Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000966-TA|BGIBMGA000966-PA|IPR003591|Leucine-rich
repeat, typical subtype, IPR001611|Leucine-rich repeat
(454 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 107 1e-22
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 107 1e-22
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 107 1e-22
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 106 2e-22
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 99 3e-20
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 99 3e-20
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 99 4e-20
BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat con... 96 2e-19
BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat con... 96 2e-19
AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein. 96 2e-19
AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens ... 96 2e-19
AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated ... 96 2e-19
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 93 2e-18
BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein. 93 2e-18
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 93 2e-18
BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein. 93 2e-18
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 93 2e-18
AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein. 93 2e-18
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 93 2e-18
U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein. 92 4e-18
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 92 4e-18
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 92 4e-18
BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein. 90 1e-17
BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for IM... 90 1e-17
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 89 3e-17
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 89 3e-17
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 89 3e-17
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 89 3e-17
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 89 3e-17
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 89 3e-17
AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein pr... 86 2e-16
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 86 3e-16
BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat tra... 85 4e-16
BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat tra... 85 4e-16
BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat tra... 85 4e-16
AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein. 85 4e-16
AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat tra... 85 4e-16
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 84 1e-15
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 83 2e-15
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 83 2e-15
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 83 2e-15
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 83 3e-15
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 83 3e-15
BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein. 81 6e-15
BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and... 81 6e-15
AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat neu... 81 6e-15
AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein pr... 81 6e-15
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 81 1e-14
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 81 1e-14
AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein. 80 2e-14
AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein. 80 2e-14
Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein. 79 2e-14
BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein. 79 2e-14
AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat pro... 79 2e-14
AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein. 79 2e-14
BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat tra... 79 3e-14
BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat tra... 79 3e-14
AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat tra... 79 3e-14
AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein. 79 3e-14
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 79 4e-14
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 79 4e-14
BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein. 79 4e-14
AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein. 79 4e-14
AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat tra... 79 4e-14
AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens ... 79 4e-14
AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat neu... 78 6e-14
AY324322-1|AAQ97217.1| 469|Homo sapiens leucine-rich repeat neu... 78 6e-14
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 77 1e-13
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 77 1e-13
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 77 1e-13
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 77 1e-13
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 77 1e-13
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 77 1e-13
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 77 1e-13
AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich repeat-con... 77 1e-13
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 77 1e-13
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 75 4e-13
BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product p... 75 4e-13
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 75 4e-13
AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein. 75 4e-13
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 75 5e-13
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 75 5e-13
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 75 5e-13
AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled recep... 75 5e-13
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 75 7e-13
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 74 1e-12
AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein. 74 1e-12
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 74 1e-12
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 74 1e-12
AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein. 74 1e-12
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 74 1e-12
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 74 1e-12
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 74 1e-12
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 74 1e-12
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 73 2e-12
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 73 2e-12
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 73 2e-12
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 73 2e-12
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 73 2e-12
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 73 3e-12
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat neu... 73 3e-12
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 73 3e-12
CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein. 72 4e-12
BC111067-1|AAI11068.1| 513|Homo sapiens leucine rich repeat con... 72 4e-12
BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor pr... 72 4e-12
AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein. 72 4e-12
AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like fa... 72 4e-12
AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like fa... 72 4e-12
AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled recep... 72 4e-12
AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein. 72 4e-12
AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein. 72 4e-12
AB178281-1|BAD97811.1| 513|Homo sapiens LRRC24 protein protein. 72 4e-12
M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein... 72 5e-12
CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein. 72 5e-12
CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein. 72 5e-12
BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein. 72 5e-12
BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein. 72 5e-12
AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein. 72 5e-12
AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein. 72 5e-12
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 71 6e-12
AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein. 71 6e-12
AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat ne... 71 6e-12
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 71 8e-12
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 71 8e-12
L01131-1|AAA52301.1| 347|Homo sapiens decorin protein. 71 8e-12
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 71 1e-11
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 71 1e-11
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 71 1e-11
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 71 1e-11
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 71 1e-11
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 71 1e-11
BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat neu... 70 1e-11
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 70 2e-11
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 70 2e-11
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 70 2e-11
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 70 2e-11
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 70 2e-11
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 70 2e-11
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 70 2e-11
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 70 2e-11
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 70 2e-11
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 69 3e-11
CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein. 69 3e-11
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 69 3e-11
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 69 3e-11
AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein. 69 3e-11
AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat pro... 69 3e-11
AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich r... 69 3e-11
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 69 3e-11
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 69 3e-11
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 69 3e-11
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 69 3e-11
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 69 3e-11
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 69 3e-11
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 69 3e-11
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 69 3e-11
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 69 3e-11
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 69 3e-11
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 69 3e-11
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 69 3e-11
BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein. 68 6e-11
AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein. 68 6e-11
AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament as... 68 6e-11
AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1) p... 68 6e-11
AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein. 68 6e-11
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 67 1e-10
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 67 1e-10
BC044233-1|AAH44233.1| 692|Homo sapiens leucine rich repeat con... 67 1e-10
AY358322-1|AAQ88688.1| 692|Homo sapiens ELLP3030 protein. 67 1e-10
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 67 1e-10
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 66 3e-10
BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein. 66 3e-10
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 66 3e-10
AL122074-1|CAB59249.1| 333|Homo sapiens hypothetical protein pr... 66 3e-10
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 65 4e-10
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 65 4e-10
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 65 6e-10
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 65 6e-10
AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1 (Drosoph... 65 6e-10
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 65 6e-10
U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3 prot... 64 7e-10
DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3 is... 64 7e-10
BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3 pr... 64 7e-10
BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3 pr... 64 7e-10
BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3 pr... 64 7e-10
BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3 pr... 64 7e-10
BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein. 64 7e-10
AY358316-1|AAQ88682.1| 745|Homo sapiens FPLR1885 protein. 64 7e-10
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 64 7e-10
AB040898-1|BAA95989.2| 785|Homo sapiens KIAA1465 protein protein. 64 7e-10
M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein. 64 1e-09
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 64 1e-09
BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and... 63 2e-09
AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens ... 63 2e-09
BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-li... 62 3e-09
BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-li... 62 3e-09
AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3 pr... 62 3e-09
AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolo... 62 3e-09
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 62 5e-09
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 61 7e-09
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 61 7e-09
AY358116-1|AAQ88483.1| 548|Homo sapiens LGI3 protein. 61 7e-09
AJ487961-1|CAD32308.1| 548|Homo sapiens LGI1-like protein 4 pro... 61 7e-09
AJ487518-1|CAD31786.1| 548|Homo sapiens leucine-rich glioma ina... 61 7e-09
AF467956-1|AAM49554.1| 548|Homo sapiens LGI3 protein. 61 7e-09
BC087848-1|AAH87848.1| 261|Homo sapiens LGI4 protein protein. 61 9e-09
AY358121-1|AAQ88488.1| 261|Homo sapiens LGI4 protein. 61 9e-09
AJ487959-1|CAD32306.1| 537|Homo sapiens LGI1-like protein 3 pro... 61 9e-09
AJ487519-1|CAD31787.1| 537|Homo sapiens leucine-rich glioma ina... 61 9e-09
AF467954-1|AAM49552.1| 537|Homo sapiens LGI4 protein. 61 9e-09
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 60 1e-08
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 60 1e-08
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 60 1e-08
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 60 1e-08
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 60 1e-08
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 60 1e-08
AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens ... 60 1e-08
AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein. 60 2e-08
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 60 2e-08
AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein. 60 2e-08
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 59 4e-08
AL137848-6|CAI16698.1| 243|Homo sapiens asporin (LRR class 1) p... 59 4e-08
AK027359-1|BAB55060.1| 246|Homo sapiens protein ( Homo sapiens ... 59 4e-08
AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich repeat-con... 59 4e-08
BC040879-1|AAH40879.1| 493|Homo sapiens adhesion molecule with ... 58 5e-08
AY237007-1|AAO48948.1| 493|Homo sapiens transmembrane protein A... 58 5e-08
AL355145-6|CAI22942.1| 493|Homo sapiens adhesion molecule with ... 58 5e-08
DQ355157-1|ABC79623.1| 334|Homo sapiens cytokeratin associated ... 58 6e-08
BC114551-1|AAI14552.1| 334|Homo sapiens ISLR2 protein protein. 58 6e-08
BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and... 58 6e-08
AL929554-11|CAH72880.1| 334|Homo sapiens leucine rich repeat co... 58 6e-08
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 58 6e-08
AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens ... 58 6e-08
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 58 6e-08
AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1 (Drosoph... 58 8e-08
AK001991-1|BAA92025.1| 273|Homo sapiens protein ( Homo sapiens ... 58 8e-08
Z29083-1|CAA82324.1| 420|Homo sapiens 5T4 oncofoetal antigen pr... 57 1e-07
BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like fami... 57 1e-07
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 57 1e-07
BC037161-1|AAH37161.1| 420|Homo sapiens trophoblast glycoprotei... 57 1e-07
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 57 1e-07
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 57 1e-07
AL121977-2|CAI21546.1| 420|Homo sapiens trophoblast glycoprotei... 57 1e-07
AJ012159-1|CAA09930.1| 420|Homo sapiens 5T4 oncofetal trophobla... 57 1e-07
AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein. 57 1e-07
BC101761-1|AAI01762.1| 545|Homo sapiens leucine-rich repeat LGI... 57 1e-07
BC101759-1|AAI01760.1| 545|Homo sapiens leucine-rich repeat LGI... 57 1e-07
AJ487958-1|CAD32305.1| 545|Homo sapiens LGI1-like protein 2 pro... 57 1e-07
AJ487516-1|CAD31784.1| 545|Homo sapiens leucine-rich glioma ina... 57 1e-07
AF467955-1|AAM49553.1| 545|Homo sapiens LGI2 protein. 57 1e-07
AB067503-1|BAB67809.1| 542|Homo sapiens KIAA1916 protein protein. 57 1e-07
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 56 2e-07
X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein. 56 2e-07
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 56 2e-07
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 56 2e-07
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 56 2e-07
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 56 2e-07
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 56 2e-07
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 56 2e-07
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 56 3e-07
AK000136-1|BAA90967.1| 187|Homo sapiens protein ( Homo sapiens ... 56 3e-07
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 56 3e-07
S59900-1|AAB26480.1| 695|Homo sapiens follicle stimulating horm... 56 3e-07
M95489-1|AAA52478.1| 695|Homo sapiens follicle stimulating horm... 56 3e-07
D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein. 56 3e-07
BC118548-1|AAI18549.1| 695|Homo sapiens follicle stimulating ho... 56 3e-07
BC096831-1|AAH96831.1| 695|Homo sapiens follicle stimulating ho... 56 3e-07
BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein. 56 3e-07
BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein. 56 3e-07
BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat con... 56 3e-07
AY429104-1|AAR07899.1| 695|Homo sapiens follicle stimulating ho... 56 3e-07
AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein. 56 3e-07
AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leuci... 56 3e-07
AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens ... 55 6e-07
Z94160-2|CAI22122.1| 820|Homo sapiens protein ( Human DNA seque... 54 8e-07
U93091-1|AAC80227.1| 839|Homo sapiens Toll protein homolog prot... 54 8e-07
U88880-1|AAC34135.1| 799|Homo sapiens Toll-like receptor 4 prot... 54 8e-07
BC117422-1|AAI17423.1| 839|Homo sapiens toll-like receptor 4 pr... 54 8e-07
BC019687-1|AAH19687.1| 430|Homo sapiens LRRC4B protein protein. 54 8e-07
AL160272-2|CAH72619.1| 799|Homo sapiens toll-like receptor 4 pr... 54 8e-07
AL160272-1|CAH72618.1| 839|Homo sapiens toll-like receptor 4 pr... 54 8e-07
AF177765-1|AAF05316.1| 839|Homo sapiens toll-like receptor 4 pr... 54 8e-07
AF172171-1|AAF89753.1| 839|Homo sapiens toll-like receptor 4 pr... 54 8e-07
AB067491-1|BAB67797.1| 821|Homo sapiens KIAA1904 protein protein. 54 8e-07
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 54 1e-06
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 54 1e-06
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 54 1e-06
AB031547-1|BAA95681.1| 623|Homo sapiens retina specific protein... 54 1e-06
X75546-1|CAA53233.1| 376|Homo sapiens fibromodulin protein. 54 1e-06
U88878-1|AAC34133.1| 784|Homo sapiens Toll-like receptor 2 prot... 53 2e-06
BC048421-1|AAH48421.1| 453|Homo sapiens LOC150356 protein protein. 53 2e-06
BC033756-1|AAH33756.1| 784|Homo sapiens TLR2 protein protein. 53 2e-06
BC020870-1|AAH20870.1| 649|Homo sapiens fibronectin leucine ric... 53 2e-06
AY358319-1|AAQ88685.1| 649|Homo sapiens FLRT3 protein. 53 2e-06
AL132826-1|CAB86687.1| 649|Homo sapiens fibronectin leucine ric... 53 2e-06
AK074909-1|BAC11284.1| 649|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AK074883-1|BAC11265.1| 627|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AK027694-1|BAB55303.1| 623|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AK027297-1|BAB55023.1| 649|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AF169677-1|AAF28461.1| 649|Homo sapiens leucine-rich repeat tra... 53 2e-06
AF051152-1|AAC34377.1| 784|Homo sapiens Toll/interleukin-1 rece... 53 2e-06
AB040902-1|BAA95993.1| 662|Homo sapiens KIAA1469 protein protein. 53 2e-06
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 53 2e-06
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 53 2e-06
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 53 2e-06
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 53 2e-06
BC022500-1|AAH22500.1| 557|Homo sapiens leucine-rich, glioma in... 53 2e-06
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 53 2e-06
AY358885-1|AAQ89244.1| 557|Homo sapiens LGI1 protein. 53 2e-06
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 53 2e-06
AL358154-2|CAI14982.1| 557|Homo sapiens leucine-rich, glioma in... 53 2e-06
AL358154-1|CAI14981.1| 291|Homo sapiens leucine-rich, glioma in... 53 2e-06
AL157396-3|CAH73838.1| 557|Homo sapiens leucine-rich, glioma in... 53 2e-06
AL157396-2|CAH73837.1| 291|Homo sapiens leucine-rich, glioma in... 53 2e-06
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AF473548-1|AAM22074.1| 291|Homo sapiens leucine-rich glioma ina... 53 2e-06
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 53 2e-06
AF055636-1|AAC99316.1| 557|Homo sapiens leucine-rich glioma-ina... 53 2e-06
X68044-1|CAA48179.1| 280|Homo sapiens follicle stimulating horm... 52 3e-06
BC128608-1|AAI28609.1| 441|Homo sapiens reticulon 4 receptor-li... 52 4e-06
BC125270-1|AAI25271.1| 669|Homo sapiens FSHR protein protein. 52 4e-06
AY250219-1|AAP82836.1| 441|Homo sapiens nogo receptor-like 2 pr... 52 4e-06
AF532859-1|AAP21836.1| 441|Homo sapiens Nogo-66 receptor homolo... 52 4e-06
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 51 7e-06
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 51 1e-05
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 51 1e-05
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 51 1e-05
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 51 1e-05
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 51 1e-05
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 51 1e-05
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 51 1e-05
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 51 1e-05
BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein pr... 50 2e-05
BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix pr... 50 2e-05
AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix pr... 50 2e-05
AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix pr... 50 2e-05
AF502291-1|AAM23001.1| 586|Homo sapiens toll-like receptor 2 pr... 50 2e-05
AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix pr... 50 2e-05
BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein. 50 2e-05
AK027100-1|BAB15657.1| 363|Homo sapiens protein ( Homo sapiens ... 50 2e-05
BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein. 49 3e-05
AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5 pr... 49 3e-05
AF051151-1|AAC34376.1| 858|Homo sapiens Toll/interleukin-1 rece... 49 3e-05
AB060695-1|BAB43955.1| 858|Homo sapiens Toll-like receptor 5 pr... 49 3e-05
AB032989-1|BAA86477.1| 437|Homo sapiens KIAA1163 protein protein. 49 3e-05
BC111013-1|AAI11014.1| 428|Homo sapiens immunoglobulin superfam... 49 4e-05
BC022478-1|AAH22478.1| 428|Homo sapiens immunoglobulin superfam... 49 4e-05
AY358871-1|AAQ89230.1| 428|Homo sapiens ISLR protein. 49 4e-05
AK223267-1|BAD96987.1| 428|Homo sapiens immunoglobulin superfam... 49 4e-05
AB024537-1|BAA85971.1| 428|Homo sapiens ISLR protein. 49 4e-05
AB024536-1|BAA85970.1| 428|Homo sapiens ISLR protein. 49 4e-05
AB003184-1|BAA22848.1| 428|Homo sapiens ISLR protein. 49 4e-05
BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein. 48 5e-05
BC035645-1|AAH35645.1| 1266|Homo sapiens Similar to RIKEN cDNA 3... 48 5e-05
AY358306-1|AAQ88673.1| 616|Homo sapiens GPR125 protein. 48 5e-05
S57793-1|AAB19917.2| 699|Homo sapiens luteinizing hormone recep... 48 7e-05
AL591063-1|CAI15264.1| 789|Homo sapiens RP11-535K1.2 protein. 48 7e-05
AB033072-1|BAA86560.1| 832|Homo sapiens KIAA1246 protein protein. 48 7e-05
M73746-1|AAA70231.1| 685|Homo sapiens lutropin/choriogonadotrop... 48 9e-05
BC110418-1|AAI10419.1| 504|Homo sapiens adhesion molecule with ... 48 9e-05
BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein. 48 9e-05
BC101365-1|AAI01366.1| 504|Homo sapiens adhesion molecule with ... 48 9e-05
BC101364-1|AAI01365.1| 504|Homo sapiens adhesion molecule with ... 48 9e-05
BC101363-1|AAI01364.1| 504|Homo sapiens adhesion molecule with ... 48 9e-05
BC095477-1|AAH95477.1| 522|Homo sapiens AMIGO2 protein protein. 48 9e-05
BC047595-1|AAH47595.1| 522|Homo sapiens adhesion molecule with ... 48 9e-05
AY454159-1|AAR83271.1| 522|Homo sapiens DEGA/AMIGO-2 precursor ... 48 9e-05
AY358134-1|AAQ88501.1| 504|Homo sapiens TWLV6084 protein. 48 9e-05
AY237005-1|AAO48946.1| 522|Homo sapiens transmembrane protein A... 48 9e-05
AY237003-1|AAO48944.1| 504|Homo sapiens transmembrane protein A... 48 9e-05
AB080610-1|BAC81189.1| 522|Homo sapiens alivin 1 protein. 48 9e-05
AB058754-1|BAB47480.1| 523|Homo sapiens KIAA1851 protein protein. 48 9e-05
BC071866-1|AAH71866.1| 460|Homo sapiens Unknown (protein for IM... 47 1e-04
BC015581-1|AAH15581.2| 635|Homo sapiens leucine rich repeat and... 47 1e-04
BC007718-1|AAH07718.1| 541|Homo sapiens LRFN4 protein protein. 47 1e-04
AB209005-1|BAD92242.1| 622|Homo sapiens leucine rich repeat and... 47 1e-04
BC032713-1|AAH32713.1| 1032|Homo sapiens toll-like receptor 9 pr... 47 2e-04
AY359085-1|AAQ89443.1| 1032|Homo sapiens TLR9 protein. 47 2e-04
AF259262-1|AAF72189.1| 1032|Homo sapiens toll-like receptor 9 fo... 47 2e-04
AF246973-1|AAG01735.1| 216|Homo sapiens toll-like receptor 9 pr... 47 2e-04
AF246972-1|AAG01734.1| 333|Homo sapiens toll-like receptor 9 pr... 47 2e-04
AF245704-1|AAF78037.1| 1032|Homo sapiens toll-like receptor 9 pr... 47 2e-04
AB045180-1|BAB19259.1| 1032|Homo sapiens toll-like receptor 9 pr... 47 2e-04
AY899848-1|AAX85196.1| 189|Homo sapiens LGR7.1 protein. 46 2e-04
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 46 4e-04
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 46 4e-04
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 46 4e-04
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 46 4e-04
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 46 4e-04
X84753-1|CAA59234.1| 701|Homo sapiens luteinising hormone-chori... 45 5e-04
M63108-1|AAA59515.1| 699|Homo sapiens luteinizing hormone-chori... 45 5e-04
BC016048-1|AAH16048.1| 317|Homo sapiens LRRC38 protein protein. 45 5e-04
AL603749-2|CAH70436.1| 294|Homo sapiens leucine rich repeat con... 45 5e-04
AL354712-1|CAI21926.1| 294|Homo sapiens leucine rich repeat con... 45 5e-04
DQ864979-1|ABI23432.1| 193|Homo sapiens RTN4RL2 protein. 45 6e-04
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 45 6e-04
AY090637-1|AAM09084.1| 320|Homo sapiens tumor endothelial marke... 45 6e-04
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 45 6e-04
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 45 6e-04
BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine ric... 44 8e-04
BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine ric... 44 8e-04
AY358287-1|AAQ88654.1| 660|Homo sapiens FLRT2 protein. 44 8e-04
AF169676-1|AAF28460.1| 660|Homo sapiens leucine-rich repeat tra... 44 8e-04
AB007865-1|BAA23701.2| 706|Homo sapiens KIAA0405 protein. 44 8e-04
M65085-1|AAA52477.1| 695|Homo sapiens follicle stimulating horm... 44 0.001
AK027296-1|BAB55022.1| 185|Homo sapiens protein ( Homo sapiens ... 44 0.001
AC087816-1|AAX88979.1| 226|Homo sapiens unknown protein. 44 0.001
AY358298-1|AAQ88665.1| 598|Homo sapiens CSRV314 protein. 43 0.002
AF259263-1|AAF72190.1| 975|Homo sapiens toll-like receptor 9 fo... 43 0.002
M73747-1|AAA70232.1| 763|Homo sapiens thyroid stimulating hormo... 43 0.003
BC074741-1|AAH74741.1| 345|Homo sapiens leucine-rich repeats an... 43 0.003
BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein. 43 0.003
AF225421-1|AAG09723.1| 345|Homo sapiens HT017 protein. 43 0.003
AF138301-1|AAF61437.1| 250|Homo sapiens decorin B protein. 43 0.003
AK074099-1|BAB84925.1| 1310|Homo sapiens FLJ00170 protein protein. 42 0.003
AF177766-1|AAF07823.1| 752|Homo sapiens human toll-like recepto... 42 0.003
AC096718-1|AAY41008.1| 132|Homo sapiens unknown protein. 42 0.003
U21128-1|AAA91639.1| 338|Homo sapiens lumican protein. 42 0.004
U18728-1|AAA85268.1| 338|Homo sapiens lumican protein. 42 0.004
BT006707-1|AAP35353.1| 338|Homo sapiens lumican protein. 42 0.004
BC132983-1|AAI32984.1| 313|Homo sapiens leucine rich repeat con... 42 0.004
BC132981-1|AAI32982.1| 313|Homo sapiens leucine rich repeat con... 42 0.004
BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein. 42 0.004
BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat con... 42 0.004
BC035997-1|AAH35997.1| 338|Homo sapiens lumican protein. 42 0.004
BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein. 42 0.004
BC007038-1|AAH07038.1| 338|Homo sapiens lumican protein. 42 0.004
AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein pr... 42 0.004
AL157714-2|CAI15338.1| 313|Homo sapiens novel protein protein. 42 0.004
AK223177-1|BAD96897.1| 338|Homo sapiens lumican variant protein. 42 0.004
AK098677-1|BAC05375.1| 313|Homo sapiens protein ( Homo sapiens ... 42 0.004
AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens ... 42 0.004
BC040732-1|AAH40732.1| 269|Homo sapiens LRTM1 protein protein. 42 0.006
M32215-1|AAA61236.1| 764|Homo sapiens thyroid stimulatory hormo... 41 0.008
M31774-1|AAA36783.1| 764|Homo sapiens protein ( Human thyrotrop... 41 0.008
M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane glycopr... 41 0.008
J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein. 41 0.008
BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib (platel... 41 0.008
AY429111-1|AAR07906.1| 764|Homo sapiens thyroid stimulating hor... 41 0.008
AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein I... 41 0.008
AK027500-1|BAB55157.1| 315|Homo sapiens protein ( Homo sapiens ... 41 0.008
AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib (platel... 41 0.008
AB209207-1|BAD92444.1| 770|Homo sapiens thyroid stimulating hor... 41 0.008
AB086948-1|BAC10305.1| 626|Homo sapiens platelet glycoprotein I... 41 0.008
AB038516-1|BAB12038.1| 626|Homo sapiens platelet glycoprotein I... 41 0.010
U32907-1|AAB41565.1| 313|Homo sapiens p37NB protein. 40 0.014
S49816-1|AAB24246.1| 253|Homo sapiens thyrotropin receptor-I pr... 40 0.014
S45272-1|AAB23390.2| 253|Homo sapiens thyrotropin receptor prot... 40 0.014
BC141970-1|AAI41971.1| 253|Homo sapiens thyroid stimulating hor... 40 0.014
BC127628-1|AAI27629.1| 274|Homo sapiens TSHR protein protein. 40 0.014
BC126156-1|AAI26157.1| 370|Homo sapiens leucine rich repeat con... 40 0.014
BC120973-1|AAI20974.1| 253|Homo sapiens thyroid stimulating hor... 40 0.014
BC120972-1|AAI20973.1| 231|Homo sapiens TSHR protein protein. 40 0.014
BC108653-1|AAI08654.1| 253|Homo sapiens thyroid stimulating hor... 40 0.014
BC063613-1|AAH63613.1| 253|Homo sapiens thyroid stimulating hor... 40 0.014
BC027903-1|AAH27903.1| 441|Homo sapiens leucine rich repeat con... 40 0.014
BC024205-1|AAH24205.1| 253|Homo sapiens thyroid stimulating hor... 40 0.014
BC009237-1|AAH09237.1| 253|Homo sapiens thyroid stimulating hor... 40 0.014
AY358889-1|AAQ89248.1| 440|Homo sapiens p37NB protein. 40 0.014
AK222987-1|BAD96707.1| 370|Homo sapiens leucine rich repeat con... 40 0.014
AK024955-1|BAB15042.1| 370|Homo sapiens protein ( Homo sapiens ... 40 0.014
AC073127-2|AAS07483.1| 313|Homo sapiens unknown protein. 40 0.014
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 40 0.018
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 40 0.018
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 40 0.018
BC032667-1|AAH32667.1| 352|Homo sapiens keratocan protein. 40 0.018
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 40 0.018
BC030958-1|AAH30958.1| 322|Homo sapiens epiphycan protein. 40 0.018
BC019839-1|AAH19839.1| 297|Homo sapiens LOC150356 protein protein. 40 0.018
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 40 0.018
AF205403-1|AAF69126.1| 352|Homo sapiens keratocan protein. 40 0.018
AF065988-1|AAC17741.1| 352|Homo sapiens keratocan protein. 40 0.018
AF063301-1|AAC16390.1| 352|Homo sapiens keratan sulfate proteog... 40 0.018
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 40 0.018
U59111-1|AAC50945.1| 322|Homo sapiens dermatan sulfate proteogl... 39 0.032
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 39 0.032
BC119649-1|AAI19650.1| 257|Homo sapiens leucine rich repeat con... 39 0.032
BC119648-1|AAI19649.1| 257|Homo sapiens leucine rich repeat con... 39 0.032
AY358120-1|AAQ88487.1| 257|Homo sapiens LLR protein protein. 39 0.032
AY061857-1|AAL35741.1| 257|Homo sapiens leucine-rich repeat dom... 39 0.032
AB058646-1|BAB40229.1| 257|Homo sapiens LRRC3 protein. 39 0.032
BT007440-1|AAP36108.1| 353|Homo sapiens hypothetical protein, e... 39 0.042
BC027720-1|AAH27720.1| 740|Homo sapiens chromosome 20 open read... 39 0.042
BC020975-1|AAH20975.1| 353|Homo sapiens tsukushin protein. 39 0.042
AY358317-1|AAQ88683.1| 353|Homo sapiens E2IG4 protein. 39 0.042
AF191019-1|AAF09483.1| 353|Homo sapiens E2IG4 protein. 39 0.042
AF138302-1|AAD44714.1| 212|Homo sapiens decorin variant C protein. 39 0.042
BC109112-1|AAI09113.1| 811|Homo sapiens TLR10 protein protein. 38 0.073
BC109111-1|AAI09112.1| 811|Homo sapiens TLR10 protein protein. 38 0.073
BC089406-1|AAH89406.1| 811|Homo sapiens TLR10 protein protein. 38 0.073
BC087849-1|AAH87849.1| 259|Homo sapiens LRRC3B protein protein. 38 0.073
BC067784-1|AAH67784.1| 259|Homo sapiens leucine rich repeat con... 38 0.073
BC050097-1|AAH50097.1| 383|Homo sapiens LRRC27 protein protein. 38 0.073
BC040656-1|AAH40656.1| 259|Homo sapiens LRRC3B protein protein. 38 0.073
AY358300-1|AAQ88667.1| 811|Homo sapiens TLR10 protein. 38 0.073
AY358282-1|AAQ88649.1| 259|Homo sapiens NLVD195 protein. 38 0.073
AL590105-6|CAI13017.1| 530|Homo sapiens novel protein protein. 38 0.073
AL590105-5|CAI13016.1| 383|Homo sapiens novel protein protein. 38 0.073
AK127604-1|BAC87053.1| 137|Homo sapiens protein ( Homo sapiens ... 38 0.073
>M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth factor
binding protein complex protein.
Length = 605
Score = 107 bits (256), Expect = 1e-22
Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 2/237 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL+ + +L LSR LR ++++ F L +L++L LD + + P AF GL LR L +
Sbjct: 215 SGLA-ELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDL 273
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
H +A + F L + + L+HN IA + F +F+ + L +N I+++ +
Sbjct: 274 SHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERS 333
Query: 234 FSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
F GL + + L + ++ ++ AF GL + V+ L+ L +L F GL ++ L L
Sbjct: 334 FEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHL 393
Query: 293 RESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
S LG I+ +F GL + L + +N + GIEE SL + LT N + P
Sbjct: 394 EGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLP 450
Score = 97.5 bits (232), Expect = 9e-20
Identities = 67/244 (27%), Positives = 114/244 (46%), Gaps = 1/244 (0%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L L R LR L FAH L L L L+R+ F GL L +L + L
Sbjct: 123 NLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSL 182
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
A + AF L ++ +VL NR+A ++ F+G + + L N ++ I + F L
Sbjct: 183 AVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP 242
Query: 239 DVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
+ ++ L I + P AF GL+ + L+L+ + LL DTF GL+ + L L + +
Sbjct: 243 RLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAI 302
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVE 357
++ +F L ++ L++ +N+I + E S + V L N + E L +
Sbjct: 303 ASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLT 362
Query: 358 NIII 361
N+ +
Sbjct: 363 NVAV 366
Score = 88.2 bits (209), Expect = 5e-17
Identities = 63/217 (29%), Positives = 100/217 (46%), Gaps = 2/217 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G+ GL S+ L+L L VL AF L LR L L L ++P F GL LRE
Sbjct: 164 GLFEGLG-SLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRE 222
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L + L + + F L + + L N IA + AF G + + L +N + +L
Sbjct: 223 LDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLL 282
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GL + + L + I ++ P+ F L + L+L + L +F GL ++
Sbjct: 283 EDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEV 342
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
L+L + L +K G+F GL +V + + N + + E
Sbjct: 343 LTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPE 379
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/243 (25%), Positives = 119/243 (48%), Gaps = 1/243 (0%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+S L +P G+ L L +L + AF +L L L L L + P A
Sbjct: 58 VFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQA 117
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
GL L L+++ L ++ FA + S+ L++NR++++E F G + ++L
Sbjct: 118 LLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNL 177
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
N + + AF GL + ++ L + ++P F+GL + L+L+ L ++ +
Sbjct: 178 GWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANV 237
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L R+ +L L + + + G+F GL+ + L++ +N++ G+ E + +RV +L
Sbjct: 238 FVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRL 297
Query: 341 TGN 343
+ N
Sbjct: 298 SHN 300
Score = 74.5 bits (175), Expect = 7e-13
Identities = 53/200 (26%), Positives = 90/200 (45%), Gaps = 1/200 (0%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L LS + L D F L LR L L + +RP F+ L L EL + H + +
Sbjct: 271 LDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLA 330
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
+F L + + L HN++ ++++ AF G + +++L N ++ + F GL +
Sbjct: 331 ERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHS 390
Query: 243 IELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIK 301
+ L S + I P F GL G+ L L L + + GL + L L + L +
Sbjct: 391 LHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLP 450
Query: 302 VGSFDGLQHVDTLEICNNKI 321
F GL ++ L + N++
Sbjct: 451 HRLFQGLGKLEYLLLSRNRL 470
Score = 51.2 bits (117), Expect = 7e-06
Identities = 33/119 (27%), Positives = 53/119 (44%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
+V ++LS LR L F L +L L L+ L RIRP F GL LR L+++ L
Sbjct: 363 NVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGL 422
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
++ + L + + LT N++ + F G + + L N + + A L
Sbjct: 423 VGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPL 481
Score = 42.7 bits (96), Expect = 0.003
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 1/114 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
+GLS + +L L L + + L +L L L + LT + F+GL +L L +
Sbjct: 407 TGLS-GLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLL 465
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIK 227
LA + + A LQ + ++HNR+ + + A + +SLRNN ++
Sbjct: 466 SRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
Score = 42.3 bits (95), Expect = 0.003
Identities = 30/123 (24%), Positives = 55/123 (44%), Gaps = 3/123 (2%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+ + ++ P AF L +G L L L SL P GL + L L + L + +G+F
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV---VLEVENIIIRG 363
+ +L + NN++ +E+ S+ L N + P+A + + +++ G
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 364 NHL 366
N L
Sbjct: 204 NRL 206
>AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like
growth factor binding protein, acid labile subunit)
protein.
Length = 605
Score = 107 bits (256), Expect = 1e-22
Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 2/237 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL+ + +L LSR LR ++++ F L +L++L LD + + P AF GL LR L +
Sbjct: 215 SGLA-ELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDL 273
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
H +A + F L + + L+HN IA + F +F+ + L +N I+++ +
Sbjct: 274 SHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERS 333
Query: 234 FSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
F GL + + L + ++ ++ AF GL + V+ L+ L +L F GL ++ L L
Sbjct: 334 FEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHL 393
Query: 293 RESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
S LG I+ +F GL + L + +N + GIEE SL + LT N + P
Sbjct: 394 EGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLP 450
Score = 97.5 bits (232), Expect = 9e-20
Identities = 67/244 (27%), Positives = 114/244 (46%), Gaps = 1/244 (0%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L L R LR L FAH L L L L+R+ F GL L +L + L
Sbjct: 123 NLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSL 182
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
A + AF L ++ +VL NR+A ++ F+G + + L N ++ I + F L
Sbjct: 183 AVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP 242
Query: 239 DVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
+ ++ L I + P AF GL+ + L+L+ + LL DTF GL+ + L L + +
Sbjct: 243 RLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAI 302
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVE 357
++ +F L ++ L++ +N+I + E S + V L N + E L +
Sbjct: 303 ASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLT 362
Query: 358 NIII 361
N+ +
Sbjct: 363 NVAV 366
Score = 88.2 bits (209), Expect = 5e-17
Identities = 63/217 (29%), Positives = 100/217 (46%), Gaps = 2/217 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G+ GL S+ L+L L VL AF L LR L L L ++P F GL LRE
Sbjct: 164 GLFEGLG-SLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRE 222
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L + L + + F L + + L N IA + AF G + + L +N + +L
Sbjct: 223 LDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLL 282
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GL + + L + I ++ P+ F L + L+L + L +F GL ++
Sbjct: 283 EDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEV 342
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
L+L + L +K G+F GL +V + + N + + E
Sbjct: 343 LTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPE 379
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/243 (25%), Positives = 119/243 (48%), Gaps = 1/243 (0%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+S L +P G+ L L +L + AF +L L L L L + P A
Sbjct: 58 VFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQA 117
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
GL L L+++ L ++ FA + S+ L++NR++++E F G + ++L
Sbjct: 118 LLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNL 177
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
N + + AF GL + ++ L + ++P F+GL + L+L+ L ++ +
Sbjct: 178 GWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANV 237
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L R+ +L L + + + G+F GL+ + L++ +N++ G+ E + +RV +L
Sbjct: 238 FVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRL 297
Query: 341 TGN 343
+ N
Sbjct: 298 SHN 300
Score = 74.5 bits (175), Expect = 7e-13
Identities = 53/200 (26%), Positives = 90/200 (45%), Gaps = 1/200 (0%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L LS + L D F L LR L L + +RP F+ L L EL + H + +
Sbjct: 271 LDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLA 330
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
+F L + + L HN++ ++++ AF G + +++L N ++ + F GL +
Sbjct: 331 ERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHS 390
Query: 243 IELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIK 301
+ L S + I P F GL G+ L L L + + GL + L L + L +
Sbjct: 391 LHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLP 450
Query: 302 VGSFDGLQHVDTLEICNNKI 321
F GL ++ L + N++
Sbjct: 451 HRLFQGLGKLEYLLLSRNRL 470
Score = 51.2 bits (117), Expect = 7e-06
Identities = 33/119 (27%), Positives = 53/119 (44%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
+V ++LS LR L F L +L L L+ L RIRP F GL LR L+++ L
Sbjct: 363 NVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGL 422
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
++ + L + + LT N++ + F G + + L N + + A L
Sbjct: 423 VGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPL 481
Score = 42.7 bits (96), Expect = 0.003
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 1/114 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
+GLS + +L L L + + L +L L L + LT + F+GL +L L +
Sbjct: 407 TGLS-GLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLL 465
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIK 227
LA + + A LQ + ++HNR+ + + A + +SLRNN ++
Sbjct: 466 SRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
Score = 42.3 bits (95), Expect = 0.003
Identities = 30/123 (24%), Positives = 55/123 (44%), Gaps = 3/123 (2%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+ + ++ P AF L +G L L L SL P GL + L L + L + +G+F
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV---VLEVENIIIRG 363
+ +L + NN++ +E+ S+ L N + P+A + + +++ G
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 364 NHL 366
N L
Sbjct: 204 NRL 206
>AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit
protein.
Length = 605
Score = 107 bits (256), Expect = 1e-22
Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 2/237 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL+ + +L LSR LR ++++ F L +L++L LD + + P AF GL LR L +
Sbjct: 215 SGLA-ELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDL 273
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
H +A + F L + + L+HN IA + F +F+ + L +N I+++ +
Sbjct: 274 SHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERS 333
Query: 234 FSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
F GL + + L + ++ ++ AF GL + V+ L+ L +L F GL ++ L L
Sbjct: 334 FEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHL 393
Query: 293 RESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
S LG I+ +F GL + L + +N + GIEE SL + LT N + P
Sbjct: 394 EGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLP 450
Score = 97.5 bits (232), Expect = 9e-20
Identities = 67/244 (27%), Positives = 114/244 (46%), Gaps = 1/244 (0%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L L R LR L FAH L L L L+R+ F GL L +L + L
Sbjct: 123 NLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSL 182
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
A + AF L ++ +VL NR+A ++ F+G + + L N ++ I + F L
Sbjct: 183 AVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP 242
Query: 239 DVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
+ ++ L I + P AF GL+ + L+L+ + LL DTF GL+ + L L + +
Sbjct: 243 RLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAI 302
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVE 357
++ +F L ++ L++ +N+I + E S + V L N + E L +
Sbjct: 303 ASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLT 362
Query: 358 NIII 361
N+ +
Sbjct: 363 NVAV 366
Score = 88.2 bits (209), Expect = 5e-17
Identities = 63/217 (29%), Positives = 100/217 (46%), Gaps = 2/217 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G+ GL S+ L+L L VL AF L LR L L L ++P F GL LRE
Sbjct: 164 GLFEGLG-SLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRE 222
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L + L + + F L + + L N IA + AF G + + L +N + +L
Sbjct: 223 LDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLL 282
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GL + + L + I ++ P+ F L + L+L + L +F GL ++
Sbjct: 283 EDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEV 342
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
L+L + L +K G+F GL +V + + N + + E
Sbjct: 343 LTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPE 379
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/243 (25%), Positives = 119/243 (48%), Gaps = 1/243 (0%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+S L +P G+ L L +L + AF +L L L L L + P A
Sbjct: 58 VFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQA 117
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
GL L L+++ L ++ FA + S+ L++NR++++E F G + ++L
Sbjct: 118 LLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNL 177
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
N + + AF GL + ++ L + ++P F+GL + L+L+ L ++ +
Sbjct: 178 GWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANV 237
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L R+ +L L + + + G+F GL+ + L++ +N++ G+ E + +RV +L
Sbjct: 238 FVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRL 297
Query: 341 TGN 343
+ N
Sbjct: 298 SHN 300
Score = 74.5 bits (175), Expect = 7e-13
Identities = 53/200 (26%), Positives = 90/200 (45%), Gaps = 1/200 (0%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L LS + L D F L LR L L + +RP F+ L L EL + H + +
Sbjct: 271 LDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLA 330
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
+F L + + L HN++ ++++ AF G + +++L N ++ + F GL +
Sbjct: 331 ERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHS 390
Query: 243 IELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIK 301
+ L S + I P F GL G+ L L L + + GL + L L + L +
Sbjct: 391 LHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLP 450
Query: 302 VGSFDGLQHVDTLEICNNKI 321
F GL ++ L + N++
Sbjct: 451 HRLFQGLGKLEYLLLSRNRL 470
Score = 51.2 bits (117), Expect = 7e-06
Identities = 33/119 (27%), Positives = 53/119 (44%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
+V ++LS LR L F L +L L L+ L RIRP F GL LR L+++ L
Sbjct: 363 NVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGL 422
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
++ + L + + LT N++ + F G + + L N + + A L
Sbjct: 423 VGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPL 481
Score = 42.7 bits (96), Expect = 0.003
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 1/114 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
+GLS + +L L L + + L +L L L + LT + F+GL +L L +
Sbjct: 407 TGLS-GLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLL 465
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIK 227
LA + + A LQ + ++HNR+ + + A + +SLRNN ++
Sbjct: 466 SRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
Score = 42.3 bits (95), Expect = 0.003
Identities = 30/123 (24%), Positives = 55/123 (44%), Gaps = 3/123 (2%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+ + ++ P AF L +G L L L SL P GL + L L + L + +G+F
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV---VLEVENIIIRG 363
+ +L + NN++ +E+ S+ L N + P+A + + +++ G
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 364 NHL 366
N L
Sbjct: 204 NRL 206
>BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth factor
binding protein, acid labile subunit protein.
Length = 605
Score = 106 bits (254), Expect = 2e-22
Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 2/237 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL+ + +L LSR LR ++++ F L +L++L LD + + P AF GL LR L +
Sbjct: 215 SGLA-ELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDL 273
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
H +A + F L + + L+HN IA + F +F+ + L +N I+++ +
Sbjct: 274 SHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERS 333
Query: 234 FSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
F GL + + L + ++ ++ AF GL + V+ L+ L +L F GL ++ L L
Sbjct: 334 FEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHL 393
Query: 293 RESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
S LG I+ +F GL + L + +N + GIEE SL + LT N + P
Sbjct: 394 EGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLP 450
Score = 96.7 bits (230), Expect = 1e-19
Identities = 67/244 (27%), Positives = 114/244 (46%), Gaps = 1/244 (0%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L L R LR L FAH L L L L+R+ F GL L +L + L
Sbjct: 123 NLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSL 182
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
A + AF L ++ +VL NR+A ++ F+G + + L N ++ I + F L
Sbjct: 183 AVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLP 242
Query: 239 DVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
+ ++ L I + P AF GL+ + L+L+ + LL DTF GL+ + L L + +
Sbjct: 243 RLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAI 302
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVE 357
++ +F L ++ L++ +N+I + E S + V L N + E L +
Sbjct: 303 ASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLT 362
Query: 358 NIII 361
N+ +
Sbjct: 363 NMAV 366
Score = 87.0 bits (206), Expect = 1e-16
Identities = 62/217 (28%), Positives = 100/217 (46%), Gaps = 2/217 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G+ GL S+ L+L L VL AF L LR L L L ++P F GL LRE
Sbjct: 164 GLFEGLG-SLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRE 222
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L + L + + F L + + L N IA + AF G + + L +N + +L
Sbjct: 223 LDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLL 282
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GL + + L + I ++ P+ F L + L+L + L +F GL ++
Sbjct: 283 EDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEV 342
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
L+L + L +K G+F GL ++ + + N + + E
Sbjct: 343 LTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPE 379
Score = 83.4 bits (197), Expect = 1e-15
Identities = 63/243 (25%), Positives = 119/243 (48%), Gaps = 1/243 (0%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+S L +P G+ L L +L + AF +L L L L L + P A
Sbjct: 58 VFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQA 117
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
GL L L+++ L ++ FA + S+ L++NR++++E F G + ++L
Sbjct: 118 LLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNL 177
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
N + + AF GL + ++ L + ++P F+GL + L+L+ L ++ +
Sbjct: 178 GWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANV 237
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L R+ +L L + + + G+F GL+ + L++ +N++ G+ E + +RV +L
Sbjct: 238 FVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRL 297
Query: 341 TGN 343
+ N
Sbjct: 298 SHN 300
Score = 73.7 bits (173), Expect = 1e-12
Identities = 53/200 (26%), Positives = 90/200 (45%), Gaps = 1/200 (0%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L LS + L D F L LR L L + +RP F+ L L EL + H + +
Sbjct: 271 LDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLA 330
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
+F L + + L HN++ ++++ AF G + +++L N ++ + F GL +
Sbjct: 331 ERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHS 390
Query: 243 IELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIK 301
+ L S + I P F GL G+ L L L + + GL + L L + L +
Sbjct: 391 LHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLP 450
Query: 302 VGSFDGLQHVDTLEICNNKI 321
F GL ++ L + N++
Sbjct: 451 HRLFQGLGKLEYLLLSRNRL 470
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/115 (27%), Positives = 51/115 (44%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
++LS LR L F L +L L L+ L RIRP F GL LR L+++ L ++
Sbjct: 367 MNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIE 426
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
+ L + + LT N++ + F G + + L N + + A L
Sbjct: 427 EQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPL 481
Score = 42.7 bits (96), Expect = 0.003
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 1/114 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
+GLS + +L L L + + L +L L L + LT + F+GL +L L +
Sbjct: 407 TGLS-GLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLL 465
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIK 227
LA + + A LQ + ++HNR+ + + A + +SLRNN ++
Sbjct: 466 SRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
Score = 42.3 bits (95), Expect = 0.003
Identities = 30/123 (24%), Positives = 55/123 (44%), Gaps = 3/123 (2%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+ + ++ P AF L +G L L L SL P GL + L L + L + +G+F
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV---VLEVENIIIRG 363
+ +L + NN++ +E+ S+ L N + P+A + + +++ G
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 364 NHL 366
N L
Sbjct: 204 NRL 206
>BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein.
Length = 581
Score = 99.1 bits (236), Expect = 3e-20
Identities = 68/265 (25%), Positives = 122/265 (46%), Gaps = 1/265 (0%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C SQV C A + VP+ L + L + + L F ++ L L ++ L+
Sbjct: 31 CSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRIEKNELS 90
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
RI P AFR L LR L + + L + F L ++ S++L+ N++ QI+ F+ +
Sbjct: 91 RITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSN 150
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLP 274
+ + L N ++ I AF L + ++ L + + I P+ F L + VL L L
Sbjct: 151 LKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLT 210
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
+ TF GL+ + L+L+++ +G++ G F ++ L + NN I + +Q
Sbjct: 211 DIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQ 270
Query: 335 VRVFKLTGNHMLESPEAVVLEVENI 359
+ L GN + E + + N+
Sbjct: 271 LNRLTLFGNSLKELSPGIFGPMPNL 295
Score = 84.2 bits (199), Expect = 9e-16
Identities = 76/317 (23%), Positives = 136/317 (42%), Gaps = 10/317 (3%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSP---SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDAC 152
C + ++ + L +P G +T+L+L + L + F HL L+ L L
Sbjct: 148 CSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYEN 207
Query: 153 NLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAG 212
LT I F GL L+EL +Q + + F N+ + L++N I+Q+ F
Sbjct: 208 RLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQ 267
Query: 213 TNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFM 271
+N ++L N +K + F + ++ ++ L + I ++ F+ L + VL L+
Sbjct: 268 LPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRN 327
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+ + P F+GL + LSL + L + F L ++ + + NN++ +
Sbjct: 328 QISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFAN 387
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVENII-IRGNHLPCECGRD--PFTNPLALSQDFAEE 388
N + +L N + P + + + +R P C D P N L L+Q
Sbjct: 388 VNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGT 447
Query: 389 N---YCISPLKVRGRSL 402
+ C SP VRG+SL
Sbjct: 448 DTVPVCFSPANVRGQSL 464
>BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat
containing 15 protein.
Length = 581
Score = 99.1 bits (236), Expect = 3e-20
Identities = 68/265 (25%), Positives = 122/265 (46%), Gaps = 1/265 (0%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C SQV C A + VP+ L + L + + L F ++ L L ++ L+
Sbjct: 31 CSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRIEKNELS 90
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
RI P AFR L LR L + + L + F L ++ S++L+ N++ QI+ F+ +
Sbjct: 91 RITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSN 150
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLP 274
+ + L N ++ I AF L + ++ L + + I P+ F L + VL L L
Sbjct: 151 LKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLT 210
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
+ TF GL+ + L+L+++ +G++ G F ++ L + NN I + +Q
Sbjct: 211 DIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQ 270
Query: 335 VRVFKLTGNHMLESPEAVVLEVENI 359
+ L GN + E + + N+
Sbjct: 271 LNRLTLFGNSLKELSPGIFGPMPNL 295
Score = 84.2 bits (199), Expect = 9e-16
Identities = 76/317 (23%), Positives = 136/317 (42%), Gaps = 10/317 (3%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSP---SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDAC 152
C + ++ + L +P G +T+L+L + L + F HL L+ L L
Sbjct: 148 CSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYEN 207
Query: 153 NLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAG 212
LT I F GL L+EL +Q + + F N+ + L++N I+Q+ F
Sbjct: 208 RLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQ 267
Query: 213 TNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFM 271
+N ++L N +K + F + ++ ++ L + I ++ F+ L + VL L+
Sbjct: 268 LPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRN 327
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+ + P F+GL + LSL + L + F L ++ + + NN++ +
Sbjct: 328 QISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFAN 387
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVENII-IRGNHLPCECGRD--PFTNPLALSQDFAEE 388
N + +L N + P + + + +R P C D P N L L+Q
Sbjct: 388 VNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGT 447
Query: 389 N---YCISPLKVRGRSL 402
+ C SP VRG+SL
Sbjct: 448 DTVPVCFSPANVRGQSL 464
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 98.7 bits (235), Expect = 4e-20
Identities = 67/253 (26%), Positives = 118/253 (46%), Gaps = 1/253 (0%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C SQV C A + VP+ L + L + + L F ++ L L ++ L+
Sbjct: 31 CSRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALRIEKNELS 90
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
RI P AFR L LR L + + L + F L ++ S++L+ N++ QI+ F+ +
Sbjct: 91 RITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSN 150
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLP 274
+ + L N ++ I AF L + ++ L + + I P+ F L + VL L L
Sbjct: 151 LKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLT 210
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
+ TF GL+ + L+L+++ +G++ G F ++ L + NN I + +Q
Sbjct: 211 DIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQ 270
Query: 335 VRVFKLTGNHMLE 347
+ L GN + E
Sbjct: 271 LNRLTLFGNSLKE 283
Score = 85.0 bits (201), Expect = 5e-16
Identities = 76/317 (23%), Positives = 137/317 (43%), Gaps = 10/317 (3%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSP---SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDAC 152
C + ++ + L +P G +T+L+L + L + F HL L+ L L
Sbjct: 148 CSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYEN 207
Query: 153 NLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAG 212
LT I F GL L+EL +Q + + F N+ + L++N I+Q+ F
Sbjct: 208 RLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQ 267
Query: 213 TNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFM 271
+N ++L N +K + + F + ++ ++ L + I ++ F+ L + VL L+
Sbjct: 268 LPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRN 327
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+ + P F+GL + LSL + L + F L ++ + + NN++ +
Sbjct: 328 QISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFAN 387
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVENII-IRGNHLPCECGRD--PFTNPLALSQDFAEE 388
N + +L N + P + + + +R P C D P N L L+Q
Sbjct: 388 VNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGT 447
Query: 389 N---YCISPLKVRGRSL 402
+ C SP VRG+SL
Sbjct: 448 DTVPVCFSPANVRGQSL 464
Score = 45.6 bits (103), Expect = 4e-04
Identities = 25/106 (23%), Positives = 52/106 (49%)
Query: 245 LPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGS 304
L + I + F + + L + +L + P F L + LSL + L ++ +G
Sbjct: 61 LNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGL 120
Query: 305 FDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
F GL +++L + +N++ I+ Q ++++ +L GNH+ P+
Sbjct: 121 FQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPD 166
>BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 96.3 bits (229), Expect = 2e-19
Identities = 67/232 (28%), Positives = 113/232 (48%), Gaps = 5/232 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+VVC L VP G+ + L+L +++++++D F HL L L L ++
Sbjct: 52 CSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSI 111
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+I AF GL L L + L + S AF L + + L +N I I SYAF
Sbjct: 112 RQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVP 171
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELPSGIRTIEPQA-FAGLEGIGVLELAFMD 272
+ + L ++ I AF GL ++ + L G+ I+ L G+ LE++
Sbjct: 172 SLMRLDLGELKKLEYISEGAFEGLFNLKYLNL--GMCNIKDMPNLTPLVGLEELEMSGNH 229
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
P + P +FHGL + +L + S + +I+ +FDGL + L + +N + +
Sbjct: 230 FPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSL 281
Score = 46.0 bits (104), Expect = 3e-04
Identities = 20/82 (24%), Positives = 43/82 (52%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
L L + + IRP +F GL L++L++ ++ ++ ++ AF L ++ + L HN ++
Sbjct: 220 LEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLS 279
Query: 204 QIESYAFAGTNFINLISLRNNP 225
+ F ++ + L +NP
Sbjct: 280 SLPHDLFTPLRYLVELHLHHNP 301
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/95 (25%), Positives = 45/95 (47%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L L ++ + DTF L + L L + + I+VG+F+GL ++TLE+ +N + I
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 326 ELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENII 360
+ + +R L N + P V +++
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLM 174
>BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 96.3 bits (229), Expect = 2e-19
Identities = 67/232 (28%), Positives = 113/232 (48%), Gaps = 5/232 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+VVC L VP G+ + L+L +++++++D F HL L L L ++
Sbjct: 52 CSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSI 111
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+I AF GL L L + L + S AF L + + L +N I I SYAF
Sbjct: 112 RQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVP 171
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELPSGIRTIEPQA-FAGLEGIGVLELAFMD 272
+ + L ++ I AF GL ++ + L G+ I+ L G+ LE++
Sbjct: 172 SLMRLDLGELKKLEYISEGAFEGLFNLKYLNL--GMCNIKDMPNLTPLVGLEELEMSGNH 229
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
P + P +FHGL + +L + S + +I+ +FDGL + L + +N + +
Sbjct: 230 FPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSL 281
Score = 46.0 bits (104), Expect = 3e-04
Identities = 20/82 (24%), Positives = 43/82 (52%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
L L + + IRP +F GL L++L++ ++ ++ ++ AF L ++ + L HN ++
Sbjct: 220 LEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLS 279
Query: 204 QIESYAFAGTNFINLISLRNNP 225
+ F ++ + L +NP
Sbjct: 280 SLPHDLFTPLRYLVELHLHHNP 301
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/95 (25%), Positives = 45/95 (47%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L L ++ + DTF L + L L + + I+VG+F+GL ++TLE+ +N + I
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 326 ELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENII 360
+ + +R L N + P V +++
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLM 174
>AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein.
Length = 653
Score = 96.3 bits (229), Expect = 2e-19
Identities = 67/232 (28%), Positives = 113/232 (48%), Gaps = 5/232 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+VVC L VP G+ + L+L +++++++D F HL L L L ++
Sbjct: 52 CSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSI 111
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+I AF GL L L + L + S AF L + + L +N I I SYAF
Sbjct: 112 RQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVP 171
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELPSGIRTIEPQA-FAGLEGIGVLELAFMD 272
+ + L ++ I AF GL ++ + L G+ I+ L G+ LE++
Sbjct: 172 SLMRLDLGELKKLEYISEGAFEGLFNLKYLNL--GMCNIKDMPNLTPLVGLEELEMSGNH 229
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
P + P +FHGL + +L + S + +I+ +FDGL + L + +N + +
Sbjct: 230 FPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSL 281
Score = 46.0 bits (104), Expect = 3e-04
Identities = 20/82 (24%), Positives = 43/82 (52%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
L L + + IRP +F GL L++L++ ++ ++ ++ AF L ++ + L HN ++
Sbjct: 220 LEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLS 279
Query: 204 QIESYAFAGTNFINLISLRNNP 225
+ F ++ + L +NP
Sbjct: 280 SLPHDLFTPLRYLVELHLHHNP 301
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/95 (25%), Positives = 45/95 (47%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L L ++ + DTF L + L L + + I+VG+F+GL ++TLE+ +N + I
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 326 ELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENII 360
+ + +R L N + P V +++
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLM 174
>AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens
cDNA FLJ23912 fis, clone CAE04210, highly similar to
Homo sapiens leucine rich repeat containing 4 (LRRC4).
).
Length = 653
Score = 96.3 bits (229), Expect = 2e-19
Identities = 67/232 (28%), Positives = 113/232 (48%), Gaps = 5/232 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+VVC L VP G+ + L+L +++++++D F HL L L L ++
Sbjct: 52 CSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSI 111
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+I AF GL L L + L + S AF L + + L +N I I SYAF
Sbjct: 112 RQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVP 171
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELPSGIRTIEPQA-FAGLEGIGVLELAFMD 272
+ + L ++ I AF GL ++ + L G+ I+ L G+ LE++
Sbjct: 172 SLMRLDLGELKKLEYISEGAFEGLFNLKYLNL--GMCNIKDMPNLTPLVGLEELEMSGNH 229
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
P + P +FHGL + +L + S + +I+ +FDGL + L + +N + +
Sbjct: 230 FPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSL 281
Score = 44.0 bits (99), Expect = 0.001
Identities = 19/82 (23%), Positives = 43/82 (52%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
L L + + IRP +F GL L++L++ ++ ++ ++ AF L ++ + L HN ++
Sbjct: 220 LEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLS 279
Query: 204 QIESYAFAGTNFINLISLRNNP 225
+ F ++ + L ++P
Sbjct: 280 SLPHDLFTPLRYLVELHLHHDP 301
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/95 (25%), Positives = 45/95 (47%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L L ++ + DTF L + L L + + I+VG+F+GL ++TLE+ +N + I
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 326 ELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENII 360
+ + +R L N + P V +++
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLM 174
>AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated
protein LRRC4 protein.
Length = 653
Score = 96.3 bits (229), Expect = 2e-19
Identities = 67/232 (28%), Positives = 113/232 (48%), Gaps = 5/232 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+VVC L VP G+ + L+L +++++++D F HL L L L ++
Sbjct: 52 CSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSI 111
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+I AF GL L L + L + S AF L + + L +N I I SYAF
Sbjct: 112 RQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVP 171
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELPSGIRTIEPQA-FAGLEGIGVLELAFMD 272
+ + L ++ I AF GL ++ + L G+ I+ L G+ LE++
Sbjct: 172 SLMRLDLGELKKLEYISEGAFEGLFNLKYLNL--GMCNIKDMPNLTPLVGLEELEMSGNH 229
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
P + P +FHGL + +L + S + +I+ +FDGL + L + +N + +
Sbjct: 230 FPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSL 281
Score = 46.0 bits (104), Expect = 3e-04
Identities = 20/82 (24%), Positives = 43/82 (52%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
L L + + IRP +F GL L++L++ ++ ++ ++ AF L ++ + L HN ++
Sbjct: 220 LEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLS 279
Query: 204 QIESYAFAGTNFINLISLRNNP 225
+ F ++ + L +NP
Sbjct: 280 SLPHDLFTPLRYLVELHLHHNP 301
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/95 (25%), Positives = 45/95 (47%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L L ++ + DTF L + L L + + I+VG+F+GL ++TLE+ +N + I
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 326 ELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENII 360
+ + +R L N + P V +++
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLM 174
>DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice
variant 3 protein.
Length = 640
Score = 93.1 bits (221), Expect = 2e-18
Identities = 66/229 (28%), Positives = 115/229 (50%), Gaps = 5/229 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+V+C LR VP G+S + L+L +++++ ++F HLR L L L ++
Sbjct: 53 CSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHI 112
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
I AF GL L L + L T+ + AF L + + L +N I I SYAF
Sbjct: 113 RTIEIGAFNGLANLNTLELFDNRLTTISNGAFVYLSKLKELWLRNNPIESIPSYAFNRIP 172
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMD 272
+ + L + I AF GL+++ + L +R I P L + L+L+
Sbjct: 173 SLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREI-PN-LTPLIKLDELDLSGNH 230
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L ++ P +F GL+ + +L + +S + +I+ +FD LQ + + + +N +
Sbjct: 231 LSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNL 279
Score = 81.4 bits (192), Expect = 6e-15
Identities = 67/235 (28%), Positives = 111/235 (47%), Gaps = 11/235 (4%)
Query: 145 RRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQ 204
R L L + I+ +F+ L L L + + T++ AF L N+ ++ L NR+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 205 IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRT--IEPQAFAGLEG 262
I + AF + + + LRNNPI+ I +AF+ + + +++L R I AF GL
Sbjct: 139 ISNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 263 IGVLELAFMDL---PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNN 319
+ L LA +L P+L P LI++ L L + L I+ GSF GL H+ L + +
Sbjct: 199 LRYLNLAMCNLREIPNLTP-----LIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQS 253
Query: 320 KIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI-IIRGNHLPCECGRD 373
+I IE + S+ L N++ P + + ++ I +H P C D
Sbjct: 254 QIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWSCNCD 308
Score = 51.6 bits (118), Expect = 6e-06
Identities = 34/115 (29%), Positives = 61/115 (53%), Gaps = 3/115 (2%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G GLS ++ L+L+ +LR + + L +L L L +L+ IRP +F+GL L++
Sbjct: 191 GAFEGLS-NLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQK 247
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L++ + + ++ AF LQ++ I L HN + + F + + I L +NP
Sbjct: 248 LWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNP 302
>BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 92.7 bits (220), Expect = 2e-18
Identities = 74/325 (22%), Positives = 140/325 (43%), Gaps = 7/325 (2%)
Query: 96 CLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C S Q V+C+ L+ +P +S L+L R + VL +++F + L L L C +
Sbjct: 29 CHSDLQHVICDKVGLQKIPK-VSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQI 87
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ AFRGL +L LY+ H + + + AF L +T + L HN++ ++ +
Sbjct: 88 REVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLV 147
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDL 273
+ ++ L NN I+ + AF G D+ + L + + +++P A +E + + L
Sbjct: 148 NLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQL 207
Query: 274 PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL-QHVDTLEICNNKIDGIEELSLVQN 332
S L V L L + L I +F ++++TL + N ++ + + +
Sbjct: 208 SSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGV 267
Query: 333 NSVRVFKLTGNHMLESPEAVVLE-VENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYC 391
+++ L N + + P + +E + + N C C L + C
Sbjct: 268 TTLKHVHLENNRLNQLPSNFPFDSLETLALTNNPWKCTCQLRGLRRWLEAKASRPDAT-C 326
Query: 392 ISPLKVRGRSLASATSGSAGCRGET 416
SP K +G+ + T C+ T
Sbjct: 327 ASPAKFKGQHIRD-TDAFRSCKFPT 350
>BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein.
Length = 640
Score = 92.7 bits (220), Expect = 2e-18
Identities = 66/229 (28%), Positives = 115/229 (50%), Gaps = 5/229 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+V+C LR VP G+S + L+L +++++ ++F HLR L L L ++
Sbjct: 53 CSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHI 112
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
I AF GL L L + L T+ + AF L + + L +N I I SYAF
Sbjct: 113 RTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIP 172
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMD 272
+ + L + I AF GL+++ + L +R I P L + L+L+
Sbjct: 173 SLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREI-PN-LTPLIKLDELDLSGNH 230
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L ++ P +F GL+ + +L + +S + +I+ +FD LQ + + + +N +
Sbjct: 231 LSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNL 279
Score = 81.0 bits (191), Expect = 8e-15
Identities = 67/235 (28%), Positives = 111/235 (47%), Gaps = 11/235 (4%)
Query: 145 RRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQ 204
R L L + I+ +F+ L L L + + T++ AF L N+ ++ L NR+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 205 IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRT--IEPQAFAGLEG 262
I + AF + + + LRNNPI+ I +AF+ + + +++L R I AF GL
Sbjct: 139 IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 263 IGVLELAFMDL---PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNN 319
+ L LA +L P+L P LI++ L L + L I+ GSF GL H+ L + +
Sbjct: 199 LRYLNLAMCNLREIPNLTP-----LIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQS 253
Query: 320 KIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI-IIRGNHLPCECGRD 373
+I IE + S+ L N++ P + + ++ I +H P C D
Sbjct: 254 QIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCD 308
Score = 51.6 bits (118), Expect = 6e-06
Identities = 34/115 (29%), Positives = 61/115 (53%), Gaps = 3/115 (2%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G GLS ++ L+L+ +LR + + L +L L L +L+ IRP +F+GL L++
Sbjct: 191 GAFEGLS-NLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQK 247
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L++ + + ++ AF LQ++ I L HN + + F + + I L +NP
Sbjct: 248 LWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNP 302
>BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 92.7 bits (220), Expect = 2e-18
Identities = 74/325 (22%), Positives = 140/325 (43%), Gaps = 7/325 (2%)
Query: 96 CLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C S Q V+C+ L+ +P +S L+L R + VL +++F + L L L C +
Sbjct: 29 CHSDLQHVICDKVGLQKIPK-VSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQI 87
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ AFRGL +L LY+ H + + + AF L +T + L HN++ ++ +
Sbjct: 88 REVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLV 147
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDL 273
+ ++ L NN I+ + AF G D+ + L + + +++P A +E + + L
Sbjct: 148 NLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQL 207
Query: 274 PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL-QHVDTLEICNNKIDGIEELSLVQN 332
S L V L L + L I +F ++++TL + N ++ + + +
Sbjct: 208 SSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGV 267
Query: 333 NSVRVFKLTGNHMLESPEAVVLE-VENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYC 391
+++ L N + + P + +E + + N C C L + C
Sbjct: 268 TTLKHVHLENNRLNQLPSNFPFDSLETLALTNNPWKCTCQLRGLRRWLEAKASRPDAT-C 326
Query: 392 ISPLKVRGRSLASATSGSAGCRGET 416
SP K +G+ + T C+ T
Sbjct: 327 ASPAKFKGQHIRD-TDAFRSCKFPT 350
>AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein.
Length = 640
Score = 92.7 bits (220), Expect = 2e-18
Identities = 66/229 (28%), Positives = 115/229 (50%), Gaps = 5/229 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+V+C LR VP G+S + L+L +++++ ++F HLR L L L ++
Sbjct: 53 CSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHI 112
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
I AF GL L L + L T+ + AF L + + L +N I I SYAF
Sbjct: 113 RTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIP 172
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMD 272
+ + L + I AF GL+++ + L +R I P L + L+L+
Sbjct: 173 SLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREI-PN-LTPLIKLDELDLSGNH 230
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L ++ P +F GL+ + +L + +S + +I+ +FD LQ + + + +N +
Sbjct: 231 LSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNL 279
Score = 81.0 bits (191), Expect = 8e-15
Identities = 67/235 (28%), Positives = 111/235 (47%), Gaps = 11/235 (4%)
Query: 145 RRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQ 204
R L L + I+ +F+ L L L + + T++ AF L N+ ++ L NR+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 205 IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRT--IEPQAFAGLEG 262
I + AF + + + LRNNPI+ I +AF+ + + +++L R I AF GL
Sbjct: 139 IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 263 IGVLELAFMDL---PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNN 319
+ L LA +L P+L P LI++ L L + L I+ GSF GL H+ L + +
Sbjct: 199 LRYLNLAMCNLREIPNLTP-----LIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQS 253
Query: 320 KIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI-IIRGNHLPCECGRD 373
+I IE + S+ L N++ P + + ++ I +H P C D
Sbjct: 254 QIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCD 308
Score = 51.6 bits (118), Expect = 6e-06
Identities = 34/115 (29%), Positives = 61/115 (53%), Gaps = 3/115 (2%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G GLS ++ L+L+ +LR + + L +L L L +L+ IRP +F+GL L++
Sbjct: 191 GAFEGLS-NLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQK 247
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L++ + + ++ AF LQ++ I L HN + + F + + I L +NP
Sbjct: 248 LWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNP 302
>AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 92.7 bits (220), Expect = 2e-18
Identities = 74/325 (22%), Positives = 140/325 (43%), Gaps = 7/325 (2%)
Query: 96 CLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C S Q V+C+ L+ +P +S L+L R + VL +++F + L L L C +
Sbjct: 29 CHSDLQHVICDKVGLQKIPK-VSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQI 87
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ AFRGL +L LY+ H + + + AF L +T + L HN++ ++ +
Sbjct: 88 REVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLV 147
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDL 273
+ ++ L NN I+ + AF G D+ + L + + +++P A +E + + L
Sbjct: 148 NLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQL 207
Query: 274 PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL-QHVDTLEICNNKIDGIEELSLVQN 332
S L V L L + L I +F ++++TL + N ++ + + +
Sbjct: 208 SSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGV 267
Query: 333 NSVRVFKLTGNHMLESPEAVVLE-VENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYC 391
+++ L N + + P + +E + + N C C L + C
Sbjct: 268 TTLKHVHLENNRLNQLPSNFPFDSLETLALTNNPWKCTCQLRGLRRWLEAKASRPDAT-C 326
Query: 392 ISPLKVRGRSLASATSGSAGCRGET 416
SP K +G+ + T C+ T
Sbjct: 327 ASPAKFKGQHIRD-TDAFRSCKFPT 350
>AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein.
Length = 640
Score = 92.7 bits (220), Expect = 2e-18
Identities = 66/229 (28%), Positives = 115/229 (50%), Gaps = 5/229 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+V+C LR VP G+S + L+L +++++ ++F HLR L L L ++
Sbjct: 53 CSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHI 112
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
I AF GL L L + L T+ + AF L + + L +N I I SYAF
Sbjct: 113 RTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIP 172
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMD 272
+ + L + I AF GL+++ + L +R I P L + L+L+
Sbjct: 173 SLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREI-PN-LTPLIKLDELDLSGNH 230
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L ++ P +F GL+ + +L + +S + +I+ +FD LQ + + + +N +
Sbjct: 231 LSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNL 279
Score = 81.0 bits (191), Expect = 8e-15
Identities = 67/235 (28%), Positives = 111/235 (47%), Gaps = 11/235 (4%)
Query: 145 RRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQ 204
R L L + I+ +F+ L L L + + T++ AF L N+ ++ L NR+
Sbjct: 79 RLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTT 138
Query: 205 IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRT--IEPQAFAGLEG 262
I + AF + + + LRNNPI+ I +AF+ + + +++L R I AF GL
Sbjct: 139 IPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSN 198
Query: 263 IGVLELAFMDL---PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNN 319
+ L LA +L P+L P LI++ L L + L I+ GSF GL H+ L + +
Sbjct: 199 LRYLNLAMCNLREIPNLTP-----LIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQS 253
Query: 320 KIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI-IIRGNHLPCECGRD 373
+I IE + S+ L N++ P + + ++ I +H P C D
Sbjct: 254 QIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCD 308
Score = 51.6 bits (118), Expect = 6e-06
Identities = 34/115 (29%), Positives = 61/115 (53%), Gaps = 3/115 (2%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G GLS ++ L+L+ +LR + + L +L L L +L+ IRP +F+GL L++
Sbjct: 191 GAFEGLS-NLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQK 247
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L++ + + ++ AF LQ++ I L HN + + F + + I L +NP
Sbjct: 248 LWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNP 302
>U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 91.9 bits (218), Expect = 4e-18
Identities = 74/325 (22%), Positives = 139/325 (42%), Gaps = 7/325 (2%)
Query: 96 CLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C S Q V+C+ L+ +P +S L+L R + VL +++F + L L L C +
Sbjct: 29 CHSDLQHVICDKVGLQKIPK-VSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQI 87
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ AFRGL +L LY+ H + V + AF L +T + L HN++ ++ +
Sbjct: 88 REVAAGAFRGLKQLIYLYLSHNDIRVVRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLV 147
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDL 273
+ ++ L NN I+ + F G D+ + L + + +++P A +E + + L
Sbjct: 148 NLFILQLNNNKIRELRAGPFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQL 207
Query: 274 PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL-QHVDTLEICNNKIDGIEELSLVQN 332
S L V L L + L I +F ++++TL + N ++ + + +
Sbjct: 208 SSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGV 267
Query: 333 NSVRVFKLTGNHMLESPEAVVLE-VENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYC 391
+++ L N + + P + +E + + N C C L + C
Sbjct: 268 TTLKHVHLENNRLNQLPSNFPFDSLETLALTNNPWKCTCQLRGLRRWLEAKASRPDAT-C 326
Query: 392 ISPLKVRGRSLASATSGSAGCRGET 416
SP K +G+ + T C+ T
Sbjct: 327 ASPAKFKGQHIRD-TDAFRSCKFPT 350
>DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice
variant 4 protein.
Length = 640
Score = 91.9 bits (218), Expect = 4e-18
Identities = 66/229 (28%), Positives = 115/229 (50%), Gaps = 5/229 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+V+C LRGVP G+S + L+L +++++ ++F HLR L L L ++
Sbjct: 53 CSNQFSKVICVRKNLRGVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHI 112
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
I AF G L + LAT+ + AF L + + L +N I I SYAF
Sbjct: 113 RTIEIGAFNGPANPNTLELFDNRLATIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIP 172
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMD 272
+ + L + I AF GL+++ + L +R I P L + L+L+
Sbjct: 173 SLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREI-PN-LTPLIKLDELDLSGNH 230
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L ++ P +F GL+ + +L + +S + +I+ +FD LQ + + + +N +
Sbjct: 231 LSAIRPGSFQGLMHLQKLWMIQSQIRVIERNAFDNLQSLVEINLAHNNL 279
Score = 51.6 bits (118), Expect = 6e-06
Identities = 34/115 (29%), Positives = 61/115 (53%), Gaps = 3/115 (2%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G GLS ++ L+L+ +LR + + L +L L L +L+ IRP +F+GL L++
Sbjct: 191 GAFEGLS-NLRYLNLAMCNLREIPN--LTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQK 247
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L++ + + ++ AF LQ++ I L HN + + F + + I L +NP
Sbjct: 248 LWMIQSQIRVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNP 302
Score = 34.3 bits (75), Expect = 0.90
Identities = 16/36 (44%), Positives = 24/36 (66%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L E+ + IIKV SF L+H++ L++ N I IE
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIE 116
>AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ45014 fis, clone BRAWH3014609. ).
Length = 518
Score = 91.9 bits (218), Expect = 4e-18
Identities = 73/309 (23%), Positives = 139/309 (44%), Gaps = 5/309 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S A G+P +S LSL ++ L+S+ FA L QL L LD ++ + A
Sbjct: 45 VYCESHAFAGIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDA 104
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F+G+ RL+EL + + + + F + N+ ++ L++N++ ++S F G + ++ L
Sbjct: 105 FQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHL 164
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N +K + + F ++ ++L + +R++ AFAGL + L L +
Sbjct: 165 RSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAH 224
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L + + L+ + + I G + L++ N I GIE + +++ L
Sbjct: 225 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 284
Query: 341 TGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPLK 396
N + + V + + +I + GN C P L + E C P
Sbjct: 285 DSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKH 344
Query: 397 VRGRSLASA 405
++G ++ A
Sbjct: 345 IQGEKVSDA 353
>BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein.
Length = 420
Score = 90.2 bits (214), Expect = 1e-17
Identities = 67/229 (29%), Positives = 111/229 (48%), Gaps = 5/229 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+V+C L VP+ + + L+L ++V+R+D F HLR L L L +
Sbjct: 63 CSNQASRVICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLV 122
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+I AF GLP L L + L TV + AF L + + L +N I I SYAF
Sbjct: 123 RKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVP 182
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELPSGIRTIEP-QAFAGLEGIGVLELAFMD 272
+ + L ++ I AF GL ++ + L G+ ++ L + LEL+
Sbjct: 183 SLRRLDLGELKRLEYISEAAFEGLVNLRYLNL--GMCNLKDIPNLTALVRLEELELSGNR 240
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L + P +F GL + +L L + + I+ +FD L+ ++ L + +N +
Sbjct: 241 LDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNL 289
Score = 75.4 bits (177), Expect = 4e-13
Identities = 58/232 (25%), Positives = 106/232 (45%), Gaps = 5/232 (2%)
Query: 145 RRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQ 204
R L L + IR F+ L L L + + ++ AF L ++ ++ L NR+
Sbjct: 89 RYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTT 148
Query: 205 IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPS--GIRTIEPQAFAGLEG 262
+ + AF + + + LRNNPI+ I +AF+ + + +++L + I AF GL
Sbjct: 149 VPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVN 208
Query: 263 IGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
+ L L +L + L+R+ L L + L +I+ GSF GL + L + + ++
Sbjct: 209 LRYLNLGMCNLKDI--PNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVA 266
Query: 323 GIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI-IIRGNHLPCECGRD 373
IE + S+ L+ N+++ P + + + + NH P C D
Sbjct: 267 TIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCD 318
Score = 54.4 bits (125), Expect = 8e-07
Identities = 27/85 (31%), Positives = 47/85 (55%)
Query: 141 LRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHN 200
L +L L L L IRP +F+GL LR+L++ H +AT++ AF L+++ + L+HN
Sbjct: 228 LVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHN 287
Query: 201 RIAQIESYAFAGTNFINLISLRNNP 225
+ + F + + + L +NP
Sbjct: 288 NLMSLPHDLFTPLHRLERVHLNHNP 312
Score = 31.9 bits (69), Expect = 4.8
Identities = 18/59 (30%), Positives = 28/59 (47%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
S+ +L L A + + +AF L+ L L L NL + F L RL +++ H P
Sbjct: 254 SLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNP 312
>BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for
IMAGE:5200456) protein.
Length = 634
Score = 90.2 bits (214), Expect = 1e-17
Identities = 67/229 (29%), Positives = 111/229 (48%), Gaps = 5/229 (2%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+V+C L VP+ + + L+L ++V+R+D F HLR L L L +
Sbjct: 63 CSNQASRVICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLV 122
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+I AF GLP L L + L TV + AF L + + L +N I I SYAF
Sbjct: 123 RKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVP 182
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELPSGIRTIEP-QAFAGLEGIGVLELAFMD 272
+ + L ++ I AF GL ++ + L G+ ++ L + LEL+
Sbjct: 183 SLRRLDLGELKRLEYISEAAFEGLVNLRYLNL--GMCNLKDIPNLTALVRLEELELSGNR 240
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L + P +F GL + +L L + + I+ +FD L+ ++ L + +N +
Sbjct: 241 LDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNL 289
Score = 75.4 bits (177), Expect = 4e-13
Identities = 58/232 (25%), Positives = 106/232 (45%), Gaps = 5/232 (2%)
Query: 145 RRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQ 204
R L L + IR F+ L L L + + ++ AF L ++ ++ L NR+
Sbjct: 89 RYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTT 148
Query: 205 IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPS--GIRTIEPQAFAGLEG 262
+ + AF + + + LRNNPI+ I +AF+ + + +++L + I AF GL
Sbjct: 149 VPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVN 208
Query: 263 IGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
+ L L +L + L+R+ L L + L +I+ GSF GL + L + + ++
Sbjct: 209 LRYLNLGMCNLKDI--PNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVA 266
Query: 323 GIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI-IIRGNHLPCECGRD 373
IE + S+ L+ N+++ P + + + + NH P C D
Sbjct: 267 TIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCD 318
Score = 54.4 bits (125), Expect = 8e-07
Identities = 27/85 (31%), Positives = 47/85 (55%)
Query: 141 LRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHN 200
L +L L L L IRP +F+GL LR+L++ H +AT++ AF L+++ + L+HN
Sbjct: 228 LVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHN 287
Query: 201 RIAQIESYAFAGTNFINLISLRNNP 225
+ + F + + + L +NP
Sbjct: 288 NLMSLPHDLFTPLHRLERVHLNHNP 312
Score = 31.9 bits (69), Expect = 4.8
Identities = 18/59 (30%), Positives = 28/59 (47%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
S+ +L L A + + +AF L+ L L L NL + F L RL +++ H P
Sbjct: 254 SLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNP 312
>BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 89.0 bits (211), Expect = 3e-17
Identities = 72/309 (23%), Positives = 138/309 (44%), Gaps = 5/309 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S A +P +S LSL ++ L+S+ FA L QL L LD ++ + A
Sbjct: 45 VYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDA 104
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F+G+ RL+EL + + + + F + N+ ++ L++N++ ++S F G + ++ L
Sbjct: 105 FQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHL 164
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N +K + + F ++ ++L + +R++ AFAGL + L L +
Sbjct: 165 RSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAH 224
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L + + L+ + + I G + L++ N I GIE + +++ L
Sbjct: 225 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 284
Query: 341 TGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPLK 396
N + + V + + +I + GN C P L + E C P
Sbjct: 285 DSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKH 344
Query: 397 VRGRSLASA 405
++G ++ A
Sbjct: 345 IQGEKVSDA 353
>BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 89.0 bits (211), Expect = 3e-17
Identities = 72/309 (23%), Positives = 138/309 (44%), Gaps = 5/309 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S A +P +S LSL ++ L+S+ FA L QL L LD ++ + A
Sbjct: 45 VYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDA 104
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F+G+ RL+EL + + + + F + N+ ++ L++N++ ++S F G + ++ L
Sbjct: 105 FQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHL 164
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N +K + + F ++ ++L + +R++ AFAGL + L L +
Sbjct: 165 RSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAH 224
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L + + L+ + + I G + L++ N I GIE + +++ L
Sbjct: 225 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 284
Query: 341 TGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPLK 396
N + + V + + +I + GN C P L + E C P
Sbjct: 285 DSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKH 344
Query: 397 VRGRSLASA 405
++G ++ A
Sbjct: 345 IQGEKVSDA 353
>BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 89.0 bits (211), Expect = 3e-17
Identities = 72/309 (23%), Positives = 138/309 (44%), Gaps = 5/309 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S A +P +S LSL ++ L+S+ FA L QL L LD ++ + A
Sbjct: 46 VYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDA 105
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F+G+ RL+EL + + + + F + N+ ++ L++N++ ++S F G + ++ L
Sbjct: 106 FQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHL 165
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N +K + + F ++ ++L + +R++ AFAGL + L L +
Sbjct: 166 RSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAH 225
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L + + L+ + + I G + L++ N I GIE + +++ L
Sbjct: 226 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 285
Query: 341 TGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPLK 396
N + + V + + +I + GN C P L + E C P
Sbjct: 286 DSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKH 345
Query: 397 VRGRSLASA 405
++G ++ A
Sbjct: 346 IQGEKVSDA 354
>BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 89.0 bits (211), Expect = 3e-17
Identities = 72/309 (23%), Positives = 138/309 (44%), Gaps = 5/309 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S A +P +S LSL ++ L+S+ FA L QL L LD ++ + A
Sbjct: 46 VYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDA 105
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F+G+ RL+EL + + + + F + N+ ++ L++N++ ++S F G + ++ L
Sbjct: 106 FQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHL 165
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N +K + + F ++ ++L + +R++ AFAGL + L L +
Sbjct: 166 RSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAH 225
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L + + L+ + + I G + L++ N I GIE + +++ L
Sbjct: 226 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 285
Query: 341 TGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPLK 396
N + + V + + +I + GN C P L + E C P
Sbjct: 286 DSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKH 345
Query: 397 VRGRSLASA 405
++G ++ A
Sbjct: 346 IQGEKVSDA 354
>AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein.
Length = 590
Score = 89.0 bits (211), Expect = 3e-17
Identities = 72/309 (23%), Positives = 138/309 (44%), Gaps = 5/309 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S A +P +S LSL ++ L+S+ FA L QL L LD ++ + A
Sbjct: 45 VYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDA 104
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F+G+ RL+EL + + + + F + N+ ++ L++N++ ++S F G + ++ L
Sbjct: 105 FQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHL 164
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N +K + + F ++ ++L + +R++ AFAGL + L L +
Sbjct: 165 RSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAH 224
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L + + L+ + + I G + L++ N I GIE + +++ L
Sbjct: 225 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 284
Query: 341 TGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPLK 396
N + + V + + +I + GN C P L + E C P
Sbjct: 285 DSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKH 344
Query: 397 VRGRSLASA 405
++G ++ A
Sbjct: 345 IQGEKVSDA 353
>AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat
transmembrane neuronal 4 protein protein.
Length = 518
Score = 89.0 bits (211), Expect = 3e-17
Identities = 72/309 (23%), Positives = 138/309 (44%), Gaps = 5/309 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S A +P +S LSL ++ L+S+ FA L QL L LD ++ + A
Sbjct: 45 VYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDA 104
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F+G+ RL+EL + + + + F + N+ ++ L++N++ ++S F G + ++ L
Sbjct: 105 FQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHL 164
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N +K + + F ++ ++L + +R++ AFAGL + L L +
Sbjct: 165 RSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAH 224
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L + + L+ + + I G + L++ N I GIE + +++ L
Sbjct: 225 FPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNL 284
Query: 341 TGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPLK 396
N + + V + + +I + GN C P L + E C P
Sbjct: 285 DSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKH 344
Query: 397 VRGRSLASA 405
++G ++ A
Sbjct: 345 IQGEKVSDA 353
>AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein
protein.
Length = 649
Score = 86.2 bits (204), Expect = 2e-16
Identities = 66/232 (28%), Positives = 110/232 (47%), Gaps = 9/232 (3%)
Query: 96 CLSQ-SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q S+VVC L VP G+ + L+L +++++++D F HL L L L ++
Sbjct: 52 CSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSI 111
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+I AF GL L L + L + S AF L + + L +N I I SYAF
Sbjct: 112 RQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVP 171
Query: 215 FINLISLRN-NPIKRILVHAFSGLNDVGQIELPSGIRTIEPQA-FAGLEGIGVLELAFMD 272
+ + L ++ I AF GL ++ + L G+ I+ L G+ LE++
Sbjct: 172 SLMRLDLGELKKLEYISEGAFEGLFNLKYLNL--GMCNIKDMPNLTPLVGLEELEMSGNH 229
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
P + P +FHGL + +L + S + +FDGL + L + +N + +
Sbjct: 230 FPEIRPGSFHGLSSLKKLWVMNSH----ERNAFDGLASLVELNLAHNNLSSL 277
Score = 37.1 bits (82), Expect = 0.13
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
L L + + IRP +F GL L++L++ ++ + AF L ++ + L HN ++
Sbjct: 220 LEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSH----ERNAFDGLASLVELNLAHNNLS 275
Query: 204 QIESYAFAGTNFINLISLRNNP 225
+ F ++ + L +NP
Sbjct: 276 SLPHDLFTPLRYLVELHLHHNP 297
Score = 33.9 bits (74), Expect = 1.2
Identities = 24/95 (25%), Positives = 45/95 (47%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L L ++ + DTF L + L L + + I+VG+F+GL ++TLE+ +N + I
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 326 ELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENII 360
+ + +R L N + P V +++
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLM 174
>AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich
repeat-containing G protein-coupled receptor 4 precursor
variant protein.
Length = 1032
Score = 85.8 bits (203), Expect = 3e-16
Identities = 76/272 (27%), Positives = 118/272 (43%), Gaps = 5/272 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C +V C+ L VP GLS L +S ++ L DAF + L L L +L+
Sbjct: 116 CDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLS 175
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
I P A GL L+ L +Q+ L TV S A L + S+ L N I + +F G
Sbjct: 176 FIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQ 235
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLP 274
+ + L +N + + VH S L + + L + I +I AF L + VL L +
Sbjct: 236 LRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIR 295
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
SL F GL + L L ++LG + L + L +N I I + + N
Sbjct: 296 SLSQHCFDGLDNLETLDLNYNNLGEFP-QAIKALPSLKELGFHSNSISVIPDGAFDGNPL 354
Query: 335 VRVFKLTGNHML---ESPEAVVLEVENIIIRG 363
+R L N + S + ++ +++IRG
Sbjct: 355 LRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRG 386
Score = 48.4 bits (110), Expect = 5e-05
Identities = 60/273 (21%), Positives = 112/273 (41%), Gaps = 12/273 (4%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L +R L F L L L L+ NL P A + LP L+EL +
Sbjct: 283 SLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEF-PQAIKALPSLKELGFHSNSI 341
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ + AF + +I L N ++ + + AF + ++ + +R +V F L
Sbjct: 342 SVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGAS----MVQQFPNLT 397
Query: 239 DVGQIE----LPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
+E + I +I + + L+L++ ++ L +F+G + +SL+
Sbjct: 398 GTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL--PSFNGCHALEEISLQR 455
Query: 295 SDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVL 354
+ + IK G+F GL + L++ N I I + + ++ N + P +
Sbjct: 456 NQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLN 515
Query: 355 EVENIIIRGN-HLPCECGRDPFTNPLALSQDFA 386
+ + + GN L F N +LS +A
Sbjct: 516 GLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYA 548
Score = 38.7 bits (86), Expect = 0.042
Identities = 30/152 (19%), Positives = 66/152 (43%), Gaps = 1/152 (0%)
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDL 273
F + + N I ++ AF + +++L + I P+A +GL+ + VL L L
Sbjct: 139 FTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQL 198
Query: 274 PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNN 333
++ + GL + L L + + + SF+GL + L + +N + + L
Sbjct: 199 KTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLP 258
Query: 334 SVRVFKLTGNHMLESPEAVVLEVENIIIRGNH 365
+++ L N + P+ + ++++ H
Sbjct: 259 TLQALTLALNKISSIPDFAFTNLSSLVVLHLH 290
>BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 85.4 bits (202), Expect = 4e-16
Identities = 75/321 (23%), Positives = 143/321 (44%), Gaps = 6/321 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S L+ +PS +S LSL L+ L+ + F L QL L LD +++ I A
Sbjct: 45 VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENA 104
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F G+ RL+EL + ++ + F + N+ ++ L++N++ + S F G + + L
Sbjct: 105 FNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHL 164
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N ++ I V F ++ ++L + IR++ FAG+ + L L L
Sbjct: 165 RSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLAL 224
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ-NNSVRVFK 339
F L+ + L L+ + + +I + L++ N+I+ S+ Q +++
Sbjct: 225 FPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLN 284
Query: 340 LTGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPL 395
L N + + ++ + + +I + GN C N L + E C SP
Sbjct: 285 LDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNICSLVNWLKSFKGLRENTIICASPK 344
Query: 396 KVRGRSLASATSGSAGCRGET 416
+++G ++ A + C T
Sbjct: 345 ELQGVNVIDAVKNYSICGKST 365
>BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 85.4 bits (202), Expect = 4e-16
Identities = 75/321 (23%), Positives = 143/321 (44%), Gaps = 6/321 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S L+ +PS +S LSL L+ L+ + F L QL L LD +++ I A
Sbjct: 45 VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENA 104
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F G+ RL+EL + ++ + F + N+ ++ L++N++ + S F G + + L
Sbjct: 105 FNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHL 164
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N ++ I V F ++ ++L + IR++ FAG+ + L L L
Sbjct: 165 RSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLAL 224
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ-NNSVRVFK 339
F L+ + L L+ + + +I + L++ N+I+ S+ Q +++
Sbjct: 225 FPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLN 284
Query: 340 LTGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPL 395
L N + + ++ + + +I + GN C N L + E C SP
Sbjct: 285 LDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNICSLVNWLKSFKGLRENTIICASPK 344
Query: 396 KVRGRSLASATSGSAGCRGET 416
+++G ++ A + C T
Sbjct: 345 ELQGVNVIDAVKNYSICGKST 365
>BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 85.4 bits (202), Expect = 4e-16
Identities = 75/321 (23%), Positives = 143/321 (44%), Gaps = 6/321 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S L+ +PS +S LSL L+ L+ + F L QL L LD +++ I A
Sbjct: 45 VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENA 104
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F G+ RL+EL + ++ + F + N+ ++ L++N++ + S F G + + L
Sbjct: 105 FNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHL 164
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N ++ I V F ++ ++L + IR++ FAG+ + L L L
Sbjct: 165 RSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLAL 224
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ-NNSVRVFK 339
F L+ + L L+ + + +I + L++ N+I+ S+ Q +++
Sbjct: 225 FPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLN 284
Query: 340 LTGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPL 395
L N + + ++ + + +I + GN C N L + E C SP
Sbjct: 285 LDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNICSLVNWLKSFKGLRENTIICASPK 344
Query: 396 KVRGRSLASATSGSAGCRGET 416
+++G ++ A + C T
Sbjct: 345 ELQGVNVIDAVKNYSICGKST 365
>AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein.
Length = 513
Score = 85.4 bits (202), Expect = 4e-16
Identities = 75/321 (23%), Positives = 143/321 (44%), Gaps = 6/321 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S L+ +PS +S LSL L+ L+ + F L QL L LD +++ I A
Sbjct: 45 VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENA 104
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F G+ RL+EL + ++ + F + N+ ++ L++N++ + S F G + + L
Sbjct: 105 FNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHL 164
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N ++ I V F ++ ++L + IR++ FAG+ + L L L
Sbjct: 165 RSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLAL 224
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ-NNSVRVFK 339
F L+ + L L+ + + +I + L++ N+I+ S+ Q +++
Sbjct: 225 FPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLN 284
Query: 340 LTGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPL 395
L N + + ++ + + +I + GN C N L + E C SP
Sbjct: 285 LDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNICSLVNWLKSFKGLRENTIICASPK 344
Query: 396 KVRGRSLASATSGSAGCRGET 416
+++G ++ A + C T
Sbjct: 345 ELQGVNVIDAVKNYSICGKST 365
>AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat
transmembrane neuronal 3 protein protein.
Length = 513
Score = 85.4 bits (202), Expect = 4e-16
Identities = 75/321 (23%), Positives = 143/321 (44%), Gaps = 6/321 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C S L+ +PS +S LSL L+ L+ + F L QL L LD +++ I A
Sbjct: 45 VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENA 104
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F G+ RL+EL + ++ + F + N+ ++ L++N++ + S F G + + L
Sbjct: 105 FNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHL 164
Query: 222 RNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
R+N ++ I V F ++ ++L + IR++ FAG+ + L L L
Sbjct: 165 RSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLAL 224
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ-NNSVRVFK 339
F L+ + L L+ + + +I + L++ N+I+ S+ Q +++
Sbjct: 225 FPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLN 284
Query: 340 LTGNHMLESPEAVV---LEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPL 395
L N + + ++ + + +I + GN C N L + E C SP
Sbjct: 285 LDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNICSLVNWLKSFKGLRENTIICASPK 344
Query: 396 KVRGRSLASATSGSAGCRGET 416
+++G ++ A + C T
Sbjct: 345 ELQGVNVIDAVKNYSICGKST 365
>BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein.
Length = 927
Score = 83.8 bits (198), Expect = 1e-15
Identities = 61/274 (22%), Positives = 120/274 (43%), Gaps = 4/274 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C +V C+ L VP GLS L L+ DL + A + L++L+ L L L
Sbjct: 35 CDGDRRVDCSGKGLTAVPEGLSAFTQALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLK 94
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ A RGL L+ L + + +V +F L + + L N + ++ + +
Sbjct: 95 TVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPT 154
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
+ ++L N I I AF+ L+ + + L + IR++ F GL+ + L+L + +L
Sbjct: 155 LQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLG 214
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
P L + L + + +I G+FDG + T+ + +N + + + +
Sbjct: 215 E-FPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSD 273
Query: 335 VRVFKLTGNHMLES-PEAV-VLEVENIIIRGNHL 366
+ + G M++ P + +E++ + G +
Sbjct: 274 LHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKI 307
Score = 48.4 bits (110), Expect = 5e-05
Identities = 60/273 (21%), Positives = 112/273 (41%), Gaps = 12/273 (4%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L +R L F L L L L+ NL P A + LP L+EL +
Sbjct: 178 SLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEF-PQAIKALPSLKELGFHSNSI 236
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ + AF + +I L N ++ + + AF + ++ + +R +V F L
Sbjct: 237 SVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGAS----MVQQFPNLT 292
Query: 239 DVGQIE----LPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
+E + I +I + + L+L++ ++ L +F+G + +SL+
Sbjct: 293 GTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL--PSFNGCHALEEISLQR 350
Query: 295 SDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVL 354
+ + IK G+F GL + L++ N I I + + ++ N + P +
Sbjct: 351 NQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLN 410
Query: 355 EVENIIIRGN-HLPCECGRDPFTNPLALSQDFA 386
+ + + GN L F N +LS +A
Sbjct: 411 GLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYA 443
>AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein.
Length = 622
Score = 83.0 bits (196), Expect = 2e-15
Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 3/217 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L +++ + AF LR L L L+ + R+ P F+GL LR LY+Q+ +
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ V F L ++ + L NR+ + S F G + ++ L NN I RI F L
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLE 204
Query: 239 DVGQIELPSGIRTIEP-QAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + L S T P AF L+ + L L+ + ++ P F GL + L L+ S +
Sbjct: 205 NLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRI 264
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGI--EELSLVQN 332
+ F G+ ++ L + +N ++ + + SL++N
Sbjct: 265 RNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKN 301
Score = 77.0 bits (181), Expect = 1e-13
Identities = 56/176 (31%), Positives = 89/176 (50%), Gaps = 2/176 (1%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
RGV + L SV L+L R L VL S F + LR L L N+ RI F+ L L
Sbjct: 149 RGVFNDLV-SVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLA 207
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI 229
LY+ L V S AF L+++ + L+HN I I+ +AF G + + L+N+ I+ +
Sbjct: 208 CLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNV 267
Query: 230 LVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGL 284
FSG+N++ + L + + + F+ L+ + L+L + S+ DTF +
Sbjct: 268 TRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENM 323
Score = 49.2 bits (112), Expect = 3e-05
Identities = 38/156 (24%), Positives = 72/156 (46%), Gaps = 1/156 (0%)
Query: 195 IVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIE 253
+ LT N I+ I G + + + L N+ I + AF L + + L + I+ ++
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 254 PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDT 313
P F GL + L L + + + F+ L+ V L+L+ + L ++ G+F G+ +
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 314 LEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L++ NN I I E ++ L N++ + P
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVP 220
Score = 48.4 bits (110), Expect = 5e-05
Identities = 39/180 (21%), Positives = 83/180 (46%), Gaps = 1/180 (0%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L L N++ I GL L LY+ ++ + V AF L+++ + L +N I +++
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGV 265
F G + + L+ N + + F+ L V + L + + + F G+ + +
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L+ ++ + F L + L L ++L + +F+ L+ + L + +N I+ I+
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244
Score = 45.6 bits (103), Expect = 4e-04
Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Query: 221 LRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
L N I I +GL+ + + L S I + P+AF L + L L + L P
Sbjct: 67 LTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPG 126
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
F GL+ + L L+ + + + G F+ L V L + N++ + + V ++R+
Sbjct: 127 IFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILD 186
Query: 340 LTGNHMLESPEAVVLEVENI 359
L+ N++L E+ +EN+
Sbjct: 187 LSNNNILRISESGFQHLENL 206
>AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein.
Length = 622
Score = 83.0 bits (196), Expect = 2e-15
Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 3/217 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L +++ + AF LR L L L+ + R+ P F+GL LR LY+Q+ +
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ V F L ++ + L NR+ + S F G + ++ L NN I RI F L
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLE 204
Query: 239 DVGQIELPSGIRTIEP-QAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + L S T P AF L+ + L L+ + ++ P F GL + L L+ S +
Sbjct: 205 NLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRI 264
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGI--EELSLVQN 332
+ F G+ ++ L + +N ++ + + SL++N
Sbjct: 265 RNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKN 301
Score = 77.0 bits (181), Expect = 1e-13
Identities = 56/176 (31%), Positives = 89/176 (50%), Gaps = 2/176 (1%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
RGV + L SV L+L R L VL S F + LR L L N+ RI F+ L L
Sbjct: 149 RGVFNDLV-SVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLA 207
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI 229
LY+ L V S AF L+++ + L+HN I I+ +AF G + + L+N+ I+ +
Sbjct: 208 CLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNV 267
Query: 230 LVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGL 284
FSG+N++ + L + + + F+ L+ + L+L + S+ DTF +
Sbjct: 268 TRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENM 323
Score = 49.2 bits (112), Expect = 3e-05
Identities = 38/156 (24%), Positives = 72/156 (46%), Gaps = 1/156 (0%)
Query: 195 IVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIE 253
+ LT N I+ I G + + + L N+ I + AF L + + L + I+ ++
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 254 PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDT 313
P F GL + L L + + + F+ L+ V L+L+ + L ++ G+F G+ +
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 314 LEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L++ NN I I E ++ L N++ + P
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVP 220
Score = 48.4 bits (110), Expect = 5e-05
Identities = 39/180 (21%), Positives = 83/180 (46%), Gaps = 1/180 (0%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L L N++ I GL L LY+ ++ + V AF L+++ + L +N I +++
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGV 265
F G + + L+ N + + F+ L V + L + + + F G+ + +
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L+ ++ + F L + L L ++L + +F+ L+ + L + +N I+ I+
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244
Score = 45.6 bits (103), Expect = 4e-04
Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Query: 221 LRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
L N I I +GL+ + + L S I + P+AF L + L L + L P
Sbjct: 67 LTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPG 126
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
F GL+ + L L+ + + + G F+ L V L + N++ + + V ++R+
Sbjct: 127 IFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILD 186
Query: 340 LTGNHMLESPEAVVLEVENI 359
L+ N++L E+ +EN+
Sbjct: 187 LSNNNILRISESGFQHLENL 206
>AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ41026 fis, clone BRAMY2004771, weakly similar
to CHONDROADHERIN PRECURSOR. ).
Length = 622
Score = 83.0 bits (196), Expect = 2e-15
Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 3/217 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L +++ + AF LR L L L+ + R+ P F+GL LR LY+Q+ +
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ V F L ++ + L NR+ + S F G + ++ L NN I RI F L
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLE 204
Query: 239 DVGQIELPSGIRTIEP-QAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + L S T P AF L+ + L L+ + ++ P F GL + L L+ S +
Sbjct: 205 NLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRI 264
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGI--EELSLVQN 332
+ F G+ ++ L + +N ++ + + SL++N
Sbjct: 265 RNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKN 301
Score = 77.0 bits (181), Expect = 1e-13
Identities = 56/176 (31%), Positives = 89/176 (50%), Gaps = 2/176 (1%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
RGV + L SV L+L R L VL S F + LR L L N+ RI F+ L L
Sbjct: 149 RGVFNDLV-SVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLA 207
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI 229
LY+ L V S AF L+++ + L+HN I I+ +AF G + + L+N+ I+ +
Sbjct: 208 CLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNV 267
Query: 230 LVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGL 284
FSG+N++ + L + + + F+ L+ + L+L + S+ DTF +
Sbjct: 268 TRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENM 323
Score = 49.2 bits (112), Expect = 3e-05
Identities = 38/156 (24%), Positives = 72/156 (46%), Gaps = 1/156 (0%)
Query: 195 IVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIE 253
+ LT N I+ I G + + + L N+ I + AF L + + L + I+ ++
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 254 PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDT 313
P F GL + L L + + + F+ L+ V L+L+ + L ++ G+F G+ +
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 314 LEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L++ NN I I E ++ L N++ + P
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVP 220
Score = 48.4 bits (110), Expect = 5e-05
Identities = 39/180 (21%), Positives = 83/180 (46%), Gaps = 1/180 (0%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L L N++ I GL L LY+ ++ + V AF L+++ + L +N I +++
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLD 124
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGV 265
F G + + L+ N + + F+ L V + L + + + F G+ + +
Sbjct: 125 PGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRI 184
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L+ ++ + F L + L L ++L + +F+ L+ + L + +N I+ I+
Sbjct: 185 LDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQ 244
Score = 45.6 bits (103), Expect = 4e-04
Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Query: 221 LRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
L N I I +GL+ + + L S I + P+AF L + L L + L P
Sbjct: 67 LTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPG 126
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
F GL+ + L L+ + + + G F+ L V L + N++ + + V ++R+
Sbjct: 127 IFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILD 186
Query: 340 LTGNHMLESPEAVVLEVENI 359
L+ N++L E+ +EN+
Sbjct: 187 LSNNNILRISESGFQHLENL 206
>AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple receptor
protein.
Length = 951
Score = 82.6 bits (195), Expect = 3e-15
Identities = 62/204 (30%), Positives = 91/204 (44%), Gaps = 1/204 (0%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C +V C+ L VP GLS L +S ++ L DAF + L L L +L+
Sbjct: 35 CDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLS 94
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
I P A GL L+ L +Q+ L TV S A L + S+ L N I + +F G
Sbjct: 95 FIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQ 154
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLP 274
+ + L +N + + VH S L + + L + I +I AF L + VL L +
Sbjct: 155 LRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIR 214
Query: 275 SLLPDTFHGLIRVGRLSLRESDLG 298
L F GL + L L ++LG
Sbjct: 215 GLSQHCFDGLDNLETLDLSYNNLG 238
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/148 (26%), Positives = 69/148 (46%), Gaps = 1/148 (0%)
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQ 255
++ N I Q+ AF F+ + L N + I A SGL ++ + L + ++T+ +
Sbjct: 64 ISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSE 123
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLE 315
A GL + L L + S+ D+F GL+++ L L ++ L + V L + L
Sbjct: 124 AIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALT 183
Query: 316 ICNNKIDGIEELSLVQNNSVRVFKLTGN 343
+ NKI I + + +S+ V L N
Sbjct: 184 LALNKISSIPDFAFTNLSSLVVLHLHNN 211
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/169 (23%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Query: 185 AFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIE 244
AF + + L N ++ I A +G + +++L+NN +K + A GL+ + +
Sbjct: 76 AFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLR 135
Query: 245 LPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVG 303
L + I ++ +F GL + L L L + L + L+L + + I
Sbjct: 136 LDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDF 195
Query: 304 SFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV 352
+F L + L + NNKI G+ + +++ L+ N++ E P+A+
Sbjct: 196 AFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAI 244
Score = 45.2 bits (102), Expect = 5e-04
Identities = 59/273 (21%), Positives = 110/273 (40%), Gaps = 12/273 (4%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L +R L F L L L L NL P A + P L+EL +
Sbjct: 202 SLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEF-PQAIKARPSLKELGFHSNSI 260
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ + AF + +I L N ++ + + AF + ++ + +R +V F L
Sbjct: 261 SVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGAS----MVQQFPNLT 316
Query: 239 DVGQIE----LPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
+E + I +I + + L+L++ ++ L +F+G + +SL+
Sbjct: 317 GTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL--PSFNGCHALEEISLQR 374
Query: 295 SDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVL 354
+ + IK G+F GL + L++ N I I + + ++ N + P +
Sbjct: 375 NQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLN 434
Query: 355 EVENIIIRGN-HLPCECGRDPFTNPLALSQDFA 386
+ + + GN L F N +LS +A
Sbjct: 435 GLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYA 467
Score = 38.7 bits (86), Expect = 0.042
Identities = 30/152 (19%), Positives = 66/152 (43%), Gaps = 1/152 (0%)
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDL 273
F + + N I ++ AF + +++L + I P+A +GL+ + VL L L
Sbjct: 58 FTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQL 117
Query: 274 PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNN 333
++ + GL + L L + + + SF+GL + L + +N + + L
Sbjct: 118 KTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLP 177
Query: 334 SVRVFKLTGNHMLESPEAVVLEVENIIIRGNH 365
+++ L N + P+ + ++++ H
Sbjct: 178 TLQALTLALNKISSIPDFAFTNLSSLVVLHLH 209
>AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled receptor
48 protein.
Length = 951
Score = 82.6 bits (195), Expect = 3e-15
Identities = 62/204 (30%), Positives = 91/204 (44%), Gaps = 1/204 (0%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C +V C+ L VP GLS L +S ++ L DAF + L L L +L+
Sbjct: 35 CDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLS 94
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
I P A GL L+ L +Q+ L TV S A L + S+ L N I + +F G
Sbjct: 95 FIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQ 154
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLP 274
+ + L +N + + VH S L + + L + I +I AF L + VL L +
Sbjct: 155 LRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIR 214
Query: 275 SLLPDTFHGLIRVGRLSLRESDLG 298
L F GL + L L ++LG
Sbjct: 215 GLSQHCFDGLDNLETLDLSYNNLG 238
Score = 59.7 bits (138), Expect = 2e-08
Identities = 39/148 (26%), Positives = 69/148 (46%), Gaps = 1/148 (0%)
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQ 255
++ N I Q+ AF F+ + L N + I A SGL ++ + L + ++T+ +
Sbjct: 64 ISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSE 123
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLE 315
A GL + L L + S+ D+F GL+++ L L ++ L + V L + L
Sbjct: 124 AIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALT 183
Query: 316 ICNNKIDGIEELSLVQNNSVRVFKLTGN 343
+ NKI I + + +S+ V L N
Sbjct: 184 LALNKISSIPDFAFTNLSSLVVLHLHNN 211
Score = 49.6 bits (113), Expect = 2e-05
Identities = 39/169 (23%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Query: 185 AFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIE 244
AF + + L N ++ I A +G + +++L+NN +K + A GL+ + +
Sbjct: 76 AFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLR 135
Query: 245 LPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVG 303
L + I ++ +F GL + L L L + L + L+L + + I
Sbjct: 136 LDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDF 195
Query: 304 SFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV 352
+F L + L + NNKI G+ + +++ L+ N++ E P+A+
Sbjct: 196 AFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAI 244
Score = 40.7 bits (91), Expect = 0.010
Identities = 58/273 (21%), Positives = 108/273 (39%), Gaps = 12/273 (4%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L +R L F L L L L NL P A + P L+EL +
Sbjct: 202 SLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEF-PQAIKARPSLKELGFHSNSI 260
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ + AF + +I L N ++ + + A + ++ + +R +V F L
Sbjct: 261 SVIPDGAFDGNPLLRTIHLYDNPLSFVGNSASHNLSDLHSLVIRGAS----MVQQFPNLT 316
Query: 239 DVGQIE----LPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
+E + I +I + + L+L++ ++ L +F+G + +SL+
Sbjct: 317 GTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL--PSFNGCHALEEISLQR 374
Query: 295 SDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVL 354
+ + IK G+F GL + L++ N I I + + ++ N + P
Sbjct: 375 NQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGPN 434
Query: 355 EVENIIIRGN-HLPCECGRDPFTNPLALSQDFA 386
+ + + GN L F N +LS +A
Sbjct: 435 GLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYA 467
Score = 38.7 bits (86), Expect = 0.042
Identities = 30/152 (19%), Positives = 66/152 (43%), Gaps = 1/152 (0%)
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDL 273
F + + N I ++ AF + +++L + I P+A +GL+ + VL L L
Sbjct: 58 FTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQL 117
Query: 274 PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNN 333
++ + GL + L L + + + SF+GL + L + +N + + L
Sbjct: 118 KTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLP 177
Query: 334 SVRVFKLTGNHMLESPEAVVLEVENIIIRGNH 365
+++ L N + P+ + ++++ H
Sbjct: 178 TLQALTLALNKISSIPDFAFTNLSSLVVLHLH 209
>BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein.
Length = 614
Score = 81.4 bits (192), Expect = 6e-15
Identities = 53/199 (26%), Positives = 94/199 (47%), Gaps = 2/199 (1%)
Query: 96 CLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q + V+C+ VP G+ L L + ++ L D FA L L L+ +
Sbjct: 42 CSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIV 101
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + P AF L LR L ++ L + F L N+T + ++ N+I + Y F
Sbjct: 102 SAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLY 161
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDL 273
+ + + +N + I AFSGLN + Q+ L + +I +A + L G+ VL L +++
Sbjct: 162 NLRSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNI 221
Query: 274 PSLLPDTFHGLIRVGRLSL 292
++ +F L R+ L +
Sbjct: 222 NAIRDYSFKRLYRLKVLEI 240
Score = 74.5 bits (175), Expect = 7e-13
Identities = 57/186 (30%), Positives = 93/186 (50%), Gaps = 4/186 (2%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL+ S+ QL+L + +L + ++A +HL L L L N+ IR ++F+ L RL+ L I
Sbjct: 182 SGLN-SLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 240
Query: 174 QHTP-LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH 232
H P L T+ L N+TS+ +TH + + A ++ ++L N I I
Sbjct: 241 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNRISTIEGS 299
Query: 233 AFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLS 291
L + +I+L G + +EP AF GL + VL ++ L +L FH + + L
Sbjct: 300 MLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 359
Query: 292 LRESDL 297
L + L
Sbjct: 360 LDSNPL 365
Score = 65.3 bits (152), Expect = 4e-10
Identities = 51/217 (23%), Positives = 99/217 (45%), Gaps = 2/217 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
GV +GLS ++T+L +S + +L F L LR L + +L I AF GL L +
Sbjct: 131 GVFTGLS-NLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSLEQ 189
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP-IKRI 229
L ++ L ++ + A + L + + L H I I Y+F + ++ + + P + +
Sbjct: 190 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTM 249
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
+ GLN + + A L + L L++ + ++ H L+R+
Sbjct: 250 TPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNRISTIEGSMLHELLRLQE 309
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
+ L L +++ +F GL ++ L + N++ +EE
Sbjct: 310 IQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEE 346
Score = 44.0 bits (99), Expect = 0.001
Identities = 39/158 (24%), Positives = 68/158 (43%), Gaps = 2/158 (1%)
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELPSGI-RTIEPQAFAGLEGIGVLELAFMDLPSL 276
L+ L N IK + F+ + ++EL I +EP AF L + L L L +
Sbjct: 69 LLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLI 128
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
F GL + +L + E+ + I+ F L ++ +LE+ +N + I + NS+
Sbjct: 129 PLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSLE 188
Query: 337 VFKLTGNHMLESPEAVVLEVEN-IIIRGNHLPCECGRD 373
L ++ P + + I++R HL RD
Sbjct: 189 QLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRD 226
Score = 43.2 bits (97), Expect = 0.002
Identities = 23/81 (28%), Positives = 41/81 (50%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L+LS + + L +L+ + L L + P+AFRGL LR L + L T++
Sbjct: 286 LNLSYNRISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLE 345
Query: 183 SFAFAALQNITSIVLTHNRIA 203
F ++ N+ +++L N +A
Sbjct: 346 ESVFHSVGNLETLILDSNPLA 366
>BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and Ig
domain containing 1 protein.
Length = 620
Score = 81.4 bits (192), Expect = 6e-15
Identities = 53/199 (26%), Positives = 94/199 (47%), Gaps = 2/199 (1%)
Query: 96 CLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q + V+C+ VP G+ L L + ++ L D FA L L L+ +
Sbjct: 48 CSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIV 107
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + P AF L LR L ++ L + F L N+T + ++ N+I + Y F
Sbjct: 108 SAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLY 167
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDL 273
+ + + +N + I AFSGLN + Q+ L + +I +A + L G+ VL L +++
Sbjct: 168 NLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNI 227
Query: 274 PSLLPDTFHGLIRVGRLSL 292
++ +F L R+ L +
Sbjct: 228 NAIRDYSFKRLYRLKVLEI 246
Score = 78.2 bits (184), Expect = 6e-14
Identities = 58/186 (31%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL+ S+ QL+L + +L + ++A +HL L L L N+ IR ++F+ L RL+ L I
Sbjct: 188 SGLN-SLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
Query: 174 QHTP-LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH 232
H P L T+ L N+TS+ +TH + + A ++ ++L NPI I
Sbjct: 247 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGS 305
Query: 233 AFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLS 291
L + +I+L G + +EP AF GL + VL ++ L +L FH + + L
Sbjct: 306 MLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 365
Query: 292 LRESDL 297
L + L
Sbjct: 366 LDSNPL 371
Score = 64.5 bits (150), Expect = 7e-10
Identities = 50/217 (23%), Positives = 99/217 (45%), Gaps = 2/217 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
GV +GLS ++T+L +S + +L F L L+ L + +L I AF GL L +
Sbjct: 137 GVFTGLS-NLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 195
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP-IKRI 229
L ++ L ++ + A + L + + L H I I Y+F + ++ + + P + +
Sbjct: 196 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTM 255
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
+ GLN + + A L + L L++ + ++ H L+R+
Sbjct: 256 TPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQE 315
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
+ L L +++ +F GL ++ L + N++ +EE
Sbjct: 316 IQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEE 352
Score = 44.4 bits (100), Expect = 8e-04
Identities = 39/158 (24%), Positives = 68/158 (43%), Gaps = 2/158 (1%)
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELPSGI-RTIEPQAFAGLEGIGVLELAFMDLPSL 276
L+ L N IK + F+ + ++EL I +EP AF L + L L L +
Sbjct: 75 LLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLI 134
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
F GL + +L + E+ + I+ F L ++ +LE+ +N + I + NS+
Sbjct: 135 PLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLE 194
Query: 337 VFKLTGNHMLESPEAVVLEVEN-IIIRGNHLPCECGRD 373
L ++ P + + I++R HL RD
Sbjct: 195 QLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRD 232
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/81 (28%), Positives = 41/81 (50%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L+LS + + L +L+ + L L + P+AFRGL LR L + L T++
Sbjct: 292 LNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLE 351
Query: 183 SFAFAALQNITSIVLTHNRIA 203
F ++ N+ +++L N +A
Sbjct: 352 ESVFHSVGNLETLILDSNPLA 372
>AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 620
Score = 81.4 bits (192), Expect = 6e-15
Identities = 53/199 (26%), Positives = 94/199 (47%), Gaps = 2/199 (1%)
Query: 96 CLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q + V+C+ VP G+ L L + ++ L D FA L L L+ +
Sbjct: 48 CSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIV 107
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + P AF L LR L ++ L + F L N+T + ++ N+I + Y F
Sbjct: 108 SAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLY 167
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDL 273
+ + + +N + I AFSGLN + Q+ L + +I +A + L G+ VL L +++
Sbjct: 168 NLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNI 227
Query: 274 PSLLPDTFHGLIRVGRLSL 292
++ +F L R+ L +
Sbjct: 228 NAIRDYSFKRLYRLKVLEI 246
Score = 78.2 bits (184), Expect = 6e-14
Identities = 58/186 (31%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL+ S+ QL+L + +L + ++A +HL L L L N+ IR ++F+ L RL+ L I
Sbjct: 188 SGLN-SLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
Query: 174 QHTP-LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH 232
H P L T+ L N+TS+ +TH + + A ++ ++L NPI I
Sbjct: 247 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGS 305
Query: 233 AFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLS 291
L + +I+L G + +EP AF GL + VL ++ L +L FH + + L
Sbjct: 306 MLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 365
Query: 292 LRESDL 297
L + L
Sbjct: 366 LDSNPL 371
Score = 64.5 bits (150), Expect = 7e-10
Identities = 50/217 (23%), Positives = 99/217 (45%), Gaps = 2/217 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
GV +GLS ++T+L +S + +L F L L+ L + +L I AF GL L +
Sbjct: 137 GVFTGLS-NLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 195
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP-IKRI 229
L ++ L ++ + A + L + + L H I I Y+F + ++ + + P + +
Sbjct: 196 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTM 255
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
+ GLN + + A L + L L++ + ++ H L+R+
Sbjct: 256 TPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQE 315
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
+ L L +++ +F GL ++ L + N++ +EE
Sbjct: 316 IQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEE 352
Score = 44.4 bits (100), Expect = 8e-04
Identities = 39/158 (24%), Positives = 68/158 (43%), Gaps = 2/158 (1%)
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELPSGI-RTIEPQAFAGLEGIGVLELAFMDLPSL 276
L+ L N IK + F+ + ++EL I +EP AF L + L L L +
Sbjct: 75 LLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLI 134
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
F GL + +L + E+ + I+ F L ++ +LE+ +N + I + NS+
Sbjct: 135 PLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLE 194
Query: 337 VFKLTGNHMLESPEAVVLEVEN-IIIRGNHLPCECGRD 373
L ++ P + + I++R HL RD
Sbjct: 195 QLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRD 232
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/81 (28%), Positives = 41/81 (50%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L+LS + + L +L+ + L L + P+AFRGL LR L + L T++
Sbjct: 292 LNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLE 351
Query: 183 SFAFAALQNITSIVLTHNRIA 203
F ++ N+ +++L N +A
Sbjct: 352 ESVFHSVGNLETLILDSNPLA 372
>AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein
protein.
Length = 577
Score = 81.4 bits (192), Expect = 6e-15
Identities = 53/199 (26%), Positives = 94/199 (47%), Gaps = 2/199 (1%)
Query: 96 CLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q + V+C+ VP G+ L L + ++ L D FA L L L+ +
Sbjct: 5 CSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIV 64
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + P AF L LR L ++ L + F L N+T + ++ N+I + Y F
Sbjct: 65 SAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLY 124
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDL 273
+ + + +N + I AFSGLN + Q+ L + +I +A + L G+ VL L +++
Sbjct: 125 NLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNI 184
Query: 274 PSLLPDTFHGLIRVGRLSL 292
++ +F L R+ L +
Sbjct: 185 NAIRDYSFKRLYRLKVLEI 203
Score = 78.2 bits (184), Expect = 6e-14
Identities = 58/186 (31%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL+ S+ QL+L + +L + ++A +HL L L L N+ IR ++F+ L RL+ L I
Sbjct: 145 SGLN-SLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 203
Query: 174 QHTP-LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH 232
H P L T+ L N+TS+ +TH + + A ++ ++L NPI I
Sbjct: 204 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGS 262
Query: 233 AFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLS 291
L + +I+L G + +EP AF GL + VL ++ L +L FH + + L
Sbjct: 263 MLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 322
Query: 292 LRESDL 297
L + L
Sbjct: 323 LDSNPL 328
Score = 64.5 bits (150), Expect = 7e-10
Identities = 50/217 (23%), Positives = 99/217 (45%), Gaps = 2/217 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
GV +GLS ++T+L +S + +L F L L+ L + +L I AF GL L +
Sbjct: 94 GVFTGLS-NLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 152
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP-IKRI 229
L ++ L ++ + A + L + + L H I I Y+F + ++ + + P + +
Sbjct: 153 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTM 212
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
+ GLN + + A L + L L++ + ++ H L+R+
Sbjct: 213 TPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQE 272
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
+ L L +++ +F GL ++ L + N++ +EE
Sbjct: 273 IQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEE 309
Score = 44.4 bits (100), Expect = 8e-04
Identities = 39/158 (24%), Positives = 68/158 (43%), Gaps = 2/158 (1%)
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELPSGI-RTIEPQAFAGLEGIGVLELAFMDLPSL 276
L+ L N IK + F+ + ++EL I +EP AF L + L L L +
Sbjct: 32 LLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLI 91
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
F GL + +L + E+ + I+ F L ++ +LE+ +N + I + NS+
Sbjct: 92 PLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLE 151
Query: 337 VFKLTGNHMLESPEAVVLEVEN-IIIRGNHLPCECGRD 373
L ++ P + + I++R HL RD
Sbjct: 152 QLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRD 189
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/81 (28%), Positives = 41/81 (50%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L+LS + + L +L+ + L L + P+AFRGL LR L + L T++
Sbjct: 249 LNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLE 308
Query: 183 SFAFAALQNITSIVLTHNRIA 203
F ++ N+ +++L N +A
Sbjct: 309 ESVFHSVGNLETLILDSNPLA 329
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 80.6 bits (190), Expect = 1e-14
Identities = 56/233 (24%), Positives = 117/233 (50%), Gaps = 4/233 (1%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P +TQL L+R +R++ F L L L L N++++ AF GL ++ L++++
Sbjct: 211 PRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNS 270
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
L V+S + L + + L++N IA+I ++ ++ + L N + R+ + + L
Sbjct: 271 LVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAEL 330
Query: 238 NDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT---FHGLIRVGRLSLR 293
+ + + L + I I AF GL + VL+L ++ + DT F GL + +L+L
Sbjct: 331 SSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLF 390
Query: 294 ESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHML 346
+ + + +F GL+ ++ L + N I ++ + V+ +++ ++ + L
Sbjct: 391 GNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFL 443
Score = 74.9 bits (176), Expect = 5e-13
Identities = 66/247 (26%), Positives = 111/247 (44%), Gaps = 5/247 (2%)
Query: 101 QVVCNSAALRGVPS--GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIR 158
+V N+ L VPS S V L L +R + L L L N+T +R
Sbjct: 96 EVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVR 155
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAAL-QNITSIVLTHNRIAQIESYAFAGTNFIN 217
F P ++EL + + T++ AF L +++ ++ L+ NRI Q+ AF
Sbjct: 156 NTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQ 215
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL 276
L L N I+ I F GLN + ++L + I + AF GL + VL L + L +
Sbjct: 216 L-DLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEV 274
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
+ +GL + +L L + + I + Q + L + N + ++E SL + +S+
Sbjct: 275 NSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLS 334
Query: 337 VFKLTGN 343
V +L+ N
Sbjct: 335 VLRLSHN 341
Score = 70.9 bits (166), Expect = 8e-12
Identities = 58/227 (25%), Positives = 111/227 (48%), Gaps = 4/227 (1%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHL-RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHT 176
P + +L+L+ + L AF L R L L L +T++ AF+ LPRL +L +
Sbjct: 163 PPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRN 221
Query: 177 PLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSG 236
+ ++ F L ++ + L N I+++ AF G + ++++ L N + + + G
Sbjct: 222 RIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYG 281
Query: 237 LNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRES 295
L + Q+ L + I I + ++ + + L L+F +L L ++ L + L L +
Sbjct: 282 LTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHN 341
Query: 296 DLGIIKVGSFDGLQHVDTLEICNNKIDG-IEELSLVQNNSVRVFKLT 341
+ I G+F GL+ + L++ +N+I G IE+ S + + KLT
Sbjct: 342 SISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLT 388
Score = 64.5 bits (150), Expect = 7e-10
Identities = 54/205 (26%), Positives = 94/205 (45%), Gaps = 4/205 (1%)
Query: 145 RRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQ 204
R L L L+ I P F LP L+E+Y+ + L V S AA ++ S+ L HN+I
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLG-AASSHVVSLFLQHNKIRS 129
Query: 205 IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL-EG 262
+E + ++ L N I + F + ++ L I T+E AF GL
Sbjct: 130 VEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRS 189
Query: 263 IGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
+ L L+ + + LP L R+ +L L + + +I+ +F GL ++ L++ N I
Sbjct: 190 LLTLRLS-KNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNIS 248
Query: 323 GIEELSLVQNNSVRVFKLTGNHMLE 347
+ + + + + V L N ++E
Sbjct: 249 KLTDGAFWGLSKMHVLHLEYNSLVE 273
Score = 58.0 bits (134), Expect = 6e-08
Identities = 56/229 (24%), Positives = 99/229 (43%), Gaps = 3/229 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPR-LRELYIQHTP 177
S+ L LS ++ +R+ F H ++ L L + + AF GL R L L +
Sbjct: 140 SLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNR 199
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
+ + AF L +T + L NRI IE F G N + ++ L+ N I ++ AF GL
Sbjct: 200 ITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGL 258
Query: 238 NDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESD 296
+ + + L + + + + GL + L L+ + + + ++ L L ++
Sbjct: 259 SKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNN 318
Query: 297 LGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
L + S L + L + +N I I E + S+RV L N +
Sbjct: 319 LTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEI 367
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 80.6 bits (190), Expect = 1e-14
Identities = 56/233 (24%), Positives = 117/233 (50%), Gaps = 4/233 (1%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P +TQL L+R +R++ F L L L L N++++ AF GL ++ L++++
Sbjct: 211 PRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNS 270
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
L V+S + L + + L++N IA+I ++ ++ + L N + R+ + + L
Sbjct: 271 LVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAEL 330
Query: 238 NDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT---FHGLIRVGRLSLR 293
+ + + L + I I AF GL + VL+L ++ + DT F GL + +L+L
Sbjct: 331 SSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLF 390
Query: 294 ESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHML 346
+ + + +F GL+ ++ L + N I ++ + V+ +++ ++ + L
Sbjct: 391 GNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFL 443
Score = 74.9 bits (176), Expect = 5e-13
Identities = 66/247 (26%), Positives = 111/247 (44%), Gaps = 5/247 (2%)
Query: 101 QVVCNSAALRGVPS--GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIR 158
+V N+ L VPS S V L L +R + L L L N+T +R
Sbjct: 96 EVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVR 155
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAAL-QNITSIVLTHNRIAQIESYAFAGTNFIN 217
F P ++EL + + T++ AF L +++ ++ L+ NRI Q+ AF
Sbjct: 156 NTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQ 215
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL 276
L L N I+ I F GLN + ++L + I + AF GL + VL L + L +
Sbjct: 216 L-DLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEV 274
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
+ +GL + +L L + + I + Q + L + N + ++E SL + +S+
Sbjct: 275 NSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLS 334
Query: 337 VFKLTGN 343
V +L+ N
Sbjct: 335 VLRLSHN 341
Score = 70.9 bits (166), Expect = 8e-12
Identities = 58/227 (25%), Positives = 111/227 (48%), Gaps = 4/227 (1%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHL-RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHT 176
P + +L+L+ + L AF L R L L L +T++ AF+ LPRL +L +
Sbjct: 163 PPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRN 221
Query: 177 PLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSG 236
+ ++ F L ++ + L N I+++ AF G + ++++ L N + + + G
Sbjct: 222 RIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYG 281
Query: 237 LNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRES 295
L + Q+ L + I I + ++ + + L L+F +L L ++ L + L L +
Sbjct: 282 LTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHN 341
Query: 296 DLGIIKVGSFDGLQHVDTLEICNNKIDG-IEELSLVQNNSVRVFKLT 341
+ I G+F GL+ + L++ +N+I G IE+ S + + KLT
Sbjct: 342 SISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLT 388
Score = 64.5 bits (150), Expect = 7e-10
Identities = 54/205 (26%), Positives = 94/205 (45%), Gaps = 4/205 (1%)
Query: 145 RRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQ 204
R L L L+ I P F LP L+E+Y+ + L V S AA ++ S+ L HN+I
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLG-AASSHVVSLFLQHNKIRS 129
Query: 205 IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL-EG 262
+E + ++ L N I + F + ++ L I T+E AF GL
Sbjct: 130 VEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRS 189
Query: 263 IGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
+ L L+ + + LP L R+ +L L + + +I+ +F GL ++ L++ N I
Sbjct: 190 LLTLRLS-KNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNIS 248
Query: 323 GIEELSLVQNNSVRVFKLTGNHMLE 347
+ + + + + V L N ++E
Sbjct: 249 KLTDGAFWGLSKMHVLHLEYNSLVE 273
Score = 58.0 bits (134), Expect = 6e-08
Identities = 56/229 (24%), Positives = 99/229 (43%), Gaps = 3/229 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPR-LRELYIQHTP 177
S+ L LS ++ +R+ F H ++ L L + + AF GL R L L +
Sbjct: 140 SLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNR 199
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
+ + AF L +T + L NRI IE F G N + ++ L+ N I ++ AF GL
Sbjct: 200 ITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGL 258
Query: 238 NDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESD 296
+ + + L + + + + GL + L L+ + + + ++ L L ++
Sbjct: 259 SKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNN 318
Query: 297 LGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
L + S L + L + +N I I E + S+RV L N +
Sbjct: 319 LTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEI 367
>AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein.
Length = 730
Score = 79.8 bits (188), Expect = 2e-14
Identities = 55/227 (24%), Positives = 108/227 (47%), Gaps = 2/227 (0%)
Query: 99 QSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIR 158
++++ C + L+ VP +S +VT LSL + + L F +L+++ L + I
Sbjct: 119 ETELECVNGDLKSVPM-ISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHIS 177
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINL 218
AF GL L+ LY+ H + T+ F L +T ++L N I +I F G N +
Sbjct: 178 RKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFF 237
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+S+ NN ++ + + + + ++L I+ + F + + VL+L+ + L
Sbjct: 238 LSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELS 297
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
P F L + +L+L + L + F+ L+ + +L++ +I I
Sbjct: 298 PHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNI 344
Score = 42.7 bits (96), Expect = 0.003
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 1/150 (0%)
Query: 213 TNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFM 271
+N + L+SL+ N I + F + +I L IR I +AF GL + +L L
Sbjct: 136 SNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHN 195
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+ +L P F L ++ L L ++ + I F GL + L + NN ++ + + Q
Sbjct: 196 CITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQ 255
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVENIII 361
+ L GN + + L +++ +
Sbjct: 256 MPQLNWVDLEGNRIKYLTNSTFLSCDSLTV 285
>AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein.
Length = 620
Score = 79.8 bits (188), Expect = 2e-14
Identities = 53/199 (26%), Positives = 93/199 (46%), Gaps = 2/199 (1%)
Query: 96 CLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q + V+C+ VP G+ L L + ++ L D FA L L L+ +
Sbjct: 48 CSAQDRAVLCHRKCFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIV 107
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + P AF L LR L ++ L + F L N+T ++ N+I + Y F
Sbjct: 108 SAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKQDISENKIVILLDYMFQDLY 167
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDL 273
+ + + +N + I AFSGLN + Q+ L + +I +A + L G+ VL L +++
Sbjct: 168 NLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNI 227
Query: 274 PSLLPDTFHGLIRVGRLSL 292
++ +F L R+ L +
Sbjct: 228 NAIRDYSFKRLYRLKVLEI 246
Score = 78.2 bits (184), Expect = 6e-14
Identities = 58/186 (31%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL+ S+ QL+L + +L + ++A +HL L L L N+ IR ++F+ L RL+ L I
Sbjct: 188 SGLN-SLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 246
Query: 174 QHTP-LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH 232
H P L T+ L N+TS+ +TH + + A ++ ++L NPI I
Sbjct: 247 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGS 305
Query: 233 AFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLS 291
L + +I+L G + +EP AF GL + VL ++ L +L FH + + L
Sbjct: 306 MLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 365
Query: 292 LRESDL 297
L + L
Sbjct: 366 LDSNPL 371
Score = 62.1 bits (144), Expect = 4e-09
Identities = 49/217 (22%), Positives = 98/217 (45%), Gaps = 2/217 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
GV +GLS ++T+ +S + +L F L L+ L + +L I AF GL L +
Sbjct: 137 GVFTGLS-NLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 195
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP-IKRI 229
L ++ L ++ + A + L + + L H I I Y+F + ++ + + P + +
Sbjct: 196 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTM 255
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
+ GLN + + A L + L L++ + ++ H L+R+
Sbjct: 256 TPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQE 315
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
+ L L +++ +F GL ++ L + N++ +EE
Sbjct: 316 IQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEE 352
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/81 (28%), Positives = 41/81 (50%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L+LS + + L +L+ + L L + P+AFRGL LR L + L T++
Sbjct: 292 LNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLE 351
Query: 183 SFAFAALQNITSIVLTHNRIA 203
F ++ N+ +++L N +A
Sbjct: 352 ESVFHSVGNLETLILDSNPLA 372
Score = 41.9 bits (94), Expect = 0.004
Identities = 38/158 (24%), Positives = 67/158 (42%), Gaps = 2/158 (1%)
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELPSGI-RTIEPQAFAGLEGIGVLELAFMDLPSL 276
L+ L N IK + F+ + ++EL I +EP AF L + L L L +
Sbjct: 75 LLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLI 134
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
F GL + + + E+ + I+ F L ++ +LE+ +N + I + NS+
Sbjct: 135 PLGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLE 194
Query: 337 VFKLTGNHMLESPEAVVLEVEN-IIIRGNHLPCECGRD 373
L ++ P + + I++R HL RD
Sbjct: 195 QLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRD 232
>Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 79.4 bits (187), Expect = 2e-14
Identities = 65/225 (28%), Positives = 102/225 (45%), Gaps = 3/225 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ A L VP+ L + L R LR L AF L LRRL+L NL+ I P A
Sbjct: 46 VRCDRAGLLRVPAELPCEAVSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGA 105
Query: 162 FRGLPRLRELYIQHT-PLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLIS 220
F+GLPRL EL + H L + + FAAL + + L R+ + A + ++
Sbjct: 106 FKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELA 165
Query: 221 LRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
+N +R+ A GL ++ L G I + + GL + L L + ++
Sbjct: 166 AFDNLFRRV-PGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAG 224
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
F + L L ++ L + +F GL+ + TL + N +D +
Sbjct: 225 AFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRV 269
Score = 48.4 bits (110), Expect = 5e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
A L L L+ + + + +GL RLR L +Q + V + AF + ++
Sbjct: 177 ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLL 236
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQ 255
L N +A++ + AF G + ++L N + R+ F+ L ++ + L + I +E
Sbjct: 237 LNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEG 296
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
AF L G+ L L L L F +GRL L
Sbjct: 297 AFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFL 333
Score = 48.0 bits (109), Expect = 7e-05
Identities = 32/96 (33%), Positives = 45/96 (46%)
Query: 130 LRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAAL 189
L L +DAF LR+LR L L L R+ F L L LY+ +A V+ AF L
Sbjct: 242 LAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNL 301
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ ++ L NR+ + AF F+ + L NP
Sbjct: 302 SGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNP 337
Score = 44.0 bits (99), Expect = 0.001
Identities = 35/112 (31%), Positives = 49/112 (43%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
LSL +R + + AF L L L+ L + AFRGL RLR L + L V
Sbjct: 211 LSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVA 270
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
FA L + + L N IA +E AF + + + L N + + AF
Sbjct: 271 RAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRLTVLAWVAF 322
>BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 79.4 bits (187), Expect = 2e-14
Identities = 65/225 (28%), Positives = 102/225 (45%), Gaps = 3/225 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ A L VP+ L + L R LR L AF L LRRL+L NL+ I P A
Sbjct: 46 VRCDRAGLLRVPAELPCEAVSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGA 105
Query: 162 FRGLPRLRELYIQHT-PLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLIS 220
F+GLPRL EL + H L + + FAAL + + L R+ + A + ++
Sbjct: 106 FKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELA 165
Query: 221 LRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
+N +R+ A GL ++ L G I + + GL + L L + ++
Sbjct: 166 AFDNLFRRV-PGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAG 224
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
F + L L ++ L + +F GL+ + TL + N +D +
Sbjct: 225 AFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRV 269
Score = 48.4 bits (110), Expect = 5e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
A L L L+ + + + +GL RLR L +Q + V + AF + ++
Sbjct: 177 ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLL 236
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQ 255
L N +A++ + AF G + ++L N + R+ F+ L ++ + L + I +E
Sbjct: 237 LNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEG 296
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
AF L G+ L L L L F +GRL L
Sbjct: 297 AFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFL 333
Score = 48.0 bits (109), Expect = 7e-05
Identities = 32/96 (33%), Positives = 45/96 (46%)
Query: 130 LRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAAL 189
L L +DAF LR+LR L L L R+ F L L LY+ +A V+ AF L
Sbjct: 242 LAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNL 301
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ ++ L NR+ + AF F+ + L NP
Sbjct: 302 SGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNP 337
Score = 44.0 bits (99), Expect = 0.001
Identities = 35/112 (31%), Positives = 49/112 (43%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
LSL +R + + AF L L L+ L + AFRGL RLR L + L V
Sbjct: 211 LSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVA 270
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
FA L + + L N IA +E AF + + + L N + + AF
Sbjct: 271 RAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRLTVLAWVAF 322
>AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat
protein protein.
Length = 481
Score = 79.4 bits (187), Expect = 2e-14
Identities = 65/225 (28%), Positives = 102/225 (45%), Gaps = 3/225 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ A L VP+ L + L R LR L AF L LRRL+L NL+ I P A
Sbjct: 46 VRCDRAGLLRVPAELPCEAVSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGA 105
Query: 162 FRGLPRLRELYIQHT-PLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLIS 220
F+GLPRL EL + H L + + FAAL + + L R+ + A + ++
Sbjct: 106 FKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELA 165
Query: 221 LRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
+N +R+ A GL ++ L G I + + GL + L L + ++
Sbjct: 166 AFDNLFRRV-PGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAG 224
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
F + L L ++ L + +F GL+ + TL + N +D +
Sbjct: 225 AFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRV 269
Score = 48.4 bits (110), Expect = 5e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
A L L L+ + + + +GL RLR L +Q + V + AF + ++
Sbjct: 177 ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLL 236
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQ 255
L N +A++ + AF G + ++L N + R+ F+ L ++ + L + I +E
Sbjct: 237 LNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEG 296
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
AF L G+ L L L L F +GRL L
Sbjct: 297 AFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFL 333
Score = 48.0 bits (109), Expect = 7e-05
Identities = 32/96 (33%), Positives = 45/96 (46%)
Query: 130 LRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAAL 189
L L +DAF LR+LR L L L R+ F L L LY+ +A V+ AF L
Sbjct: 242 LAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNL 301
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ ++ L NR+ + AF F+ + L NP
Sbjct: 302 SGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNP 337
Score = 44.0 bits (99), Expect = 0.001
Identities = 35/112 (31%), Positives = 49/112 (43%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
LSL +R + + AF L L L+ L + AFRGL RLR L + L V
Sbjct: 211 LSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVA 270
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
FA L + + L N IA +E AF + + + L N + + AF
Sbjct: 271 RAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRLTVLAWVAF 322
>AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 79.4 bits (187), Expect = 2e-14
Identities = 65/225 (28%), Positives = 102/225 (45%), Gaps = 3/225 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ A L VP+ L + L R LR L AF L LRRL+L NL+ I P A
Sbjct: 46 VRCDRAGLLRVPAELPCEAVSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGA 105
Query: 162 FRGLPRLRELYIQHT-PLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLIS 220
F+GLPRL EL + H L + + FAAL + + L R+ + A + ++
Sbjct: 106 FKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELA 165
Query: 221 LRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
+N +R+ A GL ++ L G I + + GL + L L + ++
Sbjct: 166 AFDNLFRRV-PGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAG 224
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
F + L L ++ L + +F GL+ + TL + N +D +
Sbjct: 225 AFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRV 269
Score = 48.4 bits (110), Expect = 5e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 1/157 (0%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
A L L L+ + + + +GL RLR L +Q + V + AF + ++
Sbjct: 177 ALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLL 236
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQ 255
L N +A++ + AF G + ++L N + R+ F+ L ++ + L + I +E
Sbjct: 237 LNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEG 296
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
AF L G+ L L L L F +GRL L
Sbjct: 297 AFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFL 333
Score = 48.0 bits (109), Expect = 7e-05
Identities = 32/96 (33%), Positives = 45/96 (46%)
Query: 130 LRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAAL 189
L L +DAF LR+LR L L L R+ F L L LY+ +A V+ AF L
Sbjct: 242 LAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNL 301
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ ++ L NR+ + AF F+ + L NP
Sbjct: 302 SGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNP 337
Score = 44.0 bits (99), Expect = 0.001
Identities = 35/112 (31%), Positives = 49/112 (43%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
LSL +R + + AF L L L+ L + AFRGL RLR L + L V
Sbjct: 211 LSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVA 270
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
FA L + + L N IA +E AF + + + L N + + AF
Sbjct: 271 RAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRLTVLAWVAF 322
>BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 79.0 bits (186), Expect = 3e-14
Identities = 73/315 (23%), Positives = 134/315 (42%), Gaps = 7/315 (2%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+S VP+ LSL + L D FA QL L LD ++ ++ AF+
Sbjct: 47 CDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQ 106
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
GL +L+EL + + + + F L N+ ++ L+ N+++ + F G + + LR+
Sbjct: 107 GLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRS 166
Query: 224 NPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFH 282
N ++ I V F + ++L + +R++ FAGL + L L L + F
Sbjct: 167 NSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFL 226
Query: 283 GLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTG 342
L + L L+ + + + G ++ L++ N+I I +L++ + L
Sbjct: 227 RLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAI-DLTVFETMPNLKILLMD 285
Query: 343 NHMLESPEAVVL----EVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPLKV 397
N+ L S ++ +L + + + GN C + L Q E + C SP
Sbjct: 286 NNKLNSLDSKILNSLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSILCHSPDHT 345
Query: 398 RGRSLASATSGSAGC 412
+G + A G C
Sbjct: 346 QGEDILDAVHGFQLC 360
>BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 79.0 bits (186), Expect = 3e-14
Identities = 73/315 (23%), Positives = 134/315 (42%), Gaps = 7/315 (2%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+S VP+ LSL + L D FA QL L LD ++ ++ AF+
Sbjct: 47 CDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQ 106
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
GL +L+EL + + + + F L N+ ++ L+ N+++ + F G + + LR+
Sbjct: 107 GLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRS 166
Query: 224 NPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFH 282
N ++ I V F + ++L + +R++ FAGL + L L L + F
Sbjct: 167 NSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFL 226
Query: 283 GLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTG 342
L + L L+ + + + G ++ L++ N+I I +L++ + L
Sbjct: 227 RLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAI-DLTVFETMPNLKILLMD 285
Query: 343 NHMLESPEAVVL----EVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPLKV 397
N+ L S ++ +L + + + GN C + L Q E + C SP
Sbjct: 286 NNKLNSLDSKILNSLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSILCHSPDHT 345
Query: 398 RGRSLASATSGSAGC 412
+G + A G C
Sbjct: 346 QGEDILDAVHGFQLC 360
>AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat
transmembrane neuronal 2 protein protein.
Length = 516
Score = 79.0 bits (186), Expect = 3e-14
Identities = 73/315 (23%), Positives = 134/315 (42%), Gaps = 7/315 (2%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+S VP+ LSL + L D FA QL L LD ++ ++ AF+
Sbjct: 47 CDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQ 106
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
GL +L+EL + + + + F L N+ ++ L+ N+++ + F G + + LR+
Sbjct: 107 GLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRS 166
Query: 224 NPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFH 282
N ++ I V F + ++L + +R++ FAGL + L L L + F
Sbjct: 167 NSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFL 226
Query: 283 GLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTG 342
L + L L+ + + + G ++ L++ N+I I +L++ + L
Sbjct: 227 RLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAI-DLTVFETMPNLKILLMD 285
Query: 343 NHMLESPEAVVL----EVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPLKV 397
N+ L S ++ +L + + + GN C + L Q E + C SP
Sbjct: 286 NNKLNSLDSKILNSLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSILCHSPDHT 345
Query: 398 RGRSLASATSGSAGC 412
+G + A G C
Sbjct: 346 QGEDILDAVHGFQLC 360
>AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein.
Length = 529
Score = 79.0 bits (186), Expect = 3e-14
Identities = 73/315 (23%), Positives = 134/315 (42%), Gaps = 7/315 (2%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+S VP+ LSL + L D FA QL L LD ++ ++ AF+
Sbjct: 60 CDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQ 119
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
GL +L+EL + + + + F L N+ ++ L+ N+++ + F G + + LR+
Sbjct: 120 GLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRS 179
Query: 224 NPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFH 282
N ++ I V F + ++L + +R++ FAGL + L L L + F
Sbjct: 180 NSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFL 239
Query: 283 GLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTG 342
L + L L+ + + + G ++ L++ N+I I +L++ + L
Sbjct: 240 RLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAI-DLTVFETMPNLKILLMD 298
Query: 343 NHMLESPEAVVL----EVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN-YCISPLKV 397
N+ L S ++ +L + + + GN C + L Q E + C SP
Sbjct: 299 NNKLNSLDSKILNSLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSILCHSPDHT 358
Query: 398 RGRSLASATSGSAGC 412
+G + A G C
Sbjct: 359 QGEDILDAVHGFQLC 373
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 78.6 bits (185), Expect = 4e-14
Identities = 72/275 (26%), Positives = 127/275 (46%), Gaps = 8/275 (2%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+G +GL S+ L L LR + ++A +LR L+ L LDA +++ + P F GL LR
Sbjct: 107 KGAFTGLY-SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLR 165
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI 229
L++ L + AF +L + ++ L N+I I YAF + + ++ L NN I +
Sbjct: 166 HLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSL 225
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLL--PDTFHGLIRV 287
F GL+ + ++L P A L + EL F D P F L +
Sbjct: 226 GKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNL--KELHFYDNPIQFVGRSAFQHLPEL 283
Query: 288 GRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLE 347
L+L + I + G ++++L + +I + + Q +++V L+ N + +
Sbjct: 284 RTLTLNGAS-QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLED 342
Query: 348 SPE-AVVLEVENIIIRGNHLPCECGRDPFTNPLAL 381
P +V +++ I +R N + E D F L+L
Sbjct: 343 LPSFSVCQKLQKIDLRHNEI-YEIKVDTFQQLLSL 376
Score = 58.4 bits (135), Expect = 5e-08
Identities = 57/231 (24%), Positives = 101/231 (43%), Gaps = 8/231 (3%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L + L F L L L L+ NL P A R L L+EL+ P+
Sbjct: 211 SLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLSNLKELHFYDNPI 269
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGL 237
V AF L + ++ L N +QI + GT + ++L I + + L
Sbjct: 270 QFVGRSAFQHLPELRTLTL--NGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQL 327
Query: 238 NDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ ++L + P +F+ + + ++L ++ + DTF L+ + L+L + +
Sbjct: 328 PNLQVLDLSYNLLEDLP-SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKI 386
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLES 348
II +F L + L++ +N + L + + KLTGNH L+S
Sbjct: 387 AIIHPNAFSTLPSLIKLDLSSNLLSSFPITGL---HGLTHLKLTGNHALQS 434
Score = 50.0 bits (114), Expect = 2e-05
Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 1/166 (0%)
Query: 188 ALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+L+ + + L N + I AF G + ++ L+NN ++ + A L + + L +
Sbjct: 88 SLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDA 147
Query: 248 G-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
I + P F+GL + L L L + F L + ++L + + I +F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV 352
L + L + NN+I + + +S+ L N++ E P A+
Sbjct: 208 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAI 253
Score = 41.5 bits (93), Expect = 0.006
Identities = 61/274 (22%), Positives = 116/274 (42%), Gaps = 24/274 (8%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL S+ L L L + AF L L+ + L + I +AF L L L++
Sbjct: 159 SGLH-SLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHL 217
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
+ + ++ F L ++ ++ L +N + + + A + + + +NPI+ + A
Sbjct: 218 HNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELHFYDNPIQFVGRSA 276
Query: 234 FSGL--------NDVGQI-ELP--SGIRTIEPQAFAGLEGIGVLELAFMDLPSL-LPDTF 281
F L N QI E P +G +E G + + + LP+L + D
Sbjct: 277 FQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLS 336
Query: 282 HGLI----------RVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+ L+ ++ ++ LR +++ IKV +F L + +L + NKI I +
Sbjct: 337 YNLLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFST 396
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVENIIIRGNH 365
S+ L+ N + P + + ++ + GNH
Sbjct: 397 LPSLIKLDLSSNLLSSFPITGLHGLTHLKLTGNH 430
Score = 36.7 bits (81), Expect = 0.17
Identities = 23/84 (27%), Positives = 41/84 (48%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L+ ++ LLP+ L + L L + L I G+F GL + L + NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 326 ELSLVQNNSVRVFKLTGNHMLESP 349
+L S++ +L NH+ P
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVP 154
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 78.6 bits (185), Expect = 4e-14
Identities = 72/275 (26%), Positives = 127/275 (46%), Gaps = 8/275 (2%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+G +GL S+ L L LR + ++A +LR L+ L LDA +++ + P F GL LR
Sbjct: 107 KGAFTGLY-SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLR 165
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI 229
L++ L + AF +L + ++ L N+I I YAF + + ++ L NN I +
Sbjct: 166 HLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSL 225
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLL--PDTFHGLIRV 287
F GL+ + ++L P A L + EL F D P F L +
Sbjct: 226 GKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNL--KELHFYDNPIQFVGRSAFQHLPEL 283
Query: 288 GRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLE 347
L+L + I + G ++++L + +I + + Q +++V L+ N + +
Sbjct: 284 RTLTLNGAS-QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLED 342
Query: 348 SPE-AVVLEVENIIIRGNHLPCECGRDPFTNPLAL 381
P +V +++ I +R N + E D F L+L
Sbjct: 343 LPSFSVCQKLQKIDLRHNEI-YEIKVDTFQQLLSL 376
Score = 58.4 bits (135), Expect = 5e-08
Identities = 57/231 (24%), Positives = 101/231 (43%), Gaps = 8/231 (3%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L + L F L L L L+ NL P A R L L+EL+ P+
Sbjct: 211 SLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLSNLKELHFYDNPI 269
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGL 237
V AF L + ++ L N +QI + GT + ++L I + + L
Sbjct: 270 QFVGRSAFQHLPELRTLTL--NGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQL 327
Query: 238 NDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ ++L + P +F+ + + ++L ++ + DTF L+ + L+L + +
Sbjct: 328 PNLQVLDLSYNLLEDLP-SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKI 386
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLES 348
II +F L + L++ +N + L + + KLTGNH L+S
Sbjct: 387 AIIHPNAFSTLPSLIKLDLSSNLLSSFPITGL---HGLTHLKLTGNHALQS 434
Score = 50.0 bits (114), Expect = 2e-05
Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 1/166 (0%)
Query: 188 ALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+L+ + + L N + I AF G + ++ L+NN ++ + A L + + L +
Sbjct: 88 SLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDA 147
Query: 248 G-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
I + P F+GL + L L L + F L + ++L + + I +F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV 352
L + L + NN+I + + +S+ L N++ E P A+
Sbjct: 208 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAI 253
Score = 41.5 bits (93), Expect = 0.006
Identities = 61/274 (22%), Positives = 116/274 (42%), Gaps = 24/274 (8%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL S+ L L L + AF L L+ + L + I +AF L L L++
Sbjct: 159 SGLH-SLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHL 217
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
+ + ++ F L ++ ++ L +N + + + A + + + +NPI+ + A
Sbjct: 218 HNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELHFYDNPIQFVGRSA 276
Query: 234 FSGL--------NDVGQI-ELP--SGIRTIEPQAFAGLEGIGVLELAFMDLPSL-LPDTF 281
F L N QI E P +G +E G + + + LP+L + D
Sbjct: 277 FQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLS 336
Query: 282 HGLI----------RVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+ L+ ++ ++ LR +++ IKV +F L + +L + NKI I +
Sbjct: 337 YNLLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFST 396
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVENIIIRGNH 365
S+ L+ N + P + + ++ + GNH
Sbjct: 397 LPSLIKLDLSSNLLSSFPITGLHGLTHLKLTGNH 430
Score = 36.7 bits (81), Expect = 0.17
Identities = 23/84 (27%), Positives = 41/84 (48%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L+ ++ LLP+ L + L L + L I G+F GL + L + NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 326 ELSLVQNNSVRVFKLTGNHMLESP 349
+L S++ +L NH+ P
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVP 154
>BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein.
Length = 522
Score = 78.6 bits (185), Expect = 4e-14
Identities = 58/233 (24%), Positives = 116/233 (49%), Gaps = 4/233 (1%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +++ C + L P LS + LSL L LR+ F L QL L LD +
Sbjct: 42 LCRCEGRLLYCEALNLTEAPHNLS-GLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNH 100
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ ++ AF+ L R++EL + + + + F + N+ S+ L++N++ + F G
Sbjct: 101 ICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGL 160
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMD 272
+ + +R N I+ + V F + +++ + ++++ +FAGL + L L D
Sbjct: 161 RKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHND 220
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L + F LI + L LR + + I+ V S D + +++ +++ N+I+ +E
Sbjct: 221 LVKVNFAHFPRLISLHSLCLRRNKVAIV-VSSLDWVWNLEKMDLSGNEIEYME 272
Score = 59.3 bits (137), Expect = 3e-08
Identities = 45/225 (20%), Positives = 106/225 (47%), Gaps = 2/225 (0%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
+T L L + ++ DAF LR+++ L L + +T++ FR +P LR + + + L
Sbjct: 91 LTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQ 150
Query: 180 TVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLND 239
+ F L+ +T++ + N I + F + + + N +K + ++F+GL
Sbjct: 151 ALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFK 210
Query: 240 VGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLG 298
+ ++ L + + + F L + L L + +++ + + + ++ L +++
Sbjct: 211 LTELHLEHNDLVKVNFAHFPRLISLHSLCLR-RNKVAIVVSSLDWVWNLEKMDLSGNEIE 269
Query: 299 IIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
++ F+ + H+ +L++ +N++ IE L S+ L GN
Sbjct: 270 YMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 33.1 bits (72), Expect = 2.1
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
L + H L + LSLR + L ++ G F GL + L + +N I ++ + + V+
Sbjct: 57 LTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVK 116
Query: 337 VFKLTGNHMLESPEAVVLEVENI 359
L+ N + + P + N+
Sbjct: 117 ELTLSSNQITQLPNTTFRPMPNL 139
>AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein.
Length = 522
Score = 78.6 bits (185), Expect = 4e-14
Identities = 58/233 (24%), Positives = 116/233 (49%), Gaps = 4/233 (1%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +++ C + L P LS + LSL L LR+ F L QL L LD +
Sbjct: 42 LCRCEGRLLYCEALNLTEAPHNLS-GLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNH 100
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ ++ AF+ L R++EL + + + + F + N+ S+ L++N++ + F G
Sbjct: 101 ICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGL 160
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMD 272
+ + +R N I+ + V F + +++ + ++++ +FAGL + L L D
Sbjct: 161 RKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHND 220
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L + F LI + L LR + + I+ V S D + +++ +++ N+I+ +E
Sbjct: 221 LVKVNFAHFPRLISLHSLCLRRNKVAIV-VSSLDWVWNLEKMDLSGNEIEYME 272
Score = 59.3 bits (137), Expect = 3e-08
Identities = 45/225 (20%), Positives = 106/225 (47%), Gaps = 2/225 (0%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
+T L L + ++ DAF LR+++ L L + +T++ FR +P LR + + + L
Sbjct: 91 LTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQ 150
Query: 180 TVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLND 239
+ F L+ +T++ + N I + F + + + N +K + ++F+GL
Sbjct: 151 ALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFK 210
Query: 240 VGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLG 298
+ ++ L + + + F L + L L + +++ + + + ++ L +++
Sbjct: 211 LTELHLEHNDLVKVNFAHFPRLISLHSLCLR-RNKVAIVVSSLDWVWNLEKMDLSGNEIE 269
Query: 299 IIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
++ F+ + H+ +L++ +N++ IE L S+ L GN
Sbjct: 270 YMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 33.1 bits (72), Expect = 2.1
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
L + H L + LSLR + L ++ G F GL + L + +N I ++ + + V+
Sbjct: 57 LTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVK 116
Query: 337 VFKLTGNHMLESPEAVVLEVENI 359
L+ N + + P + N+
Sbjct: 117 ELTLSSNQITQLPNTTFRPMPNL 139
>AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat
transmembrane neuronal 1 protein protein.
Length = 522
Score = 78.6 bits (185), Expect = 4e-14
Identities = 58/233 (24%), Positives = 116/233 (49%), Gaps = 4/233 (1%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +++ C + L P LS + LSL L LR+ F L QL L LD +
Sbjct: 42 LCRCEGRLLYCEALNLTEAPHNLS-GLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNH 100
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ ++ AF+ L R++EL + + + + F + N+ S+ L++N++ + F G
Sbjct: 101 ICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGL 160
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMD 272
+ + +R N I+ + V F + +++ + ++++ +FAGL + L L D
Sbjct: 161 RKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHND 220
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L + F LI + L LR + + I+ V S D + +++ +++ N+I+ +E
Sbjct: 221 LVKVNFAHFPRLISLHSLCLRRNKVAIV-VSSLDWVWNLEKMDLSGNEIEYME 272
Score = 59.3 bits (137), Expect = 3e-08
Identities = 45/225 (20%), Positives = 106/225 (47%), Gaps = 2/225 (0%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
+T L L + ++ DAF LR+++ L L + +T++ FR +P LR + + + L
Sbjct: 91 LTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQ 150
Query: 180 TVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLND 239
+ F L+ +T++ + N I + F + + + N +K + ++F+GL
Sbjct: 151 ALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFK 210
Query: 240 VGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLG 298
+ ++ L + + + F L + L L + +++ + + + ++ L +++
Sbjct: 211 LTELHLEHNDLVKVNFAHFPRLISLHSLCLR-RNKVAIVVSSLDWVWNLEKMDLSGNEIE 269
Query: 299 IIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
++ F+ + H+ +L++ +N++ IE L S+ L GN
Sbjct: 270 YMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 33.1 bits (72), Expect = 2.1
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
L + H L + LSLR + L ++ G F GL + L + +N I ++ + + V+
Sbjct: 57 LTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVK 116
Query: 337 VFKLTGNHMLESPEAVVLEVENI 359
L+ N + + P + N+
Sbjct: 117 ELTLSSNQITQLPNTTFRPMPNL 139
>AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens
cDNA FLJ32082 fis, clone OCBBF2000231, weakly similar to
PHOSPHOLIPASE A2 INHIBITOR SUBUNIT B PRECURSOR. ).
Length = 522
Score = 78.6 bits (185), Expect = 4e-14
Identities = 58/233 (24%), Positives = 116/233 (49%), Gaps = 4/233 (1%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +++ C + L P LS + LSL L LR+ F L QL L LD +
Sbjct: 42 LCRCEGRLLYCEALNLTEAPHNLS-GLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNH 100
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ ++ AF+ L R++EL + + + + F + N+ S+ L++N++ + F G
Sbjct: 101 ICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGL 160
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMD 272
+ + +R N I+ + V F + +++ + ++++ +FAGL + L L D
Sbjct: 161 RKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHND 220
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L + F LI + L LR + + I+ V S D + +++ +++ N+I+ +E
Sbjct: 221 LVKVNFAHFPRLISLHSLCLRRNKVAIV-VSSLDWVWNLEKMDLSGNEIEYME 272
Score = 59.3 bits (137), Expect = 3e-08
Identities = 45/225 (20%), Positives = 106/225 (47%), Gaps = 2/225 (0%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
+T L L + ++ DAF LR+++ L L + +T++ FR +P LR + + + L
Sbjct: 91 LTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQ 150
Query: 180 TVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLND 239
+ F L+ +T++ + N I + F + + + N +K + ++F+GL
Sbjct: 151 ALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFK 210
Query: 240 VGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLG 298
+ ++ L + + + F L + L L + +++ + + + ++ L +++
Sbjct: 211 LTELHLEHNDLVKVNFAHFPRLISLHSLCLR-RNKVAIVVSSLDWVWNLEKMDLSGNEIE 269
Query: 299 IIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
++ F+ + H+ +L++ +N++ IE L S+ L GN
Sbjct: 270 YMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 33.1 bits (72), Expect = 2.1
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
L + H L + LSLR + L ++ G F GL + L + +N I ++ + + V+
Sbjct: 57 LTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVK 116
Query: 337 VFKLTGNHMLESPEAVVLEVENI 359
L+ N + + P + N+
Sbjct: 117 ELTLSSNQITQLPNTTFRPMPNL 139
>AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 479
Score = 78.2 bits (184), Expect = 6e-14
Identities = 58/186 (31%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL+ S+ QL+L + +L + ++A +HL L L L N+ IR ++F+ L RL+ L I
Sbjct: 80 SGLN-SLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 138
Query: 174 QHTP-LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH 232
H P L T+ L N+TS+ +TH + + A ++ ++L NPI I
Sbjct: 139 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGS 197
Query: 233 AFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLS 291
L + +I+L G + +EP AF GL + VL ++ L +L FH + + L
Sbjct: 198 MLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 257
Query: 292 LRESDL 297
L + L
Sbjct: 258 LDSNPL 263
Score = 63.7 bits (148), Expect = 1e-09
Identities = 50/217 (23%), Positives = 99/217 (45%), Gaps = 2/217 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
GV +GLS ++T+L +S + +L F L L+ L + +L I AF GL L +
Sbjct: 29 GVFTGLS-NLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYIFHRAFSGLNSLEQ 87
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP-IKRI 229
L ++ L ++ + A + L + + L H I I Y+F + ++ + + P + +
Sbjct: 88 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTM 147
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
+ GLN + + A L + L L++ + ++ H L+R+
Sbjct: 148 TPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQE 207
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
+ L L +++ +F GL ++ L + N++ +EE
Sbjct: 208 IQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEE 244
Score = 58.8 bits (136), Expect = 4e-08
Identities = 37/137 (27%), Positives = 67/137 (48%), Gaps = 1/137 (0%)
Query: 157 IRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFI 216
+ P AF L LR L ++ L + F L N+T + ++ N+I + Y F +
Sbjct: 2 VEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNL 61
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPS 275
+ + +N + I AFSGLN + Q+ L + +I +A + L G+ VL L +++ +
Sbjct: 62 KSLEVGDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINA 121
Query: 276 LLPDTFHGLIRVGRLSL 292
+ +F L R+ L +
Sbjct: 122 IRDYSFKRLYRLKVLEI 138
Score = 56.8 bits (131), Expect = 1e-07
Identities = 68/263 (25%), Positives = 112/263 (42%), Gaps = 30/263 (11%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
AF +L LR L L + L I F GL L +L I + + + F L N+ S+
Sbjct: 6 AFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLE 65
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQ 255
+ N + I AF+G N + ++L + I A S L+ + + L I I
Sbjct: 66 VGDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDY 125
Query: 256 AFAGLEGIGVLELAFMD-LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTL 314
+F L + VLE++ L ++ P+ +GL + LS+ +L + + L ++ L
Sbjct: 126 SFKRLYRLKVLEISHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFL 184
Query: 315 EICNNKIDGIE-----------ELSLVQN-------------NSVRVFKLTGNHMLESPE 350
+ N I IE E+ LV N +RV ++GN + E
Sbjct: 185 NLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEE 244
Query: 351 AV---VLEVENIIIRGNHLPCEC 370
+V V +E +I+ N L C+C
Sbjct: 245 SVFHSVGNLETLILDSNPLACDC 267
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/81 (28%), Positives = 41/81 (50%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L+LS + + L +L+ + L L + P+AFRGL LR L + L T++
Sbjct: 184 LNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLE 243
Query: 183 SFAFAALQNITSIVLTHNRIA 203
F ++ N+ +++L N +A
Sbjct: 244 ESVFHSVGNLETLILDSNPLA 264
Score = 35.5 bits (78), Expect = 0.39
Identities = 17/44 (38%), Positives = 25/44 (56%)
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
P F+ L + L LR + L +I +G F GL ++ L+I NKI
Sbjct: 4 PGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKI 47
Score = 34.7 bits (76), Expect = 0.68
Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 1/123 (0%)
Query: 252 IEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHV 311
+EP AF L + L L L + F GL + +L + E+ + I+ F L ++
Sbjct: 2 VEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNL 61
Query: 312 DTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVEN-IIIRGNHLPCEC 370
+LE+ +N + I + NS+ L ++ P + + I++R HL
Sbjct: 62 KSLEVGDNDLVYIFHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINA 121
Query: 371 GRD 373
RD
Sbjct: 122 IRD 124
>AY324322-1|AAQ97217.1| 469|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 469
Score = 78.2 bits (184), Expect = 6e-14
Identities = 58/186 (31%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL+ S+ QL+L + +L + ++A +HL L L L N+ IR ++F+ L RL+ L I
Sbjct: 37 SGLN-SLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 95
Query: 174 QHTP-LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH 232
H P L T+ L N+TS+ +TH + + A ++ ++L NPI I
Sbjct: 96 SHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGS 154
Query: 233 AFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLS 291
L + +I+L G + +EP AF GL + VL ++ L +L FH + + L
Sbjct: 155 MLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 214
Query: 292 LRESDL 297
L + L
Sbjct: 215 LDSNPL 220
Score = 54.8 bits (126), Expect = 6e-07
Identities = 42/196 (21%), Positives = 85/196 (43%), Gaps = 1/196 (0%)
Query: 132 VLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQN 191
+L F L L+ L + +L I AF GL L +L ++ L ++ + A + L
Sbjct: 6 ILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHG 65
Query: 192 ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP-IKRILVHAFSGLNDVGQIELPSGIR 250
+ + L H I I Y+F + ++ + + P + + + GLN +
Sbjct: 66 LIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLT 125
Query: 251 TIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQH 310
+ A L + L L++ + ++ H L+R+ + L L +++ +F GL +
Sbjct: 126 AVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNY 185
Query: 311 VDTLEICNNKIDGIEE 326
+ L + N++ +EE
Sbjct: 186 LRVLNVSGNQLTTLEE 201
Score = 43.6 bits (98), Expect = 0.001
Identities = 23/81 (28%), Positives = 41/81 (50%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L+LS + + L +L+ + L L + P+AFRGL LR L + L T++
Sbjct: 141 LNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLE 200
Query: 183 SFAFAALQNITSIVLTHNRIA 203
F ++ N+ +++L N +A
Sbjct: 201 ESVFHSVGNLETLILDSNPLA 221
Score = 37.9 bits (84), Expect = 0.073
Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 200 NRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFA 258
N+I + Y F + + + +N + I AFSGLN + Q+ L + +I +A +
Sbjct: 2 NKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALS 61
Query: 259 GLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
L G+ VL L +++ ++ +F L R+ L +
Sbjct: 62 HLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI 95
>AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 967
Score = 77.4 bits (182), Expect = 1e-13
Identities = 67/230 (29%), Positives = 101/230 (43%), Gaps = 2/230 (0%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+ L VP L P L LS +L L+ F HLR L L L +L+ I AF
Sbjct: 52 CSELGLSAVPGDLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFS 111
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
GL L+ L +Q+ L + + A L ++ S+ L N I+ + +F G + + + L +
Sbjct: 112 GLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDD 171
Query: 224 NPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFH 282
N + I V A + L + + L + I I AF L + VL L + L +F
Sbjct: 172 NALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFE 231
Query: 283 GLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQN 332
GL + L L + L V + L + L NN I I E + + N
Sbjct: 232 GLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGN 280
Score = 45.6 bits (103), Expect = 4e-04
Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
LPRLR L + H + + S Q + I L HNRI +I + F+ + + + L N
Sbjct: 351 LPRLRVLELSHNQIEELPSLH--RCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 408
Query: 225 PIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
I+ I AFS L+ + +++L T P AGL G+ L+L
Sbjct: 409 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKL 450
Score = 41.1 bits (92), Expect = 0.008
Identities = 42/163 (25%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
AF +L +L L+L+ + P +G L L + + + S L + +
Sbjct: 300 AFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLE 358
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQ 255
L+HN+I ++ S + I L++N I I FS L+ + ++L + IR+I P+
Sbjct: 359 LSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPE 416
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV---GRLSLRES 295
AF+ L + L+L L +L GL+ + G L+L ++
Sbjct: 417 AFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQA 459
Score = 40.7 bits (91), Expect = 0.010
Identities = 38/151 (25%), Positives = 69/151 (45%), Gaps = 3/151 (1%)
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQ 255
L+ N + +++ F F+ + L N + I AFSGL + + L + + I +
Sbjct: 73 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 132
Query: 256 AFAGLEGIGVLELAFMDLPSLLPD-TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTL 314
A L + L L +L SL+P+ +F GL + L L ++ L I V + + L + +
Sbjct: 133 ALWELPSLQSLRLD-ANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 191
Query: 315 EICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ N+I I + + S+ V L N +
Sbjct: 192 TLALNRISHIPDYAFQNLTSLVVLHLHNNRI 222
Score = 40.3 bits (90), Expect = 0.014
Identities = 52/235 (22%), Positives = 94/235 (40%), Gaps = 4/235 (1%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P++ ++L+ + + AF +L L L L + + +F GL L L + +
Sbjct: 186 PALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK 245
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
L A L + + +N I I AF G + I +NPI+ + AF L
Sbjct: 246 LQEFP-VAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYL 304
Query: 238 NDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
+ + L + E G + +L L + L L R+ L L +
Sbjct: 305 PKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQ- 363
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLE-SPEA 351
I ++ S Q ++ + + +N+I I + Q +S++ L+ N + PEA
Sbjct: 364 -IEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEA 417
Score = 37.5 bits (83), Expect = 0.097
Identities = 26/85 (30%), Positives = 42/85 (49%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L+ +L L P FH L + L L + L I +F GL + L + NN++ GI
Sbjct: 71 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 130
Query: 326 ELSLVQNNSVRVFKLTGNHMLESPE 350
+L + S++ +L N + PE
Sbjct: 131 AEALWELPSLQSLRLDANLISLVPE 155
>AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein.
Length = 928
Score = 77.4 bits (182), Expect = 1e-13
Identities = 67/230 (29%), Positives = 101/230 (43%), Gaps = 2/230 (0%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+ L VP L P L LS +L L+ F HLR L L L +L+ I AF
Sbjct: 13 CSELGLSAVPGDLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFS 72
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
GL L+ L +Q+ L + + A L ++ S+ L N I+ + +F G + + + L +
Sbjct: 73 GLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDD 132
Query: 224 NPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFH 282
N + I V A + L + + L + I I AF L + VL L + L +F
Sbjct: 133 NALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFE 192
Query: 283 GLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQN 332
GL + L L + L V + L + L NN I I E + + N
Sbjct: 193 GLHNLETLDLNYNKLQEFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGN 241
Score = 45.6 bits (103), Expect = 4e-04
Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
LPRLR L + H + + S Q + I L HNRI +I + F+ + + + L N
Sbjct: 312 LPRLRVLELSHNQIEELPSLH--RCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 369
Query: 225 PIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
I+ I AFS L+ + +++L T P AGL G+ L+L
Sbjct: 370 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKL 411
Score = 41.1 bits (92), Expect = 0.008
Identities = 42/163 (25%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
AF +L +L L+L+ + P +G L L + + + S L + +
Sbjct: 261 AFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLE 319
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQ 255
L+HN+I ++ S + I L++N I I FS L+ + ++L + IR+I P+
Sbjct: 320 LSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPE 377
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV---GRLSLRES 295
AF+ L + L+L L +L GL+ + G L+L ++
Sbjct: 378 AFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQA 420
Score = 40.7 bits (91), Expect = 0.010
Identities = 38/151 (25%), Positives = 69/151 (45%), Gaps = 3/151 (1%)
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQ 255
L+ N + +++ F F+ + L N + I AFSGL + + L + + I +
Sbjct: 34 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 93
Query: 256 AFAGLEGIGVLELAFMDLPSLLPD-TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTL 314
A L + L L +L SL+P+ +F GL + L L ++ L I V + + L + +
Sbjct: 94 ALWELPSLQSLRLD-ANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 152
Query: 315 EICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ N+I I + + S+ V L N +
Sbjct: 153 TLALNRISHIPDYAFQNLTSLVVLHLHNNRI 183
Score = 40.3 bits (90), Expect = 0.014
Identities = 52/235 (22%), Positives = 94/235 (40%), Gaps = 4/235 (1%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P++ ++L+ + + AF +L L L L + + +F GL L L + +
Sbjct: 147 PALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK 206
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
L A L + + +N I I AF G + I +NPI+ + AF L
Sbjct: 207 LQEFP-VAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYL 265
Query: 238 NDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
+ + L + E G + +L L + L L R+ L L +
Sbjct: 266 PKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQ- 324
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLE-SPEA 351
I ++ S Q ++ + + +N+I I + Q +S++ L+ N + PEA
Sbjct: 325 -IEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEA 378
Score = 37.5 bits (83), Expect = 0.097
Identities = 26/85 (30%), Positives = 42/85 (49%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L+ +L L P FH L + L L + L I +F GL + L + NN++ GI
Sbjct: 32 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 91
Query: 326 ELSLVQNNSVRVFKLTGNHMLESPE 350
+L + S++ +L N + PE
Sbjct: 92 AEALWELPSLQSLRLDANLISLVPE 116
>BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like
family peptide receptor 1 protein.
Length = 757
Score = 77.0 bits (181), Expect = 1e-13
Identities = 61/233 (26%), Positives = 106/233 (45%), Gaps = 4/233 (1%)
Query: 96 CLSQS-QVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
CL Q ++ C+ LR VPS +S +VT +SL +R L D F + L++L L +
Sbjct: 104 CLCQGLELDCDETNLRAVPS-VSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKI 162
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T I +AFRGL L +LY+ H + + F L + +++ N +++I F G N
Sbjct: 163 TSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLN 222
Query: 215 FINLISLRNNPIKRILVHAF-SGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMD 272
+ L+ L NN + R+ + + ++L I + F + VL +
Sbjct: 223 SLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNK 282
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
+ L +TF L ++ L L + + + F L+ + L + N I I+
Sbjct: 283 INHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQ 335
Score = 39.5 bits (88), Expect = 0.024
Identities = 31/147 (21%), Positives = 63/147 (42%), Gaps = 1/147 (0%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
GL+ + + ++ R+ H+ +L L L+ ++ +R F L L ++
Sbjct: 220 GLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMR 279
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
+ ++ FA LQ + + L N+I + F ++ ++L NPI++I + F
Sbjct: 280 KNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQF 339
Query: 235 SGLNDVGQIELPS-GIRTIEPQAFAGL 260
L + + L I I+ + F L
Sbjct: 340 DYLVKLKSLSLEGIEISNIQQRMFRPL 366
>BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 77.0 bits (181), Expect = 1e-13
Identities = 61/233 (26%), Positives = 106/233 (45%), Gaps = 4/233 (1%)
Query: 96 CLSQS-QVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
CL Q ++ C+ LR VPS +S +VT +SL +R L D F + L++L L +
Sbjct: 104 CLCQGLELDCDETNLRAVPS-VSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKI 162
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T I +AFRGL L +LY+ H + + F L + +++ N +++I F G N
Sbjct: 163 TSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLN 222
Query: 215 FINLISLRNNPIKRILVHAF-SGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMD 272
+ L+ L NN + R+ + + ++L I + F + VL +
Sbjct: 223 SLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNK 282
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
+ L +TF L ++ L L + + + F L+ + L + N I I+
Sbjct: 283 INHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQ 335
Score = 39.5 bits (88), Expect = 0.024
Identities = 31/147 (21%), Positives = 63/147 (42%), Gaps = 1/147 (0%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
GL+ + + ++ R+ H+ +L L L+ ++ +R F L L ++
Sbjct: 220 GLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMR 279
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
+ ++ FA LQ + + L N+I + F ++ ++L NPI++I + F
Sbjct: 280 KNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQF 339
Query: 235 SGLNDVGQIELPS-GIRTIEPQAFAGL 260
L + + L I I+ + F L
Sbjct: 340 DYLVKLKSLSLEGIEISNIQQRMFRPL 366
>BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 77.0 bits (181), Expect = 1e-13
Identities = 62/250 (24%), Positives = 111/250 (44%), Gaps = 2/250 (0%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+G +GL S+ L L LR + ++A +LR L+ L LDA +++ + P F GL LR
Sbjct: 107 KGAFTGLY-SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLR 165
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI 229
L++ L + AF +L + ++ L N+I I YAF + + ++ L NN I +
Sbjct: 166 HLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSL 225
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GL+ + ++L P A L + L ++ S+ F G +
Sbjct: 226 GKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLIT 285
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
+ ++ + + +F L + TL + N E L ++ LTG + P
Sbjct: 286 IHFYDNPIQFVGRSAFQHLPELRTLTL-NGASQITEFPDLTGTANLESLTLTGAQISSLP 344
Query: 350 EAVVLEVENI 359
+ V ++ N+
Sbjct: 345 QTVCNQLPNL 354
Score = 53.6 bits (123), Expect = 1e-06
Identities = 50/213 (23%), Positives = 94/213 (44%), Gaps = 7/213 (3%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
A L L+ L + N+ I AF G P L ++ P+ V AF L + ++
Sbjct: 252 AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLT 311
Query: 197 LTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ 255
L N +QI + GT + ++L I + + L ++ ++L + P
Sbjct: 312 L--NGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP- 368
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLE 315
+F+ + + ++L ++ + DTF L+ + L+L + + II +F L + L+
Sbjct: 369 SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLD 428
Query: 316 ICNNKIDGIEELSLVQNNSVRVFKLTGNHMLES 348
+ +N + L + + KLTGNH L+S
Sbjct: 429 LSSNLLSSFPITGL---HGLTHLKLTGNHALQS 458
Score = 50.0 bits (114), Expect = 2e-05
Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 1/166 (0%)
Query: 188 ALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+L+ + + L N + I AF G + ++ L+NN ++ + A L + + L +
Sbjct: 88 SLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDA 147
Query: 248 G-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
I + P F+GL + L L L + F L + ++L + + I +F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV 352
L + L + NN+I + + +S+ L N++ E P A+
Sbjct: 208 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAI 253
Score = 45.2 bits (102), Expect = 5e-04
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 5/248 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L + L F L L L L+ NL P A R L L+EL +
Sbjct: 211 SLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLSNLKELGFHSNNI 269
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
++ AF ++ +I N I + AF + ++L N + +G
Sbjct: 270 RSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTL-NGASQITEFPDLTGTA 328
Query: 239 DVGQIELPSGIRTIEPQAFAG-LEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + L + PQ L + VL+L++ L L +F ++ ++ LR +++
Sbjct: 329 NLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL--PSFSVCQKLQKIDLRHNEI 386
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVE 357
IKV +F L + +L + NKI I + S+ L+ N + P + +
Sbjct: 387 YEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHGLT 446
Query: 358 NIIIRGNH 365
++ + GNH
Sbjct: 447 HLKLTGNH 454
Score = 39.5 bits (88), Expect = 0.024
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 5/151 (3%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + L+L+ A ++ L L L ++ + LP L+ L + +
Sbjct: 305 PELRTLTLNGAS-QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNL 363
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
L + SF+ Q + I L HN I +I+ F + ++L N I I +AFS L
Sbjct: 364 LEDLPSFSVC--QKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTL 421
Query: 238 NDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
+ +++L S + + P GL G+ L+L
Sbjct: 422 PSLIKLDLSSNLLSSFP--ITGLHGLTHLKL 450
Score = 36.7 bits (81), Expect = 0.17
Identities = 23/84 (27%), Positives = 41/84 (48%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L+ ++ LLP+ L + L L + L I G+F GL + L + NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 326 ELSLVQNNSVRVFKLTGNHMLESP 349
+L S++ +L NH+ P
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVP 154
>BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 77.0 bits (181), Expect = 1e-13
Identities = 62/250 (24%), Positives = 111/250 (44%), Gaps = 2/250 (0%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+G +GL S+ L L LR + ++A +LR L+ L LDA +++ + P F GL LR
Sbjct: 107 KGAFTGLY-SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLR 165
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI 229
L++ L + AF +L + ++ L N+I I YAF + + ++ L NN I +
Sbjct: 166 HLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSL 225
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GL+ + ++L P A L + L ++ S+ F G +
Sbjct: 226 GKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLIT 285
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
+ ++ + + +F L + TL + N E L ++ LTG + P
Sbjct: 286 IHFYDNPIQFVGRSAFQHLPELRTLTL-NGASQITEFPDLTGTANLESLTLTGAQISSLP 344
Query: 350 EAVVLEVENI 359
+ V ++ N+
Sbjct: 345 QTVCNQLPNL 354
Score = 53.6 bits (123), Expect = 1e-06
Identities = 50/213 (23%), Positives = 94/213 (44%), Gaps = 7/213 (3%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
A L L+ L + N+ I AF G P L ++ P+ V AF L + ++
Sbjct: 252 AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLT 311
Query: 197 LTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ 255
L N +QI + GT + ++L I + + L ++ ++L + P
Sbjct: 312 L--NGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP- 368
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLE 315
+F+ + + ++L ++ + DTF L+ + L+L + + II +F L + L+
Sbjct: 369 SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLD 428
Query: 316 ICNNKIDGIEELSLVQNNSVRVFKLTGNHMLES 348
+ +N + L + + KLTGNH L+S
Sbjct: 429 LSSNLLSSFPITGL---HGLTHLKLTGNHALQS 458
Score = 50.0 bits (114), Expect = 2e-05
Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 1/166 (0%)
Query: 188 ALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+L+ + + L N + I AF G + ++ L+NN ++ + A L + + L +
Sbjct: 88 SLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDA 147
Query: 248 G-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
I + P F+GL + L L L + F L + ++L + + I +F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV 352
L + L + NN+I + + +S+ L N++ E P A+
Sbjct: 208 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAI 253
Score = 45.2 bits (102), Expect = 5e-04
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 5/248 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L + L F L L L L+ NL P A R L L+EL +
Sbjct: 211 SLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLSNLKELGFHSNNI 269
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
++ AF ++ +I N I + AF + ++L N + +G
Sbjct: 270 RSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTL-NGASQITEFPDLTGTA 328
Query: 239 DVGQIELPSGIRTIEPQAFAG-LEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + L + PQ L + VL+L++ L L +F ++ ++ LR +++
Sbjct: 329 NLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL--PSFSVCQKLQKIDLRHNEI 386
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVE 357
IKV +F L + +L + NKI I + S+ L+ N + P + +
Sbjct: 387 YEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHGLT 446
Query: 358 NIIIRGNH 365
++ + GNH
Sbjct: 447 HLKLTGNH 454
Score = 39.5 bits (88), Expect = 0.024
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 5/151 (3%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + L+L+ A ++ L L L ++ + LP L+ L + +
Sbjct: 305 PELRTLTLNGAS-QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNL 363
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
L + SF+ Q + I L HN I +I+ F + ++L N I I +AFS L
Sbjct: 364 LEDLPSFSVC--QKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTL 421
Query: 238 NDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
+ +++L S + + P GL G+ L+L
Sbjct: 422 PSLIKLDLSSNLLSSFP--ITGLHGLTHLKL 450
Score = 36.7 bits (81), Expect = 0.17
Identities = 23/84 (27%), Positives = 41/84 (48%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L+ ++ LLP+ L + L L + L I G+F GL + L + NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 326 ELSLVQNNSVRVFKLTGNHMLESP 349
+L S++ +L NH+ P
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVP 154
>AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein.
Length = 724
Score = 77.0 bits (181), Expect = 1e-13
Identities = 61/233 (26%), Positives = 106/233 (45%), Gaps = 4/233 (1%)
Query: 96 CLSQS-QVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
CL Q ++ C+ LR VPS +S +VT +SL +R L D F + L++L L +
Sbjct: 71 CLCQGLELDCDETNLRAVPS-VSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKI 129
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T I +AFRGL L +LY+ H + + F L + +++ N +++I F G N
Sbjct: 130 TSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLN 189
Query: 215 FINLISLRNNPIKRILVHAF-SGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMD 272
+ L+ L NN + R+ + + ++L I + F + VL +
Sbjct: 190 SLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNK 249
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
+ L +TF L ++ L L + + + F L+ + L + N I I+
Sbjct: 250 INHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQ 302
Score = 39.5 bits (88), Expect = 0.024
Identities = 31/147 (21%), Positives = 63/147 (42%), Gaps = 1/147 (0%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
GL+ + + ++ R+ H+ +L L L+ ++ +R F L L ++
Sbjct: 187 GLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMR 246
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
+ ++ FA LQ + + L N+I + F ++ ++L NPI++I + F
Sbjct: 247 KNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQF 306
Query: 235 SGLNDVGQIELPS-GIRTIEPQAFAGL 260
L + + L I I+ + F L
Sbjct: 307 DYLVKLKSLSLEGIEISNIQQRMFRPL 333
>AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 77.0 bits (181), Expect = 1e-13
Identities = 61/233 (26%), Positives = 106/233 (45%), Gaps = 4/233 (1%)
Query: 96 CLSQS-QVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
CL Q ++ C+ LR VPS +S +VT +SL +R L D F + L++L L +
Sbjct: 104 CLCQGLELDCDETNLRAVPS-VSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKI 162
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T I +AFRGL L +LY+ H + + F L + +++ N +++I F G N
Sbjct: 163 TSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLN 222
Query: 215 FINLISLRNNPIKRILVHAF-SGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMD 272
+ L+ L NN + R+ + + ++L I + F + VL +
Sbjct: 223 SLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNK 282
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
+ L +TF L ++ L L + + + F L+ + L + N I I+
Sbjct: 283 INHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQ 335
Score = 39.5 bits (88), Expect = 0.024
Identities = 31/147 (21%), Positives = 63/147 (42%), Gaps = 1/147 (0%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
GL+ + + ++ R+ H+ +L L L+ ++ +R F L L ++
Sbjct: 220 GLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMR 279
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
+ ++ FA LQ + + L N+I + F ++ ++L NPI++I + F
Sbjct: 280 KNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQF 339
Query: 235 SGLNDVGQIELPS-GIRTIEPQAFAGL 260
L + + L I I+ + F L
Sbjct: 340 DYLVKLKSLSLEGIEISNIQQRMFRPL 366
>AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-coupled
receptor HG38 protein.
Length = 907
Score = 77.0 bits (181), Expect = 1e-13
Identities = 62/250 (24%), Positives = 111/250 (44%), Gaps = 2/250 (0%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+G +GL S+ L L LR + ++A +LR L+ L LDA +++ + P F GL LR
Sbjct: 107 KGAFTGLY-SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLR 165
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI 229
L++ L + AF +L + ++ L N+I I YAF + + ++ L NN I +
Sbjct: 166 HLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSL 225
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GL+ + ++L P A L + L ++ S+ F G +
Sbjct: 226 GKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLIT 285
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
+ ++ + + +F L + TL + N E L ++ LTG + P
Sbjct: 286 IHFYDNPIQFVGRSAFQHLPELRTLTL-NGASQITEFPDLTGTANLESLTLTGAQISSLP 344
Query: 350 EAVVLEVENI 359
+ V ++ N+
Sbjct: 345 QTVCNQLPNL 354
Score = 53.6 bits (123), Expect = 1e-06
Identities = 50/213 (23%), Positives = 94/213 (44%), Gaps = 7/213 (3%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
A L L+ L + N+ I AF G P L ++ P+ V AF L + ++
Sbjct: 252 AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLT 311
Query: 197 LTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ 255
L N +QI + GT + ++L I + + L ++ ++L + P
Sbjct: 312 L--NGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP- 368
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLE 315
+F+ + + ++L ++ + DTF L+ + L+L + + II +F L + L+
Sbjct: 369 SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLD 428
Query: 316 ICNNKIDGIEELSLVQNNSVRVFKLTGNHMLES 348
+ +N + L + + KLTGNH L+S
Sbjct: 429 LSSNLLSSFPITGL---HGLTHLKLTGNHALQS 458
Score = 50.0 bits (114), Expect = 2e-05
Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 1/166 (0%)
Query: 188 ALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+L+ + + L N + I AF G + ++ L+NN ++ + A L + + L +
Sbjct: 88 SLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDA 147
Query: 248 G-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
I + P F+GL + L L L + F L + ++L + + I +F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV 352
L + L + NN+I + + +S+ L N++ E P A+
Sbjct: 208 NLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAI 253
Score = 45.2 bits (102), Expect = 5e-04
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 5/248 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L + L F L L L L+ NL P A R L L+EL +
Sbjct: 211 SLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLSNLKELGFHSNNI 269
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
++ AF ++ +I N I + AF + ++L N + +G
Sbjct: 270 RSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTL-NGASQITEFPDLTGTA 328
Query: 239 DVGQIELPSGIRTIEPQAFAG-LEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + L + PQ L + VL+L++ L L +F ++ ++ LR +++
Sbjct: 329 NLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL--PSFSVCQKLQKIDLRHNEI 386
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVE 357
IKV +F L + +L + NKI I + S+ L+ N + P + +
Sbjct: 387 YEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHGLT 446
Query: 358 NIIIRGNH 365
++ + GNH
Sbjct: 447 HLKLTGNH 454
Score = 39.5 bits (88), Expect = 0.024
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 5/151 (3%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + L+L+ A ++ L L L ++ + LP L+ L + +
Sbjct: 305 PELRTLTLNGAS-QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNL 363
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
L + SF+ Q + I L HN I +I+ F + ++L N I I +AFS L
Sbjct: 364 LEDLPSFSVC--QKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTL 421
Query: 238 NDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
+ +++L S + + P GL G+ L+L
Sbjct: 422 PSLIKLDLSSNLLSSFP--ITGLHGLTHLKL 450
Score = 36.7 bits (81), Expect = 0.17
Identities = 23/84 (27%), Positives = 41/84 (48%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L+ ++ LLP+ L + L L + L I G+F GL + L + NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 326 ELSLVQNNSVRVFKLTGNHMLESP 349
+L S++ +L NH+ P
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVP 154
>BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein.
Length = 778
Score = 75.4 bits (177), Expect = 4e-13
Identities = 75/322 (23%), Positives = 127/322 (39%), Gaps = 7/322 (2%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S+ V C L VP + +L L L+V+ + AF + L L L C + +
Sbjct: 58 SRRHVACRYQNLTEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELV 117
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AFRGL RL L + L + A L ++ + L N + ++ F +
Sbjct: 118 AEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALA 177
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL 276
++L +N + + AF GL V + L + + + P+A AGL + L L +L +L
Sbjct: 178 TLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQAL 237
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEIC--NNKIDGIEELSLVQNNS 334
+ RL L + L G DGL E+ + + +
Sbjct: 238 PGPVLSQARGLARLELGHNPL--TYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPR 295
Query: 335 VRVFKLTGNHMLESPEAV-VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
+ L GN + P ++ + ++GN L C C P LA ++ + C
Sbjct: 296 LHTLDLRGNQLDTLPPLQGPGQLRRLRLQGNPLWCGCQARPLLEWLARAR-VRSDGACQG 354
Query: 394 PLKVRGRSLASATSGSAGCRGE 415
P ++RG +L + C G+
Sbjct: 355 PRRLRGEALDALRPWDLRCPGD 376
Score = 54.8 bits (126), Expect = 6e-07
Identities = 77/333 (23%), Positives = 120/333 (36%), Gaps = 22/333 (6%)
Query: 95 ICLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C+ +S+ C L+ VP G L L R + AF L L L L C
Sbjct: 417 VCVPESRHSSCEGCGLQAVPRGFRSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCG 476
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ + A GL RL LY+ LA + + A + + L NR Q+ A
Sbjct: 477 IAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRAL 536
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ--AFAGLEGIGVLELAFM 271
+ + L +N + R+ + + L SG R E A + L L
Sbjct: 537 PSLFSLHLHDNAVDRLAPGDLGRTRALRWVYL-SGNRITEVSLGALGPARELEKLHLDRN 595
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD----GLQHV----DTLE-ICNNKID 322
L + GL + L L + L ++ G+F LQH+ LE IC
Sbjct: 596 QLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFS 655
Query: 323 GIEELSLVQNNSVRVFKLTGNHMLESPEAVVL-EVENIIIRGNHLPCECGRDPFTNPLAL 381
G+ ++ L N + P L ++E I + N C+C P L
Sbjct: 656 GL-------GPGLQSLHLQKNQLRALPALPSLSQLELIDLSSNPFHCDCQLLPLHRWLT- 707
Query: 382 SQDFAEENYCISPLKVRGRSLASATSGSAGCRG 414
+ C +P RG+ + +A + C G
Sbjct: 708 GLNLRVGATCATPPNARGQRVKAAAAVFEDCPG 740
>BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product
protein.
Length = 811
Score = 75.4 bits (177), Expect = 4e-13
Identities = 63/256 (24%), Positives = 111/256 (43%), Gaps = 8/256 (3%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+L L L+ L A LR+LR L + ++R+ +F GL L +L + L +
Sbjct: 111 ELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGAL 170
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA--FSGLND 239
FA L N+ + L NRI + AFA + ++L N ++ L HA F+ L
Sbjct: 171 PDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRS 230
Query: 240 VGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLG 298
+ + L + ++ + P+ F L +G+L L L L P+ F GL + L L + L
Sbjct: 231 LSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLS 290
Query: 299 IIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVEN 358
+ + L ++ L++ N++ + + +R L N+ L + +
Sbjct: 291 QLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLR-NNALSALSGDIFAASP 349
Query: 359 IIIR----GNHLPCEC 370
+ R GN C+C
Sbjct: 350 ALYRLDLDGNGWTCDC 365
Score = 69.7 bits (163), Expect = 2e-11
Identities = 73/281 (25%), Positives = 122/281 (43%), Gaps = 10/281 (3%)
Query: 96 CLSQSQVVCNSAALRGVPSGLS-PS---VTQLSLSRADLRVLRSDAFAHLRQLRRLALDA 151
C ++C + LR VP S PS V SL + + + F L QLRRL L
Sbjct: 33 CQHPQHLLCTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQY 92
Query: 152 CNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFA 211
+ + P F L RL ELY+ + L + A L+ + + N I+++ +F
Sbjct: 93 NQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFE 152
Query: 212 GTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAF 270
G + + L N + + F+ L ++ + L S IR + AFA L + L L+
Sbjct: 153 GLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSA 212
Query: 271 MDL-PSLL-PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELS 328
+L PSL TF L + L L + L + F L + L + N++ + +
Sbjct: 213 NELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEA 272
Query: 329 LVQNNSVRVFKLTGNHMLESPEAV---VLEVENIIIRGNHL 366
++R +L GN + + P A+ + +E + + GN L
Sbjct: 273 FWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNEL 313
Score = 53.6 bits (123), Expect = 1e-06
Identities = 35/127 (27%), Positives = 63/127 (49%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S++ L LS L+ L F HL +L L+L LT + P AF GL LREL ++ L
Sbjct: 230 SLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRL 289
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ + + L ++ ++ L+ N ++ + F + +SLRNN + + F+
Sbjct: 290 SQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASP 349
Query: 239 DVGQIEL 245
+ +++L
Sbjct: 350 ALYRLDL 356
Score = 33.9 bits (74), Expect = 1.2
Identities = 26/107 (24%), Positives = 44/107 (41%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + LSL L L +AF L LR L L+ L+++ L L L +
Sbjct: 253 PRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNE 312
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
L+ + F L + + L +N ++ + FA + + + L N
Sbjct: 313 LSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGN 359
>AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA
sequence from clone RP4-756G23 on chromosome
22q13.31-13.33. ).
Length = 762
Score = 75.4 bits (177), Expect = 4e-13
Identities = 75/322 (23%), Positives = 127/322 (39%), Gaps = 7/322 (2%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S+ V C L VP + +L L L+V+ + AF + L L L C + +
Sbjct: 42 SRRHVACRYQNLTEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELV 101
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AFRGL RL L + L + A L ++ + L N + ++ F +
Sbjct: 102 AEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALA 161
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL 276
++L +N + + AF GL V + L + + + P+A AGL + L L +L +L
Sbjct: 162 TLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQAL 221
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEIC--NNKIDGIEELSLVQNNS 334
+ RL L + L G DGL E+ + + +
Sbjct: 222 PGPVLSQARGLARLELGHNPL--TYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPR 279
Query: 335 VRVFKLTGNHMLESPEAV-VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
+ L GN + P ++ + ++GN L C C P LA ++ + C
Sbjct: 280 LHTLDLRGNQLDTLPPLQGPGQLRRLRLQGNPLWCGCQARPLLEWLARAR-VRSDGACQG 338
Query: 394 PLKVRGRSLASATSGSAGCRGE 415
P ++RG +L + C G+
Sbjct: 339 PRRLRGEALDALRPWDLRCPGD 360
Score = 55.6 bits (128), Expect = 3e-07
Identities = 81/334 (24%), Positives = 125/334 (37%), Gaps = 24/334 (7%)
Query: 95 ICLSQSQ-VVCNSAALRGVPSGLSPSVTQL-SLSRADLRVLRSDAFAHLRQLRRLALDAC 152
+C+ +S+ C L+ VP G PS TQL L R + AF L L L L C
Sbjct: 401 VCVPESRHSSCEGCGLQAVPRGF-PSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHC 459
Query: 153 NLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAG 212
+ + A GL RL LY+ LA + + A + + L NR Q+ A
Sbjct: 460 GIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRA 519
Query: 213 TNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ--AFAGLEGIGVLELAF 270
+ + L++N + R+ + + L SG R E A + L L
Sbjct: 520 LPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYL-SGNRITEVSLGALGPARELEKLHLDR 578
Query: 271 MDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD----GLQHV----DTLE-ICNNKI 321
L + GL + L L + L ++ G+F LQH+ LE IC
Sbjct: 579 NQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAF 638
Query: 322 DGIEELSLVQNNSVRVFKLTGNHMLESPEAVVL-EVENIIIRGNHLPCECGRDPFTNPLA 380
G+ ++ L N + P L ++E I + N C+C P L
Sbjct: 639 SGL-------GPGLQSLHLQKNQLRALPALPSLSQLELIDLSSNPFHCDCQLLPLHRWLT 691
Query: 381 LSQDFAEENYCISPLKVRGRSLASATSGSAGCRG 414
+ C +P RG+ + +A + C G
Sbjct: 692 -GLNLRVGATCATPPNARGQRVKAAAAVFEDCPG 724
>AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein.
Length = 887
Score = 75.4 bits (177), Expect = 4e-13
Identities = 63/256 (24%), Positives = 111/256 (43%), Gaps = 8/256 (3%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+L L L+ L A LR+LR L + ++R+ +F GL L +L + L +
Sbjct: 187 ELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGAL 246
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA--FSGLND 239
FA L N+ + L NRI + AFA + ++L N ++ L HA F+ L
Sbjct: 247 PDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRS 306
Query: 240 VGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLG 298
+ + L + ++ + P+ F L +G+L L L L P+ F GL + L L + L
Sbjct: 307 LSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLS 366
Query: 299 IIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVEN 358
+ + L ++ L++ N++ + + +R L N+ L + +
Sbjct: 367 QLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLR-NNALSALSGDIFAASP 425
Query: 359 IIIR----GNHLPCEC 370
+ R GN C+C
Sbjct: 426 ALYRLDLDGNGWTCDC 441
Score = 69.7 bits (163), Expect = 2e-11
Identities = 73/281 (25%), Positives = 122/281 (43%), Gaps = 10/281 (3%)
Query: 96 CLSQSQVVCNSAALRGVPSGLS-PS---VTQLSLSRADLRVLRSDAFAHLRQLRRLALDA 151
C ++C + LR VP S PS V SL + + + F L QLRRL L
Sbjct: 109 CQHPQHLLCTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQY 168
Query: 152 CNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFA 211
+ + P F L RL ELY+ + L + A L+ + + N I+++ +F
Sbjct: 169 NQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFE 228
Query: 212 GTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAF 270
G + + L N + + F+ L ++ + L S IR + AFA L + L L+
Sbjct: 229 GLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSA 288
Query: 271 MDL-PSLL-PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELS 328
+L PSL TF L + L L + L + F L + L + N++ + +
Sbjct: 289 NELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEA 348
Query: 329 LVQNNSVRVFKLTGNHMLESPEAV---VLEVENIIIRGNHL 366
++R +L GN + + P A+ + +E + + GN L
Sbjct: 349 FWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNEL 389
Score = 53.6 bits (123), Expect = 1e-06
Identities = 35/127 (27%), Positives = 63/127 (49%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S++ L LS L+ L F HL +L L+L LT + P AF GL LREL ++ L
Sbjct: 306 SLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRL 365
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ + + L ++ ++ L+ N ++ + F + +SLRNN + + F+
Sbjct: 366 SQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSGDIFAASP 425
Query: 239 DVGQIEL 245
+ +++L
Sbjct: 426 ALYRLDL 432
Score = 33.9 bits (74), Expect = 1.2
Identities = 26/107 (24%), Positives = 44/107 (41%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + LSL L L +AF L LR L L+ L+++ L L L +
Sbjct: 329 PRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNE 388
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
L+ + F L + + L +N ++ + FA + + + L N
Sbjct: 389 LSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGN 435
>BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein.
Length = 1070
Score = 74.9 bits (176), Expect = 5e-13
Identities = 66/247 (26%), Positives = 111/247 (44%), Gaps = 5/247 (2%)
Query: 101 QVVCNSAALRGVPS--GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIR 158
+V N+ L VPS S V L L +R + L L L N+T +R
Sbjct: 96 EVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVR 155
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAAL-QNITSIVLTHNRIAQIESYAFAGTNFIN 217
F P ++EL + + T++ AF L +++ ++ L+ NRI Q+ AF
Sbjct: 156 NTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQ 215
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL 276
L L N I+ I F GLN + ++L + I + AF GL + VL L + L +
Sbjct: 216 L-DLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEV 274
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
+ +GL + +L L + + I + Q + L + N + ++E SL + +S+
Sbjct: 275 NSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLS 334
Query: 337 VFKLTGN 343
V +L+ N
Sbjct: 335 VLRLSHN 341
Score = 70.5 bits (165), Expect = 1e-11
Identities = 55/214 (25%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHL-RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHT 176
P + +L+L+ + L AF L R L L L +T++ AF+ LPRL +L +
Sbjct: 163 PPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRN 221
Query: 177 PLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSG 236
+ ++ F L ++ + L N I+++ AF G + ++++ L N + + + G
Sbjct: 222 RIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYG 281
Query: 237 LNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRES 295
L + Q+ L + I I + ++ + + L L+F +L L ++ L + L L +
Sbjct: 282 LTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHN 341
Query: 296 DLGIIKVGSFDGLQHVDTLEICNNKIDG-IEELS 328
+ I G+F GL+ + L++ +N+I G IE+ S
Sbjct: 342 SISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTS 375
Score = 62.9 bits (146), Expect = 2e-09
Identities = 53/205 (25%), Positives = 93/205 (45%), Gaps = 4/205 (1%)
Query: 145 RRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQ 204
R L L + I P F LP L+E+Y+ + L V S AA ++ S+ L HN+I
Sbjct: 71 RSLNLSYNKFSEIDPAGFEDLPNLQEVYLNNNELTAVPSLG-AASSHVVSLFLQHNKIRS 129
Query: 205 IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL-EG 262
+E + ++ L N I + F + ++ L I T+E AF GL
Sbjct: 130 VEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRS 189
Query: 263 IGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
+ L L+ + + LP L R+ +L L + + +I+ +F GL ++ L++ N I
Sbjct: 190 LLTLRLS-KNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNIS 248
Query: 323 GIEELSLVQNNSVRVFKLTGNHMLE 347
+ + + + + V L N ++E
Sbjct: 249 KLTDGAFWGLSKMHVLHLEYNSLVE 273
Score = 58.0 bits (134), Expect = 6e-08
Identities = 56/229 (24%), Positives = 99/229 (43%), Gaps = 3/229 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPR-LRELYIQHTP 177
S+ L LS ++ +R+ F H ++ L L + + AF GL R L L +
Sbjct: 140 SLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNR 199
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
+ + AF L +T + L NRI IE F G N + ++ L+ N I ++ AF GL
Sbjct: 200 ITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGL 258
Query: 238 NDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESD 296
+ + + L + + + + GL + L L+ + + + ++ L L ++
Sbjct: 259 SKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNN 318
Query: 297 LGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
L + S L + L + +N I I E + S+RV L N +
Sbjct: 319 LTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEI 367
Score = 50.4 bits (115), Expect = 1e-05
Identities = 49/186 (26%), Positives = 89/186 (47%), Gaps = 9/186 (4%)
Query: 100 SQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRP 159
S V NS +L G+ + + QL LS + + ++ ++L L L NLTR+
Sbjct: 270 SLVEVNSGSLYGLTA-----LHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDE 324
Query: 160 FAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA-QIE--SYAFAGTNFI 216
+ L L L + H ++ + AF L+++ + L HN I+ IE S AF+G + +
Sbjct: 325 ESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSL 384
Query: 217 N-LISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPS 275
+ L+ L + + ++ G+ + I+++ +AF+GLEG+ L L + S
Sbjct: 385 SKLLLLEPSQSAGCSSPSQPHMSAGGRTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRS 444
Query: 276 LLPDTF 281
+ D F
Sbjct: 445 VQFDAF 450
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 3/126 (2%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L L + S + L L +L L ++ RI + +L EL + L +D
Sbjct: 264 LHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLD 323
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH---AFSGLND 239
+ A L +++ + L+HN I+ I AF G + ++ L +N I + AFSGL+
Sbjct: 324 EESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDS 383
Query: 240 VGQIEL 245
+ ++ L
Sbjct: 384 LSKLLL 389
Score = 35.5 bits (78), Expect = 0.39
Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 3/132 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI---RPFAFRGLPRLRELYIQH 175
S++ L LS + + AF LR LR L LD ++ AF GL L +L +
Sbjct: 332 SLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLLLLE 391
Query: 176 TPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFS 235
+ S + L N+I + AF+G + ++L N I+ + AF
Sbjct: 392 PSQSAGCSSPSQPHMSAGGRTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFV 451
Query: 236 GLNDVGQIELPS 247
+ ++ ++ + S
Sbjct: 452 KMKNLKELHISS 463
>BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat
neuronal 1 protein.
Length = 716
Score = 74.9 bits (176), Expect = 5e-13
Identities = 73/282 (25%), Positives = 129/282 (45%), Gaps = 30/282 (10%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++T+L S+ + ++ A+L QL L L+ +T + + + L L+ELYI H +
Sbjct: 96 NLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQI 155
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+T+ + AFA L+N+ + L N++ I+S F T + ++ + NP+ IL F L
Sbjct: 156 STISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLA 215
Query: 239 DVGQI--------ELPS----GIRTIEPQAFAGLEGIGVLELAFMDLPSL----LPDTFH 282
++ + ++P G+ ++E +F + + V +LA +PSL L
Sbjct: 216 NLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPSLKFLDLNKNPI 275
Query: 283 GLIRVG--RLSLRESDLGIIKVG--------SFDGLQHVDTLEICNN-KIDGIEELSLVQ 331
I+ G + LR +LGI +G + D L + LE NN K+ I L+
Sbjct: 276 HKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRS 335
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVEN---IIIRGNHLPCEC 370
++ L N + + V + N I I N L C+C
Sbjct: 336 VPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLRCDC 377
Score = 65.7 bits (153), Expect = 3e-10
Identities = 61/247 (24%), Positives = 108/247 (43%), Gaps = 4/247 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V CN L +PS LS S TQ+ L +++ D L L L N T I+
Sbjct: 56 VDCNDLRLTRIPSNLS-SDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVG 114
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
L +L L+++ + + + L N+ + + HN+I+ I ++AFAG + + L
Sbjct: 115 LANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHL 174
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
+N +K I F ++ + + + + I F L + L LA M L + +
Sbjct: 175 NSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNA 234
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
GL + LS ++ L + + + + L++ N I I+E N +R+ +L
Sbjct: 235 LVGLDSLESLSFYDNKLVKVPQLALQKVPSLKFLDLNKNPIHKIQEGDF--KNMLRLKEL 292
Query: 341 TGNHMLE 347
N+M E
Sbjct: 293 GINNMGE 299
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 74.9 bits (176), Expect = 5e-13
Identities = 63/246 (25%), Positives = 108/246 (43%), Gaps = 4/246 (1%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C L +P L L+LS L + F L L+ + L L+ I P F
Sbjct: 54 CGGRGLAALPGDLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFE 113
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
LP L+E+Y+ + L V S AA ++ S+ L HN+I +E + ++ L
Sbjct: 114 DLPNLQEVYLNNNELTAVPSLG-AASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSL 172
Query: 224 NPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL-EGIGVLELAFMDLPSLLPDTF 281
N I + F + ++ L I T+E AF GL + L L+ + + LP
Sbjct: 173 NNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLS-KNRITQLPVRA 231
Query: 282 HGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLT 341
L R+ +L L + + +I+ +F GL ++ L++ N I + + + + + V L
Sbjct: 232 FKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLE 291
Query: 342 GNHMLE 347
N ++E
Sbjct: 292 YNSLVE 297
Score = 71.7 bits (168), Expect = 5e-12
Identities = 73/305 (23%), Positives = 140/305 (45%), Gaps = 12/305 (3%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHL-RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHT 176
P + +L+L+ + L AF L R L L L +T++ AF+ LPRL +L +
Sbjct: 187 PPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRN 245
Query: 177 PLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSG 236
+ ++ F L ++ + L N I+++ AF G + ++++ L N + + + G
Sbjct: 246 RIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYG 305
Query: 237 LNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRES 295
L + Q+ L + I I + ++ + + L L+F +L L ++ L + L L +
Sbjct: 306 LTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHN 365
Query: 296 DLGIIKVGSFDGLQHVDTLEICNNKIDG-IEELSLVQN--NSVRVFKLTGNHMLESPEAV 352
+ I G+F GL+ + L++ +N+I G IE+ S + +S+ L GN +
Sbjct: 366 SISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLNLGGNAIRSVQFDA 425
Query: 353 VLEVEN---IIIRGNHLPCECGRDPFTNPL--ALSQDFAEENYCISPLKVRGRSLASATS 407
++++N + I + C+C L + Q F C P ++G+S+ S
Sbjct: 426 FVKMKNLKELHISSDSFLCDCQLKWLPPWLIGRMLQAFVTAT-CAHPESLKGQSIFSVPP 484
Query: 408 GSAGC 412
S C
Sbjct: 485 ESFVC 489
>AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled receptor
LGR5 protein.
Length = 907
Score = 74.9 bits (176), Expect = 5e-13
Identities = 62/250 (24%), Positives = 110/250 (44%), Gaps = 2/250 (0%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+G +GL S+ L L LR + ++A +LR L+ L LDA +++ + P F GL LR
Sbjct: 107 KGAFTGLY-SLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLR 165
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI 229
L++ L + AF +L + ++ L N+I I YAF + ++ L NN I +
Sbjct: 166 HLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSL 225
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GL+ + ++L P A L + L ++ S+ F G +
Sbjct: 226 GKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLIT 285
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
+ ++ + + +F L + TL + N E L ++ LTG + P
Sbjct: 286 IHFYDNPIQFVGRSAFQHLPELRTLTL-NGASQITEFPDLTGTANLESLTLTGAQISSLP 344
Query: 350 EAVVLEVENI 359
+ V ++ N+
Sbjct: 345 QTVCNQLPNL 354
Score = 53.6 bits (123), Expect = 1e-06
Identities = 50/213 (23%), Positives = 94/213 (44%), Gaps = 7/213 (3%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
A L L+ L + N+ I AF G P L ++ P+ V AF L + ++
Sbjct: 252 AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLT 311
Query: 197 LTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ 255
L N +QI + GT + ++L I + + L ++ ++L + P
Sbjct: 312 L--NGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLP- 368
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLE 315
+F+ + + ++L ++ + DTF L+ + L+L + + II +F L + L+
Sbjct: 369 SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLD 428
Query: 316 ICNNKIDGIEELSLVQNNSVRVFKLTGNHMLES 348
+ +N + L + + KLTGNH L+S
Sbjct: 429 LSSNLLSSFPITGL---HGLTHLKLTGNHALQS 458
Score = 48.0 bits (109), Expect = 7e-05
Identities = 37/166 (22%), Positives = 70/166 (42%), Gaps = 1/166 (0%)
Query: 188 ALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+L + + L N + I AF G + ++ L+NN ++ + A L + + L +
Sbjct: 88 SLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDA 147
Query: 248 G-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
I + P F+GL + L L L + F L + ++L + + I +F
Sbjct: 148 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFG 207
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV 352
L L + NN+I + + +S+ L N++ E P A+
Sbjct: 208 NLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAI 253
Score = 44.0 bits (99), Expect = 0.001
Identities = 56/244 (22%), Positives = 100/244 (40%), Gaps = 5/244 (2%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + L F L L L L+ NL P A R L L+EL + ++
Sbjct: 215 LHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF-PTAIRTLSNLKELGFHSNNIRSIP 273
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF ++ +I N I + AF + ++L N + +G ++
Sbjct: 274 EKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTL-NGASQITEFPDLTGTANLES 332
Query: 243 IELPSGIRTIEPQAFAG-LEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIK 301
+ L + PQ L + VL+L++ L L +F ++ ++ LR +++ IK
Sbjct: 333 LTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL--PSFSVCQKLQKIDLRHNEIYEIK 390
Query: 302 VGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENIII 361
V +F L + +L + NKI I + S+ L+ N + P + + ++ +
Sbjct: 391 VDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 450
Query: 362 RGNH 365
GNH
Sbjct: 451 TGNH 454
Score = 39.5 bits (88), Expect = 0.024
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 5/151 (3%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + L+L+ A ++ L L L ++ + LP L+ L + +
Sbjct: 305 PELRTLTLNGAS-QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNL 363
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
L + SF+ Q + I L HN I +I+ F + ++L N I I +AFS L
Sbjct: 364 LEDLPSFSVC--QKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTL 421
Query: 238 NDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
+ +++L S + + P GL G+ L+L
Sbjct: 422 PSLIKLDLSSNLLSSFP--ITGLHGLTHLKL 450
Score = 36.7 bits (81), Expect = 0.17
Identities = 23/84 (27%), Positives = 41/84 (48%)
Query: 266 LELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
L+L+ ++ LLP+ L + L L + L I G+F GL + L + NN++ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 326 ELSLVQNNSVRVFKLTGNHMLESP 349
+L S++ +L NH+ P
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVP 154
>AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens
cDNA FLJ23995 fis, clone HRC11525. ).
Length = 459
Score = 74.5 bits (175), Expect = 7e-13
Identities = 54/185 (29%), Positives = 94/185 (50%), Gaps = 2/185 (1%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL S+ QL+L + +L + ++A +HLR L L L N+ + +AF+ L L+ L I
Sbjct: 27 SGLL-SLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEI 85
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
+ PL + N+TS+ +T+ ++ + AF ++ ++L NPI I
Sbjct: 86 DYWPLLDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGM 145
Query: 234 FSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
FS L + ++ + +RTIEP +F GL + VL ++ L +L + F + LS+
Sbjct: 146 FSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSI 205
Query: 293 RESDL 297
+ L
Sbjct: 206 NNNPL 210
Score = 62.5 bits (145), Expect = 3e-09
Identities = 50/207 (24%), Positives = 93/207 (44%), Gaps = 1/207 (0%)
Query: 138 FAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVL 197
F L L+ L + +L I AF GL L +L ++ L V + A + L+++ S+ L
Sbjct: 2 FQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHL 61
Query: 198 THNRIAQIESYAFAGTNFINLISLRNNPIKRIL-VHAFSGLNDVGQIELPSGIRTIEPQA 256
H I + YAF + + + P+ ++ ++ GLN + + T+ A
Sbjct: 62 KHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTNTNLSTVPFLA 121
Query: 257 FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEI 316
F L + L L++ + ++ F LIR+ L + + L I+ SF GL+ + L +
Sbjct: 122 FKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNV 181
Query: 317 CNNKIDGIEELSLVQNNSVRVFKLTGN 343
N ++ +EE ++ V + N
Sbjct: 182 SQNLLETLEENVFSSPRALEVLSINNN 208
Score = 57.2 bits (132), Expect = 1e-07
Identities = 49/205 (23%), Positives = 96/205 (46%), Gaps = 3/205 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L + DL + AF+ L L +L L+ CNLT + A L L L+++H +
Sbjct: 7 NLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNI 66
Query: 179 ATVDSFAFAALQNITSIVLTH-NRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
+ +AF L ++ + + + + + + + G N +L S+ N + + AF L
Sbjct: 67 NNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSL-SVTNTNLSTVPFLAFKHL 125
Query: 238 NDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESD 296
+ + L + I TIE F+ L + L + L ++ P +F GL + L++ ++
Sbjct: 126 VYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNL 185
Query: 297 LGIIKVGSFDGLQHVDTLEICNNKI 321
L ++ F + ++ L I NN +
Sbjct: 186 LETLEENVFSSPRALEVLSINNNPL 210
Score = 39.5 bits (88), Expect = 0.024
Identities = 22/84 (26%), Positives = 44/84 (52%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
+T L+LS + + + F+ L +L+ L + L I P +F+GL LR L + L
Sbjct: 128 LTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLE 187
Query: 180 TVDSFAFAALQNITSIVLTHNRIA 203
T++ F++ + + + + +N +A
Sbjct: 188 TLEENVFSSPRALEVLSINNNPLA 211
>BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein.
Length = 692
Score = 73.7 bits (173), Expect = 1e-12
Identities = 75/322 (23%), Positives = 126/322 (39%), Gaps = 7/322 (2%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S+ V C L VP + +L L L+V+ + AF + L L L C + +
Sbjct: 48 SRRHVACRYQNLTEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELV 107
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AFRGL RL L + L + A L ++ + L N + + F +
Sbjct: 108 AEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEGLRPGTFGALGALA 167
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL 276
++L +N + + AF GL V + L + + + P+A AGL + L L +L +L
Sbjct: 168 TLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQAL 227
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEIC--NNKIDGIEELSLVQNNS 334
+ RL L + L G DGL E+ + + +
Sbjct: 228 PGPVLSQARGLARLELGHNPL--TYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPR 285
Query: 335 VRVFKLTGNHMLESPEAV-VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
+ L GN + P ++ + ++GN L C C P LA ++ + C
Sbjct: 286 LHTLDLRGNQLDTLPPLQGPGQLRRLRLQGNPLWCGCQARPLLEWLARAR-VRSDGACQG 344
Query: 394 PLKVRGRSLASATSGSAGCRGE 415
P ++RG +L + C G+
Sbjct: 345 PRRLRGEALDALRPWDLRCPGD 366
Score = 54.0 bits (124), Expect = 1e-06
Identities = 51/220 (23%), Positives = 92/220 (41%), Gaps = 3/220 (1%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
+ L L + L + A A L +L + L L + A G PRL LY++
Sbjct: 457 LVSLHLQHCGIAELEAGALAGLGRLIYVYLSDNQLAGLSAAALEGAPRLGYLYLERNRFL 516
Query: 180 TVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLND 239
V A AL ++ S+ L N + ++ T + + L N I + + A +
Sbjct: 517 QVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARE 576
Query: 240 VGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIR-VGRLSLRESDL 297
+ ++ L + +R + A GL + L+L+ L +L F + R + L L S L
Sbjct: 577 LEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGL 636
Query: 298 GIIKVGSFDGL-QHVDTLEICNNKIDGIEELSLVQNNSVR 336
I G+F GL + +L + N++ + L + ++
Sbjct: 637 EQICPGAFSGLGPGLQSLHLQKNQLRALPALPSARRTPIK 676
Score = 40.7 bits (91), Expect = 0.010
Identities = 34/131 (25%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSL 276
L+ LR N + AF GL + + L GI +E A AGL + + L+ L L
Sbjct: 435 LLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYVYLSDNQLAGL 494
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
G R+G L L + + + L + +L + +N +D + L + ++R
Sbjct: 495 SAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALR 554
Query: 337 VFKLTGNHMLE 347
L+GN + E
Sbjct: 555 WVYLSGNRITE 565
>AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein.
Length = 709
Score = 73.7 bits (173), Expect = 1e-12
Identities = 44/135 (32%), Positives = 71/135 (52%), Gaps = 2/135 (1%)
Query: 96 CLSQS-QVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
CL Q ++ C+ LR VPS +S +VT +SL +R L D F + L++L L +
Sbjct: 104 CLCQGLELDCDETNLRAVPS-VSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKI 162
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T I +AFRGL L +LY+ H + + F L + +++ N +++I F G N
Sbjct: 163 TSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLN 222
Query: 215 FINLISLRNNPIKRI 229
+ L+ L NN + R+
Sbjct: 223 SLILLVLMNNVLTRL 237
Score = 59.3 bits (137), Expect = 3e-08
Identities = 39/175 (22%), Positives = 84/175 (48%), Gaps = 2/175 (1%)
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ ++ P F+ L++LY+Q+ + ++ +AF L ++T + L+HNRI ++ F
Sbjct: 138 IRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDL 197
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ--AFAGLEGIGVLELAFM 271
+ + + + +N + RI F GLN + + L + + T P + + L+L
Sbjct: 198 HRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN 257
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
+ +L TF + L +R++ + + +F LQ +D + +I I++
Sbjct: 258 HIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEFSLEGIEISNIQQ 312
Score = 48.0 bits (109), Expect = 7e-05
Identities = 48/199 (24%), Positives = 90/199 (45%), Gaps = 9/199 (4%)
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI 229
EL T L V S + N+T++ L N I ++ F + + + L+NN I I
Sbjct: 110 ELDCDETNLRAVPSVS----SNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSI 165
Query: 230 LVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVG 288
++AF GLN + ++ L + I ++P F L + L + L + P TF+GL +
Sbjct: 166 SIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLI 225
Query: 289 RLSLRESDLGIIKVGSF-DGLQHVDTLEICNNKIDGIEELSLVQNNSVRVF---KLTGNH 344
L L + L + + + L++ N I + L+ + +++ V K NH
Sbjct: 226 LLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINH 285
Query: 345 MLESPEAVVLEVENIIIRG 363
+ E+ A + +++ + G
Sbjct: 286 LNENTFAPLQKLDEFSLEG 304
Score = 33.5 bits (73), Expect = 1.6
Identities = 36/150 (24%), Positives = 60/150 (40%), Gaps = 25/150 (16%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL------------- 165
S+T+L LS + L+ F L +L L ++ +L+RI P F GL
Sbjct: 175 SLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVL 234
Query: 166 ------------PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
PRL L ++ + + + F + N+T +V+ N+I + FA
Sbjct: 235 TRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPL 294
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQI 243
++ SL I I F L ++ I
Sbjct: 295 QKLDEFSLEGIEISNIQQRMFRPLMNLSHI 324
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 73.7 bits (173), Expect = 1e-12
Identities = 53/195 (27%), Positives = 90/195 (46%), Gaps = 3/195 (1%)
Query: 106 SAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAH--LRQLRRLALDACNLTRIRPFAFR 163
++ L G P+ P+ S + D L A R RL LD N+TRI F
Sbjct: 23 ASVLSGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFA 82
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
GL LR L+++ ++ ++ AF L+ + + L N++ + F T + + L
Sbjct: 83 GLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSE 142
Query: 224 NPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFH 282
N I+ I AF G+ DV ++L + I IE AF L + +L L ++ +L +F+
Sbjct: 143 NQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFN 202
Query: 283 GLIRVGRLSLRESDL 297
+ ++ L L + L
Sbjct: 203 HMPKIRTLRLHSNHL 217
Score = 68.5 bits (160), Expect = 5e-11
Identities = 47/154 (30%), Positives = 76/154 (49%), Gaps = 2/154 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C + +V C++ L +PS L VT L L+ ++ VL + F L LR++ L
Sbjct: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ +R AF G ++EL + L TV F L + +++L N I+ + + FAG
Sbjct: 569 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLISCVSNDTFAGL 628
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+ + L+SL +N I I AF+ L + I L S
Sbjct: 629 SSVRLLSLYDNRITTITPGAFTTLVSLSTINLLS 662
Score = 65.3 bits (152), Expect = 4e-10
Identities = 43/143 (30%), Positives = 67/143 (46%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S + V C+ LR VP G+ + +L L R ++ + FA L+ LR L L+ ++ I
Sbjct: 41 SAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVI 100
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF+ L +L L + L + F + +T + L+ N+I I AF G +
Sbjct: 101 ERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVK 160
Query: 218 LISLRNNPIKRILVHAFSGLNDV 240
+ L NN I I AF L D+
Sbjct: 161 NLQLDNNHISCIEDGAFRALRDL 183
Score = 62.5 bits (145), Expect = 3e-09
Identities = 34/151 (22%), Positives = 71/151 (47%), Gaps = 1/151 (0%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C + +V C L +P+ L + ++ L + ++ + + AF ++L+R+ + +
Sbjct: 284 CTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQI 343
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ I P AF+GL L L + + + F L ++ ++L N+I + F
Sbjct: 344 SDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQ 403
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+NL+SL +N ++ I F+ L + + L
Sbjct: 404 NLNLLSLYDNKLQTISKGLFAPLQSIQTLHL 434
Score = 56.8 bits (131), Expect = 1e-07
Identities = 48/198 (24%), Positives = 87/198 (43%), Gaps = 4/198 (2%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI F+GL ++ + L + IE AF L+ + L L L L
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F ++ RL L E+ + I +F G+ V L++ NN I IE+ + + +
Sbjct: 126 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 185
Query: 338 FKLTGNHM---LESPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ L + + ++ + + NHL C+C ++ L + + C++P
Sbjct: 186 LTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAP 245
Query: 395 LKVRGRSLASATSGSAGC 412
+ +RG ++A C
Sbjct: 246 VHLRGFNVADVQKKEYVC 263
Score = 55.6 bits (128), Expect = 3e-07
Identities = 38/130 (29%), Positives = 63/130 (48%), Gaps = 2/130 (1%)
Query: 192 ITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
+T + L N ++ +E+ F + I+L NN IK + AF G V ++ L +
Sbjct: 534 VTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQL 593
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
T+ + F GL G+ L L + + DTF GL V LSL ++ + I G+F L
Sbjct: 594 ETVHGRVFRGLSGLKTLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLV 653
Query: 310 HVDTLEICNN 319
+ T+ + +N
Sbjct: 654 SLSTINLLSN 663
Score = 54.8 bits (126), Expect = 6e-07
Identities = 38/157 (24%), Positives = 68/157 (43%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L +N + I AF L + ++ L
Sbjct: 61 RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK 120
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + L+L+ + + F G+ V L L + + I+ G+F L
Sbjct: 121 LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRAL 180
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R +L NH+
Sbjct: 181 RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 52.4 bits (120), Expect = 3e-06
Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
I L N IK I AF+ + +I++ I I P AF GL+ + L L + +
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F GL+ + L L + + ++V +F LQ+++ L + +NK+ I + S++
Sbjct: 372 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQT 431
Query: 338 FKLTGN 343
L N
Sbjct: 432 LHLAQN 437
Score = 50.8 bits (116), Expect = 1e-05
Identities = 30/108 (27%), Positives = 54/108 (50%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P++ +++LS ++ +R AF ++ L L L + FRGL L+ L ++
Sbjct: 557 PNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNL 616
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
++ V + FA L ++ + L NRI I AF ++ I+L +NP
Sbjct: 617 ISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNP 664
Score = 50.8 bits (116), Expect = 1e-05
Identities = 32/108 (29%), Positives = 61/108 (56%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
RG+P+ + ELY++ L V +AL+++T I L++N I+ + +Y F+ + ++ + L
Sbjct: 748 RGMPKDVTELYLEGNHLTAVPR-ELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLIL 806
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
N ++ I VHAF+GL + + L + I ++ +F L + L L
Sbjct: 807 SYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLAL 854
Score = 49.2 bits (112), Expect = 3e-05
Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 2/132 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C VV C++ LR +P G+ VT+L L L + + A LR L + L ++
Sbjct: 729 CTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSA-LRHLTLIDLSNNSI 787
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + + F + L L + + L + AF L+++ + L N I+ + +F
Sbjct: 788 SMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLT 847
Query: 215 FINLISLRNNPI 226
++ ++L NP+
Sbjct: 848 SLSHLALGTNPL 859
Score = 47.6 bits (108), Expect = 9e-05
Identities = 28/108 (25%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Query: 186 FAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
F L N+ I L++N+I ++ AF G + + L N ++ + F GL+ + + L
Sbjct: 553 FKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLML 612
Query: 246 PSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
S I + FAGL + +L L + ++ P F L+ + ++L
Sbjct: 613 RSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINL 660
Score = 43.6 bits (98), Expect = 0.001
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 3/121 (2%)
Query: 108 ALRGVPSGLSPSVTQLS---LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRG 164
+++ +P+G +L +S+ + + DAF L+ L L L +T I F G
Sbjct: 318 SIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDG 377
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
L L+ L + + + F LQN+ + L N++ I FA I + L N
Sbjct: 378 LVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 437
Query: 225 P 225
P
Sbjct: 438 P 438
Score = 43.2 bits (97), Expect = 0.002
Identities = 21/104 (20%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
+ + L L+ +LT + P L L + + + ++ + ++ F+ + ++++++L++NR
Sbjct: 752 KDVTELYLEGNHLTAV-PRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 810
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ I +AF G + +++L N I + +F+ L + + L
Sbjct: 811 LRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLAL 854
Score = 42.3 bits (95), Expect = 0.003
Identities = 40/201 (19%), Positives = 84/201 (41%), Gaps = 5/201 (2%)
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSL 276
N++ R + I + G+ ++ ++E S I+ I AF + + ++++ + +
Sbjct: 289 NIVDCRGKGLMEIPANLPEGIVEI-RLEQNS-IKAIPAGAFTQYKKLKRIDISKNQISDI 346
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
PD F GL + L L + + I G FDGL + L + NKI+ + + ++
Sbjct: 347 APDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLN 406
Query: 337 VFKLTGNHMLESPE---AVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
+ L N + + A + ++ + + N C+C + L + C S
Sbjct: 407 LLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSS 466
Query: 394 PLKVRGRSLASATSGSAGCRG 414
P ++ + ++ S C G
Sbjct: 467 PRRLANKRISQIKSKKFRCSG 487
Score = 37.1 bits (82), Expect = 0.13
Identities = 64/272 (23%), Positives = 109/272 (40%), Gaps = 30/272 (11%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+T L L + + F L L+ L L+A + +R F+ L L L + L
Sbjct: 356 SLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKL 415
Query: 179 ATVDSFAFAALQNITSIVLTHNRIA------------QIESYAFAGTNFINLISLRNNPI 226
T+ FA LQ+I ++ L N Q +G + L N I
Sbjct: 416 QTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRI 475
Query: 227 KRILVHAF--SGLNDV-GQIELPSGIRTIEPQAFAGLEG--IGVLELAFMDLPSLLPDTF 281
+I F SG D + + + P+ EG + + +PS LP+
Sbjct: 476 SQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK-CRCEGTIVDCSNQKLVRIPSHLPEY- 533
Query: 282 HGLIRVGRLSLRESDLGIIKV-GSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
V L L ++++ +++ G F L ++ + + NNKI + E + SV+ L
Sbjct: 534 -----VTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELML 588
Query: 341 TGNHMLESPEAVVLE----VENIIIRGNHLPC 368
TGN LE+ V ++ +++R N + C
Sbjct: 589 TGN-QLETVHGRVFRGLSGLKTLMLRSNLISC 619
Score = 33.5 bits (73), Expect = 1.6
Identities = 33/153 (21%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
Query: 193 TSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI-LVHAFSGLNDVGQIELPSG-IR 250
T + ++ ++ +I S+ ++ + L +N + + F L ++ +I L + I+
Sbjct: 514 TIVDCSNQKLVRIPSHL---PEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIK 570
Query: 251 TIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQH 310
+ AF G + L L L ++ F GL + L LR + + + +F GL
Sbjct: 571 EVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLISCVSNDTFAGLSS 630
Query: 311 VDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
V L + +N+I I + S+ L N
Sbjct: 631 VRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 663
Score = 33.5 bits (73), Expect = 1.6
Identities = 28/141 (19%), Positives = 56/141 (39%), Gaps = 3/141 (2%)
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
+P L + + L + + ++ +F + H+ TL + N++ I + S+R
Sbjct: 767 VPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLR 826
Query: 337 VFKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
V L GN + PE + + ++ + N L C+C + + C S
Sbjct: 827 VLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSS 886
Query: 394 PLKVRGRSLASATSGSAGCRG 414
P + R L + + C+G
Sbjct: 887 PEPMADRLLLTTPTHRFQCKG 907
>AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein.
Length = 716
Score = 73.7 bits (173), Expect = 1e-12
Identities = 72/282 (25%), Positives = 129/282 (45%), Gaps = 30/282 (10%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++T+L S+ + ++ A+L QL L L+ +T + + + L L+ELYI H +
Sbjct: 96 NLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQI 155
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+T+ + AFA L+N+ + L N++ I+S F T + ++ + NP+ IL F L
Sbjct: 156 STISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLA 215
Query: 239 DVGQI--------ELPS----GIRTIEPQAFAGLEGIGVLELAFMDLPSL----LPDTFH 282
++ + ++P G+ ++E +F + + V +LA +P+L L
Sbjct: 216 NLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPI 275
Query: 283 GLIRVG--RLSLRESDLGIIKVG--------SFDGLQHVDTLEICNN-KIDGIEELSLVQ 331
I+ G + LR +LGI +G + D L + LE NN K+ I L+
Sbjct: 276 HKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRS 335
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVEN---IIIRGNHLPCEC 370
++ L N + + V + N I I N L C+C
Sbjct: 336 VPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLRCDC 377
Score = 66.5 bits (155), Expect = 2e-10
Identities = 61/247 (24%), Positives = 109/247 (44%), Gaps = 4/247 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V CN L +PS LS S TQ+ L +++ D L L L N T I+
Sbjct: 56 VDCNDLRLTRIPSNLS-SDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVG 114
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
L +L L+++ + + + L N+ + + HN+I+ I ++AFAG + + L
Sbjct: 115 LANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHL 174
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
+N +K I F ++ + + + + I F L + L LA M L + +
Sbjct: 175 NSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNA 234
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
GL + LS ++ L + + + ++ L++ N I I+E N +R+ +L
Sbjct: 235 LVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDF--KNMLRLKEL 292
Query: 341 TGNHMLE 347
N+M E
Sbjct: 293 GINNMGE 299
>AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein.
Length = 260
Score = 73.7 bits (173), Expect = 1e-12
Identities = 44/135 (32%), Positives = 71/135 (52%), Gaps = 2/135 (1%)
Query: 96 CLSQS-QVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
CL Q ++ C+ LR VPS +S +VT +SL +R L D F + L++L L +
Sbjct: 41 CLCQGLELDCDETNLRAVPS-VSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKI 99
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T I +AFRGL L +LY+ H + + F L + +++ N +++I F G N
Sbjct: 100 TSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLN 159
Query: 215 FINLISLRNNPIKRI 229
+ L+ L NN + R+
Sbjct: 160 SLILLVLMNNVLTRL 174
Score = 66.9 bits (156), Expect = 1e-10
Identities = 42/176 (23%), Positives = 88/176 (50%), Gaps = 2/176 (1%)
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ ++ P F+ L++LY+Q+ + ++ +AF L ++T + L+HNRI ++ F
Sbjct: 75 IRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDL 134
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ--AFAGLEGIGVLELAFM 271
+ + + + +N + RI F GLN + + L + + T P + + L+L
Sbjct: 135 HRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN 194
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEEL 327
+ +L TF + L +R++ + + +F LQ +D L++ +NKI+ + L
Sbjct: 195 HIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPL 250
Score = 48.0 bits (109), Expect = 7e-05
Identities = 48/202 (23%), Positives = 92/202 (45%), Gaps = 9/202 (4%)
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI 229
EL T L V S + N+T++ L N I ++ F + + + L+NN I I
Sbjct: 47 ELDCDETNLRAVPSVS----SNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSI 102
Query: 230 LVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVG 288
++AF GLN + ++ L + I ++P F L + L + L + P TF+GL +
Sbjct: 103 SIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLI 162
Query: 289 RLSLRESDLGIIKVGSF-DGLQHVDTLEICNNKIDGIEELSLVQNNSVRVF---KLTGNH 344
L L + L + + + L++ N I + L+ + +++ V K NH
Sbjct: 163 LLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINH 222
Query: 345 MLESPEAVVLEVENIIIRGNHL 366
+ E+ A + +++ + + N +
Sbjct: 223 LNENTFAPLQKLDELDLGSNKI 244
Score = 36.3 bits (80), Expect = 0.22
Identities = 35/149 (23%), Positives = 63/149 (42%), Gaps = 25/149 (16%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL------------- 165
S+T+L LS + L+ F L +L L ++ +L+RI P F GL
Sbjct: 112 SLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVL 171
Query: 166 ------------PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
PRL L ++ + + + F + N+T +V+ N+I + FA
Sbjct: 172 TRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPL 231
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQ 242
++ + L +N I+ + F L ++ Q
Sbjct: 232 QKLDELDLGSNKIENLPPLIFKDLKELSQ 260
>AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich
repeat protein-1 protein.
Length = 716
Score = 73.7 bits (173), Expect = 1e-12
Identities = 72/282 (25%), Positives = 129/282 (45%), Gaps = 30/282 (10%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++T+L S+ + ++ A+L QL L L+ +T + + + L L+ELYI H +
Sbjct: 96 NLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQI 155
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+T+ + AFA L+N+ + L N++ I+S F T + ++ + NP+ IL F L
Sbjct: 156 STISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLA 215
Query: 239 DVGQI--------ELPS----GIRTIEPQAFAGLEGIGVLELAFMDLPSL----LPDTFH 282
++ + ++P G+ ++E +F + + V +LA +P+L L
Sbjct: 216 NLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPI 275
Query: 283 GLIRVG--RLSLRESDLGIIKVG--------SFDGLQHVDTLEICNN-KIDGIEELSLVQ 331
I+ G + LR +LGI +G + D L + LE NN K+ I L+
Sbjct: 276 HKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRS 335
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVEN---IIIRGNHLPCEC 370
++ L N + + V + N I I N L C+C
Sbjct: 336 VPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLRCDC 377
Score = 66.5 bits (155), Expect = 2e-10
Identities = 61/247 (24%), Positives = 109/247 (44%), Gaps = 4/247 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V CN L +PS LS S TQ+ L +++ D L L L N T I+
Sbjct: 56 VDCNDLRLTRIPSNLS-SDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVG 114
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
L +L L+++ + + + L N+ + + HN+I+ I ++AFAG + + L
Sbjct: 115 LANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHL 174
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
+N +K I F ++ + + + + I F L + L LA M L + +
Sbjct: 175 NSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNA 234
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
GL + LS ++ L + + + ++ L++ N I I+E N +R+ +L
Sbjct: 235 LVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDF--KNMLRLKEL 292
Query: 341 TGNHMLE 347
N+M E
Sbjct: 293 GINNMGE 299
>AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein.
Length = 730
Score = 73.7 bits (173), Expect = 1e-12
Identities = 72/282 (25%), Positives = 129/282 (45%), Gaps = 30/282 (10%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++T+L S+ + ++ A+L QL L L+ +T + + + L L+ELYI H +
Sbjct: 110 NLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQI 169
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+T+ + AFA L+N+ + L N++ I+S F T + ++ + NP+ IL F L
Sbjct: 170 STISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLA 229
Query: 239 DVGQI--------ELPS----GIRTIEPQAFAGLEGIGVLELAFMDLPSL----LPDTFH 282
++ + ++P G+ ++E +F + + V +LA +P+L L
Sbjct: 230 NLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPI 289
Query: 283 GLIRVG--RLSLRESDLGIIKVG--------SFDGLQHVDTLEICNN-KIDGIEELSLVQ 331
I+ G + LR +LGI +G + D L + LE NN K+ I L+
Sbjct: 290 HKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRS 349
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVEN---IIIRGNHLPCEC 370
++ L N + + V + N I I N L C+C
Sbjct: 350 VPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLRCDC 391
Score = 66.5 bits (155), Expect = 2e-10
Identities = 61/247 (24%), Positives = 109/247 (44%), Gaps = 4/247 (1%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V CN L +PS LS S TQ+ L +++ D L L L N T I+
Sbjct: 70 VDCNDLRLTRIPSNLS-SDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVG 128
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
L +L L+++ + + + L N+ + + HN+I+ I ++AFAG + + L
Sbjct: 129 LANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHL 188
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
+N +K I F ++ + + + + I F L + L LA M L + +
Sbjct: 189 NSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNA 248
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
GL + LS ++ L + + + ++ L++ N I I+E N +R+ +L
Sbjct: 249 LVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDF--KNMLRLKEL 306
Query: 341 TGNHMLE 347
N+M E
Sbjct: 307 GINNMGE 313
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 73.7 bits (173), Expect = 1e-12
Identities = 53/195 (27%), Positives = 90/195 (46%), Gaps = 3/195 (1%)
Query: 106 SAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAH--LRQLRRLALDACNLTRIRPFAFR 163
++ L G P+ P+ S + D L A R RL LD N+TRI F
Sbjct: 23 ASVLSGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFA 82
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
GL LR L+++ ++ ++ AF L+ + + L N++ + F T + + L
Sbjct: 83 GLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSE 142
Query: 224 NPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFH 282
N I+ I AF G+ DV ++L + I IE AF L + +L L ++ +L +F+
Sbjct: 143 NQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFN 202
Query: 283 GLIRVGRLSLRESDL 297
+ ++ L L + L
Sbjct: 203 HMPKIRTLRLHSNHL 217
Score = 68.1 bits (159), Expect = 6e-11
Identities = 47/154 (30%), Positives = 75/154 (48%), Gaps = 2/154 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C + +V C++ L +PS L VT L L+ ++ VL + F L LR++ L
Sbjct: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ +R AF G ++EL + L TV F L + +++L N I + + FAG
Sbjct: 569 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGL 628
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+ + L+SL +N I I AF+ L + I L S
Sbjct: 629 SSVRLLSLYDNRITTITPGAFTTLVSLSTINLLS 662
Score = 65.3 bits (152), Expect = 4e-10
Identities = 43/143 (30%), Positives = 67/143 (46%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S + V C+ LR VP G+ + +L L R ++ + FA L+ LR L L+ ++ I
Sbjct: 41 SAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVI 100
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF+ L +L L + L + F + +T + L+ N+I I AF G +
Sbjct: 101 ERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVK 160
Query: 218 LISLRNNPIKRILVHAFSGLNDV 240
+ L NN I I AF L D+
Sbjct: 161 NLQLDNNHISCIEDGAFRALRDL 183
Score = 62.5 bits (145), Expect = 3e-09
Identities = 34/151 (22%), Positives = 71/151 (47%), Gaps = 1/151 (0%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C + +V C L +P+ L + ++ L + ++ + + AF ++L+R+ + +
Sbjct: 284 CTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQI 343
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ I P AF+GL L L + + + F L ++ ++L N+I + F
Sbjct: 344 SDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQ 403
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+NL+SL +N ++ I F+ L + + L
Sbjct: 404 NLNLLSLYDNKLQTISKGLFAPLQSIQTLHL 434
Score = 56.8 bits (131), Expect = 1e-07
Identities = 48/198 (24%), Positives = 87/198 (43%), Gaps = 4/198 (2%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI F+GL ++ + L + IE AF L+ + L L L L
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F ++ RL L E+ + I +F G+ V L++ NN I IE+ + + +
Sbjct: 126 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 185
Query: 338 FKLTGNHM---LESPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ L + + ++ + + NHL C+C ++ L + + C++P
Sbjct: 186 LTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAP 245
Query: 395 LKVRGRSLASATSGSAGC 412
+ +RG ++A C
Sbjct: 246 VHLRGFNVADVQKKEYVC 263
Score = 55.2 bits (127), Expect = 5e-07
Identities = 38/130 (29%), Positives = 63/130 (48%), Gaps = 2/130 (1%)
Query: 192 ITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
+T + L N ++ +E+ F + I+L NN IK + AF G V ++ L +
Sbjct: 534 VTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQL 593
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
T+ + F GL G+ L L + + DTF GL V LSL ++ + I G+F L
Sbjct: 594 ETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLV 653
Query: 310 HVDTLEICNN 319
+ T+ + +N
Sbjct: 654 SLSTINLLSN 663
Score = 54.8 bits (126), Expect = 6e-07
Identities = 38/157 (24%), Positives = 68/157 (43%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L +N + I AF L + ++ L
Sbjct: 61 RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK 120
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + L+L+ + + F G+ V L L + + I+ G+F L
Sbjct: 121 LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRAL 180
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R +L NH+
Sbjct: 181 RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 52.4 bits (120), Expect = 3e-06
Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
I L N IK I AF+ + +I++ I I P AF GL+ + L L + +
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F GL+ + L L + + ++V +F LQ+++ L + +NK+ I + S++
Sbjct: 372 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQT 431
Query: 338 FKLTGN 343
L N
Sbjct: 432 LHLAQN 437
Score = 50.8 bits (116), Expect = 1e-05
Identities = 32/108 (29%), Positives = 61/108 (56%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
RG+P+ + ELY++ L V +AL+++T I L++N I+ + +Y F+ + ++ + L
Sbjct: 748 RGMPKDVTELYLEGNHLTAVPR-ELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLIL 806
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
N ++ I VHAF+GL + + L + I ++ +F L + L L
Sbjct: 807 SYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLAL 854
Score = 50.4 bits (115), Expect = 1e-05
Identities = 30/108 (27%), Positives = 53/108 (49%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P++ +++LS ++ +R AF ++ L L L + FRGL L+ L ++
Sbjct: 557 PNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNL 616
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ V + FA L ++ + L NRI I AF ++ I+L +NP
Sbjct: 617 IGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNP 664
Score = 49.2 bits (112), Expect = 3e-05
Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 2/132 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C VV C++ LR +P G+ VT+L L L + + A LR L + L ++
Sbjct: 729 CTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSA-LRHLTLIDLSNNSI 787
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + + F + L L + + L + AF L+++ + L N I+ + +F
Sbjct: 788 SMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLT 847
Query: 215 FINLISLRNNPI 226
++ ++L NP+
Sbjct: 848 SLSHLALGTNPL 859
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/108 (25%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Query: 186 FAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
F L N+ I L++N+I ++ AF G + + L N ++ + F GL+ + + L
Sbjct: 553 FKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLML 612
Query: 246 PSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
S I + FAGL + +L L + ++ P F L+ + ++L
Sbjct: 613 RSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINL 660
Score = 43.6 bits (98), Expect = 0.001
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 3/121 (2%)
Query: 108 ALRGVPSGLSPSVTQLS---LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRG 164
+++ +P+G +L +S+ + + DAF L+ L L L +T I F G
Sbjct: 318 SIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDG 377
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
L L+ L + + + F LQN+ + L N++ I FA I + L N
Sbjct: 378 LVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 437
Query: 225 P 225
P
Sbjct: 438 P 438
Score = 43.2 bits (97), Expect = 0.002
Identities = 21/104 (20%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
+ + L L+ +LT + P L L + + + ++ + ++ F+ + ++++++L++NR
Sbjct: 752 KDVTELYLEGNHLTAV-PRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 810
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ I +AF G + +++L N I + +F+ L + + L
Sbjct: 811 LRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLAL 854
Score = 42.3 bits (95), Expect = 0.003
Identities = 40/201 (19%), Positives = 84/201 (41%), Gaps = 5/201 (2%)
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSL 276
N++ R + I + G+ ++ ++E S I+ I AF + + ++++ + +
Sbjct: 289 NIVDCRGKGLMEIPANLPEGIVEI-RLEQNS-IKAIPAGAFTQYKKLKRIDISKNQISDI 346
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
PD F GL + L L + + I G FDGL + L + NKI+ + + ++
Sbjct: 347 APDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLN 406
Query: 337 VFKLTGNHMLESPE---AVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
+ L N + + A + ++ + + N C+C + L + C S
Sbjct: 407 LLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSS 466
Query: 394 PLKVRGRSLASATSGSAGCRG 414
P ++ + ++ S C G
Sbjct: 467 PRRLANKRISQIKSKKFRCSG 487
Score = 35.9 bits (79), Expect = 0.30
Identities = 34/153 (22%), Positives = 66/153 (43%), Gaps = 5/153 (3%)
Query: 193 TSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI-LVHAFSGLNDVGQIELPSG-IR 250
T + ++ ++ +I S+ ++ + L +N + + F L ++ +I L + I+
Sbjct: 514 TIVDCSNQKLVRIPSHL---PEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIK 570
Query: 251 TIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQH 310
+ AF G + L L L ++ F GL + L LR + +G + +F GL
Sbjct: 571 EVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSS 630
Query: 311 VDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
V L + +N+I I + S+ L N
Sbjct: 631 VRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 663
Score = 33.5 bits (73), Expect = 1.6
Identities = 28/141 (19%), Positives = 56/141 (39%), Gaps = 3/141 (2%)
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
+P L + + L + + ++ +F + H+ TL + N++ I + S+R
Sbjct: 767 VPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLR 826
Query: 337 VFKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
V L GN + PE + + ++ + N L C+C + + C S
Sbjct: 827 VLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSS 886
Query: 394 PLKVRGRSLASATSGSAGCRG 414
P + R L + + C+G
Sbjct: 887 PEPMADRLLLTTPTHRFQCKG 907
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 73.7 bits (173), Expect = 1e-12
Identities = 53/195 (27%), Positives = 90/195 (46%), Gaps = 3/195 (1%)
Query: 106 SAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAH--LRQLRRLALDACNLTRIRPFAFR 163
++ L G P+ P+ S + D L A R RL LD N+TRI F
Sbjct: 59 ASVLSGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFA 118
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
GL LR L+++ ++ ++ AF L+ + + L N++ + F T + + L
Sbjct: 119 GLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSE 178
Query: 224 NPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFH 282
N I+ I AF G+ DV ++L + I IE AF L + +L L ++ +L +F+
Sbjct: 179 NQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFN 238
Query: 283 GLIRVGRLSLRESDL 297
+ ++ L L + L
Sbjct: 239 HMPKIRTLRLHSNHL 253
Score = 68.1 bits (159), Expect = 6e-11
Identities = 47/154 (30%), Positives = 75/154 (48%), Gaps = 2/154 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C + +V C++ L +PS L VT L L+ ++ VL + F L LR++ L
Sbjct: 545 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 604
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ +R AF G ++EL + L TV F L + +++L N I + + FAG
Sbjct: 605 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGL 664
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+ + L+SL +N I I AF+ L + I L S
Sbjct: 665 SSVRLLSLYDNRITTITPGAFTTLVSLSTINLLS 698
Score = 65.3 bits (152), Expect = 4e-10
Identities = 43/143 (30%), Positives = 67/143 (46%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S + V C+ LR VP G+ + +L L R ++ + FA L+ LR L L+ ++ I
Sbjct: 77 SAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVI 136
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF+ L +L L + L + F + +T + L+ N+I I AF G +
Sbjct: 137 ERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVK 196
Query: 218 LISLRNNPIKRILVHAFSGLNDV 240
+ L NN I I AF L D+
Sbjct: 197 NLQLDNNHISCIEDGAFRALRDL 219
Score = 62.5 bits (145), Expect = 3e-09
Identities = 34/151 (22%), Positives = 71/151 (47%), Gaps = 1/151 (0%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C + +V C L +P+ L + ++ L + ++ + + AF ++L+R+ + +
Sbjct: 320 CTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQI 379
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ I P AF+GL L L + + + F L ++ ++L N+I + F
Sbjct: 380 SDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQ 439
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+NL+SL +N ++ I F+ L + + L
Sbjct: 440 NLNLLSLYDNKLQTISKGLFAPLQSIQTLHL 470
Score = 56.8 bits (131), Expect = 1e-07
Identities = 48/198 (24%), Positives = 87/198 (43%), Gaps = 4/198 (2%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI F+GL ++ + L + IE AF L+ + L L L L
Sbjct: 102 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 161
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F ++ RL L E+ + I +F G+ V L++ NN I IE+ + + +
Sbjct: 162 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 221
Query: 338 FKLTGNHM---LESPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ L + + ++ + + NHL C+C ++ L + + C++P
Sbjct: 222 LTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAP 281
Query: 395 LKVRGRSLASATSGSAGC 412
+ +RG ++A C
Sbjct: 282 VHLRGFNVADVQKKEYVC 299
Score = 55.2 bits (127), Expect = 5e-07
Identities = 38/130 (29%), Positives = 63/130 (48%), Gaps = 2/130 (1%)
Query: 192 ITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
+T + L N ++ +E+ F + I+L NN IK + AF G V ++ L +
Sbjct: 570 VTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQL 629
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
T+ + F GL G+ L L + + DTF GL V LSL ++ + I G+F L
Sbjct: 630 ETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLV 689
Query: 310 HVDTLEICNN 319
+ T+ + +N
Sbjct: 690 SLSTINLLSN 699
Score = 54.8 bits (126), Expect = 6e-07
Identities = 38/157 (24%), Positives = 68/157 (43%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L +N + I AF L + ++ L
Sbjct: 97 RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK 156
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + L+L+ + + F G+ V L L + + I+ G+F L
Sbjct: 157 LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRAL 216
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R +L NH+
Sbjct: 217 RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 253
Score = 52.4 bits (120), Expect = 3e-06
Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
I L N IK I AF+ + +I++ I I P AF GL+ + L L + +
Sbjct: 348 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 407
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F GL+ + L L + + ++V +F LQ+++ L + +NK+ I + S++
Sbjct: 408 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQT 467
Query: 338 FKLTGN 343
L N
Sbjct: 468 LHLAQN 473
Score = 50.8 bits (116), Expect = 1e-05
Identities = 32/108 (29%), Positives = 61/108 (56%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
RG+P+ + ELY++ L V +AL+++T I L++N I+ + +Y F+ + ++ + L
Sbjct: 784 RGMPKDVTELYLEGNHLTAVPR-ELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLIL 842
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
N ++ I VHAF+GL + + L + I ++ +F L + L L
Sbjct: 843 SYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLAL 890
Score = 50.4 bits (115), Expect = 1e-05
Identities = 30/108 (27%), Positives = 53/108 (49%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P++ +++LS ++ +R AF ++ L L L + FRGL L+ L ++
Sbjct: 593 PNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNL 652
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ V + FA L ++ + L NRI I AF ++ I+L +NP
Sbjct: 653 IGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNP 700
Score = 49.2 bits (112), Expect = 3e-05
Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 2/132 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C VV C++ LR +P G+ VT+L L L + + A LR L + L ++
Sbjct: 765 CTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSA-LRHLTLIDLSNNSI 823
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + + F + L L + + L + AF L+++ + L N I+ + +F
Sbjct: 824 SMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLT 883
Query: 215 FINLISLRNNPI 226
++ ++L NP+
Sbjct: 884 SLSHLALGTNPL 895
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/108 (25%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Query: 186 FAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
F L N+ I L++N+I ++ AF G + + L N ++ + F GL+ + + L
Sbjct: 589 FKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLML 648
Query: 246 PSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
S I + FAGL + +L L + ++ P F L+ + ++L
Sbjct: 649 RSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINL 696
Score = 43.6 bits (98), Expect = 0.001
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 3/121 (2%)
Query: 108 ALRGVPSGLSPSVTQLS---LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRG 164
+++ +P+G +L +S+ + + DAF L+ L L L +T I F G
Sbjct: 354 SIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDG 413
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
L L+ L + + + F LQN+ + L N++ I FA I + L N
Sbjct: 414 LVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 473
Query: 225 P 225
P
Sbjct: 474 P 474
Score = 43.2 bits (97), Expect = 0.002
Identities = 21/104 (20%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
+ + L L+ +LT + P L L + + + ++ + ++ F+ + ++++++L++NR
Sbjct: 788 KDVTELYLEGNHLTAV-PRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 846
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ I +AF G + +++L N I + +F+ L + + L
Sbjct: 847 LRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLAL 890
Score = 42.3 bits (95), Expect = 0.003
Identities = 40/201 (19%), Positives = 84/201 (41%), Gaps = 5/201 (2%)
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSL 276
N++ R + I + G+ ++ ++E S I+ I AF + + ++++ + +
Sbjct: 325 NIVDCRGKGLMEIPANLPEGIVEI-RLEQNS-IKAIPAGAFTQYKKLKRIDISKNQISDI 382
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
PD F GL + L L + + I G FDGL + L + NKI+ + + ++
Sbjct: 383 APDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLN 442
Query: 337 VFKLTGNHMLESPE---AVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
+ L N + + A + ++ + + N C+C + L + C S
Sbjct: 443 LLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSS 502
Query: 394 PLKVRGRSLASATSGSAGCRG 414
P ++ + ++ S C G
Sbjct: 503 PRRLANKRISQIKSKKFRCSG 523
Score = 35.9 bits (79), Expect = 0.30
Identities = 34/153 (22%), Positives = 66/153 (43%), Gaps = 5/153 (3%)
Query: 193 TSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI-LVHAFSGLNDVGQIELPSG-IR 250
T + ++ ++ +I S+ ++ + L +N + + F L ++ +I L + I+
Sbjct: 550 TIVDCSNQKLVRIPSHL---PEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIK 606
Query: 251 TIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQH 310
+ AF G + L L L ++ F GL + L LR + +G + +F GL
Sbjct: 607 EVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSS 666
Query: 311 VDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
V L + +N+I I + S+ L N
Sbjct: 667 VRLLSLYDNRITTITPGAFTTLVSLSTINLLSN 699
Score = 33.5 bits (73), Expect = 1.6
Identities = 28/141 (19%), Positives = 56/141 (39%), Gaps = 3/141 (2%)
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
+P L + + L + + ++ +F + H+ TL + N++ I + S+R
Sbjct: 803 VPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLR 862
Query: 337 VFKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
V L GN + PE + + ++ + N L C+C + + C S
Sbjct: 863 VLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSS 922
Query: 394 PLKVRGRSLASATSGSAGCRG 414
P + R L + + C+G
Sbjct: 923 PEPMADRLLLTTPTHRFQCKG 943
>BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 73.3 bits (172), Expect = 2e-12
Identities = 65/258 (25%), Positives = 113/258 (43%), Gaps = 6/258 (2%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
G ++T+L LS+ R F L QL L L+ LTR+ +F GL L+ELY+
Sbjct: 90 GYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLN 149
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
H L + AF+ L N+ + L N + I+S F + ++ + N + IL F
Sbjct: 150 HNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNF 209
Query: 235 SGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLR 293
L ++ + L +R I A GL+ + L L + + + L L
Sbjct: 210 RPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLN 269
Query: 294 ESDLGIIKVGSFDGLQHVDTLEICN-NKIDGIEELSLVQNNSVRVFKLTGNHMLE--SPE 350
++ L + G F + H+ L + N ++ I++ +LV + +T N L P
Sbjct: 270 KNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPR 329
Query: 351 AV--VLEVENIIIRGNHL 366
A + ++E +++ N L
Sbjct: 330 AFHHLPQMETLMLNNNAL 347
Score = 64.5 bits (150), Expect = 7e-10
Identities = 58/227 (25%), Positives = 106/227 (46%), Gaps = 7/227 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSL--SRADLRVLRSDAFAHLRQLRRLALDACNLTRIRP 159
V CN L VP L P+ TQ L S + +RV +S+ +L L L L + + R
Sbjct: 53 VDCNDLFLTAVPPAL-PAGTQTLLLQSNSIVRVDQSE-LGYLANLTELDLSQNSFSDARD 110
Query: 160 FAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLI 219
F LP+L L+++ L ++ +FA L ++ + L HN++ +I AF+G + + +
Sbjct: 111 CDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRL 170
Query: 220 SLRNNPIKRILVHAFSGLNDVGQIELPSG--IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
L +N ++ I F L ++ +I + G + I F L + L LA M+L +
Sbjct: 171 HLNSNLLRAIDSRWFEMLPNL-EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
GL + LS ++ L + + + + + L++ N + +
Sbjct: 230 DYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRV 276
>BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 73.3 bits (172), Expect = 2e-12
Identities = 65/258 (25%), Positives = 113/258 (43%), Gaps = 6/258 (2%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
G ++T+L LS+ R F L QL L L+ LTR+ +F GL L+ELY+
Sbjct: 90 GYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLN 149
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
H L + AF+ L N+ + L N + I+S F + ++ + N + IL F
Sbjct: 150 HNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNF 209
Query: 235 SGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLR 293
L ++ + L +R I A GL+ + L L + + + L L
Sbjct: 210 RPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLN 269
Query: 294 ESDLGIIKVGSFDGLQHVDTLEICN-NKIDGIEELSLVQNNSVRVFKLTGNHMLE--SPE 350
++ L + G F + H+ L + N ++ I++ +LV + +T N L P
Sbjct: 270 KNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPR 329
Query: 351 AV--VLEVENIIIRGNHL 366
A + ++E +++ N L
Sbjct: 330 AFHHLPQMETLMLNNNAL 347
Score = 64.5 bits (150), Expect = 7e-10
Identities = 58/227 (25%), Positives = 106/227 (46%), Gaps = 7/227 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSL--SRADLRVLRSDAFAHLRQLRRLALDACNLTRIRP 159
V CN L VP L P+ TQ L S + +RV +S+ +L L L L + + R
Sbjct: 53 VDCNDLFLTAVPPAL-PAGTQTLLLQSNSIVRVDQSE-LGYLANLTELDLSQNSFSDARD 110
Query: 160 FAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLI 219
F LP+L L+++ L ++ +FA L ++ + L HN++ +I AF+G + + +
Sbjct: 111 CDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRL 170
Query: 220 SLRNNPIKRILVHAFSGLNDVGQIELPSG--IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
L +N ++ I F L ++ +I + G + I F L + L LA M+L +
Sbjct: 171 HLNSNLLRAIDSRWFEMLPNL-EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
GL + LS ++ L + + + + + L++ N + +
Sbjct: 230 DYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRV 276
>AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein.
Length = 713
Score = 73.3 bits (172), Expect = 2e-12
Identities = 65/258 (25%), Positives = 113/258 (43%), Gaps = 6/258 (2%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
G ++T+L LS+ R F L QL L L+ LTR+ +F GL L+ELY+
Sbjct: 90 GYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLN 149
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
H L + AF+ L N+ + L N + I+S F + ++ + N + IL F
Sbjct: 150 HNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNF 209
Query: 235 SGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLR 293
L ++ + L +R I A GL+ + L L + + + L L
Sbjct: 210 RPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLN 269
Query: 294 ESDLGIIKVGSFDGLQHVDTLEICN-NKIDGIEELSLVQNNSVRVFKLTGNHMLE--SPE 350
++ L + G F + H+ L + N ++ I++ +LV + +T N L P
Sbjct: 270 KNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPR 329
Query: 351 AV--VLEVENIIIRGNHL 366
A + ++E +++ N L
Sbjct: 330 AFHHLPQMETLMLNNNAL 347
Score = 64.5 bits (150), Expect = 7e-10
Identities = 58/227 (25%), Positives = 106/227 (46%), Gaps = 7/227 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSL--SRADLRVLRSDAFAHLRQLRRLALDACNLTRIRP 159
V CN L VP L P+ TQ L S + +RV +S+ +L L L L + + R
Sbjct: 53 VDCNDLFLTAVPPAL-PAGTQTLLLQSNSIVRVDQSE-LGYLANLTELDLSQNSFSDARD 110
Query: 160 FAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLI 219
F LP+L L+++ L ++ +FA L ++ + L HN++ +I AF+G + + +
Sbjct: 111 CDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRL 170
Query: 220 SLRNNPIKRILVHAFSGLNDVGQIELPSG--IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
L +N ++ I F L ++ +I + G + I F L + L LA M+L +
Sbjct: 171 HLNSNLLRAIDSRWFEMLPNL-EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
GL + LS ++ L + + + + + L++ N + +
Sbjct: 230 DYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRV 276
Score = 56.4 bits (130), Expect = 2e-07
Identities = 57/233 (24%), Positives = 104/233 (44%), Gaps = 4/233 (1%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
+GL+ S+ +L L+ L + AF+ L L RL L++ L I F LP L L I
Sbjct: 138 AGLA-SLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMI 196
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
+ + F L N+ S+VL + +I YA G + +S +N + R+ A
Sbjct: 197 GGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRA 256
Query: 234 FSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMD-LPSLLPDTFHGLIRVGRLS 291
+ + ++L ++ + P FA + + L L M+ L S+ L + +L
Sbjct: 257 LEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLD 316
Query: 292 LRESD-LGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
+ + L I +F L ++TL + NN + + + ++ +++ L GN
Sbjct: 317 ITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGN 369
>AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat
neuronal 5 protein.
Length = 713
Score = 73.3 bits (172), Expect = 2e-12
Identities = 65/258 (25%), Positives = 113/258 (43%), Gaps = 6/258 (2%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
G ++T+L LS+ R F L QL L L+ LTR+ +F GL L+ELY+
Sbjct: 90 GYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLN 149
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
H L + AF+ L N+ + L N + I+S F + ++ + N + IL F
Sbjct: 150 HNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNF 209
Query: 235 SGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLR 293
L ++ + L +R I A GL+ + L L + + + L L
Sbjct: 210 RPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLN 269
Query: 294 ESDLGIIKVGSFDGLQHVDTLEICN-NKIDGIEELSLVQNNSVRVFKLTGNHMLE--SPE 350
++ L + G F + H+ L + N ++ I++ +LV + +T N L P
Sbjct: 270 KNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPR 329
Query: 351 AV--VLEVENIIIRGNHL 366
A + ++E +++ N L
Sbjct: 330 AFHHLPQMETLMLNNNAL 347
Score = 64.5 bits (150), Expect = 7e-10
Identities = 58/227 (25%), Positives = 106/227 (46%), Gaps = 7/227 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSL--SRADLRVLRSDAFAHLRQLRRLALDACNLTRIRP 159
V CN L VP L P+ TQ L S + +RV +S+ +L L L L + + R
Sbjct: 53 VDCNDLFLTAVPPAL-PAGTQTLLLQSNSIVRVDQSE-LGYLANLTELDLSQNSFSDARD 110
Query: 160 FAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLI 219
F LP+L L+++ L ++ +FA L ++ + L HN++ +I AF+G + + +
Sbjct: 111 CDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRL 170
Query: 220 SLRNNPIKRILVHAFSGLNDVGQIELPSG--IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
L +N ++ I F L ++ +I + G + I F L + L LA M+L +
Sbjct: 171 HLNSNLLRAIDSRWFEMLPNL-EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
GL + LS ++ L + + + + + L++ N + +
Sbjct: 230 DYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRV 276
Score = 56.4 bits (130), Expect = 2e-07
Identities = 57/233 (24%), Positives = 104/233 (44%), Gaps = 4/233 (1%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
+GL+ S+ +L L+ L + AF+ L L RL L++ L I F LP L L I
Sbjct: 138 AGLA-SLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMI 196
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
+ + F L N+ S+VL + +I YA G + +S +N + R+ A
Sbjct: 197 GGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRA 256
Query: 234 FSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMD-LPSLLPDTFHGLIRVGRLS 291
+ + ++L ++ + P FA + + L L M+ L S+ L + +L
Sbjct: 257 LEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLD 316
Query: 292 LRESD-LGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
+ + L I +F L ++TL + NN + + + ++ +++ L GN
Sbjct: 317 ITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGN 369
>AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on
chromosome 1 protein protein.
Length = 713
Score = 73.3 bits (172), Expect = 2e-12
Identities = 65/258 (25%), Positives = 113/258 (43%), Gaps = 6/258 (2%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
G ++T+L LS+ R F L QL L L+ LTR+ +F GL L+ELY+
Sbjct: 90 GYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLN 149
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
H L + AF+ L N+ + L N + I+S F + ++ + N + IL F
Sbjct: 150 HNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNF 209
Query: 235 SGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLR 293
L ++ + L +R I A GL+ + L L + + + L L
Sbjct: 210 RPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLN 269
Query: 294 ESDLGIIKVGSFDGLQHVDTLEICN-NKIDGIEELSLVQNNSVRVFKLTGNHMLE--SPE 350
++ L + G F + H+ L + N ++ I++ +LV + +T N L P
Sbjct: 270 KNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPR 329
Query: 351 AV--VLEVENIIIRGNHL 366
A + ++E +++ N L
Sbjct: 330 AFHHLPQMETLMLNNNAL 347
Score = 64.5 bits (150), Expect = 7e-10
Identities = 58/227 (25%), Positives = 106/227 (46%), Gaps = 7/227 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSL--SRADLRVLRSDAFAHLRQLRRLALDACNLTRIRP 159
V CN L VP L P+ TQ L S + +RV +S+ +L L L L + + R
Sbjct: 53 VDCNDLFLTAVPPAL-PAGTQTLLLQSNSIVRVDQSE-LGYLANLTELDLSQNSFSDARD 110
Query: 160 FAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLI 219
F LP+L L+++ L ++ +FA L ++ + L HN++ +I AF+G + + +
Sbjct: 111 CDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRL 170
Query: 220 SLRNNPIKRILVHAFSGLNDVGQIELPSG--IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
L +N ++ I F L ++ +I + G + I F L + L LA M+L +
Sbjct: 171 HLNSNLLRAIDSRWFEMLPNL-EILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREIS 229
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
GL + LS ++ L + + + + + L++ N + +
Sbjct: 230 DYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRV 276
Score = 56.4 bits (130), Expect = 2e-07
Identities = 57/233 (24%), Positives = 104/233 (44%), Gaps = 4/233 (1%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
+GL+ S+ +L L+ L + AF+ L L RL L++ L I F LP L L I
Sbjct: 138 AGLA-SLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMI 196
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
+ + F L N+ S+VL + +I YA G + +S +N + R+ A
Sbjct: 197 GGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRA 256
Query: 234 FSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMD-LPSLLPDTFHGLIRVGRLS 291
+ + ++L ++ + P FA + + L L M+ L S+ L + +L
Sbjct: 257 LEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLD 316
Query: 292 LRESD-LGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
+ + L I +F L ++TL + NN + + + ++ +++ L GN
Sbjct: 317 ITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTVESLPNLQEVGLHGN 369
>AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein.
Length = 606
Score = 72.5 bits (170), Expect = 3e-12
Identities = 59/234 (25%), Positives = 109/234 (46%), Gaps = 2/234 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
GV +GLS ++T+L +S + +L F L L+ L + +L I AF GL L +
Sbjct: 123 GVFTGLS-NLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQ 181
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L ++ L V + A + L+++ S+ L H I + YAF + + + P+ ++
Sbjct: 182 LTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMM 241
Query: 231 -VHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
++ GLN + + T+ AF L + L L++ + ++ F LIR+
Sbjct: 242 PANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQE 301
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
L + + L I+ SF GL+ + L + N ++ +EE ++ V + N
Sbjct: 302 LHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNN 355
Score = 66.5 bits (155), Expect = 2e-10
Identities = 54/236 (22%), Positives = 104/236 (44%), Gaps = 4/236 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q++ V C+ L +P G+ L LS+ L+ + + F L + L +
Sbjct: 34 CSAQNKSVSCHRRRLIAIPEGIPIETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNII 93
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ P AF L LR L ++ L V F L N+T + ++ N+I + Y F +
Sbjct: 94 ANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLH 153
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDL 273
+ + + +N + I AFSGL + Q+ L + + +A + L + L L +++
Sbjct: 154 NLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNI 213
Query: 274 PSLLPDTFHGLIRVGRLSLRESD-LGIIKVGSFDGLQHVDTLEICNNKIDGIEELS 328
++ F L + L + L ++ S GL ++ +L + N + + L+
Sbjct: 214 NNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGL-NLTSLSVTNTNLSTVPFLA 268
Score = 57.2 bits (132), Expect = 1e-07
Identities = 49/205 (23%), Positives = 96/205 (46%), Gaps = 3/205 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L + DL + AF+ L L +L L+ CNLT + A L L L+++H +
Sbjct: 154 NLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNI 213
Query: 179 ATVDSFAFAALQNITSIVLTH-NRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
+ +AF L ++ + + + + + + + G N +L S+ N + + AF L
Sbjct: 214 NNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSL-SVTNTNLSTVPFLAFKHL 272
Query: 238 NDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESD 296
+ + L + I TIE F+ L + L + L ++ P +F GL + L++ ++
Sbjct: 273 VYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNL 332
Query: 297 LGIIKVGSFDGLQHVDTLEICNNKI 321
L ++ F + ++ L I NN +
Sbjct: 333 LETLEENVFSSPRALEVLSINNNPL 357
Score = 39.5 bits (88), Expect = 0.024
Identities = 22/84 (26%), Positives = 44/84 (52%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
+T L+LS + + + F+ L +L+ L + L I P +F+GL LR L + L
Sbjct: 275 LTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLE 334
Query: 180 TVDSFAFAALQNITSIVLTHNRIA 203
T++ F++ + + + + +N +A
Sbjct: 335 TLEENVFSSPRALEVLSINNNPLA 358
>AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat
neuronal 6C protein.
Length = 606
Score = 72.5 bits (170), Expect = 3e-12
Identities = 59/234 (25%), Positives = 109/234 (46%), Gaps = 2/234 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
GV +GLS ++T+L +S + +L F L L+ L + +L I AF GL L +
Sbjct: 123 GVFTGLS-NLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQ 181
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L ++ L V + A + L+++ S+ L H I + YAF + + + P+ ++
Sbjct: 182 LTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMM 241
Query: 231 -VHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
++ GLN + + T+ AF L + L L++ + ++ F LIR+
Sbjct: 242 PANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQE 301
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
L + + L I+ SF GL+ + L + N ++ +EE ++ V + N
Sbjct: 302 LHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNN 355
Score = 66.5 bits (155), Expect = 2e-10
Identities = 54/236 (22%), Positives = 104/236 (44%), Gaps = 4/236 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q++ V C+ L +P G+ L LS+ L+ + + F L + L +
Sbjct: 34 CSAQNKSVSCHRRRLIAIPEGIPIETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNII 93
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ P AF L LR L ++ L V F L N+T + ++ N+I + Y F +
Sbjct: 94 ANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLH 153
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDL 273
+ + + +N + I AFSGL + Q+ L + + +A + L + L L +++
Sbjct: 154 NLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNI 213
Query: 274 PSLLPDTFHGLIRVGRLSLRESD-LGIIKVGSFDGLQHVDTLEICNNKIDGIEELS 328
++ F L + L + L ++ S GL ++ +L + N + + L+
Sbjct: 214 NNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGL-NLTSLSVTNTNLSTVPFLA 268
Score = 57.2 bits (132), Expect = 1e-07
Identities = 49/205 (23%), Positives = 96/205 (46%), Gaps = 3/205 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L + DL + AF+ L L +L L+ CNLT + A L L L+++H +
Sbjct: 154 NLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNI 213
Query: 179 ATVDSFAFAALQNITSIVLTH-NRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
+ +AF L ++ + + + + + + + G N +L S+ N + + AF L
Sbjct: 214 NNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSL-SVTNTNLSTVPFLAFKHL 272
Query: 238 NDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESD 296
+ + L + I TIE F+ L + L + L ++ P +F GL + L++ ++
Sbjct: 273 VYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNL 332
Query: 297 LGIIKVGSFDGLQHVDTLEICNNKI 321
L ++ F + ++ L I NN +
Sbjct: 333 LETLEENVFSSPRALEVLSINNNPL 357
Score = 39.5 bits (88), Expect = 0.024
Identities = 22/84 (26%), Positives = 44/84 (52%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
+T L+LS + + + F+ L +L+ L + L I P +F+GL LR L + L
Sbjct: 275 LTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLE 334
Query: 180 TVDSFAFAALQNITSIVLTHNRIA 203
T++ F++ + + + + +N +A
Sbjct: 335 TLEENVFSSPRALEVLSINNNPLA 358
>AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens
cDNA FLJ31810 fis, clone NT2RI2009289, weakly similar to
CARBOXYPEPTIDASE N 83 KD CHAIN. ).
Length = 606
Score = 72.5 bits (170), Expect = 3e-12
Identities = 59/234 (25%), Positives = 109/234 (46%), Gaps = 2/234 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
GV +GLS ++T+L +S + +L F L L+ L + +L I AF GL L +
Sbjct: 123 GVFTGLS-NLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQ 181
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L ++ L V + A + L+++ S+ L H I + YAF + + + P+ ++
Sbjct: 182 LTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMM 241
Query: 231 -VHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
++ GLN + + T+ AF L + L L++ + ++ F LIR+
Sbjct: 242 PANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQE 301
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
L + + L I+ SF GL+ + L + N ++ +EE ++ V + N
Sbjct: 302 LHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNN 355
Score = 66.5 bits (155), Expect = 2e-10
Identities = 54/236 (22%), Positives = 104/236 (44%), Gaps = 4/236 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C +Q++ V C+ L +P G+ L LS+ L+ + + F L + L +
Sbjct: 34 CSAQNKSVSCHRRRLIAIPEGIPIETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNII 93
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ P AF L LR L ++ L V F L N+T + ++ N+I + Y F +
Sbjct: 94 ANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLH 153
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDL 273
+ + + +N + I AFSGL + Q+ L + + +A + L + L L +++
Sbjct: 154 NLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNI 213
Query: 274 PSLLPDTFHGLIRVGRLSLRESD-LGIIKVGSFDGLQHVDTLEICNNKIDGIEELS 328
++ F L + L + L ++ S GL ++ +L + N + + L+
Sbjct: 214 NNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGL-NLTSLSVTNTNLSTVPFLA 268
Score = 57.2 bits (132), Expect = 1e-07
Identities = 49/205 (23%), Positives = 96/205 (46%), Gaps = 3/205 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L + DL + AF+ L L +L L+ CNLT + A L L L+++H +
Sbjct: 154 NLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNI 213
Query: 179 ATVDSFAFAALQNITSIVLTH-NRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
+ +AF L ++ + + + + + + + G N +L S+ N + + AF L
Sbjct: 214 NNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSL-SVTNTNLSTVPFLAFKHL 272
Query: 238 NDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESD 296
+ + L + I TIE F+ L + L + L ++ P +F GL + L++ ++
Sbjct: 273 VYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNL 332
Query: 297 LGIIKVGSFDGLQHVDTLEICNNKI 321
L ++ F + ++ L I NN +
Sbjct: 333 LETLEENVFSSPRALEVLSINNNPL 357
Score = 39.5 bits (88), Expect = 0.024
Identities = 22/84 (26%), Positives = 44/84 (52%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
+T L+LS + + + F+ L +L+ L + L I P +F+GL LR L + L
Sbjct: 275 LTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLE 334
Query: 180 TVDSFAFAALQNITSIVLTHNRIA 203
T++ F++ + + + + +N +A
Sbjct: 335 TLEENVFSSPRALEVLSINNNPLA 358
>CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein.
Length = 473
Score = 72.1 bits (169), Expect = 4e-12
Identities = 48/149 (32%), Positives = 71/149 (47%), Gaps = 2/149 (1%)
Query: 122 QLSLS-RADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLAT 180
QL LS A LR + F L +L L LD C L + P FRGL L+ LY+Q L
Sbjct: 109 QLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQA 168
Query: 181 VDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDV 240
+ F L N+T + L NRI+ + AF G + ++ + L N + + HAF L +
Sbjct: 169 LPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRL 228
Query: 241 GQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
+ L + + + +A A L + L L
Sbjct: 229 MTLYLFANNLSALPTEALAPLRALQYLRL 257
Score = 68.5 bits (160), Expect = 5e-11
Identities = 61/256 (23%), Positives = 113/256 (44%), Gaps = 7/256 (2%)
Query: 164 GLPRLRE-LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
G+P + +++ ++ V + +F A +N+T + L N +A+I++ AF G + + L
Sbjct: 54 GIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLS 113
Query: 223 NNPIKRILVHA-FSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
+N R + A F GL + + L G++ + P F GL + L L L +L DT
Sbjct: 114 DNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDT 173
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L + L L + + + +F GL +D L + N++ + + + L
Sbjct: 174 FRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYL 233
Query: 341 TGNHMLESPE---AVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKV 397
N++ P A + ++ + + N C+C P L + + E C P ++
Sbjct: 234 FANNLSALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCSLPQRL 293
Query: 398 RGRSLAS-ATSGSAGC 412
GR L A + GC
Sbjct: 294 AGRDLKRLAANDLQGC 309
Score = 44.0 bits (99), Expect = 0.001
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G+ GL+ ++ L L L+ L D F L L L L ++ + AFRGL L
Sbjct: 148 GLFRGLA-ALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDR 206
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L + +A V AF L + ++ L N ++ + + A A + + L +NP
Sbjct: 207 LLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNP 261
>BC111067-1|AAI11068.1| 513|Homo sapiens leucine rich repeat
containing 24 protein.
Length = 513
Score = 72.1 bits (169), Expect = 4e-12
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 2/174 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C S + V C + LR VP G+ P L L ++ L A A L LRRL L +L
Sbjct: 29 CYSAT-VECGALRLRVVPLGIPPGTQTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLR 87
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ AFR PRL EL + L + S AF L + + L N++A++ + F
Sbjct: 88 ALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLARLLDFTFLHLPR 147
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLEL 268
+ + L+ N I+ + A +GL+ + ++L + + TI +A L + VL L
Sbjct: 148 LQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQVLRL 201
Score = 64.9 bits (151), Expect = 6e-10
Identities = 40/121 (33%), Positives = 63/121 (52%), Gaps = 3/121 (2%)
Query: 108 ALRGVPSGL---SPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRG 164
+LR + +G P + +L+L+ LR LRS AF L QLR L L L R+ F F
Sbjct: 85 SLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLARLLDFTFLH 144
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
LPRL+EL++Q + ++ A A L ++ + L+ N++ I A + ++ L N
Sbjct: 145 LPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQVLRLTEN 204
Query: 225 P 225
P
Sbjct: 205 P 205
Score = 31.5 bits (68), Expect = 6.4
Identities = 21/84 (25%), Positives = 37/84 (44%)
Query: 262 GIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
G L L ++ L P L + RL L + L ++ G+F + L + +N++
Sbjct: 51 GTQTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRL 110
Query: 322 DGIEELSLVQNNSVRVFKLTGNHM 345
G+ + V +RV L GN +
Sbjct: 111 RGLRSGAFVGLAQLRVLYLAGNQL 134
>BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor
protein.
Length = 473
Score = 72.1 bits (169), Expect = 4e-12
Identities = 48/149 (32%), Positives = 71/149 (47%), Gaps = 2/149 (1%)
Query: 122 QLSLS-RADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLAT 180
QL LS A LR + F L +L L LD C L + P FRGL L+ LY+Q L
Sbjct: 109 QLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQA 168
Query: 181 VDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDV 240
+ F L N+T + L NRI+ + AF G + ++ + L N + + HAF L +
Sbjct: 169 LPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRL 228
Query: 241 GQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
+ L + + + +A A L + L L
Sbjct: 229 MTLYLFANNLSALPTEALAPLRALQYLRL 257
Score = 68.5 bits (160), Expect = 5e-11
Identities = 61/256 (23%), Positives = 113/256 (44%), Gaps = 7/256 (2%)
Query: 164 GLPRLRE-LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
G+P + +++ ++ V + +F A +N+T + L N +A+I++ AF G + + L
Sbjct: 54 GIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLS 113
Query: 223 NNPIKRILVHA-FSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
+N R + A F GL + + L G++ + P F GL + L L L +L DT
Sbjct: 114 DNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDT 173
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L + L L + + + +F GL +D L + N++ + + + L
Sbjct: 174 FRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYL 233
Query: 341 TGNHMLESPE---AVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKV 397
N++ P A + ++ + + N C+C P L + + E C P ++
Sbjct: 234 FANNLSALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCSLPQRL 293
Query: 398 RGRSLAS-ATSGSAGC 412
GR L A + GC
Sbjct: 294 AGRDLKRLAANDLQGC 309
Score = 44.0 bits (99), Expect = 0.001
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G+ GL+ ++ L L L+ L D F L L L L ++ + AFRGL L
Sbjct: 148 GLFRGLA-ALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDR 206
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L + +A V AF L + ++ L N ++ + + A A + + L +NP
Sbjct: 207 LLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNP 261
>AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein.
Length = 473
Score = 72.1 bits (169), Expect = 4e-12
Identities = 48/149 (32%), Positives = 71/149 (47%), Gaps = 2/149 (1%)
Query: 122 QLSLS-RADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLAT 180
QL LS A LR + F L +L L LD C L + P FRGL L+ LY+Q L
Sbjct: 109 QLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQA 168
Query: 181 VDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDV 240
+ F L N+T + L NRI+ + AF G + ++ + L N + + HAF L +
Sbjct: 169 LPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRL 228
Query: 241 GQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
+ L + + + +A A L + L L
Sbjct: 229 MTLYLFANNLSALPTEALAPLRALQYLRL 257
Score = 68.5 bits (160), Expect = 5e-11
Identities = 61/256 (23%), Positives = 113/256 (44%), Gaps = 7/256 (2%)
Query: 164 GLPRLRE-LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
G+P + +++ ++ V + +F A +N+T + L N +A+I++ AF G + + L
Sbjct: 54 GIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLS 113
Query: 223 NNPIKRILVHA-FSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
+N R + A F GL + + L G++ + P F GL + L L L +L DT
Sbjct: 114 DNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDT 173
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L + L L + + + +F GL +D L + N++ + + + L
Sbjct: 174 FRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYL 233
Query: 341 TGNHMLESPE---AVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKV 397
N++ P A + ++ + + N C+C P L + + E C P ++
Sbjct: 234 FANNLSALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCSLPQRL 293
Query: 398 RGRSLAS-ATSGSAGC 412
GR L A + GC
Sbjct: 294 AGRDLKRLAANDLQGC 309
Score = 44.0 bits (99), Expect = 0.001
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G+ GL+ ++ L L L+ L D F L L L L ++ + AFRGL L
Sbjct: 148 GLFRGLA-ALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDR 206
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L + +A V AF L + ++ L N ++ + + A A + + L +NP
Sbjct: 207 LLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNP 261
>AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 72.1 bits (169), Expect = 4e-12
Identities = 53/224 (23%), Positives = 102/224 (45%), Gaps = 2/224 (0%)
Query: 99 QSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIR 158
++++ C + L+ VP +S +VT LSL + + L F +L+++ L + I
Sbjct: 119 ETELECVNGDLKSVPM-ISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHIS 177
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINL 218
AF GL L+ LY+ H + T+ F L +T ++L N I +I F G N +
Sbjct: 178 RKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFF 237
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+S+ NN ++ + + + + ++L I+ + F + + VL L + +
Sbjct: 238 LSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVP 297
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
TF L +G L L + + + F L+ + L + +N +
Sbjct: 298 EKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPL 341
Score = 42.7 bits (96), Expect = 0.003
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 1/150 (0%)
Query: 213 TNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFM 271
+N + L+SL+ N I + F + +I L IR I +AF GL + +L L
Sbjct: 136 SNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHN 195
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+ +L P F L ++ L L ++ + I F GL + L + NN ++ + + Q
Sbjct: 196 CITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQ 255
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVENIII 361
+ L GN + + L +++ +
Sbjct: 256 MPQLNWVDLEGNRIKYLTNSTFLSCDSLTV 285
Score = 42.3 bits (95), Expect = 0.003
Identities = 28/132 (21%), Positives = 59/132 (44%), Gaps = 1/132 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
+GL+ S+ LS+ L L A + QL + L+ + + F L L++
Sbjct: 230 TGLN-SLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFL 288
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
+ V F++L+N+ + L+ N I ++ + F + ++L +NP+ + +
Sbjct: 289 PRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQ 348
Query: 234 FSGLNDVGQIEL 245
F L + ++L
Sbjct: 349 FESLKQLQSLDL 360
Score = 36.3 bits (80), Expect = 0.22
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 1/170 (0%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
N+T + L N+I + F + I L++N I+ I AF GL ++ + L I
Sbjct: 138 NVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCI 197
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
T+ P F L + L L + + F GL + LS+ + L + +
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 310 HVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI 359
++ +++ N+I + + + +S+ V L N + PE ++N+
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNL 307
>AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 72.1 bits (169), Expect = 4e-12
Identities = 53/224 (23%), Positives = 102/224 (45%), Gaps = 2/224 (0%)
Query: 99 QSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIR 158
++++ C + L+ VP +S +VT LSL + + L F +L+++ L + I
Sbjct: 119 ETELECVNGDLKSVPM-ISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHIS 177
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINL 218
AF GL L+ LY+ H + T+ F L +T ++L N I +I F G N +
Sbjct: 178 RKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFF 237
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+S+ NN ++ + + + + ++L I+ + F + + VL L + +
Sbjct: 238 LSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVP 297
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
TF L +G L L + + + F L+ + L + +N +
Sbjct: 298 EKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPL 341
Score = 42.7 bits (96), Expect = 0.003
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 1/150 (0%)
Query: 213 TNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFM 271
+N + L+SL+ N I + F + +I L IR I +AF GL + +L L
Sbjct: 136 SNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHN 195
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+ +L P F L ++ L L ++ + I F GL + L + NN ++ + + Q
Sbjct: 196 CITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQ 255
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVENIII 361
+ L GN + + L +++ +
Sbjct: 256 MPQLNWVDLEGNRIKYLTNSTFLSCDSLTV 285
Score = 42.3 bits (95), Expect = 0.003
Identities = 28/132 (21%), Positives = 59/132 (44%), Gaps = 1/132 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
+GL+ S+ LS+ L L A + QL + L+ + + F L L++
Sbjct: 230 TGLN-SLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFL 288
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
+ V F++L+N+ + L+ N I ++ + F + ++L +NP+ + +
Sbjct: 289 PRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQ 348
Query: 234 FSGLNDVGQIEL 245
F L + ++L
Sbjct: 349 FESLKQLQSLDL 360
Score = 36.3 bits (80), Expect = 0.22
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 1/170 (0%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
N+T + L N+I + F + I L++N I+ I AF GL ++ + L I
Sbjct: 138 NVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCI 197
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
T+ P F L + L L + + F GL + LS+ + L + +
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 310 HVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI 359
++ +++ N+I + + + +S+ V L N + PE ++N+
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNL 307
>AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled receptor
affecting testicular descent protein.
Length = 754
Score = 72.1 bits (169), Expect = 4e-12
Identities = 53/224 (23%), Positives = 102/224 (45%), Gaps = 2/224 (0%)
Query: 99 QSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIR 158
++++ C + L+ VP +S +VT LSL + + L F +L+++ L + I
Sbjct: 119 ETELECVNGDLKSVPM-ISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHIS 177
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINL 218
AF GL L+ LY+ H + T+ F L +T ++L N I +I F G N +
Sbjct: 178 RKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFF 237
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+S+ NN ++ + + + + ++L I+ + F + + VL L + +
Sbjct: 238 LSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVP 297
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
TF L +G L L + + + F L+ + L + +N +
Sbjct: 298 EKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPL 341
Score = 42.7 bits (96), Expect = 0.003
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 1/150 (0%)
Query: 213 TNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFM 271
+N + L+SL+ N I + F + +I L IR I +AF GL + +L L
Sbjct: 136 SNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHN 195
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+ +L P F L ++ L L ++ + I F GL + L + NN ++ + + Q
Sbjct: 196 CITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQ 255
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVENIII 361
+ L GN + + L +++ +
Sbjct: 256 MPQLNWVDLEGNRIKYLTNSTFLSCDSLTV 285
Score = 42.3 bits (95), Expect = 0.003
Identities = 28/132 (21%), Positives = 59/132 (44%), Gaps = 1/132 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
+GL+ S+ LS+ L L A + QL + L+ + + F L L++
Sbjct: 230 TGLN-SLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFL 288
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
+ V F++L+N+ + L+ N I ++ + F + ++L +NP+ + +
Sbjct: 289 PRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQ 348
Query: 234 FSGLNDVGQIEL 245
F L + ++L
Sbjct: 349 FESLKQLQSLDL 360
Score = 36.3 bits (80), Expect = 0.22
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 1/170 (0%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
N+T + L N+I + F + I L++N I+ I AF GL ++ + L I
Sbjct: 138 NVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCI 197
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
T+ P F L + L L + + F GL + LS+ + L + +
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 310 HVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI 359
++ +++ N+I + + + +S+ V L N + PE ++N+
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNL 307
>AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein.
Length = 754
Score = 72.1 bits (169), Expect = 4e-12
Identities = 53/224 (23%), Positives = 102/224 (45%), Gaps = 2/224 (0%)
Query: 99 QSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIR 158
++++ C + L+ VP +S +VT LSL + + L F +L+++ L + I
Sbjct: 119 ETELECVNGDLKSVPM-ISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHIS 177
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINL 218
AF GL L+ LY+ H + T+ F L +T ++L N I +I F G N +
Sbjct: 178 RKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFF 237
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+S+ NN ++ + + + + ++L I+ + F + + VL L + +
Sbjct: 238 LSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVP 297
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
TF L +G L L + + + F L+ + L + +N +
Sbjct: 298 EKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPL 341
Score = 42.7 bits (96), Expect = 0.003
Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 1/150 (0%)
Query: 213 TNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFM 271
+N + L+SL+ N I + F + +I L IR I +AF GL + +L L
Sbjct: 136 SNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHN 195
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+ +L P F L ++ L L ++ + I F GL + L + NN ++ + + Q
Sbjct: 196 CITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQ 255
Query: 332 NNSVRVFKLTGNHMLESPEAVVLEVENIII 361
+ L GN + + L +++ +
Sbjct: 256 MPQLNWVDLEGNRIKYLTNSTFLSCDSLTV 285
Score = 42.3 bits (95), Expect = 0.003
Identities = 28/132 (21%), Positives = 59/132 (44%), Gaps = 1/132 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
+GL+ S+ LS+ L L A + QL + L+ + + F L L++
Sbjct: 230 TGLN-SLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFL 288
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
+ V F++L+N+ + L+ N I ++ + F + ++L +NP+ + +
Sbjct: 289 PRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQ 348
Query: 234 FSGLNDVGQIEL 245
F L + ++L
Sbjct: 349 FESLKQLQSLDL 360
Score = 36.3 bits (80), Expect = 0.22
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 1/170 (0%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
N+T + L N+I + F + I L++N I+ I AF GL ++ + L I
Sbjct: 138 NVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCI 197
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
T+ P F L + L L + + F GL + LS+ + L + +
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 310 HVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI 359
++ +++ N+I + + + +S+ V L N + PE ++N+
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNL 307
>AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein.
Length = 473
Score = 72.1 bits (169), Expect = 4e-12
Identities = 48/149 (32%), Positives = 71/149 (47%), Gaps = 2/149 (1%)
Query: 122 QLSLS-RADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLAT 180
QL LS A LR + F L +L L LD C L + P FRGL L+ LY+Q L
Sbjct: 109 QLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQA 168
Query: 181 VDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDV 240
+ F L N+T + L NRI+ + AF G + ++ + L N + + HAF L +
Sbjct: 169 LPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRL 228
Query: 241 GQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
+ L + + + +A A L + L L
Sbjct: 229 MTLYLFANNLSALPTEALAPLRALQYLRL 257
Score = 68.5 bits (160), Expect = 5e-11
Identities = 61/256 (23%), Positives = 113/256 (44%), Gaps = 7/256 (2%)
Query: 164 GLPRLRE-LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
G+P + +++ ++ V + +F A +N+T + L N +A+I++ AF G + + L
Sbjct: 54 GIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLS 113
Query: 223 NNPIKRILVHA-FSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
+N R + A F GL + + L G++ + P F GL + L L L +L DT
Sbjct: 114 DNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDT 173
Query: 281 FHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKL 340
F L + L L + + + +F GL +D L + N++ + + + L
Sbjct: 174 FRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYL 233
Query: 341 TGNHMLESPE---AVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKV 397
N++ P A + ++ + + N C+C P L + + E C P ++
Sbjct: 234 FANNLSALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWLQKFRGSSSEVPCSLPQRL 293
Query: 398 RGRSLAS-ATSGSAGC 412
GR L A + GC
Sbjct: 294 AGRDLKRLAANDLQGC 309
Score = 44.0 bits (99), Expect = 0.001
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G+ GL+ ++ L L L+ L D F L L L L ++ + AFRGL L
Sbjct: 148 GLFRGLA-ALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDR 206
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L + +A V AF L + ++ L N ++ + + A A + + L +NP
Sbjct: 207 LLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNP 261
>AB178281-1|BAD97811.1| 513|Homo sapiens LRRC24 protein protein.
Length = 513
Score = 72.1 bits (169), Expect = 4e-12
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 2/174 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C S + V C + LR VP G+ P L L ++ L A A L LRRL L +L
Sbjct: 29 CYSAT-VECGALRLRVVPLGIPPGTQTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLR 87
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ AFR PRL EL + L + S AF L + + L N++A++ + F
Sbjct: 88 ALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLARLLDFTFLHLPR 147
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLEL 268
+ + L+ N I+ + A +GL+ + ++L + + TI +A L + VL L
Sbjct: 148 LQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQVLRL 201
Score = 64.9 bits (151), Expect = 6e-10
Identities = 40/121 (33%), Positives = 63/121 (52%), Gaps = 3/121 (2%)
Query: 108 ALRGVPSGL---SPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRG 164
+LR + +G P + +L+L+ LR LRS AF L QLR L L L R+ F F
Sbjct: 85 SLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLARLLDFTFLH 144
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
LPRL+EL++Q + ++ A A L ++ + L+ N++ I A + ++ L N
Sbjct: 145 LPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQVLRLTEN 204
Query: 225 P 225
P
Sbjct: 205 P 205
Score = 31.5 bits (68), Expect = 6.4
Identities = 21/84 (25%), Positives = 37/84 (44%)
Query: 262 GIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
G L L ++ L P L + RL L + L ++ G+F + L + +N++
Sbjct: 51 GTQTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRL 110
Query: 322 DGIEELSLVQNNSVRVFKLTGNHM 345
G+ + V +RV L GN +
Sbjct: 111 RGLRSGAFVGLAQLRVLYLAGNQL 134
>M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein
protein.
Length = 359
Score = 71.7 bits (168), Expect = 5e-12
Identities = 59/246 (23%), Positives = 102/246 (41%), Gaps = 8/246 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L VP L P T L L + ++ F +L+ L L L ++++ P A
Sbjct: 65 VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGA 124
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L LY+ L + LQ + + N I ++ F G N + +I L
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRA---HENEITKVRKVTFNGLNQMIVIEL 181
Query: 222 RNNPIKRILVH--AFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP+K + AF G+ + I + T PQ + L L + +
Sbjct: 182 GTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP--PSLTELHLDGNKISRVDAA 239
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
+ GL + +L L + + + GS H+ L + NNK+ + L ++ ++V
Sbjct: 240 SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG-GLAEHKYIQVVY 298
Query: 340 LTGNHM 345
L N++
Sbjct: 299 LHNNNI 304
>CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein.
Length = 359
Score = 71.7 bits (168), Expect = 5e-12
Identities = 59/246 (23%), Positives = 102/246 (41%), Gaps = 8/246 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L VP L P T L L + ++ F +L+ L L L ++++ P A
Sbjct: 65 VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGA 124
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L LY+ L + LQ + + N I ++ F G N + +I L
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRA---HENEITKVRKVTFNGLNQMIVIEL 181
Query: 222 RNNPIKRILVH--AFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP+K + AF G+ + I + T PQ + L L + +
Sbjct: 182 GTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP--PSLTELHLDGNKISRVDAA 239
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
+ GL + +L L + + + GS H+ L + NNK+ + L ++ ++V
Sbjct: 240 SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG-GLAEHKYIQVVY 298
Query: 340 LTGNHM 345
L N++
Sbjct: 299 LHNNNI 304
>CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein.
Length = 359
Score = 71.7 bits (168), Expect = 5e-12
Identities = 59/246 (23%), Positives = 102/246 (41%), Gaps = 8/246 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L VP L P T L L + ++ F +L+ L L L ++++ P A
Sbjct: 65 VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGA 124
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L LY+ L + LQ + + N I ++ F G N + +I L
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRA---HENEITKVRKVTFNGLNQMIVIEL 181
Query: 222 RNNPIKRILVH--AFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP+K + AF G+ + I + T PQ + L L + +
Sbjct: 182 GTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP--PSLTELHLDGNKISRVDAA 239
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
+ GL + +L L + + + GS H+ L + NNK+ + L ++ ++V
Sbjct: 240 SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG-GLAEHKYIQVVY 298
Query: 340 LTGNHM 345
L N++
Sbjct: 299 LHNNNI 304
>BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 71.7 bits (168), Expect = 5e-12
Identities = 59/246 (23%), Positives = 102/246 (41%), Gaps = 8/246 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L VP L P T L L + ++ F +L+ L L L ++++ P A
Sbjct: 65 VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGA 124
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L LY+ L + LQ + + N I ++ F G N + +I L
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRA---HENEITKVRKVTFNGLNQMIVIEL 181
Query: 222 RNNPIKRILVH--AFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP+K + AF G+ + I + T PQ + L L + +
Sbjct: 182 GTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP--PSLTELHLDGNKISRVDAA 239
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
+ GL + +L L + + + GS H+ L + NNK+ + L ++ ++V
Sbjct: 240 SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG-GLAEHKYIQVVY 298
Query: 340 LTGNHM 345
L N++
Sbjct: 299 LHNNNI 304
>BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 71.7 bits (168), Expect = 5e-12
Identities = 59/246 (23%), Positives = 102/246 (41%), Gaps = 8/246 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L VP L P T L L + ++ F +L+ L L L ++++ P A
Sbjct: 65 VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGA 124
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L LY+ L + LQ + + N I ++ F G N + +I L
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRA---HENEITKVRKVTFNGLNQMIVIEL 181
Query: 222 RNNPIKRILVH--AFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP+K + AF G+ + I + T PQ + L L + +
Sbjct: 182 GTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP--PSLTELHLDGNKISRVDAA 239
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
+ GL + +L L + + + GS H+ L + NNK+ + L ++ ++V
Sbjct: 240 SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG-GLAEHKYIQVVY 298
Query: 340 LTGNHM 345
L N++
Sbjct: 299 LHNNNI 304
>AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 71.7 bits (168), Expect = 5e-12
Identities = 59/246 (23%), Positives = 102/246 (41%), Gaps = 8/246 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L VP L P T L L + ++ F +L+ L L L ++++ P A
Sbjct: 65 VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGA 124
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L LY+ L + LQ + + N I ++ F G N + +I L
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRA---HENEITKVRKVTFNGLNQMIVIEL 181
Query: 222 RNNPIKRILVH--AFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP+K + AF G+ + I + T PQ + L L + +
Sbjct: 182 GTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP--PSLTELHLDGNKISRVDAA 239
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
+ GL + +L L + + + GS H+ L + NNK+ + L ++ ++V
Sbjct: 240 SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG-GLAEHKYIQVVY 298
Query: 340 LTGNHM 345
L N++
Sbjct: 299 LHNNNI 304
>AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein.
Length = 359
Score = 71.7 bits (168), Expect = 5e-12
Identities = 59/246 (23%), Positives = 102/246 (41%), Gaps = 8/246 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L VP L P T L L + ++ F +L+ L L L ++++ P A
Sbjct: 65 VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGA 124
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L LY+ L + LQ + + N I ++ F G N + +I L
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRA---HENEITKVRKVTFNGLNQMIVIEL 181
Query: 222 RNNPIKRILVH--AFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP+K + AF G+ + I + T PQ + L L + +
Sbjct: 182 GTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP--PSLTELHLDGNKISRVDAA 239
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
+ GL + +L L + + + GS H+ L + NNK+ + L ++ ++V
Sbjct: 240 SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPG-GLAEHKYIQVVY 298
Query: 340 LTGNHM 345
L N++
Sbjct: 299 LHNNNI 304
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase
protein.
Length = 1463
Score = 71.3 bits (167), Expect = 6e-12
Identities = 45/133 (33%), Positives = 68/133 (51%), Gaps = 1/133 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSG 248
Q T + L NRI +I AF +N + L NN I++I +AF GL ++ + L +
Sbjct: 50 QQTTVLDLRFNRIREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNE 109
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I ++ Q F GL + L +F L L P+TF L+R+ RL L + L I GSF L
Sbjct: 110 IHALDKQTFKGLISLEHLVYSFHQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNL 169
Query: 309 QHVDTLEICNNKI 321
+ L + +N +
Sbjct: 170 DSLKRLRLDSNAL 182
Score = 55.6 bits (128), Expect = 3e-07
Identities = 39/153 (25%), Positives = 70/153 (45%), Gaps = 2/153 (1%)
Query: 96 CLS-QSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
CL +S V C L +P + T L L +R + AF L+ L L L+ ++
Sbjct: 28 CLCFKSTVRCMHLMLDHIPQ-VPQQTTVLDLRFNRIREIPGSAFKKLKNLNTLLLNNNHI 86
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+I AF GL L LY+ + +D F L ++ +V + +++ ++ F
Sbjct: 87 RKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLVYSFHQLEMLQPETFGDLL 146
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+ + L NN + +I +FS L+ + ++ L S
Sbjct: 147 RLERLFLHNNKLSKIPAGSFSNLDSLKRLRLDS 179
Score = 49.2 bits (112), Expect = 3e-05
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 1/130 (0%)
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSL 276
++ LR N I+ I AF L ++ + L + IR I AF GLE + L L ++ +L
Sbjct: 54 VLDLRFNRIREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHAL 113
Query: 277 LPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVR 336
TF GLI + L L +++ +F L ++ L + NNK+ I S +S++
Sbjct: 114 DKQTFKGLISLEHLVYSFHQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLK 173
Query: 337 VFKLTGNHML 346
+L N ++
Sbjct: 174 RLRLDSNALV 183
Score = 32.7 bits (71), Expect = 2.8
Identities = 23/108 (21%), Positives = 48/108 (44%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L L+ +R + +AF L L L L + + F+GL L L L
Sbjct: 75 NLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLVYSFHQL 134
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
+ F L + + L +N++++I + +F+ + + + L +N +
Sbjct: 135 EMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLKRLRLDSNAL 182
>AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein.
Length = 593
Score = 71.3 bits (167), Expect = 6e-12
Identities = 68/257 (26%), Positives = 108/257 (42%), Gaps = 4/257 (1%)
Query: 96 CLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C SQ Q V+C L VP GL L LS L L+ + L L+ L L L
Sbjct: 37 CTSQPQAVLCGHRQLEAVPGGLPLDTELLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQL 96
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + P AF GL L L +Q L + F+ L +T + L N+I AF
Sbjct: 97 STLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELG 156
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDL 273
+ + + +N + + AF+GL + + L + T+ A A L + L L +D+
Sbjct: 157 SLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDI 216
Query: 274 PSLLPDTFHGLIRVGRLSLR-ESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQN 332
L GL ++ L + L + GS GL ++ +L I + + +L
Sbjct: 217 GRLPAGALRGLGQLKELEIHLWPSLEALDPGSLVGL-NLSSLAITRCNLSSVPFQALYHL 275
Query: 333 NSVRVFKLTGNHMLESP 349
+ +RV L+ N + P
Sbjct: 276 SFLRVLDLSQNPISAIP 292
Score = 68.1 bits (159), Expect = 6e-11
Identities = 58/234 (24%), Positives = 107/234 (45%), Gaps = 2/234 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
GV SGLS ++T L L + + AF L L++L + +L + P AF GL +L
Sbjct: 126 GVFSGLS-ALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLST 184
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP-IKRI 229
L ++ L+TV A A L + ++ L I ++ + A G + + + P ++ +
Sbjct: 185 LTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIHLWPSLEAL 244
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
+ GLN + ++ QA L + VL+L+ + ++ L+R+
Sbjct: 245 DPGSLVGLNLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQE 304
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
L L + L I +F GL L++ +N + +EE + + + +L+GN
Sbjct: 305 LRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGN 358
>AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat
neuronal 6D protein.
Length = 593
Score = 71.3 bits (167), Expect = 6e-12
Identities = 68/257 (26%), Positives = 108/257 (42%), Gaps = 4/257 (1%)
Query: 96 CLSQSQ-VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C SQ Q V+C L VP GL L LS L L+ + L L+ L L L
Sbjct: 37 CTSQPQAVLCGHRQLEAVPGGLPLDTELLDLSGNRLWGLQQGMLSRLSLLQELDLSYNQL 96
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + P AF GL L L +Q L + F+ L +T + L N+I AF
Sbjct: 97 STLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDGAFGELG 156
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDL 273
+ + + +N + + AF+GL + + L + T+ A A L + L L +D+
Sbjct: 157 SLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALRLRELDI 216
Query: 274 PSLLPDTFHGLIRVGRLSLR-ESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQN 332
L GL ++ L + L + GS GL ++ +L I + + +L
Sbjct: 217 GRLPAGALRGLGQLKELEIHLWPSLEALDPGSLVGL-NLSSLAITRCNLSSVPFQALYHL 275
Query: 333 NSVRVFKLTGNHMLESP 349
+ +RV L+ N + P
Sbjct: 276 SFLRVLDLSQNPISAIP 292
Score = 68.1 bits (159), Expect = 6e-11
Identities = 58/234 (24%), Positives = 107/234 (45%), Gaps = 2/234 (0%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
GV SGLS ++T L L + + AF L L++L + +L + P AF GL +L
Sbjct: 126 GVFSGLS-ALTLLDLRLNQIVLFLDGAFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLST 184
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP-IKRI 229
L ++ L+TV A A L + ++ L I ++ + A G + + + P ++ +
Sbjct: 185 LTLERCNLSTVPGLALARLPALVALRLRELDIGRLPAGALRGLGQLKELEIHLWPSLEAL 244
Query: 230 LVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
+ GLN + ++ QA L + VL+L+ + ++ L+R+
Sbjct: 245 DPGSLVGLNLSSLAITRCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQE 304
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
L L + L I +F GL L++ +N + +EE + + + +L+GN
Sbjct: 305 LRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGN 358
>Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V
precursor protein.
Length = 560
Score = 70.9 bits (166), Expect = 8e-12
Identities = 70/300 (23%), Positives = 120/300 (40%), Gaps = 8/300 (2%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L LS +L L +L RL L + L + L L EL + ++
Sbjct: 175 LDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIA 234
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF L N++S+ L+ N +A + S F ++ + L++L NP+ + F + + +
Sbjct: 235 PGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQE 294
Query: 243 IELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD-TFHGLIRVGRLSLRESDLGII 300
+ L + +RT+ AF L + L + S LP F GL + L+L + L +
Sbjct: 295 LWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTAL 354
Query: 301 KVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV---VLEVE 357
G GL + + + N++ + +S+ +L N + P V + +
Sbjct: 355 PDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLT 414
Query: 358 NIIIRGNHLPCECGRDPFTNPLALSQDFA---EENYCISPLKVRGRSLASATSGSAGCRG 414
+++ N C+CG PF L E C P G L + G A C G
Sbjct: 415 EVLLGHNSWRCDCGLGPFLGWLRQHLGLVGGEEPPRCAGPGAHAGLPLWALPGGDAECPG 474
Score = 58.0 bits (134), Expect = 6e-08
Identities = 50/210 (23%), Positives = 89/210 (42%), Gaps = 2/210 (0%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
G + +L L L L S L L L ++ I P AF LP L L +
Sbjct: 191 GAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLS 250
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
LA + S F N+T + L N +A++ F + + L ++ + AF
Sbjct: 251 RNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAF 310
Query: 235 SGLNDVGQ--IELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
L+ + + L + + AF GL + VL L L +L GL ++ ++SL
Sbjct: 311 RNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSL 370
Query: 293 RESDLGIIKVGSFDGLQHVDTLEICNNKID 322
R + L + F L ++++++ +N+++
Sbjct: 371 RRNRLRALPRALFRNLSSLESVQLDHNQLE 400
Score = 46.8 bits (106), Expect = 2e-04
Identities = 42/202 (20%), Positives = 87/202 (43%), Gaps = 1/202 (0%)
Query: 161 AFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLIS 220
+F G+ L+ L I + ++ V F+ L + ++ L+ N+I + + +
Sbjct: 69 SFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLF 128
Query: 221 LRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQA-FAGLEGIGVLELAFMDLPSLLPD 279
L +N ++ I + F L ++ ++ L P + F LE + +L+L+ +L L
Sbjct: 129 LDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKG 188
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
++ RL L + L + G + L + L+ N I I + + ++
Sbjct: 189 LLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLT 248
Query: 340 LTGNHMLESPEAVVLEVENIII 361
L+ NH+ P A+ L N+ +
Sbjct: 249 LSRNHLAFLPSALFLHSHNLTL 270
Score = 46.0 bits (104), Expect = 3e-04
Identities = 35/140 (25%), Positives = 62/140 (44%), Gaps = 1/140 (0%)
Query: 107 AALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDAC-NLTRIRPFAFRGL 165
A L GV G + +L L+R LR L + AF +L +LR L + L+ + AF+GL
Sbjct: 279 AELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGL 338
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L+ L + L + L + + L NR+ + F + + + L +N
Sbjct: 339 GELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQ 398
Query: 226 IKRILVHAFSGLNDVGQIEL 245
++ + F L + ++ L
Sbjct: 399 LETLPGDVFGALPRLTEVLL 418
Score = 39.9 bits (89), Expect = 0.018
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 106 SAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL 165
SA +G GL + L+L L L L +LR+++L L + FR L
Sbjct: 328 SALPQGAFQGLG-ELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNL 386
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHN 200
L + + H L T+ F AL +T ++L HN
Sbjct: 387 SSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHN 421
Score = 39.1 bits (87), Expect = 0.032
Identities = 30/134 (22%), Positives = 62/134 (46%), Gaps = 5/134 (3%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIR 250
N+T I+L ++S +F+G + + + ++ I + FS L + + L
Sbjct: 51 NLTHILLFGMGRGVLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKI 110
Query: 251 TIEPQAFAGLEGIGVLELAFMD---LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
T P A L+ + +LE F+D L + + F L+ + L+L ++ L + F
Sbjct: 111 THLPGAL--LDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTN 168
Query: 308 LQHVDTLEICNNKI 321
L+++ L++ N +
Sbjct: 169 LENLKLLDLSGNNL 182
Score = 34.3 bits (75), Expect = 0.90
Identities = 22/112 (19%), Positives = 55/112 (49%)
Query: 248 GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
G ++ Q+F+G+ + L ++ + ++ P TF LI++ L L + + + D
Sbjct: 61 GRGVLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDK 120
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI 359
+ ++ L + +N + GI++ + +++ L N + P ++ +EN+
Sbjct: 121 MVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENL 172
>L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane
glycoprotein V protein.
Length = 560
Score = 70.9 bits (166), Expect = 8e-12
Identities = 70/300 (23%), Positives = 120/300 (40%), Gaps = 8/300 (2%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L LS +L L +L RL L + L + L L EL + ++
Sbjct: 175 LDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIA 234
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF L N++S+ L+ N +A + S F ++ + L++L NP+ + F + + +
Sbjct: 235 PGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQE 294
Query: 243 IELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD-TFHGLIRVGRLSLRESDLGII 300
+ L + +RT+ AF L + L + S LP F GL + L+L + L +
Sbjct: 295 LWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTAL 354
Query: 301 KVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV---VLEVE 357
G GL + + + N++ + +S+ +L N + P V + +
Sbjct: 355 PDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLT 414
Query: 358 NIIIRGNHLPCECGRDPFTNPLALSQDFA---EENYCISPLKVRGRSLASATSGSAGCRG 414
+++ N C+CG PF L E C P G L + G A C G
Sbjct: 415 EVLLGHNSWRCDCGLGPFLGWLRQHLGLVGGEEPPRCAGPGAHAGLPLWALPGGDAECPG 474
Score = 58.0 bits (134), Expect = 6e-08
Identities = 50/210 (23%), Positives = 89/210 (42%), Gaps = 2/210 (0%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
G + +L L L L S L L L ++ I P AF LP L L +
Sbjct: 191 GAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLS 250
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
LA + S F N+T + L N +A++ F + + L ++ + AF
Sbjct: 251 RNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAF 310
Query: 235 SGLNDVGQ--IELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
L+ + + L + + AF GL + VL L L +L GL ++ ++SL
Sbjct: 311 RNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSL 370
Query: 293 RESDLGIIKVGSFDGLQHVDTLEICNNKID 322
R + L + F L ++++++ +N+++
Sbjct: 371 RRNRLRALPRALFRNLSSLESVQLDHNQLE 400
Score = 46.8 bits (106), Expect = 2e-04
Identities = 42/202 (20%), Positives = 87/202 (43%), Gaps = 1/202 (0%)
Query: 161 AFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLIS 220
+F G+ L+ L I + ++ V F+ L + ++ L+ N+I + + +
Sbjct: 69 SFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLF 128
Query: 221 LRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQA-FAGLEGIGVLELAFMDLPSLLPD 279
L +N ++ I + F L ++ ++ L P + F LE + +L+L+ +L L
Sbjct: 129 LDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKG 188
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFK 339
++ RL L + L + G + L + L+ N I I + + ++
Sbjct: 189 LLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLT 248
Query: 340 LTGNHMLESPEAVVLEVENIII 361
L+ NH+ P A+ L N+ +
Sbjct: 249 LSRNHLAFLPSALFLHSHNLTL 270
Score = 46.0 bits (104), Expect = 3e-04
Identities = 35/140 (25%), Positives = 62/140 (44%), Gaps = 1/140 (0%)
Query: 107 AALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDAC-NLTRIRPFAFRGL 165
A L GV G + +L L+R LR L + AF +L +LR L + L+ + AF+GL
Sbjct: 279 AELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGL 338
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L+ L + L + L + + L NR+ + F + + + L +N
Sbjct: 339 GELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQ 398
Query: 226 IKRILVHAFSGLNDVGQIEL 245
++ + F L + ++ L
Sbjct: 399 LETLPGDVFGALPRLTEVLL 418
Score = 39.9 bits (89), Expect = 0.018
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 1/95 (1%)
Query: 106 SAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL 165
SA +G GL + L+L L L L +LR+++L L + FR L
Sbjct: 328 SALPQGAFQGLG-ELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNL 386
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHN 200
L + + H L T+ F AL +T ++L HN
Sbjct: 387 SSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHN 421
Score = 39.1 bits (87), Expect = 0.032
Identities = 30/134 (22%), Positives = 62/134 (46%), Gaps = 5/134 (3%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIR 250
N+T I+L ++S +F+G + + + ++ I + FS L + + L
Sbjct: 51 NLTHILLFGMGRGVLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKI 110
Query: 251 TIEPQAFAGLEGIGVLELAFMD---LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
T P A L+ + +LE F+D L + + F L+ + L+L ++ L + F
Sbjct: 111 THLPGAL--LDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTN 168
Query: 308 LQHVDTLEICNNKI 321
L+++ L++ N +
Sbjct: 169 LENLKLLDLSGNNL 182
Score = 34.3 bits (75), Expect = 0.90
Identities = 22/112 (19%), Positives = 55/112 (49%)
Query: 248 GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
G ++ Q+F+G+ + L ++ + ++ P TF LI++ L L + + + D
Sbjct: 61 GRGVLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDK 120
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI 359
+ ++ L + +N + GI++ + +++ L N + P ++ +EN+
Sbjct: 121 MVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENL 172
>L01131-1|AAA52301.1| 347|Homo sapiens decorin protein.
Length = 347
Score = 70.9 bits (166), Expect = 8e-12
Identities = 59/238 (24%), Positives = 98/238 (41%), Gaps = 10/238 (4%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L VP L P T L L + ++ F +L+ L L L ++++ P A
Sbjct: 65 VQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGA 124
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L LY+ L + LQ + + N I ++ F G N + +I L
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRA---HENEITKVRKVTFNGLNQMIVIEL 181
Query: 222 RNNPIKRILVH--AFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP+K + AF G+ + I + T PQ + L L + +
Sbjct: 182 GTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLP--PSLTELHLDGNKISRVDAA 239
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
+ GL + +L L + + + GS H+ L + NNK+ + L NN++ V
Sbjct: 240 SLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVVYL---HNNNISV 294
Score = 45.2 bits (102), Expect = 5e-04
Identities = 30/121 (24%), Positives = 62/121 (51%), Gaps = 6/121 (4%)
Query: 133 LRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLP-RLRELYIQHTPLATVDSFAFAALQN 191
+ + AF +++L + + N+T I +GLP L EL++ ++ VD+ + L N
Sbjct: 191 IENGAFQGMKKLSYIRIADTNITSIP----QGLPPSLTELHLDGNKISRVDAASLKGLNN 246
Query: 192 ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIR 250
+ + L+ N I+ +++ + A T + + L NN + R++ + ++ VG + P G
Sbjct: 247 LAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVVYLHNNNISVVGSSDFCPPGHN 306
Query: 251 T 251
T
Sbjct: 307 T 307
>J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA
encoding bone small proteoglycan I (biglycan), complete
cds. ).
Length = 368
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/236 (26%), Positives = 106/236 (44%), Gaps = 12/236 (5%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L+ VP +SP T L L D+ LR D F L+ L L L +++I A
Sbjct: 74 VQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L++LYI L + ++L + + NRI ++ F+G +N I +
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSL---VELRIHDNRIRKVPKGVFSGLRNMNCIEM 190
Query: 222 RNNPIKR--ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP++ AF GL + + + T P+ E + L L + ++ +
Sbjct: 191 GGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLP--ETLNELHLDHNKIQAIELE 247
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELSLVQ 331
++ RL L + + +I+ GS L + L + NNK+ G+ +L L+Q
Sbjct: 248 DLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQ 303
Score = 42.3 bits (95), Expect = 0.003
Identities = 21/77 (27%), Positives = 39/77 (50%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L+ +D+ ++ F GLQH+ L + NNKI I E + ++ ++ NH++E P
Sbjct: 95 LDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIP 154
Query: 350 EAVVLEVENIIIRGNHL 366
+ + + I N +
Sbjct: 155 PNLPSSLVELRIHDNRI 171
>BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/236 (26%), Positives = 106/236 (44%), Gaps = 12/236 (5%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L+ VP +SP T L L D+ LR D F L+ L L L +++I A
Sbjct: 74 VQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L++LYI L + ++L + + NRI ++ F+G +N I +
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSL---VELRIHDNRIRKVPKGVFSGLRNMNCIEM 190
Query: 222 RNNPIKR--ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP++ AF GL + + + T P+ E + L L + ++ +
Sbjct: 191 GGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLP--ETLNELHLDHNKIQAIELE 247
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELSLVQ 331
++ RL L + + +I+ GS L + L + NNK+ G+ +L L+Q
Sbjct: 248 DLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQ 303
Score = 42.3 bits (95), Expect = 0.003
Identities = 21/77 (27%), Positives = 39/77 (50%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L+ +D+ ++ F GLQH+ L + NNKI I E + ++ ++ NH++E P
Sbjct: 95 LDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIP 154
Query: 350 EAVVLEVENIIIRGNHL 366
+ + + I N +
Sbjct: 155 PNLPSSLVELRIHDNRI 171
>BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/236 (26%), Positives = 106/236 (44%), Gaps = 12/236 (5%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L+ VP +SP T L L D+ LR D F L+ L L L +++I A
Sbjct: 74 VQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L++LYI L + ++L + + NRI ++ F+G +N I +
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSL---VELRIHDNRIRKVPKGVFSGLRNMNCIEM 190
Query: 222 RNNPIKR--ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP++ AF GL + + + T P+ E + L L + ++ +
Sbjct: 191 GGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLP--ETLNELHLDHNKIQAIELE 247
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELSLVQ 331
++ RL L + + +I+ GS L + L + NNK+ G+ +L L+Q
Sbjct: 248 DLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQ 303
Score = 42.3 bits (95), Expect = 0.003
Identities = 21/77 (27%), Positives = 39/77 (50%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L+ +D+ ++ F GLQH+ L + NNKI I E + ++ ++ NH++E P
Sbjct: 95 LDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIP 154
Query: 350 EAVVLEVENIIIRGNHL 366
+ + + I N +
Sbjct: 155 PNLPSSLVELRIHDNRI 171
>BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/236 (26%), Positives = 106/236 (44%), Gaps = 12/236 (5%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L+ VP +SP T L L D+ LR D F L+ L L L +++I A
Sbjct: 74 VQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L++LYI L + ++L + + NRI ++ F+G +N I +
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSL---VELRIHDNRIRKVPKGVFSGLRNMNCIEM 190
Query: 222 RNNPIKR--ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP++ AF GL + + + T P+ E + L L + ++ +
Sbjct: 191 GGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLP--ETLNELHLDHNKIQAIELE 247
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELSLVQ 331
++ RL L + + +I+ GS L + L + NNK+ G+ +L L+Q
Sbjct: 248 DLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQ 303
Score = 42.3 bits (95), Expect = 0.003
Identities = 21/77 (27%), Positives = 39/77 (50%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L+ +D+ ++ F GLQH+ L + NNKI I E + ++ ++ NH++E P
Sbjct: 95 LDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIP 154
Query: 350 EAVVLEVENIIIRGNHL 366
+ + + I N +
Sbjct: 155 PNLPSSLVELRIHDNRI 171
>AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein
variant protein.
Length = 368
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/236 (26%), Positives = 106/236 (44%), Gaps = 12/236 (5%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L+ VP +SP T L L D+ LR D F L+ L L L +++I A
Sbjct: 74 VQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L++LYI L + ++L + + NRI ++ F+G +N I +
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSL---VELRIHDNRIRKVPKGVFSGLRNMNCIEM 190
Query: 222 RNNPIKR--ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP++ AF GL + + + T P+ E + L L + ++ +
Sbjct: 191 GGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLP--ETLNELHLDHNKIQAIELE 247
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELSLVQ 331
++ RL L + + +I+ GS L + L + NNK+ G+ +L L+Q
Sbjct: 248 DLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQ 303
Score = 42.3 bits (95), Expect = 0.003
Identities = 21/77 (27%), Positives = 39/77 (50%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L+ +D+ ++ F GLQH+ L + NNKI I E + ++ ++ NH++E P
Sbjct: 95 LDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIP 154
Query: 350 EAVVLEVENIIIRGNHL 366
+ + + I N +
Sbjct: 155 PNLPSSLVELRIHDNRI 171
>AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein
variant protein.
Length = 368
Score = 70.5 bits (165), Expect = 1e-11
Identities = 62/236 (26%), Positives = 106/236 (44%), Gaps = 12/236 (5%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L+ VP +SP T L L D+ LR D F L+ L L L +++I A
Sbjct: 74 VQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F L +L++LYI L + ++L + + NRI ++ F+G +N I +
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSL---VELRIHDNRIRKVPEGVFSGLRNMNCIEM 190
Query: 222 RNNPIKR--ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
NP++ AF GL + + + T P+ E + L L + ++ +
Sbjct: 191 GGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLP--ETLNELHLDHNKIQAIELE 247
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELSLVQ 331
++ RL L + + +I+ GS L + L + NNK+ G+ +L L+Q
Sbjct: 248 DLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQ 303
Score = 42.3 bits (95), Expect = 0.003
Identities = 21/77 (27%), Positives = 39/77 (50%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L+ +D+ ++ F GLQH+ L + NNKI I E + ++ ++ NH++E P
Sbjct: 95 LDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIP 154
Query: 350 EAVVLEVENIIIRGNHL 366
+ + + I N +
Sbjct: 155 PNLPSSLVELRIHDNRI 171
>BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat
neuronal 3 protein.
Length = 708
Score = 70.1 bits (164), Expect = 1e-11
Identities = 62/254 (24%), Positives = 113/254 (44%), Gaps = 6/254 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++T L LS+ +L + + + QL + L+ LT + L L+ELYI H L
Sbjct: 93 NLTSLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLL 152
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+T+ AF L N+ + L NR+ I S F + ++ + NPI RI F L
Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212
Query: 239 DVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + + + I A GLE + + L + ++ + L L ++ +
Sbjct: 213 NLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPI 272
Query: 298 GIIKVGSFDGLQHVDTLEICN-NKIDGIEELSLVQNNSVRVFKLTGNHMLE--SPEAV-- 352
I+ G F + H+ L I N ++ I+ L++ +R + T N L P A
Sbjct: 273 NRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFR 332
Query: 353 VLEVENIIIRGNHL 366
+ ++E++++ N L
Sbjct: 333 LPKLESLMLNSNAL 346
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 69.7 bits (163), Expect = 2e-11
Identities = 51/202 (25%), Positives = 97/202 (48%), Gaps = 4/202 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L + R + L AF L + L LD NLT I GL L+EL++ +
Sbjct: 240 ALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAI 299
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ A+ Q ++ + LT N +++++ +F G + +N + + NN + I AF GL+
Sbjct: 300 NRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLS 359
Query: 239 DVGQIELPSG--IRTIEPQ--AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
+ ++L + TIE AF+GL+ + L L + S+ F GL + L L +
Sbjct: 360 SLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSD 419
Query: 295 SDLGIIKVGSFDGLQHVDTLEI 316
+ + ++ +F ++ + L +
Sbjct: 420 NAIMSLQGNAFSQMKKLQQLHL 441
Score = 65.7 bits (153), Expect = 3e-10
Identities = 64/311 (20%), Positives = 134/311 (43%), Gaps = 11/311 (3%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G L+ ++ L L+R + + F L QL+ L L+ + + F+GL L+
Sbjct: 185 GYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKS 243
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L +Q + + AF L N+ + L HN + +I G + + L N I RI
Sbjct: 244 LKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRIS 303
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
A+ + +++L + + ++ +F GL + L + + + F GL +
Sbjct: 304 PDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKT 363
Query: 290 LSLRESDLGII---KVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHML 346
L L+ +++ G+F GL + L + N+I I + + +++ L+ N ++
Sbjct: 364 LDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIM 423
Query: 347 E---SPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALS--QDFAEENYCISPLKVRGRS 401
+ + + +++ + + + L C+C +A + Q F + C P ++GRS
Sbjct: 424 SLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNAS-CAHPQLLKGRS 482
Query: 402 LASATSGSAGC 412
+ + + C
Sbjct: 483 IFAVSPDGFVC 493
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 69.7 bits (163), Expect = 2e-11
Identities = 51/202 (25%), Positives = 97/202 (48%), Gaps = 4/202 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L + R + L AF L + L LD NLT I GL L+EL++ +
Sbjct: 240 ALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAI 299
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ A+ Q ++ + LT N +++++ +F G + +N + + NN + I AF GL+
Sbjct: 300 NRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLS 359
Query: 239 DVGQIELPSG--IRTIEPQ--AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
+ ++L + TIE AF+GL+ + L L + S+ F GL + L L +
Sbjct: 360 SLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSD 419
Query: 295 SDLGIIKVGSFDGLQHVDTLEI 316
+ + ++ +F ++ + L +
Sbjct: 420 NAIMSLQGNAFSQMKKLQQLHL 441
Score = 65.7 bits (153), Expect = 3e-10
Identities = 64/311 (20%), Positives = 134/311 (43%), Gaps = 11/311 (3%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G L+ ++ L L+R + + F L QL+ L L+ + + F+GL L+
Sbjct: 185 GYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKS 243
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L +Q + + AF L N+ + L HN + +I G + + L N I RI
Sbjct: 244 LKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRIS 303
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
A+ + +++L + + ++ +F GL + L + + + F GL +
Sbjct: 304 PDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKT 363
Query: 290 LSLRESDLGII---KVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHML 346
L L+ +++ G+F GL + L + N+I I + + +++ L+ N ++
Sbjct: 364 LDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIM 423
Query: 347 E---SPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALS--QDFAEENYCISPLKVRGRS 401
+ + + +++ + + + L C+C +A + Q F + C P ++GRS
Sbjct: 424 SLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNAS-CAHPQLLKGRS 482
Query: 402 LASATSGSAGC 412
+ + + C
Sbjct: 483 IFAVSPDGFVC 493
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 69.7 bits (163), Expect = 2e-11
Identities = 48/191 (25%), Positives = 92/191 (48%), Gaps = 4/191 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L + R + L+ AF L + L L+ NLTR+ GL L++LY+ +
Sbjct: 240 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAI 299
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ A+ Q ++ + L++N++ +++ AF G + + ++L +N + I F L+
Sbjct: 300 ERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLS 359
Query: 239 DVGQIELPSG--IRTIE--PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
++ ++L + IE +AFAGL + L L + S+ F GL + L L
Sbjct: 360 NLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNN 419
Query: 295 SDLGIIKVGSF 305
+ + I+ +F
Sbjct: 420 NAIMSIQENAF 430
Score = 68.1 bits (159), Expect = 6e-11
Identities = 60/266 (22%), Positives = 116/266 (43%), Gaps = 7/266 (2%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G LS S+ + L+R + ++ F L L+ L L + + F+GL LR
Sbjct: 185 GCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRS 243
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L +Q ++ + AF L N+ + L HN + ++ G + + + N I+RI
Sbjct: 244 LKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERIS 303
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
A+ + +++L + + ++ AF GL + L L + + F L +
Sbjct: 304 PDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQT 363
Query: 290 LSLRESDLG-IIKVGS--FDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHML 346
L LR +++ I+ S F GL + L + N+I I + + + S+ L N ++
Sbjct: 364 LDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIM 423
Query: 347 ESPEAVVLE--VENIIIRGNHLPCEC 370
E + ++ +I+ + L C+C
Sbjct: 424 SIQENAFSQTHLKELILNTSSLLCDC 449
Score = 44.4 bits (100), Expect = 8e-04
Identities = 51/194 (26%), Positives = 86/194 (44%), Gaps = 16/194 (8%)
Query: 168 LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIK 227
L+E+ + + L + F NIT + L HN I +I + A + + L +N I
Sbjct: 99 LQEVKMNYNELTEIPYFG-EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIIS 157
Query: 228 RILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIR 286
I +F + + + L + I T+E F L ++ + S++P L
Sbjct: 158 EIKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPH 216
Query: 287 VGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DG-------IEELSLVQNNSV 335
+ L L+ + + I++ +F GL + +L++ N I DG +EEL L NN
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 276
Query: 336 RVFK--LTGNHMLE 347
RV K L G ML+
Sbjct: 277 RVNKGWLYGLRMLQ 290
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 69.7 bits (163), Expect = 2e-11
Identities = 48/191 (25%), Positives = 92/191 (48%), Gaps = 4/191 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L + R + L+ AF L + L L+ NLTR+ GL L++LY+ +
Sbjct: 240 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAI 299
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ A+ Q ++ + L++N++ +++ AF G + + ++L +N + I F L+
Sbjct: 300 ERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLS 359
Query: 239 DVGQIELPSG--IRTIE--PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
++ ++L + IE +AFAGL + L L + S+ F GL + L L
Sbjct: 360 NLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNN 419
Query: 295 SDLGIIKVGSF 305
+ + I+ +F
Sbjct: 420 NAIMSIQENAF 430
Score = 68.1 bits (159), Expect = 6e-11
Identities = 60/266 (22%), Positives = 116/266 (43%), Gaps = 7/266 (2%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G LS S+ + L+R + ++ F L L+ L L + + F+GL LR
Sbjct: 185 GCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRS 243
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L +Q ++ + AF L N+ + L HN + ++ G + + + N I+RI
Sbjct: 244 LKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERIS 303
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
A+ + +++L + + ++ AF GL + L L + + F L +
Sbjct: 304 PDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQT 363
Query: 290 LSLRESDLG-IIKVGS--FDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHML 346
L LR +++ I+ S F GL + L + N+I I + + + S+ L N ++
Sbjct: 364 LDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIM 423
Query: 347 ESPEAVVLE--VENIIIRGNHLPCEC 370
E + ++ +I+ + L C+C
Sbjct: 424 SIQENAFSQTHLKELILNTSSLLCDC 449
Score = 44.4 bits (100), Expect = 8e-04
Identities = 51/194 (26%), Positives = 86/194 (44%), Gaps = 16/194 (8%)
Query: 168 LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIK 227
L+E+ + + L + F NIT + L HN I +I + A + + L +N I
Sbjct: 99 LQEVKMNYNELTEIPYFG-EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIIS 157
Query: 228 RILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIR 286
I +F + + + L + I T+E F L ++ + S++P L
Sbjct: 158 EIKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPH 216
Query: 287 VGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DG-------IEELSLVQNNSV 335
+ L L+ + + I++ +F GL + +L++ N I DG +EEL L NN
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 276
Query: 336 RVFK--LTGNHMLE 347
RV K L G ML+
Sbjct: 277 RVNKGWLYGLRMLQ 290
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 69.7 bits (163), Expect = 2e-11
Identities = 51/202 (25%), Positives = 97/202 (48%), Gaps = 4/202 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L + R + L AF L + L LD NLT I GL L+EL++ +
Sbjct: 240 ALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAI 299
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ A+ Q ++ + LT N +++++ +F G + +N + + NN + I AF GL+
Sbjct: 300 NRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLS 359
Query: 239 DVGQIELPSG--IRTIEPQ--AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
+ ++L + TIE AF+GL+ + L L + S+ F GL + L L +
Sbjct: 360 SLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSD 419
Query: 295 SDLGIIKVGSFDGLQHVDTLEI 316
+ + ++ +F ++ + L +
Sbjct: 420 NAIMSLQGNAFSQMKKLQQLHL 441
Score = 65.7 bits (153), Expect = 3e-10
Identities = 64/311 (20%), Positives = 134/311 (43%), Gaps = 11/311 (3%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G L+ ++ L L+R + + F L QL+ L L+ + + F+GL L+
Sbjct: 185 GYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKS 243
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L +Q + + AF L N+ + L HN + +I G + + L N I RI
Sbjct: 244 LKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRIS 303
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
A+ + +++L + + ++ +F GL + L + + + F GL +
Sbjct: 304 PDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKT 363
Query: 290 LSLRESDLGII---KVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHML 346
L L+ +++ G+F GL + L + N+I I + + +++ L+ N ++
Sbjct: 364 LDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIM 423
Query: 347 E---SPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALS--QDFAEENYCISPLKVRGRS 401
+ + + +++ + + + L C+C +A + Q F + C P ++GRS
Sbjct: 424 SLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNAS-CAHPQLLKGRS 482
Query: 402 LASATSGSAGC 412
+ + + C
Sbjct: 483 IFAVSPDGFVC 493
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 69.7 bits (163), Expect = 2e-11
Identities = 51/202 (25%), Positives = 97/202 (48%), Gaps = 4/202 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L + R + L AF L + L LD NLT I GL L+EL++ +
Sbjct: 180 ALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAI 239
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ A+ Q ++ + LT N +++++ +F G + +N + + NN + I AF GL+
Sbjct: 240 NRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLS 299
Query: 239 DVGQIELPSG--IRTIEPQ--AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
+ ++L + TIE AF+GL+ + L L + S+ F GL + L L +
Sbjct: 300 SLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSD 359
Query: 295 SDLGIIKVGSFDGLQHVDTLEI 316
+ + ++ +F ++ + L +
Sbjct: 360 NAIMSLQGNAFSQMKKLQQLHL 381
Score = 65.7 bits (153), Expect = 3e-10
Identities = 64/311 (20%), Positives = 134/311 (43%), Gaps = 11/311 (3%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G L+ ++ L L+R + + F L QL+ L L+ + + F+GL L+
Sbjct: 125 GYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKS 183
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L +Q + + AF L N+ + L HN + +I G + + L N I RI
Sbjct: 184 LKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRIS 243
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
A+ + +++L + + ++ +F GL + L + + + F GL +
Sbjct: 244 PDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKT 303
Query: 290 LSLRESDLGII---KVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHML 346
L L+ +++ G+F GL + L + N+I I + + +++ L+ N ++
Sbjct: 304 LDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIM 363
Query: 347 E---SPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALS--QDFAEENYCISPLKVRGRS 401
+ + + +++ + + + L C+C +A + Q F + C P ++GRS
Sbjct: 364 SLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNAS-CAHPQLLKGRS 422
Query: 402 LASATSGSAGC 412
+ + + C
Sbjct: 423 IFAVSPDGFVC 433
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 69.7 bits (163), Expect = 2e-11
Identities = 51/202 (25%), Positives = 97/202 (48%), Gaps = 4/202 (1%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L + R + L AF L + L LD NLT I GL L+EL++ +
Sbjct: 240 ALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAI 299
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ A+ Q ++ + LT N +++++ +F G + +N + + NN + I AF GL+
Sbjct: 300 NRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLS 359
Query: 239 DVGQIELPSG--IRTIEPQ--AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
+ ++L + TIE AF+GL+ + L L + S+ F GL + L L +
Sbjct: 360 SLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSD 419
Query: 295 SDLGIIKVGSFDGLQHVDTLEI 316
+ + ++ +F ++ + L +
Sbjct: 420 NAIMSLQGNAFSQMKKLQQLHL 441
Score = 65.7 bits (153), Expect = 3e-10
Identities = 64/311 (20%), Positives = 134/311 (43%), Gaps = 11/311 (3%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G L+ ++ L L+R + + F L QL+ L L+ + + F+GL L+
Sbjct: 185 GYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKS 243
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L +Q + + AF L N+ + L HN + +I G + + L N I RI
Sbjct: 244 LKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRIS 303
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
A+ + +++L + + ++ +F GL + L + + + F GL +
Sbjct: 304 PDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKT 363
Query: 290 LSLRESDLGII---KVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHML 346
L L+ +++ G+F GL + L + N+I I + + +++ L+ N ++
Sbjct: 364 LDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIM 423
Query: 347 E---SPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALS--QDFAEENYCISPLKVRGRS 401
+ + + +++ + + + L C+C +A + Q F + C P ++GRS
Sbjct: 424 SLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNAS-CAHPQLLKGRS 482
Query: 402 LASATSGSAGC 412
+ + + C
Sbjct: 483 IFAVSPDGFVC 493
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 69.7 bits (163), Expect = 2e-11
Identities = 48/191 (25%), Positives = 92/191 (48%), Gaps = 4/191 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L + R + L+ AF L + L L+ NLTR+ GL L++LY+ +
Sbjct: 240 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAI 299
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ A+ Q ++ + L++N++ +++ AF G + + ++L +N + I F L+
Sbjct: 300 ERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLS 359
Query: 239 DVGQIELPSG--IRTIE--PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
++ ++L + IE +AFAGL + L L + S+ F GL + L L
Sbjct: 360 NLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNN 419
Query: 295 SDLGIIKVGSF 305
+ + I+ +F
Sbjct: 420 NAIMSIQENAF 430
Score = 68.1 bits (159), Expect = 6e-11
Identities = 60/266 (22%), Positives = 116/266 (43%), Gaps = 7/266 (2%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G LS S+ + L+R + ++ F L L+ L L + + F+GL LR
Sbjct: 185 GCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRS 243
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L +Q ++ + AF L N+ + L HN + ++ G + + + N I+RI
Sbjct: 244 LKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERIS 303
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
A+ + +++L + + ++ AF GL + L L + + F L +
Sbjct: 304 PDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQT 363
Query: 290 LSLRESDLG-IIKVGS--FDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHML 346
L LR +++ I+ S F GL + L + N+I I + + + S+ L N ++
Sbjct: 364 LDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIM 423
Query: 347 ESPEAVVLE--VENIIIRGNHLPCEC 370
E + ++ +I+ + L C+C
Sbjct: 424 SIQENAFSQTHLKELILNTSSLLCDC 449
Score = 44.4 bits (100), Expect = 8e-04
Identities = 51/194 (26%), Positives = 86/194 (44%), Gaps = 16/194 (8%)
Query: 168 LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIK 227
L+E+ + + L + F NIT + L HN I +I + A + + L +N I
Sbjct: 99 LQEVKMNYNELTEIPYFG-EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIIS 157
Query: 228 RILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIR 286
I +F + + + L + I T+E F L ++ + S++P L
Sbjct: 158 EIKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPH 216
Query: 287 VGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DG-------IEELSLVQNNSV 335
+ L L+ + + I++ +F GL + +L++ N I DG +EEL L NN
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 276
Query: 336 RVFK--LTGNHMLE 347
RV K L G ML+
Sbjct: 277 RVNKGWLYGLRMLQ 290
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 69.7 bits (163), Expect = 2e-11
Identities = 48/191 (25%), Positives = 92/191 (48%), Gaps = 4/191 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L + R + L+ AF L + L L+ NLTR+ GL L++LY+ +
Sbjct: 248 SLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAI 307
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ A+ Q ++ + L++N++ +++ AF G + + ++L +N + I F L+
Sbjct: 308 ERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLS 367
Query: 239 DVGQIELPSG--IRTIE--PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRE 294
++ ++L + IE +AFAGL + L L + S+ F GL + L L
Sbjct: 368 NLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNN 427
Query: 295 SDLGIIKVGSF 305
+ + I+ +F
Sbjct: 428 NAIMSIQENAF 438
Score = 68.1 bits (159), Expect = 6e-11
Identities = 60/266 (22%), Positives = 116/266 (43%), Gaps = 7/266 (2%)
Query: 111 GVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
G LS S+ + L+R + ++ F L L+ L L + + F+GL LR
Sbjct: 193 GCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRS 251
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
L +Q ++ + AF L N+ + L HN + ++ G + + + N I+RI
Sbjct: 252 LKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERIS 311
Query: 231 VHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
A+ + +++L + + ++ AF GL + L L + + F L +
Sbjct: 312 PDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQT 371
Query: 290 LSLRESDLG-IIKVGS--FDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHML 346
L LR +++ I+ S F GL + L + N+I I + + + S+ L N ++
Sbjct: 372 LDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIM 431
Query: 347 ESPEAVVLE--VENIIIRGNHLPCEC 370
E + ++ +I+ + L C+C
Sbjct: 432 SIQENAFSQTHLKELILNTSSLLCDC 457
Score = 44.4 bits (100), Expect = 8e-04
Identities = 51/194 (26%), Positives = 86/194 (44%), Gaps = 16/194 (8%)
Query: 168 LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIK 227
L+E+ + + L + F NIT + L HN I +I + A + + L +N I
Sbjct: 107 LQEVKMNYNELTEIPYFG-EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLSSNIIS 165
Query: 228 RILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIR 286
I +F + + + L + I T+E F L ++ + S++P L
Sbjct: 166 EIKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPH 224
Query: 287 VGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DG-------IEELSLVQNNSV 335
+ L L+ + + I++ +F GL + +L++ N I DG +EEL L NN
Sbjct: 225 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 284
Query: 336 RVFK--LTGNHMLE 347
RV K L G ML+
Sbjct: 285 RVNKGWLYGLRMLQ 298
>J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precursor
protein.
Length = 545
Score = 69.3 bits (162), Expect = 3e-11
Identities = 55/202 (27%), Positives = 95/202 (47%), Gaps = 1/202 (0%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L LS L L F L L+ L LD+ N++ + P F L L L++Q +
Sbjct: 194 SLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAI 253
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ FA+L N+T + L N + + + FA T + +SL +N ++ + F+ L+
Sbjct: 254 THLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLS 313
Query: 239 DVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + L + I + F LE + L L +L +L P F L ++ LSL ++ L
Sbjct: 314 NLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQL 373
Query: 298 GIIKVGSFDGLQHVDTLEICNN 319
+ G FD ++ L + N
Sbjct: 374 TTLPEGIFDTNYNLFNLALHGN 395
Score = 54.4 bits (125), Expect = 8e-07
Identities = 49/227 (21%), Positives = 89/227 (39%), Gaps = 2/227 (0%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C Q +V C+ L VP + P + L + AF L ++ L
Sbjct: 28 CFVQ-EVFCSDEELATVPLDIPPYTKNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLC 86
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ RP AF GLPRL +L + + + + F+ L ++ + L N + + F
Sbjct: 87 QFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAA 146
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEP-QAFAGLEGIGVLELAFMDLP 274
+ + L+ N ++ + F L + + L + P + F L + L+L+ L
Sbjct: 147 LESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALS 206
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L F L + L L +++ + F L ++ L + N I
Sbjct: 207 GLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAI 253
Score = 50.4 bits (115), Expect = 1e-05
Identities = 37/121 (30%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 109 LRGVPSGL---SPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL 165
LR +P+GL +P + LSL+ L + FAHL LR L L +T + FR L
Sbjct: 277 LRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDL 336
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAF-AGTNFINLISLRNN 224
L +LY+ L + F L + + L+ N++ + F N NL +L N
Sbjct: 337 EELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNL-ALHGN 395
Query: 225 P 225
P
Sbjct: 396 P 396
Score = 37.1 bits (82), Expect = 0.13
Identities = 23/97 (23%), Positives = 43/97 (44%)
Query: 254 PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDT 313
P AF GL + LE+ +L + F L +G+L+L + L + G F L +++
Sbjct: 90 PDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALES 149
Query: 314 LEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
L + N++ + ++ L N + + PE
Sbjct: 150 LHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPE 186
>CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 69.3 bits (162), Expect = 3e-11
Identities = 62/254 (24%), Positives = 113/254 (44%), Gaps = 6/254 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++T L LS+ +L + + + QL + L+ LT + L L+ELYI H L
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLL 152
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+T+ AF L N+ + L NR+ I S F + ++ + NPI RI F L
Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212
Query: 239 DVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + + + I A GLE + + L + ++ + L L ++ +
Sbjct: 213 NLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPI 272
Query: 298 GIIKVGSFDGLQHVDTLEICN-NKIDGIEELSLVQNNSVRVFKLTGNHMLE--SPEAV-- 352
I+ G F + H+ L I N ++ I+ L++ +R + T N L P A
Sbjct: 273 NRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFR 332
Query: 353 VLEVENIIIRGNHL 366
+ ++E++++ N L
Sbjct: 333 LPKLESLMLNSNAL 346
>BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 69.3 bits (162), Expect = 3e-11
Identities = 55/202 (27%), Positives = 95/202 (47%), Gaps = 1/202 (0%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L LS L L F L L+ L LD+ N++ + P F L L L++Q +
Sbjct: 194 SLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAI 253
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ FA+L N+T + L N + + + FA T + +SL +N ++ + F+ L+
Sbjct: 254 THLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLS 313
Query: 239 DVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + L + I + F LE + L L +L +L P F L ++ LSL ++ L
Sbjct: 314 NLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQL 373
Query: 298 GIIKVGSFDGLQHVDTLEICNN 319
+ G FD ++ L + N
Sbjct: 374 TTLPEGIFDTNYNLFNLALHGN 395
Score = 54.0 bits (124), Expect = 1e-06
Identities = 49/227 (21%), Positives = 89/227 (39%), Gaps = 2/227 (0%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C Q +V C+ L VP + P + L + AF L ++ L
Sbjct: 28 CFVQ-EVFCSDEELATVPLDIPPYTKNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLC 86
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ RP AF GLPRL +L + + + + F+ L ++ + L N + + F
Sbjct: 87 QFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAA 146
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEP-QAFAGLEGIGVLELAFMDLP 274
+ + L+ N ++ + F L + + L + P + F L + L+L+ L
Sbjct: 147 LESLHLQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALS 206
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L F L + L L +++ + F L ++ L + N I
Sbjct: 207 GLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAI 253
Score = 50.4 bits (115), Expect = 1e-05
Identities = 37/121 (30%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 109 LRGVPSGL---SPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL 165
LR +P+GL +P + LSL+ L + FAHL LR L L +T + FR L
Sbjct: 277 LRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDL 336
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAF-AGTNFINLISLRNN 224
L +LY+ L + F L + + L+ N++ + F N NL +L N
Sbjct: 337 EELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNL-ALHGN 395
Query: 225 P 225
P
Sbjct: 396 P 396
Score = 37.5 bits (83), Expect = 0.097
Identities = 23/97 (23%), Positives = 43/97 (44%)
Query: 254 PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDT 313
P AF GL + LE+ +L + F L +G+L+L + L + G F L +++
Sbjct: 90 PDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALES 149
Query: 314 LEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
L + N++ + ++ L N + + PE
Sbjct: 150 LHLQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPE 186
>BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 69.3 bits (162), Expect = 3e-11
Identities = 55/202 (27%), Positives = 95/202 (47%), Gaps = 1/202 (0%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L LS L L F L L+ L LD+ N++ + P F L L L++Q +
Sbjct: 194 SLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAI 253
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ FA+L N+T + L N + + + FA T + +SL +N ++ + F+ L+
Sbjct: 254 THLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLS 313
Query: 239 DVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + L + I + F LE + L L +L +L P F L ++ LSL ++ L
Sbjct: 314 NLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQL 373
Query: 298 GIIKVGSFDGLQHVDTLEICNN 319
+ G FD ++ L + N
Sbjct: 374 TTLPEGIFDTNYNLFNLALHGN 395
Score = 54.4 bits (125), Expect = 8e-07
Identities = 49/227 (21%), Positives = 89/227 (39%), Gaps = 2/227 (0%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C Q +V C+ L VP + P + L + AF L ++ L
Sbjct: 28 CFVQ-EVFCSDEELATVPLDIPPYTKNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLC 86
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ RP AF GLPRL +L + + + + F+ L ++ + L N + + F
Sbjct: 87 QFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAA 146
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEP-QAFAGLEGIGVLELAFMDLP 274
+ + L+ N ++ + F L + + L + P + F L + L+L+ L
Sbjct: 147 LESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALS 206
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L F L + L L +++ + F L ++ L + N I
Sbjct: 207 GLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAI 253
Score = 50.4 bits (115), Expect = 1e-05
Identities = 37/121 (30%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 109 LRGVPSGL---SPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL 165
LR +P+GL +P + LSL+ L + FAHL LR L L +T + FR L
Sbjct: 277 LRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDL 336
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAF-AGTNFINLISLRNN 224
L +LY+ L + F L + + L+ N++ + F N NL +L N
Sbjct: 337 EELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNL-ALHGN 395
Query: 225 P 225
P
Sbjct: 396 P 396
Score = 37.1 bits (82), Expect = 0.13
Identities = 23/97 (23%), Positives = 43/97 (44%)
Query: 254 PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDT 313
P AF GL + LE+ +L + F L +G+L+L + L + G F L +++
Sbjct: 90 PDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALES 149
Query: 314 LEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
L + N++ + ++ L N + + PE
Sbjct: 150 LHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPE 186
>AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 69.3 bits (162), Expect = 3e-11
Identities = 62/254 (24%), Positives = 113/254 (44%), Gaps = 6/254 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++T L LS+ +L + + + QL + L+ LT + L L+ELYI H L
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLL 152
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+T+ AF L N+ + L NR+ I S F + ++ + NPI RI F L
Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212
Query: 239 DVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + + + I A GLE + + L + ++ + L L ++ +
Sbjct: 213 NLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPI 272
Query: 298 GIIKVGSFDGLQHVDTLEICN-NKIDGIEELSLVQNNSVRVFKLTGNHMLE--SPEAV-- 352
I+ G F + H+ L I N ++ I+ L++ +R + T N L P A
Sbjct: 273 NRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFR 332
Query: 353 VLEVENIIIRGNHL 366
+ ++E++++ N L
Sbjct: 333 LPKLESLMLNSNAL 346
>AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat
protein protein.
Length = 708
Score = 69.3 bits (162), Expect = 3e-11
Identities = 62/254 (24%), Positives = 113/254 (44%), Gaps = 6/254 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++T L LS+ +L + + + QL + L+ LT + L L+ELYI H L
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLL 152
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+T+ AF L N+ + L NR+ I S F + ++ + NPI RI F L
Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212
Query: 239 DVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + + + I A GLE + + L + ++ + L L ++ +
Sbjct: 213 NLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPI 272
Query: 298 GIIKVGSFDGLQHVDTLEICN-NKIDGIEELSLVQNNSVRVFKLTGNHMLE--SPEAV-- 352
I+ G F + H+ L I N ++ I+ L++ +R + T N L P A
Sbjct: 273 NRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFR 332
Query: 353 VLEVENIIIRGNHL 366
+ ++E++++ N L
Sbjct: 333 LPKLESLMLNSNAL 346
>AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich
repeat protein-3 protein.
Length = 708
Score = 69.3 bits (162), Expect = 3e-11
Identities = 62/254 (24%), Positives = 113/254 (44%), Gaps = 6/254 (2%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++T L LS+ +L + + + QL + L+ LT + L L+ELYI H L
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLL 152
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+T+ AF L N+ + L NR+ I S F + ++ + NPI RI F L
Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212
Query: 239 DVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
++ + + + I A GLE + + L + ++ + L L ++ +
Sbjct: 213 NLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPI 272
Query: 298 GIIKVGSFDGLQHVDTLEICN-NKIDGIEELSLVQNNSVRVFKLTGNHMLE--SPEAV-- 352
I+ G F + H+ L I N ++ I+ L++ +R + T N L P A
Sbjct: 273 NRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFR 332
Query: 353 VLEVENIIIRGNHL 366
+ ++E++++ N L
Sbjct: 333 LPKLESLMLNSNAL 346
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2
(Drosophila) protein.
Length = 1529
Score = 68.9 bits (161), Expect = 3e-11
Identities = 39/151 (25%), Positives = 76/151 (50%), Gaps = 1/151 (0%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C + +V C L +P+ L ++T++ L + ++V+ AF+ ++LRR+ L +
Sbjct: 277 CTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQI 336
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + P AF+GL L L + + + F L ++ ++L N+I + AF +
Sbjct: 337 SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLH 396
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+NL+SL +N ++ I FS L + + L
Sbjct: 397 NLNLLSLYDNKLQTIAKGTFSPLRAIQTMHL 427
Score = 62.5 bits (145), Expect = 3e-09
Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACNLTRIRPF 160
V C++ L +P + +L L+ + VL + F L QLR++ +T I
Sbjct: 517 VDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEG 576
Query: 161 AFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLIS 220
AF G + E+ + L V F L+++ +++L NRI + + +F G + + L+S
Sbjct: 577 AFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLS 636
Query: 221 LRNNPIKRILVHAFSGLNDVGQIEL 245
L +N I + AF L+ + + L
Sbjct: 637 LYDNQITTVAPGAFDTLHSLSTLNL 661
Score = 57.2 bits (132), Expect = 1e-07
Identities = 44/148 (29%), Positives = 63/148 (42%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S S V C+ ALR VP + + +L L+ ++ + FA LR LR L L ++ I
Sbjct: 35 SGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTI 94
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF+ L L L + L F + + L+ N+I I AF G I
Sbjct: 95 ERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIK 154
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L N I I AF L D+ + L
Sbjct: 155 NLQLDYNQISCIEDGAFRALRDLEVLTL 182
Score = 56.8 bits (131), Expect = 1e-07
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I I AF L ++ ++ L
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNH 114
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F G + L+L+ + ++ F G + + L L + + I+ G+F L
Sbjct: 115 LQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRAL 174
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I + S +R F+L N++
Sbjct: 175 RDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 52.4 bits (120), Expect = 3e-06
Identities = 33/125 (26%), Positives = 58/125 (46%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF L++L RL L+ +L F G +L L + + +
Sbjct: 84 LQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIP 143
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF +I ++ L +N+I+ IE AF + +++L NN I R+ V +F+ + +
Sbjct: 144 RKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRT 203
Query: 243 IELPS 247
L S
Sbjct: 204 FRLHS 208
Score = 51.2 bits (117), Expect = 7e-06
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 5/187 (2%)
Query: 190 QNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
Q + L +N +E+ F + I+ NN I I AF G + V +I L S
Sbjct: 533 QYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSN 592
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
+ ++ + F GLE + L L + + D+F GL V LSL ++ + + G+FD
Sbjct: 593 RLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDT 652
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV-VLEVENIIIRGNHL 366
L + TL + N + L+ + + +TGN + P + + ++++ I+
Sbjct: 653 LHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQ--DF 710
Query: 367 PCECGRD 373
C+ G D
Sbjct: 711 TCDDGND 717
Score = 49.2 bits (112), Expect = 3e-05
Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
I I L N IK I AFS + +I+L + I + P AF GL + L L +
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
L F GL + L L + + ++V +F L +++ L + +NK+ I + + +
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 335 VRVFKLTGN 343
++ L N
Sbjct: 422 IQTMHLAQN 430
Score = 46.8 bits (106), Expect = 2e-04
Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 1/108 (0%)
Query: 186 FAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
F L + I ++N+I IE AF G + +N I L +N ++ + F GL + + L
Sbjct: 554 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLML 613
Query: 246 PSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
S I + +F GL + +L L + ++ P F L + L+L
Sbjct: 614 RSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNL 661
Score = 44.4 bits (100), Expect = 8e-04
Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 2/115 (1%)
Query: 113 PSGLSP--SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
P SP + ++ LS + L DAF LR L L L +T + F GL L+
Sbjct: 317 PGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQL 376
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L + + + AF L N+ + L N++ I F+ I + L NP
Sbjct: 377 LLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNP 431
Score = 39.5 bits (88), Expect = 0.024
Identities = 23/104 (22%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R + L LD T + P L + + + ++T+ + +F+ + + +++L++NR
Sbjct: 754 RDVTELYLDGNQFTLV-PKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 812
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ I F G + L+SL N I + AF+ L+ + + +
Sbjct: 813 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAI 856
Score = 38.7 bits (86), Expect = 0.042
Identities = 22/108 (20%), Positives = 50/108 (46%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + +++ S + + AF + + L + L ++ F+GL L+ L ++
Sbjct: 558 PQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNR 617
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ V + +F L ++ + L N+I + AF + ++ ++L NP
Sbjct: 618 ITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANP 665
Score = 38.7 bits (86), Expect = 0.042
Identities = 22/73 (30%), Positives = 39/73 (53%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I T+ Q+F+ + + L L++ L + P TF GL + LSL +D+ ++ G+F+ L
Sbjct: 789 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL 848
Query: 309 QHVDTLEICNNKI 321
+ L I N +
Sbjct: 849 SALSHLAIGANPL 861
Score = 37.1 bits (82), Expect = 0.13
Identities = 32/167 (19%), Positives = 69/167 (41%), Gaps = 3/167 (1%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I+ I P AF+ + + ++L+ + L PD F GL + L L + + + F+GL
Sbjct: 312 IKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGL 371
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM---LESPEAVVLEVENIIIRGNH 365
+ L + NKI+ + + +++ + L N + + + + ++ + + N
Sbjct: 372 FSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNP 431
Query: 366 LPCECGRDPFTNPLALSQDFAEENYCISPLKVRGRSLASATSGSAGC 412
C+C + L + C SP ++ + + S C
Sbjct: 432 FICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRC 478
Score = 37.1 bits (82), Expect = 0.13
Identities = 26/131 (19%), Positives = 62/131 (47%), Gaps = 2/131 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
CL + V C++ L+ +P G+ VT+L L ++ + ++ + L + L ++
Sbjct: 733 CLD-TVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRIS 790
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ +F + +L L + + L + F L+++ + L N I+ + AF +
Sbjct: 791 TLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 850
Query: 216 INLISLRNNPI 226
++ +++ NP+
Sbjct: 851 LSHLAIGANPL 861
Score = 35.5 bits (78), Expect = 0.39
Identities = 20/66 (30%), Positives = 32/66 (48%)
Query: 289 RLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLES 348
RL L +++ I F GL+H+ L++ NKI IE + + +L NH+
Sbjct: 59 RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLF 118
Query: 349 PEAVVL 354
PE + L
Sbjct: 119 PELLFL 124
Score = 35.5 bits (78), Expect = 0.39
Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
+G+PR + ELY+ V + +++T I L++NRI+ + + +F+ + + L
Sbjct: 750 KGIPRDVTELYLDGNQFTLVPK-ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLIL 808
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ-AFAGLEGIGVLEL 268
N ++ I F GL + + L ++ P+ AF L + L +
Sbjct: 809 SYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAI 856
Score = 31.9 bits (69), Expect = 4.8
Identities = 19/100 (19%), Positives = 50/100 (50%), Gaps = 9/100 (9%)
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
++P+ LP+T + + L ++ + +I G+F + + +++ NN+I + +
Sbjct: 293 EIPTNLPET------ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQG 346
Query: 332 NNSVRVFKLTGNHMLESPEAV---VLEVENIIIRGNHLPC 368
S+ L GN + E P+++ + ++ +++ N + C
Sbjct: 347 LRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINC 386
Score = 31.5 bits (68), Expect = 6.4
Identities = 16/50 (32%), Positives = 25/50 (50%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+ L L + + AF LR L L L+ N+TR+ +F +P+LR
Sbjct: 153 IKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLR 202
>AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein.
Length = 798
Score = 68.9 bits (161), Expect = 3e-11
Identities = 41/152 (26%), Positives = 76/152 (50%), Gaps = 2/152 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C ++ VV C+S L +P + S +L L+ ++ +L + F L L+++ L
Sbjct: 510 CRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNK 569
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
++ I AF G + EL++ L ++ S F L + +++L +NRI+ I + +F G
Sbjct: 570 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 629
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L+SL +N I + AF L + + L
Sbjct: 630 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 661
Score = 64.9 bits (151), Expect = 6e-10
Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 1/157 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R RL L+ N+TRI F GL +LR L + + V+ AF ++ + + L N+
Sbjct: 44 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 103
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL 260
+ + F ++ + L N I+ I AF G D+ ++L I IE AF L
Sbjct: 104 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 163
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
G+ VL L ++ ++ +F+ + ++ L + L
Sbjct: 164 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 60.9 bits (141), Expect = 9e-09
Identities = 44/163 (26%), Positives = 79/163 (48%), Gaps = 2/163 (1%)
Query: 190 QNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
Q+ + L +N I+ +E+ F + I+L NN + I AF G V ++ L +
Sbjct: 533 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 592
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
+ +I F GL+G+ L L + + D+F GL V LSL ++ + + G+FD
Sbjct: 593 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 652
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
LQ + TL + N + +L+ + + +TGN ++P+
Sbjct: 653 LQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPD 695
Score = 56.0 bits (129), Expect = 3e-07
Identities = 40/162 (24%), Positives = 74/162 (45%), Gaps = 11/162 (6%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLA-LDAC 152
+C + +V C L +P+ L ++T++ L ++ + AF+ R+LRR+ L C
Sbjct: 268 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIRPLSFC 327
Query: 153 N---------LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
+ + I P AF+GL L L + + + F L + ++L N+I
Sbjct: 328 SPCRDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKIN 387
Query: 204 QIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
I AF ++L+SL +N I+ + F+ L + + L
Sbjct: 388 CIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHL 429
Score = 54.8 bits (126), Expect = 6e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I + AF + ++ ++ L
Sbjct: 44 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 103
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + + L+L+ + ++ F G + L L ++ + I+ G+F L
Sbjct: 104 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 163
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R F+L NH+
Sbjct: 164 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 54.4 bits (125), Expect = 8e-07
Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI + F+GL + ++L I +E AF ++ + L L L L
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F + RL L E+ + I +F G + L++ N+I IEE + + V
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 168
Query: 338 FKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ P + + ++ + NHL C+C + L C P
Sbjct: 169 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGP 228
Query: 395 LKVRGRSLASATSGSAGCRGE 415
+RG ++A C G+
Sbjct: 229 ASLRGLNVAEVQKSEFSCSGQ 249
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/104 (26%), Positives = 51/104 (49%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+++LS + + AF + L L A L IR FRGL LR L +++ ++ +
Sbjct: 562 KINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCI 621
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ +F L+N+ + L N+I + AF ++ ++L NP
Sbjct: 622 HNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 665
Score = 45.2 bits (102), Expect = 5e-04
Identities = 30/125 (24%), Positives = 55/125 (44%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF +++L RL L+ L + F+ L L + + +
Sbjct: 73 LQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP 132
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF ++ ++ L N+I+ IE AF + +++L NN I I V +F+ + +
Sbjct: 133 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 192
Query: 243 IELPS 247
L S
Sbjct: 193 FRLHS 197
Score = 44.8 bits (101), Expect = 6e-04
Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
Query: 221 LRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ-AFAGLEGIGVLELAFMDLPSLLPD 279
L NN I I AF GL + + L T P+ F GL + +L L + + PD
Sbjct: 333 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 392
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNN 319
F L + LSL ++ + + G+F L+ + TL + N
Sbjct: 393 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 43.6 bits (98), Expect = 0.001
Identities = 29/101 (28%), Positives = 43/101 (42%)
Query: 125 LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSF 184
LS + + DAF LR L L L +T + F GL L+ L + + +
Sbjct: 333 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 392
Query: 185 AFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
AF LQN++ + L N+I + F I + L NP
Sbjct: 393 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNP 433
Score = 40.3 bits (90), Expect = 0.014
Identities = 25/95 (26%), Positives = 42/95 (44%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I I P AF GL + L L + L F GL + L L + + I+ +F L
Sbjct: 338 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 397
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
Q++ L + +NKI + + + +++ L N
Sbjct: 398 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 40.3 bits (90), Expect = 0.014
Identities = 27/82 (32%), Positives = 42/82 (51%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
SV++L L+ L +RS F L LR L L ++ I +F GL +R L + +
Sbjct: 583 SVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 642
Query: 179 ATVDSFAFAALQNITSIVLTHN 200
TV AF LQ+++++ L N
Sbjct: 643 TTVSPGAFDTLQSLSTLNLLAN 664
Score = 31.1 bits (67), Expect = 8.4
Identities = 28/149 (18%), Positives = 57/149 (38%), Gaps = 3/149 (2%)
Query: 267 ELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
+L+ + + PD F GL + L L + + + G F GL + L + NKI+ I
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 327 LSLVQNNSVRVFKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQ 383
+ ++ + L N + + + ++ + + N C+C + L +
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNP 451
Query: 384 DFAEENYCISPLKVRGRSLASATSGSAGC 412
C SP ++ + + S C
Sbjct: 452 IETSGARCASPRRLANKRIGQIKSKKFRC 480
>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 68.9 bits (161), Expect = 3e-11
Identities = 41/152 (26%), Positives = 76/152 (50%), Gaps = 2/152 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C ++ VV C+S L +P + S +L L+ ++ +L + F L L+++ L
Sbjct: 517 CRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNK 576
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
++ I AF G + EL++ L ++ S F L + +++L +NRI+ I + +F G
Sbjct: 577 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 636
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L+SL +N I + AF L + + L
Sbjct: 637 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 668
Score = 65.7 bits (153), Expect = 3e-10
Identities = 39/152 (25%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +V C L +P+ L ++T++ L ++ + AF+ R+LRR+ L
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQ 344
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ I P AF+GL L L + + + F L + ++L N+I I AF
Sbjct: 345 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 404
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
++L+SL +N I+ + F+ L + + L
Sbjct: 405 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHL 436
Score = 64.9 bits (151), Expect = 6e-10
Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 1/157 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R RL L+ N+TRI F GL +LR L + + V+ AF ++ + + L N+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL 260
+ + F ++ + L N I+ I AF G D+ ++L I IE AF L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
G+ VL L ++ ++ +F+ + ++ L + L
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 60.9 bits (141), Expect = 9e-09
Identities = 44/163 (26%), Positives = 79/163 (48%), Gaps = 2/163 (1%)
Query: 190 QNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
Q+ + L +N I+ +E+ F + I+L NN + I AF G V ++ L +
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
+ +I F GL+G+ L L + + D+F GL V LSL ++ + + G+FD
Sbjct: 600 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 659
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
LQ + TL + N + +L+ + + +TGN ++P+
Sbjct: 660 LQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPD 702
Score = 54.8 bits (126), Expect = 6e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I + AF + ++ ++ L
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + + L+L+ + ++ F G + L L ++ + I+ G+F L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R F+L NH+
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 54.4 bits (125), Expect = 8e-07
Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI + F+GL + ++L I +E AF ++ + L L L L
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F + RL L E+ + I +F G + L++ N+I IEE + + V
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 338 FKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ P + + ++ + NHL C+C + L C P
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGP 245
Query: 395 LKVRGRSLASATSGSAGCRGE 415
+RG ++A C G+
Sbjct: 246 ASLRGLNVAEVQKSEFSCSGQ 266
Score = 54.0 bits (124), Expect = 1e-06
Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+ +T I L N I I AF+ + I L NN I I AF GL + + L
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368
Query: 250 RTIEPQ-AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
T P+ F GL + +L L + + PD F L + LSL ++ + + G+F L
Sbjct: 369 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 428
Query: 309 QHVDTLEICNN 319
+ + TL + N
Sbjct: 429 RAIQTLHLAQN 439
Score = 49.2 bits (112), Expect = 3e-05
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 1/126 (0%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
I L N IK I AFS + +I+L + I I P AF GL + L L + L
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F GL + L L + + I+ +F LQ++ L + +NKI + + + +++
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQT 433
Query: 338 FKLTGN 343
L N
Sbjct: 434 LHLAQN 439
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Query: 109 LRGVPSG-LSP--SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL 165
++ +P G SP + ++ LS + + DAF LR L L L +T + F GL
Sbjct: 321 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 380
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L+ L + + + AF LQN++ + L N+I + F I + L NP
Sbjct: 381 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNP 440
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/104 (26%), Positives = 51/104 (49%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+++LS + + AF + L L A L IR FRGL LR L +++ ++ +
Sbjct: 569 KINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCI 628
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ +F L+N+ + L N+I + AF ++ ++L NP
Sbjct: 629 HNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672
Score = 45.2 bits (102), Expect = 5e-04
Identities = 30/125 (24%), Positives = 55/125 (44%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF +++L RL L+ L + F+ L L + + +
Sbjct: 90 LQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP 149
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF ++ ++ L N+I+ IE AF + +++L NN I I V +F+ + +
Sbjct: 150 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 209
Query: 243 IELPS 247
L S
Sbjct: 210 FRLHS 214
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/131 (21%), Positives = 63/131 (48%), Gaps = 2/131 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
CL + V C++ LR +P G+ +VT+L L ++ + + L+ + L ++
Sbjct: 740 CLD-TVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKIS 797
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ +F + +L L + + L + AF L+++ + L N I+ ++ FA
Sbjct: 798 SLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTS 857
Query: 216 INLISLRNNPI 226
++ +++ NP+
Sbjct: 858 LSHLAIGANPL 868
Score = 40.3 bits (90), Expect = 0.014
Identities = 27/82 (32%), Positives = 42/82 (51%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
SV++L L+ L +RS F L LR L L ++ I +F GL +R L + +
Sbjct: 590 SVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 649
Query: 179 ATVDSFAFAALQNITSIVLTHN 200
TV AF LQ+++++ L N
Sbjct: 650 TTVSPGAFDTLQSLSTLNLLAN 671
Score = 32.3 bits (70), Expect = 3.6
Identities = 23/108 (21%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
+G+P+ + ELY+ V + + + + L++N+I+ + + +F + + + L
Sbjct: 757 KGIPKNVTELYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLIL 815
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
N ++ I AF GL + + L + I T++ FA + + L +
Sbjct: 816 SYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAI 863
>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 68.9 bits (161), Expect = 3e-11
Identities = 41/152 (26%), Positives = 76/152 (50%), Gaps = 2/152 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C ++ VV C+S L +P + S +L L+ ++ +L + F L L+++ L
Sbjct: 517 CRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNK 576
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
++ I AF G + EL++ L ++ S F L + +++L +NRI+ I + +F G
Sbjct: 577 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 636
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L+SL +N I + AF L + + L
Sbjct: 637 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 668
Score = 65.7 bits (153), Expect = 3e-10
Identities = 39/152 (25%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +V C L +P+ L ++T++ L ++ + AF+ R+LRR+ L
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQ 344
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ I P AF+GL L L + + + F L + ++L N+I I AF
Sbjct: 345 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 404
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
++L+SL +N I+ + F+ L + + L
Sbjct: 405 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHL 436
Score = 64.9 bits (151), Expect = 6e-10
Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 1/157 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R RL L+ N+TRI F GL +LR L + + V+ AF ++ + + L N+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL 260
+ + F ++ + L N I+ I AF G D+ ++L I IE AF L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
G+ VL L ++ ++ +F+ + ++ L + L
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 60.9 bits (141), Expect = 9e-09
Identities = 44/163 (26%), Positives = 79/163 (48%), Gaps = 2/163 (1%)
Query: 190 QNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
Q+ + L +N I+ +E+ F + I+L NN + I AF G V ++ L +
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
+ +I F GL+G+ L L + + D+F GL V LSL ++ + + G+FD
Sbjct: 600 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 659
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
LQ + TL + N + +L+ + + +TGN ++P+
Sbjct: 660 LQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPD 702
Score = 54.8 bits (126), Expect = 6e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I + AF + ++ ++ L
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + + L+L+ + ++ F G + L L ++ + I+ G+F L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R F+L NH+
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 54.4 bits (125), Expect = 8e-07
Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI + F+GL + ++L I +E AF ++ + L L L L
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F + RL L E+ + I +F G + L++ N+I IEE + + V
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 338 FKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ P + + ++ + NHL C+C + L C P
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGP 245
Query: 395 LKVRGRSLASATSGSAGCRGE 415
+RG ++A C G+
Sbjct: 246 ASLRGLNVAEVQKSEFSCSGQ 266
Score = 54.0 bits (124), Expect = 1e-06
Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+ +T I L N I I AF+ + I L NN I I AF GL + + L
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368
Query: 250 RTIEPQ-AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
T P+ F GL + +L L + + PD F L + LSL ++ + + G+F L
Sbjct: 369 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 428
Query: 309 QHVDTLEICNN 319
+ + TL + N
Sbjct: 429 RAIQTLHLAQN 439
Score = 49.2 bits (112), Expect = 3e-05
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 1/126 (0%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
I L N IK I AFS + +I+L + I I P AF GL + L L + L
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F GL + L L + + I+ +F LQ++ L + +NKI + + + +++
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQT 433
Query: 338 FKLTGN 343
L N
Sbjct: 434 LHLAQN 439
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Query: 109 LRGVPSG-LSP--SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL 165
++ +P G SP + ++ LS + + DAF LR L L L +T + F GL
Sbjct: 321 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 380
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L+ L + + + AF LQN++ + L N+I + F I + L NP
Sbjct: 381 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNP 440
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/104 (26%), Positives = 51/104 (49%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+++LS + + AF + L L A L IR FRGL LR L +++ ++ +
Sbjct: 569 KINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCI 628
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ +F L+N+ + L N+I + AF ++ ++L NP
Sbjct: 629 HNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672
Score = 45.2 bits (102), Expect = 5e-04
Identities = 30/125 (24%), Positives = 55/125 (44%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF +++L RL L+ L + F+ L L + + +
Sbjct: 90 LQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP 149
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF ++ ++ L N+I+ IE AF + +++L NN I I V +F+ + +
Sbjct: 150 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 209
Query: 243 IELPS 247
L S
Sbjct: 210 FRLHS 214
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/131 (21%), Positives = 63/131 (48%), Gaps = 2/131 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
CL + V C++ LR +P G+ +VT+L L ++ + + L+ + L ++
Sbjct: 740 CLD-TVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKIS 797
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ +F + +L L + + L + AF L+++ + L N I+ ++ FA
Sbjct: 798 SLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTS 857
Query: 216 INLISLRNNPI 226
++ +++ NP+
Sbjct: 858 LSHLAIGANPL 868
Score = 40.3 bits (90), Expect = 0.014
Identities = 27/82 (32%), Positives = 42/82 (51%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
SV++L L+ L +RS F L LR L L ++ I +F GL +R L + +
Sbjct: 590 SVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 649
Query: 179 ATVDSFAFAALQNITSIVLTHN 200
TV AF LQ+++++ L N
Sbjct: 650 TTVSPGAFDTLQSLSTLNLLAN 671
Score = 32.3 bits (70), Expect = 3.6
Identities = 23/108 (21%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
+G+P+ + ELY+ V + + + + L++N+I+ + + +F + + + L
Sbjct: 757 KGIPKNVTELYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLIL 815
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
N ++ I AF GL + + L + I T++ FA + + L +
Sbjct: 816 SYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAI 863
>AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 782
Score = 68.9 bits (161), Expect = 3e-11
Identities = 41/152 (26%), Positives = 76/152 (50%), Gaps = 2/152 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C ++ VV C+S L +P + S +L L+ ++ +L + F L L+++ L
Sbjct: 510 CRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNK 569
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
++ I AF G + EL++ L ++ S F L + +++L +NRI+ I + +F G
Sbjct: 570 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 629
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L+SL +N I + AF L + + L
Sbjct: 630 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 661
Score = 64.9 bits (151), Expect = 6e-10
Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 1/157 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R RL L+ N+TRI F GL +LR L + + V+ AF ++ + + L N+
Sbjct: 44 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 103
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL 260
+ + F ++ + L N I+ I AF G D+ ++L I IE AF L
Sbjct: 104 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 163
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
G+ VL L ++ ++ +F+ + ++ L + L
Sbjct: 164 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 60.9 bits (141), Expect = 9e-09
Identities = 44/163 (26%), Positives = 79/163 (48%), Gaps = 2/163 (1%)
Query: 190 QNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
Q+ + L +N I+ +E+ F + I+L NN + I AF G V ++ L +
Sbjct: 533 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 592
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
+ +I F GL+G+ L L + + D+F GL V LSL ++ + + G+FD
Sbjct: 593 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 652
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
LQ + TL + N + +L+ + + +TGN ++P+
Sbjct: 653 LQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPD 695
Score = 56.4 bits (130), Expect = 2e-07
Identities = 40/162 (24%), Positives = 74/162 (45%), Gaps = 11/162 (6%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLA-LDAC 152
+C + +V C L +P+ L ++T++ L ++ + AF+ R+LRR+ L C
Sbjct: 268 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRICPLSFC 327
Query: 153 N---------LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
+ + I P AF+GL L L + + + F L + ++L N+I
Sbjct: 328 SPCRDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKIN 387
Query: 204 QIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
I AF ++L+SL +N I+ + F+ L + + L
Sbjct: 388 CIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHL 429
Score = 54.8 bits (126), Expect = 6e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I + AF + ++ ++ L
Sbjct: 44 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 103
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + + L+L+ + ++ F G + L L ++ + I+ G+F L
Sbjct: 104 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 163
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R F+L NH+
Sbjct: 164 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 54.4 bits (125), Expect = 8e-07
Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI + F+GL + ++L I +E AF ++ + L L L L
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F + RL L E+ + I +F G + L++ N+I IEE + + V
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 168
Query: 338 FKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ P + + ++ + NHL C+C + L C P
Sbjct: 169 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGP 228
Query: 395 LKVRGRSLASATSGSAGCRGE 415
+RG ++A C G+
Sbjct: 229 ASLRGLNVAEVQKSEFSCSGQ 249
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/104 (26%), Positives = 51/104 (49%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+++LS + + AF + L L A L IR FRGL LR L +++ ++ +
Sbjct: 562 KINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCI 621
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ +F L+N+ + L N+I + AF ++ ++L NP
Sbjct: 622 HNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 665
Score = 45.2 bits (102), Expect = 5e-04
Identities = 30/125 (24%), Positives = 55/125 (44%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF +++L RL L+ L + F+ L L + + +
Sbjct: 73 LQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP 132
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF ++ ++ L N+I+ IE AF + +++L NN I I V +F+ + +
Sbjct: 133 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 192
Query: 243 IELPS 247
L S
Sbjct: 193 FRLHS 197
Score = 44.8 bits (101), Expect = 6e-04
Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
Query: 221 LRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ-AFAGLEGIGVLELAFMDLPSLLPD 279
L NN I I AF GL + + L T P+ F GL + +L L + + PD
Sbjct: 333 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 392
Query: 280 TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNN 319
F L + LSL ++ + + G+F L+ + TL + N
Sbjct: 393 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 43.6 bits (98), Expect = 0.001
Identities = 29/101 (28%), Positives = 43/101 (42%)
Query: 125 LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSF 184
LS + + DAF LR L L L +T + F GL L+ L + + +
Sbjct: 333 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 392
Query: 185 AFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
AF LQN++ + L N+I + F I + L NP
Sbjct: 393 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNP 433
Score = 40.3 bits (90), Expect = 0.014
Identities = 25/95 (26%), Positives = 42/95 (44%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I I P AF GL + L L + L F GL + L L + + I+ +F L
Sbjct: 338 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 397
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
Q++ L + +NKI + + + +++ L N
Sbjct: 398 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 40.3 bits (90), Expect = 0.014
Identities = 27/82 (32%), Positives = 42/82 (51%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
SV++L L+ L +RS F L LR L L ++ I +F GL +R L + +
Sbjct: 583 SVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 642
Query: 179 ATVDSFAFAALQNITSIVLTHN 200
TV AF LQ+++++ L N
Sbjct: 643 TTVSPGAFDTLQSLSTLNLLAN 664
Score = 31.1 bits (67), Expect = 8.4
Identities = 28/149 (18%), Positives = 57/149 (38%), Gaps = 3/149 (2%)
Query: 267 ELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
+L+ + + PD F GL + L L + + + G F GL + L + NKI+ I
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 327 LSLVQNNSVRVFKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQ 383
+ ++ + L N + + + ++ + + N C+C + L +
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNP 451
Query: 384 DFAEENYCISPLKVRGRSLASATSGSAGC 412
C SP ++ + + S C
Sbjct: 452 IETSGARCASPRRLANKRIGQIKSKKFRC 480
>AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 68.9 bits (161), Expect = 3e-11
Identities = 41/152 (26%), Positives = 76/152 (50%), Gaps = 2/152 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C ++ VV C+S L +P + S +L L+ ++ +L + F L L+++ L
Sbjct: 517 CRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNK 576
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
++ I AF G + EL++ L ++ S F L + +++L +NRI+ I + +F G
Sbjct: 577 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 636
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L+SL +N I + AF L + + L
Sbjct: 637 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 668
Score = 65.7 bits (153), Expect = 3e-10
Identities = 39/152 (25%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +V C L +P+ L ++T++ L ++ + AF+ R+LRR+ L
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQ 344
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ I P AF+GL L L + + + F L + ++L N+I I AF
Sbjct: 345 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 404
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
++L+SL +N I+ + F+ L + + L
Sbjct: 405 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHL 436
Score = 64.9 bits (151), Expect = 6e-10
Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 1/157 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R RL L+ N+TRI F GL +LR L + + V+ AF ++ + + L N+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL 260
+ + F ++ + L N I+ I AF G D+ ++L I IE AF L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
G+ VL L ++ ++ +F+ + ++ L + L
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 60.9 bits (141), Expect = 9e-09
Identities = 44/163 (26%), Positives = 79/163 (48%), Gaps = 2/163 (1%)
Query: 190 QNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
Q+ + L +N I+ +E+ F + I+L NN + I AF G V ++ L +
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
+ +I F GL+G+ L L + + D+F GL V LSL ++ + + G+FD
Sbjct: 600 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 659
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
LQ + TL + N + +L+ + + +TGN ++P+
Sbjct: 660 LQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPD 702
Score = 54.8 bits (126), Expect = 6e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I + AF + ++ ++ L
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + + L+L+ + ++ F G + L L ++ + I+ G+F L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R F+L NH+
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 54.4 bits (125), Expect = 8e-07
Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI + F+GL + ++L I +E AF ++ + L L L L
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F + RL L E+ + I +F G + L++ N+I IEE + + V
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 338 FKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ P + + ++ + NHL C+C + L C P
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGP 245
Query: 395 LKVRGRSLASATSGSAGCRGE 415
+RG ++A C G+
Sbjct: 246 ASLRGLNVAEVQKSEFSCSGQ 266
Score = 54.0 bits (124), Expect = 1e-06
Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+ +T I L N I I AF+ + I L NN I I AF GL + + L
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368
Query: 250 RTIEPQ-AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
T P+ F GL + +L L + + PD F L + LSL ++ + + G+F L
Sbjct: 369 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 428
Query: 309 QHVDTLEICNN 319
+ + TL + N
Sbjct: 429 RAIQTLHLAQN 439
Score = 49.2 bits (112), Expect = 3e-05
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 1/126 (0%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
I L N IK I AFS + +I+L + I I P AF GL + L L + L
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F GL + L L + + I+ +F LQ++ L + +NKI + + + +++
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQT 433
Query: 338 FKLTGN 343
L N
Sbjct: 434 LHLAQN 439
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Query: 109 LRGVPSG-LSP--SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL 165
++ +P G SP + ++ LS + + DAF LR L L L +T + F GL
Sbjct: 321 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 380
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L+ L + + + AF LQN++ + L N+I + F I + L NP
Sbjct: 381 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNP 440
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/104 (26%), Positives = 51/104 (49%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+++LS + + AF + L L A L IR FRGL LR L +++ ++ +
Sbjct: 569 KINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCI 628
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ +F L+N+ + L N+I + AF ++ ++L NP
Sbjct: 629 HNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672
Score = 45.2 bits (102), Expect = 5e-04
Identities = 30/125 (24%), Positives = 55/125 (44%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF +++L RL L+ L + F+ L L + + +
Sbjct: 90 LQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP 149
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF ++ ++ L N+I+ IE AF + +++L NN I I V +F+ + +
Sbjct: 150 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 209
Query: 243 IELPS 247
L S
Sbjct: 210 FRLHS 214
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/131 (21%), Positives = 63/131 (48%), Gaps = 2/131 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
CL + V C++ LR +P G+ +VT+L L ++ + + L+ + L ++
Sbjct: 740 CLD-TVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKIS 797
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ +F + +L L + + L + AF L+++ + L N I+ ++ FA
Sbjct: 798 SLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTS 857
Query: 216 INLISLRNNPI 226
++ +++ NP+
Sbjct: 858 LSHLAIGANPL 868
Score = 40.3 bits (90), Expect = 0.014
Identities = 27/82 (32%), Positives = 42/82 (51%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
SV++L L+ L +RS F L LR L L ++ I +F GL +R L + +
Sbjct: 590 SVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 649
Query: 179 ATVDSFAFAALQNITSIVLTHN 200
TV AF LQ+++++ L N
Sbjct: 650 TTVSPGAFDTLQSLSTLNLLAN 671
Score = 32.3 bits (70), Expect = 3.6
Identities = 23/108 (21%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
+G+P+ + ELY+ V + + + + L++N+I+ + + +F + + + L
Sbjct: 757 KGIPKNVTELYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLIL 815
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
N ++ I AF GL + + L + I T++ FA + + L +
Sbjct: 816 SYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAI 863
>AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 68.9 bits (161), Expect = 3e-11
Identities = 41/152 (26%), Positives = 76/152 (50%), Gaps = 2/152 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C ++ VV C+S L +P + S +L L+ ++ +L + F L L+++ L
Sbjct: 517 CRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNK 576
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
++ I AF G + EL++ L ++ S F L + +++L +NRI+ I + +F G
Sbjct: 577 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 636
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L+SL +N I + AF L + + L
Sbjct: 637 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 668
Score = 65.7 bits (153), Expect = 3e-10
Identities = 39/152 (25%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +V C L +P+ L ++T++ L ++ + AF+ R+LRR+ L
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQ 344
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ I P AF+GL L L + + + F L + ++L N+I I AF
Sbjct: 345 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 404
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
++L+SL +N I+ + F+ L + + L
Sbjct: 405 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHL 436
Score = 64.9 bits (151), Expect = 6e-10
Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 1/157 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R RL L+ N+TRI F GL +LR L + + V+ AF ++ + + L N+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL 260
+ + F ++ + L N I+ I AF G D+ ++L I IE AF L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
G+ VL L ++ ++ +F+ + ++ L + L
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 60.9 bits (141), Expect = 9e-09
Identities = 44/163 (26%), Positives = 79/163 (48%), Gaps = 2/163 (1%)
Query: 190 QNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
Q+ + L +N I+ +E+ F + I+L NN + I AF G V ++ L +
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
+ +I F GL+G+ L L + + D+F GL V LSL ++ + + G+FD
Sbjct: 600 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 659
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
LQ + TL + N + +L+ + + +TGN ++P+
Sbjct: 660 LQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPD 702
Score = 54.8 bits (126), Expect = 6e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I + AF + ++ ++ L
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + + L+L+ + ++ F G + L L ++ + I+ G+F L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R F+L NH+
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 54.4 bits (125), Expect = 8e-07
Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI + F+GL + ++L I +E AF ++ + L L L L
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F + RL L E+ + I +F G + L++ N+I IEE + + V
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 338 FKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ P + + ++ + NHL C+C + L C P
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGP 245
Query: 395 LKVRGRSLASATSGSAGCRGE 415
+RG ++A C G+
Sbjct: 246 ASLRGLNVAEVQKSEFSCSGQ 266
Score = 54.0 bits (124), Expect = 1e-06
Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+ +T I L N I I AF+ + I L NN I I AF GL + + L
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368
Query: 250 RTIEPQ-AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
T P+ F GL + +L L + + PD F L + LSL ++ + + G+F L
Sbjct: 369 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 428
Query: 309 QHVDTLEICNN 319
+ + TL + N
Sbjct: 429 RAIQTLHLAQN 439
Score = 49.2 bits (112), Expect = 3e-05
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 1/126 (0%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
I L N IK I AFS + +I+L + I I P AF GL + L L + L
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F GL + L L + + I+ +F LQ++ L + +NKI + + + +++
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQT 433
Query: 338 FKLTGN 343
L N
Sbjct: 434 LHLAQN 439
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Query: 109 LRGVPSG-LSP--SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL 165
++ +P G SP + ++ LS + + DAF LR L L L +T + F GL
Sbjct: 321 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 380
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L+ L + + + AF LQN++ + L N+I + F I + L NP
Sbjct: 381 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNP 440
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/104 (26%), Positives = 51/104 (49%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+++LS + + AF + L L A L IR FRGL LR L +++ ++ +
Sbjct: 569 KINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCI 628
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ +F L+N+ + L N+I + AF ++ ++L NP
Sbjct: 629 HNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672
Score = 45.2 bits (102), Expect = 5e-04
Identities = 30/125 (24%), Positives = 55/125 (44%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF +++L RL L+ L + F+ L L + + +
Sbjct: 90 LQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP 149
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF ++ ++ L N+I+ IE AF + +++L NN I I V +F+ + +
Sbjct: 150 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 209
Query: 243 IELPS 247
L S
Sbjct: 210 FRLHS 214
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/131 (21%), Positives = 63/131 (48%), Gaps = 2/131 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
CL + V C++ LR +P G+ +VT+L L ++ + + L+ + L ++
Sbjct: 740 CLD-TVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKIS 797
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ +F + +L L + + L + AF L+++ + L N I+ ++ FA
Sbjct: 798 SLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTS 857
Query: 216 INLISLRNNPI 226
++ +++ NP+
Sbjct: 858 LSHLAIGANPL 868
Score = 40.3 bits (90), Expect = 0.014
Identities = 27/82 (32%), Positives = 42/82 (51%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
SV++L L+ L +RS F L LR L L ++ I +F GL +R L + +
Sbjct: 590 SVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 649
Query: 179 ATVDSFAFAALQNITSIVLTHN 200
TV AF LQ+++++ L N
Sbjct: 650 TTVSPGAFDTLQSLSTLNLLAN 671
Score = 32.3 bits (70), Expect = 3.6
Identities = 23/108 (21%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
+G+P+ + ELY+ V + + + + L++N+I+ + + +F + + + L
Sbjct: 757 KGIPKNVTELYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLIL 815
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
N ++ I AF GL + + L + I T++ FA + + L +
Sbjct: 816 SYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAI 863
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 68.9 bits (161), Expect = 3e-11
Identities = 39/151 (25%), Positives = 76/151 (50%), Gaps = 1/151 (0%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C + +V C L +P+ L ++T++ L + ++V+ AF+ ++LRR+ L +
Sbjct: 281 CTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQI 340
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + P AF+GL L L + + + F L ++ ++L N+I + AF +
Sbjct: 341 SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLH 400
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+NL+SL +N ++ I FS L + + L
Sbjct: 401 NLNLLSLYDNKLQTIAKGTFSPLRAIQTMHL 431
Score = 62.5 bits (145), Expect = 3e-09
Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACNLTRIRPF 160
V C++ L +P + +L L+ + VL + F L QLR++ +T I
Sbjct: 513 VDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEG 572
Query: 161 AFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLIS 220
AF G + E+ + L V F L+++ +++L NRI + + +F G + + L+S
Sbjct: 573 AFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLS 632
Query: 221 LRNNPIKRILVHAFSGLNDVGQIEL 245
L +N I + AF L+ + + L
Sbjct: 633 LYDNQITTVAPGAFDTLHSLSTLNL 657
Score = 57.2 bits (132), Expect = 1e-07
Identities = 44/148 (29%), Positives = 63/148 (42%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S S V C+ ALR VP + + +L L+ ++ + FA LR LR L L ++ I
Sbjct: 35 SGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTI 94
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF+ L L L + L F + + L+ N+I I AF G I
Sbjct: 95 ERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIK 154
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L N I I AF L D+ + L
Sbjct: 155 NLQLDYNQISCIEDGAFRALRDLEVLTL 182
Score = 56.8 bits (131), Expect = 1e-07
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I I AF L ++ ++ L
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNH 114
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F G + L+L+ + ++ F G + + L L + + I+ G+F L
Sbjct: 115 LQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRAL 174
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I + S +R F+L N++
Sbjct: 175 RDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 52.4 bits (120), Expect = 3e-06
Identities = 33/125 (26%), Positives = 58/125 (46%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF L++L RL L+ +L F G +L L + + +
Sbjct: 84 LQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIP 143
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF +I ++ L +N+I+ IE AF + +++L NN I R+ V +F+ + +
Sbjct: 144 RKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRT 203
Query: 243 IELPS 247
L S
Sbjct: 204 FRLHS 208
Score = 51.2 bits (117), Expect = 7e-06
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 5/187 (2%)
Query: 190 QNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
Q + L +N +E+ F + I+ NN I I AF G + V +I L S
Sbjct: 529 QYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSN 588
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
+ ++ + F GLE + L L + + D+F GL V LSL ++ + + G+FD
Sbjct: 589 RLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDT 648
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV-VLEVENIIIRGNHL 366
L + TL + N + L+ + + +TGN + P + + ++++ I+
Sbjct: 649 LHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQ--DF 706
Query: 367 PCECGRD 373
C+ G D
Sbjct: 707 TCDDGND 713
Score = 49.2 bits (112), Expect = 3e-05
Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
I I L N IK I AFS + +I+L + I + P AF GL + L L +
Sbjct: 306 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 365
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
L F GL + L L + + ++V +F L +++ L + +NK+ I + + +
Sbjct: 366 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 425
Query: 335 VRVFKLTGN 343
++ L N
Sbjct: 426 IQTMHLAQN 434
Score = 46.8 bits (106), Expect = 2e-04
Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 1/108 (0%)
Query: 186 FAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
F L + I ++N+I IE AF G + +N I L +N ++ + F GL + + L
Sbjct: 550 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLML 609
Query: 246 PSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
S I + +F GL + +L L + ++ P F L + L+L
Sbjct: 610 RSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNL 657
Score = 44.4 bits (100), Expect = 8e-04
Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 2/115 (1%)
Query: 113 PSGLSP--SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
P SP + ++ LS + L DAF LR L L L +T + F GL L+
Sbjct: 321 PGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQL 380
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L + + + AF L N+ + L N++ I F+ I + L NP
Sbjct: 381 LLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNP 435
Score = 39.5 bits (88), Expect = 0.024
Identities = 23/104 (22%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R + L LD T + P L + + + ++T+ + +F+ + + +++L++NR
Sbjct: 750 RDVTELYLDGNQFTLV-PKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 808
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ I F G + L+SL N I + AF+ L+ + + +
Sbjct: 809 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAI 852
Score = 39.1 bits (87), Expect = 0.032
Identities = 33/169 (19%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I+ I P AF+ + + ++L+ + L PD F GL + L L + + + F+GL
Sbjct: 316 IKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGL 375
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM---LESPEAVVLEVENIIIRGNH 365
+ L + NKI+ + + +++ + L N + + + + ++ + + N
Sbjct: 376 FSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNP 435
Query: 366 LPCECGRDPFTNPLALSQDFAEENYCISPLKVRGRSLASATSGSAGCRG 414
C+C + L + C SP ++ + + S C G
Sbjct: 436 FICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSG 484
Score = 38.7 bits (86), Expect = 0.042
Identities = 22/108 (20%), Positives = 50/108 (46%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + +++ S + + AF + + L + L ++ F+GL L+ L ++
Sbjct: 554 PQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNR 613
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ V + +F L ++ + L N+I + AF + ++ ++L NP
Sbjct: 614 ITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANP 661
Score = 38.7 bits (86), Expect = 0.042
Identities = 22/73 (30%), Positives = 39/73 (53%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I T+ Q+F+ + + L L++ L + P TF GL + LSL +D+ ++ G+F+ L
Sbjct: 785 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL 844
Query: 309 QHVDTLEICNNKI 321
+ L I N +
Sbjct: 845 SALSHLAIGANPL 857
Score = 37.1 bits (82), Expect = 0.13
Identities = 26/131 (19%), Positives = 62/131 (47%), Gaps = 2/131 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
CL + V C++ L+ +P G+ VT+L L ++ + ++ + L + L ++
Sbjct: 729 CLD-TVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRIS 786
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ +F + +L L + + L + F L+++ + L N I+ + AF +
Sbjct: 787 TLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 846
Query: 216 INLISLRNNPI 226
++ +++ NP+
Sbjct: 847 LSHLAIGANPL 857
Score = 35.5 bits (78), Expect = 0.39
Identities = 20/66 (30%), Positives = 32/66 (48%)
Query: 289 RLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLES 348
RL L +++ I F GL+H+ L++ NKI IE + + +L NH+
Sbjct: 59 RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLF 118
Query: 349 PEAVVL 354
PE + L
Sbjct: 119 PELLFL 124
Score = 35.5 bits (78), Expect = 0.39
Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
+G+PR + ELY+ V + +++T I L++NRI+ + + +F+ + + L
Sbjct: 746 KGIPRDVTELYLDGNQFTLVPK-ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLIL 804
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ-AFAGLEGIGVLEL 268
N ++ I F GL + + L ++ P+ AF L + L +
Sbjct: 805 SYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAI 852
Score = 31.9 bits (69), Expect = 4.8
Identities = 19/100 (19%), Positives = 50/100 (50%), Gaps = 9/100 (9%)
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
++P+ LP+T + + L ++ + +I G+F + + +++ NN+I + +
Sbjct: 297 EIPTNLPET------ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQG 350
Query: 332 NNSVRVFKLTGNHMLESPEAV---VLEVENIIIRGNHLPC 368
S+ L GN + E P+++ + ++ +++ N + C
Sbjct: 351 LRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINC 390
Score = 31.5 bits (68), Expect = 6.4
Identities = 16/50 (32%), Positives = 25/50 (50%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+ L L + + AF LR L L L+ N+TR+ +F +P+LR
Sbjct: 153 IKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLR 202
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 68.9 bits (161), Expect = 3e-11
Identities = 39/151 (25%), Positives = 76/151 (50%), Gaps = 1/151 (0%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C + +V C L +P+ L ++T++ L + ++V+ AF+ ++LRR+ L +
Sbjct: 277 CTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQI 336
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + P AF+GL L L + + + F L ++ ++L N+I + AF +
Sbjct: 337 SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLH 396
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+NL+SL +N ++ I FS L + + L
Sbjct: 397 NLNLLSLYDNKLQTIAKGTFSPLRAIQTMHL 427
Score = 59.3 bits (137), Expect = 3e-08
Identities = 37/145 (25%), Positives = 67/145 (46%), Gaps = 1/145 (0%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACNLTRIRPF 160
V C++ L +P + +L L+ + VL + F L QLR++ +T I
Sbjct: 509 VDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEG 568
Query: 161 AFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLIS 220
AF G + E+ + L V F L+ +++L NRI + + +F G + + ++S
Sbjct: 569 AFEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLMLRSNRITCVGNDSFIGLSSVRMLS 628
Query: 221 LRNNPIKRILVHAFSGLNDVGQIEL 245
L +N I + AF L+ + + L
Sbjct: 629 LYDNQITTVAPGAFDTLHSLSTLNL 653
Score = 57.2 bits (132), Expect = 1e-07
Identities = 44/148 (29%), Positives = 63/148 (42%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S S V C+ ALR VP + + +L L+ ++ + FA LR LR L L ++ I
Sbjct: 35 SGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTI 94
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF+ L L L + L F + + L+ N+I I AF G I
Sbjct: 95 ERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIK 154
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L N I I AF L D+ + L
Sbjct: 155 NLQLDYNQISCIEDGAFRALRDLEVLTL 182
Score = 56.8 bits (131), Expect = 1e-07
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I I AF L ++ ++ L
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNH 114
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F G + L+L+ + ++ F G + + L L + + I+ G+F L
Sbjct: 115 LQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRAL 174
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I + S +R F+L N++
Sbjct: 175 RDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 52.4 bits (120), Expect = 3e-06
Identities = 33/125 (26%), Positives = 58/125 (46%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF L++L RL L+ +L F G +L L + + +
Sbjct: 84 LQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIP 143
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF +I ++ L +N+I+ IE AF + +++L NN I R+ V +F+ + +
Sbjct: 144 RKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRT 203
Query: 243 IELPS 247
L S
Sbjct: 204 FRLHS 208
Score = 49.2 bits (112), Expect = 3e-05
Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
I I L N IK I AFS + +I+L + I + P AF GL + L L +
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
L F GL + L L + + ++V +F L +++ L + +NK+ I + + +
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 335 VRVFKLTGN 343
++ L N
Sbjct: 422 IQTMHLAQN 430
Score = 45.6 bits (103), Expect = 4e-04
Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 1/108 (0%)
Query: 186 FAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
F L + I ++N+I IE AF G + +N I L +N ++ + F GL + L
Sbjct: 546 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLML 605
Query: 246 PSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
S I + +F GL + +L L + ++ P F L + L+L
Sbjct: 606 RSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLSTLNL 653
Score = 44.4 bits (100), Expect = 8e-04
Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 2/115 (1%)
Query: 113 PSGLSP--SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
P SP + ++ LS + L DAF LR L L L +T + F GL L+
Sbjct: 317 PGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQL 376
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L + + + AF L N+ + L N++ I F+ I + L NP
Sbjct: 377 LLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNP 431
Score = 39.5 bits (88), Expect = 0.024
Identities = 23/104 (22%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R + L LD T + P L + + + ++T+ + +F+ + + +++L++NR
Sbjct: 746 RDVTELYLDGNQFTLV-PKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 804
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ I F G + L+SL N I + AF+ L+ + + +
Sbjct: 805 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAI 848
Score = 39.1 bits (87), Expect = 0.032
Identities = 33/169 (19%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I+ I P AF+ + + ++L+ + L PD F GL + L L + + + F+GL
Sbjct: 312 IKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGL 371
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM---LESPEAVVLEVENIIIRGNH 365
+ L + NKI+ + + +++ + L N + + + + ++ + + N
Sbjct: 372 FSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNP 431
Query: 366 LPCECGRDPFTNPLALSQDFAEENYCISPLKVRGRSLASATSGSAGCRG 414
C+C + L + C SP ++ + + S C G
Sbjct: 432 FICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSG 480
Score = 38.7 bits (86), Expect = 0.042
Identities = 22/73 (30%), Positives = 39/73 (53%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I T+ Q+F+ + + L L++ L + P TF GL + LSL +D+ ++ G+F+ L
Sbjct: 781 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL 840
Query: 309 QHVDTLEICNNKI 321
+ L I N +
Sbjct: 841 SALSHLAIGANPL 853
Score = 37.5 bits (83), Expect = 0.097
Identities = 21/108 (19%), Positives = 50/108 (46%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + +++ S + + AF + + L + L ++ F+GL + + L ++
Sbjct: 550 PQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLMLRSNR 609
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ V + +F L ++ + L N+I + AF + ++ ++L NP
Sbjct: 610 ITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLSTLNLLANP 657
Score = 37.1 bits (82), Expect = 0.13
Identities = 26/131 (19%), Positives = 62/131 (47%), Gaps = 2/131 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
CL + V C++ L+ +P G+ VT+L L ++ + ++ + L + L ++
Sbjct: 725 CLD-TVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRIS 782
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ +F + +L L + + L + F L+++ + L N I+ + AF +
Sbjct: 783 TLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 842
Query: 216 INLISLRNNPI 226
++ +++ NP+
Sbjct: 843 LSHLAIGANPL 853
Score = 35.5 bits (78), Expect = 0.39
Identities = 20/66 (30%), Positives = 32/66 (48%)
Query: 289 RLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLES 348
RL L +++ I F GL+H+ L++ NKI IE + + +L NH+
Sbjct: 59 RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLF 118
Query: 349 PEAVVL 354
PE + L
Sbjct: 119 PELLFL 124
Score = 35.5 bits (78), Expect = 0.39
Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
+G+PR + ELY+ V + +++T I L++NRI+ + + +F+ + + L
Sbjct: 742 KGIPRDVTELYLDGNQFTLVPK-ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLIL 800
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ-AFAGLEGIGVLEL 268
N ++ I F GL + + L ++ P+ AF L + L +
Sbjct: 801 SYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAI 848
Score = 35.1 bits (77), Expect = 0.52
Identities = 26/95 (27%), Positives = 41/95 (43%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I IE AF G G+ + L L ++ F GL + L LR + + + SF GL
Sbjct: 562 ITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLMLRSNRITCVGNDSFIGL 621
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
V L + +N+I + + +S+ L N
Sbjct: 622 SSVRMLSLYDNQITTVAPGAFDTLHSLSTLNLLAN 656
Score = 32.7 bits (71), Expect = 2.8
Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 290 LSLRESDLGIIKV-GSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLES 348
L L ++ +++ G F L + + NNKI IEE + + V LT N +
Sbjct: 530 LRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 589
Query: 349 PEAVVLEVE---NIIIRGNHLPCECGRDPF 375
+ +E N+++R N + C G D F
Sbjct: 590 QHKMFKGLEKPQNLMLRSNRITC-VGNDSF 618
Score = 31.9 bits (69), Expect = 4.8
Identities = 19/100 (19%), Positives = 50/100 (50%), Gaps = 9/100 (9%)
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
++P+ LP+T + + L ++ + +I G+F + + +++ NN+I + +
Sbjct: 293 EIPTNLPET------ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQG 346
Query: 332 NNSVRVFKLTGNHMLESPEAV---VLEVENIIIRGNHLPC 368
S+ L GN + E P+++ + ++ +++ N + C
Sbjct: 347 LRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINC 386
Score = 31.5 bits (68), Expect = 6.4
Identities = 16/50 (32%), Positives = 25/50 (50%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+ L L + + AF LR L L L+ N+TR+ +F +P+LR
Sbjct: 153 IKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLR 202
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 68.9 bits (161), Expect = 3e-11
Identities = 39/151 (25%), Positives = 76/151 (50%), Gaps = 1/151 (0%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C + +V C L +P+ L ++T++ L + ++V+ AF+ ++LRR+ L +
Sbjct: 277 CTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQI 336
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
+ + P AF+GL L L + + + F L ++ ++L N+I + AF +
Sbjct: 337 SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLH 396
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+NL+SL +N ++ I FS L + + L
Sbjct: 397 NLNLLSLYDNKLQTIAKGTFSPLRAIQTMHL 427
Score = 62.5 bits (145), Expect = 3e-09
Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 1/145 (0%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACNLTRIRPF 160
V C++ L +P + +L L+ + VL + F L QLR++ +T I
Sbjct: 517 VDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEG 576
Query: 161 AFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLIS 220
AF G + E+ + L V F L+++ +++L NRI + + +F G + + L+S
Sbjct: 577 AFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLS 636
Query: 221 LRNNPIKRILVHAFSGLNDVGQIEL 245
L +N I + AF L+ + + L
Sbjct: 637 LYDNQITTVAPGAFDTLHSLSTLNL 661
Score = 57.2 bits (132), Expect = 1e-07
Identities = 44/148 (29%), Positives = 63/148 (42%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S S V C+ ALR VP + + +L L+ ++ + FA LR LR L L ++ I
Sbjct: 35 SGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTI 94
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF+ L L L + L F + + L+ N+I I AF G I
Sbjct: 95 ERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIK 154
Query: 218 LISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L N I I AF L D+ + L
Sbjct: 155 NLQLDYNQISCIEDGAFRALRDLEVLTL 182
Score = 56.8 bits (131), Expect = 1e-07
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I I AF L ++ ++ L
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNH 114
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F G + L+L+ + ++ F G + + L L + + I+ G+F L
Sbjct: 115 LQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRAL 174
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I + S +R F+L N++
Sbjct: 175 RDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 52.4 bits (120), Expect = 3e-06
Identities = 33/125 (26%), Positives = 58/125 (46%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF L++L RL L+ +L F G +L L + + +
Sbjct: 84 LQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIP 143
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF +I ++ L +N+I+ IE AF + +++L NN I R+ V +F+ + +
Sbjct: 144 RKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRT 203
Query: 243 IELPS 247
L S
Sbjct: 204 FRLHS 208
Score = 51.2 bits (117), Expect = 7e-06
Identities = 47/187 (25%), Positives = 84/187 (44%), Gaps = 5/187 (2%)
Query: 190 QNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
Q + L +N +E+ F + I+ NN I I AF G + V +I L S
Sbjct: 533 QYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSN 592
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
+ ++ + F GLE + L L + + D+F GL V LSL ++ + + G+FD
Sbjct: 593 RLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDT 652
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV-VLEVENIIIRGNHL 366
L + TL + N + L+ + + +TGN + P + + ++++ I+
Sbjct: 653 LHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQ--DF 710
Query: 367 PCECGRD 373
C+ G D
Sbjct: 711 TCDDGND 717
Score = 49.2 bits (112), Expect = 3e-05
Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
I I L N IK I AFS + +I+L + I + P AF GL + L L +
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKIT 361
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
L F GL + L L + + ++V +F L +++ L + +NK+ I + + +
Sbjct: 362 ELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRA 421
Query: 335 VRVFKLTGN 343
++ L N
Sbjct: 422 IQTMHLAQN 430
Score = 46.8 bits (106), Expect = 2e-04
Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 1/108 (0%)
Query: 186 FAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
F L + I ++N+I IE AF G + +N I L +N ++ + F GL + + L
Sbjct: 554 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLML 613
Query: 246 PSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSL 292
S I + +F GL + +L L + ++ P F L + L+L
Sbjct: 614 RSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNL 661
Score = 44.4 bits (100), Expect = 8e-04
Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 2/115 (1%)
Query: 113 PSGLSP--SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRE 170
P SP + ++ LS + L DAF LR L L L +T + F GL L+
Sbjct: 317 PGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQL 376
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L + + + AF L N+ + L N++ I F+ I + L NP
Sbjct: 377 LLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNP 431
Score = 39.5 bits (88), Expect = 0.024
Identities = 23/104 (22%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R + L LD T + P L + + + ++T+ + +F+ + + +++L++NR
Sbjct: 754 RDVTELYLDGNQFTLV-PKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 812
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ I F G + L+SL N I + AF+ L+ + + +
Sbjct: 813 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAI 856
Score = 38.7 bits (86), Expect = 0.042
Identities = 22/108 (20%), Positives = 50/108 (46%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + +++ S + + AF + + L + L ++ F+GL L+ L ++
Sbjct: 558 PQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNR 617
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ V + +F L ++ + L N+I + AF + ++ ++L NP
Sbjct: 618 ITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANP 665
Score = 38.7 bits (86), Expect = 0.042
Identities = 22/73 (30%), Positives = 39/73 (53%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I T+ Q+F+ + + L L++ L + P TF GL + LSL +D+ ++ G+F+ L
Sbjct: 789 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL 848
Query: 309 QHVDTLEICNNKI 321
+ L I N +
Sbjct: 849 SALSHLAIGANPL 861
Score = 37.1 bits (82), Expect = 0.13
Identities = 32/167 (19%), Positives = 69/167 (41%), Gaps = 3/167 (1%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I+ I P AF+ + + ++L+ + L PD F GL + L L + + + F+GL
Sbjct: 312 IKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGL 371
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM---LESPEAVVLEVENIIIRGNH 365
+ L + NKI+ + + +++ + L N + + + + ++ + + N
Sbjct: 372 FSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNP 431
Query: 366 LPCECGRDPFTNPLALSQDFAEENYCISPLKVRGRSLASATSGSAGC 412
C+C + L + C SP ++ + + S C
Sbjct: 432 FICDCHLKWLADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRC 478
Score = 37.1 bits (82), Expect = 0.13
Identities = 26/131 (19%), Positives = 62/131 (47%), Gaps = 2/131 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
CL + V C++ L+ +P G+ VT+L L ++ + ++ + L + L ++
Sbjct: 733 CLD-TVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKE-LSNYKHLTLIDLSNNRIS 790
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ +F + +L L + + L + F L+++ + L N I+ + AF +
Sbjct: 791 TLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 850
Query: 216 INLISLRNNPI 226
++ +++ NP+
Sbjct: 851 LSHLAIGANPL 861
Score = 35.5 bits (78), Expect = 0.39
Identities = 20/66 (30%), Positives = 32/66 (48%)
Query: 289 RLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLES 348
RL L +++ I F GL+H+ L++ NKI IE + + +L NH+
Sbjct: 59 RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLF 118
Query: 349 PEAVVL 354
PE + L
Sbjct: 119 PELLFL 124
Score = 35.5 bits (78), Expect = 0.39
Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
+G+PR + ELY+ V + +++T I L++NRI+ + + +F+ + + L
Sbjct: 750 KGIPRDVTELYLDGNQFTLVPK-ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLIL 808
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ-AFAGLEGIGVLEL 268
N ++ I F GL + + L ++ P+ AF L + L +
Sbjct: 809 SYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAI 856
Score = 31.9 bits (69), Expect = 4.8
Identities = 19/100 (19%), Positives = 50/100 (50%), Gaps = 9/100 (9%)
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
++P+ LP+T + + L ++ + +I G+F + + +++ NN+I + +
Sbjct: 293 EIPTNLPET------ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQG 346
Query: 332 NNSVRVFKLTGNHMLESPEAV---VLEVENIIIRGNHLPC 368
S+ L GN + E P+++ + ++ +++ N + C
Sbjct: 347 LRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINC 386
Score = 31.5 bits (68), Expect = 6.4
Identities = 16/50 (32%), Positives = 25/50 (50%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+ L L + + AF LR L L L+ N+TR+ +F +P+LR
Sbjct: 153 IKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLR 202
>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
Length = 1534
Score = 68.9 bits (161), Expect = 3e-11
Identities = 41/152 (26%), Positives = 76/152 (50%), Gaps = 2/152 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C ++ VV C+S L +P + S +L L+ ++ +L + F L L+++ L
Sbjct: 517 CRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNK 576
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
++ I AF G + EL++ L ++ S F L + +++L +NRI+ I + +F G
Sbjct: 577 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 636
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L+SL +N I + AF L + + L
Sbjct: 637 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 668
Score = 65.7 bits (153), Expect = 3e-10
Identities = 39/152 (25%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +V C L +P+ L ++T++ L ++ + AF+ R+LRR+ L
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQ 344
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ I P AF+GL L L + + + F L + ++L N+I I AF
Sbjct: 345 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 404
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
++L+SL +N I+ + F+ L + + L
Sbjct: 405 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHL 436
Score = 64.1 bits (149), Expect = 1e-09
Identities = 42/157 (26%), Positives = 72/157 (45%), Gaps = 1/157 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R RL L+ N+TRI F GL +LR L + + V+ AF ++ + + L N+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL 260
+ + F ++ + L N I+ I AF G D+ + L I IE AF L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRAL 180
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
G+ VL L ++ ++ +F+ + ++ L + L
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 60.9 bits (141), Expect = 9e-09
Identities = 44/163 (26%), Positives = 79/163 (48%), Gaps = 2/163 (1%)
Query: 190 QNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
Q+ + L +N I+ +E+ F + I+L NN + I AF G V ++ L +
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
+ +I F GL+G+ L L + + D+F GL V LSL ++ + + G+FD
Sbjct: 600 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 659
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
LQ + TL + N + +L+ + + +TGN ++P+
Sbjct: 660 LQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPD 702
Score = 54.4 bits (125), Expect = 8e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I + AF + ++ ++ L
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + + L+L+ + ++ F G + L L ++ + I+ G+F L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRAL 180
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R F+L NH+
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 54.0 bits (124), Expect = 1e-06
Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+ +T I L N I I AF+ + I L NN I I AF GL + + L
Sbjct: 309 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 368
Query: 250 RTIEPQ-AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
T P+ F GL + +L L + + PD F L + LSL ++ + + G+F L
Sbjct: 369 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 428
Query: 309 QHVDTLEICNN 319
+ + TL + N
Sbjct: 429 RAIQTLHLAQN 439
Score = 53.6 bits (123), Expect = 1e-06
Identities = 48/201 (23%), Positives = 80/201 (39%), Gaps = 4/201 (1%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI + F+GL + ++L I +E AF ++ + L L L L
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F + RL L E+ + I +F G + L + N+I IEE + + V
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEV 185
Query: 338 FKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ P + + ++ + NHL C+C + L C P
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGP 245
Query: 395 LKVRGRSLASATSGSAGCRGE 415
+RG ++A C G+
Sbjct: 246 ASLRGLNVAEVQKSEFSCSGQ 266
Score = 49.2 bits (112), Expect = 3e-05
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 1/126 (0%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
I L N IK I AFS + +I+L + I I P AF GL + L L + L
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F GL + L L + + I+ +F LQ++ L + +NKI + + + +++
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQT 433
Query: 338 FKLTGN 343
L N
Sbjct: 434 LHLAQN 439
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Query: 109 LRGVPSG-LSP--SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL 165
++ +P G SP + ++ LS + + DAF LR L L L +T + F GL
Sbjct: 321 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 380
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L+ L + + + AF LQN++ + L N+I + F I + L NP
Sbjct: 381 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNP 440
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/104 (26%), Positives = 51/104 (49%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+++LS + + AF + L L A L IR FRGL LR L +++ ++ +
Sbjct: 569 KINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCI 628
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ +F L+N+ + L N+I + AF ++ ++L NP
Sbjct: 629 HNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 672
Score = 44.8 bits (101), Expect = 6e-04
Identities = 30/125 (24%), Positives = 55/125 (44%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF +++L RL L+ L + F+ L L + + +
Sbjct: 90 LQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP 149
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF ++ ++ L N+I+ IE AF + +++L NN I I V +F+ + +
Sbjct: 150 RKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 209
Query: 243 IELPS 247
L S
Sbjct: 210 FRLHS 214
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/131 (21%), Positives = 63/131 (48%), Gaps = 2/131 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
CL + V C++ LR +P G+ +VT+L L ++ + + L+ + L ++
Sbjct: 740 CLD-TVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKIS 797
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ +F + +L L + + L + AF L+++ + L N I+ ++ FA
Sbjct: 798 SLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTS 857
Query: 216 INLISLRNNPI 226
++ +++ NP+
Sbjct: 858 LSHLAIGANPL 868
Score = 40.3 bits (90), Expect = 0.014
Identities = 27/82 (32%), Positives = 42/82 (51%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
SV++L L+ L +RS F L LR L L ++ I +F GL +R L + +
Sbjct: 590 SVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 649
Query: 179 ATVDSFAFAALQNITSIVLTHN 200
TV AF LQ+++++ L N
Sbjct: 650 TTVSPGAFDTLQSLSTLNLLAN 671
Score = 32.3 bits (70), Expect = 3.6
Identities = 23/108 (21%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
+G+P+ + ELY+ V + + + + L++N+I+ + + +F + + + L
Sbjct: 757 KGIPKNVTELYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLIL 815
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
N ++ I AF GL + + L + I T++ FA + + L +
Sbjct: 816 SYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAI 863
>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
Length = 1618
Score = 68.9 bits (161), Expect = 3e-11
Identities = 41/152 (26%), Positives = 76/152 (50%), Gaps = 2/152 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C ++ VV C+S L +P + S +L L+ ++ +L + F L L+++ L
Sbjct: 601 CRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNK 660
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
++ I AF G + EL++ L ++ S F L + +++L +NRI+ I + +F G
Sbjct: 661 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 720
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ L+SL +N I + AF L + + L
Sbjct: 721 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNL 752
Score = 65.7 bits (153), Expect = 3e-10
Identities = 39/152 (25%), Positives = 72/152 (47%), Gaps = 1/152 (0%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +V C L +P+ L ++T++ L ++ + AF+ R+LRR+ L
Sbjct: 369 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQ 428
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ I P AF+GL L L + + + F L + ++L N+I I AF
Sbjct: 429 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 488
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
++L+SL +N I+ + F+ L + + L
Sbjct: 489 QNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHL 520
Score = 64.9 bits (151), Expect = 6e-10
Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 1/157 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R RL L+ N+TRI F GL +LR L + + V+ AF ++ + + L N+
Sbjct: 145 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQ 204
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL 260
+ + F ++ + L N I+ I AF G D+ ++L I IE AF L
Sbjct: 205 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 264
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
G+ VL L ++ ++ +F+ + ++ L + L
Sbjct: 265 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 60.9 bits (141), Expect = 9e-09
Identities = 44/163 (26%), Positives = 79/163 (48%), Gaps = 2/163 (1%)
Query: 190 QNITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
Q+ + L +N I+ +E+ F + I+L NN + I AF G V ++ L +
Sbjct: 624 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 683
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
+ +I F GL+G+ L L + + D+F GL V LSL ++ + + G+FD
Sbjct: 684 QLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDT 743
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPE 350
LQ + TL + N + +L+ + + +TGN ++P+
Sbjct: 744 LQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPD 786
Score = 54.4 bits (125), Expect = 8e-07
Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI + F+GL + ++L I +E AF ++ + L L L L
Sbjct: 150 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLP 209
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F + RL L E+ + I +F G + L++ N+I IEE + + V
Sbjct: 210 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 269
Query: 338 FKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ P + + ++ + NHL C+C + L C P
Sbjct: 270 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGP 329
Query: 395 LKVRGRSLASATSGSAGCRGE 415
+RG ++A C G+
Sbjct: 330 ASLRGLNVAEVQKSEFSCSGQ 350
Score = 54.0 bits (124), Expect = 1e-06
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I + AF + ++ ++ L
Sbjct: 145 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQ 204
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + + L+L+ + ++ F G + L L ++ + I+ G+F L
Sbjct: 205 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 264
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R F+L NH+
Sbjct: 265 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 54.0 bits (124), Expect = 1e-06
Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+ +T I L N I I AF+ + I L NN I I AF GL + + L
Sbjct: 393 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 452
Query: 250 RTIEPQ-AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
T P+ F GL + +L L + + PD F L + LSL ++ + + G+F L
Sbjct: 453 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSL 512
Query: 309 QHVDTLEICNN 319
+ + TL + N
Sbjct: 513 RAIQTLHLAQN 523
Score = 49.2 bits (112), Expect = 3e-05
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 1/126 (0%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
I L N IK I AFS + +I+L + I I P AF GL + L L + L
Sbjct: 398 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 457
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F GL + L L + + I+ +F LQ++ L + +NKI + + + +++
Sbjct: 458 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQT 517
Query: 338 FKLTGN 343
L N
Sbjct: 518 LHLAQN 523
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Query: 109 LRGVPSG-LSP--SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGL 165
++ +P G SP + ++ LS + + DAF LR L L L +T + F GL
Sbjct: 405 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 464
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
L+ L + + + AF LQN++ + L N+I + F I + L NP
Sbjct: 465 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNP 524
Score = 47.2 bits (107), Expect = 1e-04
Identities = 28/104 (26%), Positives = 51/104 (49%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+++LS + + AF + L L A L IR FRGL LR L +++ ++ +
Sbjct: 653 KINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCI 712
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+ +F L+N+ + L N+I + AF ++ ++L NP
Sbjct: 713 HNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANP 756
Score = 46.8 bits (106), Expect = 2e-04
Identities = 31/125 (24%), Positives = 56/125 (44%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + V+ AF +++L RL L+ L + F+ L L + + +
Sbjct: 174 LQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP 233
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF ++ ++ L N+I+ IE AF + +++L NN I I V +F+ + +
Sbjct: 234 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 293
Query: 243 IELPS 247
L S
Sbjct: 294 FRLHS 298
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/131 (21%), Positives = 63/131 (48%), Gaps = 2/131 (1%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
CL + V C++ LR +P G+ +VT+L L ++ + + L+ + L ++
Sbjct: 824 CLD-TVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQ-LSTFKYLQLVDLSNNKIS 881
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ +F + +L L + + L + AF L+++ + L N I+ ++ FA
Sbjct: 882 SLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTS 941
Query: 216 INLISLRNNPI 226
++ +++ NP+
Sbjct: 942 LSHLAIGANPL 952
Score = 40.3 bits (90), Expect = 0.014
Identities = 27/82 (32%), Positives = 42/82 (51%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
SV++L L+ L +RS F L LR L L ++ I +F GL +R L + +
Sbjct: 674 SVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQI 733
Query: 179 ATVDSFAFAALQNITSIVLTHN 200
TV AF LQ+++++ L N
Sbjct: 734 TTVSPGAFDTLQSLSTLNLLAN 755
Score = 32.3 bits (70), Expect = 3.6
Identities = 23/108 (21%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Query: 163 RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
+G+P+ + ELY+ V + + + + L++N+I+ + + +F + + + L
Sbjct: 841 KGIPKNVTELYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLIL 899
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLEL 268
N ++ I AF GL + + L + I T++ FA + + L +
Sbjct: 900 SYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAI 947
>BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein.
Length = 384
Score = 68.1 bits (159), Expect = 6e-11
Identities = 59/243 (24%), Positives = 108/243 (44%), Gaps = 13/243 (5%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C S+VV C+ L VP+ + L L ++ ++ + F L L L L+ L
Sbjct: 83 CQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKL 142
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T+I P AF +LR LY+ H L+ + +++ + + N++ +I+ F G N
Sbjct: 143 TKIHPKAFLTTKKLRRLYLSHNQLSEI---PLNLPKSLAELRIHENKVKKIQKDTFKGMN 199
Query: 215 FINLISLRNNPIKR--ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMD 272
++++ + NP+ I AF G+ V I + T P+ + L L +
Sbjct: 200 ALHVLEMSANPLDNNGIEPGAFEGVT-VFHIRIAEAKLTSVPKGLP--PTLLELHLDYNK 256
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELS 328
+ ++ + F + RL L + + I+ GS + V + + NNK+ G+ EL
Sbjct: 257 ISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPELK 316
Query: 329 LVQ 331
+Q
Sbjct: 317 YLQ 319
Score = 56.0 bits (129), Expect = 3e-07
Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
Query: 107 AALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLP 166
A L VP GL P++ +L L + + + F ++L+RL L +T I + +P
Sbjct: 234 AKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIP 293
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT------NFINLIS 220
R+RE+++++ L + S L+ + I L N IA++ F T + + IS
Sbjct: 294 RVREIHLENNKLKKIPS-GLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAIS 352
Query: 221 LRNNPIK 227
L NNP+K
Sbjct: 353 LFNNPVK 359
>AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein.
Length = 379
Score = 68.1 bits (159), Expect = 6e-11
Identities = 59/243 (24%), Positives = 108/243 (44%), Gaps = 13/243 (5%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C S+VV C+ L VP+ + L L ++ ++ + F L L L L+ L
Sbjct: 78 CQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKL 137
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T+I P AF +LR LY+ H L+ + +++ + + N++ +I+ F G N
Sbjct: 138 TKIHPKAFLTTKKLRRLYLSHNQLSEI---PLNLPKSLAELRIHENKVKKIQKDTFKGMN 194
Query: 215 FINLISLRNNPIKR--ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMD 272
++++ + NP+ I AF G+ V I + T P+ + L L +
Sbjct: 195 ALHVLEMSANPLDNNGIEPGAFEGVT-VFHIRIAEAKLTSVPKGLP--PTLLELHLDYNK 251
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELS 328
+ ++ + F + RL L + + I+ GS + V + + NNK+ G+ EL
Sbjct: 252 ISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPELK 311
Query: 329 LVQ 331
+Q
Sbjct: 312 YLQ 314
Score = 56.0 bits (129), Expect = 3e-07
Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
Query: 107 AALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLP 166
A L VP GL P++ +L L + + + F ++L+RL L +T I + +P
Sbjct: 229 AKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIP 288
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT------NFINLIS 220
R+RE+++++ L + S L+ + I L N IA++ F T + + IS
Sbjct: 289 RVREIHLENNKLKKIPS-GLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAIS 347
Query: 221 LRNNPIK 227
L NNP+K
Sbjct: 348 LFNNPVK 354
>AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament
associated protein 1 protein.
Length = 381
Score = 68.1 bits (159), Expect = 6e-11
Identities = 59/243 (24%), Positives = 108/243 (44%), Gaps = 13/243 (5%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C S+VV C+ L VP+ + L L ++ ++ + F L L L L+ L
Sbjct: 80 CQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKL 139
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T+I P AF +LR LY+ H L+ + +++ + + N++ +I+ F G N
Sbjct: 140 TKIHPKAFLTTKKLRRLYLSHNQLSEI---PLNLPKSLAELRIHENKVKKIQKDTFKGMN 196
Query: 215 FINLISLRNNPIKR--ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMD 272
++++ + NP+ I AF G+ V I + T P+ + L L +
Sbjct: 197 ALHVLEMSANPLDNNGIEPGAFEGVT-VFHIRIAEAKLTSVPKGLP--PTLLELHLDYNK 253
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELS 328
+ ++ + F + RL L + + I+ GS + V + + NNK+ G+ EL
Sbjct: 254 ISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPELK 313
Query: 329 LVQ 331
+Q
Sbjct: 314 YLQ 316
Score = 56.0 bits (129), Expect = 3e-07
Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
Query: 107 AALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLP 166
A L VP GL P++ +L L + + + F ++L+RL L +T I + +P
Sbjct: 231 AKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIP 290
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT------NFINLIS 220
R+RE+++++ L + S L+ + I L N IA++ F T + + IS
Sbjct: 291 RVREIHLENNKLKKIPS-GLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAIS 349
Query: 221 LRNNPIK 227
L NNP+K
Sbjct: 350 LFNNPVK 356
>AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1)
protein.
Length = 380
Score = 68.1 bits (159), Expect = 6e-11
Identities = 59/243 (24%), Positives = 108/243 (44%), Gaps = 13/243 (5%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C S+VV C+ L VP+ + L L ++ ++ + F L L L L+ L
Sbjct: 79 CQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKL 138
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T+I P AF +LR LY+ H L+ + +++ + + N++ +I+ F G N
Sbjct: 139 TKIHPKAFLTTKKLRRLYLSHNQLSEI---PLNLPKSLAELRIHENKVKKIQKDTFKGMN 195
Query: 215 FINLISLRNNPIKR--ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMD 272
++++ + NP+ I AF G+ V I + T P+ + L L +
Sbjct: 196 ALHVLEMSANPLDNNGIEPGAFEGVT-VFHIRIAEAKLTSVPKGLP--PTLLELHLDYNK 252
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELS 328
+ ++ + F + RL L + + I+ GS + V + + NNK+ G+ EL
Sbjct: 253 ISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPELK 312
Query: 329 LVQ 331
+Q
Sbjct: 313 YLQ 315
Score = 56.0 bits (129), Expect = 3e-07
Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
Query: 107 AALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLP 166
A L VP GL P++ +L L + + + F ++L+RL L +T I + +P
Sbjct: 230 AKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIP 289
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT------NFINLIS 220
R+RE+++++ L + S L+ + I L N IA++ F T + + IS
Sbjct: 290 RVREIHLENNKLKKIPS-GLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAIS 348
Query: 221 LRNNPIK 227
L NNP+K
Sbjct: 349 LFNNPVK 355
>AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein.
Length = 379
Score = 68.1 bits (159), Expect = 6e-11
Identities = 59/243 (24%), Positives = 108/243 (44%), Gaps = 13/243 (5%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C S+VV C+ L VP+ + L L ++ ++ + F L L L L+ L
Sbjct: 78 CQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKL 137
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T+I P AF +LR LY+ H L+ + +++ + + N++ +I+ F G N
Sbjct: 138 TKIHPKAFLTTKKLRRLYLSHNQLSEI---PLNLPKSLAELRIHENKVKKIQKDTFKGMN 194
Query: 215 FINLISLRNNPIKR--ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMD 272
++++ + NP+ I AF G+ V I + T P+ + L L +
Sbjct: 195 ALHVLEMSANPLDNNGIEPGAFEGVT-VFHIRIAEAKLTSVPKGLP--PTLLELHLDYNK 251
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELS 328
+ ++ + F + RL L + + I+ GS + V + + NNK+ G+ EL
Sbjct: 252 ISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPELK 311
Query: 329 LVQ 331
+Q
Sbjct: 312 YLQ 314
Score = 56.0 bits (129), Expect = 3e-07
Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
Query: 107 AALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLP 166
A L VP GL P++ +L L + + + F ++L+RL L +T I + +P
Sbjct: 229 AKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIP 288
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT------NFINLIS 220
R+RE+++++ L + S L+ + I L N IA++ F T + + IS
Sbjct: 289 RVREIHLENNKLKKIPS-GLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAIS 347
Query: 221 LRNNPIK 227
L NNP+K
Sbjct: 348 LFNNPVK 354
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 66.9 bits (156), Expect = 1e-10
Identities = 47/139 (33%), Positives = 76/139 (54%), Gaps = 2/139 (1%)
Query: 185 AFAALQNITSIV-LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQI 243
A A+ TSI+ L NRI +I+ AF +N + L NN IKRI AF L ++ +
Sbjct: 73 AVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYL 132
Query: 244 EL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKV 302
L + I++I+ QAF GL + L L F + +L PD+F L ++ RL L + + +
Sbjct: 133 YLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVP 192
Query: 303 GSFDGLQHVDTLEICNNKI 321
G+F+ L+ + L + +N +
Sbjct: 193 GTFNHLESMKRLRLDSNTL 211
Score = 61.7 bits (143), Expect = 5e-09
Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Query: 96 CLS-QSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
CL ++ V C L VP+ ++P + L L +R ++ AF LR L L L+ +
Sbjct: 57 CLCFRTTVRCMHLLLEAVPA-VAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQI 115
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
RI AF L L+ LY+ + ++D AF L ++ + L N+I ++ +F
Sbjct: 116 KRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLP 175
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+ + L NN I ++ F+ L + ++ L S
Sbjct: 176 KLERLFLHNNRITHLVPGTFNHLESMKRLRLDS 208
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/108 (25%), Positives = 50/108 (46%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L L+ ++ + S AF L L+ L L + I AF+GL L +LY+ +
Sbjct: 104 NLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQI 163
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
T+D +F L + + L +NRI + F + + L +N +
Sbjct: 164 ETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTL 211
Score = 40.7 bits (91), Expect = 0.010
Identities = 33/128 (25%), Positives = 60/128 (46%), Gaps = 1/128 (0%)
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPS 275
+++ LR N I+ I AF L ++ + L + I+ I AF LE + L L ++ S
Sbjct: 82 SILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQS 141
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSV 335
+ F GL + +L L + + + SF L ++ L + NN+I + + S+
Sbjct: 142 IDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESM 201
Query: 336 RVFKLTGN 343
+ +L N
Sbjct: 202 KRLRLDSN 209
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 66.9 bits (156), Expect = 1e-10
Identities = 47/139 (33%), Positives = 76/139 (54%), Gaps = 2/139 (1%)
Query: 185 AFAALQNITSIV-LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQI 243
A A+ TSI+ L NRI +I+ AF +N + L NN IKRI AF L ++ +
Sbjct: 51 AVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYL 110
Query: 244 EL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKV 302
L + I++I+ QAF GL + L L F + +L PD+F L ++ RL L + + +
Sbjct: 111 YLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVP 170
Query: 303 GSFDGLQHVDTLEICNNKI 321
G+F+ L+ + L + +N +
Sbjct: 171 GTFNHLESMKRLRLDSNTL 189
Score = 61.7 bits (143), Expect = 5e-09
Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Query: 96 CLS-QSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
CL ++ V C L VP+ ++P + L L +R ++ AF LR L L L+ +
Sbjct: 35 CLCFRTTVRCMHLLLEAVPA-VAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQI 93
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
RI AF L L+ LY+ + ++D AF L ++ + L N+I ++ +F
Sbjct: 94 KRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLP 153
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+ + L NN I ++ F+ L + ++ L S
Sbjct: 154 KLERLFLHNNRITHLVPGTFNHLESMKRLRLDS 186
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/108 (25%), Positives = 50/108 (46%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L L+ ++ + S AF L L+ L L + I AF+GL L +LY+ +
Sbjct: 82 NLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQI 141
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
T+D +F L + + L +NRI + F + + L +N +
Sbjct: 142 ETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTL 189
Score = 40.7 bits (91), Expect = 0.010
Identities = 33/128 (25%), Positives = 60/128 (46%), Gaps = 1/128 (0%)
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPS 275
+++ LR N I+ I AF L ++ + L + I+ I AF LE + L L ++ S
Sbjct: 60 SILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQS 119
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSV 335
+ F GL + +L L + + + SF L ++ L + NN+I + + S+
Sbjct: 120 IDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESM 179
Query: 336 RVFKLTGN 343
+ +L N
Sbjct: 180 KRLRLDSN 187
>BC044233-1|AAH44233.1| 692|Homo sapiens leucine rich repeat
containing 33 protein.
Length = 692
Score = 66.9 bits (156), Expect = 1e-10
Identities = 65/247 (26%), Positives = 112/247 (45%), Gaps = 10/247 (4%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C +L VPS L P L+L L+ L + + L L+L +C+L RI AF+
Sbjct: 43 CRGQSLASVPSSLPPHARMLTLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQ 102
Query: 164 GLPRLRELYIQHTPLA---TVDSFAFAALQNITSIVLTHNRIAQ-IESYAFAGTNFINLI 219
LR L + L+ + A AL + + L+ N + + + + + + +
Sbjct: 103 EQGHLRSLVLGDNCLSENYEETAAALHALPGLRRLDLSGNALTEDMAALMLQNLSSLRSV 162
Query: 220 SLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLP 278
SL N I R+ F GL + +++L I IE AF GL + L LAF +LP ++
Sbjct: 163 SLAGNTIMRLDDSVFEGLERLRELDLQRNYIFEIEGGAFDGLAELRHLNLAFNNLPCIVD 222
Query: 279 DTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVF 338
GL R+ L++ + L + ++TL++ +N++ + L Q + +R
Sbjct: 223 ---FGLTRLRVLNVSYNVLEWFLATGGEAAFELETLDLSHNQL--LFFPLLPQYSKLRTL 277
Query: 339 KLTGNHM 345
L N+M
Sbjct: 278 LLRDNNM 284
Score = 38.7 bits (86), Expect = 0.042
Identities = 46/209 (22%), Positives = 82/209 (39%), Gaps = 11/209 (5%)
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
P R L + PL T+ + + + S+ L + +I AF + + L +N
Sbjct: 57 PHARMLTLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQEQGHLRSLVLGDNC 116
Query: 226 IKR------ILVHAFSGLNDVGQIELPSGIRTIEPQAFA--GLEGIGVLELAFMDLPSLL 277
+ +HA GL +++L T + A L + + LA + L
Sbjct: 117 LSENYEETAAALHALPGLR---RLDLSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLD 173
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F GL R+ L L+ + + I+ G+FDGL + L + N + I + L + + V
Sbjct: 174 DSVFEGLERLRELDLQRNYIFEIEGGAFDGLAELRHLNLAFNNLPCIVDFGLTRLRVLNV 233
Query: 338 FKLTGNHMLESPEAVVLEVENIIIRGNHL 366
L + E+E + + N L
Sbjct: 234 SYNVLEWFLATGGEAAFELETLDLSHNQL 262
>AY358322-1|AAQ88688.1| 692|Homo sapiens ELLP3030 protein.
Length = 692
Score = 66.9 bits (156), Expect = 1e-10
Identities = 65/247 (26%), Positives = 112/247 (45%), Gaps = 10/247 (4%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C +L VPS L P L+L L+ L + + L L+L +C+L RI AF+
Sbjct: 43 CRGQSLASVPSSLPPHARMLTLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQ 102
Query: 164 GLPRLRELYIQHTPLA---TVDSFAFAALQNITSIVLTHNRIAQ-IESYAFAGTNFINLI 219
LR L + L+ + A AL + + L+ N + + + + + + +
Sbjct: 103 EQGHLRSLVLGDNCLSENYEETAAALHALPGLRRLDLSGNALTEDMAALMLQNLSSLRSV 162
Query: 220 SLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLP 278
SL N I R+ F GL + +++L I IE AF GL + L LAF +LP ++
Sbjct: 163 SLAGNTIMRLDDSVFEGLERLRELDLQRNYIFEIEGGAFDGLAELRHLNLAFNNLPCIVD 222
Query: 279 DTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVF 338
GL R+ L++ + L + ++TL++ +N++ + L Q + +R
Sbjct: 223 ---FGLTRLRVLNVSYNVLEWFLATGGEAAFELETLDLSHNQL--LFFPLLPQYSKLRTL 277
Query: 339 KLTGNHM 345
L N+M
Sbjct: 278 LLRDNNM 284
Score = 38.7 bits (86), Expect = 0.042
Identities = 46/209 (22%), Positives = 82/209 (39%), Gaps = 11/209 (5%)
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
P R L + PL T+ + + + S+ L + +I AF + + L +N
Sbjct: 57 PHARMLTLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQEQGHLRSLVLGDNC 116
Query: 226 IKR------ILVHAFSGLNDVGQIELPSGIRTIEPQAFA--GLEGIGVLELAFMDLPSLL 277
+ +HA GL +++L T + A L + + LA + L
Sbjct: 117 LSENYEETAAALHALPGLR---RLDLSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLD 173
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F GL R+ L L+ + + I+ G+FDGL + L + N + I + L + + V
Sbjct: 174 DSVFEGLERLRELDLQRNYIFEIEGGAFDGLAELRHLNLAFNNLPCIVDFGLTRLRVLNV 233
Query: 338 FKLTGNHMLESPEAVVLEVENIIIRGNHL 366
L + E+E + + N L
Sbjct: 234 SYNVLEWFLATGGEAAFELETLDLSHNQL 262
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 66.9 bits (156), Expect = 1e-10
Identities = 47/139 (33%), Positives = 76/139 (54%), Gaps = 2/139 (1%)
Query: 185 AFAALQNITSIV-LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQI 243
A A+ TSI+ L NRI +I+ AF +N + L NN IKRI AF L ++ +
Sbjct: 73 AVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYL 132
Query: 244 EL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKV 302
L + I++I+ QAF GL + L L F + +L PD+F L ++ RL L + + +
Sbjct: 133 YLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVP 192
Query: 303 GSFDGLQHVDTLEICNNKI 321
G+F+ L+ + L + +N +
Sbjct: 193 GTFNHLESMKRLRLDSNTL 211
Score = 61.7 bits (143), Expect = 5e-09
Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Query: 96 CLS-QSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
CL ++ V C L VP+ ++P + L L +R ++ AF LR L L L+ +
Sbjct: 57 CLCFRTTVRCMHLLLEAVPA-VAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQI 115
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
RI AF L L+ LY+ + ++D AF L ++ + L N+I ++ +F
Sbjct: 116 KRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLP 175
Query: 215 FINLISLRNNPIKRILVHAFSGLNDVGQIELPS 247
+ + L NN I ++ F+ L + ++ L S
Sbjct: 176 KLERLFLHNNRITHLVPGTFNHLESMKRLRLDS 208
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/108 (25%), Positives = 50/108 (46%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ L L+ ++ + S AF L L+ L L + I AF+GL L +LY+ +
Sbjct: 104 NLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQI 163
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
T+D +F L + + L +NRI + F + + L +N +
Sbjct: 164 ETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNTL 211
Score = 40.7 bits (91), Expect = 0.010
Identities = 33/128 (25%), Positives = 60/128 (46%), Gaps = 1/128 (0%)
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPS 275
+++ LR N I+ I AF L ++ + L + I+ I AF LE + L L ++ S
Sbjct: 82 SILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQS 141
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSV 335
+ F GL + +L L + + + SF L ++ L + NN+I + + S+
Sbjct: 142 IDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESM 201
Query: 336 RVFKLTGN 343
+ +L N
Sbjct: 202 KRLRLDSN 209
>BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 65.7 bits (153), Expect = 3e-10
Identities = 63/230 (27%), Positives = 109/230 (47%), Gaps = 15/230 (6%)
Query: 105 NSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTR--IRPFAF 162
+S L VP+GL S+ L L + +R + ++ +R L L L + L I P AF
Sbjct: 344 SSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 403
Query: 163 RGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
+GL RL +++ + L V S + + ++++ HN+I I FA T F+ ++L
Sbjct: 404 QGLKRLHTVHLYNNALERVPS---GLPRRVRTLMILHNQITGIGREDFATTYFLEELNLS 460
Query: 223 NNPIKRILVH--AFSGLNDVGQIELPSG-IRTIEPQAFAGL-EGIGVLELAFMDLPSLLP 278
N I VH AF L + ++L + T+ P GL + VL++ +L +L
Sbjct: 461 YNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPP----GLPRNVHVLKVKRNELAALAR 516
Query: 279 DTFHGLIRVGRLSLRESDLGIIKVG--SFDGLQHVDTLEICNNKIDGIEE 326
G+ ++ L L + L +G ++ L H+ L+I N++ I E
Sbjct: 517 GALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE 566
Score = 43.6 bits (98), Expect = 0.001
Identities = 64/301 (21%), Positives = 128/301 (42%), Gaps = 22/301 (7%)
Query: 105 NSAALRGVPSGLSPSVTQLS-LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
N RG+P +T L+ L A+ ++ + F L + A LT+I F
Sbjct: 178 NRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLP-NALISVDFAANYLTKIYGLTFG 236
Query: 164 GLPRLRELYIQHTPLAT--VDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
P LR +Y+ + LA + F N+ ++L+ N + + + + + L
Sbjct: 237 QKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA---LYKLHL 293
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSGIRT---IEPQAFAGLEGIGVLELAFMDL---PS 275
+NN +++I AFS L+ + ++ L + T ++ + F L + L+L+ +L P+
Sbjct: 294 KNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPA 353
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI--DGIEELSLVQNN 333
LP + L+ + + ++R D ++ ++ ++ L + +N++ GI L+
Sbjct: 354 GLPRSL-VLLHLEKNAIRSVDANVL-----TPIRSLEYLLLHSNQLREQGIHPLAFQGLK 407
Query: 334 SVRVFKLTGNHMLESPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
+ L N + P + V ++I N + GR+ F L + N S
Sbjct: 408 RLHTVHLYNNALERVPSGLPRRVRTLMILHNQI-TGIGREDFATTYFLEELNLSYNRITS 466
Query: 394 P 394
P
Sbjct: 467 P 467
Score = 37.9 bits (84), Expect = 0.073
Identities = 69/317 (21%), Positives = 136/317 (42%), Gaps = 56/317 (17%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT------ 155
++ +S LR VP L P++ +L L L + AF+ L LR L L LT
Sbjct: 270 LILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDN 329
Query: 156 ----RIRPFAF------------RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLT 198
++ + GLPR L L+++ + +VD+ ++++ ++L
Sbjct: 330 ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLH 389
Query: 199 HNRIAQ--IESYAFAGTNFINLISLRNNPIKRI----------LVHAFSGLNDVGQIELP 246
N++ + I AF G ++ + L NN ++R+ L+ + + +G+ +
Sbjct: 390 SNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFA 449
Query: 247 ----------SGIRTIEPQ----AFAGLEGIGVLELAFMDLPSLLPDTFHGLIR-VGRLS 291
S R PQ AF L + L+L+ L +L P GL R V L
Sbjct: 450 TTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPP----GLPRNVHVLK 505
Query: 292 LRESDLGIIKVGSFDGLQHVDTLEICNNKI--DGIEELSLVQNNSVRVFKLTGNHMLESP 349
++ ++L + G+ G+ + L + +N++ + + V +++ + GN + E P
Sbjct: 506 VKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIP 565
Query: 350 EAVVLEVENIIIRGNHL 366
E + +E + ++ N +
Sbjct: 566 EGLPESLEYLYLQNNKI 582
Score = 37.1 bits (82), Expect = 0.13
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 5/120 (4%)
Query: 109 LRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL--TRIRPFAFRGLP 166
L +P GL +V L + R +L L A A + QLR L L + L + P A+ L
Sbjct: 490 LHTLPPGLPRNVHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLA 549
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
L+ L I L + +++ + L +N+I+ + + AF T + I LR N +
Sbjct: 550 HLQLLDIAGNQLTEIPE---GLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKL 606
>BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein.
Length = 402
Score = 65.7 bits (153), Expect = 3e-10
Identities = 63/230 (27%), Positives = 109/230 (47%), Gaps = 15/230 (6%)
Query: 105 NSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTR--IRPFAF 162
+S L VP+GL S+ L L + +R + ++ +R L L L + L I P AF
Sbjct: 85 SSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 144
Query: 163 RGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
+GL RL +++ + L V S + + ++++ HN+I I FA T F+ ++L
Sbjct: 145 QGLKRLHTVHLYNNALERVPS---GLPRRVRTLMILHNQITGIGREDFATTYFLEELNLS 201
Query: 223 NNPIKRILVH--AFSGLNDVGQIELPSG-IRTIEPQAFAGL-EGIGVLELAFMDLPSLLP 278
N I VH AF L + ++L + T+ P GL + VL++ +L +L
Sbjct: 202 YNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPP----GLPRNVHVLKVKRNELAALAR 257
Query: 279 DTFHGLIRVGRLSLRESDLGIIKVG--SFDGLQHVDTLEICNNKIDGIEE 326
G+ ++ L L + L +G ++ L H+ L+I N++ I E
Sbjct: 258 GALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE 307
Score = 37.9 bits (84), Expect = 0.073
Identities = 69/317 (21%), Positives = 136/317 (42%), Gaps = 56/317 (17%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT------ 155
++ +S LR VP L P++ +L L L + AF+ L LR L L LT
Sbjct: 11 LILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDN 70
Query: 156 ----RIRPFAF------------RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLT 198
++ + GLPR L L+++ + +VD+ ++++ ++L
Sbjct: 71 ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLH 130
Query: 199 HNRIAQ--IESYAFAGTNFINLISLRNNPIKRI----------LVHAFSGLNDVGQIELP 246
N++ + I AF G ++ + L NN ++R+ L+ + + +G+ +
Sbjct: 131 SNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFA 190
Query: 247 ----------SGIRTIEPQ----AFAGLEGIGVLELAFMDLPSLLPDTFHGLIR-VGRLS 291
S R PQ AF L + L+L+ L +L P GL R V L
Sbjct: 191 TTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPP----GLPRNVHVLK 246
Query: 292 LRESDLGIIKVGSFDGLQHVDTLEICNNKI--DGIEELSLVQNNSVRVFKLTGNHMLESP 349
++ ++L + G+ G+ + L + +N++ + + V +++ + GN + E P
Sbjct: 247 VKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIP 306
Query: 350 EAVVLEVENIIIRGNHL 366
E + +E + ++ N +
Sbjct: 307 EGLPESLEYLYLQNNKI 323
Score = 37.1 bits (82), Expect = 0.13
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 5/120 (4%)
Query: 109 LRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL--TRIRPFAFRGLP 166
L +P GL +V L + R +L L A A + QLR L L + L + P A+ L
Sbjct: 231 LHTLPPGLPRNVHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLA 290
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
L+ L I L + +++ + L +N+I+ + + AF T + I LR N +
Sbjct: 291 HLQLLDIAGNQLTEIPE---GLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKL 347
Score = 31.9 bits (69), Expect = 4.8
Identities = 43/217 (19%), Positives = 94/217 (43%), Gaps = 18/217 (8%)
Query: 186 FAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
F N+ ++L+ N + + + + + L+NN +++I AFS L+ + ++ L
Sbjct: 2 FNGSSNVEVLILSSNFLRHVPKHLPPA---LYKLHLKNNKLEKIPPGAFSELSSLRELYL 58
Query: 246 PSGIRT---IEPQAFAGLEGIGVLELAFMDL---PSLLPDTFHGLIRVGRLSLRESDLGI 299
+ T ++ + F L + L+L+ +L P+ LP + L+ + + ++R D +
Sbjct: 59 QNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSL-VLLHLEKNAIRSVDANV 117
Query: 300 IKVGSFDGLQHVDTLEICNNKI--DGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVE 357
+ ++ ++ L + +N++ GI L+ + L N + P + V
Sbjct: 118 L-----TPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVR 172
Query: 358 NIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
++I N + GR+ F L + N SP
Sbjct: 173 TLMILHNQI-TGIGREDFATTYFLEELNLSYNRITSP 208
>AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein.
Length = 642
Score = 65.7 bits (153), Expect = 3e-10
Identities = 63/230 (27%), Positives = 109/230 (47%), Gaps = 15/230 (6%)
Query: 105 NSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTR--IRPFAF 162
+S L VP+GL S+ L L + +R + ++ +R L L L + L I P AF
Sbjct: 325 SSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 384
Query: 163 RGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
+GL RL +++ + L V S + + ++++ HN+I I FA T F+ ++L
Sbjct: 385 QGLKRLHTVHLYNNALERVPS---GLPRRVRTLMILHNQITGIGREDFATTYFLEELNLS 441
Query: 223 NNPIKRILVH--AFSGLNDVGQIELPSG-IRTIEPQAFAGL-EGIGVLELAFMDLPSLLP 278
N I VH AF L + ++L + T+ P GL + VL++ +L +L
Sbjct: 442 YNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPP----GLPRNVHVLKVKRNELAALAR 497
Query: 279 DTFHGLIRVGRLSLRESDLGIIKVG--SFDGLQHVDTLEICNNKIDGIEE 326
G+ ++ L L + L +G ++ L H+ L+I N++ I E
Sbjct: 498 GALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE 547
Score = 43.6 bits (98), Expect = 0.001
Identities = 64/301 (21%), Positives = 128/301 (42%), Gaps = 22/301 (7%)
Query: 105 NSAALRGVPSGLSPSVTQLS-LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
N RG+P +T L+ L A+ ++ + F L + A LT+I F
Sbjct: 159 NRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLP-NALISVDFAANYLTKIYGLTFG 217
Query: 164 GLPRLRELYIQHTPLAT--VDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
P LR +Y+ + LA + F N+ ++L+ N + + + + + L
Sbjct: 218 QKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA---LYKLHL 274
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSGIRT---IEPQAFAGLEGIGVLELAFMDL---PS 275
+NN +++I AFS L+ + ++ L + T ++ + F L + L+L+ +L P+
Sbjct: 275 KNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPA 334
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI--DGIEELSLVQNN 333
LP + L+ + + ++R D ++ ++ ++ L + +N++ GI L+
Sbjct: 335 GLPRSL-VLLHLEKNAIRSVDANVL-----TPIRSLEYLLLHSNQLREQGIHPLAFQGLK 388
Query: 334 SVRVFKLTGNHMLESPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
+ L N + P + V ++I N + GR+ F L + N S
Sbjct: 389 RLHTVHLYNNALERVPSGLPRRVRTLMILHNQI-TGIGREDFATTYFLEELNLSYNRITS 447
Query: 394 P 394
P
Sbjct: 448 P 448
Score = 37.9 bits (84), Expect = 0.073
Identities = 69/317 (21%), Positives = 136/317 (42%), Gaps = 56/317 (17%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT------ 155
++ +S LR VP L P++ +L L L + AF+ L LR L L LT
Sbjct: 251 LILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDN 310
Query: 156 ----RIRPFAF------------RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLT 198
++ + GLPR L L+++ + +VD+ ++++ ++L
Sbjct: 311 ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLH 370
Query: 199 HNRIAQ--IESYAFAGTNFINLISLRNNPIKRI----------LVHAFSGLNDVGQIELP 246
N++ + I AF G ++ + L NN ++R+ L+ + + +G+ +
Sbjct: 371 SNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFA 430
Query: 247 ----------SGIRTIEPQ----AFAGLEGIGVLELAFMDLPSLLPDTFHGLIR-VGRLS 291
S R PQ AF L + L+L+ L +L P GL R V L
Sbjct: 431 TTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPP----GLPRNVHVLK 486
Query: 292 LRESDLGIIKVGSFDGLQHVDTLEICNNKI--DGIEELSLVQNNSVRVFKLTGNHMLESP 349
++ ++L + G+ G+ + L + +N++ + + V +++ + GN + E P
Sbjct: 487 VKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIP 546
Query: 350 EAVVLEVENIIIRGNHL 366
E + +E + ++ N +
Sbjct: 547 EGLPESLEYLYLQNNKI 563
Score = 37.1 bits (82), Expect = 0.13
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 5/120 (4%)
Query: 109 LRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL--TRIRPFAFRGLP 166
L +P GL +V L + R +L L A A + QLR L L + L + P A+ L
Sbjct: 471 LHTLPPGLPRNVHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLA 530
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
L+ L I L + +++ + L +N+I+ + + AF T + I LR N +
Sbjct: 531 HLQLLDIAGNQLTEIPE---GLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKL 587
>AL122074-1|CAB59249.1| 333|Homo sapiens hypothetical protein
protein.
Length = 333
Score = 65.7 bits (153), Expect = 3e-10
Identities = 44/144 (30%), Positives = 71/144 (49%), Gaps = 2/144 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDA-FAHLRQLRRLALDACN 153
C + +V C++ L +PS L VT L L+ ++ VL + F L LR++ L
Sbjct: 184 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 243
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+ +R AF G ++EL + L TV F L + +++L N I + + FAG
Sbjct: 244 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGL 303
Query: 214 NFINLISLRNNPIKRILVHAFSGL 237
+ + L+SL +N I I AF+ L
Sbjct: 304 SSVRLLSLYDNRITTITPGAFTTL 327
Score = 52.0 bits (119), Expect = 4e-06
Identities = 37/125 (29%), Positives = 60/125 (48%), Gaps = 2/125 (1%)
Query: 192 ITSIVLTHNRIAQIESYA-FAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
+T + L N ++ +E+ F + I+L NN IK + AF G V ++ L +
Sbjct: 209 VTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQL 268
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
T+ + F GL G+ L L + + DTF GL V LSL ++ + I G+F L
Sbjct: 269 ETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLV 328
Query: 310 HVDTL 314
+ T+
Sbjct: 329 SLSTM 333
Score = 50.4 bits (115), Expect = 1e-05
Identities = 29/106 (27%), Positives = 53/106 (50%), Gaps = 1/106 (0%)
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F+ LP LR++ + + + V AF ++ ++LT N++ + F G + + + L
Sbjct: 228 FKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLML 287
Query: 222 RNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVL 266
R+N I + F+GL+ V + L + I TI P AF L + +
Sbjct: 288 RSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTM 333
Score = 47.2 bits (107), Expect = 1e-04
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
Query: 173 IQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH 232
I ++ + AF L+++TS+VL N+I +I F G + L+ L N I + V+
Sbjct: 13 ISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVN 72
Query: 233 AFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELA 269
F L ++ + L + ++TI FA L+ I L LA
Sbjct: 73 TFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLA 110
Score = 43.6 bits (98), Expect = 0.001
Identities = 25/95 (26%), Positives = 45/95 (47%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
I I P AF GL+ + L L + + F GL+ + L L + + ++V +F L
Sbjct: 18 ISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDL 77
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
Q+++ L + +NK+ I + S++ L N
Sbjct: 78 QNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 112
Score = 41.1 bits (92), Expect = 0.008
Identities = 28/101 (27%), Positives = 43/101 (42%)
Query: 125 LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSF 184
+S+ + + DAF L+ L L L +T I F GL L+ L + + +
Sbjct: 13 ISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVN 72
Query: 185 AFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
F LQN+ + L N++ I FA I + L NP
Sbjct: 73 TFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNP 113
Score = 38.3 bits (85), Expect = 0.055
Identities = 23/92 (25%), Positives = 43/92 (46%)
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
++ I P AF+GL L L + + + F L ++ ++L N+I + F
Sbjct: 18 ISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDL 77
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+NL+SL +N ++ I F+ L + + L
Sbjct: 78 QNLNLLSLYDNKLQTISKGLFAPLQSIQTLHL 109
Score = 35.5 bits (78), Expect = 0.39
Identities = 31/134 (23%), Positives = 61/134 (45%), Gaps = 5/134 (3%)
Query: 193 TSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRI-LVHAFSGLNDVGQIELPSG-IR 250
T + ++ ++ +I S+ ++ + L +N + + F L ++ +I L + I+
Sbjct: 189 TIVDCSNQKLVRIPSHL---PEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIK 245
Query: 251 TIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQH 310
+ AF G + L L L ++ F GL + L LR + +G + +F GL
Sbjct: 246 EVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSS 305
Query: 311 VDTLEICNNKIDGI 324
V L + +N+I I
Sbjct: 306 VRLLSLYDNRITTI 319
Score = 35.1 bits (77), Expect = 0.52
Identities = 30/145 (20%), Positives = 58/145 (40%), Gaps = 3/145 (2%)
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQN 332
+ + PD F GL + L L + + I G FDGL + L + NKI+ + +
Sbjct: 18 ISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDL 77
Query: 333 NSVRVFKLTGNHMLESPE---AVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEEN 389
++ + L N + + A + ++ + + N C+C + L +
Sbjct: 78 QNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGA 137
Query: 390 YCISPLKVRGRSLASATSGSAGCRG 414
C SP ++ + ++ S C G
Sbjct: 138 RCSSPRRLANKRISQIKSKKFRCSG 162
>AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein.
Length = 642
Score = 65.3 bits (152), Expect = 4e-10
Identities = 63/230 (27%), Positives = 109/230 (47%), Gaps = 15/230 (6%)
Query: 105 NSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTR--IRPFAF 162
+S L VP+GL S+ L L + +R + ++ +R L L L + L I P AF
Sbjct: 325 SSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 384
Query: 163 RGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
+GL RL +++ + L V S + + ++++ HN+I I FA T F+ ++L
Sbjct: 385 QGLKRLHTVHLYNNALERVPS---GLPRRVRTLMILHNQITGIGREDFATTYFLEELNLS 441
Query: 223 NNPIKRILVH--AFSGLNDVGQIELPSG-IRTIEPQAFAGL-EGIGVLELAFMDLPSLLP 278
N I VH AF L + ++L + T+ P GL + VL++ +L +L
Sbjct: 442 YNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPP----GLPRNVHVLKVKRNELAALAR 497
Query: 279 DTFHGLIRVGRLSLRESDLGIIKVG--SFDGLQHVDTLEICNNKIDGIEE 326
G+ ++ L L + L +G ++ L H+ L+I N++ I E
Sbjct: 498 GALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE 547
Score = 43.6 bits (98), Expect = 0.001
Identities = 64/301 (21%), Positives = 128/301 (42%), Gaps = 22/301 (7%)
Query: 105 NSAALRGVPSGLSPSVTQLS-LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
N RG+P +T L+ L A+ ++ + F L + A LT+I F
Sbjct: 159 NRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLP-NALISVDFAANYLTKIYGLTFG 217
Query: 164 GLPRLRELYIQHTPLAT--VDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
P LR +Y+ + LA + F N+ ++L+ N + + + + + L
Sbjct: 218 QKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA---LYKLHL 274
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSGIRT---IEPQAFAGLEGIGVLELAFMDL---PS 275
+NN +++I AFS L+ + ++ L + T ++ + F L + L+L+ +L P+
Sbjct: 275 KNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPA 334
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI--DGIEELSLVQNN 333
LP + L+ + + ++R D ++ ++ ++ L + +N++ GI L+
Sbjct: 335 GLPRSL-VLLHLEKNAIRSVDANVL-----TPIRSLEYLLLHSNQLREQGIHPLAFQGLK 388
Query: 334 SVRVFKLTGNHMLESPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
+ L N + P + V ++I N + GR+ F L + N S
Sbjct: 389 RLHTVHLYNNALERVPSGLPRRVRTLMILHNQI-TGIGREDFATTYFLEELNLSYNRITS 447
Query: 394 P 394
P
Sbjct: 448 P 448
Score = 39.1 bits (87), Expect = 0.032
Identities = 64/271 (23%), Positives = 118/271 (43%), Gaps = 32/271 (11%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT------ 155
++ +S LR VP L P++ +L L L + AF+ L LR L L LT
Sbjct: 251 LILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDN 310
Query: 156 ----RIRPFAF------------RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLT 198
++ + GLPR L L+++ + +VD+ ++++ ++L
Sbjct: 311 ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLH 370
Query: 199 HNRIAQ--IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQA 256
N++ + I AF G ++ + L NN ++R+ + + + L + I I +
Sbjct: 371 SNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTL--MILHNQITGIGRED 428
Query: 257 FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSF-DGL-QHVDTL 314
FA + L L++ + S P R RL LR DL ++ + GL ++V L
Sbjct: 429 FATTYFLEELNLSYNRITS--PQVHRDAFRKLRL-LRSLDLSGNRLHTLPPGLPRNVHVL 485
Query: 315 EICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
++ N++ + +LV +R LT N +
Sbjct: 486 KVKRNELAALARGALVGMAQLRELYLTSNRL 516
>AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 65.3 bits (152), Expect = 4e-10
Identities = 63/230 (27%), Positives = 109/230 (47%), Gaps = 15/230 (6%)
Query: 105 NSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTR--IRPFAF 162
+S L VP+GL S+ L L + +R + ++ +R L L L + L I P AF
Sbjct: 344 SSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 403
Query: 163 RGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
+GL RL +++ + L V S + + ++++ HN+I I FA T F+ ++L
Sbjct: 404 QGLKRLHTVHLYNNALERVPS---GLPRRVRTLMILHNQITGIGREDFATTYFLEELNLS 460
Query: 223 NNPIKRILVH--AFSGLNDVGQIELPSG-IRTIEPQAFAGL-EGIGVLELAFMDLPSLLP 278
N I VH AF L + ++L + T+ P GL + VL++ +L +L
Sbjct: 461 YNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPP----GLPRNVHVLKVKRNELAALAR 516
Query: 279 DTFHGLIRVGRLSLRESDLGIIKVG--SFDGLQHVDTLEICNNKIDGIEE 326
G+ ++ L L + L +G ++ L H+ L+I N++ I E
Sbjct: 517 GALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE 566
Score = 43.6 bits (98), Expect = 0.001
Identities = 64/301 (21%), Positives = 128/301 (42%), Gaps = 22/301 (7%)
Query: 105 NSAALRGVPSGLSPSVTQLS-LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
N RG+P +T L+ L A+ ++ + F L + A LT+I F
Sbjct: 178 NRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLP-NALISVDFAANYLTKIYGLTFG 236
Query: 164 GLPRLRELYIQHTPLAT--VDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
P LR +Y+ + LA + F N+ ++L+ N + + + + + L
Sbjct: 237 QKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA---LYKLHL 293
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSGIRT---IEPQAFAGLEGIGVLELAFMDL---PS 275
+NN +++I AFS L+ + ++ L + T ++ + F L + L+L+ +L P+
Sbjct: 294 KNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPA 353
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI--DGIEELSLVQNN 333
LP + L+ + + ++R D ++ ++ ++ L + +N++ GI L+
Sbjct: 354 GLPRSL-VLLHLEKNAIRSVDANVL-----TPIRSLEYLLLHSNQLREQGIHPLAFQGLK 407
Query: 334 SVRVFKLTGNHMLESPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
+ L N + P + V ++I N + GR+ F L + N S
Sbjct: 408 RLHTVHLYNNALERVPSGLPRRVRTLMILHNQI-TGIGREDFATTYFLEELNLSYNRITS 466
Query: 394 P 394
P
Sbjct: 467 P 467
Score = 39.1 bits (87), Expect = 0.032
Identities = 64/271 (23%), Positives = 118/271 (43%), Gaps = 32/271 (11%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT------ 155
++ +S LR VP L P++ +L L L + AF+ L LR L L LT
Sbjct: 270 LILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDN 329
Query: 156 ----RIRPFAF------------RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLT 198
++ + GLPR L L+++ + +VD+ ++++ ++L
Sbjct: 330 ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLH 389
Query: 199 HNRIAQ--IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQA 256
N++ + I AF G ++ + L NN ++R+ + + + L + I I +
Sbjct: 390 SNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTL--MILHNQITGIGRED 447
Query: 257 FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSF-DGL-QHVDTL 314
FA + L L++ + S P R RL LR DL ++ + GL ++V L
Sbjct: 448 FATTYFLEELNLSYNRITS--PQVHRDAFRKLRL-LRSLDLSGNRLHTLPPGLPRNVHVL 504
Query: 315 EICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
++ N++ + +LV +R LT N +
Sbjct: 505 KVKRNELAALARGALVGMAQLRELYLTSNRL 535
>BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 64.9 bits (151), Expect = 6e-10
Identities = 57/228 (25%), Positives = 101/228 (44%), Gaps = 2/228 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL S+ L L L + ++A L L+ L LDA ++ + +F GL LR L++
Sbjct: 59 SGLY-SLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWL 117
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
L + A L + ++ L NRI+ I YAF + ++ L NN I+ + H+
Sbjct: 118 DDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 177
Query: 234 FSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLR 293
F GL+++ ++L P A L + L ++ ++ F G + +
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 294 ESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLT 341
++ + + +F L + TL + N +D E L S+ + LT
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLT 284
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/214 (28%), Positives = 95/214 (44%), Gaps = 2/214 (0%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
++ LS +L L+ F HLR L L L +L+ I AF GL L+ L +Q+ L
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 180 TVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLND 239
+ + A L ++ S+ L N I+ + +F G + + + L +N + I V A + L
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPA 135
Query: 240 VGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLG 298
+ + L + I I AF L + VL L + L +F GL + L L + L
Sbjct: 136 LQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQ 195
Query: 299 IIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQN 332
V + L + L NN I I E + + N
Sbjct: 196 EFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGN 228
Score = 49.2 bits (112), Expect = 3e-05
Identities = 58/242 (23%), Positives = 106/242 (43%), Gaps = 33/242 (13%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
PS+ L L + ++ +F L LR L LD LT I A LP L+ + +
Sbjct: 86 PSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNR 145
Query: 178 LATVDSFAFAALQNITSIVLTH---NRIAQIESYAFAGTNFINLISLRNNPIKR--ILVH 232
++ + +AF QN+TS+V+ H NRI + +++F G + + + L N ++ + +
Sbjct: 146 ISHIPDYAF---QNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIR 202
Query: 233 AFSGLNDVGQIELPSGIRTIEPQAFAG---LEGIGVLE--------LAFMDLPSLLPDTF 281
L ++G + I+ I +AF G L+ I + AF LP L +
Sbjct: 203 TLGRLQELGFHN--NNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL 260
Query: 282 HGLIRVGR------------LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSL 329
+G + + L+L + + ++ G L + LE+ +N+I+ + L
Sbjct: 261 NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHR 320
Query: 330 VQ 331
Q
Sbjct: 321 CQ 322
Score = 45.6 bits (103), Expect = 4e-04
Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
LPRLR L + H + + S Q + I L HNRI +I + F+ + + + L N
Sbjct: 299 LPRLRVLELSHNQIEELPSLH--RCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Query: 225 PIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
I+ I AFS L+ + +++L T P AGL G+ L+L
Sbjct: 357 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKL 398
Score = 41.1 bits (92), Expect = 0.008
Identities = 42/163 (25%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
AF +L +L L+L+ + P +G L L + + + S L + +
Sbjct: 248 AFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLE 306
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQ 255
L+HN+I ++ S + I L++N I I FS L+ + ++L + IR+I P+
Sbjct: 307 LSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPE 364
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV---GRLSLRES 295
AF+ L + L+L L +L GL+ + G L+L ++
Sbjct: 365 AFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQA 407
Score = 40.7 bits (91), Expect = 0.010
Identities = 38/151 (25%), Positives = 69/151 (45%), Gaps = 3/151 (1%)
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQ 255
L+ N + +++ F F+ + L N + I AFSGL + + L + + I +
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 256 AFAGLEGIGVLELAFMDLPSLLPD-TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTL 314
A L + L L +L SL+P+ +F GL + L L ++ L I V + + L + +
Sbjct: 81 ALWELPSLQSLRLD-ANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 315 EICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ N+I I + + S+ V L N +
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRI 170
Score = 36.7 bits (81), Expect = 0.17
Identities = 26/88 (29%), Positives = 42/88 (47%)
Query: 263 IGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
I +L+ +L L P FH L + L L + L I +F GL + L + NN++
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 323 GIEELSLVQNNSVRVFKLTGNHMLESPE 350
GI +L + S++ +L N + PE
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPE 103
>AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor
protein.
Length = 915
Score = 64.9 bits (151), Expect = 6e-10
Identities = 57/228 (25%), Positives = 101/228 (44%), Gaps = 2/228 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL S+ L L L + ++A L L+ L LDA ++ + +F GL LR L++
Sbjct: 59 SGLY-SLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWL 117
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
L + A L + ++ L NRI+ I YAF + ++ L NN I+ + H+
Sbjct: 118 DDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 177
Query: 234 FSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLR 293
F GL+++ ++L P A L + L ++ ++ F G + +
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 294 ESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLT 341
++ + + +F L + TL + N +D E L S+ + LT
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLT 284
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/214 (28%), Positives = 95/214 (44%), Gaps = 2/214 (0%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
++ LS +L L+ F HLR L L L +L+ I AF GL L+ L +Q+ L
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 180 TVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLND 239
+ + A L ++ S+ L N I+ + +F G + + + L +N + I V A + L
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPA 135
Query: 240 VGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLG 298
+ + L + I I AF L + VL L + L +F GL + L L + L
Sbjct: 136 LQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQ 195
Query: 299 IIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQN 332
V + L + L NN I I E + + N
Sbjct: 196 EFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGN 228
Score = 49.2 bits (112), Expect = 3e-05
Identities = 58/242 (23%), Positives = 106/242 (43%), Gaps = 33/242 (13%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
PS+ L L + ++ +F L LR L LD LT I A LP L+ + +
Sbjct: 86 PSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNR 145
Query: 178 LATVDSFAFAALQNITSIVLTH---NRIAQIESYAFAGTNFINLISLRNNPIKR--ILVH 232
++ + +AF QN+TS+V+ H NRI + +++F G + + + L N ++ + +
Sbjct: 146 ISHIPDYAF---QNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIR 202
Query: 233 AFSGLNDVGQIELPSGIRTIEPQAFAG---LEGIGVLE--------LAFMDLPSLLPDTF 281
L ++G + I+ I +AF G L+ I + AF LP L +
Sbjct: 203 TLGRLQELGFHN--NNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL 260
Query: 282 HGLIRVGR------------LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSL 329
+G + + L+L + + ++ G L + LE+ +N+I+ + L
Sbjct: 261 NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHR 320
Query: 330 VQ 331
Q
Sbjct: 321 CQ 322
Score = 45.6 bits (103), Expect = 4e-04
Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
LPRLR L + H + + S Q + I L HNRI +I + F+ + + + L N
Sbjct: 299 LPRLRVLELSHNQIEELPSLH--RCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Query: 225 PIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
I+ I AFS L+ + +++L T P AGL G+ L+L
Sbjct: 357 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKL 398
Score = 41.1 bits (92), Expect = 0.008
Identities = 42/163 (25%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
AF +L +L L+L+ + P +G L L + + + S L + +
Sbjct: 248 AFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLE 306
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQ 255
L+HN+I ++ S + I L++N I I FS L+ + ++L + IR+I P+
Sbjct: 307 LSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPE 364
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV---GRLSLRES 295
AF+ L + L+L L +L GL+ + G L+L ++
Sbjct: 365 AFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQA 407
Score = 40.7 bits (91), Expect = 0.010
Identities = 38/151 (25%), Positives = 69/151 (45%), Gaps = 3/151 (1%)
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQ 255
L+ N + +++ F F+ + L N + I AFSGL + + L + + I +
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 256 AFAGLEGIGVLELAFMDLPSLLPD-TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTL 314
A L + L L +L SL+P+ +F GL + L L ++ L I V + + L + +
Sbjct: 81 ALWELPSLQSLRLD-ANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 315 EICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ N+I I + + S+ V L N +
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRI 170
Score = 36.7 bits (81), Expect = 0.17
Identities = 26/88 (29%), Positives = 42/88 (47%)
Query: 263 IGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
I +L+ +L L P FH L + L L + L I +F GL + L + NN++
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 323 GIEELSLVQNNSVRVFKLTGNHMLESPE 350
GI +L + S++ +L N + PE
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPE 103
>AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 409
Score = 64.9 bits (151), Expect = 6e-10
Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 1/157 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R RL L+ N+TRI F GL +LR L + + V+ AF ++ + + L N+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGL 260
+ + F ++ + L N I+ I AF G D+ ++L I IE AF L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
G+ VL L ++ ++ +F+ + ++ L + L
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 54.8 bits (126), Expect = 6e-07
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+N + L N I +I FAG + ++ L N I + AF + ++ ++ L
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQ 120
Query: 250 RTIEPQA-FAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
+ P+ F + + L+L+ + ++ F G + L L ++ + I+ G+F L
Sbjct: 121 LHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRAL 180
Query: 309 QHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ ++ L + NN I I S +R F+L NH+
Sbjct: 181 RGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 54.4 bits (125), Expect = 8e-07
Identities = 48/201 (23%), Positives = 81/201 (40%), Gaps = 4/201 (1%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI + F+GL + ++L I +E AF ++ + L L L L
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F + RL L E+ + I +F G + L++ N+I IEE + + V
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEV 185
Query: 338 FKLTGNHMLESPEAV---VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
L N++ P + + ++ + NHL C+C + L C P
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGP 245
Query: 395 LKVRGRSLASATSGSAGCRGE 415
+RG ++A C G+
Sbjct: 246 ASLRGLNVAEVQKSEFSCSGQ 266
Score = 45.2 bits (102), Expect = 5e-04
Identities = 30/125 (24%), Positives = 55/125 (44%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + + AF +++L RL L+ L + F+ L L + + +
Sbjct: 90 LQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP 149
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQ 242
AF ++ ++ L N+I+ IE AF + +++L NN I I V +F+ + +
Sbjct: 150 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 209
Query: 243 IELPS 247
L S
Sbjct: 210 FRLHS 214
Score = 44.4 bits (100), Expect = 8e-04
Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +V C L +P+ L ++T++ L ++ + AF+ R+LRR+ L
Sbjct: 285 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQ 344
Query: 154 LTRIRPFAFRGLPRLRELY 172
+ I P AF+GL L L+
Sbjct: 345 IAEIAPDAFQGLRSLNSLH 363
>AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 64.9 bits (151), Expect = 6e-10
Identities = 57/228 (25%), Positives = 101/228 (44%), Gaps = 2/228 (0%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL S+ L L L + ++A L L+ L LDA ++ + +F GL LR L++
Sbjct: 59 SGLY-SLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWL 117
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
L + A L + ++ L NRI+ I YAF + ++ L NN I+ + H+
Sbjct: 118 DDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 177
Query: 234 FSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLR 293
F GL+++ ++L P A L + L ++ ++ F G + +
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 294 ESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLT 341
++ + + +F L + TL + N +D E L S+ + LT
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSL-NGAMDIQEFPDLKGTTSLEILTLT 284
Score = 64.1 bits (149), Expect = 1e-09
Identities = 60/214 (28%), Positives = 95/214 (44%), Gaps = 2/214 (0%)
Query: 120 VTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLA 179
++ LS +L L+ F HLR L L L +L+ I AF GL L+ L +Q+ L
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 180 TVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLND 239
+ + A L ++ S+ L N I+ + +F G + + + L +N + I V A + L
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPA 135
Query: 240 VGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLG 298
+ + L + I I AF L + VL L + L +F GL + L L + L
Sbjct: 136 LQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQ 195
Query: 299 IIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQN 332
V + L + L NN I I E + + N
Sbjct: 196 EFPV-AIRTLGRLQELGFHNNNIKAIPEKAFMGN 228
Score = 49.2 bits (112), Expect = 3e-05
Identities = 58/242 (23%), Positives = 106/242 (43%), Gaps = 33/242 (13%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
PS+ L L + ++ +F L LR L LD LT I A LP L+ + +
Sbjct: 86 PSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNR 145
Query: 178 LATVDSFAFAALQNITSIVLTH---NRIAQIESYAFAGTNFINLISLRNNPIKR--ILVH 232
++ + +AF QN+TS+V+ H NRI + +++F G + + + L N ++ + +
Sbjct: 146 ISHIPDYAF---QNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIR 202
Query: 233 AFSGLNDVGQIELPSGIRTIEPQAFAG---LEGIGVLE--------LAFMDLPSLLPDTF 281
L ++G + I+ I +AF G L+ I + AF LP L +
Sbjct: 203 TLGRLQELGFHN--NNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSL 260
Query: 282 HGLIRVGR------------LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSL 329
+G + + L+L + + ++ G L + LE+ +N+I+ + L
Sbjct: 261 NGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHR 320
Query: 330 VQ 331
Q
Sbjct: 321 CQ 322
Score = 45.6 bits (103), Expect = 4e-04
Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
LPRLR L + H + + S Q + I L HNRI +I + F+ + + + L N
Sbjct: 299 LPRLRVLELSHNQIEELPSLH--RCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 356
Query: 225 PIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
I+ I AFS L+ + +++L T P AGL G+ L+L
Sbjct: 357 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKL 398
Score = 41.1 bits (92), Expect = 0.008
Identities = 42/163 (25%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
AF +L +L L+L+ + P +G L L + + + S L + +
Sbjct: 248 AFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLE 306
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQ 255
L+HN+I ++ S + I L++N I I FS L+ + ++L + IR+I P+
Sbjct: 307 LSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPE 364
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV---GRLSLRES 295
AF+ L + L+L L +L GL+ + G L+L ++
Sbjct: 365 AFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQA 407
Score = 40.7 bits (91), Expect = 0.010
Identities = 38/151 (25%), Positives = 69/151 (45%), Gaps = 3/151 (1%)
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQ 255
L+ N + +++ F F+ + L N + I AFSGL + + L + + I +
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 256 AFAGLEGIGVLELAFMDLPSLLPD-TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTL 314
A L + L L +L SL+P+ +F GL + L L ++ L I V + + L + +
Sbjct: 81 ALWELPSLQSLRLD-ANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 315 EICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ N+I I + + S+ V L N +
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRI 170
Score = 36.7 bits (81), Expect = 0.17
Identities = 26/88 (29%), Positives = 42/88 (47%)
Query: 263 IGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
I +L+ +L L P FH L + L L + L I +F GL + L + NN++
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 323 GIEELSLVQNNSVRVFKLTGNHMLESPE 350
GI +L + S++ +L N + PE
Sbjct: 76 GIPAEALWELPSLQSLRLDANLISLVPE 103
>U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3
protein.
Length = 904
Score = 64.5 bits (150), Expect = 7e-10
Identities = 50/199 (25%), Positives = 89/199 (44%), Gaps = 5/199 (2%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+ L VP L ++T L+L+ LR L + F QL L + ++++ P +
Sbjct: 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
LP L+ L +QH L+ + FA N+T + L N I +I++ F + + L +
Sbjct: 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
Query: 224 NPIKRILVHAFSGLNDVGQIELPS----GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
N + + L ++ ++ L + +++ E FA + LEL+ + P
Sbjct: 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPG 215
Query: 280 TFHGLIRVGRLSLRESDLG 298
FH + R+ L L LG
Sbjct: 216 CFHAIGRLFGLFLNNVQLG 234
Score = 53.6 bits (123), Expect = 1e-06
Identities = 54/214 (25%), Positives = 105/214 (49%), Gaps = 8/214 (3%)
Query: 116 LSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQH 175
L S T+ S+S A L + +F L+ L L ++ ++ I+ F GL L+ L + +
Sbjct: 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
Query: 176 --TPLATVDSFAFAALQN--ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILV 231
T L T+ + F +L + + + LT N+I++IES AF+ + ++ L N I + L
Sbjct: 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
Query: 232 -HAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL--LPDTFHGLIRV 287
+ GL ++ +I L + + +FA + + L L + L ++ P F L +
Sbjct: 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 288 GRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L L +++ I +GL+ ++ L++ +N +
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
Score = 46.8 bits (106), Expect = 2e-04
Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 16/174 (9%)
Query: 168 LRELYIQHTPLATVDSFAFAALQ--NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+R L + ++ L+T + F L+ N+T + L++N + + + +FA + L N
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 226 IKRILVHAFSGLNDVGQIELP----------SGIRTIEPQAFAGLEGIGVLELAFMDLPS 275
I+ + H+ GL +V + L + + I+ +F L+ + L + D+P
Sbjct: 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
Query: 276 LLPDTFHGLIRVGRLSLRES--DLGIIKVGSFDGLQH--VDTLEICNNKIDGIE 325
+ + F GLI + LSL S L + +F L H + L + NKI IE
Sbjct: 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
Score = 44.0 bits (99), Expect = 0.001
Identities = 36/160 (22%), Positives = 73/160 (45%), Gaps = 3/160 (1%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
NIT + LTHN++ ++ + F + + + + N I ++ L + + L +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
+ + FA + L L + + + F + L L + L K+G+ L+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 310 HVDTLEICNNKIDGI--EELSLVQNNSVRVFKLTGNHMLE 347
++ L + NNKI + EEL + N+S++ +L+ N + E
Sbjct: 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
>DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3
isoform NT2-N protein.
Length = 904
Score = 64.5 bits (150), Expect = 7e-10
Identities = 50/199 (25%), Positives = 89/199 (44%), Gaps = 5/199 (2%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+ L VP L ++T L+L+ LR L + F QL L + ++++ P +
Sbjct: 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
LP L+ L +QH L+ + FA N+T + L N I +I++ F + + L +
Sbjct: 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
Query: 224 NPIKRILVHAFSGLNDVGQIELPS----GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
N + + L ++ ++ L + +++ E FA + LEL+ + P
Sbjct: 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPG 215
Query: 280 TFHGLIRVGRLSLRESDLG 298
FH + R+ L L LG
Sbjct: 216 CFHAIGRLFGLFLNNVQLG 234
Score = 53.6 bits (123), Expect = 1e-06
Identities = 54/214 (25%), Positives = 105/214 (49%), Gaps = 8/214 (3%)
Query: 116 LSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQH 175
L S T+ S+S A L + +F L+ L L ++ ++ I+ F GL L+ L + +
Sbjct: 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
Query: 176 --TPLATVDSFAFAALQN--ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILV 231
T L T+ + F +L + + + LT N+I++IES AF+ + ++ L N I + L
Sbjct: 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
Query: 232 -HAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL--LPDTFHGLIRV 287
+ GL ++ +I L + + +FA + + L L + L ++ P F L +
Sbjct: 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 288 GRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L L +++ I +GL+ ++ L++ +N +
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
Score = 46.8 bits (106), Expect = 2e-04
Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 16/174 (9%)
Query: 168 LRELYIQHTPLATVDSFAFAALQ--NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+R L + ++ L+T + F L+ N+T + L++N + + + +FA + L N
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 226 IKRILVHAFSGLNDVGQIELP----------SGIRTIEPQAFAGLEGIGVLELAFMDLPS 275
I+ + H+ GL +V + L + + I+ +F L+ + L + D+P
Sbjct: 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
Query: 276 LLPDTFHGLIRVGRLSLRES--DLGIIKVGSFDGLQH--VDTLEICNNKIDGIE 325
+ + F GLI + LSL S L + +F L H + L + NKI IE
Sbjct: 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
Score = 44.0 bits (99), Expect = 0.001
Identities = 36/160 (22%), Positives = 73/160 (45%), Gaps = 3/160 (1%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
NIT + LTHN++ ++ + F + + + + N I ++ L + + L +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
+ + FA + L L + + + F + L L + L K+G+ L+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 310 HVDTLEICNNKIDGI--EELSLVQNNSVRVFKLTGNHMLE 347
++ L + NNKI + EEL + N+S++ +L+ N + E
Sbjct: 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
>BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 64.5 bits (150), Expect = 7e-10
Identities = 50/199 (25%), Positives = 89/199 (44%), Gaps = 5/199 (2%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+ L VP L ++T L+L+ LR L + F QL L + ++++ P +
Sbjct: 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
LP L+ L +QH L+ + FA N+T + L N I +I++ F + + L +
Sbjct: 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
Query: 224 NPIKRILVHAFSGLNDVGQIELPS----GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
N + + L ++ ++ L + +++ E FA + LEL+ + P
Sbjct: 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPG 215
Query: 280 TFHGLIRVGRLSLRESDLG 298
FH + R+ L L LG
Sbjct: 216 CFHAIGRLFGLFLNNVQLG 234
Score = 53.6 bits (123), Expect = 1e-06
Identities = 54/214 (25%), Positives = 105/214 (49%), Gaps = 8/214 (3%)
Query: 116 LSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQH 175
L S T+ S+S A L + +F L+ L L ++ ++ I+ F GL L+ L + +
Sbjct: 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
Query: 176 --TPLATVDSFAFAALQN--ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILV 231
T L T+ + F +L + + + LT N+I++IES AF+ + ++ L N I + L
Sbjct: 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
Query: 232 -HAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL--LPDTFHGLIRV 287
+ GL ++ +I L + + +FA + + L L + L ++ P F L +
Sbjct: 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 288 GRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L L +++ I +GL+ ++ L++ +N +
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
Score = 46.8 bits (106), Expect = 2e-04
Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 16/174 (9%)
Query: 168 LRELYIQHTPLATVDSFAFAALQ--NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+R L + ++ L+T + F L+ N+T + L++N + + + +FA + L N
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 226 IKRILVHAFSGLNDVGQIELP----------SGIRTIEPQAFAGLEGIGVLELAFMDLPS 275
I+ + H+ GL +V + L + + I+ +F L+ + L + D+P
Sbjct: 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
Query: 276 LLPDTFHGLIRVGRLSLRES--DLGIIKVGSFDGLQH--VDTLEICNNKIDGIE 325
+ + F GLI + LSL S L + +F L H + L + NKI IE
Sbjct: 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
Score = 44.0 bits (99), Expect = 0.001
Identities = 36/160 (22%), Positives = 73/160 (45%), Gaps = 3/160 (1%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
NIT + LTHN++ ++ + F + + + + N I ++ L + + L +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
+ + FA + L L + + + F + L L + L K+G+ L+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 310 HVDTLEICNNKIDGI--EELSLVQNNSVRVFKLTGNHMLE 347
++ L + NNKI + EEL + N+S++ +L+ N + E
Sbjct: 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
>BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 64.5 bits (150), Expect = 7e-10
Identities = 50/199 (25%), Positives = 89/199 (44%), Gaps = 5/199 (2%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+ L VP L ++T L+L+ LR L + F QL L + ++++ P +
Sbjct: 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
LP L+ L +QH L+ + FA N+T + L N I +I++ F + + L +
Sbjct: 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
Query: 224 NPIKRILVHAFSGLNDVGQIELPS----GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
N + + L ++ ++ L + +++ E FA + LEL+ + P
Sbjct: 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPG 215
Query: 280 TFHGLIRVGRLSLRESDLG 298
FH + R+ L L LG
Sbjct: 216 CFHAIGRLFGLFLNNVQLG 234
Score = 53.6 bits (123), Expect = 1e-06
Identities = 54/214 (25%), Positives = 105/214 (49%), Gaps = 8/214 (3%)
Query: 116 LSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQH 175
L S T+ S+S A L + +F L+ L L ++ ++ I+ F GL L+ L + +
Sbjct: 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
Query: 176 --TPLATVDSFAFAALQN--ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILV 231
T L T+ + F +L + + + LT N+I++IES AF+ + ++ L N I + L
Sbjct: 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
Query: 232 -HAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL--LPDTFHGLIRV 287
+ GL ++ +I L + + +FA + + L L + L ++ P F L +
Sbjct: 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 288 GRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L L +++ I +GL+ ++ L++ +N +
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
Score = 46.8 bits (106), Expect = 2e-04
Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 16/174 (9%)
Query: 168 LRELYIQHTPLATVDSFAFAALQ--NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+R L + ++ L+T + F L+ N+T + L++N + + + +FA + L N
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 226 IKRILVHAFSGLNDVGQIELP----------SGIRTIEPQAFAGLEGIGVLELAFMDLPS 275
I+ + H+ GL +V + L + + I+ +F L+ + L + D+P
Sbjct: 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
Query: 276 LLPDTFHGLIRVGRLSLRES--DLGIIKVGSFDGLQH--VDTLEICNNKIDGIE 325
+ + F GLI + LSL S L + +F L H + L + NKI IE
Sbjct: 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
Score = 44.0 bits (99), Expect = 0.001
Identities = 36/160 (22%), Positives = 73/160 (45%), Gaps = 3/160 (1%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
NIT + LTHN++ ++ + F + + + + N I ++ L + + L +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
+ + FA + L L + + + F + L L + L K+G+ L+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 310 HVDTLEICNNKIDGI--EELSLVQNNSVRVFKLTGNHMLE 347
++ L + NNKI + EEL + N+S++ +L+ N + E
Sbjct: 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
>BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 64.5 bits (150), Expect = 7e-10
Identities = 50/199 (25%), Positives = 89/199 (44%), Gaps = 5/199 (2%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+ L VP L ++T L+L+ LR L + F QL L + ++++ P +
Sbjct: 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
LP L+ L +QH L+ + FA N+T + L N I +I++ F + + L +
Sbjct: 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
Query: 224 NPIKRILVHAFSGLNDVGQIELPS----GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
N + + L ++ ++ L + +++ E FA + LEL+ + P
Sbjct: 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPG 215
Query: 280 TFHGLIRVGRLSLRESDLG 298
FH + R+ L L LG
Sbjct: 216 CFHAIGRLFGLFLNNVQLG 234
Score = 53.6 bits (123), Expect = 1e-06
Identities = 54/214 (25%), Positives = 105/214 (49%), Gaps = 8/214 (3%)
Query: 116 LSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQH 175
L S T+ S+S A L + +F L+ L L ++ ++ I+ F GL L+ L + +
Sbjct: 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
Query: 176 --TPLATVDSFAFAALQN--ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILV 231
T L T+ + F +L + + + LT N+I++IES AF+ + ++ L N I + L
Sbjct: 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
Query: 232 -HAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL--LPDTFHGLIRV 287
+ GL ++ +I L + + +FA + + L L + L ++ P F L +
Sbjct: 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 288 GRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L L +++ I +GL+ ++ L++ +N +
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
Score = 46.8 bits (106), Expect = 2e-04
Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 16/174 (9%)
Query: 168 LRELYIQHTPLATVDSFAFAALQ--NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+R L + ++ L+T + F L+ N+T + L++N + + + +FA + L N
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 226 IKRILVHAFSGLNDVGQIELP----------SGIRTIEPQAFAGLEGIGVLELAFMDLPS 275
I+ + H+ GL +V + L + + I+ +F L+ + L + D+P
Sbjct: 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
Query: 276 LLPDTFHGLIRVGRLSLRES--DLGIIKVGSFDGLQH--VDTLEICNNKIDGIE 325
+ + F GLI + LSL S L + +F L H + L + NKI IE
Sbjct: 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
Score = 44.0 bits (99), Expect = 0.001
Identities = 36/160 (22%), Positives = 73/160 (45%), Gaps = 3/160 (1%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
NIT + LTHN++ ++ + F + + + + N I ++ L + + L +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
+ + FA + L L + + + F + L L + L K+G+ L+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 310 HVDTLEICNNKIDGI--EELSLVQNNSVRVFKLTGNHMLE 347
++ L + NNKI + EEL + N+S++ +L+ N + E
Sbjct: 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
>BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 64.5 bits (150), Expect = 7e-10
Identities = 50/199 (25%), Positives = 89/199 (44%), Gaps = 5/199 (2%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+ L VP L ++T L+L+ LR L + F QL L + ++++ P +
Sbjct: 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
LP L+ L +QH L+ + FA N+T + L N I +I++ F + + L +
Sbjct: 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
Query: 224 NPIKRILVHAFSGLNDVGQIELPS----GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
N + + L ++ ++ L + +++ E FA + LEL+ + P
Sbjct: 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPG 215
Query: 280 TFHGLIRVGRLSLRESDLG 298
FH + R+ L L LG
Sbjct: 216 CFHAIGRLFGLFLNNVQLG 234
Score = 53.6 bits (123), Expect = 1e-06
Identities = 54/214 (25%), Positives = 105/214 (49%), Gaps = 8/214 (3%)
Query: 116 LSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQH 175
L S T+ S+S A L + +F L+ L L ++ ++ I+ F GL L+ L + +
Sbjct: 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
Query: 176 --TPLATVDSFAFAALQN--ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILV 231
T L T+ + F +L + + + LT N+I++IES AF+ + ++ L N I + L
Sbjct: 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
Query: 232 -HAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL--LPDTFHGLIRV 287
+ GL ++ +I L + + +FA + + L L + L ++ P F L +
Sbjct: 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 288 GRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L L +++ I +GL+ ++ L++ +N +
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
Score = 46.8 bits (106), Expect = 2e-04
Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 16/174 (9%)
Query: 168 LRELYIQHTPLATVDSFAFAALQ--NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+R L + ++ L+T + F L+ N+T + L++N + + + +FA + L N
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 226 IKRILVHAFSGLNDVGQIELP----------SGIRTIEPQAFAGLEGIGVLELAFMDLPS 275
I+ + H+ GL +V + L + + I+ +F L+ + L + D+P
Sbjct: 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
Query: 276 LLPDTFHGLIRVGRLSLRES--DLGIIKVGSFDGLQH--VDTLEICNNKIDGIE 325
+ + F GLI + LSL S L + +F L H + L + NKI IE
Sbjct: 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
Score = 44.0 bits (99), Expect = 0.001
Identities = 36/160 (22%), Positives = 73/160 (45%), Gaps = 3/160 (1%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
NIT + LTHN++ ++ + F + + + + N I ++ L + + L +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
+ + FA + L L + + + F + L L + L K+G+ L+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 310 HVDTLEICNNKIDGI--EELSLVQNNSVRVFKLTGNHMLE 347
++ L + NNKI + EEL + N+S++ +L+ N + E
Sbjct: 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
>BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein.
Length = 870
Score = 64.5 bits (150), Expect = 7e-10
Identities = 50/199 (25%), Positives = 89/199 (44%), Gaps = 5/199 (2%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C+ L VP L ++T L+L+ LR L + F QL L + ++++ P +
Sbjct: 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRN 223
LP L+ L +QH L+ + FA N+T + L N I +I++ F + + L +
Sbjct: 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
Query: 224 NPIKRILVHAFSGLNDVGQIELPS----GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
N + + L ++ ++ L + +++ E FA + LEL+ + P
Sbjct: 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPG 215
Query: 280 TFHGLIRVGRLSLRESDLG 298
FH + R+ L L LG
Sbjct: 216 CFHAIGRLFGLFLNNVQLG 234
Score = 53.6 bits (123), Expect = 1e-06
Identities = 54/214 (25%), Positives = 105/214 (49%), Gaps = 8/214 (3%)
Query: 116 LSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQH 175
L S T+ S+S A L + +F L+ L L ++ ++ I+ F GL L+ L + +
Sbjct: 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
Query: 176 --TPLATVDSFAFAALQN--ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILV 231
T L T+ + F +L + + + LT N+I++IES AF+ + ++ L N I + L
Sbjct: 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
Query: 232 -HAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMDLPSL--LPDTFHGLIRV 287
+ GL ++ +I L + + +FA + + L L + L ++ P F L +
Sbjct: 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 288 GRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
L L +++ I +GL+ ++ L++ +N +
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
Score = 46.8 bits (106), Expect = 2e-04
Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 16/174 (9%)
Query: 168 LRELYIQHTPLATVDSFAFAALQ--NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
+R L + ++ L+T + F L+ N+T + L++N + + + +FA + L N
Sbjct: 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
Query: 226 IKRILVHAFSGLNDVGQIELP----------SGIRTIEPQAFAGLEGIGVLELAFMDLPS 275
I+ + H+ GL +V + L + + I+ +F L+ + L + D+P
Sbjct: 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
Query: 276 LLPDTFHGLIRVGRLSLRES--DLGIIKVGSFDGLQH--VDTLEICNNKIDGIE 325
+ + F GLI + LSL S L + +F L H + L + NKI IE
Sbjct: 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
Score = 44.0 bits (99), Expect = 0.001
Identities = 36/160 (22%), Positives = 73/160 (45%), Gaps = 3/160 (1%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-I 249
NIT + LTHN++ ++ + F + + + + N I ++ L + + L +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
+ + FA + L L + + + F + L L + L K+G+ L+
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
Query: 310 HVDTLEICNNKIDGI--EELSLVQNNSVRVFKLTGNHMLE 347
++ L + NNKI + EEL + N+S++ +L+ N + E
Sbjct: 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
>AY358316-1|AAQ88682.1| 745|Homo sapiens FPLR1885 protein.
Length = 745
Score = 64.5 bits (150), Expect = 7e-10
Identities = 42/145 (28%), Positives = 71/145 (48%), Gaps = 6/145 (4%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C LR VP GL +VT LSLS + VLR AFA + Q+ L L + + P A
Sbjct: 37 CAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALA 96
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVL---THNRIAQIESYAFAGTNFINLIS 220
L +L+ L + H + SF ++ L+N++++ L HNR+ + A + +
Sbjct: 97 VLSQLKNLDLSHN---FISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLR 153
Query: 221 LRNNPIKRILVHAFSGLNDVGQIEL 245
+ NN ++ + F L+ + ++L
Sbjct: 154 INNNRLRTLAPGTFDALSALSHLQL 178
Score = 34.3 bits (75), Expect = 0.90
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
+ +SL N I + AF+ + V + L +RT+EP A A L + L+L+ +
Sbjct: 53 VTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFIS 112
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
S L + L + + LG + + L + +L I NN++
Sbjct: 113 SFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRL 159
>AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein.
Length = 613
Score = 64.5 bits (150), Expect = 7e-10
Identities = 60/228 (26%), Positives = 105/228 (46%), Gaps = 11/228 (4%)
Query: 105 NSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTR--IRPFAF 162
+S L VP+GL S+ L L + +R + ++ +R L L L + L I P AF
Sbjct: 296 SSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 355
Query: 163 RGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
+GL RL +++ + L V S + + ++++ HN+I I FA T F+ ++L
Sbjct: 356 QGLKRLHTVHLYNNALERVPS---GLPRRVRTLMILHNQITGIGREDFATTYFLEELNLS 412
Query: 223 NNPIKRILVH--AFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDT 280
N I VH AF L + ++L + P + VL++ +L +L
Sbjct: 413 YNRITSPQVHRDAFRKLRLLRSLDLSGNRLHMLPPGLP--RNVHVLKVKRNELAALARGA 470
Query: 281 FHGLIRVGRLSLRESDLGIIKVG--SFDGLQHVDTLEICNNKIDGIEE 326
G+ ++ L L + L +G ++ L H+ L+I N++ I E
Sbjct: 471 LAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE 518
Score = 43.6 bits (98), Expect = 0.001
Identities = 64/301 (21%), Positives = 128/301 (42%), Gaps = 22/301 (7%)
Query: 105 NSAALRGVPSGLSPSVTQLS-LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
N RG+P +T L+ L A+ ++ + F L + A LT+I F
Sbjct: 130 NRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLP-NALISVDFAANYLTKIYGLTFG 188
Query: 164 GLPRLRELYIQHTPLAT--VDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
P LR +Y+ + LA + F N+ ++L+ N + + + + + L
Sbjct: 189 QKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA---LYKLHL 245
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPSGIRT---IEPQAFAGLEGIGVLELAFMDL---PS 275
+NN +++I AFS L+ + ++ L + T ++ + F L + L+L+ +L P+
Sbjct: 246 KNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPA 305
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI--DGIEELSLVQNN 333
LP + L+ + + ++R D ++ ++ ++ L + +N++ GI L+
Sbjct: 306 GLPRSL-VLLHLEKNAIRSVDANVL-----TPIRSLEYLLLHSNQLREQGIHPLAFQGLK 359
Query: 334 SVRVFKLTGNHMLESPEAVVLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCIS 393
+ L N + P + V ++I N + GR+ F L + N S
Sbjct: 360 RLHTVHLYNNALERVPSGLPRRVRTLMILHNQI-TGIGREDFATTYFLEELNLSYNRITS 418
Query: 394 P 394
P
Sbjct: 419 P 419
Score = 37.1 bits (82), Expect = 0.13
Identities = 60/271 (22%), Positives = 116/271 (42%), Gaps = 32/271 (11%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT------ 155
++ +S LR VP L P++ +L L L + AF+ L LR L L LT
Sbjct: 222 LILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDN 281
Query: 156 ----RIRPFAF------------RGLPR-LRELYIQHTPLATVDSFAFAALQNITSIVLT 198
++ + GLPR L L+++ + +VD+ ++++ ++L
Sbjct: 282 ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLH 341
Query: 199 HNRIAQ--IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQA 256
N++ + I AF G ++ + L NN ++R+ + + + L + I I +
Sbjct: 342 SNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTL--MILHNQITGIGRED 399
Query: 257 FAGLEGIGVLELAF--MDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTL 314
FA + L L++ + P + D F L + L L + L ++ G ++V L
Sbjct: 400 FATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHMLPPGL---PRNVHVL 456
Query: 315 EICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
++ N++ + +L +R LT N +
Sbjct: 457 KVKRNELAALARGALAGMAQLRELYLTSNRL 487
Score = 36.7 bits (81), Expect = 0.17
Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 5/120 (4%)
Query: 109 LRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL--TRIRPFAFRGLP 166
L +P GL +V L + R +L L A A + QLR L L + L + P A+ L
Sbjct: 442 LHMLPPGLPRNVHVLKVKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLA 501
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
L+ L I L + +++ + L +N+I+ + + AF T + I LR N +
Sbjct: 502 HLQLLDIAGNQLTEIPE---GLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKL 558
>AB040898-1|BAA95989.2| 785|Homo sapiens KIAA1465 protein protein.
Length = 785
Score = 64.5 bits (150), Expect = 7e-10
Identities = 42/145 (28%), Positives = 71/145 (48%), Gaps = 6/145 (4%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C LR VP GL +VT LSLS + VLR AFA + Q+ L L + + P A
Sbjct: 77 CAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALA 136
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVL---THNRIAQIESYAFAGTNFINLIS 220
L +L+ L + H + SF ++ L+N++++ L HNR+ + A + +
Sbjct: 137 VLSQLKNLDLSHN---FISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLR 193
Query: 221 LRNNPIKRILVHAFSGLNDVGQIEL 245
+ NN ++ + F L+ + ++L
Sbjct: 194 INNNRLRTLAPGTFDALSALSHLQL 218
Score = 34.3 bits (75), Expect = 0.90
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
+ +SL N I + AF+ + V + L +RT+EP A A L + L+L+ +
Sbjct: 93 VTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFIS 152
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI 321
S L + L + + LG + + L + +L I NN++
Sbjct: 153 SFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRL 199
>M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein.
Length = 394
Score = 64.1 bits (149), Expect = 1e-09
Identities = 59/229 (25%), Positives = 102/229 (44%), Gaps = 12/229 (5%)
Query: 109 LRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRL 168
L+ VP +SP T L L D+ LR D F L+ L L L +++I AF L +
Sbjct: 107 LKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRNV 166
Query: 169 RELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKR 228
++LYI L + ++L + + NRI ++ F+G +N I + NP++
Sbjct: 167 QKLYISKNHLVEIPPNLPSSL---VELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLEN 223
Query: 229 --ILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIR 286
AF GL + + + T P+ E + L L + ++ + +
Sbjct: 224 SGFEPGAFDGLK-LNYLRISEAKLTGIPKDLP--ETLNELHLDHNKIQAIELEDLLRYSK 280
Query: 287 VGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKI----DGIEELSLVQ 331
+ RL L + + +I+ GS L + L + NNK+ G+ +L L+Q
Sbjct: 281 LYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQ 329
Score = 44.0 bits (99), Expect = 0.001
Identities = 22/77 (28%), Positives = 40/77 (51%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L+ +D+ ++ F GLQH+ L + NNKI I E + +V+ ++ NH++E P
Sbjct: 121 LDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRNVQKLYISKNHLVEIP 180
Query: 350 EAVVLEVENIIIRGNHL 366
+ + + I N +
Sbjct: 181 PNLPSSLVELRIHDNRI 197
>AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 232
Score = 63.7 bits (148), Expect = 1e-09
Identities = 65/225 (28%), Positives = 101/225 (44%), Gaps = 9/225 (4%)
Query: 129 DLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAA 188
+L L+ F HLR L L L +L+ I AF GL L+ L +Q+ L + + A
Sbjct: 3 NLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWE 62
Query: 189 LQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-S 247
L ++ S+ L N I+ + +F G + + + L +N + I V A + L + + L +
Sbjct: 63 LPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALN 122
Query: 248 GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG 307
I I AF L + VL+L + L P L R+ LSL G + + F
Sbjct: 123 RISHIPDYAFQNLTSLVVLDLNYNKLQE-FPVAIRTLGRLQELSLN----GAMDIQEFPD 177
Query: 308 LQHVDTLEICNNKIDGIEEL---SLVQNNSVRVFKLTGNHMLESP 349
L+ +LEI GI L Q +RV +L+ N + E P
Sbjct: 178 LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP 222
Score = 50.4 bits (115), Expect = 1e-05
Identities = 42/155 (27%), Positives = 72/155 (46%), Gaps = 5/155 (3%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYI 173
SGL S+ L L L + ++A L L+ L LDA ++ + +F GL LR L++
Sbjct: 37 SGLY-SLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWL 95
Query: 174 QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHA 233
L + A L + ++ L NRI+ I YAF + ++ L N ++ V
Sbjct: 96 DDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDLNYNKLQEFPV-- 153
Query: 234 FSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
+ +G+++ S ++ Q F L+G LE+
Sbjct: 154 --AIRTLGRLQELSLNGAMDIQEFPDLKGTTSLEI 186
Score = 44.4 bits (100), Expect = 8e-04
Identities = 40/155 (25%), Positives = 71/155 (45%), Gaps = 3/155 (1%)
Query: 200 NRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFA 258
N + +++ F F+ + L N + I AFSGL + + L + + I +A
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 61
Query: 259 GLEGIGVLELAFMDLPSLLPD-TFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEIC 317
L + L L +L SL+P+ +F GL + L L ++ L I V + + L + + +
Sbjct: 62 ELPSLQSLRLD-ANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLA 120
Query: 318 NNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV 352
N+I I + + S+ V L N + E P A+
Sbjct: 121 LNRISHIPDYAFQNLTSLVVLDLNYNKLQEFPVAI 155
>BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 3 protein.
Length = 628
Score = 62.9 bits (146), Expect = 2e-09
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 2/134 (1%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
LSLSR +R + + AFA LR LR L LD LT + RGL LR L + + LA +
Sbjct: 88 LSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALA 147
Query: 183 SFAF-AALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVG 241
+ A + + + L++N + Q+ A +N + L +N + + AFS L+ +
Sbjct: 148 AGALDDCAETLEDLDLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVPAGAFSRLHKLA 207
Query: 242 QIELPSG-IRTIEP 254
++++ S + TI P
Sbjct: 208 RLDMTSNRLTTIPP 221
Score = 32.7 bits (71), Expect = 2.8
Identities = 25/102 (24%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG- 307
IR + AFA L + L L L SL GL+ + L L + L + G+ D
Sbjct: 95 IRHVAAGAFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALAAGALDDC 154
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
+ ++ L++ N ++ + +L + +V L N + P
Sbjct: 155 AETLEDLDLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVP 196
>AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ23915 fis, clone CAS06160. ).
Length = 628
Score = 62.9 bits (146), Expect = 2e-09
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 2/134 (1%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
LSLSR +R + + AFA LR LR L LD LT + RGL LR L + + LA +
Sbjct: 88 LSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALA 147
Query: 183 SFAF-AALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVG 241
+ A + + + L++N + Q+ A +N + L +N + + AFS L+ +
Sbjct: 148 AGALDDCAETLEDLDLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVPAGAFSRLHKLA 207
Query: 242 QIELPSG-IRTIEP 254
++++ S + TI P
Sbjct: 208 RLDMTSNRLTTIPP 221
Score = 32.7 bits (71), Expect = 2.8
Identities = 25/102 (24%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG- 307
IR + AFA L + L L L SL GL+ + L L + L + G+ D
Sbjct: 95 IRHVAAGAFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALAAGALDDC 154
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
+ ++ L++ N ++ + +L + +V L N + P
Sbjct: 155 AETLEDLDLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVP 196
>BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 62.5 bits (145), Expect = 3e-09
Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 1/140 (0%)
Query: 130 LRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAAL 189
LR L D F L +L+ L L C L+ + FRGL L+ LY+Q L + FA L
Sbjct: 119 LRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADL 178
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSG 248
N++ + L NR+ + + F G ++ + L N ++ + AF GL+ + + L +
Sbjct: 179 ANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNS 238
Query: 249 IRTIEPQAFAGLEGIGVLEL 268
+ ++ +A A L + L L
Sbjct: 239 LASLPGEALADLPSLEFLRL 258
Score = 56.0 bits (129), Expect = 3e-07
Identities = 56/224 (25%), Positives = 93/224 (41%), Gaps = 4/224 (1%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S V C + VP L PS +L L +R LR F L L L + NL+ I
Sbjct: 40 SPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLIRTLRPGTFG--SNLLTLWLFSNNLSTI 97
Query: 158 RPFAFRGLPRLRELYI-QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFI 216
P FR L L EL + + L +++ F L+ + S+ L +++ + F G +
Sbjct: 98 YPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSL 157
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPS 275
+ L+ N + + F+ L ++ + L +R + F GL + L L L
Sbjct: 158 QYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQG 217
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNN 319
+ F GL R+ L L + L + + L ++ L + N
Sbjct: 218 VHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 51.2 bits (117), Expect = 7e-06
Identities = 53/242 (21%), Positives = 101/242 (41%), Gaps = 7/242 (2%)
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
P + L++Q+ + T+ F + N+ ++ L N ++ I F + + L +N
Sbjct: 60 PSTQRLFLQNNLIRTLRPGTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNR 117
Query: 226 IKRILV-HAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHG 283
R L F GL + + L + ++ F GL + L L L L D F
Sbjct: 118 HLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFAD 177
Query: 284 LIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
L + L L + L ++ F GL +D L + N++ G+ + + + + L N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNN 237
Query: 344 HMLESP-EAV--VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKVRGR 400
+ P EA+ + +E + + N C+C P ++ + + C +P + +GR
Sbjct: 238 SLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAWFQRARVSSSDVTCATPPERQGR 297
Query: 401 SL 402
L
Sbjct: 298 DL 299
Score = 47.6 bits (108), Expect = 9e-05
Identities = 38/123 (30%), Positives = 52/123 (42%), Gaps = 2/123 (1%)
Query: 104 CNSAALRG-VPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAF 162
C ++L G + GL S+ L L L L+ D FA L L L L L + F
Sbjct: 141 CQLSSLPGNIFRGLV-SLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVF 199
Query: 163 RGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
RGL L L + L V AF L +T + L +N +A + A A + + L
Sbjct: 200 RGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLN 259
Query: 223 NNP 225
NP
Sbjct: 260 ANP 262
Score = 47.2 bits (107), Expect = 1e-04
Identities = 55/213 (25%), Positives = 91/213 (42%), Gaps = 10/213 (4%)
Query: 141 LRQLRRLALDACNLTRIR--PFAFRGLPRLRELYIQH-TPLATVDSFAFAALQ---NITS 194
LR+L + AC L + P A P L Y T ++F+ L +
Sbjct: 5 LRRLLQAPASACLLLMLLALPLAAPSCPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQR 64
Query: 195 IVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG--IRTI 252
+ L +N I + F G+N + L NN + I F L + +++L +R++
Sbjct: 65 LFLQNNLIRTLRPGTF-GSNLLTLWLFSNN-LSTIYPGTFRHLQALEELDLGDNRHLRSL 122
Query: 253 EPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVD 312
EP F GLE + L L L SL + F GL+ + L L+E+ L ++ F L ++
Sbjct: 123 EPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLS 182
Query: 313 TLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
L + N++ + E S+ L GN +
Sbjct: 183 HLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRL 215
>BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 62.5 bits (145), Expect = 3e-09
Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 1/140 (0%)
Query: 130 LRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAAL 189
LR L D F L +L+ L L C L+ + FRGL L+ LY+Q L + FA L
Sbjct: 119 LRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADL 178
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSG 248
N++ + L NR+ + + F G ++ + L N ++ + AF GL+ + + L +
Sbjct: 179 ANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNS 238
Query: 249 IRTIEPQAFAGLEGIGVLEL 268
+ ++ +A A L + L L
Sbjct: 239 LASLPGEALADLPSLEFLRL 258
Score = 56.0 bits (129), Expect = 3e-07
Identities = 56/224 (25%), Positives = 93/224 (41%), Gaps = 4/224 (1%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S V C + VP L PS +L L +R LR F L L L + NL+ I
Sbjct: 40 SPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLIRTLRPGTFG--SNLLTLWLFSNNLSTI 97
Query: 158 RPFAFRGLPRLRELYI-QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFI 216
P FR L L EL + + L +++ F L+ + S+ L +++ + F G +
Sbjct: 98 YPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSL 157
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPS 275
+ L+ N + + F+ L ++ + L +R + F GL + L L L
Sbjct: 158 QYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQG 217
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNN 319
+ F GL R+ L L + L + + L ++ L + N
Sbjct: 218 VHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 51.2 bits (117), Expect = 7e-06
Identities = 53/242 (21%), Positives = 101/242 (41%), Gaps = 7/242 (2%)
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
P + L++Q+ + T+ F + N+ ++ L N ++ I F + + L +N
Sbjct: 60 PSTQRLFLQNNLIRTLRPGTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNR 117
Query: 226 IKRILV-HAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHG 283
R L F GL + + L + ++ F GL + L L L L D F
Sbjct: 118 HLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFAD 177
Query: 284 LIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
L + L L + L ++ F GL +D L + N++ G+ + + + + L N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNN 237
Query: 344 HMLESP-EAV--VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKVRGR 400
+ P EA+ + +E + + N C+C P ++ + + C +P + +GR
Sbjct: 238 SLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAWFQRARVSSSDVTCATPPERQGR 297
Query: 401 SL 402
L
Sbjct: 298 DL 299
Score = 47.6 bits (108), Expect = 9e-05
Identities = 38/123 (30%), Positives = 52/123 (42%), Gaps = 2/123 (1%)
Query: 104 CNSAALRG-VPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAF 162
C ++L G + GL S+ L L L L+ D FA L L L L L + F
Sbjct: 141 CQLSSLPGNIFRGLV-SLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVF 199
Query: 163 RGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
RGL L L + L V AF L +T + L +N +A + A A + + L
Sbjct: 200 RGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLN 259
Query: 223 NNP 225
NP
Sbjct: 260 ANP 262
Score = 47.2 bits (107), Expect = 1e-04
Identities = 55/213 (25%), Positives = 91/213 (42%), Gaps = 10/213 (4%)
Query: 141 LRQLRRLALDACNLTRIR--PFAFRGLPRLRELYIQH-TPLATVDSFAFAALQ---NITS 194
LR+L + AC L + P A P L Y T ++F+ L +
Sbjct: 5 LRRLLQAPASACLLLMLLALPLAAPSCPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQR 64
Query: 195 IVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG--IRTI 252
+ L +N I + F G+N + L NN + I F L + +++L +R++
Sbjct: 65 LFLQNNLIRTLRPGTF-GSNLLTLWLFSNN-LSTIYPGTFRHLQALEELDLGDNRHLRSL 122
Query: 253 EPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVD 312
EP F GLE + L L L SL + F GL+ + L L+E+ L ++ F L ++
Sbjct: 123 EPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLS 182
Query: 313 TLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
L + N++ + E S+ L GN +
Sbjct: 183 HLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRL 215
>AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3
protein.
Length = 420
Score = 62.5 bits (145), Expect = 3e-09
Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 1/140 (0%)
Query: 130 LRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAAL 189
LR L D F L +L+ L L C L+ + FRGL L+ LY+Q L + FA L
Sbjct: 119 LRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADL 178
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSG 248
N++ + L NR+ + + F G ++ + L N ++ + AF GL+ + + L +
Sbjct: 179 ANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNS 238
Query: 249 IRTIEPQAFAGLEGIGVLEL 268
+ ++ +A A L + L L
Sbjct: 239 LASLPGEALADLPSLEFLRL 258
Score = 56.4 bits (130), Expect = 2e-07
Identities = 56/224 (25%), Positives = 93/224 (41%), Gaps = 4/224 (1%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S V C + VP L PS +L L +R LR F L L L + NL+ I
Sbjct: 40 SPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLIRTLRPSTFG--SNLLTLWLFSNNLSTI 97
Query: 158 RPFAFRGLPRLRELYI-QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFI 216
P FR L L EL + + L +++ F L+ + S+ L +++ + F G +
Sbjct: 98 YPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSL 157
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPS 275
+ L+ N + + F+ L ++ + L +R + F GL + L L L
Sbjct: 158 QYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQG 217
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNN 319
+ F GL R+ L L + L + + L ++ L + N
Sbjct: 218 VHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 51.6 bits (118), Expect = 6e-06
Identities = 53/242 (21%), Positives = 101/242 (41%), Gaps = 7/242 (2%)
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
P + L++Q+ + T+ F + N+ ++ L N ++ I F + + L +N
Sbjct: 60 PSTQRLFLQNNLIRTLRPSTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNR 117
Query: 226 IKRILV-HAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHG 283
R L F GL + + L + ++ F GL + L L L L D F
Sbjct: 118 HLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFAD 177
Query: 284 LIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
L + L L + L ++ F GL +D L + N++ G+ + + + + L N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNN 237
Query: 344 HMLESP-EAV--VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKVRGR 400
+ P EA+ + +E + + N C+C P ++ + + C +P + +GR
Sbjct: 238 SLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAWFQRARVSSSDVTCATPPERQGR 297
Query: 401 SL 402
L
Sbjct: 298 DL 299
Score = 47.6 bits (108), Expect = 9e-05
Identities = 55/213 (25%), Positives = 91/213 (42%), Gaps = 10/213 (4%)
Query: 141 LRQLRRLALDACNLTRIR--PFAFRGLPRLRELYIQH-TPLATVDSFAFAALQ---NITS 194
LR+L + AC L + P A P L Y T ++F+ L +
Sbjct: 5 LRRLLQAPASACLLLMLLALPLAAPSCPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQR 64
Query: 195 IVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG--IRTI 252
+ L +N I + F G+N + L NN + I F L + +++L +R++
Sbjct: 65 LFLQNNLIRTLRPSTF-GSNLLTLWLFSNN-LSTIYPGTFRHLQALEELDLGDNRHLRSL 122
Query: 253 EPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVD 312
EP F GLE + L L L SL + F GL+ + L L+E+ L ++ F L ++
Sbjct: 123 EPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLS 182
Query: 313 TLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
L + N++ + E S+ L GN +
Sbjct: 183 HLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRL 215
Score = 47.6 bits (108), Expect = 9e-05
Identities = 38/123 (30%), Positives = 52/123 (42%), Gaps = 2/123 (1%)
Query: 104 CNSAALRG-VPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAF 162
C ++L G + GL S+ L L L L+ D FA L L L L L + F
Sbjct: 141 CQLSSLPGNIFRGLV-SLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVF 199
Query: 163 RGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
RGL L L + L V AF L +T + L +N +A + A A + + L
Sbjct: 200 RGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLN 259
Query: 223 NNP 225
NP
Sbjct: 260 ANP 262
>AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolog-1
protein.
Length = 420
Score = 62.5 bits (145), Expect = 3e-09
Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 1/140 (0%)
Query: 130 LRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAAL 189
LR L D F L +L+ L L C L+ + FRGL L+ LY+Q L + FA L
Sbjct: 119 LRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADL 178
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSG 248
N++ + L NR+ + + F G ++ + L N ++ + AF GL+ + + L +
Sbjct: 179 ANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNS 238
Query: 249 IRTIEPQAFAGLEGIGVLEL 268
+ ++ +A A L + L L
Sbjct: 239 LASLPGEALADLPSLEFLRL 258
Score = 56.0 bits (129), Expect = 3e-07
Identities = 56/224 (25%), Positives = 93/224 (41%), Gaps = 4/224 (1%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S V C + VP L PS +L L +R LR F L L L + NL+ I
Sbjct: 40 SPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLIRTLRPGTFG--SNLLTLWLFSNNLSTI 97
Query: 158 RPFAFRGLPRLRELYI-QHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFI 216
P FR L L EL + + L +++ F L+ + S+ L +++ + F G +
Sbjct: 98 YPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSL 157
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPS 275
+ L+ N + + F+ L ++ + L +R + F GL + L L L
Sbjct: 158 QYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQG 217
Query: 276 LLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNN 319
+ F GL R+ L L + L + + L ++ L + N
Sbjct: 218 VHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 51.2 bits (117), Expect = 7e-06
Identities = 53/242 (21%), Positives = 101/242 (41%), Gaps = 7/242 (2%)
Query: 166 PRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
P + L++Q+ + T+ F + N+ ++ L N ++ I F + + L +N
Sbjct: 60 PSTQRLFLQNNLIRTLRPGTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNR 117
Query: 226 IKRILV-HAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHG 283
R L F GL + + L + ++ F GL + L L L L D F
Sbjct: 118 HLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFAD 177
Query: 284 LIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
L + L L + L ++ F GL +D L + N++ G+ + + + + L N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNN 237
Query: 344 HMLESP-EAV--VLEVENIIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKVRGR 400
+ P EA+ + +E + + N C+C P ++ + + C +P + +GR
Sbjct: 238 SLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAWFQRARVSSSDVTCATPPERQGR 297
Query: 401 SL 402
L
Sbjct: 298 DL 299
Score = 47.6 bits (108), Expect = 9e-05
Identities = 38/123 (30%), Positives = 52/123 (42%), Gaps = 2/123 (1%)
Query: 104 CNSAALRG-VPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAF 162
C ++L G + GL S+ L L L L+ D FA L L L L L + F
Sbjct: 141 CQLSSLPGNIFRGLV-SLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVF 199
Query: 163 RGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLR 222
RGL L L + L V AF L +T + L +N +A + A A + + L
Sbjct: 200 RGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLN 259
Query: 223 NNP 225
NP
Sbjct: 260 ANP 262
Score = 47.2 bits (107), Expect = 1e-04
Identities = 55/213 (25%), Positives = 91/213 (42%), Gaps = 10/213 (4%)
Query: 141 LRQLRRLALDACNLTRIR--PFAFRGLPRLRELYIQH-TPLATVDSFAFAALQ---NITS 194
LR+L + AC L + P A P L Y T ++F+ L +
Sbjct: 5 LRRLLQAPASACLLLMLLALPLAAPSCPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQR 64
Query: 195 IVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG--IRTI 252
+ L +N I + F G+N + L NN + I F L + +++L +R++
Sbjct: 65 LFLQNNLIRTLRPGTF-GSNLLTLWLFSNN-LSTIYPGTFRHLQALEELDLGDNRHLRSL 122
Query: 253 EPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVD 312
EP F GLE + L L L SL + F GL+ + L L+E+ L ++ F L ++
Sbjct: 123 EPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLS 182
Query: 313 TLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
L + N++ + E S+ L GN +
Sbjct: 183 HLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRL 215
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 61.7 bits (143), Expect = 5e-09
Identities = 42/167 (25%), Positives = 86/167 (51%), Gaps = 12/167 (7%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLP 274
+ I+L N + R++ FSGL + + L S GI TI + F+ L+ + VL++++ +
Sbjct: 59 VERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKVR 118
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
L DTF+GL + RL + +++ I F GL + + + N++ + + V +
Sbjct: 119 KLQKDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLSY 178
Query: 335 VRVFK--------LTGNHMLESPEAVVL---EVENIIIRGNHLPCEC 370
+++FK L+ N + P+ +V +++++ + GN C+C
Sbjct: 179 LQIFKISFIKFLYLSDNFLTSLPQEMVSYMPDLDSLYLHGNPWTCDC 225
Score = 60.5 bits (140), Expect = 1e-08
Identities = 36/143 (25%), Positives = 64/143 (44%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C ++V C L +P + P+V +++L L L F+ L +L L L + +
Sbjct: 35 CYMPTEVHCTFRYLTSIPDSIPPNVERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIH 94
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
I F L L+ L + + + + F L+++T + + HN I I F G NF
Sbjct: 95 TIPDKTFSDLQALQVLKMSYNKVRKLQKDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNF 154
Query: 216 INLISLRNNPIKRILVHAFSGLN 238
+ L+ L N + ++ F L+
Sbjct: 155 LRLVHLEGNQLTKLHPDTFVSLS 177
Score = 50.0 bits (114), Expect = 2e-05
Identities = 28/129 (21%), Positives = 62/129 (48%), Gaps = 1/129 (0%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
+ R+ L +L R+ F GL +L L + + T+ F+ LQ + + +++N++
Sbjct: 59 VERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKVR 118
Query: 204 QIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEG 262
+++ F G + + + +N I+ I F GLN + + L + + P F L
Sbjct: 119 KLQKDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLSY 178
Query: 263 IGVLELAFM 271
+ + +++F+
Sbjct: 179 LQIFKISFI 187
>Z24680-1|CAA80847.1| 662|Homo sapiens garp protein.
Length = 662
Score = 61.3 bits (142), Expect = 7e-09
Identities = 48/174 (27%), Positives = 77/174 (44%), Gaps = 5/174 (2%)
Query: 101 QVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPF 160
+V C L VPS L P L LS LR + + LR L L ++ ++P
Sbjct: 32 KVSCQVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPG 91
Query: 161 AFRGLPRLRELYIQHTPLATVDSFA---FAALQNITSIVLTHNRI-AQIESYAFAGTNFI 216
AF+ L L L + H LA + + L +TS+ L+ N + + + +
Sbjct: 92 AFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSL 151
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSGI-RTIEPQAFAGLEGIGVLELA 269
+ +SL N + R+ H F + + Q++L S + IE AF GL + L L+
Sbjct: 152 HTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLS 205
Score = 42.7 bits (96), Expect = 0.003
Identities = 70/284 (24%), Positives = 120/284 (42%), Gaps = 34/284 (11%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
G +PS+ LSL+ L L F + L +L L + L I AF GLPRL L +
Sbjct: 146 GEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLS 205
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF-INLISLRNNPI------- 226
L + F +LQ + + L+ N I ++ + F + + LR N +
Sbjct: 206 RNSLTCISDF---SLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLA 262
Query: 227 ---KRILVHAFSGL--------NDVGQIELPS-GIRTIEPQAFAG-LEGIGVLELAFMDL 273
+ I ++ + L D I PS G + A +G G + +L +DL
Sbjct: 263 ALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWSALPLSAPSGNASGRPLSQLLNLDL 322
Query: 274 P----SLLPDTF-HGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELS 328
L+PD+F L + L+L + L + L + L++ +N ++ + EL
Sbjct: 323 SYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETL-ELG 381
Query: 329 LVQNNSVRVFKLTGNHMLESPE---AVVLEVENIIIRGNHL-PC 368
S+R L GN + + P A + ++ + ++GN + PC
Sbjct: 382 ARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPC 425
Score = 38.7 bits (86), Expect = 0.042
Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 22/176 (12%)
Query: 168 LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIK 227
LR L + ++ + AF AL ++ + L HNR+A + + G P+
Sbjct: 75 LRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLG----------PLP 124
Query: 228 RILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV 287
R+ SG + L SG+ +E + + L LA L L TF + +
Sbjct: 125 RVTSLDLSGNS------LYSGL--LE-RLLGEAPSLHTLSLAENSLTRLTRHTFRDMPAL 175
Query: 288 GRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
+L L + L I+ G+F+GL + L + N + I + SL Q +RV L+ N
Sbjct: 176 EQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQ---LRVLDLSCN 228
>BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein.
Length = 662
Score = 61.3 bits (142), Expect = 7e-09
Identities = 48/174 (27%), Positives = 77/174 (44%), Gaps = 5/174 (2%)
Query: 101 QVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPF 160
+V C L VPS L P L LS LR + + LR L L ++ ++P
Sbjct: 32 KVSCQVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPG 91
Query: 161 AFRGLPRLRELYIQHTPLATVDSFA---FAALQNITSIVLTHNRI-AQIESYAFAGTNFI 216
AF+ L L L + H LA + + L +TS+ L+ N + + + +
Sbjct: 92 AFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSL 151
Query: 217 NLISLRNNPIKRILVHAFSGLNDVGQIELPSGI-RTIEPQAFAGLEGIGVLELA 269
+ +SL N + R+ H F + + Q++L S + IE AF GL + L L+
Sbjct: 152 HTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLS 205
Score = 42.7 bits (96), Expect = 0.003
Identities = 70/284 (24%), Positives = 120/284 (42%), Gaps = 34/284 (11%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
G +PS+ LSL+ L L F + L +L L + L I AF GLPRL L +
Sbjct: 146 GEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLS 205
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF-INLISLRNNPI------- 226
L + F +LQ + + L+ N I ++ + F + + LR N +
Sbjct: 206 RNSLTCISDF---SLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLA 262
Query: 227 ---KRILVHAFSGL--------NDVGQIELPS-GIRTIEPQAFAG-LEGIGVLELAFMDL 273
+ I ++ + L D I PS G + A +G G + +L +DL
Sbjct: 263 ALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWSALPLSAPSGNASGRPLSQLLNLDL 322
Query: 274 P----SLLPDTF-HGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELS 328
L+PD+F L + L+L + L + L + L++ +N ++ + EL
Sbjct: 323 SYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETL-ELG 381
Query: 329 LVQNNSVRVFKLTGNHMLESPE---AVVLEVENIIIRGNHL-PC 368
S+R L GN + + P A + ++ + ++GN + PC
Sbjct: 382 ARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPC 425
Score = 38.7 bits (86), Expect = 0.042
Identities = 46/176 (26%), Positives = 76/176 (43%), Gaps = 22/176 (12%)
Query: 168 LRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIK 227
LR L + ++ + AF AL ++ + L HNR+A + + G P+
Sbjct: 75 LRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLG----------PLP 124
Query: 228 RILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV 287
R+ SG + L SG+ +E + + L LA L L TF + +
Sbjct: 125 RVTSLDLSGNS------LYSGL--LE-RLLGEAPSLHTLSLAENSLTRLTRHTFRDMPAL 175
Query: 288 GRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
+L L + L I+ G+F+GL + L + N + I + SL Q +RV L+ N
Sbjct: 176 EQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQ---LRVLDLSCN 228
>AY358116-1|AAQ88483.1| 548|Homo sapiens LGI3 protein.
Length = 548
Score = 61.3 bits (142), Expect = 7e-09
Identities = 34/117 (29%), Positives = 59/117 (50%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+ VP L V L+L A ++ AF+HL L+ L L++ T I AF GL L+
Sbjct: 56 KAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQ 115
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
L+I++ + + F F L+++T + L +N + + F + +N + LR N +
Sbjct: 116 YLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSL 172
Score = 39.9 bits (89), Expect = 0.018
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + +I +F GL H+ L I NN I + + + S+ L N++ P
Sbjct: 93 LLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLP 152
Query: 350 EAVV--LEVEN-IIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
+ L++ N + +RGN L C+C LA + YC SP
Sbjct: 153 RDIFRPLDILNDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASP 200
Score = 37.9 bits (84), Expect = 0.073
Identities = 23/99 (23%), Positives = 44/99 (44%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L L + I+ AF LP L+ L + + AF L ++ + + +N I +
Sbjct: 69 LTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALS 128
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ F G + +SL NN ++ + F L+ + ++L
Sbjct: 129 KFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDL 167
Score = 37.5 bits (83), Expect = 0.097
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Query: 192 ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IR 250
+ S+ L + ++I+ AF+ + + L +N I +AF+GL+ + + + + I
Sbjct: 66 VISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIW 125
Query: 251 TIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
+ F GL+ + L LA +L +L D F L + L LR + L
Sbjct: 126 ALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSL 172
>AJ487961-1|CAD32308.1| 548|Homo sapiens LGI1-like protein 4
protein.
Length = 548
Score = 61.3 bits (142), Expect = 7e-09
Identities = 34/117 (29%), Positives = 59/117 (50%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+ VP L V L+L A ++ AF+HL L+ L L++ T I AF GL L+
Sbjct: 56 KAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQ 115
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
L+I++ + + F F L+++T + L +N + + F + +N + LR N +
Sbjct: 116 YLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSL 172
Score = 39.9 bits (89), Expect = 0.018
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + +I +F GL H+ L I NN I + + + S+ L N++ P
Sbjct: 93 LLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLP 152
Query: 350 EAVV--LEVEN-IIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
+ L++ N + +RGN L C+C LA + YC SP
Sbjct: 153 RDIFRPLDILNDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASP 200
Score = 37.9 bits (84), Expect = 0.073
Identities = 23/99 (23%), Positives = 44/99 (44%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L L + I+ AF LP L+ L + + AF L ++ + + +N I +
Sbjct: 69 LTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALS 128
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ F G + +SL NN ++ + F L+ + ++L
Sbjct: 129 KFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDL 167
Score = 37.5 bits (83), Expect = 0.097
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Query: 192 ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IR 250
+ S+ L + ++I+ AF+ + + L +N I +AF+GL+ + + + + I
Sbjct: 66 VISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIW 125
Query: 251 TIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
+ F GL+ + L LA +L +L D F L + L LR + L
Sbjct: 126 ALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSL 172
>AJ487518-1|CAD31786.1| 548|Homo sapiens leucine-rich glioma
inactivated protein 3 protein.
Length = 548
Score = 61.3 bits (142), Expect = 7e-09
Identities = 34/117 (29%), Positives = 59/117 (50%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+ VP L V L+L A ++ AF+HL L+ L L++ T I AF GL L+
Sbjct: 56 KAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQ 115
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
L+I++ + + F F L+++T + L +N + + F + +N + LR N +
Sbjct: 116 YLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSL 172
Score = 39.9 bits (89), Expect = 0.018
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + +I +F GL H+ L I NN I + + + S+ L N++ P
Sbjct: 93 LLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLP 152
Query: 350 EAVV--LEVEN-IIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
+ L++ N + +RGN L C+C LA + YC SP
Sbjct: 153 RDIFRPLDILNDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASP 200
Score = 37.9 bits (84), Expect = 0.073
Identities = 23/99 (23%), Positives = 44/99 (44%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L L + I+ AF LP L+ L + + AF L ++ + + +N I +
Sbjct: 69 LTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALS 128
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ F G + +SL NN ++ + F L+ + ++L
Sbjct: 129 KFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDL 167
Score = 37.5 bits (83), Expect = 0.097
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Query: 192 ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IR 250
+ S+ L + ++I+ AF+ + + L +N I +AF+GL+ + + + + I
Sbjct: 66 VISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIW 125
Query: 251 TIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
+ F GL+ + L LA +L +L D F L + L LR + L
Sbjct: 126 ALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSL 172
>AF467956-1|AAM49554.1| 548|Homo sapiens LGI3 protein.
Length = 548
Score = 61.3 bits (142), Expect = 7e-09
Identities = 34/117 (29%), Positives = 59/117 (50%)
Query: 110 RGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLR 169
+ VP L V L+L A ++ AF+HL L+ L L++ T I AF GL L+
Sbjct: 56 KAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQ 115
Query: 170 ELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
L+I++ + + F F L+++T + L +N + + F + +N + LR N +
Sbjct: 116 YLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSL 172
Score = 39.9 bits (89), Expect = 0.018
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + +I +F GL H+ L I NN I + + + S+ L N++ P
Sbjct: 93 LLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLP 152
Query: 350 EAVV--LEVEN-IIIRGNHLPCECGRDPFTNPLALSQDFAEENYCISP 394
+ L++ N + +RGN L C+C LA + YC SP
Sbjct: 153 RDIFRPLDILNDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASP 200
Score = 37.9 bits (84), Expect = 0.073
Identities = 23/99 (23%), Positives = 44/99 (44%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L L + I+ AF LP L+ L + + AF L ++ + + +N I +
Sbjct: 69 LTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALS 128
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ F G + +SL NN ++ + F L+ + ++L
Sbjct: 129 KFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDL 167
Score = 37.5 bits (83), Expect = 0.097
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Query: 192 ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IR 250
+ S+ L + ++I+ AF+ + + L +N I +AF+GL+ + + + + I
Sbjct: 66 VISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIW 125
Query: 251 TIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
+ F GL+ + L LA +L +L D F L + L LR + L
Sbjct: 126 ALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSL 172
>BC087848-1|AAH87848.1| 261|Homo sapiens LGI4 protein protein.
Length = 261
Score = 60.9 bits (141), Expect = 9e-09
Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S+ +C + +P SP++ LSL R + L++ +F + L L + + + I
Sbjct: 34 SKDSALCEGSP--DLPVSFSPTLLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVI 91
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF GL L+ L+I+ + ++ A L+++T + L +N + + + F G + +
Sbjct: 92 EDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLT 151
Query: 218 LISLRNNPIK 227
+ LR NP +
Sbjct: 152 HVDLRGNPFQ 161
Score = 44.8 bits (101), Expect = 6e-04
Identities = 25/102 (24%), Positives = 48/102 (47%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
L L+L +T+++ +F +P L L + ++ AFA L ++ + + N I
Sbjct: 54 LLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIG 113
Query: 204 QIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
I A G + +SL NN ++ + F GL+ + ++L
Sbjct: 114 SISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDL 155
Score = 36.3 bits (80), Expect = 0.22
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L + +I+ +F GL H+ L I +N+I I + +L S+ L NH+ P
Sbjct: 81 LLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLP 140
Query: 350 EAVVLEVE---NIIIRGNHLPCEC 370
+ ++ ++ +RGN C+C
Sbjct: 141 RFLFRGLDTLTHVDLRGNPFQCDC 164
Score = 31.1 bits (67), Expect = 8.4
Identities = 18/97 (18%), Positives = 43/97 (44%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+G+ ++ +F + + +L + D F GL + L + ++++G I +
Sbjct: 62 TGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALR 121
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
GL+ + L + NN ++ + +++ L GN
Sbjct: 122 GLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDLRGN 158
>AY358121-1|AAQ88488.1| 261|Homo sapiens LGI4 protein.
Length = 261
Score = 60.9 bits (141), Expect = 9e-09
Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S+ +C + +P SP++ LSL R + L++ +F + L L + + + I
Sbjct: 34 SKDSALCEGSP--DLPVSFSPTLLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVI 91
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF GL L+ L+I+ + ++ A L+++T + L +N + + + F G + +
Sbjct: 92 EDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLT 151
Query: 218 LISLRNNPIK 227
+ LR NP +
Sbjct: 152 HVDLRGNPFQ 161
Score = 44.8 bits (101), Expect = 6e-04
Identities = 25/102 (24%), Positives = 48/102 (47%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
L L+L +T+++ +F +P L L + ++ AFA L ++ + + N I
Sbjct: 54 LLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIG 113
Query: 204 QIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
I A G + +SL NN ++ + F GL+ + ++L
Sbjct: 114 SISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDL 155
Score = 36.3 bits (80), Expect = 0.22
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L + +I+ +F GL H+ L I +N+I I + +L S+ L NH+ P
Sbjct: 81 LLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLP 140
Query: 350 EAVVLEVE---NIIIRGNHLPCEC 370
+ ++ ++ +RGN C+C
Sbjct: 141 RFLFRGLDTLTHVDLRGNPFQCDC 164
Score = 31.1 bits (67), Expect = 8.4
Identities = 18/97 (18%), Positives = 43/97 (44%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+G+ ++ +F + + +L + D F GL + L + ++++G I +
Sbjct: 62 TGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALR 121
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
GL+ + L + NN ++ + +++ L GN
Sbjct: 122 GLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDLRGN 158
>AJ487959-1|CAD32306.1| 537|Homo sapiens LGI1-like protein 3
protein.
Length = 537
Score = 60.9 bits (141), Expect = 9e-09
Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S+ +C + +P SP++ LSL R + L++ +F + L L + + + I
Sbjct: 34 SKDSALCEGSP--DLPVSFSPTLLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVI 91
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF GL L+ L+I+ + ++ A L+++T + L +N + + + F G + +
Sbjct: 92 EDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLT 151
Query: 218 LISLRNNPIK 227
+ LR NP +
Sbjct: 152 HVDLRGNPFQ 161
Score = 44.8 bits (101), Expect = 6e-04
Identities = 25/102 (24%), Positives = 48/102 (47%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
L L+L +T+++ +F +P L L + ++ AFA L ++ + + N I
Sbjct: 54 LLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIG 113
Query: 204 QIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
I A G + +SL NN ++ + F GL+ + ++L
Sbjct: 114 SISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDL 155
Score = 36.3 bits (80), Expect = 0.22
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L + +I+ +F GL H+ L I +N+I I + +L S+ L NH+ P
Sbjct: 81 LLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLP 140
Query: 350 EAVVLEVE---NIIIRGNHLPCEC 370
+ ++ ++ +RGN C+C
Sbjct: 141 RFLFRGLDTLTHVDLRGNPFQCDC 164
Score = 31.1 bits (67), Expect = 8.4
Identities = 18/97 (18%), Positives = 43/97 (44%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+G+ ++ +F + + +L + D F GL + L + ++++G I +
Sbjct: 62 TGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALR 121
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
GL+ + L + NN ++ + +++ L GN
Sbjct: 122 GLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDLRGN 158
>AJ487519-1|CAD31787.1| 537|Homo sapiens leucine-rich glioma
inactivated protein 4 protein.
Length = 537
Score = 60.9 bits (141), Expect = 9e-09
Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S+ +C + +P SP++ LSL R + L++ +F + L L + + + I
Sbjct: 34 SKDSALCEGSP--DLPVSFSPTLLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVI 91
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF GL L+ L+I+ + ++ A L+++T + L +N + + + F G + +
Sbjct: 92 EDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLT 151
Query: 218 LISLRNNPIK 227
+ LR NP +
Sbjct: 152 HVDLRGNPFQ 161
Score = 44.8 bits (101), Expect = 6e-04
Identities = 25/102 (24%), Positives = 48/102 (47%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
L L+L +T+++ +F +P L L + ++ AFA L ++ + + N I
Sbjct: 54 LLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIG 113
Query: 204 QIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
I A G + +SL NN ++ + F GL+ + ++L
Sbjct: 114 SISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDL 155
Score = 36.3 bits (80), Expect = 0.22
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L + +I+ +F GL H+ L I +N+I I + +L S+ L NH+ P
Sbjct: 81 LLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLP 140
Query: 350 EAVVLEVE---NIIIRGNHLPCEC 370
+ ++ ++ +RGN C+C
Sbjct: 141 RFLFRGLDTLTHVDLRGNPFQCDC 164
Score = 31.1 bits (67), Expect = 8.4
Identities = 18/97 (18%), Positives = 43/97 (44%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+G+ ++ +F + + +L + D F GL + L + ++++G I +
Sbjct: 62 TGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALR 121
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
GL+ + L + NN ++ + +++ L GN
Sbjct: 122 GLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDLRGN 158
>AF467954-1|AAM49552.1| 537|Homo sapiens LGI4 protein.
Length = 537
Score = 60.9 bits (141), Expect = 9e-09
Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Query: 98 SQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRI 157
S+ +C + +P SP++ LSL R + L++ +F + L L + + + I
Sbjct: 34 SKDSALCEGSP--DLPVSFSPTLLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVI 91
Query: 158 RPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFIN 217
AF GL L+ L+I+ + ++ A L+++T + L +N + + + F G + +
Sbjct: 92 EDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLT 151
Query: 218 LISLRNNPIK 227
+ LR NP +
Sbjct: 152 HVDLRGNPFQ 161
Score = 44.8 bits (101), Expect = 6e-04
Identities = 25/102 (24%), Positives = 48/102 (47%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIA 203
L L+L +T+++ +F +P L L + ++ AFA L ++ + + N I
Sbjct: 54 LLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIG 113
Query: 204 QIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
I A G + +SL NN ++ + F GL+ + ++L
Sbjct: 114 SISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDL 155
Score = 36.3 bits (80), Expect = 0.22
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L + +I+ +F GL H+ L I +N+I I + +L S+ L NH+ P
Sbjct: 81 LLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLP 140
Query: 350 EAVVLEVE---NIIIRGNHLPCEC 370
+ ++ ++ +RGN C+C
Sbjct: 141 RFLFRGLDTLTHVDLRGNPFQCDC 164
Score = 31.1 bits (67), Expect = 8.4
Identities = 18/97 (18%), Positives = 43/97 (44%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+G+ ++ +F + + +L + D F GL + L + ++++G I +
Sbjct: 62 TGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALR 121
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
GL+ + L + NN ++ + +++ L GN
Sbjct: 122 GLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDLRGN 158
>BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein.
Length = 743
Score = 60.5 bits (140), Expect = 1e-08
Identities = 36/140 (25%), Positives = 62/140 (44%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C S+V C +L VP+G++ V +++L ++ L +FA L +L L + +
Sbjct: 33 CYVPSEVHCTFRSLASVPAGIAKHVERINLGFNSIQALSETSFAGLTKLELLMIHGNEIP 92
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
I A R L L+ + L + L N+ + + HN+I I AF G
Sbjct: 93 SIPDGALRDLSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTS 152
Query: 216 INLISLRNNPIKRILVHAFS 235
+ L+ L N + ++ FS
Sbjct: 153 LRLLHLEGNLLHQLHPSTFS 172
Score = 37.1 bits (82), Expect = 0.13
Identities = 35/167 (20%), Positives = 73/167 (43%), Gaps = 12/167 (7%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
+ I+L N I+ + +F+GL + + + I +I A L + V + ++ L
Sbjct: 57 VERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLR 116
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE-------- 326
+ T GL + RL + + + I +F+GL + L + N + +
Sbjct: 117 VITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTF 176
Query: 327 LSLVQNNSVRVFKLTGNHMLESPEAVVLE---VENIIIRGNHLPCEC 370
L + +++R L N + P +++ +EN+ ++GN C+C
Sbjct: 177 LDYFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYLQGNPWTCDC 223
>BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein.
Length = 743
Score = 60.5 bits (140), Expect = 1e-08
Identities = 36/140 (25%), Positives = 62/140 (44%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C S+V C +L VP+G++ V +++L ++ L +FA L +L L + +
Sbjct: 33 CYVPSEVHCTFRSLASVPAGIAKHVERINLGFNSIQALSETSFAGLTKLELLMIHGNEIP 92
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
I A R L L+ + L + L N+ + + HN+I I AF G
Sbjct: 93 SIPDGALRDLSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTS 152
Query: 216 INLISLRNNPIKRILVHAFS 235
+ L+ L N + ++ FS
Sbjct: 153 LRLLHLEGNLLHQLHPSTFS 172
Score = 37.1 bits (82), Expect = 0.13
Identities = 35/167 (20%), Positives = 73/167 (43%), Gaps = 12/167 (7%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
+ I+L N I+ + +F+GL + + + I +I A L + V + ++ L
Sbjct: 57 VERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLR 116
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE-------- 326
+ T GL + RL + + + I +F+GL + L + N + +
Sbjct: 117 VITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTF 176
Query: 327 LSLVQNNSVRVFKLTGNHMLESPEAVVLE---VENIIIRGNHLPCEC 370
L + +++R L N + P +++ +EN+ ++GN C+C
Sbjct: 177 LDYFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYLQGNPWTCDC 223
>BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like family,
member 4 protein.
Length = 837
Score = 60.5 bits (140), Expect = 1e-08
Identities = 36/124 (29%), Positives = 62/124 (50%), Gaps = 2/124 (1%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + V++ D F +L LRRL L+ + R+ P F GL L+ LY+++ + +
Sbjct: 406 LHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEIS 465
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH-AFSGLNDVG 241
+ F ++ N+ + L +N + + Y F+G L +LRNN + V L +
Sbjct: 466 AGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARL-NLRNNKFMYLPVSGVLDQLQSLT 524
Query: 242 QIEL 245
QI+L
Sbjct: 525 QIDL 528
Score = 47.6 bits (108), Expect = 9e-05
Identities = 29/99 (29%), Positives = 46/99 (46%)
Query: 138 FAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVL 197
F L L L + +T I+ F L LR LY+ + + F+ L N+ + L
Sbjct: 397 FTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYL 456
Query: 198 THNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSG 236
+N I +I + F + L+ L NN +K + V+ FSG
Sbjct: 457 EYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG 495
Score = 43.2 bits (97), Expect = 0.002
Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 3/156 (1%)
Query: 169 RELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKR 228
++L++ + VD F + + + L N+I I+ F + + L N I+R
Sbjct: 380 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 439
Query: 229 ILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV 287
+ FSGL+++ + L I+ I F + + +L L L SL F G +
Sbjct: 440 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG-APL 498
Query: 288 GRLSLRESDLGIIKV-GSFDGLQHVDTLEICNNKID 322
RL+LR + + V G D LQ + +++ N D
Sbjct: 499 ARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWD 534
Score = 42.7 bits (96), Expect = 0.003
Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 3/136 (2%)
Query: 186 FAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
F + S+ L +N++ IE AF G + + + L NN +K + F G+ ++ ++
Sbjct: 79 FLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQA 138
Query: 246 PSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIK-VG 303
I+ IE AF L + VL L +L S LPD + L +R + + + +G
Sbjct: 139 DYNLIKYIERGAFNKLHKLKVLILN-DNLISFLPDNIFRFASLTHLDIRGNRIQKLPYIG 197
Query: 304 SFDGLQHVDTLEICNN 319
+ + V L++ +N
Sbjct: 198 VLEHIGRVVELQLEDN 213
Score = 41.5 bits (93), Expect = 0.006
Identities = 48/197 (24%), Positives = 86/197 (43%), Gaps = 9/197 (4%)
Query: 213 TNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFM 271
+NF +L + +NN + + + F + + L + ++ IE AF GL + L L
Sbjct: 59 SNFYHL-NFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNN 117
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+L L DTF G+ + L + + I+ G+F+ L + L + +N I + + ++ +
Sbjct: 118 ELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPD-NIFR 176
Query: 332 NNSVRVFKLTGNHMLESPEAVVLE----VENIIIRGNHLPCECGRDPFTNPLALS--QDF 385
S+ + GN + + P VLE V + + N C C P L +
Sbjct: 177 FASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIY 236
Query: 386 AEENYCISPLKVRGRSL 402
E C +P + GR L
Sbjct: 237 IGEAICETPSDLYGRLL 253
Score = 34.7 bits (76), Expect = 0.68
Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
GLS ++ QL L+ +L++LR+D F + L L D + I AF L +L+ L +
Sbjct: 105 GLS-ALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILN 163
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQI 205
++ + F ++T + + NRI ++
Sbjct: 164 DNLISFLPDNIF-RFASLTHLDIRGNRIQKL 193
Score = 34.3 bits (75), Expect = 0.90
Identities = 23/103 (22%), Positives = 44/103 (42%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+ I+ ++ F EG+ +L L + + D FH L + RL L + + + F
Sbjct: 387 NSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFS 446
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
GL ++ L + N I I + ++++ L N + P
Sbjct: 447 GLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP 489
>BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein.
Length = 743
Score = 60.5 bits (140), Expect = 1e-08
Identities = 36/140 (25%), Positives = 62/140 (44%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C S+V C +L VP+G++ V +++L ++ L +FA L +L L + +
Sbjct: 33 CYVPSEVHCTFRSLASVPAGIAKHVERINLGFNSIQALSETSFAGLTKLELLMIHGNEIP 92
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
I A R L L+ + L + L N+ + + HN+I I AF G
Sbjct: 93 SIPDGALRDLSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTS 152
Query: 216 INLISLRNNPIKRILVHAFS 235
+ L+ L N + ++ FS
Sbjct: 153 LRLLHLEGNLLHQLHPSTFS 172
Score = 37.1 bits (82), Expect = 0.13
Identities = 35/167 (20%), Positives = 73/167 (43%), Gaps = 12/167 (7%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
+ I+L N I+ + +F+GL + + + I +I A L + V + ++ L
Sbjct: 57 VERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLR 116
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE-------- 326
+ T GL + RL + + + I +F+GL + L + N + +
Sbjct: 117 VITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTF 176
Query: 327 LSLVQNNSVRVFKLTGNHMLESPEAVVLE---VENIIIRGNHLPCEC 370
L + +++R L N + P +++ +EN+ ++GN C+C
Sbjct: 177 LDYFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYLQGNPWTCDC 223
>AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein
protein.
Length = 689
Score = 60.5 bits (140), Expect = 1e-08
Identities = 36/124 (29%), Positives = 62/124 (50%), Gaps = 2/124 (1%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + V++ D F +L LRRL L+ + R+ P F GL L+ LY+++ + +
Sbjct: 258 LHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEIS 317
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH-AFSGLNDVG 241
+ F ++ N+ + L +N + + Y F+G L +LRNN + V L +
Sbjct: 318 AGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARL-NLRNNKFMYLPVSGVLDQLQSLT 376
Query: 242 QIEL 245
QI+L
Sbjct: 377 QIDL 380
Score = 47.6 bits (108), Expect = 9e-05
Identities = 29/99 (29%), Positives = 46/99 (46%)
Query: 138 FAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVL 197
F L L L + +T I+ F L LR LY+ + + F+ L N+ + L
Sbjct: 249 FTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYL 308
Query: 198 THNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSG 236
+N I +I + F + L+ L NN +K + V+ FSG
Sbjct: 309 EYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG 347
Score = 43.2 bits (97), Expect = 0.002
Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 3/156 (1%)
Query: 169 RELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKR 228
++L++ + VD F + + + L N+I I+ F + + L N I+R
Sbjct: 232 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 291
Query: 229 ILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV 287
+ FSGL+++ + L I+ I F + + +L L L SL F G +
Sbjct: 292 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG-APL 350
Query: 288 GRLSLRESDLGIIKV-GSFDGLQHVDTLEICNNKID 322
RL+LR + + V G D LQ + +++ N D
Sbjct: 351 ARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWD 386
Score = 34.3 bits (75), Expect = 0.90
Identities = 23/103 (22%), Positives = 44/103 (42%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+ I+ ++ F EG+ +L L + + D FH L + RL L + + + F
Sbjct: 239 NSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFS 298
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
GL ++ L + N I I + ++++ L N + P
Sbjct: 299 GLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP 341
>AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein.
Length = 837
Score = 60.5 bits (140), Expect = 1e-08
Identities = 36/124 (29%), Positives = 62/124 (50%), Gaps = 2/124 (1%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + V++ D F +L LRRL L+ + R+ P F GL L+ LY+++ + +
Sbjct: 406 LHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEIS 465
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH-AFSGLNDVG 241
+ F ++ N+ + L +N + + Y F+G L +LRNN + V L +
Sbjct: 466 AGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARL-NLRNNKFMYLPVSGVLDQLQSLT 524
Query: 242 QIEL 245
QI+L
Sbjct: 525 QIDL 528
Score = 47.6 bits (108), Expect = 9e-05
Identities = 29/99 (29%), Positives = 46/99 (46%)
Query: 138 FAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVL 197
F L L L + +T I+ F L LR LY+ + + F+ L N+ + L
Sbjct: 397 FTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYL 456
Query: 198 THNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSG 236
+N I +I + F + L+ L NN +K + V+ FSG
Sbjct: 457 EYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG 495
Score = 43.2 bits (97), Expect = 0.002
Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 3/156 (1%)
Query: 169 RELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKR 228
++L++ + VD F + + + L N+I I+ F + + L N I+R
Sbjct: 380 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 439
Query: 229 ILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV 287
+ FSGL+++ + L I+ I F + + +L L L SL F G +
Sbjct: 440 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG-APL 498
Query: 288 GRLSLRESDLGIIKV-GSFDGLQHVDTLEICNNKID 322
RL+LR + + V G D LQ + +++ N D
Sbjct: 499 ARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWD 534
Score = 42.7 bits (96), Expect = 0.003
Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 3/136 (2%)
Query: 186 FAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
F + S+ L +N++ IE AF G + + + L NN +K + F G+ ++ ++
Sbjct: 79 FLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQA 138
Query: 246 PSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIK-VG 303
I+ IE AF L + VL L +L S LPD + L +R + + + +G
Sbjct: 139 DYNLIKYIERGAFNKLHKLKVLILN-DNLISFLPDNIFRFASLTHLDIRGNRIQKLPYIG 197
Query: 304 SFDGLQHVDTLEICNN 319
+ + V L++ +N
Sbjct: 198 VLEHIGRVVELQLEDN 213
Score = 41.5 bits (93), Expect = 0.006
Identities = 48/197 (24%), Positives = 86/197 (43%), Gaps = 9/197 (4%)
Query: 213 TNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFM 271
+NF +L + +NN + + + F + + L + ++ IE AF GL + L L
Sbjct: 59 SNFYHL-NFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNN 117
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
+L L DTF G+ + L + + I+ G+F+ L + L + +N I + + ++ +
Sbjct: 118 ELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPD-NIFR 176
Query: 332 NNSVRVFKLTGNHMLESPEAVVLE----VENIIIRGNHLPCECGRDPFTNPLALS--QDF 385
S+ + GN + + P VLE V + + N C C P L +
Sbjct: 177 FASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIY 236
Query: 386 AEENYCISPLKVRGRSL 402
E C +P + GR L
Sbjct: 237 IGEAICETPSDLYGRLL 253
Score = 34.7 bits (76), Expect = 0.68
Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
GLS ++ QL L+ +L++LR+D F + L L D + I AF L +L+ L +
Sbjct: 105 GLS-ALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILN 163
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQI 205
++ + F ++T + + NRI ++
Sbjct: 164 DNLISFLPDNIF-RFASLTHLDIRGNRIQKL 193
Score = 34.3 bits (75), Expect = 0.90
Identities = 23/103 (22%), Positives = 44/103 (42%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+ I+ ++ F EG+ +L L + + D FH L + RL L + + + F
Sbjct: 387 NSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFS 446
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
GL ++ L + N I I + ++++ L N + P
Sbjct: 447 GLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP 489
>AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens
cDNA FLJ33057 fis, clone TRACH1000144, weakly similar to
CHONDROADHERIN PRECURSOR. ).
Length = 469
Score = 60.5 bits (140), Expect = 1e-08
Identities = 36/124 (29%), Positives = 62/124 (50%), Gaps = 2/124 (1%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
L L + V++ D F +L LRRL L+ + R+ P F GL L+ LY+++ + +
Sbjct: 38 LHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEIS 97
Query: 183 SFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVH-AFSGLNDVG 241
+ F ++ N+ + L +N + + Y F+G L +LRNN + V L +
Sbjct: 98 AGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARL-NLRNNKFMYLPVSGVLDQLQSLT 156
Query: 242 QIEL 245
QI+L
Sbjct: 157 QIDL 160
Score = 47.6 bits (108), Expect = 9e-05
Identities = 29/99 (29%), Positives = 46/99 (46%)
Query: 138 FAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVL 197
F L L L + +T I+ F L LR LY+ + + F+ L N+ + L
Sbjct: 29 FTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYL 88
Query: 198 THNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSG 236
+N I +I + F + L+ L NN +K + V+ FSG
Sbjct: 89 EYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG 127
Score = 43.2 bits (97), Expect = 0.002
Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 3/156 (1%)
Query: 169 RELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKR 228
++L++ + VD F + + + L N+I I+ F + + L N I+R
Sbjct: 12 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 71
Query: 229 ILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV 287
+ FSGL+++ + L I+ I F + + +L L L SL F G +
Sbjct: 72 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSG-APL 130
Query: 288 GRLSLRESDLGIIKV-GSFDGLQHVDTLEICNNKID 322
RL+LR + + V G D LQ + +++ N D
Sbjct: 131 ARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWD 166
Score = 34.3 bits (75), Expect = 0.90
Identities = 23/103 (22%), Positives = 44/103 (42%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+ I+ ++ F EG+ +L L + + D FH L + RL L + + + F
Sbjct: 19 NSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFS 78
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
GL ++ L + N I I + ++++ L N + P
Sbjct: 79 GLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP 121
>AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein.
Length = 802
Score = 60.1 bits (139), Expect = 2e-08
Identities = 61/247 (24%), Positives = 113/247 (45%), Gaps = 14/247 (5%)
Query: 112 VPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLREL 171
V + L PS+ +LSL +++ + + L+ L L +C+L RI P + L L EL
Sbjct: 555 VVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERI-PHSIFSLNNLHEL 613
Query: 172 YIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILV 231
++ L TV+ +F LQN++ + L HN IA I + A +N + +SL +N I+ + +
Sbjct: 614 DLRENNLKTVEEISFQHLQNLSCLKLWHNNIAYIPAQIGALSN-LEQLSLDHNNIENLPL 672
Query: 232 HAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLS 291
F + ++L T P+ L + + ++ +LPD ++ L
Sbjct: 673 QLFL-CTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNI-EMLPDGLFQCKKLQCLL 730
Query: 292 LRESDLGIIK--VGSFDGLQHVDT----LEICNNKIDGIEELS----LVQNNSVRVFKLT 341
L ++ L + VG L H++ LE +++G + L +V+ N + L
Sbjct: 731 LGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLP 790
Query: 342 GNHMLES 348
L++
Sbjct: 791 VTERLQT 797
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 60.1 bits (139), Expect = 2e-08
Identities = 36/140 (25%), Positives = 62/140 (44%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C S+V C +L VP+G++ V +++L ++ L +FA L +L L + +
Sbjct: 33 CYVPSEVHCTFRSLASVPAGIARHVERINLGFNSIQALSETSFAGLTKLELLMIHGNEIP 92
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
I A R L L+ + L + L N+ + + HN+I I AF G
Sbjct: 93 SIPDGALRDLSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTS 152
Query: 216 INLISLRNNPIKRILVHAFS 235
+ L+ L N + ++ FS
Sbjct: 153 LRLLHLEGNLLHQLHPSTFS 172
Score = 37.1 bits (82), Expect = 0.13
Identities = 35/167 (20%), Positives = 73/167 (43%), Gaps = 12/167 (7%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
+ I+L N I+ + +F+GL + + + I +I A L + V + ++ L
Sbjct: 57 VERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLR 116
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE-------- 326
+ T GL + RL + + + I +F+GL + L + N + +
Sbjct: 117 VITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTF 176
Query: 327 LSLVQNNSVRVFKLTGNHMLESPEAVVLE---VENIIIRGNHLPCEC 370
L + +++R L N + P +++ +EN+ ++GN C+C
Sbjct: 177 LDYFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYLQGNPWTCDC 223
>AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein.
Length = 700
Score = 60.1 bits (139), Expect = 2e-08
Identities = 47/161 (29%), Positives = 78/161 (48%), Gaps = 3/161 (1%)
Query: 107 AALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLP 166
AA+R S+ L+LSR + + + AFA LR LR L LD+ L +R RGL
Sbjct: 7 AAVRRRDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLG 66
Query: 167 RLRELYIQHTPLATVDSFAF-AALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNP 225
LR L + + + V+S AF A L + + L++N + + A +N ++L +N
Sbjct: 67 NLRHLILGNNQIRRVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNL 126
Query: 226 IKRILVHAFSGLNDVGQIELPSG-IRTIEPQA-FAGLEGIG 264
I I F L+ + ++++ S + + P F +G G
Sbjct: 127 IDHIAEGTFVQLHKLVRLDMTSNRLHKLPPDGLFLRSQGTG 167
Score = 42.7 bits (96), Expect = 0.003
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 2/152 (1%)
Query: 130 LRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAAL 189
+ +R FA++ L L L + ++ AF L LR L++ LA V L
Sbjct: 6 IAAVRRRDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGL 65
Query: 190 QNITSIVLTHNRIAQIESYAF-AGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG 248
N+ ++L +N+I ++ES AF A + + + L N ++ + A + ++ + L
Sbjct: 66 GNLRHLILGNNQIRRVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHN 125
Query: 249 -IRTIEPQAFAGLEGIGVLELAFMDLPSLLPD 279
I I F L + L++ L L PD
Sbjct: 126 LIDHIAEGTFVQLHKLVRLDMTSNRLHKLPPD 157
>AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein.
Length = 627
Score = 58.8 bits (136), Expect = 4e-08
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 3/134 (2%)
Query: 123 LSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVD 182
LSLSR +R + + AFA LR LR L LD LT + RGL LR L + + LA +
Sbjct: 88 LSLSRNTIRHVAAGAFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALA 147
Query: 183 SFAF-AALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVG 241
+ A + + + L++N + Q+ A +N + L +N + + AFS L+ +
Sbjct: 148 AGALDDCAETLEDLDLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASV-PGAFSRLHKLA 206
Query: 242 QIELPSG-IRTIEP 254
++++ S + TI P
Sbjct: 207 RLDMTSNRLTTIPP 220
Score = 54.8 bits (126), Expect = 6e-07
Identities = 44/188 (23%), Positives = 83/188 (44%), Gaps = 4/188 (2%)
Query: 96 CLSQS---QVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDAC 152
C +QS V+C A L VP L +L L+ + +R A++ L L+L
Sbjct: 34 CQTQSLPLSVLCPGAGLLFVPPSLDRRAAELRLADNFIASVRRRDLANMTGLLHLSLSRN 93
Query: 153 NLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAG 212
+ + AF L LR L++ L ++ L N+ ++L++N++A + + A
Sbjct: 94 TIRHVAAGAFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALAAGALDD 153
Query: 213 -TNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLELAFM 271
+ + L N ++++ A L +V + L + P AF+ L + L++
Sbjct: 154 CAETLEDLDLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVPGAFSRLHKLARLDMTSN 213
Query: 272 DLPSLLPD 279
L ++ PD
Sbjct: 214 RLTTIPPD 221
Score = 33.5 bits (73), Expect = 1.6
Identities = 26/104 (25%), Positives = 45/104 (43%), Gaps = 1/104 (0%)
Query: 249 IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDG- 307
IR + AFA L + L L L SL GL+ + L L + L + G+ D
Sbjct: 95 IRHVAAGAFADLRALRALHLDGNRLTSLGEGQLRGLVNLRHLILSNNQLAALAAGALDDC 154
Query: 308 LQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEA 351
+ ++ L++ N ++ + +L + +V L N + P A
Sbjct: 155 AETLEDLDLSYNNLEQLPWEALGRLGNVNTLGLDHNLLASVPGA 198
>AL137848-6|CAI16698.1| 243|Homo sapiens asporin (LRR class 1)
protein.
Length = 243
Score = 58.8 bits (136), Expect = 4e-08
Identities = 34/132 (25%), Positives = 64/132 (48%), Gaps = 4/132 (3%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C S+VV C+ L VP+ + L L ++ ++ + F L L L L+ L
Sbjct: 79 CQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKL 138
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T+I P AF +LR LY+ H L+ + +++ + + N++ +I+ F G N
Sbjct: 139 TKIHPKAFLTTKKLRRLYLSHNQLSEI---PLNLPKSLAELRIHENKVKKIQKDTFKGMN 195
Query: 215 FINLISLRNNPI 226
++++ + NP+
Sbjct: 196 ALHVLEMSANPL 207
Score = 35.1 bits (77), Expect = 0.52
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 12/114 (10%)
Query: 218 LISLRNNPIKRILVHAFSGLNDV-GQIELPSGIRTIEPQAFAGLEGIGVLELA---FMDL 273
++ L+NN IK I + F GL + G I + + I P+AF + + L L+ ++
Sbjct: 106 MLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEI 165
Query: 274 PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID--GIE 325
P LP + + L + E+ + I+ +F G+ + LE+ N +D GIE
Sbjct: 166 PLNLPKS------LAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIE 213
>AK027359-1|BAB55060.1| 246|Homo sapiens protein ( Homo sapiens
cDNA FLJ14453 fis, clone HEMBB1001871, weakly similar to
BONE/CARTILAGE PROTEOGLYCAN I PRECURSOR. ).
Length = 246
Score = 58.8 bits (136), Expect = 4e-08
Identities = 34/132 (25%), Positives = 64/132 (48%), Gaps = 4/132 (3%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNL 154
C S+VV C+ L VP+ + L L ++ ++ + F L L L L+ L
Sbjct: 82 CQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKL 141
Query: 155 TRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTN 214
T+I P AF +LR LY+ H L+ + +++ + + N++ +I+ F G N
Sbjct: 142 TKIHPKAFLTTKKLRRLYLSHNQLSEI---PLNLPKSLAELRIHENKVKKIQKDTFKGMN 198
Query: 215 FINLISLRNNPI 226
++++ + NP+
Sbjct: 199 ALHVLEMSANPL 210
Score = 35.1 bits (77), Expect = 0.52
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 12/114 (10%)
Query: 218 LISLRNNPIKRILVHAFSGLNDV-GQIELPSGIRTIEPQAFAGLEGIGVLELA---FMDL 273
++ L+NN IK I + F GL + G I + + I P+AF + + L L+ ++
Sbjct: 109 MLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEI 168
Query: 274 PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID--GIE 325
P LP + + L + E+ + I+ +F G+ + LE+ N +D GIE
Sbjct: 169 PLNLPKS------LAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIE 216
>AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 variant
protein.
Length = 627
Score = 58.8 bits (136), Expect = 4e-08
Identities = 38/158 (24%), Positives = 78/158 (49%), Gaps = 2/158 (1%)
Query: 172 YIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILV 231
Y+Q+ + ++ +AF L ++T + L+HNRI ++ F + + + + +N + RI
Sbjct: 26 YLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISP 85
Query: 232 HAFSGLNDVGQIELPSGIRTIEPQ--AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GLN + + L + + T P + + L+L + +L TF +
Sbjct: 86 PTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTV 145
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEEL 327
L +R++ + + +F LQ +D L++ +NKI+ + L
Sbjct: 146 LVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPL 183
Score = 50.4 bits (115), Expect = 1e-05
Identities = 40/174 (22%), Positives = 75/174 (43%), Gaps = 2/174 (1%)
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+T I +AFRGL L +LY+ H + + F L + +++ N +++I F G
Sbjct: 32 ITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGL 91
Query: 214 NFINLISLRNNPIKRILVHAF-SGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFM 271
N + L+ L NN + R+ + + ++L I + F + VL +
Sbjct: 92 NSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKN 151
Query: 272 DLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIE 325
+ L +TF L ++ L L + + + F L+ + L + N I I+
Sbjct: 152 KINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQ 205
Score = 43.2 bits (97), Expect = 0.002
Identities = 43/179 (24%), Positives = 82/179 (45%), Gaps = 8/179 (4%)
Query: 193 TSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRT 251
T + T N A ++S + N L L+NN I I ++AF GLN + ++ L + I
Sbjct: 2 TMVTCTQNMKAALKSLLYHSRN---LGYLQNNKITSISIYAFRGLNSLTKLYLSHNRITF 58
Query: 252 IEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSF-DGLQH 310
++P F L + L + L + P TF+GL + L L + L + +
Sbjct: 59 LKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPR 118
Query: 311 VDTLEICNNKIDGIEELSLVQNNSVRVF---KLTGNHMLESPEAVVLEVENIIIRGNHL 366
+ L++ N I + L+ + +++ V K NH+ E+ A + +++ + + N +
Sbjct: 119 LHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKI 177
Score = 39.5 bits (88), Expect = 0.024
Identities = 31/147 (21%), Positives = 63/147 (42%), Gaps = 1/147 (0%)
Query: 115 GLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQ 174
GL+ + + ++ R+ H+ +L L L+ ++ +R F L L ++
Sbjct: 90 GLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMR 149
Query: 175 HTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAF 234
+ ++ FA LQ + + L N+I + F ++ ++L NPI++I + F
Sbjct: 150 KNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQF 209
Query: 235 SGLNDVGQIELPS-GIRTIEPQAFAGL 260
L + + L I I+ + F L
Sbjct: 210 DYLVKLKSLSLEGIEISNIQQRMFRPL 236
>BC040879-1|AAH40879.1| 493|Homo sapiens adhesion molecule with
Ig-like domain 1 protein.
Length = 493
Score = 58.4 bits (135), Expect = 5e-08
Identities = 43/135 (31%), Positives = 62/135 (45%), Gaps = 2/135 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSD-AFAHLRQLRRLALDACN 153
CL S ++ C+ L VP L L LS +L LR++ L QL L L +
Sbjct: 38 CLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNH 97
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
L I AF +P LR L + L T+D F F+ LQ + ++L +N I ++ AF
Sbjct: 98 LNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDM 157
Query: 214 NFINLISLRNNPIKR 228
+ + L N I R
Sbjct: 158 AQLQKLYLSQNQISR 172
>AY237007-1|AAO48948.1| 493|Homo sapiens transmembrane protein
AMIGO protein.
Length = 493
Score = 58.4 bits (135), Expect = 5e-08
Identities = 43/135 (31%), Positives = 62/135 (45%), Gaps = 2/135 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSD-AFAHLRQLRRLALDACN 153
CL S ++ C+ L VP L L LS +L LR++ L QL L L +
Sbjct: 38 CLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNH 97
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
L I AF +P LR L + L T+D F F+ LQ + ++L +N I ++ AF
Sbjct: 98 LNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDM 157
Query: 214 NFINLISLRNNPIKR 228
+ + L N I R
Sbjct: 158 AQLQKLYLSQNQISR 172
>AL355145-6|CAI22942.1| 493|Homo sapiens adhesion molecule with
Ig-like domain 1 protein.
Length = 493
Score = 58.4 bits (135), Expect = 5e-08
Identities = 43/135 (31%), Positives = 62/135 (45%), Gaps = 2/135 (1%)
Query: 96 CLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSD-AFAHLRQLRRLALDACN 153
CL S ++ C+ L VP L L LS +L LR++ L QL L L +
Sbjct: 38 CLCASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNH 97
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
L I AF +P LR L + L T+D F F+ LQ + ++L +N I ++ AF
Sbjct: 98 LNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDM 157
Query: 214 NFINLISLRNNPIKR 228
+ + L N I R
Sbjct: 158 AQLQKLYLSQNQISR 172
>DQ355157-1|ABC79623.1| 334|Homo sapiens cytokeratin associated
protein protein.
Length = 334
Score = 58.0 bits (134), Expect = 6e-08
Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 1/129 (0%)
Query: 192 ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IR 250
+ +++L HNR+ + AFAG + + LR N + + V AF GL + ++L + +
Sbjct: 73 LRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLE 132
Query: 251 TIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQH 310
+ P FA L + L LA L L P L + LSL++++L + G L
Sbjct: 133 ALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPA 192
Query: 311 VDTLEICNN 319
+D L + N
Sbjct: 193 LDALHLRGN 201
Score = 57.2 bits (132), Expect = 1e-07
Identities = 39/131 (29%), Positives = 62/131 (47%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C+ C++ +L VP GLS + L L +R L AFA L+RL L L
Sbjct: 49 CVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLH 108
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ AF GL L+ L + L + FA L+ + ++ L NR+A++E A
Sbjct: 109 SVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPL 168
Query: 216 INLISLRNNPI 226
+ +SL++N +
Sbjct: 169 LRSLSLQDNEL 179
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/129 (23%), Positives = 66/129 (51%), Gaps = 1/129 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLP 274
+ + L +N ++ + AF+G + +++L +G+ ++ +AF GL + +L+L+ L
Sbjct: 73 LRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLE 132
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
+L P TF L + LSL + L ++ + L + +L + +N++ + L + +
Sbjct: 133 ALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPA 192
Query: 335 VRVFKLTGN 343
+ L GN
Sbjct: 193 LDALHLRGN 201
Score = 42.7 bits (96), Expect = 0.003
Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
RLR L + H + + AFA + + L N + + AF G + L+ L N +
Sbjct: 72 RLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQL 131
Query: 227 KRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLI 285
+ + F+ L + + L + +EP A L + L L +L +L P L
Sbjct: 132 EALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLP 191
Query: 286 RVGRLSLRESDLG 298
+ L LR + G
Sbjct: 192 ALDALHLRGNPWG 204
>BC114551-1|AAI14552.1| 334|Homo sapiens ISLR2 protein protein.
Length = 334
Score = 58.0 bits (134), Expect = 6e-08
Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 6/124 (4%)
Query: 104 CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFR 163
C LR VP GL +VT LSLS + VLR AFA + Q+ L L + + P A
Sbjct: 37 CAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALA 96
Query: 164 GLPRLRELYIQHTPLATVDSFAFAALQNITSIVL---THNRIAQIESYAFAGTNFINLIS 220
L +L+ L + H + SF ++ L+N++++ L HNR+ + A + +
Sbjct: 97 VLSQLKNLDLSHN---FISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLR 153
Query: 221 LRNN 224
+ NN
Sbjct: 154 INNN 157
Score = 41.5 bits (93), Expect = 0.006
Identities = 23/99 (23%), Positives = 48/99 (48%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L+L A +T +R AF + ++ L++ H + TV+ A A L + ++ L+HN I+
Sbjct: 56 LSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFP 115
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
+ + L+ + +N + + A L D+ + +
Sbjct: 116 WSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRI 154
Score = 35.9 bits (79), Expect = 0.30
Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLP 274
+ +SL N I + AF+ + V + L +RT+EP A A L + L+L+ +
Sbjct: 53 VTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFIS 112
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDG 323
S L + L + + LG + + L + +L I NN++ G
Sbjct: 113 SFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLAG 161
>BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 5 protein.
Length = 719
Score = 58.0 bits (134), Expect = 6e-08
Identities = 39/129 (30%), Positives = 65/129 (50%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L+LSR + + AFA LR LR L L++ LT+I F GL L L + + L
Sbjct: 76 SLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQL 135
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ S AF + + + L++N + I A ++ +SL +N I I FS L+
Sbjct: 136 TLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLH 195
Query: 239 DVGQIELPS 247
+ ++++ S
Sbjct: 196 KMTRLDVTS 204
Score = 57.6 bits (133), Expect = 8e-08
Identities = 49/205 (23%), Positives = 93/205 (45%), Gaps = 11/205 (5%)
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
R EL + + + FA + ++ + L+ N I+ I +AFA + + L +N +
Sbjct: 52 RTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 111
Query: 227 KRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLI 285
+I FSGL+++ + L + + I AF + + L+L++ +L ++ D ++
Sbjct: 112 TKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMV 171
Query: 286 RVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ LSL + + I G+F L + L++ +NK+ + L Q +V +G
Sbjct: 172 SLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQR--AQVLATSG--- 226
Query: 346 LESPEAVVLEVENIIIRGNHLPCEC 370
+ SP L GN L C C
Sbjct: 227 IISPSTFALS-----FGGNPLHCNC 246
Score = 48.8 bits (111), Expect = 4e-05
Identities = 34/145 (23%), Positives = 71/145 (48%), Gaps = 1/145 (0%)
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+T I+ F + L +L + ++ + AFA L+N+ ++ L NR+ +I + F+G
Sbjct: 63 VTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGL 122
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMD 272
+ ++ + L NN + I AF + + +++L + + TI A + + L L
Sbjct: 123 SNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNM 182
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDL 297
+ ++ TF L ++ RL + + L
Sbjct: 183 IDNIPKGTFSHLHKMTRLDVTSNKL 207
>AL929554-11|CAH72880.1| 334|Homo sapiens leucine rich repeat
containing 26 protein.
Length = 334
Score = 58.0 bits (134), Expect = 6e-08
Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 1/129 (0%)
Query: 192 ITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IR 250
+ +++L HNR+ + AFAG + + LR N + + V AF GL + ++L + +
Sbjct: 73 LRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLE 132
Query: 251 TIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQH 310
+ P FA L + L LA L L P L + LSL++++L + G L
Sbjct: 133 ALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPA 192
Query: 311 VDTLEICNN 319
+D L + N
Sbjct: 193 LDALHLRGN 201
Score = 57.2 bits (132), Expect = 1e-07
Identities = 39/131 (29%), Positives = 62/131 (47%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C+ C++ +L VP GLS + L L +R L AFA L+RL L L
Sbjct: 49 CVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLH 108
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ AF GL L+ L + L + FA L+ + ++ L NR+A++E A
Sbjct: 109 SVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPL 168
Query: 216 INLISLRNNPI 226
+ +SL++N +
Sbjct: 169 LRSLSLQDNEL 179
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/129 (23%), Positives = 66/129 (51%), Gaps = 1/129 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLP 274
+ + L +N ++ + AF+G + +++L +G+ ++ +AF GL + +L+L+ L
Sbjct: 73 LRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLE 132
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNS 334
+L P TF L + LSL + L ++ + L + +L + +N++ + L + +
Sbjct: 133 ALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPA 192
Query: 335 VRVFKLTGN 343
+ L GN
Sbjct: 193 LDALHLRGN 201
Score = 42.7 bits (96), Expect = 0.003
Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 1/133 (0%)
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
RLR L + H + + AFA + + L N + + AF G + L+ L N +
Sbjct: 72 RLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQL 131
Query: 227 KRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLI 285
+ + F+ L + + L + +EP A L + L L +L +L P L
Sbjct: 132 EALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLP 191
Query: 286 RVGRLSLRESDLG 298
+ L LR + G
Sbjct: 192 ALDALHLRGNPWG 204
>AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 58.0 bits (134), Expect = 6e-08
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 5/209 (2%)
Query: 125 LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSF 184
LS +L L+ F HLR L L L +L+ I AF GL L+ L +Q+ L + +
Sbjct: 30 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 89
Query: 185 AFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIE 244
A L ++ S+ L +N++ + A + + NN IK I AF G + I
Sbjct: 90 ALWELPSLQSLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIH 148
Query: 245 L-PSGIRTIEPQAFAGLEGIGVLEL-AFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKV 302
+ I+ + AF L + L L MD+ PD G + L+L + + ++
Sbjct: 149 FYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQE-FPD-LKGTTSLEILTLTRAGIRLLPS 206
Query: 303 GSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
G L + LE+ +N+I+ + L Q
Sbjct: 207 GMCQQLPRLRVLELSHNQIEELPSLHRCQ 235
Score = 45.6 bits (103), Expect = 4e-04
Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
LPRLR L + H + + S Q + I L HNRI +I + F+ + + + L N
Sbjct: 212 LPRLRVLELSHNQIEELPSLH--RCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 269
Query: 225 PIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
I+ I AFS L+ + +++L T P AGL G+ L+L
Sbjct: 270 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKL 311
Score = 41.1 bits (92), Expect = 0.008
Identities = 42/163 (25%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
AF +L +L L+L+ + P +G L L + + + S L + +
Sbjct: 161 AFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLE 219
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQ 255
L+HN+I ++ S + I L++N I I FS L+ + ++L + IR+I P+
Sbjct: 220 LSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPE 277
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV---GRLSLRES 295
AF+ L + L+L L +L GL+ + G L+L ++
Sbjct: 278 AFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQA 320
Score = 38.3 bits (85), Expect = 0.055
Identities = 26/86 (30%), Positives = 42/86 (48%)
Query: 267 ELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
+L+ +L L P FH L + L L + L I +F GL + L + NN++ GI
Sbjct: 29 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 88
Query: 327 LSLVQNNSVRVFKLTGNHMLESPEAV 352
+L + S++ L N + E P A+
Sbjct: 89 EALWELPSLQSLDLNYNKLQEFPVAI 114
>AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens
cDNA FLJ30803 fis, clone FEBRA2001245, weakly similar to
NAG14. ).
Length = 719
Score = 58.0 bits (134), Expect = 6e-08
Identities = 39/129 (30%), Positives = 65/129 (50%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L+LSR + + AFA LR LR L L++ LT+I F GL L L + + L
Sbjct: 76 SLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQL 135
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ S AF + + + L++N + I A ++ +SL +N I I FS L+
Sbjct: 136 TLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLH 195
Query: 239 DVGQIELPS 247
+ ++++ S
Sbjct: 196 KMTRLDVTS 204
Score = 57.6 bits (133), Expect = 8e-08
Identities = 49/205 (23%), Positives = 93/205 (45%), Gaps = 11/205 (5%)
Query: 167 RLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
R EL + + + FA + ++ + L+ N I+ I +AFA + + L +N +
Sbjct: 52 RTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 111
Query: 227 KRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLI 285
+I FSGL+++ + L + + I AF + + L+L++ +L ++ D ++
Sbjct: 112 TKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMV 171
Query: 286 RVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHM 345
+ LSL + + I G+F L + L++ +NK+ + L Q +V +G
Sbjct: 172 SLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQR--AQVLATSG--- 226
Query: 346 LESPEAVVLEVENIIIRGNHLPCEC 370
+ SP L GN L C C
Sbjct: 227 IISPSTFALS-----FGGNPLHCNC 246
Score = 48.8 bits (111), Expect = 4e-05
Identities = 34/145 (23%), Positives = 71/145 (48%), Gaps = 1/145 (0%)
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+T I+ F + L +L + ++ + AFA L+N+ ++ L NR+ +I + F+G
Sbjct: 63 VTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGL 122
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQAFAGLEGIGVLELAFMD 272
+ ++ + L NN + I AF + + +++L + + TI A + + L L
Sbjct: 123 SNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNM 182
Query: 273 LPSLLPDTFHGLIRVGRLSLRESDL 297
+ ++ TF L ++ RL + + L
Sbjct: 183 IDNIPKGTFSHLHKMTRLDVTSNKL 207
>AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 58.0 bits (134), Expect = 6e-08
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 5/209 (2%)
Query: 125 LSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSF 184
LS +L L+ F HLR L L L +L+ I AF GL L+ L +Q+ L + +
Sbjct: 30 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 89
Query: 185 AFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIE 244
A L ++ S+ L +N++ + A + + NN IK I AF G + I
Sbjct: 90 ALWELPSLQSLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIH 148
Query: 245 L-PSGIRTIEPQAFAGLEGIGVLEL-AFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKV 302
+ I+ + AF L + L L MD+ PD G + L+L + + ++
Sbjct: 149 FYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQE-FPD-LKGTTSLEILTLTRAGIRLLPS 206
Query: 303 GSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
G L + LE+ +N+I+ + L Q
Sbjct: 207 GMCQQLPRLRVLELSHNQIEELPSLHRCQ 235
Score = 45.6 bits (103), Expect = 4e-04
Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 165 LPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN 224
LPRLR L + H + + S Q + I L HNRI +I + F+ + + + L N
Sbjct: 212 LPRLRVLELSHNQIEELPSLH--RCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWN 269
Query: 225 PIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGLEGIGVLEL 268
I+ I AFS L+ + +++L T P AGL G+ L+L
Sbjct: 270 AIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGLGGLMHLKL 311
Score = 41.1 bits (92), Expect = 0.008
Identities = 42/163 (25%), Positives = 76/163 (46%), Gaps = 7/163 (4%)
Query: 137 AFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIV 196
AF +L +L L+L+ + P +G L L + + + S L + +
Sbjct: 161 AFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLE 219
Query: 197 LTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELP-SGIRTIEPQ 255
L+HN+I ++ S + I L++N I I FS L+ + ++L + IR+I P+
Sbjct: 220 LSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPE 277
Query: 256 AFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV---GRLSLRES 295
AF+ L + L+L L +L GL+ + G L+L ++
Sbjct: 278 AFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQA 320
Score = 38.3 bits (85), Expect = 0.055
Identities = 26/86 (30%), Positives = 42/86 (48%)
Query: 267 ELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEE 326
+L+ +L L P FH L + L L + L I +F GL + L + NN++ GI
Sbjct: 29 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 88
Query: 327 LSLVQNNSVRVFKLTGNHMLESPEAV 352
+L + S++ L N + E P A+
Sbjct: 89 EALWELPSLQSLDLNYNKLQEFPVAI 114
>AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 380
Score = 57.6 bits (133), Expect = 8e-08
Identities = 36/146 (24%), Positives = 68/146 (46%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFA 161
V C+ L+ +P + + +L L+ ++ + + FA L+QLR L L + + A
Sbjct: 45 VDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGA 104
Query: 162 FRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISL 221
F + L L + + + AF ++ ++ L N+I+ IE AF + +++L
Sbjct: 105 FDDMKELERLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTL 164
Query: 222 RNNPIKRILVHAFSGLNDVGQIELPS 247
NN I I V +F+ + + L S
Sbjct: 165 NNNNITTIPVSSFNHMPKLRTFRLHS 190
Score = 53.2 bits (122), Expect = 2e-06
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 95 ICLSQSQVV-CNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACN 153
+C + +V C L +P+ L ++T++ L ++ + AF+ R+LRR+ L
Sbjct: 261 MCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQ 320
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAF 210
+ I P AF+GL L L + + + F L + ++L N+I I AF
Sbjct: 321 IAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAF 377
Score = 52.8 bits (121), Expect = 2e-06
Identities = 40/172 (23%), Positives = 71/172 (41%), Gaps = 3/172 (1%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+ I I FAGL+ + VL+L + ++ F + + RL L E+ + I +F
Sbjct: 71 NNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIPRKAFR 130
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAV---VLEVENIIIRG 363
G + L++ N+I IEE + + V L N++ P + + ++ +
Sbjct: 131 GATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHS 190
Query: 364 NHLPCECGRDPFTNPLALSQDFAEENYCISPLKVRGRSLASATSGSAGCRGE 415
NHL C+C + L C P +RG ++A C G+
Sbjct: 191 NHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQ 242
Score = 51.2 bits (117), Expect = 7e-06
Identities = 34/128 (26%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
+ L N I RI + F+GL + ++L I +E AF ++ + L+L+ + ++
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIP 125
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRV 337
F G + L L ++ + I+ G+F L+ ++ L + NN I I S +R
Sbjct: 126 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 185
Query: 338 FKLTGNHM 345
F+L NH+
Sbjct: 186 FRLHSNHL 193
Score = 50.8 bits (116), Expect = 1e-05
Identities = 36/117 (30%), Positives = 53/117 (45%), Gaps = 1/117 (0%)
Query: 142 RQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNR 201
R RL L+ N+TRI F GL +LR L + + V+ AF ++ + + L+ N
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENA 120
Query: 202 IAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIEPQAF 257
I I AF G + + L N I I AF L + + L + I TI +F
Sbjct: 121 IQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 177
Score = 44.0 bits (99), Expect = 0.001
Identities = 35/126 (27%), Positives = 57/126 (45%), Gaps = 2/126 (1%)
Query: 114 SGLSPSVTQLSLSRADLRVLRSDAF-AHLRQ-LRRLALDACNLTRIRPFAFRGLPRLREL 171
SG P++ S D R A A+L + + + L+ + I P AF +LR +
Sbjct: 255 SGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRI 314
Query: 172 YIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILV 231
+ + +A + AF L+++ S+VL N+I + F G + L+ L N I I
Sbjct: 315 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 374
Query: 232 HAFSGL 237
AF L
Sbjct: 375 DAFQDL 380
Score = 38.3 bits (85), Expect = 0.055
Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
Query: 242 QIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIK 301
++EL +GI++I P AF+ + ++L+ + + PD F GL + L L + + +
Sbjct: 291 RLEL-NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 349
Query: 302 VGSFDGLQHVDTLEICNNKIDGI 324
G F GL + L + NKI+ I
Sbjct: 350 RGVFGGLYTLQLLLLNANKINCI 372
Score = 37.9 bits (84), Expect = 0.073
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
Query: 190 QNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI 249
+ +T I L N I I AF+ + I L NN I I AF GL + + L
Sbjct: 285 ETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNK 344
Query: 250 RTIEPQ-AFAGLEGIGVLELAFMDLPSLLPDTFHGL 284
T P+ F GL + +L L + + PD F L
Sbjct: 345 ITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 380
Score = 35.5 bits (78), Expect = 0.39
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLL 277
I L N IK I AFS + +I+L + I I P AF GL + L L + L
Sbjct: 290 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 349
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGL 308
F GL + L L + + I+ +F L
Sbjct: 350 RGVFGGLYTLQLLLLNANKINCIRPDAFQDL 380
>AK001991-1|BAA92025.1| 273|Homo sapiens protein ( Homo sapiens
cDNA FLJ11129 fis, clone PLACE1006239, weakly similar to
BONE PROTEOGLYCAN II PRECURSOR. ).
Length = 273
Score = 57.6 bits (133), Expect = 8e-08
Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 1/146 (0%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++T L LS+ +L + + + QL + L+ LT + L L+ELYI H L
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLL 152
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+T+ AF L N+ + L NR+ I S F + ++ + NPI RI F L
Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212
Query: 239 DVGQIELPS-GIRTIEPQAFAGLEGI 263
++ + + + I A GLE +
Sbjct: 213 NLRSLVIAGINLTEIPDNALVGLENL 238
Score = 43.2 bits (97), Expect = 0.002
Identities = 29/108 (26%), Positives = 48/108 (44%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
++ +L L+ L+++ S F L L L + + RI+ F+ L LR L I L
Sbjct: 165 NLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINL 224
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPI 226
+ A L+N+ SI NR+ ++ A + + L NPI
Sbjct: 225 TEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPI 272
Score = 39.5 bits (88), Expect = 0.024
Identities = 35/170 (20%), Positives = 74/170 (43%), Gaps = 1/170 (0%)
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGI- 249
N+T + L+ N ++ + + + + L N + + S L+++ ++ + +
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLL 152
Query: 250 RTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQ 309
TI P AF GL + L L L + F L + L + E+ + IK +F L
Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212
Query: 310 HVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESPEAVVLEVENI 359
++ +L I + I + +LV ++ N +++ P + +V N+
Sbjct: 213 NLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNL 262
>Z29083-1|CAA82324.1| 420|Homo sapiens 5T4 oncofoetal antigen
protein.
Length = 420
Score = 57.2 bits (132), Expect = 1e-07
Identities = 60/219 (27%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAH---LRQLRRLALDACNLTRIR 158
V C + L VP+ L V L L+ L VL + AFA L +L L L L +R
Sbjct: 75 VKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVR 134
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINL 218
AF LP LR+L + H PLA + FAF+ + S+ + I ++ +
Sbjct: 135 AGAFEHLPSLRQLDLSHNPLADLSPFAFSG--SNASVSAPSPLVELILNHIVPPEDERQN 192
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ-AFAGLEGIGVLELAFMDLPSLL 277
S + +L A L + ++EL S P+ A L + L+L+ L SL
Sbjct: 193 RSFEGMVVAALL--AGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLT 250
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEI 316
+F L + L L ++ L ++ G+ LQ + + +
Sbjct: 251 YVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRV 289
Score = 45.6 bits (103), Expect = 4e-04
Identities = 50/191 (26%), Positives = 83/191 (43%), Gaps = 6/191 (3%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELY---IQHTPLATVDSFAFAALQNITSIVLTHN 200
+R L L L + AF P L EL + + L V + AF L ++ + L+HN
Sbjct: 93 VRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHN 152
Query: 201 RIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGL 260
+A + +AF+G+N +S + ++ IL H D Q G+ A L
Sbjct: 153 PLADLSPFAFSGSNAS--VSAPSPLVELILNHIVPP-EDERQNRSFEGMVVAALLAGRAL 209
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNK 320
+G+ LELA L D L + L L + L + SF L H+++L + +N
Sbjct: 210 QGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHLESLHLEDNA 269
Query: 321 IDGIEELSLVQ 331
+ + +L +
Sbjct: 270 LKVLHNGTLAE 280
>BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like family,
member 3 protein.
Length = 977
Score = 57.2 bits (132), Expect = 1e-07
Identities = 39/132 (29%), Positives = 67/132 (50%), Gaps = 10/132 (7%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L + ++ AF +L L+ L L+ ++ ++ P FRGL L LY + +
Sbjct: 433 SLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEFNVI 492
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN-----PIKRILVHA 233
+ AF+ + N+ + L +N + + + AFAGT+ L +LR N P+ +L H
Sbjct: 493 REIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLARL-NLRKNYFLYLPVAGVLEH- 550
Query: 234 FSGLNDVGQIEL 245
LN + QI+L
Sbjct: 551 ---LNAIVQIDL 559
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/117 (27%), Positives = 57/117 (48%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+L L R +R L +++F HL + L L I+ AF GL L+ LY+ L
Sbjct: 81 KLYLQRNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVF 140
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ F L+++ + +N I +IES AF + + ++ L +N I + + F ++
Sbjct: 141 RNDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAVS 197
Score = 43.6 bits (98), Expect = 0.001
Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
Query: 131 RVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQ 190
++ RSD F + L L L ++ ++ AF LP L+ L++ + + F LQ
Sbjct: 422 KIYRSD-FWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQ 480
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSG 236
++ + N I +I+ AF+ + L+ L NN ++ + AF+G
Sbjct: 481 SLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAG 526
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/186 (22%), Positives = 84/186 (45%), Gaps = 5/186 (2%)
Query: 169 RELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKR 228
++LY+ + + F ++ + L +NRI+ ++ AF + + L N I++
Sbjct: 411 KKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEK 470
Query: 229 ILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV 287
+ F GL + + IR I+P AF+ + + +L L L +L D F G +
Sbjct: 471 LTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAG-TSL 529
Query: 288 GRLSLRESDLGIIKV-GSFDGLQHVDTLEICNNKIDGIEELSLVQN--NSVRVFKLTGNH 344
RL+LR++ + V G + L + +++ N D +L + ++ + G+
Sbjct: 530 ARLNLRKNYFLYLPVAGVLEHLNAIVQIDLNENPWDCTCDLVPFKQWIETISSVSVVGDV 589
Query: 345 MLESPE 350
+ SPE
Sbjct: 590 LCRSPE 595
Score = 38.7 bits (86), Expect = 0.042
Identities = 34/133 (25%), Positives = 63/133 (47%), Gaps = 3/133 (2%)
Query: 145 RRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQ 204
++L L + + +I F L L++ + ++ V AF L N+ S+ L N I +
Sbjct: 411 KKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEK 470
Query: 205 IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAG--LE 261
+ F G ++ + N I+ I AFS + ++ + L + +RT+ AFAG L
Sbjct: 471 LTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLA 530
Query: 262 GIGVLELAFMDLP 274
+ + + F+ LP
Sbjct: 531 RLNLRKNYFLYLP 543
Score = 37.5 bits (83), Expect = 0.097
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 2/122 (1%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+ +R + +F L + L L + F+GL + RL L E+ L + + +F
Sbjct: 87 NSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRNDTFL 146
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN--HMLESPEAVVLEVENIIIRGN 364
GL+ ++ L+ N I IE + + +RV L N ML + + + ++ +RGN
Sbjct: 147 GLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAVSLTHLDLRGN 206
Query: 365 HL 366
L
Sbjct: 207 RL 208
Score = 35.9 bits (79), Expect = 0.30
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 2/109 (1%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P++ L L+ D+ L F L+ L L + + I+P AF +P L+ L++ +
Sbjct: 456 PNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNL 515
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIE-SYAFAGTNFINLISLRNNP 225
L T+ + AFA ++ + L N + + N I I L NP
Sbjct: 516 LRTLPTDAFAG-TSLARLNLRKNYFLYLPVAGVLEHLNAIVQIDLNENP 563
Score = 33.5 bits (73), Expect = 1.6
Identities = 27/121 (22%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Query: 195 IVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIE 253
+ L N + ++ + +F N I+L NN ++ I AF+GL + ++ L + +
Sbjct: 82 LYLQRNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFR 141
Query: 254 PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD--GLQHV 311
F GLE + L+ + + + F L ++ L L ++ + ++ F L H+
Sbjct: 142 NDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAVSLTHL 201
Query: 312 D 312
D
Sbjct: 202 D 202
>BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 57.2 bits (132), Expect = 1e-07
Identities = 46/192 (23%), Positives = 94/192 (48%), Gaps = 8/192 (4%)
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+T + +F GLP L+ L + +A++ S F L N++++ LT NR+ +I + F G
Sbjct: 64 ITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL 123
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMD 272
+ + L N I+ I AF L+ + +++L +R + P L + + + +
Sbjct: 124 RRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLA 183
Query: 273 L-PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
L P +L +R+ L L++ D G+ F L+++ L++ +N+++ + +
Sbjct: 184 LEPGILDTANVEALRLAGLGLQQLDEGL-----FSRLRNLHDLDVSDNQLERVPPVIRGL 238
Query: 332 NNSVRVFKLTGN 343
R+ +L GN
Sbjct: 239 RGLTRL-RLAGN 249
Score = 45.2 bits (102), Expect = 5e-04
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 5/183 (2%)
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
LY+ + +D+ +FA L + + L+ N+IA + S F ++ + L N + I
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 231 VHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GL + ++ L + IR I+P AF L+ + L+L +L +L P L R+
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPP---LRLPRLLL 173
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + L ++ G D +V+ L + + ++E + ++ ++ N + P
Sbjct: 174 LDLSHNSLLALEPGILD-TANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP 232
Query: 350 EAV 352
+
Sbjct: 233 PVI 235
Score = 44.8 bits (101), Expect = 6e-04
Identities = 48/209 (22%), Positives = 84/209 (40%), Gaps = 7/209 (3%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + L LS+ + L S F L L L L A L I FRGL RL LY+
Sbjct: 76 PGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNR 135
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
+ + AF L + + L N + + + L+ L +N + +
Sbjct: 136 IRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPR---LLLLDLSHNSLLALEPGILDTA 192
Query: 238 NDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLR-ES 295
N V + L G++ ++ F+ L + L+++ L +P GL + RL L +
Sbjct: 193 N-VEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL-ERVPPVIRGLRGLTRLRLAGNT 250
Query: 296 DLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
+ ++ GL + L++ N + +
Sbjct: 251 RIAQLRPEDLAGLAALQELDVSNLSLQAL 279
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/110 (27%), Positives = 52/110 (47%)
Query: 240 VGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGI 299
VG +GI ++ +FAGL G+ +L+L+ + SL F L + L L + L
Sbjct: 55 VGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHE 114
Query: 300 IKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
I +F GL+ ++ L + N+I I+ + + + KL N + P
Sbjct: 115 ITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALP 164
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/134 (22%), Positives = 56/134 (41%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C V C + VP + P L + + +L + +FA L L+ L L +
Sbjct: 30 CSQPQTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIA 89
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ F+ L L L + L + + F L+ + + L NRI I+ AF +
Sbjct: 90 SLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDR 149
Query: 216 INLISLRNNPIKRI 229
+ + L++N ++ +
Sbjct: 150 LLELKLQDNELRAL 163
>BC037161-1|AAH37161.1| 420|Homo sapiens trophoblast glycoprotein
protein.
Length = 420
Score = 57.2 bits (132), Expect = 1e-07
Identities = 60/219 (27%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAH---LRQLRRLALDACNLTRIR 158
V C + L VP+ L V L L+ L VL + AFA L +L L L L +R
Sbjct: 75 VKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVR 134
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINL 218
AF LP LR+L + H PLA + FAF+ + S+ + I ++ +
Sbjct: 135 AGAFEHLPSLRQLDLSHNPLADLSPFAFSG--SNASVSAPSPLVELILNHIVPPEDERQN 192
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ-AFAGLEGIGVLELAFMDLPSLL 277
S + +L A L + ++EL S P+ A L + L+L+ L SL
Sbjct: 193 RSFEGMVVAALL--AGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLT 250
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEI 316
+F L + L L ++ L ++ G+ LQ + + +
Sbjct: 251 YVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRV 289
Score = 45.6 bits (103), Expect = 4e-04
Identities = 50/191 (26%), Positives = 83/191 (43%), Gaps = 6/191 (3%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELY---IQHTPLATVDSFAFAALQNITSIVLTHN 200
+R L L L + AF P L EL + + L V + AF L ++ + L+HN
Sbjct: 93 VRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHN 152
Query: 201 RIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGL 260
+A + +AF+G+N +S + ++ IL H D Q G+ A L
Sbjct: 153 PLADLSPFAFSGSNAS--VSAPSPLVELILNHIVPP-EDERQNRSFEGMVVAALLAGRAL 209
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNK 320
+G+ LELA L D L + L L + L + SF L H+++L + +N
Sbjct: 210 QGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHLESLHLEDNA 269
Query: 321 IDGIEELSLVQ 331
+ + +L +
Sbjct: 270 LKVLHNGTLAE 280
>AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein.
Length = 673
Score = 57.2 bits (132), Expect = 1e-07
Identities = 46/192 (23%), Positives = 94/192 (48%), Gaps = 8/192 (4%)
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+T + +F GLP L+ L + +A++ S F L N++++ LT NR+ +I + F G
Sbjct: 64 ITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL 123
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMD 272
+ + L N I+ I AF L+ + +++L +R + P L + + + +
Sbjct: 124 RRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLA 183
Query: 273 L-PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
L P +L +R+ L L++ D G+ F L+++ L++ +N+++ + +
Sbjct: 184 LEPGILDTANVEALRLAGLGLQQLDEGL-----FSRLRNLHDLDVSDNQLERVPPVIRGL 238
Query: 332 NNSVRVFKLTGN 343
R+ +L GN
Sbjct: 239 RGLTRL-RLAGN 249
Score = 45.2 bits (102), Expect = 5e-04
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 5/183 (2%)
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
LY+ + +D+ +FA L + + L+ N+IA + S F ++ + L N + I
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 231 VHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GL + ++ L + IR I+P AF L+ + L+L +L +L P L R+
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPP---LRLPRLLL 173
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + L ++ G D +V+ L + + ++E + ++ ++ N + P
Sbjct: 174 LDLSHNSLLALEPGILD-TANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP 232
Query: 350 EAV 352
+
Sbjct: 233 PVI 235
Score = 44.8 bits (101), Expect = 6e-04
Identities = 48/209 (22%), Positives = 84/209 (40%), Gaps = 7/209 (3%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + L LS+ + L S F L L L L A L I FRGL RL LY+
Sbjct: 76 PGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNR 135
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
+ + AF L + + L N + + + L+ L +N + +
Sbjct: 136 IRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPR---LLLLDLSHNSLLALEPGILDTA 192
Query: 238 NDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLR-ES 295
N V + L G++ ++ F+ L + L+++ L +P GL + RL L +
Sbjct: 193 N-VEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL-ERVPPVIRGLRGLTRLRLAGNT 250
Query: 296 DLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
+ ++ GL + L++ N + +
Sbjct: 251 RIAQLRPEDLAGLAALQELDVSNLSLQAL 279
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/110 (27%), Positives = 52/110 (47%)
Query: 240 VGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGI 299
VG +GI ++ +FAGL G+ +L+L+ + SL F L + L L + L
Sbjct: 55 VGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHE 114
Query: 300 IKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
I +F GL+ ++ L + N+I I+ + + + KL N + P
Sbjct: 115 ITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALP 164
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/134 (22%), Positives = 56/134 (41%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C V C + VP + P L + + +L + +FA L L+ L L +
Sbjct: 30 CSQPQTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIA 89
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ F+ L L L + L + + F L+ + + L NRI I+ AF +
Sbjct: 90 SLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDR 149
Query: 216 INLISLRNNPIKRI 229
+ + L++N ++ +
Sbjct: 150 LLELKLQDNELRAL 163
>AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 57.2 bits (132), Expect = 1e-07
Identities = 46/192 (23%), Positives = 94/192 (48%), Gaps = 8/192 (4%)
Query: 154 LTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGT 213
+T + +F GLP L+ L + +A++ S F L N++++ LT NR+ +I + F G
Sbjct: 64 ITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL 123
Query: 214 NFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMD 272
+ + L N I+ I AF L+ + +++L +R + P L + + + +
Sbjct: 124 RRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLA 183
Query: 273 L-PSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQ 331
L P +L +R+ L L++ D G+ F L+++ L++ +N+++ + +
Sbjct: 184 LEPGILDTANVEALRLAGLGLQQLDEGL-----FSRLRNLHDLDVSDNQLERVPPVIRGL 238
Query: 332 NNSVRVFKLTGN 343
R+ +L GN
Sbjct: 239 RGLTRL-RLAGN 249
Score = 45.2 bits (102), Expect = 5e-04
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 5/183 (2%)
Query: 171 LYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRIL 230
LY+ + +D+ +FA L + + L+ N+IA + S F ++ + L N + I
Sbjct: 57 LYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEIT 116
Query: 231 VHAFSGLNDVGQIEL-PSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGR 289
F GL + ++ L + IR I+P AF L+ + L+L +L +L P L R+
Sbjct: 117 NETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPP---LRLPRLLL 173
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + L ++ G D +V+ L + + ++E + ++ ++ N + P
Sbjct: 174 LDLSHNSLLALEPGILD-TANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP 232
Query: 350 EAV 352
+
Sbjct: 233 PVI 235
Score = 44.8 bits (101), Expect = 6e-04
Identities = 48/209 (22%), Positives = 84/209 (40%), Gaps = 7/209 (3%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P + L LS+ + L S F L L L L A L I FRGL RL LY+
Sbjct: 76 PGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNR 135
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGL 237
+ + AF L + + L N + + + L+ L +N + +
Sbjct: 136 IRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPR---LLLLDLSHNSLLALEPGILDTA 192
Query: 238 NDVGQIELPS-GIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLR-ES 295
N V + L G++ ++ F+ L + L+++ L +P GL + RL L +
Sbjct: 193 N-VEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL-ERVPPVIRGLRGLTRLRLAGNT 250
Query: 296 DLGIIKVGSFDGLQHVDTLEICNNKIDGI 324
+ ++ GL + L++ N + +
Sbjct: 251 RIAQLRPEDLAGLAALQELDVSNLSLQAL 279
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/110 (27%), Positives = 52/110 (47%)
Query: 240 VGQIELPSGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGI 299
VG +GI ++ +FAGL G+ +L+L+ + SL F L + L L + L
Sbjct: 55 VGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHE 114
Query: 300 IKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
I +F GL+ ++ L + N+I I+ + + + KL N + P
Sbjct: 115 ITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALP 164
Score = 40.7 bits (91), Expect = 0.010
Identities = 30/134 (22%), Positives = 56/134 (41%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C V C + VP + P L + + +L + +FA L L+ L L +
Sbjct: 30 CSQPQTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIA 89
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
+ F+ L L L + L + + F L+ + + L NRI I+ AF +
Sbjct: 90 SLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDR 149
Query: 216 INLISLRNNPIKRI 229
+ + L++N ++ +
Sbjct: 150 LLELKLQDNELRAL 163
>AL121977-2|CAI21546.1| 420|Homo sapiens trophoblast glycoprotein
protein.
Length = 420
Score = 57.2 bits (132), Expect = 1e-07
Identities = 60/219 (27%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAH---LRQLRRLALDACNLTRIR 158
V C + L VP+ L V L L+ L VL + AFA L +L L L L +R
Sbjct: 75 VKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVR 134
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINL 218
AF LP LR+L + H PLA + FAF+ + S+ + I ++ +
Sbjct: 135 AGAFEHLPSLRQLDLSHNPLADLSPFAFSG--SNASVSAPSPLVELILNHIVPPEDERQN 192
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ-AFAGLEGIGVLELAFMDLPSLL 277
S + +L A L + ++EL S P+ A L + L+L+ L SL
Sbjct: 193 RSFEGMVVAALL--AGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLT 250
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEI 316
+F L + L L ++ L ++ G+ LQ + + +
Sbjct: 251 YVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRV 289
Score = 45.6 bits (103), Expect = 4e-04
Identities = 50/191 (26%), Positives = 83/191 (43%), Gaps = 6/191 (3%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELY---IQHTPLATVDSFAFAALQNITSIVLTHN 200
+R L L L + AF P L EL + + L V + AF L ++ + L+HN
Sbjct: 93 VRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHN 152
Query: 201 RIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGL 260
+A + +AF+G+N +S + ++ IL H D Q G+ A L
Sbjct: 153 PLADLSPFAFSGSNAS--VSAPSPLVELILNHIVPP-EDERQNRSFEGMVVAALLAGRAL 209
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNK 320
+G+ LELA L D L + L L + L + SF L H+++L + +N
Sbjct: 210 QGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHLESLHLEDNA 269
Query: 321 IDGIEELSLVQ 331
+ + +L +
Sbjct: 270 LKVLHNGTLAE 280
>AJ012159-1|CAA09930.1| 420|Homo sapiens 5T4 oncofetal trophoblast
glycoprotein protein.
Length = 420
Score = 57.2 bits (132), Expect = 1e-07
Identities = 60/219 (27%), Positives = 95/219 (43%), Gaps = 8/219 (3%)
Query: 102 VVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAH---LRQLRRLALDACNLTRIR 158
V C + L VP+ L V L L+ L VL + AFA L +L L L L +R
Sbjct: 75 VKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVR 134
Query: 159 PFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINL 218
AF LP LR+L + H PLA + FAF+ + S+ + I ++ +
Sbjct: 135 AGAFEHLPSLRQLDLSHNPLADLSPFAFSG--SNASVSAPSPLVELILNHIVPPEDERQN 192
Query: 219 ISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQ-AFAGLEGIGVLELAFMDLPSLL 277
S + +L A L + ++EL S P+ A L + L+L+ L SL
Sbjct: 193 RSFEGMVVAALL--AGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLT 250
Query: 278 PDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEI 316
+F L + L L ++ L ++ G+ LQ + + +
Sbjct: 251 YVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRV 289
Score = 45.6 bits (103), Expect = 4e-04
Identities = 50/191 (26%), Positives = 83/191 (43%), Gaps = 6/191 (3%)
Query: 144 LRRLALDACNLTRIRPFAFRGLPRLRELY---IQHTPLATVDSFAFAALQNITSIVLTHN 200
+R L L L + AF P L EL + + L V + AF L ++ + L+HN
Sbjct: 93 VRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHN 152
Query: 201 RIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTIEPQAFAGL 260
+A + +AF+G+N +S + ++ IL H D Q G+ A L
Sbjct: 153 PLADLSPFAFSGSNAS--VSAPSPLVELILNHIVPP-EDERQNRSFEGMVVAALLAGRAL 209
Query: 261 EGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNK 320
+G+ LELA L D L + L L + L + SF L H+++L + +N
Sbjct: 210 QGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHLESLHLEDNA 269
Query: 321 IDGIEELSLVQ 331
+ + +L +
Sbjct: 270 LKVLHNGTLAE 280
>AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein.
Length = 988
Score = 57.2 bits (132), Expect = 1e-07
Identities = 39/132 (29%), Positives = 67/132 (50%), Gaps = 10/132 (7%)
Query: 119 SVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPL 178
S+ L L + ++ AF +L L+ L L+ ++ ++ P FRGL L LY + +
Sbjct: 444 SLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEFNVI 503
Query: 179 ATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNN-----PIKRILVHA 233
+ AF+ + N+ + L +N + + + AFAGT+ L +LR N P+ +L H
Sbjct: 504 REIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLARL-NLRKNYFLYLPVAGVLEH- 561
Query: 234 FSGLNDVGQIEL 245
LN + QI+L
Sbjct: 562 ---LNAIVQIDL 570
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/117 (27%), Positives = 57/117 (48%)
Query: 122 QLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATV 181
+L L R +R L +++F HL + L L I+ AF GL L+ LY+ L
Sbjct: 92 KLYLQRNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVF 151
Query: 182 DSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLN 238
+ F L+++ + +N I +IES AF + + ++ L +N I + + F ++
Sbjct: 152 RNDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAVS 208
Score = 43.6 bits (98), Expect = 0.001
Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
Query: 131 RVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQ 190
++ RSD F + L L L ++ ++ AF LP L+ L++ + + F LQ
Sbjct: 433 KIYRSD-FWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQ 491
Query: 191 NITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSG 236
++ + N I +I+ AF+ + L+ L NN ++ + AF+G
Sbjct: 492 SLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAG 537
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/186 (22%), Positives = 84/186 (45%), Gaps = 5/186 (2%)
Query: 169 RELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNFINLISLRNNPIKR 228
++LY+ + + F ++ + L +NRI+ ++ AF + + L N I++
Sbjct: 422 KKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEK 481
Query: 229 ILVHAFSGLNDVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRV 287
+ F GL + + IR I+P AF+ + + +L L L +L D F G +
Sbjct: 482 LTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAG-TSL 540
Query: 288 GRLSLRESDLGIIKV-GSFDGLQHVDTLEICNNKIDGIEELSLVQN--NSVRVFKLTGNH 344
RL+LR++ + V G + L + +++ N D +L + ++ + G+
Sbjct: 541 ARLNLRKNYFLYLPVAGVLEHLNAIVQIDLNENPWDCTCDLVPFKQWIETISSVSVVGDV 600
Query: 345 MLESPE 350
+ SPE
Sbjct: 601 LCRSPE 606
Score = 38.7 bits (86), Expect = 0.042
Identities = 34/133 (25%), Positives = 63/133 (47%), Gaps = 3/133 (2%)
Query: 145 RRLALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQ 204
++L L + + +I F L L++ + ++ V AF L N+ S+ L N I +
Sbjct: 422 KKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEK 481
Query: 205 IESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIELPSG-IRTIEPQAFAG--LE 261
+ F G ++ + N I+ I AFS + ++ + L + +RT+ AFAG L
Sbjct: 482 LTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLA 541
Query: 262 GIGVLELAFMDLP 274
+ + + F+ LP
Sbjct: 542 RLNLRKNYFLYLP 554
Score = 37.5 bits (83), Expect = 0.097
Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 2/122 (1%)
Query: 247 SGIRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD 306
+ +R + +F L + L L + F+GL + RL L E+ L + + +F
Sbjct: 98 NSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRNDTFL 157
Query: 307 GLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN--HMLESPEAVVLEVENIIIRGN 364
GL+ ++ L+ N I IE + + +RV L N ML + + + ++ +RGN
Sbjct: 158 GLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAVSLTHLDLRGN 217
Query: 365 HL 366
L
Sbjct: 218 RL 219
Score = 35.9 bits (79), Expect = 0.30
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 2/109 (1%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
P++ L L+ D+ L F L+ L L + + I+P AF +P L+ L++ +
Sbjct: 467 PNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNL 526
Query: 178 LATVDSFAFAALQNITSIVLTHNRIAQIE-SYAFAGTNFINLISLRNNP 225
L T+ + AFA ++ + L N + + N I I L NP
Sbjct: 527 LRTLPTDAFAG-TSLARLNLRKNYFLYLPVAGVLEHLNAIVQIDLNENP 574
Score = 33.5 bits (73), Expect = 1.6
Identities = 27/121 (22%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Query: 195 IVLTHNRIAQIESYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL-PSGIRTIE 253
+ L N + ++ + +F N I+L NN ++ I AF+GL + ++ L + +
Sbjct: 93 LYLQRNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFR 152
Query: 254 PQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDLGIIKVGSFD--GLQHV 311
F GLE + L+ + + + F L ++ L L ++ + ++ F L H+
Sbjct: 153 NDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAVSLTHL 212
Query: 312 D 312
D
Sbjct: 213 D 213
>BC101761-1|AAI01762.1| 545|Homo sapiens leucine-rich repeat LGI
family, member 2 protein.
Length = 545
Score = 56.8 bits (131), Expect = 1e-07
Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 3/129 (2%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C +S ++C ++ VP + ++ LSL ++ F+HL L+ L L++ + T
Sbjct: 42 CTKES-IICVGSSW--VPRIVPGDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFT 98
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
IR AF GL L L+I+ + T+ AF L+++T + L +N I + F+ +
Sbjct: 99 IIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDS 158
Query: 216 INLISLRNN 224
+ + LR N
Sbjct: 159 LIELDLRGN 167
Score = 48.0 bits (109), Expect = 7e-05
Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 3/126 (2%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + II+ +F GL H++ L I NKI+ I + + L NH+ P
Sbjct: 90 LLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALP 149
Query: 350 EAVVLEVENII---IRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKVRGRSLASAT 406
V +++++I +RGN C+C L ++ + CI P + + + L T
Sbjct: 150 RDVFSDLDSLIELDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNDVT 209
Query: 407 SGSAGC 412
S C
Sbjct: 210 SFDYEC 215
Score = 43.2 bits (97), Expect = 0.002
Identities = 28/99 (28%), Positives = 47/99 (47%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L+L + I+ F LP L+ L + + AFA L ++ + + N+I I
Sbjct: 66 LSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETIS 125
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
AF G + +SL NN IK + FS L+ + +++L
Sbjct: 126 RNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDL 164
Score = 38.7 bits (86), Expect = 0.042
Identities = 24/84 (28%), Positives = 40/84 (47%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
PS+ L L+ ++R DAFA L L L ++ + I AFRGL L L + +
Sbjct: 85 PSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNH 144
Query: 178 LATVDSFAFAALQNITSIVLTHNR 201
+ + F+ L ++ + L N+
Sbjct: 145 IKALPRDVFSDLDSLIELDLRGNK 168
Score = 33.1 bits (72), Expect = 2.1
Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 1/106 (0%)
Query: 239 DVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
D+ + L +G I+ + F+ L + +L L + D F GL + L + + +
Sbjct: 62 DISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
I +F GL+ + L + NN I + +S+ L GN
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGN 167
Score = 32.3 bits (70), Expect = 3.6
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 1/108 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTI-EPQAFAGLEGIGVLELAFMDLP 274
I+ +SL N I FS L + + L S TI AFAGL + L + +
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
++ + F GL + LSL + + + F L + L++ NK +
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
>BC101759-1|AAI01760.1| 545|Homo sapiens leucine-rich repeat LGI
family, member 2 protein.
Length = 545
Score = 56.8 bits (131), Expect = 1e-07
Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 3/129 (2%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C +S ++C ++ VP + ++ LSL ++ F+HL L+ L L++ + T
Sbjct: 42 CTKES-IICVGSSW--VPRIVPGDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFT 98
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
IR AF GL L L+I+ + T+ AF L+++T + L +N I + F+ +
Sbjct: 99 IIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDS 158
Query: 216 INLISLRNN 224
+ + LR N
Sbjct: 159 LIELDLRGN 167
Score = 48.0 bits (109), Expect = 7e-05
Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 3/126 (2%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + II+ +F GL H++ L I NKI+ I + + L NH+ P
Sbjct: 90 LLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALP 149
Query: 350 EAVVLEVENII---IRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKVRGRSLASAT 406
V +++++I +RGN C+C L ++ + CI P + + + L T
Sbjct: 150 RDVFSDLDSLIELDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNDVT 209
Query: 407 SGSAGC 412
S C
Sbjct: 210 SFDYEC 215
Score = 43.2 bits (97), Expect = 0.002
Identities = 28/99 (28%), Positives = 47/99 (47%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L+L + I+ F LP L+ L + + AFA L ++ + + N+I I
Sbjct: 66 LSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETIS 125
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
AF G + +SL NN IK + FS L+ + +++L
Sbjct: 126 RNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDL 164
Score = 38.7 bits (86), Expect = 0.042
Identities = 24/84 (28%), Positives = 40/84 (47%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
PS+ L L+ ++R DAFA L L L ++ + I AFRGL L L + +
Sbjct: 85 PSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNH 144
Query: 178 LATVDSFAFAALQNITSIVLTHNR 201
+ + F+ L ++ + L N+
Sbjct: 145 IKALPRDVFSDLDSLIELDLRGNK 168
Score = 33.1 bits (72), Expect = 2.1
Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 1/106 (0%)
Query: 239 DVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
D+ + L +G I+ + F+ L + +L L + D F GL + L + + +
Sbjct: 62 DISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
I +F GL+ + L + NN I + +S+ L GN
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGN 167
Score = 32.3 bits (70), Expect = 3.6
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 1/108 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTI-EPQAFAGLEGIGVLELAFMDLP 274
I+ +SL N I FS L + + L S TI AFAGL + L + +
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
++ + F GL + LSL + + + F L + L++ NK +
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
>AJ487958-1|CAD32305.1| 545|Homo sapiens LGI1-like protein 2
protein.
Length = 545
Score = 56.8 bits (131), Expect = 1e-07
Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 3/129 (2%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C +S ++C ++ VP + ++ LSL ++ F+HL L+ L L++ + T
Sbjct: 42 CTKES-IICVGSSW--VPRIVPGDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFT 98
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
IR AF GL L L+I+ + T+ AF L+++T + L +N I + F+ +
Sbjct: 99 IIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDS 158
Query: 216 INLISLRNN 224
+ + LR N
Sbjct: 159 LIELDLRGN 167
Score = 48.0 bits (109), Expect = 7e-05
Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 3/126 (2%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + II+ +F GL H++ L I NKI+ I + + L NH+ P
Sbjct: 90 LLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALP 149
Query: 350 EAVVLEVENII---IRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKVRGRSLASAT 406
V +++++I +RGN C+C L ++ + CI P + + + L T
Sbjct: 150 RDVFSDLDSLIELDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNDVT 209
Query: 407 SGSAGC 412
S C
Sbjct: 210 SFDYEC 215
Score = 43.2 bits (97), Expect = 0.002
Identities = 28/99 (28%), Positives = 47/99 (47%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L+L + I+ F LP L+ L + + AFA L ++ + + N+I I
Sbjct: 66 LSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETIS 125
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
AF G + +SL NN IK + FS L+ + +++L
Sbjct: 126 RNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDL 164
Score = 38.7 bits (86), Expect = 0.042
Identities = 24/84 (28%), Positives = 40/84 (47%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
PS+ L L+ ++R DAFA L L L ++ + I AFRGL L L + +
Sbjct: 85 PSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNH 144
Query: 178 LATVDSFAFAALQNITSIVLTHNR 201
+ + F+ L ++ + L N+
Sbjct: 145 IKALPRDVFSDLDSLIELDLRGNK 168
Score = 33.1 bits (72), Expect = 2.1
Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 1/106 (0%)
Query: 239 DVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
D+ + L +G I+ + F+ L + +L L + D F GL + L + + +
Sbjct: 62 DISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
I +F GL+ + L + NN I + +S+ L GN
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGN 167
Score = 32.3 bits (70), Expect = 3.6
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 1/108 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTI-EPQAFAGLEGIGVLELAFMDLP 274
I+ +SL N I FS L + + L S TI AFAGL + L + +
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
++ + F GL + LSL + + + F L + L++ NK +
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
>AJ487516-1|CAD31784.1| 545|Homo sapiens leucine-rich glioma
inactivated protein 2 protein.
Length = 545
Score = 56.8 bits (131), Expect = 1e-07
Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 3/129 (2%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C +S ++C ++ VP + ++ LSL ++ F+HL L+ L L++ + T
Sbjct: 42 CTKES-IICVGSSW--VPRIVPGDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFT 98
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
IR AF GL L L+I+ + T+ AF L+++T + L +N I + F+ +
Sbjct: 99 IIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDS 158
Query: 216 INLISLRNN 224
+ + LR N
Sbjct: 159 LIELDLRGN 167
Score = 48.0 bits (109), Expect = 7e-05
Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 3/126 (2%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + II+ +F GL H++ L I NKI+ I + + L NH+ P
Sbjct: 90 LLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALP 149
Query: 350 EAVVLEVENII---IRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKVRGRSLASAT 406
V +++++I +RGN C+C L ++ + CI P + + + L T
Sbjct: 150 RDVFSDLDSLIELDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNDVT 209
Query: 407 SGSAGC 412
S C
Sbjct: 210 SFDYEC 215
Score = 43.2 bits (97), Expect = 0.002
Identities = 28/99 (28%), Positives = 47/99 (47%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L+L + I+ F LP L+ L + + AFA L ++ + + N+I I
Sbjct: 66 LSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETIS 125
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
AF G + +SL NN IK + FS L+ + +++L
Sbjct: 126 RNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDL 164
Score = 38.7 bits (86), Expect = 0.042
Identities = 24/84 (28%), Positives = 40/84 (47%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
PS+ L L+ ++R DAFA L L L ++ + I AFRGL L L + +
Sbjct: 85 PSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNH 144
Query: 178 LATVDSFAFAALQNITSIVLTHNR 201
+ + F+ L ++ + L N+
Sbjct: 145 IKALPRDVFSDLDSLIELDLRGNK 168
Score = 33.1 bits (72), Expect = 2.1
Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 1/106 (0%)
Query: 239 DVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
D+ + L +G I+ + F+ L + +L L + D F GL + L + + +
Sbjct: 62 DISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
I +F GL+ + L + NN I + +S+ L GN
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGN 167
Score = 32.3 bits (70), Expect = 3.6
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 1/108 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTI-EPQAFAGLEGIGVLELAFMDLP 274
I+ +SL N I FS L + + L S TI AFAGL + L + +
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
++ + F GL + LSL + + + F L + L++ NK +
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
>AF467955-1|AAM49553.1| 545|Homo sapiens LGI2 protein.
Length = 545
Score = 56.8 bits (131), Expect = 1e-07
Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 3/129 (2%)
Query: 96 CLSQSQVVCNSAALRGVPSGLSPSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLT 155
C +S ++C ++ VP + ++ LSL ++ F+HL L+ L L++ + T
Sbjct: 42 CTKES-IICVGSSW--VPRIVPGDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFT 98
Query: 156 RIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIESYAFAGTNF 215
IR AF GL L L+I+ + T+ AF L+++T + L +N I + F+ +
Sbjct: 99 IIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDS 158
Query: 216 INLISLRNN 224
+ + LR N
Sbjct: 159 LIELDLRGN 167
Score = 48.0 bits (109), Expect = 7e-05
Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 3/126 (2%)
Query: 290 LSLRESDLGIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGNHMLESP 349
L L + II+ +F GL H++ L I NKI+ I + + L NH+ P
Sbjct: 90 LLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALP 149
Query: 350 EAVVLEVENII---IRGNHLPCECGRDPFTNPLALSQDFAEENYCISPLKVRGRSLASAT 406
V +++++I +RGN C+C L ++ + CI P + + + L T
Sbjct: 150 RDVFSDLDSLIELDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNDVT 209
Query: 407 SGSAGC 412
S C
Sbjct: 210 SFDYEC 215
Score = 43.2 bits (97), Expect = 0.002
Identities = 28/99 (28%), Positives = 47/99 (47%)
Query: 147 LALDACNLTRIRPFAFRGLPRLRELYIQHTPLATVDSFAFAALQNITSIVLTHNRIAQIE 206
L+L + I+ F LP L+ L + + AFA L ++ + + N+I I
Sbjct: 66 LSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETIS 125
Query: 207 SYAFAGTNFINLISLRNNPIKRILVHAFSGLNDVGQIEL 245
AF G + +SL NN IK + FS L+ + +++L
Sbjct: 126 RNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDL 164
Score = 38.7 bits (86), Expect = 0.042
Identities = 24/84 (28%), Positives = 40/84 (47%)
Query: 118 PSVTQLSLSRADLRVLRSDAFAHLRQLRRLALDACNLTRIRPFAFRGLPRLRELYIQHTP 177
PS+ L L+ ++R DAFA L L L ++ + I AFRGL L L + +
Sbjct: 85 PSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNH 144
Query: 178 LATVDSFAFAALQNITSIVLTHNR 201
+ + F+ L ++ + L N+
Sbjct: 145 IKALPRDVFSDLDSLIELDLRGNK 168
Score = 33.1 bits (72), Expect = 2.1
Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 1/106 (0%)
Query: 239 DVGQIELPSG-IRTIEPQAFAGLEGIGVLELAFMDLPSLLPDTFHGLIRVGRLSLRESDL 297
D+ + L +G I+ + F+ L + +L L + D F GL + L + + +
Sbjct: 62 DISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKI 121
Query: 298 GIIKVGSFDGLQHVDTLEICNNKIDGIEELSLVQNNSVRVFKLTGN 343
I +F GL+ + L + NN I + +S+ L GN
Sbjct: 122 ETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGN 167
Score = 32.3 bits (70), Expect = 3.6
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 1/108 (0%)
Query: 216 INLISLRNNPIKRILVHAFSGLNDVGQIELPSGIRTI-EPQAFAGLEGIGVLELAFMDLP 274
I+ +SL N I FS L + + L S TI AFAGL + L + +
Sbjct: 63 ISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIE 122
Query: 275 SLLPDTFHGLIRVGRLSLRESDLGIIKVGSFDGLQHVDTLEICNNKID 322
++ + F GL + LSL + + + F L + L++ NK +
Sbjct: 123 TISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFE 170
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.324 0.138 0.407
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 56,161,697
Number of Sequences: 224733
Number of extensions: 2087150
Number of successful extensions: 9188
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 435
Number of HSP's successfully gapped in prelim test: 147
Number of HSP's that attempted gapping in prelim test: 4391
Number of HSP's gapped (non-prelim): 2694
length of query: 454
length of database: 73,234,838
effective HSP length: 92
effective length of query: 362
effective length of database: 52,559,402
effective search space: 19026503524
effective search space used: 19026503524
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.5 bits)
S2: 67 (31.1 bits)
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