Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000974-TA|BGIBMGA000974-PA|IPR001245|Tyrosine protein
kinase, IPR008266|Tyrosine protein kinase, active site,
IPR000719|Protein kinase, IPR011009|Protein kinase-like
(153 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; E... 282 3e-75
UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86; Coel... 204 5e-52
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 203 1e-51
UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ... 198 6e-50
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 195 3e-49
UniRef50_UPI00004D86FC Cluster: Tyrosine-protein kinase Tec (EC ... 194 9e-49
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 191 7e-48
UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX... 187 8e-47
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 181 5e-45
UniRef50_Q9I9L1 Cluster: Arg protein-tyrosine kinase; n=12; Tetr... 181 7e-45
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 180 2e-44
UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1... 178 4e-44
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 177 9e-44
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 177 9e-44
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 177 9e-44
UniRef50_UPI0000ECD739 Cluster: Cytoplasmic tyrosine-protein kin... 177 1e-43
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92... 175 3e-43
UniRef50_Q4S351 Cluster: Chromosome 4 SCAF14752, whole genome sh... 175 3e-43
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 173 1e-42
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 173 1e-42
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 173 2e-42
UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32; Eute... 171 7e-42
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 170 1e-41
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 168 4e-41
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 168 4e-41
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol... 168 5e-41
UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g... 167 7e-41
UniRef50_Q9TX48 Cluster: 220 kDa ABL-related protein tyrosine ki... 165 3e-40
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 165 4e-40
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 163 1e-39
UniRef50_Q910A2 Cluster: Spleen protein tyrosine kinase; n=2; Da... 163 1e-39
UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol... 162 3e-39
UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m... 162 3e-39
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 160 1e-38
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 160 1e-38
UniRef50_P04629 Cluster: High affinity nerve growth factor recep... 160 1e-38
UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular ... 159 2e-38
UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Re... 159 3e-38
UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole... 158 6e-38
UniRef50_Q2VXS7 Cluster: Proto-oncogene c-fes variant 4; n=77; E... 157 7e-38
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 157 1e-37
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 156 2e-37
UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine prot... 156 2e-37
UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gamb... 155 3e-37
UniRef50_UPI00015A7C25 Cluster: UPI00015A7C25 related cluster; n... 155 4e-37
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 155 4e-37
UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p... 155 5e-37
UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine prot... 155 5e-37
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 155 5e-37
UniRef50_Q70W05 Cluster: Src protein; n=1; Ciona intestinalis|Re... 154 7e-37
UniRef50_Q05397 Cluster: Focal adhesion kinase 1; n=111; Euteleo... 154 7e-37
UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En... 154 9e-37
UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel... 154 9e-37
UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man... 153 1e-36
UniRef50_Q4SQ93 Cluster: Tyrosine-protein kinase receptor; n=2; ... 152 3e-36
UniRef50_Q9Y1Y3 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 152 3e-36
UniRef50_Q91987 Cluster: BDNF/NT-3 growth factors receptor precu... 152 3e-36
UniRef50_Q16620 Cluster: BDNF/NT-3 growth factors receptor precu... 152 4e-36
UniRef50_UPI00015A61DF Cluster: UPI00015A61DF related cluster; n... 151 6e-36
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 150 1e-35
UniRef50_A7SI92 Cluster: Predicted protein; n=2; Nematostella ve... 150 1e-35
UniRef50_P08923 Cluster: Leukocyte tyrosine kinase receptor prec... 150 1e-35
UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,... 150 1e-35
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 150 1e-35
UniRef50_A6P4V4 Cluster: Tyrosine-protein kinase receptor; n=2; ... 150 1e-35
UniRef50_Q9UM73 Cluster: ALK tyrosine kinase receptor precursor;... 150 1e-35
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 149 2e-35
UniRef50_Q5TUS8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 149 2e-35
UniRef50_O76148 Cluster: Tyrosine-protein kinase receptor; n=1; ... 149 2e-35
UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;... 149 3e-35
UniRef50_Q4RY69 Cluster: Chromosome 3 SCAF14978, whole genome sh... 149 3e-35
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1... 149 3e-35
UniRef50_UPI0000E47C0F Cluster: PREDICTED: similar to focal adhe... 149 3e-35
UniRef50_Q7Z1D3 Cluster: Focal adhesion kinase; n=1; Lytechinus ... 149 3e-35
UniRef50_Q5MCM8 Cluster: Protein-tyrosine kinase; n=2; Anthomedu... 149 3e-35
UniRef50_UPI00015B5971 Cluster: PREDICTED: similar to leukocyte ... 148 5e-35
UniRef50_UPI0000D569CE Cluster: PREDICTED: similar to CG10023-PA... 148 5e-35
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 148 5e-35
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 148 6e-35
UniRef50_Q7KJ08 Cluster: Receptor protein tyrosine kinase ALK sp... 148 6e-35
UniRef50_Q14289 Cluster: Protein tyrosine kinase 2 beta; n=47; E... 148 6e-35
UniRef50_UPI0000DB6D22 Cluster: PREDICTED: similar to Alk CG8250... 147 8e-35
UniRef50_Q4SK07 Cluster: Tyrosine-protein kinase receptor; n=2; ... 147 8e-35
UniRef50_Q17C76 Cluster: Focal adhesion kinase; n=2; Culicidae|R... 147 8e-35
UniRef50_Q8JFV0 Cluster: Tyrosine-protein kinase receptor; n=5; ... 147 1e-34
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 147 1e-34
UniRef50_A6NNJ8 Cluster: Uncharacterized protein LTK; n=12; Euar... 147 1e-34
UniRef50_Q98TD0 Cluster: Ephrin receptor; n=6; Amniota|Rep: Ephr... 146 1e-34
UniRef50_Q19238 Cluster: Putative tyrosine-protein kinase F09A5.... 146 1e-34
UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther... 146 1e-34
UniRef50_UPI0000D57520 Cluster: PREDICTED: similar to CG8250-PA;... 146 2e-34
UniRef50_Q9U531 Cluster: Focal adhesion kinase homolog DFak56; n... 146 2e-34
UniRef50_Q7YT64 Cluster: Tyrosine-protein kinase receptor; n=1; ... 146 2e-34
UniRef50_Q12866 Cluster: Proto-oncogene tyrosine-protein kinase ... 146 2e-34
UniRef50_Q9VBW3 Cluster: Tyrosine kinase receptor Cad96Ca precur... 146 2e-34
UniRef50_Q9XVQ7 Cluster: Putative uncharacterized protein; n=2; ... 145 3e-34
UniRef50_Q52V39 Cluster: Tyrosine-protein kinase receptor; n=2; ... 145 3e-34
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 145 3e-34
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 145 3e-34
UniRef50_UPI0000E257E1 Cluster: PREDICTED: similar to tyrosine k... 145 4e-34
UniRef50_Q4RJ67 Cluster: Chromosome 1 SCAF15039, whole genome sh... 145 4e-34
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 145 4e-34
UniRef50_Q8IXC7 Cluster: Isoform of FGFR2; n=23; Euteleostomi|Re... 145 4e-34
UniRef50_Q4SQX3 Cluster: Chromosome 11 SCAF14528, whole genome s... 144 6e-34
UniRef50_Q25410 Cluster: Putative molluscan insulin-related pept... 144 6e-34
UniRef50_Q16288 Cluster: NT-3 growth factor receptor precursor; ... 144 7e-34
UniRef50_Q3TJ05 Cluster: 14 days pregnant adult female placenta ... 144 1e-33
UniRef50_Q9VZI2 Cluster: CG14992-PA; n=3; Sophophora|Rep: CG1499... 144 1e-33
UniRef50_Q96HF4 Cluster: EPHA2 protein; n=3; Amniota|Rep: EPHA2 ... 144 1e-33
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd... 144 1e-33
UniRef50_P29317 Cluster: Ephrin type-A receptor 2 precursor; n=3... 144 1e-33
UniRef50_UPI0000F2052A Cluster: PREDICTED: similar to anaplastic... 143 1e-33
UniRef50_Q9BKL8 Cluster: Tyrosine-protein kinase receptor; n=2; ... 143 1e-33
UniRef50_P11362 Cluster: Basic fibroblast growth factor receptor... 143 1e-33
UniRef50_O76997 Cluster: Putative neurotrophin receptor LTRK 1 p... 143 2e-33
UniRef50_Q6DTW4 Cluster: Tyrosine kinase receptor ron; n=6; Eume... 142 2e-33
UniRef50_Q170Z1 Cluster: Tyrosine-protein kinase receptor; n=1; ... 142 2e-33
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 142 2e-33
UniRef50_O17391 Cluster: Protein kinase protein 9, isoform b; n=... 142 2e-33
UniRef50_P08922 Cluster: Proto-oncogene tyrosine-protein kinase ... 142 2e-33
UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12; E... 142 2e-33
UniRef50_UPI00015B4CAE Cluster: PREDICTED: similar to ENSANGP000... 142 3e-33
UniRef50_UPI0000E4736E Cluster: PREDICTED: similar to src-family... 142 3e-33
UniRef50_Q9U8U9 Cluster: PDGFR-like; n=1; Eptatretus burgeri|Rep... 142 3e-33
UniRef50_Q7Q5T3 Cluster: Tyrosine-protein kinase receptor; n=3; ... 142 3e-33
UniRef50_A7RGW8 Cluster: Predicted protein; n=1; Nematostella ve... 142 3e-33
UniRef50_Q59F30 Cluster: Fibroblast growth factor receptor 4 var... 142 3e-33
UniRef50_Q06418 Cluster: Tyrosine-protein kinase receptor TYRO3 ... 142 4e-33
UniRef50_P79950 Cluster: Tyrosine kinase receptor; n=3; Xenopus|... 141 5e-33
UniRef50_Q008W6 Cluster: Gamma-carboxyglutamic acid protein 1; n... 141 5e-33
UniRef50_P29322 Cluster: Ephrin type-A receptor 8 precursor; n=2... 141 5e-33
UniRef50_Q9YI66 Cluster: Developmental receptor tyrosine kinase;... 141 7e-33
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 141 7e-33
UniRef50_Q17LF1 Cluster: Muscle-specific tyrosine kinase recepto... 141 7e-33
UniRef50_P30530 Cluster: Tyrosine-protein kinase receptor UFO pr... 141 7e-33
UniRef50_Q04912 Cluster: Macrophage-stimulating protein receptor... 141 7e-33
UniRef50_O02742 Cluster: Activated CDC42 kinase 2; n=13; Euteleo... 141 7e-33
UniRef50_Q07912 Cluster: Activated CDC42 kinase 1; n=24; Euteleo... 141 7e-33
UniRef50_UPI0000E49FB6 Cluster: PREDICTED: similar to RE05926p, ... 140 9e-33
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 140 9e-33
UniRef50_Q9Y1Y9 Cluster: Protein tyrosine kinase; n=3; Metazoa|R... 140 9e-33
UniRef50_Q4H2M8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 140 9e-33
UniRef50_O16131 Cluster: Insulin receptor homolog precursor; n=2... 140 9e-33
UniRef50_A7RVU0 Cluster: Predicted protein; n=1; Nematostella ve... 140 9e-33
UniRef50_Q02763 Cluster: Angiopoietin-1 receptor precursor; n=41... 140 9e-33
UniRef50_UPI0000D57494 Cluster: PREDICTED: similar to insulin re... 140 1e-32
UniRef50_Q9Y1Y5 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 140 1e-32
UniRef50_Q9U5A8 Cluster: Insulin receptor-like protein precursor... 140 1e-32
UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E... 140 1e-32
UniRef50_Q24488 Cluster: Tyrosine-protein kinase transmembrane r... 140 1e-32
UniRef50_Q03142 Cluster: Fibroblast growth factor receptor 4 pre... 140 1e-32
UniRef50_P22182 Cluster: Fibroblast growth factor receptor 1 pre... 140 1e-32
UniRef50_UPI0000E471D0 Cluster: PREDICTED: similar to p80 protei... 140 2e-32
UniRef50_Q4SR43 Cluster: Chromosome 11 SCAF14528, whole genome s... 140 2e-32
UniRef50_Q4RWP2 Cluster: Tyrosine-protein kinase receptor; n=1; ... 140 2e-32
UniRef50_Q9Y1Y6 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 140 2e-32
UniRef50_P35590 Cluster: Tyrosine-protein kinase receptor Tie-1 ... 140 2e-32
UniRef50_P08069 Cluster: Insulin-like growth factor 1 receptor p... 140 2e-32
UniRef50_Q8JG38 Cluster: Fibroblast growth factor receptor 2 pre... 140 2e-32
UniRef50_P21709 Cluster: Ephrin type-A receptor 1 precursor; n=1... 140 2e-32
UniRef50_UPI00004D7E5F Cluster: Proto-oncogene tyrosine-protein ... 139 3e-32
UniRef50_A7SAX2 Cluster: Predicted protein; n=3; Nematostella ve... 139 3e-32
UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18; Eu... 138 4e-32
UniRef50_P23049 Cluster: Tyrosine-protein kinase transforming pr... 138 4e-32
UniRef50_P00529 Cluster: Tyrosine-protein kinase transforming pr... 138 4e-32
UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precurso... 138 4e-32
UniRef50_O02466 Cluster: Insulin-like peptide receptor precursor... 138 4e-32
UniRef50_Q4S1S8 Cluster: Chromosome undetermined SCAF14764, whol... 138 5e-32
UniRef50_Q7Q0F6 Cluster: Tyrosine-protein kinase receptor; n=2; ... 138 5e-32
UniRef50_Q5DM52 Cluster: Receptor tyrosine kinase Torso-like pro... 138 5e-32
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 138 5e-32
UniRef50_Q01973 Cluster: Tyrosine-protein kinase transmembrane r... 138 5e-32
UniRef50_P16234 Cluster: Alpha-type platelet-derived growth fact... 138 5e-32
UniRef50_UPI000065F647 Cluster: Ephrin type-B receptor 2 precurs... 138 6e-32
UniRef50_Q64GK4 Cluster: C-Met receptor tyrosine kinase; n=9; Cl... 138 6e-32
UniRef50_Q9Y1Y8 Cluster: Protein tyrosine kinase; n=2; Metazoa|R... 138 6e-32
UniRef50_Q93105 Cluster: Insulin-like receptor precursor (EC 2.7... 138 6e-32
UniRef50_O73798 Cluster: Insulin-like growth factor 1 receptor p... 138 6e-32
UniRef50_A2CG59 Cluster: Eph receptor B1; n=23; Euteleostomi|Rep... 137 9e-32
UniRef50_Q9V4E5 Cluster: CG1511-PC, isoform C; n=12; Diptera|Rep... 137 9e-32
UniRef50_Q7PYY7 Cluster: ENSANGP00000019144; n=1; Anopheles gamb... 137 9e-32
UniRef50_Q7PWP1 Cluster: ENSANGP00000013218; n=2; Culicidae|Rep:... 137 9e-32
UniRef50_A7SL46 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 137 9e-32
UniRef50_P18475 Cluster: Tyrosine-protein kinase receptor torso ... 137 9e-32
UniRef50_P29323 Cluster: Ephrin type-B receptor 2 precursor; n=3... 137 9e-32
UniRef50_UPI0000D55449 Cluster: PREDICTED: similar to CG7223-PA,... 137 1e-31
UniRef50_Q6PFV6 Cluster: Ephrin receptor; n=11; Tetrapoda|Rep: E... 137 1e-31
UniRef50_UPI000065E56D Cluster: EPHB1_HUMAN Isoform 3 of P54762 ... 136 1e-31
UniRef50_P54756 Cluster: Ephrin type-A receptor 5 precursor; n=1... 136 1e-31
UniRef50_UPI00015B54DC Cluster: PREDICTED: similar to vascular e... 136 2e-31
UniRef50_UPI0000D57178 Cluster: PREDICTED: similar to CG14396-PA... 136 2e-31
UniRef50_Q8T0W6 Cluster: Putative insulin receptor precursor; n=... 136 2e-31
UniRef50_O76385 Cluster: Putative uncharacterized protein; n=3; ... 136 2e-31
UniRef50_UPI0000DB7F8D Cluster: PREDICTED: similar to Cad96Ca CG... 136 3e-31
UniRef50_UPI000065FEDC Cluster: Activated CDC42 kinase 1 (EC 2.7... 135 3e-31
UniRef50_Q9YGM5 Cluster: Plasminogen related growth factor recep... 135 3e-31
UniRef50_Q5IJ68 Cluster: Trk-like receptor tyrosine kinase; n=1;... 135 3e-31
UniRef50_UPI00006A1E7A Cluster: Non-receptor tyrosine-protein ki... 135 5e-31
UniRef50_Q4RXA0 Cluster: Chromosome 11 SCAF14979, whole genome s... 135 5e-31
UniRef50_Q9Y1X8 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 135 5e-31
UniRef50_Q6VU50 Cluster: Eph receptor; n=3; Endopterygota|Rep: E... 135 5e-31
UniRef50_Q6TYB9 Cluster: Dauer abnormal formation-2 precursor; n... 135 5e-31
UniRef50_Q2LC18 Cluster: Tyrosine-protein kinase receptor; n=2; ... 135 5e-31
UniRef50_Q9V6K3 Cluster: Tyrosine-protein kinase transmembrane r... 135 5e-31
UniRef50_UPI0000DB6B52 Cluster: PREDICTED: similar to Ror CG4926... 134 6e-31
UniRef50_Q9UF33 Cluster: Ephrin type-A receptor 6 precursor; n=5... 134 6e-31
UniRef50_UPI000069DB6A Cluster: Ephrin type-A receptor 6 precurs... 134 8e-31
UniRef50_Q10656-2 Cluster: Isoform b of Q10656 ; n=4; Caenorhabd... 134 8e-31
UniRef50_Q4SC90 Cluster: Chromosome undetermined SCAF14659, whol... 134 8e-31
UniRef50_Q4JDD5 Cluster: Tyrosine-protein kinase receptor; n=5; ... 134 8e-31
UniRef50_Q1JUB8 Cluster: Fibroblast growth factor receptor; n=2;... 134 8e-31
UniRef50_Q17J18 Cluster: Tyrosine-protein kinase; n=4; Endoptery... 134 8e-31
UniRef50_Q10656 Cluster: Myoblast growth factor receptor egl-15 ... 134 8e-31
UniRef50_A7RZ71 Cluster: Predicted protein; n=1; Nematostella ve... 134 1e-30
UniRef50_A3EXK4 Cluster: Fibroblast growth factor receptor a; n=... 134 1e-30
UniRef50_Q07407 Cluster: Fibroblast growth factor receptor homol... 134 1e-30
UniRef50_Q15375 Cluster: Ephrin type-A receptor 7 precursor; n=5... 134 1e-30
UniRef50_Q10925-2 Cluster: Isoform b of Q10925 ; n=2; Caenorhabd... 133 1e-30
UniRef50_Q4SFK0 Cluster: Chromosome 7 SCAF14601, whole genome sh... 133 1e-30
UniRef50_Q4SFJ9 Cluster: Chromosome 7 SCAF14601, whole genome sh... 133 1e-30
UniRef50_Q9Y1Z4 Cluster: Protein tyrosine kinase 37; n=1; Hydra ... 133 1e-30
UniRef50_Q9VLQ8 Cluster: CG8222-PA, isoform A; n=8; Sophophora|R... 133 1e-30
UniRef50_Q8T4M0 Cluster: VEGFR-A splice form A; n=4; Diptera|Rep... 133 1e-30
UniRef50_Q7YZH7 Cluster: MBRTK2; n=1; Monosiga brevicollis|Rep: ... 133 1e-30
UniRef50_Q5D184 Cluster: Ephrin receptor; n=2; Apocrita|Rep: Eph... 133 1e-30
UniRef50_O45232 Cluster: Putative uncharacterized protein ark-1;... 133 1e-30
UniRef50_P08581 Cluster: Hepatocyte growth factor receptor precu... 133 1e-30
UniRef50_Q10925 Cluster: Probable tyrosine-protein kinase kin-25... 133 1e-30
UniRef50_UPI000065E2FA Cluster: Homolog of Homo sapiens "Tyrosin... 133 2e-30
UniRef50_Q9Y1Y0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 133 2e-30
UniRef50_Q8IQ00 Cluster: CG3277-PB, isoform B; n=3; Sophophora|R... 133 2e-30
UniRef50_Q7YZW6 Cluster: Putative uncharacterized protein; n=3; ... 133 2e-30
UniRef50_Q7PT15 Cluster: ENSANGP00000009263; n=2; Culicidae|Rep:... 133 2e-30
UniRef50_Q4H3M3 Cluster: Ephrin receptor like protein; n=1; Cion... 133 2e-30
UniRef50_O97191 Cluster: Tyrosine-protein kinase receptor; n=1; ... 133 2e-30
UniRef50_P17948 Cluster: Vascular endothelial growth factor rece... 133 2e-30
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 133 2e-30
UniRef50_P79749 Cluster: Beta-type platelet-derived growth facto... 133 2e-30
UniRef50_Q9PVZ4 Cluster: Insulin receptor precursor (EC 2.7.10.1... 133 2e-30
UniRef50_P09208 Cluster: Insulin-like receptor precursor (EC 2.7... 133 2e-30
UniRef50_P14616 Cluster: Insulin receptor-related protein precur... 133 2e-30
UniRef50_UPI0000E47549 Cluster: PREDICTED: similar to Cek8; n=2;... 132 2e-30
UniRef50_Q8INU0 Cluster: CG14396-PD, isoform D; n=10; Sophophora... 132 2e-30
UniRef50_A7RHT9 Cluster: Predicted protein; n=1; Nematostella ve... 132 2e-30
UniRef50_UPI00015B5959 Cluster: PREDICTED: similar to insulin re... 132 3e-30
UniRef50_Q4SMF1 Cluster: Chromosome 8 SCAF14552, whole genome sh... 132 3e-30
UniRef50_Q9BLY1 Cluster: Receptor tyrosine kinase; n=5; Caenorha... 132 3e-30
UniRef50_Q16UV1 Cluster: Protein kinase protein; n=3; Culicidae|... 132 3e-30
UniRef50_A7SFD8 Cluster: Predicted protein; n=2; Nematostella ve... 132 3e-30
UniRef50_A3EXK5 Cluster: Fibroblast growth factor receptor b; n=... 132 3e-30
UniRef50_Q8MY86 Cluster: Fibroblast growth factor receptor 1 pre... 132 3e-30
UniRef50_Q5K4G5 Cluster: Receptor tyrosine kinase; n=1; Suberite... 132 4e-30
UniRef50_Q8AXB3 Cluster: Vascular endothelial growth factor rece... 132 4e-30
UniRef50_UPI0000DB6C99 Cluster: PREDICTED: similar to proto-onco... 131 6e-30
UniRef50_UPI0000660568 Cluster: Ephrin type-B receptor 2 precurs... 131 6e-30
UniRef50_Q4S1M5 Cluster: Chromosome 6 SCAF14768, whole genome sh... 131 6e-30
UniRef50_A7RNB1 Cluster: Predicted protein; n=1; Nematostella ve... 131 6e-30
UniRef50_Q4SWL0 Cluster: Ephrin receptor; n=3; Tetraodontidae|Re... 131 7e-30
UniRef50_Q4SF69 Cluster: Chromosome undetermined SCAF14608, whol... 131 7e-30
UniRef50_Q9U8U8 Cluster: VEGFR-like; n=1; Branchiostoma belcheri... 131 7e-30
UniRef50_Q7Q0U2 Cluster: ENSANGP00000012311; n=1; Anopheles gamb... 131 7e-30
UniRef50_Q09147 Cluster: Fibroblast growth factor receptor homol... 131 7e-30
UniRef50_UPI0000DB7A0A Cluster: PREDICTED: similar to FMS-like t... 130 1e-29
UniRef50_UPI0000DB6DD4 Cluster: PREDICTED: similar to Insulin-li... 130 1e-29
UniRef50_Q4RXB0 Cluster: Chromosome 11 SCAF14979, whole genome s... 130 1e-29
UniRef50_Q7Z1L9 Cluster: Neurite outgrowth regulated kinase; n=1... 130 1e-29
UniRef50_Q4H3M5 Cluster: Ephrin receptor; n=1; Ciona intestinali... 130 1e-29
UniRef50_Q4H3M4 Cluster: Ephrin receptor; n=2; Ciona intestinali... 130 1e-29
UniRef50_A7S934 Cluster: Predicted protein; n=4; Nematostella ve... 130 1e-29
UniRef50_P13368 Cluster: Protein sevenless; n=20; Eumetazoa|Rep:... 130 1e-29
UniRef50_Q4TFI7 Cluster: Chromosome undetermined SCAF4439, whole... 130 1e-29
UniRef50_Q4SP88 Cluster: Ephrin receptor; n=2; Tetraodon nigrovi... 130 1e-29
UniRef50_Q8WRF4 Cluster: Receptor tyrosine kinase; n=1; Monosiga... 130 1e-29
UniRef50_Q7YXV8 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 130 1e-29
UniRef50_Q15303 Cluster: Receptor tyrosine-protein kinase erbB-4... 130 1e-29
UniRef50_Q9Y1Y7 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 130 2e-29
UniRef50_Q7YSY1 Cluster: Fes-like tyrosine kinase protein; n=1; ... 130 2e-29
UniRef50_Q4H3B8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 130 2e-29
UniRef50_Q179Z3 Cluster: Tyrosine-protein kinase; n=1; Aedes aeg... 130 2e-29
UniRef50_P09619 Cluster: Beta-type platelet-derived growth facto... 130 2e-29
UniRef50_P06213 Cluster: Insulin receptor precursor (EC 2.7.10.1... 130 2e-29
UniRef50_UPI0000D55DFF Cluster: PREDICTED: similar to Insulin-li... 129 2e-29
UniRef50_UPI000051AB92 Cluster: PREDICTED: similar to Fak-like t... 129 2e-29
UniRef50_Q4SJQ3 Cluster: Tyrosine-protein kinase receptor; n=1; ... 129 2e-29
UniRef50_Q70W11 Cluster: Receptor tyrosine kinase X; n=1; Ciona ... 129 2e-29
UniRef50_Q0IFX6 Cluster: Pdgf/vegf receptor; n=1; Aedes aegypti|... 129 2e-29
UniRef50_A7RGV3 Cluster: Predicted protein; n=1; Nematostella ve... 129 2e-29
UniRef50_UPI00015B51DA Cluster: PREDICTED: similar to ENSANGP000... 129 3e-29
UniRef50_Q95ZV7 Cluster: Putative uncharacterized protein; n=3; ... 129 3e-29
UniRef50_Q16RK6 Cluster: Receptor protein tyrosine kinase; n=1; ... 129 3e-29
UniRef50_UPI0000D56EE8 Cluster: PREDICTED: similar to CG14992-PA... 128 4e-29
UniRef50_Q5I4E2 Cluster: Bm-DAF-2 precursor; n=1; Brugia malayi|... 128 4e-29
UniRef50_Q4H3N2 Cluster: Epidermal growth factor receptor; n=1; ... 128 4e-29
UniRef50_Q17IF1 Cluster: Receptor protein tyrosine kinase; n=1; ... 128 4e-29
UniRef50_O76411 Cluster: Suppressor of constitutive dauer format... 128 4e-29
UniRef50_UPI00015B5A01 Cluster: PREDICTED: similar to protein ki... 128 5e-29
UniRef50_Q1HTP2 Cluster: Tyrosine-protein kinase receptor; n=4; ... 128 5e-29
UniRef50_Q01974 Cluster: Tyrosine-protein kinase transmembrane r... 128 5e-29
UniRef50_Q6Q8C0 Cluster: Tec protein tyrosine kinase; n=3; Eutel... 128 7e-29
UniRef50_O76809 Cluster: Receptor tyrosine kinase HTK30; n=1; Hy... 128 7e-29
UniRef50_UPI00015B4221 Cluster: PREDICTED: similar to tyrosine-p... 127 9e-29
UniRef50_Q4SMB8 Cluster: Chromosome 3 SCAF14553, whole genome sh... 127 9e-29
UniRef50_Q95YD4 Cluster: Protein kinase protein 32, isoform a; n... 127 9e-29
UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty... 127 9e-29
UniRef50_Q25177 Cluster: Receptor protein-tyrosine kinase; n=2; ... 127 9e-29
UniRef50_Q27324 Cluster: Tyrosine-protein kinase Drl precursor; ... 127 9e-29
UniRef50_UPI00015B4DC3 Cluster: PREDICTED: similar to receptor t... 127 1e-28
UniRef50_UPI0000E47068 Cluster: PREDICTED: similar to tyrosine p... 127 1e-28
UniRef50_Q4T272 Cluster: Chromosome undetermined SCAF10323, whol... 127 1e-28
UniRef50_A0JMM7 Cluster: Zgc:154019; n=2; Danio rerio|Rep: Zgc:1... 127 1e-28
UniRef50_A7SP77 Cluster: Predicted protein; n=1; Nematostella ve... 127 1e-28
UniRef50_Q95YM9 Cluster: Fibroblast growth factor receptor precu... 127 1e-28
UniRef50_Q674V1 Cluster: Vascular endothelial growth factor rece... 126 2e-28
UniRef50_Q25199 Cluster: Tyrosine kinase receptor; n=7; Hydra|Re... 126 2e-28
UniRef50_Q25197 Cluster: Putative insulin-like peptide receptor ... 126 2e-28
UniRef50_Q26614 Cluster: Fibroblast growth factor receptor precu... 126 2e-28
UniRef50_P07333 Cluster: Macrophage colony-stimulating factor 1 ... 126 2e-28
UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; ... 126 2e-28
UniRef50_Q70W12 Cluster: Discoidin receptor; n=1; Ciona intestin... 126 2e-28
UniRef50_Q4H3M7 Cluster: Ephrin receptor; n=3; Ciona|Rep: Ephrin... 126 2e-28
UniRef50_P35968 Cluster: Vascular endothelial growth factor rece... 126 2e-28
UniRef50_A7RWY4 Cluster: Predicted protein; n=1; Nematostella ve... 126 3e-28
UniRef50_Q8JFR5 Cluster: Mast/stem cell growth factor receptor p... 126 3e-28
UniRef50_UPI0000F1F8B4 Cluster: PREDICTED: hypothetical protein;... 125 4e-28
UniRef50_UPI000065F6B2 Cluster: Receptor tyrosine-protein kinase... 125 4e-28
UniRef50_Q9Y1X7 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 125 4e-28
UniRef50_Q6SAJ2 Cluster: Epidermal growth factor receptor; n=11;... 125 4e-28
UniRef50_Q6SAA3 Cluster: Epidermal growth factor receptor; n=39;... 125 4e-28
UniRef50_Q17JW1 Cluster: Tyrosine protein kinase; n=2; Culicidae... 125 4e-28
UniRef50_P04412 Cluster: Epidermal growth factor receptor precur... 125 4e-28
UniRef50_UPI0000E48069 Cluster: PREDICTED: hypothetical protein;... 125 5e-28
UniRef50_UPI0000DB7330 Cluster: PREDICTED: similar to Ack CG1499... 125 5e-28
UniRef50_Q640T5 Cluster: Tyrosine-protein kinase receptor; n=2; ... 124 6e-28
UniRef50_A7SZN9 Cluster: Predicted protein; n=3; Nematostella ve... 124 6e-28
UniRef50_UPI0000D563AD Cluster: PREDICTED: similar to CG3969-PA,... 124 8e-28
UniRef50_Q1HTP1 Cluster: Tyrosine-protein kinase receptor; n=1; ... 124 8e-28
UniRef50_A3EXK6 Cluster: Fibroblast growth factor receptor c; n=... 124 8e-28
UniRef50_Q4RV12 Cluster: Ephrin receptor; n=2; Tetraodontidae|Re... 124 1e-27
UniRef50_Q86MD7 Cluster: EGF receptor; n=1; Echinococcus multilo... 124 1e-27
UniRef50_P04626 Cluster: Receptor tyrosine-protein kinase erbB-2... 124 1e-27
UniRef50_UPI0000E47617 Cluster: PREDICTED: similar to muscle spe... 123 1e-27
UniRef50_Q86PM4 Cluster: Fibroblast growth factor receptor precu... 123 1e-27
UniRef50_Q08345 Cluster: Epithelial discoidin domain-containing ... 123 1e-27
UniRef50_A7RL50 Cluster: Predicted protein; n=1; Nematostella ve... 122 3e-27
UniRef50_P36888 Cluster: FL cytokine receptor precursor; n=33; A... 122 3e-27
UniRef50_Q8UVR8 Cluster: Macrophage colony-stimulating factor 1 ... 122 3e-27
UniRef50_UPI0000D5603D Cluster: PREDICTED: similar to Insulin re... 122 3e-27
UniRef50_P35916 Cluster: Vascular endothelial growth factor rece... 122 3e-27
UniRef50_P42687 Cluster: Tyrosine-protein kinase SPK-1; n=1; Gir... 122 3e-27
UniRef50_UPI0000D8BE91 Cluster: UPI0000D8BE91 related cluster; n... 122 5e-27
UniRef50_UPI00015B5C00 Cluster: PREDICTED: similar to VEGFR-A sp... 121 6e-27
UniRef50_UPI0000DB7735 Cluster: PREDICTED: similar to Insulin re... 121 6e-27
UniRef50_Q4RH14 Cluster: Chromosome undetermined SCAF15074, whol... 121 6e-27
UniRef50_Q4L0H7 Cluster: Insulin receptor tyrosine kinase; n=2; ... 121 6e-27
UniRef50_Q21041 Cluster: Putative uncharacterized protein ver-4;... 121 6e-27
UniRef50_A7S4Y9 Cluster: Predicted protein; n=1; Nematostella ve... 121 6e-27
UniRef50_Q16832 Cluster: Discoidin domain-containing receptor 2 ... 121 8e-27
UniRef50_Q17PG3 Cluster: Tyrosine-protein kinase drl; n=5; Endop... 120 1e-26
UniRef50_Q2VJ45 Cluster: HOOK3-RET fusion protein; n=3; Eutheria... 120 1e-26
UniRef50_P07949 Cluster: Proto-oncogene tyrosine-protein kinase ... 120 1e-26
UniRef50_UPI00015B55E4 Cluster: PREDICTED: similar to receptor-l... 120 1e-26
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 120 1e-26
UniRef50_Q9XYS4 Cluster: Tyrosine kinase receptor HTK32; n=1; Hy... 120 1e-26
UniRef50_P21860 Cluster: Receptor tyrosine-protein kinase erbB-3... 120 1e-26
UniRef50_Q9I8N6 Cluster: Macrophage colony-stimulating factor 1 ... 120 1e-26
UniRef50_UPI0000F202EE Cluster: PREDICTED: similar to LCK2; n=2;... 120 2e-26
UniRef50_UPI0000D576E5 Cluster: PREDICTED: similar to CG33531-PA... 120 2e-26
UniRef50_P34925 Cluster: Tyrosine-protein kinase RYK precursor; ... 120 2e-26
UniRef50_UPI00006A26D5 Cluster: UPI00006A26D5 related cluster; n... 119 2e-26
UniRef50_Q5BXN9 Cluster: SJCHGC05493 protein; n=1; Schistosoma j... 119 2e-26
UniRef50_Q21038 Cluster: Putative uncharacterized protein ver-3;... 119 2e-26
UniRef50_Q24592 Cluster: Tyrosine-protein kinase hopscotch; n=2;... 119 2e-26
UniRef50_Q5JZY3 Cluster: Ephrin type-A receptor 10 precursor; n=... 119 2e-26
UniRef50_UPI0000DB72A0 Cluster: PREDICTED: similar to R151.4a; n... 119 3e-26
UniRef50_UPI00015B6067 Cluster: PREDICTED: similar to tyrosine p... 118 4e-26
UniRef50_Q70W09 Cluster: Receptor tyrosine kinase VIII; n=1; Cio... 118 6e-26
UniRef50_Q5GIT4 Cluster: Vascular endothelial growth factor rece... 118 6e-26
UniRef50_P10721 Cluster: Mast/stem cell growth factor receptor p... 118 6e-26
UniRef50_Q4RQ50 Cluster: Chromosome 17 SCAF15006, whole genome s... 117 1e-25
UniRef50_Q9V422 Cluster: Tyrosine-protein kinase Dnt precursor; ... 117 1e-25
UniRef50_P34891 Cluster: Receptor-like tyrosine-protein kinase k... 117 1e-25
UniRef50_Q86LZ8 Cluster: Insulin receptor protein kinase; n=2; S... 117 1e-25
UniRef50_P00534 Cluster: Tyrosine-protein kinase transforming pr... 117 1e-25
UniRef50_UPI0000E470E3 Cluster: PREDICTED: similar to Fer, parti... 116 2e-25
UniRef50_UPI00015A58A4 Cluster: UPI00015A58A4 related cluster; n... 116 2e-25
UniRef50_A7RX97 Cluster: Predicted protein; n=1; Nematostella ve... 116 2e-25
UniRef50_O61460 Cluster: Ephrin receptor 1 precursor; n=3; Caeno... 116 2e-25
UniRef50_P34892 Cluster: Receptor-like tyrosine-protein kinase k... 116 2e-25
UniRef50_A1IKE0 Cluster: Receptor tyrosine kinase-like orphan re... 116 2e-25
UniRef50_O12990 Cluster: Tyrosine-protein kinase Jak1; n=8; Eute... 116 2e-25
UniRef50_Q8MY85 Cluster: Fibroblast growth factor receptor 2 pre... 116 2e-25
UniRef50_Q26566 Cluster: Epidermal growth factor receptor precur... 115 4e-25
UniRef50_Q25198 Cluster: Receptor tyrosine kinase 90; n=1; Hydra... 115 4e-25
UniRef50_P00533 Cluster: Epidermal growth factor receptor precur... 115 5e-25
UniRef50_UPI0000E48358 Cluster: PREDICTED: hypothetical protein;... 114 9e-25
UniRef50_Q5RIU8 Cluster: Novel protein similar to vertebrate dis... 114 9e-25
UniRef50_UPI00005A2D48 Cluster: PREDICTED: similar to EPH recept... 113 1e-24
UniRef50_UPI00015B4A8D Cluster: PREDICTED: similar to receptor t... 113 2e-24
UniRef50_Q0P4R9 Cluster: Discoidin domain receptor family, membe... 113 2e-24
UniRef50_Q4H3N3 Cluster: Epidermal growth factor receptor; n=1; ... 113 2e-24
UniRef50_Q03351 Cluster: NT-3 growth factor receptor precursor; ... 112 4e-24
UniRef50_UPI00015B629F Cluster: PREDICTED: similar to CG33531-PA... 111 5e-24
UniRef50_Q9GRH2 Cluster: Tyrosine-protein kinase receptor; n=1; ... 111 5e-24
UniRef50_P24348 Cluster: Receptor tyrosine-protein kinase let-23... 111 5e-24
UniRef50_Q4RPK6 Cluster: Chromosome 12 SCAF15007, whole genome s... 111 8e-24
UniRef50_Q7YZH5 Cluster: MBTK3; n=1; Monosiga brevicollis|Rep: M... 111 8e-24
UniRef50_Q13470 Cluster: Non-receptor tyrosine-protein kinase TN... 111 8e-24
UniRef50_A7SE14 Cluster: Predicted protein; n=4; Nematostella ve... 110 1e-23
UniRef50_UPI0000D56AE3 Cluster: PREDICTED: similar to CG1594-PA;... 110 1e-23
UniRef50_Q4SUM3 Cluster: Ephrin receptor; n=4; Tetraodon nigrovi... 110 1e-23
UniRef50_Q22489 Cluster: Putative uncharacterized protein; n=4; ... 110 1e-23
UniRef50_Q4RXV8 Cluster: Chromosome 11 SCAF14979, whole genome s... 109 2e-23
UniRef50_P52333 Cluster: Tyrosine-protein kinase JAK3; n=17; Eut... 109 2e-23
UniRef50_UPI0001556099 Cluster: PREDICTED: similar to PTK7 prote... 109 3e-23
UniRef50_UPI0000D55A9B Cluster: PREDICTED: similar to CG8789-PA,... 109 3e-23
UniRef50_Q4RQT4 Cluster: Chromosome 2 SCAF15004, whole genome sh... 109 3e-23
UniRef50_A7RNB2 Cluster: Predicted protein; n=1; Nematostella ve... 109 3e-23
UniRef50_Q23554 Cluster: Putative uncharacterized protein; n=1; ... 109 3e-23
UniRef50_P79884 Cluster: Insulin-like growth factor-I receptor; ... 108 5e-23
UniRef50_UPI000155CF4D Cluster: PREDICTED: similar to EPH recept... 107 8e-23
UniRef50_Q9XZ66 Cluster: Tyrosine kinase receptor-related protei... 107 1e-22
UniRef50_Q8WSM2 Cluster: Receptor tyrosine kinase; n=1; Schistos... 107 1e-22
UniRef50_Q5G254 Cluster: Erbb3; n=6; Danio rerio|Rep: Erbb3 - Da... 107 1e-22
UniRef50_Q9Y1Y4 Cluster: Tyrosine-protein kinase; n=1; Ephydatia... 107 1e-22
UniRef50_Q5TRF2 Cluster: ENSANGP00000025511; n=1; Anopheles gamb... 107 1e-22
UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14... 107 1e-22
UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3; ... 106 2e-22
UniRef50_Q9GZG1 Cluster: Putative uncharacterized protein; n=6; ... 106 2e-22
UniRef50_Q61B52 Cluster: Putative uncharacterized protein CBG134... 106 2e-22
UniRef50_Q52ZF0 Cluster: Receptor tyrosine kinase-like protein; ... 106 2e-22
UniRef50_Q0MQ66 Cluster: Putative uncharacterized protein; n=5; ... 106 2e-22
UniRef50_O02064 Cluster: Putative uncharacterized protein; n=1; ... 106 2e-22
UniRef50_UPI00015B629D Cluster: PREDICTED: similar to CG33531-PA... 106 2e-22
UniRef50_UPI000065F9C5 Cluster: Epithelial discoidin domain-cont... 106 2e-22
UniRef50_UPI0000DB7238 Cluster: PREDICTED: similar to Discoidin ... 105 3e-22
UniRef50_Q9N3S5 Cluster: Putative uncharacterized protein; n=4; ... 105 3e-22
UniRef50_Q16RU6 Cluster: Mitogen-activated protein kinase kinase... 105 3e-22
UniRef50_UPI00015B6363 Cluster: PREDICTED: similar to tyrosine p... 105 4e-22
UniRef50_UPI0000519EF1 Cluster: PREDICTED: similar to CG31640-PA... 105 4e-22
UniRef50_Q4SI07 Cluster: Ephrin receptor; n=8; Clupeocephala|Rep... 105 4e-22
UniRef50_Q4RM64 Cluster: Chromosome 10 SCAF15019, whole genome s... 105 6e-22
UniRef50_Q24327 Cluster: Gp160-Dtrk precursor; n=4; Sophophora|R... 105 6e-22
UniRef50_Q12852 Cluster: Mitogen-activated protein kinase kinase... 105 6e-22
UniRef50_UPI00006A1DD3 Cluster: UPI00006A1DD3 related cluster; n... 104 7e-22
UniRef50_UPI000065E468 Cluster: Homolog of Gallus gallus "Ephrin... 104 7e-22
UniRef50_Q4S5N1 Cluster: Chromosome 9 SCAF14729, whole genome sh... 104 7e-22
UniRef50_Q4RP85 Cluster: Tyrosine-protein kinase receptor; n=3; ... 104 7e-22
UniRef50_Q8I7I5 Cluster: Roller: helically twisted, animals roll... 104 7e-22
UniRef50_Q6SAX5 Cluster: Epidermal growth factor receptor; n=14;... 104 7e-22
UniRef50_A2FI59 Cluster: TKL family protein kinase; n=1; Trichom... 104 7e-22
UniRef50_UPI000065D1E0 Cluster: BDNF/NT-3 growth factors recepto... 104 1e-21
UniRef50_Q4RX00 Cluster: Chromosome 11 SCAF14979, whole genome s... 103 2e-21
UniRef50_Q012D5 Cluster: Tyrosine kinase specific for activated ... 103 2e-21
UniRef50_Q6J9G0 Cluster: Tyrosine protein-kinase STYK1; n=20; Am... 103 2e-21
UniRef50_UPI000049A16F Cluster: protein kinase; n=1; Entamoeba h... 103 2e-21
UniRef50_UPI0000DB7B4C Cluster: PREDICTED: similar to hopscotch ... 102 3e-21
UniRef50_Q17833 Cluster: Putative uncharacterized protein old-1;... 102 3e-21
UniRef50_Q15516 Cluster: Tyrosine kinase; n=1; Homo sapiens|Rep:... 102 3e-21
UniRef50_UPI00015B46B5 Cluster: PREDICTED: similar to CG33531-PA... 102 4e-21
UniRef50_P42159 Cluster: Class II receptor tyrosine kinase; n=5;... 102 4e-21
UniRef50_UPI0000DB74F2 Cluster: PREDICTED: similar to Derailed 2... 101 5e-21
UniRef50_UPI00006A0D3B Cluster: Tyrosine protein-kinase STYK1 (E... 101 5e-21
UniRef50_Q4RR57 Cluster: Chromosome 14 SCAF15003, whole genome s... 101 5e-21
UniRef50_Q259N0 Cluster: H0723C07.13 protein; n=4; Oryza sativa|... 101 7e-21
UniRef50_Q9GRH1 Cluster: Tyrosine-protein kinase receptor; n=4; ... 101 7e-21
UniRef50_Q7JQT0 Cluster: GH27039p; n=4; Diptera|Rep: GH27039p - ... 101 7e-21
UniRef50_UPI0000E49042 Cluster: PREDICTED: similar to RE05926p; ... 101 9e-21
UniRef50_Q6SAW1 Cluster: Epidermal growth factor receptor; n=70;... 101 9e-21
UniRef50_Q61BE2 Cluster: Putative uncharacterized protein CBG133... 101 9e-21
UniRef50_Q59DZ7 Cluster: CG33531-PA; n=6; Sophophora|Rep: CG3353... 101 9e-21
UniRef50_Q16VL6 Cluster: Tyrosine-protein kinase; n=1; Aedes aeg... 101 9e-21
UniRef50_Q10915 Cluster: Putative uncharacterized protein; n=2; ... 101 9e-21
UniRef50_O17408 Cluster: Putative uncharacterized protein; n=1; ... 101 9e-21
UniRef50_Q68KJ7 Cluster: HER2; n=3; Amniota|Rep: HER2 - Felis si... 100 1e-20
UniRef50_Q21868 Cluster: Putative uncharacterized protein; n=1; ... 100 1e-20
UniRef50_A2FCV2 Cluster: TKL family protein kinase; n=1; Trichom... 100 1e-20
UniRef50_UPI0000E47A46 Cluster: PREDICTED: similar to ret protei... 100 2e-20
UniRef50_A7R2R7 Cluster: Chromosome chr4 scaffold_443, whole gen... 100 2e-20
UniRef50_Q60WJ5 Cluster: Putative uncharacterized protein CBG191... 100 2e-20
UniRef50_Q9PWD1 Cluster: Tyrosine-protein kinase; n=3; Tetraodon... 99 2e-20
UniRef50_UPI00015B4B9F Cluster: PREDICTED: similar to prenylcyst... 100 3e-20
UniRef50_Q9Y1Z6 Cluster: Protein tyrosine kinase 13; n=1; Hydra ... 100 3e-20
UniRef50_UPI00015B628A Cluster: PREDICTED: similar to LD14856p; ... 99 4e-20
UniRef50_UPI0000DB7B8A Cluster: PREDICTED: similar to CG8789-PA,... 99 4e-20
UniRef50_UPI0000499A85 Cluster: protein kinase; n=1; Entamoeba h... 99 4e-20
UniRef50_Q9N4T2 Cluster: Putative uncharacterized protein Y50D4B... 99 4e-20
UniRef50_Q17HL3 Cluster: Discoidin domain receptor; n=3; Culicid... 99 4e-20
UniRef50_UPI0000D560EA Cluster: PREDICTED: similar to CG31127-PA... 99 5e-20
UniRef50_Q21867 Cluster: Putative uncharacterized protein; n=2; ... 99 5e-20
UniRef50_Q4RNL0 Cluster: Chromosome 21 SCAF15012, whole genome s... 98 6e-20
UniRef50_A5AKP8 Cluster: Putative uncharacterized protein; n=1; ... 98 6e-20
UniRef50_Q18865 Cluster: Putative uncharacterized protein; n=5; ... 98 6e-20
UniRef50_O43283 Cluster: Mitogen-activated protein kinase kinase... 98 6e-20
UniRef50_Q9TYX4 Cluster: Putative uncharacterized protein R11E3.... 98 8e-20
UniRef50_UPI000065F2B9 Cluster: Ephrin type-A receptor 8 precurs... 97 1e-19
UniRef50_Q4S6E0 Cluster: Chromosome 10 SCAF14728, whole genome s... 97 1e-19
UniRef50_Q23136 Cluster: Putative uncharacterized protein; n=2; ... 97 1e-19
UniRef50_Q9VW24 Cluster: CG8789-PA, isoform A; n=3; Diptera|Rep:... 97 1e-19
UniRef50_UPI0000F1D883 Cluster: PREDICTED: hypothetical protein;... 97 2e-19
UniRef50_UPI0000E49DC5 Cluster: PREDICTED: similar to angiopoiet... 97 2e-19
>UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10;
Endopterygota|Rep: Tyrosine-protein kinase Btk29A -
Drosophila melanogaster (Fruit fly)
Length = 786
Score = 282 bits (691), Expect = 3e-75
Identities = 122/150 (81%), Positives = 139/150 (92%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLERHNYIHRDLAARNCLVG ENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV
Sbjct: 635 MTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 694
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
LN+TRFSSKSDVWA+GVLMWE+FTCGK+PYGRL N+EVV++VQRG +LEKPK C EIY+
Sbjct: 695 LNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYD 754
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQSV 150
VM+ CW H PEERP+FRVL +QLA+++Q++
Sbjct: 755 VMKLCWSHGPEERPAFRVLMDQLALVAQTL 784
>UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86;
Coelomata|Rep: Tyrosine-protein kinase Tec - Homo
sapiens (Human)
Length = 631
Score = 204 bits (499), Expect = 5e-52
Identities = 92/139 (66%), Positives = 108/139 (77%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLER+++IHRDLAARNCLV + VVKV+DFG+ARYVLDDQYTSS G KFP+KW PPEV
Sbjct: 477 MEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEV 536
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
N++RFSSKSDVW+FGVLMWEVFT G++P+ + TN EVV V RG L +PK N +Y
Sbjct: 537 FNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYE 596
Query: 121 VMRACWGHTPEERPSFRVL 139
VM CW PE RPSF L
Sbjct: 597 VMLRCWQEKPEGRPSFEDL 615
>UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18;
Euteleostomi|Rep: Tyrosine-protein kinase ITK/TSK - Homo
sapiens (Human)
Length = 620
Score = 203 bits (496), Expect = 1e-51
Identities = 92/151 (60%), Positives = 114/151 (75%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MAYLE IHRDLAARNCLVG+ V+KV+DFG+ R+VLDDQYTSS GTKFP+KWA PEV
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEV 529
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+F+R+SSKSDVW+FGVLMWEVF+ GK+PY +NSEVV+ + G L KP+ +Y
Sbjct: 530 FSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQ 589
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQSVL 151
+M CW PE+RP+F L QLA I++S L
Sbjct: 590 IMNHCWKERPEDRPAFSRLLRQLAEIAESGL 620
>UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein;
n=1; Suberites domuncula|Rep: Bruton's tyrosine
kinase-like protein - Suberites domuncula (Sponge)
Length = 700
Score = 198 bits (482), Expect = 6e-50
Identities = 86/143 (60%), Positives = 109/143 (76%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE +IHRDLAARNCLVG+ NVVKVADFGLAR+V+DD+YT+S GTKFPIKWA PEV
Sbjct: 541 MKYLEESGFIHRDLAARNCLVGERNVVKVADFGLARFVVDDEYTASEGTKFPIKWAAPEV 600
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+ +FSSKSDVW+FG+L+WE++T GK PY TNS+V+D+V G L++PK C E+Y
Sbjct: 601 ITHAKFSSKSDVWSFGILLWELWTGGKTPYPTFTNSQVLDEVLMGYRLDRPKQCPPEVYA 660
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+M CW ++RP F+ L L
Sbjct: 661 LMGKCWLTNSDDRPQFKTLSSSL 683
>UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54;
Gnathostomata|Rep: Tyrosine-protein kinase BTK - Homo
sapiens (Human)
Length = 659
Score = 195 bits (476), Expect = 3e-49
Identities = 80/139 (57%), Positives = 110/139 (79%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE ++HRDLAARNCLV D+ VVKV+DFGL+RYVLDD+YTSS G+KFP++W+PPEV
Sbjct: 509 MEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEV 568
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L +++FSSKSD+WAFGVLMWE+++ GK+PY R TNSE + + +G L +P ++Y
Sbjct: 569 LMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYT 628
Query: 121 VMRACWGHTPEERPSFRVL 139
+M +CW +ERP+F++L
Sbjct: 629 IMYSCWHEKADERPTFKIL 647
>UniRef50_UPI00004D86FC Cluster: Tyrosine-protein kinase Tec (EC
2.7.10.2).; n=1; Xenopus tropicalis|Rep:
Tyrosine-protein kinase Tec (EC 2.7.10.2). - Xenopus
tropicalis
Length = 647
Score = 194 bits (472), Expect = 9e-49
Identities = 86/126 (68%), Positives = 104/126 (82%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M+YLE++N+IHRDLAARNCLV D VVKV+DFG+ RYVLDDQYTSS G KFP+KW+PPEV
Sbjct: 519 MSYLEQNNFIHRDLAARNCLVNDAGVVKVSDFGMTRYVLDDQYTSSCGAKFPVKWSPPEV 578
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
N++RFSSKSDVW+FGVLMWEVFT GK+P+ +N EVV+ V RG+ L +PK IY+
Sbjct: 579 FNYSRFSSKSDVWSFGVLMWEVFTEGKMPFESYSNVEVVEMVTRGERLYRPKLATKIIYS 638
Query: 121 VMRACW 126
VM ACW
Sbjct: 639 VMVACW 644
>UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine
protein kinase BTK; n=1; Danio rerio|Rep: PREDICTED:
similar to tyrosine protein kinase BTK - Danio rerio
Length = 596
Score = 191 bits (465), Expect = 7e-48
Identities = 78/139 (56%), Positives = 107/139 (76%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE + +IHRDLAARNCLV +KV DFGL+RYVLDD+YTSS G+KFP++W+PPEV
Sbjct: 444 MKYLEANQFIHRDLAARNCLVDSNGTIKVTDFGLSRYVLDDEYTSSVGSKFPVRWSPPEV 503
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + +FSSKSD+WAFGVLMWE++T G++PY R N+E+V+K+ G L +P+ ++
Sbjct: 504 LLYCKFSSKSDIWAFGVLMWEIYTQGRMPYDRWNNTEIVEKISAGHRLYRPQMANENVFA 563
Query: 121 VMRACWGHTPEERPSFRVL 139
+M +CW P+ERP+F+ L
Sbjct: 564 IMNSCWHERPDERPTFQEL 582
>UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX;
n=36; Euteleostomi|Rep: Cytoplasmic tyrosine-protein
kinase BMX - Homo sapiens (Human)
Length = 675
Score = 187 bits (456), Expect = 8e-47
Identities = 83/139 (59%), Positives = 105/139 (75%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MA+LE H +IHRDLAARNCLV + VKV+DFG+ RYVLDDQY SS GTKFP+KW+ PEV
Sbjct: 524 MAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEV 583
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
++ ++SSKSDVWAFG+LMWEVF+ GK PY NS+VV KV +G L +P + IY
Sbjct: 584 FHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQ 643
Query: 121 VMRACWGHTPEERPSFRVL 139
+M +CW PE+RP+F+ L
Sbjct: 644 IMYSCWHELPEKRPTFQQL 662
>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
melanogaster (Fruit fly)
Length = 1620
Score = 181 bits (441), Expect = 5e-45
Identities = 79/143 (55%), Positives = 102/143 (71%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M+YLE NYIHRDLAARNCLVGD +VKVADFGLAR + DD YT+ G KFPIKW PE
Sbjct: 480 MSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEG 539
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + +FS+KSDVWAFGVL+WE+ T G PY + ++V K+ +G +E+P GC E+Y+
Sbjct: 540 LAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYD 599
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+MR CW +RP+F+ + L
Sbjct: 600 LMRQCWQWDATDRPTFKSIHHAL 622
>UniRef50_Q9I9L1 Cluster: Arg protein-tyrosine kinase; n=12;
Tetrapoda|Rep: Arg protein-tyrosine kinase - Xenopus
laevis (African clawed frog)
Length = 721
Score = 181 bits (440), Expect = 7e-45
Identities = 79/136 (58%), Positives = 100/136 (73%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLER N+IHRDLAARNCLVG+ +VVKVADFGL+R + D YT+ G KFPIKW PE
Sbjct: 5 MEYLERKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPES 64
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + FS KSDVWAFGVL+WE+ T G PY + S+V D +++G +E+P+GC ++Y
Sbjct: 65 LAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYE 124
Query: 121 VMRACWGHTPEERPSF 136
+MRACW P +RPSF
Sbjct: 125 LMRACWQWNPSDRPSF 140
>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
sapiens (Human)
Length = 1182
Score = 180 bits (437), Expect = 2e-44
Identities = 78/136 (57%), Positives = 101/136 (74%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE+ N+IHRDLAARNCLVG+ +VVKVADFGL+R + D YT+ G KFPIKW PE
Sbjct: 397 MEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPES 456
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + FS KSDVWAFGVL+WE+ T G PY + S+V D +++G +E+P+GC ++Y
Sbjct: 457 LAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYE 516
Query: 121 VMRACWGHTPEERPSF 136
+MRACW +P +RPSF
Sbjct: 517 LMRACWKWSPADRPSF 532
>UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1;
Eptatretus burgeri|Rep: TEC family protein tyrosine
kinase - Eptatretus burgeri (Inshore hagfish)
Length = 636
Score = 178 bits (434), Expect = 4e-44
Identities = 79/141 (56%), Positives = 103/141 (73%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE ++++HRDLAAR+CLVG++ +KV+DFG+ARYVLDDQYT S G +FP+KW+PPEV
Sbjct: 485 MVYLESNSFLHRDLAARHCLVGEDFSIKVSDFGMARYVLDDQYTCSQGARFPVKWSPPEV 544
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+ RFSSKSDVW+FGV+MWEVF+ G +PY +N EVV+ V G L +P +Y
Sbjct: 545 FDRGRFSSKSDVWSFGVVMWEVFSEGTLPYDGWSNGEVVESVHAGYQLPQPTLAPTPVYT 604
Query: 121 VMRACWGHTPEERPSFRVLKE 141
+M CW PE+RP F L E
Sbjct: 605 IMCDCWQPDPEKRPYFMKLLE 625
>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=15; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Abelson murine leukemia virus
Length = 746
Score = 177 bits (431), Expect = 9e-44
Identities = 76/148 (51%), Positives = 104/148 (70%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE+ N+IHRDLAARNCLVG+ ++VKVADFGL+R + D YT+ G KFPIKW PE
Sbjct: 237 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPES 296
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + +FS KSDVWAFGVL+WE+ T G PY + S+V + +++ +E+P+GC ++Y
Sbjct: 297 LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYE 356
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQ 148
+MRACW P +RPSF + + + Q
Sbjct: 357 LMRACWQWNPSDRPSFAEIHQAFETMFQ 384
>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=57; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Feline sarcoma virus (strain
Hardy-Zuckerman 2)
Length = 439
Score = 177 bits (431), Expect = 9e-44
Identities = 75/136 (55%), Positives = 101/136 (74%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE+ N+IHRDLAARNCLVG+ ++VKVADFGL+R + D YT+ GTKFPIKW PE
Sbjct: 300 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGTKFPIKWTAPES 359
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + +FS KSDVWAFGVL+WE+ T G PY + S+V + +++ +E+P+GC ++Y
Sbjct: 360 LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYE 419
Query: 121 VMRACWGHTPEERPSF 136
+MRACW P +RP+F
Sbjct: 420 LMRACWQWNPSDRPAF 435
>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase
ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein
kinase ABL1 - Homo sapiens (Human)
Length = 1130
Score = 177 bits (431), Expect = 9e-44
Identities = 76/148 (51%), Positives = 104/148 (70%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE+ N+IHRDLAARNCLVG+ ++VKVADFGL+R + D YT+ G KFPIKW PE
Sbjct: 351 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPES 410
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + +FS KSDVWAFGVL+WE+ T G PY + S+V + +++ +E+P+GC ++Y
Sbjct: 411 LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYE 470
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQ 148
+MRACW P +RPSF + + + Q
Sbjct: 471 LMRACWQWNPSDRPSFAEIHQAFETMFQ 498
>UniRef50_UPI0000ECD739 Cluster: Cytoplasmic tyrosine-protein kinase
BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in
chromosome X protein) (Epithelial and endothelial
tyrosine kinase) (ETK) (NTK38).; n=2; Gallus gallus|Rep:
Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)
(Bone marrow tyrosine kinase gene in chromosome X
protein) (Epithelial and endothelial tyrosine kinase)
(ETK) (NTK38). - Gallus gallus
Length = 633
Score = 177 bits (430), Expect = 1e-43
Identities = 79/139 (56%), Positives = 100/139 (71%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MA+LE IHRDLAARNCLV VK++DFG+ +YVLDD Y SS GTKFP+KW+ PEV
Sbjct: 479 MAFLESCQLIHRDLAARNCLVDSNLTVKLSDFGMTKYVLDDLYVSSLGTKFPVKWSAPEV 538
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
++T+FSSKSDVWAFG+LMWEVFT GK PY N +V++KV +G L +P+ + Y
Sbjct: 539 FHYTKFSSKSDVWAFGILMWEVFTLGKQPYELYDNMQVIEKVSQGYRLYRPQLVSDITYQ 598
Query: 121 VMRACWGHTPEERPSFRVL 139
+M CW PE+RP+F L
Sbjct: 599 IMYNCWHELPEKRPAFHQL 617
>UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92124
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 510
Score = 175 bits (427), Expect = 3e-43
Identities = 74/143 (51%), Positives = 103/143 (72%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MAY+E+ NYIHRDL A N LV + + K+ADFGLAR + DDQYT+ G KFPIKW PE
Sbjct: 353 MAYIEKKNYIHRDLRAANVLVSEMLLCKIADFGLARVIEDDQYTAREGAKFPIKWTAPEA 412
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+N+ F+ KSD+W+FGVL++E+ T GK+PY ++NSEV+ VQRG + +P+ C E+Y
Sbjct: 413 INYGSFTIKSDMWSFGVLLYEIITYGKIPYPGMSNSEVMSSVQRGYRMPRPENCPVELYE 472
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+M CW + PE+RP+F ++ L
Sbjct: 473 IMTTCWKNKPEDRPTFDYIQSVL 495
>UniRef50_Q4S351 Cluster: Chromosome 4 SCAF14752, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 4 SCAF14752, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 810
Score = 175 bits (426), Expect = 3e-43
Identities = 73/148 (49%), Positives = 105/148 (70%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MAYLE N IHRDLAARNCLVGD N +K++DFG++R D Y+SSG + PIKW PE
Sbjct: 662 MAYLESKNCIHRDLAARNCLVGDNNALKISDFGMSRQEDDGIYSSSGLKQIPIKWTAPEA 721
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
LN+ R+SS+SDVW++G+L+WE F+ G PY +TN + ++V++G + P+ C +++Y
Sbjct: 722 LNYGRYSSESDVWSYGILLWETFSLGMCPYPGMTNQQAREQVEKGYRMACPQRCPDDVYK 781
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQ 148
VM+ CW + PE+RP F L+ LA + +
Sbjct: 782 VMQRCWQYNPEDRPKFSELQRDLAAVKK 809
>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1 - Nasonia
vitripennis
Length = 1522
Score = 173 bits (421), Expect = 1e-42
Identities = 74/143 (51%), Positives = 102/143 (71%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M+YLE N+IHRDLAARNCLVG+ ++VKVADFGLAR + DD YT+ G KFPIKW PE
Sbjct: 399 MSYLESRNFIHRDLAARNCLVGESHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEG 458
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + +FS+KSDVWAFG+L+WE+ T G PY + ++V +++G +E P GC ++Y
Sbjct: 459 LAYNKFSTKSDVWAFGILLWEIATYGMSPYPGVDLTDVYHMLEKGYRMECPPGCPPKVYE 518
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+MR CW + +RP+F+ + L
Sbjct: 519 LMRQCWQWSASDRPTFKEIHHSL 541
>UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5;
Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 -
Caenorhabditis elegans
Length = 1224
Score = 173 bits (421), Expect = 1e-42
Identities = 79/154 (51%), Positives = 104/154 (67%), Gaps = 1/154 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M+YLE ++IHRDLAARNCLV + N+VK+ADFGLAR++ +D YT+ G KFPIKW PE
Sbjct: 420 MSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFMKEDTYTAHAGAKFPIKWTAPEG 479
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L F FSSKSDVWAFGVL+WE+ T G PY + S V ++ G ++ P+GC +Y
Sbjct: 480 LAFNTFSSKSDVWAFGVLLWEIATYGMAPYPGVELSNVYGLLENGFRMDGPQGCPPSVYR 539
Query: 121 VMRACWGHTPEERPSFRVLKEQLA-VISQSVLAD 153
+M CW +P +RP FR + L +IS + L D
Sbjct: 540 LMLQCWNWSPSDRPRFRDIHFNLENLISSNSLND 573
>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Abl tyrosine kinase CG4032-PA - Apis
mellifera
Length = 1439
Score = 173 bits (420), Expect = 2e-42
Identities = 74/143 (51%), Positives = 102/143 (71%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M+YLE N+IHRDLAARNCLVG+ ++VKVADFGLAR + DD YT+ G KFPIKW PE
Sbjct: 398 MSYLESRNFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEG 457
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + +FS+KSDVWAFG+L+WE+ T G PY + ++V +++G +E P GC ++Y
Sbjct: 458 LAYNKFSTKSDVWAFGILLWEIATYGMSPYPGVDLTDVYHMLEKGYRMECPPGCPPKVYE 517
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+MR CW + +RP+F+ + L
Sbjct: 518 LMRQCWQWSAADRPTFKEIHHSL 540
>UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32;
Euteleostomi|Rep: Tyrosine-protein kinase HCK - Homo
sapiens (Human)
Length = 526
Score = 171 bits (415), Expect = 7e-42
Identities = 71/143 (49%), Positives = 101/143 (70%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MA++E+ NYIHRDL A N LV V K+ADFGLAR + D++YT+ G KFPIKW PE
Sbjct: 369 MAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEA 428
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+NF F+ KSDVW+FG+L+ E+ T G++PY ++N EV+ ++RG + +P+ C E+YN
Sbjct: 429 INFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYN 488
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+M CW + PEERP+F ++ L
Sbjct: 489 IMMRCWKNRPEERPTFEYIQSVL 511
>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase
FER; n=109; root|Rep: Proto-oncogene tyrosine-protein
kinase FER - Homo sapiens (Human)
Length = 822
Score = 170 bits (413), Expect = 1e-41
Identities = 72/150 (48%), Positives = 103/150 (68%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE N IHRDLAARNCLVG+ NV+K++DFG++R Y+SSG + PIKW PE
Sbjct: 672 MLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEA 731
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
LN+ R+SS+SDVW+FG+L+WE F+ G PY +TN + ++V+RG + P+ C +I
Sbjct: 732 LNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISK 791
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQSV 150
+M CW + PE RP F L+++L +I + +
Sbjct: 792 IMMKCWDYKPENRPKFSELQKELTIIKRKL 821
>UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase
LCK; n=11; Coelomata|Rep: Proto-oncogene
tyrosine-protein kinase LCK - Homo sapiens (Human)
Length = 516
Score = 168 bits (409), Expect = 4e-41
Identities = 71/143 (49%), Positives = 98/143 (68%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MA++E NYIHRDL A N LV D K+ADFGLAR + D++YT+ G KFPIKW PE
Sbjct: 359 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEA 418
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+N+ F+ KSDVW+FG+L+ E+ T G++PY +TN EV+ ++RG + +P C E+Y
Sbjct: 419 INYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQ 478
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+MR CW PE+RP+F L+ L
Sbjct: 479 LMRLCWKERPEDRPTFDYLRSVL 501
>UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17;
Amniota|Rep: Tyrosine-protein kinase Srms - Homo sapiens
(Human)
Length = 488
Score = 168 bits (409), Expect = 4e-41
Identities = 77/146 (52%), Positives = 97/146 (66%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M+YLE +HRDLAARN LV D KVADFGLAR + DD Y+ S +K P+KW PE
Sbjct: 338 MSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEA 397
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
N+ FS KSDVW+FGVL+ EVFT G+ PY +TN E + ++ RG L +P C E+Y
Sbjct: 398 ANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGYRLPRPAACPAEVYV 457
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVI 146
+M CW +PEERPSF L+E+L I
Sbjct: 458 LMLECWRSSPEERPSFATLREKLHAI 483
>UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whole
genome shotgun sequence; n=8; Euteleostomi|Rep:
Chromosome undetermined SCAF15024, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 511
Score = 168 bits (408), Expect = 5e-41
Identities = 70/143 (48%), Positives = 100/143 (69%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MAY+ER NYIHRDL A N LV + + K+ADFGLAR + DD+Y++ G KFPIKW PE
Sbjct: 354 MAYIERRNYIHRDLRAANVLVSECLLCKIADFGLARVIEDDEYSAREGAKFPIKWTAPEA 413
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+N+ F+ KSD+W+FGVL++E+ T GK+PY +T EV+ +QRG + +P C +E+Y+
Sbjct: 414 INYGSFTIKSDMWSFGVLLYEIITYGKIPYPGMTKGEVISSIQRGYRMPQPDSCPSELYH 473
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+M CW P+ RP+F ++ L
Sbjct: 474 MMLDCWKDKPDARPTFEYMQSVL 496
>UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa
group|Rep: Src family kinase - Asterina miniata (Bat
star) (Patiria miniata)
Length = 563
Score = 167 bits (407), Expect = 7e-41
Identities = 72/139 (51%), Positives = 100/139 (71%), Gaps = 1/139 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MAYLE ++HRDLAARN LVGD KVADFGL+R +++D+Y + G K PIKW PE
Sbjct: 410 MAYLESQRFVHRDLAARNILVGDLRNCKVADFGLSR-IIEDEYIAKEGAKMPIKWTAPEA 468
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+NF +F+ KSDVW+FG+L++EV T G+VPY + N EV+D+V RG + KP C +++Y+
Sbjct: 469 INFGKFTIKSDVWSFGILIYEVITKGRVPYPGMVNREVLDQVSRGYRMPKPPECPDQLYD 528
Query: 121 VMRACWGHTPEERPSFRVL 139
+ + CW PE+RP+F L
Sbjct: 529 ITKQCWDAVPEKRPTFEFL 547
>UniRef50_Q9TX48 Cluster: 220 kDa ABL-related protein tyrosine
kinase; n=3; Strongylocentrotus purpuratus|Rep: 220 kDa
ABL-related protein tyrosine kinase - Strongylocentrotus
purpuratus (Purple sea urchin)
Length = 200
Score = 165 bits (402), Expect = 3e-40
Identities = 70/143 (48%), Positives = 101/143 (70%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M+YLE++++IHRDLAARNCL+G+ +++KVADFGLAR V + YT+ G KFPIKW PE
Sbjct: 36 MSYLEKNSFIHRDLAARNCLLGEHHLLKVADFGLARMVQGEIYTAQAGAKFPIKWTAPES 95
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + +FSSKSDVWAFG+L+WE+ T G PY + V K+++G +E+P+ + +Y
Sbjct: 96 LAYVKFSSKSDVWAFGILLWEIATYGCSPYPGVDLQHVYGKLEQGYRMERPEAVLRNVYK 155
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+M CW +RPSF + E++
Sbjct: 156 LMHKCWEWRHTDRPSFTEIHEEM 178
>UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase
Yes; n=422; root|Rep: Proto-oncogene tyrosine-protein
kinase Yes - Homo sapiens (Human)
Length = 543
Score = 165 bits (401), Expect = 4e-40
Identities = 72/143 (50%), Positives = 99/143 (69%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MAY+ER NYIHRDL A N LVG+ V K+ADFGLAR + D++YT+ G KFPIKW PE
Sbjct: 384 MAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEA 443
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+ RF+ KSDVW+FG+L E+ T G+VPY + N EV+++V+RG + P+GC ++
Sbjct: 444 ALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHE 503
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+M CW P+ERP+F ++ L
Sbjct: 504 LMNLCWKKDPDERPTFEYIQSFL 526
>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1;
n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1
- Spongilla lacustris (Freshwater sponge)
Length = 505
Score = 163 bits (397), Expect = 1e-39
Identities = 70/143 (48%), Positives = 98/143 (68%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M+YLE+ NYIHRDLAARN LVG+ + KVADFGLAR + ++ Y + G KFPIKW PE
Sbjct: 347 MSYLEQQNYIHRDLAARNILVGEHGICKVADFGLARVIDEEIYEAHTGAKFPIKWTAPEA 406
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+ RF+ KSDVW+FGV+++E+ T G+ PY +TN EV++K+Q+ + P C + ++
Sbjct: 407 AMYNRFTIKSDVWSFGVVLYEIITYGRFPYPGMTNPEVLEKIQQNYRMPCPANCPKQFHD 466
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+M CW P RP+F L+ QL
Sbjct: 467 IMLDCWREDPASRPTFETLQWQL 489
>UniRef50_Q910A2 Cluster: Spleen protein tyrosine kinase; n=2; Danio
rerio|Rep: Spleen protein tyrosine kinase - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 586
Score = 163 bits (396), Expect = 1e-39
Identities = 67/145 (46%), Positives = 103/145 (71%), Gaps = 2/145 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAPP 58
M YLE HN++HRDLAARN L+ ++ K++DFGL++ + +D+ Y + G K+P+KW P
Sbjct: 433 MKYLEEHNFVHRDLAARNVLLVTQHYAKISDFGLSKALTEDENYYKAKGHGKWPLKWYAP 492
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E +N+ +FSSKSDVW+FGVLMWE F+ G+ PY + +EV+ ++ GQ + P C E+
Sbjct: 493 ECMNYLKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKGNEVIQMIENGQRMSAPPDCPPEM 552
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y++M+ CW + P+ERP F V++ +L
Sbjct: 553 YDLMKKCWTYKPDERPGFSVVEPRL 577
>UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14482, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 621
Score = 162 bits (394), Expect = 3e-39
Identities = 69/145 (47%), Positives = 105/145 (72%), Gaps = 2/145 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAPP 58
M YLE HN++HRDLAARN L+ ++ K++DFGL++ V +D+ Y + G K+P+KW P
Sbjct: 468 MKYLEEHNFVHRDLAARNVLLVTQHYAKISDFGLSKAVAEDKSYYKAKGHGKWPVKWYAP 527
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E +N+ +FSSKSDVW+FGVLMWE F+ G+ PY + +EV+ ++ GQ +E P C +E+
Sbjct: 528 ECINYFKFSSKSDVWSFGVLMWEAFSFGQKPYKGMKGNEVMQMIESGQRMEAPANCPSEM 587
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
++M+ACW + E+RPSF V++ +L
Sbjct: 588 SDLMQACWTYKVEDRPSFSVVEPRL 612
>UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma
mansoni|Rep: Src tyrosine kinase - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 162 bits (394), Expect = 3e-39
Identities = 70/143 (48%), Positives = 99/143 (69%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MAYLE +IHRDLAARN LVG+++ VK+ADFGLAR + + +Y + G +FPIKW PE
Sbjct: 454 MAYLESRRHIHRDLAARNVLVGEQHAVKIADFGLARMIHNREYVAHAGARFPIKWTSPEA 513
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
N++RF+ KSDVW+FG+L+ E+ T G+ PY + N+EV+ +V G + KP GC E+Y+
Sbjct: 514 ANYSRFTIKSDVWSFGILLTEIVTYGRSPYPGMHNAEVLRQVDAGYRMSKPPGCPPELYD 573
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+M CW +RPSF + +L
Sbjct: 574 LMLECWAADENKRPSFATIHFRL 596
>UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 921
Score = 160 bits (389), Expect = 1e-38
Identities = 69/147 (46%), Positives = 99/147 (67%), Gaps = 1/147 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK-FPIKWAPPE 59
MAYLE IHRDLAARNCLV + N VK++DFG++R D Y + GG + PIKW PE
Sbjct: 772 MAYLESKKCIHRDLAARNCLVAENNSVKISDFGMSRQDDDGVYLAEGGLRQIPIKWTAPE 831
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
LN+ R++++SDVW+FG+L+WE F+ G PY ++N + D+V++G + P C EI
Sbjct: 832 ALNYGRYTTQSDVWSFGILLWETFSLGLTPYMSMSNQQTRDEVEKGYRMPAPHACPVEIA 891
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVI 146
+M CW + P+ RPSF+ L+ +L+ I
Sbjct: 892 RIMNNCWQYDPQNRPSFKKLRAELSAI 918
>UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27;
Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK -
Homo sapiens (Human)
Length = 505
Score = 160 bits (389), Expect = 1e-38
Identities = 71/146 (48%), Positives = 99/146 (67%), Gaps = 3/146 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLAR-YVLDDQ--YTSSGGTKFPIKWAP 57
MAYLE NYIHRDLAARN LVG+ N+ KVADFGLAR + +D++ Y S K P+KW
Sbjct: 342 MAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTA 401
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + +FS KSDVW+FG+L++E+ T GK+PY +T ++V+ + + L +P C +
Sbjct: 402 PEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQ 461
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQL 143
YN+M CW P+ERP+F L+ +L
Sbjct: 462 FYNIMLECWNAEPKERPTFETLRWKL 487
>UniRef50_P04629 Cluster: High affinity nerve growth factor receptor
precursor; n=28; Eumetazoa|Rep: High affinity nerve
growth factor receptor precursor - Homo sapiens (Human)
Length = 796
Score = 160 bits (388), Expect = 1e-38
Identities = 66/150 (44%), Positives = 104/150 (69%), Gaps = 1/150 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPPE 59
M YL +++HRDLA RNCLVG VVK+ DFG++R + Y GG T PI+W PPE
Sbjct: 638 MVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPE 697
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + +F+++SDVW+FGV++WE+FT GK P+ +L+N+E +D + +G+ LE+P+ C E+Y
Sbjct: 698 SILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVY 757
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQS 149
+MR CW P++R S + + +L ++Q+
Sbjct: 758 AIMRGCWQREPQQRHSIKDVHARLQALAQA 787
>UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular
organisms|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 893
Score = 159 bits (386), Expect = 2e-38
Identities = 71/151 (47%), Positives = 100/151 (66%), Gaps = 1/151 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK-FPIKWAPPE 59
M YLE N IHRDLAARNCLVG+ ++VK++DFG++R YT GT+ PIKW PE
Sbjct: 742 MEYLESKNCIHRDLAARNCLVGENDIVKISDFGMSREEEGGMYTVQSGTRQIPIKWTAPE 801
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
LN+ R++S SDVW+FGVL++EVF+ G PY ++N+E +V G + P+GC EI+
Sbjct: 802 ALNYGRYTSASDVWSFGVLLYEVFSGGSTPYPGMSNAETRTQVDSGYRMPPPQGCPAEIH 861
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQSV 150
+M+ CW + E+RP F + E L + +V
Sbjct: 862 QIMQLCWAYDAEDRPKFGAVLESLKKLDGTV 892
>UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Rep:
Tyrosine kinase - Sycon raphanus
Length = 879
Score = 159 bits (385), Expect = 3e-38
Identities = 66/144 (45%), Positives = 101/144 (70%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK-FPIKWAPPE 59
M +LE+ N IHRDLAARNCLVGD NV+K++DFG++R D YT S G K PIKW PE
Sbjct: 730 MVFLEQRNCIHRDLAARNCLVGDNNVLKISDFGMSREEDDGIYTVSSGLKQIPIKWTSPE 789
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
LN+ R++++SDVW++G+L+WE +T G PY + N E ++++ + +P+ C + +Y
Sbjct: 790 ALNYGRYTTQSDVWSYGILLWETYTYGSGPYPGMNNRETRERIESNYRMPRPELCPHPVY 849
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+M +CW + P++RPSF + ++L
Sbjct: 850 KLMLSCWEYDPDKRPSFAEIYDKL 873
>UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF7099, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1000
Score = 158 bits (383), Expect = 6e-38
Identities = 66/137 (48%), Positives = 95/137 (69%), Gaps = 1/137 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
MAYL ++HRDLA RNCLVG+E VVK+ADFGL+R + D Y ++ PI+W PPE
Sbjct: 853 MAYLSERKFVHRDLATRNCLVGEEMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPE 912
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + R++++SD+WA+GV++WE+F+ G PY + + EV+ V+ G +L P+ C E+Y
Sbjct: 913 SIFYNRYTTESDIWAYGVVLWEIFSHGMQPYYGMGHEEVIYYVRDGHILSCPENCPLELY 972
Query: 120 NVMRACWGHTPEERPSF 136
N+MR CW P ERPSF
Sbjct: 973 NLMRLCWSSQPPERPSF 989
>UniRef50_Q2VXS7 Cluster: Proto-oncogene c-fes variant 4; n=77;
Eutheria|Rep: Proto-oncogene c-fes variant 4 - Homo
sapiens (Human)
Length = 752
Score = 157 bits (382), Expect = 7e-38
Identities = 68/147 (46%), Positives = 101/147 (68%), Gaps = 1/147 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK-FPIKWAPPE 59
M YLE IHRDLAARNCLV ++NV+K++DFG++R D Y +SGG++ P+KW PE
Sbjct: 601 MEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGSRQVPVKWTAPE 660
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
LN+ R+SS+SDVW+FG+L+WE F+ G PY L+N + + V++G L P+ C + ++
Sbjct: 661 ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVF 720
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVI 146
+M CW + P +RPSF + ++L I
Sbjct: 721 RLMEQCWAYEPGQRPSFSTIYQELQSI 747
>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2;
Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 747
Score = 157 bits (381), Expect = 1e-37
Identities = 74/145 (51%), Positives = 101/145 (69%), Gaps = 4/145 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE IHRDLAARN L+ +E V KV+DFGLAR D++YT+ +K PIKW PE
Sbjct: 596 MEYLEMKKVIHRDLAARNVLISEECVAKVSDFGLAR---DERYTADI-SKLPIKWTAPEA 651
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L +FS+K+D+W+FG+L+WE+++ G+VPY R+ ++VV V G +E P+GC EIY
Sbjct: 652 LKEGKFSNKTDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVGSGYKMEAPEGCPPEIYE 711
Query: 121 VMRACWGHTPEERPSFRVLKEQLAV 145
+MR W PE+RP+F LK +LAV
Sbjct: 712 MMRQAWDLVPEKRPTFAELKRRLAV 736
>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 485
Score = 156 bits (378), Expect = 2e-37
Identities = 65/147 (44%), Positives = 97/147 (65%), Gaps = 3/147 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE N++HRDLAARN L+ ++NV KV+DFGLA+ G K P+KW PE
Sbjct: 336 MVYLESQNFVHRDLAARNVLIAEDNVAKVSDFGLAK---SSSNVKQEGAKLPVKWTAPEA 392
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L +FS+K+DVW+FGVL+WE+++ G+VPY R+ +V + V+ G +E P GC ++IY
Sbjct: 393 LRENKFSNKTDVWSFGVLLWEIYSYGRVPYPRVPVEDVANHVENGYRMESPDGCPDQIYK 452
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVIS 147
+M CW P +RP+F +++ L ++
Sbjct: 453 IMMDCWEKDPSQRPNFTRIEKALESVA 479
>UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine protein
kinase precursor; n=53; Euteleostomi|Rep: Muscle,
skeletal receptor tyrosine protein kinase precursor -
Homo sapiens (Human)
Length = 869
Score = 156 bits (378), Expect = 2e-37
Identities = 65/137 (47%), Positives = 94/137 (68%), Gaps = 1/137 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
MAYL ++HRDLA RNCLVG+ VVK+ADFGL+R + D Y ++ PI+W PPE
Sbjct: 713 MAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPE 772
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + R++++SDVWA+GV++WE+F+ G PY + + EV+ V+ G +L P+ C E+Y
Sbjct: 773 SIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELY 832
Query: 120 NVMRACWGHTPEERPSF 136
N+MR CW P +RPSF
Sbjct: 833 NLMRLCWSKLPADRPSF 849
>UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020257 - Anopheles gambiae
str. PEST
Length = 1192
Score = 155 bits (377), Expect = 3e-37
Identities = 66/137 (48%), Positives = 94/137 (68%), Gaps = 3/137 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK-FPIKWAPPE 59
M YLE N IHRDLAARNCL+G EN+VK++DFG++R +++Y SGG K PIKW PE
Sbjct: 1042 MRYLESKNCIHRDLAARNCLIGSENIVKISDFGMSRE--EEEYIVSGGMKQIPIKWTAPE 1099
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
LNF +++S DVW++G+L+WE+F+ G PY ++NS +++ G + P+G E+Y
Sbjct: 1100 ALNFGKYTSLCDVWSYGILVWEIFSRGDTPYSGMSNSMARERIDEGYRMPAPEGAPPEMY 1159
Query: 120 NVMRACWGHTPEERPSF 136
+M CW + PE RP F
Sbjct: 1160 RLMLKCWSYEPESRPHF 1176
>UniRef50_UPI00015A7C25 Cluster: UPI00015A7C25 related cluster; n=3;
Danio rerio|Rep: UPI00015A7C25 UniRef100 entry - Danio
rerio
Length = 759
Score = 155 bits (376), Expect = 4e-37
Identities = 72/153 (47%), Positives = 103/153 (67%), Gaps = 7/153 (4%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK-FPIKWAPPE 59
+AYLE IHRD+AARNCLVG+E+VVK++DFG++R D Y+++GG K P+KW PE
Sbjct: 602 LAYLESKKCIHRDVAARNCLVGEESVVKISDFGMSREEQDGVYSATGGMKQIPVKWTAPE 661
Query: 60 VLNF---TRFSSKSDVWAFGVLMWEVFTCGKVPY---GRLTNSEVVDKVQRGQVLEKPKG 113
LN+ R++++SDVW+FGVL+WE F+ G PY ++N + D+V+RG + P
Sbjct: 662 ALNYGSPGRYTTESDVWSFGVLLWETFSRGVTPYTIPTVMSNQQTRDEVERGYRMPAPNN 721
Query: 114 CINEIYNVMRACWGHTPEERPSFRVLKEQLAVI 146
C +EIY +M CW + P +RPSF LK L +
Sbjct: 722 CPDEIYTLMCQCWQYDPRKRPSFLKLKADLGAL 754
>UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2;
Caenorhabditis|Rep: C-terminal src kinase protein 1 -
Caenorhabditis elegans
Length = 539
Score = 155 bits (376), Expect = 4e-37
Identities = 69/150 (46%), Positives = 101/150 (67%), Gaps = 1/150 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE +HRDLAARN L+ D+ V KV+DFGLA+ + S+ G KFPIKW PE
Sbjct: 391 MCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSASG-KFPIKWTAPEA 449
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L ++F++KSDVW+FG+L+WE+F+ G+VPY R+ +VV +++G +E P+GC EI+
Sbjct: 450 LRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFK 509
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQSV 150
VM W + ++RPSF + ++L I +V
Sbjct: 510 VMNETWALSAQDRPSFGQVLQRLTTIRNTV 539
>UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2 -
Tribolium castaneum
Length = 473
Score = 155 bits (375), Expect = 5e-37
Identities = 66/141 (46%), Positives = 95/141 (67%), Gaps = 2/141 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE IHRDLAARN L+G+ N+ K+ DFGLAR + D++Y G++FP+KW PE
Sbjct: 313 MEYLESKQLIHRDLAARNVLIGENNIAKICDFGLARVIEDNEYCPKQGSRFPVKWTAPEA 372
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCI--NEI 118
+ + +FS KSDVW++G+ + E+FT G+VPY + EV+D V++G + KP + +EI
Sbjct: 373 IVYGKFSIKSDVWSYGIFLMELFTYGQVPYPGMHGREVIDMVEKGYRMGKPTSHVLPDEI 432
Query: 119 YNVMRACWGHTPEERPSFRVL 139
Y++M CW PE RP+F L
Sbjct: 433 YSIMLQCWDAKPENRPTFEFL 453
>UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine protein
kinase precursor; n=18; Gnathostomata|Rep: Muscle,
skeletal receptor tyrosine protein kinase precursor -
Gallus gallus (Chicken)
Length = 947
Score = 155 bits (375), Expect = 5e-37
Identities = 65/137 (47%), Positives = 93/137 (67%), Gaps = 1/137 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
MAYL ++HRDLA RNCLVG+ VVK+ADFGL+R + D Y ++ PI+W PPE
Sbjct: 791 MAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNMYSADYYKANENDAIPIRWMPPE 850
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + R++++SDVWA+GV++WE+F+ G PY + + EV+ V+ G +L P C E+Y
Sbjct: 851 SIFYNRYTTESDVWAYGVVLWEIFSYGMQPYYGMAHEEVIYYVRDGNILSCPDNCPLELY 910
Query: 120 NVMRACWGHTPEERPSF 136
N+MR CW P +RPSF
Sbjct: 911 NLMRLCWSKLPADRPSF 927
>UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21;
Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo
sapiens (Human)
Length = 450
Score = 155 bits (375), Expect = 5e-37
Identities = 69/143 (48%), Positives = 96/143 (67%), Gaps = 4/143 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE +N++HRDLAARN LV ++NV KV+DFGL + Q T K P+KW PE
Sbjct: 302 MEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTG----KLPVKWTAPEA 357
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L +FS+KSDVW+FG+L+WE+++ G+VPY R+ +VV +V++G ++ P GC +Y
Sbjct: 358 LREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYE 417
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
VM+ CW RPSF L+EQL
Sbjct: 418 VMKNCWHLDAAMRPSFLQLREQL 440
>UniRef50_Q70W05 Cluster: Src protein; n=1; Ciona intestinalis|Rep:
Src protein - Ciona intestinalis (Transparent sea
squirt)
Length = 355
Score = 154 bits (374), Expect = 7e-37
Identities = 70/144 (48%), Positives = 96/144 (66%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
M YLE ++YIHRDLAARN LVG N+ K+ADFGLAR +D Y + G +FPI+W PE
Sbjct: 202 MVYLEVNDYIHRDLAARNILVGKNNICKIADFGLARVTQGNDIYQAKVGAEFPIRWTAPE 261
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+F+ KSDVW+FG+L+ E+ G+VPY EV+++V+RG +EK + C ++Y
Sbjct: 262 AATMQQFTIKSDVWSFGILLTEIIGNGRVPYAGFQTFEVLEQVERGYRMEKLEKCSEQLY 321
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
++M ACW P +RPSF L QL
Sbjct: 322 DIMMACWHKDPNQRPSFESLVMQL 345
>UniRef50_Q05397 Cluster: Focal adhesion kinase 1; n=111;
Euteleostomi|Rep: Focal adhesion kinase 1 - Homo sapiens
(Human)
Length = 1052
Score = 154 bits (374), Expect = 7e-37
Identities = 66/146 (45%), Positives = 92/146 (63%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
+AYLE ++HRD+AARN LV + VK+ DFGL+RY+ D Y + K PIKW PE
Sbjct: 534 LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPES 593
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+NF RF+S SDVW FGV MWE+ G P+ + N++V+ +++ G+ L P C +Y+
Sbjct: 594 INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS 653
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVI 146
+M CW + P RP F LK QL+ I
Sbjct: 654 LMTKCWAYDPSRRPRFTELKAQLSTI 679
>UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6;
Endopterygota|Rep: Tyrosine-protein kinase Src64B -
Drosophila melanogaster (Fruit fly)
Length = 552
Score = 154 bits (373), Expect = 9e-37
Identities = 66/141 (46%), Positives = 95/141 (67%), Gaps = 2/141 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE IHRDLAARN L+G+ NV K+ DFGLAR + DD+Y G++FP+KW PE
Sbjct: 392 MEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEA 451
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCI--NEI 118
+ + +FS KSDVW++G+L+ E+FT G+VPY + + EV++ ++RG + KP + I
Sbjct: 452 IIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNI 511
Query: 119 YNVMRACWGHTPEERPSFRVL 139
Y ++ CW PE+RP+F L
Sbjct: 512 YQLLLQCWDAVPEKRPTFEFL 532
>UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase BLK - Homo
sapiens (Human)
Length = 505
Score = 154 bits (373), Expect = 9e-37
Identities = 72/144 (50%), Positives = 97/144 (67%), Gaps = 2/144 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MAY+ER N IHRDL A N LV + K+ADFGLAR ++D +YT+ G KFPIKW PE
Sbjct: 348 MAYIERMNSIHRDLRAANILVSEALCCKIADFGLAR-IIDSEYTAQEGAKFPIKWTAPEA 406
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY- 119
++F F+ K+DVW+FGVL+ EV T G+VPY ++N EV+ ++RG + +P C E+Y
Sbjct: 407 IHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELYR 466
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
V+ CW PEERP+F L+ L
Sbjct: 467 GVIAECWRSRPEERPTFEFLQSVL 490
>UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma
mansoni|Rep: Tyrosine kinase 5 - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 153 bits (372), Expect = 1e-36
Identities = 72/143 (50%), Positives = 95/143 (66%), Gaps = 2/143 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAPP 58
MAYLE+ +YIHRDLAARN LVG+ N VKVADFGLAR V D Y + TKFPIKW P
Sbjct: 411 MAYLEKEHYIHRDLAARNILVGENNCVKVADFGLARMVEDHYCTYMAQKSTKFPIKWTAP 470
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E RF+ KSDVW+FG++++E+ T G+VPY + N+E + +V G + +P C I
Sbjct: 471 EAALMGRFTIKSDVWSFGIVIYELITLGQVPYPSMNNTETLHQVSTGYRMPRPVNCPQPI 530
Query: 119 YNVMRACWGHTPEERPSFRVLKE 141
Y+++ W PE+RP+F L E
Sbjct: 531 YDMLLRIWDSCPEKRPTFSSLFE 553
>UniRef50_Q4SQ93 Cluster: Tyrosine-protein kinase receptor; n=2;
Tetraodontidae|Rep: Tyrosine-protein kinase receptor -
Tetraodon nigroviridis (Green puffer)
Length = 822
Score = 152 bits (369), Expect = 3e-36
Identities = 63/150 (42%), Positives = 103/150 (68%), Gaps = 1/150 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPPE 59
M YL +++HRDLA RNCLVG+ +VK+ DFG++R V Y GG T PI+W PPE
Sbjct: 664 MVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPE 723
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + RF+++SDVW+ GV++WE+FT GK P+ +L+N+EV++ + +G+VL++P+ C E+Y
Sbjct: 724 SIMYRRFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPKEVY 783
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQS 149
++M CW P R + + + L ++++
Sbjct: 784 DLMLGCWHREPYMRLNIKEIYGMLQGLAKA 813
>UniRef50_Q9Y1Y3 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 893
Score = 152 bits (369), Expect = 3e-36
Identities = 65/149 (43%), Positives = 97/149 (65%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YL Y+HRDLAARN LV + V KVADFGL+R +D+Y G K P++W PE
Sbjct: 647 MQYLSEVGYVHRDLAARNILVSKDEVCKVADFGLSRETTNDEYDVKKGGKIPVRWTAPEA 706
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+++ +F++ SDVW++GVL+WEV + G+ PY N V+DK++ G L+KPK C + +Y
Sbjct: 707 ISYRKFTTASDVWSYGVLLWEVMSYGQQPYEDWDNQMVLDKLESGYRLQKPKDCPSTVYE 766
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQS 149
+M++CW +RP+F+ L L + +S
Sbjct: 767 LMQSCWSAEHTDRPTFKELVRLLDAMLES 795
>UniRef50_Q91987 Cluster: BDNF/NT-3 growth factors receptor
precursor; n=17; Euteleostomi|Rep: BDNF/NT-3 growth
factors receptor precursor - Gallus gallus (Chicken)
Length = 818
Score = 152 bits (369), Expect = 3e-36
Identities = 62/150 (41%), Positives = 103/150 (68%), Gaps = 1/150 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPPE 59
M YL +++HRDLA RNCLVG+ +VK+ DFG++R V Y GG T PI+W PPE
Sbjct: 660 MVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPE 719
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + +F+++SDVW+ GV++WE+FT GK P+ +L+N+EV++ + +G+VL++P+ C E+Y
Sbjct: 720 SIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPKEVY 779
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQS 149
++M CW P R + + + L ++++
Sbjct: 780 DLMLGCWQREPHMRLNIKEIHSLLQNLAKA 809
>UniRef50_Q16620 Cluster: BDNF/NT-3 growth factors receptor
precursor; n=73; Gnathostomata|Rep: BDNF/NT-3 growth
factors receptor precursor - Homo sapiens (Human)
Length = 822
Score = 152 bits (368), Expect = 4e-36
Identities = 61/138 (44%), Positives = 96/138 (69%), Gaps = 1/138 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPPE 59
M YL +++HRDLA RNCLVG+ +VK+ DFG++R V Y GG T PI+W PPE
Sbjct: 664 MVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPE 723
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + +F+++SDVW+ GV++WE+FT GK P+ +L+N+EV++ + +G+VL++P+ C E+Y
Sbjct: 724 SIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVY 783
Query: 120 NVMRACWGHTPEERPSFR 137
+M CW P R + +
Sbjct: 784 ELMLGCWQREPHMRKNIK 801
>UniRef50_UPI00015A61DF Cluster: UPI00015A61DF related cluster; n=2;
Danio rerio|Rep: UPI00015A61DF UniRef100 entry - Danio
rerio
Length = 985
Score = 151 bits (366), Expect = 6e-36
Identities = 63/139 (45%), Positives = 95/139 (68%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
+AYLE N +HRD+A RN LV + VK+ DFGL+RY+ +++Y + T+ PIKW PE
Sbjct: 473 LAYLEGVNMVHRDIAVRNVLVAKVDCVKLGDFGLSRYIEEEEYYKASVTRLPIKWMAPES 532
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+NF RF+S SDVW F V MWE+ + G+ P+ L N +V++++++G L KP+ C +Y+
Sbjct: 533 INFRRFTSASDVWMFAVCMWEIMSGGQQPFFWLENKDVINQLEQGMRLPKPERCPPTLYS 592
Query: 121 VMRACWGHTPEERPSFRVL 139
+M CW ++P +RPSF L
Sbjct: 593 LMTRCWSYSPRDRPSFTEL 611
>UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2;
Culicidae|Rep: Tyrosine-protein kinase shark - Aedes
aegypti (Yellowfever mosquito)
Length = 939
Score = 150 bits (364), Expect = 1e-35
Identities = 64/141 (45%), Positives = 93/141 (65%), Gaps = 2/141 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL--DDQYTSSGGTKFPIKWAPP 58
M YLE+H+++HRDLAARN L+ N K++DFGL+R + DD Y +S G K+PIKW P
Sbjct: 772 MQYLEQHHFVHRDLAARNILLASRNQAKISDFGLSRAIGAGDDYYRASQGGKWPIKWYAP 831
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E N+ FS SDVW+FGV MWE+++ G PY + +V+ ++ GQ L +P C +
Sbjct: 832 ESFNYGTFSHASDVWSFGVTMWEMYSLGAPPYQDMKGVDVIKLIENGQRLSQPDLCPENV 891
Query: 119 YNVMRACWGHTPEERPSFRVL 139
+ VM+ CW + P+ RP+F+ L
Sbjct: 892 FEVMKNCWNYNPKSRPTFKFL 912
>UniRef50_A7SI92 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 312
Score = 150 bits (364), Expect = 1e-35
Identities = 65/143 (45%), Positives = 91/143 (63%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YL R ++HRDLAARN LVGD V KVADFGL R++ +D Y K P+KW E
Sbjct: 155 MEYLARRGFVHRDLAARNVLVGDNKVAKVADFGLTRHMYEDLYQGKTSRKLPLKWMSIEA 214
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+ F+S+SDVWA+GV +WE+ T G PY + N E++ ++ G +EKP C +++Y
Sbjct: 215 IFDQAFTSQSDVWAYGVFLWELVTLGGTPYPTIGNRELLKLLKEGYRMEKPDMCNDDLYT 274
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+M +CW PE+RP+F L+ L
Sbjct: 275 IMLSCWKDKPEDRPTFENLRSTL 297
>UniRef50_P08923 Cluster: Leukocyte tyrosine kinase receptor
precursor; n=8; Amniota|Rep: Leukocyte tyrosine kinase
receptor precursor - Mus musculus (Mouse)
Length = 888
Score = 150 bits (364), Expect = 1e-35
Identities = 67/150 (44%), Positives = 94/150 (62%), Gaps = 4/150 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPP 58
YLE +++IHRD+AARNCL+ G V K+ DFG+AR + Y GG T P+KW PP
Sbjct: 629 YLEENHFIHRDIAARNCLLSCSGASRVAKIGDFGMARDIYQASYYRKGGRTLLPVKWMPP 688
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E L F+SK+D W+FGVL+WE+F+ G +PY TN EV+D + G ++ P+ C +
Sbjct: 689 EALLEGLFTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGNRMDPPRNCPGPV 748
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQ 148
Y +M CW H PE RP F + E++ +Q
Sbjct: 749 YRIMTQCWQHQPELRPDFGSILERIQYCTQ 778
>UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,
isoform B; n=3; Endopterygota|Rep: PREDICTED: similar to
CG8874-PB, isoform B - Tribolium castaneum
Length = 801
Score = 150 bits (363), Expect = 1e-35
Identities = 70/153 (45%), Positives = 100/153 (65%), Gaps = 7/153 (4%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK-FPIKWAPPE 59
M YLE N IHRDLAARNCLVG NVVK++DFG++R +++Y S G K PIKW PE
Sbjct: 648 MRYLESKNCIHRDLAARNCLVGYNNVVKISDFGMSRE--EEEYIVSDGMKQIPIKWTAPE 705
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
LNF +++S DVW++G+L WE+F+ G PY L+NS+ +K+ G + P +E+Y
Sbjct: 706 ALNFGKYTSLCDVWSYGILCWEIFSRGGTPYSGLSNSKAREKIDAGYRMPAPDNTPDEMY 765
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQSVLA 152
+M CW + PE RP+F EQ+ + +++ A
Sbjct: 766 RLMLRCWEYKPENRPNF----EQIYTVVETLCA 794
>UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p
- Drosophila melanogaster (Fruit fly)
Length = 847
Score = 150 bits (363), Expect = 1e-35
Identities = 70/149 (46%), Positives = 100/149 (67%), Gaps = 4/149 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE +HRDLAARN L+ ++ V KV+DFGLAR ++ Y G K PIKW PE
Sbjct: 701 MEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAR---EECYNLDVG-KLPIKWTAPEA 756
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L RFS+KSD+W+FG+L+WE+++ G+VPY R+ ++VV V+ G +E P+GC EIY
Sbjct: 757 LKNGRFSNKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYE 816
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQS 149
+MR W P +RP+F LK +L +++ +
Sbjct: 817 MMRQAWDLNPAKRPTFAELKVKLQLLNNA 845
>UniRef50_A6P4V4 Cluster: Tyrosine-protein kinase receptor; n=2; Homo
sapiens|Rep: Tyrosine-protein kinase receptor - Homo
sapiens (Human)
Length = 1310
Score = 150 bits (363), Expect = 1e-35
Identities = 65/150 (43%), Positives = 95/150 (63%), Gaps = 4/150 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPP 58
YLE +++IHRD+AARNCL+ G V K+ DFG+AR + Y GG P+KW PP
Sbjct: 929 YLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPP 988
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E F+SK+D W+FGVL+WE+F+ G +PY +N EV++ V G ++ PK C +
Sbjct: 989 EAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPV 1048
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQ 148
Y +M CW H PE+RP+F ++ E++ +Q
Sbjct: 1049 YRIMTQCWQHQPEDRPNFAIILERIEYCTQ 1078
>UniRef50_Q9UM73 Cluster: ALK tyrosine kinase receptor precursor;
n=37; Euteleostomi|Rep: ALK tyrosine kinase receptor
precursor - Homo sapiens (Human)
Length = 1620
Score = 150 bits (363), Expect = 1e-35
Identities = 65/150 (43%), Positives = 95/150 (63%), Gaps = 4/150 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPP 58
YLE +++IHRD+AARNCL+ G V K+ DFG+AR + Y GG P+KW PP
Sbjct: 1239 YLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPP 1298
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E F+SK+D W+FGVL+WE+F+ G +PY +N EV++ V G ++ PK C +
Sbjct: 1299 EAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPV 1358
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQ 148
Y +M CW H PE+RP+F ++ E++ +Q
Sbjct: 1359 YRIMTQCWQHQPEDRPNFAIILERIEYCTQ 1388
>UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG18247-PA - Tribolium castaneum
Length = 725
Score = 149 bits (362), Expect = 2e-35
Identities = 65/143 (45%), Positives = 95/143 (66%), Gaps = 2/143 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAPP 58
M YLE +IHRDLAARN L+ ++ K++DFGL+R + D Y + G K+P+KW P
Sbjct: 562 MNYLEEQRFIHRDLAARNILLASQHQAKISDFGLSRALAADHEYYRALQGGKWPLKWYAP 621
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E N+ +FS KSDVW+FGV +WE+++ G VPYG L S+ + ++ G+ L++P C + I
Sbjct: 622 ESYNYGQFSHKSDVWSFGVAIWEMYSFGDVPYGELKGSDAIKIIEDGERLKQPDACPDHI 681
Query: 119 YNVMRACWGHTPEERPSFRVLKE 141
Y +MR CW + E RP+F+ L E
Sbjct: 682 YEIMRRCWEYDAENRPTFKELLE 704
>UniRef50_Q5TUS8 Cluster: Tyrosine-protein kinase receptor; n=1;
Anopheles gambiae str. PEST|Rep: Tyrosine-protein kinase
receptor - Anopheles gambiae str. PEST
Length = 2075
Score = 149 bits (362), Expect = 2e-35
Identities = 70/149 (46%), Positives = 96/149 (64%), Gaps = 5/149 (3%)
Query: 3 YLERHNYIHRDLAARNCLVGD----ENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAP 57
YLE +++HRDLA RNCLV + VVK+ DFGLAR + +D Y G P++W
Sbjct: 1927 YLEEMHFVHRDLACRNCLVSSTDPRDRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMS 1986
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE L F+S+SD+WAFGVL+WE+ T G+ PY N EV++ V+ G L++PK C NE
Sbjct: 1987 PESLVDGVFTSQSDIWAFGVLLWEIMTLGEQPYQAKNNVEVLNHVREGGHLDRPKVCPNE 2046
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVI 146
+Y +M+ CW +PEERP+FR E L +
Sbjct: 2047 MYELMKYCWKFSPEERPTFRYCLEVLRAL 2075
>UniRef50_O76148 Cluster: Tyrosine-protein kinase receptor; n=1;
Anopheles sp.|Rep: Tyrosine-protein kinase receptor -
Anopheles sp
Length = 863
Score = 149 bits (362), Expect = 2e-35
Identities = 72/156 (46%), Positives = 98/156 (62%), Gaps = 5/156 (3%)
Query: 3 YLERHNYIHRDLAARNCLVGD----ENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAP 57
YLE +++HRDLA RNCLV + VVK+ DFGLAR + +D Y G P++W
Sbjct: 572 YLEEMHFVHRDLACRNCLVSSTDPRDRVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMS 631
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE L F+S+SD+WAFGVL+WE+ T G+ PY N EV++ V+ G L++PK C NE
Sbjct: 632 PESLVDGVFTSQSDIWAFGVLLWEIMTLGEQPYQAKNNVEVLNHVREGGHLDRPKVCPNE 691
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
+Y +M+ CW +PEERP+FR E L Q+ D
Sbjct: 692 MYELMKYCWKFSPEERPTFRYCLEVLERRCQNTSED 727
>UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;
n=3; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 510
Score = 149 bits (361), Expect = 3e-35
Identities = 71/139 (51%), Positives = 91/139 (65%), Gaps = 1/139 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MAYLE N IHRDLAARN LVG + KVAD GLAR V + Y SS + P KW+ PE
Sbjct: 351 MAYLEEQNSIHRDLAARNVLVGANYICKVADLGLARIVKESVY-SSEDAQIPYKWSAPEA 409
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
++ RFS+KSDVW+FGVL++E+FT G VPY +N EV + + G + P C + IY+
Sbjct: 410 ISHGRFSNKSDVWSFGVLLYEMFTYGGVPYPAFSNIEVYNMITSGYRMPAPPNCPSHIYD 469
Query: 121 VMRACWGHTPEERPSFRVL 139
+M CW ++ EERP F L
Sbjct: 470 IMLMCWRYSAEERPDFSEL 488
>UniRef50_Q4RY69 Cluster: Chromosome 3 SCAF14978, whole genome
shotgun sequence; n=3; Fungi/Metazoa group|Rep:
Chromosome 3 SCAF14978, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 958
Score = 149 bits (361), Expect = 3e-35
Identities = 64/146 (43%), Positives = 96/146 (65%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
+AYLE N +HRD+A RN LV VK+ DFGL+RY+ +++Y + ++ PIKW PE
Sbjct: 498 LAYLEGLNVVHRDIAVRNILVASPLCVKLGDFGLSRYIEEEEYYKASASRLPIKWMAPES 557
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+NF RF++ SDVW FGV +WE+F+ + P+ L NS+V+D+++ G L KP+ C +Y+
Sbjct: 558 INFRRFTTASDVWMFGVCVWEIFSMAQQPFFWLENSQVIDQLESGIRLPKPQLCPPTVYS 617
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVI 146
++ +CW H P RP F L L+ I
Sbjct: 618 LVSSCWSHEPHLRPQFSHLACSLSEI 643
>UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep:
Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 511
Score = 149 bits (361), Expect = 3e-35
Identities = 71/144 (49%), Positives = 93/144 (64%), Gaps = 2/144 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MAYLE +N IHRDLAARN LVGD V K+ADFGLAR + + Y S K P KW PE
Sbjct: 357 MAYLEANNSIHRDLAARNVLVGDGYVCKIADFGLARIIKEPVYLSD-DKKIPYKWTAPEA 415
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQV-LEKPKGCINEIY 119
+ +SSKSDVW+FG+L++E+ T G +PY + EV D + + + P C IY
Sbjct: 416 IGHGTYSSKSDVWSFGILLYEIVTHGGIPYPGVNTGEVYDLITKENYRMPSPPKCPQAIY 475
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
N+MRACW +RP+F+VLK++L
Sbjct: 476 NIMRACWRIESVDRPNFKVLKDEL 499
>UniRef50_UPI0000E47C0F Cluster: PREDICTED: similar to focal
adhesion kinase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to focal adhesion kinase -
Strongylocentrotus purpuratus
Length = 575
Score = 149 bits (360), Expect = 3e-35
Identities = 64/143 (44%), Positives = 93/143 (65%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
++YLE ++HRD+AARN LV ++ VK+ DFGL+R + D Y + K PIKW PE
Sbjct: 88 LSYLESKKFVHRDIAARNLLVVAKDNVKLGDFGLSRLLHDHSYYKASKGKLPIKWMAPES 147
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+NF RF+S SDVW FGV MWE+ G P+ + N+EV+ +++ G+ L P C +Y+
Sbjct: 148 INFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNEVIGRIENGERLPMPAACPPTLYS 207
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
VM CW + P +RP+F+ LK +L
Sbjct: 208 VMTLCWSYEPSKRPNFKDLKTRL 230
>UniRef50_Q7Z1D3 Cluster: Focal adhesion kinase; n=1; Lytechinus
variegatus|Rep: Focal adhesion kinase - Lytechinus
variegatus (Sea urchin)
Length = 1006
Score = 149 bits (360), Expect = 3e-35
Identities = 64/143 (44%), Positives = 93/143 (65%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
++YLE ++HRD+AARN LV ++ VK+ DFGL+R + D Y + K PIKW PE
Sbjct: 549 LSYLESKKFVHRDIAARNLLVVAKDNVKLGDFGLSRLLHDHSYYKASKGKLPIKWMAPES 608
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+NF RF+S SDVW FGV MWE+ G P+ + N+EV+ +++ G+ L P C +Y+
Sbjct: 609 INFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNEVIGRIENGERLPMPAACPPTLYS 668
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
VM CW + P +RP+F+ LK +L
Sbjct: 669 VMTLCWSYEPSKRPNFKDLKTRL 691
>UniRef50_Q5MCM8 Cluster: Protein-tyrosine kinase; n=2;
Anthomedusae|Rep: Protein-tyrosine kinase - Hydractinia
echinata (Snail fur) (Hermit crab hydroid)
Length = 1162
Score = 149 bits (360), Expect = 3e-35
Identities = 66/148 (44%), Positives = 98/148 (66%), Gaps = 3/148 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAPP 58
++YLE N++HRD+AARN L D + +K+ADFGL+R++ ++Q Y +S G K PIKW P
Sbjct: 547 LSYLESRNFVHRDIAARNILAADPHTIKLADFGLSRWIDEEQSYYKASKG-KLPIKWMAP 605
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E +NF RFSS SDVW FGV WE+ G P+ + N +V+ K++ G+ L P C +
Sbjct: 606 ESINFRRFSSASDVWMFGVCCWEILMYGVKPFQGVPNEKVIGKIENGERLPLPPNCAPTL 665
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVI 146
Y++M W + P +RP+F+ LK +L+ I
Sbjct: 666 YHLMTESWHYEPSKRPTFQELKSRLSQI 693
>UniRef50_UPI00015B5971 Cluster: PREDICTED: similar to leukocyte
receptor tyrosine protein kinase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to leukocyte receptor
tyrosine protein kinase - Nasonia vitripennis
Length = 1472
Score = 148 bits (359), Expect = 5e-35
Identities = 71/150 (47%), Positives = 92/150 (61%), Gaps = 4/150 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPP 58
Y+E +IHRD+AARNCL+ G VVK+ADFG+AR + D Y G PIKW PP
Sbjct: 1041 YMEEARFIHRDIAARNCLLSCKGPGRVVKIADFGMARDIYRSDYYRKGGKAMLPIKWMPP 1100
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E F++K+DVWAFGVL+WE+ + G +PY N EV+ V G LE+P GC + I
Sbjct: 1101 ESFLDGIFTTKTDVWAFGVLLWEIMSFGYMPYTGCANREVMSMVTSGGRLERPAGCPDPI 1160
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQ 148
Y +M CW PEERPSF + E++ Q
Sbjct: 1161 YGIMTRCWHPHPEERPSFSSIVERIGYCLQ 1190
>UniRef50_UPI0000D569CE Cluster: PREDICTED: similar to CG10023-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG10023-PA, isoform A - Tribolium castaneum
Length = 1106
Score = 148 bits (359), Expect = 5e-35
Identities = 68/145 (46%), Positives = 94/145 (64%), Gaps = 3/145 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAPP 58
++YLE ++HRD+AARN LV VK+ DFGL+R + DDQ Y +S G K PIKW P
Sbjct: 540 LSYLESKKFVHRDIAARNVLVSSHTSVKLGDFGLSRSMNDDQSYYKASKG-KLPIKWMSP 598
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E +NF RF+ SDVW FGV MWE+ G P+ + N+EV+ K++ G+ L P C +
Sbjct: 599 ESINFRRFTIASDVWMFGVCMWEILMYGIKPFQGVKNNEVLTKIENGERLALPPNCPPRL 658
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y++M CW + P +RPSF+ +KE L
Sbjct: 659 YSLMSQCWSYEPSKRPSFKEIKEIL 683
>UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -
Caenorhabditis elegans
Length = 533
Score = 148 bits (359), Expect = 5e-35
Identities = 72/145 (49%), Positives = 96/145 (66%), Gaps = 6/145 (4%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDE----NVVKVADFGLARYVLD-DQYTSSGGTKFPIKW 55
M YLE +HRDLAARN LVGD+ VVKVADFGLAR +++ D Y + G KFPIKW
Sbjct: 369 MMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKW 428
Query: 56 APPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCI 115
PE F+ KSDVW++G+L++E+ T G+VPY + N EVV++V+ G + P+GC
Sbjct: 429 TAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPRGCP 488
Query: 116 NEIY-NVMRACWGHTPEERPSFRVL 139
+IY V+ CW TP+ RP+F L
Sbjct: 489 EQIYEEVLLKCWDKTPDRRPTFDTL 513
>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
tyrosine kinase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to protein tyrosine kinase - Nasonia
vitripennis
Length = 739
Score = 148 bits (358), Expect = 6e-35
Identities = 62/140 (44%), Positives = 96/140 (68%), Gaps = 1/140 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLAR-YVLDDQYTSSGGTKFPIKWAPPE 59
M YLE +HRDLAARN L+ ++ K++DFGL+R + +D Y ++ G K+PIKW PE
Sbjct: 577 MKYLEEIRLVHRDLAARNILLASKHQAKISDFGLSRTFGSNDYYKATAGGKWPIKWYAPE 636
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
N+ FS SDVW++G+ +WE+F+ G+ PYG +EV+D V++G L +P+ C + +Y
Sbjct: 637 SYNYGTFSHASDVWSYGITLWEMFSYGEQPYGDRRGTEVIDLVEKGDRLAQPEQCPDHVY 696
Query: 120 NVMRACWGHTPEERPSFRVL 139
VM+ CW ++P +RP+F+ L
Sbjct: 697 KVMQKCWSYSPADRPTFQEL 716
>UniRef50_Q7KJ08 Cluster: Receptor protein tyrosine kinase ALK splice
variant A; n=9; Diptera|Rep: Receptor protein tyrosine
kinase ALK splice variant A - Drosophila melanogaster
(Fruit fly)
Length = 1701
Score = 148 bits (358), Expect = 6e-35
Identities = 71/150 (47%), Positives = 93/150 (62%), Gaps = 4/150 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPP 58
Y+E +IHRD+AARNCL+ G VVK+ADFG++R + D Y G PIKW PP
Sbjct: 1316 YMESKRFIHRDIAARNCLLSSKGPGRVVKIADFGMSRDIYRSDYYRKGGKAMLPIKWMPP 1375
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E F+SK+DVW+FG+L+WEVF+ G+ PY N++V++ V RG L P C I
Sbjct: 1376 EAFLDGIFTSKTDVWSFGILLWEVFSLGRSPYPGQHNTQVMELVVRGGRLGSPTECPVSI 1435
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQ 148
Y VM CW TPE+RP+F L E L +Q
Sbjct: 1436 YKVMADCWNPTPEDRPTFITLLEHLTACTQ 1465
>UniRef50_Q14289 Cluster: Protein tyrosine kinase 2 beta; n=47;
Euteleostomi|Rep: Protein tyrosine kinase 2 beta - Homo
sapiens (Human)
Length = 1009
Score = 148 bits (358), Expect = 6e-35
Identities = 66/148 (44%), Positives = 91/148 (61%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MAYLE N +HRD+A RN LV VK+ DFGL+RY+ D+ Y + T+ PIKW PE
Sbjct: 537 MAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPES 596
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+NF RF++ SDVW F V MWE+ + GK P+ L N +V+ +++G L KP C +Y
Sbjct: 597 INFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYT 656
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQ 148
+M CW + P +RP F L L+ + Q
Sbjct: 657 LMTRCWDYDPSDRPRFTELVCSLSDVYQ 684
>UniRef50_UPI0000DB6D22 Cluster: PREDICTED: similar to Alk CG8250-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to Alk
CG8250-PA - Apis mellifera
Length = 1436
Score = 147 bits (357), Expect = 8e-35
Identities = 69/150 (46%), Positives = 92/150 (61%), Gaps = 4/150 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPP 58
Y+E +IHRD+AARNCL+ G +VK+ADFG+A+ + D Y G PIKW PP
Sbjct: 1009 YMEEARFIHRDIAARNCLLTSKGPGRIVKIADFGMAKDIYRSDYYRKGGKAMLPIKWMPP 1068
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E F++K+DVWAFGVL+WE+ + G +PY TN E + V G LEKP GC + I
Sbjct: 1069 ESFLDGIFTTKTDVWAFGVLLWEIMSFGYIPYTGCTNREAMTMVTLGGRLEKPAGCPDPI 1128
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQ 148
Y +M CW PE+RPSF + E++ Q
Sbjct: 1129 YGLMTRCWHPRPEDRPSFATIVERIGYCLQ 1158
>UniRef50_Q4SK07 Cluster: Tyrosine-protein kinase receptor; n=2;
Tetraodontidae|Rep: Tyrosine-protein kinase receptor -
Tetraodon nigroviridis (Green puffer)
Length = 1084
Score = 147 bits (357), Expect = 8e-35
Identities = 64/145 (44%), Positives = 91/145 (62%), Gaps = 4/145 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPP 58
YLE + +IHRD+AARNCL+ G V K+ DFG+AR + Y GG P+KW PP
Sbjct: 622 YLEENQFIHRDIAARNCLLTCKGPGRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPP 681
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E F+SK+D W+FGVL+WE+F+ G +PY +N EV++ V G ++ PK C +
Sbjct: 682 EAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSRSNQEVLEFVTNGGRMDPPKNCPGPV 741
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y +M CW H PE+RP+F + E++
Sbjct: 742 YRIMTQCWQHQPEDRPNFSTILERI 766
>UniRef50_Q17C76 Cluster: Focal adhesion kinase; n=2; Culicidae|Rep:
Focal adhesion kinase - Aedes aegypti (Yellowfever
mosquito)
Length = 1092
Score = 147 bits (357), Expect = 8e-35
Identities = 62/143 (43%), Positives = 91/143 (63%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
++YLE ++HRD+AARN LV +K+ADFGL+R+V D Y +S PIKW PE
Sbjct: 568 LSYLESKKFVHRDIAARNVLVSSPTCIKLADFGLSRWVEDQSYYTSTKGMLPIKWMAPES 627
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+NF RF++ SDVW FGV WE+ G P+ + N +V+ K++ G+ L P C +Y+
Sbjct: 628 INFRRFTTASDVWMFGVCTWEILMLGVKPFQGIKNCDVIGKLENGERLPLPPNCPPRLYS 687
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+M CW + P +RP+F+ +KE L
Sbjct: 688 LMSQCWSYEPHKRPNFKNIKEVL 710
>UniRef50_Q8JFV0 Cluster: Tyrosine-protein kinase receptor; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase receptor -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1161
Score = 147 bits (356), Expect = 1e-34
Identities = 65/150 (43%), Positives = 93/150 (62%), Gaps = 4/150 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPP 58
YLE +++IHRD+AARNCL+ G + V K+ DFG+AR + Y GG P+KW PP
Sbjct: 689 YLEENHFIHRDIAARNCLLTCPGPDRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPP 748
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E F+ K+D W+FGVL+WE+F+ G +PY TN EV++ V G ++ PK C +
Sbjct: 749 EAFLEGIFTCKTDTWSFGVLLWEIFSLGYMPYPCKTNQEVLEFVTGGGRMDPPKSCPGPV 808
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQ 148
Y +M CW H PE RP+F + E++ +Q
Sbjct: 809 YRIMTQCWQHCPEHRPNFTTILERINYCTQ 838
>UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga
ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata
Length = 468
Score = 147 bits (356), Expect = 1e-34
Identities = 70/147 (47%), Positives = 93/147 (63%), Gaps = 4/147 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE ++HRDLAARN L+ D+ V KVADFGLA+ D Q + K PIKW PE
Sbjct: 323 MEYLEEQKFVHRDLAARNILLSDDGVAKVADFGLAK---DSQLGVTDIGKLPIKWTAPEA 379
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+ +SKSDVW+FGV++WE+F G+ PY R+ EVVD V +G +E P C E+Y+
Sbjct: 380 IRLKVSTSKSDVWSFGVVLWEIFAFGRAPYPRMGQKEVVDAVVKGYRMECPDTCPKEVYD 439
Query: 121 -VMRACWGHTPEERPSFRVLKEQLAVI 146
+M ACW P +RP+F+ L L+ I
Sbjct: 440 KIMMACWEIDPVKRPTFKTLMRALSSI 466
>UniRef50_A6NNJ8 Cluster: Uncharacterized protein LTK; n=12;
Euarchontoglires|Rep: Uncharacterized protein LTK - Homo
sapiens (Human)
Length = 803
Score = 147 bits (356), Expect = 1e-34
Identities = 68/150 (45%), Positives = 93/150 (62%), Gaps = 4/150 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVLDDQYTSSGGTKF-PIKWAPP 58
YLE +++IHRD+AARNCL+ G V K+ DFG+AR + Y G P+KW PP
Sbjct: 572 YLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRALLPVKWMPP 631
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E F+SK+D W+FGVL+WE+F+ G +PY TN EV+D V G ++ P+GC +
Sbjct: 632 EAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPV 691
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQ 148
Y +M CW H PE RPSF + E+L +Q
Sbjct: 692 YRIMTQCWQHEPELRPSFASILERLQYCTQ 721
>UniRef50_Q98TD0 Cluster: Ephrin receptor; n=6; Amniota|Rep: Ephrin
receptor - Gallus gallus (Chicken)
Length = 969
Score = 147 bits (355), Expect = 1e-34
Identities = 69/152 (45%), Positives = 94/152 (61%), Gaps = 4/152 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL HNY+HRDLAARN LV KV+DFGL+R + +D Y + GG K PI+W
Sbjct: 729 MTYLSEHNYVHRDLAARNILVTRSLQCKVSDFGLSRILENDAEGTYETKGG-KIPIRWTA 787
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + F+S SDVW+FG++MWEV + G PYG +TN EV+ ++ G L P C +
Sbjct: 788 PEAIAHRIFTSASDVWSFGIVMWEVLSFGDKPYGNMTNQEVMKSLEDGYRLPPPVDCPSI 847
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQS 149
+Y +M++CW H RP F+ ++ QL S S
Sbjct: 848 LYELMKSCWSHDRMRRPHFQEIRAQLQHFSSS 879
>UniRef50_Q19238 Cluster: Putative tyrosine-protein kinase F09A5.2;
n=2; Caenorhabditis|Rep: Putative tyrosine-protein
kinase F09A5.2 - Caenorhabditis elegans
Length = 894
Score = 147 bits (355), Expect = 1e-34
Identities = 65/146 (44%), Positives = 95/146 (65%), Gaps = 1/146 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M+YL N+IHRDLAARN L+ KV+DFGL RY+ YT+ GG + PIKW E
Sbjct: 641 MSYLASKNFIHRDLAARNILLTKSLTAKVSDFGLCRYMDSALYTAKGG-RLPIKWMSVEA 699
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L FS+K+DVW+FGVL++E+F+ G VPY + ++++ + G L +P C NEI+N
Sbjct: 700 LKLYEFSTKTDVWSFGVLLFEIFSMGDVPYPTIQQVDMLEHLLAGGRLSQPLKCPNEIFN 759
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVI 146
+M+ CW PE+RP F ++ ++ V+
Sbjct: 760 IMQKCWAEKPEDRPEFNEMRGEITVM 785
>UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23;
Theria|Rep: Tyrosine-protein kinase SYK - Homo sapiens
(Human)
Length = 635
Score = 147 bits (355), Expect = 1e-34
Identities = 64/145 (44%), Positives = 97/145 (66%), Gaps = 2/145 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAPP 58
M YLE N++HRDLAARN L+ ++ K++DFGL++ + D+ Y + K+P+KW P
Sbjct: 482 MKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAP 541
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E +N+ +FSSKSDVW+FGVLMWE F+ G+ PY + SEV +++G+ + P GC E+
Sbjct: 542 ECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREM 601
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y++M CW + E RP F ++ +L
Sbjct: 602 YDLMNLCWTYDVENRPGFAAVELRL 626
>UniRef50_UPI0000D57520 Cluster: PREDICTED: similar to CG8250-PA; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to CG8250-PA
- Tribolium castaneum
Length = 1284
Score = 146 bits (354), Expect = 2e-34
Identities = 70/150 (46%), Positives = 91/150 (60%), Gaps = 4/150 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPP 58
YLE + +IHRD+AARNCL+ G VVK+ADFG++R V D Y G PIKW PP
Sbjct: 943 YLEDNRFIHRDIAARNCLLTTKGPGRVVKIADFGMSRDVYRSDYYRKGGKAMLPIKWMPP 1002
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E F+SK+DVW+FGVL+WE+ + G +PY N EV+ V G L+ P C I
Sbjct: 1003 EAFLDGIFTSKTDVWSFGVLLWEIMSMGYMPYTGCANREVMQLVTSGGRLDPPANCPGPI 1062
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQ 148
Y +M CW TPE+RP+F + E+L Q
Sbjct: 1063 YGIMTQCWHPTPEQRPTFATILERLGYCLQ 1092
>UniRef50_Q9U531 Cluster: Focal adhesion kinase homolog DFak56;
n=15; Sophophora|Rep: Focal adhesion kinase homolog
DFak56 - Drosophila melanogaster (Fruit fly)
Length = 1200
Score = 146 bits (354), Expect = 2e-34
Identities = 65/144 (45%), Positives = 93/144 (64%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGT-KFPIKWAPPE 59
++YLE ++HRD+AARN LV VK+ADFGL+R+V D Y S T PIKW PE
Sbjct: 593 LSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRWVSDQSYYHSTPTVALPIKWMSPE 652
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+NF RF++ SDVW FGV +WE+ G P+ + NS+V+ K++ G+ L P C +Y
Sbjct: 653 SINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKNSDVILKLENGERLPLPPNCPPRLY 712
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
++M CW + P +RP+F+ +KE L
Sbjct: 713 SLMSQCWAYEPLKRPNFKRIKETL 736
>UniRef50_Q7YT64 Cluster: Tyrosine-protein kinase receptor; n=1;
Crassostrea gigas|Rep: Tyrosine-protein kinase receptor
- Crassostrea gigas (Pacific oyster) (Crassostrea
angulata)
Length = 804
Score = 146 bits (354), Expect = 2e-34
Identities = 62/144 (43%), Positives = 96/144 (66%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKF-PIKWAPPE 59
MAYL ++HRDLAARNC+V ++ VK+ADFG+ R + + Y GG P++W PE
Sbjct: 469 MAYLADKKFVHRDLAARNCMVAEDLTVKIADFGMTRDIYETDYYRKGGKALLPVRWMAPE 528
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L F+S SDVW++GV++WE+ T PY L+N EV+ V G+V+EKP+ C + ++
Sbjct: 529 SLKDGIFTSLSDVWSYGVVLWEMATLAAQPYQGLSNEEVLRYVLNGRVMEKPEDCPDRLF 588
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+M+ CW + P++RP+F+ + E+L
Sbjct: 589 ELMQKCWRYRPKQRPTFKEILEEL 612
>UniRef50_Q12866 Cluster: Proto-oncogene tyrosine-protein kinase MER
precursor; n=30; root|Rep: Proto-oncogene
tyrosine-protein kinase MER precursor - Homo sapiens
(Human)
Length = 999
Score = 146 bits (354), Expect = 2e-34
Identities = 67/151 (44%), Positives = 96/151 (63%), Gaps = 1/151 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPPE 59
M YL N++HRDLAARNC++ D+ V VADFGL++ + Y G K P+KW E
Sbjct: 711 MEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIE 770
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++SKSDVWAFGV MWE+ T G PY + N E+ D + G L++P+ C++E+Y
Sbjct: 771 SLADRVYTSKSDVWAFGVTMWEIRTRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELY 830
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQSV 150
+M +CW P +RP+F VL+ QL + +S+
Sbjct: 831 EIMYSCWRTDPLDRPTFSVLRLQLEKLLESL 861
>UniRef50_Q9VBW3 Cluster: Tyrosine kinase receptor Cad96Ca
precursor; n=2; Diptera|Rep: Tyrosine kinase receptor
Cad96Ca precursor - Drosophila melanogaster (Fruit fly)
Length = 773
Score = 146 bits (353), Expect = 2e-34
Identities = 68/144 (47%), Positives = 90/144 (62%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ-YTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN L+ D++ KVADFG AR V+ + Y K PI+W E
Sbjct: 598 MDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGKLPIRWMATE 657
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L FS KSD+W+FG+LMWE+ T G PY ++ ++V+ KV+ G LEKP+ C E+Y
Sbjct: 658 SLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHCRRELY 717
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
N+M CW H P+ERP F + + L
Sbjct: 718 NIMYYCWSHDPQERPLFAEIIQML 741
>UniRef50_Q9XVQ7 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 442
Score = 145 bits (352), Expect = 3e-34
Identities = 70/158 (44%), Positives = 101/158 (63%), Gaps = 5/158 (3%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQY---TSSGGTKFPIKWA 56
M+YL +++HRDLAARNC++ + +VKVADFGLA +LD + Y + +G + P+KW
Sbjct: 252 MSYLAAQHFVHRDLAARNCMISADRIVKVADFGLAVDLLDKESYIDESETGPARLPLKWL 311
Query: 57 PPEVLNFTR-FSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCI 115
PE L R FSS +DVW+FGVLMWE+ T PYG ++N++V ++ G L +P C
Sbjct: 312 APESLRDRRVFSSATDVWSFGVLMWELLTRAASPYGEVSNTKVRHYLETGMRLPQPTHCP 371
Query: 116 NEIYNVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
+ IY++M+ CW TPE+RP F L +L + Q D
Sbjct: 372 DIIYDLMQCCWRSTPEDRPDFVFLSHRLRALLQENTPD 409
>UniRef50_Q52V39 Cluster: Tyrosine-protein kinase receptor; n=2;
Branchiostoma floridae|Rep: Tyrosine-protein kinase
receptor - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 797
Score = 145 bits (352), Expect = 3e-34
Identities = 59/142 (41%), Positives = 95/142 (66%), Gaps = 1/142 (0%)
Query: 3 YLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPPEVL 61
Y+ +++HRDLA RNCLVGD+ VVK+ DFG++R + Y GG T P++W PPE +
Sbjct: 640 YMASQHFVHRDLATRNCLVGDKLVVKIGDFGMSRDIYSTDYYRVGGHTMLPVRWMPPESV 699
Query: 62 NFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYNV 121
+ +F+ +SD+W+FGV++WE+FT GK P+ L N EV++ + G++L P+GC + +
Sbjct: 700 LYRKFTIESDIWSFGVVLWEIFTFGKQPWYELANHEVIECITSGRLLGCPRGCPRNVRAL 759
Query: 122 MRACWGHTPEERPSFRVLKEQL 143
M CW TP +R + + + ++L
Sbjct: 760 MLGCWKKTPAQRTNIQDIHKKL 781
>UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11;
Mammalia|Rep: Tyrosine-protein kinase 6 - Homo sapiens
(Human)
Length = 451
Score = 145 bits (352), Expect = 3e-34
Identities = 67/144 (46%), Positives = 92/144 (63%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE NYIHRDLAARN LVG+ + KV DFGLAR + +D Y S P KW PE
Sbjct: 300 MCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHN-IPYKWTAPEA 358
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L+ +S+KSDVW+FG+L+ E+F+ G+VPY ++N E +V G + P C ++
Sbjct: 359 LSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHK 418
Query: 121 VMRACWGHTPEERPSFRVLKEQLA 144
+M CW PE+RP F+ L+E+L+
Sbjct: 419 LMLTCWCRDPEQRPCFKALRERLS 442
>UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein
kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated
tyrosine-protein kinase - Homo sapiens (Human)
Length = 507
Score = 145 bits (352), Expect = 3e-34
Identities = 66/144 (45%), Positives = 94/144 (65%), Gaps = 4/144 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE +HRDLAARN LV ++ V KV+DFGLA+ + ++ P+KW PE
Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKA----ERKGLDSSRLPVKWTAPEA 395
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L +F+SKSDVW+FGVL+WEVF+ G+ PY +++ EV + V++G +E P+GC ++
Sbjct: 396 LKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHV 455
Query: 121 VMRACWGHTPEERPSFRVLKEQLA 144
+M +CW P RP FR L E+LA
Sbjct: 456 LMSSCWEAEPARRPPFRKLAEKLA 479
>UniRef50_UPI0000E257E1 Cluster: PREDICTED: similar to tyrosine
kinase; n=1; Pan troglodytes|Rep: PREDICTED: similar to
tyrosine kinase - Pan troglodytes
Length = 299
Score = 145 bits (351), Expect = 4e-34
Identities = 67/144 (46%), Positives = 92/144 (63%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE NYIHRDLAARN LVG+ + KV DFGLAR + +D Y S P KW PE
Sbjct: 148 MCYLELQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHN-IPYKWTAPEA 206
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L+ +S+KSDVW+FG+L+ E+F+ G+VPY ++N E +V G + P C ++
Sbjct: 207 LSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHK 266
Query: 121 VMRACWGHTPEERPSFRVLKEQLA 144
+M CW PE+RP F+ L+E+L+
Sbjct: 267 LMLTCWCRDPEQRPCFKALRERLS 290
>UniRef50_Q4RJ67 Cluster: Chromosome 1 SCAF15039, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 1
SCAF15039, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 978
Score = 145 bits (351), Expect = 4e-34
Identities = 65/149 (43%), Positives = 98/149 (65%), Gaps = 2/149 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YL +IHRDLAARN LVGD V K+ADFGL+R ++ Y + P++W E
Sbjct: 807 MHYLSDKQFIHRDLAARNVLVGDNLVAKIADFGLSRG--EEVYVKKTMGRLPVRWMAIES 864
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
LN++ +++KSDVW+FGVL+WE+ + G PY +T +E+ +K+ +G +EKPK C +E+Y
Sbjct: 865 LNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGFRMEKPKNCDDEVYE 924
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQS 149
+M+ CW P ERP F + QL+ + ++
Sbjct: 925 LMKQCWRDRPYERPPFSQISVQLSRMQEA 953
>UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 743
Score = 145 bits (351), Expect = 4e-34
Identities = 67/142 (47%), Positives = 92/142 (64%), Gaps = 3/142 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV--LDDQYTSSGGTKFPIKWAPP 58
M YLE ++HRDLAARN LV VK++DFGL+R V D Y +S G ++P+KW P
Sbjct: 578 MMYLETKRFVHRDLAARNILVQSMKQVKISDFGLSRAVGANSDYYKASQGGRWPVKWYAP 637
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQR-GQVLEKPKGCINE 117
E +NF FS SDVW++G+ +WE+F+ G PYG +T +EV+D+V+ LE P+ C +
Sbjct: 638 ESINFGTFSHASDVWSYGITLWEMFSFGDAPYGDMTGAEVLDRVENLNYRLECPRDCPSS 697
Query: 118 IYNVMRACWGHTPEERPSFRVL 139
IY +M CW P ERP+F L
Sbjct: 698 IYELMLRCWSLEPNERPTFAQL 719
>UniRef50_Q8IXC7 Cluster: Isoform of FGFR2; n=23; Euteleostomi|Rep:
Isoform of FGFR2 - Homo sapiens (Human)
Length = 709
Score = 145 bits (351), Expect = 4e-34
Identities = 67/144 (46%), Positives = 91/144 (63%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN LV + NV+K+ADFGLAR + + D Y + + P+KW PE
Sbjct: 502 MEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPE 561
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++ +SDVW+FGVLMWE+FT G PY + E+ ++ G ++KP C NE+Y
Sbjct: 562 ALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELY 621
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+MR CW P +RP+F+ L E L
Sbjct: 622 MMMRDCWHAVPSQRPTFKQLVEDL 645
>UniRef50_Q4SQX3 Cluster: Chromosome 11 SCAF14528, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF14528, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 780
Score = 144 bits (350), Expect = 6e-34
Identities = 70/139 (50%), Positives = 88/139 (63%), Gaps = 4/139 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL YIHRDLAARN LV V KV+DFGL+R + DD YT+SGG K PI+W
Sbjct: 528 MTYLSDLGYIHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPDAAYTTSGG-KIPIRWTA 586
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + F +FSS SDVW++GV+MWEV + G+ PY LTN +V+ V+ G L P GC
Sbjct: 587 PEAITFRKFSSSSDVWSYGVVMWEVTSYGERPYWNLTNRDVIKSVEEGYRLPAPMGCPAA 646
Query: 118 IYNVMRACWGHTPEERPSF 136
++ +M CW ERP F
Sbjct: 647 LHTLMLDCWQKDRNERPRF 665
>UniRef50_Q25410 Cluster: Putative molluscan insulin-related
peptide(s) receptor precursor (EC 2.7.10.1) [Contains:
Putative molluscan insulin-related peptide(s) receptor
alpha chain; Putative molluscan insulin-related
peptide(s) receptor beta chain]; n=2; Coelomata|Rep:
Putative molluscan insulin-related peptide(s) receptor
precursor (EC 2.7.10.1) [Contains: Putative molluscan
insulin-related peptide(s) receptor alpha chain; Putative
molluscan insulin-related peptide(s) receptor beta chain]
- Lymnaea stagnalis (Great pond snail)
Length = 1607
Score = 144 bits (350), Expect = 6e-34
Identities = 63/144 (43%), Positives = 90/144 (62%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGT-KFPIKWAPPE 59
MAYL ++HRDLAARNC+V +E VK+ DFG+ R + + Y GG P++W PE
Sbjct: 1161 MAYLADKKFVHRDLAARNCMVSEERTVKIGDFGMTRDIYETDYYRKGGKGMLPVRWMAPE 1220
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L F+S SDVW++GV+MWE+ T PY L+N EVV + G ++E P+ C NE+
Sbjct: 1221 SLKDGVFTSLSDVWSYGVVMWEMVTLAAQPYQGLSNEEVVKFISDGYIMELPENCPNEMA 1280
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+M+ CW P +RP+F+ + E L
Sbjct: 1281 YLMQHCWAKKPNQRPTFKAIIEYL 1304
>UniRef50_Q16288 Cluster: NT-3 growth factor receptor precursor;
n=49; Euteleostomi|Rep: NT-3 growth factor receptor
precursor - Homo sapiens (Human)
Length = 839
Score = 144 bits (349), Expect = 7e-34
Identities = 64/164 (39%), Positives = 104/164 (63%), Gaps = 15/164 (9%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTS--------------- 45
M YL +++HRDLA RNCLVG +VK+ DFG++R V Y
Sbjct: 667 MVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEV 726
Query: 46 SGGTKFPIKWAPPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRG 105
G T PI+W PPE + + +F+++SDVW+FGV++WE+FT GK P+ +L+N+EV++ + +G
Sbjct: 727 GGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQG 786
Query: 106 QVLEKPKGCINEIYNVMRACWGHTPEERPSFRVLKEQLAVISQS 149
+VLE+P+ C E+Y+VM CW P++R + + + + L + ++
Sbjct: 787 RVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKA 830
>UniRef50_Q3TJ05 Cluster: 14 days pregnant adult female placenta
cDNA, RIKEN full-length enriched library,
clone:I530025O09 product:fibroblast growth factor
receptor 1, full insert sequence; n=18; Eumetazoa|Rep:
14 days pregnant adult female placenta cDNA, RIKEN
full-length enriched library, clone:I530025O09
product:fibroblast growth factor receptor 1, full insert
sequence - Mus musculus (Mouse)
Length = 386
Score = 144 bits (348), Expect = 1e-33
Identities = 66/144 (45%), Positives = 91/144 (63%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN LV ++NV+K+ADFGLAR + D Y + + P+KW PE
Sbjct: 175 MEYLASKKCIHRDLAARNALVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPE 234
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++ +SDVW+FGVL+WE+FT G PY + E+ ++ G ++KP C NE+Y
Sbjct: 235 ALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELY 294
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+MR CW P +RP+F+ L E L
Sbjct: 295 MMMRDCWHAVPSQRPTFKQLVEDL 318
>UniRef50_Q9VZI2 Cluster: CG14992-PA; n=3; Sophophora|Rep:
CG14992-PA - Drosophila melanogaster (Fruit fly)
Length = 1073
Score = 144 bits (348), Expect = 1e-33
Identities = 69/154 (44%), Positives = 94/154 (61%), Gaps = 3/154 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL--DDQYTSSGGTKFPIKWAPP 58
MAYLE+ ++HRDLA RN L+ N +K+ DFGL R + DD Y S K P W P
Sbjct: 238 MAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAP 297
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQR-GQVLEKPKGCINE 117
E L F +FS SD W FGV +WE+F+ G+ P+ L S+++ K+ R G+ L +P C +
Sbjct: 298 ESLRFRQFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPD 357
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQSVL 151
+Y +M CW TP ERP+F LKE LA +S V+
Sbjct: 358 VYAMMLQCWDKTPAERPTFAALKEYLASMSPPVM 391
>UniRef50_Q96HF4 Cluster: EPHA2 protein; n=3; Amniota|Rep: EPHA2
protein - Homo sapiens (Human)
Length = 253
Score = 144 bits (348), Expect = 1e-33
Identities = 68/139 (48%), Positives = 88/139 (63%), Gaps = 4/139 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL NY+HRDLAARN LV V KV+DFGL+R + DD YT+SGG K PI+W
Sbjct: 4 MKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGG-KIPIRWTA 62
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE +++ +F+S SDVW+FG++MWEV T G+ PY L+N EV+ + G L P C +
Sbjct: 63 PEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSA 122
Query: 118 IYNVMRACWGHTPEERPSF 136
IY +M CW RP F
Sbjct: 123 IYQLMMQCWQQERARRPKF 141
>UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hydra
vulgaris|Rep: Tyrosine-protein kinase HTK16 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 757
Score = 144 bits (348), Expect = 1e-33
Identities = 63/141 (44%), Positives = 94/141 (66%), Gaps = 2/141 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL--DDQYTSSGGTKFPIKWAPP 58
M YLE ++HRDLAARN L+ ++ VK++DFGL+R V D Y + G ++P++W P
Sbjct: 596 MMYLELKRFVHRDLAARNILLANKKQVKISDFGLSRAVGTGSDYYQAKQGGRWPVRWYAP 655
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E +N+ FS+KSDVW++G+ +WE+FT G +PYG +T +EVV ++ LEKP C
Sbjct: 656 ESINYGTFSTKSDVWSYGITLWEMFTFGDLPYGEMTGNEVVSFLEHCGRLEKPDECPIHT 715
Query: 119 YNVMRACWGHTPEERPSFRVL 139
Y++M +CW P +RP+F L
Sbjct: 716 YSIMLSCWHIDPNKRPTFNEL 736
>UniRef50_P29317 Cluster: Ephrin type-A receptor 2 precursor; n=32;
Euteleostomi|Rep: Ephrin type-A receptor 2 precursor -
Homo sapiens (Human)
Length = 976
Score = 144 bits (348), Expect = 1e-33
Identities = 68/139 (48%), Positives = 88/139 (63%), Gaps = 4/139 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL NY+HRDLAARN LV V KV+DFGL+R + DD YT+SGG K PI+W
Sbjct: 727 MKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGG-KIPIRWTA 785
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE +++ +F+S SDVW+FG++MWEV T G+ PY L+N EV+ + G L P C +
Sbjct: 786 PEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSA 845
Query: 118 IYNVMRACWGHTPEERPSF 136
IY +M CW RP F
Sbjct: 846 IYQLMMQCWQQERARRPKF 864
>UniRef50_UPI0000F2052A Cluster: PREDICTED: similar to anaplastic
lymphoma kinase (Ki-1),; n=1; Danio rerio|Rep: PREDICTED:
similar to anaplastic lymphoma kinase (Ki-1), - Danio
rerio
Length = 1387
Score = 143 bits (347), Expect = 1e-33
Identities = 63/145 (43%), Positives = 90/145 (62%), Gaps = 4/145 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPP 58
YLE + +IHRD+AARNCL+ G V K+ DFG+AR + Y GG P+KW PP
Sbjct: 918 YLEENQFIHRDIAARNCLLTCKGPGRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPP 977
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E F+SK+D W+FGVL+WE+F+ G +PY +N EV++ V G ++ PK C +
Sbjct: 978 EAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSRSNQEVLEFVTNGGRMDPPKNCPGPV 1037
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y +M W H PE+RP+F + E++
Sbjct: 1038 YRIMTQSWQHQPEDRPNFSTILERI 1062
>UniRef50_Q9BKL8 Cluster: Tyrosine-protein kinase receptor; n=2;
Eumetazoa|Rep: Tyrosine-protein kinase receptor -
Aplysia californica (California sea hare)
Length = 1145
Score = 143 bits (347), Expect = 1e-33
Identities = 64/144 (44%), Positives = 91/144 (63%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL H+++HRDLAARN LV D VK++DFGL+R V D Y + P++W PPE
Sbjct: 703 MEYLASHHFVHRDLAARNILVADGLTVKISDFGLSRDVYSSDYYRVQSKSLLPVRWMPPE 762
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + +F++ SDVWAFGV++WEVF+ G PY +N EV++ ++ Q+L P+ C IY
Sbjct: 763 AILYGKFTTDSDVWAFGVVLWEVFSYGLQPYYGFSNQEVIEMIRSRQILGCPEECPARIY 822
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+M CW P RP FR + +L
Sbjct: 823 GLMVECWHEMPARRPPFREIHTRL 846
>UniRef50_P11362 Cluster: Basic fibroblast growth factor receptor 1
precursor; n=310; Euteleostomi|Rep: Basic fibroblast
growth factor receptor 1 precursor - Homo sapiens
(Human)
Length = 822
Score = 143 bits (347), Expect = 1e-33
Identities = 66/144 (45%), Positives = 91/144 (63%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN LV ++NV+K+ADFGLAR + D Y + + P+KW PE
Sbjct: 611 MEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPE 670
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++ +SDVW+FGVL+WE+FT G PY + E+ ++ G ++KP C NE+Y
Sbjct: 671 ALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELY 730
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+MR CW P +RP+F+ L E L
Sbjct: 731 MMMRDCWHAVPSQRPTFKQLVEDL 754
>UniRef50_O76997 Cluster: Putative neurotrophin receptor LTRK 1
precursor; n=2; Lymnaea stagnalis|Rep: Putative
neurotrophin receptor LTRK 1 precursor - Lymnaea
stagnalis (Great pond snail)
Length = 794
Score = 143 bits (346), Expect = 2e-33
Identities = 62/145 (42%), Positives = 96/145 (66%), Gaps = 2/145 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL +++HRDLA RNCLVG + VVK+ DFG++R V D Y G P++W PPE
Sbjct: 635 MEYLALQHFVHRDLATRNCLVGCDLVVKLGDFGMSRDVYTTDYYRVEGTAMLPVRWMPPE 694
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEK-PKGCINEI 118
+ + F+++SDVW+FGV +WEVFT GK P+ +NSEV++ ++ + L++ P+ C + +
Sbjct: 695 SIIYRTFTTESDVWSFGVTLWEVFTYGKQPWFEYSNSEVIEHIKNSRTLKRPPRTCTDGV 754
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y VM+ CW P++R + + + E L
Sbjct: 755 YRVMQGCWKPNPQDRLTMKDIAELL 779
>UniRef50_Q6DTW4 Cluster: Tyrosine kinase receptor ron; n=6;
Eumetazoa|Rep: Tyrosine kinase receptor ron - Canis
familiaris (Dog)
Length = 998
Score = 142 bits (345), Expect = 2e-33
Identities = 66/156 (42%), Positives = 97/156 (62%), Gaps = 3/156 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTS---SGGTKFPIKWAP 57
M YL ++HRDLAARNC++ + VKVADFGLAR +LD +Y S + P+KW
Sbjct: 794 MEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDKEYYSVRQHRHARLPVKWMA 853
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
E L RF++KSDVW+FGVL+WE+ T G PY + +++ + +G+ L +P+ C N
Sbjct: 854 LESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYPHIDPFDLIQFLAQGRRLPQPEYCPNS 913
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
+Y VM+ CW P RP+F L E++ ++ +L D
Sbjct: 914 LYMVMQRCWAVDPAVRPTFTALVEEVEHVAARLLGD 949
>UniRef50_Q170Z1 Cluster: Tyrosine-protein kinase receptor; n=1; Aedes
aegypti|Rep: Tyrosine-protein kinase receptor - Aedes
aegypti (Yellowfever mosquito)
Length = 2073
Score = 142 bits (345), Expect = 2e-33
Identities = 66/140 (47%), Positives = 90/140 (64%), Gaps = 5/140 (3%)
Query: 3 YLERHNYIHRDLAARNCLVGD----ENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAP 57
YLE +++HRDLA RNCLV E VVK+ DFGLAR + +D Y G P++W
Sbjct: 1934 YLEEMHFVHRDLACRNCLVSSMDPRERVVKIGDFGLARDIYKNDYYRKEGEGLLPVRWMS 1993
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE L F+S+SD+WAFGVL+WE+ T G+ PY N EV+ V+ G L +P+ C E
Sbjct: 1994 PESLVDGVFTSQSDIWAFGVLLWEIMTLGQQPYPARNNVEVLHYVRDGGRLTRPQDCPEE 2053
Query: 118 IYNVMRACWGHTPEERPSFR 137
+Y +M CW ++PE+RP+FR
Sbjct: 2054 LYQLMLKCWSYSPEDRPTFR 2073
>UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CSK;
n=1; Hydra vulgaris|Rep: Non-receptor protein-tyrosine
kinase CSK - Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 467
Score = 142 bits (345), Expect = 2e-33
Identities = 68/143 (47%), Positives = 92/143 (64%), Gaps = 4/143 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YLE N IHRDLAARN L+ DE KV+DFGLA+ V +Q +SG KFP+KW PE
Sbjct: 320 MRYLEEKNIIHRDLAARNVLLSDELCAKVSDFGLAKDV--EQELASG--KFPVKWTAPEA 375
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+ FS+KSDVW+FG+L+WE+F+ G+ PY R E++ K++ +E P+ C +Y
Sbjct: 376 IELKIFSTKSDVWSFGILLWEIFSFGRNPYPREPLDELLTKIKSNYRMECPEKCPPFVYQ 435
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+M CW P RPSF+ L +L
Sbjct: 436 LMLKCWDADPSRRPSFKQLHNEL 458
>UniRef50_O17391 Cluster: Protein kinase protein 9, isoform b; n=3;
Caenorhabditis|Rep: Protein kinase protein 9, isoform b
- Caenorhabditis elegans
Length = 615
Score = 142 bits (345), Expect = 2e-33
Identities = 67/148 (45%), Positives = 95/148 (64%), Gaps = 4/148 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
+ YL IHRD+AARN LV N K+ DFGL R YT+ GG + P+KW PE
Sbjct: 441 LEYLNNIGCIHRDIAARNVLVDSANTCKIGDFGLCRLTDSLLYTARGG-RLPLKWMAPES 499
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L +S KSDVW++GVL+WE+F+ G+VPYG + +E++ + G+ L KP+ C EIY+
Sbjct: 500 LATYEYSYKSDVWSYGVLLWELFSLGEVPYGEVQTTELLQTHRSGKRLLKPEWCPEEIYD 559
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQ 148
VMR CW P++RP+F ++ AV++Q
Sbjct: 560 VMRLCWQELPDDRPAF---QQTCAVLAQ 584
>UniRef50_P08922 Cluster: Proto-oncogene tyrosine-protein kinase ROS
precursor; n=20; Eumetazoa|Rep: Proto-oncogene
tyrosine-protein kinase ROS precursor - Homo sapiens
(Human)
Length = 2347
Score = 142 bits (345), Expect = 2e-33
Identities = 65/147 (44%), Positives = 98/147 (66%), Gaps = 6/147 (4%)
Query: 3 YLERHNYIHRDLAARNCLVGDEN-----VVKVADFGLARYVL-DDQYTSSGGTKFPIKWA 56
YLER ++IHRDLAARNCLV ++ +VK+ DFGLAR + +D Y G P++W
Sbjct: 2069 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWM 2128
Query: 57 PPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCIN 116
PE L F+++SDVW+FG+L+WE+ T G PY +N +V++ VQ G LE P+ C +
Sbjct: 2129 APESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPD 2188
Query: 117 EIYNVMRACWGHTPEERPSFRVLKEQL 143
+++N+M CW P++RP+F +++QL
Sbjct: 2189 DLWNLMTQCWAQEPDQRPTFHRIQDQL 2215
>UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12;
Eumetazoa|Rep: Tyrosine-protein kinase Fps85D -
Drosophila melanogaster (Fruit fly)
Length = 1325
Score = 142 bits (345), Expect = 2e-33
Identities = 64/137 (46%), Positives = 88/137 (64%), Gaps = 3/137 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK-FPIKWAPPE 59
M YLE N IHRDLAARNCLV E+ VK++DFG++R +++Y S G K P+KW PE
Sbjct: 1173 MRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSRE--EEEYIVSDGMKQIPVKWTAPE 1230
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
LNF +++S DVW++G+LMWE+F+ G PY +TNS +++ G + PK E+Y
Sbjct: 1231 ALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMY 1290
Query: 120 NVMRACWGHTPEERPSF 136
+M CW E RP F
Sbjct: 1291 RLMLQCWAADAESRPHF 1307
>UniRef50_UPI00015B4CAE Cluster: PREDICTED: similar to
ENSANGP00000019144; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000019144 - Nasonia
vitripennis
Length = 1220
Score = 142 bits (344), Expect = 3e-33
Identities = 65/147 (44%), Positives = 91/147 (61%), Gaps = 3/147 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQY---TSSGGTKFPIKWAP 57
M YL IHRDLAARN LV + K+ADFG++R+ +D T G PI+W
Sbjct: 1051 MEYLASKKIIHRDLAARNVLVDHNKLCKIADFGMSRFANEDGEVIETRHGRNALPIRWMA 1110
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE L ++ F++K+DVW+FG+LMWE+ T G PY +T EV+ VQ G LE+P C +E
Sbjct: 1111 PESLIYSLFTTKTDVWSFGILMWEIVTLGSTPYPDMTAREVMRSVQSGYRLERPSHCRSE 1170
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLA 144
++ V+ CW P+ RP F++L+ LA
Sbjct: 1171 LFRVIARCWHADPDRRPEFQLLRRDLA 1197
>UniRef50_UPI0000E4736E Cluster: PREDICTED: similar to src-family
protein tyrosine kinase; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to src-family protein
tyrosine kinase - Strongylocentrotus purpuratus
Length = 387
Score = 142 bits (344), Expect = 3e-33
Identities = 65/141 (46%), Positives = 86/141 (60%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YL N +HRDLAARN LVG NVVK+ADFG A+ + D Y G K P+KW PE
Sbjct: 234 MDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGRAQLMEKDVYVGEEGAKLPLKWTAPEA 293
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+ RF+ KSDVW+FG+LM E+ T G PY ++ EV KV G + K C + +Y
Sbjct: 294 VLHGRFTIKSDVWSFGILMTEMVTFGGYPYKKMRTREVTKKVANGYRMPKMDHCTDSLYM 353
Query: 121 VMRACWGHTPEERPSFRVLKE 141
+M CW P++RP+F+ L +
Sbjct: 354 IMLKCWHKDPQQRPTFKYLHD 374
>UniRef50_Q9U8U9 Cluster: PDGFR-like; n=1; Eptatretus burgeri|Rep:
PDGFR-like - Eptatretus burgeri (Inshore hagfish)
Length = 401
Score = 142 bits (344), Expect = 3e-33
Identities = 64/145 (44%), Positives = 95/145 (65%), Gaps = 2/145 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV-LDDQYTSSGGTKFPIKWAPPE 59
M +L HN +HRDLAARN L+G+E +VK+ DFGLAR + +D Y S G T P+KW PE
Sbjct: 167 MEFLASHNCVHRDLAARNVLLGNERMVKICDFGLARDLSIDANYISKGTTFLPVKWMAPE 226
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPY-GRLTNSEVVDKVQRGQVLEKPKGCINEI 118
+ + ++ +SDVW++GVL+WE+FT G+ PY G +S +++ G +EKPK + I
Sbjct: 227 SIFHSLYTPQSDVWSYGVLLWEIFTLGESPYPGMTVDSNFYTRLREGYRMEKPKLSSDNI 286
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y +M CW ++RP+F L E++
Sbjct: 287 YQLMGKCWNSNADKRPTFTELAEKI 311
>UniRef50_Q7Q5T3 Cluster: Tyrosine-protein kinase receptor; n=3;
Endopterygota|Rep: Tyrosine-protein kinase receptor -
Anopheles gambiae str. PEST
Length = 646
Score = 142 bits (344), Expect = 3e-33
Identities = 61/150 (40%), Positives = 97/150 (64%), Gaps = 1/150 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL H+Y+HRDLAARNCLVGD VK++DFGL+R + D Y + P++W P E
Sbjct: 491 MEYLASHHYVHRDLAARNCLVGDNLTVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSE 550
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + +F+++SDVW+FGV++WE+++ G PY +N EV++ V+ Q+L P+ C + +Y
Sbjct: 551 SILYGKFTTESDVWSFGVVLWEIYSYGLQPYYGYSNQEVINMVRARQLLPCPESCPSAVY 610
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQS 149
++M CW RP+F + +L + Q+
Sbjct: 611 SLMVECWHEQAVRRPTFPEIGHRLKIWYQA 640
>UniRef50_A7RGW8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 337
Score = 142 bits (344), Expect = 3e-33
Identities = 65/145 (44%), Positives = 94/145 (64%), Gaps = 2/145 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDD-QYTSSGGT-KFPIKWAPP 58
M YL + ++HRDLAARN L+ ++N+VK++DFGL R V + +Y T K P+KW P
Sbjct: 151 MEYLSQKMFVHRDLAARNILICEDNLVKISDFGLTRDVYESSEYHKMHNTGKLPLKWMAP 210
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E + ++KSDVWAFGV++WE+ T G PY + E K++ G +EKP C E+
Sbjct: 211 EAIFQNVHTTKSDVWAFGVVLWEIVTLGGSPYPGQSGKEFYKKLKNGYRMEKPDMCSPEL 270
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y +MR+CW +PE+RP+F L+ QL
Sbjct: 271 YAMMRSCWASSPEDRPTFTKLRNQL 295
>UniRef50_Q59F30 Cluster: Fibroblast growth factor receptor 4
variant; n=28; Eumetazoa|Rep: Fibroblast growth factor
receptor 4 variant - Homo sapiens (Human)
Length = 1034
Score = 142 bits (344), Expect = 3e-33
Identities = 65/144 (45%), Positives = 91/144 (63%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YLE IHRDLAARN LV ++NV+K+ADFGLAR V D Y + + P+KW PE
Sbjct: 832 MQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPE 891
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++ +SDVW+FG+L+WE+FT G PY + E+ ++ G +++P C E+Y
Sbjct: 892 ALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELY 951
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+MR CW P +RP+F+ L E L
Sbjct: 952 GLMRECWHAAPSQRPTFKQLVEAL 975
>UniRef50_Q06418 Cluster: Tyrosine-protein kinase receptor TYRO3
precursor; n=30; Tetrapoda|Rep: Tyrosine-protein kinase
receptor TYRO3 precursor - Homo sapiens (Human)
Length = 890
Score = 142 bits (343), Expect = 4e-33
Identities = 62/144 (43%), Positives = 92/144 (63%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSG-GTKFPIKWAPPE 59
M YL N+IHRDLAARNC++ ++ V VADFGL+R + Y G +K P+KW E
Sbjct: 643 MEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALE 702
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++ +SDVWAFGV MWE+ T G+ PY + N+E+ + + G L++P C+ ++Y
Sbjct: 703 SLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPPECMEDVY 762
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
++M CW P++RPSF L+ +L
Sbjct: 763 DLMYQCWSADPKQRPSFTCLRMEL 786
>UniRef50_P79950 Cluster: Tyrosine kinase receptor; n=3; Xenopus|Rep:
Tyrosine kinase receptor - Xenopus laevis (African clawed
frog)
Length = 1369
Score = 141 bits (342), Expect = 5e-33
Identities = 67/156 (42%), Positives = 96/156 (61%), Gaps = 3/156 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTS---SGGTKFPIKWAP 57
M YL ++HRDLAARNC++ + VKVADFGLAR V D +Y S + P+KW
Sbjct: 1171 MEYLANRKFVHRDLAARNCMLDESFHVKVADFGLARDVFDKEYYSVRRHKNARLPVKWMA 1230
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
E L +F++KSDVW+FGVL+WE+ T G PY + ++ + RG+ L +P+ C N
Sbjct: 1231 MESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVDAYDITRYLFRGRRLAQPEYCPNP 1290
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
+Y++M +CW P ERP+F L + +IS S+ D
Sbjct: 1291 LYSLMLSCWNPQPVERPTFTQLVSDMELISNSLSGD 1326
>UniRef50_Q008W6 Cluster: Gamma-carboxyglutamic acid protein 1; n=2;
Ascidiacea|Rep: Gamma-carboxyglutamic acid protein 1 -
Ciona intestinalis (Transparent sea squirt)
Length = 556
Score = 141 bits (342), Expect = 5e-33
Identities = 63/154 (40%), Positives = 94/154 (61%), Gaps = 5/154 (3%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL ++HRDLAARNC+V VKVADFGL+R + D D Y SS T+ P+KW PPE
Sbjct: 291 MEYLAEKKFVHRDLAARNCMVDKNWCVKVADFGLSRDLFDRDYYRSSVKTQLPLKWMPPE 350
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + R+ KSDVW++G++ WE+ T G +PY + ++ + G +E+P+ C +++Y
Sbjct: 351 SIKYGRYGEKSDVWSYGIVCWEIMTRGAIPYPTVQAVAILQYLSEGNRMERPECCPHKLY 410
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
M CW E RP+F E+L I+ ++ D
Sbjct: 411 KTMEKCWLDDTERRPTF----EELVTITTKIVRD 440
>UniRef50_P29322 Cluster: Ephrin type-A receptor 8 precursor; n=22;
Euteleostomi|Rep: Ephrin type-A receptor 8 precursor -
Homo sapiens (Human)
Length = 1005
Score = 141 bits (342), Expect = 5e-33
Identities = 69/152 (45%), Positives = 92/152 (60%), Gaps = 4/152 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL Y+HRDLAARN LV V KV+DFGL+R + DD YT++GG K PI+W
Sbjct: 748 MRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGG-KIPIRWTA 806
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + F FSS SDVW+FGV+MWEV G+ PY +TN +V+ V+ G L P GC +
Sbjct: 807 PEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHA 866
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQS 149
++ +M CW +RP F + L + +S
Sbjct: 867 LHQLMLDCWHKDRAQRPRFSQIVSVLDALIRS 898
>UniRef50_Q9YI66 Cluster: Developmental receptor tyrosine kinase;
n=6; Bilateria|Rep: Developmental receptor tyrosine
kinase - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 874
Score = 141 bits (341), Expect = 7e-33
Identities = 64/147 (43%), Positives = 94/147 (63%), Gaps = 1/147 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPPE 59
M YL N IHRDLAARNC++ + V VADFGL++ + Y G +K P+KW E
Sbjct: 622 MEYLSNKNIIHRDLAARNCMLNENMSVCVADFGLSKKIYSGDYYRQGSVSKLPVKWIALE 681
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++++SDVWAFGV MWE+ T G+ PY + NSE+ + + +G+ L++P C +IY
Sbjct: 682 SLADNVYTTQSDVWAFGVTMWEIMTRGQTPYPGVENSEIYEYLIKGERLKQPPDCPADIY 741
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVI 146
+M +CW P+ RPSF+ L +QL ++
Sbjct: 742 EIMHSCWSPVPKCRPSFQHLIDQLELL 768
>UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 573
Score = 141 bits (341), Expect = 7e-33
Identities = 61/145 (42%), Positives = 92/145 (63%), Gaps = 2/145 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL--DDQYTSSGGTKFPIKWAPP 58
MAYLE ++HRDLAARN LV D++ VK++DFG++R + + Y + ++P+KW P
Sbjct: 399 MAYLEEVRFVHRDLAARNVLVVDDDNVKISDFGMSRAIGAGSEYYKAETAGRWPLKWYAP 458
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E + + +F SKSDVW++GV +WE F+ G PY L +++ ++ Q L+ P+ C I
Sbjct: 459 ECIYYAKFDSKSDVWSYGVTVWEAFSFGAKPYAGLKGQDIMQMLEGNQRLDSPEKCPQPI 518
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y++M CW PE+RPSF L L
Sbjct: 519 YDIMLRCWAWRPEDRPSFSELSSML 543
>UniRef50_Q17LF1 Cluster: Muscle-specific tyrosine kinase receptor;
n=5; Endopterygota|Rep: Muscle-specific tyrosine kinase
receptor - Aedes aegypti (Yellowfever mosquito)
Length = 666
Score = 141 bits (341), Expect = 7e-33
Identities = 61/147 (41%), Positives = 91/147 (61%), Gaps = 1/147 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV-LDDQYTSSGGTKFPIKWAPPE 59
M YL ++HRDLA RNCL+ D VVK+ADFGL+ + L D Y PI+W P E
Sbjct: 510 MVYLSERKFVHRDLATRNCLIDDNMVVKIADFGLSHKIYLQDYYKGDENDAIPIRWMPLE 569
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + +++ +SDVWA+GV +WE+F+ PY +T+ EVV V+ G +L P+ +Y
Sbjct: 570 SILYNKYTIESDVWAYGVCLWEIFSFAMQPYYGMTHEEVVKFVKEGNMLSCPENTPLTVY 629
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVI 146
++MR CW P +RPSF ++ ++L I
Sbjct: 630 DLMRKCWSRKPADRPSFPIIFQKLQQI 656
>UniRef50_P30530 Cluster: Tyrosine-protein kinase receptor UFO
precursor; n=37; Euteleostomi|Rep: Tyrosine-protein
kinase receptor UFO precursor - Homo sapiens (Human)
Length = 887
Score = 141 bits (341), Expect = 7e-33
Identities = 64/144 (44%), Positives = 92/144 (63%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPPE 59
M YL +IHRDLAARNC++ + V VADFGL++ + + Y G K P+KW E
Sbjct: 653 MEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIE 712
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++SKSDVW+FGV MWE+ T G+ PY + NSE+ D +++G L++P C++ +Y
Sbjct: 713 SLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPADCLDGLY 772
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+M CW P++RPSF L+E L
Sbjct: 773 ALMSRCWELNPQDRPSFTELREDL 796
>UniRef50_Q04912 Cluster: Macrophage-stimulating protein receptor
precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CD136
antigen) (CDw136) [Contains: Macrophage- stimulating
protein receptor alpha chain; Macrophage-stimulating
protein receptor beta chain]; n=15; Eutheria|Rep:
Macrophage-stimulating protein receptor precursor (EC
2.7.10.1) (MSP receptor) (p185-Ron) (CD136 antigen)
(CDw136) [Contains: Macrophage- stimulating protein
receptor alpha chain; Macrophage-stimulating protein
receptor beta chain] - Homo sapiens (Human)
Length = 1400
Score = 141 bits (341), Expect = 7e-33
Identities = 67/156 (42%), Positives = 97/156 (62%), Gaps = 3/156 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTS---SGGTKFPIKWAP 57
M YL ++HRDLAARNC++ + VKVADFGLAR +LD +Y S + P+KW
Sbjct: 1196 MEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMA 1255
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
E L RF++KSDVW+FGVL+WE+ T G PY + ++ + +G+ L +P+ C +
Sbjct: 1256 LESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPDS 1315
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
+Y VM+ CW P RP+FRVL ++ I ++L D
Sbjct: 1316 LYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGD 1351
>UniRef50_O02742 Cluster: Activated CDC42 kinase 2; n=13;
Euteleostomi|Rep: Activated CDC42 kinase 2 - Bos taurus
(Bovine)
Length = 747
Score = 141 bits (341), Expect = 7e-33
Identities = 66/146 (45%), Positives = 89/146 (60%), Gaps = 3/146 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL--DDQYTSSGGTKFPIKWAPP 58
M YLE +IHRDLAARN L+ ++VK+ DFGL R + DD Y K P W P
Sbjct: 240 MGYLEAKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAP 299
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQR-GQVLEKPKGCINE 117
E L FS SD W FGV +WE+FT G+ P+ L S+++ K+ + G+ L +P+ C +
Sbjct: 300 ESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQD 359
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQL 143
IYNVM CW H PE+RP+F L++ L
Sbjct: 360 IYNVMVQCWAHKPEDRPTFVALRDFL 385
>UniRef50_Q07912 Cluster: Activated CDC42 kinase 1; n=24;
Euteleostomi|Rep: Activated CDC42 kinase 1 - Homo
sapiens (Human)
Length = 1036
Score = 141 bits (341), Expect = 7e-33
Identities = 66/146 (45%), Positives = 89/146 (60%), Gaps = 3/146 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL--DDQYTSSGGTKFPIKWAPP 58
M YLE +IHRDLAARN L+ ++VK+ DFGL R + DD Y K P W P
Sbjct: 240 MGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAP 299
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQR-GQVLEKPKGCINE 117
E L FS SD W FGV +WE+FT G+ P+ L S+++ K+ + G+ L +P+ C +
Sbjct: 300 ESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQD 359
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQL 143
IYNVM CW H PE+RP+F L++ L
Sbjct: 360 IYNVMVQCWAHKPEDRPTFVALRDFL 385
>UniRef50_UPI0000E49FB6 Cluster: PREDICTED: similar to RE05926p,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to RE05926p, partial -
Strongylocentrotus purpuratus
Length = 859
Score = 140 bits (340), Expect = 9e-33
Identities = 67/154 (43%), Positives = 98/154 (63%), Gaps = 5/154 (3%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ-YTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN L+G+ V KV+DFGLAR + D Q Y + P++W PE
Sbjct: 444 MEYLASRQCIHRDLAARNILLGEGYVCKVSDFGLARDLEDGQTYEMKSQGRVPVRWMSPE 503
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++S+SDVW+F +L+WE+ T G PY +++ +VV ++ G L KP+ C +IY
Sbjct: 504 SLLHNTYTSQSDVWSFAILIWEIVTLGSHPYPGMSSKQVVKEISAGYRLPKPEHCSQDIY 563
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
N+M+ CW + EERP+F +K +L +++LAD
Sbjct: 564 NLMKECWAYEAEERPTFSQVKVRL----ENMLAD 593
>UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to
protein-tyrosine kinase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
kinase - Strongylocentrotus purpuratus
Length = 837
Score = 140 bits (340), Expect = 9e-33
Identities = 60/143 (41%), Positives = 90/143 (62%), Gaps = 2/143 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV--LDDQYTSSGGTKFPIKWAPP 58
M YLE ++HRDLAARN L+ ++ K++DFGL+R +D Y S+ G ++P+KW P
Sbjct: 672 MMYLEGKKFVHRDLAARNILLENKGQAKISDFGLSRATGANNDYYRSTTGGRWPVKWYAP 731
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E + + FS SDVW FGV +WE+ + G PYG T +EV+ +++ G L +P+GC +
Sbjct: 732 ESIYYGTFSHSSDVWGFGVTLWEMNSRGAQPYGEKTGAEVIKQIENGHRLNRPEGCPQNV 791
Query: 119 YNVMRACWGHTPEERPSFRVLKE 141
Y +M CW + P RP+F L +
Sbjct: 792 YQIMNKCWSYKPCNRPTFSQLND 814
>UniRef50_Q9Y1Y9 Cluster: Protein tyrosine kinase; n=3; Metazoa|Rep:
Protein tyrosine kinase - Ephydatia fluviatilis
Length = 2069
Score = 140 bits (340), Expect = 9e-33
Identities = 69/145 (47%), Positives = 91/145 (62%), Gaps = 4/145 (2%)
Query: 3 YLERHNYIHRDLAARNCLV---GDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPP 58
YL++ ++IHRDLAARNCLV G + VVK+ DFGLA+ + D Y G K P++W P
Sbjct: 1825 YLQQTHFIHRDLAARNCLVSSKGADRVVKIGDFGLAKDLYSSDYYQVEGQRKLPVRWMAP 1884
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E L +F+ +SDVW+FGVLMWE+ T G PY L N EV+ V L+KP+ C +I
Sbjct: 1885 EALLQGKFNMESDVWSFGVLMWEIMTFGNQPYPALNNQEVLQFVTAEGRLQKPENCPGKI 1944
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y +M+ CW ER F V+KE L
Sbjct: 1945 YQLMQNCWKKVASERLHFDVIKEIL 1969
>UniRef50_Q4H2M8 Cluster: Tyrosine-protein kinase receptor; n=1;
Ciona intestinalis|Rep: Tyrosine-protein kinase receptor
- Ciona intestinalis (Transparent sea squirt)
Length = 817
Score = 140 bits (340), Expect = 9e-33
Identities = 68/151 (45%), Positives = 96/151 (63%), Gaps = 3/151 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDD-QYTSSGG-TKFPIKWAPP 58
M +L IHRDLAARN L+ D VVK+ DFGLAR + D Y SGG + PIKW P
Sbjct: 534 MEFLASKKCIHRDLAARNVLLSDYQVVKICDFGLARDIYKDPDYVRSGGDARLPIKWMAP 593
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPY-GRLTNSEVVDKVQRGQVLEKPKGCINE 117
E + +S+KSDVW+FGVL+WE+FT G PY G + + +K++RG + KP+ +
Sbjct: 594 ESIFDKVYSNKSDVWSFGVLLWEIFTLGGSPYPGLQMDEDFCNKLRRGVRMGKPEHATDS 653
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQ 148
+Y+ M CW + PE+RP+F L E+++ + Q
Sbjct: 654 VYSAMLGCWDNNPEDRPTFTKLCEEISDVLQ 684
>UniRef50_O16131 Cluster: Insulin receptor homolog precursor; n=2;
Caenorhabditis elegans|Rep: Insulin receptor homolog
precursor - Caenorhabditis elegans
Length = 1846
Score = 140 bits (340), Expect = 9e-33
Identities = 66/146 (45%), Positives = 94/146 (64%), Gaps = 2/146 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
MAYLE + HRDLAARNC++ + VK+ DFG+AR + D Y SG P++W PE
Sbjct: 1376 MAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPE 1435
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKV-QRGQVLEKPKGCINEI 118
L +F SKSDVW+FGV+++E+ T G PY L+N EV++ + +V++KP+ C N
Sbjct: 1436 SLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYW 1495
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLA 144
Y VM+ CW ++P +RP+F L LA
Sbjct: 1496 YKVMKMCWRYSPRDRPTFLQLVHLLA 1521
>UniRef50_A7RVU0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 337
Score = 140 bits (340), Expect = 9e-33
Identities = 65/151 (43%), Positives = 93/151 (61%), Gaps = 1/151 (0%)
Query: 3 YLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPEVL 61
+L +HRDLAARN LVG + V+KV+DFGLAR + DD Y + P+KW E L
Sbjct: 175 FLASRKCVHRDLAARNVLVGPDYVMKVSDFGLARDIYQDDLYVKNTSGLLPVKWMALESL 234
Query: 62 NFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYNV 121
++ KSDVW+FG+L+WE+ T G PY L +++D + GQ + +P+ C EIY +
Sbjct: 235 FDRVYTEKSDVWSFGILLWEIMTLGGTPYPGLPTEQLLDYLSEGQRMAQPQNCPLEIYTI 294
Query: 122 MRACWGHTPEERPSFRVLKEQLAVISQSVLA 152
MR CW PE+RP F VL ++L + + +A
Sbjct: 295 MRDCWMQLPEQRPHFNVLADRLGKVLERNVA 325
>UniRef50_Q02763 Cluster: Angiopoietin-1 receptor precursor; n=41;
Euteleostomi|Rep: Angiopoietin-1 receptor precursor -
Homo sapiens (Human)
Length = 1124
Score = 140 bits (340), Expect = 9e-33
Identities = 62/136 (45%), Positives = 91/136 (66%), Gaps = 2/136 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YL + +IHRDLAARN LVG+ V K+ADFGL+R + Y + P++W E
Sbjct: 952 MDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRG--QEVYVKKTMGRLPVRWMAIES 1009
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
LN++ +++ SDVW++GVL+WE+ + G PY +T +E+ +K+ +G LEKP C +E+Y+
Sbjct: 1010 LNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYD 1069
Query: 121 VMRACWGHTPEERPSF 136
+MR CW P ERPSF
Sbjct: 1070 LMRQCWREKPYERPSF 1085
>UniRef50_UPI0000D57494 Cluster: PREDICTED: similar to insulin
receptor; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to insulin receptor - Tribolium castaneum
Length = 1351
Score = 140 bits (339), Expect = 1e-32
Identities = 62/138 (44%), Positives = 89/138 (64%), Gaps = 3/138 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK--FPIKWAPP 58
MAYL ++HRDLAARNC+V ++ VK+ DFG+ R + + Y G TK P++W P
Sbjct: 1106 MAYLSAKKFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETDYYRKG-TKGLLPVRWMAP 1164
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E L F+S SDVW++GV++WE+ T PY L+N +V+ V G V+E+P+ C +++
Sbjct: 1165 ESLKDGVFTSNSDVWSYGVVLWEMATLASQPYQGLSNDQVLRYVIDGGVMERPENCPDKL 1224
Query: 119 YNVMRACWGHTPEERPSF 136
Y +MR CW H P RPSF
Sbjct: 1225 YTLMRYCWQHKPSARPSF 1242
>UniRef50_Q9Y1Y5 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 557
Score = 140 bits (339), Expect = 1e-32
Identities = 65/147 (44%), Positives = 89/147 (60%), Gaps = 1/147 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV-LDDQYTSSGGTKFPIKWAPPE 59
M+YL ++HRDLAARNCL+ VKV DFGL R + L + Y + TK P+KW PPE
Sbjct: 411 MSYLADRRFVHRDLAARNCLLDSALAVKVGDFGLTRDIYLTNYYRAPTETKLPVKWMPPE 470
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+L K+DVW+FGV WEVF+ G PY + N ++ + G L+KP C +EIY
Sbjct: 471 MLQDGVSDEKTDVWSFGVTCWEVFSFGSTPYPGVDNHLMLQHLMSGLRLQKPLLCPDEIY 530
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVI 146
+M CW PE+RP+F L ++ + I
Sbjct: 531 TLMARCWSSNPEDRPTFNELFKEFSAI 557
>UniRef50_Q9U5A8 Cluster: Insulin receptor-like protein precursor;
n=1; Bombyx mori|Rep: Insulin receptor-like protein
precursor - Bombyx mori (Silk moth)
Length = 1472
Score = 140 bits (339), Expect = 1e-32
Identities = 65/145 (44%), Positives = 89/145 (61%), Gaps = 3/145 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK--FPIKWAPP 58
MAYL ++HRDLAARNC+V + VKV DFG+ R + + Y G TK P++W P
Sbjct: 1209 MAYLSAKKFVHRDLAARNCMVAGDLTVKVGDFGMTRDIYETDYYRKG-TKGLMPVRWMSP 1267
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E L FSS SD W++GV++WE+ T PY L+N +V+ V G V+E+P+ C + +
Sbjct: 1268 ESLKDGVFSSSSDAWSYGVVLWEMATLAMQPYQGLSNEQVLRYVVEGGVMERPEQCPDRL 1327
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y +MRACW H P RP+F L L
Sbjct: 1328 YELMRACWTHRPSARPTFLQLVADL 1352
>UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55;
Euteleostomi|Rep: Tyrosine-protein kinase ZAP-70 - Homo
sapiens (Human)
Length = 619
Score = 140 bits (339), Expect = 1e-32
Identities = 61/145 (42%), Positives = 98/145 (67%), Gaps = 2/145 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV-LDDQY-TSSGGTKFPIKWAPP 58
M YLE N++HRDLAARN L+ + + K++DFGL++ + DD Y T+ K+P+KW P
Sbjct: 449 MKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAP 508
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E +NF +FSS+SDVW++GV MWE + G+ PY ++ EV+ +++G+ +E P C E+
Sbjct: 509 ECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPEL 568
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y +M CW + E+RP F +++++
Sbjct: 569 YALMSDCWIYKWEDRPDFLTVEQRM 593
>UniRef50_Q24488 Cluster: Tyrosine-protein kinase transmembrane
receptor Ror precursor; n=1; Drosophila
melanogaster|Rep: Tyrosine-protein kinase transmembrane
receptor Ror precursor - Drosophila melanogaster (Fruit
fly)
Length = 685
Score = 140 bits (339), Expect = 1e-32
Identities = 58/144 (40%), Positives = 94/144 (65%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL H+Y+HRDLAARNCLV + VVK++DFGL+R + D Y + P++W P E
Sbjct: 527 MQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSE 586
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + +F+++SDVW+FGV++WE+++ G PY +N EV++ ++ Q+L P+ C +Y
Sbjct: 587 SILYGKFTTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVY 646
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
++M CW +RP+F + +L
Sbjct: 647 SLMIECWHEQSVKRPTFTDISNRL 670
>UniRef50_Q03142 Cluster: Fibroblast growth factor receptor 4
precursor; n=9; Eutheria|Rep: Fibroblast growth factor
receptor 4 precursor - Mus musculus (Mouse)
Length = 799
Score = 140 bits (339), Expect = 1e-32
Identities = 64/144 (44%), Positives = 91/144 (63%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YLE IHRDLAARN LV +++V+K+ADFGLAR V D Y + + P+KW PE
Sbjct: 597 MQYLESRKCIHRDLAARNVLVTEDDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPE 656
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++ +SDVW+F +L+WE+FT G PY + E+ ++ G +E+P C +E+Y
Sbjct: 657 ALFDRVYTHQSDVWSFEILLWEIFTLGGSPYPGIPVEELFSLLREGHRMERPPNCPSELY 716
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+MR CW P +RP+F+ L E L
Sbjct: 717 GLMRECWHAAPSQRPTFKQLVEAL 740
>UniRef50_P22182 Cluster: Fibroblast growth factor receptor 1
precursor; n=33; Euteleostomi|Rep: Fibroblast growth
factor receptor 1 precursor - Xenopus laevis (African
clawed frog)
Length = 812
Score = 140 bits (339), Expect = 1e-32
Identities = 64/144 (44%), Positives = 90/144 (62%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN LV ++N++K+ADFGLAR + D Y + + P+KW PE
Sbjct: 605 MDYLASKKCIHRDLAARNVLVTEDNIMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPE 664
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++ +SDVW+FGVL+WE+FT G PY + E+ ++ G ++KP C NE+Y
Sbjct: 665 ALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPMEELFKLLKEGHRMDKPTNCTNELY 724
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+M+ CW P +RP+F L E L
Sbjct: 725 MMMKDCWHAMPSQRPTFNQLVEDL 748
>UniRef50_UPI0000E471D0 Cluster: PREDICTED: similar to p80 protein,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to p80 protein, partial -
Strongylocentrotus purpuratus
Length = 526
Score = 140 bits (338), Expect = 2e-32
Identities = 61/145 (42%), Positives = 88/145 (60%), Gaps = 4/145 (2%)
Query: 3 YLERHNYIHRDLAARNCLVGDEN---VVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPP 58
YLE +IHRD+AARN L+ + K+ADFG+AR + D Y G P+KW PP
Sbjct: 69 YLESRRFIHRDIAARNILLTTKESGRAAKIADFGMARDIYRADYYRKGGQALLPVKWMPP 128
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E F+SK+DVWA+GVL+WE+ + G +PY ++N EV+ V G+ + P+ C +
Sbjct: 129 EAFQDGIFTSKTDVWAYGVLLWEIISLGFMPYPGMSNQEVIQFVSAGERMNPPRSCPQPV 188
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
+N+M CW H PE+RP F + E +
Sbjct: 189 FNLMSQCWRHIPEDRPPFTTILESI 213
>UniRef50_Q4SR43 Cluster: Chromosome 11 SCAF14528, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF14528, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1373
Score = 140 bits (338), Expect = 2e-32
Identities = 66/149 (44%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGG---TKFPIKWAP 57
M YL + ++HRDLAARNC++ + VKVADFG+AR VLD +Y S K P+KW
Sbjct: 1205 MEYLAQKKFVHRDLAARNCMLDESYTVKVADFGMARDVLDKEYYSVQNHRKAKLPVKWMA 1264
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
E L +F+ KSDVW+FGVLMWE+ T G PY + ++ + RG+ L +P+ C +
Sbjct: 1265 IESLQTQKFTPKSDVWSFGVLMWEMLTRGASPYPDVDPYDITHYLLRGRRLPQPQFCPDP 1324
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVI 146
+Y +M CW PE RPSF L +++I
Sbjct: 1325 LYRIMLQCWDPEPELRPSFATLVSAVSII 1353
>UniRef50_Q4RWP2 Cluster: Tyrosine-protein kinase receptor; n=1;
Tetraodon nigroviridis|Rep: Tyrosine-protein kinase
receptor - Tetraodon nigroviridis (Green puffer)
Length = 1419
Score = 140 bits (338), Expect = 2e-32
Identities = 60/144 (41%), Positives = 90/144 (62%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKF-PIKWAPPE 59
MAYL ++HRDLAARNC+VG + VK+ DFG+ R + + Y GG P++W PE
Sbjct: 1183 MAYLNAKKFVHRDLAARNCMVGHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPE 1242
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L F++ SD W+FGV++WE+ T + PY L+N +V+ V G L++P C + +Y
Sbjct: 1243 SLKDGVFTAHSDCWSFGVVLWEISTLSEQPYQGLSNEQVLKFVMDGGYLDRPDNCPDRLY 1302
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
N+M+ CW + P+ RP+F + E L
Sbjct: 1303 NLMQMCWQYNPKMRPTFLEIIEML 1326
>UniRef50_Q9Y1Y6 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 948
Score = 140 bits (338), Expect = 2e-32
Identities = 60/136 (44%), Positives = 91/136 (66%), Gaps = 1/136 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTS-SGGTKFPIKWAPPE 59
+AYL ++YIHRDLA RNCLV + +K++DFGL++ + Y S PI+W PPE
Sbjct: 749 LAYLADNHYIHRDLATRNCLVSGDLRIKISDFGLSQDIYSTDYCRLSQSELLPIRWMPPE 808
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ F RF+++SDVW+ GV++WE+F+ G PY ++N +V+ V+ G V+ P GC +EIY
Sbjct: 809 AILFARFTTQSDVWSLGVVLWELFSYGIQPYYSMSNEQVIAHVRDGNVMNCPDGCPSEIY 868
Query: 120 NVMRACWGHTPEERPS 135
++M CW P +RP+
Sbjct: 869 DLMVDCWNMDPGQRPT 884
>UniRef50_P35590 Cluster: Tyrosine-protein kinase receptor Tie-1
precursor; n=37; Deuterostomia|Rep: Tyrosine-protein
kinase receptor Tie-1 precursor - Homo sapiens (Human)
Length = 1138
Score = 140 bits (338), Expect = 2e-32
Identities = 62/143 (43%), Positives = 93/143 (65%), Gaps = 2/143 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YL +IHRDLAARN LVG+ K+ADFGL+R ++ Y + P++W E
Sbjct: 967 MQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSRG--EEVYVKKTMGRLPVRWMAIES 1024
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
LN++ +++KSDVW+FGVL+WE+ + G PY +T +E+ +K+ +G +E+P+ C +E+Y
Sbjct: 1025 LNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYE 1084
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+MR CW P ERP F + QL
Sbjct: 1085 LMRQCWRDRPYERPPFAQIALQL 1107
>UniRef50_P08069 Cluster: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (Insulin-like growth factor I
receptor) (IGF-I receptor) (CD221 antigen) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain]; n=47;
Euteleostomi|Rep: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (Insulin-like growth factor I
receptor) (IGF-I receptor) (CD221 antigen) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain] - Homo
sapiens (Human)
Length = 1367
Score = 140 bits (338), Expect = 2e-32
Identities = 59/137 (43%), Positives = 89/137 (64%), Gaps = 1/137 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKF-PIKWAPPE 59
MAYL + ++HRDLAARNC+V ++ VK+ DFG+ R + + Y GG P++W PE
Sbjct: 1123 MAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPE 1182
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L F++ SDVW+FGV++WE+ T + PY L+N +V+ V G +L+KP C + ++
Sbjct: 1183 SLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLF 1242
Query: 120 NVMRACWGHTPEERPSF 136
+MR CW + P+ RPSF
Sbjct: 1243 ELMRMCWQYNPKMRPSF 1259
>UniRef50_Q8JG38 Cluster: Fibroblast growth factor receptor 2
precursor; n=11; Eumetazoa|Rep: Fibroblast growth factor
receptor 2 precursor - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 817
Score = 140 bits (338), Expect = 2e-32
Identities = 66/144 (45%), Positives = 89/144 (61%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN LV + NV+K+ADFGLAR V + D Y + + P+KW PE
Sbjct: 610 MEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPE 669
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++ +SDVW+FGVLMWE+FT G PY + E+ ++ G ++KP C NE+Y
Sbjct: 670 ALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELY 729
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+M+ CW RP+F+ L E L
Sbjct: 730 MMMKDCWHAISSHRPTFKQLVEDL 753
>UniRef50_P21709 Cluster: Ephrin type-A receptor 1 precursor; n=19;
Mammalia|Rep: Ephrin type-A receptor 1 precursor - Homo
sapiens (Human)
Length = 976
Score = 140 bits (338), Expect = 2e-32
Identities = 64/145 (44%), Positives = 87/145 (60%), Gaps = 3/145 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV--LDDQYTSSGGTKFPIKWAPP 58
M YL HNY+HRDLAARN LV KV+DFGL R + D Y + GG K PI+W P
Sbjct: 737 MNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGG-KIPIRWTAP 795
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E + F++ SDVW+FG++MWEV + G PYG ++N EV+ ++ G L P C +
Sbjct: 796 EAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPL 855
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y +M+ CW + RP F+ L+ L
Sbjct: 856 YELMKNCWAYDRARRPHFQKLQAHL 880
>UniRef50_UPI00004D7E5F Cluster: Proto-oncogene tyrosine-protein
kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor
tyrosine kinase MerTK).; n=1; Xenopus tropicalis|Rep:
Proto-oncogene tyrosine-protein kinase MER precursor (EC
2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK). -
Xenopus tropicalis
Length = 763
Score = 139 bits (336), Expect = 3e-32
Identities = 66/151 (43%), Positives = 90/151 (59%), Gaps = 1/151 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGG-TKFPIKWAPPE 59
M YL N++HRDLAARNC++ D+ V VADFGL++ + Y G K P+KW E
Sbjct: 595 MEYLSSRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAVE 654
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++ KSDVWAFGV MWE+ T G PY + N E+ D + G L++P C++++Y
Sbjct: 655 SLADRIYTVKSDVWAFGVTMWEISTRGMTPYPGVQNHEIYDYLLVGHRLKQPPECLDDLY 714
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQSV 150
VM CW P RPSF L+E L I + +
Sbjct: 715 TVMYQCWLSDPTCRPSFTALRENLEKIVEGL 745
>UniRef50_A7SAX2 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 315
Score = 139 bits (336), Expect = 3e-32
Identities = 61/148 (41%), Positives = 91/148 (61%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MA+L + +HRDLAARN LVG+ N K++D GLAR V D YT + + P+KW PPE
Sbjct: 163 MAFLAANKCVHRDLAARNVLVGEHNTCKISDLGLARDVSQDIYTRTSSARLPVKWMPPES 222
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + + SS SDVW++G+++WE+FT G PY + + + ++ G + KP + +Y
Sbjct: 223 LLYGQSSSASDVWSYGIVLWEIFTIGDSPYPGVKSKGIPRMLREGYRMPKPPHVGDALYF 282
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQ 148
VM CW P+ERP+F L + + + Q
Sbjct: 283 VMLRCWQEDPDERPTFDELCDNMQALQQ 310
>UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18;
Euteleostomi|Rep: Transmembrane receptor PTK7-2 - Homo
sapiens (Human)
Length = 1030
Score = 138 bits (335), Expect = 4e-32
Identities = 62/144 (43%), Positives = 95/144 (65%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M +L + ++H+DLAARNCLV + VKV+ GL++ V + +Y P++W PE
Sbjct: 878 MEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEA 937
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQV-LEKPKGCINEIY 119
+ FS+KSDVWAFGVLMWEVFT G++P+G + EV+ +Q G+ L +P+GC +++Y
Sbjct: 938 ILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLY 997
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+M+ CW +P++RPSF + L
Sbjct: 998 RLMQRCWALSPKDRPSFSEIASAL 1021
>UniRef50_P23049 Cluster: Tyrosine-protein kinase transforming
protein SEA; n=6; root|Rep: Tyrosine-protein kinase
transforming protein SEA - Avian erythroblastosis virus
(strain S13)
Length = 370
Score = 138 bits (335), Expect = 4e-32
Identities = 68/153 (44%), Positives = 95/153 (62%), Gaps = 3/153 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTS---SGGTKFPIKWAP 57
M YL + ++HRDLAARNC++ + VKVADFGLAR V +Y S K P++W
Sbjct: 174 MEYLAQKKFVHRDLAARNCMLDETLTVKVADFGLARDVFGKEYYSIRQHRHAKLPVRWMA 233
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
E L +F++KSDVW+FGVLMWE+ T G PY + ++ + RG+ L +P+ C +
Sbjct: 234 LESLQTQKFTTKSDVWSFGVLMWELLTRGASPYPEVDPYDMARYLLRGRRLPQPQPCPDT 293
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQSV 150
+Y VM +CW TPEERPSF L +L + S+
Sbjct: 294 LYGVMLSCWAPTPEERPSFSGLVCELERVLASL 326
>UniRef50_P00529 Cluster: Tyrosine-protein kinase transforming
protein ros; n=3; root|Rep: Tyrosine-protein kinase
transforming protein ros - Avian sarcoma virus (strain
UR2)
Length = 402
Score = 138 bits (335), Expect = 4e-32
Identities = 70/156 (44%), Positives = 94/156 (60%), Gaps = 7/156 (4%)
Query: 3 YLERHNYIHRDLAARNCLVGDEN------VVKVADFGLARYVL-DDQYTSSGGTKFPIKW 55
YLE+ +IHRDLAARNCLV ++ VVK+ DFGLAR + +D Y G P++W
Sbjct: 222 YLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYKNDYYRKRGEGLLPVRW 281
Query: 56 APPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCI 115
PE L F++ SDVWAFGVL+WE T G+ PY L+N EV+ V+ G LE P C
Sbjct: 282 MAPESLIDGVFTNHSDVWAFGVLVWETLTLGQQPYPGLSNIEVLHHVRSGGRLESPNNCP 341
Query: 116 NEIYNVMRACWGHTPEERPSFRVLKEQLAVISQSVL 151
++I ++M CW P RP+F ++ +L I S L
Sbjct: 342 DDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIRHSPL 377
>UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precursor;
n=29; Tetrapoda|Rep: Tyrosine-protein kinase-like 7
precursor - Homo sapiens (Human)
Length = 1070
Score = 138 bits (335), Expect = 4e-32
Identities = 62/144 (43%), Positives = 95/144 (65%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M +L + ++H+DLAARNCLV + VKV+ GL++ V + +Y P++W PE
Sbjct: 918 MEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEA 977
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQV-LEKPKGCINEIY 119
+ FS+KSDVWAFGVLMWEVFT G++P+G + EV+ +Q G+ L +P+GC +++Y
Sbjct: 978 ILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLY 1037
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+M+ CW +P++RPSF + L
Sbjct: 1038 RLMQRCWALSPKDRPSFSEIASAL 1061
>UniRef50_O02466 Cluster: Insulin-like peptide receptor precursor (EC
2.7.10.1) (ILP receptor) [Contains: Insulin-like peptide
receptor alpha chain; Insulin-like peptide receptor beta
chain]; n=4; Eukaryota|Rep: Insulin-like peptide receptor
precursor (EC 2.7.10.1) (ILP receptor) [Contains:
Insulin-like peptide receptor alpha chain; Insulin-like
peptide receptor beta chain] - Branchiostoma lanceolatum
(Common lancelet) (Amphioxus)
Length = 1363
Score = 138 bits (335), Expect = 4e-32
Identities = 60/145 (41%), Positives = 91/145 (62%), Gaps = 1/145 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKF-PIKWAPPE 59
M+YL ++HRDLA RNC+V + VK+ DFG+ R + + Y GG P++W PE
Sbjct: 1136 MSYLAAKKFVHRDLACRNCMVAQDRTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPE 1195
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L F+S+SDVW++GV++WE+ T PY +N EV+ V G +LEKP+GC N++Y
Sbjct: 1196 SLKVGVFTSQSDVWSYGVVLWEMATLASQPYQGKSNEEVLKFVIDGGMLEKPEGCPNKLY 1255
Query: 120 NVMRACWGHTPEERPSFRVLKEQLA 144
++M+ CW + RP+F + E L+
Sbjct: 1256 DLMKLCWQYRQSMRPTFLEIVEILS 1280
>UniRef50_Q4S1S8 Cluster: Chromosome undetermined SCAF14764, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14764,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 635
Score = 138 bits (334), Expect = 5e-32
Identities = 67/144 (46%), Positives = 89/144 (61%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
MAYL IHRDLAARN LV ++NV+K+ADFGLAR V D Y + + P+KW PE
Sbjct: 481 MAYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDVHHIDYYKKTTNGRLPVKWMAPE 540
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++ +SDVW+FGVL+WE+FT G PY + E+ ++ G +EKP E+Y
Sbjct: 541 ALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMEKPPTSTQELY 600
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+MR CW P RP+F+ L E L
Sbjct: 601 LMMRGCWHAVPARRPTFQQLVEDL 624
>UniRef50_Q7Q0F6 Cluster: Tyrosine-protein kinase receptor; n=2;
Cellia|Rep: Tyrosine-protein kinase receptor - Anopheles
gambiae str. PEST
Length = 1318
Score = 138 bits (334), Expect = 5e-32
Identities = 61/137 (44%), Positives = 87/137 (63%), Gaps = 1/137 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKF-PIKWAPPE 59
MAYL ++HRDLAARNC+V ++ VK+ DFG+ R + + Y G F P++W PE
Sbjct: 1118 MAYLAAKKFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETDYYRKGTKGFLPVRWMAPE 1177
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L FSS SDV+++GV++WE+ T PY LTN +V+ V G V+E+P+ C +++Y
Sbjct: 1178 SLKDGMFSSSSDVFSYGVVLWEMATLASQPYQGLTNDQVLRYVIDGGVMERPENCPDKLY 1237
Query: 120 NVMRACWGHTPEERPSF 136
+MR CW H RPSF
Sbjct: 1238 ELMRICWQHRASARPSF 1254
>UniRef50_Q5DM52 Cluster: Receptor tyrosine kinase Torso-like
protein; n=1; Tribolium castaneum|Rep: Receptor tyrosine
kinase Torso-like protein - Tribolium castaneum (Red
flour beetle)
Length = 803
Score = 138 bits (334), Expect = 5e-32
Identities = 64/151 (42%), Positives = 95/151 (62%), Gaps = 1/151 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ-YTSSGGTKFPIKWAPPE 59
M +L + +HRDLAARN LV + + VKV+DFGL+R V D Y +GG K P++W E
Sbjct: 605 MEHLAKTRVVHRDLAARNVLVCENHTVKVSDFGLSRDVYQDNVYCKNGGGKLPVRWMALE 664
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L R+++ SDVW+FGVL+WE+ T G PY + +SE++D ++ G L +P C ++Y
Sbjct: 665 SLTHQRYTTYSDVWSFGVLLWEIVTLGGTPYVGVHSSELLDFLKSGNRLARPANCSPDLY 724
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQSV 150
VM CW P+ RP+F L + L + ++V
Sbjct: 725 AVMLNCWKECPKNRPTFTELSKSLEGLLENV 755
>UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hydra
vulgaris|Rep: Protein-tyrosine kinase HTK98 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 624
Score = 138 bits (334), Expect = 5e-32
Identities = 60/138 (43%), Positives = 89/138 (64%), Gaps = 2/138 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARY--VLDDQYTSSGGTKFPIKWAPP 58
M YLE +++HRDLAARN LV EN VK++DFG++R V ++ Y + K+P+KW P
Sbjct: 468 MNYLESQHFVHRDLAARNVLVVSENFVKISDFGMSRAMGVGNEYYRAERAGKWPLKWYAP 527
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E + + +FSSK DVW++G+ MWE + G PY + +V+K++ G L KP C + +
Sbjct: 528 ECIYYHKFSSKGDVWSYGITMWEAVSYGGKPYQGMRGPVIVEKLESGYRLPKPDNCSDAV 587
Query: 119 YNVMRACWGHTPEERPSF 136
Y +M CW P++RPSF
Sbjct: 588 YTLMLKCWETNPDDRPSF 605
>UniRef50_Q01973 Cluster: Tyrosine-protein kinase transmembrane
receptor ROR1 precursor; n=21; Euteleostomi|Rep:
Tyrosine-protein kinase transmembrane receptor ROR1
precursor - Homo sapiens (Human)
Length = 937
Score = 138 bits (334), Expect = 5e-32
Identities = 58/144 (40%), Positives = 92/144 (63%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL H ++H+DLAARN L+G++ VK++D GL+R + D Y + PI+W PPE
Sbjct: 603 MEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSLLPIRWMPPE 662
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + +FSS SD+W+FGV++WE+F+ G PY +N EV++ V++ Q+L + C +Y
Sbjct: 663 AIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMY 722
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
++M CW P RP F+ + +L
Sbjct: 723 SLMTECWNEIPSRRPRFKDIHVRL 746
>UniRef50_P16234 Cluster: Alpha-type platelet-derived growth factor
receptor precursor; n=55; Vertebrata|Rep: Alpha-type
platelet-derived growth factor receptor precursor - Homo
sapiens (Human)
Length = 1089
Score = 138 bits (334), Expect = 5e-32
Identities = 61/143 (42%), Positives = 89/143 (62%), Gaps = 2/143 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
M +L N +HRDLAARN L+ +VK+ DFGLAR ++ D Y S G T P+KW PE
Sbjct: 806 MEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPE 865
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPY-GRLTNSEVVDKVQRGQVLEKPKGCINEI 118
+ +++ SDVW++G+L+WE+F+ G PY G + +S +K++ G + KP +E+
Sbjct: 866 SIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEV 925
Query: 119 YNVMRACWGHTPEERPSFRVLKE 141
Y +M CW PE+RPSF L E
Sbjct: 926 YEIMVKCWNSEPEKRPSFYHLSE 948
>UniRef50_UPI000065F647 Cluster: Ephrin type-B receptor 2 precursor
(EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3)
(DRT) (Receptor protein-tyrosine kinase HEK5) (ERK)
(Renal carcinoma antigen NY-REN-47).; n=1; Takifugu
rubripes|Rep: Ephrin type-B receptor 2 precursor (EC
2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT)
(Receptor protein-tyrosine kinase HEK5) (ERK) (Renal
carcinoma antigen NY-REN-47). - Takifugu rubripes
Length = 986
Score = 138 bits (333), Expect = 6e-32
Identities = 62/147 (42%), Positives = 91/147 (61%), Gaps = 4/147 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ----YTSSGGTKFPIKWA 56
M YL NY+HRDLAARN LV V KV+DFGL+R++ DD YTS+ G K PI+W
Sbjct: 752 MKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWT 811
Query: 57 PPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCIN 116
PE + + +F+S SDVW++G++MWEV + G+ PY +TN +V++ +++ L P C +
Sbjct: 812 APEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPS 871
Query: 117 EIYNVMRACWGHTPEERPSFRVLKEQL 143
++ +M CW RP F + L
Sbjct: 872 TLHQLMLDCWQKDRNNRPKFSQIVNNL 898
>UniRef50_Q64GK4 Cluster: C-Met receptor tyrosine kinase; n=9;
Clupeocephala|Rep: C-Met receptor tyrosine kinase - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 1382
Score = 138 bits (333), Expect = 6e-32
Identities = 66/152 (43%), Positives = 94/152 (61%), Gaps = 3/152 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTS---SGGTKFPIKWAP 57
M YL ++HRDLAARNC++ + VKVAD GLAR V D +Y S G K P+KW
Sbjct: 1193 MEYLASKKFVHRDLAARNCMLDESYTVKVADVGLARDVYDKEYYSVHNKHGVKLPVKWMA 1252
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
E L +F++KSDVW+FGVL+WE+ T G PY + + ++ + +G+ L +P+ C +
Sbjct: 1253 LESLQTHKFTTKSDVWSFGVLLWELMTRGAPPYSDVNSFDITVFLLQGRRLLQPEFCPDA 1312
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQS 149
+YNVM CW PE RP+F L +++ I S
Sbjct: 1313 LYNVMIECWHPKPERRPTFLELVSRISAIFSS 1344
>UniRef50_Q9Y1Y8 Cluster: Protein tyrosine kinase; n=2; Metazoa|Rep:
Protein tyrosine kinase - Ephydatia fluviatilis
Length = 985
Score = 138 bits (333), Expect = 6e-32
Identities = 68/158 (43%), Positives = 98/158 (62%), Gaps = 6/158 (3%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
M YL N+IHRDLA RNCLVG + VVK+ADFG++R + +D Y G PI+W E
Sbjct: 824 MRYLAERNFIHRDLATRNCLVGAKYVVKIADFGMSRSLYSNDYYKLRGRAMLPIRWMAKE 883
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGK-VPYGRLTNSEVVDKV--QRGQV-LEKPKGCI 115
+ +FS K+DVWAFGV+MWE+FT K PY +++ +V++ + G++ L +P C
Sbjct: 884 CF-YGKFSQKTDVWAFGVVMWEIFTFSKRQPYDEMSDQQVIENAIEKSGRILLARPHNCP 942
Query: 116 NEIYNVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
E+Y VM CW + PE R +F L + L I ++ +D
Sbjct: 943 KEVYEVMLQCWENDPETRATFEELFQSLTSIHAAMHSD 980
>UniRef50_Q93105 Cluster: Insulin-like receptor precursor (EC
2.7.10.1) (MIR) [Contains: Insulin-like receptor alpha
chain; Insulin-like receptor beta chain]; n=2; Aedes
aegypti|Rep: Insulin-like receptor precursor (EC
2.7.10.1) (MIR) [Contains: Insulin-like receptor alpha
chain; Insulin-like receptor beta chain] - Aedes aegypti
(Yellowfever mosquito)
Length = 1390
Score = 138 bits (333), Expect = 6e-32
Identities = 61/141 (43%), Positives = 88/141 (62%), Gaps = 1/141 (0%)
Query: 4 LERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKF-PIKWAPPEVLN 62
L ++HRDLAARNC+V D+ VK+ DFG+ R + + Y G F P++W PE L
Sbjct: 1153 LSAKKFVHRDLAARNCMVADDMTVKIGDFGMTRDIYETDYYRKGTKGFLPVRWMAPESLK 1212
Query: 63 FTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYNVM 122
FSS SDV+++GV++WE+ T PY LTN +V+ V G V+E+P+ C + +YN+M
Sbjct: 1213 DGIFSSSSDVFSYGVVLWEMATLASQPYQGLTNDQVLRYVIDGGVMERPENCPDNLYNLM 1272
Query: 123 RACWGHTPEERPSFRVLKEQL 143
R CW H P RP+F + +L
Sbjct: 1273 RRCWQHRPTARPTFMEIISEL 1293
>UniRef50_O73798 Cluster: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (xIGF- 1R) (xIGFR) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain]; n=25;
Euteleostomi|Rep: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (xIGF- 1R) (xIGFR) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain] -
Xenopus laevis (African clawed frog)
Length = 1358
Score = 138 bits (333), Expect = 6e-32
Identities = 58/137 (42%), Positives = 88/137 (64%), Gaps = 1/137 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKF-PIKWAPPE 59
M+YL + ++HRDLAARNC+V ++ VK+ DFG+ R + + Y GG P++W PE
Sbjct: 1119 MSYLNANKFVHRDLAARNCMVTEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPE 1178
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L F++ SDVW+FGV++WE+ T + PY ++N +V+ V G +LEKP C + ++
Sbjct: 1179 SLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLF 1238
Query: 120 NVMRACWGHTPEERPSF 136
+MR CW P+ RPSF
Sbjct: 1239 ELMRMCWQFNPKMRPSF 1255
>UniRef50_A2CG59 Cluster: Eph receptor B1; n=23; Euteleostomi|Rep:
Eph receptor B1 - Mus musculus (Mouse)
Length = 943
Score = 137 bits (332), Expect = 9e-32
Identities = 61/140 (43%), Positives = 88/140 (62%), Gaps = 4/140 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ----YTSSGGTKFPIKWA 56
M YL NY+HRDLAARN LV V KV+DFGL+RY+ DD YTSS G K P++W
Sbjct: 691 MKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWT 750
Query: 57 PPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCIN 116
PE + + +F+S SDVW++G++MWEV + G+ PY ++N +V++ +++ L P C
Sbjct: 751 APEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPA 810
Query: 117 EIYNVMRACWGHTPEERPSF 136
++ +M CW RP F
Sbjct: 811 ALHQLMLDCWQKDRNSRPRF 830
>UniRef50_Q9V4E5 Cluster: CG1511-PC, isoform C; n=12; Diptera|Rep:
CG1511-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 1096
Score = 137 bits (332), Expect = 9e-32
Identities = 60/138 (43%), Positives = 88/138 (63%), Gaps = 3/138 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV--LDDQYTSSGGTKFPIKWAPP 58
M+YL NY+HRDLAARN LV + + K+ADFGL+R + D YT+ GG K P++W P
Sbjct: 856 MSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIENASDAYTTRGG-KIPVRWTAP 914
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E + F +F+S SDVW++GV++WEV + G+ PY +N +V+ +++G L P C +
Sbjct: 915 EAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAL 974
Query: 119 YNVMRACWGHTPEERPSF 136
Y +M CW RP+F
Sbjct: 975 YQLMLDCWQKQRTHRPTF 992
>UniRef50_Q7PYY7 Cluster: ENSANGP00000019144; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019144 - Anopheles gambiae
str. PEST
Length = 687
Score = 137 bits (332), Expect = 9e-32
Identities = 65/150 (43%), Positives = 90/150 (60%), Gaps = 1/150 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ-YTSSGGTKFPIKWAPPE 59
M +L IHRDLAARN L+ D++ KVADFG AR ++ + Y + PI+W E
Sbjct: 512 MDFLTSRGIIHRDLAARNILITDDHTCKVADFGFARDIVTSKVYERKSEGRLPIRWMATE 571
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L F+ KSD+W+FG+LMWE+ T G PY + ++V+ KV+ G LEKP+ C E+Y
Sbjct: 572 SLYDNIFTVKSDIWSFGILMWEIVTLGSTPYPGIAAADVMRKVRDGYRLEKPEHCRRELY 631
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQS 149
N+M CW P ERP F + E L + Q+
Sbjct: 632 NIMFYCWAADPNERPGFPEVVEMLDRLLQT 661
>UniRef50_Q7PWP1 Cluster: ENSANGP00000013218; n=2; Culicidae|Rep:
ENSANGP00000013218 - Anopheles gambiae str. PEST
Length = 861
Score = 137 bits (332), Expect = 9e-32
Identities = 64/147 (43%), Positives = 89/147 (60%), Gaps = 1/147 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
MAYL +HRDLAARN L+ + V K++DFGL R V DD Y + P+KW PE
Sbjct: 615 MAYLTDIKLVHRDLAARNVLLAEGKVCKISDFGLTRDVYEDDAYLKKSKDRVPVKWMAPE 674
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L +++KSDVWAFGVL WE+ T G PY + + + +++G +E PK C EIY
Sbjct: 675 SLADHIYTTKSDVWAFGVLCWELITLGASPYPGIPPQNLYNLLKQGYRMECPKNCSEEIY 734
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVI 146
++R CW P++RPSF+ L Q ++
Sbjct: 735 GIVRLCWADDPKQRPSFKHLAGQFELL 761
>UniRef50_A7SL46 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 252
Score = 137 bits (332), Expect = 9e-32
Identities = 60/141 (42%), Positives = 89/141 (63%), Gaps = 1/141 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ-YTSSGGTKFPIKWAPPE 59
M YL + ++HRDLAARN LV D VKVADFGL R + ++ Y K PIKW PE
Sbjct: 94 MEYLSKKGFVHRDLAARNVLVADNKQVKVADFGLTRDLYEESAYQGHSNRKLPIKWMSPE 153
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ F+++SDVW++GV++WE+ T G PY ++ +V ++ G +EKP C +E+Y
Sbjct: 154 AIYDQIFTTESDVWSYGVVLWEIATLGGAPYPTISTRDVFVMLRSGYRMEKPDICSDEVY 213
Query: 120 NVMRACWGHTPEERPSFRVLK 140
+M+ CW P++RP+F L+
Sbjct: 214 TIMKHCWEDQPKKRPTFSDLR 234
>UniRef50_P18475 Cluster: Tyrosine-protein kinase receptor torso
precursor; n=2; Sophophora|Rep: Tyrosine-protein kinase
receptor torso precursor - Drosophila melanogaster
(Fruit fly)
Length = 923
Score = 137 bits (332), Expect = 9e-32
Identities = 60/145 (41%), Positives = 98/145 (67%), Gaps = 2/145 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ-YTSSGGT-KFPIKWAPP 58
M +L ++ +HRDLAARN L+ + +K+ADFGL+R V + Y SGG+ K PIKW
Sbjct: 729 MEFLAQNKVVHRDLAARNVLISVDRSIKIADFGLSRDVYHENVYRKSGGSGKLPIKWLAL 788
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E L ++S+SDVW+FGVL++E+ T G +PY ++ S+++ +++G +++P+GC E+
Sbjct: 789 ESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEM 848
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
+++M +CW P RP+F LK +L
Sbjct: 849 FSLMESCWSSVPSHRPTFSALKHRL 873
>UniRef50_P29323 Cluster: Ephrin type-B receptor 2 precursor; n=311;
Eumetazoa|Rep: Ephrin type-B receptor 2 precursor - Homo
sapiens (Human)
Length = 1055
Score = 137 bits (332), Expect = 9e-32
Identities = 61/140 (43%), Positives = 89/140 (63%), Gaps = 4/140 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ----YTSSGGTKFPIKWA 56
M YL NY+HRDLAARN LV V KV+DFGL+R++ DD YTS+ G K PI+W
Sbjct: 734 MKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWT 793
Query: 57 PPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCIN 116
PE + + +F+S SDVW++G++MWEV + G+ PY +TN +V++ +++ L P C +
Sbjct: 794 APEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPS 853
Query: 117 EIYNVMRACWGHTPEERPSF 136
++ +M CW RP F
Sbjct: 854 ALHQLMLDCWQKDRNHRPKF 873
>UniRef50_UPI0000D55449 Cluster: PREDICTED: similar to CG7223-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7223-PA, isoform A - Tribolium castaneum
Length = 861
Score = 137 bits (331), Expect = 1e-31
Identities = 65/145 (44%), Positives = 91/145 (62%), Gaps = 2/145 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV-LDDQYTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN LV D+ +K+ADFGLAR + +D Y + + P+KW PE
Sbjct: 665 MEYLASRRCIHRDLAARNVLVSDDYFLKIADFGLARDIHCNDYYRKTTDGRLPVKWMAPE 724
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQR-GQVLEKPKGCINEI 118
L ++++SDVW++G+L+WE+ T G PY + + E + ++ R G +EKP C EI
Sbjct: 725 ALFHRVYTTQSDVWSYGILLWEIMTLGGTPYPSVPSVEKLFQLLRNGHRMEKPPCCSLEI 784
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y +MR CW + P ERP+F L E L
Sbjct: 785 YMLMRECWSYKPNERPTFSQLVEDL 809
>UniRef50_Q6PFV6 Cluster: Ephrin receptor; n=11; Tetrapoda|Rep:
Ephrin receptor - Mus musculus (Mouse)
Length = 819
Score = 137 bits (331), Expect = 1e-31
Identities = 63/139 (45%), Positives = 85/139 (61%), Gaps = 4/139 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL Y+HRDLAARN L+ V KV+DFGL+R + DD YT+ GG K PI+W
Sbjct: 604 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGG-KIPIRWTA 662
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + F +F+S SDVW++G++MWEV + G+ PY +TN +V+ V+ G L P C
Sbjct: 663 PEAIAFRKFTSSSDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAA 722
Query: 118 IYNVMRACWGHTPEERPSF 136
+Y +M CW RP F
Sbjct: 723 LYQLMLDCWQKDRNSRPKF 741
>UniRef50_UPI000065E56D Cluster: EPHB1_HUMAN Isoform 3 of P54762 -
Homo sapiens (Human); n=1; Takifugu rubripes|Rep:
EPHB1_HUMAN Isoform 3 of P54762 - Homo sapiens (Human) -
Takifugu rubripes
Length = 983
Score = 136 bits (330), Expect = 1e-31
Identities = 60/140 (42%), Positives = 89/140 (63%), Gaps = 4/140 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDD----QYTSSGGTKFPIKWA 56
M YL NY+HRDLAARN LV V KV+DFGL+RY+ +D YTSS G K P++W
Sbjct: 731 MKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQEDTSDPSYTSSLGGKIPVRWT 790
Query: 57 PPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCIN 116
PE + + +F+S SDVW++G++MWEV + G+ PY ++N +V++ +++ L P C +
Sbjct: 791 APEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPS 850
Query: 117 EIYNVMRACWGHTPEERPSF 136
++ +M CW RP F
Sbjct: 851 TLHQLMLDCWQKDRNVRPRF 870
>UniRef50_P54756 Cluster: Ephrin type-A receptor 5 precursor; n=103;
Euteleostomi|Rep: Ephrin type-A receptor 5 precursor -
Homo sapiens (Human)
Length = 1037
Score = 136 bits (330), Expect = 1e-31
Identities = 63/139 (45%), Positives = 85/139 (61%), Gaps = 4/139 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL Y+HRDLAARN L+ V KV+DFGL+R + DD YT+ GG K PI+W
Sbjct: 788 MKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGG-KIPIRWTA 846
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + F +F+S SDVW++G++MWEV + G+ PY +TN +V+ V+ G L P C
Sbjct: 847 PEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAA 906
Query: 118 IYNVMRACWGHTPEERPSF 136
+Y +M CW RP F
Sbjct: 907 LYQLMLDCWQKERNSRPKF 925
>UniRef50_UPI00015B54DC Cluster: PREDICTED: similar to vascular
endothelial growth factor receptor 2; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to vascular
endothelial growth factor receptor 2 - Nasonia
vitripennis
Length = 1005
Score = 136 bits (329), Expect = 2e-31
Identities = 65/148 (43%), Positives = 87/148 (58%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M YL + N +H DLAARN L+ NVVK+ DFGLA+ + DD Y PIKW E
Sbjct: 818 MEYLSQKNVLHGDLAARNILLTHNNVVKICDFGLAKVMEDDSYMKRSRGLLPIKWMAIES 877
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+ FS SDVW+FG+++WE FT +VPY + + K+ +G LEKPK EIY+
Sbjct: 878 IRDRVFSVHSDVWSFGIVLWEFFTLAQVPYCDILPEVQLQKLLKGHRLEKPKYANGEIYS 937
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVISQ 148
+M CW P RP+F +L EQ+ + Q
Sbjct: 938 IMVPCWNEEPTLRPTFTMLVEQIGDLLQ 965
>UniRef50_UPI0000D57178 Cluster: PREDICTED: similar to CG14396-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG14396-PA, isoform A - Tribolium castaneum
Length = 1065
Score = 136 bits (329), Expect = 2e-31
Identities = 61/154 (39%), Positives = 96/154 (62%), Gaps = 5/154 (3%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
MAYL +HRDLAARN L+ + + K++DFGL R + DD Y + P+KW PE
Sbjct: 885 MAYLSEIKLVHRDLAARNVLLAADQICKISDFGLTRDIYEDDAYFKRSKGRVPVKWMAPE 944
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L+ +++KSDVW+FG+L+WE+ T G PY + + +++G +E+P C +Y
Sbjct: 945 SLSDHIYTNKSDVWSFGILVWELVTLGATPYPGIAVQNLFHLLRQGYRMERPDNCSPTLY 1004
Query: 120 NVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
N+MR+CW PE+RP+F ++LA + + +L+D
Sbjct: 1005 NIMRSCWHIDPEQRPTF----QELAALWEKMLSD 1034
>UniRef50_Q8T0W6 Cluster: Putative insulin receptor precursor; n=1;
Echinococcus multilocularis|Rep: Putative insulin
receptor precursor - Echinococcus multilocularis
Length = 1749
Score = 136 bits (329), Expect = 2e-31
Identities = 67/148 (45%), Positives = 90/148 (60%), Gaps = 4/148 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
MAYLER Y+HRDLAARNCLV VVKV DFGL R + + + Y G K P++W PE
Sbjct: 1466 MAYLERKKYVHRDLAARNCLVDGRGVVKVGDFGLCRDIYERNYYHKVGAGKLPVRWMAPE 1525
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEK---PKGCIN 116
L F+S+SDVW+FGV++WE+ T +PY ++++EV+ V G L P C
Sbjct: 1526 SLQSAYFTSRSDVWSFGVVLWEIATMACLPYQGMSHNEVISYVLDGNTLVSGGAPINCPP 1585
Query: 117 EIYNVMRACWGHTPEERPSFRVLKEQLA 144
+ +VM CW + P +RP+F L LA
Sbjct: 1586 LLQSVMLYCWSYRPAQRPTFLHLLYLLA 1613
>UniRef50_O76385 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 903
Score = 136 bits (329), Expect = 2e-31
Identities = 63/155 (40%), Positives = 91/155 (58%), Gaps = 3/155 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAPP 58
+ YL + ++HRD+AARN LV + K+ DFGL RY+ DQ Y S GG K P+KW P
Sbjct: 698 LEYLSQKGFVHRDVAARNVLVHEGTACKIGDFGLCRYIYADQSQYKSKGG-KLPLKWMSP 756
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E + FS KSD+W+FG+L++EV T G PY + +V+ ++ G +EKP C
Sbjct: 757 EAIRHYEFSIKSDIWSFGILLFEVITLGGSPYPGMPPEDVLPFLEGGGRIEKPDNCPENF 816
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
Y+VM CW P++R F ++ QLA + + D
Sbjct: 817 YDVMMQCWNADPDDRIEFSDVRMQLATQLEDITED 851
>UniRef50_UPI0000DB7F8D Cluster: PREDICTED: similar to Cad96Ca
CG10244-PA; n=3; Endopterygota|Rep: PREDICTED: similar
to Cad96Ca CG10244-PA - Apis mellifera
Length = 657
Score = 136 bits (328), Expect = 3e-31
Identities = 64/137 (46%), Positives = 83/137 (60%), Gaps = 1/137 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ-YTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN L+ + KVADFG AR V +Q Y + PI+W PE
Sbjct: 482 MEYLASKGIIHRDLAARNILIDENRACKVADFGFARDVAANQIYERKSEGRLPIRWMAPE 541
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L FS KSD+W+FGVL+WE+ T G PY L +EV+ +++ G L++P+ C E+Y
Sbjct: 542 SLYDNIFSVKSDIWSFGVLIWEIVTLGSTPYPGLAAAEVMRRIKEGYRLDRPEHCKRELY 601
Query: 120 NVMRACWGHTPEERPSF 136
N+M CW P RPSF
Sbjct: 602 NIMYYCWDKDPACRPSF 618
>UniRef50_UPI000065FEDC Cluster: Activated CDC42 kinase 1 (EC
2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein
2).; n=3; Deuterostomia|Rep: Activated CDC42 kinase 1
(EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor
protein 2). - Takifugu rubripes
Length = 1127
Score = 135 bits (327), Expect = 3e-31
Identities = 63/146 (43%), Positives = 89/146 (60%), Gaps = 3/146 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD--DQYTSSGGTKFPIKWAPP 58
MAYLE+ +IHRDLAARN L+ + +K+ DFGL R + + + Y K P W P
Sbjct: 254 MAYLEQRRFIHRDLAARNILLASAHKIKIGDFGLMRALPNNHEHYVMQEHRKVPFAWCAP 313
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQR-GQVLEKPKGCINE 117
E L FS +D W FGV +WE+FT G+ P+ L S+++ K+ + G+ L KP+ C +
Sbjct: 314 ESLKTRTFSHATDTWMFGVTLWEMFTHGQEPWLGLNGSQILHKIDKEGERLPKPEDCPQD 373
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQL 143
IYNVM CW P++RP+F L+E L
Sbjct: 374 IYNVMLQCWAQKPDDRPTFVALREFL 399
>UniRef50_Q9YGM5 Cluster: Plasminogen related growth factor receptor
2; n=11; Clupeocephala|Rep: Plasminogen related growth
factor receptor 2 - Fugu rubripes (Japanese pufferfish)
(Takifugu rubripes)
Length = 1375
Score = 135 bits (327), Expect = 3e-31
Identities = 61/142 (42%), Positives = 91/142 (64%), Gaps = 3/142 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGG---TKFPIKWAP 57
M YL + ++HRDLAARNC++ + VKVADFG+AR + D +Y S K P+KW
Sbjct: 1179 MEYLAQKKFVHRDLAARNCMLDETYTVKVADFGMARDIYDKEYYSIQDHKQVKLPVKWMA 1238
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
E L +F+SKSDVW++G+LMWE+ T G PY + ++ + + +G+ L +P+ C N
Sbjct: 1239 IESLQTQKFTSKSDVWSYGILMWELLTRGASPYPDVDPYDITNYLLKGRRLPQPQFCPNT 1298
Query: 118 IYNVMRACWGHTPEERPSFRVL 139
+Y++M +CW P+ RPSF L
Sbjct: 1299 LYSIMLSCWDPEPDFRPSFSSL 1320
>UniRef50_Q5IJ68 Cluster: Trk-like receptor tyrosine kinase; n=1;
Aplysia californica|Rep: Trk-like receptor tyrosine
kinase - Aplysia californica (California sea hare)
Length = 865
Score = 135 bits (327), Expect = 3e-31
Identities = 61/147 (41%), Positives = 96/147 (65%), Gaps = 7/147 (4%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDEN-----VVKVADFGLARYVLDDQYTSSGGTKF-PIK 54
M YL ++HRDLA RNCLVG +VK++DFG++R + + Y GG++ PI+
Sbjct: 421 MRYLAAQRFVHRDLATRNCLVGTAPPGAGLLVKISDFGMSRDIYTNDYYKIGGSRMLPIR 480
Query: 55 WAPPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGC 114
W PE + + RF+ +SDVWA+GV++WE+F+ G+ PY +N EV+ + +G +L++P+ C
Sbjct: 481 WMSPEAIKYGRFTCESDVWAYGVVLWEIFSYGRQPYFGHSNEEVIHFLDQGILLQRPEDC 540
Query: 115 INEIYNVMRACWGHTPEERPSF-RVLK 140
+ +Y+VM CW P +R F R+LK
Sbjct: 541 PSTVYHVMLGCWKGDPRQRIVFDRLLK 567
>UniRef50_UPI00006A1E7A Cluster: Non-receptor tyrosine-protein
kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).;
n=3; Xenopus tropicalis|Rep: Non-receptor
tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38
negative kinase 1). - Xenopus tropicalis
Length = 673
Score = 135 bits (326), Expect = 5e-31
Identities = 61/139 (43%), Positives = 86/139 (61%), Gaps = 3/139 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV--LDDQYTSSGGTKFPIKWAPP 58
M YLE + +IHRDLA RN L+ E+V K+ DFGL R + D Y S K P W PP
Sbjct: 231 MKYLESYKFIHRDLATRNVLLTSEDVAKIGDFGLMRALGGHSDHYIMSTHRKIPFAWCPP 290
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRG-QVLEKPKGCINE 117
E L FS++SDVW FGV +WE+FT G+ P+ + +++ K+ R + LE+P C
Sbjct: 291 ESLKIGAFSNQSDVWMFGVTLWEMFTYGQEPWMGFSGKQILLKIDRDRETLERPDDCPQA 350
Query: 118 IYNVMRACWGHTPEERPSF 136
+Y VM+ CW + P++RP+F
Sbjct: 351 LYEVMKKCWIYEPDQRPTF 369
>UniRef50_Q4RXA0 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 11
SCAF14979, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1042
Score = 135 bits (326), Expect = 5e-31
Identities = 63/139 (45%), Positives = 85/139 (61%), Gaps = 4/139 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL +Y+HRDLAARN LV KV+DFGL+R + DD YT+ GG K PI+W
Sbjct: 795 MQYLSNMSYVHRDLAARNILVNSNLECKVSDFGLSRVLEDDDEGTYTTRGG-KIPIRWTA 853
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + + +F+S SDVW+FG++MWEV G+ PY ++N EV+ + L P C +
Sbjct: 854 PEAIAYRKFTSASDVWSFGIVMWEVMAFGERPYWDMSNHEVMKAINEAFRLPAPMDCPSA 913
Query: 118 IYNVMRACWGHTPEERPSF 136
IY +M CW H +RP F
Sbjct: 914 IYQLMLQCWQHDRSKRPRF 932
>UniRef50_Q9Y1X8 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 1193
Score = 135 bits (326), Expect = 5e-31
Identities = 64/148 (43%), Positives = 88/148 (59%), Gaps = 3/148 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARY--VLDDQYTSSGGTKFPIKWAPP 58
MAYLE +HRDLAARN LV +VK+ DFGL R V + Y ++GG P++W P
Sbjct: 955 MAYLEEKRMVHRDLAARNVLVHTPQLVKITDFGLTRIIDVGESHYKATGGM-VPLRWMAP 1013
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E + ++ KSDVW+FGV +WE+ T G++PY EV V+ GQ LE+P C +
Sbjct: 1014 ESIFLFEYTHKSDVWSFGVTIWEILTFGRLPYKGKNGKEVSQLVKNGQQLERPATCDANL 1073
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVI 146
Y+++ CW H +RPSF L L V+
Sbjct: 1074 YHLLEQCWLHDQTKRPSFSALSNSLNVM 1101
>UniRef50_Q6VU50 Cluster: Eph receptor; n=3; Endopterygota|Rep: Eph
receptor - Manduca sexta (Tobacco hawkmoth) (Tobacco
hornworm)
Length = 1011
Score = 135 bits (326), Expect = 5e-31
Identities = 62/146 (42%), Positives = 87/146 (59%), Gaps = 4/146 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV---LDDQYTSSGGTKFPIKWAP 57
M YL NYIHRDLAARN LV V K+ADFGL+R + D YT+ GG K P++W
Sbjct: 761 MQYLSEMNYIHRDLAARNVLVNSHLVCKIADFGLSREIESTADGAYTTRGG-KIPVRWTA 819
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + F +F+S SDVW+ G++ WEV + G+ PY +N +V+ +++G L P C
Sbjct: 820 PEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA 879
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQL 143
+Y +M CW RP+F + + L
Sbjct: 880 VYQLMLDCWQKERTHRPTFASIVKTL 905
>UniRef50_Q6TYB9 Cluster: Dauer abnormal formation-2 precursor; n=2;
Caenorhabditis briggsae|Rep: Dauer abnormal formation-2
precursor - Caenorhabditis briggsae
Length = 1807
Score = 135 bits (326), Expect = 5e-31
Identities = 62/146 (42%), Positives = 91/146 (62%), Gaps = 2/146 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
MAYLE + HRDLAARNC++ +VK+ DFG+AR + D Y SG P++W PE
Sbjct: 1334 MAYLESLKFCHRDLAARNCMIDKTELVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPE 1393
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKV-QRGQVLEKPKGCINEI 118
L +F SKSD+W+FGV+++E+ T G PY L+N EV++ + +V++KP C
Sbjct: 1394 SLKDGKFDSKSDIWSFGVVLYELITLGAQPYIGLSNDEVLNYIGMARKVIKKPDCCSEYW 1453
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLA 144
Y +M+ CW + P +RP+F L L+
Sbjct: 1454 YKIMKMCWRYAPRDRPTFLQLVHLLS 1479
>UniRef50_Q2LC18 Cluster: Tyrosine-protein kinase receptor; n=2;
Strongylocentrotus purpuratus|Rep: Tyrosine-protein
kinase receptor - Strongylocentrotus purpuratus (Purple
sea urchin)
Length = 1072
Score = 135 bits (326), Expect = 5e-31
Identities = 60/137 (43%), Positives = 84/137 (61%), Gaps = 1/137 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M++L Y+HRDL+ARNCLV E KVADFGLAR + D Y G PI+W PE
Sbjct: 823 MSFLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQSDYYRKERGGMLPIRWMAPE 882
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ F + SDVW+FG+L+WE+ T G++PY L+N E + ++ G VL P+ C ++
Sbjct: 883 SVKDGVFQASSDVWSFGILLWEMATLGELPYQGLSNEEAGEYIKGGNVLRPPENCPEKMQ 942
Query: 120 NVMRACWGHTPEERPSF 136
+M ACW + + RP F
Sbjct: 943 EIMMACWQYQEKLRPLF 959
>UniRef50_Q9V6K3 Cluster: Tyrosine-protein kinase transmembrane
receptor Ror2 precursor; n=2; Sophophora|Rep:
Tyrosine-protein kinase transmembrane receptor Ror2
precursor - Drosophila melanogaster (Fruit fly)
Length = 724
Score = 135 bits (326), Expect = 5e-31
Identities = 59/137 (43%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV-LDDQYTSSGGTKFPIKWAPPE 59
M YL ++HRDLA RNCL+ + VK+ADFGL+ + L D Y PI+W P E
Sbjct: 568 MLYLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKGDENDFIPIRWMPLE 627
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + +FS +SDVWA+G+ +WEVF+ PY LT+ EV+ ++ G VL P +Y
Sbjct: 628 SILYNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGNVLGCPDNTPLSVY 687
Query: 120 NVMRACWGHTPEERPSF 136
+MR CW P ERP F
Sbjct: 688 ALMRRCWNRKPSERPGF 704
>UniRef50_UPI0000DB6B52 Cluster: PREDICTED: similar to Ror
CG4926-PA; n=3; Endopterygota|Rep: PREDICTED: similar to
Ror CG4926-PA - Apis mellifera
Length = 529
Score = 134 bits (325), Expect = 6e-31
Identities = 65/157 (41%), Positives = 95/157 (60%), Gaps = 4/157 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL ++HRDLA RNCLVG + +VK+ADFG++R V D Y G PI+W PE
Sbjct: 330 MTYLSGQRFVHRDLACRNCLVGYDFIVKIADFGMSRDVYTCDYYKIKGSRLLPIRWMSPE 389
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTN---SEVVDKVQRGQVLEKPKGCIN 116
+ + RF+ +SDVW+FGV++WEV++ GK PY N S+VV + +G +L P+GC
Sbjct: 390 SVMYGRFTLESDVWSFGVVLWEVYSFGKQPYYGHNNEEVSKVVKLIFQGIMLIPPEGCPP 449
Query: 117 EIYNVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
+ +MR CW P++R F + E+L + + D
Sbjct: 450 FVCQIMRECWKTDPKDRIKFPEILERLEKVKVKTIQD 486
>UniRef50_Q9UF33 Cluster: Ephrin type-A receptor 6 precursor; n=57;
Euteleostomi|Rep: Ephrin type-A receptor 6 precursor -
Homo sapiens (Human)
Length = 1035
Score = 134 bits (325), Expect = 6e-31
Identities = 61/139 (43%), Positives = 86/139 (61%), Gaps = 4/139 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL Y+HRDLAARN LV V KV+DFGL+R + DD YT++GG K PI+W
Sbjct: 785 MKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGG-KIPIRWTA 843
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + + +FSS SD W++G++MWEV + G+ PY ++N +V+ ++ G L P GC
Sbjct: 844 PEAIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPAS 903
Query: 118 IYNVMRACWGHTPEERPSF 136
++ +M CW RP F
Sbjct: 904 LHQLMLHCWQKERNHRPKF 922
>UniRef50_UPI000069DB6A Cluster: Ephrin type-A receptor 6 precursor
(EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2)
(EPH homology kinase 2).; n=2; Xenopus tropicalis|Rep:
Ephrin type-A receptor 6 precursor (EC 2.7.10.1)
(Tyrosine-protein kinase receptor EHK-2) (EPH homology
kinase 2). - Xenopus tropicalis
Length = 952
Score = 134 bits (324), Expect = 8e-31
Identities = 62/139 (44%), Positives = 86/139 (61%), Gaps = 4/139 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL Y+HRDLAARN LV V KV+DFGL+R + DD YT++GG K PI+W
Sbjct: 701 MKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPDAAYTTTGG-KIPIRWTA 759
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + F +FSS SD W++G++MWEV + G+ PY ++N +V+ ++ G L P GC
Sbjct: 760 PEAIAFRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPVS 819
Query: 118 IYNVMRACWGHTPEERPSF 136
++ +M CW RP F
Sbjct: 820 LHQLMLHCWQKDRNIRPKF 838
>UniRef50_Q10656-2 Cluster: Isoform b of Q10656 ; n=4;
Caenorhabditis|Rep: Isoform b of Q10656 - Caenorhabditis
elegans
Length = 988
Score = 134 bits (324), Expect = 8e-31
Identities = 62/144 (43%), Positives = 90/144 (62%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV-LDDQYTSSGGTKFPIKWAPPE 59
M +L IHRDLAARN LVGD +V+K++DFGL+R V +D Y G + PIKW E
Sbjct: 733 MNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALE 792
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L+ ++ +SDVW++GVL+WE+ T G PY + E+ ++ G +E P C E+Y
Sbjct: 793 ALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVY 852
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
++M +CW EERPSF+ + + L
Sbjct: 853 HLMCSCWREKLEERPSFKTIVDYL 876
>UniRef50_Q4SC90 Cluster: Chromosome undetermined SCAF14659, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF14659, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 712
Score = 134 bits (324), Expect = 8e-31
Identities = 63/139 (45%), Positives = 87/139 (62%), Gaps = 4/139 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL +Y+HRDLAARN LV + KV+DFGL+R + DD YT+SGG K PI+W
Sbjct: 465 MKYLSDMSYVHRDLAARNILVNNTLECKVSDFGLSRVLEDDPEGTYTTSGG-KIPIRWTA 523
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + + +F+S SDVW+FG++MWEV G+ PY ++N EV+ + L P C +
Sbjct: 524 PEAIAYRKFASASDVWSFGIVMWEVMAFGERPYWDMSNHEVMKAINEAFRLPAPMDCPSA 583
Query: 118 IYNVMRACWGHTPEERPSF 136
+Y +M CW H +RP F
Sbjct: 584 VYQLMLQCWLHDRAKRPRF 602
>UniRef50_Q4JDD5 Cluster: Tyrosine-protein kinase receptor; n=5; Danio
rerio|Rep: Tyrosine-protein kinase receptor - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 1272
Score = 134 bits (324), Expect = 8e-31
Identities = 65/151 (43%), Positives = 94/151 (62%), Gaps = 2/151 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDD-QYTSSGGTKFPIKWAPPE 59
M +L IHRDLAARN L+ + NVVK+ DFGLAR + D Y +G + P+KW PE
Sbjct: 991 MEFLASRKCIHRDLAARNILLSNNNVVKICDFGLARDLYKDPDYVRNGDARLPLKWMAPE 1050
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPY-GRLTNSEVVDKVQRGQVLEKPKGCINEI 118
+ F+++SDVW++GVL+WE+F+ G PY G + E +++ G + P+ EI
Sbjct: 1051 SIFDKVFTTQSDVWSYGVLLWEIFSLGASPYPGLNMDEEFCRRLKHGTRMCSPQYSTPEI 1110
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQS 149
Y++M ACW + PE+RPSF L E L + Q+
Sbjct: 1111 YSIMCACWENNPEDRPSFTTLVEILGDLLQT 1141
>UniRef50_Q1JUB8 Cluster: Fibroblast growth factor receptor; n=2;
Obtectomera|Rep: Fibroblast growth factor receptor -
Bombyx mori (Silk moth)
Length = 856
Score = 134 bits (324), Expect = 8e-31
Identities = 64/144 (44%), Positives = 86/144 (59%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV-LDDQYTSSGGTKFPIKWAPPE 59
M YL IHRD AARN LV D+ V+K+ADFGLA+ V +D Y + P++W PE
Sbjct: 671 MEYLASRRCIHRDSAARNVLVSDDCVLKIADFGLAKDVHSNDYYRKKTEGRLPVRWMAPE 730
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L F++++DVW+FGVL+WE+ T G PY + + + G +EKP C EIY
Sbjct: 731 SLYHKVFTTQTDVWSFGVLLWEIMTLGGTPYPTVPGQYMYQHLSAGHRMEKPPCCSLEIY 790
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+MR CW +P +RPSF L E L
Sbjct: 791 MLMRECWSFSPGDRPSFTELVEDL 814
>UniRef50_Q17J18 Cluster: Tyrosine-protein kinase; n=4;
Endopterygota|Rep: Tyrosine-protein kinase - Aedes
aegypti (Yellowfever mosquito)
Length = 959
Score = 134 bits (324), Expect = 8e-31
Identities = 66/145 (45%), Positives = 91/145 (62%), Gaps = 2/145 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGT-KFPIKWAPPE 59
M +L IHRDLAARN LV D V+K+ADFGLAR + +Y T K PI+W PE
Sbjct: 758 MEHLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDIHSQEYYRKTTTGKLPIRWMAPE 817
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRL-TNSEVVDKVQRGQVLEKPKGCINEI 118
L + S+SDVW+FGVL+WE+ T G PY + T +++ +++G+ LE+P C +I
Sbjct: 818 SLEEKFYDSQSDVWSFGVLLWEIMTLGGNPYSSIPTWDNLLEHLKKGKRLEQPPLCSIDI 877
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y MR CW + PEERP+F + + L
Sbjct: 878 YLFMRECWHYRPEERPTFSEIVQHL 902
>UniRef50_Q10656 Cluster: Myoblast growth factor receptor egl-15
precursor; n=7; Caenorhabditis elegans|Rep: Myoblast
growth factor receptor egl-15 precursor - Caenorhabditis
elegans
Length = 1040
Score = 134 bits (324), Expect = 8e-31
Identities = 62/144 (43%), Positives = 90/144 (62%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV-LDDQYTSSGGTKFPIKWAPPE 59
M +L IHRDLAARN LVGD +V+K++DFGL+R V +D Y G + PIKW E
Sbjct: 785 MNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALE 844
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L+ ++ +SDVW++GVL+WE+ T G PY + E+ ++ G +E P C E+Y
Sbjct: 845 ALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVY 904
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
++M +CW EERPSF+ + + L
Sbjct: 905 HLMCSCWREKLEERPSFKTIVDYL 928
>UniRef50_A7RZ71 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 624
Score = 134 bits (323), Expect = 1e-30
Identities = 61/143 (42%), Positives = 91/143 (63%), Gaps = 1/143 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN LVG++ V+K+ADFGLAR V D D Y + + PIKW E
Sbjct: 466 MEYLSFKKCIHRDLAARNILVGEDYVMKIADFGLARNVRDMDYYRKATDGRLPIKWLAIE 525
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++++SDVW FG+L+WE+FT G PY + ++ + ++ G ++ P+ C +++Y
Sbjct: 526 ALFDRVYTTQSDVWTFGILLWEIFTLGGSPYPGIPVEKLFELLKSGYRMQMPQKCPDKMY 585
Query: 120 NVMRACWGHTPEERPSFRVLKEQ 142
++M +CW P RPSF L+ +
Sbjct: 586 DIMLSCWNENPNARPSFTELRAE 608
>UniRef50_A3EXK4 Cluster: Fibroblast growth factor receptor a; n=1;
Nematostella vectensis|Rep: Fibroblast growth factor
receptor a - Nematostella vectensis
Length = 441
Score = 134 bits (323), Expect = 1e-30
Identities = 61/143 (42%), Positives = 91/143 (63%), Gaps = 1/143 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN LVG++ V+K+ADFGLAR V D D Y + + PIKW E
Sbjct: 251 MEYLSFKKCIHRDLAARNILVGEDYVMKIADFGLARNVRDMDYYRKATDGRLPIKWLAIE 310
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++++SDVW FG+L+WE+FT G PY + ++ + ++ G ++ P+ C +++Y
Sbjct: 311 ALFDRVYTTQSDVWTFGILLWEIFTLGGSPYPGIPVEKLFELLKSGYRMQMPQKCPDKMY 370
Query: 120 NVMRACWGHTPEERPSFRVLKEQ 142
++M +CW P RPSF L+ +
Sbjct: 371 DIMLSCWNENPNARPSFTELRAE 393
>UniRef50_Q07407 Cluster: Fibroblast growth factor receptor homolog
1 precursor; n=3; Sophophora|Rep: Fibroblast growth
factor receptor homolog 1 precursor - Drosophila
melanogaster (Fruit fly)
Length = 729
Score = 134 bits (323), Expect = 1e-30
Identities = 65/151 (43%), Positives = 91/151 (60%), Gaps = 2/151 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL IHRDLAARN LV D+ V+K+ADFGLAR + D Y + + PIKW PE
Sbjct: 544 MDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPE 603
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNS-EVVDKVQRGQVLEKPKGCINEI 118
L + SKSDVW++G+L+WE+ T G+ PY + ++ E+ + GQ +EKP C I
Sbjct: 604 SLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNI 663
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQS 149
Y +MR CW ++RP F + E + + Q+
Sbjct: 664 YILMRQCWHFNADDRPPFTEIVEYMDKLLQT 694
>UniRef50_Q15375 Cluster: Ephrin type-A receptor 7 precursor; n=51;
Euteleostomi|Rep: Ephrin type-A receptor 7 precursor -
Homo sapiens (Human)
Length = 998
Score = 134 bits (323), Expect = 1e-30
Identities = 60/139 (43%), Positives = 87/139 (62%), Gaps = 4/139 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ---YTSSGGTKFPIKWAP 57
M YL Y+HRDLAARN LV V KV+DFGL+R + DD YT++GG K P++W
Sbjct: 746 MRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGG-KIPVRWTA 804
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + + +F+S SDVW++G++MWEV + G+ PY ++N +V+ ++ G L P C
Sbjct: 805 PEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAG 864
Query: 118 IYNVMRACWGHTPEERPSF 136
++ +M CW ERP F
Sbjct: 865 LHQLMLDCWQKERAERPKF 883
>UniRef50_Q10925-2 Cluster: Isoform b of Q10925 ; n=2;
Caenorhabditis elegans|Rep: Isoform b of Q10925 -
Caenorhabditis elegans
Length = 1130
Score = 133 bits (322), Expect = 1e-30
Identities = 62/146 (42%), Positives = 88/146 (60%), Gaps = 3/146 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVG-DENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAP 57
+ +LE + +HRD+AARN L+ DE VK+ DFGL R + +++ YT + K P W P
Sbjct: 218 LQFLESKHCVHRDVAARNILLARDERTVKICDFGLMRALKENEQMYTMAPQKKVPFAWCP 277
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE L +FS SDVW++GV +WEVFT G+ P+ +V+ + G+ LEKPK C
Sbjct: 278 PEALRHRKFSHASDVWSYGVTIWEVFTFGEEPWVGCRAIDVLKNIDAGERLEKPKYCSER 337
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQL 143
IY +M+ CW P ER F ++E L
Sbjct: 338 IYQIMKNCWKFNPAERCKFGAIREDL 363
>UniRef50_Q4SFK0 Cluster: Chromosome 7 SCAF14601, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 7
SCAF14601, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 993
Score = 133 bits (322), Expect = 1e-30
Identities = 61/147 (41%), Positives = 89/147 (60%), Gaps = 4/147 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL----DDQYTSSGGTKFPIKWA 56
M YL +Y+HRDLAARN L+ V KV+DFGL+R++ D YTSS G K PI+W
Sbjct: 740 MKYLSEMSYVHRDLAARNILINSNLVCKVSDFGLSRFLQENSSDPTYTSSLGGKIPIRWT 799
Query: 57 PPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCIN 116
PE + F +F+S SDVW++G++MWEV + G+ PY ++N +V++ +++ L P C
Sbjct: 800 APEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPT 859
Query: 117 EIYNVMRACWGHTPEERPSFRVLKEQL 143
++ +M CW RP F L L
Sbjct: 860 HLHQLMLDCWQKDRSARPRFADLVSAL 886
>UniRef50_Q4SFJ9 Cluster: Chromosome 7 SCAF14601, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 7 SCAF14601, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 761
Score = 133 bits (322), Expect = 1e-30
Identities = 61/147 (41%), Positives = 89/147 (60%), Gaps = 4/147 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL----DDQYTSSGGTKFPIKWA 56
M YL +Y+HRDLAARN L+ V KV+DFGL+R++ D YTSS G K PI+W
Sbjct: 522 MKYLSEMSYVHRDLAARNILINSNLVCKVSDFGLSRFLQENSSDPTYTSSLGGKIPIRWT 581
Query: 57 PPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCIN 116
PE + F +F+S SDVW++G++MWEV + G+ PY ++N +V++ +++ L P C
Sbjct: 582 APEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDCPT 641
Query: 117 EIYNVMRACWGHTPEERPSFRVLKEQL 143
++ +M CW RP F L L
Sbjct: 642 HLHQLMLDCWQKDRSARPRFADLVSAL 668
>UniRef50_Q9Y1Z4 Cluster: Protein tyrosine kinase 37; n=1; Hydra
magnipapillata|Rep: Protein tyrosine kinase 37 - Hydra
magnipapillata (Hydra)
Length = 527
Score = 133 bits (322), Expect = 1e-30
Identities = 57/117 (48%), Positives = 79/117 (67%)
Query: 20 LVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNFTRFSSKSDVWAFGVLM 79
LVG+ +++KVADFGLAR +++D Y + G KFPIKW PE L + +FSSKSDVWAFGVLM
Sbjct: 1 LVGENHLIKVADFGLARSMMNDYYKAHSGAKFPIKWTSPEALAYNKFSSKSDVWAFGVLM 60
Query: 80 WEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYNVMRACWGHTPEERPSF 136
WE+ G PY ++V +++G +E P+GC + Y +M CW P +RP+F
Sbjct: 61 WEIVKYGASPYPGHDLNQVYSLIEQGYRMECPEGCPDAAYELMLDCWKWNPNDRPTF 117
>UniRef50_Q9VLQ8 Cluster: CG8222-PA, isoform A; n=8; Sophophora|Rep:
CG8222-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 1509
Score = 133 bits (322), Expect = 1e-30
Identities = 66/146 (45%), Positives = 90/146 (61%), Gaps = 2/146 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
M YL +H DLAARN L+ ++NVVK+ DFGLAR + D Y S K PIKW E
Sbjct: 1117 MDYLSSKKVLHGDLAARNILLCEDNVVKICDFGLARSMYRGDNYKKSENGKLPIKWLALE 1176
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPY-GRLTNSEVVDKVQRGQVLEKPKGCINEI 118
L+ FS+ SDVW++G+++WE+F+ KVPY G N E+ +K+ G +EKPK E+
Sbjct: 1177 SLSDHVFSTYSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKLNDGYRMEKPKFANQEL 1236
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLA 144
Y +M CW PE RP F L+++ A
Sbjct: 1237 YEIMLECWRKNPESRPLFAELEKRFA 1262
>UniRef50_Q8T4M0 Cluster: VEGFR-A splice form A; n=4; Diptera|Rep:
VEGFR-A splice form A - Drosophila melanogaster (Fruit
fly)
Length = 1474
Score = 133 bits (322), Expect = 1e-30
Identities = 66/146 (45%), Positives = 90/146 (61%), Gaps = 2/146 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
M YL +H DLAARN L+ ++NVVK+ DFGLAR + D Y S K PIKW E
Sbjct: 1082 MDYLSSKKVLHGDLAARNILLCEDNVVKICDFGLARSMYRGDNYKKSENGKLPIKWLALE 1141
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPY-GRLTNSEVVDKVQRGQVLEKPKGCINEI 118
L+ FS+ SDVW++G+++WE+F+ KVPY G N E+ +K+ G +EKPK E+
Sbjct: 1142 SLSDHVFSTYSDVWSYGIVLWEMFSLAKVPYPGIDPNQELFNKLNDGYRMEKPKFANQEL 1201
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLA 144
Y +M CW PE RP F L+++ A
Sbjct: 1202 YEIMLECWRKNPESRPLFAELEKRFA 1227
>UniRef50_Q7YZH7 Cluster: MBRTK2; n=1; Monosiga brevicollis|Rep:
MBRTK2 - Monosiga brevicollis
Length = 759
Score = 133 bits (322), Expect = 1e-30
Identities = 61/143 (42%), Positives = 88/143 (61%), Gaps = 1/143 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M++LER N IHRDLAARN L+ K+ DFGLAR + ++ Y ++ TK P+KW PE
Sbjct: 481 MSFLERKNVIHRDLAARNVLLSQSLACKICDFGLARSIENEDYETTA-TKLPVKWMAPES 539
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
L + ++SKSDVW+FGV MWE+F+ G PY + N +++ + G L KP+ +
Sbjct: 540 LGYRIYTSKSDVWSFGVTMWEIFSLGGTPYVKHRNVDILSLLADGYRLPKPRQAPGQADA 599
Query: 121 VMRACWGHTPEERPSFRVLKEQL 143
+ R CW H + RP+F L + L
Sbjct: 600 IARMCWMHEADNRPTFLELVDLL 622
>UniRef50_Q5D184 Cluster: Ephrin receptor; n=2; Apocrita|Rep: Ephrin
receptor - Apis mellifera (Honeybee)
Length = 996
Score = 133 bits (322), Expect = 1e-30
Identities = 63/152 (41%), Positives = 90/152 (59%), Gaps = 4/152 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV---LDDQYTSSGGTKFPIKWAP 57
M YL NY+HRDLAARN LV V K+ADFGL+R + + YT+ GG K P++W
Sbjct: 748 MQYLAEMNYVHRDLAARNVLVNAALVCKIADFGLSREIESATEGAYTTRGG-KIPVRWTA 806
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE + F +F+S SDVW+ G++ WEV + G+ PY +N +V+ +++G L P C
Sbjct: 807 PEAIAFRKFTSASDVWSMGIVCWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA 866
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQS 149
IY +M CW RP+F L + L + +S
Sbjct: 867 IYQLMLDCWQKERTHRPTFANLTQTLDKLIRS 898
>UniRef50_O45232 Cluster: Putative uncharacterized protein ark-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein ark-1 - Caenorhabditis elegans
Length = 1043
Score = 133 bits (322), Expect = 1e-30
Identities = 61/141 (43%), Positives = 96/141 (68%), Gaps = 5/141 (3%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARY--VLDDQYTS--SGGTKFPIKWA 56
M+YLE IHRDLAARN LV +VK++DFGL+R + +D Y S + K PI W
Sbjct: 229 MSYLELQRLIHRDLAARNVLVFSPKLVKISDFGLSRSLGIGEDYYRSEFTPNLKLPIAWC 288
Query: 57 PPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQR-GQVLEKPKGCI 115
PE +NF +F+SKSDVWA+GV +WE+F+ G++P+ + +++++ V R ++L +PK C
Sbjct: 289 APECINFLKFTSKSDVWAYGVTIWEMFSYGEMPWKGRSGAQILELVDRKKELLTRPKACP 348
Query: 116 NEIYNVMRACWGHTPEERPSF 136
+IY++++ W H ++RP+F
Sbjct: 349 EDIYDMLKETWTHQVQDRPTF 369
>UniRef50_P08581 Cluster: Hepatocyte growth factor receptor precursor;
n=81; Tetrapoda|Rep: Hepatocyte growth factor receptor
precursor - Homo sapiens (Human)
Length = 1390
Score = 133 bits (322), Expect = 1e-30
Identities = 63/156 (40%), Positives = 95/156 (60%), Gaps = 3/156 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTS---SGGTKFPIKWAP 57
M YL ++HRDLAARNC++ ++ VKVADFGLAR + D +Y S G K P+KW
Sbjct: 1192 MKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMA 1251
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
E L +F++KSDVW+FGV++WE+ T G PY + ++ + +G+ L +P+ C +
Sbjct: 1252 LESLQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDP 1311
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
+Y VM CW E RPSF L +++ I + + +
Sbjct: 1312 LYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
>UniRef50_Q10925 Cluster: Probable tyrosine-protein kinase kin-25;
n=2; Caenorhabditis|Rep: Probable tyrosine-protein
kinase kin-25 - Caenorhabditis elegans
Length = 1237
Score = 133 bits (322), Expect = 1e-30
Identities = 62/146 (42%), Positives = 88/146 (60%), Gaps = 3/146 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVG-DENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAP 57
+ +LE + +HRD+AARN L+ DE VK+ DFGL R + +++ YT + K P W P
Sbjct: 218 LQFLESKHCVHRDVAARNILLARDERTVKICDFGLMRALKENEQMYTMAPQKKVPFAWCP 277
Query: 58 PEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINE 117
PE L +FS SDVW++GV +WEVFT G+ P+ +V+ + G+ LEKPK C
Sbjct: 278 PEALRHRKFSHASDVWSYGVTIWEVFTFGEEPWVGCRAIDVLKNIDAGERLEKPKYCSER 337
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQL 143
IY +M+ CW P ER F ++E L
Sbjct: 338 IYQIMKNCWKFNPAERCKFGAIREDL 363
>UniRef50_UPI000065E2FA Cluster: Homolog of Homo sapiens "Tyrosine
kinase, non-recepTor, 2 isoform 1; n=1; Takifugu
rubripes|Rep: Homolog of Homo sapiens "Tyrosine kinase,
non-recepTor, 2 isoform 1 - Takifugu rubripes
Length = 767
Score = 133 bits (321), Expect = 2e-30
Identities = 66/142 (46%), Positives = 83/142 (58%), Gaps = 3/142 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD--DQYTSSGGTKFPIKWAPP 58
M YLE IHRDLAARN L+ +VK+ DFGL R + D Y S + P W P
Sbjct: 251 MDYLETRRLIHRDLAARNILLASREMVKIGDFGLMRGLSQEVDHYVMSAHRRIPFAWCAP 310
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQR-GQVLEKPKGCINE 117
E L FS SDVW FGV MWE+FT + P+ LT +++ +V+R G+ LEKP C E
Sbjct: 311 ESLRVGSFSHSSDVWMFGVTMWEMFTYCEEPWFGLTGRQILWRVEREGERLEKPPDCPQE 370
Query: 118 IYNVMRACWGHTPEERPSFRVL 139
+Y VMR CW P +RP+F L
Sbjct: 371 LYVVMRKCWACNPNDRPNFSQL 392
>UniRef50_Q9Y1Y0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 472
Score = 133 bits (321), Expect = 2e-30
Identities = 67/155 (43%), Positives = 93/155 (60%), Gaps = 5/155 (3%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQ--YTSSGGTKFPIKWAPP 58
M Y+ +HRDLAARN LVG+ V KVADFGL R + +D Y S PIKW PP
Sbjct: 319 MHYISEKGLVHRDLAARNVLVGENEVCKVADFGLLRELPEDGDIYFSMHNIPCPIKWMPP 378
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E ++ +FS SDVW+FGVLMWE+F K PY ++N E V +G L P+G + +
Sbjct: 379 ESIDGGKFSVASDVWSFGVLMWEMFNPSKPPYQGMSNMECAVAVCKGYRLPLPRGIPSIL 438
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQSVLAD 153
VM +CW P +RP F ++ L++++ VL++
Sbjct: 439 AKVMESCWHQNPHKRPGFLII---LSLLTTKVLSE 470
>UniRef50_Q8IQ00 Cluster: CG3277-PB, isoform B; n=3; Sophophora|Rep:
CG3277-PB, isoform B - Drosophila melanogaster (Fruit
fly)
Length = 808
Score = 133 bits (321), Expect = 2e-30
Identities = 58/144 (40%), Positives = 90/144 (62%), Gaps = 3/144 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
M +LE HRDLAARN L+ +K++DFGL+R+ + YT++ K P++W E
Sbjct: 643 MRFLEEQEITHRDLAARNVLIDSNKTLKISDFGLSRHGI---YTNTRTRKLPLRWLSIEA 699
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+ +SSKSD+WA+GV++WE+ T G PY ++N E++ + G LE+P+ C ++Y
Sbjct: 700 IRENVYSSKSDIWAYGVVLWEIGTLGASPYPTISNDELIPFLMAGNRLERPEICTPQVYT 759
Query: 121 VMRACWGHTPEERPSFRVLKEQLA 144
+M CW PEERP+F L + L+
Sbjct: 760 IMLQCWLEEPEERPTFDALYKVLS 783
>UniRef50_Q7YZW6 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 276
Score = 133 bits (321), Expect = 2e-30
Identities = 59/147 (40%), Positives = 92/147 (62%), Gaps = 3/147 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEV 60
MA+LE IHRDLAARN LVG V+K++DFG++R Y P++W PE
Sbjct: 117 MAHLESVGIIHRDLAARNILVGTGKVLKISDFGMSR---PGVYIKMSKGVIPLRWLSPEA 173
Query: 61 LNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIYN 120
+ +S+KSDVWAFGVL+WE+ T G PY + + ++++++ G LE+P C +++Y
Sbjct: 174 IKDNTYSNKSDVWAFGVLLWEIATLGGFPYNNVADKDILNQLTEGMRLEQPAKCSDDMYI 233
Query: 121 VMRACWGHTPEERPSFRVLKEQLAVIS 147
+M++CW E+RPSF + ++ I+
Sbjct: 234 LMKSCWNLKAEDRPSFLAILSKIEQIA 260
>UniRef50_Q7PT15 Cluster: ENSANGP00000009263; n=2; Culicidae|Rep:
ENSANGP00000009263 - Anopheles gambiae str. PEST
Length = 1306
Score = 133 bits (321), Expect = 2e-30
Identities = 66/142 (46%), Positives = 87/142 (61%), Gaps = 6/142 (4%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARY--VLDDQYTSSGGT--KFPIKWA 56
M YLE +IHRDLAARN LV +N VK++DFGL+R V D Y ++ K PI W
Sbjct: 235 MMYLENKRFIHRDLAARNILVFSKNKVKISDFGLSRALGVGKDYYQTNFNVNLKLPIAWC 294
Query: 57 PPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRG--QVLEKPKGC 114
PE +NF RF+ SDVWAFGV +WE+F+ G P+ LT ++++ + Q LEKP+ C
Sbjct: 295 APECINFLRFTHASDVWAFGVCLWEIFSYGFQPWAALTGHQILEAIDEPHYQRLEKPECC 354
Query: 115 INEIYNVMRACWGHTPEERPSF 136
E Y +M CW H +RP F
Sbjct: 355 PKEYYALMLKCWQHDAAKRPKF 376
>UniRef50_Q4H3M3 Cluster: Ephrin receptor like protein; n=1; Ciona
intestinalis|Rep: Ephrin receptor like protein - Ciona
intestinalis (Transparent sea squirt)
Length = 1085
Score = 133 bits (321), Expect = 2e-30
Identities = 64/155 (41%), Positives = 95/155 (61%), Gaps = 2/155 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYT-SSGGTKFPIKWAPPE 59
MAYL + Y+HRDLAARN L+ +E V KVADFGL R++ + + T ++ G K ++W PE
Sbjct: 836 MAYLSKMCYVHRDLAARNVLINNELVCKVADFGLIRHIGEKKSTVNTKGGKISLRWTAPE 895
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + +S SDVW+FGV WEV T G+ PY LTN +V+ + G L P+ C + ++
Sbjct: 896 AVAYQAYSQASDVWSFGVFAWEVITYGEKPYWSLTNQQVLQAINDGYRLPAPEDCPSVLH 955
Query: 120 NVMRACWGHTPEERPSFRVLKEQL-AVISQSVLAD 153
+M CW RP+F + +L A+I+Q + D
Sbjct: 956 QLMLECWHRDKNTRPTFEQVVTRLDAMINQRGVLD 990
>UniRef50_O97191 Cluster: Tyrosine-protein kinase receptor; n=1;
Geodia cydonium|Rep: Tyrosine-protein kinase receptor -
Geodia cydonium (Sponge)
Length = 570
Score = 133 bits (321), Expect = 2e-30
Identities = 66/144 (45%), Positives = 86/144 (59%), Gaps = 2/144 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YL +++HRDLAARNC+V E V+VADFGL+R V D Y T P+KW PE
Sbjct: 398 MEYLSNSSFVHRDLAARNCMVSGELTVRVADFGLSRDVYSKDYYRMGTKTMLPVKWMAPE 457
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L F+ KSDVW+FGV+ WEVF+ PY + N E+ D + G+ L+ P+ C EIY
Sbjct: 458 SLADNIFTVKSDVWSFGVVCWEVFSL-VAPYPGIGNHEMSDYIGGGRRLKIPRLCPREIY 516
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+M CW +RP+F L QL
Sbjct: 517 ELMEQCWNEESNKRPNFSELVSQL 540
>UniRef50_P17948 Cluster: Vascular endothelial growth factor receptor
1 precursor; n=48; cellular organisms|Rep: Vascular
endothelial growth factor receptor 1 precursor - Homo
sapiens (Human)
Length = 1338
Score = 133 bits (321), Expect = 2e-30
Identities = 63/151 (41%), Positives = 91/151 (60%), Gaps = 2/151 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDD-QYTSSGGTKFPIKWAPPE 59
M +L IHRDLAARN L+ + NVVK+ DFGLAR + + Y G T+ P+KW PE
Sbjct: 1010 MEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPE 1069
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPY-GRLTNSEVVDKVQRGQVLEKPKGCINEI 118
+ +S+KSDVW++GVL+WE+F+ G PY G + + +++ G + P+ EI
Sbjct: 1070 SIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEI 1129
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLAVISQS 149
Y +M CW P+ERP F L E+L + Q+
Sbjct: 1130 YQIMLDCWHRDPKERPRFAELVEKLGDLLQA 1160
>UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2;
Sophophora|Rep: Tyrosine-protein kinase shark -
Drosophila melanogaster (Fruit fly)
Length = 939
Score = 133 bits (321), Expect = 2e-30
Identities = 61/146 (41%), Positives = 91/146 (62%), Gaps = 2/146 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL--DDQYTSSGGTKFPIKWAPP 58
M YLE +++HRDLAARN L+ + K++DFG++R + +Y + G ++PI+W P
Sbjct: 777 MHYLESQHFVHRDLAARNILLTARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAP 836
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E N FS SDVW+FGV +WE+F+ G PYG ++N + + V G+ L +P C I
Sbjct: 837 ESFNLGIFSHASDVWSFGVTIWEMFSLGAPPYGEISNVDAIKLVDSGERLPQPNLCPAYI 896
Query: 119 YNVMRACWGHTPEERPSFRVLKEQLA 144
Y VM++CW P++RP+F L E A
Sbjct: 897 YAVMQSCWKERPKDRPTFVYLTEFFA 922
>UniRef50_P79749 Cluster: Beta-type platelet-derived growth factor
receptor precursor; n=9; Clupeocephala|Rep: Beta-type
platelet-derived growth factor receptor precursor - Fugu
rubripes (Japanese pufferfish) (Takifugu rubripes)
Length = 1048
Score = 133 bits (321), Expect = 2e-30
Identities = 60/141 (42%), Positives = 88/141 (62%), Gaps = 2/141 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
M +L N +HRDLAARN L+ + +VK+ DFGLAR ++ D Y S G T P+KW PE
Sbjct: 809 MEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMHDSNYISKGSTFLPLKWMAPE 868
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEV-VDKVQRGQVLEKPKGCINEI 118
+ +++ SDVW++G+L+WE+FT G PY L +E+ ++RG + KP +E+
Sbjct: 869 SIFHNLYTTLSDVWSYGILLWEIFTLGGTPYPDLPMNELFYSPLKRGYRMAKPAHASDEV 928
Query: 119 YNVMRACWGHTPEERPSFRVL 139
Y +M+ CW T E+RP F L
Sbjct: 929 YEIMKRCWDETFEKRPDFSFL 949
>UniRef50_Q9PVZ4 Cluster: Insulin receptor precursor (EC 2.7.10.1)
(IR) (Xe-InsR) (XTK-1b) [Contains: Insulin receptor
subunit alpha; Insulin receptor subunit beta]; n=6;
Euteleostomi|Rep: Insulin receptor precursor (EC
2.7.10.1) (IR) (Xe-InsR) (XTK-1b) [Contains: Insulin
receptor subunit alpha; Insulin receptor subunit beta] -
Xenopus laevis (African clawed frog)
Length = 1362
Score = 133 bits (321), Expect = 2e-30
Identities = 57/144 (39%), Positives = 90/144 (62%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKF-PIKWAPPE 59
MAYL ++HRDLAARNC+V D+ VK+ DFG+ R + + Y GG P++W PE
Sbjct: 1136 MAYLNAKKFVHRDLAARNCMVADDYAVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPE 1195
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L F++ SDVW+FGV++WE+ + + PY L+N +V+ V G L+ P+ C ++
Sbjct: 1196 SLKDGVFTAFSDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDHPENCPPRLH 1255
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
++M+ CW + P+ RP+F + + L
Sbjct: 1256 SLMQMCWQYNPKMRPTFLEIIDML 1279
>UniRef50_P09208 Cluster: Insulin-like receptor precursor (EC
2.7.10.1) (DIR) (DInr) (dIRH) [Contains: Insulin-like
receptor subunit alpha; Insulin-like receptor subunit
beta 1; Insulin-like receptor subunit beta 2]; n=15;
Eumetazoa|Rep: Insulin-like receptor precursor (EC
2.7.10.1) (DIR) (DInr) (dIRH) [Contains: Insulin-like
receptor subunit alpha; Insulin-like receptor subunit
beta 1; Insulin-like receptor subunit beta 2] -
Drosophila melanogaster (Fruit fly)
Length = 2144
Score = 133 bits (321), Expect = 2e-30
Identities = 61/138 (44%), Positives = 88/138 (63%), Gaps = 3/138 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK--FPIKWAPP 58
MAYL ++HRDLAARNC+V D+ VK+ DFG+ R + + Y G TK P++W PP
Sbjct: 1507 MAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKG-TKGLLPVRWMPP 1565
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E L +SS SDV++FGV++WE+ T PY L+N +V+ V G V+E+P+ C + +
Sbjct: 1566 ESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFL 1625
Query: 119 YNVMRACWGHTPEERPSF 136
+ +M+ CW H RPSF
Sbjct: 1626 HKLMQRCWHHRSSARPSF 1643
>UniRef50_P14616 Cluster: Insulin receptor-related protein precursor
(EC 2.7.10.1) (IRR) (IR- related receptor) [Contains:
Insulin receptor-related protein alpha chain; Insulin
receptor-related protein beta chain]; n=14; Eutheria|Rep:
Insulin receptor-related protein precursor (EC 2.7.10.1)
(IRR) (IR- related receptor) [Contains: Insulin
receptor-related protein alpha chain; Insulin
receptor-related protein beta chain] - Homo sapiens
(Human)
Length = 1297
Score = 133 bits (321), Expect = 2e-30
Identities = 60/137 (43%), Positives = 85/137 (62%), Gaps = 1/137 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTKF-PIKWAPPE 59
MAYL + ++HRDLAARNC+V + VK+ DFG+ R V + Y GG P++W PE
Sbjct: 1103 MAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPE 1162
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L F++ SDVW+FGV++WE+ T + PY L+N +V+ V G VLE+ +GC ++
Sbjct: 1163 SLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQLQ 1222
Query: 120 NVMRACWGHTPEERPSF 136
+M CW P RPSF
Sbjct: 1223 ELMSRCWQPNPRLRPSF 1239
>UniRef50_UPI0000E47549 Cluster: PREDICTED: similar to Cek8; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Cek8 - Strongylocentrotus purpuratus
Length = 775
Score = 132 bits (320), Expect = 2e-30
Identities = 62/144 (43%), Positives = 86/144 (59%), Gaps = 2/144 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLA-RYVLDDQYTSSGGTKFPIKWAPPE 59
M +L N++HRDLAARN LV + V KVADFGL+ R LD Y + GG K PI+W PE
Sbjct: 530 MRFLSEMNFVHRDLAARNILVNEHLVCKVADFGLSRRKELDGAYETRGG-KIPIRWTAPE 588
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ + +F+S SDVW+ GV+MWE+ + G+ PY N +V+ V++G L P C I+
Sbjct: 589 AIGYKKFTSASDVWSLGVVMWEIMSYGERPYWNWPNQDVIKAVEKGYRLPPPMECPEAIH 648
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
+M CW RP+F + L
Sbjct: 649 QLMLDCWQRDRNHRPTFTTIVSTL 672
>UniRef50_Q8INU0 Cluster: CG14396-PD, isoform D; n=10; Sophophora|Rep:
CG14396-PD, isoform D - Drosophila melanogaster (Fruit
fly)
Length = 1237
Score = 132 bits (320), Expect = 2e-30
Identities = 59/143 (41%), Positives = 84/143 (58%), Gaps = 1/143 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
MAYL +HRDLAARN L+ D + K++DFGL R V DD Y + P+KW PE
Sbjct: 901 MAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYEDDAYLKRSRDRVPVKWMAPE 960
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++SKSDVW+FGVL WE+ T G PY + + ++ G +++P+ C +Y
Sbjct: 961 SLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQNLWSLLKTGYRMDRPENCSEAVY 1020
Query: 120 NVMRACWGHTPEERPSFRVLKEQ 142
+++R CW P RPSF+ L +
Sbjct: 1021 SIVRTCWADEPNGRPSFKFLASE 1043
>UniRef50_A7RHT9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 295
Score = 132 bits (320), Expect = 2e-30
Identities = 62/138 (44%), Positives = 93/138 (67%), Gaps = 2/138 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV-LDDQYT-SSGGTKFPIKWAPP 58
MA+L +HRDLAARN L+ +++V KV+DFG AR + ++D YT + G +FPIKW
Sbjct: 140 MAHLASMKVVHRDLAARNILIDEKSVCKVSDFGFARDIYVEDHYTRKTQGGRFPIKWMAI 199
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E L ++KSDVW++GVL+WE+ T G PY + + EV++ +Q G ++KPK C++E+
Sbjct: 200 ESLLDGVSTTKSDVWSYGVLLWEIVTLGASPYPGMNSQEVINFLQDGYRMDKPKHCLDEL 259
Query: 119 YNVMRACWGHTPEERPSF 136
Y VM CW + + RP+F
Sbjct: 260 YAVMLDCWQLSAQRRPTF 277
>UniRef50_UPI00015B5959 Cluster: PREDICTED: similar to insulin
receptor; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to insulin receptor - Nasonia vitripennis
Length = 1714
Score = 132 bits (319), Expect = 3e-30
Identities = 62/145 (42%), Positives = 90/145 (62%), Gaps = 3/145 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLDDQYTSSGGTK--FPIKWAPP 58
MAYL ++HRDLAARNC+V D+ VK+ DFG+ R V + Y G TK P++W P
Sbjct: 1253 MAYLAAKKFVHRDLAARNCMVSDDLTVKIGDFGMTRDVYETDYYRKG-TKGLLPVRWMAP 1311
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEI 118
E L F+S SDVW++GV++WE+ T PY L+N +V+ V G V+E+P+ C + +
Sbjct: 1312 ESLKDGVFTSFSDVWSYGVVLWEMVTLASQPYQGLSNDQVLRYVIDGGVMERPENCPDIL 1371
Query: 119 YNVMRACWGHTPEERPSFRVLKEQL 143
Y +MR W H RP+F ++ +L
Sbjct: 1372 YGMMRQTWCHKATRRPTFIDIEREL 1396
>UniRef50_Q4SMF1 Cluster: Chromosome 8 SCAF14552, whole genome
shotgun sequence; n=8; Clupeocephala|Rep: Chromosome 8
SCAF14552, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 714
Score = 132 bits (319), Expect = 3e-30
Identities = 66/148 (44%), Positives = 88/148 (59%), Gaps = 5/148 (3%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV--LDDQ---YTSSGGTKFPIKW 55
M YL N++HRDLAARN LV V KV+DFGL+R + LD YT+S G+K P++W
Sbjct: 466 MRYLAERNFVHRDLAARNVLVNSNLVCKVSDFGLSRLMRGLDHNIPTYTASLGSKIPVRW 525
Query: 56 APPEVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCI 115
PE +FSS SDVW+FGVLMWEV + G+ PY ++N EV+ V L P C
Sbjct: 526 TAPEAFQHRKFSSASDVWSFGVLMWEVMSYGERPYWDMSNQEVMKAVADQYRLPAPHSCP 585
Query: 116 NEIYNVMRACWGHTPEERPSFRVLKEQL 143
++++M CW +RP+F L L
Sbjct: 586 PALHSLMLQCWQADRGDRPAFETLLSSL 613
>UniRef50_Q9BLY1 Cluster: Receptor tyrosine kinase; n=5;
Caenorhabditis|Rep: Receptor tyrosine kinase -
Caenorhabditis elegans
Length = 928
Score = 132 bits (319), Expect = 3e-30
Identities = 59/144 (40%), Positives = 85/144 (59%), Gaps = 1/144 (0%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVL-DDQYTSSGGTKFPIKWAPPE 59
M YL +++HRDLA RNCLVGD +K+ADFGL R D Y + P++W E
Sbjct: 714 MEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMRTSYGSDYYKMLHRSWMPVRWMSKE 773
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+ RFS SDVW+FGV +WE+++ G+ PY +N +V++ V +LE P C IY
Sbjct: 774 AIEQGRFSEASDVWSFGVTLWEIWSFGRQPYEGASNQQVIELVANRHLLECPHNCPTNIY 833
Query: 120 NVMRACWGHTPEERPSFRVLKEQL 143
++M CW E RP+F ++ +L
Sbjct: 834 SLMVECWHENIERRPTFSEIRSRL 857
>UniRef50_Q16UV1 Cluster: Protein kinase protein; n=3;
Culicidae|Rep: Protein kinase protein - Aedes aegypti
(Yellowfever mosquito)
Length = 1081
Score = 132 bits (319), Expect = 3e-30
Identities = 61/147 (41%), Positives = 87/147 (59%), Gaps = 3/147 (2%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYV--LDDQYTSSGGTKFPIKWAPP 58
MAYLE ++HRDLA RN L+ N +K+ DFGL R + +D Y + K P W P
Sbjct: 233 MAYLESKRFLHRDLACRNVLLASGNKIKIGDFGLMRALPQQEDCYVMTEHKKVPFPWCAP 292
Query: 59 EVLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQR-GQVLEKPKGCINE 117
E L + +FS SD W F V +WE+FT G+ P+ L S+++ K+ R G+ L P C +
Sbjct: 293 ESLRYRQFSHASDTWMFAVTLWEMFTFGEDPWVGLNGSQILRKIDREGERLHHPDACPPD 352
Query: 118 IYNVMRACWGHTPEERPSFRVLKEQLA 144
+Y +M CW +P ERP+F +KE L+
Sbjct: 353 VYQLMLQCWDKSPAERPTFAAIKEFLS 379
>UniRef50_A7SFD8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 229
Score = 132 bits (319), Expect = 3e-30
Identities = 59/127 (46%), Positives = 84/127 (66%), Gaps = 2/127 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLAR-YVLDDQYTSSGGTKFPIKWAPPE 59
M YL ++HRDLAARN L+ + + K+ DFG++R ++ D YTS GG + P+KW PE
Sbjct: 96 MQYLHSLGFVHRDLAARNILLDSDMICKIGDFGMSRDLMICDYYTSRGG-RIPVKWTAPE 154
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
+N+ R+SS SDVW++GVL++E+++ G PY L N+EVV+ V RG L P C IY
Sbjct: 155 AINYGRYSSASDVWSYGVLLFEIWSLGDKPYANLDNNEVVEAVSRGYRLPPPDHCPTMIY 214
Query: 120 NVMRACW 126
+M CW
Sbjct: 215 RLMVDCW 221
>UniRef50_A3EXK5 Cluster: Fibroblast growth factor receptor b; n=1;
Nematostella vectensis|Rep: Fibroblast growth factor
receptor b - Nematostella vectensis
Length = 591
Score = 132 bits (319), Expect = 3e-30
Identities = 62/149 (41%), Positives = 94/149 (63%), Gaps = 2/149 (1%)
Query: 1 MAYLERHNYIHRDLAARNCLVGDENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAPPE 59
M YLE IHRDLAARN LV D +V+K+ADFGLAR + D D Y + + P+KW E
Sbjct: 404 MEYLESKKCIHRDLAARNVLVSDNHVIKIADFGLARDIHDIDYYRKTTDGRLPVKWMALE 463
Query: 60 VLNFTRFSSKSDVWAFGVLMWEVFTCGKVPYGRLTNSEVVDKVQRGQVLEKPKGCINEIY 119
L ++++SDVWA+G+LMWE+ T G PY + ++ + ++ G +E+P C +++Y
Sbjct: 464 ALFDRVYTAQSDVWAYGILMWEIVTFGGSPYPGIPLWKLFELLKEGYRMEQPVNCQDDVY 523
Query: 120 NVMRACWGHTPEERPSF-RVLKEQLAVIS 147
+M CW P +RP+F ++KE A ++
Sbjct: 524 ALMLRCWHENPNQRPTFAEIVKEMDAKLT 552
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.321 0.137 0.431
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 176,512,284
Number of Sequences: 1657284
Number of extensions: 6761896
Number of successful extensions: 28928
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 4718
Number of HSP's successfully gapped in prelim test: 4236
Number of HSP's that attempted gapping in prelim test: 17807
Number of HSP's gapped (non-prelim): 9739
length of query: 153
length of database: 575,637,011
effective HSP length: 94
effective length of query: 59
effective length of database: 419,852,315
effective search space: 24771286585
effective search space used: 24771286585
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 68 (31.5 bits)
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