BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000958-TA|BGIBMGA000958-PA|IPR002524|Cation efflux protein, IPR009061|Putative DNA binding (436 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_A1Z935 Cluster: CG8632-PB, isoform B; n=9; Endopterygot... 549 e-155 UniRef50_Q6PML9 Cluster: Zinc transporter 9; n=33; Eumetazoa|Rep... 502 e-140 UniRef50_UPI0000E4758C Cluster: PREDICTED: similar to Solute car... 477 e-133 UniRef50_Q3V5J4 Cluster: Putative uncharacterized protein; n=3; ... 284 3e-75 UniRef50_A7Q458 Cluster: Chromosome chr9 scaffold_49, whole geno... 264 2e-69 UniRef50_Q8H1G3 Cluster: Metal tolerance protein C4; n=3; Magnol... 255 2e-66 UniRef50_Q01GU4 Cluster: Membrane protein HUEL; n=2; Ostreococcu... 238 2e-61 UniRef50_Q4RTG8 Cluster: Chromosome 1 SCAF14998, whole genome sh... 234 4e-60 UniRef50_A6G134 Cluster: Predicted Co/Zn/Cd cation transporter; ... 220 7e-56 UniRef50_A6C709 Cluster: Cation efflux protein; n=1; Planctomyce... 200 4e-50 UniRef50_A0M1Q8 Cluster: CDF family cation efflux protein; n=1; ... 176 1e-42 UniRef50_Q1Q491 Cluster: Putative uncharacterized protein; n=1; ... 163 1e-38 UniRef50_Q2SF35 Cluster: Predicted Co/Zn/Cd cation transporters;... 156 9e-37 UniRef50_Q3JA92 Cluster: Cation efflux protein; n=4; Bacteria|Re... 156 1e-36 UniRef50_Q1QCT7 Cluster: Cation diffusion facilitator family tra... 156 1e-36 UniRef50_Q0F0R3 Cluster: Predicted Co/Zn/Cd cation transporters;... 150 8e-35 UniRef50_Q98D48 Cluster: Mll4860 protein; n=10; Proteobacteria|R... 146 1e-33 UniRef50_A6EC28 Cluster: Predicted Co/Zn/Cd cation transporter; ... 145 2e-33 UniRef50_A3IUW6 Cluster: Predicted Co/Zn/Cd cation transporters;... 144 5e-33 UniRef50_A1SQA1 Cluster: Cation diffusion facilitator family tra... 144 5e-33 UniRef50_Q0BR38 Cluster: Cobalt-zinc-cadmium resistance protein ... 142 2e-32 UniRef50_Q9L081 Cluster: Putative membrane transport protein; n=... 141 4e-32 UniRef50_A5V609 Cluster: Cation diffusion facilitator family tra... 140 7e-32 UniRef50_Q6A747 Cluster: Cation transport protein; n=1; Propioni... 134 6e-30 UniRef50_A6W6F7 Cluster: Cation diffusion facilitator family tra... 133 1e-29 UniRef50_Q6AHA9 Cluster: Cation transporter; n=1; Leifsonia xyli... 132 2e-29 UniRef50_A0GH18 Cluster: Cation diffusion facilitator family tra... 129 2e-28 UniRef50_A5P265 Cluster: Cation diffusion facilitator family tra... 124 3e-27 UniRef50_A7D914 Cluster: Cation diffusion facilitator family tra... 122 2e-26 UniRef50_A2XRM0 Cluster: Putative uncharacterized protein; n=1; ... 120 1e-25 UniRef50_Q2JCE5 Cluster: Cation diffusion facilitator family tra... 118 4e-25 UniRef50_Q825J3 Cluster: Putative transport protein; n=4; Strept... 117 7e-25 UniRef50_A4J438 Cluster: Cation diffusion facilitator family tra... 116 2e-24 UniRef50_Q3IUM9 Cluster: Transporter 37; n=1; Natronomonas phara... 115 3e-24 UniRef50_Q5UZ15 Cluster: Cation efflux protein; n=1; Haloarcula ... 112 2e-23 UniRef50_Q5FU46 Cluster: Cation efflux system protein; n=1; Gluc... 95 4e-18 UniRef50_Q838Z8 Cluster: Cation efflux family protein; n=4; Lact... 93 2e-17 UniRef50_A1A1Q0 Cluster: Cation transporter; n=3; Bifidobacteriu... 91 7e-17 UniRef50_A5ZXZ3 Cluster: Putative uncharacterized protein; n=1; ... 83 1e-14 UniRef50_Q5UX98 Cluster: Cation efflux system protein; n=3; Halo... 81 7e-14 UniRef50_A5FSC2 Cluster: Cation diffusion facilitator family tra... 80 1e-13 UniRef50_Q92AW3 Cluster: Lin1805 protein; n=17; Bacillales|Rep: ... 79 2e-13 UniRef50_A0DMX0 Cluster: Chromosome undetermined scaffold_57, wh... 76 2e-12 UniRef50_UPI00006CBFC4 Cluster: cation efflux family protein; n=... 74 6e-12 UniRef50_A0KRS9 Cluster: Cation diffusion facilitator family tra... 72 3e-11 UniRef50_Q3IQA7 Cluster: Transporter 38; n=1; Natronomonas phara... 66 2e-09 UniRef50_A6NR09 Cluster: Putative uncharacterized protein; n=1; ... 64 7e-09 UniRef50_A6DS63 Cluster: MMT1 protein; n=1; Lentisphaera araneos... 64 7e-09 UniRef50_O28143 Cluster: Conserved hypothetical transmembrane pr... 63 1e-08 UniRef50_A1THH9 Cluster: Cation diffusion facilitator family tra... 62 2e-08 UniRef50_P74068 Cluster: Uncharacterized transporter sll1263; n=... 62 3e-08 UniRef50_A4EAI9 Cluster: Putative uncharacterized protein; n=1; ... 60 9e-08 UniRef50_Q2SCG7 Cluster: Predicted Co/Zn/Cd cation transporters;... 60 1e-07 UniRef50_A6VZC2 Cluster: Cation diffusion facilitator family tra... 60 1e-07 UniRef50_A4E9J2 Cluster: Putative uncharacterized protein; n=1; ... 60 1e-07 UniRef50_Q8VLX7 Cluster: CzrB protein; n=3; Thermus thermophilus... 59 2e-07 UniRef50_A7AEG5 Cluster: Putative uncharacterized protein; n=1; ... 59 3e-07 UniRef50_Q8Y4L4 Cluster: Lmo2423 protein; n=14; Bacillales|Rep: ... 58 3e-07 UniRef50_Q6MQU1 Cluster: Cation efflux system protein; n=1; Bdel... 58 3e-07 UniRef50_A6TSV8 Cluster: Cation diffusion facilitator family tra... 58 3e-07 UniRef50_Q57891 Cluster: Uncharacterized transporter MJ0449; n=4... 58 3e-07 UniRef50_Q2BDX4 Cluster: Putative uncharacterized protein; n=2; ... 58 5e-07 UniRef50_A4J2G0 Cluster: Cation diffusion facilitator family tra... 58 5e-07 UniRef50_Q97K27 Cluster: Cation efflux system protein; n=1; Clos... 58 6e-07 UniRef50_Q8RDD5 Cluster: Predicted Co/Zn/Cd cation transporters;... 58 6e-07 UniRef50_A7CAR0 Cluster: Cation diffusion facilitator family tra... 57 8e-07 UniRef50_A1AWZ0 Cluster: Cation diffusion facilitator family tra... 57 8e-07 UniRef50_A1SH46 Cluster: Cation diffusion facilitator family tra... 57 1e-06 UniRef50_A1K3F1 Cluster: Putative cobalt-zinc-cadmium resistance... 57 1e-06 UniRef50_Q97LF5 Cluster: C-terminal region cation efflux system ... 56 1e-06 UniRef50_A7GZD1 Cluster: MMT1 protein; n=1; Campylobacter curvus... 56 1e-06 UniRef50_Q0W2J0 Cluster: Predicted cation efflux protein; n=3; E... 56 1e-06 UniRef50_Q837I0 Cluster: Cation efflux family protein; n=1; Ente... 56 2e-06 UniRef50_Q6A6E4 Cluster: Predicted Co/Zn/Cd cation transporter; ... 56 2e-06 UniRef50_Q6NE50 Cluster: Magnetosome protein MamB; n=5; Magnetos... 56 2e-06 UniRef50_A1WC43 Cluster: Cation diffusion facilitator family tra... 56 2e-06 UniRef50_A0KQ43 Cluster: Cation efflux family protein; n=2; Aero... 56 2e-06 UniRef50_Q98HP4 Cluster: Mlr2775 protein; n=12; Bacteria|Rep: Ml... 55 3e-06 UniRef50_A5EV87 Cluster: Cation efflux family protein; n=1; Dich... 55 3e-06 UniRef50_A5KR43 Cluster: Putative uncharacterized protein; n=2; ... 54 6e-06 UniRef50_A0NZQ3 Cluster: Cation efflux transporter, CDF family p... 54 6e-06 UniRef50_Q83BX5 Cluster: Cation-efflux family protein; n=2; Coxi... 54 7e-06 UniRef50_A6F284 Cluster: Predicted Co/Zn/Cd cation transporter; ... 54 7e-06 UniRef50_Q4IXC3 Cluster: Cation efflux protein; n=18; Pseudomona... 54 1e-05 UniRef50_Q3E481 Cluster: Cation efflux protein; n=5; Bacteria|Re... 54 1e-05 UniRef50_Q1LHU8 Cluster: Cation diffusion facilitator family tra... 53 1e-05 UniRef50_A6PM43 Cluster: Cation diffusion facilitator family tra... 53 1e-05 UniRef50_Q65T10 Cluster: MMT1 protein; n=1; Mannheimia succinici... 53 2e-05 UniRef50_Q11X42 Cluster: Cation efflux system protein; n=8; Bact... 53 2e-05 UniRef50_A6BDG0 Cluster: Putative uncharacterized protein; n=2; ... 53 2e-05 UniRef50_A3VV32 Cluster: Cation efflux family protein; n=1; Parv... 53 2e-05 UniRef50_A1BEH5 Cluster: Cation diffusion facilitator family tra... 53 2e-05 UniRef50_Q6LZI4 Cluster: Cation efflux protein; n=11; cellular o... 53 2e-05 UniRef50_O30282 Cluster: Conserved hypothetical transmembrane pr... 53 2e-05 UniRef50_Q479I8 Cluster: Cation efflux protein; n=1; Dechloromon... 52 2e-05 UniRef50_Q83PD6 Cluster: Cation-efflux pump fieF; n=70; Gammapro... 52 2e-05 UniRef50_Q9A2C4 Cluster: Cation efflux family protein; n=4; Alph... 52 3e-05 UniRef50_Q18YB5 Cluster: Cation diffusion facilitator family tra... 52 3e-05 UniRef50_Q0BW07 Cluster: Cobalt-zinc-cadmium resistance protein ... 52 3e-05 UniRef50_A3CXT0 Cluster: Cation diffusion facilitator family tra... 52 3e-05 UniRef50_Q0KAF7 Cluster: Cobalt-zinc-cadmium resistance protein ... 52 4e-05 UniRef50_Q1EYD3 Cluster: Cation efflux protein precursor; n=1; C... 51 5e-05 UniRef50_A6ECE5 Cluster: Cation efflux protein; n=1; Pedobacter ... 51 5e-05 UniRef50_Q8PTD7 Cluster: Cobalt-zinc-cadmium resistance protein;... 51 7e-05 UniRef50_UPI0000383D2E Cluster: COG0053: Predicted Co/Zn/Cd cati... 50 9e-05 UniRef50_Q5P2F7 Cluster: Putative uncharacterized protein; n=1; ... 50 9e-05 UniRef50_P96691 Cluster: YdfM protein; n=2; Bacillus|Rep: YdfM p... 50 9e-05 UniRef50_Q0AY41 Cluster: Putative cation efflux system protein; ... 50 9e-05 UniRef50_A5Z978 Cluster: Putative uncharacterized protein; n=2; ... 50 9e-05 UniRef50_Q7NKM3 Cluster: Gll1454 protein; n=3; Bacteria|Rep: Gll... 50 1e-04 UniRef50_A3XEG4 Cluster: Cation efflux system protein; n=9; Prot... 50 1e-04 UniRef50_A5ULB6 Cluster: Cation efflux system protein; n=1; Meth... 50 1e-04 UniRef50_Q3AES4 Cluster: Cation efflux family protein; n=1; Carb... 50 2e-04 UniRef50_Q9KDH5 Cluster: Cation efflux system; n=4; Bacillaceae|... 49 2e-04 UniRef50_Q2JWZ6 Cluster: Cation transporter, cation diffusion fa... 49 2e-04 UniRef50_Q565Y9 Cluster: Predicted Co/Zn/Cd cation transporter; ... 49 2e-04 UniRef50_A3X492 Cluster: Cation efflux transporter, CDF family p... 49 2e-04 UniRef50_A7DRF6 Cluster: Cation diffusion facilitator family tra... 49 2e-04 UniRef50_Q2W8Q4 Cluster: Predicted Co/Zn/Cd cation transporters;... 49 3e-04 UniRef50_Q2W8P3 Cluster: Predicted Co/Zn/Cd cation transporters;... 49 3e-04 UniRef50_O85143 Cluster: Transport protein; n=35; Bacteria|Rep: ... 49 3e-04 UniRef50_A5FYR2 Cluster: Cation diffusion facilitator family tra... 49 3e-04 UniRef50_Q5ZTX4 Cluster: Cation efflux family protein; n=4; Legi... 48 4e-04 UniRef50_A7GZ19 Cluster: Pantothenate metabolism flavoprotein; n... 48 4e-04 UniRef50_Q3A4F2 Cluster: Putative transport system permease prot... 48 5e-04 UniRef50_Q01VH6 Cluster: Cation diffusion facilitator family tra... 48 5e-04 UniRef50_A1WYJ4 Cluster: Cation diffusion facilitator family tra... 48 5e-04 UniRef50_A1HSL0 Cluster: Cation diffusion facilitator family tra... 48 5e-04 UniRef50_Q5LTM6 Cluster: Cation efflux system protein; n=13; Alp... 48 6e-04 UniRef50_Q6QSW0 Cluster: Cation efflux facilitator; n=1; Enteroc... 48 6e-04 UniRef50_Q03ZB0 Cluster: Co/Zn/Cd efflux system component; n=1; ... 48 6e-04 UniRef50_Q8KEZ4 Cluster: Cation efflux family protein; n=6; Chlo... 47 8e-04 UniRef50_A7HL40 Cluster: Cation diffusion facilitator family tra... 47 8e-04 UniRef50_A1VH99 Cluster: Cation diffusion facilitator family tra... 47 8e-04 UniRef50_Q311T6 Cluster: Cation diffusion facilitator family tra... 47 0.001 UniRef50_A6CU38 Cluster: Cation efflux family protein; probable ... 47 0.001 UniRef50_A3CRV2 Cluster: Cation diffusion facilitator family tra... 47 0.001 UniRef50_Q9KEY7 Cluster: Cation efflux system; n=11; Bacillus|Re... 46 0.001 UniRef50_Q57BV0 Cluster: Cation efflux family protein; n=9; Rhiz... 46 0.001 UniRef50_Q2RHV4 Cluster: Cation diffusion facilitator family tra... 46 0.001 UniRef50_A3ZLV0 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002 UniRef50_A3EVG9 Cluster: Putative Co/Zn/Cd cation transporter; n... 46 0.002 UniRef50_A1TZF9 Cluster: Cation diffusion facilitator family tra... 46 0.002 UniRef50_Q5L2G4 Cluster: Cation efflux transporter; n=5; Bacilla... 46 0.003 UniRef50_Q1NQB8 Cluster: Cation efflux protein; n=2; delta prote... 46 0.003 UniRef50_A6LXL8 Cluster: Cation diffusion facilitator family tra... 46 0.003 UniRef50_A1SZS2 Cluster: Iron and zinc efflux system protein; n=... 46 0.003 UniRef50_A0AWY3 Cluster: Cation diffusion facilitator family tra... 46 0.003 UniRef50_Q5ZR77 Cluster: Putative uncharacterized protein R02F11... 46 0.003 UniRef50_Q6MCR1 Cluster: Putative cation efflux system protein; ... 45 0.003 UniRef50_Q2AI61 Cluster: Cation efflux protein; n=1; Halothermot... 45 0.003 UniRef50_A0YFC6 Cluster: Cation transporter, cation diffusion fa... 45 0.003 UniRef50_A0V364 Cluster: Cation diffusion facilitator family tra... 45 0.003 UniRef50_O27240 Cluster: Possible cation transporter; n=1; Metha... 45 0.003 UniRef50_Q1AYG3 Cluster: Cation diffusion facilitator family tra... 45 0.005 UniRef50_A1VZU0 Cluster: Cation efflux family protein; n=12; Cam... 45 0.005 UniRef50_P46348 Cluster: Uncharacterized transporter yeaB; n=19;... 45 0.005 UniRef50_Q62FW4 Cluster: Cation efflux family protein; n=48; Pro... 44 0.006 UniRef50_Q3VS68 Cluster: Cation efflux protein; n=2; Chlorobiace... 44 0.006 UniRef50_A3XRG5 Cluster: Cobalt/zinc/cadmium cation efflux pump ... 44 0.006 UniRef50_Q5D9U1 Cluster: SJCHGC08837 protein; n=1; Schistosoma j... 44 0.006 UniRef50_Q8CNH2 Cluster: CzrB protein; n=3; Staphylococcus|Rep: ... 44 0.008 UniRef50_Q5FQH9 Cluster: Cation efflux system protein; n=1; Gluc... 44 0.008 UniRef50_Q2BMX3 Cluster: Cation-efflux family protein; n=1; Nept... 44 0.008 UniRef50_A6LZH5 Cluster: Cation diffusion facilitator family tra... 44 0.008 UniRef50_A0LXC1 Cluster: CDF family cation efflux protein; n=3; ... 44 0.008 UniRef50_Q81QV5 Cluster: Cation efflux family protein; n=19; Fir... 44 0.010 UniRef50_A0LCE7 Cluster: Cation diffusion facilitator family tra... 44 0.010 UniRef50_Q5KK51 Cluster: Di-, tri-valent inorganic cation transp... 44 0.010 UniRef50_Q8TT22 Cluster: Cation efflux system protein; n=5; cell... 44 0.010 UniRef50_Q98H85 Cluster: Cation efflux system protein; n=8; Alph... 43 0.014 UniRef50_A6BIC1 Cluster: Putative uncharacterized protein; n=1; ... 43 0.014 UniRef50_Q8TT88 Cluster: Cation efflux system protein; n=4; Meth... 43 0.014 UniRef50_Q97PQ1 Cluster: Cation efflux family protein; n=41; Str... 43 0.018 UniRef50_Q7UMH1 Cluster: Cation efflux system protein; n=1; Pire... 43 0.018 UniRef50_Q74FW5 Cluster: Cation efflux family protein; n=7; Desu... 43 0.018 UniRef50_A6LME7 Cluster: Cation diffusion facilitator family tra... 43 0.018 UniRef50_A0LLF0 Cluster: Cation diffusion facilitator family tra... 43 0.018 UniRef50_A7I5F3 Cluster: Cation diffusion facilitator family tra... 43 0.018 UniRef50_Q67QQ7 Cluster: Cation efflux system protein; n=1; Symb... 42 0.024 UniRef50_A1VD81 Cluster: Cation diffusion facilitator family tra... 42 0.024 UniRef50_Q03218 Cluster: Mitochondrial metal transporter 1, mito... 42 0.024 UniRef50_A7CNS8 Cluster: Cation diffusion facilitator family tra... 42 0.032 UniRef50_A7BVM0 Cluster: Cation efflux protein; n=3; Beggiatoa s... 42 0.032 UniRef50_A4BEK1 Cluster: Predicted Co/Zn/Cd cation transporter; ... 42 0.032 UniRef50_Q97NZ2 Cluster: Cation efflux system protein; n=27; Str... 42 0.042 UniRef50_A0Y777 Cluster: Putative transport protein; n=3; Altero... 42 0.042 UniRef50_A0L9V8 Cluster: Cation diffusion facilitator family tra... 42 0.042 UniRef50_Q8ZYX3 Cluster: Cation efflux system protein, conjectur... 42 0.042 UniRef50_Q97MV4 Cluster: Predicted Co/Zn/Cd cation transporter; ... 41 0.056 UniRef50_A1IAH4 Cluster: Cation diffusion facilitator family tra... 41 0.056 UniRef50_Q8F433 Cluster: Cobalt-zinc-cadmium resistance protein ... 41 0.074 UniRef50_A5IIQ7 Cluster: Cation diffusion facilitator family tra... 41 0.074 UniRef50_A0Q5V4 Cluster: Predicted Co/Zn/Cd cation transporter; ... 41 0.074 UniRef50_A7SP61 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.074 UniRef50_Q9PF12 Cluster: Cobalt-zinc-cadmium resistance protein;... 40 0.097 UniRef50_Q6AS02 Cluster: Conserved hypothetical membrane protein... 40 0.097 UniRef50_A3ERL9 Cluster: Putative Co/Zn/Cd cation transporter; n... 40 0.097 UniRef50_A0L9W4 Cluster: Cation diffusion facilitator family tra... 40 0.097 UniRef50_A6UWS0 Cluster: Cation diffusion facilitator family tra... 40 0.097 UniRef50_Q8L725 Cluster: Metal tolerance protein C1; n=2; Arabid... 40 0.097 UniRef50_Q2PY00 Cluster: Nucleoside transporter; n=1; uncultured... 40 0.13 UniRef50_Q036T5 Cluster: Predicted Co/Zn/Cd cation transporter; ... 40 0.13 UniRef50_A6EF02 Cluster: Cation efflux system protein; n=1; Pedo... 40 0.13 UniRef50_A6CGW2 Cluster: Putative cation efflux system protein; ... 40 0.13 UniRef50_A4M6M7 Cluster: Cation diffusion facilitator family tra... 40 0.13 UniRef50_A4IN96 Cluster: Cation efflux family protein; n=3; Baci... 40 0.13 UniRef50_A3DKT1 Cluster: Cation diffusion facilitator family tra... 40 0.13 UniRef50_Q607F9 Cluster: Cation efflux family protein; n=7; Bact... 40 0.17 UniRef50_A5WCY6 Cluster: Cation diffusion facilitator family tra... 40 0.17 UniRef50_A1ZDC5 Cluster: Heavy metal efflux pump, CzcD family; n... 40 0.17 UniRef50_A3H9P4 Cluster: Cation diffusion facilitator family tra... 40 0.17 UniRef50_Q6D7E5 Cluster: Zinc transporter zitB; n=40; Enterobact... 40 0.17 UniRef50_Q12263 Cluster: Serine/threonine-protein kinase GIN4; n... 40 0.17 UniRef50_Q2NTU9 Cluster: Putative transport protein; n=1; Sodali... 39 0.22 UniRef50_O67851 Cluster: Putative uncharacterized protein; n=1; ... 39 0.22 UniRef50_A0VV15 Cluster: Cation diffusion facilitator family tra... 39 0.22 UniRef50_UPI0000499CA1 Cluster: cation diffusion facilitator fam... 39 0.30 UniRef50_Q3AYC0 Cluster: Cation efflux protein; n=13; Cyanobacte... 39 0.30 UniRef50_Q2NBG7 Cluster: Cation efflux system protein; n=3; Prot... 39 0.30 UniRef50_A5TUV7 Cluster: Possible CDF family cation diffusion fa... 39 0.30 UniRef50_A1W8N6 Cluster: Putative uncharacterized protein; n=3; ... 39 0.30 UniRef50_A1D9L0 Cluster: Di-, tri-valent inorganic cation transp... 39 0.30 UniRef50_Q8TV30 Cluster: Predicted Co/Zn/Cd cation transporter; ... 39 0.30 UniRef50_Q7MT89 Cluster: Cation efflux family protein; n=3; Bact... 38 0.39 UniRef50_Q3ZWB7 Cluster: Cation efflux family protein; n=2; Deha... 38 0.39 UniRef50_Q1IPF4 Cluster: Cation diffusion facilitator family tra... 38 0.39 UniRef50_A3UGA9 Cluster: Cation efflux protein; n=3; Proteobacte... 38 0.39 UniRef50_A4HFQ2 Cluster: Cation transporter, putative; n=3; Leis... 38 0.39 UniRef50_Q6CT16 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 38 0.39 UniRef50_Q0CAH3 Cluster: Predicted protein; n=1; Aspergillus ter... 38 0.39 UniRef50_Q8TP38 Cluster: Cation efflux system protein; n=3; Meth... 38 0.39 UniRef50_A0RND9 Cluster: Ferrous-iron efflux pump FieF; n=1; Cam... 38 0.52 UniRef50_A0IKN6 Cluster: Cation diffusion facilitator family tra... 38 0.52 UniRef50_Q7NIC0 Cluster: Gll2263 protein; n=2; Cyanobacteria|Rep... 38 0.69 UniRef50_Q749X9 Cluster: Cation efflux family protein; n=8; Delt... 38 0.69 UniRef50_Q6LGB2 Cluster: Hypothetical cation-efflux family prote... 38 0.69 UniRef50_Q2S288 Cluster: Cation efflux family protein; n=1; Sali... 38 0.69 UniRef50_Q2LWF9 Cluster: Co/Zn/Cd cation transporter; n=1; Syntr... 38 0.69 UniRef50_A5G751 Cluster: Cation diffusion facilitator family tra... 38 0.69 UniRef50_A3TRN3 Cluster: Tyrosine protein kinase:Serine/threonin... 38 0.69 UniRef50_A0LKX9 Cluster: Cation diffusion facilitator family tra... 38 0.69 UniRef50_Q4WLB1 Cluster: CDF zinc transporter (Msc2), putaitve; ... 38 0.69 UniRef50_Q2FN36 Cluster: Cation diffusion facilitator family tra... 38 0.69 UniRef50_O27915 Cluster: Cation efflux system protein; n=1; Meth... 38 0.69 UniRef50_A5UNR6 Cluster: Heavy metal cation (Co/Zn/Cd) efflux sy... 38 0.69 UniRef50_Q08970 Cluster: Mitochondrial metal transporter 2, mito... 38 0.69 UniRef50_UPI0000DAE7E5 Cluster: hypothetical protein Rgryl_01001... 37 0.91 UniRef50_Q8FU00 Cluster: Putative uncharacterized protein; n=1; ... 37 0.91 UniRef50_Q606W3 Cluster: Cation efflux family protein; n=2; Bact... 37 0.91 UniRef50_Q1GPY2 Cluster: Cation diffusion facilitator family tra... 37 0.91 UniRef50_Q11N98 Cluster: HflK protein; n=1; Mesorhizobium sp. BN... 37 0.91 UniRef50_A0QIJ5 Cluster: Cation efflux family protein; n=3; Myco... 37 0.91 UniRef50_A7I6Y5 Cluster: Cation diffusion facilitator family tra... 37 0.91 UniRef50_Q97G32 Cluster: Co/Zn/Cd efflux system component; n=1; ... 37 1.2 UniRef50_Q67K51 Cluster: Cation efflux system protein; n=1; Symb... 37 1.2 UniRef50_Q1Q6L8 Cluster: Putative uncharacterized protein; n=1; ... 37 1.2 UniRef50_A5G746 Cluster: Cation diffusion facilitator family tra... 37 1.2 UniRef50_Q20864 Cluster: Putative uncharacterized protein; n=2; ... 37 1.2 UniRef50_Q8Q0G9 Cluster: Cobalt-zinc-cadmium resistance protein;... 37 1.2 UniRef50_Q6ML10 Cluster: Cation-efflux system membrane protein; ... 36 1.6 UniRef50_Q1K0N1 Cluster: Cation diffusion facilitator family tra... 36 1.6 UniRef50_A0B5Z8 Cluster: Cation diffusion facilitator family tra... 36 1.6 UniRef50_Q6NHN1 Cluster: Cation-efflux system integral membrane ... 36 2.1 UniRef50_Q64SU7 Cluster: Cation efflux system protein; n=5; Bact... 36 2.1 UniRef50_Q07XG6 Cluster: Cation diffusion facilitator family tra... 36 2.1 UniRef50_A6E8Q8 Cluster: Mg/Co/Ni transporter; n=1; Pedobacter s... 36 2.1 UniRef50_A0RLZ7 Cluster: Cation efflux family protein; n=1; Camp... 36 2.1 UniRef50_Q5B283 Cluster: Putative uncharacterized protein; n=1; ... 36 2.1 UniRef50_UPI0000DD81FD Cluster: PREDICTED: hypothetical protein;... 36 2.8 UniRef50_A6LYH8 Cluster: Cation diffusion facilitator family tra... 36 2.8 UniRef50_A4JL20 Cluster: Filamentous haemagglutinin family outer... 36 2.8 UniRef50_A1AW34 Cluster: Acriflavin resistance protein precursor... 36 2.8 UniRef50_UPI0000D560E9 Cluster: PREDICTED: similar to CG6358-PA;... 35 3.7 UniRef50_Q7M8H2 Cluster: TRANSMEMBRANE TRANSPORT PROTEIN-Predict... 35 3.7 UniRef50_Q5HLH9 Cluster: Cation efflux family protein; n=16; Sta... 35 3.7 UniRef50_Q5FM42 Cluster: Cation efflux protein; n=5; Lactobacill... 35 3.7 UniRef50_Q0EXM1 Cluster: Outer membrane efflux protein; n=1; Mar... 35 3.7 UniRef50_A3VSL3 Cluster: Cation efflux protein; n=1; Parvularcul... 35 3.7 UniRef50_A3TMJ1 Cluster: Putative uncharacterized protein; n=1; ... 35 3.7 UniRef50_Q54T06 Cluster: Cation efflux family protein; n=1; Dict... 35 3.7 UniRef50_Q4D6N1 Cluster: Cation transporter protein, putative; n... 35 3.7 UniRef50_A7D284 Cluster: Phosphate transporter precursor; n=1; H... 35 3.7 UniRef50_A1S0U9 Cluster: Cation diffusion facilitator family tra... 35 3.7 UniRef50_P17622 Cluster: Protein ribT; n=20; Bacillaceae|Rep: Pr... 35 3.7 UniRef50_Q7NRV3 Cluster: Probable cation efflux system; n=1; Chr... 35 4.8 UniRef50_Q6N8G4 Cluster: Possible cation efflux protein precurso... 35 4.8 UniRef50_Q57CG8 Cluster: DedA family protein; n=7; Rhizobiales|R... 35 4.8 UniRef50_A6SYW0 Cluster: Cobalt-zinc-cadmium resistance protein ... 35 4.8 UniRef50_A4FNS2 Cluster: Transcriptional regulator, DeoR family;... 35 4.8 UniRef50_P93574 Cluster: 123.pep; n=4; Magnoliophyta|Rep: 123.pe... 35 4.8 UniRef50_A7PMH0 Cluster: Chromosome chr14 scaffold_21, whole gen... 35 4.8 UniRef50_A2WK96 Cluster: Putative uncharacterized protein; n=2; ... 35 4.8 UniRef50_Q5CY80 Cluster: Hypothetical low complexity protein per... 35 4.8 UniRef50_Q8TRQ7 Cluster: Cation efflux system protein; n=2; Meth... 35 4.8 UniRef50_P23025 Cluster: DNA-repair protein complementing XP-A c... 35 4.8 UniRef50_UPI00015B5386 Cluster: PREDICTED: similar to GA21362-PA... 34 6.4 UniRef50_Q62KE9 Cluster: Drug resistance transporter, EmrB/QacA ... 34 6.4 UniRef50_Q30S31 Cluster: Cation efflux protein; n=1; Thiomicrosp... 34 6.4 UniRef50_Q1NK31 Cluster: BCCT transporter precursor; n=3; cellul... 34 6.4 UniRef50_Q04D37 Cluster: Co/Zn/Cd efflux system component; n=2; ... 34 6.4 UniRef50_A7HGB0 Cluster: Transport system permease protein; n=4;... 34 6.4 UniRef50_A1SPC8 Cluster: Putative uncharacterized protein; n=1; ... 34 6.4 UniRef50_Q16R73 Cluster: DNA-repair protein complementing XP-A c... 34 6.4 UniRef50_Q0TYP1 Cluster: Putative uncharacterized protein; n=1; ... 34 6.4 UniRef50_Q64267 Cluster: DNA-repair protein complementing XP-A c... 34 6.4 UniRef50_Q97LI8 Cluster: Predicted membrane protein; n=1; Clostr... 34 8.4 UniRef50_Q7UM65 Cluster: Putative uncharacterized protein; n=1; ... 34 8.4 UniRef50_Q1YHC7 Cluster: Possible integral membrane protein; n=2... 34 8.4 UniRef50_Q0SDQ6 Cluster: Na(+):solute symporter, SSF family prot... 34 8.4 UniRef50_Q032C1 Cluster: Predicted Co/Zn/Cd cation transporter; ... 34 8.4 UniRef50_A5CV52 Cluster: Hypothetical membrane protein; n=1; Cla... 34 8.4 >UniRef50_A1Z935 Cluster: CG8632-PB, isoform B; n=9; Endopterygota|Rep: CG8632-PB, isoform B - Drosophila melanogaster (Fruit fly) Length = 660 Score = 549 bits (1356), Expect = e-155 Identities = 265/440 (60%), Positives = 333/440 (75%), Gaps = 6/440 (1%) Query: 2 RAMTEYLLKQSDLESLPKVLRRSPYESEPPITVYYRRDVEAKAIEIWGSKXXXXXXXXXX 61 RA++++LL + LESLPK+ RRSPYE EPP+TVY+RRDVEAKA+E+WGSK Sbjct: 222 RAISDFLLTAAQLESLPKIKRRSPYEQEPPMTVYWRRDVEAKAVEVWGSKENLLRERLKR 281 Query: 62 XXXXXXXXQ-----DVFTVKRRLRDYRREMSHTRSKDNVEEVGLKTRSGRVVLTAIGING 116 Q D+FTVKRRLRDYRREM +R+K ++ +SG+VV TAI IN Sbjct: 282 EVERKQYQQIYDSADLFTVKRRLRDYRREMG-SRTKVMLDNRKESEKSGQVVATAIAINA 340 Query: 117 CNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYV 176 N LFK W Y+GSHS+F+E IHSLAD +NQLILA+GI+KS Q D DHPYGY NMRYV Sbjct: 341 ANLLFKAGGWLYSGSHSMFAEVIHSLADLINQLILAFGIYKSSQSPDIDHPYGYMNMRYV 400 Query: 177 SSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIR 236 SSLISGVGIFCVG GLS YHG+ GIL P+P+ D +W Y +L G++VSEGATL+VA++ ++ Sbjct: 401 SSLISGVGIFCVGCGLSIYHGIDGILHPEPITDLFWVYCILMGSLVSEGATLVVAINELK 460 Query: 237 KGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSI 296 + A+E NMS +YV+ DP VNVVL ED AAV GV+VAA+CM +S YTG+P+ DA GS+ Sbjct: 461 RSAKENNMSFKDYVISGKDPCVNVVLCEDAAAVTGVMVAAACMGLSSYTGSPIFDAAGSL 520 Query: 297 LVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLI 356 ++G +LG VASFII +N ALVG SI E+L++INS LE D MIRAI+DVKGIDIG+ + Sbjct: 521 VIGALLGAVASFIIYTNANALVGISIASERLEKINSALEADVMIRAIYDVKGIDIGNARV 580 Query: 357 RYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDVETFLLKHGENIVDMLGGEIDR 416 RYKAE+DFDGR LTRSYL+K DL LL ++ ++D+E+FLL GENIVD++GGEIDR Sbjct: 581 RYKAELDFDGRELTRSYLDKQDLAKLLTTVRGFQKVEDLESFLLDQGENIVDLMGGEIDR 640 Query: 417 IELKLRKKFPQIRHCDLEIL 436 IE+ LR +FP+IRH DLEIL Sbjct: 641 IEMNLRTQFPEIRHVDLEIL 660 >UniRef50_Q6PML9 Cluster: Zinc transporter 9; n=33; Eumetazoa|Rep: Zinc transporter 9 - Homo sapiens (Human) Length = 568 Score = 502 bits (1237), Expect = e-140 Identities = 236/436 (54%), Positives = 316/436 (72%), Gaps = 1/436 (0%) Query: 1 MRAMTEYLLKQSDLESLPKVLRRSPYESEPPITVYYRRDVEAKAIEIWGSKXXXXXXXXX 60 +RA+ E+ LK SDLE L K+ RRSP+E TVY R DVEAK++E+WGS Sbjct: 134 VRAINEFCLKSSDLEQLRKIRRRSPHEDTESFTVYLRSDVEAKSLEVWGSPEALAREKKL 193 Query: 61 XXXXXXXXXQDVFTVKRRLRDYRREMSHTRSKDNVEEVGLKTRSGRVVLTAIGINGCNFL 120 + +F ++ LR+YR + +T+ + V K G+VV+ AI ING N Sbjct: 194 RKEAEIEYRERLFRNQKILREYRDFLGNTKPRSRTASVFFKG-PGKVVMVAICINGLNCF 252 Query: 121 FKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLI 180 FK AW YTGS S+FSE IHSL+DT NQ +LA GI KSVQ DP HPYG++NMRY+SSLI Sbjct: 253 FKFLAWIYTGSASMFSEAIHSLSDTCNQGLLALGISKSVQTPDPSHPYGFSNMRYISSLI 312 Query: 181 SGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAR 240 SGVGIF +G+GLS+YHGV G+L PQP+ WAY +L G++VSEGATL+VA++ +R+ AR Sbjct: 313 SGVGIFMMGAGLSWYHGVMGLLHPQPIESLLWAYCILAGSLVSEGATLLVAVNELRRNAR 372 Query: 241 EANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGT 300 MS Y+YVM S DPS NV+LLEDTAAV GVI+AA+CM ++ TGNPL D+LGS+ VGT Sbjct: 373 AKGMSFYKYVMESRDPSTNVILLEDTAAVLGVIIAATCMGLTSITGNPLYDSLGSLGVGT 432 Query: 301 ILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKA 360 +LG V++F+I +N AL+GRSI EQ+ + +LE D +RAIHDVK D+G +R+KA Sbjct: 433 LLGMVSAFLIYTNTEALLGRSIQPEQVQRLTELLENDPSVRAIHDVKATDLGLGKVRFKA 492 Query: 361 EVDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDVETFLLKHGENIVDMLGGEIDRIELK 420 EVDFDGR +TRSYLEK D + +L++++++ T +++ETF+LKHGENI+D LG E+DR+E + Sbjct: 493 EVDFDGRVVTRSYLEKQDFDQMLQEIQEVKTPEELETFMLKHGENIIDTLGAEVDRLEKE 552 Query: 421 LRKKFPQIRHCDLEIL 436 L+K+ P++RH DLEIL Sbjct: 553 LKKRNPEVRHVDLEIL 568 >UniRef50_UPI0000E4758C Cluster: PREDICTED: similar to Solute carrier family 30 (zinc transporter), member 9; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Solute carrier family 30 (zinc transporter), member 9 - Strongylocentrotus purpuratus Length = 602 Score = 477 bits (1177), Expect = e-133 Identities = 227/439 (51%), Positives = 311/439 (70%), Gaps = 8/439 (1%) Query: 1 MRAMTEYLLKQSDLESLPKVLRRSPYE---SEPPITVYYRRDVEAKAIEIWGSKXXXXXX 57 +RAM++YLLK SDLE L K +RRSPY+ SE + VY R DVE KAIEIWGS Sbjct: 169 VRAMSDYLLKSSDLEQLRKTVRRSPYDQESSERNMMVYLRSDVEQKAIEIWGSMDALEME 228 Query: 58 XXXXXXXXXXXXQDVFTVKRRLRDYRREMSHTRSKDNVEEVGLKTRSGRVVLTAIGINGC 117 + +F +KR +R+Y ++ E +G+VVL+AI IN Sbjct: 229 KKKRRERDAVYKEHLFLLKRAMREYDSFFGPKEPTPSIFE-----GAGQVVLSAIAINTG 283 Query: 118 NFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVS 177 NF+FKL AW Y+GS S+FSE IHSLAD NQ ILA GI++S + +HPYG++NMR++S Sbjct: 284 NFVFKLMAWLYSGSSSMFSEAIHSLADVCNQCILALGIYQSFKKPSRNHPYGFSNMRHIS 343 Query: 178 SLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRK 237 SLISGVGIFCVG+GLSFYHG+TG+L P+P+ +W+Y +LGGA+++EGATL +A++AIRK Sbjct: 344 SLISGVGIFCVGAGLSFYHGITGLLHPEPVQSLFWSYCILGGALLTEGATLSIAINAIRK 403 Query: 238 GAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSIL 297 G+ M ++YV R+ DPSVNVV +EDTAAV GVI+A SCM ++ TGNP+ D++G++ Sbjct: 404 GSTARKMKFWDYVWRARDPSVNVVFMEDTAAVIGVIIAGSCMGLTSITGNPMYDSIGALG 463 Query: 298 VGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIR 357 VGT+LG V+ F+I +N AL GRSIP +QL +++ V+E D MIR ++DVK D+G N IR Sbjct: 464 VGTLLGAVSGFLIYTNTMALTGRSIPDDQLLKLSEVMENDVMIRGVYDVKATDMGVNTIR 523 Query: 358 YKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDVETFLLKHGENIVDMLGGEIDRI 417 +KAE+D DG LTRSYL+ DL +L++++ +++VE F+LKHGE I+D LG E+DRI Sbjct: 524 FKAELDIDGAELTRSYLDTQDLEVILKEIQSFKNLEEVEYFMLKHGERIIDQLGAEVDRI 583 Query: 418 ELKLRKKFPQIRHCDLEIL 436 E ++ P++RH DLEIL Sbjct: 584 EKLIKATDPEVRHVDLEIL 602 >UniRef50_Q3V5J4 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 443 Score = 284 bits (697), Expect = 3e-75 Identities = 158/379 (41%), Positives = 224/379 (59%), Gaps = 18/379 (4%) Query: 1 MRAMTEYLLKQSDLESLP---KVLRRSPYESEPPITVYYRRDVEAKAIEIWGSKXXXXXX 57 + AM E+ LK+SDLE LP K + + + +Y +V KA+++ GS Sbjct: 71 LSAMAEFGLKESDLEDLPSHSKPVLSLTHHGKSNHQLYTLTEVYHKALKVHGS------- 123 Query: 58 XXXXXXXXXXXXQDVFTVKRRLRDYRREMSHTRSKDNVEEVGLKTRSGRVVLTAIGINGC 117 + + +++ L D R R + VE + RVV A +N C Sbjct: 124 ----TEALEAHRRPLVAMRKELTDAER----MRMRMRVETTNQHKGADRVVAIAFTLNLC 175 Query: 118 NFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVS 177 + K A + TGS SLF+E IHS DT NQLIL GI S + D PYGY NMRYV+ Sbjct: 176 DMAMKFTAAYLTGSKSLFAEAIHSAMDTCNQLILLLGIRYSAKNPDLLFPYGYGNMRYVT 235 Query: 178 SLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRK 237 SLISG GI G GLS YHG++G+L P+PL +AY+ L ++ +G + + A + Sbjct: 236 SLISGCGIMAFGCGLSMYHGISGLLHPEPLEPLTYAYYALFMSLCFQGTSAITAYREVFA 295 Query: 238 GAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSIL 297 A++AN+S++ YV S+DPS+NVVLLEDTAAV GV +A +++S + +P+PD GSI+ Sbjct: 296 KAKKANISIWNYVRTSADPSLNVVLLEDTAAVTGVGIALCAISLSSFLNSPIPDCCGSIV 355 Query: 298 VGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIR 357 +G +LG VASFII +N LVGRS+P D+I + L D MIR++HDVK +G R Sbjct: 356 IGALLGTVASFIIRTNAAHLVGRSLPQRITDDIVARLNNDPMIRSVHDVKATCLGVEQSR 415 Query: 358 YKAEVDFDGRALTRSYLEK 376 +KAE+DFDGR +TR+YL++ Sbjct: 416 FKAELDFDGRMITRAYLQE 434 >UniRef50_A7Q458 Cluster: Chromosome chr9 scaffold_49, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr9 scaffold_49, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 459 Score = 264 bits (648), Expect = 2e-69 Identities = 138/359 (38%), Positives = 212/359 (59%), Gaps = 5/359 (1%) Query: 80 RDYRREMSHTRSKDNVEEVGLKTR-SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSEC 138 R Y TR+K+ V+ + + + S R V TA+ N F K W T SH + +E Sbjct: 93 RHYINRNFFTRAKE-VKNIEINDQHSQRAVRTALWCNFLVFSLKFGVWLTTSSHVMLAEV 151 Query: 139 IHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGV 198 +HS AD NQ +LAYG+ S + D HPYGY+ R+V SLIS VGIFC+GSG + HGV Sbjct: 152 VHSAADFANQALLAYGLSSSRRAPDAIHPYGYSKERFVWSLISAVGIFCLGSGATIVHGV 211 Query: 199 TGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSV 258 + P + +A V+GG+ + EGA+L+VA+ A++KGA M + +YV R DP+ Sbjct: 212 QNLWTSHPPANIQYAALVIGGSFLIEGASLVVAIHAVKKGAAAEGMKVRDYVWRGHDPTS 271 Query: 259 NVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALV 318 V+ ED AAV G+I+A + + TGNP+ D +GSI+VG +LG VA F+I N AL+ Sbjct: 272 VAVMTEDGAAVTGLIIAGASLVAVNTTGNPIYDPIGSIVVGNLLGMVAIFLIQRNRHALI 331 Query: 319 GRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHD 378 GR+I ++++ ++L+ D ++ A++D K IG R+KAE+DF+G + ++YL++ Sbjct: 332 GRAIDAHDMEKVLNLLKNDPVVDALYDCKSEVIGPGFFRFKAEIDFNGVVVVQNYLKRTG 391 Query: 379 LNALLEDMKKIDTIDDVETFL---LKHGENIVDMLGGEIDRIELKLRKKFPQIRHCDLE 434 ++ +D L +GE +V LG E+DR+E ++++ P IRH D+E Sbjct: 392 RETWARQFREAAKEEDDSALLRMMSNYGEEVVTALGSEVDRLEKEIQELVPGIRHVDIE 450 >UniRef50_Q8H1G3 Cluster: Metal tolerance protein C4; n=3; Magnoliophyta|Rep: Metal tolerance protein C4 - Arabidopsis thaliana (Mouse-ear cress) Length = 457 Score = 255 bits (624), Expect = 2e-66 Identities = 129/350 (36%), Positives = 213/350 (60%), Gaps = 5/350 (1%) Query: 89 TRSKDNVEEVGLKTR-SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVN 147 TR+K V+ + + + S R V TA+ N F K W+ + SH + +E +HS+AD N Sbjct: 98 TRAKQ-VKRIEINDQHSQRAVTTALWCNFLVFSLKFGVWWTSSSHVIMAEVVHSVADFAN 156 Query: 148 QLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPL 207 Q +LAYG+ S + D HPYGY+ R+V SLIS VGIFC+GSG + +GV + P Sbjct: 157 QALLAYGLSSSRRAPDALHPYGYSKERFVWSLISAVGIFCLGSGATIVNGVQNLWTSSPP 216 Query: 208 HDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTA 267 + A V+GG+ + EGA+L+VA+ +++KGA + M++ +Y+ R DP+ V+ ED A Sbjct: 217 PNMELAAVVIGGSFLIEGASLLVAIQSVKKGAAQEGMTIRDYIWRGHDPTSVAVMTEDGA 276 Query: 268 AVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQL 327 AVAG+ +AA+ + + TGNP+ D +GSI+VG +LG VA F+I N AL+GR++ + + Sbjct: 277 AVAGLAIAAASLVAVRMTGNPIYDPIGSIVVGNLLGMVAIFLIQRNRHALIGRAMDDQDM 336 Query: 328 DEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLE---KHDLNALLE 384 ++ L D ++ +++D K IG R+KAE+DF+G+ + ++YL+ + + + Sbjct: 337 SKVLKFLRNDSVVDSLYDCKSEVIGPGSFRFKAEIDFNGQMVVQNYLKRTGREEWAKMFR 396 Query: 385 DMKKIDTIDDVETFLLKHGENIVDMLGGEIDRIELKLRKKFPQIRHCDLE 434 + K + + +GE +V LG E+DR+E ++++ P I+H D+E Sbjct: 397 EAAKNGDDSAMLNIMSNYGEEVVTALGSEVDRLEKEIQELVPGIQHVDIE 446 >UniRef50_Q01GU4 Cluster: Membrane protein HUEL; n=2; Ostreococcus|Rep: Membrane protein HUEL - Ostreococcus tauri Length = 481 Score = 238 bits (582), Expect = 2e-61 Identities = 126/333 (37%), Positives = 195/333 (58%), Gaps = 1/333 (0%) Query: 103 RSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMA 162 R+ + V TAIG N + K+ A+ +GS S+ +E IHS+AD VNQ++L GI S + Sbjct: 147 RALKAVHTAIGCNAAILVCKMGAYGVSGSPSMLAESIHSVADIVNQVLLQVGITNSNKKP 206 Query: 163 DPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVV 222 D YGY R+V SLIS VGIF +G+G S HGV G++DP P + + A VL + Sbjct: 207 DAKFNYGYRRERFVYSLISAVGIFFLGAGFSVMHGVHGLMDPMPTENLWVAISVLSASAA 266 Query: 223 SEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAIS 282 EG +L VA A+R AR +M+L E++ DP+ V EDTAAV G +A + + Sbjct: 267 LEGYSLKVAYEALRDNARAQDMTLTEFIKSGKDPTSLAVFAEDTAAVLGCGIATTALLAC 326 Query: 283 QYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRA 342 TGNP+ D++GSI VG +LG A ++I SN L+GRS+ +++D I + + RD ++ Sbjct: 327 YATGNPMYDSMGSIAVGGLLGATALYLINSNRLLLLGRSLGEDKMDVITAHMRRDPVVEE 386 Query: 343 IHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLN-ALLEDMKKIDTIDDVETFLLK 401 ++ K ++G+ R+ EV+F G+ + YL KH AL + ++ L++ Sbjct: 387 VYFAKSEELGAGAYRFAVEVEFSGKKIVERYLAKHQRRMALHSKFSAANDPKALDAALVQ 446 Query: 402 HGENIVDMLGGEIDRIELKLRKKFPQIRHCDLE 434 +GE+IV +G E+DR+E ++ + P I + D+E Sbjct: 447 YGEDIVQAVGDEVDRLEKEIVEIEPSIHYVDIE 479 >UniRef50_Q4RTG8 Cluster: Chromosome 1 SCAF14998, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14998, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 419 Score = 234 bits (572), Expect = 4e-60 Identities = 122/284 (42%), Positives = 184/284 (64%), Gaps = 15/284 (5%) Query: 168 YGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVL---GGAVVSE 224 YG++NMRY++SLISGVGIF +G+GLS+YHG+ G+L PQP+ W G V+S Sbjct: 136 YGFSNMRYIASLISGVGIFMMGAGLSWYHGIMGLLHPQPMESLLWVSVSGKPGGPEVLSN 195 Query: 225 GATLMV------ALSAIRKGAREANMSLYEYVMR-----SSDPSVNVVLLEDTAAVAGVI 273 GA +V + RE +++ +++R S + A+ + Sbjct: 196 GADPLVLSYRPTVFWQVPWSQREVSLTNISFIIRIFHLFELKRSRSCFAATLLVAINEIK 255 Query: 274 VAASCMAISQYT-GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINS 332 +A +S Y GNP D+LGS+ VGT+LG V++F+I +N AL+GRSI E++ ++ Sbjct: 256 KSARQNGLSFYEYGNPYYDSLGSLGVGTLLGTVSAFLIYTNTEALLGRSIQAERVQKLTE 315 Query: 333 VLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTI 392 LE D +RAIHDVK D+G + +R+KAEVDFDGR +TRSYLEK D++ +L +++++ T Sbjct: 316 FLENDPAVRAIHDVKATDMGLSKVRFKAEVDFDGRVVTRSYLEKQDIDQILSEIQQVKTP 375 Query: 393 DDVETFLLKHGENIVDMLGGEIDRIELKLRKKFPQIRHCDLEIL 436 +++E F+LKHGENI+D LG E+DR+E L+++ P++RH DLEIL Sbjct: 376 EELENFMLKHGENIIDTLGAEVDRLEKGLKQRNPEVRHVDLEIL 419 Score = 74.5 bits (175), Expect = 5e-12 Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 1/116 (0%) Query: 1 MRAMTEYLLKQSDLESLPKVLRRSPYESEPPITVYYRRDVEAKAIEIWGSKXXXXXXXXX 60 +RAM E+ LK SDLE L ++ RRSP++ TV+ R DVEAKAI++WGS+ Sbjct: 23 VRAMNEFCLKPSDLEQLRRIRRRSPHDDTEAFTVFLRSDVEAKAIDVWGSQEALARERNL 82 Query: 61 XXXXXXXXXQDVFTVKRRLRDYRREMSHTRSKDNVEEVGLKTRSGRVVLTAIGING 116 +++F ++ L++Y+ +T+ + L+ G+VV+ AI + G Sbjct: 83 RKEMEKEYQENIFRNQQLLKEYKHFWGNTKPRAGKRTTFLQ-GPGKVVMVAICMYG 137 >UniRef50_A6G134 Cluster: Predicted Co/Zn/Cd cation transporter; n=1; Plesiocystis pacifica SIR-1|Rep: Predicted Co/Zn/Cd cation transporter - Plesiocystis pacifica SIR-1 Length = 331 Score = 220 bits (537), Expect = 7e-56 Identities = 125/335 (37%), Positives = 197/335 (58%), Gaps = 6/335 (1%) Query: 100 LKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 + + G V+ IG N + K A++ TGS ++FSE IHS AD NQ +L GI S Sbjct: 1 MASSKGAVLGALIG-NSVLTVIKFTAFWLTGSGAMFSEAIHSAADAANQGLLFVGIRSSE 59 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGG 219 + AD YGY RY+ SL+S VGIF GSGL+ YHGV L P+P+ + +Y VLG Sbjct: 60 RPADNAFHYGYGYDRYLFSLLSAVGIFVFGSGLTVYHGVHSALHPEPVESSWISYAVLGI 119 Query: 220 AVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCM 279 +++ +G L A+ AI A++ + SL+ Y+ +SDP+V VLLED A GV+VAA + Sbjct: 120 SLLVDGVVLAGAVRAI--WAKKGSQSLFAYLRTTSDPTVAAVLLEDAVATLGVLVAAGAI 177 Query: 280 AISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFM 339 A+++ TGN L DA+G+I +G +LG VA ++ + N L+G +IP + + + LE+ Sbjct: 178 ALTEVTGNSLFDAIGAIAIGGMLGLVAIWLGVKNRELLLGPAIPKRIWEGVMAYLEQHPA 237 Query: 340 IRAIHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDVETFL 399 + + K +G+ R+ AE++FDGR L + D + + + + + + F Sbjct: 238 VGKVRKPKSRVVGAGQFRFAAEIEFDGRYLGEKLVGVVDEHVANDALAE---VAGRKAFA 294 Query: 400 LKHGENIVDMLGGEIDRIELKLRKKFPQIRHCDLE 434 + GE +V ++G E+D IE +LRK++P++ H D+E Sbjct: 295 GEFGERLVTLVGDEVDEIERELRKRYPELVHVDIE 329 >UniRef50_A6C709 Cluster: Cation efflux protein; n=1; Planctomyces maris DSM 8797|Rep: Cation efflux protein - Planctomyces maris DSM 8797 Length = 335 Score = 200 bits (489), Expect = 4e-50 Identities = 115/336 (34%), Positives = 190/336 (56%), Gaps = 7/336 (2%) Query: 101 KTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQ 160 ++ S V+ A+ N + K + TGS ++ SE IHS+AD +NQ++L G+ ++ Q Sbjct: 3 QSNSRFAVIAALIGNALITVAKGATFLITGSGAMLSETIHSVADFLNQVLLLIGLVRADQ 62 Query: 161 MADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPL--HDFYWAYFVLG 218 D YGY RYV +LIS VGIF +G G++ YHGV + P L + WA L Sbjct: 63 APDKRFEYGYAGERYVWALISAVGIFFLGCGVTIYHGVQSLFHPPDLVLGEMNWAIAALL 122 Query: 219 GAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASC 278 A+V +G +AL K A ++Y+ + +DP+ V+LED AA GVI+A Sbjct: 123 FALVIDGIVFYLALKGEWKNAAREGRPFHQYLRKEADPAAVAVILEDGAACVGVIIALIS 182 Query: 279 MAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDF 338 + ++Q TG DA+GSI +G +LGG+A ++I+ N LVG SIP +++ +L+ + Sbjct: 183 ILLTQMTGQHYWDAIGSIGIGILLGGIAIWLIIRNQELLVGPSIPPRTREQVERILKNNP 242 Query: 339 MIRAIHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDVETF 398 ++ + D++ + + R KA++ F+ + L++ L+K L A E I + D E F Sbjct: 243 LVEDVLDLRSRILSIDNYRIKADLSFNSQELSKR-LKKKALAAYPE----IKSEQDFELF 297 Query: 399 LLKHGENIVDMLGGEIDRIELKLRKKFPQIRHCDLE 434 + E+++ ML EID+IE +++++ P+ +H DLE Sbjct: 298 CQNYTEDVLTMLADEIDKIEAEIQRQVPEAQHLDLE 333 >UniRef50_A0M1Q8 Cluster: CDF family cation efflux protein; n=1; Gramella forsetii KT0803|Rep: CDF family cation efflux protein - Gramella forsetii (strain KT0803) Length = 305 Score = 176 bits (428), Expect = 1e-42 Identities = 100/291 (34%), Positives = 156/291 (53%), Gaps = 2/291 (0%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMAD 163 S + AIG N + K A F+TGS ++ +E IHSL DT N L+L GI +S Q D Sbjct: 6 SNIAIYGAIGANLLIAISKFLASFFTGSSAMLAEGIHSLVDTGNGLLLLLGIKRSKQKPD 65 Query: 164 PDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVS 223 HP+GY Y S + + IF +G G + Y G+ I DP + D W Y+VLG A+V Sbjct: 66 KMHPFGYGKEVYFWSFVVSILIFALGGGFAIYEGIHAIQDPHVIEDPTWNYWVLGAAIVF 125 Query: 224 EGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQ 283 EG L +AL K + + +L + +++S D + V++EDTAAV G+ VA + +SQ Sbjct: 126 EGTALYLALKTFNKSRKHKSKNLIKNIIKSKDAATFAVIIEDTAAVVGLTVALIGVFLSQ 185 Query: 284 YTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAI 343 GNP D SI++GTIL VA+F+ + G L+G S E +++I++++ + A Sbjct: 186 VFGNPYLDGAASIVIGTILLAVATFLAKESKGLLLGESAHDEVIEDIDNLINSKAYVNAS 245 Query: 344 HDVKGIDIGSNLIRYKAEVDF-DGRALTRSYLEKHDL-NALLEDMKKIDTI 392 + + + G + I E+D D + DL N ++++ KI + Sbjct: 246 NIPQTMHFGPDKILLIVEIDLVDNLEFLEAEKIVDDLRNEIMQEKPKIKEV 296 >UniRef50_Q1Q491 Cluster: Putative uncharacterized protein; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Putative uncharacterized protein - Candidatus Kuenenia stuttgartiensis Length = 337 Score = 163 bits (395), Expect = 1e-38 Identities = 103/339 (30%), Positives = 176/339 (51%), Gaps = 12/339 (3%) Query: 100 LKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 +K S VVL+AI N + K W + S S+ +E IHS ADT NQ++L GI S Sbjct: 7 VKDDSVVVVLSAICGNLLLTIAKFSGWLISRSPSMLAEAIHSFADTANQILLYVGIQHSR 66 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPL--HDFYW-AYFV 216 + P+G + RY+ +LIS VGIF VG G++ YHG++ + P + YW + + Sbjct: 67 SGPSREFPWGQGSSRYLWNLISAVGIFFVGFGVTTYHGISSLFKPHEAFRSELYWLSITI 126 Query: 217 LGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAA 276 L + EG L +A ++K ++ SL V+ D ++ VLLED+ AV GV+ A Sbjct: 127 LALSFFVEGYVLTIAYKKLKK--KQDRRSLRNIVLSGDDSTITAVLLEDSIAVLGVVTAL 184 Query: 277 SCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLER 336 + + +S + LPDA+ SI++G LG +A + N L+G ++ ++ +I + Sbjct: 185 TGLWLSHIYQSHLPDAVASIIIGIFLGIMAVLLAFVNGRLLIGMAVSEKKEKDIRQFIGI 244 Query: 337 DFMIRAIHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDVE 396 + + +K +G N+++ AE++F G + D + D + I ++ Sbjct: 245 YPSVEKVISLKTQILGPNMVKLTAEIEFHGGIM-------FDRKQVEADAELIRQGEEPL 297 Query: 397 TFLLKHGENIVDMLGGEIDRIELKLRKKFPQIRHCDLEI 435 L+ E V ++G EI+++E +R++FP+I LE+ Sbjct: 298 PILVDTIERTVRVVGNEINKLERAIRERFPEISSISLEV 336 >UniRef50_Q2SF35 Cluster: Predicted Co/Zn/Cd cation transporters; n=2; Gammaproteobacteria|Rep: Predicted Co/Zn/Cd cation transporters - Hahella chejuensis (strain KCTC 2396) Length = 313 Score = 156 bits (379), Expect = 9e-37 Identities = 88/261 (33%), Positives = 142/261 (54%), Gaps = 2/261 (0%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMAD 163 S +V+ A+ N L K A +TGS ++FSE +HS+ DT NQ++L +G+ +S + A Sbjct: 5 SKKVIYAALVGNALVALTKFAAAAFTGSSAMFSEGVHSVVDTGNQVLLLHGMKRSQRPAS 64 Query: 164 PDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVS 223 D P+G+ Y S I + IF +G+G+S Y GV IL PQ + + Y VL A++ Sbjct: 65 EDFPFGHGKEIYFWSFIVAILIFALGAGISIYEGVEHILHPQVVENPVVNYIVLSLAIIF 124 Query: 224 EGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQ 283 EG +A+ R + M +E V R DPS+ VVL ED AA+ G++VA + + Q Sbjct: 125 EGFAFGMAVKEFRNA--KGRMGYFEAVQRGKDPSLFVVLFEDAAAMLGLLVALGGIIMGQ 182 Query: 284 YTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAI 343 TGNP+ D + S+++G ILG A ++ + G L+G S + + I + + + Sbjct: 183 VTGNPVYDGVASVIIGCILGLTALWLAVETKGLLIGESASKKVVKAIREMTCAIPGVEHV 242 Query: 344 HDVKGIDIGSNLIRYKAEVDF 364 ++V + +G + + VDF Sbjct: 243 NEVLTMHMGPDFVLVNLSVDF 263 >UniRef50_Q3JA92 Cluster: Cation efflux protein; n=4; Bacteria|Rep: Cation efflux protein - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 321 Score = 156 bits (378), Expect = 1e-36 Identities = 90/263 (34%), Positives = 142/263 (53%), Gaps = 3/263 (1%) Query: 104 SGR--VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQM 161 SGR V+ AI N + K A +++GS ++ SE IHS+ DT N+L+L G+ +S + Sbjct: 6 SGRLLVIYGAIAANFFIAVAKFIAAYFSGSSAMLSEGIHSMVDTGNELLLLLGVKRSNKP 65 Query: 162 ADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAV 221 AD HP+GY Y SLI + +F +GSG+S Y G+T +L P + D W+Y VLG A Sbjct: 66 ADEQHPFGYGKELYFWSLIVAIALFGIGSGMSIYEGITHLLHPTEITDPTWSYIVLGIAF 125 Query: 222 VSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAI 281 V+EG + ++AL + ++ + S ++ + S DPSV V ED+AA+AGV+VA + + Sbjct: 126 VAEGISWIIALKEL-LASKNRDRSFWQALRISKDPSVFTVFCEDSAALAGVVVAFLGVYL 184 Query: 282 SQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIR 341 N D SI++G IL VA F+I LVG S + + I+ + D + Sbjct: 185 GHTLNNHYFDGSASIVIGLILAAVALFLIYEGKHLLVGESADPQIVRHIHEIANTDPAVA 244 Query: 342 AIHDVKGIDIGSNLIRYKAEVDF 364 + + G + + ++ F Sbjct: 245 DLRRPLTMHFGPDQVLLNLDIKF 267 >UniRef50_Q1QCT7 Cluster: Cation diffusion facilitator family transporter; n=2; Proteobacteria|Rep: Cation diffusion facilitator family transporter - Psychrobacter cryohalolentis (strain K5) Length = 365 Score = 156 bits (378), Expect = 1e-36 Identities = 103/276 (37%), Positives = 141/276 (51%) Query: 91 SKDNVEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLI 150 SK K+ S VL A+G N + K A F TGS S+ +E HS AD N + Sbjct: 43 SKSTPSHDDKKSSSLTTVLIAVGANLIIAIAKTVAAFMTGSASMIAESAHSWADAGNGTL 102 Query: 151 LAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDF 210 L KSV+ AD HP GY YV S+I+ G+F GS +S Y G+T + ++ Sbjct: 103 LIVAEKKSVKPADKSHPLGYGKESYVWSMIAAFGVFMAGSVVSIYTGITEWNAAETETNY 162 Query: 211 YWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVA 270 + +L A V EG +L A +K N+S YVM +S+P++ V ED AAV Sbjct: 163 TIGFIILAVAFVLEGFSLTQAYLQSKKHGEAINVSAIGYVMDTSNPTLRGVFFEDLAAVI 222 Query: 271 GVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEI 330 G++VAA+ MA+ YTG P DALGSI+VG +L VA F+I N LVG + + D I Sbjct: 223 GLVVAAAAMAMHAYTGEPFWDALGSIIVGILLAVVAVFLISRNRDFLVGYRVSEKMHDYI 282 Query: 331 NSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDG 366 S L + I ++ + +G I A VD G Sbjct: 283 LSELIKHPDIDSVSYLHLEWVGPKKIFMVAAVDIAG 318 >UniRef50_Q0F0R3 Cluster: Predicted Co/Zn/Cd cation transporters; n=1; Mariprofundus ferrooxydans PV-1|Rep: Predicted Co/Zn/Cd cation transporters - Mariprofundus ferrooxydans PV-1 Length = 323 Score = 150 bits (363), Expect = 8e-35 Identities = 92/293 (31%), Positives = 157/293 (53%), Gaps = 10/293 (3%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMAD 163 S R VLTA+ N + K +F +GS +L +E +HSLADT NQ +L G+ +S + AD Sbjct: 5 STRTVLTALAGNSLVTMAKFFGFFVSGSSALLAEAVHSLADTANQGLLYLGLRRSTRKAD 64 Query: 164 PDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVS 223 +H +GY RY +L+S V IF +G G + H V + D + + ++G + ++ Sbjct: 65 SEHHFGYGQERYFWNLVSAVTIFFLGCGYTIMHAVEQLHDAHQPELSWIPFLIIGVSFLA 124 Query: 224 EGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQ 283 EG +L VAL+ R+ A A L Y + + DP+ VL+ED+ AV G++VA M ++ Sbjct: 125 EGYSLGVALTEFRQQAGAAGKPLRTYFVETRDPTTLAVLIEDSVAVLGLMVALIGMGLAA 184 Query: 284 YTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLER----DFM 339 +TG+ + D + +I +G ++G +A F+ N L+ RS DE+N++ R D Sbjct: 185 WTGSAMFDGVAAICIGLMMGVLALFLASINRKYLLNRSD-----DEVNNIAARVWQADRQ 239 Query: 340 IRAIHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTI 392 ++ + V I + + AEV+ A+ + +++ + M+K+D I Sbjct: 240 VQHVQRVNSIVLSPDDTLLMAEVELREEAIFAD-MSADEVSRAIRFMRKLDMI 291 >UniRef50_Q98D48 Cluster: Mll4860 protein; n=10; Proteobacteria|Rep: Mll4860 protein - Rhizobium loti (Mesorhizobium loti) Length = 317 Score = 146 bits (354), Expect = 1e-33 Identities = 84/262 (32%), Positives = 141/262 (53%), Gaps = 2/262 (0%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMAD 163 S V+ A+ N L K A F+TGS ++ SE +HSL DT N +L YG+H++ + AD Sbjct: 7 SKTVIYAALAGNLAIALTKFAAAFFTGSSAMLSEGVHSLVDTGNGGLLLYGMHRAARPAD 66 Query: 164 PDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVS 223 HP G+ Y S I + +F +G+G+S Y G+ I+ P+P+ + Y VLG + + Sbjct: 67 RTHPLGHGRELYFWSFIVALLVFALGAGVSLYEGIIHIIAPEPVANVKVNYIVLGLSFLF 126 Query: 224 EGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQ 283 EG++ +VAL R+ + S + + S DPSV VL ED+AA+ G+IVA + + ++ Sbjct: 127 EGSSWLVALKEFRR--EKGRQSWLQALQSSKDPSVYTVLFEDSAALLGLIVAFAGILAAE 184 Query: 284 YTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAI 343 P D SI + ILG A F+ + G L+G E ++ +++++D ++ Sbjct: 185 LLEMPELDGAASIGIAFILGATAIFLARESKGLLIGEPASPEVQKKVLAIVQQDSAVQRA 244 Query: 344 HDVKGIDIGSNLIRYKAEVDFD 365 + V + +G I ++F+ Sbjct: 245 NGVLTVHMGPREIVAGLSIEFE 266 >UniRef50_A6EC28 Cluster: Predicted Co/Zn/Cd cation transporter; n=1; Pedobacter sp. BAL39|Rep: Predicted Co/Zn/Cd cation transporter - Pedobacter sp. BAL39 Length = 318 Score = 145 bits (351), Expect = 2e-33 Identities = 76/232 (32%), Positives = 130/232 (56%), Gaps = 2/232 (0%) Query: 103 RSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMA 162 R+ + + +A+ N + K A ++ S S+ SE IHSL DT+NQ++L YG+ +S + A Sbjct: 21 RNNKSIYSALAANLLIAITKFIAGAFSNSSSMISEGIHSLVDTINQVLLLYGLKRSRRPA 80 Query: 163 DPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVV 222 D P+GY Y S I + IF +G G+S Y G+ I++P+PL D W Y V+G +++ Sbjct: 81 DAGRPFGYGKELYFWSFIVAIMIFGLGGGISIYQGIDHIIEPEPLGDPTWNYVVIGLSIL 140 Query: 223 SEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAIS 282 E ++L +A+ A + ++ +++S DPS +VL ED+AAV G+++ M I Sbjct: 141 FESSSLYIAIKEF--NALRNGLGWWKAIVKSKDPSSFLVLFEDSAAVMGLLIVLVFMIIG 198 Query: 283 QYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVL 334 + P D + S+ VG +L V++ + + L+G I E +I S++ Sbjct: 199 HHYQLPFMDGVASVCVGLLLVLVSAILARESRSLLMGEGIAPETQQKITSII 250 >UniRef50_A3IUW6 Cluster: Predicted Co/Zn/Cd cation transporters; n=3; Bacteria|Rep: Predicted Co/Zn/Cd cation transporters - Cyanothece sp. CCY 0110 Length = 303 Score = 144 bits (348), Expect = 5e-33 Identities = 80/261 (30%), Positives = 137/261 (52%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMAD 163 S R + A+ N + K +GS ++ SE IHS+ D++N+++L YG+ +S + D Sbjct: 5 STRTIYAAMIANIAIGVAKFFGAAISGSSAMLSEGIHSVVDSINEVLLLYGLKRSKKEPD 64 Query: 164 PDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVS 223 DHP G+ Y SL+ V IF +G G+S Y G D + + +Y VL A V Sbjct: 65 EDHPLGHGQEIYFWSLVVAVLIFALGGGISIYEGFKSFHDSRESTNAIVSYGVLSIAAVF 124 Query: 224 EGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQ 283 EG L +++ + + N++ ++ + RS +P+ VV+ EDTAA+ G++VA + +S+ Sbjct: 125 EGTALFISVQEFNQERSDNNINFWKALRRSKNPTTFVVIFEDTAALLGIVVAILGVFLSE 184 Query: 284 YTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAI 343 TG D L SI++G IL VA +++ G L+G S E D I +++ +D + + Sbjct: 185 LTGTIFYDGLASIIIGVILTIVAIVLVIETKGLLIGESAFPEVRDSIKNIVVKDTSVYKV 244 Query: 344 HDVKGIDIGSNLIRYKAEVDF 364 + +G I ++F Sbjct: 245 ESPITLQLGPTDILLALSIEF 265 >UniRef50_A1SQA1 Cluster: Cation diffusion facilitator family transporter precursor; n=3; Actinomycetales|Rep: Cation diffusion facilitator family transporter precursor - Nocardioides sp. (strain BAA-499 / JS614) Length = 298 Score = 144 bits (348), Expect = 5e-33 Identities = 85/256 (33%), Positives = 132/256 (51%) Query: 111 AIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGY 170 A+ NG + K A TGS S+ +E HS ADT N++ L K + D +HP GY Sbjct: 2 ALVANGLLAIAKSVAAAVTGSASMVAEAAHSWADTGNEVFLLVAERKGSRPRDEEHPRGY 61 Query: 171 TNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMV 230 Y+ SL++ G+F G+ +S +HG+T + + + Y VLG A V EG + Sbjct: 62 GRSTYIWSLVAAFGLFSAGAVVSLWHGITELTGEEAAPSYAVNYIVLGVAFVLEGVSFAQ 121 Query: 231 ALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLP 290 A + AR + +V R+S+P++ V ED+AA+AG+++A + +A+ Q TG + Sbjct: 122 ATRQVHGAARRFGLHPLRFVSRTSNPTLRAVFFEDSAALAGILLAGAGIALHQVTGEAVF 181 Query: 291 DALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGID 350 DALGSI VG +LG VA F++ N+ L+G + E + + L I I + Sbjct: 182 DALGSIAVGILLGFVAVFLMRRNMDYLLGEGLTPELRSRVIAQLLEHPQIDRITYLHVEY 241 Query: 351 IGSNLIRYKAEVDFDG 366 +G + A VD G Sbjct: 242 VGPQRLFVVAAVDLTG 257 >UniRef50_Q0BR38 Cluster: Cobalt-zinc-cadmium resistance protein czcD; n=2; Proteobacteria|Rep: Cobalt-zinc-cadmium resistance protein czcD - Granulobacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) Length = 341 Score = 142 bits (343), Expect = 2e-32 Identities = 79/261 (30%), Positives = 139/261 (53%), Gaps = 2/261 (0%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 VV A+G N + K A TGS ++ SE +HSL DT NQL++ +G+ + + A P+H Sbjct: 36 VVFAALGGNFAIAVMKFAAAASTGSSAMLSEAVHSLVDTGNQLLMLWGMRCAARPATPEH 95 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGA 226 P+G+ Y S + V IF +G+G+S + GV + P + + Y VLGG+ V EG Sbjct: 96 PFGHGLELYFWSFMVAVLIFGLGAGVSIFEGVEKLRHPVSVTHVWPNYLVLGGSFVFEGI 155 Query: 227 TLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTG 286 ++A+ A + ++ + + E S DP+V VL EDTAA+ G++ A + ++Q+ Sbjct: 156 VWLLAMRAFLR--QKGRLGVLEAAQASKDPTVFTVLFEDTAALLGLLTAGVGLGLAQWLH 213 Query: 287 NPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDV 346 P DA+ S+++G IL A F+ + L+G S P + I ++ + + +++ Sbjct: 214 QPAFDAIASLVIGGILAVTALFLARESRSLLIGESAPLAVREHIRRIVASEPGVVCANEI 273 Query: 347 KGIDIGSNLIRYKAEVDFDGR 367 + G + + +DF+ + Sbjct: 274 LTMHFGPSEVLVAISMDFENQ 294 >UniRef50_Q9L081 Cluster: Putative membrane transport protein; n=1; Streptomyces coelicolor|Rep: Putative membrane transport protein - Streptomyces coelicolor Length = 326 Score = 141 bits (341), Expect = 4e-32 Identities = 84/243 (34%), Positives = 132/243 (54%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K A +GS ++ SE HS+ADTV +++L + +SV+ AD DHP G+ RY+ +L++ Sbjct: 34 KAVAGVISGSSAMLSEAAHSVADTVTEVLLLTSLKRSVRPADEDHPLGHGPERYIWALLA 93 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGARE 241 V F G+ S Y G+ + + L D +Y VL A V EG +L L +R A Sbjct: 94 AVATFVGGAVFSLYDGIHTLTHGEDLGDPLVSYIVLAVAFVLEGYSLRTGLRQVRGEAAH 153 Query: 242 ANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTI 301 +S Y+ R+ D +V V++ED+AA+AG+++AA + Q TG+ + DA+ S+ +G + Sbjct: 154 HRVSFGRYLRRTPDTAVKAVVMEDSAALAGLLLAAGGLLGGQLTGSGVWDAVASLCIGAL 213 Query: 302 LGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAE 361 L VA + SN LVGR + D I + L D I A+ ++ + G A+ Sbjct: 214 LLYVAWVLGRSNAEFLVGRPLSRSVRDRIRAELVADEHIEAVLELTTLVQGPREALVAAK 273 Query: 362 VDF 364 VDF Sbjct: 274 VDF 276 >UniRef50_A5V609 Cluster: Cation diffusion facilitator family transporter precursor; n=2; Sphingomonas|Rep: Cation diffusion facilitator family transporter precursor - Sphingomonas wittichii RW1 Length = 308 Score = 140 bits (339), Expect = 7e-32 Identities = 82/259 (31%), Positives = 135/259 (52%), Gaps = 2/259 (0%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 ++ A+ N + K A TGS ++ +E HS+ D++NQL+L YG +SV+ D H Sbjct: 10 ILFAALAANLGIAVAKFVAAAITGSSAMLTEGFHSVVDSLNQLLLLYGQKRSVRPPDERH 69 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGA 226 P GY Y S + + IF G+GLS Y GV +LDP+P+ + Y VL +++ EGA Sbjct: 70 PLGYGRELYFWSFVVAILIFSTGAGLSIYEGVLHVLDPEPIRTPWVNYVVLALSLLLEGA 129 Query: 227 TLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTG 286 + +A+ GA + +E V +S DP +VL ED+AA+ G+ VA + + +S TG Sbjct: 130 SWGIAVREF--GAAKGEHGWWEAVRQSKDPPSFIVLFEDSAAMFGLFVAGAGITLSLLTG 187 Query: 287 NPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDV 346 + D + SI++G L GVA + L+G + + ++R + ++++ Sbjct: 188 DARWDGVASIVIGLALAGVALALAREAKDLLIGEPADPALEAAVRAAIDRRPEVTGVNEI 247 Query: 347 KGIDIGSNLIRYKAEVDFD 365 + IG I VDF+ Sbjct: 248 TTVHIGPQAIFLGLAVDFE 266 >UniRef50_Q6A747 Cluster: Cation transport protein; n=1; Propionibacterium acnes|Rep: Cation transport protein - Propionibacterium acnes Length = 343 Score = 134 bits (323), Expect = 6e-30 Identities = 91/289 (31%), Positives = 144/289 (49%), Gaps = 12/289 (4%) Query: 87 SHTRSKDN-VEEVGLKTRSGR-VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLAD 144 +H + N +E T+ GR ++ A N + K AW TG+ S+ +E IHS+AD Sbjct: 4 AHAAQRPNGAKEPANPTQGGRKAIIAAASANLAIAVTKAIAWALTGASSMLAEAIHSVAD 63 Query: 145 TVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSF---YHGVTGI 201 T NQ++L G +S + AD DHP+GY RY+S I + IF +G + YH + Sbjct: 64 TANQVVLMMGGKESHKEADEDHPFGYETARYLSGFIVAIVIFTLGGLFALYEAYHKIGAT 123 Query: 202 L--DPQPLHDFYWAYFVLGGAVVS---EGATLMVALSAIRKGAREANMSLYEYVMRSSDP 256 L P L D W + L ++S EGA+L AL + RE M++ +Y+ ++ P Sbjct: 124 LGGHPDELLDSQWWWVPLAVVMISLCAEGASLRTALKESSQD-RE-GMTILQYIRKAKAP 181 Query: 257 SVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGA 316 + VV+LED+AAV G+I A + ++ T NP+ D +GS +G +L VA + Sbjct: 182 ELPVVMLEDSAAVLGLIFAFLGVGLTLLTHNPIFDGIGSACIGILLVVVAGVLSREMKSL 241 Query: 317 LVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFD 365 L G S E + L + ++ +K + +G I A++ D Sbjct: 242 LEGESAAPESRKAVYDALIHSDGVDSVIYMKTVHLGPETILLAAKIAVD 290 >UniRef50_A6W6F7 Cluster: Cation diffusion facilitator family transporter; n=1; Kineococcus radiotolerans SRS30216|Rep: Cation diffusion facilitator family transporter - Kineococcus radiotolerans SRS30216 Length = 353 Score = 133 bits (321), Expect = 1e-29 Identities = 86/280 (30%), Positives = 140/280 (50%), Gaps = 2/280 (0%) Query: 86 MSHTRSKDNVEEVGLKT-RSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLAD 144 MS T S N G S VL A+G N + K A TGS ++ +E HS+AD Sbjct: 1 MSSTVSPTNHRSPGTGGGESTATVLVALGANALIAVAKGVAAVVTGSAAMAAETAHSVAD 60 Query: 145 TVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGIL-D 203 TVN++ L + S + AD +HP GY RY +L++ IF G+ S Y GV + + Sbjct: 61 TVNEVFLLTALRTSARPADREHPLGYGRARYFWALVAAGSIFVTGALYSAYEGVEALTSE 120 Query: 204 PQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLL 263 L +Y VL A V EG++L+ L R ARE E++ + DP+ V+ Sbjct: 121 SHDLESPLVSYVVLAVAFVLEGSSLLKGLKQTRGEAREKRQGFREFLRTTDDPTATTVVF 180 Query: 264 EDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIP 323 ED+AA+AG+++A + A+ Q TG+ + D + S+ + +L VA + +N+ L G Sbjct: 181 EDSAALAGLLLAGAGTAMHQVTGSGVYDGIASLCIALLLALVAVRLARTNMRLLTGVQAD 240 Query: 324 HEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVD 363 + + L + + A+ D+ + +G++ + A +D Sbjct: 241 PRLVSSVLVHLGDEPEVEAVVDLLTVQLGTDQVLVCARLD 280 >UniRef50_Q6AHA9 Cluster: Cation transporter; n=1; Leifsonia xyli subsp. xyli|Rep: Cation transporter - Leifsonia xyli subsp. xyli Length = 320 Score = 132 bits (319), Expect = 2e-29 Identities = 84/264 (31%), Positives = 139/264 (52%), Gaps = 4/264 (1%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R ++ A N L KL AW ++GS S+ +E +HS+AD NQL+L G ++ + AD Sbjct: 8 RAIVAAFAANLGIALTKLIAWLFSGSSSMLAEGVHSIADCGNQLLLLLGGRRAKKKADRK 67 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 HP+GY RYV + + + +F G S Y GV + L + + VL A+ E Sbjct: 68 HPFGYGRERYVYAFVVSIVLFSAGGVFSLYEGVEKLTHRHSLENSWLPLLVLLIAIGLES 127 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 +L A+ R + ++S +++ R+ P + VVLLED AA+AG++ A +++S T Sbjct: 128 FSLRRAIHESR--PHKQSISWLQFIRRAKAPELPVVLLEDVAALAGLLFALIGISLSVLT 185 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEI-NSVLERDFMIRAIH 344 G+ + DA+G++L+GT+L VA + LVG I +VL + R IH Sbjct: 186 GDAVWDAIGTLLIGTLLIVVALVLGFETKSLLVGEGASDSDAAAIERAVLSGGEVERIIH 245 Query: 345 DVKGIDIGSNLIRYKAEVDFDGRA 368 +K + +G + + + A+V G + Sbjct: 246 -MKTLYLGPDELLFGAKVAMSGES 268 >UniRef50_A0GH18 Cluster: Cation diffusion facilitator family transporter; n=4; Burkholderiales|Rep: Cation diffusion facilitator family transporter - Burkholderia phytofirmans PsJN Length = 327 Score = 129 bits (311), Expect = 2e-28 Identities = 91/273 (33%), Positives = 144/273 (52%), Gaps = 5/273 (1%) Query: 100 LKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 +K S + + A+ N + K A +TGS S+F+E IHS AD NQL+L +G+ ++ Sbjct: 27 MKEESPKAIFYALAANLGIAICKFAAAAFTGSGSMFAEAIHSTADCGNQLLLLFGLREAR 86 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGG 219 + A P HP G SL+ + +F VG S Y GV + +PL Y A VLG Sbjct: 87 KPASPLHPMGGGREINFYSLLVALLLFFVGGAFSVYEGVHRLFVREPLQYAYVALAVLGV 146 Query: 220 AVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCM 279 +VV E +L A+ IRK + S++ + + + + VV ED AA+AG+ +A + + Sbjct: 147 SVVLEALSLWGAVKEIRK--THPDKSMWRWFRETRESELLVVAGEDIAALAGLAMAFAAV 204 Query: 280 AISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFM 339 ++ TGNP+ DALGSI VG +L +A + +VG S E I + L Sbjct: 205 LLTMMTGNPVYDALGSIGVGVLLMVIAWLVAREVKSMIVGESASPEVRRAIEAHLRGRTE 264 Query: 340 IRAIHDVKGIDIGSN-LIRYKAE-VDF-DGRAL 369 IR+I ++ + G + ++ +AE +D+ GRA+ Sbjct: 265 IRSIINMITLQWGRHVVVAVQAEMIDYASGRAM 297 >UniRef50_A5P265 Cluster: Cation diffusion facilitator family transporter; n=1; Methylobacterium sp. 4-46|Rep: Cation diffusion facilitator family transporter - Methylobacterium sp. 4-46 Length = 316 Score = 124 bits (300), Expect = 3e-27 Identities = 73/259 (28%), Positives = 121/259 (46%), Gaps = 2/259 (0%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 VV A+ N K A YTGS ++ +E +HS DT NQ +L YG+ ++ + AD H Sbjct: 9 VVYAALAGNLAIAATKFAAALYTGSSAMVTEAVHSFVDTGNQGLLLYGMRRAARPADDSH 68 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGA 226 +G+ Y S + + IF G + Y G+ I P+P+ + V+ A EG Sbjct: 69 NFGHGLELYFWSFVVALMIFSAGGAFAIYEGIEKIRHPEPIDSAWVNVAVIAAAAFFEGL 128 Query: 227 TLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTG 286 + A +R+ R A + L+ V RS DPS V+LED AA+ G+ A + + G Sbjct: 129 SFRTAWREMRQ--RFARLPLWRAVARSKDPSTFAVVLEDGAALIGLAFALAGSVAVSWLG 186 Query: 287 NPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDV 346 P D + S+ +G +L A + L G S +++ ++L D + + V Sbjct: 187 WPPGDGVASVAIGLLLIATAFVLFRETRSLLTGESASPRLIEQATAILRADPRVIGVSRV 246 Query: 347 KGIDIGSNLIRYKAEVDFD 365 + + +G+ + +D D Sbjct: 247 RSLHLGTTTVLLAVSLDLD 265 >UniRef50_A7D914 Cluster: Cation diffusion facilitator family transporter; n=2; Methylobacterium extorquens PA1|Rep: Cation diffusion facilitator family transporter - Methylobacterium extorquens PA1 Length = 340 Score = 122 bits (293), Expect = 2e-26 Identities = 76/267 (28%), Positives = 130/267 (48%), Gaps = 12/267 (4%) Query: 108 VLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHP 167 + TA G N K F TGS ++ +E HSL DT NQL+L G+ ++ + AD HP Sbjct: 8 IYTAAGANLAIAAAKFVGAFLTGSTAMLAEGAHSLVDTANQLLLLVGLKRAKKPADAKHP 67 Query: 168 YGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQP----------LHDFYWAYFVL 217 +GY Y + I + IF G + Y G I P+P L F+ +L Sbjct: 68 FGYGREVYFYAFIVALFIFLGGGIFAIYEGAHKIEHPEPSADATLFGVQLSGFWVNVSIL 127 Query: 218 GGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAAS 277 G A+++EG + VA+ A A + S + RS DP++ +L+ED AA+ G+++A Sbjct: 128 GFAILAEGYSCFVAVKAF--WAEKGQRSAITAIQRSKDPALYTILVEDVAALIGLVIAIG 185 Query: 278 CMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERD 337 + ++ P D SI +G +L G++ F+++ G L+G + + I + + + Sbjct: 186 GVVLAHVLDKPALDGWASIGIGLVLIGMSIFLMIETHGLLIGEAADPAVVRTIQAAVSEE 245 Query: 338 FMIRAIHDVKGIDIGSNLIRYKAEVDF 364 ++ ++ V +G + I +DF Sbjct: 246 SAVQHVNAVLTQHLGPSDILVNLSLDF 272 >UniRef50_A2XRM0 Cluster: Putative uncharacterized protein; n=1; Oryza sativa (indica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. indica (Rice) Length = 298 Score = 120 bits (288), Expect = 1e-25 Identities = 58/145 (40%), Positives = 91/145 (62%) Query: 203 DPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVL 262 D P + ++A V+GG+ + EGA+L+VA+ A+RKGA MS+ +Y+ R DP+ V+ Sbjct: 91 DANPPENIHYAALVIGGSFLIEGASLLVAIKAVRKGAAAEGMSIRDYIWRGHDPTSVAVM 150 Query: 263 LEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSI 322 ED AAV G+ +A + + Q TGN + D +GSI+VG +LG VA F+I N AL+GR+I Sbjct: 151 TEDGAAVTGLAIAGASLVAVQTTGNAMYDPIGSIIVGNLLGMVAIFLIQRNRHALIGRAI 210 Query: 323 PHEQLDEINSVLERDFMIRAIHDVK 347 + + L+ D ++ A++D K Sbjct: 211 DDHDMQRVLEFLKADPVVDALYDCK 235 Score = 41.1 bits (92), Expect = 0.056 Identities = 18/44 (40%), Positives = 30/44 (68%), Gaps = 2/44 (4%) Query: 393 DDVETF--LLKHGENIVDMLGGEIDRIELKLRKKFPQIRHCDLE 434 DD E + +GE++V+ LG E+DR+E +++K P I+H D+E Sbjct: 246 DDTELIRVMSNYGEDVVEALGYEVDRLESEIQKIVPGIKHVDIE 289 Score = 40.3 bits (90), Expect = 0.097 Identities = 19/47 (40%), Positives = 26/47 (55%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLI 150 S R V TA+ N F K W T SH + +E +HS+AD NQ++ Sbjct: 30 SHRAVNTALWCNFLVFSLKFGVWLSTSSHVMLAELVHSVADFANQVL 76 >UniRef50_Q2JCE5 Cluster: Cation diffusion facilitator family transporter; n=14; Actinobacteria (class)|Rep: Cation diffusion facilitator family transporter - Frankia sp. (strain CcI3) Length = 341 Score = 118 bits (283), Expect = 4e-25 Identities = 75/264 (28%), Positives = 131/264 (49%), Gaps = 3/264 (1%) Query: 100 LKTRSG-RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKS 158 + T+ G + V+ A+ N L K A+ T S S+ +E IHS+AD+ NQ +L G +S Sbjct: 1 MSTQGGTKAVMAALAANLGIALAKFVAFLVTQSSSMLAESIHSVADSGNQGLLLLGQKRS 60 Query: 159 VQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLG 218 VQ D +HP+GY RY++ + G+ +F +G S Y GV + P L A VL Sbjct: 61 VQPPDEEHPFGYGRARYIAGFLVGIVLFSLGGLFSVYEGVEKLRHPHELESGLVAVVVLL 120 Query: 219 GAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASC 278 AV+ E + A+ +K + + S + ++ + P + +VLLED AA G+I A Sbjct: 121 IAVLLESYSFATAMRESKK--TKGDRSWWRFIREARAPELPIVLLEDLAAELGLIFALLG 178 Query: 279 MAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDF 338 + ++ +P+ D G++ +G +L VA + G LVG + + I L Sbjct: 179 VGLTLALDDPIWDGAGTLAIGVLLLIVAVIVATEAYGMLVGEAAAPAMVATIRRTLAAAP 238 Query: 339 MIRAIHDVKGIDIGSNLIRYKAEV 362 + + ++ + +G + + A++ Sbjct: 239 GVATVIHLRTLHLGPDELLVAAKI 262 >UniRef50_Q825J3 Cluster: Putative transport protein; n=4; Streptomyces|Rep: Putative transport protein - Streptomyces avermitilis Length = 356 Score = 117 bits (281), Expect = 7e-25 Identities = 82/258 (31%), Positives = 130/258 (50%), Gaps = 9/258 (3%) Query: 108 VLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHP 167 VL A+G N + K GS +L SE HS+AD++N++ L + +S + AD HP Sbjct: 45 VLVALGANLVIAVAKAVGGLLAGSPALLSEAAHSVADSLNEVFLLAALRRSRRPADQRHP 104 Query: 168 YGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILD-PQPLHDFYWA-YFVLGGAVVSEG 225 +GY R+ SL++ VGIF +G SF+ G+ + + H Y A VLG A+++EG Sbjct: 105 FGYGKERFFWSLLAAVGIFVMGGCFSFFQGIEALRSGAEESHSGYVAGLIVLGVALLAEG 164 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 A+L+ AL +R A L DP++ V+ ED AV GV +A MA+ T Sbjct: 165 ASLLRALHQVRGQRGSAAEGL-------RDPALRTVVAEDGTAVLGVTLAMIGMALHMVT 217 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHD 345 G + +A S+ +G +L VA + L+G++ E I ++LE I ++ Sbjct: 218 GQVVWEAAASMGIGALLVYVAYRLGRDARDQLIGQAADPELSGRIRALLEAQPEIDSVES 277 Query: 346 VKGIDIGSNLIRYKAEVD 363 + + +G + A VD Sbjct: 278 LLTMQLGLHSTLVAARVD 295 >UniRef50_A4J438 Cluster: Cation diffusion facilitator family transporter; n=1; Desulfotomaculum reducens MI-1|Rep: Cation diffusion facilitator family transporter - Desulfotomaculum reducens MI-1 Length = 321 Score = 116 bits (278), Expect = 2e-24 Identities = 75/257 (29%), Positives = 129/257 (50%), Gaps = 7/257 (2%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMAD 163 S + A+ NG L KL +GS S+ +E HS+ D N L GI +S + D Sbjct: 5 SESAIKAALLANGVIALMKLVGAILSGSASMMAEFKHSVGDWANGFFLLIGIRQSQRPID 64 Query: 164 PDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVS 223 + +G+ + S ++ +G+ +G LS Y G+ I+ P+ L ++ +++ Sbjct: 65 DRYQFGHGKRLFFWSFVASLGMLFIGGALSIYGGIQKIIHPEHLEYISLNLIIIVVSILF 124 Query: 224 EGATLMVALSAIRK--GAREANMSLYEYV---MRSSDPSVNVVLLEDTAAVAGVIVAASC 278 E ++ +A+ AI G M +Y V + + P+ + LED+AA+ G+I+A Sbjct: 125 EIYSMTMAIKAIMHEVGEPARGMGMYFKVIPALTKATPATRFIFLEDSAALIGLIIAGLA 184 Query: 279 MAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEI-NSVLERD 337 + +S TGN L D + SI++G IL + NV A++G S E + E+ N VL D Sbjct: 185 IILSVVTGNVLFDGMASIIIGVILLLIGLATAKENVAAILGESADPELVQEMGNYVLTLD 244 Query: 338 FMIRAIHDVKGIDIGSN 354 ++ +H V+ + IG+N Sbjct: 245 -GVKDVHSVRSMSIGAN 260 >UniRef50_Q3IUM9 Cluster: Transporter 37; n=1; Natronomonas pharaonis DSM 2160|Rep: Transporter 37 - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 308 Score = 115 bits (276), Expect = 3e-24 Identities = 76/266 (28%), Positives = 126/266 (47%), Gaps = 1/266 (0%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 VV+ ++ + + K AW TG+ S+ S+ +SL+D NQL+ G S A H Sbjct: 7 VVVVSLVASAAIAVAKFIAWLATGNASMLSQVYYSLSDVGNQLLFLLGFRLSDAGASRKH 66 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGA 226 P+G +YV + + + +F V + G I P D Y VLG A++ E A Sbjct: 67 PFGRGKEQYVFAFVVTMLLFGVTGYAAVREGYETIGTPARDVDVTINYIVLGVALLFESA 126 Query: 227 TLMVALSAIRKGA-REANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 + A+R+ A E SL++ RS D + E+ AV GV+VA + + ++ T Sbjct: 127 AFYKSYQAVREEADTEGFRSLFDTFRRSKDAPLLTAATENLVAVVGVLVALAGVYLTDVT 186 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHD 345 GN DA+GS ++G +L VA + + G LVG + + + + + A+ D Sbjct: 187 GNTTYDAIGSAVIGLLLMSVALGLAWESRGLLVGEGVTRRERRRLLDAIAAADGVNAVVD 246 Query: 346 VKGIDIGSNLIRYKAEVDFDGRALTR 371 ++ + +G + E+DFD TR Sbjct: 247 LRTMHLGPESVLVACEIDFDNDLDTR 272 >UniRef50_Q5UZ15 Cluster: Cation efflux protein; n=1; Haloarcula marismortui|Rep: Cation efflux protein - Haloarcula marismortui (Halobacterium marismortui) Length = 323 Score = 112 bits (269), Expect = 2e-23 Identities = 80/285 (28%), Positives = 132/285 (46%), Gaps = 23/285 (8%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMAD 163 S VV+ A+ NG + K + TGS ++ SE HS++DT NQ+ L GI S + D Sbjct: 4 SKSVVIAALIANGAIAILKFFGFLLTGSAAMLSETYHSISDTGNQVFLLIGIRFSERERD 63 Query: 164 PDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGI---------------------L 202 HP+GY ++ S + V +F + S HG + Sbjct: 64 RRHPFGYGKAQFFYSFLVSVFLFGIAGWESAKHGYNQLTAGGHGGGGHAGEAVEFLFFSF 123 Query: 203 DPQPLHDFYWA-YFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMR-SSDPSVNV 260 P D W Y VL GA V E L+ A + +++ N S Y R +SD + Sbjct: 124 QPPAWLDPLWVNYTVLIGAFVFETYALIKARAEMKRQIDRNNWSGYREAFRKTSDVTTLT 183 Query: 261 VLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGR 320 L EDT A+AG+++A + + Q TGNP D + ++L+G +L G A + N L+G Sbjct: 184 ALTEDTIALAGIVIALVGLVLEQMTGNPFFDRVSALLIGIMLMGFALALAWENKRLLLGE 243 Query: 321 SIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFD 365 S+P ++ + ++ ++ + + + + G N + A++ FD Sbjct: 244 SLPTDEEQRLRDIVMQNEHVDEVIGFRTVYFGPNEVIVFADLQFD 288 >UniRef50_Q5FU46 Cluster: Cation efflux system protein; n=1; Gluconobacter oxydans|Rep: Cation efflux system protein - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 320 Score = 94.7 bits (225), Expect = 4e-18 Identities = 69/230 (30%), Positives = 109/230 (47%), Gaps = 14/230 (6%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMAD 163 S +VV A+G+N K A TGS ++ +E +HS D NQL+L G+ ++ A Sbjct: 6 STKVVFIALGVNLAIACVKGVAALLTGSAAMLAETVHSFVDCGNQLLLLVGMKRAAAPAT 65 Query: 164 PDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPL-------HDF--YWA- 213 +HP G+ Y +L+ +F G S + G + P + H F +W Sbjct: 66 KEHPLGHHRELYFWTLVVAGALFIGGGVASLHEGWEKVWHPAAMDQVRVLGHVFPGWWLN 125 Query: 214 YFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVI 273 +LG + EG + A+ ++ G SL+ + RS+DP + VVL ED AA+ + Sbjct: 126 VAILGISGSMEGYGFLAAMKSLPSG----KGSLWTMIRRSTDPGLFVVLFEDGAALVSLT 181 Query: 274 VAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIP 323 +A +S TG + D + S+L+G +L VA + LVG S P Sbjct: 182 IALVFTVLSVVTGWHVLDGVASLLIGVVLVIVAVLLTNETRSLLVGESSP 231 >UniRef50_Q838Z8 Cluster: Cation efflux family protein; n=4; Lactobacillales|Rep: Cation efflux family protein - Enterococcus faecalis (Streptococcus faecalis) Length = 311 Score = 92.7 bits (220), Expect = 2e-17 Identities = 69/267 (25%), Positives = 126/267 (47%), Gaps = 8/267 (2%) Query: 101 KTRSGR-VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 K SG V+ A+ N + K + +GS ++ +E IHS+ D NQ++L +G ++ Sbjct: 4 KKSSGMFAVIAALIANILVAISKFVGFALSGSTAMMNESIHSVVDCSNQVLLLFGNKRAS 63 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLG- 218 + H +G +Y S I +F G L + +L P H+ V+G Sbjct: 64 RGQSALHQFGEGRAKYFFSTIVATMLFFGGGALGVMEAIQKLLHPS--HEVENVAIVIGI 121 Query: 219 --GAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAA 276 ++ EG++L VA+ I++ E +SL +++ S + ++ ED AV G+ +A Sbjct: 122 LIFGLLVEGSSLRVAMKEIKELNTE-KLSLLKFLRESRHSEILIIFTEDFCAVIGLCLAL 180 Query: 277 SCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLER 336 ++ TG DA+ +L+G +L A F+ ++G S+ L +I + +R Sbjct: 181 VGTLLTMVTGIAAFDAISGLLIGLLLMCAAIFLAKEFYSLIIGESVTATDLAKIKTAFDR 240 Query: 337 DFMIRAIHDVKGIDIGSNLIRYKAEVD 363 + + I DVK + +G I A++D Sbjct: 241 ADVEKLI-DVKTVHLGPTEILVAAKID 266 >UniRef50_A1A1Q0 Cluster: Cation transporter; n=3; Bifidobacterium|Rep: Cation transporter - Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083) Length = 341 Score = 90.6 bits (215), Expect = 7e-17 Identities = 70/265 (26%), Positives = 126/265 (47%), Gaps = 15/265 (5%) Query: 79 LRDYRREMSHTRSKDNVEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSEC 138 + + R + + +N+ EV G V A+G N + KL A F+TGS ++ SE Sbjct: 1 MSESRDPAGDSTTTNNMGEVREAEHQGAAVKAALGANIGVAIAKLLAAFFTGSSAMLSES 60 Query: 139 IHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGV 198 +HS+AD N+++L G S + D DHP+G +Y++S + +F VG S V Sbjct: 61 VHSIADCSNEIVLMVGGRFSKRKTDGDHPFGLYRAKYLASFVVATLLFFVGGFFSTSEAV 120 Query: 199 TGIL----DPQPLHD-----FYWAYFVLGGAVVSEGATLMVALSAIRKGAREAN---MSL 246 ++ DP L D A+ V+ + EG L ++ + N M + Sbjct: 121 KKLVAISADP-ALRDVNRMELLVAFIVVVISACLEGFGLHQSIKEANERMERTNTPRMGV 179 Query: 247 YEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVA 306 + + R+ + V++EDT A+ G+ A + ++ + + DALG ++VG +L V Sbjct: 180 FRFWRRTKSAELASVIMEDTLALIGLAFAGLGIGLAIALDDEVFDALGGLMVGLVL-IVG 238 Query: 307 SFIILSNVGA-LVGRSIPHEQLDEI 330 S ++ G+ L+G ++ + +I Sbjct: 239 SLLLAFKSGSLLIGEAVDSDTRGKI 263 >UniRef50_A5ZXZ3 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 391 Score = 83.4 bits (197), Expect = 1e-14 Identities = 71/257 (27%), Positives = 120/257 (46%), Gaps = 19/257 (7%) Query: 112 IGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYT 171 IG+N F K A +GS ++ ++ ++L+D + +I G S Q DP+HP+G+ Sbjct: 36 IGLNILLFFGKWLAGTISGSIAITADAFNNLSDAGSSIITLIGFRLSGQEPDPEHPFGHG 95 Query: 172 NMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVA 231 M Y+S L+ V I +G L + + P+P+ + V G + A+++V Sbjct: 96 RMEYISGLLVSVAILVMGFEL-IGSSIGKLRSPEPIES---SALVFGILI----ASILVK 147 Query: 232 LSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPD 291 L N SL + + ++ + +V L DT A V++A IS+YTG L Sbjct: 148 LYMFFY-----NHSLSKKIESAAMKATSVDSLSDTVATTLVLIAT---LISKYTGLLLDG 199 Query: 292 ALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDI 351 G ILVG + + + L+G+ E +DE+ ++ M+ +HD+ D Sbjct: 200 WFG-ILVGLFILYTGGSTLKETIDLLLGQPPKQEFIDEVKEIVLGHSMVHGVHDLIVHDY 258 Query: 352 GSN--LIRYKAEVDFDG 366 G +I AEVD +G Sbjct: 259 GPGRVMISLHAEVDVNG 275 >UniRef50_Q5UX98 Cluster: Cation efflux system protein; n=3; Halobacteriaceae|Rep: Cation efflux system protein - Haloarcula marismortui (Halobacterium marismortui) Length = 304 Score = 80.6 bits (190), Expect = 7e-14 Identities = 81/303 (26%), Positives = 135/303 (44%), Gaps = 37/303 (12%) Query: 101 KTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQ 160 +T RV L +G+N L K W TGS ++ SE ++S ADT L++ G++ + + Sbjct: 4 RTTLRRVGLLVLGVNLLLVLLKAGVWLTTGSFAVQSEAVNSAADTAYSLVIVAGLYLTTR 63 Query: 161 MADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGA 220 D +HP+G+ + SL GIF G G ++ T +L G Sbjct: 64 PPDFEHPHGHERIEPFVSLFVAAGIFAAG-GFVLWNAGTALLT--------------GNI 108 Query: 221 VVSEG--ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASC 278 V++G A L++A SA+ K A LY Y +R+ + L+ I+ A Sbjct: 109 SVTQGPAAVLVLAFSAVAKYA------LYRYCLRAGTDRNSPALIATAKDNRNDILTAGA 162 Query: 279 MAIS---QYTGNPLPDALGSILV--GTILGGVASFIILSNVGALVGRSIPHEQLDEINSV 333 + G P+ D L +++V G I G+ ++ NV LVG + P + EI Sbjct: 163 ALVGVGGAMAGYPIADPLAALVVAIGIIYTGIE--VVQENVTYLVGGAPPEDLRREILRR 220 Query: 334 LERDFMIRAIHDVKGIDIGSNL-IRYKAEVDFDGRALTRSYLEKHDL-NALLEDMKKIDT 391 + HDV +G + + EV+ D LT E HD+ A+++ ++++ Sbjct: 221 ALDHPKVSGAHDVIAHYVGPEIDVSLHIEVEGD---LT--LFEAHDIETAVIKSIEELPE 275 Query: 392 IDD 394 +DD Sbjct: 276 VDD 278 >UniRef50_A5FSC2 Cluster: Cation diffusion facilitator family transporter precursor; n=3; Dehalococcoides|Rep: Cation diffusion facilitator family transporter precursor - Dehalococcoides sp. BAV1 Length = 311 Score = 80.2 bits (189), Expect = 1e-13 Identities = 71/255 (27%), Positives = 116/255 (45%), Gaps = 17/255 (6%) Query: 100 LKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 + TR R +I N K F TGS S+ +E IHS D + +I +G+ S Sbjct: 1 MATRKTRAASFSIASNSTLIAMKTVVGFVTGSVSILAEAIHSTLDLIAAVIAFFGVKASD 60 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGG 219 + AD DHPYG+ VS + V IF V + Y V ++ W ++G Sbjct: 61 KPADIDHPYGHGKWENVSGTVEAVLIF-VAAIWIIYEAVNRLIGGSAPEMLEWGVVIMGI 119 Query: 220 AVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCM 279 +VV A +V+ ++K A E + V +D S L D AGV+V + Sbjct: 120 SVV---ANTLVS-RYLKKIAHET-----DSVALEADAS---HLTTDVITSAGVLVG---L 164 Query: 280 AISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVL-ERDF 338 + + TG + D + ++LV ++ A I+ + GALV +P E+++ I S++ E Sbjct: 165 VLVKITGWVILDPIVALLVALLIIKAAWDILNKSFGALVDARLPKEEVEAITSLINEHTS 224 Query: 339 MIRAIHDVKGIDIGS 353 + H+++ GS Sbjct: 225 KLVEFHNLRTRKAGS 239 >UniRef50_Q92AW3 Cluster: Lin1805 protein; n=17; Bacillales|Rep: Lin1805 protein - Listeria innocua Length = 321 Score = 79.4 bits (187), Expect = 2e-13 Identities = 59/231 (25%), Positives = 105/231 (45%), Gaps = 6/231 (2%) Query: 96 EEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGI 155 E +GL + LTA +N + K +F+TG+ ++F+E +HSL D NQ + G Sbjct: 3 ELLGLLKEGNKSALTAALVNTIVSIIKGVTYFFTGNIAMFAETLHSLGDAANQFFVFIGS 62 Query: 156 HKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYF 215 S + P+G+ M + L+ V + + + + G I+DP F Sbjct: 63 ALSKKRPTKRFPHGFGRMVNL-VLLGAVIVVGIMAFETIREGFAHIIDPTSSTGFLINLV 121 Query: 216 VLGGAVVSEGATLMVALSAIRK--GAREANMSLYE---YVMRSSDPSVNVVLLEDTAAVA 270 VL + E + L+ A+ I G +SL++ + + + +V LED+ A Sbjct: 122 VLLLCTILEFSVLVKAMHEIAHDVGLESKGLSLFKDSILNLGKAKAATKLVFLEDSVATG 181 Query: 271 GVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRS 321 G ++A + IS YT + + S+L+G ++ V + L N ++G S Sbjct: 182 GGLLAMIAVIISHYTPFHQAEGIASMLIGVMMFIVVGKVFLDNAAGVIGES 232 >UniRef50_A0DMX0 Cluster: Chromosome undetermined scaffold_57, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_57, whole genome shotgun sequence - Paramecium tetraurelia Length = 489 Score = 76.2 bits (179), Expect = 2e-12 Identities = 72/331 (21%), Positives = 142/331 (42%), Gaps = 23/331 (6%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K A++ T + ++E S+ D N +IL + + PYG ++++ +LI Sbjct: 56 KFAAYYITNQQTFWAELTRSMIDASNHVILFATQIILIMGPNKQFPYGIEKVKHLVALIP 115 Query: 182 GVGIFCVGSGLSFYHGVTGILD----PQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRK 237 G+ +S Y I + +H W L ++S G V IR Sbjct: 116 SALFLYFGASIS-YESFLNIYNYGHYVGEIHSNAWG---LALYLLSIGIETSVVFKNIRD 171 Query: 238 GA-----REANMSLYEY---VMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPL 289 E L++ V + DP + +L E+ + ++ A + Sbjct: 172 AQAVDSNEEIKKGLFKQFLSVFQKKDPVLQAILYENAITLGSTLIPLLSSAFTLIYPTHA 231 Query: 290 PDALGSILVGTILGGVASFIILSNVGALVG-RSIPHEQLDEINSVLERDFMIRAIHDVKG 348 + +GS+ +G I +A + N+ +L+G +SI ++ +I +++++ + I + K Sbjct: 232 FEIVGSLAIGLIQLQLAYHLSAKNLSSLMGEQSISDFEVKKILEIIKQNQYVEKIQNEKA 291 Query: 349 IDIGSNLIRYKAEVDFDGRALTR----SYLEKHDLNALLEDMKKIDTIDDVETFLLKHGE 404 + +GS R+ AE+ F+ + + + YLE+ D E + D + ++ L + E Sbjct: 292 VMLGSRKFRFSAEITFNIKQINQDTESKYLERFDKVIYSESYR--DREEYLQELLREIQE 349 Query: 405 NIVDMLGGEIDRIELKLRKKFPQIRHCDLEI 435 ++ L +I +IE +R +FP H D EI Sbjct: 350 YVLASLHIQIQKIESAIRNEFPNCIHLDFEI 380 >UniRef50_UPI00006CBFC4 Cluster: cation efflux family protein; n=1; Tetrahymena thermophila SB210|Rep: cation efflux family protein - Tetrahymena thermophila SB210 Length = 585 Score = 74.1 bits (174), Expect = 6e-12 Identities = 77/387 (19%), Positives = 173/387 (44%), Gaps = 25/387 (6%) Query: 70 QDVFTVKRRLRDYRREMSHTRSKDNVEEVGLKTRSG--RVV--LTAIGINGCNFLFKLCA 125 ++ F +++L ++ +++ +T D ++ K + ++ + +IGI G LF+ Sbjct: 79 EEKFDPEQKLAEFEKKVKNTNLNDTRKKFRFKYQQTIYNILPNMMSIGI-GLQLLFQFYL 137 Query: 126 WFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYV-----SSLI 180 +F + +E S D VN L+L + + V+ + +P G N++ + SSL Sbjct: 138 YFKRSVGTFLAELCRSSIDAVNHLVLYFANYIDVKPSKR-YPQGLENIKQLIVLIPSSLF 196 Query: 181 SGVGIFCVGSGLSFYHGVTGILDPQPLHDF----YWAYFVLGGAVVSEGATLMVALSAIR 236 G + + S + Y + Q + + Y A F + +V++ + + I Sbjct: 197 VSFGAYTIYSAFTEYLAAGPAVAAQSDNIYSILLYLASFCIEISVIAYNIRDSLKMQNIN 256 Query: 237 KGAR-EANMSLYEYV---MRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDA 292 + +SL++ + + DP + +L E+ + + V + + LP+ Sbjct: 257 STQQTNQKLSLFQIMKTLVAKKDPLLQAILYENMITLMSMSVPLMVGISNMIIPSNLPEF 316 Query: 293 LGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIG 352 +G I++G+I + + ++G+S+ E +++I++ + ++ +++I D KGI G Sbjct: 317 IGQIVIGSIQLLLGQRLFKEVASTILGKSVDEETMNDIHNEIMKNPYVKSIRDEKGIMSG 376 Query: 353 SNLIRYKAEVDFDGRALTRSYLEKH----DLNALLEDMKKIDTIDDVETFLLKHGENIVD 408 S +Y A V++D L +E + D +D K D +++E + ++ Sbjct: 377 SVRFKYYAIVEYDFEQLNEDAMEDYRQMSDYIIYSQDYK--DRQEELEELMESFPIRLLK 434 Query: 409 MLGGEIDRIELKLRKKFPQIRHCDLEI 435 + + I ++ K+PQ + DL I Sbjct: 435 EVKRQEQLILESIKIKYPQCDYLDLNI 461 >UniRef50_A0KRS9 Cluster: Cation diffusion facilitator family transporter; n=10; Alteromonadales|Rep: Cation diffusion facilitator family transporter - Shewanella sp. (strain ANA-3) Length = 299 Score = 71.7 bits (168), Expect = 3e-11 Identities = 62/246 (25%), Positives = 112/246 (45%), Gaps = 20/246 (8%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 L KL AW Y+GS S+ + S AD + +I I ++ AD DH YG+ ++SL Sbjct: 27 LIKLLAWLYSGSASMLASLTDSFADALASIINFIAIRYAIVPADHDHRYGHGKAEPLASL 86 Query: 180 ISGVGIFCVGSG-LSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKG 238 F +GS L ++G +L+P P+ + LG V L +AL ++K Sbjct: 87 AQSA--FIMGSAFLLLFYGGERLLNPAPVE-----HATLGVVVSVVAIVLTLALVMLQKR 139 Query: 239 AREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILV 298 A A S+ + + + + G ++ A + +SQY G D L ++L+ Sbjct: 140 ALAAT--------NSTVVEADSLHYKSDLFLNGAVLLA--LVLSQY-GWWWADGLFAVLI 188 Query: 299 GTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNL-IR 357 +G A + ++ AL+ R + + I + + D ++ +HD++ G + I+ Sbjct: 189 ACYIGQQAFDLGYRSIQALLDRELDEDTRQRIKQIAKEDSRVQGLHDLRTRQAGKTIFIQ 248 Query: 358 YKAEVD 363 + E+D Sbjct: 249 FHLELD 254 >UniRef50_Q3IQA7 Cluster: Transporter 38; n=1; Natronomonas pharaonis DSM 2160|Rep: Transporter 38 - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 323 Score = 65.7 bits (153), Expect = 2e-09 Identities = 86/316 (27%), Positives = 136/316 (43%), Gaps = 39/316 (12%) Query: 96 EEVGLKT-----RSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTV-NQL 149 EE GL+T R R L + N L + GS +L ++ HS+AD V + + Sbjct: 7 EEAGLETETARRRFSRASLVNVAGNAVKILVEGAVGLAFGSVALLADAAHSVADLVASAV 66 Query: 150 ILAYGIHKSVQMADPD--HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPL 207 +L +G +SV DPD HP+G+ + +++L G I +G L FY TG++ P Sbjct: 67 VLVWG--RSVY-TDPDENHPHGHQRVEPLAALFVGSLIVLLGLNL-FYESATGLV-AGPE 121 Query: 208 HDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEY---VMRSSDPSVNVVLLE 264 F+ +L GA++ A + + LY Y + S S L Sbjct: 122 VQFHP---LLVGALLFAMADMYL---------------LYWYTTHINESVGSSALEALAI 163 Query: 265 DTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPH 324 D +AA C I + G PL DA+ LV ++ I NV LVG S Sbjct: 164 DCRNDIYTTIAALCGVIGVFFGYPLFDAVAGGLVSVLVVYQGFEISRENVSYLVGASPSD 223 Query: 325 EQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLNA-LL 383 +Q + L + HDV G++ I +A V+ DG + +E HD+ L+ Sbjct: 224 QQRQRVVETLTDHPAVHGAHDVAVFYDGTD-IEVEAHVEVDGEL---TLVEAHDIETELV 279 Query: 384 EDMKKIDTIDDVETFL 399 ++ ++++ DV L Sbjct: 280 SALRSLESVGDVHLHL 295 >UniRef50_A6NR09 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 392 Score = 64.1 bits (149), Expect = 7e-09 Identities = 74/306 (24%), Positives = 135/306 (44%), Gaps = 30/306 (9%) Query: 94 NVEEVGLKTRSGRVVLTAIGINGCNFLF---KLCAWFYTGSHSLFSECIHSLADTVNQLI 150 NV++ ++ R G + A+GI N L K+ A TGS ++ ++ ++L D + ++ Sbjct: 15 NVQDPQVRQRYG-TLSGAVGIF-LNLLLSAGKMIAGLITGSIAITADAFNNLTDAGSSVV 72 Query: 151 LAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDF 210 G + + AD DHP+G+ + Y+S L V I VG L+ V I+ P+P+ +F Sbjct: 73 TLVGFRMAGKQADDDHPFGHGRIEYLSGLAVSVVILLVGLELA-KSSVEKIIHPEPV-EF 130 Query: 211 YWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVA 270 W A +++A ++ N SL + ++ + L D A + Sbjct: 131 SWL-----------SAGILIAAICVKLWMSYFNRSLSRRIGSAAMAATATDSLSDAVATS 179 Query: 271 GVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEI 330 V+++A I ++TG + DA ILV + + L+G+S E + +I Sbjct: 180 AVLLSA---IIGKFTGVNI-DAWAGILVALFILRAGWGAAKDTLNPLLGQSPDPELVRDI 235 Query: 331 NSVLERDFMIRAIHD--VKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHD-LNALLEDMK 387 + + IHD + G +++ AEV +E HD ++A+ ++K Sbjct: 236 ERTVLAHPQVVGIHDMIIHDYGPGRSMMSLHAEVPAGS-----DIMEVHDEIDAIERELK 290 Query: 388 KIDTID 393 ID Sbjct: 291 AKYRID 296 >UniRef50_A6DS63 Cluster: MMT1 protein; n=1; Lentisphaera araneosa HTCC2155|Rep: MMT1 protein - Lentisphaera araneosa HTCC2155 Length = 339 Score = 64.1 bits (149), Expect = 7e-09 Identities = 65/263 (24%), Positives = 111/263 (42%), Gaps = 21/263 (7%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K AW +TGS +L S S D + ++ + S++ AD DH +G+ ++++ Sbjct: 62 KFIAWNFTGSATLLSSLTDSSLDFLASMLSFAVLTYSLKPADEDHRFGHGKAEGLAAVFQ 121 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGARE 241 + G + + GV + DP P+ +G + S TL AL ++ Sbjct: 122 SGIVLIAGLSVLYQAGVR-LFDPAPMEK---TGLAIGIMLFSLALTL--ALITYQQKVYN 175 Query: 242 ANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTI 301 SL R+ + D A AG IVA I Y G DA+G I+V + Sbjct: 176 ITGSLVVKADRAH-------FVSDILANAGAIVA----LILAYVGVSYADAIGGIVVALL 224 Query: 302 LGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAE 361 + A + + L+ +P E + E ++E + I HDV+ G L ++ Sbjct: 225 IVKAAWEVFEHALEMLLDHELPQEDVKEFEQMIEDERNILGYHDVRTRRSGKTLF-FQVH 283 Query: 362 VDFDGRALTRSYLEKHDLNALLE 384 ++F+ +AL E HD+ +E Sbjct: 284 LEFEDQALLS---EAHDIADRIE 303 >UniRef50_O28143 Cluster: Conserved hypothetical transmembrane protein; n=1; Archaeoglobus fulgidus|Rep: Conserved hypothetical transmembrane protein - Archaeoglobus fulgidus Length = 283 Score = 63.3 bits (147), Expect = 1e-08 Identities = 63/281 (22%), Positives = 115/281 (40%), Gaps = 20/281 (7%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 KL A+F +G ++ ++ HS+ D LIL + + AD HP+G+ R V+SL Sbjct: 15 KLYAYFLSGFTAILADAFHSVIDITMILILLLSERYAEKEADYQHPFGHEMARNVASLAV 74 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGARE 241 GVG G+ +L P Y + A+ +E A L + + A AR Sbjct: 75 GVGFITFMFFELMKEGLLKVLHPAS------GYSNVEVALGAEVAVLALLVIAALISARR 128 Query: 242 ANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTI 301 + + ++ S + S++ + AA+ GV + + G P+ D + +I + I Sbjct: 129 SGILNRTLLVESLNDSLSTL-----AAIVGVGLV--------WAGYPIFDGIATIAIAFI 175 Query: 302 LGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAE 361 + + ++ N L+G S + + ++ +HD+ G+ G N + Sbjct: 176 IFYNSFRLVRDNARLLIGMSPSEDFYRSVEDACLEIERVKGVHDMVGVYTGENSVHLDLH 235 Query: 362 VDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDVETFLLKH 402 V DG A+T +K + M K + + H Sbjct: 236 VTVDG-AMTIEEADKLSVEIAEAIMAKHPEVKHISVHFCPH 275 >UniRef50_A1THH9 Cluster: Cation diffusion facilitator family transporter precursor; n=1; Mycobacterium vanbaalenii PYR-1|Rep: Cation diffusion facilitator family transporter precursor - Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) Length = 300 Score = 62.5 bits (145), Expect = 2e-08 Identities = 52/231 (22%), Positives = 105/231 (45%), Gaps = 16/231 (6%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R +L ++ K A TGS S+ + S + V ++ + + + + D D Sbjct: 16 RFMLLSLAAAIVTMALKAGAAVITGSVGFLSDALESGVNLVAAVVALWALRVAARPRDAD 75 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 H +G+ Y+S+L+ G IF + + + V ++ P PL L + + G Sbjct: 76 HHFGHGKAEYLSALVEGAMIFVAATAI-IWSAVERLMSPAPL---VQPGVGLALSTAAAG 131 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 L+V ++ +R G R +++L + L+ D AGVIV S +A++ + Sbjct: 132 VNLVVGVTLLRMGRRHRSVTLV---------ADGKHLMTDVWTSAGVIVGISLVALTDW- 181 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLER 336 PL D + ++ VG + ++ ++ +L+ ++P + +N+VL+R Sbjct: 182 -YPL-DPIVALAVGVNILWTGYRLLRGSMSSLLSAALPEQDHAAVNAVLDR 230 >UniRef50_P74068 Cluster: Uncharacterized transporter sll1263; n=2; Chroococcales|Rep: Uncharacterized transporter sll1263 - Synechocystis sp. (strain PCC 6803) Length = 310 Score = 62.1 bits (144), Expect = 3e-08 Identities = 55/211 (26%), Positives = 92/211 (43%), Gaps = 16/211 (7%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 KL A+ TGS L S+ + S + + ++ + + + AD +HP+G++ Y SS + Sbjct: 24 KLGAYAITGSVGLLSDALESTVNLASAIVAFWALSLAATPADSEHPFGHSKAEYFSSGLE 83 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGARE 241 G IF G+ Y V +L P+PL + A G VA R G R Sbjct: 84 GAFIFVAALGIG-YSAVERLLSPRPLDQNALGIALAIAATALNGT---VAWILWRAGKR- 138 Query: 242 ANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTI 301 L +R+ L+ D GV+VA + + + TG D L ++ VG Sbjct: 139 ----LNSIALRADSQH----LMTDVWTSVGVVVAVALIFV---TGWEWLDPLIALGVGFN 187 Query: 302 LGGVASFIILSNVGALVGRSIPHEQLDEINS 332 + + ++ + +L+ +S+P QL I S Sbjct: 188 VLWTGTHLLRETISSLMDQSLPPAQLQAITS 218 >UniRef50_A4EAI9 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 393 Score = 60.5 bits (140), Expect = 9e-08 Identities = 70/300 (23%), Positives = 127/300 (42%), Gaps = 22/300 (7%) Query: 91 SKDNVEEVGLKTRSGRVV-LTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQL 149 S+ + +T +G L IG+N L K A GS SL ++ ++L+D + + Sbjct: 15 SESEPVDTSCRTNAGFAASLICIGLNITLCLAKGIAGLLAGSVSLIADAFNNLSDASSNI 74 Query: 150 ILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHD 209 + G + + AD HPYG+ Y++ L V + VG L VT I+ P P Sbjct: 75 VSLLGFRLASRPADEGHPYGHGRYEYLAGLFVAVLVCAVGINL-ILESVTKIIKPSPT-- 131 Query: 210 FYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAV 269 AY + A ++ + + ++A + N E ++ ++ S N V+ Sbjct: 132 ---AYTFISLAALATSMLVKLWMAAFNRTL--GNRIDSETLIATAQDSKNDVI------T 180 Query: 270 AGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDE 329 +G ++AA+ ISQ TG L D + VG + ++ + + L+G++ + + Sbjct: 181 SGSVLAAA--LISQATGFDL-DGWAGLGVGIFICISGMGLVRNAISPLLGQAPDPKLVQA 237 Query: 330 INSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHD-LNALLEDMKK 388 I + + HD+ D G A V+ G E H+ L+ + D+K+ Sbjct: 238 IRDKIMSYPQVLGTHDLMVHDYGPGRQFASAHVEMPGEG---DAFEHHEILDTIEHDIKR 294 >UniRef50_Q2SCG7 Cluster: Predicted Co/Zn/Cd cation transporters; n=1; Hahella chejuensis KCTC 2396|Rep: Predicted Co/Zn/Cd cation transporters - Hahella chejuensis (strain KCTC 2396) Length = 383 Score = 60.1 bits (139), Expect = 1e-07 Identities = 59/257 (22%), Positives = 109/257 (42%), Gaps = 17/257 (6%) Query: 101 KTRSG-RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 KTR+ RV L + ++ L K+ SH+L ++ IHS D +++ S Sbjct: 9 KTRAAHRVTLIGMILDIALGLLKIIVGVLAQSHALVADGIHSFTDAGTDILVIVITRYSH 68 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGG 219 Q D +HPYG+ + +++ G + V +G Y + + + W + Sbjct: 69 QKPDREHPYGHGKFETLGTVVLGSMLIAV-AGAMAYDSILRLWEKDAQVAPGWPALLAAS 127 Query: 220 AVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCM 279 ++ + I K R + + RS S VVL+ A+ GVI Sbjct: 128 LSIAGKEWIYRYTLDIGKKLRSDLIIANAWHSRSDALSSVVVLI----ALLGVI------ 177 Query: 280 AISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFM 339 G P DAL +I+V ++G + + +V LV ++P +Q+ I + Sbjct: 178 -----AGFPWVDALAAIIVAILIGKIGIELAGKSVKELVETALPEDQVHAIRELALSVEG 232 Query: 340 IRAIHDVKGIDIGSNLI 356 +R +HD++G +G +++ Sbjct: 233 VRGVHDLRGRYVGPDIV 249 >UniRef50_A6VZC2 Cluster: Cation diffusion facilitator family transporter; n=2; Marinomonas|Rep: Cation diffusion facilitator family transporter - Marinomonas sp. MWYL1 Length = 388 Score = 59.7 bits (138), Expect = 1e-07 Identities = 54/231 (23%), Positives = 104/231 (45%), Gaps = 25/231 (10%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 L K+ A +++ S +L ++ IHSL+D V + + + S Q D +HPYG+ ++++ Sbjct: 27 LAKIVAGYFSQSQALIADGIHSLSDLVTDVFVYFASANSRQGPDENHPYGHLRFETLTTV 86 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 G+ + V G++ Y +T P F W G +VA AI++ Sbjct: 87 FLGIVLIVVALGIA-YESITA---PASQAQFTW-----------YGLAALVATIAIKE-- 129 Query: 240 REANMSLYEYVMRSSDPSVNVVLLED---TAAVAGVIVAASCMAISQYTGNPLPDALGSI 296 +++ Y ++ D + +L+ + + + A VA I Y G D + SI Sbjct: 130 -----AIFHYTKKAGDKIGSKMLVANAWHSRSDALSSVAVLIGLIGVYFGYGWADMVASI 184 Query: 297 LVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVK 347 +V ++G +A ++ N+ LV + + + +I + A HDV+ Sbjct: 185 VVALLIGKMAVSMVWENLAELVDTAPDPKLIAQIKETANSLKHVMAPHDVR 235 >UniRef50_A4E9J2 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 386 Score = 59.7 bits (138), Expect = 1e-07 Identities = 60/250 (24%), Positives = 111/250 (44%), Gaps = 20/250 (8%) Query: 129 TGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCV 188 +GS S+ ++ +++L+D + ++ G + + ADP+HPYG+ Y+S L+ + + Sbjct: 44 SGSVSIVADAMNNLSDASSNIVSVLGFKLASKPADPEHPYGHGRYEYLSGLVVAALVLLI 103 Query: 189 GSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYE 248 G L V ++ P+P+ ++ ++ V+S L +A + G R + +L+ Sbjct: 104 GVEL-VKSSVERVIHPEPVE---FSLALVAVLVLSMIVKLWMAALNQKLGDRIESETLH- 158 Query: 249 YVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASF 308 ++ S N VL G ++A C +SQ T L DA + VG +G Sbjct: 159 ---ATAQDSKNDVL------ATGAVLA--CAIVSQVTHINL-DAWVGLAVGAYIGWSGFE 206 Query: 309 IILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDGRA 368 +I V L+G++ + + I + + +HD+ D G A + A Sbjct: 207 LIQDTVSPLLGQAPDPKLVKHIRDKIMSYPGVLGVHDLMVHDYGPGRKFASAHAEMSAEA 266 Query: 369 LTRSYLEKHD 378 S LE HD Sbjct: 267 ---SPLESHD 273 >UniRef50_Q8VLX7 Cluster: CzrB protein; n=3; Thermus thermophilus|Rep: CzrB protein - Thermus thermophilus Length = 291 Score = 59.3 bits (137), Expect = 2e-07 Identities = 53/228 (23%), Positives = 107/228 (46%), Gaps = 18/228 (7%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K A+ TGS +L S+ + SL + L + + + D +HP+G+T YVS+++ Sbjct: 20 KAFAYLLTGSVALLSDALESLVNVAAALAALLALRVARKPPDQNHPFGHTKAEYVSAVLE 79 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGARE 241 GV + ++ + +L P PL LG ++++ ++A +++G R Sbjct: 80 GVLVVLAALWIA-REALPRLLHPVPLEGLGLG---LGVSLLASLLNGLLAYHLLKEGRRH 135 Query: 242 ANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTI 301 + +L ++D +L D GV++ + ++ TG + D L ++ V Sbjct: 136 RSPAL------TAD---GYHVLSDVLTSLGVVLG---VGLAGLTGLWVLDPLLALAVAGQ 183 Query: 302 LGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRA--IHDVK 347 + + I+ +VG L+ +P E+++ I + L+ RA +HD+K Sbjct: 184 ILFLGYRIVRESVGGLMDEGLPPEEVERIRAFLQERIRGRALEVHDLK 231 >UniRef50_A7AEG5 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 303 Score = 58.8 bits (136), Expect = 3e-07 Identities = 65/285 (22%), Positives = 125/285 (43%), Gaps = 17/285 (5%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 V LT N +FK A S ++ ++ +HSL+D V +I+ I+ S + D H Sbjct: 13 VTLTGSLANFLLLVFKFVAGVLGHSSAMIADAVHSLSDFVTDVIVLLFINISSKPKDEGH 72 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG- 225 YG+ +++ I G+ + CVG+GL F+ G + FY+ G + S G Sbjct: 73 DYGHGKYETLATTIIGIVLMCVGAGL-FWDGANKVF------GFYFG----GEQLESPGK 121 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 L+ A+ +I ++LY +S + + A + + Sbjct: 122 IALIAAIISILIKETLYRLTLYVGKKENSQAVIANAWHHRSDAFSSIGTTLGIGGAILLG 181 Query: 286 GN-PLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIH 344 N + D + +++V ++ VA +++ + L+ +S+P E D+I S++ +R H Sbjct: 182 DNWRVLDPIAAVIVSILIVKVAFQLVIPAINDLLEKSLPTEVEDKILSIINETPEVRNPH 241 Query: 345 DVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKI 389 ++ IG N + + DG+ +T S H+L +E ++ Sbjct: 242 NLCTRRIG-NDFAIEVHIRVDGQ-ITVS--RAHELTKEIESKLRL 282 >UniRef50_Q8Y4L4 Cluster: Lmo2423 protein; n=14; Bacillales|Rep: Lmo2423 protein - Listeria monocytogenes Length = 291 Score = 58.4 bits (135), Expect = 3e-07 Identities = 41/125 (32%), Positives = 62/125 (49%), Gaps = 7/125 (5%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 + KL F+TGS ++ SE IHS D +I + I S Q AD DHPYG+ ++ Sbjct: 19 VLKLIVGFFTGSVAVISEGIHSSMDLFASIITFFSIRISNQPADEDHPYGHGKAENIAGT 78 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALS-AIRKG 238 I + IF G + V +++P + + LG V+ GA + + +S I+K Sbjct: 79 IETLLIFVAGIWI-IVESVNKLVNPHEIR-----FPALGIMVMLFGAIVNIIVSRIIKKA 132 Query: 239 AREAN 243 A EAN Sbjct: 133 ADEAN 137 >UniRef50_Q6MQU1 Cluster: Cation efflux system protein; n=1; Bdellovibrio bacteriovorus|Rep: Cation efflux system protein - Bdellovibrio bacteriovorus Length = 345 Score = 58.4 bits (135), Expect = 3e-07 Identities = 51/219 (23%), Positives = 97/219 (44%), Gaps = 17/219 (7%) Query: 119 FLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSS 178 F K+ A+ TGS ++ S+ + S+ + + ++ + I + Q AD +HPYG+ Y SS Sbjct: 27 FAMKVFAYRLTGSTAVLSDALESIVNVIAAIVALFVIRFASQPADENHPYGHGKAEYFSS 86 Query: 179 LISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKG 238 G G+ + + V ++ +P ++GGA A + +AL K Sbjct: 87 AFEG-GMIFFAAIMIIGEAVKALIYHEPTQQLETGLLIVGGA-----ALVNLALGLYLKR 140 Query: 239 AREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILV 298 + S +++S V L D GV+V + + TG D + ++LV Sbjct: 141 VGRTHQS---DALKASGAHV----LSDVLTTVGVMVGLGLVLL---TGIQWLDPVIAVLV 190 Query: 299 GTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERD 337 G L I+ ++G L+ + P L+++ +E++ Sbjct: 191 GLQLAYAGFKIVRGSLGGLMDQQDP-ASLEQLAEAMEKN 228 >UniRef50_A6TSV8 Cluster: Cation diffusion facilitator family transporter; n=1; Alkaliphilus metalliredigens QYMF|Rep: Cation diffusion facilitator family transporter - Alkaliphilus metalliredigens QYMF Length = 296 Score = 58.4 bits (135), Expect = 3e-07 Identities = 55/238 (23%), Positives = 98/238 (41%), Gaps = 23/238 (9%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K+ GS +L ++ HS +D + L++ GI + Q AD HPYG+ ++S I Sbjct: 28 KIMVGLAAGSAALVADGFHSASDLIGTLVVMQGIKIAHQPADESHPYGHYRAETITSKIL 87 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGARE 241 + + GL Y G+ + P+ E L +AL ++ Sbjct: 88 AIILILTAMGLG-YEGLQVLRSPE--------------LSPPEMLALYIALFSV-----I 127 Query: 242 ANMSLYEYVMRSSDPSVNVVLLED---TAAVAGVIVAASCMAISQYTGNPLPDALGSILV 298 A +Y+Y +R + ++ D + A +AAS + G P+ D L +I V Sbjct: 128 AKEGIYQYNIRIGKRIKSSAIIADAWHARSDAFSSIAASIGIVGSILGYPIMDPLAAIFV 187 Query: 299 GTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLI 356 ++ I + ++ L+ + P E LD I + + +HD+K GS + Sbjct: 188 AFLILKTGVSIYVDSIKTLMDTAPPKEILDMIETAALAAEGVEDVHDIKVRQYGSKYL 245 >UniRef50_Q57891 Cluster: Uncharacterized transporter MJ0449; n=4; Euryarchaeota|Rep: Uncharacterized transporter MJ0449 - Methanococcus jannaschii Length = 283 Score = 58.4 bits (135), Expect = 3e-07 Identities = 67/291 (23%), Positives = 127/291 (43%), Gaps = 26/291 (8%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 ++L+ +G N L K+ + S SL S+ IHSL+D + +I G+ + + D H Sbjct: 8 LILSIVG-NILLGLIKIIIGYVYSSISLISDGIHSLSDVITSIIGIIGVKIASKPPDESH 66 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGA 226 PYG++ + S G+ +F + + V I+ Y G V+ A Sbjct: 67 PYGHSRFECLFSFFIGLALFFTAYEIGKF-AVERII-----------Y----GEVIEVNA 110 Query: 227 TLM-VALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 ++ VA+ +I SL+ +S + + A++ V+V + Q Sbjct: 111 IMVGVAILSIVVKELMTRYSLFVGKKLNSQVLIADAYHHRSDALSSVVVLVGLLL--QKF 168 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHD 345 G DA+ I+V ++ VA I L+N+ L GR+ P + + I + +HD Sbjct: 169 GIYYGDAIAGIIVALMIAKVAFDICLTNIDYLTGRAPPKKFFELIEKEALNVDKVIGVHD 228 Query: 346 VKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDVE 396 +K +G I + V+ S E HD+ +++ +++++++VE Sbjct: 229 IKAHYVGPR-IHVELHVEVPSNI---SAKEMHDIEVAVKN--RLESLENVE 273 >UniRef50_Q2BDX4 Cluster: Putative uncharacterized protein; n=2; Bacillus sp. NRRL B-14911|Rep: Putative uncharacterized protein - Bacillus sp. NRRL B-14911 Length = 338 Score = 58.0 bits (134), Expect = 5e-07 Identities = 66/288 (22%), Positives = 128/288 (44%), Gaps = 11/288 (3%) Query: 109 LTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPY 168 + AIG N + K A +GS ++ + +HS AD +NQ + G + + P Sbjct: 34 IAAIG-NTVLTIAKGVAAAISGSGTMLATTLHSAADALNQGFVFIGSALAEKEPTKRFPT 92 Query: 169 GYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATL 228 G+ + + L++ + + + + + + G I P+ + ++ A+ +G L Sbjct: 93 GFGRVVNLFVLVAVI-VIAIMAYETIHKGWELIQHPKESTNILLNISIMLLAIGVDGFIL 151 Query: 229 MVALSAIRKGAR-EAN-MSLYEYVMRSS---DPSVNVVLLEDTAAVAGVIVAASCMAISQ 283 + A+ I R EA S+ +++ P +V ED A G ++A + ++ Sbjct: 152 VKAMKEINHETRSEAKGFSIVTTAFKNNGLASPPTRLVFYEDLIATFGALLALVSILLAH 211 Query: 284 YTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAI 343 +TG D +G+IL+G +L G+A I N L+G + P D + +++ D + I Sbjct: 212 FTGFYFLDGVGTILIGLLLTGIAVKIGYENTIGLIGVAAPKIVEDRVANMILSDPDVVDI 271 Query: 344 HDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDT 391 D++ + G R+ E + RA S + D+ + D+ DT Sbjct: 272 LDMRILQEGR---RFHVESYIELRA-GLSLADADDIKFRVRDLLLTDT 315 >UniRef50_A4J2G0 Cluster: Cation diffusion facilitator family transporter; n=3; Peptococcaceae|Rep: Cation diffusion facilitator family transporter - Desulfotomaculum reducens MI-1 Length = 315 Score = 58.0 bits (134), Expect = 5e-07 Identities = 56/232 (24%), Positives = 99/232 (42%), Gaps = 17/232 (7%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 +V +I N C + KL GS + SE +HS D + LI + +S + AD D Sbjct: 10 KVARLSIISNTCLTIGKLVVGLSMGSVGVISEAVHSGLDLIASLIAFMAVRQSGKPADED 69 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGIL-DPQPLHDFYWAYFVLGGAVVSE 224 H YG+ ++ ++ + I G G+ F V IL + W V+ +S Sbjct: 70 HHYGHGKYENLAGILEALLILVAGVGI-FIQAVPKILGGGGEIESLGWGAAVM---ALSA 125 Query: 225 GATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQY 284 G +++ I G + +L + L D GV + ++ Y Sbjct: 126 GVNFIISKRLIAVGKETDSPALV---------ADGWHLKTDVYTSLGVFAGLGTIYLTGY 176 Query: 285 TGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLER 336 T L D + +I+VG ++ + +I ++G ++ S+P E+ ++I VL R Sbjct: 177 T---LLDPIIAIIVGILILKASFDLIRESLGVILDVSLPPEEEEKIKEVLRR 225 >UniRef50_Q97K27 Cluster: Cation efflux system protein; n=1; Clostridium acetobutylicum|Rep: Cation efflux system protein - Clostridium acetobutylicum Length = 292 Score = 57.6 bits (133), Expect = 6e-07 Identities = 57/276 (20%), Positives = 120/276 (43%), Gaps = 22/276 (7%) Query: 111 AIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGY 170 +I N +FKL A S S+ SE +HS D + LI + I KS D DHP+G+ Sbjct: 10 SIASNSMLIIFKLTAGITMNSISVLSEGVHSSIDLIASLIAFFSIKKSSLKEDDDHPFGH 69 Query: 171 TNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMV 230 VS + + + + + Y ++ + + +++ ++S L + Sbjct: 70 GKYENVSGFVEAI-LIMFAAIMIIYEAFNKLVSNSHVKNIDSGIYIM---LISSAVNLFI 125 Query: 231 ALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLP 290 ++ + K +++ N E + + L D GV + + + + T + Sbjct: 126 SI-ILLKSSKDTNSIALE--------ADGMHLFTDFFTSLGVFLG---LVLLKLTNIKII 173 Query: 291 DALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGID 350 D++ + LV ++ A +I ++ LV S+ + +++I ++++ I+ H ++ Sbjct: 174 DSITAFLVAILIIKTAVDLIKKSLRDLVDSSLDKDDINKIVKIVKKYPNIKEYHKLRTRR 233 Query: 351 IGSNLIRYKAEVDFDGRAL-TRSYLEKHDLNALLED 385 G+ E+D + + T S E HD+ + +ED Sbjct: 234 CGNT-----REIDIHIQIVGTDSLKETHDICSSIED 264 >UniRef50_Q8RDD5 Cluster: Predicted Co/Zn/Cd cation transporters; n=4; Thermoanaerobacter|Rep: Predicted Co/Zn/Cd cation transporters - Thermoanaerobacter tengcongensis Length = 288 Score = 57.6 bits (133), Expect = 6e-07 Identities = 62/276 (22%), Positives = 116/276 (42%), Gaps = 22/276 (7%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 + L ++ N KL A S + SE IHS D + +I + I K+ + AD D Sbjct: 5 KAALLSVVSNSFLITVKLVAGILMHSIGVISEAIHSSIDLIASIIAFFSIRKAAKPADDD 64 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 HP+G+ VS + + IF + L Y + I+ + + V+ + S Sbjct: 65 HPFGHGKYENVSGFVEAILIF-FAALLIIYEALKRIITGAYVENLGMGIVVM---LFSAL 120 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 +V+ + +E +++L M LL D GV A+ + + ++T Sbjct: 121 INSVVSFYLFKVAKKEDSIALKADAMH---------LLTDVFTSLGV---AAGLVVIRFT 168 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHD 345 G + D + +I V ++ + + + L S+P E+L EI +++ + I + H Sbjct: 169 GINILDPVIAIFVAFLIIKASVDLTKEALKDLTDTSLPEEELKEIEEIIKSNPEITSFHK 228 Query: 346 VKGIDIGSNLIRYKAEVDFDGRA-LTRSYLEKHDLN 380 ++ G K E+D R + +E H+L+ Sbjct: 229 LRTRKSGQ-----KREIDVHLRVRRDANIVEAHELS 259 >UniRef50_A7CAR0 Cluster: Cation diffusion facilitator family transporter; n=4; Ralstonia|Rep: Cation diffusion facilitator family transporter - Ralstonia pickettii 12D Length = 390 Score = 57.2 bits (132), Expect = 8e-07 Identities = 65/264 (24%), Positives = 116/264 (43%), Gaps = 27/264 (10%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R L + G+N ++ A ++ S L ++ +H+L+D + I+ S + D D Sbjct: 28 RSTLVSAGVNCVLSAGQIAAGLWSHSQGLVADGLHTLSDLIADGIVFIANRNSHKGPDED 87 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLS-FYHGVTGILDPQPLHDFYWAYFVLGGAVVSE 224 H YG+ RY ++ G+G+ VG+G + V + PQ G Sbjct: 88 HQYGHA--RYENAASLGLGLLLVGAGAGMIWAAVESLRSPQ-------------GPAPVH 132 Query: 225 GATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQY 284 G L+VAL A+ A+E L+ Y++ + +N +L A A +S +A Sbjct: 133 GPALVVALIAL--AAKE---GLFRYMLAMA-KRINSRMLIANAWHARSDAVSSLVAAVGV 186 Query: 285 TGNPLP----DALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMI 340 GN + D + + +VG ++G V + L+ R++P Q++ I + LE + Sbjct: 187 AGNLMGYHWLDPVAACVVGLMIGRVGVRFGWEALNDLMDRALPPAQVEAIRASLEATPGV 246 Query: 341 RAIHDVKGIDIGSN-LIRYKAEVD 363 +HD++ G L+ EVD Sbjct: 247 MNVHDLRTRVTGDQALVDAHIEVD 270 >UniRef50_A1AWZ0 Cluster: Cation diffusion facilitator family transporter; n=2; sulfur-oxidizing symbionts|Rep: Cation diffusion facilitator family transporter - Ruthia magnifica subsp. Calyptogena magnifica Length = 384 Score = 57.2 bits (132), Expect = 8e-07 Identities = 57/258 (22%), Positives = 120/258 (46%), Gaps = 29/258 (11%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMAD 163 S +V L ++ +FK+ A F S +L ++ IHS +D ++ ++ Y S AD Sbjct: 15 SQKVTLMGAVVDLLLAVFKIIAGFIGNSGALIADGIHSFSDLLSDGLILYATKHSALDAD 74 Query: 164 PDHPYGYTNMRYVSSLISGVGIFCVGSGLS-FYHGVTGILDPQPLHDFYWAYFVLGGAVV 222 +HPYG+ V++L G+ I GLS ++ +T + +P L Sbjct: 75 EEHPYGHKRFETVATL--GLAIILAIIGLSVIFNAMTRLANPYSL--------------- 117 Query: 223 SEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLED-----TAAVAGVIVAAS 277 ++L++++ + ++EA LY Y ++ ++ + +L + + A++ ++V Sbjct: 118 -SHSSLLLSIGTLSIFSKEA---LYWYTLKVANTYKSDLLKANAWHHRSDALSSIVVLIG 173 Query: 278 CMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERD 337 G P D++ +I+VG ++ +A + L LV SI +Q+ ++ L + Sbjct: 174 --IFGSLNGYPYLDSIAAIVVGLMVIYIAWKLGLDATKELVDTSIDAQQVTQLKHALGKI 231 Query: 338 FMIRAIHDVKGIDIGSNL 355 + ++H ++ IG + Sbjct: 232 SGVNSVHSLRTRKIGHTI 249 >UniRef50_A1SH46 Cluster: Cation diffusion facilitator family transporter; n=1; Nocardioides sp. JS614|Rep: Cation diffusion facilitator family transporter - Nocardioides sp. (strain BAA-499 / JS614) Length = 313 Score = 56.8 bits (131), Expect = 1e-06 Identities = 51/227 (22%), Positives = 98/227 (43%), Gaps = 16/227 (7%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R + ++G+ KL A+ TG +LF+E +H+L+D L ++ + ++ D + Sbjct: 25 RALKISVGVYLGILAMKLAAYLVTGVMALFAEAMHTLSDLFVSGFLLVAVYVAGRVPDRE 84 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 H +G+ V++L++ +F + Y L ++ + + +VS Sbjct: 85 HRFGHGRAENVAALVAAT-LFISFTSYQLYIEAVPALFSADEAEYSNLWLAIAVLLVSAL 143 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 A + + +R+ R A R+ L+ D +A +V +A+ Sbjct: 144 AAAVPLIGLLRRHERGA-------AARAQTQE----LINDQLGLAAALVGTVLLAV---- 188 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINS 332 G PL D + +I+V T++ A I N L+GRS E LD + + Sbjct: 189 GVPLADPIAAIVVATVIAYEAVKIFRINYSLLLGRSPDPEYLDRLQA 235 >UniRef50_A1K3F1 Cluster: Putative cobalt-zinc-cadmium resistance protein; n=1; Azoarcus sp. BH72|Rep: Putative cobalt-zinc-cadmium resistance protein - Azoarcus sp. (strain BH72) Length = 404 Score = 56.8 bits (131), Expect = 1e-06 Identities = 56/248 (22%), Positives = 108/248 (43%), Gaps = 28/248 (11%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R L AI N + ++ + + SL ++ +H+L+D V +++ + + + AD + Sbjct: 37 RAALAAICTNALLVVSQVVIGLLSNAFSLVADAMHTLSDLVTDILVLFAGRRGAEPADHN 96 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGV-TGILDPQP-LHDFYWAYFVLGGAVVS 223 HPYG+ + SL+ GV + VG+G + G+ +D P LH V+ Sbjct: 97 HPYGHGRIETFVSLLLGVALGAVGAGFLWASGMRLQHMDAAPTLHP------------VA 144 Query: 224 EGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAI-- 281 G L L A+E L+ Y + ++ + LLE A A A+S + Sbjct: 145 LGMALFTLL------AKEV---LFRYTLAAA-RRLQAPLLEANAWHARSDAASSLVVAVG 194 Query: 282 --SQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFM 339 G P + L + LVG ++ ++ V L+ ++P E++ + + + Sbjct: 195 IGGSLAGFPFLEPLAAALVGFLIAHTGWRVVAGAVRELIDTALPDEEVARLRTTIRATPG 254 Query: 340 IRAIHDVK 347 + +HD++ Sbjct: 255 VAGLHDLR 262 >UniRef50_Q97LF5 Cluster: C-terminal region cation efflux system protein CZCD; n=13; Clostridium|Rep: C-terminal region cation efflux system protein CZCD - Clostridium acetobutylicum Length = 403 Score = 56.4 bits (130), Expect = 1e-06 Identities = 65/321 (20%), Positives = 144/321 (44%), Gaps = 32/321 (9%) Query: 114 INGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNM 173 +N F+ +L + S ++ ++ H+LAD +I G S + AD +HP+G+ + Sbjct: 46 VNLILFVIELSIGIFINSIAVIADAFHNLADVSASVITLIGFKLSNKPADKEHPFGHGRV 105 Query: 174 RYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALS 233 Y+S+L+ I VG IL P+P+ ++ ++ ++ L + LS Sbjct: 106 EYLSALLVSAIILLVGVEF-IKTSFLRILSPEPV-----SFNLISFIIMLIAIPLKLWLS 159 Query: 234 AIRKG-AREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDA 292 K ++ N S + S ++N V + + ++ ++ A S ++I Y G Sbjct: 160 LFNKNIGKKINSSA---LKASGADALNDVYILSSVILSLLVSAFSTISIDGYVG------ 210 Query: 293 LGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHD--VKGID 350 +L+G ++ A ++ + L+G++ + I + + +I +HD + Sbjct: 211 ---VLIGALIIWSAVNLMKDTIDPLLGQAPDPNLVKSIKKMALKCDVILGVHDLIIHNYG 267 Query: 351 IGSNLIRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDVETFLLKHGENIV--D 408 G +I + AEV ++ +T L++ +++ +K ++++ F++ H + ++ Sbjct: 268 PGRTMISFHAEVPYNIPIMT--------LHSKIDETEK-RISEELDIFVVIHMDPLLIGS 318 Query: 409 MLGGEIDRIELKLRKKFPQIR 429 E R K+ K FP ++ Sbjct: 319 PEVSEAKRYVSKILKDFPSVQ 339 >UniRef50_A7GZD1 Cluster: MMT1 protein; n=1; Campylobacter curvus 525.92|Rep: MMT1 protein - Campylobacter curvus 525.92 Length = 372 Score = 56.4 bits (130), Expect = 1e-06 Identities = 55/242 (22%), Positives = 111/242 (45%), Gaps = 19/242 (7%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 + L I N C K+C +GS ++ ++ I++L+D + +I +G + +M D D Sbjct: 18 KTALIGIITNVCLAATKICIALVSGSVAIITDAINNLSDASSCVITIFGSKLAAKMPDED 77 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 HPYGY + Y+ L+ + + +G + I+ P+ + A +L ++ Sbjct: 78 HPYGYGRVEYIGGLVVSIVVLMLGFDF-LKTSICNII--SPVQTKFTAPLLL---ILFIA 131 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 + AL A + + S+ S +V L D A ++ VI+ ++ A+S + Sbjct: 132 IFVKFALGAHYRKVGKNTKSI-------SLKAVGTEALGD-AIISCVILFSA--ALSYFW 181 Query: 286 GNPLPDALGSIL-VGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIH 344 G + G++ + I+ GV +I ++G + E +DEI + + R ++R + Sbjct: 182 GVQIDGYAGALASLFIIINGV--LLIKETFDKIIGGRVEKEVVDEIYAAVNRCEIVRGSY 239 Query: 345 DV 346 D+ Sbjct: 240 DL 241 >UniRef50_Q0W2J0 Cluster: Predicted cation efflux protein; n=3; Euryarchaeota|Rep: Predicted cation efflux protein - Uncultured methanogenic archaeon RC-I Length = 315 Score = 56.4 bits (130), Expect = 1e-06 Identities = 59/221 (26%), Positives = 102/221 (46%), Gaps = 26/221 (11%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 + KL GS S+ SE IHS D V +I + + S + D +H +G+ + +S Sbjct: 28 ILKLIVGVMIGSVSVISEAIHSGIDLVAAVIAYFSVRTSSKPPDHEHAFGHGKLENISGT 87 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 I + IF V +G Y IL L D VS G +M+ LSAI Sbjct: 88 IEALLIF-VAAGFIIYEAYEKILHGVVLED------------VSLGIAVML-LSAI---- 129 Query: 240 REANMSLYEYVMRSSDPSVNVVLLED-----TAAVAGVIVAASCMAISQYTGNPLPDALG 294 N+ + + +M+++ + ++ L D T + + + A +AI + TG + D + Sbjct: 130 --VNLYVSQRLMKTAKRTESIALEADAWHLRTDVLTSLGIFAGLVAI-KLTGITILDPIF 186 Query: 295 SILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLE 335 +ILV + A +I+ +V L+ +P E+ +EI ++E Sbjct: 187 AILVAVFILKAAVELIVRSVKDLMDVKLPEEEENEICQIIE 227 >UniRef50_Q837I0 Cluster: Cation efflux family protein; n=1; Enterococcus faecalis|Rep: Cation efflux family protein - Enterococcus faecalis (Streptococcus faecalis) Length = 389 Score = 56.0 bits (129), Expect = 2e-06 Identities = 61/259 (23%), Positives = 115/259 (44%), Gaps = 21/259 (8%) Query: 112 IGINGCNFLF--KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYG 169 IG+ FLF K +GS S+ ++ I+SL+DT++ ++ G + + + AD +HPYG Sbjct: 31 IGLVSNLFLFVSKFMIGLLSGSVSIMADAINSLSDTISSVLTLVGFYIAGKPADKEHPYG 90 Query: 170 YTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLM 229 + Y+S ++ + I +G V IL P+ + + VL +S G + Sbjct: 91 HERFEYISGMLVSLVITFIGFEF-LTTSVDRILHPESIKVTPILFAVL---ALSIGIKIW 146 Query: 230 VALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPL 289 L + A+ + +L + S+ S N D V+++A I TG + Sbjct: 147 QGLFYKKVSAKIDSQAL----VASAKDSFN-----DVYTTLAVLISA---FIEGVTGLRI 194 Query: 290 PDALGSILVGTIL-GGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKG 348 +G ++ I+ G+ +I + L+G ++DE+ +VL + I HD+ Sbjct: 195 DGYIGFLIAAYIIYSGLQ--LIREFINELMGMRPSQTEIDEMKNVLSKMETIVGYHDLLI 252 Query: 349 IDIGSNLIRYKAEVDFDGR 367 + G + ++ D R Sbjct: 253 HNYGPSQTFASVHIEIDDR 271 >UniRef50_Q6A6E4 Cluster: Predicted Co/Zn/Cd cation transporter; n=1; Propionibacterium acnes|Rep: Predicted Co/Zn/Cd cation transporter - Propionibacterium acnes Length = 311 Score = 56.0 bits (129), Expect = 2e-06 Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 4/127 (3%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 L K AW TGS L S+ SL + V +I + S++ D +H +G++ Y S+ Sbjct: 36 LLKTLAWHITGSVGLLSDAAESLVNLVAAIIALVALKVSIRPPDMNHQFGHSKAEYFSAG 95 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 G+ IF + + + Y V L P+P+ D V A V GA + LS G Sbjct: 96 AEGMMIF-IAAAVIVYSAVERFLYPRPIADAGVGLLVSVLASVINGAVAWILLS---NGH 151 Query: 240 REANMSL 246 + +M+L Sbjct: 152 KRRSMTL 158 >UniRef50_Q6NE50 Cluster: Magnetosome protein MamB; n=5; Magnetospirillum|Rep: Magnetosome protein MamB - Magnetospirillum gryphiswaldense Length = 297 Score = 56.0 bits (129), Expect = 2e-06 Identities = 57/250 (22%), Positives = 109/250 (43%), Gaps = 19/250 (7%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 VV A + C LFK +GS +L ++ +HS AD V + + S + AD + Sbjct: 13 VVWWAFTADICMTLFKGILGLMSGSVALVADSLHSGADVVASGVTQLSLKISNKPADERY 72 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGA 226 P+GY N++Y+SS I G + +G+ Y V ++ Y A + GA Sbjct: 73 PFGYGNIQYISSAIVG-SLLLIGASFLMYGSVVKLIS-----GTYEAPSIFAAL----GA 122 Query: 227 TLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVL-LEDTAAVAGVIVAASCMAISQYT 285 ++ V ++ + M Y+ + + + S ++ D + A A I+ Sbjct: 123 SVTVIVNEL--------MYRYQICVGNENNSPAIIANAWDNRSDAISSAAVMVGVIASVI 174 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHD 345 G P+ D + +I V ++G + +I V L+ S+ E L + ++ +I+ Sbjct: 175 GFPIADTIAAIGVSALVGHIGLELIGKAVHGLMDSSVDTELLQTAWQIATDTPLVHSIYF 234 Query: 346 VKGIDIGSNL 355 ++G +G ++ Sbjct: 235 LRGRHVGEDV 244 >UniRef50_A1WC43 Cluster: Cation diffusion facilitator family transporter; n=8; Burkholderiales|Rep: Cation diffusion facilitator family transporter - Acidovorax sp. (strain JS42) Length = 319 Score = 55.6 bits (128), Expect = 2e-06 Identities = 34/137 (24%), Positives = 64/137 (46%), Gaps = 6/137 (4%) Query: 111 AIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGY 170 ++G+ + K AW+ +GS L S+ + S + + + + + AD DHPYG+ Sbjct: 24 SVGVALLTIVLKTLAWWVSGSVGLLSDALESFVNLAGAMFALAMVTIARRPADEDHPYGH 83 Query: 171 TNMRYVSSLISGVGIFCVGSGLS-FYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLM 229 Y SS GI VG+ ++ + V ++ PQPL W +G +++S + Sbjct: 84 HKAEYFSSGFE--GILIVGASIAILWAAVLRLMHPQPLEQLGWG---MGLSLLSTACNGL 138 Query: 230 VALSAIRKGAREANMSL 246 +A +R +++L Sbjct: 139 LAWGMLRAAQVHRSLAL 155 >UniRef50_A0KQ43 Cluster: Cation efflux family protein; n=2; Aeromonas|Rep: Cation efflux family protein - Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) Length = 292 Score = 55.6 bits (128), Expect = 2e-06 Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 2/127 (1%) Query: 102 TRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQM 161 TR R L ++ N + K+ A +GS S+ SE IHS D V LI + KS Sbjct: 2 TRKTRAALVSVCSNITLIIMKIFAGILSGSVSIISEAIHSAMDLVAALIALVAVRKSDIP 61 Query: 162 ADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFV-LGGA 220 D HPYG+ + VS +I + + + +G + V ++ P + V L A Sbjct: 62 PDQRHPYGHDKIENVSGVIEAL-LILLAAGWIIFEAVGKLITPTQIEGVGLGVLVMLFSA 120 Query: 221 VVSEGAT 227 +V+ G + Sbjct: 121 LVNSGVS 127 >UniRef50_Q98HP4 Cluster: Mlr2775 protein; n=12; Bacteria|Rep: Mlr2775 protein - Rhizobium loti (Mesorhizobium loti) Length = 308 Score = 55.2 bits (127), Expect = 3e-06 Identities = 24/83 (28%), Positives = 44/83 (53%) Query: 101 KTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQ 160 K + + +I + KL AW+ TGS +L+S+ + S+ + + + + I S + Sbjct: 10 KRKVANLAFWSIAVAFVVLALKLVAWYITGSVALYSDALESIVNVIASVAAFWAIQVSYK 69 Query: 161 MADPDHPYGYTNMRYVSSLISGV 183 AD DHP+G+ Y S+++ GV Sbjct: 70 PADQDHPFGHHKAEYFSAVLEGV 92 >UniRef50_A5EV87 Cluster: Cation efflux family protein; n=1; Dichelobacter nodosus VCS1703A|Rep: Cation efflux family protein - Dichelobacter nodosus (strain VCS1703A) Length = 299 Score = 55.2 bits (127), Expect = 3e-06 Identities = 62/243 (25%), Positives = 109/243 (44%), Gaps = 32/243 (13%) Query: 100 LKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 LK S V A+ + L KL AW+ +GS SL + + S D + +I + + ++ Sbjct: 8 LKRASAASVCVAVTL----MLLKLLAWWLSGSVSLLASLMDSATDILASMINLFAVRLAM 63 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSG-LSFYHGVTGILDPQPLHDFYWAYFVLG 218 AD +H YG+ +S+L +F GS + + + PQPL Sbjct: 64 CRADNNHHYGHGKAESLSAL--SQAMFITGSSFFLIINALPRLFAPQPL----------- 110 Query: 219 GAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSD-PSV---NVVLLEDTAAVAGVIV 274 T+ + + I GA A + +V++ D PSV ++ L DT GV++ Sbjct: 111 -----SHNTIGIVVMLISLGATLALVRYQHFVLKQVDSPSVHADSLHYLSDTLTGMGVLL 165 Query: 275 AASCMAISQYTGNPLPDALGSILVGT-ILGGVASFIILSNVGALVGRSIPHEQLDEINSV 333 A + ++ + D + +IL+G +L GV I+ V AL+ ++P ++D I + Sbjct: 166 A---LVLNSAFNIAIADPILAILIGIYMLYGVYQ-IVYDAVSALMDVALPEAEMDMIRAA 221 Query: 334 LER 336 + R Sbjct: 222 IAR 224 >UniRef50_A5KR43 Cluster: Putative uncharacterized protein; n=2; Ruminococcus|Rep: Putative uncharacterized protein - Ruminococcus torques ATCC 27756 Length = 396 Score = 54.4 bits (125), Expect = 6e-06 Identities = 65/278 (23%), Positives = 124/278 (44%), Gaps = 24/278 (8%) Query: 93 DNVEEVGLKTRSGRVVLTAIGINGCN-FLF--KLCAWFYTGSHSLFSECIHSLADTVNQL 149 ++VE++ ++T G V+ + +GI CN FLF K S S+ ++ ++L+D + + Sbjct: 14 EDVEKISVRTAYG-VLASIVGIF-CNVFLFAVKFTIGVIAHSVSVMADAFNNLSDAGSSI 71 Query: 150 ILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHD 209 I G+ + + AD DHP+G+ + Y+++L+ V + G +F G + + + Sbjct: 72 ISFIGVKMAEKPADRDHPFGHGRIEYIAALV--VSFLILEVGFTFLKDSIGKIRTPEMLN 129 Query: 210 FYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAV 269 F A ++ ++S G L + L R G + N + V S + D Sbjct: 130 FQIASVII--LILSIGVKLWLGLFNKRLG-EKINSKVMMAVFADS--------MGDVITT 178 Query: 270 AGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDE 329 I++ + + + TG + +G I V ++ I + L+G +I + D+ Sbjct: 179 GATILS---LIVFRITGWNIDGVVG-IGVALVVMWAGVGIAKDTLEPLIGEAIDPQVYDQ 234 Query: 330 INSVLERDFMIRAIHD--VKGIDIGSNLIRYKAEVDFD 365 I + +E+ I HD V G ++ AEV D Sbjct: 235 IKAFVEKYDGIVGTHDLIVHNYGPGRSMASIHAEVPND 272 >UniRef50_A0NZQ3 Cluster: Cation efflux transporter, CDF family protein; n=14; Bacteria|Rep: Cation efflux transporter, CDF family protein - Stappia aggregata IAM 12614 Length = 322 Score = 54.4 bits (125), Expect = 6e-06 Identities = 56/241 (23%), Positives = 108/241 (44%), Gaps = 21/241 (8%) Query: 96 EEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGI 155 E + LK R R+ +I K+ A+ TGS +L+S+ + ++ + + + + Sbjct: 24 ERMKLKRRL-RIAFLSIVFGVIVLGLKIGAYLLTGSIALYSDALETIVNIASAIATLAAV 82 Query: 156 HKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYF 215 + + AD +HPYG+ + Y ++++ VG+ V + LS + W F Sbjct: 83 WFAAKPADSNHPYGHDKVEYFAAVL--VGVMIVLAALSIFRAA-------------WLGF 127 Query: 216 VLGGAVVSEGATL-MVALSAIRKGAREANMSLYEYVMRS-SDPSVNVVLLEDTAAVAGVI 273 V G + A + M L+A+ GA + Y RS + + L+ D A+ GV+ Sbjct: 128 VNGDSPEYSPAGIGMNLLAAVINGAWARYLMQYGKHARSPALVADGKHLMTDVASSVGVL 187 Query: 274 VAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSV 333 + + TG + D ++LVG + ++ +VG L+ + H+ LD+I + Sbjct: 188 ---GGVVLVMLTGWKIMDPALAVLVGLTVLWSGWGLVKESVGGLMDEAASHDTLDKIRVL 244 Query: 334 L 334 + Sbjct: 245 I 245 >UniRef50_Q83BX5 Cluster: Cation-efflux family protein; n=2; Coxiella burnetii|Rep: Cation-efflux family protein - Coxiella burnetii Length = 378 Score = 54.0 bits (124), Expect = 7e-06 Identities = 58/255 (22%), Positives = 112/255 (43%), Gaps = 28/255 (10%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 V L + +N LFK+ + S +L ++ +HSL+D + ++ H Q D +H Sbjct: 16 VSLVSAAVNTLLALFKIVVGIFGHSQALIADGVHSLSDLLTDGLVVVTGHMGAQSPDKEH 75 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGA 226 PYG+ + + S+I V + V G++F L+ H + A+ L V Sbjct: 76 PYGHRRIETIGSIIIAVILIFVAIGIAF-----DTLE----HLIHHAHLPLPTFPV---- 122 Query: 227 TLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTA------AVAGVIVAASCMA 280 ++VA+ +I AN L+ Y + + +N LL A ++ +IV S Sbjct: 123 -IIVAVISI-----IANEGLFRYTLAKGN-QINSDLLRTNAWHNRSDSLVSLIVLIS--V 173 Query: 281 ISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMI 340 I G DA+G+ ++ ++ + +I +N L+ ++ + L +I + + Sbjct: 174 IGSRFGITYLDAIGAFIIAVLILRMGIKMIWNNGKELIDTAVDDDTLKKITETISSVPDV 233 Query: 341 RAIHDVKGIDIGSNL 355 +IH ++ G N+ Sbjct: 234 LSIHQLRTRYHGGNI 248 >UniRef50_A6F284 Cluster: Predicted Co/Zn/Cd cation transporter; n=1; Marinobacter algicola DG893|Rep: Predicted Co/Zn/Cd cation transporter - Marinobacter algicola DG893 Length = 388 Score = 54.0 bits (124), Expect = 7e-06 Identities = 53/251 (21%), Positives = 109/251 (43%), Gaps = 16/251 (6%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 RV + + ++G L K+ A S +L + IHS D V+ +++ + S Q D D Sbjct: 24 RVTVIGMLLDGVLGLLKVIAGTLFHSQALLVDGIHSFTDVVSDVVVLGVMRVSRQAPDED 83 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 HPYG+ + + +++ G + VG+ L+ + +LD ++ W VL A +S Sbjct: 84 HPYGHQRIETMGTMVLGSILIAVGAALA-WDNTLRLLDGSTVNIPEWP--VLVAAFIS-- 138 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 + + I + R +++ SD + T A++ V+V S I Sbjct: 139 ---VASKEWIYRYTRRVGLAI------RSDLIIANAWHSRTDALSSVVVLFS--TIGAML 187 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHD 345 G D L ++++ I+ + +V LV + E + + + +R +H+ Sbjct: 188 GYLWLDVLAAVIISGIIIHIGWRFTRDSVKELVDTGLSPEDTETLKHIASETDGVRNVHE 247 Query: 346 VKGIDIGSNLI 356 ++ +G +++ Sbjct: 248 LRSRRMGHDIL 258 >UniRef50_Q4IXC3 Cluster: Cation efflux protein; n=18; Pseudomonadaceae|Rep: Cation efflux protein - Azotobacter vinelandii AvOP Length = 311 Score = 53.6 bits (123), Expect = 1e-05 Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 3/90 (3%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 L K AW+ +GS SL + SL D LI +H S++ AD DH YG+ ++ L Sbjct: 45 LAKAVAWWLSGSVSLLAGLTDSLLDGAASLINLLAVHYSLRPADDDHRYGHGKAEALAGL 104 Query: 180 ISGVGIFC-VGSGLSFYHGVTGILDPQPLH 208 G +F V + L G+ +L PQPLH Sbjct: 105 --GQSVFIGVSALLVGVQGIDRLLHPQPLH 132 >UniRef50_Q3E481 Cluster: Cation efflux protein; n=5; Bacteria|Rep: Cation efflux protein - Chloroflexus aurantiacus J-10-fl Length = 324 Score = 53.6 bits (123), Expect = 1e-05 Identities = 38/141 (26%), Positives = 62/141 (43%), Gaps = 4/141 (2%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R AIG K A++ TGS + ++ + SL + +I + + + AD + Sbjct: 9 RYAWLAIGAAIATIGLKSGAFWLTGSIGILADALESLVNLAAAVIALIMLTIAARPADEE 68 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 H YG+ Y + + GV I G+ + + IL PQPL V G A + G Sbjct: 69 HAYGHGKAEYFAGALEGVFIIIAAMGIG-WTAIQRILSPQPLDHTVAGLLVAGIATLING 127 Query: 226 ATLMVALSAIRKGAREANMSL 246 VA+ +R G R +++L Sbjct: 128 G---VAIVLLRAGRRHDSLTL 145 >UniRef50_Q1LHU8 Cluster: Cation diffusion facilitator family transporter; n=3; Proteobacteria|Rep: Cation diffusion facilitator family transporter - Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) Length = 337 Score = 53.2 bits (122), Expect = 1e-05 Identities = 24/87 (27%), Positives = 45/87 (51%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R + ++ +N + + GS +L ++ +HSL+D ++ ++ + H S + AD D Sbjct: 47 RSTMVSVYVNIALSIAQAVIGIIAGSQALVADALHSLSDLISDFVVLFAGHHSRKDADTD 106 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGL 192 HPYG+ +SL G + VG G+ Sbjct: 107 HPYGHQRFETAASLAIGALLLAVGVGM 133 >UniRef50_A6PM43 Cluster: Cation diffusion facilitator family transporter; n=1; Victivallis vadensis ATCC BAA-548|Rep: Cation diffusion facilitator family transporter - Victivallis vadensis ATCC BAA-548 Length = 389 Score = 53.2 bits (122), Expect = 1e-05 Identities = 53/240 (22%), Positives = 103/240 (42%), Gaps = 21/240 (8%) Query: 109 LTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPY 168 + + N F K+ +GS ++ ++ +++L+D + ++ G + + AD +HP+ Sbjct: 32 MVGVACNVALFAAKMTVGLISGSIAVLADAVNNLSDAGSSVVALIGFRMAAKPADDEHPF 91 Query: 169 GYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATL 228 G+ + YV+ L+ V I VG F I P VVS L Sbjct: 92 GHGRLEYVAGLVIAVIIIAVGIDF-FKSAAERIFHPVE-------------TVVSNWGML 137 Query: 229 MVALS-AIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGN 287 VAL+ ++ N L + + + + L D + V+ +A A+S++T Sbjct: 138 AVALAIPVKFWMFLFNRKLGKKIDSTVLQATAFDSLSDILTTSVVLASA---AVSRFTSF 194 Query: 288 PLPDALG-SILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDV 346 P G ++ V ILGG+ ++ V L+G + ++E+ + + I +HD+ Sbjct: 195 PADGYAGVAVAVLIILGGIK--VVRDTVNPLLGECPDRQLVEELERKMLENPDICGVHDL 252 >UniRef50_Q65T10 Cluster: MMT1 protein; n=1; Mannheimia succiniciproducens MBEL55E|Rep: MMT1 protein - Mannheimia succiniciproducens (strain MBEL55E) Length = 380 Score = 52.8 bits (121), Expect = 2e-05 Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 2/120 (1%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K+ F+T S ++ + +++L+D+++ L+ G + + D HPYGY + Y+++++ Sbjct: 30 KVTIGFFTNSLAVMLDALNNLSDSLSSLVTIVGTKLATRAPDKKHPYGYGRIEYITAIVI 89 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLG-GAVVSEGATLMVALSAIRKGAR 240 G IF G+ + + I+ P+ + A ++ G VV G V S G++ Sbjct: 90 GAIIFLAGA-TALKESIAKIITPEETNYNITAIVIISIGIVVKYGLGRFVKNSGEELGSQ 148 >UniRef50_Q11X42 Cluster: Cation efflux system protein; n=8; Bacteroidetes|Rep: Cation efflux system protein - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 317 Score = 52.8 bits (121), Expect = 2e-05 Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 2/103 (1%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 + K A F+ SH+L ++ I S +D +++ +GI S + AD HPYG+ + + + Sbjct: 51 IIKWLAGFFGNSHALIADAIESTSDIFASMLILFGIKFSHKPADNKHPYGHGRIEPLITF 110 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVV 222 + VG S + Y + I P L + W VL G ++ Sbjct: 111 LV-VGFLISSSVIIAYQSIINIQTPHELPE-AWTLIVLAGIII 151 >UniRef50_A6BDG0 Cluster: Putative uncharacterized protein; n=2; Clostridiaceae|Rep: Putative uncharacterized protein - Dorea longicatena DSM 13814 Length = 296 Score = 52.8 bits (121), Expect = 2e-05 Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 3/96 (3%) Query: 109 LTAIGINGCNFL--FKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 L+ +GI G L FKL A S ++ S+ +HSL+D I G+ S + AD +H Sbjct: 17 LSTVGILGNVILTAFKLLAGIIGHSGAMISDAVHSLSDVFATFIAFLGVKLSKKSADSEH 76 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGIL 202 PYG+ + V+S++ + G G+ GV I+ Sbjct: 77 PYGHDRLECVASMVLAAILLATGIGIGM-SGVKTII 111 >UniRef50_A3VV32 Cluster: Cation efflux family protein; n=1; Parvularcula bermudensis HTCC2503|Rep: Cation efflux family protein - Parvularcula bermudensis HTCC2503 Length = 303 Score = 52.8 bits (121), Expect = 2e-05 Identities = 61/225 (27%), Positives = 98/225 (43%), Gaps = 27/225 (12%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 + K AW TGS ++ SL D + LI G+ + Q D +H +G+ +SSL Sbjct: 26 ILKAAAWIETGSVAMLGSLADSLLDLLASLIAFLGVRIAAQPPDENHRFGHAKAEAISSL 85 Query: 180 ISGVGIFCVGSGL-SFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKG 238 + V I GS + + ++DP PL A V+ V S GATL+ L A + Sbjct: 86 VQLVMI--TGSAVFVLVESIRALIDPAPLAHANLAIQVM---VASIGATLL--LVAFQTF 138 Query: 239 AREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILV 298 A + SL + S L D A AG+++A L G + Sbjct: 139 ALSRSTSL-------ATESDRAHYLGDFIANAGILLAVI-----------LTGRFGILWA 180 Query: 299 GTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAI 343 + G +A+ + +V ++ R++P + +DE S ER ++R I Sbjct: 181 DGVAGVLAAGFLFWSVISIARRALP-QLMDEEVSAAERAKILRII 224 >UniRef50_A1BEH5 Cluster: Cation diffusion facilitator family transporter; n=4; Chlorobium|Rep: Cation diffusion facilitator family transporter - Chlorobium phaeobacteroides (strain DSM 266) Length = 338 Score = 52.8 bits (121), Expect = 2e-05 Identities = 50/235 (21%), Positives = 103/235 (43%), Gaps = 19/235 (8%) Query: 101 KTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQ 160 K+ + + ++ A G+ + K AW+ T S ++ ++ + S+ + + I Y ++ S + Sbjct: 13 KSYNFQKIIAATGV--LLLIIKFGAWYLTHSVAILTDALESIVNVTSGFIGLYSLYISAK 70 Query: 161 MADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGA 220 D HPYG+ + ++S+ I G + V L V + P + + ++ Sbjct: 71 PRDSSHPYGHGKVEFISAAIEGT-LISVAGLLIINAAVDNFIHPGAVGQLDYGILLVS-- 127 Query: 221 VVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMA 280 ++ V A+R G R +++L + L DT + G+I + +A Sbjct: 128 -MTAAINWFVGSLAVRNGKRNGSLALI---------ASGRHLQSDTWSTIGIIAGLALLA 177 Query: 281 ISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLE 335 ++ T L A+ I G IL V + IL + + + E L++I ++L+ Sbjct: 178 LTGLTW--LDSAVALIFAGVIL--VTGYKILRSSLSGIMDEADTELLEKIVALLQ 228 >UniRef50_Q6LZI4 Cluster: Cation efflux protein; n=11; cellular organisms|Rep: Cation efflux protein - Methanococcus maripaludis Length = 291 Score = 52.8 bits (121), Expect = 2e-05 Identities = 60/265 (22%), Positives = 114/265 (43%), Gaps = 29/265 (10%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 + K+ A + S +L ++ +HS +D ++ +++ G+ S + AD HPYG+ + + Sbjct: 26 ILKILAGVFGKSSALIADGMHSFSDILSTVVVMLGLKLSEKPADESHPYGHERIEPALTK 85 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 I V I V + + FY G+T I+ G + T++ AL +I Sbjct: 86 ILAV-ILLVTALMIFYCGLTTIIG--------------GNYQIPGNITIIAALISI---- 126 Query: 240 REANMSLYEYVMRSSDPSVNVVLLEDT---AAVAGVIVAASCMAISQYTGNPLPDALGSI 296 +Y+Y + ++ + LL D + A V + G P+ D + SI Sbjct: 127 -FTKEWMYKYTKKGAEQIESSALLADAWHHRSDAFSSVGTLIGVVGAKLGYPILDPIASI 185 Query: 297 LVGTILGGVASFIILSNVGALVGRSIPHEQLDEINS-VLERDFMIRAIHDVKGIDIGSNL 355 ++ + +A I + L+ R+ + ++EI +L D ++ DV I SN Sbjct: 186 VISLFIAKMAFEIYFKALNQLLDRAADSKTIEEIKKIILSVDGVLEI--DVLKTRIHSNK 243 Query: 356 IRYKAEVDFDGRALTRSYLEKHDLN 380 I E+ D S +E H+++ Sbjct: 244 IYVDVEISVD---KDLSLIEAHNIS 265 >UniRef50_O30282 Cluster: Conserved hypothetical transmembrane protein; n=1; Archaeoglobus fulgidus|Rep: Conserved hypothetical transmembrane protein - Archaeoglobus fulgidus Length = 384 Score = 52.8 bits (121), Expect = 2e-05 Identities = 47/216 (21%), Positives = 98/216 (45%), Gaps = 20/216 (9%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K+ A + S +L ++ +HSL D + +++ GI + + AD HPYG+ ++ + Sbjct: 22 KVAAGIFANSTALIADGVHSLVDVLGSVLVWLGIKVAERPADASHPYGHFKAESLAEMAV 81 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQ-PLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAR 240 G+ I + S L + ++ +++ P + Y + AV +E ++A IR G + Sbjct: 82 GL-IIILSSLLIMHEAISSVINASVPTFELYAVAVAMLSAVANE----LLARYKIRVGLK 136 Query: 241 EANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGT 300 + SL + V+V L A V G Y G D++ +I + Sbjct: 137 TRSTSL---IAEGKHSRVDV--LSSLAVVVGFFFV--------YFGYWWADSVVAIAISV 183 Query: 301 ILGGVASFIILSNVGALVGRSIPHEQLDEINSVLER 336 ++ + ++ +++ L+ R + E ++ SV+E+ Sbjct: 184 VILQIGGSVLKNSIDVLMDR-VDEELALKVRSVIEK 218 >UniRef50_Q479I8 Cluster: Cation efflux protein; n=1; Dechloromonas aromatica RCB|Rep: Cation efflux protein - Dechloromonas aromatica (strain RCB) Length = 389 Score = 52.4 bits (120), Expect = 2e-05 Identities = 46/240 (19%), Positives = 105/240 (43%), Gaps = 22/240 (9%) Query: 111 AIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGY 170 ++ +N + +L + S SL + +HS +D ++ ++ Y +S AD HPYG+ Sbjct: 26 SVAVNLVMTVIQLIVGWLAHSQSLVAHGLHSFSDLLSDFLVIYASRQSAHPADEAHPYGH 85 Query: 171 TNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMV 230 M ++L+ G + +G G+ + G+ + H + E + L V Sbjct: 86 ARMETAATLVLGASLTLIGGGILWESGM------RLQH--------IEALPTVELSALWV 131 Query: 231 ALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAI---SQYTGN 287 A++ + ++EA LY Y++R ++ + +L+ + +A + + G Sbjct: 132 AIATV--VSKEA---LYRYLIRVAERLRSQLLIANALHTRADAASALVVVVGIGGALLGW 186 Query: 288 PLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVK 347 D L + L+G ++ + + + + L+ + Q++ I + L +R +H ++ Sbjct: 187 SFLDLLAAALMGFMILRMGAGLAWGAIKELIDTGLDESQVEAIRATLRETPGVRGLHQLR 246 >UniRef50_Q83PD6 Cluster: Cation-efflux pump fieF; n=70; Gammaproteobacteria|Rep: Cation-efflux pump fieF - Shigella flexneri Length = 300 Score = 52.4 bits (120), Expect = 2e-05 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R + A + L K+ AW+YTGS S+ + + SL D L + S+Q AD + Sbjct: 11 RAAIAATAMASLLLLIKIFAWWYTGSVSILAALVDSLVDIGASLTNLLVVRYSLQPADDN 70 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGL-SFYHGVTGILDPQPLHD 209 H +G+ +++L +F GS L F G+ ++ P P+ D Sbjct: 71 HSFGHGKAESLAALAQ--SMFISGSALFLFLTGIQHLVSPTPMTD 113 >UniRef50_Q9A2C4 Cluster: Cation efflux family protein; n=4; Alphaproteobacteria|Rep: Cation efflux family protein - Caulobacter crescentus (Caulobacter vibrioides) Length = 309 Score = 52.0 bits (119), Expect = 3e-05 Identities = 56/250 (22%), Positives = 104/250 (41%), Gaps = 20/250 (8%) Query: 100 LKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 ++ + RV + ++ + K AW +GS ++ + S D V LI Y + + Sbjct: 10 IRKATQRVAMLSVATAAILIVVKAIAWQASGSVAILASLSDSALDLVASLITVYAVRYAA 69 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGG 219 + D +H +G+ SSL+ G +F G+ L + L PQP+ + + G Sbjct: 70 EPPDAEHRFGHGKAEAFSSLMQGGLVFASGA-LVGREAINAWLHPQPVE-----HGLAGV 123 Query: 220 AVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCM 279 AV++ L +AL + +A+ S+ + L + A+ GV AA Sbjct: 124 AVMAISIVLTLALITAQTRVVKASGSI---AISGDRAHYAADLASNAVALVGVGAAA--- 177 Query: 280 AISQYTGNPLPDALGSILVG--TILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERD 337 + G P DA ++V I G V F S+ L+ +P +I +++ D Sbjct: 178 ----WLGLPRVDAAAGLIVALWLIWGAVGVFREASH--QLMDHELPDADRTKIVALVTAD 231 Query: 338 FMIRAIHDVK 347 + +H ++ Sbjct: 232 PNVLGVHQLR 241 >UniRef50_Q18YB5 Cluster: Cation diffusion facilitator family transporter; n=4; Clostridiales|Rep: Cation diffusion facilitator family transporter - Desulfitobacterium hafniense (strain DCB-2) Length = 388 Score = 52.0 bits (119), Expect = 3e-05 Identities = 61/263 (23%), Positives = 112/263 (42%), Gaps = 22/263 (8%) Query: 93 DNVEEVGLKTRSGRVVLTAIGINGCN---FLFKLCAWFYTGSHSLFSECIHSLADTVNQL 149 +N+ + ++ + G V+ A+GI CN F+ KL + S ++ S+ ++L+D + + Sbjct: 14 ENISDKRVREQYG-VLAGALGII-CNLILFILKLLLGLFMNSIAVISDAFNNLSDCGSSV 71 Query: 150 ILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHD 209 I S + D +HP+G+ + Y+SSL+ IF VG L + T IL P+ + Sbjct: 72 IAIIAAKMSNRPPDIEHPFGHGRIEYISSLVVSFIIFMVGIEL-LKNSFTKILHPEEVL- 129 Query: 210 FYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAV 269 F W V+ ++ + S R N + + ++ S+N L + Sbjct: 130 FSWISLVI---LLFSVVLKIWMFSYNRYIGHTINSGINK---ATAYDSLNDALATSAVIL 183 Query: 270 AGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDE 329 + +I A +AI Y G +L+ + + V L+G S E ++ Sbjct: 184 STLIGHAFDLAIDGYVG---------LLISLFILYTGYNVAKETVNILLGSSPNPELCNQ 234 Query: 330 INSVLERDFMIRAIHDVKGIDIG 352 + + I HD+K D G Sbjct: 235 VKDFVNEGMYIIGTHDLKVHDYG 257 >UniRef50_Q0BW07 Cluster: Cobalt-zinc-cadmium resistance protein czcD; n=1; Granulibacter bethesdensis CGDNIH1|Rep: Cobalt-zinc-cadmium resistance protein czcD - Granulobacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) Length = 306 Score = 52.0 bits (119), Expect = 3e-05 Identities = 61/240 (25%), Positives = 105/240 (43%), Gaps = 24/240 (10%) Query: 101 KTRSGRVVLTAIG--INGCNFL-FKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHK 157 +T S R + A G + G L KL AW T S +LFS+ + S+ + L+ + Sbjct: 8 ETSSRRTKMVASGTIVIGIVVLGLKLLAWRMTNSTALFSDAMESIVNVAASLMAFAALVY 67 Query: 158 SVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVL 217 + + AD +HPYG+ + + +++ G + V + F I P+ L D ++ L Sbjct: 68 AQRPADDNHPYGHGKIEFFAAVGEG-ALILVAAMAIFQEAWHAIQQPRILLDAPFSGIAL 126 Query: 218 GGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNV---VLLEDTAAVAGVIV 274 GA AT++ L R L + R+ PS+ LL D + +GV+ Sbjct: 127 NGA-----ATMLNGLWGWR---------LMKTARRTHSPSLKADASHLLNDVVSSSGVVA 172 Query: 275 AASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVL 334 + + G P+ D L + LV + +I +VG L+ + + L+ I SV+ Sbjct: 173 G---LLGAWLVGQPILDPLLAGLVAVYILWSGFRLIRESVGGLMDEAPTPDVLERIRSVV 229 >UniRef50_A3CXT0 Cluster: Cation diffusion facilitator family transporter; n=2; Methanomicrobia|Rep: Cation diffusion facilitator family transporter - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 416 Score = 52.0 bits (119), Expect = 3e-05 Identities = 66/288 (22%), Positives = 124/288 (43%), Gaps = 26/288 (9%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 RV ++ +N + KL YTGS +L ++ IHS D V L L G++ S + D Sbjct: 21 RVAFLSLAVNAGLVVAKLLLSVYTGSLALRADGIHSFVDVVASLALIVGVYLSSRKR-RD 79 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 PYG + V ++ + IF ++ VTG QP Y + +L A Sbjct: 80 FPYGLYKVENVVAVAIALLIFFTAFEIA-AEAVTGDAAAQP----YSGWVLLAVAAFIPV 134 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 ++ G E N+ + + PS+ + V V + + Q+ Sbjct: 135 PYIL--------GTYEVNVG-----RKYNSPSLIADGRQHRVDVLSSSVVFFAL-LGQFF 180 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHD 345 G PL D + +++V + I+ ++ L+ S+ ++ L+EI S++ D + I Sbjct: 181 GIPL-DRIAAVVVAVFIVRAGWGILKDSMRTLLDASVDYDTLNEIRSIILSDPKVSGIKS 239 Query: 346 VKGIDIGSNL----IRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKI 389 + G + G + + AE DF G+A S + D+ +++++++ Sbjct: 240 ITGRNSGRYIFVEAMVEMAESDF-GKAHRESERIEQDIRLRVQNVERV 286 >UniRef50_Q0KAF7 Cluster: Cobalt-zinc-cadmium resistance protein czcD; n=1; Ralstonia eutropha H16|Rep: Cobalt-zinc-cadmium resistance protein czcD - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier337)) Length = 194 Score = 51.6 bits (118), Expect = 4e-05 Identities = 30/76 (39%), Positives = 39/76 (51%) Query: 108 VLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHP 167 V AI N K TGS ++ SE IHS DT N+L+L G+ +S + AD HP Sbjct: 36 VYGAIAANVAIAATKFVVAAVTGSSAMLSEAIHSTVDTGNELLLLVGMARSRRPADAMHP 95 Query: 168 YGYTNMRYVSSLISGV 183 +GY Y SL+ V Sbjct: 96 FGYGKELYFWSLMVAV 111 >UniRef50_Q1EYD3 Cluster: Cation efflux protein precursor; n=1; Clostridium oremlandii OhILAs|Rep: Cation efflux protein precursor - Clostridium oremlandii OhILAs Length = 297 Score = 51.2 bits (117), Expect = 5e-05 Identities = 51/251 (20%), Positives = 111/251 (44%), Gaps = 17/251 (6%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R+VL I +N L K+ A + S +L ++ +HS +D + + + G+ + + D Sbjct: 13 RIVLITIALNIFLLLIKVIAGIASNSTALIADGLHSGSDVITSVGVIIGMAMASKPRDEH 72 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 H YG+ + +++ + + + VG+ + Y ++ IL + + ++YF L A+VS Sbjct: 73 HHYGHEKIETITTFLLSIVLIYVGAQIG-YSALSAILRKEQV---LFSYFGLFAALVSII 128 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 + A R G RE + +L + L A+ G++ A Sbjct: 129 IKEIQYQIAYRVGTREKSAALIADAWHHRSDA-----LSSIASFIGILGAK--------F 175 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHD 345 G + D++ +V I+ V I L+ SI +++ + ++ ++ ++ I D Sbjct: 176 GISILDSMAGFIVSLIVIKVGVHIFKECFQELIDVSIHLDEVSNLKKIILKETSVKYISD 235 Query: 346 VKGIDIGSNLI 356 ++ G+ ++ Sbjct: 236 LRTRKHGAKVL 246 >UniRef50_A6ECE5 Cluster: Cation efflux protein; n=1; Pedobacter sp. BAL39|Rep: Cation efflux protein - Pedobacter sp. BAL39 Length = 307 Score = 51.2 bits (117), Expect = 5e-05 Identities = 67/279 (24%), Positives = 120/279 (43%), Gaps = 31/279 (11%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 L K A+F T S+++ ++ S+ + + Y I+ + D +HPYG+ + + S+ Sbjct: 2 LAKFVAYFMTHSNAILTDAAESIVNVLASGFAFYSIYLATLPKDENHPYGHGKVEFFSAF 61 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 + GV I G + F G +L P + Y ++G V+ L L I G Sbjct: 62 VEGVLIALAGLIIIFKSGY-DLLFPVAIRQLYEGAIIIG---VTGLINLFTGLYLINTGK 117 Query: 240 REANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVG 299 R ++++L +D LL D G+++ + + Q T D++ SIL+G Sbjct: 118 RHSSITL------EAD---GKHLLTDAVTSGGLVIG---VLLIQLTEIFWLDSVISILLG 165 Query: 300 TILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDF--MIRAIHDVKGIDIGS-NLI 356 I+ N L RS+ +DE N L +D +++A ID+ + Sbjct: 166 --------MYIIRNGYQLTRRSV-GGLMDESNMELVKDIVGIMQAHRHDAWIDVHNLRAQ 216 Query: 357 RYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDV 395 +Y A++ D Y DLN + ++ ID + +V Sbjct: 217 QYGADLHIDCHVTLPYYF---DLNRVHAEISSIDQLINV 252 >UniRef50_Q8PTD7 Cluster: Cobalt-zinc-cadmium resistance protein; n=2; Methanosarcina|Rep: Cobalt-zinc-cadmium resistance protein - Methanosarcina mazei (Methanosarcina frisia) Length = 357 Score = 50.8 bits (116), Expect = 7e-05 Identities = 61/284 (21%), Positives = 126/284 (44%), Gaps = 26/284 (9%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 RV + +N +FKL A S ++ ++ +HSL+D + +++ +G + + D Sbjct: 41 RVTGVGLFVNLGLTIFKLLAGILGNSTAMVADAVHSLSDFLTDVVVIFGFKIAKKPVDES 100 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 H YG+ + +S+ + G+ + V +G Y+GV L F+ G + Sbjct: 101 HNYGHGKIETLSASLVGLMLLLV-AGQILYYGVQKTL-----------MFIEAGTLEQPA 148 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAI---- 281 ++AL A + +Y+Y + + ++ L + ++ C I Sbjct: 149 ---IIALYAALASVISKEI-MYQYTILKARKINSMALTANAWHHRSDAFSSFCTMIGIGA 204 Query: 282 SQYTGNP--LPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFM 339 + + G + D L ++ + I+ V+ I S++ LV S+ + EI ++++ Sbjct: 205 AVFLGGKWVVLDPLMAVFLSFIILKVSLKIFHSSINELVEASLDEKTESEIRQIIQKTEG 264 Query: 340 IRAIHDVKGIDIGSNL---IRYKAEVDFD-GRALTRSYLEKHDL 379 ++A+ ++K IG+N+ IR K + D G A S +H+L Sbjct: 265 VKALSNLKTRRIGNNIAVDIRIKVDNALDIGEANRISIHVEHNL 308 >UniRef50_UPI0000383D2E Cluster: COG0053: Predicted Co/Zn/Cd cation transporters; n=1; Magnetospirillum magnetotacticum MS-1|Rep: COG0053: Predicted Co/Zn/Cd cation transporters - Magnetospirillum magnetotacticum MS-1 Length = 460 Score = 50.4 bits (115), Expect = 9e-05 Identities = 32/118 (27%), Positives = 56/118 (47%), Gaps = 3/118 (2%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 V ++++ + + KL TGS + SE HSL D L+ + + Q AD H Sbjct: 9 VAISSVLASAAMTVMKLVVGLMTGSLGILSEAAHSLLDMGAALLTWFAVRIGDQPADERH 68 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILD--PQPLHDFYWAYFVLGGAVV 222 PYG+ + VS+LI G+ V + V+ +L+ P + +WA V+ +++ Sbjct: 69 PYGHGKVESVSALIE-TGLLFVTAAWIIKEAVSRLLESTPPEVETTWWAVAVIVVSII 125 >UniRef50_Q5P2F7 Cluster: Putative uncharacterized protein; n=1; Azoarcus sp. EbN1|Rep: Putative uncharacterized protein - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 317 Score = 50.4 bits (115), Expect = 9e-05 Identities = 57/216 (26%), Positives = 96/216 (44%), Gaps = 22/216 (10%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K AW+ TGS S+ + SL + + + ADP+HPYG+ Y S+ Sbjct: 55 KAGAWWLTGSVGFLSDALESLVNLAGASFALLMVSLARAPADPEHPYGHGKAEYFSAAFE 114 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLG-GAVVSEGATLM-VALSAIRKGA 239 G+ IF V + + V ++ PQPL LG G V+S GA+L+ + ++ I Sbjct: 115 GMLIF-VAALVILATAVERLIHPQPLG-------ALGLGTVLSVGASLVNLVVARILFQV 166 Query: 240 REANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTG-NPLPDALGSILV 298 A+ SL +D L+ D AGV+ ++S + +PL A + V Sbjct: 167 GRAHRSL----ALEADAR---HLMTDVWTTAGVVAGVGLASLSGWNWLDPLVAA--GVAV 217 Query: 299 GTILGGVASFIILSNVGALVGRSIPHEQLDEINSVL 334 + G ++ +V L+ R++ ++ I +VL Sbjct: 218 NILREGWG--LMHRSVDGLMDRALDDAEIRHIEAVL 251 >UniRef50_P96691 Cluster: YdfM protein; n=2; Bacillus|Rep: YdfM protein - Bacillus subtilis Length = 297 Score = 50.4 bits (115), Expect = 9e-05 Identities = 62/265 (23%), Positives = 122/265 (46%), Gaps = 16/265 (6%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMAD 163 S +V L A+ N K+ S ++F++ IHS AD V + + I S + D Sbjct: 9 SRKVALIALIANLILMAGKVFFGLVGDSEAVFADGIHSAADVVASIAVLAVIGISNKPPD 68 Query: 164 PDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILD--PQPLHDFYWAYFVLGGAV 221 DHP+G+ +S I G+ + V S Y + IL P Y A F A+ Sbjct: 69 QDHPFGHGKAEVISEAIVGIILVIV----SVYILIEAILSFVKGPSVPQYSALF---AAL 121 Query: 222 VSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAI 281 +S A ++ +I++G + + ++ + + D ++V AA GV++A + Sbjct: 122 ISYVAKEILYRYSIKQGKKWNSKAI---IAIAYDHKGDIV--ASLAAFIGVLLAIIGNS- 175 Query: 282 SQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIR 341 ++ DA+ S +V ++ ++ +I +VG L+ +S+ E ++E +V+ + ++ Sbjct: 176 RGWSYLLYADAIASAIVAYLIFKISMELIRPSVGVLMEKSVDPELIEEYKAVIFQCDQVK 235 Query: 342 AIHDVKGIDIGS-NLIRYKAEVDFD 365 I ++ + G L+ + +D D Sbjct: 236 RIDRIRAREHGHYKLLDVRLSLDHD 260 >UniRef50_Q0AY41 Cluster: Putative cation efflux system protein; n=1; Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep: Putative cation efflux system protein - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 319 Score = 50.4 bits (115), Expect = 9e-05 Identities = 50/246 (20%), Positives = 109/246 (44%), Gaps = 21/246 (8%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 + K S SL ++ +H+ +D + L++ G + AD +HP+G+ + ++++L Sbjct: 52 IIKFIMGILVNSISLIADAVHTASDVLTSLVVIIGFKLAALPADEEHPHGHGRIEFIATL 111 Query: 180 ISGVGIFCVGSGLSF-YHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKG 238 + + + + G+ F + ++ P+ +YFV+ +M+ ++ Sbjct: 112 V--ISLLLIAVGIKFGFDSYKRLIANTPVAG---SYFVV---------VVMLFAGLFKEW 157 Query: 239 AREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILV 298 ++ L + + SS + T A+A V+VA + +A S++ G DA+ +V Sbjct: 158 MSRFSIDLGQRI--SSSTLIADAWHHRTDAIASVLVAIAILA-SKF-GYYWVDAVLGFVV 213 Query: 299 GTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSN-LIR 357 ++ I + ++G EQ+ +N + + A+HD D G+N ++ Sbjct: 214 SALIVWTGIEIFRESCSKIIG-EYDEEQVKRVNQLALAIPGVIAVHDTSVHDYGANKVVS 272 Query: 358 YKAEVD 363 EVD Sbjct: 273 LHIEVD 278 >UniRef50_A5Z978 Cluster: Putative uncharacterized protein; n=2; Bacteria|Rep: Putative uncharacterized protein - Eubacterium ventriosum ATCC 27560 Length = 588 Score = 50.4 bits (115), Expect = 9e-05 Identities = 30/118 (25%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Query: 86 MSHTRSKDNVEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADT 145 M+ K+ + + K + +V +I +N +FKL A S ++ S+ IHS +D Sbjct: 23 MTRIEKKEILSDEKTKKVAMQVSTVSIVVNLLLSVFKLLAGIIGKSGAMVSDAIHSASDV 82 Query: 146 VNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILD 203 + I+ G+ + + +D H YG+ + V+++I V + G+G+ GV I++ Sbjct: 83 FSSFIVIIGVSLAGKESDEGHQYGHDRLECVAAIILAVVLLITGAGIGI-DGVNKIIN 139 >UniRef50_Q7NKM3 Cluster: Gll1454 protein; n=3; Bacteria|Rep: Gll1454 protein - Gloeobacter violaceus Length = 319 Score = 50.0 bits (114), Expect = 1e-04 Identities = 51/213 (23%), Positives = 85/213 (39%), Gaps = 16/213 (7%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K A+ TGS L S+ S + V L+ + + + + D HP+G++ Y SS + Sbjct: 31 KFGAYVLTGSVGLLSDAAESGINLVTALVTFWALTVAARAPDQTHPFGHSKAEYFSSGLE 90 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGARE 241 G I G++ V + DPQPL + A G V +A G R Sbjct: 91 GALILLAAVGIA-VTAVGRLFDPQPLEQLGLGMVLSLVATALNGGVAAVLTAA---GKRL 146 Query: 242 ANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTI 301 +++L LL D AGV+V + + Q TG + D L ++ V Sbjct: 147 RSLALQADAQH---------LLTDVWTSAGVVVG---LVLVQLTGWLILDPLIALAVAVN 194 Query: 302 LGGVASFIILSNVGALVGRSIPHEQLDEINSVL 334 + A ++ + L+ ++ E I +L Sbjct: 195 IVWAALRLLRESADGLMDSALSDEDTRSIERIL 227 >UniRef50_A3XEG4 Cluster: Cation efflux system protein; n=9; Proteobacteria|Rep: Cation efflux system protein - Roseobacter sp. MED193 Length = 305 Score = 50.0 bits (114), Expect = 1e-04 Identities = 38/136 (27%), Positives = 70/136 (51%), Gaps = 7/136 (5%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQM-ADP 164 R V AI NG + ++ +GS +L ++ +H+ +D + L++A+ K + AD Sbjct: 17 RRVAIAIWANGLLTVAQIVGGILSGSLALIADALHNFSDMAS-LVIAFAARKIARRPADE 75 Query: 165 DHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGG-AVVS 223 +GY + V++LI+ + +G L Y G ++DP + W +LGG A+V Sbjct: 76 RMTFGYGRVEIVAALINYTTLIVIGFYL-IYEGGMRMIDPPEV--MGWTVVILGGIALVV 132 Query: 224 EGATLMVALSAIRKGA 239 + T M+ S ++KG+ Sbjct: 133 DTLTAMLTYS-MQKGS 147 >UniRef50_A5ULB6 Cluster: Cation efflux system protein; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Cation efflux system protein - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 301 Score = 50.0 bits (114), Expect = 1e-04 Identities = 61/298 (20%), Positives = 124/298 (41%), Gaps = 23/298 (7%) Query: 101 KTRSG-RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 +T+ G + + IG N +F + +GS++L SE H+L+D +I G Sbjct: 5 RTKGGTKAAIVGIGSNTFLTIFNIGIGIISGSYALISEGAHTLSDVATSIIAYLGFRIGQ 64 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHG-VTGILDPQPLHDFYWAYFVLG 218 + AD +HP G+ ++ LI + +F G + I+ P+ + +Y Sbjct: 65 KPADEEHPLGHGRAEAIAGLI--IVLFLTMVAYEIMTGAINKIVHPELITT--PSYLAAV 120 Query: 219 GAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASC 278 A++ G L ++ I G + + ++ V + V++ A + GV + S Sbjct: 121 MALIGIGVNLCISRYIIALGKKIRSPAI---VADGNHQKVDI--FSSVAILVGVFASNS- 174 Query: 279 MAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDF 338 G + D + +++G + A I N+ ++G+ E + +I + Sbjct: 175 -------GYSIIDPVIGLIIGLFVLKTAYTIGKENIDNIMGKIPSKELIKDIEKAATKTP 227 Query: 339 MIRAIHDVKGIDIGS-NLIRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDV 395 + H++K +GS +++ E+D + L S+ H A +KK+ + V Sbjct: 228 QVLGAHNIKVEYLGSYSVVSLHIELD-ENMTLKESHKIVH--RAQNNVLKKVPLVKSV 282 >UniRef50_Q3AES4 Cluster: Cation efflux family protein; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: Cation efflux family protein - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 303 Score = 49.6 bits (113), Expect = 2e-04 Identities = 55/242 (22%), Positives = 104/242 (42%), Gaps = 16/242 (6%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 LFK+ +TGS S+ +E +HS D + +I + + + + AD HPYG+ + ++ Sbjct: 21 LFKIVVGLFTGSVSIIAEGLHSGVDLLASIITFFSVKVASRPADVRHPYGHGKVENIAGT 80 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLG-GAVVS--EGATLMVALSAIR 236 I G+ IF +G+ L + P+ W V+ A+V+ TL+ Sbjct: 81 IEGLLIF-LGAVLIIKEALPKFWHPEMPESLGWGMGVMAVSALVNFFISQTLLKIAKETD 139 Query: 237 KGAREAN-MSLYEYVMRSSDPSVNVVLLEDTA----------AVAGVIVAASCMAISQYT 285 A EA+ L V S+ + ++L++ T VAG+I+ A+ + Sbjct: 140 SPALEADGWHLRTDVYTSAGVLLGLLLIKLTGITYFDPILALIVAGMILKAAYEITFEGF 199 Query: 286 GNPLPDALGSILVGTILGGVASF-IILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIH 344 N + AL + I +A++ L R E+ +++ V+ ++ +H Sbjct: 200 ANMVDTALPEKEIALIKDSIANYGEKFLEFHKLRARKSGSERFIDLHLVVPEKLSVKEVH 259 Query: 345 DV 346 D+ Sbjct: 260 DL 261 >UniRef50_Q9KDH5 Cluster: Cation efflux system; n=4; Bacillaceae|Rep: Cation efflux system - Bacillus halodurans Length = 300 Score = 49.2 bits (112), Expect = 2e-04 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Query: 131 SHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGS 190 S +L ++ +HS +D V+ +++ G+ + D DHPYG+ V+S+I V +F VG Sbjct: 38 SKALIADAVHSASDVVSSVVVLIGVRAAKMPPDEDHPYGHGKAESVASIIVAVLLFIVGF 97 Query: 191 GLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 ++ +P + Y VL V EG Sbjct: 98 EIA-VSAFQSFFEPVEVPRTLAIYAVLISIFVKEG 131 >UniRef50_Q2JWZ6 Cluster: Cation transporter, cation diffusion facilitator (CDF) family; n=7; Cyanobacteria|Rep: Cation transporter, cation diffusion facilitator (CDF) family - Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime) Length = 304 Score = 49.2 bits (112), Expect = 2e-04 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 3/102 (2%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 RV+ +G+N F KL TGS SL ++ +HS+ D+ + ++ S D D Sbjct: 19 RVLYVTLGLNLLVFSVKLILGLATGSLSLVADALHSVTDSASNILALLAARFSSPEPDED 78 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTG-ILDPQP 206 HPYG + + +L G+ F + G PQP Sbjct: 79 HPYGRSKFEAIGAL--GIAAFLGVASFEILSAAVGRFFAPQP 118 >UniRef50_Q565Y9 Cluster: Predicted Co/Zn/Cd cation transporter; n=1; uncultured bacterium|Rep: Predicted Co/Zn/Cd cation transporter - uncultured bacterium Length = 369 Score = 49.2 bits (112), Expect = 2e-04 Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 5/137 (3%) Query: 108 VLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHP 167 +L ++ ++ + KL A++ T S ++ S+ S+ V + A+ + + + AD DHP Sbjct: 65 ILVSLLVSVVMLVGKLSAYYLTRSTAILSDAAESIVHCVATALAAFSLWYAGRPADADHP 124 Query: 168 YGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGAT 227 YG+ + Y S+ G +F + + + G+L L + GG + Sbjct: 125 YGHGRIAYFSAGFEGALVFAASIAVG-WSAIAGLLRAPQLQHLGLGMAIAGGLAL---IN 180 Query: 228 LMVALSAIRKGAREANM 244 L++ L+ +R G R+ N+ Sbjct: 181 LVLGLALLRIG-RQHNV 196 >UniRef50_A3X492 Cluster: Cation efflux transporter, CDF family protein; n=4; Rhodobacteraceae|Rep: Cation efflux transporter, CDF family protein - Roseobacter sp. MED193 Length = 298 Score = 49.2 bits (112), Expect = 2e-04 Identities = 21/64 (32%), Positives = 37/64 (57%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 KL AW+ TGS +L S+ + SL + ++ +H + + AD HP+G+ Y S+++ Sbjct: 24 KLVAWWLTGSVALLSDALESLVNVGGAVMAWMAVHYAKRPADAGHPFGHYKAEYFSAVLE 83 Query: 182 GVGI 185 G+ I Sbjct: 84 GIMI 87 >UniRef50_A7DRF6 Cluster: Cation diffusion facilitator family transporter; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Cation diffusion facilitator family transporter - Candidatus Nitrosopumilus maritimus SCM1 Length = 450 Score = 49.2 bits (112), Expect = 2e-04 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Query: 119 FLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSS 178 FL +L + S +L ++ IH+L D+V L+L +++ D +H YG+ + + Sbjct: 20 FLVELVFGLVSNSLALITDSIHALLDSVVTLVLLLAARMAIKPPDAEHTYGHGKIESLGG 79 Query: 179 LISGVGIFCVGSGLSFYHGVTGILDPQP 206 LI G+ IF + Y + I P P Sbjct: 80 LIGGIAIFLIAC-FFIYESIHRIQSPPP 106 >UniRef50_Q2W8Q4 Cluster: Predicted Co/Zn/Cd cation transporters; n=3; Magnetospirillum|Rep: Predicted Co/Zn/Cd cation transporters - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 318 Score = 48.8 bits (111), Expect = 3e-04 Identities = 31/117 (26%), Positives = 58/117 (49%), Gaps = 3/117 (2%) Query: 112 IGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYT 171 + +N + K GS ++ ++ ++SL D +N L++ G S + D +HPYG+ Sbjct: 18 LAVNTVLMVMKAFVGLIGGSQAMLADAMYSLKDMLNALMVVIGTTISSKPLDAEHPYGHG 77 Query: 172 NMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATL 228 + ++ S++ V +F +G H V +LD + +H VL A+VS G + Sbjct: 78 KVEFILSMVVSV-VFIGLTGYLLVHAVQILLD-ESMHRTP-HLIVLWAALVSVGVNV 131 >UniRef50_Q2W8P3 Cluster: Predicted Co/Zn/Cd cation transporters; n=2; Magnetospirillum|Rep: Predicted Co/Zn/Cd cation transporters - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 333 Score = 48.8 bits (111), Expect = 3e-04 Identities = 51/233 (21%), Positives = 102/233 (43%), Gaps = 17/233 (7%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 +FK +GS +L + +HS D + + I + S + A+ PYGY ++++S+ Sbjct: 31 VFKTALGVLSGSMALQAHSLHSFGDFLTKGINLASVKLSSRPANSAFPYGYGKVQFLSAN 90 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 G+ + G+ ++ VT + WA F GA++S G T + +R A Sbjct: 91 FIGISLM-AGAAAMLWYNVTHLGSGHVQVPEVWAVF---GALISAG-TAELMHRYLRCVA 145 Query: 240 REANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVG 299 N + ++D + A +AG++++ G D L +ILV Sbjct: 146 EHTNSP--AIMAAAADNRGDA--YSSLAVLAGIVLS--------ILGWVAADHLAAILVS 193 Query: 300 TILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIG 352 ++ + + I ++ L+ S+P ++D I +L ++ D++G +G Sbjct: 194 LLVLRIGAVIAWDSIHGLMDGSVPSHRIDGIRQLLAAHHPGVSVVDLRGRRMG 246 >UniRef50_O85143 Cluster: Transport protein; n=35; Bacteria|Rep: Transport protein - Staphylococcus aureus Length = 326 Score = 48.8 bits (111), Expect = 3e-04 Identities = 55/260 (21%), Positives = 107/260 (41%), Gaps = 17/260 (6%) Query: 86 MSHTRSKDNVEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADT 145 MSH+ + + T + V+ + I G ++ S +L + IH +DT Sbjct: 1 MSHSHHHHDHMHSHVTTNNKEVLFISFLIIGLYMFIEIIGGLLANSLALLRDGIHMSSDT 60 Query: 146 VNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQ 205 + + + + A +GY +++L +GV +F + S L + +T P Sbjct: 61 FSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVI-SILIVFEAITRFFVPS 119 Query: 206 PLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLED 265 + + G +V+ ++VA + G N++ MR + V + D Sbjct: 120 EVQSKEMLIISIIGLIVN----IVVAFFRFKGGDTSHNLN-----MRGAFLHV----IGD 166 Query: 266 TAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHE 325 G I AA + +T + D + SILV I+ A I S++ L+ + Sbjct: 167 LLGSVGAITAAILIWAFGWT---IADPIASILVSVIILKSAWGITKSSINILMEGTPSDV 223 Query: 326 QLDEINSVLERDFMIRAIHD 345 +DE+ + + +D I+++HD Sbjct: 224 DIDEVITTITKDSRIQSVHD 243 >UniRef50_A5FYR2 Cluster: Cation diffusion facilitator family transporter precursor; n=1; Acidiphilium cryptum JF-5|Rep: Cation diffusion facilitator family transporter precursor - Acidiphilium cryptum (strain JF-5) Length = 295 Score = 48.8 bits (111), Expect = 3e-04 Identities = 49/214 (22%), Positives = 93/214 (43%), Gaps = 18/214 (8%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K AW + S +L+S+ + SL + +++ + + + AD +HPYG+ +S++ Sbjct: 22 KAAAWRVSHSAALYSDALESLVNVFAAVMVMIALKAAAKPADSEHPYGHAKAELLSAVAE 81 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQ-PLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAR 240 G G+ + L + IL P+ P+ G VV+ + AL+ R GA Sbjct: 82 G-GMIIFAAVLILERAASTILAPRLPVAPELGLGLNAAGGVVN----ALWALALGRSGAT 136 Query: 241 EANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGT 300 ++ ++D L+ D G+I S ++ P+ D L +I V Sbjct: 137 R------KFPALAAD---QAHLIADAITTLGIIGGLSLAILANL---PVLDPLIAIAVAA 184 Query: 301 ILGGVASFIILSNVGALVGRSIPHEQLDEINSVL 334 + + +L + AL+ R+ P E +D I ++ Sbjct: 185 QIAFMGGRTVLRALSALLDRAPPPEMVDRIRHLV 218 >UniRef50_Q5ZTX4 Cluster: Cation efflux family protein; n=4; Legionella pneumophila|Rep: Cation efflux family protein - Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM 7513) Length = 387 Score = 48.4 bits (110), Expect = 4e-04 Identities = 57/291 (19%), Positives = 125/291 (42%), Gaps = 21/291 (7%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 +V L IN + K+ F SH+L ++ +HS++D + + + + AD Sbjct: 19 KVTLIGAFINALLGVVKMIGGFLYHSHALIADGVHSISDLITDVTVVFASKYGSVSADDS 78 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 HPYG+ + ++L+ + + G G++ + + +L + + ++ ++++ Sbjct: 79 HPYGHQRIETAATLLLSLLLILAGCGIA-WDALDELLKSDHTMPNWLSIPIVCFSIIANE 137 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 A L + K ++ + RS S VVL+ ++AG++ Sbjct: 138 A-LFHYTRHVGKKISSQLITANAWHHRSDAASSIVVLIGLIGSLAGLVYL---------- 186 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHD 345 DA+ +++V ++ + ++V LV ++ E +I V++ ++ IH Sbjct: 187 -----DAIAAVIVSLMIIKMGWSYGWNSVKELVDTAVDAELFSQIERVIQSIDGVKRIHQ 241 Query: 346 VKGIDIGSN-LIRYKAEVDFDGRALTRSYLEKHDLNALLEDMKKIDTIDDV 395 ++ +GS+ LI V Y+ +H + L +K+ID + DV Sbjct: 242 LRSRFMGSDVLIDVHILVSPKISVSEGHYIAQHVHHTL---VKEIDCVKDV 289 >UniRef50_A7GZ19 Cluster: Pantothenate metabolism flavoprotein; n=2; Campylobacter|Rep: Pantothenate metabolism flavoprotein - Campylobacter curvus 525.92 Length = 311 Score = 48.4 bits (110), Expect = 4e-04 Identities = 47/225 (20%), Positives = 103/225 (45%), Gaps = 16/225 (7%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 + K A +GS ++ S I S+ D + L+ + + KS A+ + +GYT + +++L Sbjct: 37 VIKFIAGIASGSVAVMSSAIDSILDFIVSLLNFFALKKSRAAANENFNFGYTKLEAMAAL 96 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 GV I + + + FY + D + +V+ ++V GA L+ LS++ K Sbjct: 97 FEGVFIIGIAAFI-FYESILKFKQDDAAIDVGASLWVMCFSLVVTGA-LIAFLSSVAK-- 152 Query: 240 REANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVG 299 R N+ ++R+ + A +A +IV ++TG + DA+ +++ Sbjct: 153 RTDNL-----ILRADALHYKSDFYTNLAVIAALIVI-------KFTGLMIVDAVLGLIIS 200 Query: 300 TILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIH 344 + A ++ + L+ R++ ++ I ++++ I + H Sbjct: 201 GYIAHSAVNLMKESFAVLLDRALEPAMIEAIKNMIKSKKEILSFH 245 >UniRef50_Q3A4F2 Cluster: Putative transport system permease protein; n=1; Pelobacter carbinolicus DSM 2380|Rep: Putative transport system permease protein - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 314 Score = 48.0 bits (109), Expect = 5e-04 Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 8/105 (7%) Query: 101 KTRSGRVVL-TAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 K R+ R+ + TA G+ L KL F TGS ++ S I SL D V + I ++ Sbjct: 8 KIRAARISMATATGLT----LLKLVTGFLTGSMAVLSSAIDSLLDIVMSVANFLAIRQAE 63 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHG---VTGI 201 Q DP HP+G+ +++++ + I G + + G +TGI Sbjct: 64 QPPDPKHPFGHGKFETLATIVQALAIGLSGGWVCYESGRRLLTGI 108 >UniRef50_Q01VH6 Cluster: Cation diffusion facilitator family transporter precursor; n=1; Solibacter usitatus Ellin6076|Rep: Cation diffusion facilitator family transporter precursor - Solibacter usitatus (strain Ellin6076) Length = 291 Score = 48.0 bits (109), Expect = 5e-04 Identities = 36/135 (26%), Positives = 63/135 (46%), Gaps = 5/135 (3%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 RV + + ++G L K+ A S ++ ++ + S AD + + +G+ + + AD + Sbjct: 6 RVAVAGMLVSGALALIKIFAGLAGNSTAVVADGLESAADVIASGFVLFGLTIAARPADDN 65 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 HPYG+ + ++ L+ +G G G G L QP A FV+G V+S Sbjct: 66 HPYGHGRVETLTGLV--IGFVLTGGGALISWGSLRRLG-QPTEPL--AAFVIGPLVLSLF 120 Query: 226 ATLMVALSAIRKGAR 240 A + +A R G R Sbjct: 121 AKMGLAAMKFRYGKR 135 >UniRef50_A1WYJ4 Cluster: Cation diffusion facilitator family transporter; n=3; Ectothiorhodospiraceae|Rep: Cation diffusion facilitator family transporter - Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospirahalophila (strain DSM 244 / SL1)) Length = 389 Score = 48.0 bits (109), Expect = 5e-04 Identities = 68/285 (23%), Positives = 115/285 (40%), Gaps = 29/285 (10%) Query: 86 MSHTRSKDNVEEVGLKTRSGRVVLTAIGIN---GCNFLFKLCAWFYTGSHSLFSECIHSL 142 MS RS + E + + RV L IN GC K+ A + S +L + +HSL Sbjct: 1 MSGRRSATAIAEDPARAKR-RVTLIGGVINLFLGCG---KIAAGWLGQSQALVVDGVHSL 56 Query: 143 ADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGIL 202 +D + ++ Q AD DHPYG+ + ++ G + V +G Y V +L Sbjct: 57 SDLASDALVYVAAAYGSQEADSDHPYGHARIETAATAGIGAVLLLVAAGF-IYDAVQRLL 115 Query: 203 -DPQPLHDFYWAYF--VLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVN 259 P+ L W L V+ EG A R + + + + + SD + Sbjct: 116 ITPESLWVPGWLALGVALASLVIKEGLYHYTRWVAYRAHSNLIHANAWHH---RSDALSS 172 Query: 260 VVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVG 319 VV++ + GV++ G P DA+ +I+V +L V +V LV Sbjct: 173 VVVV---GGIVGVLL-----------GLPWLDAVAAIVVAVMLAHVGITFAWRSVCELVD 218 Query: 320 RSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSN-LIRYKAEVD 363 + Q+ I ++ +R +H ++ + LI +VD Sbjct: 219 TGLDPAQVAHIERLVSEIDGVRDVHGLRSRHMAEEALIDLHIQVD 263 >UniRef50_A1HSL0 Cluster: Cation diffusion facilitator family transporter; n=1; Thermosinus carboxydivorans Nor1|Rep: Cation diffusion facilitator family transporter - Thermosinus carboxydivorans Nor1 Length = 295 Score = 48.0 bits (109), Expect = 5e-04 Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 3/79 (3%) Query: 100 LKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 LK R+ R+ + + N L KL FY+G+ S+ SE HS D + LI Y + KS Sbjct: 7 LKQRTARLSVIS---NTLLVLLKLVVGFYSGAVSIISEAAHSGVDLLAALIAYYAVRKSS 63 Query: 160 QMADPDHPYGYTNMRYVSS 178 Q D H YG+ +S+ Sbjct: 64 QPPDAQHAYGHGKFENLSA 82 >UniRef50_Q5LTM6 Cluster: Cation efflux system protein; n=13; Alphaproteobacteria|Rep: Cation efflux system protein - Silicibacter pomeroyi Length = 320 Score = 47.6 bits (108), Expect = 6e-04 Identities = 34/124 (27%), Positives = 62/124 (50%), Gaps = 4/124 (3%) Query: 111 AIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQM-ADPDHPYG 169 AI +N L ++ +GS +L ++ +H+ +D V LI+A+G + + AD YG Sbjct: 38 AIAVNMVLTLAQVVGGLLSGSLALIADALHNFSDAV-ALIIAFGARRIARRPADARMSYG 96 Query: 170 YTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLM 229 Y +++LI+ + + L Y G+ LDPQP+ D + ++ A+V + T Sbjct: 97 YGRAEVIAALINYTTLIVLALYL-VYEGIMRFLDPQPI-DGWLVVWIAALALVIDLVTAA 154 Query: 230 VALS 233 + S Sbjct: 155 LTWS 158 >UniRef50_Q6QSW0 Cluster: Cation efflux facilitator; n=1; Enterococcus faecium|Rep: Cation efflux facilitator - Enterococcus faecium (Streptococcus faecium) Length = 307 Score = 47.6 bits (108), Expect = 6e-04 Identities = 28/107 (26%), Positives = 51/107 (47%), Gaps = 6/107 (5%) Query: 118 NFLFKLCAWFYTG---SHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMR 174 NF+F + +F+ S S+ S+ +H L D+++ + S + D +GY Sbjct: 32 NFIFSMIEFFFGSLFNSVSIMSDAVHDLGDSISIGFAWFFQGYSEKQQDEQFTFGYNRFS 91 Query: 175 YVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLH--DFYWAYFVLGG 219 + +LI+GV + GS Y + ++DPQP++ +W V G Sbjct: 92 LLGALITGV-VLIGGSFFMIYRSIPRLIDPQPVNYSGMFWLSLVAIG 137 >UniRef50_Q03ZB0 Cluster: Co/Zn/Cd efflux system component; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Co/Zn/Cd efflux system component - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 305 Score = 47.6 bits (108), Expect = 6e-04 Identities = 49/216 (22%), Positives = 94/216 (43%), Gaps = 11/216 (5%) Query: 109 LTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPY 168 L I +N L +L S +LF++ H+L+D + +I + A H Y Sbjct: 16 LIGISLNMIFVLSELVFAKLAHSTALFADAFHNLSDVLALMIAWLAVVVFGLQATKRHTY 75 Query: 169 GYTNMRYVSSLISGV-GIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGAT 227 G+ NM ++S+ + + IF V + FY + ++ P+ W V V + G Sbjct: 76 GWHNMSILASVFNTILLIFAVIT--IFYESIRNLILPENTVTTGWLVMV----VAAVGIV 129 Query: 228 LMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGN 287 + A + + K + + + + + + + LL D GVI+A + Q TG Sbjct: 130 INFATAMLFKASGVPDEHGHHHEQDLNAKTAYIHLLADAGVSVGVIIAG---LLIQVTGW 186 Query: 288 PLPDALGSILVGTILGGVASFIILSNVGALVGRSIP 323 + D + S+++G I+ V S+ ++ + L +P Sbjct: 187 HVIDPIVSMIIGVII-AVTSWPVMKSTFNLALNGVP 221 >UniRef50_Q8KEZ4 Cluster: Cation efflux family protein; n=6; Chlorobiaceae|Rep: Cation efflux family protein - Chlorobium tepidum Length = 463 Score = 47.2 bits (107), Expect = 8e-04 Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 4/142 (2%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 V L+++ + KL TGS + SE HS D + + + S + AD H Sbjct: 11 VALSSVAASLLLTAMKLVVGLMTGSIGILSEAAHSAIDFGAAALTWFAVRISDKPADKKH 70 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGA 226 YG+T + VS+LI G+ + S Y VT +L + W + + ++S Sbjct: 71 HYGHTKIESVSALIE-TGLLILTSVWIIYEAVTRLLSGTTEIEVTW--YAIAVIIISIIV 127 Query: 227 TLMVALSAIRKGAREANMSLYE 248 + A SA++K A+E E Sbjct: 128 DISRA-SALKKVAKETKSQALE 148 >UniRef50_A7HL40 Cluster: Cation diffusion facilitator family transporter; n=1; Fervidobacterium nodosum Rt17-B1|Rep: Cation diffusion facilitator family transporter - Fervidobacterium nodosum Rt17-B1 Length = 324 Score = 47.2 bits (107), Expect = 8e-04 Identities = 59/242 (24%), Positives = 115/242 (47%), Gaps = 27/242 (11%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHK-SVQMADPD 165 VVL GI F+ + A GS +L S+ +H+L+D ++ +ILAY HK S++ A+ Sbjct: 43 VVLLNFGITLAEFIGGMLA----GSLALVSDSMHNLSDALS-IILAYFAHKISLRGANKG 97 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 +GY + +S+ ++ V + + + L V ++ P+ +H ++G + Sbjct: 98 KTFGYGRAKIISAFVNSVTLMVI-TVLLIKEAVLRLIKPEFVHSD--TVIIVGTIGLIAN 154 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYT 285 M+ L KG E ++++ + +L + ++VA V+ A ++ YT Sbjct: 155 ILSMIFL----KGHSEKDINIKSAYLH--------MLGDAFSSVAVVLGAILIKYLNIYT 202 Query: 286 GNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHE-QLDEINSVLERDFMIRAIH 344 +P+ +I + +G + I++ ++ L+ +S PH +DEI LE I +H Sbjct: 203 IDPIL----TIFIALYIGKESFEILIKSLNVLM-QSTPHNIDVDEIIKRLENISEIENVH 257 Query: 345 DV 346 V Sbjct: 258 HV 259 >UniRef50_A1VH99 Cluster: Cation diffusion facilitator family transporter; n=2; Desulfovibrio vulgaris subsp. vulgaris|Rep: Cation diffusion facilitator family transporter - Desulfovibrio vulgaris subsp. vulgaris (strain DP4) Length = 303 Score = 47.2 bits (107), Expect = 8e-04 Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 4/141 (2%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R + ++ C + K+ A+ T S +L S+ S+ + V + ++ + D Sbjct: 7 RAIALSLVCGVCILVLKMLAYLVTDSAALMSDAFESIVNVVASAFTMWTLYVAQTPPDRR 66 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 HPYG+ + + + G + G+ I++P+ + LG +VV+ Sbjct: 67 HPYGHGRVEFFAVFFEGALVIVAALGI-IVAAAPRIIEPRAMVQL---DIGLGLSVVASA 122 Query: 226 ATLMVALSAIRKGAREANMSL 246 L++ L IR G RE ++L Sbjct: 123 INLVLGLYLIRVGRREDRLAL 143 >UniRef50_Q311T6 Cluster: Cation diffusion facilitator family transporter; n=1; Desulfovibrio desulfuricans G20|Rep: Cation diffusion facilitator family transporter - Desulfovibrio desulfuricans (strain G20) Length = 314 Score = 46.8 bits (106), Expect = 0.001 Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 8/184 (4%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 RV + +N FK+ A S ++ ++ IHSL+D V +++ G+ AD + Sbjct: 18 RVTWIGLWLNLALAAFKIMAGTAGHSRAVVADGIHSLSDLVTDVVVLVGVRFWSAPADEE 77 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYF--VLGGAVVS 223 HP+G+ M + +++ +G+ G+ + + + +H F + VV Sbjct: 78 HPHGHQRMETMVTVV--IGLLLAGAAVGIAWDAIAAMGRESVHRRGAVAFGAAVLSIVVK 135 Query: 224 EGA---TLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMA 280 EG TL A A R A EAN + SS P+ V L GV A + Sbjct: 136 EGLYRWTLRAARKA-RSSALEANAWHHRTDALSSIPAAAAVGLAWFVPAWGVADLAGALV 194 Query: 281 ISQY 284 ++ + Sbjct: 195 VAVF 198 >UniRef50_A6CU38 Cluster: Cation efflux family protein; probable cobalt-zinc-cadmium resistance protein; n=1; Bacillus sp. SG-1|Rep: Cation efflux family protein; probable cobalt-zinc-cadmium resistance protein - Bacillus sp. SG-1 Length = 308 Score = 46.8 bits (106), Expect = 0.001 Identities = 41/168 (24%), Positives = 72/168 (42%), Gaps = 7/168 (4%) Query: 131 SHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGS 190 S +L ++ +HS +D L + G+ + Q D DHPYG+ ++++I V +F VG Sbjct: 37 SKALIADAVHSASDVAGSLAVYIGLRAAKQPPDDDHPYGHGKAESIAAIIVAVLLFLVGI 96 Query: 191 GLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYV 250 + + P Y V+ G VV E + + K + + + Y Sbjct: 97 EIG-KSSIESFFHPISPPTSIAIYAVIFGIVVKE--AMFQYKYKLGKKLKSDALIVNAYE 153 Query: 251 MRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILV 298 RS S L+ AA+ G ++ + +Y G+P+ S+LV Sbjct: 154 HRSDVYSSIAALVGIGAAMLGGVLGIGWL---EY-GDPVAGVFVSLLV 197 >UniRef50_A3CRV2 Cluster: Cation diffusion facilitator family transporter; n=1; Methanoculleus marisnigri JR1|Rep: Cation diffusion facilitator family transporter - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 305 Score = 46.8 bits (106), Expect = 0.001 Identities = 26/109 (23%), Positives = 54/109 (49%), Gaps = 4/109 (3%) Query: 99 GLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKS 158 G K R R+ + + +N L K+ GS S+ ++ HS D+++ +I ++ + Sbjct: 20 GRKVR--RIFIIVLALNLAVALAKVVFGLLAGSVSMVADAFHSGFDSLSNVIGIVALYFA 77 Query: 159 VQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSF--YHGVTGILDPQ 205 + DP+HPYG+ + + +L+ G + G+ + YH + + P+ Sbjct: 78 GKPPDPEHPYGHGKIETLGTLVIGAMLLLTAGGILYEGYHRLVEAVAPE 126 >UniRef50_Q9KEY7 Cluster: Cation efflux system; n=11; Bacillus|Rep: Cation efflux system - Bacillus halodurans Length = 307 Score = 46.4 bits (105), Expect = 0.001 Identities = 21/76 (27%), Positives = 39/76 (51%) Query: 114 INGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNM 173 +NG L K + +GS +L ++ HS +D + + G+ + + D DHPYG+ Sbjct: 18 VNGLLALMKGVIGWLSGSRALIADAAHSASDVAGSIAVLAGLRTAKKPPDADHPYGHGKA 77 Query: 174 RYVSSLISGVGIFCVG 189 V+++I + + VG Sbjct: 78 ENVATIIVAILLIVVG 93 >UniRef50_Q57BV0 Cluster: Cation efflux family protein; n=9; Rhizobiales|Rep: Cation efflux family protein - Brucella abortus Length = 302 Score = 46.4 bits (105), Expect = 0.001 Identities = 54/227 (23%), Positives = 102/227 (44%), Gaps = 17/227 (7%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K A+ TGS +L+S+ + S+ + + + + I S AD +HP+G+ Y+S+++ Sbjct: 25 KYVAYALTGSVALYSDALESIVNVIAAIGAWWAIRVSYLPADDNHPFGHHKAEYISAVVE 84 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGARE 241 GV + V + L F + P+ L + + LG + + + A IR G + Sbjct: 85 GV-LITVAALLIFREAWFALETPRMLDE---PWLGLGINMAAAAINGLWATLLIRTGRKF 140 Query: 242 ANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTI 301 + +L +D ++ D AGV+V + + TG + D L +ILV Sbjct: 141 RSPAL------EAD---GKHIMTDVFTSAGVLVGLVGVVV---TGWSVLDPLLAILVAIN 188 Query: 302 LGGVASFIILSNVGALVGRSI-PHEQLDEINSVLERDFMIRAIHDVK 347 + +I S+V L+ ++ P E++ N + +HD+K Sbjct: 189 ILWQGWHVINSSVQGLMDIAVEPTEEMRIRNVISANAGGAIEVHDLK 235 >UniRef50_Q2RHV4 Cluster: Cation diffusion facilitator family transporter; n=2; Bacteria|Rep: Cation diffusion facilitator family transporter - Moorella thermoacetica (strain ATCC 39073) Length = 308 Score = 46.4 bits (105), Expect = 0.001 Identities = 58/241 (24%), Positives = 103/241 (42%), Gaps = 26/241 (10%) Query: 100 LKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 ++TR+ RV +I N L KL ++ S S+ SE IHS D V I + + ++ Sbjct: 3 VRTRAARV---SIFSNIILVLGKLGIGYWMHSVSVMSEAIHSGLDLVAAAIAYFSVREAS 59 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGG 219 + AD +H YG+ + +S I + IF + Y + F+ G Sbjct: 60 KPADAEHRYGHGKIENISGTIEALLIFLAALWI-IYEAI--------------KRFISGS 104 Query: 220 AVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAV-AGVIVAASC 278 +SE T + A+ GA N + Y+ R + + ++ L D + V +A Sbjct: 105 HAISEPLTGV----AVMGGAGVVNYLVSRYLFRVAKDTDSIALEADAWHLRTDVYTSAGV 160 Query: 279 M---AISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLE 335 M A +TG D L +++V ++ A + + L+ S+P E+ + I ++ Sbjct: 161 MLGLAALYFTGFQWLDPLVALVVAAMIIKAAYHLTREAMLPLMDVSLPAEEEEVIKEIIA 220 Query: 336 R 336 R Sbjct: 221 R 221 >UniRef50_A3ZLV0 Cluster: Putative uncharacterized protein; n=1; Blastopirellula marina DSM 3645|Rep: Putative uncharacterized protein - Blastopirellula marina DSM 3645 Length = 282 Score = 46.0 bits (104), Expect = 0.002 Identities = 19/59 (32%), Positives = 36/59 (61%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSS 178 + KL GS +L S+ I+SL D++ +++ +G+ + + AD +HPYG+T V++ Sbjct: 9 IVKLAGGVLGGSFALISDAINSLGDSLTSIVVIFGLWYAQRPADEEHPYGHTRAEAVAA 67 >UniRef50_A3EVG9 Cluster: Putative Co/Zn/Cd cation transporter; n=1; Leptospirillum sp. Group II UBA|Rep: Putative Co/Zn/Cd cation transporter - Leptospirillum sp. Group II UBA Length = 315 Score = 46.0 bits (104), Expect = 0.002 Identities = 54/218 (24%), Positives = 91/218 (41%), Gaps = 22/218 (10%) Query: 128 YTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFC 187 ++GS SL S+ H++AD + L L + + +PYGY ++ + VG+ Sbjct: 53 FSGSVSLLSDAFHNVADGLTGLPLWLAFSLAAKRPSLRYPYGYGKFEDLAGIFI-VGLIF 111 Query: 188 VGSGLSFYHGVTGILDPQPLHDFYWAYFV-LGGAVVSEGATLMVALSAIRKGAREANMSL 246 +G+S PQ H W L G + +E VA IR G + ++SL Sbjct: 112 FSAGVSLVRSGEKFFHPQVFHHPGWVTLASLTGFLANEA----VAFLRIRAGRKTGSISL 167 Query: 247 YEYVMRSS-DPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGV 305 + D ++ +L VAG + TG+PL D + I++G + + Sbjct: 168 VADGQHARVDGFTSLTVL---VGVAGSV-----------TGHPLWDPVVGIVLGISVLWI 213 Query: 306 ASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAI 343 A ++ +VG + I E L+ I IRA+ Sbjct: 214 A-LRMMRDVGLHLSDGIEPETLEIIRKAASDSCAIRAV 250 >UniRef50_A1TZF9 Cluster: Cation diffusion facilitator family transporter; n=2; Marinobacter|Rep: Cation diffusion facilitator family transporter - Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8)(Marinobacter hydrocarbonoclasticus (strain DSM 11845)) Length = 387 Score = 46.0 bits (104), Expect = 0.002 Identities = 53/270 (19%), Positives = 111/270 (41%), Gaps = 19/270 (7%) Query: 87 SHTRSKDNVEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTV 146 SH R ++N+E K + RV + + ++ + K+ S +L + IHS D Sbjct: 8 SHQR-QNNLESE--KHAATRVTIIGMILDAVLGIIKVIGGTLFNSQALLVDGIHSFTDVA 64 Query: 147 NQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQP 206 + ++ + S + D D+PYG+ + + +L+ G + VG+ L+ + + +L + Sbjct: 65 SDWVVLAVMRLSRKEPDADYPYGHQRIETLGTLVLGSILIAVGAALA-WENILRLLSGE- 122 Query: 207 LHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDT 266 A V G V+ A + I + R M + SD + T Sbjct: 123 ------AQLVPGWPVLVAAAASVAGKEWIYRYTRHVGMKI------RSDLIIANAWHSRT 170 Query: 267 AAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQ 326 A + V+V S I G D + ++L+ I+ + +V LV + + Sbjct: 171 DAFSSVVVLVS--TIGAMLGFVWLDVVAAVLIAAIIVHIGWKFTWDSVKELVDTGLSEDD 228 Query: 327 LDEINSVLERDFMIRAIHDVKGIDIGSNLI 356 + ++ +R +H+++ +G +++ Sbjct: 229 TRMLKTIALETDGVRNVHELRSRRMGHDIL 258 >UniRef50_Q5L2G4 Cluster: Cation efflux transporter; n=5; Bacillaceae|Rep: Cation efflux transporter - Geobacillus kaustophilus Length = 315 Score = 45.6 bits (103), Expect = 0.003 Identities = 73/320 (22%), Positives = 133/320 (41%), Gaps = 29/320 (9%) Query: 88 HTRSKDNVEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVN 147 H D+ E K + +++TA GI L + T S +L S+ H L+D + Sbjct: 19 HGHHHDHSREGNKKGLTIALLITA-GI----MLLEFFGGLITNSLALLSDSGHMLSDASS 73 Query: 148 QLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPL 207 ++ I + + A P+ YG+ +++L +GV +F + +G + + +P + Sbjct: 74 LVLSLVAIWFATKPASPNKTYGFYRFEILAALFNGVTLFVI-AGFIIWEAIERFYNPPTV 132 Query: 208 HDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTA 267 A + A L+ A + ++KG + N++L S + ++ D Sbjct: 133 ASGSMMLI----ASIGLFANLLSAWALMKKGDVKNNVNL---------RSAYLHVIGDAL 179 Query: 268 AVAGVIVAASCM-AISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALV-GRSIPHE 325 G I+A M S Y +P+ SILV ++ A +I V L+ G I + Sbjct: 180 GSVGAIIAGLVMWLFSWYVADPII----SILVALLILKGAWGVIKHTVHILMEGTPITID 235 Query: 326 QLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLNALLED 385 Q +E+ LE + +HD+ I S L + + ++ L+ + +ED Sbjct: 236 Q-NEVKKALESIEGVINVHDLHIWTITSGLDSLSCHILIEDHQDSQKVLQ--EAIHFIED 292 Query: 386 MKKID-TIDDVETFLLKHGE 404 KI +ET + HGE Sbjct: 293 HFKIQHATIQIETSQIHHGE 312 >UniRef50_Q1NQB8 Cluster: Cation efflux protein; n=2; delta proteobacterium MLMS-1|Rep: Cation efflux protein - delta proteobacterium MLMS-1 Length = 304 Score = 45.6 bits (103), Expect = 0.003 Identities = 32/113 (28%), Positives = 57/113 (50%), Gaps = 11/113 (9%) Query: 85 EMSHTRSKDNVEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFY---TGSHSLFSECIHS 141 E HT +D + R GR+ T IGI G N L L +GS +L ++ +HS Sbjct: 5 EQDHTIGQDE------RYRQGRLA-TWIGIIG-NVLLALLKGVIGALSGSLALIADAVHS 56 Query: 142 LADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSF 194 L+D ++ L++ G+ S AD +H YG+ +++ I + + +G+++ Sbjct: 57 LSDVLSSLVVLAGLKYSQLPADANHHYGHAKAESIAAKIVAIMLLVAAAGIAW 109 >UniRef50_A6LXL8 Cluster: Cation diffusion facilitator family transporter; n=3; Clostridiales|Rep: Cation diffusion facilitator family transporter - Clostridium beijerinckii NCIMB 8052 Length = 298 Score = 45.6 bits (103), Expect = 0.003 Identities = 24/69 (34%), Positives = 34/69 (49%) Query: 115 NGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMR 174 N KL TGS S+ SE IHS D + +I + + S + AD HPYG+ + Sbjct: 15 NSILITLKLIVGLATGSVSIISEAIHSTMDLLAAIIAFFSVKISDKPADDIHPYGHGKIE 74 Query: 175 YVSSLISGV 183 VS +I + Sbjct: 75 NVSGVIEAI 83 >UniRef50_A1SZS2 Cluster: Iron and zinc efflux system protein; n=4; Gammaproteobacteria|Rep: Iron and zinc efflux system protein - Psychromonas ingrahamii (strain 37) Length = 318 Score = 45.6 bits (103), Expect = 0.003 Identities = 65/295 (22%), Positives = 119/295 (40%), Gaps = 24/295 (8%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 L KL AW TGS S+ + SL D +I I ++Q AD +H +G+ ++ L Sbjct: 30 LVKLIAWVMTGSASILATLTDSLMDVTTSIINLLAIKIALQPADDEHRFGHGKAESLAGL 89 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 I SG S Y GI H +G + S T+++ Sbjct: 90 AQAAFI----SGTSMYLMFNGISALVNGHQISATNVGIGVMIFSVIVTILL--------- 136 Query: 240 REANMSLYEYVMRSSDP-SVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILV 298 ++ Y+++ +D ++ L +A + ++ Y G D + +I V Sbjct: 137 ----VAFQSYIVKKTDSMAIRADSLHYRTDIAMNGAVLLALILAGY-GWYWADGVFAIAV 191 Query: 299 G-TILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVK-GIDIGSNLI 356 IL G LS + AL+ + +P ++I +R +HD++ + + I Sbjct: 192 SFYILHGAWQIGRLS-IDALMDKQLPKSDEEKIVKTAYHIKGVRGVHDLRTRLSGNTKFI 250 Query: 357 RYKAEVDFDGRALTRSYLEKHDLNALLE-DMKKIDTIDDVETFLLKHGENIVDML 410 + E+D D ++L ++ + L LE D + D + ++ + E + D L Sbjct: 251 QLHLELD-DNQSLLEAHNKADQLEEALESDFPRADILIHLDPLSIVEEEKLNDKL 304 >UniRef50_A0AWY3 Cluster: Cation diffusion facilitator family transporter; n=14; Actinomycetales|Rep: Cation diffusion facilitator family transporter - Arthrobacter sp. (strain FB24) Length = 445 Score = 45.6 bits (103), Expect = 0.003 Identities = 53/250 (21%), Positives = 100/250 (40%), Gaps = 18/250 (7%) Query: 87 SHTRSKDNVEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTV 146 SH S + + T R + ++ I L +L ++GS +L ++ IH+ +D + Sbjct: 122 SHDASDSIDDALEASTEGIRALKISLFILLGTTLLQLIVVLFSGSVALLADTIHNFSDAL 181 Query: 147 NQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQP 206 L L + A H YGY ++ L V + + + ++ + + + P P Sbjct: 182 TALPLWVAFILGRRAASRRHTYGYGKSEDLAGLFI-VAVVALSAVVAAWQSIDRLFHPHP 240 Query: 207 LHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDT 266 L + +W V+ +V VA+ IR G + + +L + V D Sbjct: 241 LENLWW---VVAAGLVGFIGNEAVAVYRIRVGQKIGSAALV---------ADGVHARTDG 288 Query: 267 AAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQ 326 V+V A + + +P+ L S+ + +L G + ++G + I E Sbjct: 289 FTSLAVVVGAGGVMLGFPLADPIVGLLISVAIIILLWGT-----VRSIGRRLMDGIEPEL 343 Query: 327 LDEINSVLER 336 LD + LER Sbjct: 344 LDRAQTALER 353 >UniRef50_Q5ZR77 Cluster: Putative uncharacterized protein R02F11.3; n=3; Caenorhabditis|Rep: Putative uncharacterized protein R02F11.3 - Caenorhabditis elegans Length = 489 Score = 45.6 bits (103), Expect = 0.003 Identities = 73/331 (22%), Positives = 136/331 (41%), Gaps = 23/331 (6%) Query: 72 VFTVKRRLRDYRRE-MSHTRSKD-NVEEV--GLKTRSGRVVLTAIGINGCNFLFKLCAWF 127 +F V R R+ R++ M T +++ +V+E + R+ + +N + K+ A Sbjct: 155 IFDVPRSPRNPRKKPMERTDTEEKSVDEKKDDESNTAARMANITLAVNFLLMIAKVVASV 214 Query: 128 YTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD-HPYGYTNMRYVSSLISGVGIF 186 +GS S+ S + S+ D + L+++ + ++ DP +P G T + +S ++ V I Sbjct: 215 LSGSMSIISSMVDSVVDITSGLVISLS-ERMIKKRDPYLYPRGRTRLEPLSLILISV-IM 272 Query: 187 CVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSL 246 + S V GI D H L G + + I +SL Sbjct: 273 GMASIQLIIASVRGIHDGIQFH--------LYGIGEEPKLNVTITSVVIMVSTVLVKLSL 324 Query: 247 YEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVA 306 Y + R +PSVNV+ ++ VA C + D G+I+V + Sbjct: 325 YLFCKRYKEPSVNVLAMDHRNDCISNTVALICAWLGTKYSYYF-DPAGAIVVSMYILYTW 383 Query: 307 SFIILSNVGALVGRSIPHEQLDEINSV-LERDFMIRAIHDVKGIDIGSNLIRYKAEVDFD 365 ++ L G++ E ++ I V L+ D I I V GS + + + D Sbjct: 384 VQTGREHLAKLSGKTAEPEFINRIIKVCLDHDARISHIDTVYVYHFGSKFL-VEVHIVLD 442 Query: 366 GRALTRSYLEKHDLNALLEDMKKIDTIDDVE 396 + + E HD++ L+ I+++ +VE Sbjct: 443 ENMILK---ESHDISETLQ--SNIESLPEVE 468 >UniRef50_Q6MCR1 Cluster: Putative cation efflux system protein; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Putative cation efflux system protein - Protochlamydia amoebophila (strain UWE25) Length = 313 Score = 45.2 bits (102), Expect = 0.003 Identities = 47/210 (22%), Positives = 92/210 (43%), Gaps = 20/210 (9%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 +F+L S +LF + I L D ++ + L I + + D DHP+G+ + L Sbjct: 41 VFELFGVALINSSTLFLDAISGLMDVLSTIFLIICIKLARKPPDEDHPFGHGRYEPLGGL 100 Query: 180 ISGVGIFCVGSGLSFYHGVTGILD--PQP-LHDFYWAYFVLGGAVVSEGATLMVALSAIR 236 + G+ + +G+ + + V G + PQP LH WA+ A++ L + I Sbjct: 101 LIGLILIFIGA-IMLFQQVNGFIQEAPQPFLHP--WAWIFPATAMI----LLEICYQLIF 153 Query: 237 KGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSI 296 + A+ N + + + L A +I AA + +++G + D +G+I Sbjct: 154 RTAKNENSP----ALAADAVHYRIDGLTSLLATLTLIAAA---LVPEWSG--IVDHIGAI 204 Query: 297 LVGTILGGVASFIILSNVGALVGRSIPHEQ 326 L+ + G+ F N L + +P+++ Sbjct: 205 LIALFMIGLGVFAARENFNQLTDK-VPNQE 233 >UniRef50_Q2AI61 Cluster: Cation efflux protein; n=1; Halothermothrix orenii H 168|Rep: Cation efflux protein - Halothermothrix orenii H 168 Length = 292 Score = 45.2 bits (102), Expect = 0.003 Identities = 57/254 (22%), Positives = 108/254 (42%), Gaps = 23/254 (9%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 +V +I IN + K+ S +L ++ +HS++D + +++ I S AD Sbjct: 12 KVSFISIVINIILSVAKIFIGISFASKALLADGVHSVSDIASTVVVLISIKFSQNPADER 71 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 HPYG+ + + + +G+ + +GL+ G + + G V Sbjct: 72 HPYGHGKAEQIGTAL--LGLMLLITGLTLIKDTAGNM-------------ITGEITVPGQ 116 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDT---AAVAGVIVAASCMAIS 282 TL +AL +I ++EA LY+Y ++ + L+ D + A VAA Sbjct: 117 ITLWIALISII--SKEA---LYQYTVKIGKKINSKGLVADAHHHRSDALSSVAALAGIAG 171 Query: 283 QYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRA 342 G P D L ++V ++ ++ II V L+ +++ +I + E ++ Sbjct: 172 ARLGYPFLDPLAGLIVALLIIKISIEIIKEAVHELMDGIPDEDKIVKIRKIAENVSGVKD 231 Query: 343 IHDVKGIDIGSNLI 356 I D+K G +LI Sbjct: 232 IGDIKIRSYGPHLI 245 >UniRef50_A0YFC6 Cluster: Cation transporter, cation diffusion facilitator (CDF) family protein; n=2; Gammaproteobacteria|Rep: Cation transporter, cation diffusion facilitator (CDF) family protein - marine gamma proteobacterium HTCC2143 Length = 293 Score = 45.2 bits (102), Expect = 0.003 Identities = 22/65 (33%), Positives = 35/65 (53%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R++L +N F+ KL TGS ++ + IHS+ D +N +I + S AD + Sbjct: 19 RILLIEGSVNLLVFVAKLIVGLTTGSLAILGDAIHSMTDVINNVIAWSVVRLSHAPADRE 78 Query: 166 HPYGY 170 HPYG+ Sbjct: 79 HPYGH 83 >UniRef50_A0V364 Cluster: Cation diffusion facilitator family transporter precursor; n=1; Clostridium cellulolyticum H10|Rep: Cation diffusion facilitator family transporter precursor - Clostridium cellulolyticum H10 Length = 285 Score = 45.2 bits (102), Expect = 0.003 Identities = 38/168 (22%), Positives = 76/168 (45%), Gaps = 9/168 (5%) Query: 107 VVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH 166 V + I N KL A F + S ++ ++ +S D ++ G + + D DH Sbjct: 10 VAVFGIVANVFLLFIKLAAGFISRSQAMIADGFNSAGDVFASVMTLVGNSIASKPEDSDH 69 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGA 226 PYG+ Y+ S+I + + V S F ++ I++ F ++F++ A+++ Sbjct: 70 PYGHGKAEYIFSMIISISLMFV-SFTIFKSSLSSIINKA---SFTVSWFLIATAIITIAI 125 Query: 227 TLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIV 274 L + + R G R N+ V+ +S+ N V + + + G+I+ Sbjct: 126 KLSLFIYTSRIGKRMDNL----LVIANSEDHRNDVFV-TSGTILGIIM 168 >UniRef50_O27240 Cluster: Possible cation transporter; n=1; Methanothermobacter thermautotrophicus str. Delta H|Rep: Possible cation transporter - Methanobacterium thermoautotrophicum Length = 407 Score = 45.2 bits (102), Expect = 0.003 Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 3/120 (2%) Query: 127 FYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIF 186 + +G+ +L ++ IHS AD + + G+ S + D PYGY + + SL+ V I Sbjct: 35 YLSGNIALIADAIHSFADVFSSAAVFIGLKLSQRKPDELFPYGYHRIETLVSLLVSVLII 94 Query: 187 CVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSL 246 G ++ + + IL+ P + A L +++S G + +A +R G R + +L Sbjct: 95 ITGLEIT-WDSIIYILN--PASEVSMATASLAVSLISIGVSYAIAFYKVRVGRRIGSTAL 151 >UniRef50_Q1AYG3 Cluster: Cation diffusion facilitator family transporter; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Cation diffusion facilitator family transporter - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 314 Score = 44.8 bits (101), Expect = 0.005 Identities = 27/121 (22%), Positives = 55/121 (45%), Gaps = 1/121 (0%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R + A+ I + + F TGS +L ++ H L+D + + + + S + P+ Sbjct: 18 RSLAAALAITASYTVAEAVGGFLTGSLALLADAAHMLSDNFSLGLALFALWLSSRPPTPE 77 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 +GY +++L +GV + V + FY +L+P+ + + A G +V+ Sbjct: 78 RSFGYKRAEILAALFNGVTLVAVSLWI-FYEAYRRLLEPREVMGGWVAAVAAAGLLVNAA 136 Query: 226 A 226 A Sbjct: 137 A 137 >UniRef50_A1VZU0 Cluster: Cation efflux family protein; n=12; Campylobacter|Rep: Cation efflux family protein - Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176) Length = 295 Score = 44.8 bits (101), Expect = 0.005 Identities = 50/228 (21%), Positives = 101/228 (44%), Gaps = 16/228 (7%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 L K +GS ++ S I SL D + KS Q A+ ++ +G++ + + L Sbjct: 20 LVKFIVGLTSGSVAVLSSAIDSLMDFAISAFNFLALKKSSQKANENYNFGFSKIEALMGL 79 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 + GV I VG + FY + I + + D + +V+ A++ L++ L+ + K Sbjct: 80 LEGVFIVGVGIFI-FYESILKIYYKEEIKDLNSSIYVMIFALIMT-FFLVLFLNYVAKKT 137 Query: 240 REANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVG 299 + + + + +D N A G +V + +T + DA+ I++ Sbjct: 138 KSLIIE-SDALHYKTDCLTN-------ACTLGALV------LIYFTNLHIIDAIFGIVIS 183 Query: 300 TILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVK 347 A II + L+ ++P EQ+D+I +++ + I + H++K Sbjct: 184 LYTAFSAFKIIKKALAFLMDEALPKEQVDKICTLISNNPEIISYHELK 231 >UniRef50_P46348 Cluster: Uncharacterized transporter yeaB; n=19; Bacillales|Rep: Uncharacterized transporter yeaB - Bacillus subtilis Length = 290 Score = 44.8 bits (101), Expect = 0.005 Identities = 27/101 (26%), Positives = 48/101 (47%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 KL + S +L ++ +++ D + + + G+ S + D DHPYG+ ++SLI+ Sbjct: 28 KLIIGYLFHSEALTADGLNNTTDIIASVAVLIGLRISQKPPDEDHPYGHFRAETIASLIA 87 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVV 222 + VG + F G + Q D A+ GGAV+ Sbjct: 88 SFIMMVVGLQVLFSAGESIFSAKQETPDMIAAWTAAGGAVL 128 >UniRef50_Q62FW4 Cluster: Cation efflux family protein; n=48; Proteobacteria|Rep: Cation efflux family protein - Burkholderia mallei (Pseudomonas mallei) Length = 396 Score = 44.4 bits (100), Expect = 0.006 Identities = 37/144 (25%), Positives = 65/144 (45%), Gaps = 5/144 (3%) Query: 131 SHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGS 190 S +L ++ +HSL+D V+ ++ S D DH YG++ V+S G + VG Sbjct: 44 SQALIADGVHSLSDLVSDFVVLLANRHSGAKPDADHNYGHSRYETVASFFLGAILIAVGV 103 Query: 191 GLSFYHG--VTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYE 248 G+ + G + + D P+H A V+ ++S+ L ++ R A + Sbjct: 104 GMLWRAGDRLVHLEDIPPVHASALAVAVV--VLLSKEGLFRYMLREAQR-VRSAMLVANA 160 Query: 249 YVMRSSDPSVNVVLLEDTAAVAGV 272 + RS S VV + ++AGV Sbjct: 161 WHARSDAASSLVVAIGIIGSLAGV 184 >UniRef50_Q3VS68 Cluster: Cation efflux protein; n=2; Chlorobiaceae|Rep: Cation efflux protein - Prosthecochloris aestuarii DSM 271 Length = 319 Score = 44.4 bits (100), Expect = 0.006 Identities = 51/248 (20%), Positives = 99/248 (39%), Gaps = 21/248 (8%) Query: 99 GLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKS 158 G K + G + A+ + G FL +L + +GS +L ++ H D I I S Sbjct: 33 GRKAKKG--LRFAVSVTGLIFLVELIGGWVSGSLALMADAGHMATDLFALSISYLAIRLS 90 Query: 159 VQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLG 218 + + YGY + +++LI+GV I C+ + I P+ + F Sbjct: 91 ARPSTKKRSYGYFRIEIIAALINGV-ILCITALFITIEAWKRISLPKEIDSAQMLVF--- 146 Query: 219 GAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASC 278 ++ A + A+ R+ N+ + + +L D A GV+ + Sbjct: 147 -GIIGLTANIASAIMLHREQKNSVNVK-----------AAYIHILSDLAGSVGVVAGSIL 194 Query: 279 MAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDF 338 +++++ T D++ S ++ ++ A II V L+ P + EI L Sbjct: 195 ISLTRIT---TIDSIISFIIAILIVQSALKIIREAVDVLMESVPPELDIQEIEEALLNFR 251 Query: 339 MIRAIHDV 346 + +HD+ Sbjct: 252 HVEGLHDL 259 >UniRef50_A3XRG5 Cluster: Cobalt/zinc/cadmium cation efflux pump protein; n=7; Bacteria|Rep: Cobalt/zinc/cadmium cation efflux pump protein - Leeuwenhoekiella blandensis MED217 Length = 304 Score = 44.4 bits (100), Expect = 0.006 Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 8/160 (5%) Query: 105 GRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADP 164 GR +L +IG+N L ++ +GS +L S+ +H+L+D ++ +I S + A Sbjct: 18 GRNLLISIGLNVLITLAQIIGGLISGSLALLSDAVHNLSDVISLIISYIAQRYSKKEAST 77 Query: 165 DHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPL-HDFYWAYFVLGGAVVS 223 +GY +++ ++ + + + L V L+PQ + D VLG +V+ Sbjct: 78 HKTFGYKRAEIIAAFVNAATLIVI-AVLLMKEAVERFLNPQAIASDLVIWLAVLG--IVA 134 Query: 224 EGATLMVALSAIRKGAREANM-SLYEYVMRSSDPSVNVVL 262 G ++++ L KG NM S Y +++ SV V++ Sbjct: 135 NGLSVLL-LQKDSKG--NMNMRSAYLHLLTDMMASVAVLV 171 >UniRef50_Q5D9U1 Cluster: SJCHGC08837 protein; n=1; Schistosoma japonicum|Rep: SJCHGC08837 protein - Schistosoma japonicum (Blood fluke) Length = 147 Score = 44.4 bits (100), Expect = 0.006 Identities = 19/41 (46%), Positives = 27/41 (65%) Query: 1 MRAMTEYLLKQSDLESLPKVLRRSPYESEPPITVYYRRDVE 41 +RA+ EY+L + DL+ LP+ RSPY +E V+ R DVE Sbjct: 105 LRALREYMLTKQDLDQLPRYYSRSPYGNETKTLVFLRSDVE 145 >UniRef50_Q8CNH2 Cluster: CzrB protein; n=3; Staphylococcus|Rep: CzrB protein - Staphylococcus epidermidis (strain ATCC 12228) Length = 323 Score = 44.0 bits (99), Expect = 0.008 Identities = 53/244 (21%), Positives = 105/244 (43%), Gaps = 17/244 (6%) Query: 102 TRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQM 161 T + +V++ + I L ++ F S +L S+ H L+D ++ + + + Sbjct: 25 TDNKKVLMFSFIIISLFMLVEIIGGFLANSLALLSDGFHMLSDAISLGVALIAFIYAEKH 84 Query: 162 ADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAV 221 A YGY +++L +GV +F + S + + L+P + F++ +V Sbjct: 85 ATKSKTYGYKRFEILAALFNGVTLFII-SIIIIIEAIRRFLEPPEVQS--KEMFII--SV 139 Query: 222 VSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAI 281 + ++VA+ + G N++ MR + V L D G IVA+ + Sbjct: 140 IGLMVNIIVAILMFKGGDTSHNLN-----MRGAFLHV----LGDLFGSVGAIVASLLIWG 190 Query: 282 SQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIR 341 +T + D + SILV I+ A I S++ L+ + L+ + + +D I+ Sbjct: 191 FNFT---IADPIASILVSLIILKSAYGISKSSLNILMEGTPNDIDLNAVIKAISKDERIQ 247 Query: 342 AIHD 345 +HD Sbjct: 248 NVHD 251 >UniRef50_Q5FQH9 Cluster: Cation efflux system protein; n=1; Gluconobacter oxydans|Rep: Cation efflux system protein - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 297 Score = 44.0 bits (99), Expect = 0.008 Identities = 22/87 (25%), Positives = 44/87 (50%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 +V +I ++ K A+ +GS +L S+ I ++ + V + + + + AD + Sbjct: 7 KVARASIVLSVVVLAIKYAAYVVSGSEALLSDAIETILNVVAAVGTLWAMSVAALPADDN 66 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGL 192 HPYG+ Y+S++I GV + G+ Sbjct: 67 HPYGHGKAEYLSAVIEGVLVVLTAIGI 93 >UniRef50_Q2BMX3 Cluster: Cation-efflux family protein; n=1; Neptuniibacter caesariensis|Rep: Cation-efflux family protein - Neptuniibacter caesariensis Length = 393 Score = 44.0 bits (99), Expect = 0.008 Identities = 47/230 (20%), Positives = 99/230 (43%), Gaps = 20/230 (8%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 + K+ S +L ++ +HSL+D ++ +++ + S + D +HP+G+ + + Sbjct: 27 IIKIFVGQVANSTALIADGVHSLSDLLSDILIVAILRISGKGPDREHPWGHGYFETIGTA 86 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYW-AYFVLGGAVVSEGATLMVALSAIRKG 238 I G + V +G Y G T + + L W A V G +++ + LS +K Sbjct: 87 ILGCLLIAV-AGAMAYEGATQLFSHRELLSPEWPALLVAGISILGKEWIFRYTLSIGKK- 144 Query: 239 AREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILV 298 SD + T A++ +IV +G D+L ++ V Sbjct: 145 -------------LKSDLLIANAWHSRTDALSSIIVFIG--VAGAMSGFEWLDSLATVAV 189 Query: 299 GTILGGVASFIILSNVGALVGRSIPHEQLDE-INSVLERDFMIRAIHDVK 347 ++ + + S++ LV ++P +++D+ +L D ++ +HD K Sbjct: 190 ALLIAKIGWDLSWSSLKQLVNTALPQDEIDKYCEQILAVDGVVN-VHDFK 238 >UniRef50_A6LZH5 Cluster: Cation diffusion facilitator family transporter; n=1; Clostridium beijerinckii NCIMB 8052|Rep: Cation diffusion facilitator family transporter - Clostridium beijerinckii NCIMB 8052 Length = 393 Score = 44.0 bits (99), Expect = 0.008 Identities = 17/76 (22%), Positives = 38/76 (50%) Query: 114 INGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNM 173 IN + ++ + S ++ ++ H+L D ++ L+ + + + AD HP+GY + Sbjct: 39 INSSILILEIVIGLFLNSIAITADAFHNLTDALSSLVTIFSFKLANRPADDKHPFGYGRI 98 Query: 174 RYVSSLISGVGIFCVG 189 Y+++ + I VG Sbjct: 99 EYITAFLFSCAILVVG 114 >UniRef50_A0LXC1 Cluster: CDF family cation efflux protein; n=3; Bacteria|Rep: CDF family cation efflux protein - Gramella forsetii (strain KT0803) Length = 295 Score = 44.0 bits (99), Expect = 0.008 Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 1/103 (0%) Query: 103 RSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMA 162 +SG+ + A +N + + Y S ++ S+ +H L D+++ Y KS Q A Sbjct: 9 QSGKNLKLAFFLNLAFTILEFIGGMYVNSIAIISDAVHDLGDSLSLGTSWYLDKKSKQGA 68 Query: 163 DPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQ 205 + +GY + +LI+ V + GS Y V IL+PQ Sbjct: 69 NAQFSFGYRRFSLLGALINSV-VLIAGSVYVIYEAVGRILEPQ 110 >UniRef50_Q81QV5 Cluster: Cation efflux family protein; n=19; Firmicutes|Rep: Cation efflux family protein - Bacillus anthracis Length = 296 Score = 43.6 bits (98), Expect = 0.010 Identities = 58/244 (23%), Positives = 106/244 (43%), Gaps = 21/244 (8%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K+ + T S +L ++ +++L D L + G+ S + DPDHPYG++ ++SL++ Sbjct: 30 KIIISYITLSSALRADGLNNLTDIGASLAILIGLKISRKPRDPDHPYGHSRAEQIASLVA 89 Query: 182 GVGIFCVGSGLSFYHGVTGILDP-QPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAR 240 + VG + + L+P Q + A+ L AVV V L + AR Sbjct: 90 SFIMATVGLEV-VISAIQSFLNPKQAAPNVLAAWVALFSAVV----MYCVYLYTKKIAAR 144 Query: 241 EANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGT 300 + SL E + + L D G +V + SQ+ P+ D + +++VG Sbjct: 145 TKSKSL-EAAAKDN--------LSDALVSIGTVVG---IVGSQFQ-MPILDPIAALIVGL 191 Query: 301 ILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGS-NLIRYK 359 I+ A + I ++ I ++++E +E + I D+K G+ + Sbjct: 192 IICKTA-WEIFVEASHMLTDGIDPDKMEEYADAIEHIGGVENIVDIKARMYGNQTYVDIT 250 Query: 360 AEVD 363 EVD Sbjct: 251 IEVD 254 >UniRef50_A0LCE7 Cluster: Cation diffusion facilitator family transporter; n=1; Magnetococcus sp. MC-1|Rep: Cation diffusion facilitator family transporter - Magnetococcus sp. (strain MC-1) Length = 401 Score = 43.6 bits (98), Expect = 0.010 Identities = 68/301 (22%), Positives = 124/301 (41%), Gaps = 28/301 (9%) Query: 103 RSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMA 162 ++ R ++ + +N + K+ A S ++ ++ IHS +D ++ + G+ + Q Sbjct: 16 QANRCLIVGVWVNLLLTIAKIIAGVVGNSAAMVADGIHSASDLISDGAVWLGMRVARQEP 75 Query: 163 DPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFV-LGGAV 221 D +HPYG+ +++L + + V G+ V +D W V V Sbjct: 76 DEEHPYGHGRFETLATLFIALALAGVAIGI-----VADAVD-----RIQWGGNVGTPLPV 125 Query: 222 VSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDT---AAVAGVIVAASC 278 ++ A + V +S K A L+ Y R + L+ + + A VAA Sbjct: 126 PTDVALIAVVVSIFTKEA------LFHYTKRVGERLNQRALVANAWHHRSDAVSSVAAMV 179 Query: 279 MAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRS--IPHEQLDEINSVLER 336 + G P+ D + +++V IL VA +L S + + +IN V+E Sbjct: 180 GIVGAQLGWPVMDPIAAVVVAAILFKVAYGFLLEVYREFTDASSAVDEKIQSQINQVIEN 239 Query: 337 DFMIRAIHDVKGIDIGSNLIRYKAEVDFDGRALTRSYLEKHDL--NALLEDMKKIDTIDD 394 +R+ H VK GS+ ++ V G T S E H + L +K+I + D Sbjct: 240 HPDVRSAHLVKARRSGSD-VQVDIHVVVKG---TLSVSEGHQIAEQIRLHLLKEIMAVKD 295 Query: 395 V 395 V Sbjct: 296 V 296 >UniRef50_Q5KK51 Cluster: Di-, tri-valent inorganic cation transporter, putative; n=3; Basidiomycota|Rep: Di-, tri-valent inorganic cation transporter, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 523 Score = 43.6 bits (98), Expect = 0.010 Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 3/93 (3%) Query: 102 TRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQM 161 +R R++ T + I+ FL +L + GS +L ++ H L D ++ ++ Y I + Sbjct: 4 SRQARII-TLLVIDSVFFLIELITGYAVGSLALVADSFHMLNDVLSLIVALYTIRLATSP 62 Query: 162 ADPDHPYGYTNMRYVSSLISGVGI--FCVGSGL 192 + + YG+ + +LI+GV + CV GL Sbjct: 63 SSSANSYGWQRAEILGALINGVFLVALCVSIGL 95 >UniRef50_Q8TT22 Cluster: Cation efflux system protein; n=5; cellular organisms|Rep: Cation efflux system protein - Methanosarcina acetivorans Length = 331 Score = 43.6 bits (98), Expect = 0.010 Identities = 58/269 (21%), Positives = 113/269 (42%), Gaps = 16/269 (5%) Query: 121 FKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLI 180 FK A S ++ ++ +HS +D + + + G+ + + D H YG+ + +S+ Sbjct: 43 FKFFAGIVGNSSAMIADAVHSTSDFMTDIAVIAGLKVAKKPGDSTHNYGHGKIETLSAAF 102 Query: 181 SGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAR 240 G+ + V G+ F+ G+ +L FY + + V+ A V AI++ Sbjct: 103 IGLVLIAVAFGI-FWSGLQKVL------AFYQGETLPAPSRVALAAA--VISIAIKEWLY 153 Query: 241 EANMSLYEYVMRSSDPSVNV-VLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVG 299 M Y +RS + N D + G +V AI + D + ++++ Sbjct: 154 HYTMR-YALKLRSDALTANAWHHRSDAFSSIGTMVGIG-GAILLGGRWVVLDPIAAVILS 211 Query: 300 TILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYK 359 + VA I N+ L+ S+ E I +L + H++K IG N + Sbjct: 212 CFIFKVAFEISYKNLNELLEASLDSETYRSIEEILMSTEGVLGFHELKTRKIG-NAMAAD 270 Query: 360 AEVDFDGRALTRSYLEKHDLNALLEDMKK 388 ++ D R L + ++ H+++ +ED K Sbjct: 271 VHIEVD-RNL--NIVDAHEISTQVEDRLK 296 >UniRef50_Q98H85 Cluster: Cation efflux system protein; n=8; Alphaproteobacteria|Rep: Cation efflux system protein - Rhizobium loti (Mesorhizobium loti) Length = 365 Score = 43.2 bits (97), Expect = 0.014 Identities = 56/239 (23%), Positives = 106/239 (44%), Gaps = 22/239 (9%) Query: 128 YTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFC 187 +TGS +L ++ H LAD + + Y H + + A YG+ ++ + + +G+ IF Sbjct: 87 FTGSLALLADAGHMLADAIALGLAWYAFHLAGRPATGQLTYGFGRVKTLVAYTNGIAIFV 146 Query: 188 VGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLY 247 + + Y +L P P+ + G +V+ G+ L+ + G RE ++++ Sbjct: 147 IALWI-VYEAWQRLLTPAPVLGGPMLVVAILGLLVNIGSFLV-----LHGGDRE-SLNMR 199 Query: 248 EYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVAS 307 ++ +L D A IVAA + ++ +T P+ D + S+LV ++ A Sbjct: 200 GAILH---------VLGDLLGSAAAIVAAVVILVTGWT--PI-DPILSVLVSLLILSTAW 247 Query: 308 FIILSNVGALVGRSIPHEQLDEINSVLERDFM-IRAIH--DVKGIDIGSNLIRYKAEVD 363 ++ + L+ P D I + LE +R +H V ID SN+ A +D Sbjct: 248 SLMRAAAHVLLEGVPPSLDRDLIATDLETTIQGVREVHHMHVWSIDGSSNMATLHACLD 306 >UniRef50_A6BIC1 Cluster: Putative uncharacterized protein; n=1; Dorea longicatena DSM 13814|Rep: Putative uncharacterized protein - Dorea longicatena DSM 13814 Length = 369 Score = 43.2 bits (97), Expect = 0.014 Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 3/131 (2%) Query: 95 VEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYG 154 ++E + R R L I +N K+ S ++ SE I++ D + + G Sbjct: 1 MKESSRQERIIRTSLIGILVNLLIAAVKIVIGTLASSIAIVSEGINNATDAGSSFLTYVG 60 Query: 155 IHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFY-HGVTGILDPQPLHDFYWA 213 S + D HP+GY + Y++ ++ VGI + +G+S + GIL P + Sbjct: 61 TKLSGKHPDEKHPFGYGRIEYLTGMV--VGILILYAGISMLKESIDGILHPSDMKVSMLM 118 Query: 214 YFVLGGAVVSE 224 ++ G V++ Sbjct: 119 VLIVAGTAVTK 129 >UniRef50_Q8TT88 Cluster: Cation efflux system protein; n=4; Methanosarcinaceae|Rep: Cation efflux system protein - Methanosarcina acetivorans Length = 311 Score = 43.2 bits (97), Expect = 0.014 Identities = 23/84 (27%), Positives = 44/84 (52%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 +V++ + +N K+ +TG+ S+ ++ HSL D V+ ++ GI+ S + D D Sbjct: 25 QVLVLVLFLNLAVAFAKIIYGTFTGTLSMTADGYHSLFDGVSNIVGLVGIYISSRPPDRD 84 Query: 166 HPYGYTNMRYVSSLISGVGIFCVG 189 HPYG+ +S+ + + VG Sbjct: 85 HPYGHQKYETFASIFIAILLLFVG 108 >UniRef50_Q97PQ1 Cluster: Cation efflux family protein; n=41; Streptococcus|Rep: Cation efflux family protein - Streptococcus pneumoniae Length = 394 Score = 42.7 bits (96), Expect = 0.018 Identities = 22/68 (32%), Positives = 39/68 (57%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 KL A S SL ++ ++++D + + L GI + Q AD DH +G+ + ++SLI+ Sbjct: 29 KLAAGHLLHSSSLVADGFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLIT 88 Query: 182 GVGIFCVG 189 + +F VG Sbjct: 89 SIIMFYVG 96 >UniRef50_Q7UMH1 Cluster: Cation efflux system protein; n=1; Pirellula sp.|Rep: Cation efflux system protein - Rhodopirellula baltica Length = 331 Score = 42.7 bits (96), Expect = 0.018 Identities = 40/163 (24%), Positives = 74/163 (45%), Gaps = 8/163 (4%) Query: 108 VLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQM-ADPDH 166 +L ++ +N + ++ A +GS +L S+ H+ +D N L++AY + + A+ + Sbjct: 41 LLWSVLLNQALTVAQVIAGILSGSVALLSDAAHNFSD-ANSLLIAYIARRIARKEANQRY 99 Query: 167 PYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGA 226 +GY + + I+ + VG L Y V DPQP+ + A VV G Sbjct: 100 TFGYRRAELIGATINLTLLAVVGCYL-VYEAVHRFFDPQPIIGWLMAVTAAVALVVDLGT 158 Query: 227 TLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAV 269 + L A+ KG+ + ++ D + +V +L AAV Sbjct: 159 AFL--LWAMSKGSLNVRAA---FIHNLVDAAGSVAVLIGAAAV 196 >UniRef50_Q74FW5 Cluster: Cation efflux family protein; n=7; Desulfuromonadales|Rep: Cation efflux family protein - Geobacter sulfurreducens Length = 331 Score = 42.7 bits (96), Expect = 0.018 Identities = 53/254 (20%), Positives = 109/254 (42%), Gaps = 21/254 (8%) Query: 111 AIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGY 170 AI + + ++ +T S +L S+ H D ++ I + A +G+ Sbjct: 18 AIALTALTLVAEIVGGIWTNSLALLSDAAHVFLDLFALVLSLAAIKLASYPASDTKTFGW 77 Query: 171 TNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMV 230 +S I+G +F + G+ FY V +++P+ + G V++ ++ Sbjct: 78 HRAEVFASFINGATVFLMALGI-FYEAVGRLMNPEAVKSLPMLLIATLGLVMN-----LI 131 Query: 231 ALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLP 290 + +A+ + + + +RS+ ++VV D AA GVIV I +TG + Sbjct: 132 SATALHGHSHD------DLNVRSA--FLHVV--GDAAASVGVIVGG---LIMYFTGWYVL 178 Query: 291 DALGSILVGTILGGVASFIILSNVGALVGRSIPH-EQLDEINSVLERDFMIRAIHDVKGI 349 DAL SI +G ++ S+ +L ++ +P ++ + + + A+H + Sbjct: 179 DALISIGIGCVI-FAGSWRVLREAAHILLEGVPRGMSTQQVANEMAGVEGVNAVHQMNIW 237 Query: 350 DIGSNLIRYKAEVD 363 I S+++ A VD Sbjct: 238 TICSHILALSAHVD 251 >UniRef50_A6LME7 Cluster: Cation diffusion facilitator family transporter; n=1; Thermosipho melanesiensis BI429|Rep: Cation diffusion facilitator family transporter - Thermosipho melanesiensis BI429 Length = 294 Score = 42.7 bits (96), Expect = 0.018 Identities = 54/241 (22%), Positives = 105/241 (43%), Gaps = 23/241 (9%) Query: 129 TGSHSLFSECIHSLADTVNQLILAYGIHK-SVQMADPDHPYGYTNMRYVSSLISGVGIFC 187 +GS +L S+ +H+L+DT L+++Y K S + D + YGY V+S+I+ + Sbjct: 36 SGSLALISDALHNLSDT-GALLISYFARKISKKPVDNKYTYGYKRAELVASVINITVLLS 94 Query: 188 VGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLY 247 + L G+ IL P ++ +L A V L+ A+ + + N++L Sbjct: 95 ISFSL-ILEGIKKILSPVQIN----TSIMLIVAYVGLVGNLLTAI--LLSSHSKENLNL- 146 Query: 248 EYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVAS 307 S + +L D + G+I+ M S Y L + ++ G I+ + S Sbjct: 147 --------KSAFLHILSDMFSSVGIIITGHVM--SYYNIWILDPIITFVISGYII--IES 194 Query: 308 FIILSNVGALVGRSIPH-EQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDG 366 IL +V + IP LD++ +++ ++ +H + + + + V DG Sbjct: 195 IKILKESIRVVMQGIPKGVDLDKVKKIIQNFSFVKDVHHIHVWSLDGIELYLEMHVTVDG 254 Query: 367 R 367 + Sbjct: 255 K 255 >UniRef50_A0LLF0 Cluster: Cation diffusion facilitator family transporter precursor; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Cation diffusion facilitator family transporter precursor - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 310 Score = 42.7 bits (96), Expect = 0.018 Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 1/105 (0%) Query: 103 RSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMA 162 + R + ++ N K+ Y GS S+ SE IHS D + I + S + Sbjct: 7 KKSRAAMISVLSNATLVALKIVVGVYIGSVSVISEAIHSGVDLLAAAIAYLAVRTSGRPP 66 Query: 163 DPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPL 207 D HP+G+ +S + + IF + + V + P+P+ Sbjct: 67 DRKHPFGHGKFENISGTVEALLIFLAAAWI-VRESVQKLRHPEPI 110 >UniRef50_A7I5F3 Cluster: Cation diffusion facilitator family transporter; n=1; Candidatus Methanoregula boonei 6A8|Rep: Cation diffusion facilitator family transporter - Methanoregula boonei (strain 6A8) Length = 328 Score = 42.7 bits (96), Expect = 0.018 Identities = 23/76 (30%), Positives = 35/76 (46%) Query: 111 AIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGY 170 ++ N + K F GS S+ SE IHS D + +I + + KS + D H +G+ Sbjct: 22 SVASNTILVILKFAVGFGIGSVSIISEAIHSSMDLIAAVIAFFSVKKSAEPPDHVHEFGH 81 Query: 171 TNMRYVSSLISGVGIF 186 S LI + IF Sbjct: 82 GKFEDASGLIEALLIF 97 >UniRef50_Q67QQ7 Cluster: Cation efflux system protein; n=1; Symbiobacterium thermophilum|Rep: Cation efflux system protein - Symbiobacterium thermophilum Length = 329 Score = 42.3 bits (95), Expect = 0.024 Identities = 61/262 (23%), Positives = 108/262 (41%), Gaps = 25/262 (9%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R L I +N C + + A F GS ++ ++ +S D + L++ G + + D + Sbjct: 16 RAGLLTIAVNLCLTVARAAAGFLAGSTAVLADAANSGTDILATLVVMGGSRIAARPPDWN 75 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 HPYG+ V++ + VGI +GL+ G L GG V Sbjct: 76 HPYGHDKAEPVAAKL--VGILVTFAGLATAAGAVQALR-------------AGGEPVGLA 120 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTA-AVAGVIVAASCM--AIS 282 A ++ A+S A+EA L Y+ R + +L D A V+ +A+ + A+ Sbjct: 121 AAVVTAVSI---AAKEA---LARYLARLGRRLRSQAVLADAANQRTDVLASATALAGALG 174 Query: 283 QYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRA 342 G P+ D L +LV ++ + + V L+ R+ E +D + +R Sbjct: 175 GRFGLPILDPLMGLLVSALILRMGLGLYWQAVRDLMDRAPEPETVDAMRRAALSVPGVRE 234 Query: 343 IHDVKGIDIGSNL-IRYKAEVD 363 + D++ G + K VD Sbjct: 235 VGDLRARVFGPGIYAECKVSVD 256 >UniRef50_A1VD81 Cluster: Cation diffusion facilitator family transporter; n=3; Bacteria|Rep: Cation diffusion facilitator family transporter - Desulfovibrio vulgaris subsp. vulgaris (strain DP4) Length = 481 Score = 42.3 bits (95), Expect = 0.024 Identities = 20/59 (33%), Positives = 32/59 (54%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLI 180 KL F T S + SE HS D V ++ + + + + AD DHPYG+ + +S+L+ Sbjct: 33 KLGVGFATNSLGILSEAAHSGLDLVAAVVTYWAVRAASRPADADHPYGHGKVENLSALV 91 >UniRef50_Q03218 Cluster: Mitochondrial metal transporter 1, mitochondrial precursor; n=3; Saccharomycetales|Rep: Mitochondrial metal transporter 1, mitochondrial precursor - Saccharomyces cerevisiae (Baker's yeast) Length = 510 Score = 42.3 bits (95), Expect = 0.024 Identities = 21/79 (26%), Positives = 37/79 (46%) Query: 101 KTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQ 160 K R+ +G+N + K S +LF++ IH+++D V+ L+ + + Sbjct: 157 KNAGVRITWVGLGVNVGIAIGKFFGGIVFHSQALFADAIHAISDMVSDLLTLLSVGLAAN 216 Query: 161 MADPDHPYGYTNMRYVSSL 179 D+PYGY + V SL Sbjct: 217 KPTADYPYGYGKIETVGSL 235 >UniRef50_A7CNS8 Cluster: Cation diffusion facilitator family transporter; n=1; Opitutaceae bacterium TAV2|Rep: Cation diffusion facilitator family transporter - Opitutaceae bacterium TAV2 Length = 294 Score = 41.9 bits (94), Expect = 0.032 Identities = 17/64 (26%), Positives = 35/64 (54%) Query: 131 SHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGS 190 S++L ++ I S+ D V +++ + S + D DHPYG+ + +L S + + G+ Sbjct: 19 SYALIADGIESINDIVASVVVLISLKVSSKPPDEDHPYGHGKAEQLGALFSAISLLAAGA 78 Query: 191 GLSF 194 ++F Sbjct: 79 TIAF 82 >UniRef50_A7BVM0 Cluster: Cation efflux protein; n=3; Beggiatoa sp. PS|Rep: Cation efflux protein - Beggiatoa sp. PS Length = 451 Score = 41.9 bits (94), Expect = 0.032 Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 1/88 (1%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 +FK+ S +L ++ HSL+ ++ ++ S + D HPYGY ++++ Sbjct: 71 IFKIVFGIIGQSQALIADGFHSLSSLISDFVVLIAAQFSTKPPDVRHPYGYARYETLATI 130 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPL 207 G+ + GL TG+L P+ L Sbjct: 131 TIGILLLITAVGL-LIKAQTGLLAPELL 157 >UniRef50_A4BEK1 Cluster: Predicted Co/Zn/Cd cation transporter; n=1; Reinekea sp. MED297|Rep: Predicted Co/Zn/Cd cation transporter - Reinekea sp. MED297 Length = 387 Score = 41.9 bits (94), Expect = 0.032 Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 14/158 (8%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 + KL F S L ++ HSL+D ++ + + Q D DHPYG+ V + Sbjct: 30 ILKLGVGFAIRSPGLIADGFHSLSDLATDILALLLGNVASQGPDQDHPYGHARYETVGTA 89 Query: 180 ISGVGIFCVGSGLSFYHGVTGILD---PQPLHDFYWAYFVLGGAVVSEGATLMVALSAIR 236 + G + V G++ + +L P P +W + AV+ A+ Sbjct: 90 VLGTVLILVAGGIAI-ESIQALLSGHFPVP----HWTAVI---AVLISIASKEALFQYTH 141 Query: 237 KGAREANMSLYE---YVMRSSDPSVNVVLLEDTAAVAG 271 + A+E N +L E + RS S VVL+ A AG Sbjct: 142 RKAKETNSALLEANAWHSRSDSLSSIVVLVGLIAGFAG 179 >UniRef50_Q97NZ2 Cluster: Cation efflux system protein; n=27; Streptococcus|Rep: Cation efflux system protein - Streptococcus pneumoniae Length = 299 Score = 41.5 bits (93), Expect = 0.042 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 1/80 (1%) Query: 130 GSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVG 189 GS ++ ++ +H L D + I A+ S + D + GY + +L++ V I G Sbjct: 32 GSSAVLADSVHDLGDAIAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAV-ILVTG 90 Query: 190 SGLSFYHGVTGILDPQPLHD 209 S L VT IL PQP++D Sbjct: 91 SVLVILENVTKILHPQPVND 110 >UniRef50_A0Y777 Cluster: Putative transport protein; n=3; Alteromonadales|Rep: Putative transport protein - Alteromonadales bacterium TW-7 Length = 305 Score = 41.5 bits (93), Expect = 0.042 Identities = 58/264 (21%), Positives = 107/264 (40%), Gaps = 21/264 (7%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K AW +GS S+ SL D + + +++ AD DH +G+ ++ L Sbjct: 28 KAWAWLASGSASMLGSLTDSLMDITATFMSFLVLGYALRPADDDHRFGHGKAEALAGL-- 85 Query: 182 GVGIFCVGSG-LSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAR 240 G F GSG L +HGV + +P L +V A+ + V I+ Sbjct: 86 GQAAFIAGSGCLLAFHGVERLFNPIELTHSLLGVWVSAFAIACTLVIVFVQTKVIKH--- 142 Query: 241 EANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGT 300 E + +D +V D A V++A +A+S Y G D + +I V Sbjct: 143 ------TESIAIKAD---SVHYKGDLILNAAVLIA---IALSYY-GMMYADPIFAIGVAG 189 Query: 301 ILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGS-NLIRYK 359 L + I + L+ + +P ++ I + + + +H ++ G I+ Sbjct: 190 YLLYNSWDIARDSADHLMDKELPDDEKQSIFDIAKEHSDVHGVHGIRTRQGGKIKFIQMH 249 Query: 360 AEVDFDGRALTRSYLEKHDLNALL 383 E+D D +L R++ ++ A++ Sbjct: 250 LELD-DHLSLIRAHTVADEVEAMI 272 >UniRef50_A0L9V8 Cluster: Cation diffusion facilitator family transporter; n=1; Magnetococcus sp. MC-1|Rep: Cation diffusion facilitator family transporter - Magnetococcus sp. (strain MC-1) Length = 294 Score = 41.5 bits (93), Expect = 0.042 Identities = 46/228 (20%), Positives = 98/228 (42%), Gaps = 19/228 (8%) Query: 129 TGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCV 188 +G +L ++ HS AD + + + S + AD DH YG+ ++++SS I G+ I Sbjct: 35 SGCQALVADAFHSSADVMASTVTLASLKISERPADDDHHYGHGKVQFISSSIVGL-ILIT 93 Query: 189 GSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVAL-SAIRKGAREANMSLY 247 G+ + I+ +D +LG A+ LM S + K Sbjct: 94 GAIFILIDAIKTIVTGD--YDAPNRIAILGAAISVISNELMFRYQSCVGK---------- 141 Query: 248 EYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVAS 307 +++ P++ ++ + I +A + + G P+ D L ++ V ++ + Sbjct: 142 ----QNNSPAIMANAWDNRSDAFSSIAVMIGVAFATF-GFPVADPLAALGVSVLVIRIGI 196 Query: 308 FIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNL 355 + L + L+ S E+L++I +++ + I+ ++ +G NL Sbjct: 197 ELNLEAIDGLMDASPEMEELEDIYKIVKDVSSVHGINYMRARTMGDNL 244 >UniRef50_Q8ZYX3 Cluster: Cation efflux system protein, conjectural; n=4; Pyrobaculum|Rep: Cation efflux system protein, conjectural - Pyrobaculum aerophilum Length = 319 Score = 41.5 bits (93), Expect = 0.042 Identities = 33/152 (21%), Positives = 69/152 (45%), Gaps = 4/152 (2%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 L K+ AW + S ++ ++ +HS D + I + S++ D +HPYG+ + + Sbjct: 19 LLKIVAWSQSFSVAVLADAVHSAVDLLAVTITYLAVKASLKPPDREHPYGHHKAETLGGI 78 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 + + G+ +S Y V ++ +P ++ A+V + ++V L R + Sbjct: 79 GGSLAVMASGAFIS-YEAVMKLIHWEPFAPTALGIAIVALAIVIDFNRVLV-LRRFRGVS 136 Query: 240 R--EANMSLYEYVMRSSDPSVNVVLLEDTAAV 269 R EA+ + + SS + V++ +AV Sbjct: 137 RALEADALHFSTDLASSSAILAVLIFGAFSAV 168 >UniRef50_Q97MV4 Cluster: Predicted Co/Zn/Cd cation transporter; n=1; Clostridium acetobutylicum|Rep: Predicted Co/Zn/Cd cation transporter - Clostridium acetobutylicum Length = 292 Score = 41.1 bits (92), Expect = 0.056 Identities = 26/107 (24%), Positives = 54/107 (50%), Gaps = 4/107 (3%) Query: 92 KDNVEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLIL 151 +DN + + + R R+ L + +FK ++ S +L ++ I+S D + + + Sbjct: 2 EDNYKNLKIAERGVRISLIIYVVLS---IFKFFMGYFFKSEALKADGINSSTDIIAAIAI 58 Query: 152 AYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGV 198 G+ + + AD +H YG+ +SSL++ + + VG + Y+GV Sbjct: 59 IVGLKIARKPADKEHTYGHLRAETISSLLASLIMIAVGVDV-VYNGV 104 >UniRef50_A1IAH4 Cluster: Cation diffusion facilitator family transporter; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Cation diffusion facilitator family transporter - Candidatus Desulfococcus oleovorans Hxd3 Length = 320 Score = 41.1 bits (92), Expect = 0.056 Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 4/88 (4%) Query: 112 IGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYT 171 IG+ G F+ F S ++ ++ +HSL+D + + G+ D HPYG+ Sbjct: 47 IGLAGLKFV----VGFLGASQAVIADAVHSLSDMTTDIAVLVGVKFWSAPPDTCHPYGHK 102 Query: 172 NMRYVSSLISGVGIFCVGSGLSFYHGVT 199 + + ++ G+ + V GL++ VT Sbjct: 103 RVEALVTIFIGITLAAVACGLAYRAMVT 130 >UniRef50_Q8F433 Cluster: Cobalt-zinc-cadmium resistance protein czcD; n=4; Leptospira|Rep: Cobalt-zinc-cadmium resistance protein czcD - Leptospira interrogans Length = 317 Score = 40.7 bits (91), Expect = 0.074 Identities = 47/204 (23%), Positives = 89/204 (43%), Gaps = 21/204 (10%) Query: 96 EEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGI 155 +E GLK R +L AI ++ F +L F +GS +L ++ H + DT+ + + Sbjct: 15 QEKGLK----RSILLAILVSISIFFVELFGGFQSGSIALLADAGHIITDTIALSLSLIAV 70 Query: 156 HKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYF 215 S + + +GY + ++SL++ + IF + S FY + + + + F ++ Sbjct: 71 LLSSKKPNYRFSFGYYRIEILTSLLNSILIFGI-SFYIFYESIERFQNQKEILSFQMIFY 129 Query: 216 VLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVA 275 G + + L+ A R N+ S V +L D + GV+V Sbjct: 130 SSFGIIFN----LISAWILFRFSGENINIK-----------SAYVHVLSDLLSTVGVLVG 174 Query: 276 ASCMAISQYTG-NPLPDALGSILV 298 + + I+ + +PL L SIL+ Sbjct: 175 SILIYITNWNWIDPLISVLISILI 198 >UniRef50_A5IIQ7 Cluster: Cation diffusion facilitator family transporter; n=2; Thermotoga|Rep: Cation diffusion facilitator family transporter - Thermotoga petrophila RKU-1 Length = 306 Score = 40.7 bits (91), Expect = 0.074 Identities = 62/290 (21%), Positives = 123/290 (42%), Gaps = 25/290 (8%) Query: 112 IGINGCNFL--FKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYG 169 IGI G L K+ TGS+++ ++ I + D ++ S + D HPYG Sbjct: 13 IGILGNTVLAVLKILVGLLTGSYAILADGIDTSTDIFTSFVILLSSRISGKPPDETHPYG 72 Query: 170 YTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLM 229 + ++S I +F G+ L V ++ + + F++ G V+ G T + Sbjct: 73 HERAETIASKIISFVMFYAGASL-LVESVKRLVKQEFSLELTLTAFIVVGISVA-GKTFL 130 Query: 230 VALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPL 289 L + G R ++SS + + + + ++G ++A M + G Sbjct: 131 F-LYKLSLGKR----------LKSSATISDALNMRNDIMISGTVLAG--MVAMKTFGWWW 177 Query: 290 PDALGSILVGTILGGVASFIILSNVGALVG--RSIPHEQLDEINSVLERDFMIRAIHDVK 347 D+L +I V ++ + + L+ + + D+I +VLER + H V+ Sbjct: 178 LDSLLAIFVSIMILRTSFSVFYEAAYELMDGMKRTELDMYDDIFAVLERFPNVHNPHRVR 237 Query: 348 GIDIGSNLIRYKAEVDFDGRALTRSYLEKHDLNALL--EDMKKIDTIDDV 395 +G+ + +++ DG+ S + H+L + E +K+ D I+DV Sbjct: 238 IRKVGTRHF-IEMDIEVDGK---MSVKDAHELTVKIRKEMLKRRDDIEDV 283 >UniRef50_A0Q5V4 Cluster: Predicted Co/Zn/Cd cation transporter; n=11; Francisella tularensis|Rep: Predicted Co/Zn/Cd cation transporter - Francisella tularensis subsp. novicida (strain U112) Length = 379 Score = 40.7 bits (91), Expect = 0.074 Identities = 22/97 (22%), Positives = 48/97 (49%), Gaps = 1/97 (1%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 +V L + IN + K S +LF++ IHS +D ++ ++ + + + D + Sbjct: 11 KVTLVGMFINALLAISKTLIGVIGRSPALFADGIHSFSDLLSDFMVLFAAKYANKGEDHN 70 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGIL 202 HPYG+ + +++L+ + +G + YH + +L Sbjct: 71 HPYGHERLETLATLVLSGLLITIGF-MIVYHSLVSLL 106 >UniRef50_A7SP61 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 185 Score = 40.7 bits (91), Expect = 0.074 Identities = 18/49 (36%), Positives = 31/49 (63%), Gaps = 1/49 (2%) Query: 3 AMTEYLLKQSDLESLPKVLRRSPY-ESEPPITVYYRRDVEAKAIEIWGS 50 A +YLL DL+ L + +P +S PP+ ++ +V++KA+E+WGS Sbjct: 18 AKRDYLLSDEDLKELNHETKDNPINKSYPPMKIFKLSEVKSKAVEVWGS 66 >UniRef50_Q9PF12 Cluster: Cobalt-zinc-cadmium resistance protein; n=26; Proteobacteria|Rep: Cobalt-zinc-cadmium resistance protein - Xylella fastidiosa Length = 321 Score = 40.3 bits (90), Expect = 0.097 Identities = 24/97 (24%), Positives = 43/97 (44%), Gaps = 1/97 (1%) Query: 111 AIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGY 170 A+G+ + ++ T S +L S+ +H D +I + S + D YGY Sbjct: 42 ALGLTASFLVAEIIGAVLTRSLALLSDAVHMATDVFALMIALVAVRLSRRPPDVRRTYGY 101 Query: 171 TNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPL 207 + +L++GV +F VG G + V + PQ + Sbjct: 102 ARLEAFGALVNGVLLFGVG-GYILWEAVQRLRAPQEI 137 >UniRef50_Q6AS02 Cluster: Conserved hypothetical membrane protein; n=1; Desulfotalea psychrophila|Rep: Conserved hypothetical membrane protein - Desulfotalea psychrophila Length = 345 Score = 40.3 bits (90), Expect = 0.097 Identities = 28/127 (22%), Positives = 56/127 (44%), Gaps = 4/127 (3%) Query: 96 EEVGLKTRSGRVVLTAIGINGCNFLF--KLCAWFYTGSHSLFSECIHSLADTVNQLILAY 153 E++G ++ RV + + F+ K A+ + S ++FS+ S + V L+ Sbjct: 13 EKIGQDSKD-RVKAARVSLVASFFIMCCKFAAFIVSDSQAIFSDAAESTVNVVAALLALI 71 Query: 154 GIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWA 213 I +++ AD HPYG+ M + S+ G G+ + V + Q + + + Sbjct: 72 IITMAMKPADDRHPYGHGKMEFFSAAFEG-GLITFAALAILVKAVNALFYGQEIKELGYG 130 Query: 214 YFVLGGA 220 ++G A Sbjct: 131 LLLIGFA 137 >UniRef50_A3ERL9 Cluster: Putative Co/Zn/Cd cation transporter; n=1; Leptospirillum sp. Group II UBA|Rep: Putative Co/Zn/Cd cation transporter - Leptospirillum sp. Group II UBA Length = 302 Score = 40.3 bits (90), Expect = 0.097 Identities = 25/91 (27%), Positives = 48/91 (52%), Gaps = 3/91 (3%) Query: 100 LKTRSGRVVLTAIGINGCNFLFKLCAWFYT-GSHSLFSECIHSLADTVNQLILAYGIHKS 158 L+T +G + L A+ IN + K+ W ++ S + ++ H+L D+V+ LI G+ + Sbjct: 8 LRTPAGTLTL-ALTINTFLSILKI-GWGHSIHSAGMIADGYHALLDSVSDLICLVGVSMA 65 Query: 159 VQMADPDHPYGYTNMRYVSSLISGVGIFCVG 189 + D +HPYG+ ++ + V +F G Sbjct: 66 NRPPDENHPYGHGKFEPLAQVAVSVFLFLTG 96 >UniRef50_A0L9W4 Cluster: Cation diffusion facilitator family transporter; n=1; Magnetococcus sp. MC-1|Rep: Cation diffusion facilitator family transporter - Magnetococcus sp. (strain MC-1) Length = 332 Score = 40.3 bits (90), Expect = 0.097 Identities = 15/59 (25%), Positives = 33/59 (55%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLI 180 K+ +GSH+L ++ ++S D + ++ G+ S + D HP+G+ + ++ SL+ Sbjct: 28 KIFVGIISGSHALLADALYSSKDVITSALIIVGLKVSNKPIDEKHPFGHGKIEFLLSLV 86 >UniRef50_A6UWS0 Cluster: Cation diffusion facilitator family transporter; n=1; Methanococcus aeolicus Nankai-3|Rep: Cation diffusion facilitator family transporter - Methanococcus aeolicus Nankai-3 Length = 422 Score = 40.3 bits (90), Expect = 0.097 Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 4/101 (3%) Query: 127 FYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIF 186 + +GS +L ++ +HSL+D + + + G+ S + + PYGY+ ++SL IF Sbjct: 30 YISGSVALIADALHSLSDVLGPIAVYVGLKISQKKPNMKFPYGYSRAETLASLFVSFIIF 89 Query: 187 CVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGAT 227 G + + +P P+ Y A ++ ++S G T Sbjct: 90 LTGVE-TLRQSIDKFFNPSPI-SHYGAVIIV--VLISIGIT 126 >UniRef50_Q8L725 Cluster: Metal tolerance protein C1; n=2; Arabidopsis thaliana|Rep: Metal tolerance protein C1 - Arabidopsis thaliana (Mouse-ear cress) Length = 471 Score = 40.3 bits (90), Expect = 0.097 Identities = 45/242 (18%), Positives = 104/242 (42%), Gaps = 18/242 (7%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K + GS ++ ++ HS++D V + + D +HPYG+ + +L Sbjct: 91 KALTGYLCGSTAIIADAAHSVSDVVLSGVALVSYRAANVPKDKEHPYGHGKFETLGALGI 150 Query: 182 GVGIFCVGSGLSFYH----GVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRK 237 + GSG++++ + P+ +H + + +++ T+ +A +I++ Sbjct: 151 SAMLLATGSGIAWHALDLLSIALSAAPEVIHSGHHHGIDMNHPILA--LTVTIASISIKE 208 Query: 238 GAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLP----DAL 293 G LY R+ + + +++ + + +S +A+ G+ L D L Sbjct: 209 G-------LYWITKRAGEKQGSGLMMANAWHHRSDAI-SSLVALVGVGGSILGVNFLDPL 260 Query: 294 GSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGS 353 ++V T++ ++ LV +IP +QL+ I + + ++ H ++G GS Sbjct: 261 AGLVVSTMIVNAGLKTGHQSILELVDAAIPAQQLEPIRQTILQVEGVKGCHRLRGRRAGS 320 Query: 354 NL 355 +L Sbjct: 321 SL 322 >UniRef50_Q2PY00 Cluster: Nucleoside transporter; n=1; uncultured marine bacterium Ant4D5|Rep: Nucleoside transporter - uncultured marine bacterium Ant4D5 Length = 435 Score = 39.9 bits (89), Expect = 0.13 Identities = 22/96 (22%), Positives = 49/96 (51%), Gaps = 4/96 (4%) Query: 215 FVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIV 274 +V+ + + GA + A S I G E+ + + Y+ R ++ + ++ A ++G ++ Sbjct: 147 WVMQRTMKTSGAETLCAASNIFVGMMESPLVVKPYIERMTESELMAIMTAGLATISGSVL 206 Query: 275 AASCMAISQYTGNPLPDALGSILVGTILGGVASFII 310 AA +S + PDA G ++ +I+ A+F++ Sbjct: 207 AAYAGMLSPFE----PDAAGHLIAASIMSAPAAFVM 238 >UniRef50_Q036T5 Cluster: Predicted Co/Zn/Cd cation transporter; n=1; Lactobacillus casei ATCC 334|Rep: Predicted Co/Zn/Cd cation transporter - Lactobacillus casei (strain ATCC 334) Length = 349 Score = 39.9 bits (89), Expect = 0.13 Identities = 20/70 (28%), Positives = 40/70 (57%), Gaps = 2/70 (2%) Query: 131 SHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGS 190 S +L ++ +++L + LIL +G+ S Q D +H +G+ + +++L SG+ + VG Sbjct: 48 SRALAADGLNNLTGVASALILLWGLQISQQRPDSEHRFGHWRFQTIATLFSGLIMLVVGL 107 Query: 191 G--LSFYHGV 198 + YHG+ Sbjct: 108 DVVIDGYHGL 117 >UniRef50_A6EF02 Cluster: Cation efflux system protein; n=1; Pedobacter sp. BAL39|Rep: Cation efflux system protein - Pedobacter sp. BAL39 Length = 292 Score = 39.9 bits (89), Expect = 0.13 Identities = 26/99 (26%), Positives = 50/99 (50%), Gaps = 4/99 (4%) Query: 128 YTG-SHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIF 186 Y G S++L ++ S AD ++ +L + + + D HPYG+ V++++ +G+F Sbjct: 30 YLGHSYALIADATESGADVISSGLLWLALLYAQRPPDKGHPYGHGKAEPVAAVV--IGLF 87 Query: 187 CVG-SGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSE 224 +G +G YH + I P L + + +L +V E Sbjct: 88 LLGAAGWIAYHAIGYINTPHALPGKFTLFVLLAVVLVKE 126 >UniRef50_A6CGW2 Cluster: Putative cation efflux system protein; n=1; Planctomyces maris DSM 8797|Rep: Putative cation efflux system protein - Planctomyces maris DSM 8797 Length = 331 Score = 39.9 bits (89), Expect = 0.13 Identities = 23/94 (24%), Positives = 41/94 (43%) Query: 102 TRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQM 161 TR +V I + + +L ++ G L + + S AD + L + + I + Q Sbjct: 41 TRLFKVAWLGISVRLFVIVMELVGLWFLGHSVLLVDALASSADVLTSLAILFAIRLAEQP 100 Query: 162 ADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFY 195 D DHP+G+ ++ G+ I VG+ Y Sbjct: 101 PDDDHPFGHGRYEPLAGFQLGILILIVGAATFGY 134 >UniRef50_A4M6M7 Cluster: Cation diffusion facilitator family transporter; n=1; Petrotoga mobilis SJ95|Rep: Cation diffusion facilitator family transporter - Petrotoga mobilis SJ95 Length = 323 Score = 39.9 bits (89), Expect = 0.13 Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 7/112 (6%) Query: 114 INGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNM 173 ING FKL F TGS ++ ++ I + D + ++ S + AD HP+G+ Sbjct: 30 INGALAFFKLVISFITGSMAILADGIDTTTDIITSILTLIASKISSKPADDSHPFGHERA 89 Query: 174 RYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDF--YWAYFVLGGAVVS 223 + + + + I G + + G + H F Y Y VL +++S Sbjct: 90 ETIVTKVLSLVIIYAG-----FQVLIGAIQSIITHSFSIYRPYLVLWISLIS 136 >UniRef50_A4IN96 Cluster: Cation efflux family protein; n=3; Bacillaceae|Rep: Cation efflux family protein - Geobacillus thermodenitrificans (strain NG80-2) Length = 296 Score = 39.9 bits (89), Expect = 0.13 Identities = 24/95 (25%), Positives = 48/95 (50%) Query: 95 VEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYG 154 V+ V K R+ L +IG+ KL A GS + ++ ++L+D + + + G Sbjct: 2 VKNVEWKQRAEAGALLSIGVYLLLAACKLLAGSLAGSDGVKADGWNNLSDVIASVAVYIG 61 Query: 155 IHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVG 189 + + + D +HPYG++ +SSL++ + +G Sbjct: 62 MKIAQKPRDRNHPYGHSRAENISSLLAAFLMMSIG 96 >UniRef50_A3DKT1 Cluster: Cation diffusion facilitator family transporter; n=1; Staphylothermus marinus F1|Rep: Cation diffusion facilitator family transporter - Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) Length = 284 Score = 39.9 bits (89), Expect = 0.13 Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 8/120 (6%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 L K+ + S SL + + S A+ V + + Y S+ D DHPYG+ + + + Sbjct: 24 LVKIYGAIFYNSRSLLVDALTSFANIVALIFIVYFYKLSISPPDIDHPYGHHRLG-IGGI 82 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 I+ + + +G+S+ V + + Y+A + G ++ L+ L AIR G+ Sbjct: 83 IASIAAYSFVAGVSYTELVYSTVYTVQIQSVYYA---IAGFII----YLITILLAIRIGS 135 >UniRef50_Q607F9 Cluster: Cation efflux family protein; n=7; Bacteria|Rep: Cation efflux family protein - Methylococcus capsulatus Length = 376 Score = 39.5 bits (88), Expect = 0.17 Identities = 54/235 (22%), Positives = 93/235 (39%), Gaps = 19/235 (8%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 K A+ TGS L S+ + S+ + ++ + S Q AD H +G+ Y +S Sbjct: 25 KAAAYRVTGSVGLLSDALESIVNLSAAVVALAMLRLSAQPADARHHFGHGKAEYFASGFE 84 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGARE 241 GV + V +G + L P L + + A V G + +S RK Sbjct: 85 GV-LILVAAGAILFAAWDRYLHPHELAELDLGLGLSVAAAVVNGLVGWLLVSVGRKAGS- 142 Query: 242 ANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTI 301 ++ +D LL D GV+ + + TG D + LVG Sbjct: 143 --------IVLEADGKH---LLTDVWTSIGVVCGVAAAGL---TGWHDFDPGVAALVGLN 188 Query: 302 LGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAI--HDVKGIDIGSN 354 + + +I + L+ S+P E+ +I +LE F R + HD++ G++ Sbjct: 189 IVWTGAGLIRRTIAGLLDASLPLEENLKIRGILE-TFRERGVGFHDLRTRQSGAH 242 >UniRef50_A5WCY6 Cluster: Cation diffusion facilitator family transporter; n=2; Psychrobacter|Rep: Cation diffusion facilitator family transporter - Psychrobacter sp. PRwf-1 Length = 359 Score = 39.5 bits (88), Expect = 0.17 Identities = 43/173 (24%), Positives = 77/173 (44%), Gaps = 11/173 (6%) Query: 261 VLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGR 320 VL + +VA +I A + M + + +P+ + ++L+ ++ G F ++ ++ Sbjct: 193 VLGDLLGSVAAIIAALAMMWMGWWWADPVASVIVAVLI--LMSG---FRVVKASTHILME 247 Query: 321 SIPHE-QLDEINSVLERDFMIRAIHD--VKGIDIGSNLIRYKAEVDFDGRALTRSYLEKH 377 P E LD++ +E + I A+HD V I G + + VD D R L S L H Sbjct: 248 GTPEEISLDDVKHTIEHNEHIIAVHDLHVWSITSGLHALSCHVVVDGDMRILEASEL-IH 306 Query: 378 DLNALLEDMKKIDTIDDVETFLLKHGENIVDMLGGEIDRIELKLRKKFPQIRH 430 +L LE + T VE+ ++H N +D + ++ E I H Sbjct: 307 ELEHSLERLGISHTTIQVES--IEHPHNRLDAITCALEDTETSRHSGHSHIGH 357 >UniRef50_A1ZDC5 Cluster: Heavy metal efflux pump, CzcD family; n=1; Microscilla marina ATCC 23134|Rep: Heavy metal efflux pump, CzcD family - Microscilla marina ATCC 23134 Length = 331 Score = 39.5 bits (88), Expect = 0.17 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 1/98 (1%) Query: 111 AIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGY 170 A +N C + +L T S ++ S+ IH L DT+ + S + D + YGY Sbjct: 54 AFFLNFCFTIIELIGGVLTNSMAIMSDAIHDLGDTIAIGSAWFMERYSEKGCDDRYNYGY 113 Query: 171 TNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLH 208 +S+ I+ V I VGS F + ++ P+ ++ Sbjct: 114 KRFSPLSAFITSV-ILIVGSVFIFIETIPRLIHPEAVN 150 >UniRef50_A3H9P4 Cluster: Cation diffusion facilitator family transporter; n=1; Caldivirga maquilingensis IC-167|Rep: Cation diffusion facilitator family transporter - Caldivirga maquilingensis IC-167 Length = 298 Score = 39.5 bits (88), Expect = 0.17 Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 11/156 (7%) Query: 134 LFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSS-----LISGVGIFCV 188 L ++ +H++ D V L G+ +++ D DHPYG+ RY+S +I G ++ V Sbjct: 53 LIADGLHTMLDVVILGSLYIGLGPTLKPPDMDHPYGHFKYRYLSMYTVAIIIMGASLWLV 112 Query: 189 GSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYE 248 + + G+++ PL Y + G V+S L + + I+ G + Sbjct: 113 AEAIISI--IKGVIERLPLDSLY-VIIAVAGLVLSR--LLYLRIGYIKTGDLILKLEFRH 167 Query: 249 YVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQY 284 + D + L + + +I + MAI+ Y Sbjct: 168 AIADLLDALLIAATLV-VSLIIPIIQPVAVMAIAAY 202 >UniRef50_Q6D7E5 Cluster: Zinc transporter zitB; n=40; Enterobacteriaceae|Rep: Zinc transporter zitB - Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) Length = 320 Score = 39.5 bits (88), Expect = 0.17 Identities = 50/235 (21%), Positives = 99/235 (42%), Gaps = 29/235 (12%) Query: 102 TRSG--RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 T SG + +L A I + ++ +GS +L ++ H L D + + + Sbjct: 8 TESGNSKRLLAAFIITATFMVAEVIGGLLSGSLALLADAGHMLTDAAALFVALVAVRFAQ 67 Query: 160 QMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGG 219 + + H +GY + +++ ++ + + + + F+ + DPQP+ + G Sbjct: 68 RKPNARHTFGYLRLTTLAAFVNALTLILI-TAFIFWEAIQRFYDPQPVAGVPMLLVAIAG 126 Query: 220 AVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCM 279 + + +VA + G+ E N+++ + +L D G I AA + Sbjct: 127 LLAN-----IVAFWLLHHGSEEKNINVRAAALH---------VLGDLLGSVGAIAAAIII 172 Query: 280 AISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVL 334 + +T P+ D + SILV S ++L + AL+ SI HE L+ S L Sbjct: 173 LYTNWT--PI-DPILSILV--------SCLVLRSAWALLKESI-HELLEGTPSQL 215 >UniRef50_Q12263 Cluster: Serine/threonine-protein kinase GIN4; n=4; Eukaryota|Rep: Serine/threonine-protein kinase GIN4 - Saccharomyces cerevisiae (Baker's yeast) Length = 1142 Score = 39.5 bits (88), Expect = 0.17 Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 12/126 (9%) Query: 312 SNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDGRALTR 371 SN L+ +E+ ++I E++ + R + + K + L R + + + RA R Sbjct: 541 SNFATLIDEIFEYEKYEQIRK--EKEELERKVREAKARE---ELERRRRKQEEKERA--R 593 Query: 372 SYLEKHDLNALLEDMKKIDTID--DVETFLLKHGENIVDMLGGEIDRIELKLRKKFPQIR 429 LEK DL E++KK ID D+E L KH E + L G I I + + I Sbjct: 594 KLLEKEDLKRKQEELKKQIEIDISDLEQELSKHKE---EKLDGNIRSISAPMENEEKNIN 650 Query: 430 HCDLEI 435 H +++I Sbjct: 651 HLEVDI 656 >UniRef50_Q2NTU9 Cluster: Putative transport protein; n=1; Sodalis glossinidius str. 'morsitans'|Rep: Putative transport protein - Sodalis glossinidius (strain morsitans) Length = 342 Score = 39.1 bits (87), Expect = 0.22 Identities = 49/273 (17%), Positives = 106/273 (38%), Gaps = 17/273 (6%) Query: 95 VEEVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYG 154 + ++ K+ + L ++G+ K+ AW TGS +L + L D + ++ G Sbjct: 2 IAKLSKKSLTRLASLVSLGVALTLVYIKIWAWIETGSIALLTSAADGLVDVLASMVTLVG 61 Query: 155 IHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAY 214 + + + AD H +G+ +++ + + L ++ + PQPL Sbjct: 62 GYYAQRPADRGHRFGHGKAEAIAAFVQARRLAAAEVALG-VESISRPITPQPL------- 113 Query: 215 FVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIV 274 AV G ++VA + + +Y ++ + + D A V+ Sbjct: 114 -----AVQRLGIIVIVASTLCASLLVTMQTRVVKYTQSTAIAADRAHYITDIAVNIAVLC 168 Query: 275 AASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVL 334 A + + G DA G++ + + A II S + L+ R + I + Sbjct: 169 A---LVLENQFGWVRADASGALAISCYMVWNARGIIQSAMLQLLDRELDSADRRRITAAA 225 Query: 335 ERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDGR 367 + +HD++ + G + + + V+ DG+ Sbjct: 226 LNCPGVEGVHDLRTRN-GGDRVFVELHVEVDGQ 257 >UniRef50_O67851 Cluster: Putative uncharacterized protein; n=1; Aquifex aeolicus|Rep: Putative uncharacterized protein - Aquifex aeolicus Length = 385 Score = 39.1 bits (87), Expect = 0.22 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%) Query: 109 LTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPY 168 L + G N L KL TGS SL + IHSL+D LI I K ++ PY Sbjct: 8 LVSFGFNIFQSLIKLVGGLLTGSLSLIGDAIHSLSDATASLIAFLSI-KFSEIKSERFPY 66 Query: 169 GYTNMRYVSSLI 180 G + + +++ Sbjct: 67 GLYKLENIGAIV 78 >UniRef50_A0VV15 Cluster: Cation diffusion facilitator family transporter; n=6; Alphaproteobacteria|Rep: Cation diffusion facilitator family transporter - Dinoroseobacter shibae DFL 12 Length = 328 Score = 39.1 bits (87), Expect = 0.22 Identities = 37/168 (22%), Positives = 70/168 (41%), Gaps = 2/168 (1%) Query: 104 SGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMAD 163 SG+ ++ + + G F+ +L +TGS ++ S+ H+L+ L+ + + AD Sbjct: 13 SGKALVISAWLTGVYFVIELAVGLWTGSIAVLSDAFHTLSAVGGVLVAITAQRIARRPAD 72 Query: 164 PDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVS 223 +G+ + +L++G G + L + G + DP L + GG V Sbjct: 73 STRSFGWYRAEIIGALVNG-GFLLGMALLVIWMGAMRLGDPIHLATGPMLWVAFGGLVTE 131 Query: 224 -EGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVA 270 LM S AR A + + + S V +++E T +A Sbjct: 132 VVSLALMWQSSKDDLNARGALWHIIQTFVGSLLIIVTALVIEFTGFLA 179 >UniRef50_UPI0000499CA1 Cluster: cation diffusion facilitator family protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep: cation diffusion facilitator family protein - Entamoeba histolytica HM-1:IMSS Length = 437 Score = 38.7 bits (86), Expect = 0.30 Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 3/134 (2%) Query: 114 INGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNM 173 +N C FLF+L Y S L + + L+D ++Q+I Q YG+T Sbjct: 70 MNFCYFLFELIIGLYLNSLILTVDSFNMLSDILSQIIGLTATIIMKQNFSSKFTYGFTRA 129 Query: 174 RYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSE--GATLMVA 231 + I+ V +G +S + + + + D + V GG +V G ++ Sbjct: 130 EVTGAFINSVFQISIGLFMSI-QSIESFFELEEVKDPLFLLAVSGGGLVVNIIGMIILHE 188 Query: 232 LSAIRKGAREANMS 245 S I+K ++ N S Sbjct: 189 YSCIKKVNKKINSS 202 >UniRef50_Q3AYC0 Cluster: Cation efflux protein; n=13; Cyanobacteria|Rep: Cation efflux protein - Synechococcus sp. (strain CC9902) Length = 308 Score = 38.7 bits (86), Expect = 0.30 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 1/82 (1%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 RV+ A+ +N L KL +GS ++ ++ +HS D ++ L S D D Sbjct: 18 RVLAVALVMNIAMSLLKLSVGVLSGSLAVIADAMHSATDALSSLTGLITNSLSDPRPDRD 77 Query: 166 HPYGYTNMRYVSSL-ISGVGIF 186 HPYG+ V +L I+G +F Sbjct: 78 HPYGHHKYEAVGALGIAGFILF 99 >UniRef50_Q2NBG7 Cluster: Cation efflux system protein; n=3; Proteobacteria|Rep: Cation efflux system protein - Erythrobacter litoralis (strain HTCC2594) Length = 317 Score = 38.7 bits (86), Expect = 0.30 Identities = 48/228 (21%), Positives = 98/228 (42%), Gaps = 13/228 (5%) Query: 99 GLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKS 158 G + S R ++ A+ IN L ++ +GS +L ++ +H+ +D + + + Sbjct: 13 GEENLSDRQLILAVAINVLLTLAQIVGGILSGSLALIADALHNFSDAASLGLAWFARRIG 72 Query: 159 VQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLG 218 + AD +GY V++LI+ + +G L + PQP+ + + +V G Sbjct: 73 RRPADKLMTFGYAQGEVVAALINLTTLLIIGFYL-IVEAINRFAAPQPV-EGWTVIWVAG 130 Query: 219 GAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSD--PSVNVV-----LLEDTAAVAG 271 A+V + T + + +GA ++ ++ SD S+ V+ ++ VA Sbjct: 131 IALVIDLVTAFI----VYRGAHDSINMKAAFLHNVSDALASIGVIVAGVLIILYDLVVAD 186 Query: 272 VIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVG 319 +I+ A + G L +L+G + V ++ N+ AL G Sbjct: 187 LIITLIIAAYVIWQGATLLPRTVRLLMGAVPDEVEFDQMVENLRALGG 234 >UniRef50_A5TUV7 Cluster: Possible CDF family cation diffusion facilitator, cadmium (Cd2+), zinc (Zn2+), cobalt (Co2+) efflux permease; n=3; Fusobacterium nucleatum|Rep: Possible CDF family cation diffusion facilitator, cadmium (Cd2+), zinc (Zn2+), cobalt (Co2+) efflux permease - Fusobacterium nucleatum subsp. polymorphum ATCC 10953 Length = 372 Score = 38.7 bits (86), Expect = 0.30 Identities = 44/215 (20%), Positives = 91/215 (42%), Gaps = 17/215 (7%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 +FK + S ++ + +++L+D ++ ++ + D HP G+ + Y+S++ Sbjct: 29 VFKAIIGLISNSIAILLDAVNNLSDALSSIVTIIATKLADSEPDKKHPLGHGRIEYLSAM 88 Query: 180 ISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGA 239 I IF G S + I +P + + +L +VS L++ G Sbjct: 89 IVAGIIFYAGI-TSLIESIKKIFNPLEVEYSKVTFIIL---IVSIVLKLLLGRYVKNIGE 144 Query: 240 REANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVG 299 + + SL V SD + + + L + V+ ++ + + I Y G L SI + Sbjct: 145 KFNSPSL---VASGSDATFDAI-LSSSVLVSAILYIFTDINIEAYVG-----VLISIFI- 194 Query: 300 TILGGVASFIILSNVGALVGRSIPHEQLDEINSVL 334 I G+ I + V ++G + E ++EI + Sbjct: 195 -IKSGIE--IFMEAVNEILGERVDKETINEIKKTI 226 >UniRef50_A1W8N6 Cluster: Putative uncharacterized protein; n=3; Comamonadaceae|Rep: Putative uncharacterized protein - Acidovorax sp. (strain JS42) Length = 125 Score = 38.7 bits (86), Expect = 0.30 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Query: 269 VAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLD 328 VAGV+ AS A P+ A+GS+L G ++GGV + VG +G I LD Sbjct: 54 VAGVVQGASTGASVGMVAGPVGSAIGSLL-GALIGGVVGGTVGQEVGGRIGEQIDQTYLD 112 >UniRef50_A1D9L0 Cluster: Di-, tri-valent inorganic cation transporter, putative; n=2; Trichocomaceae|Rep: Di-, tri-valent inorganic cation transporter, putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 345 Score = 38.7 bits (86), Expect = 0.30 Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 4/90 (4%) Query: 102 TRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQM 161 +RS R+++ IGI+ C FL ++ YT S +L ++ H L D + ++ + K ++ Sbjct: 6 SRSQRLIMV-IGISSCFFLTEISIGLYTHSLALVADAFHYLTDLIGFVVALLAL-KLSEI 63 Query: 162 ADPDH--PYGYTNMRYVSSLISGVGIFCVG 189 DP +G+ + + +G +F +G Sbjct: 64 DDPPKILAFGWQRAPLLGAFFNGALLFALG 93 >UniRef50_Q8TV30 Cluster: Predicted Co/Zn/Cd cation transporter; n=1; Methanopyrus kandleri|Rep: Predicted Co/Zn/Cd cation transporter - Methanopyrus kandleri Length = 293 Score = 38.7 bits (86), Expect = 0.30 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 5/117 (4%) Query: 112 IGINGCNFL--FKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYG 169 IGI G L K+ S +L S+ +HSL DTV+ +++ G + + D H YG Sbjct: 17 IGIYGNILLSVLKIAIGHIASSWALVSDGVHSLGDTVSSVMVLLGAKVARKPPDARHMYG 76 Query: 170 YTNMRYVSSLISGVGIFCVGSG-LSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 + ++ L GV + +G L + + + +P+P LG EG Sbjct: 77 HYKAEALAGL--GVSMMVTFTGLLLLWESLMRLRNPEPPTSTLPLVVALGTVAAKEG 131 >UniRef50_Q7MT89 Cluster: Cation efflux family protein; n=3; Bacteroidales|Rep: Cation efflux family protein - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 302 Score = 38.3 bits (85), Expect = 0.39 Identities = 58/275 (21%), Positives = 120/275 (43%), Gaps = 29/275 (10%) Query: 103 RSGRVV-LTAIGINGCNFLFKLCAWF--YTG-SHSLFSECIHSLADTVNQLILAYGIHKS 158 RS R+ +T +G G N L + +F + G S ++ ++ +HSL+D + ++ I S Sbjct: 10 RSRRIKRITIVGCLG-NLLLTIGKFFSGFVGHSGAMIADAVHSLSDLLTDFVVFIFISIS 68 Query: 159 VQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLG 218 + +D +H YG+ +++ I V + +G+ L G+T + + Y G Sbjct: 69 GKPSDKNHDYGHGKFETLATAIIAVTLIIIGAMLC-SDGLTKV----------YRYLRFG 117 Query: 219 GAVVSEG--ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVL-----LEDTAAVAG 271 + G A LM +S + A+E + V + + S +V+ D Sbjct: 118 DELARPGLIALLMAFVSIV---AKEWLFRITRCVGKEEN-SRSVIANAWHHRSDAYTSVA 173 Query: 272 VIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEIN 331 + C A G + + L + +V + V + + L+ +S+P + +EI Sbjct: 174 TFIGIGC-AFLLGRGWMILEPLSAAVVSVFIIKVGFQMAVPAFRDLLEQSLPDDIEEEIE 232 Query: 332 SVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDG 366 ++ + M++ + ++ +IG N +A++ DG Sbjct: 233 KIICSESMVKGVRRIRTRNIG-NYYAVEADILMDG 266 >UniRef50_Q3ZWB7 Cluster: Cation efflux family protein; n=2; Dehalococcoides|Rep: Cation efflux family protein - Dehalococcoides sp. (strain CBDB1) Length = 316 Score = 38.3 bits (85), Expect = 0.39 Identities = 42/196 (21%), Positives = 88/196 (44%), Gaps = 21/196 (10%) Query: 115 NGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMR 174 +G L + + S +L S+ H L D + + + + ++ + ++ +GY + Sbjct: 28 SGIILLAEFVGGLASNSLALLSDAGHVLTDVLALSLSYFALMQAKRPSNFKMTFGYHRIG 87 Query: 175 YVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSA 234 + ++++ + + + + FY P ++ A+ VL A++ L VAL Sbjct: 88 VLVAILNSISLIGIAVFI-FYESFQRFQSPPEIN----AWLVLPVALLGLATNLAVAL-- 140 Query: 235 IRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALG 294 I ++ N+++ ++ DT A GVI++A + Y+GN L D + Sbjct: 141 ILHSEQKENLNIKSAFWHAAG---------DTLASVGVIISA---VVVIYSGNYLADIIV 188 Query: 295 SILVGTI--LGGVASF 308 S+++G I LGG+ F Sbjct: 189 SVIIGLIISLGGINIF 204 >UniRef50_Q1IPF4 Cluster: Cation diffusion facilitator family transporter; n=1; Acidobacteria bacterium Ellin345|Rep: Cation diffusion facilitator family transporter - Acidobacteria bacterium (strain Ellin345) Length = 483 Score = 38.3 bits (85), Expect = 0.39 Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 4/73 (5%) Query: 108 VLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHP 167 V AI I G K+ YTGS + SE HS D + I I S + AD DH Sbjct: 31 VFAAIFITG----LKVVVGVYTGSLGILSEAAHSGLDLIAAFITFMSIRVSDKPADADHQ 86 Query: 168 YGYTNMRYVSSLI 180 +G+ + S+ I Sbjct: 87 FGHGKVENFSAFI 99 >UniRef50_A3UGA9 Cluster: Cation efflux protein; n=3; Proteobacteria|Rep: Cation efflux protein - Oceanicaulis alexandrii HTCC2633 Length = 321 Score = 38.3 bits (85), Expect = 0.39 Identities = 58/242 (23%), Positives = 108/242 (44%), Gaps = 26/242 (10%) Query: 109 LTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHK-SVQMADPDHP 167 L A + G L ++ TGS +L ++ H L D LILA+G + S + A Sbjct: 44 LIAAALTGGFMLAEVIGGLLTGSLALLADAAHMLTDFA-ALILAWGAFRLSRRPATDKRS 102 Query: 168 YGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGAT 227 YGY ++ +++ +GV + + ++ V + DP + + G +V+ Sbjct: 103 YGYDRLQILAAFANGVTLSILVVWIA-CEAVMRLFDPNEIEATGMMVIAVLGLIVN---- 157 Query: 228 LMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGN 287 +A + GA N+++ R + V LL AA I+AA + + +T Sbjct: 158 --IAAFGVLHGADTDNLNI-----RGALAHVMGDLLGSVAA----IIAAGVIWWTGWT-- 204 Query: 288 PLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVK 347 P+ L ++ G I G++++ ++ + G ++ + P + +D SVL D + I DV Sbjct: 205 PIDPLLSLLIAGLI--GISAWRLVRDAGRVLLEAAP-DHIDP--SVLRAD-LTAEIEDVL 258 Query: 348 GI 349 I Sbjct: 259 DI 260 >UniRef50_A4HFQ2 Cluster: Cation transporter, putative; n=3; Leishmania|Rep: Cation transporter, putative - Leishmania braziliensis Length = 663 Score = 38.3 bits (85), Expect = 0.39 Identities = 47/224 (20%), Positives = 87/224 (38%), Gaps = 17/224 (7%) Query: 131 SHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD-HPYGYTNMRYVSSLISGVGIFCVG 189 S L S+ H + D + +I Y H + + D HP+GY ++G+ + + Sbjct: 393 SLGLVSDSFHMMLDGTSIMIGLYAAHAASWLPDEKTHPFGYARYEVFGGFVNGILLLFIA 452 Query: 190 SGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMV--ALSAIRKGAREANMSLY 247 + V LDP + Y + G V+ L A E Sbjct: 453 LYV-MVESVQRFLDPPEIEGPYLLLVSVTGLAVNVVGVLFFHDAHGHSHSALHEDGGGHV 511 Query: 248 EYVMRSSDPSVNVVLLEDTAAVAGVIVAASCM-AISQYTGNPLPDALGSILVGTILGGVA 306 ++ MR V + +L D VI++++ M + +P+ A+ +ILV ++ Sbjct: 512 DHNMR----GVYLHILADLLGSVSVIISSTLMYMFGLWIADPICSAISAILV-----LLS 562 Query: 307 SFIILSNVGALVGRSIP---HEQLDEINSVLERDFMIRAIHDVK 347 +F +L G ++ S P DE+ VL +++ + K Sbjct: 563 AFPLLEETGRVLLLSAPSYERNYSDELRKVLLETALLQDVESPK 606 >UniRef50_Q6CT16 Cluster: Kluyveromyces lactis strain NRRL Y-1140 chromosome C of strain NRRL Y- 1140 of Kluyveromyces lactis; n=3; Saccharomycetales|Rep: Kluyveromyces lactis strain NRRL Y-1140 chromosome C of strain NRRL Y- 1140 of Kluyveromyces lactis - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 513 Score = 38.3 bits (85), Expect = 0.39 Identities = 19/86 (22%), Positives = 42/86 (48%), Gaps = 2/86 (2%) Query: 131 SHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVG- 189 S +L ++ +H+++D V+ + + + + + D+PYGY + + SL + G Sbjct: 168 SQALIADSVHAISDLVSDFLTLFSVGLATRKPTNDYPYGYGKVETIGSLAVSSILTTAGL 227 Query: 190 -SGLSFYHGVTGILDPQPLHDFYWAY 214 G S + G + P + +F+ A+ Sbjct: 228 SIGWSSLCAIAGPIVPHAILEFFAAH 253 >UniRef50_Q0CAH3 Cluster: Predicted protein; n=1; Aspergillus terreus NIH2624|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 365 Score = 38.3 bits (85), Expect = 0.39 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 3/85 (3%) Query: 112 IGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDH-PYGY 170 IGI+ F+ ++ FYTGS +L ++ H L+D V ++ + + P +G+ Sbjct: 15 IGISTSFFIAEIAVGFYTGSLALVADAFHYLSDIVGFVVALVAAIVEQKSSPPQALTFGW 74 Query: 171 TNMRYVSSLISGVGIFCVGSGLSFY 195 + V + +GV +F G G+S + Sbjct: 75 QRSQLVGAFFNGVLLF--GLGISVF 97 >UniRef50_Q8TP38 Cluster: Cation efflux system protein; n=3; Methanosarcinaceae|Rep: Cation efflux system protein - Methanosarcina acetivorans Length = 411 Score = 38.3 bits (85), Expect = 0.39 Identities = 20/63 (31%), Positives = 32/63 (50%) Query: 127 FYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIF 186 FY+GS SL ++ IH+ D L + G+ S++ ++ PYGY + SL + I Sbjct: 33 FYSGSASLIADAIHTSLDIFTSLAVWIGLKLSMRGSEEKFPYGYYKADNLVSLFVSIIIL 92 Query: 187 CVG 189 G Sbjct: 93 FSG 95 >UniRef50_A0RND9 Cluster: Ferrous-iron efflux pump FieF; n=1; Campylobacter fetus subsp. fetus 82-40|Rep: Ferrous-iron efflux pump FieF - Campylobacter fetus subsp. fetus (strain 82-40) Length = 291 Score = 37.9 bits (84), Expect = 0.52 Identities = 51/234 (21%), Positives = 95/234 (40%), Gaps = 28/234 (11%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 + K +GS ++ S I SL D + + + + KS + +GY + + +L Sbjct: 18 IIKFAIGLASGSMAVLSSAIDSLLDCLVSALNYFALRKSNSDPNSKFNFGYGKIEALVAL 77 Query: 180 ISGVGIFCVGSGLSF-YHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKG 238 G F +G G+ Y VT I++P+ V G +M+ +S I G Sbjct: 78 FEGA--FIIGIGIFICYSSVTKIINPEK------------SIEVGAGMIVMI-ISIILTG 122 Query: 239 AREANMSLYEYVMRSSDPSVNVVLLED-----TAAVAGVIVAASCMAISQYTGNPLPDAL 293 A L Y+ R + N+++ D T V + A+ AI +G + DAL Sbjct: 123 A------LVFYLQREYKKTGNLIIKADALHYQTDLVTNAAILAALFAI-WLSGYDIIDAL 175 Query: 294 GSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVK 347 I + + A ++ V L+ ++P + I ++ +++ H +K Sbjct: 176 FGIGISVYIVFSAFKLLKEGVYILLDGALPESMVSGIIDIINLKHEVKSYHYLK 229 >UniRef50_A0IKN6 Cluster: Cation diffusion facilitator family transporter; n=1; Serratia proteamaculans 568|Rep: Cation diffusion facilitator family transporter - Serratia proteamaculans 568 Length = 460 Score = 37.9 bits (84), Expect = 0.52 Identities = 20/58 (34%), Positives = 30/58 (51%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 K A +TGS L SE IHS D + I + S + AD DH +G+ + +++L Sbjct: 23 KFIAGIFTGSIGLISEGIHSFTDFIATSITWLAVRISDKPADDDHHFGHGKVENLAAL 80 >UniRef50_Q7NIC0 Cluster: Gll2263 protein; n=2; Cyanobacteria|Rep: Gll2263 protein - Gloeobacter violaceus Length = 247 Score = 37.5 bits (83), Expect = 0.69 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Query: 269 VAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLD 328 + G++V +AI ALG+ L T+ GG VGALVG IP E+ + Sbjct: 78 LTGLLVGIGALAIPGIGPVITAGALGTALATTLAGGAIGAAAGGLVGALVGLGIPKERAE 137 Query: 329 EINSVLER-DFMI 340 N+ + R D+++ Sbjct: 138 VYNAAVTRGDYLV 150 >UniRef50_Q749X9 Cluster: Cation efflux family protein; n=8; Deltaproteobacteria|Rep: Cation efflux family protein - Geobacter sulfurreducens Length = 296 Score = 37.5 bits (83), Expect = 0.69 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 5/89 (5%) Query: 103 RSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMA 162 R+ +V+ +N + KL A + GS ++F++ + S D V L + + Sbjct: 9 RAEKVIHLGFWVNAVLMVMKLAAGHFGGSEAVFADGVESGCDFVALLFTMVALRVGRKPF 68 Query: 163 DPDHPYGYTNMRYVSS-----LISGVGIF 186 D HPYG+ V++ +I G G+F Sbjct: 69 DARHPYGHGKAENVAAFVIALVIGGAGMF 97 >UniRef50_Q6LGB2 Cluster: Hypothetical cation-efflux family protein; n=4; Vibrionaceae|Rep: Hypothetical cation-efflux family protein - Photobacterium profundum (Photobacterium sp. (strain SS9)) Length = 275 Score = 37.5 bits (83), Expect = 0.69 Identities = 16/61 (26%), Positives = 31/61 (50%) Query: 134 LFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLS 193 + ++ +HS +D V + G AD +HPYG+ ++++ GV + VG G+ Sbjct: 1 MIADGVHSFSDLVTDTAILIGSRYWTAPADKEHPYGHGRFETLTNIFIGVILAIVGIGIG 60 Query: 194 F 194 + Sbjct: 61 W 61 >UniRef50_Q2S288 Cluster: Cation efflux family protein; n=1; Salinibacter ruber DSM 13855|Rep: Cation efflux family protein - Salinibacter ruber (strain DSM 13855) Length = 324 Score = 37.5 bits (83), Expect = 0.69 Identities = 50/229 (21%), Positives = 91/229 (39%), Gaps = 20/229 (8%) Query: 122 KLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLIS 181 KL A TGS ++ S+ S+ + + + D +HPYG+ + Y +S + Sbjct: 37 KLTAASLTGSTAILSDAAESVIHLFATGFAGFSLWYASTPPDVEHPYGHGKVAYFASAVE 96 Query: 182 GVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGARE 241 G I G+ + V ++ L +++GG + +R G R Sbjct: 97 GTLILAAAVGIG-WMAVQDLVTGADLRQLDVGLYLIGGLT---AVNFALGTYLVRVGRRT 152 Query: 242 ANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTI 301 ++ V+ S+ V L D GVIV + I TG D +LV Sbjct: 153 NSL-----VLESNGEHV----LTDMWTSLGVIVGIGLVWI---TGIRWLDPAVGLLVAAN 200 Query: 302 LGGVASFIILSNVGALVGRS---IPHEQLDEINSVLERDFMIRAIHDVK 347 + A+ ++ +V L+ + LDE+ + +E + +I + H V+ Sbjct: 201 IVWTATGLLRRSVYGLMDEADWEASSALLDELGTAVE-EGLIASFHQVR 248 >UniRef50_Q2LWF9 Cluster: Co/Zn/Cd cation transporter; n=1; Syntrophus aciditrophicus SB|Rep: Co/Zn/Cd cation transporter - Syntrophus aciditrophicus (strain SB) Length = 421 Score = 37.5 bits (83), Expect = 0.69 Identities = 64/251 (25%), Positives = 105/251 (41%), Gaps = 20/251 (7%) Query: 105 GRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADP 164 G+V L A +N K F++ S ++ + I S D+ L+L G+ S + P Sbjct: 28 GKVALYAFLLNLGLAAMKGVLAFWSDSLAVTAGAIDSATDSAASLVLYGGLKLSTRKT-P 86 Query: 165 DHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSE 224 P G + V S+ + IF G ++ + P+ D VL +VS Sbjct: 87 SFPEGLYKIENVLSVFVALSIFFAGLEIALKLFKQSVSSPRISLDIV----VL--LLVSV 140 Query: 225 GATLMVALSAIRKGAREANMSLY-EYVMRSSDP-SVNVVLLEDTAAVAGVIVAASCMAIS 282 AT + AI G + + +L E R D S +VVL+ G V+ ++I Sbjct: 141 AATFLFGRYAILTGRKTESPTLIAEGRHRQVDVLSSSVVLISVLPEYFGYHVSLFGLSI- 199 Query: 283 QYTGNPLPDALGSILVGTILGGVASFIILSN-VGALVGRSIPHEQLDEINSVLERDFMIR 341 D++ + V I A + +LSN + L+ S+ E LDE S+L+ M+ Sbjct: 200 --------DSIAACAV-LIFIAFAGWELLSNGMRVLLDASLDFETLDEARSILKNHPMVV 250 Query: 342 AIHDVKGIDIG 352 I + G + G Sbjct: 251 NIRSLSGRNAG 261 >UniRef50_A5G751 Cluster: Cation diffusion facilitator family transporter; n=1; Geobacter uraniumreducens Rf4|Rep: Cation diffusion facilitator family transporter - Geobacter uraniumreducens Rf4 Length = 293 Score = 37.5 bits (83), Expect = 0.69 Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 1/117 (0%) Query: 114 INGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNM 173 +N C L +L +T S ++ S +H L D ++ + Y + + +D + YGY Sbjct: 20 LNLCFTLLELFGGLWTNSIAIISNAVHDLGDCLSLGLAWYLAGYAEKESDRRYSYGYRRF 79 Query: 174 RYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMV 230 + +L + + + VGS L V +L P+ + A + G V+ A L V Sbjct: 80 SLLGALATAL-VLMVGSLLVLSEAVPRLLRPEHPNAGGMALLAVVGIAVNGLALLRV 135 >UniRef50_A3TRN3 Cluster: Tyrosine protein kinase:Serine/threonine protein kinase; n=1; Janibacter sp. HTCC2649|Rep: Tyrosine protein kinase:Serine/threonine protein kinase - Janibacter sp. HTCC2649 Length = 583 Score = 37.5 bits (83), Expect = 0.69 Identities = 18/41 (43%), Positives = 26/41 (63%) Query: 268 AVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASF 308 AV+GV AA + Q TG+P PDAL + VG +L G+ ++ Sbjct: 477 AVSGVFCAALAVVAIQGTGSPEPDALAPLAVGGLLAGLMAW 517 >UniRef50_A0LKX9 Cluster: Cation diffusion facilitator family transporter; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Cation diffusion facilitator family transporter - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 307 Score = 37.5 bits (83), Expect = 0.69 Identities = 20/75 (26%), Positives = 35/75 (46%) Query: 120 LFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSL 179 + KL T S + +E +HS D + +I + + S + AD H YG+ + VS + Sbjct: 22 VLKLVVGIMTQSVGVIAEAVHSGLDLLAAVIAWFSVRASGKPADDRHRYGHGQIESVSGV 81 Query: 180 ISGVGIFCVGSGLSF 194 + + IF + F Sbjct: 82 VEALLIFAAAGCIIF 96 >UniRef50_Q4WLB1 Cluster: CDF zinc transporter (Msc2), putaitve; n=7; Eurotiomycetidae|Rep: CDF zinc transporter (Msc2), putaitve - Aspergillus fumigatus (Sartorya fumigata) Length = 877 Score = 37.5 bits (83), Expect = 0.69 Identities = 48/206 (23%), Positives = 85/206 (41%), Gaps = 16/206 (7%) Query: 100 LKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSV 159 LK R R + + +N L +L F TGS L S+ IH D L L G+ +V Sbjct: 510 LKERDSRRIFYFMTLNFTFMLVQLSYGFITGSLGLLSDSIHMFFDC---LALVVGLCAAV 566 Query: 160 QMADPD---HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFV 216 P PYGY + +S +G+ + + + Y V + +H V Sbjct: 567 MSKWPSSARFPYGYGKVDTLSGFANGIFLMIISIEI-IYEAVERLSSGSQMHRLGELLAV 625 Query: 217 -LGGAVVSEGATLMVALSAIRKG-AREANMSLYEYVMRSSD-PSVNVVLLEDTAAVAGVI 273 + G VV+ +V + A G A + + + + + + + +L DT V+ Sbjct: 626 SVAGLVVN-----LVGIMAFDHGHAHHGHDHGHSHSHGNENMHGIFLHILADTLGSVAVV 680 Query: 274 VAASCMAISQYTG-NPLPDALGSILV 298 ++ + S + G +P+ L +IL+ Sbjct: 681 ISTILVHFSGWAGYDPIASCLIAILI 706 >UniRef50_Q2FN36 Cluster: Cation diffusion facilitator family transporter; n=1; Methanospirillum hungatei JF-1|Rep: Cation diffusion facilitator family transporter - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 344 Score = 37.5 bits (83), Expect = 0.69 Identities = 58/290 (20%), Positives = 127/290 (43%), Gaps = 20/290 (6%) Query: 86 MSHTRSKDNVE--EVGLKTRSGRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLA 143 M H +S++ ++ E+ ++ RV+ ++ I+ ++ L +GS +L +E I Sbjct: 31 MVHVQSEEEIKSSEIRMQRLKERVIFKSLIIDTIFWIPSLILAGMSGSVTLSTEAIKKGN 90 Query: 144 DTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILD 203 + ++ + K Q + YG ++ +++G+ + + L F V +L+ Sbjct: 91 EILSTFFAWLALKKMSQGGAHAYDYGMGKFENMTGIVTGI-VMILSLVLVFGLTVLKLLN 149 Query: 204 PQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLL 263 P LH+ ++ V+ G + V+ R+ A M Y V+ + + L Sbjct: 150 PHMLHE---EVTIVAMIVMFTG--ICVSTILWREKVHIAKME-YSPVIEAQ------ITL 197 Query: 264 EDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILG--GVASF-IILSNVGALVGR 320 T A+ +V A+ + + NP D + + ++G ++ + I S++ L+ + Sbjct: 198 FKTKAITEFVVLAALLLVLFIEDNPWEDYIDPVASFIVIGLFLLSGYRTISSSLPDLLDK 257 Query: 321 SIPHE-QLDEINSVLERDFMIRAIHDVKGIDIGSNLIRYKAEVDFDGRAL 369 +I E QL + S+ + A H V+ G+++ + ++FDG L Sbjct: 258 TIEEELQLVVVRSLADFFDEYEAFHGVRSRKCGNDIF-IELFLEFDGNRL 306 >UniRef50_O27915 Cluster: Cation efflux system protein; n=1; Methanothermobacter thermautotrophicus str. Delta H|Rep: Cation efflux system protein - Methanobacterium thermoautotrophicum Length = 298 Score = 37.5 bits (83), Expect = 0.69 Identities = 67/306 (21%), Positives = 120/306 (39%), Gaps = 34/306 (11%) Query: 106 RVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPD 165 R IG N +GS +L +E H+L+D + +I G + D Sbjct: 12 RAAFAGIGGNVLLTSLNFLVGISSGSVALVAEAAHTLSDVLTSVITYIGFRIGQRPPDRQ 71 Query: 166 HPYGYTNMRYVSSLISGVGIFCVGSGLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEG 225 HPYG+ + L+ V +F GI+ + L + Y F L A Sbjct: 72 HPYGHGRAEALVGLV--VVVF------------LGIISYEILSEAYRKLF-LELAPPDYT 116 Query: 226 ATLMVALSAIRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAI---- 281 A LM I AN+++ Y+ R + + ++ D A + SC+AI Sbjct: 117 AALMAGFGII------ANIAMTTYIRRIGERINSPAIVAD--AQHQKVDIFSCIAIMLGV 168 Query: 282 -SQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMI 340 + G D L ++++ ++ A + NV ++G E +++I + Sbjct: 169 AGSHLGLRFLDPLVAVIIAVLVLKTAFDVGRENVNNILGAVPSPEIMEDIEKSAMSVDGV 228 Query: 341 RAIHDVKGIDIGSNLIRYKAEVDFDGRALTR-SYLEKHDL-NALLEDMKKIDTIDDVETF 398 + +H+V+ I+ ++ DG + R ++ HD+ ++ED ID I V Sbjct: 229 KGLHEVR-INHFGPYASVDLHIEVDGDMMLRDAHRIAHDVERRVIED---IDIIKIVNVH 284 Query: 399 LLKHGE 404 + GE Sbjct: 285 VCPVGE 290 >UniRef50_A5UNR6 Cluster: Heavy metal cation (Co/Zn/Cd) efflux system protein, CzcD family; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Heavy metal cation (Co/Zn/Cd) efflux system protein, CzcD family - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 299 Score = 37.5 bits (83), Expect = 0.69 Identities = 18/76 (23%), Positives = 41/76 (53%), Gaps = 1/76 (1%) Query: 129 TGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCV 188 T S ++ ++C+H L+DT++ + H S + + ++ YGY + ++I+ + + V Sbjct: 38 TNSVAILADCLHDLSDTISIGLAGVLEHVSQKNPNENYTYGYQRFSILGAVITSIFVIIV 97 Query: 189 GSGLSFYHGVTGILDP 204 S + Y ++ +L P Sbjct: 98 -SVVVVYESISRLLCP 112 >UniRef50_Q08970 Cluster: Mitochondrial metal transporter 2, mitochondrial precursor; n=2; Saccharomyces cerevisiae|Rep: Mitochondrial metal transporter 2, mitochondrial precursor - Saccharomyces cerevisiae (Baker's yeast) Length = 449 Score = 37.5 bits (83), Expect = 0.69 Identities = 58/276 (21%), Positives = 111/276 (40%), Gaps = 19/276 (6%) Query: 77 RRLRDYRREMSHTRSKDN----VEEVGLKTRSG-RVVLTAIGINGCNFLFKLCAWFYTGS 131 + L + SHT DN + +K G R+ + N + K S Sbjct: 97 KSLLQHTHSHSHTHMHDNPLLSLNVQQIKKNPGVRITWIGLASNVGMAVGKFVGGITFHS 156 Query: 132 HSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGSG 191 +L ++ +H+L+D V+ + + + + + ++PYGY + V SL V +G Sbjct: 157 QALLADSVHALSDLVSDFLTLFSVQYASRKPTSEYPYGYGKVETVGSL--AVSTILAMAG 214 Query: 192 LSF-YHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATL-MVALSAIRKGAREANMSLYEY 249 +S + + I+ P H + L G S +L A + ++ + E+ Sbjct: 215 ISIGWSSLCAIVGPVIPHAILESMAGLIGETHSHSQSLTQQATNVNAVWIAAGSILVKEW 274 Query: 250 VMRSS-----DPSVNVVLL---EDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTI 301 V +++ + NV++ +VA + S + D LG ++V + Sbjct: 275 VFQATKKVAIQTNSNVLMANAWHHRVDSLTSLVALVAITSSYFFNIQSLDNLGGLVVSGL 334 Query: 302 LGGVASFIILSNVGALVGRSIP--HEQLDEINSVLE 335 + ILS++ LV +SIP + EI SV++ Sbjct: 335 IIKTGGQGILSSLKELVDQSIPPTDPRYLEIESVIK 370 >UniRef50_UPI0000DAE7E5 Cluster: hypothetical protein Rgryl_01001288; n=1; Rickettsiella grylli|Rep: hypothetical protein Rgryl_01001288 - Rickettsiella grylli Length = 374 Score = 37.1 bits (82), Expect = 0.91 Identities = 42/225 (18%), Positives = 99/225 (44%), Gaps = 16/225 (7%) Query: 131 SHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGS 190 SH L ++ +HSL+D + L++ + AD +HPYG+ + ++++ + + + + Sbjct: 36 SHGLLADGVHSLSDLMVDLLVIIASKFGNKAADENHPYGHGRIETAATVLLAI-LLALAA 94 Query: 191 GLSFYHGVTGILDPQPLHDFYWAYFVLGGAVVSEGATLMVALSAIRKGAREANMSLYEYV 250 + VT I +H + L +ALS+I + + + Sbjct: 95 LAIIVNAVTTI---HRIH----------VKEIPSQIVLWIALSSILLNELIYFWTKHIAI 141 Query: 251 MRSSDPSVNVVLLEDTAAVAGVIVAASCMAISQYTGNPLPDALGSILVGTILGGVASFII 310 S+ ++ + + + + VA + + G P DA+ +I+VG ++ A Sbjct: 142 QIKSNLLMSNAWHHRSDSFSSMAVAFG--VVGAWLGFPKLDAVAAIVVGLMILKTAWNFG 199 Query: 311 LSNVGALVGRSIPHEQLDEINSVLERDFMIRAIHDVKGIDIGSNL 355 ++ LV ++ E+ ++I +++ ++AIH ++ I ++ Sbjct: 200 WYSIRELVDTALSTEETEKIKRFIKKVSGVKAIHQLRTRSIAGSI 244 >UniRef50_Q8FU00 Cluster: Putative uncharacterized protein; n=1; Corynebacterium efficiens|Rep: Putative uncharacterized protein - Corynebacterium efficiens Length = 333 Score = 37.1 bits (82), Expect = 0.91 Identities = 18/69 (26%), Positives = 32/69 (46%) Query: 131 SHSLFSECIHSLADTVNQLILAYGIHKSVQMADPDHPYGYTNMRYVSSLISGVGIFCVGS 190 S ++ + + L V L G+ + + A P HPYGY ++ L+SG+ + G Sbjct: 48 SQAMQAAWVQDLLGMVPPLAFLIGVKVARRRASPAHPYGYAQSMDIAHLVSGIALTAFGG 107 Query: 191 GLSFYHGVT 199 L + +T Sbjct: 108 FLVYESTMT 116 >UniRef50_Q606W3 Cluster: Cation efflux family protein; n=2; Bacteria|Rep: Cation efflux family protein - Methylococcus capsulatus Length = 314 Score = 37.1 bits (82), Expect = 0.91 Identities = 59/252 (23%), Positives = 113/252 (44%), Gaps = 29/252 (11%) Query: 105 GRVVLTAIGINGCNFLFKLCAWFYTGSHSLFSECIHSLADTVNQLILAYGIHKSVQMADP 164 GR+V I + G +F+ A + S +L ++ +H+L+D + + Y + + Q A Sbjct: 19 GRLVWALI-LTGGFVVFEALAGWKANSLALLTDAVHNLSDVLALGLSWYAMRLTAQPAHA 77 Query: 165 DHPYGYTNMRYVSSLISGVGIFCVGSGL-SFYHGVTGILDPQPLHDFYWAYFVLGGAVVS 223 +GY +++L + G+ VG L Y +L P P+ A ++G V Sbjct: 78 AKTFGYHRAGILAALANSAGL--VGVALYILYDAYVRLLSPAPVQ----ADILIG---VG 128 Query: 224 EGATLMVALSA--IRKGAREANMSLYEYVMRSSDPSVNVVLLEDTAAVAGVIVAASCMAI 281 A L+ A +A + G+ + + MRS+ + LL D + G I A +AI Sbjct: 129 GAALLVNAFTAWLVHHGSHD------DLNMRSA----FLHLLGDVVSTLGAIAAG--VAI 176 Query: 282 SQYTGNPLPDALGSILVGTILGGVASFIILSNVGALVGRSIPHEQLDEINSVLERDFMIR 341 +YTG D S+L+ ++ A +++ V ++ S P + ++ S++ + Sbjct: 177 -RYTGLYWLDPAVSVLIALLILWNAKG-LMAEVMDILLESTPRDV--DMGSMVRDMMQVE 232 Query: 342 AIHDVKGIDIGS 353 +H V + + S Sbjct: 233 GVHGVHHLHVWS 244 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.322 0.139 0.405 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 453,074,260 Number of Sequences: 1657284 Number of extensions: 18210965 Number of successful extensions: 50340 Number of sequences better than 10.0: 312 Number of HSP's better than 10.0 without gapping: 220 Number of HSP's successfully gapped in prelim test: 92 Number of HSP's that attempted gapping in prelim test: 49969 Number of HSP's gapped (non-prelim): 393 length of query: 436 length of database: 575,637,011 effective HSP length: 103 effective length of query: 333 effective length of database: 404,936,759 effective search space: 134843940747 effective search space used: 134843940747 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.9 bits) S2: 74 (33.9 bits)
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