLWGLGCIIYQCLSGSLPFRCGNEYQTFQKIVKAEYDFPEGFHPHAKDLVQKLLVIEPA 614
Query: 176 KRYGSLKAG 184
R G G
Sbjct: 615 DRLGMADMG 623
>UniRef50_A0BQE1 Cluster: Chromosome undetermined scaffold_120,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_120,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 678
Score = 142 bits (345), Expect = 2e-32
Identities = 68/172 (39%), Positives = 109/172 (63%), Gaps = 4/172 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
++ IL Y GG+L L+ K+ F E L + Y +++LALE LH ++ RDLKP+N+L+
Sbjct: 438 LFMILDYCPGGDLGMLLCKIKRFPEELVKLYTCEIILALEDLHKRDIIFRDLKPDNILLD 497
Query: 73 SSGYIKLADFGFCK--IIKSR--TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEM 128
+ G++ L DFG K I +S + CG+ YLAPE++ +G+ VDW+ LGV++YE+
Sbjct: 498 ADGHVLLTDFGLSKEGIPQSSKGAQSFCGSVAYLAPEMLKRQGHGKAVDWYLLGVVMYEL 557
Query: 129 IAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
+ PP+Y ++ L+ I K P++++ C+ L+K+LLE +PTKR GS
Sbjct: 558 LVGLPPYYDNDRDTLFYNIENASLKIPQHISIECRTLLKSLLERNPTKRLGS 609
>UniRef50_A0EIN6 Cluster: Chromosome undetermined scaffold_99, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_99,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 603
Score = 142 bits (344), Expect = 2e-32
Identities = 68/175 (38%), Positives = 112/175 (64%), Gaps = 5/175 (2%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
Y+ F++ Y GGEL+ ++K+G SE +++ Y QL LA+ YLH +V++RDLKPEN+L+
Sbjct: 254 YLVFVMDYCHGGELFFHLRKMGTLSEEVAKQYFGQLCLAIHYLHEQNVIYRDLKPENILL 313
Query: 72 SSSGYIKLADFGFCKIIKSR---TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEM 128
GYIKL+DFG K SR T++ CG+PEY++PE++ +G++ +D ++LG ++YE
Sbjct: 314 DIDGYIKLSDFGLSKPNISRDKQTYSFCGSPEYMSPEMVSKRGHNQLLDCYSLGAVLYEF 373
Query: 129 IAAFPPFYSSEPIKLYEKILTGQFKTPEN--MTQVCKALVKNLLEVDPTKRYGSL 181
I +PP+Y + + I + + PE+ ++ K L+ NLL D +R G +
Sbjct: 374 IYGYPPYYDQQLQNILNSIQYDKLEFPEHIKISDQLKNLLLNLLTKDQNERLGRM 428
>UniRef50_A0D680 Cluster: Chromosome undetermined scaffold_39, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_39,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 750
Score = 142 bits (344), Expect = 2e-32
Identities = 66/182 (36%), Positives = 116/182 (63%), Gaps = 5/182 (2%)
Query: 5 FTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDL 64
+ + + F+L Y +GGEL+ L++K+ SE + FY +++ L ++ LH+ ++++RD+
Sbjct: 427 YAFESRRFFVFVLEYCSGGELFFLLRKIKRMSEKDAFFYFSEICLGMKTLHYNNIIYRDI 486
Query: 65 KPENVLVSSSGYIKLADFGFCK--IIKS-RTWTLCGTPEYLAPELILSKGYSFPVDWWAL 121
KPEN+L+ G+I++ADFG K II++ ++ CG+ EY+APE++L G++F +D + L
Sbjct: 487 KPENILIDMDGHIRIADFGLSKPNIIETENAYSFCGSSEYMAPEMLLKCGHTFQLDLYCL 546
Query: 122 GVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPE--NMTQVCKALVKNLLEVDPTKRYG 179
G L+YE+I PPFYS ++Y++IL + P ++ K L+ NLL +P R
Sbjct: 547 GALLYELITGLPPFYSRNLEEIYQRILNQKLNFPPQLQLSSSIKHLLTNLLAKNPNDRID 606
Query: 180 SL 181
S+
Sbjct: 607 SI 608
>UniRef50_Q04759 Cluster: Protein kinase C theta type; n=20;
Euteleostomi|Rep: Protein kinase C theta type - Homo
sapiens (Human)
Length = 706
Score = 142 bits (344), Expect = 2e-32
Identities = 69/182 (37%), Positives = 109/182 (59%), Gaps = 5/182 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
M F K+N++ F++ Y GG+L I+ F + FYAA+++L L++LH +V
Sbjct: 444 MFCTFQTKENLF--FVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIV 501
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK---IIKSRTWTLCGTPEYLAPELILSKGYSFPVD 117
+RDLK +N+L+ G+IK+ADFG CK + ++T T CGTP+Y+APE++L + Y+ VD
Sbjct: 502 YRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVD 561
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW+ GVL+YEM+ PF+ + +L+ I P + + K L+ L +P KR
Sbjct: 562 WWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKR 621
Query: 178 YG 179
G
Sbjct: 622 LG 623
>UniRef50_P34885 Cluster: Protein kinase C-like 1B; n=4;
Bilateria|Rep: Protein kinase C-like 1B - Caenorhabditis
elegans
Length = 707
Score = 142 bits (344), Expect = 2e-32
Identities = 69/170 (40%), Positives = 105/170 (61%), Gaps = 3/170 (1%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
++F++ Y GG+L I++ F E ++FYAA++ AL++LH V++RDLK +N+L+
Sbjct: 452 LFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRNDVIYRDLKLDNILLD 511
Query: 73 SSGYIKLADFGFCK--IIKSR-TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
+ G+ +LADFG CK I K T T CGTP+Y+APE++ Y VDWWALGVL+YEM+
Sbjct: 512 AEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMM 571
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
A PPF + L+E IL P +++ ++K + + KR G
Sbjct: 572 AGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFMTKNAGKRLG 621
>UniRef50_UPI00015B5903 Cluster: PREDICTED: similar to Melk protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to Melk
protein - Nasonia vitripennis
Length = 1491
Score = 142 bits (343), Expect = 3e-32
Identities = 73/171 (42%), Positives = 103/171 (60%), Gaps = 5/171 (2%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
+ + +L Y +GGEL+ I + SE S+ + Q+V A+ YLH VHRDLKPENVL+
Sbjct: 990 HYFMVLEYCSGGELFDHIVEKSKLSESESRRFFRQIVSAVAYLHSLGYVHRDLKPENVLL 1049
Query: 72 SSSGYIKLADFGFCKI----IKSRTWTLCGTPEYLAPELILSKGY-SFPVDWWALGVLIY 126
+KL DFG C I+S +T CG+P Y APELIL Y +D W+LGVL+Y
Sbjct: 1050 DKDQNLKLIDFGLCAKPKGGIQSPLYTSCGSPAYAAPELILGNKYLGSEIDIWSLGVLLY 1109
Query: 127 EMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
++ F PF + LY+KIL GQ+ P M+Q + L++ +L++DP KR
Sbjct: 1110 ALLCGFLPFDDNNIENLYKKILNGQYDEPSWMSQSSRRLIRAMLQIDPRKR 1160
>UniRef50_UPI0001509D2B Cluster: Protein kinase C terminal domain
containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Protein kinase C terminal domain containing
protein - Tetrahymena thermophila SB210
Length = 408
Score = 142 bits (343), Expect = 3e-32
Identities = 72/173 (41%), Positives = 109/173 (63%), Gaps = 6/173 (3%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+Y ++ + GGELY +KK F E ++FY AQ++LA+E LH ++++RDLK EN+L+
Sbjct: 138 LYLMMDFMVGGELYYHLKKAKKFDEERTKFYIAQVILAIECLHQNNIMYRDLKLENILLG 197
Query: 73 SSGYIKLADFGFCKI-IKSR--TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
GYIKL DFG K IK + T TLCGT EY+APE I+++G++ D+W +GVL YEM+
Sbjct: 198 QDGYIKLTDFGLSKEGIKDKDLTNTLCGTAEYMAPEQIMNEGHNKMADFWQIGVLTYEML 257
Query: 130 AAFPPFYSS-EPIK--LYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYG 179
PF++ P K ++ I+ G++ P+ K ++ LL+ D KR G
Sbjct: 258 YGTTPFFNEFRPNKDEIFNDIIQGKYTFPQYFKDDAKNFIRGLLQKDVKKRLG 310
>UniRef50_O17874 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 1012
Score = 142 bits (343), Expect = 3e-32
Identities = 68/182 (37%), Positives = 110/182 (60%), Gaps = 4/182 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
++L+ + N +V+F + Y GG+L I F E FYAA +VL L++LH +++
Sbjct: 748 VNLNGCFQTNEHVFFCMEYSMGGDLMRHIHD-DVFDEVRGCFYAACVVLGLDFLHKHNII 806
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKS---RTWTLCGTPEYLAPELILSKGYSFPVD 117
+RD+K +N+L+ GY+K+ADFG CK +T T CGTPE+LAPE++ Y+ +D
Sbjct: 807 YRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTFCGTPEFLAPEVLSDSSYTRAID 866
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
WW LGVLI+EM+ PPF + ++++ I++ + P ++ A+++ LL P KR
Sbjct: 867 WWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAIMRRLLRKVPEKR 926
Query: 178 YG 179
G
Sbjct: 927 LG 928
>UniRef50_A5DM82 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 1047
Score = 142 bits (343), Expect = 3e-32
Identities = 68/183 (37%), Positives = 111/183 (60%), Gaps = 4/183 (2%)
Query: 13 VYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVS 72
+YF++ Y +GG+L I+K FS ++FYA +++LAL+Y H +V+RD+K +N+L++
Sbjct: 796 IYFVMEYISGGDLMWHIQK-SRFSAKRAKFYACEVLLALKYFHENGIVYRDIKLDNILLT 854
Query: 73 SSGYIKLADFGFCKIIK---SRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
+ G+IK+ D+G CK + T T CGTPE++APE+I K Y VDWWALGVL+++M+
Sbjct: 855 TKGHIKIGDYGLCKENMWQGNTTATFCGTPEFMAPEIISGKQYDRAVDWWALGVLLFQML 914
Query: 130 AAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSLKAGVFRAL 189
PF + +++ I + P NM + +++ LL DP R GS +
Sbjct: 915 LCQSPFKGDDEDEIFNAIEHDDVRYPINMPRQTVLVLQALLTKDPLSRLGSGPRDAEEIM 974
Query: 190 EYP 192
++P
Sbjct: 975 DHP 977
>UniRef50_UPI000065EC1B Cluster: Homolog of Fugu rubripes "Protein
kinase C, alpha type.; n=1; Takifugu rubripes|Rep:
Homolog of Fugu rubripes "Protein kinase C, alpha type.
- Takifugu rubripes
Length = 982
Score = 141 bits (342), Expect = 4e-32
Identities = 65/172 (37%), Positives = 108/172 (62%), Gaps = 4/172 (2%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
+V F++ Y GG+L T I F+E ++FY++ ++L LE+LH +++RDLK +N+L+
Sbjct: 735 HVCFVMAYSPGGDLMTHIHT-SIFTEKQARFYSSCVLLGLEFLHQNKIIYRDLKLDNLLM 793
Query: 72 SSSGYIKLADFGFCKIIKS---RTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEM 128
+ G++++ADFG CK RT T CGTPE+LAPE++ Y+ VDWW LGVLIYEM
Sbjct: 794 DADGFVRIADFGLCKEGMGHGDRTSTFCGTPEFLAPEVLTESNYTRSVDWWGLGVLIYEM 853
Query: 129 IAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
+ PF + ++++ I+ + P ++ +L++ LL+ +P R G+
Sbjct: 854 LVGESPFPGDDEEEVFDSIVNDDVRCPRFLSPQSASLIQQLLQKNPETRLGA 905
>UniRef50_A0CP93 Cluster: Chromosome undetermined scaffold_23, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_23,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 618
Score = 141 bits (342), Expect = 4e-32
Identities = 65/185 (35%), Positives = 112/185 (60%), Gaps = 3/185 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+ L + + ++ ++ + GG+L L+ SE +++ Y A+++LA+E LH ++
Sbjct: 371 VKLHYAFQTQHKLFLVMDFCPGGDLTKLLDLKSRLSEQVAKMYTAEIILAIEALHQNKIM 430
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCK--IIKSRTWTLCGTPEYLAPELILSKGYSFPVDW 118
+RDLKP+N+++ + G+ L DFG K I T + CGTP Y+APE++ K Y+ VDW
Sbjct: 431 YRDLKPQNIIIDNKGHCMLTDFGLAKTDIENENTKSFCGTPAYMAPEVVNRKFYNRSVDW 490
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPE-NMTQVCKALVKNLLEVDPTKR 177
+ LG + +EM+ PP+YS +L+E I Q K P+ N+++ + ++ LLE +PTKR
Sbjct: 491 YQLGTITHEMLFGMPPYYSHNREELFENIKNKQLKFPQNNLSKEALSFIQQLLERNPTKR 550
Query: 178 YGSLK 182
G+ K
Sbjct: 551 LGAKK 555
>UniRef50_UPI000069DCCB Cluster: UPI000069DCCB related cluster;
n=10; Xenopus tropicalis|Rep: UPI000069DCCB UniRef100
entry - Xenopus tropicalis
Length = 338
Score = 140 bits (340), Expect = 7e-32
Identities = 76/191 (39%), Positives = 113/191 (59%), Gaps = 7/191 (3%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL T + +++F++ Y GG+L L++ G F E + FY A +VL LE LH ++V
Sbjct: 73 VSLYATFQSENHLFFVMEYLPGGDLCHLLEHQGAFEESKAMFYTACIVLGLEELHRNNIV 132
Query: 61 HR--DLKPENVLVSSSGYIKLADFGFCKI-----IKSRTWTLCGTPEYLAPELILSKGYS 113
HR DLK EN++V GY+K+ DFG K R+ TLCGT Y+APE+I YS
Sbjct: 133 HRFRDLKLENLMVDVHGYLKIVDFGLSKDGNGFRYGDRSKTLCGTNCYMAPEIIDEMAYS 192
Query: 114 FPVDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVD 173
VDWWALGV++Y MI PF + + ++L+E I + E +++ + L+ LLE +
Sbjct: 193 RAVDWWALGVVLYVMIMFQFPFDAEDDMELFESIRNDKPALTEELSEEAQCLILRLLEKN 252
Query: 174 PTKRYGSLKAG 184
P +R G +AG
Sbjct: 253 PCRRLGYSEAG 263
>UniRef50_Q229R8 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1237
Score = 140 bits (340), Expect = 7e-32
Identities = 66/160 (41%), Positives = 102/160 (63%), Gaps = 3/160 (1%)
Query: 21 AGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVSSSGYIKLA 80
A GEL+ +++ E + A QL+LAL+YLH ++HRD+KP+N+L+S++G +KL
Sbjct: 65 AQGELFEILEDDRSLPESEVRKIAQQLILALDYLHSNRIIHRDMKPQNILISANGVVKLC 124
Query: 81 DFGFCKIIKSRTWTLC---GTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAAFPPFYS 137
DFGF + + S T L GTP Y+APEL+ + Y+ VD W+LGV++YE+ PPFY+
Sbjct: 125 DFGFARALSSNTQVLTSIKGTPLYMAPELVKEQPYNHTVDLWSLGVILYELFVGQPPFYT 184
Query: 138 SEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
+ KL + I+ K P+NM+Q K + LL +P++R
Sbjct: 185 NSIYKLIDLIIKDPVKYPDNMSQEFKDFLMGLLNKNPSER 224
>UniRef50_A2F0I9 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 405
Score = 140 bits (340), Expect = 7e-32
Identities = 68/182 (37%), Positives = 105/182 (57%), Gaps = 5/182 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+++ + ++ +Y + Y GGEL+ +++ + + Y A++ LALEY+H +V
Sbjct: 149 VNIKYAFQNETKLYIGMEYVPGGELFHMMQIVENLPMKAIRIYVAEVGLALEYIHSLGIV 208
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKII-----KSRTWTLCGTPEYLAPELILSKGYSFP 115
+RDLKPEN+L+++ G+IKL DFG K++ + T T CGT EYL PE+I + Y
Sbjct: 209 YRDLKPENILITAEGHIKLTDFGLAKVLPEDEGEDTTKTFCGTNEYLPPEMIKREYYGAM 268
Query: 116 VDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPT 175
+DWWALG+L YE+I PF K+YEKI + P+N + LL+ DP
Sbjct: 269 IDWWALGILTYELIYGDTPFVHKSKHKMYEKICNEEPHFPDNEDPNVVDFITKLLKKDPK 328
Query: 176 KR 177
KR
Sbjct: 329 KR 330
>UniRef50_A2EE93 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 435
Score = 140 bits (340), Expect = 7e-32
Identities = 70/182 (38%), Positives = 102/182 (56%), Gaps = 5/182 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+++ F + + Y L Y GG L+ ++ +FY A++ LAL+YLH ++
Sbjct: 181 VTMYFAFQTDKKFYIGLEYVPGGALFRFLQIGRAMKISEVRFYVAEVALALDYLHSKGIL 240
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIKSR-----TWTLCGTPEYLAPELILSKGYSFP 115
+RDLK ENVL+ G++KL DFG K + + T T CGT EYL+PE+I K Y F
Sbjct: 241 YRDLKLENVLLCQDGHVKLTDFGLSKFVVEKGNYQQTSTFCGTNEYLSPEMISDKPYGFE 300
Query: 116 VDWWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPT 175
+DWW LGV YE + PFY KLY ILT + + P++ V K ++ LL +P+
Sbjct: 301 IDWWTLGVFTYEFLFTETPFYDKNLKKLYNNILTKEPRFPKDTPSVVKNFIRRLLNKEPS 360
Query: 176 KR 177
KR
Sbjct: 361 KR 362
>UniRef50_A2DA20 Cluster: AGC family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 442
Score = 140 bits (340), Expect = 7e-32
Identities = 69/179 (38%), Positives = 97/179 (54%), Gaps = 2/179 (1%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVV 60
+SL F + Y + Y GGEL+ + K+G +FYAA++ LAL +LH ++
Sbjct: 171 VSLSFAFQSMSKFYLGMQYIPGGELFRYLSKVGKLQMSEVRFYAAEIGLALSHLHSNGII 230
Query: 61 HRDLKPENVLVSSSGYIKLADFGFCKIIK--SRTWTLCGTPEYLAPELILSKGYSFPVDW 118
+RDLKPEN+L+ G+IKL DFG K + S T T CGT EYLAPE++ + Y +DW
Sbjct: 231 YRDLKPENILLDEEGHIKLTDFGLAKDMSFDSATSTFCGTVEYLAPEIVRREPYGMAIDW 290
Query: 119 WALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
W+ G L+YE I PFY K++ +I Q P + + LL DP R
Sbjct: 291 WSYGCLVYEFIFGHTPFYDENRAKIFMRIPADQPYYPSDFDPNVSDFINQLLSKDPETR 349
>UniRef50_P38991 Cluster: Spindle assembly checkpoint kinase; n=5;
Saccharomycetales|Rep: Spindle assembly checkpoint
kinase - Saccharomyces cerevisiae (Baker's yeast)
Length = 367
Score = 140 bits (340), Expect = 7e-32
Identities = 66/171 (38%), Positives = 104/171 (60%), Gaps = 2/171 (1%)
Query: 9 DNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPEN 68
D VY ++ Y GE+Y L++ G F++ L+ Y Q+ AL+Y+H +++HRD+KPEN
Sbjct: 173 DEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPEN 232
Query: 69 VLVSSSGYIKLADFGFCKII--KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIY 126
+L+ + IKL DFG+ I ++R T+CGT +YL+PE++ S+ Y +D WALGVL +
Sbjct: 233 ILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAF 292
Query: 127 EMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
E++ PPF Y++I K P N++Q + L+ LL+ DP R
Sbjct: 293 ELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDR 343
>UniRef50_Q9C098 Cluster: Serine/threonine-protein kinase DCLK3;
n=13; Eumetazoa|Rep: Serine/threonine-protein kinase
DCLK3 - Homo sapiens (Human)
Length = 648
Score = 140 bits (340), Expect = 7e-32
Identities = 78/179 (43%), Positives = 105/179 (58%), Gaps = 10/179 (5%)
Query: 10 NMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENV 69
+M +Y IL Y GG+L+ I + F EP + L AL ++H S+VHRDLKPEN+
Sbjct: 424 DMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENL 483
Query: 70 LVS----SSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLI 125
LV S +KLADFG K + +T+CGTP Y+APE++ KGY VD WA GV++
Sbjct: 484 LVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVIL 543
Query: 126 YEMIAAFPPFYSSE--PIKLYEKILTGQFK-TP---ENMTQVCKALVKNLLEVDPTKRY 178
Y ++ FPPF S E +L+ I G F+ P +N++ K LV LL VDP KRY
Sbjct: 544 YILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRY 602
>UniRef50_UPI0000E46D98 Cluster: PREDICTED: similar to doublecortin
and CaM kinase-like 3; n=6; Deuterostomia|Rep:
PREDICTED: similar to doublecortin and CaM kinase-like 3
- Strongylocentrotus purpuratus
Length = 991
Score = 140 bits (339), Expect = 9e-32
Identities = 76/177 (42%), Positives = 107/177 (60%), Gaps = 10/177 (5%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLV 71
++Y ++ Y GG+L+ I + F+E + L AL+YLH +VVHRDLKPEN+LV
Sbjct: 765 HIYLVMEYVTGGDLFDAITESVKFTERDAALMVTDLAKALKYLHDLNVVHRDLKPENLLV 824
Query: 72 --SSSGYI--KLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYE 127
S SG I KLADFG +K +T+CGTP Y+APE++ KGY VD WA+GV+ Y
Sbjct: 825 NKSESGEITLKLADFGLAMEVKEPIYTVCGTPTYVAPEILGEKGYGLEVDMWAIGVITYI 884
Query: 128 MIAAFPPFYS--SEPIKLYEKILTGQFK--TP--ENMTQVCKALVKNLLEVDPTKRY 178
++ FPPF S + +L+E I G F P +N++ K L+ +LL V+ KRY
Sbjct: 885 LLCGFPPFRSPDRDQEELFELIQEGAFSFVAPYWDNISSAAKDLINHLLVVNKEKRY 941
>UniRef50_Q4Q7M5 Cluster: Rac serine-threonine kinase, putative;
n=3; Leishmania|Rep: Rac serine-threonine kinase,
putative - Leishmania major
Length = 510
Score = 140 bits (339), Expect = 9e-32
Identities = 73/185 (39%), Positives = 112/185 (60%), Gaps = 4/185 (2%)
Query: 3 LDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHR 62
L ++ ++ +Y IL AGGEL+T I++ E + +FYAA++ LAL YLH ++++R
Sbjct: 168 LHYSFQEQGNLYMILDLLAGGELFTYIEQHAPLDEEVVKFYAAEVALALGYLHSRNIIYR 227
Query: 63 DLKPENVLVSSSGYIKLADFGFCK--IIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWA 120
DLKPENV+ G+ L DFG K + + T CGT EYLAPEL+ + VDWW+
Sbjct: 228 DLKPENVVFDRDGHACLTDFGLAKANVHEPNAVTYCGTNEYLAPELLKGVPHGKAVDWWS 287
Query: 121 LGVLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPEN--MTQVCKALVKNLLEVDPTKRY 178
LG+++ EM+ PFY P+++ KILT P + +T+ K L++ LL +P +R
Sbjct: 288 LGLMMCEMLFNDLPFYDENPMQMQMKILTEDVAFPPHIQITEETKDLIRCLLNKNPERRL 347
Query: 179 GSLKA 183
+L+A
Sbjct: 348 QTLEA 352
>UniRef50_Q22RR1 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila SB210
Length = 1219
Score = 140 bits (339), Expect = 9e-32
Identities = 71/189 (37%), Positives = 119/189 (62%), Gaps = 14/189 (7%)
Query: 9 DNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPEN 68
DN ++YF+ + G + +T+++++G F++ +QFY A ++L L+YL++ +V+RDLKPEN
Sbjct: 952 DNYHIYFMNEFINGMDFFTVMREVGLFNKQQAQFYTAFIILTLQYLNNQGIVYRDLKPEN 1011
Query: 69 VLVSSSGYIKLADFGFCKII------KSRTWTLCGTPEYLAPELILSKGYSFPVDWWALG 122
+L+ G+ KL D G K + +RT++L GTP Y+APE+I KGY F VD ++LG
Sbjct: 1012 ILIDHEGWPKLVDMGTAKYLYDKNQQLTRTYSLVGTPHYMAPEVIQQKGYGFAVDIYSLG 1071
Query: 123 VLIYEMIAAFPPFYS--SEPIKLYEKILTGQFKTPENMTQVC--KALVKNLLEVDPTKR- 177
V++YE++ + P+ +PI++Y+ IL G+ P +M K L+ L+ P R
Sbjct: 1072 VILYELLVGYLPYGEDVDDPIEVYQLILEGRLGFPNHMKNRLSDKKLISQLMAKSPEVRL 1131
Query: 178 ---YGSLKA 183
YG+LK+
Sbjct: 1132 GGSYGALKS 1140
>UniRef50_A2G1Q9 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 326
Score = 140 bits (339), Expect = 9e-32
Identities = 69/166 (41%), Positives = 97/166 (58%), Gaps = 2/166 (1%)
Query: 14 YFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLKPENVLVSS 73
Y + Y GG+L L++++G S YA ++ LALE++H +V+RDLKPEN++++S
Sbjct: 78 YIGMEYVPGGDLIGLMRRVGKLSMNDVIIYAGEVALALEFIHSKEIVYRDLKPENLVINS 137
Query: 74 SGYIKLADFGFCKIIKSR--TWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMIAA 131
G++KLADFG K I T T CGT EY+APE++ K Y + VDWWA G+L+YEMI
Sbjct: 138 DGHLKLADFGLSKDISESKLTNTFCGTSEYMAPEMLFKKFYDYSVDWWAFGILVYEMIFD 197
Query: 132 FPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKR 177
PF+S + KI PE + + LE DP KR
Sbjct: 198 ATPFHSELKDSTFSKIKYADPTYPEGTDPNIISFINGFLEKDPHKR 243
>UniRef50_Q6BHW6 Cluster: Debaryomyces hansenii chromosome G of
strain CBS767 of Debaryomyces hansenii; n=3;
Saccharomycetaceae|Rep: Debaryomyces hansenii chromosome
G of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 449
Score = 140 bits (339), Expect = 9e-32
Identities = 69/183 (37%), Positives = 117/183 (63%), Gaps = 5/183 (2%)
Query: 1 MSLDFTCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHH-CSV 59
+SL + +DN VY IL Y +GGEL+ + + SE + +Y AQ++LAL YLH+ V
Sbjct: 168 VSLYYAFQDNDKVYLILEYLSGGELFHHLAQEKFMSEKNASYYIAQIILALRYLHNKLGV 227
Query: 60 VHRDLKPENVLVSSSGYIKLADFGFCKIIKS--RTWTLCGTPEYLAPELILSKGYSFPVD 117
++RDLKPEN +++S G + L DFG K+ + + ++ GT +Y+APE++ S+ Y++ VD
Sbjct: 228 IYRDLKPENCMLNSYGNLVLTDFGLSKVSTTDEKKHSMTGTVQYMAPEILKSEPYTYSVD 287
Query: 118 WWALGVLIYEMIAAFPPFYSSEPIKLYEKILTGQ--FKTPENMTQVCKALVKNLLEVDPT 175
WW+LG + Y+++ PPF + K+ EK+++ + K P ++ K L++ LL+ +P
Sbjct: 288 WWSLGCVAYDLLTGSPPFNGNNNKKIIEKVISSKKTLKFPFYLSLDAKDLLRKLLQPNPY 347
Query: 176 KRY 178
KR+
Sbjct: 348 KRF 350
>UniRef50_P83099 Cluster: Putative protein kinase C delta type
homolog; n=3; Endopterygota|Rep: Putative protein kinase
C delta type homolog - Drosophila melanogaster (Fruit
fly)
Length = 671
Score = 140 bits (339), Expect = 9e-32
Identities = 66/178 (37%), Positives = 109/178 (61%), Gaps = 3/178 (1%)
Query: 6 TCKDNMYVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLHHCSVVHRDLK 65
T + +++F++ Y GG+L I++ G FSE ++FY A+++ L++LH +++RDLK
Sbjct: 410 TFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLK 469
Query: 66 PENVLVSSSGYIKLADFGFCKI---IKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALG 122
+NVL+ G++++ADFG CK+ + + CGTP+Y+APE+I + Y+ VDWW+ G
Sbjct: 470 LDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFG 529
Query: 123 VLIYEMIAAFPPFYSSEPIKLYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGS 180
VL+YEM+ PF + +L+ I P ++ ++K LLE D TKR GS
Sbjct: 530 VLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGS 587
>UniRef50_A0BYR7 Cluster: Chromosome undetermined scaffold_137,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_137,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 681
Score = 140 bits (338), Expect = 1e-31
Identities = 71/181 (39%), Positives = 109/181 (60%), Gaps = 10/181 (5%)
Query: 12 YVYFILPYEAGGELYTLIKKLGGFSEPLSQFYAAQLVLALEYLH--HCSVVHRDLKPENV 69
Y+Y IL GG+L+ + ++G F E + + + + A+EYLH + ++HRD+KPEN+
Sbjct: 106 YIYLILECATGGQLWQKLNRVGRFDEKTVKQFMQEAMSAIEYLHTRNPPIIHRDIKPENI 165
Query: 70 LVSSSGYIKLADFGFCKIIKSRTWTLCGTPEYLAPELILSKGYSFPVDWWALGVLIYEMI 129
L+ ++G+IK+ADFG+ I + T CGT +YLAPE+IL G+ +D W+LGVLIYE++
Sbjct: 166 LLDANGHIKIADFGWSNINNHQRTTYCGTLDYLAPEMILECGHDEKIDNWSLGVLIYELL 225
Query: 130 AAFPPFYSSEPIK--------LYEKILTGQFKTPENMTQVCKALVKNLLEVDPTKRYGSL 181
PF S IK L + IL + P + + K+LV+ LL+ DP KR+
Sbjct: 226 TGKAPFAPSSQIKDQKESQKILEDNILKVKINFPNDFPSLAKSLVQGLLQRDPQKRFNIQ 285
Query: 182 K 182
K
Sbjct: 286 K 286
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.323 0.139 0.427
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 641,633,193
Number of Sequences: 1657284
Number of extensions: 27225217
Number of successful extensions: 90267
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 9039
Number of HSP's successfully gapped in prelim test: 3014
Number of HSP's that attempted gapping in prelim test: 67583
Number of HSP's gapped (non-prelim): 15869
length of query: 559
length of database: 575,637,011
effective HSP length: 105
effective length of query: 454
effective length of database: 401,622,191
effective search space: 182336474714
effective search space used: 182336474714
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 75 (34.3 bits)
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