BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000982-TA|BGIBMGA000982-PA|IPR002290|Serine/threonine protein kinase, IPR000961|Protein kinase, C-terminal, IPR008271|Serine/threonine protein kinase, active site, IPR000719|Protein kinase, IPR011009|Protein kinase-like (330 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_P17612 Cluster: cAMP-dependent protein kinase, alpha-ca... 363 3e-99 UniRef50_P22612 Cluster: cAMP-dependent protein kinase, gamma-ca... 350 3e-95 UniRef50_Q17JG1 Cluster: Camp-dependent protein kinase catalytic... 345 7e-94 UniRef50_Q9VA47 Cluster: CG12069-PA; n=3; Sophophora|Rep: CG1206... 318 1e-85 UniRef50_O13367 Cluster: CAMP-dependent protein kinase catalytic... 309 8e-83 UniRef50_P51817 Cluster: Serine/threonine-protein kinase PRKX; n... 303 4e-81 UniRef50_P34099 Cluster: cAMP-dependent protein kinase catalytic... 300 3e-80 UniRef50_Q4E4S9 Cluster: Protein kinase A catalytic subunit isof... 300 4e-80 UniRef50_Q33DX4 Cluster: Putative cyclic AMP-dependent protein k... 299 5e-80 UniRef50_UPI000155CDCE Cluster: PREDICTED: similar to protein ki... 296 4e-79 UniRef50_Q8J0I6 Cluster: CAMP-dependent protein kinase A catalyt... 294 2e-78 UniRef50_Q2U6J7 Cluster: CAMP-dependent protein kinase catalytic... 285 1e-75 UniRef50_Q8NIL1 Cluster: CAMP-dependent protein kinase catalytic... 284 3e-75 UniRef50_Q20541 Cluster: Cyclic AMP-dependent protein kinase, ca... 279 9e-74 UniRef50_A0BEY5 Cluster: Chromosome undetermined scaffold_103, w... 276 7e-73 UniRef50_Q9BMY6 Cluster: CAMP-dependent protein kinase catalytic... 274 2e-72 UniRef50_P05986 Cluster: cAMP-dependent protein kinase type 3; n... 272 8e-72 UniRef50_P12688 Cluster: Serine/threonine-protein kinase YPK1; n... 271 2e-71 UniRef50_A6QTK8 Cluster: Serine/threonine-protein kinase PRKX; n... 270 3e-71 UniRef50_Q17941 Cluster: Serine/threonine-protein kinase akt-1; ... 270 3e-71 UniRef50_Q9P7J8 Cluster: Serine/threonine-protein kinase gad8; n... 269 8e-71 UniRef50_P28178 Cluster: Protein kinase 2; n=2; Dictyostelium di... 268 1e-70 UniRef50_P40376 Cluster: cAMP-dependent protein kinase catalytic... 268 1e-70 UniRef50_Q2PJ68 Cluster: Putative uncharacterized protein sgk-1;... 266 5e-70 UniRef50_Q6CW38 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 266 7e-70 UniRef50_P31751 Cluster: RAC-beta serine/threonine-protein kinas... 266 7e-70 UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta i... 265 1e-69 UniRef50_UPI000049878B Cluster: protein kinase; n=3; Entamoeba h... 262 1e-68 UniRef50_Q6CD34 Cluster: Yarrowia lipolytica chromosome C of str... 262 1e-68 UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome s... 261 2e-68 UniRef50_Q24HP6 Cluster: Protein kinase domain containing protei... 261 2e-68 UniRef50_O44020 Cluster: PKA protein; n=13; Eukaryota|Rep: PKA p... 260 3e-68 UniRef50_P11792 Cluster: Serine/threonine-protein kinase SCH9; n... 260 4e-68 UniRef50_P54644 Cluster: RAC family serine/threonine-protein kin... 260 4e-68 UniRef50_A0CMB4 Cluster: Chromosome undetermined scaffold_21, wh... 260 5e-68 UniRef50_Q5K7C2 Cluster: Protein kinase Sch9, putative; n=4; Aga... 258 1e-67 UniRef50_Q22DD1 Cluster: Protein kinase domain containing protei... 258 2e-67 UniRef50_A1CR23 Cluster: CAMP-dependent protein kinase, putative... 257 3e-67 UniRef50_UPI000049A5C0 Cluster: protein kinase; n=1; Entamoeba h... 257 3e-67 UniRef50_Q8INB9 Cluster: RAC serine/threonine-protein kinase; n=... 256 8e-67 UniRef50_Q6PLK2 Cluster: Protein kinase B-like protein; n=4; Pla... 255 1e-66 UniRef50_A5DTG0 Cluster: Serine/threonine-protein kinase YPK1; n... 254 2e-66 UniRef50_A7AWS2 Cluster: cAMP-dependent protein kinase; n=1; Bab... 253 4e-66 UniRef50_Q86ZN6 Cluster: CAMP-dependent protein kinase catalytic... 253 4e-66 UniRef50_Q2UNA7 Cluster: Ribosomal protein S6 kinase and related... 253 4e-66 UniRef50_Q4UE84 Cluster: CAMP-dependent protein kinase catalytic... 253 5e-66 UniRef50_Q9HGS0 Cluster: CAMP-dependent protein kinase catalytic... 253 5e-66 UniRef50_Q6C936 Cluster: Yarrowia lipolytica chromosome D of str... 253 5e-66 UniRef50_Q39030 Cluster: Serine/threonine-protein kinase AtPK19;... 252 9e-66 UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1; Chl... 250 3e-65 UniRef50_A0CDF0 Cluster: Chromosome undetermined scaffold_17, wh... 249 9e-65 UniRef50_Q4XNV1 Cluster: Rac-beta serine/threonine protein kinas... 248 1e-64 UniRef50_Q54IF2 Cluster: Putative uncharacterized protein; n=1; ... 247 4e-64 UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate pro... 246 5e-64 UniRef50_Q231C9 Cluster: Protein kinase C terminal domain contai... 246 6e-64 UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to cGMP-depen... 246 8e-64 UniRef50_Q39908 Cluster: CAMP-dependent protein kinase; n=1; Gon... 246 8e-64 UniRef50_UPI000150A8F4 Cluster: Protein kinase domain containing... 245 1e-63 UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23; ... 245 1e-63 UniRef50_UPI00006CFFA7 Cluster: Protein kinase domain containing... 245 1e-63 UniRef50_Q240P0 Cluster: Protein kinase domain containing protei... 244 2e-63 UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=... 244 2e-63 UniRef50_Q2U061 Cluster: Ribosomal protein S6 kinase and related... 244 2e-63 UniRef50_A5DV85 Cluster: Serine/threonine-protein kinase SCH9; n... 244 3e-63 UniRef50_UPI00006CB772 Cluster: Protein kinase domain containing... 243 4e-63 UniRef50_Q9NAH6 Cluster: Putative uncharacterized protein rsks-1... 243 4e-63 UniRef50_A0E058 Cluster: Chromosome undetermined scaffold_71, wh... 243 4e-63 UniRef50_A5K8X1 Cluster: Rac-beta serine/threonine protein kinas... 242 1e-62 UniRef50_A0CFD9 Cluster: Chromosome undetermined scaffold_175, w... 241 1e-62 UniRef50_Q96BR1 Cluster: Serine/threonine-protein kinase Sgk3; n... 241 2e-62 UniRef50_A0BY36 Cluster: Chromosome undetermined scaffold_136, w... 240 4e-62 UniRef50_Q33DX3 Cluster: Putative cyclic AMP-dependent protein k... 240 4e-62 UniRef50_A7TPV4 Cluster: Putative uncharacterized protein; n=1; ... 240 4e-62 UniRef50_UPI000065EC1B Cluster: Homolog of Fugu rubripes "Protei... 239 7e-62 UniRef50_Q7QUE9 Cluster: GLP_59_15138_16382; n=2; Giardia intest... 239 7e-62 UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome s... 239 9e-62 UniRef50_Q4PH11 Cluster: Putative uncharacterized protein; n=1; ... 239 9e-62 UniRef50_UPI0000499868 Cluster: protein kinase; n=1; Entamoeba h... 238 1e-61 UniRef50_Q4N4B2 Cluster: CAMP-dependent protein kinase catalytic... 238 1e-61 UniRef50_Q10364 Cluster: Serine/threonine-protein kinase sck2; n... 238 1e-61 UniRef50_Q26334 Cluster: Serine/threonine protein kinase; n=2; E... 238 2e-61 UniRef50_A0E7B2 Cluster: Chromosome undetermined scaffold_80, wh... 237 3e-61 UniRef50_A0DUX2 Cluster: Chromosome undetermined scaffold_65, wh... 237 3e-61 UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme ... 235 9e-61 UniRef50_UPI00006CC8B4 Cluster: Protein kinase domain containing... 234 3e-60 UniRef50_A0CNT4 Cluster: Chromosome undetermined scaffold_22, wh... 234 3e-60 UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5; ... 233 6e-60 UniRef50_P21901 Cluster: Spermatozoon-associated protein kinase;... 233 6e-60 UniRef50_A2DS63 Cluster: AGC family protein kinase; n=3; Trichom... 232 1e-59 UniRef50_A0DVL2 Cluster: Chromosome undetermined scaffold_66, wh... 232 1e-59 UniRef50_Q8MYF1 Cluster: Similar to Dictyostelium discoideum (Sl... 231 2e-59 UniRef50_Q4SYX7 Cluster: Chromosome 21 SCAF11909, whole genome s... 230 4e-59 UniRef50_A2F9U6 Cluster: AGC family protein kinase; n=1; Trichom... 229 8e-59 UniRef50_P50530 Cluster: Serine/threonine-protein kinase sck1; n... 229 8e-59 UniRef50_Q22RI5 Cluster: Protein kinase domain containing protei... 229 1e-58 UniRef50_P34885 Cluster: Protein kinase C-like 1B; n=4; Bilateri... 229 1e-58 UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2; End... 228 1e-58 UniRef50_O61225 Cluster: Serine/Threonine protein kinase; n=1; S... 228 1e-58 UniRef50_Q9UBS0 Cluster: Ribosomal protein S6 kinase beta-2; n=6... 228 1e-58 UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, wh... 228 2e-58 UniRef50_Q4DL90 Cluster: Rac serine-threonine kinase, putative; ... 227 2e-58 UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform... 227 4e-58 UniRef50_A0DTL3 Cluster: Chromosome undetermined scaffold_63, wh... 227 4e-58 UniRef50_Q9UK32 Cluster: Ribosomal protein S6 kinase alpha-6; n=... 227 4e-58 UniRef50_UPI0000499138 Cluster: hypothetical protein 53.t00028; ... 226 7e-58 UniRef50_A2FLX7 Cluster: AGC family protein kinase; n=4; Trichom... 225 9e-58 UniRef50_Q6UB97 Cluster: Protein kinase C 1; n=7; Dikarya|Rep: P... 225 9e-58 UniRef50_UPI00006607B3 Cluster: RAC-beta serine/threonine-protei... 225 1e-57 UniRef50_Q234E6 Cluster: Protein kinase domain containing protei... 225 1e-57 UniRef50_O96997 Cluster: Protein kinase C; n=2; Tetractinomorpha... 225 2e-57 UniRef50_UPI0001509D2B Cluster: Protein kinase C terminal domain... 224 2e-57 UniRef50_A2BIH5 Cluster: Novel protein similar to vertebrate pro... 224 2e-57 UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101, w... 224 2e-57 UniRef50_Q0UME1 Cluster: Putative uncharacterized protein; n=1; ... 223 4e-57 UniRef50_O62570 Cluster: Protein kinase C-related kinase; n=1; S... 223 7e-57 UniRef50_UPI00006CB12C Cluster: Protein kinase domain containing... 222 9e-57 UniRef50_Q7R5X8 Cluster: GLP_81_97826_96747; n=2; Giardia intest... 222 9e-57 UniRef50_Q245J7 Cluster: Protein kinase domain containing protei... 222 9e-57 UniRef50_O61224 Cluster: Serine/Threonine protein kinase; n=1; S... 222 9e-57 UniRef50_Q6C292 Cluster: Similar to sp|P24583 Saccharomyces cere... 222 9e-57 UniRef50_P23443 Cluster: Ribosomal protein S6 kinase beta-1 (EC ... 222 9e-57 UniRef50_A2EEZ5 Cluster: AGC family protein kinase; n=2; Trichom... 222 1e-56 UniRef50_Q5QFC4 Cluster: EnvDll2-01; n=1; Oikopleura dioica|Rep:... 221 2e-56 UniRef50_Q22HC2 Cluster: Protein kinase domain containing protei... 221 2e-56 UniRef50_UPI0000D5755E Cluster: PREDICTED: similar to ribosomal ... 221 3e-56 UniRef50_Q24DD1 Cluster: Protein kinase domain containing protei... 220 4e-56 UniRef50_Q16QY2 Cluster: Ribosomal protein S6 kinase, 90kD, poly... 220 4e-56 UniRef50_UPI00006CB3D2 Cluster: Protein kinase domain containing... 220 5e-56 UniRef50_P16911 Cluster: Protein kinase DC1; n=5; Sophophora|Rep... 220 5e-56 UniRef50_Q8MUA6 Cluster: Protein kinase C-related kinase; n=1; H... 219 6e-56 UniRef50_Q23YB5 Cluster: Protein kinase domain containing protei... 219 6e-56 UniRef50_A0DLX8 Cluster: Chromosome undetermined scaffold_56, wh... 219 6e-56 UniRef50_Q22LX8 Cluster: Protein kinase domain containing protei... 219 8e-56 UniRef50_A2ELF7 Cluster: AGC family protein kinase; n=4; Trichom... 219 8e-56 UniRef50_A2D9C1 Cluster: AGC family protein kinase; n=4; Trichom... 219 8e-56 UniRef50_O42632 Cluster: Protein kinase C-like; n=14; Fungi|Rep:... 219 1e-55 UniRef50_Q00078 Cluster: Protein kinase C-like; n=8; Eurotiomyce... 219 1e-55 UniRef50_A7SL27 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 218 1e-55 UniRef50_A6QRT1 Cluster: Serine/threonine-protein kinase psk1; n... 218 1e-55 UniRef50_Q16513 Cluster: Serine/threonine-protein kinase N2; n=4... 218 1e-55 UniRef50_UPI00015B57E6 Cluster: PREDICTED: similar to protein ki... 217 2e-55 UniRef50_O17874 Cluster: Putative uncharacterized protein; n=2; ... 217 2e-55 UniRef50_UPI000150AAA4 Cluster: Protein kinase domain containing... 217 3e-55 UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative... 217 4e-55 UniRef50_A2F0I9 Cluster: AGC family protein kinase; n=1; Trichom... 217 4e-55 UniRef50_Q16512 Cluster: Serine/threonine-protein kinase N1; n=2... 217 4e-55 UniRef50_O75582 Cluster: Ribosomal protein S6 kinase alpha-5; n=... 217 4e-55 UniRef50_A0DDH0 Cluster: Chromosome undetermined scaffold_46, wh... 216 6e-55 UniRef50_P24723 Cluster: Protein kinase C eta type; n=44; Eumeta... 216 6e-55 UniRef50_A0E8L1 Cluster: Chromosome undetermined scaffold_83, wh... 216 8e-55 UniRef50_A0BD03 Cluster: Chromosome undetermined scaffold_10, wh... 216 8e-55 UniRef50_Q8C050 Cluster: Ribosomal protein S6 kinase alpha-5; n=... 216 8e-55 UniRef50_P83099 Cluster: Putative protein kinase C delta type ho... 216 8e-55 UniRef50_A1Z7T1 Cluster: CG2049-PC, isoform C; n=7; Fungi/Metazo... 215 1e-54 UniRef50_Q6AX33 Cluster: Microtubule-associated serine/threonine... 215 1e-54 UniRef50_Q62074 Cluster: Protein kinase C iota type; n=26; Eumet... 215 1e-54 UniRef50_P41743 Cluster: Protein kinase C iota type; n=97; Bilat... 215 1e-54 UniRef50_Q21694 Cluster: Putative uncharacterized protein; n=2; ... 215 1e-54 UniRef50_A0BJU7 Cluster: Chromosome undetermined scaffold_110, w... 215 1e-54 UniRef50_A4RL90 Cluster: Putative uncharacterized protein; n=1; ... 215 1e-54 UniRef50_P36582 Cluster: Protein kinase C-like 1; n=2; Schizosac... 215 1e-54 UniRef50_Q02156 Cluster: Protein kinase C epsilon type; n=34; Co... 215 1e-54 UniRef50_Q22A18 Cluster: Protein kinase domain containing protei... 215 2e-54 UniRef50_A2EY79 Cluster: AGC family protein kinase; n=1; Trichom... 215 2e-54 UniRef50_A2E5K8 Cluster: AGC family protein kinase; n=1; Trichom... 215 2e-54 UniRef50_A0DZB2 Cluster: Chromosome undetermined scaffold_7, who... 215 2e-54 UniRef50_A2E8A4 Cluster: AGC family protein kinase; n=1; Trichom... 214 3e-54 UniRef50_A2DV83 Cluster: AGC family protein kinase; n=1; Trichom... 213 4e-54 UniRef50_A0DPW4 Cluster: Chromosome undetermined scaffold_6, who... 213 4e-54 UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, wh... 213 4e-54 UniRef50_A6RHI7 Cluster: Serine/threonine-protein kinase Sgk2; n... 213 4e-54 UniRef50_Q9V3I5 Cluster: Chromosomal serine/threonine-protein ki... 213 4e-54 UniRef50_Q584T1 Cluster: Rac serine-threonine kinase, putative; ... 213 5e-54 UniRef50_A2ECT2 Cluster: AGC family protein kinase; n=3; Trichom... 213 5e-54 UniRef50_UPI00006CDDB0 Cluster: Protein kinase domain containing... 213 7e-54 UniRef50_UPI00006CB393 Cluster: Protein kinase domain containing... 213 7e-54 UniRef50_Q4SG88 Cluster: Chromosome 17 SCAF14597, whole genome s... 213 7e-54 UniRef50_A0E8C9 Cluster: Chromosome undetermined scaffold_82, wh... 213 7e-54 UniRef50_P87253 Cluster: Protein kinase C-like; n=6; Pezizomycot... 213 7e-54 UniRef50_P34722 Cluster: Protein kinase C-like 1; n=3; Caenorhab... 213 7e-54 UniRef50_Q23PX4 Cluster: Protein kinase domain containing protei... 212 9e-54 UniRef50_A2DW86 Cluster: AGC family protein kinase; n=1; Trichom... 212 9e-54 UniRef50_A0DTA2 Cluster: Chromosome undetermined scaffold_62, wh... 212 9e-54 UniRef50_A0BPA1 Cluster: Chromosome undetermined scaffold_12, wh... 212 9e-54 UniRef50_Q86ZV2 Cluster: Protein kinase C; n=1; Pichia pastoris|... 212 9e-54 UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14; Ap... 212 1e-53 UniRef50_Q04759 Cluster: Protein kinase C theta type; n=20; Eute... 212 1e-53 UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2; Eim... 211 2e-53 UniRef50_A0EIN6 Cluster: Chromosome undetermined scaffold_99, wh... 211 2e-53 UniRef50_A0BN99 Cluster: Chromosome undetermined scaffold_118, w... 211 2e-53 UniRef50_Q8TFJ3 Cluster: Protein kinase A catalytic subunit; n=1... 211 2e-53 UniRef50_A1CKA9 Cluster: Serine/threonine protein kinase, putati... 211 2e-53 UniRef50_UPI00006CD5AE Cluster: Protein kinase domain containing... 211 2e-53 UniRef50_A0CC53 Cluster: Chromosome undetermined scaffold_166, w... 211 2e-53 UniRef50_UPI000069F1C6 Cluster: UPI000069F1C6 related cluster; n... 210 3e-53 UniRef50_Q24FD5 Cluster: Protein kinase domain containing protei... 210 3e-53 UniRef50_UPI00015A51B8 Cluster: Protein kinase C delta type (EC ... 210 4e-53 UniRef50_UPI000065FBEC Cluster: Ribosomal protein S6 kinase alph... 210 4e-53 UniRef50_Q4RM42 Cluster: Chromosome 10 SCAF15019, whole genome s... 210 4e-53 UniRef50_A0BQE1 Cluster: Chromosome undetermined scaffold_120, w... 210 4e-53 UniRef50_P43057 Cluster: Protein kinase C-like 1; n=4; Saccharom... 210 4e-53 UniRef50_Q91948 Cluster: PKN; n=3; Euteleostomi|Rep: PKN - Xenop... 210 5e-53 UniRef50_A2EX40 Cluster: AGC family protein kinase; n=4; Trichom... 210 5e-53 UniRef50_Q02956 Cluster: Protein kinase C zeta type; n=60; Bilat... 210 5e-53 UniRef50_Q1MX42 Cluster: Protein kinase C, delta V; n=9; Euteleo... 209 7e-53 UniRef50_P90980 Cluster: Protein kinase C-like 2; n=49; Eumetazo... 209 7e-53 UniRef50_Q4RZQ9 Cluster: Chromosome 18 SCAF14786, whole genome s... 209 9e-53 UniRef50_Q7PRV3 Cluster: ENSANGP00000020017; n=1; Anopheles gamb... 209 9e-53 UniRef50_Q6CBU3 Cluster: Yarrowia lipolytica chromosome C of str... 209 9e-53 UniRef50_A5DM82 Cluster: Putative uncharacterized protein; n=1; ... 209 9e-53 UniRef50_UPI00006CFE83 Cluster: Protein kinase domain containing... 208 1e-52 UniRef50_A0BNJ0 Cluster: Chromosome undetermined scaffold_118, w... 208 1e-52 UniRef50_Q24GE7 Cluster: Protein kinase domain containing protei... 208 2e-52 UniRef50_A0E0G1 Cluster: Chromosome undetermined scaffold_71, wh... 208 2e-52 UniRef50_Q6BHW6 Cluster: Debaryomyces hansenii chromosome G of s... 208 2e-52 UniRef50_P36583 Cluster: Protein kinase C-like 2; n=1; Schizosac... 208 2e-52 UniRef50_UPI00015B57A5 Cluster: PREDICTED: similar to CG10261-PE... 208 2e-52 UniRef50_UPI0000499007 Cluster: hypothetical protein 139.t00021;... 208 2e-52 UniRef50_A2DA20 Cluster: AGC family protein kinase; n=2; Trichom... 208 2e-52 UniRef50_UPI00015B53AD Cluster: PREDICTED: similar to RHO kinase... 207 3e-52 UniRef50_O62569 Cluster: Serine/Threonine protein kinase; n=1; S... 207 3e-52 UniRef50_UPI0000499488 Cluster: hypothetical protein 137.t00011;... 207 4e-52 UniRef50_Q69G16 Cluster: Protein kinase C type beta; n=2; Bilate... 207 4e-52 UniRef50_O75116 Cluster: Rho-associated protein kinase 2; n=115;... 206 5e-52 UniRef50_UPI0000D562F1 Cluster: PREDICTED: similar to CG3324-PA;... 206 6e-52 UniRef50_UPI00006CBA83 Cluster: Protein kinase domain containing... 206 6e-52 UniRef50_Q4SK04 Cluster: Chromosome 10 SCAF14571, whole genome s... 205 1e-51 UniRef50_A0D8K8 Cluster: Chromosome undetermined scaffold_41, wh... 204 2e-51 UniRef50_Q05655 Cluster: Protein kinase C delta type; n=61; Eume... 204 2e-51 UniRef50_UPI00015B4E6B Cluster: PREDICTED: hypothetical protein;... 204 3e-51 UniRef50_UPI000069DCCB Cluster: UPI000069DCCB related cluster; n... 204 3e-51 UniRef50_A2E224 Cluster: AGC family protein kinase; n=1; Trichom... 204 3e-51 UniRef50_A2DL59 Cluster: AGC family protein kinase; n=1; Trichom... 204 3e-51 UniRef50_A0E888 Cluster: Chromosome undetermined scaffold_82, wh... 204 3e-51 UniRef50_A0BQV0 Cluster: Chromosome undetermined scaffold_121, w... 204 3e-51 UniRef50_P13677 Cluster: Protein kinase C, eye isozyme (EC 2.7.1... 204 3e-51 UniRef50_Q4RRU3 Cluster: Chromosome 7 SCAF15001, whole genome sh... 203 4e-51 UniRef50_A2E474 Cluster: AGC family protein kinase; n=1; Trichom... 203 4e-51 UniRef50_A0DCJ0 Cluster: Chromosome undetermined scaffold_45, wh... 203 4e-51 UniRef50_A0CUG4 Cluster: Chromosome undetermined scaffold_28, wh... 203 4e-51 UniRef50_Q6P5Z2 Cluster: Serine/threonine-protein kinase N3; n=2... 203 4e-51 UniRef50_A2E8U1 Cluster: AGC family protein kinase; n=1; Trichom... 203 6e-51 UniRef50_A0CP93 Cluster: Chromosome undetermined scaffold_23, wh... 203 6e-51 UniRef50_Q4SLK1 Cluster: Chromosome 15 SCAF14556, whole genome s... 202 8e-51 UniRef50_A2FIJ5 Cluster: AGC family protein kinase; n=1; Trichom... 202 8e-51 UniRef50_A0DYT2 Cluster: Chromosome undetermined scaffold_7, who... 202 8e-51 UniRef50_A5DZ73 Cluster: Putative uncharacterized protein; n=1; ... 202 8e-51 UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|R... 202 1e-50 UniRef50_Q23DN8 Cluster: Cyclic nucleotide-binding domain contai... 202 1e-50 UniRef50_A2EE93 Cluster: AGC family protein kinase; n=1; Trichom... 202 1e-50 UniRef50_UPI0000519F68 Cluster: PREDICTED: similar to cGMP-depen... 201 2e-50 UniRef50_Q4SLR2 Cluster: Chromosome 15 SCAF14556, whole genome s... 201 2e-50 UniRef50_Q4S6S5 Cluster: Chromosome 14 SCAF14723, whole genome s... 201 2e-50 UniRef50_Q5CWD4 Cluster: Cyclic nucleotide (CGMP)-dependent prot... 201 2e-50 UniRef50_UPI00006CFF91 Cluster: Protein kinase domain containing... 201 2e-50 UniRef50_A2G3R6 Cluster: AGC family protein kinase; n=3; Trichom... 201 2e-50 UniRef50_Q5KM47 Cluster: CAMP-dependent protein kinase, putative... 201 2e-50 UniRef50_Q8SRK8 Cluster: Probable cAMP-dependent protein kinase ... 201 2e-50 UniRef50_Q4T638 Cluster: Chromosome undetermined SCAF8942, whole... 200 3e-50 UniRef50_P05129 Cluster: Protein kinase C gamma type; n=98; Eume... 200 3e-50 UniRef50_UPI00006CF9D0 Cluster: Protein kinase domain containing... 200 4e-50 UniRef50_UPI00004999BB Cluster: protein kinase; n=3; Entamoeba h... 200 5e-50 UniRef50_Q59EH6 Cluster: 3-phosphoinositide dependent protein ki... 200 5e-50 UniRef50_O15530 Cluster: 3-phosphoinositide-dependent protein ki... 200 5e-50 UniRef50_Q23NJ5 Cluster: Protein kinase domain containing protei... 199 9e-50 UniRef50_A0C5F6 Cluster: Chromosome undetermined scaffold_15, wh... 199 9e-50 UniRef50_P25098 Cluster: Beta-adrenergic receptor kinase 1; n=65... 199 9e-50 UniRef50_Q5SP91 Cluster: Novel protein similar to rho-associated... 198 1e-49 UniRef50_UPI00006A0EC2 Cluster: UPI00006A0EC2 related cluster; n... 198 2e-49 UniRef50_UPI00006CFBB4 Cluster: Protein kinase domain containing... 198 2e-49 UniRef50_A0DZS8 Cluster: Chromosome undetermined scaffold_70, wh... 198 2e-49 UniRef50_A0CSN3 Cluster: Chromosome undetermined scaffold_26, wh... 198 2e-49 UniRef50_Q54PK9 Cluster: Putative uncharacterized protein pdkB; ... 197 3e-49 UniRef50_A2FNQ5 Cluster: AGC family protein kinase; n=1; Trichom... 197 4e-49 UniRef50_A0C512 Cluster: Chromosome undetermined scaffold_15, wh... 197 4e-49 UniRef50_A7TMA2 Cluster: Putative uncharacterized protein; n=1; ... 197 4e-49 UniRef50_A2G1Q9 Cluster: AGC family protein kinase; n=1; Trichom... 196 5e-49 UniRef50_Q12706 Cluster: Serine/threonine-protein kinase psk1; n... 196 5e-49 UniRef50_A2FMG9 Cluster: AGC family protein kinase; n=2; Trichom... 196 7e-49 UniRef50_A2FDD2 Cluster: AGC family protein kinase; n=2; Trichom... 196 7e-49 UniRef50_A2EWI0 Cluster: AGC family protein kinase; n=2; Trichom... 196 7e-49 UniRef50_A2DB15 Cluster: AGC family protein kinase; n=1; Trichom... 196 7e-49 UniRef50_Q4RPP3 Cluster: Chromosome 12 SCAF15007, whole genome s... 196 9e-49 UniRef50_A0E1G0 Cluster: Chromosome undetermined scaffold_73, wh... 196 9e-49 UniRef50_A0C3V8 Cluster: Chromosome undetermined scaffold_148, w... 196 9e-49 UniRef50_P24583 Cluster: Protein kinase C-like 1; n=5; Ascomycot... 195 1e-48 UniRef50_A0EEZ4 Cluster: Chromosome undetermined scaffold_92, wh... 195 2e-48 UniRef50_UPI00006CFC59 Cluster: Protein kinase domain containing... 194 2e-48 UniRef50_A0EFE8 Cluster: Chromosome undetermined scaffold_93, wh... 194 2e-48 UniRef50_Q9BMX6 Cluster: Phosphoinositide-dependent protein kina... 194 3e-48 UniRef50_A0DBI7 Cluster: Chromosome undetermined scaffold_44, wh... 194 3e-48 UniRef50_A0D680 Cluster: Chromosome undetermined scaffold_39, wh... 194 3e-48 UniRef50_UPI0000E4822C Cluster: PREDICTED: similar to KIAA0619 p... 194 3e-48 UniRef50_UPI00006A08A1 Cluster: Serine/threonine-protein kinase ... 194 3e-48 UniRef50_Q3SEP0 Cluster: CGMP-dependent protein kinase 8-2; n=8;... 193 5e-48 UniRef50_Q23TE4 Cluster: Protein kinase domain containing protei... 193 5e-48 UniRef50_Q9W1B0 Cluster: CG4012-PA; n=3; Sophophora|Rep: CG4012-... 193 6e-48 UniRef50_Q16IB8 Cluster: Myotonin-protein kinase; n=3; cellular ... 193 6e-48 UniRef50_A2DP41 Cluster: AGC family protein kinase; n=1; Trichom... 193 6e-48 UniRef50_Q4Q7M5 Cluster: Rac serine-threonine kinase, putative; ... 192 1e-47 UniRef50_A0BSF2 Cluster: Chromosome undetermined scaffold_125, w... 192 1e-47 UniRef50_Q6FJ43 Cluster: Similar to sp|P24583 Saccharomyces cere... 192 1e-47 UniRef50_A2ET74 Cluster: AGC family protein kinase; n=1; Trichom... 192 1e-47 UniRef50_A0D329 Cluster: Chromosome undetermined scaffold_36, wh... 192 1e-47 UniRef50_A0C4H5 Cluster: Chromosome undetermined scaffold_149, w... 192 1e-47 UniRef50_A7QZS3 Cluster: Chromosome chr13 scaffold_286, whole ge... 191 2e-47 UniRef50_UPI00006A21D0 Cluster: UPI00006A21D0 related cluster; n... 191 2e-47 UniRef50_Q6BPN3 Cluster: Similar to sp|P38070 Saccharomyces cere... 191 2e-47 UniRef50_A0C6X0 Cluster: Chromosome undetermined scaffold_153, w... 190 3e-47 UniRef50_A2FBN5 Cluster: AGC family protein kinase; n=1; Trichom... 190 4e-47 UniRef50_Q8SSJ0 Cluster: PROTEIN KINASE C; n=1; Encephalitozoon ... 190 4e-47 UniRef50_UPI00006A0113 Cluster: UPI00006A0113 related cluster; n... 190 6e-47 UniRef50_Q4DXB5 Cluster: Protein kinase, putative; n=3; Trypanos... 190 6e-47 UniRef50_UPI00006A16D5 Cluster: UPI00006A16D5 related cluster; n... 189 8e-47 UniRef50_A2EZG8 Cluster: AGC family protein kinase; n=1; Trichom... 189 8e-47 UniRef50_A0EAF2 Cluster: Chromosome undetermined scaffold_86, wh... 189 8e-47 UniRef50_A0E2Q8 Cluster: Chromosome undetermined scaffold_75, wh... 189 8e-47 UniRef50_Q233E6 Cluster: Protein kinase domain containing protei... 188 1e-46 UniRef50_A0C404 Cluster: Chromosome undetermined scaffold_148, w... 188 1e-46 UniRef50_A0BWJ4 Cluster: Chromosome undetermined scaffold_132, w... 188 1e-46 UniRef50_A4R181 Cluster: Putative uncharacterized protein; n=1; ... 188 1e-46 UniRef50_UPI00006CAF21 Cluster: Protein kinase domain containing... 188 2e-46 UniRef50_Q00X68 Cluster: Cyclic nucleotide dependent protein kin... 188 2e-46 UniRef50_Q237P3 Cluster: Protein kinase domain containing protei... 188 2e-46 UniRef50_UPI00006A01A3 Cluster: UPI00006A01A3 related cluster; n... 188 2e-46 UniRef50_Q9XF67 Cluster: 3-phosphoinositide-dependent protein ki... 187 3e-46 UniRef50_Q7PTH7 Cluster: ENSANGP00000010728; n=2; Culicidae|Rep:... 187 4e-46 UniRef50_Q54UZ1 Cluster: Putative uncharacterized protein; n=1; ... 187 4e-46 UniRef50_Q4T9Z5 Cluster: Chromosome undetermined SCAF7480, whole... 186 5e-46 UniRef50_O96942 Cluster: Serine /threonine protein kinase; n=1; ... 186 5e-46 UniRef50_A2FY70 Cluster: AGC family protein kinase; n=1; Trichom... 186 5e-46 UniRef50_A0DTB0 Cluster: Chromosome undetermined scaffold_62, wh... 186 5e-46 UniRef50_A0DDW7 Cluster: Chromosome undetermined scaffold_47, wh... 186 5e-46 UniRef50_Q5VT25 Cluster: Serine/threonine-protein kinase MRCK al... 186 5e-46 UniRef50_UPI0000DB6D76 Cluster: PREDICTED: similar to genghis kh... 186 7e-46 UniRef50_Q22XQ2 Cluster: Protein kinase domain containing protei... 186 7e-46 UniRef50_A0BCG0 Cluster: Chromosome undetermined scaffold_10, wh... 186 7e-46 UniRef50_Q22RR1 Cluster: Protein kinase domain containing protei... 186 9e-46 UniRef50_A2FZ96 Cluster: AGC family protein kinase; n=1; Trichom... 185 2e-45 UniRef50_A0C8J6 Cluster: Chromosome undetermined scaffold_158, w... 185 2e-45 UniRef50_A0BGU9 Cluster: Chromosome undetermined scaffold_107, w... 185 2e-45 UniRef50_Q18846 Cluster: Putative ribosomal protein S6 kinase al... 185 2e-45 UniRef50_UPI000049A425 Cluster: hypothetical protein 134.t00004;... 184 2e-45 UniRef50_A2GEQ5 Cluster: AGC family protein kinase; n=1; Trichom... 184 2e-45 UniRef50_Q6DT37 Cluster: Serine/threonine-protein kinase MRCK ga... 184 2e-45 UniRef50_Q01B06 Cluster: CAMP-dependent protein kinase catalytic... 184 3e-45 UniRef50_A5DT22 Cluster: Putative uncharacterized protein; n=1; ... 184 3e-45 UniRef50_A0BFR1 Cluster: Chromosome undetermined scaffold_104, w... 183 5e-45 UniRef50_A2FYT0 Cluster: AGC family protein kinase; n=2; Trichom... 183 7e-45 UniRef50_A0E5D2 Cluster: Chromosome undetermined scaffold_79, wh... 183 7e-45 UniRef50_A0BCL5 Cluster: Chromosome undetermined scaffold_10, wh... 183 7e-45 UniRef50_Q9FXQ0 Cluster: Cyclic nucreotide dependent protein kin... 182 9e-45 UniRef50_P34100 Cluster: Developmentally-regulated protein kinas... 182 9e-45 UniRef50_Q9VXE3 Cluster: CG9774-PA; n=8; Endopterygota|Rep: CG97... 182 1e-44 UniRef50_A2F8E8 Cluster: AGC family protein kinase; n=1; Trichom... 182 1e-44 UniRef50_A0CPK1 Cluster: Chromosome undetermined scaffold_23, wh... 182 1e-44 UniRef50_P38991 Cluster: Spindle assembly checkpoint kinase; n=5... 182 1e-44 UniRef50_UPI00006CB658 Cluster: Protein kinase domain containing... 182 2e-44 UniRef50_P92199 Cluster: Lethal protein 502; n=2; Caenorhabditis... 181 3e-44 UniRef50_A7TL28 Cluster: Putative uncharacterized protein; n=1; ... 181 3e-44 UniRef50_Q23G03 Cluster: Protein kinase domain containing protei... 180 3e-44 UniRef50_O01583 Cluster: Temporarily assigned gene name protein ... 180 5e-44 UniRef50_A5AA56 Cluster: Putative Rho-associated kinase; n=1; Hy... 180 5e-44 UniRef50_Q5AAN6 Cluster: Likely protein kinase; n=1; Candida alb... 180 5e-44 UniRef50_UPI000065FF34 Cluster: Homolog of Homo sapiens "Protein... 180 6e-44 UniRef50_UPI0000EB1830 Cluster: Serine/threonine-protein kinase ... 180 6e-44 UniRef50_Q9Y7J6 Cluster: Serine/threonine-protein kinase ppk21; ... 180 6e-44 UniRef50_UPI00006A1147 Cluster: UPI00006A1147 related cluster; n... 179 8e-44 UniRef50_UPI000069F567 Cluster: UPI000069F567 related cluster; n... 179 8e-44 UniRef50_UPI00006CC414 Cluster: Protein kinase domain containing... 179 1e-43 UniRef50_Q4T021 Cluster: Chromosome undetermined SCAF11390, whol... 179 1e-43 UniRef50_A0E6L8 Cluster: Chromosome undetermined scaffold_8, who... 177 2e-43 UniRef50_A0DBI9 Cluster: Chromosome undetermined scaffold_44, wh... 177 2e-43 UniRef50_A0EAJ3 Cluster: Chromosome undetermined scaffold_86, wh... 177 3e-43 UniRef50_A0BYR7 Cluster: Chromosome undetermined scaffold_137, w... 177 4e-43 UniRef50_UPI000069DCF9 Cluster: UPI000069DCF9 related cluster; n... 176 6e-43 UniRef50_A0DXD7 Cluster: Chromosome undetermined scaffold_68, wh... 176 6e-43 UniRef50_Q6CPN3 Cluster: Similar to sgd|S0002874 Saccharomyces c... 176 6e-43 UniRef50_Q5DGA7 Cluster: SJCHGC00915 protein; n=1; Schistosoma j... 176 7e-43 UniRef50_Q54WX4 Cluster: Putative uncharacterized protein aurB; ... 176 7e-43 UniRef50_A2EJ98 Cluster: AGC family protein kinase; n=2; Trichom... 176 7e-43 UniRef50_UPI0000F1DBBC Cluster: PREDICTED: hypothetical protein;... 175 1e-42 UniRef50_UPI000065F79D Cluster: Protein kinase C delta type (EC ... 175 2e-42 UniRef50_Q7R3M3 Cluster: GLP_39_70935_69175; n=2; Giardia intest... 175 2e-42 UniRef50_A2GBV0 Cluster: AGC family protein kinase; n=1; Trichom... 175 2e-42 UniRef50_UPI00015B638D Cluster: PREDICTED: similar to aurora kin... 174 2e-42 UniRef50_UPI00006D0072 Cluster: Protein kinase domain containing... 174 2e-42 UniRef50_Q24FU4 Cluster: Protein kinase domain containing protei... 174 3e-42 UniRef50_A0DGQ2 Cluster: Chromosome undetermined scaffold_5, who... 174 3e-42 UniRef50_A0BZI1 Cluster: Chromosome undetermined scaffold_139, w... 174 3e-42 UniRef50_UPI000150AA6C Cluster: Protein kinase domain containing... 173 4e-42 UniRef50_A3KP71 Cluster: Prkcq protein; n=4; Clupeocephala|Rep: ... 173 4e-42 UniRef50_Q21483 Cluster: Putative uncharacterized protein; n=2; ... 173 4e-42 UniRef50_Q6BVA0 Cluster: Spindle assembly checkpoint kinase; n=1... 173 4e-42 UniRef50_UPI00006A17F7 Cluster: UPI00006A17F7 related cluster; n... 173 5e-42 UniRef50_UPI000069D92E Cluster: UPI000069D92E related cluster; n... 173 5e-42 UniRef50_A2FYJ4 Cluster: AGC family protein kinase; n=1; Trichom... 173 5e-42 UniRef50_Q22DW7 Cluster: Protein kinase domain containing protei... 173 7e-42 UniRef50_A7PMI1 Cluster: Chromosome chr14 scaffold_21, whole gen... 172 9e-42 UniRef50_A0D032 Cluster: Chromosome undetermined scaffold_329, w... 172 9e-42 UniRef50_UPI00015B4C4D Cluster: PREDICTED: similar to p90 riboso... 172 1e-41 UniRef50_A0CIE7 Cluster: Chromosome undetermined scaffold_19, wh... 171 2e-41 UniRef50_A0BCA7 Cluster: Chromosome undetermined scaffold_10, wh... 171 2e-41 UniRef50_A0E525 Cluster: Chromosome undetermined scaffold_79, wh... 169 6e-41 UniRef50_Q6C3J2 Cluster: Spindle assembly checkpoint kinase; n=1... 169 6e-41 UniRef50_O22932 Cluster: CBL-interacting serine/threonine-protei... 169 1e-40 UniRef50_UPI0000499714 Cluster: protein kinase; n=3; Entamoeba h... 168 2e-40 UniRef50_A2DH70 Cluster: AGC family protein kinase; n=1; Trichom... 167 3e-40 UniRef50_Q86UX6 Cluster: Serine/threonine-protein kinase 32C; n=... 167 3e-40 UniRef50_A2DBY9 Cluster: CAMK family protein kinase; n=2; Tricho... 167 3e-40 UniRef50_Q9VTY8 Cluster: CG10522-PA; n=4; Sophophora|Rep: CG1052... 167 5e-40 UniRef50_Q7QXR8 Cluster: GLP_399_8255_9553; n=1; Giardia lamblia... 167 5e-40 UniRef50_Q27393 Cluster: Aurora; n=7; Fungi/Metazoa group|Rep: A... 167 5e-40 UniRef50_A0CGU4 Cluster: Chromosome undetermined scaffold_18, wh... 167 5e-40 UniRef50_Q6BIK8 Cluster: Similar to CA1971|CaPKH2 Candida albica... 167 5e-40 UniRef50_A0BR89 Cluster: Chromosome undetermined scaffold_122, w... 166 6e-40 UniRef50_O14578 Cluster: Citron Rho-interacting kinase; n=56; Eu... 166 6e-40 UniRef50_UPI00004D2369 Cluster: UPI00004D2369 related cluster; n... 166 8e-40 UniRef50_Q9W532 Cluster: CG4290-PA; n=8; Coelomata|Rep: CG4290-P... 166 8e-40 UniRef50_A0E1C0 Cluster: Chromosome undetermined scaffold_73, wh... 166 8e-40 UniRef50_UPI0001509E5E Cluster: Streptococcal surface antigen re... 165 1e-39 UniRef50_UPI000069F393 Cluster: UPI000069F393 related cluster; n... 165 1e-39 UniRef50_Q84QE0 Cluster: Avr9/Cf-9 rapidly elicited protein 216;... 165 1e-39 UniRef50_A2EAS8 Cluster: CAMK family protein kinase; n=1; Tricho... 165 1e-39 UniRef50_UPI000069FC08 Cluster: UPI000069FC08 related cluster; n... 165 1e-39 UniRef50_Q4Q898 Cluster: Zinc finger protein kinase-like; n=3; L... 165 1e-39 UniRef50_A0E900 Cluster: Chromosome undetermined scaffold_83, wh... 165 2e-39 UniRef50_Q5C2X7 Cluster: SJCHGC09382 protein; n=1; Schistosoma j... 164 2e-39 UniRef50_Q248B0 Cluster: Protein kinase domain containing protei... 164 2e-39 UniRef50_A0E8Y3 Cluster: Chromosome undetermined scaffold_83, wh... 164 2e-39 UniRef50_A0BT25 Cluster: Chromosome undetermined scaffold_126, w... 164 3e-39 UniRef50_UPI000069E61F Cluster: UPI000069E61F related cluster; n... 163 4e-39 UniRef50_A2DYS1 Cluster: AGC family protein kinase; n=1; Trichom... 163 4e-39 UniRef50_UPI00006CBF34 Cluster: Protein kinase domain containing... 163 6e-39 UniRef50_A2X165 Cluster: Putative uncharacterized protein; n=2; ... 163 6e-39 UniRef50_Q16NS1 Cluster: Citron ser/thr kinase; n=3; Culicidae|R... 163 6e-39 UniRef50_Q6E6E4 Cluster: Protein kinase C; n=1; Antonospora locu... 163 6e-39 UniRef50_UPI000069EAF4 Cluster: UPI000069EAF4 related cluster; n... 163 7e-39 UniRef50_Q96NX5 Cluster: Calcium/calmodulin-dependent protein ki... 163 7e-39 UniRef50_Q54DF2 Cluster: Putative uncharacterized protein mrkA; ... 162 1e-38 UniRef50_Q4Q9K2 Cluster: Serine/threonine-protein kinase, putati... 162 1e-38 UniRef50_A0C2B1 Cluster: Chromosome undetermined scaffold_144, w... 162 1e-38 UniRef50_Q4SL09 Cluster: Chromosome 17 SCAF14563, whole genome s... 162 1e-38 UniRef50_A0DUI6 Cluster: Chromosome undetermined scaffold_64, wh... 162 1e-38 UniRef50_A0BC68 Cluster: Chromosome undetermined scaffold_10, wh... 162 1e-38 UniRef50_A2BFU1 Cluster: Novel protein; n=6; Euteleostomi|Rep: N... 161 2e-38 UniRef50_Q19858 Cluster: Putative uncharacterized protein; n=1; ... 161 2e-38 UniRef50_A2DAR5 Cluster: AGC family protein kinase; n=1; Trichom... 161 2e-38 UniRef50_Q5A3V9 Cluster: Likely protein kinase; n=5; Saccharomyc... 161 2e-38 UniRef50_Q9NRH2 Cluster: SNF-related serine/threonine-protein ki... 161 2e-38 UniRef50_Q6BG36 Cluster: SNF1-related protein kinase, putative; ... 161 3e-38 UniRef50_A2GCT3 Cluster: CAMK family protein kinase; n=1; Tricho... 161 3e-38 UniRef50_UPI00006CCD64 Cluster: Protein kinase domain containing... 160 5e-38 UniRef50_A0DIF4 Cluster: Chromosome undetermined scaffold_51, wh... 160 5e-38 UniRef50_A0D0C4 Cluster: Chromosome undetermined scaffold_33, wh... 160 5e-38 UniRef50_Q6FT84 Cluster: Similar to sp|Q12236 Saccharomyces cere... 160 5e-38 UniRef50_O08679 Cluster: Serine/threonine-protein kinase MARK2; ... 160 5e-38 UniRef50_Q96GD4 Cluster: Serine/threonine-protein kinase 12; n=7... 160 5e-38 UniRef50_UPI000150A7D8 Cluster: Protein kinase domain containing... 159 7e-38 UniRef50_UPI00006A05EC Cluster: UPI00006A05EC related cluster; n... 159 7e-38 UniRef50_Q6DI71 Cluster: Dmpk protein; n=4; Murinae|Rep: Dmpk pr... 159 7e-38 UniRef50_Q5DTG3 Cluster: MKIAA4230 protein; n=16; Bilateria|Rep:... 159 7e-38 UniRef50_Q4QIJ7 Cluster: Serine/threonine kinase, putative; n=13... 159 7e-38 UniRef50_A2DRK1 Cluster: AGC family protein kinase; n=1; Trichom... 159 7e-38 UniRef50_Q9P0L2 Cluster: Serine/threonine-protein kinase MARK1; ... 159 7e-38 UniRef50_UPI000065EE71 Cluster: MAP/microtubule affinity-regulat... 159 9e-38 UniRef50_Q6BFK9 Cluster: SNF1-related protein kinase, putative; ... 159 9e-38 UniRef50_A0DYJ0 Cluster: Chromosome undetermined scaffold_7, who... 159 9e-38 UniRef50_A0DXJ1 Cluster: Chromosome undetermined scaffold_69, wh... 159 9e-38 UniRef50_Q15835 Cluster: Rhodopsin kinase precursor; n=28; Eutel... 159 9e-38 UniRef50_Q00TK7 Cluster: Protein kinase, putative; n=2; Ostreoco... 159 1e-37 UniRef50_Q869W6 Cluster: Similar to Xenopus laevis (African claw... 159 1e-37 UniRef50_A0DYF2 Cluster: Chromosome undetermined scaffold_7, who... 159 1e-37 UniRef50_Q12236 Cluster: Probable serine/threonine-protein kinas... 159 1e-37 UniRef50_O59790 Cluster: Serine/threonine-protein kinase ark1; n... 159 1e-37 UniRef50_UPI00015B41D5 Cluster: PREDICTED: hypothetical protein;... 158 2e-37 UniRef50_UPI00006CBD02 Cluster: Protein kinase domain containing... 158 2e-37 UniRef50_UPI00004D65ED Cluster: UPI00004D65ED related cluster; n... 158 2e-37 UniRef50_Q9FJ55 Cluster: Serine/threonine protein kinase; n=14; ... 158 2e-37 UniRef50_Q21271 Cluster: Aurora/ipl1 related kinase protein 1; n... 158 2e-37 UniRef50_A2EKR5 Cluster: CAMK family protein kinase; n=3; Tricho... 158 2e-37 UniRef50_A2DY61 Cluster: CAMK family protein kinase; n=1; Tricho... 158 2e-37 UniRef50_A0E675 Cluster: Chromosome undetermined scaffold_8, who... 158 2e-37 UniRef50_A0BXP1 Cluster: Chromosome undetermined scaffold_135, w... 158 2e-37 UniRef50_A1DMX3 Cluster: Protein kinase, putative; n=11; Pezizom... 158 2e-37 UniRef50_O88445 Cluster: Serine/threonine-protein kinase 13; n=7... 158 2e-37 UniRef50_UPI000155CD39 Cluster: PREDICTED: similar to Serine/thr... 157 3e-37 UniRef50_UPI0000D55D86 Cluster: PREDICTED: similar to SNF1-like ... 157 3e-37 UniRef50_A7QFL3 Cluster: Chromosome chr8 scaffold_88, whole geno... 157 3e-37 UniRef50_Q3SEM7 Cluster: CGMP-dependent protein kinase 15-1; n=2... 157 3e-37 UniRef50_A2FMX7 Cluster: CAMK family protein kinase; n=2; Tricho... 157 3e-37 UniRef50_A2ET53 Cluster: CAMK family protein kinase; n=1; Tricho... 157 3e-37 UniRef50_P25323 Cluster: Myosin light chain kinase; n=4; Dictyos... 157 3e-37 UniRef50_UPI00003C0E92 Cluster: PREDICTED: similar to CG4290-PA;... 157 4e-37 UniRef50_Q6P954 Cluster: Zgc:73231; n=2; Danio rerio|Rep: Zgc:73... 157 4e-37 UniRef50_A0CDF8 Cluster: Chromosome undetermined scaffold_17, wh... 157 4e-37 UniRef50_Q6FQB9 Cluster: Similar to sp|Q12236 Saccharomyces cere... 157 4e-37 UniRef50_Q6C7R4 Cluster: Similar to sp|P32562 Saccharomyces cere... 157 5e-37 UniRef50_Q753D9 Cluster: Serine/threonine-protein kinase PKH3; n... 157 5e-37 UniRef50_UPI00006CBCB4 Cluster: Protein kinase domain containing... 156 6e-37 >UniRef50_P17612 Cluster: cAMP-dependent protein kinase, alpha-catalytic subunit; n=158; Bilateria|Rep: cAMP-dependent protein kinase, alpha-catalytic subunit - Homo sapiens (Human) Length = 351 Score = 363 bits (894), Expect = 3e-99 Identities = 158/328 (48%), Positives = 232/328 (70%) Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62 KEDF KK+ +D F+ +K +G G++G V LV+ K T ++AMK+++K VV+ Sbjct: 24 KEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKL 83 Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122 +H + EK+ILQ + FPF+V L+ +FKDN LY ++ Y+ GGEMF+++++ G FS+ Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143 Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182 +FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTP 203 Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242 EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS 263 Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302 + K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P PG Sbjct: 264 SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPG 323 Query: 303 DTSNFPEIPQPKLRKVSKYLYEEEFAEF 330 DTSNF + + ++R +EF+EF Sbjct: 324 DTSNFDDYEEEEIRVSINEKCGKEFSEF 351 >UniRef50_P22612 Cluster: cAMP-dependent protein kinase, gamma-catalytic subunit; n=18; Coelomata|Rep: cAMP-dependent protein kinase, gamma-catalytic subunit - Homo sapiens (Human) Length = 351 Score = 350 bits (860), Expect = 3e-95 Identities = 155/326 (47%), Positives = 227/326 (69%) Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64 DF ++ + + D F+ ++ +G G++G V LVR + T ++AMK++ K VV+ Sbjct: 26 DFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQ 85 Query: 65 AKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTK 124 +H++ EK+ILQ I FPF+V L +FKDN YLY ++ Y+ GGEMF+ +Q+ G FS+ Sbjct: 86 VEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHAC 145 Query: 125 FYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEY 184 FYA+QV+LA++YLH +++HRD+KPEN+LID GYL++ DFGF K +K +TWTLCGTPEY Sbjct: 146 FYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEY 205 Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPE 244 LAPE+I SKGY+ +VDWWALG L +EM G PPF+A P ++YEK++ G + P +S + Sbjct: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSD 265 Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304 K+LL+ LLQVD +KR G+L+ G+ +IK+H WF W AI+ +K+ APF+P + PGD Sbjct: 266 LKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDA 325 Query: 305 SNFPEIPQPKLRKVSKYLYEEEFAEF 330 SNF + + +LR +EF+EF Sbjct: 326 SNFDDYEEEELRISINEKCAKEFSEF 351 >UniRef50_Q17JG1 Cluster: Camp-dependent protein kinase catalytic subunit; n=1; Aedes aegypti|Rep: Camp-dependent protein kinase catalytic subunit - Aedes aegypti (Yellowfever mosquito) Length = 405 Score = 345 bits (849), Expect = 7e-94 Identities = 150/332 (45%), Positives = 222/332 (66%), Gaps = 3/332 (0%) Query: 2 LKEDFNKKYSDAPIYDKT-VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVV 60 LK DF KKY++ + D+D++K +G GA+G V L+R K T Y A+K++ K +V Sbjct: 74 LKVDFEKKYNNVKASSGNGLQDYDVLKTLGTGAFGVVKLIRRKNTEEYFALKILSKEKIV 133 Query: 61 ERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSD 120 +H EK+ILQ ++FPF+V ++ FKDN Y+Y ++P++ GGEMF ++K F + Sbjct: 134 RHKQLQHTANEKRILQSVEFPFLVNMECCFKDNSYIYLVMPFVCGGEMFALLRKSKRFGE 193 Query: 121 SLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCG 180 KFY +QV LA+EYLH+ +++RD+KPENILID GY+K+ DFGFCK+++ +TWTLCG Sbjct: 194 EQAKFYGAQVALAIEYLHHMNLIYRDLKPENILIDMKGYVKITDFGFCKLIRDRTWTLCG 253 Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFF--ASDPNKLYEKVLVGSYKCP 238 TPEYLAPE+I SKGY SVDWW+ G L +EM AG+ PF+ +SD L+EK+ G ++ P Sbjct: 254 TPEYLAPEIIQSKGYGKSVDWWSFGILLYEMAAGYTPFYTNSSDHMVLFEKICKGKFRFP 313 Query: 239 ENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPIC 298 + K+L++ +L D ++R G+LK G +IK H WF G +W + + ++ APF+P Sbjct: 314 AGFGGDLKHLIQNILHADLTRRFGNLKNGANDIKQHIWFRGTNWIGLMNMEVSAPFIPKI 373 Query: 299 SSPGDTSNFPEIPQPKLRKVSKYLYEEEFAEF 330 S PGD S F + L+ SK ++ +EFA+F Sbjct: 374 SGPGDASQFDIYDEQDLKIASKCMFIKEFADF 405 >UniRef50_Q9VA47 Cluster: CG12069-PA; n=3; Sophophora|Rep: CG12069-PA - Drosophila melanogaster (Fruit fly) Length = 356 Score = 318 bits (782), Expect = 1e-85 Identities = 151/332 (45%), Positives = 214/332 (64%), Gaps = 3/332 (0%) Query: 2 LKEDFNKKYS-DAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVV 60 L+EDFNKK++ + P +DD++I +G+G++G+V LVR++ + Y+A K + K +V Sbjct: 25 LREDFNKKFATNTPSPSTGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIV 84 Query: 61 ERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSD 120 + H++ EK +L+ + FP V L ++KD LY +LP I GGE+FTY +K F++ Sbjct: 85 KTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTE 144 Query: 121 SLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCG 180 +FYA+QV LALEYLH+C +++RD+KPENI++D NGYLK+ DFGF K ++ +T TLCG Sbjct: 145 KQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVETRTMTLCG 204 Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFA--SDPNKLYEKVLVGSYKCP 238 TPEYL PE+I SK Y SVDWWA G L FE AGH PF A D +Y K+ YK P Sbjct: 205 TPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMP 264 Query: 239 ENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPIC 298 S ++L+ LLQVD SKR G+L G +IK H WF ++W + +Q + AP+VP Sbjct: 265 SYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPYVPNI 324 Query: 299 SSPGDTSNFPEIPQPKLRKVSKYLYEEEFAEF 330 S+P D SNF ++ K +EE FA+F Sbjct: 325 SNPEDISNFDKVSDKPRPKAKTMRHEEAFADF 356 >UniRef50_O13367 Cluster: CAMP-dependent protein kinase catalytic subunit; n=6; Eukaryota|Rep: CAMP-dependent protein kinase catalytic subunit - Ustilago maydis (Smut fungus) Length = 398 Score = 309 bits (758), Expect = 8e-83 Identities = 134/293 (45%), Positives = 202/293 (68%), Gaps = 5/293 (1%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKIT-----FTYHAMKVVEKSVVVERNHAKHLILEKKI 74 + DF++V+ +G G +G V LVR K Y A+KV+ K+ V++ H+ E+ I Sbjct: 74 LSDFEVVETLGTGTFGRVLLVRLKDRDVADRSAYFALKVLAKTDVIKLKQVSHINSERCI 133 Query: 75 LQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILAL 134 L + PF+V + +F+D+ Y ++ Y+ GGE+F+Y+++ G FS + +FY S ++LA+ Sbjct: 134 LTKVDHPFLVNMIASFQDSKNCYMLMEYVVGGEIFSYLRRAGHFSADVARFYISTIVLAI 193 Query: 135 EYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKG 194 EYLH +VV+RD+KPEN+LIDSNGY K+ DFGF K ++ +TWTLCGTPEYLAPE+I G Sbjct: 194 EYLHSNKVVYRDLKPENLLIDSNGYTKITDFGFAKEVEDRTWTLCGTPEYLAPEIIQCSG 253 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 + +VDWW+LG L FEM AG+PPF+ +P +YEK+L G+ PE + P ++L+ LL Sbjct: 254 HGSAVDWWSLGILLFEMLAGYPPFYDPNPILIYEKILAGNLVFPEEIDPLSRDLISSLLT 313 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 D S+R+G+L+GG ++K+H WF+G+DW+A+ +++ P VP PGDTSNF Sbjct: 314 ADRSRRLGNLRGGANDVKNHPWFHGVDWKALQEGRILPPIVPYLGRPGDTSNF 366 >UniRef50_P51817 Cluster: Serine/threonine-protein kinase PRKX; n=54; Eukaryota|Rep: Serine/threonine-protein kinase PRKX - Homo sapiens (Human) Length = 358 Score = 303 bits (744), Expect = 4e-81 Identities = 134/301 (44%), Positives = 201/301 (66%), Gaps = 2/301 (0%) Query: 12 DAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILE 71 + P+Y ++ DFD + +G G +G V LV++K + A+KV+ V+ +H+ E Sbjct: 40 EPPVY--SLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNE 97 Query: 72 KKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVI 131 K +L+ + PF++ L + D +LY ++ Y+ GGE+F+Y++ G FS + FY++++I Sbjct: 98 KSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEII 157 Query: 132 LALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVIT 191 A+EYLH E+V+RD+KPENIL+D +G++KL DFGF K L +TWTLCGTPEYLAPEVI Sbjct: 158 CAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQ 217 Query: 192 SKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKG 251 SKG+ +VDWWALG L FEM +G PPFF +P +Y+K+L G P ++ K+L+K Sbjct: 218 SKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKK 277 Query: 252 LLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIP 311 LL VD ++R+G++K G ++K H WF +DW+A+ +KL P VP + GDTSNF P Sbjct: 278 LLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYP 337 Query: 312 Q 312 + Sbjct: 338 E 338 >UniRef50_P34099 Cluster: cAMP-dependent protein kinase catalytic subunit; n=23; Eukaryota|Rep: cAMP-dependent protein kinase catalytic subunit - Dictyostelium discoideum (Slime mold) Length = 648 Score = 300 bits (737), Expect = 3e-80 Identities = 130/286 (45%), Positives = 198/286 (69%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 +F ++ +G G +G+V+L+++ Y+AMK + K+ VV+ +HL EK IL I P Sbjct: 335 EFKQIRVLGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHP 394 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F+V L AF+D LY + Y+AGGE+FT+++K FS+S KFYA++++LALE+LH Sbjct: 395 FIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQN 454 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSVDW 201 +V+RD+KPEN+LID+ G++K+ DFGF K ++ +T+TLCGTPEYLAPE+I SKG+ +VDW Sbjct: 455 IVYRDLKPENLLIDNQGHIKITDFGFAKRVEDRTFTLCGTPEYLAPEIIQSKGHGKAVDW 514 Query: 202 WALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRI 261 WALG L FEM AG+PPF+ D +Y K+L G P + K+L+K LL D ++R+ Sbjct: 515 WALGILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDLIKRLLTADRTRRL 574 Query: 262 GSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 G+LK G ++K+H WF+ ++W+ ++ ++ PF+P GD+SNF Sbjct: 575 GALKDGALDVKNHRWFSDINWERLYQRRDNGPFIPKIQHQGDSSNF 620 >UniRef50_Q4E4S9 Cluster: Protein kinase A catalytic subunit isoform 1, putative; n=8; Trypanosomatidae|Rep: Protein kinase A catalytic subunit isoform 1, putative - Trypanosoma cruzi Length = 387 Score = 300 bits (736), Expect = 4e-80 Identities = 126/291 (43%), Positives = 203/291 (69%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 DF++ +G G++G V + + K T Y+A+K ++K +++ +H+ EK+IL + P Sbjct: 77 DFEMGDTLGTGSFGRVRIAKLKGTNDYYAVKCLKKREILKMKQVQHISQEKQILMELSHP 136 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F+V + +F+D+ +YF+L ++ GGEMFT+++ G F + + KFY ++++LA EYLH + Sbjct: 137 FIVNMMCSFQDDRRVYFVLEFVVGGEMFTHLRSAGRFPNDVAKFYHAEIVLAFEYLHSKD 196 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSVDW 201 +++RD+KPEN+L+DS G++K+ DFGF K + ++T+TLCGTPEYLAPEVI SKG+ +VDW Sbjct: 197 IIYRDLKPENLLLDSKGHVKVTDFGFAKKVPERTFTLCGTPEYLAPEVIQSKGHGKAVDW 256 Query: 202 WALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRI 261 W +G L +E AG+PPF+ P + YEK+L G +K P ++L+KGLLQ D +KR+ Sbjct: 257 WTMGVLLYEFIAGYPPFYDDTPFRTYEKILSGRFKFPSWFDARARDLVKGLLQTDHTKRL 316 Query: 262 GSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312 G+LKGG+ ++K+H +F+G +W+ ++ + AP SPGDTSNF P+ Sbjct: 317 GTLKGGVADVKNHPYFHGANWEKLYARYYPAPIPVKAKSPGDTSNFERYPE 367 >UniRef50_Q33DX4 Cluster: Putative cyclic AMP-dependent protein kinase catalytic subunit; n=1; Schizophyllum commune|Rep: Putative cyclic AMP-dependent protein kinase catalytic subunit - Schizophyllum commune (Bracket fungus) Length = 432 Score = 299 bits (735), Expect = 5e-80 Identities = 130/307 (42%), Positives = 200/307 (65%), Gaps = 2/307 (0%) Query: 22 DFDIVKAIGNGAYGEVFLVRDK--ITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 DF++ +G G + V +VR + + Y AMKV+ KS +V +H+ E+ IL IQ Sbjct: 108 DFEVRGTLGTGTFARVLIVRHRGRESNNYFAMKVLRKSEIVRLRQVEHVNAERYILSRIQ 167 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+V L F+D+L +Y ++ Y+ GGE+FT++++ F+ +T+FY + +ILAL YLH Sbjct: 168 HPFIVDLFATFQDSLNVYMLMSYVPGGELFTHLRRAQRFTPDVTRFYLATIILALRYLHS 227 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSV 199 +++RD+KPEN+L+DS GYL+L DFGF K++ +TWTLCGTPEYLAPE+I S G+ + Sbjct: 228 FNIIYRDLKPENLLLDSRGYLRLTDFGFAKIVDDRTWTLCGTPEYLAPEIIQSDGHGKAA 287 Query: 200 DWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSK 259 DWWA+G L +EM G+PPFF P +YEK+L G P +M P ++L++ L D +K Sbjct: 288 DWWAVGVLCYEMLVGYPPFFDESPYGIYEKILDGHIHWPRSMDPLSRSLIRAFLNPDRTK 347 Query: 260 RIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPKLRKVS 319 R+G++ GG ++ H WF G+DW A+ ++++AP +P SS DT +F +P P + Sbjct: 348 RLGNMIGGPQDVLEHPWFRGVDWDALERREIMAPIIPHTSSGDDTRHFLRLPLPPAEDMP 407 Query: 320 KYLYEEE 326 +EE+ Sbjct: 408 GLFHEEQ 414 >UniRef50_UPI000155CDCE Cluster: PREDICTED: similar to protein kinase; n=2; Mammalia|Rep: PREDICTED: similar to protein kinase - Ornithorhynchus anatinus Length = 450 Score = 296 bits (727), Expect = 4e-79 Identities = 131/291 (45%), Positives = 193/291 (66%) Query: 27 KAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTL 86 + + G +G V LV+++ Y A+KV+ V+ +H+ EK +L+ + PF++ L Sbjct: 145 RLLSTGTFGRVHLVKERTAKHYFALKVMSIPDVIRLKQEQHVHNEKSVLKEVNHPFLIRL 204 Query: 87 DVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRD 146 + D +LY ++ Y+ GGE+F+Y++ G F++S FY++++I A+EY+H E+V+RD Sbjct: 205 YWTYHDERFLYMLMEYVPGGELFSYLRNMGRFNNSTGLFYSTEIICAIEYIHSKEIVYRD 264 Query: 147 IKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSVDWWALGD 206 +KPENIL+D G++KL DFGF K L KTWTLCGTPEYLAPEVI SKG+ +VDWWALG Sbjct: 265 LKPENILLDKEGHIKLTDFGFAKKLVDKTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGI 324 Query: 207 LSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKG 266 L FEM +G PPFF +P +Y+K+L G P ++ K+L+K LL VD ++R+G++K Sbjct: 325 LIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDLYVKDLIKKLLVVDRTRRLGNMKN 384 Query: 267 GIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPKLRK 317 G ++K H WF +DW+A+ +KL P VP SS GDTSNF P+ K Sbjct: 385 GADDVKRHRWFRSIDWEAVPQRKLKPPIVPKVSSDGDTSNFEAYPEDDWNK 435 >UniRef50_Q8J0I6 Cluster: CAMP-dependent protein kinase A catalytic subunit; n=4; Filobasidiella neoformans|Rep: CAMP-dependent protein kinase A catalytic subunit - Cryptococcus neoformans var. grubii (Filobasidiella neoformans var.grubii) Length = 567 Score = 294 bits (721), Expect = 2e-78 Identities = 123/267 (46%), Positives = 191/267 (71%) Query: 48 YHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGE 107 + AMKV+ KS +V +H+ E+ IL+ ++ PF+V L ++D + +Y +L YI GGE Sbjct: 253 HFAMKVLRKSEIVRLKQVEHINSERIILERVRHPFIVELHATYQDQINVYMLLFYIPGGE 312 Query: 108 MFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGF 167 +F+++++ G FS +T+FY + ++LA+EYLH +++RD+KPEN+L+D +GYL++ DFGF Sbjct: 313 LFSHLRRAGRFSADVTRFYLASIVLAIEYLHSRNIIYRDLKPENLLLDRHGYLRIADFGF 372 Query: 168 CKVLKKKTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLY 227 KV++ +T+TLCGTPEYLAPE++ S+G+ +VDWWALG L FEM AG+PPFF P +Y Sbjct: 373 AKVVQDRTFTLCGTPEYLAPEIVLSQGHGKAVDWWALGILGFEMLAGYPPFFDDHPLGIY 432 Query: 228 EKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFH 287 EK+L G P ++ P K+L++GLL D SKR+G+L+GG ++ H WF G+DW+++ Sbjct: 433 EKILRGDIAFPSHIDPFAKDLIRGLLTADRSKRLGNLRGGAKDVMGHPWFAGVDWRSLER 492 Query: 288 QKLIAPFVPICSSPGDTSNFPEIPQPK 314 +++ AP VP +S GD+ NF P P+ Sbjct: 493 KEIGAPIVPRVASMGDSQNFQRYPPPR 519 >UniRef50_Q2U6J7 Cluster: CAMP-dependent protein kinase catalytic subunit; n=8; Eurotiomycetidae|Rep: CAMP-dependent protein kinase catalytic subunit - Aspergillus oryzae Length = 396 Score = 285 bits (699), Expect = 1e-75 Identities = 132/325 (40%), Positives = 212/325 (65%), Gaps = 13/325 (4%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVR--DKITFT--YHAMKVVEKSVVVERNHAKHLILEKKI 74 TVDDF ++K +G G + V+LVR D+I +A+K++ K+ V++ +H+ E+K Sbjct: 72 TVDDFALLKTLGTGTFARVWLVRLKDEIRQRDKVYALKILRKADVIKLKQVEHVRNERKT 131 Query: 75 LQCIQ-FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133 L + PF+ TL +F D+ LY +L Y GGE+F+Y+++ F+++ KFYA+++ L Sbjct: 132 LSAVAGHPFITTLIASFSDDQSLYMLLDYCPGGEIFSYLRRARRFNENTAKFYAAEITLT 191 Query: 134 LEYLHYCE-VVHRDIKPENILIDSNGYLKLCDFGFCK-VLKKKTWTLCGTPEYLAPEVIT 191 +E+LH E +V+RD+KPENIL+D+ G+++L DFGF K V ++T+TLCGTPEYLAPEVI Sbjct: 192 IEFLHDVEGIVYRDLKPENILLDAEGHIRLVDFGFAKKVDNRETYTLCGTPEYLAPEVIH 251 Query: 192 SKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKG 251 + G+ +VDWWALG L +E G PPF+ +P ++YE+++ G + P+NMSP +N++ Sbjct: 252 NSGHGLAVDWWALGILIYEFLVGQPPFWDQNPMRIYEQIVEGRIRFPQNMSPAAQNIISL 311 Query: 252 LLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIP 311 L + +P++R+G + GG +KSH +F + W +F++++ P +P P DT NF E P Sbjct: 312 LCKTNPTERLGYISGGSARVKSHPFFEDIQWDDLFYRRIKGPIIPRVDHPADTGNFEEYP 371 Query: 312 QPKLRKVSKYL------YEEEFAEF 330 P +R + Y YE F++F Sbjct: 372 DPDVRSQNVYTDDLKKKYEALFSDF 396 >UniRef50_Q8NIL1 Cluster: CAMP-dependent protein kinase catalytic subunit; n=6; Fungi|Rep: CAMP-dependent protein kinase catalytic subunit - Cryptococcus neoformans var. neoformans Length = 516 Score = 284 bits (696), Expect = 3e-75 Identities = 134/316 (42%), Positives = 204/316 (64%), Gaps = 5/316 (1%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 + DF I + +G G++G V LVR + ++A+KV+ K V++ +H E+++L ++ Sbjct: 201 LSDFLIERTLGTGSFGRVHLVRSRHNGRFYAVKVLNKEKVIKMKQVEHTNSEREMLVRVR 260 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+V L F+D LY ++ ++AGGE+F+ ++K F +S+ KFYA++V LAL+YLH Sbjct: 261 HPFLVNLWGTFQDVNNLYMVMDFVAGGELFSLLRKSQRFPNSVAKFYAAEVALALDYLHS 320 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSV 199 ++++RD+KPEN+L+ ++G++K+ +FGF K + TWTLCGTP+YLAPEV+ SKGY+ SV Sbjct: 321 LDIIYRDLKPENLLLGADGHVKVTNFGFAKYVPDITWTLCGTPDYLAPEVVQSKGYNKSV 380 Query: 200 DWWALGDLSFEMEAGHPPFFASD--PNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 DW+ALG L FEM AG+PPFF D P KLYEK++ G + P K LLK LL D Sbjct: 381 DWYALGVLIFEMLAGYPPFFTEDGNPMKLYEKIIAGKVRYPTYFDALAKELLKNLLIGDL 440 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPKLR- 316 +KR G+L+ G +I +H WF +DW ++ +++ AP+VP GD S F + + Sbjct: 441 TKRYGNLRAGSSDIFAHGWFAEVDWDKLYRREIPAPYVPKIDGEGDASQFDRYQEADVSA 500 Query: 317 --KVSKYLYEEEFAEF 330 KV Y+ F EF Sbjct: 501 YGKVGNGPYDHFFTEF 516 >UniRef50_Q20541 Cluster: Cyclic AMP-dependent protein kinase, catalytic subunit; n=5; Caenorhabditis|Rep: Cyclic AMP-dependent protein kinase, catalytic subunit - Caenorhabditis elegans Length = 371 Score = 279 bits (683), Expect = 9e-74 Identities = 122/309 (39%), Positives = 198/309 (64%), Gaps = 1/309 (0%) Query: 2 LKEDFNKKYSDAPIYDK-TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVV 60 L E+ + K S P + ++ + + IG G +G V L RDKIT ++A+KV+ VV Sbjct: 41 LAEETHMKLSITPTRESFSLSQLERIITIGKGTFGRVELARDKITGAHYALKVLNIRRVV 100 Query: 61 ERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSD 120 + +H+ EK++L ++ PF+V + + KD+ +LY I+ ++ GGEMF+Y++ FS+ Sbjct: 101 DMRQTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSN 160 Query: 121 SLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCG 180 S+ +FYAS+++ ALEY+H +V+RD+KPEN+++ G++K+ DFGF K L+ +T+T+CG Sbjct: 161 SMARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTICG 220 Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240 TP+YLAPE + G++ VDWWALG L +EM G PPF +++Y+ ++ K P + Sbjct: 221 TPDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRS 280 Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300 + K+L+K LL+VD ++RIG +K G ++K H WF ++W H ++ P VP Sbjct: 281 FNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYH 340 Query: 301 PGDTSNFPE 309 PGDT NF + Sbjct: 341 PGDTGNFDD 349 >UniRef50_A0BEY5 Cluster: Chromosome undetermined scaffold_103, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_103, whole genome shotgun sequence - Paramecium tetraurelia Length = 524 Score = 276 bits (676), Expect = 7e-73 Identities = 128/304 (42%), Positives = 201/304 (66%), Gaps = 6/304 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 +++DF ++K +G GA+G+V L K T A+K + K ++ R+H ++L E+KIL+ Sbjct: 195 SIEDFTLIKMLGRGAFGKVMLCEKKDTKEIFAIKSLRKEDIISRDHIEYLKTERKILEQT 254 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 Q PF+V+L+ AF +YF++ ++ GGE++T++QK F++ FY+SQV+LALEYLH Sbjct: 255 QHPFLVSLEYAFITQECVYFVMKFMIGGELYTHLQKINKFNEEFALFYSSQVLLALEYLH 314 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK--KTWTLCGTPEYLAPEVITSKGYS 196 +++RD+KPENIL+D GY+ L D+G K L K T ++ GTPEYLAPEVIT +G++ Sbjct: 315 KQGIIYRDLKPENILMDEKGYVALTDYGLAKFLSKGQVTQSIVGTPEYLAPEVITQQGHA 374 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPE--NMSPECKNLLKGLLQ 254 F+ DWW LG L +EM G PFF+ + N+++ ++ K P +++PECK+LL LL+ Sbjct: 375 FTADWWCLGILIYEMLCGKTPFFSENRNQMFRNIVESELKFPSTLHITPECKSLLTSLLK 434 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQP 313 P++R+G+ KG EIK H WF +D+Q + +++ AP +P S D SNF P+I Sbjct: 435 KKPNERLGN-KGDAEEIKKHAWFKRMDFQRLISKEIQAPIIPDLQSATDLSNFNPQILDE 493 Query: 314 KLRK 317 K+ + Sbjct: 494 KIEE 497 >UniRef50_Q9BMY6 Cluster: CAMP-dependent protein kinase catalytic subunit; n=1; Toxoplasma gondii|Rep: CAMP-dependent protein kinase catalytic subunit - Toxoplasma gondii Length = 394 Score = 274 bits (672), Expect = 2e-72 Identities = 122/292 (41%), Positives = 189/292 (64%), Gaps = 3/292 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYH---AMKVVEKSVVVERNHAKHLILEKKIL 75 ++DDF + +G G++G V +V + ++ A+K++ K +V+ +H+ EK+IL Sbjct: 77 SIDDFLFHETVGTGSFGRVCIVDLRGAAGWYPPMALKILSKHKIVKMKQVEHVKDEKRIL 136 Query: 76 QCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135 I+ PF+V L AF+D L+ ++ Y+ GGE+F+++++ + YA+++ LA + Sbjct: 137 SSIEHPFIVNLLAAFQDEKRLFILMEYVNGGELFSHLRRRNCIPTDQARLYAAEITLAFQ 196 Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGY 195 YLH +V+RD+KPEN+LIDS G++K+ DFGF KV+K +TWTLCGT EYLAPE IT +G+ Sbjct: 197 YLHQRHIVYRDLKPENLLIDSQGHIKITDFGFAKVVKDRTWTLCGTHEYLAPESITRRGH 256 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 VDWWALG L FEM AGHPPF +P +Y K++ G + P + K+L+K LL Sbjct: 257 GLPVDWWALGILLFEMLAGHPPFVDENPLGIYRKIIAGKIEFPRSFDYAAKSLVKRLLTH 316 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 DP KR G LK G ++K+H +F G+DW +++ + AP++P P D+S F Sbjct: 317 DPLKRYGCLKDGAEDVKNHKFFKGIDWVKCYNKNIRAPYLPNTRGPQDSSMF 368 >UniRef50_P05986 Cluster: cAMP-dependent protein kinase type 3; n=56; Dikarya|Rep: cAMP-dependent protein kinase type 3 - Saccharomyces cerevisiae (Baker's yeast) Length = 398 Score = 272 bits (667), Expect = 8e-72 Identities = 117/295 (39%), Positives = 195/295 (66%), Gaps = 1/295 (0%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++ DF I++ +G G++G V L+R ++A+K ++K +V+ +H E+++L + Sbjct: 84 SLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIV 143 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF++ + F+D+ ++ ++ YI GGE+F+ ++K F + + KFYA++V LALEYLH Sbjct: 144 SHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLH 203 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFS 198 ++++RD+KPENIL+D NG++K+ DFGF K + T+TLCGTP+Y+APEV+++K Y+ S Sbjct: 204 SKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKS 263 Query: 199 VDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPS 258 VDWW+ G L +EM AG+ PF+ S+ K YE +L K P P+ ++LLK L+ D S Sbjct: 264 VDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLS 323 Query: 259 KRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPF-VPICSSPGDTSNFPEIPQ 312 +R+G+L+ G ++K+H WFN + W+ + + + P+ PI GDTS F P+ Sbjct: 324 ERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPE 378 >UniRef50_P12688 Cluster: Serine/threonine-protein kinase YPK1; n=10; Saccharomycetales|Rep: Serine/threonine-protein kinase YPK1 - Saccharomyces cerevisiae (Baker's yeast) Length = 680 Score = 271 bits (664), Expect = 2e-71 Identities = 127/294 (43%), Positives = 190/294 (64%), Gaps = 5/294 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++DDFD++K IG G++G+V VR K T +A+K + KS +V ++ H + E+ +L + Sbjct: 343 SIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARV 402 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L +F+ LYF+L +I GGE+F ++QK G F S +FY ++++ AL+ LH Sbjct: 403 DCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLH 462 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK---KTWTLCGTPEYLAPEVITSKGY 195 +VV+RD+KPENIL+D G++ LCDFG CK+ K KT T CGTPEYLAPE++ GY Sbjct: 463 KLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGY 522 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 + +VDWW LG L +EM G PP++ D K+Y+K+L P+ + K+LL GLL Sbjct: 523 TKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSR 582 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 DP++R+G G EI++H +F+ L W+ + + I P+ P S+ DTSNF E Sbjct: 583 DPTRRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDE 634 >UniRef50_A6QTK8 Cluster: Serine/threonine-protein kinase PRKX; n=1; Ajellomyces capsulatus NAm1|Rep: Serine/threonine-protein kinase PRKX - Ajellomyces capsulatus NAm1 Length = 412 Score = 270 bits (663), Expect = 3e-71 Identities = 124/310 (40%), Positives = 199/310 (64%), Gaps = 8/310 (2%) Query: 12 DAPIYDKTVDDFDIVKAIGNGAYGEVFLVR-----DKITFTYHAMKVVEKSVVVERNHAK 66 D + ++ DF++++ +G G + V+LVR K +A+KV+ K+ V++ + Sbjct: 79 DTSSSELSIGDFELLQTLGTGTFARVWLVRLLKHTGKFKNGAYALKVLHKADVIKLKQVE 138 Query: 67 HLILEKKILQCIQ-FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKF 125 H+ E + L + PF+ TL F D+L LY +L Y GGE+FT++++ F S +F Sbjct: 139 HVRNEIETLNAVAGHPFITTLVATFTDDLSLYMLLEYCPGGEIFTFLRRARRFDVSTAQF 198 Query: 126 YASQVILALEYLHYCE-VVHRDIKPENILIDSNGYLKLCDFGFCK-VLKKKTWTLCGTPE 183 YA++++L LE+LH + +RD+KPENIL+D++G+LKL DFGF K + ++T+TLCGTPE Sbjct: 199 YAAEIVLILEFLHDVHGIAYRDLKPENILLDADGHLKLVDFGFAKEIWSRETYTLCGTPE 258 Query: 184 YLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSP 243 YLAPEVI + G+ +VDWWALG L +E G PPF+ +P ++Y++++ G + P NM P Sbjct: 259 YLAPEVIHNSGHGLAVDWWALGVLIYEFIVGQPPFWDPNPMRIYKQIVDGVLRFPANMPP 318 Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303 ++++ L Q +PS+R+G +KGG +K H++F G++W I+H+++ P VP SP D Sbjct: 319 AAQDIVSRLCQTNPSERLGHIKGGSARVKQHSFFKGVNWDDIYHRRMKGPIVPRVDSPTD 378 Query: 304 TSNFPEIPQP 313 NF P P Sbjct: 379 AGNFEIYPDP 388 >UniRef50_Q17941 Cluster: Serine/threonine-protein kinase akt-1; n=6; Caenorhabditis|Rep: Serine/threonine-protein kinase akt-1 - Caenorhabditis elegans Length = 541 Score = 270 bits (662), Expect = 3e-71 Identities = 121/301 (40%), Positives = 191/301 (63%), Gaps = 4/301 (1%) Query: 11 SDAPIYDK-TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLI 69 S+A DK T++DFD +K +G G +G+V L ++K T +A+K+++K V++ R H + Sbjct: 180 SEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTL 239 Query: 70 LEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQ 129 E ++LQ + PF+ L +F++ YL F++ + GGE+FT+++K G FS+ +FY ++ Sbjct: 240 TENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAE 299 Query: 130 VILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLA 186 ++LAL YLH C++V+RD+K EN+L+D +G++K+ DFG CK KT T CGTPEYLA Sbjct: 300 IVLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLA 359 Query: 187 PEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECK 246 PEV+ Y VDWW +G + +EM G PF++ D NKL+E ++ G + P +S E + Sbjct: 360 PEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEAR 419 Query: 247 NLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSN 306 LL GLL DP++R+G EI +F +DW+A + +++ P+ P S DTS Sbjct: 420 TLLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSY 479 Query: 307 F 307 F Sbjct: 480 F 480 >UniRef50_Q9P7J8 Cluster: Serine/threonine-protein kinase gad8; n=4; Dikarya|Rep: Serine/threonine-protein kinase gad8 - Schizosaccharomyces pombe (Fission yeast) Length = 569 Score = 269 bits (659), Expect = 8e-71 Identities = 124/292 (42%), Positives = 189/292 (64%), Gaps = 5/292 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+D F+++K +G G++G+V VR + T +A+K ++K+ +V R+ H + E+ +L + Sbjct: 226 TIDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQV 285 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L +F+ LY +L ++ GGE+F ++Q+ G F KFY +++++ALE LH Sbjct: 286 NNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLH 345 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGY 195 V++RD+KPENIL+D G++ LCDFG CK+ K T T CGTPEYLAPE++ GY Sbjct: 346 EFNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGHGY 405 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 + VDWW LG L +EM G PPF+ + N++Y K+L + P+N+ + K+LL GLL Sbjct: 406 TKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDLLSGLLTR 465 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 P KR+GS GG EIK+H +F+ +DW+ + +K+ PF P S DTSNF Sbjct: 466 APEKRLGS--GGAQEIKNHPFFDDIDWKKLCAKKIQPPFKPSVESAIDTSNF 515 >UniRef50_P28178 Cluster: Protein kinase 2; n=2; Dictyostelium discoideum|Rep: Protein kinase 2 - Dictyostelium discoideum (Slime mold) Length = 479 Score = 268 bits (658), Expect = 1e-70 Identities = 123/294 (41%), Positives = 187/294 (63%), Gaps = 4/294 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T DDF+++ IG G++G+V V+ K AMKV+ K ++ R H EK ILQCI Sbjct: 149 TKDDFELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEKTILQCI 208 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L AF+ LY +L ++ GGE+F ++++ G FS+ K YA++++ AL++LH Sbjct: 209 SHPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLH 268 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK--TWTLCGTPEYLAPEVITSKGYS 196 ++V+RD+KPENIL+DS G++ + DFG K ++ T+T CGTPEYLAPEV+ G+ Sbjct: 269 KQDIVYRDLKPENILLDSEGHICITDFGLSKKIETTDGTFTFCGTPEYLAPEVLNGHGHG 328 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 +VDWW+LG L +EM G PPF++ + + +Y+K+L G K P +SPE K+LL+GLL + Sbjct: 329 CAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSLLEGLLTRE 388 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEI 310 KR+G+ GG E+K H WF +DW+ + +++ F P S D S + Sbjct: 389 VDKRLGTKGGG--EVKQHPWFKNIDWEKLDRKEVEVHFKPKVKSGTDISQIDPV 440 >UniRef50_P40376 Cluster: cAMP-dependent protein kinase catalytic subunit; n=1; Schizosaccharomyces pombe|Rep: cAMP-dependent protein kinase catalytic subunit - Schizosaccharomyces pombe (Fission yeast) Length = 512 Score = 268 bits (657), Expect = 1e-70 Identities = 126/290 (43%), Positives = 187/290 (64%), Gaps = 2/290 (0%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 + DF+ ++ +G G++G V LV+ Y+A+KV+EK +V+ +H E+ IL +Q Sbjct: 198 IQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILSRVQ 257 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+ L F+D L+ ++ + GGE+F+ ++K F + + KFYA++VILAL+YLH+ Sbjct: 258 HPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLHH 317 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCK-VLKKKTWTLCGTPEYLAPEVITSKGYSFS 198 ++V+RD+KPEN+L+D G+LK+ DFGF K V TLCGTP+YLAPE+I+ K Y+ + Sbjct: 318 NQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCCTLCGTPDYLAPEIISLKPYNKA 377 Query: 199 VDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPS 258 DWW+LG L FEM AG+PPF++ +P KLYE +L G P SP +LL LLQ D + Sbjct: 378 ADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHLLQRDIT 437 Query: 259 KRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFV-PICSSPGDTSNF 307 R G+LK G +I H WF + W I +K+ P+V PI + GD+S F Sbjct: 438 CRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVPPIQAGMGDSSQF 487 >UniRef50_Q2PJ68 Cluster: Putative uncharacterized protein sgk-1; n=3; Caenorhabditis|Rep: Putative uncharacterized protein sgk-1 - Caenorhabditis elegans Length = 463 Score = 266 bits (652), Expect = 5e-70 Identities = 123/292 (42%), Positives = 190/292 (65%), Gaps = 5/292 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QC 77 T +DFD + IG G++G V+ VR K T +AMK++ K + ++N KH++ E+ +L Sbjct: 131 TANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLINN 190 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 + PF+V+L +F++ LYF+L ++ GGE+F+++Q+ FS+S ++FYA+++ AL YL Sbjct: 191 FKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYL 250 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKG 194 H +++RD+KPEN+L+D GYL L DFG CK K T T CGTPEYLAPE+I K Sbjct: 251 HEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKP 310 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 Y +VDWW LG + +EM G PPF++ D N++Y+K++ + N+S C L+ GLLQ Sbjct: 311 YDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLLQ 370 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSN 306 D SKR+G + +I+ H +F +DW + +++L APF+P + DTSN Sbjct: 371 KDRSKRLGH-RNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSN 421 >UniRef50_Q6CW38 Cluster: Kluyveromyces lactis strain NRRL Y-1140 chromosome B of strain NRRL Y- 1140 of Kluyveromyces lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces lactis strain NRRL Y-1140 chromosome B of strain NRRL Y- 1140 of Kluyveromyces lactis - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 455 Score = 266 bits (651), Expect = 7e-70 Identities = 118/295 (40%), Positives = 194/295 (65%), Gaps = 1/295 (0%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 DF I++ +G G++G V LVR ++AMKV++K+ VV+ +H E+ +L + P Sbjct: 144 DFQILRTLGTGSFGRVHLVRSNHNGRFYAMKVLKKNTVVKLKQVEHTNDERNMLSIVSHP 203 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F++ + F+D+ L+ I+ YI GGE+F+ ++K F + + KFYA++V LALEYLH Sbjct: 204 FIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKG 263 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSVDW 201 +++RD+KPENIL+D NG++KL DFGF K + T+TLCGTP+Y+APEV+++K Y+ SVDW Sbjct: 264 IIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDW 323 Query: 202 WALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRI 261 W+ G L +EM AG+ PF+ S+ K YE +L + P + ++L+ L+ D S+R+ Sbjct: 324 WSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQRL 383 Query: 262 GSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPF-VPICSSPGDTSNFPEIPQPKL 315 G+L+ G ++K+H WF+ + W+ + + + P+ PI + GDTS + P+ ++ Sbjct: 384 GNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEEV 438 >UniRef50_P31751 Cluster: RAC-beta serine/threonine-protein kinase; n=115; root|Rep: RAC-beta serine/threonine-protein kinase - Homo sapiens (Human) Length = 481 Score = 266 bits (651), Expect = 7e-70 Identities = 118/294 (40%), Positives = 187/294 (63%), Gaps = 3/294 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T++DFD +K +G G +G+V LVR+K T Y+AMK++ K V++ ++ H + E ++LQ Sbjct: 148 TMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNT 207 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 + PF+ L AF+ + L F++ Y GGE+F ++ + +F++ +FY ++++ ALEYLH Sbjct: 208 RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH 267 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKGY 195 +VV+RDIK EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+ Y Sbjct: 268 SRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDY 327 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 +VDWW LG + +EM G PF+ D +L+E +L+ + P +SPE K+LL GLL+ Sbjct: 328 GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKK 387 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 DP +R+G E+ H +F ++WQ + +KL+ PF P +S DT F + Sbjct: 388 DPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDD 441 >UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta isozyme; n=49; Bilateria|Rep: cGMP-dependent protein kinase 1, beta isozyme - Homo sapiens (Human) Length = 686 Score = 265 bits (649), Expect = 1e-69 Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78 + DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196 +++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+ Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 551 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254 S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L + Sbjct: 552 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 611 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312 +PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+ Sbjct: 612 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 669 >UniRef50_UPI000049878B Cluster: protein kinase; n=3; Entamoeba histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba histolytica HM-1:IMSS Length = 434 Score = 262 bits (641), Expect = 1e-68 Identities = 134/321 (41%), Positives = 199/321 (61%), Gaps = 10/321 (3%) Query: 1 MLKEDFNKKYSDAPIYDK-TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVV 59 M+ ++ KK + +K +++DFDI+ +G GA+G+V LV+ K +AMK VEK+ + Sbjct: 95 MIGDNKEKKTQEEKEENKISMEDFDIITLLGKGAFGKVMLVKYKKEGKIYAMKTVEKAQI 154 Query: 60 VERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGI-F 118 ++ N +H++ EK +L I PF+V + +F+ +L FIL Y AGGE+F+Y+QK+ Sbjct: 155 IDSNEVEHILSEKVVLSQINNPFLVNMHYSFQTPTHLVFILDYCAGGELFSYLQKHPAGL 214 Query: 119 SDSLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTW-T 177 + KFYA+Q++LALE++H +++RDIKPENIL + +GYL++ DFG K KK T T Sbjct: 215 PEVDVKFYAAQIVLALEHMHSTGIIYRDIKPENILFEKDGYLRMTDFGLAKSTKKGTTNT 274 Query: 178 LCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC 237 CGTPEYLAPEV+ Y+ +DWW LG L +EM PF A +LYE +L K Sbjct: 275 FCGTPEYLAPEVVEGLDYNEYIDWWGLGILIYEMLFTQSPFLAETMEELYENILQREPKY 334 Query: 238 PEN--MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFV 295 P ++ EC N + LL +PSKR+ +IK+H WFNG ++ ++ +KL P+V Sbjct: 335 PSTKPITEECMNFINSLLIKEPSKRLTDPD----QIKTHPWFNGFNFDDLYKKKLTPPYV 390 Query: 296 PICSSPGDTSNF-PEIPQPKL 315 P S DTSNF EI Q ++ Sbjct: 391 PKIQSQTDTSNFDDEITQEEV 411 >UniRef50_Q6CD34 Cluster: Yarrowia lipolytica chromosome C of strain CLIB122 of Yarrowia lipolytica; n=2; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome C of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 657 Score = 262 bits (641), Expect = 1e-68 Identities = 117/292 (40%), Positives = 189/292 (64%), Gaps = 5/292 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++ F+++K +G G +G+V +V+ K T +A+K + K ++ + H + E+ +L I Sbjct: 330 SMQSFELLKVLGKGTFGKVMMVKKKDTHQIYAIKSIYKHYIISTDEVAHTLAERTVLAQI 389 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 + PF+V L +F+ LY L ++ GGE+F ++Q+ F + +FY ++++ ALE LH Sbjct: 390 RNPFIVPLKFSFQSPEKLYLGLAFVNGGELFYHLQRERFFDLNRARFYTAELLCALECLH 449 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGY 195 +V+RD+KPENIL+D G++ LCDFG CK+ ++T T CGTPEY++PE++ +KGY Sbjct: 450 DYNIVYRDLKPENILLDYMGHIVLCDFGLCKLNMTSDERTNTRCGTPEYMSPEILLNKGY 509 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 + SVDWW LG L +EM G PPF++ + NK+Y+++L + P+ M P +++ GLLQ Sbjct: 510 NKSVDWWTLGVLLYEMLTGLPPFYSDNHNKMYQRILNDPLRFPQGMDPTAVDIITGLLQR 569 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +PS+R+G+ GG EIK+H +F +DW + +K APF P P DTSNF Sbjct: 570 EPSERLGA--GGAQEIKAHPFFKDIDWNRLLAKKYSAPFKPRVLDPTDTSNF 619 >UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 17 SCAF14563, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 726 Score = 261 bits (640), Expect = 2e-68 Identities = 128/315 (40%), Positives = 191/315 (60%), Gaps = 7/315 (2%) Query: 5 DFNKKYS--DAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVE 61 D KY +A ++ + DF+I+ +G G +G V LV+ K AMK+++K +V+ Sbjct: 395 DAKAKYEAENAFFFNLNLADFNIINTLGVGGFGRVELVQLKSDENKTFAMKILKKRHIVD 454 Query: 62 RNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDS 121 +H+ EK I+Q F+V L FKD+ YLY ++ GGE++T ++ G F DS Sbjct: 455 TRQQEHIRSEKLIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDS 514 Query: 122 LTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLC 179 T+FY + V+ A YLH +++RD+KPEN+++D GY KL DFGF K + KKTWT C Sbjct: 515 TTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFC 574 Query: 180 GTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKC 237 GTPEY+APE+I +KG+ S D+W+LG L FE+ G PPF DP K Y +L G + Sbjct: 575 GTPEYVAPEIILNKGHDISADYWSLGILMFELLTGSPPFSGPDPMKTYNIILRGIDMIEF 634 Query: 238 PENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPI 297 P+ ++ NL+K L + +PS+R+G+LK G+ +I+ H WF G +W+ + L P +P Sbjct: 635 PKKITKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLKKGTLTPPIIPN 694 Query: 298 CSSPGDTSNFPEIPQ 312 +S DTSNF P+ Sbjct: 695 VTSAIDTSNFDSFPE 709 >UniRef50_Q24HP6 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 529 Score = 261 bits (640), Expect = 2e-68 Identities = 123/295 (41%), Positives = 196/295 (66%), Gaps = 5/295 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 +++DF ++K +G GA+G+V L + K T A+K + K ++ER +H E+KIL+ + Sbjct: 197 SINDFHLIKVLGRGAFGKVMLCQKKDTQDLFAIKSIRKEDIIEREQIEHTKTERKILEQV 256 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 FPF+V L+ AF+ L+F + ++ GGE+F +++K F +S FYASQ++LALEYLH Sbjct: 257 NFPFLVNLEYAFQTKEKLFFAMKFVRGGELFFHLKKDKKFKESRALFYASQILLALEYLH 316 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK--KKTWTLCGTPEYLAPEVITSKGYS 196 ++++RD+KPENIL+D +GY+K+ DFG KVL+ K T +L GTP+YL+PE+I KG++ Sbjct: 317 NQDIIYRDLKPENILLDQDGYVKITDFGLAKVLEKGKLTNSLVGTPDYLSPEIINQKGHN 376 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--MSPECKNLLKGLLQ 254 + D+WA G L +EM G PPFF ++ N +++ + K P + +S EC +++ LL+ Sbjct: 377 RTADYWAFGILIYEMVIGIPPFFNNNQNVMFQLISEKDVKFPTSTPLSKECMDIILRLLK 436 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 DP++R+GS+ G +IK H WF +++ I ++K+ APFVP S D S F E Sbjct: 437 KDPNERLGSV-NGTKDIKEHPWFAKINFDEILNRKVPAPFVPQLKSDTDVSCFDE 490 >UniRef50_O44020 Cluster: PKA protein; n=13; Eukaryota|Rep: PKA protein - Plasmodium falciparum Length = 342 Score = 260 bits (638), Expect = 3e-68 Identities = 113/293 (38%), Positives = 184/293 (62%), Gaps = 1/293 (0%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKI-TFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +DF+ + +G G++G V K + A+K EK ++ + H+ E+KIL I Sbjct: 32 EDFNFICTLGTGSFGRVIFATYKNGNYPPVAIKRFEKCKIIRQKQVDHVFSERKILNYIN 91 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF V L +FKD+ YLY +L ++ GGE FT++++ F + + FYA+Q++L EYL Sbjct: 92 HPFCVNLHGSFKDDSYLYLVLEFVIGGEFFTFLRRNKRFPNDVGCFYAAQIVLIFEYLQS 151 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSV 199 +V+RD KPEN+L+D +G++K+ DFGF K+++ +T+TLCGTPEY APE++ + G+ + Sbjct: 152 LNIVYRDFKPENLLLDKDGFIKMTDFGFAKIVETRTYTLCGTPEYTAPEILLNVGHGKAA 211 Query: 200 DWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSK 259 DWW LG +E+ G PPF+A++P +Y+K+L G P+ + CK+L+K LL D +K Sbjct: 212 DWWTLGIFIYEILVGCPPFYANEPLLIYQKILEGIIYFPKFLDNNCKHLMKKLLSHDLTK 271 Query: 260 RIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312 R G+LK G +K H WF+ +DW + ++ + P+ P + D+SNF + + Sbjct: 272 RYGNLKKGPQNVKEHPWFSNIDWVNLLNKNVEVPYKPKYKNIFDSSNFERVQE 324 >UniRef50_P11792 Cluster: Serine/threonine-protein kinase SCH9; n=2; Saccharomyces cerevisiae|Rep: Serine/threonine-protein kinase SCH9 - Saccharomyces cerevisiae (Baker's yeast) Length = 824 Score = 260 bits (637), Expect = 4e-68 Identities = 130/307 (42%), Positives = 199/307 (64%), Gaps = 8/307 (2%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI--- 78 DF++++ +G G +G+V+ V+ K T +AMKV+ K V+V++N H I E+ IL Sbjct: 411 DFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASK 470 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L +F+ LY + Y++GGE+F ++QK G FS+ KFY ++++LALE+LH Sbjct: 471 SSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLH 530 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTLCGTPEYLAPEVITSK-GYS 196 ++V+RD+KPENIL+D+NG + LCDFG K LK +T T CGT EYLAPE++ + GY+ Sbjct: 531 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYT 590 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-MSPECKNLLKGLLQV 255 VD+W+LG L FEM G PFFA + K+Y+K+ G K P + +S E ++ +KGLL Sbjct: 591 KMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNR 650 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPK 314 +P R+G++ G E+++H +F +DW+A+ +K+ PF P S DTSNF PE Sbjct: 651 NPKHRLGAIDDG-RELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEFTTAS 709 Query: 315 LRKVSKY 321 ++K+ Sbjct: 710 TSYMNKH 716 >UniRef50_P54644 Cluster: RAC family serine/threonine-protein kinase homolog; n=2; Dictyostelium discoideum|Rep: RAC family serine/threonine-protein kinase homolog - Dictyostelium discoideum (Slime mold) Length = 444 Score = 260 bits (637), Expect = 4e-68 Identities = 119/295 (40%), Positives = 182/295 (61%), Gaps = 8/295 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 V DF+++ +G G++G+V VR K T +AMKV+ K +VE N +H + E+ ILQ I Sbjct: 117 VADFELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQKIN 176 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+V L+ +F+ LYFIL Y+ GGE+F ++QK F++ ++Y ++++LALE+LH Sbjct: 177 HPFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHL 236 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCK----VLKKKTWTLCGTPEYLAPEVITSKGY 195 V++RD+KPEN+L+ + G++ + DFG CK KT T CGTPEYLAPEV+ GY Sbjct: 237 SGVIYRDLKPENLLLTNEGHICMTDFGLCKEGLLTPTDKTGTFCGTPEYLAPEVLQGNGY 296 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 VDWW+ G L +EM G PPF+ D ++Y K+++ P +SP+ ++LL+ LL+ Sbjct: 297 GKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLEQLLER 356 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEI 310 DP KR+ IK H +F +DW+ +F + + PF+P DTS + Sbjct: 357 DPEKRLADPN----LIKRHPFFRSIDWEQLFQKNIPPPFIPNVKGSADTSQIDPV 407 >UniRef50_A0CMB4 Cluster: Chromosome undetermined scaffold_21, whole genome shotgun sequence; n=2; Oligohymenophorea|Rep: Chromosome undetermined scaffold_21, whole genome shotgun sequence - Paramecium tetraurelia Length = 333 Score = 260 bits (636), Expect = 5e-68 Identities = 115/292 (39%), Positives = 187/292 (64%), Gaps = 5/292 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T++ F ++K IG G+Y +V LVR T +A+K ++K + ++ +H+++E+ +L Sbjct: 10 TINHFQLIKVIGKGSYAKVLLVRKNDTGKLYAIKALKKKYIQQKRQEEHIMVERNVLVSA 69 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 F++ L +F++ LYF+L Y GGE+F +QK ++ +FY Q+ILA+EYLH Sbjct: 70 NHQFIIKLAFSFQNERKLYFVLEYCPGGELFNLLQKKKKLTEDQCRFYVCQMILAIEYLH 129 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGY 195 +++RD+KPEN+++D++GY+++ DFG K K +++CGTPEYLAPE++ +G+ Sbjct: 130 ENNIIYRDLKPENVILDADGYIRITDFGLSKKNVKQDKDAFSVCGTPEYLAPEILMKQGH 189 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 VDWW LG + FEM G PP++++ +L+E++ K P+N+SP KNLL+GL Q Sbjct: 190 GKPVDWWTLGCIIFEMITGMPPYYSNQRGELFEQIKYQFPKYPQNLSPILKNLLEGLFQK 249 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 P KR+G G +IKSH WF ++W I +++ APF P +S DTS+F Sbjct: 250 QPEKRLG--YNGAGDIKSHPWFEKVNWDYILQKRVEAPFKPKLTSEEDTSHF 299 >UniRef50_Q5K7C2 Cluster: Protein kinase Sch9, putative; n=4; Agaricomycotina|Rep: Protein kinase Sch9, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 817 Score = 258 bits (633), Expect = 1e-67 Identities = 129/301 (42%), Positives = 186/301 (61%), Gaps = 8/301 (2%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC-IQF 80 DF+ +K IG G +G VF VR K T +AMKV+ K +V + H I E+KILQC ++ Sbjct: 382 DFEFLKLIGRGTFGRVFQVRKKDTRRIYAMKVLSKKEIVAKKEVAHTIGERKILQCSLEC 441 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF+V L +F+ + LYF+ Y GGE+F ++QK G FS+ +FY ++++LALE+LH Sbjct: 442 PFLVGLKFSFQTDTELYFVTDYKCGGELFWHLQKEGRFSEDRARFYIAELVLALEHLHKY 501 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEV-ITSKGYS 196 +V+RD+KPENIL+D+ G++ LCDFG K K T T CGT EYLAPEV + KGY Sbjct: 502 NIVYRDLKPENILLDATGHVALCDFGLSKPDLTDDKLTNTFCGTTEYLAPEVLLDEKGYG 561 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-MSPECKNLLKGLLQV 255 VD+W+LG L FEM G PF+A ++Y + G + P+N + + K +KGLL Sbjct: 562 KHVDFWSLGVLLFEMCCGWSPFYAEQTQEMYRLICYGKIRFPKNVIGDDGKQFVKGLLNR 621 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPK 314 +P R+GS +G + E+K H +F +DW ++ +++ PF PI S +NF PE Sbjct: 622 NPQNRLGSHRGAV-ELKEHPFFKNIDWDLLYKKQITPPFKPIVDSDESVANFDPEFTNSS 680 Query: 315 L 315 L Sbjct: 681 L 681 >UniRef50_Q22DD1 Cluster: Protein kinase domain containing protein; n=7; Oligohymenophorea|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 531 Score = 258 bits (631), Expect = 2e-67 Identities = 123/307 (40%), Positives = 196/307 (63%), Gaps = 12/307 (3%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFT-YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++ F+I +G G++G V L + K A+K+++K +V+ +H+ EKKIL I Sbjct: 208 LNQFNIKTTLGTGSFGRVKLAKLKGNEKDVFALKMMKKIEIVKLKQVEHIKSEKKILSQI 267 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 + PF+V L F+D +Y+Y + +++GGE+F+ ++K G FS+ ++ FY +++ LAL+YLH Sbjct: 268 KHPFLVELKGTFQDEIYIYMLFEFVSGGEIFSRLRKEGRFSNDISLFYITEIYLALQYLH 327 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-KKKTWTLCGTPEYLAPEVI--TSKGY 195 +V+RD+KPEN+LID G++K+ DFGF K++ +T+TLCGTPEYLAPE+I GY Sbjct: 328 SQNIVYRDLKPENLLIDKEGHVKIADFGFAKIMDSARTYTLCGTPEYLAPEIIQGAKTGY 387 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 SVDWWALG L FEM +GHPPF+ DP +Y+K++ PE S K+L++ LL Sbjct: 388 GKSVDWWALGVLIFEMLSGHPPFYDCDPMGIYQKIVNSVINFPEFFSLRAKDLVRKLLNP 447 Query: 256 DPSKRIG---SLKGGIYE-----IKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 + R+G + + + IK+H WF G++W I+H+++ +P++P S D S F Sbjct: 448 NIESRLGCQDQILSNVIDQDGNSIKNHKWFKGVNWDKIYHKQIPSPWIPQLKSIDDVSYF 507 Query: 308 PEIPQPK 314 + P+ K Sbjct: 508 EKYPESK 514 >UniRef50_A1CR23 Cluster: CAMP-dependent protein kinase, putative; n=10; Pezizomycotina|Rep: CAMP-dependent protein kinase, putative - Aspergillus clavatus Length = 938 Score = 257 bits (630), Expect = 3e-67 Identities = 129/298 (43%), Positives = 192/298 (64%), Gaps = 10/298 (3%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL---QC 77 +DF I+K IG G +G+V+ V K T +AMKV+ K V++++ H + E+ IL Sbjct: 538 NDFQILKLIGKGTFGQVYQVMKKDTHRIYAMKVLSKKVIIQKKEVAHTLGERNILVRTAM 597 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 PF+V L +F+ LY + Y++GGE+F ++QK G F ++ KFY +++ILAL++L Sbjct: 598 AASPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFQEARAKFYIAELILALQHL 657 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEV-ITSK 193 H ++V+RD+KPENIL+D+NG++ LCDFG K T T CGT EYLAPEV + + Sbjct: 658 HDHDIVYRDLKPENILLDANGHIALCDFGLSKANLTQNDTTNTFCGTTEYLAPEVLLDEQ 717 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-MSPECKNLLKGL 252 GY+ VD+W+LG L FEM G PF+A D ++Y+ + G + P + +S E +N +KGL Sbjct: 718 GYTKMVDFWSLGVLVFEMCCGWSPFYAEDTQQMYKNIAFGKVRFPRDALSTEGRNFVKGL 777 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309 L +PS R+G+ KG E+ +H +FN +DWQA+ +++I PF P S DTSNF PE Sbjct: 778 LNRNPSHRLGA-KGDAKELMAHPFFNDVDWQALARKEVIPPFKPKLKSDTDTSNFDPE 834 >UniRef50_UPI000049A5C0 Cluster: protein kinase; n=1; Entamoeba histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba histolytica HM-1:IMSS Length = 439 Score = 257 bits (629), Expect = 3e-67 Identities = 128/316 (40%), Positives = 201/316 (63%), Gaps = 10/316 (3%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 +DFDI+ IG GA+G+V+LV++K T T AMKV++K V+ER+ +H + EK IL I+ Sbjct: 119 EDFDIISLIGKGAFGKVYLVKNKETQTLFAMKVIQKKQVIERDEVQHSLEEKNILAKIKH 178 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF+V L +F+ ++ L++++ Y GGE+++ ++K ++ TKFYA+Q++LALE+LH Sbjct: 179 PFLVNLYCSFQTSVNLHYVIDYCPGGELYSLMKKEQTMNEKRTKFYAAQLVLALEHLHNQ 238 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGYSF 197 +++RD+KPENILI ++GY++L DFG K+ KT T CGTPEYLAPEVI + Y+ Sbjct: 239 GIIYRDVKPENILICADGYIRLTDFGLSKMGISDNSKTATFCGTPEYLAPEVIQNVAYTN 298 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--MSPECKNLLKGLLQV 255 ++DWW LG L +EM G PF+ + +LY +L E+ +S EC++++ LL+ Sbjct: 299 AIDWWGLGVLIYEMLYGTVPFYDENIQRLYHNILYNQVTFLEHTEISLECRDIISQLLKK 358 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPK 314 +P +R+ IKSH WF+ L W +F +K++ ++P SSP D F EI + Sbjct: 359 NPIERLHETDA----IKSHPWFHDLHWDNLFAKKVLPDYLPQLSSPTDLRYFYKEITEQS 414 Query: 315 LRKVSKYLYEEEFAEF 330 L + + E F +F Sbjct: 415 LSLGGEVVSNELFTDF 430 >UniRef50_Q8INB9 Cluster: RAC serine/threonine-protein kinase; n=8; Bilateria|Rep: RAC serine/threonine-protein kinase - Drosophila melanogaster (Fruit fly) Length = 611 Score = 256 bits (626), Expect = 8e-67 Identities = 113/292 (38%), Positives = 185/292 (63%), Gaps = 3/292 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+++F+ +K +G G +G+V L R+K T +A+K+++K V+++++ H + E ++L+ Sbjct: 262 TLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKST 321 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+++L +F+ N L F++ Y+ GGE+F ++ IF++ T+FY +++I AL YLH Sbjct: 322 NHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLH 381 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGY 195 +++RD+K EN+L+D +G++K+ DFG CK + T T CGTPEYLAPEV+ Y Sbjct: 382 SQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDY 441 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 +VDWW G + +EM G PF+ D + L+ +LV K P N++ E KNLL GLL Sbjct: 442 GQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAK 501 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 DP KR+G K + EI++H +F ++W + +K+ PF P +S DT F Sbjct: 502 DPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYF 553 >UniRef50_Q6PLK2 Cluster: Protein kinase B-like protein; n=4; Plasmodium|Rep: Protein kinase B-like protein - Plasmodium falciparum Length = 446 Score = 255 bits (625), Expect = 1e-66 Identities = 119/290 (41%), Positives = 180/290 (62%), Gaps = 3/290 (1%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 + F+ +K IG G+YG+V LV+ +AMK++ K ++ RN +H +E+ IL+C+ Sbjct: 112 ESFNYLKVIGEGSYGKVMLVKHVQNKKLYAMKILRKENILSRNQLEHTKVERNILKCVSH 171 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF+V + AF+ LYFIL Y GGE+F ++ K FS+ KFY+S++ILALEYLH Sbjct: 172 PFIVKMYYAFQTKQKLYFILEYCPGGELFFHLSKLREFSEETAKFYSSEIILALEYLHDL 231 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197 +++RD+KPEN+L+D G+++L DFG K T +LCGTPEYLAPE+I KG+ Sbjct: 232 NIIYRDLKPENVLLDELGHIRLTDFGLSKEGITETNLTKSLCGTPEYLAPEIIEQKGHGK 291 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 +VDWW+LG + +EM G PF ++ N L+E + P+N+SP+ +LL L + +P Sbjct: 292 AVDWWSLGIMLYEMLTGELPFNNTNRNVLFESIKYQKLNYPKNLSPKAVDLLTKLFEKNP 351 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 KR+GS EIK H +F ++W + ++K+ PF P + D NF Sbjct: 352 KKRLGSGGTDAQEIKKHPFFKNINWNDVLYKKVKPPFKPKLFNQLDLQNF 401 >UniRef50_A5DTG0 Cluster: Serine/threonine-protein kinase YPK1; n=4; Saccharomycetales|Rep: Serine/threonine-protein kinase YPK1 - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 788 Score = 254 bits (623), Expect = 2e-66 Identities = 122/295 (41%), Positives = 187/295 (63%), Gaps = 8/295 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 +++DFD++K IG G++G+V V K T +A+K + K +V R H + E+ +L I Sbjct: 463 SIEDFDLLKVIGKGSFGKVMQVVKKDTRQIYALKTLRKQHIVSRMEVTHTLAERTVLARI 522 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L +F+ LY +L +I GGE+F ++Q+ G F+ ++FY ++++ ALE LH Sbjct: 523 SNPFIVPLKFSFQSPEKLYLVLSFINGGELFWHLQREGKFTMDRSRFYIAELLTALESLH 582 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK---KTWTLCGTPEYLAPEVITSKGY 195 V++RD+KPENIL+D G++ LCDFG CK+ KT T CGTPEYLAPE++ ++GY Sbjct: 583 ELNVIYRDLKPENILLDYQGHIALCDFGLCKLNMSNDDKTNTFCGTPEYLAPELLINQGY 642 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENM-SPECKNLLKGLLQ 254 + SVDWW LG L +EM G PPF+ SD +Y+K+L + P+ + + ++LL LLQ Sbjct: 643 TRSVDWWTLGTLLYEMLTGLPPFYDSDVPTMYKKILQNPLRFPQFLEGTDAQDLLIKLLQ 702 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 DPSKR+ + EIK+H +F +DW + ++ + PF P + DTSNF + Sbjct: 703 KDPSKRLNDAQ----EIKNHPFFKDIDWNKLLNKSYLPPFKPNVENLLDTSNFDQ 753 >UniRef50_A7AWS2 Cluster: cAMP-dependent protein kinase; n=1; Babesia bovis|Rep: cAMP-dependent protein kinase - Babesia bovis Length = 416 Score = 253 bits (620), Expect = 4e-66 Identities = 117/318 (36%), Positives = 194/318 (61%), Gaps = 9/318 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVR----DKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL 75 + +FDI +G G+Y V + K A+K++ K+ V+ HL E+ IL Sbjct: 101 ISNFDIGPIVGTGSYATVCIATLNTGPKSQRATFALKILHKTKVIAERQVMHLRNERHIL 160 Query: 76 QCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135 ++ PF+V +F+D++ +Y +L Y++GGE+F+YI KYG ++ +FY +Q ILA++ Sbjct: 161 STVRHPFIVNYVKSFQDDINVYILLEYVSGGELFSYIYKYGALGHTVARFYTAQAILAID 220 Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGY 195 +LH+ +V+RD+KPEN+L+D +G+++L DFGF K +K KT+T+CGT +YLAPE+ G+ Sbjct: 221 FLHFKGIVYRDLKPENMLLDQDGHIRLVDFGFAKEVKHKTYTVCGTHDYLAPEIFLRCGH 280 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 DWW+LG L +E+ G PPF ASDP+ Y+ L + P ++ E K+ ++ LL V Sbjct: 281 GIEADWWSLGVLVYEILTGVPPFHASDPSATYDLALANHIRFPLSVRVEVKDFIRRLLVV 340 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIP---Q 312 +P KR+G E+ SH +F G+DW + ++L P VP S DT+N+ + P + Sbjct: 341 NPRKRLGGSNSS--ELYSHRFFAGMDWMKLLSKQLKPPIVPRVSGLSDTTNYMQYPDDWR 398 Query: 313 PKLRKVSKYLYEEEFAEF 330 ++++ +E F++F Sbjct: 399 AHDARITRSQQDEYFSDF 416 >UniRef50_Q86ZN6 Cluster: CAMP-dependent protein kinase catalytic subunit; n=7; Pezizomycotina|Rep: CAMP-dependent protein kinase catalytic subunit - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 408 Score = 253 bits (620), Expect = 4e-66 Identities = 126/331 (38%), Positives = 202/331 (61%), Gaps = 24/331 (7%) Query: 20 VDDFDIVKAIGNGAYGEVFLVR------DKITFTYHAMKVVEKSVVVERNHAKHLILEKK 73 + DF V+ +G G + V LVR + A+K++ KS VV+ H+ E+ Sbjct: 72 LSDFKKVRTLGTGTFARVCLVRPSNPQNETERNKVFALKILRKSEVVKLKQIDHVRHERA 131 Query: 74 ILQCIQ-FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVIL 132 IL + FPF+ + +F D+ +LY +L Y+ GGE+F+Y++KY F + + +FYA++++L Sbjct: 132 ILADVSGFPFITNMLASFSDHDFLYIVLDYVPGGELFSYLRKYRRFDEDMARFYAAEIVL 191 Query: 133 ALEYLHYCE--VVHRDIKPENILIDSNGYLKLCDFGFCKVL----------KKKTWTLCG 180 LEYLH + V +RD+KPEN+L+D G++KL DFGF K L ++T+TLCG Sbjct: 192 VLEYLHEAQDGVAYRDLKPENLLLDGQGHIKLVDFGFAKRLGGRRDGDNSGTQETYTLCG 251 Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240 TPEYLAPEVI +KG++ +VDWWALG L +E G+PPF+ +P ++Y++++ P++ Sbjct: 252 TPEYLAPEVIHNKGHTTAVDWWALGILIYEFLTGYPPFWHQNPIEIYKQIVEKPVVFPQD 311 Query: 241 --MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPIC 298 +SP +++++ VD S+R+G++ GG +K H +F G+DW+AI+ +K P +P Sbjct: 312 PPISPNAQDIIRQFCTVDRSRRLGNISGGAARVKEHPFFEGVDWEAIYSRKFPGPILPPI 371 Query: 299 SSPGDTSNFPEIPQPKLRKVSKYLYEEEFAE 329 PGD F P+ V K Y +E A+ Sbjct: 372 RYPGDAQCFDIYPE---EDVGKDPYTDEMAQ 399 >UniRef50_Q2UNA7 Cluster: Ribosomal protein S6 kinase and related proteins; n=5; Pezizomycotina|Rep: Ribosomal protein S6 kinase and related proteins - Aspergillus oryzae Length = 897 Score = 253 bits (620), Expect = 4e-66 Identities = 126/298 (42%), Positives = 190/298 (63%), Gaps = 10/298 (3%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL---QC 77 DDF ++K IG G +G+V+ V+ K T +AMKV+ K V++++ H + E+ IL Sbjct: 500 DDFQVLKLIGKGTFGQVYQVKKKDTRRIYAMKVLSKKVIIQKKEVAHTLGERNILVRTAM 559 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 PF+V L +F+ LY + Y++GGE+F ++QK G F ++ KFY +++ILAL++L Sbjct: 560 AASPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFQEARAKFYIAELILALQHL 619 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEV-ITSK 193 H ++V+RD+KPENIL+D+NG++ LCDFG K T T CGT EYLAPEV + + Sbjct: 620 HEHDIVYRDLKPENILLDANGHIALCDFGLSKANLAQNDTTNTFCGTTEYLAPEVLLDEQ 679 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-MSPECKNLLKGL 252 GY+ VD+W+LG L FEM G PF+A D ++Y+ + G + P + +S E +N +KGL Sbjct: 680 GYTKMVDFWSLGVLVFEMCCGWSPFYAEDTQQMYKNIAFGKVRFPRDALSTEGRNFVKGL 739 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309 L +P R+G+ K E+K H +F+ +DW A+ +++I PF P S DTSNF PE Sbjct: 740 LNRNPKHRLGA-KADAKELKEHPFFHDVDWDALSKKQVIPPFKPKLKSDTDTSNFDPE 796 >UniRef50_Q4UE84 Cluster: CAMP-dependent protein kinase catalytic subunit, putative; n=2; Theileria|Rep: CAMP-dependent protein kinase catalytic subunit, putative - Theileria annulata Length = 353 Score = 253 bits (619), Expect = 5e-66 Identities = 115/274 (41%), Positives = 173/274 (63%), Gaps = 3/274 (1%) Query: 26 VKAIGNGAYGEVFL---VRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPF 82 +K +G G +G+VFL V + F A+K ++K ++ + H+I E K+L + PF Sbjct: 49 IKVLGQGGFGKVFLAQKVEENSEFELCAVKRLQKHPLIVQKQVDHIISENKLLASVNHPF 108 Query: 83 VVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEV 142 +V ++KDN YLY ++ Y++ G+ FTY++K FYA+QV EYLH + Sbjct: 109 IVKHLGSYKDNHYLYLVMEYVSSGDFFTYLRKENYLESHDAMFYAAQVTAMFEYLHDNNI 168 Query: 143 VHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSVDWW 202 ++RD+KPEN+L+ +GYLKL DFGF KV++ +T+TLCGTPEY++PE+I GY +VDWW Sbjct: 169 IYRDLKPENLLLCFDGYLKLTDFGFAKVVEFRTYTLCGTPEYMSPEIILHLGYGKAVDWW 228 Query: 203 ALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRIG 262 LG L +EM AG+PPF+ S+P LY+K+L K P + + K L LL +PS+R G Sbjct: 229 TLGILIYEMLAGYPPFYDSNPQSLYDKILKCKLKFPIHYDEDAKYLTSRLLVTEPSQRFG 288 Query: 263 SLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 +L GI +IK WF +D+ A+ ++L P +P Sbjct: 289 NLHKGIDDIKKCKWFESMDFDALVEKELSPPHIP 322 >UniRef50_Q9HGS0 Cluster: CAMP-dependent protein kinase catalytic subunit; n=3; Sclerotiniaceae|Rep: CAMP-dependent protein kinase catalytic subunit - Botrytis cinerea (Noble rot fungus) (Botryotinia fuckeliana) Length = 917 Score = 253 bits (619), Expect = 5e-66 Identities = 128/298 (42%), Positives = 187/298 (62%), Gaps = 10/298 (3%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL---QC 77 DDF I+K IG G +G+V+ VR K T +AMKV++K V+V++ H + E+ IL Sbjct: 512 DDFQILKLIGKGTFGQVYQVRKKDTKRIYAMKVLQKKVIVQKKEVAHTVGERNILVRTAT 571 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 PF+V L +F+ LY + Y++GGE+F ++QK G F + KFY +++ILALE+L Sbjct: 572 ADSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFDEQRAKFYIAELILALEHL 631 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSK- 193 H ++V+RD+KPENIL+D+NG++ LCDFG K K T T CGT EYLAPEV+ + Sbjct: 632 HKHDIVYRDLKPENILLDANGHIALCDFGLSKANLTKNATTNTFCGTTEYLAPEVLLDEA 691 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCP-ENMSPECKNLLKGL 252 GY+ VD+W+LG L FEM G PF+A D ++Y+ + G + P + ++ E +N +KGL Sbjct: 692 GYTKMVDFWSLGVLVFEMCCGWSPFYAEDTQQMYKNIAFGKVRFPRDTLTTEGRNFVKGL 751 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309 L +P R+G+ E+K H +F +DW A+ + + PF P S DTSNF PE Sbjct: 752 LNRNPKHRLGATDDA-EELKRHPFFQDIDWHALTQKLITPPFKPKLKSETDTSNFDPE 808 >UniRef50_Q6C936 Cluster: Yarrowia lipolytica chromosome D of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome D of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 683 Score = 253 bits (619), Expect = 5e-66 Identities = 127/301 (42%), Positives = 193/301 (64%), Gaps = 10/301 (3%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL---QC 77 +DF+I++ IG G +G+V+ VR K T +AMKV+ K VVV++ H I E+ IL Sbjct: 308 EDFEILRLIGKGTFGQVYQVRKKDTRRIYAMKVLSKKVVVQKKEIAHTIGERDILVRTST 367 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 Q PF+V L +F+ LYF+ Y++GGE+F ++Q+ G FS+ KFY +++++ALE+L Sbjct: 368 TQSPFIVGLKFSFQTEADLYFVTDYMSGGELFWHLQREGRFSEQRAKFYIAELVIALEHL 427 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSK- 193 H +V+RD+KPENIL+D+NG++ LCDFG K + T T CGT EYLAPEV+ + Sbjct: 428 HDNNIVYRDLKPENILLDANGHIALCDFGLSKANVTQGDTTSTFCGTTEYLAPEVLLDES 487 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-MSPECKNLLKGL 252 GY+ VD+W+LG L FEM G PF A D ++Y+ + G K P++ +S E ++ +KGL Sbjct: 488 GYTKMVDFWSLGVLIFEMCCGWSPFHADDTQQMYKNIAFGKVKFPKDALSAEGRSFVKGL 547 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIP 311 L +P R+G+ + E++ H +F+ +DW + +K+ PF P +S DTSNF PE Sbjct: 548 LNRNPENRLGA-QDDARELRRHPFFHDIDWDQLIQKKIPPPFKPHVASETDTSNFDPEFT 606 Query: 312 Q 312 + Sbjct: 607 E 607 >UniRef50_Q39030 Cluster: Serine/threonine-protein kinase AtPK19; n=19; Magnoliophyta|Rep: Serine/threonine-protein kinase AtPK19 - Arabidopsis thaliana (Mouse-ear cress) Length = 471 Score = 252 bits (617), Expect = 9e-66 Identities = 114/290 (39%), Positives = 183/290 (63%), Gaps = 3/290 (1%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 ++DF+++K +G GA+G+V+ VR K T +AMKV+ K +VE+NHA+++ E+ IL I Sbjct: 137 IEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKID 196 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+V L +F+ LY +L +I GG +F + G+F + L + Y ++++ A+ +LH Sbjct: 197 HPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHE 256 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTW--TLCGTPEYLAPEVITSKGYSF 197 ++HRD+KPENIL+D +G++ L DFG K ++ T ++CGT EY+APE++ KG+ Sbjct: 257 KGIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDK 316 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 + DWW++G L +EM G PPF S K+ +K++ K P+ +S E LLKGLLQ +P Sbjct: 317 AADWWSVGILLYEMLTGKPPFLGS-KGKIQQKIVKDKIKLPQFLSNEAHALLKGLLQKEP 375 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +R+GS G EIK H WF ++W+ + +++ F P S +NF Sbjct: 376 ERRLGSGPSGAEEIKKHKWFKAINWKKLEAREVQPSFKPAVSGRQCIANF 425 >UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1; Chlamydomonas reinhardtii|Rep: CGMP-dependent protein kinase - Chlamydomonas reinhardtii Length = 1027 Score = 250 bits (613), Expect = 3e-65 Identities = 126/291 (43%), Positives = 185/291 (63%), Gaps = 5/291 (1%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ-CIQF 80 + + + IG G +G V +VR+ T +A+KV+ K+ +VE +H+I E+KIL+ Sbjct: 702 ELEFHRIIGTGQFGLVRVVRNIKTNEVYALKVMHKAPIVESKQIEHVINERKILEEACTH 761 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF V L A++D LY + ++ GGE+F ++ G F + FYA+ V+LALE+LH Sbjct: 762 PFCVRLCGAYQDKASLYLLQEWVPGGELFHHLDVEGAFDEPTAMFYAANVLLALEFLHAK 821 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVL-KKKTWTLCGTPEYLAPEVITSKGYSFSV 199 +V+RD+KPEN+L+D+ GY+K+ DFGF K + KT+T+CGTP+Y APEVI +G + + Sbjct: 822 GIVYRDLKPENLLLDTQGYIKMADFGFAKYIGGDKTYTICGTPDYQAPEVIMRRGTTKAA 881 Query: 200 DWWALGDLSFEMEAGHPPF--FASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 D+WALG L FEM G PPF DP + + L G + P +S + +L+ LLQV+P Sbjct: 882 DYWALGVLIFEMLVGDPPFKSLTGDPWDTFRRTLSGRFYVPNFISDQAADLIFKLLQVNP 941 Query: 258 SKRIGSLKG-GIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 KR+GS K G EIK H WF+ +DW+A+ +KL +PF P +P DTSNF Sbjct: 942 DKRLGSDKRLGAEEIKRHRWFSRIDWRALEQKKLPSPFRPRVRNPLDTSNF 992 >UniRef50_A0CDF0 Cluster: Chromosome undetermined scaffold_17, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_17, whole genome shotgun sequence - Paramecium tetraurelia Length = 416 Score = 249 bits (609), Expect = 9e-65 Identities = 122/315 (38%), Positives = 197/315 (62%), Gaps = 11/315 (3%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 DF K +G G++G+V LV K T +AMK++ K ++ +RN H E+ IL+ ++ P Sbjct: 74 DFQFEKVLGRGSFGKVMLVTHKETNKLYAMKILRKEMIEKRNQRLHTQNERAILENVKNP 133 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F+V L AF+ LY I+ ++ GGE+F ++++ F + KFY++++ILA+EYLH + Sbjct: 134 FIVQLHYAFQTRTKLYLIMDFLIGGELFFHLRRAFRFQEERAKFYSAELILAIEYLHQRD 193 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKV-LK--KKTWTLCGTPEYLAPEVITSKGYSFS 198 +++RD+KPENIL+D G+LK+ DFG K+ LK +KT T CGTPEYLAPE++ G++ Sbjct: 194 IIYRDLKPENILLDMEGHLKITDFGLSKINLKDDEKTNTFCGTPEYLAPEILLGGGHNKC 253 Query: 199 VDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPS 258 VDWW+LG L +EM AG PPF++ D ++++ L + + S +++L GLLQ DP+ Sbjct: 254 VDWWSLGALLYEMLAGAPPFYSKDKTQMFKNRLEKPIEMKDWFSSAARSILNGLLQNDPT 313 Query: 259 KRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEI-----PQ- 312 KR+G G EI+ H +F +DW ++++++ PF P D +F ++ PQ Sbjct: 314 KRLG--VNGSQEIRDHEFFREIDWDRLYNKQIQPPFKPKVFGHKDLRHFDDMFTKEPPQD 371 Query: 313 PKLRKVSKYLYEEEF 327 + K+ K+ E+F Sbjct: 372 TPINKLQKFETYEQF 386 >UniRef50_Q4XNV1 Cluster: Rac-beta serine/threonine protein kinase, putative; n=1; Plasmodium chabaudi|Rep: Rac-beta serine/threonine protein kinase, putative - Plasmodium chabaudi Length = 698 Score = 248 bits (608), Expect = 1e-64 Identities = 113/290 (38%), Positives = 176/290 (60%), Gaps = 3/290 (1%) Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPF 82 F+ +K IG G+YG+V LV+ + +AMK++ K ++ +N +H +EK IL+ + PF Sbjct: 372 FNFLKVIGKGSYGKVLLVKHVQSNKLYAMKILRKENIISKNQLEHTKVEKNILKSVSHPF 431 Query: 83 VVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEV 142 +V + AF+ + LYFIL Y GGE+F ++ K F++ + +FY S++I+ L+YLH + Sbjct: 432 IVKMYYAFQTSKKLYFILEYCPGGELFFHLSKLNKFTEEIARFYISEIIITLQYLHKLSI 491 Query: 143 VHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYSFSV 199 ++RD+KPEN+L+D G+++L DFG K +LCGTPEYL+PE+I G+ S Sbjct: 492 IYRDLKPENVLLDKYGHIRLTDFGLSKKCISDNNSAKSLCGTPEYLSPEIIQQTGHGKSA 551 Query: 200 DWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSK 259 DWW+LG + +EM G PF + L+E + K P +SPE +LLK LLQ +P K Sbjct: 552 DWWSLGIMLYEMVTGELPFSGESRDVLFENIKYKKIKIPNKLSPEVGDLLKKLLQKNPRK 611 Query: 260 RIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 R+GS EIK H +F ++W + +K+ PF P+ + D NF + Sbjct: 612 RLGSGITDAEEIKKHPFFKNINWDDVCSKKISPPFKPVLINTIDLRNFDD 661 >UniRef50_Q54IF2 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 641 Score = 247 bits (604), Expect = 4e-64 Identities = 121/314 (38%), Positives = 189/314 (60%), Gaps = 3/314 (0%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 TVDDF ++ IG GA+G+V LV+ T +AMKV++K + N H E+K+L+ Sbjct: 169 TVDDFIFLRMIGRGAFGQVNLVKKIDTGRLYAMKVIKKDKCLNMNAVGHTFTERKLLKKY 228 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L +F+ L +L YI GGE+F +I + FS+ +FY Q++LA+ +LH Sbjct: 229 YHPFIVGLKYSFQTQDSLCMVLDYIGGGELFYHISERETFSEETARFYIGQIMLAIGFLH 288 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGY 195 V++RD+K EN+L+D +G + L D G CK ++ T+T+CG+PEY+APE+I GY Sbjct: 289 EHGVIYRDLKLENLLMDLDGNICLVDLGLCKEGIQEGHVTYTMCGSPEYVAPEIINGTGY 348 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 S SVDWWALG L +EM AG PPF++ DP+++ + +L K P +S +L+ LL Sbjct: 349 SKSVDWWALGTLFYEMIAGLPPFYSEDPHEMTKLILSSPLKFPPQISKNAASLVSLLLNR 408 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPKL 315 DPSKR+GS + + EIK+H +F ++W + ++++ PF P P D S F + Sbjct: 409 DPSKRLGSGESDVEEIKAHPFFKNVNWSKLLNKEVDPPFKPHLVGPLDLSYFDPLCTMNS 468 Query: 316 RKVSKYLYEEEFAE 329 + ++ Y ++ Sbjct: 469 QPINPYTINSNLSD 482 >UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate protein kinase, cGMP-dependent, type I; n=3; Danio rerio|Rep: Novel protein similar to vertebrate protein kinase, cGMP-dependent, type I - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 570 Score = 246 bits (603), Expect = 5e-64 Identities = 114/295 (38%), Positives = 181/295 (61%), Gaps = 2/295 (0%) Query: 29 IGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLDV 88 +G G +G+V LV Y AMK + K VV + H++LEKKILQ I+ F+V L Sbjct: 269 LGIGGFGKVELVTTLEHRKYFAMKRISKQHVVAKKQEAHILLEKKILQAIRCDFIVRLHA 328 Query: 89 AFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIK 148 AFKD+ Y+Y I+ + GGE++T +++ G F + + F + V+ A YLH +++RD+K Sbjct: 329 AFKDSRYVYMIMEFCPGGEIWTKLKEAGRFEEKIAVFITACVVEAYAYLHNKGILYRDLK 388 Query: 149 PENILIDSNGYLKLCDFGFCKVLKK--KTWTLCGTPEYLAPEVITSKGYSFSVDWWALGD 206 PEN+++DS GY+KL DFGF K L + KT++ CGTPEY++PE+I ++G+ + D+W+LG Sbjct: 389 PENLMLDSKGYVKLVDFGFAKELSRGEKTYSFCGTPEYISPEIIQNQGHDIAADFWSLGV 448 Query: 207 LSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKG 266 L +E+ G PPF +S+P K+Y K+L G P M K+++ L ++ P +R+G+ K Sbjct: 449 LIYELLVGSPPFSSSEPQKIYAKILDGVLNFPSYMGEGAKSIISKLCRLRPGQRLGNTKN 508 Query: 267 GIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPKLRKVSKY 321 GI +++ H WFN ++W + +L AP V + NF P K + ++ Sbjct: 509 GIKDVRHHRWFNSINWHKLRMGQLEAPTVRLIRKGPCYINFDRFPYDKTQAEEEF 563 >UniRef50_Q231C9 Cluster: Protein kinase C terminal domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase C terminal domain containing protein - Tetrahymena thermophila SB210 Length = 358 Score = 246 bits (602), Expect = 6e-64 Identities = 118/318 (37%), Positives = 192/318 (60%), Gaps = 8/318 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++++F ++K IG GAY +V+LVR +A+K+++K + E +ILEK IL I Sbjct: 26 SINNFTLLKMIGEGAYAKVYLVRKLDNQKVYALKILKKKKIQELGQQHRVILEKDILANI 85 Query: 79 Q-FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 + PF++ L +F+++ L+F L + GGE+F+ + + F + +FYA+Q++LA+E+L Sbjct: 86 ESHPFIIKLHYSFQNDTKLFFALDFCPGGELFSILSRKHKFDEEQCRFYAAQIVLAIEHL 145 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTWTLCGTPEYLAPEVITSKGY 195 H +++RD+KPEN+++D GY+++ DFG K + + +++CGTPEYLAPE++ + G+ Sbjct: 146 HKHNIIYRDLKPENVILDKEGYIRISDFGLSKDNIEDQTAFSVCGTPEYLAPEILNNSGH 205 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFA-SDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 VDWWALG+L +EM G PPF+ ++ +L++K+ P S CK+LL L Sbjct: 206 GKPVDWWALGNLIYEMLTGLPPFYVENNREELFKKIKYTEITIPSYFSKACKDLLTRLFL 265 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE--IPQ 312 +P +R+GS G EIK H WF +DW + +K APFVP + D SNF + + Q Sbjct: 266 KNPYQRLGS--NGAEEIKDHPWFTDVDWDKMLQKKYNAPFVPKLKNEIDVSNFDDYFVHQ 323 Query: 313 PKLRKVSKYLYEEEFAEF 330 P EF+ F Sbjct: 324 PLNESYQDNQIYHEFSNF 341 >UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to cGMP-dependent protein kinase 21D CG3324-PA; n=2; Apocrita|Rep: PREDICTED: similar to cGMP-dependent protein kinase 21D CG3324-PA - Apis mellifera Length = 723 Score = 246 bits (601), Expect = 8e-64 Identities = 120/297 (40%), Positives = 180/297 (60%), Gaps = 4/297 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKI-TFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77 T+ D D +G G +G V LV K + A+K ++K V+VE+ +H++ EK I+Q Sbjct: 410 TLADLDTKGTLGVGGFGRVDLVTLKSDSEKSFALKKLKKKVMVEQQQQEHVLNEKHIMQA 469 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 PF+ L +KD Y+YF++ GG+++T +Q+ F D+ +F V+ AL++L Sbjct: 470 CDSPFICKLYQTYKDRKYVYFLMEVCLGGDVWTTLQRRRFFDDATAQFMVGCVVEALDHL 529 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-KKKTWTLCGTPEYLAPEVITSKGYS 196 H +V+RD+KPEN+++D GYLKL DFGF K + KTWT GTPEY+APE+I ++G+ Sbjct: 530 HSMNIVYRDLKPENLMLDIRGYLKLVDFGFSKKIGPSKTWTFAGTPEYVAPEIILNRGHD 589 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254 +VD+WALG L E+ G PPF SD +Y K++ G P ++ NL+K LL+ Sbjct: 590 RAVDYWALGILIHELLIGKPPFRGSDHMTIYNKIVKGIEVVGIPNTINKNANNLIKKLLR 649 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIP 311 ++PS+R+G + GI +I+ H WF+G +W A+ L AP VP S DT NF P Sbjct: 650 LNPSERLGYQRNGIQDIRDHKWFHGFNWNALQKLTLPAPIVPTVQSRIDTRNFERYP 706 >UniRef50_Q39908 Cluster: CAMP-dependent protein kinase; n=1; Gonyaulax polyedra|Rep: CAMP-dependent protein kinase - Gonyaulax polyedra (Dinoflagellate) Length = 332 Score = 246 bits (601), Expect = 8e-64 Identities = 115/281 (40%), Positives = 175/281 (62%), Gaps = 5/281 (1%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +DDF +VK +G G+YG+V LVR +AMK++ K V++RN +H E+ +L+ + Sbjct: 6 LDDFTLVKVLGKGSYGKVMLVRGAQDNRLYAMKMLRKENVIKRNQVEHTKTERSVLETVS 65 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+VTL AF+ LY ++ Y GGE+F ++ + G FS+ T+FY ++ A+ YLH Sbjct: 66 HPFIVTLHYAFQTPKKLYMVMEYCPGGELFFHLSRAGRFSEGRTRFYVAETSSAVAYLHQ 125 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYS 196 V++RD+KPEN+LID G+ K+ DFG K T+CGTPEYLAPE++ KG+ Sbjct: 126 LNVIYRDLKPENLLIDGEGHAKITDFGLRKEGIQDNHSAMTMCGTPEYLAPEILDKKGHG 185 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 +VDW+++G L++EM G PPF+ D KL++++ G P+ +S K L+ LLQ + Sbjct: 186 KAVDWYSVGALTYEMLTGLPPFYTKDLQKLFDRIRRGELTYPDYVSVLAKEFLRALLQRN 245 Query: 257 PSKRI-GSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 P R+ G + GG E+K H +F GLDW A+ + + PF P Sbjct: 246 PDARLAGGVPGG-DEVKGHEFFGGLDWVALEKRAIPPPFKP 285 >UniRef50_UPI000150A8F4 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 399 Score = 245 bits (600), Expect = 1e-63 Identities = 113/281 (40%), Positives = 177/281 (62%), Gaps = 4/281 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++D F ++ IG G+Y +V LVR K +A+K ++KS++ +N +H+I E+ ILQ + Sbjct: 40 SMDSFYLLSIIGKGSYAKVSLVRKKDDNQVYALKAIKKSLIEAKNQKEHIITERNILQTV 99 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 ++V + AF+D L+F+L Y GGE+++ + ++ TKFYA+Q++ A+EYLH Sbjct: 100 NNQYIVKMKYAFQDKQKLFFVLEYCGGGELYSLLSSKKYLNEQQTKFYAAQLVKAIEYLH 159 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKT--WTLCGTPEYLAPEVITSKGY 195 +++RD+KPENILID +GY+KL DFG K+ +K T +LCGTPEYLAPE++ G+ Sbjct: 160 SHNIIYRDLKPENILIDKDGYIKLTDFGLSKMDIKHNTEATSLCGTPEYLAPEILEQSGH 219 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 VDWW LG++ +EM G PPF+ + +++ + K + + KNLL LL+ Sbjct: 220 GKPVDWWTLGNIIWEMMTGLPPFYNENRKEMFHHIKELPLKNHPRIQGDLKNLLHSLLEK 279 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 DP+KR+G++ G EI H WF L W + +K+ PFVP Sbjct: 280 DPNKRLGTIDGA-KEIIDHPWFKDLRWDQLEQRKINPPFVP 319 >UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23; Euteleostomi|Rep: cGMP-dependent protein kinase 2 - Homo sapiens (Human) Length = 762 Score = 245 bits (600), Expect = 1e-63 Identities = 118/297 (39%), Positives = 182/297 (61%), Gaps = 4/297 (1%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 + +I+ +G G +G V LV+ K AMK + K +V+ +H+ EK+IL+ + P Sbjct: 452 NLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSP 511 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F+V L FKDN Y+Y +L GGE+++ ++ G F + +KF + V A +YLH Sbjct: 512 FIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLG 571 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYSFSV 199 +++RD+KPEN+++D+ GYLKL DFGF K + +KTWT CGTPEY+APEVI +KG+ FSV Sbjct: 572 IIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSV 631 Query: 200 DWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC--PENMSPECKNLLKGLLQVDP 257 D+W+LG L +E+ G+PPF D Y +L G K P ++ ++L++ L + +P Sbjct: 632 DFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNP 691 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPK 314 ++R+G+LK GI +IK H W NG +W+ + + L +P P D S F + P K Sbjct: 692 TERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEK 748 >UniRef50_UPI00006CFFA7 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 535 Score = 245 bits (599), Expect = 1e-63 Identities = 111/296 (37%), Positives = 190/296 (64%), Gaps = 6/296 (2%) Query: 17 DKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ 76 D ++DF ++K +G GA+G+V LV DK T + AMKV++K V+++ +H EK IL+ Sbjct: 210 DVCLEDFQLLKVLGGGAFGKVLLVEDKQTQEWFAMKVIKKQVIIQNGKFEHTKTEKAILE 269 Query: 77 CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + FPF+V L AF+DN +++F++ ++ GGE++ Y+++ G F++S TKFY +Q+ILAL + Sbjct: 270 HVNFPFLVNLVYAFQDNQHIFFVMQFLKGGELYQYLKRDGRFTESRTKFYIAQLILALGH 329 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSK 193 LH +++RD+K ENI++DS GY+ L DFG K + ++ T CGT EYL+PE++ Sbjct: 330 LHSKNIIYRDLKLENIVMDSTGYICLTDFGLAKKIIHQQQIATTFCGTAEYLSPEILKGD 389 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKG 251 G F+ DWWALG + +E+ G+ PF + ++++E++ +K +S E K+ ++ Sbjct: 390 GQDFTADWWALGIICYELLYGNTPFHNKNAHQMFEQIKYAKLEFKNTVAISNEAKDFIEK 449 Query: 252 LLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 L D +KR+G++ G ++++H WFN +D+ + ++ FVP+ SNF Sbjct: 450 CLTKDKTKRLGAINGQ-SDVQAHPWFNDIDFNKLLKKEYSPEFVPVTEGMSWISNF 504 >UniRef50_Q240P0 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 796 Score = 244 bits (598), Expect = 2e-63 Identities = 114/290 (39%), Positives = 183/290 (63%), Gaps = 6/290 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++ DF + K +G G++G+V LV + +AMKV+ K + +H + E++IL+ I Sbjct: 76 SISDFRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKKSIKNERQKRHTLTERQILEKI 135 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L AF+ N LY +L ++ GGE+F +++K G FS+ +T+FYASQ+++ LE+LH Sbjct: 136 DHPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGKFSEEVTRFYASQIVIGLEHLH 195 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSK-GYSF 197 ++++RD+KPENIL+DS G LKL DF +LCGTPEYLAPE+ITSK G+ Sbjct: 196 QHKIIYRDLKPENILLDSEGNLKLADFE-----NAPAHSLCGTPEYLAPEIITSKVGHDK 250 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 +VDWW+ G L +EM G PPF++++ ++ ++ P+N+S K+LL+ LL V+P Sbjct: 251 TVDWWSFGALVYEMLTGSPPFYSNNKKQMLHNIIYKPIPIPKNLSDTAKSLLQQLLVVNP 310 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 R+G G ++K+H +F ++W+A+ +K+ P + DT F Sbjct: 311 KNRLGYGDNGTSDVKNHPFFATINWEAMKERKIKTPLNINVTDERDTKYF 360 >UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=1; Hydra oligactis|Rep: Cyclic GMP-dependent protein kinase - Hydra oligactis (Hydra) Length = 742 Score = 244 bits (597), Expect = 2e-63 Identities = 118/312 (37%), Positives = 187/312 (59%), Gaps = 6/312 (1%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 DF V +G G +G V LV+DK A+K + K VVE +H+ EKKIL + Sbjct: 431 DFKPVATLGVGGFGRVELVQDKRNKDRTFALKSLSKHYVVETKQQEHVFNEKKILMSLDS 490 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF++ L +FKD+ Y+Y +L GGE++T ++ F ++ +FY + V+ A EY+H Sbjct: 491 PFIIKLYKSFKDDRYVYLLLEVCLGGELWTILRDRDYFEEAACRFYIACVVEAFEYIHKR 550 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK--KTWTLCGTPEYLAPEVITSKGYSFS 198 +++RD+KPEN+L+DS GY+K+ DFGF K + KTWT CGTPEY+ PE+I +KG+ S Sbjct: 551 GIIYRDLKPENLLMDSQGYIKIVDFGFAKKISSGTKTWTFCGTPEYVPPEIILNKGHDSS 610 Query: 199 VDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQVD 256 D+W+LG L +E+ G+PPF +SDP Y +L G + ++ +NL+K L + + Sbjct: 611 ADYWSLGILIYELMVGNPPFSSSDPMSTYNIILRGIEVLEFSNLVTKNAQNLIKRLCKEN 670 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPKLR 316 P +R+G+ K G+ +I+ H W+ G W + ++ L AP +P + D SNF K + Sbjct: 671 PMERLGNQKDGVEDIRKHKWYQGFHWSGLRNRTLQAPIIPKIRNITDNSNFDYFSPLKEK 730 Query: 317 KVSKYL-YEEEF 327 ++ ++E+F Sbjct: 731 PQKEFSGWDEDF 742 >UniRef50_Q2U061 Cluster: Ribosomal protein S6 kinase and related proteins; n=20; Pezizomycotina|Rep: Ribosomal protein S6 kinase and related proteins - Aspergillus oryzae Length = 681 Score = 244 bits (597), Expect = 2e-63 Identities = 116/293 (39%), Positives = 180/293 (61%), Gaps = 7/293 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 ++DF+++K +G G++G+V V K T +A+K + K+ ++ R+ H + E+ +L I Sbjct: 335 LEDFELLKVVGKGSFGKVMQVMKKDTGRIYALKTIRKAHIISRSEVTHTLAERSVLAQIN 394 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+V L +F+ LYF+L ++ GGE+F ++Q+ F + +FY ++++ ALE LH Sbjct: 395 NPFIVPLKFSFQSPEKLYFVLAFVNGGELFHHLQREQRFDINRARFYTAELLCALECLHG 454 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK---KTWTLCGTPEYLAPEVITSKGYS 196 +V++RD+KPENIL+D G++ LCDFG CK+ K +T T CGTPEYLAPE++ GY+ Sbjct: 455 FKVIYRDLKPENILLDYTGHIALCDFGLCKLDMKDEDRTNTFCGTPEYLAPELLLGNGYT 514 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--MSPECKNLLKGLLQ 254 SVDWW LG L +EM G PPF+ + N +Y K+L P + ++LL LL Sbjct: 515 KSVDWWTLGVLLYEMLTGLPPFYDENTNDMYRKILQEPLTFPSTDIVPAAARDLLTRLLD 574 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 DP +R+G+ G EIKSH +F +DW+ + +K F P DT+NF Sbjct: 575 RDPQRRLGA--NGAAEIKSHHFFANIDWRKLLQRKYEPSFRPNVVDARDTANF 625 >UniRef50_A5DV85 Cluster: Serine/threonine-protein kinase SCH9; n=9; Saccharomycetales|Rep: Serine/threonine-protein kinase SCH9 - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 844 Score = 244 bits (596), Expect = 3e-63 Identities = 123/311 (39%), Positives = 191/311 (61%), Gaps = 10/311 (3%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL---QC 77 DDF+ ++ +G G +G+VF V+ K T +AMK++ K V+V++ H I E+ IL Sbjct: 425 DDFEFLRLLGKGTFGQVFQVKKKDTSRIYAMKILSKKVIVKKKEIAHTIGERNILVRTSA 484 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 PF+V L +F+ L+ + Y++GGE+F ++QK G FS+ KFY +++ILALE+L Sbjct: 485 AASPFIVGLKFSFQTPTDLFLVTDYMSGGELFWHLQKDGRFSEERAKFYIAELILALEHL 544 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSK- 193 H ++V+RD+KPENIL+D+NG++ LCDFG K T T CGT EYLAPE++ + Sbjct: 545 HDNDIVYRDLKPENILLDANGHIALCDFGLSKANLNNDGTTNTFCGTTEYLAPEILLDES 604 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCP-ENMSPECKNLLKGL 252 GY+ VD+W+LG L FEM G PF+A + ++Y+ + G + P E +SPE ++ +KGL Sbjct: 605 GYTKMVDFWSLGVLIFEMCCGWSPFYADNTQQMYKNIAFGKVRFPKEVLSPEGRSFVKGL 664 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIP 311 L +P R+G+ E+++H +F +DW + + + PF P +S DTSNF PE Sbjct: 665 LNRNPRHRLGATNDA-RELRAHPFFADIDWDLLRSKSIPPPFKPHLASETDTSNFDPEFT 723 Query: 312 QPKLRKVSKYL 322 + K + Sbjct: 724 SESTSVLKKQM 734 >UniRef50_UPI00006CB772 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 339 Score = 243 bits (595), Expect = 4e-63 Identities = 111/282 (39%), Positives = 176/282 (62%), Gaps = 6/282 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+DDFD+ +G G++ +V LV+ K T +AMK+++K + R +++++E+ +L + Sbjct: 7 TIDDFDLKYVLGKGSFAKVVLVKKKDTKKLYAMKILKKDYIQRRRQDQNVMVERNLLVEM 66 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF++ + F+ LYF L Y GGE+F + K F++ T+FY SQ+ILA+E+LH Sbjct: 67 NHPFIIKVKHTFQSEKKLYFCLEYCPGGELFNLLYKKERFNEDQTRFYVSQMILAIEFLH 126 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTW---TLCGTPEYLAPEVITSKGY 195 V++RD+KPEN+LID GY+++ DFG K K + ++ GTPEYLAPE++ KGY Sbjct: 127 EKNVIYRDLKPENVLIDKQGYIRVTDFGLSKQNVKGNYEAKSVVGTPEYLAPEILEGKGY 186 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNK-LYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 +VDWW LG + +E+ G PPF+ + + L++++ + +N +CK+L+ LLQ Sbjct: 187 GKTVDWWTLGCIIYELLTGRPPFYKDEGKEDLFQQIQQNKVEIEKNWISDCKDLVLSLLQ 246 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 DP R+G G +EIK H WF LDW + ++K PFVP Sbjct: 247 KDPKLRLGF--NGAHEIKDHPWFMSLDWDVLKNKKYTPPFVP 286 >UniRef50_Q9NAH6 Cluster: Putative uncharacterized protein rsks-1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein rsks-1 - Caenorhabditis elegans Length = 580 Score = 243 bits (595), Expect = 4e-63 Identities = 120/295 (40%), Positives = 187/295 (63%), Gaps = 9/295 (3%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYH----AMKVVEKSVVVE-RNHAKHLILEKKIL 75 +DF ++K +G G YG+VF VR K T + + AMKV++K+ +V + H E+ IL Sbjct: 81 EDFQLLKVLGKGGYGKVFQVR-KTTGSDNGQIFAMKVLQKATIVRNQKDTAHTKAERNIL 139 Query: 76 QCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135 + ++ PF+ L AF+ LY IL Y++GGE+F ++++ G+F +++ KFY S+++++LE Sbjct: 140 EAVKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYLSEIVVSLE 199 Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITS 192 +LH +++RD+KPENIL+D+ G++KL DFG CK +KT T CGT EY+APE++ Sbjct: 200 HLHQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQKTHTFCGTIEYMAPEILMR 259 Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252 G+ +VDWW+LG L F+M G PPF A + K +K+L G P +S E ++L+K L Sbjct: 260 CGHGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLPAYLSNEARDLIKKL 319 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 L+ R+G+ EIKSH +F DW ++ ++L APF P + DTS F Sbjct: 320 LKRHVDTRLGAGLSDAEEIKSHAFFKTTDWNLVYARQLEAPFKPNIENDEDTSLF 374 >UniRef50_A0E058 Cluster: Chromosome undetermined scaffold_71, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_71, whole genome shotgun sequence - Paramecium tetraurelia Length = 562 Score = 243 bits (595), Expect = 4e-63 Identities = 113/295 (38%), Positives = 183/295 (62%), Gaps = 5/295 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 +++DFD++K +G GA+G+V + K T A+K + K ++++N +H E+K+L+ I Sbjct: 230 SIEDFDLIKVLGRGAFGKVMMCEKKETKELFAIKSLRKEHIMDKNQLEHTRAERKLLEEI 289 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+++L+ AF+ L+F++ ++ GGE+F +++ F +S +FYA+ ++LALEYLH Sbjct: 290 DNPFLISLEYAFQTQEKLFFVMRFMRGGELFKHLRDKRRFPESTAQFYAASILLALEYLH 349 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK--TWTLCGTPEYLAPEVITSKGYS 196 +VV+RD+KPENIL+D GY+K+ D+G K LK T++ GTPEYLAPE+I G+ Sbjct: 350 KMQVVYRDLKPENILMDEFGYIKMTDYGLAKFLKPGDFTYSFVGTPEYLAPEIIRQNGHG 409 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPE--NMSPECKNLLKGLLQ 254 VDWW+ G L +EM G PPFF+ + ++L++ ++ P +S + K+L+ LL Sbjct: 410 LGVDWWSFGILIYEMVVGRPPFFSQNQSQLFKSIVESDVVFPSQLTLSIQIKDLITQLLT 469 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 +P +R+G G IK H WF +Q + +KL AP VP D NF + Sbjct: 470 KNPFERLGH-NGDAQSIKEHPWFRDYPFQDLIDKKLQAPIVPKLYDKLDVQNFDQ 523 >UniRef50_A5K8X1 Cluster: Rac-beta serine/threonine protein kinase, putative; n=4; Alveolata|Rep: Rac-beta serine/threonine protein kinase, putative - Plasmodium vivax Length = 755 Score = 242 bits (592), Expect = 1e-62 Identities = 113/290 (38%), Positives = 176/290 (60%), Gaps = 3/290 (1%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 D+F +K IG G+YG+V LV+ +AMK++ K ++ RN +H +E+ +L+C+ Sbjct: 427 DNFTFLKVIGRGSYGKVLLVKHTQNNKLYAMKILRKENIISRNQLEHTKIERNVLKCVSH 486 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF+V L AF+ LYFIL Y GGE+F ++ K ++ FY +++ILAL+YLH Sbjct: 487 PFIVKLYYAFQTTKKLYFILEYCPGGELFFHLSKMRELTEEAAIFYTAEIILALQYLHKL 546 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197 +++RD+KPEN+L+D G+++L DFG K +LCGTPEYLAPE+I G+ Sbjct: 547 NIIYRDVKPENVLLDEMGHIRLTDFGLSKEGISDNNSARSLCGTPEYLAPEIIDQCGHGK 606 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 +VDWW+LG + +EM G PF +S L+E++ + + P +SP+ +LLK L + +P Sbjct: 607 AVDWWSLGIMLYEMLTGRLPFNSSSRAVLFERIKHETLRYPCFLSPDAVDLLKKLFEKNP 666 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 KR+GS EIK+H +F ++W + ++K+ PF P D NF Sbjct: 667 KKRLGSGVTDAEEIKNHPFFKNVNWDDVLNKKVKPPFKPPLFDQMDVQNF 716 >UniRef50_A0CFD9 Cluster: Chromosome undetermined scaffold_175, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_175, whole genome shotgun sequence - Paramecium tetraurelia Length = 383 Score = 241 bits (591), Expect = 1e-62 Identities = 119/318 (37%), Positives = 196/318 (61%), Gaps = 11/318 (3%) Query: 4 EDFNKKYSDAPI---YDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVV 60 +D KK D + ++ T +D +K +G G++G+V+LV KI +AMK ++K +++ Sbjct: 47 DDVKKKLGDFEVQNTFNITQNDVWPIKLLGRGSFGKVYLV--KIKDKLYAMKQIKKKLIL 104 Query: 61 ERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSD 120 ++ ++L+ E+ ILQ PF++ + F++ L++ ++ ++ GGE+F ++ K F Sbjct: 105 KKQQLENLLYERFILQKYDHPFIIKMYFVFQEPLFINMVMEFVQGGELFYHLNKRKKFDQ 164 Query: 121 SLTKFYASQVILALEYLHYC-EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLC 179 T FYASQ++LALE+LH V +RD+KPEN+L+ +GY+KL D G K + ++ C Sbjct: 165 KTTAFYASQLVLALEFLHETVRVAYRDLKPENVLLCRDGYIKLADMGLAKDNSELNYSFC 224 Query: 180 GTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPE 239 GT EYLAPE+I KG++ SVD+W LG + FEM GHPPF + LY K+ G +K P Sbjct: 225 GTAEYLAPEMIEEKGHNASVDFWTLGCIIFEMLFGHPPFQDENKKNLYIKIQTGEFKFPP 284 Query: 240 NMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299 S ++L+KGLLQ P +R+ S K +IK H +F +D+ I+ +KL PF P+ + Sbjct: 285 TASSSAQSLIKGLLQYHPEERL-SFK----QIKQHEFFQDIDFDLIYQKKLKPPFEPLLT 339 Query: 300 SPGDTSNFPEIPQPKLRK 317 + DT NF + + ++++ Sbjct: 340 TEKDTRNFDYVLESQMKQ 357 >UniRef50_Q96BR1 Cluster: Serine/threonine-protein kinase Sgk3; n=68; Gnathostomata|Rep: Serine/threonine-protein kinase Sgk3 - Homo sapiens (Human) Length = 496 Score = 241 bits (590), Expect = 2e-62 Identities = 114/290 (39%), Positives = 180/290 (62%), Gaps = 5/290 (1%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80 DFD +K IG G++G+V L + K+ ++A+KV++K +V+ R KH++ E+ +L + ++ Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF+V L +F+ LYF+L ++ GGE+F ++Q+ F + +FYA+++ AL YLH Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197 ++V+RD+KPENIL+DS G++ L DFG CK + T T CGTPEYLAPEVI + Y Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 340 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 +VDWW LG + +EM G PPF+ D ++Y+ +L +S ++L+ LL+ D Sbjct: 341 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDR 400 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 R+G+ K EI++H +F L W + +K+ PF P + P D NF Sbjct: 401 QNRLGA-KEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNF 449 >UniRef50_A0BY36 Cluster: Chromosome undetermined scaffold_136, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_136, whole genome shotgun sequence - Paramecium tetraurelia Length = 378 Score = 240 bits (587), Expect = 4e-62 Identities = 112/292 (38%), Positives = 182/292 (62%), Gaps = 5/292 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++ DF+ +K +G G YG+V LV K +AMK++ K ++ + N ++ E+ IL + Sbjct: 44 SLKDFEFLKVLGRGGYGKVVLVNHKSQSKLYAMKILRKDLIQQMNSRIYMETERNILALV 103 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 + PF+V L AF+ LYF++ ++ GGE+F ++++ G +S KFY +++ILALEYLH Sbjct: 104 KCPFIVNLYYAFQTKQKLYFVIDFMIGGELFYHLKRIGKMEESWAKFYCAEIILALEYLH 163 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGY 195 +++RD+KPENIL+D +G++K+ DFG CKV K+ T T+CGT +Y+APE+ KG+ Sbjct: 164 SQNIIYRDLKPENILLDQDGHVKITDFGLCKVDIKEGDFTTTICGTYDYMAPEIYLKKGH 223 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 + S DW++LG L + M G PPF++ + ++ L + +S E +L+K LL+ Sbjct: 224 NQSADWYSLGILLYVMLQGIPPFYSQNKRQMIRSRLERQIEIKTPISEEASDLIKQLLKN 283 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +P R+GS G E+KSH +FNG++W + +K+ PF P D NF Sbjct: 284 NPKDRLGS--DGSNEVKSHPFFNGVNWNDVMDKKVAPPFKPKLFGDRDLRNF 333 >UniRef50_Q33DX3 Cluster: Putative cyclic AMP-dependent protein kinase catalytic subunit; n=1; Schizophyllum commune|Rep: Putative cyclic AMP-dependent protein kinase catalytic subunit - Schizophyllum commune (Bracket fungus) Length = 427 Score = 240 bits (587), Expect = 4e-62 Identities = 113/294 (38%), Positives = 183/294 (62%), Gaps = 7/294 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 + DF I + +G G++G V LVR K ++A+KV+ K V+ +H E+ +L + Sbjct: 98 LQDFLIQRTLGTGSFGRVLLVRSKHNLRFYAIKVLNKEKVLRMKQVEHTNNERNMLHRVN 157 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 F++ L AF+D LY ++ ++ GGE+F +++ F + + KFYA++V LAL YLH Sbjct: 158 HNFIINLWGAFQDGNNLYMVMDFVPGGELFNLLRRSIRFPEPVAKFYAAEVSLALRYLHS 217 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSV 199 +++RD+KPENIL++++G++K+ DFGF K++ +TLCGTP+YLAPE+I Y+ SV Sbjct: 218 NNIIYRDLKPENILLNADGHIKVADFGFAKIVDTVAYTLCGTPDYLAPEIIWGGRYNKSV 277 Query: 200 DWWALGDLSFEMEAGHPPFFASD--PNKLYEKVLVGSYKCPENMSPECK----NLLKGLL 253 DW+ALG L +EM +G PPF D P LY K+ G P N SP +L++ L+ Sbjct: 278 DWYALGVLCYEMLSGLPPFHTPDGNPQTLYAKIREGPTSLPWN-SPNFTLYSIDLIRRLM 336 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 + +PSKR G+++ G ++ +H WF +DW+ + +++ P++P GD S F Sbjct: 337 EGEPSKRYGNMRHGAGDVFAHPWFAEVDWEKLEDREVSPPYIPNIGGAGDASAF 390 >UniRef50_A7TPV4 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 665 Score = 240 bits (587), Expect = 4e-62 Identities = 125/328 (38%), Positives = 199/328 (60%), Gaps = 9/328 (2%) Query: 9 KYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHL 68 KY + + +DF+I++ +G G +G V+ V K T T +AMKV+ K V++R KH Sbjct: 248 KYKNTDQRHYSPEDFNILRMLGKGTFGRVYQVEKKDTKTLYAMKVISKRNVIKRKEVKHT 307 Query: 69 ILEKKILQCIQ---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKF 125 + E+ IL F+V L +F+ LY + +++GGE+F ++Q+ G F + KF Sbjct: 308 LNERNILVHNANKLCSFIVKLKFSFQTAEDLYLVTDFMSGGELFLHLQREGRFPEYRAKF 367 Query: 126 YASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTLCGTPEY 184 Y +Q+++ALE+LH ++++RD+KPENIL+D+ G + LCDFG K+ L+ +T T CGT EY Sbjct: 368 YCAQLVMALEFLHDNDIIYRDLKPENILLDAKGNIALCDFGLSKLNLEGRTNTFCGTTEY 427 Query: 185 LAPE-VITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-MS 242 LAPE ++ + GY+ VD+W+LG L FEM G PFFA ++Y+K+ K P N +S Sbjct: 428 LAPELLLDATGYTKMVDFWSLGVLMFEMCCGWSPFFAPTNQQMYQKIAYSKIKFPVNSLS 487 Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302 C+ +KGL+ +P R+G++ E+++H +F DW+A+ +++ PF P SS Sbjct: 488 KGCRLFIKGLMNRNPLHRLGAINDA-RELRAHEFFRDTDWEALMKKEVTPPFKPHLSSDR 546 Query: 303 DTSNF-PEIPQ-PKLRKVSKYLYEEEFA 328 DTS F P Q P + + +Y E+ A Sbjct: 547 DTSYFDPAFTQTPTIDVIKEYNKVEDTA 574 >UniRef50_UPI000065EC1B Cluster: Homolog of Fugu rubripes "Protein kinase C, alpha type.; n=1; Takifugu rubripes|Rep: Homolog of Fugu rubripes "Protein kinase C, alpha type. - Takifugu rubripes Length = 982 Score = 239 bits (585), Expect = 7e-62 Identities = 111/305 (36%), Positives = 189/305 (61%), Gaps = 8/305 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78 +DDF + +G G +G+V L K + +A+K ++K +V R+ L+ EK+I + I Sbjct: 657 MDDFKCISVLGRGHFGKVLLAEFKRSGKLYAIKALKKGDIVSRDEVDSLVCEKRIFEVIN 716 Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + PF+V L F+ ++ F++ Y GG++ T+I IF++ +FY+S V+L LE+ Sbjct: 717 ASRHPFLVNLHGCFQTEEHVCFVMAYSPGGDLMTHIHT-SIFTEKQARFYSSCVLLGLEF 775 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK---KKTWTLCGTPEYLAPEVITSK 193 LH ++++RD+K +N+L+D++G++++ DFG CK +T T CGTPE+LAPEV+T Sbjct: 776 LHQNKIIYRDLKLDNLLMDADGFVRIADFGLCKEGMGHGDRTSTFCGTPEFLAPEVLTES 835 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y+ SVDWW LG L +EM G PF D ++++ ++ +CP +SP+ +L++ LL Sbjct: 836 NYTRSVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDDVRCPRFLSPQSASLIQQLL 895 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQP 313 Q +P R+G+ + ++KSH +F DW A+ +++ PF+P+ SP D SNF ++ Sbjct: 896 QKNPETRLGAGEEDALQVKSHRFFQATDWDALLAKRVKPPFLPVIRSPKDVSNF-DVEFT 954 Query: 314 KLRKV 318 +LR V Sbjct: 955 RLRPV 959 >UniRef50_Q7QUE9 Cluster: GLP_59_15138_16382; n=2; Giardia intestinalis|Rep: GLP_59_15138_16382 - Giardia lamblia ATCC 50803 Length = 414 Score = 239 bits (585), Expect = 7e-62 Identities = 116/303 (38%), Positives = 177/303 (58%), Gaps = 7/303 (2%) Query: 10 YSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLI 69 Y D P + D+F +K +G G++G V L + K +A+KV+ K V+E +H I Sbjct: 20 YIDPP--PTSPDEFTFMKVLGKGSFGTVCLAKHKANNKIYALKVLTKQHVIESREVEHAI 77 Query: 70 LEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQ 129 E+ IL + PF++ L AF+ L +L Y+ GGE+F +++K F +S K A+Q Sbjct: 78 SERSILASLNHPFLMRLYGAFQTPTRLIMVLEYVPGGELFFHLKKKVTFDESYVKLVAAQ 137 Query: 130 VILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTW---TLCGTPEYLA 186 ++LA+EYLH +V RD+KPENIL+ +NGY+K+ DFG K T T+ GT EY + Sbjct: 138 LVLAIEYLHDMNIVIRDLKPENILLQANGYIKVTDFGLSKQNLSMTLGAKTMAGTSEYFS 197 Query: 187 PEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECK 246 PE + + G+ VD WALG + +E+ G PPF++ D ++ K++ K P + K Sbjct: 198 PEQVQNCGHGKGVDMWALGTIIYELLTGSPPFYSDDKRAMFRKIIGEQPKMPSYFKDDLK 257 Query: 247 NLLKGLLQVDPSKRIGSLK--GGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304 +LLKGLL+ P R+G K GGI E+K H WFNG++W ++ ++ P+ P + D Sbjct: 258 DLLKGLLEKKPRSRLGCRKENGGIKELKGHPWFNGINWDKLYRKEYTIPYKPTITDNLDL 317 Query: 305 SNF 307 SNF Sbjct: 318 SNF 320 >UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14 SCAF15003, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 621 Score = 239 bits (584), Expect = 9e-62 Identities = 106/251 (42%), Positives = 167/251 (66%), Gaps = 2/251 (0%) Query: 48 YHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGE 107 Y+AMK V K +V + +H++ EKKIL+ IQ F+V L FKD Y+Y I+ + GGE Sbjct: 345 YYAMKRVSKKHIVAKRQEEHMLFEKKILKAIQCDFIVRLHATFKDTRYVYMIMEFCGGGE 404 Query: 108 MFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGF 167 ++T +++ G F + + F A+ V+ A YLH +++RD+KPEN+++D+ GY+KL DFGF Sbjct: 405 IWTKLKEVGRFDEPMAVFCAACVVEAFAYLHKKSIMYRDLKPENLMLDAKGYVKLVDFGF 464 Query: 168 CK--VLKKKTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNK 225 K V +KT++ GTPEY+APE+I ++G+ F+VD+W+LG L FE+ AG PPF +S+P K Sbjct: 465 AKEMVRAEKTYSFVGTPEYMAPEIIKNQGHDFAVDFWSLGILIFELLAGSPPFSSSEPQK 524 Query: 226 LYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAI 285 +Y K+L G K P +S K+++ L + P +R+G+ K GI +++ H WF+ ++W + Sbjct: 525 IYAKILDGVLKYPPYLSEASKSIISKLCRPRPGQRLGNTKNGIKDVRHHRWFSSINWHKL 584 Query: 286 FHQKLIAPFVP 296 +L AP P Sbjct: 585 RMSQLDAPTGP 595 >UniRef50_Q4PH11 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 753 Score = 239 bits (584), Expect = 9e-62 Identities = 124/317 (39%), Positives = 189/317 (59%), Gaps = 8/317 (2%) Query: 10 YSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLI 69 Y P T DF+ +K IG G +G VF VR K T +AMKV+ K + + H + Sbjct: 317 YERMPQKKLTPHDFEYLKLIGRGTFGRVFQVRKKDTKRIYAMKVLSKREIALKKEVTHTM 376 Query: 70 LEKKILQ-CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYAS 128 E+KIL+ + PF+V L +F+ LYF+ Y +GGE+F ++Q+ G F++ +FY + Sbjct: 377 GERKILEKSLDCPFLVGLKFSFQSATELYFVTDYKSGGELFWHLQREGRFTEERARFYIA 436 Query: 129 QVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYL 185 +++LALE+LH ++V+RD+KPENIL+D+ G++ LCDFG K + T T CGT EYL Sbjct: 437 ELVLALEHLHKYDIVYRDLKPENILLDATGHVALCDFGLSKPDLGAGQLTNTFCGTTEYL 496 Query: 186 APEVITSK-GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-MSP 243 APEV+ + GYS VD+W+LG L FEM G PF+A D ++Y + G K P + Sbjct: 497 APEVLLDESGYSKLVDFWSLGVLLFEMCCGWSPFYAEDTQQMYRNICFGKIKFPRGAIGD 556 Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303 + K +KGLL +P R+G+ + ++K H +F +D+ A+ ++L PF P+ S Sbjct: 557 DGKQFVKGLLNRNPRHRLGAQRDA-QDLKEHPFFKDIDFDALSKKQLTPPFKPLVESDES 615 Query: 304 TSNF-PEIPQPKLRKVS 319 +NF PE + L+ V+ Sbjct: 616 VANFDPEFTETDLKDVA 632 >UniRef50_UPI0000499868 Cluster: protein kinase; n=1; Entamoeba histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba histolytica HM-1:IMSS Length = 441 Score = 238 bits (583), Expect = 1e-61 Identities = 121/307 (39%), Positives = 189/307 (61%), Gaps = 13/307 (4%) Query: 8 KKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKH 67 K+ + PI +++DFDI+ +G GA+G+V LVR K T A+K+VEK V+E +H Sbjct: 106 KEEEEKPI---SIEDFDIITLLGKGAFGKVLLVRYKRTGEKFALKMVEKKKVIEMEELEH 162 Query: 68 LILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYA 127 + EK ILQ ++ PF+V L +F+ +L++++ Y GGE++ + + F +S T+FY Sbjct: 163 TMTEKNILQKVKHPFLVNLYYSFQSATHLHYVIDYCPGGELYYRLIQEKSFCESRTQFYI 222 Query: 128 SQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEY 184 SQVILALE LH +++RD+K EN+LI +GYL+L DFG K + T T CGTPEY Sbjct: 223 SQVILALECLHQMNIIYRDVKLENVLICEDGYLRLTDFGLSKENVSGNETTATFCGTPEY 282 Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--MS 242 L+PEV+ ++ Y+ +DWW +G +++EM G PF + + +LY+K+L P +S Sbjct: 283 LSPEVVLAEPYTNVIDWWGVGIMTYEMMHGQAPFISDNIQQLYQKILYSPVIFPTTSPVS 342 Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302 CK+ + +L+ R+ + + +IK+H W+N DW A++ +K+ APF P S G Sbjct: 343 AVCKDFITKMLEKKICDRLSTPE----KIKTHPWWNSFDWDALYQKKIPAPFKPDMSQDG 398 Query: 303 DTSNFPE 309 T NF E Sbjct: 399 KT-NFGE 404 >UniRef50_Q4N4B2 Cluster: CAMP-dependent protein kinase catalytic subunit, putative; n=2; Theileria|Rep: CAMP-dependent protein kinase catalytic subunit, putative - Theileria parva Length = 511 Score = 238 bits (583), Expect = 1e-61 Identities = 109/264 (41%), Positives = 176/264 (66%), Gaps = 4/264 (1%) Query: 50 AMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMF 109 ++K++ K+ ++E+ +H+ EK IL ++ PF+V +F+D L LYFIL ++ GGE+F Sbjct: 231 SLKILSKNKIIEKRQLEHVKNEKNILSTLKHPFIVGYLGSFQDTLNLYFILEFVPGGELF 290 Query: 110 TYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK 169 TY+++ F T+FYASQV+LAL+YLH ++V+RD+KPENIL+D GY++L DFGF K Sbjct: 291 TYLRRMHTFPPEYTRFYASQVLLALDYLHMNKLVYRDLKPENILLDIMGYIRLVDFGFAK 350 Query: 170 VLKK-KTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYE 228 L+ KT+T+CGT +YLAPE+ KG+ F D+++ G +E+ G PPF+++ P K Y+ Sbjct: 351 RLESGKTYTVCGTCDYLAPEIFLKKGHDFRADFYSFGVFLYELLTGVPPFYSNSPQKTYK 410 Query: 229 KVLVGSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQ 288 L ++ ++++K LL+VDPSKR+G+ + E+ H +F+G+D+ + + Sbjct: 411 LALNNEVAFGRKVNNVSRDIIKNLLRVDPSKRLGN---NVKEVYFHPFFDGIDFNMLLAK 467 Query: 289 KLIAPFVPICSSPGDTSNFPEIPQ 312 ++ AP VP SS D SNF + P+ Sbjct: 468 QIKAPIVPSVSSHDDVSNFIKYPE 491 >UniRef50_Q10364 Cluster: Serine/threonine-protein kinase sck2; n=1; Schizosaccharomyces pombe|Rep: Serine/threonine-protein kinase sck2 - Schizosaccharomyces pombe (Fission yeast) Length = 646 Score = 238 bits (583), Expect = 1e-61 Identities = 121/295 (41%), Positives = 180/295 (61%), Gaps = 9/295 (3%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL---QC 77 DDF +K IG G +G+V+LVR K T +AMKV+ K V+V R H + E+ IL Sbjct: 264 DDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSA 323 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 PF+V L +F+ LY + Y+AGGE+F ++QK F + KFY ++++LAL+ L Sbjct: 324 ADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQAL 383 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK- 193 H +V+RD+KPENIL+D G++ LCDFG K + T T CGT +YLAPEVI + Sbjct: 384 HKRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTRTFCGTTDYLAPEVILDEA 443 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-MSPECKNLLKGL 252 GY VD+W+LG L +EM G PF+A + +LY+ ++ G + P +S E ++L+K L Sbjct: 444 GYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGLLSVEARDLIKLL 503 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 L +P R+G+ G + E+ H +F+G+DW+ + +++ PF PI D SNF Sbjct: 504 LNRNPKHRLGA-HGDVEEVMKHPFFDGIDWKKLAAKEISPPFKPIVEGEIDVSNF 557 >UniRef50_Q26334 Cluster: Serine/threonine protein kinase; n=2; Entamoeba histolytica|Rep: Serine/threonine protein kinase - Entamoeba histolytica Length = 409 Score = 238 bits (582), Expect = 2e-61 Identities = 111/309 (35%), Positives = 187/309 (60%), Gaps = 8/309 (2%) Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62 KE++ + Y++ T DDF+++K IG G++G+V +V+ K AMK++ K +V ER Sbjct: 68 KEEYIELYNEGK-KKVTQDDFELLKVIGRGSFGKVMMVKKKDDGRIFAMKILRKDIVKER 126 Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122 H EK +L + PF+V L AF+ LY ++ ++ GGE+F +++ FS+ Sbjct: 127 KQVDHTKAEKNVLMQLHHPFIVKLYYAFQTTDKLYMVMDFVNGGELFYHLKNENCFSEER 186 Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK--KKTWTLCG 180 KFYA+++ L ++H +++RD+KPENIL+D+ G + + DFG K L ++T T CG Sbjct: 187 AKFYAAEIATVLIHIHSLGIIYRDLKPENILLDNTGNIVITDFGLSKQLAAGEETQTFCG 246 Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240 TP+YLAPE++ G+ VDWW+LG L +EM G PPF+ D + +Y+K+L P N Sbjct: 247 TPDYLAPEILKGVGHGPGVDWWSLGILIYEMIVGIPPFYDDDVSLMYQKILKSQPHFPRN 306 Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300 +S + K+++ GLL+ DP++R+G ++ WF+ +D++ + ++L P++P S Sbjct: 307 ISYDAKSVIMGLLEKDPAERLGG-----EDVIHMAWFDSIDFEKLKRKELTPPWIPPVKS 361 Query: 301 PGDTSNFPE 309 +TS E Sbjct: 362 QTETSQIDE 370 >UniRef50_A0E7B2 Cluster: Chromosome undetermined scaffold_80, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_80, whole genome shotgun sequence - Paramecium tetraurelia Length = 428 Score = 237 bits (580), Expect = 3e-61 Identities = 108/279 (38%), Positives = 175/279 (62%), Gaps = 5/279 (1%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +D F ++K +G G++G+V LV+ K Y+AMKV++K + +H E+ IL Sbjct: 100 IDSFRLLKVLGKGSFGKVMLVQYKSNSKYYAMKVLQKKNIKNERQKRHTETERIILATCS 159 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 F+V L AF+ LY ++ Y+ GGE+F +++K G F + + KFYA++++L L+YLH Sbjct: 160 SIFLVRLRYAFQSQYKLYLVVDYMPGGELFYHLRKVGRFKEEVAKFYAAEILLGLQYLHE 219 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSK-GY 195 +++RD+KPENIL+D NG++KL DFG K++ ++ ++LCGTPEYLAPE++T+K GY Sbjct: 220 NHIIYRDLKPENILLDENGHIKLTDFGLSKIMMEEDETAFSLCGTPEYLAPEILTTKTGY 279 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 + DWW+ G L +EM G PP + + ++ ++L P+ +S ++LL+ LL V Sbjct: 280 DKTCDWWSFGALLYEMLVGAPPHYKENKKEMIRRILTQPIPYPQYLSENARSLLEQLLVV 339 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPF 294 DP KR+G G Y+I H +F G+D I ++ P+ Sbjct: 340 DPKKRLGYENDG-YDIMKHDFFAGIDLAEIIQHRIQPPY 377 >UniRef50_A0DUX2 Cluster: Chromosome undetermined scaffold_65, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_65, whole genome shotgun sequence - Paramecium tetraurelia Length = 371 Score = 237 bits (580), Expect = 3e-61 Identities = 113/315 (35%), Positives = 191/315 (60%), Gaps = 6/315 (1%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +DDF+++K IG G++G+V LV+ + A+K++ K ++ ++ I E+KI+ I Sbjct: 53 LDDFELIKVIGRGSFGKVLLVKKRDDQQLFAVKILRKKMLSKKKQQDQAIKERKIMSLIN 112 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+V L AF+ + LY ++ ++ GGE+F +++K F + +FYA+++++A++ LH Sbjct: 113 SPFMVKLHYAFQSHSRLYMVMDFMQGGELFLHLRKRFKFPEDWVQFYAAELLVAIDLLHQ 172 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGYS 196 +++RD+KPENIL+D NG++ L DFG K+ +K T++ CGTPEY+APE++ +G++ Sbjct: 173 SNIIYRDLKPENILLDKNGHIVLTDFGLSKLGFEKNEMTYSFCGTPEYVAPEILYQRGHT 232 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 F VD+++ G + +EM G PPF++ D ++ + + S +LLKGLL D Sbjct: 233 FVVDFYSYGAMIYEMLCGSPPFYSKDKREMLKNRCEKPLEMKSCFSFYAASLLKGLLTKD 292 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPKL 315 P R+GS GI EIK H +FNG+DW+ + +KL P +P D NF P Q + Sbjct: 293 PGLRLGS--NGIQEIKKHNFFNGIDWKLVEQRKLQPPIIPKIQHVQDLQNFAPAFLQQPI 350 Query: 316 RKVSKYLYEEEFAEF 330 + + + E F F Sbjct: 351 METPESVSNEYFEGF 365 >UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme 1; n=28; Eumetazoa|Rep: cGMP-dependent protein kinase, isozyme 1 - Drosophila melanogaster (Fruit fly) Length = 768 Score = 235 bits (576), Expect = 9e-61 Identities = 118/303 (38%), Positives = 176/303 (58%), Gaps = 10/303 (3%) Query: 17 DKTVDDFDIVKAIGNGAYGEVFLVR----DKITFTYHAMKVVEKSVVVERNHAKHLILEK 72 D + D ++V +G G +G V LV+ D++ A+K ++K +V+ +H+ E+ Sbjct: 451 DLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDI--FALKCLKKRHIVDTKQEEHIFSER 508 Query: 73 KILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVIL 132 I+ + PF+ L F+D Y+Y +L GGE++T ++ G F D+ +F V+ Sbjct: 509 HIMLSSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQ 568 Query: 133 ALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVI 190 A EYLH +++RD+KPEN+++D GY+K+ DFGF K + KTWT CGTPEY+APE+I Sbjct: 569 AFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEII 628 Query: 191 TSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNL 248 +KG+ +VD+WALG L E+ G PPF A DP + Y +L G P+++S L Sbjct: 629 LNKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQL 688 Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFP 308 +K L + PS+R+G GGI +IK H WF G DW + Q LI PFV + P D F Sbjct: 689 IKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFD 748 Query: 309 EIP 311 P Sbjct: 749 RFP 751 >UniRef50_UPI00006CC8B4 Cluster: Protein kinase domain containing protein; n=2; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 464 Score = 234 bits (572), Expect = 3e-60 Identities = 116/295 (39%), Positives = 181/295 (61%), Gaps = 8/295 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+ F+++ IG G +G V LV+ K + AMK+++KS++ +R A +I EK IL Sbjct: 36 TLQSFELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKSIIRKRQFAHRIIQEKDILAFC 95 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 F+ L +F++ L+ IL Y +GG++F YI K S+ KFYA+Q++L LEYLH Sbjct: 96 NNNFMTKLHYSFQNQNNLFLILDYCSGGDLFNYISKKNTISEKDAKFYAAQIVLMLEYLH 155 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTWTLCGTPEYLAPEVITSKGYS 196 +V+RD+KPENILI+ NGYLKL DFG+ + + + ++CGTP Y PE+IT +G+ Sbjct: 156 SQNIVYRDLKPENILIEKNGYLKLGDFGYARQNMDSIEAKSVCGTPHYFPPEMITREGHG 215 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKV----LVGSYKCPENMSPECKNLLKGL 252 VDWWALG + +EM G PF S+ L++++ ++ + +S K+++ L Sbjct: 216 KPVDWWALGCVIYEMVFGATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKL 275 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 L+ + ++R+G+ I EIKSH WF+ +DW A+ +Q + APF+P D SNF Sbjct: 276 LKKNQNERLGT--ASIEEIKSHPWFDKMDWTALSNQTIAAPFIPAVKKVSDVSNF 328 >UniRef50_A0CNT4 Cluster: Chromosome undetermined scaffold_22, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_22, whole genome shotgun sequence - Paramecium tetraurelia Length = 362 Score = 234 bits (572), Expect = 3e-60 Identities = 115/295 (38%), Positives = 173/295 (58%), Gaps = 9/295 (3%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+D F ++ IG G+ G+V LVR K +A+KV++K+ ++E + K + E+ ILQ Sbjct: 30 TIDQFHLLSVIGKGSIGKVVLVRKKDNQKIYALKVIKKTKLIENHSVKQIFAERNILQNC 89 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 Q PF++ L+ AF++ LYF L Y GGE++ + + ++ KFYASQ+ILA +YLH Sbjct: 90 QHPFIIKLEYAFQNETKLYFCLQYCPGGELYQLLVQKNKLTEEQAKFYASQIILAFQYLH 149 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTW---TLCGTPEYLAPEVITSKGY 195 ++++RD+KPEN+LID GY+KL DFGF K + + + CGT EYLAPE++ + Sbjct: 150 EQDIIYRDLKPENVLIDQEGYIKLTDFGFSKQGIQGNFGAHSKCGTAEYLAPELLAG-NH 208 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPE-NMSPECKNLLKGLLQ 254 + DWW G L +EM G P FF +L+ ++L + S + K+LL LLQ Sbjct: 209 GKAADWWTFGTLIYEMVIGQPAFFGETKEELFNQILHHEINYKKIGASSQFKDLLSKLLQ 268 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 DP+ RI S EIK H WF +DW I +++ F+PI +S D F + Sbjct: 269 KDPNNRISSAN----EIKKHPWFKNIDWDMILKRQMPPVFIPILNSDDDVQYFDD 319 >UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 617 Score = 233 bits (569), Expect = 6e-60 Identities = 114/299 (38%), Positives = 180/299 (60%), Gaps = 7/299 (2%) Query: 17 DKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ 76 D ++D V +G G +G V LVR + TY A+K++ K+ +VE H++ E++IL Sbjct: 304 DVELEDLQRVSTLGMGGFGRVELVRSASSRTY-ALKIMNKAHIVETKQESHVVSERRILM 362 Query: 77 CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 ++V + ++D+ +Y ++ GGE++T ++K G F + LT+FY + + ALEY Sbjct: 363 QCDNDYIVRMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGAMEALEY 422 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK--KTWTLCGTPEYLAPEVITSKG 194 LH +V+RD+KPEN+L+D NG+ KL DFGF K LK +TWT CGT EY+APE++ +KG Sbjct: 423 LHRKNIVYRDLKPENMLLDRNGWPKLVDFGFAKKLKNGGRTWTFCGTAEYVAPEIVLNKG 482 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGL 252 + SVD WALG E+ G PPF ++DP Y +L G + P ++ E +++ L Sbjct: 483 HDLSVDIWALGIFMCELLTGSPPFSSTDPMVTYNAILKGLEKWAWPRFVTKEAIDMMLSL 542 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIP 311 + +P++R+G G I EI+ H WF+ D+ ++ PF+P ++ DTSNF P Sbjct: 543 CKYEPTERLGF--GDIGEIRHHIWFDNFDFVGFRAHRIRPPFIPSVANDIDTSNFDTFP 599 >UniRef50_P21901 Cluster: Spermatozoon-associated protein kinase; n=1; Aplysia californica|Rep: Spermatozoon-associated protein kinase - Aplysia californica (California sea hare) Length = 351 Score = 233 bits (569), Expect = 6e-60 Identities = 121/331 (36%), Positives = 193/331 (58%), Gaps = 6/331 (1%) Query: 4 EDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVR---DKITFTYHAMKVVEKSVVV 60 E F ++ I +++ ++ +++ +G+G++G V L + D Y A+K++ K VV Sbjct: 23 EQFENLFNKNVISTESIRNYTLIRTLGSGSFGRVMLSQHGGDNPQKCY-AIKILNKEKVV 81 Query: 61 ERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSD 120 + +H + EK+IL I PFVV AFKD LY ++ ++ GGE+F ++K G + Sbjct: 82 KMKQVEHTMNEKRILLSIGSPFVVRCLNAFKDTTNLYMVMEFVNGGELFHLLRKKGRLPE 141 Query: 121 SLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCG 180 FYA+QV +AL+YLH C +++RD+KPENIL+D GYLK+ DFGF + ++ TWTLCG Sbjct: 142 YWCTFYAAQVTMALQYLHNCSLLYRDLKPENILLDHLGYLKVTDFGFDRRVQGHTWTLCG 201 Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240 TP+YLAPE+I ++ Y+ LG L +E+ AG PF P KLYE ++ P Sbjct: 202 TPQYLAPEMILNRSYASQWTTGGLGILIYELNAGFVPFDHKVPLKLYELIVECRLTFPSF 261 Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300 P ++LL ++QVD ++R G+L+ G +I +H WF D++ I + AP+VP Sbjct: 262 FKPTLRDLLTNIIQVDVTRRFGNLRNGALDIINHPWFKDTDFRKILMKAEKAPWVPNLKG 321 Query: 301 PGDTSNFPEIPQPKLRKVSKY-LYEEEFAEF 330 F + + + +SK+ Y +EF+ F Sbjct: 322 QWIHQTFDKWTEESI-SISKHDKYPDEFSNF 351 >UniRef50_A2DS63 Cluster: AGC family protein kinase; n=3; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 453 Score = 232 bits (567), Expect = 1e-59 Identities = 107/300 (35%), Positives = 179/300 (59%), Gaps = 1/300 (0%) Query: 11 SDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLIL 70 S P ++DDF I+ +G G YG+V LV++K T A+K + K ++ E + + I Sbjct: 115 STTPAKKVSMDDFTILGVLGRGTYGKVQLVKEKETGKLFALKTMSKRLLAESDQVEQTIT 174 Query: 71 EKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQV 130 E+ +L + PF+V F+ + ++ +L Y+ GGE+F +++ +F++S + YA+++ Sbjct: 175 ERNVLLTTKHPFLVCAHYTFQTDAKIFMVLDYVPGGELFGRLKEESLFAESRVRLYAAEI 234 Query: 131 ILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK-KTWTLCGTPEYLAPEV 189 L L YLH ++RD+KPENIL+D +G+LK+ DFG K T T CGTPEY+APE+ Sbjct: 235 CLGLGYLHKLGFIYRDLKPENILVDQDGHLKITDFGLAKNTDMGTTSTFCGTPEYIAPEM 294 Query: 190 ITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLL 249 + Y+ +VDWW+ G + +EM G PPF+ + N++Y +L K P ++S + ++L+ Sbjct: 295 LQRLPYTKAVDWWSYGIIIYEMLTGLPPFYDENTNQMYRSILRDDVKYPSHVSHDARSLI 354 Query: 250 KGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 LL +P R+GS EIK+H +F ++W+ +F++K + P + DTS F E Sbjct: 355 NQLLNRNPEARLGSGPSDYEEIKAHPFFASINWENVFNKKTKPEWKPKIKNATDTSLFDE 414 >UniRef50_A0DVL2 Cluster: Chromosome undetermined scaffold_66, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_66, whole genome shotgun sequence - Paramecium tetraurelia Length = 488 Score = 232 bits (567), Expect = 1e-59 Identities = 107/283 (37%), Positives = 178/283 (62%), Gaps = 4/283 (1%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 DF +K IG G + V+LV+ K + ++AMK+++K +++E+ + E+ IL Q P Sbjct: 128 DFIFIKCIGVGGFSRVYLVKKKQSSRFYAMKIIDKKIIIEKKIENIIENERNILAVTQHP 187 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F+ L+ A + +L FI + AGG++ Y+QKY +F+++ +FY + IL L YLH + Sbjct: 188 FLNKLEYALECPNHLIFITEFCAGGDLLYYLQKYHVFTETQARFYIIEFILGLIYLHQLD 247 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK-TWTLCGTPEYLAPEVITSKGYSFSVD 200 +++RDIKPENILID G++++ DFG K + + ++ CG+PEY+APE++T++G++ +D Sbjct: 248 IIYRDIKPENILIDITGHIQIADFGLAKPTRNEYAYSFCGSPEYMAPEMLTNQGHNQQLD 307 Query: 201 WWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--MSPECKNLLKGLLQVDPS 258 + LG L +E+ G PPF++ D NK+YE +++ + P+N +S E K+L+ LL D Sbjct: 308 HYCLGVLLYELVVGQPPFYSEDINKIYENIILKEVEFPKNNTLSNEIKDLIVRLLDKDQK 367 Query: 259 KRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSP 301 RIG +GG+ EI H WF +D ++K+ PF P P Sbjct: 368 SRIGH-QGGLLEILDHKWFESVDLIKFLYRKVNPPFQPDVFKP 409 >UniRef50_Q8MYF1 Cluster: Similar to Dictyostelium discoideum (Slime mold). Protein kinase 2; n=2; Dictyostelium discoideum|Rep: Similar to Dictyostelium discoideum (Slime mold). Protein kinase 2 - Dictyostelium discoideum (Slime mold) Length = 456 Score = 231 bits (564), Expect = 2e-59 Identities = 112/291 (38%), Positives = 179/291 (61%), Gaps = 5/291 (1%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 + +F I +G G +G+VF V T +A+KV++K+ ++ + + + EK IL+ I Sbjct: 125 LSNFIIKHLVGKGGFGKVFQVVHVDTQKVYALKVIKKNHIIAKKSVVNTLAEKDILKKIS 184 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+V L AF++ LY ++ ++ GG++F ++QK IFS+ +FY +++ILALE+LH Sbjct: 185 HPFIVNLHYAFQNEKKLYLVMDFVNGGQLFYHLQKEAIFSEDQVRFYMAELILALEHLHD 244 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK---KTWTLCGTPEYLAPEVITSKGYS 196 +VHRD+KPENIL+DS G+ L DFG K+ K +T++ GT EY+APE+I Sbjct: 245 SNIVHRDLKPENILLDSQGHCILTDFGLAKLEVKTNNETFSFAGTLEYMAPEMIQHATCG 304 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 +VDWW++G L ++M G PPF + + EK++ K P+ +S ++L+ GLL D Sbjct: 305 KAVDWWSIGILMYDMMIGKPPFEHKNRALMQEKIISEKAKFPKFVSSSARSLINGLLTKD 364 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 P+KR+G+ G EIK H +F + W+ I ++++ PFVP D SNF Sbjct: 365 PTKRLGA--NGAIEIKRHPFFKSIQWRKIENKEITPPFVPSTKGIDDISNF 413 >UniRef50_Q4SYX7 Cluster: Chromosome 21 SCAF11909, whole genome shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 21 SCAF11909, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1114 Score = 230 bits (562), Expect = 4e-59 Identities = 124/320 (38%), Positives = 190/320 (59%), Gaps = 33/320 (10%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKS------------------------ 57 DFD +K IG G++G+V L R K T Y+A+KV++K Sbjct: 6 DFDYLKIIGKGSFGKVLLARHKETTKYYAVKVLQKKIIIKKKEVSARGAPSSPPVPEDVR 65 Query: 58 VVVERNHA---KHLILEKKIL-QCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQ 113 V++ R KH++ E+ +L + I+ PF+V L +F+ LYF+L Y+ GGE+F ++Q Sbjct: 66 VILNRKRLLQQKHIMAERSVLMKNIKHPFLVGLHYSFQTTDKLYFVLDYVNGGELFYHLQ 125 Query: 114 KYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---V 170 + IF + +FYA+++ AL YLH +V+RD+KPENIL+DS G++ L DFG CK Sbjct: 126 RERIFLEPRARFYAAEIASALGYLHSLHIVYRDLKPENILLDSQGHIVLTDFGLCKEGLE 185 Query: 171 LKKKTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKV 230 T T CGTPEYLAPEV+ + Y +VDWW LG + +EM G PPF++ + ++Y + Sbjct: 186 ANGTTTTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNI 245 Query: 231 LVGSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKL 290 L S N+S + LL+GLLQ D ++R+G +K E+K H++F+ ++W+ + +++ Sbjct: 246 LHKSPVLKPNVSNAGRELLEGLLQKDRARRLG-VKDDFLELKFHSFFSPINWEDLMAKRI 304 Query: 291 IAPFVPICSSPGDTSNF-PE 309 PFVP S P D +F PE Sbjct: 305 TPPFVPSVSGPTDLRHFDPE 324 >UniRef50_A2F9U6 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 279 Score = 229 bits (560), Expect = 8e-59 Identities = 98/256 (38%), Positives = 158/256 (61%) Query: 54 VEKSVVVERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQ 113 + K +++ +H+ EK IL + P +VT+ F+D +LY ++ +IAGGE+F++++ Sbjct: 1 MNKRQIIQLEQVEHVKNEKNILSILHHPNIVTVYGTFQDENFLYIMMEFIAGGEVFSHLR 60 Query: 114 KYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK 173 F +FYA++V + E +H +V+RD+KPEN+L D+ G++K DFGF K++++ Sbjct: 61 TNECFDPDTVRFYAAEVFMVFEEMHKNNIVYRDLKPENLLFDAGGHIKFIDFGFAKIIEE 120 Query: 174 KTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG 233 +T+TLCGTPEYLAPE+I +G +F+ DWW+ G L E+ GH PF + LY + G Sbjct: 121 RTYTLCGTPEYLAPEIIRGEGTTFASDWWSYGVLIHELICGHTPFAQLPEDDLYRSICEG 180 Query: 234 SYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 + P + N L L +DP++R+GS G EIK+H +F G+DW + + P Sbjct: 181 VSEYPPEVDEATANFLDALFALDPTRRLGSGSAGTDEIKNHPYFEGIDWNKMRAHQYQTP 240 Query: 294 FVPICSSPGDTSNFPE 309 +P+ +SP DTSNF + Sbjct: 241 LIPMVTSPYDTSNFAD 256 >UniRef50_P50530 Cluster: Serine/threonine-protein kinase sck1; n=1; Schizosaccharomyces pombe|Rep: Serine/threonine-protein kinase sck1 - Schizosaccharomyces pombe (Fission yeast) Length = 696 Score = 229 bits (560), Expect = 8e-59 Identities = 114/295 (38%), Positives = 180/295 (61%), Gaps = 9/295 (3%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL---QC 77 +DF ++ IG G +G+V+LVR T +AMK + K ++V + H + E+ IL Sbjct: 300 EDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTSL 359 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 + PF+V L +F+ LY I Y++GGE+F ++Q G F + KFY ++++LALE+L Sbjct: 360 DESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHL 419 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEV-ITSK 193 H ++++RD+KPENIL+D++G++ LCDFG K T T CGT EYLAPEV + K Sbjct: 420 HKHDIIYRDLKPENILLDADGHIALCDFGLSKANLSANATTNTFCGTTEYLAPEVLLEDK 479 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-MSPECKNLLKGL 252 GY+ VD+W+LG L FEM G PF+A D ++Y + G + P+ +S E ++ ++GL Sbjct: 480 GYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGVLSSEGRSFVRGL 539 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 L +P+ R+G++ E+K H +F ++W + +K+ PF P + D SNF Sbjct: 540 LNRNPNHRLGAV-ADTTELKEHPFFADINWDLLSKKKVQPPFKPNVQNDLDVSNF 593 >UniRef50_Q22RI5 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 394 Score = 229 bits (559), Expect = 1e-58 Identities = 110/314 (35%), Positives = 184/314 (58%), Gaps = 11/314 (3%) Query: 4 EDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERN 63 ++ N + S P ++ F+ +K IG G++G+V+LV+ K T +AMK++ K + + Sbjct: 18 QEINIRNSKMPQEKINLEHFEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKT 77 Query: 64 HAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLT 123 E+ IL+ + PFVV L AF+ LY ++ + GG++F ++ K F ++ Sbjct: 78 QLIQTKAERYILENVDSPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPFFPENKI 137 Query: 124 KFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCG 180 KFYA+++ LALE LH +V+RD+KPENIL+ + G++KL DFG K LK + T++ CG Sbjct: 138 KFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKLKSRDEITYSFCG 197 Query: 181 TPEYLAPEVITSKGYSFSVDWWAL--------GDLSFEMEAGHPPFFASDPNKLYEKVLV 232 T EY+APE+I+ +G+ + DWW+ G + +EM G PPF+ + ++ +K++ Sbjct: 198 TAEYMAPEIISKQGHDVASDWWSFFKYLNISKGAVLYEMLHGAPPFYEKNKERMMDKLVN 257 Query: 233 GSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIA 292 + S EC++LL+GLL D +KR+G+ G EI++H +FN +DW ++ Sbjct: 258 QDVVIKDKYSKECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFFNNVDWDKFLRLEVQP 317 Query: 293 PFVPICSSPGDTSN 306 P++P S D N Sbjct: 318 PYIPKVSDKYDLRN 331 >UniRef50_P34885 Cluster: Protein kinase C-like 1B; n=4; Bilateria|Rep: Protein kinase C-like 1B - Caenorhabditis elegans Length = 707 Score = 229 bits (559), Expect = 1e-58 Identities = 113/307 (36%), Positives = 185/307 (60%), Gaps = 6/307 (1%) Query: 7 NKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAK 66 ++ S P ++ DF +K +G G++G+V L K T +A+K+++K V+V+ + + Sbjct: 362 SRSASKVPGGTLSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVE 421 Query: 67 HLILEKKILQ-CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKF 125 + EK+IL + PF+ L +F+ + L+F++ Y+ GG++ IQ+ F +S +F Sbjct: 422 CTMCEKRILSLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARF 481 Query: 126 YASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTP 182 YA++V AL++LH +V++RD+K +NIL+D+ G+ +L DFG CK K T T CGTP Sbjct: 482 YAAEVTCALQFLHRNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGTP 541 Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242 +Y+APE++ Y SVDWWALG L +EM AG PPF A + + L+E +L P +S Sbjct: 542 DYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLS 601 Query: 243 PECKNLLKGLLQVDPSKRIGSL--KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300 E N+LK + + KR+G + +GG I++H +F +DW A+ +++ PF P S Sbjct: 602 KEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKS 661 Query: 301 PGDTSNF 307 D +NF Sbjct: 662 KRDANNF 668 >UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2; Endopterygota|Rep: Cgmp-dependent protein kinase - Aedes aegypti (Yellowfever mosquito) Length = 966 Score = 228 bits (558), Expect = 1e-58 Identities = 114/295 (38%), Positives = 174/295 (58%), Gaps = 5/295 (1%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 D + +G G +G V LVR + T+ A+K ++K +V + +H EK I+ P Sbjct: 657 DLTYIGTLGIGGFGRVELVRYQKQKTF-ALKYLKKIEMVRQQQQEHAYSEKDIMLSCNSP 715 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F+V L ++D YLYF++ GG+++T +QK F + +F A V+ A EYLH Sbjct: 716 FIVRLYKTYRDKKYLYFLMEACLGGDVWTILQKSKHFDERTARFMAGCVVEAFEYLHSRN 775 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYSFSV 199 +++RD+KPEN+++D GY+KL DFGF K + +KTWT GTPEY++PE+I +KG+ +V Sbjct: 776 MIYRDLKPENLMLDEQGYIKLVDFGFAKRIGANQKTWTFAGTPEYVSPEIILNKGHDRAV 835 Query: 200 DWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQVDP 257 D+WALG E+ G PPF + K Y +L G + P + + + L+K L + P Sbjct: 836 DYWALGVFIHELLVGKPPFRGKNHMKTYNAILRGIDIIELPSRIPKKAQVLIKRLCRQIP 895 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312 ++R+G K GI +IK+H WF+G +WQ + + L AP V S D SNF E P+ Sbjct: 896 AERLGYGKNGIADIKNHPWFSGFEWQRLKERTLPAPLVRPIQSDTDLSNFDEYPK 950 >UniRef50_O61225 Cluster: Serine/Threonine protein kinase; n=1; Sycon raphanus|Rep: Serine/Threonine protein kinase - Sycon raphanus Length = 724 Score = 228 bits (558), Expect = 1e-58 Identities = 115/323 (35%), Positives = 188/323 (58%), Gaps = 12/323 (3%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+ DF ++K +G G++G+V L + K + Y A+KV++K VV+E + + ++EK++L Sbjct: 393 TLSDFHLLKVLGKGSFGKVMLAQVKKSKQYLAIKVLKKDVVLEDDDVECTMIEKRVLSST 452 Query: 79 QF-PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 PF+V L AF+ +LYF++ Y+ GG++ +IQ+ G FS+ T+FY S++I L++L Sbjct: 453 SIHPFLVHLHSAFQTEGHLYFVMEYVNGGDLMFHIQQQGRFSEDRTRFYVSEIICGLQHL 512 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKG 194 H +++RD+K +N+++ S G++K+ DFG CK + T T CGTP+Y+APE+I + Sbjct: 513 HSRGIIYRDLKLDNVMLSSRGHIKIADFGMCKENICGENTTSTFCGTPDYIAPEIIQGEQ 572 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 Y+ SVDWWALG L++EM G PF D L++ ++ P ++ E + LL Sbjct: 573 YNHSVDWWALGVLTYEMLLGQSPFSGDDEESLFQSIMNDQVVYPVWLTREAAAFISKLLV 632 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF------- 307 +P KR+GS + +F +DW + ++ APFVP S GD NF Sbjct: 633 REPDKRLGS-DPKQSNPRGEAFFKTIDWAKLERAEIAAPFVPNVKSAGDACNFDVDFTME 691 Query: 308 PEIPQPKLRKVSKYLYEEEFAEF 330 P + P K+ K + +E F F Sbjct: 692 PAVITPTDEKLLKSMDQEPFNGF 714 >UniRef50_Q9UBS0 Cluster: Ribosomal protein S6 kinase beta-2; n=68; Eumetazoa|Rep: Ribosomal protein S6 kinase beta-2 - Homo sapiens (Human) Length = 482 Score = 228 bits (558), Expect = 1e-58 Identities = 110/293 (37%), Positives = 179/293 (61%), Gaps = 9/293 (3%) Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVER-NHAKHLILEKKILQC 77 F++++ +G G YG+VF VR K+ T +AMKV+ K+ +V H E+ IL+ Sbjct: 67 FELLRVLGKGGYGKVFQVR-KVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILES 125 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 ++ PF+V L AF+ LY IL ++GGE+FT++++ GIF + FY +++ LAL +L Sbjct: 126 VKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHL 185 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKG 194 H +++RD+KPENI++ S G++KL DFG CK + T T CGT EY+APE++ G Sbjct: 186 HSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSG 245 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 ++ +VDWW+LG L ++M G PPF A + K +K++ G P ++P+ ++L+K L+ Sbjct: 246 HNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLK 305 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +PS+RIG G +++ H +F ++W + ++ PF P S D S F Sbjct: 306 RNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQF 358 >UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, whole genome shotgun sequence; n=5; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_76, whole genome shotgun sequence - Paramecium tetraurelia Length = 864 Score = 228 bits (557), Expect = 2e-58 Identities = 107/283 (37%), Positives = 175/283 (61%), Gaps = 9/283 (3%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +D+ +K +G G +G V+LVR +A+K + K+ +VE++ +HL EK++L I Sbjct: 492 LDNLICIKKLGQGQFGNVYLVRTAQDEKLYALKCISKAQIVEQHLERHLAQEKQVLSTIN 551 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 FPF++ + KD Y+YF++ +I G E+F I++ G+ + S ++FY +++ +EYLH Sbjct: 552 FPFLMQFYKSMKDQNYIYFLVEFIKGMELFDAIREIGLLTTSDSQFYIGSLLICVEYLHK 611 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGYS 196 ++++RDIKPENI++D GYL++ D G K L +K T+T+ GTP Y+APE+IT KGY+ Sbjct: 612 LQIIYRDIKPENIMVDEKGYLRMIDMGTAKFLNQKSIRTYTIIGTPHYMAPEIITGKGYT 671 Query: 197 FSVDWWALGDLSFEMEAGHPPFF--ASDPNKLYEKVLVGSYKCPENM-SPECKNLLKGLL 253 FSVD W++G +E G P+ A DP ++YE++ S P M + K ++ LL Sbjct: 672 FSVDLWSIGVCLYEFMCGGVPYAEDADDPYEIYEEIQKKSITFPTFMKDKKAKKFIEQLL 731 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 P R+G GG +K++TWF+ DW + ++L PF+P Sbjct: 732 SKTPEARLG---GGYASLKANTWFDKFDWDKLMDKELKPPFLP 771 >UniRef50_Q4DL90 Cluster: Rac serine-threonine kinase, putative; n=2; Trypanosoma cruzi|Rep: Rac serine-threonine kinase, putative - Trypanosoma cruzi Length = 705 Score = 227 bits (556), Expect = 2e-58 Identities = 108/278 (38%), Positives = 173/278 (62%), Gaps = 7/278 (2%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 DF+++ IG G++G V R K T +A+K+++K VV+ + H EK IL I P Sbjct: 350 DFELLTVIGLGSFGRVMRARHKATGKIYALKILDKDQVVQHHLVPHTNAEKLILSEISHP 409 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 FVV L AF+ +L +L ++ GGE+F ++Q+ F ++ +FY +++ +A+EY+H Sbjct: 410 FVVKLYYAFQTKRHLILVLEFLCGGELFFHLQRCKRFDENRARFYTAEIGMAVEYIHSKS 469 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSFS 198 V++RD+KPEN+++D G++ L DFG K +T T CGTPEY+APE++ G++ + Sbjct: 470 VLYRDLKPENLVLDREGHVVLTDFGLAKRDVAEDVRTHTFCGTPEYMAPELVKKSGHTTA 529 Query: 199 VDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPS 258 VDWW+LG +EM G PPF++ + ++YE +L CP SPE K+LL LL+ DP Sbjct: 530 VDWWSLGAFLYEMVDGMPPFYSPNVAEMYEMILHKPLVCPARFSPELKSLLGRLLEKDPL 589 Query: 259 KRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 KR+ S + E ++H +FNGLD+ + +++ FVP Sbjct: 590 KRMTSGE----EFRAHPFFNGLDFDKLLRREIRPKFVP 623 >UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform a; n=5; Caenorhabditis elegans|Rep: Egg laying defective protein 4, isoform a - Caenorhabditis elegans Length = 780 Score = 227 bits (554), Expect = 4e-58 Identities = 118/316 (37%), Positives = 183/316 (57%), Gaps = 15/316 (4%) Query: 4 EDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLV---RDKITFTYHAMKVVEKSVVV 60 +DF ++++ T+ + + +G G +G V LV DK T+ A+K ++K +V Sbjct: 455 DDFREEFAQV-----TLKNVKRLATLGVGGFGRVELVCVNGDKAK-TF-ALKALKKKHIV 507 Query: 61 ERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSD 120 + +H+ E+ I+ ++V L F+D ++Y +L GGE++T ++ G F D Sbjct: 508 DTRQQEHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDD 567 Query: 121 SLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK--KKTWTL 178 +FY + V+ LEYLH +V+RD+KPEN L+ + GYLKL DFGF K L +KTWT Sbjct: 568 YTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTF 627 Query: 179 CGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYK 236 CGTPEY++PE+I +KG+ + D+WALG E+ G PPF ASDP K Y +L G + + Sbjct: 628 CGTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALE 687 Query: 237 CP-ENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFV 295 P + L+K L + +P +R+GS GG+ +I+ H WF G DW+ + + L P + Sbjct: 688 IPNRRIGKTATALVKKLCRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPIL 747 Query: 296 PICSSPGDTSNFPEIP 311 P S+P D +NF P Sbjct: 748 PKVSNPADVTNFDNYP 763 >UniRef50_A0DTL3 Cluster: Chromosome undetermined scaffold_63, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_63, whole genome shotgun sequence - Paramecium tetraurelia Length = 865 Score = 227 bits (554), Expect = 4e-58 Identities = 104/276 (37%), Positives = 173/276 (62%), Gaps = 5/276 (1%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 D F+I+K +G+GA+G+VFLV+ K AMK ++K ++ + K+ I E +L+ + Sbjct: 538 DSFEIIKELGSGAFGKVFLVKHKADGNIFAMKALKKKTLILKKQIKYAITEANVLKMCKH 597 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF++ L AF+ YLY +L Y GG++ +I G FS+ +FYA++++LA+E+LH Sbjct: 598 PFILGLHFAFQTPNYLYLVLDYCQGGDLSYHIANLGKFSEDTARFYAAEILLAIEFLHTK 657 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197 ++++RD+KPENIL+DS G++KL DFG K + K + CG+P YL+P++++ KG Sbjct: 658 DIIYRDMKPENILLDSQGHVKLADFGLSKEGVSDQDKAKSFCGSPAYLSPDILSQKGAGK 717 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 D + +G + +EM G P++ D ++Y+ + G+ K P+ MS E KNLL +L+ DP Sbjct: 718 PSDIYGIGCVMYEMMTGESPYYNDDIQQMYKNIQSGTLKWPKKMSVEAKNLLTKMLERDP 777 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 +KRIG+ EIK +F G+DW ++ ++ P Sbjct: 778 NKRIGTKSKD--EIKQDPFFKGIDWDKVYKRQYKPP 811 >UniRef50_Q9UK32 Cluster: Ribosomal protein S6 kinase alpha-6; n=145; Eumetazoa|Rep: Ribosomal protein S6 kinase alpha-6 - Homo sapiens (Human) Length = 745 Score = 227 bits (554), Expect = 4e-58 Identities = 116/294 (39%), Positives = 181/294 (61%), Gaps = 10/294 (3%) Query: 23 FDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 F+++K +G G++G+VFLVR K +AMKV++K+ + R+ + +E+ IL + Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTK-MERDILVEVN 131 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGYS 196 +V+RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+S Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 S DWW+ G L FEM G PF D N+ +L P+ +S E ++LL+ L + + Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRN 311 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309 P+ R+GS G+ EIK H +F +DW ++ +++ PF P P DT F PE Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPE 363 Score = 122 bits (293), Expect = 2e-26 Identities = 86/274 (31%), Positives = 143/274 (52%), Gaps = 27/274 (9%) Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPF 82 +++ + IG G+Y T A+K+++KS +R+ ++ + + +++ Q P Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKS---KRDPSEEIEI---LMRYGQHPN 479 Query: 83 VVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEV 142 ++TL F D Y+Y + + GGE+ I K FS+ + ++YLH V Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539 Query: 143 VHRDIKPENIL-ID---SNGYLKLCDFGFCKVLKKKTWTL---CGTPEYLAPEVITSKGY 195 VHRD+KP NIL +D S +++CDFGF K L+ + L C T ++APEV+ +GY Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGY 599 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPECKN 247 + D W+LG L + M AG+ P FA+ PN E++L +G+ K +N+S K+ Sbjct: 600 DAACDIWSLGVLFYTMLAGYTP-FANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKD 658 Query: 248 LLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLD 281 LL +L +DP +R + +I H+W D Sbjct: 659 LLSHMLHMDPHQRYTA-----EQILKHSWITHRD 687 >UniRef50_UPI0000499138 Cluster: hypothetical protein 53.t00028; n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical protein 53.t00028 - Entamoeba histolytica HM-1:IMSS Length = 964 Score = 226 bits (552), Expect = 7e-58 Identities = 112/293 (38%), Positives = 173/293 (59%), Gaps = 9/293 (3%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 DF+I+K I GAY V+LVR K+T +AMK+++K+ ++ +N ++ EK ILQ Q P Sbjct: 571 DFEIIKRINGGAYSSVYLVRKKVTNDIYAMKIMKKADMIRKNVVDGVLAEKTILQRAQTP 630 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 VV + AF+D L+ ++ Y GG++ + G ++ K Y+++++LALEY+H Sbjct: 631 SVVKMYYAFQDTHNLFLVMEYCPGGDLRCLLSNVGYLDETTAKIYSAEIVLALEYIHSLG 690 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWT-----LCGTPEYLAPEVITSKGYS 196 +HRD+KP+N+LID NG+L L DFG V K T L TP+Y+APE I S YS Sbjct: 691 CIHRDLKPDNVLIDKNGHLLLTDFGLSTVGSKIEQTVEDSRLVCTPDYVAPESIVSFQYS 750 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSP--ECKNLLKGLLQ 254 D+++LG + FE G PPF P+ +++ + G Y P +++P E K+++ GLL Sbjct: 751 RCSDYFSLGSMIFEFICGIPPFHEETPDAIFQNIRTGKYSWPSSINPSNELKSIVSGLLT 810 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 V+ KR+G + EIKSH WF G++W + ++ FVP + DT F Sbjct: 811 VEVKKRLG--YKSVQEIKSHPWFEGINWNTLLNESREDIFVPELDNETDTGYF 861 >UniRef50_A2FLX7 Cluster: AGC family protein kinase; n=4; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 469 Score = 225 bits (551), Expect = 9e-58 Identities = 112/304 (36%), Positives = 175/304 (57%), Gaps = 3/304 (0%) Query: 7 NKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAK 66 NK D +VDDFDI+K +G G+YG+V LV+ K T +AMK + K ++ E Sbjct: 130 NKVLGGKSASDVSVDDFDILKVLGKGSYGKVQLVKHKGTNQIYAMKSISKRLLGEYELVS 189 Query: 67 HLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFY 126 +I E+ +L I PF+V+ AF+ ++ +L Y+ GGE+F+ +++ F + ++Y Sbjct: 190 RIITERDVLLKINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLREERKFVEERARYY 249 Query: 127 ASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPE 183 +++ A+ YLH + HRD+KPENIL D +GY+KL DFG K K T T CGTPE Sbjct: 250 IAELAHAIGYLHSMGICHRDLKPENILFDKDGYIKLTDFGLVKEQMTKDATTTTFCGTPE 309 Query: 184 YLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSP 243 YLAPE++ Y +VDWWALG LS+EM G PPF+ + N +Y +L PE+ + Sbjct: 310 YLAPEMVAGNAYDNNVDWWALGTLSYEMLYGVPPFYDVNTNAMYRSILRDDIVFPEDATE 369 Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303 + + ++ LL +P+ R+GS E+ H +F +++ + +++ + P SS D Sbjct: 370 DAIDFIQKLLDKNPTTRLGSGPEDYKEVIGHKFFASINFDQLLKKQIPMQWKPQISSNTD 429 Query: 304 TSNF 307 S F Sbjct: 430 VSAF 433 >UniRef50_Q6UB97 Cluster: Protein kinase C 1; n=7; Dikarya|Rep: Protein kinase C 1 - Cryptococcus neoformans var. grubii (Filobasidiella neoformans var.grubii) Length = 1086 Score = 225 bits (551), Expect = 9e-58 Identities = 110/320 (34%), Positives = 190/320 (59%), Gaps = 10/320 (3%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78 +DDF+ + +G G +G+V L +K + +A+KV++K ++E + + EK++ Sbjct: 754 LDDFNFLAVLGKGNFGKVMLAEEKTSSNLYAIKVLKKEFIIENDEVESTQSEKRVFLAAA 813 Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + PF++ L F+ +YF++ YI+GG++ +IQK F+ KFYA +V+LAL+Y Sbjct: 814 QERHPFLLGLHSCFQTETRVYFVMEYISGGDLMLHIQKKQ-FTLRQAKFYACEVLLALQY 872 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193 H +++RD+K +NIL+ +G++K+ D+G CK K T T CGTPE++APE++ + Sbjct: 873 FHSKGIIYRDLKLDNILLTLDGHVKVADYGLCKEEMWFGKTTSTFCGTPEFMAPEILLEQ 932 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y +VDWWA G L++EM G PF D +++++ +L P M + +LL+ LL Sbjct: 933 RYGRAVDWWAFGVLTYEMLLGQSPFRGEDEDEIFDAILEDEPLYPITMPRDAVSLLQRLL 992 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE---I 310 DP++R+G+ +G EIK H +F +++ ++H+++ P+ P+ + DTSNF + Sbjct: 993 TRDPTRRLGAGEGDAEEIKQHLFFRDVNFDDVYHKRIPPPYFPVIGNATDTSNFDQEFTR 1052 Query: 311 PQPKLRKVSKYLYEEEFAEF 330 QP L V L E + EF Sbjct: 1053 EQPTLTPVHTQLSEADQKEF 1072 >UniRef50_UPI00006607B3 Cluster: RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).; n=1; Takifugu rubripes|Rep: RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta). - Takifugu rubripes Length = 518 Score = 225 bits (550), Expect = 1e-57 Identities = 116/332 (34%), Positives = 188/332 (56%), Gaps = 41/332 (12%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T++DF+ +K +G G +G+V LV++K T ++AMK++ K V++ ++ H + E ++LQ Sbjct: 147 TMNDFEYLKLLGKGTFGKVILVKEKATGVHYAMKILRKEVIIAKDEVAHTVTESRVLQNT 206 Query: 79 QFPFVV-------------------------TLDVAFKDNLYLYFILPYIAGGE------ 107 + PF+ TL AF+ + L F++ Y GGE Sbjct: 207 RHPFLTVRTLIMRQHLRQTHPPCDMIFLPPQTLKYAFQTHDRLCFVMEYANGGEVRPPAP 266 Query: 108 -------MFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYL 160 +F ++ + +F++ +FY ++++ ALEYLH +VV+RD+K EN+++D +G++ Sbjct: 267 YLSICFQLFFHMSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDLKLENLMLDKDGHI 326 Query: 161 KLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPP 217 K+ DFG CK + T T CGTPEYLAPEV+ Y +VDWW LG + +EM G P Sbjct: 327 KITDFGLCKEGITPDATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLP 386 Query: 218 FFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWF 277 F+ D +L+E +L+ + P N+SPE K+LL GLL+ DP +R+G E+ +H +F Sbjct: 387 FYNQDHERLFELILMEEIRFPRNLSPEAKSLLAGLLKKDPKQRLGGGPDDAKEVMTHKFF 446 Query: 278 NGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 ++WQ + +KL F P +S DT F E Sbjct: 447 TNINWQDVVQKKLTPLFKPQVTSETDTRYFDE 478 >UniRef50_Q234E6 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 829 Score = 225 bits (550), Expect = 1e-57 Identities = 114/286 (39%), Positives = 174/286 (60%), Gaps = 12/286 (4%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 + D ++K +G G +G VFLV++K + +K V K+ VVE++ KH+ EK++++ Sbjct: 496 LSDLIVIKKLGFGQFGSVFLVKEKGKKKLYGLKCVSKAQVVEQSLEKHIQNEKQVMEFNN 555 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 FPFV+ +FKD+ +YF+L +I G E+F I++ G+ S ++FY +IL LEYLH Sbjct: 556 FPFVMKFLRSFKDDRCIYFLLEFIQGMELFDVIREIGLLSTYDSQFYIGSLILTLEYLHS 615 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK------TWTLCGTPEYLAPEVITSK 193 +++RDIKPENI++D GYLKL D G K++K K T+T+ GTP Y+APEVI+ K Sbjct: 616 NYIIYRDIKPENIMVDHAGYLKLIDMGTAKIMKSKAGTVTRTFTIIGTPHYMAPEVISGK 675 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFF--ASDPNKLYEKVLVGSYKCPENMSPE-CKNLLK 250 GY+F VD W++G +E G+ PF A DP ++YE+++ + P M K L+ Sbjct: 676 GYNFLVDLWSVGICLYEFMCGYVPFAEEAEDPYEIYEEIIKKEIQFPAYMKDAVAKQLML 735 Query: 251 GLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 LL P R+G G +KS+ WF DW + +KL AP++P Sbjct: 736 QLLNKIPEIRLG---GSYNALKSNAWFKNFDWHQLLERKLKAPWIP 778 >UniRef50_O96997 Cluster: Protein kinase C; n=2; Tetractinomorpha|Rep: Protein kinase C - Geodia cydonium (Sponge) Length = 677 Score = 225 bits (549), Expect = 2e-57 Identities = 104/304 (34%), Positives = 185/304 (60%), Gaps = 6/304 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC- 77 ++ +F ++ +G G++G+VFL K + +A+K ++K ++V+ + + + E+K+L Sbjct: 343 SLGEFKLIVVLGKGSFGKVFLAEHKESKEVYAIKSLKKDLIVQEDDVECTLNERKVLALQ 402 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 + PF++ L F+ +L+F++ Y++GG++ +I + G FS+S T+FYA++++L L YL Sbjct: 403 SKPPFLINLHSCFQTEEHLFFVMEYVSGGDLMFHILELGRFSESQTRFYAAEIVLGLVYL 462 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKG 194 H +++RD+K +N+L+DS G++K+ DFG CK K T CGTP+Y+APE+I Sbjct: 463 HNLGIIYRDLKLDNVLLDSEGHVKIADFGLCKDGISGTSKARTFCGTPDYIAPEIIQYHP 522 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 Y +VDWWALG L +EM G PPF D ++L+ ++ P +S C+ ++ GLL Sbjct: 523 YDAAVDWWALGVLIYEMLVGRPPFDGDDDDQLFMNIVQKQVHYPRGLSEPCRKIISGLLT 582 Query: 255 VDPSKRIGS-LKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312 + SKR+GS + G+ IK+ +F +DW+ + +++ P+ P + NF PE + Sbjct: 583 KNASKRLGSHPEAGVDMIKAQPFFKNMDWEKLARREVKPPYRPKNKGKKNRDNFDPEFTK 642 Query: 313 PKLR 316 R Sbjct: 643 EPCR 646 >UniRef50_UPI0001509D2B Cluster: Protein kinase C terminal domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase C terminal domain containing protein - Tetrahymena thermophila SB210 Length = 408 Score = 224 bits (548), Expect = 2e-57 Identities = 118/295 (40%), Positives = 178/295 (60%), Gaps = 8/295 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+ F I++ IG+GA+G+V+LV K T +AMKV +K + E+N I E+ IL+ + Sbjct: 61 TLSSFRIIRVIGSGAFGKVYLVNKKGTEEVYAMKVYDKMTLYEKNVILSTIGERNILKNM 120 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 F+V L AF+ LY ++ ++ GGE++ +++K F + TKFY +QVILA+E LH Sbjct: 121 NSNFIVKLHYAFQAAQNLYLMMDFMVGGELYYHLKKAKKFDEERTKFYIAQVILAIECLH 180 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKK--TWTLCGTPEYLAPEVITSKGY 195 +++RD+K ENIL+ +GY+KL DFG K +K K T TLCGT EY+APE I ++G+ Sbjct: 181 QNNIMYRDLKLENILLGQDGYIKLTDFGLSKEGIKDKDLTNTLCGTAEYMAPEQIMNEGH 240 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFAS-DPNK--LYEKVLVGSYKCPENMSPECKNLLKGL 252 + D+W +G L++EM G PFF PNK ++ ++ G Y P+ + KN ++GL Sbjct: 241 NKMADFWQIGVLTYEMLYGTTPFFNEFRPNKDEIFNDIIQGKYTFPQYFKDDAKNFIRGL 300 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 LQ D KR+G G +E+K H +F DW + Q++ F P S D NF Sbjct: 301 LQKDVKKRLG--YNGFHELKKHAFFADFDWDKLERQEIEPQFKPPLRSQVDLQNF 353 >UniRef50_A2BIH5 Cluster: Novel protein similar to vertebrate protein kinase N2; n=4; Clupeocephala|Rep: Novel protein similar to vertebrate protein kinase N2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 970 Score = 224 bits (548), Expect = 2e-57 Identities = 104/297 (35%), Positives = 178/297 (59%), Gaps = 7/297 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++ DF V +G G +G+V L IT A+K ++K +V R+ + L+ EK+I + + Sbjct: 639 SLKDFKCVAVLGRGHFGKVLLAEYTITGEMFAIKALKKGDIVARDEVESLMCEKRIFETV 698 Query: 79 ---QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135 + PF+V L F+ ++ F++ Y AGG++ +I +FS+ FYA+ V+L L+ Sbjct: 699 NSVRHPFLVNLFACFQTKDHVCFVMEYAAGGDLMMHIHA-DVFSEPRATFYAACVVLGLQ 757 Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITS 192 +LH ++V+RD+K +N+L+D+ G++K+ DFG CK + +T T CGTPE+LAPEV+T Sbjct: 758 FLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYRDRTSTFCGTPEFLAPEVLTE 817 Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252 Y+ +VDWW LG L FEM G PF D ++++ ++ + P +S E ++++ L Sbjct: 818 TSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRVLSTEAISIMRRL 877 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 L+ +P +R+G+ + ++K H +F +DW + +K+ PFVP D SNF + Sbjct: 878 LRRNPERRLGAAERDAEDVKKHLFFRDIDWDGLLAKKVKPPFVPTIQCSSDVSNFDD 934 >UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101, whole genome shotgun sequence; n=17; Oligohymenophorea|Rep: Chromosome undetermined scaffold_101, whole genome shotgun sequence - Paramecium tetraurelia Length = 823 Score = 224 bits (548), Expect = 2e-57 Identities = 104/282 (36%), Positives = 175/282 (62%), Gaps = 8/282 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +DD +K +G G +G V+L ++K +A+K + K+ +VE++ HL EK +L+ +Q Sbjct: 495 LDDMIHIKKLGQGQFGSVYLCKNKKDGKLYALKCIIKNQIVEQHLENHLTQEKTVLEQVQ 554 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 FP ++ + KD+ ++YF++ YI G E+F I+ G+ + ++FY + ++L +EYLH Sbjct: 555 FPLMMRFYKSMKDDNFIYFLIEYIKGLELFDVIRDIGLLNTYDSQFYIASLLLCMEYLHT 614 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK--TWTLCGTPEYLAPEVITSKGYSF 197 +V+RDIKPEN+++D +GY++L D G K+LK K T+T+ GTP Y+APE++ KGYS+ Sbjct: 615 HHIVYRDIKPENVMVDHHGYIRLIDMGTAKILKGKGRTFTIIGTPHYMAPEILNGKGYSY 674 Query: 198 SVDWWALGDLSFEMEAGHPPFF--ASDPNKLYEKVLVGSYKCPENMSP-ECKNLLKGLLQ 254 SVD W++G +E G PF A DP ++YE++ P ++ + K + LL Sbjct: 675 SVDLWSIGICLYEFMCGGVPFAEDAEDPYEIYEEITKKQISYPNHLKDRKAKKFIDQLLN 734 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 P R+G G +K++TWF+GLDW + ++L P++P Sbjct: 735 KTPEIRLG---GSYAALKANTWFDGLDWDKLMDKELKPPYIP 773 >UniRef50_Q0UME1 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 1043 Score = 223 bits (546), Expect = 4e-57 Identities = 106/294 (36%), Positives = 176/294 (59%), Gaps = 7/294 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78 +D F+ + +G G +G+V L K T +A+KV++K ++E + + + EK++L Sbjct: 715 LDHFNFLAVLGKGNFGKVMLAETKSTKQLYAIKVLKKEFIIENDEVESVRSEKRVLLIAN 774 Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + PF+V L F+ +YF++ YI+GG++ +IQ+ G F +FYA++V LAL+Y Sbjct: 775 KERHPFLVNLHACFQTETRVYFVMEYISGGDLMLHIQR-GTFGTKRAQFYAAEVCLALKY 833 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193 H V++RD+K +NIL+ +G++K+ D+G CK T T CGTPE++APE++ K Sbjct: 834 FHENGVIYRDLKLDNILLTLDGHIKIADYGLCKEEMWYGSTTSTFCGTPEFMAPEILLDK 893 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y +VDWWA G L ++M PF D +++Y+ +L P +M + ++L+ LL Sbjct: 894 KYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLL 953 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +P R+GS EI SH +F ++W I+H+++ APF+P +S DTSNF Sbjct: 954 TREPEMRLGSGPTDAQEIMSHAFFRNINWDDIYHKRVPAPFIPTITSATDTSNF 1007 >UniRef50_O62570 Cluster: Protein kinase C-related kinase; n=1; Suberites domuncula|Rep: Protein kinase C-related kinase - Suberites domuncula (Sponge) Length = 1102 Score = 223 bits (544), Expect = 7e-57 Identities = 107/298 (35%), Positives = 178/298 (59%), Gaps = 7/298 (2%) Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77 K +DD+ + +G G +G+V + DK T A+KV++K +V R+ L+ EK+I + Sbjct: 768 KGLDDYAYMAVLGRGHFGKVLMAEDKKTKELVAIKVLKKGDIVARDEVDSLMSEKRIFET 827 Query: 78 ---IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILAL 134 I+ PF+V L F+ ++ F++ Y GG++ +I + IF + FYA+ V+L L Sbjct: 828 VNSIRHPFLVNLHSCFQTEQHVCFVMEYACGGDLMMHIHQ-DIFKEPRACFYAACVVLGL 886 Query: 135 EYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK---KKTWTLCGTPEYLAPEVIT 191 +YLH +V+RD+K +N+L+D +GY+K+ DFG CK +T T CGTPE+LAPEV+T Sbjct: 887 QYLHEKGIVYRDLKLDNLLLDKDGYVKIADFGLCKEGMWHGTRTSTFCGTPEFLAPEVLT 946 Query: 192 SKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKG 251 Y+ +VDWW LG L +EM G PF D ++++ ++ + P +S E ++++ Sbjct: 947 DVSYTRAVDWWGLGVLIYEMLVGESPFPGEDEEEVFDSIVNDDVRYPRFLSSEAISIMRK 1006 Query: 252 LLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 LL+ +P KR+G+ + +I+ +F +DW ++H+ + PF P+ S D SNF E Sbjct: 1007 LLRRNPEKRLGASERDAMDIRKQPFFRHIDWDKLYHKDIQPPFKPVLRSRLDISNFDE 1064 >UniRef50_UPI00006CB12C Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 1318 Score = 222 bits (543), Expect = 9e-57 Identities = 108/276 (39%), Positives = 174/276 (63%), Gaps = 4/276 (1%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 DF + IG G++GEV+LV K + +AMKV+ KS ++ N K+ + E+ ++ P Sbjct: 1006 DFIVHGLIGKGSFGEVYLVEKKGSQMLYAMKVLHKSKIIRHNLTKYAMTERNVMSLTNHP 1065 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F+V L+ AF+ + L+ I+ Y GG++ ++QK FS+ L K Y ++ ILALE LH + Sbjct: 1066 FIVKLNYAFQTSDKLFLIMDYCPGGDLGEHLQKEKKFSEELVKIYLAETILALEDLHKRD 1125 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW--TLCGTPEYLAPEVITSKGYSF 197 V+ RD+KP+NI++D G++KL DFG K VL + + CG+ YLAPE++ G+ Sbjct: 1126 VIFRDLKPDNIVLDYEGHVKLTDFGLSKEGVLDHSSGARSFCGSVAYLAPEMLKRCGHGK 1185 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 +VDW+ LG + +E+ G PP++A++ ++L+ + K P +S E ++LLK LLQ +P Sbjct: 1186 AVDWYLLGVVMYELLVGIPPYYANNRDELFYNIEKAPLKIPSYLSNEARSLLKALLQRNP 1245 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 +KR+GS KG EIK+H +F +DW ++ +KL P Sbjct: 1246 AKRLGSGKGDAEEIKAHPFFGDVDWNTVYQRKLKPP 1281 >UniRef50_Q7R5X8 Cluster: GLP_81_97826_96747; n=2; Giardia intestinalis|Rep: GLP_81_97826_96747 - Giardia lamblia ATCC 50803 Length = 359 Score = 222 bits (543), Expect = 9e-57 Identities = 110/300 (36%), Positives = 179/300 (59%), Gaps = 13/300 (4%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 D +K IG+G++G V L + T Y+A+K + K ++ H+ E IL+ ++ P Sbjct: 16 DLRHIKNIGSGSFGRVTLAQHIDTGKYYAVKAMSKRKIIALRQVAHINNECSILRVVRSP 75 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F++ ++D+ +Y IL +I GGE+F ++++Y F + KF+A +++LAL YLH Sbjct: 76 FIIRQYGTYQDDKNVYIILDFIQGGELFYHLRRYNKFPLQVVKFFAVEILLALGYLHNLG 135 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK----------TWTLCGTPEYLAPEVIT 191 + +RD+K EN+L+D+ G++KL D GF K L +K T+++ GTPEYLAPE+I Sbjct: 136 IAYRDLKLENVLVDNTGHIKLADLGFAKRLVEKNADGDTVSQLTFSIVGTPEYLAPEIIR 195 Query: 192 SKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKG 251 S G+ S DWWA G L +EM G PPFF +P+ +K+L G K+L+ Sbjct: 196 STGHDMSADWWAFGVLIYEMLTGSPPFFDDNPDMTCKKILGGKITFASGFDKAAKDLIIR 255 Query: 252 LLQVDPSKRIG-SLKGGIYEIKSHTWFNGLDWQAIFHQKLI-APFVPICSSPGDTSNFPE 309 LL D ++R+G S+ G +I H +F+G++W + F +K++ AP VP + P DT+N+ + Sbjct: 256 LLNPDKTRRLGASINNGTADIMKHAFFSGVNW-SWFEKKVVKAPIVPKLTDPADTANYED 314 >UniRef50_Q245J7 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 397 Score = 222 bits (543), Expect = 9e-57 Identities = 105/288 (36%), Positives = 182/288 (63%), Gaps = 7/288 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 + DF+I+K IG G++G+VF+V+ K +AMK + KS + +++ I EK I+ ++ Sbjct: 69 LSDFEILKVIGEGSFGKVFMVQKKDDGKIYAMKQLRKSNLTKQHQKLKTIEEKNIMVNMK 128 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+V L AF+ LYF++ ++ GGEMF +I+K F + + +FY S+++LALEYLH Sbjct: 129 SPFIVQLKYAFQTTTKLYFVMDFMQGGEMFYHIRKAKYFKEDVARFYVSELVLALEYLHS 188 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK---KTWTLCGTPEYLAPEVITSKGYS 196 + ++RD+KPENIL+ ++G++K+CDFG K K KT T+CGTPEYLAPE++ + + Sbjct: 189 KDTIYRDLKPENILLGADGHIKICDFGLSKQGVKDSDKTKTICGTPEYLAPEILLGQPHG 248 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 VDW++LG + +E +G PPF++ D ++Y++ + + + +L++ LL + Sbjct: 249 KEVDWYSLGCVLYEFLSGAPPFYSRDKQQMYQQRINSDIQRKPQFQNDAWDLIQLLLAKN 308 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304 P R+ + ++KSH +F +DW+ + ++ + PFV ++ DT Sbjct: 309 PKDRLNTAA----QVKSHPFFKTVDWEKLLNKDVRPPFVLKFNNEQDT 352 >UniRef50_O61224 Cluster: Serine/Threonine protein kinase; n=1; Sycon raphanus|Rep: Serine/Threonine protein kinase - Sycon raphanus Length = 756 Score = 222 bits (543), Expect = 9e-57 Identities = 102/292 (34%), Positives = 182/292 (62%), Gaps = 4/292 (1%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78 + DF +K +G G++G+V L + K Y+A+KV++K V+V+ + + ++EK++L Sbjct: 363 LSDFSFLKVLGKGSFGKVMLAQLKGQEQYYAIKVLKKDVIVQDDDVECTMIEKRVLALSG 422 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 + PF+ L F+ L+F++ ++ GG++ +IQ+ G F +++ FY+++++L L +LH Sbjct: 423 KPPFLTALHSTFQTKDRLFFVMEFVNGGDLMYHIQQQGRFKENVAVFYSAEIVLGLFFLH 482 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VL-KKKTWTLCGTPEYLAPEVITSKGY 195 V++RD+K +N+++D G++K+ DFG CK VL K+T T CGTP+Y+APE++ + Y Sbjct: 483 RHGVIYRDLKLDNVMLDHEGHIKIADFGMCKEGVLGAKQTRTFCGTPDYIAPEIVAYQPY 542 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 + SVDWWALG L +EM +G PPF D ++L+ +L + P++M+ E ++ K L Sbjct: 543 NGSVDWWALGVLVYEMLSGQPPFDGEDEDELFSSILGDEVRFPKSMTREACSICKSFLAK 602 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 P+ R+G G +I+ H ++ +DW + ++L PF P S +NF Sbjct: 603 HPAVRLGCGPNGEADIQGHPFYRTIDWTRLGRRELPPPFKPRIKSKNAANNF 654 >UniRef50_Q6C292 Cluster: Similar to sp|P24583 Saccharomyces cerevisiae YBL105c PKC1 ser/thr protein kinase; n=1; Yarrowia lipolytica|Rep: Similar to sp|P24583 Saccharomyces cerevisiae YBL105c PKC1 ser/thr protein kinase - Yarrowia lipolytica (Candida lipolytica) Length = 1252 Score = 222 bits (543), Expect = 9e-57 Identities = 98/296 (33%), Positives = 178/296 (60%), Gaps = 6/296 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +DDF+ + +G G +G+V L K T +A+KV++K ++E + + E+++ Q Sbjct: 922 LDDFNFLAVLGKGNFGKVMLAESKKTTNLYAIKVLKKDFIIENDEVESTRSERRVFQIAN 981 Query: 80 ---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 PF++ L F+ +YF++ Y++GG++ +IQK G+F +FYA++V+L +++ Sbjct: 982 RESHPFLLNLYSCFQTENRVYFVMDYVSGGDLMWHIQKEGVFKPGRAQFYAAEVLLGIKH 1041 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193 H V++RD+K +NIL+ +G++K+ D+G CK + T T CGTPE++APE++ + Sbjct: 1042 FHDNGVIYRDLKLDNILLTRDGHVKIADYGLCKEDMDYGRTTGTFCGTPEFMAPEILLEQ 1101 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y +VDWWA G L ++M G PF D +++++ +L + P + C ++L LL Sbjct: 1102 RYGLAVDWWAFGVLIYQMVLGQSPFRGEDEDEIFDAILADEPRYPITLPGNCVSILTQLL 1161 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 +P +R+GS EI +H +F +++ I+H+++ PFVP +SP D +NF + Sbjct: 1162 TREPERRLGSGPRDAEEIMAHPYFANVNFDDIYHKRIPPPFVPKITSPTDVTNFDQ 1217 >UniRef50_P23443 Cluster: Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha); n=19; Bilateria|Rep: Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) - Homo sapiens (Human) Length = 525 Score = 222 bits (543), Expect = 9e-57 Identities = 107/292 (36%), Positives = 177/292 (60%), Gaps = 7/292 (2%) Query: 23 FDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVVER-NHAKHLILEKKILQCI 78 F++++ +G G YG+VF VR T AMKV++K+++V H E+ IL+ + Sbjct: 91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 150 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 + PF+V L AF+ LY IL Y++GGE+F +++ GIF + FY +++ +AL +LH Sbjct: 151 KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLH 210 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGY 195 +++RD+KPENI+++ G++KL DFG CK T T CGT EY+APE++ G+ Sbjct: 211 QKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGH 270 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 + +VDWW+LG L ++M G PPF + K +K+L P ++ E ++LLK LL+ Sbjct: 271 NRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKR 330 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 + + R+G+ G E+++H +F ++W+ + +K+ PF P+ S D S F Sbjct: 331 NAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQF 382 >UniRef50_A2EEZ5 Cluster: AGC family protein kinase; n=2; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 417 Score = 222 bits (542), Expect = 1e-56 Identities = 108/287 (37%), Positives = 169/287 (58%), Gaps = 6/287 (2%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 DF I+ +G G YG+V L + T +A+K + K ++V + ++ + E+ +L + P Sbjct: 105 DFRIISVLGRGYYGKVMLCEENTTKELYAIKTIHKKMLVNSDKVQNALTERNVLVRVHHP 164 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F+V+L F+ LYF + Y GGE+F ++++ G F + Y +++ LA+EYLH Sbjct: 165 FIVSLKTTFQTPTKLYFAMEYAPGGELFFHLERKGAFHIHDVRIYVAELALAIEYLHDNN 224 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTW-TLCGTPEYLAPEVITSKGYSFSVD 200 +++RDIKPENIL+DS G++K+ DFG K +++ T TLCG+P Y+APE+IT Y +VD Sbjct: 225 IIYRDIKPENILLDSEGHVKITDFGLSKEMEEDTTSTLCGSPNYMAPEIITHTRYGPAVD 284 Query: 201 WWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKR 260 WW+LG L +EM G PF + + L + P N +P+ ++L+ GLLQ +PS+R Sbjct: 285 WWSLGILMYEMLFGVQPFVNENKSVLLMMIATCRVSFPRNANPDAQSLILGLLQKNPSER 344 Query: 261 IGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 G +IKSH +F G D+ +K+ FVPI D NF Sbjct: 345 F-----GFEQIKSHPFFQGRDFDDYLQKKVKPIFVPISLRRTDPVNF 386 >UniRef50_Q5QFC4 Cluster: EnvDll2-01; n=1; Oikopleura dioica|Rep: EnvDll2-01 - Oikopleura dioica (Tunicate) Length = 703 Score = 221 bits (541), Expect = 2e-56 Identities = 123/295 (41%), Positives = 174/295 (58%), Gaps = 29/295 (9%) Query: 18 KTVDDFDIVKAIGNGAYGEVFLVR-DKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ 76 KTV D DIVK +G G +G V LV+ I A+K ++K+ VVE H++ EK IL Sbjct: 411 KTVKDLDIVKPLGAGGFGVVKLVKVSGIKNKAFALKYIQKARVVEYGQESHVVDEKNILG 470 Query: 77 CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 ++ PF++ L FK G F DS+ +FYA VI A +Y Sbjct: 471 LMKSPFILGLLRTFK------------------------GPFKDSVARFYAGCVINAFDY 506 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK-VLK-KKTWTLCGTPEYLAPEVITSKG 194 +H + +RD+KPEN+++D GY++L D GF K VL KTWT CGTPEY++PE+IT+ G Sbjct: 507 MHSRDYCYRDLKPENLMVDEKGYVRLVDLGFAKKVLPGHKTWTFCGTPEYISPEIITNSG 566 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGL 252 ++ S D W LG L FE+ PFFA + +YEK+L G + P +S + ++L+K L Sbjct: 567 HNVSADLWCLGILIFELLCRKTPFFAKNDMDIYEKILQGIHAVSIPFRVSRKAESLIKQL 626 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 + DPS+RIG K G +I+ H W+ G DW+A+ ++K+IAP VP SS D SNF Sbjct: 627 CKRDPSERIGYQKDGFEDIRRHRWYAGFDWEALENEKMIAPHVPYISSFEDCSNF 681 >UniRef50_Q22HC2 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 436 Score = 221 bits (540), Expect = 2e-56 Identities = 105/285 (36%), Positives = 176/285 (61%), Gaps = 5/285 (1%) Query: 26 VKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVT 85 + +G G++G+V LV K T +AMK+++K + N + E+ IL + PF+V Sbjct: 76 IHVLGKGSFGKVVLVEKKDTKELYAMKILKKDYIQYTNQKFNTQQERDILVKMNSPFIVK 135 Query: 86 LDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHR 145 L AF+ LY ++ ++ GGE+F ++++ IF++ +Y++++IL +E LH +++R Sbjct: 136 LHYAFQTADKLYIVMDFMIGGELFYHLRRSPIFTEEKAAYYSAEIILGIEALHSNNIIYR 195 Query: 146 DIKPENILIDSNGYLKLCDFGFCKVLKK---KTWTLCGTPEYLAPEVITSKGYSFSVDWW 202 D+KPENILID G+L+L DFG K K +T +LCGTPEYLAPE++ + G++ VDWW Sbjct: 196 DLKPENILIDHKGHLRLADFGLSKKGVKDHERTNSLCGTPEYLAPEILLNNGHTKMVDWW 255 Query: 203 ALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRIG 262 +LG + +EM G PPF+ + ++++ + + E SP K+LL GLL ++P R+G Sbjct: 256 SLGAIIYEMLTGAPPFYNKNQKQMFKDRFLKPIEMKEWFSPAAKSLLSGLLNINPELRLG 315 Query: 263 SLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 GI EIK H ++ ++W ++ +++ P+ P SS D S+F Sbjct: 316 F--KGIQEIKEHEFYASINWDKLYKKEIPPPYKPKLSSKYDLSHF 358 >UniRef50_UPI0000D5755E Cluster: PREDICTED: similar to ribosomal protein S6 kinase, 90kDa, polypeptide 5 isoform a; n=2; Endopterygota|Rep: PREDICTED: similar to ribosomal protein S6 kinase, 90kDa, polypeptide 5 isoform a - Tribolium castaneum Length = 928 Score = 221 bits (539), Expect = 3e-56 Identities = 111/304 (36%), Positives = 189/304 (62%), Gaps = 17/304 (5%) Query: 23 FDIVKAIGNGAYGEVFLVRDK---ITFTYHAMKVVEKSVVVERNHA-KHLILEKKILQCI 78 FD++K +G GAYG+VFLVR + +AMKV++K+ +V++ +H E+++L+ + Sbjct: 73 FDLLKVLGTGAYGKVFLVRKRGGADNNRLYAMKVLKKATIVQKKKTTEHTKTERQVLEAV 132 Query: 79 QF-PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 + PF+VTL AF+ + L+ IL Y+AGGE+FT++ + F++ + Y ++ILALE L Sbjct: 133 RDNPFLVTLHYAFQTDAKLHLILDYVAGGELFTHLYQREHFTEDEVRIYIGEIILALERL 192 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK------KTWTLCGTPEYLAPEVIT 191 H +++RDIK ENIL+D +G++ L DFG K L + + ++ CGT EY+APEV+ Sbjct: 193 HSLGIIYRDIKLENILVDESGHIVLTDFGLSKELPREGDNDQRAYSFCGTIEYMAPEVVK 252 Query: 192 --SKGYSFSVDWWALGDLSFEMEAGHPPFFA----SDPNKLYEKVLVGSYKCPENMSPEC 245 ++G+ +VDWW++G L++E+ G PF + ++ ++L + P+++ + Sbjct: 253 GGTQGHDIAVDWWSVGVLTYELLTGASPFTVEGEKNTQQEISRRILKTTPPIPDSLGKDV 312 Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305 + + LL DP KR+G +G E+K H++F LDW+ + +++ APF P+ S D S Sbjct: 313 ADFISKLLVKDPRKRLGGGEGDAKELKKHSFFKSLDWEKLARKEIPAPFKPVIRSELDVS 372 Query: 306 NFPE 309 NF E Sbjct: 373 NFSE 376 Score = 118 bits (285), Expect = 2e-25 Identities = 68/200 (34%), Positives = 112/200 (56%), Gaps = 15/200 (7%) Query: 77 CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 C P +VTL +D + Y +L Y+ GGE+F I+K F++S +++ A+ + Sbjct: 495 CQGHPNIVTLHDVIQDEAHTYLVLEYLKGGELFERIRKKSKFTESEASGILRKLVSAVSF 554 Query: 137 LHYCEVVHRDIKPENILI---DSNGYLKLCDFGFCKVLKKK--TWTLCGTPEYLAPEVIT 191 +H C VVHRD+KPEN++ D + +K+ DFGF ++ ++K T C T Y APEV+ Sbjct: 555 MHSCGVVHRDLKPENLVFTDDDDSAEIKVIDFGFARLKQEKESLHTPCFTLHYAAPEVLK 614 Query: 192 S--KGYSFSVDWWALGDLSFEMEAGHPPFFA--SDPN--KLYEKVLVGSYKCPEN----M 241 +GY + D W+LG + + M G PF A D N + E++ G + + + Sbjct: 615 GDPEGYDENCDLWSLGVILYTMLCGKAPFHARSRDENVSSIMERIKEGDFNFNSSAWTGV 674 Query: 242 SPECKNLLKGLLQVDPSKRI 261 S E K++++GLL V+P +R+ Sbjct: 675 SNEAKSVVRGLLTVNPGQRL 694 >UniRef50_Q24DD1 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 449 Score = 220 bits (538), Expect = 4e-56 Identities = 107/281 (38%), Positives = 178/281 (63%), Gaps = 8/281 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++ DF I + +G GA+G+V+LV K + +AMK ++K +V+ + ILEK IL Sbjct: 100 SIQDFVIDRPLGKGAFGQVYLVTKKDSQRKYAMKTIKKIDMVKLQLIEATILEKTILLKS 159 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L + +Y I+ YI GGE+FT ++ G F++ + KF +++IL ++YLH Sbjct: 160 SHPFIVQLKYCIQTEKKIYLIMEYIQGGELFTLLKHCGQFTEKVAKFIIAEIILGIQYLH 219 Query: 139 -YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK---KKTWTLCGTPEYLAPEVITSKG 194 ++++RDIKPENIL+ +G++K+ DFG K + +KT+T GTPEYLAPE++ +KG Sbjct: 220 ETLKIIYRDIKPENILLTKSGHIKISDFGLSKEFQNKDEKTYTFAGTPEYLAPEIVLNKG 279 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPN--KLYEKVLVGSYKCPENMSPECKNLLKGL 252 ++ +VD W +G +E+ AG+PPF + N K+ +++++ PEN SP K+L+K L Sbjct: 280 HNKNVDLWGIGVFLYELVAGYPPFQDKNRNYDKISKQIIMNRPTYPENFSPNLKDLIKKL 339 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 L DP R+G+ ++K H +F +DW+A+ + K+ +P Sbjct: 340 LNSDPQMRLGA--NSFTDLKEHPFFYDVDWEALENLKIESP 378 >UniRef50_Q16QY2 Cluster: Ribosomal protein S6 kinase, 90kD, polypeptide; n=1; Aedes aegypti|Rep: Ribosomal protein S6 kinase, 90kD, polypeptide - Aedes aegypti (Yellowfever mosquito) Length = 1037 Score = 220 bits (538), Expect = 4e-56 Identities = 111/304 (36%), Positives = 189/304 (62%), Gaps = 13/304 (4%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDK---ITFTYHAMKVVEKSVVVERNH-AKHLILEKKI 74 ++DDF ++K +G GAYG+VFLVR +AMKV++K+ + ++ A+H E+++ Sbjct: 25 SMDDFKLLKVLGTGAYGKVFLVRKLGGVDNNKLYAMKVLKKATICQKKKTAEHTRTERQV 84 Query: 75 LQCIQ-FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133 L+ I+ PF+VT+ AF+ L+ IL Y++GGE+FT++ F++ + Y +++I+A Sbjct: 85 LESIKRSPFLVTMHYAFQTESKLHIILDYVSGGELFTHLYNKEHFTEDEVRIYIAEIIVA 144 Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVI 190 LE LH +++RDIK ENILIDS G++ L DFG + L ++ + CGT EY+APE++ Sbjct: 145 LEQLHKLGIIYRDIKLENILIDSEGHIVLTDFGLSRELVYENERAHSFCGTIEYMAPEIV 204 Query: 191 TS--KGYSFSVDWWALGDLSFEMEAGHPPFFASD---PNKLYEKVLVGSYKCPENMSPEC 245 S G+ +VDWW++G L+FE+ G PF + + ++ +K+ P+++S E Sbjct: 205 KSNQNGHDQTVDWWSVGVLTFELLTGSSPFSSEESVTQTEISKKITNTEAVIPDHLSREA 264 Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305 K+ ++ LL DP +R+G E+KSH +F ++W+ + +K+ APF P+ DT+ Sbjct: 265 KDFIRKLLVKDPRRRLGGGSADASELKSHDFFKSINWRQLADKKISAPFRPVIEDELDTN 324 Query: 306 NFPE 309 NF + Sbjct: 325 NFSD 328 Score = 113 bits (271), Expect = 8e-24 Identities = 80/259 (30%), Positives = 130/259 (50%), Gaps = 27/259 (10%) Query: 27 KAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTL 86 +AIG+G + R + Y+A+KV+ +A+ + + + +C P +V Sbjct: 398 RAIGDGLFSTCLKCRRLSSSKYYAVKVLFNHPE-PAEYARREV--EALKECQGHPNIVKF 454 Query: 87 DVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRD 146 KD+ ++Y +L + GGE+ I K F+DS + Y Q++ A+ Y+H + H D Sbjct: 455 VEVLKDSHHIYIVLELLGGGELLHRINKTSSFTDSQARHYFRQMVQAVAYMHQKGIAHCD 514 Query: 147 IKPENILID--SNGYLKLCDFGFCKVLKKK----TWTLCGTPEYLAPEVITSKGYSF-SV 199 +KPEN+L + S+ +LKL DF F K ++ + + GT Y APEV + Y+ S Sbjct: 515 LKPENVLFEGPSSEHLKLIDFSFAKSIENNNCLVSSPIAGTLGYSAPEVFDGRSYALESS 574 Query: 200 DWWALGDLSFEMEAGHPPF----------FASDPNK---LYEKVLVGSYKCP----ENMS 242 D W+LG + + M G PF AS + + +K+ GS+ E +S Sbjct: 575 DLWSLGVILYTMLCGQAPFTPRQFFGHTNLASSAKQMEIIMDKIRRGSFDLAASAWECVS 634 Query: 243 PECKNLLKGLLQVDPSKRI 261 E K+L+K LL VDP +RI Sbjct: 635 EEAKDLVKRLLTVDPDRRI 653 >UniRef50_UPI00006CB3D2 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 327 Score = 220 bits (537), Expect = 5e-56 Identities = 114/278 (41%), Positives = 168/278 (60%), Gaps = 8/278 (2%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYH--AMKVVEKSVVVERNHAKHLILEKKILQ-CI 78 ++ +++ IGNG YG+V L +D A+K++ K+ +N + E+ IL+ C Sbjct: 15 NYKVLELIGNGTYGDVVLAQDLRGNGDEQVAIKII-KNNKERKNQISSIQNERIILEKCK 73 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF V KD +FI+ Y+ GGE++ IQ G S+ +FYASQV++AL+YLH Sbjct: 74 NHPFFVQSKEFVKDKSCSFFIMEYVQGGELYDIIQNRGHLSEDAARFYASQVLIALDYLH 133 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGF--CKVLKKKTWTLCGTPEYLAPEVITSKGYS 196 ++V+RD+KPENIL+D NGY+KL DFG +V+ +CGTPEY++PE++ GY Sbjct: 134 QNDIVYRDLKPENILLDENGYVKLTDFGLSEVEVVSPTLDKICGTPEYVSPEMLFESGYG 193 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 VD WALG L FEM GH PF A +L+EK+ P +SP+ K+LL+GL + Sbjct: 194 KQVDHWALGVLIFEMITGHTPFEAKSQEELFEKIKFSQVTYPACISPQLKSLLEGLFMKN 253 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPF 294 PSKR+G+ GI +IK H WF W+++ + L AP+ Sbjct: 254 PSKRLGA--KGIEQIKKHPWFIKTSWESLKKKLLKAPY 289 >UniRef50_P16911 Cluster: Protein kinase DC1; n=5; Sophophora|Rep: Protein kinase DC1 - Drosophila melanogaster (Fruit fly) Length = 376 Score = 220 bits (537), Expect = 5e-56 Identities = 104/234 (44%), Positives = 152/234 (64%), Gaps = 2/234 (0%) Query: 29 IGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLDV 88 +GNG++G V LVR+K Y+A K++ K +V H+ EK +L +FPF++ L Sbjct: 51 LGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVD 110 Query: 89 AFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIK 148 + K YLY ILP + GGE+F+Y ++ F++ +FYA+QV LALEY+H +++RD+K Sbjct: 111 STKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLK 170 Query: 149 PENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLS 208 PENIL+D GY+K+ DFGF K + +T TLCGTPEYLAPE++ + Y+ SVDWWA G L Sbjct: 171 PENILLDQRGYIKITDFGFTKRVDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILV 230 Query: 209 FEMEAGHPPF--FASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKR 260 +E AG PF D +Y K+ + YK P + + ++L++ L+QVD SKR Sbjct: 231 YEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLMQVDTSKR 284 >UniRef50_Q8MUA6 Cluster: Protein kinase C-related kinase; n=1; Hydra vulgaris|Rep: Protein kinase C-related kinase - Hydra attenuata (Hydra) (Hydra vulgaris) Length = 1030 Score = 219 bits (536), Expect = 6e-56 Identities = 104/295 (35%), Positives = 175/295 (59%), Gaps = 7/295 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC- 77 ++++F + +G G +G+V L K T A+K ++K ++ R+ L+ EK+I + Sbjct: 699 SMENFRCISVLGRGHFGKVLLAEYKTTKELFAIKALKKGDIISRDEVDSLMSEKRIFETA 758 Query: 78 --IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135 ++ PF+V L F+ ++ F++ Y GG++ +I + +FS+ T FY+ VIL L+ Sbjct: 759 NSVRHPFLVNLFSCFQTKDHVCFVMEYAPGGDLMMHIHEE-VFSEPRTIFYSGCVILGLQ 817 Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITS 192 YLH ++V+RD+K +N+L+D+ GY+K+ DFG CK +KT T CGTPE+LAPEV+T Sbjct: 818 YLHEHDIVYRDLKLDNLLLDAEGYVKIADFGLCKEGMGFGQKTGTFCGTPEFLAPEVLTE 877 Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252 Y+ +VDWW LG L FEM G PF D ++++ ++ + P +S + L++ L Sbjct: 878 TSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSNDSIALMRRL 937 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 L+ +P +R+GS +IK ++ + W ++ +KL PF+P P D SNF Sbjct: 938 LRKNPERRLGSSIKDAEDIKKQPFYKDMKWDSLIQRKLKTPFIPTVKHPEDVSNF 992 >UniRef50_Q23YB5 Cluster: Protein kinase domain containing protein; n=8; Oligohymenophorea|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 551 Score = 219 bits (536), Expect = 6e-56 Identities = 101/296 (34%), Positives = 180/296 (60%), Gaps = 19/296 (6%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSV--------------VVERNH 64 T++DF+++K +G GA+G+V LV +K T +A+K + K +++++ Sbjct: 195 TINDFNLLKVLGRGAFGKVMLVEEKSTKKIYALKSIRKLASFLVGSLNKQNQEDIIDKDQ 254 Query: 65 AKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTK 124 +H E+ IL+ PF+V L AF ++F+ ++ GGE+F +++ F ++ + Sbjct: 255 IEHTKTERVILEHCNHPFLVNLVYAFTTPEKIFFVTQFMKGGELFQHLKHAKRFDENRAR 314 Query: 125 FYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK--TWTLCGTP 182 FY +++ LAL +LH +++RD+KPENIL+D +G++ L DFG K+++K + CGTP Sbjct: 315 FYVAEIALALGHLHKKSIIYRDLKPENILMDEHGHICLTDFGMAKIVRKNELAMSFCGTP 374 Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240 EYL+PE+I+ G++ S DWWALG ++EM PPF+ + +++++ + + P+ Sbjct: 375 EYLSPEIISGVGHTISCDWWALGIFTYEMLFALPPFYTQNQDQMFKAIKESQIRFPDKIA 434 Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 +SPE +N + + DP +R+G+ G + EIKSH W G+DW+A+ ++ PF P Sbjct: 435 ISPEAQNFILSCCKKDPHQRLGT-HGDLEEIKSHPWLAGMDWEALLNKTAEPPFKP 489 >UniRef50_A0DLX8 Cluster: Chromosome undetermined scaffold_56, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_56, whole genome shotgun sequence - Paramecium tetraurelia Length = 371 Score = 219 bits (536), Expect = 6e-56 Identities = 120/293 (40%), Positives = 177/293 (60%), Gaps = 17/293 (5%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++D F++ IG G Y +V LVR K T +A+KV++KS + + A+ +E+ I+ I Sbjct: 23 SLDSFEMNCVIGKGQYAKVLLVRKKDTKHLYALKVLKKSGL--KQDAR---IERNIMIEI 77 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 Q PF++ L AF+ +LYF + Y GGEM+ + K FS+ FYA+Q+ILALEYLH Sbjct: 78 QHPFIIKLVYAFQTASHLYFCMEYCPGGEMYYLLSKQKHFSEHTAMFYAAQIILALEYLH 137 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK----VLKKKTWTLCGTPEYLAPEVITSKG 194 ++ RD+KPENI+I +GY+KL DFG CK ++CGTP Y+APE++ SK Sbjct: 138 SKGIIFRDLKPENIVICQDGYVKLTDFGLCKKGDFTNISGASSICGTPAYMAPEILLSKQ 197 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 Y +VDWWA G +EM AGHPPFFAS+ L E +V S + S + ++LL LL+ Sbjct: 198 YGKAVDWWAFGCFLYEMVAGHPPFFASNKQDL-EYSIVNSQPNMGHFSIKLQDLLYRLLE 256 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +P R+ + ++ H WFN +D+ AI ++K APF+P + D + F Sbjct: 257 KNPKNRLTT------NVRDHQWFN-IDFDAILNKKETAPFLPTLQNEADVTYF 302 >UniRef50_Q22LX8 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 679 Score = 219 bits (535), Expect = 8e-56 Identities = 101/276 (36%), Positives = 172/276 (62%), Gaps = 5/276 (1%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 +DF IV+ +G GA+G+VFLV+ K + AMKV++K ++ +N K+ + E+ +L +Q Sbjct: 350 NDFTIVETLGKGAFGQVFLVQKKDDKLFFAMKVLQKERILGKNILKYALTERNVLSVMQH 409 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF+V+L AF+ LY ++ Y GG++ + + G + + K Y ++ILALE LH Sbjct: 410 PFIVSLKYAFQTKNKLYLVMDYCPGGDLDNLLFRKGRIPEPIAKIYICEIILALEALHNS 469 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGYSF 197 +V RD+KP N+++D +G+ + DFG K ++ T + CG+ YL PE++ G++ Sbjct: 470 NIVFRDLKPSNVVLDKDGHACITDFGLAKQGMQRGDITKSFCGSLAYLPPEMLNKTGHTQ 529 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 S+DW+ LG L +E+ G PP+++ + KL++ + K P+ S K+LLKGLL DP Sbjct: 530 SLDWYLLGVLMYELLEGMPPYYSDNKQKLFDNIRNAPLKMPKQASDAAKSLLKGLLSKDP 589 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 +R+GS G E+KSH +F ++W+ ++++KL+ P Sbjct: 590 IQRLGS--KGAEEVKSHPFFRDVNWEDVYNKKLLPP 623 >UniRef50_A2ELF7 Cluster: AGC family protein kinase; n=4; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 469 Score = 219 bits (535), Expect = 8e-56 Identities = 109/291 (37%), Positives = 175/291 (60%), Gaps = 7/291 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++DDF+I+ IG G YG+V L + K T +A+K V KS++++ +I E+ ++ Sbjct: 111 SMDDFNIISLIGKGFYGKVRLCQKKDTGDLYAIKSVHKSILIKTGRTCAVIAERNLMMKA 170 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 +FPF+V+L F+ YF L Y+ GG++ + + G K YA+Q+ LA+ YLH Sbjct: 171 KFPFLVSLHFTFQTRSKFYFGLEYVPGGDLKFHKSQVGKIPIFDAKLYAAQIGLAITYLH 230 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK--KKTWTLCGTPEYLAPEVITSKGYS 196 +V+RD+KPEN+L+D GY+KL DFG K + K T T CGTPEY++PE+I K Y Sbjct: 231 GIGIVYRDLKPENVLLDGQGYIKLVDFGLSKDINQVKTTRTFCGTPEYISPELILKKNYG 290 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 ++VD WALG L +E+ G PPF + NKLY+K+++ K P + P +++K LL D Sbjct: 291 YAVDEWALGVLMYEIIFGDPPFVDENENKLYDKIVLEEPKYPADADPNLVDIIKKLLVKD 350 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 P+KR ++KSH +F +D++ +++++ +VP ++ NF Sbjct: 351 PAKR-----PKFIDLKSHPFFADIDFKKVYNKEYKPSYVPKLTTRLSLENF 396 >UniRef50_A2D9C1 Cluster: AGC family protein kinase; n=4; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 474 Score = 219 bits (535), Expect = 8e-56 Identities = 113/293 (38%), Positives = 170/293 (58%), Gaps = 8/293 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 + DF ++K IG G YG+V L T A+K + KS ++++N +I E+ IL Q Sbjct: 106 MSDFRVLKVIGRGFYGKVTLCEHIATKEIVAIKSIHKSRLIQQNKVTTVISERNILAKAQ 165 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+V L AF+ Y L Y+ GGE+F ++Q+YG K Y ++++LAL +LH Sbjct: 166 HPFIVNLKFAFQSPSKFYLGLEYVPGGELFFHMQRYGNIRLDDCKIYIAEILLALNHLHS 225 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK--TWTLCGTPEYLAPEVITSKGYSF 197 V++RD+KPENIL+D+NG++KL DFG K L + T T CGT EYLAPEV+ + Y++ Sbjct: 226 LGVIYRDLKPENILLDANGHIKLTDFGLSKNLAHEVHTSTFCGTTEYLAPEVVNHQPYTY 285 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 SVDWWALG L++E+ G PF + K++ +L + P N + E + +K +L DP Sbjct: 286 SVDWWALGVLTYELLFGTTPFAHQNRAKMFRNILDNEPQFPPNFNQEAIDFIKAMLTKDP 345 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309 KR +IK +F L+W + +K+ FVP + + +NF PE Sbjct: 346 LKR-----PTFEQIKQMKFFQNLNWDDVLQKKIQPKFVPASDNSNEANNFDPE 393 >UniRef50_O42632 Cluster: Protein kinase C-like; n=14; Fungi|Rep: Protein kinase C-like - Cochliobolus heterostrophus (Drechslera maydis) Length = 1174 Score = 219 bits (534), Expect = 1e-55 Identities = 103/294 (35%), Positives = 174/294 (59%), Gaps = 7/294 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78 +D F+ + +G G +G+V L K T +A+KV++K ++E + + EK++ Sbjct: 846 LDHFNFLAVLGKGNFGKVMLAETKTTKQLYAIKVLKKEFIIENDEVESTRSEKRVFLIAN 905 Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + PF++ L F+ +YF++ YI+GG++ +IQ+ G F +FYA++V LAL+Y Sbjct: 906 KERHPFLLNLHACFQTETRVYFVMEYISGGDLMLHIQR-GQFGTKRAQFYAAEVCLALKY 964 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193 H V++RD+K +NI++ +G++K+ D+G CK T T CGTPE++APE++ K Sbjct: 965 FHENGVIYRDLKLDNIMLTLDGHIKVADYGLCKEEMWYGSTTSTFCGTPEFMAPEILLDK 1024 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y +VDWWA G L ++M PF D +++Y+ +L P +M + ++L+ LL Sbjct: 1025 KYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLL 1084 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +P R+GS EI SH +F ++W I+H+++ PF+P +SP DTSNF Sbjct: 1085 TREPEMRLGSGPTDAQEIMSHAFFRNINWDDIYHKRVQPPFIPQITSPTDTSNF 1138 >UniRef50_Q00078 Cluster: Protein kinase C-like; n=8; Eurotiomycetidae|Rep: Protein kinase C-like - Aspergillus niger Length = 1096 Score = 219 bits (534), Expect = 1e-55 Identities = 103/296 (34%), Positives = 176/296 (59%), Gaps = 7/296 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78 +D F+ + +G G +G+V L K T +A+KV++K ++E + + EK++ Sbjct: 768 LDHFNFLAVLGKGNFGKVMLAETKSTKRLYAIKVLKKEFIIENDEVESTKSEKRVFMIAN 827 Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + PF++ L F+ +YF++ YI+GG++ +IQ+ G F +FYA++V+LAL+Y Sbjct: 828 KERHPFLLNLHACFQTETRVYFVMEYISGGDLMLHIQR-GQFGLKRAQFYAAEVLLALKY 886 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193 H V++RD+K +NI++ +G++K+ D+G CK T T CGTPE++APE++ K Sbjct: 887 FHENGVIYRDLKLDNIMLTLDGHIKVADYGLCKENMWYGATTSTFCGTPEFMAPEILLDK 946 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y +VDWWA G L ++M PF D +++Y+ +L P +M + ++L+ LL Sbjct: 947 RYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLL 1006 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 +P R+GS E+ SH +F ++W I+H+++ PF+P SSP DTSNF + Sbjct: 1007 TREPELRLGSGPTDAQEVMSHAFFRNINWDDIYHKRVPPPFLPQISSPTDTSNFDQ 1062 >UniRef50_A7SL27 Cluster: Predicted protein; n=2; Eumetazoa|Rep: Predicted protein - Nematostella vectensis Length = 710 Score = 218 bits (533), Expect = 1e-55 Identities = 106/294 (36%), Positives = 180/294 (61%), Gaps = 5/294 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+ DF +K +G G++G+V L K T +A+K+++K V++ + + ++E+++L Sbjct: 379 TLKDFTFIKVLGKGSFGKVLLAERKGTDEVYAIKILKKESVLQDDDVECTMIERRVLALS 438 Query: 79 Q-FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 PF+ +L +F+ L+F++ Y+ GG++ IQK F ++ ++FYA++V+LAL++L Sbjct: 439 AGHPFLTSLHSSFQTVERLFFVMEYVNGGDLMFQIQKSRKFDENRSRFYAAEVVLALQFL 498 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKG 194 H V++RD+K +N+L+D++G++KL DFG CK K T T CGTP+Y+APE++ + Sbjct: 499 HQNGVIYRDLKLDNVLLDADGHIKLADFGMCKENMAPGKTTTTFCGTPDYIAPEILQEQP 558 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 Y FSVDWWALG L +EM AG PPF A + L+E +L P +S E ++LKG + Sbjct: 559 YGFSVDWWALGVLMYEMMAGQPPFEAENEEDLFESILHDDVLYPVWLSREAVSILKGFMT 618 Query: 255 VDPSKRIGSLKGGI-YEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 + KR+G I+ H +F ++++ + +++ PF P S D NF Sbjct: 619 KNYLKRLGCTPTSTESSIREHAFFRLINFEKLEARQINPPFKPKIRSRTDVGNF 672 >UniRef50_A6QRT1 Cluster: Serine/threonine-protein kinase psk1; n=1; Ajellomyces capsulatus NAm1|Rep: Serine/threonine-protein kinase psk1 - Ajellomyces capsulatus NAm1 Length = 1007 Score = 218 bits (533), Expect = 1e-55 Identities = 115/293 (39%), Positives = 175/293 (59%), Gaps = 7/293 (2%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEK-SVVVERNHAKHLILEKKILQCI-Q 79 DF+ + +G G YG V LVR +T +A K K S+ V R + E+ IL+ + + Sbjct: 645 DFEQLSCLGKGTYGTVLLVRHTMTGVLYAQKQFRKASLTVHRKLVEQTKTERAILESVNR 704 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PFVV L AF+D+ LY IL Y GGE+FT++ +FS+ + FY ++++LALE+LH Sbjct: 705 HPFVVKLYYAFQDHEKLYLILEYAQGGELFTHLAMERMFSEEVASFYMAELVLALEHLHN 764 Query: 140 -CEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195 VV+RD+KPEN L+D++G+L L DFG KV + + + GT EY+APEV+ K Y Sbjct: 765 NVGVVYRDLKPENCLLDADGHLLLTDFGLSKVAVDGQDRCNSSLGTVEYMAPEVVQGKPY 824 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 + DWW+LG L F++ G PPF A++ K+ EK++ P + P+ K+LL LL+ Sbjct: 825 GKACDWWSLGALGFDLLTGSPPFKANNHAKIQEKIVKQKLVLPYFLGPDAKDLLTRLLRK 884 Query: 256 DPSKRIG-SLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +P KR+G + I IK H +F +DW+++ ++L P P+ + P NF Sbjct: 885 EPHKRLGYHMPKDIQTIKKHRFFRKIDWKSLERRELEPPIKPLITDPALAENF 937 >UniRef50_Q16513 Cluster: Serine/threonine-protein kinase N2; n=42; Eumetazoa|Rep: Serine/threonine-protein kinase N2 - Homo sapiens (Human) Length = 984 Score = 218 bits (533), Expect = 1e-55 Identities = 103/296 (34%), Positives = 175/296 (59%), Gaps = 7/296 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78 + DF +G G +G+V L K T A+K ++K +V R+ L+ EK+I + + Sbjct: 654 LQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVN 713 Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + PF+V L F+ ++ F++ Y AGG++ +I +FS+ FYA+ V+L L+Y Sbjct: 714 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHT-DVFSEPRAVFYAACVVLGLQY 772 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193 LH ++V+RD+K +N+L+D+ G++K+ DFG CK +T T CGTPE+LAPEV+T Sbjct: 773 LHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTET 832 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y+ +VDWW LG L +EM G PF D ++++ ++ + P +S E ++++ LL Sbjct: 833 SYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLL 892 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 + +P +R+G+ + ++K H +F +DW A+ +K+ PF+P D SNF + Sbjct: 893 RRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDD 948 >UniRef50_UPI00015B57E6 Cluster: PREDICTED: similar to protein kinase c; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to protein kinase c - Nasonia vitripennis Length = 990 Score = 217 bits (531), Expect = 2e-55 Identities = 100/297 (33%), Positives = 178/297 (59%), Gaps = 7/297 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ-- 76 ++++F ++ +G G +G+V L + + T Y A+K ++K ++ R+ + L+ EK+I + Sbjct: 659 SLENFRLLSVLGRGHFGKVILSQYRNTGEYFAIKALKKGDIIARDEVESLLSEKRIFEVA 718 Query: 77 -CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135 + PF+V L F+ + ++ F++ Y AGG++ +I +F + FY++ V+L L+ Sbjct: 719 NATRHPFLVNLFACFQTDAHVCFVMEYAAGGDLMMHIHA-DVFGEPRAVFYSACVVLGLQ 777 Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITS 192 YLH +++RD+K +N+L+D+ GY+K+ DFG CK +T T CGTPE+LAPEV+T Sbjct: 778 YLHESRIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTE 837 Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252 Y+ +VDWW LG L FEM G PF D ++++ ++ + P +S E +++ L Sbjct: 838 TSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAIMRRL 897 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 L+ +P +R+GS + ++K +F + W + +++ PFVP+ S D SNF E Sbjct: 898 LRKNPDRRLGSSERDAEDVKKQAFFRHIAWDDLLLRRVKPPFVPVIHSVEDVSNFDE 954 >UniRef50_O17874 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 1012 Score = 217 bits (531), Expect = 2e-55 Identities = 111/321 (34%), Positives = 186/321 (57%), Gaps = 13/321 (4%) Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64 DF AP+ TV+ F ++ +G G +G+V L + T Y+A+KV++K ++ R+ Sbjct: 669 DFFASSDGAPL---TVEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDE 725 Query: 65 AKHLILEKKILQC---IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDS 121 + L++EK+I + + PF+V L+ F+ N +++F + Y GG++ +I +F + Sbjct: 726 VESLMVEKRIFEVSSRARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHD-DVFDEV 784 Query: 122 LTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK---KKTWTL 178 FYA+ V+L L++LH +++RDIK +N+L+D GY+K+ DFG CK KT T Sbjct: 785 RGCFYAACVVLGLDFLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTF 844 Query: 179 CGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCP 238 CGTPE+LAPEV++ Y+ ++DWW LG L FEM G PPF D ++++ ++ + P Sbjct: 845 CGTPEFLAPEVLSDSSYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYP 904 Query: 239 ENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGL--DWQAIFHQKLIAPFVP 296 +S E +++ LL+ P KR+G + +IK +F + +W + ++++ PF P Sbjct: 905 RYLSVESIAIMRRLLRKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQP 964 Query: 297 ICSSPGDTSNFP-EIPQPKLR 316 +P D SNF E Q K R Sbjct: 965 QIRNPEDVSNFDLEFTQEKAR 985 >UniRef50_UPI000150AAA4 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 1025 Score = 217 bits (530), Expect = 3e-55 Identities = 102/283 (36%), Positives = 173/283 (61%), Gaps = 4/283 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+ F I +G G++G+V+LV+ K Y+AMKV++KS +++ N K+ + E+ +L Sbjct: 692 TIHSFIIHSMLGKGSFGDVYLVQKKDNLQYYAMKVLQKSKMMKSNVIKYALTERNVLSLS 751 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L+ +F+ L+ IL + AGG+M +QK + S++ + Y S+++L+LEYLH Sbjct: 752 NHPFIVKLNYSFQTEEKLFLILDFAAGGDMGKLLQKVKVLSENDARIYLSEILLSLEYLH 811 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VL--KKKTWTLCGTPEYLAPEVITSKG 194 +++ RD+KP+NI+IDS G+ L DFG K VL + + CG+ YLAPE++ +G Sbjct: 812 KKDIIFRDLKPDNIVIDSEGHALLTDFGLSKEGVLDYTEGAKSFCGSIAYLAPEMLKRRG 871 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 + +VDW+ G + +EM G+PP++A+ L+ + P +S E K+LL LL+ Sbjct: 872 HGKAVDWYLFGVVMYEMLTGNPPYYANTKEDLFNNIQNAPLALPSYLSQEAKSLLTALLE 931 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPI 297 +P R+G + EIK+H +F +DW ++ +K+ AP V + Sbjct: 932 RNPEMRLGCGRNDANEIKNHPFFKSIDWDMVYERKIKAPEVQL 974 >UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative; n=2; Ostreococcus|Rep: CGMP-dependent protein kinase, putative - Ostreococcus tauri Length = 935 Score = 217 bits (529), Expect = 4e-55 Identities = 112/292 (38%), Positives = 175/292 (59%), Gaps = 5/292 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+D+ + V +G G++G V LV + TY A+K + K+ VV R +H+ EK+ + Sbjct: 620 TLDELETVGFLGVGSFGRVTLVSYQGE-TY-ALKEIGKAQVVSRGLVEHVWREKETMAQC 677 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQ-KYGIFSDSLTKFYASQVILALEYL 137 PF+V L + + ++ ++ + GGE+FTY+Q + ++ KFYA+ V+ A EYL Sbjct: 678 DSPFLVNLHRTYVNEKSIFMLMDKVLGGELFTYLQMRNAPLPEAHGKFYAACVVSAFEYL 737 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK--KTWTLCGTPEYLAPEVITSKGY 195 H +++RD+KPEN+LI +NGYLK+ DF F K L+K KT+TLCGTP+YLAPE + G+ Sbjct: 738 HDRNIIYRDLKPENLLISTNGYLKVTDFSFAKKLQKGQKTFTLCGTPQYLAPEQVQQVGH 797 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 + +VDWWALG L +E+ G PPF D Y+ + S+ +P ++++ GLL Sbjct: 798 NRAVDWWALGVLIYELVNGLPPFNQDDDYARYKAINDVSFHFSPKNAPAFRSVVSGLLLR 857 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 P+ R+G K G +IK H WF ++W A+ Q+ AP++P D +F Sbjct: 858 LPAGRLGMGKSGARDIKQHPWFADVNWSAMAQQRARAPYIPRVDDISDLRHF 909 >UniRef50_A2F0I9 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 405 Score = 217 bits (529), Expect = 4e-55 Identities = 114/296 (38%), Positives = 168/296 (56%), Gaps = 10/296 (3%) Query: 17 DKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ 76 D ++DDF+I+ IG G YG+V LV +K T AMK + K+ +++ +I E+ IL Sbjct: 82 DISMDDFNIISVIGRGFYGKVMLVENKYTKEICAMKTIHKARLIKEKKVHTVIAERNILV 141 Query: 77 CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + PF+V + AF++ LY + Y+ GGE+F +Q + Y ++V LALEY Sbjct: 142 KVNHPFIVNIKYAFQNETKLYIGMEYVPGGELFHMMQIVENLPMKAIRIYVAEVGLALEY 201 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-----KKKTWTLCGTPEYLAPEVIT 191 +H +V+RD+KPENILI + G++KL DFG KVL + T T CGT EYL PE+I Sbjct: 202 IHSLGIVYRDLKPENILITAEGHIKLTDFGLAKVLPEDEGEDTTKTFCGTNEYLPPEMIK 261 Query: 192 SKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKG 251 + Y +DWWALG L++E+ G PF +K+YEK+ P+N P + + Sbjct: 262 REYYGAMIDWWALGILTYELIYGDTPFVHKSKHKMYEKICNEEPHFPDNEDPNVVDFITK 321 Query: 252 LLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 LL+ DP KR LK ++K+H +FNGL ++ + K+ PF P S NF Sbjct: 322 LLKKDPKKR-AKLK----DLKNHPFFNGLKFEDVLALKVKPPFRPRIGSDRSVKNF 372 >UniRef50_Q16512 Cluster: Serine/threonine-protein kinase N1; n=26; Euteleostomi|Rep: Serine/threonine-protein kinase N1 - Homo sapiens (Human) Length = 942 Score = 217 bits (529), Expect = 4e-55 Identities = 105/297 (35%), Positives = 177/297 (59%), Gaps = 7/297 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T++DF + +G G +G+V L + + A+K ++K +V R+ + L+ EK+IL + Sbjct: 611 TLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAV 670 Query: 79 Q---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135 PF+V L F+ ++ F++ Y AGG++ +I +FS+ FY++ V+L L+ Sbjct: 671 TSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHS-DVFSEPRAIFYSACVVLGLQ 729 Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITS 192 +LH ++V+RD+K +N+L+D+ GY+K+ DFG CK +T T CGTPE+LAPEV+T Sbjct: 730 FLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTD 789 Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252 Y+ +VDWW LG L +EM G PF D ++++ ++ + P +S E +++ L Sbjct: 790 TSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRL 849 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 L+ +P +R+GS + ++K +F L W+A+ ++L PFVP S D SNF E Sbjct: 850 LRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDE 906 >UniRef50_O75582 Cluster: Ribosomal protein S6 kinase alpha-5; n=62; Eumetazoa|Rep: Ribosomal protein S6 kinase alpha-5 - Homo sapiens (Human) Length = 802 Score = 217 bits (529), Expect = 4e-55 Identities = 116/306 (37%), Positives = 186/306 (60%), Gaps = 17/306 (5%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKI----TFTYHAMKVVEKSVVVER-NHAKHLILEKKI 74 +++F+++K +G GAYG+VFLVR KI T +AMKV++K+ +V++ +H E+++ Sbjct: 46 IENFELLKVLGTGAYGKVFLVR-KISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQV 104 Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133 L+ I Q PF+VTL AF+ L+ IL YI GGE+FT++ + F++ + Y +++LA Sbjct: 105 LEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLA 164 Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEV 189 LE+LH +++RDIK ENIL+DSNG++ L DFG K ++ ++ CGT EY+AP++ Sbjct: 165 LEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDI 224 Query: 190 IT--SKGYSFSVDWWALGDLSFEMEAGHPPFFA----SDPNKLYEKVLVGSYKCPENMSP 243 + G+ +VDWW+LG L +E+ G PF + ++ ++L P+ MS Sbjct: 225 VRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSA 284 Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303 K+L++ LL DP KR+G EIK H +F ++W + +K+ APF P+ D Sbjct: 285 LAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELD 344 Query: 304 TSNFPE 309 SNF E Sbjct: 345 VSNFAE 350 Score = 124 bits (299), Expect = 3e-27 Identities = 85/268 (31%), Positives = 140/268 (52%), Gaps = 25/268 (9%) Query: 12 DAPIYDKTVDDFDIV-KAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLIL 70 D+P Y D D+ K +G G++ K + A+K++ K + E N K + Sbjct: 416 DSPFYQHY--DLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRM--EANTQKEITA 471 Query: 71 EKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQV 130 K C P +V L F D L+ + ++ + GGE+F I+K FS++ + ++ Sbjct: 472 LKL---CEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKL 528 Query: 131 ILALEYLHYCEVVHRDIKPENILI-DSNGYL--KLCDFGFCKVL---KKKTWTLCGTPEY 184 + A+ ++H VVHRD+KPEN+L D N L K+ DFGF ++ + T C T Y Sbjct: 529 VSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHY 588 Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPN-------KLYEKVLVGSY-- 235 APE++ GY S D W+LG + + M +G PF + D + ++ +K+ G + Sbjct: 589 AAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSF 648 Query: 236 --KCPENMSPECKNLLKGLLQVDPSKRI 261 + +N+S E K+L++GLL VDP+KR+ Sbjct: 649 EGEAWKNVSQEAKDLIQGLLTVDPNKRL 676 >UniRef50_A0DDH0 Cluster: Chromosome undetermined scaffold_46, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_46, whole genome shotgun sequence - Paramecium tetraurelia Length = 344 Score = 216 bits (528), Expect = 6e-55 Identities = 109/273 (39%), Positives = 179/273 (65%), Gaps = 10/273 (3%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 + DF +K +G GAYG VFLV K F +AMK + KS + +++ +H+ E++ILQC + Sbjct: 31 LQDFKKLKKLGQGAYGSVFLVEHKNEF--YAMKEIAKSRIQKKSTKQHIDSERQILQCTK 88 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 ++V L AF+D+ LY ++ Y+ GGE+F +I++ G F+ + KFY++Q+++AL LH Sbjct: 89 SKYLVELKYAFQDDRNLYMVVNYVKGGELFFHIREAGSFTLEICKFYSAQILMALLELHN 148 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITS-KGYS 196 +++RD+KPENIL+D G++ L DFG K L + T ++CGTPEYLAPE+ITS GYS Sbjct: 149 QNIIYRDLKPENILLDEQGHVVLTDFGLSKHLCDDELTKSMCGTPEYLAPEIITSNNGYS 208 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 F VD+++LG + +EM G PF++++ ++++ L P+++ +L+ GLL++D Sbjct: 209 FEVDYYSLGCIIYEMLNGKTPFYSTNKRQMFQDRLTRKVTWPDSIDETAISLVNGLLEID 268 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQK 289 P KR L+G EIK H +F +++ + + K Sbjct: 269 PLKR---LQGD--EIKKHKFFEDINFDELRNVK 296 >UniRef50_P24723 Cluster: Protein kinase C eta type; n=44; Eumetazoa|Rep: Protein kinase C eta type - Homo sapiens (Human) Length = 682 Score = 216 bits (528), Expect = 6e-55 Identities = 105/293 (35%), Positives = 176/293 (60%), Gaps = 5/293 (1%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +D+F+ ++ +G G++G+V L R K T +A+KV++K V++ + + + EK+IL + Sbjct: 351 IDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLAR 410 Query: 80 -FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+ L F+ L+F++ ++ GG++ +IQK F ++ +FYA+++I AL +LH Sbjct: 411 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLH 470 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGY 195 +++RD+K +N+L+D G+ KL DFG CK T T CGTP+Y+APE++ Y Sbjct: 471 DKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY 530 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 +VDWWA+G L +EM GH PF A + + L+E +L P + + +LK + Sbjct: 531 GPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTK 590 Query: 256 DPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +P+ R+GSL +GG + I H +F +DW + H+++ PF P S D SNF Sbjct: 591 NPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNF 643 >UniRef50_A0E8L1 Cluster: Chromosome undetermined scaffold_83, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_83, whole genome shotgun sequence - Paramecium tetraurelia Length = 569 Score = 216 bits (527), Expect = 8e-55 Identities = 98/280 (35%), Positives = 175/280 (62%), Gaps = 3/280 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++ DF I+K IG G + +V+LVR K+ ++AMK+V+K +++ A+ L E+ I+ I Sbjct: 158 SLKDFQILKCIGAGGFSKVYLVRSKMNGHFYAMKLVDKEFIIKYKKAELLQNERDIMAFI 217 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF + + +F+ ++ FIL + +GGE+F ++ S+ +FY ++ +++ YLH Sbjct: 218 HHPFTIQMLFSFESRNFVVFILEFCSGGELFYQLKTLKRMSEEQAQFYFVEICISMLYLH 277 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196 +++RDIKPENIL+D +G++++ DFG K+ + ++ CG+PEY+APE++ +G++ Sbjct: 278 QMGIMYRDIKPENILLDLDGHIRISDFGLSKLTTPDEFAYSFCGSPEYMAPEMLLKRGHT 337 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 VD + LG L +E+ G PPF++ + K+Y+ +L P+ +S E K+L+ GLL D Sbjct: 338 IQVDHYCLGALLYELVTGLPPFYSKNTQKIYDSILNEQVTFPQFLSQEIKDLMSGLLAKD 397 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 P KR+G ++GG+ EI H WF ++ I +++ P P Sbjct: 398 PHKRLG-VRGGVREILQHKWFKKVNLTDILMKRVTPPIRP 436 >UniRef50_A0BD03 Cluster: Chromosome undetermined scaffold_10, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_10, whole genome shotgun sequence - Paramecium tetraurelia Length = 363 Score = 216 bits (527), Expect = 8e-55 Identities = 115/311 (36%), Positives = 187/311 (60%), Gaps = 8/311 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVR-DKI-TFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77 + DF +K +G GAYG V LV DK ++AMK++EK + + + +H++ E+KIL+ Sbjct: 43 LSDFKKLKLLGKGAYGRVMLVEYDKNGKQKFYAMKILEKKNIRKESQIRHVLDERKILEK 102 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 FVV L AF+++ LYFI+ Y+ GG+++ +I+ F D +FYA++++ L++L Sbjct: 103 SNSNFVVKLRYAFQNHARLYFIVDYMEGGDLYYHIKSQPTFPDKFIRFYAAEILFGLQHL 162 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKG 194 H V++RD+KPENIL+ +G++KL DFG K+L K T CGT +YLAPEV+ ++G Sbjct: 163 HSLNVIYRDLKPENILLSQSGHIKLSDFGLSKILDDFNDKADTCCGTIDYLAPEVLGNEG 222 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 YSF+ D+++LG L +EM G PPF++ + + + + E + ++LL LL+ Sbjct: 223 YSFACDFYSLGCLIYEMYFGMPPFYSKNKRLMIQNRSIRLVPFSEQCPQDARDLLTRLLE 282 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE-IPQP 313 VDP KR+G + G +I +H +F LD Q + ++ AP + S D F E +PQ Sbjct: 283 VDPKKRLG--RKGAEQILNHAYFLELDLQKMKELQIQAPITIVNSDYIDLKMFREKVPQT 340 Query: 314 KLRKVSKYLYE 324 K + ++E Sbjct: 341 PQNKGTLKIFE 351 >UniRef50_Q8C050 Cluster: Ribosomal protein S6 kinase alpha-5; n=16; Coelomata|Rep: Ribosomal protein S6 kinase alpha-5 - Mus musculus (Mouse) Length = 863 Score = 216 bits (527), Expect = 8e-55 Identities = 116/306 (37%), Positives = 185/306 (60%), Gaps = 17/306 (5%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITF----TYHAMKVVEKSVVVER-NHAKHLILEKKI 74 +++F+++K +G GAYG+VFLVR KI+ +AMKV++K+ +V++ +H E+++ Sbjct: 45 IENFELLKVLGTGAYGKVFLVR-KISGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQV 103 Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133 L+ I Q PF+VTL AF+ L+ IL YI GGE+FT++ + F++ + Y +++LA Sbjct: 104 LEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLA 163 Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEV 189 LE+LH +++RDIK ENIL+DSNG++ L DFG K ++ ++ CGT EY+AP++ Sbjct: 164 LEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDI 223 Query: 190 IT--SKGYSFSVDWWALGDLSFEMEAGHPPFFA----SDPNKLYEKVLVGSYKCPENMSP 243 + G+ +VDWW+LG L +E+ G PF + ++ ++L P+ MS Sbjct: 224 VRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMST 283 Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303 K+LL+ LL DP KR+G EIK H +F + W + +K+ APF P+ D Sbjct: 284 VAKDLLQRLLMKDPKKRLGCGPRDAEEIKEHLFFEKIKWDDLAAKKVPAPFKPVIRDELD 343 Query: 304 TSNFPE 309 SNF E Sbjct: 344 VSNFAE 349 Score = 110 bits (264), Expect = 6e-23 Identities = 66/197 (33%), Positives = 112/197 (56%), Gaps = 19/197 (9%) Query: 84 VTLDVAFKDN--LYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 + L + DN L+ + ++ + GGE+F I++ FS++ + +++ A+ ++H Sbjct: 544 IVLFILLSDNGQLHTFLVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAVSHMHDVG 603 Query: 142 VVHRDIKPENILI-DSNGYL--KLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195 VVHRD+KPEN+L D N L K+ DFGF ++ + T C T Y APE++T GY Sbjct: 604 VVHRDLKPENLLFTDENDNLEIKVIDFGFARLKPPDNQPLKTPCFTLHYAAPELLTHNGY 663 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPN-------KLYEKVLVGSY----KCPENMSPE 244 S D W+LG + + M +G PF + D + ++ +K+ G + + +N+S E Sbjct: 664 DESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQE 723 Query: 245 CKNLLKGLLQVDPSKRI 261 K+L++GLL VDP+KR+ Sbjct: 724 AKDLIQGLLTVDPNKRL 740 >UniRef50_P83099 Cluster: Putative protein kinase C delta type homolog; n=3; Endopterygota|Rep: Putative protein kinase C delta type homolog - Drosophila melanogaster (Fruit fly) Length = 671 Score = 216 bits (527), Expect = 8e-55 Identities = 102/296 (34%), Positives = 176/296 (59%), Gaps = 4/296 (1%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC- 77 +VDDF + +G G++G+V L + T Y+A+K ++K VV+E + ++E+K+L Sbjct: 339 SVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALG 398 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 + P++ L F+ +L+F++ Y+ GG++ +IQ+ G FS+ +FY +++I L++L Sbjct: 399 TKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFL 458 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKG 194 H +++RD+K +N+L+D G++++ DFG CK+ L K + CGTP+Y+APE+I + Sbjct: 459 HKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEK 518 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 Y+ +VDWW+ G L +EM G PF D ++L+ + P +S E +LKGLL+ Sbjct: 519 YNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLE 578 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEI 310 D +KRIGS +I H +F +DW + +++ PF P P DT F + Sbjct: 579 KDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRV 634 >UniRef50_A1Z7T1 Cluster: CG2049-PC, isoform C; n=7; Fungi/Metazoa group|Rep: CG2049-PC, isoform C - Drosophila melanogaster (Fruit fly) Length = 1407 Score = 215 bits (526), Expect = 1e-54 Identities = 101/297 (34%), Positives = 178/297 (59%), Gaps = 7/297 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ-- 76 ++D+F ++ +G G +G+V L + + Y+A+K ++K ++ R+ + L+ EK+I + Sbjct: 1076 SMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVA 1135 Query: 77 -CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135 ++ PF+V L F+ ++ F++ Y AGG++ +I +F + FYA+ V+L L+ Sbjct: 1136 NAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHT-DVFLEPRAVFYAACVVLGLQ 1194 Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITS 192 YLH ++++RD+K +N+L+D+ GY+K+ DFG CK +T T CGTPE+LAPEV+T Sbjct: 1195 YLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTE 1254 Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252 Y+ +VDWW LG L FEM G PF D ++++ ++ + P +S E +++ L Sbjct: 1255 TSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRL 1314 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 L+ +P +R+GS + ++K +F + W + +K+ PFVP + D SNF E Sbjct: 1315 LRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDE 1371 >UniRef50_Q6AX33 Cluster: Microtubule-associated serine/threonine-protein kinase 3; n=9; Tetrapoda|Rep: Microtubule-associated serine/threonine-protein kinase 3 - Xenopus laevis (African clawed frog) Length = 1482 Score = 215 bits (526), Expect = 1e-54 Identities = 122/328 (37%), Positives = 185/328 (56%), Gaps = 27/328 (8%) Query: 3 KEDFNKKY-SDAPIYDKTVD-DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVV 60 +ED++ Y P K + DF+ +K I NGAYG V+LVR K T AMK + K ++ Sbjct: 377 QEDYHDPYIPSTPSRKKPCESDFETIKLISNGAYGAVYLVRHKETRQRFAMKKINKQNLI 436 Query: 61 ERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSD 120 RN + +E+ IL + PFVV++ +F+ +L ++ Y+ GG+ T ++ G Sbjct: 437 LRNQIHQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPV 496 Query: 121 SLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---------- 170 +++ Y ++ +LALEYLH +VHRD+KP+N+LI S G++KL DFG KV Sbjct: 497 DMSRMYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKVGLMNMTTNLY 556 Query: 171 ---LKKKT-----WTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASD 222 ++K T +CGTPEY+APEVI +GY VDWWA+G + +E G PFF Sbjct: 557 EGHIEKDTREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDT 616 Query: 223 PNKLYEKVLVGSYKCP---ENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNG 279 P +L+ +V+ P E + + ++L+ LL+ + +R+G+ GG E+K HT+F Sbjct: 617 PEELFGQVISDDIIWPGGEEALPADSQDLITRLLRQNSLERLGT--GGAQEVKQHTFFLS 674 Query: 280 LDWQAIFHQKLIAPFVPICSSPGDTSNF 307 LDW + QK A FVP + DTS F Sbjct: 675 LDWNGLLRQK--AEFVPQLEADDDTSYF 700 >UniRef50_Q62074 Cluster: Protein kinase C iota type; n=26; Eumetazoa|Rep: Protein kinase C iota type - Mus musculus (Mouse) Length = 586 Score = 215 bits (526), Expect = 1e-54 Identities = 113/319 (35%), Positives = 183/319 (57%), Gaps = 14/319 (4%) Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62 KE N + S + DFD+++ IG G+Y +V LVR K T +AMKVV+K +V + Sbjct: 224 KEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDD 283 Query: 63 NHAKHLILEKKIL-QCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDS 121 + EK + Q PF+V L F+ L+F++ Y+ GG++ ++Q+ + Sbjct: 284 EDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEE 343 Query: 122 LTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV-LK--KKTWTL 178 +FY++++ LAL YLH +++RD+K +N+L+DS G++KL D+G CK L+ T T Sbjct: 344 HARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTF 403 Query: 179 CGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPF----FASDPNK-----LYEK 229 CGTP Y+APE++ + Y FSVDWWALG L FEM AG PF + +P++ L++ Sbjct: 404 CGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQV 463 Query: 230 VLVGSYKCPENMSPECKNLLKGLLQVDPSKRIG-SLKGGIYEIKSHTWFNGLDWQAIFHQ 288 +L + P ++S + ++LK L DP +R+G + G +I+ H +F +DW + + Sbjct: 464 ILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQK 523 Query: 289 KLIAPFVPICSSPGDTSNF 307 +++ PF P S NF Sbjct: 524 QVVPPFKPNISGEFGLDNF 542 >UniRef50_P41743 Cluster: Protein kinase C iota type; n=97; Bilateria|Rep: Protein kinase C iota type - Homo sapiens (Human) Length = 587 Score = 215 bits (526), Expect = 1e-54 Identities = 113/319 (35%), Positives = 183/319 (57%), Gaps = 14/319 (4%) Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62 KE N + S + DFD+++ IG G+Y +V LVR K T +AMKVV+K +V + Sbjct: 225 KEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDD 284 Query: 63 NHAKHLILEKKIL-QCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDS 121 + EK + Q PF+V L F+ L+F++ Y+ GG++ ++Q+ + Sbjct: 285 EDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEE 344 Query: 122 LTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV-LK--KKTWTL 178 +FY++++ LAL YLH +++RD+K +N+L+DS G++KL D+G CK L+ T T Sbjct: 345 HARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTF 404 Query: 179 CGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPF----FASDPNK-----LYEK 229 CGTP Y+APE++ + Y FSVDWWALG L FEM AG PF + +P++ L++ Sbjct: 405 CGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQV 464 Query: 230 VLVGSYKCPENMSPECKNLLKGLLQVDPSKRIG-SLKGGIYEIKSHTWFNGLDWQAIFHQ 288 +L + P ++S + ++LK L DP +R+G + G +I+ H +F +DW + + Sbjct: 465 ILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQK 524 Query: 289 KLIAPFVPICSSPGDTSNF 307 +++ PF P S NF Sbjct: 525 QVVPPFKPNISGEFGLDNF 543 >UniRef50_Q21694 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 402 Score = 215 bits (525), Expect = 1e-54 Identities = 114/300 (38%), Positives = 175/300 (58%), Gaps = 12/300 (4%) Query: 17 DKTVDDFDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVV-ERNHAKHLILEK 72 D DF+ +K +G G YG+VF VR + T +AMKV+ K V +H E+ Sbjct: 43 DVAPKDFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARDER 102 Query: 73 KILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVIL 132 KIL+ I PF+ L AF+ N LY +L ++ GGE++T +++ + + +FY S++IL Sbjct: 103 KILETINSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIIL 162 Query: 133 ALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKK--KTWTLCGTPEYLAPEV 189 A+E+LH ++V+RD+KP+N++++ G++ L DFG CK LKK KT T CGT EY+APE+ Sbjct: 163 AIEHLHGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKGEKTLTFCGTHEYMAPEM 222 Query: 190 ITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLL 249 I G+ +VD WALG L ++M G PPF P + +L G + P +S K+L+ Sbjct: 223 IRKVGHDHAVDVWALGILMYDMFMGGPPFTGETPADKDKSILKGKVRLPPKLSASGKDLI 282 Query: 250 KGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 K +++ DP+ RI I +IK H +F +DW + PF P ++ D S+F E Sbjct: 283 KRIIKRDPTLRI-----TIPDIKEHEFFEEIDWDKLMAHDFEPPFKPTLANLEDVSHFDE 337 >UniRef50_A0BJU7 Cluster: Chromosome undetermined scaffold_110, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_110, whole genome shotgun sequence - Paramecium tetraurelia Length = 379 Score = 215 bits (525), Expect = 1e-54 Identities = 108/293 (36%), Positives = 175/293 (59%), Gaps = 10/293 (3%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 V +F ++K IG G +G+V LVR + + +AMK+V K + + ++ E+ IL+ I Sbjct: 56 VTNFKLLKTIGRGNFGKVLLVRKRNSGKIYAMKIVNKQDLQVKKQVEYARTERIILEKIN 115 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+ L AF+ LY+++ Y AGGE+F ++++ F ++ +FYA ++I+ALEYLH Sbjct: 116 HPFISKLHYAFQTQQKLYYVIDYCAGGELFFHLRRAYKFKENQVQFYAVEIIIALEYLHD 175 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK---KKTWTLCGTPEYLAPEVITSK--G 194 ++++RD+KPENIL+ S+G++KL DFG K++ K ++++ GTPEYLAPE+ + G Sbjct: 176 SKILYRDLKPENILLCSDGHIKLIDFGLSKIISNRDKPSFSIVGTPEYLAPEIYSDDKLG 235 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 + S DWW+LG L +EM G PF++ D ++ + S C +LL GLL Sbjct: 236 HDESCDWWSLGALLYEMLTGAAPFYSQDRTMMFRNRTEKQIEMKPWFSEACSSLLTGLLN 295 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +P +RI I +IK H +F+ +DW +++LI P +P S D F Sbjct: 296 NNPKQRI-----NIQQIKKHPFFSDIDWNQASNRQLIPPIIPELSDELDLRYF 343 >UniRef50_A4RL90 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 598 Score = 215 bits (525), Expect = 1e-54 Identities = 117/308 (37%), Positives = 182/308 (59%), Gaps = 8/308 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEK-SVVVERNHAKHLILEKKILQC 77 T D+F+ V+ +G GAYG V LV+ + T A K ++K S+ V + + + E+++L+ Sbjct: 221 TADEFEQVRCLGKGAYGTVILVKQRSTGRLFAQKQLKKASLTVSKKYVQQAKTERQVLET 280 Query: 78 I-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + + PFVV L AF+D+ LY IL Y GGE+F ++ +FS+ + FY +++LAL + Sbjct: 281 VNRHPFVVKLFYAFQDHEKLYLILEYGQGGELFHHLDTEKLFSEDVAAFYMGEMVLALFH 340 Query: 137 LHY-CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTW---TLCGTPEYLAPEVITS 192 LH VV+RD+KPEN L+D+ G+L L DFG KV + + GT EY+APE+I Sbjct: 341 LHQDLGVVYRDLKPENCLLDAEGHLLLTDFGLSKVAVDEDDHCNSFLGTIEYMAPEIILG 400 Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252 K YS +VDWWALG L ++ G+PPF ++ K+ + ++ P MS + K+LL L Sbjct: 401 KKYSKAVDWWALGALGHDLMTGNPPFRGANHAKIQDNIVKQKLMLPYFMSSDAKDLLTRL 460 Query: 253 LQVDPSKRIGS-LKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEI 310 L+ DP+KR+GS + + IK H +F +DW + +++ P P+ + P NF PE Sbjct: 461 LRKDPAKRLGSQMPKDLNLIKKHRFFRKIDWVKLSKREMEPPIRPLITDPELAENFAPEF 520 Query: 311 PQPKLRKV 318 + L V Sbjct: 521 TELSLSPV 528 >UniRef50_P36582 Cluster: Protein kinase C-like 1; n=2; Schizosaccharomyces pombe|Rep: Protein kinase C-like 1 - Schizosaccharomyces pombe (Fission yeast) Length = 988 Score = 215 bits (525), Expect = 1e-54 Identities = 103/316 (32%), Positives = 184/316 (58%), Gaps = 11/316 (3%) Query: 4 EDFNKKYSDAPIYDK----TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVV 59 +D N+ ++P +K T+DDF + +G G +G+V L K+ ++A+KV++K + Sbjct: 641 KDANRSVPESPRREKKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAI 700 Query: 60 VERNHAKHLILEKKILQCI---QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYG 116 ++ + L EK + + + PF++ L +F+ + +YF++ YI GG++ +IQ+ Sbjct: 701 LKNEELESLKTEKHVFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQQ 760 Query: 117 IFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKK 173 FS +FY ++V LAL+Y H + +RD+K +NIL+ +G++++ D+G CK +L Sbjct: 761 -FSVKRARFYGAEVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGN 819 Query: 174 KTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG 233 T T CGTPE++APE++ + YS VDWWA G L ++M G PF D ++++ +L Sbjct: 820 TTSTFCGTPEFMAPEILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSD 879 Query: 234 SYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 P NM + +LL+GLL DP++R+GS E+ +H +F + W ++++ Sbjct: 880 EPLFPINMPADAVSLLRGLLTRDPNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPS 939 Query: 294 FVPICSSPGDTSNFPE 309 + P+ + P D +NF E Sbjct: 940 YKPLINDPRDLNNFDE 955 >UniRef50_Q02156 Cluster: Protein kinase C epsilon type; n=34; Coelomata|Rep: Protein kinase C epsilon type - Homo sapiens (Human) Length = 737 Score = 215 bits (525), Expect = 1e-54 Identities = 116/324 (35%), Positives = 187/324 (57%), Gaps = 13/324 (4%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +D+F+ +K +G G++G+V L K +A+KV++K V+++ + + EK+IL + Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464 Query: 80 -FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 P++ L F+ L+F++ Y+ GG++ IQ+ F + ++FYA++V AL +LH Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKK-KTWTLCGTPEYLAPEVITSKGY 195 V++RD+K +NIL+D+ G+ KL DFG CK +L T T CGTP+Y+APE++ Y Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 SVDWWALG L +EM AG PPF A + + L+E +L P +S E ++LK + Sbjct: 585 GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTK 644 Query: 256 DPSKRIGSL--KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE---I 310 +P KR+G + + G IK H +F +DW + +K+ PF P + D +NF + Sbjct: 645 NPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTR 704 Query: 311 PQPKLRKVS----KYLYEEEFAEF 330 +P L V K + +EEF F Sbjct: 705 EEPVLTLVDEAIVKQINQEEFKGF 728 >UniRef50_Q22A18 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 355 Score = 215 bits (524), Expect = 2e-54 Identities = 104/298 (34%), Positives = 180/298 (60%), Gaps = 13/298 (4%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 ++DF + +G G++ +V LV+ K ++A+KV++KS + ++ H ++I E+ IL + Sbjct: 20 IEDFFMKAVLGKGSFAKVILVKKKDNGKFYAIKVLKKSKLEKQRHIDNVIAERNILVGVN 79 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY--- 136 PFV+ L +F+++ LYF+L + GGE+F + K F++ ++ +E+ Sbjct: 80 HPFVIQLHYSFQNSEKLYFVLEFCPGGELFNLLHKAQKFTEDYLDCACNRTSSLIEHHIQ 139 Query: 137 --LHYC-EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVI 190 + C + V +KPEN++ID +GY+++ DFG K +KT+++CGTPEYLAPE++ Sbjct: 140 RSIEMCGQRVTTYLKPENVMIDFDGYIRITDFGLSKNNISNHEKTYSVCGTPEYLAPEIL 199 Query: 191 TSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLK 250 T +G+ S DWW+LG L +E+ G PPF+ + +YE + + P+ +SP CK+L+ Sbjct: 200 TMQGHEKSADWWSLGALIYELLTGLPPFYNQNREVMYELIKNQNVNIPDYISPICKDLIY 259 Query: 251 GLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFP 308 LLQ +P R+G K G +EIK+H W +DW+ + ++ PF+PI + +NFP Sbjct: 260 RLLQKNPENRLG--KNGAFEIKNHPWLQDVDWEILLRKEYRPPFIPILDN--IVANFP 313 >UniRef50_A2EY79 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 716 Score = 215 bits (524), Expect = 2e-54 Identities = 113/305 (37%), Positives = 176/305 (57%), Gaps = 16/305 (5%) Query: 14 PIYDKTVDDFDIVKAIGNGAYGEVFLV-RDKITFTYHAMKVVEKSVVVERNHAKHLILEK 72 P + + +F VK I NGA+ VFL +DK+ A+KV+ + V + L+ EK Sbjct: 315 PKFCVNISEFKFVKRISNGAFARVFLATKDKLKSPV-AIKVIPRRNVRGKGSTNRLLTEK 373 Query: 73 KILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVIL 132 I+ P+ + + LY ++ Y+ GG++F+ ++K+G F + + + Y +Q++ Sbjct: 374 NIMLHFNSPYTIRFFYSTIGKHNLYMVMEYLPGGDLFSLLEKFGCFPEDVARNYTAQIVA 433 Query: 133 ALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFG--FCKVLKKKT----WTLCGTPEYLA 186 ALEYL V+HRD+KP+NIL+DS G+LKL DFG + V+ ++T T GTP+Y+A Sbjct: 434 ALEYLRQNNVIHRDLKPDNILLDSAGHLKLVDFGLSYFGVVGRQTDTHESTALGTPDYIA 493 Query: 187 PEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPE----NMS 242 PE+IT + +S+ D+W+LG + +E G PF + P +++ VL GS E N S Sbjct: 494 PEIITLENHSYQADYWSLGAMLYEFITGVAPFHDNTPQEIFSNVLCGSINFKELEEMNAS 553 Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302 +C + ++ LL DP KR+G+ I EIK H WFNG+DW + K+ PF+P Sbjct: 554 KDCIDFIQKLLVSDPKKRLGA--ESIDEIKHHPWFNGIDWDNL--DKMEPPFIPDVKDIF 609 Query: 303 DTSNF 307 DTSNF Sbjct: 610 DTSNF 614 >UniRef50_A2E5K8 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 450 Score = 215 bits (524), Expect = 2e-54 Identities = 105/280 (37%), Positives = 164/280 (58%), Gaps = 7/280 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++DDF ++ IGNG YG+V LV K T A+K + KS +++ + + E+ IL Sbjct: 105 SIDDFTPIRVIGNGYYGKVMLVTKKDTDEKFAIKSIHKSRLIQDKRSHSALAERNILLRA 164 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L AF+ YF L Y +GGE+F +QK G S+ +FY S+++LAL YLH Sbjct: 165 SHPFIVQLKFAFQTPSKFYFGLEYASGGELFARVQKSGGLSEKEVRFYLSEIVLALSYLH 224 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKT--WTLCGTPEYLAPEVITSKGYS 196 +++RD+KPENIL+D G++KL DFG K L + T CGT EY+APE+ + YS Sbjct: 225 SLGIIYRDLKPENILLDEEGHVKLTDFGLSKDLNATSGAQTFCGTYEYIAPEIAQHQPYS 284 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 + VDWWA+G L++EM PFF +++ EK++ P + E +L+ LL+ D Sbjct: 285 YEVDWWAIGILAYEMVMQVTPFFDKSQSRILEKIVNEDVSFPVEIPSELASLIAMLLRKD 344 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 P KR ++ H +F+G++W ++ +K+ ++P Sbjct: 345 PKKR-----AKYEDVIHHPFFSGVNWDDVYQRKIKPYYIP 379 >UniRef50_A0DZB2 Cluster: Chromosome undetermined scaffold_7, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_7, whole genome shotgun sequence - Paramecium tetraurelia Length = 379 Score = 215 bits (524), Expect = 2e-54 Identities = 107/300 (35%), Positives = 175/300 (58%), Gaps = 9/300 (3%) Query: 2 LKEDFNKKYSDAPIYDK-----TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEK 56 L ED + S P D+ ++ F +++ +G G+YG+V LV+ ++ +AMKV+ K Sbjct: 24 LVEDNEEVISQFPQQDEDGEKISLSHFIMLRNLGKGSYGKVMLVQHTVSLKLYAMKVLIK 83 Query: 57 SVVVERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYG 116 V KH+ E+K+L+ F+ L AF+ LY I+ ++ GGE+F +++ G Sbjct: 84 KSVKTLTQKKHVQTERKVLEITNHNFITKLHYAFQSQTKLYLIMEFVPGGELFYHLKLQG 143 Query: 117 IFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KK 173 ++ TKFYA+++++ L+YLH +++RD+KPENIL+DS G++KLCDFG K+ Sbjct: 144 RMTEKKTKFYAAEILIGLDYLHKQNIIYRDLKPENILLDSEGHIKLCDFGLSKICYGNDM 203 Query: 174 KTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG 233 T+CGT EY+APEVI + YS DWW G L +++ G PPF+ ++ E Sbjct: 204 SAKTVCGTIEYIAPEVIIGQVYSKCCDWWTYGALLYDLLTGKPPFYRLSRKQIIEYATEK 263 Query: 234 SYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 + P+ +S E +LLK LL+ +P +R+G LK EI H +F +D++ I +++ P Sbjct: 264 DIEIPQYLSEEATDLLKKLLKRNPRERLG-LKRDAQEIYEHPFFKDVDFKKIGRKEIAPP 322 >UniRef50_A2E8A4 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 687 Score = 214 bits (522), Expect = 3e-54 Identities = 109/303 (35%), Positives = 173/303 (57%), Gaps = 21/303 (6%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+ DF+ +K + GA+ VFL + K T +A+KV KS ++ +N K ++ EK IL Sbjct: 306 TIADFEFIKRVSRGAFARVFLAKKKSTGDIYAIKVQSKSNILNKNQGKRILAEKDILLHF 365 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 Q P+++ + Y ++ Y+ GG++++ + + + KFYA Q+ ALEYLH Sbjct: 366 QNPYIINFYYSILGTHNFYIVMEYLPGGDLYSLLHEVYSIDEESAKFYAYQIAKALEYLH 425 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFG--FCKVLKKK---------TWTLCGTPEYLAP 187 C ++HRD+KP+NIL+D+NG LKL DFG + V+ ++ + +L GTP Y+AP Sbjct: 426 KCGIIHRDLKPDNILVDANGNLKLTDFGLSYLGVVDRRINSDENIVQSDSLVGTPNYVAP 485 Query: 188 EVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYK-CPENMSPECK 246 E+I + +SF VD+W+LG + +E+ G PPF A +L +++G ++ + SPEC+ Sbjct: 486 EIILGQKHSFPVDYWSLGCVVYELLMGEPPFTADTEKELQNNIILGKFEHLDDEFSPECQ 545 Query: 247 NLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSN 306 + + LL VDPSKR+G+ G EI +H W G +Q PFVP S T Sbjct: 546 DFISRLLTVDPSKRLGA--NGAEEILNHPWLAG-------YQPSEKPFVPNIKSETSTEY 596 Query: 307 FPE 309 F + Sbjct: 597 FKQ 599 >UniRef50_A2DV83 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 740 Score = 213 bits (521), Expect = 4e-54 Identities = 113/298 (37%), Positives = 172/298 (57%), Gaps = 12/298 (4%) Query: 7 NKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAK 66 N ++ A T+ DF ++ I +GA+ +VFL T +A+KV KS + ++N K Sbjct: 306 NGTFAGAQSLQTTIADFTFIRKISSGAFAKVFLAIKTRTGDIYAIKVTPKSSLKQKNTFK 365 Query: 67 HLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFY 126 ++ EK IL PF+V + + LY ++ Y+ GG++++ + G ++ + Y Sbjct: 366 RVLTEKDILLQNSNPFIVDFYYSIIGDHNLYLVMEYLPGGDLYSLLNNIGSLDETAARIY 425 Query: 127 ASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFG------FCKVLKKKTWTLCG 180 +Q++ ALEYLH +VHRD+KP+NILI+ +G LKL DFG + + + + T+ G Sbjct: 426 TAQIVKALEYLHSHGIVHRDLKPDNILINISGKLKLTDFGLSLYGAYDRAIPDDSKTIVG 485 Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCP-- 238 TP+YLAPE+I S +SF+ D+W+LG + +E G PPF + + ++L G + Sbjct: 486 TPDYLAPEIILSSKHSFTADYWSLGCVIYEFLTGAPPFHMETEMETFAQILTGRFDIDPL 545 Query: 239 ENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 E+MS E +L+K LLQVDP KR+G GI EI H WF GLDW AI L FVP Sbjct: 546 EDMSDEVIDLIKHLLQVDPEKRLGF--NGIKEIMDHPWFAGLDWDAI--DDLEPVFVP 599 >UniRef50_A0DPW4 Cluster: Chromosome undetermined scaffold_6, whole genome shotgun sequence; n=6; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_6, whole genome shotgun sequence - Paramecium tetraurelia Length = 391 Score = 213 bits (521), Expect = 4e-54 Identities = 108/281 (38%), Positives = 177/281 (62%), Gaps = 9/281 (3%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 +DF + +G GA+G VF VR K T +AMK +EK + + + +LE+ +L+ + Sbjct: 61 EDFVKIDKLGYGAFGIVFKVRQKTTNKIYAMKQIEKEKIFKNKLQNNTVLERNVLKQSKH 120 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQ--KYGIFSDSLTKFYASQVILALEYLH 138 PF+V L AF+ N ++YF++ IAGGE + + K G+ +++ KF ++V+LALEYL+ Sbjct: 121 PFIVRLKYAFQTNSHIYFVMENIAGGEFYKILSQVKTGL-PENVVKFVGAEVVLALEYLN 179 Query: 139 -YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK---KKTWTLCGTPEYLAPEVITSKG 194 +V++RD+KPEN+L+ + G++KL DFG + + +K++T+ GT EYLAPE++ G Sbjct: 180 TKLKVIYRDLKPENLLLTTTGHVKLTDFGLATMRRENGEKSYTVAGTAEYLAPEIVNKSG 239 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFAS--DPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252 +S+ VD W LG L +EM G PF S D + +K++ PE MSP+ +L+K + Sbjct: 240 HSYEVDIWTLGILIYEMINGFTPFRDSNNDFKVISQKIIENQPIYPEKMSPQSVDLIKQI 299 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 LQ +PS+R+G G E+K H++FNG+ W + + K+ +P Sbjct: 300 LQTNPSERLGVKGDGYAELKRHSFFNGIIWDQMSNLKVTSP 340 >UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, whole genome shotgun sequence; n=8; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_42, whole genome shotgun sequence - Paramecium tetraurelia Length = 825 Score = 213 bits (521), Expect = 4e-54 Identities = 107/286 (37%), Positives = 173/286 (60%), Gaps = 11/286 (3%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 +V+D +K +G G +G V+LV+ K A+K V K+ ++E+N KH++ EK +L+ Sbjct: 493 SVEDLVYIKKLGEGQFGMVYLVKHKSINKVFALKSVSKASIIEQNLEKHILQEKTVLEQC 552 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 FPF++ FKD++ +YF++ YI G E+F I+ G+ + T+FY + +ILALEYLH Sbjct: 553 NFPFIMGFIRTFKDDISIYFLVEYIRGMELFDVIRDMGLLTKYDTQFYVATMILALEYLH 612 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITSKG 194 +V+RD+KPENI+++ GY+ L D G K L K +T+T+ GTP Y+APE+I KG Sbjct: 613 SKSIVYRDLKPENIMVNDAGYMYLIDLGTAKPLIKSRAYRTYTIIGTPHYMAPEIILGKG 672 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFF--ASDPNKLYEKVLVGSYKCPENM-SPECKNLLKG 251 YSF+VD W++G +E G P+ DP ++YE+++ K P + + K ++ Sbjct: 673 YSFNVDLWSMGICMYEFMCGGVPYAEEQDDPYEIYEEIMNTQLKFPTFIRDRQAKKFMEQ 732 Query: 252 LLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKL-IAPFVP 296 LL P R+GS +K++ WF+ D+ +F ++L P+VP Sbjct: 733 LLSKQPETRLGS---SFSALKANPWFDDFDFDKLFSRELQKVPYVP 775 >UniRef50_A6RHI7 Cluster: Serine/threonine-protein kinase Sgk2; n=1; Ajellomyces capsulatus NAm1|Rep: Serine/threonine-protein kinase Sgk2 - Ajellomyces capsulatus NAm1 Length = 459 Score = 213 bits (521), Expect = 4e-54 Identities = 100/251 (39%), Positives = 162/251 (64%), Gaps = 7/251 (2%) Query: 51 MKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFT 110 MK++ K+ ++ R+ H + E+ +L I PF+V L +F+ LY +L ++ GGE+F Sbjct: 1 MKILRKTHIISRSEVAHTLAERSVLSQINNPFIVPLKFSFQSPEKLYLVLAFVNGGELFH 60 Query: 111 YIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV 170 ++Q+ F + +FY +++I ALE LH ++++RD+KPENIL+D G++ LCDFG CK+ Sbjct: 61 HLQREQRFDINRARFYTAELICALECLHGFKIIYRDLKPENILLDYAGHIALCDFGLCKL 120 Query: 171 LKK---KTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLY 227 K +T T CGTPEYLAPE++ +GY+ +VDWW LG L +EM G PPF+ + N++Y Sbjct: 121 DMKDEDRTNTFCGTPEYLAPELLLGEGYTKAVDWWTLGVLLYEMLTGLPPFYDENTNEMY 180 Query: 228 EKVLVGSYKCP-ENMSP-ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAI 285 K+L P +++ P ++LL LL+ DP++R+G+ G EIK+H +F+ +DW+ + Sbjct: 181 RKILQEPLTFPSQDIVPGAARDLLTRLLEGDPNRRLGA--NGAAEIKAHHFFSNIDWRKL 238 Query: 286 FHQKLIAPFVP 296 +K F P Sbjct: 239 LQRKYEPSFRP 249 >UniRef50_Q9V3I5 Cluster: Chromosomal serine/threonine-protein kinase JIL-1; n=2; Coelomata|Rep: Chromosomal serine/threonine-protein kinase JIL-1 - Drosophila melanogaster (Fruit fly) Length = 1207 Score = 213 bits (521), Expect = 4e-54 Identities = 117/316 (37%), Positives = 188/316 (59%), Gaps = 20/316 (6%) Query: 8 KKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITF----TYHAMKVVEKSVVVE-R 62 K YSD + +++DF I++ +G GAYG VFLVR K+T +AMKV+ K VV+ R Sbjct: 249 KLYSDEAV---SLNDFKIIRVLGTGAYGRVFLVR-KLTRHDAGKLYAMKVLNKITVVQKR 304 Query: 63 NHAKHLILEKKILQCIQF-PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDS 121 A+H E+ +L+ IQ PF+V+L AF+ + LY +L + GGE+FT++ F +S Sbjct: 305 KTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEES 364 Query: 122 LTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWT 177 + Y ++V+LALE LH +++RDIK ENIL+D G++ L DFG K+L + + + Sbjct: 365 RVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHS 424 Query: 178 LCGTPEYLAPEVITS--KGYSFSVDWWALGDLSFEMEAGHPPFFASD----PNKLYEKVL 231 CGT EY+APE+I + G+ +VDWW++G L+FE+ G PF SD +++ ++ Sbjct: 425 FCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQ 484 Query: 232 VGSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLI 291 P + S ++ + +L+ +P +R+G EIK H +FNG++WQ + ++ Sbjct: 485 KEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRK 544 Query: 292 APFVPICSSPGDTSNF 307 AP+ P ++ D NF Sbjct: 545 APYKPTLTAEDDVQNF 560 Score = 70.1 bits (164), Expect = 7e-11 Identities = 67/261 (25%), Positives = 121/261 (46%), Gaps = 28/261 (10%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 DD ++ NGAYG V D T K++ S + LI L Sbjct: 621 DDLELGTRTSNGAYGTCHFVVDSSTDLVFLAKIIPLSKF-RPSEVDALI--SCALDTTNH 677 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 +V+ F++ + ++ Y++G E+ I+ + DS + + Q+++A+ ++H Sbjct: 678 KNIVSYHGTFREKCETWIVMEYLSGPELTASIR---MDEDSCREIFL-QLVMAVRHIHSK 733 Query: 141 EVVHRDIKPENILIDS--NGYLKLCDFG-FCKVLKKKTW--TLCGTPEYLAPEVITSKG- 194 +H D+KPENI+ ++ + +KL DFG C + K+W T +Y PE++ Sbjct: 734 HFIHGDLKPENIMFENREDRTVKLIDFGSACYNNRFKSWKDKPRYTLDYAPPEMLADANL 793 Query: 195 --YSFSVDWWALGDLSFEMEAGHPPF---------FASDPNKLYEKVLVGSYKCP----E 239 YS +VD + LG + M GH P+ A+ ++L +++ G++ E Sbjct: 794 VTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGTFNQRSMRWE 853 Query: 240 NMSPECKNLLKGLLQVDPSKR 260 + SP ++L+ LQ DP+ R Sbjct: 854 SASPAFRHLVSWCLQRDPADR 874 >UniRef50_Q584T1 Cluster: Rac serine-threonine kinase, putative; n=5; Trypanosoma|Rep: Rac serine-threonine kinase, putative - Trypanosoma brucei Length = 458 Score = 213 bits (520), Expect = 5e-54 Identities = 104/290 (35%), Positives = 175/290 (60%), Gaps = 17/290 (5%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 +++DF IG G++ V+ +K T +A+K +EK V+ N ++ E+ ILQ I Sbjct: 130 SLNDFQFAAKIGKGSFSSVYAATEKATGKTYAIKKMEKEVIERYNMIDNISAERLILQKI 189 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V+L AF+ LY ++ +++GGE+F +++ +F + KFY ++ LAL YLH Sbjct: 190 DHPFIVSLHYAFQTKGSLYLVMDFLSGGELFFHLESVSVFDEWRAKFYCGEIALALGYLH 249 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTWTLCGTPEYLAPEVITSKGYS 196 ++++RD+KPEN ++D++G++ L DFG K V +T CGTPEY+APE + K + Sbjct: 250 AQDIIYRDLKPENAVLDADGHVCLTDFGLAKMDVRDACNFTFCGTPEYIAPEFLLGKPHG 309 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLV----------GSYKCPENMSPECK 246 +VDWW+LG L +EM G PPF++ + + +Y+K+L GS P+ +S E + Sbjct: 310 KAVDWWSLGILLYEMLEGIPPFYSENVSAMYDKILSSELQFGDGEGGSNNMPQ-ISEEAQ 368 Query: 247 NLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 +LL+ LL +P R+ ++ E+K H +F LDW+ +F +++ PF P Sbjct: 369 DLLRRLLDRNPDTRLQDVE----ELKGHPFFRDLDWEKLFRREIEPPFRP 414 >UniRef50_A2ECT2 Cluster: AGC family protein kinase; n=3; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 437 Score = 213 bits (520), Expect = 5e-54 Identities = 108/290 (37%), Positives = 165/290 (56%), Gaps = 7/290 (2%) Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPF 82 F+I+ IG G YG+V LV+ K T A+K + KS ++++N +I E+ IL PF Sbjct: 110 FEIISVIGKGCYGKVRLVKSKSTGEVFAIKSIRKSKLIQQNRIHTVIAERNILSKANHPF 169 Query: 83 VVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEV 142 +V L AF+ Y L Y+ GGE++T I + G S K +Q+ +AL YLH + Sbjct: 170 IVALRFAFQTPAKFYLGLEYVPGGELYTRIHRDGYLSKMEYKMVIAQIAIALNYLHSIGI 229 Query: 143 VHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTWTLCGTPEYLAPEVITSKGYSFSVD 200 V+RDIKPENILI ++GY+KL DFG K + KT + CGTP+Y+APE I Y SVD Sbjct: 230 VYRDIKPENILIGADGYIKLADFGLAKDIITDNKTTSFCGTPKYIAPETIVGVPYDQSVD 289 Query: 201 WWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKR 260 WW+LG L++++ PF++ + + +Y +L + P++ SPE + + LL+ DP KR Sbjct: 290 WWSLGILTYQLIYHKFPFYSQNVDAVYRMILNKKVEFPDSASPEEIDFISILLEKDPKKR 349 Query: 261 IGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEI 310 G E+ H +F+ ++ I ++KL ++P P + F I Sbjct: 350 -----AGYNEVSQHPFFSEFTFEDILNKKLTPEYIPNLEEPTEVKYFDPI 394 >UniRef50_UPI00006CDDB0 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 880 Score = 213 bits (519), Expect = 7e-54 Identities = 106/283 (37%), Positives = 171/283 (60%), Gaps = 6/283 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+ FD++K IG G + EV+L R K + A+KV++K ++++ ++ EK + + Sbjct: 157 TLKHFDVLKKIGLGGFSEVYLARRKDNGQFVALKVIKKKTLIKKRRKLYVYNEKNTMIAL 216 Query: 79 QF-PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 + PF+V AF+ L F+L Y GGE+F ++ + F + +Q++ +E+L Sbjct: 217 KDNPFIVQFFFAFQTREKLIFVLEYCPGGELFYHLNQERRFKEEQAGILFAQILEGIEFL 276 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKG 194 H +++RD+KPENIL+D NGY+KL DFG KVLK K +T CG+ EY+APE+I KG Sbjct: 277 HSKNIIYRDLKPENILLDMNGYVKLADFGLSKVLKSKDQLNYTFCGSHEYMAPEMIQKKG 336 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC-PENMSPECKNLLKGLL 253 ++F+VD+++LG L +E+ AG PPF + + L EK L K P+ S + ++ +K L+ Sbjct: 337 HTFAVDYYSLGVLLYELVAGIPPFSSDNKTDLLEKALTKEVKFPPKQFSSQLQDFIKQLM 396 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 DP+KR+G+ K GI EI+ H W +++ I K P +P Sbjct: 397 IKDPTKRLGA-KSGISEIRKHPWCKKINFDKIRSLKFDPPIIP 438 >UniRef50_UPI00006CB393 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 538 Score = 213 bits (519), Expect = 7e-54 Identities = 93/177 (52%), Positives = 121/177 (68%) Query: 135 EYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKG 194 EYLH +V+RD+KPENILI S+GYLKL DFGF K +T+TLCGTPEYLAPE++ +KG Sbjct: 343 EYLHNKNIVYRDLKPENILIGSDGYLKLTDFGFAKYCDSRTYTLCGTPEYLAPEILLNKG 402 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 + VDWW LG L +EM AG PF DP +Y+K+L G K P N K+L+K LL Sbjct: 403 HGKPVDWWCLGILIYEMLAGIDPFNDEDPMAIYQKILKGKVKFPRNFDKNAKSLVKHLLV 462 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIP 311 D +KR G+LKGG+ +IK+H WF +DW A+FH+K+ + P+ GDTSN+ P Sbjct: 463 ADLTKRYGNLKGGVNDIKTHRWFADMDWDALFHKKIPPTYKPVVKGKGDTSNYSSYP 519 Score = 74.1 bits (174), Expect = 4e-12 Identities = 42/132 (31%), Positives = 71/132 (53%), Gaps = 17/132 (12%) Query: 27 KAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTL 86 ++I ++G V L + K T Y A+K+++K+ ++ H+I E IL I PF+V L Sbjct: 143 QSINRCSFGRVRLAKQKSTGEYVALKMLKKAEILRLKQVDHIISENTILSNINHPFLVNL 202 Query: 87 DVAF------------KDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILAL 134 + +D+ +LYF+L Y+AGGE+FTY++ G + FYA+QV Sbjct: 203 STFYLHQQVIKMIGFTQDDRFLYFVLEYVAGGELFTYLRNKGKLDNPEALFYAAQV---- 258 Query: 135 EYLHYCEVVHRD 146 Y+ C+++ D Sbjct: 259 -YIFVCDLLSYD 269 >UniRef50_Q4SG88 Cluster: Chromosome 17 SCAF14597, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 17 SCAF14597, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 754 Score = 213 bits (519), Expect = 7e-54 Identities = 108/296 (36%), Positives = 178/296 (60%), Gaps = 6/296 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 + +F +K +G G++G+V L K + +A+KV++K V+++ + + EK+IL + Sbjct: 425 LQNFVFIKVLGKGSFGKVMLAELKGSDEVYAVKVLKKDVILQDDDVDCTLTEKRILALAR 484 Query: 80 -FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 P++ L F+ L+F++ Y+ GG++ IQ+ F ++ ++FYA++V AL +LH Sbjct: 485 KHPYLTQLFCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEARSRFYAAEVTSALMFLH 544 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKK-KTWTLCGTPEYLAPEVITSKGY 195 V++RD+K +NIL+D++G+ KL DFG CK +L T T CGTP+Y+APE++ Y Sbjct: 545 RHGVIYRDLKLDNILLDADGHCKLADFGMCKEGILNGITTTTFCGTPDYIAPEILQELDY 604 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 SVDWWALG L +EM AG PPF A + + L+E +L P +S E ++LK + Sbjct: 605 GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTK 664 Query: 256 DPSKRIGSLKG-GIYE-IKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 P+KR+G + G+ E IK H +F +DW + +K+ PF P + D +NF + Sbjct: 665 SPNKRLGCVVAQGLEEAIKLHPFFREIDWTLLEQRKIRPPFKPRIKTKRDVNNFDQ 720 >UniRef50_A0E8C9 Cluster: Chromosome undetermined scaffold_82, whole genome shotgun sequence; n=14; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_82, whole genome shotgun sequence - Paramecium tetraurelia Length = 910 Score = 213 bits (519), Expect = 7e-54 Identities = 105/290 (36%), Positives = 176/290 (60%), Gaps = 8/290 (2%) Query: 14 PIYDKTVD--DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILE 71 PI K V DF +VK IG G + V++VR + ++A+K+++K +++ + E Sbjct: 392 PITTKRVGLKDFTLVKCIGVGGFSRVYMVRKRDNGKFYALKLIDKKFILDNQKEIIVQNE 451 Query: 72 KKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVI 131 + I+ ++ FV L AF+ Y+ F+L Y AGGE+F +++K ++ KFY ++ Sbjct: 452 RDIMVQMENQFVTPLHYAFETKYYIAFVLDYCAGGELFYHLRKLKRLNEQDAKFYFVEIC 511 Query: 132 LALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPE 188 + + YLH +V+RDIKPENIL+D G+L L DFG K ++ CG+PEY+APE Sbjct: 512 IGMAYLHSKNIVYRDIKPENILLDLQGHLLLSDFGLSKPDMTADDFAYSFCGSPEYMAPE 571 Query: 189 VITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPE--NMSPECK 246 ++ G+++ VD + LG L +E+ G PPF++ + ++Y +L + + P+ +SP K Sbjct: 572 MLMKTGHNYLVDCYCLGALLYELVTGLPPFYSHNTQEIYNSILTETVEFPQYVQISPVLK 631 Query: 247 NLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 L+ LLQ DP++R+G GGI EI +H WF+ +D++AI +++L P+ P Sbjct: 632 ELILQLLQKDPTERLG-YNGGIVEILTHQWFHDVDFEAIVNKQLKTPYKP 680 >UniRef50_P87253 Cluster: Protein kinase C-like; n=6; Pezizomycotina|Rep: Protein kinase C-like - Neurospora crassa Length = 1142 Score = 213 bits (519), Expect = 7e-54 Identities = 101/294 (34%), Positives = 173/294 (58%), Gaps = 7/294 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78 +D F+ + +G G +G+V L K + +A+KV++K ++E + + + EK++ Sbjct: 814 LDHFNFLAVLGKGNFGKVMLAETKKSRKLYAIKVLKKEFIIENDEVESIRSEKRVFLIAN 873 Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + PF+ L F+ +YF++ YI+GG++ +IQ+ G+F +FYA++V LAL+Y Sbjct: 874 RERHPFLTNLHACFQTETRVYFVMEYISGGDLMLHIQR-GMFGTKRAQFYAAEVCLALKY 932 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193 H V++RD+K +NIL+ +G++K+ D+G CK T T CGTPE++APE++ K Sbjct: 933 FHENGVIYRDLKLDNILLTLDGHIKIADYGLCKEDMWYGSTTSTFCGTPEFMAPEILLDK 992 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y +VDWWA G L ++M PF D +++Y+ +L P +M + ++L+ LL Sbjct: 993 KYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLL 1052 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +P +R+GS EI S +F ++W I+H+++ PF+P S DTSNF Sbjct: 1053 TREPDQRLGSGPTDAQEIMSQPFFRNINWDDIYHKRVQPPFLPQIKSATDTSNF 1106 >UniRef50_P34722 Cluster: Protein kinase C-like 1; n=3; Caenorhabditis|Rep: Protein kinase C-like 1 - Caenorhabditis elegans Length = 704 Score = 213 bits (519), Expect = 7e-54 Identities = 99/303 (32%), Positives = 181/303 (59%), Gaps = 5/303 (1%) Query: 12 DAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILE 71 D P+ + F+++K +G G++G+V LV K ++AMK ++K V++E + + +E Sbjct: 364 DGPVKKFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIE 423 Query: 72 KKIL-QCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQV 130 +++L Q PF+ L +F+ N YL+F++ Y+ GG++ +IQ+ F ++ T+FYA ++ Sbjct: 424 RRVLILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEI 483 Query: 131 ILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK----TWTLCGTPEYLA 186 ++AL++LH +++RD+K +N+L+D +G++KL DFG K + T CGTP+Y++ Sbjct: 484 VVALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYIS 543 Query: 187 PEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECK 246 PE+I + Y+ +VD+W+ G L +EM G PF ++L++ +L P+ +S E Sbjct: 544 PEIIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAA 603 Query: 247 NLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSN 306 L L +P+ R+G + I+ H +F G+DW+ ++++ PF P S D SN Sbjct: 604 KCLSALFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSNSDASN 663 Query: 307 FPE 309 F + Sbjct: 664 FDD 666 >UniRef50_Q23PX4 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 1706 Score = 212 bits (518), Expect = 9e-54 Identities = 103/296 (34%), Positives = 181/296 (61%), Gaps = 9/296 (3%) Query: 5 DFNKKYSDAPIYDKTV--DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62 DFN D + V + F +++ IG G + V+LV+ K T A+K+++K ++E Sbjct: 944 DFNLDTIDNTFQYREVGLESFHLIRCIGLGGFSRVYLVQKKDTGKMFALKLIDKKFIIEN 1003 Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122 + E+ I+ I PF++ L+ +F+ YL F + Y AGGE+F ++++ S+ + Sbjct: 1004 KKEVIVQNERNIMASIAHPFLLKLEYSFESKSYLGFCMEYCAGGELFYHLRRIKRMSEEM 1063 Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLC 179 +FY ++ L ++YLH +++RDIKPENIL+D +G++++ DFG K + + ++ C Sbjct: 1064 ARFYFVEICLGIDYLHKRHIIYRDIKPENILLDLDGHVRIGDFGLSKPDMDINEHAYSFC 1123 Query: 180 GTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPE 239 G+PEY+APE++ G++++VD++ LG L +E+ G PPF++ D + +Y+++L P+ Sbjct: 1124 GSPEYMAPEMLMKVGHTYTVDFYCLGALLYELVTGLPPFYSHDTDAIYQRILSEDLDFPD 1183 Query: 240 N--MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 + +S E KNLLKGLL P R+G +K GI +I +H+WF + + +KLI P Sbjct: 1184 HVELSIELKNLLKGLLAKHPQNRLG-IKNGIRDILAHSWFKPIKIGDVL-EKLIEP 1237 >UniRef50_A2DW86 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 423 Score = 212 bits (518), Expect = 9e-54 Identities = 107/291 (36%), Positives = 165/291 (56%), Gaps = 7/291 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+DDFD++ +G G YG+V L K T A+K V K+ +V + E+ +L Sbjct: 103 TMDDFDVISVLGRGFYGKVMLCHKKNTNDIFAIKTVHKNRLVSAKKVHTIFTERNVLMKA 162 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 Q PF+V+L AF+ + +Y L Y GGE+F ++QK+G F + Y +++ LAL++LH Sbjct: 163 QHPFIVSLKFAFQTDTKVYLGLEYAPGGELFYHLQKFGSFPIDDVRIYIAEMALALDFLH 222 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196 V++RDIKPENIL+D+ G++KL DFG K L + T T CGT EY+APEV+ Y Sbjct: 223 KHGVIYRDIKPENILLDAQGHVKLTDFGLAKDLTDESSTTTFCGTFEYMAPEVVARSSYG 282 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 ++DWWALG L++E+ GH PF + + L+ + K P + + LL D Sbjct: 283 PAIDWWALGILTYELLNGHSPFQSDNRALLFMSIRTQPPKFPARTDRNTIDFISNLLNKD 342 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 P L+ G+ +I++H +FNG+++ + +K FVP + NF Sbjct: 343 P-----ELRYGMDQIRTHPFFNGMNFDDVLEKKYKPSFVPTIPNDVAALNF 388 >UniRef50_A0DTA2 Cluster: Chromosome undetermined scaffold_62, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_62, whole genome shotgun sequence - Paramecium tetraurelia Length = 389 Score = 212 bits (518), Expect = 9e-54 Identities = 111/304 (36%), Positives = 178/304 (58%), Gaps = 7/304 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 ++DF ++ +G GA+G+V+ V+ K +A+K + K ++ + + +LEK +L+ + Sbjct: 60 LEDFIMLATVGKGAFGKVYKVKKKDNQKIYAIKCINKKLIFDSKLESNALLEKDVLKQSK 119 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL-H 138 PF+V L +F+ LY ++ YI GGE F + K +S+ F A++V+LALEYL + Sbjct: 120 HPFIVQLKYSFQTPTKLYLVMEYINGGEFFKILTKTKGLPESIVAFVAAEVVLALEYLNN 179 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK---KTWTLCGTPEYLAPEVITSKGY 195 +V++RD+KPENIL+ + G++KL DFG + K K +TL GTPEYLAPE+I KG+ Sbjct: 180 QLKVIYRDLKPENILLTTTGHVKLTDFGLATLRKDENVKNYTLAGTPEYLAPEIINKKGH 239 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPN--KLYEKVLVGSYKCPENMSPECKNLLKGLL 253 SF VD W LG L +EM G+PPF D N K+ +L MS E NL++ LL Sbjct: 240 SFEVDLWTLGILIYEMINGYPPFTVPDRNTQKILSLILQNQPAYTPIMSDEAVNLVQRLL 299 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQP 313 + +P +RIG+ + G EIK H +F + W +++ + +P S +PQ Sbjct: 300 KANPKERIGA-EMGYQEIKYHPFFAKIKWSELYNLNVKSPLKTFAEQNASRSEGFRMPQI 358 Query: 314 KLRK 317 ++++ Sbjct: 359 QIQE 362 >UniRef50_A0BPA1 Cluster: Chromosome undetermined scaffold_12, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_12, whole genome shotgun sequence - Paramecium tetraurelia Length = 767 Score = 212 bits (518), Expect = 9e-54 Identities = 102/275 (37%), Positives = 171/275 (62%), Gaps = 6/275 (2%) Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPF 82 F ++ IG G++GEV+LV+ +AMKV+ KS +++ N ++ + E+ +L PF Sbjct: 454 FQVIGLIGKGSFGEVYLVQKNNQL--YAMKVLHKSRIMKHNLTRYALTERNVLSITSHPF 511 Query: 83 VVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEV 142 +V L AF+ L+ IL Y GG++ +QK +S+ K Y +++LALE LH ++ Sbjct: 512 IVKLRFAFQTQDKLFMILDYCPGGDLGEVLQKQKRLPESIVKNYLCEIVLALEDLHKRDI 571 Query: 143 VHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW--TLCGTPEYLAPEVITSKGYSFS 198 + RD+KP+NI++D+ G+ L DFG K +L+ T + CG+ YLAPE++ G+ + Sbjct: 572 IFRDLKPDNIVLDAEGHALLTDFGLSKEGILEPNTGARSFCGSVAYLAPEMLKRSGHGKA 631 Query: 199 VDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPS 258 VDW+ LG + +E+ G PP++A++ +L+ + K P +S E KNLLK LLQ +P+ Sbjct: 632 VDWYLLGVVMYELLVGLPPYYANNREELFYNIENAQLKIPSYISNEAKNLLKALLQRNPA 691 Query: 259 KRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 KR+GS KG EIK+H +F ++W+ +++++L P Sbjct: 692 KRLGSGKGDSEEIKAHQYFQDVNWEVVYNRELAMP 726 >UniRef50_Q86ZV2 Cluster: Protein kinase C; n=1; Pichia pastoris|Rep: Protein kinase C - Pichia pastoris (Yeast) Length = 1035 Score = 212 bits (518), Expect = 9e-54 Identities = 111/323 (34%), Positives = 180/323 (55%), Gaps = 13/323 (4%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78 +DDF + +G G +G+V L T A+KV++K +++ + EK++ Sbjct: 706 LDDFRFIAVLGKGNFGKVMLAESIHTGQLCAIKVLKKDFIIKNDEVASTKSEKRVFIIAN 765 Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + PF++ L F+ +YF++ Y++GG++ + Q+ FS S KFYA++V+LAL+Y Sbjct: 766 RGKHPFLLNLHQCFQTENRIYFVMEYVSGGDLMWHAQQR-TFSPSRAKFYAAEVLLALQY 824 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193 H VV+RD+K +NIL+ ++G++KL D+G CK T T CGTPE++APE++ + Sbjct: 825 FHENGVVYRDLKLDNILLTADGHIKLADYGLCKEEMWYGSTTATFCGTPEFMAPEILKEQ 884 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y +VDWWA G L ++M G PF D ++++ +L + P M E ++L+ LL Sbjct: 885 KYDKAVDWWAFGVLLYQMMLGKSPFKGEDEDEVFNSILTDEPRYPIQMDRESVDILQQLL 944 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFP---EI 310 DP KR+G+ + EIK H +F+G++W I K+ P +P D SNF Sbjct: 945 TKDPYKRLGASEEDAEEIKRHPYFHGINWDDIMQCKVPPPLIPTIKDRHDVSNFDVEFTT 1004 Query: 311 PQPKLRKVSKYL---YEEEFAEF 330 PKL V+ L +E+F F Sbjct: 1005 EAPKLTPVNSVLSLSMQEQFRGF 1027 >UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14; Apicomplexa|Rep: CGMP-dependent protein kinase - Plasmodium falciparum Length = 853 Score = 212 bits (517), Expect = 1e-53 Identities = 111/310 (35%), Positives = 172/310 (55%), Gaps = 3/310 (0%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +D+ + + IG G +G V LV K T +A+K V K ++ N ++ LE++I Sbjct: 538 MDELETERIIGRGTFGTVKLVHHKPTKIRYALKCVSKRSIINLNQQNNIKLEREITAEND 597 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF++ L FKD+ Y YF+ + GGE++ I+K G+ S S +FY +ILA+EYLH Sbjct: 598 HPFIIRLVRTFKDSKYFYFLTELVTGGELYDAIRKLGLLSKSQAQFYLGSIILAIEYLHE 657 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSV 199 +V+RD+KPENIL+D GY+KL DFG K ++ + +TL GTP Y+APEVI KGY +V Sbjct: 658 RNIVYRDLKPENILLDKQGYVKLIDFGCAKKVQGRAYTLVGTPHYMAPEVILGKGYGCTV 717 Query: 200 DWWALGDLSFEMEAGHPPFFASDPNKL--YEKVLVGSYKCPENMS-PECKNLLKGLLQVD 256 D WALG +E G PF + ++L + +L G P+ ++ + NL+K LL Sbjct: 718 DIWALGICLYEFICGPLPFGNDEEDQLEIFRDILTGQLTFPDYVTDTDSINLMKRLLCRL 777 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPKLR 316 P RIG G +IK H +F+ +W + + L P V + + + +I + Sbjct: 778 PQGRIGCSINGFKDIKDHPFFSNFNWDKLAGRLLDPPLVSKSETYAEDIDIKQIEEEDAE 837 Query: 317 KVSKYLYEEE 326 + L +E+ Sbjct: 838 DDEEPLNDED 847 >UniRef50_Q04759 Cluster: Protein kinase C theta type; n=20; Euteleostomi|Rep: Protein kinase C theta type - Homo sapiens (Human) Length = 706 Score = 212 bits (517), Expect = 1e-53 Identities = 108/307 (35%), Positives = 182/307 (59%), Gaps = 9/307 (2%) Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64 + NK+ I K ++DF + K +G G++G+VFL K T + A+K ++K VV+ + Sbjct: 363 ELNKERPSLQIKLK-IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDD 421 Query: 65 AKHLILEKKILQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLT 123 + ++EK++L + PF+ + F+ L+F++ Y+ GG++ +IQ F S Sbjct: 422 VECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRA 481 Query: 124 KFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCG 180 FYA+++IL L++LH +V+RD+K +NIL+D +G++K+ DFG CK + KT T CG Sbjct: 482 TFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCG 541 Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240 TP+Y+APE++ + Y+ SVDWW+ G L +EM G PF D +L+ + + + P Sbjct: 542 TPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW 601 Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300 + E K+LL L +P KR+G ++G +I+ H F ++W+ + +++ PF P S Sbjct: 602 LEKEAKDLLVKLFVREPEKRLG-VRG---DIRQHPLFREINWEELERKEIDPPFRPKVKS 657 Query: 301 PGDTSNF 307 P D SNF Sbjct: 658 PFDCSNF 664 >UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2; Eimeria|Rep: CGMP-dependent protein kinase - Eimeria maxima Length = 1007 Score = 211 bits (516), Expect = 2e-53 Identities = 105/278 (37%), Positives = 159/278 (57%), Gaps = 3/278 (1%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 D +V+ +G G +G V LV+ T +A+K V + VV N H+ LE++I+ P Sbjct: 696 DLQVVRVVGRGTFGTVKLVQHIPTKIRYALKCVSRKSVVALNQQDHIRLEREIMAENDHP 755 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F++ L F+D +LYF+ + GGE++ I+K G+ +FY + ++LA+EYLH Sbjct: 756 FIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHERN 815 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSVDW 201 + +RD+KPENIL+DS GY+KL DFG K ++ + +TL GTP Y+APEVI KGY+ + D Sbjct: 816 IAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTADT 875 Query: 202 WALGDLSFEMEAGHPPF--FASDPNKLYEKVLVGSYKCPENMS-PECKNLLKGLLQVDPS 258 WA G +E G PF A D +++ +L G P ++ + NL+K LL P Sbjct: 876 WAFGVCLYEFMCGPLPFGNDAEDQLEIFRDILAGKLMFPHYVTDQDAINLMKRLLCRLPE 935 Query: 259 KRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 RIG G +IK H +F+ DW + + L P +P Sbjct: 936 VRIGCSINGYKDIKEHAFFSDFDWDRLAGRDLSPPLLP 973 >UniRef50_A0EIN6 Cluster: Chromosome undetermined scaffold_99, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_99, whole genome shotgun sequence - Paramecium tetraurelia Length = 603 Score = 211 bits (516), Expect = 2e-53 Identities = 103/316 (32%), Positives = 186/316 (58%), Gaps = 7/316 (2%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 DDF ++K IG G + V+LVR K + AMK+++KS +++ N + EK I+ + Sbjct: 180 DDFTLIKCIGVGGFSRVYLVRQKRNGQFFAMKIIDKSFIIKNNKESMINNEKWIMSNLDS 239 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 F+ L +F+ YL F++ Y GGE+F +++K G S+ + K Y Q+ LA+ YLH Sbjct: 240 QFLTRLHCSFETKYYLVFVMDYCHGGELFFHLRKMGTLSEEVAKQYFGQLCLAIHYLHEQ 299 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197 V++RD+KPENIL+D +GY+KL DFG K K+T++ CG+PEY++PE+++ +G++ Sbjct: 300 NVIYRDLKPENILLDIDGYIKLSDFGLSKPNISRDKQTYSFCGSPEYMSPEMVSKRGHNQ 359 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--MSPECKNLLKGLLQV 255 +D ++LG + +E G+PP++ + + + PE+ +S + KNLL LL Sbjct: 360 LLDCYSLGAVLYEFIYGYPPYYDQQLQNILNSIQYDKLEFPEHIKISDQLKNLLLNLLTK 419 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP-ICSSPGDTSNFPEIPQPK 314 D ++R+G + GI ++ +H W + ++ A++ ++L + P + + + F + + Sbjct: 420 DQNERLGRM-NGIEDVLNHKWLSNFNYTALYKKQLNIQYKPQPLQTNYNVAEFSKGDREF 478 Query: 315 LRKVSKYLYEEEFAEF 330 +K+ LY E+ +F Sbjct: 479 QQKLQDNLYREQKTKF 494 >UniRef50_A0BN99 Cluster: Chromosome undetermined scaffold_118, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_118, whole genome shotgun sequence - Paramecium tetraurelia Length = 562 Score = 211 bits (516), Expect = 2e-53 Identities = 101/293 (34%), Positives = 180/293 (61%), Gaps = 6/293 (2%) Query: 10 YSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLI 69 YS+ +++D+DI+K IG G + V+LVR + ++AMK+++K+ +++ N + Sbjct: 147 YSNPVGQQMSIEDYDILKCIGVGGFSRVYLVRKRDNGLFYAMKLIDKNFILKSNKEIIIC 206 Query: 70 LEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQ 129 EK +++ + P++ L +F+ YL F++ Y AGGE+F +++K+ S+ L K Y Q Sbjct: 207 NEKYVMEQLNSPYLAKLFYSFETKFYLVFVMEYCAGGELFYHLRKWKRLSEPLAKQYFVQ 266 Query: 130 VILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLA 186 V LA+ LH +V+RDIKPENIL+D +GY++L DFG K + ++ CG+PEY++ Sbjct: 267 VCLAINELHKFGIVYRDIKPENILLDLDGYIRLSDFGLSKPNMNRDETAYSFCGSPEYMS 326 Query: 187 PEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCP--ENMSPE 244 PE++ +G+++ VD + LG L +E G PPF+ + +++Y +L + P ++++P+ Sbjct: 327 PEMLKREGHNYMVDIYCLGALLYEFIFGSPPFYCRNIDQIYNSILNDKLQFPPFKDINPD 386 Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPI 297 K+L+ LL DP+KR+G+ + GI I H WF D + + +K + P+ Sbjct: 387 LKDLISKLLIKDPAKRLGA-QNGIKSILQHKWFQDCDIEGLVKRKCEISYRPM 438 >UniRef50_Q8TFJ3 Cluster: Protein kinase A catalytic subunit; n=1; Mucor racemosus|Rep: Protein kinase A catalytic subunit - Rhizomucor racemosus (Mucor circinelloides f. lusitanicus) Length = 605 Score = 211 bits (516), Expect = 2e-53 Identities = 98/284 (34%), Positives = 174/284 (61%), Gaps = 9/284 (3%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQ 79 +DF IV+ IG G+ G+V+ V + + +AMKV+ K +++ N E+ +L Q + Sbjct: 245 EDFRIVRMIGQGSVGKVYEVIKRDSGRTYAMKVLSKRLLLAENEVDTAFNERNVLVQSLS 304 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+ L +F+ +L+ ++ Y GGE+F ++++ S+ +F+A++++ A + +H Sbjct: 305 SPFIANLKYSFQTTNHLFLVMDYFPGGELFDFLERERCLSEKRCQFFAAEIVCAFDNIHA 364 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP-----EYLAPEVITSKG 194 +V+R++KPE+IL+D++G++ L DFG CK LK K + G P EYLAPE++ K Sbjct: 365 RNIVYRNLKPESILLDAHGHIALTDFGLCKQLKNKMDLIQGVPQVITQEYLAPEMVMQKP 424 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--MSPECKNLLKGL 252 Y + DWW+LG L FE+ G PPF + + +L+ ++L K P ++ E K+ + L Sbjct: 425 YGMAADWWSLGVLMFELLTGSPPFHSVEQGELFRQILEAPIKFPAGGCITEEAKDFICQL 484 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 L+ DP+KR+GS G + ++K+H +F L+W ++ +++ PFVP Sbjct: 485 LERDPAKRLGS-HGDVAQVKAHPFFKDLNWDVVYKKQMQLPFVP 527 >UniRef50_A1CKA9 Cluster: Serine/threonine protein kinase, putative; n=13; Pezizomycotina|Rep: Serine/threonine protein kinase, putative - Aspergillus clavatus Length = 599 Score = 211 bits (516), Expect = 2e-53 Identities = 109/296 (36%), Positives = 174/296 (58%), Gaps = 7/296 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEK-SVVVERNHAKHLILEKKILQC 77 T DF+ + +G G++G V LVR +T +A K K S+ V + + E+ IL+ Sbjct: 233 TTSDFEPLLCLGKGSFGTVLLVRHALTGKLYAQKQFRKASLTVHKKLVEQTKTERAILES 292 Query: 78 I-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + + PFVV L AF+D+ LY IL Y GGE+F ++ +F + FY ++++LALE+ Sbjct: 293 VNRHPFVVKLFYAFQDHEKLYLILEYAQGGELFHHLAIERMFDEDTAAFYMAEMVLALEH 352 Query: 137 LHY-CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK---KTWTLCGTPEYLAPEVITS 192 LH V++RD+KPEN L+D G+L L DFG K+ + + GT EY+APEVI Sbjct: 353 LHQNVGVIYRDLKPENCLLDHEGHLLLTDFGLSKIAVNDDDRCNSSLGTIEYMAPEVIQG 412 Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252 K Y + DWW+LG L +++ G PPF A++ KL EK++ P + P+ K+LL L Sbjct: 413 KSYGKACDWWSLGALGYDLLTGSPPFKANNHAKLQEKIIKQKLALPYFLGPDAKDLLTRL 472 Query: 253 LQVDPSKRIG-SLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 ++ +P+KR+G + + IK+H +F +DW+A+ +++ P +P+ + P NF Sbjct: 473 MRKEPAKRLGYHMPKDLQTIKNHRFFRKIDWKALERREVAPPILPVVTDPALAENF 528 >UniRef50_UPI00006CD5AE Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 779 Score = 211 bits (515), Expect = 2e-53 Identities = 105/276 (38%), Positives = 168/276 (60%), Gaps = 8/276 (2%) Query: 22 DFDIVKAIGNGAYGEVFLV-RDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 DF + +G G++GEV+LV R+K F AMK+ K VV++N +++ EKK L Sbjct: 453 DFRFISKLGQGSFGEVYLVEREKKLF---AMKIQNKQQVVQKNLQRYVQTEKKALSLFNH 509 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF++ L AF+++ YL+ ++ Y GG+M Y+ K + + Y +Q++LALE LH Sbjct: 510 PFIIKLHYAFQNDWYLFMVMEYAEGGDMGNYLNKRNKLPEDEARIYTAQIVLALEELHKQ 569 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWT--LCGTPEYLAPEVITSKGYSF 197 +++ RD+KP+N+++D G KL DFG K +K+ T+T CG+ YLAPEV+ + +S Sbjct: 570 DIIFRDLKPDNVVLDHLGNAKLTDFGLSKEGIKENTFTKSFCGSVAYLAPEVLAKRPHSR 629 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 +VDW+ LG +E+ G PP++ ++ LY+ + G K P +MS + K+L+K LL +P Sbjct: 630 TVDWYLLGTFLYELLVGIPPYYDNNKEILYDNIRRGPLKIPRSMSADAKDLIKQLLNRNP 689 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 +R+GS K EIK H +F + W I+ K+ AP Sbjct: 690 KERLGS-KRDSEEIKEHQFFKNICWNDIYTGKVKAP 724 >UniRef50_A0CC53 Cluster: Chromosome undetermined scaffold_166, whole genome shotgun sequence; n=7; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_166, whole genome shotgun sequence - Paramecium tetraurelia Length = 736 Score = 211 bits (515), Expect = 2e-53 Identities = 100/283 (35%), Positives = 174/283 (61%), Gaps = 6/283 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++ DF VK IG G + V++V+ K ++AMK+++K +++ + E+ I+ + Sbjct: 253 SLKDFIFVKCIGVGGFSRVYMVKKKSNGRFYAMKLIDKEFILQHKKQGIVQNERDIMTVL 312 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF++ L+ AF+ ++ F+L + +GGE+F +++ ++ +FY +++ LA+ YLH Sbjct: 313 DHPFIIKLEYAFESKNFIIFVLEFCSGGELFWQLRQVKRMTEYQARFYFTEICLAMFYLH 372 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGY 195 +V+RDIKPENILID +G++++ DFG K + ++ CG+PEY+APE++ G+ Sbjct: 373 SLSIVYRDIKPENILIDIDGHIRIADFGLSKPNMTEEDYAYSFCGSPEYMAPEMLLKIGH 432 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPE--NMSPECKNLLKGLL 253 + VD + LG L +E+ G PP+++ D ++YE +L PE N+S E K+LLKGLL Sbjct: 433 NVQVDHYCLGALLYELVTGLPPYYSRDTEEIYESILNEELTFPEKLNLSNEIKDLLKGLL 492 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 PS+R+ + K G+ E+ +H WF D +I +K+ PF P Sbjct: 493 SKQPSERLCANK-GLLELFTHPWFKDCDLVSILLKKVQPPFKP 534 >UniRef50_UPI000069F1C6 Cluster: UPI000069F1C6 related cluster; n=11; Xenopus tropicalis|Rep: UPI000069F1C6 UniRef100 entry - Xenopus tropicalis Length = 348 Score = 210 bits (514), Expect = 3e-53 Identities = 104/312 (33%), Positives = 178/312 (57%), Gaps = 6/312 (1%) Query: 2 LKEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVE 61 +K + +KYS + + DF +K +G G++G+V LV Y A+KV++K + Sbjct: 33 IKPSYAEKYSKKMCF--SARDFRRIKVLGRGSFGKVLLVEYLPANIYCALKVLKKEDINT 90 Query: 62 RNHAKHLILEKKILQCIQFP-FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSD 120 + ++ EK+I + + F+V L F +L+F++ ++AGG + T++ G F Sbjct: 91 LEELQRILAEKEIGKTVNPDNFIVDLYATFSTKFHLFFVMEFVAGGSLRTHLDTCGHFDL 150 Query: 121 SLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWT 177 KFYA+ ++L LE +H +VVHRD+KP N+L+D +GY+K+ DFG K +T T Sbjct: 151 ERAKFYAACILLGLEAVHMKDVVHRDLKPGNLLMDKDGYIKIADFGIGKTGIGYGDRTGT 210 Query: 178 LCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC 237 + G+ Y+APEV+ + Y+ +VDWWALG +++EM G PF D + + + ++ Sbjct: 211 MIGSLAYMAPEVLRKEMYTRAVDWWALGVITYEMLLGKKPFTGYDGDCICDSIVGVEPLF 270 Query: 238 PENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPI 297 PE++ P+ + + LL +P +R+GS +G ++ H +FN + W I +K APF+P Sbjct: 271 PESLDPDAVSFISELLNKNPEERLGSTEGDAADVAEHPFFNNIVWDDILERKATAPFIPS 330 Query: 298 CSSPGDTSNFPE 309 + P D + F E Sbjct: 331 LNGPEDVTYFEE 342 >UniRef50_Q24FD5 Cluster: Protein kinase domain containing protein; n=2; Oligohymenophorea|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 957 Score = 210 bits (514), Expect = 3e-53 Identities = 103/277 (37%), Positives = 171/277 (61%), Gaps = 4/277 (1%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 + F + IG G++GEV+LV K + +AMKV+ KS ++ N ++ + E+ +L + Sbjct: 632 NSFIVHGLIGKGSFGEVYLVEKKDSQQLYAMKVLHKSKIMRHNLTRYALTERNVLSVTKH 691 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF+V L+ AF+ L+ IL Y GG++ ++QK F++ + Y +++ LALE+LH Sbjct: 692 PFIVRLNFAFQTQDKLFLILKYCPGGDLGEHLQKEKRFTEDRVRNYLAEITLALEHLHKK 751 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW--TLCGTPEYLAPEVITSKGYS 196 +V+ RD+KP+NI++D G+ L DFG K VL T + CG+ YLAPE++ G+ Sbjct: 752 DVIFRDLKPDNIVLDHEGHAMLTDFGLSKEGVLDHSTGAKSFCGSVAYLAPEMLKRCGHG 811 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 +VDW+ LG + +E+ G PP++A++ +L+ + G K P +S + ++LLK LLQ + Sbjct: 812 KAVDWYLLGVVMYELLVGIPPYYANNKEELFNNIEKGHLKLPSFLSNDARSLLKALLQRN 871 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 P+KR+GS KG EIK+H +F ++W+ +KL P Sbjct: 872 PAKRLGSGKGDADEIKAHQFFANINWEEAEQRKLNVP 908 >UniRef50_UPI00015A51B8 Cluster: Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).; n=1; Danio rerio|Rep: Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta). - Danio rerio Length = 649 Score = 210 bits (513), Expect = 4e-53 Identities = 106/313 (33%), Positives = 186/313 (59%), Gaps = 12/313 (3%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 +++DF K +G G++G+V L K Y A+K ++K VV+ + + ++EK++L Sbjct: 319 SLNDFVFQKVLGKGSFGKVMLAELKGKGQYFAIKALKKDVVLMDDDVECTMVEKRVLALA 378 Query: 79 -QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 + PF+ L F+ +L+F++ Y+ GG++ +IQ G F FYA+++I L+YL Sbjct: 379 WENPFLTHLYCTFQSKEHLFFVMEYLNGGDLMFHIQDKGRFDLYRATFYAAEIICGLQYL 438 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKG 194 H +V+RD+K +N+++D +G++K+ DFG CK + + + T CGTP+Y+APE++ + Sbjct: 439 HSKGIVYRDLKLDNVMLDKDGHIKIADFGMCKENMIGENRATTFCGTPDYIAPEILLGQK 498 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 YSFSVDWW+ G L +EM G PF D ++L++ + + P ++ E K+LL+ L + Sbjct: 499 YSFSVDWWSFGVLLYEMLIGQSPFQGDDEDELFDSIRMDVPHYPRWITKEAKDLLEKLFE 558 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE---IP 311 DP++R+G + I+ H +F ++W A+ +++ PF P SS D SNF Sbjct: 559 RDPTRRLGV----VGNIRGHAFFKTINWPALEKREVSPPFKPKKSS-SDCSNFDREFLSE 613 Query: 312 QPKLRKVSKYLYE 324 +P+L + K L + Sbjct: 614 KPRLSQSDKNLID 626 >UniRef50_UPI000065FBEC Cluster: Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL).; n=1; Takifugu rubripes|Rep: Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL). - Takifugu rubripes Length = 807 Score = 210 bits (513), Expect = 4e-53 Identities = 111/305 (36%), Positives = 189/305 (61%), Gaps = 16/305 (5%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITF----TYHAMKVVEKSVVVER-NHAKHLILEKKI 74 +++F+++K +G GAYG+VFLVR K++ +AMKV++K+ +V++ A+H E+++ Sbjct: 22 IENFELLKVLGTGAYGKVFLVR-KVSGHDAGKLYAMKVLKKATIVQKAKTAEHTRTERQV 80 Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133 L+ I Q PF+VTL AF+ + L+ IL Y+ GGE+FT++ + F + Y+ +++LA Sbjct: 81 LEHIRQSPFLVTLHYAFQTDTKLHLILDYVNGGELFTHLVQRVRFKEQEVALYSGEIVLA 140 Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK--KKTWTLCGTPEYLAPEVIT 191 LE+LH VV+RD+K ENIL+DS+G++ L DFG K ++ +++CGT EY+APE++ Sbjct: 141 LEHLHKLGVVYRDLKLENILLDSSGHIVLTDFGLSKEFDQVERAFSVCGTIEYMAPEIVE 200 Query: 192 --SKGY-SFSVDWWALGDLSFEMEAGHPPFFASDPNK----LYEKVLVGSYKCPENMSPE 244 G+ +DWW+LG L +E+ G PF N + +++L P+++ P Sbjct: 201 GGESGHDKVILDWWSLGVLMYELLTGGSPFTVDGDNNSHTDIAKRILKKDPPFPKDLGPL 260 Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304 K++++ LL DP KR+GS G +K ++ ++W+ + +K+ APF P+ D Sbjct: 261 AKDIIQRLLVKDPKKRLGSGPNGAENVKKRPFYQKINWEDLAAKKVPAPFKPVIRDELDV 320 Query: 305 SNFPE 309 SNF E Sbjct: 321 SNFAE 325 Score = 104 bits (249), Expect = 4e-21 Identities = 64/202 (31%), Positives = 106/202 (52%), Gaps = 18/202 (8%) Query: 78 IQFPFV-VTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + F F+ V D A L+ Y +L + GGE+ I++ FS++ +++ A+ + Sbjct: 512 LAFSFICVANDAACAAQLHTYLVLELLGGGELLERIRRKQHFSETEASRIMRKLVSAVSH 571 Query: 137 LHYCEVVHRDIKPENILI---DSNGYLKLCDFGFCKVLKKKTWTL---CGTPEYLAPEVI 190 +H VVHRD+KPEN+L N +K+ DFGF ++ L C T +Y APE++ Sbjct: 572 MHDVGVVHRDLKPENLLFTDESENSEIKIIDFGFARLKPPDNQLLKTPCFTLQYAAPEIL 631 Query: 191 TSKGYSFSVDWWALGDLSFEMEAGHPPFFA-------SDPNKLYEKVLVGSY----KCPE 239 GY S D W+LG + + M +G PF + ++ +K+ G + + Sbjct: 632 KYDGYDESCDLWSLGVILYTMLSGQVPFQCQGKSLTHTSAEEIMKKIKQGDFSFEGEAWR 691 Query: 240 NMSPECKNLLKGLLQVDPSKRI 261 N+S + K+L++ LL VDP+KRI Sbjct: 692 NVSQQAKDLIQELLTVDPNKRI 713 >UniRef50_Q4RM42 Cluster: Chromosome 10 SCAF15019, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 10 SCAF15019, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 766 Score = 210 bits (513), Expect = 4e-53 Identities = 110/324 (33%), Positives = 187/324 (57%), Gaps = 13/324 (4%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 + DF ++ +G G++G+V L + A+KV++K ++++ + + + EK++L Q Sbjct: 436 ISDFTFLQVLGKGSFGKVMLAKLNSKDLVFAVKVLKKDIILQDDDVECTMTEKRVLSLAQ 495 Query: 80 -FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 P++ L F+ + L+F++ ++ GG++ +IQK F + +FY +++ AL +LH Sbjct: 496 CHPYLTQLYCCFQTSDRLFFVMEFVNGGDLMFHIQKSRKFEEPRARFYTAEITSALMFLH 555 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLK-KKTWTLCGTPEYLAPEVITSKGY 195 +++RD+K +N+L+D +G+ KL DFG CK + + T T CGTP+Y+APE++ Y Sbjct: 556 SKGILYRDLKLDNVLLDKDGHCKLADFGMCKEGIFEGAATATFCGTPDYIAPEILQEMLY 615 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 SVDWWALG L +EM +GH PF A + + L+E +L +S E N+LK LL Sbjct: 616 GPSVDWWALGVLLYEMLSGHAPFEAENEDDLFESILNEEVLYASWLSTEAVNMLKALLTK 675 Query: 256 DPSKRIGSL--KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312 +P+ R+G + GG I +H +F G+DW+ + ++L PF P + D +NF P+ Q Sbjct: 676 NPAHRLGCVASDGGETAIVNHPFFTGIDWEKLNRRELEPPFKPRIKTAEDVNNFDPDFTQ 735 Query: 313 --PKLRKVSKYLY----EEEFAEF 330 P L + L +EEF F Sbjct: 736 EEPTLTPIDDPLIPSINQEEFLNF 759 >UniRef50_A0BQE1 Cluster: Chromosome undetermined scaffold_120, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_120, whole genome shotgun sequence - Paramecium tetraurelia Length = 678 Score = 210 bits (513), Expect = 4e-53 Identities = 101/275 (36%), Positives = 172/275 (62%), Gaps = 6/275 (2%) Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPF 82 F ++ +G G++G+V+LV+ +AMKV+ KS+++++N ++ I E+ +L PF Sbjct: 367 FKVLGLLGKGSFGQVYLVQKNKKL--YAMKVLLKSMILKQNICRYAITERNVLSVTSHPF 424 Query: 83 VVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEV 142 +V L AF+ L+ IL Y GG++ + K F + L K Y ++ILALE LH ++ Sbjct: 425 IVKLRYAFQTEDKLFMILDYCPGGDLGMLLCKIKRFPEELVKLYTCEIILALEDLHKRDI 484 Query: 143 VHRDIKPENILIDSNGYLKLCDFGFCKV----LKKKTWTLCGTPEYLAPEVITSKGYSFS 198 + RD+KP+NIL+D++G++ L DFG K K + CG+ YLAPE++ +G+ + Sbjct: 485 IFRDLKPDNILLDADGHVLLTDFGLSKEGIPQSSKGAQSFCGSVAYLAPEMLKRQGHGKA 544 Query: 199 VDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPS 258 VDW+ LG + +E+ G PP++ +D + L+ + S K P+++S EC+ LLK LL+ +P+ Sbjct: 545 VDWYLLGVVMYELLVGLPPYYDNDRDTLFYNIENASLKIPQHISIECRTLLKSLLERNPT 604 Query: 259 KRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 KR+GS +G EIK H +F +DW+ + +++L P Sbjct: 605 KRLGSGEGDSLEIKVHPYFADVDWELVLNRELSMP 639 >UniRef50_P43057 Cluster: Protein kinase C-like 1; n=4; Saccharomycetales|Rep: Protein kinase C-like 1 - Candida albicans (Yeast) Length = 1097 Score = 210 bits (513), Expect = 4e-53 Identities = 111/320 (34%), Positives = 179/320 (55%), Gaps = 10/320 (3%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +DDF + +G G +G+V L + T A+KV++K +VE + A+ + EK++ Sbjct: 767 LDDFQFLAVLGKGNFGKVMLAESRHTSKLCAIKVLKKDFIVENDEAESVKSEKRVFLTAN 826 Query: 80 ---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 PF++ L F+ +YF++ YI+GG++ +IQK F+ KFYA +V+L L+Y Sbjct: 827 KEMHPFLLNLHCCFQTENRIYFVMEYISGGDLMWHIQK-NRFTAKRAKFYACEVLLGLKY 885 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193 H +V+RD+K +NIL+ + G++K+ D+G CK K T T CGTPE++APE++ K Sbjct: 886 FHDNGIVYRDLKLDNILLTTKGHIKIGDYGLCKEDMWHKSTTSTFCGTPEFMAPEIVAGK 945 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y SVDWWA G L F+M PF D + ++ + K P N+S + +L+ LL Sbjct: 946 AYDRSVDWWAFGVLLFQMLLCQSPFKGDDEDDIFNAIENDEVKYPINLSRQTVLVLQALL 1005 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE---I 310 DPS+R+GS EI H +F+ +++ + + ++ AP++P S D SNF + Sbjct: 1006 TKDPSQRLGSGPKDAEEIMEHPYFHDVNFDDVLNCRIPAPYIPEVQSEHDYSNFDKEFTS 1065 Query: 311 PQPKLRKVSKYLYEEEFAEF 330 P+L V L E +F Sbjct: 1066 ETPRLTPVETVLTSEMQEQF 1085 >UniRef50_Q91948 Cluster: PKN; n=3; Euteleostomi|Rep: PKN - Xenopus sp. (clawed frog) Length = 901 Score = 210 bits (512), Expect = 5e-53 Identities = 106/326 (32%), Positives = 187/326 (57%), Gaps = 15/326 (4%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++D+F ++ +G G +G+V L K T A+K ++K ++ R+ + L+ EK++ + Sbjct: 570 SLDNFRLLAVLGRGHFGKVLLSEYKETGELFAVKALKKGDIIARDEVESLLCEKRVFVAV 629 Query: 79 Q---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135 PF+++L F+ + F++ Y+AGG+ T+I +FS S FYA+ V+L L+ Sbjct: 630 SDASHPFLLSLLGCFQTADSVCFVMDYMAGGDSMTHIHSE-VFSQSRAMFYAACVLLGLQ 688 Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITS 192 +LH +V+RD+K +N+L+DS GY+KL D+G CK +T T CGTPE+LAPEV+T Sbjct: 689 FLHSRNIVYRDLKLDNLLLDSEGYVKLADYGLCKEGMGPSDRTSTFCGTPEFLAPEVLTD 748 Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252 Y+ +VDWW G L +EM G PF + ++++ ++ + P ++ E +++ L Sbjct: 749 ASYTRAVDWWGFGVLIYEMMVGESPFPGDEEEEVFDSIVNDEVRYPRFLTAEAIAIMRRL 808 Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF----- 307 L+ +P +R+G+ + ++K +F +D++A+ ++L PF P P D SNF Sbjct: 809 LRRNPERRLGAGERDAEDVKKQPFFKDMDFEALLSRRLPPPFTPCVKGPHDISNFDPEFT 868 Query: 308 ---PEIPQPKLRKVSKYLYEEEFAEF 330 PE+ P+ ++ K +E F F Sbjct: 869 CEGPELTPPREPRLLKPEEQESFHGF 894 >UniRef50_A2EX40 Cluster: AGC family protein kinase; n=4; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 431 Score = 210 bits (512), Expect = 5e-53 Identities = 111/296 (37%), Positives = 170/296 (57%), Gaps = 9/296 (3%) Query: 17 DKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ 76 D T+DDF I+ IG G YG+V LVR T +A+K + KS + E + ++ EK I+ Sbjct: 110 DLTMDDFQIISVIGRGYYGKVMLVRRIDTDQLYAIKSIRKSRLAEMDSCS-VLTEKNIMM 168 Query: 77 CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 I PF+V L AF+ + +Y L Y GGE+F Y++ G + Y +++ LAL + Sbjct: 169 KIHHPFIVNLCFAFQTDTKVYLGLEYAPGGELFYYMESNGTIPVDDARLYVAEIGLALAH 228 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKG 194 LH +++RD+KPENIL D++G++KL DFG K L T CGTP+YLAPEVI + Sbjct: 229 LHKYGIIYRDLKPENILFDADGHIKLTDFGLSKELGVDGTAKTFCGTPDYLAPEVIPQEK 288 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 Y+ +D WALG L++EM G PF + N+++++++ PE M P N + LL Sbjct: 289 YTTKIDEWALGVLTYEMILGRTPFCNDNKNEMFQEIVTLDPYFPEGMDPRIINFIMRLLT 348 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309 DP +R ++KS +F G+DW A+++++ ++P T+NF PE Sbjct: 349 KDPKER-----PTFDDVKSDPFFEGVDWDAVYNREHSPSYIPEIKDRMCTNNFDPE 399 >UniRef50_Q02956 Cluster: Protein kinase C zeta type; n=60; Bilateria|Rep: Protein kinase C zeta type - Mus musculus (Mouse) Length = 592 Score = 210 bits (512), Expect = 5e-53 Identities = 106/300 (35%), Positives = 173/300 (57%), Gaps = 12/300 (4%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCI 78 + DFD+++ IG G+Y +V LVR K +AMKVV+K +V + + EK + Q Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L F+ L+ ++ Y+ GG++ ++Q+ + +FYA+++ +AL +LH Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGY 195 +++RD+K +N+L+D++G++KL D+G CK T T CGTP Y+APE++ + Y Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428 Query: 196 SFSVDWWALGDLSFEMEAGHPPF--FASDPNK-----LYEKVLVGSYKCPENMSPECKNL 248 FSVDWWALG L FEM AG PF +P+ L++ +L + P +S + ++ Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488 Query: 249 LKGLLQVDPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 LKG L DP +R+G + G +IKSH +F +DW + ++ + PF P + NF Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQITDDYGLDNF 548 >UniRef50_Q1MX42 Cluster: Protein kinase C, delta V; n=9; Euteleostomi|Rep: Protein kinase C, delta V - Mus musculus (Mouse) Length = 585 Score = 209 bits (511), Expect = 7e-53 Identities = 104/301 (34%), Positives = 179/301 (59%), Gaps = 9/301 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+++F K +G G++G+V L K Y A+K ++K VV+ + + ++EK++L Sbjct: 254 TLENFTFQKVLGKGSFGKVLLAELKGKDKYFAIKCLKKDVVLIDDDVECTMVEKRVLALA 313 Query: 79 -QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 + PF+ L F+ +L+F++ ++ GG++ +IQ G F FYA+++I L++L Sbjct: 314 WESPFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFL 373 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKG 194 H +++RD+K +N+++D +G++K+ DFG CK + + T CGTP+Y+APE++ Sbjct: 374 HSKGIIYRDLKLDNVMLDRDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLK 433 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 YSFSVDWW+ G L +EM G PF D ++L+E + V + P ++ E K++++ L + Sbjct: 434 YSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFE 493 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQP 313 DP KR+G + G I+ H +F ++W + +K+ PF P SP D SNF PE Sbjct: 494 RDPDKRLG-VTG---NIRIHPFFKTINWSLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNE 549 Query: 314 K 314 K Sbjct: 550 K 550 >UniRef50_P90980 Cluster: Protein kinase C-like 2; n=49; Eumetazoa|Rep: Protein kinase C-like 2 - Caenorhabditis elegans Length = 682 Score = 209 bits (511), Expect = 7e-53 Identities = 103/293 (35%), Positives = 173/293 (59%), Gaps = 7/293 (2%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 DF+ + +G G++G+V L K T A+KV++K V+++ + + + EK++L + P Sbjct: 347 DFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALPEKP 406 Query: 82 -FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 F+V L F+ LYF++ ++ GG++ IQ+ G F + + FYA+++ + L +LH Sbjct: 407 SFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSK 466 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYSF 197 +++RD+K +N++++ +G++K+ DFG CK T T CGTP+Y+APE+I + Y Sbjct: 467 GIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQPYGK 526 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 SVDWWA G L FEM AG PPF D ++L+ + + P+++S E +L K LL +P Sbjct: 527 SVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLIKNP 586 Query: 258 SKRIGSL---KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 SKR+G + +IK H +F +DW I +++ PF P + T NF Sbjct: 587 SKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDRSTENF 639 >UniRef50_Q4RZQ9 Cluster: Chromosome 18 SCAF14786, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 18 SCAF14786, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 645 Score = 209 bits (510), Expect = 9e-53 Identities = 106/305 (34%), Positives = 181/305 (59%), Gaps = 10/305 (3%) Query: 36 EVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP-FVVTLDVAFKDNL 94 +V LV K T +A+K+++K VV++ + + ++EK++L P F+ L F+ Sbjct: 328 QVMLVEMKATGELYAVKILKKDVVIQDDDVECTMVEKRVLALQDKPPFLTQLHSCFQTVD 387 Query: 95 YLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILI 154 LYF++ Y+ GG++ +IQ+ G F + FYA+++ + L +LH +++RD+K +N+++ Sbjct: 388 RLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEIAVGLFFLHERGIIYRDLKLDNVML 447 Query: 155 DSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEM 211 DS G++K+ DFG CK V T T CGTP+Y+APE+I + Y SVDWWA G L +EM Sbjct: 448 DSEGHIKIADFGMCKENMVDGVCTRTFCGTPDYIAPEIIAYQPYGLSVDWWAYGVLLYEM 507 Query: 212 EAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEI 271 AG PPF D ++L++ ++ + P+++S E ++ KGL+ PSKR+G + G +I Sbjct: 508 LAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMAKLPSKRLGCGQEGERDI 567 Query: 272 KSHTWFNGLDWQAIFHQKLIAPFVP-ICSSPGDT-SNFPEIPQPKL----RKVSKYLYEE 325 + H +F +DW+ + ++++ PF P +C + F QP+L V + + Sbjct: 568 RDHVFFRRIDWKRLENREIQPPFKPKVCGKAAENFDKFFTRTQPQLTPPDELVIANIDQA 627 Query: 326 EFAEF 330 EFA F Sbjct: 628 EFANF 632 >UniRef50_Q7PRV3 Cluster: ENSANGP00000020017; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000020017 - Anopheles gambiae str. PEST Length = 613 Score = 209 bits (510), Expect = 9e-53 Identities = 104/294 (35%), Positives = 176/294 (59%), Gaps = 6/294 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC-I 78 VDDF + +G G++G+VFL K + Y+A+K ++K VV+E + ++E+K+L Sbjct: 290 VDDFHFLTVLGKGSFGKVFLAELKNSDYYYAIKCLKKDVVLEDDDVDCTLIERKVLALGT 349 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 + PF+ L F+ + +L+F++ Y+ GG++ +IQ+ G F ++ +FYA++++ L++LH Sbjct: 350 KHPFLCHLFCTFQTDSHLFFVMEYLNGGDLMFHIQQSGRFPEARARFYAAEIVSGLKFLH 409 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGY 195 +V+RD+K +N+L+D +G++++ DFG CK+ L K + CGTP+Y+APE+I + Y Sbjct: 410 RKGIVYRDLKLDNVLLDYDGHVRIADFGMCKLEIYLDKLADSFCGTPDYMAPEIIKGQKY 469 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 + +VDWW+ G L +EM G PF D ++L+ + P +S E LL+ LL+ Sbjct: 470 NQAVDWWSFGVLVYEMLVGQSPFSGCDEDELFWSICNEIPWFPHYLSKEALRLLQSLLEK 529 Query: 256 DPSKRIGSLKGGIYE--IKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 D S R+G L E IK H +FN + W + + + PF P P DT F Sbjct: 530 DASIRLGVLNTMDEESDIKYHPFFNSIIWDKLERRAVEPPFKPQVRHPLDTQYF 583 >UniRef50_Q6CBU3 Cluster: Yarrowia lipolytica chromosome C of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome C of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 478 Score = 209 bits (510), Expect = 9e-53 Identities = 109/294 (37%), Positives = 172/294 (58%), Gaps = 7/294 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T DF+ +K +G GA+G+V LVR+K T +A K ++K+ ++ A E+ IL+ + Sbjct: 134 TTSDFEPIKVLGCGAFGKVLLVREKSTGHLYAQKQLKKASMIVEKKALQTKTERAILESV 193 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 + P++V L A +D LY IL Y GGE+F ++ + + FY +++ILAL +LH Sbjct: 194 RHPYIVKLFYALQDQEKLYLILEYAQGGELFHHLATEHMLPEQTASFYVAEMILALSHLH 253 Query: 139 Y-CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKT-WTLCGTPEYLAPEVITSKGYS 196 VV+RD+KPEN ++D +G+L L DFG KV T T GTPEY+APEV+ K Y Sbjct: 254 LNVGVVYRDLKPENCMLDQDGHLVLTDFGLSKVATNDTCTTFSGTPEYMAPEVLQGKEYD 313 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKV-LVGSYKCPENMSPECKNLLKGLLQV 255 +SVDWW+LG ++F++ G+PPF +D K+ K+ + + P +S + K+ L G L+ Sbjct: 314 YSVDWWSLGAVTFDLLTGNPPFTGNDYQKILAKIDKCKAMRYPFYLSQDAKDFLNGCLKK 373 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQ--KLIAPFVPICSSPGDTSNF 307 P++R+GS + ++K +F LDW + + L P P+ + P NF Sbjct: 374 CPNRRLGS--RDLEKVKKMRFFRKLDWDLLEARDPSLEPPIKPLITDPILAENF 425 >UniRef50_A5DM82 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 1047 Score = 209 bits (510), Expect = 9e-53 Identities = 113/320 (35%), Positives = 180/320 (56%), Gaps = 10/320 (3%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +DDF + +G G +G+V L + T T A+KV++K +VE + A+ + EK++ Sbjct: 717 LDDFQFLAVLGKGNFGKVMLAESRQTQTLCAIKVLKKDFIVENDEAESVKSEKRVFLTAN 776 Query: 80 ---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 PF++ L F+ +YF++ YI+GG++ +IQK FS KFYA +V+LAL+Y Sbjct: 777 KAMHPFLLNLHCCFQTENRIYFVMEYISGGDLMWHIQK-SRFSAKRAKFYACEVLLALKY 835 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK---KKTWTLCGTPEYLAPEVITSK 193 H +V+RDIK +NIL+ + G++K+ D+G CK T T CGTPE++APE+I+ K Sbjct: 836 FHENGIVYRDIKLDNILLTTKGHIKIGDYGLCKENMWQGNTTATFCGTPEFMAPEIISGK 895 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y +VDWWALG L F+M PF D ++++ + + P NM + +L+ LL Sbjct: 896 QYDRAVDWWALGVLLFQMLLCQSPFKGDDEDEIFNAIEHDDVRYPINMPRQTVLVLQALL 955 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE---I 310 DP R+GS EI H +F+ +++ I + ++ P++P +S D SNF + Sbjct: 956 TKDPLSRLGSGPRDAEEIMDHPYFSDVNFDDILNLRVQPPYIPEITSEHDYSNFDKEFTS 1015 Query: 311 PQPKLRKVSKYLYEEEFAEF 330 P+L V L E +F Sbjct: 1016 ETPRLTPVDTVLTSEMQEQF 1035 >UniRef50_UPI00006CFE83 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 890 Score = 208 bits (509), Expect = 1e-52 Identities = 104/275 (37%), Positives = 166/275 (60%), Gaps = 5/275 (1%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 DF I+ A+G G++G VFLV+ T AMK+++K ++ + K+ + E IL+ + P Sbjct: 572 DFTILGALGKGSFGRVFLVQQNSTEELFAMKMLKKVSLIMKRQLKYAVTECNILKRCKNP 631 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 FVV L AF+ +LY +L Y GG + +IQ+ FS+ +F+ ++ILA+EYLH Sbjct: 632 FVVGLHYAFQTPNHLYMVLDYCNGGVLLQHIQRESRFSELTARFFVCEIILAIEYLHSQN 691 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGYSFS 198 +++RD+KPENILI S+G++KL DFG K T + CG+P YL+PE++ KG+S + Sbjct: 692 ILYRDLKPENILISSDGHIKLTDFGLSKEHVADFDVTKSFCGSPAYLSPEMLLGKGFSKA 751 Query: 199 VDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPS 258 D + +G + +EM G PPFF D +LY + + P+ +S K L+ LL+ +P Sbjct: 752 SDIYGIGCVLYEMLTGQPPFFHEDIKQLYSGIKSEDPQLPKYLSNSAKTLIIQLLKKNPK 811 Query: 259 KRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 +R+G I +IKSH +F G+DW ++ ++ P Sbjct: 812 ERLG--YNSIQQIKSHEFFEGIDWHRVYEKQYQPP 844 >UniRef50_A0BNJ0 Cluster: Chromosome undetermined scaffold_118, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_118, whole genome shotgun sequence - Paramecium tetraurelia Length = 662 Score = 208 bits (509), Expect = 1e-52 Identities = 97/280 (34%), Positives = 178/280 (63%), Gaps = 6/280 (2%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81 DF +K IG G + V+LVR K T ++A+K+++K ++ + + ++ E+ I+ + P Sbjct: 254 DFIFLKNIGVGGFSLVYLVRKKDTGKFYALKLIDKEFIIAKKKQQIVLNERNIMTLLNSP 313 Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141 F++ L AF+ ++ F+L + GGE+F +++ S+ FY S++ L L+ +H Sbjct: 314 FLLHLSYAFESRQFVVFVLEFCQGGELFFQLKQIKRMSEEQACFYISEICLGLQEIHSLN 373 Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGYSFS 198 +++RDIKPENIL+D G++++ DFG K ++K ++ CG+PEY+APE++ G+S + Sbjct: 374 ILYRDIKPENILMDIEGHVRIADFGLSKPEIGREEKAYSFCGSPEYMAPEMLLKLGHSQT 433 Query: 199 VDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--MSPECKNLLKGLLQVD 256 VD++ LG L +E+ G PP+++++ N++Y+ +L P + +S E K+LL LL+ D Sbjct: 434 VDFYCLGALLYELLTGLPPYYSTNTNQIYQDILYSKLSFPNDLTLSREVKSLLIALLEKD 493 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 P +R+G+ KGG+ EI H +F+ +D++ + +K+ PF P Sbjct: 494 PIQRLGA-KGGVQEILKHPFFSQIDFKQLALKKVKPPFKP 532 >UniRef50_Q24GE7 Cluster: Protein kinase domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 671 Score = 208 bits (508), Expect = 2e-52 Identities = 105/290 (36%), Positives = 167/290 (57%), Gaps = 5/290 (1%) Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77 KTV D++ + +G+GA+G+V LV+DK Y+AMK++ K + N K+ + EK + Sbjct: 359 KTVQDYEYYRILGSGAFGKVILVKDKKNQKYYAMKIISKEKFQQLNLMKYALSEKNAMSK 418 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 +Q PF+V L AF+ L+ I Y GG + ++ F + K Y Q+ILA+E L Sbjct: 419 MQHPFIVKLHYAFQTKRKLFLIQQYCGGGSLGRMLKIKQRFDEQTAKKYMCQIILAIEAL 478 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTWTLCGTPEYLAPEVITSKGY 195 H ++ RD+KP+NI++D G L DFG K V + + GTP YL PE+I G+ Sbjct: 479 HDNLIIFRDLKPDNIVLDEEGNAYLVDFGLAKLGVYDEINKSFLGTPAYLPPEIIVKDGH 538 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNK--LYEKVLVGSYKCPENMSPECKNLLKGLL 253 + DW+A+G + +E+ G PF + ++ LYE++ S K P N+S EC+++++ LL Sbjct: 539 NRMADWYAVGIVLYELLMGCTPFNQGNVSREVLYERIKQNSIKIPSNISSECQDIIQKLL 598 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303 +P KR+G G EI+SH WF G+DW+ + +K+ P I + P + Sbjct: 599 CKNPKKRLGYKNDG-KEIRSHPWFEGIDWEKVIQKKIPMPKPVIRTIPNE 647 >UniRef50_A0E0G1 Cluster: Chromosome undetermined scaffold_71, whole genome shotgun sequence; n=5; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_71, whole genome shotgun sequence - Paramecium tetraurelia Length = 779 Score = 208 bits (508), Expect = 2e-52 Identities = 106/285 (37%), Positives = 162/285 (56%), Gaps = 10/285 (3%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T++DF +K +G G +G +LV+D H MK V K V+ N +H+ EK++L+ + Sbjct: 462 TLEDFIGLKLLGEGTFGNAYLVKDIPQQNMHVMKCVPKVNVIANNTERHIKNEKQVLELL 521 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 P +V +FKD Y+Y + Y+ G E+F I++ G+ + T+FY +Q+I LE LH Sbjct: 522 NHPNLVCFRRSFKDQNYIYLLTEYVKGKELFHVIREIGLLNSYETQFYIAQMINILEKLH 581 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK---KKTWTLCGTPEYLAPEVITSKGY 195 +++RD+KPEN ++ NGY+KL D G KVLK KT+TL GTP Y+APE++ KGY Sbjct: 582 SQHIIYRDVKPENFIVMENGYIKLIDMGTAKVLKSRASKTYTLVGTPHYMAPEILKGKGY 641 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFA---SDPNKLYEKVLVGSYKCPENMSP-ECKNLLKG 251 SFS D W+LG +E+ G PF DP + E +L G + P+ + + L+ Sbjct: 642 SFSTDLWSLGICFYELMCGEVPFAGDEEDDPFIIEEAILNGKLEYPQILKDFKAIKLMDQ 701 Query: 252 LLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 L+ P R+G G +K H WF+G W+ + +L P+ P Sbjct: 702 LMNRTPELRLG---GSFEALKVHPWFDGFQWEELEAFQLKPPYYP 743 >UniRef50_Q6BHW6 Cluster: Debaryomyces hansenii chromosome G of strain CBS767 of Debaryomyces hansenii; n=3; Saccharomycetaceae|Rep: Debaryomyces hansenii chromosome G of strain CBS767 of Debaryomyces hansenii - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 449 Score = 208 bits (508), Expect = 2e-52 Identities = 114/310 (36%), Positives = 184/310 (59%), Gaps = 17/310 (5%) Query: 16 YDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEK-SVVVERNHAKH------L 68 Y + DF+ +K +G GAYG+V LVR+ T A K ++K S+V+ + H Sbjct: 93 YKPKLSDFEPIKVLGRGAYGKVILVREISTNRLFAQKQLKKASLVINETNEIHQINYSRT 152 Query: 69 ILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYAS 128 I EK IL+ + P +V+L AF+DN +Y IL Y++GGE+F ++ + S+ +Y + Sbjct: 153 INEKSILEIVNHPNIVSLYYAFQDNDKVYLILEYLSGGELFHHLAQEKFMSEKNASYYIA 212 Query: 129 QVILALEYLH-YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV--LKKKTWTLCGTPEYL 185 Q+ILAL YLH V++RD+KPEN +++S G L L DFG KV +K ++ GT +Y+ Sbjct: 213 QIILALRYLHNKLGVIYRDLKPENCMLNSYGNLVLTDFGLSKVSTTDEKKHSMTGTVQYM 272 Query: 186 APEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSP 243 APE++ S+ Y++SVDWW+LG +++++ G PPF ++ K+ EKV+ + K P +S Sbjct: 273 APEILKSEPYTYSVDWWSLGCVAYDLLTGSPPFNGNNNKKIIEKVISSKKTLKFPFYLSL 332 Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAI----FHQKLIAPFVPICS 299 + K+LL+ LLQ +P KR ++ +K H +F +DW + + + + P +PI + Sbjct: 333 DAKDLLRKLLQPNPYKRF-NIDNDFDLLKKHRFFRHIDWSQLESPDYQLETLPPILPIIT 391 Query: 300 SPGDTSNFPE 309 P NF E Sbjct: 392 DPILAENFDE 401 >UniRef50_P36583 Cluster: Protein kinase C-like 2; n=1; Schizosaccharomyces pombe|Rep: Protein kinase C-like 2 - Schizosaccharomyces pombe (Fission yeast) Length = 1016 Score = 208 bits (508), Expect = 2e-52 Identities = 98/296 (33%), Positives = 174/296 (58%), Gaps = 7/296 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78 ++DF + +G G +G+V L K +A+KV++K ++E + + EK++ Sbjct: 680 LEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVAN 739 Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + PF+V L F+ +YF++ +++GG++ +IQ+ FS +FYA++V LAL+Y Sbjct: 740 RERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQEQ-FSRRRAQFYAAEVCLALKY 798 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193 H +++RD+K +NIL+ +G++K+ D+G CK T T CGTPE++APE++ + Sbjct: 799 FHDNGIIYRDLKLDNILLSPDGHVKVADYGLCKEDMWHDNTTATFCGTPEFMAPEILLEQ 858 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y+ SVDWWA G L ++M G PF D ++++ +L P +M + ++L+ LL Sbjct: 859 QYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYPIHMPRDSVSILQQLL 918 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 DP KR+GS ++ +H +F+ ++W I+H++ P++P +SP DT F E Sbjct: 919 TRDPKKRLGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPYIPSLNSPTDTKYFDE 974 >UniRef50_UPI00015B57A5 Cluster: PREDICTED: similar to CG10261-PE; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CG10261-PE - Nasonia vitripennis Length = 716 Score = 208 bits (507), Expect = 2e-52 Identities = 101/305 (33%), Positives = 182/305 (59%), Gaps = 15/305 (4%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++ DF++++ IG G+Y +V +V K T +AMKV++K++V + + EK + + Sbjct: 199 SLSDFELIRVIGRGSYAKVLMVELKQTKRIYAMKVIKKALVTDDEDIDWVQTEKHVFETA 258 Query: 79 Q-FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 PF+V L F+ L+F++ ++ GG++ ++Q+ + +FYA+++ LAL +L Sbjct: 259 SNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMFHMQRQRRLPEEHARFYAAEISLALNFL 318 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKG 194 H +++RD+K +N+L+D G++KL D+G CK ++ T T CGTP Y+APE++ + Sbjct: 319 HTKGIIYRDLKLDNVLLDHEGHVKLTDYGMCKEGVREGDTTATFCGTPNYIAPEILRGED 378 Query: 195 YSFSVDWWALGDLSFEMEAGHPPF----FASDPNK-----LYEKVLVGSYKCPENMSPEC 245 Y FSVDWWALG L +EM AG PF + +P++ L++ +L + + P ++S + Sbjct: 379 YGFSVDWWALGVLVYEMLAGRSPFDIAGASENPDQNTEDYLFQVILQKTIRIPRSLSVKA 438 Query: 246 KNLLKGLLQVDPSKRIGSLK--GGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303 ++LKG L DP++R+G + +I +H +F +DW + +++ P+ P S D Sbjct: 439 TSVLKGFLCKDPAERLGCGRSPNAFLDIMTHPFFKAIDWDMLEQKQVTPPYKPQLDSDRD 498 Query: 304 TSNFP 308 +NFP Sbjct: 499 LANFP 503 >UniRef50_UPI0000499007 Cluster: hypothetical protein 139.t00021; n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical protein 139.t00021 - Entamoeba histolytica HM-1:IMSS Length = 982 Score = 208 bits (507), Expect = 2e-52 Identities = 108/299 (36%), Positives = 174/299 (58%), Gaps = 14/299 (4%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 +V DFDI+K GAY ++LV+ K T +AMKV++K ++ +N +++EK L Sbjct: 610 SVTDFDIIKKFSAGAYSRIYLVKKKSTGDVYAMKVMKKDDMIRKNVVDSVLVEKNFLSKA 669 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 VV L AF+D++ LY ++ Y GG++ T ++ G F++ + Y+++++L+L Y+H Sbjct: 670 HNISVVKLYYAFQDDINLYLVMEYCPGGDLATLLEHIGSFNEYVAHVYSAEILLSLHYIH 729 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGF------CKVLKKKTWTLCGTPEYLAPEVITS 192 VH+DIKP+NILI+ NG+L L DFG + KT C TP+Y APE++ S Sbjct: 730 ALGCVHKDIKPDNILINRNGHLVLTDFGLSSYGLVSQETAGKTGIFC-TPDYAAPEILIS 788 Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPE--NMSPECKNLLK 250 YSF+ D++ALG + +E G+PPF AS P ++ K+ G Y+ PE ++S +CK+L+ Sbjct: 789 NSYSFASDYFALGCMLYEFVVGYPPFNASTPEAIFMKIQQGVYEWPEDVDVSDDCKDLVS 848 Query: 251 GLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 LL +P KR +I++H +F+ + W +F + FVP DT F + Sbjct: 849 KLLCPEPEKR-----PVFKQIENHPFFSDIHWDTLFDESREDIFVPQLDGDNDTGYFED 902 >UniRef50_A2DA20 Cluster: AGC family protein kinase; n=2; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 442 Score = 208 bits (507), Expect = 2e-52 Identities = 100/291 (34%), Positives = 162/291 (55%), Gaps = 7/291 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+DDF+I+ +G G YG+V LV+ K T +A+K + K+ +++ + E+ IL + Sbjct: 106 TMDDFNIISVLGRGYYGKVMLVQKKGTKNLYAIKSIHKARLIQTRKVHTVFSERNILMKV 165 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 + PF+V+L AF+ Y + YI GGE+F Y+ K G S +FYA+++ LAL +LH Sbjct: 166 KHPFIVSLSFAFQSMSKFYLGMQYIPGGELFRYLSKVGKLQMSEVRFYAAEIGLALSHLH 225 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK--KKTWTLCGTPEYLAPEVITSKGYS 196 +++RD+KPENIL+D G++KL DFG K + T T CGT EYLAPE++ + Y Sbjct: 226 SNGIIYRDLKPENILLDEEGHIKLTDFGLAKDMSFDSATSTFCGTVEYLAPEIVRREPYG 285 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 ++DWW+ G L +E GH PF+ + K++ ++ P + P + + LL D Sbjct: 286 MAIDWWSYGCLVYEFIFGHTPFYDENRAKIFMRIPADQPYYPSDFDPNVSDFINQLLSKD 345 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 P R +K H ++ G+D+ + +K+ +VP + NF Sbjct: 346 PETR-----ATFDTLKDHPFWEGMDFDEVLERKVEPLYVPPIDDKFNPENF 391 >UniRef50_UPI00015B53AD Cluster: PREDICTED: similar to RHO kinase, putative; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to RHO kinase, putative - Nasonia vitripennis Length = 1419 Score = 207 bits (506), Expect = 3e-52 Identities = 112/302 (37%), Positives = 176/302 (58%), Gaps = 16/302 (5%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 DDF ++K IG GA+GEV LVR K T +AMK++ K +++R+ + E+ I+ Sbjct: 110 DDFTLIKVIGRGAFGEVQLVRHKSTQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAHANS 169 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 ++V L AF+D YLY ++ Y+ GG++ + +Y + + KFY ++V+LAL+ +H Sbjct: 170 EWIVQLHFAFQDQKYLYMVMDYMPGGDLVNLMSQYDV-PEKWAKFYCAEVVLALDAIHNM 228 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLK----KKTWTLCGTPEYLAPEVITSKG-- 194 VHRD+KP+N+L+D +G+LKL DFG C + ++ T GTP+Y++PEV+ S+G Sbjct: 229 GFVHRDVKPDNMLLDKHGHLKLADFGTCMRMDVDGLVRSDTAVGTPDYISPEVLQSQGGE 288 Query: 195 --YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPE--NMSPECKNL 248 Y DWW++G +EM G PF+A Y K++ S P+ ++S K+L Sbjct: 289 GVYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHRNSLHFPQELDISHSAKSL 348 Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFP 308 + G L D SKR+G + G+ EIKSH +F W ++ + P VP S DTSNF Sbjct: 349 ICGFL-TDRSKRLG--RNGVDEIKSHAFFKNDQWTFENLRECVPPVVPELSGDDDTSNFD 405 Query: 309 EI 310 ++ Sbjct: 406 DV 407 >UniRef50_O62569 Cluster: Serine/Threonine protein kinase; n=1; Suberites domuncula|Rep: Serine/Threonine protein kinase - Suberites domuncula (Sponge) Length = 763 Score = 207 bits (506), Expect = 3e-52 Identities = 98/294 (33%), Positives = 177/294 (60%), Gaps = 5/294 (1%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC-I 78 +++F +K +G G++G+V L + + Y+A+K ++K VV+E + + ++EK+IL Sbjct: 433 LEEFQFLKLLGKGSFGKVLLAQQIGSNKYYAIKALKKDVVLEDDDVEATMVEKRILALGS 492 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 + PFV L F+ + +L+F++ Y+ GG++ +IQ + F +FYA++++ L++LH Sbjct: 493 ECPFVTHLHSTFQSSSHLFFVMEYLNGGDLMFHIQLHHKFKLPRARFYAAEILAGLQFLH 552 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKT-WTLCGTPEYLAPEVITSKGY 195 +++RD+K +NIL+DS G+ K+ DFG C+ + T T CGTP+Y++PE+I K Y Sbjct: 553 SKGIIYRDLKLDNILLDSEGHCKIADFGMCRENIFGSSTAGTFCGTPDYISPEIIKGKRY 612 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 +FSVD+W+ G L +EM G PPF D ++L++ + + + L LLQ Sbjct: 613 TFSVDFWSYGVLCYEMITGQPPFGGEDEDELFDSICNSQIPFSRYLDAYTIDFLDKLLQR 672 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 +P +R+G + G I+ H +F +D+ + +++ AP+ P+ S D SNF + Sbjct: 673 EPIQRLGYM-GDRQPIRKHPFFRSIDFARLEKREIAAPYKPVVKSAQDASNFDD 725 >UniRef50_UPI0000499488 Cluster: hypothetical protein 137.t00011; n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical protein 137.t00011 - Entamoeba histolytica HM-1:IMSS Length = 974 Score = 207 bits (505), Expect = 4e-52 Identities = 110/297 (37%), Positives = 174/297 (58%), Gaps = 12/297 (4%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +DDF+++K GAY +++LV+ K T +AMKV +KS + +N ++ EKKILQ Sbjct: 597 LDDFEVIKKFSEGAYSKLYLVKKKTTGDVYAMKVSKKSDMKRKNVIDGVLAEKKILQLSN 656 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 VV L AF+D+ L+ ++ Y GG++ ++ +S+ + Y +++ILALEY+H Sbjct: 657 TRSVVKLYYAFQDSSNLFLVMEYCPGGDLRCILRNLNYLEESVVRIYTAEIILALEYIHS 716 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK-------KKTWTLCGTPEYLAPEVITS 192 +HRD+KP+N+LID NG+L L DFG V K++ LC TP+Y+APE + Sbjct: 717 LGCIHRDLKPDNVLIDKNGHLLLTDFGLSVVGLCNEQHGIKESRLLC-TPDYVAPESLRD 775 Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPE--NMSPECKNLLK 250 Y + D+++LG + +EM G PPF PN+++E + G Y PE N+S ECK+ + Sbjct: 776 YYYCQASDYFSLGCMVYEMLLGIPPFHCDSPNQIFELIKEGIYDWPEDVNISEECKDFVN 835 Query: 251 GLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 GLL VD ++R+G+ I EIK+H W + + ++ + FVP + DT F Sbjct: 836 GLLTVDYNQRLGA--KSIDEIKNHKWMKPISFDSLLSESREDIFVPELENELDTGYF 890 >UniRef50_Q69G16 Cluster: Protein kinase C type beta; n=2; Bilateria|Rep: Protein kinase C type beta - Schistosoma mansoni (Blood fluke) Length = 618 Score = 207 bits (505), Expect = 4e-52 Identities = 104/276 (37%), Positives = 162/276 (58%), Gaps = 4/276 (1%) Query: 36 EVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP-FVVTLDVAFKDNL 94 EV L K T +A+K+++K VV++ + ++E+++L + P F+V L F+ Sbjct: 302 EVMLAERKDTDELYAVKILKKDVVLQDDDVDCAMIERRVLALQRKPPFLVQLHSTFQTMD 361 Query: 95 YLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILI 154 LYF++ ++ GG++ IQK G F + + FYA++V + L +LH D+K +N+L+ Sbjct: 362 RLYFVMEFVNGGDLMFRIQKEGKFKEPIAVFYAAEVAVGLFFLHDSRNYLSDLKLDNLLL 421 Query: 155 DSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEM 211 D++G++K+ DFG CK T T CGTP+Y+APE++ K Y SVDWW+ G L +EM Sbjct: 422 DADGHIKIADFGMCKDGITGDVTTHTFCGTPDYIAPEILLYKPYGKSVDWWSYGVLLYEM 481 Query: 212 EAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEI 271 AG PPF D L+ +L + P+++S E ++ K LL DP KR+G G EI Sbjct: 482 LAGQPPFEGEDEEDLFANILQHTISYPKSLSKESVSICKALLTRDPMKRLGCGSDGEKEI 541 Query: 272 KSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 K H +F +DW I + + P+ P+ SP DTSNF Sbjct: 542 KEHLFFRRIDWDKIALRLVQPPYKPVTLSPRDTSNF 577 >UniRef50_O75116 Cluster: Rho-associated protein kinase 2; n=115; Eumetazoa|Rep: Rho-associated protein kinase 2 - Homo sapiens (Human) Length = 1388 Score = 206 bits (504), Expect = 5e-52 Identities = 112/306 (36%), Positives = 176/306 (57%), Gaps = 16/306 (5%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 +D+D+VK IG GA+GEV LVR K + +AMK++ K +++R+ + E+ I+ Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 149 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 P+VV L AF+D+ YLY ++ Y+ GG++ + Y + + KFY ++V+LAL+ +H Sbjct: 150 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSM 208 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLC----GTPEYLAPEVITSKG-- 194 ++HRD+KP+N+L+D +G+LKL DFG C + + C GTP+Y++PEV+ S+G Sbjct: 209 GLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGD 268 Query: 195 --YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPEN--MSPECKNL 248 Y DWW++G +EM G PF+A Y K++ S PE+ +S KNL Sbjct: 269 GFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNL 328 Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFP 308 + L D R+G + G+ EI+ H +F W ++ AP VP SS D+SNF Sbjct: 329 ICAFL-TDREVRLG--RNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFD 385 Query: 309 EIPQPK 314 +I K Sbjct: 386 DIEDDK 391 >UniRef50_UPI0000D562F1 Cluster: PREDICTED: similar to CG3324-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG3324-PA - Tribolium castaneum Length = 636 Score = 206 bits (503), Expect = 6e-52 Identities = 111/294 (37%), Positives = 170/294 (57%), Gaps = 15/294 (5%) Query: 17 DKTVDDFDIVKAIGNGAYGEVFLVRD--KITFTYHAMKVVEKSVVVERNHAKHLILEKKI 74 D + DF ++ +G G +G V LV+ K + A+K ++K V+ + H + + EK I Sbjct: 312 DLNLSDFHVISTLGIGGFGRVELVQHSGKKELVF-ALKCMKKYVIAAQKHQELVFNEKNI 370 Query: 75 LQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYI--QKYGIFSDSLTKFYASQVIL 132 + F+V L ++D +LYF+L GG+++T++ QK ++ KFY + V+ Sbjct: 371 QIVCKNNFIVRLYRTYRDKKFLYFLLEPCLGGDLWTHLYKQKPRFLDENHAKFYTACVVE 430 Query: 133 ALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK------KKTWTLCGTPEYLA 186 A YLH +++RD+KPEN+LID+ GY+KL DFGF K LK KKT+T GTPEY+ Sbjct: 431 AFNYLHERLIIYRDLKPENLLIDAKGYVKLTDFGFAKKLKMIKKCVKKTYTFAGTPEYVP 490 Query: 187 PEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPN--KLYEKVLVG--SYKCPENMS 242 PE++ ++G+ +VD+WALG FE+ G PF D K Y+ +L G + P+++S Sbjct: 491 PEIMLNQGHDKAVDYWALGVFVFELLTGKTPFRTDDVTYMKTYKLILKGIDDVEFPKHVS 550 Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 E L+K L + P +R+G GGI ++K H WF G DW K+ APF P Sbjct: 551 VEAVKLVKELCKSTPPQRLGCGSGGILDVKGHEWFGGFDWGRFEGGKMPAPFRP 604 >UniRef50_UPI00006CBA83 Cluster: Protein kinase domain containing protein; n=2; Tetrahymena thermophila SB210|Rep: Protein kinase domain containing protein - Tetrahymena thermophila SB210 Length = 414 Score = 206 bits (503), Expect = 6e-52 Identities = 116/319 (36%), Positives = 184/319 (57%), Gaps = 17/319 (5%) Query: 17 DKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ 76 D T DFD ++ +G+GAYG+V LV+ K AMK+++KS +V RN +I+EK +L Sbjct: 85 DLTYKDFDRLQNLGSGAYGDVILVKKKTNNKQFAMKIIKKSKIVSRNLNPQMIIEKNVLL 144 Query: 77 CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 + PF+V L +F+ LY ++ Y GGE++TY+ FS +++F A++V+L LEY Sbjct: 145 ENKHPFLVRLKYSFQTEKKLYLVMEYCPGGELYTYLVNNKKFSIEVSRFIAAEVLLGLEY 204 Query: 137 LH-YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVI-- 190 LH ++++RD+KPENILI +G+LK+ DFG K K++ T TL GTPEY+APEVI Sbjct: 205 LHKSMKIIYRDLKPENILISEDGHLKIADFGLAKQFKREDELTTTLRGTPEYIAPEVILA 264 Query: 191 --TSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPN--KLYEKVLVGSYKCPENMSPECK 246 T KGY D WA G FE+ +G+PPF + N + +K+L + + + E + Sbjct: 265 EQTGKGYGLQCDIWAFGIFLFEIISGNPPFTDKNRNWAGIKQKILQNKPQFTADFTEESQ 324 Query: 247 NLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSN 306 +L+ L+ +P +R EIK H +F+ +DW+ + + + +P + P N Sbjct: 325 DLICKCLKDNPLER-----PNWDEIKVHPFFSKIDWEVLLSKGIESPLKKLI--PKRQGN 377 Query: 307 FPEIPQPKLRKVSKYLYEE 325 + P+P + YE+ Sbjct: 378 LIQRPRPIFETQTNDKYEQ 396 >UniRef50_Q4SK04 Cluster: Chromosome 10 SCAF14571, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 10 SCAF14571, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1382 Score = 205 bits (501), Expect = 1e-51 Identities = 113/306 (36%), Positives = 171/306 (55%), Gaps = 16/306 (5%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80 +DF+ VK IG GA+GEV LVR K + +AMK++ K +++R+ + E+ I+ Sbjct: 43 EDFEKVKIIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 102 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 P+VV L AF+D YLY ++ Y+ GG++ Y + + KFY ++V++AL+ +H Sbjct: 103 PWVVQLCCAFQDEHYLYMVMEYMPGGDLVNLTSTYDV-PEKWAKFYTAEVVMALDAIHSM 161 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLC----GTPEYLAPEVITSKG-- 194 +HRD+KP+N+L+D NG+LKL DFG C + C GTP+Y++PEV+ S+G Sbjct: 162 GFIHRDVKPDNMLLDRNGHLKLADFGTCMKMDSTGMVHCDTAVGTPDYISPEVLKSQGGD 221 Query: 195 --YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPE--NMSPECKNL 248 Y DWW++G FEM G PF+A Y K++ S P+ ++S +N+ Sbjct: 222 GYYGRECDWWSVGVFIFEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPDDVDISKNARNI 281 Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFP 308 + L D R+G + G+ EIK H +F W + +AP VP SS DTSNF Sbjct: 282 ICAFL-TDREVRLG--RNGVEEIKQHPFFKNDQWTFDTIRDTVAPVVPELSSDIDTSNFD 338 Query: 309 EIPQPK 314 EI K Sbjct: 339 EIEDDK 344 >UniRef50_A0D8K8 Cluster: Chromosome undetermined scaffold_41, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_41, whole genome shotgun sequence - Paramecium tetraurelia Length = 698 Score = 204 bits (498), Expect = 2e-51 Identities = 105/311 (33%), Positives = 175/311 (56%), Gaps = 8/311 (2%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77 + F + +G G +G+V+LV +KI Y+AMK+++K + N K +EK +L+ Sbjct: 389 ESFQFYQKLGEGGFGQVYLV-EKIGQEPKKYYAMKILQKEDIDTSNIIKSAQIEKDVLKI 447 Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 + PF+V L+ AF+ +LY ++ GG++ T+++ F + + K YA+++ LALE L Sbjct: 448 MNHPFIVKLNYAFQTLDHLYLVMDLCPGGDLATHLELVNQFPEHIVKIYAAEITLALEAL 507 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKG 194 H ++ RD+KPEN+++D +G+ +L DFG K + + CGT YLAPE++ KG Sbjct: 508 HQQGIIFRDLKPENVVLDKDGHAQLTDFGLSKQGIDEEMLNQSFCGTLAYLAPEMLMKKG 567 Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254 + VDW+ LG +E+ G PP++ ++ L E + K P ++S E K+++ LL Sbjct: 568 HGRQVDWYMLGIFIYELLVGAPPYYDAEKEILKENIKRAPLKIPRHLSQEAKDIIIQLLI 627 Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPK 314 DP +R+G K EIKSH WFN ++WQ +++KL P IC P K Sbjct: 628 RDPKRRLG-CKEDAKEIKSHPWFNDINWQDCYNKKLQPPKPLICHEPKAARKVTFSKDSK 686 Query: 315 LRKVSKYLYEE 325 K++ + + E Sbjct: 687 RNKLNDWTFFE 697 >UniRef50_Q05655 Cluster: Protein kinase C delta type; n=61; Eumetazoa|Rep: Protein kinase C delta type - Homo sapiens (Human) Length = 676 Score = 204 bits (498), Expect = 2e-51 Identities = 100/294 (34%), Positives = 177/294 (60%), Gaps = 8/294 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ-CI 78 +++F K +G G++G+V L K Y A+K ++K VV+ + + ++EK++L Sbjct: 346 INNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTMVEKRVLTLAA 405 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 + PF+ L F+ +L+F++ ++ GG++ +IQ G F FYA++++ L++LH Sbjct: 406 ENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLH 465 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195 +++RD+K +N+L+D +G++K+ DFG CK + + T CGTP+Y+APE++ Y Sbjct: 466 SKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKY 525 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 +FSVDWW+ G L +EM G PF D ++L+E + V + P ++ E K++L+ L + Sbjct: 526 TFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFER 585 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 +P+KR+G + G IK H +F ++W + ++L PF P SP D SNF + Sbjct: 586 EPTKRLG-MTG---NIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQ 635 >UniRef50_UPI00015B4E6B Cluster: PREDICTED: hypothetical protein; n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical protein - Nasonia vitripennis Length = 972 Score = 204 bits (497), Expect = 3e-51 Identities = 111/309 (35%), Positives = 183/309 (59%), Gaps = 22/309 (7%) Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTY---HAMKVVEKSVVVERNH-AKHLILEKKILQCI 78 FD++K +G GAYG+VFLVR +I +AMKV++K+ +V++ +H E+++L+ + Sbjct: 121 FDLLKVLGTGAYGKVFLVRKRIGVDVGQLYAMKVLKKATIVQKKKMTEHTKTERQVLEAV 180 Query: 79 Q-FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137 + PF+VTL AF+ + L+ IL Y++GGE+FT++ + F++ + Y ++ILALE L Sbjct: 181 RDSPFLVTLHYAFQTDAKLHLILDYVSGGELFTHLYQRDKFTEDEVRIYVGEIILALEQL 240 Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-------KKKTWTLCGTPEYLAPEVI 190 H +++RDIK ENIL+D G++ L DFG K +T++ CGT EY+APEV+ Sbjct: 241 HKLGIIYRDIKLENILLDREGHIILTDFGLSKEFLPHERDSNPRTYSFCGTIEYMAPEVV 300 Query: 191 T--SKGYSFSVDWWALGDLSFEMEAGHPPFFA----SDPNKLYEKVLVGSYKCPENMSPE 244 S G++ +VDWW++G L++E+ G PF + +++ ++L P +SP Sbjct: 301 RGGSAGHNVAVDWWSVGVLTYELLTGSSPFTVEGEKNTQSEISRRILKMDPPMPTFLSPT 360 Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFN----GLDWQAIFHQKLIAPFVPICSS 300 ++ + LL DP R+G E+K H +F +W A+ +++ PFVP + Sbjct: 361 VRDFIARLLTKDPRVRLGGGPRDAKELKEHDFFRIAPPPFNWSALERREVPPPFVPRITH 420 Query: 301 PGDTSNFPE 309 DTSNF E Sbjct: 421 ELDTSNFSE 429 Score = 98.7 bits (235), Expect = 2e-19 Identities = 76/266 (28%), Positives = 128/266 (48%), Gaps = 20/266 (7%) Query: 6 FNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHA 65 F ++ D+ + + D + +G+G++ R + T A+K++ + V + H Sbjct: 488 FATRFEDSTFFQQYELDIH-EEPLGDGSFSVCRRCRHRQTGQEFAVKILSRRV--DCGHE 544 Query: 66 KHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKF 125 L+ C P +V L +D + Y ++ ++GGE+ T + FS+ Sbjct: 545 ASLLRS-----CQGHPNIVKLIEVHQDRAHNYIVMELLSGGELLTR-SRTAPFSEQQASA 598 Query: 126 YASQVILALEYLHYCEVVHRDIKPENILIDSNGY---LKLCDFGFCKVLK--KKTWTLCG 180 Q+ AL ++H V+HRDIKPEN++ +G +KL DFGF + + + T C Sbjct: 599 IMRQLGSALRFMHSRGVLHRDIKPENLVFAHSGPDAPIKLVDFGFACMKRSCEPLHTPCF 658 Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG-----SY 235 T Y APEV+ + Y S D W+LG + + M + PPF P+ L ++ G S Sbjct: 659 TLPYAAPEVLANLDYDESCDIWSLGAVLYSMLSDRPPFRTGSPD-LASRISSGEVDFDSE 717 Query: 236 KCPENMSPECKNLLKGLLQVDPSKRI 261 +S + LLKGLL +PS+R+ Sbjct: 718 DMRTKISSLGRQLLKGLLAPEPSQRL 743 >UniRef50_UPI000069DCCB Cluster: UPI000069DCCB related cluster; n=10; Xenopus tropicalis|Rep: UPI000069DCCB UniRef100 entry - Xenopus tropicalis Length = 338 Score = 204 bits (497), Expect = 3e-51 Identities = 102/288 (35%), Positives = 170/288 (59%), Gaps = 10/288 (3%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++++F++ K +G G +G+VFL K T A+K ++K ++ +N K + EK+ILQ + Sbjct: 5 SLENFNLGKVLGEGTFGKVFLAEYKDTKQLCAIKTLKKERIIAKNDIKSVFKEKRILQKV 64 Query: 79 ---QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135 + PF+V+L F+ +L+F++ Y+ GG++ ++ G F +S FY + ++L LE Sbjct: 65 TSAEHPFLVSLYATFQSENHLFFVMEYLPGGDLCHLLEHQGAFEESKAMFYTACIVLGLE 124 Query: 136 YLHYCEVVHR--DIKPENILIDSNGYLKLCDFGFCKV-----LKKKTWTLCGTPEYLAPE 188 LH +VHR D+K EN+++D +GYLK+ DFG K ++ TLCGT Y+APE Sbjct: 125 ELHRNNIVHRFRDLKLENLMVDVHGYLKIVDFGLSKDGNGFRYGDRSKTLCGTNCYMAPE 184 Query: 189 VITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNL 248 +I YS +VDWWALG + + M PF A D +L+E + E +S E + L Sbjct: 185 IIDEMAYSRAVDWWALGVVLYVMIMFQFPFDAEDDMELFESIRNDKPALTEELSEEAQCL 244 Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 + LL+ +P +R+G + G E+K+H +F +DW+ ++L+ PF P Sbjct: 245 ILRLLEKNPCRRLGYSEAGAEEVKAHEFFEDIDWEEFLERELMPPFKP 292 >UniRef50_A2E224 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 451 Score = 204 bits (497), Expect = 3e-51 Identities = 104/301 (34%), Positives = 167/301 (55%), Gaps = 13/301 (4%) Query: 4 EDFNKKYSDAPIYDKT--VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVE 61 +++ KK+ + ++ K+ + DF I++ +G+G YG+V L K + +A+K + KS +V Sbjct: 86 QNWIKKFKELTLHQKSLSISDFRIIRTLGSGFYGKVLLAEHKQSKKIYAIKSIHKSRLVN 145 Query: 62 RNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDS 121 + + E+ IL Q PF+V + +F+++ Y L Y++GGE+F I+ Sbjct: 146 DDKINTIFSERNILLLSQHPFIVGIKFSFQNDKKFYLGLEYVSGGELFKLIETGHCVPFQ 205 Query: 122 LTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL------KKKT 175 +FY +V LAL+YLH V++RD+K EN+L+ +G++KL DFG K++ T Sbjct: 206 QVRFYVMEVALALDYLHSIGVIYRDLKLENVLMTKSGHIKLTDFGLSKIVADGKADNSTT 265 Query: 176 WTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSY 235 T CGTPEYLAPE+I SK Y +DWWALG ++E PF K Y+ +L Sbjct: 266 STFCGTPEYLAPEMILSKDYGIEIDWWALGVFTYEFSYTITPFVGKTNKKTYDNILHEEP 325 Query: 236 KCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFV 295 K P N P + + L+ DP+KR + K +IK H +F G+ W + ++K+ P Sbjct: 326 KFPPNADPNLVSFIMMCLRKDPTKR-ATFK----DIKKHPFFEGISWDDVLNKKITPPRK 380 Query: 296 P 296 P Sbjct: 381 P 381 >UniRef50_A2DL59 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 436 Score = 204 bits (497), Expect = 3e-51 Identities = 100/292 (34%), Positives = 171/292 (58%), Gaps = 8/292 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++ FDI+ +G GA+G+V LVR + + +A+K ++K +++ + +I E+ IL Sbjct: 115 SMSSFDILHVLGRGAFGKVMLVRHRSSMKLYAIKSIQKRKLLDAMKSHTVIAERNILMKA 174 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L AF++ Y L Y+ GGE+F ++ K G F + + Y++++ LAL YLH Sbjct: 175 HHPFIVQLFFAFQNPSKFYLGLEYVPGGELFYHLTKRGTFPINEVRLYSAEIALALSYLH 234 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGY 195 +++RD+KPEN+++DS G++KL DFG L++ + CGT YL+PE+I Y Sbjct: 235 SIGIIYRDLKPENVMLDSTGHIKLTDFGLSTEVFELEECGDSFCGTSRYLSPEMIYKIKY 294 Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255 + +DWW+LG L +EM GHPPF + + ++LY + P + + K+L+ LL Sbjct: 295 THKIDWWSLGILMYEMIVGHPPFDSQNRSQLYNDITHSDPVFPSSFPVDAKDLVCKLLTK 354 Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 +P++R G IK H +F G+DW +++++ F+P ++P S F Sbjct: 355 NPNQR-PDFSG----IKDHVFFKGIDWDKVYNREYQPNFIPKQTTPNCDSVF 401 >UniRef50_A0E888 Cluster: Chromosome undetermined scaffold_82, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_82, whole genome shotgun sequence - Paramecium tetraurelia Length = 664 Score = 204 bits (497), Expect = 3e-51 Identities = 100/277 (36%), Positives = 168/277 (60%), Gaps = 4/277 (1%) Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPF 82 F + IG G++GEV+LV T AMKV+ KS + ++N ++ + E+ +L + PF Sbjct: 351 FKVHALIGKGSFGEVYLVEKLDTNQLLAMKVLHKSKIQKQNLTRYALTERNVLSLTKHPF 410 Query: 83 VVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEV 142 +V L AF+ L I+ Y GG++ +++++ F + K Y +Q+ILALE LH ++ Sbjct: 411 IVRLRYAFQTADKLCLIMDYCPGGDLSSHLRREQRFPEERVKLYLTQMILALEDLHKRDI 470 Query: 143 VHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWT----LCGTPEYLAPEVITSKGYSFS 198 + RD+KP+NI++D++GY L DFG K ++ +T CG+ YLAPE++ G+ + Sbjct: 471 IFRDLKPDNIVLDADGYAMLTDFGLSKEGVQEHYTGARSFCGSVAYLAPEMLKRCGHGKA 530 Query: 199 VDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPS 258 VDW+ LG + +E+ G PP++A+D +L+ + K P +S + NLLK LLQ +P+ Sbjct: 531 VDWYLLGVVMYELLVGQPPYYANDREELFNNIQKADLKLPTYISHDGINLLKALLQRNPA 590 Query: 259 KRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFV 295 KR+GS KG EIK+H +F ++W + +++ P + Sbjct: 591 KRLGSGKGDAEEIKAHPYFKDIEWGKVKDKEIKMPIL 627 >UniRef50_A0BQV0 Cluster: Chromosome undetermined scaffold_121, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_121, whole genome shotgun sequence - Paramecium tetraurelia Length = 554 Score = 204 bits (497), Expect = 3e-51 Identities = 100/286 (34%), Positives = 163/286 (56%), Gaps = 2/286 (0%) Query: 9 KYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHL 68 K S I DF ++ +G G++G+V+LV+ K Y+AMK++ K + +++ Sbjct: 235 KVSRVEIQQVGPQDFSVLSQLGKGSFGQVYLVQRKGNTNYYAMKILFKKKIQAAGIVRYI 294 Query: 69 ILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYAS 128 E+KIL + PF+V L AF+ LY IL Y GG++ + + G + K YA Sbjct: 295 QTERKILTYVTSPFIVKLHHAFQTENKLYMILDYCPGGDLEQLMNERGKLPEKAAKAYAC 354 Query: 129 QVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK-KKTWTLCGTPEYLAP 187 +++LALE LH +V+RD+KP N++ID +G+ L DFG K L ++ + CG+ YLAP Sbjct: 355 EILLALETLHQNCIVYRDLKPSNVVIDKDGHALLTDFGLSKELNAQRATSFCGSYAYLAP 414 Query: 188 EVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKN 247 E++ G+ + +DW+ G +E+ G PPF+ D N +Y+ + P+N+S + + Sbjct: 415 EMLDKSGHGYPLDWYLFGVFIYELVHGKPPFYERDRNTMYKNIKNTDPPRPQNISDDLWD 474 Query: 248 LLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 LL LL+ + SKR+GS K E+K+H WF ++WQ + +K P Sbjct: 475 LLMRLLEKNQSKRLGS-KEDAEELKNHPWFKNVNWQQVIQRKQPVP 519 >UniRef50_P13677 Cluster: Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC) (dPKC53E(EY)); n=5; Eumetazoa|Rep: Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC) (dPKC53E(EY)) - Drosophila melanogaster (Fruit fly) Length = 700 Score = 204 bits (497), Expect = 3e-51 Identities = 100/292 (34%), Positives = 168/292 (57%), Gaps = 4/292 (1%) Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI-QF 80 DF+ VK IG G++G+V L + T +A+KV+ K V+++ + + + EKKIL + Sbjct: 370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRP 429 Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140 PF+V++ F+ L+F++ Y GG++ ++Q+YG F +S+ FYA +V +AL +LH Sbjct: 430 PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHER 489 Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197 ++++RD+K +NIL+D G++KL DFG K ++ T T CGTP Y+APE+++ YS Sbjct: 490 DIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSI 549 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 + DWW+ G L FE AG PF D ++ + P++ S E +++ L P Sbjct: 550 AADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKP 609 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 + R+G+ + EI +H +F +DW ++ P P+ D SNF + Sbjct: 610 NNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDD 661 >UniRef50_Q4RRU3 Cluster: Chromosome 7 SCAF15001, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 7 SCAF15001, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 798 Score = 203 bits (496), Expect = 4e-51 Identities = 111/272 (40%), Positives = 167/272 (61%), Gaps = 14/272 (5%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY---HAMKVVEKSVVVER-NHAKHLILEKKIL 75 +++F+++K +G GAYG+VFLVR +AMKV++K+ +V++ +H E+++L Sbjct: 21 MENFELLKVLGTGAYGKVFLVRKNSGHDVGQLYAMKVLKKAAIVQKAKTTEHTRTERQVL 80 Query: 76 QCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILAL 134 + I Q PF+VTL AF+ L+ IL Y++GGEMFT++ + FS+ + Y ++ILAL Sbjct: 81 EHIRQSPFLVTLHYAFQTQSKLHLILDYVSGGEMFTHLYQRDHFSEEAVRIYIGEIILAL 140 Query: 135 EYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEVI 190 E+LH +V+RDIK ENIL+DS G++ L DFG K K++T++ CGT EY+APE+I Sbjct: 141 EHLHKLGIVYRDIKLENILLDSEGHIVLTDFGLSKEFLEEEKERTYSFCGTIEYMAPEII 200 Query: 191 TSK-GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC----PENMSPEC 245 K G+ SVDWW+LG L FE+ G PF +V +C P + Sbjct: 201 RGKAGHGKSVDWWSLGILMFELLTGASPFTLEGERNSQSEVSKRILRCDPPFPSMIGHTA 260 Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWF 277 ++LLK LL DP KR+GS +IK+H +F Sbjct: 261 QDLLKKLLVKDPHKRLGSGPRAAEDIKAHPFF 292 Score = 117 bits (281), Expect = 5e-25 Identities = 77/268 (28%), Positives = 128/268 (47%), Gaps = 27/268 (10%) Query: 29 IGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLDV 88 +G G++ R K + +A+K+V + + E N + + + C P +V L Sbjct: 436 LGEGSFSVCRKCRHKQSGRDYAVKIVSRRM--EANTQREIAA---LRHCESHPNIVKLHE 490 Query: 89 AFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIK 148 F D + Y ++ + GGE+ I+K +F ++ ++ A+ ++H VVHRD+K Sbjct: 491 VFTDQYHTYLVMELLRGGELLERIKKKKLFGEAEASQLLQSLVSAVSFMHEAGVVHRDLK 550 Query: 149 PENILIDSNG---YLKLCDFGF---CKVLKKKTWTLCGTPEYLAPEVITSKGYSFSVDWW 202 PEN+L G LK+ DFGF C T C T +Y APE+ S GY + D W Sbjct: 551 PENVLFADEGEDSTLKVIDFGFARLCPAGSAPLQTPCFTLQYAAPELFESAGYDKACDLW 610 Query: 203 ALGDLSFEMEAGHPPF-------FASDPNKLYEKVLVGSYKCP----ENMSPECKNLLKG 251 +LG + + M +G PF +S + K+ G + + +S + K L+KG Sbjct: 611 SLGVILYTMLSGQVPFQSEQRGMTSSHAADIMHKIKEGDFSLDGESWKGVSDDAKELVKG 670 Query: 252 LLQVDPSKRIGSLKGGIYEIKSHTWFNG 279 LL VDP R+ + ++K ++W G Sbjct: 671 LLTVDPESRL-----KLSDLKENSWLQG 693 >UniRef50_A2E474 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 434 Score = 203 bits (496), Expect = 4e-51 Identities = 102/280 (36%), Positives = 160/280 (57%), Gaps = 7/280 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 +++DF+I+ IG G YG+V LV+ K + +A+K ++K ++E + A +I E+ L Sbjct: 105 SMNDFNIISVIGKGFYGKVMLVQHKTSGELYALKTIQKRRLIETHKAHTVIAERNSLMKA 164 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L AF+ Y L Y +GGE+F ++ K G S + ++++ LAL YLH Sbjct: 165 SHPFIVRLCFAFQTPQKFYLGLEYASGGELFYHLDKAGALPPSEVRLISAEIALALSYLH 224 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTWTLCGTPEYLAPEVITSKGYS 196 +V+RD+KPEN++ DS G++KL DFG K V T TLCGT EYL+PEV+ Y Sbjct: 225 SLGIVYRDLKPENVMFDSEGHVKLTDFGLSKDIVETNSTNTLCGTTEYLSPEVVLHNQYD 284 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 + VDWWALG L +EM PF + +K+ + ++ + PE + P+ +L LL D Sbjct: 285 YGVDWWALGCLMYEMLTERTPFENPNRSKMLQDIVHAQPEFPEFLPPDVIEVLSALLSKD 344 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 P R GI ++K +F LD+ +F ++ ++P Sbjct: 345 PKNR-----PGIDQLKEFAYFKCLDFNKVFRREYTPEYIP 379 >UniRef50_A0DCJ0 Cluster: Chromosome undetermined scaffold_45, whole genome shotgun sequence; n=7; Oligohymenophorea|Rep: Chromosome undetermined scaffold_45, whole genome shotgun sequence - Paramecium tetraurelia Length = 775 Score = 203 bits (496), Expect = 4e-51 Identities = 105/308 (34%), Positives = 170/308 (55%), Gaps = 16/308 (5%) Query: 26 VKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVT 85 +K I G +G V+LV+ K + +K K+ + E+ K ++ +L+ + FPF+++ Sbjct: 452 IKTIAYGQFGPVYLVKAKYNQQLYVLKAFNKNQINEQTLEKQYLMLFLLLEIVNFPFIIS 511 Query: 86 LDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHR 145 FKD L +YF+L Y+ G E+F I+ G+ S ++FY + +IL EYLH+ +++R Sbjct: 512 FMKTFKDTLDVYFLLEYVRGMELFDVIRDIGLLSTYDSQFYVASMILITEYLHHQNIIYR 571 Query: 146 DIKPENILIDSNGYLKLCDFGFCKVLKKK-----TWTLCGTPEYLAPEVITSKGYSFSVD 200 DIKPEN ++D G+LKL D G K++K K T+T+ GTP Y+APE+I KGY+ VD Sbjct: 572 DIKPENFMVDDKGFLKLIDLGTAKIVKGKQGIIRTYTIIGTPHYMAPEIICGKGYNCLVD 631 Query: 201 WWALGDLSFEMEAGHPPF--FASDPNKLYEKVLVGSYKCPENM-SPECKNLLKGLLQVDP 257 W++G +E G PF A DP ++YE+++ P + + K L+ LL P Sbjct: 632 LWSIGICLYEFMCGMVPFGEEAEDPYEIYEEIIKKDITYPNYLKDKKAKKLMDQLLSRVP 691 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPKLRK 317 R+G G +K + WF DW+ + +++ P++P P D PE+ L + Sbjct: 692 EVRLG---GSYASLKGNPWFENFDWEKLLEKEIKTPYLP----PAD-KLLPELEIKSLEQ 743 Query: 318 VSKYLYEE 325 K + EE Sbjct: 744 NGKMIEEE 751 >UniRef50_A0CUG4 Cluster: Chromosome undetermined scaffold_28, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_28, whole genome shotgun sequence - Paramecium tetraurelia Length = 532 Score = 203 bits (496), Expect = 4e-51 Identities = 96/286 (33%), Positives = 173/286 (60%), Gaps = 6/286 (2%) Query: 7 NKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAK 66 N+K YD + + ++K + G G+V LV+ T Y+ K+++K V+ +H Sbjct: 197 NQKQPIRKSYDYS-QQYRLLKYLYQGMLGQVILVQSIKTDKYYVFKLMQKQDVITTDHLN 255 Query: 67 HLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFY 126 H ++E+K+L+ PF++ L AF+ + L ++LP+ GG+++T+++K + KF Sbjct: 256 HALIERKLLEIFDHPFIIKLVQAFETDDQLIYVLPFYQGGDLYTHLKKETRLKEERVKFL 315 Query: 127 ASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEY 184 +Q+I+AL Y+H + V+RD+KPENIL+DS+GY+ L D G CK L + +++ G+ EY Sbjct: 316 VAQLIMALGYMHDKDYVYRDLKPENILMDSSGYIALTDLGLCKQLPNNQLSYSFTGSVEY 375 Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--MS 242 +APE+IT+ GY+ +DWW LG L++E+ G PF+ + ++++E + + N +S Sbjct: 376 IAPEMITAVGYNRMIDWWMLGILAYELIFGITPFYCDNQSQVFESIQEREVRFSTNIAIS 435 Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQ 288 ECK+ + LL+ DP +R+G K +++ H WF +++ I + Sbjct: 436 LECKDFITNLLRKDPKERLG-FKRDFIDLQLHQWFKDINFGEIIRK 480 >UniRef50_Q6P5Z2 Cluster: Serine/threonine-protein kinase N3; n=20; Mammalia|Rep: Serine/threonine-protein kinase N3 - Homo sapiens (Human) Length = 889 Score = 203 bits (496), Expect = 4e-51 Identities = 101/294 (34%), Positives = 171/294 (58%), Gaps = 7/294 (2%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ--- 76 + DF + +G G +G+V LV+ K T Y+A+K ++K V+ R+ + L EK+IL+ Sbjct: 556 LQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVG 615 Query: 77 CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 C PF+++L F+ + + F+ ++ GG++ I + +F + +FY + V+L L++ Sbjct: 616 CTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHE-DVFPEPQARFYVACVVLGLQF 674 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193 LH ++++RD+K +N+L+D+ G+LK+ DFG CK +T T CGTPE+LAPEV+T + Sbjct: 675 LHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQE 734 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y+ +VDWW LG L +EM G PF ++++ ++ P +S + ++ LL Sbjct: 735 AYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLL 794 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 Q P KR+G+ + EIK +F +WQA+ + + PFVP P D F Sbjct: 795 QKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYF 848 >UniRef50_A2E8U1 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 417 Score = 203 bits (495), Expect = 6e-51 Identities = 97/284 (34%), Positives = 161/284 (56%), Gaps = 7/284 (2%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 ++DDF I+ IGNG YG+V L + K T +A+K + K +VE ++ E+ IL Sbjct: 99 SIDDFTILDEIGNGQYGKVKLAKKKDTGDLYAIKTLHKQKLVEMQKIHTIMCERNILSKA 158 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+V L AF+ + Y + Y+ GG +F +++ G K Y +++ +AL +LH Sbjct: 159 SCPFIVQLHYAFQSDTKFYLCMEYVPGGTLFDHMRLSGTIPPDALKLYTAELAIALHHLH 218 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK--TWTLCGTPEYLAPEVITSKGYS 196 +V+RD+KPEN+L+D +G++KL DFG K + + + CGTP+Y+APE++ K Y+ Sbjct: 219 VNHIVYRDLKPENVLLDEDGHIKLTDFGSSKQIDESGTLHSFCGTPDYIAPEIVEGKPYT 278 Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256 VDWW+LG L +EM PPF++ +P + Y+K++ G+ P + +L++GLL D Sbjct: 279 SKVDWWSLGILIYEMVFKAPPFYSVNPKRTYDKIVNGNIIFPGVVDENLVSLIRGLLNKD 338 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300 P +R G E+ H +G + + + F+P +S Sbjct: 339 PMRRF-----GYNEVMYHPLLSGFEINGLLKRAYTPNFLPSSAS 377 >UniRef50_A0CP93 Cluster: Chromosome undetermined scaffold_23, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_23, whole genome shotgun sequence - Paramecium tetraurelia Length = 618 Score = 203 bits (495), Expect = 6e-51 Identities = 104/295 (35%), Positives = 174/295 (58%), Gaps = 8/295 (2%) Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITF-TYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 D F K +G GA+G V+LV+ K + +AMKV+ K + ++ ++ EK IL I Sbjct: 308 DSFTYHKELGKGAFGIVYLVKKKDEQNSLYAMKVLRKEKISQKL-LPYIQTEKSILSVID 366 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 PF+V L AF+ L+ ++ + GG++ + S+ + K Y +++ILA+E LH Sbjct: 367 HPFIVKLHYAFQTQHKLFLVMDFCPGGDLTKLLDLKSRLSEQVAKMYTAEIILAIEALHQ 426 Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTWTLCGTPEYLAPEVITSKGYSF 197 ++++RD+KP+NI+ID+ G+ L DFG K + + T + CGTP Y+APEV+ K Y+ Sbjct: 427 NKIMYRDLKPQNIIIDNKGHCMLTDFGLAKTDIENENTKSFCGTPAYMAPEVVNRKFYNR 486 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPE-NMSPECKNLLKGLLQVD 256 SVDW+ LG ++ EM G PP+++ + +L+E + K P+ N+S E + ++ LL+ + Sbjct: 487 SVDWYQLGTITHEMLFGMPPYYSHNREELFENIKNKQLKFPQNNLSKEALSFIQQLLERN 546 Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT--SNFPE 309 P+KR+G+ K E+K+H WF+ ++W ++KL P I + T NF E Sbjct: 547 PTKRLGAKKDS-EEVKAHPWFSDINWDLAINKKLPVPMPSIMNQANQTLQVNFDE 600 >UniRef50_Q4SLK1 Cluster: Chromosome 15 SCAF14556, whole genome shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 15 SCAF14556, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 395 Score = 202 bits (494), Expect = 8e-51 Identities = 94/193 (48%), Positives = 131/193 (67%), Gaps = 4/193 (2%) Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSF 197 H C + R + ++ + +G+ ++ DFGF K +K +TWTLCGTPEYLAPE+I SKGY+ Sbjct: 207 HACGRLLRPVPVAHVWL--SGF-QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNK 263 Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257 +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S + K+LL+ LLQVD Sbjct: 264 AVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDL 323 Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPKLRK 317 +KR G+LK G+ +IK H WF DW AI+ +K PF+P C PGDTSNF + + ++R Sbjct: 324 TKRYGNLKNGVNDIKGHKWFATTDWIAIYERK-ATPFIPKCRGPGDTSNFDDYEEEEIRV 382 Query: 318 VSKYLYEEEFAEF 330 +EFAEF Sbjct: 383 SLTEKCAKEFAEF 395 Score = 161 bits (391), Expect = 2e-38 Identities = 67/143 (46%), Positives = 106/143 (74%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +DDFD +K +G G++G V LV+ K T Y AMK+++K VV+ +H + EK+ILQ + Sbjct: 59 LDDFDRLKTLGTGSFGRVMLVKHKGTEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVS 118 Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139 FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+ +FYA+Q++L EYLH Sbjct: 119 FPFLVKLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 178 Query: 140 CEVVHRDIKPENILIDSNGYLKL 162 ++++RD+KPEN+LID +GY+++ Sbjct: 179 LDLIYRDLKPENLLIDHHGYIQV 201 >UniRef50_A2FIJ5 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 461 Score = 202 bits (494), Expect = 8e-51 Identities = 95/299 (31%), Positives = 173/299 (57%), Gaps = 5/299 (1%) Query: 11 SDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLIL 70 ++ P ++D F++ K IG GA G+V+L K T A+K + K + ++ + Sbjct: 101 TEPPSEKVSIDSFNLKKVIGRGASGKVYLAEKKSTGERFAIKAIRKDSLPQKKRVSRVRA 160 Query: 71 EKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQV 130 E+ L + F+ L AF+ LYF++ Y AGG++ ++ + FS + Y +++ Sbjct: 161 ERNALMRAKHQFITRLFYAFQSPTKLYFVMEYEAGGDLRHHMDQNTSFSLPQIRIYLAEL 220 Query: 131 ILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKT--WTLCGTPEYLAPE 188 LAL+ LH +V+RD+KPENIL+D+ G++KL DFG K + ++ ++CGT EY+APE Sbjct: 221 ALALKTLHGLGIVYRDLKPENILLDAEGHIKLADFGLAKEINSESDATSICGTCEYIAPE 280 Query: 189 VITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNL 248 ++ S+ +F+VDWW+ G ++F++ PF +++P +L++ ++ + P N+ ++ Sbjct: 281 MLRSQPQTFAVDWWSFGVIAFQLLCNRLPFASANPQRLFQLIMNNQPRIPNNLDSSAQSF 340 Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307 L+ LL +P+KR+GS+ +I H +F +DW + +++ FVP +P NF Sbjct: 341 LQQLLNKEPAKRLGSVG---TDITHHPFFEDIDWDMVANKEYKLDFVPSLETPDSVENF 396 >UniRef50_A0DYT2 Cluster: Chromosome undetermined scaffold_7, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_7, whole genome shotgun sequence - Paramecium tetraurelia Length = 854 Score = 202 bits (494), Expect = 8e-51 Identities = 102/290 (35%), Positives = 168/290 (57%), Gaps = 8/290 (2%) Query: 8 KKYSDAPIYDK-TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAK 66 +K + I DK + F +V+ IG G++G V+ + K A+K EK ++ + K Sbjct: 514 EKSNSYSIQDKINLSSFQVVEMIGKGSFGNVY--KAKYKHINCAIKQQEKDKLIRNGYLK 571 Query: 67 HLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFY 126 ++I E +IL+ I+ PF+V L ++F+ YLY + G++ Y+ + I ++ KF Sbjct: 572 YIISELQILRTIRHPFIVKLYLSFQTQFYLYIVTELCPAGDLSKYMTRGQILNEYTAKFI 631 Query: 127 ASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWT---LCGTPE 183 +Q+ILA+EYLH ++++RD+KPENILID GY+KL DFG CK +T CG+P Sbjct: 632 IAQIILAIEYLHSQQIIYRDLKPENILIDQEGYIKLTDFGLCKQFDGNDFTASSFCGSPA 691 Query: 184 YLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSP 243 YL PE++T + D + +G + +EM G+PPF+ D L EK+ S P+N+S Sbjct: 692 YLPPELVTGGVSLKATDIYQIGTILYEMLTGYPPFYTQDLKSLMEKIKYDSLFIPKNISL 751 Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 E ++LLK +L+ DP +R+G + +K H +F +DW ++ ++ P Sbjct: 752 EAQDLLKRMLKKDPEERLG--YNDVSVLKKHMFFAEIDWDRLYTKQYKPP 799 >UniRef50_A5DZ73 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 1157 Score = 202 bits (494), Expect = 8e-51 Identities = 107/320 (33%), Positives = 175/320 (54%), Gaps = 10/320 (3%) Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79 +DDF + +G G +G+V L + T A+KV++K +VE + A+ + EK++ Sbjct: 827 LDDFQFLAVLGKGNFGKVMLAESRHTQKLCAIKVLKKDFIVENDEAESVKSEKRVFLTAN 886 Query: 80 ---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136 PF++ L F+ +YF++ YI+GG++ +IQ F+ K+YA +V+L L+Y Sbjct: 887 KEMHPFLLNLHCCFQTENRIYFVMEYISGGDLMWHIQN-NRFTARRAKYYACEVLLGLKY 945 Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK---KKTWTLCGTPEYLAPEVITSK 193 H +V+RD+K +NIL+ + G++K+ D+G CK T T CGTPE++APE++T K Sbjct: 946 FHDSGIVYRDLKLDNILLTTKGHIKIADYGLCKENMWHGNTTSTFCGTPEFMAPEIVTGK 1005 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y SVDWWA G L F+M PF D + ++ + K P ++S +L+ LL Sbjct: 1006 KYDRSVDWWAFGVLLFQMLLCQSPFKGDDEDDIFNAIEHDEVKFPVSLSGPTVLVLQALL 1065 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE---I 310 DP +R+GS + EI H +F +++ + + ++ PF+P S D SNF + Sbjct: 1066 TKDPQQRLGSSERDAEEIMEHPYFQDVNFDDVLNCRVPPPFIPELKSEHDYSNFDKEFTS 1125 Query: 311 PQPKLRKVSKYLYEEEFAEF 330 P+L V L E +F Sbjct: 1126 ETPRLTPVETVLTSEMQEQF 1145 >UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|Rep: CG4839-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 1003 Score = 202 bits (493), Expect = 1e-50 Identities = 103/294 (35%), Positives = 177/294 (60%), Gaps = 12/294 (4%) Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64 +F+ +YS I + + +G GA+G V LV A+K+++K VV+++ Sbjct: 681 EFDNEYSQVAI-----SELKKIATLGCGAFGRVDLVAYNQQAL--ALKIIKKIEVVKQDQ 733 Query: 65 AKHLILEKKIL-QCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLT 123 +H+ EK ++ +C Q PF+V L ++++ Y+YF++ GG+++T + K F + Sbjct: 734 IEHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTA 793 Query: 124 KFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLK--KKTWTLCGT 181 KF A V+ A +YLH ++RD+KPEN+++ ++GY KL DFGF K ++ +KT T GT Sbjct: 794 KFIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQNEKTNTFAGT 853 Query: 182 PEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPE 239 PEY+APE+I +G+ +VD+WALG L +E+ G PF + K+Y+++L G P Sbjct: 854 PEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPS 913 Query: 240 NMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293 + ++L++ L + P++R+G + GI +IK H+WF LDWQ + ++L +P Sbjct: 914 RIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSP 967 >UniRef50_Q23DN8 Cluster: Cyclic nucleotide-binding domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic nucleotide-binding domain containing protein - Tetrahymena thermophila SB210 Length = 808 Score = 202 bits (493), Expect = 1e-50 Identities = 100/274 (36%), Positives = 159/274 (58%), Gaps = 12/274 (4%) Query: 32 GAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLDVAFK 91 G +G V+LV+ +A+K K + E++ K++ EK +L+ + FPF++ +FK Sbjct: 490 GQFGPVYLVKANYDKNLYALKSFNKVQISEQSLEKYICQEKVVLEIVNFPFIIQYARSFK 549 Query: 92 DNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPEN 151 D+ +YF++ Y+ G E+F I+ G+ + ++FY + +IL LEYLH+ V++RD+KPEN Sbjct: 550 DSFDVYFLVEYVKGIELFDVIRDIGLLNTYDSQFYVASMILILEYLHHQNVIYRDMKPEN 609 Query: 152 ILIDSNGYLKLCDFGFCKVLK------KKTWTLCGTPEYLAPEVITSKGYSFSVDWWALG 205 I++D NGYLKL D G K LK +T+T+ GTP Y+APE+I KGY+ VD W++G Sbjct: 610 IMVDENGYLKLIDLGTAKFLKGRHGLGNRTFTIIGTPHYMAPEIICGKGYNCYVDLWSVG 669 Query: 206 DLSFEMEAGHPPF--FASDPNKLYEKVLVGSYKCPENM-SPECKNLLKGLLQVDPSKRIG 262 +E G PF A DP ++YE ++ P + + K L+ LL P R+G Sbjct: 670 ICLYEFMCGMVPFGEEAEDPYEIYEDIIKKEINYPSYLKDKKAKKLMDQLLSRVPEVRLG 729 Query: 263 SLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296 G +KS+ WF DW + ++L P++P Sbjct: 730 ---GSYQTLKSNPWFENFDWDKLLDKELKGPYIP 760 >UniRef50_A2EE93 Cluster: AGC family protein kinase; n=1; Trichomonas vaginalis G3|Rep: AGC family protein kinase - Trichomonas vaginalis G3 Length = 435 Score = 202 bits (492), Expect = 1e-50 Identities = 100/296 (33%), Positives = 168/296 (56%), Gaps = 10/296 (3%) Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78 T+D+F I+ +G G +G+V L IT +A+K V+K+ ++ + + E+ IL Sbjct: 116 TIDEFTIICTLGRGYFGKVLLCEHNITHDVYAIKTVKKARIMNEHKLHTIFAERNILSVS 175 Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138 PF+VT+ AF+ + Y L Y+ GG +F ++Q S +FY ++V LAL+YLH Sbjct: 176 HHPFIVTMYFAFQTDKKFYIGLEYVPGGALFRFLQIGRAMKISEVRFYVAEVALALDYLH 235 Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK-----TWTLCGTPEYLAPEVITSK 193 +++RD+K EN+L+ +G++KL DFG K + +K T T CGT EYL+PE+I+ K Sbjct: 236 SKGILYRDLKLENVLLCQDGHVKLTDFGLSKFVVEKGNYQQTSTFCGTNEYLSPEMISDK 295 Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253 Y F +DWW LG ++E PF+ + KLY +L + P++ KN ++ LL Sbjct: 296 PYGFEIDWWTLGVFTYEFLFTETPFYDKNLKKLYNNILTKEPRFPKDTPSVVKNFIRRLL 355 Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309 +PSKR E+K+ +F+ ++W +++++L P++P + +NF E Sbjct: 356 NKEPSKR-----PTFEELKNDPFFDNINWDDVYNKRLKPPYIPKQVTGRRATNFGE 406 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.322 0.141 0.439 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 401,309,603 Number of Sequences: 1657284 Number of extensions: 17487639 Number of successful extensions: 62156 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 8870 Number of HSP's successfully gapped in prelim test: 2513 Number of HSP's that attempted gapping in prelim test: 37407 Number of HSP's gapped (non-prelim): 14546 length of query: 330 length of database: 575,637,011 effective HSP length: 101 effective length of query: 229 effective length of database: 408,251,327 effective search space: 93489553883 effective search space used: 93489553883 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.9 bits) S2: 73 (33.5 bits)
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