Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000937-TA|BGIBMGA000937-PA|IPR000257|Uroporphyrinogen
decarboxylase (URO-D), IPR006361|Uroporphyrinogen decarboxylase HemE
(310 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000DB7C9D Cluster: PREDICTED: similar to Updo CG181... 318 1e-85
UniRef50_A4CHM1 Cluster: Uroporphyrinogen decarboxylase; n=15; B... 252 6e-66
UniRef50_O18601 Cluster: Uroporphyrinogen decarboxylase; n=9; Fu... 249 6e-65
UniRef50_Q9V595 Cluster: Uroporphyrinogen decarboxylase; n=35; c... 246 4e-64
UniRef50_UPI00015B4317 Cluster: PREDICTED: similar to ENSANGP000... 229 9e-59
UniRef50_P06132 Cluster: Uroporphyrinogen decarboxylase; n=29; F... 198 1e-49
UniRef50_Q9USJ5 Cluster: Uroporphyrinogen decarboxylase; n=24; F... 184 3e-45
UniRef50_P32347 Cluster: Uroporphyrinogen decarboxylase; n=4; Fu... 179 7e-44
UniRef50_Q83EP0 Cluster: Uroporphyrinogen decarboxylase; n=4; Co... 162 9e-39
UniRef50_Q23DD3 Cluster: Uroporphyrinogen decarboxylase family p... 155 2e-36
UniRef50_A0Q8F6 Cluster: Uroporphyrinogen decarboxylase; n=11; F... 147 4e-34
UniRef50_A3HYD0 Cluster: Uroporphyrinogen decarboxylase; n=1; Al... 146 5e-34
UniRef50_A7H9E0 Cluster: Uroporphyrinogen decarboxylase; n=2; An... 146 6e-34
UniRef50_A3ERP3 Cluster: Uroporphyrinogen decarboxylase; n=1; Le... 146 8e-34
UniRef50_Q8KAW2 Cluster: Uroporphyrinogen decarboxylase; n=11; B... 143 4e-33
UniRef50_A0C9P3 Cluster: Uroporphyrinogen decarboxylase; n=3; Pa... 142 8e-33
UniRef50_Q8CWI5 Cluster: Uroporphyrinogen decarboxylase; n=1; Wi... 136 9e-31
UniRef50_A6EES3 Cluster: Uroporphyrinogen decarboxylase; n=1; Pe... 134 3e-30
UniRef50_Q6ANR5 Cluster: Uroporphyrinogen decarboxylase; n=6; De... 132 8e-30
UniRef50_Q1ENA9 Cluster: Uroporphyrinogen decarboxylase precurso... 132 1e-29
UniRef50_A5K1S0 Cluster: Uroporphyrinogen decarboxylase, putativ... 132 1e-29
UniRef50_A6QAQ4 Cluster: Uroporphyrinogen decarboxylase; n=4; Ep... 127 3e-28
UniRef50_A0GXY8 Cluster: Uroporphyrinogen decarboxylase; n=2; Ch... 126 5e-28
UniRef50_Q89SK1 Cluster: Uroporphyrinogen decarboxylase; n=23; P... 126 7e-28
UniRef50_A5EDY0 Cluster: Uroporphyrinogen decarboxylase; n=20; A... 126 1e-27
UniRef50_Q8FY24 Cluster: Uroporphyrinogen decarboxylase; n=12; A... 125 1e-27
UniRef50_A6GDP1 Cluster: Uroporphyrinogen decarboxylase; n=1; Pl... 125 2e-27
UniRef50_Q6MB12 Cluster: Uroporphyrinogen decarboxylase; n=1; Ca... 123 5e-27
UniRef50_Q01W10 Cluster: Uroporphyrinogen decarboxylase; n=1; So... 122 2e-26
UniRef50_Q83H92 Cluster: Uroporphyrinogen decarboxylase; n=2; Tr... 121 3e-26
UniRef50_O22886 Cluster: Uroporphyrinogen decarboxylase, chlorop... 120 5e-26
UniRef50_Q8XU90 Cluster: Uroporphyrinogen decarboxylase; n=258; ... 119 8e-26
UniRef50_Q9RV96 Cluster: Uroporphyrinogen decarboxylase; n=2; De... 119 8e-26
UniRef50_Q5FS38 Cluster: Uroporphyrinogen decarboxylase; n=6; Al... 119 1e-25
UniRef50_Q6AHF5 Cluster: Uroporphyrinogen decarboxylase; n=4; Ba... 118 1e-25
UniRef50_Q8FSD6 Cluster: Uroporphyrinogen decarboxylase; n=3; Co... 116 8e-25
UniRef50_Q7VF06 Cluster: Uroporphyrinogen decarboxylase; n=23; C... 114 3e-24
UniRef50_Q0BWA4 Cluster: Uroporphyrinogen decarboxylase; n=2; Al... 113 4e-24
UniRef50_A6DLM9 Cluster: Uroporphyrinogen decarboxylase; n=1; Le... 112 1e-23
UniRef50_Q42855 Cluster: Uroporphyrinogen decarboxylase; n=10; M... 112 1e-23
UniRef50_Q59269 Cluster: Uroporphyrinogen decarboxylase; n=4; Al... 112 1e-23
UniRef50_Q15GC6 Cluster: Uroporphyrinogen decarboxylase; n=1; Gu... 111 2e-23
UniRef50_Q019R2 Cluster: Uroporphyrinogen decarboxylase; n=2; Os... 109 7e-23
UniRef50_Q1ITV2 Cluster: Uroporphyrinogen decarboxylase; n=5; Ba... 109 1e-22
UniRef50_Q01G98 Cluster: Uroporphyrinogen decarboxylase; n=2; Os... 109 1e-22
UniRef50_A3VQ61 Cluster: Uroporphyrinogen decarboxylase; n=1; Pa... 108 2e-22
UniRef50_P42503 Cluster: Uroporphyrinogen decarboxylase; n=14; A... 108 2e-22
UniRef50_Q5L284 Cluster: Uroporphyrinogen decarboxylase; n=5; Ba... 107 4e-22
UniRef50_Q2GCG4 Cluster: Uroporphyrinogen decarboxylase; n=1; Ne... 107 4e-22
UniRef50_P32395 Cluster: Uroporphyrinogen decarboxylase; n=52; B... 106 6e-22
UniRef50_Q7UN37 Cluster: Uroporphyrinogen III synthase, uroporhy... 106 8e-22
UniRef50_Q8NT75 Cluster: Uroporphyrinogen decarboxylase; n=45; B... 106 8e-22
UniRef50_Q2GLU4 Cluster: Uroporphyrinogen decarboxylase; n=2; An... 105 1e-21
UniRef50_A5H0C9 Cluster: Uroporphyrinogen decarboxylase; n=39; R... 103 8e-21
UniRef50_Q92FV3 Cluster: Uroporphyrinogen decarboxylase; n=10; R... 103 8e-21
UniRef50_A5CDS4 Cluster: Uroporphyrinogen decarboxylase; n=1; Or... 102 1e-20
UniRef50_Q7U645 Cluster: Uroporphyrinogen decarboxylase; n=44; c... 101 2e-20
UniRef50_UPI00015BC740 Cluster: UPI00015BC740 related cluster; n... 100 4e-20
UniRef50_Q6KZ54 Cluster: Uroporphyrinogen decarboxylase; n=2; Th... 100 5e-20
UniRef50_O66667 Cluster: Uroporphyrinogen decarboxylase; n=1; Aq... 99 1e-19
UniRef50_Q8EY41 Cluster: Uroporphyrinogen decarboxylase; n=5; Ba... 95 3e-18
UniRef50_Q1V1A2 Cluster: Uroporphyrinogen decarboxylase; n=2; Ca... 89 1e-16
UniRef50_A2ZVI4 Cluster: Uroporphyrinogen decarboxylase; n=2; Or... 81 3e-14
UniRef50_Q9HLB9 Cluster: Uroporphyrinogen decarboxylase; n=2; Th... 80 8e-14
UniRef50_A7BNH3 Cluster: Uroporphyrinogen decarboxylase; n=1; Be... 72 2e-11
UniRef50_O84752 Cluster: Uroporphyrinogen decarboxylase; n=8; Ch... 57 7e-07
UniRef50_A5I1W7 Cluster: Putative methylcobamide:CoM methyltrans... 52 1e-05
UniRef50_Q024B9 Cluster: Uroporphyrinogen decarboxylase; n=1; So... 50 6e-05
UniRef50_A3DJ55 Cluster: Methyltransferase MtaA/CmuA family; n=2... 49 2e-04
UniRef50_Q0AZU9 Cluster: Uroporphyrinogen decarboxylase; n=1; Sy... 48 4e-04
UniRef50_Q6LYZ9 Cluster: Uroporphyrinogen decarboxylase; n=6; Me... 47 5e-04
UniRef50_Q8PXZ6 Cluster: Methylcobalamin: Coenzyme M methyltrans... 46 0.002
UniRef50_A6R5E7 Cluster: Predicted protein; n=1; Ajellomyces cap... 45 0.003
UniRef50_Q0YLK8 Cluster: Uroporphyrinogen decarboxylase; n=1; Ge... 44 0.004
UniRef50_Q70E94 Cluster: Methylcobalamin:coenzyme M methyltransf... 44 0.005
UniRef50_Q8AAW9 Cluster: Methylcobamide:CoM methyltransferase mt... 44 0.007
UniRef50_A6PPN3 Cluster: Uroporphyrinogen decarboxylase; n=1; Vi... 43 0.009
UniRef50_Q18UN1 Cluster: Uroporphyrinogen decarboxylase; n=2; De... 42 0.020
UniRef50_A6BKM2 Cluster: Putative uncharacterized protein; n=1; ... 42 0.020
UniRef50_Q8PZI7 Cluster: Methylcobalamin:Coenzyme M methyltransf... 42 0.027
UniRef50_Q2RIW2 Cluster: Putative uncharacterized protein; n=3; ... 40 0.062
UniRef50_Q2RLD3 Cluster: Uroporphyrinogen decarboxylase; n=1; Mo... 40 0.081
UniRef50_Q2RG09 Cluster: Uroporphyrinogen decarboxylase; n=1; Mo... 40 0.11
UniRef50_Q0AZU7 Cluster: Uroporphyrinogen decarboxylase; n=1; Sy... 39 0.14
UniRef50_A7CVU8 Cluster: Uroporphyrinogen decarboxylase HemE; n=... 39 0.19
UniRef50_A5I1X6 Cluster: Putative methylcobamide:CoM methyltrans... 38 0.43
UniRef50_Q8THF8 Cluster: Methylcobamide:CoM methyltransferase is... 36 1.0
UniRef50_Q5JEA5 Cluster: Hypothetical membrane protein, conserve... 36 1.3
UniRef50_O67753 Cluster: Type III pantothenate kinase; n=1; Aqui... 36 1.3
UniRef50_UPI00015557E4 Cluster: PREDICTED: similar to T cell rec... 35 2.3
UniRef50_Q2RG07 Cluster: Methyltransferase MtaA/CmuA; n=2; Moore... 35 2.3
UniRef50_Q0LDB2 Cluster: Putative uncharacterized protein; n=1; ... 35 2.3
UniRef50_A5GK46 Cluster: Possible thiopurine S-methyltransferase... 35 3.1
UniRef50_Q01R38 Cluster: Putative methyltransferase CmuC; n=1; S... 34 4.0
UniRef50_A6PSC8 Cluster: Regulatory protein GntR, HTH; n=1; Vict... 34 4.0
UniRef50_UPI00006600F2 Cluster: Zinc fingers and homeoboxes prot... 34 5.3
UniRef50_O74539 Cluster: Peroxide stress-activated histidine kin... 34 5.3
UniRef50_UPI000038CE2D Cluster: COG3321: Polyketide synthase mod... 33 7.1
UniRef50_Q2F9X4 Cluster: Putative uncharacterized protein; n=1; ... 33 7.1
UniRef50_Q11FK7 Cluster: Molybdopterin binding domain; n=4; Rhiz... 33 7.1
UniRef50_A7CT59 Cluster: Putative uncharacterized protein; n=1; ... 33 7.1
UniRef50_A4QTQ9 Cluster: Putative uncharacterized protein; n=1; ... 33 7.1
UniRef50_Q2NG99 Cluster: MtaA1; n=1; Methanosphaera stadtmanae D... 33 7.1
UniRef50_UPI00015B4E9B Cluster: PREDICTED: similar to leukocyte ... 33 9.3
UniRef50_A0BYF6 Cluster: Chromosome undetermined scaffold_137, w... 33 9.3
UniRef50_A7TLW4 Cluster: Putative uncharacterized protein; n=1; ... 33 9.3
>UniRef50_UPI0000DB7C9D Cluster: PREDICTED: similar to Updo
CG1818-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
to Updo CG1818-PA - Apis mellifera
Length = 322
Score = 318 bits (781), Expect = 1e-85
Identities = 164/317 (51%), Positives = 217/317 (68%), Gaps = 19/317 (5%)
Query: 8 FPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTL 67
FP LKND +L+A G+S +++P+W+MRQAGRYLPEFQE+R KHDFF++C+TP LACEVTL
Sbjct: 6 FPPLKNDLILKAIRGESTERIPIWIMRQAGRYLPEFQEIRSKHDFFSICQTPTLACEVTL 65
Query: 68 QPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSR 127
QP++R++ LDA IIFSDILVIPQA+G+TVEM PG+GPV PKPL+ P+++ L
Sbjct: 66 QPIKRFD-LDAGIIFSDILVIPQAMGLTVEMIPGMGPVLPKPLKDPTDLVRLIQPNVEKD 124
Query: 128 LDYVGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQVFESSA--------------DHL 173
L YVG AITLTR+K++GKVPLIGFTGA + ++Q SS H
Sbjct: 125 LKYVGDAITLTRYKLEGKVPLIGFTGAAWTLMSYMIQGGGSSTMIRAREWLYKYPDDSHK 184
Query: 174 SREQFTEFSIPYL-KDIRSGVRAKLTEKSLEQVPMTIFAKGAG-HSLDIQAQ-LGYETIG 230
+ T I YL +++G + +L ++++ +VPM F KGA +SL++ A+ YE +G
Sbjct: 185 LLQLITNVIIDYLVMQVKAGAQ-RLKKENIPEVPMIAFPKGATINSLEMLAKSKTYEVLG 243
Query: 231 LDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVKKFGKHRYIANLGHGI 290
LDWT+DP EARK G I LQGN DP LY + +EI +M KFGK RYIANLGHGI
Sbjct: 244 LDWTIDPIEARKKFGSEIILQGNFDPCALYGSEQEIINRAKDMALKFGKIRYIANLGHGI 303
Query: 291 TPQTPLESMTVFTETVH 307
P TP+ S+T F + +H
Sbjct: 304 LPDTPIASVTAFIKGIH 320
>UniRef50_A4CHM1 Cluster: Uroporphyrinogen decarboxylase; n=15;
Bacteroidetes|Rep: Uroporphyrinogen decarboxylase -
Robiginitalea biformata HTCC2501
Length = 349
Score = 252 bits (618), Expect = 6e-66
Identities = 137/334 (41%), Positives = 198/334 (59%), Gaps = 41/334 (12%)
Query: 13 NDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRR 72
ND L+A G++V++ PVW+MRQAGRYLPEF E++ K+DFFT C+TPELA E+T+QP+RR
Sbjct: 10 NDLFLKALRGETVERPPVWMMRQAGRYLPEFMEIKKKYDFFTRCQTPELASEITVQPIRR 69
Query: 73 YEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVG 132
Y +DA+I+FSDILV+PQA+ + VEM PG+GP P P+++ ++++ A L YV
Sbjct: 70 Y-GMDAAILFSDILVVPQAMDIEVEMKPGIGPWLPNPVRSVADVEKAVVPDAEDALGYVM 128
Query: 133 KAITLTRHKIDGKVPLIGFTGAP-------VE-------SGAQLLQVFESSADHLSREQF 178
AI LT K+ G+VPLIGF G+P V+ A+ + A H E+
Sbjct: 129 DAIRLTNEKLGGQVPLIGFAGSPWTIFCYCVQGQGSKSFDKAKAFCFSQPEAAHALLEKI 188
Query: 179 TEFSIPYLK-DIRSGVRA-------------------------KLTEKSLEQVPMTIFAK 212
T+ +I YLK + +GV A ++ + + P+ +F K
Sbjct: 189 TQTTIDYLKAKVAAGVHAVQLFDSWGGMLSPADYQEFSWQYLQRIVDALKDLAPVIVFGK 248
Query: 213 GAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTE 272
G +L+ AQ G +G+DWT+ P +AR++ G NITLQGN DP L P+ I+ + E
Sbjct: 249 GCWFALETMAQSGASALGVDWTLTPQKARELSGGNITLQGNFDPARLLSPPDTIRRMVRE 308
Query: 273 MVKKFGKHRYIANLGHGITPQTPLESMTVFTETV 306
M++ FGK +YI NLGHGI P+ P+E F + V
Sbjct: 309 MIRGFGKDKYIVNLGHGILPEVPVEHAGAFIDAV 342
>UniRef50_O18601 Cluster: Uroporphyrinogen decarboxylase; n=9;
Fungi/Metazoa group|Rep: Uroporphyrinogen decarboxylase
- Drosophila virilis (Fruit fly)
Length = 386
Score = 249 bits (610), Expect = 6e-65
Identities = 115/148 (77%), Positives = 132/148 (89%), Gaps = 1/148 (0%)
Query: 8 FPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTL 67
FP LKND LLRAA G+ VD+VPVWVMRQAGRYLPEFQE+R +HDFFTVCRTPELACEVT+
Sbjct: 18 FPPLKNDNLLRAARGEVVDRVPVWVMRQAGRYLPEFQELRKQHDFFTVCRTPELACEVTM 77
Query: 68 QPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSR 127
QPLRR++ LDASIIFSDILVIPQALG+TVEMH GVGPV P+P+ TP ++ L P+GA+SR
Sbjct: 78 QPLRRFD-LDASIIFSDILVIPQALGLTVEMHAGVGPVLPQPICTPEDLKRLTPDGALSR 136
Query: 128 LDYVGKAITLTRHKIDGKVPLIGFTGAP 155
L YVG AIT+ RHK+DG+VPLIGFTGAP
Sbjct: 137 LTYVGDAITMMRHKLDGRVPLIGFTGAP 164
Score = 193 bits (470), Expect = 6e-48
Identities = 112/224 (50%), Positives = 139/224 (62%), Gaps = 27/224 (12%)
Query: 113 PSEIDGLQPEGAVSRLDYVGKAITLTRHKIDGKVPLIGFTGAPVE-------SGAQLLQV 165
P + G EG S+ KA LT + D K+ LI T V+ +GAQ+LQV
Sbjct: 164 PWTLMGYMIEGGGSKTMSKAKA-WLTNYPEDTKLFLILLTDVIVDYLEMQVIAGAQMLQV 222
Query: 166 FESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMT----------------- 208
FESSA+HLS+E+F S PYL+ IR + +LT+K + VP+
Sbjct: 223 FESSAEHLSKEEFLLGSEPYLRRIRDDLVDRLTKKVIPAVPLVSSYPNNIFTLLTYLISL 282
Query: 209 --IFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEI 266
IFAKGAGHSL Q++LGY+ IGLDWTVDP EAR +VG NITLQGNLDPQ +Y P E+
Sbjct: 283 LIIFAKGAGHSLKEQSELGYDVIGLDWTVDPVEARAVVGPNITLQGNLDPQSMYCEPNEL 342
Query: 267 KTLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHEAI 310
++L TEMV K GK RYIAN+GHGITPQTP+ SM V E H A+
Sbjct: 343 RSLATEMVHKCGKSRYIANVGHGITPQTPITSMEVLVEAAHNAL 386
>UniRef50_Q9V595 Cluster: Uroporphyrinogen decarboxylase; n=35;
cellular organisms|Rep: Uroporphyrinogen decarboxylase -
Drosophila melanogaster (Fruit fly)
Length = 356
Score = 246 bits (603), Expect = 4e-64
Identities = 114/150 (76%), Positives = 131/150 (87%), Gaps = 1/150 (0%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
K FP LKND LLRAA G+ VD+VPVWVMRQAGRYLPEFQE+R HDFFTVCRTPELACEV
Sbjct: 5 KPFPVLKNDNLLRAARGEVVDRVPVWVMRQAGRYLPEFQELRKHHDFFTVCRTPELACEV 64
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAV 125
T+QPLRR++ LDASIIFSDILVIPQALG+TVEMH GVGPV P+P+ P ++ L P+GA+
Sbjct: 65 TMQPLRRFD-LDASIIFSDILVIPQALGLTVEMHAGVGPVLPQPIVVPEDLKRLTPDGAL 123
Query: 126 SRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
SRL YVG AIT+ RHK++G+VPLIGFTGAP
Sbjct: 124 SRLSYVGDAITMMRHKLEGRVPLIGFTGAP 153
Score = 235 bits (574), Expect = 1e-60
Identities = 116/205 (56%), Positives = 148/205 (72%), Gaps = 8/205 (3%)
Query: 113 PSEIDGLQPEGAVSRLDYVGKAITLTRHKIDGKV-------PLIGFTGAPVESGAQLLQV 165
P + G EG S+ KA L H D K+ ++ + V++GAQ+LQV
Sbjct: 153 PWTLMGYMIEGGGSKTMSKAKA-WLNEHPEDSKLFLNLLTDAIVDYLEMQVKAGAQMLQV 211
Query: 166 FESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLG 225
FESSA+HLS+EQF ++ +PYLK IR + +LT+K++ VPMT+FAKGAGHSL Q++LG
Sbjct: 212 FESSAEHLSKEQFLQWCVPYLKRIRDELVDRLTKKAIPVVPMTLFAKGAGHSLKEQSELG 271
Query: 226 YETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVKKFGKHRYIAN 285
Y+ IGLDWTVDP EAR +VG NITLQGNLDPQD+Y+ P+E++ LTTEMV KFGK RYIAN
Sbjct: 272 YDVIGLDWTVDPLEARNLVGPNITLQGNLDPQDMYRDPDELRNLTTEMVHKFGKSRYIAN 331
Query: 286 LGHGITPQTPLESMTVFTETVHEAI 310
LGHGITPQTP+ SM V E VH+A+
Sbjct: 332 LGHGITPQTPITSMEVLVEAVHKAL 356
>UniRef50_UPI00015B4317 Cluster: PREDICTED: similar to
ENSANGP00000021292; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000021292 - Nasonia
vitripennis
Length = 874
Score = 229 bits (559), Expect = 9e-59
Identities = 104/149 (69%), Positives = 125/149 (83%), Gaps = 1/149 (0%)
Query: 7 NFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVT 66
NFP L+NDR+LRAA G+ VDKVPVW+MRQAGRYLPEF+E+R KHDFF++C+TP LACE+T
Sbjct: 523 NFPPLQNDRILRAARGEPVDKVPVWIMRQAGRYLPEFRELRTKHDFFSICQTPALACEIT 582
Query: 67 LQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVS 126
LQP++R+ LDASIIFSDILVIPQA+G+ VEM PGVGPV P+PL P+ I L+
Sbjct: 583 LQPIKRFP-LDASIIFSDILVIPQAMGLVVEMRPGVGPVLPEPLADPTHISRLKMPDVDK 641
Query: 127 RLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
L YVG+AITLTRH ++GKVPLIGFTGAP
Sbjct: 642 DLGYVGEAITLTRHSLEGKVPLIGFTGAP 670
Score = 170 bits (413), Expect = 4e-41
Identities = 84/162 (51%), Positives = 109/162 (67%), Gaps = 2/162 (1%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
++ + V++GAQLLQVFES D L+ E F E+S+ Y K I V+AKL ++ +VPM
Sbjct: 711 IVDYLVMQVKAGAQLLQVFESHGDFLNTELFKEYSLKYFKQISQKVKAKLDSLNIPKVPM 770
Query: 208 TIFAKGAG-HSLDIQA-QLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEE 265
F KGA S++I A + GY+ IGLDWTVDP EAR+ VG NITLQGN+DP LY T E+
Sbjct: 771 IAFPKGATLDSIEIFAKEAGYDVIGLDWTVDPVEARQRVGPNITLQGNMDPTALYSTTEK 830
Query: 266 IKTLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVH 307
++ MV+ FGK RYIANLGHGI P P+ S+ F E +H
Sbjct: 831 VRQRAENMVRLFGKDRYIANLGHGILPDAPIPSVEAFIEGIH 872
>UniRef50_P06132 Cluster: Uroporphyrinogen decarboxylase; n=29;
Fungi/Metazoa group|Rep: Uroporphyrinogen decarboxylase
- Homo sapiens (Human)
Length = 367
Score = 198 bits (484), Expect = 1e-49
Identities = 95/151 (62%), Positives = 114/151 (75%), Gaps = 2/151 (1%)
Query: 6 KNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV 65
+ FPELKND LRAA G+ D PVW MRQAGRYLPEF+E R DFF+ CR+PE CE+
Sbjct: 9 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEL 68
Query: 66 TLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGA 124
TLQPLRR+ LDA+IIFSDILV+PQALGM V M PG GP FP+PL+ +++ L+ PE
Sbjct: 69 TLQPLRRFP-LDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVV 127
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L YV +AITLTR ++ G+VPLIGF GAP
Sbjct: 128 ASELGYVFQAITLTRQRLAGRVPLIGFAGAP 158
Score = 167 bits (406), Expect = 3e-40
Identities = 79/161 (49%), Positives = 106/161 (65%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + V +GAQ LQ+FES A HL + F +F++PY++D+ V+A+L E L VPM
Sbjct: 199 LVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 258
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
IFAK +L+ AQ GYE +GLDWTV P +AR+ VG+ +TLQGNLDP LY + EEI
Sbjct: 259 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIG 318
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
L +M+ FG HRYIANLGHG+ P E + F + VH+
Sbjct: 319 QLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 359
>UniRef50_Q9USJ5 Cluster: Uroporphyrinogen decarboxylase; n=24;
Fungi/Metazoa group|Rep: Uroporphyrinogen decarboxylase
- Schizosaccharomyces pombe (Fission yeast)
Length = 355
Score = 184 bits (447), Expect = 3e-45
Identities = 89/147 (60%), Positives = 114/147 (77%), Gaps = 2/147 (1%)
Query: 11 LKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPL 70
+KND +LRAA G+ V++ PVW+MRQAGRYLPE+ ++R K FF +C+TPE ACE+TLQP+
Sbjct: 1 MKNDLILRAAKGEEVERPPVWIMRQAGRYLPEYHKLRAKQSFFEMCQTPETACELTLQPV 60
Query: 71 RRYEH-LDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVS-RL 128
R++ LDA+IIFSDILVIPQALGM V M GP FPKPL P +ID L+ +S +L
Sbjct: 61 TRFKGLLDAAIIFSDILVIPQALGMQVVMLEQKGPHFPKPLVVPEDIDLLEKTPNISAKL 120
Query: 129 DYVGKAITLTRHKIDGKVPLIGFTGAP 155
YV AI+LTR K+DG+VPL+GF+GAP
Sbjct: 121 GYVMDAISLTREKLDGQVPLMGFSGAP 147
Score = 147 bits (357), Expect = 3e-34
Identities = 77/156 (49%), Positives = 99/156 (63%), Gaps = 3/156 (1%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
V +GAQLLQ+F+S A LS E FTE++ PYL I V+ L +K ++VPM +FAKGA
Sbjct: 196 VYAGAQLLQIFDSWAGELSPEDFTEYAYPYLVRICQEVKQHLKKKKRDEVPMIVFAKGAW 255
Query: 216 HSLDIQAQLGYETIGLDWTVDPTEARKIVG-ENITLQGNLDPQDLYKTPEEIKTLTTEMV 274
+++D GY+ IGLDWTV P EA +I G +T QGNLDP LY T E I+ T EM+
Sbjct: 256 YAIDQLCDSGYDVIGLDWTVSPKEAVRIRGNRRVTFQGNLDPNILYGTREIIEARTKEMI 315
Query: 275 KKF--GKHRYIANLGHGITPQTPLESMTVFTETVHE 308
+ F GK YI NLGHGITP + + F E H+
Sbjct: 316 QDFGGGKQGYIINLGHGITPGVNPDDVRFFLEKCHQ 351
>UniRef50_P32347 Cluster: Uroporphyrinogen decarboxylase; n=4;
Fungi/Metazoa group|Rep: Uroporphyrinogen decarboxylase
- Saccharomyces cerevisiae (Baker's yeast)
Length = 362
Score = 179 bits (436), Expect = 7e-44
Identities = 86/152 (56%), Positives = 109/152 (71%), Gaps = 3/152 (1%)
Query: 7 NFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVT 66
NFP KND +LRAA G+ V++ P W+MRQAGRYLPE+ EV+ DFF CR E+A E+T
Sbjct: 3 NFPAPKNDLILRAAKGEKVERPPCWIMRQAGRYLPEYHEVKNNRDFFQTCRDAEIASEIT 62
Query: 67 LQPLRRYEHL-DASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGL--QPEG 123
+QP+RRY L DA+IIFSDILVIPQA+GM VEM G GP FP+PL+ P ++ +
Sbjct: 63 IQPVRRYRGLIDAAIIFSDILVIPQAMGMRVEMLEGKGPHFPEPLRNPEDLQTVLDYKVD 122
Query: 124 AVSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
+ LD+ KAIT+TR K+DG+VPL GF G P
Sbjct: 123 VLKELDWAFKAITMTRIKLDGEVPLFGFCGGP 154
Score = 132 bits (319), Expect = 1e-29
Identities = 73/173 (42%), Positives = 99/173 (57%), Gaps = 5/173 (2%)
Query: 140 HKIDGKVP--LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKL 197
HK+ K+ + F V +GAQ+LQVFES LS F EFS+PYL+ I V +L
Sbjct: 185 HKLLQKITDVAVEFLSQQVVAGAQILQVFESWGGELSSVDFDEFSLPYLRQIAERVPKRL 244
Query: 198 TEKSL-EQVPMTIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDP 256
E + EQ+PM +FAKG+ ++LD G++ + LDW+ DP EA KI +TLQGNLDP
Sbjct: 245 QELGIMEQIPMIVFAKGSWYALDKLCCSGFDVVSLDWSWDPREAVKINKNRVTLQGNLDP 304
Query: 257 QDLYKTPEEIKTLTTEMVKKF--GKHRYIANLGHGITPQTPLESMTVFTETVH 307
+Y + E I +M++ F GK RYI N GHG P + + F E H
Sbjct: 305 GVMYGSKEVITKKVKQMIEAFGGGKSRYIVNFGHGTHPFMDPDVIKFFLEECH 357
>UniRef50_Q83EP0 Cluster: Uroporphyrinogen decarboxylase; n=4;
Coxiella burnetii|Rep: Uroporphyrinogen decarboxylase -
Coxiella burnetii
Length = 361
Score = 162 bits (394), Expect = 9e-39
Identities = 78/146 (53%), Positives = 104/146 (71%), Gaps = 2/146 (1%)
Query: 11 LKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVK-HDFFTVCRTPELACEVTLQP 69
LKNDR +RA L + VD+ PVW+MRQAGRYLPE++++R K +F C+TPELACE TLQP
Sbjct: 4 LKNDRFIRALLRQPVDRTPVWIMRQAGRYLPEYRQLREKVPNFMAFCKTPELACEATLQP 63
Query: 70 LRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLD 129
LRR+ LDA+IIFSDIL IP A+G+ + + P VGPV P+++ +++ LQ L
Sbjct: 64 LRRFP-LDAAIIFSDILTIPDAMGVDLHIAPTVGPVIRNPVRSAQDVNRLQMPAVEEALS 122
Query: 130 YVGKAITLTRHKIDGKVPLIGFTGAP 155
Y+ AI LT +D +VPLIGF G+P
Sbjct: 123 YLFDAIRLTVKALDHRVPLIGFAGSP 148
Score = 117 bits (282), Expect = 3e-25
Identities = 56/159 (35%), Positives = 93/159 (58%), Gaps = 4/159 (2%)
Query: 149 IGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMT 208
I + A +++GA ++ +F++ L+ + +FS+ YL I + V + +K+ ++P+
Sbjct: 190 IAYLNAQIKAGADVVMLFDTWGGLLTPSLYRQFSLDYLSQIAAEV---VRQKNGRKIPLI 246
Query: 209 IFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKT 268
F K G L+ A G + +GLDWT D +AR+ VG+ + LQGNLDP L PE I T
Sbjct: 247 FFTKNGGQWLESIANSGCDAVGLDWTTDIGQARRRVGDRVALQGNLDPAILLSNPESIST 306
Query: 269 LTTEMVKKFGK-HRYIANLGHGITPQTPLESMTVFTETV 306
+++K +G+ ++ NLGHGI P TP+E++ E V
Sbjct: 307 AAVDILKSYGQGSGHVFNLGHGIDPSTPIENVAALVEAV 345
>UniRef50_Q23DD3 Cluster: Uroporphyrinogen decarboxylase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Uroporphyrinogen decarboxylase family protein -
Tetrahymena thermophila SB210
Length = 398
Score = 155 bits (375), Expect = 2e-36
Identities = 80/151 (52%), Positives = 100/151 (66%), Gaps = 2/151 (1%)
Query: 5 NKNFPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACE 64
++ FP +KND LLR + +D +P+WVMRQAGRYLPEF+EVR FF +C P LA E
Sbjct: 47 DQKFPVMKNDTLLRVIKREKIDHLPIWVMRQAGRYLPEFREVRKIWSFFELCDNPLLAAE 106
Query: 65 VTLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGA 124
VTLQPL R+ +DA IIFSDILV+P+ +GM V M GPVFP+PL PS++ L
Sbjct: 107 VTLQPLERFP-MDAGIIFSDILVVPKVMGMEVIMEEKRGPVFPQPLVEPSDLQKLSIPDP 165
Query: 125 VSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L V A+ L R ++GKV IGF GAP
Sbjct: 166 ES-LGDVYDALYLFRQAVEGKVTTIGFAGAP 195
Score = 94.7 bits (225), Expect = 3e-18
Identities = 55/162 (33%), Positives = 87/162 (53%), Gaps = 7/162 (4%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
LI + +E GAQ++Q+F+S A L E + EF + Y + + V+ + E P+
Sbjct: 236 LIEYISKQIEGGAQIIQLFDSWAGELGHEDYWEFGLSYCVRVATEVKKRHPE-----TPI 290
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGE-NITLQGNLDPQDLYKTPEEI 266
+FAKG HS + ++ +G+D+ D + A K + N +QGNLDP L + I
Sbjct: 291 IMFAKG-NHSDMVFKHDCFDCVGIDYAWDLSLAAKYSQQYNKVIQGNLDPGVLLAEKDTI 349
Query: 267 KTLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
+ T +M+ G RYI NLGHG+ P+ LE + VF + H+
Sbjct: 350 REKTRKMIDIVGVDRYIVNLGHGMWPEHDLEHLAVFVDETHK 391
>UniRef50_A0Q8F6 Cluster: Uroporphyrinogen decarboxylase; n=11;
Francisella tularensis|Rep: Uroporphyrinogen
decarboxylase - Francisella tularensis subsp. novicida
(strain U112)
Length = 344
Score = 147 bits (356), Expect = 4e-34
Identities = 75/153 (49%), Positives = 104/153 (67%), Gaps = 6/153 (3%)
Query: 15 RLLRAALG-KSVDKVPVWVMRQAGRYLPEFQEVRVKHD-FFTVCRTPELACEVTLQPLRR 72
+L A G K +DK PVW+MRQAGRYLPE++ VR K D F +CR + CEV L PL+R
Sbjct: 3 KLFLDAFGEKKLDKPPVWIMRQAGRYLPEYRAVRAKFDNFMDMCRNADACCEVALHPLQR 62
Query: 73 YEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQP-EGAVSRLDYV 131
Y+ LDA+I+FSDIL IP+A+GM ++ G GPVF +P+Q+ ++D L+ E ++ LDYV
Sbjct: 63 YD-LDAAIVFSDILTIPEAMGMDLKFIKGTGPVFSEPIQSQKDLDKLKSIEDSIGSLDYV 121
Query: 132 GKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQ 164
A+ T I+ VPLIGFTG+P A +++
Sbjct: 122 YNAVKTTSSTIN--VPLIGFTGSPWTLAAYMIE 152
Score = 81.8 bits (193), Expect = 2e-14
Identities = 45/156 (28%), Positives = 77/156 (49%), Gaps = 9/156 (5%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
V++GA + +F++ L E + FS+ Y++ I V+ K+ +P+ F KG
Sbjct: 192 VKAGASCVMIFDTWGGILPLEHYKNFSLKYMEYIAKNVKQKIN------IPIVFFTKGGS 245
Query: 216 HSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK---TLTTE 272
+ + + +G+DW+V +AR +G LQGN DP LY + + I+ E
Sbjct: 246 NFFEEIKDKSCDGVGVDWSVTLKQARHRIGVGKVLQGNFDPAFLYGSKQSIRETVRANIE 305
Query: 273 MVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
++ + YI NLGHGI P +S+ V + + E
Sbjct: 306 FIQSDKLNNYIVNLGHGIYPDIDPDSVRVMIDAIRE 341
>UniRef50_A3HYD0 Cluster: Uroporphyrinogen decarboxylase; n=1;
Algoriphagus sp. PR1|Rep: Uroporphyrinogen decarboxylase
- Algoriphagus sp. PR1
Length = 340
Score = 146 bits (355), Expect = 5e-34
Identities = 78/168 (46%), Positives = 111/168 (66%), Gaps = 2/168 (1%)
Query: 10 ELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVK-HDFFTVCRTPELACEVTLQ 68
EL+ND LLRAA G+ ++ PVW+MRQAGR LPE++ VR F + +TPELA EVT+Q
Sbjct: 2 ELQNDLLLRAAKGEKTERTPVWLMRQAGRILPEYRAVRESVSGFIELAQTPELAAEVTIQ 61
Query: 69 PLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRL 128
P+ +DA+IIFSDILVIP+A+G+ EM GP FP+ ++T +++ L+ + L
Sbjct: 62 PVDLLG-VDAAIIFSDILVIPEAMGLPYEMIEKKGPWFPETVRTEADLKKLRVADGANDL 120
Query: 129 DYVGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQVFESSADHLSRE 176
YV KAI +T+ ++G+VPLIGF GAP A +++ S +RE
Sbjct: 121 SYVIKAIEITKKNLNGRVPLIGFAGAPWTIFAYMVEGSGSKTFSRARE 168
Score = 132 bits (319), Expect = 1e-29
Identities = 69/158 (43%), Positives = 98/158 (62%), Gaps = 9/158 (5%)
Query: 149 IGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMT 208
I + A +++GA L+QVF+S A L +Q+ EFS Y+ I + +VP+T
Sbjct: 189 INYLKAQIKAGADLVQVFDSWAGILGPKQYLEFSHRYISQICDAIN---------EVPVT 239
Query: 209 IFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKT 268
+FAKGA + + +L ETIGLDW + E+ K++G N TLQGNLDP LY PEE+++
Sbjct: 240 VFAKGAFFAREEMGKLNCETIGLDWNMGIEESYKLIGANKTLQGNLDPAALYGNPEEVRS 299
Query: 269 LTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETV 306
T EM+++F R+IANLGHG+ P E + VF ETV
Sbjct: 300 ATLEMMEQFKGKRHIANLGHGVYPDIKPEKVKVFIETV 337
>UniRef50_A7H9E0 Cluster: Uroporphyrinogen decarboxylase; n=2;
Anaeromyxobacter|Rep: Uroporphyrinogen decarboxylase -
Anaeromyxobacter sp. Fw109-5
Length = 350
Score = 146 bits (354), Expect = 6e-34
Identities = 107/340 (31%), Positives = 163/340 (47%), Gaps = 49/340 (14%)
Query: 15 RLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRYE 74
R L A + VD++PVW+MRQAGRY P ++ VR F +CR+PEL +VT+ P+ +
Sbjct: 8 RFLEACRKQPVDRLPVWMMRQAGRYQPSYRAVRANVGFLELCRSPELIAQVTVAPIDEF- 66
Query: 75 HLDASIIFSDILVIPQALGMTVEMHPGV------GPVFPKPLQTPSEIDGLQPEGAVSRL 128
DA+I+FSDILV A+G+ + G GP P++T +++D L+ L
Sbjct: 67 GFDAAILFSDILVHLPAMGLDLSFEKGEKGKGDGGPKIANPVRTRADVDALKVPAPKKDL 126
Query: 129 DYVGKAITLTRHKIDGKVPLIGFTGAP-------VESGAQ------LLQVFESSADHLSR 175
YV + R + +VPLIGF G P VE G+Q + E H
Sbjct: 127 PYVLDGVRAIRAALRDRVPLIGFVGGPFTVASYAVEGGSQGFTRLKTMLYAEPRTAHALF 186
Query: 176 EQFTEFSIPYLKD-IRSGVRA---------KLTEKSLEQ-----------------VPMT 208
E+ T+ +I +++ I +G +A +L LE+ VP
Sbjct: 187 EKLTQAAIVQIEEQIAAGAQAAQIFESWLGELDRADLEEFAFPYLARIAEAVKRTGVPSI 246
Query: 209 IFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKT 268
F+ G L+ ++LGY+ + +DW + EAR+ + +QGN+D L E
Sbjct: 247 FFSTGTTAHLEPISKLGYDVVSVDWRIPIDEARR-RAPGVAIQGNMDSTVLLGPKEVAVE 305
Query: 269 LTTEMVKKFGKH-RYIANLGHGITPQTPLESMTVFTETVH 307
+V+ G+ YI NLGHGI P TP E++ + VH
Sbjct: 306 RALSIVRAAGREPGYIFNLGHGIQPGTPTETVKAVVDAVH 345
>UniRef50_A3ERP3 Cluster: Uroporphyrinogen decarboxylase; n=1;
Leptospirillum sp. Group II UBA|Rep: Uroporphyrinogen
decarboxylase - Leptospirillum sp. Group II UBA
Length = 356
Score = 146 bits (353), Expect = 8e-34
Identities = 74/176 (42%), Positives = 110/176 (62%), Gaps = 3/176 (1%)
Query: 9 PELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQ 68
P LKND LRA G+ ++ PVW+MRQAGRY+PE+QE+R K F +C+TP+LA + T+
Sbjct: 3 PALKNDLFLRACRGEKTERPPVWIMRQAGRYMPEYQEIRKKTSFLGLCKTPDLAAQATML 62
Query: 69 PLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRL 128
P+ +DA+I+FSDIL+ +A+GM +E GP FP+P+Q+ ++D L V+
Sbjct: 63 PVDML-GVDAAILFSDILIPVEAMGMELEFSEHKGPSFPRPVQSRMDVDRLLVPEPVAHT 121
Query: 129 DYVGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIP 184
+V +AI ++ G++PLIGF GAP +++ E S D SR + FS P
Sbjct: 122 GFVAEAIREINRRLSGRLPLIGFAGAPFTLATYMVE-GEISKD-FSRVKQMMFSDP 175
Score = 79.0 bits (186), Expect = 1e-13
Identities = 42/164 (25%), Positives = 79/164 (48%), Gaps = 8/164 (4%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
+I + +E+G Q+F++ A LS + F++PY++ I ++ +P
Sbjct: 189 VIRYLEMQIEAGIHAYQIFDTWAGSLSPVHYRSFALPYVRRIVDSLQR-------HGIPS 241
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
++ G+ L+ G + +DW + R+ V ++++QGNLDP L TP ++
Sbjct: 242 ILYVNGSCALLEDMVTAGTNVVSVDWRMSLANVRERVPASVSIQGNLDPVSLLGTPAILR 301
Query: 268 TLTTEMVKKF-GKHRYIANLGHGITPQTPLESMTVFTETVHEAI 310
T +++ G+ Y+ NLGHGI P TP+ V + +
Sbjct: 302 DETRRILEDMKGRPGYVFNLGHGILPSTPVSMAKYLVSLVQKGL 345
>UniRef50_Q8KAW2 Cluster: Uroporphyrinogen decarboxylase; n=11;
Bacteroidetes/Chlorobi group|Rep: Uroporphyrinogen
decarboxylase - Chlorobium tepidum
Length = 351
Score = 143 bits (347), Expect = 4e-33
Identities = 71/144 (49%), Positives = 100/144 (69%), Gaps = 1/144 (0%)
Query: 11 LKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPL 70
LKND +RA ++ + P+WVMRQAGRYLPE++ VR K DF T+C+TPELACEVT+QP+
Sbjct: 2 LKNDLFIRALKRQATPRTPIWVMRQAGRYLPEYRAVREKTDFLTLCKTPELACEVTIQPV 61
Query: 71 RRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDY 130
+DA+IIFSDILV+ +A+GM VE+ G P+++ ++ID L +L Y
Sbjct: 62 -DLMGVDAAIIFSDILVVNEAMGMNVEIIETKGIKLTPPIRSQADIDKLIDPDIDEKLGY 120
Query: 131 VGKAITLTRHKIDGKVPLIGFTGA 154
V AI L + +++ +VPLIGF+GA
Sbjct: 121 VLDAIRLAKKELNDRVPLIGFSGA 144
Score = 114 bits (275), Expect = 2e-24
Identities = 59/157 (37%), Positives = 91/157 (57%), Gaps = 9/157 (5%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
VE+GA +Q+F+S A LS + + EF++PY+K + V+A E +P+ FAK
Sbjct: 194 VEAGADAIQIFDSWASALSEDDYREFALPYIKQNVAAVKAAYPE-----IPVIAFAKDMN 248
Query: 216 HSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVK 275
L A G + +GL W +D +ARK + + + LQGN+DP LY TPE+IK+ +++K
Sbjct: 249 TILSDIADCGADAVGLGWNIDIAKARKELNDRVCLQGNMDPTVLYGTPEKIKSEAAKVLK 308
Query: 276 KFGKHR----YIANLGHGITPQTPLESMTVFTETVHE 308
+FG+H ++ NLGHGI P ++ E V E
Sbjct: 309 QFGQHNDHSGHVFNLGHGILPDVDPANLKCLVEFVKE 345
>UniRef50_A0C9P3 Cluster: Uroporphyrinogen decarboxylase; n=3;
Paramecium tetraurelia|Rep: Uroporphyrinogen
decarboxylase - Paramecium tetraurelia
Length = 398
Score = 142 bits (345), Expect = 8e-33
Identities = 71/153 (46%), Positives = 100/153 (65%), Gaps = 3/153 (1%)
Query: 4 SNKNFPELKNDRLLRAALG-KSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELA 62
+N+ FP N RLL A D+ P+W+MRQAGRYLPEF+E+ DFF C+ P +A
Sbjct: 30 TNQTFPRQTNTRLLDAFQSFAQFDRAPIWMMRQAGRYLPEFKEIMKNRDFFDACQDPFIA 89
Query: 63 CEVTLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPE 122
E+TLQPL+++E +DA+IIFSDIL +P+A+GM + M GP+ L+T +I+ ++
Sbjct: 90 AEITLQPLKQFE-IDAAIIFSDILTLPKAMGMEIVMDKEKGPIIKNKLETVDDINRIKSP 148
Query: 123 GAVSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
S L++V A+ LTR + GK LIGF GAP
Sbjct: 149 DPES-LEHVYDALYLTRQALQGKQTLIGFCGAP 180
Score = 70.5 bits (165), Expect = 5e-11
Identities = 52/157 (33%), Positives = 77/157 (49%), Gaps = 14/157 (8%)
Query: 157 ESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGH 216
E GAQ++Q+F+S A + + EF IP L+ + G + + P+ +FAK
Sbjct: 231 EGGAQVIQIFDSFAGQIPPIDYIEFVIPSLRILLEGFK-----QECPNTPLIMFAKDQNG 285
Query: 217 SLDIQAQLGY---ET-----IGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKT 268
I A L ET LD V KI+ + T+QGNL+P LY T + IK
Sbjct: 286 VEVILAFLKMCLGETPLIDGFQLDSNVSDDVLIKIIESDRTIQGNLEPGVLYGTQQIIKK 345
Query: 269 LTTEMVKKF-GKHRYIANLGHGITPQTPLESMTVFTE 304
++M++K RYI NL HG+TP +E + F +
Sbjct: 346 RVSQMIEKLQTTRRYIMNLSHGLTPDHEVEKVRQFIQ 382
>UniRef50_Q8CWI5 Cluster: Uroporphyrinogen decarboxylase; n=1;
Wigglesworthia glossinidia endosymbiont of Glossina
brevipalpis|Rep: Uroporphyrinogen decarboxylase -
Wigglesworthia glossinidia brevipalpis
Length = 360
Score = 136 bits (328), Expect = 9e-31
Identities = 62/145 (42%), Positives = 99/145 (68%), Gaps = 2/145 (1%)
Query: 12 KNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVK-HDFFTVCRTPELACEVTLQPL 70
+ND LR+AL KSV + P+W+MRQ+GRYL E+Q ++ + DF ++C+TP+L+ + L P+
Sbjct: 5 ENDSYLRSALRKSVKRTPIWIMRQSGRYLKEYQSIKKQAKDFLSLCKTPDLSSKAALIPI 64
Query: 71 RRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDY 130
+++ LDA+IIFSDIL++P A+GM V + +GP F P+ + S++ L L Y
Sbjct: 65 KKFS-LDAAIIFSDILILPYAMGMDVNFYENLGPSFLNPISSISDMKNLNVPDPEKNLKY 123
Query: 131 VGKAITLTRHKIDGKVPLIGFTGAP 155
V +I + ++D K+PLIGF+G+P
Sbjct: 124 VLDSIKIICKELDKKIPLIGFSGSP 148
Score = 95.1 bits (226), Expect = 2e-18
Identities = 53/161 (32%), Positives = 89/161 (55%), Gaps = 4/161 (2%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
+I + + + G + +F++ L+ E++ E+S+ Y+ I + K ++P+
Sbjct: 189 IILYLNSQIIYGVNAIIIFDTWGGILTEEKYCEYSLHYMSLIIKNLFCKYKGN---KIPV 245
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
TIF K G + A+ G + I LDW+VD ARK V I +QGN+DP +LY + I+
Sbjct: 246 TIFTKNGGQWIKKIAKSGCDVIALDWSVDIEYARKQVNGKIAIQGNMDPFELYGSFSSIE 305
Query: 268 TLTTEMVKKFGKHR-YIANLGHGITPQTPLESMTVFTETVH 307
T +++ KFG + +I +LGHGI TP E++ E+VH
Sbjct: 306 EETNKILSKFGYNSGHIFSLGHGIYKDTPPENVNFLIESVH 346
>UniRef50_A6EES3 Cluster: Uroporphyrinogen decarboxylase; n=1;
Pedobacter sp. BAL39|Rep: Uroporphyrinogen decarboxylase
- Pedobacter sp. BAL39
Length = 340
Score = 134 bits (324), Expect = 3e-30
Identities = 61/143 (42%), Positives = 95/143 (66%), Gaps = 2/143 (1%)
Query: 13 NDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRR 72
N L AA K ++ PVW+MRQAGR++PE+ E++ K+ F +C+TPE+A +VT+ P+
Sbjct: 2 NTLFLDAAFSKQTERPPVWMMRQAGRFMPEYWEIKNKYSFLEMCKTPEIAADVTMLPVDL 61
Query: 73 YEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVG 132
+DA+I+FSDILV +A+G + GVGP F P++T ++D L + + +L YV
Sbjct: 62 L-GIDAAILFSDILVTGEAMGGDLSFTQGVGPKFANPVRTEKDVDNLNVD-VLDKLQYVA 119
Query: 133 KAITLTRHKIDGKVPLIGFTGAP 155
AI + + +++G +PLIGF GAP
Sbjct: 120 DAIKVIQQRLNGSIPLIGFAGAP 142
Score = 82.6 bits (195), Expect = 1e-14
Identities = 48/172 (27%), Positives = 84/172 (48%), Gaps = 10/172 (5%)
Query: 140 HKIDGKVPLI--GFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKL 197
H++ K+ + + + +G +Q+F+S A LS + EFS Y+++I + + K
Sbjct: 173 HRLLAKIAKVTADYLNLQIAAGVNAIQIFDSWALALSWNDYQEFSHRYIQEIIANLNRK- 231
Query: 198 TEKSLEQVPMTIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQ 257
+P+ F KG+ I A+ + I +DW D +K + I +QGNLDP
Sbjct: 232 ------DIPVISFCKGSSVFAPIMAEANPDVISVDWNADLLNIKKSLPAGIAVQGNLDPH 285
Query: 258 DLYKTPEEIKTLTTEMVKKF-GKHRYIANLGHGITPQTPLESMTVFTETVHE 308
LY IK ++ ++ G++ +I NLGHGI P P + + E + +
Sbjct: 286 ILYADKPVIKKHILQLFERMRGENGFIFNLGHGIMPDIPFDHVKYAIEVIKD 337
>UniRef50_Q6ANR5 Cluster: Uroporphyrinogen decarboxylase; n=6;
Deltaproteobacteria|Rep: Uroporphyrinogen decarboxylase
- Desulfotalea psychrophila
Length = 339
Score = 132 bits (320), Expect = 8e-30
Identities = 65/152 (42%), Positives = 95/152 (62%), Gaps = 3/152 (1%)
Query: 13 NDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRR 72
ND L+A G+ D P+W+MRQAGRYLP +Q++R K F +C+ P L EVTLQP+
Sbjct: 2 NDTFLKACRGEKTDYTPIWMMRQAGRYLPAYQKIRGKVSFLELCKNPALCVEVTLQPVDL 61
Query: 73 YEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVG 132
+DA+I+FSDIL++ +A+G +E + G GPVFP P++ + +D L A +V
Sbjct: 62 L-GMDAAILFSDILILMEAMGAKLEFNEGCGPVFPNPIKDQTALDALIIPDADDATGFVM 120
Query: 133 KAITLTRHKIDGKVPLIGFTGAPVESGAQLLQ 164
+ I L R ++ +VPLIGF GAP L++
Sbjct: 121 ETIRLLRGEL--QVPLIGFAGAPFTCATYLIE 150
Score = 77.4 bits (182), Expect = 4e-13
Identities = 63/194 (32%), Positives = 95/194 (48%), Gaps = 15/194 (7%)
Query: 122 EGAVSRLDYVGKAITLTR----HKIDGKVP--LIGFTGAPVESGAQLLQVFESSADHLSR 175
EG S++ + K + T+ H I K+ I + A +GAQ LQ+F+S A L+
Sbjct: 150 EGGSSKVFWETKKMMFTQPELFHGIMEKITQATILYLQAQARAGAQALQIFDSWAGVLAP 209
Query: 176 EQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLGYETIGLDWTV 235
F F++PY++ I A L + L P+ FA L++ A G +GLDW +
Sbjct: 210 CDFEVFALPYVRRI----IASLQQFDL---PIIYFANNGSTLLEMSASSGASVLGLDWRI 262
Query: 236 DPTEARKIVGENITLQGNLDPQDLYKTPEEI-KTLTTEMVKKFGKHRYIANLGHGITPQT 294
+ +A K V I LQGN+DP L +++ K + T + +I NLGHGI T
Sbjct: 263 NIGDAGKRV-PGIALQGNIDPFALLLPKDKLRKRIGTILEDAKEVKGHIFNLGHGIHQFT 321
Query: 295 PLESMTVFTETVHE 308
P E + + VHE
Sbjct: 322 PPEQARIAVDAVHE 335
>UniRef50_Q1ENA9 Cluster: Uroporphyrinogen decarboxylase precursor;
n=1; Guillardia theta|Rep: Uroporphyrinogen
decarboxylase precursor - Guillardia theta (Cryptomonas
phi)
Length = 261
Score = 132 bits (319), Expect = 1e-29
Identities = 67/150 (44%), Positives = 99/150 (66%), Gaps = 5/150 (3%)
Query: 10 ELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKH--DFFTVCRTPELACEVTL 67
+L+ND ++R A G+ +K PVW+ RQAGR+LPE++ + + +F + P+ E T+
Sbjct: 76 KLRNDLMVRVARGEKAEKTPVWLFRQAGRHLPEYEAYKKETGCNFLQLLDDPKHVAECTM 135
Query: 68 QPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEG--AV 125
QP+RRY +LDA+I+FSDILV+ +ALG+ VEM G G P PL +PSE+ P
Sbjct: 136 QPIRRY-NLDAAILFSDILVVAEALGIKVEMPGGKGITVPHPLASPSEVSTRIPASIDVK 194
Query: 126 SRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
+L +V A+ L + ++DGKVPLIGF+ AP
Sbjct: 195 DKLSHVIDAVKLIKKELDGKVPLIGFSAAP 224
>UniRef50_A5K1S0 Cluster: Uroporphyrinogen decarboxylase, putative;
n=5; Plasmodium|Rep: Uroporphyrinogen decarboxylase,
putative - Plasmodium vivax
Length = 422
Score = 132 bits (318), Expect = 1e-29
Identities = 65/156 (41%), Positives = 100/156 (64%), Gaps = 7/156 (4%)
Query: 6 KNFPELKNDRLLRA----ALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPEL 61
K F +ND +LR A G++++++PVW MRQAGRYLPE++++R KHDFF +C+ L
Sbjct: 58 KAFGRPRNDLVLRVIENKAEGRALERIPVWFMRQAGRYLPEYRQMRSKHDFFEMCQDANL 117
Query: 62 ACEVTLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEID--GL 119
+ EVT+ PL+R+ D ++FSDIL++ A+G+++ VGP F + + + E L
Sbjct: 118 SSEVTIMPLKRFP-CDMLVVFSDILIVFVAMGISITFIESVGPTFDQRVTSFEEFQRVSL 176
Query: 120 QPEGAVSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
E + L YV AI LT+ KI+ VP++GF G+P
Sbjct: 177 PLEEVIKNLHYVYDAINLTKQKINNAVPILGFAGSP 212
Score = 58.4 bits (135), Expect = 2e-07
Identities = 45/172 (26%), Positives = 86/172 (50%), Gaps = 9/172 (5%)
Query: 140 HKIDGKVP--LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKL 197
HKI GK+ + ++SGA ++Q+F+S+AD + F FS+ Y+K + + V+
Sbjct: 242 HKILGKLSDVCVSHLVNQIDSGANVVQLFDSNADVIDTHLFAHFSLFYIKRVVNTVKKLR 301
Query: 198 TEKSLEQVPMTIFAKGAGH-SLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDP 256
+ F H +D+ + + ++ + ++ + + I LQG LDP
Sbjct: 302 PHAFIILFLKENFHPDVKHLHIDVLS-ITHKQLAMN---SSSFFYNLFDGKIILQGALDP 357
Query: 257 QDLYKTPEEIKTL-TTEMVKKFGK-HRYIANLGHGITPQTPLESMTVFTETV 306
+ EE+ + T++M+ + ++YIANLGHG+ P + +E++ F V
Sbjct: 358 HIMLLQDEELVSQHTSQMINQIRHTNKYIANLGHGMLPGSRVENVRAFIRAV 409
>UniRef50_A6QAQ4 Cluster: Uroporphyrinogen decarboxylase; n=4;
Epsilonproteobacteria|Rep: Uroporphyrinogen
decarboxylase - Sulfurovum sp. (strain NBC37-1)
Length = 346
Score = 127 bits (307), Expect = 3e-28
Identities = 67/139 (48%), Positives = 88/139 (63%), Gaps = 3/139 (2%)
Query: 19 AALGKSVDKVPVWVMRQAGRYLPEFQEVRVKH-DFFTVCRTPELACEVTLQPLRRYEHLD 77
A LGK PVW+MRQAGRYLPE+ +VR + +F +C PE ACEVTLQP+ +D
Sbjct: 8 ACLGKETPYTPVWMMRQAGRYLPEYMKVRAEAGNFLNLCHDPEKACEVTLQPVD-IVGVD 66
Query: 78 ASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGL-QPEGAVSRLDYVGKAIT 136
A+I+FSDILVIP +GM + G GP F P++T +++D L E A +L YV I
Sbjct: 67 AAILFSDILVIPDEMGMDLSFVKGEGPKFSDPIKTQADVDRLIGGEEAAGKLTYVYDTIK 126
Query: 137 LTRHKIDGKVPLIGFTGAP 155
L + ++ LIGFTGAP
Sbjct: 127 LIKERLAEDKALIGFTGAP 145
Score = 81.0 bits (191), Expect = 4e-14
Identities = 47/154 (30%), Positives = 81/154 (52%), Gaps = 9/154 (5%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
+E+G ++Q+F+S A + ++ EFS Y+ +I +++K + P+ +F KG
Sbjct: 194 IEAGIDVVQIFDSWASAIEPGKYDEFSWKYMVEIADYLKSKYPD-----TPIIMFPKGIP 248
Query: 216 HSLDIQAQLG-YETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMV 274
++ G ++ G+DW A++ +G+ LQGN++P LY +E T E +
Sbjct: 249 AFIERGLVYGNFDVFGVDWGTPMALAKEKLGDQYVLQGNMEPCRLYS--KEATTECVEAI 306
Query: 275 KK-FGKHRYIANLGHGITPQTPLESMTVFTETVH 307
+K G R+I NLGHGI P P+E+ F H
Sbjct: 307 QKVMGGKRHIFNLGHGILPDVPVENAKHFVNECH 340
>UniRef50_A0GXY8 Cluster: Uroporphyrinogen decarboxylase; n=2;
Chloroflexus|Rep: Uroporphyrinogen decarboxylase -
Chloroflexus aggregans DSM 9485
Length = 356
Score = 126 bits (305), Expect = 5e-28
Identities = 61/142 (42%), Positives = 93/142 (65%), Gaps = 2/142 (1%)
Query: 14 DRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRY 73
DR LRA + VD+ P+W+MRQAGRY+PE++ VR ++ F + +TPE+A EVTLQP+ +
Sbjct: 3 DRFLRACRRQPVDRTPIWLMRQAGRYMPEYRAVRERYGFLQMVKTPEIAAEVTLQPIAAF 62
Query: 74 EHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGK 133
+DA+IIF+DIL + LG+ + G GPV P++ P ++ L P + Y
Sbjct: 63 -GVDAAIIFADILPPLEGLGLRLTYEKGEGPVIHNPIRHPHDVATLHPCDPRETVAYTLD 121
Query: 134 AITLTRHKIDGKVPLIGFTGAP 155
A+ L + +++G +PLIGF+GAP
Sbjct: 122 AVRLVKRELNG-LPLIGFSGAP 142
Score = 82.2 bits (194), Expect = 2e-14
Identities = 49/154 (31%), Positives = 81/154 (52%), Gaps = 4/154 (2%)
Query: 154 APVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKG 213
A VE+GA +Q+F+S A L+ + + + + +++ + VRA+L + P+ F
Sbjct: 189 AQVEAGADAVQIFDSWAGTLAPADYRAYVLRHTQNVVATVRARLGAAA---PPIIYFGTD 245
Query: 214 AGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEM 273
QLG + +G+DW +D A G +QGNLDP L+ PE I + E+
Sbjct: 246 MAGLAGELRQLGTDVLGVDWRIDLDVAWAQYGYEHAVQGNLDPMTLFAPPELIASRAREI 305
Query: 274 VKKF-GKHRYIANLGHGITPQTPLESMTVFTETV 306
+++ G+ +I NLGHGI +TP+E + E V
Sbjct: 306 LQRAGGRPGHIFNLGHGILTETPVEHVRYLVEFV 339
>UniRef50_Q89SK1 Cluster: Uroporphyrinogen decarboxylase; n=23;
Proteobacteria|Rep: Uroporphyrinogen decarboxylase -
Bradyrhizobium japonicum
Length = 344
Score = 126 bits (304), Expect = 7e-28
Identities = 67/128 (52%), Positives = 84/128 (65%), Gaps = 3/128 (2%)
Query: 29 PVWVMRQAGRYLPEFQEVRVK-HDFFTVCRTPELACEVTLQPLRRYEHLDASIIFSDILV 87
P+W+MRQAGRYLPE++EVR K F +C PELA EVTLQP+RR+ DA+IIFSDILV
Sbjct: 22 PMWMMRQAGRYLPEYREVRAKAGGFLDLCFNPELAAEVTLQPIRRF-GFDAAIIFSDILV 80
Query: 88 IPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAITLTRHKIDGKVP 147
IP ALG +V G GP +PL P+++ L P +L V A+ + R +D K
Sbjct: 81 IPYALGRSVRFEVGEGPRL-EPLDDPAKVATLAPRADFGKLAPVFDALKIVRGALDPKTA 139
Query: 148 LIGFTGAP 155
LIGF GAP
Sbjct: 140 LIGFCGAP 147
Score = 82.6 bits (195), Expect = 1e-14
Identities = 47/144 (32%), Positives = 74/144 (51%), Gaps = 6/144 (4%)
Query: 154 APVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKG 213
A + +GA LQ+F++ A L +F +S+ + I GVRAK+ + + P +G
Sbjct: 194 AQLAAGANALQIFDTWAGVLPPAEFARWSVEPTRRIVEGVRAKVPDAKIIGFP-----RG 248
Query: 214 AGHSLDIQAQL-GYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTE 272
AG L + G + +DWT +P R+ V + +QGNLDP L +
Sbjct: 249 AGAQLPGYVEATGVNGVSIDWTAEPAFIRERVQSRVAVQGNLDPLVLITGGAALDRAVDN 308
Query: 273 MVKKFGKHRYIANLGHGITPQTPL 296
++ F + R+I NLGHGI P+TP+
Sbjct: 309 VLANFAQGRFIFNLGHGIQPETPI 332
>UniRef50_A5EDY0 Cluster: Uroporphyrinogen decarboxylase; n=20;
Alphaproteobacteria|Rep: Uroporphyrinogen decarboxylase
- Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Length = 343
Score = 126 bits (303), Expect = 1e-27
Identities = 69/144 (47%), Positives = 88/144 (61%), Gaps = 3/144 (2%)
Query: 13 NDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVK-HDFFTVCRTPELACEVTLQPLR 71
N + G+ PVW+MRQAGRYLPE++EVR K F +C PE+A EVTLQP+R
Sbjct: 2 NKPFIDVLAGQRQSAPPVWMMRQAGRYLPEYREVRAKAGGFLDLCFNPEMAAEVTLQPIR 61
Query: 72 RYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYV 131
R+ DA+IIFSDILVIP ALG +V G GP PL TP +I L +++LD V
Sbjct: 62 RF-GFDAAIIFSDILVIPHALGRSVRFEVGEGPRL-DPLDTPEKIATLAGHADLTKLDAV 119
Query: 132 GKAITLTRHKIDGKVPLIGFTGAP 155
+A+ R ++ LIGF GAP
Sbjct: 120 FEALRRVRAELPKSTALIGFCGAP 143
Score = 78.6 bits (185), Expect = 2e-13
Identities = 45/142 (31%), Positives = 73/142 (51%), Gaps = 6/142 (4%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
+E+GA LQ+F++ A LS +F +S + I GVR + + P +GAG
Sbjct: 192 LEAGADALQIFDTWAGVLSPREFARWSAAPTRRIVEGVRNARPDAKIIGFP-----RGAG 246
Query: 216 HSLD-IQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMV 274
L A+ + + +DWT +P+ R+ V + +QGNLDP L + +++
Sbjct: 247 ALLPGYVAETAVDAVSIDWTAEPSLVRERVQSKVAVQGNLDPLALMTGGAALDQAVDDVL 306
Query: 275 KKFGKHRYIANLGHGITPQTPL 296
+ R+I NLGHGI P+TP+
Sbjct: 307 ASYAGGRHIFNLGHGILPETPI 328
>UniRef50_Q8FY24 Cluster: Uroporphyrinogen decarboxylase; n=12;
Alphaproteobacteria|Rep: Uroporphyrinogen decarboxylase
- Brucella suis
Length = 341
Score = 125 bits (302), Expect = 1e-27
Identities = 65/144 (45%), Positives = 93/144 (64%), Gaps = 4/144 (2%)
Query: 13 NDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVK-HDFFTVCRTPELACEVTLQPLR 71
N ++L+ G++V P+W+MRQAGRYLPE++E R K F +C +P+LA EVTLQP+R
Sbjct: 2 NRKVLKVIDGETVFPPPIWMMRQAGRYLPEYRETRKKAGSFLDLCYSPDLAVEVTLQPIR 61
Query: 72 RYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYV 131
R+ DA+I+FSDILV+P ALG + G GP+ P+ EI L+ EG RL+ V
Sbjct: 62 RF-GFDAAILFSDILVVPHALGRDLRFEEGKGPLM-TPIDA-DEIFWLETEGVAKRLEPV 118
Query: 132 GKAITLTRHKIDGKVPLIGFTGAP 155
+ + L R ++ + L+GF GAP
Sbjct: 119 YETVRLVREQLPDETTLLGFCGAP 142
Score = 67.7 bits (158), Expect = 4e-10
Identities = 45/143 (31%), Positives = 72/143 (50%), Gaps = 7/143 (4%)
Query: 158 SGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHS 217
+GA +Q+F+S + L + F F I + I VRA Q + F KGAG
Sbjct: 193 AGADAVQIFDSWSGVLDEDCFERFCIRPVARIVQKVRAVYP-----QARIIGFPKGAGML 247
Query: 218 L-DIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVKK 276
+ + G + +GLDW+V P ++ E +QGNLDP + + ++++
Sbjct: 248 YAGYREKTGVDMLGLDWSV-PLSFAALLQEEGAVQGNLDPLRVVAGGNALDEGVDAILER 306
Query: 277 FGKHRYIANLGHGITPQTPLESM 299
G+ + NLGHGITPQ P+E++
Sbjct: 307 MGQGPLVFNLGHGITPQAPIENV 329
>UniRef50_A6GDP1 Cluster: Uroporphyrinogen decarboxylase; n=1;
Plesiocystis pacifica SIR-1|Rep: Uroporphyrinogen
decarboxylase - Plesiocystis pacifica SIR-1
Length = 325
Score = 125 bits (301), Expect = 2e-27
Identities = 62/132 (46%), Positives = 90/132 (68%), Gaps = 3/132 (2%)
Query: 33 MRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRYEHLDASIIFSDILVIPQAL 92
MRQAGRYLPE++ +R K F +CRTPELA EVTLQP+ R + +DA+I+FSDILV+ A+
Sbjct: 1 MRQAGRYLPEYRAIRSKVSFLELCRTPELAAEVTLQPIDRLD-VDAAILFSDILVVFDAM 59
Query: 93 GMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAITLTRHKIDGKVPLIGFT 152
+ VE P GP P P++T ++++GL+ V L+YV A+ + + +VPLIGF
Sbjct: 60 DVAVEFKP--GPQLPSPVRTRADVEGLRWGEPVGELEYVMNAVRACKKALADRVPLIGFC 117
Query: 153 GAPVESGAQLLQ 164
GAP + + L++
Sbjct: 118 GAPFTTCSYLIE 129
Score = 94.3 bits (224), Expect = 4e-18
Identities = 48/156 (30%), Positives = 88/156 (56%), Gaps = 1/156 (0%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
+++G +Q+F+S A L + E +P+ + + V+A + E + VP+ +FA+G
Sbjct: 169 IDAGVDAVQIFDSWAGALGPRDYIEHVLPHTRTLVERVQAHIPEGRDQPVPVILFARGNM 228
Query: 216 HSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVK 275
+ L AQ+ + +G+DW++ +A +IVG + +QGNLDP L +PE I+ ++++
Sbjct: 229 NILGATAQVPADVVGVDWSIGMDQAIEIVGSDRVVQGNLDPGVLLGSPELIRDRVRDVLR 288
Query: 276 K-FGKHRYIANLGHGITPQTPLESMTVFTETVHEAI 310
+ G +I NLGHGI+ T + + VHE +
Sbjct: 289 EAAGAKAHIFNLGHGISRVTNPDHAKAMVDAVHEGL 324
>UniRef50_Q6MB12 Cluster: Uroporphyrinogen decarboxylase; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep:
Uroporphyrinogen decarboxylase - Protochlamydia
amoebophila (strain UWE25)
Length = 364
Score = 123 bits (297), Expect = 5e-27
Identities = 62/152 (40%), Positives = 97/152 (63%), Gaps = 3/152 (1%)
Query: 13 NDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRR 72
NDRLL+A ++ + PVW+MRQAGR+L ++ +R K+ F +C PEL EVTL P+
Sbjct: 28 NDRLLQALQCRNNSRPPVWLMRQAGRHLASYRALREKYSFLDMCHNPELIAEVTLLPIEA 87
Query: 73 YEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVG 132
Y+ +DA+I+FSDILVIP+AL + V VGP+ KP+ +I+ L ++ L++V
Sbjct: 88 YQ-VDAAILFSDILVIPEALKVGVRFEDKVGPIIEKPITNLHDIEKLAMPEDLTSLEFVK 146
Query: 133 KAITLTRHKIDGKVPLIGFTGAPVESGAQLLQ 164
+ I + +++ VPLIGF GAP + +++
Sbjct: 147 EGIRCLQPRLN--VPLIGFCGAPFTVASYMIE 176
Score = 93.1 bits (221), Expect = 8e-18
Identities = 58/164 (35%), Positives = 82/164 (50%), Gaps = 15/164 (9%)
Query: 149 IGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMT 208
I + +++G LQ+F+S A+ LS QF EFS+ YLK I G++ + +P+
Sbjct: 209 IAYLNMQIDAGVHALQIFDSWANTLSYRQFQEFSLNYLKYILKGLK--------KDIPLI 260
Query: 209 IFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLY----KTPE 264
+F +G+ A + +GLDW R ++ I LQGNLDP LY K E
Sbjct: 261 LFCRGSSVFGPDLASIKPAAVGLDWNCRVKRMRDVIPYPIALQGNLDPDLLYAPLPKIRE 320
Query: 265 EIKTLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
E+ L EM G +I NLGHGI P E++ ETV E
Sbjct: 321 EVNALLDEME---GDRGFILNLGHGIFPDVSEEAVRTLVETVRE 361
>UniRef50_Q01W10 Cluster: Uroporphyrinogen decarboxylase; n=1;
Solibacter usitatus Ellin6076|Rep: Uroporphyrinogen
decarboxylase - Solibacter usitatus (strain Ellin6076)
Length = 345
Score = 122 bits (293), Expect = 2e-26
Identities = 57/150 (38%), Positives = 91/150 (60%), Gaps = 2/150 (1%)
Query: 15 RLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRYE 74
R L A + D PVW MRQAGRY+ +++++R KH +C+ P+LA VTLQP+ +
Sbjct: 9 RFLDACRRRPTDVRPVWFMRQAGRYMKQYRQIREKHGILEICKRPDLAATVTLQPIEVLD 68
Query: 75 HLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKA 134
+DA+IIF+D+L+ + +G+ ++ G GPV P++T ++D L L YVG+A
Sbjct: 69 -VDAAIIFADLLLPIEPMGLKLKYEKGEGPVIGNPVRTSDDVDSLSTTN-TDELGYVGEA 126
Query: 135 ITLTRHKIDGKVPLIGFTGAPVESGAQLLQ 164
I + GKVP++GF GAP + +++
Sbjct: 127 IQHVVRALAGKVPVVGFVGAPFTMASYMIE 156
Score = 87.0 bits (206), Expect = 5e-16
Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 13/177 (7%)
Query: 136 TLTRHKIDGKVP--LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGV 193
TL R ++ GK+ L F + V +GA+ +QVF+S L + + F+ PY + + +
Sbjct: 175 TLWR-RLMGKIVDVLAPFAHSQVAAGARAIQVFDSWVGALGSDDYVRFAAPYSRALIERI 233
Query: 194 RAKLTEKSLEQVPMTIFAKGA-GHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQG 252
R+ VP+ F GA G ++ A G + +G+DW ++ +A + +QG
Sbjct: 234 RST-------GVPVIHFGTGASGFFRELHAA-GGDVMGVDWRINIDQAWMDISYRSAIQG 285
Query: 253 NLDPQDLYKTPEEIKTLTTEMVKKFG-KHRYIANLGHGITPQTPLESMTVFTETVHE 308
NLDP L+ E++T E++K+ G + +I NLGHGI P+TP+E++ E V E
Sbjct: 286 NLDPVALFAPLPELRTKVQELLKRTGTRPGHIFNLGHGILPETPVENVKAVVELVRE 342
>UniRef50_Q83H92 Cluster: Uroporphyrinogen decarboxylase; n=2;
Tropheryma whipplei|Rep: Uroporphyrinogen decarboxylase
- Tropheryma whipplei (strain TW08/27) (Whipple's
bacillus)
Length = 385
Score = 121 bits (291), Expect = 3e-26
Identities = 64/145 (44%), Positives = 90/145 (62%), Gaps = 5/145 (3%)
Query: 13 NDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRR 72
N ++ A G +PVW MRQAGR LPE++ VR + C P+LACE+TLQP+RR
Sbjct: 32 NTGIMEAFRGTRPGCLPVWFMRQAGRSLPEYRAVRGTNTLLEACLNPDLACEITLQPVRR 91
Query: 73 YEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVG 132
Y +DA+I+FSDI+V + G+ V++ PG GPV P+ TP ++ L + A S +D+ G
Sbjct: 92 YS-VDAAILFSDIVVPLKLAGVGVDILPGTGPVLNNPIDTPDRVNTLLAKTADS-IDF-G 148
Query: 133 KAITLTRHKID--GKVPLIGFTGAP 155
+TRH + +PLIGF GAP
Sbjct: 149 IIAEITRHTVSVLNGIPLIGFAGAP 173
Score = 86.6 bits (205), Expect = 7e-16
Identities = 51/169 (30%), Positives = 88/169 (52%), Gaps = 9/169 (5%)
Query: 151 FTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLK---DIRSGVRAKL----TEKSL- 202
F A + SGAQ +Q+F+S A LSR+ + + P+ K D+ G+ T KSL
Sbjct: 217 FLAAQITSGAQAVQIFDSWAGSLSRKDYVDNVAPFSKMTIDLACGIDGNSDLSKTGKSLW 276
Query: 203 EQVPMTIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKT 262
+VP+ FA AGH L +G + +D+T EA +++ +++ LQGN+DP L+
Sbjct: 277 PRVPVLHFAANAGHLLTAIRDIGVSVMSVDYTKPLDEASELLDDSMPLQGNIDPAMLFAP 336
Query: 263 PEEIKTLTTEMVKKFGK-HRYIANLGHGITPQTPLESMTVFTETVHEAI 310
E +K ++V++ + ++ NLGHG+ P + + + H +
Sbjct: 337 WEVLKRHVLDIVQRASRAPSHVLNLGHGVPPDASCDQLARIVDLAHSMV 385
>UniRef50_O22886 Cluster: Uroporphyrinogen decarboxylase,
chloroplast precursor; n=9; cellular organisms|Rep:
Uroporphyrinogen decarboxylase, chloroplast precursor -
Arabidopsis thaliana (Mouse-ear cress)
Length = 394
Score = 120 bits (289), Expect = 5e-26
Identities = 66/161 (40%), Positives = 95/161 (59%), Gaps = 5/161 (3%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
+I + +SGAQ +Q+F+S A LS F EFS+PYLK I V K T +L P+
Sbjct: 236 MITYIRYQADSGAQAVQIFDSWATELSPVDFEEFSLPYLKQIVEAV--KQTHPNL---PL 290
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
++A G+G L+ A+ G + + LDWTVD E R +G +I +QGN+DP L+ + E I
Sbjct: 291 ILYASGSGGLLERLARTGVDVVSLDWTVDMAEGRDRLGRDIAVQGNVDPGVLFGSKEFIT 350
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
+ + VKK G+ ++I NLGHGI TP E++ F E E
Sbjct: 351 SRIHDTVKKAGRDKHILNLGHGIKVGTPEENVAHFFEVAQE 391
Score = 90.6 bits (215), Expect = 4e-17
Identities = 47/150 (31%), Positives = 86/150 (57%), Gaps = 2/150 (1%)
Query: 16 LLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTV-CRTPELACEVTLQPLRRYE 74
LLRA G+ VD+ PVW+MRQAGRY+ +Q + K+ F +L E++LQP + ++
Sbjct: 56 LLRAVKGEVVDRPPVWLMRQAGRYMKSYQTLCEKYPSFRDRSENADLVVEISLQPWKVFK 115
Query: 75 HLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKA 134
D I+FSDIL + + ++ G GP+ P Q+ +++ ++ + YVG+A
Sbjct: 116 P-DGVILFSDILTPLSGMNIPFDIVKGKGPIIFNPPQSAADVAQVREFVPEESVPYVGEA 174
Query: 135 ITLTRHKIDGKVPLIGFTGAPVESGAQLLQ 164
+ R++++ + ++GF GAP + +++
Sbjct: 175 LRRLRNEVNNEAAVLGFVGAPFTLSSYVIE 204
>UniRef50_Q8XU90 Cluster: Uroporphyrinogen decarboxylase; n=258;
Proteobacteria|Rep: Uroporphyrinogen decarboxylase -
Ralstonia solanacearum (Pseudomonas solanacearum)
Length = 364
Score = 119 bits (287), Expect = 8e-26
Identities = 65/150 (43%), Positives = 93/150 (62%), Gaps = 7/150 (4%)
Query: 11 LKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVK-HDFFTVCRTPELACEVTLQP 69
L ND LRA + + P+W+MRQAGRYLPE+ R + F + ++P A EVTLQP
Sbjct: 5 LANDTFLRALRRQPTEYTPLWLMRQAGRYLPEYNATRARAGSFLGLAKSPAYATEVTLQP 64
Query: 70 LRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLD 129
L RY LDA+I+FSDIL +P A+G+ + G GP F +P+++ +++ L S L
Sbjct: 65 LDRYP-LDAAILFSDILTVPDAMGLGLSFEQGEGPRFARPVRSEADVAALSVPDMAS-LQ 122
Query: 130 YVGKAITLTRHKI--DG--KVPLIGFTGAP 155
YV A++ R + DG +VPLIGF+G+P
Sbjct: 123 YVFDAVSEIRRALVQDGRQRVPLIGFSGSP 152
Score = 102 bits (244), Expect = 1e-20
Identities = 55/164 (33%), Positives = 91/164 (55%), Gaps = 7/164 (4%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
+I + A +++GAQ + VF++ L+ + FS+ Y+ + G+RA ++VP+
Sbjct: 193 VIDYLNAQIDAGAQAVMVFDTWGGALADGIYQTFSLAYMARVVEGLRAGADG---QRVPV 249
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
+F KG G L+ AQ G + +G+DWTV+ AR G + LQGNLDP L+ P+ I+
Sbjct: 250 ILFTKGGGLWLESMAQTGADALGVDWTVNLQLARVRTGGRVALQGNLDPTVLFAEPDAIR 309
Query: 268 TLTTEMVKKFG----KHRYIANLGHGITPQTPLESMTVFTETVH 307
+++ + ++ NLGHGI+ TP ES+ V + VH
Sbjct: 310 AQVRRVLEDYAAGGDSDGHVFNLGHGISQFTPPESVAVLVDEVH 353
>UniRef50_Q9RV96 Cluster: Uroporphyrinogen decarboxylase; n=2;
Deinococcus radiodurans|Rep: Uroporphyrinogen
decarboxylase - Deinococcus radiodurans
Length = 344
Score = 119 bits (287), Expect = 8e-26
Identities = 56/146 (38%), Positives = 88/146 (60%), Gaps = 2/146 (1%)
Query: 11 LKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPL 70
+++ L+ A G+ PVW MRQAGRY+PE++ +R RTP+LA E+TLQP+
Sbjct: 1 MRDSAFLKTARGEQAPYTPVWFMRQAGRYMPEYRALRAGKTMLECIRTPDLAAEITLQPI 60
Query: 71 RRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDY 130
+ LDA+I+F+DIL +G++++ GVGPV P+ TP ++D L + Y
Sbjct: 61 KAMP-LDAAILFNDILTPLPTMGLSLDFVGGVGPVIHNPINTPKDVDVLGVPATAETMPY 119
Query: 131 VGKAITLTRHKIDGK-VPLIGFTGAP 155
++I L +++ + +PLIGF GAP
Sbjct: 120 TAESIRLLMPELNSRGIPLIGFVGAP 145
Score = 75.4 bits (177), Expect = 2e-12
Identities = 47/154 (30%), Positives = 80/154 (51%), Gaps = 8/154 (5%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
V++GA +Q+F+S LS + F +K +G+ ++ + VP+ F GA
Sbjct: 194 VKAGASAVQIFDSWVGALSVYDYQTF----VKPATAGLIERVKKLG---VPVIYFGTGAT 246
Query: 216 HSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVK 275
H + A LG + +G DW +A ++ ++QGNLDP L E+K T ++
Sbjct: 247 HLMPDMASLGSDVMGADWRTPLDKAWDLIQPGQSIQGNLDPLLLQAPWRELKHQTDRILH 306
Query: 276 KF-GKHRYIANLGHGITPQTPLESMTVFTETVHE 308
+ G+ +I N+GHG+ P+TP + + T+ VHE
Sbjct: 307 EANGRPGHIFNVGHGLLPETPQDMVHRLTDYVHE 340
>UniRef50_Q5FS38 Cluster: Uroporphyrinogen decarboxylase; n=6;
Alphaproteobacteria|Rep: Uroporphyrinogen decarboxylase
- Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 353
Score = 119 bits (286), Expect = 1e-25
Identities = 60/152 (39%), Positives = 98/152 (64%), Gaps = 3/152 (1%)
Query: 5 NKNFPELKNDR-LLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELAC 63
++N P + + LLRA G++V PVW+MRQAGRYLPEF+ +R + DF T C TP++A
Sbjct: 3 SENAPSSPSSKPLLRALRGEAVWPPPVWLMRQAGRYLPEFRAMRDRADFLTRCMTPDMAT 62
Query: 64 EVTLQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEG 123
E+T+QP+RRY +D +I+FSDIL++P A+G ++E G GPV +++ +++ L P+
Sbjct: 63 ELTIQPIRRY-GMDGAILFSDILILPWAMGQSLEFIDGRGPVL-GAIRSEADLARLDPKR 120
Query: 124 AVSRLDYVGKAITLTRHKIDGKVPLIGFTGAP 155
+ V + ++ ++ L+GF G+P
Sbjct: 121 VQDAVAPVRETLSRLTKELPDVTTLLGFAGSP 152
Score = 62.5 bits (145), Expect = 1e-08
Identities = 44/155 (28%), Positives = 72/155 (46%), Gaps = 9/155 (5%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
+E+GA+ + +F+S A L F + I + I +RA+ + P+ F + G
Sbjct: 201 IEAGAEAVMLFDSWAGILPPSAFRRYVIEPTRQIVEYIRARHPK-----TPIIGFPRLGG 255
Query: 216 HSLDIQAQ-LGYETIGLDWTVDPTEARKIVGE---NITLQGNLDPQDLYKTPEEIKTLTT 271
+ AQ G T+ LD DP + ++V E +TLQGN+DP L+ E +
Sbjct: 256 IMVREYAQKTGVNTLALDTVADPAQISELVSEVRPGLTLQGNMDPMILFSGGETMIREAQ 315
Query: 272 EMVKKFGKHRYIANLGHGITPQTPLESMTVFTETV 306
+ ++ NLGHG+ TP E++ E V
Sbjct: 316 AIRDAMRGKPHVFNLGHGVMQHTPPENVAALVEAV 350
>UniRef50_Q6AHF5 Cluster: Uroporphyrinogen decarboxylase; n=4;
Bacteria|Rep: Uroporphyrinogen decarboxylase - Leifsonia
xyli subsp. xyli
Length = 377
Score = 118 bits (285), Expect = 1e-25
Identities = 69/163 (42%), Positives = 100/163 (61%), Gaps = 7/163 (4%)
Query: 15 RLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRYE 74
RL+R+ G+ + PVW MRQAGR LPE++++RV VC P +A E+TLQP+RR+
Sbjct: 21 RLVRSYQGERQEVTPVWFMRQAGRSLPEYRDLRVGTRMLDVCLDPAMASEITLQPVRRH- 79
Query: 75 HLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGL---QPEG-AVSRLDY 130
+DA I FSDI+V + G+ VE+ PG GPVF + ++T +++D L P A
Sbjct: 80 GVDAGIFFSDIVVPLKLAGVEVEIQPGKGPVFERAVRTSADVDRLSAVDPAALAADTFAA 139
Query: 131 VGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQVFESSADHL 173
V +A+ LT +++ + PLIGF GAP A L++ S DHL
Sbjct: 140 VQEAVRLTTAELN-ETPLIGFAGAPFTLAAYLVE-GGPSKDHL 180
Score = 62.5 bits (145), Expect = 1e-08
Identities = 48/167 (28%), Positives = 76/167 (45%), Gaps = 10/167 (5%)
Query: 151 FTGAPVESGAQLLQVFESSADHLSREQFTEFSIP-------YLKDIRSGVRAKLT--EKS 201
F A V +GA Q+F+S A LS + E + P +++D+ V + E
Sbjct: 207 FLRAQVLAGASAAQLFDSWAGSLSLRDYAEHAAPASARAFSHVRDLTYTVPSADPDGEAV 266
Query: 202 LEQVPMTIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYK 261
+ VP+ F G G L + G + IG+D EA + +G + LQGN DP L
Sbjct: 267 VRAVPIVHFGVGTGELLPAMHEAGADAIGVDHRTLLDEASRRLGHIVPLQGNADPAMLAA 326
Query: 262 TPEEIKTLTTEMVKK-FGKHRYIANLGHGITPQTPLESMTVFTETVH 307
E + +++ + ++ NLGHG+ P+T +T E VH
Sbjct: 327 PWEVLSGHALDVLDRGRAAPAHVFNLGHGVPPETDPAVLTRVVELVH 373
>UniRef50_Q8FSD6 Cluster: Uroporphyrinogen decarboxylase; n=3;
Corynebacterium|Rep: Uroporphyrinogen decarboxylase -
Corynebacterium efficiens
Length = 359
Score = 116 bits (279), Expect = 8e-25
Identities = 65/154 (42%), Positives = 94/154 (61%), Gaps = 3/154 (1%)
Query: 11 LKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPL 70
L N LL AA GK+ + PVW MRQAGR LPE+ +VR C PEL E+T+QP+
Sbjct: 13 LNNAPLLDAAHGKTPTRTPVWFMRQAGRSLPEYLKVREGISMLDSCFMPELLAEITMQPV 72
Query: 71 RRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDY 130
RR++ +DA+I+FSDI+V +A G+ VE+ PG GPV +P++T ++ID L +
Sbjct: 73 RRHD-VDAAILFSDIVVPLRAAGVGVEIVPGRGPVMDQPVRTRADIDNLPI--LDHEVTE 129
Query: 131 VGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQ 164
V K I++ ++ LIGF GAP + L++
Sbjct: 130 VSKGISIILDELTDTQALIGFAGAPFTLASYLVE 163
Score = 70.5 bits (165), Expect = 5e-11
Identities = 51/170 (30%), Positives = 76/170 (44%), Gaps = 17/170 (10%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
++ F +++G +Q+F+S A L+ +TE +PY I L E Q+P
Sbjct: 195 VVNFLKTQIDAGIDAMQLFDSWAGFLTERDYTEHVLPYSTRI-------LQEVEQYQLPR 247
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARK---IVGENITLQGNLDPQDLYKTPE 264
F G G L ++ G E +G+DW V +A + V LQGNLDP L+ E
Sbjct: 248 IHFGVGTGELLGAMSRAGSEVMGVDWRVPLDKAAERIAAVSGPKVLQGNLDPALLFAGTE 307
Query: 265 ----EIKTLTTEMVKKFGKHR---YIANLGHGITPQTPLESMTVFTETVH 307
EI + E +I NLGHG+ P T E++T +H
Sbjct: 308 PLTREINRIKGEAAAAIAAGNATGHIFNLGHGVLPNTVAENITEAVSIIH 357
>UniRef50_Q7VF06 Cluster: Uroporphyrinogen decarboxylase; n=23;
Campylobacterales|Rep: Uroporphyrinogen decarboxylase -
Helicobacter hepaticus
Length = 340
Score = 114 bits (274), Expect = 3e-24
Identities = 60/138 (43%), Positives = 86/138 (62%), Gaps = 3/138 (2%)
Query: 19 AALGKSVDKVPVWVMRQAGRYLPEFQEVRVKH-DFFTVCRTPELACEVTLQPLRRYEHLD 77
A K P+W+MRQAGRYL E+++ R K F ++C+ ELA EVTLQP+ + +D
Sbjct: 6 ACFRKPTPYTPIWLMRQAGRYLSEYKQTRTKAGSFLSLCKNVELATEVTLQPVEILD-VD 64
Query: 78 ASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAITL 137
A+I+FSDILV+P +G+ +E G GP F + + S++ LQ EGA RL YV ++
Sbjct: 65 AAILFSDILVVPLEMGLPLEFLAGEGPKFNRTISNVSDVVNLQ-EGAHKRLTYVYDTLSS 123
Query: 138 TRHKIDGKVPLIGFTGAP 155
R K+ + LIGF G+P
Sbjct: 124 IRSKLPKEKALIGFCGSP 141
Score = 86.2 bits (204), Expect = 9e-16
Identities = 51/154 (33%), Positives = 79/154 (51%), Gaps = 8/154 (5%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
+ +GA +Q+F+S A L E + EFS Y+KDI ++ K +P+ +F KG
Sbjct: 190 IRAGANAVQIFDSWASALECEVYFEFSWKYMKDIAQYIKGK-----YPHIPVMLFPKGIA 244
Query: 216 HSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVK 275
LD + ++ G+DW A+ +G LQGNL+P LY E ++ E++K
Sbjct: 245 GYLD-KIDGCFDVFGVDWGTPMALAKSYLGTKYVLQGNLEPSRLY-DKESMERGIDEILK 302
Query: 276 KFGKHR-YIANLGHGITPQTPLESMTVFTETVHE 308
GK + +I NLGHG+ P P E+ + V E
Sbjct: 303 IMGKEKGHIFNLGHGMLPDLPRENAIALVQMVRE 336
>UniRef50_Q0BWA4 Cluster: Uroporphyrinogen decarboxylase; n=2;
Alphaproteobacteria|Rep: Uroporphyrinogen decarboxylase
- Hyphomonas neptunium (strain ATCC 15444)
Length = 344
Score = 113 bits (273), Expect = 4e-24
Identities = 61/141 (43%), Positives = 87/141 (61%), Gaps = 4/141 (2%)
Query: 17 LRAALGKSVDKVP-VWVMRQAGRYLPEFQEVRVK-HDFFTVCRTPELACEVTLQPLRRYE 74
L A L V KVP VW+MRQAGR+LPE+ E R + DF C TP LA E TLQP+RRY
Sbjct: 8 LLAGLSGEVFKVPPVWMMRQAGRHLPEYLETRARSKDFLDFCYTPSLASEATLQPIRRY- 66
Query: 75 HLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKA 134
+D +I+F+DIL+I A+G+ V G GP+ + + PS++ + P+ A RL V +
Sbjct: 67 GMDGAILFADILLILDAMGLKVAFEKGEGPLV-EQINGPSDLARVSPQKAADRLSPVYET 125
Query: 135 ITLTRHKIDGKVPLIGFTGAP 155
++ + + + LIGF G+P
Sbjct: 126 VSRVKAALPAQTTLIGFAGSP 146
Score = 66.1 bits (154), Expect = 1e-09
Identities = 45/155 (29%), Positives = 74/155 (47%), Gaps = 6/155 (3%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
VE+GA+ L +F+S A+ L F E I + + A L E+ + VP+ F +GAG
Sbjct: 195 VEAGAEALMLFDSWAEGLPDNIFREVVIAPTRKLV----ALLRERGIT-VPIIGFPRGAG 249
Query: 216 HSL-DIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMV 274
L + + G +GLD P + + +QG+LDP L + + E++
Sbjct: 250 VMLPEYVRETGVTAVGLDTAASPAFINAELAKGFPVQGHLDPLLLIEGGARLDARVRELL 309
Query: 275 KKFGKHRYIANLGHGITPQTPLESMTVFTETVHEA 309
+ +I NLGHG+ P+TP+ + E + A
Sbjct: 310 DAYRGRPHIFNLGHGVRPETPIAHVERVLELIRNA 344
>UniRef50_A6DLM9 Cluster: Uroporphyrinogen decarboxylase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Uroporphyrinogen
decarboxylase - Lentisphaera araneosa HTCC2155
Length = 343
Score = 112 bits (270), Expect = 1e-23
Identities = 56/140 (40%), Positives = 84/140 (60%), Gaps = 1/140 (0%)
Query: 16 LLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRYEH 75
LL ALGK ++ P+W+MRQAGRY+PE++ VR K F +C E A EVT+QP+ +
Sbjct: 4 LLDTALGKKCERTPIWLMRQAGRYMPEYRAVREKFSFLEMCMQYENAVEVTMQPIDILD- 62
Query: 76 LDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAI 135
+DA+I+FSDIL +G ++ + G GPV P++ ++ + DYV A+
Sbjct: 63 VDAAILFSDILTPLIPMGFDLKFYEGRGPVIHNPIENAEDVSRVVVPDVKKGSDYVYDAL 122
Query: 136 TLTRHKIDGKVPLIGFTGAP 155
+ R K+ + LIGF+GAP
Sbjct: 123 SAIRKKLSPEKDLIGFSGAP 142
Score = 88.6 bits (210), Expect = 2e-16
Identities = 52/152 (34%), Positives = 83/152 (54%), Gaps = 8/152 (5%)
Query: 157 ESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGH 216
++GAQ++Q+F+S LSRE + ++S PY I ++ + K P+ F KGA
Sbjct: 192 KAGAQIVQIFDSWGGVLSREDYLKYSHPYTVKIIDFIKKETGGK-----PVIHFVKGANA 246
Query: 217 SLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVKK 276
D A + +G DWT+ A+ + + LQGNLDP L+ +EI E++++
Sbjct: 247 YFDSVADSQADVLGTDWTLPLNVAKDLCNNSRVLQGNLDPASLFSN-KEILADKLELIRE 305
Query: 277 FGK--HRYIANLGHGITPQTPLESMTVFTETV 306
K +I NLGHGI P+TP+E++ +TV
Sbjct: 306 QAKGLKGHIFNLGHGIMPKTPVENVKFVVDTV 337
>UniRef50_Q42855 Cluster: Uroporphyrinogen decarboxylase; n=10;
Magnoliophyta|Rep: Uroporphyrinogen decarboxylase -
Hordeum vulgare (Barley)
Length = 330
Score = 112 bits (269), Expect = 1e-23
Identities = 59/148 (39%), Positives = 87/148 (58%), Gaps = 5/148 (3%)
Query: 157 ESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGH 216
++GAQ +Q+F+S A LS F EFS+PYLK I V+ ++ +P+ ++A G+G
Sbjct: 181 DNGAQAVQIFDSWATELSPVDFEEFSLPYLKQIVDSVK-----ETHPDLPLILYASGSGG 235
Query: 217 SLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVKK 276
L+ G + + LDWTVD E RK +G NI +QGN+DP L+ + E I + V+K
Sbjct: 236 LLERLPLTGVDVVSLDWTVDMAEGRKRLGSNIAVQGNVDPGVLFGSKEFITKRIYDTVQK 295
Query: 277 FGKHRYIANLGHGITPQTPLESMTVFTE 304
G ++ NLGHGI TP E++ F E
Sbjct: 296 AGSQGHVLNLGHGIKVGTPEENVAHFFE 323
Score = 84.6 bits (200), Expect = 3e-15
Identities = 44/132 (33%), Positives = 76/132 (57%), Gaps = 2/132 (1%)
Query: 25 VDKVPVWVMRQAGRYLPEFQEVRVKHDFFTV-CRTPELACEVTLQPLRRYEHLDASIIFS 83
V++ PVW+MRQAGRY+ +Q + K+ F +L E++LQP + ++ D I+FS
Sbjct: 1 VERPPVWLMRQAGRYMKSYQNLCEKYPLFRERSENVDLVVEISLQPWKVFKP-DGVILFS 59
Query: 84 DILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAITLTRHKID 143
DIL + + ++ G GPV PL+T + ++ ++ + YVG+A+ L R ++
Sbjct: 60 DILTPLPGMNIPFDIVKGKGPVIYDPLRTAAAVNEVREFVPEEWVPYVGQALNLLRGEVK 119
Query: 144 GKVPLIGFTGAP 155
+ ++GF GAP
Sbjct: 120 NEAAVLGFVGAP 131
>UniRef50_Q59269 Cluster: Uroporphyrinogen decarboxylase; n=4;
Alphaproteobacteria|Rep: Uroporphyrinogen decarboxylase
- Caulobacter crescentus (Caulobacter vibrioides)
Length = 351
Score = 112 bits (269), Expect = 1e-23
Identities = 70/150 (46%), Positives = 85/150 (56%), Gaps = 7/150 (4%)
Query: 9 PELKND-RLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVR-VKHDFFTVCRTPELACEVT 66
P LK + L A G+S PVW MRQAGRYLPE++ VR DF + C PE A EVT
Sbjct: 6 PILKQTPKFLSALEGQSHANPPVWFMRQAGRYLPEYRAVRATAPDFISFCFDPEKAAEVT 65
Query: 67 LQPLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVS 126
LQP+RR+ DASI+F+DIL+IP ALG V G G PK PS + G
Sbjct: 66 LQPMRRFP-FDASIVFADILLIPGALGQKVWFEAGEG---PKLGDMPSVESMAEKAGEAG 121
Query: 127 R-LDYVGKAITLTRHKIDGKVPLIGFTGAP 155
+ L VG+ +T R +D LIGF GAP
Sbjct: 122 KALSLVGETLTRVRSALDPDKALIGFAGAP 151
Score = 68.1 bits (159), Expect = 3e-10
Identities = 51/160 (31%), Positives = 83/160 (51%), Gaps = 9/160 (5%)
Query: 149 IGFTGAPVESGAQLLQVFESSADHLSREQFTEF-SIPYLKDIRSGVRAKLTEKSLEQVPM 207
I + V++GAQ L++FES A+ LS F + P+++ I G+RA+ VP+
Sbjct: 192 IDYLAMQVDAGAQALKLFESWAEGLSEPLFDRLVTQPHIRIIE-GLRARGVT-----VPI 245
Query: 208 TIFAKGAGHSL-DIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEI 266
F +GAG + D A+ + + LD T + + + + T+QG LDP L + +
Sbjct: 246 IGFPRGAGTLVEDYAARTPVQGVALD-TSASAKLGQTIQKTKTIQGALDPLLLRAGGDAL 304
Query: 267 KTLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETV 306
EM++++ + YI NLGHGI P TP+ + E V
Sbjct: 305 LKRVDEMLEQWNQGPYIFNLGHGILPDTPIAHVEAVLERV 344
>UniRef50_Q15GC6 Cluster: Uroporphyrinogen decarboxylase; n=1;
Guillardia theta|Rep: Uroporphyrinogen decarboxylase -
Guillardia theta (Cryptomonas phi)
Length = 404
Score = 111 bits (268), Expect = 2e-23
Identities = 62/153 (40%), Positives = 90/153 (58%), Gaps = 7/153 (4%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
+E+GAQ++Q+F+S A LS E + F+ PY K + + ++ K + VP+ I+ +G
Sbjct: 254 IEAGAQVIQIFDSWAGSLSPEDYDLFAFPYQKMVVNAIKKKHPD-----VPIIIYIAKSG 308
Query: 216 HSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVK 275
++ A G + + LDWTV EAR+ +G +I LQGNLDP LY PE I TE +
Sbjct: 309 AHVERMADTGVDIVSLDWTVTIDEARRRIGRDIGLQGNLDPAILY-GPEHIIKERTESIL 367
Query: 276 KFGKHR-YIANLGHGITPQTPLESMTVFTETVH 307
K K R +I NLGHGI TP ++ F +TVH
Sbjct: 368 KMAKGRHHIMNLGHGIEATTPQPNVKFFVDTVH 400
Score = 89.4 bits (212), Expect = 1e-16
Identities = 53/162 (32%), Positives = 90/162 (55%), Gaps = 4/162 (2%)
Query: 10 ELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTV-CRTPELACEVTLQ 68
++++ LLRAA G+ V+ PVW+MRQAGR++ E++E+ K+ F PE+A E++LQ
Sbjct: 60 KMEDPLLLRAARGEKVEMTPVWMMRQAGRHMQEYRELVKKYPTFRERSEIPEVATEISLQ 119
Query: 69 PLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGAVSR 127
P Y +D I+FSDIL +G+ ++ GP KPL+T +ID ++ +
Sbjct: 120 PWEAY-GVDGCILFSDILTPLPGMGVEFDIKETSGPKL-KPLRTKEQIDTMKICSDWSTS 177
Query: 128 LDYVGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQVFESS 169
+ +V + + R ++ ++GF G P L++ SS
Sbjct: 178 MPFVKQTLGELRKRVGNSATVLGFVGLPFTLATYLVEGGTSS 219
>UniRef50_Q019R2 Cluster: Uroporphyrinogen decarboxylase; n=2;
Ostreococcus|Rep: Uroporphyrinogen decarboxylase -
Ostreococcus tauri
Length = 410
Score = 109 bits (263), Expect = 7e-23
Identities = 62/149 (41%), Positives = 95/149 (63%), Gaps = 7/149 (4%)
Query: 13 NDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVR--VKHDFFTVCRTPELACEVTLQPL 70
ND ++RAA G+ V++ PVW+ RQAGR+LPE+ E + +F + P+ E T+QP+
Sbjct: 46 NDLMIRAARGERVERTPVWLFRQAGRHLPEYNEHKRARSKNFLELLADPKDVAECTMQPI 105
Query: 71 RRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVS-RLD 129
RRY +LDA+I+FSDILVI +AL + VEM G G + P PL+ P ++ + V+ +L
Sbjct: 106 RRY-NLDAAILFSDILVIAEALNVEVEMPGGKGILVPNPLKGPEDMGRVPKSIDVNDKLS 164
Query: 130 YVGKAITLTRHKIDGK---VPLIGFTGAP 155
+V ++ +I+ + VPLIGF+ AP
Sbjct: 165 HVLASVREINAQIEKEGLGVPLIGFSAAP 193
Score = 84.6 bits (200), Expect = 3e-15
Identities = 52/172 (30%), Positives = 93/172 (54%), Gaps = 17/172 (9%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
+I + A +E+G ++QVFE+ +H++ E F E+++P + I + VR + + +P+
Sbjct: 234 VIDYLCAQIENGVHMVQVFEAMCEHITEESFYEYAMPCMAKIAAEVRRRHPD-----IPI 288
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVG--------ENITLQGNLDPQDL 259
FA+ A + L Q GY+ I +D +D T AR ++ E +QGN DP L
Sbjct: 289 LGFARDAPYGLAALQQAGYDIITIDTAMDRTVARDVLRHDAEARGVEMSGVQGNFDPSLL 348
Query: 260 YK----TPEEIKTLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVH 307
K + E I+ T+M+ +FG + IANLG G++ + +E + +++H
Sbjct: 349 NKEGGSSFEGIEAEVTKMLTEFGPQKLIANLGAGLSGKEDVEKVAYLVDSIH 400
>UniRef50_Q1ITV2 Cluster: Uroporphyrinogen decarboxylase; n=5;
Bacteria|Rep: Uroporphyrinogen decarboxylase -
Acidobacteria bacterium (strain Ellin345)
Length = 351
Score = 109 bits (261), Expect = 1e-22
Identities = 63/194 (32%), Positives = 109/194 (56%), Gaps = 5/194 (2%)
Query: 13 NDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRR 72
N +RA + V++ PVW MRQAGRY+ E++ VR K+ +C+ P++A EVT+
Sbjct: 5 NSLFVRACKRQPVERTPVWFMRQAGRYMSEYRAVREKYSLVEICKKPDVAAEVTITAAEA 64
Query: 73 YEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVG 132
++DA+IIF+D+L+ + +G+ PG GPV P++ + I L+ + A L YV
Sbjct: 65 L-NVDAAIIFADLLLPLEVMGLPFHFSPGEGPVIEVPIRDAAHITRLRTDRA-HDLGYVA 122
Query: 133 KAITLTRHKIDGKVPLIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSG 192
+A+ K+P+IGF GAP + +++ S ++L ++ ++ P+ D G
Sbjct: 123 EAVKKVSDHFGSKLPVIGFCGAPFTLASYMIE-GGGSRNYLEVKKLM-YNSPHAWDELLG 180
Query: 193 -VRAKLTEKSLEQV 205
+ A L+E + +QV
Sbjct: 181 KLVAVLSEYTADQV 194
Score = 85.8 bits (203), Expect = 1e-15
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 7/159 (4%)
Query: 151 FTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIF 210
+T V++GA ++Q+F+S LS E + + +P ++ K + S +VP+ F
Sbjct: 189 YTADQVKAGADVIQIFDSWVGCLSVEDYRRYVLPRTTEL-----VKALQHST-RVPIIYF 242
Query: 211 AKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLT 270
+ L + G E IGLDW V + ++ ++ +QGNLDP L+ E+K+
Sbjct: 243 GTDSATLLPSMRETGAEVIGLDWRVPLDQGWSLLEHSVAIQGNLDPVLLFAEWPELKSRA 302
Query: 271 TEMVKKF-GKHRYIANLGHGITPQTPLESMTVFTETVHE 308
++K+ G+ +I NLGHGI P TP++++ + VHE
Sbjct: 303 ERILKQADGRPGHIFNLGHGILPHTPVQNVKDLAKFVHE 341
>UniRef50_Q01G98 Cluster: Uroporphyrinogen decarboxylase; n=2;
Ostreococcus|Rep: Uroporphyrinogen decarboxylase -
Ostreococcus tauri
Length = 394
Score = 109 bits (261), Expect = 1e-22
Identities = 57/155 (36%), Positives = 87/155 (56%), Gaps = 5/155 (3%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
+ESGAQ++Q+F+S A HLS +QF EFS PY + I + V+ + E P+ A G
Sbjct: 237 IESGAQVVQIFDSWAHHLSPQQFLEFSHPYNERIIAYVKERHPE-----TPLIFHANGGC 291
Query: 216 HSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVK 275
L+ + + IGLDW +AR ++G + LQGN+DP L+ +PE IK V+
Sbjct: 292 GKLNELKKSTADVIGLDWNTSMVDARAVLGPDRVLQGNMDPMYLFASPERIKQEVANCVR 351
Query: 276 KFGKHRYIANLGHGITPQTPLESMTVFTETVHEAI 310
G ++I N+GHG+ TP ES+ F + ++
Sbjct: 352 DAGSSKHILNVGHGVVQGTPEESVGHFCDAARASV 386
Score = 100 bits (240), Expect = 4e-20
Identities = 59/159 (37%), Positives = 95/159 (59%), Gaps = 5/159 (3%)
Query: 16 LLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRYEH 75
LLRAA G+ V++ PVW+MRQAGRY+ EF+ K+ F TPE+A E+++QP R Y+
Sbjct: 50 LLRAARGEDVERSPVWLMRQAGRYMAEFRAYSTKYGFRHRSETPEIAIELSMQPWRAYKP 109
Query: 76 LDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQP-EGAVSRLDYVGKA 134
D I+FSDIL ALG+ ++ G GPV + +++ ++ ++ + L +V +
Sbjct: 110 -DGVIMFSDILTPLPALGIEFDVVKGKGPVVHQ-VKSMDDVRAMKTLDDPEKSLPFVREI 167
Query: 135 ITLTRHKIDGKVPLIGFTGAPVESGAQLLQVFESSADHL 173
++ R +IDG+ ++GF G+P A ++ SS HL
Sbjct: 168 LSSLRKEIDGQSTMLGFIGSPWTLAAYAME--GSSDRHL 204
>UniRef50_A3VQ61 Cluster: Uroporphyrinogen decarboxylase; n=1;
Parvularcula bermudensis HTCC2503|Rep: Uroporphyrinogen
decarboxylase - Parvularcula bermudensis HTCC2503
Length = 340
Score = 108 bits (260), Expect = 2e-22
Identities = 59/142 (41%), Positives = 84/142 (59%), Gaps = 3/142 (2%)
Query: 16 LLRAALGKSVDKVP-VWVMRQAGRYLPEFQEVRVKHD-FFTVCRTPELACEVTLQPLRRY 73
LL + L +V ++P +W MRQAGRYLPE++++R F +C TPE A VTLQP+ RY
Sbjct: 3 LLTSVLRGTVQEIPPIWFMRQAGRYLPEYRDLRANAGGFLDLCYTPEKAARVTLQPIDRY 62
Query: 74 EHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGK 133
+ LDA+I+F+DIL++PQALGM + PG GP L + RL + +
Sbjct: 63 D-LDAAILFADILLVPQALGMDLWFEPGEGPRLAPALAEGDAAVLFEQRDIHDRLGPIYE 121
Query: 134 AITLTRHKIDGKVPLIGFTGAP 155
++ R + + LIGF GAP
Sbjct: 122 TVSRVRAALPQEKALIGFAGAP 143
Score = 58.8 bits (136), Expect = 2e-07
Identities = 40/159 (25%), Positives = 73/159 (45%), Gaps = 7/159 (4%)
Query: 149 IGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMT 208
I + V++GA+++Q+F+S A L F +F + + I + +RA +P+
Sbjct: 185 IDYLKKQVDAGAEVIQLFDSWAGGLPEALFDQFCVAPVARIAAALRAHA------DIPVI 238
Query: 209 IFAKGAGHSL-DIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
F +G+G I A + +D + A + + +QG LDP + K E+
Sbjct: 239 GFPRGSGPLYRKIAALPDIAAVSIDTGMPADWAAEALSPLAVVQGGLDPLLIVKGGTEML 298
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETV 306
++ F ++ N+GHG+ PQTP E++ V
Sbjct: 299 KAADQLRASFEGRPFVFNVGHGLVPQTPPENVAALVNHV 337
>UniRef50_P42503 Cluster: Uroporphyrinogen decarboxylase; n=14;
Alphaproteobacteria|Rep: Uroporphyrinogen decarboxylase
- Rhodobacter capsulatus (Rhodopseudomonas capsulata)
Length = 344
Score = 108 bits (259), Expect = 2e-22
Identities = 58/142 (40%), Positives = 88/142 (61%), Gaps = 4/142 (2%)
Query: 16 LLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVK-HDFFTVCRTPELACEVTLQPLRRYE 74
+LRA G+ + PVW+MRQAGRYLPE++ R + DF ++C TP+LA EVTLQP+RRY
Sbjct: 6 ILRALKGEVLPTPPVWLMRQAGRYLPEYRATRAQAGDFLSLCYTPDLAAEVTLQPIRRY- 64
Query: 75 HLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAV-SRLDYVGK 133
DA+I+F+DIL++PQALG+ + G GP + + + GL+ + + +L V +
Sbjct: 65 GFDAAILFADILLLPQALGLDLWFETGEGPRM-STVTSMEGVKGLKGKDDIHDKLAPVYE 123
Query: 134 AITLTRHKIDGKVPLIGFTGAP 155
+ ++ + IGF G P
Sbjct: 124 TCKILSRELPKETTFIGFAGMP 145
Score = 73.3 bits (172), Expect = 7e-12
Identities = 45/165 (27%), Positives = 87/165 (52%), Gaps = 7/165 (4%)
Query: 146 VPLIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQV 205
V I + VE+G +++++F+S A L + F +F++ + I + ++ + +
Sbjct: 184 VATIEYLSKQVEAGCEVVKLFDSWAGSLKGQDFEDFAVEPARVITAEMKRRFPG-----L 238
Query: 206 PMTIFAKGAGHS-LDIQAQLGYETIGLDWTVDPTEARKIVGENIT-LQGNLDPQDLYKTP 263
P+ F + AG + + G + + +D +V P A + V + T +QGNLDP +
Sbjct: 239 PVIAFPREAGQGYIGFAEKTGADCVAIDNSVSPDWAAENVQKGKTCVQGNLDPSYMVTGG 298
Query: 264 EEIKTLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
+E+ T ++V F +I NLGHGITP+ +++T+ ET+ +
Sbjct: 299 QELVEATKKVVAAFKNGPHIFNLGHGITPEANPDNVTLLMETIRK 343
>UniRef50_Q5L284 Cluster: Uroporphyrinogen decarboxylase; n=5;
Bacteria|Rep: Uroporphyrinogen decarboxylase -
Geobacillus kaustophilus
Length = 347
Score = 107 bits (257), Expect = 4e-22
Identities = 58/164 (35%), Positives = 92/164 (56%), Gaps = 4/164 (2%)
Query: 13 NDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRR 72
ND LRA G+ VPVW MRQAGR PE++ ++ K+ F + PEL VT P+ +
Sbjct: 8 NDTFLRACRGEQTSYVPVWYMRQAGRSQPEYRALKEKYSLFEITHQPELCAYVTRLPVEQ 67
Query: 73 YEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVG 132
Y +DA+I++ DI+ A+G+ VE+ G+GPV P+++ +++ L + YV
Sbjct: 68 Y-GVDAAILYKDIMTPLPAIGVNVEIQGGIGPVIANPIRSLQDVERLGEIDPEHDVPYVF 126
Query: 133 KAI-TLTRHKIDGKVPLIGFTGAPVESGAQLLQVFESSADHLSR 175
+ I L ++D VPLIGF GAP + +++ S H ++
Sbjct: 127 ETIRLLVNEQLD--VPLIGFAGAPFTLASYMIEGGPSKNYHKTK 168
Score = 70.9 bits (166), Expect = 4e-11
Identities = 51/164 (31%), Positives = 78/164 (47%), Gaps = 15/164 (9%)
Query: 149 IGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMT 208
I + A + +GA +Q+F+S +S + + F P + I + +R E P+
Sbjct: 190 IRYVRAQIRAGASAVQIFDSWVGAVSADDYRTFIKPAMARIFAALRE-------EGAPLI 242
Query: 209 IFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYK----TPE 264
+F GA H + L + IGLDW + EAR+ G +QGNLDP L E
Sbjct: 243 MFGVGASHLVHEWNDLPLDVIGLDWRLSIREARR-QGIAKAIQGNLDPAVLLAPWDVIEE 301
Query: 265 EIKTLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
+K + E +++ G YI NLGHGI P ++ T +HE
Sbjct: 302 RVKRILDEGMERPG---YIFNLGHGIFPDVQPATLKRLTAFIHE 342
>UniRef50_Q2GCG4 Cluster: Uroporphyrinogen decarboxylase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep:
Uroporphyrinogen decarboxylase - Neorickettsia sennetsu
(strain Miyayama)
Length = 324
Score = 107 bits (257), Expect = 4e-22
Identities = 52/129 (40%), Positives = 80/129 (62%), Gaps = 5/129 (3%)
Query: 27 KVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRYEHLDASIIFSDIL 86
K+ W MRQAGRYLPE+ ++ + FF +C +PE+A E+TLQP++R++ LDA+I+FSDIL
Sbjct: 7 KISTWFMRQAGRYLPEYLKISKEMTFFQMCESPEIASEITLQPIKRFD-LDAAIVFSDIL 65
Query: 87 VIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAITLTRHKIDGKV 146
V+P+ALG +++ GPV + + P + L + ++ I +TR +
Sbjct: 66 VLPRALGCNIDIKKSTGPVIER-INNP---NWLTYDAFEEKISPTLNTIAITRKSLPQNK 121
Query: 147 PLIGFTGAP 155
LIGF G P
Sbjct: 122 SLIGFAGGP 130
Score = 63.3 bits (147), Expect = 8e-09
Identities = 47/152 (30%), Positives = 70/152 (46%), Gaps = 11/152 (7%)
Query: 149 IGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMT 208
I + ++ GA +Q+FES A S +F EF + + I S + VP+
Sbjct: 172 IQYLNKQLKHGADFIQIFESFAWAASSNEFKEFIVEPTRRIVSSI----------DVPVI 221
Query: 209 IFAKGAGHS-LDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
F KGAG S L + + I D ++ + + +QGNLDP L +E
Sbjct: 222 GFPKGAGVSYLQYVKETSVDVISTDHSLPLDWIADNLQTHAVVQGNLDPYLLAFNKKEAL 281
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESM 299
T +V F + +I NLGHGI +TPL S+
Sbjct: 282 LQTERIVDAFSEKNFIFNLGHGIYKETPLSSV 313
>UniRef50_P32395 Cluster: Uroporphyrinogen decarboxylase; n=52;
Bacillales|Rep: Uroporphyrinogen decarboxylase -
Bacillus subtilis
Length = 353
Score = 106 bits (255), Expect = 6e-22
Identities = 55/155 (35%), Positives = 93/155 (60%), Gaps = 2/155 (1%)
Query: 10 ELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQP 69
E N+ L+AA G+ D PVW MRQAGR PE+++++ K+ F + PEL VT P
Sbjct: 5 ETFNETFLKAARGEKADHTPVWYMRQAGRSQPEYRKLKEKYGLFEITHQPELCAYVTRLP 64
Query: 70 LRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLD 129
+ +Y +DA+I++ DI+ ++G+ VE+ G+GPV +P+++ ++I+ L +
Sbjct: 65 VEQY-GVDAAILYKDIMTPLPSIGVDVEIKNGIGPVIDQPIRSLADIEKLGQIDPEQDVP 123
Query: 130 YVGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQ 164
YV + I L ++ VPLIGF+GAP + +++
Sbjct: 124 YVLETIKLLVNE-QLNVPLIGFSGAPFTLASYMIE 157
Score = 80.2 bits (189), Expect = 6e-14
Identities = 52/162 (32%), Positives = 83/162 (51%), Gaps = 9/162 (5%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
+I + A +E+GA+ +Q+F+S L++ + Y+K + + + ++L + E VP+
Sbjct: 189 IIVYVKAQIEAGAKAIQIFDSWVGALNQADYRT----YIKPVMNRIFSELAK---ENVPL 241
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
+F GA H L + +GLDW + EAR G T+QGNLDP L E I+
Sbjct: 242 IMFGVGASHLAGDWHDLPLDVVGLDWRLGIDEARS-KGITKTVQGNLDPSILLAPWEVIE 300
Query: 268 TLTTEMVKK-FGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
T E++ + +I NLGHG+ P E + T VHE
Sbjct: 301 QKTKEILDQGMESDGFIFNLGHGVFPDVSPEVLKKLTAFVHE 342
>UniRef50_Q7UN37 Cluster: Uroporphyrinogen III synthase,
uroporhyrinogen decarboxylase; n=2;
Planctomycetaceae|Rep: Uroporphyrinogen III synthase,
uroporhyrinogen decarboxylase - Rhodopirellula baltica
Length = 673
Score = 106 bits (254), Expect = 8e-22
Identities = 52/139 (37%), Positives = 83/139 (59%), Gaps = 1/139 (0%)
Query: 17 LRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRYEHL 76
+RA G+ + PVW+MRQAGRY+ E++EVR + F +C P+L EV + + ++
Sbjct: 326 MRACRGEPTPRTPVWMMRQAGRYMQEYREVRSQQSFLELCANPKLCSEVMCTAVEKL-NV 384
Query: 77 DASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAIT 136
DA+IIFSD+L I +G +E G GPV P+++ +++D ++ L +V + +
Sbjct: 385 DAAIIFSDLLPILVPMGFDLEFVKGDGPVIHNPVRSAADVDRVKGLDNPQDLGFVYETVK 444
Query: 137 LTRHKIDGKVPLIGFTGAP 155
TR + +PLIGF GAP
Sbjct: 445 QTRADLPEGIPLIGFAGAP 463
Score = 86.2 bits (204), Expect = 9e-16
Identities = 53/162 (32%), Positives = 84/162 (51%), Gaps = 9/162 (5%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
+I + + +GAQ +Q+F+S A LS + EF +P++K I GV VP+
Sbjct: 504 IIVYLNEQISAGAQCVQLFDSWAGCLSPGDYREFVLPWMKRILEGVTPG--------VPL 555
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
FA G L + +G+DW ++ A K VG +I++QGNLDP L + I+
Sbjct: 556 INFATGNPELLPLLRGDRRTVVGVDWRIELDVAWKRVGHDISVQGNLDPSVLLTDAKTIR 615
Query: 268 TLTTEMVKKF-GKHRYIANLGHGITPQTPLESMTVFTETVHE 308
+++ K G+ +I NLGHG+ QTP+E+ + V E
Sbjct: 616 AAVQDVLNKAGGRPGHIFNLGHGVLQQTPVENAIELVKAVKE 657
>UniRef50_Q8NT75 Cluster: Uroporphyrinogen decarboxylase; n=45;
Bacteria|Rep: Uroporphyrinogen decarboxylase -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 358
Score = 106 bits (254), Expect = 8e-22
Identities = 61/155 (39%), Positives = 93/155 (60%), Gaps = 5/155 (3%)
Query: 11 LKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPL 70
L N ++ AA GK+ + PVW MRQAGR LPE+++VR C PEL E+TLQP+
Sbjct: 13 LNNAPIIDAANGKTPTRTPVWFMRQAGRSLPEYKKVREGISMLDSCFMPELLAEITLQPV 72
Query: 71 RRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQ-PEGAVSRLD 129
RR++ +DA+I+FSDI+V +A G+ VE+ G GPV P+++ ++ L EG V ++
Sbjct: 73 RRHD-VDAAILFSDIVVPLRAAGVGVEIVAGRGPVLDAPVRSRGDVLNLPILEGNVPEVE 131
Query: 130 YVGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQ 164
+ I + ++ LIGF GAP + L++
Sbjct: 132 ---QGIGIILDELSDSQALIGFAGAPFTLASYLVE 163
>UniRef50_Q2GLU4 Cluster: Uroporphyrinogen decarboxylase; n=2;
Anaplasma|Rep: Uroporphyrinogen decarboxylase -
Anaplasma phagocytophilum (strain HZ)
Length = 343
Score = 105 bits (253), Expect = 1e-21
Identities = 62/167 (37%), Positives = 93/167 (55%), Gaps = 7/167 (4%)
Query: 23 KSVDKVPVWVMRQAGRYLPEFQEVRVK-HDFFTVCRTPELACEVTLQPLRRYEHLDASII 81
+S ++P+W MRQAGRYLPE+Q+V DF C TPE+ EVTLQP++R++ LDA+II
Sbjct: 22 RSTQRLPIWFMRQAGRYLPEYQKVMAHVQDFLEACYTPEIVEEVTLQPIQRFD-LDAAII 80
Query: 82 FSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAITLTRHK 141
FSDI+ +P ALG V G GP +T E+ E ++ ++ V ++I R
Sbjct: 81 FSDIMTVPDALGFEVVFKRGYGPQI--NAKTRREV---TLEWSLEKVSPVLESIKRVRKS 135
Query: 142 IDGKVPLIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKD 188
+ LIGF G+P +L+ + D + + + S+ L D
Sbjct: 136 LSPNKSLIGFAGSPWTVATYILEQEKKITDIFALHRSGDNSVAKLID 182
Score = 54.0 bits (124), Expect = 5e-06
Identities = 46/147 (31%), Positives = 71/147 (48%), Gaps = 12/147 (8%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
VE G +LQ+F+S+A L + F F + + I +R K +P+ F KGAG
Sbjct: 196 VEYGVDILQLFDSNASGLPVDLFETFIVEPTQRIVKELR-----KHHPSIPIIGFPKGAG 250
Query: 216 HSLDIQA-QLGYETIGLDWTVDPTEARKIVGENIT--LQGNLDPQDLYKTPEEIKTLTTE 272
A G + +D+++ P++ K NI+ +QGNLDP L E E
Sbjct: 251 VLYTHYALTTGISAVSVDYSI-PSQWIK---NNISGVVQGNLDPFLLAYDVEGALKCAGE 306
Query: 273 MVKKFGKHRYIANLGHGITPQTPLESM 299
++ I NLGHGI P TP++++
Sbjct: 307 IIADLRDKPLIFNLGHGIIPPTPVDNV 333
>UniRef50_A5H0C9 Cluster: Uroporphyrinogen decarboxylase; n=39;
Rickettsiales|Rep: Uroporphyrinogen decarboxylase -
Wolbachia endosymbiont of Drosophila melanogaster
Length = 338
Score = 103 bits (246), Expect = 8e-21
Identities = 54/130 (41%), Positives = 83/130 (63%), Gaps = 5/130 (3%)
Query: 27 KVPVWVMRQAGRYLPEFQE-VRVKHDFFTVCRTPELACEVTLQPLRRYEHLDASIIFSDI 85
+VP+W+MRQAGR LPE+++ V ++F +C +L E+TLQP+ R++ +DA+IIFSDI
Sbjct: 20 RVPIWLMRQAGRSLPEYRKAVENMNNFMEICYNTDLVTELTLQPVTRFD-MDAAIIFSDI 78
Query: 86 LVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAITLTRHKIDGK 145
L+I LG V GVGP+ KP+++P E+ G P+ ++ + AI R ++ +
Sbjct: 79 LIIADVLGCDVNFVRGVGPII-KPVESPKELKG--PQEIETKTLPILNAIKKVRSQLPKE 135
Query: 146 VPLIGFTGAP 155
LIGF G P
Sbjct: 136 KSLIGFAGGP 145
Score = 71.3 bits (167), Expect = 3e-11
Identities = 51/153 (33%), Positives = 77/153 (50%), Gaps = 10/153 (6%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
+E GA ++Q+F+S+A LS F E+ I K I ++ + ++ P+ F + AG
Sbjct: 191 IEFGADVIQLFDSNAGALSEPLFKEYVIEPTKRIILAIKDRFSD-----FPIIGFPRSAG 245
Query: 216 HSL-DIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDL-YKTPEEIKTLTTEM 273
+ D Q G + +D+ V P + K NI LQGNLDP L Y E IK +
Sbjct: 246 NLYKDYCEQTGVSAVSIDYNV-PIKWAK-ANLNIPLQGNLDPNLLAYNKTEAIKE-AKRI 302
Query: 274 VKKFGKHRYIANLGHGITPQTPLESMTVFTETV 306
+ F +I NLGHG+ P TP+E++ V
Sbjct: 303 IDCFRDLPFIFNLGHGVLPDTPVENIAALVNLV 335
>UniRef50_Q92FV3 Cluster: Uroporphyrinogen decarboxylase; n=10;
Rickettsia|Rep: Uroporphyrinogen decarboxylase -
Rickettsia conorii
Length = 346
Score = 103 bits (246), Expect = 8e-21
Identities = 56/131 (42%), Positives = 80/131 (61%), Gaps = 4/131 (3%)
Query: 26 DKVPVWVMRQAGRYLPEFQEVR-VKHDFFTVCRTPELACEVTLQPLRRYEHLDASIIFSD 84
+KVP+W MRQAGRYLPE+++VR +F C A EVTLQP++RY DA+IIFSD
Sbjct: 13 NKVPIWFMRQAGRYLPEYKKVRETTKNFLDFCYDVSKATEVTLQPIKRY-GFDAAIIFSD 71
Query: 85 ILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAITLTRHKIDG 144
ILV+P ALG V+ +GP+ K ++ + LQ +L+ V + I + ++
Sbjct: 72 ILVLPHALGWEVDFKENIGPIL-KQFKSQEDFKYLQINPNY-KLEKVYEIIKKVKKELPS 129
Query: 145 KVPLIGFTGAP 155
+ LIGF G+P
Sbjct: 130 PISLIGFAGSP 140
Score = 79.0 bits (186), Expect = 1e-13
Identities = 52/151 (34%), Positives = 81/151 (53%), Gaps = 7/151 (4%)
Query: 157 ESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGH 216
+SGA +L++F+S + L+ E+FTEF I K I V+ + + P+ F KGAG
Sbjct: 190 KSGADVLKLFDSWSGVLAEEEFTEFVIEPTKKIILKVK-----EVFPKTPIIAFPKGAGL 244
Query: 217 SLD-IQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVK 275
+ ++ + + +D V P E K + + +QGNLDP L E IK T ++++
Sbjct: 245 LYEKFIKEVPIDVLAVDQMV-PLEKMKEWSDKVIVQGNLDPVVLLTNKEIIKEKTYKILQ 303
Query: 276 KFGKHRYIANLGHGITPQTPLESMTVFTETV 306
+I NLGHGI P+TP E++ TE V
Sbjct: 304 VMKGKNFIFNLGHGILPETPTENVEFLTEYV 334
>UniRef50_A5CDS4 Cluster: Uroporphyrinogen decarboxylase; n=1;
Orientia tsutsugamushi Boryong|Rep: Uroporphyrinogen
decarboxylase - Orientia tsutsugamushi (strain Boryong)
(Rickettsia tsutsugamushi)
Length = 342
Score = 102 bits (245), Expect = 1e-20
Identities = 54/142 (38%), Positives = 87/142 (61%), Gaps = 5/142 (3%)
Query: 15 RLLRAALGKSVDKVPVWVMRQAGRYLPEFQEV-RVKHDFFTVCRTPELACEVTLQPLRRY 73
++++A + + P+W MRQAGRYLPE+Q + R + FF +C P A E TLQP+ R+
Sbjct: 3 KIIQAFHSSNKNYTPIWFMRQAGRYLPEYQVLKRTTNSFFELCYNPIKAAEATLQPIARF 62
Query: 74 EHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGK 133
+ DA+IIFSDILV+P +LG+ + + + P + P+ +D + + +++ V +
Sbjct: 63 D-FDAAIIFSDILVLPDSLGINIRF---INNLCPTAEKIPNLLDLQKSKIQNTKISKVYE 118
Query: 134 AITLTRHKIDGKVPLIGFTGAP 155
AI + R K++ K LIGF G P
Sbjct: 119 AIDIVRKKLNKKKSLIGFCGGP 140
Score = 65.7 bits (153), Expect = 1e-09
Identities = 42/151 (27%), Positives = 79/151 (52%), Gaps = 8/151 (5%)
Query: 158 SGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHS 217
+GA ++Q+F+S A L ++F+E+ I +I K ++ + + F KGAG
Sbjct: 191 AGADIVQIFDSWAGILPYQEFSEYVIKPTSNI-----VKTLKEKFPHIKIIGFPKGAGKL 245
Query: 218 LD-IQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQD-LYKTPEEIKTLTTEMVK 275
+ + I D+ + E K+ +N+ +QGNL+P L K + I+ +++
Sbjct: 246 YHKYTKETNVDGISCDYDLQLDEMLKLQ-KNVLVQGNLNPNTILSKNSKIIEESVIKIMD 304
Query: 276 KFGKHRYIANLGHGITPQTPLESMTVFTETV 306
+R+I NLGHGI P+TP++++ + + V
Sbjct: 305 TLSNNRFIFNLGHGILPETPIKNVELIVKLV 335
>UniRef50_Q7U645 Cluster: Uroporphyrinogen decarboxylase; n=44;
cellular organisms|Rep: Uroporphyrinogen decarboxylase -
Synechococcus sp. (strain WH8102)
Length = 352
Score = 101 bits (242), Expect = 2e-20
Identities = 54/147 (36%), Positives = 83/147 (56%), Gaps = 5/147 (3%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
++SGAQ++Q+F+S A LS + F+ PY K + L +++ P ++ G+
Sbjct: 196 IDSGAQVVQMFDSWAGQLSPADYDTFAAPYQKKV-----VDLVKQTHPDTPFILYISGSA 250
Query: 216 HSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVK 275
L+ A G + I LDWTVD EA + E+I +QGN+DP L+ TP+ I+ + V+
Sbjct: 251 GVLERMATTGVDIISLDWTVDMGEALARLPEHIGVQGNVDPGLLFGTPDAIEARIDDCVR 310
Query: 276 KFGKHRYIANLGHGITPQTPLESMTVF 302
K ++I NLGHGI P TP E+ F
Sbjct: 311 KARGRKHILNLGHGILPGTPEENGAAF 337
Score = 97.1 bits (231), Expect = 5e-19
Identities = 47/150 (31%), Positives = 88/150 (58%), Gaps = 2/150 (1%)
Query: 16 LLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTV-CRTPELACEVTLQPLRRYE 74
LLRAA G++V++ PVW+MRQAGRY+ ++++R K+ F P+L+ E+++QP ++
Sbjct: 8 LLRAARGEAVERPPVWMMRQAGRYMKIYRDLRDKYPSFRERSENPDLSYEISMQPFHAFK 67
Query: 75 HLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKA 134
D I+FSDIL +G+ ++ GP P+++ +++ L+P + +VG+
Sbjct: 68 P-DGVILFSDILTPLPGMGIDFDIIESKGPQIGDPIRSMDQVNALRPLNPSESMPFVGEV 126
Query: 135 ITLTRHKIDGKVPLIGFTGAPVESGAQLLQ 164
+ R + + ++GF GAP A +++
Sbjct: 127 LGRLRESVGNEAAVLGFVGAPWTLAAYVVE 156
>UniRef50_UPI00015BC740 Cluster: UPI00015BC740 related cluster; n=1;
unknown|Rep: UPI00015BC740 UniRef100 entry - unknown
Length = 347
Score = 100 bits (240), Expect = 4e-20
Identities = 62/169 (36%), Positives = 95/169 (56%), Gaps = 9/169 (5%)
Query: 11 LKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKH-DFFTVCRTPELACEVTLQP 69
+KND L++ + + + PVW+MRQAGRYLPE++ +R K+ F C+ E A V+LQP
Sbjct: 1 MKNDIFLKSLKKEPIARYPVWLMRQAGRYLPEYRAIRQKYKSFLDFCKNVEDAAIVSLQP 60
Query: 70 LRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLD 129
+ +DA I+FSDILV+ + +G+ V G GPV L + L+ +G L
Sbjct: 61 V-DILGVDAVIMFSDILVLLEPMGIKVSFEAGEGPV----LDHNFDFKNLKSQGISGDLS 115
Query: 130 YVGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQVFESSADHLSREQF 178
YV + + + + K VP+IGF GAP + +++ ESS D + F
Sbjct: 116 YVFELLKVLKEK--SPVPVIGFCGAPFTLASYVIEK-ESSRDFTKTKVF 161
Score = 74.5 bits (175), Expect = 3e-12
Identities = 46/162 (28%), Positives = 79/162 (48%), Gaps = 7/162 (4%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L+ + ++SGA ++Q+F+S + LSR + E+ Y I ++ K P+
Sbjct: 180 LVEYIDHQIKSGADVIQIFDSWSMSLSRFAYKEYVYDYNAFIIKSIKQKHPN-----TPI 234
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
F +G+ ++ LG + + +DW+V + K + + QGNL+PQ L E I+
Sbjct: 235 IYFFRGSSSHIEDAVDLGADALSVDWSVCINDVCKRYPD-LVFQGNLEPQILLLDKENIR 293
Query: 268 TLTTEMVKKFGKHR-YIANLGHGITPQTPLESMTVFTETVHE 308
E V + ++ NLGHGITP +++ F E V E
Sbjct: 294 KHVEEFVMCIPRDTAFVVNLGHGITPDVSKDNVKYFVECVKE 335
>UniRef50_Q6KZ54 Cluster: Uroporphyrinogen decarboxylase; n=2;
Thermoplasmatales|Rep: Uroporphyrinogen decarboxylase -
Picrophilus torridus
Length = 331
Score = 100 bits (239), Expect = 5e-20
Identities = 94/321 (29%), Positives = 151/321 (47%), Gaps = 46/321 (14%)
Query: 26 DKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRYEHLDASIIFSDI 85
D +PVW MRQAGRYL E+ E + + +C PEL ++ P+ R ++DA+IIFSDI
Sbjct: 14 DTIPVWFMRQAGRYLKEYNEKKGRMTIKEICMDPELIAGISYDPV-RILNVDAAIIFSDI 72
Query: 86 LVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDY-VGKAITLTRHKIDG 144
+ +ALG +E PG + ++ D + E S Y + AI + + K
Sbjct: 73 TIPLEALGYKIEFLPGGPRIINGYIKNHDMKDIIYFE--ESNFKYKIYDAIKIFKEKY-- 128
Query: 145 KVPLIGFTGAPVE------SGAQLLQVFESSADHLSREQFTEF-------SIPYLK-DIR 190
PLIGF+G + +G + + LS ++F ++ I Y++ +R
Sbjct: 129 HFPLIGFSGGLITVLSYIIAGGPDSNLNLTKRSMLSDDKFNDYINIIKDMIIKYIRLQVR 188
Query: 191 SGVRA-KLTEKSLEQV-PMTIFAKGAGHSLDIQAQLGYETI------------------- 229
+GV A ++ + L + P T GH +I +++ I
Sbjct: 189 AGVDAIQIFDSWLGYLSPQTYENYIKGHIEEILSEINVPVIYFSTGTSSIIEKLSRLNVD 248
Query: 230 --GLDWTVDPTEARKIVGENITLQGNLDPQ-DLYKTPEEIKTLTTEMVKKFGKHRYIANL 286
+DW +D AR +V + LQGNLDP Y +K T++++ G+ YI NL
Sbjct: 249 YISVDWRLDMKLARSMVNKK-GLQGNLDPLIAAYNLRYALKE-TSDIINAAGRSSYIFNL 306
Query: 287 GHGITPQTPLESMTVFTETVH 307
GHG+ P+TP+E++ VH
Sbjct: 307 GHGVIPETPVENLKHIVNFVH 327
>UniRef50_O66667 Cluster: Uroporphyrinogen decarboxylase; n=1;
Aquifex aeolicus|Rep: Uroporphyrinogen decarboxylase -
Aquifex aeolicus
Length = 338
Score = 99.1 bits (236), Expect = 1e-19
Identities = 60/145 (41%), Positives = 89/145 (61%), Gaps = 8/145 (5%)
Query: 12 KNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVK-HDFFTVCRTPELACEVTLQPL 70
KND LLR+ G+ + + PVW+MRQAGRY+PE++++R + +F +C+ +LA E++L PL
Sbjct: 3 KNDLLLRSLRGEPIGRFPVWLMRQAGRYMPEYRKIRNRVKNFLELCKNVDLATEISLLPL 62
Query: 71 RRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDY 130
+ +DA IIFSDILV + LG+ VE G GP L ++ L+ S+ Y
Sbjct: 63 -KILGVDAIIIFSDILVPLEPLGVKVEFVEGEGP----KLSWSGKVSDLKKYDP-SQNAY 116
Query: 131 VGKAITLTRHKIDGKVPLIGFTGAP 155
V + I + D +VP+IGF GAP
Sbjct: 117 VYEIIKRVKEAQD-EVPVIGFAGAP 140
Score = 84.6 bits (200), Expect = 3e-15
Identities = 46/160 (28%), Positives = 84/160 (52%), Gaps = 9/160 (5%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
++ + +++GA ++Q+F+S ++LS E + E+ PY+ + S + K P+
Sbjct: 181 VLAYLKEQIKAGADVVQIFDSWVNNLSLEDYGEYVYPYVNYLISEL------KDFSDTPV 234
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
F +G+ +D+ + + +DW+VD E KI + QGNL+P LY + E I+
Sbjct: 235 IYFFRGSSSFIDLAVDYRADALSVDWSVDIPELFKIYDKG--FQGNLEPAVLYASEEVIE 292
Query: 268 TLTTEMVKKFG-KHRYIANLGHGITPQTPLESMTVFTETV 306
T ++++ K RY+ NLGHG+ P LE + + V
Sbjct: 293 EKTLGLLRRIPVKTRYVFNLGHGLAPDMELEKVKYLVDLV 332
>UniRef50_Q8EY41 Cluster: Uroporphyrinogen decarboxylase; n=5;
Bacteria|Rep: Uroporphyrinogen decarboxylase -
Leptospira interrogans
Length = 350
Score = 94.7 bits (225), Expect = 3e-18
Identities = 52/147 (35%), Positives = 84/147 (57%), Gaps = 3/147 (2%)
Query: 10 ELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQP 69
++ N+R G + PVW+MRQAGRY +Q +R K+ F +C+ P+LA EV P
Sbjct: 10 KMPNERYTNVLNGIAQKIPPVWMMRQAGRYHKHYQTLRTKYSFEELCKNPDLAAEVAYGP 69
Query: 70 LRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQP-EGAVSRL 128
+ ++ D +I+FSDIL +ALGM + + GPV +++ +++ L+ E ++S +
Sbjct: 70 VDEFD-FDVAILFSDILFPLEALGMGLR-YTDSGPVLDLEIRSKEDLNKLKSVEDSISFM 127
Query: 129 DYVGKAITLTRHKIDGKVPLIGFTGAP 155
+ KAI T K+ + LIGF G P
Sbjct: 128 QFQKKAIQRTLEKLPKEKSLIGFVGGP 154
Score = 46.4 bits (105), Expect = 0.001
Identities = 43/161 (26%), Positives = 70/161 (43%), Gaps = 20/161 (12%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
+E GA+L+ +F+++ LS E F E IP +K + K+ + +G
Sbjct: 199 LEGGAELILIFDTAGGDLSPELFREIVIPGIKTLSDFYPGKVG----------YYGRGTS 248
Query: 216 --HSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEM 273
H I+ G D + E K E+ +QGN D L+ EE K +
Sbjct: 249 SIHFEMIREITTLAGFGFDHRWNLREIFKT--ESRMIQGNFDQSLLFLGKEEFKKILMNY 306
Query: 274 VKKFGK----HR--YIANLGHGITPQTPLESMTVFTETVHE 308
+K F + R ++ LGHG+ P+TP ++ F E V +
Sbjct: 307 LKPFRELPPAERIGWVCGLGHGVMPKTPEYNVKTFVEIVRD 347
>UniRef50_Q1V1A2 Cluster: Uroporphyrinogen decarboxylase; n=2;
Candidatus Pelagibacter ubique|Rep: Uroporphyrinogen
decarboxylase - Candidatus Pelagibacter ubique HTCC1002
Length = 313
Score = 89.0 bits (211), Expect = 1e-16
Identities = 56/126 (44%), Positives = 76/126 (60%), Gaps = 7/126 (5%)
Query: 33 MRQAGRYLPEFQEVR-VKHDFFTVCRTPELACEVTLQPLRRYEHLDASIIFSDILVIPQA 91
MRQAGRYLPEF+E+R + DF +C L+ E+TLQPL+R++ LDA+IIFSDIL+IP
Sbjct: 1 MRQAGRYLPEFREIRKLNPDFINLCLNENLSSEITLQPLKRFD-LDAAIIFSDILMIPYG 59
Query: 92 LGMTVEMHPGVGPVFP-KPLQTPSEIDGLQPEGAVSRLDYVGKAI-TLTRHKIDGKVPLI 149
L V+ GP L+ S+ID + V +L V K+I ++ + LI
Sbjct: 60 LNQEVKFEKNFGPKLGLLDLEKISKIDEID---FVEKLYPVYKSIKKVSEDNLIKNKNLI 116
Query: 150 GFTGAP 155
GF GAP
Sbjct: 117 GFVGAP 122
Score = 63.3 bits (147), Expect = 8e-09
Identities = 42/140 (30%), Positives = 71/140 (50%), Gaps = 11/140 (7%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFS-IPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGA 214
+++GA ++Q+F+S A L + + +P L + KSL +P+ F +G
Sbjct: 169 IKNGATVIQIFDSWAGLLEEKDLPNYVYVPTLNLVNY-------IKSLN-IPVICFPRGI 220
Query: 215 GHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMV 274
+ + + + + +D+ VDP A K + I +QG LDP+ L E +K T + +
Sbjct: 221 KNYKNYCDIVKPDAVNIDYDVDPVSACKEI--KIPVQGGLDPKILLTDKENLKKETLKYL 278
Query: 275 KKFGKHRYIANLGHGITPQT 294
F H YI NLGHG+ P+T
Sbjct: 279 NTFKDHPYIFNLGHGVLPET 298
>UniRef50_A2ZVI4 Cluster: Uroporphyrinogen decarboxylase; n=2; Oryza
sativa|Rep: Uroporphyrinogen decarboxylase - Oryza
sativa subsp. japonica (Rice)
Length = 480
Score = 81.4 bits (192), Expect = 3e-14
Identities = 46/129 (35%), Positives = 75/129 (58%), Gaps = 4/129 (3%)
Query: 16 LLRAALGKS-VDKVPVWVMRQAGRYLPEFQEVRVKHDFFTV-CRTPELACEVTLQPLRRY 73
L+RAA G+ + + P W+MRQAGRY+ E+Q + +H F T EL E+TLQP R +
Sbjct: 48 LVRAARGEDGLPRPPAWMMRQAGRYMAEYQALAKRHPSFRERSETTELIVEITLQPWRAF 107
Query: 74 EHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGK 133
D I+FSDIL A+G+ ++ GPV P+++ ++ L P +L +VG+
Sbjct: 108 AP-DGVILFSDILTPLPAIGVPFDISDSKGPVIQSPVRSEEQVRELTPID-FEKLRFVGE 165
Query: 134 AITLTRHKI 142
++ + R ++
Sbjct: 166 SLKILRTEL 174
Score = 75.4 bits (177), Expect = 2e-12
Identities = 37/105 (35%), Positives = 60/105 (57%), Gaps = 5/105 (4%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAG 215
V SGAQ +Q+F+S L + ++S PY+K I + ++ + VP+ ++ G G
Sbjct: 278 VNSGAQCIQIFDSWGGQLPPHVWEQWSKPYIKQIVNKIKIECPN-----VPLVLYINGNG 332
Query: 216 HSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLY 260
L+ G + IGLDWTVD + R+ +G I++QGN+DP L+
Sbjct: 333 GLLERMTDTGVDVIGLDWTVDMADGRRRLGNKISVQGNVDPAFLF 377
>UniRef50_Q9HLB9 Cluster: Uroporphyrinogen decarboxylase; n=2;
Thermoplasma|Rep: Uroporphyrinogen decarboxylase -
Thermoplasma acidophilum
Length = 333
Score = 79.8 bits (188), Expect = 8e-14
Identities = 51/143 (35%), Positives = 74/143 (51%), Gaps = 4/143 (2%)
Query: 14 DRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRY 73
D +A G D++PVW MRQAGRYLP + + R + + +P++ +VT P+ R
Sbjct: 2 DPFRKAIKGYDHDRIPVWFMRQAGRYLPSYMKYRQRMGIEEMMSSPDVIVDVTHDPVDRI 61
Query: 74 EHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGK 133
+DA+IIF+DI +G+ V VGPV ++ S I ++ S V K
Sbjct: 62 -GVDAAIIFADITTPLSGMGLRVRFLDSVGPVVENNIE-KSGISAVEEFDPSSFSHPVLK 119
Query: 134 AITLTRHKIDGKVPLIGFTGAPV 156
AI+ R + PLIGF G PV
Sbjct: 120 AISKYRERYAD--PLIGFAGGPV 140
Score = 60.9 bits (141), Expect = 4e-08
Identities = 45/160 (28%), Positives = 69/160 (43%), Gaps = 10/160 (6%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
+I F + +G Q+F+S A +LS ++ F PY+ DI L E S +P
Sbjct: 180 IIEFARMQISAGVDAFQIFDSWAGYLSPGEYEHFVKPYVYDI-------LQELS-GSIP- 230
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIK 267
TI+ S L + +DW +D + + +QGNLDP + +
Sbjct: 231 TIYFSTMTSSYVADMDLPADFYSIDWRIDMKRFSAEIPDEKGIQGNLDPA-IVNYDYALH 289
Query: 268 TLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVH 307
+ + G+ RYI N GHG+ P T E + E VH
Sbjct: 290 EASKIVEAASGRDRYIFNTGHGLLPSTDPEKLKRLVEYVH 329
>UniRef50_A7BNH3 Cluster: Uroporphyrinogen decarboxylase; n=1;
Beggiatoa sp. SS|Rep: Uroporphyrinogen decarboxylase -
Beggiatoa sp. SS
Length = 126
Score = 71.7 bits (168), Expect = 2e-11
Identities = 34/80 (42%), Positives = 49/80 (61%), Gaps = 1/80 (1%)
Query: 229 IGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLTTEMVKKFGK-HRYIANLG 287
+GLDW + + AR VG+ + LQGN+DP LY +PE I+ ++ FGK + ++ NLG
Sbjct: 40 LGLDWKLPISMARDRVGDQVALQGNMDPCILYASPERIREEVATILASFGKGNGHVFNLG 99
Query: 288 HGITPQTPLESMTVFTETVH 307
HGI P E ++ F E VH
Sbjct: 100 HGIHPTIDPEHVSAFIEAVH 119
>UniRef50_O84752 Cluster: Uroporphyrinogen decarboxylase; n=8;
Chlamydiaceae|Rep: Uroporphyrinogen decarboxylase -
Chlamydia trachomatis
Length = 336
Score = 56.8 bits (131), Expect = 7e-07
Identities = 44/147 (29%), Positives = 72/147 (48%), Gaps = 11/147 (7%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSI-PYLKDIRSGVRAKLTEKSLEQVPMTIFAKGA 214
V++GA +Q+FESS+ L F ++ + P K IR K P+++F +
Sbjct: 185 VQAGAAAIQLFESSSLRLPPHLFAKYVVAPNTKLIRQ-------IKQTGNPPISLFCRCF 237
Query: 215 GHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEE--IKTLTTE 272
+G +T+ D+ V+ E + + ++QGN DP L P++ I L
Sbjct: 238 YQEFLSLYAIGADTLHPDYHVELPEVYRQIHSPGSIQGNFDPA-LLLLPQDALIAHLEAY 296
Query: 273 MVKKFGKHRYIANLGHGITPQTPLESM 299
+ + YI NLGHGI PQTP+E++
Sbjct: 297 LAPLKQQSHYIFNLGHGILPQTPIENV 323
Score = 48.4 bits (110), Expect = 2e-04
Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 13/138 (9%)
Query: 29 PVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRYEHLDASIIFSDILVI 88
P+W +RQ GRY+P++QE++ E E TL +DA+I+F+DIL I
Sbjct: 19 PIWFLRQVGRYIPQYQELKRNRSLKDFFLDTESIVEATLLG-PSLLGVDAAIVFADILSI 77
Query: 89 PQALGMTVEMHPGVGPVFPKPLQTPSE--IDGLQPEGAVSRLDYVGKAITLTRHKIDGKV 146
+ + PG P+ +P E I P+ S ++ +AI ++ V
Sbjct: 78 LEGFSVDYRFAPG-----PEVSYSPHEPLIFTKDPQETFS---FLLEAIQQLTKRL--TV 127
Query: 147 PLIGFTGAPVESGAQLLQ 164
PLI F +P + L++
Sbjct: 128 PLIAFAASPFTLASYLIE 145
>UniRef50_A5I1W7 Cluster: Putative methylcobamide:CoM
methyltransferase; n=4; Clostridium botulinum|Rep:
Putative methylcobamide:CoM methyltransferase -
Clostridium botulinum A str. ATCC 3502
Length = 350
Score = 52.4 bits (120), Expect = 1e-05
Identities = 44/141 (31%), Positives = 67/141 (47%), Gaps = 9/141 (6%)
Query: 168 SSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLGYE 227
SS +S +QF EFS+P L R + K+ EK+ + I K D+ G
Sbjct: 203 SSTSLISPKQFREFSLPAL---RKNIN-KIKEKTGGAPGIHICGKSKELWEDV-VNAGIS 257
Query: 228 TIGLDWTVDPTEARKIVGENITLQGNLDPQDL-YK-TPEEIKTLTTEMVKK--FGKHRYI 283
+D D EA+ I+G+ + + GN+ P D+ Y+ E I E +KK K YI
Sbjct: 258 NFSIDNAEDLEEAKNIMGDRVVITGNVPPVDIVYRGNKEAIFKSVKECIKKGHDSKKGYI 317
Query: 284 ANLGHGITPQTPLESMTVFTE 304
+ G I TP+E++ +F E
Sbjct: 318 LSTGCQIPMHTPIENIEMFME 338
>UniRef50_Q024B9 Cluster: Uroporphyrinogen decarboxylase; n=1;
Solibacter usitatus Ellin6076|Rep: Uroporphyrinogen
decarboxylase - Solibacter usitatus (strain Ellin6076)
Length = 357
Score = 50.4 bits (115), Expect = 6e-05
Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 9/146 (6%)
Query: 165 VFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQL 224
+ + ++ E + EF+ PYLK I + + LD
Sbjct: 205 ILDDIVGFINEEHYLEFAHPYLKRICDAFPDNWVKLYHNDAEVDA-------CLDHLPDA 257
Query: 225 GYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYK--TPEEIKTLTTEMVKKFGKHRY 282
G+ + TE ++ VG+ + L GN++P ++ TPEE+K T E+++ G
Sbjct: 258 GFNVLNWGKQRHITEVKRRVGDRMCLMGNVNPLEIAVRGTPEEVKDETLEVLEGAGGEGI 317
Query: 283 IANLGHGITPQTPLESMTVFTETVHE 308
I ++G G++P P E++ E + E
Sbjct: 318 ILSVGGGVSPGMPRENILAMLEALQE 343
>UniRef50_A3DJ55 Cluster: Methyltransferase MtaA/CmuA family; n=2;
Bacteria|Rep: Methyltransferase MtaA/CmuA family -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 372
Score = 48.8 bits (111), Expect = 2e-04
Identities = 39/146 (26%), Positives = 68/146 (46%), Gaps = 12/146 (8%)
Query: 168 SSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSL-DIQAQLGY 226
SS +S +QF EFS PYLK + + ++ KS+ T+ G + + ++ A+ G
Sbjct: 203 SSNTVISPKQFKEFSFPYLKRLIDYIHSR--GKSV-----TLHICGKTNKIWELMAEAGA 255
Query: 227 ETIGLDWTVDPTEARKIVGENITLQGNLDPQD--LYKTPEEIKTLTTEMVKKF--GKHRY 282
+ I +D EA++ +G + L GN+ P + L T ++K E V++ Y
Sbjct: 256 DCISIDNDASLLEAKQKIGHKVRLMGNVKPSETMLQGTVSDVKKAVFECVRQAYDNPKGY 315
Query: 283 IANLGHGITPQTPLESMTVFTETVHE 308
I G + TP ++ + V E
Sbjct: 316 IVASGCSLPTDTPFSNIHAMMDAVRE 341
>UniRef50_Q0AZU9 Cluster: Uroporphyrinogen decarboxylase; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Uroporphyrinogen decarboxylase - Syntrophomonas wolfei
subsp. wolfei (strain Goettingen)
Length = 357
Score = 47.6 bits (108), Expect = 4e-04
Identities = 35/114 (30%), Positives = 57/114 (50%), Gaps = 13/114 (11%)
Query: 168 SSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDI---QAQL 224
+S LS +QF EF+ PYL +KL ++ +E+ G S I A
Sbjct: 206 ASGSLLSVKQFREFAKPYL--------SKLADRVIERTGKGPMLHICGDSTPIWSDMADT 257
Query: 225 GYETIGLDWTVDPTEARKIVGENITLQGNLDPQD--LYKTPEEIKTLTTEMVKK 276
G T+ LD +D EA+K+VGE + + GN+ P D + + ++I+ E ++K
Sbjct: 258 GAPTLSLDNVIDLAEAKKVVGERVCIMGNVKPIDTIMKGSHQQIEAEVKECLRK 311
>UniRef50_Q6LYZ9 Cluster: Uroporphyrinogen decarboxylase; n=6;
Methanococcus|Rep: Uroporphyrinogen decarboxylase -
Methanococcus maripaludis
Length = 363
Score = 47.2 bits (107), Expect = 5e-04
Identities = 40/166 (24%), Positives = 77/166 (46%), Gaps = 13/166 (7%)
Query: 149 IGFTGAPVESGAQL-LQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
I T A +E G + + SS +S + F EFS PYLK + ++A+ T K +
Sbjct: 184 IALTDAVLEKGVGVTISEPLSSCTVVSPKHFREFSAPYLKRLIDHIKAR-TGK------L 236
Query: 208 TIFAKGAGHSL-DIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLY--KTPE 264
I G + D ++G + + +D D + + VG+ + + GN+DP + + E
Sbjct: 237 VIHICGITDPIWDDLVEMGVDVLSIDNVADMEKCAETVGDKMVIAGNVDPSAIMYAGSRE 296
Query: 265 EIKTLTTEMVKK--FGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
+++ T + K+ K ++ G + + P+E++ +T E
Sbjct: 297 DVRKATIKCAKQGLKAKKGFMIMSGCSLPVEVPIENIDAMMDTARE 342
>UniRef50_Q8PXZ6 Cluster: Methylcobalamin: Coenzyme M
methyltransferase; n=10; Methanosarcinaceae|Rep:
Methylcobalamin: Coenzyme M methyltransferase -
Methanosarcina mazei (Methanosarcina frisia)
Length = 342
Score = 45.6 bits (103), Expect = 0.002
Identities = 47/157 (29%), Positives = 72/157 (45%), Gaps = 13/157 (8%)
Query: 15 RLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEVTLQPLRRYE 74
RLL A G+ VDKVPV + Q G + E +V V + PEL ++ L
Sbjct: 12 RLLAALKGEPVDKVPVCSVTQTG--IVELMDV-VGAPWPEAHTNPELMAKLALAN-HELS 67
Query: 75 HLDASIIFSDILVIPQALGMTVEM-----HPGV-GPVFPKPLQTPSEIDGLQPEGAVSRL 128
L+A + + V+ +A+G + M P V G +PK L+ + L G R+
Sbjct: 68 GLEAVRLPYCLTVLVEAMGCEINMGTKNRQPSVTGHPYPKDLEGAAVPADLLQRG---RI 124
Query: 129 DYVGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQV 165
V +AI + R K+ VP++G PV + L+ V
Sbjct: 125 PVVLEAIKIIREKVGPDVPIVGGMEGPVTVASDLVSV 161
Score = 33.5 bits (73), Expect = 7.1
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 17/154 (11%)
Query: 151 FTGAPVESGAQLLQVFE--SSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMT 208
+ A VE+GA ++ + + +S D +S + F +F LK R + S+ V +
Sbjct: 189 YANAMVEAGADVIAIADPVASPDLMSPDSFRQF----LKS-----RLQKFASSVNSVTVL 239
Query: 209 IFAKGAGHSLDIQAQLGYETIGLDWTVDPTE-ARKIVGENITLQGNLD-PQDLYKTP-EE 265
L A G+E + ++ + + ++++G L GN+ P L P ++
Sbjct: 240 HICGNVNPILSDMADCGFEGLSVEEKIGSAKKGKEVIGTRARLVGNVSSPFTLLPGPVDK 299
Query: 266 IKTLTTEMVKKFGKHRYIANLGHGITPQTPLESM 299
IK E ++ G +A G GI P TPLE++
Sbjct: 300 IKAEAKEALE--GGIDVLAP-GCGIAPMTPLENV 330
>UniRef50_A6R5E7 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 552
Score = 44.8 bits (101), Expect = 0.003
Identities = 21/42 (50%), Positives = 31/42 (73%), Gaps = 2/42 (4%)
Query: 8 FPELKNDRLLRAALGKSVDKVPVWVMRQAGRYLPEFQEVRVK 49
F LKND LLRAA G+ V++ P+WVMRQA ++P +E +++
Sbjct: 511 FEPLKNDLLLRAARGEKVERPPIWVMRQA--FIPIQRENKIE 550
>UniRef50_Q0YLK8 Cluster: Uroporphyrinogen decarboxylase; n=1;
Geobacter sp. FRC-32|Rep: Uroporphyrinogen decarboxylase
- Geobacter sp. FRC-32
Length = 362
Score = 44.4 bits (100), Expect = 0.004
Identities = 43/166 (25%), Positives = 68/166 (40%), Gaps = 10/166 (6%)
Query: 148 LIGFTGAPVESGAQL-LQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVP 206
+I F A ++ GA++ L +S +S QF EF+ PYL+++ + V A P
Sbjct: 185 IIRFAVAAIKVGARIGLADPTASGTMISPRQFREFAQPYLQEVATAVAAVAGA-----AP 239
Query: 207 MTIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDP-QDLY-KTPE 264
G + LD VD EA+ VG + + GN+ P +Y P
Sbjct: 240 SLHICGNTSKIWPGMTATGASVLSLDDAVDIAEAKLQVGNKVAILGNIRPTAAMYLGKPG 299
Query: 265 EIKTLTTEMVKK--FGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
+++ E + K YI LG G+ TP E++ E
Sbjct: 300 DVRENARECLTKGWDNPKGYILGLGCGLPIDTPPENIHALVGAARE 345
>UniRef50_Q70E94 Cluster: Methylcobalamin:coenzyme M
methyltransferase; n=4; Methanobacteriaceae|Rep:
Methylcobalamin:coenzyme M methyltransferase -
Methanosphaera stadtmanae
Length = 338
Score = 44.0 bits (99), Expect = 0.005
Identities = 44/159 (27%), Positives = 75/159 (47%), Gaps = 19/159 (11%)
Query: 157 ESGAQLLQVFE--SSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGA 214
ESG ++ V + SS + L F+EF+ P L+D+ + + TE L +
Sbjct: 188 ESGVDVIAVADPTSSPELLDPNDFSEFAQPALEDLSAEME---TESILH------ICGNS 238
Query: 215 GHSLDIQAQLGYETIGLDWTVDPTEARKI---VGENITLQGNLDP-QDLYKTP-EEIKTL 269
L+ G+ I ++ VD TEA+++ G + GN+ Q L+ P EE+K
Sbjct: 239 RPILEEMLDCGFSGISVEEAVDMTEAQQVRAETGAETVMVGNVSTSQTLFSKPVEEVKAE 298
Query: 270 TTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
T+ ++K G + + G I P++PL ++ F E E
Sbjct: 299 VTQALEK-GVNVLAPSCG--IAPKSPLANLKAFVEARDE 334
>UniRef50_Q8AAW9 Cluster: Methylcobamide:CoM methyltransferase mtbA;
n=7; Bacteroides|Rep: Methylcobamide:CoM
methyltransferase mtbA - Bacteroides thetaiotaomicron
Length = 338
Score = 43.6 bits (98), Expect = 0.007
Identities = 40/164 (24%), Positives = 70/164 (42%), Gaps = 9/164 (5%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
+I + A +G + + E +A LS E ++S ++K+I V+ L
Sbjct: 175 IIRYCMALKATGVNGVVMAEPAAGLLSNEDCLQYSSVFVKEIVEKVQDDHFTVVLHNCGN 234
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYK--TPEE 265
T G+ G ++ EA K V + GNLDP L+K +PEE
Sbjct: 235 T------GNCTQAMVYTGAAAYHFGNKINMEEALKEVPADALAMGNLDPVSLFKMSSPEE 288
Query: 266 IKTLTTEMVKKFGKH-RYIANLGHGITPQTPLESMTVFTETVHE 308
+K T ++++ + ++ + G I P TPL ++ F + E
Sbjct: 289 MKKATLQLLEATAAYPNFVLSSGCDIPPYTPLANINAFYTALEE 332
>UniRef50_A6PPN3 Cluster: Uroporphyrinogen decarboxylase; n=1;
Victivallis vadensis ATCC BAA-548|Rep: Uroporphyrinogen
decarboxylase - Victivallis vadensis ATCC BAA-548
Length = 337
Score = 43.2 bits (97), Expect = 0.009
Identities = 39/158 (24%), Positives = 64/158 (40%), Gaps = 8/158 (5%)
Query: 148 LIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPM 207
L G+ A +G L + E +A LS + EF+ YLK I + V + V +
Sbjct: 173 LTGYAKAIRSTGVNGLVIAEPAAGLLSPDMCREFAADYLKKIIAAV-----QDDDFMVVL 227
Query: 208 TIFAKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYK--TPEE 265
A + G + L V E + + L GN+DP + K TPEE
Sbjct: 228 HNCGNAANRQISALVSTGAAALHLGNAVSLPELLPQIPPEVLLMGNIDPVGVLKNGTPEE 287
Query: 266 IKTLTTEMVKKFGK-HRYIANLGHGITPQTPLESMTVF 302
+ T ++++ Y+ + G + P LE++ F
Sbjct: 288 VYAKTAGLLRETAAWPNYVLSSGCDVPPGVSLENIRAF 325
>UniRef50_Q18UN1 Cluster: Uroporphyrinogen decarboxylase; n=2;
Desulfitobacterium hafniense|Rep: Uroporphyrinogen
decarboxylase - Desulfitobacterium hafniense (strain
DCB-2)
Length = 335
Score = 41.9 bits (94), Expect = 0.020
Identities = 40/158 (25%), Positives = 69/158 (43%), Gaps = 9/158 (5%)
Query: 154 APVESGAQLLQVFESSADH--LSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFA 211
A + GA + V + SA L E F + +P ++DI S + S + I
Sbjct: 183 ALLAQGAHISAVIDPSASQSILPSEMFGRYLLPTIRDIFSQFKGAGAMASW----LVITG 238
Query: 212 KGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDP-QDLYKTPEEIKTLT 270
G L Q G + G+D+ V EA K G+ + + GN+ P + + +TP+EI
Sbjct: 239 NSQG-LLPYYRQCGVDIAGIDYEVPLAEALKWEGDFL-ISGNIKPYRFVNQTPQEIIREG 296
Query: 271 TEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
E++ R+I + G + T E++ + V +
Sbjct: 297 KELISLAAGRRFILSSGCEVPLDTKPENLAALIKAVRD 334
>UniRef50_A6BKM2 Cluster: Putative uncharacterized protein; n=1;
Dorea longicatena DSM 13814|Rep: Putative
uncharacterized protein - Dorea longicatena DSM 13814
Length = 353
Score = 41.9 bits (94), Expect = 0.020
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 6/111 (5%)
Query: 167 ESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLGY 226
E +A LS +QF EF IPY + K E I L+ ++G
Sbjct: 202 EPTASLLSPKQFREFVIPYYVKVMD----KWKEWGSHGSGFHICGDTT-KLLETFPEMGI 256
Query: 227 ETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYK-TPEEIKTLTTEMVKK 276
I +D +VD A++ VG+ +++ GN+ P ++ TPE I+ + +K
Sbjct: 257 RGISIDSSVDIAYAKETVGDKLSIMGNVSPMEILNGTPESIEQAVIDCFRK 307
>UniRef50_Q8PZI7 Cluster: Methylcobalamin:Coenzyme M
methyltransferase MtbA; n=6; Methanosarcinaceae|Rep:
Methylcobalamin:Coenzyme M methyltransferase MtbA -
Methanosarcina mazei (Methanosarcina frisia)
Length = 345
Score = 41.5 bits (93), Expect = 0.027
Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 214 AGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQD--LYKTPEEIKTLTT 271
AG SL ++ G+E I ++ V A++ +G+ L GN+ P L+ TP+ +K
Sbjct: 246 AGDSLRTLSECGFEAISIEEKVSLKAAKEAIGDRARLIGNVSPSRTLLFGTPDAVK---A 302
Query: 272 EMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
E + I G GI P TPL ++ E E
Sbjct: 303 EAKQCLSAGVDILAPGCGIAPGTPLSNIRALVEARDE 339
>UniRef50_Q2RIW2 Cluster: Putative uncharacterized protein; n=3;
Clostridia|Rep: Putative uncharacterized protein -
Moorella thermoacetica (strain ATCC 39073)
Length = 438
Score = 40.3 bits (90), Expect = 0.062
Identities = 45/141 (31%), Positives = 72/141 (51%), Gaps = 14/141 (9%)
Query: 173 LSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHS-LDIQAQLGY-ETIG 230
LS +Q+ F P LK + +G L E+ L VP +FA+G+ +S L++ L +T+
Sbjct: 302 LSDKQYRTFYWPTLKKVITG----LIEEGL--VPF-LFAEGSYNSRLEVIRDLPKGKTVW 354
Query: 231 LDWTVDPTEARKIVGENITLQGNLDPQDLYK--TPEEIKTLTTEMVKKFGKH-RYIANLG 287
L D A++I+G+ + GN+ P L TPEEIK +++K GK +I + G
Sbjct: 355 LFDDTDMARAKEILGDIACIAGNV-PITLLSLGTPEEIKEYCKQLIKTAGKDGGFILSSG 413
Query: 288 HGITPQTPLESMTVFTETVHE 308
I P E++ E+ E
Sbjct: 414 ATIDNIKP-ENLRALIESARE 433
>UniRef50_Q2RLD3 Cluster: Uroporphyrinogen decarboxylase; n=1;
Moorella thermoacetica ATCC 39073|Rep: Uroporphyrinogen
decarboxylase - Moorella thermoacetica (strain ATCC
39073)
Length = 343
Score = 39.9 bits (89), Expect = 0.081
Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 11/145 (7%)
Query: 154 APVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKG 213
A V S + + V + LS++ + EF+ PYLK+I + + + F+
Sbjct: 193 AEVLSEVEGIMVLDDIVGFLSQDDYLEFAHPYLKEIFDAFPQCIKMYHNDSDNIVCFSYL 252
Query: 214 AGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYK--TPEEIKTLTT 271
S++I D + R++VG I L GN+ P D+ TP+ +
Sbjct: 253 QDLSINI--------FNFTHLQDIAKVRQLVGNKICLLGNIPPLDVLTNGTPDMVAEAAV 304
Query: 272 EMVKKFG-KHRYIANLGHGITPQTP 295
+ + G K I + G G +P TP
Sbjct: 305 NCLNQHGNKAGIILSAGGGTSPGTP 329
>UniRef50_Q2RG09 Cluster: Uroporphyrinogen decarboxylase; n=1;
Moorella thermoacetica ATCC 39073|Rep: Uroporphyrinogen
decarboxylase - Moorella thermoacetica (strain ATCC
39073)
Length = 352
Score = 39.5 bits (88), Expect = 0.11
Identities = 35/135 (25%), Positives = 65/135 (48%), Gaps = 12/135 (8%)
Query: 173 LSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLGYETIGLD 232
LSRE F EF PY+K++ + V EK+ ++ H LD+ + +
Sbjct: 217 LSRELFDEFIHPYMKEVFTHV-----EKATLRIYHN--ENNYPHLLDLMRDIPANVCHIG 269
Query: 233 WTVDPTEARKIVGENITLQGNLDP--QDLYKTPEEIKTLTTEMVKKFGKHRYI-ANLGHG 289
D E+++++ + + GN+ P + L T EEI+ +++ G+ + + G G
Sbjct: 270 PKHDLVESKRVLKK--CVMGNVHPIQELLLGTNEEIEAKCKTIIETAGRGGGLWLSTGGG 327
Query: 290 ITPQTPLESMTVFTE 304
+ P+TP+E M V +
Sbjct: 328 MAPETPVEKMQVLID 342
>UniRef50_Q0AZU7 Cluster: Uroporphyrinogen decarboxylase; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Uroporphyrinogen decarboxylase - Syntrophomonas wolfei
subsp. wolfei (strain Goettingen)
Length = 348
Score = 39.1 bits (87), Expect = 0.14
Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 15/165 (9%)
Query: 148 LIGFTGAPVESGAQLLQVFE--SSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQV 205
LI F + +++GAQ++ + + + + L F EF++PY+ I L E E
Sbjct: 183 LIVFGRSMLQAGAQIINIADPGGTEEILGPRHFAEFALPYINRI-------LNELQGEYQ 235
Query: 206 PMTIFAKGAGHSLDIQA-QLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKT-P 263
+ G S+ + QL I +D T ++ R + E + + GN+ L P
Sbjct: 236 ASMVHICGRLQSIFTEINQLATNAISIDSTTSISKLRSALREKVVV-GNISTYLLQNAQP 294
Query: 264 EEIKTLTTEMVKKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
+K ++K I + GI+P TPL ++ VH+
Sbjct: 295 GRVKATGFNCLRK---GITILSPACGISPATPLANLQAMVSAVHD 336
>UniRef50_A7CVU8 Cluster: Uroporphyrinogen decarboxylase HemE; n=1;
Opitutaceae bacterium TAV2|Rep: Uroporphyrinogen
decarboxylase HemE - Opitutaceae bacterium TAV2
Length = 94
Score = 38.7 bits (86), Expect = 0.19
Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 222 AQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYK--TPEEIKTLTTEMVKKFGK 279
A LG + + LD+ E G TL G +DP ++ TP++++ ++ +
Sbjct: 2 ATLGLDAVELDYATPLDEIVTHFGSRTTLFGTIDPSGIFNFGTPDKVRAEAEKIFTAYRD 61
Query: 280 H-RYIANLGHGITPQTPLESMTVFTETVHEAI 310
+ R + G + P TP E++ H +
Sbjct: 62 NPRLVIGAGCALPPTTPAENIHAIVNFAHSGV 93
>UniRef50_A5I1X6 Cluster: Putative methylcobamide:CoM
methyltransferase; n=4; Clostridium botulinum|Rep:
Putative methylcobamide:CoM methyltransferase -
Clostridium botulinum A str. ATCC 3502
Length = 359
Score = 37.5 bits (83), Expect = 0.43
Identities = 32/141 (22%), Positives = 59/141 (41%), Gaps = 9/141 (6%)
Query: 168 SSADHLSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLGYE 227
S + +S +QF +F PYL+ G+ K+T K P H ++
Sbjct: 209 SCGNLISGKQFEKFVEPYLRKTVDGIY-KITGKK----PSLHICGKTKHIWSRLGKMNIS 263
Query: 228 TIGLDWTVDPTEARKIVGENITLQGNLDPQDLYK--TPEEIKTLTTEMVKKF--GKHRYI 283
T +D D E + ++G+ + + GN+DP + + T E++ ++K Y+
Sbjct: 264 TFSVDNCEDIGELKAVLGDKVCIVGNVDPVSVIRNGTLEDVYDTVKLCIEKVADSPKGYV 323
Query: 284 ANLGHGITPQTPLESMTVFTE 304
G I P+E++ E
Sbjct: 324 VGSGCDIPGGAPVENIKAMIE 344
>UniRef50_Q8THF8 Cluster: Methylcobamide:CoM methyltransferase
isozyme M; n=4; Methanosarcina acetivorans|Rep:
Methylcobamide:CoM methyltransferase isozyme M -
Methanosarcina acetivorans
Length = 368
Score = 36.3 bits (80), Expect = 1.0
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 218 LDIQAQLGYETIGLDWTV-DPTEARKIVGENITLQGNLDPQD--LYKTPEEIKTLTTEMV 274
L+ ++ G+E I ++ V D A+K +G+ I L GN+ L+ +PE++K E
Sbjct: 246 LETLSECGFEGISVEEKVWDLKGAKKSLGKGICLIGNVASSSTLLFGSPEDVKA---EAR 302
Query: 275 KKFGKHRYIANLGHGITPQTPLESMTVFTETVHE 308
K I GI P TPLE+M E E
Sbjct: 303 KSLEGGVDILAPSCGIAPLTPLENMKALVEARDE 336
>UniRef50_Q5JEA5 Cluster: Hypothetical membrane protein, conserved;
n=1; Thermococcus kodakarensis KOD1|Rep: Hypothetical
membrane protein, conserved - Pyrococcus kodakaraensis
(Thermococcus kodakaraensis)
Length = 129
Score = 35.9 bits (79), Expect = 1.3
Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Query: 69 PLRRYEHLDASIIFSDILVIPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRL 128
PL+ L ++ DIL+ P LG +E P GP ++ ++ L PEG V
Sbjct: 35 PLKVSVPLLVLLLLKDILIAPYVLGGGLEKRPLTGPEALIGMEA-VVVEDLSPEGIVKVG 93
Query: 129 DYVGKAITLT-RHKIDGKVPLIGFTG 153
+ + + + L R K KV ++GF G
Sbjct: 94 NELWRGVCLNGRAKRGEKVRIVGFRG 119
>UniRef50_O67753 Cluster: Type III pantothenate kinase; n=1; Aquifex
aeolicus|Rep: Type III pantothenate kinase - Aquifex
aeolicus
Length = 229
Score = 35.9 bits (79), Expect = 1.3
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 1/78 (1%)
Query: 173 LSREQFTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTIFAKGAGHSLDIQAQLGYETIGLD 232
LS E+F + P LK + V+ +EK ++P F K + + + ET+G D
Sbjct: 29 LSHEEFLKEEFPKLKALGISVKQSFSEKVRGKIPKIKFLKKENFPIQVDYKTP-ETLGTD 87
Query: 233 WTVDPTEARKIVGENITL 250
A+K G+N+ +
Sbjct: 88 RVALAYSAKKFYGKNVVV 105
>UniRef50_UPI00015557E4 Cluster: PREDICTED: similar to T cell receptor
beta chain variable region; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to T cell receptor beta
chain variable region - Ornithorhynchus anatinus
Length = 1658
Score = 35.1 bits (77), Expect = 2.3
Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 11/77 (14%)
Query: 93 GMTVEMHPGVGPV--FPKPLQTPSEIDGLQPEGAVSRL------DYVGKAITLTRHKIDG 144
G+ + HP P P P+ +P+ D + P G SRL + G+ LTRH + G
Sbjct: 1037 GLPIRSHPPSPPTPPIPVPVPSPTNPDEVAPSGRGSRLCLLRFSELAGQWQALTRHPVPG 1096
Query: 145 KV---PLIGFTGAPVES 158
V PL GAP S
Sbjct: 1097 TVLPHPLRARHGAPAPS 1113
>UniRef50_Q2RG07 Cluster: Methyltransferase MtaA/CmuA; n=2; Moorella
thermoacetica ATCC 39073|Rep: Methyltransferase
MtaA/CmuA - Moorella thermoacetica (strain ATCC 39073)
Length = 349
Score = 35.1 bits (77), Expect = 2.3
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 223 QLGYETIGLDWTVDPTEARKIVGENITLQGNL-DPQDLYK-TPEEIKTLTTEMVKKFGKH 280
+ G++ D VD A+++ G ++L GN+ +P L TPE++K T ++ +
Sbjct: 253 EAGFDAFHFDSKVDAKLAKELAGNKMSLIGNINNPVTLLAGTPEDVKKETLYAIEAGVE- 311
Query: 281 RYIANLGHGITPQTPLESMTVFTETVHE 308
I I TPLE++ TET E
Sbjct: 312 --IVGPECAIPLTTPLENILAITETAKE 337
>UniRef50_Q0LDB2 Cluster: Putative uncharacterized protein; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep: Putative
uncharacterized protein - Herpetosiphon aurantiacus ATCC
23779
Length = 553
Score = 35.1 bits (77), Expect = 2.3
Identities = 37/118 (31%), Positives = 52/118 (44%), Gaps = 17/118 (14%)
Query: 76 LDASIIFS------DILVIPQALGMTVEMHPGV--GPVFP----KPLQTPSEIDGLQP-E 122
LDA ++FS L +PQA + V + P G V KPL + I ++P E
Sbjct: 101 LDAPVVFSATDYSSQTLELPQAASLDVVLRPSTVRGSVVDSTTGKPLTKGTVIAMVKPFE 160
Query: 123 GAVSRLDYVGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQV-FESSADHLSREQFT 179
GA Y G A+T+ R DG L T P + Q+L + + LS +FT
Sbjct: 161 GADETYPYTGTAVTMARLNADGTYEL---TDVPENAQIQVLSPGYRKAWTALSEGKFT 215
>UniRef50_A5GK46 Cluster: Possible thiopurine S-methyltransferase;
n=2; Synechococcus|Rep: Possible thiopurine
S-methyltransferase - Synechococcus sp. (strain WH7803)
Length = 210
Score = 34.7 bits (76), Expect = 3.1
Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Query: 213 GAGHSLDIQAQLGYETIGLDWTVDP-TEARKIVGENITLQ 251
G GH + A+LG+E IGLD++ + EAR++ GE+ L+
Sbjct: 53 GRGHEAALLARLGFEVIGLDFSSEAIREARRLHGEHPRLR 92
>UniRef50_Q01R38 Cluster: Putative methyltransferase CmuC; n=1;
Solibacter usitatus Ellin6076|Rep: Putative
methyltransferase CmuC - Solibacter usitatus (strain
Ellin6076)
Length = 438
Score = 34.3 bits (75), Expect = 4.0
Identities = 31/138 (22%), Positives = 54/138 (39%), Gaps = 11/138 (7%)
Query: 178 FTEFSIPYLKDIRSGVRAKLTEKSLEQVPMTI---FAKGAGHSLDIQAQLGYETIGLDWT 234
F E PY K + V A T K + ++ F D+ + G+D
Sbjct: 298 FRELWFPYYKRVNEWVHANTTWKCFKHSCGSVERFFDSFIDAGFDVINPVQCSAAGMD-- 355
Query: 235 VDPTEARKIVGENITLQGN-LDPQDL--YKTPEEIKTLTTEMVKKFGKHR-YIANLGHGI 290
P E ++ G + G +D Q + TP+E++ + F ++ N H +
Sbjct: 356 --PVELKRKYGSRLVFWGGGVDTQKTLPFGTPQEVREEVLRRCEIFAPGGGFVFNSIHNL 413
Query: 291 TPQTPLESMTVFTETVHE 308
TP+E++ + VHE
Sbjct: 414 QAGTPVENIAAMVDAVHE 431
>UniRef50_A6PSC8 Cluster: Regulatory protein GntR, HTH; n=1;
Victivallis vadensis ATCC BAA-548|Rep: Regulatory
protein GntR, HTH - Victivallis vadensis ATCC BAA-548
Length = 341
Score = 34.3 bits (75), Expect = 4.0
Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
Query: 88 IPQALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSR 127
IP+ LG+ ++ GV P FP PL T EID + G +S+
Sbjct: 274 IPETLGLVTHVNRGVEPFFPLPL-TRLEIDPAEVAGQISQ 312
>UniRef50_UPI00006600F2 Cluster: Zinc fingers and homeoboxes protein
2 (Zinc finger and homeodomain protein 2)
(Alpha-fetoprotein regulator 1) (AFP regulator 1)
(Regulator of AFP).; n=1; Takifugu rubripes|Rep: Zinc
fingers and homeoboxes protein 2 (Zinc finger and
homeodomain protein 2) (Alpha-fetoprotein regulator 1)
(AFP regulator 1) (Regulator of AFP). - Takifugu
rubripes
Length = 637
Score = 33.9 bits (74), Expect = 5.3
Identities = 16/46 (34%), Positives = 26/46 (56%)
Query: 101 GVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAITLTRHKIDGKV 146
G G VFP ++TP + L + VS+LD++ + +T I+G V
Sbjct: 203 GAGSVFPATVKTPESLQALYKQQEVSQLDHLVQKDQITAVTINGTV 248
>UniRef50_O74539 Cluster: Peroxide stress-activated histidine kinase
mak3; n=1; Schizosaccharomyces pombe|Rep: Peroxide
stress-activated histidine kinase mak3 -
Schizosaccharomyces pombe (Fission yeast)
Length = 2344
Score = 33.9 bits (74), Expect = 5.3
Identities = 21/95 (22%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 137 LTRHKIDGKVPLIGFTGAPVESGAQLLQVFESSADHLSREQFTEFSIPYLKDIRSGVRAK 196
+ R + ++ +G E G + LQ+FES D+ + F ++ +P + R +
Sbjct: 2220 IVRMTLKKQLEHLGMDVDAAEDGKETLQIFESHPDNYYQVCFVDYHMPVYDGLEVTRRMR 2279
Query: 197 LTEKSLEQVPMTIFAKGAGHSLDIQAQLGYETIGL 231
E+ P+ IFA A ++ Q ++ +G+
Sbjct: 2280 KIERKHGCAPLPIFALTADMQPTMETQ--FQEVGI 2312
>UniRef50_UPI000038CE2D Cluster: COG3321: Polyketide synthase modules
and related proteins; n=1; Nostoc punctiforme PCC
73102|Rep: COG3321: Polyketide synthase modules and
related proteins - Nostoc punctiforme PCC 73102
Length = 2372
Score = 33.5 bits (73), Expect = 7.1
Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 12/73 (16%)
Query: 90 QALGMTVEMHPGVGPVFPKPLQTPSEIDGLQPEGAVSRLDYVGKAITLTRHKIDGKVPLI 149
+ LG +E++P + PKP P E+ L+ ++ +Y+GK + +I G +P
Sbjct: 1336 EILGALLELYPDL----PKP--DPEEVGQLRTLAQIA--EYMGKIAS----EISGAIPAT 1383
Query: 150 GFTGAPVESGAQL 162
GF AP +SG+ L
Sbjct: 1384 GFVNAPNDSGSGL 1396
>UniRef50_Q2F9X4 Cluster: Putative uncharacterized protein; n=1;
Vibrio sp. DAT722|Rep: Putative uncharacterized protein
- Vibrio sp. DAT722
Length = 223
Score = 33.5 bits (73), Expect = 7.1
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 4/73 (5%)
Query: 134 AITLTRHKIDGKVPLIGFTGAPVESGAQLL-QVFESSADHLSREQFTEFSI--PYLKDIR 190
AI +TRHK++ V +I P+ G+ + ++ LS Q + + Y+KDI
Sbjct: 59 AIAITRHKLEMNVHMIHSGTMPLPVGSYIFDNYYKEVVSELSSSQRRSYQLIHHYVKDIN 118
Query: 191 SGVRAKLTEKSLE 203
+ + LT+K++E
Sbjct: 119 ASIE-NLTKKNIE 130
>UniRef50_Q11FK7 Cluster: Molybdopterin binding domain; n=4;
Rhizobiales|Rep: Molybdopterin binding domain -
Mesorhizobium sp. (strain BNC1)
Length = 375
Score = 33.5 bits (73), Expect = 7.1
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 144 GKVPLIGFTGAPVESGAQLLQVFESSADHLS-REQFTEFSIPYLKDIRSGV-RAKLTEKS 201
GKVP+I G+P ++ A L + + DHLS R + + ++P + + S + +++
Sbjct: 266 GKVPVIALPGSPDQAFAAFLALVQPVLDHLSGRSERSGITLPLSRKVPSAIGLSEIALLG 325
Query: 202 LEQVPMTIFAKGAGHSLD 219
LEQ A G SLD
Sbjct: 326 LEQGAWAPLAVG-NFSLD 342
>UniRef50_A7CT59 Cluster: Putative uncharacterized protein; n=1;
Opitutaceae bacterium TAV2|Rep: Putative uncharacterized
protein - Opitutaceae bacterium TAV2
Length = 372
Score = 33.5 bits (73), Expect = 7.1
Identities = 19/75 (25%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Query: 235 VDPTEARKIVGENITLQGNLDPQDLYK--TPEEIKTLTTEMVKKFGKHR-YIANLGHGIT 291
+D E +++ G+++ G ++ Q T ++ T + ++ GK YI H +
Sbjct: 293 MDRAELKRLFGKDLIFHGGIENQKTLPMGTTRDVVAETRKCMETLGKDGGYICCSSHNVQ 352
Query: 292 PQTPLESMTVFTETV 306
TPLE++ ETV
Sbjct: 353 AGTPLENILAMIETV 367
>UniRef50_A4QTQ9 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1766
Score = 33.5 bits (73), Expect = 7.1
Identities = 29/124 (23%), Positives = 53/124 (42%), Gaps = 5/124 (4%)
Query: 156 VESGAQLLQVFESSADHLSREQFTEFSIPYL-----KDIRSGVRAKLTEKSLEQVPMTIF 210
V S A+LL F + +H+ + + I + KD + + A +K M F
Sbjct: 1043 VTSAAELLSSFVIAYEHIPSHRKRDMFISLIENLGPKDFLAALVAMFVDKYGTTDSMVAF 1102
Query: 211 AKGAGHSLDIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQDLYKTPEEIKTLT 270
K +S ++ QL + LD D + + + + + D QDL+KT + TL
Sbjct: 1103 CKDLMNSFGVEVQLQSLVMLLDLVSDCLQPKPTLAATLFNRNTDDDQDLHKTALKELTLL 1162
Query: 271 TEMV 274
+++
Sbjct: 1163 PKVL 1166
>UniRef50_Q2NG99 Cluster: MtaA1; n=1; Methanosphaera stadtmanae DSM
3091|Rep: MtaA1 - Methanosphaera stadtmanae (strain DSM
3091)
Length = 339
Score = 33.5 bits (73), Expect = 7.1
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 10/92 (10%)
Query: 223 QLGYETIGLDWTVDPTEARKI---VGENITLQGNLDPQD--LYKTPEEIKTLTTEMVKKF 277
++ + + ++ +++ EAR + + + + GN+ L KT E+K E VK+
Sbjct: 246 EINFNGLSIEESINTGEARMVKEDLSSDTVIIGNISSTQTLLNKTTNEVK----EEVKEI 301
Query: 278 GKHRY-IANLGHGITPQTPLESMTVFTETVHE 308
KH I GI P+TPLE++ F E +E
Sbjct: 302 LKHGTDILAPSCGIAPKTPLENIKAFVEARNE 333
>UniRef50_UPI00015B4E9B Cluster: PREDICTED: similar to leukocyte
receptor cluster (lrc) member; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to leukocyte
receptor cluster (lrc) member - Nasonia vitripennis
Length = 884
Score = 33.1 bits (72), Expect = 9.3
Identities = 20/88 (22%), Positives = 36/88 (40%), Gaps = 2/88 (2%)
Query: 115 EIDGLQPEGAVSRLDYVGKAITLTRHKIDGKVPLIGFTGAPVESGAQLLQVFESSADHLS 174
++ L + + D+ G I T ++ P + T AP S + + V S DH+
Sbjct: 614 QVSSLIKDDPTAEFDFTGLHIVGTCRDLEK--PYLRLTSAPAASAVRPVSVLRKSLDHVK 671
Query: 175 REQFTEFSIPYLKDIRSGVRAKLTEKSL 202
+ T+ Y D +R LT + +
Sbjct: 672 KRWATQQDYRYACDQLKSIRQDLTVQGI 699
>UniRef50_A0BYF6 Cluster: Chromosome undetermined scaffold_137,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_137,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 571
Score = 33.1 bits (72), Expect = 9.3
Identities = 17/77 (22%), Positives = 40/77 (51%), Gaps = 3/77 (3%)
Query: 10 ELKNDRLLRAALGKSVDK--VPVWVMRQAGRYLPEFQEVRVKHDFFTVCRTPELACEV-T 66
++ D+++ + L K +++ + V+V+ AG Y+ EF + +C + C++
Sbjct: 483 QMVRDKIIHSLLIKQINEKWLQVYVLSSAGTYIKEFIHSDLDRTVPNLCSLLQNECDIYQ 542
Query: 67 LQPLRRYEHLDASIIFS 83
L ++ YE +D +I +
Sbjct: 543 LDVIKLYEKIDEDVIIN 559
>UniRef50_A7TLW4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 794
Score = 33.1 bits (72), Expect = 9.3
Identities = 15/40 (37%), Positives = 20/40 (50%)
Query: 219 DIQAQLGYETIGLDWTVDPTEARKIVGENITLQGNLDPQD 258
DIQ Q + G+DWT ++G NI L GN +D
Sbjct: 55 DIQVQAYAKLSGVDWTYYVKHVEILIGRNINLDGNSQKKD 94
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.136 0.398
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 356,937,088
Number of Sequences: 1657284
Number of extensions: 15176598
Number of successful extensions: 33352
Number of sequences better than 10.0: 106
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 32963
Number of HSP's gapped (non-prelim): 183
length of query: 310
length of database: 575,637,011
effective HSP length: 101
effective length of query: 209
effective length of database: 408,251,327
effective search space: 85324527343
effective search space used: 85324527343
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 72 (33.1 bits)
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