Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000982-TA|BGIBMGA000982-PA|IPR002290|Serine/threonine
protein kinase, IPR000961|Protein kinase, C-terminal,
IPR008271|Serine/threonine protein kinase, active site,
IPR000719|Protein kinase, IPR011009|Protein kinase-like
(330 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 363 e-100
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 363 e-100
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 363 e-100
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 363 e-100
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 362 1e-99
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 362 1e-99
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 362 1e-99
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 362 1e-99
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 362 1e-99
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 362 1e-99
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 350 5e-96
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 350 5e-96
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 350 5e-96
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 350 5e-96
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 350 5e-96
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 345 1e-94
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 303 5e-82
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 303 5e-82
AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase, cAMP-d... 284 3e-76
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 278 2e-74
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 278 2e-74
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 278 2e-74
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 278 2e-74
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 278 2e-74
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 272 1e-72
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 272 1e-72
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 272 1e-72
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 272 1e-72
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 272 1e-72
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 272 1e-72
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 272 1e-72
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 272 1e-72
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 272 1e-72
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 272 1e-72
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 272 1e-72
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 272 1e-72
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 270 5e-72
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 266 1e-70
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 266 1e-70
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 266 1e-70
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 265 2e-70
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 265 2e-70
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 265 2e-70
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 265 2e-70
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 265 2e-70
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 265 2e-70
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 265 2e-70
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 265 2e-70
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 265 2e-70
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 265 2e-70
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 265 2e-70
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 265 2e-70
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 265 2e-70
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 258 3e-68
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 258 3e-68
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 258 3e-68
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 258 3e-68
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 252 2e-66
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 250 4e-66
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 250 5e-66
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 250 5e-66
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 250 5e-66
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 250 5e-66
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 250 5e-66
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 250 5e-66
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 250 5e-66
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 250 5e-66
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 248 2e-65
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 248 2e-65
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 248 2e-65
Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 246 6e-65
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 246 6e-65
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 246 6e-65
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 246 6e-65
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 246 6e-65
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 246 6e-65
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 245 1e-64
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 244 3e-64
Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 243 8e-64
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 243 8e-64
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 241 2e-63
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 241 2e-63
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 241 2e-63
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 241 2e-63
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 240 4e-63
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 239 1e-62
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 232 1e-60
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 232 1e-60
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 232 1e-60
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 232 1e-60
BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein. 232 1e-60
BC028079-1|AAH28079.1| 556|Homo sapiens Unknown (protein for IM... 232 1e-60
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 232 1e-60
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 232 1e-60
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 232 1e-60
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 229 1e-59
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 229 1e-59
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 229 1e-59
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 229 1e-59
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 229 1e-59
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 229 1e-59
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 229 1e-59
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 229 1e-59
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 229 1e-59
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 228 2e-59
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 228 2e-59
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 228 2e-59
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 228 2e-59
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 228 2e-59
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 228 2e-59
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 228 2e-59
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 228 2e-59
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 227 4e-59
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 227 6e-59
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 227 6e-59
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 227 6e-59
AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase, cAMP-de... 226 1e-58
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 225 2e-58
BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated ... 224 3e-58
AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated ... 224 3e-58
AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated ... 224 3e-58
AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated ... 224 3e-58
AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated ... 224 3e-58
AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated ... 224 3e-58
AL358075-6|CAI21706.1| 792|Homo sapiens microtubule associated ... 224 3e-58
AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated ... 224 3e-58
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 223 5e-58
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 223 5e-58
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 223 5e-58
BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein. 223 5e-58
BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein. 223 5e-58
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 223 5e-58
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 223 5e-58
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 223 5e-58
AB047005-1|BAB40778.1| 1734|Homo sapiens MAST205 protein. 223 5e-58
AB018350-1|BAA34527.2| 1329|Homo sapiens KIAA0807 protein protein. 223 5e-58
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 222 1e-57
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 222 1e-57
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 222 1e-57
AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase, cAMP-d... 220 5e-57
AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human seri... 220 5e-57
AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein. 220 5e-57
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 219 8e-57
AY830839-1|AAW52510.1| 2434|Homo sapiens serine/threonine protei... 219 1e-56
AB002301-1|BAA20762.1| 2137|Homo sapiens KIAA0303 protein. 219 1e-56
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 218 2e-56
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 218 2e-56
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 218 2e-56
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 218 2e-56
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 218 3e-56
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 218 3e-56
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 218 3e-56
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 217 3e-56
M80335-1|AAA60094.1| 207|Homo sapiens protein kinase A-alpha pr... 217 4e-56
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 217 6e-56
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 217 6e-56
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 217 6e-56
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 217 6e-56
BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6 ki... 217 6e-56
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 217 6e-56
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 217 6e-56
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 217 6e-56
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 216 8e-56
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 216 8e-56
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 216 1e-55
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 216 1e-55
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 215 1e-55
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 215 1e-55
AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase, cAMP-de... 215 1e-55
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 215 2e-55
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 215 2e-55
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 215 2e-55
X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein ... 214 4e-55
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 212 1e-54
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 212 2e-54
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 212 2e-54
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 212 2e-54
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 212 2e-54
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 212 2e-54
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 212 2e-54
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 212 2e-54
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 212 2e-54
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 210 7e-54
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 210 7e-54
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 210 7e-54
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 210 7e-54
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 210 7e-54
AL590822-6|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 210 7e-54
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 210 7e-54
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 209 9e-54
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 209 1e-53
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 209 1e-53
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 209 1e-53
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 209 1e-53
AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein. 208 3e-53
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 206 6e-53
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 206 6e-53
AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta ... 206 6e-53
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 206 6e-53
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 204 3e-52
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 204 4e-52
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 204 4e-52
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 204 4e-52
BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein. 203 6e-52
AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein. 203 6e-52
AL022329-1|CAB45657.1| 688|Homo sapiens adrenergic, beta, recep... 203 6e-52
X69117-1|CAA48870.1| 688|Homo sapiens beta-adrenergic kinase 2 ... 203 8e-52
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 203 8e-52
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 202 2e-51
AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase, cAMP-de... 201 2e-51
Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma pr... 200 4e-51
BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma... 200 4e-51
AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma ... 200 4e-51
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 200 7e-51
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 200 7e-51
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 200 7e-51
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 200 7e-51
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 200 7e-51
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 200 7e-51
U08438-1|AAB60689.1| 689|Homo sapiens beta-adrenergic receptor ... 199 1e-50
M80776-1|AAA58391.1| 689|Homo sapiens receptor kinase protein. 199 1e-50
BC090863-1|AAH90863.1| 689|Homo sapiens ADRBK1 protein protein. 199 1e-50
BC037963-1|AAH37963.1| 689|Homo sapiens adrenergic, beta, recep... 199 1e-50
X61157-1|CAA43470.1| 689|Homo sapiens beta-adrenergic receptor ... 198 3e-50
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 197 4e-50
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 193 6e-49
BC048261-1|AAH48261.1| 492|Homo sapiens CDC42BPB protein protein. 193 6e-49
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 193 6e-49
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 193 6e-49
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 193 6e-49
BC032709-1|AAH32709.1| 344|Homo sapiens Unknown (protein for IM... 192 1e-48
U59305-1|AAB37126.1| 496|Homo sapiens ser-thr protein kinase PK... 186 7e-47
AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 186 7e-47
AL627308-4|CAH71338.1| 1638|Homo sapiens CDC42 binding protein k... 186 7e-47
AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 186 7e-47
AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 186 7e-47
AL451047-2|CAH71184.1| 1638|Homo sapiens CDC42 binding protein k... 186 7e-47
AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 186 7e-47
AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 186 7e-47
AL353689-8|CAI19110.1| 1638|Homo sapiens CDC42 binding protein k... 186 7e-47
AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 186 7e-47
AJ518976-1|CAD57746.1| 1638|Homo sapiens CDC42 binding protein k... 186 7e-47
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 186 7e-47
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 186 7e-47
AY648038-1|AAT67172.1| 1551|Homo sapiens myotonic dystrophy kina... 184 3e-46
S72883-1|AAB31800.1| 625|Homo sapiens myotonin protein kinase p... 184 5e-46
M94203-1|AAA64884.1| 582|Homo sapiens protein kinase protein. 184 5e-46
L19268-1|AAA36206.1| 624|Homo sapiens protein kinase protein. 184 5e-46
L08835-5|AAC14450.1| 530|Homo sapiens myotonic dystrophy kinase... 184 5e-46
L08835-4|AAC14451.1| 535|Homo sapiens myotonic dystrophy kinase... 184 5e-46
L08835-3|AAC14448.1| 624|Homo sapiens myotonic dystrophy kinase... 184 5e-46
L08835-2|AAC14449.1| 629|Homo sapiens myotonic dystrophy kinase... 184 5e-46
L00727-5|AAA75237.1| 545|Homo sapiens myotonin-protein kinase, ... 184 5e-46
L00727-3|AAA75239.1| 634|Homo sapiens myotonin-protein kinase, ... 184 5e-46
L00727-2|AAA75238.1| 609|Homo sapiens myotonin-protein kinase, ... 184 5e-46
L00727-1|AAA75236.1| 639|Homo sapiens myotonin-protein kinase, ... 184 5e-46
BC062553-1|AAH62553.1| 629|Homo sapiens DMPK protein protein. 184 5e-46
BC026328-1|AAH26328.1| 655|Homo sapiens DMPK protein protein. 184 5e-46
AY166586-1|AAN86031.1| 1638|Homo sapiens CDC42-binding protein k... 184 5e-46
AB209363-1|BAD92600.1| 672|Homo sapiens myotonic dystrophy prot... 184 5e-46
BC038238-1|AAH38238.1| 414|Homo sapiens serine/threonine kinase... 179 1e-44
AJ250839-1|CAB76471.1| 414|Homo sapiens serine/threonine protei... 179 1e-44
AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein. 179 1e-44
AF208004-1|AAG35720.1| 181|Homo sapiens cAMP-dependent protein ... 174 4e-43
AC005793-1|AAC62830.1| 593|Homo sapiens KIAA0561 protein [AA 1-... 170 7e-42
AY098866-1|AAM21719.1| 486|Homo sapiens PKE protein kinase prot... 167 4e-41
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 167 4e-41
AL590105-1|CAI13011.1| 486|Homo sapiens protein kinase (PKE) pr... 167 4e-41
AL512622-1|CAI12181.1| 486|Homo sapiens protein kinase (PKE) pr... 167 4e-41
AL450063-5|CAI16848.1| 186|Homo sapiens protein kinase, cAMP-de... 167 4e-41
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 166 8e-41
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 166 8e-41
AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting ... 165 2e-40
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 163 1e-39
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 163 1e-39
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 163 1e-39
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 163 1e-39
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 163 1e-39
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 161 3e-39
AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 ki... 160 5e-39
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 160 7e-39
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 160 7e-39
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 160 7e-39
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 160 7e-39
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 160 7e-39
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 160 7e-39
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 160 7e-39
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 160 7e-39
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 160 7e-39
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 160 7e-39
AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha... 160 7e-39
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 160 7e-39
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 160 7e-39
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 159 9e-39
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 159 9e-39
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 159 9e-39
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 159 9e-39
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 159 9e-39
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 159 9e-39
U63973-1|AAB05929.1| 563|Homo sapiens rhodopsin kinase protein. 159 1e-38
L77503-1|AAG50439.1| 563|Homo sapiens rhodopsin kinase protein. 159 1e-38
L77502-1|AAT00534.2| 563|Homo sapiens rhodopsin kinase protein. 159 1e-38
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 159 2e-38
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 159 2e-38
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 159 2e-38
U00686-1|AAA03565.1| 544|Homo sapiens putative novel receptor k... 158 2e-38
L16862-1|AAA60175.1| 576|Homo sapiens G protein-coupled recepto... 158 2e-38
BC009277-1|AAH09277.1| 576|Homo sapiens G protein-coupled recep... 158 2e-38
AF040752-1|AAC09274.1| 560|Homo sapiens G protein-coupled recep... 158 2e-38
AF040751-1|AAC09273.1| 589|Homo sapiens G protein-coupled recep... 158 2e-38
L00727-6|AAA75240.1| 540|Homo sapiens myotonin-protein kinase, ... 158 3e-38
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 157 4e-38
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 157 5e-38
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 157 5e-38
BC017272-1|AAH17272.1| 589|Homo sapiens G protein-coupled recep... 157 7e-38
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 154 4e-37
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 154 4e-37
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 154 4e-37
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 154 4e-37
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 154 4e-37
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 154 4e-37
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 153 6e-37
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 153 6e-37
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 153 6e-37
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 153 8e-37
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 153 8e-37
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 153 8e-37
AY358353-1|AAQ88719.1| 364|Homo sapiens HSA250839 protein. 153 8e-37
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 153 8e-37
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 153 8e-37
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 153 8e-37
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 153 8e-37
X98118-1|CAA66802.1| 532|Homo sapiens G protein-coupled recepto... 153 1e-36
X97881-1|CAA66470.1| 578|Homo sapiens G-protein coupled recepto... 153 1e-36
X97880-1|CAA66469.1| 546|Homo sapiens G-protein coupled recepto... 153 1e-36
X97879-1|CAA66468.1| 500|Homo sapiens G-protein coupled recepto... 153 1e-36
U33056-1|AAC50408.1| 532|Homo sapiens G protein-coupled recepto... 153 1e-36
U33055-1|AAC50407.1| 546|Homo sapiens G protein-coupled recepto... 153 1e-36
U33054-1|AAC50406.1| 578|Homo sapiens G protein-coupled recepto... 153 1e-36
L03718-1|AAB04045.1| 500|Homo sapiens G protein-coupled recepto... 153 1e-36
BC117320-1|AAI17321.1| 578|Homo sapiens G protein-coupled recep... 153 1e-36
AK223581-1|BAD97301.1| 500|Homo sapiens G protein-coupled recep... 153 1e-36
U33168-4|AAC50412.1| 500|Homo sapiens G protein-coupled recepto... 152 1e-36
U33168-3|AAC50409.1| 546|Homo sapiens G protein-coupled recepto... 152 1e-36
U33168-2|AAC50411.1| 532|Homo sapiens G protein-coupled recepto... 152 1e-36
U33168-1|AAC50410.1| 578|Homo sapiens G protein-coupled recepto... 152 1e-36
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 152 1e-36
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 152 2e-36
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 152 2e-36
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 152 2e-36
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 152 2e-36
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 152 2e-36
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 152 2e-36
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 152 2e-36
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 152 2e-36
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 152 2e-36
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 152 2e-36
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 152 2e-36
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 152 2e-36
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 151 3e-36
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 151 3e-36
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 151 3e-36
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 151 3e-36
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 151 4e-36
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 151 4e-36
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 151 4e-36
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 151 4e-36
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 151 4e-36
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 151 4e-36
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 151 4e-36
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 151 4e-36
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 151 4e-36
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 151 4e-36
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 151 4e-36
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 151 4e-36
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 151 4e-36
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 150 6e-36
Y12337-1|CAA73006.1| 289|Homo sapiens myotonic dystrophy protei... 150 8e-36
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 150 8e-36
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 149 1e-35
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 149 1e-35
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 149 2e-35
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 149 2e-35
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 148 2e-35
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 148 2e-35
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 147 5e-35
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 147 5e-35
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 147 5e-35
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 147 5e-35
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 147 5e-35
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 147 5e-35
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 146 9e-35
L15388-1|AAA58620.1| 590|Homo sapiens G protein-coupled recepto... 146 9e-35
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 146 9e-35
BC064506-1|AAH64506.1| 590|Homo sapiens G protein-coupled recep... 146 9e-35
AL713896-5|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 146 9e-35
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 146 9e-35
AL713896-3|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 146 9e-35
AL713896-2|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 146 9e-35
AL596247-5|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 146 9e-35
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 146 9e-35
AL596247-3|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 146 9e-35
AL596247-2|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 146 9e-35
AL583824-2|CAI16759.1| 590|Homo sapiens G protein-coupled recep... 146 9e-35
AL355861-4|CAI15804.1| 590|Homo sapiens G protein-coupled recep... 146 9e-35
AL355273-2|CAI16487.1| 590|Homo sapiens G protein-coupled recep... 146 9e-35
AF439409-1|AAL48216.1| 553|Homo sapiens G-protein-coupled recep... 146 9e-35
AF282269-1|AAL33880.1| 553|Homo sapiens G protein-coupled recep... 146 9e-35
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 146 9e-35
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 146 9e-35
BC001737-1|AAH01737.1| 201|Homo sapiens Unknown (protein for IM... 146 1e-34
AL450063-4|CAI16847.1| 175|Homo sapiens protein kinase, cAMP-de... 146 1e-34
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 145 2e-34
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 145 2e-34
BC045760-1|AAH45760.1| 369|Homo sapiens STK32C protein protein. 144 5e-34
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 144 5e-34
AL512622-5|CAI12187.1| 369|Homo sapiens protein kinase (PKE) pr... 144 5e-34
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 144 5e-34
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 143 7e-34
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 142 2e-33
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 142 2e-33
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 142 2e-33
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 142 2e-33
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 142 2e-33
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 142 2e-33
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 142 2e-33
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 142 2e-33
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 142 2e-33
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 142 2e-33
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 142 2e-33
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 142 2e-33
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 142 2e-33
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 142 2e-33
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 142 2e-33
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 141 4e-33
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 141 4e-33
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 141 4e-33
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 141 4e-33
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 141 4e-33
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 141 4e-33
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 141 4e-33
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 141 4e-33
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 141 4e-33
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 141 4e-33
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 141 4e-33
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 141 4e-33
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 141 4e-33
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 141 4e-33
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 141 4e-33
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 141 4e-33
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 141 4e-33
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 140 5e-33
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 140 5e-33
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 140 5e-33
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 140 6e-33
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 139 1e-32
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 139 1e-32
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 139 1e-32
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 139 1e-32
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 139 1e-32
AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 139 1e-32
AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 139 1e-32
AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 139 1e-32
AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 139 1e-32
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 139 1e-32
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 139 1e-32
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 139 1e-32
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 139 1e-32
Z98752-6|CAI42313.1| 198|Homo sapiens serum/glucocorticoid regu... 138 2e-32
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 138 3e-32
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 138 3e-32
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 138 3e-32
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 138 3e-32
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 138 3e-32
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 138 3e-32
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 138 3e-32
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 137 4e-32
AY702977-1|AAU29340.1| 643|Homo sapiens protein kinase C theta ... 137 4e-32
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 137 4e-32
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 137 6e-32
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 137 6e-32
BC028603-1|AAH28603.1| 464|Homo sapiens serine/threonine kinase... 137 6e-32
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 137 6e-32
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 137 6e-32
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 137 6e-32
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 137 6e-32
AB023182-1|BAA76809.2| 489|Homo sapiens KIAA0965 protein protein. 137 6e-32
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 136 8e-32
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 136 8e-32
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 136 8e-32
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 136 8e-32
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 136 8e-32
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 136 8e-32
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 136 8e-32
Z85986-3|CAB39180.1| 465|Homo sapiens serine/threonine kinase 3... 136 1e-31
Z35102-1|CAA84485.1| 465|Homo sapiens Ndr protein kinase protein. 136 1e-31
BC095413-1|AAH95413.1| 465|Homo sapiens serine/threonine kinase... 136 1e-31
BC012085-1|AAH12085.1| 465|Homo sapiens serine/threonine kinase... 136 1e-31
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 136 1e-31
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 135 2e-31
>X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for
cAMP-dependent protein kinase catalytic subunit type
alpha (EC 2.7.1.37). ).
Length = 351
Score = 363 bits (894), Expect = e-100
Identities = 158/328 (48%), Positives = 232/328 (70%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ +D F+ +K +G G++G V LV+ K T ++AMK+++K VV+
Sbjct: 24 KEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKL 83
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ +FKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTP 203
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S
Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS 263
Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302
+ K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P PG
Sbjct: 264 SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPG 323
Query: 303 DTSNFPEIPQPKLRKVSKYLYEEEFAEF 330
DTSNF + + ++R +EF+EF
Sbjct: 324 DTSNFDDYEEEEIRVSINEKCGKEFSEF 351
>DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 363 bits (894), Expect = e-100
Identities = 158/328 (48%), Positives = 232/328 (70%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ +D F+ +K +G G++G V LV+ K T ++AMK+++K VV+
Sbjct: 24 KEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKL 83
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ +FKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTP 203
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S
Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS 263
Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302
+ K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P PG
Sbjct: 264 SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPG 323
Query: 303 DTSNFPEIPQPKLRKVSKYLYEEEFAEF 330
DTSNF + + ++R +EF+EF
Sbjct: 324 DTSNFDDYEEEEIRVSINEKCGKEFSEF 351
>BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 363 bits (894), Expect = e-100
Identities = 158/328 (48%), Positives = 232/328 (70%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ +D F+ +K +G G++G V LV+ K T ++AMK+++K VV+
Sbjct: 24 KEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKL 83
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ +FKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTP 203
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S
Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS 263
Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302
+ K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P PG
Sbjct: 264 SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPG 323
Query: 303 DTSNFPEIPQPKLRKVSKYLYEEEFAEF 330
DTSNF + + ++R +EF+EF
Sbjct: 324 DTSNFDDYEEEEIRVSINEKCGKEFSEF 351
>BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 363 bits (894), Expect = e-100
Identities = 158/328 (48%), Positives = 232/328 (70%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ +D F+ +K +G G++G V LV+ K T ++AMK+++K VV+
Sbjct: 24 KEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKL 83
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ +FKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTP 203
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S
Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS 263
Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302
+ K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P PG
Sbjct: 264 SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPG 323
Query: 303 DTSNFPEIPQPKLRKVSKYLYEEEFAEF 330
DTSNF + + ++R +EF+EF
Sbjct: 324 DTSNFDDYEEEEIRVSINEKCGKEFSEF 351
>M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein
kinase catalytic subunit protein.
Length = 351
Score = 362 bits (890), Expect = 1e-99
Identities = 159/328 (48%), Positives = 231/328 (70%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 24 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 83
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 203
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S
Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS 263
Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302
+ K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P G
Sbjct: 264 SDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSG 323
Query: 303 DTSNFPEIPQPKLRKVSKYLYEEEFAEF 330
DTSNF + + +R +EF EF
Sbjct: 324 DTSNFDDYEEEDIRVSITEKCAKEFGEF 351
>DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 362 bits (890), Expect = 1e-99
Identities = 159/328 (48%), Positives = 231/328 (70%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 71 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 130
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 131 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 190
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 191 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 250
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S
Sbjct: 251 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS 310
Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302
+ K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P G
Sbjct: 311 SDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSG 370
Query: 303 DTSNFPEIPQPKLRKVSKYLYEEEFAEF 330
DTSNF + + +R +EF EF
Sbjct: 371 DTSNFDDYEEEDIRVSITEKCAKEFGEF 398
>BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 362 bits (890), Expect = 1e-99
Identities = 159/328 (48%), Positives = 231/328 (70%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 24 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 83
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYL+ ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 144 ARFYAAQIVLTFEYLNSLDIIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 203
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P N S
Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSNFS 263
Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302
+ K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P G
Sbjct: 264 SDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSG 323
Query: 303 DTSNFPEIPQPKLRKVSKYLYEEEFAEF 330
DTSNF + + +R +EF EF
Sbjct: 324 DTSNFDDYEEEDIRVSITEKCAKEFGEF 351
>AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 362 bits (890), Expect = 1e-99
Identities = 159/328 (48%), Positives = 231/328 (70%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 71 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 130
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 131 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 190
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 191 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 250
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S
Sbjct: 251 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS 310
Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302
+ K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P G
Sbjct: 311 SDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSG 370
Query: 303 DTSNFPEIPQPKLRKVSKYLYEEEFAEF 330
DTSNF + + +R +EF EF
Sbjct: 371 DTSNFDDYEEEDIRVSITEKCAKEFGEF 398
>AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 362 bits (890), Expect = 1e-99
Identities = 159/328 (48%), Positives = 231/328 (70%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 24 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 83
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 203
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S
Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS 263
Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302
+ K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P G
Sbjct: 264 SDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSG 323
Query: 303 DTSNFPEIPQPKLRKVSKYLYEEEFAEF 330
DTSNF + + +R +EF EF
Sbjct: 324 DTSNFDDYEEEDIRVSITEKCAKEFGEF 351
>AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 362 bits (890), Expect = 1e-99
Identities = 159/328 (48%), Positives = 231/328 (70%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 24 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 83
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 203
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S
Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS 263
Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPG 302
+ K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P G
Sbjct: 264 SDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSG 323
Query: 303 DTSNFPEIPQPKLRKVSKYLYEEEFAEF 330
DTSNF + + +R +EF EF
Sbjct: 324 DTSNFDDYEEEDIRVSITEKCAKEFGEF 351
>M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A
gamma-subunit protein.
Length = 360
Score = 350 bits (860), Expect = 5e-96
Identities = 155/326 (47%), Positives = 227/326 (69%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
DF ++ + + D F+ ++ +G G++G V LVR + T ++AMK++ K VV+
Sbjct: 35 DFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQ 94
Query: 65 AKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTK 124
+H++ EK+ILQ I FPF+V L +FKDN YLY ++ Y+ GGEMF+ +Q+ G FS+
Sbjct: 95 VEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHAC 154
Query: 125 FYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEY 184
FYA+QV+LA++YLH +++HRD+KPEN+LID GYL++ DFGF K +K +TWTLCGTPEY
Sbjct: 155 FYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEY 214
Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPE 244
LAPE+I SKGY+ +VDWWALG L +EM G PPF+A P ++YEK++ G + P +S +
Sbjct: 215 LAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSD 274
Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304
K+LL+ LLQVD +KR G+L+ G+ +IK+H WF W AI+ +K+ APF+P + PGD
Sbjct: 275 LKDLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDA 334
Query: 305 SNFPEIPQPKLRKVSKYLYEEEFAEF 330
SNF + + +LR +EF+EF
Sbjct: 335 SNFDDYEEEELRISINEKCAKEFSEF 360
>DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 350 bits (860), Expect = 5e-96
Identities = 155/326 (47%), Positives = 227/326 (69%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
DF ++ + + D F+ ++ +G G++G V LVR + T ++AMK++ K VV+
Sbjct: 26 DFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQ 85
Query: 65 AKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTK 124
+H++ EK+ILQ I FPF+V L +FKDN YLY ++ Y+ GGEMF+ +Q+ G FS+
Sbjct: 86 VEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHAC 145
Query: 125 FYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEY 184
FYA+QV+LA++YLH +++HRD+KPEN+LID GYL++ DFGF K +K +TWTLCGTPEY
Sbjct: 146 FYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEY 205
Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPE 244
LAPE+I SKGY+ +VDWWALG L +EM G PPF+A P ++YEK++ G + P +S +
Sbjct: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSD 265
Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304
K+LL+ LLQVD +KR G+L+ G+ +IK+H WF W AI+ +K+ APF+P + PGD
Sbjct: 266 LKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDA 325
Query: 305 SNFPEIPQPKLRKVSKYLYEEEFAEF 330
SNF + + +LR +EF+EF
Sbjct: 326 SNFDDYEEEELRISINEKCAKEFSEF 351
>BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 350 bits (860), Expect = 5e-96
Identities = 155/326 (47%), Positives = 227/326 (69%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
DF ++ + + D F+ ++ +G G++G V LVR + T ++AMK++ K VV+
Sbjct: 26 DFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQ 85
Query: 65 AKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTK 124
+H++ EK+ILQ I FPF+V L +FKDN YLY ++ Y+ GGEMF+ +Q+ G FS+
Sbjct: 86 VEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHAC 145
Query: 125 FYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEY 184
FYA+QV+LA++YLH +++HRD+KPEN+LID GYL++ DFGF K +K +TWTLCGTPEY
Sbjct: 146 FYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEY 205
Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPE 244
LAPE+I SKGY+ +VDWWALG L +EM G PPF+A P ++YEK++ G + P +S +
Sbjct: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSD 265
Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304
K+LL+ LLQVD +KR G+L+ G+ +IK+H WF W AI+ +K+ APF+P + PGD
Sbjct: 266 LKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDA 325
Query: 305 SNFPEIPQPKLRKVSKYLYEEEFAEF 330
SNF + + +LR +EF+EF
Sbjct: 326 SNFDDYEEEELRISINEKCPKEFSEF 351
>AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 350 bits (860), Expect = 5e-96
Identities = 155/326 (47%), Positives = 227/326 (69%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
DF ++ + + D F+ ++ +G G++G V LVR + T ++AMK++ K VV+
Sbjct: 26 DFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQ 85
Query: 65 AKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTK 124
+H++ EK+ILQ I FPF+V L +FKDN YLY ++ Y+ GGEMF+ +Q+ G FS+
Sbjct: 86 VEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHAC 145
Query: 125 FYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEY 184
FYA+QV+LA++YLH +++HRD+KPEN+LID GYL++ DFGF K +K +TWTLCGTPEY
Sbjct: 146 FYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEY 205
Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPE 244
LAPE+I SKGY+ +VDWWALG L +EM G PPF+A P ++YEK++ G + P +S +
Sbjct: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSD 265
Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304
K+LL+ LLQVD +KR G+L+ G+ +IK+H WF W AI+ +K+ APF+P + PGD
Sbjct: 266 LKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDA 325
Query: 305 SNFPEIPQPKLRKVSKYLYEEEFAEF 330
SNF + + +LR +EF+EF
Sbjct: 326 SNFDDYEEEELRISINEKCAKEFSEF 351
>AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein
kinase gamma isoform protein.
Length = 351
Score = 350 bits (860), Expect = 5e-96
Identities = 155/326 (47%), Positives = 227/326 (69%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
DF ++ + + D F+ ++ +G G++G V LVR + T ++AMK++ K VV+
Sbjct: 26 DFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQ 85
Query: 65 AKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTK 124
+H++ EK+ILQ I FPF+V L +FKDN YLY ++ Y+ GGEMF+ +Q+ G FS+
Sbjct: 86 VEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHAC 145
Query: 125 FYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEY 184
FYA+QV+LA++YLH +++HRD+KPEN+LID GYL++ DFGF K +K +TWTLCGTPEY
Sbjct: 146 FYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEY 205
Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPE 244
LAPE+I SKGY+ +VDWWALG L +EM G PPF+A P ++YEK++ G + P +S +
Sbjct: 206 LAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSD 265
Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304
K+LL+ LLQVD +KR G+L+ G+ +IK+H WF W AI+ +K+ APF+P + PGD
Sbjct: 266 LKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDA 325
Query: 305 SNFPEIPQPKLRKVSKYLYEEEFAEF 330
SNF + + +LR +EF+EF
Sbjct: 326 SNFDDYEEEELRISINEKCAKEFSEF 351
>AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein
kinase catalytic subunit beta isoform 2 variant protein.
Length = 365
Score = 345 bits (849), Expect = 1e-94
Identities = 148/294 (50%), Positives = 216/294 (73%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 50 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 109
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 110 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 169
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 170 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 229
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMS 242
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G + P + S
Sbjct: 230 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFS 289
Query: 243 PECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296
+ K+LL+ LLQVD +KR G+LK G+ +IK+H WF DW AI+ +K+ APF+P
Sbjct: 290 SDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 343
>X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein.
Length = 358
Score = 303 bits (744), Expect = 5e-82
Identities = 134/301 (44%), Positives = 201/301 (66%), Gaps = 2/301 (0%)
Query: 12 DAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILE 71
+ P+Y ++ DFD + +G G +G V LV++K + A+KV+ V+ +H+ E
Sbjct: 40 EPPVY--SLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNE 97
Query: 72 KKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVI 131
K +L+ + PF++ L + D +LY ++ Y+ GGE+F+Y++ G FS + FY++++I
Sbjct: 98 KSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEII 157
Query: 132 LALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVIT 191
A+EYLH E+V+RD+KPENIL+D +G++KL DFGF K L +TWTLCGTPEYLAPEVI
Sbjct: 158 CAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQ 217
Query: 192 SKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKG 251
SKG+ +VDWWALG L FEM +G PPFF +P +Y+K+L G P ++ K+L+K
Sbjct: 218 SKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKK 277
Query: 252 LLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIP 311
LL VD ++R+G++K G ++K H WF +DW+A+ +KL P VP + GDTSNF P
Sbjct: 278 LLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYP 337
Query: 312 Q 312
+
Sbjct: 338 E 338
>BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linked
protein.
Length = 358
Score = 303 bits (744), Expect = 5e-82
Identities = 134/301 (44%), Positives = 201/301 (66%), Gaps = 2/301 (0%)
Query: 12 DAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILE 71
+ P+Y ++ DFD + +G G +G V LV++K + A+KV+ V+ +H+ E
Sbjct: 40 EPPVY--SLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNE 97
Query: 72 KKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVI 131
K +L+ + PF++ L + D +LY ++ Y+ GGE+F+Y++ G FS + FY++++I
Sbjct: 98 KSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEII 157
Query: 132 LALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVIT 191
A+EYLH E+V+RD+KPENIL+D +G++KL DFGF K L +TWTLCGTPEYLAPEVI
Sbjct: 158 CAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQ 217
Query: 192 SKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKG 251
SKG+ +VDWWALG L FEM +G PPFF +P +Y+K+L G P ++ K+L+K
Sbjct: 218 SKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKK 277
Query: 252 LLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIP 311
LL VD ++R+G++K G ++K H WF +DW+A+ +KL P VP + GDTSNF P
Sbjct: 278 LLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYP 337
Query: 312 Q 312
+
Sbjct: 338 E 338
>AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 321
Score = 284 bits (697), Expect = 3e-76
Identities = 122/240 (50%), Positives = 173/240 (72%)
Query: 91 KDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPE 150
KDN LY ++ Y+ GGEMF+++++ G FS+ +FYA+Q++L EYLH ++++RD+KPE
Sbjct: 82 KDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPE 141
Query: 151 NILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFE 210
N+LID GY+++ DFGF K +K +TWTLCGTPEYLAPE+I SKGY+ +VDWWALG L +E
Sbjct: 142 NLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYE 201
Query: 211 MEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYE 270
M AG+PPFFA P ++YEK++ G + P + S + K+LL+ LLQVD +KR G+LK G+ +
Sbjct: 202 MAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSD 261
Query: 271 IKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPKLRKVSKYLYEEEFAEF 330
IK+H WF DW AI+ +K+ APF+P GDTSNF + + +R +EF EF
Sbjct: 262 IKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 321
Score = 50.8 bits (116), Expect = 6e-06
Identities = 22/54 (40%), Positives = 36/54 (66%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEK 56
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K
Sbjct: 27 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 80
>BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 278 bits (681), Expect = 2e-74
Identities = 118/231 (51%), Positives = 172/231 (74%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 24 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 83
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 203
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG 233
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G
Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 254
>AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 264
Score = 278 bits (681), Expect = 2e-74
Identities = 118/231 (51%), Positives = 172/231 (74%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 30 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 89
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 90 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 149
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 150 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 209
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG 233
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G
Sbjct: 210 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 260
>AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 245
Score = 278 bits (681), Expect = 2e-74
Identities = 118/231 (51%), Positives = 172/231 (74%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 12 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 71
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 72 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 131
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 132 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 191
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG 233
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G
Sbjct: 192 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 242
>AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 278 bits (681), Expect = 2e-74
Identities = 118/231 (51%), Positives = 172/231 (74%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 24 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 83
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 203
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG 233
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G
Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 254
>AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 278 bits (681), Expect = 2e-74
Identities = 118/231 (51%), Positives = 172/231 (74%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 24 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 83
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 84 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 143
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 144 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 203
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG 233
EYLAPE+I SKGY+ +VDWWALG L +EM AG+PPFFA P ++YEK++ G
Sbjct: 204 EYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG 254
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 272 bits (667), Expect = 1e-72
Identities = 119/295 (40%), Positives = 194/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 270 bits (662), Expect = 5e-72
Identities = 119/295 (40%), Positives = 193/295 (65%), Gaps = 3/295 (1%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
KT++DFD +K +G G +G+V LVR+K + Y+AMK+++K V++ ++ H + E ++L+
Sbjct: 143 KTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKN 202
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF+ +L +F+ L F++ Y+ GGE+F ++ + +FS+ T+FY ++++ AL+YL
Sbjct: 203 TRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYL 262
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKG 194
H ++V+RD+K EN++ D +G++K+ DFG CK + T T CGTPEYLAPEV+
Sbjct: 263 HSGKIVYRDLKLENLMRDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
Y +VDWW LG + +EM G PF+ D KL+E +L+ K P +S + K+LL GLL
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLI 382
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP+KR+G EI H++F+G++WQ ++ +KL+ PF P +S DT F E
Sbjct: 383 KDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDE 437
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 266 bits (651), Expect = 1e-70
Identities = 118/294 (40%), Positives = 187/294 (63%), Gaps = 3/294 (1%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DFD +K +G G +G+V LVR+K T Y+AMK++ K V++ ++ H + E ++LQ
Sbjct: 148 TMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNT 207
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+ L AF+ + L F++ Y GGE+F ++ + +F++ +FY ++++ ALEYLH
Sbjct: 208 RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH 267
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKGY 195
+VV+RDIK EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+ Y
Sbjct: 268 SRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDY 327
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+VDWW LG + +EM G PF+ D +L+E +L+ + P +SPE K+LL GLL+
Sbjct: 328 GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKK 387
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP +R+G E+ H +F ++WQ + +KL+ PF P +S DT F +
Sbjct: 388 DPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDD 441
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 266 bits (651), Expect = 1e-70
Identities = 118/294 (40%), Positives = 187/294 (63%), Gaps = 3/294 (1%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DFD +K +G G +G+V LVR+K T Y+AMK++ K V++ ++ H + E ++LQ
Sbjct: 148 TMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNT 207
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+ L AF+ + L F++ Y GGE+F ++ + +F++ +FY ++++ ALEYLH
Sbjct: 208 RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH 267
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKGY 195
+VV+RDIK EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+ Y
Sbjct: 268 SRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDY 327
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+VDWW LG + +EM G PF+ D +L+E +L+ + P +SPE K+LL GLL+
Sbjct: 328 GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKK 387
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP +R+G E+ H +F ++WQ + +KL+ PF P +S DT F +
Sbjct: 388 DPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDD 441
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 266 bits (651), Expect = 1e-70
Identities = 118/294 (40%), Positives = 187/294 (63%), Gaps = 3/294 (1%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DFD +K +G G +G+V LVR+K T Y+AMK++ K V++ ++ H + E ++LQ
Sbjct: 148 TMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNT 207
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+ L AF+ + L F++ Y GGE+F ++ + +F++ +FY ++++ ALEYLH
Sbjct: 208 RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH 267
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKGY 195
+VV+RDIK EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+ Y
Sbjct: 268 SRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDY 327
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+VDWW LG + +EM G PF+ D +L+E +L+ + P +SPE K+LL GLL+
Sbjct: 328 GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKK 387
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
DP +R+G E+ H +F ++WQ + +KL+ PF P +S DT F +
Sbjct: 388 DPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDD 441
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 551
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 552 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 611
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 612 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 669
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 357 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 416
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 417 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 476
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 477 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 536
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 537 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 596
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 597 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 654
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 551
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 552 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 611
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 612 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 669
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 357 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 416
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 417 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 476
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 477 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 536
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 537 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 596
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 597 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 654
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 551
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 552 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 611
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 612 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 669
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 551
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 552 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 611
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 612 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 669
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 345 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 404
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 524
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 525 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 584
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 585 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 642
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 551
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 552 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 611
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 612 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 669
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 345 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 404
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 524
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 525 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 584
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 585 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 642
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 551
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 552 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 611
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 612 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 669
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 345 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 404
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 524
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 525 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 584
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 585 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 642
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 432 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 491
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 492 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 551
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 552 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 611
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 612 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 669
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 265 bits (649), Expect = 2e-70
Identities = 124/298 (41%), Positives = 187/298 (62%), Gaps = 5/298 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTY-HAMKVVEKSVVVERNHAKHLILEKKILQCI 78
+ DF+I+ +G G +G V LV+ K + AMK+++K +V+ +H+ EK+I+Q
Sbjct: 345 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 404
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
F+V L FKD+ YLY ++ GGE++T ++ G F DS T+FY + V+ A YLH
Sbjct: 405 HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLH 464
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPEN+++D GY KL DFGF K + KKTWT CGTPEY+APE+I +KG+
Sbjct: 465 SKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD 524
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVG--SYKCPENMSPECKNLLKGLLQ 254
S D+W+LG L +E+ G PPF DP K Y +L G + P+ ++ NL+K L +
Sbjct: 525 ISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR 584
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQ 312
+PS+R+G+LK G+ +I+ H WF G +W+ + L P +P +SP DTSNF P+
Sbjct: 585 DNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPE 642
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 258 bits (631), Expect = 3e-68
Identities = 118/300 (39%), Positives = 189/300 (63%), Gaps = 4/300 (1%)
Query: 14 PIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKK 73
P + T+++F+ +K +G G +G+V LV++K T Y+AMK+++K V+V ++ H + E +
Sbjct: 141 PKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENR 200
Query: 74 ILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
+LQ + PF+ L +F+ + L F++ Y GGE+F ++ + +FS+ +FY ++++ A
Sbjct: 201 VLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSA 260
Query: 134 LEYLHYCE-VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTL---CGTPEYLAPEV 189
L+YLH + VV+RD+K EN+++D +G++K+ DFG CK K T+ CGTPEYLAPEV
Sbjct: 261 LDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEV 320
Query: 190 ITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLL 249
+ Y +VDWW LG + +EM G PF+ D KL+E +L+ + P + PE K+LL
Sbjct: 321 LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLL 380
Query: 250 KGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
GLL+ DP +R+G EI H +F G+ WQ ++ +KL PF P +S DT F E
Sbjct: 381 SGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDE 440
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 258 bits (631), Expect = 3e-68
Identities = 118/300 (39%), Positives = 189/300 (63%), Gaps = 4/300 (1%)
Query: 14 PIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKK 73
P + T+++F+ +K +G G +G+V LV++K T Y+AMK+++K V+V ++ H + E +
Sbjct: 141 PKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENR 200
Query: 74 ILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
+LQ + PF+ L +F+ + L F++ Y GGE+F ++ + +FS+ +FY ++++ A
Sbjct: 201 VLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSA 260
Query: 134 LEYLHYCE-VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTL---CGTPEYLAPEV 189
L+YLH + VV+RD+K EN+++D +G++K+ DFG CK K T+ CGTPEYLAPEV
Sbjct: 261 LDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEV 320
Query: 190 ITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLL 249
+ Y +VDWW LG + +EM G PF+ D KL+E +L+ + P + PE K+LL
Sbjct: 321 LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLL 380
Query: 250 KGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
GLL+ DP +R+G EI H +F G+ WQ ++ +KL PF P +S DT F E
Sbjct: 381 SGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDE 440
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 258 bits (631), Expect = 3e-68
Identities = 118/300 (39%), Positives = 189/300 (63%), Gaps = 4/300 (1%)
Query: 14 PIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKK 73
P + T+++F+ +K +G G +G+V LV++K T Y+AMK+++K V+V ++ H + E +
Sbjct: 141 PKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENR 200
Query: 74 ILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
+LQ + PF+ L +F+ + L F++ Y GGE+F ++ + +FS+ +FY ++++ A
Sbjct: 201 VLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSA 260
Query: 134 LEYLHYCE-VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTL---CGTPEYLAPEV 189
L+YLH + VV+RD+K EN+++D +G++K+ DFG CK K T+ CGTPEYLAPEV
Sbjct: 261 LDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEV 320
Query: 190 ITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLL 249
+ Y +VDWW LG + +EM G PF+ D KL+E +L+ + P + PE K+LL
Sbjct: 321 LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLL 380
Query: 250 KGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
GLL+ DP +R+G EI H +F G+ WQ ++ +KL PF P +S DT F E
Sbjct: 381 SGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDE 440
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 258 bits (631), Expect = 3e-68
Identities = 118/300 (39%), Positives = 189/300 (63%), Gaps = 4/300 (1%)
Query: 14 PIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKK 73
P + T+++F+ +K +G G +G+V LV++K T Y+AMK+++K V+V ++ H + E +
Sbjct: 141 PKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENR 200
Query: 74 ILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
+LQ + PF+ L +F+ + L F++ Y GGE+F ++ + +FS+ +FY ++++ A
Sbjct: 201 VLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSA 260
Query: 134 LEYLHYCE-VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTL---CGTPEYLAPEV 189
L+YLH + VV+RD+K EN+++D +G++K+ DFG CK K T+ CGTPEYLAPEV
Sbjct: 261 LDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEV 320
Query: 190 ITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLL 249
+ Y +VDWW LG + +EM G PF+ D KL+E +L+ + P + PE K+LL
Sbjct: 321 LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLL 380
Query: 250 KGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
GLL+ DP +R+G EI H +F G+ WQ ++ +KL PF P +S DT F E
Sbjct: 381 SGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDE 440
>X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B
protein.
Length = 417
Score = 252 bits (616), Expect = 2e-66
Identities = 116/300 (38%), Positives = 188/300 (62%), Gaps = 5/300 (1%)
Query: 14 PIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKK 73
P + T+++F+ +K +G G +G+V LV++K T Y+AMK+++K V+V ++ H + E +
Sbjct: 79 PKHRVTMNEFEYLKLLGKGTFGKVILVKEKAT-AYYAMKILKKEVIVAKDEVAHTLTENR 137
Query: 74 ILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
+ Q + PF+ L +F+ + L F++ Y GGE+F ++ + +F++ +FY ++++ A
Sbjct: 138 VQQNSRHPFLTRLKYSFQTHDRLCFVMEYANGGELFFHLSRERVFAEDRARFYGAEIVSA 197
Query: 134 LEYLHYCE-VVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTL---CGTPEYLAPEV 189
L+YLH + VV+RD+K EN+++D +G++K+ DFG CK K T+ CGTPEYLAPEV
Sbjct: 198 LDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEV 257
Query: 190 ITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLL 249
+ Y +VDWW LG + +EM G PF+ D KL+E +L+ + P + PE K+LL
Sbjct: 258 LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLL 317
Query: 250 KGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
GLL+ DP +R+G EI H +F G+ WQ ++ +KL PF P +S DT F E
Sbjct: 318 SGLLKKDPKQRLGGGSEDAKEIMQHRFFTGIVWQHVYEKKLSPPFKPQVTSETDTRYFDE 377
>AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 283
Score = 250 bits (613), Expect = 4e-66
Identities = 113/266 (42%), Positives = 169/266 (63%), Gaps = 4/266 (1%)
Query: 51 MKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFT 110
MK+++K +V+ +H+ EK+I+Q F+V L FKD+ YLY ++ GGE++T
Sbjct: 1 MKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 60
Query: 111 YIQKYGIFSDSLTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV 170
++ G F DS T+FY + V+ A YLH +++RD+KPEN+++D GY KL DFGF K
Sbjct: 61 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 120
Query: 171 L--KKKTWTLCGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYE 228
+ KKTWT CGTPEY+APE+I +KG+ S D+W+LG L +E+ G PPF DP K Y
Sbjct: 121 IGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYN 180
Query: 229 KVLVG--SYKCPENMSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIF 286
+L G + P+ ++ NL+K L + +PS+R+G+LK G+ +I+ H WF G +W+ +
Sbjct: 181 IILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLR 240
Query: 287 HQKLIAPFVPICSSPGDTSNFPEIPQ 312
L P +P +SP DTSNF P+
Sbjct: 241 KGTLTPPIIPSVASPTDTSNFDSFPE 266
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 250 bits (612), Expect = 5e-66
Identities = 119/296 (40%), Positives = 189/296 (63%), Gaps = 6/296 (2%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DF +K IG G++G+V L R K ++A+KV++K ++++ KH++ E+ +L + ++
Sbjct: 192 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 251
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L YI GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 252 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 311
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+V+RD+KPENIL+DS G++ L DFG CK T T CGTPEYLAPEV+ + Y
Sbjct: 312 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 371
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ + ++Y+ +L + N++ ++LL+GLLQ D
Sbjct: 372 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 431
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312
+KR+G+ K EIKSH +F+ ++W + ++K+ PF P S P D +F PE +
Sbjct: 432 TKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTE 486
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 250 bits (612), Expect = 5e-66
Identities = 119/296 (40%), Positives = 189/296 (63%), Gaps = 6/296 (2%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DF +K IG G++G+V L R K ++A+KV++K ++++ KH++ E+ +L + ++
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L YI GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+V+RD+KPENIL+DS G++ L DFG CK T T CGTPEYLAPEV+ + Y
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ + ++Y+ +L + N++ ++LL+GLLQ D
Sbjct: 277 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 336
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312
+KR+G+ K EIKSH +F+ ++W + ++K+ PF P S P D +F PE +
Sbjct: 337 TKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTE 391
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 250 bits (612), Expect = 5e-66
Identities = 119/296 (40%), Positives = 189/296 (63%), Gaps = 6/296 (2%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DF +K IG G++G+V L R K ++A+KV++K ++++ KH++ E+ +L + ++
Sbjct: 192 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 251
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L YI GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 252 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 311
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+V+RD+KPENIL+DS G++ L DFG CK T T CGTPEYLAPEV+ + Y
Sbjct: 312 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 371
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ + ++Y+ +L + N++ ++LL+GLLQ D
Sbjct: 372 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 431
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312
+KR+G+ K EIKSH +F+ ++W + ++K+ PF P S P D +F PE +
Sbjct: 432 TKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTE 486
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 250 bits (612), Expect = 5e-66
Identities = 119/296 (40%), Positives = 189/296 (63%), Gaps = 6/296 (2%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DF +K IG G++G+V L R K ++A+KV++K ++++ KH++ E+ +L + ++
Sbjct: 192 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 251
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L YI GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 252 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 311
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+V+RD+KPENIL+DS G++ L DFG CK T T CGTPEYLAPEV+ + Y
Sbjct: 312 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 371
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ + ++Y+ +L + N++ ++LL+GLLQ D
Sbjct: 372 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 431
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312
+KR+G+ K EIKSH +F+ ++W + ++K+ PF P S P D +F PE +
Sbjct: 432 TKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTE 486
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 250 bits (612), Expect = 5e-66
Identities = 119/296 (40%), Positives = 189/296 (63%), Gaps = 6/296 (2%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DF +K IG G++G+V L R K ++A+KV++K ++++ KH++ E+ +L + ++
Sbjct: 111 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 170
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L YI GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 171 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 230
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+V+RD+KPENIL+DS G++ L DFG CK T T CGTPEYLAPEV+ + Y
Sbjct: 231 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 290
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ + ++Y+ +L + N++ ++LL+GLLQ D
Sbjct: 291 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 350
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312
+KR+G+ K EIKSH +F+ ++W + ++K+ PF P S P D +F PE +
Sbjct: 351 TKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTE 405
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 250 bits (612), Expect = 5e-66
Identities = 119/296 (40%), Positives = 189/296 (63%), Gaps = 6/296 (2%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DF +K IG G++G+V L R K ++A+KV++K ++++ KH++ E+ +L + ++
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L YI GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+V+RD+KPENIL+DS G++ L DFG CK T T CGTPEYLAPEV+ + Y
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ + ++Y+ +L + N++ ++LL+GLLQ D
Sbjct: 277 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 336
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312
+KR+G+ K EIKSH +F+ ++W + ++K+ PF P S P D +F PE +
Sbjct: 337 TKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTE 391
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 250 bits (612), Expect = 5e-66
Identities = 119/296 (40%), Positives = 189/296 (63%), Gaps = 6/296 (2%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DF +K IG G++G+V L R K ++A+KV++K ++++ KH++ E+ +L + ++
Sbjct: 87 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 146
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L YI GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 147 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 206
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+V+RD+KPENIL+DS G++ L DFG CK T T CGTPEYLAPEV+ + Y
Sbjct: 207 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 266
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ + ++Y+ +L + N++ ++LL+GLLQ D
Sbjct: 267 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 326
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312
+KR+G+ K EIKSH +F+ ++W + ++K+ PF P S P D +F PE +
Sbjct: 327 TKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTE 381
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 250 bits (612), Expect = 5e-66
Identities = 119/296 (40%), Positives = 189/296 (63%), Gaps = 6/296 (2%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DF +K IG G++G+V L R K ++A+KV++K ++++ KH++ E+ +L + ++
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L YI GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+V+RD+KPENIL+DS G++ L DFG CK T T CGTPEYLAPEV+ + Y
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ + ++Y+ +L + N++ ++LL+GLLQ D
Sbjct: 277 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 336
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312
+KR+G+ K EIKSH +F+ ++W + ++K+ PF P S P D +F PE +
Sbjct: 337 TKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTE 391
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 248 bits (608), Expect = 2e-65
Identities = 118/296 (39%), Positives = 189/296 (63%), Gaps = 6/296 (2%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DF +K IG G++G+V L R K ++A+KV++K ++++ KH++ E+ +L + ++
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L YI GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+V+RD+KPENIL+DS G++ L DFG CK T T CGTPEYLAPEV+ + Y
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ + ++Y+ +L + N++ ++LL+GLLQ D
Sbjct: 277 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 336
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312
+KR+G+ K EIKSH +F+ ++W + ++K+ PF P S P + +F PE +
Sbjct: 337 TKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNELRHFDPEFTE 391
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 248 bits (608), Expect = 2e-65
Identities = 118/296 (39%), Positives = 189/296 (63%), Gaps = 6/296 (2%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DF +K IG G++G+V L R K ++A+KV++K ++++ KH++ E+ +L + ++
Sbjct: 97 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L YI GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+V+RD+KPENIL+DS G++ L DFG CK T T CGTPEYLAPEV+ + Y
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDR 276
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ + ++Y+ +L + N++ ++LL+GLLQ D
Sbjct: 277 TVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDR 336
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQ 312
+KR+G+ K EIKSH +F+ ++W + ++K+ PF P S P + +F PE +
Sbjct: 337 TKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNELRHFDPEFTE 391
>BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 248 bits (607), Expect = 2e-65
Identities = 117/301 (38%), Positives = 188/301 (62%), Gaps = 6/301 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G YG+V L + K ++A+KV++K ++++ H++ E+ +L + ++
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L Y+ GGE+F ++Q+ F + +FYA++V A++YLH
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIDYLHSL 153
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+KPENIL+D G++ L DFG CK + T T CGTPEYLAPEV+ + Y
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ D +++YE +L + P + +LL+ LL D
Sbjct: 214 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 273
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPKLR 316
+R+GS K EIK+H +F+ ++W ++H++L PF P + P D +F PE Q +
Sbjct: 274 RQRLGS-KADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVS 332
Query: 317 K 317
K
Sbjct: 333 K 333
>Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 246 bits (603), Expect = 6e-65
Identities = 117/301 (38%), Positives = 187/301 (62%), Gaps = 6/301 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G YG+V L + K ++A+KV++K ++++ H++ E+ +L + ++
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L Y+ GGE+F ++Q+ F + +FYA++V A+ YLH
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+KPENIL+D G++ L DFG CK + T T CGTPEYLAPEV+ + Y
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ D +++YE +L + P + +LL+ LL D
Sbjct: 214 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 273
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPKLR 316
+R+GS K EIK+H +F+ ++W ++H++L PF P + P D +F PE Q +
Sbjct: 274 RQRLGS-KADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVS 332
Query: 317 K 317
K
Sbjct: 333 K 333
>Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 427
Score = 246 bits (603), Expect = 6e-65
Identities = 117/301 (38%), Positives = 187/301 (62%), Gaps = 6/301 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G YG+V L + K ++A+KV++K ++++ H++ E+ +L + ++
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L Y+ GGE+F ++Q+ F + +FYA++V A+ YLH
Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+KPENIL+D G++ L DFG CK + T T CGTPEYLAPEV+ + Y
Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 273
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ D +++YE +L + P + +LL+ LL D
Sbjct: 274 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 333
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPKLR 316
+R+GS K EIK+H +F+ ++W ++H++L PF P + P D +F PE Q +
Sbjct: 334 RQRLGS-KADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVS 392
Query: 317 K 317
K
Sbjct: 393 K 393
>BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein.
Length = 367
Score = 246 bits (603), Expect = 6e-65
Identities = 117/301 (38%), Positives = 187/301 (62%), Gaps = 6/301 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G YG+V L + K ++A+KV++K ++++ H++ E+ +L + ++
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L Y+ GGE+F ++Q+ F + +FYA++V A+ YLH
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+KPENIL+D G++ L DFG CK + T T CGTPEYLAPEV+ + Y
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ D +++YE +L + P + +LL+ LL D
Sbjct: 214 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 273
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPKLR 316
+R+GS K EIK+H +F+ ++W ++H++L PF P + P D +F PE Q +
Sbjct: 274 RQRLGS-KADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVS 332
Query: 317 K 317
K
Sbjct: 333 K 333
>BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 246 bits (603), Expect = 6e-65
Identities = 117/301 (38%), Positives = 187/301 (62%), Gaps = 6/301 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G YG+V L + K ++A+KV++K ++++ H++ E+ +L + ++
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L Y+ GGE+F ++Q+ F + +FYA++V A+ YLH
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+KPENIL+D G++ L DFG CK + T T CGTPEYLAPEV+ + Y
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ D +++YE +L + P + +LL+ LL D
Sbjct: 214 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 273
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPKLR 316
+R+GS K EIK+H +F+ ++W ++H++L PF P + P D +F PE Q +
Sbjct: 274 RQRLGS-KADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVS 332
Query: 317 K 317
K
Sbjct: 333 K 333
>AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein.
Length = 427
Score = 246 bits (603), Expect = 6e-65
Identities = 117/301 (38%), Positives = 187/301 (62%), Gaps = 6/301 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G YG+V L + K ++A+KV++K ++++ H++ E+ +L + ++
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L Y+ GGE+F ++Q+ F + +FYA++V A+ YLH
Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+KPENIL+D G++ L DFG CK + T T CGTPEYLAPEV+ + Y
Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 273
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ D +++YE +L + P + +LL+ LL D
Sbjct: 274 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 333
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPKLR 316
+R+GS K EIK+H +F+ ++W ++H++L PF P + P D +F PE Q +
Sbjct: 334 RQRLGS-KADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVS 392
Query: 317 K 317
K
Sbjct: 393 K 393
>AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein.
Length = 367
Score = 246 bits (603), Expect = 6e-65
Identities = 117/301 (38%), Positives = 187/301 (62%), Gaps = 6/301 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G YG+V L + K ++A+KV++K ++++ H++ E+ +L + ++
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 93
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L Y+ GGE+F ++Q+ F + +FYA++V A+ YLH
Sbjct: 94 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 153
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+KPENIL+D G++ L DFG CK + T T CGTPEYLAPEV+ + Y
Sbjct: 154 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 213
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ D +++YE +L + P + +LL+ LL D
Sbjct: 214 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 273
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPKLR 316
+R+GS K EIK+H +F+ ++W ++H++L PF P + P D +F PE Q +
Sbjct: 274 RQRLGS-KADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVS 332
Query: 317 K 317
K
Sbjct: 333 K 333
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 245 bits (600), Expect = 1e-64
Identities = 118/297 (39%), Positives = 182/297 (61%), Gaps = 4/297 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81
+ +I+ +G G +G V LV+ K AMK + K +V+ +H+ EK+IL+ + P
Sbjct: 452 NLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSP 511
Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141
F+V L FKDN Y+Y +L GGE+++ ++ G F + +KF + V A +YLH
Sbjct: 512 FIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLG 571
Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYSFSV 199
+++RD+KPEN+++D+ GYLKL DFGF K + +KTWT CGTPEY+APEVI +KG+ FSV
Sbjct: 572 IIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSV 631
Query: 200 DWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC--PENMSPECKNLLKGLLQVDP 257
D+W+LG L +E+ G+PPF D Y +L G K P ++ ++L++ L + +P
Sbjct: 632 DFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNP 691
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPK 314
++R+G+LK GI +IK H W NG +W+ + + L +P P D S F + P K
Sbjct: 692 TERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEK 748
>AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 393
Score = 244 bits (598), Expect = 3e-64
Identities = 117/301 (38%), Positives = 186/301 (61%), Gaps = 6/301 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G YG+V L + K ++A+KV++K ++++ H++ E+ +L + ++
Sbjct: 60 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 119
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L Y+ GGE+F ++Q+ F + +FYA++V A+ YLH
Sbjct: 120 PFLVGLRYSFQTPEELYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 179
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+KPENIL+D G++ L DFG CK + T T CGTPEYLAPEV+ + Y
Sbjct: 180 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 239
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ D +++YE +L + P + +LL+ LL D
Sbjct: 240 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 299
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPKLR 316
+R GS K EIK+H +F+ ++W ++H++L PF P + P D +F PE Q +
Sbjct: 300 RQRPGS-KADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVS 358
Query: 317 K 317
K
Sbjct: 359 K 359
>Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 366
Score = 243 bits (594), Expect = 8e-64
Identities = 117/301 (38%), Positives = 188/301 (62%), Gaps = 7/301 (2%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G YG+V L + K ++A+KV++K ++++ + H++ E+ +L + ++
Sbjct: 34 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKES-HIMAERSVLLKNVRH 92
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L Y+ GGE+F ++Q+ F + +FYA++V A+ YLH
Sbjct: 93 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 152
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+KPENIL+D G++ L DFG CK + T T CGTPEYLAPEV+ + Y
Sbjct: 153 NIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDR 212
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF++ D +++YE +L + P + +LL+ LL D
Sbjct: 213 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQ 272
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PEIPQPKLR 316
+R+GS K EIK+H +F+ ++W ++H++L PF P + P D +F PE Q +
Sbjct: 273 RQRLGS-KADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVS 331
Query: 317 K 317
K
Sbjct: 332 K 332
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 243 bits (594), Expect = 8e-64
Identities = 117/297 (39%), Positives = 181/297 (60%), Gaps = 4/297 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81
+ +I+ + G +G V LV+ K AMK + K +V+ +H+ EK+IL+ + P
Sbjct: 452 NLEIIATLAVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSP 511
Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141
F+V L FKDN Y+Y +L GGE+++ ++ G F + +KF + V A +YLH
Sbjct: 512 FIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLG 571
Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYSFSV 199
+++RD+KPEN+++D+ GYLKL DFGF K + +KTWT CGTPEY+APEVI +KG+ FSV
Sbjct: 572 IIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSV 631
Query: 200 DWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC--PENMSPECKNLLKGLLQVDP 257
D+W+LG L +E+ G+PPF D Y +L G K P ++ ++L++ L + +P
Sbjct: 632 DFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNP 691
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPEIPQPK 314
++R+G+LK GI +IK H W NG +W+ + + L +P P D S F + P K
Sbjct: 692 TERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEK 748
>CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein.
Length = 429
Score = 241 bits (590), Expect = 2e-63
Identities = 114/290 (39%), Positives = 180/290 (62%), Gaps = 5/290 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G++G+V L + K+ ++A+KV++K +V+ R KH++ E+ +L + ++
Sbjct: 94 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 153
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L ++ GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 154 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 213
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
++V+RD+KPENIL+DS G++ L DFG CK + T T CGTPEYLAPEVI + Y
Sbjct: 214 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 273
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF+ D ++Y+ +L +S ++L+ LL+ D
Sbjct: 274 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDR 333
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
R+G+ K EI++H +F L W + +K+ PF P + P D NF
Sbjct: 334 QNRLGA-KEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNF 382
>BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase family, member 3 protein.
Length = 496
Score = 241 bits (590), Expect = 2e-63
Identities = 114/290 (39%), Positives = 180/290 (62%), Gaps = 5/290 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G++G+V L + K+ ++A+KV++K +V+ R KH++ E+ +L + ++
Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L ++ GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
++V+RD+KPENIL+DS G++ L DFG CK + T T CGTPEYLAPEVI + Y
Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 340
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF+ D ++Y+ +L +S ++L+ LL+ D
Sbjct: 341 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDR 400
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
R+G+ K EI++H +F L W + +K+ PF P + P D NF
Sbjct: 401 QNRLGA-KEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNF 449
>AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase-like isoform 1 variant protein.
Length = 496
Score = 241 bits (590), Expect = 2e-63
Identities = 114/290 (39%), Positives = 180/290 (62%), Gaps = 5/290 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G++G+V L + K+ ++A+KV++K +V+ R KH++ E+ +L + ++
Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L ++ GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
++V+RD+KPENIL+DS G++ L DFG CK + T T CGTPEYLAPEVI + Y
Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 340
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF+ D ++Y+ +L +S ++L+ LL+ D
Sbjct: 341 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDR 400
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
R+G+ K EI++H +F L W + +K+ PF P + P D NF
Sbjct: 401 QNRLGA-KEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNF 449
>AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein.
Length = 429
Score = 241 bits (590), Expect = 2e-63
Identities = 114/290 (39%), Positives = 180/290 (62%), Gaps = 5/290 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G++G+V L + K+ ++A+KV++K +V+ R KH++ E+ +L + ++
Sbjct: 94 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 153
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L ++ GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 154 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 213
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
++V+RD+KPENIL+DS G++ L DFG CK + T T CGTPEYLAPEVI + Y
Sbjct: 214 KIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 273
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF+ D ++Y+ +L +S ++L+ LL+ D
Sbjct: 274 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDR 333
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
R+G+ K EI++H +F L W + +K+ PF P + P D NF
Sbjct: 334 QNRLGA-KEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNF 382
>AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL
protein.
Length = 496
Score = 240 bits (588), Expect = 4e-63
Identities = 114/290 (39%), Positives = 179/290 (61%), Gaps = 5/290 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCIQF 80
DFD +K IG G++G+V L + K+ +A+KV++K +V+ R KH++ E+ +L + ++
Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+V L +F+ LYF+L ++ GGE+F ++Q+ F + +FYA+++ AL YLH
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGYSF 197
++V+RD+KPENIL+DS G++ L DFG CK + T T CGTPEYLAPEVI + Y
Sbjct: 281 KIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDN 340
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
+VDWW LG + +EM G PPF+ D ++Y+ +L +S ++L+ LL+ D
Sbjct: 341 TVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLRAWSILEELLEKDR 400
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
R+G+ K EI++H +F L W + +K+ PF P + P D NF
Sbjct: 401 QNRLGA-KEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNF 449
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 239 bits (584), Expect = 1e-62
Identities = 112/276 (40%), Positives = 175/276 (63%), Gaps = 4/276 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81
+ +I+ +G G +G V LV+ K AMK + K +V+ +H+ EK+IL+ + P
Sbjct: 452 NLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSP 511
Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141
F+V L FKDN Y+Y +L GGE+++ ++ G F + +KF + V A +YLH
Sbjct: 512 FIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLG 571
Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKVL--KKKTWTLCGTPEYLAPEVITSKGYSFSV 199
+++RD+KPEN+++D+ GYLKL DFGF K + +KTWT CGTPEY+APEVI +KG+ FSV
Sbjct: 572 IIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSV 631
Query: 200 DWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC--PENMSPECKNLLKGLLQVDP 257
D+W+LG L +E+ G+PPF D Y +L G K P ++ ++L++ L + +P
Sbjct: 632 DFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNP 691
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAP 293
++R+G+LK GI +IK H W NG +W+ + + L +P
Sbjct: 692 TERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSP 727
>Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 232 bits (568), Expect = 1e-60
Identities = 104/230 (45%), Positives = 155/230 (67%), Gaps = 2/230 (0%)
Query: 12 DAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILE 71
+AP Y + D D + +G G +G V LV++K + A+KV+ V+ R +H+ E
Sbjct: 40 EAPAY--RLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNE 97
Query: 72 KKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVI 131
K +L+ + PF++ L + + +LY ++ Y+ GGE+F+Y++ G FS + FY++++I
Sbjct: 98 KSVLKEVSHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEII 157
Query: 132 LALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVIT 191
A+EYLH E+V+RD+KPENIL+D +G++KL DFGF K L +TWTLCGTPEYLAPEVI
Sbjct: 158 CAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQ 217
Query: 192 SKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENM 241
SKG+ +VDWWALG L FEM +G PPFF +P +Y+K+L G P ++
Sbjct: 218 SKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHL 267
>Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 232 bits (568), Expect = 1e-60
Identities = 104/230 (45%), Positives = 155/230 (67%), Gaps = 2/230 (0%)
Query: 12 DAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILE 71
+AP Y + D D + +G G +G V LV++K + A+KV+ V+ R +H+ E
Sbjct: 40 EAPAY--RLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNE 97
Query: 72 KKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVI 131
K +L+ + PF++ L + + +LY ++ Y+ GGE+F+Y++ G FS + FY++++I
Sbjct: 98 KSVLKEVSHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEII 157
Query: 132 LALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVIT 191
A+EYLH E+V+RD+KPENIL+D +G++KL DFGF K L +TWTLCGTPEYLAPEVI
Sbjct: 158 CAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQ 217
Query: 192 SKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENM 241
SKG+ +VDWWALG L FEM +G PPFF +P +Y+K+L G P ++
Sbjct: 218 SKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHL 267
>BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 232 bits (568), Expect = 1e-60
Identities = 104/230 (45%), Positives = 155/230 (67%), Gaps = 2/230 (0%)
Query: 12 DAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILE 71
+AP Y + D D + +G G +G V LV++K + A+KV+ V+ R +H+ E
Sbjct: 40 EAPAY--RLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNE 97
Query: 72 KKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVI 131
K +L+ + PF++ L + + +LY ++ Y+ GGE+F+Y++ G FS + FY++++I
Sbjct: 98 KSVLKEVSHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEII 157
Query: 132 LALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVIT 191
A+EYLH E+V+RD+KPENIL+D +G++KL DFGF K L +TWTLCGTPEYLAPEVI
Sbjct: 158 CAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQ 217
Query: 192 SKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENM 241
SKG+ +VDWWALG L FEM +G PPFF +P +Y+K+L G P ++
Sbjct: 218 SKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHL 267
>BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 232 bits (568), Expect = 1e-60
Identities = 104/230 (45%), Positives = 155/230 (67%), Gaps = 2/230 (0%)
Query: 12 DAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILE 71
+AP Y + D D + +G G +G V LV++K + A+KV+ V+ R +H+ E
Sbjct: 40 EAPAY--RLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNE 97
Query: 72 KKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVI 131
K +L+ + PF++ L + + +LY ++ Y+ GGE+F+Y++ G FS + FY++++I
Sbjct: 98 KSVLKEVSHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEII 157
Query: 132 LALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTPEYLAPEVIT 191
A+EYLH E+V+RD+KPENIL+D +G++KL DFGF K L +TWTLCGTPEYLAPEVI
Sbjct: 158 CAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQ 217
Query: 192 SKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENM 241
SKG+ +VDWWALG L FEM +G PPFF +P +Y+K+L G P ++
Sbjct: 218 SKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHL 267
>BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein.
Length = 524
Score = 232 bits (568), Expect = 1e-60
Identities = 122/305 (40%), Positives = 188/305 (61%), Gaps = 14/305 (4%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDK---ITFTYHAMKVVEKSVVVERNHAK-HLILEKKI 74
+V++F+++K +G GAYG+VFLVR +AMKV+ K+ +V+R + H E+ +
Sbjct: 29 SVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSV 88
Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
L+ + Q PF+VTL AF+ + L+ IL Y++GGEMFT++ + F ++ + Y +++LA
Sbjct: 89 LELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLA 148
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEV 189
LE+LH +++RD+K EN+L+DS G++ L DFG K K++T++ CGT EY+APE+
Sbjct: 149 LEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEI 208
Query: 190 ITSK-GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC----PENMSPE 244
I SK G+ +VDWW+LG L FE+ G PF +V KC P + P
Sbjct: 209 IRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPV 268
Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304
++LL+ LL DP KR+G+ G E+++H +F GLDW A+ +K+ APF P S D
Sbjct: 269 AQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDV 328
Query: 305 SNFPE 309
NF E
Sbjct: 329 GNFAE 333
Score = 30.7 bits (66), Expect = 7.4
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 239 ENMSPECKNLLKGLLQVDPSKRI 261
+ +S E K L++GLL VDP+KR+
Sbjct: 393 QGVSEEAKELVRGLLTVDPAKRL 415
>BC028079-1|AAH28079.1| 556|Homo sapiens Unknown (protein for
IMAGE:5216639) protein.
Length = 556
Score = 232 bits (568), Expect = 1e-60
Identities = 122/305 (40%), Positives = 188/305 (61%), Gaps = 14/305 (4%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDK---ITFTYHAMKVVEKSVVVERNHAK-HLILEKKI 74
+V++F+++K +G GAYG+VFLVR +AMKV+ K+ +V+R + H E+ +
Sbjct: 29 SVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSV 88
Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
L+ + Q PF+VTL AF+ + L+ IL Y++GGEMFT++ + F ++ + Y +++LA
Sbjct: 89 LELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLA 148
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEV 189
LE+LH +++RD+K EN+L+DS G++ L DFG K K++T++ CGT EY+APE+
Sbjct: 149 LEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEI 208
Query: 190 ITSK-GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC----PENMSPE 244
I SK G+ +VDWW+LG L FE+ G PF +V KC P + P
Sbjct: 209 IRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPV 268
Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304
++LL+ LL DP KR+G+ G E+++H +F GLDW A+ +K+ APF P S D
Sbjct: 269 AQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDV 328
Query: 305 SNFPE 309
NF E
Sbjct: 329 GNFAE 333
Score = 67.3 bits (157), Expect = 7e-11
Identities = 45/146 (30%), Positives = 75/146 (51%), Gaps = 9/146 (6%)
Query: 28 AIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLD 87
A+G G++ R + + A+K++ + + E N + + + C P VV L
Sbjct: 416 ALGQGSFSVCRRCRQRQSGQEFAVKILSRRL--EANTQREVAA---LRLCQSHPNVVNLH 470
Query: 88 VAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH-YCEVVHRD 146
D L+ Y +L + GGE+ +I+K FS+S ++ A+ ++H VVHRD
Sbjct: 471 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 530
Query: 147 IKPENILI--DSNGY-LKLCDFGFCK 169
+KPENIL D+ G +K+ DFGF +
Sbjct: 531 LKPENILYADDTPGAPVKIIDFGFAR 556
>AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 4 isoform b variant protein.
Length = 765
Score = 232 bits (568), Expect = 1e-60
Identities = 122/305 (40%), Positives = 188/305 (61%), Gaps = 14/305 (4%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDK---ITFTYHAMKVVEKSVVVERNHAK-HLILEKKI 74
+V++F+++K +G GAYG+VFLVR +AMKV+ K+ +V+R + H E+ +
Sbjct: 29 SVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSV 88
Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
L+ + Q PF+VTL AF+ + L+ IL Y++GGEMFT++ + F ++ + Y +++LA
Sbjct: 89 LELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLA 148
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEV 189
LE+LH +++RD+K EN+L+DS G++ L DFG K K++T++ CGT EY+APE+
Sbjct: 149 LEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEI 208
Query: 190 ITSK-GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC----PENMSPE 244
I SK G+ +VDWW+LG L FE+ G PF +V KC P + P
Sbjct: 209 IRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPV 268
Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304
++LL+ LL DP KR+G+ G E+++H +F GLDW A+ +K+ APF P S D
Sbjct: 269 AQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDV 328
Query: 305 SNFPE 309
NF E
Sbjct: 329 GNFAE 333
Score = 107 bits (256), Expect = 7e-23
Identities = 77/253 (30%), Positives = 127/253 (50%), Gaps = 24/253 (9%)
Query: 28 AIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLD 87
A+G G++ R + + A+K++ + + E N + + + C P VV L
Sbjct: 409 ALGQGSFSVCRRCRQRQSGQEFAVKILSRRL--EANTQREVAA---LRLCQSHPNVVNLH 463
Query: 88 VAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY-CEVVHRD 146
D + Y +L + GGE+ +I+K FS+S ++ A+ ++H VVHRD
Sbjct: 464 EVHHDQPHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 523
Query: 147 IKPENILI--DSNGY-LKLCDFGFCKVLKKKTW----TLCGTPEYLAPEVITSKGYSFSV 199
+KPENIL D+ G +K+ DFGF ++ + T C T +Y APE++ +GY S
Sbjct: 524 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESC 583
Query: 200 DWWALGDLSFEMEAGHPPFFA-------SDPNKLYEKVLVGSYKCP----ENMSPECKNL 248
D W+LG + + M +G PF S ++ K+ G + + +S E K L
Sbjct: 584 DLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKEL 643
Query: 249 LKGLLQVDPSKRI 261
++GLL VDP+KR+
Sbjct: 644 VRGLLTVDPAKRL 656
>AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinase B
(RSK-B) protein.
Length = 772
Score = 232 bits (568), Expect = 1e-60
Identities = 122/305 (40%), Positives = 188/305 (61%), Gaps = 14/305 (4%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDK---ITFTYHAMKVVEKSVVVERNHAK-HLILEKKI 74
+V++F+++K +G GAYG+VFLVR +AMKV+ K+ +V+R + H E+ +
Sbjct: 29 SVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSV 88
Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
L+ + Q PF+VTL AF+ + L+ IL Y++GGEMFT++ + F ++ + Y +++LA
Sbjct: 89 LELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLA 148
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEV 189
LE+LH +++RD+K EN+L+DS G++ L DFG K K++T++ CGT EY+APE+
Sbjct: 149 LEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEI 208
Query: 190 ITSK-GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC----PENMSPE 244
I SK G+ +VDWW+LG L FE+ G PF +V KC P + P
Sbjct: 209 IRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPV 268
Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304
++LL+ LL DP KR+G+ G E+++H +F GLDW A+ +K+ APF P S D
Sbjct: 269 AQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDV 328
Query: 305 SNFPE 309
NF E
Sbjct: 329 GNFAE 333
Score = 109 bits (263), Expect = 1e-23
Identities = 78/253 (30%), Positives = 128/253 (50%), Gaps = 24/253 (9%)
Query: 28 AIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLD 87
A+G G++ R + + A+K++ + + E N + + + C P VV L
Sbjct: 416 ALGQGSFSVCRRCRQRQSGQEFAVKILSRRL--EANTQREVAA---LRLCQSHPNVVNLH 470
Query: 88 VAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY-CEVVHRD 146
D L+ Y +L + GGE+ +I+K FS+S ++ A+ ++H VVHRD
Sbjct: 471 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 530
Query: 147 IKPENILI--DSNGY-LKLCDFGFCKVLKKKTW----TLCGTPEYLAPEVITSKGYSFSV 199
+KPENIL D+ G +K+ DFGF ++ + T C T +Y APE++ +GY S
Sbjct: 531 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESC 590
Query: 200 DWWALGDLSFEMEAGHPPFFA-------SDPNKLYEKVLVGSYKCP----ENMSPECKNL 248
D W+LG + + M +G PF S ++ K+ G + + +S E K L
Sbjct: 591 DLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKEL 650
Query: 249 LKGLLQVDPSKRI 261
++GLL VDP+KR+
Sbjct: 651 VRGLLTVDPAKRL 663
>AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and
stress-activated protein kinase-2 protein.
Length = 705
Score = 232 bits (568), Expect = 1e-60
Identities = 122/305 (40%), Positives = 188/305 (61%), Gaps = 14/305 (4%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDK---ITFTYHAMKVVEKSVVVERNHAK-HLILEKKI 74
+V++F+++K +G GAYG+VFLVR +AMKV+ K+ +V+R + H E+ +
Sbjct: 13 SVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSV 72
Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
L+ + Q PF+VTL AF+ + L+ IL Y++GGEMFT++ + F ++ + Y +++LA
Sbjct: 73 LELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLA 132
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEV 189
LE+LH +++RD+K EN+L+DS G++ L DFG K K++T++ CGT EY+APE+
Sbjct: 133 LEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEI 192
Query: 190 ITSK-GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKC----PENMSPE 244
I SK G+ +VDWW+LG L FE+ G PF +V KC P + P
Sbjct: 193 IRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPV 252
Query: 245 CKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDT 304
++LL+ LL DP KR+G+ G E+++H +F GLDW A+ +K+ APF P S D
Sbjct: 253 AQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDV 312
Query: 305 SNFPE 309
NF E
Sbjct: 313 GNFAE 317
Score = 109 bits (263), Expect = 1e-23
Identities = 78/253 (30%), Positives = 128/253 (50%), Gaps = 24/253 (9%)
Query: 28 AIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPFVVTLD 87
A+G G++ R + + A+K++ + + E N + + + C P VV L
Sbjct: 394 ALGQGSFSVCRRCRQRQSGQEFAVKILSRRL--EANTQREVAA---LRLCQSHPNVVNLH 448
Query: 88 VAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY-CEVVHRD 146
D L+ Y +L + GGE+ +I+K FS+S ++ A+ ++H VVHRD
Sbjct: 449 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 508
Query: 147 IKPENILI--DSNGY-LKLCDFGFCKVLKKKTW----TLCGTPEYLAPEVITSKGYSFSV 199
+KPENIL D+ G +K+ DFGF ++ + T C T +Y APE++ +GY S
Sbjct: 509 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESC 568
Query: 200 DWWALGDLSFEMEAGHPPFFA-------SDPNKLYEKVLVGSYKCP----ENMSPECKNL 248
D W+LG + + M +G PF S ++ K+ G + + +S E K L
Sbjct: 569 DLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKEL 628
Query: 249 LKGLLQVDPSKRI 261
++GLL VDP+KR+
Sbjct: 629 VRGLLTVDPAKRL 641
>L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kinase
1 protein.
Length = 735
Score = 229 bits (560), Expect = 1e-59
Identities = 112/292 (38%), Positives = 180/292 (61%), Gaps = 9/292 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
F+++K +G G++G+VFLVR K+T +AMKV++K+ + R+ + +E+ IL +
Sbjct: 62 FELLKVLGQGSFGKVFLVR-KVTRPDSGHLYAMKVLKKATLKVRDRVRTK-MERDILADV 119
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PFVV L AF+ LY IL ++ GG++FT + K +F++ KFY +++ L L++LH
Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+
Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH 239
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
S S DWW+ G L FEM G PF D + +L P+ +S E ++LL+ L +
Sbjct: 240 SHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKR 299
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+P+ R+GS G EIK H +++ +DW ++ +++ PF P + P DT F
Sbjct: 300 NPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREITPPFKPAVAQPDDTFYF 351
Score = 130 bits (315), Expect = 5e-30
Identities = 86/256 (33%), Positives = 139/256 (54%), Gaps = 22/256 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D + + + IG G+Y E K T +A+KV++KS +R+ ++ + + +L+ Q
Sbjct: 416 DGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKS---KRDPSEEIEI---LLRYGQH 469
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D ++Y + + GGE+ I + FS+ F + +EYLH
Sbjct: 470 PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQ 529
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL +D +G L++CDFGF K L+ + T C T ++APEV+ +
Sbjct: 530 GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 589
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY D W+LG L + M AG+ P FA+ P+ E++L +GS K +S
Sbjct: 590 GYDEGCDIWSLGILLYTMLAGYTP-FANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETA 648
Query: 246 KNLLKGLLQVDPSKRI 261
K+L+ +L VDP +R+
Sbjct: 649 KDLVSKMLHVDPHQRL 664
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 229 bits (559), Expect = 1e-59
Identities = 113/295 (38%), Positives = 186/295 (63%), Gaps = 10/295 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
F+++K +G G++G+VFLV+ KI+ + +AMKV++K+ + R+ + +E+ IL +
Sbjct: 68 FELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDRVRTK-MERDILVEV 125
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ S DWW+ G L FEM G PF D + +L P+ +SPE ++LL+ L +
Sbjct: 246 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKR 305
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
+P+ R+G+ G+ EIK H++F+ +DW ++ +++ PF P P DT F PE
Sbjct: 306 NPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 360
Score = 125 bits (301), Expect = 2e-28
Identities = 82/256 (32%), Positives = 137/256 (53%), Gaps = 22/256 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D +++ + IG G+Y K T A+K+++KS +R+ + + + +L+ Q
Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI---LLRYGQH 473
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D Y+Y + + GGE+ I + FS+ + +EYLH
Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 533
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL +D +G +++CDFGF K L+ + T C T ++APEV+ +
Sbjct: 534 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 593
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M G+ P FA+ P+ E++L +GS K ++S
Sbjct: 594 GYDAACDIWSLGVLLYTMLTGYTP-FANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 652
Query: 246 KNLLKGLLQVDPSKRI 261
K+L+ +L VDP +R+
Sbjct: 653 KDLVSKMLHVDPHQRL 668
>L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kinase
3 protein.
Length = 580
Score = 229 bits (559), Expect = 1e-59
Identities = 113/295 (38%), Positives = 186/295 (63%), Gaps = 10/295 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
F+++K +G G++G+VFLV+ KI+ + +AMKV++K+ + R+ + +E+ IL +
Sbjct: 67 FELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDRVRTK-MERDILVEV 124
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 125 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 184
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+
Sbjct: 185 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 244
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ S DWW+ G L FEM G PF D + +L P+ +SPE ++LL+ L +
Sbjct: 245 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKR 304
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
+P+ R+G+ G+ EIK H++F+ +DW ++ +++ PF P P DT F PE
Sbjct: 305 NPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 359
Score = 81.0 bits (191), Expect = 5e-15
Identities = 54/170 (31%), Positives = 91/170 (53%), Gaps = 12/170 (7%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D +++ + IG G+Y K T A+K+++KS +R+ + + + +L+ Q
Sbjct: 419 DGYELKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI---LLRYGQH 472
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL+ + D Y+Y ++ + GGE+ I + FS+ + +EYLH
Sbjct: 473 PNIITLNDVYDDGKYVY-VVTLMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 531
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKTWTLCGTPEYLA 186
VVHRD+KP NIL +D +G +++CDFGF K L+ + L TP Y A
Sbjct: 532 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLM-TPCYTA 580
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 229 bits (559), Expect = 1e-59
Identities = 113/295 (38%), Positives = 186/295 (63%), Gaps = 10/295 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
F+++K +G G++G+VFLV+ KI+ + +AMKV++K+ + R+ + +E+ IL +
Sbjct: 68 FELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDRVRTK-MERDILVEV 125
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ S DWW+ G L FEM G PF D + +L P+ +SPE ++LL+ L +
Sbjct: 246 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKR 305
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
+P+ R+G+ G+ EIK H++F+ +DW ++ +++ PF P P DT F PE
Sbjct: 306 NPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 360
Score = 125 bits (301), Expect = 2e-28
Identities = 82/256 (32%), Positives = 137/256 (53%), Gaps = 22/256 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D +++ + IG G+Y K T A+K+++KS +R+ + + + +L+ Q
Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI---LLRYGQH 473
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D Y+Y + + GGE+ I + FS+ + +EYLH
Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 533
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL +D +G +++CDFGF K L+ + T C T ++APEV+ +
Sbjct: 534 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 593
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M G+ P FA+ P+ E++L +GS K ++S
Sbjct: 594 GYDAACDIWSLGVLLYTMLTGYTP-FANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 652
Query: 246 KNLLKGLLQVDPSKRI 261
K+L+ +L VDP +R+
Sbjct: 653 KDLVSKMLHVDPHQRL 668
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 229 bits (559), Expect = 1e-59
Identities = 113/295 (38%), Positives = 186/295 (63%), Gaps = 10/295 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
F+++K +G G++G+VFLV+ KI+ + +AMKV++K+ + R+ + +E+ IL +
Sbjct: 68 FELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDRVRTK-MERDILVEV 125
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ S DWW+ G L FEM G PF D + +L P+ +SPE ++LL+ L +
Sbjct: 246 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKR 305
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
+P+ R+G+ G+ EIK H++F+ +DW ++ +++ PF P P DT F PE
Sbjct: 306 NPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 360
Score = 125 bits (301), Expect = 2e-28
Identities = 82/256 (32%), Positives = 137/256 (53%), Gaps = 22/256 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D +++ + IG G+Y K T A+K+++KS +R+ + + + +L+ Q
Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI---LLRYGQH 473
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D Y+Y + + GGE+ I + FS+ + +EYLH
Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 533
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL +D +G +++CDFGF K L+ + T C T ++APEV+ +
Sbjct: 534 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 593
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M G+ P FA+ P+ E++L +GS K ++S
Sbjct: 594 GYDAACDIWSLGVLLYTMLTGYTP-FANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 652
Query: 246 KNLLKGLLQVDPSKRI 261
K+L+ +L VDP +R+
Sbjct: 653 KDLVSKMLHVDPHQRL 668
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 229 bits (559), Expect = 1e-59
Identities = 113/295 (38%), Positives = 186/295 (63%), Gaps = 10/295 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
F+++K +G G++G+VFLV+ KI+ + +AMKV++K+ + R+ + +E+ IL +
Sbjct: 68 FELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDRVRTK-MERDILVEV 125
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ S DWW+ G L FEM G PF D + +L P+ +SPE ++LL+ L +
Sbjct: 246 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKR 305
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
+P+ R+G+ G+ EIK H++F+ +DW ++ +++ PF P P DT F PE
Sbjct: 306 NPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 360
Score = 125 bits (301), Expect = 2e-28
Identities = 82/256 (32%), Positives = 137/256 (53%), Gaps = 22/256 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D +++ + IG G+Y K T A+K+++KS +R+ + + + +L+ Q
Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI---LLRYGQH 473
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D Y+Y + + GGE+ I + FS+ + +EYLH
Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 533
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL +D +G +++CDFGF K L+ + T C T ++APEV+ +
Sbjct: 534 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 593
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M G+ P FA+ P+ E++L +GS K ++S
Sbjct: 594 GYDAACDIWSLGVLLYTMLTGYTP-FANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 652
Query: 246 KNLLKGLLQVDPSKRI 261
K+L+ +L VDP +R+
Sbjct: 653 KDLVSKMLHVDPHQRL 668
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 229 bits (559), Expect = 1e-59
Identities = 113/295 (38%), Positives = 186/295 (63%), Gaps = 10/295 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
F+++K +G G++G+VFLV+ KI+ + +AMKV++K+ + R+ + +E+ IL +
Sbjct: 68 FELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDRVRTK-MERDILVEV 125
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 126 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 185
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+
Sbjct: 186 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 245
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ S DWW+ G L FEM G PF D + +L P+ +SPE ++LL+ L +
Sbjct: 246 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKR 305
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
+P+ R+G+ G+ EIK H++F+ +DW ++ +++ PF P P DT F PE
Sbjct: 306 NPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 360
Score = 125 bits (301), Expect = 2e-28
Identities = 82/256 (32%), Positives = 137/256 (53%), Gaps = 22/256 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D +++ + IG G+Y K T A+K+++KS +R+ + + + +L+ Q
Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI---LLRYGQH 473
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D Y+Y + + GGE+ I + FS+ + +EYLH
Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 533
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL +D +G +++CDFGF K L+ + T C T ++APEV+ +
Sbjct: 534 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 593
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M G+ P FA+ P+ E++L +GS K ++S
Sbjct: 594 GYDAACDIWSLGVLLYTMLTGYTP-FANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 652
Query: 246 KNLLKGLLQVDPSKRI 261
K+L+ +L VDP +R+
Sbjct: 653 KDLVSKMLHVDPHQRL 668
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 variant protein.
Length = 806
Score = 229 bits (559), Expect = 1e-59
Identities = 113/295 (38%), Positives = 186/295 (63%), Gaps = 10/295 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
F+++K +G G++G+VFLV+ KI+ + +AMKV++K+ + R+ + +E+ IL +
Sbjct: 135 FELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDRVRTK-MERDILVEV 192
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 193 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 252
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+
Sbjct: 253 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 312
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ S DWW+ G L FEM G PF D + +L P+ +SPE ++LL+ L +
Sbjct: 313 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKR 372
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
+P+ R+G+ G+ EIK H++F+ +DW ++ +++ PF P P DT F PE
Sbjct: 373 NPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 427
Score = 125 bits (301), Expect = 2e-28
Identities = 82/256 (32%), Positives = 137/256 (53%), Gaps = 22/256 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D +++ + IG G+Y K T A+K+++KS +R+ + + + +L+ Q
Sbjct: 486 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI---LLRYGQH 539
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D Y+Y + + GGE+ I + FS+ + +EYLH
Sbjct: 540 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 599
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL +D +G +++CDFGF K L+ + T C T ++APEV+ +
Sbjct: 600 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 659
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M G+ P FA+ P+ E++L +GS K ++S
Sbjct: 660 GYDAACDIWSLGVLLYTMLTGYTP-FANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 718
Query: 246 KNLLKGLLQVDPSKRI 261
K+L+ +L VDP +R+
Sbjct: 719 KDLVSKMLHVDPHQRL 734
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 229 bits (559), Expect = 1e-59
Identities = 113/295 (38%), Positives = 186/295 (63%), Gaps = 10/295 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
F+++K +G G++G+VFLV+ KI+ + +AMKV++K+ + R+ + +E+ IL +
Sbjct: 54 FELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDRVRTK-MERDILVEV 111
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 112 NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLH 171
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+
Sbjct: 172 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGH 231
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ S DWW+ G L FEM G PF D + +L P+ +SPE ++LL+ L +
Sbjct: 232 TQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKR 291
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
+P+ R+G+ G+ EIK H++F+ +DW ++ +++ PF P P DT F PE
Sbjct: 292 NPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 346
Score = 125 bits (301), Expect = 2e-28
Identities = 82/256 (32%), Positives = 137/256 (53%), Gaps = 22/256 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D +++ + IG G+Y K T A+K+++KS +R+ + + + +L+ Q
Sbjct: 406 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI---LLRYGQH 459
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D Y+Y + + GGE+ I + FS+ + +EYLH
Sbjct: 460 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 519
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL +D +G +++CDFGF K L+ + T C T ++APEV+ +
Sbjct: 520 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 579
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M G+ P FA+ P+ E++L +GS K ++S
Sbjct: 580 GYDAACDIWSLGVLLYTMLTGYTP-FANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 638
Query: 246 KNLLKGLLQVDPSKRI 261
K+L+ +L VDP +R+
Sbjct: 639 KDLVSKMLHVDPHQRL 654
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 228 bits (558), Expect = 2e-59
Identities = 111/294 (37%), Positives = 183/294 (62%), Gaps = 8/294 (2%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
F+++K +G G++G+VFLV+ + +AMKV++K+ + R+ + +E+ IL +
Sbjct: 68 FELLKVLGQGSFGKVFLVKKILGSDARQLYAMKVLKKATLKVRDRVRTK-MERDILVEVN 126
Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 127 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 186
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G++
Sbjct: 187 LGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHT 246
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256
S DWW+ G L FEM G PF D + +L P+ +SPE ++LL+ L + +
Sbjct: 247 QSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRN 306
Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
P+ R+G+ G+ EIK H++F+ +DW ++ +++ PF P P DT F PE
Sbjct: 307 PANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPE 360
Score = 125 bits (301), Expect = 2e-28
Identities = 82/256 (32%), Positives = 137/256 (53%), Gaps = 22/256 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D +++ + IG G+Y K T A+K+++KS +R+ + + + +L+ Q
Sbjct: 420 DGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI---LLRYGQH 473
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D Y+Y + + GGE+ I + FS+ + +EYLH
Sbjct: 474 PNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQ 533
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL +D +G +++CDFGF K L+ + T C T ++APEV+ +
Sbjct: 534 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 593
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M G+ P FA+ P+ E++L +GS K ++S
Sbjct: 594 GYDAACDIWSLGVLLYTMLTGYTP-FANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 652
Query: 246 KNLLKGLLQVDPSKRI 261
K+L+ +L VDP +R+
Sbjct: 653 KDLVSKMLHVDPHQRL 668
>BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 228 bits (558), Expect = 2e-59
Identities = 112/292 (38%), Positives = 180/292 (61%), Gaps = 9/292 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
F+++K +G G++G+VFLVR K+T +AMKV++K+ + R+ + +E+ IL +
Sbjct: 62 FELLKVLGQGSFGKVFLVR-KVTRPDSGHLYAMKVLKKATLKVRDRVRTK-MERDILADV 119
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PFVV L AF+ LY IL ++ GG++FT + K +F++ KFY +++ L L++LH
Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+
Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH 239
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
S S DWW+ G L FEM G PF D + +L P+ +S E ++LL+ L +
Sbjct: 240 SHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKR 299
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+P+ R+GS G EIK H +++ +DW ++ +++ PF P + P DT F
Sbjct: 300 NPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYF 351
Score = 130 bits (315), Expect = 5e-30
Identities = 86/256 (33%), Positives = 139/256 (54%), Gaps = 22/256 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D + + + IG G+Y E K T +A+KV++KS +R+ ++ + + +L+ Q
Sbjct: 416 DGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKS---KRDPSEEIEI---LLRYGQH 469
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D ++Y + + GGE+ I + FS+ F + +EYLH
Sbjct: 470 PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQ 529
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL +D +G L++CDFGF K L+ + T C T ++APEV+ +
Sbjct: 530 GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 589
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY D W+LG L + M AG+ P FA+ P+ E++L +GS K +S
Sbjct: 590 GYDEGCDIWSLGILLYTMLAGYTP-FANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETA 648
Query: 246 KNLLKGLLQVDPSKRI 261
K+L+ +L VDP +R+
Sbjct: 649 KDLVSKMLHVDPHQRL 664
>BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 228 bits (558), Expect = 2e-59
Identities = 110/293 (37%), Positives = 179/293 (61%), Gaps = 9/293 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVER-NHAKHLILEKKILQC 77
F++++ +G G YG+VF VR K+ T +AMKV+ K+ +V H E+ IL+
Sbjct: 67 FELLRVLGKGGYGKVFQVR-KVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILES 125
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
++ PF+V L AF+ LY IL ++GGE+FT++++ GIF + FY +++ LAL +L
Sbjct: 126 VKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHL 185
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKG 194
H +++RD+KPENI++ S G++KL DFG CK + T T CGT EY+APE++ G
Sbjct: 186 HSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSG 245
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
++ +VDWW+LG L ++M G PPF A + K +K++ G P ++P+ ++L+K L+
Sbjct: 246 HNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLK 305
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+PS+RIG G +++ H +F ++W + ++ PF P S D S F
Sbjct: 306 RNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQF 358
>BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 228 bits (558), Expect = 2e-59
Identities = 110/293 (37%), Positives = 179/293 (61%), Gaps = 9/293 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVER-NHAKHLILEKKILQC 77
F++++ +G G YG+VF VR K+ T +AMKV+ K+ +V H E+ IL+
Sbjct: 67 FELLRVLGKGGYGKVFQVR-KVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILES 125
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
++ PF+V L AF+ LY IL ++GGE+FT++++ GIF + FY +++ LAL +L
Sbjct: 126 VKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHL 185
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKG 194
H +++RD+KPENI++ S G++KL DFG CK + T T CGT EY+APE++ G
Sbjct: 186 HSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSG 245
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
++ +VDWW+LG L ++M G PPF A + K +K++ G P ++P+ ++L+K L+
Sbjct: 246 HNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLK 305
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+PS+RIG G +++ H +F ++W + ++ PF P S D S F
Sbjct: 306 RNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQF 358
>AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 228 bits (558), Expect = 2e-59
Identities = 112/292 (38%), Positives = 180/292 (61%), Gaps = 9/292 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
F+++K +G G++G+VFLVR K+T +AMKV++K+ + R+ + +E+ IL +
Sbjct: 62 FELLKVLGQGSFGKVFLVR-KVTRPDSGHLYAMKVLKKATLKVRDRVRTK-MERDILADV 119
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PFVV L AF+ LY IL ++ GG++FT + K +F++ KFY +++ L L++LH
Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+
Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGH 239
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
S S DWW+ G L FEM G PF D + +L P+ +S E ++LL+ L +
Sbjct: 240 SHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKR 299
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+P+ R+GS G EIK H +++ +DW ++ +++ PF P + P DT F
Sbjct: 300 NPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYF 351
Score = 130 bits (315), Expect = 5e-30
Identities = 86/256 (33%), Positives = 139/256 (54%), Gaps = 22/256 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D + + + IG G+Y E K T +A+KV++KS +R+ ++ + + +L+ Q
Sbjct: 416 DGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKS---KRDPSEEIEI---LLRYGQH 469
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D ++Y + + GGE+ I + FS+ F + +EYLH
Sbjct: 470 PNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQ 529
Query: 141 EVVHRDIKPENIL-IDSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL +D +G L++CDFGF K L+ + T C T ++APEV+ +
Sbjct: 530 GVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 589
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY D W+LG L + M AG+ P FA+ P+ E++L +GS K +S
Sbjct: 590 GYDEGCDIWSLGILLYTMLAGYTP-FANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETA 648
Query: 246 KNLLKGLLQVDPSKRI 261
K+L+ +L VDP +R+
Sbjct: 649 KDLVSKMLHVDPHQRL 664
>AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinase
protein.
Length = 482
Score = 228 bits (558), Expect = 2e-59
Identities = 110/293 (37%), Positives = 179/293 (61%), Gaps = 9/293 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVER-NHAKHLILEKKILQC 77
F++++ +G G YG+VF VR K+ T +AMKV+ K+ +V H E+ IL+
Sbjct: 67 FELLRVLGKGGYGKVFQVR-KVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILES 125
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
++ PF+V L AF+ LY IL ++GGE+FT++++ GIF + FY +++ LAL +L
Sbjct: 126 VKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHL 185
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKG 194
H +++RD+KPENI++ S G++KL DFG CK + T T CGT EY+APE++ G
Sbjct: 186 HSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSG 245
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
++ +VDWW+LG L ++M G PPF A + K +K++ G P ++P+ ++L+K L+
Sbjct: 246 HNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLK 305
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+PS+RIG G +++ H +F ++W + ++ PF P S D S F
Sbjct: 306 RNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQF 358
>AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase 14
beta protein.
Length = 482
Score = 228 bits (558), Expect = 2e-59
Identities = 110/293 (37%), Positives = 179/293 (61%), Gaps = 9/293 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVER-NHAKHLILEKKILQC 77
F++++ +G G YG+VF VR K+ T +AMKV+ K+ +V H E+ IL+
Sbjct: 67 FELLRVLGKGGYGKVFQVR-KVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILES 125
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
++ PF+V L AF+ LY IL ++GGE+FT++++ GIF + FY +++ LAL +L
Sbjct: 126 VKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHL 185
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKG 194
H +++RD+KPENI++ S G++KL DFG CK + T T CGT EY+APE++ G
Sbjct: 186 HSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSG 245
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
++ +VDWW+LG L ++M G PPF A + K +K++ G P ++P+ ++L+K L+
Sbjct: 246 HNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLK 305
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+PS+RIG G +++ H +F ++W + ++ PF P S D S F
Sbjct: 306 RNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQF 358
>AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase
beta protein.
Length = 495
Score = 228 bits (558), Expect = 2e-59
Identities = 110/293 (37%), Positives = 179/293 (61%), Gaps = 9/293 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFT----YHAMKVVEKSVVVER-NHAKHLILEKKILQC 77
F++++ +G G YG+VF VR K+ T +AMKV+ K+ +V H E+ IL+
Sbjct: 80 FELLRVLGKGGYGKVFQVR-KVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILES 138
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
++ PF+V L AF+ LY IL ++GGE+FT++++ GIF + FY +++ LAL +L
Sbjct: 139 VKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHL 198
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKG 194
H +++RD+KPENI++ S G++KL DFG CK + T T CGT EY+APE++ G
Sbjct: 199 HSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSG 258
Query: 195 YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQ 254
++ +VDWW+LG L ++M G PPF A + K +K++ G P ++P+ ++L+K L+
Sbjct: 259 HNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLK 318
Query: 255 VDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+PS+RIG G +++ H +F ++W + ++ PF P S D S F
Sbjct: 319 RNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQF 371
>AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein.
Length = 481
Score = 227 bits (555), Expect = 4e-59
Identities = 109/292 (37%), Positives = 178/292 (60%), Gaps = 8/292 (2%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTY---HAMKVVEKSVVVER-NHAKHLILEKKILQCI 78
F++++ +G G YG+VF VR K+ +AMKV+ K+ +V H E+ IL+ +
Sbjct: 67 FELLRVLGKGGYGKVFQVR-KVQGNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 125
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+V L AF+ LY IL ++GGE+FT++++ GIF + FY +++ LAL +LH
Sbjct: 126 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 185
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENI++ S G++KL DFG CK + T T CGT EY+APE++ G+
Sbjct: 186 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 245
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ +VDWW+LG L ++M G PPF A + K +K++ G P ++P+ ++L+K L+
Sbjct: 246 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 305
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+PS+RIG G +++ H +F ++W + ++ PF P S D S F
Sbjct: 306 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQF 357
>AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 227 bits (554), Expect = 6e-59
Identities = 116/294 (39%), Positives = 181/294 (61%), Gaps = 10/294 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
F+++K +G G++G+VFLVR K +AMKV++K+ + R+ + +E+ IL +
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTK-MERDILVEVN 131
Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGYS 196
+V+RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+S
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256
S DWW+ G L FEM G PF D N+ +L P+ +S E ++LL+ L + +
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRN 311
Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
P+ R+GS G+ EIK H +F +DW ++ +++ PF P P DT F PE
Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPE 363
Score = 122 bits (293), Expect = 2e-27
Identities = 86/274 (31%), Positives = 143/274 (52%), Gaps = 27/274 (9%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPF 82
+++ + IG G+Y T A+K+++KS +R+ ++ + + +++ Q P
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKS---KRDPSEEIEI---LMRYGQHPN 479
Query: 83 VVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEV 142
++TL F D Y+Y + + GGE+ I K FS+ + ++YLH V
Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539
Query: 143 VHRDIKPENIL-ID---SNGYLKLCDFGFCKVLKKKTWTL---CGTPEYLAPEVITSKGY 195
VHRD+KP NIL +D S +++CDFGF K L+ + L C T ++APEV+ +GY
Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGY 599
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPECKN 247
+ D W+LG L + M AG+ P FA+ PN E++L +G+ K +N+S K+
Sbjct: 600 DAACDIWSLGVLFYTMLAGYTP-FANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKD 658
Query: 248 LLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLD 281
LL +L +DP +R + +I H+W D
Sbjct: 659 LLSHMLHMDPHQRYTA-----EQILKHSWITHRD 687
>AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 227 bits (554), Expect = 6e-59
Identities = 116/294 (39%), Positives = 181/294 (61%), Gaps = 10/294 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
F+++K +G G++G+VFLVR K +AMKV++K+ + R+ + +E+ IL +
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTK-MERDILVEVN 131
Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGYS 196
+V+RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+S
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256
S DWW+ G L FEM G PF D N+ +L P+ +S E ++LL+ L + +
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRN 311
Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
P+ R+GS G+ EIK H +F +DW ++ +++ PF P P DT F PE
Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPE 363
Score = 122 bits (293), Expect = 2e-27
Identities = 86/274 (31%), Positives = 143/274 (52%), Gaps = 27/274 (9%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPF 82
+++ + IG G+Y T A+K+++KS +R+ ++ + + +++ Q P
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKS---KRDPSEEIEI---LMRYGQHPN 479
Query: 83 VVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEV 142
++TL F D Y+Y + + GGE+ I K FS+ + ++YLH V
Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539
Query: 143 VHRDIKPENIL-ID---SNGYLKLCDFGFCKVLKKKTWTL---CGTPEYLAPEVITSKGY 195
VHRD+KP NIL +D S +++CDFGF K L+ + L C T ++APEV+ +GY
Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGY 599
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPECKN 247
+ D W+LG L + M AG+ P FA+ PN E++L +G+ K +N+S K+
Sbjct: 600 DAACDIWSLGVLFYTMLAGYTP-FANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKD 658
Query: 248 LLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLD 281
LL +L +DP +R + +I H+W D
Sbjct: 659 LLSHMLHMDPHQRYTA-----EQILKHSWITHRD 687
>AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase
protein.
Length = 745
Score = 227 bits (554), Expect = 6e-59
Identities = 116/294 (39%), Positives = 181/294 (61%), Gaps = 10/294 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
F+++K +G G++G+VFLVR K +AMKV++K+ + R+ + +E+ IL +
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTK-MERDILVEVN 131
Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGYS 196
+V+RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+S
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256
S DWW+ G L FEM G PF D N+ +L P+ +S E ++LL+ L + +
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRN 311
Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
P+ R+GS G+ EIK H +F +DW ++ +++ PF P P DT F PE
Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPE 363
Score = 122 bits (293), Expect = 2e-27
Identities = 86/274 (31%), Positives = 143/274 (52%), Gaps = 27/274 (9%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPF 82
+++ + IG G+Y T A+K+++KS +R+ ++ + + +++ Q P
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKS---KRDPSEEIEI---LMRYGQHPN 479
Query: 83 VVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEV 142
++TL F D Y+Y + + GGE+ I K FS+ + ++YLH V
Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539
Query: 143 VHRDIKPENIL-ID---SNGYLKLCDFGFCKVLKKKTWTL---CGTPEYLAPEVITSKGY 195
VHRD+KP NIL +D S +++CDFGF K L+ + L C T ++APEV+ +GY
Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGY 599
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPECKN 247
+ D W+LG L + M AG+ P FA+ PN E++L +G+ K +N+S K+
Sbjct: 600 DAACDIWSLGVLFYTMLAGYTP-FANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKD 658
Query: 248 LLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLD 281
LL +L +DP +R + +I H+W D
Sbjct: 659 LLSHMLHMDPHQRYTA-----EQILKHSWITHRD 687
>AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 214
Score = 226 bits (552), Expect = 1e-58
Identities = 96/194 (49%), Positives = 143/194 (73%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 20 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 79
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 80 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 139
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 140 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 199
Query: 183 EYLAPEVITSKGYS 196
EYLAPE+I SKGY+
Sbjct: 200 EYLAPEIILSKGYN 213
>CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein.
Length = 745
Score = 225 bits (550), Expect = 2e-58
Identities = 116/294 (39%), Positives = 179/294 (60%), Gaps = 10/294 (3%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
F+++K +G G++G+VFLVR K +AMKV++K+ + R + +E+ IL +
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRGRVRTK-MERDILVEVN 131
Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGYS 196
+V+RD+KPENIL+D G++KL DFG K +KK ++ CGT EY+APEV+ +G+S
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256
S DWW+ G L FEM G PF D N+ +L P+ +S E ++LL+ L + +
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQLLSAEAQSLLRMLFKRN 311
Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
P+ R+GS G+ EIK H +F +DW ++ ++ PF P P DT F PE
Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKGEVQPPFKPASGKPDDTFCFDPE 363
Score = 122 bits (293), Expect = 2e-27
Identities = 86/274 (31%), Positives = 143/274 (52%), Gaps = 27/274 (9%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFPF 82
+++ + IG G+Y T A+K+++KS +R+ ++ + + +++ Q P
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKS---KRDPSEEIEI---LMRYGQHPN 479
Query: 83 VVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCEV 142
++TL F D Y+Y + + GGE+ I K FS+ + ++YLH V
Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539
Query: 143 VHRDIKPENIL-ID---SNGYLKLCDFGFCKVLKKKTWTL---CGTPEYLAPEVITSKGY 195
VHRD+KP NIL +D S +++CDFGF K L+ + L C T ++APEV+ +GY
Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGY 599
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPECKN 247
+ D W+LG L + M AG+ P FA+ PN E++L +G+ K +N+S K+
Sbjct: 600 DAACDIWSLGVLFYTMLAGYTP-FANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKD 658
Query: 248 LLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLD 281
LL +L +DP +R + +I H+W D
Sbjct: 659 LLSHMLHMDPHQRYTA-----EQILKHSWITHRD 687
>BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1797
Score = 224 bits (548), Expect = 3e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 510 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 569
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 570 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 629
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 630 GIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 689
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 690 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 749
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 750 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 805
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 806 SEDDTSYF 813
>AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 224 bits (548), Expect = 3e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 395 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 454
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 455 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 514
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 515 GIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 574
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 575 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 634
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 635 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 690
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 691 SEDDTSYF 698
>AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 224 bits (548), Expect = 3e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 510 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 569
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 570 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 629
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 630 GIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 689
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 690 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 749
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 750 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 805
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 806 SEDDTSYF 813
>AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 224 bits (548), Expect = 3e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 395 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 454
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 455 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 514
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 515 GIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 574
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 575 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 634
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 635 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 690
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 691 SEDDTSYF 698
>AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 224 bits (548), Expect = 3e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 510 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 569
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 570 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 629
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 630 GIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 689
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 690 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 749
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 750 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 805
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 806 SEDDTSYF 813
>AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 224 bits (548), Expect = 3e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 510 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 569
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 570 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 629
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 630 GIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 689
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 690 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 749
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 750 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 805
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 806 SEDDTSYF 813
>AL358075-6|CAI21706.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 224 bits (548), Expect = 3e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 395 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 454
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 455 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 514
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 515 GIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 574
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 575 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 634
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 635 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 690
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 691 SEDDTSYF 698
>AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 224 bits (548), Expect = 3e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 510 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 569
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 570 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 629
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 630 GIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 689
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 690 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 749
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 750 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 805
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 806 SEDDTSYF 813
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 223 bits (546), Expect = 5e-58
Identities = 110/294 (37%), Positives = 178/294 (60%), Gaps = 8/294 (2%)
Query: 23 FDIVKAIGNGAYGEVFLVRD---KITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
F+++K +G G+YG+VFLVR +AMKV++K+ + R+ + +E+ IL +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSK-MERDILAEVN 117
Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 118 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 177
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPENIL+D G++K+ DFG K K+ ++ CGT EY+APEV+ +G++
Sbjct: 178 LGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT 237
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256
S DWW+ G L FEM G PF D + +L P+ +S E ++LL+ L + +
Sbjct: 238 QSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRN 297
Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
P R+G+ G+ EIK H +F +DW ++ +++ PF P P DT +F PE
Sbjct: 298 PCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPE 351
Score = 126 bits (304), Expect = 1e-28
Identities = 84/271 (30%), Positives = 146/271 (53%), Gaps = 27/271 (9%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D ++I + IG G+Y K T T +A+K+++KS +R+ ++ + + +L+ Q
Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKS---KRDPSEEIEI---LLRYGQH 466
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D ++Y ++ + GGE+ I + FS+ + ++YLH
Sbjct: 467 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQ 526
Query: 141 EVVHRDIKPENILI-DSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL D +G +++CDFGF K L+ T C T ++APEV+ +
Sbjct: 527 GVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQ 586
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M AG P FA+ P+ E++L +GS K +++S
Sbjct: 587 GYDAACDIWSLGILLYTMLAGFTP-FANGPDDTPEEILARIGSGKYALSGGNWDSISDAA 645
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTW 276
K+++ +L VDP +R+ ++ ++ H W
Sbjct: 646 KDVVSKMLHVDPHQRLTAM-----QVLKHPW 671
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 223 bits (546), Expect = 5e-58
Identities = 110/294 (37%), Positives = 178/294 (60%), Gaps = 8/294 (2%)
Query: 23 FDIVKAIGNGAYGEVFLVRD---KITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
F+++K +G G+YG+VFLVR +AMKV++K+ + R+ + +E+ IL +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSK-MERDILAEVN 117
Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 118 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 177
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPENIL+D G++K+ DFG K K+ ++ CGT EY+APEV+ +G++
Sbjct: 178 LGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT 237
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256
S DWW+ G L FEM G PF D + +L P+ +S E ++LL+ L + +
Sbjct: 238 QSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRN 297
Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
P R+G+ G+ EIK H +F +DW ++ +++ PF P P DT +F PE
Sbjct: 298 PCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPALGRPEDTFHFDPE 351
Score = 126 bits (304), Expect = 1e-28
Identities = 84/271 (30%), Positives = 146/271 (53%), Gaps = 27/271 (9%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D ++I + IG G+Y K T T +A+K+++KS +R+ ++ + + +L+ Q
Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKS---KRDPSEEIEI---LLRYGQH 466
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D ++Y ++ + GGE+ I + FS+ + ++YLH
Sbjct: 467 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQ 526
Query: 141 EVVHRDIKPENILI-DSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL D +G +++CDFGF K L+ T C T ++APEV+ +
Sbjct: 527 GVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQ 586
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M AG P FA+ P+ E++L +GS K +++S
Sbjct: 587 GYDAACDIWSLGILLYTMLAGFTP-FANGPDDTPEEILARIGSGKYALSGGNWDSISDAA 645
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTW 276
K+++ +L VDP +R+ ++ ++ H W
Sbjct: 646 KDVVSKMLHVDPHQRLTAM-----QVLKHPW 671
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 223 bits (546), Expect = 5e-58
Identities = 110/294 (37%), Positives = 178/294 (60%), Gaps = 8/294 (2%)
Query: 23 FDIVKAIGNGAYGEVFLVRD---KITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
F+++K +G G+YG+VFLVR +AMKV++K+ + R+ + +E+ IL +
Sbjct: 60 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSK-MERDILAEVN 118
Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 119 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 178
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPENIL+D G++K+ DFG K K+ ++ CGT EY+APEV+ +G++
Sbjct: 179 LGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT 238
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256
S DWW+ G L FEM G PF D + +L P+ +S E ++LL+ L + +
Sbjct: 239 QSADWWSFGVLMFEMLTGALPFQGKDRKETMSLILKAKLGMPQFLSGEAQSLLRALFKRN 298
Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
P R+G+ G+ EIK H +F +DW ++ +++ PF P P DT +F PE
Sbjct: 299 PCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPALGRPEDTFHFDPE 352
Score = 68.1 bits (159), Expect = 4e-11
Identities = 40/133 (30%), Positives = 71/133 (53%), Gaps = 6/133 (4%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D ++I + IG G+Y K T T +A+K++ KS +R+ ++ + + +L+ Q
Sbjct: 414 DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIGKS---KRDPSEEIEI---LLRYGQH 467
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D ++Y ++ + GGE+ I + FS+ + ++YLH
Sbjct: 468 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQ 527
Query: 141 EVVHRDIKPENIL 153
VVHRD+KP NIL
Sbjct: 528 GVVHRDLKPSNIL 540
>BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein.
Length = 792
Score = 223 bits (546), Expect = 5e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 148 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 207
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 208 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 267
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 268 GIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 327
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 328 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 387
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 388 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 443
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 444 SEDDTSYF 451
>BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein.
Length = 792
Score = 223 bits (546), Expect = 5e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 148 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 207
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 208 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 267
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 268 GIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 327
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 328 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 387
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 388 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 443
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 444 SEDDTSYF 451
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 223 bits (546), Expect = 5e-58
Identities = 110/294 (37%), Positives = 178/294 (60%), Gaps = 8/294 (2%)
Query: 23 FDIVKAIGNGAYGEVFLVRD---KITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
F+++K +G G+YG+VFLVR +AMKV++K+ + R+ + +E+ IL +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSK-MERDILAEVN 117
Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 118 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 177
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPENIL+D G++K+ DFG K K+ ++ CGT EY+APEV+ +G++
Sbjct: 178 LGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT 237
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256
S DWW+ G L FEM G PF D + +L P+ +S E ++LL+ L + +
Sbjct: 238 QSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRN 297
Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
P R+G+ G+ EIK H +F +DW ++ +++ PF P P DT +F PE
Sbjct: 298 PCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPE 351
Score = 126 bits (304), Expect = 1e-28
Identities = 84/271 (30%), Positives = 146/271 (53%), Gaps = 27/271 (9%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D ++I + IG G+Y K T T +A+K+++KS +R+ ++ + + +L+ Q
Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKS---KRDPSEEIEI---LLRYGQH 466
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D ++Y ++ + GGE+ I + FS+ + ++YLH
Sbjct: 467 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQ 526
Query: 141 EVVHRDIKPENILI-DSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL D +G +++CDFGF K L+ T C T ++APEV+ +
Sbjct: 527 GVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQ 586
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M AG P FA+ P+ E++L +GS K +++S
Sbjct: 587 GYDAACDIWSLGILLYTMLAGFTP-FANGPDDTPEEILARIGSGKYALSGGNWDSISDAA 645
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTW 276
K+++ +L VDP +R+ ++ ++ H W
Sbjct: 646 KDVVSKMLHVDPHQRLTAM-----QVLKHPW 671
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 223 bits (546), Expect = 5e-58
Identities = 110/294 (37%), Positives = 178/294 (60%), Gaps = 8/294 (2%)
Query: 23 FDIVKAIGNGAYGEVFLVRD---KITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
F+++K +G G+YG+VFLVR +AMKV++K+ + R+ + +E+ IL +
Sbjct: 59 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSK-MERDILAEVN 117
Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 118 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 177
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPENIL+D G++K+ DFG K K+ ++ CGT EY+APEV+ +G++
Sbjct: 178 LGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT 237
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256
S DWW+ G L FEM G PF D + +L P+ +S E ++LL+ L + +
Sbjct: 238 QSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRN 297
Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
P R+G+ G+ EIK H +F +DW ++ +++ PF P P DT +F PE
Sbjct: 298 PCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPE 351
Score = 126 bits (304), Expect = 1e-28
Identities = 84/271 (30%), Positives = 146/271 (53%), Gaps = 27/271 (9%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D ++I + IG G+Y K T T +A+K+++KS +R+ ++ + + +L+ Q
Sbjct: 413 DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKS---KRDPSEEIEI---LLRYGQH 466
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D ++Y ++ + GGE+ I + FS+ + ++YLH
Sbjct: 467 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQ 526
Query: 141 EVVHRDIKPENILI-DSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL D +G +++CDFGF K L+ T C T ++APEV+ +
Sbjct: 527 GVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQ 586
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M AG P FA+ P+ E++L +GS K +++S
Sbjct: 587 GYDAACDIWSLGILLYTMLAGFTP-FANGPDDTPEEILARIGSGKYALSGGNWDSISDAA 645
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTW 276
K+++ +L VDP +R+ ++ ++ H W
Sbjct: 646 KDVVSKMLHVDPHQRLTAM-----QVLKHPW 671
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 223 bits (546), Expect = 5e-58
Identities = 110/294 (37%), Positives = 178/294 (60%), Gaps = 8/294 (2%)
Query: 23 FDIVKAIGNGAYGEVFLVRD---KITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
F+++K +G G+YG+VFLVR +AMKV++K+ + R+ + +E+ IL +
Sbjct: 132 FELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSK-MERDILAEVN 190
Query: 80 FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHY 139
PF+V L AF+ LY IL ++ GG++FT + K +F++ KFY +++ LAL++LH
Sbjct: 191 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHS 250
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYS 196
+++RD+KPENIL+D G++K+ DFG K K+ ++ CGT EY+APEV+ +G++
Sbjct: 251 LGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT 310
Query: 197 FSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVD 256
S DWW+ G L FEM G PF D + +L P+ +S E ++LL+ L + +
Sbjct: 311 QSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRN 370
Query: 257 PSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF-PE 309
P R+G+ G+ EIK H +F +DW ++ +++ PF P P DT +F PE
Sbjct: 371 PCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPE 424
Score = 126 bits (304), Expect = 1e-28
Identities = 84/271 (30%), Positives = 146/271 (53%), Gaps = 27/271 (9%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
D ++I + IG G+Y K T T +A+K+++KS +R+ ++ + + +L+ Q
Sbjct: 486 DGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKS---KRDPSEEIEI---LLRYGQH 539
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P ++TL + D ++Y ++ + GGE+ I + FS+ + ++YLH
Sbjct: 540 PNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQ 599
Query: 141 EVVHRDIKPENILI-DSNG---YLKLCDFGFCKVLKKKT---WTLCGTPEYLAPEVITSK 193
VVHRD+KP NIL D +G +++CDFGF K L+ T C T ++APEV+ +
Sbjct: 600 GVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQ 659
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP------ENMSPEC 245
GY + D W+LG L + M AG P FA+ P+ E++L +GS K +++S
Sbjct: 660 GYDAACDIWSLGILLYTMLAGFTP-FANGPDDTPEEILARIGSGKYALSGGNWDSISDAA 718
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTW 276
K+++ +L VDP +R+ ++ ++ H W
Sbjct: 719 KDVVSKMLHVDPHQRLTAM-----QVLKHPW 744
>AB047005-1|BAB40778.1| 1734|Homo sapiens MAST205 protein.
Length = 1734
Score = 223 bits (546), Expect = 5e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 510 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 569
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 570 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 629
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 630 GIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 689
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 690 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 749
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 750 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 805
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 806 SEDDTSYF 813
>AB018350-1|BAA34527.2| 1329|Homo sapiens KIAA0807 protein protein.
Length = 1329
Score = 223 bits (546), Expect = 5e-58
Identities = 120/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+ +K I NGAYG VFLVR K T AMK + K ++ RN + +E+ IL +
Sbjct: 41 EDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 100
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV++ +F +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 101 PFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 160
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 161 GIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 220
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 221 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDE 280
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ P+ ++L LL +P +R+G+ G YE+K H +F GLDW + QK A F+P
Sbjct: 281 ALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQK--AEFIPQLE 336
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 337 SEDDTSYF 344
>M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase
alpha-II protein.
Length = 502
Score = 222 bits (543), Expect = 1e-57
Identities = 107/292 (36%), Positives = 177/292 (60%), Gaps = 7/292 (2%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVVER-NHAKHLILEKKILQCI 78
F++++ +G G YG+VF VR T AMKV++K+++V H E+ IL+ +
Sbjct: 68 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 127
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+V L AF+ LY IL Y++GGE+F +++ GIF + FY +++ +AL +LH
Sbjct: 128 KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLH 187
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENI+++ G++KL DFG CK T T CGT EY+APE++ G+
Sbjct: 188 QKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGH 247
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ +VDWW+LG L ++M G PPF + K +K+L P ++ E ++LLK LL+
Sbjct: 248 NRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKR 307
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+ + R+G+ G E+++H +F ++W+ + +K+ PF P+ S D S F
Sbjct: 308 NAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQF 359
>M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase
alpha-I protein.
Length = 525
Score = 222 bits (543), Expect = 1e-57
Identities = 107/292 (36%), Positives = 177/292 (60%), Gaps = 7/292 (2%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVVER-NHAKHLILEKKILQCI 78
F++++ +G G YG+VF VR T AMKV++K+++V H E+ IL+ +
Sbjct: 91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 150
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+V L AF+ LY IL Y++GGE+F +++ GIF + FY +++ +AL +LH
Sbjct: 151 KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLH 210
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENI+++ G++KL DFG CK T T CGT EY+APE++ G+
Sbjct: 211 QKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGH 270
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ +VDWW+LG L ++M G PPF + K +K+L P ++ E ++LLK LL+
Sbjct: 271 NRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKR 330
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+ + R+G+ G E+++H +F ++W+ + +K+ PF P+ S D S F
Sbjct: 331 NAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQF 382
>BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein.
Length = 451
Score = 222 bits (543), Expect = 1e-57
Identities = 107/292 (36%), Positives = 177/292 (60%), Gaps = 7/292 (2%)
Query: 23 FDIVKAIGNGAYGEVFLVRDKI---TFTYHAMKVVEKSVVVER-NHAKHLILEKKILQCI 78
F++++ +G G YG+VF VR T AMKV++K+++V H E+ IL+ +
Sbjct: 91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 150
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+V L AF+ LY IL Y++GGE+F +++ GIF + FY +++ +AL +LH
Sbjct: 151 KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLH 210
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGY 195
+++RD+KPENI+++ G++KL DFG CK T T CGT EY+APE++ G+
Sbjct: 211 QKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGH 270
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+ +VDWW+LG L ++M G PPF + K +K+L P ++ E ++LLK LL+
Sbjct: 271 NRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKR 330
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+ + R+G+ G E+++H +F ++W+ + +K+ PF P+ S D S F
Sbjct: 331 NAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQF 382
>AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 209
Score = 220 bits (538), Expect = 5e-57
Identities = 94/191 (49%), Positives = 140/191 (73%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 19 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 78
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 79 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 138
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 139 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 198
Query: 183 EYLAPEVITSK 193
EYLAPE+I SK
Sbjct: 199 EYLAPEIILSK 209
>AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human
serine-threonine protein kinase R31240_1 protein.
Length = 1237
Score = 220 bits (538), Expect = 5e-57
Identities = 119/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DFD +K I NGAYG V+LVR + T AMK + K ++ RN + +E+ IL +
Sbjct: 13 NDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 72
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV + +F+ +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 73 PFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNY 132
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 133 GIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 192
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 193 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDE 252
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ E + L+ LLQ +P R+G+ GG +E+K H++F LDW + QK A F+P
Sbjct: 253 ALPTEAQLLISSLLQTNPLVRLGA--GGAFEVKQHSFFRDLDWTGLLRQK--AEFIPHLE 308
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 309 SEDDTSYF 316
>AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein.
Length = 1583
Score = 220 bits (538), Expect = 5e-57
Identities = 119/308 (38%), Positives = 173/308 (56%), Gaps = 25/308 (8%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DFD +K I NGAYG V+LVR + T AMK + K ++ RN + +E+ IL +
Sbjct: 385 NDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 444
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PFVV + +F+ +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 445 PFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNY 504
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTP 182
+VHRD+KP+N+LI S G++KL DFG K+ L T L CGTP
Sbjct: 505 GIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 564
Query: 183 EYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN-- 240
EY+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 565 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDE 624
Query: 241 -MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICS 299
+ E + L+ LLQ +P R+G+ GG +E+K H++F LDW + QK A F+P
Sbjct: 625 ALPTEAQLLISSLLQTNPLVRLGA--GGAFEVKQHSFFRDLDWTGLLRQK--AEFIPHLE 680
Query: 300 SPGDTSNF 307
S DTS F
Sbjct: 681 SEDDTSYF 688
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 219 bits (536), Expect = 8e-57
Identities = 115/319 (36%), Positives = 184/319 (57%), Gaps = 14/319 (4%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KE N + S + DFD+++ IG G+Y +V LVR K T +AMKVV+K +V +
Sbjct: 225 KEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDD 284
Query: 63 NHAKHLILEKKIL-QCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDS 121
+ EK + Q PF+V L F+ L+F++ Y+ GG++ ++Q+ +
Sbjct: 285 EDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEE 344
Query: 122 LTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV-LK--KKTWTL 178
+FY++++ LAL YLH +++RD+K +N+L+DS G++KL D+G CK L+ T T
Sbjct: 345 HARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTF 404
Query: 179 CGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPF----FASDPNK-----LYEK 229
CGTP Y+APE++ + Y FSVDWWALG L FEM AG PF + +P++ L++
Sbjct: 405 CGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQV 464
Query: 230 VLVGSYKCPENMSPECKNLLKGLLQVDPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQ 288
+L + P +MS + ++LK L DP +R+G L + G +I+ H +F +DW + +
Sbjct: 465 ILEKQIRIPRSMSVKAASVLKSFLNKDPKERLGCLPQTGFADIQGHPFFRNVDWDMMEQK 524
Query: 289 KLIAPFVPICSSPGDTSNF 307
+++ PF P S NF
Sbjct: 525 QVVPPFKPNISGEFGLDNF 543
>AY830839-1|AAW52510.1| 2434|Homo sapiens serine/threonine protein
kinase protein.
Length = 2434
Score = 219 bits (535), Expect = 1e-56
Identities = 117/307 (38%), Positives = 174/307 (56%), Gaps = 25/307 (8%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81
DF+ +K I NGAYG V+ VR K + AMK + K ++ RN + +E+ IL + P
Sbjct: 380 DFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENP 439
Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141
FVV++ +F+ +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 440 FVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYG 499
Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTPE 183
+VHRD+KP+N+L+ S G++KL DFG KV L T L CGTPE
Sbjct: 500 IVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPE 559
Query: 184 YLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--- 240
Y+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 560 YIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEA 619
Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300
P+ ++L+ LL+ +P +R+G+ GG YE+K H +F LDW ++ QK A F+P S
Sbjct: 620 PPPDAQDLITLLLRQNPLERLGT--GGAYEVKQHRFFRSLDWNSLLRQK--AEFIPQLES 675
Query: 301 PGDTSNF 307
DTS F
Sbjct: 676 EDDTSYF 682
>AB002301-1|BAA20762.1| 2137|Homo sapiens KIAA0303 protein.
Length = 2137
Score = 219 bits (535), Expect = 1e-56
Identities = 117/307 (38%), Positives = 174/307 (56%), Gaps = 25/307 (8%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81
DF+ +K I NGAYG V+ VR K + AMK + K ++ RN + +E+ IL + P
Sbjct: 83 DFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENP 142
Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141
FVV++ +F+ +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 143 FVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYG 202
Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKV-LKKKTWTL-----------------CGTPE 183
+VHRD+KP+N+L+ S G++KL DFG KV L T L CGTPE
Sbjct: 203 IVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPE 262
Query: 184 YLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--- 240
Y+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 263 YIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEA 322
Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300
P+ ++L+ LL+ +P +R+G+ GG YE+K H +F LDW ++ QK A F+P S
Sbjct: 323 PPPDAQDLITLLLRQNPLERLGT--GGAYEVKQHRFFRSLDWNSLLRQK--AEFIPQLES 378
Query: 301 PGDTSNF 307
DTS F
Sbjct: 379 EDDTSYF 385
>U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein.
Length = 984
Score = 218 bits (533), Expect = 2e-56
Identities = 103/296 (34%), Positives = 175/296 (59%), Gaps = 7/296 (2%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78
+ DF +G G +G+V L K T A+K ++K +V R+ L+ EK+I + +
Sbjct: 654 LQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVN 713
Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136
+ PF+V L F+ ++ F++ Y AGG++ +I +FS+ FYA+ V+L L+Y
Sbjct: 714 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHT-DVFSEPRAVFYAACVVLGLQY 772
Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193
LH ++V+RD+K +N+L+D+ G++K+ DFG CK +T T CGTPE+LAPEV+T
Sbjct: 773 LHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTET 832
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253
Y+ +VDWW LG L +EM G PF D ++++ ++ + P +S E ++++ LL
Sbjct: 833 SYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLL 892
Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
+ +P +R+G+ + ++K H +F +DW A+ +K+ PF+P D SNF +
Sbjct: 893 RRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDD 948
>S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein.
Length = 984
Score = 218 bits (533), Expect = 2e-56
Identities = 103/296 (34%), Positives = 175/296 (59%), Gaps = 7/296 (2%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78
+ DF +G G +G+V L K T A+K ++K +V R+ L+ EK+I + +
Sbjct: 654 LQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVN 713
Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136
+ PF+V L F+ ++ F++ Y AGG++ +I +FS+ FYA+ V+L L+Y
Sbjct: 714 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHT-DVFSEPRAVFYAACVVLGLQY 772
Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193
LH ++V+RD+K +N+L+D+ G++K+ DFG CK +T T CGTPE+LAPEV+T
Sbjct: 773 LHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTET 832
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253
Y+ +VDWW LG L +EM G PF D ++++ ++ + P +S E ++++ LL
Sbjct: 833 SYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLL 892
Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
+ +P +R+G+ + ++K H +F +DW A+ +K+ PF+P D SNF +
Sbjct: 893 RRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDD 948
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 218 bits (533), Expect = 2e-56
Identities = 105/293 (35%), Positives = 177/293 (60%), Gaps = 5/293 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
+D+F+ ++ +G G++G+V L R K T +A+KV++K V+++ + + + EK+IL +
Sbjct: 352 IDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLAR 411
Query: 80 -FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+ L F+ L+F++ ++ GG++ +IQK F ++ +FYA+++I AL +LH
Sbjct: 412 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLH 471
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D G+ KL DFG CK T T CGTP+Y+APE++ Y
Sbjct: 472 DKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY 531
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+VDWWA+G L +EM GH PF A + + L+E +L P + + +LK +
Sbjct: 532 GPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTK 591
Query: 256 DPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+P+ R+GSL +GG + I H +F +DW + H+++ PF P S D SNF
Sbjct: 592 NPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNF 644
>AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein.
Length = 984
Score = 218 bits (533), Expect = 2e-56
Identities = 103/296 (34%), Positives = 175/296 (59%), Gaps = 7/296 (2%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78
+ DF +G G +G+V L K T A+K ++K +V R+ L+ EK+I + +
Sbjct: 654 LQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVN 713
Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136
+ PF+V L F+ ++ F++ Y AGG++ +I +FS+ FYA+ V+L L+Y
Sbjct: 714 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHT-DVFSEPRAVFYAACVVLGLQY 772
Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193
LH ++V+RD+K +N+L+D+ G++K+ DFG CK +T T CGTPE+LAPEV+T
Sbjct: 773 LHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTET 832
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253
Y+ +VDWW LG L +EM G PF D ++++ ++ + P +S E ++++ LL
Sbjct: 833 SYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLL 892
Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
+ +P +R+G+ + ++K H +F +DW A+ +K+ PF+P D SNF +
Sbjct: 893 RRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDD 948
>X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha
mRNA for protein kinase C alpha. ).
Length = 672
Score = 218 bits (532), Expect = 3e-56
Identities = 98/282 (34%), Positives = 176/282 (62%), Gaps = 5/282 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81
DF+ + +G G++G+V L K T +A+K+++K VV++ + + ++EK++L + P
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 82 -FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
F+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ + L +LH
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 457
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGYSF 197
+++RD+K +N+++DS G++K+ DFG CK T T CGTP+Y+APE+I + Y
Sbjct: 458 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGK 517
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
SVDWWA G L +EM AG PPF D ++L++ ++ + P+++S E ++ KGL+ P
Sbjct: 518 SVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHP 577
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP-IC 298
+KR+G G +++ H +F +DW+ + ++++ PF P +C
Sbjct: 578 AKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVC 619
>BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 218 bits (532), Expect = 3e-56
Identities = 98/282 (34%), Positives = 176/282 (62%), Gaps = 5/282 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81
DF+ + +G G++G+V L K T +A+K+++K VV++ + + ++EK++L + P
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 82 -FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
F+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ + L +LH
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 457
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGYSF 197
+++RD+K +N+++DS G++K+ DFG CK T T CGTP+Y+APE+I + Y
Sbjct: 458 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGK 517
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
SVDWWA G L +EM AG PPF D ++L++ ++ + P+++S E ++ KGL+ P
Sbjct: 518 SVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHP 577
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP-IC 298
+KR+G G +++ H +F +DW+ + ++++ PF P +C
Sbjct: 578 AKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVC 619
>BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 218 bits (532), Expect = 3e-56
Identities = 98/282 (34%), Positives = 176/282 (62%), Gaps = 5/282 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81
DF+ + +G G++G+V L K T +A+K+++K VV++ + + ++EK++L + P
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 82 -FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
F+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ + L +LH
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 457
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGYSF 197
+++RD+K +N+++DS G++K+ DFG CK T T CGTP+Y+APE+I + Y
Sbjct: 458 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGK 517
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
SVDWWA G L +EM AG PPF D ++L++ ++ + P+++S E ++ KGL+ P
Sbjct: 518 SVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHP 577
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP-IC 298
+KR+G G +++ H +F +DW+ + ++++ PF P +C
Sbjct: 578 AKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVC 619
>AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6
protein protein.
Length = 672
Score = 217 bits (531), Expect = 3e-56
Identities = 100/290 (34%), Positives = 177/290 (61%), Gaps = 5/290 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81
DF+ + +G G++G+V L K T +A+K+++K VV++ + + ++EK++L + P
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 82 -FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
F+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ + L +LH
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKR 457
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK---TWTLCGTPEYLAPEVITSKGYSF 197
+++RD+K +N+++DS G++K+ DFG CK T T CGTP+Y+APE+I + Y
Sbjct: 458 GIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGK 517
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
SVDWWA G L +EM AG PPF D ++L++ ++ + P+++S E ++ KGL+ P
Sbjct: 518 SVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSVCKGLMTKHP 577
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+KR+G G +++ H +F +DW+ + ++++ PF P G NF
Sbjct: 578 AKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVRGKG-AENF 626
>M80335-1|AAA60094.1| 207|Homo sapiens protein kinase A-alpha
protein.
Length = 207
Score = 217 bits (530), Expect = 4e-56
Identities = 92/191 (48%), Positives = 138/191 (72%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ +D F+ +K +G G++G V LV+ K T ++AMK+++K VV+
Sbjct: 7 KEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKL 66
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ +FKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 67 KQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 126
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 127 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTP 186
Query: 183 EYLAPEVITSK 193
EYLAPE+I SK
Sbjct: 187 EYLAPEIILSK 197
>U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein.
Length = 942
Score = 217 bits (529), Expect = 6e-56
Identities = 105/297 (35%), Positives = 177/297 (59%), Gaps = 7/297 (2%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DF + +G G +G+V L + + A+K ++K +V R+ + L+ EK+IL +
Sbjct: 611 TLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAV 670
Query: 79 Q---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135
PF+V L F+ ++ F++ Y AGG++ +I +FS+ FY++ V+L L+
Sbjct: 671 TSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHS-DVFSEPRAIFYSACVVLGLQ 729
Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITS 192
+LH ++V+RD+K +N+L+D+ GY+K+ DFG CK +T T CGTPE+LAPEV+T
Sbjct: 730 FLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTD 789
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
Y+ +VDWW LG L +EM G PF D ++++ ++ + P +S E +++ L
Sbjct: 790 TSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRL 849
Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
L+ +P +R+GS + ++K +F L W+A+ ++L PFVP S D SNF E
Sbjct: 850 LRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDE 906
>S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein.
Length = 942
Score = 217 bits (529), Expect = 6e-56
Identities = 105/297 (35%), Positives = 177/297 (59%), Gaps = 7/297 (2%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DF + +G G +G+V L + + A+K ++K +V R+ + L+ EK+IL +
Sbjct: 611 TLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAV 670
Query: 79 Q---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135
PF+V L F+ ++ F++ Y AGG++ +I +FS+ FY++ V+L L+
Sbjct: 671 TSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHS-DVFSEPRAIFYSACVVLGLQ 729
Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITS 192
+LH ++V+RD+K +N+L+D+ GY+K+ DFG CK +T T CGTPE+LAPEV+T
Sbjct: 730 FLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTD 789
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
Y+ +VDWW LG L +EM G PF D ++++ ++ + P +S E +++ L
Sbjct: 790 TSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRL 849
Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
L+ +P +R+GS + ++K +F L W+A+ ++L PFVP S D SNF E
Sbjct: 850 LRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDE 906
>D26181-1|BAA05169.1| 942|Homo sapiens PKN protein.
Length = 942
Score = 217 bits (529), Expect = 6e-56
Identities = 105/297 (35%), Positives = 177/297 (59%), Gaps = 7/297 (2%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DF + +G G +G+V L + + A+K ++K +V R+ + L+ EK+IL +
Sbjct: 611 TLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAV 670
Query: 79 Q---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135
PF+V L F+ ++ F++ Y AGG++ +I +FS+ FY++ V+L L+
Sbjct: 671 TSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHS-DVFSEPRAIFYSACVVLGLQ 729
Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITS 192
+LH ++V+RD+K +N+L+D+ GY+K+ DFG CK +T T CGTPE+LAPEV+T
Sbjct: 730 FLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTD 789
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
Y+ +VDWW LG L +EM G PF D ++++ ++ + P +S E +++ L
Sbjct: 790 TSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRL 849
Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
L+ +P +R+GS + ++K +F L W+A+ ++L PFVP S D SNF E
Sbjct: 850 LRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDE 906
>BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein.
Length = 936
Score = 217 bits (529), Expect = 6e-56
Identities = 103/296 (34%), Positives = 174/296 (58%), Gaps = 7/296 (2%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78
+ DF +G G +G+V L K T A+K ++K +V R+ L+ EK+I + +
Sbjct: 606 LQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVN 665
Query: 79 --QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136
+ PF+V L F+ ++ F++ Y AGG++ +I +FS+ FYA+ V+L L+Y
Sbjct: 666 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHT-DVFSEPRAVFYAACVVLGLQY 724
Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193
LH ++V+RD+K +N+L+D+ G +K+ DFG CK +T T CGTPE+LAPEV+T
Sbjct: 725 LHEHKIVYRDLKLDNLLLDTEGLVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTET 784
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253
Y+ +VDWW LG L +EM G PF D ++++ ++ + P +S E ++++ LL
Sbjct: 785 SYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLL 844
Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
+ +P +R+G+ + ++K H +F +DW A+ +K+ PF+P D SNF +
Sbjct: 845 RRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDD 900
>BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 5 protein.
Length = 549
Score = 217 bits (529), Expect = 6e-56
Identities = 116/306 (37%), Positives = 186/306 (60%), Gaps = 17/306 (5%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKI----TFTYHAMKVVEKSVVVER-NHAKHLILEKKI 74
+++F+++K +G GAYG+VFLVR KI T +AMKV++K+ +V++ +H E+++
Sbjct: 46 IENFELLKVLGTGAYGKVFLVR-KISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQV 104
Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
L+ I Q PF+VTL AF+ L+ IL YI GGE+FT++ + F++ + Y +++LA
Sbjct: 105 LEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLA 164
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEV 189
LE+LH +++RDIK ENIL+DSNG++ L DFG K ++ ++ CGT EY+AP++
Sbjct: 165 LEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDI 224
Query: 190 IT--SKGYSFSVDWWALGDLSFEMEAGHPPFFA----SDPNKLYEKVLVGSYKCPENMSP 243
+ G+ +VDWW+LG L +E+ G PF + ++ ++L P+ MS
Sbjct: 225 VRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSA 284
Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303
K+L++ LL DP KR+G EIK H +F ++W + +K+ APF P+ D
Sbjct: 285 LAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELD 344
Query: 304 TSNFPE 309
SNF E
Sbjct: 345 VSNFAE 350
Score = 62.9 bits (146), Expect = 2e-09
Identities = 41/140 (29%), Positives = 70/140 (50%), Gaps = 8/140 (5%)
Query: 12 DAPIYDKTVDDFDIV-KAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLIL 70
D+P Y D D+ K +G G++ K + A+K++ K + E N K +
Sbjct: 416 DSPFYQHY--DLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRM--EANTQKEITA 471
Query: 71 EKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQV 130
K C P +V L F D L+ + ++ + GGE+F I+K FS++ + ++
Sbjct: 472 LKL---CEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKL 528
Query: 131 ILALEYLHYCEVVHRDIKPE 150
+ A+ ++H VVHRD+KPE
Sbjct: 529 VSAVSHMHDVGVVHRDLKPE 548
>AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kinase
protein.
Length = 809
Score = 217 bits (529), Expect = 6e-56
Identities = 116/306 (37%), Positives = 186/306 (60%), Gaps = 17/306 (5%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKI----TFTYHAMKVVEKSVVVER-NHAKHLILEKKI 74
+++F+++K +G GAYG+VFLVR KI T +AMKV++K+ +V++ +H E+++
Sbjct: 46 IENFELLKVLGTGAYGKVFLVR-KISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQV 104
Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
L+ I Q PF+VTL AF+ L+ IL YI GGE+FT++ + F++ + Y +++LA
Sbjct: 105 LEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLA 164
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEV 189
LE+LH +++RDIK ENIL+DSNG++ L DFG K ++ ++ CGT EY+AP++
Sbjct: 165 LEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDI 224
Query: 190 IT--SKGYSFSVDWWALGDLSFEMEAGHPPFFA----SDPNKLYEKVLVGSYKCPENMSP 243
+ G+ +VDWW+LG L +E+ G PF + ++ ++L P+ MS
Sbjct: 225 VRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSA 284
Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303
K+L++ LL DP KR+G EIK H +F ++W + +K+ APF P+ D
Sbjct: 285 LAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELD 344
Query: 304 TSNFPE 309
SNF E
Sbjct: 345 VSNFAE 350
Score = 116 bits (279), Expect = 1e-25
Identities = 82/268 (30%), Positives = 137/268 (51%), Gaps = 25/268 (9%)
Query: 12 DAPIYDKTVDDFDIV-KAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLIL 70
D+P Y D D+ K +G G++ K + +K++ K + E N K +
Sbjct: 416 DSPFYQHY--DLDLKDKPLGEGSFSICRKCVHKKSNQALQVKIISKRM--EANTQKEITA 471
Query: 71 EKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQV 130
K C P +V L F D L+ + ++ + GGE+F ++K FS++ + ++
Sbjct: 472 LKL---CEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKL 528
Query: 131 ILALEYLHYCEVVHRDIKPENILI-DSNGYL--KLCDFGFCKVL---KKKTWTLCGTPEY 184
+ AL ++H VVHRD+KPEN+L D N L K+ DFGF ++ + T C T
Sbjct: 529 VSALSHMHDLGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHS 588
Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPN-------KLYEKVLVGSY-- 235
PE++ GY S D W+LG + + M +G PF + D + ++ +K+ G +
Sbjct: 589 CRPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSF 648
Query: 236 --KCPENMSPECKNLLKGLLQVDPSKRI 261
+ +N+S E K+L++GLL VDP+KR+
Sbjct: 649 EGEAWKNVSQEAKDLIQGLLTVDPNKRL 676
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase
RLPK protein.
Length = 802
Score = 217 bits (529), Expect = 6e-56
Identities = 116/306 (37%), Positives = 186/306 (60%), Gaps = 17/306 (5%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKI----TFTYHAMKVVEKSVVVER-NHAKHLILEKKI 74
+++F+++K +G GAYG+VFLVR KI T +AMKV++K+ +V++ +H E+++
Sbjct: 46 IENFELLKVLGTGAYGKVFLVR-KISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQV 104
Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
L+ I Q PF+VTL AF+ L+ IL YI GGE+FT++ + F++ + Y +++LA
Sbjct: 105 LEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLA 164
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEV 189
LE+LH +++RDIK ENIL+DSNG++ L DFG K ++ ++ CGT EY+AP++
Sbjct: 165 LEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDI 224
Query: 190 IT--SKGYSFSVDWWALGDLSFEMEAGHPPFFA----SDPNKLYEKVLVGSYKCPENMSP 243
+ G+ +VDWW+LG L +E+ G PF + ++ ++L P+ MS
Sbjct: 225 VRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSA 284
Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303
K+L++ LL DP KR+G EIK H +F ++W + +K+ APF P+ D
Sbjct: 285 LAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELD 344
Query: 304 TSNFPE 309
SNF E
Sbjct: 345 VSNFAE 350
Score = 124 bits (299), Expect = 4e-28
Identities = 85/268 (31%), Positives = 140/268 (52%), Gaps = 25/268 (9%)
Query: 12 DAPIYDKTVDDFDIV-KAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLIL 70
D+P Y D D+ K +G G++ K + A+K++ K + E N K +
Sbjct: 416 DSPFYQHY--DLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRM--EANTQKEITA 471
Query: 71 EKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQV 130
K C P +V L F D L+ + ++ + GGE+F I+K FS++ + ++
Sbjct: 472 LKL---CEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKL 528
Query: 131 ILALEYLHYCEVVHRDIKPENILI-DSNGYL--KLCDFGFCKVL---KKKTWTLCGTPEY 184
+ A+ ++H VVHRD+KPEN+L D N L K+ DFGF ++ + T C T Y
Sbjct: 529 VSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHY 588
Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPN-------KLYEKVLVGSY-- 235
APE++ GY S D W+LG + + M +G PF + D + ++ +K+ G +
Sbjct: 589 AAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSF 648
Query: 236 --KCPENMSPECKNLLKGLLQVDPSKRI 261
+ +N+S E K+L++GLL VDP+KR+
Sbjct: 649 EGEAWKNVSQEAKDLIQGLLTVDPNKRL 676
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 217 bits (529), Expect = 6e-56
Identities = 116/306 (37%), Positives = 186/306 (60%), Gaps = 17/306 (5%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKI----TFTYHAMKVVEKSVVVER-NHAKHLILEKKI 74
+++F+++K +G GAYG+VFLVR KI T +AMKV++K+ +V++ +H E+++
Sbjct: 46 IENFELLKVLGTGAYGKVFLVR-KISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQV 104
Query: 75 LQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
L+ I Q PF+VTL AF+ L+ IL YI GGE+FT++ + F++ + Y +++LA
Sbjct: 105 LEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLA 164
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL----KKKTWTLCGTPEYLAPEV 189
LE+LH +++RDIK ENIL+DSNG++ L DFG K ++ ++ CGT EY+AP++
Sbjct: 165 LEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDI 224
Query: 190 IT--SKGYSFSVDWWALGDLSFEMEAGHPPFFA----SDPNKLYEKVLVGSYKCPENMSP 243
+ G+ +VDWW+LG L +E+ G PF + ++ ++L P+ MS
Sbjct: 225 VRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSA 284
Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303
K+L++ LL DP KR+G EIK H +F ++W + +K+ APF P+ D
Sbjct: 285 LAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELD 344
Query: 304 TSNFPE 309
SNF E
Sbjct: 345 VSNFAE 350
Score = 124 bits (299), Expect = 4e-28
Identities = 85/268 (31%), Positives = 140/268 (52%), Gaps = 25/268 (9%)
Query: 12 DAPIYDKTVDDFDIV-KAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLIL 70
D+P Y D D+ K +G G++ K + A+K++ K + E N K +
Sbjct: 416 DSPFYQHY--DLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRM--EANTQKEITA 471
Query: 71 EKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQV 130
K C P +V L F D L+ + ++ + GGE+F I+K FS++ + ++
Sbjct: 472 LKL---CEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKL 528
Query: 131 ILALEYLHYCEVVHRDIKPENILI-DSNGYL--KLCDFGFCKVL---KKKTWTLCGTPEY 184
+ A+ ++H VVHRD+KPEN+L D N L K+ DFGF ++ + T C T Y
Sbjct: 529 VSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHY 588
Query: 185 LAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPN-------KLYEKVLVGSY-- 235
APE++ GY S D W+LG + + M +G PF + D + ++ +K+ G +
Sbjct: 589 AAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSF 648
Query: 236 --KCPENMSPECKNLLKGLLQVDPSKRI 261
+ +N+S E K+L++GLL VDP+KR+
Sbjct: 649 EGEAWKNVSQEAKDLIQGLLTVDPNKRL 676
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 216 bits (528), Expect = 8e-56
Identities = 105/293 (35%), Positives = 176/293 (60%), Gaps = 5/293 (1%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
+D+F+ ++ +G G++G+V L R K T +A+KV++K V++ + + + EK+IL +
Sbjct: 351 IDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLAR 410
Query: 80 -FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+ L F+ L+F++ ++ GG++ +IQK F ++ +FYA+++I AL +LH
Sbjct: 411 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLH 470
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D G+ KL DFG CK T T CGTP+Y+APE++ Y
Sbjct: 471 DKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY 530
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+VDWWA+G L +EM GH PF A + + L+E +L P + + +LK +
Sbjct: 531 GPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTK 590
Query: 256 DPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
+P+ R+GSL +GG + I H +F +DW + H+++ PF P S D SNF
Sbjct: 591 NPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNF 643
>BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein.
Length = 942
Score = 216 bits (528), Expect = 8e-56
Identities = 105/297 (35%), Positives = 177/297 (59%), Gaps = 7/297 (2%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DF + +G G +G+V L + + A+K ++K +V R+ + L+ EK+IL +
Sbjct: 611 TLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAV 670
Query: 79 Q---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135
PF+V L F+ ++ F++ Y AGG++ +I +FS+ FY++ V+L L+
Sbjct: 671 TSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHS-DVFSEPRAIFYSACVVLGLQ 729
Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITS 192
+LH ++V+RD+K +N+L+D+ GY+K+ DFG CK +T T CGTPE+LAPEV+T
Sbjct: 730 FLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTD 789
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
Y+ +VDWW LG L +EM G PF D ++++ ++ + P +S E +++ L
Sbjct: 790 TSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRL 849
Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
L+ +P +R+GS + ++K +F L W+A+ ++L PFVP S D SNF E
Sbjct: 850 LRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDISNFDE 906
>X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta I. ).
Length = 671
Score = 216 bits (527), Expect = 1e-55
Identities = 102/290 (35%), Positives = 174/290 (60%), Gaps = 4/290 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI-QF 80
DF+ + +G G++G+V L K T +A+K+++K VV++ + + ++EK++L +
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ + L +L
Sbjct: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+K +N+++DS G++K+ DFG CK T T CGTP+Y+APE+I + Y
Sbjct: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGK 520
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
SVDWWA G L +EM AG PF D ++L++ ++ + P++MS E + KGL+ P
Sbjct: 521 SVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHP 580
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
KR+G G +IK H +F +DW+ + +++ P+ P DTSNF
Sbjct: 581 GKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNF 630
>AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (5'
partial) splice form_1 protein.
Length = 494
Score = 216 bits (527), Expect = 1e-55
Identities = 102/290 (35%), Positives = 174/290 (60%), Gaps = 4/290 (1%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI-QF 80
DF+ + +G G++G+V L K T +A+K+++K VV++ + + ++EK++L +
Sbjct: 164 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 223
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ + L +L
Sbjct: 224 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 283
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+K +N+++DS G++K+ DFG CK T T CGTP+Y+APE+I + Y
Sbjct: 284 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGK 343
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
SVDWWA G L +EM AG PF D ++L++ ++ + P++MS E + KGL+ P
Sbjct: 344 SVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHP 403
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
KR+G G +IK H +F +DW+ + +++ P+ P DTSNF
Sbjct: 404 GKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNF 453
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 215 bits (526), Expect = 1e-55
Identities = 113/319 (35%), Positives = 183/319 (57%), Gaps = 14/319 (4%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KE N + S + DFD+++ IG G+Y +V LVR K T +AMKVV+K +V +
Sbjct: 225 KEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDD 284
Query: 63 NHAKHLILEKKIL-QCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDS 121
+ EK + Q PF+V L F+ L+F++ Y+ GG++ ++Q+ +
Sbjct: 285 EDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEE 344
Query: 122 LTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV-LK--KKTWTL 178
+FY++++ LAL YLH +++RD+K +N+L+DS G++KL D+G CK L+ T T
Sbjct: 345 HARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTF 404
Query: 179 CGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPF----FASDPNK-----LYEK 229
CGTP Y+APE++ + Y FSVDWWALG L FEM AG PF + +P++ L++
Sbjct: 405 CGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQV 464
Query: 230 VLVGSYKCPENMSPECKNLLKGLLQVDPSKRIG-SLKGGIYEIKSHTWFNGLDWQAIFHQ 288
+L + P ++S + ++LK L DP +R+G + G +I+ H +F +DW + +
Sbjct: 465 ILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQK 524
Query: 289 KLIAPFVPICSSPGDTSNF 307
+++ PF P S NF
Sbjct: 525 QVVPPFKPNISGEFGLDNF 543
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 215 bits (526), Expect = 1e-55
Identities = 113/319 (35%), Positives = 183/319 (57%), Gaps = 14/319 (4%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KE N + S + DFD+++ IG G+Y +V LVR K T +AMKVV+K +V +
Sbjct: 225 KEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDD 284
Query: 63 NHAKHLILEKKIL-QCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDS 121
+ EK + Q PF+V L F+ L+F++ Y+ GG++ ++Q+ +
Sbjct: 285 EDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEE 344
Query: 122 LTKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV-LK--KKTWTL 178
+FY++++ LAL YLH +++RD+K +N+L+DS G++KL D+G CK L+ T T
Sbjct: 345 HARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTF 404
Query: 179 CGTPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPF----FASDPNK-----LYEK 229
CGTP Y+APE++ + Y FSVDWWALG L FEM AG PF + +P++ L++
Sbjct: 405 CGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQV 464
Query: 230 VLVGSYKCPENMSPECKNLLKGLLQVDPSKRIG-SLKGGIYEIKSHTWFNGLDWQAIFHQ 288
+L + P ++S + ++LK L DP +R+G + G +I+ H +F +DW + +
Sbjct: 465 ILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQK 524
Query: 289 KLIAPFVPICSSPGDTSNF 307
+++ PF P S NF
Sbjct: 525 QVVPPFKPNISGEFGLDNF 543
>AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 197
Score = 215 bits (526), Expect = 1e-55
Identities = 91/187 (48%), Positives = 137/187 (73%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 11 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 70
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 71 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 130
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 131 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 190
Query: 183 EYLAPEV 189
EYLAPE+
Sbjct: 191 EYLAPEI 197
>X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon
protein.
Length = 737
Score = 215 bits (525), Expect = 2e-55
Identities = 116/324 (35%), Positives = 187/324 (57%), Gaps = 13/324 (4%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
+D+F+ +K +G G++G+V L K +A+KV++K V+++ + + EK+IL +
Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
Query: 80 -FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
P++ L F+ L+F++ Y+ GG++ IQ+ F + ++FYA++V AL +LH
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKK-KTWTLCGTPEYLAPEVITSKGY 195
V++RD+K +NIL+D+ G+ KL DFG CK +L T T CGTP+Y+APE++ Y
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
SVDWWALG L +EM AG PPF A + + L+E +L P +S E ++LK +
Sbjct: 585 GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTK 644
Query: 256 DPSKRIGSL--KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE---I 310
+P KR+G + + G IK H +F +DW + +K+ PF P + D +NF +
Sbjct: 645 NPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTR 704
Query: 311 PQPKLRKVS----KYLYEEEFAEF 330
+P L V K + +EEF F
Sbjct: 705 EEPVLTLVDEAIVKQINQEEFKGF 728
>BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 215 bits (525), Expect = 2e-55
Identities = 116/324 (35%), Positives = 187/324 (57%), Gaps = 13/324 (4%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
+D+F+ +K +G G++G+V L K +A+KV++K V+++ + + EK+IL +
Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
Query: 80 -FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
P++ L F+ L+F++ Y+ GG++ IQ+ F + ++FYA++V AL +LH
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKK-KTWTLCGTPEYLAPEVITSKGY 195
V++RD+K +NIL+D+ G+ KL DFG CK +L T T CGTP+Y+APE++ Y
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
SVDWWALG L +EM AG PPF A + + L+E +L P +S E ++LK +
Sbjct: 585 GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTK 644
Query: 256 DPSKRIGSL--KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE---I 310
+P KR+G + + G IK H +F +DW + +K+ PF P + D +NF +
Sbjct: 645 NPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTR 704
Query: 311 PQPKLRKVS----KYLYEEEFAEF 330
+P L V K + +EEF F
Sbjct: 705 EEPVLTLVDEAIVKQINQEEFKGF 728
>BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 215 bits (525), Expect = 2e-55
Identities = 116/324 (35%), Positives = 187/324 (57%), Gaps = 13/324 (4%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQ 79
+D+F+ +K +G G++G+V L K +A+KV++K V+++ + + EK+IL +
Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
Query: 80 -FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
P++ L F+ L+F++ Y+ GG++ IQ+ F + ++FYA++V AL +LH
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKK-KTWTLCGTPEYLAPEVITSKGY 195
V++RD+K +NIL+D+ G+ KL DFG CK +L T T CGTP+Y+APE++ Y
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
SVDWWALG L +EM AG PPF A + + L+E +L P +S E ++LK +
Sbjct: 585 GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTK 644
Query: 256 DPSKRIGSL--KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE---I 310
+P KR+G + + G IK H +F +DW + +K+ PF P + D +NF +
Sbjct: 645 NPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTR 704
Query: 311 PQPKLRKVS----KYLYEEEFAEF 330
+P L V K + +EEF F
Sbjct: 705 EEPVLTLVDEAIVKQINQEEFKGF 728
>X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein
kinase protein.
Length = 479
Score = 214 bits (522), Expect = 4e-55
Identities = 104/297 (35%), Positives = 176/297 (59%), Gaps = 7/297 (2%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DF + +G G +G+V L + + A+K ++K +V R+ + L+ EK+IL +
Sbjct: 148 TLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAV 207
Query: 79 Q---FPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALE 135
PF+V L F+ ++ F++ Y AGG++ +I +FS+ FY++ V+L L+
Sbjct: 208 TSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLILHIHS-DVFSEPRAIFYSACVVLGLQ 266
Query: 136 YLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITS 192
+LH ++V+RD+K +N+L+D+ GY+K+ DFG CK +T T CGTPE+LAPEV+T
Sbjct: 267 FLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTD 326
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
Y+ +VDWW LG L +EM G P D ++++ ++ + P +S E +++ L
Sbjct: 327 TSYTRAVDWWGLGVLLYEMLVGESPLPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRL 386
Query: 253 LQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
L+ +P +R+GS + ++K +F L W+A+ ++L PFVP S D SNF E
Sbjct: 387 LRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDISNFDE 443
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 212 bits (518), Expect = 1e-54
Identities = 113/306 (36%), Positives = 178/306 (58%), Gaps = 16/306 (5%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+D+++VK IG GA+GEV LVR K T +AMK++ K +++R+ + E+ I+
Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 133
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P+VV L AF+D+ YLY ++ Y+ GG++ + Y + + +FY ++V+LAL+ +H
Sbjct: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWARFYTAEVVLALDAIHSM 192
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLC----GTPEYLAPEVITSKG-- 194
+HRD+KP+N+L+D +G+LKL DFG C + K+ C GTP+Y++PEV+ S+G
Sbjct: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD 252
Query: 195 --YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPE--NMSPECKNL 248
Y DWW++G +EM G PF+A Y K++ S P+ ++S E KNL
Sbjct: 253 GYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNL 312
Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFP 308
+ L D R+G + G+ EIK H +F W + +AP VP SS DTSNF
Sbjct: 313 ICAFL-TDREVRLG--RNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFD 369
Query: 309 EIPQPK 314
++ + K
Sbjct: 370 DLEEDK 375
>L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 212 bits (517), Expect = 2e-54
Identities = 108/307 (35%), Positives = 182/307 (59%), Gaps = 9/307 (2%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
+ NK+ I K ++DF + K +G G++G+VFL K T + A+K ++K VV+ +
Sbjct: 363 ELNKERPSLQIKLK-IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDD 421
Query: 65 AKHLILEKKILQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLT 123
+ ++EK++L + PF+ + F+ L+F++ Y+ GG++ +IQ F S
Sbjct: 422 VECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRA 481
Query: 124 KFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCG 180
FYA+++IL L++LH +V+RD+K +NIL+D +G++K+ DFG CK + KT T CG
Sbjct: 482 TFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCG 541
Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240
TP+Y+APE++ + Y+ SVDWW+ G L +EM G PF D +L+ + + + P
Sbjct: 542 TPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW 601
Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300
+ E K+LL L +P KR+G ++G +I+ H F ++W+ + +++ PF P S
Sbjct: 602 LEKEAKDLLVKLFVREPEKRLG-VRG---DIRQHPLFREINWEELERKEIDPPFRPKVKS 657
Query: 301 PGDTSNF 307
P D SNF
Sbjct: 658 PFDCSNF 664
>L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 212 bits (517), Expect = 2e-54
Identities = 108/307 (35%), Positives = 182/307 (59%), Gaps = 9/307 (2%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
+ NK+ I K ++DF + K +G G++G+VFL K T + A+K ++K VV+ +
Sbjct: 363 ELNKERPSLQIKLK-IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDD 421
Query: 65 AKHLILEKKILQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLT 123
+ ++EK++L + PF+ + F+ L+F++ Y+ GG++ +IQ F S
Sbjct: 422 VECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRA 481
Query: 124 KFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCG 180
FYA+++IL L++LH +V+RD+K +NIL+D +G++K+ DFG CK + KT T CG
Sbjct: 482 TFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCG 541
Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240
TP+Y+APE++ + Y+ SVDWW+ G L +EM G PF D +L+ + + + P
Sbjct: 542 TPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW 601
Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300
+ E K+LL L +P KR+G ++G +I+ H F ++W+ + +++ PF P S
Sbjct: 602 LEKEAKDLLVKLFVREPEKRLG-VRG---DIRQHPLFREINWEELERKEIDPPFRPKVKS 657
Query: 301 PGDTSNF 307
P D SNF
Sbjct: 658 PFDCSNF 664
>BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 212 bits (517), Expect = 2e-54
Identities = 108/307 (35%), Positives = 182/307 (59%), Gaps = 9/307 (2%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
+ NK+ I K ++DF + K +G G++G+VFL K T + A+K ++K VV+ +
Sbjct: 363 ELNKERPSLQIKLK-IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDD 421
Query: 65 AKHLILEKKILQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLT 123
+ ++EK++L + PF+ + F+ L+F++ Y+ GG++ +IQ F S
Sbjct: 422 VECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRA 481
Query: 124 KFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCG 180
FYA+++IL L++LH +V+RD+K +NIL+D +G++K+ DFG CK + KT T CG
Sbjct: 482 TFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCG 541
Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240
TP+Y+APE++ + Y+ SVDWW+ G L +EM G PF D +L+ + + + P
Sbjct: 542 TPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW 601
Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300
+ E K+LL L +P KR+G ++G +I+ H F ++W+ + +++ PF P S
Sbjct: 602 LEKEAKDLLVKLFVREPEKRLG-VRG---DIRQHPLFREINWEELERKEIDPPFRPKVKS 657
Query: 301 PGDTSNF 307
P D SNF
Sbjct: 658 PFDCSNF 664
>BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 212 bits (517), Expect = 2e-54
Identities = 108/307 (35%), Positives = 182/307 (59%), Gaps = 9/307 (2%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
+ NK+ I K ++DF + K +G G++G+VFL K T + A+K ++K VV+ +
Sbjct: 363 ELNKERPSLQIKLK-IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDD 421
Query: 65 AKHLILEKKILQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLT 123
+ ++EK++L + PF+ + F+ L+F++ Y+ GG++ +IQ F S
Sbjct: 422 VECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRA 481
Query: 124 KFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCG 180
FYA+++IL L++LH +V+RD+K +NIL+D +G++K+ DFG CK + KT T CG
Sbjct: 482 TFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCG 541
Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240
TP+Y+APE++ + Y+ SVDWW+ G L +EM G PF D +L+ + + + P
Sbjct: 542 TPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW 601
Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300
+ E K+LL L +P KR+G ++G +I+ H F ++W+ + +++ PF P S
Sbjct: 602 LEKEAKDLLVKLFVREPEKRLG-VRG---DIRQHPLFREINWEELERKEIDPPFRPKVKS 657
Query: 301 PGDTSNF 307
P D SNF
Sbjct: 658 PFDCSNF 664
>AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 212 bits (517), Expect = 2e-54
Identities = 108/307 (35%), Positives = 182/307 (59%), Gaps = 9/307 (2%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
+ NK+ I K ++DF + K +G G++G+VFL K T + A+K ++K VV+ +
Sbjct: 363 ELNKERPSLQIKLK-IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDD 421
Query: 65 AKHLILEKKILQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLT 123
+ ++EK++L + PF+ + F+ L+F++ Y+ GG++ +IQ F S
Sbjct: 422 VECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRA 481
Query: 124 KFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCG 180
FYA+++IL L++LH +V+RD+K +NIL+D +G++K+ DFG CK + KT T CG
Sbjct: 482 TFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCG 541
Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240
TP+Y+APE++ + Y+ SVDWW+ G L +EM G PF D +L+ + + + P
Sbjct: 542 TPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW 601
Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300
+ E K+LL L +P KR+G ++G +I+ H F ++W+ + +++ PF P S
Sbjct: 602 LEKEAKDLLVKLFVREPEKRLG-VRG---DIRQHPLFREINWEELERKEIDPPFRPKVKS 657
Query: 301 PGDTSNF 307
P D SNF
Sbjct: 658 PFDCSNF 664
>AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 212 bits (517), Expect = 2e-54
Identities = 108/307 (35%), Positives = 182/307 (59%), Gaps = 9/307 (2%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
+ NK+ I K ++DF + K +G G++G+VFL K T + A+K ++K VV+ +
Sbjct: 135 ELNKERPSLQIKLK-IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDD 193
Query: 65 AKHLILEKKILQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLT 123
+ ++EK++L + PF+ + F+ L+F++ Y+ GG++ +IQ F S
Sbjct: 194 VECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRA 253
Query: 124 KFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCG 180
FYA+++IL L++LH +V+RD+K +NIL+D +G++K+ DFG CK + KT T CG
Sbjct: 254 TFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCG 313
Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240
TP+Y+APE++ + Y+ SVDWW+ G L +EM G PF D +L+ + + + P
Sbjct: 314 TPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW 373
Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300
+ E K+LL L +P KR+G ++G +I+ H F ++W+ + +++ PF P S
Sbjct: 374 LEKEAKDLLVKLFVREPEKRLG-VRG---DIRQHPLFREINWEELERKEIDPPFRPKVKS 429
Query: 301 PGDTSNF 307
P D SNF
Sbjct: 430 PFDCSNF 436
>AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 212 bits (517), Expect = 2e-54
Identities = 108/307 (35%), Positives = 182/307 (59%), Gaps = 9/307 (2%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
+ NK+ I K ++DF + K +G G++G+VFL K T + A+K ++K VV+ +
Sbjct: 363 ELNKERPSLQIKLK-IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDD 421
Query: 65 AKHLILEKKILQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLT 123
+ ++EK++L + PF+ + F+ L+F++ Y+ GG++ +IQ F S
Sbjct: 422 VECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRA 481
Query: 124 KFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCG 180
FYA+++IL L++LH +V+RD+K +NIL+D +G++K+ DFG CK + KT T CG
Sbjct: 482 TFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCG 541
Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240
TP+Y+APE++ + Y+ SVDWW+ G L +EM G PF D +L+ + + + P
Sbjct: 542 TPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW 601
Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300
+ E K+LL L +P KR+G ++G +I+ H F ++W+ + +++ PF P S
Sbjct: 602 LEKEAKDLLVKLFVREPEKRLG-VRG---DIRQHPLFREINWEELERKEIDPPFRPKVKS 657
Query: 301 PGDTSNF 307
P D SNF
Sbjct: 658 PFDCSNF 664
>AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 212 bits (517), Expect = 2e-54
Identities = 108/307 (35%), Positives = 182/307 (59%), Gaps = 9/307 (2%)
Query: 5 DFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNH 64
+ NK+ I K ++DF + K +G G++G+VFL K T + A+K ++K VV+ +
Sbjct: 135 ELNKERPSLQIKLK-IEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDD 193
Query: 65 AKHLILEKKILQCI-QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLT 123
+ ++EK++L + PF+ + F+ L+F++ Y+ GG++ +IQ F S
Sbjct: 194 VECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRA 253
Query: 124 KFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCG 180
FYA+++IL L++LH +V+RD+K +NIL+D +G++K+ DFG CK + KT T CG
Sbjct: 254 TFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCG 313
Query: 181 TPEYLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN 240
TP+Y+APE++ + Y+ SVDWW+ G L +EM G PF D +L+ + + + P
Sbjct: 314 TPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRW 373
Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300
+ E K+LL L +P KR+G ++G +I+ H F ++W+ + +++ PF P S
Sbjct: 374 LEKEAKDLLVKLFVREPEKRLG-VRG---DIRQHPLFREINWEELERKEIDPPFRPKVKS 429
Query: 301 PGDTSNF 307
P D SNF
Sbjct: 430 PFDCSNF 436
>Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta
protein.
Length = 584
Score = 210 bits (512), Expect = 7e-54
Identities = 106/300 (35%), Positives = 173/300 (57%), Gaps = 12/300 (4%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCI 78
+ DFD+++ IG G+Y +V LVR K +AMKVV+K +V + + EK + Q
Sbjct: 241 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 300
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L F+ L+ ++ Y+ GG++ ++Q+ + +FYA+++ +AL +LH
Sbjct: 301 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 360
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D++G++KL D+G CK T T CGTP Y+APE++ + Y
Sbjct: 361 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 420
Query: 196 SFSVDWWALGDLSFEMEAGHPPF--FASDPNK-----LYEKVLVGSYKCPENMSPECKNL 248
FSVDWWALG L FEM AG PF +P+ L++ +L + P +S + ++
Sbjct: 421 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 480
Query: 249 LKGLLQVDPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
LKG L DP +R+G + G +IKSH +F +DW + ++ + PF P + NF
Sbjct: 481 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 540
>BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (512), Expect = 7e-54
Identities = 106/300 (35%), Positives = 173/300 (57%), Gaps = 12/300 (4%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCI 78
+ DFD+++ IG G+Y +V LVR K +AMKVV+K +V + + EK + Q
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L F+ L+ ++ Y+ GG++ ++Q+ + +FYA+++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D++G++KL D+G CK T T CGTP Y+APE++ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 196 SFSVDWWALGDLSFEMEAGHPPF--FASDPNK-----LYEKVLVGSYKCPENMSPECKNL 248
FSVDWWALG L FEM AG PF +P+ L++ +L + P +S + ++
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 249 LKGLLQVDPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
LKG L DP +R+G + G +IKSH +F +DW + ++ + PF P + NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
>BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (512), Expect = 7e-54
Identities = 106/300 (35%), Positives = 173/300 (57%), Gaps = 12/300 (4%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCI 78
+ DFD+++ IG G+Y +V LVR K +AMKVV+K +V + + EK + Q
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L F+ L+ ++ Y+ GG++ ++Q+ + +FYA+++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D++G++KL D+G CK T T CGTP Y+APE++ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 196 SFSVDWWALGDLSFEMEAGHPPF--FASDPNK-----LYEKVLVGSYKCPENMSPECKNL 248
FSVDWWALG L FEM AG PF +P+ L++ +L + P +S + ++
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 249 LKGLLQVDPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
LKG L DP +R+G + G +IKSH +F +DW + ++ + PF P + NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
>BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (512), Expect = 7e-54
Identities = 106/300 (35%), Positives = 173/300 (57%), Gaps = 12/300 (4%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCI 78
+ DFD+++ IG G+Y +V LVR K +AMKVV+K +V + + EK + Q
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L F+ L+ ++ Y+ GG++ ++Q+ + +FYA+++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D++G++KL D+G CK T T CGTP Y+APE++ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 196 SFSVDWWALGDLSFEMEAGHPPF--FASDPNK-----LYEKVLVGSYKCPENMSPECKNL 248
FSVDWWALG L FEM AG PF +P+ L++ +L + P +S + ++
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 249 LKGLLQVDPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
LKG L DP +R+G + G +IKSH +F +DW + ++ + PF P + NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
>AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (512), Expect = 7e-54
Identities = 106/300 (35%), Positives = 173/300 (57%), Gaps = 12/300 (4%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCI 78
+ DFD+++ IG G+Y +V LVR K +AMKVV+K +V + + EK + Q
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L F+ L+ ++ Y+ GG++ ++Q+ + +FYA+++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D++G++KL D+G CK T T CGTP Y+APE++ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 196 SFSVDWWALGDLSFEMEAGHPPF--FASDPNK-----LYEKVLVGSYKCPENMSPECKNL 248
FSVDWWALG L FEM AG PF +P+ L++ +L + P +S + ++
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 249 LKGLLQVDPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
LKG L DP +R+G + G +IKSH +F +DW + ++ + PF P + NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
>AL590822-6|CAI12484.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (512), Expect = 7e-54
Identities = 106/300 (35%), Positives = 173/300 (57%), Gaps = 12/300 (4%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCI 78
+ DFD+++ IG G+Y +V LVR K +AMKVV+K +V + + EK + Q
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L F+ L+ ++ Y+ GG++ ++Q+ + +FYA+++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D++G++KL D+G CK T T CGTP Y+APE++ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 196 SFSVDWWALGDLSFEMEAGHPPF--FASDPNK-----LYEKVLVGSYKCPENMSPECKNL 248
FSVDWWALG L FEM AG PF +P+ L++ +L + P +S + ++
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 249 LKGLLQVDPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
LKG L DP +R+G + G +IKSH +F +DW + ++ + PF P + NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
>AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (512), Expect = 7e-54
Identities = 106/300 (35%), Positives = 173/300 (57%), Gaps = 12/300 (4%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCI 78
+ DFD+++ IG G+Y +V LVR K +AMKVV+K +V + + EK + Q
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L F+ L+ ++ Y+ GG++ ++Q+ + +FYA+++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D++G++KL D+G CK T T CGTP Y+APE++ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 196 SFSVDWWALGDLSFEMEAGHPPF--FASDPNK-----LYEKVLVGSYKCPENMSPECKNL 248
FSVDWWALG L FEM AG PF +P+ L++ +L + P +S + ++
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 249 LKGLLQVDPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
LKG L DP +R+G + G +IKSH +F +DW + ++ + PF P + NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
>L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta
protein.
Length = 592
Score = 209 bits (511), Expect = 9e-54
Identities = 106/300 (35%), Positives = 172/300 (57%), Gaps = 12/300 (4%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKIL-QCI 78
+ DFD+++ IG G Y +V LVR K +AMKVV+K +V + + EK + Q
Sbjct: 249 LQDFDLIRVIGRGTYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
PF+V L F+ L+ ++ Y+ GG++ ++Q+ + +FYA+++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D++G++KL D+G CK T T CGTP Y+APE++ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 196 SFSVDWWALGDLSFEMEAGHPPF--FASDPNK-----LYEKVLVGSYKCPENMSPECKNL 248
FSVDWWALG L FEM AG PF +P+ L++ +L + P +S + ++
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 249 LKGLLQVDPSKRIGSL-KGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
LKG L DP +R+G + G +IKSH +F +DW + ++ + PF P + NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
>X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta II. ).
Length = 673
Score = 209 bits (510), Expect = 1e-53
Identities = 104/319 (32%), Positives = 184/319 (57%), Gaps = 10/319 (3%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI-QF 80
DF+ + +G G++G+V L K T +A+K+++K VV++ + + ++EK++L +
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ + L +L
Sbjct: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+K +N+++DS G++K+ DFG CK T T CGTP+Y+APE+I + Y
Sbjct: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGK 520
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
SVDWWA G L +EM AG PF D ++L++ ++ + P++MS E + KGL+ P
Sbjct: 521 SVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHP 580
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP-ICSSPGDT-----SNFPEIP 311
KR+G G +IK H +F +DW+ + +++ P+ P C + + P +
Sbjct: 581 GKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVL 640
Query: 312 QPKLRKVSKYLYEEEFAEF 330
P ++V + + + EF F
Sbjct: 641 TPPDQEVIRNIDQSEFEGF 659
>M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II
type protein.
Length = 673
Score = 209 bits (510), Expect = 1e-53
Identities = 104/319 (32%), Positives = 184/319 (57%), Gaps = 10/319 (3%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI-QF 80
DF+ + +G G++G+V L K T +A+K+++K VV++ + + ++EK++L +
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ + L +L
Sbjct: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+K +N+++DS G++K+ DFG CK T T CGTP+Y+APE+I + Y
Sbjct: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGK 520
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
SVDWWA G L +EM AG PF D ++L++ ++ + P++MS E + KGL+ P
Sbjct: 521 SVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHP 580
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP-ICSSPGDT-----SNFPEIP 311
KR+G G +IK H +F +DW+ + +++ P+ P C + + P +
Sbjct: 581 GKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVL 640
Query: 312 QPKLRKVSKYLYEEEFAEF 330
P ++V + + + EF F
Sbjct: 641 TPPDQEVIRNIDQSEFEGF 659
>BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta 1
protein.
Length = 673
Score = 209 bits (510), Expect = 1e-53
Identities = 104/319 (32%), Positives = 184/319 (57%), Gaps = 10/319 (3%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI-QF 80
DF+ + +G G++G+V L K T +A+K+++K VV++ + + ++EK++L +
Sbjct: 341 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 400
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ + L +L
Sbjct: 401 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 460
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+K +N+++DS G++K+ DFG CK T T CGTP+Y+APE+I + Y
Sbjct: 461 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGK 520
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
SVDWWA G L +EM AG PF D ++L++ ++ + P++MS E + KGL+ P
Sbjct: 521 SVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHP 580
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP-ICSSPGDT-----SNFPEIP 311
KR+G G +IK H +F +DW+ + +++ P+ P C + + P +
Sbjct: 581 GKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVL 640
Query: 312 QPKLRKVSKYLYEEEFAEF 330
P ++V + + + EF F
Sbjct: 641 TPPDQEVIRNIDQSEFEGF 659
>AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (5'
partial) splice form_ protein.
Length = 496
Score = 209 bits (510), Expect = 1e-53
Identities = 104/319 (32%), Positives = 184/319 (57%), Gaps = 10/319 (3%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI-QF 80
DF+ + +G G++G+V L K T +A+K+++K VV++ + + ++EK++L +
Sbjct: 164 DFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKP 223
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
PF+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ + L +L
Sbjct: 224 PFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSK 283
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGYSF 197
+++RD+K +N+++DS G++K+ DFG CK T T CGTP+Y+APE+I + Y
Sbjct: 284 GIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGK 343
Query: 198 SVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQVDP 257
SVDWWA G L +EM AG PF D ++L++ ++ + P++MS E + KGL+ P
Sbjct: 344 SVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHP 403
Query: 258 SKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP-ICSSPGDT-----SNFPEIP 311
KR+G G +IK H +F +DW+ + +++ P+ P C + + P +
Sbjct: 404 GKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVL 463
Query: 312 QPKLRKVSKYLYEEEFAEF 330
P ++V + + + EF F
Sbjct: 464 TPPDQEVIRNIDQSEFEGF 482
>AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein.
Length = 1308
Score = 208 bits (507), Expect = 3e-53
Identities = 112/307 (36%), Positives = 173/307 (56%), Gaps = 25/307 (8%)
Query: 22 DFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQFP 81
DF+ +K I NGAYG V+LVR + T A+K + K ++ RN + + +E+ IL + P
Sbjct: 365 DFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENP 424
Query: 82 FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYCE 141
FVV++ +F+ +L ++ Y+ GG+ T ++ G + + Y ++ +LALEYLH
Sbjct: 425 FVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHNYG 484
Query: 142 VVHRDIKPENILIDSNGYLKLCDFGFCKV-------------LKKKT-----WTLCGTPE 183
+VHRD+KP+N+LI S G++KL DFG K+ ++K +CGTPE
Sbjct: 485 IVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQVCGTPE 544
Query: 184 YLAPEVITSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPEN--- 240
Y+APEVI +GY VDWWA+G + +E G PFF P +L+ +V+ PE
Sbjct: 545 YIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEA 604
Query: 241 MSPECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSS 300
+ + ++L+ LL+ P R+G+ GG +E+K H +F LDW + K A FVP +
Sbjct: 605 LPADAQDLITRLLRQSPLDRLGT--GGTHEVKQHPFFLALDWAGLLRHK--AEFVPQLEA 660
Query: 301 PGDTSNF 307
DTS F
Sbjct: 661 EDDTSYF 667
>D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein.
Length = 1388
Score = 206 bits (504), Expect = 6e-53
Identities = 112/306 (36%), Positives = 176/306 (57%), Gaps = 16/306 (5%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+D+D+VK IG GA+GEV LVR K + +AMK++ K +++R+ + E+ I+
Sbjct: 90 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 149
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P+VV L AF+D+ YLY ++ Y+ GG++ + Y + + KFY ++V+LAL+ +H
Sbjct: 150 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSM 208
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLC----GTPEYLAPEVITSKG-- 194
++HRD+KP+N+L+D +G+LKL DFG C + + C GTP+Y++PEV+ S+G
Sbjct: 209 GLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGD 268
Query: 195 --YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPEN--MSPECKNL 248
Y DWW++G +EM G PF+A Y K++ S PE+ +S KNL
Sbjct: 269 GFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNL 328
Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFP 308
+ L D R+G + G+ EI+ H +F W ++ AP VP SS D+SNF
Sbjct: 329 ICAFL-TDREVRLG--RNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFD 385
Query: 309 EIPQPK 314
+I K
Sbjct: 386 DIEDDK 391
>AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein.
Length = 1337
Score = 206 bits (504), Expect = 6e-53
Identities = 112/306 (36%), Positives = 176/306 (57%), Gaps = 16/306 (5%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+D+D+VK IG GA+GEV LVR K + +AMK++ K +++R+ + E+ I+
Sbjct: 43 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 102
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P+VV L AF+D+ YLY ++ Y+ GG++ + Y + + KFY ++V+LAL+ +H
Sbjct: 103 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSM 161
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLC----GTPEYLAPEVITSKG-- 194
++HRD+KP+N+L+D +G+LKL DFG C + + C GTP+Y++PEV+ S+G
Sbjct: 162 GLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGD 221
Query: 195 --YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPEN--MSPECKNL 248
Y DWW++G +EM G PF+A Y K++ S PE+ +S KNL
Sbjct: 222 GFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNL 281
Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFP 308
+ L D R+G + G+ EI+ H +F W ++ AP VP SS D+SNF
Sbjct: 282 ICAFL-TDREVRLG--RNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFD 338
Query: 309 EIPQPK 314
+I K
Sbjct: 339 DIEDDK 344
>AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta
protein.
Length = 889
Score = 206 bits (504), Expect = 6e-53
Identities = 103/294 (35%), Positives = 173/294 (58%), Gaps = 7/294 (2%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ--- 76
+ DF + +G G +G+V LV+ K T Y+A+K ++K V+ R+ + L EK+IL+
Sbjct: 556 LQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVG 615
Query: 77 CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136
C PF+++L V F+ + + F+ ++ GG++ I + +F + +FY + V+L L++
Sbjct: 616 CTGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIHE-DVFPEPQARFYVACVVLGLQF 674
Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193
LH ++++RD+K +N+L+D+ G+LK+ DFG CK +T T CGTPE+LAPEV+T +
Sbjct: 675 LHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQE 734
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253
Y+ +VDWWALG L +EM G PF ++++ ++ P +S + ++ LL
Sbjct: 735 AYTQAVDWWALGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLL 794
Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
Q P KR+G+ + EIK +F +WQA+ + + PFVP P D F
Sbjct: 795 QKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYF 848
>AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein.
Length = 1428
Score = 206 bits (504), Expect = 6e-53
Identities = 112/306 (36%), Positives = 176/306 (57%), Gaps = 16/306 (5%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+D+D+VK IG GA+GEV LVR K + +AMK++ K +++R+ + E+ I+
Sbjct: 130 EDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 189
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P+VV L AF+D+ YLY ++ Y+ GG++ + Y + + KFY ++V+LAL+ +H
Sbjct: 190 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDV-PEKWAKFYTAEVVLALDAIHSM 248
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLC----GTPEYLAPEVITSKG-- 194
++HRD+KP+N+L+D +G+LKL DFG C + + C GTP+Y++PEV+ S+G
Sbjct: 249 GLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGD 308
Query: 195 --YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPEN--MSPECKNL 248
Y DWW++G +EM G PF+A Y K++ S PE+ +S KNL
Sbjct: 309 GFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNL 368
Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFP 308
+ L D R+G + G+ EI+ H +F W ++ AP VP SS D+SNF
Sbjct: 369 ICAFL-TDREVRLG--RNGVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFD 425
Query: 309 EIPQPK 314
+I K
Sbjct: 426 DIEDDK 431
>L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 204 bits (498), Expect = 3e-52
Identities = 100/294 (34%), Positives = 177/294 (60%), Gaps = 8/294 (2%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ-CI 78
+++F K +G G++G+V L K Y A+K ++K VV+ + + ++EK++L
Sbjct: 346 INNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTMVEKRVLTLAA 405
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+ L F+ +L+F++ ++ GG++ +IQ G F FYA++++ L++LH
Sbjct: 406 ENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLH 465
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D +G++K+ DFG CK + + T CGTP+Y+APE++ Y
Sbjct: 466 SKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKY 525
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+FSVDWW+ G L +EM G PF D ++L+E + V + P ++ E K++L+ L +
Sbjct: 526 TFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFER 585
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
+P+KR+G + G IK H +F ++W + ++L PF P SP D SNF +
Sbjct: 586 EPTKRLG-MTG---NIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQ 635
>L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 204 bits (497), Expect = 4e-52
Identities = 100/294 (34%), Positives = 177/294 (60%), Gaps = 8/294 (2%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ-CI 78
+++F K +G G++G+V L K Y A+K ++K VV+ + + ++EK++L
Sbjct: 346 INNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAA 405
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+ L F+ +L+F++ ++ GG++ +IQ G F FYA++++ L++LH
Sbjct: 406 ENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLH 465
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D +G++K+ DFG CK + + T CGTP+Y+APE++ Y
Sbjct: 466 SKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKY 525
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+FSVDWW+ G L +EM G PF D ++L+E + V + P ++ E K++L+ L +
Sbjct: 526 TFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFER 585
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
+P+KR+G + G IK H +F ++W + ++L PF P SP D SNF +
Sbjct: 586 EPTKRLG-VTG---NIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQ 635
>D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-type
protein.
Length = 626
Score = 204 bits (497), Expect = 4e-52
Identities = 100/294 (34%), Positives = 177/294 (60%), Gaps = 8/294 (2%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ-CI 78
+++F K +G G++G+V L K Y A+K ++K VV+ + + ++EK++L
Sbjct: 296 INNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAA 355
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+ L F+ +L+F++ ++ GG++ +IQ G F FYA++++ L++LH
Sbjct: 356 ENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLH 415
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D +G++K+ DFG CK + + T CGTP+Y+APE++ Y
Sbjct: 416 SKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKY 475
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+FSVDWW+ G L +EM G PF D ++L+E + V + P ++ E K++L+ L +
Sbjct: 476 TFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFER 535
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
+P+KR+G + G IK H +F ++W + ++L PF P SP D SNF +
Sbjct: 536 EPTKRLG-VTG---NIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQ 585
>BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta
protein.
Length = 676
Score = 204 bits (497), Expect = 4e-52
Identities = 100/294 (34%), Positives = 177/294 (60%), Gaps = 8/294 (2%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ-CI 78
+++F K +G G++G+V L K Y A+K ++K VV+ + + ++EK++L
Sbjct: 346 INNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAA 405
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+ L F+ +L+F++ ++ GG++ +IQ G F FYA++++ L++LH
Sbjct: 406 ENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLH 465
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL---KKKTWTLCGTPEYLAPEVITSKGY 195
+++RD+K +N+L+D +G++K+ DFG CK + + T CGTP+Y+APE++ Y
Sbjct: 466 SKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKY 525
Query: 196 SFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLLQV 255
+FSVDWW+ G L +EM G PF D ++L+E + V + P ++ E K++L+ L +
Sbjct: 526 TFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFER 585
Query: 256 DPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFPE 309
+P+KR+G + G IK H +F ++W + ++L PF P SP D SNF +
Sbjct: 586 EPTKRLG-VTG---NIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQ 635
>BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 203 bits (496), Expect = 6e-52
Identities = 101/294 (34%), Positives = 171/294 (58%), Gaps = 7/294 (2%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ--- 76
+ DF + +G G +G+V LV+ K T Y+A+K ++K V+ R+ + L EK+IL+
Sbjct: 556 LQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVG 615
Query: 77 CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136
C PF+++L F+ + + F+ ++ GG++ I + +F + +FY + V+L L++
Sbjct: 616 CTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHE-DVFPEPQARFYVACVVLGLQF 674
Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193
LH ++++RD+K +N+L+D+ G+LK+ DFG CK +T T CGTPE+LAPEV+T +
Sbjct: 675 LHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQE 734
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253
Y+ +VDWW LG L +EM G PF ++++ ++ P +S + ++ LL
Sbjct: 735 AYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLL 794
Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
Q P KR+G+ + EIK +F +WQA+ + + PFVP P D F
Sbjct: 795 QKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYF 848
>AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 203 bits (496), Expect = 6e-52
Identities = 101/294 (34%), Positives = 171/294 (58%), Gaps = 7/294 (2%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQ--- 76
+ DF + +G G +G+V LV+ K T Y+A+K ++K V+ R+ + L EK+IL+
Sbjct: 556 LQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVG 615
Query: 77 CIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEY 136
C PF+++L F+ + + F+ ++ GG++ I + +F + +FY + V+L L++
Sbjct: 616 CTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHE-DVFPEPQARFYVACVVLGLQF 674
Query: 137 LHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKV---LKKKTWTLCGTPEYLAPEVITSK 193
LH ++++RD+K +N+L+D+ G+LK+ DFG CK +T T CGTPE+LAPEV+T +
Sbjct: 675 LHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQE 734
Query: 194 GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGLL 253
Y+ +VDWW LG L +EM G PF ++++ ++ P +S + ++ LL
Sbjct: 735 AYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLL 794
Query: 254 QVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNF 307
Q P KR+G+ + EIK +F +WQA+ + + PFVP P D F
Sbjct: 795 QKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYF 848
>AL022329-1|CAB45657.1| 688|Homo sapiens adrenergic, beta, receptor
kinase 2 protein.
Length = 688
Score = 203 bits (496), Expect = 6e-52
Identities = 106/287 (36%), Positives = 170/287 (59%), Gaps = 10/287 (3%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T+++F + + IG G +GEV+ R T +AMK ++K + + + L L ++I+ +
Sbjct: 187 TMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSL 245
Query: 79 ----QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILAL 134
PF+V + AF L FIL + GG++ ++ ++G+FS+ +FYA+++IL L
Sbjct: 246 VSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGL 305
Query: 135 EYLHYCEVVHRDIKPENILIDSNGYLKLCDFGF-CKVLKKKTWTLCGTPEYLAPEVI-TS 192
E++H VV+RD+KP NIL+D +G+ ++ D G C KKK GT Y+APEV+
Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKG 365
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPF---FASDPNKLYEKVLVGSYKCPENMSPECKNLL 249
Y S DW++LG + F++ GH PF D +++ L + + P+ SPE K+LL
Sbjct: 366 TAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLL 425
Query: 250 KGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296
+GLLQ D SKR+G GG E+K H++F G+DWQ ++ QK P +P
Sbjct: 426 EGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIP 472
>X69117-1|CAA48870.1| 688|Homo sapiens beta-adrenergic kinase 2
protein.
Length = 688
Score = 203 bits (495), Expect = 8e-52
Identities = 106/287 (36%), Positives = 170/287 (59%), Gaps = 10/287 (3%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T+++F + + IG G +GEV+ R T +AMK ++K + + + L L ++I+ +
Sbjct: 187 TMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSL 245
Query: 79 ----QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILAL 134
PF+V + AF L FIL + GG++ ++ ++G+FS+ +FYA+++IL L
Sbjct: 246 VSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGL 305
Query: 135 EYLHYCEVVHRDIKPENILIDSNGYLKLCDFGF-CKVLKKKTWTLCGTPEYLAPEVI-TS 192
E++H VV+RD+KP NIL+D +G+ ++ D G C KKK GT Y+APEV+
Sbjct: 306 EHVHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKG 365
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPF---FASDPNKLYEKVLVGSYKCPENMSPECKNLL 249
Y S DW++LG + F++ GH PF D +++ L + + P+ SPE K+LL
Sbjct: 366 TAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLL 425
Query: 250 KGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296
+GLLQ D SKR+G GG E+K H++F G+DWQ ++ QK P +P
Sbjct: 426 EGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIP 472
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 protein.
Length = 1354
Score = 203 bits (495), Expect = 8e-52
Identities = 111/306 (36%), Positives = 175/306 (57%), Gaps = 16/306 (5%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+D+++VK IG GA+GEV LVR K T +AMK++ K +++R+ + E+ I+
Sbjct: 74 EDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANS 133
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLHYC 140
P+VV L AF+D+ YLY ++ Y+ GG++ + Y + +FY ++V+LAL+ +H
Sbjct: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDA-PEKWARFYTAEVVLALDAIHSM 192
Query: 141 EVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLC----GTPEYLAPEVITSKG-- 194
+H D+KP+N+L+D +G+LKL DFG + K+ C GTP+Y++PEV+ S+G
Sbjct: 193 GFIHGDVKPDNMLLDKSGHLKLADFGTRMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD 252
Query: 195 --YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPE--NMSPECKNL 248
Y DWW++G +EM G PF+A Y K++ S P+ ++S E KNL
Sbjct: 253 GYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNL 312
Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTSNFP 308
+ L D R+G + G+ EIK H +F W + +AP VP SS DTSNF
Sbjct: 313 ICAFL-TDREVRLG--RNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFD 369
Query: 309 EIPQPK 314
++ + K
Sbjct: 370 DLEEDK 375
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 202 bits (492), Expect = 2e-51
Identities = 96/277 (34%), Positives = 167/277 (60%), Gaps = 6/277 (2%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
K +DF K +G G++ V L R+ T +A+K++EK +++ N ++ E+ ++
Sbjct: 50 KRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSR 109
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF V L F+D+ LYF L Y GE+ YI+K G F ++ T+FY ++++ ALEYL
Sbjct: 110 LDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYL 169
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-----KKKTWTLCGTPEYLAPEVITS 192
H ++HRD+KPENIL++ + Y+++ DFG KVL + + + GT +Y++PE++T
Sbjct: 170 HGKGIIHRDLKPENILLNEDMYIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTE 229
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
K S D WALG + +++ AG PPF A + +++K++ Y PE P+ ++L++ L
Sbjct: 230 KSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKL 289
Query: 253 LQVDPSKRIGSLK-GGIYEIKSHTWFNGLDWQAIFHQ 288
L +D +KR+G + G +K+H +F + W+ + Q
Sbjct: 290 LVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 326
>AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 206
Score = 201 bits (491), Expect = 2e-51
Identities = 85/180 (47%), Positives = 130/180 (72%)
Query: 3 KEDFNKKYSDAPIYDKTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVER 62
KEDF KK+ + + ++DF+ K +G G++G V LV+ K T Y+AMK+++K VV+
Sbjct: 27 KEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKL 86
Query: 63 NHAKHLILEKKILQCIQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSL 122
+H + EK+ILQ + FPF+V L+ AFKDN LY ++ Y+ GGEMF+++++ G FS+
Sbjct: 87 KQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 146
Query: 123 TKFYASQVILALEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKKTWTLCGTP 182
+FYA+Q++L EYLH ++++RD+KPEN+LID GY+++ DFGF K +K +TWTLCGTP
Sbjct: 147 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTP 206
>Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma
protein.
Length = 536
Score = 200 bits (489), Expect = 4e-51
Identities = 97/294 (32%), Positives = 171/294 (58%), Gaps = 10/294 (3%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78
+ DF + +G G++G+V L + + +A+K+++K V+V+ + ++EK++L
Sbjct: 187 ISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGG 246
Query: 79 QFP-----FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
+ P F+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ +
Sbjct: 247 RGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIG 306
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVI 190
L +LH +++RD+K +N+++D+ G++K+ DFG CK T T CGTP+Y+APE+I
Sbjct: 307 LFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEII 366
Query: 191 TSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLK 250
+ Y SVDWW+ G L +EM AG PPF D +L++ ++ + P+++S E + K
Sbjct: 367 AYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICK 426
Query: 251 GLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP-ICSSPGD 303
G L P KR+GS G I++H +F +DW+ + ++ PF P C G+
Sbjct: 427 GFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSGE 480
>BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma
protein.
Length = 697
Score = 200 bits (489), Expect = 4e-51
Identities = 97/294 (32%), Positives = 171/294 (58%), Gaps = 10/294 (3%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78
+ DF + +G G++G+V L + + +A+K+++K V+V+ + ++EK++L
Sbjct: 348 ISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGG 407
Query: 79 QFP-----FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
+ P F+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ +
Sbjct: 408 RGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIG 467
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVI 190
L +LH +++RD+K +N+++D+ G++K+ DFG CK T T CGTP+Y+APE+I
Sbjct: 468 LFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEII 527
Query: 191 TSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLK 250
+ Y SVDWW+ G L +EM AG PPF D +L++ ++ + P+++S E + K
Sbjct: 528 AYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICK 587
Query: 251 GLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP-ICSSPGD 303
G L P KR+GS G I++H +F +DW+ + ++ PF P C G+
Sbjct: 588 GFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSGE 641
>AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma
protein.
Length = 697
Score = 200 bits (489), Expect = 4e-51
Identities = 97/294 (32%), Positives = 171/294 (58%), Gaps = 10/294 (3%)
Query: 20 VDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI- 78
+ DF + +G G++G+V L + + +A+K+++K V+V+ + ++EK++L
Sbjct: 348 ISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGG 407
Query: 79 QFP-----FVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILA 133
+ P F+ L F+ LYF++ Y+ GG++ +IQ+ G F + FYA+++ +
Sbjct: 408 RGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIG 467
Query: 134 LEYLHYCEVVHRDIKPENILIDSNGYLKLCDFGFCK---VLKKKTWTLCGTPEYLAPEVI 190
L +LH +++RD+K +N+++D+ G++K+ DFG CK T T CGTP+Y+APE+I
Sbjct: 468 LFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEII 527
Query: 191 TSKGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLK 250
+ Y SVDWW+ G L +EM AG PPF D +L++ ++ + P+++S E + K
Sbjct: 528 AYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICK 587
Query: 251 GLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP-ICSSPGD 303
G L P KR+GS G I++H +F +DW+ + ++ PF P C G+
Sbjct: 588 GFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSGE 641
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 200 bits (487), Expect = 7e-51
Identities = 95/277 (34%), Positives = 167/277 (60%), Gaps = 6/277 (2%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
K +DF K +G G++ V L R+ T +A+K++EK +++ N ++ E+ ++
Sbjct: 77 KRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSR 136
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF V L F+D+ LYF L Y GE+ YI+K G F ++ T+FY ++++ ALEYL
Sbjct: 137 LDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYL 196
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-----KKKTWTLCGTPEYLAPEVITS 192
H ++HRD+KPENIL++ + ++++ DFG KVL + + + GT +Y++PE++T
Sbjct: 197 HGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTE 256
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
K S D WALG + +++ AG PPF A + +++K++ Y PE P+ ++L++ L
Sbjct: 257 KSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKL 316
Query: 253 LQVDPSKRIGSLK-GGIYEIKSHTWFNGLDWQAIFHQ 288
L +D +KR+G + G +K+H +F + W+ + Q
Sbjct: 317 LVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 353
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 200 bits (487), Expect = 7e-51
Identities = 95/277 (34%), Positives = 167/277 (60%), Gaps = 6/277 (2%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
K +DF K +G G++ V L R+ T +A+K++EK +++ N ++ E+ ++
Sbjct: 77 KRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSR 136
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF V L F+D+ LYF L Y GE+ YI+K G F ++ T+FY ++++ ALEYL
Sbjct: 137 LDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYL 196
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-----KKKTWTLCGTPEYLAPEVITS 192
H ++HRD+KPENIL++ + ++++ DFG KVL + + + GT +Y++PE++T
Sbjct: 197 HGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTE 256
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
K S D WALG + +++ AG PPF A + +++K++ Y PE P+ ++L++ L
Sbjct: 257 KSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKL 316
Query: 253 LQVDPSKRIGSLK-GGIYEIKSHTWFNGLDWQAIFHQ 288
L +D +KR+G + G +K+H +F + W+ + Q
Sbjct: 317 LVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 353
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 200 bits (487), Expect = 7e-51
Identities = 95/277 (34%), Positives = 167/277 (60%), Gaps = 6/277 (2%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
K +DF K +G G++ V L R+ T +A+K++EK +++ N ++ E+ ++
Sbjct: 77 KRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSR 136
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF V L F+D+ LYF L Y GE+ YI+K G F ++ T+FY ++++ ALEYL
Sbjct: 137 LDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYL 196
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-----KKKTWTLCGTPEYLAPEVITS 192
H ++HRD+KPENIL++ + ++++ DFG KVL + + + GT +Y++PE++T
Sbjct: 197 HGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTE 256
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
K S D WALG + +++ AG PPF A + +++K++ Y PE P+ ++L++ L
Sbjct: 257 KSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKL 316
Query: 253 LQVDPSKRIGSLK-GGIYEIKSHTWFNGLDWQAIFHQ 288
L +D +KR+G + G +K+H +F + W+ + Q
Sbjct: 317 LVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 353
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 200 bits (487), Expect = 7e-51
Identities = 95/277 (34%), Positives = 167/277 (60%), Gaps = 6/277 (2%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
K +DF K +G G++ V L R+ T +A+K++EK +++ N ++ E+ ++
Sbjct: 77 KRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSR 136
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF V L F+D+ LYF L Y GE+ YI+K G F ++ T+FY ++++ ALEYL
Sbjct: 137 LDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYL 196
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-----KKKTWTLCGTPEYLAPEVITS 192
H ++HRD+KPENIL++ + ++++ DFG KVL + + + GT +Y++PE++T
Sbjct: 197 HGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTE 256
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
K S D WALG + +++ AG PPF A + +++K++ Y PE P+ ++L++ L
Sbjct: 257 KSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKL 316
Query: 253 LQVDPSKRIGSLK-GGIYEIKSHTWFNGLDWQAIFHQ 288
L +D +KR+G + G +K+H +F + W+ + Q
Sbjct: 317 LVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 353
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 200 bits (487), Expect = 7e-51
Identities = 95/277 (34%), Positives = 167/277 (60%), Gaps = 6/277 (2%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
K +DF K +G G++ V L R+ T +A+K++EK +++ N ++ E+ ++
Sbjct: 69 KRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSR 128
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF V L F+D+ LYF L Y GE+ YI+K G F ++ T+FY ++++ ALEYL
Sbjct: 129 LDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYL 188
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-----KKKTWTLCGTPEYLAPEVITS 192
H ++HRD+KPENIL++ + ++++ DFG KVL + + + GT +Y++PE++T
Sbjct: 189 HGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTE 248
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
K S D WALG + +++ AG PPF A + +++K++ Y PE P+ ++L++ L
Sbjct: 249 KSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKL 308
Query: 253 LQVDPSKRIGSLK-GGIYEIKSHTWFNGLDWQAIFHQ 288
L +D +KR+G + G +K+H +F + W+ + Q
Sbjct: 309 LVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 345
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 200 bits (487), Expect = 7e-51
Identities = 95/277 (34%), Positives = 167/277 (60%), Gaps = 6/277 (2%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
K +DF K +G G++ V L R+ T +A+K++EK +++ N ++ E+ ++
Sbjct: 115 KRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSR 174
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF V L F+D+ LYF L Y GE+ YI+K G F ++ T+FY ++++ ALEYL
Sbjct: 175 LDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYL 234
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-----KKKTWTLCGTPEYLAPEVITS 192
H ++HRD+KPENIL++ + ++++ DFG KVL + + + GT +Y++PE++T
Sbjct: 235 HGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTE 294
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
K S D WALG + +++ AG PPF A + +++K++ Y PE P+ ++L++ L
Sbjct: 295 KSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKL 354
Query: 253 LQVDPSKRIGSLK-GGIYEIKSHTWFNGLDWQAIFHQ 288
L +D +KR+G + G +K+H +F + W+ + Q
Sbjct: 355 LVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 391
>U08438-1|AAB60689.1| 689|Homo sapiens beta-adrenergic receptor
kinase protein.
Length = 689
Score = 199 bits (485), Expect = 1e-50
Identities = 106/288 (36%), Positives = 172/288 (59%), Gaps = 12/288 (4%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DF + + IG G +GEV+ R + T +AMK ++K + + + L L ++I+ +
Sbjct: 187 TMNDFSVHRIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSL 245
Query: 79 ----QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILAL 134
PF+V + AF L FIL + GG++ ++ ++G+FS++ +FYA+++IL L
Sbjct: 246 VSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGL 305
Query: 135 EYLHYCEVVHRDIKPENILIDSNGYLKLCDFGF-CKVLKKKTWTLCGTPEYLAPEVITSK 193
E++H VV+RD+KP NIL+D +G++++ D G C KKK GT Y+APEV+ K
Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVL-QK 364
Query: 194 G--YSFSVDWWALGDLSFEMEAGHPPF---FASDPNKLYEKVLVGSYKCPENMSPECKNL 248
G Y S DW++LG + F++ GH PF D +++ L + + P++ SPE +L
Sbjct: 365 GVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELHSL 424
Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296
L+GLLQ D ++R+G L G E+K +F LDWQ +F QK P +P
Sbjct: 425 LEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIP 472
>M80776-1|AAA58391.1| 689|Homo sapiens receptor kinase protein.
Length = 689
Score = 199 bits (485), Expect = 1e-50
Identities = 106/288 (36%), Positives = 172/288 (59%), Gaps = 12/288 (4%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DF + + IG G +GEV+ R T +AMK ++K + + + L L ++I+ +
Sbjct: 187 TMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSL 245
Query: 79 ----QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILAL 134
PF+V + AF L FIL + GG++ ++ ++G+FS++ +FYA+++IL L
Sbjct: 246 VSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGL 305
Query: 135 EYLHYCEVVHRDIKPENILIDSNGYLKLCDFGF-CKVLKKKTWTLCGTPEYLAPEVITSK 193
E++H VV+RD+KP NIL+D +G++++ D G C KKK GT Y+APEV+ K
Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVL-QK 364
Query: 194 G--YSFSVDWWALGDLSFEMEAGHPPF---FASDPNKLYEKVLVGSYKCPENMSPECKNL 248
G Y S DW++LG + F++ GH PF D +++ L + + P++ SPE ++L
Sbjct: 365 GVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSL 424
Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296
L+GLLQ D ++R+G L G E+K +F LDWQ +F QK P +P
Sbjct: 425 LEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIP 472
>BC090863-1|AAH90863.1| 689|Homo sapiens ADRBK1 protein protein.
Length = 689
Score = 199 bits (485), Expect = 1e-50
Identities = 106/288 (36%), Positives = 172/288 (59%), Gaps = 12/288 (4%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DF + + IG G +GEV+ R T +AMK ++K + + + L L ++I+ +
Sbjct: 187 TMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSL 245
Query: 79 ----QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILAL 134
PF+V + AF L FIL + GG++ ++ ++G+FS++ +FYA+++IL L
Sbjct: 246 VSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGL 305
Query: 135 EYLHYCEVVHRDIKPENILIDSNGYLKLCDFGF-CKVLKKKTWTLCGTPEYLAPEVITSK 193
E++H VV+RD+KP NIL+D +G++++ D G C KKK GT Y+APEV+ K
Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVL-QK 364
Query: 194 G--YSFSVDWWALGDLSFEMEAGHPPF---FASDPNKLYEKVLVGSYKCPENMSPECKNL 248
G Y S DW++LG + F++ GH PF D +++ L + + P++ SPE ++L
Sbjct: 365 GVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSL 424
Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296
L+GLLQ D ++R+G L G E+K +F LDWQ +F QK P +P
Sbjct: 425 LEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIP 472
>BC037963-1|AAH37963.1| 689|Homo sapiens adrenergic, beta, receptor
kinase 1 protein.
Length = 689
Score = 199 bits (485), Expect = 1e-50
Identities = 106/288 (36%), Positives = 172/288 (59%), Gaps = 12/288 (4%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DF + + IG G +GEV+ R T +AMK ++K + + + L L ++I+ +
Sbjct: 187 TMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSL 245
Query: 79 ----QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILAL 134
PF+V + AF L FIL + GG++ ++ ++G+FS++ +FYA+++IL L
Sbjct: 246 VSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGL 305
Query: 135 EYLHYCEVVHRDIKPENILIDSNGYLKLCDFGF-CKVLKKKTWTLCGTPEYLAPEVITSK 193
E++H VV+RD+KP NIL+D +G++++ D G C KKK GT Y+APEV+ K
Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVL-QK 364
Query: 194 G--YSFSVDWWALGDLSFEMEAGHPPF---FASDPNKLYEKVLVGSYKCPENMSPECKNL 248
G Y S DW++LG + F++ GH PF D +++ L + + P++ SPE ++L
Sbjct: 365 GVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSL 424
Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296
L+GLLQ D ++R+G L G E+K +F LDWQ +F QK P +P
Sbjct: 425 LEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIP 472
>X61157-1|CAA43470.1| 689|Homo sapiens beta-adrenergic receptor
kinase protein.
Length = 689
Score = 198 bits (482), Expect = 3e-50
Identities = 105/288 (36%), Positives = 172/288 (59%), Gaps = 12/288 (4%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DF + + IG G +GEV+ R + T +AMK ++K + + + L L ++I+ +
Sbjct: 187 TMNDFSVHRIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSL 245
Query: 79 ----QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILAL 134
PF+V + AF L FIL + GG++ ++ ++G+FS++ +FYA+++IL L
Sbjct: 246 VSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGL 305
Query: 135 EYLHYCEVVHRDIKPENILIDSNGYLKLCDFGF-CKVLKKKTWTLCGTPEYLAPEVITSK 193
E++H VV+RD+KP NIL+D +G++++ D G C KKK GT Y+APEV+ K
Sbjct: 306 EHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVL-QK 364
Query: 194 G--YSFSVDWWALGDLSFEMEAGHPPF---FASDPNKLYEKVLVGSYKCPENMSPECKNL 248
G Y S DW++LG + F++ GH PF D +++ L + + P++ SPE +L
Sbjct: 365 GVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELHSL 424
Query: 249 LKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVP 296
L+GLLQ D ++R+G L G E+K +F LDWQ +F Q+ P +P
Sbjct: 425 LEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQRYPPPLIP 472
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 197 bits (481), Expect = 4e-50
Identities = 94/277 (33%), Positives = 166/277 (59%), Gaps = 6/277 (2%)
Query: 18 KTVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQC 77
K +DF K +G G++ V L R+ T +A+K++EK +++ N ++ E+ ++
Sbjct: 77 KRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSR 136
Query: 78 IQFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYL 137
+ PF V L F+D+ LYF L Y GE+ YI+K G F ++ T+FY ++++ A EYL
Sbjct: 137 LDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSASEYL 196
Query: 138 HYCEVVHRDIKPENILIDSNGYLKLCDFGFCKVL-----KKKTWTLCGTPEYLAPEVITS 192
H ++HRD+KPENIL++ + ++++ DFG KVL + + + GT +Y++PE++T
Sbjct: 197 HGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTE 256
Query: 193 KGYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVLVGSYKCPENMSPECKNLLKGL 252
K S D WALG + +++ AG PPF A + +++K++ Y PE P+ ++L++ L
Sbjct: 257 KSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKL 316
Query: 253 LQVDPSKRIGSLK-GGIYEIKSHTWFNGLDWQAIFHQ 288
L +D +KR+G + G +K+H +F + W+ + Q
Sbjct: 317 LVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQ 353
>DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein
kinase beta (DMPK-like) protein.
Length = 1711
Score = 193 bits (471), Expect = 6e-49
Identities = 103/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K T +AMK++ K +++R E+ +L
Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ L AF+D +LY ++ Y GG++ T + K+ + + +FY +++LA++ +H
Sbjct: 134 QWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQ 193
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITSK-- 193
VHRDIKP+N+L+D NG+++L DFG C + ++ GTP+Y++PE++ +
Sbjct: 194 LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMED 253
Query: 194 ---GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPE---NMSPEC 245
Y DWW+LG +EM G PF+A + Y K++ ++ P ++S E
Sbjct: 254 GMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEA 313
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ +R+G + GI + K H +F GL+W+ I + L AP++P SSP DTS
Sbjct: 314 KDLIQRLI-CSRERRLG--QNGIEDFKKHAFFEGLNWENI--RNLEAPYIPDVSSPSDTS 368
Query: 306 NF 307
NF
Sbjct: 369 NF 370
>BC048261-1|AAH48261.1| 492|Homo sapiens CDC42BPB protein protein.
Length = 492
Score = 193 bits (471), Expect = 6e-49
Identities = 103/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K T +AMK++ K +++R E+ +L
Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ L AF+D +LY ++ Y GG++ T + K+ + + +FY +++LA++ +H
Sbjct: 134 QWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQ 193
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITSK-- 193
VHRDIKP+N+L+D NG+++L DFG C + ++ GTP+Y++PE++ +
Sbjct: 194 LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMED 253
Query: 194 ---GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPE---NMSPEC 245
Y DWW+LG +EM G PF+A + Y K++ ++ P ++S E
Sbjct: 254 GMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEA 313
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ +R+G + GI + K H +F GL+W+ I + L AP++P SSP DTS
Sbjct: 314 KDLIQRLI-CSRERRLG--QNGIEDFKKHAFFEGLNWENI--RNLEAPYIPDVSSPSDTS 368
Query: 306 NF 307
NF
Sbjct: 369 NF 370
>BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein.
Length = 933
Score = 193 bits (471), Expect = 6e-49
Identities = 103/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K T +AMK++ K +++R E+ +L
Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ L AF+D +LY ++ Y GG++ T + K+ + + +FY +++LA++ +H
Sbjct: 134 QWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQ 193
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITSK-- 193
VHRDIKP+N+L+D NG+++L DFG C + ++ GTP+Y++PE++ +
Sbjct: 194 LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMED 253
Query: 194 ---GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPE---NMSPEC 245
Y DWW+LG +EM G PF+A + Y K++ ++ P ++S E
Sbjct: 254 GMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEA 313
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ +R+G + GI + K H +F GL+W+ I + L AP++P SSP DTS
Sbjct: 314 KDLIQRLI-CSRERRLG--QNGIEDFKKHAFFEGLNWENI--RNLEAPYIPDVSSPSDTS 368
Query: 306 NF 307
NF
Sbjct: 369 NF 370
>AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein
kinase beta protein.
Length = 1711
Score = 193 bits (471), Expect = 6e-49
Identities = 103/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K T +AMK++ K +++R E+ +L
Sbjct: 74 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 133
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ L AF+D +LY ++ Y GG++ T + K+ + + +FY +++LA++ +H
Sbjct: 134 QWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQ 193
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITSK-- 193
VHRDIKP+N+L+D NG+++L DFG C + ++ GTP+Y++PE++ +
Sbjct: 194 LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMED 253
Query: 194 ---GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPE---NMSPEC 245
Y DWW+LG +EM G PF+A + Y K++ ++ P ++S E
Sbjct: 254 GMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEA 313
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ +R+G + GI + K H +F GL+W+ I + L AP++P SSP DTS
Sbjct: 314 KDLIQRLI-CSRERRLG--QNGIEDFKKHAFFEGLNWENI--RNLEAPYIPDVSSPSDTS 368
Query: 306 NF 307
NF
Sbjct: 369 NF 370
>AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein.
Length = 1760
Score = 193 bits (471), Expect = 6e-49
Identities = 103/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K T +AMK++ K +++R E+ +L
Sbjct: 123 EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDC 182
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ L AF+D +LY ++ Y GG++ T + K+ + + +FY +++LA++ +H
Sbjct: 183 QWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQ 242
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITSK-- 193
VHRDIKP+N+L+D NG+++L DFG C + ++ GTP+Y++PE++ +
Sbjct: 243 LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMED 302
Query: 194 ---GYSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCPE---NMSPEC 245
Y DWW+LG +EM G PF+A + Y K++ ++ P ++S E
Sbjct: 303 GMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEA 362
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ +R+G + GI + K H +F GL+W+ I + L AP++P SSP DTS
Sbjct: 363 KDLIQRLI-CSRERRLG--QNGIEDFKKHAFFEGLNWENI--RNLEAPYIPDVSSPSDTS 417
Query: 306 NF 307
NF
Sbjct: 418 NF 419
>BC032709-1|AAH32709.1| 344|Homo sapiens Unknown (protein for
IMAGE:5496641) protein.
Length = 344
Score = 192 bits (468), Expect = 1e-48
Identities = 83/196 (42%), Positives = 132/196 (67%), Gaps = 3/196 (1%)
Query: 19 TVDDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCI 78
T++DFD +K +G G +G+V LVR+K T Y+AMK++ K V++ ++ H + E ++LQ
Sbjct: 148 TMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNT 207
Query: 79 QFPFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYGIFSDSLTKFYASQVILALEYLH 138
+ PF+ L AF+ + L F++ Y GGE+F ++ + +F++ +FY ++++ ALEYLH
Sbjct: 208 RHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLH 267
Query: 139 YCEVVHRDIKPENILIDSNGYLKLCDFGFCK--VLKKKTW-TLCGTPEYLAPEVITSKGY 195
+VV+RDIK EN+++D +G++K+ DFG CK + T T CGTPEYLAPEV+ Y
Sbjct: 268 SRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDY 327
Query: 196 SFSVDWWALGDLSFEM 211
+VDWW LG + +EM
Sbjct: 328 GRAVDWWGLGVVMYEM 343
>U59305-1|AAB37126.1| 496|Homo sapiens ser-thr protein kinase PK428
protein.
Length = 496
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AL627308-4|CAH71338.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AL451047-2|CAH71184.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AL353689-8|CAI19110.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AJ518976-1|CAD57746.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 75 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 134
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 254
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 255 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 314
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 315 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 369
Query: 306 NF 307
NF
Sbjct: 370 NF 371
>AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein
kinase alpha variant protein.
Length = 1702
Score = 186 bits (454), Expect = 7e-47
Identities = 104/302 (34%), Positives = 175/302 (57%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
+DF+I+K IG GA+GEV +V+ K AMK++ K +++R E+ +L
Sbjct: 86 EDFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN 145
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
++ TL AF+D+ LY ++ Y GG++ T + K+ + + +FY +++++A++ +H
Sbjct: 146 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 205
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITS--- 192
VHRDIKP+NIL+D NG+++L DFG C L + ++ GTP+Y++PE++ +
Sbjct: 206 LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMED 265
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG +EM G PF+A + Y K++ ++ P ++S
Sbjct: 266 GKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENA 325
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
K+L++ L+ R+G + GI + K H +F+G+DW I + AP++P SSP DTS
Sbjct: 326 KDLIRRLI-CSREHRLG--QNGIEDFKKHPFFSGIDWDNI--RNCEAPYIPEVSSPTDTS 380
Query: 306 NF 307
NF
Sbjct: 381 NF 382
>AY648038-1|AAT67172.1| 1551|Homo sapiens myotonic dystrophy
kinase-related CDC42-binding kinase gamma protein.
Length = 1551
Score = 184 bits (449), Expect = 3e-46
Identities = 103/302 (34%), Positives = 172/302 (56%), Gaps = 20/302 (6%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
DDF+I+K IG GA+GEV +VR + T AMK++ K +++R E+ +L
Sbjct: 69 DDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREERDVLVKGDS 128
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKY-GIFSDSLTKFYASQVILALEYLHY 139
+V TL AF+D YLY ++ Y AGG++ T + ++ L +FY ++++LA+ LH
Sbjct: 129 RWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMVLAIHSLHQ 188
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKKK----TWTLCGTPEYLAPEVITS--- 192
VHRD+KP+N+L+D NG+++L DFG C L + GTP+Y++PE++ +
Sbjct: 189 LGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISPEILQAMEE 248
Query: 193 -KG-YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL--VGSYKCP---ENMSPEC 245
KG Y DWW+LG ++E+ G PF+A + Y K++ + P ++
Sbjct: 249 GKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPDVPDVPASA 308
Query: 246 KNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGDTS 305
++L++ LL +R+G +GG+ + ++H +F G+DW+ + AP++P P DTS
Sbjct: 309 QDLIRQLL-CRQEERLG--RGGLDDFRNHPFFEGVDWERL--ASSTAPYIPELRGPMDTS 363
Query: 306 NF 307
NF
Sbjct: 364 NF 365
>S72883-1|AAB31800.1| 625|Homo sapiens myotonin protein kinase
protein.
Length = 625
Score = 184 bits (447), Expect = 5e-46
Identities = 101/304 (33%), Positives = 167/304 (54%), Gaps = 22/304 (7%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
DDF+I+K IG GA+ EV +V+ K T +AMK++ K +++R E+ +L
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYG-IFSDSLTKFYASQVILALEYLHY 139
++ L AF+D YLY ++ Y GG++ T + K+G + +FY +++++A++ +H
Sbjct: 129 RWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHR 188
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITSKG- 194
VHRDIKP+NIL+D G+++L DFG C L+ ++ GTP+YL+PE++ + G
Sbjct: 189 LGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGG 248
Query: 195 ------YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL-----VGSYKCPENMSP 243
Y DWWALG ++EM G PF+A + Y K++ + E +
Sbjct: 249 GPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPE 308
Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303
E ++ ++ LL P R+G +GG + ++H +F GLDW + + + PF P D
Sbjct: 309 EARDFIQRLL-CPPETRLG--RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTPDFEGATD 363
Query: 304 TSNF 307
T NF
Sbjct: 364 TCNF 367
>M94203-1|AAA64884.1| 582|Homo sapiens protein kinase protein.
Length = 582
Score = 184 bits (447), Expect = 5e-46
Identities = 101/304 (33%), Positives = 167/304 (54%), Gaps = 22/304 (7%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
DDF+I+K IG GA+ EV +V+ K T +AMK++ K +++R E+ +L
Sbjct: 28 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 87
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYG-IFSDSLTKFYASQVILALEYLHY 139
++ L AF+D YLY ++ Y GG++ T + K+G + +FY +++++A++ +H
Sbjct: 88 RWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHR 147
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITSKG- 194
VHRDIKP+NIL+D G+++L DFG C L+ ++ GTP+YL+PE++ + G
Sbjct: 148 LGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGG 207
Query: 195 ------YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL-----VGSYKCPENMSP 243
Y DWWALG ++EM G PF+A + Y K++ + E +
Sbjct: 208 GPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPE 267
Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303
E ++ ++ LL P R+G +GG + ++H +F GLDW + + + PF P D
Sbjct: 268 EARDFIQRLL-CPPETRLG--RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTPDFEGATD 322
Query: 304 TSNF 307
T NF
Sbjct: 323 TCNF 326
>L19268-1|AAA36206.1| 624|Homo sapiens protein kinase protein.
Length = 624
Score = 184 bits (447), Expect = 5e-46
Identities = 101/304 (33%), Positives = 167/304 (54%), Gaps = 22/304 (7%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
DDF+I+K IG GA+ EV +V+ K T +AMK++ K +++R E+ +L
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYG-IFSDSLTKFYASQVILALEYLHY 139
++ L AF+D YLY ++ Y GG++ T + K+G + +FY +++++A++ +H
Sbjct: 129 RWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHR 188
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITSKG- 194
VHRDIKP+NIL+D G+++L DFG C L+ ++ GTP+YL+PE++ + G
Sbjct: 189 LGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGG 248
Query: 195 ------YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL-----VGSYKCPENMSP 243
Y DWWALG ++EM G PF+A + Y K++ + E +
Sbjct: 249 GPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPE 308
Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303
E ++ ++ LL P R+G +GG + ++H +F GLDW + + + PF P D
Sbjct: 309 EARDFIQRLL-CPPETRLG--RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTPDFEGATD 363
Query: 304 TSNF 307
T NF
Sbjct: 364 TCNF 367
>L08835-5|AAC14450.1| 530|Homo sapiens myotonic dystrophy kinase
protein.
Length = 530
Score = 184 bits (447), Expect = 5e-46
Identities = 101/304 (33%), Positives = 167/304 (54%), Gaps = 22/304 (7%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
DDF+I+K IG GA+ EV +V+ K T +AMK++ K +++R E+ +L
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYG-IFSDSLTKFYASQVILALEYLHY 139
++ L AF+D YLY ++ Y GG++ T + K+G + +FY +++++A++ +H
Sbjct: 129 RWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHR 188
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITSKG- 194
VHRDIKP+NIL+D G+++L DFG C L+ ++ GTP+YL+PE++ + G
Sbjct: 189 LGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGG 248
Query: 195 ------YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL-----VGSYKCPENMSP 243
Y DWWALG ++EM G PF+A + Y K++ + E +
Sbjct: 249 GPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPE 308
Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303
E ++ ++ LL P R+G +GG + ++H +F GLDW + + + PF P D
Sbjct: 309 EARDFIQRLL-CPPETRLG--RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTPDFEGATD 363
Query: 304 TSNF 307
T NF
Sbjct: 364 TCNF 367
>L08835-4|AAC14451.1| 535|Homo sapiens myotonic dystrophy kinase
protein.
Length = 535
Score = 184 bits (447), Expect = 5e-46
Identities = 101/304 (33%), Positives = 167/304 (54%), Gaps = 22/304 (7%)
Query: 21 DDFDIVKAIGNGAYGEVFLVRDKITFTYHAMKVVEKSVVVERNHAKHLILEKKILQCIQF 80
DDF+I+K IG GA+ EV +V+ K T +AMK++ K +++R E+ +L
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDR 128
Query: 81 PFVVTLDVAFKDNLYLYFILPYIAGGEMFTYIQKYG-IFSDSLTKFYASQVILALEYLHY 139
++ L AF+D YLY ++ Y GG++ T + K+G + +FY +++++A++ +H
Sbjct: 129 RWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHR 188
Query: 140 CEVVHRDIKPENILIDSNGYLKLCDFGFCKVLKK----KTWTLCGTPEYLAPEVITSKG- 194
VHRDIKP+NIL+D G+++L DFG C L+ ++ GTP+YL+PE++ + G
Sbjct: 189 LGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGG 248
Query: 195 ------YSFSVDWWALGDLSFEMEAGHPPFFASDPNKLYEKVL-----VGSYKCPENMSP 243
Y DWWALG ++EM G PF+A + Y K++ + E +
Sbjct: 249 GPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPE 308
Query: 244 ECKNLLKGLLQVDPSKRIGSLKGGIYEIKSHTWFNGLDWQAIFHQKLIAPFVPICSSPGD 303
E ++ ++ LL P R+G +GG + ++H +F GLDW + + + PF P D
Sbjct: 309 EARDFIQRLL-CPPETRLG--RGGAGDFRTHPFFFGLDWDGL--RDSVPPFTPDFEGATD 363
Query: 304 TSNF 307
T NF
Sbjct: 364 TCNF 367
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.141 0.439
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 53,351,411
Number of Sequences: 224733
Number of extensions: 2347655
Number of successful extensions: 10865
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2553
Number of HSP's successfully gapped in prelim test: 240
Number of HSP's that attempted gapping in prelim test: 3702
Number of HSP's gapped (non-prelim): 3350
length of query: 330
length of database: 73,234,838
effective HSP length: 90
effective length of query: 240
effective length of database: 53,008,868
effective search space: 12722128320
effective search space used: 12722128320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 65 (30.3 bits)
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